data_9J0A
# 
_entry.id   9J0A 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9J0A         pdb_00009j0a 10.2210/pdb9j0a/pdb 
WWPDB D_1300050104 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-19 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9J0A 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-02 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhangmj@sustech.edu.cn 
_pdbx_contact_author.name_first         Mingjie 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9404-0190 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Liu, H.'   1 ?                   
'Cai, Q.'   2 0000-0002-4525-4261 
'Zhang, M.' 3 0000-0001-9404-0190 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Proc.Natl.Acad.Sci.USA 
_citation.journal_id_ASTM           PNASA6 
_citation.journal_id_CSD            0040 
_citation.journal_id_ISSN           1091-6490 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            122 
_citation.language                  ? 
_citation.page_first                e2417346122 
_citation.page_last                 e2417346122 
_citation.title                     
'ANKRD11 binding to cohesin suggests a connection between KBG syndrome and Cornelia de Lange syndrome.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1073/pnas.2417346122 
_citation.pdbx_database_id_PubMed   39847329 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Liu, H.'   1  0009-0003-1067-8747 
primary 'Li, H.'    2  ?                   
primary 'Cai, Q.'   3  0000-0002-4525-4261 
primary 'Zhang, J.' 4  0000-0001-8437-1471 
primary 'Zhong, H.' 5  0000-0001-6106-7661 
primary 'Hu, G.'    6  ?                   
primary 'Zhao, S.'  7  ?                   
primary 'Lu, Y.'    8  ?                   
primary 'Mao, Y.'   9  ?                   
primary 'Lu, Y.'    10 ?                   
primary 'Yao, H.'   11 0000-0003-2144-0147 
primary 'Zhang, M.' 12 0000-0001-9404-0190 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Cohesin subunit SA-2'                        113875.312 2  ? ? ? ? 
2 polymer man '64-kDa C-terminal product'                   16308.873  2  ? ? ? ? 
3 polymer man 'Ankyrin repeat domain-containing protein 11' 4783.156   2  ? ? ? ? 
4 water   nat water                                         18.015     14 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'SCC3 homolog 2,Stromal antigen 2' 
2 '64-kDa carboxy-terminal product'  
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;GPGSENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDED
SGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVAL
NLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIW
MKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLT
LVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGLMKRRGRQGPNANLVKTLVFFFLESELHE
HAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKT
QLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKT
YHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKL
LKTGIENGDMPEQIVIHALQCAHYVILWQLAKITESTSTKEDLLRLKKQMRVFCQICQHYLTNVNTTVKEQAFTILCDIL
MIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYT
VVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRF
ALTFGLDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRRE
DVWLPLMSYRNSLLAGGDDDTMSVI
;
;GPGSENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDED
SGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVAL
NLSINMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIW
MKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLT
LVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGLMKRRGRQGPNANLVKTLVFFFLESELHE
HAAYLVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKT
QLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKT
YHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKL
LKTGIENGDMPEQIVIHALQCAHYVILWQLAKITESTSTKEDLLRLKKQMRVFCQICQHYLTNVNTTVKEQAFTILCDIL
MIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYT
VVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRF
ALTFGLDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRRE
DVWLPLMSYRNSLLAGGDDDTMSVI
;
A,D ? 
2 'polypeptide(L)' no no 
;GPGSDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPT
KKLMMWKETGGVEKLFFLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEF
;
;GPGSDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPT
KKLMMWKETGGVEKLFFLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEF
;
B,E ? 
3 'polypeptide(L)' no no GPGSPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKEAKAN GPGSPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKEAKAN C,F ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   GLY n 
1 4   SER n 
1 5   GLU n 
1 6   ASN n 
1 7   MET n 
1 8   MET n 
1 9   LEU n 
1 10  PHE n 
1 11  GLU n 
1 12  VAL n 
1 13  VAL n 
1 14  LYS n 
1 15  MET n 
1 16  GLY n 
1 17  LYS n 
1 18  SER n 
1 19  ALA n 
1 20  MET n 
1 21  GLN n 
1 22  SER n 
1 23  VAL n 
1 24  VAL n 
1 25  ASP n 
1 26  ASP n 
1 27  TRP n 
1 28  ILE n 
1 29  GLU n 
1 30  SER n 
1 31  TYR n 
1 32  LYS n 
1 33  HIS n 
1 34  ASP n 
1 35  ARG n 
1 36  ASP n 
1 37  ILE n 
1 38  ALA n 
1 39  LEU n 
1 40  LEU n 
1 41  ASP n 
1 42  LEU n 
1 43  ILE n 
1 44  ASN n 
1 45  PHE n 
1 46  PHE n 
1 47  ILE n 
1 48  GLN n 
1 49  CYS n 
1 50  SER n 
1 51  GLY n 
1 52  CYS n 
1 53  LYS n 
1 54  GLY n 
1 55  VAL n 
1 56  VAL n 
1 57  THR n 
1 58  ALA n 
1 59  GLU n 
1 60  MET n 
1 61  PHE n 
1 62  ARG n 
1 63  HIS n 
1 64  MET n 
1 65  GLN n 
1 66  ASN n 
1 67  SER n 
1 68  GLU n 
1 69  ILE n 
1 70  ILE n 
1 71  ARG n 
1 72  LYS n 
1 73  MET n 
1 74  THR n 
1 75  GLU n 
1 76  GLU n 
1 77  PHE n 
1 78  ASP n 
1 79  GLU n 
1 80  ASP n 
1 81  SER n 
1 82  GLY n 
1 83  ASP n 
1 84  TYR n 
1 85  PRO n 
1 86  LEU n 
1 87  THR n 
1 88  MET n 
1 89  ALA n 
1 90  GLY n 
1 91  PRO n 
1 92  GLN n 
1 93  TRP n 
1 94  LYS n 
1 95  LYS n 
1 96  PHE n 
1 97  LYS n 
1 98  SER n 
1 99  SER n 
1 100 PHE n 
1 101 CYS n 
1 102 GLU n 
1 103 PHE n 
1 104 ILE n 
1 105 GLY n 
1 106 VAL n 
1 107 LEU n 
1 108 VAL n 
1 109 ARG n 
1 110 GLN n 
1 111 CYS n 
1 112 GLN n 
1 113 TYR n 
1 114 SER n 
1 115 ILE n 
1 116 ILE n 
1 117 TYR n 
1 118 ASP n 
1 119 GLU n 
1 120 TYR n 
1 121 MET n 
1 122 MET n 
1 123 ASP n 
1 124 THR n 
1 125 VAL n 
1 126 ILE n 
1 127 SER n 
1 128 LEU n 
1 129 LEU n 
1 130 THR n 
1 131 GLY n 
1 132 LEU n 
1 133 SER n 
1 134 ASP n 
1 135 SER n 
1 136 GLN n 
1 137 VAL n 
1 138 ARG n 
1 139 ALA n 
1 140 PHE n 
1 141 ARG n 
1 142 HIS n 
1 143 THR n 
1 144 SER n 
1 145 THR n 
1 146 LEU n 
1 147 ALA n 
1 148 ALA n 
1 149 MET n 
1 150 LYS n 
1 151 LEU n 
1 152 MET n 
1 153 THR n 
1 154 ALA n 
1 155 LEU n 
1 156 VAL n 
1 157 ASN n 
1 158 VAL n 
1 159 ALA n 
1 160 LEU n 
1 161 ASN n 
1 162 LEU n 
1 163 SER n 
1 164 ILE n 
1 165 ASN n 
1 166 MET n 
1 167 ASP n 
1 168 ASN n 
1 169 THR n 
1 170 GLN n 
1 171 ARG n 
1 172 GLN n 
1 173 TYR n 
1 174 GLU n 
1 175 ALA n 
1 176 GLU n 
1 177 ARG n 
1 178 ASN n 
1 179 LYS n 
1 180 MET n 
1 181 ILE n 
1 182 GLY n 
1 183 LYS n 
1 184 ARG n 
1 185 ALA n 
1 186 ASN n 
1 187 GLU n 
1 188 ARG n 
1 189 LEU n 
1 190 GLU n 
1 191 LEU n 
1 192 LEU n 
1 193 LEU n 
1 194 GLN n 
1 195 LYS n 
1 196 ARG n 
1 197 LYS n 
1 198 GLU n 
1 199 LEU n 
1 200 GLN n 
1 201 GLU n 
1 202 ASN n 
1 203 GLN n 
1 204 ASP n 
1 205 GLU n 
1 206 ILE n 
1 207 GLU n 
1 208 ASN n 
1 209 MET n 
1 210 MET n 
1 211 ASN n 
1 212 ALA n 
1 213 ILE n 
1 214 PHE n 
1 215 LYS n 
1 216 GLY n 
1 217 VAL n 
1 218 PHE n 
1 219 VAL n 
1 220 HIS n 
1 221 ARG n 
1 222 TYR n 
1 223 ARG n 
1 224 ASP n 
1 225 ALA n 
1 226 ILE n 
1 227 ALA n 
1 228 GLU n 
1 229 ILE n 
1 230 ARG n 
1 231 ALA n 
1 232 ILE n 
1 233 CYS n 
1 234 ILE n 
1 235 GLU n 
1 236 GLU n 
1 237 ILE n 
1 238 GLY n 
1 239 ILE n 
1 240 TRP n 
1 241 MET n 
1 242 LYS n 
1 243 MET n 
1 244 TYR n 
1 245 SER n 
1 246 ASP n 
1 247 ALA n 
1 248 PHE n 
1 249 LEU n 
1 250 ASN n 
1 251 ASP n 
1 252 SER n 
1 253 TYR n 
1 254 LEU n 
1 255 LYS n 
1 256 TYR n 
1 257 VAL n 
1 258 GLY n 
1 259 TRP n 
1 260 THR n 
1 261 MET n 
1 262 HIS n 
1 263 ASP n 
1 264 LYS n 
1 265 GLN n 
1 266 GLY n 
1 267 GLU n 
1 268 VAL n 
1 269 ARG n 
1 270 LEU n 
1 271 LYS n 
1 272 CYS n 
1 273 LEU n 
1 274 THR n 
1 275 ALA n 
1 276 LEU n 
1 277 GLN n 
1 278 GLY n 
1 279 LEU n 
1 280 TYR n 
1 281 TYR n 
1 282 ASN n 
1 283 LYS n 
1 284 GLU n 
1 285 LEU n 
1 286 ASN n 
1 287 SER n 
1 288 LYS n 
1 289 LEU n 
1 290 GLU n 
1 291 LEU n 
1 292 PHE n 
1 293 THR n 
1 294 SER n 
1 295 ARG n 
1 296 PHE n 
1 297 LYS n 
1 298 ASP n 
1 299 ARG n 
1 300 ILE n 
1 301 VAL n 
1 302 SER n 
1 303 MET n 
1 304 THR n 
1 305 LEU n 
1 306 ASP n 
1 307 LYS n 
1 308 GLU n 
1 309 TYR n 
1 310 ASP n 
1 311 VAL n 
1 312 ALA n 
1 313 VAL n 
1 314 GLN n 
1 315 ALA n 
1 316 ILE n 
1 317 LYS n 
1 318 LEU n 
1 319 LEU n 
1 320 THR n 
1 321 LEU n 
1 322 VAL n 
1 323 LEU n 
1 324 GLN n 
1 325 SER n 
1 326 SER n 
1 327 GLU n 
1 328 GLU n 
1 329 VAL n 
1 330 LEU n 
1 331 THR n 
1 332 ALA n 
1 333 GLU n 
1 334 ASP n 
1 335 CYS n 
1 336 GLU n 
1 337 ASN n 
1 338 VAL n 
1 339 TYR n 
1 340 HIS n 
1 341 LEU n 
1 342 VAL n 
1 343 TYR n 
1 344 SER n 
1 345 ALA n 
1 346 HIS n 
1 347 ARG n 
1 348 PRO n 
1 349 VAL n 
1 350 ALA n 
1 351 VAL n 
1 352 ALA n 
1 353 ALA n 
1 354 GLY n 
1 355 GLU n 
1 356 PHE n 
1 357 LEU n 
1 358 TYR n 
1 359 LYS n 
1 360 LYS n 
1 361 LEU n 
1 362 PHE n 
1 363 SER n 
1 364 ARG n 
1 365 ARG n 
1 366 ASP n 
1 367 PRO n 
1 368 GLU n 
1 369 GLU n 
1 370 ASP n 
1 371 GLY n 
1 372 LEU n 
1 373 MET n 
1 374 LYS n 
1 375 ARG n 
1 376 ARG n 
1 377 GLY n 
1 378 ARG n 
1 379 GLN n 
1 380 GLY n 
1 381 PRO n 
1 382 ASN n 
1 383 ALA n 
1 384 ASN n 
1 385 LEU n 
1 386 VAL n 
1 387 LYS n 
1 388 THR n 
1 389 LEU n 
1 390 VAL n 
1 391 PHE n 
1 392 PHE n 
1 393 PHE n 
1 394 LEU n 
1 395 GLU n 
1 396 SER n 
1 397 GLU n 
1 398 LEU n 
1 399 HIS n 
1 400 GLU n 
1 401 HIS n 
1 402 ALA n 
1 403 ALA n 
1 404 TYR n 
1 405 LEU n 
1 406 VAL n 
1 407 ASP n 
1 408 SER n 
1 409 MET n 
1 410 TRP n 
1 411 ASP n 
1 412 CYS n 
1 413 ALA n 
1 414 THR n 
1 415 GLU n 
1 416 LEU n 
1 417 LEU n 
1 418 LYS n 
1 419 ASP n 
1 420 TRP n 
1 421 GLU n 
1 422 CYS n 
1 423 MET n 
1 424 ASN n 
1 425 SER n 
1 426 LEU n 
1 427 LEU n 
1 428 LEU n 
1 429 GLU n 
1 430 GLU n 
1 431 PRO n 
1 432 LEU n 
1 433 SER n 
1 434 GLY n 
1 435 GLU n 
1 436 GLU n 
1 437 ALA n 
1 438 LEU n 
1 439 THR n 
1 440 ASP n 
1 441 ARG n 
1 442 GLN n 
1 443 GLU n 
1 444 SER n 
1 445 ALA n 
1 446 LEU n 
1 447 ILE n 
1 448 GLU n 
1 449 ILE n 
1 450 MET n 
1 451 LEU n 
1 452 CYS n 
1 453 THR n 
1 454 ILE n 
1 455 ARG n 
1 456 GLN n 
1 457 ALA n 
1 458 ALA n 
1 459 GLU n 
1 460 CYS n 
1 461 HIS n 
1 462 PRO n 
1 463 PRO n 
1 464 VAL n 
1 465 GLY n 
1 466 ARG n 
1 467 GLY n 
1 468 THR n 
1 469 GLY n 
1 470 LYS n 
1 471 ARG n 
1 472 VAL n 
1 473 LEU n 
1 474 THR n 
1 475 ALA n 
1 476 LYS n 
1 477 GLU n 
1 478 LYS n 
1 479 LYS n 
1 480 THR n 
1 481 GLN n 
1 482 LEU n 
1 483 ASP n 
1 484 ASP n 
1 485 ARG n 
1 486 THR n 
1 487 ARG n 
1 488 ILE n 
1 489 THR n 
1 490 GLU n 
1 491 LEU n 
1 492 PHE n 
1 493 ALA n 
1 494 VAL n 
1 495 ALA n 
1 496 LEU n 
1 497 PRO n 
1 498 GLN n 
1 499 LEU n 
1 500 LEU n 
1 501 ALA n 
1 502 LYS n 
1 503 TYR n 
1 504 SER n 
1 505 VAL n 
1 506 ASP n 
1 507 ALA n 
1 508 GLU n 
1 509 LYS n 
1 510 VAL n 
1 511 THR n 
1 512 ASN n 
1 513 LEU n 
1 514 LEU n 
1 515 GLN n 
1 516 LEU n 
1 517 PRO n 
1 518 GLN n 
1 519 TYR n 
1 520 PHE n 
1 521 ASP n 
1 522 LEU n 
1 523 GLU n 
1 524 ILE n 
1 525 TYR n 
1 526 THR n 
1 527 THR n 
1 528 GLY n 
1 529 ARG n 
1 530 LEU n 
1 531 GLU n 
1 532 LYS n 
1 533 HIS n 
1 534 LEU n 
1 535 ASP n 
1 536 ALA n 
1 537 LEU n 
1 538 LEU n 
1 539 ARG n 
1 540 GLN n 
1 541 ILE n 
1 542 ARG n 
1 543 ASN n 
1 544 ILE n 
1 545 VAL n 
1 546 GLU n 
1 547 LYS n 
1 548 HIS n 
1 549 THR n 
1 550 ASP n 
1 551 THR n 
1 552 ASP n 
1 553 VAL n 
1 554 LEU n 
1 555 GLU n 
1 556 ALA n 
1 557 CYS n 
1 558 SER n 
1 559 LYS n 
1 560 THR n 
1 561 TYR n 
1 562 HIS n 
1 563 ALA n 
1 564 LEU n 
1 565 CYS n 
1 566 ASN n 
1 567 GLU n 
1 568 GLU n 
1 569 PHE n 
1 570 THR n 
1 571 ILE n 
1 572 PHE n 
1 573 ASN n 
1 574 ARG n 
1 575 VAL n 
1 576 ASP n 
1 577 ILE n 
1 578 SER n 
1 579 ARG n 
1 580 SER n 
1 581 GLN n 
1 582 LEU n 
1 583 ILE n 
1 584 ASP n 
1 585 GLU n 
1 586 LEU n 
1 587 ALA n 
1 588 ASP n 
1 589 LYS n 
1 590 PHE n 
1 591 ASN n 
1 592 ARG n 
1 593 LEU n 
1 594 LEU n 
1 595 GLU n 
1 596 ASP n 
1 597 PHE n 
1 598 LEU n 
1 599 GLN n 
1 600 GLU n 
1 601 GLY n 
1 602 GLU n 
1 603 GLU n 
1 604 PRO n 
1 605 ASP n 
1 606 GLU n 
1 607 ASP n 
1 608 ASP n 
1 609 ALA n 
1 610 TYR n 
1 611 GLN n 
1 612 VAL n 
1 613 LEU n 
1 614 SER n 
1 615 THR n 
1 616 LEU n 
1 617 LYS n 
1 618 ARG n 
1 619 ILE n 
1 620 THR n 
1 621 ALA n 
1 622 PHE n 
1 623 HIS n 
1 624 ASN n 
1 625 ALA n 
1 626 HIS n 
1 627 ASP n 
1 628 LEU n 
1 629 SER n 
1 630 LYS n 
1 631 TRP n 
1 632 ASP n 
1 633 LEU n 
1 634 PHE n 
1 635 ALA n 
1 636 CYS n 
1 637 ASN n 
1 638 TYR n 
1 639 LYS n 
1 640 LEU n 
1 641 LEU n 
1 642 LYS n 
1 643 THR n 
1 644 GLY n 
1 645 ILE n 
1 646 GLU n 
1 647 ASN n 
1 648 GLY n 
1 649 ASP n 
1 650 MET n 
1 651 PRO n 
1 652 GLU n 
1 653 GLN n 
1 654 ILE n 
1 655 VAL n 
1 656 ILE n 
1 657 HIS n 
1 658 ALA n 
1 659 LEU n 
1 660 GLN n 
1 661 CYS n 
1 662 ALA n 
1 663 HIS n 
1 664 TYR n 
1 665 VAL n 
1 666 ILE n 
1 667 LEU n 
1 668 TRP n 
1 669 GLN n 
1 670 LEU n 
1 671 ALA n 
1 672 LYS n 
1 673 ILE n 
1 674 THR n 
1 675 GLU n 
1 676 SER n 
1 677 THR n 
1 678 SER n 
1 679 THR n 
1 680 LYS n 
1 681 GLU n 
1 682 ASP n 
1 683 LEU n 
1 684 LEU n 
1 685 ARG n 
1 686 LEU n 
1 687 LYS n 
1 688 LYS n 
1 689 GLN n 
1 690 MET n 
1 691 ARG n 
1 692 VAL n 
1 693 PHE n 
1 694 CYS n 
1 695 GLN n 
1 696 ILE n 
1 697 CYS n 
1 698 GLN n 
1 699 HIS n 
1 700 TYR n 
1 701 LEU n 
1 702 THR n 
1 703 ASN n 
1 704 VAL n 
1 705 ASN n 
1 706 THR n 
1 707 THR n 
1 708 VAL n 
1 709 LYS n 
1 710 GLU n 
1 711 GLN n 
1 712 ALA n 
1 713 PHE n 
1 714 THR n 
1 715 ILE n 
1 716 LEU n 
1 717 CYS n 
1 718 ASP n 
1 719 ILE n 
1 720 LEU n 
1 721 MET n 
1 722 ILE n 
1 723 PHE n 
1 724 SER n 
1 725 HIS n 
1 726 GLN n 
1 727 ILE n 
1 728 MET n 
1 729 SER n 
1 730 GLY n 
1 731 GLY n 
1 732 ARG n 
1 733 ASP n 
1 734 MET n 
1 735 LEU n 
1 736 GLU n 
1 737 PRO n 
1 738 LEU n 
1 739 VAL n 
1 740 TYR n 
1 741 THR n 
1 742 PRO n 
1 743 ASP n 
1 744 SER n 
1 745 SER n 
1 746 LEU n 
1 747 GLN n 
1 748 SER n 
1 749 GLU n 
1 750 LEU n 
1 751 LEU n 
1 752 SER n 
1 753 PHE n 
1 754 ILE n 
1 755 LEU n 
1 756 ASP n 
1 757 HIS n 
1 758 VAL n 
1 759 PHE n 
1 760 ILE n 
1 761 GLU n 
1 762 GLN n 
1 763 ASP n 
1 764 ASP n 
1 765 ASP n 
1 766 SER n 
1 767 ASN n 
1 768 SER n 
1 769 ALA n 
1 770 ASP n 
1 771 GLY n 
1 772 GLN n 
1 773 GLN n 
1 774 GLU n 
1 775 ASP n 
1 776 GLU n 
1 777 ALA n 
1 778 SER n 
1 779 LYS n 
1 780 ILE n 
1 781 GLU n 
1 782 ALA n 
1 783 LEU n 
1 784 HIS n 
1 785 LYS n 
1 786 ARG n 
1 787 ARG n 
1 788 ASN n 
1 789 LEU n 
1 790 LEU n 
1 791 ALA n 
1 792 ALA n 
1 793 PHE n 
1 794 CYS n 
1 795 LYS n 
1 796 LEU n 
1 797 ILE n 
1 798 VAL n 
1 799 TYR n 
1 800 THR n 
1 801 VAL n 
1 802 VAL n 
1 803 GLU n 
1 804 MET n 
1 805 ASN n 
1 806 THR n 
1 807 ALA n 
1 808 ALA n 
1 809 ASP n 
1 810 ILE n 
1 811 PHE n 
1 812 LYS n 
1 813 GLN n 
1 814 TYR n 
1 815 MET n 
1 816 LYS n 
1 817 TYR n 
1 818 TYR n 
1 819 ASN n 
1 820 ASP n 
1 821 TYR n 
1 822 GLY n 
1 823 ASP n 
1 824 ILE n 
1 825 ILE n 
1 826 LYS n 
1 827 GLU n 
1 828 THR n 
1 829 MET n 
1 830 SER n 
1 831 LYS n 
1 832 THR n 
1 833 ARG n 
1 834 GLN n 
1 835 ILE n 
1 836 ASP n 
1 837 LYS n 
1 838 ILE n 
1 839 GLN n 
1 840 CYS n 
1 841 ALA n 
1 842 LYS n 
1 843 THR n 
1 844 LEU n 
1 845 ILE n 
1 846 LEU n 
1 847 SER n 
1 848 LEU n 
1 849 GLN n 
1 850 GLN n 
1 851 LEU n 
1 852 PHE n 
1 853 ASN n 
1 854 GLU n 
1 855 MET n 
1 856 ILE n 
1 857 GLN n 
1 858 GLU n 
1 859 ASN n 
1 860 GLY n 
1 861 TYR n 
1 862 ASN n 
1 863 PHE n 
1 864 ASP n 
1 865 ARG n 
1 866 SER n 
1 867 SER n 
1 868 SER n 
1 869 THR n 
1 870 PHE n 
1 871 SER n 
1 872 GLY n 
1 873 ILE n 
1 874 LYS n 
1 875 GLU n 
1 876 LEU n 
1 877 ALA n 
1 878 ARG n 
1 879 ARG n 
1 880 PHE n 
1 881 ALA n 
1 882 LEU n 
1 883 THR n 
1 884 PHE n 
1 885 GLY n 
1 886 LEU n 
1 887 ASP n 
1 888 GLN n 
1 889 LEU n 
1 890 LYS n 
1 891 THR n 
1 892 ARG n 
1 893 GLU n 
1 894 ALA n 
1 895 ILE n 
1 896 ALA n 
1 897 MET n 
1 898 LEU n 
1 899 HIS n 
1 900 LYS n 
1 901 ASP n 
1 902 GLY n 
1 903 ILE n 
1 904 GLU n 
1 905 PHE n 
1 906 ALA n 
1 907 PHE n 
1 908 LYS n 
1 909 GLU n 
1 910 PRO n 
1 911 ASN n 
1 912 PRO n 
1 913 GLN n 
1 914 GLY n 
1 915 GLU n 
1 916 SER n 
1 917 HIS n 
1 918 PRO n 
1 919 PRO n 
1 920 LEU n 
1 921 ASN n 
1 922 LEU n 
1 923 ALA n 
1 924 PHE n 
1 925 LEU n 
1 926 ASP n 
1 927 ILE n 
1 928 LEU n 
1 929 SER n 
1 930 GLU n 
1 931 PHE n 
1 932 SER n 
1 933 SER n 
1 934 LYS n 
1 935 LEU n 
1 936 LEU n 
1 937 ARG n 
1 938 GLN n 
1 939 ASP n 
1 940 LYS n 
1 941 ARG n 
1 942 THR n 
1 943 VAL n 
1 944 TYR n 
1 945 VAL n 
1 946 TYR n 
1 947 LEU n 
1 948 GLU n 
1 949 LYS n 
1 950 PHE n 
1 951 MET n 
1 952 THR n 
1 953 PHE n 
1 954 GLN n 
1 955 MET n 
1 956 SER n 
1 957 LEU n 
1 958 ARG n 
1 959 ARG n 
1 960 GLU n 
1 961 ASP n 
1 962 VAL n 
1 963 TRP n 
1 964 LEU n 
1 965 PRO n 
1 966 LEU n 
1 967 MET n 
1 968 SER n 
1 969 TYR n 
1 970 ARG n 
1 971 ASN n 
1 972 SER n 
1 973 LEU n 
1 974 LEU n 
1 975 ALA n 
1 976 GLY n 
1 977 GLY n 
1 978 ASP n 
1 979 ASP n 
1 980 ASP n 
1 981 THR n 
1 982 MET n 
1 983 SER n 
1 984 VAL n 
1 985 ILE n 
2 1   GLY n 
2 2   PRO n 
2 3   GLY n 
2 4   SER n 
2 5   ASP n 
2 6   PRO n 
2 7   VAL n 
2 8   GLU n 
2 9   PRO n 
2 10  MET n 
2 11  PRO n 
2 12  THR n 
2 13  MET n 
2 14  THR n 
2 15  ASP n 
2 16  GLN n 
2 17  THR n 
2 18  THR n 
2 19  LEU n 
2 20  VAL n 
2 21  PRO n 
2 22  ASN n 
2 23  GLU n 
2 24  GLU n 
2 25  GLU n 
2 26  ALA n 
2 27  PHE n 
2 28  ALA n 
2 29  LEU n 
2 30  GLU n 
2 31  PRO n 
2 32  ILE n 
2 33  ASP n 
2 34  ILE n 
2 35  THR n 
2 36  VAL n 
2 37  LYS n 
2 38  GLU n 
2 39  THR n 
2 40  LYS n 
2 41  ALA n 
2 42  LYS n 
2 43  ARG n 
2 44  LYS n 
2 45  ARG n 
2 46  LYS n 
2 47  LEU n 
2 48  ILE n 
2 49  VAL n 
2 50  ASP n 
2 51  SER n 
2 52  VAL n 
2 53  LYS n 
2 54  GLU n 
2 55  LEU n 
2 56  ASP n 
2 57  SER n 
2 58  LYS n 
2 59  THR n 
2 60  ILE n 
2 61  ARG n 
2 62  ALA n 
2 63  GLN n 
2 64  LEU n 
2 65  SER n 
2 66  ASP n 
2 67  TYR n 
2 68  SER n 
2 69  ASP n 
2 70  ILE n 
2 71  VAL n 
2 72  THR n 
2 73  THR n 
2 74  LEU n 
2 75  ASP n 
2 76  LEU n 
2 77  ALA n 
2 78  PRO n 
2 79  PRO n 
2 80  THR n 
2 81  LYS n 
2 82  LYS n 
2 83  LEU n 
2 84  MET n 
2 85  MET n 
2 86  TRP n 
2 87  LYS n 
2 88  GLU n 
2 89  THR n 
2 90  GLY n 
2 91  GLY n 
2 92  VAL n 
2 93  GLU n 
2 94  LYS n 
2 95  LEU n 
2 96  PHE n 
2 97  PHE n 
2 98  LEU n 
2 99  PRO n 
2 100 ALA n 
2 101 GLN n 
2 102 PRO n 
2 103 LEU n 
2 104 TRP n 
2 105 ASN n 
2 106 ASN n 
2 107 ARG n 
2 108 LEU n 
2 109 LEU n 
2 110 LYS n 
2 111 LEU n 
2 112 PHE n 
2 113 THR n 
2 114 ARG n 
2 115 CYS n 
2 116 LEU n 
2 117 THR n 
2 118 PRO n 
2 119 LEU n 
2 120 VAL n 
2 121 PRO n 
2 122 GLU n 
2 123 ASP n 
2 124 LEU n 
2 125 ARG n 
2 126 LYS n 
2 127 ARG n 
2 128 ARG n 
2 129 LYS n 
2 130 GLY n 
2 131 GLY n 
2 132 GLU n 
2 133 ALA n 
2 134 ASP n 
2 135 ASN n 
2 136 LEU n 
2 137 ASP n 
2 138 GLU n 
2 139 PHE n 
2 140 LEU n 
2 141 LYS n 
2 142 GLU n 
2 143 PHE n 
3 1   GLY n 
3 2   PRO n 
3 3   GLY n 
3 4   SER n 
3 5   PRO n 
3 6   VAL n 
3 7   LYS n 
3 8   ASP n 
3 9   GLU n 
3 10  TYR n 
3 11  GLU n 
3 12  PHE n 
3 13  ASP n 
3 14  GLU n 
3 15  ASP n 
3 16  ASP n 
3 17  GLU n 
3 18  GLN n 
3 19  ASP n 
3 20  ARG n 
3 21  VAL n 
3 22  PRO n 
3 23  PRO n 
3 24  VAL n 
3 25  ASP n 
3 26  ASP n 
3 27  LYS n 
3 28  HIS n 
3 29  LEU n 
3 30  LEU n 
3 31  LYS n 
3 32  LYS n 
3 33  ASP n 
3 34  TYR n 
3 35  ARG n 
3 36  LYS n 
3 37  GLU n 
3 38  ALA n 
3 39  LYS n 
3 40  ALA n 
3 41  ASN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 985 'house mouse' ? 'Stag2, Sa2, Sap2'  ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 143 'house mouse' ? 'Rad21, Hr21, Scc1' ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 41  'house mouse' ? Ankrd11             ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   76   ?    ?   ?   A . n 
A 1 2   PRO 2   77   ?    ?   ?   A . n 
A 1 3   GLY 3   78   ?    ?   ?   A . n 
A 1 4   SER 4   79   ?    ?   ?   A . n 
A 1 5   GLU 5   80   ?    ?   ?   A . n 
A 1 6   ASN 6   81   ?    ?   ?   A . n 
A 1 7   MET 7   82   ?    ?   ?   A . n 
A 1 8   MET 8   83   83   MET MET A . n 
A 1 9   LEU 9   84   84   LEU LEU A . n 
A 1 10  PHE 10  85   85   PHE PHE A . n 
A 1 11  GLU 11  86   86   GLU GLU A . n 
A 1 12  VAL 12  87   87   VAL VAL A . n 
A 1 13  VAL 13  88   88   VAL VAL A . n 
A 1 14  LYS 14  89   89   LYS LYS A . n 
A 1 15  MET 15  90   90   MET MET A . n 
A 1 16  GLY 16  91   91   GLY GLY A . n 
A 1 17  LYS 17  92   92   LYS LYS A . n 
A 1 18  SER 18  93   93   SER SER A . n 
A 1 19  ALA 19  94   94   ALA ALA A . n 
A 1 20  MET 20  95   95   MET MET A . n 
A 1 21  GLN 21  96   96   GLN GLN A . n 
A 1 22  SER 22  97   97   SER SER A . n 
A 1 23  VAL 23  98   98   VAL VAL A . n 
A 1 24  VAL 24  99   99   VAL VAL A . n 
A 1 25  ASP 25  100  100  ASP ASP A . n 
A 1 26  ASP 26  101  101  ASP ASP A . n 
A 1 27  TRP 27  102  102  TRP TRP A . n 
A 1 28  ILE 28  103  103  ILE ILE A . n 
A 1 29  GLU 29  104  104  GLU GLU A . n 
A 1 30  SER 30  105  105  SER SER A . n 
A 1 31  TYR 31  106  106  TYR TYR A . n 
A 1 32  LYS 32  107  107  LYS LYS A . n 
A 1 33  HIS 33  108  108  HIS HIS A . n 
A 1 34  ASP 34  109  109  ASP ASP A . n 
A 1 35  ARG 35  110  110  ARG ARG A . n 
A 1 36  ASP 36  111  111  ASP ASP A . n 
A 1 37  ILE 37  112  112  ILE ILE A . n 
A 1 38  ALA 38  113  113  ALA ALA A . n 
A 1 39  LEU 39  114  114  LEU LEU A . n 
A 1 40  LEU 40  115  115  LEU LEU A . n 
A 1 41  ASP 41  116  116  ASP ASP A . n 
A 1 42  LEU 42  117  117  LEU LEU A . n 
A 1 43  ILE 43  118  118  ILE ILE A . n 
A 1 44  ASN 44  119  119  ASN ASN A . n 
A 1 45  PHE 45  120  120  PHE PHE A . n 
A 1 46  PHE 46  121  121  PHE PHE A . n 
A 1 47  ILE 47  122  122  ILE ILE A . n 
A 1 48  GLN 48  123  123  GLN GLN A . n 
A 1 49  CYS 49  124  124  CYS CYS A . n 
A 1 50  SER 50  125  125  SER SER A . n 
A 1 51  GLY 51  126  126  GLY GLY A . n 
A 1 52  CYS 52  127  127  CYS CYS A . n 
A 1 53  LYS 53  128  128  LYS LYS A . n 
A 1 54  GLY 54  129  129  GLY GLY A . n 
A 1 55  VAL 55  130  130  VAL VAL A . n 
A 1 56  VAL 56  131  131  VAL VAL A . n 
A 1 57  THR 57  132  132  THR THR A . n 
A 1 58  ALA 58  133  133  ALA ALA A . n 
A 1 59  GLU 59  134  134  GLU GLU A . n 
A 1 60  MET 60  135  135  MET MET A . n 
A 1 61  PHE 61  136  136  PHE PHE A . n 
A 1 62  ARG 62  137  137  ARG ARG A . n 
A 1 63  HIS 63  138  138  HIS HIS A . n 
A 1 64  MET 64  139  139  MET MET A . n 
A 1 65  GLN 65  140  140  GLN GLN A . n 
A 1 66  ASN 66  141  141  ASN ASN A . n 
A 1 67  SER 67  142  142  SER SER A . n 
A 1 68  GLU 68  143  143  GLU GLU A . n 
A 1 69  ILE 69  144  144  ILE ILE A . n 
A 1 70  ILE 70  145  145  ILE ILE A . n 
A 1 71  ARG 71  146  146  ARG ARG A . n 
A 1 72  LYS 72  147  147  LYS LYS A . n 
A 1 73  MET 73  148  148  MET MET A . n 
A 1 74  THR 74  149  149  THR THR A . n 
A 1 75  GLU 75  150  150  GLU GLU A . n 
A 1 76  GLU 76  151  151  GLU GLU A . n 
A 1 77  PHE 77  152  152  PHE PHE A . n 
A 1 78  ASP 78  153  153  ASP ASP A . n 
A 1 79  GLU 79  154  154  GLU GLU A . n 
A 1 80  ASP 80  155  155  ASP ASP A . n 
A 1 81  SER 81  156  156  SER SER A . n 
A 1 82  GLY 82  157  157  GLY GLY A . n 
A 1 83  ASP 83  158  158  ASP ASP A . n 
A 1 84  TYR 84  159  159  TYR TYR A . n 
A 1 85  PRO 85  160  160  PRO PRO A . n 
A 1 86  LEU 86  161  161  LEU LEU A . n 
A 1 87  THR 87  162  162  THR THR A . n 
A 1 88  MET 88  163  163  MET MET A . n 
A 1 89  ALA 89  164  164  ALA ALA A . n 
A 1 90  GLY 90  165  165  GLY GLY A . n 
A 1 91  PRO 91  166  166  PRO PRO A . n 
A 1 92  GLN 92  167  167  GLN GLN A . n 
A 1 93  TRP 93  168  168  TRP TRP A . n 
A 1 94  LYS 94  169  169  LYS LYS A . n 
A 1 95  LYS 95  170  170  LYS LYS A . n 
A 1 96  PHE 96  171  171  PHE PHE A . n 
A 1 97  LYS 97  172  172  LYS LYS A . n 
A 1 98  SER 98  173  173  SER SER A . n 
A 1 99  SER 99  174  174  SER SER A . n 
A 1 100 PHE 100 175  175  PHE PHE A . n 
A 1 101 CYS 101 176  176  CYS CYS A . n 
A 1 102 GLU 102 177  177  GLU GLU A . n 
A 1 103 PHE 103 178  178  PHE PHE A . n 
A 1 104 ILE 104 179  179  ILE ILE A . n 
A 1 105 GLY 105 180  180  GLY GLY A . n 
A 1 106 VAL 106 181  181  VAL VAL A . n 
A 1 107 LEU 107 182  182  LEU LEU A . n 
A 1 108 VAL 108 183  183  VAL VAL A . n 
A 1 109 ARG 109 184  184  ARG ARG A . n 
A 1 110 GLN 110 185  185  GLN GLN A . n 
A 1 111 CYS 111 186  186  CYS CYS A . n 
A 1 112 GLN 112 187  187  GLN GLN A . n 
A 1 113 TYR 113 188  188  TYR TYR A . n 
A 1 114 SER 114 189  189  SER SER A . n 
A 1 115 ILE 115 190  190  ILE ILE A . n 
A 1 116 ILE 116 191  191  ILE ILE A . n 
A 1 117 TYR 117 192  192  TYR TYR A . n 
A 1 118 ASP 118 193  193  ASP ASP A . n 
A 1 119 GLU 119 194  194  GLU GLU A . n 
A 1 120 TYR 120 195  195  TYR TYR A . n 
A 1 121 MET 121 196  196  MET MET A . n 
A 1 122 MET 122 197  197  MET MET A . n 
A 1 123 ASP 123 198  198  ASP ASP A . n 
A 1 124 THR 124 199  199  THR THR A . n 
A 1 125 VAL 125 200  200  VAL VAL A . n 
A 1 126 ILE 126 201  201  ILE ILE A . n 
A 1 127 SER 127 202  202  SER SER A . n 
A 1 128 LEU 128 203  203  LEU LEU A . n 
A 1 129 LEU 129 204  204  LEU LEU A . n 
A 1 130 THR 130 205  205  THR THR A . n 
A 1 131 GLY 131 206  206  GLY GLY A . n 
A 1 132 LEU 132 207  207  LEU LEU A . n 
A 1 133 SER 133 208  208  SER SER A . n 
A 1 134 ASP 134 209  209  ASP ASP A . n 
A 1 135 SER 135 210  210  SER SER A . n 
A 1 136 GLN 136 211  211  GLN GLN A . n 
A 1 137 VAL 137 212  212  VAL VAL A . n 
A 1 138 ARG 138 213  213  ARG ARG A . n 
A 1 139 ALA 139 214  214  ALA ALA A . n 
A 1 140 PHE 140 215  215  PHE PHE A . n 
A 1 141 ARG 141 216  216  ARG ARG A . n 
A 1 142 HIS 142 217  217  HIS HIS A . n 
A 1 143 THR 143 218  218  THR THR A . n 
A 1 144 SER 144 219  219  SER SER A . n 
A 1 145 THR 145 220  220  THR THR A . n 
A 1 146 LEU 146 221  221  LEU LEU A . n 
A 1 147 ALA 147 222  222  ALA ALA A . n 
A 1 148 ALA 148 223  223  ALA ALA A . n 
A 1 149 MET 149 224  224  MET MET A . n 
A 1 150 LYS 150 225  225  LYS LYS A . n 
A 1 151 LEU 151 226  226  LEU LEU A . n 
A 1 152 MET 152 227  227  MET MET A . n 
A 1 153 THR 153 228  228  THR THR A . n 
A 1 154 ALA 154 229  229  ALA ALA A . n 
A 1 155 LEU 155 230  230  LEU LEU A . n 
A 1 156 VAL 156 231  231  VAL VAL A . n 
A 1 157 ASN 157 232  232  ASN ASN A . n 
A 1 158 VAL 158 233  233  VAL VAL A . n 
A 1 159 ALA 159 234  234  ALA ALA A . n 
A 1 160 LEU 160 235  235  LEU LEU A . n 
A 1 161 ASN 161 236  236  ASN ASN A . n 
A 1 162 LEU 162 237  237  LEU LEU A . n 
A 1 163 SER 163 238  238  SER SER A . n 
A 1 164 ILE 164 239  239  ILE ILE A . n 
A 1 165 ASN 165 240  240  ASN ASN A . n 
A 1 166 MET 166 241  241  MET MET A . n 
A 1 167 ASP 167 242  242  ASP ASP A . n 
A 1 168 ASN 168 243  243  ASN ASN A . n 
A 1 169 THR 169 244  244  THR THR A . n 
A 1 170 GLN 170 245  245  GLN GLN A . n 
A 1 171 ARG 171 246  246  ARG ARG A . n 
A 1 172 GLN 172 247  247  GLN GLN A . n 
A 1 173 TYR 173 248  248  TYR TYR A . n 
A 1 174 GLU 174 249  249  GLU GLU A . n 
A 1 175 ALA 175 250  250  ALA ALA A . n 
A 1 176 GLU 176 251  251  GLU GLU A . n 
A 1 177 ARG 177 252  252  ARG ARG A . n 
A 1 178 ASN 178 253  253  ASN ASN A . n 
A 1 179 LYS 179 254  254  LYS LYS A . n 
A 1 180 MET 180 255  ?    ?   ?   A . n 
A 1 181 ILE 181 256  ?    ?   ?   A . n 
A 1 182 GLY 182 257  ?    ?   ?   A . n 
A 1 183 LYS 183 258  ?    ?   ?   A . n 
A 1 184 ARG 184 259  ?    ?   ?   A . n 
A 1 185 ALA 185 260  ?    ?   ?   A . n 
A 1 186 ASN 186 261  261  ASN ASN A . n 
A 1 187 GLU 187 262  262  GLU GLU A . n 
A 1 188 ARG 188 263  263  ARG ARG A . n 
A 1 189 LEU 189 264  264  LEU LEU A . n 
A 1 190 GLU 190 265  265  GLU GLU A . n 
A 1 191 LEU 191 266  266  LEU LEU A . n 
A 1 192 LEU 192 267  267  LEU LEU A . n 
A 1 193 LEU 193 268  268  LEU LEU A . n 
A 1 194 GLN 194 269  269  GLN GLN A . n 
A 1 195 LYS 195 270  270  LYS LYS A . n 
A 1 196 ARG 196 271  271  ARG ARG A . n 
A 1 197 LYS 197 272  272  LYS LYS A . n 
A 1 198 GLU 198 273  273  GLU GLU A . n 
A 1 199 LEU 199 274  274  LEU LEU A . n 
A 1 200 GLN 200 275  275  GLN GLN A . n 
A 1 201 GLU 201 276  276  GLU GLU A . n 
A 1 202 ASN 202 277  277  ASN ASN A . n 
A 1 203 GLN 203 278  278  GLN GLN A . n 
A 1 204 ASP 204 279  279  ASP ASP A . n 
A 1 205 GLU 205 280  280  GLU GLU A . n 
A 1 206 ILE 206 281  281  ILE ILE A . n 
A 1 207 GLU 207 282  282  GLU GLU A . n 
A 1 208 ASN 208 283  283  ASN ASN A . n 
A 1 209 MET 209 284  284  MET MET A . n 
A 1 210 MET 210 285  285  MET MET A . n 
A 1 211 ASN 211 286  286  ASN ASN A . n 
A 1 212 ALA 212 287  287  ALA ALA A . n 
A 1 213 ILE 213 288  288  ILE ILE A . n 
A 1 214 PHE 214 289  289  PHE PHE A . n 
A 1 215 LYS 215 290  290  LYS LYS A . n 
A 1 216 GLY 216 291  291  GLY GLY A . n 
A 1 217 VAL 217 292  292  VAL VAL A . n 
A 1 218 PHE 218 293  293  PHE PHE A . n 
A 1 219 VAL 219 294  294  VAL VAL A . n 
A 1 220 HIS 220 295  295  HIS HIS A . n 
A 1 221 ARG 221 296  296  ARG ARG A . n 
A 1 222 TYR 222 297  297  TYR TYR A . n 
A 1 223 ARG 223 298  298  ARG ARG A . n 
A 1 224 ASP 224 299  299  ASP ASP A . n 
A 1 225 ALA 225 300  300  ALA ALA A . n 
A 1 226 ILE 226 301  301  ILE ILE A . n 
A 1 227 ALA 227 302  302  ALA ALA A . n 
A 1 228 GLU 228 303  303  GLU GLU A . n 
A 1 229 ILE 229 304  304  ILE ILE A . n 
A 1 230 ARG 230 305  305  ARG ARG A . n 
A 1 231 ALA 231 306  306  ALA ALA A . n 
A 1 232 ILE 232 307  307  ILE ILE A . n 
A 1 233 CYS 233 308  308  CYS CYS A . n 
A 1 234 ILE 234 309  309  ILE ILE A . n 
A 1 235 GLU 235 310  310  GLU GLU A . n 
A 1 236 GLU 236 311  311  GLU GLU A . n 
A 1 237 ILE 237 312  312  ILE ILE A . n 
A 1 238 GLY 238 313  313  GLY GLY A . n 
A 1 239 ILE 239 314  314  ILE ILE A . n 
A 1 240 TRP 240 315  315  TRP TRP A . n 
A 1 241 MET 241 316  316  MET MET A . n 
A 1 242 LYS 242 317  317  LYS LYS A . n 
A 1 243 MET 243 318  318  MET MET A . n 
A 1 244 TYR 244 319  319  TYR TYR A . n 
A 1 245 SER 245 320  320  SER SER A . n 
A 1 246 ASP 246 321  321  ASP ASP A . n 
A 1 247 ALA 247 322  322  ALA ALA A . n 
A 1 248 PHE 248 323  323  PHE PHE A . n 
A 1 249 LEU 249 324  324  LEU LEU A . n 
A 1 250 ASN 250 325  325  ASN ASN A . n 
A 1 251 ASP 251 326  326  ASP ASP A . n 
A 1 252 SER 252 327  327  SER SER A . n 
A 1 253 TYR 253 328  328  TYR TYR A . n 
A 1 254 LEU 254 329  329  LEU LEU A . n 
A 1 255 LYS 255 330  330  LYS LYS A . n 
A 1 256 TYR 256 331  331  TYR TYR A . n 
A 1 257 VAL 257 332  332  VAL VAL A . n 
A 1 258 GLY 258 333  333  GLY GLY A . n 
A 1 259 TRP 259 334  334  TRP TRP A . n 
A 1 260 THR 260 335  335  THR THR A . n 
A 1 261 MET 261 336  336  MET MET A . n 
A 1 262 HIS 262 337  337  HIS HIS A . n 
A 1 263 ASP 263 338  338  ASP ASP A . n 
A 1 264 LYS 264 339  339  LYS LYS A . n 
A 1 265 GLN 265 340  340  GLN GLN A . n 
A 1 266 GLY 266 341  341  GLY GLY A . n 
A 1 267 GLU 267 342  342  GLU GLU A . n 
A 1 268 VAL 268 343  343  VAL VAL A . n 
A 1 269 ARG 269 344  344  ARG ARG A . n 
A 1 270 LEU 270 345  345  LEU LEU A . n 
A 1 271 LYS 271 346  346  LYS LYS A . n 
A 1 272 CYS 272 347  347  CYS CYS A . n 
A 1 273 LEU 273 348  348  LEU LEU A . n 
A 1 274 THR 274 349  349  THR THR A . n 
A 1 275 ALA 275 350  350  ALA ALA A . n 
A 1 276 LEU 276 351  351  LEU LEU A . n 
A 1 277 GLN 277 352  352  GLN GLN A . n 
A 1 278 GLY 278 353  353  GLY GLY A . n 
A 1 279 LEU 279 354  354  LEU LEU A . n 
A 1 280 TYR 280 355  355  TYR TYR A . n 
A 1 281 TYR 281 356  356  TYR TYR A . n 
A 1 282 ASN 282 357  357  ASN ASN A . n 
A 1 283 LYS 283 358  358  LYS LYS A . n 
A 1 284 GLU 284 359  359  GLU GLU A . n 
A 1 285 LEU 285 360  360  LEU LEU A . n 
A 1 286 ASN 286 361  361  ASN ASN A . n 
A 1 287 SER 287 362  362  SER SER A . n 
A 1 288 LYS 288 363  363  LYS LYS A . n 
A 1 289 LEU 289 364  364  LEU LEU A . n 
A 1 290 GLU 290 365  365  GLU GLU A . n 
A 1 291 LEU 291 366  366  LEU LEU A . n 
A 1 292 PHE 292 367  367  PHE PHE A . n 
A 1 293 THR 293 368  368  THR THR A . n 
A 1 294 SER 294 369  369  SER SER A . n 
A 1 295 ARG 295 370  370  ARG ARG A . n 
A 1 296 PHE 296 371  371  PHE PHE A . n 
A 1 297 LYS 297 372  372  LYS LYS A . n 
A 1 298 ASP 298 373  373  ASP ASP A . n 
A 1 299 ARG 299 374  374  ARG ARG A . n 
A 1 300 ILE 300 375  375  ILE ILE A . n 
A 1 301 VAL 301 376  376  VAL VAL A . n 
A 1 302 SER 302 377  377  SER SER A . n 
A 1 303 MET 303 378  378  MET MET A . n 
A 1 304 THR 304 379  379  THR THR A . n 
A 1 305 LEU 305 380  380  LEU LEU A . n 
A 1 306 ASP 306 381  381  ASP ASP A . n 
A 1 307 LYS 307 382  382  LYS LYS A . n 
A 1 308 GLU 308 383  383  GLU GLU A . n 
A 1 309 TYR 309 384  384  TYR TYR A . n 
A 1 310 ASP 310 385  385  ASP ASP A . n 
A 1 311 VAL 311 386  386  VAL VAL A . n 
A 1 312 ALA 312 387  387  ALA ALA A . n 
A 1 313 VAL 313 388  388  VAL VAL A . n 
A 1 314 GLN 314 389  389  GLN GLN A . n 
A 1 315 ALA 315 390  390  ALA ALA A . n 
A 1 316 ILE 316 391  391  ILE ILE A . n 
A 1 317 LYS 317 392  392  LYS LYS A . n 
A 1 318 LEU 318 393  393  LEU LEU A . n 
A 1 319 LEU 319 394  394  LEU LEU A . n 
A 1 320 THR 320 395  395  THR THR A . n 
A 1 321 LEU 321 396  396  LEU LEU A . n 
A 1 322 VAL 322 397  397  VAL VAL A . n 
A 1 323 LEU 323 398  398  LEU LEU A . n 
A 1 324 GLN 324 399  399  GLN GLN A . n 
A 1 325 SER 325 400  400  SER SER A . n 
A 1 326 SER 326 401  401  SER SER A . n 
A 1 327 GLU 327 402  402  GLU GLU A . n 
A 1 328 GLU 328 403  403  GLU GLU A . n 
A 1 329 VAL 329 404  404  VAL VAL A . n 
A 1 330 LEU 330 405  405  LEU LEU A . n 
A 1 331 THR 331 406  406  THR THR A . n 
A 1 332 ALA 332 407  407  ALA ALA A . n 
A 1 333 GLU 333 408  408  GLU GLU A . n 
A 1 334 ASP 334 409  409  ASP ASP A . n 
A 1 335 CYS 335 410  410  CYS CYS A . n 
A 1 336 GLU 336 411  411  GLU GLU A . n 
A 1 337 ASN 337 412  412  ASN ASN A . n 
A 1 338 VAL 338 413  413  VAL VAL A . n 
A 1 339 TYR 339 414  414  TYR TYR A . n 
A 1 340 HIS 340 415  415  HIS HIS A . n 
A 1 341 LEU 341 416  416  LEU LEU A . n 
A 1 342 VAL 342 417  417  VAL VAL A . n 
A 1 343 TYR 343 418  418  TYR TYR A . n 
A 1 344 SER 344 419  419  SER SER A . n 
A 1 345 ALA 345 420  420  ALA ALA A . n 
A 1 346 HIS 346 421  421  HIS HIS A . n 
A 1 347 ARG 347 422  422  ARG ARG A . n 
A 1 348 PRO 348 423  423  PRO PRO A . n 
A 1 349 VAL 349 424  424  VAL VAL A . n 
A 1 350 ALA 350 425  425  ALA ALA A . n 
A 1 351 VAL 351 426  426  VAL VAL A . n 
A 1 352 ALA 352 427  427  ALA ALA A . n 
A 1 353 ALA 353 428  428  ALA ALA A . n 
A 1 354 GLY 354 429  429  GLY GLY A . n 
A 1 355 GLU 355 430  430  GLU GLU A . n 
A 1 356 PHE 356 431  431  PHE PHE A . n 
A 1 357 LEU 357 432  432  LEU LEU A . n 
A 1 358 TYR 358 433  433  TYR TYR A . n 
A 1 359 LYS 359 434  434  LYS LYS A . n 
A 1 360 LYS 360 435  435  LYS LYS A . n 
A 1 361 LEU 361 436  436  LEU LEU A . n 
A 1 362 PHE 362 437  437  PHE PHE A . n 
A 1 363 SER 363 438  438  SER SER A . n 
A 1 364 ARG 364 439  439  ARG ARG A . n 
A 1 365 ARG 365 440  440  ARG ARG A . n 
A 1 366 ASP 366 441  ?    ?   ?   A . n 
A 1 367 PRO 367 442  ?    ?   ?   A . n 
A 1 368 GLU 368 443  ?    ?   ?   A . n 
A 1 369 GLU 369 444  ?    ?   ?   A . n 
A 1 370 ASP 370 445  ?    ?   ?   A . n 
A 1 371 GLY 371 446  ?    ?   ?   A . n 
A 1 372 LEU 372 447  ?    ?   ?   A . n 
A 1 373 MET 373 448  ?    ?   ?   A . n 
A 1 374 LYS 374 449  ?    ?   ?   A . n 
A 1 375 ARG 375 450  ?    ?   ?   A . n 
A 1 376 ARG 376 451  ?    ?   ?   A . n 
A 1 377 GLY 377 452  ?    ?   ?   A . n 
A 1 378 ARG 378 453  ?    ?   ?   A . n 
A 1 379 GLN 379 454  ?    ?   ?   A . n 
A 1 380 GLY 380 455  ?    ?   ?   A . n 
A 1 381 PRO 381 456  456  PRO PRO A . n 
A 1 382 ASN 382 457  457  ASN ASN A . n 
A 1 383 ALA 383 458  458  ALA ALA A . n 
A 1 384 ASN 384 459  459  ASN ASN A . n 
A 1 385 LEU 385 460  460  LEU LEU A . n 
A 1 386 VAL 386 461  461  VAL VAL A . n 
A 1 387 LYS 387 462  462  LYS LYS A . n 
A 1 388 THR 388 463  463  THR THR A . n 
A 1 389 LEU 389 464  464  LEU LEU A . n 
A 1 390 VAL 390 465  465  VAL VAL A . n 
A 1 391 PHE 391 466  466  PHE PHE A . n 
A 1 392 PHE 392 467  467  PHE PHE A . n 
A 1 393 PHE 393 468  468  PHE PHE A . n 
A 1 394 LEU 394 469  469  LEU LEU A . n 
A 1 395 GLU 395 470  470  GLU GLU A . n 
A 1 396 SER 396 471  471  SER SER A . n 
A 1 397 GLU 397 472  472  GLU GLU A . n 
A 1 398 LEU 398 473  473  LEU LEU A . n 
A 1 399 HIS 399 474  474  HIS HIS A . n 
A 1 400 GLU 400 475  475  GLU GLU A . n 
A 1 401 HIS 401 476  476  HIS HIS A . n 
A 1 402 ALA 402 477  477  ALA ALA A . n 
A 1 403 ALA 403 478  478  ALA ALA A . n 
A 1 404 TYR 404 479  479  TYR TYR A . n 
A 1 405 LEU 405 480  480  LEU LEU A . n 
A 1 406 VAL 406 481  481  VAL VAL A . n 
A 1 407 ASP 407 482  482  ASP ASP A . n 
A 1 408 SER 408 483  483  SER SER A . n 
A 1 409 MET 409 484  484  MET MET A . n 
A 1 410 TRP 410 485  485  TRP TRP A . n 
A 1 411 ASP 411 486  486  ASP ASP A . n 
A 1 412 CYS 412 487  487  CYS CYS A . n 
A 1 413 ALA 413 488  488  ALA ALA A . n 
A 1 414 THR 414 489  489  THR THR A . n 
A 1 415 GLU 415 490  490  GLU GLU A . n 
A 1 416 LEU 416 491  491  LEU LEU A . n 
A 1 417 LEU 417 492  492  LEU LEU A . n 
A 1 418 LYS 418 493  493  LYS LYS A . n 
A 1 419 ASP 419 494  494  ASP ASP A . n 
A 1 420 TRP 420 495  495  TRP TRP A . n 
A 1 421 GLU 421 496  496  GLU GLU A . n 
A 1 422 CYS 422 497  497  CYS CYS A . n 
A 1 423 MET 423 498  498  MET MET A . n 
A 1 424 ASN 424 499  499  ASN ASN A . n 
A 1 425 SER 425 500  500  SER SER A . n 
A 1 426 LEU 426 501  501  LEU LEU A . n 
A 1 427 LEU 427 502  502  LEU LEU A . n 
A 1 428 LEU 428 503  503  LEU LEU A . n 
A 1 429 GLU 429 504  504  GLU GLU A . n 
A 1 430 GLU 430 505  505  GLU GLU A . n 
A 1 431 PRO 431 506  506  PRO PRO A . n 
A 1 432 LEU 432 507  507  LEU LEU A . n 
A 1 433 SER 433 508  508  SER SER A . n 
A 1 434 GLY 434 509  509  GLY GLY A . n 
A 1 435 GLU 435 510  510  GLU GLU A . n 
A 1 436 GLU 436 511  511  GLU GLU A . n 
A 1 437 ALA 437 512  512  ALA ALA A . n 
A 1 438 LEU 438 513  513  LEU LEU A . n 
A 1 439 THR 439 514  514  THR THR A . n 
A 1 440 ASP 440 515  515  ASP ASP A . n 
A 1 441 ARG 441 516  516  ARG ARG A . n 
A 1 442 GLN 442 517  517  GLN GLN A . n 
A 1 443 GLU 443 518  518  GLU GLU A . n 
A 1 444 SER 444 519  519  SER SER A . n 
A 1 445 ALA 445 520  520  ALA ALA A . n 
A 1 446 LEU 446 521  521  LEU LEU A . n 
A 1 447 ILE 447 522  522  ILE ILE A . n 
A 1 448 GLU 448 523  523  GLU GLU A . n 
A 1 449 ILE 449 524  524  ILE ILE A . n 
A 1 450 MET 450 525  525  MET MET A . n 
A 1 451 LEU 451 526  526  LEU LEU A . n 
A 1 452 CYS 452 527  527  CYS CYS A . n 
A 1 453 THR 453 528  528  THR THR A . n 
A 1 454 ILE 454 529  529  ILE ILE A . n 
A 1 455 ARG 455 530  530  ARG ARG A . n 
A 1 456 GLN 456 531  531  GLN GLN A . n 
A 1 457 ALA 457 532  532  ALA ALA A . n 
A 1 458 ALA 458 533  533  ALA ALA A . n 
A 1 459 GLU 459 534  534  GLU GLU A . n 
A 1 460 CYS 460 535  535  CYS CYS A . n 
A 1 461 HIS 461 536  536  HIS HIS A . n 
A 1 462 PRO 462 537  537  PRO PRO A . n 
A 1 463 PRO 463 538  538  PRO PRO A . n 
A 1 464 VAL 464 539  539  VAL VAL A . n 
A 1 465 GLY 465 540  540  GLY GLY A . n 
A 1 466 ARG 466 541  541  ARG ARG A . n 
A 1 467 GLY 467 542  542  GLY GLY A . n 
A 1 468 THR 468 543  543  THR THR A . n 
A 1 469 GLY 469 544  544  GLY GLY A . n 
A 1 470 LYS 470 545  545  LYS LYS A . n 
A 1 471 ARG 471 546  546  ARG ARG A . n 
A 1 472 VAL 472 547  547  VAL VAL A . n 
A 1 473 LEU 473 548  548  LEU LEU A . n 
A 1 474 THR 474 549  549  THR THR A . n 
A 1 475 ALA 475 550  550  ALA ALA A . n 
A 1 476 LYS 476 551  551  LYS LYS A . n 
A 1 477 GLU 477 552  552  GLU GLU A . n 
A 1 478 LYS 478 553  553  LYS LYS A . n 
A 1 479 LYS 479 554  554  LYS LYS A . n 
A 1 480 THR 480 555  555  THR THR A . n 
A 1 481 GLN 481 556  556  GLN GLN A . n 
A 1 482 LEU 482 557  557  LEU LEU A . n 
A 1 483 ASP 483 558  558  ASP ASP A . n 
A 1 484 ASP 484 559  559  ASP ASP A . n 
A 1 485 ARG 485 560  560  ARG ARG A . n 
A 1 486 THR 486 561  561  THR THR A . n 
A 1 487 ARG 487 562  562  ARG ARG A . n 
A 1 488 ILE 488 563  563  ILE ILE A . n 
A 1 489 THR 489 564  564  THR THR A . n 
A 1 490 GLU 490 565  565  GLU GLU A . n 
A 1 491 LEU 491 566  566  LEU LEU A . n 
A 1 492 PHE 492 567  567  PHE PHE A . n 
A 1 493 ALA 493 568  568  ALA ALA A . n 
A 1 494 VAL 494 569  569  VAL VAL A . n 
A 1 495 ALA 495 570  570  ALA ALA A . n 
A 1 496 LEU 496 571  571  LEU LEU A . n 
A 1 497 PRO 497 572  572  PRO PRO A . n 
A 1 498 GLN 498 573  573  GLN GLN A . n 
A 1 499 LEU 499 574  574  LEU LEU A . n 
A 1 500 LEU 500 575  575  LEU LEU A . n 
A 1 501 ALA 501 576  576  ALA ALA A . n 
A 1 502 LYS 502 577  577  LYS LYS A . n 
A 1 503 TYR 503 578  578  TYR TYR A . n 
A 1 504 SER 504 579  579  SER SER A . n 
A 1 505 VAL 505 580  580  VAL VAL A . n 
A 1 506 ASP 506 581  581  ASP ASP A . n 
A 1 507 ALA 507 582  582  ALA ALA A . n 
A 1 508 GLU 508 583  583  GLU GLU A . n 
A 1 509 LYS 509 584  584  LYS LYS A . n 
A 1 510 VAL 510 585  585  VAL VAL A . n 
A 1 511 THR 511 586  586  THR THR A . n 
A 1 512 ASN 512 587  587  ASN ASN A . n 
A 1 513 LEU 513 588  588  LEU LEU A . n 
A 1 514 LEU 514 589  589  LEU LEU A . n 
A 1 515 GLN 515 590  590  GLN GLN A . n 
A 1 516 LEU 516 591  591  LEU LEU A . n 
A 1 517 PRO 517 592  592  PRO PRO A . n 
A 1 518 GLN 518 593  593  GLN GLN A . n 
A 1 519 TYR 519 594  594  TYR TYR A . n 
A 1 520 PHE 520 595  595  PHE PHE A . n 
A 1 521 ASP 521 596  596  ASP ASP A . n 
A 1 522 LEU 522 597  597  LEU LEU A . n 
A 1 523 GLU 523 598  598  GLU GLU A . n 
A 1 524 ILE 524 599  599  ILE ILE A . n 
A 1 525 TYR 525 600  600  TYR TYR A . n 
A 1 526 THR 526 601  601  THR THR A . n 
A 1 527 THR 527 602  602  THR THR A . n 
A 1 528 GLY 528 603  603  GLY GLY A . n 
A 1 529 ARG 529 604  604  ARG ARG A . n 
A 1 530 LEU 530 605  605  LEU LEU A . n 
A 1 531 GLU 531 606  606  GLU GLU A . n 
A 1 532 LYS 532 607  607  LYS LYS A . n 
A 1 533 HIS 533 608  608  HIS HIS A . n 
A 1 534 LEU 534 609  609  LEU LEU A . n 
A 1 535 ASP 535 610  610  ASP ASP A . n 
A 1 536 ALA 536 611  611  ALA ALA A . n 
A 1 537 LEU 537 612  612  LEU LEU A . n 
A 1 538 LEU 538 613  613  LEU LEU A . n 
A 1 539 ARG 539 614  614  ARG ARG A . n 
A 1 540 GLN 540 615  615  GLN GLN A . n 
A 1 541 ILE 541 616  616  ILE ILE A . n 
A 1 542 ARG 542 617  617  ARG ARG A . n 
A 1 543 ASN 543 618  618  ASN ASN A . n 
A 1 544 ILE 544 619  619  ILE ILE A . n 
A 1 545 VAL 545 620  620  VAL VAL A . n 
A 1 546 GLU 546 621  621  GLU GLU A . n 
A 1 547 LYS 547 622  622  LYS LYS A . n 
A 1 548 HIS 548 623  623  HIS HIS A . n 
A 1 549 THR 549 624  624  THR THR A . n 
A 1 550 ASP 550 625  625  ASP ASP A . n 
A 1 551 THR 551 626  626  THR THR A . n 
A 1 552 ASP 552 627  627  ASP ASP A . n 
A 1 553 VAL 553 628  628  VAL VAL A . n 
A 1 554 LEU 554 629  629  LEU LEU A . n 
A 1 555 GLU 555 630  630  GLU GLU A . n 
A 1 556 ALA 556 631  631  ALA ALA A . n 
A 1 557 CYS 557 632  632  CYS CYS A . n 
A 1 558 SER 558 633  633  SER SER A . n 
A 1 559 LYS 559 634  634  LYS LYS A . n 
A 1 560 THR 560 635  635  THR THR A . n 
A 1 561 TYR 561 636  636  TYR TYR A . n 
A 1 562 HIS 562 637  637  HIS HIS A . n 
A 1 563 ALA 563 638  638  ALA ALA A . n 
A 1 564 LEU 564 639  639  LEU LEU A . n 
A 1 565 CYS 565 640  640  CYS CYS A . n 
A 1 566 ASN 566 641  641  ASN ASN A . n 
A 1 567 GLU 567 642  642  GLU GLU A . n 
A 1 568 GLU 568 643  643  GLU GLU A . n 
A 1 569 PHE 569 644  644  PHE PHE A . n 
A 1 570 THR 570 645  645  THR THR A . n 
A 1 571 ILE 571 646  646  ILE ILE A . n 
A 1 572 PHE 572 647  647  PHE PHE A . n 
A 1 573 ASN 573 648  648  ASN ASN A . n 
A 1 574 ARG 574 649  649  ARG ARG A . n 
A 1 575 VAL 575 650  650  VAL VAL A . n 
A 1 576 ASP 576 651  651  ASP ASP A . n 
A 1 577 ILE 577 652  652  ILE ILE A . n 
A 1 578 SER 578 653  653  SER SER A . n 
A 1 579 ARG 579 654  654  ARG ARG A . n 
A 1 580 SER 580 655  655  SER SER A . n 
A 1 581 GLN 581 656  656  GLN GLN A . n 
A 1 582 LEU 582 657  657  LEU LEU A . n 
A 1 583 ILE 583 658  658  ILE ILE A . n 
A 1 584 ASP 584 659  659  ASP ASP A . n 
A 1 585 GLU 585 660  660  GLU GLU A . n 
A 1 586 LEU 586 661  661  LEU LEU A . n 
A 1 587 ALA 587 662  662  ALA ALA A . n 
A 1 588 ASP 588 663  663  ASP ASP A . n 
A 1 589 LYS 589 664  664  LYS LYS A . n 
A 1 590 PHE 590 665  665  PHE PHE A . n 
A 1 591 ASN 591 666  666  ASN ASN A . n 
A 1 592 ARG 592 667  667  ARG ARG A . n 
A 1 593 LEU 593 668  668  LEU LEU A . n 
A 1 594 LEU 594 669  669  LEU LEU A . n 
A 1 595 GLU 595 670  670  GLU GLU A . n 
A 1 596 ASP 596 671  671  ASP ASP A . n 
A 1 597 PHE 597 672  672  PHE PHE A . n 
A 1 598 LEU 598 673  673  LEU LEU A . n 
A 1 599 GLN 599 674  674  GLN GLN A . n 
A 1 600 GLU 600 675  675  GLU GLU A . n 
A 1 601 GLY 601 676  676  GLY GLY A . n 
A 1 602 GLU 602 677  677  GLU GLU A . n 
A 1 603 GLU 603 678  678  GLU GLU A . n 
A 1 604 PRO 604 679  679  PRO PRO A . n 
A 1 605 ASP 605 680  680  ASP ASP A . n 
A 1 606 GLU 606 681  681  GLU GLU A . n 
A 1 607 ASP 607 682  682  ASP ASP A . n 
A 1 608 ASP 608 683  683  ASP ASP A . n 
A 1 609 ALA 609 684  684  ALA ALA A . n 
A 1 610 TYR 610 685  685  TYR TYR A . n 
A 1 611 GLN 611 686  686  GLN GLN A . n 
A 1 612 VAL 612 687  687  VAL VAL A . n 
A 1 613 LEU 613 688  688  LEU LEU A . n 
A 1 614 SER 614 689  689  SER SER A . n 
A 1 615 THR 615 690  690  THR THR A . n 
A 1 616 LEU 616 691  691  LEU LEU A . n 
A 1 617 LYS 617 692  692  LYS LYS A . n 
A 1 618 ARG 618 693  693  ARG ARG A . n 
A 1 619 ILE 619 694  694  ILE ILE A . n 
A 1 620 THR 620 695  695  THR THR A . n 
A 1 621 ALA 621 696  696  ALA ALA A . n 
A 1 622 PHE 622 697  697  PHE PHE A . n 
A 1 623 HIS 623 698  698  HIS HIS A . n 
A 1 624 ASN 624 699  699  ASN ASN A . n 
A 1 625 ALA 625 700  700  ALA ALA A . n 
A 1 626 HIS 626 701  701  HIS HIS A . n 
A 1 627 ASP 627 702  702  ASP ASP A . n 
A 1 628 LEU 628 703  703  LEU LEU A . n 
A 1 629 SER 629 704  704  SER SER A . n 
A 1 630 LYS 630 705  705  LYS LYS A . n 
A 1 631 TRP 631 706  706  TRP TRP A . n 
A 1 632 ASP 632 707  707  ASP ASP A . n 
A 1 633 LEU 633 708  708  LEU LEU A . n 
A 1 634 PHE 634 709  709  PHE PHE A . n 
A 1 635 ALA 635 710  710  ALA ALA A . n 
A 1 636 CYS 636 711  711  CYS CYS A . n 
A 1 637 ASN 637 712  712  ASN ASN A . n 
A 1 638 TYR 638 713  713  TYR TYR A . n 
A 1 639 LYS 639 714  714  LYS LYS A . n 
A 1 640 LEU 640 715  715  LEU LEU A . n 
A 1 641 LEU 641 716  716  LEU LEU A . n 
A 1 642 LYS 642 717  717  LYS LYS A . n 
A 1 643 THR 643 718  718  THR THR A . n 
A 1 644 GLY 644 719  719  GLY GLY A . n 
A 1 645 ILE 645 720  720  ILE ILE A . n 
A 1 646 GLU 646 721  721  GLU GLU A . n 
A 1 647 ASN 647 722  722  ASN ASN A . n 
A 1 648 GLY 648 723  723  GLY GLY A . n 
A 1 649 ASP 649 724  724  ASP ASP A . n 
A 1 650 MET 650 725  725  MET MET A . n 
A 1 651 PRO 651 726  726  PRO PRO A . n 
A 1 652 GLU 652 727  727  GLU GLU A . n 
A 1 653 GLN 653 728  728  GLN GLN A . n 
A 1 654 ILE 654 729  729  ILE ILE A . n 
A 1 655 VAL 655 730  730  VAL VAL A . n 
A 1 656 ILE 656 731  731  ILE ILE A . n 
A 1 657 HIS 657 732  732  HIS HIS A . n 
A 1 658 ALA 658 733  733  ALA ALA A . n 
A 1 659 LEU 659 734  734  LEU LEU A . n 
A 1 660 GLN 660 735  735  GLN GLN A . n 
A 1 661 CYS 661 736  736  CYS CYS A . n 
A 1 662 ALA 662 737  737  ALA ALA A . n 
A 1 663 HIS 663 738  738  HIS HIS A . n 
A 1 664 TYR 664 739  739  TYR TYR A . n 
A 1 665 VAL 665 740  740  VAL VAL A . n 
A 1 666 ILE 666 741  741  ILE ILE A . n 
A 1 667 LEU 667 742  742  LEU LEU A . n 
A 1 668 TRP 668 743  743  TRP TRP A . n 
A 1 669 GLN 669 744  744  GLN GLN A . n 
A 1 670 LEU 670 745  745  LEU LEU A . n 
A 1 671 ALA 671 746  746  ALA ALA A . n 
A 1 672 LYS 672 747  747  LYS LYS A . n 
A 1 673 ILE 673 748  748  ILE ILE A . n 
A 1 674 THR 674 749  749  THR THR A . n 
A 1 675 GLU 675 750  750  GLU GLU A . n 
A 1 676 SER 676 751  751  SER SER A . n 
A 1 677 THR 677 752  752  THR THR A . n 
A 1 678 SER 678 753  753  SER SER A . n 
A 1 679 THR 679 754  754  THR THR A . n 
A 1 680 LYS 680 755  755  LYS LYS A . n 
A 1 681 GLU 681 756  756  GLU GLU A . n 
A 1 682 ASP 682 757  757  ASP ASP A . n 
A 1 683 LEU 683 758  758  LEU LEU A . n 
A 1 684 LEU 684 759  759  LEU LEU A . n 
A 1 685 ARG 685 760  760  ARG ARG A . n 
A 1 686 LEU 686 761  761  LEU LEU A . n 
A 1 687 LYS 687 762  762  LYS LYS A . n 
A 1 688 LYS 688 763  763  LYS LYS A . n 
A 1 689 GLN 689 764  764  GLN GLN A . n 
A 1 690 MET 690 765  765  MET MET A . n 
A 1 691 ARG 691 766  766  ARG ARG A . n 
A 1 692 VAL 692 767  767  VAL VAL A . n 
A 1 693 PHE 693 768  768  PHE PHE A . n 
A 1 694 CYS 694 769  769  CYS CYS A . n 
A 1 695 GLN 695 770  770  GLN GLN A . n 
A 1 696 ILE 696 771  771  ILE ILE A . n 
A 1 697 CYS 697 772  772  CYS CYS A . n 
A 1 698 GLN 698 773  773  GLN GLN A . n 
A 1 699 HIS 699 774  774  HIS HIS A . n 
A 1 700 TYR 700 775  775  TYR TYR A . n 
A 1 701 LEU 701 776  776  LEU LEU A . n 
A 1 702 THR 702 777  777  THR THR A . n 
A 1 703 ASN 703 778  778  ASN ASN A . n 
A 1 704 VAL 704 779  779  VAL VAL A . n 
A 1 705 ASN 705 780  780  ASN ASN A . n 
A 1 706 THR 706 781  781  THR THR A . n 
A 1 707 THR 707 782  782  THR THR A . n 
A 1 708 VAL 708 783  783  VAL VAL A . n 
A 1 709 LYS 709 784  784  LYS LYS A . n 
A 1 710 GLU 710 785  785  GLU GLU A . n 
A 1 711 GLN 711 786  786  GLN GLN A . n 
A 1 712 ALA 712 787  787  ALA ALA A . n 
A 1 713 PHE 713 788  788  PHE PHE A . n 
A 1 714 THR 714 789  789  THR THR A . n 
A 1 715 ILE 715 790  790  ILE ILE A . n 
A 1 716 LEU 716 791  791  LEU LEU A . n 
A 1 717 CYS 717 792  792  CYS CYS A . n 
A 1 718 ASP 718 793  793  ASP ASP A . n 
A 1 719 ILE 719 794  794  ILE ILE A . n 
A 1 720 LEU 720 795  795  LEU LEU A . n 
A 1 721 MET 721 796  796  MET MET A . n 
A 1 722 ILE 722 797  797  ILE ILE A . n 
A 1 723 PHE 723 798  798  PHE PHE A . n 
A 1 724 SER 724 799  799  SER SER A . n 
A 1 725 HIS 725 800  800  HIS HIS A . n 
A 1 726 GLN 726 801  801  GLN GLN A . n 
A 1 727 ILE 727 802  802  ILE ILE A . n 
A 1 728 MET 728 803  803  MET MET A . n 
A 1 729 SER 729 804  804  SER SER A . n 
A 1 730 GLY 730 805  805  GLY GLY A . n 
A 1 731 GLY 731 806  806  GLY GLY A . n 
A 1 732 ARG 732 807  807  ARG ARG A . n 
A 1 733 ASP 733 808  808  ASP ASP A . n 
A 1 734 MET 734 809  809  MET MET A . n 
A 1 735 LEU 735 810  810  LEU LEU A . n 
A 1 736 GLU 736 811  811  GLU GLU A . n 
A 1 737 PRO 737 812  812  PRO PRO A . n 
A 1 738 LEU 738 813  813  LEU LEU A . n 
A 1 739 VAL 739 814  814  VAL VAL A . n 
A 1 740 TYR 740 815  815  TYR TYR A . n 
A 1 741 THR 741 816  816  THR THR A . n 
A 1 742 PRO 742 817  817  PRO PRO A . n 
A 1 743 ASP 743 818  818  ASP ASP A . n 
A 1 744 SER 744 819  819  SER SER A . n 
A 1 745 SER 745 820  820  SER SER A . n 
A 1 746 LEU 746 821  821  LEU LEU A . n 
A 1 747 GLN 747 822  822  GLN GLN A . n 
A 1 748 SER 748 823  823  SER SER A . n 
A 1 749 GLU 749 824  824  GLU GLU A . n 
A 1 750 LEU 750 825  825  LEU LEU A . n 
A 1 751 LEU 751 826  826  LEU LEU A . n 
A 1 752 SER 752 827  827  SER SER A . n 
A 1 753 PHE 753 828  828  PHE PHE A . n 
A 1 754 ILE 754 829  829  ILE ILE A . n 
A 1 755 LEU 755 830  830  LEU LEU A . n 
A 1 756 ASP 756 831  831  ASP ASP A . n 
A 1 757 HIS 757 832  832  HIS HIS A . n 
A 1 758 VAL 758 833  833  VAL VAL A . n 
A 1 759 PHE 759 834  834  PHE PHE A . n 
A 1 760 ILE 760 835  835  ILE ILE A . n 
A 1 761 GLU 761 836  836  GLU GLU A . n 
A 1 762 GLN 762 837  837  GLN GLN A . n 
A 1 763 ASP 763 838  838  ASP ASP A . n 
A 1 764 ASP 764 839  ?    ?   ?   A . n 
A 1 765 ASP 765 840  ?    ?   ?   A . n 
A 1 766 SER 766 841  ?    ?   ?   A . n 
A 1 767 ASN 767 842  ?    ?   ?   A . n 
A 1 768 SER 768 843  ?    ?   ?   A . n 
A 1 769 ALA 769 844  ?    ?   ?   A . n 
A 1 770 ASP 770 845  ?    ?   ?   A . n 
A 1 771 GLY 771 846  ?    ?   ?   A . n 
A 1 772 GLN 772 847  ?    ?   ?   A . n 
A 1 773 GLN 773 848  ?    ?   ?   A . n 
A 1 774 GLU 774 849  ?    ?   ?   A . n 
A 1 775 ASP 775 850  850  ASP ASP A . n 
A 1 776 GLU 776 851  851  GLU GLU A . n 
A 1 777 ALA 777 852  852  ALA ALA A . n 
A 1 778 SER 778 853  853  SER SER A . n 
A 1 779 LYS 779 854  854  LYS LYS A . n 
A 1 780 ILE 780 855  855  ILE ILE A . n 
A 1 781 GLU 781 856  856  GLU GLU A . n 
A 1 782 ALA 782 857  857  ALA ALA A . n 
A 1 783 LEU 783 858  858  LEU LEU A . n 
A 1 784 HIS 784 859  859  HIS HIS A . n 
A 1 785 LYS 785 860  860  LYS LYS A . n 
A 1 786 ARG 786 861  861  ARG ARG A . n 
A 1 787 ARG 787 862  862  ARG ARG A . n 
A 1 788 ASN 788 863  863  ASN ASN A . n 
A 1 789 LEU 789 864  864  LEU LEU A . n 
A 1 790 LEU 790 865  865  LEU LEU A . n 
A 1 791 ALA 791 866  866  ALA ALA A . n 
A 1 792 ALA 792 867  867  ALA ALA A . n 
A 1 793 PHE 793 868  868  PHE PHE A . n 
A 1 794 CYS 794 869  869  CYS CYS A . n 
A 1 795 LYS 795 870  870  LYS LYS A . n 
A 1 796 LEU 796 871  871  LEU LEU A . n 
A 1 797 ILE 797 872  872  ILE ILE A . n 
A 1 798 VAL 798 873  873  VAL VAL A . n 
A 1 799 TYR 799 874  874  TYR TYR A . n 
A 1 800 THR 800 875  875  THR THR A . n 
A 1 801 VAL 801 876  876  VAL VAL A . n 
A 1 802 VAL 802 877  877  VAL VAL A . n 
A 1 803 GLU 803 878  878  GLU GLU A . n 
A 1 804 MET 804 879  879  MET MET A . n 
A 1 805 ASN 805 880  880  ASN ASN A . n 
A 1 806 THR 806 881  881  THR THR A . n 
A 1 807 ALA 807 882  882  ALA ALA A . n 
A 1 808 ALA 808 883  883  ALA ALA A . n 
A 1 809 ASP 809 884  884  ASP ASP A . n 
A 1 810 ILE 810 885  885  ILE ILE A . n 
A 1 811 PHE 811 886  886  PHE PHE A . n 
A 1 812 LYS 812 887  887  LYS LYS A . n 
A 1 813 GLN 813 888  888  GLN GLN A . n 
A 1 814 TYR 814 889  889  TYR TYR A . n 
A 1 815 MET 815 890  890  MET MET A . n 
A 1 816 LYS 816 891  891  LYS LYS A . n 
A 1 817 TYR 817 892  892  TYR TYR A . n 
A 1 818 TYR 818 893  893  TYR TYR A . n 
A 1 819 ASN 819 894  894  ASN ASN A . n 
A 1 820 ASP 820 895  895  ASP ASP A . n 
A 1 821 TYR 821 896  896  TYR TYR A . n 
A 1 822 GLY 822 897  897  GLY GLY A . n 
A 1 823 ASP 823 898  898  ASP ASP A . n 
A 1 824 ILE 824 899  899  ILE ILE A . n 
A 1 825 ILE 825 900  900  ILE ILE A . n 
A 1 826 LYS 826 901  901  LYS LYS A . n 
A 1 827 GLU 827 902  902  GLU GLU A . n 
A 1 828 THR 828 903  903  THR THR A . n 
A 1 829 MET 829 904  904  MET MET A . n 
A 1 830 SER 830 905  905  SER SER A . n 
A 1 831 LYS 831 906  906  LYS LYS A . n 
A 1 832 THR 832 907  907  THR THR A . n 
A 1 833 ARG 833 908  908  ARG ARG A . n 
A 1 834 GLN 834 909  909  GLN GLN A . n 
A 1 835 ILE 835 910  910  ILE ILE A . n 
A 1 836 ASP 836 911  911  ASP ASP A . n 
A 1 837 LYS 837 912  912  LYS LYS A . n 
A 1 838 ILE 838 913  913  ILE ILE A . n 
A 1 839 GLN 839 914  914  GLN GLN A . n 
A 1 840 CYS 840 915  915  CYS CYS A . n 
A 1 841 ALA 841 916  916  ALA ALA A . n 
A 1 842 LYS 842 917  917  LYS LYS A . n 
A 1 843 THR 843 918  918  THR THR A . n 
A 1 844 LEU 844 919  919  LEU LEU A . n 
A 1 845 ILE 845 920  920  ILE ILE A . n 
A 1 846 LEU 846 921  921  LEU LEU A . n 
A 1 847 SER 847 922  922  SER SER A . n 
A 1 848 LEU 848 923  923  LEU LEU A . n 
A 1 849 GLN 849 924  924  GLN GLN A . n 
A 1 850 GLN 850 925  925  GLN GLN A . n 
A 1 851 LEU 851 926  926  LEU LEU A . n 
A 1 852 PHE 852 927  927  PHE PHE A . n 
A 1 853 ASN 853 928  928  ASN ASN A . n 
A 1 854 GLU 854 929  929  GLU GLU A . n 
A 1 855 MET 855 930  930  MET MET A . n 
A 1 856 ILE 856 931  931  ILE ILE A . n 
A 1 857 GLN 857 932  932  GLN GLN A . n 
A 1 858 GLU 858 933  933  GLU GLU A . n 
A 1 859 ASN 859 934  934  ASN ASN A . n 
A 1 860 GLY 860 935  935  GLY GLY A . n 
A 1 861 TYR 861 936  936  TYR TYR A . n 
A 1 862 ASN 862 937  937  ASN ASN A . n 
A 1 863 PHE 863 938  938  PHE PHE A . n 
A 1 864 ASP 864 939  939  ASP ASP A . n 
A 1 865 ARG 865 940  940  ARG ARG A . n 
A 1 866 SER 866 941  941  SER SER A . n 
A 1 867 SER 867 942  942  SER SER A . n 
A 1 868 SER 868 943  943  SER SER A . n 
A 1 869 THR 869 944  944  THR THR A . n 
A 1 870 PHE 870 945  945  PHE PHE A . n 
A 1 871 SER 871 946  946  SER SER A . n 
A 1 872 GLY 872 947  947  GLY GLY A . n 
A 1 873 ILE 873 948  948  ILE ILE A . n 
A 1 874 LYS 874 949  949  LYS LYS A . n 
A 1 875 GLU 875 950  950  GLU GLU A . n 
A 1 876 LEU 876 951  951  LEU LEU A . n 
A 1 877 ALA 877 952  952  ALA ALA A . n 
A 1 878 ARG 878 953  953  ARG ARG A . n 
A 1 879 ARG 879 954  954  ARG ARG A . n 
A 1 880 PHE 880 955  955  PHE PHE A . n 
A 1 881 ALA 881 956  956  ALA ALA A . n 
A 1 882 LEU 882 957  957  LEU LEU A . n 
A 1 883 THR 883 958  958  THR THR A . n 
A 1 884 PHE 884 959  ?    ?   ?   A . n 
A 1 885 GLY 885 960  ?    ?   ?   A . n 
A 1 886 LEU 886 961  ?    ?   ?   A . n 
A 1 887 ASP 887 962  962  ASP ASP A . n 
A 1 888 GLN 888 963  963  GLN GLN A . n 
A 1 889 LEU 889 964  964  LEU LEU A . n 
A 1 890 LYS 890 965  965  LYS LYS A . n 
A 1 891 THR 891 966  966  THR THR A . n 
A 1 892 ARG 892 967  967  ARG ARG A . n 
A 1 893 GLU 893 968  968  GLU GLU A . n 
A 1 894 ALA 894 969  969  ALA ALA A . n 
A 1 895 ILE 895 970  970  ILE ILE A . n 
A 1 896 ALA 896 971  971  ALA ALA A . n 
A 1 897 MET 897 972  972  MET MET A . n 
A 1 898 LEU 898 973  973  LEU LEU A . n 
A 1 899 HIS 899 974  974  HIS HIS A . n 
A 1 900 LYS 900 975  975  LYS LYS A . n 
A 1 901 ASP 901 976  976  ASP ASP A . n 
A 1 902 GLY 902 977  977  GLY GLY A . n 
A 1 903 ILE 903 978  978  ILE ILE A . n 
A 1 904 GLU 904 979  979  GLU GLU A . n 
A 1 905 PHE 905 980  980  PHE PHE A . n 
A 1 906 ALA 906 981  981  ALA ALA A . n 
A 1 907 PHE 907 982  982  PHE PHE A . n 
A 1 908 LYS 908 983  983  LYS LYS A . n 
A 1 909 GLU 909 984  984  GLU GLU A . n 
A 1 910 PRO 910 985  985  PRO PRO A . n 
A 1 911 ASN 911 986  986  ASN ASN A . n 
A 1 912 PRO 912 987  987  PRO PRO A . n 
A 1 913 GLN 913 988  988  GLN GLN A . n 
A 1 914 GLY 914 989  ?    ?   ?   A . n 
A 1 915 GLU 915 990  ?    ?   ?   A . n 
A 1 916 SER 916 991  ?    ?   ?   A . n 
A 1 917 HIS 917 992  ?    ?   ?   A . n 
A 1 918 PRO 918 993  ?    ?   ?   A . n 
A 1 919 PRO 919 994  994  PRO PRO A . n 
A 1 920 LEU 920 995  995  LEU LEU A . n 
A 1 921 ASN 921 996  996  ASN ASN A . n 
A 1 922 LEU 922 997  997  LEU LEU A . n 
A 1 923 ALA 923 998  998  ALA ALA A . n 
A 1 924 PHE 924 999  999  PHE PHE A . n 
A 1 925 LEU 925 1000 1000 LEU LEU A . n 
A 1 926 ASP 926 1001 1001 ASP ASP A . n 
A 1 927 ILE 927 1002 1002 ILE ILE A . n 
A 1 928 LEU 928 1003 1003 LEU LEU A . n 
A 1 929 SER 929 1004 1004 SER SER A . n 
A 1 930 GLU 930 1005 1005 GLU GLU A . n 
A 1 931 PHE 931 1006 1006 PHE PHE A . n 
A 1 932 SER 932 1007 1007 SER SER A . n 
A 1 933 SER 933 1008 1008 SER SER A . n 
A 1 934 LYS 934 1009 1009 LYS LYS A . n 
A 1 935 LEU 935 1010 1010 LEU LEU A . n 
A 1 936 LEU 936 1011 1011 LEU LEU A . n 
A 1 937 ARG 937 1012 1012 ARG ARG A . n 
A 1 938 GLN 938 1013 1013 GLN GLN A . n 
A 1 939 ASP 939 1014 1014 ASP ASP A . n 
A 1 940 LYS 940 1015 1015 LYS LYS A . n 
A 1 941 ARG 941 1016 1016 ARG ARG A . n 
A 1 942 THR 942 1017 1017 THR THR A . n 
A 1 943 VAL 943 1018 1018 VAL VAL A . n 
A 1 944 TYR 944 1019 1019 TYR TYR A . n 
A 1 945 VAL 945 1020 1020 VAL VAL A . n 
A 1 946 TYR 946 1021 1021 TYR TYR A . n 
A 1 947 LEU 947 1022 1022 LEU LEU A . n 
A 1 948 GLU 948 1023 1023 GLU GLU A . n 
A 1 949 LYS 949 1024 1024 LYS LYS A . n 
A 1 950 PHE 950 1025 1025 PHE PHE A . n 
A 1 951 MET 951 1026 1026 MET MET A . n 
A 1 952 THR 952 1027 1027 THR THR A . n 
A 1 953 PHE 953 1028 1028 PHE PHE A . n 
A 1 954 GLN 954 1029 1029 GLN GLN A . n 
A 1 955 MET 955 1030 1030 MET MET A . n 
A 1 956 SER 956 1031 1031 SER SER A . n 
A 1 957 LEU 957 1032 1032 LEU LEU A . n 
A 1 958 ARG 958 1033 1033 ARG ARG A . n 
A 1 959 ARG 959 1034 1034 ARG ARG A . n 
A 1 960 GLU 960 1035 1035 GLU GLU A . n 
A 1 961 ASP 961 1036 1036 ASP ASP A . n 
A 1 962 VAL 962 1037 1037 VAL ALA A . n 
A 1 963 TRP 963 1038 1038 TRP TRP A . n 
A 1 964 LEU 964 1039 1039 LEU LEU A . n 
A 1 965 PRO 965 1040 1040 PRO PRO A . n 
A 1 966 LEU 966 1041 1041 LEU LEU A . n 
A 1 967 MET 967 1042 1042 MET MET A . n 
A 1 968 SER 968 1043 1043 SER SER A . n 
A 1 969 TYR 969 1044 1044 TYR TYR A . n 
A 1 970 ARG 970 1045 1045 ARG ARG A . n 
A 1 971 ASN 971 1046 1046 ASN ASN A . n 
A 1 972 SER 972 1047 1047 SER SER A . n 
A 1 973 LEU 973 1048 1048 LEU LEU A . n 
A 1 974 LEU 974 1049 ?    ?   ?   A . n 
A 1 975 ALA 975 1050 ?    ?   ?   A . n 
A 1 976 GLY 976 1051 ?    ?   ?   A . n 
A 1 977 GLY 977 1052 ?    ?   ?   A . n 
A 1 978 ASP 978 1053 ?    ?   ?   A . n 
A 1 979 ASP 979 1054 ?    ?   ?   A . n 
A 1 980 ASP 980 1055 ?    ?   ?   A . n 
A 1 981 THR 981 1056 ?    ?   ?   A . n 
A 1 982 MET 982 1057 ?    ?   ?   A . n 
A 1 983 SER 983 1058 ?    ?   ?   A . n 
A 1 984 VAL 984 1059 ?    ?   ?   A . n 
A 1 985 ILE 985 1060 ?    ?   ?   A . n 
B 2 1   GLY 1   278  ?    ?   ?   B . n 
B 2 2   PRO 2   279  ?    ?   ?   B . n 
B 2 3   GLY 3   280  ?    ?   ?   B . n 
B 2 4   SER 4   281  ?    ?   ?   B . n 
B 2 5   ASP 5   282  ?    ?   ?   B . n 
B 2 6   PRO 6   283  ?    ?   ?   B . n 
B 2 7   VAL 7   284  ?    ?   ?   B . n 
B 2 8   GLU 8   285  ?    ?   ?   B . n 
B 2 9   PRO 9   286  ?    ?   ?   B . n 
B 2 10  MET 10  287  ?    ?   ?   B . n 
B 2 11  PRO 11  288  ?    ?   ?   B . n 
B 2 12  THR 12  289  ?    ?   ?   B . n 
B 2 13  MET 13  290  ?    ?   ?   B . n 
B 2 14  THR 14  291  ?    ?   ?   B . n 
B 2 15  ASP 15  292  ?    ?   ?   B . n 
B 2 16  GLN 16  293  ?    ?   ?   B . n 
B 2 17  THR 17  294  ?    ?   ?   B . n 
B 2 18  THR 18  295  ?    ?   ?   B . n 
B 2 19  LEU 19  296  ?    ?   ?   B . n 
B 2 20  VAL 20  297  ?    ?   ?   B . n 
B 2 21  PRO 21  298  ?    ?   ?   B . n 
B 2 22  ASN 22  299  ?    ?   ?   B . n 
B 2 23  GLU 23  300  ?    ?   ?   B . n 
B 2 24  GLU 24  301  ?    ?   ?   B . n 
B 2 25  GLU 25  302  ?    ?   ?   B . n 
B 2 26  ALA 26  303  ?    ?   ?   B . n 
B 2 27  PHE 27  304  ?    ?   ?   B . n 
B 2 28  ALA 28  305  ?    ?   ?   B . n 
B 2 29  LEU 29  306  ?    ?   ?   B . n 
B 2 30  GLU 30  307  ?    ?   ?   B . n 
B 2 31  PRO 31  308  ?    ?   ?   B . n 
B 2 32  ILE 32  309  ?    ?   ?   B . n 
B 2 33  ASP 33  310  ?    ?   ?   B . n 
B 2 34  ILE 34  311  ?    ?   ?   B . n 
B 2 35  THR 35  312  ?    ?   ?   B . n 
B 2 36  VAL 36  313  ?    ?   ?   B . n 
B 2 37  LYS 37  314  ?    ?   ?   B . n 
B 2 38  GLU 38  315  ?    ?   ?   B . n 
B 2 39  THR 39  316  ?    ?   ?   B . n 
B 2 40  LYS 40  317  ?    ?   ?   B . n 
B 2 41  ALA 41  318  ?    ?   ?   B . n 
B 2 42  LYS 42  319  ?    ?   ?   B . n 
B 2 43  ARG 43  320  ?    ?   ?   B . n 
B 2 44  LYS 44  321  321  LYS LYS B . n 
B 2 45  ARG 45  322  322  ARG ARG B . n 
B 2 46  LYS 46  323  323  LYS LYS B . n 
B 2 47  LEU 47  324  324  LEU LEU B . n 
B 2 48  ILE 48  325  325  ILE ILE B . n 
B 2 49  VAL 49  326  326  VAL VAL B . n 
B 2 50  ASP 50  327  327  ASP ASP B . n 
B 2 51  SER 51  328  328  SER SER B . n 
B 2 52  VAL 52  329  329  VAL VAL B . n 
B 2 53  LYS 53  330  330  LYS LYS B . n 
B 2 54  GLU 54  331  331  GLU GLU B . n 
B 2 55  LEU 55  332  332  LEU LEU B . n 
B 2 56  ASP 56  333  333  ASP ASP B . n 
B 2 57  SER 57  334  334  SER SER B . n 
B 2 58  LYS 58  335  335  LYS LYS B . n 
B 2 59  THR 59  336  336  THR THR B . n 
B 2 60  ILE 60  337  337  ILE ILE B . n 
B 2 61  ARG 61  338  338  ARG ARG B . n 
B 2 62  ALA 62  339  339  ALA ALA B . n 
B 2 63  GLN 63  340  340  GLN GLN B . n 
B 2 64  LEU 64  341  341  LEU LEU B . n 
B 2 65  SER 65  342  342  SER SER B . n 
B 2 66  ASP 66  343  343  ASP ASP B . n 
B 2 67  TYR 67  344  344  TYR TYR B . n 
B 2 68  SER 68  345  345  SER SER B . n 
B 2 69  ASP 69  346  346  ASP ASP B . n 
B 2 70  ILE 70  347  347  ILE ILE B . n 
B 2 71  VAL 71  348  348  VAL VAL B . n 
B 2 72  THR 72  349  349  THR THR B . n 
B 2 73  THR 73  350  350  THR THR B . n 
B 2 74  LEU 74  351  351  LEU LEU B . n 
B 2 75  ASP 75  352  352  ASP ASP B . n 
B 2 76  LEU 76  353  353  LEU LEU B . n 
B 2 77  ALA 77  354  354  ALA ALA B . n 
B 2 78  PRO 78  355  355  PRO PRO B . n 
B 2 79  PRO 79  356  356  PRO PRO B . n 
B 2 80  THR 80  357  357  THR THR B . n 
B 2 81  LYS 81  358  358  LYS LYS B . n 
B 2 82  LYS 82  359  359  LYS LYS B . n 
B 2 83  LEU 83  360  360  LEU LEU B . n 
B 2 84  MET 84  361  361  MET MET B . n 
B 2 85  MET 85  362  362  MET MET B . n 
B 2 86  TRP 86  363  363  TRP TRP B . n 
B 2 87  LYS 87  364  364  LYS LYS B . n 
B 2 88  GLU 88  365  365  GLU GLU B . n 
B 2 89  THR 89  366  366  THR THR B . n 
B 2 90  GLY 90  367  367  GLY GLY B . n 
B 2 91  GLY 91  368  368  GLY GLY B . n 
B 2 92  VAL 92  369  369  VAL VAL B . n 
B 2 93  GLU 93  370  370  GLU GLU B . n 
B 2 94  LYS 94  371  371  LYS LYS B . n 
B 2 95  LEU 95  372  372  LEU LEU B . n 
B 2 96  PHE 96  373  373  PHE PHE B . n 
B 2 97  PHE 97  374  374  PHE PHE B . n 
B 2 98  LEU 98  375  375  LEU LEU B . n 
B 2 99  PRO 99  376  376  PRO PRO B . n 
B 2 100 ALA 100 377  377  ALA ALA B . n 
B 2 101 GLN 101 378  378  GLN GLN B . n 
B 2 102 PRO 102 379  379  PRO PRO B . n 
B 2 103 LEU 103 380  380  LEU LEU B . n 
B 2 104 TRP 104 381  381  TRP TRP B . n 
B 2 105 ASN 105 382  382  ASN ASN B . n 
B 2 106 ASN 106 383  383  ASN ASN B . n 
B 2 107 ARG 107 384  384  ARG ARG B . n 
B 2 108 LEU 108 385  385  LEU LEU B . n 
B 2 109 LEU 109 386  386  LEU LEU B . n 
B 2 110 LYS 110 387  387  LYS LYS B . n 
B 2 111 LEU 111 388  388  LEU LEU B . n 
B 2 112 PHE 112 389  389  PHE PHE B . n 
B 2 113 THR 113 390  390  THR THR B . n 
B 2 114 ARG 114 391  391  ARG ARG B . n 
B 2 115 CYS 115 392  392  CYS CYS B . n 
B 2 116 LEU 116 393  393  LEU LEU B . n 
B 2 117 THR 117 394  394  THR THR B . n 
B 2 118 PRO 118 395  ?    ?   ?   B . n 
B 2 119 LEU 119 396  ?    ?   ?   B . n 
B 2 120 VAL 120 397  ?    ?   ?   B . n 
B 2 121 PRO 121 398  ?    ?   ?   B . n 
B 2 122 GLU 122 399  ?    ?   ?   B . n 
B 2 123 ASP 123 400  ?    ?   ?   B . n 
B 2 124 LEU 124 401  ?    ?   ?   B . n 
B 2 125 ARG 125 402  ?    ?   ?   B . n 
B 2 126 LYS 126 403  ?    ?   ?   B . n 
B 2 127 ARG 127 404  ?    ?   ?   B . n 
B 2 128 ARG 128 405  ?    ?   ?   B . n 
B 2 129 LYS 129 406  ?    ?   ?   B . n 
B 2 130 GLY 130 407  ?    ?   ?   B . n 
B 2 131 GLY 131 408  ?    ?   ?   B . n 
B 2 132 GLU 132 409  ?    ?   ?   B . n 
B 2 133 ALA 133 410  ?    ?   ?   B . n 
B 2 134 ASP 134 411  ?    ?   ?   B . n 
B 2 135 ASN 135 412  ?    ?   ?   B . n 
B 2 136 LEU 136 413  ?    ?   ?   B . n 
B 2 137 ASP 137 414  ?    ?   ?   B . n 
B 2 138 GLU 138 415  ?    ?   ?   B . n 
B 2 139 PHE 139 416  ?    ?   ?   B . n 
B 2 140 LEU 140 417  ?    ?   ?   B . n 
B 2 141 LYS 141 418  ?    ?   ?   B . n 
B 2 142 GLU 142 419  ?    ?   ?   B . n 
B 2 143 PHE 143 420  ?    ?   ?   B . n 
C 3 1   GLY 1   217  ?    ?   ?   C . n 
C 3 2   PRO 2   218  ?    ?   ?   C . n 
C 3 3   GLY 3   219  ?    ?   ?   C . n 
C 3 4   SER 4   220  ?    ?   ?   C . n 
C 3 5   PRO 5   221  ?    ?   ?   C . n 
C 3 6   VAL 6   222  ?    ?   ?   C . n 
C 3 7   LYS 7   223  ?    ?   ?   C . n 
C 3 8   ASP 8   224  224  ASP ASP C . n 
C 3 9   GLU 9   225  225  GLU GLU C . n 
C 3 10  TYR 10  226  226  TYR TYR C . n 
C 3 11  GLU 11  227  227  GLU GLU C . n 
C 3 12  PHE 12  228  228  PHE PHE C . n 
C 3 13  ASP 13  229  229  ASP ASP C . n 
C 3 14  GLU 14  230  230  GLU GLU C . n 
C 3 15  ASP 15  231  231  ASP ASP C . n 
C 3 16  ASP 16  232  232  ASP ASP C . n 
C 3 17  GLU 17  233  233  GLU GLU C . n 
C 3 18  GLN 18  234  234  GLN GLN C . n 
C 3 19  ASP 19  235  235  ASP ASP C . n 
C 3 20  ARG 20  236  236  ARG ARG C . n 
C 3 21  VAL 21  237  237  VAL VAL C . n 
C 3 22  PRO 22  238  238  PRO PRO C . n 
C 3 23  PRO 23  239  239  PRO PRO C . n 
C 3 24  VAL 24  240  240  VAL VAL C . n 
C 3 25  ASP 25  241  241  ASP ASP C . n 
C 3 26  ASP 26  242  242  ASP ASP C . n 
C 3 27  LYS 27  243  243  LYS LYS C . n 
C 3 28  HIS 28  244  244  HIS HIS C . n 
C 3 29  LEU 29  245  245  LEU LEU C . n 
C 3 30  LEU 30  246  246  LEU LEU C . n 
C 3 31  LYS 31  247  247  LYS LYS C . n 
C 3 32  LYS 32  248  ?    ?   ?   C . n 
C 3 33  ASP 33  249  ?    ?   ?   C . n 
C 3 34  TYR 34  250  ?    ?   ?   C . n 
C 3 35  ARG 35  251  ?    ?   ?   C . n 
C 3 36  LYS 36  252  ?    ?   ?   C . n 
C 3 37  GLU 37  253  ?    ?   ?   C . n 
C 3 38  ALA 38  254  ?    ?   ?   C . n 
C 3 39  LYS 39  255  ?    ?   ?   C . n 
C 3 40  ALA 40  256  ?    ?   ?   C . n 
C 3 41  ASN 41  257  ?    ?   ?   C . n 
D 1 1   GLY 1   76   ?    ?   ?   D . n 
D 1 2   PRO 2   77   ?    ?   ?   D . n 
D 1 3   GLY 3   78   ?    ?   ?   D . n 
D 1 4   SER 4   79   ?    ?   ?   D . n 
D 1 5   GLU 5   80   ?    ?   ?   D . n 
D 1 6   ASN 6   81   ?    ?   ?   D . n 
D 1 7   MET 7   82   82   MET MET D . n 
D 1 8   MET 8   83   83   MET MET D . n 
D 1 9   LEU 9   84   84   LEU LEU D . n 
D 1 10  PHE 10  85   85   PHE PHE D . n 
D 1 11  GLU 11  86   86   GLU GLU D . n 
D 1 12  VAL 12  87   87   VAL VAL D . n 
D 1 13  VAL 13  88   88   VAL VAL D . n 
D 1 14  LYS 14  89   89   LYS LYS D . n 
D 1 15  MET 15  90   90   MET MET D . n 
D 1 16  GLY 16  91   91   GLY GLY D . n 
D 1 17  LYS 17  92   92   LYS LYS D . n 
D 1 18  SER 18  93   93   SER SER D . n 
D 1 19  ALA 19  94   94   ALA ALA D . n 
D 1 20  MET 20  95   95   MET MET D . n 
D 1 21  GLN 21  96   96   GLN GLN D . n 
D 1 22  SER 22  97   97   SER SER D . n 
D 1 23  VAL 23  98   98   VAL VAL D . n 
D 1 24  VAL 24  99   99   VAL VAL D . n 
D 1 25  ASP 25  100  100  ASP ASP D . n 
D 1 26  ASP 26  101  101  ASP ASP D . n 
D 1 27  TRP 27  102  102  TRP TRP D . n 
D 1 28  ILE 28  103  103  ILE ILE D . n 
D 1 29  GLU 29  104  104  GLU GLU D . n 
D 1 30  SER 30  105  105  SER SER D . n 
D 1 31  TYR 31  106  106  TYR TYR D . n 
D 1 32  LYS 32  107  107  LYS LYS D . n 
D 1 33  HIS 33  108  108  HIS HIS D . n 
D 1 34  ASP 34  109  109  ASP ASP D . n 
D 1 35  ARG 35  110  110  ARG ARG D . n 
D 1 36  ASP 36  111  111  ASP ASP D . n 
D 1 37  ILE 37  112  112  ILE ILE D . n 
D 1 38  ALA 38  113  113  ALA ALA D . n 
D 1 39  LEU 39  114  114  LEU LEU D . n 
D 1 40  LEU 40  115  115  LEU LEU D . n 
D 1 41  ASP 41  116  116  ASP ASP D . n 
D 1 42  LEU 42  117  117  LEU LEU D . n 
D 1 43  ILE 43  118  118  ILE ILE D . n 
D 1 44  ASN 44  119  119  ASN ASN D . n 
D 1 45  PHE 45  120  120  PHE PHE D . n 
D 1 46  PHE 46  121  121  PHE PHE D . n 
D 1 47  ILE 47  122  122  ILE ILE D . n 
D 1 48  GLN 48  123  123  GLN GLN D . n 
D 1 49  CYS 49  124  124  CYS CYS D . n 
D 1 50  SER 50  125  125  SER SER D . n 
D 1 51  GLY 51  126  126  GLY GLY D . n 
D 1 52  CYS 52  127  127  CYS CYS D . n 
D 1 53  LYS 53  128  128  LYS LYS D . n 
D 1 54  GLY 54  129  129  GLY GLY D . n 
D 1 55  VAL 55  130  130  VAL VAL D . n 
D 1 56  VAL 56  131  131  VAL VAL D . n 
D 1 57  THR 57  132  132  THR THR D . n 
D 1 58  ALA 58  133  133  ALA ALA D . n 
D 1 59  GLU 59  134  134  GLU GLU D . n 
D 1 60  MET 60  135  135  MET MET D . n 
D 1 61  PHE 61  136  136  PHE PHE D . n 
D 1 62  ARG 62  137  137  ARG ARG D . n 
D 1 63  HIS 63  138  138  HIS HIS D . n 
D 1 64  MET 64  139  139  MET MET D . n 
D 1 65  GLN 65  140  140  GLN GLN D . n 
D 1 66  ASN 66  141  141  ASN ASN D . n 
D 1 67  SER 67  142  142  SER SER D . n 
D 1 68  GLU 68  143  143  GLU GLU D . n 
D 1 69  ILE 69  144  144  ILE ILE D . n 
D 1 70  ILE 70  145  145  ILE ILE D . n 
D 1 71  ARG 71  146  146  ARG ARG D . n 
D 1 72  LYS 72  147  147  LYS LYS D . n 
D 1 73  MET 73  148  148  MET MET D . n 
D 1 74  THR 74  149  149  THR THR D . n 
D 1 75  GLU 75  150  150  GLU GLU D . n 
D 1 76  GLU 76  151  151  GLU GLU D . n 
D 1 77  PHE 77  152  152  PHE PHE D . n 
D 1 78  ASP 78  153  153  ASP ASP D . n 
D 1 79  GLU 79  154  154  GLU GLU D . n 
D 1 80  ASP 80  155  155  ASP ASP D . n 
D 1 81  SER 81  156  156  SER SER D . n 
D 1 82  GLY 82  157  157  GLY GLY D . n 
D 1 83  ASP 83  158  158  ASP ASP D . n 
D 1 84  TYR 84  159  159  TYR TYR D . n 
D 1 85  PRO 85  160  160  PRO PRO D . n 
D 1 86  LEU 86  161  161  LEU LEU D . n 
D 1 87  THR 87  162  162  THR THR D . n 
D 1 88  MET 88  163  163  MET MET D . n 
D 1 89  ALA 89  164  164  ALA ALA D . n 
D 1 90  GLY 90  165  165  GLY GLY D . n 
D 1 91  PRO 91  166  166  PRO PRO D . n 
D 1 92  GLN 92  167  167  GLN GLN D . n 
D 1 93  TRP 93  168  168  TRP TRP D . n 
D 1 94  LYS 94  169  169  LYS LYS D . n 
D 1 95  LYS 95  170  170  LYS LYS D . n 
D 1 96  PHE 96  171  171  PHE PHE D . n 
D 1 97  LYS 97  172  172  LYS LYS D . n 
D 1 98  SER 98  173  173  SER SER D . n 
D 1 99  SER 99  174  174  SER SER D . n 
D 1 100 PHE 100 175  175  PHE PHE D . n 
D 1 101 CYS 101 176  176  CYS CYS D . n 
D 1 102 GLU 102 177  177  GLU GLU D . n 
D 1 103 PHE 103 178  178  PHE PHE D . n 
D 1 104 ILE 104 179  179  ILE ILE D . n 
D 1 105 GLY 105 180  180  GLY GLY D . n 
D 1 106 VAL 106 181  181  VAL VAL D . n 
D 1 107 LEU 107 182  182  LEU LEU D . n 
D 1 108 VAL 108 183  183  VAL VAL D . n 
D 1 109 ARG 109 184  184  ARG ARG D . n 
D 1 110 GLN 110 185  185  GLN GLN D . n 
D 1 111 CYS 111 186  186  CYS CYS D . n 
D 1 112 GLN 112 187  187  GLN GLN D . n 
D 1 113 TYR 113 188  188  TYR TYR D . n 
D 1 114 SER 114 189  189  SER SER D . n 
D 1 115 ILE 115 190  190  ILE ILE D . n 
D 1 116 ILE 116 191  191  ILE ILE D . n 
D 1 117 TYR 117 192  192  TYR TYR D . n 
D 1 118 ASP 118 193  193  ASP ASP D . n 
D 1 119 GLU 119 194  194  GLU GLU D . n 
D 1 120 TYR 120 195  195  TYR TYR D . n 
D 1 121 MET 121 196  196  MET MET D . n 
D 1 122 MET 122 197  197  MET MET D . n 
D 1 123 ASP 123 198  198  ASP ASP D . n 
D 1 124 THR 124 199  199  THR THR D . n 
D 1 125 VAL 125 200  200  VAL VAL D . n 
D 1 126 ILE 126 201  201  ILE ILE D . n 
D 1 127 SER 127 202  202  SER SER D . n 
D 1 128 LEU 128 203  203  LEU LEU D . n 
D 1 129 LEU 129 204  204  LEU LEU D . n 
D 1 130 THR 130 205  205  THR THR D . n 
D 1 131 GLY 131 206  206  GLY GLY D . n 
D 1 132 LEU 132 207  207  LEU LEU D . n 
D 1 133 SER 133 208  208  SER SER D . n 
D 1 134 ASP 134 209  209  ASP ASP D . n 
D 1 135 SER 135 210  210  SER SER D . n 
D 1 136 GLN 136 211  211  GLN GLN D . n 
D 1 137 VAL 137 212  212  VAL VAL D . n 
D 1 138 ARG 138 213  213  ARG ARG D . n 
D 1 139 ALA 139 214  214  ALA ALA D . n 
D 1 140 PHE 140 215  215  PHE PHE D . n 
D 1 141 ARG 141 216  216  ARG ARG D . n 
D 1 142 HIS 142 217  217  HIS HIS D . n 
D 1 143 THR 143 218  218  THR THR D . n 
D 1 144 SER 144 219  219  SER SER D . n 
D 1 145 THR 145 220  220  THR THR D . n 
D 1 146 LEU 146 221  221  LEU LEU D . n 
D 1 147 ALA 147 222  222  ALA ALA D . n 
D 1 148 ALA 148 223  223  ALA ALA D . n 
D 1 149 MET 149 224  224  MET MET D . n 
D 1 150 LYS 150 225  225  LYS LYS D . n 
D 1 151 LEU 151 226  226  LEU LEU D . n 
D 1 152 MET 152 227  227  MET MET D . n 
D 1 153 THR 153 228  228  THR THR D . n 
D 1 154 ALA 154 229  229  ALA ALA D . n 
D 1 155 LEU 155 230  230  LEU LEU D . n 
D 1 156 VAL 156 231  231  VAL VAL D . n 
D 1 157 ASN 157 232  232  ASN ASN D . n 
D 1 158 VAL 158 233  233  VAL VAL D . n 
D 1 159 ALA 159 234  234  ALA ALA D . n 
D 1 160 LEU 160 235  235  LEU LEU D . n 
D 1 161 ASN 161 236  236  ASN ASN D . n 
D 1 162 LEU 162 237  237  LEU LEU D . n 
D 1 163 SER 163 238  238  SER SER D . n 
D 1 164 ILE 164 239  239  ILE ILE D . n 
D 1 165 ASN 165 240  240  ASN ASN D . n 
D 1 166 MET 166 241  241  MET MET D . n 
D 1 167 ASP 167 242  242  ASP ASP D . n 
D 1 168 ASN 168 243  243  ASN ASN D . n 
D 1 169 THR 169 244  244  THR THR D . n 
D 1 170 GLN 170 245  245  GLN GLN D . n 
D 1 171 ARG 171 246  246  ARG ARG D . n 
D 1 172 GLN 172 247  247  GLN GLN D . n 
D 1 173 TYR 173 248  248  TYR TYR D . n 
D 1 174 GLU 174 249  249  GLU GLU D . n 
D 1 175 ALA 175 250  250  ALA ALA D . n 
D 1 176 GLU 176 251  251  GLU GLU D . n 
D 1 177 ARG 177 252  252  ARG ARG D . n 
D 1 178 ASN 178 253  253  ASN ASN D . n 
D 1 179 LYS 179 254  254  LYS LYS D . n 
D 1 180 MET 180 255  255  MET MET D . n 
D 1 181 ILE 181 256  256  ILE ILE D . n 
D 1 182 GLY 182 257  ?    ?   ?   D . n 
D 1 183 LYS 183 258  ?    ?   ?   D . n 
D 1 184 ARG 184 259  ?    ?   ?   D . n 
D 1 185 ALA 185 260  260  ALA ALA D . n 
D 1 186 ASN 186 261  261  ASN ASN D . n 
D 1 187 GLU 187 262  262  GLU GLU D . n 
D 1 188 ARG 188 263  263  ARG ARG D . n 
D 1 189 LEU 189 264  264  LEU LEU D . n 
D 1 190 GLU 190 265  265  GLU GLU D . n 
D 1 191 LEU 191 266  266  LEU LEU D . n 
D 1 192 LEU 192 267  267  LEU LEU D . n 
D 1 193 LEU 193 268  268  LEU LEU D . n 
D 1 194 GLN 194 269  269  GLN GLN D . n 
D 1 195 LYS 195 270  270  LYS LYS D . n 
D 1 196 ARG 196 271  271  ARG ARG D . n 
D 1 197 LYS 197 272  272  LYS LYS D . n 
D 1 198 GLU 198 273  273  GLU GLU D . n 
D 1 199 LEU 199 274  274  LEU LEU D . n 
D 1 200 GLN 200 275  275  GLN GLN D . n 
D 1 201 GLU 201 276  276  GLU GLU D . n 
D 1 202 ASN 202 277  277  ASN ASN D . n 
D 1 203 GLN 203 278  278  GLN GLN D . n 
D 1 204 ASP 204 279  279  ASP ASP D . n 
D 1 205 GLU 205 280  280  GLU GLU D . n 
D 1 206 ILE 206 281  281  ILE ILE D . n 
D 1 207 GLU 207 282  282  GLU GLU D . n 
D 1 208 ASN 208 283  283  ASN ASN D . n 
D 1 209 MET 209 284  284  MET MET D . n 
D 1 210 MET 210 285  285  MET MET D . n 
D 1 211 ASN 211 286  286  ASN ASN D . n 
D 1 212 ALA 212 287  287  ALA ALA D . n 
D 1 213 ILE 213 288  288  ILE ILE D . n 
D 1 214 PHE 214 289  289  PHE PHE D . n 
D 1 215 LYS 215 290  290  LYS LYS D . n 
D 1 216 GLY 216 291  291  GLY GLY D . n 
D 1 217 VAL 217 292  292  VAL VAL D . n 
D 1 218 PHE 218 293  293  PHE PHE D . n 
D 1 219 VAL 219 294  294  VAL VAL D . n 
D 1 220 HIS 220 295  295  HIS HIS D . n 
D 1 221 ARG 221 296  296  ARG ARG D . n 
D 1 222 TYR 222 297  297  TYR TYR D . n 
D 1 223 ARG 223 298  298  ARG ARG D . n 
D 1 224 ASP 224 299  299  ASP ASP D . n 
D 1 225 ALA 225 300  300  ALA ALA D . n 
D 1 226 ILE 226 301  301  ILE ILE D . n 
D 1 227 ALA 227 302  302  ALA ALA D . n 
D 1 228 GLU 228 303  303  GLU GLU D . n 
D 1 229 ILE 229 304  304  ILE ILE D . n 
D 1 230 ARG 230 305  305  ARG ARG D . n 
D 1 231 ALA 231 306  306  ALA ALA D . n 
D 1 232 ILE 232 307  307  ILE ILE D . n 
D 1 233 CYS 233 308  308  CYS CYS D . n 
D 1 234 ILE 234 309  309  ILE ILE D . n 
D 1 235 GLU 235 310  310  GLU GLU D . n 
D 1 236 GLU 236 311  311  GLU GLU D . n 
D 1 237 ILE 237 312  312  ILE ILE D . n 
D 1 238 GLY 238 313  313  GLY GLY D . n 
D 1 239 ILE 239 314  314  ILE ILE D . n 
D 1 240 TRP 240 315  315  TRP TRP D . n 
D 1 241 MET 241 316  316  MET MET D . n 
D 1 242 LYS 242 317  317  LYS LYS D . n 
D 1 243 MET 243 318  318  MET MET D . n 
D 1 244 TYR 244 319  319  TYR TYR D . n 
D 1 245 SER 245 320  320  SER SER D . n 
D 1 246 ASP 246 321  321  ASP ASP D . n 
D 1 247 ALA 247 322  322  ALA ALA D . n 
D 1 248 PHE 248 323  323  PHE PHE D . n 
D 1 249 LEU 249 324  324  LEU LEU D . n 
D 1 250 ASN 250 325  325  ASN ASN D . n 
D 1 251 ASP 251 326  326  ASP ASP D . n 
D 1 252 SER 252 327  327  SER SER D . n 
D 1 253 TYR 253 328  328  TYR TYR D . n 
D 1 254 LEU 254 329  329  LEU LEU D . n 
D 1 255 LYS 255 330  330  LYS LYS D . n 
D 1 256 TYR 256 331  331  TYR TYR D . n 
D 1 257 VAL 257 332  332  VAL VAL D . n 
D 1 258 GLY 258 333  333  GLY GLY D . n 
D 1 259 TRP 259 334  334  TRP TRP D . n 
D 1 260 THR 260 335  335  THR THR D . n 
D 1 261 MET 261 336  336  MET MET D . n 
D 1 262 HIS 262 337  337  HIS HIS D . n 
D 1 263 ASP 263 338  338  ASP ASP D . n 
D 1 264 LYS 264 339  339  LYS LYS D . n 
D 1 265 GLN 265 340  340  GLN GLN D . n 
D 1 266 GLY 266 341  341  GLY GLY D . n 
D 1 267 GLU 267 342  342  GLU GLU D . n 
D 1 268 VAL 268 343  343  VAL VAL D . n 
D 1 269 ARG 269 344  344  ARG ARG D . n 
D 1 270 LEU 270 345  345  LEU LEU D . n 
D 1 271 LYS 271 346  346  LYS LYS D . n 
D 1 272 CYS 272 347  347  CYS CYS D . n 
D 1 273 LEU 273 348  348  LEU LEU D . n 
D 1 274 THR 274 349  349  THR THR D . n 
D 1 275 ALA 275 350  350  ALA ALA D . n 
D 1 276 LEU 276 351  351  LEU LEU D . n 
D 1 277 GLN 277 352  352  GLN GLN D . n 
D 1 278 GLY 278 353  353  GLY GLY D . n 
D 1 279 LEU 279 354  354  LEU LEU D . n 
D 1 280 TYR 280 355  355  TYR TYR D . n 
D 1 281 TYR 281 356  356  TYR TYR D . n 
D 1 282 ASN 282 357  357  ASN ASN D . n 
D 1 283 LYS 283 358  358  LYS LYS D . n 
D 1 284 GLU 284 359  359  GLU GLU D . n 
D 1 285 LEU 285 360  360  LEU LEU D . n 
D 1 286 ASN 286 361  361  ASN ASN D . n 
D 1 287 SER 287 362  362  SER SER D . n 
D 1 288 LYS 288 363  363  LYS LYS D . n 
D 1 289 LEU 289 364  364  LEU LEU D . n 
D 1 290 GLU 290 365  365  GLU GLU D . n 
D 1 291 LEU 291 366  366  LEU LEU D . n 
D 1 292 PHE 292 367  367  PHE PHE D . n 
D 1 293 THR 293 368  368  THR THR D . n 
D 1 294 SER 294 369  369  SER SER D . n 
D 1 295 ARG 295 370  370  ARG ARG D . n 
D 1 296 PHE 296 371  371  PHE PHE D . n 
D 1 297 LYS 297 372  372  LYS LYS D . n 
D 1 298 ASP 298 373  373  ASP ASP D . n 
D 1 299 ARG 299 374  374  ARG ARG D . n 
D 1 300 ILE 300 375  375  ILE ILE D . n 
D 1 301 VAL 301 376  376  VAL VAL D . n 
D 1 302 SER 302 377  377  SER SER D . n 
D 1 303 MET 303 378  378  MET MET D . n 
D 1 304 THR 304 379  379  THR THR D . n 
D 1 305 LEU 305 380  380  LEU LEU D . n 
D 1 306 ASP 306 381  381  ASP ASP D . n 
D 1 307 LYS 307 382  382  LYS LYS D . n 
D 1 308 GLU 308 383  383  GLU GLU D . n 
D 1 309 TYR 309 384  384  TYR TYR D . n 
D 1 310 ASP 310 385  385  ASP ASP D . n 
D 1 311 VAL 311 386  386  VAL VAL D . n 
D 1 312 ALA 312 387  387  ALA ALA D . n 
D 1 313 VAL 313 388  388  VAL VAL D . n 
D 1 314 GLN 314 389  389  GLN GLN D . n 
D 1 315 ALA 315 390  390  ALA ALA D . n 
D 1 316 ILE 316 391  391  ILE ILE D . n 
D 1 317 LYS 317 392  392  LYS LYS D . n 
D 1 318 LEU 318 393  393  LEU LEU D . n 
D 1 319 LEU 319 394  394  LEU LEU D . n 
D 1 320 THR 320 395  395  THR THR D . n 
D 1 321 LEU 321 396  396  LEU LEU D . n 
D 1 322 VAL 322 397  397  VAL VAL D . n 
D 1 323 LEU 323 398  398  LEU LEU D . n 
D 1 324 GLN 324 399  399  GLN GLN D . n 
D 1 325 SER 325 400  400  SER SER D . n 
D 1 326 SER 326 401  401  SER SER D . n 
D 1 327 GLU 327 402  402  GLU GLU D . n 
D 1 328 GLU 328 403  403  GLU GLU D . n 
D 1 329 VAL 329 404  404  VAL VAL D . n 
D 1 330 LEU 330 405  405  LEU LEU D . n 
D 1 331 THR 331 406  406  THR THR D . n 
D 1 332 ALA 332 407  407  ALA ALA D . n 
D 1 333 GLU 333 408  408  GLU GLU D . n 
D 1 334 ASP 334 409  409  ASP ASP D . n 
D 1 335 CYS 335 410  410  CYS CYS D . n 
D 1 336 GLU 336 411  411  GLU GLU D . n 
D 1 337 ASN 337 412  412  ASN ASN D . n 
D 1 338 VAL 338 413  413  VAL VAL D . n 
D 1 339 TYR 339 414  414  TYR TYR D . n 
D 1 340 HIS 340 415  415  HIS HIS D . n 
D 1 341 LEU 341 416  416  LEU LEU D . n 
D 1 342 VAL 342 417  417  VAL VAL D . n 
D 1 343 TYR 343 418  418  TYR TYR D . n 
D 1 344 SER 344 419  419  SER SER D . n 
D 1 345 ALA 345 420  420  ALA ALA D . n 
D 1 346 HIS 346 421  421  HIS HIS D . n 
D 1 347 ARG 347 422  422  ARG ARG D . n 
D 1 348 PRO 348 423  423  PRO PRO D . n 
D 1 349 VAL 349 424  424  VAL VAL D . n 
D 1 350 ALA 350 425  425  ALA ALA D . n 
D 1 351 VAL 351 426  426  VAL VAL D . n 
D 1 352 ALA 352 427  427  ALA ALA D . n 
D 1 353 ALA 353 428  428  ALA ALA D . n 
D 1 354 GLY 354 429  429  GLY GLY D . n 
D 1 355 GLU 355 430  430  GLU GLU D . n 
D 1 356 PHE 356 431  431  PHE PHE D . n 
D 1 357 LEU 357 432  432  LEU LEU D . n 
D 1 358 TYR 358 433  433  TYR TYR D . n 
D 1 359 LYS 359 434  434  LYS LYS D . n 
D 1 360 LYS 360 435  435  LYS LYS D . n 
D 1 361 LEU 361 436  436  LEU LEU D . n 
D 1 362 PHE 362 437  437  PHE PHE D . n 
D 1 363 SER 363 438  438  SER SER D . n 
D 1 364 ARG 364 439  439  ARG ARG D . n 
D 1 365 ARG 365 440  440  ARG ARG D . n 
D 1 366 ASP 366 441  ?    ?   ?   D . n 
D 1 367 PRO 367 442  ?    ?   ?   D . n 
D 1 368 GLU 368 443  ?    ?   ?   D . n 
D 1 369 GLU 369 444  ?    ?   ?   D . n 
D 1 370 ASP 370 445  ?    ?   ?   D . n 
D 1 371 GLY 371 446  ?    ?   ?   D . n 
D 1 372 LEU 372 447  ?    ?   ?   D . n 
D 1 373 MET 373 448  ?    ?   ?   D . n 
D 1 374 LYS 374 449  ?    ?   ?   D . n 
D 1 375 ARG 375 450  ?    ?   ?   D . n 
D 1 376 ARG 376 451  ?    ?   ?   D . n 
D 1 377 GLY 377 452  ?    ?   ?   D . n 
D 1 378 ARG 378 453  ?    ?   ?   D . n 
D 1 379 GLN 379 454  454  GLN GLN D . n 
D 1 380 GLY 380 455  455  GLY GLY D . n 
D 1 381 PRO 381 456  456  PRO PRO D . n 
D 1 382 ASN 382 457  457  ASN ASN D . n 
D 1 383 ALA 383 458  458  ALA ALA D . n 
D 1 384 ASN 384 459  459  ASN ASN D . n 
D 1 385 LEU 385 460  460  LEU LEU D . n 
D 1 386 VAL 386 461  461  VAL VAL D . n 
D 1 387 LYS 387 462  462  LYS LYS D . n 
D 1 388 THR 388 463  463  THR THR D . n 
D 1 389 LEU 389 464  464  LEU LEU D . n 
D 1 390 VAL 390 465  465  VAL VAL D . n 
D 1 391 PHE 391 466  466  PHE PHE D . n 
D 1 392 PHE 392 467  467  PHE PHE D . n 
D 1 393 PHE 393 468  468  PHE PHE D . n 
D 1 394 LEU 394 469  469  LEU LEU D . n 
D 1 395 GLU 395 470  470  GLU GLU D . n 
D 1 396 SER 396 471  471  SER SER D . n 
D 1 397 GLU 397 472  472  GLU GLU D . n 
D 1 398 LEU 398 473  473  LEU LEU D . n 
D 1 399 HIS 399 474  474  HIS HIS D . n 
D 1 400 GLU 400 475  475  GLU GLU D . n 
D 1 401 HIS 401 476  476  HIS HIS D . n 
D 1 402 ALA 402 477  477  ALA ALA D . n 
D 1 403 ALA 403 478  478  ALA ALA D . n 
D 1 404 TYR 404 479  479  TYR TYR D . n 
D 1 405 LEU 405 480  480  LEU LEU D . n 
D 1 406 VAL 406 481  481  VAL VAL D . n 
D 1 407 ASP 407 482  482  ASP ASP D . n 
D 1 408 SER 408 483  483  SER SER D . n 
D 1 409 MET 409 484  484  MET MET D . n 
D 1 410 TRP 410 485  485  TRP TRP D . n 
D 1 411 ASP 411 486  486  ASP ASP D . n 
D 1 412 CYS 412 487  487  CYS CYS D . n 
D 1 413 ALA 413 488  488  ALA ALA D . n 
D 1 414 THR 414 489  489  THR THR D . n 
D 1 415 GLU 415 490  490  GLU GLU D . n 
D 1 416 LEU 416 491  491  LEU LEU D . n 
D 1 417 LEU 417 492  492  LEU LEU D . n 
D 1 418 LYS 418 493  493  LYS LYS D . n 
D 1 419 ASP 419 494  494  ASP ASP D . n 
D 1 420 TRP 420 495  495  TRP TRP D . n 
D 1 421 GLU 421 496  496  GLU GLU D . n 
D 1 422 CYS 422 497  497  CYS CYS D . n 
D 1 423 MET 423 498  498  MET MET D . n 
D 1 424 ASN 424 499  499  ASN ASN D . n 
D 1 425 SER 425 500  500  SER SER D . n 
D 1 426 LEU 426 501  501  LEU LEU D . n 
D 1 427 LEU 427 502  502  LEU LEU D . n 
D 1 428 LEU 428 503  503  LEU LEU D . n 
D 1 429 GLU 429 504  504  GLU GLU D . n 
D 1 430 GLU 430 505  505  GLU GLU D . n 
D 1 431 PRO 431 506  506  PRO PRO D . n 
D 1 432 LEU 432 507  507  LEU LEU D . n 
D 1 433 SER 433 508  508  SER SER D . n 
D 1 434 GLY 434 509  509  GLY GLY D . n 
D 1 435 GLU 435 510  510  GLU GLU D . n 
D 1 436 GLU 436 511  511  GLU GLU D . n 
D 1 437 ALA 437 512  512  ALA ALA D . n 
D 1 438 LEU 438 513  513  LEU LEU D . n 
D 1 439 THR 439 514  514  THR THR D . n 
D 1 440 ASP 440 515  515  ASP ASP D . n 
D 1 441 ARG 441 516  516  ARG ARG D . n 
D 1 442 GLN 442 517  517  GLN GLN D . n 
D 1 443 GLU 443 518  518  GLU GLU D . n 
D 1 444 SER 444 519  519  SER SER D . n 
D 1 445 ALA 445 520  520  ALA ALA D . n 
D 1 446 LEU 446 521  521  LEU LEU D . n 
D 1 447 ILE 447 522  522  ILE ILE D . n 
D 1 448 GLU 448 523  523  GLU GLU D . n 
D 1 449 ILE 449 524  524  ILE ILE D . n 
D 1 450 MET 450 525  525  MET MET D . n 
D 1 451 LEU 451 526  526  LEU LEU D . n 
D 1 452 CYS 452 527  527  CYS CYS D . n 
D 1 453 THR 453 528  528  THR THR D . n 
D 1 454 ILE 454 529  529  ILE ILE D . n 
D 1 455 ARG 455 530  530  ARG ARG D . n 
D 1 456 GLN 456 531  531  GLN GLN D . n 
D 1 457 ALA 457 532  532  ALA ALA D . n 
D 1 458 ALA 458 533  533  ALA ALA D . n 
D 1 459 GLU 459 534  534  GLU GLU D . n 
D 1 460 CYS 460 535  535  CYS CYS D . n 
D 1 461 HIS 461 536  536  HIS HIS D . n 
D 1 462 PRO 462 537  537  PRO PRO D . n 
D 1 463 PRO 463 538  538  PRO PRO D . n 
D 1 464 VAL 464 539  539  VAL VAL D . n 
D 1 465 GLY 465 540  540  GLY GLY D . n 
D 1 466 ARG 466 541  541  ARG ARG D . n 
D 1 467 GLY 467 542  542  GLY GLY D . n 
D 1 468 THR 468 543  543  THR THR D . n 
D 1 469 GLY 469 544  544  GLY GLY D . n 
D 1 470 LYS 470 545  545  LYS LYS D . n 
D 1 471 ARG 471 546  546  ARG ARG D . n 
D 1 472 VAL 472 547  547  VAL VAL D . n 
D 1 473 LEU 473 548  548  LEU LEU D . n 
D 1 474 THR 474 549  549  THR THR D . n 
D 1 475 ALA 475 550  550  ALA ALA D . n 
D 1 476 LYS 476 551  551  LYS LYS D . n 
D 1 477 GLU 477 552  552  GLU GLU D . n 
D 1 478 LYS 478 553  553  LYS LYS D . n 
D 1 479 LYS 479 554  554  LYS LYS D . n 
D 1 480 THR 480 555  555  THR THR D . n 
D 1 481 GLN 481 556  556  GLN GLN D . n 
D 1 482 LEU 482 557  557  LEU LEU D . n 
D 1 483 ASP 483 558  558  ASP ASP D . n 
D 1 484 ASP 484 559  559  ASP ASP D . n 
D 1 485 ARG 485 560  560  ARG ARG D . n 
D 1 486 THR 486 561  561  THR THR D . n 
D 1 487 ARG 487 562  562  ARG ARG D . n 
D 1 488 ILE 488 563  563  ILE ILE D . n 
D 1 489 THR 489 564  564  THR THR D . n 
D 1 490 GLU 490 565  565  GLU GLU D . n 
D 1 491 LEU 491 566  566  LEU LEU D . n 
D 1 492 PHE 492 567  567  PHE PHE D . n 
D 1 493 ALA 493 568  568  ALA ALA D . n 
D 1 494 VAL 494 569  569  VAL VAL D . n 
D 1 495 ALA 495 570  570  ALA ALA D . n 
D 1 496 LEU 496 571  571  LEU LEU D . n 
D 1 497 PRO 497 572  572  PRO PRO D . n 
D 1 498 GLN 498 573  573  GLN GLN D . n 
D 1 499 LEU 499 574  574  LEU LEU D . n 
D 1 500 LEU 500 575  575  LEU LEU D . n 
D 1 501 ALA 501 576  576  ALA ALA D . n 
D 1 502 LYS 502 577  577  LYS LYS D . n 
D 1 503 TYR 503 578  578  TYR TYR D . n 
D 1 504 SER 504 579  579  SER SER D . n 
D 1 505 VAL 505 580  580  VAL VAL D . n 
D 1 506 ASP 506 581  581  ASP ASP D . n 
D 1 507 ALA 507 582  582  ALA ALA D . n 
D 1 508 GLU 508 583  583  GLU GLU D . n 
D 1 509 LYS 509 584  584  LYS LYS D . n 
D 1 510 VAL 510 585  585  VAL VAL D . n 
D 1 511 THR 511 586  586  THR THR D . n 
D 1 512 ASN 512 587  587  ASN ASN D . n 
D 1 513 LEU 513 588  588  LEU LEU D . n 
D 1 514 LEU 514 589  589  LEU LEU D . n 
D 1 515 GLN 515 590  590  GLN GLN D . n 
D 1 516 LEU 516 591  591  LEU LEU D . n 
D 1 517 PRO 517 592  592  PRO PRO D . n 
D 1 518 GLN 518 593  593  GLN GLN D . n 
D 1 519 TYR 519 594  594  TYR TYR D . n 
D 1 520 PHE 520 595  595  PHE PHE D . n 
D 1 521 ASP 521 596  596  ASP ASP D . n 
D 1 522 LEU 522 597  597  LEU LEU D . n 
D 1 523 GLU 523 598  598  GLU GLU D . n 
D 1 524 ILE 524 599  599  ILE ILE D . n 
D 1 525 TYR 525 600  600  TYR TYR D . n 
D 1 526 THR 526 601  601  THR THR D . n 
D 1 527 THR 527 602  602  THR THR D . n 
D 1 528 GLY 528 603  603  GLY GLY D . n 
D 1 529 ARG 529 604  604  ARG ARG D . n 
D 1 530 LEU 530 605  605  LEU LEU D . n 
D 1 531 GLU 531 606  606  GLU GLU D . n 
D 1 532 LYS 532 607  607  LYS LYS D . n 
D 1 533 HIS 533 608  608  HIS HIS D . n 
D 1 534 LEU 534 609  609  LEU LEU D . n 
D 1 535 ASP 535 610  610  ASP ASP D . n 
D 1 536 ALA 536 611  611  ALA ALA D . n 
D 1 537 LEU 537 612  612  LEU LEU D . n 
D 1 538 LEU 538 613  613  LEU LEU D . n 
D 1 539 ARG 539 614  614  ARG ARG D . n 
D 1 540 GLN 540 615  615  GLN GLN D . n 
D 1 541 ILE 541 616  616  ILE ILE D . n 
D 1 542 ARG 542 617  617  ARG ARG D . n 
D 1 543 ASN 543 618  618  ASN ASN D . n 
D 1 544 ILE 544 619  619  ILE ILE D . n 
D 1 545 VAL 545 620  620  VAL VAL D . n 
D 1 546 GLU 546 621  621  GLU GLU D . n 
D 1 547 LYS 547 622  622  LYS LYS D . n 
D 1 548 HIS 548 623  623  HIS HIS D . n 
D 1 549 THR 549 624  624  THR THR D . n 
D 1 550 ASP 550 625  625  ASP ASP D . n 
D 1 551 THR 551 626  626  THR THR D . n 
D 1 552 ASP 552 627  627  ASP ASP D . n 
D 1 553 VAL 553 628  628  VAL VAL D . n 
D 1 554 LEU 554 629  629  LEU LEU D . n 
D 1 555 GLU 555 630  630  GLU GLU D . n 
D 1 556 ALA 556 631  631  ALA ALA D . n 
D 1 557 CYS 557 632  632  CYS CYS D . n 
D 1 558 SER 558 633  633  SER SER D . n 
D 1 559 LYS 559 634  634  LYS LYS D . n 
D 1 560 THR 560 635  635  THR THR D . n 
D 1 561 TYR 561 636  636  TYR TYR D . n 
D 1 562 HIS 562 637  637  HIS HIS D . n 
D 1 563 ALA 563 638  638  ALA ALA D . n 
D 1 564 LEU 564 639  639  LEU LEU D . n 
D 1 565 CYS 565 640  640  CYS CYS D . n 
D 1 566 ASN 566 641  641  ASN ASN D . n 
D 1 567 GLU 567 642  642  GLU GLU D . n 
D 1 568 GLU 568 643  643  GLU GLU D . n 
D 1 569 PHE 569 644  644  PHE PHE D . n 
D 1 570 THR 570 645  645  THR THR D . n 
D 1 571 ILE 571 646  646  ILE ILE D . n 
D 1 572 PHE 572 647  647  PHE PHE D . n 
D 1 573 ASN 573 648  648  ASN ASN D . n 
D 1 574 ARG 574 649  649  ARG ARG D . n 
D 1 575 VAL 575 650  650  VAL VAL D . n 
D 1 576 ASP 576 651  651  ASP ASP D . n 
D 1 577 ILE 577 652  652  ILE ILE D . n 
D 1 578 SER 578 653  653  SER SER D . n 
D 1 579 ARG 579 654  654  ARG ARG D . n 
D 1 580 SER 580 655  655  SER SER D . n 
D 1 581 GLN 581 656  656  GLN GLN D . n 
D 1 582 LEU 582 657  657  LEU LEU D . n 
D 1 583 ILE 583 658  658  ILE ILE D . n 
D 1 584 ASP 584 659  659  ASP ASP D . n 
D 1 585 GLU 585 660  660  GLU GLU D . n 
D 1 586 LEU 586 661  661  LEU LEU D . n 
D 1 587 ALA 587 662  662  ALA ALA D . n 
D 1 588 ASP 588 663  663  ASP ASP D . n 
D 1 589 LYS 589 664  664  LYS LYS D . n 
D 1 590 PHE 590 665  665  PHE PHE D . n 
D 1 591 ASN 591 666  666  ASN ASN D . n 
D 1 592 ARG 592 667  667  ARG ARG D . n 
D 1 593 LEU 593 668  668  LEU LEU D . n 
D 1 594 LEU 594 669  669  LEU LEU D . n 
D 1 595 GLU 595 670  670  GLU GLU D . n 
D 1 596 ASP 596 671  671  ASP ASP D . n 
D 1 597 PHE 597 672  672  PHE PHE D . n 
D 1 598 LEU 598 673  673  LEU LEU D . n 
D 1 599 GLN 599 674  674  GLN GLN D . n 
D 1 600 GLU 600 675  675  GLU GLU D . n 
D 1 601 GLY 601 676  676  GLY GLY D . n 
D 1 602 GLU 602 677  677  GLU GLU D . n 
D 1 603 GLU 603 678  678  GLU GLU D . n 
D 1 604 PRO 604 679  679  PRO PRO D . n 
D 1 605 ASP 605 680  680  ASP ASP D . n 
D 1 606 GLU 606 681  681  GLU GLU D . n 
D 1 607 ASP 607 682  682  ASP ASP D . n 
D 1 608 ASP 608 683  683  ASP ASP D . n 
D 1 609 ALA 609 684  684  ALA ALA D . n 
D 1 610 TYR 610 685  685  TYR TYR D . n 
D 1 611 GLN 611 686  686  GLN GLN D . n 
D 1 612 VAL 612 687  687  VAL VAL D . n 
D 1 613 LEU 613 688  688  LEU LEU D . n 
D 1 614 SER 614 689  689  SER SER D . n 
D 1 615 THR 615 690  690  THR THR D . n 
D 1 616 LEU 616 691  691  LEU LEU D . n 
D 1 617 LYS 617 692  692  LYS LYS D . n 
D 1 618 ARG 618 693  693  ARG ARG D . n 
D 1 619 ILE 619 694  694  ILE ILE D . n 
D 1 620 THR 620 695  695  THR THR D . n 
D 1 621 ALA 621 696  696  ALA ALA D . n 
D 1 622 PHE 622 697  697  PHE PHE D . n 
D 1 623 HIS 623 698  698  HIS HIS D . n 
D 1 624 ASN 624 699  699  ASN ASN D . n 
D 1 625 ALA 625 700  700  ALA ALA D . n 
D 1 626 HIS 626 701  701  HIS HIS D . n 
D 1 627 ASP 627 702  702  ASP ASP D . n 
D 1 628 LEU 628 703  703  LEU LEU D . n 
D 1 629 SER 629 704  704  SER SER D . n 
D 1 630 LYS 630 705  705  LYS LYS D . n 
D 1 631 TRP 631 706  706  TRP TRP D . n 
D 1 632 ASP 632 707  707  ASP ASP D . n 
D 1 633 LEU 633 708  708  LEU LEU D . n 
D 1 634 PHE 634 709  709  PHE PHE D . n 
D 1 635 ALA 635 710  710  ALA ALA D . n 
D 1 636 CYS 636 711  711  CYS CYS D . n 
D 1 637 ASN 637 712  712  ASN ASN D . n 
D 1 638 TYR 638 713  713  TYR TYR D . n 
D 1 639 LYS 639 714  714  LYS LYS D . n 
D 1 640 LEU 640 715  715  LEU LEU D . n 
D 1 641 LEU 641 716  716  LEU LEU D . n 
D 1 642 LYS 642 717  717  LYS LYS D . n 
D 1 643 THR 643 718  718  THR THR D . n 
D 1 644 GLY 644 719  719  GLY GLY D . n 
D 1 645 ILE 645 720  720  ILE ILE D . n 
D 1 646 GLU 646 721  721  GLU GLU D . n 
D 1 647 ASN 647 722  722  ASN ASN D . n 
D 1 648 GLY 648 723  723  GLY GLY D . n 
D 1 649 ASP 649 724  724  ASP ASP D . n 
D 1 650 MET 650 725  725  MET MET D . n 
D 1 651 PRO 651 726  726  PRO PRO D . n 
D 1 652 GLU 652 727  727  GLU GLU D . n 
D 1 653 GLN 653 728  728  GLN GLN D . n 
D 1 654 ILE 654 729  729  ILE ILE D . n 
D 1 655 VAL 655 730  730  VAL VAL D . n 
D 1 656 ILE 656 731  731  ILE ILE D . n 
D 1 657 HIS 657 732  732  HIS HIS D . n 
D 1 658 ALA 658 733  733  ALA ALA D . n 
D 1 659 LEU 659 734  734  LEU LEU D . n 
D 1 660 GLN 660 735  735  GLN GLN D . n 
D 1 661 CYS 661 736  736  CYS CYS D . n 
D 1 662 ALA 662 737  737  ALA ALA D . n 
D 1 663 HIS 663 738  738  HIS HIS D . n 
D 1 664 TYR 664 739  739  TYR TYR D . n 
D 1 665 VAL 665 740  740  VAL VAL D . n 
D 1 666 ILE 666 741  741  ILE ILE D . n 
D 1 667 LEU 667 742  742  LEU LEU D . n 
D 1 668 TRP 668 743  743  TRP TRP D . n 
D 1 669 GLN 669 744  744  GLN GLN D . n 
D 1 670 LEU 670 745  745  LEU LEU D . n 
D 1 671 ALA 671 746  746  ALA ALA D . n 
D 1 672 LYS 672 747  747  LYS LYS D . n 
D 1 673 ILE 673 748  748  ILE ILE D . n 
D 1 674 THR 674 749  749  THR THR D . n 
D 1 675 GLU 675 750  750  GLU GLU D . n 
D 1 676 SER 676 751  751  SER SER D . n 
D 1 677 THR 677 752  752  THR THR D . n 
D 1 678 SER 678 753  753  SER SER D . n 
D 1 679 THR 679 754  754  THR THR D . n 
D 1 680 LYS 680 755  755  LYS LYS D . n 
D 1 681 GLU 681 756  756  GLU GLU D . n 
D 1 682 ASP 682 757  757  ASP ASP D . n 
D 1 683 LEU 683 758  758  LEU LEU D . n 
D 1 684 LEU 684 759  759  LEU LEU D . n 
D 1 685 ARG 685 760  760  ARG ARG D . n 
D 1 686 LEU 686 761  761  LEU LEU D . n 
D 1 687 LYS 687 762  762  LYS LYS D . n 
D 1 688 LYS 688 763  763  LYS LYS D . n 
D 1 689 GLN 689 764  764  GLN GLN D . n 
D 1 690 MET 690 765  765  MET MET D . n 
D 1 691 ARG 691 766  766  ARG ARG D . n 
D 1 692 VAL 692 767  767  VAL VAL D . n 
D 1 693 PHE 693 768  768  PHE PHE D . n 
D 1 694 CYS 694 769  769  CYS CYS D . n 
D 1 695 GLN 695 770  770  GLN GLN D . n 
D 1 696 ILE 696 771  771  ILE ILE D . n 
D 1 697 CYS 697 772  772  CYS CYS D . n 
D 1 698 GLN 698 773  773  GLN GLN D . n 
D 1 699 HIS 699 774  774  HIS HIS D . n 
D 1 700 TYR 700 775  775  TYR TYR D . n 
D 1 701 LEU 701 776  776  LEU LEU D . n 
D 1 702 THR 702 777  777  THR THR D . n 
D 1 703 ASN 703 778  778  ASN ASN D . n 
D 1 704 VAL 704 779  779  VAL VAL D . n 
D 1 705 ASN 705 780  780  ASN ASN D . n 
D 1 706 THR 706 781  781  THR THR D . n 
D 1 707 THR 707 782  782  THR THR D . n 
D 1 708 VAL 708 783  783  VAL VAL D . n 
D 1 709 LYS 709 784  784  LYS LYS D . n 
D 1 710 GLU 710 785  785  GLU GLU D . n 
D 1 711 GLN 711 786  786  GLN GLN D . n 
D 1 712 ALA 712 787  787  ALA ALA D . n 
D 1 713 PHE 713 788  788  PHE PHE D . n 
D 1 714 THR 714 789  789  THR THR D . n 
D 1 715 ILE 715 790  790  ILE ILE D . n 
D 1 716 LEU 716 791  791  LEU LEU D . n 
D 1 717 CYS 717 792  792  CYS CYS D . n 
D 1 718 ASP 718 793  793  ASP ASP D . n 
D 1 719 ILE 719 794  794  ILE ILE D . n 
D 1 720 LEU 720 795  795  LEU LEU D . n 
D 1 721 MET 721 796  796  MET MET D . n 
D 1 722 ILE 722 797  797  ILE ILE D . n 
D 1 723 PHE 723 798  798  PHE PHE D . n 
D 1 724 SER 724 799  799  SER SER D . n 
D 1 725 HIS 725 800  800  HIS HIS D . n 
D 1 726 GLN 726 801  801  GLN GLN D . n 
D 1 727 ILE 727 802  802  ILE ILE D . n 
D 1 728 MET 728 803  803  MET MET D . n 
D 1 729 SER 729 804  804  SER SER D . n 
D 1 730 GLY 730 805  805  GLY GLY D . n 
D 1 731 GLY 731 806  806  GLY GLY D . n 
D 1 732 ARG 732 807  807  ARG ARG D . n 
D 1 733 ASP 733 808  808  ASP ASP D . n 
D 1 734 MET 734 809  809  MET MET D . n 
D 1 735 LEU 735 810  810  LEU LEU D . n 
D 1 736 GLU 736 811  811  GLU GLU D . n 
D 1 737 PRO 737 812  812  PRO PRO D . n 
D 1 738 LEU 738 813  813  LEU LEU D . n 
D 1 739 VAL 739 814  814  VAL VAL D . n 
D 1 740 TYR 740 815  815  TYR TYR D . n 
D 1 741 THR 741 816  816  THR THR D . n 
D 1 742 PRO 742 817  817  PRO PRO D . n 
D 1 743 ASP 743 818  818  ASP ASP D . n 
D 1 744 SER 744 819  819  SER SER D . n 
D 1 745 SER 745 820  820  SER SER D . n 
D 1 746 LEU 746 821  821  LEU LEU D . n 
D 1 747 GLN 747 822  822  GLN GLN D . n 
D 1 748 SER 748 823  823  SER SER D . n 
D 1 749 GLU 749 824  824  GLU GLU D . n 
D 1 750 LEU 750 825  825  LEU LEU D . n 
D 1 751 LEU 751 826  826  LEU LEU D . n 
D 1 752 SER 752 827  827  SER SER D . n 
D 1 753 PHE 753 828  828  PHE PHE D . n 
D 1 754 ILE 754 829  829  ILE ILE D . n 
D 1 755 LEU 755 830  830  LEU LEU D . n 
D 1 756 ASP 756 831  831  ASP ASP D . n 
D 1 757 HIS 757 832  832  HIS HIS D . n 
D 1 758 VAL 758 833  833  VAL VAL D . n 
D 1 759 PHE 759 834  834  PHE PHE D . n 
D 1 760 ILE 760 835  835  ILE ILE D . n 
D 1 761 GLU 761 836  836  GLU GLU D . n 
D 1 762 GLN 762 837  837  GLN GLN D . n 
D 1 763 ASP 763 838  ?    ?   ?   D . n 
D 1 764 ASP 764 839  ?    ?   ?   D . n 
D 1 765 ASP 765 840  ?    ?   ?   D . n 
D 1 766 SER 766 841  ?    ?   ?   D . n 
D 1 767 ASN 767 842  ?    ?   ?   D . n 
D 1 768 SER 768 843  ?    ?   ?   D . n 
D 1 769 ALA 769 844  ?    ?   ?   D . n 
D 1 770 ASP 770 845  ?    ?   ?   D . n 
D 1 771 GLY 771 846  ?    ?   ?   D . n 
D 1 772 GLN 772 847  ?    ?   ?   D . n 
D 1 773 GLN 773 848  ?    ?   ?   D . n 
D 1 774 GLU 774 849  ?    ?   ?   D . n 
D 1 775 ASP 775 850  ?    ?   ?   D . n 
D 1 776 GLU 776 851  851  GLU GLU D . n 
D 1 777 ALA 777 852  852  ALA ALA D . n 
D 1 778 SER 778 853  853  SER SER D . n 
D 1 779 LYS 779 854  854  LYS LYS D . n 
D 1 780 ILE 780 855  855  ILE ILE D . n 
D 1 781 GLU 781 856  856  GLU GLU D . n 
D 1 782 ALA 782 857  857  ALA ALA D . n 
D 1 783 LEU 783 858  858  LEU LEU D . n 
D 1 784 HIS 784 859  859  HIS HIS D . n 
D 1 785 LYS 785 860  860  LYS LYS D . n 
D 1 786 ARG 786 861  861  ARG ARG D . n 
D 1 787 ARG 787 862  862  ARG ARG D . n 
D 1 788 ASN 788 863  863  ASN ASN D . n 
D 1 789 LEU 789 864  864  LEU LEU D . n 
D 1 790 LEU 790 865  865  LEU LEU D . n 
D 1 791 ALA 791 866  866  ALA ALA D . n 
D 1 792 ALA 792 867  867  ALA ALA D . n 
D 1 793 PHE 793 868  868  PHE PHE D . n 
D 1 794 CYS 794 869  869  CYS CYS D . n 
D 1 795 LYS 795 870  870  LYS LYS D . n 
D 1 796 LEU 796 871  871  LEU LEU D . n 
D 1 797 ILE 797 872  872  ILE ILE D . n 
D 1 798 VAL 798 873  873  VAL VAL D . n 
D 1 799 TYR 799 874  874  TYR TYR D . n 
D 1 800 THR 800 875  875  THR THR D . n 
D 1 801 VAL 801 876  876  VAL VAL D . n 
D 1 802 VAL 802 877  877  VAL VAL D . n 
D 1 803 GLU 803 878  878  GLU GLU D . n 
D 1 804 MET 804 879  879  MET MET D . n 
D 1 805 ASN 805 880  880  ASN ASN D . n 
D 1 806 THR 806 881  881  THR THR D . n 
D 1 807 ALA 807 882  882  ALA ALA D . n 
D 1 808 ALA 808 883  883  ALA ALA D . n 
D 1 809 ASP 809 884  884  ASP ASP D . n 
D 1 810 ILE 810 885  885  ILE ILE D . n 
D 1 811 PHE 811 886  886  PHE PHE D . n 
D 1 812 LYS 812 887  887  LYS LYS D . n 
D 1 813 GLN 813 888  888  GLN GLN D . n 
D 1 814 TYR 814 889  889  TYR TYR D . n 
D 1 815 MET 815 890  890  MET MET D . n 
D 1 816 LYS 816 891  891  LYS LYS D . n 
D 1 817 TYR 817 892  892  TYR TYR D . n 
D 1 818 TYR 818 893  893  TYR TYR D . n 
D 1 819 ASN 819 894  894  ASN ASN D . n 
D 1 820 ASP 820 895  895  ASP ASP D . n 
D 1 821 TYR 821 896  896  TYR TYR D . n 
D 1 822 GLY 822 897  897  GLY GLY D . n 
D 1 823 ASP 823 898  898  ASP ASP D . n 
D 1 824 ILE 824 899  899  ILE ILE D . n 
D 1 825 ILE 825 900  900  ILE ILE D . n 
D 1 826 LYS 826 901  901  LYS LYS D . n 
D 1 827 GLU 827 902  902  GLU GLU D . n 
D 1 828 THR 828 903  903  THR THR D . n 
D 1 829 MET 829 904  904  MET MET D . n 
D 1 830 SER 830 905  905  SER SER D . n 
D 1 831 LYS 831 906  906  LYS LYS D . n 
D 1 832 THR 832 907  907  THR THR D . n 
D 1 833 ARG 833 908  908  ARG ARG D . n 
D 1 834 GLN 834 909  909  GLN GLN D . n 
D 1 835 ILE 835 910  910  ILE ILE D . n 
D 1 836 ASP 836 911  911  ASP ASP D . n 
D 1 837 LYS 837 912  912  LYS LYS D . n 
D 1 838 ILE 838 913  913  ILE ILE D . n 
D 1 839 GLN 839 914  914  GLN GLN D . n 
D 1 840 CYS 840 915  915  CYS CYS D . n 
D 1 841 ALA 841 916  916  ALA ALA D . n 
D 1 842 LYS 842 917  917  LYS LYS D . n 
D 1 843 THR 843 918  918  THR THR D . n 
D 1 844 LEU 844 919  919  LEU LEU D . n 
D 1 845 ILE 845 920  920  ILE ILE D . n 
D 1 846 LEU 846 921  921  LEU LEU D . n 
D 1 847 SER 847 922  922  SER SER D . n 
D 1 848 LEU 848 923  923  LEU LEU D . n 
D 1 849 GLN 849 924  924  GLN GLN D . n 
D 1 850 GLN 850 925  925  GLN GLN D . n 
D 1 851 LEU 851 926  926  LEU LEU D . n 
D 1 852 PHE 852 927  927  PHE PHE D . n 
D 1 853 ASN 853 928  928  ASN ASN D . n 
D 1 854 GLU 854 929  929  GLU GLU D . n 
D 1 855 MET 855 930  930  MET MET D . n 
D 1 856 ILE 856 931  931  ILE ILE D . n 
D 1 857 GLN 857 932  932  GLN GLN D . n 
D 1 858 GLU 858 933  933  GLU GLU D . n 
D 1 859 ASN 859 934  934  ASN ASN D . n 
D 1 860 GLY 860 935  935  GLY GLY D . n 
D 1 861 TYR 861 936  936  TYR TYR D . n 
D 1 862 ASN 862 937  937  ASN ASN D . n 
D 1 863 PHE 863 938  938  PHE PHE D . n 
D 1 864 ASP 864 939  939  ASP ASP D . n 
D 1 865 ARG 865 940  940  ARG ARG D . n 
D 1 866 SER 866 941  941  SER SER D . n 
D 1 867 SER 867 942  942  SER SER D . n 
D 1 868 SER 868 943  943  SER SER D . n 
D 1 869 THR 869 944  944  THR THR D . n 
D 1 870 PHE 870 945  945  PHE PHE D . n 
D 1 871 SER 871 946  946  SER SER D . n 
D 1 872 GLY 872 947  947  GLY GLY D . n 
D 1 873 ILE 873 948  948  ILE ILE D . n 
D 1 874 LYS 874 949  949  LYS LYS D . n 
D 1 875 GLU 875 950  950  GLU GLU D . n 
D 1 876 LEU 876 951  951  LEU LEU D . n 
D 1 877 ALA 877 952  952  ALA ALA D . n 
D 1 878 ARG 878 953  953  ARG ARG D . n 
D 1 879 ARG 879 954  954  ARG ARG D . n 
D 1 880 PHE 880 955  955  PHE PHE D . n 
D 1 881 ALA 881 956  956  ALA ALA D . n 
D 1 882 LEU 882 957  957  LEU LEU D . n 
D 1 883 THR 883 958  958  THR THR D . n 
D 1 884 PHE 884 959  959  PHE PHE D . n 
D 1 885 GLY 885 960  960  GLY GLY D . n 
D 1 886 LEU 886 961  ?    ?   ?   D . n 
D 1 887 ASP 887 962  ?    ?   ?   D . n 
D 1 888 GLN 888 963  ?    ?   ?   D . n 
D 1 889 LEU 889 964  964  LEU LEU D . n 
D 1 890 LYS 890 965  965  LYS LYS D . n 
D 1 891 THR 891 966  966  THR THR D . n 
D 1 892 ARG 892 967  967  ARG ARG D . n 
D 1 893 GLU 893 968  968  GLU GLU D . n 
D 1 894 ALA 894 969  969  ALA ALA D . n 
D 1 895 ILE 895 970  970  ILE ILE D . n 
D 1 896 ALA 896 971  971  ALA ALA D . n 
D 1 897 MET 897 972  972  MET MET D . n 
D 1 898 LEU 898 973  973  LEU LEU D . n 
D 1 899 HIS 899 974  974  HIS HIS D . n 
D 1 900 LYS 900 975  975  LYS LYS D . n 
D 1 901 ASP 901 976  976  ASP ASP D . n 
D 1 902 GLY 902 977  977  GLY GLY D . n 
D 1 903 ILE 903 978  978  ILE ILE D . n 
D 1 904 GLU 904 979  979  GLU GLU D . n 
D 1 905 PHE 905 980  980  PHE PHE D . n 
D 1 906 ALA 906 981  981  ALA ALA D . n 
D 1 907 PHE 907 982  982  PHE PHE D . n 
D 1 908 LYS 908 983  983  LYS LYS D . n 
D 1 909 GLU 909 984  984  GLU GLU D . n 
D 1 910 PRO 910 985  985  PRO PRO D . n 
D 1 911 ASN 911 986  986  ASN ASN D . n 
D 1 912 PRO 912 987  987  PRO PRO D . n 
D 1 913 GLN 913 988  988  GLN GLN D . n 
D 1 914 GLY 914 989  989  GLY GLY D . n 
D 1 915 GLU 915 990  990  GLU GLU D . n 
D 1 916 SER 916 991  991  SER SER D . n 
D 1 917 HIS 917 992  992  HIS ALA D . n 
D 1 918 PRO 918 993  993  PRO PRO D . n 
D 1 919 PRO 919 994  994  PRO PRO D . n 
D 1 920 LEU 920 995  995  LEU LEU D . n 
D 1 921 ASN 921 996  996  ASN ASN D . n 
D 1 922 LEU 922 997  997  LEU LEU D . n 
D 1 923 ALA 923 998  998  ALA ALA D . n 
D 1 924 PHE 924 999  999  PHE PHE D . n 
D 1 925 LEU 925 1000 1000 LEU LEU D . n 
D 1 926 ASP 926 1001 1001 ASP ASP D . n 
D 1 927 ILE 927 1002 1002 ILE ILE D . n 
D 1 928 LEU 928 1003 1003 LEU LEU D . n 
D 1 929 SER 929 1004 1004 SER SER D . n 
D 1 930 GLU 930 1005 1005 GLU GLU D . n 
D 1 931 PHE 931 1006 1006 PHE PHE D . n 
D 1 932 SER 932 1007 1007 SER SER D . n 
D 1 933 SER 933 1008 1008 SER SER D . n 
D 1 934 LYS 934 1009 1009 LYS LYS D . n 
D 1 935 LEU 935 1010 1010 LEU LEU D . n 
D 1 936 LEU 936 1011 1011 LEU LEU D . n 
D 1 937 ARG 937 1012 1012 ARG ARG D . n 
D 1 938 GLN 938 1013 1013 GLN GLN D . n 
D 1 939 ASP 939 1014 1014 ASP ASP D . n 
D 1 940 LYS 940 1015 1015 LYS LYS D . n 
D 1 941 ARG 941 1016 1016 ARG ARG D . n 
D 1 942 THR 942 1017 1017 THR THR D . n 
D 1 943 VAL 943 1018 1018 VAL VAL D . n 
D 1 944 TYR 944 1019 1019 TYR TYR D . n 
D 1 945 VAL 945 1020 1020 VAL VAL D . n 
D 1 946 TYR 946 1021 1021 TYR TYR D . n 
D 1 947 LEU 947 1022 1022 LEU LEU D . n 
D 1 948 GLU 948 1023 1023 GLU GLU D . n 
D 1 949 LYS 949 1024 1024 LYS LYS D . n 
D 1 950 PHE 950 1025 1025 PHE PHE D . n 
D 1 951 MET 951 1026 1026 MET MET D . n 
D 1 952 THR 952 1027 1027 THR THR D . n 
D 1 953 PHE 953 1028 1028 PHE PHE D . n 
D 1 954 GLN 954 1029 1029 GLN GLN D . n 
D 1 955 MET 955 1030 1030 MET MET D . n 
D 1 956 SER 956 1031 1031 SER SER D . n 
D 1 957 LEU 957 1032 1032 LEU LEU D . n 
D 1 958 ARG 958 1033 1033 ARG ARG D . n 
D 1 959 ARG 959 1034 1034 ARG ARG D . n 
D 1 960 GLU 960 1035 1035 GLU GLU D . n 
D 1 961 ASP 961 1036 1036 ASP ASP D . n 
D 1 962 VAL 962 1037 1037 VAL VAL D . n 
D 1 963 TRP 963 1038 1038 TRP TRP D . n 
D 1 964 LEU 964 1039 1039 LEU LEU D . n 
D 1 965 PRO 965 1040 1040 PRO PRO D . n 
D 1 966 LEU 966 1041 1041 LEU LEU D . n 
D 1 967 MET 967 1042 1042 MET MET D . n 
D 1 968 SER 968 1043 1043 SER SER D . n 
D 1 969 TYR 969 1044 1044 TYR TYR D . n 
D 1 970 ARG 970 1045 1045 ARG ARG D . n 
D 1 971 ASN 971 1046 1046 ASN ASN D . n 
D 1 972 SER 972 1047 1047 SER SER D . n 
D 1 973 LEU 973 1048 1048 LEU LEU D . n 
D 1 974 LEU 974 1049 1049 LEU LEU D . n 
D 1 975 ALA 975 1050 1050 ALA ALA D . n 
D 1 976 GLY 976 1051 1051 GLY GLY D . n 
D 1 977 GLY 977 1052 1052 GLY GLY D . n 
D 1 978 ASP 978 1053 1053 ASP ASP D . n 
D 1 979 ASP 979 1054 1054 ASP ASP D . n 
D 1 980 ASP 980 1055 ?    ?   ?   D . n 
D 1 981 THR 981 1056 ?    ?   ?   D . n 
D 1 982 MET 982 1057 ?    ?   ?   D . n 
D 1 983 SER 983 1058 ?    ?   ?   D . n 
D 1 984 VAL 984 1059 ?    ?   ?   D . n 
D 1 985 ILE 985 1060 ?    ?   ?   D . n 
E 2 1   GLY 1   278  ?    ?   ?   E . n 
E 2 2   PRO 2   279  ?    ?   ?   E . n 
E 2 3   GLY 3   280  ?    ?   ?   E . n 
E 2 4   SER 4   281  ?    ?   ?   E . n 
E 2 5   ASP 5   282  ?    ?   ?   E . n 
E 2 6   PRO 6   283  ?    ?   ?   E . n 
E 2 7   VAL 7   284  ?    ?   ?   E . n 
E 2 8   GLU 8   285  ?    ?   ?   E . n 
E 2 9   PRO 9   286  ?    ?   ?   E . n 
E 2 10  MET 10  287  ?    ?   ?   E . n 
E 2 11  PRO 11  288  ?    ?   ?   E . n 
E 2 12  THR 12  289  ?    ?   ?   E . n 
E 2 13  MET 13  290  ?    ?   ?   E . n 
E 2 14  THR 14  291  ?    ?   ?   E . n 
E 2 15  ASP 15  292  ?    ?   ?   E . n 
E 2 16  GLN 16  293  ?    ?   ?   E . n 
E 2 17  THR 17  294  ?    ?   ?   E . n 
E 2 18  THR 18  295  ?    ?   ?   E . n 
E 2 19  LEU 19  296  ?    ?   ?   E . n 
E 2 20  VAL 20  297  ?    ?   ?   E . n 
E 2 21  PRO 21  298  ?    ?   ?   E . n 
E 2 22  ASN 22  299  ?    ?   ?   E . n 
E 2 23  GLU 23  300  ?    ?   ?   E . n 
E 2 24  GLU 24  301  ?    ?   ?   E . n 
E 2 25  GLU 25  302  ?    ?   ?   E . n 
E 2 26  ALA 26  303  ?    ?   ?   E . n 
E 2 27  PHE 27  304  ?    ?   ?   E . n 
E 2 28  ALA 28  305  ?    ?   ?   E . n 
E 2 29  LEU 29  306  ?    ?   ?   E . n 
E 2 30  GLU 30  307  ?    ?   ?   E . n 
E 2 31  PRO 31  308  ?    ?   ?   E . n 
E 2 32  ILE 32  309  ?    ?   ?   E . n 
E 2 33  ASP 33  310  ?    ?   ?   E . n 
E 2 34  ILE 34  311  ?    ?   ?   E . n 
E 2 35  THR 35  312  ?    ?   ?   E . n 
E 2 36  VAL 36  313  ?    ?   ?   E . n 
E 2 37  LYS 37  314  ?    ?   ?   E . n 
E 2 38  GLU 38  315  ?    ?   ?   E . n 
E 2 39  THR 39  316  ?    ?   ?   E . n 
E 2 40  LYS 40  317  ?    ?   ?   E . n 
E 2 41  ALA 41  318  ?    ?   ?   E . n 
E 2 42  LYS 42  319  ?    ?   ?   E . n 
E 2 43  ARG 43  320  ?    ?   ?   E . n 
E 2 44  LYS 44  321  321  LYS LYS E . n 
E 2 45  ARG 45  322  322  ARG ARG E . n 
E 2 46  LYS 46  323  323  LYS LYS E . n 
E 2 47  LEU 47  324  324  LEU LEU E . n 
E 2 48  ILE 48  325  325  ILE ILE E . n 
E 2 49  VAL 49  326  326  VAL VAL E . n 
E 2 50  ASP 50  327  327  ASP ASP E . n 
E 2 51  SER 51  328  328  SER SER E . n 
E 2 52  VAL 52  329  329  VAL VAL E . n 
E 2 53  LYS 53  330  330  LYS LYS E . n 
E 2 54  GLU 54  331  331  GLU GLU E . n 
E 2 55  LEU 55  332  332  LEU LEU E . n 
E 2 56  ASP 56  333  333  ASP ASP E . n 
E 2 57  SER 57  334  334  SER SER E . n 
E 2 58  LYS 58  335  335  LYS LYS E . n 
E 2 59  THR 59  336  336  THR THR E . n 
E 2 60  ILE 60  337  337  ILE ILE E . n 
E 2 61  ARG 61  338  338  ARG ARG E . n 
E 2 62  ALA 62  339  339  ALA ALA E . n 
E 2 63  GLN 63  340  340  GLN GLN E . n 
E 2 64  LEU 64  341  341  LEU LEU E . n 
E 2 65  SER 65  342  342  SER SER E . n 
E 2 66  ASP 66  343  343  ASP ASP E . n 
E 2 67  TYR 67  344  344  TYR TYR E . n 
E 2 68  SER 68  345  345  SER SER E . n 
E 2 69  ASP 69  346  346  ASP ASP E . n 
E 2 70  ILE 70  347  347  ILE ILE E . n 
E 2 71  VAL 71  348  348  VAL VAL E . n 
E 2 72  THR 72  349  349  THR THR E . n 
E 2 73  THR 73  350  350  THR THR E . n 
E 2 74  LEU 74  351  351  LEU LEU E . n 
E 2 75  ASP 75  352  352  ASP ASP E . n 
E 2 76  LEU 76  353  353  LEU LEU E . n 
E 2 77  ALA 77  354  354  ALA ALA E . n 
E 2 78  PRO 78  355  355  PRO PRO E . n 
E 2 79  PRO 79  356  356  PRO PRO E . n 
E 2 80  THR 80  357  357  THR THR E . n 
E 2 81  LYS 81  358  358  LYS LYS E . n 
E 2 82  LYS 82  359  359  LYS LYS E . n 
E 2 83  LEU 83  360  360  LEU LEU E . n 
E 2 84  MET 84  361  361  MET MET E . n 
E 2 85  MET 85  362  362  MET MET E . n 
E 2 86  TRP 86  363  363  TRP TRP E . n 
E 2 87  LYS 87  364  364  LYS LYS E . n 
E 2 88  GLU 88  365  365  GLU GLU E . n 
E 2 89  THR 89  366  366  THR THR E . n 
E 2 90  GLY 90  367  367  GLY GLY E . n 
E 2 91  GLY 91  368  368  GLY GLY E . n 
E 2 92  VAL 92  369  369  VAL VAL E . n 
E 2 93  GLU 93  370  370  GLU GLU E . n 
E 2 94  LYS 94  371  371  LYS LYS E . n 
E 2 95  LEU 95  372  372  LEU LEU E . n 
E 2 96  PHE 96  373  373  PHE PHE E . n 
E 2 97  PHE 97  374  374  PHE PHE E . n 
E 2 98  LEU 98  375  375  LEU LEU E . n 
E 2 99  PRO 99  376  376  PRO PRO E . n 
E 2 100 ALA 100 377  377  ALA ALA E . n 
E 2 101 GLN 101 378  378  GLN GLN E . n 
E 2 102 PRO 102 379  379  PRO PRO E . n 
E 2 103 LEU 103 380  380  LEU LEU E . n 
E 2 104 TRP 104 381  381  TRP TRP E . n 
E 2 105 ASN 105 382  382  ASN ASN E . n 
E 2 106 ASN 106 383  383  ASN ASN E . n 
E 2 107 ARG 107 384  384  ARG ARG E . n 
E 2 108 LEU 108 385  385  LEU LEU E . n 
E 2 109 LEU 109 386  386  LEU LEU E . n 
E 2 110 LYS 110 387  387  LYS LYS E . n 
E 2 111 LEU 111 388  388  LEU LEU E . n 
E 2 112 PHE 112 389  389  PHE PHE E . n 
E 2 113 THR 113 390  390  THR THR E . n 
E 2 114 ARG 114 391  391  ARG ARG E . n 
E 2 115 CYS 115 392  392  CYS CYS E . n 
E 2 116 LEU 116 393  393  LEU LEU E . n 
E 2 117 THR 117 394  394  THR THR E . n 
E 2 118 PRO 118 395  ?    ?   ?   E . n 
E 2 119 LEU 119 396  ?    ?   ?   E . n 
E 2 120 VAL 120 397  ?    ?   ?   E . n 
E 2 121 PRO 121 398  ?    ?   ?   E . n 
E 2 122 GLU 122 399  ?    ?   ?   E . n 
E 2 123 ASP 123 400  ?    ?   ?   E . n 
E 2 124 LEU 124 401  ?    ?   ?   E . n 
E 2 125 ARG 125 402  ?    ?   ?   E . n 
E 2 126 LYS 126 403  ?    ?   ?   E . n 
E 2 127 ARG 127 404  ?    ?   ?   E . n 
E 2 128 ARG 128 405  ?    ?   ?   E . n 
E 2 129 LYS 129 406  ?    ?   ?   E . n 
E 2 130 GLY 130 407  ?    ?   ?   E . n 
E 2 131 GLY 131 408  ?    ?   ?   E . n 
E 2 132 GLU 132 409  ?    ?   ?   E . n 
E 2 133 ALA 133 410  ?    ?   ?   E . n 
E 2 134 ASP 134 411  ?    ?   ?   E . n 
E 2 135 ASN 135 412  ?    ?   ?   E . n 
E 2 136 LEU 136 413  ?    ?   ?   E . n 
E 2 137 ASP 137 414  ?    ?   ?   E . n 
E 2 138 GLU 138 415  ?    ?   ?   E . n 
E 2 139 PHE 139 416  ?    ?   ?   E . n 
E 2 140 LEU 140 417  ?    ?   ?   E . n 
E 2 141 LYS 141 418  ?    ?   ?   E . n 
E 2 142 GLU 142 419  ?    ?   ?   E . n 
E 2 143 PHE 143 420  ?    ?   ?   E . n 
F 3 1   GLY 1   217  ?    ?   ?   F . n 
F 3 2   PRO 2   218  ?    ?   ?   F . n 
F 3 3   GLY 3   219  ?    ?   ?   F . n 
F 3 4   SER 4   220  ?    ?   ?   F . n 
F 3 5   PRO 5   221  ?    ?   ?   F . n 
F 3 6   VAL 6   222  ?    ?   ?   F . n 
F 3 7   LYS 7   223  ?    ?   ?   F . n 
F 3 8   ASP 8   224  224  ASP ASP F . n 
F 3 9   GLU 9   225  225  GLU GLU F . n 
F 3 10  TYR 10  226  226  TYR TYR F . n 
F 3 11  GLU 11  227  227  GLU GLU F . n 
F 3 12  PHE 12  228  228  PHE PHE F . n 
F 3 13  ASP 13  229  229  ASP ASP F . n 
F 3 14  GLU 14  230  230  GLU GLU F . n 
F 3 15  ASP 15  231  231  ASP ASP F . n 
F 3 16  ASP 16  232  232  ASP ASP F . n 
F 3 17  GLU 17  233  233  GLU GLU F . n 
F 3 18  GLN 18  234  234  GLN GLN F . n 
F 3 19  ASP 19  235  235  ASP ASP F . n 
F 3 20  ARG 20  236  236  ARG ARG F . n 
F 3 21  VAL 21  237  237  VAL VAL F . n 
F 3 22  PRO 22  238  238  PRO PRO F . n 
F 3 23  PRO 23  239  239  PRO PRO F . n 
F 3 24  VAL 24  240  240  VAL VAL F . n 
F 3 25  ASP 25  241  241  ASP ASP F . n 
F 3 26  ASP 26  242  242  ASP ASP F . n 
F 3 27  LYS 27  243  243  LYS LYS F . n 
F 3 28  HIS 28  244  244  HIS HIS F . n 
F 3 29  LEU 29  245  245  LEU LEU F . n 
F 3 30  LEU 30  246  246  LEU LEU F . n 
F 3 31  LYS 31  247  247  LYS LYS F . n 
F 3 32  LYS 32  248  ?    ?   ?   F . n 
F 3 33  ASP 33  249  ?    ?   ?   F . n 
F 3 34  TYR 34  250  ?    ?   ?   F . n 
F 3 35  ARG 35  251  ?    ?   ?   F . n 
F 3 36  LYS 36  252  ?    ?   ?   F . n 
F 3 37  GLU 37  253  ?    ?   ?   F . n 
F 3 38  ALA 38  254  ?    ?   ?   F . n 
F 3 39  LYS 39  255  ?    ?   ?   F . n 
F 3 40  ALA 40  256  ?    ?   ?   F . n 
F 3 41  ASN 41  257  ?    ?   ?   F . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 4 HOH 1 1101 6  HOH HOH A . 
G 4 HOH 2 1102 4  HOH HOH A . 
G 4 HOH 3 1103 5  HOH HOH A . 
G 4 HOH 4 1104 15 HOH HOH A . 
G 4 HOH 5 1105 11 HOH HOH A . 
G 4 HOH 6 1106 8  HOH HOH A . 
H 4 HOH 1 301  9  HOH HOH C . 
I 4 HOH 1 1101 10 HOH HOH D . 
I 4 HOH 2 1102 1  HOH HOH D . 
I 4 HOH 3 1103 7  HOH HOH D . 
I 4 HOH 4 1104 12 HOH HOH D . 
I 4 HOH 5 1105 2  HOH HOH D . 
I 4 HOH 6 1106 14 HOH HOH D . 
J 4 HOH 1 501  3  HOH HOH E . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A VAL 1037 ? CG1 ? A VAL 962 CG1 
2 1 Y 1 A VAL 1037 ? CG2 ? A VAL 962 CG2 
3 1 Y 1 D HIS 992  ? CG  ? D HIS 917 CG  
4 1 Y 1 D HIS 992  ? ND1 ? D HIS 917 ND1 
5 1 Y 1 D HIS 992  ? CD2 ? D HIS 917 CD2 
6 1 Y 1 D HIS 992  ? CE1 ? D HIS 917 CE1 
7 1 Y 1 D HIS 992  ? NE2 ? D HIS 917 NE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.20.1_4487: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .                    2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? DIALS  ? ? ? .                    3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .                    4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9J0A 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     280.535 
_cell.length_a_esd                 ? 
_cell.length_b                     48.773 
_cell.length_b_esd                 ? 
_cell.length_c                     290.906 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9J0A 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'I 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9J0A 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.69 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          66.63 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.8 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.02 M citric acid, 0.08 M BIS-TRIS propane (pH 8.8), and 16% w/v polyethylene glycol 3,350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-01-08 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    'LN2-cooled DCM with Si(111) crystals' 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97915 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL18U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97915 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL18U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9J0A 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.30 
_reflns.d_resolution_low                               50 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     60932 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.99 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.45 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.214 
_reflns.pdbx_Rpim_I_all                                0.084 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.196 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.30 
_reflns_shell.d_res_low                                     3.36 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.9 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2973 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               6.76 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.523 
_reflns_shell.pdbx_Rpim_I_all                               0.580 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.606 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.406 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9J0A 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.30 
_refine.ls_d_res_low                             31.88 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     60740 
_refine.ls_number_reflns_R_free                  3185 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.84 
_refine.ls_percent_reflns_R_free                 5.24 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2351 
_refine.ls_R_factor_R_free                       0.2792 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2326 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      6QNX 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 29.11 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.46 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        16792 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.number_atoms_solvent             14 
_refine_hist.number_atoms_total               16806 
_refine_hist.d_res_high                       3.30 
_refine_hist.d_res_low                        31.88 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.003 ? 17085 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.627 ? 23031 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 4.159 ? 2226  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.037 ? 2613  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.007 ? 2922  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.30 3.35  . . 132 2463 100.00 . . . . 0.3243 . . . . . . . . . . . 0.3817 
'X-RAY DIFFRACTION' 3.35 3.40  . . 137 2457 100.00 . . . . 0.3287 . . . . . . . . . . . 0.3511 
'X-RAY DIFFRACTION' 3.40 3.46  . . 127 2521 99.00  . . . . 0.3466 . . . . . . . . . . . 0.4183 
'X-RAY DIFFRACTION' 3.46 3.52  . . 161 2448 100.00 . . . . 0.3230 . . . . . . . . . . . 0.3570 
'X-RAY DIFFRACTION' 3.52 3.58  . . 162 2424 100.00 . . . . 0.3027 . . . . . . . . . . . 0.2918 
'X-RAY DIFFRACTION' 3.58 3.65  . . 158 2439 100.00 . . . . 0.2957 . . . . . . . . . . . 0.3387 
'X-RAY DIFFRACTION' 3.65 3.72  . . 162 2462 100.00 . . . . 0.2806 . . . . . . . . . . . 0.3374 
'X-RAY DIFFRACTION' 3.72 3.80  . . 127 2468 100.00 . . . . 0.2690 . . . . . . . . . . . 0.2908 
'X-RAY DIFFRACTION' 3.80 3.89  . . 109 2495 100.00 . . . . 0.2566 . . . . . . . . . . . 0.3084 
'X-RAY DIFFRACTION' 3.89 3.99  . . 132 2516 100.00 . . . . 0.2486 . . . . . . . . . . . 0.3126 
'X-RAY DIFFRACTION' 3.99 4.10  . . 148 2466 100.00 . . . . 0.2395 . . . . . . . . . . . 0.3138 
'X-RAY DIFFRACTION' 4.10 4.22  . . 127 2506 100.00 . . . . 0.2175 . . . . . . . . . . . 0.2601 
'X-RAY DIFFRACTION' 4.22 4.35  . . 129 2475 100.00 . . . . 0.2159 . . . . . . . . . . . 0.2748 
'X-RAY DIFFRACTION' 4.35 4.51  . . 97  2552 100.00 . . . . 0.2120 . . . . . . . . . . . 0.2615 
'X-RAY DIFFRACTION' 4.51 4.69  . . 129 2489 100.00 . . . . 0.2040 . . . . . . . . . . . 0.2618 
'X-RAY DIFFRACTION' 4.69 4.90  . . 142 2548 100.00 . . . . 0.2075 . . . . . . . . . . . 0.2358 
'X-RAY DIFFRACTION' 4.90 5.16  . . 157 2434 100.00 . . . . 0.2226 . . . . . . . . . . . 0.2750 
'X-RAY DIFFRACTION' 5.16 5.48  . . 141 2573 100.00 . . . . 0.2255 . . . . . . . . . . . 0.2805 
'X-RAY DIFFRACTION' 5.48 5.90  . . 96  2526 100.00 . . . . 0.2434 . . . . . . . . . . . 0.2903 
'X-RAY DIFFRACTION' 5.90 6.49  . . 158 2507 100.00 . . . . 0.2512 . . . . . . . . . . . 0.2833 
'X-RAY DIFFRACTION' 6.49 7.42  . . 147 2561 100.00 . . . . 0.2309 . . . . . . . . . . . 0.3164 
'X-RAY DIFFRACTION' 7.42 9.31  . . 161 2584 100.00 . . . . 0.1746 . . . . . . . . . . . 0.2073 
'X-RAY DIFFRACTION' 9.31 31.88 . . 146 2641 98.00  . . . . 0.1787 . . . . . . . . . . . 0.2193 
# 
_struct.entry_id                     9J0A 
_struct.title                        'Complex structure of ANKRD11/STAG2/RAD21' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9J0A 
_struct_keywords.text            'Complex, PROTEIN BINDING' 
_struct_keywords.pdbx_keywords   'PROTEIN BINDING' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
I N N 4 ? 
J N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP STAG2_MOUSE O35638 ? 1 
;ENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDY
PLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSI
NMDNTQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGIWMKMY
SDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQ
SSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPEEDGLMKRRGRQGPNANLVKTLVFFFLESELHEHAAY
LVDSMWDCATELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKTQLDD
RTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHAL
CNEEFTIFNRVDISRSQLIDELADKFNRLLEDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTG
IENGDMPEQIVIHALQCAHYVILWQLAKITESTSTKEDLLRLKKQMRVFCQICQHYLTNVNTTVKEQAFTILCDILMIFS
HQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEM
NTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTF
GLDQLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWL
PLMSYRNSLLAGGDDDTMSVI
;
80  
2 UNP RAD21_MOUSE Q61550 ? 2 
;DPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLM
MWKETGGVEKLFFLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEF
;
282 
3 UNP ANR11_MOUSE E9Q4F7 ? 3 PVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKEAKAN 342 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9J0A A 5 ? 985 ? O35638 80  ? 1060 ? 80  1060 
2 2 9J0A B 5 ? 143 ? Q61550 282 ? 420  ? 282 420  
3 3 9J0A C 5 ? 41  ? E9Q4F7 342 ? 378  ? 221 257  
4 1 9J0A D 5 ? 985 ? O35638 80  ? 1060 ? 80  1060 
5 2 9J0A E 5 ? 143 ? Q61550 282 ? 420  ? 282 420  
6 3 9J0A F 5 ? 41  ? E9Q4F7 342 ? 378  ? 221 257  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9J0A GLY A 1 ? UNP O35638 ? ? 'expression tag' 76  1  
1 9J0A PRO A 2 ? UNP O35638 ? ? 'expression tag' 77  2  
1 9J0A GLY A 3 ? UNP O35638 ? ? 'expression tag' 78  3  
1 9J0A SER A 4 ? UNP O35638 ? ? 'expression tag' 79  4  
2 9J0A GLY B 1 ? UNP Q61550 ? ? 'expression tag' 278 5  
2 9J0A PRO B 2 ? UNP Q61550 ? ? 'expression tag' 279 6  
2 9J0A GLY B 3 ? UNP Q61550 ? ? 'expression tag' 280 7  
2 9J0A SER B 4 ? UNP Q61550 ? ? 'expression tag' 281 8  
3 9J0A GLY C 1 ? UNP E9Q4F7 ? ? 'expression tag' 217 9  
3 9J0A PRO C 2 ? UNP E9Q4F7 ? ? 'expression tag' 218 10 
3 9J0A GLY C 3 ? UNP E9Q4F7 ? ? 'expression tag' 219 11 
3 9J0A SER C 4 ? UNP E9Q4F7 ? ? 'expression tag' 220 12 
4 9J0A GLY D 1 ? UNP O35638 ? ? 'expression tag' 76  13 
4 9J0A PRO D 2 ? UNP O35638 ? ? 'expression tag' 77  14 
4 9J0A GLY D 3 ? UNP O35638 ? ? 'expression tag' 78  15 
4 9J0A SER D 4 ? UNP O35638 ? ? 'expression tag' 79  16 
5 9J0A GLY E 1 ? UNP Q61550 ? ? 'expression tag' 278 17 
5 9J0A PRO E 2 ? UNP Q61550 ? ? 'expression tag' 279 18 
5 9J0A GLY E 3 ? UNP Q61550 ? ? 'expression tag' 280 19 
5 9J0A SER E 4 ? UNP Q61550 ? ? 'expression tag' 281 20 
6 9J0A GLY F 1 ? UNP E9Q4F7 ? ? 'expression tag' 217 21 
6 9J0A PRO F 2 ? UNP E9Q4F7 ? ? 'expression tag' 218 22 
6 9J0A GLY F 3 ? UNP E9Q4F7 ? ? 'expression tag' 219 23 
6 9J0A SER F 4 ? UNP E9Q4F7 ? ? 'expression tag' 220 24 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA trimeric 3 
2 author_and_software_defined_assembly PISA trimeric 3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 9030  ? 
1 MORE         -34   ? 
1 'SSA (A^2)'  45150 ? 
2 'ABSA (A^2)' 9190  ? 
2 MORE         -32   ? 
2 'SSA (A^2)'  46600 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,C,G,H 
2 1 D,E,F,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'isothermal titration calorimetry' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1   AA1 MET A 8   ? GLY A 16  ? MET A 83   GLY A 91   1 ? 9  
HELX_P HELX_P2   AA2 ALA A 19  ? ASP A 34  ? ALA A 94   ASP A 109  1 ? 16 
HELX_P HELX_P3   AA3 ASP A 34  ? SER A 50  ? ASP A 109  SER A 125  1 ? 17 
HELX_P HELX_P4   AA4 THR A 57  ? HIS A 63  ? THR A 132  HIS A 138  1 ? 7  
HELX_P HELX_P5   AA5 GLN A 65  ? GLU A 76  ? GLN A 140  GLU A 151  1 ? 12 
HELX_P HELX_P6   AA6 GLY A 90  ? GLN A 112 ? GLY A 165  GLN A 187  1 ? 23 
HELX_P HELX_P7   AA7 SER A 114 ? GLU A 119 ? SER A 189  GLU A 194  5 ? 6  
HELX_P HELX_P8   AA8 TYR A 120 ? ASP A 134 ? TYR A 195  ASP A 209  1 ? 15 
HELX_P HELX_P9   AA9 VAL A 137 ? LYS A 179 ? VAL A 212  LYS A 254  1 ? 43 
HELX_P HELX_P10  AB1 GLU A 187 ? VAL A 217 ? GLU A 262  VAL A 292  1 ? 31 
HELX_P HELX_P11  AB2 VAL A 217 ? TYR A 222 ? VAL A 292  TYR A 297  1 ? 6  
HELX_P HELX_P12  AB3 ILE A 226 ? TYR A 244 ? ILE A 301  TYR A 319  1 ? 19 
HELX_P HELX_P13  AB4 TYR A 244 ? LEU A 249 ? TYR A 319  LEU A 324  1 ? 6  
HELX_P HELX_P14  AB5 ASN A 250 ? MET A 261 ? ASN A 325  MET A 336  1 ? 12 
HELX_P HELX_P15  AB6 GLN A 265 ? ASN A 282 ? GLN A 340  ASN A 357  1 ? 18 
HELX_P HELX_P16  AB7 LYS A 288 ? THR A 304 ? LYS A 363  THR A 379  1 ? 17 
HELX_P HELX_P17  AB8 GLU A 308 ? SER A 326 ? GLU A 383  SER A 401  1 ? 19 
HELX_P HELX_P18  AB9 GLU A 327 ? LEU A 330 ? GLU A 402  LEU A 405  5 ? 4  
HELX_P HELX_P19  AC1 THR A 331 ? LEU A 341 ? THR A 406  LEU A 416  1 ? 11 
HELX_P HELX_P20  AC2 VAL A 342 ? SER A 344 ? VAL A 417  SER A 419  5 ? 3  
HELX_P HELX_P21  AC3 HIS A 346 ? LEU A 361 ? HIS A 421  LEU A 436  1 ? 16 
HELX_P HELX_P22  AC4 ASN A 382 ? SER A 396 ? ASN A 457  SER A 471  1 ? 15 
HELX_P HELX_P23  AC5 ALA A 402 ? TRP A 410 ? ALA A 477  TRP A 485  1 ? 9  
HELX_P HELX_P24  AC6 ALA A 413 ? LYS A 418 ? ALA A 488  LYS A 493  1 ? 6  
HELX_P HELX_P25  AC7 ASP A 419 ? LEU A 428 ? ASP A 494  LEU A 503  1 ? 10 
HELX_P HELX_P26  AC8 THR A 439 ? GLU A 459 ? THR A 514  GLU A 534  1 ? 21 
HELX_P HELX_P27  AC9 THR A 474 ? TYR A 503 ? THR A 549  TYR A 578  1 ? 30 
HELX_P HELX_P28  AD1 ASP A 506 ? GLN A 515 ? ASP A 581  GLN A 590  1 ? 10 
HELX_P HELX_P29  AD2 LEU A 516 ? PHE A 520 ? LEU A 591  PHE A 595  5 ? 5  
HELX_P HELX_P30  AD3 ASP A 521 ? GLY A 528 ? ASP A 596  GLY A 603  1 ? 8  
HELX_P HELX_P31  AD4 LEU A 530 ? HIS A 548 ? LEU A 605  HIS A 623  1 ? 19 
HELX_P HELX_P32  AD5 ASP A 550 ? CYS A 565 ? ASP A 625  CYS A 640  1 ? 16 
HELX_P HELX_P33  AD6 ILE A 571 ? LEU A 598 ? ILE A 646  LEU A 673  1 ? 28 
HELX_P HELX_P34  AD7 ASP A 605 ? HIS A 626 ? ASP A 680  HIS A 701  1 ? 22 
HELX_P HELX_P35  AD8 LEU A 628 ? ASP A 632 ? LEU A 703  ASP A 707  5 ? 5  
HELX_P HELX_P36  AD9 LEU A 633 ? GLY A 648 ? LEU A 708  GLY A 723  1 ? 16 
HELX_P HELX_P37  AE1 PRO A 651 ? ILE A 673 ? PRO A 726  ILE A 748  1 ? 23 
HELX_P HELX_P38  AE2 LYS A 680 ? THR A 702 ? LYS A 755  THR A 777  1 ? 23 
HELX_P HELX_P39  AE3 ASN A 705 ? PHE A 723 ? ASN A 780  PHE A 798  1 ? 19 
HELX_P HELX_P40  AE4 SER A 724 ? SER A 729 ? SER A 799  SER A 804  5 ? 6  
HELX_P HELX_P41  AE5 ARG A 732 ? GLU A 736 ? ARG A 807  GLU A 811  5 ? 5  
HELX_P HELX_P42  AE6 ASP A 743 ? VAL A 758 ? ASP A 818  VAL A 833  1 ? 16 
HELX_P HELX_P43  AE7 GLU A 776 ? TYR A 799 ? GLU A 851  TYR A 874  1 ? 24 
HELX_P HELX_P44  AE8 GLU A 803 ? ASN A 805 ? GLU A 878  ASN A 880  5 ? 3  
HELX_P HELX_P45  AE9 THR A 806 ? GLN A 813 ? THR A 881  GLN A 888  1 ? 8  
HELX_P HELX_P46  AF1 TYR A 817 ? ASP A 836 ? TYR A 892  ASP A 911  1 ? 20 
HELX_P HELX_P47  AF2 ASP A 836 ? ASN A 859 ? ASP A 911  ASN A 934  1 ? 24 
HELX_P HELX_P48  AF3 SER A 867 ? THR A 883 ? SER A 942  THR A 958  1 ? 17 
HELX_P HELX_P49  AF4 LYS A 890 ? PHE A 907 ? LYS A 965  PHE A 982  1 ? 18 
HELX_P HELX_P50  AF5 ALA A 923 ? GLU A 930 ? ALA A 998  GLU A 1005 1 ? 8  
HELX_P HELX_P51  AF6 LEU A 936 ? THR A 952 ? LEU A 1011 THR A 1027 1 ? 17 
HELX_P HELX_P52  AF7 PHE A 953 ? ARG A 958 ? PHE A 1028 ARG A 1033 1 ? 6  
HELX_P HELX_P53  AF8 TRP A 963 ? LEU A 973 ? TRP A 1038 LEU A 1048 1 ? 11 
HELX_P HELX_P54  AF9 ASP B 56  ? ASP B 66  ? ASP B 333  ASP B 343  1 ? 11 
HELX_P HELX_P55  AG1 TYR B 67  ? VAL B 71  ? TYR B 344  VAL B 348  5 ? 5  
HELX_P HELX_P56  AG2 THR B 80  ? GLY B 90  ? THR B 357  GLY B 367  1 ? 11 
HELX_P HELX_P57  AG3 GLY B 91  ? PHE B 96  ? GLY B 368  PHE B 373  1 ? 6  
HELX_P HELX_P58  AG4 ASN B 105 ? LEU B 116 ? ASN B 382  LEU B 393  1 ? 12 
HELX_P HELX_P59  AG5 MET D 8   ? GLY D 16  ? MET D 83   GLY D 91   1 ? 9  
HELX_P HELX_P60  AG6 ALA D 19  ? ASP D 34  ? ALA D 94   ASP D 109  1 ? 16 
HELX_P HELX_P61  AG7 ASP D 34  ? SER D 50  ? ASP D 109  SER D 125  1 ? 17 
HELX_P HELX_P62  AG8 THR D 57  ? HIS D 63  ? THR D 132  HIS D 138  1 ? 7  
HELX_P HELX_P63  AG9 GLN D 65  ? GLU D 76  ? GLN D 140  GLU D 151  1 ? 12 
HELX_P HELX_P64  AH1 GLY D 90  ? GLN D 112 ? GLY D 165  GLN D 187  1 ? 23 
HELX_P HELX_P65  AH2 SER D 114 ? ASP D 118 ? SER D 189  ASP D 193  5 ? 5  
HELX_P HELX_P66  AH3 TYR D 120 ? SER D 135 ? TYR D 195  SER D 210  1 ? 16 
HELX_P HELX_P67  AH4 VAL D 137 ? LYS D 179 ? VAL D 212  LYS D 254  1 ? 43 
HELX_P HELX_P68  AH5 ASN D 186 ? VAL D 217 ? ASN D 261  VAL D 292  1 ? 32 
HELX_P HELX_P69  AH6 VAL D 217 ? TYR D 222 ? VAL D 292  TYR D 297  1 ? 6  
HELX_P HELX_P70  AH7 ILE D 226 ? TYR D 244 ? ILE D 301  TYR D 319  1 ? 19 
HELX_P HELX_P71  AH8 TYR D 244 ? LEU D 249 ? TYR D 319  LEU D 324  1 ? 6  
HELX_P HELX_P72  AH9 ASN D 250 ? MET D 261 ? ASN D 325  MET D 336  1 ? 12 
HELX_P HELX_P73  AI1 GLN D 265 ? TYR D 281 ? GLN D 340  TYR D 356  1 ? 17 
HELX_P HELX_P74  AI2 ASN D 286 ? THR D 304 ? ASN D 361  THR D 379  1 ? 19 
HELX_P HELX_P75  AI3 GLU D 308 ? GLU D 327 ? GLU D 383  GLU D 402  1 ? 20 
HELX_P HELX_P76  AI4 LEU D 330 ? LEU D 341 ? LEU D 405  LEU D 416  1 ? 12 
HELX_P HELX_P77  AI5 VAL D 342 ? SER D 344 ? VAL D 417  SER D 419  5 ? 3  
HELX_P HELX_P78  AI6 HIS D 346 ? LEU D 361 ? HIS D 421  LEU D 436  1 ? 16 
HELX_P HELX_P79  AI7 ASN D 382 ? SER D 396 ? ASN D 457  SER D 471  1 ? 15 
HELX_P HELX_P80  AI8 ALA D 402 ? ASP D 411 ? ALA D 477  ASP D 486  1 ? 10 
HELX_P HELX_P81  AI9 ALA D 413 ? LYS D 418 ? ALA D 488  LYS D 493  1 ? 6  
HELX_P HELX_P82  AJ1 ASP D 419 ? LEU D 428 ? ASP D 494  LEU D 503  1 ? 10 
HELX_P HELX_P83  AJ2 THR D 439 ? GLU D 459 ? THR D 514  GLU D 534  1 ? 21 
HELX_P HELX_P84  AJ3 THR D 474 ? TYR D 503 ? THR D 549  TYR D 578  1 ? 30 
HELX_P HELX_P85  AJ4 ASP D 506 ? GLN D 515 ? ASP D 581  GLN D 590  1 ? 10 
HELX_P HELX_P86  AJ5 LEU D 516 ? ASP D 521 ? LEU D 591  ASP D 596  5 ? 6  
HELX_P HELX_P87  AJ6 LEU D 522 ? GLY D 528 ? LEU D 597  GLY D 603  1 ? 7  
HELX_P HELX_P88  AJ7 LEU D 530 ? HIS D 548 ? LEU D 605  HIS D 623  1 ? 19 
HELX_P HELX_P89  AJ8 ASP D 550 ? CYS D 565 ? ASP D 625  CYS D 640  1 ? 16 
HELX_P HELX_P90  AJ9 ILE D 571 ? LEU D 598 ? ILE D 646  LEU D 673  1 ? 28 
HELX_P HELX_P91  AK1 ASP D 605 ? HIS D 626 ? ASP D 680  HIS D 701  1 ? 22 
HELX_P HELX_P92  AK2 LEU D 628 ? ASP D 632 ? LEU D 703  ASP D 707  5 ? 5  
HELX_P HELX_P93  AK3 LEU D 633 ? GLY D 648 ? LEU D 708  GLY D 723  1 ? 16 
HELX_P HELX_P94  AK4 PRO D 651 ? THR D 674 ? PRO D 726  THR D 749  1 ? 24 
HELX_P HELX_P95  AK5 GLU D 681 ? THR D 702 ? GLU D 756  THR D 777  1 ? 22 
HELX_P HELX_P96  AK6 ASN D 705 ? PHE D 723 ? ASN D 780  PHE D 798  1 ? 19 
HELX_P HELX_P97  AK7 SER D 724 ? SER D 729 ? SER D 799  SER D 804  5 ? 6  
HELX_P HELX_P98  AK8 ARG D 732 ? GLU D 736 ? ARG D 807  GLU D 811  5 ? 5  
HELX_P HELX_P99  AK9 ASP D 743 ? VAL D 758 ? ASP D 818  VAL D 833  1 ? 16 
HELX_P HELX_P100 AL1 ALA D 777 ? TYR D 799 ? ALA D 852  TYR D 874  1 ? 23 
HELX_P HELX_P101 AL2 GLU D 803 ? ASN D 805 ? GLU D 878  ASN D 880  5 ? 3  
HELX_P HELX_P102 AL3 THR D 806 ? GLN D 813 ? THR D 881  GLN D 888  1 ? 8  
HELX_P HELX_P103 AL4 TYR D 817 ? ASP D 836 ? TYR D 892  ASP D 911  1 ? 20 
HELX_P HELX_P104 AL5 ASP D 836 ? ASN D 859 ? ASP D 911  ASN D 934  1 ? 24 
HELX_P HELX_P105 AL6 SER D 867 ? GLY D 885 ? SER D 942  GLY D 960  1 ? 19 
HELX_P HELX_P106 AL7 THR D 891 ? PHE D 907 ? THR D 966  PHE D 982  1 ? 17 
HELX_P HELX_P107 AL8 ALA D 923 ? SER D 929 ? ALA D 998  SER D 1004 1 ? 7  
HELX_P HELX_P108 AL9 GLU D 930 ? SER D 932 ? GLU D 1005 SER D 1007 5 ? 3  
HELX_P HELX_P109 AM1 LEU D 936 ? PHE D 950 ? LEU D 1011 PHE D 1025 1 ? 15 
HELX_P HELX_P110 AM2 THR D 952 ? ARG D 958 ? THR D 1027 ARG D 1033 1 ? 7  
HELX_P HELX_P111 AM3 TRP D 963 ? LEU D 973 ? TRP D 1038 LEU D 1048 1 ? 11 
HELX_P HELX_P112 AM4 ASP E 56  ? ASP E 66  ? ASP E 333  ASP E 343  1 ? 11 
HELX_P HELX_P113 AM5 TYR E 67  ? VAL E 71  ? TYR E 344  VAL E 348  5 ? 5  
HELX_P HELX_P114 AM6 THR E 80  ? GLY E 90  ? THR E 357  GLY E 367  1 ? 11 
HELX_P HELX_P115 AM7 GLY E 91  ? PHE E 96  ? GLY E 368  PHE E 373  1 ? 6  
HELX_P HELX_P116 AM8 ASN E 105 ? LEU E 116 ? ASN E 382  LEU E 393  1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           D 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            694 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           D 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            697 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            D 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             769 
_struct_conn.ptnr2_auth_asym_id            D 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             772 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.036 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      D 
_pdbx_modification_feature.label_seq_id                       694 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     D 
_pdbx_modification_feature.modified_residue_label_seq_id      697 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       D 
_pdbx_modification_feature.auth_seq_id                        769 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      D 
_pdbx_modification_feature.modified_residue_auth_seq_id       772 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
_pdbx_entry_details.entry_id                   9J0A 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG1 A THR 228 ? ? OE1 A GLU 311 ? ? 2.12 
2 1 O   A PHE 938 ? ? NH2 A ARG 940 ? ? 2.13 
3 1 O   D PHE 215 ? ? OG  D SER 219 ? ? 2.15 
4 1 ND2 D ASN 141 ? ? OD1 F ASP 242 ? ? 2.17 
5 1 OD2 D ASP 111 ? ? OH  D TYR 195 ? ? 2.18 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    NH1 
_pdbx_validate_symm_contact.auth_asym_id_1    D 
_pdbx_validate_symm_contact.auth_comp_id_1    ARG 
_pdbx_validate_symm_contact.auth_seq_id_1     246 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    OE2 
_pdbx_validate_symm_contact.auth_asym_id_2    F 
_pdbx_validate_symm_contact.auth_comp_id_2    GLU 
_pdbx_validate_symm_contact.auth_seq_id_2     227 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   4_445 
_pdbx_validate_symm_contact.dist              2.17 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 189  ? ? -151.73 -70.65  
2  1 TYR A 195  ? ? -130.57 -59.36  
3  1 VAL A 292  ? ? -121.23 -54.36  
4  1 LEU A 360  ? ? 60.81   -75.27  
5  1 SER A 362  ? ? -65.80  62.85   
6  1 LYS A 363  ? ? 63.08   -3.90   
7  1 GLU A 402  ? ? 70.97   -65.15  
8  1 THR A 406  ? ? 54.43   159.02  
9  1 LEU A 436  ? ? -139.07 -40.23  
10 1 ALA A 488  ? ? -96.70  41.35   
11 1 LEU A 503  ? ? -81.17  -82.51  
12 1 GLU A 505  ? ? -128.05 -50.81  
13 1 PRO A 506  ? ? -58.86  98.22   
14 1 SER A 508  ? ? 58.15   -114.97 
15 1 LYS A 545  ? ? -119.56 67.50   
16 1 GLU A 677  ? ? -155.88 81.11   
17 1 LEU A 813  ? ? -91.32  58.54   
18 1 LYS A 965  ? ? 56.21   -6.29   
19 1 ASN A 996  ? ? -96.87  35.22   
20 1 THR A 1027 ? ? 59.63   -116.66 
21 1 PHE A 1028 ? ? -137.64 -36.88  
22 1 ARG A 1034 ? ? -155.72 70.64   
23 1 ASP A 1036 ? ? -132.06 -111.40 
24 1 MET D 90   ? ? -145.06 18.66   
25 1 SER D 189  ? ? -154.85 -69.85  
26 1 TYR D 195  ? ? -143.12 -64.02  
27 1 VAL D 292  ? ? -121.49 -54.47  
28 1 ASN D 361  ? ? -36.39  121.52  
29 1 GLU D 402  ? ? 74.27   -22.70  
30 1 THR D 406  ? ? 57.37   159.29  
31 1 LEU D 436  ? ? -120.91 -60.53  
32 1 ALA D 488  ? ? -91.17  35.26   
33 1 LEU D 503  ? ? -121.66 -76.49  
34 1 THR D 543  ? ? -94.28  -121.38 
35 1 ARG D 1034 ? ? -131.26 -85.27  
36 1 ASP D 1036 ? ? 68.01   -36.39  
37 1 ASP F 229  ? ? -164.95 91.95   
38 1 GLU F 233  ? ? 66.02   -52.07  
39 1 VAL F 240  ? ? 74.91   -49.97  
40 1 LYS F 243  ? ? -66.61  90.42   
41 1 LEU F 246  ? ? 56.66   -123.37 
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   HIS 
_pdbx_validate_peptide_omega.auth_asym_id_1   D 
_pdbx_validate_peptide_omega.auth_seq_id_1    992 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_2   D 
_pdbx_validate_peptide_omega.auth_seq_id_2    993 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -140.55 
# 
_pdbx_validate_planes.id              1 
_pdbx_validate_planes.PDB_model_num   1 
_pdbx_validate_planes.auth_comp_id    ARG 
_pdbx_validate_planes.auth_asym_id    D 
_pdbx_validate_planes.auth_seq_id     440 
_pdbx_validate_planes.PDB_ins_code    ? 
_pdbx_validate_planes.label_alt_id    ? 
_pdbx_validate_planes.rmsd            0.082 
_pdbx_validate_planes.type            'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY 76   ? A GLY 1   
2   1 Y 1 A PRO 77   ? A PRO 2   
3   1 Y 1 A GLY 78   ? A GLY 3   
4   1 Y 1 A SER 79   ? A SER 4   
5   1 Y 1 A GLU 80   ? A GLU 5   
6   1 Y 1 A ASN 81   ? A ASN 6   
7   1 Y 1 A MET 82   ? A MET 7   
8   1 Y 1 A MET 255  ? A MET 180 
9   1 Y 1 A ILE 256  ? A ILE 181 
10  1 Y 1 A GLY 257  ? A GLY 182 
11  1 Y 1 A LYS 258  ? A LYS 183 
12  1 Y 1 A ARG 259  ? A ARG 184 
13  1 Y 1 A ALA 260  ? A ALA 185 
14  1 Y 1 A ASP 441  ? A ASP 366 
15  1 Y 1 A PRO 442  ? A PRO 367 
16  1 Y 1 A GLU 443  ? A GLU 368 
17  1 Y 1 A GLU 444  ? A GLU 369 
18  1 Y 1 A ASP 445  ? A ASP 370 
19  1 Y 1 A GLY 446  ? A GLY 371 
20  1 Y 1 A LEU 447  ? A LEU 372 
21  1 Y 1 A MET 448  ? A MET 373 
22  1 Y 1 A LYS 449  ? A LYS 374 
23  1 Y 1 A ARG 450  ? A ARG 375 
24  1 Y 1 A ARG 451  ? A ARG 376 
25  1 Y 1 A GLY 452  ? A GLY 377 
26  1 Y 1 A ARG 453  ? A ARG 378 
27  1 Y 1 A GLN 454  ? A GLN 379 
28  1 Y 1 A GLY 455  ? A GLY 380 
29  1 Y 1 A ASP 839  ? A ASP 764 
30  1 Y 1 A ASP 840  ? A ASP 765 
31  1 Y 1 A SER 841  ? A SER 766 
32  1 Y 1 A ASN 842  ? A ASN 767 
33  1 Y 1 A SER 843  ? A SER 768 
34  1 Y 1 A ALA 844  ? A ALA 769 
35  1 Y 1 A ASP 845  ? A ASP 770 
36  1 Y 1 A GLY 846  ? A GLY 771 
37  1 Y 1 A GLN 847  ? A GLN 772 
38  1 Y 1 A GLN 848  ? A GLN 773 
39  1 Y 1 A GLU 849  ? A GLU 774 
40  1 Y 1 A PHE 959  ? A PHE 884 
41  1 Y 1 A GLY 960  ? A GLY 885 
42  1 Y 1 A LEU 961  ? A LEU 886 
43  1 Y 1 A GLY 989  ? A GLY 914 
44  1 Y 1 A GLU 990  ? A GLU 915 
45  1 Y 1 A SER 991  ? A SER 916 
46  1 Y 1 A HIS 992  ? A HIS 917 
47  1 Y 1 A PRO 993  ? A PRO 918 
48  1 Y 1 A LEU 1049 ? A LEU 974 
49  1 Y 1 A ALA 1050 ? A ALA 975 
50  1 Y 1 A GLY 1051 ? A GLY 976 
51  1 Y 1 A GLY 1052 ? A GLY 977 
52  1 Y 1 A ASP 1053 ? A ASP 978 
53  1 Y 1 A ASP 1054 ? A ASP 979 
54  1 Y 1 A ASP 1055 ? A ASP 980 
55  1 Y 1 A THR 1056 ? A THR 981 
56  1 Y 1 A MET 1057 ? A MET 982 
57  1 Y 1 A SER 1058 ? A SER 983 
58  1 Y 1 A VAL 1059 ? A VAL 984 
59  1 Y 1 A ILE 1060 ? A ILE 985 
60  1 Y 1 B GLY 278  ? B GLY 1   
61  1 Y 1 B PRO 279  ? B PRO 2   
62  1 Y 1 B GLY 280  ? B GLY 3   
63  1 Y 1 B SER 281  ? B SER 4   
64  1 Y 1 B ASP 282  ? B ASP 5   
65  1 Y 1 B PRO 283  ? B PRO 6   
66  1 Y 1 B VAL 284  ? B VAL 7   
67  1 Y 1 B GLU 285  ? B GLU 8   
68  1 Y 1 B PRO 286  ? B PRO 9   
69  1 Y 1 B MET 287  ? B MET 10  
70  1 Y 1 B PRO 288  ? B PRO 11  
71  1 Y 1 B THR 289  ? B THR 12  
72  1 Y 1 B MET 290  ? B MET 13  
73  1 Y 1 B THR 291  ? B THR 14  
74  1 Y 1 B ASP 292  ? B ASP 15  
75  1 Y 1 B GLN 293  ? B GLN 16  
76  1 Y 1 B THR 294  ? B THR 17  
77  1 Y 1 B THR 295  ? B THR 18  
78  1 Y 1 B LEU 296  ? B LEU 19  
79  1 Y 1 B VAL 297  ? B VAL 20  
80  1 Y 1 B PRO 298  ? B PRO 21  
81  1 Y 1 B ASN 299  ? B ASN 22  
82  1 Y 1 B GLU 300  ? B GLU 23  
83  1 Y 1 B GLU 301  ? B GLU 24  
84  1 Y 1 B GLU 302  ? B GLU 25  
85  1 Y 1 B ALA 303  ? B ALA 26  
86  1 Y 1 B PHE 304  ? B PHE 27  
87  1 Y 1 B ALA 305  ? B ALA 28  
88  1 Y 1 B LEU 306  ? B LEU 29  
89  1 Y 1 B GLU 307  ? B GLU 30  
90  1 Y 1 B PRO 308  ? B PRO 31  
91  1 Y 1 B ILE 309  ? B ILE 32  
92  1 Y 1 B ASP 310  ? B ASP 33  
93  1 Y 1 B ILE 311  ? B ILE 34  
94  1 Y 1 B THR 312  ? B THR 35  
95  1 Y 1 B VAL 313  ? B VAL 36  
96  1 Y 1 B LYS 314  ? B LYS 37  
97  1 Y 1 B GLU 315  ? B GLU 38  
98  1 Y 1 B THR 316  ? B THR 39  
99  1 Y 1 B LYS 317  ? B LYS 40  
100 1 Y 1 B ALA 318  ? B ALA 41  
101 1 Y 1 B LYS 319  ? B LYS 42  
102 1 Y 1 B ARG 320  ? B ARG 43  
103 1 Y 1 B PRO 395  ? B PRO 118 
104 1 Y 1 B LEU 396  ? B LEU 119 
105 1 Y 1 B VAL 397  ? B VAL 120 
106 1 Y 1 B PRO 398  ? B PRO 121 
107 1 Y 1 B GLU 399  ? B GLU 122 
108 1 Y 1 B ASP 400  ? B ASP 123 
109 1 Y 1 B LEU 401  ? B LEU 124 
110 1 Y 1 B ARG 402  ? B ARG 125 
111 1 Y 1 B LYS 403  ? B LYS 126 
112 1 Y 1 B ARG 404  ? B ARG 127 
113 1 Y 1 B ARG 405  ? B ARG 128 
114 1 Y 1 B LYS 406  ? B LYS 129 
115 1 Y 1 B GLY 407  ? B GLY 130 
116 1 Y 1 B GLY 408  ? B GLY 131 
117 1 Y 1 B GLU 409  ? B GLU 132 
118 1 Y 1 B ALA 410  ? B ALA 133 
119 1 Y 1 B ASP 411  ? B ASP 134 
120 1 Y 1 B ASN 412  ? B ASN 135 
121 1 Y 1 B LEU 413  ? B LEU 136 
122 1 Y 1 B ASP 414  ? B ASP 137 
123 1 Y 1 B GLU 415  ? B GLU 138 
124 1 Y 1 B PHE 416  ? B PHE 139 
125 1 Y 1 B LEU 417  ? B LEU 140 
126 1 Y 1 B LYS 418  ? B LYS 141 
127 1 Y 1 B GLU 419  ? B GLU 142 
128 1 Y 1 B PHE 420  ? B PHE 143 
129 1 Y 1 C GLY 217  ? C GLY 1   
130 1 Y 1 C PRO 218  ? C PRO 2   
131 1 Y 1 C GLY 219  ? C GLY 3   
132 1 Y 1 C SER 220  ? C SER 4   
133 1 Y 1 C PRO 221  ? C PRO 5   
134 1 Y 1 C VAL 222  ? C VAL 6   
135 1 Y 1 C LYS 223  ? C LYS 7   
136 1 Y 1 C LYS 248  ? C LYS 32  
137 1 Y 1 C ASP 249  ? C ASP 33  
138 1 Y 1 C TYR 250  ? C TYR 34  
139 1 Y 1 C ARG 251  ? C ARG 35  
140 1 Y 1 C LYS 252  ? C LYS 36  
141 1 Y 1 C GLU 253  ? C GLU 37  
142 1 Y 1 C ALA 254  ? C ALA 38  
143 1 Y 1 C LYS 255  ? C LYS 39  
144 1 Y 1 C ALA 256  ? C ALA 40  
145 1 Y 1 C ASN 257  ? C ASN 41  
146 1 Y 1 D GLY 76   ? D GLY 1   
147 1 Y 1 D PRO 77   ? D PRO 2   
148 1 Y 1 D GLY 78   ? D GLY 3   
149 1 Y 1 D SER 79   ? D SER 4   
150 1 Y 1 D GLU 80   ? D GLU 5   
151 1 Y 1 D ASN 81   ? D ASN 6   
152 1 Y 1 D GLY 257  ? D GLY 182 
153 1 Y 1 D LYS 258  ? D LYS 183 
154 1 Y 1 D ARG 259  ? D ARG 184 
155 1 Y 1 D ASP 441  ? D ASP 366 
156 1 Y 1 D PRO 442  ? D PRO 367 
157 1 Y 1 D GLU 443  ? D GLU 368 
158 1 Y 1 D GLU 444  ? D GLU 369 
159 1 Y 1 D ASP 445  ? D ASP 370 
160 1 Y 1 D GLY 446  ? D GLY 371 
161 1 Y 1 D LEU 447  ? D LEU 372 
162 1 Y 1 D MET 448  ? D MET 373 
163 1 Y 1 D LYS 449  ? D LYS 374 
164 1 Y 1 D ARG 450  ? D ARG 375 
165 1 Y 1 D ARG 451  ? D ARG 376 
166 1 Y 1 D GLY 452  ? D GLY 377 
167 1 Y 1 D ARG 453  ? D ARG 378 
168 1 Y 1 D ASP 838  ? D ASP 763 
169 1 Y 1 D ASP 839  ? D ASP 764 
170 1 Y 1 D ASP 840  ? D ASP 765 
171 1 Y 1 D SER 841  ? D SER 766 
172 1 Y 1 D ASN 842  ? D ASN 767 
173 1 Y 1 D SER 843  ? D SER 768 
174 1 Y 1 D ALA 844  ? D ALA 769 
175 1 Y 1 D ASP 845  ? D ASP 770 
176 1 Y 1 D GLY 846  ? D GLY 771 
177 1 Y 1 D GLN 847  ? D GLN 772 
178 1 Y 1 D GLN 848  ? D GLN 773 
179 1 Y 1 D GLU 849  ? D GLU 774 
180 1 Y 1 D ASP 850  ? D ASP 775 
181 1 Y 1 D LEU 961  ? D LEU 886 
182 1 Y 1 D ASP 962  ? D ASP 887 
183 1 Y 1 D GLN 963  ? D GLN 888 
184 1 Y 1 D ASP 1055 ? D ASP 980 
185 1 Y 1 D THR 1056 ? D THR 981 
186 1 Y 1 D MET 1057 ? D MET 982 
187 1 Y 1 D SER 1058 ? D SER 983 
188 1 Y 1 D VAL 1059 ? D VAL 984 
189 1 Y 1 D ILE 1060 ? D ILE 985 
190 1 Y 1 E GLY 278  ? E GLY 1   
191 1 Y 1 E PRO 279  ? E PRO 2   
192 1 Y 1 E GLY 280  ? E GLY 3   
193 1 Y 1 E SER 281  ? E SER 4   
194 1 Y 1 E ASP 282  ? E ASP 5   
195 1 Y 1 E PRO 283  ? E PRO 6   
196 1 Y 1 E VAL 284  ? E VAL 7   
197 1 Y 1 E GLU 285  ? E GLU 8   
198 1 Y 1 E PRO 286  ? E PRO 9   
199 1 Y 1 E MET 287  ? E MET 10  
200 1 Y 1 E PRO 288  ? E PRO 11  
201 1 Y 1 E THR 289  ? E THR 12  
202 1 Y 1 E MET 290  ? E MET 13  
203 1 Y 1 E THR 291  ? E THR 14  
204 1 Y 1 E ASP 292  ? E ASP 15  
205 1 Y 1 E GLN 293  ? E GLN 16  
206 1 Y 1 E THR 294  ? E THR 17  
207 1 Y 1 E THR 295  ? E THR 18  
208 1 Y 1 E LEU 296  ? E LEU 19  
209 1 Y 1 E VAL 297  ? E VAL 20  
210 1 Y 1 E PRO 298  ? E PRO 21  
211 1 Y 1 E ASN 299  ? E ASN 22  
212 1 Y 1 E GLU 300  ? E GLU 23  
213 1 Y 1 E GLU 301  ? E GLU 24  
214 1 Y 1 E GLU 302  ? E GLU 25  
215 1 Y 1 E ALA 303  ? E ALA 26  
216 1 Y 1 E PHE 304  ? E PHE 27  
217 1 Y 1 E ALA 305  ? E ALA 28  
218 1 Y 1 E LEU 306  ? E LEU 29  
219 1 Y 1 E GLU 307  ? E GLU 30  
220 1 Y 1 E PRO 308  ? E PRO 31  
221 1 Y 1 E ILE 309  ? E ILE 32  
222 1 Y 1 E ASP 310  ? E ASP 33  
223 1 Y 1 E ILE 311  ? E ILE 34  
224 1 Y 1 E THR 312  ? E THR 35  
225 1 Y 1 E VAL 313  ? E VAL 36  
226 1 Y 1 E LYS 314  ? E LYS 37  
227 1 Y 1 E GLU 315  ? E GLU 38  
228 1 Y 1 E THR 316  ? E THR 39  
229 1 Y 1 E LYS 317  ? E LYS 40  
230 1 Y 1 E ALA 318  ? E ALA 41  
231 1 Y 1 E LYS 319  ? E LYS 42  
232 1 Y 1 E ARG 320  ? E ARG 43  
233 1 Y 1 E PRO 395  ? E PRO 118 
234 1 Y 1 E LEU 396  ? E LEU 119 
235 1 Y 1 E VAL 397  ? E VAL 120 
236 1 Y 1 E PRO 398  ? E PRO 121 
237 1 Y 1 E GLU 399  ? E GLU 122 
238 1 Y 1 E ASP 400  ? E ASP 123 
239 1 Y 1 E LEU 401  ? E LEU 124 
240 1 Y 1 E ARG 402  ? E ARG 125 
241 1 Y 1 E LYS 403  ? E LYS 126 
242 1 Y 1 E ARG 404  ? E ARG 127 
243 1 Y 1 E ARG 405  ? E ARG 128 
244 1 Y 1 E LYS 406  ? E LYS 129 
245 1 Y 1 E GLY 407  ? E GLY 130 
246 1 Y 1 E GLY 408  ? E GLY 131 
247 1 Y 1 E GLU 409  ? E GLU 132 
248 1 Y 1 E ALA 410  ? E ALA 133 
249 1 Y 1 E ASP 411  ? E ASP 134 
250 1 Y 1 E ASN 412  ? E ASN 135 
251 1 Y 1 E LEU 413  ? E LEU 136 
252 1 Y 1 E ASP 414  ? E ASP 137 
253 1 Y 1 E GLU 415  ? E GLU 138 
254 1 Y 1 E PHE 416  ? E PHE 139 
255 1 Y 1 E LEU 417  ? E LEU 140 
256 1 Y 1 E LYS 418  ? E LYS 141 
257 1 Y 1 E GLU 419  ? E GLU 142 
258 1 Y 1 E PHE 420  ? E PHE 143 
259 1 Y 1 F GLY 217  ? F GLY 1   
260 1 Y 1 F PRO 218  ? F PRO 2   
261 1 Y 1 F GLY 219  ? F GLY 3   
262 1 Y 1 F SER 220  ? F SER 4   
263 1 Y 1 F PRO 221  ? F PRO 5   
264 1 Y 1 F VAL 222  ? F VAL 6   
265 1 Y 1 F LYS 223  ? F LYS 7   
266 1 Y 1 F LYS 248  ? F LYS 32  
267 1 Y 1 F ASP 249  ? F ASP 33  
268 1 Y 1 F TYR 250  ? F TYR 34  
269 1 Y 1 F ARG 251  ? F ARG 35  
270 1 Y 1 F LYS 252  ? F LYS 36  
271 1 Y 1 F GLU 253  ? F GLU 37  
272 1 Y 1 F ALA 254  ? F ALA 38  
273 1 Y 1 F LYS 255  ? F LYS 39  
274 1 Y 1 F ALA 256  ? F ALA 40  
275 1 Y 1 F ASN 257  ? F ASN 41  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6QNX 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9J0A 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.003565 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.020503 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.003438 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . MET A 1 8   ? 84.737  7.199   43.689  1.00 74.94  ? 83   MET A N   1 
ATOM   2     C CA  . MET A 1 8   ? 84.205  6.069   44.442  1.00 101.99 ? 83   MET A CA  1 
ATOM   3     C C   . MET A 1 8   ? 83.355  6.543   45.619  1.00 105.03 ? 83   MET A C   1 
ATOM   4     O O   . MET A 1 8   ? 82.413  5.864   46.031  1.00 103.00 ? 83   MET A O   1 
ATOM   5     C CB  . MET A 1 8   ? 85.346  5.176   44.941  1.00 89.26  ? 83   MET A CB  1 
ATOM   6     C CG  . MET A 1 8   ? 84.894  3.890   45.619  1.00 108.47 ? 83   MET A CG  1 
ATOM   7     S SD  . MET A 1 8   ? 84.020  2.782   44.497  1.00 146.75 ? 83   MET A SD  1 
ATOM   8     C CE  . MET A 1 8   ? 82.686  2.207   45.546  1.00 85.47  ? 83   MET A CE  1 
ATOM   9     N N   . LEU A 1 9   ? 83.692  7.725   46.142  1.00 95.19  ? 84   LEU A N   1 
ATOM   10    C CA  . LEU A 1 9   ? 83.053  8.220   47.358  1.00 91.92  ? 84   LEU A CA  1 
ATOM   11    C C   . LEU A 1 9   ? 81.550  8.392   47.164  1.00 93.63  ? 84   LEU A C   1 
ATOM   12    O O   . LEU A 1 9   ? 80.753  8.033   48.044  1.00 95.54  ? 84   LEU A O   1 
ATOM   13    C CB  . LEU A 1 9   ? 83.697  9.542   47.773  1.00 79.17  ? 84   LEU A CB  1 
ATOM   14    C CG  . LEU A 1 9   ? 83.580  9.952   49.237  1.00 68.72  ? 84   LEU A CG  1 
ATOM   15    C CD1 . LEU A 1 9   ? 84.368  8.978   50.084  1.00 74.20  ? 84   LEU A CD1 1 
ATOM   16    C CD2 . LEU A 1 9   ? 84.087  11.367  49.443  1.00 76.84  ? 84   LEU A CD2 1 
ATOM   17    N N   . PHE A 1 10  ? 81.147  8.941   46.014  1.00 85.30  ? 85   PHE A N   1 
ATOM   18    C CA  . PHE A 1 10  ? 79.726  9.102   45.725  1.00 81.06  ? 85   PHE A CA  1 
ATOM   19    C C   . PHE A 1 10  ? 79.000  7.766   45.746  1.00 87.93  ? 85   PHE A C   1 
ATOM   20    O O   . PHE A 1 10  ? 77.885  7.670   46.266  1.00 99.54  ? 85   PHE A O   1 
ATOM   21    C CB  . PHE A 1 10  ? 79.528  9.778   44.370  1.00 88.47  ? 85   PHE A CB  1 
ATOM   22    C CG  . PHE A 1 10  ? 78.096  9.791   43.910  1.00 82.92  ? 85   PHE A CG  1 
ATOM   23    C CD1 . PHE A 1 10  ? 77.124  10.460  44.637  1.00 88.88  ? 85   PHE A CD1 1 
ATOM   24    C CD2 . PHE A 1 10  ? 77.718  9.116   42.761  1.00 91.41  ? 85   PHE A CD2 1 
ATOM   25    C CE1 . PHE A 1 10  ? 75.805  10.464  44.219  1.00 82.86  ? 85   PHE A CE1 1 
ATOM   26    C CE2 . PHE A 1 10  ? 76.401  9.116   42.339  1.00 95.59  ? 85   PHE A CE2 1 
ATOM   27    C CZ  . PHE A 1 10  ? 75.443  9.791   43.070  1.00 85.85  ? 85   PHE A CZ  1 
ATOM   28    N N   . GLU A 1 11  ? 79.611  6.724   45.179  1.00 92.27  ? 86   GLU A N   1 
ATOM   29    C CA  . GLU A 1 11  ? 78.963  5.416   45.154  1.00 101.23 ? 86   GLU A CA  1 
ATOM   30    C C   . GLU A 1 11  ? 78.809  4.856   46.564  1.00 104.54 ? 86   GLU A C   1 
ATOM   31    O O   . GLU A 1 11  ? 77.751  4.309   46.917  1.00 112.36 ? 86   GLU A O   1 
ATOM   32    C CB  . GLU A 1 11  ? 79.769  4.458   44.277  1.00 96.50  ? 86   GLU A CB  1 
ATOM   33    C CG  . GLU A 1 11  ? 79.834  4.860   42.812  1.00 97.55  ? 86   GLU A CG  1 
ATOM   34    C CD  . GLU A 1 11  ? 78.476  4.866   42.137  1.00 111.50 ? 86   GLU A CD  1 
ATOM   35    O OE1 . GLU A 1 11  ? 77.827  3.800   42.095  1.00 109.85 ? 86   GLU A OE1 1 
ATOM   36    O OE2 . GLU A 1 11  ? 78.058  5.936   41.647  1.00 117.73 ? 86   GLU A OE2 1 
ATOM   37    N N   . VAL A 1 12  ? 79.857  4.993   47.380  1.00 97.09  ? 87   VAL A N   1 
ATOM   38    C CA  . VAL A 1 12  ? 79.813  4.521   48.760  1.00 89.47  ? 87   VAL A CA  1 
ATOM   39    C C   . VAL A 1 12  ? 78.692  5.212   49.522  1.00 102.44 ? 87   VAL A C   1 
ATOM   40    O O   . VAL A 1 12  ? 77.948  4.574   50.277  1.00 119.19 ? 87   VAL A O   1 
ATOM   41    C CB  . VAL A 1 12  ? 81.177  4.737   49.440  1.00 82.33  ? 87   VAL A CB  1 
ATOM   42    C CG1 . VAL A 1 12  ? 81.149  4.230   50.869  1.00 102.58 ? 87   VAL A CG1 1 
ATOM   43    C CG2 . VAL A 1 12  ? 82.272  4.044   48.653  1.00 84.29  ? 87   VAL A CG2 1 
ATOM   44    N N   . VAL A 1 13  ? 78.545  6.524   49.333  1.00 97.72  ? 88   VAL A N   1 
ATOM   45    C CA  . VAL A 1 13  ? 77.477  7.240   50.023  1.00 96.71  ? 88   VAL A CA  1 
ATOM   46    C C   . VAL A 1 13  ? 76.114  6.839   49.467  1.00 100.52 ? 88   VAL A C   1 
ATOM   47    O O   . VAL A 1 13  ? 75.136  6.710   50.214  1.00 98.71  ? 88   VAL A O   1 
ATOM   48    C CB  . VAL A 1 13  ? 77.714  8.757   49.934  1.00 87.83  ? 88   VAL A CB  1 
ATOM   49    C CG1 . VAL A 1 13  ? 76.493  9.525   50.410  1.00 88.62  ? 88   VAL A CG1 1 
ATOM   50    C CG2 . VAL A 1 13  ? 78.937  9.133   50.752  1.00 85.91  ? 88   VAL A CG2 1 
ATOM   51    N N   . LYS A 1 14  ? 76.034  6.611   48.154  1.00 101.00 ? 89   LYS A N   1 
ATOM   52    C CA  . LYS A 1 14  ? 74.765  6.274   47.520  1.00 109.88 ? 89   LYS A CA  1 
ATOM   53    C C   . LYS A 1 14  ? 74.212  4.966   48.068  1.00 122.52 ? 89   LYS A C   1 
ATOM   54    O O   . LYS A 1 14  ? 73.096  4.920   48.600  1.00 124.34 ? 89   LYS A O   1 
ATOM   55    C CB  . LYS A 1 14  ? 74.947  6.195   46.001  1.00 100.49 ? 89   LYS A CB  1 
ATOM   56    C CG  . LYS A 1 14  ? 73.672  5.909   45.222  1.00 117.64 ? 89   LYS A CG  1 
ATOM   57    C CD  . LYS A 1 14  ? 73.988  5.387   43.829  1.00 117.41 ? 89   LYS A CD  1 
ATOM   58    C CE  . LYS A 1 14  ? 72.740  4.872   43.130  1.00 119.56 ? 89   LYS A CE  1 
ATOM   59    N NZ  . LYS A 1 14  ? 72.034  3.828   43.924  1.00 112.47 ? 89   LYS A NZ  1 
ATOM   60    N N   . MET A 1 15  ? 74.988  3.886   47.960  1.00 119.30 ? 90   MET A N   1 
ATOM   61    C CA  . MET A 1 15  ? 74.473  2.598   48.409  1.00 132.53 ? 90   MET A CA  1 
ATOM   62    C C   . MET A 1 15  ? 75.525  1.703   49.050  1.00 142.94 ? 90   MET A C   1 
ATOM   63    O O   . MET A 1 15  ? 75.217  0.546   49.358  1.00 152.05 ? 90   MET A O   1 
ATOM   64    C CB  . MET A 1 15  ? 73.760  1.886   47.231  1.00 145.69 ? 90   MET A CB  1 
ATOM   65    C CG  . MET A 1 15  ? 74.576  1.628   45.941  1.00 132.12 ? 90   MET A CG  1 
ATOM   66    S SD  . MET A 1 15  ? 76.173  0.778   45.967  1.00 147.06 ? 90   MET A SD  1 
ATOM   67    C CE  . MET A 1 15  ? 75.730  -0.810  46.661  1.00 159.48 ? 90   MET A CE  1 
ATOM   68    N N   . GLY A 1 16  ? 76.723  2.215   49.320  1.00 142.95 ? 91   GLY A N   1 
ATOM   69    C CA  . GLY A 1 16  ? 77.823  1.398   49.801  1.00 143.87 ? 91   GLY A CA  1 
ATOM   70    C C   . GLY A 1 16  ? 77.564  0.611   51.072  1.00 143.16 ? 91   GLY A C   1 
ATOM   71    O O   . GLY A 1 16  ? 78.352  -0.275  51.419  1.00 140.31 ? 91   GLY A O   1 
ATOM   72    N N   . LYS A 1 17  ? 76.468  0.921   51.770  1.00 135.60 ? 92   LYS A N   1 
ATOM   73    C CA  . LYS A 1 17  ? 76.108  0.252   53.024  1.00 135.79 ? 92   LYS A CA  1 
ATOM   74    C C   . LYS A 1 17  ? 77.253  0.295   54.034  1.00 141.09 ? 92   LYS A C   1 
ATOM   75    O O   . LYS A 1 17  ? 77.427  -0.622  54.841  1.00 140.85 ? 92   LYS A O   1 
ATOM   76    C CB  . LYS A 1 17  ? 75.656  -1.192  52.780  1.00 143.84 ? 92   LYS A CB  1 
ATOM   77    C CG  . LYS A 1 17  ? 74.591  -1.355  51.704  1.00 156.83 ? 92   LYS A CG  1 
ATOM   78    C CD  . LYS A 1 17  ? 73.275  -0.697  52.108  1.00 157.94 ? 92   LYS A CD  1 
ATOM   79    C CE  . LYS A 1 17  ? 72.704  -1.335  53.369  1.00 145.65 ? 92   LYS A CE  1 
ATOM   80    N NZ  . LYS A 1 17  ? 72.255  -2.737  53.132  1.00 125.77 ? 92   LYS A NZ  1 
ATOM   81    N N   . SER A 1 18  ? 78.043  1.363   53.991  1.00 134.44 ? 93   SER A N   1 
ATOM   82    C CA  . SER A 1 18  ? 79.148  1.573   54.913  1.00 111.49 ? 93   SER A CA  1 
ATOM   83    C C   . SER A 1 18  ? 78.821  2.740   55.833  1.00 114.04 ? 93   SER A C   1 
ATOM   84    O O   . SER A 1 18  ? 78.250  3.745   55.395  1.00 126.25 ? 93   SER A O   1 
ATOM   85    C CB  . SER A 1 18  ? 80.452  1.846   54.161  1.00 108.98 ? 93   SER A CB  1 
ATOM   86    O OG  . SER A 1 18  ? 80.678  0.866   53.162  1.00 121.69 ? 93   SER A OG  1 
ATOM   87    N N   . ALA A 1 19  ? 79.173  2.598   57.109  1.00 104.00 ? 94   ALA A N   1 
ATOM   88    C CA  . ALA A 1 19  ? 78.928  3.665   58.069  1.00 102.71 ? 94   ALA A CA  1 
ATOM   89    C C   . ALA A 1 19  ? 79.645  4.937   57.635  1.00 103.57 ? 94   ALA A C   1 
ATOM   90    O O   . ALA A 1 19  ? 80.835  4.911   57.305  1.00 100.45 ? 94   ALA A O   1 
ATOM   91    C CB  . ALA A 1 19  ? 79.391  3.239   59.463  1.00 118.63 ? 94   ALA A CB  1 
ATOM   92    N N   . MET A 1 20  ? 78.906  6.052   57.621  1.00 103.45 ? 95   MET A N   1 
ATOM   93    C CA  . MET A 1 20  ? 79.494  7.335   57.243  1.00 91.47  ? 95   MET A CA  1 
ATOM   94    C C   . MET A 1 20  ? 80.713  7.669   58.090  1.00 90.88  ? 95   MET A C   1 
ATOM   95    O O   . MET A 1 20  ? 81.613  8.382   57.630  1.00 92.20  ? 95   MET A O   1 
ATOM   96    C CB  . MET A 1 20  ? 78.447  8.446   57.354  1.00 79.01  ? 95   MET A CB  1 
ATOM   97    C CG  . MET A 1 20  ? 77.350  8.354   56.313  1.00 85.51  ? 95   MET A CG  1 
ATOM   98    S SD  . MET A 1 20  ? 78.051  8.015   54.690  1.00 94.01  ? 95   MET A SD  1 
ATOM   99    C CE  . MET A 1 20  ? 77.096  6.584   54.195  1.00 98.00  ? 95   MET A CE  1 
ATOM   100   N N   . GLN A 1 21  ? 80.765  7.158   59.322  1.00 92.45  ? 96   GLN A N   1 
ATOM   101   C CA  . GLN A 1 21  ? 81.933  7.367   60.169  1.00 86.67  ? 96   GLN A CA  1 
ATOM   102   C C   . GLN A 1 21  ? 83.170  6.731   59.546  1.00 91.08  ? 96   GLN A C   1 
ATOM   103   O O   . GLN A 1 21  ? 84.243  7.345   59.496  1.00 100.06 ? 96   GLN A O   1 
ATOM   104   C CB  . GLN A 1 21  ? 81.670  6.795   61.566  1.00 81.07  ? 96   GLN A CB  1 
ATOM   105   C CG  . GLN A 1 21  ? 82.908  6.580   62.447  1.00 108.59 ? 96   GLN A CG  1 
ATOM   106   C CD  . GLN A 1 21  ? 83.635  7.867   62.827  1.00 117.54 ? 96   GLN A CD  1 
ATOM   107   O OE1 . GLN A 1 21  ? 83.790  8.780   62.015  1.00 143.83 ? 96   GLN A OE1 1 
ATOM   108   N NE2 . GLN A 1 21  ? 84.093  7.936   64.071  1.00 123.78 ? 96   GLN A NE2 1 
ATOM   109   N N   . SER A 1 22  ? 83.031  5.498   59.053  1.00 90.22  ? 97   SER A N   1 
ATOM   110   C CA  . SER A 1 22  ? 84.151  4.814   58.415  1.00 94.80  ? 97   SER A CA  1 
ATOM   111   C C   . SER A 1 22  ? 84.604  5.557   57.164  1.00 85.84  ? 97   SER A C   1 
ATOM   112   O O   . SER A 1 22  ? 85.806  5.727   56.926  1.00 87.31  ? 97   SER A O   1 
ATOM   113   C CB  . SER A 1 22  ? 83.756  3.377   58.071  1.00 87.90  ? 97   SER A CB  1 
ATOM   114   O OG  . SER A 1 22  ? 83.268  2.695   59.215  1.00 92.67  ? 97   SER A OG  1 
ATOM   115   N N   . VAL A 1 23  ? 83.644  6.002   56.352  1.00 76.96  ? 98   VAL A N   1 
ATOM   116   C CA  . VAL A 1 23  ? 83.960  6.736   55.128  1.00 73.62  ? 98   VAL A CA  1 
ATOM   117   C C   . VAL A 1 23  ? 84.732  8.008   55.458  1.00 78.64  ? 98   VAL A C   1 
ATOM   118   O O   . VAL A 1 23  ? 85.765  8.315   54.844  1.00 87.50  ? 98   VAL A O   1 
ATOM   119   C CB  . VAL A 1 23  ? 82.665  7.043   54.353  1.00 71.51  ? 98   VAL A CB  1 
ATOM   120   C CG1 . VAL A 1 23  ? 82.971  7.791   53.079  1.00 68.01  ? 98   VAL A CG1 1 
ATOM   121   C CG2 . VAL A 1 23  ? 81.904  5.758   54.058  1.00 71.05  ? 98   VAL A CG2 1 
ATOM   122   N N   . VAL A 1 24  ? 84.241  8.761   56.446  1.00 74.94  ? 99   VAL A N   1 
ATOM   123   C CA  . VAL A 1 24  ? 84.891  10.005  56.845  1.00 72.94  ? 99   VAL A CA  1 
ATOM   124   C C   . VAL A 1 24  ? 86.296  9.732   57.369  1.00 82.27  ? 99   VAL A C   1 
ATOM   125   O O   . VAL A 1 24  ? 87.240  10.469  57.060  1.00 79.06  ? 99   VAL A O   1 
ATOM   126   C CB  . VAL A 1 24  ? 84.026  10.742  57.886  1.00 63.75  ? 99   VAL A CB  1 
ATOM   127   C CG1 . VAL A 1 24  ? 84.844  11.774  58.641  1.00 70.65  ? 99   VAL A CG1 1 
ATOM   128   C CG2 . VAL A 1 24  ? 82.823  11.392  57.216  1.00 67.99  ? 99   VAL A CG2 1 
ATOM   129   N N   . ASP A 1 25  ? 86.461  8.670   58.164  1.00 80.58  ? 100  ASP A N   1 
ATOM   130   C CA  . ASP A 1 25  ? 87.782  8.360   58.706  1.00 82.31  ? 100  ASP A CA  1 
ATOM   131   C C   . ASP A 1 25  ? 88.761  7.997   57.598  1.00 88.05  ? 100  ASP A C   1 
ATOM   132   O O   . ASP A 1 25  ? 89.933  8.399   57.636  1.00 83.83  ? 100  ASP A O   1 
ATOM   133   C CB  . ASP A 1 25  ? 87.687  7.223   59.723  1.00 81.32  ? 100  ASP A CB  1 
ATOM   134   C CG  . ASP A 1 25  ? 86.939  7.622   60.979  1.00 88.02  ? 100  ASP A CG  1 
ATOM   135   O OD1 . ASP A 1 25  ? 87.214  8.716   61.518  1.00 93.34  ? 100  ASP A OD1 1 
ATOM   136   O OD2 . ASP A 1 25  ? 86.087  6.833   61.437  1.00 88.14  ? 100  ASP A OD2 1 
ATOM   137   N N   . ASP A 1 26  ? 88.303  7.227   56.608  1.00 78.64  ? 101  ASP A N   1 
ATOM   138   C CA  . ASP A 1 26  ? 89.157  6.919   55.466  1.00 78.58  ? 101  ASP A CA  1 
ATOM   139   C C   . ASP A 1 26  ? 89.563  8.189   54.730  1.00 89.80  ? 101  ASP A C   1 
ATOM   140   O O   . ASP A 1 26  ? 90.730  8.349   54.340  1.00 90.45  ? 101  ASP A O   1 
ATOM   141   C CB  . ASP A 1 26  ? 88.445  5.957   54.514  1.00 81.39  ? 101  ASP A CB  1 
ATOM   142   C CG  . ASP A 1 26  ? 88.221  4.590   55.125  1.00 87.74  ? 101  ASP A CG  1 
ATOM   143   O OD1 . ASP A 1 26  ? 89.198  3.995   55.628  1.00 98.12  ? 101  ASP A OD1 1 
ATOM   144   O OD2 . ASP A 1 26  ? 87.071  4.103   55.091  1.00 91.76  ? 101  ASP A OD2 1 
ATOM   145   N N   . TRP A 1 27  ? 88.614  9.109   54.534  1.00 85.81  ? 102  TRP A N   1 
ATOM   146   C CA  . TRP A 1 27  ? 88.959  10.360  53.866  1.00 86.07  ? 102  TRP A CA  1 
ATOM   147   C C   . TRP A 1 27  ? 89.953  11.168  54.689  1.00 86.08  ? 102  TRP A C   1 
ATOM   148   O O   . TRP A 1 27  ? 90.815  11.850  54.125  1.00 88.58  ? 102  TRP A O   1 
ATOM   149   C CB  . TRP A 1 27  ? 87.709  11.195  53.590  1.00 70.18  ? 102  TRP A CB  1 
ATOM   150   C CG  . TRP A 1 27  ? 88.019  12.440  52.805  1.00 67.08  ? 102  TRP A CG  1 
ATOM   151   C CD1 . TRP A 1 27  ? 87.937  12.591  51.451  1.00 74.83  ? 102  TRP A CD1 1 
ATOM   152   C CD2 . TRP A 1 27  ? 88.487  13.696  53.319  1.00 61.74  ? 102  TRP A CD2 1 
ATOM   153   N NE1 . TRP A 1 27  ? 88.315  13.861  51.091  1.00 78.17  ? 102  TRP A NE1 1 
ATOM   154   C CE2 . TRP A 1 27  ? 88.658  14.559  52.218  1.00 63.72  ? 102  TRP A CE2 1 
ATOM   155   C CE3 . TRP A 1 27  ? 88.773  14.177  54.602  1.00 77.84  ? 102  TRP A CE3 1 
ATOM   156   C CZ2 . TRP A 1 27  ? 89.101  15.871  52.359  1.00 73.94  ? 102  TRP A CZ2 1 
ATOM   157   C CZ3 . TRP A 1 27  ? 89.216  15.478  54.738  1.00 80.23  ? 102  TRP A CZ3 1 
ATOM   158   C CH2 . TRP A 1 27  ? 89.375  16.310  53.623  1.00 86.61  ? 102  TRP A CH2 1 
ATOM   159   N N   . ILE A 1 28  ? 89.850  11.105  56.018  1.00 83.65  ? 103  ILE A N   1 
ATOM   160   C CA  . ILE A 1 28  ? 90.791  11.826  56.872  1.00 86.49  ? 103  ILE A CA  1 
ATOM   161   C C   . ILE A 1 28  ? 92.186  11.230  56.754  1.00 92.59  ? 103  ILE A C   1 
ATOM   162   O O   . ILE A 1 28  ? 93.187  11.958  56.721  1.00 88.10  ? 103  ILE A O   1 
ATOM   163   C CB  . ILE A 1 28  ? 90.301  11.832  58.330  1.00 77.82  ? 103  ILE A CB  1 
ATOM   164   C CG1 . ILE A 1 28  ? 88.998  12.618  58.448  1.00 69.06  ? 103  ILE A CG1 1 
ATOM   165   C CG2 . ILE A 1 28  ? 91.363  12.400  59.259  1.00 74.12  ? 103  ILE A CG2 1 
ATOM   166   C CD1 . ILE A 1 28  ? 88.538  12.777  59.860  1.00 74.86  ? 103  ILE A CD1 1 
ATOM   167   N N   . GLU A 1 29  ? 92.280  9.900   56.708  1.00 93.40  ? 104  GLU A N   1 
ATOM   168   C CA  . GLU A 1 29  ? 93.575  9.270   56.466  1.00 95.30  ? 104  GLU A CA  1 
ATOM   169   C C   . GLU A 1 29  ? 94.155  9.723   55.131  1.00 91.74  ? 104  GLU A C   1 
ATOM   170   O O   . GLU A 1 29  ? 95.349  10.041  55.034  1.00 89.77  ? 104  GLU A O   1 
ATOM   171   C CB  . GLU A 1 29  ? 93.442  7.747   56.505  1.00 93.87  ? 104  GLU A CB  1 
ATOM   172   C CG  . GLU A 1 29  ? 92.841  7.195   57.788  1.00 110.04 ? 104  GLU A CG  1 
ATOM   173   C CD  . GLU A 1 29  ? 93.389  7.869   59.030  1.00 119.99 ? 104  GLU A CD  1 
ATOM   174   O OE1 . GLU A 1 29  ? 94.605  7.749   59.289  1.00 111.03 ? 104  GLU A OE1 1 
ATOM   175   O OE2 . GLU A 1 29  ? 92.599  8.511   59.755  1.00 126.88 ? 104  GLU A OE2 1 
ATOM   176   N N   . SER A 1 30  ? 93.315  9.768   54.093  1.00 86.54  ? 105  SER A N   1 
ATOM   177   C CA  . SER A 1 30  ? 93.773  10.247  52.791  1.00 77.62  ? 105  SER A CA  1 
ATOM   178   C C   . SER A 1 30  ? 94.261  11.690  52.873  1.00 74.34  ? 105  SER A C   1 
ATOM   179   O O   . SER A 1 30  ? 95.275  12.047  52.262  1.00 84.78  ? 105  SER A O   1 
ATOM   180   C CB  . SER A 1 30  ? 92.652  10.117  51.760  1.00 69.19  ? 105  SER A CB  1 
ATOM   181   O OG  . SER A 1 30  ? 93.060  10.615  50.498  1.00 80.71  ? 105  SER A OG  1 
ATOM   182   N N   . TYR A 1 31  ? 93.546  12.531  53.623  1.00 76.76  ? 106  TYR A N   1 
ATOM   183   C CA  . TYR A 1 31  ? 93.971  13.914  53.823  1.00 81.85  ? 106  TYR A CA  1 
ATOM   184   C C   . TYR A 1 31  ? 95.332  13.974  54.503  1.00 84.67  ? 106  TYR A C   1 
ATOM   185   O O   . TYR A 1 31  ? 96.175  14.809  54.154  1.00 76.66  ? 106  TYR A O   1 
ATOM   186   C CB  . TYR A 1 31  ? 92.925  14.661  54.650  1.00 74.56  ? 106  TYR A CB  1 
ATOM   187   C CG  . TYR A 1 31  ? 93.049  16.168  54.617  1.00 71.97  ? 106  TYR A CG  1 
ATOM   188   C CD1 . TYR A 1 31  ? 92.731  16.888  53.474  1.00 78.65  ? 106  TYR A CD1 1 
ATOM   189   C CD2 . TYR A 1 31  ? 93.492  16.871  55.730  1.00 67.62  ? 106  TYR A CD2 1 
ATOM   190   C CE1 . TYR A 1 31  ? 92.841  18.266  53.443  1.00 81.59  ? 106  TYR A CE1 1 
ATOM   191   C CE2 . TYR A 1 31  ? 93.612  18.247  55.706  1.00 69.86  ? 106  TYR A CE2 1 
ATOM   192   C CZ  . TYR A 1 31  ? 93.283  18.940  54.563  1.00 76.55  ? 106  TYR A CZ  1 
ATOM   193   O OH  . TYR A 1 31  ? 93.399  20.311  54.541  1.00 75.98  ? 106  TYR A OH  1 
ATOM   194   N N   . LYS A 1 32  ? 95.559  13.098  55.484  1.00 80.61  ? 107  LYS A N   1 
ATOM   195   C CA  . LYS A 1 32  ? 96.865  13.031  56.131  1.00 82.69  ? 107  LYS A CA  1 
ATOM   196   C C   . LYS A 1 32  ? 97.956  12.663  55.133  1.00 95.36  ? 107  LYS A C   1 
ATOM   197   O O   . LYS A 1 32  ? 99.045  13.250  55.147  1.00 116.25 ? 107  LYS A O   1 
ATOM   198   C CB  . LYS A 1 32  ? 96.841  12.023  57.279  1.00 94.98  ? 107  LYS A CB  1 
ATOM   199   C CG  . LYS A 1 32  ? 95.841  12.327  58.374  1.00 73.82  ? 107  LYS A CG  1 
ATOM   200   C CD  . LYS A 1 32  ? 95.759  11.165  59.346  1.00 93.86  ? 107  LYS A CD  1 
ATOM   201   C CE  . LYS A 1 32  ? 94.773  11.437  60.464  1.00 90.35  ? 107  LYS A CE  1 
ATOM   202   N NZ  . LYS A 1 32  ? 94.685  10.276  61.391  1.00 112.93 ? 107  LYS A NZ  1 
ATOM   203   N N   . HIS A 1 33  ? 97.687  11.688  54.262  1.00 82.17  ? 108  HIS A N   1 
ATOM   204   C CA  . HIS A 1 33  ? 98.695  11.285  53.283  1.00 80.75  ? 108  HIS A CA  1 
ATOM   205   C C   . HIS A 1 33  ? 98.946  12.390  52.263  1.00 94.31  ? 108  HIS A C   1 
ATOM   206   O O   . HIS A 1 33  ? 100.090 12.812  52.059  1.00 105.19 ? 108  HIS A O   1 
ATOM   207   C CB  . HIS A 1 33  ? 98.271  9.990   52.588  1.00 84.75  ? 108  HIS A CB  1 
ATOM   208   C CG  . HIS A 1 33  ? 99.168  9.594   51.456  1.00 105.76 ? 108  HIS A CG  1 
ATOM   209   N ND1 . HIS A 1 33  ? 98.740  9.547   50.147  1.00 117.60 ? 108  HIS A ND1 1 
ATOM   210   C CD2 . HIS A 1 33  ? 100.475 9.237   51.437  1.00 119.67 ? 108  HIS A CD2 1 
ATOM   211   C CE1 . HIS A 1 33  ? 99.741  9.171   49.370  1.00 121.30 ? 108  HIS A CE1 1 
ATOM   212   N NE2 . HIS A 1 33  ? 100.805 8.977   50.128  1.00 131.80 ? 108  HIS A NE2 1 
ATOM   213   N N   . ASP A 1 34  ? 97.889  12.871  51.612  1.00 92.22  ? 109  ASP A N   1 
ATOM   214   C CA  . ASP A 1 34  ? 97.989  13.977  50.665  1.00 82.96  ? 109  ASP A CA  1 
ATOM   215   C C   . ASP A 1 34  ? 96.734  14.824  50.790  1.00 83.89  ? 109  ASP A C   1 
ATOM   216   O O   . ASP A 1 34  ? 95.635  14.350  50.487  1.00 86.42  ? 109  ASP A O   1 
ATOM   217   C CB  . ASP A 1 34  ? 98.160  13.468  49.226  1.00 90.43  ? 109  ASP A CB  1 
ATOM   218   C CG  . ASP A 1 34  ? 98.443  14.590  48.238  1.00 97.39  ? 109  ASP A CG  1 
ATOM   219   O OD1 . ASP A 1 34  ? 97.641  15.544  48.146  1.00 99.05  ? 109  ASP A OD1 1 
ATOM   220   O OD2 . ASP A 1 34  ? 99.481  14.516  47.550  1.00 89.17  ? 109  ASP A OD2 1 
ATOM   221   N N   . ARG A 1 35  ? 96.902  16.074  51.224  1.00 81.76  ? 110  ARG A N   1 
ATOM   222   C CA  . ARG A 1 35  ? 95.754  16.942  51.454  1.00 79.99  ? 110  ARG A CA  1 
ATOM   223   C C   . ARG A 1 35  ? 95.072  17.321  50.144  1.00 89.50  ? 110  ARG A C   1 
ATOM   224   O O   . ARG A 1 35  ? 93.837  17.327  50.057  1.00 98.77  ? 110  ARG A O   1 
ATOM   225   C CB  . ARG A 1 35  ? 96.201  18.189  52.222  1.00 68.74  ? 110  ARG A CB  1 
ATOM   226   C CG  . ARG A 1 35  ? 96.845  17.861  53.566  1.00 80.51  ? 110  ARG A CG  1 
ATOM   227   C CD  . ARG A 1 35  ? 97.761  18.968  54.077  1.00 99.88  ? 110  ARG A CD  1 
ATOM   228   N NE  . ARG A 1 35  ? 97.052  20.059  54.733  1.00 98.18  ? 110  ARG A NE  1 
ATOM   229   C CZ  . ARG A 1 35  ? 97.216  21.343  54.442  1.00 96.26  ? 110  ARG A CZ  1 
ATOM   230   N NH1 . ARG A 1 35  ? 98.028  21.734  53.473  1.00 87.69  ? 110  ARG A NH1 1 
ATOM   231   N NH2 . ARG A 1 35  ? 96.559  22.257  55.149  1.00 113.88 ? 110  ARG A NH2 1 
ATOM   232   N N   . ASP A 1 36  ? 95.862  17.621  49.108  1.00 72.59  ? 111  ASP A N   1 
ATOM   233   C CA  . ASP A 1 36  ? 95.291  18.034  47.830  1.00 78.87  ? 111  ASP A CA  1 
ATOM   234   C C   . ASP A 1 36  ? 94.488  16.908  47.189  1.00 82.23  ? 111  ASP A C   1 
ATOM   235   O O   . ASP A 1 36  ? 93.424  17.149  46.604  1.00 93.65  ? 111  ASP A O   1 
ATOM   236   C CB  . ASP A 1 36  ? 96.401  18.503  46.890  1.00 81.97  ? 111  ASP A CB  1 
ATOM   237   C CG  . ASP A 1 36  ? 97.464  19.320  47.602  1.00 100.31 ? 111  ASP A CG  1 
ATOM   238   O OD1 . ASP A 1 36  ? 97.143  20.431  48.077  1.00 90.47  ? 111  ASP A OD1 1 
ATOM   239   O OD2 . ASP A 1 36  ? 98.619  18.852  47.688  1.00 116.16 ? 111  ASP A OD2 1 
ATOM   240   N N   . ILE A 1 37  ? 94.976  15.671  47.294  1.00 78.78  ? 112  ILE A N   1 
ATOM   241   C CA  . ILE A 1 37  ? 94.288  14.543  46.671  1.00 82.21  ? 112  ILE A CA  1 
ATOM   242   C C   . ILE A 1 37  ? 92.936  14.315  47.339  1.00 84.27  ? 112  ILE A C   1 
ATOM   243   O O   . ILE A 1 37  ? 91.912  14.134  46.667  1.00 92.08  ? 112  ILE A O   1 
ATOM   244   C CB  . ILE A 1 37  ? 95.175  13.283  46.721  1.00 83.92  ? 112  ILE A CB  1 
ATOM   245   C CG1 . ILE A 1 37  ? 95.956  13.118  45.414  1.00 83.05  ? 112  ILE A CG1 1 
ATOM   246   C CG2 . ILE A 1 37  ? 94.341  12.033  46.976  1.00 84.35  ? 112  ILE A CG2 1 
ATOM   247   C CD1 . ILE A 1 37  ? 96.728  14.350  44.983  1.00 84.89  ? 112  ILE A CD1 1 
ATOM   248   N N   . ALA A 1 38  ? 92.910  14.344  48.674  1.00 79.30  ? 113  ALA A N   1 
ATOM   249   C CA  . ALA A 1 38  ? 91.652  14.169  49.390  1.00 82.53  ? 113  ALA A CA  1 
ATOM   250   C C   . ALA A 1 38  ? 90.699  15.324  49.119  1.00 81.34  ? 113  ALA A C   1 
ATOM   251   O O   . ALA A 1 38  ? 89.483  15.123  49.008  1.00 82.48  ? 113  ALA A O   1 
ATOM   252   C CB  . ALA A 1 38  ? 91.912  14.029  50.888  1.00 76.99  ? 113  ALA A CB  1 
ATOM   253   N N   . LEU A 1 39  ? 91.230  16.545  49.002  1.00 71.68  ? 114  LEU A N   1 
ATOM   254   C CA  . LEU A 1 39  ? 90.375  17.684  48.682  1.00 81.89  ? 114  LEU A CA  1 
ATOM   255   C C   . LEU A 1 39  ? 89.754  17.535  47.300  1.00 82.82  ? 114  LEU A C   1 
ATOM   256   O O   . LEU A 1 39  ? 88.577  17.860  47.100  1.00 79.67  ? 114  LEU A O   1 
ATOM   257   C CB  . LEU A 1 39  ? 91.168  18.987  48.774  1.00 70.05  ? 114  LEU A CB  1 
ATOM   258   C CG  . LEU A 1 39  ? 91.476  19.471  50.188  1.00 68.21  ? 114  LEU A CG  1 
ATOM   259   C CD1 . LEU A 1 39  ? 91.897  20.928  50.160  1.00 70.94  ? 114  LEU A CD1 1 
ATOM   260   C CD2 . LEU A 1 39  ? 90.268  19.271  51.083  1.00 67.93  ? 114  LEU A CD2 1 
ATOM   261   N N   . LEU A 1 40  ? 90.534  17.054  46.330  1.00 82.83  ? 115  LEU A N   1 
ATOM   262   C CA  . LEU A 1 40  ? 89.988  16.815  44.998  1.00 80.40  ? 115  LEU A CA  1 
ATOM   263   C C   . LEU A 1 40  ? 88.918  15.732  45.033  1.00 85.37  ? 115  LEU A C   1 
ATOM   264   O O   . LEU A 1 40  ? 87.884  15.847  44.360  1.00 89.68  ? 115  LEU A O   1 
ATOM   265   C CB  . LEU A 1 40  ? 91.109  16.435  44.031  1.00 84.11  ? 115  LEU A CB  1 
ATOM   266   C CG  . LEU A 1 40  ? 90.703  16.334  42.559  1.00 81.68  ? 115  LEU A CG  1 
ATOM   267   C CD1 . LEU A 1 40  ? 90.268  17.692  42.030  1.00 90.49  ? 115  LEU A CD1 1 
ATOM   268   C CD2 . LEU A 1 40  ? 91.835  15.762  41.719  1.00 97.62  ? 115  LEU A CD2 1 
ATOM   269   N N   . ASP A 1 41  ? 89.147  14.673  45.814  1.00 82.14  ? 116  ASP A N   1 
ATOM   270   C CA  . ASP A 1 41  ? 88.132  13.631  45.945  1.00 83.17  ? 116  ASP A CA  1 
ATOM   271   C C   . ASP A 1 41  ? 86.854  14.180  46.567  1.00 81.32  ? 116  ASP A C   1 
ATOM   272   O O   . ASP A 1 41  ? 85.752  13.806  46.161  1.00 72.23  ? 116  ASP A O   1 
ATOM   273   C CB  . ASP A 1 41  ? 88.668  12.459  46.766  1.00 86.08  ? 116  ASP A CB  1 
ATOM   274   C CG  . ASP A 1 41  ? 89.866  11.795  46.120  1.00 89.75  ? 116  ASP A CG  1 
ATOM   275   O OD1 . ASP A 1 41  ? 89.796  11.489  44.910  1.00 90.06  ? 116  ASP A OD1 1 
ATOM   276   O OD2 . ASP A 1 41  ? 90.870  11.565  46.825  1.00 94.77  ? 116  ASP A OD2 1 
ATOM   277   N N   . LEU A 1 42  ? 86.983  15.086  47.539  1.00 76.87  ? 117  LEU A N   1 
ATOM   278   C CA  . LEU A 1 42  ? 85.804  15.673  48.174  1.00 73.86  ? 117  LEU A CA  1 
ATOM   279   C C   . LEU A 1 42  ? 85.050  16.584  47.208  1.00 78.58  ? 117  LEU A C   1 
ATOM   280   O O   . LEU A 1 42  ? 83.808  16.578  47.165  1.00 76.27  ? 117  LEU A O   1 
ATOM   281   C CB  . LEU A 1 42  ? 86.232  16.442  49.425  1.00 63.61  ? 117  LEU A CB  1 
ATOM   282   C CG  . LEU A 1 42  ? 85.199  16.833  50.479  1.00 75.54  ? 117  LEU A CG  1 
ATOM   283   C CD1 . LEU A 1 42  ? 84.365  15.629  50.883  1.00 72.01  ? 117  LEU A CD1 1 
ATOM   284   C CD2 . LEU A 1 42  ? 85.909  17.425  51.686  1.00 62.05  ? 117  LEU A CD2 1 
ATOM   285   N N   . ILE A 1 43  ? 85.789  17.386  46.439  1.00 68.80  ? 118  ILE A N   1 
ATOM   286   C CA  . ILE A 1 43  ? 85.179  18.234  45.420  1.00 62.96  ? 118  ILE A CA  1 
ATOM   287   C C   . ILE A 1 43  ? 84.385  17.383  44.437  1.00 68.37  ? 118  ILE A C   1 
ATOM   288   O O   . ILE A 1 43  ? 83.214  17.662  44.148  1.00 72.76  ? 118  ILE A O   1 
ATOM   289   C CB  . ILE A 1 43  ? 86.259  19.062  44.702  1.00 62.75  ? 118  ILE A CB  1 
ATOM   290   C CG1 . ILE A 1 43  ? 86.827  20.126  45.641  1.00 51.75  ? 118  ILE A CG1 1 
ATOM   291   C CG2 . ILE A 1 43  ? 85.701  19.692  43.434  1.00 65.63  ? 118  ILE A CG2 1 
ATOM   292   C CD1 . ILE A 1 43  ? 87.926  20.945  45.022  1.00 45.48  ? 118  ILE A CD1 1 
ATOM   293   N N   . ASN A 1 44  ? 85.011  16.322  43.918  1.00 64.50  ? 119  ASN A N   1 
ATOM   294   C CA  . ASN A 1 44  ? 84.315  15.433  42.994  1.00 71.59  ? 119  ASN A CA  1 
ATOM   295   C C   . ASN A 1 44  ? 83.166  14.702  43.675  1.00 76.67  ? 119  ASN A C   1 
ATOM   296   O O   . ASN A 1 44  ? 82.184  14.351  43.017  1.00 83.47  ? 119  ASN A O   1 
ATOM   297   C CB  . ASN A 1 44  ? 85.294  14.432  42.382  1.00 70.95  ? 119  ASN A CB  1 
ATOM   298   C CG  . ASN A 1 44  ? 86.219  15.069  41.366  1.00 82.37  ? 119  ASN A CG  1 
ATOM   299   O OD1 . ASN A 1 44  ? 85.772  15.601  40.349  1.00 79.60  ? 119  ASN A OD1 1 
ATOM   300   N ND2 . ASN A 1 44  ? 87.518  15.019  41.636  1.00 89.88  ? 119  ASN A ND2 1 
ATOM   301   N N   . PHE A 1 45  ? 83.266  14.461  44.983  1.00 66.34  ? 120  PHE A N   1 
ATOM   302   C CA  . PHE A 1 45  ? 82.142  13.896  45.721  1.00 74.20  ? 120  PHE A CA  1 
ATOM   303   C C   . PHE A 1 45  ? 80.930  14.810  45.637  1.00 72.46  ? 120  PHE A C   1 
ATOM   304   O O   . PHE A 1 45  ? 79.826  14.373  45.294  1.00 66.18  ? 120  PHE A O   1 
ATOM   305   C CB  . PHE A 1 45  ? 82.539  13.666  47.180  1.00 73.14  ? 120  PHE A CB  1 
ATOM   306   C CG  . PHE A 1 45  ? 81.373  13.424  48.097  1.00 68.16  ? 120  PHE A CG  1 
ATOM   307   C CD1 . PHE A 1 45  ? 80.685  12.221  48.068  1.00 69.05  ? 120  PHE A CD1 1 
ATOM   308   C CD2 . PHE A 1 45  ? 80.954  14.408  48.979  1.00 66.38  ? 120  PHE A CD2 1 
ATOM   309   C CE1 . PHE A 1 45  ? 79.614  11.999  48.912  1.00 68.47  ? 120  PHE A CE1 1 
ATOM   310   C CE2 . PHE A 1 45  ? 79.880  14.194  49.822  1.00 65.88  ? 120  PHE A CE2 1 
ATOM   311   C CZ  . PHE A 1 45  ? 79.209  12.987  49.788  1.00 68.51  ? 120  PHE A CZ  1 
ATOM   312   N N   . PHE A 1 46  ? 81.124  16.094  45.943  1.00 69.47  ? 121  PHE A N   1 
ATOM   313   C CA  . PHE A 1 46  ? 80.011  17.036  45.843  1.00 65.54  ? 121  PHE A CA  1 
ATOM   314   C C   . PHE A 1 46  ? 79.518  17.174  44.406  1.00 71.45  ? 121  PHE A C   1 
ATOM   315   O O   . PHE A 1 46  ? 78.315  17.339  44.171  1.00 68.67  ? 121  PHE A O   1 
ATOM   316   C CB  . PHE A 1 46  ? 80.405  18.396  46.412  1.00 59.00  ? 121  PHE A CB  1 
ATOM   317   C CG  . PHE A 1 46  ? 80.501  18.413  47.904  1.00 62.38  ? 121  PHE A CG  1 
ATOM   318   C CD1 . PHE A 1 46  ? 79.406  18.072  48.681  1.00 62.67  ? 121  PHE A CD1 1 
ATOM   319   C CD2 . PHE A 1 46  ? 81.682  18.757  48.530  1.00 67.88  ? 121  PHE A CD2 1 
ATOM   320   C CE1 . PHE A 1 46  ? 79.488  18.077  50.057  1.00 65.15  ? 121  PHE A CE1 1 
ATOM   321   C CE2 . PHE A 1 46  ? 81.772  18.765  49.908  1.00 62.23  ? 121  PHE A CE2 1 
ATOM   322   C CZ  . PHE A 1 46  ? 80.673  18.425  50.673  1.00 62.60  ? 121  PHE A CZ  1 
ATOM   323   N N   . ILE A 1 47  ? 80.427  17.104  43.431  1.00 73.54  ? 122  ILE A N   1 
ATOM   324   C CA  . ILE A 1 47  ? 80.009  17.205  42.031  1.00 71.31  ? 122  ILE A CA  1 
ATOM   325   C C   . ILE A 1 47  ? 79.136  16.015  41.642  1.00 71.50  ? 122  ILE A C   1 
ATOM   326   O O   . ILE A 1 47  ? 78.069  16.178  41.039  1.00 77.85  ? 122  ILE A O   1 
ATOM   327   C CB  . ILE A 1 47  ? 81.232  17.341  41.106  1.00 62.74  ? 122  ILE A CB  1 
ATOM   328   C CG1 . ILE A 1 47  ? 82.017  18.605  41.450  1.00 61.99  ? 122  ILE A CG1 1 
ATOM   329   C CG2 . ILE A 1 47  ? 80.803  17.364  39.655  1.00 69.34  ? 122  ILE A CG2 1 
ATOM   330   C CD1 . ILE A 1 47  ? 81.260  19.881  41.152  1.00 68.84  ? 122  ILE A CD1 1 
ATOM   331   N N   . GLN A 1 48  ? 79.574  14.802  41.985  1.00 69.52  ? 123  GLN A N   1 
ATOM   332   C CA  . GLN A 1 48  ? 78.805  13.607  41.653  1.00 74.46  ? 123  GLN A CA  1 
ATOM   333   C C   . GLN A 1 48  ? 77.472  13.580  42.390  1.00 70.27  ? 123  GLN A C   1 
ATOM   334   O O   . GLN A 1 48  ? 76.468  13.099  41.850  1.00 76.69  ? 123  GLN A O   1 
ATOM   335   C CB  . GLN A 1 48  ? 79.610  12.349  41.978  1.00 79.06  ? 123  GLN A CB  1 
ATOM   336   C CG  . GLN A 1 48  ? 80.504  11.833  40.857  1.00 75.15  ? 123  GLN A CG  1 
ATOM   337   C CD  . GLN A 1 48  ? 81.967  12.161  41.080  1.00 77.69  ? 123  GLN A CD  1 
ATOM   338   O OE1 . GLN A 1 48  ? 82.568  11.731  42.064  1.00 86.04  ? 123  GLN A OE1 1 
ATOM   339   N NE2 . GLN A 1 48  ? 82.552  12.920  40.158  1.00 79.77  ? 123  GLN A NE2 1 
ATOM   340   N N   . CYS A 1 49  ? 77.443  14.076  43.632  1.00 67.50  ? 124  CYS A N   1 
ATOM   341   C CA  . CYS A 1 49  ? 76.189  14.107  44.380  1.00 64.50  ? 124  CYS A CA  1 
ATOM   342   C C   . CYS A 1 49  ? 75.149  14.985  43.700  1.00 73.44  ? 124  CYS A C   1 
ATOM   343   O O   . CYS A 1 49  ? 73.943  14.760  43.866  1.00 72.73  ? 124  CYS A O   1 
ATOM   344   C CB  . CYS A 1 49  ? 76.431  14.589  45.811  1.00 74.20  ? 124  CYS A CB  1 
ATOM   345   S SG  . CYS A 1 49  ? 77.319  13.422  46.860  1.00 67.82  ? 124  CYS A SG  1 
ATOM   346   N N   . SER A 1 50  ? 75.588  15.988  42.941  1.00 80.23  ? 125  SER A N   1 
ATOM   347   C CA  . SER A 1 50  ? 74.673  16.785  42.137  1.00 81.39  ? 125  SER A CA  1 
ATOM   348   C C   . SER A 1 50  ? 74.180  16.044  40.902  1.00 75.96  ? 125  SER A C   1 
ATOM   349   O O   . SER A 1 50  ? 73.260  16.528  40.234  1.00 84.29  ? 125  SER A O   1 
ATOM   350   C CB  . SER A 1 50  ? 75.346  18.094  41.715  1.00 72.30  ? 125  SER A CB  1 
ATOM   351   O OG  . SER A 1 50  ? 75.974  18.723  42.818  1.00 81.77  ? 125  SER A OG  1 
ATOM   352   N N   . GLY A 1 51  ? 74.762  14.888  40.588  1.00 65.20  ? 126  GLY A N   1 
ATOM   353   C CA  . GLY A 1 51  ? 74.416  14.124  39.413  1.00 76.89  ? 126  GLY A CA  1 
ATOM   354   C C   . GLY A 1 51  ? 75.410  14.240  38.276  1.00 84.65  ? 126  GLY A C   1 
ATOM   355   O O   . GLY A 1 51  ? 75.357  13.433  37.340  1.00 87.91  ? 126  GLY A O   1 
ATOM   356   N N   . CYS A 1 52  ? 76.313  15.218  38.339  1.00 86.11  ? 127  CYS A N   1 
ATOM   357   C CA  . CYS A 1 52  ? 77.271  15.433  37.262  1.00 81.26  ? 127  CYS A CA  1 
ATOM   358   C C   . CYS A 1 52  ? 78.202  14.237  37.118  1.00 80.47  ? 127  CYS A C   1 
ATOM   359   O O   . CYS A 1 52  ? 78.770  13.753  38.101  1.00 79.77  ? 127  CYS A O   1 
ATOM   360   C CB  . CYS A 1 52  ? 78.076  16.704  37.522  1.00 70.60  ? 127  CYS A CB  1 
ATOM   361   S SG  . CYS A 1 52  ? 79.121  17.218  36.144  1.00 104.98 ? 127  CYS A SG  1 
ATOM   362   N N   . LYS A 1 53  ? 78.354  13.765  35.884  1.00 90.50  ? 128  LYS A N   1 
ATOM   363   C CA  . LYS A 1 53  ? 79.204  12.622  35.588  1.00 97.03  ? 128  LYS A CA  1 
ATOM   364   C C   . LYS A 1 53  ? 80.636  13.014  35.250  1.00 90.58  ? 128  LYS A C   1 
ATOM   365   O O   . LYS A 1 53  ? 81.477  12.126  35.073  1.00 101.97 ? 128  LYS A O   1 
ATOM   366   C CB  . LYS A 1 53  ? 78.602  11.810  34.437  1.00 89.98  ? 128  LYS A CB  1 
ATOM   367   C CG  . LYS A 1 53  ? 77.658  10.712  34.900  1.00 95.74  ? 128  LYS A CG  1 
ATOM   368   C CD  . LYS A 1 53  ? 76.416  10.622  34.030  1.00 105.49 ? 128  LYS A CD  1 
ATOM   369   C CE  . LYS A 1 53  ? 75.419  11.709  34.393  1.00 111.74 ? 128  LYS A CE  1 
ATOM   370   N NZ  . LYS A 1 53  ? 74.169  11.623  33.591  1.00 127.23 ? 128  LYS A NZ  1 
ATOM   371   N N   . GLY A 1 54  ? 80.933  14.309  35.156  1.00 73.30  ? 129  GLY A N   1 
ATOM   372   C CA  . GLY A 1 54  ? 82.291  14.741  34.906  1.00 81.30  ? 129  GLY A CA  1 
ATOM   373   C C   . GLY A 1 54  ? 83.152  14.683  36.155  1.00 91.66  ? 129  GLY A C   1 
ATOM   374   O O   . GLY A 1 54  ? 82.681  14.439  37.264  1.00 93.34  ? 129  GLY A O   1 
ATOM   375   N N   . VAL A 1 55  ? 84.445  14.930  35.961  1.00 93.90  ? 130  VAL A N   1 
ATOM   376   C CA  . VAL A 1 55  ? 85.434  14.849  37.030  1.00 85.86  ? 130  VAL A CA  1 
ATOM   377   C C   . VAL A 1 55  ? 86.322  16.084  36.977  1.00 83.87  ? 130  VAL A C   1 
ATOM   378   O O   . VAL A 1 55  ? 86.746  16.509  35.897  1.00 84.55  ? 130  VAL A O   1 
ATOM   379   C CB  . VAL A 1 55  ? 86.283  13.564  36.921  1.00 80.98  ? 130  VAL A CB  1 
ATOM   380   C CG1 . VAL A 1 55  ? 87.393  13.565  37.959  1.00 93.03  ? 130  VAL A CG1 1 
ATOM   381   C CG2 . VAL A 1 55  ? 85.405  12.333  37.083  1.00 88.35  ? 130  VAL A CG2 1 
ATOM   382   N N   . VAL A 1 56  ? 86.602  16.658  38.144  1.00 84.65  ? 131  VAL A N   1 
ATOM   383   C CA  . VAL A 1 56  ? 87.452  17.839  38.231  1.00 82.35  ? 131  VAL A CA  1 
ATOM   384   C C   . VAL A 1 56  ? 88.911  17.402  38.270  1.00 90.03  ? 131  VAL A C   1 
ATOM   385   O O   . VAL A 1 56  ? 89.285  16.515  39.046  1.00 81.58  ? 131  VAL A O   1 
ATOM   386   C CB  . VAL A 1 56  ? 87.090  18.679  39.465  1.00 73.05  ? 131  VAL A CB  1 
ATOM   387   C CG1 . VAL A 1 56  ? 87.967  19.918  39.530  1.00 70.67  ? 131  VAL A CG1 1 
ATOM   388   C CG2 . VAL A 1 56  ? 85.620  19.059  39.427  1.00 78.62  ? 131  VAL A CG2 1 
ATOM   389   N N   . THR A 1 57  ? 89.738  18.023  37.433  1.00 93.26  ? 132  THR A N   1 
ATOM   390   C CA  . THR A 1 57  ? 91.151  17.680  37.375  1.00 89.77  ? 132  THR A CA  1 
ATOM   391   C C   . THR A 1 57  ? 91.928  18.380  38.488  1.00 94.78  ? 132  THR A C   1 
ATOM   392   O O   . THR A 1 57  ? 91.492  19.391  39.048  1.00 98.66  ? 132  THR A O   1 
ATOM   393   C CB  . THR A 1 57  ? 91.745  18.060  36.020  1.00 84.15  ? 132  THR A CB  1 
ATOM   394   O OG1 . THR A 1 57  ? 92.024  19.466  35.996  1.00 89.87  ? 132  THR A OG1 1 
ATOM   395   C CG2 . THR A 1 57  ? 90.774  17.720  34.899  1.00 88.79  ? 132  THR A CG2 1 
ATOM   396   N N   . ALA A 1 58  ? 93.101  17.824  38.803  1.00 87.17  ? 133  ALA A N   1 
ATOM   397   C CA  . ALA A 1 58  ? 93.974  18.448  39.793  1.00 89.55  ? 133  ALA A CA  1 
ATOM   398   C C   . ALA A 1 58  ? 94.478  19.804  39.322  1.00 94.81  ? 133  ALA A C   1 
ATOM   399   O O   . ALA A 1 58  ? 94.643  20.720  40.136  1.00 86.35  ? 133  ALA A O   1 
ATOM   400   C CB  . ALA A 1 58  ? 95.149  17.526  40.110  1.00 104.79 ? 133  ALA A CB  1 
ATOM   401   N N   . GLU A 1 59  ? 94.720  19.953  38.018  1.00 100.52 ? 134  GLU A N   1 
ATOM   402   C CA  . GLU A 1 59  ? 95.096  21.256  37.482  1.00 109.84 ? 134  GLU A CA  1 
ATOM   403   C C   . GLU A 1 59  ? 93.961  22.256  37.651  1.00 101.48 ? 134  GLU A C   1 
ATOM   404   O O   . GLU A 1 59  ? 94.199  23.438  37.928  1.00 97.40  ? 134  GLU A O   1 
ATOM   405   C CB  . GLU A 1 59  ? 95.482  21.126  36.009  1.00 105.57 ? 134  GLU A CB  1 
ATOM   406   C CG  . GLU A 1 59  ? 96.921  20.690  35.769  1.00 116.61 ? 134  GLU A CG  1 
ATOM   407   C CD  . GLU A 1 59  ? 97.927  21.751  36.170  1.00 128.75 ? 134  GLU A CD  1 
ATOM   408   O OE1 . GLU A 1 59  ? 97.898  22.852  35.579  1.00 130.11 ? 134  GLU A OE1 1 
ATOM   409   O OE2 . GLU A 1 59  ? 98.751  21.483  37.071  1.00 127.59 ? 134  GLU A OE2 1 
ATOM   410   N N   . MET A 1 60  ? 92.718  21.795  37.481  1.00 89.14  ? 135  MET A N   1 
ATOM   411   C CA  . MET A 1 60  ? 91.558  22.647  37.721  1.00 87.97  ? 135  MET A CA  1 
ATOM   412   C C   . MET A 1 60  ? 91.544  23.152  39.157  1.00 93.18  ? 135  MET A C   1 
ATOM   413   O O   . MET A 1 60  ? 91.421  24.357  39.408  1.00 99.18  ? 135  MET A O   1 
ATOM   414   C CB  . MET A 1 60  ? 90.273  21.872  37.422  1.00 88.33  ? 135  MET A CB  1 
ATOM   415   C CG  . MET A 1 60  ? 89.853  21.875  35.966  1.00 74.83  ? 135  MET A CG  1 
ATOM   416   S SD  . MET A 1 60  ? 88.469  20.778  35.594  1.00 87.64  ? 135  MET A SD  1 
ATOM   417   C CE  . MET A 1 60  ? 88.729  20.477  33.848  1.00 104.68 ? 135  MET A CE  1 
ATOM   418   N N   . PHE A 1 61  ? 91.671  22.233  40.115  1.00 93.57  ? 136  PHE A N   1 
ATOM   419   C CA  . PHE A 1 61  ? 91.679  22.598  41.526  1.00 86.42  ? 136  PHE A CA  1 
ATOM   420   C C   . PHE A 1 61  ? 92.865  23.494  41.867  1.00 96.97  ? 136  PHE A C   1 
ATOM   421   O O   . PHE A 1 61  ? 92.779  24.318  42.786  1.00 96.03  ? 136  PHE A O   1 
ATOM   422   C CB  . PHE A 1 61  ? 91.683  21.318  42.365  1.00 70.29  ? 136  PHE A CB  1 
ATOM   423   C CG  . PHE A 1 61  ? 91.970  21.530  43.822  1.00 78.88  ? 136  PHE A CG  1 
ATOM   424   C CD1 . PHE A 1 61  ? 91.137  22.309  44.604  1.00 84.23  ? 136  PHE A CD1 1 
ATOM   425   C CD2 . PHE A 1 61  ? 93.059  20.916  44.416  1.00 98.69  ? 136  PHE A CD2 1 
ATOM   426   C CE1 . PHE A 1 61  ? 91.396  22.491  45.950  1.00 80.37  ? 136  PHE A CE1 1 
ATOM   427   C CE2 . PHE A 1 61  ? 93.324  21.093  45.760  1.00 99.66  ? 136  PHE A CE2 1 
ATOM   428   C CZ  . PHE A 1 61  ? 92.491  21.882  46.528  1.00 85.79  ? 136  PHE A CZ  1 
ATOM   429   N N   . ARG A 1 62  ? 93.969  23.368  41.125  1.00 104.15 ? 137  ARG A N   1 
ATOM   430   C CA  . ARG A 1 62  ? 95.160  24.157  41.419  1.00 115.98 ? 137  ARG A CA  1 
ATOM   431   C C   . ARG A 1 62  ? 95.059  25.577  40.868  1.00 126.24 ? 137  ARG A C   1 
ATOM   432   O O   . ARG A 1 62  ? 95.488  26.530  41.528  1.00 131.77 ? 137  ARG A O   1 
ATOM   433   C CB  . ARG A 1 62  ? 96.399  23.459  40.855  1.00 115.18 ? 137  ARG A CB  1 
ATOM   434   C CG  . ARG A 1 62  ? 97.717  23.982  41.407  1.00 121.78 ? 137  ARG A CG  1 
ATOM   435   C CD  . ARG A 1 62  ? 98.895  23.110  40.985  1.00 137.35 ? 137  ARG A CD  1 
ATOM   436   N NE  . ARG A 1 62  ? 98.796  21.748  41.496  1.00 154.01 ? 137  ARG A NE  1 
ATOM   437   C CZ  . ARG A 1 62  ? 98.449  20.694  40.770  1.00 165.20 ? 137  ARG A CZ  1 
ATOM   438   N NH1 . ARG A 1 62  ? 98.165  20.803  39.483  1.00 175.93 ? 137  ARG A NH1 1 
ATOM   439   N NH2 . ARG A 1 62  ? 98.387  19.499  41.351  1.00 173.28 ? 137  ARG A NH2 1 
ATOM   440   N N   . HIS A 1 63  ? 94.503  25.740  39.673  1.00 115.09 ? 138  HIS A N   1 
ATOM   441   C CA  . HIS A 1 63  ? 94.519  27.041  39.009  1.00 119.17 ? 138  HIS A CA  1 
ATOM   442   C C   . HIS A 1 63  ? 93.138  27.529  38.601  1.00 117.61 ? 138  HIS A C   1 
ATOM   443   O O   . HIS A 1 63  ? 92.844  28.715  38.753  1.00 119.92 ? 138  HIS A O   1 
ATOM   444   C CB  . HIS A 1 63  ? 95.422  26.975  37.763  1.00 118.90 ? 138  HIS A CB  1 
ATOM   445   C CG  . HIS A 1 63  ? 96.788  26.426  38.031  1.00 127.06 ? 138  HIS A CG  1 
ATOM   446   N ND1 . HIS A 1 63  ? 97.264  25.288  37.417  1.00 138.23 ? 138  HIS A ND1 1 
ATOM   447   C CD2 . HIS A 1 63  ? 97.784  26.866  38.835  1.00 126.94 ? 138  HIS A CD2 1 
ATOM   448   C CE1 . HIS A 1 63  ? 98.493  25.047  37.836  1.00 137.69 ? 138  HIS A CE1 1 
ATOM   449   N NE2 . HIS A 1 63  ? 98.833  25.989  38.697  1.00 136.46 ? 138  HIS A NE2 1 
ATOM   450   N N   . MET A 1 64  ? 92.288  26.646  38.086  1.00 116.36 ? 139  MET A N   1 
ATOM   451   C CA  . MET A 1 64  ? 91.015  27.057  37.511  1.00 116.08 ? 139  MET A CA  1 
ATOM   452   C C   . MET A 1 64  ? 90.071  27.570  38.593  1.00 101.38 ? 139  MET A C   1 
ATOM   453   O O   . MET A 1 64  ? 89.946  26.968  39.665  1.00 103.08 ? 139  MET A O   1 
ATOM   454   C CB  . MET A 1 64  ? 90.409  25.877  36.747  1.00 105.94 ? 139  MET A CB  1 
ATOM   455   C CG  . MET A 1 64  ? 90.347  26.078  35.239  1.00 119.42 ? 139  MET A CG  1 
ATOM   456   S SD  . MET A 1 64  ? 89.432  24.773  34.388  1.00 116.84 ? 139  MET A SD  1 
ATOM   457   C CE  . MET A 1 64  ? 87.733  25.311  34.430  1.00 110.07 ? 139  MET A CE  1 
ATOM   458   N N   . GLN A 1 65  ? 89.423  28.699  38.317  1.00 92.40  ? 140  GLN A N   1 
ATOM   459   C CA  . GLN A 1 65  ? 88.526  29.304  39.288  1.00 97.73  ? 140  GLN A CA  1 
ATOM   460   C C   . GLN A 1 65  ? 87.279  28.439  39.427  1.00 96.97  ? 140  GLN A C   1 
ATOM   461   O O   . GLN A 1 65  ? 86.889  27.729  38.497  1.00 95.84  ? 140  GLN A O   1 
ATOM   462   C CB  . GLN A 1 65  ? 88.143  30.718  38.852  1.00 97.19  ? 140  GLN A CB  1 
ATOM   463   C CG  . GLN A 1 65  ? 87.599  31.589  39.972  1.00 97.72  ? 140  GLN A CG  1 
ATOM   464   C CD  . GLN A 1 65  ? 88.704  32.075  40.886  1.00 93.58  ? 140  GLN A CD  1 
ATOM   465   O OE1 . GLN A 1 65  ? 88.655  31.894  42.100  1.00 116.88 ? 140  GLN A OE1 1 
ATOM   466   N NE2 . GLN A 1 65  ? 89.713  32.703  40.299  1.00 78.05  ? 140  GLN A NE2 1 
ATOM   467   N N   . ASN A 1 66  ? 86.649  28.504  40.604  1.00 91.22  ? 141  ASN A N   1 
ATOM   468   C CA  . ASN A 1 66  ? 85.491  27.653  40.867  1.00 83.38  ? 141  ASN A CA  1 
ATOM   469   C C   . ASN A 1 66  ? 84.377  27.893  39.855  1.00 86.60  ? 141  ASN A C   1 
ATOM   470   O O   . ASN A 1 66  ? 83.698  26.949  39.439  1.00 83.95  ? 141  ASN A O   1 
ATOM   471   C CB  . ASN A 1 66  ? 84.975  27.873  42.286  1.00 84.31  ? 141  ASN A CB  1 
ATOM   472   C CG  . ASN A 1 66  ? 85.752  27.086  43.321  1.00 82.04  ? 141  ASN A CG  1 
ATOM   473   O OD1 . ASN A 1 66  ? 85.923  25.874  43.193  1.00 76.11  ? 141  ASN A OD1 1 
ATOM   474   N ND2 . ASN A 1 66  ? 86.205  27.766  44.368  1.00 96.26  ? 141  ASN A ND2 1 
ATOM   475   N N   . SER A 1 67  ? 84.170  29.147  39.447  1.00 85.49  ? 142  SER A N   1 
ATOM   476   C CA  . SER A 1 67  ? 83.141  29.441  38.453  1.00 77.75  ? 142  SER A CA  1 
ATOM   477   C C   . SER A 1 67  ? 83.426  28.717  37.142  1.00 89.58  ? 142  SER A C   1 
ATOM   478   O O   . SER A 1 67  ? 82.532  28.095  36.547  1.00 85.79  ? 142  SER A O   1 
ATOM   479   C CB  . SER A 1 67  ? 83.052  30.949  38.225  1.00 73.65  ? 142  SER A CB  1 
ATOM   480   O OG  . SER A 1 67  ? 84.252  31.437  37.651  1.00 73.43  ? 142  SER A OG  1 
ATOM   481   N N   . GLU A 1 68  ? 84.676  28.789  36.677  1.00 97.00  ? 143  GLU A N   1 
ATOM   482   C CA  . GLU A 1 68  ? 85.053  28.095  35.451  1.00 101.48 ? 143  GLU A CA  1 
ATOM   483   C C   . GLU A 1 68  ? 84.885  26.590  35.602  1.00 96.91  ? 143  GLU A C   1 
ATOM   484   O O   . GLU A 1 68  ? 84.434  25.910  34.671  1.00 97.69  ? 143  GLU A O   1 
ATOM   485   C CB  . GLU A 1 68  ? 86.500  28.407  35.077  1.00 100.01 ? 143  GLU A CB  1 
ATOM   486   C CG  . GLU A 1 68  ? 86.958  29.832  35.233  1.00 113.95 ? 143  GLU A CG  1 
ATOM   487   C CD  . GLU A 1 68  ? 88.410  29.972  34.839  1.00 122.52 ? 143  GLU A CD  1 
ATOM   488   O OE1 . GLU A 1 68  ? 88.737  29.610  33.689  1.00 117.92 ? 143  GLU A OE1 1 
ATOM   489   O OE2 . GLU A 1 68  ? 89.223  30.420  35.676  1.00 124.78 ? 143  GLU A OE2 1 
ATOM   490   N N   . ILE A 1 69  ? 85.290  26.046  36.754  1.00 84.55  ? 144  ILE A N   1 
ATOM   491   C CA  . ILE A 1 69  ? 85.138  24.615  36.995  1.00 80.32  ? 144  ILE A CA  1 
ATOM   492   C C   . ILE A 1 69  ? 83.673  24.224  36.904  1.00 84.90  ? 144  ILE A C   1 
ATOM   493   O O   . ILE A 1 69  ? 83.324  23.203  36.303  1.00 85.01  ? 144  ILE A O   1 
ATOM   494   C CB  . ILE A 1 69  ? 85.741  24.227  38.358  1.00 72.80  ? 144  ILE A CB  1 
ATOM   495   C CG1 . ILE A 1 69  ? 87.235  24.549  38.398  1.00 80.76  ? 144  ILE A CG1 1 
ATOM   496   C CG2 . ILE A 1 69  ? 85.508  22.753  38.643  1.00 58.47  ? 144  ILE A CG2 1 
ATOM   497   C CD1 . ILE A 1 69  ? 87.855  24.345  39.759  1.00 78.21  ? 144  ILE A CD1 1 
ATOM   498   N N   . ILE A 1 70  ? 82.793  25.043  37.480  1.00 86.46  ? 145  ILE A N   1 
ATOM   499   C CA  . ILE A 1 70  ? 81.361  24.766  37.438  1.00 85.42  ? 145  ILE A CA  1 
ATOM   500   C C   . ILE A 1 70  ? 80.857  24.781  36.005  1.00 97.04  ? 145  ILE A C   1 
ATOM   501   O O   . ILE A 1 70  ? 80.044  23.939  35.609  1.00 96.73  ? 145  ILE A O   1 
ATOM   502   C CB  . ILE A 1 70  ? 80.602  25.776  38.316  1.00 83.51  ? 145  ILE A CB  1 
ATOM   503   C CG1 . ILE A 1 70  ? 80.955  25.558  39.784  1.00 74.11  ? 145  ILE A CG1 1 
ATOM   504   C CG2 . ILE A 1 70  ? 79.099  25.662  38.100  1.00 94.32  ? 145  ILE A CG2 1 
ATOM   505   C CD1 . ILE A 1 70  ? 80.598  26.716  40.650  1.00 71.62  ? 145  ILE A CD1 1 
ATOM   506   N N   . ARG A 1 71  ? 81.323  25.743  35.206  1.00 92.48  ? 146  ARG A N   1 
ATOM   507   C CA  . ARG A 1 71  ? 80.900  25.797  33.808  1.00 90.36  ? 146  ARG A CA  1 
ATOM   508   C C   . ARG A 1 71  ? 81.346  24.550  33.052  1.00 94.09  ? 146  ARG A C   1 
ATOM   509   O O   . ARG A 1 71  ? 80.561  23.946  32.304  1.00 101.51 ? 146  ARG A O   1 
ATOM   510   C CB  . ARG A 1 71  ? 81.443  27.067  33.154  1.00 85.08  ? 146  ARG A CB  1 
ATOM   511   C CG  . ARG A 1 71  ? 80.867  28.339  33.769  1.00 91.89  ? 146  ARG A CG  1 
ATOM   512   C CD  . ARG A 1 71  ? 81.296  29.602  33.041  1.00 83.03  ? 146  ARG A CD  1 
ATOM   513   N NE  . ARG A 1 71  ? 82.731  29.663  32.791  1.00 96.61  ? 146  ARG A NE  1 
ATOM   514   C CZ  . ARG A 1 71  ? 83.551  30.541  33.353  1.00 101.14 ? 146  ARG A CZ  1 
ATOM   515   N NH1 . ARG A 1 71  ? 83.122  31.409  34.255  1.00 92.52  ? 146  ARG A NH1 1 
ATOM   516   N NH2 . ARG A 1 71  ? 84.832  30.551  32.997  1.00 112.88 ? 146  ARG A NH2 1 
ATOM   517   N N   . LYS A 1 72  ? 82.601  24.141  33.258  1.00 88.11  ? 147  LYS A N   1 
ATOM   518   C CA  . LYS A 1 72  ? 83.105  22.907  32.662  1.00 92.19  ? 147  LYS A CA  1 
ATOM   519   C C   . LYS A 1 72  ? 82.277  21.704  33.097  1.00 94.82  ? 147  LYS A C   1 
ATOM   520   O O   . LYS A 1 72  ? 82.045  20.782  32.307  1.00 103.57 ? 147  LYS A O   1 
ATOM   521   C CB  . LYS A 1 72  ? 84.572  22.710  33.045  1.00 88.88  ? 147  LYS A CB  1 
ATOM   522   C CG  . LYS A 1 72  ? 85.248  21.494  32.429  1.00 110.43 ? 147  LYS A CG  1 
ATOM   523   C CD  . LYS A 1 72  ? 85.229  21.536  30.909  1.00 113.17 ? 147  LYS A CD  1 
ATOM   524   C CE  . LYS A 1 72  ? 85.873  20.290  30.322  1.00 101.71 ? 147  LYS A CE  1 
ATOM   525   N NZ  . LYS A 1 72  ? 85.626  20.153  28.861  1.00 114.02 ? 147  LYS A NZ  1 
ATOM   526   N N   . MET A 1 73  ? 81.831  21.689  34.355  1.00 88.04  ? 148  MET A N   1 
ATOM   527   C CA  . MET A 1 73  ? 81.039  20.560  34.834  1.00 91.88  ? 148  MET A CA  1 
ATOM   528   C C   . MET A 1 73  ? 79.649  20.558  34.212  1.00 97.22  ? 148  MET A C   1 
ATOM   529   O O   . MET A 1 73  ? 79.095  19.491  33.921  1.00 96.69  ? 148  MET A O   1 
ATOM   530   C CB  . MET A 1 73  ? 80.942  20.583  36.361  1.00 88.65  ? 148  MET A CB  1 
ATOM   531   C CG  . MET A 1 73  ? 82.280  20.534  37.093  1.00 94.91  ? 148  MET A CG  1 
ATOM   532   S SD  . MET A 1 73  ? 83.554  19.537  36.298  1.00 86.53  ? 148  MET A SD  1 
ATOM   533   C CE  . MET A 1 73  ? 82.788  17.927  36.364  1.00 73.07  ? 148  MET A CE  1 
ATOM   534   N N   . THR A 1 74  ? 79.063  21.742  34.021  1.00 93.62  ? 149  THR A N   1 
ATOM   535   C CA  . THR A 1 74  ? 77.793  21.828  33.307  1.00 93.37  ? 149  THR A CA  1 
ATOM   536   C C   . THR A 1 74  ? 77.929  21.264  31.901  1.00 103.11 ? 149  THR A C   1 
ATOM   537   O O   . THR A 1 74  ? 77.095  20.466  31.458  1.00 107.19 ? 149  THR A O   1 
ATOM   538   C CB  . THR A 1 74  ? 77.287  23.272  33.250  1.00 88.94  ? 149  THR A CB  1 
ATOM   539   O OG1 . THR A 1 74  ? 78.145  24.053  32.407  1.00 113.43 ? 149  THR A OG1 1 
ATOM   540   C CG2 . THR A 1 74  ? 77.215  23.886  34.636  1.00 78.74  ? 149  THR A CG2 1 
ATOM   541   N N   . GLU A 1 75  ? 78.983  21.660  31.182  1.00 100.70 ? 150  GLU A N   1 
ATOM   542   C CA  . GLU A 1 75  ? 79.162  21.109  29.843  1.00 101.13 ? 150  GLU A CA  1 
ATOM   543   C C   . GLU A 1 75  ? 79.633  19.658  29.868  1.00 96.84  ? 150  GLU A C   1 
ATOM   544   O O   . GLU A 1 75  ? 79.484  18.957  28.863  1.00 108.78 ? 150  GLU A O   1 
ATOM   545   C CB  . GLU A 1 75  ? 80.133  21.967  29.031  1.00 92.52  ? 150  GLU A CB  1 
ATOM   546   C CG  . GLU A 1 75  ? 81.584  21.822  29.420  1.00 98.33  ? 150  GLU A CG  1 
ATOM   547   C CD  . GLU A 1 75  ? 82.475  22.762  28.642  1.00 105.15 ? 150  GLU A CD  1 
ATOM   548   O OE1 . GLU A 1 75  ? 82.299  23.991  28.779  1.00 99.12  ? 150  GLU A OE1 1 
ATOM   549   O OE2 . GLU A 1 75  ? 83.345  22.274  27.888  1.00 96.41  ? 150  GLU A OE2 1 
ATOM   550   N N   . GLU A 1 76  ? 80.188  19.189  30.988  1.00 90.96  ? 151  GLU A N   1 
ATOM   551   C CA  . GLU A 1 76  ? 80.615  17.803  31.142  1.00 98.72  ? 151  GLU A CA  1 
ATOM   552   C C   . GLU A 1 76  ? 79.611  16.968  31.929  1.00 96.94  ? 151  GLU A C   1 
ATOM   553   O O   . GLU A 1 76  ? 79.967  15.905  32.446  1.00 98.27  ? 151  GLU A O   1 
ATOM   554   C CB  . GLU A 1 76  ? 81.982  17.739  31.825  1.00 111.78 ? 151  GLU A CB  1 
ATOM   555   C CG  . GLU A 1 76  ? 83.162  18.034  30.919  1.00 110.40 ? 151  GLU A CG  1 
ATOM   556   C CD  . GLU A 1 76  ? 83.639  16.814  30.155  1.00 133.65 ? 151  GLU A CD  1 
ATOM   557   O OE1 . GLU A 1 76  ? 84.150  16.982  29.029  1.00 144.44 ? 151  GLU A OE1 1 
ATOM   558   O OE2 . GLU A 1 76  ? 83.515  15.690  30.687  1.00 137.01 ? 151  GLU A OE2 1 
ATOM   559   N N   . PHE A 1 77  ? 78.364  17.432  32.031  1.00 94.90  ? 152  PHE A N   1 
ATOM   560   C CA  . PHE A 1 77  ? 77.385  16.766  32.883  1.00 98.96  ? 152  PHE A CA  1 
ATOM   561   C C   . PHE A 1 77  ? 77.004  15.390  32.348  1.00 102.14 ? 152  PHE A C   1 
ATOM   562   O O   . PHE A 1 77  ? 76.770  14.467  33.138  1.00 106.01 ? 152  PHE A O   1 
ATOM   563   C CB  . PHE A 1 77  ? 76.148  17.653  33.028  1.00 100.82 ? 152  PHE A CB  1 
ATOM   564   C CG  . PHE A 1 77  ? 75.506  17.591  34.383  1.00 90.00  ? 152  PHE A CG  1 
ATOM   565   C CD1 . PHE A 1 77  ? 74.807  16.465  34.783  1.00 86.17  ? 152  PHE A CD1 1 
ATOM   566   C CD2 . PHE A 1 77  ? 75.611  18.657  35.263  1.00 86.49  ? 152  PHE A CD2 1 
ATOM   567   C CE1 . PHE A 1 77  ? 74.208  16.408  36.028  1.00 79.99  ? 152  PHE A CE1 1 
ATOM   568   C CE2 . PHE A 1 77  ? 75.021  18.604  36.513  1.00 87.65  ? 152  PHE A CE2 1 
ATOM   569   C CZ  . PHE A 1 77  ? 74.320  17.477  36.896  1.00 79.99  ? 152  PHE A CZ  1 
ATOM   570   N N   . ASP A 1 78  ? 76.945  15.233  31.023  1.00 101.95 ? 153  ASP A N   1 
ATOM   571   C CA  . ASP A 1 78  ? 76.482  13.993  30.390  1.00 104.60 ? 153  ASP A CA  1 
ATOM   572   C C   . ASP A 1 78  ? 75.129  13.560  30.944  1.00 108.81 ? 153  ASP A C   1 
ATOM   573   O O   . ASP A 1 78  ? 74.849  12.372  31.113  1.00 114.72 ? 153  ASP A O   1 
ATOM   574   C CB  . ASP A 1 78  ? 77.515  12.875  30.533  1.00 97.18  ? 153  ASP A CB  1 
ATOM   575   C CG  . ASP A 1 78  ? 78.796  13.170  29.786  1.00 117.59 ? 153  ASP A CG  1 
ATOM   576   O OD1 . ASP A 1 78  ? 79.368  14.262  29.986  1.00 130.87 ? 153  ASP A OD1 1 
ATOM   577   O OD2 . ASP A 1 78  ? 79.230  12.308  28.994  1.00 124.53 ? 153  ASP A OD2 1 
ATOM   578   N N   . GLU A 1 79  ? 74.282  14.542  31.232  1.00 98.43  ? 154  GLU A N   1 
ATOM   579   C CA  . GLU A 1 79  ? 72.956  14.260  31.756  1.00 92.82  ? 154  GLU A CA  1 
ATOM   580   C C   . GLU A 1 79  ? 72.107  13.575  30.695  1.00 97.00  ? 154  GLU A C   1 
ATOM   581   O O   . GLU A 1 79  ? 72.189  13.895  29.505  1.00 113.12 ? 154  GLU A O   1 
ATOM   582   C CB  . GLU A 1 79  ? 72.286  15.556  32.217  1.00 104.11 ? 154  GLU A CB  1 
ATOM   583   C CG  . GLU A 1 79  ? 71.958  16.540  31.094  1.00 98.11  ? 154  GLU A CG  1 
ATOM   584   C CD  . GLU A 1 79  ? 73.184  17.291  30.603  1.00 103.56 ? 154  GLU A CD  1 
ATOM   585   O OE1 . GLU A 1 79  ? 74.096  16.644  30.048  1.00 111.38 ? 154  GLU A OE1 1 
ATOM   586   O OE2 . GLU A 1 79  ? 73.251  18.522  30.784  1.00 103.73 ? 154  GLU A OE2 1 
ATOM   587   N N   . ASP A 1 80  ? 71.308  12.605  31.128  1.00 99.83  ? 155  ASP A N   1 
ATOM   588   C CA  . ASP A 1 80  ? 70.320  11.987  30.259  1.00 112.82 ? 155  ASP A CA  1 
ATOM   589   C C   . ASP A 1 80  ? 68.911  12.491  30.530  1.00 108.25 ? 155  ASP A C   1 
ATOM   590   O O   . ASP A 1 80  ? 68.005  12.208  29.739  1.00 115.04 ? 155  ASP A O   1 
ATOM   591   C CB  . ASP A 1 80  ? 70.357  10.460  30.405  1.00 114.46 ? 155  ASP A CB  1 
ATOM   592   C CG  . ASP A 1 80  ? 69.884  9.992   31.766  1.00 128.56 ? 155  ASP A CG  1 
ATOM   593   O OD1 . ASP A 1 80  ? 70.449  10.443  32.785  1.00 140.44 ? 155  ASP A OD1 1 
ATOM   594   O OD2 . ASP A 1 80  ? 68.943  9.174   31.815  1.00 128.16 ? 155  ASP A OD2 1 
ATOM   595   N N   . SER A 1 81  ? 68.710  13.232  31.615  1.00 105.66 ? 156  SER A N   1 
ATOM   596   C CA  . SER A 1 81  ? 67.401  13.761  31.973  1.00 103.27 ? 156  SER A CA  1 
ATOM   597   C C   . SER A 1 81  ? 67.607  14.936  32.920  1.00 101.19 ? 156  SER A C   1 
ATOM   598   O O   . SER A 1 81  ? 68.737  15.354  33.187  1.00 109.04 ? 156  SER A O   1 
ATOM   599   C CB  . SER A 1 81  ? 66.523  12.680  32.609  1.00 100.54 ? 156  SER A CB  1 
ATOM   600   O OG  . SER A 1 81  ? 67.085  12.217  33.825  1.00 88.79  ? 156  SER A OG  1 
ATOM   601   N N   . GLY A 1 82  ? 66.498  15.468  33.431  1.00 89.70  ? 157  GLY A N   1 
ATOM   602   C CA  . GLY A 1 82  ? 66.562  16.535  34.408  1.00 90.21  ? 157  GLY A CA  1 
ATOM   603   C C   . GLY A 1 82  ? 66.650  16.076  35.843  1.00 83.62  ? 157  GLY A C   1 
ATOM   604   O O   . GLY A 1 82  ? 66.881  16.898  36.734  1.00 78.91  ? 157  GLY A O   1 
ATOM   605   N N   . ASP A 1 83  ? 66.470  14.780  36.087  1.00 85.64  ? 158  ASP A N   1 
ATOM   606   C CA  . ASP A 1 83  ? 66.556  14.248  37.439  1.00 92.75  ? 158  ASP A CA  1 
ATOM   607   C C   . ASP A 1 83  ? 67.983  14.337  37.965  1.00 87.63  ? 158  ASP A C   1 
ATOM   608   O O   . ASP A 1 83  ? 68.947  14.050  37.248  1.00 97.03  ? 158  ASP A O   1 
ATOM   609   C CB  . ASP A 1 83  ? 66.093  12.791  37.466  1.00 88.14  ? 158  ASP A CB  1 
ATOM   610   C CG  . ASP A 1 83  ? 64.708  12.604  36.882  1.00 98.08  ? 158  ASP A CG  1 
ATOM   611   O OD1 . ASP A 1 83  ? 63.749  13.198  37.418  1.00 94.39  ? 158  ASP A OD1 1 
ATOM   612   O OD2 . ASP A 1 83  ? 64.580  11.857  35.889  1.00 107.20 ? 158  ASP A OD2 1 
ATOM   613   N N   . TYR A 1 84  ? 68.117  14.746  39.219  1.00 79.58  ? 159  TYR A N   1 
ATOM   614   C CA  . TYR A 1 84  ? 69.372  14.662  39.947  1.00 77.95  ? 159  TYR A CA  1 
ATOM   615   C C   . TYR A 1 84  ? 69.104  13.984  41.283  1.00 80.36  ? 159  TYR A C   1 
ATOM   616   O O   . TYR A 1 84  ? 67.964  13.974  41.760  1.00 78.37  ? 159  TYR A O   1 
ATOM   617   C CB  . TYR A 1 84  ? 70.024  16.042  40.148  1.00 68.83  ? 159  TYR A CB  1 
ATOM   618   C CG  . TYR A 1 84  ? 69.151  17.148  40.698  1.00 67.79  ? 159  TYR A CG  1 
ATOM   619   C CD1 . TYR A 1 84  ? 68.286  17.855  39.875  1.00 67.79  ? 159  TYR A CD1 1 
ATOM   620   C CD2 . TYR A 1 84  ? 69.237  17.524  42.033  1.00 78.59  ? 159  TYR A CD2 1 
ATOM   621   C CE1 . TYR A 1 84  ? 67.503  18.881  40.375  1.00 71.01  ? 159  TYR A CE1 1 
ATOM   622   C CE2 . TYR A 1 84  ? 68.461  18.549  42.540  1.00 65.31  ? 159  TYR A CE2 1 
ATOM   623   C CZ  . TYR A 1 84  ? 67.597  19.225  41.706  1.00 63.52  ? 159  TYR A CZ  1 
ATOM   624   O OH  . TYR A 1 84  ? 66.822  20.244  42.208  1.00 74.62  ? 159  TYR A OH  1 
ATOM   625   N N   . PRO A 1 85  ? 70.137  13.384  41.902  1.00 71.82  ? 160  PRO A N   1 
ATOM   626   C CA  . PRO A 1 85  ? 69.906  12.484  43.049  1.00 69.07  ? 160  PRO A CA  1 
ATOM   627   C C   . PRO A 1 85  ? 68.960  13.007  44.118  1.00 75.88  ? 160  PRO A C   1 
ATOM   628   O O   . PRO A 1 85  ? 68.143  12.235  44.638  1.00 74.87  ? 160  PRO A O   1 
ATOM   629   C CB  . PRO A 1 85  ? 71.320  12.294  43.604  1.00 65.85  ? 160  PRO A CB  1 
ATOM   630   C CG  . PRO A 1 85  ? 72.175  12.333  42.397  1.00 78.55  ? 160  PRO A CG  1 
ATOM   631   C CD  . PRO A 1 85  ? 71.550  13.358  41.477  1.00 70.66  ? 160  PRO A CD  1 
ATOM   632   N N   . LEU A 1 86  ? 69.043  14.293  44.463  1.00 77.88  ? 161  LEU A N   1 
ATOM   633   C CA  . LEU A 1 86  ? 68.172  14.826  45.504  1.00 78.15  ? 161  LEU A CA  1 
ATOM   634   C C   . LEU A 1 86  ? 66.713  14.844  45.071  1.00 79.59  ? 161  LEU A C   1 
ATOM   635   O O   . LEU A 1 86  ? 65.823  14.644  45.904  1.00 84.08  ? 161  LEU A O   1 
ATOM   636   C CB  . LEU A 1 86  ? 68.633  16.228  45.905  1.00 71.63  ? 161  LEU A CB  1 
ATOM   637   C CG  . LEU A 1 86  ? 69.928  16.265  46.716  1.00 72.16  ? 161  LEU A CG  1 
ATOM   638   C CD1 . LEU A 1 86  ? 70.070  17.594  47.436  1.00 78.11  ? 161  LEU A CD1 1 
ATOM   639   C CD2 . LEU A 1 86  ? 69.981  15.102  47.702  1.00 63.34  ? 161  LEU A CD2 1 
ATOM   640   N N   . THR A 1 87  ? 66.449  15.073  43.783  1.00 77.20  ? 162  THR A N   1 
ATOM   641   C CA  . THR A 1 87  ? 65.081  15.041  43.280  1.00 77.89  ? 162  THR A CA  1 
ATOM   642   C C   . THR A 1 87  ? 64.636  13.629  42.922  1.00 77.63  ? 162  THR A C   1 
ATOM   643   O O   . THR A 1 87  ? 63.437  13.330  42.976  1.00 60.25  ? 162  THR A O   1 
ATOM   644   C CB  . THR A 1 87  ? 64.941  15.947  42.053  1.00 77.28  ? 162  THR A CB  1 
ATOM   645   O OG1 . THR A 1 87  ? 66.088  15.791  41.207  1.00 85.70  ? 162  THR A OG1 1 
ATOM   646   C CG2 . THR A 1 87  ? 64.811  17.404  42.471  1.00 74.82  ? 162  THR A CG2 1 
ATOM   647   N N   . MET A 1 88  ? 65.578  12.763  42.548  1.00 83.50  ? 163  MET A N   1 
ATOM   648   C CA  . MET A 1 88  ? 65.248  11.394  42.173  1.00 73.19  ? 163  MET A CA  1 
ATOM   649   C C   . MET A 1 88  ? 64.562  10.670  43.323  1.00 81.54  ? 163  MET A C   1 
ATOM   650   O O   . MET A 1 88  ? 65.060  10.659  44.452  1.00 95.43  ? 163  MET A O   1 
ATOM   651   C CB  . MET A 1 88  ? 66.515  10.642  41.762  1.00 68.62  ? 163  MET A CB  1 
ATOM   652   C CG  . MET A 1 88  ? 66.966  10.909  40.340  1.00 79.68  ? 163  MET A CG  1 
ATOM   653   S SD  . MET A 1 88  ? 68.347  9.866   39.832  1.00 113.28 ? 163  MET A SD  1 
ATOM   654   C CE  . MET A 1 88  ? 69.303  11.015  38.844  1.00 92.87  ? 163  MET A CE  1 
ATOM   655   N N   . ALA A 1 89  ? 63.416  10.068  43.033  1.00 80.76  ? 164  ALA A N   1 
ATOM   656   C CA  . ALA A 1 89  ? 62.681  9.312   44.031  1.00 80.54  ? 164  ALA A CA  1 
ATOM   657   C C   . ALA A 1 89  ? 63.194  7.876   44.096  1.00 96.19  ? 164  ALA A C   1 
ATOM   658   O O   . ALA A 1 89  ? 63.931  7.407   43.226  1.00 98.18  ? 164  ALA A O   1 
ATOM   659   C CB  . ALA A 1 89  ? 61.183  9.332   43.726  1.00 78.58  ? 164  ALA A CB  1 
ATOM   660   N N   . GLY A 1 90  ? 62.793  7.174   45.153  1.00 91.91  ? 165  GLY A N   1 
ATOM   661   C CA  . GLY A 1 90  ? 63.203  5.806   45.353  1.00 99.99  ? 165  GLY A CA  1 
ATOM   662   C C   . GLY A 1 90  ? 63.933  5.616   46.666  1.00 113.89 ? 165  GLY A C   1 
ATOM   663   O O   . GLY A 1 90  ? 64.627  6.514   47.153  1.00 113.91 ? 165  GLY A O   1 
ATOM   664   N N   . PRO A 1 91  ? 63.784  4.432   47.268  1.00 118.02 ? 166  PRO A N   1 
ATOM   665   C CA  . PRO A 1 91  ? 64.411  4.196   48.582  1.00 109.85 ? 166  PRO A CA  1 
ATOM   666   C C   . PRO A 1 91  ? 65.918  4.381   48.583  1.00 105.52 ? 166  PRO A C   1 
ATOM   667   O O   . PRO A 1 91  ? 66.469  4.926   49.551  1.00 107.88 ? 166  PRO A O   1 
ATOM   668   C CB  . PRO A 1 91  ? 64.015  2.746   48.893  1.00 107.07 ? 166  PRO A CB  1 
ATOM   669   C CG  . PRO A 1 91  ? 62.756  2.525   48.121  1.00 95.82  ? 166  PRO A CG  1 
ATOM   670   C CD  . PRO A 1 91  ? 62.923  3.312   46.853  1.00 100.67 ? 166  PRO A CD  1 
ATOM   671   N N   . GLN A 1 92  ? 66.602  3.941   47.523  1.00 107.72 ? 167  GLN A N   1 
ATOM   672   C CA  . GLN A 1 92  ? 68.050  4.111   47.462  1.00 112.36 ? 167  GLN A CA  1 
ATOM   673   C C   . GLN A 1 92  ? 68.423  5.587   47.514  1.00 111.93 ? 167  GLN A C   1 
ATOM   674   O O   . GLN A 1 92  ? 69.389  5.971   48.182  1.00 118.18 ? 167  GLN A O   1 
ATOM   675   C CB  . GLN A 1 92  ? 68.621  3.450   46.201  1.00 112.66 ? 167  GLN A CB  1 
ATOM   676   C CG  . GLN A 1 92  ? 68.172  4.047   44.863  1.00 121.27 ? 167  GLN A CG  1 
ATOM   677   C CD  . GLN A 1 92  ? 66.702  3.829   44.552  1.00 121.50 ? 167  GLN A CD  1 
ATOM   678   O OE1 . GLN A 1 92  ? 66.003  3.098   45.253  1.00 120.24 ? 167  GLN A OE1 1 
ATOM   679   N NE2 . GLN A 1 92  ? 66.223  4.479   43.497  1.00 125.98 ? 167  GLN A NE2 1 
ATOM   680   N N   . TRP A 1 93  ? 67.631  6.440   46.861  1.00 101.79 ? 168  TRP A N   1 
ATOM   681   C CA  . TRP A 1 93  ? 67.948  7.861   46.824  1.00 96.28  ? 168  TRP A CA  1 
ATOM   682   C C   . TRP A 1 93  ? 67.558  8.570   48.117  1.00 93.72  ? 168  TRP A C   1 
ATOM   683   O O   . TRP A 1 93  ? 68.204  9.552   48.496  1.00 98.62  ? 168  TRP A O   1 
ATOM   684   C CB  . TRP A 1 93  ? 67.273  8.508   45.615  1.00 87.49  ? 168  TRP A CB  1 
ATOM   685   C CG  . TRP A 1 93  ? 67.926  8.129   44.315  1.00 84.44  ? 168  TRP A CG  1 
ATOM   686   C CD1 . TRP A 1 93  ? 67.318  7.578   43.225  1.00 87.48  ? 168  TRP A CD1 1 
ATOM   687   C CD2 . TRP A 1 93  ? 69.312  8.281   43.967  1.00 88.64  ? 168  TRP A CD2 1 
ATOM   688   N NE1 . TRP A 1 93  ? 68.237  7.371   42.225  1.00 90.19  ? 168  TRP A NE1 1 
ATOM   689   C CE2 . TRP A 1 93  ? 69.467  7.795   42.654  1.00 89.81  ? 168  TRP A CE2 1 
ATOM   690   C CE3 . TRP A 1 93  ? 70.433  8.780   44.638  1.00 87.84  ? 168  TRP A CE3 1 
ATOM   691   C CZ2 . TRP A 1 93  ? 70.699  7.793   42.000  1.00 98.39  ? 168  TRP A CZ2 1 
ATOM   692   C CZ3 . TRP A 1 93  ? 71.655  8.776   43.988  1.00 81.15  ? 168  TRP A CZ3 1 
ATOM   693   C CH2 . TRP A 1 93  ? 71.778  8.287   42.682  1.00 91.38  ? 168  TRP A CH2 1 
ATOM   694   N N   . LYS A 1 94  ? 66.532  8.082   48.818  1.00 85.58  ? 169  LYS A N   1 
ATOM   695   C CA  . LYS A 1 94  ? 66.233  8.615   50.144  1.00 87.51  ? 169  LYS A CA  1 
ATOM   696   C C   . LYS A 1 94  ? 67.363  8.290   51.116  1.00 97.60  ? 169  LYS A C   1 
ATOM   697   O O   . LYS A 1 94  ? 67.840  9.163   51.863  1.00 105.72 ? 169  LYS A O   1 
ATOM   698   C CB  . LYS A 1 94  ? 64.907  8.045   50.650  1.00 78.41  ? 169  LYS A CB  1 
ATOM   699   C CG  . LYS A 1 94  ? 63.693  8.313   49.755  1.00 113.54 ? 169  LYS A CG  1 
ATOM   700   C CD  . LYS A 1 94  ? 63.656  9.733   49.208  1.00 118.16 ? 169  LYS A CD  1 
ATOM   701   C CE  . LYS A 1 94  ? 63.955  9.765   47.714  1.00 114.32 ? 169  LYS A CE  1 
ATOM   702   N NZ  . LYS A 1 94  ? 64.155  11.155  47.223  1.00 104.13 ? 169  LYS A NZ  1 
ATOM   703   N N   . LYS A 1 95  ? 67.798  7.025   51.117  1.00 93.31  ? 170  LYS A N   1 
ATOM   704   C CA  . LYS A 1 95  ? 68.969  6.629   51.891  1.00 88.60  ? 170  LYS A CA  1 
ATOM   705   C C   . LYS A 1 95  ? 70.189  7.456   51.504  1.00 96.02  ? 170  LYS A C   1 
ATOM   706   O O   . LYS A 1 95  ? 71.006  7.807   52.362  1.00 105.10 ? 170  LYS A O   1 
ATOM   707   C CB  . LYS A 1 95  ? 69.241  5.136   51.691  1.00 83.91  ? 170  LYS A CB  1 
ATOM   708   C CG  . LYS A 1 95  ? 70.660  4.694   52.020  1.00 112.26 ? 170  LYS A CG  1 
ATOM   709   C CD  . LYS A 1 95  ? 70.968  3.346   51.386  1.00 123.52 ? 170  LYS A CD  1 
ATOM   710   C CE  . LYS A 1 95  ? 72.418  2.937   51.593  1.00 140.07 ? 170  LYS A CE  1 
ATOM   711   N NZ  . LYS A 1 95  ? 72.770  2.845   53.036  1.00 145.92 ? 170  LYS A NZ  1 
ATOM   712   N N   . PHE A 1 96  ? 70.322  7.791   50.216  1.00 81.12  ? 171  PHE A N   1 
ATOM   713   C CA  . PHE A 1 96  ? 71.446  8.612   49.776  1.00 82.69  ? 171  PHE A CA  1 
ATOM   714   C C   . PHE A 1 96  ? 71.368  10.023  50.341  1.00 85.93  ? 171  PHE A C   1 
ATOM   715   O O   . PHE A 1 96  ? 72.384  10.590  50.745  1.00 86.33  ? 171  PHE A O   1 
ATOM   716   C CB  . PHE A 1 96  ? 71.511  8.680   48.253  1.00 73.43  ? 171  PHE A CB  1 
ATOM   717   C CG  . PHE A 1 96  ? 72.361  9.812   47.755  1.00 63.85  ? 171  PHE A CG  1 
ATOM   718   C CD1 . PHE A 1 96  ? 73.741  9.729   47.810  1.00 75.36  ? 171  PHE A CD1 1 
ATOM   719   C CD2 . PHE A 1 96  ? 71.783  10.972  47.266  1.00 60.24  ? 171  PHE A CD2 1 
ATOM   720   C CE1 . PHE A 1 96  ? 74.531  10.773  47.372  1.00 72.32  ? 171  PHE A CE1 1 
ATOM   721   C CE2 . PHE A 1 96  ? 72.568  12.020  46.827  1.00 69.42  ? 171  PHE A CE2 1 
ATOM   722   C CZ  . PHE A 1 96  ? 73.944  11.920  46.877  1.00 74.74  ? 171  PHE A CZ  1 
ATOM   723   N N   . LYS A 1 97  ? 70.182  10.633  50.308  1.00 84.49  ? 172  LYS A N   1 
ATOM   724   C CA  . LYS A 1 97  ? 70.014  11.960  50.894  1.00 77.57  ? 172  LYS A CA  1 
ATOM   725   C C   . LYS A 1 97  ? 70.433  11.952  52.359  1.00 80.47  ? 172  LYS A C   1 
ATOM   726   O O   . LYS A 1 97  ? 71.226  12.798  52.812  1.00 84.81  ? 172  LYS A O   1 
ATOM   727   C CB  . LYS A 1 97  ? 68.557  12.406  50.753  1.00 68.06  ? 172  LYS A CB  1 
ATOM   728   C CG  . LYS A 1 97  ? 68.174  13.578  51.643  1.00 69.39  ? 172  LYS A CG  1 
ATOM   729   C CD  . LYS A 1 97  ? 67.203  14.531  50.955  1.00 87.53  ? 172  LYS A CD  1 
ATOM   730   C CE  . LYS A 1 97  ? 66.133  13.781  50.172  1.00 100.20 ? 172  LYS A CE  1 
ATOM   731   N NZ  . LYS A 1 97  ? 65.082  14.695  49.643  1.00 118.66 ? 172  LYS A NZ  1 
ATOM   732   N N   . SER A 1 98  ? 69.912  10.977  53.110  1.00 77.51  ? 173  SER A N   1 
ATOM   733   C CA  . SER A 1 98  ? 70.245  10.874  54.527  1.00 75.89  ? 173  SER A CA  1 
ATOM   734   C C   . SER A 1 98  ? 71.745  10.683  54.727  1.00 75.71  ? 173  SER A C   1 
ATOM   735   O O   . SER A 1 98  ? 72.360  11.340  55.578  1.00 76.64  ? 173  SER A O   1 
ATOM   736   C CB  . SER A 1 98  ? 69.460  9.728   55.166  1.00 88.38  ? 173  SER A CB  1 
ATOM   737   O OG  . SER A 1 98  ? 68.080  9.821   54.853  1.00 104.45 ? 173  SER A OG  1 
ATOM   738   N N   . SER A 1 99  ? 72.356  9.801   53.932  1.00 74.69  ? 174  SER A N   1 
ATOM   739   C CA  . SER A 1 99  ? 73.778  9.510   54.082  1.00 70.55  ? 174  SER A CA  1 
ATOM   740   C C   . SER A 1 99  ? 74.636  10.705  53.692  1.00 72.94  ? 174  SER A C   1 
ATOM   741   O O   . SER A 1 99  ? 75.701  10.923  54.271  1.00 81.91  ? 174  SER A O   1 
ATOM   742   C CB  . SER A 1 99  ? 74.146  8.292   53.238  1.00 72.83  ? 174  SER A CB  1 
ATOM   743   O OG  . SER A 1 99  ? 73.252  7.219   53.477  1.00 77.05  ? 174  SER A OG  1 
ATOM   744   N N   . PHE A 1 100 ? 74.186  11.487  52.713  1.00 64.67  ? 175  PHE A N   1 
ATOM   745   C CA  . PHE A 1 100 ? 74.892  12.694  52.300  1.00 62.06  ? 175  PHE A CA  1 
ATOM   746   C C   . PHE A 1 100 ? 74.945  13.704  53.441  1.00 66.55  ? 175  PHE A C   1 
ATOM   747   O O   . PHE A 1 100 ? 76.023  14.207  53.810  1.00 68.47  ? 175  PHE A O   1 
ATOM   748   C CB  . PHE A 1 100 ? 74.175  13.263  51.072  1.00 61.59  ? 175  PHE A CB  1 
ATOM   749   C CG  . PHE A 1 100 ? 74.716  14.567  50.572  1.00 58.24  ? 175  PHE A CG  1 
ATOM   750   C CD1 . PHE A 1 100 ? 76.007  14.665  50.085  1.00 66.99  ? 175  PHE A CD1 1 
ATOM   751   C CD2 . PHE A 1 100 ? 73.909  15.692  50.553  1.00 55.74  ? 175  PHE A CD2 1 
ATOM   752   C CE1 . PHE A 1 100 ? 76.490  15.868  49.606  1.00 67.22  ? 175  PHE A CE1 1 
ATOM   753   C CE2 . PHE A 1 100 ? 74.384  16.895  50.079  1.00 52.12  ? 175  PHE A CE2 1 
ATOM   754   C CZ  . PHE A 1 100 ? 75.676  16.985  49.605  1.00 56.34  ? 175  PHE A CZ  1 
ATOM   755   N N   . CYS A 1 101 ? 73.782  13.994  54.031  1.00 62.21  ? 176  CYS A N   1 
ATOM   756   C CA  . CYS A 1 101 ? 73.753  14.921  55.160  1.00 58.55  ? 176  CYS A CA  1 
ATOM   757   C C   . CYS A 1 101 ? 74.578  14.393  56.334  1.00 69.30  ? 176  CYS A C   1 
ATOM   758   O O   . CYS A 1 101 ? 75.328  15.151  56.973  1.00 69.57  ? 176  CYS A O   1 
ATOM   759   C CB  . CYS A 1 101 ? 72.307  15.187  55.577  1.00 57.36  ? 176  CYS A CB  1 
ATOM   760   S SG  . CYS A 1 101 ? 71.267  15.800  54.226  1.00 74.14  ? 176  CYS A SG  1 
ATOM   761   N N   . GLU A 1 102 ? 74.463  13.092  56.625  1.00 65.33  ? 177  GLU A N   1 
ATOM   762   C CA  . GLU A 1 102 ? 75.256  12.508  57.703  1.00 66.77  ? 177  GLU A CA  1 
ATOM   763   C C   . GLU A 1 102 ? 76.745  12.613  57.417  1.00 63.94  ? 177  GLU A C   1 
ATOM   764   O O   . GLU A 1 102 ? 77.543  12.841  58.331  1.00 66.48  ? 177  GLU A O   1 
ATOM   765   C CB  . GLU A 1 102 ? 74.883  11.045  57.924  1.00 69.01  ? 177  GLU A CB  1 
ATOM   766   C CG  . GLU A 1 102 ? 75.637  10.431  59.096  1.00 74.79  ? 177  GLU A CG  1 
ATOM   767   C CD  . GLU A 1 102 ? 75.378  8.951   59.271  1.00 93.63  ? 177  GLU A CD  1 
ATOM   768   O OE1 . GLU A 1 102 ? 74.643  8.371   58.446  1.00 90.83  ? 177  GLU A OE1 1 
ATOM   769   O OE2 . GLU A 1 102 ? 75.922  8.369   60.234  1.00 99.48  ? 177  GLU A OE2 1 
ATOM   770   N N   . PHE A 1 103 ? 77.143  12.406  56.162  1.00 64.10  ? 178  PHE A N   1 
ATOM   771   C CA  . PHE A 1 103 ? 78.543  12.546  55.791  1.00 65.49  ? 178  PHE A CA  1 
ATOM   772   C C   . PHE A 1 103 ? 79.047  13.938  56.116  1.00 62.50  ? 178  PHE A C   1 
ATOM   773   O O   . PHE A 1 103 ? 80.133  14.097  56.681  1.00 64.54  ? 178  PHE A O   1 
ATOM   774   C CB  . PHE A 1 103 ? 78.730  12.248  54.304  1.00 67.87  ? 178  PHE A CB  1 
ATOM   775   C CG  . PHE A 1 103 ? 80.159  12.323  53.854  1.00 67.15  ? 178  PHE A CG  1 
ATOM   776   C CD1 . PHE A 1 103 ? 81.042  11.290  54.118  1.00 66.43  ? 178  PHE A CD1 1 
ATOM   777   C CD2 . PHE A 1 103 ? 80.626  13.446  53.191  1.00 65.98  ? 178  PHE A CD2 1 
ATOM   778   C CE1 . PHE A 1 103 ? 82.360  11.369  53.707  1.00 70.63  ? 178  PHE A CE1 1 
ATOM   779   C CE2 . PHE A 1 103 ? 81.940  13.532  52.781  1.00 65.02  ? 178  PHE A CE2 1 
ATOM   780   C CZ  . PHE A 1 103 ? 82.809  12.493  53.039  1.00 68.58  ? 178  PHE A CZ  1 
ATOM   781   N N   . ILE A 1 104 ? 78.269  14.962  55.762  1.00 61.04  ? 179  ILE A N   1 
ATOM   782   C CA  . ILE A 1 104 ? 78.685  16.329  56.077  1.00 48.67  ? 179  ILE A CA  1 
ATOM   783   C C   . ILE A 1 104 ? 78.860  16.498  57.584  1.00 47.03  ? 179  ILE A C   1 
ATOM   784   O O   . ILE A 1 104 ? 79.903  16.977  58.065  1.00 56.54  ? 179  ILE A O   1 
ATOM   785   C CB  . ILE A 1 104 ? 77.681  17.343  55.505  1.00 50.39  ? 179  ILE A CB  1 
ATOM   786   C CG1 . ILE A 1 104 ? 77.533  17.134  53.999  1.00 53.20  ? 179  ILE A CG1 1 
ATOM   787   C CG2 . ILE A 1 104 ? 78.137  18.762  55.801  1.00 50.54  ? 179  ILE A CG2 1 
ATOM   788   C CD1 . ILE A 1 104 ? 76.222  17.620  53.439  1.00 56.39  ? 179  ILE A CD1 1 
ATOM   789   N N   . GLY A 1 105 ? 77.844  16.091  58.351  1.00 49.43  ? 180  GLY A N   1 
ATOM   790   C CA  . GLY A 1 105 ? 77.910  16.260  59.797  1.00 54.64  ? 180  GLY A CA  1 
ATOM   791   C C   . GLY A 1 105 ? 79.095  15.547  60.422  1.00 54.32  ? 180  GLY A C   1 
ATOM   792   O O   . GLY A 1 105 ? 79.826  16.117  61.239  1.00 57.76  ? 180  GLY A O   1 
ATOM   793   N N   . VAL A 1 106 ? 79.313  14.290  60.031  1.00 61.89  ? 181  VAL A N   1 
ATOM   794   C CA  . VAL A 1 106 ? 80.393  13.492  60.603  1.00 62.45  ? 181  VAL A CA  1 
ATOM   795   C C   . VAL A 1 106 ? 81.750  14.025  60.164  1.00 59.89  ? 181  VAL A C   1 
ATOM   796   O O   . VAL A 1 106 ? 82.713  14.008  60.939  1.00 61.49  ? 181  VAL A O   1 
ATOM   797   C CB  . VAL A 1 106 ? 80.218  12.009  60.224  1.00 50.96  ? 181  VAL A CB  1 
ATOM   798   C CG1 . VAL A 1 106 ? 81.389  11.185  60.731  1.00 62.40  ? 181  VAL A CG1 1 
ATOM   799   C CG2 . VAL A 1 106 ? 78.915  11.471  60.788  1.00 63.98  ? 181  VAL A CG2 1 
ATOM   800   N N   . LEU A 1 107 ? 81.859  14.495  58.919  1.00 54.42  ? 182  LEU A N   1 
ATOM   801   C CA  . LEU A 1 107 ? 83.112  15.081  58.462  1.00 54.66  ? 182  LEU A CA  1 
ATOM   802   C C   . LEU A 1 107 ? 83.489  16.275  59.321  1.00 59.88  ? 182  LEU A C   1 
ATOM   803   O O   . LEU A 1 107 ? 84.650  16.428  59.717  1.00 62.19  ? 182  LEU A O   1 
ATOM   804   C CB  . LEU A 1 107 ? 83.006  15.488  56.993  1.00 47.54  ? 182  LEU A CB  1 
ATOM   805   C CG  . LEU A 1 107 ? 84.313  15.986  56.371  1.00 57.82  ? 182  LEU A CG  1 
ATOM   806   C CD1 . LEU A 1 107 ? 85.352  14.873  56.320  1.00 60.19  ? 182  LEU A CD1 1 
ATOM   807   C CD2 . LEU A 1 107 ? 84.066  16.555  54.984  1.00 59.95  ? 182  LEU A CD2 1 
ATOM   808   N N   . VAL A 1 108 ? 82.514  17.130  59.635  1.00 57.64  ? 183  VAL A N   1 
ATOM   809   C CA  . VAL A 1 108 ? 82.808  18.248  60.531  1.00 48.56  ? 183  VAL A CA  1 
ATOM   810   C C   . VAL A 1 108 ? 83.191  17.731  61.912  1.00 58.04  ? 183  VAL A C   1 
ATOM   811   O O   . VAL A 1 108 ? 84.159  18.197  62.525  1.00 61.81  ? 183  VAL A O   1 
ATOM   812   C CB  . VAL A 1 108 ? 81.618  19.216  60.605  1.00 56.94  ? 183  VAL A CB  1 
ATOM   813   C CG1 . VAL A 1 108 ? 81.950  20.386  61.521  1.00 57.59  ? 183  VAL A CG1 1 
ATOM   814   C CG2 . VAL A 1 108 ? 81.267  19.702  59.223  1.00 57.62  ? 183  VAL A CG2 1 
ATOM   815   N N   . ARG A 1 109 ? 82.444  16.744  62.413  1.00 61.38  ? 184  ARG A N   1 
ATOM   816   C CA  . ARG A 1 109 ? 82.664  16.252  63.771  1.00 64.82  ? 184  ARG A CA  1 
ATOM   817   C C   . ARG A 1 109 ? 84.068  15.687  63.946  1.00 66.55  ? 184  ARG A C   1 
ATOM   818   O O   . ARG A 1 109 ? 84.736  15.956  64.951  1.00 67.45  ? 184  ARG A O   1 
ATOM   819   C CB  . ARG A 1 109 ? 81.616  15.194  64.101  1.00 63.69  ? 184  ARG A CB  1 
ATOM   820   C CG  . ARG A 1 109 ? 81.695  14.621  65.498  1.00 69.51  ? 184  ARG A CG  1 
ATOM   821   C CD  . ARG A 1 109 ? 80.389  13.928  65.816  1.00 88.12  ? 184  ARG A CD  1 
ATOM   822   N NE  . ARG A 1 109 ? 79.268  14.845  65.647  1.00 88.91  ? 184  ARG A NE  1 
ATOM   823   C CZ  . ARG A 1 109 ? 78.320  14.710  64.729  1.00 93.53  ? 184  ARG A CZ  1 
ATOM   824   N NH1 . ARG A 1 109 ? 78.327  13.704  63.869  1.00 93.59  ? 184  ARG A NH1 1 
ATOM   825   N NH2 . ARG A 1 109 ? 77.343  15.610  64.668  1.00 105.50 ? 184  ARG A NH2 1 
ATOM   826   N N   . GLN A 1 110 ? 84.533  14.902  62.976  1.00 72.70  ? 185  GLN A N   1 
ATOM   827   C CA  . GLN A 1 110 ? 85.815  14.225  63.096  1.00 70.86  ? 185  GLN A CA  1 
ATOM   828   C C   . GLN A 1 110 ? 86.996  15.169  62.922  1.00 68.42  ? 185  GLN A C   1 
ATOM   829   O O   . GLN A 1 110 ? 88.098  14.855  63.383  1.00 78.52  ? 185  GLN A O   1 
ATOM   830   C CB  . GLN A 1 110 ? 85.900  13.095  62.070  1.00 70.60  ? 185  GLN A CB  1 
ATOM   831   C CG  . GLN A 1 110 ? 84.873  12.006  62.280  1.00 79.84  ? 185  GLN A CG  1 
ATOM   832   C CD  . GLN A 1 110 ? 84.881  11.471  63.692  1.00 87.85  ? 185  GLN A CD  1 
ATOM   833   O OE1 . GLN A 1 110 ? 83.896  11.600  64.416  1.00 98.91  ? 185  GLN A OE1 1 
ATOM   834   N NE2 . GLN A 1 110 ? 85.991  10.862  64.093  1.00 83.14  ? 185  GLN A NE2 1 
ATOM   835   N N   . CYS A 1 111 ? 86.794  16.309  62.267  1.00 59.51  ? 186  CYS A N   1 
ATOM   836   C CA  . CYS A 1 111 ? 87.841  17.300  62.077  1.00 68.14  ? 186  CYS A CA  1 
ATOM   837   C C   . CYS A 1 111 ? 87.724  18.474  63.039  1.00 69.05  ? 186  CYS A C   1 
ATOM   838   O O   . CYS A 1 111 ? 88.528  19.406  62.952  1.00 70.51  ? 186  CYS A O   1 
ATOM   839   C CB  . CYS A 1 111 ? 87.824  17.819  60.635  1.00 54.01  ? 186  CYS A CB  1 
ATOM   840   S SG  . CYS A 1 111 ? 87.725  16.549  59.352  1.00 74.61  ? 186  CYS A SG  1 
ATOM   841   N N   . GLN A 1 112 ? 86.764  18.441  63.966  1.00 63.96  ? 187  GLN A N   1 
ATOM   842   C CA  . GLN A 1 112 ? 86.382  19.637  64.710  1.00 68.06  ? 187  GLN A CA  1 
ATOM   843   C C   . GLN A 1 112 ? 87.432  20.098  65.714  1.00 65.73  ? 187  GLN A C   1 
ATOM   844   O O   . GLN A 1 112 ? 87.257  21.170  66.305  1.00 62.49  ? 187  GLN A O   1 
ATOM   845   C CB  . GLN A 1 112 ? 85.060  19.410  65.443  1.00 67.58  ? 187  GLN A CB  1 
ATOM   846   C CG  . GLN A 1 112 ? 85.179  18.582  66.709  1.00 50.00  ? 187  GLN A CG  1 
ATOM   847   C CD  . GLN A 1 112 ? 83.830  18.258  67.316  1.00 64.48  ? 187  GLN A CD  1 
ATOM   848   O OE1 . GLN A 1 112 ? 83.068  19.156  67.678  1.00 65.40  ? 187  GLN A OE1 1 
ATOM   849   N NE2 . GLN A 1 112 ? 83.527  16.971  67.436  1.00 78.19  ? 187  GLN A NE2 1 
ATOM   850   N N   . TYR A 1 113 ? 88.506  19.340  65.930  1.00 67.06  ? 188  TYR A N   1 
ATOM   851   C CA  . TYR A 1 113 ? 89.524  19.729  66.895  1.00 66.90  ? 188  TYR A CA  1 
ATOM   852   C C   . TYR A 1 113 ? 90.876  20.023  66.261  1.00 63.90  ? 188  TYR A C   1 
ATOM   853   O O   . TYR A 1 113 ? 91.800  20.428  66.975  1.00 50.06  ? 188  TYR A O   1 
ATOM   854   C CB  . TYR A 1 113 ? 89.692  18.641  67.964  1.00 59.39  ? 188  TYR A CB  1 
ATOM   855   C CG  . TYR A 1 113 ? 88.435  18.332  68.739  1.00 63.02  ? 188  TYR A CG  1 
ATOM   856   C CD1 . TYR A 1 113 ? 87.833  19.294  69.541  1.00 60.30  ? 188  TYR A CD1 1 
ATOM   857   C CD2 . TYR A 1 113 ? 87.851  17.075  68.670  1.00 73.66  ? 188  TYR A CD2 1 
ATOM   858   C CE1 . TYR A 1 113 ? 86.681  19.008  70.251  1.00 79.72  ? 188  TYR A CE1 1 
ATOM   859   C CE2 . TYR A 1 113 ? 86.703  16.781  69.375  1.00 73.98  ? 188  TYR A CE2 1 
ATOM   860   C CZ  . TYR A 1 113 ? 86.120  17.750  70.164  1.00 76.88  ? 188  TYR A CZ  1 
ATOM   861   O OH  . TYR A 1 113 ? 84.975  17.458  70.868  1.00 62.46  ? 188  TYR A OH  1 
ATOM   862   N N   . SER A 1 114 ? 91.020  19.839  64.949  1.00 72.35  ? 189  SER A N   1 
ATOM   863   C CA  . SER A 1 114 ? 92.303  20.062  64.294  1.00 67.52  ? 189  SER A CA  1 
ATOM   864   C C   . SER A 1 114 ? 92.131  20.473  62.836  1.00 60.47  ? 189  SER A C   1 
ATOM   865   O O   . SER A 1 114 ? 92.383  21.628  62.480  1.00 61.40  ? 189  SER A O   1 
ATOM   866   C CB  . SER A 1 114 ? 93.171  18.803  64.386  1.00 75.98  ? 189  SER A CB  1 
ATOM   867   O OG  . SER A 1 114 ? 94.502  19.068  63.980  1.00 91.86  ? 189  SER A OG  1 
ATOM   868   N N   . ILE A 1 115 ? 91.701  19.531  61.991  1.00 63.82  ? 190  ILE A N   1 
ATOM   869   C CA  . ILE A 1 115 ? 91.612  19.783  60.554  1.00 64.22  ? 190  ILE A CA  1 
ATOM   870   C C   . ILE A 1 115 ? 90.673  20.941  60.250  1.00 72.38  ? 190  ILE A C   1 
ATOM   871   O O   . ILE A 1 115 ? 90.850  21.646  59.251  1.00 70.49  ? 190  ILE A O   1 
ATOM   872   C CB  . ILE A 1 115 ? 91.172  18.505  59.812  1.00 63.95  ? 190  ILE A CB  1 
ATOM   873   C CG1 . ILE A 1 115 ? 91.893  17.277  60.370  1.00 69.86  ? 190  ILE A CG1 1 
ATOM   874   C CG2 . ILE A 1 115 ? 91.406  18.646  58.317  1.00 60.59  ? 190  ILE A CG2 1 
ATOM   875   C CD1 . ILE A 1 115 ? 91.586  15.999  59.621  1.00 75.50  ? 190  ILE A CD1 1 
ATOM   876   N N   . ILE A 1 116 ? 89.655  21.151  61.088  1.00 79.15  ? 191  ILE A N   1 
ATOM   877   C CA  . ILE A 1 116 ? 88.751  22.278  60.875  1.00 70.47  ? 191  ILE A CA  1 
ATOM   878   C C   . ILE A 1 116 ? 89.502  23.594  61.010  1.00 72.17  ? 191  ILE A C   1 
ATOM   879   O O   . ILE A 1 116 ? 89.176  24.576  60.332  1.00 76.59  ? 191  ILE A O   1 
ATOM   880   C CB  . ILE A 1 116 ? 87.551  22.197  61.842  1.00 66.04  ? 191  ILE A CB  1 
ATOM   881   C CG1 . ILE A 1 116 ? 86.403  23.087  61.367  1.00 60.63  ? 191  ILE A CG1 1 
ATOM   882   C CG2 . ILE A 1 116 ? 87.956  22.589  63.251  1.00 76.12  ? 191  ILE A CG2 1 
ATOM   883   C CD1 . ILE A 1 116 ? 85.145  22.917  62.182  1.00 70.45  ? 191  ILE A CD1 1 
ATOM   884   N N   . TYR A 1 117 ? 90.527  23.632  61.858  1.00 66.97  ? 192  TYR A N   1 
ATOM   885   C CA  . TYR A 1 117 ? 91.339  24.823  62.054  1.00 68.71  ? 192  TYR A CA  1 
ATOM   886   C C   . TYR A 1 117 ? 92.575  24.844  61.171  1.00 85.89  ? 192  TYR A C   1 
ATOM   887   O O   . TYR A 1 117 ? 93.347  25.806  61.237  1.00 90.24  ? 192  TYR A O   1 
ATOM   888   C CB  . TYR A 1 117 ? 91.749  24.947  63.525  1.00 59.61  ? 192  TYR A CB  1 
ATOM   889   C CG  . TYR A 1 117 ? 90.596  24.803  64.493  1.00 56.67  ? 192  TYR A CG  1 
ATOM   890   C CD1 . TYR A 1 117 ? 89.555  25.723  64.507  1.00 53.79  ? 192  TYR A CD1 1 
ATOM   891   C CD2 . TYR A 1 117 ? 90.541  23.740  65.385  1.00 64.26  ? 192  TYR A CD2 1 
ATOM   892   C CE1 . TYR A 1 117 ? 88.495  25.594  65.388  1.00 58.91  ? 192  TYR A CE1 1 
ATOM   893   C CE2 . TYR A 1 117 ? 89.485  23.601  66.268  1.00 80.11  ? 192  TYR A CE2 1 
ATOM   894   C CZ  . TYR A 1 117 ? 88.464  24.530  66.265  1.00 72.27  ? 192  TYR A CZ  1 
ATOM   895   O OH  . TYR A 1 117 ? 87.410  24.396  67.141  1.00 64.84  ? 192  TYR A OH  1 
ATOM   896   N N   . ASP A 1 118 ? 92.787  23.816  60.345  1.00 90.16  ? 193  ASP A N   1 
ATOM   897   C CA  . ASP A 1 118 ? 93.904  23.865  59.410  1.00 80.42  ? 193  ASP A CA  1 
ATOM   898   C C   . ASP A 1 118 ? 93.732  24.973  58.381  1.00 89.98  ? 193  ASP A C   1 
ATOM   899   O O   . ASP A 1 118 ? 94.721  25.403  57.779  1.00 71.58  ? 193  ASP A O   1 
ATOM   900   C CB  . ASP A 1 118 ? 94.091  22.507  58.719  1.00 72.75  ? 193  ASP A CB  1 
ATOM   901   C CG  . ASP A 1 118 ? 93.177  22.309  57.510  1.00 85.33  ? 193  ASP A CG  1 
ATOM   902   O OD1 . ASP A 1 118 ? 92.125  22.974  57.402  1.00 107.24 ? 193  ASP A OD1 1 
ATOM   903   O OD2 . ASP A 1 118 ? 93.527  21.476  56.647  1.00 66.62  ? 193  ASP A OD2 1 
ATOM   904   N N   . GLU A 1 119 ? 92.495  25.433  58.170  1.00 129.80 ? 194  GLU A N   1 
ATOM   905   C CA  . GLU A 1 119 ? 92.199  26.531  57.253  1.00 134.29 ? 194  GLU A CA  1 
ATOM   906   C C   . GLU A 1 119 ? 92.676  26.217  55.836  1.00 103.54 ? 194  GLU A C   1 
ATOM   907   O O   . GLU A 1 119 ? 93.228  27.070  55.137  1.00 81.26  ? 194  GLU A O   1 
ATOM   908   C CB  . GLU A 1 119 ? 92.789  27.844  57.775  1.00 147.98 ? 194  GLU A CB  1 
ATOM   909   C CG  . GLU A 1 119 ? 92.252  28.205  59.153  1.00 167.85 ? 194  GLU A CG  1 
ATOM   910   C CD  . GLU A 1 119 ? 93.314  28.754  60.083  1.00 200.69 ? 194  GLU A CD  1 
ATOM   911   O OE1 . GLU A 1 119 ? 94.381  29.179  59.591  1.00 207.06 ? 194  GLU A OE1 1 
ATOM   912   O OE2 . GLU A 1 119 ? 93.085  28.748  61.311  1.00 204.64 ? 194  GLU A OE2 1 
ATOM   913   N N   . TYR A 1 120 ? 92.456  24.972  55.416  1.00 87.15  ? 195  TYR A N   1 
ATOM   914   C CA  . TYR A 1 120 ? 92.677  24.555  54.039  1.00 79.36  ? 195  TYR A CA  1 
ATOM   915   C C   . TYR A 1 120 ? 91.450  23.808  53.530  1.00 89.21  ? 195  TYR A C   1 
ATOM   916   O O   . TYR A 1 120 ? 90.821  24.236  52.557  1.00 87.72  ? 195  TYR A O   1 
ATOM   917   C CB  . TYR A 1 120 ? 93.931  23.681  53.928  1.00 88.72  ? 195  TYR A CB  1 
ATOM   918   C CG  . TYR A 1 120 ? 94.318  23.313  52.508  1.00 92.32  ? 195  TYR A CG  1 
ATOM   919   C CD1 . TYR A 1 120 ? 94.158  24.218  51.467  1.00 91.70  ? 195  TYR A CD1 1 
ATOM   920   C CD2 . TYR A 1 120 ? 94.845  22.060  52.210  1.00 89.82  ? 195  TYR A CD2 1 
ATOM   921   C CE1 . TYR A 1 120 ? 94.511  23.885  50.168  1.00 93.98  ? 195  TYR A CE1 1 
ATOM   922   C CE2 . TYR A 1 120 ? 95.203  21.718  50.915  1.00 90.79  ? 195  TYR A CE2 1 
ATOM   923   C CZ  . TYR A 1 120 ? 95.032  22.635  49.897  1.00 95.53  ? 195  TYR A CZ  1 
ATOM   924   O OH  . TYR A 1 120 ? 95.382  22.304  48.606  1.00 80.07  ? 195  TYR A OH  1 
ATOM   925   N N   . MET A 1 121 ? 91.086  22.704  54.194  1.00 82.82  ? 196  MET A N   1 
ATOM   926   C CA  . MET A 1 121 ? 89.948  21.912  53.731  1.00 81.46  ? 196  MET A CA  1 
ATOM   927   C C   . MET A 1 121 ? 88.627  22.627  53.982  1.00 73.44  ? 196  MET A C   1 
ATOM   928   O O   . MET A 1 121 ? 87.724  22.581  53.140  1.00 78.39  ? 196  MET A O   1 
ATOM   929   C CB  . MET A 1 121 ? 89.948  20.529  54.390  1.00 75.57  ? 196  MET A CB  1 
ATOM   930   C CG  . MET A 1 121 ? 89.601  20.508  55.866  1.00 72.37  ? 196  MET A CG  1 
ATOM   931   S SD  . MET A 1 121 ? 87.849  20.197  56.165  1.00 76.78  ? 196  MET A SD  1 
ATOM   932   C CE  . MET A 1 121 ? 87.678  18.512  55.605  1.00 64.03  ? 196  MET A CE  1 
ATOM   933   N N   . MET A 1 122 ? 88.491  23.294  55.130  1.00 71.84  ? 197  MET A N   1 
ATOM   934   C CA  . MET A 1 122 ? 87.253  24.012  55.417  1.00 74.69  ? 197  MET A CA  1 
ATOM   935   C C   . MET A 1 122 ? 87.043  25.161  54.438  1.00 73.15  ? 197  MET A C   1 
ATOM   936   O O   . MET A 1 122 ? 85.940  25.351  53.908  1.00 68.90  ? 197  MET A O   1 
ATOM   937   C CB  . MET A 1 122 ? 87.266  24.534  56.855  1.00 78.95  ? 197  MET A CB  1 
ATOM   938   C CG  . MET A 1 122 ? 85.885  24.850  57.437  1.00 69.74  ? 197  MET A CG  1 
ATOM   939   S SD  . MET A 1 122 ? 84.527  23.665  57.265  1.00 81.70  ? 197  MET A SD  1 
ATOM   940   C CE  . MET A 1 122 ? 85.334  22.086  57.526  1.00 63.61  ? 197  MET A CE  1 
ATOM   941   N N   . ASP A 1 123 ? 88.095  25.947  54.199  1.00 70.89  ? 198  ASP A N   1 
ATOM   942   C CA  . ASP A 1 123 ? 87.999  27.066  53.268  1.00 75.29  ? 198  ASP A CA  1 
ATOM   943   C C   . ASP A 1 123 ? 87.717  26.572  51.854  1.00 75.66  ? 198  ASP A C   1 
ATOM   944   O O   . ASP A 1 123 ? 86.885  27.146  51.141  1.00 77.91  ? 198  ASP A O   1 
ATOM   945   C CB  . ASP A 1 123 ? 89.287  27.894  53.326  1.00 75.02  ? 198  ASP A CB  1 
ATOM   946   C CG  . ASP A 1 123 ? 89.557  28.675  52.045  1.00 82.91  ? 198  ASP A CG  1 
ATOM   947   O OD1 . ASP A 1 123 ? 88.638  29.352  51.537  1.00 65.56  ? 198  ASP A OD1 1 
ATOM   948   O OD2 . ASP A 1 123 ? 90.704  28.617  51.551  1.00 88.21  ? 198  ASP A OD2 1 
ATOM   949   N N   . THR A 1 124 ? 88.385  25.492  51.442  1.00 68.11  ? 199  THR A N   1 
ATOM   950   C CA  . THR A 1 124 ? 88.135  24.909  50.127  1.00 80.21  ? 199  THR A CA  1 
ATOM   951   C C   . THR A 1 124 ? 86.686  24.453  49.996  1.00 74.62  ? 199  THR A C   1 
ATOM   952   O O   . THR A 1 124 ? 86.029  24.702  48.975  1.00 69.24  ? 199  THR A O   1 
ATOM   953   C CB  . THR A 1 124 ? 89.090  23.735  49.888  1.00 79.21  ? 199  THR A CB  1 
ATOM   954   O OG1 . THR A 1 124 ? 90.442  24.200  49.929  1.00 78.11  ? 199  THR A OG1 1 
ATOM   955   C CG2 . THR A 1 124 ? 88.825  23.095  48.532  1.00 66.07  ? 199  THR A CG2 1 
ATOM   956   N N   . VAL A 1 125 ? 86.171  23.775  51.024  1.00 73.19  ? 200  VAL A N   1 
ATOM   957   C CA  . VAL A 1 125 ? 84.812  23.246  50.967  1.00 65.85  ? 200  VAL A CA  1 
ATOM   958   C C   . VAL A 1 125 ? 83.803  24.382  50.890  1.00 67.19  ? 200  VAL A C   1 
ATOM   959   O O   . VAL A 1 125 ? 82.876  24.355  50.071  1.00 59.26  ? 200  VAL A O   1 
ATOM   960   C CB  . VAL A 1 125 ? 84.539  22.329  52.172  1.00 48.20  ? 200  VAL A CB  1 
ATOM   961   C CG1 . VAL A 1 125 ? 83.043  22.154  52.369  1.00 47.95  ? 200  VAL A CG1 1 
ATOM   962   C CG2 . VAL A 1 125 ? 85.196  20.982  51.957  1.00 34.15  ? 200  VAL A CG2 1 
ATOM   963   N N   . ILE A 1 126 ? 83.964  25.397  51.743  1.00 63.79  ? 201  ILE A N   1 
ATOM   964   C CA  . ILE A 1 126 ? 83.014  26.506  51.737  1.00 72.51  ? 201  ILE A CA  1 
ATOM   965   C C   . ILE A 1 126 ? 83.079  27.256  50.410  1.00 73.81  ? 201  ILE A C   1 
ATOM   966   O O   . ILE A 1 126 ? 82.048  27.671  49.868  1.00 69.42  ? 201  ILE A O   1 
ATOM   967   C CB  . ILE A 1 126 ? 83.256  27.437  52.940  1.00 50.20  ? 201  ILE A CB  1 
ATOM   968   C CG1 . ILE A 1 126 ? 82.667  26.824  54.212  1.00 49.35  ? 201  ILE A CG1 1 
ATOM   969   C CG2 . ILE A 1 126 ? 82.636  28.801  52.697  1.00 49.13  ? 201  ILE A CG2 1 
ATOM   970   C CD1 . ILE A 1 126 ? 83.460  27.127  55.459  1.00 65.08  ? 201  ILE A CD1 1 
ATOM   971   N N   . SER A 1 127 ? 84.281  27.406  49.846  1.00 68.38  ? 202  SER A N   1 
ATOM   972   C CA  . SER A 1 127 ? 84.413  28.089  48.563  1.00 66.15  ? 202  SER A CA  1 
ATOM   973   C C   . SER A 1 127 ? 83.690  27.328  47.458  1.00 78.77  ? 202  SER A C   1 
ATOM   974   O O   . SER A 1 127 ? 82.914  27.912  46.687  1.00 88.69  ? 202  SER A O   1 
ATOM   975   C CB  . SER A 1 127 ? 85.892  28.266  48.221  1.00 72.27  ? 202  SER A CB  1 
ATOM   976   O OG  . SER A 1 127 ? 86.602  28.829  49.310  1.00 76.79  ? 202  SER A OG  1 
ATOM   977   N N   . LEU A 1 128 ? 83.937  26.018  47.367  1.00 74.34  ? 203  LEU A N   1 
ATOM   978   C CA  . LEU A 1 128 ? 83.274  25.209  46.350  1.00 72.91  ? 203  LEU A CA  1 
ATOM   979   C C   . LEU A 1 128 ? 81.760  25.233  46.524  1.00 80.36  ? 203  LEU A C   1 
ATOM   980   O O   . LEU A 1 128 ? 81.015  25.368  45.543  1.00 76.55  ? 203  LEU A O   1 
ATOM   981   C CB  . LEU A 1 128 ? 83.797  23.775  46.404  1.00 61.56  ? 203  LEU A CB  1 
ATOM   982   C CG  . LEU A 1 128 ? 83.002  22.735  45.614  1.00 63.90  ? 203  LEU A CG  1 
ATOM   983   C CD1 . LEU A 1 128 ? 83.427  22.749  44.157  1.00 55.22  ? 203  LEU A CD1 1 
ATOM   984   C CD2 . LEU A 1 128 ? 83.156  21.347  46.215  1.00 56.25  ? 203  LEU A CD2 1 
ATOM   985   N N   . LEU A 1 129 ? 81.286  25.123  47.768  1.00 79.34  ? 204  LEU A N   1 
ATOM   986   C CA  . LEU A 1 129 ? 79.848  25.088  48.006  1.00 62.12  ? 204  LEU A CA  1 
ATOM   987   C C   . LEU A 1 129 ? 79.196  26.423  47.676  1.00 59.92  ? 204  LEU A C   1 
ATOM   988   O O   . LEU A 1 129 ? 78.089  26.456  47.130  1.00 78.69  ? 204  LEU A O   1 
ATOM   989   C CB  . LEU A 1 129 ? 79.557  24.692  49.454  1.00 49.05  ? 204  LEU A CB  1 
ATOM   990   C CG  . LEU A 1 129 ? 79.793  23.227  49.829  1.00 62.69  ? 204  LEU A CG  1 
ATOM   991   C CD1 . LEU A 1 129 ? 79.201  22.926  51.197  1.00 66.17  ? 204  LEU A CD1 1 
ATOM   992   C CD2 . LEU A 1 129 ? 79.220  22.292  48.775  1.00 65.72  ? 204  LEU A CD2 1 
ATOM   993   N N   . THR A 1 130 ? 79.862  27.537  47.991  1.00 62.32  ? 205  THR A N   1 
ATOM   994   C CA  . THR A 1 130 ? 79.328  28.845  47.625  1.00 67.50  ? 205  THR A CA  1 
ATOM   995   C C   . THR A 1 130 ? 79.239  28.988  46.111  1.00 80.79  ? 205  THR A C   1 
ATOM   996   O O   . THR A 1 130 ? 78.195  29.387  45.567  1.00 81.49  ? 205  THR A O   1 
ATOM   997   C CB  . THR A 1 130 ? 80.204  29.951  48.216  1.00 63.15  ? 205  THR A CB  1 
ATOM   998   O OG1 . THR A 1 130 ? 80.357  29.746  49.627  1.00 66.21  ? 205  THR A OG1 1 
ATOM   999   C CG2 . THR A 1 130 ? 79.583  31.315  47.969  1.00 71.63  ? 205  THR A CG2 1 
ATOM   1000  N N   . GLY A 1 131 ? 80.331  28.663  45.413  1.00 80.93  ? 206  GLY A N   1 
ATOM   1001  C CA  . GLY A 1 131 ? 80.305  28.712  43.961  1.00 77.84  ? 206  GLY A CA  1 
ATOM   1002  C C   . GLY A 1 131 ? 79.175  27.893  43.371  1.00 72.60  ? 206  GLY A C   1 
ATOM   1003  O O   . GLY A 1 131 ? 78.472  28.347  42.465  1.00 77.71  ? 206  GLY A O   1 
ATOM   1004  N N   . LEU A 1 132 ? 78.978  26.675  43.883  1.00 69.30  ? 207  LEU A N   1 
ATOM   1005  C CA  . LEU A 1 132 ? 77.900  25.832  43.374  1.00 70.69  ? 207  LEU A CA  1 
ATOM   1006  C C   . LEU A 1 132 ? 76.528  26.378  43.755  1.00 72.87  ? 207  LEU A C   1 
ATOM   1007  O O   . LEU A 1 132 ? 75.552  26.158  43.028  1.00 77.89  ? 207  LEU A O   1 
ATOM   1008  C CB  . LEU A 1 132 ? 78.069  24.403  43.883  1.00 64.58  ? 207  LEU A CB  1 
ATOM   1009  C CG  . LEU A 1 132 ? 79.268  23.605  43.373  1.00 61.50  ? 207  LEU A CG  1 
ATOM   1010  C CD1 . LEU A 1 132 ? 79.458  22.344  44.201  1.00 53.46  ? 207  LEU A CD1 1 
ATOM   1011  C CD2 . LEU A 1 132 ? 79.076  23.258  41.909  1.00 66.72  ? 207  LEU A CD2 1 
ATOM   1012  N N   . SER A 1 133 ? 76.430  27.084  44.885  1.00 63.11  ? 208  SER A N   1 
ATOM   1013  C CA  . SER A 1 133 ? 75.169  27.715  45.256  1.00 62.41  ? 208  SER A CA  1 
ATOM   1014  C C   . SER A 1 133 ? 74.826  28.866  44.323  1.00 68.05  ? 208  SER A C   1 
ATOM   1015  O O   . SER A 1 133 ? 73.647  29.206  44.171  1.00 75.55  ? 208  SER A O   1 
ATOM   1016  C CB  . SER A 1 133 ? 75.229  28.212  46.700  1.00 67.91  ? 208  SER A CB  1 
ATOM   1017  O OG  . SER A 1 133 ? 75.614  29.576  46.751  1.00 69.34  ? 208  SER A OG  1 
ATOM   1018  N N   . ASP A 1 134 ? 75.831  29.484  43.701  1.00 62.22  ? 209  ASP A N   1 
ATOM   1019  C CA  . ASP A 1 134 ? 75.541  30.534  42.729  1.00 71.25  ? 209  ASP A CA  1 
ATOM   1020  C C   . ASP A 1 134 ? 75.141  30.009  41.353  1.00 75.85  ? 209  ASP A C   1 
ATOM   1021  O O   . ASP A 1 134 ? 74.690  30.804  40.520  1.00 83.40  ? 209  ASP A O   1 
ATOM   1022  C CB  . ASP A 1 134 ? 76.741  31.470  42.569  1.00 60.91  ? 209  ASP A CB  1 
ATOM   1023  C CG  . ASP A 1 134 ? 76.329  32.877  42.179  1.00 74.25  ? 209  ASP A CG  1 
ATOM   1024  O OD1 . ASP A 1 134 ? 75.255  33.330  42.630  1.00 72.84  ? 209  ASP A OD1 1 
ATOM   1025  O OD2 . ASP A 1 134 ? 77.072  33.525  41.410  1.00 87.96  ? 209  ASP A OD2 1 
ATOM   1026  N N   . SER A 1 135 ? 75.282  28.711  41.091  1.00 57.46  ? 210  SER A N   1 
ATOM   1027  C CA  . SER A 1 135 ? 75.093  28.195  39.740  1.00 66.31  ? 210  SER A CA  1 
ATOM   1028  C C   . SER A 1 135 ? 73.642  28.302  39.285  1.00 75.55  ? 210  SER A C   1 
ATOM   1029  O O   . SER A 1 135 ? 72.708  28.096  40.065  1.00 72.94  ? 210  SER A O   1 
ATOM   1030  C CB  . SER A 1 135 ? 75.547  26.738  39.662  1.00 74.79  ? 210  SER A CB  1 
ATOM   1031  O OG  . SER A 1 135 ? 75.531  26.275  38.321  1.00 74.47  ? 210  SER A OG  1 
ATOM   1032  N N   . GLN A 1 136 ? 73.460  28.623  38.001  1.00 81.76  ? 211  GLN A N   1 
ATOM   1033  C CA  . GLN A 1 136 ? 72.129  28.581  37.406  1.00 70.99  ? 211  GLN A CA  1 
ATOM   1034  C C   . GLN A 1 136 ? 71.590  27.158  37.351  1.00 74.79  ? 211  GLN A C   1 
ATOM   1035  O O   . GLN A 1 136 ? 70.372  26.953  37.404  1.00 81.63  ? 211  GLN A O   1 
ATOM   1036  C CB  . GLN A 1 136 ? 72.160  29.178  35.999  1.00 83.71  ? 211  GLN A CB  1 
ATOM   1037  C CG  . GLN A 1 136 ? 72.898  30.499  35.888  1.00 97.32  ? 211  GLN A CG  1 
ATOM   1038  C CD  . GLN A 1 136 ? 72.284  31.416  34.850  1.00 98.91  ? 211  GLN A CD  1 
ATOM   1039  O OE1 . GLN A 1 136 ? 72.374  31.160  33.649  1.00 102.77 ? 211  GLN A OE1 1 
ATOM   1040  N NE2 . GLN A 1 136 ? 71.657  32.494  35.308  1.00 92.81  ? 211  GLN A NE2 1 
ATOM   1041  N N   . VAL A 1 137 ? 72.478  26.168  37.233  1.00 72.41  ? 212  VAL A N   1 
ATOM   1042  C CA  . VAL A 1 137 ? 72.057  24.772  37.188  1.00 74.15  ? 212  VAL A CA  1 
ATOM   1043  C C   . VAL A 1 137 ? 71.399  24.408  38.509  1.00 76.41  ? 212  VAL A C   1 
ATOM   1044  O O   . VAL A 1 137 ? 71.992  24.574  39.583  1.00 75.22  ? 212  VAL A O   1 
ATOM   1045  C CB  . VAL A 1 137 ? 73.249  23.860  36.883  1.00 73.46  ? 212  VAL A CB  1 
ATOM   1046  C CG1 . VAL A 1 137 ? 72.853  22.402  37.036  1.00 84.28  ? 212  VAL A CG1 1 
ATOM   1047  C CG2 . VAL A 1 137 ? 73.758  24.121  35.478  1.00 74.88  ? 212  VAL A CG2 1 
ATOM   1048  N N   . ARG A 1 138 ? 70.163  23.908  38.437  1.00 75.33  ? 213  ARG A N   1 
ATOM   1049  C CA  . ARG A 1 138 ? 69.413  23.635  39.660  1.00 80.34  ? 213  ARG A CA  1 
ATOM   1050  C C   . ARG A 1 138 ? 70.030  22.494  40.456  1.00 79.41  ? 213  ARG A C   1 
ATOM   1051  O O   . ARG A 1 138 ? 69.964  22.493  41.688  1.00 83.30  ? 213  ARG A O   1 
ATOM   1052  C CB  . ARG A 1 138 ? 67.955  23.310  39.345  1.00 71.29  ? 213  ARG A CB  1 
ATOM   1053  C CG  . ARG A 1 138 ? 67.075  23.300  40.589  1.00 75.36  ? 213  ARG A CG  1 
ATOM   1054  C CD  . ARG A 1 138 ? 65.654  22.897  40.266  1.00 75.44  ? 213  ARG A CD  1 
ATOM   1055  N NE  . ARG A 1 138 ? 65.060  23.759  39.255  1.00 63.21  ? 213  ARG A NE  1 
ATOM   1056  C CZ  . ARG A 1 138 ? 63.811  23.652  38.829  1.00 76.91  ? 213  ARG A CZ  1 
ATOM   1057  N NH1 . ARG A 1 138 ? 62.996  22.724  39.304  1.00 93.18  ? 213  ARG A NH1 1 
ATOM   1058  N NH2 . ARG A 1 138 ? 63.369  24.494  37.900  1.00 101.26 ? 213  ARG A NH2 1 
ATOM   1059  N N   . ALA A 1 139 ? 70.611  21.503  39.780  1.00 72.92  ? 214  ALA A N   1 
ATOM   1060  C CA  . ALA A 1 139 ? 71.212  20.386  40.503  1.00 71.65  ? 214  ALA A CA  1 
ATOM   1061  C C   . ALA A 1 139 ? 72.333  20.874  41.411  1.00 74.04  ? 214  ALA A C   1 
ATOM   1062  O O   . ALA A 1 139 ? 72.346  20.588  42.618  1.00 79.17  ? 214  ALA A O   1 
ATOM   1063  C CB  . ALA A 1 139 ? 71.729  19.338  39.517  1.00 63.70  ? 214  ALA A CB  1 
ATOM   1064  N N   . PHE A 1 140 ? 73.276  21.628  40.842  1.00 73.54  ? 215  PHE A N   1 
ATOM   1065  C CA  . PHE A 1 140 ? 74.382  22.171  41.621  1.00 72.28  ? 215  PHE A CA  1 
ATOM   1066  C C   . PHE A 1 140 ? 73.870  23.049  42.754  1.00 72.88  ? 215  PHE A C   1 
ATOM   1067  O O   . PHE A 1 140 ? 74.261  22.877  43.912  1.00 77.81  ? 215  PHE A O   1 
ATOM   1068  C CB  . PHE A 1 140 ? 75.322  22.964  40.709  1.00 77.16  ? 215  PHE A CB  1 
ATOM   1069  C CG  . PHE A 1 140 ? 76.134  22.109  39.773  1.00 75.71  ? 215  PHE A CG  1 
ATOM   1070  C CD1 . PHE A 1 140 ? 76.761  20.960  40.225  1.00 81.34  ? 215  PHE A CD1 1 
ATOM   1071  C CD2 . PHE A 1 140 ? 76.278  22.462  38.440  1.00 71.41  ? 215  PHE A CD2 1 
ATOM   1072  C CE1 . PHE A 1 140 ? 77.510  20.176  39.366  1.00 77.77  ? 215  PHE A CE1 1 
ATOM   1073  C CE2 . PHE A 1 140 ? 77.026  21.683  37.577  1.00 77.32  ? 215  PHE A CE2 1 
ATOM   1074  C CZ  . PHE A 1 140 ? 77.642  20.538  38.040  1.00 78.78  ? 215  PHE A CZ  1 
ATOM   1075  N N   . ARG A 1 141 ? 72.983  23.995  42.435  1.00 65.78  ? 216  ARG A N   1 
ATOM   1076  C CA  . ARG A 1 141 ? 72.495  24.936  43.439  1.00 71.20  ? 216  ARG A CA  1 
ATOM   1077  C C   . ARG A 1 141 ? 71.797  24.211  44.585  1.00 70.37  ? 216  ARG A C   1 
ATOM   1078  O O   . ARG A 1 141 ? 72.083  24.462  45.759  1.00 69.66  ? 216  ARG A O   1 
ATOM   1079  C CB  . ARG A 1 141 ? 71.555  25.949  42.783  1.00 64.27  ? 216  ARG A CB  1 
ATOM   1080  C CG  . ARG A 1 141 ? 71.195  27.130  43.663  1.00 66.64  ? 216  ARG A CG  1 
ATOM   1081  C CD  . ARG A 1 141 ? 70.695  28.309  42.836  1.00 63.15  ? 216  ARG A CD  1 
ATOM   1082  N NE  . ARG A 1 141 ? 69.310  28.140  42.412  1.00 62.43  ? 216  ARG A NE  1 
ATOM   1083  C CZ  . ARG A 1 141 ? 68.932  27.679  41.226  1.00 69.52  ? 216  ARG A CZ  1 
ATOM   1084  N NH1 . ARG A 1 141 ? 69.816  27.344  40.299  1.00 69.15  ? 216  ARG A NH1 1 
ATOM   1085  N NH2 . ARG A 1 141 ? 67.635  27.556  40.962  1.00 66.15  ? 216  ARG A NH2 1 
ATOM   1086  N N   . HIS A 1 142 ? 70.888  23.292  44.254  1.00 61.99  ? 217  HIS A N   1 
ATOM   1087  C CA  . HIS A 1 142 ? 70.128  22.546  45.254  1.00 64.76  ? 217  HIS A CA  1 
ATOM   1088  C C   . HIS A 1 142 ? 71.047  21.721  46.149  1.00 69.66  ? 217  HIS A C   1 
ATOM   1089  O O   . HIS A 1 142 ? 71.009  21.834  47.385  1.00 68.06  ? 217  HIS A O   1 
ATOM   1090  C CB  . HIS A 1 142 ? 69.112  21.649  44.534  1.00 62.35  ? 217  HIS A CB  1 
ATOM   1091  C CG  . HIS A 1 142 ? 68.183  20.902  45.443  1.00 61.23  ? 217  HIS A CG  1 
ATOM   1092  N ND1 . HIS A 1 142 ? 67.057  20.258  44.976  1.00 61.97  ? 217  HIS A ND1 1 
ATOM   1093  C CD2 . HIS A 1 142 ? 68.203  20.695  46.782  1.00 71.74  ? 217  HIS A CD2 1 
ATOM   1094  C CE1 . HIS A 1 142 ? 66.428  19.684  45.985  1.00 66.78  ? 217  HIS A CE1 1 
ATOM   1095  N NE2 . HIS A 1 142 ? 67.102  19.934  47.093  1.00 63.02  ? 217  HIS A NE2 1 
ATOM   1096  N N   . THR A 1 143 ? 71.859  20.851  45.538  1.00 69.06  ? 218  THR A N   1 
ATOM   1097  C CA  . THR A 1 143 ? 72.730  19.988  46.327  1.00 57.63  ? 218  THR A CA  1 
ATOM   1098  C C   . THR A 1 143 ? 73.684  20.811  47.185  1.00 58.04  ? 218  THR A C   1 
ATOM   1099  O O   . THR A 1 143 ? 73.865  20.526  48.378  1.00 64.93  ? 218  THR A O   1 
ATOM   1100  C CB  . THR A 1 143 ? 73.504  19.044  45.407  1.00 51.89  ? 218  THR A CB  1 
ATOM   1101  O OG1 . THR A 1 143 ? 72.621  18.515  44.407  1.00 72.25  ? 218  THR A OG1 1 
ATOM   1102  C CG2 . THR A 1 143 ? 74.094  17.897  46.201  1.00 59.16  ? 218  THR A CG2 1 
ATOM   1103  N N   . SER A 1 144 ? 74.278  21.858  46.605  1.00 62.03  ? 219  SER A N   1 
ATOM   1104  C CA  . SER A 1 144 ? 75.230  22.679  47.339  1.00 64.80  ? 219  SER A CA  1 
ATOM   1105  C C   . SER A 1 144 ? 74.560  23.423  48.482  1.00 62.30  ? 219  SER A C   1 
ATOM   1106  O O   . SER A 1 144 ? 75.152  23.583  49.552  1.00 66.87  ? 219  SER A O   1 
ATOM   1107  C CB  . SER A 1 144 ? 75.900  23.669  46.391  1.00 61.45  ? 219  SER A CB  1 
ATOM   1108  O OG  . SER A 1 144 ? 76.578  24.685  47.107  1.00 93.64  ? 219  SER A OG  1 
ATOM   1109  N N   . THR A 1 145 ? 73.326  23.889  48.279  1.00 50.50  ? 220  THR A N   1 
ATOM   1110  C CA  . THR A 1 145 ? 72.635  24.609  49.340  1.00 54.21  ? 220  THR A CA  1 
ATOM   1111  C C   . THR A 1 145 ? 72.315  23.684  50.505  1.00 61.29  ? 220  THR A C   1 
ATOM   1112  O O   . THR A 1 145 ? 72.513  24.053  51.671  1.00 65.13  ? 220  THR A O   1 
ATOM   1113  C CB  . THR A 1 145 ? 71.360  25.252  48.795  1.00 54.39  ? 220  THR A CB  1 
ATOM   1114  O OG1 . THR A 1 145 ? 71.700  26.203  47.780  1.00 57.17  ? 220  THR A OG1 1 
ATOM   1115  C CG2 . THR A 1 145 ? 70.610  25.963  49.911  1.00 40.53  ? 220  THR A CG2 1 
ATOM   1116  N N   . LEU A 1 146 ? 71.821  22.476  50.213  1.00 61.67  ? 221  LEU A N   1 
ATOM   1117  C CA  . LEU A 1 146 ? 71.579  21.519  51.290  1.00 59.70  ? 221  LEU A CA  1 
ATOM   1118  C C   . LEU A 1 146 ? 72.871  21.197  52.033  1.00 64.38  ? 221  LEU A C   1 
ATOM   1119  O O   . LEU A 1 146 ? 72.896  21.152  53.274  1.00 66.83  ? 221  LEU A O   1 
ATOM   1120  C CB  . LEU A 1 146 ? 70.946  20.241  50.741  1.00 54.89  ? 221  LEU A CB  1 
ATOM   1121  C CG  . LEU A 1 146 ? 70.901  19.082  51.742  1.00 49.51  ? 221  LEU A CG  1 
ATOM   1122  C CD1 . LEU A 1 146 ? 69.707  19.224  52.672  1.00 40.98  ? 221  LEU A CD1 1 
ATOM   1123  C CD2 . LEU A 1 146 ? 70.876  17.742  51.030  1.00 50.12  ? 221  LEU A CD2 1 
ATOM   1124  N N   . ALA A 1 147 ? 73.959  20.982  51.286  1.00 57.63  ? 222  ALA A N   1 
ATOM   1125  C CA  . ALA A 1 147 ? 75.240  20.681  51.911  1.00 53.51  ? 222  ALA A CA  1 
ATOM   1126  C C   . ALA A 1 147 ? 75.718  21.835  52.783  1.00 59.88  ? 222  ALA A C   1 
ATOM   1127  O O   . ALA A 1 147 ? 76.244  21.616  53.879  1.00 56.51  ? 222  ALA A O   1 
ATOM   1128  C CB  . ALA A 1 147 ? 76.280  20.349  50.842  1.00 51.97  ? 222  ALA A CB  1 
ATOM   1129  N N   . ALA A 1 148 ? 75.536  23.071  52.315  1.00 62.60  ? 223  ALA A N   1 
ATOM   1130  C CA  . ALA A 1 148 ? 75.996  24.232  53.070  1.00 55.22  ? 223  ALA A CA  1 
ATOM   1131  C C   . ALA A 1 148 ? 75.183  24.417  54.342  1.00 58.50  ? 223  ALA A C   1 
ATOM   1132  O O   . ALA A 1 148 ? 75.733  24.773  55.391  1.00 62.14  ? 223  ALA A O   1 
ATOM   1133  C CB  . ALA A 1 148 ? 75.925  25.485  52.198  1.00 40.89  ? 223  ALA A CB  1 
ATOM   1134  N N   . MET A 1 149 ? 73.874  24.165  54.275  1.00 56.05  ? 224  MET A N   1 
ATOM   1135  C CA  . MET A 1 149 ? 73.057  24.269  55.480  1.00 59.85  ? 224  MET A CA  1 
ATOM   1136  C C   . MET A 1 149 ? 73.443  23.206  56.504  1.00 62.76  ? 224  MET A C   1 
ATOM   1137  O O   . MET A 1 149 ? 73.561  23.502  57.702  1.00 62.86  ? 224  MET A O   1 
ATOM   1138  C CB  . MET A 1 149 ? 71.577  24.173  55.120  1.00 48.83  ? 224  MET A CB  1 
ATOM   1139  C CG  . MET A 1 149 ? 71.116  25.239  54.146  1.00 52.61  ? 224  MET A CG  1 
ATOM   1140  S SD  . MET A 1 149 ? 70.971  26.858  54.919  1.00 66.03  ? 224  MET A SD  1 
ATOM   1141  C CE  . MET A 1 149 ? 72.382  27.704  54.209  1.00 53.23  ? 224  MET A CE  1 
ATOM   1142  N N   . LYS A 1 150 ? 73.659  21.967  56.052  1.00 56.65  ? 225  LYS A N   1 
ATOM   1143  C CA  . LYS A 1 150 ? 74.097  20.921  56.974  1.00 60.50  ? 225  LYS A CA  1 
ATOM   1144  C C   . LYS A 1 150 ? 75.456  21.260  57.581  1.00 57.98  ? 225  LYS A C   1 
ATOM   1145  O O   . LYS A 1 150 ? 75.673  21.090  58.793  1.00 60.39  ? 225  LYS A O   1 
ATOM   1146  C CB  . LYS A 1 150 ? 74.151  19.578  56.245  1.00 53.73  ? 225  LYS A CB  1 
ATOM   1147  C CG  . LYS A 1 150 ? 72.785  19.027  55.846  1.00 52.61  ? 225  LYS A CG  1 
ATOM   1148  C CD  . LYS A 1 150 ? 71.717  19.352  56.880  1.00 52.00  ? 225  LYS A CD  1 
ATOM   1149  C CE  . LYS A 1 150 ? 70.453  18.549  56.633  1.00 59.28  ? 225  LYS A CE  1 
ATOM   1150  N NZ  . LYS A 1 150 ? 69.637  18.420  57.869  1.00 67.07  ? 225  LYS A NZ  1 
ATOM   1151  N N   . LEU A 1 151 ? 76.379  21.748  56.747  1.00 52.60  ? 226  LEU A N   1 
ATOM   1152  C CA  . LEU A 1 151 ? 77.693  22.172  57.216  1.00 48.18  ? 226  LEU A CA  1 
ATOM   1153  C C   . LEU A 1 151 ? 77.586  23.253  58.281  1.00 58.09  ? 226  LEU A C   1 
ATOM   1154  O O   . LEU A 1 151 ? 78.290  23.204  59.297  1.00 68.15  ? 226  LEU A O   1 
ATOM   1155  C CB  . LEU A 1 151 ? 78.521  22.668  56.031  1.00 49.87  ? 226  LEU A CB  1 
ATOM   1156  C CG  . LEU A 1 151 ? 79.879  23.311  56.308  1.00 56.80  ? 226  LEU A CG  1 
ATOM   1157  C CD1 . LEU A 1 151 ? 80.776  22.370  57.075  1.00 48.70  ? 226  LEU A CD1 1 
ATOM   1158  C CD2 . LEU A 1 151 ? 80.536  23.725  55.002  1.00 52.22  ? 226  LEU A CD2 1 
ATOM   1159  N N   . MET A 1 152 ? 76.716  24.243  58.069  1.00 58.30  ? 227  MET A N   1 
ATOM   1160  C CA  . MET A 1 152 ? 76.596  25.305  59.059  1.00 59.16  ? 227  MET A CA  1 
ATOM   1161  C C   . MET A 1 152 ? 75.942  24.811  60.341  1.00 56.05  ? 227  MET A C   1 
ATOM   1162  O O   . MET A 1 152 ? 76.291  25.282  61.423  1.00 61.88  ? 227  MET A O   1 
ATOM   1163  C CB  . MET A 1 152 ? 75.826  26.500  58.497  1.00 49.37  ? 227  MET A CB  1 
ATOM   1164  C CG  . MET A 1 152 ? 75.714  27.617  59.518  1.00 41.60  ? 227  MET A CG  1 
ATOM   1165  S SD  . MET A 1 152 ? 75.785  29.302  58.901  1.00 57.29  ? 227  MET A SD  1 
ATOM   1166  C CE  . MET A 1 152 ? 75.545  30.196  60.434  1.00 60.55  ? 227  MET A CE  1 
ATOM   1167  N N   . THR A 1 153 ? 75.000  23.871  60.251  1.00 51.50  ? 228  THR A N   1 
ATOM   1168  C CA  . THR A 1 153 ? 74.461  23.268  61.470  1.00 61.50  ? 228  THR A CA  1 
ATOM   1169  C C   . THR A 1 153 ? 75.570  22.608  62.287  1.00 60.13  ? 228  THR A C   1 
ATOM   1170  O O   . THR A 1 153 ? 75.686  22.823  63.506  1.00 58.11  ? 228  THR A O   1 
ATOM   1171  C CB  . THR A 1 153 ? 73.369  22.260  61.109  1.00 61.59  ? 228  THR A CB  1 
ATOM   1172  O OG1 . THR A 1 153 ? 72.370  22.905  60.312  1.00 60.14  ? 228  THR A OG1 1 
ATOM   1173  C CG2 . THR A 1 153 ? 72.727  21.679  62.358  1.00 55.54  ? 228  THR A CG2 1 
ATOM   1174  N N   . ALA A 1 154 ? 76.404  21.803  61.622  1.00 47.24  ? 229  ALA A N   1 
ATOM   1175  C CA  . ALA A 1 154 ? 77.531  21.185  62.315  1.00 52.91  ? 229  ALA A CA  1 
ATOM   1176  C C   . ALA A 1 154 ? 78.459  22.240  62.915  1.00 58.88  ? 229  ALA A C   1 
ATOM   1177  O O   . ALA A 1 154 ? 78.920  22.100  64.057  1.00 61.58  ? 229  ALA A O   1 
ATOM   1178  C CB  . ALA A 1 154 ? 78.294  20.271  61.359  1.00 49.24  ? 229  ALA A CB  1 
ATOM   1179  N N   . LEU A 1 155 ? 78.725  23.315  62.167  1.00 54.94  ? 230  LEU A N   1 
ATOM   1180  C CA  . LEU A 1 155 ? 79.610  24.364  62.669  1.00 54.12  ? 230  LEU A CA  1 
ATOM   1181  C C   . LEU A 1 155 ? 79.000  25.083  63.866  1.00 54.37  ? 230  LEU A C   1 
ATOM   1182  O O   . LEU A 1 155 ? 79.720  25.503  64.779  1.00 58.76  ? 230  LEU A O   1 
ATOM   1183  C CB  . LEU A 1 155 ? 79.929  25.365  61.560  1.00 43.80  ? 230  LEU A CB  1 
ATOM   1184  C CG  . LEU A 1 155 ? 80.805  24.846  60.424  1.00 52.13  ? 230  LEU A CG  1 
ATOM   1185  C CD1 . LEU A 1 155 ? 80.939  25.891  59.329  1.00 56.86  ? 230  LEU A CD1 1 
ATOM   1186  C CD2 . LEU A 1 155 ? 82.160  24.443  60.958  1.00 39.84  ? 230  LEU A CD2 1 
ATOM   1187  N N   . VAL A 1 156 ? 77.677  25.249  63.871  1.00 55.81  ? 231  VAL A N   1 
ATOM   1188  C CA  . VAL A 1 156 ? 77.005  25.859  65.013  1.00 53.32  ? 231  VAL A CA  1 
ATOM   1189  C C   . VAL A 1 156 ? 77.171  24.986  66.244  1.00 57.24  ? 231  VAL A C   1 
ATOM   1190  O O   . VAL A 1 156 ? 77.410  25.486  67.351  1.00 55.19  ? 231  VAL A O   1 
ATOM   1191  C CB  . VAL A 1 156 ? 75.520  26.115  64.695  1.00 42.47  ? 231  VAL A CB  1 
ATOM   1192  C CG1 . VAL A 1 156 ? 74.769  26.521  65.951  1.00 45.19  ? 231  VAL A CG1 1 
ATOM   1193  C CG2 . VAL A 1 156 ? 75.387  27.202  63.648  1.00 47.31  ? 231  VAL A CG2 1 
ATOM   1194  N N   . ASN A 1 157 ? 77.058  23.666  66.074  1.00 61.53  ? 232  ASN A N   1 
ATOM   1195  C CA  . ASN A 1 157 ? 77.292  22.784  67.217  1.00 62.78  ? 232  ASN A CA  1 
ATOM   1196  C C   . ASN A 1 157 ? 78.734  22.894  67.709  1.00 65.77  ? 232  ASN A C   1 
ATOM   1197  O O   . ASN A 1 157 ? 78.986  22.919  68.922  1.00 60.37  ? 232  ASN A O   1 
ATOM   1198  C CB  . ASN A 1 157 ? 76.953  21.337  66.864  1.00 56.70  ? 232  ASN A CB  1 
ATOM   1199  C CG  . ASN A 1 157 ? 77.176  20.392  68.032  1.00 66.71  ? 232  ASN A CG  1 
ATOM   1200  O OD1 . ASN A 1 157 ? 77.831  19.359  67.896  1.00 94.78  ? 232  ASN A OD1 1 
ATOM   1201  N ND2 . ASN A 1 157 ? 76.641  20.752  69.195  1.00 66.01  ? 232  ASN A ND2 1 
ATOM   1202  N N   . VAL A 1 158 ? 79.692  22.969  66.780  1.00 56.56  ? 233  VAL A N   1 
ATOM   1203  C CA  . VAL A 1 158 ? 81.095  23.116  67.174  1.00 55.17  ? 233  VAL A CA  1 
ATOM   1204  C C   . VAL A 1 158 ? 81.299  24.406  67.961  1.00 51.47  ? 233  VAL A C   1 
ATOM   1205  O O   . VAL A 1 158 ? 81.967  24.422  69.002  1.00 49.27  ? 233  VAL A O   1 
ATOM   1206  C CB  . VAL A 1 158 ? 82.017  23.059  65.944  1.00 49.85  ? 233  VAL A CB  1 
ATOM   1207  C CG1 . VAL A 1 158 ? 83.467  23.159  66.377  1.00 42.70  ? 233  VAL A CG1 1 
ATOM   1208  C CG2 . VAL A 1 158 ? 81.801  21.766  65.184  1.00 62.14  ? 233  VAL A CG2 1 
ATOM   1209  N N   . ALA A 1 159 ? 80.720  25.508  67.477  1.00 53.85  ? 234  ALA A N   1 
ATOM   1210  C CA  . ALA A 1 159 ? 80.896  26.794  68.148  1.00 57.29  ? 234  ALA A CA  1 
ATOM   1211  C C   . ALA A 1 159 ? 80.221  26.801  69.514  1.00 62.53  ? 234  ALA A C   1 
ATOM   1212  O O   . ALA A 1 159 ? 80.727  27.410  70.466  1.00 71.86  ? 234  ALA A O   1 
ATOM   1213  C CB  . ALA A 1 159 ? 80.353  27.921  67.269  1.00 50.80  ? 234  ALA A CB  1 
ATOM   1214  N N   . LEU A 1 160 ? 79.075  26.129  69.631  1.00 52.56  ? 235  LEU A N   1 
ATOM   1215  C CA  . LEU A 1 160 ? 78.400  26.023  70.919  1.00 55.34  ? 235  LEU A CA  1 
ATOM   1216  C C   . LEU A 1 160 ? 79.258  25.257  71.918  1.00 56.40  ? 235  LEU A C   1 
ATOM   1217  O O   . LEU A 1 160 ? 79.399  25.665  73.080  1.00 53.50  ? 235  LEU A O   1 
ATOM   1218  C CB  . LEU A 1 160 ? 77.044  25.344  70.728  1.00 63.49  ? 235  LEU A CB  1 
ATOM   1219  C CG  . LEU A 1 160 ? 76.323  24.838  71.974  1.00 54.27  ? 235  LEU A CG  1 
ATOM   1220  C CD1 . LEU A 1 160 ? 75.822  26.007  72.801  1.00 46.56  ? 235  LEU A CD1 1 
ATOM   1221  C CD2 . LEU A 1 160 ? 75.177  23.918  71.585  1.00 59.29  ? 235  LEU A CD2 1 
ATOM   1222  N N   . ASN A 1 161 ? 79.845  24.140  71.479  1.00 60.46  ? 236  ASN A N   1 
ATOM   1223  C CA  . ASN A 1 161 ? 80.756  23.401  72.349  1.00 51.33  ? 236  ASN A CA  1 
ATOM   1224  C C   . ASN A 1 161 ? 81.954  24.255  72.739  1.00 61.37  ? 236  ASN A C   1 
ATOM   1225  O O   . ASN A 1 161 ? 82.427  24.192  73.881  1.00 74.96  ? 236  ASN A O   1 
ATOM   1226  C CB  . ASN A 1 161 ? 81.224  22.115  71.669  1.00 59.92  ? 236  ASN A CB  1 
ATOM   1227  C CG  . ASN A 1 161 ? 80.078  21.211  71.272  1.00 72.62  ? 236  ASN A CG  1 
ATOM   1228  O OD1 . ASN A 1 161 ? 79.073  21.112  71.976  1.00 71.77  ? 236  ASN A OD1 1 
ATOM   1229  N ND2 . ASN A 1 161 ? 80.226  20.537  70.137  1.00 81.48  ? 236  ASN A ND2 1 
ATOM   1230  N N   . LEU A 1 162 ? 82.465  25.056  71.798  1.00 59.05  ? 237  LEU A N   1 
ATOM   1231  C CA  . LEU A 1 162 ? 83.582  25.943  72.113  1.00 62.30  ? 237  LEU A CA  1 
ATOM   1232  C C   . LEU A 1 162 ? 83.193  26.956  73.180  1.00 59.78  ? 237  LEU A C   1 
ATOM   1233  O O   . LEU A 1 162 ? 83.973  27.230  74.098  1.00 53.02  ? 237  LEU A O   1 
ATOM   1234  C CB  . LEU A 1 162 ? 84.071  26.658  70.855  1.00 56.20  ? 237  LEU A CB  1 
ATOM   1235  C CG  . LEU A 1 162 ? 84.837  25.820  69.834  1.00 58.65  ? 237  LEU A CG  1 
ATOM   1236  C CD1 . LEU A 1 162 ? 85.059  26.620  68.564  1.00 62.31  ? 237  LEU A CD1 1 
ATOM   1237  C CD2 . LEU A 1 162 ? 86.161  25.364  70.417  1.00 62.26  ? 237  LEU A CD2 1 
ATOM   1238  N N   . SER A 1 163 ? 81.987  27.518  73.079  1.00 60.26  ? 238  SER A N   1 
ATOM   1239  C CA  . SER A 1 163 ? 81.544  28.485  74.078  1.00 67.01  ? 238  SER A CA  1 
ATOM   1240  C C   . SER A 1 163 ? 81.388  27.831  75.447  1.00 62.95  ? 238  SER A C   1 
ATOM   1241  O O   . SER A 1 163 ? 81.767  28.416  76.470  1.00 72.93  ? 238  SER A O   1 
ATOM   1242  C CB  . SER A 1 163 ? 80.234  29.137  73.640  1.00 57.57  ? 238  SER A CB  1 
ATOM   1243  O OG  . SER A 1 163 ? 79.134  28.281  73.888  1.00 65.57  ? 238  SER A OG  1 
ATOM   1244  N N   . ILE A 1 164 ? 80.841  26.614  75.486  1.00 57.66  ? 239  ILE A N   1 
ATOM   1245  C CA  . ILE A 1 164 ? 80.696  25.911  76.762  1.00 61.07  ? 239  ILE A CA  1 
ATOM   1246  C C   . ILE A 1 164 ? 82.065  25.642  77.379  1.00 72.83  ? 239  ILE A C   1 
ATOM   1247  O O   . ILE A 1 164 ? 82.285  25.864  78.578  1.00 76.07  ? 239  ILE A O   1 
ATOM   1248  C CB  . ILE A 1 164 ? 79.896  24.609  76.576  1.00 54.70  ? 239  ILE A CB  1 
ATOM   1249  C CG1 . ILE A 1 164 ? 78.515  24.910  75.996  1.00 53.06  ? 239  ILE A CG1 1 
ATOM   1250  C CG2 . ILE A 1 164 ? 79.765  23.871  77.896  1.00 55.98  ? 239  ILE A CG2 1 
ATOM   1251  C CD1 . ILE A 1 164 ? 77.871  23.726  75.314  1.00 46.57  ? 239  ILE A CD1 1 
ATOM   1252  N N   . ASN A 1 165 ? 83.009  25.164  76.564  1.00 66.93  ? 240  ASN A N   1 
ATOM   1253  C CA  . ASN A 1 165 ? 84.345  24.862  77.067  1.00 67.55  ? 240  ASN A CA  1 
ATOM   1254  C C   . ASN A 1 165 ? 85.054  26.127  77.539  1.00 76.92  ? 240  ASN A C   1 
ATOM   1255  O O   . ASN A 1 165 ? 85.798  26.105  78.528  1.00 86.99  ? 240  ASN A O   1 
ATOM   1256  C CB  . ASN A 1 165 ? 85.152  24.160  75.975  1.00 65.90  ? 240  ASN A CB  1 
ATOM   1257  C CG  . ASN A 1 165 ? 86.430  23.545  76.497  1.00 106.11 ? 240  ASN A CG  1 
ATOM   1258  O OD1 . ASN A 1 165 ? 86.544  23.231  77.682  1.00 114.23 ? 240  ASN A OD1 1 
ATOM   1259  N ND2 . ASN A 1 165 ? 87.402  23.366  75.611  1.00 113.90 ? 240  ASN A ND2 1 
ATOM   1260  N N   . MET A 1 166 ? 84.828  27.241  76.843  1.00 69.47  ? 241  MET A N   1 
ATOM   1261  C CA  . MET A 1 166 ? 85.380  28.523  77.267  1.00 65.59  ? 241  MET A CA  1 
ATOM   1262  C C   . MET A 1 166 ? 84.821  28.946  78.618  1.00 70.02  ? 241  MET A C   1 
ATOM   1263  O O   . MET A 1 166 ? 85.566  29.398  79.497  1.00 90.72  ? 241  MET A O   1 
ATOM   1264  C CB  . MET A 1 166 ? 85.086  29.576  76.202  1.00 59.88  ? 241  MET A CB  1 
ATOM   1265  C CG  . MET A 1 166 ? 86.308  30.299  75.688  1.00 65.45  ? 241  MET A CG  1 
ATOM   1266  S SD  . MET A 1 166 ? 85.915  31.227  74.201  1.00 95.61  ? 241  MET A SD  1 
ATOM   1267  C CE  . MET A 1 166 ? 85.417  29.876  73.135  1.00 75.16  ? 241  MET A CE  1 
ATOM   1268  N N   . ASP A 1 167 ? 83.504  28.828  78.795  1.00 67.02  ? 242  ASP A N   1 
ATOM   1269  C CA  . ASP A 1 167 ? 82.913  29.142  80.091  1.00 73.29  ? 242  ASP A CA  1 
ATOM   1270  C C   . ASP A 1 167 ? 83.495  28.253  81.184  1.00 83.12  ? 242  ASP A C   1 
ATOM   1271  O O   . ASP A 1 167 ? 83.747  28.714  82.304  1.00 91.46  ? 242  ASP A O   1 
ATOM   1272  C CB  . ASP A 1 167 ? 81.392  28.996  80.029  1.00 76.29  ? 242  ASP A CB  1 
ATOM   1273  C CG  . ASP A 1 167 ? 80.761  29.910  78.997  1.00 84.26  ? 242  ASP A CG  1 
ATOM   1274  O OD1 . ASP A 1 167 ? 81.400  30.916  78.622  1.00 86.86  ? 242  ASP A OD1 1 
ATOM   1275  O OD2 . ASP A 1 167 ? 79.626  29.621  78.560  1.00 87.65  ? 242  ASP A OD2 1 
ATOM   1276  N N   . ASN A 1 168 ? 83.733  26.978  80.869  1.00 78.33  ? 243  ASN A N   1 
ATOM   1277  C CA  . ASN A 1 168 ? 84.297  26.070  81.864  1.00 80.09  ? 243  ASN A CA  1 
ATOM   1278  C C   . ASN A 1 168 ? 85.717  26.477  82.243  1.00 91.69  ? 243  ASN A C   1 
ATOM   1279  O O   . ASN A 1 168 ? 86.079  26.458  83.426  1.00 102.36 ? 243  ASN A O   1 
ATOM   1280  C CB  . ASN A 1 168 ? 84.270  24.634  81.346  1.00 82.37  ? 243  ASN A CB  1 
ATOM   1281  C CG  . ASN A 1 168 ? 84.761  23.638  82.377  1.00 107.76 ? 243  ASN A CG  1 
ATOM   1282  O OD1 . ASN A 1 168 ? 84.565  23.827  83.577  1.00 120.79 ? 243  ASN A OD1 1 
ATOM   1283  N ND2 . ASN A 1 168 ? 85.399  22.568  81.914  1.00 112.07 ? 243  ASN A ND2 1 
ATOM   1284  N N   . THR A 1 169 ? 86.539  26.844  81.254  1.00 84.28  ? 244  THR A N   1 
ATOM   1285  C CA  . THR A 1 169 ? 87.901  27.271  81.565  1.00 89.63  ? 244  THR A CA  1 
ATOM   1286  C C   . THR A 1 169 ? 87.903  28.581  82.345  1.00 85.45  ? 244  THR A C   1 
ATOM   1287  O O   . THR A 1 169 ? 88.746  28.782  83.227  1.00 89.18  ? 244  THR A O   1 
ATOM   1288  C CB  . THR A 1 169 ? 88.737  27.405  80.290  1.00 75.89  ? 244  THR A CB  1 
ATOM   1289  O OG1 . THR A 1 169 ? 88.200  28.445  79.462  1.00 92.11  ? 244  THR A OG1 1 
ATOM   1290  C CG2 . THR A 1 169 ? 88.777  26.089  79.527  1.00 70.58  ? 244  THR A CG2 1 
ATOM   1291  N N   . GLN A 1 170 ? 86.962  29.482  82.047  1.00 70.25  ? 245  GLN A N   1 
ATOM   1292  C CA  . GLN A 1 170 ? 86.872  30.716  82.824  1.00 81.38  ? 245  GLN A CA  1 
ATOM   1293  C C   . GLN A 1 170 ? 86.459  30.428  84.263  1.00 88.54  ? 245  GLN A C   1 
ATOM   1294  O O   . GLN A 1 170 ? 86.970  31.054  85.198  1.00 101.92 ? 245  GLN A O   1 
ATOM   1295  C CB  . GLN A 1 170 ? 85.897  31.698  82.173  1.00 77.52  ? 245  GLN A CB  1 
ATOM   1296  C CG  . GLN A 1 170 ? 85.690  32.958  82.998  1.00 84.96  ? 245  GLN A CG  1 
ATOM   1297  C CD  . GLN A 1 170 ? 84.968  34.057  82.248  1.00 101.37 ? 245  GLN A CD  1 
ATOM   1298  O OE1 . GLN A 1 170 ? 84.237  33.799  81.291  1.00 141.30 ? 245  GLN A OE1 1 
ATOM   1299  N NE2 . GLN A 1 170 ? 85.172  35.296  82.679  1.00 104.42 ? 245  GLN A NE2 1 
ATOM   1300  N N   . ARG A 1 171 ? 85.549  29.471  84.462  1.00 94.84  ? 246  ARG A N   1 
ATOM   1301  C CA  . ARG A 1 171 ? 85.162  29.088  85.818  1.00 110.63 ? 246  ARG A CA  1 
ATOM   1302  C C   . ARG A 1 171 ? 86.338  28.469  86.566  1.00 107.50 ? 246  ARG A C   1 
ATOM   1303  O O   . ARG A 1 171 ? 86.538  28.733  87.759  1.00 118.44 ? 246  ARG A O   1 
ATOM   1304  C CB  . ARG A 1 171 ? 83.983  28.114  85.766  1.00 122.62 ? 246  ARG A CB  1 
ATOM   1305  C CG  . ARG A 1 171 ? 83.510  27.564  87.113  1.00 135.14 ? 246  ARG A CG  1 
ATOM   1306  C CD  . ARG A 1 171 ? 82.854  28.625  88.001  1.00 159.13 ? 246  ARG A CD  1 
ATOM   1307  N NE  . ARG A 1 171 ? 83.800  29.484  88.704  1.00 178.23 ? 246  ARG A NE  1 
ATOM   1308  C CZ  . ARG A 1 171 ? 84.243  29.259  89.934  1.00 196.75 ? 246  ARG A CZ  1 
ATOM   1309  N NH1 . ARG A 1 171 ? 83.882  28.183  90.613  1.00 206.37 ? 246  ARG A NH1 1 
ATOM   1310  N NH2 . ARG A 1 171 ? 85.068  30.136  90.499  1.00 205.92 ? 246  ARG A NH2 1 
ATOM   1311  N N   . GLN A 1 172 ? 87.125  27.637  85.878  1.00 100.48 ? 247  GLN A N   1 
ATOM   1312  C CA  . GLN A 1 172 ? 88.312  27.052  86.496  1.00 98.22  ? 247  GLN A CA  1 
ATOM   1313  C C   . GLN A 1 172 ? 89.315  28.130  86.887  1.00 100.11 ? 247  GLN A C   1 
ATOM   1314  O O   . GLN A 1 172 ? 89.894  28.086  87.980  1.00 106.31 ? 247  GLN A O   1 
ATOM   1315  C CB  . GLN A 1 172 ? 88.963  26.047  85.546  1.00 79.73  ? 247  GLN A CB  1 
ATOM   1316  C CG  . GLN A 1 172 ? 88.122  24.824  85.232  1.00 80.84  ? 247  GLN A CG  1 
ATOM   1317  C CD  . GLN A 1 172 ? 88.642  24.068  84.025  1.00 81.24  ? 247  GLN A CD  1 
ATOM   1318  O OE1 . GLN A 1 172 ? 87.989  24.013  82.983  1.00 113.99 ? 247  GLN A OE1 1 
ATOM   1319  N NE2 . GLN A 1 172 ? 89.824  23.478  84.160  1.00 70.47  ? 247  GLN A NE2 1 
ATOM   1320  N N   . TYR A 1 173 ? 89.539  29.103  85.998  1.00 97.17  ? 248  TYR A N   1 
ATOM   1321  C CA  . TYR A 1 173 ? 90.433  30.211  86.319  1.00 92.06  ? 248  TYR A CA  1 
ATOM   1322  C C   . TYR A 1 173 ? 89.900  31.030  87.484  1.00 99.00  ? 248  TYR A C   1 
ATOM   1323  O O   . TYR A 1 173 ? 90.674  31.525  88.306  1.00 108.21 ? 248  TYR A O   1 
ATOM   1324  C CB  . TYR A 1 173 ? 90.635  31.107  85.098  1.00 96.86  ? 248  TYR A CB  1 
ATOM   1325  C CG  . TYR A 1 173 ? 91.180  32.471  85.457  1.00 89.65  ? 248  TYR A CG  1 
ATOM   1326  C CD1 . TYR A 1 173 ? 92.480  32.619  85.925  1.00 95.75  ? 248  TYR A CD1 1 
ATOM   1327  C CD2 . TYR A 1 173 ? 90.385  33.605  85.359  1.00 84.80  ? 248  TYR A CD2 1 
ATOM   1328  C CE1 . TYR A 1 173 ? 92.980  33.862  86.266  1.00 92.36  ? 248  TYR A CE1 1 
ATOM   1329  C CE2 . TYR A 1 173 ? 90.876  34.853  85.699  1.00 102.59 ? 248  TYR A CE2 1 
ATOM   1330  C CZ  . TYR A 1 173 ? 92.174  34.975  86.152  1.00 99.11  ? 248  TYR A CZ  1 
ATOM   1331  O OH  . TYR A 1 173 ? 92.667  36.215  86.491  1.00 88.93  ? 248  TYR A OH  1 
ATOM   1332  N N   . GLU A 1 174 ? 88.579  31.195  87.562  1.00 104.79 ? 249  GLU A N   1 
ATOM   1333  C CA  . GLU A 1 174 ? 87.982  31.924  88.676  1.00 115.17 ? 249  GLU A CA  1 
ATOM   1334  C C   . GLU A 1 174 ? 88.228  31.195  89.992  1.00 114.21 ? 249  GLU A C   1 
ATOM   1335  O O   . GLU A 1 174 ? 88.597  31.813  91.000  1.00 125.80 ? 249  GLU A O   1 
ATOM   1336  C CB  . GLU A 1 174 ? 86.485  32.108  88.414  1.00 121.14 ? 249  GLU A CB  1 
ATOM   1337  C CG  . GLU A 1 174 ? 85.894  33.430  88.876  1.00 146.37 ? 249  GLU A CG  1 
ATOM   1338  C CD  . GLU A 1 174 ? 86.051  33.660  90.365  1.00 167.10 ? 249  GLU A CD  1 
ATOM   1339  O OE1 . GLU A 1 174 ? 85.462  32.891  91.152  1.00 172.85 ? 249  GLU A OE1 1 
ATOM   1340  O OE2 . GLU A 1 174 ? 86.751  34.621  90.746  1.00 174.38 ? 249  GLU A OE2 1 
ATOM   1341  N N   . ALA A 1 175 ? 88.049  29.872  89.991  1.00 110.95 ? 250  ALA A N   1 
ATOM   1342  C CA  . ALA A 1 175 ? 88.326  29.084  91.188  1.00 106.00 ? 250  ALA A CA  1 
ATOM   1343  C C   . ALA A 1 175 ? 89.798  29.165  91.576  1.00 119.81 ? 250  ALA A C   1 
ATOM   1344  O O   . ALA A 1 175 ? 90.130  29.286  92.761  1.00 133.37 ? 250  ALA A O   1 
ATOM   1345  C CB  . ALA A 1 175 ? 87.906  27.630  90.970  1.00 99.63  ? 250  ALA A CB  1 
ATOM   1346  N N   . GLU A 1 176 ? 90.697  29.099  90.589  1.00 122.62 ? 251  GLU A N   1 
ATOM   1347  C CA  . GLU A 1 176 ? 92.125  29.194  90.880  1.00 104.69 ? 251  GLU A CA  1 
ATOM   1348  C C   . GLU A 1 176 ? 92.491  30.575  91.410  1.00 114.66 ? 251  GLU A C   1 
ATOM   1349  O O   . GLU A 1 176 ? 93.343  30.701  92.298  1.00 135.64 ? 251  GLU A O   1 
ATOM   1350  C CB  . GLU A 1 176 ? 92.937  28.867  89.625  1.00 110.34 ? 251  GLU A CB  1 
ATOM   1351  C CG  . GLU A 1 176 ? 93.266  27.386  89.441  1.00 120.23 ? 251  GLU A CG  1 
ATOM   1352  C CD  . GLU A 1 176 ? 94.372  26.885  90.359  1.00 127.57 ? 251  GLU A CD  1 
ATOM   1353  O OE1 . GLU A 1 176 ? 94.956  25.826  90.048  1.00 130.96 ? 251  GLU A OE1 1 
ATOM   1354  O OE2 . GLU A 1 176 ? 94.674  27.546  91.373  1.00 138.08 ? 251  GLU A OE2 1 
ATOM   1355  N N   . ARG A 1 177 ? 91.859  31.621  90.873  1.00 111.26 ? 252  ARG A N   1 
ATOM   1356  C CA  . ARG A 1 177 ? 92.089  32.979  91.353  1.00 113.02 ? 252  ARG A CA  1 
ATOM   1357  C C   . ARG A 1 177 ? 91.621  33.134  92.792  1.00 117.42 ? 252  ARG A C   1 
ATOM   1358  O O   . ARG A 1 177 ? 92.252  33.842  93.587  1.00 132.58 ? 252  ARG A O   1 
ATOM   1359  C CB  . ARG A 1 177 ? 91.372  33.972  90.436  1.00 103.53 ? 252  ARG A CB  1 
ATOM   1360  C CG  . ARG A 1 177 ? 91.193  35.367  91.004  1.00 111.08 ? 252  ARG A CG  1 
ATOM   1361  C CD  . ARG A 1 177 ? 90.675  36.324  89.941  1.00 120.32 ? 252  ARG A CD  1 
ATOM   1362  N NE  . ARG A 1 177 ? 89.234  36.203  89.751  1.00 147.68 ? 252  ARG A NE  1 
ATOM   1363  C CZ  . ARG A 1 177 ? 88.392  37.228  89.736  1.00 162.41 ? 252  ARG A CZ  1 
ATOM   1364  N NH1 . ARG A 1 177 ? 88.813  38.469  89.911  1.00 157.21 ? 252  ARG A NH1 1 
ATOM   1365  N NH2 . ARG A 1 177 ? 87.095  37.003  89.537  1.00 177.80 ? 252  ARG A NH2 1 
ATOM   1366  N N   . ASN A 1 178 ? 90.511  32.481  93.147  1.00 123.90 ? 253  ASN A N   1 
ATOM   1367  C CA  . ASN A 1 178 ? 90.105  32.450  94.548  1.00 137.03 ? 253  ASN A CA  1 
ATOM   1368  C C   . ASN A 1 178 ? 91.133  31.709  95.396  1.00 145.68 ? 253  ASN A C   1 
ATOM   1369  O O   . ASN A 1 178 ? 91.392  32.092  96.543  1.00 157.21 ? 253  ASN A O   1 
ATOM   1370  C CB  . ASN A 1 178 ? 88.723  31.812  94.682  1.00 120.77 ? 253  ASN A CB  1 
ATOM   1371  C CG  . ASN A 1 178 ? 87.683  32.487  93.806  1.00 131.41 ? 253  ASN A CG  1 
ATOM   1372  O OD1 . ASN A 1 178 ? 87.688  33.708  93.647  1.00 124.43 ? 253  ASN A OD1 1 
ATOM   1373  N ND2 . ASN A 1 178 ? 86.780  31.695  93.240  1.00 145.39 ? 253  ASN A ND2 1 
ATOM   1374  N N   . LYS A 1 179 ? 91.734  30.656  94.843  1.00 135.93 ? 254  LYS A N   1 
ATOM   1375  C CA  . LYS A 1 179 ? 92.804  29.903  95.499  1.00 140.63 ? 254  LYS A CA  1 
ATOM   1376  C C   . LYS A 1 179 ? 92.416  29.426  96.897  1.00 144.36 ? 254  LYS A C   1 
ATOM   1377  O O   . LYS A 1 179 ? 93.105  29.719  97.875  1.00 152.15 ? 254  LYS A O   1 
ATOM   1378  C CB  . LYS A 1 179 ? 94.082  30.746  95.573  1.00 152.43 ? 254  LYS A CB  1 
ATOM   1379  C CG  . LYS A 1 179 ? 95.360  29.951  95.368  1.00 153.74 ? 254  LYS A CG  1 
ATOM   1380  C CD  . LYS A 1 179 ? 96.526  30.861  95.026  1.00 158.30 ? 254  LYS A CD  1 
ATOM   1381  C CE  . LYS A 1 179 ? 97.249  30.381  93.778  1.00 153.46 ? 254  LYS A CE  1 
ATOM   1382  N NZ  . LYS A 1 179 ? 97.754  28.989  93.929  1.00 162.69 ? 254  LYS A NZ  1 
ATOM   1383  N N   . ASN A 1 186 ? 99.757  29.623  90.556  1.00 128.76 ? 261  ASN A N   1 
ATOM   1384  C CA  . ASN A 1 186 ? 99.867  30.759  89.649  1.00 118.52 ? 261  ASN A CA  1 
ATOM   1385  C C   . ASN A 1 186 ? 100.071 30.289  88.215  1.00 109.91 ? 261  ASN A C   1 
ATOM   1386  O O   . ASN A 1 186 ? 99.525  30.874  87.279  1.00 111.06 ? 261  ASN A O   1 
ATOM   1387  C CB  . ASN A 1 186 ? 101.015 31.679  90.071  1.00 115.76 ? 261  ASN A CB  1 
ATOM   1388  C CG  . ASN A 1 186 ? 100.726 33.139  89.786  1.00 119.83 ? 261  ASN A CG  1 
ATOM   1389  O OD1 . ASN A 1 186 ? 101.484 33.809  89.085  1.00 138.15 ? 261  ASN A OD1 1 
ATOM   1390  N ND2 . ASN A 1 186 ? 99.618  33.637  90.322  1.00 120.47 ? 261  ASN A ND2 1 
ATOM   1391  N N   . GLU A 1 187 ? 100.864 29.230  88.044  1.00 116.08 ? 262  GLU A N   1 
ATOM   1392  C CA  . GLU A 1 187 ? 101.092 28.699  86.705  1.00 111.23 ? 262  GLU A CA  1 
ATOM   1393  C C   . GLU A 1 187 ? 99.834  28.067  86.127  1.00 108.80 ? 262  GLU A C   1 
ATOM   1394  O O   . GLU A 1 187 ? 99.609  28.143  84.913  1.00 106.43 ? 262  GLU A O   1 
ATOM   1395  C CB  . GLU A 1 187 ? 102.240 27.688  86.721  1.00 97.31  ? 262  GLU A CB  1 
ATOM   1396  C CG  . GLU A 1 187 ? 102.010 26.469  87.599  1.00 130.41 ? 262  GLU A CG  1 
ATOM   1397  C CD  . GLU A 1 187 ? 102.796 26.533  88.891  1.00 148.32 ? 262  GLU A CD  1 
ATOM   1398  O OE1 . GLU A 1 187 ? 103.369 27.602  89.183  1.00 165.84 ? 262  GLU A OE1 1 
ATOM   1399  O OE2 . GLU A 1 187 ? 102.844 25.513  89.610  1.00 153.91 ? 262  GLU A OE2 1 
ATOM   1400  N N   . ARG A 1 188 ? 98.998  27.456  86.971  1.00 102.26 ? 263  ARG A N   1 
ATOM   1401  C CA  . ARG A 1 188 ? 97.784  26.821  86.468  1.00 98.36  ? 263  ARG A CA  1 
ATOM   1402  C C   . ARG A 1 188 ? 96.798  27.856  85.941  1.00 90.86  ? 263  ARG A C   1 
ATOM   1403  O O   . ARG A 1 188 ? 96.188  27.663  84.884  1.00 102.40 ? 263  ARG A O   1 
ATOM   1404  C CB  . ARG A 1 188 ? 97.126  25.969  87.555  1.00 132.33 ? 263  ARG A CB  1 
ATOM   1405  C CG  . ARG A 1 188 ? 97.801  24.635  87.835  1.00 153.28 ? 263  ARG A CG  1 
ATOM   1406  C CD  . ARG A 1 188 ? 97.579  24.201  89.278  1.00 178.01 ? 263  ARG A CD  1 
ATOM   1407  N NE  . ARG A 1 188 ? 97.661  25.327  90.201  1.00 202.07 ? 263  ARG A NE  1 
ATOM   1408  C CZ  . ARG A 1 188 ? 98.779  25.733  90.786  1.00 201.26 ? 263  ARG A CZ  1 
ATOM   1409  N NH1 . ARG A 1 188 ? 99.926  25.104  90.594  1.00 204.62 ? 263  ARG A NH1 1 
ATOM   1410  N NH2 . ARG A 1 188 ? 98.745  26.797  91.582  1.00 184.54 ? 263  ARG A NH2 1 
ATOM   1411  N N   . LEU A 1 189 ? 96.614  28.958  86.672  1.00 79.69  ? 264  LEU A N   1 
ATOM   1412  C CA  . LEU A 1 189 ? 95.674  29.977  86.215  1.00 87.84  ? 264  LEU A CA  1 
ATOM   1413  C C   . LEU A 1 189 ? 96.182  30.681  84.964  1.00 81.10  ? 264  LEU A C   1 
ATOM   1414  O O   . LEU A 1 189 ? 95.382  31.109  84.124  1.00 92.86  ? 264  LEU A O   1 
ATOM   1415  C CB  . LEU A 1 189 ? 95.386  30.978  87.338  1.00 72.09  ? 264  LEU A CB  1 
ATOM   1416  C CG  . LEU A 1 189 ? 96.534  31.716  88.028  1.00 98.15  ? 264  LEU A CG  1 
ATOM   1417  C CD1 . LEU A 1 189 ? 96.741  33.089  87.409  1.00 103.35 ? 264  LEU A CD1 1 
ATOM   1418  C CD2 . LEU A 1 189 ? 96.264  31.831  89.521  1.00 101.20 ? 264  LEU A CD2 1 
ATOM   1419  N N   . GLU A 1 190 ? 97.500  30.780  84.801  1.00 76.78  ? 265  GLU A N   1 
ATOM   1420  C CA  . GLU A 1 190 ? 98.036  31.327  83.559  1.00 86.59  ? 265  GLU A CA  1 
ATOM   1421  C C   . GLU A 1 190 ? 97.809  30.369  82.396  1.00 85.17  ? 265  GLU A C   1 
ATOM   1422  O O   . GLU A 1 190 ? 97.449  30.797  81.289  1.00 82.90  ? 265  GLU A O   1 
ATOM   1423  C CB  . GLU A 1 190 ? 99.519  31.630  83.729  1.00 88.00  ? 265  GLU A CB  1 
ATOM   1424  C CG  . GLU A 1 190 ? 99.816  32.839  84.592  1.00 117.66 ? 265  GLU A CG  1 
ATOM   1425  C CD  . GLU A 1 190 ? 101.134 32.678  85.299  1.00 118.16 ? 265  GLU A CD  1 
ATOM   1426  O OE1 . GLU A 1 190 ? 101.920 31.830  84.837  1.00 100.90 ? 265  GLU A OE1 1 
ATOM   1427  O OE2 . GLU A 1 190 ? 101.386 33.385  86.299  1.00 133.47 ? 265  GLU A OE2 1 
ATOM   1428  N N   . LEU A 1 191 ? 98.032  29.070  82.626  1.00 79.48  ? 266  LEU A N   1 
ATOM   1429  C CA  . LEU A 1 191 ? 97.612  28.060  81.658  1.00 64.19  ? 266  LEU A CA  1 
ATOM   1430  C C   . LEU A 1 191 ? 96.156  28.255  81.268  1.00 74.95  ? 266  LEU A C   1 
ATOM   1431  O O   . LEU A 1 191 ? 95.809  28.212  80.086  1.00 79.94  ? 266  LEU A O   1 
ATOM   1432  C CB  . LEU A 1 191 ? 97.810  26.653  82.226  1.00 67.99  ? 266  LEU A CB  1 
ATOM   1433  C CG  . LEU A 1 191 ? 99.208  26.055  82.334  1.00 81.42  ? 266  LEU A CG  1 
ATOM   1434  C CD1 . LEU A 1 191 ? 99.261  25.071  83.480  1.00 97.31  ? 266  LEU A CD1 1 
ATOM   1435  C CD2 . LEU A 1 191 ? 99.557  25.353  81.034  1.00 66.42  ? 266  LEU A CD2 1 
ATOM   1436  N N   . LEU A 1 192 ? 95.290  28.463  82.262  1.00 67.26  ? 267  LEU A N   1 
ATOM   1437  C CA  . LEU A 1 192 ? 93.858  28.579  82.005  1.00 70.02  ? 267  LEU A CA  1 
ATOM   1438  C C   . LEU A 1 192 ? 93.546  29.812  81.166  1.00 72.94  ? 267  LEU A C   1 
ATOM   1439  O O   . LEU A 1 192 ? 92.710  29.761  80.254  1.00 81.41  ? 267  LEU A O   1 
ATOM   1440  C CB  . LEU A 1 192 ? 93.106  28.620  83.335  1.00 59.29  ? 267  LEU A CB  1 
ATOM   1441  C CG  . LEU A 1 192 ? 93.107  27.302  84.114  1.00 63.77  ? 267  LEU A CG  1 
ATOM   1442  C CD1 . LEU A 1 192 ? 92.741  27.534  85.571  1.00 69.73  ? 267  LEU A CD1 1 
ATOM   1443  C CD2 . LEU A 1 192 ? 92.168  26.291  83.478  1.00 87.96  ? 267  LEU A CD2 1 
ATOM   1444  N N   . LEU A 1 193 ? 94.205  30.932  81.468  1.00 61.32  ? 268  LEU A N   1 
ATOM   1445  C CA  . LEU A 1 193 ? 94.038  32.141  80.668  1.00 65.49  ? 268  LEU A CA  1 
ATOM   1446  C C   . LEU A 1 193 ? 94.455  31.902  79.218  1.00 78.17  ? 268  LEU A C   1 
ATOM   1447  O O   . LEU A 1 193 ? 93.750  32.296  78.280  1.00 77.46  ? 268  LEU A O   1 
ATOM   1448  C CB  . LEU A 1 193 ? 94.846  33.284  81.288  1.00 64.61  ? 268  LEU A CB  1 
ATOM   1449  C CG  . LEU A 1 193 ? 95.173  34.496  80.412  1.00 105.59 ? 268  LEU A CG  1 
ATOM   1450  C CD1 . LEU A 1 193 ? 93.928  35.337  80.194  1.00 106.87 ? 268  LEU A CD1 1 
ATOM   1451  C CD2 . LEU A 1 193 ? 96.294  35.331  81.019  1.00 105.23 ? 268  LEU A CD2 1 
ATOM   1452  N N   . GLN A 1 194 ? 95.602  31.246  79.015  1.00 77.52  ? 269  GLN A N   1 
ATOM   1453  C CA  . GLN A 1 194 ? 96.068  30.978  77.655  1.00 70.10  ? 269  GLN A CA  1 
ATOM   1454  C C   . GLN A 1 194 ? 95.126  30.019  76.928  1.00 69.93  ? 269  GLN A C   1 
ATOM   1455  O O   . GLN A 1 194 ? 94.895  30.155  75.717  1.00 65.67  ? 269  GLN A O   1 
ATOM   1456  C CB  . GLN A 1 194 ? 97.492  30.423  77.698  1.00 67.65  ? 269  GLN A CB  1 
ATOM   1457  C CG  . GLN A 1 194 ? 98.039  29.899  76.376  1.00 56.01  ? 269  GLN A CG  1 
ATOM   1458  C CD  . GLN A 1 194 ? 98.339  31.004  75.383  1.00 65.51  ? 269  GLN A CD  1 
ATOM   1459  O OE1 . GLN A 1 194 ? 97.857  30.987  74.251  1.00 79.85  ? 269  GLN A OE1 1 
ATOM   1460  N NE2 . GLN A 1 194 ? 99.131  31.981  75.810  1.00 72.65  ? 269  GLN A NE2 1 
ATOM   1461  N N   . LYS A 1 195 ? 94.565  29.051  77.657  1.00 64.46  ? 270  LYS A N   1 
ATOM   1462  C CA  . LYS A 1 195 ? 93.607  28.122  77.066  1.00 60.52  ? 270  LYS A CA  1 
ATOM   1463  C C   . LYS A 1 195 ? 92.350  28.856  76.624  1.00 65.96  ? 270  LYS A C   1 
ATOM   1464  O O   . LYS A 1 195 ? 91.817  28.601  75.538  1.00 64.13  ? 270  LYS A O   1 
ATOM   1465  C CB  . LYS A 1 195 ? 93.259  27.018  78.066  1.00 56.30  ? 270  LYS A CB  1 
ATOM   1466  C CG  . LYS A 1 195 ? 94.405  26.090  78.419  1.00 68.41  ? 270  LYS A CG  1 
ATOM   1467  C CD  . LYS A 1 195 ? 93.901  24.763  78.958  1.00 97.57  ? 270  LYS A CD  1 
ATOM   1468  C CE  . LYS A 1 195 ? 94.882  24.184  79.968  1.00 99.13  ? 270  LYS A CE  1 
ATOM   1469  N NZ  . LYS A 1 195 ? 94.206  23.711  81.212  1.00 97.29  ? 270  LYS A NZ  1 
ATOM   1470  N N   . ARG A 1 196 ? 91.851  29.765  77.469  1.00 64.22  ? 271  ARG A N   1 
ATOM   1471  C CA  . ARG A 1 196 ? 90.728  30.612  77.075  1.00 63.30  ? 271  ARG A CA  1 
ATOM   1472  C C   . ARG A 1 196 ? 91.062  31.431  75.833  1.00 64.60  ? 271  ARG A C   1 
ATOM   1473  O O   . ARG A 1 196 ? 90.217  31.603  74.947  1.00 70.28  ? 271  ARG A O   1 
ATOM   1474  C CB  . ARG A 1 196 ? 90.338  31.543  78.228  1.00 69.83  ? 271  ARG A CB  1 
ATOM   1475  C CG  . ARG A 1 196 ? 89.265  32.566  77.853  1.00 90.32  ? 271  ARG A CG  1 
ATOM   1476  C CD  . ARG A 1 196 ? 87.914  32.371  78.546  1.00 80.51  ? 271  ARG A CD  1 
ATOM   1477  N NE  . ARG A 1 196 ? 86.935  33.318  78.019  1.00 108.19 ? 271  ARG A NE  1 
ATOM   1478  C CZ  . ARG A 1 196 ? 85.660  33.045  77.771  1.00 109.73 ? 271  ARG A CZ  1 
ATOM   1479  N NH1 . ARG A 1 196 ? 85.095  31.928  78.195  1.00 103.54 ? 271  ARG A NH1 1 
ATOM   1480  N NH2 . ARG A 1 196 ? 84.923  33.934  77.110  1.00 114.10 ? 271  ARG A NH2 1 
ATOM   1481  N N   . LYS A 1 197 ? 92.288  31.955  75.761  1.00 68.67  ? 272  LYS A N   1 
ATOM   1482  C CA  . LYS A 1 197 ? 92.695  32.739  74.598  1.00 74.11  ? 272  LYS A CA  1 
ATOM   1483  C C   . LYS A 1 197 ? 92.622  31.911  73.318  1.00 70.49  ? 272  LYS A C   1 
ATOM   1484  O O   . LYS A 1 197 ? 92.041  32.340  72.308  1.00 72.97  ? 272  LYS A O   1 
ATOM   1485  C CB  . LYS A 1 197 ? 94.112  33.281  74.805  1.00 64.78  ? 272  LYS A CB  1 
ATOM   1486  C CG  . LYS A 1 197 ? 94.689  33.991  73.590  1.00 59.45  ? 272  LYS A CG  1 
ATOM   1487  C CD  . LYS A 1 197 ? 95.509  35.204  74.000  1.00 69.75  ? 272  LYS A CD  1 
ATOM   1488  C CE  . LYS A 1 197 ? 96.914  34.818  74.436  1.00 79.64  ? 272  LYS A CE  1 
ATOM   1489  N NZ  . LYS A 1 197 ? 97.711  34.199  73.340  1.00 91.59  ? 272  LYS A NZ  1 
ATOM   1490  N N   . GLU A 1 198 ? 93.205  30.711  73.346  1.00 62.50  ? 273  GLU A N   1 
ATOM   1491  C CA  . GLU A 1 198 ? 93.179  29.862  72.157  1.00 66.56  ? 273  GLU A CA  1 
ATOM   1492  C C   . GLU A 1 198 ? 91.765  29.394  71.828  1.00 72.10  ? 273  GLU A C   1 
ATOM   1493  O O   . GLU A 1 198 ? 91.419  29.250  70.647  1.00 77.89  ? 273  GLU A O   1 
ATOM   1494  C CB  . GLU A 1 198 ? 94.119  28.673  72.339  1.00 79.81  ? 273  GLU A CB  1 
ATOM   1495  C CG  . GLU A 1 198 ? 95.583  29.045  72.208  1.00 68.00  ? 273  GLU A CG  1 
ATOM   1496  C CD  . GLU A 1 198 ? 96.483  28.186  73.064  1.00 77.29  ? 273  GLU A CD  1 
ATOM   1497  O OE1 . GLU A 1 198 ? 95.964  27.505  73.975  1.00 82.55  ? 273  GLU A OE1 1 
ATOM   1498  O OE2 . GLU A 1 198 ? 97.711  28.193  72.826  1.00 65.55  ? 273  GLU A OE2 1 
ATOM   1499  N N   . LEU A 1 199 ? 90.932  29.164  72.847  1.00 69.99  ? 274  LEU A N   1 
ATOM   1500  C CA  . LEU A 1 199 ? 89.535  28.826  72.594  1.00 55.15  ? 274  LEU A CA  1 
ATOM   1501  C C   . LEU A 1 199 ? 88.817  29.968  71.890  1.00 54.95  ? 274  LEU A C   1 
ATOM   1502  O O   . LEU A 1 199 ? 88.000  29.740  70.991  1.00 66.32  ? 274  LEU A O   1 
ATOM   1503  C CB  . LEU A 1 199 ? 88.826  28.486  73.904  1.00 34.81  ? 274  LEU A CB  1 
ATOM   1504  C CG  . LEU A 1 199 ? 88.859  27.038  74.386  1.00 43.52  ? 274  LEU A CG  1 
ATOM   1505  C CD1 . LEU A 1 199 ? 88.480  26.971  75.857  1.00 48.61  ? 274  LEU A CD1 1 
ATOM   1506  C CD2 . LEU A 1 199 ? 87.939  26.173  73.549  1.00 42.20  ? 274  LEU A CD2 1 
ATOM   1507  N N   . GLN A 1 200 ? 89.107  31.208  72.291  1.00 54.06  ? 275  GLN A N   1 
ATOM   1508  C CA  . GLN A 1 200 ? 88.499  32.359  71.630  1.00 62.59  ? 275  GLN A CA  1 
ATOM   1509  C C   . GLN A 1 200 ? 88.967  32.471  70.184  1.00 78.77  ? 275  GLN A C   1 
ATOM   1510  O O   . GLN A 1 200 ? 88.186  32.837  69.296  1.00 85.78  ? 275  GLN A O   1 
ATOM   1511  C CB  . GLN A 1 200 ? 88.820  33.642  72.397  1.00 55.74  ? 275  GLN A CB  1 
ATOM   1512  C CG  . GLN A 1 200 ? 88.073  34.866  71.887  1.00 51.58  ? 275  GLN A CG  1 
ATOM   1513  C CD  . GLN A 1 200 ? 86.583  34.628  71.746  1.00 86.96  ? 275  GLN A CD  1 
ATOM   1514  O OE1 . GLN A 1 200 ? 85.868  34.506  72.742  1.00 103.24 ? 275  GLN A OE1 1 
ATOM   1515  N NE2 . GLN A 1 200 ? 86.107  34.557  70.508  1.00 91.99  ? 275  GLN A NE2 1 
ATOM   1516  N N   . GLU A 1 201 ? 90.242  32.169  69.928  1.00 63.73  ? 276  GLU A N   1 
ATOM   1517  C CA  . GLU A 1 201 ? 90.714  32.155  68.544  1.00 63.03  ? 276  GLU A CA  1 
ATOM   1518  C C   . GLU A 1 201 ? 89.974  31.102  67.720  1.00 68.32  ? 276  GLU A C   1 
ATOM   1519  O O   . GLU A 1 201 ? 89.560  31.365  66.580  1.00 78.20  ? 276  GLU A O   1 
ATOM   1520  C CB  . GLU A 1 201 ? 92.224  31.921  68.498  1.00 80.44  ? 276  GLU A CB  1 
ATOM   1521  C CG  . GLU A 1 201 ? 93.044  32.979  69.225  1.00 91.27  ? 276  GLU A CG  1 
ATOM   1522  C CD  . GLU A 1 201 ? 94.456  32.515  69.530  1.00 76.52  ? 276  GLU A CD  1 
ATOM   1523  O OE1 . GLU A 1 201 ? 94.767  31.338  69.254  1.00 72.87  ? 276  GLU A OE1 1 
ATOM   1524  O OE2 . GLU A 1 201 ? 95.256  33.333  70.034  1.00 59.64  ? 276  GLU A OE2 1 
ATOM   1525  N N   . ASN A 1 202 ? 89.793  29.904  68.285  1.00 61.18  ? 277  ASN A N   1 
ATOM   1526  C CA  . ASN A 1 202 ? 89.019  28.870  67.598  1.00 75.51  ? 277  ASN A CA  1 
ATOM   1527  C C   . ASN A 1 202 ? 87.591  29.334  67.329  1.00 75.56  ? 277  ASN A C   1 
ATOM   1528  O O   . ASN A 1 202 ? 87.030  29.063  66.258  1.00 70.67  ? 277  ASN A O   1 
ATOM   1529  C CB  . ASN A 1 202 ? 89.004  27.579  68.418  1.00 61.78  ? 277  ASN A CB  1 
ATOM   1530  C CG  . ASN A 1 202 ? 90.384  26.988  68.606  1.00 62.25  ? 277  ASN A CG  1 
ATOM   1531  O OD1 . ASN A 1 202 ? 91.157  26.868  67.656  1.00 77.15  ? 277  ASN A OD1 1 
ATOM   1532  N ND2 . ASN A 1 202 ? 90.698  26.603  69.838  1.00 82.51  ? 277  ASN A ND2 1 
ATOM   1533  N N   . GLN A 1 203 ? 86.980  30.020  68.301  1.00 59.03  ? 278  GLN A N   1 
ATOM   1534  C CA  . GLN A 1 203 ? 85.610  30.481  68.116  1.00 65.66  ? 278  GLN A CA  1 
ATOM   1535  C C   . GLN A 1 203 ? 85.537  31.526  67.015  1.00 68.02  ? 278  GLN A C   1 
ATOM   1536  O O   . GLN A 1 203 ? 84.574  31.554  66.243  1.00 76.72  ? 278  GLN A O   1 
ATOM   1537  C CB  . GLN A 1 203 ? 85.041  31.050  69.415  1.00 75.06  ? 278  GLN A CB  1 
ATOM   1538  C CG  . GLN A 1 203 ? 83.519  30.927  69.495  1.00 99.31  ? 278  GLN A CG  1 
ATOM   1539  C CD  . GLN A 1 203 ? 82.918  31.614  70.710  1.00 109.07 ? 278  GLN A CD  1 
ATOM   1540  O OE1 . GLN A 1 203 ? 83.604  31.881  71.695  1.00 99.70  ? 278  GLN A OE1 1 
ATOM   1541  N NE2 . GLN A 1 203 ? 81.614  31.867  70.657  1.00 111.47 ? 278  GLN A NE2 1 
ATOM   1542  N N   . ASP A 1 204 ? 86.550  32.392  66.924  1.00 59.32  ? 279  ASP A N   1 
ATOM   1543  C CA  . ASP A 1 204 ? 86.581  33.370  65.840  1.00 68.63  ? 279  ASP A CA  1 
ATOM   1544  C C   . ASP A 1 204 ? 86.733  32.690  64.486  1.00 63.60  ? 279  ASP A C   1 
ATOM   1545  O O   . ASP A 1 204 ? 86.130  33.123  63.498  1.00 72.38  ? 279  ASP A O   1 
ATOM   1546  C CB  . ASP A 1 204 ? 87.706  34.382  66.057  1.00 64.35  ? 279  ASP A CB  1 
ATOM   1547  C CG  . ASP A 1 204 ? 87.590  35.114  67.379  1.00 76.62  ? 279  ASP A CG  1 
ATOM   1548  O OD1 . ASP A 1 204 ? 86.449  35.367  67.821  1.00 82.60  ? 279  ASP A OD1 1 
ATOM   1549  O OD2 . ASP A 1 204 ? 88.640  35.445  67.971  1.00 86.20  ? 279  ASP A OD2 1 
ATOM   1550  N N   . GLU A 1 205 ? 87.528  31.623  64.419  1.00 58.95  ? 280  GLU A N   1 
ATOM   1551  C CA  . GLU A 1 205 ? 87.688  30.909  63.152  1.00 66.34  ? 280  GLU A CA  1 
ATOM   1552  C C   . GLU A 1 205 ? 86.370  30.260  62.723  1.00 67.82  ? 280  GLU A C   1 
ATOM   1553  O O   . GLU A 1 205 ? 85.936  30.389  61.563  1.00 71.67  ? 280  GLU A O   1 
ATOM   1554  C CB  . GLU A 1 205 ? 88.799  29.866  63.295  1.00 76.28  ? 280  GLU A CB  1 
ATOM   1555  C CG  . GLU A 1 205 ? 89.485  29.455  61.998  1.00 107.42 ? 280  GLU A CG  1 
ATOM   1556  C CD  . GLU A 1 205 ? 89.747  30.627  61.073  1.00 111.32 ? 280  GLU A CD  1 
ATOM   1557  O OE1 . GLU A 1 205 ? 90.624  31.453  61.403  1.00 89.84  ? 280  GLU A OE1 1 
ATOM   1558  O OE2 . GLU A 1 205 ? 89.094  30.720  60.011  1.00 111.24 ? 280  GLU A OE2 1 
ATOM   1559  N N   . ILE A 1 206 ? 85.715  29.564  63.656  1.00 64.47  ? 281  ILE A N   1 
ATOM   1560  C CA  . ILE A 1 206 ? 84.410  28.971  63.369  1.00 56.56  ? 281  ILE A CA  1 
ATOM   1561  C C   . ILE A 1 206 ? 83.402  30.053  62.997  1.00 70.79  ? 281  ILE A C   1 
ATOM   1562  O O   . ILE A 1 206 ? 82.526  29.842  62.148  1.00 79.52  ? 281  ILE A O   1 
ATOM   1563  C CB  . ILE A 1 206 ? 83.925  28.129  64.566  1.00 48.84  ? 281  ILE A CB  1 
ATOM   1564  C CG1 . ILE A 1 206 ? 84.946  27.041  64.908  1.00 63.81  ? 281  ILE A CG1 1 
ATOM   1565  C CG2 . ILE A 1 206 ? 82.572  27.499  64.273  1.00 58.62  ? 281  ILE A CG2 1 
ATOM   1566  C CD1 . ILE A 1 206 ? 85.331  26.178  63.731  1.00 59.51  ? 281  ILE A CD1 1 
ATOM   1567  N N   . GLU A 1 207 ? 83.515  31.231  63.617  1.00 67.21  ? 282  GLU A N   1 
ATOM   1568  C CA  . GLU A 1 207 ? 82.617  32.336  63.299  1.00 60.34  ? 282  GLU A CA  1 
ATOM   1569  C C   . GLU A 1 207 ? 82.842  32.837  61.881  1.00 67.47  ? 282  GLU A C   1 
ATOM   1570  O O   . GLU A 1 207 ? 81.884  33.175  61.182  1.00 74.44  ? 282  GLU A O   1 
ATOM   1571  C CB  . GLU A 1 207 ? 82.807  33.469  64.310  1.00 64.08  ? 282  GLU A CB  1 
ATOM   1572  C CG  . GLU A 1 207 ? 82.096  34.765  63.955  1.00 89.28  ? 282  GLU A CG  1 
ATOM   1573  C CD  . GLU A 1 207 ? 80.598  34.584  63.788  1.00 119.79 ? 282  GLU A CD  1 
ATOM   1574  O OE1 . GLU A 1 207 ? 79.944  34.129  64.750  1.00 107.92 ? 282  GLU A OE1 1 
ATOM   1575  O OE2 . GLU A 1 207 ? 80.071  34.900  62.699  1.00 141.05 ? 282  GLU A OE2 1 
ATOM   1576  N N   . ASN A 1 208 ? 84.102  32.904  61.443  1.00 77.95  ? 283  ASN A N   1 
ATOM   1577  C CA  . ASN A 1 208 ? 84.380  33.250  60.051  1.00 77.85  ? 283  ASN A CA  1 
ATOM   1578  C C   . ASN A 1 208 ? 83.714  32.259  59.108  1.00 77.83  ? 283  ASN A C   1 
ATOM   1579  O O   . ASN A 1 208 ? 83.064  32.652  58.132  1.00 77.68  ? 283  ASN A O   1 
ATOM   1580  C CB  . ASN A 1 208 ? 85.887  33.297  59.792  1.00 84.00  ? 283  ASN A CB  1 
ATOM   1581  C CG  . ASN A 1 208 ? 86.611  34.249  60.717  1.00 120.32 ? 283  ASN A CG  1 
ATOM   1582  O OD1 . ASN A 1 208 ? 86.075  35.289  61.098  1.00 134.33 ? 283  ASN A OD1 1 
ATOM   1583  N ND2 . ASN A 1 208 ? 87.843  33.904  61.077  1.00 137.52 ? 283  ASN A ND2 1 
ATOM   1584  N N   . MET A 1 209 ? 83.858  30.963  59.393  1.00 73.64  ? 284  MET A N   1 
ATOM   1585  C CA  . MET A 1 209 ? 83.243  29.947  58.536  1.00 70.39  ? 284  MET A CA  1 
ATOM   1586  C C   . MET A 1 209 ? 81.722  30.100  58.489  1.00 67.96  ? 284  MET A C   1 
ATOM   1587  O O   . MET A 1 209 ? 81.112  30.090  57.408  1.00 64.70  ? 284  MET A O   1 
ATOM   1588  C CB  . MET A 1 209 ? 83.631  28.556  59.032  1.00 69.24  ? 284  MET A CB  1 
ATOM   1589  C CG  . MET A 1 209 ? 85.126  28.327  59.076  1.00 60.88  ? 284  MET A CG  1 
ATOM   1590  S SD  . MET A 1 209 ? 85.554  26.902  60.082  1.00 73.28  ? 284  MET A SD  1 
ATOM   1591  C CE  . MET A 1 209 ? 87.300  27.191  60.334  1.00 79.59  ? 284  MET A CE  1 
ATOM   1592  N N   . MET A 1 210 ? 81.096  30.237  59.661  1.00 63.41  ? 285  MET A N   1 
ATOM   1593  C CA  . MET A 1 210 ? 79.642  30.352  59.741  1.00 61.03  ? 285  MET A CA  1 
ATOM   1594  C C   . MET A 1 210 ? 79.143  31.613  59.047  1.00 68.24  ? 285  MET A C   1 
ATOM   1595  O O   . MET A 1 210 ? 78.135  31.581  58.330  1.00 63.75  ? 285  MET A O   1 
ATOM   1596  C CB  . MET A 1 210 ? 79.213  30.344  61.206  1.00 53.80  ? 285  MET A CB  1 
ATOM   1597  C CG  . MET A 1 210 ? 79.374  28.999  61.886  1.00 52.00  ? 285  MET A CG  1 
ATOM   1598  S SD  . MET A 1 210 ? 78.559  28.956  63.490  1.00 67.83  ? 285  MET A SD  1 
ATOM   1599  C CE  . MET A 1 210 ? 78.685  30.677  63.978  1.00 55.98  ? 285  MET A CE  1 
ATOM   1600  N N   . ASN A 1 211 ? 79.830  32.737  59.267  1.00 64.10  ? 286  ASN A N   1 
ATOM   1601  C CA  . ASN A 1 211 ? 79.492  33.986  58.595  1.00 68.20  ? 286  ASN A CA  1 
ATOM   1602  C C   . ASN A 1 211 ? 79.605  33.840  57.086  1.00 64.63  ? 286  ASN A C   1 
ATOM   1603  O O   . ASN A 1 211 ? 78.769  34.360  56.338  1.00 68.73  ? 286  ASN A O   1 
ATOM   1604  C CB  . ASN A 1 211 ? 80.415  35.097  59.094  1.00 63.87  ? 286  ASN A CB  1 
ATOM   1605  C CG  . ASN A 1 211 ? 79.737  36.445  59.143  1.00 87.99  ? 286  ASN A CG  1 
ATOM   1606  O OD1 . ASN A 1 211 ? 78.618  36.576  59.637  1.00 109.08 ? 286  ASN A OD1 1 
ATOM   1607  N ND2 . ASN A 1 211 ? 80.420  37.466  58.636  1.00 101.87 ? 286  ASN A ND2 1 
ATOM   1608  N N   . ALA A 1 212 ? 80.640  33.138  56.620  1.00 62.14  ? 287  ALA A N   1 
ATOM   1609  C CA  . ALA A 1 212 ? 80.795  32.914  55.189  1.00 68.11  ? 287  ALA A CA  1 
ATOM   1610  C C   . ALA A 1 212 ? 79.603  32.151  54.630  1.00 64.10  ? 287  ALA A C   1 
ATOM   1611  O O   . ALA A 1 212 ? 79.023  32.545  53.611  1.00 64.43  ? 287  ALA A O   1 
ATOM   1612  C CB  . ALA A 1 212 ? 82.100  32.165  54.915  1.00 64.55  ? 287  ALA A CB  1 
ATOM   1613  N N   . ILE A 1 213 ? 79.209  31.062  55.296  1.00 69.23  ? 288  ILE A N   1 
ATOM   1614  C CA  . ILE A 1 213 ? 78.070  30.283  54.802  1.00 63.73  ? 288  ILE A CA  1 
ATOM   1615  C C   . ILE A 1 213 ? 76.798  31.125  54.813  1.00 59.99  ? 288  ILE A C   1 
ATOM   1616  O O   . ILE A 1 213 ? 76.036  31.141  53.838  1.00 51.95  ? 288  ILE A O   1 
ATOM   1617  C CB  . ILE A 1 213 ? 77.893  28.986  55.611  1.00 51.96  ? 288  ILE A CB  1 
ATOM   1618  C CG1 . ILE A 1 213 ? 79.099  28.071  55.422  1.00 58.12  ? 288  ILE A CG1 1 
ATOM   1619  C CG2 . ILE A 1 213 ? 76.620  28.267  55.190  1.00 47.27  ? 288  ILE A CG2 1 
ATOM   1620  C CD1 . ILE A 1 213 ? 79.130  26.920  56.392  1.00 62.25  ? 288  ILE A CD1 1 
ATOM   1621  N N   . PHE A 1 214 ? 76.552  31.843  55.912  1.00 56.24  ? 289  PHE A N   1 
ATOM   1622  C CA  . PHE A 1 214 ? 75.309  32.600  56.033  1.00 59.93  ? 289  PHE A CA  1 
ATOM   1623  C C   . PHE A 1 214 ? 75.229  33.711  54.992  1.00 61.64  ? 289  PHE A C   1 
ATOM   1624  O O   . PHE A 1 214 ? 74.255  33.797  54.234  1.00 62.48  ? 289  PHE A O   1 
ATOM   1625  C CB  . PHE A 1 214 ? 75.178  33.176  57.444  1.00 50.18  ? 289  PHE A CB  1 
ATOM   1626  C CG  . PHE A 1 214 ? 73.793  33.660  57.773  1.00 60.82  ? 289  PHE A CG  1 
ATOM   1627  C CD1 . PHE A 1 214 ? 72.822  32.777  58.215  1.00 49.51  ? 289  PHE A CD1 1 
ATOM   1628  C CD2 . PHE A 1 214 ? 73.460  34.997  57.629  1.00 69.38  ? 289  PHE A CD2 1 
ATOM   1629  C CE1 . PHE A 1 214 ? 71.548  33.220  58.513  1.00 58.94  ? 289  PHE A CE1 1 
ATOM   1630  C CE2 . PHE A 1 214 ? 72.186  35.447  57.925  1.00 58.68  ? 289  PHE A CE2 1 
ATOM   1631  C CZ  . PHE A 1 214 ? 71.229  34.557  58.367  1.00 54.82  ? 289  PHE A CZ  1 
ATOM   1632  N N   . LYS A 1 215 ? 76.249  34.571  54.939  1.00 56.44  ? 290  LYS A N   1 
ATOM   1633  C CA  . LYS A 1 215 ? 76.210  35.735  54.065  1.00 58.17  ? 290  LYS A CA  1 
ATOM   1634  C C   . LYS A 1 215 ? 76.418  35.379  52.599  1.00 58.92  ? 290  LYS A C   1 
ATOM   1635  O O   . LYS A 1 215 ? 76.005  36.150  51.727  1.00 60.31  ? 290  LYS A O   1 
ATOM   1636  C CB  . LYS A 1 215 ? 77.275  36.742  54.500  1.00 62.45  ? 290  LYS A CB  1 
ATOM   1637  C CG  . LYS A 1 215 ? 76.937  37.521  55.761  1.00 82.37  ? 290  LYS A CG  1 
ATOM   1638  C CD  . LYS A 1 215 ? 76.138  38.781  55.463  1.00 108.47 ? 290  LYS A CD  1 
ATOM   1639  C CE  . LYS A 1 215 ? 75.430  39.278  56.714  1.00 118.94 ? 290  LYS A CE  1 
ATOM   1640  N NZ  . LYS A 1 215 ? 74.406  40.315  56.414  1.00 120.43 ? 290  LYS A NZ  1 
ATOM   1641  N N   . GLY A 1 216 ? 77.047  34.242  52.300  1.00 52.64  ? 291  GLY A N   1 
ATOM   1642  C CA  . GLY A 1 216 ? 77.315  33.900  50.918  1.00 46.24  ? 291  GLY A CA  1 
ATOM   1643  C C   . GLY A 1 216 ? 76.344  32.895  50.342  1.00 58.62  ? 291  GLY A C   1 
ATOM   1644  O O   . GLY A 1 216 ? 76.224  32.776  49.118  1.00 58.37  ? 291  GLY A O   1 
ATOM   1645  N N   . VAL A 1 217 ? 75.640  32.164  51.200  1.00 62.87  ? 292  VAL A N   1 
ATOM   1646  C CA  . VAL A 1 217 ? 74.712  31.160  50.700  1.00 58.88  ? 292  VAL A CA  1 
ATOM   1647  C C   . VAL A 1 217 ? 73.297  31.439  51.185  1.00 60.42  ? 292  VAL A C   1 
ATOM   1648  O O   . VAL A 1 217 ? 72.367  31.527  50.373  1.00 69.34  ? 292  VAL A O   1 
ATOM   1649  C CB  . VAL A 1 217 ? 75.147  29.741  51.100  1.00 52.26  ? 292  VAL A CB  1 
ATOM   1650  C CG1 . VAL A 1 217 ? 74.118  28.736  50.627  1.00 58.21  ? 292  VAL A CG1 1 
ATOM   1651  C CG2 . VAL A 1 217 ? 76.511  29.419  50.515  1.00 44.65  ? 292  VAL A CG2 1 
ATOM   1652  N N   . PHE A 1 218 ? 73.115  31.571  52.505  1.00 52.38  ? 293  PHE A N   1 
ATOM   1653  C CA  . PHE A 1 218 ? 71.760  31.642  53.053  1.00 57.12  ? 293  PHE A CA  1 
ATOM   1654  C C   . PHE A 1 218 ? 70.995  32.843  52.514  1.00 66.74  ? 293  PHE A C   1 
ATOM   1655  O O   . PHE A 1 218 ? 69.877  32.700  52.008  1.00 68.22  ? 293  PHE A O   1 
ATOM   1656  C CB  . PHE A 1 218 ? 71.782  31.683  54.581  1.00 53.27  ? 293  PHE A CB  1 
ATOM   1657  C CG  . PHE A 1 218 ? 70.407  31.777  55.188  1.00 52.03  ? 293  PHE A CG  1 
ATOM   1658  C CD1 . PHE A 1 218 ? 69.652  30.635  55.395  1.00 56.82  ? 293  PHE A CD1 1 
ATOM   1659  C CD2 . PHE A 1 218 ? 69.848  33.008  55.504  1.00 52.96  ? 293  PHE A CD2 1 
ATOM   1660  C CE1 . PHE A 1 218 ? 68.376  30.716  55.933  1.00 65.76  ? 293  PHE A CE1 1 
ATOM   1661  C CE2 . PHE A 1 218 ? 68.568  33.095  56.041  1.00 55.18  ? 293  PHE A CE2 1 
ATOM   1662  C CZ  . PHE A 1 218 ? 67.831  31.948  56.245  1.00 57.32  ? 293  PHE A CZ  1 
ATOM   1663  N N   . VAL A 1 219 ? 71.568  34.042  52.633  1.00 66.21  ? 294  VAL A N   1 
ATOM   1664  C CA  . VAL A 1 219 ? 70.858  35.252  52.235  1.00 63.83  ? 294  VAL A CA  1 
ATOM   1665  C C   . VAL A 1 219 ? 70.519  35.268  50.753  1.00 66.20  ? 294  VAL A C   1 
ATOM   1666  O O   . VAL A 1 219 ? 69.696  36.081  50.323  1.00 63.38  ? 294  VAL A O   1 
ATOM   1667  C CB  . VAL A 1 219 ? 71.673  36.512  52.605  1.00 60.64  ? 294  VAL A CB  1 
ATOM   1668  C CG1 . VAL A 1 219 ? 72.025  36.507  54.087  1.00 55.33  ? 294  VAL A CG1 1 
ATOM   1669  C CG2 . VAL A 1 219 ? 72.924  36.615  51.750  1.00 77.99  ? 294  VAL A CG2 1 
ATOM   1670  N N   . HIS A 1 220 ? 71.128  34.384  49.964  1.00 59.00  ? 295  HIS A N   1 
ATOM   1671  C CA  . HIS A 1 220 ? 70.813  34.252  48.549  1.00 68.55  ? 295  HIS A CA  1 
ATOM   1672  C C   . HIS A 1 220 ? 69.879  33.089  48.255  1.00 68.47  ? 295  HIS A C   1 
ATOM   1673  O O   . HIS A 1 220 ? 69.097  33.165  47.301  1.00 75.28  ? 295  HIS A O   1 
ATOM   1674  C CB  . HIS A 1 220 ? 72.099  34.076  47.736  1.00 70.57  ? 295  HIS A CB  1 
ATOM   1675  C CG  . HIS A 1 220 ? 73.074  35.199  47.902  1.00 73.49  ? 295  HIS A CG  1 
ATOM   1676  N ND1 . HIS A 1 220 ? 74.322  35.022  48.457  1.00 87.97  ? 295  HIS A ND1 1 
ATOM   1677  C CD2 . HIS A 1 220 ? 72.988  36.513  47.584  1.00 72.53  ? 295  HIS A CD2 1 
ATOM   1678  C CE1 . HIS A 1 220 ? 74.961  36.178  48.481  1.00 83.70  ? 295  HIS A CE1 1 
ATOM   1679  N NE2 . HIS A 1 220 ? 74.174  37.099  47.956  1.00 71.93  ? 295  HIS A NE2 1 
ATOM   1680  N N   . ARG A 1 221 ? 69.938  32.015  49.046  1.00 62.38  ? 296  ARG A N   1 
ATOM   1681  C CA  . ARG A 1 221 ? 69.127  30.833  48.785  1.00 61.47  ? 296  ARG A CA  1 
ATOM   1682  C C   . ARG A 1 221 ? 67.829  30.788  49.582  1.00 63.48  ? 296  ARG A C   1 
ATOM   1683  O O   . ARG A 1 221 ? 66.928  30.030  49.212  1.00 62.99  ? 296  ARG A O   1 
ATOM   1684  C CB  . ARG A 1 221 ? 69.939  29.560  49.065  1.00 64.53  ? 296  ARG A CB  1 
ATOM   1685  C CG  . ARG A 1 221 ? 71.174  29.385  48.191  1.00 59.64  ? 296  ARG A CG  1 
ATOM   1686  C CD  . ARG A 1 221 ? 70.814  29.354  46.712  1.00 55.14  ? 296  ARG A CD  1 
ATOM   1687  N NE  . ARG A 1 221 ? 71.407  30.472  45.988  1.00 64.46  ? 296  ARG A NE  1 
ATOM   1688  C CZ  . ARG A 1 221 ? 70.775  31.211  45.086  1.00 78.48  ? 296  ARG A CZ  1 
ATOM   1689  N NH1 . ARG A 1 221 ? 69.508  30.993  44.776  1.00 78.88  ? 296  ARG A NH1 1 
ATOM   1690  N NH2 . ARG A 1 221 ? 71.434  32.193  44.478  1.00 87.33  ? 296  ARG A NH2 1 
ATOM   1691  N N   . TYR A 1 222 ? 67.707  31.566  50.661  1.00 63.76  ? 297  TYR A N   1 
ATOM   1692  C CA  . TYR A 1 222 ? 66.425  31.658  51.351  1.00 60.80  ? 297  TYR A CA  1 
ATOM   1693  C C   . TYR A 1 222 ? 65.373  32.342  50.489  1.00 64.52  ? 297  TYR A C   1 
ATOM   1694  O O   . TYR A 1 222 ? 64.174  32.193  50.750  1.00 64.49  ? 297  TYR A O   1 
ATOM   1695  C CB  . TYR A 1 222 ? 66.580  32.409  52.677  1.00 61.48  ? 297  TYR A CB  1 
ATOM   1696  C CG  . TYR A 1 222 ? 66.286  33.891  52.582  1.00 60.67  ? 297  TYR A CG  1 
ATOM   1697  C CD1 . TYR A 1 222 ? 67.243  34.781  52.115  1.00 64.66  ? 297  TYR A CD1 1 
ATOM   1698  C CD2 . TYR A 1 222 ? 65.053  34.401  52.971  1.00 66.28  ? 297  TYR A CD2 1 
ATOM   1699  C CE1 . TYR A 1 222 ? 66.978  36.135  52.027  1.00 65.12  ? 297  TYR A CE1 1 
ATOM   1700  C CE2 . TYR A 1 222 ? 64.781  35.750  52.886  1.00 72.09  ? 297  TYR A CE2 1 
ATOM   1701  C CZ  . TYR A 1 222 ? 65.746  36.613  52.415  1.00 65.38  ? 297  TYR A CZ  1 
ATOM   1702  O OH  . TYR A 1 222 ? 65.474  37.958  52.333  1.00 79.30  ? 297  TYR A OH  1 
ATOM   1703  N N   . ARG A 1 223 ? 65.805  33.102  49.485  1.00 63.95  ? 298  ARG A N   1 
ATOM   1704  C CA  . ARG A 1 223 ? 64.930  33.748  48.517  1.00 58.93  ? 298  ARG A CA  1 
ATOM   1705  C C   . ARG A 1 223 ? 65.108  33.147  47.125  1.00 64.49  ? 298  ARG A C   1 
ATOM   1706  O O   . ARG A 1 223 ? 64.920  33.828  46.114  1.00 68.95  ? 298  ARG A O   1 
ATOM   1707  C CB  . ARG A 1 223 ? 65.191  35.253  48.512  1.00 58.32  ? 298  ARG A CB  1 
ATOM   1708  C CG  . ARG A 1 223 ? 66.655  35.598  48.324  1.00 77.20  ? 298  ARG A CG  1 
ATOM   1709  C CD  . ARG A 1 223 ? 66.952  37.069  48.564  1.00 84.12  ? 298  ARG A CD  1 
ATOM   1710  N NE  . ARG A 1 223 ? 66.259  37.962  47.647  1.00 76.62  ? 298  ARG A NE  1 
ATOM   1711  C CZ  . ARG A 1 223 ? 66.444  39.274  47.614  1.00 84.65  ? 298  ARG A CZ  1 
ATOM   1712  N NH1 . ARG A 1 223 ? 67.292  39.872  48.434  1.00 85.97  ? 298  ARG A NH1 1 
ATOM   1713  N NH2 . ARG A 1 223 ? 65.761  40.005  46.737  1.00 90.73  ? 298  ARG A NH2 1 
ATOM   1714  N N   . ASP A 1 224 ? 65.478  31.869  47.073  1.00 67.21  ? 299  ASP A N   1 
ATOM   1715  C CA  . ASP A 1 224 ? 65.678  31.181  45.806  1.00 63.62  ? 299  ASP A CA  1 
ATOM   1716  C C   . ASP A 1 224 ? 64.367  31.076  45.036  1.00 68.60  ? 299  ASP A C   1 
ATOM   1717  O O   . ASP A 1 224 ? 63.277  31.083  45.612  1.00 69.81  ? 299  ASP A O   1 
ATOM   1718  C CB  . ASP A 1 224 ? 66.253  29.783  46.047  1.00 57.16  ? 299  ASP A CB  1 
ATOM   1719  C CG  . ASP A 1 224 ? 66.834  29.169  44.790  1.00 68.46  ? 299  ASP A CG  1 
ATOM   1720  O OD1 . ASP A 1 224 ? 66.053  28.675  43.950  1.00 63.89  ? 299  ASP A OD1 1 
ATOM   1721  O OD2 . ASP A 1 224 ? 68.073  29.176  44.643  1.00 81.30  ? 299  ASP A OD2 1 
ATOM   1722  N N   . ALA A 1 225 ? 64.482  30.973  43.710  1.00 69.18  ? 300  ALA A N   1 
ATOM   1723  C CA  . ALA A 1 225 ? 63.291  30.790  42.888  1.00 66.67  ? 300  ALA A CA  1 
ATOM   1724  C C   . ALA A 1 225 ? 62.606  29.465  43.200  1.00 59.78  ? 300  ALA A C   1 
ATOM   1725  O O   . ALA A 1 225 ? 61.372  29.387  43.236  1.00 68.17  ? 300  ALA A O   1 
ATOM   1726  C CB  . ALA A 1 225 ? 63.655  30.874  41.406  1.00 68.88  ? 300  ALA A CB  1 
ATOM   1727  N N   . ILE A 1 226 ? 63.389  28.419  43.441  1.00 54.27  ? 301  ILE A N   1 
ATOM   1728  C CA  . ILE A 1 226 ? 62.842  27.100  43.740  1.00 50.77  ? 301  ILE A CA  1 
ATOM   1729  C C   . ILE A 1 226 ? 62.365  27.076  45.187  1.00 64.65  ? 301  ILE A C   1 
ATOM   1730  O O   . ILE A 1 226 ? 63.082  27.506  46.099  1.00 73.23  ? 301  ILE A O   1 
ATOM   1731  C CB  . ILE A 1 226 ? 63.888  26.004  43.479  1.00 51.22  ? 301  ILE A CB  1 
ATOM   1732  C CG1 . ILE A 1 226 ? 64.407  26.087  42.040  1.00 56.52  ? 301  ILE A CG1 1 
ATOM   1733  C CG2 . ILE A 1 226 ? 63.303  24.628  43.755  1.00 65.25  ? 301  ILE A CG2 1 
ATOM   1734  C CD1 . ILE A 1 226 ? 63.325  26.311  41.003  1.00 67.51  ? 301  ILE A CD1 1 
ATOM   1735  N N   . ALA A 1 227 ? 61.147  26.573  45.401  1.00 66.06  ? 302  ALA A N   1 
ATOM   1736  C CA  . ALA A 1 227 ? 60.583  26.551  46.747  1.00 64.84  ? 302  ALA A CA  1 
ATOM   1737  C C   . ALA A 1 227 ? 61.313  25.557  47.644  1.00 65.90  ? 302  ALA A C   1 
ATOM   1738  O O   . ALA A 1 227 ? 61.441  25.783  48.853  1.00 72.26  ? 302  ALA A O   1 
ATOM   1739  C CB  . ALA A 1 227 ? 59.090  26.225  46.682  1.00 74.83  ? 302  ALA A CB  1 
ATOM   1740  N N   . GLU A 1 228 ? 61.794  24.451  47.067  1.00 70.63  ? 303  GLU A N   1 
ATOM   1741  C CA  . GLU A 1 228 ? 62.495  23.430  47.844  1.00 70.66  ? 303  GLU A CA  1 
ATOM   1742  C C   . GLU A 1 228 ? 63.728  24.008  48.529  1.00 70.48  ? 303  GLU A C   1 
ATOM   1743  O O   . GLU A 1 228 ? 63.973  23.762  49.719  1.00 74.38  ? 303  GLU A O   1 
ATOM   1744  C CB  . GLU A 1 228 ? 62.882  22.268  46.926  1.00 65.42  ? 303  GLU A CB  1 
ATOM   1745  C CG  . GLU A 1 228 ? 63.597  21.117  47.610  1.00 62.97  ? 303  GLU A CG  1 
ATOM   1746  C CD  . GLU A 1 228 ? 63.240  19.774  47.002  1.00 73.22  ? 303  GLU A CD  1 
ATOM   1747  O OE1 . GLU A 1 228 ? 63.082  18.796  47.761  1.00 89.64  ? 303  GLU A OE1 1 
ATOM   1748  O OE2 . GLU A 1 228 ? 63.107  19.702  45.763  1.00 84.17  ? 303  GLU A OE2 1 
ATOM   1749  N N   . ILE A 1 229 ? 64.520  24.778  47.781  1.00 55.29  ? 304  ILE A N   1 
ATOM   1750  C CA  . ILE A 1 229 ? 65.728  25.392  48.323  1.00 60.35  ? 304  ILE A CA  1 
ATOM   1751  C C   . ILE A 1 229 ? 65.377  26.333  49.471  1.00 60.35  ? 304  ILE A C   1 
ATOM   1752  O O   . ILE A 1 229 ? 66.026  26.326  50.530  1.00 71.89  ? 304  ILE A O   1 
ATOM   1753  C CB  . ILE A 1 229 ? 66.483  26.118  47.195  1.00 60.66  ? 304  ILE A CB  1 
ATOM   1754  C CG1 . ILE A 1 229 ? 66.624  25.196  45.979  1.00 61.85  ? 304  ILE A CG1 1 
ATOM   1755  C CG2 . ILE A 1 229 ? 67.841  26.589  47.669  1.00 62.36  ? 304  ILE A CG2 1 
ATOM   1756  C CD1 . ILE A 1 229 ? 67.759  25.566  45.045  1.00 50.07  ? 304  ILE A CD1 1 
ATOM   1757  N N   . ARG A 1 230 ? 64.340  27.154  49.279  1.00 51.18  ? 305  ARG A N   1 
ATOM   1758  C CA  . ARG A 1 230 ? 63.914  28.075  50.328  1.00 64.91  ? 305  ARG A CA  1 
ATOM   1759  C C   . ARG A 1 230 ? 63.501  27.323  51.584  1.00 58.95  ? 305  ARG A C   1 
ATOM   1760  O O   . ARG A 1 230 ? 63.830  27.737  52.703  1.00 60.15  ? 305  ARG A O   1 
ATOM   1761  C CB  . ARG A 1 230 ? 62.754  28.940  49.835  1.00 64.10  ? 305  ARG A CB  1 
ATOM   1762  C CG  . ARG A 1 230 ? 63.091  29.871  48.686  1.00 63.27  ? 305  ARG A CG  1 
ATOM   1763  C CD  . ARG A 1 230 ? 61.978  30.886  48.468  1.00 60.54  ? 305  ARG A CD  1 
ATOM   1764  N NE  . ARG A 1 230 ? 60.686  30.252  48.223  1.00 64.01  ? 305  ARG A NE  1 
ATOM   1765  C CZ  . ARG A 1 230 ? 60.145  30.084  47.025  1.00 63.41  ? 305  ARG A CZ  1 
ATOM   1766  N NH1 . ARG A 1 230 ? 60.773  30.458  45.922  1.00 63.22  ? 305  ARG A NH1 1 
ATOM   1767  N NH2 . ARG A 1 230 ? 58.940  29.527  46.930  1.00 67.09  ? 305  ARG A NH2 1 
ATOM   1768  N N   . ALA A 1 231 ? 62.762  26.223  51.416  1.00 56.52  ? 306  ALA A N   1 
ATOM   1769  C CA  . ALA A 1 231 ? 62.338  25.429  52.565  1.00 61.23  ? 306  ALA A CA  1 
ATOM   1770  C C   . ALA A 1 231 ? 63.535  24.853  53.307  1.00 72.20  ? 306  ALA A C   1 
ATOM   1771  O O   . ALA A 1 231 ? 63.565  24.846  54.545  1.00 61.89  ? 306  ALA A O   1 
ATOM   1772  C CB  . ALA A 1 231 ? 61.399  24.311  52.113  1.00 60.89  ? 306  ALA A CB  1 
ATOM   1773  N N   . ILE A 1 232 ? 64.528  24.361  52.563  1.00 57.35  ? 307  ILE A N   1 
ATOM   1774  C CA  . ILE A 1 232 ? 65.750  23.857  53.189  1.00 43.78  ? 307  ILE A CA  1 
ATOM   1775  C C   . ILE A 1 232 ? 66.388  24.940  54.054  1.00 56.96  ? 307  ILE A C   1 
ATOM   1776  O O   . ILE A 1 232 ? 66.700  24.720  55.236  1.00 61.60  ? 307  ILE A O   1 
ATOM   1777  C CB  . ILE A 1 232 ? 66.728  23.334  52.120  1.00 46.81  ? 307  ILE A CB  1 
ATOM   1778  C CG1 . ILE A 1 232 ? 66.108  22.161  51.362  1.00 46.16  ? 307  ILE A CG1 1 
ATOM   1779  C CG2 . ILE A 1 232 ? 68.041  22.915  52.759  1.00 59.50  ? 307  ILE A CG2 1 
ATOM   1780  C CD1 . ILE A 1 232 ? 66.822  21.814  50.076  1.00 45.79  ? 307  ILE A CD1 1 
ATOM   1781  N N   . CYS A 1 233 ? 66.571  26.134  53.483  1.00 55.39  ? 308  CYS A N   1 
ATOM   1782  C CA  . CYS A 1 233 ? 67.235  27.203  54.230  1.00 53.11  ? 308  CYS A CA  1 
ATOM   1783  C C   . CYS A 1 233 ? 66.430  27.617  55.460  1.00 58.03  ? 308  CYS A C   1 
ATOM   1784  O O   . CYS A 1 233 ? 66.999  27.832  56.540  1.00 61.61  ? 308  CYS A O   1 
ATOM   1785  C CB  . CYS A 1 233 ? 67.497  28.405  53.322  1.00 49.33  ? 308  CYS A CB  1 
ATOM   1786  S SG  . CYS A 1 233 ? 68.315  28.000  51.766  1.00 66.92  ? 308  CYS A SG  1 
ATOM   1787  N N   . ILE A 1 234 ? 65.105  27.721  55.324  1.00 54.61  ? 309  ILE A N   1 
ATOM   1788  C CA  . ILE A 1 234 ? 64.267  28.150  56.444  1.00 52.66  ? 309  ILE A CA  1 
ATOM   1789  C C   . ILE A 1 234 ? 64.331  27.133  57.580  1.00 55.04  ? 309  ILE A C   1 
ATOM   1790  O O   . ILE A 1 234 ? 64.520  27.489  58.755  1.00 59.75  ? 309  ILE A O   1 
ATOM   1791  C CB  . ILE A 1 234 ? 62.819  28.378  55.969  1.00 43.47  ? 309  ILE A CB  1 
ATOM   1792  C CG1 . ILE A 1 234 ? 62.726  29.667  55.149  1.00 41.55  ? 309  ILE A CG1 1 
ATOM   1793  C CG2 . ILE A 1 234 ? 61.863  28.420  57.152  1.00 56.13  ? 309  ILE A CG2 1 
ATOM   1794  C CD1 . ILE A 1 234 ? 63.221  30.893  55.877  1.00 46.79  ? 309  ILE A CD1 1 
ATOM   1795  N N   . GLU A 1 235 ? 64.161  25.850  57.246  1.00 53.56  ? 310  GLU A N   1 
ATOM   1796  C CA  . GLU A 1 235 ? 64.242  24.800  58.255  1.00 60.94  ? 310  GLU A CA  1 
ATOM   1797  C C   . GLU A 1 235 ? 65.580  24.841  58.982  1.00 59.10  ? 310  GLU A C   1 
ATOM   1798  O O   . GLU A 1 235 ? 65.638  24.734  60.216  1.00 65.20  ? 310  GLU A O   1 
ATOM   1799  C CB  . GLU A 1 235 ? 64.022  23.434  57.601  1.00 54.15  ? 310  GLU A CB  1 
ATOM   1800  C CG  . GLU A 1 235 ? 63.381  22.401  58.510  1.00 73.62  ? 310  GLU A CG  1 
ATOM   1801  C CD  . GLU A 1 235 ? 63.568  20.978  58.011  1.00 67.60  ? 310  GLU A CD  1 
ATOM   1802  O OE1 . GLU A 1 235 ? 64.679  20.644  57.548  1.00 57.43  ? 310  GLU A OE1 1 
ATOM   1803  O OE2 . GLU A 1 235 ? 62.603  20.190  58.090  1.00 88.06  ? 310  GLU A OE2 1 
ATOM   1804  N N   . GLU A 1 236 ? 66.673  25.020  58.238  1.00 55.66  ? 311  GLU A N   1 
ATOM   1805  C CA  . GLU A 1 236 ? 67.972  24.969  58.901  1.00 60.36  ? 311  GLU A CA  1 
ATOM   1806  C C   . GLU A 1 236 ? 68.244  26.214  59.742  1.00 59.44  ? 311  GLU A C   1 
ATOM   1807  O O   . GLU A 1 236 ? 68.929  26.120  60.767  1.00 60.43  ? 311  GLU A O   1 
ATOM   1808  C CB  . GLU A 1 236 ? 69.082  24.735  57.883  1.00 57.82  ? 311  GLU A CB  1 
ATOM   1809  C CG  . GLU A 1 236 ? 69.094  23.311  57.359  1.00 61.36  ? 311  GLU A CG  1 
ATOM   1810  C CD  . GLU A 1 236 ? 69.787  22.356  58.312  1.00 57.79  ? 311  GLU A CD  1 
ATOM   1811  O OE1 . GLU A 1 236 ? 70.852  22.723  58.848  1.00 54.42  ? 311  GLU A OE1 1 
ATOM   1812  O OE2 . GLU A 1 236 ? 69.274  21.236  58.515  1.00 56.00  ? 311  GLU A OE2 1 
ATOM   1813  N N   . ILE A 1 237 ? 67.709  27.377  59.364  1.00 56.56  ? 312  ILE A N   1 
ATOM   1814  C CA  . ILE A 1 237 ? 67.874  28.532  60.246  1.00 52.34  ? 312  ILE A CA  1 
ATOM   1815  C C   . ILE A 1 237 ? 67.062  28.347  61.525  1.00 50.66  ? 312  ILE A C   1 
ATOM   1816  O O   . ILE A 1 237 ? 67.515  28.716  62.619  1.00 60.13  ? 312  ILE A O   1 
ATOM   1817  C CB  . ILE A 1 237 ? 67.532  29.852  59.523  1.00 52.25  ? 312  ILE A CB  1 
ATOM   1818  C CG1 . ILE A 1 237 ? 68.306  31.015  60.156  1.00 56.37  ? 312  ILE A CG1 1 
ATOM   1819  C CG2 . ILE A 1 237 ? 66.038  30.151  59.540  1.00 43.35  ? 312  ILE A CG2 1 
ATOM   1820  C CD1 . ILE A 1 237 ? 68.134  32.343  59.442  1.00 66.22  ? 312  ILE A CD1 1 
ATOM   1821  N N   . GLY A 1 238 ? 65.873  27.746  61.426  1.00 53.14  ? 313  GLY A N   1 
ATOM   1822  C CA  . GLY A 1 238 ? 65.159  27.385  62.642  1.00 58.97  ? 313  GLY A CA  1 
ATOM   1823  C C   . GLY A 1 238 ? 65.967  26.451  63.524  1.00 59.51  ? 313  GLY A C   1 
ATOM   1824  O O   . GLY A 1 238 ? 65.997  26.599  64.753  1.00 54.76  ? 313  GLY A O   1 
ATOM   1825  N N   . ILE A 1 239 ? 66.644  25.481  62.903  1.00 50.19  ? 314  ILE A N   1 
ATOM   1826  C CA  . ILE A 1 239 ? 67.473  24.544  63.659  1.00 51.45  ? 314  ILE A CA  1 
ATOM   1827  C C   . ILE A 1 239 ? 68.613  25.276  64.360  1.00 55.97  ? 314  ILE A C   1 
ATOM   1828  O O   . ILE A 1 239 ? 68.928  24.994  65.522  1.00 58.61  ? 314  ILE A O   1 
ATOM   1829  C CB  . ILE A 1 239 ? 68.002  23.434  62.733  1.00 46.66  ? 314  ILE A CB  1 
ATOM   1830  C CG1 . ILE A 1 239 ? 66.874  22.477  62.363  1.00 45.48  ? 314  ILE A CG1 1 
ATOM   1831  C CG2 . ILE A 1 239 ? 69.134  22.670  63.399  1.00 50.89  ? 314  ILE A CG2 1 
ATOM   1832  C CD1 . ILE A 1 239 ? 67.086  21.789  61.039  1.00 56.84  ? 314  ILE A CD1 1 
ATOM   1833  N N   . TRP A 1 240 ? 69.262  26.212  63.662  1.00 50.11  ? 315  TRP A N   1 
ATOM   1834  C CA  . TRP A 1 240 ? 70.340  26.980  64.285  1.00 47.13  ? 315  TRP A CA  1 
ATOM   1835  C C   . TRP A 1 240 ? 69.829  27.788  65.470  1.00 49.77  ? 315  TRP A C   1 
ATOM   1836  O O   . TRP A 1 240 ? 70.498  27.879  66.506  1.00 53.11  ? 315  TRP A O   1 
ATOM   1837  C CB  . TRP A 1 240 ? 70.993  27.914  63.268  1.00 47.58  ? 315  TRP A CB  1 
ATOM   1838  C CG  . TRP A 1 240 ? 71.387  27.255  62.001  1.00 50.87  ? 315  TRP A CG  1 
ATOM   1839  C CD1 . TRP A 1 240 ? 71.691  25.938  61.817  1.00 52.44  ? 315  TRP A CD1 1 
ATOM   1840  C CD2 . TRP A 1 240 ? 71.487  27.875  60.717  1.00 52.36  ? 315  TRP A CD2 1 
ATOM   1841  N NE1 . TRP A 1 240 ? 71.989  25.704  60.497  1.00 65.63  ? 315  TRP A NE1 1 
ATOM   1842  C CE2 . TRP A 1 240 ? 71.871  26.877  59.801  1.00 56.41  ? 315  TRP A CE2 1 
ATOM   1843  C CE3 . TRP A 1 240 ? 71.298  29.180  60.254  1.00 52.84  ? 315  TRP A CE3 1 
ATOM   1844  C CZ2 . TRP A 1 240 ? 72.067  27.143  58.449  1.00 56.60  ? 315  TRP A CZ2 1 
ATOM   1845  C CZ3 . TRP A 1 240 ? 71.491  29.442  58.913  1.00 58.09  ? 315  TRP A CZ3 1 
ATOM   1846  C CH2 . TRP A 1 240 ? 71.872  28.429  58.025  1.00 59.29  ? 315  TRP A CH2 1 
ATOM   1847  N N   . MET A 1 241 ? 68.649  28.398  65.329  1.00 48.78  ? 316  MET A N   1 
ATOM   1848  C CA  . MET A 1 241 ? 68.096  29.190  66.424  1.00 48.50  ? 316  MET A CA  1 
ATOM   1849  C C   . MET A 1 241 ? 67.801  28.324  67.642  1.00 49.48  ? 316  MET A C   1 
ATOM   1850  O O   . MET A 1 241 ? 68.104  28.716  68.774  1.00 58.94  ? 316  MET A O   1 
ATOM   1851  C CB  . MET A 1 241 ? 66.838  29.921  65.961  1.00 64.86  ? 316  MET A CB  1 
ATOM   1852  C CG  . MET A 1 241 ? 67.101  30.917  64.846  1.00 51.57  ? 316  MET A CG  1 
ATOM   1853  S SD  . MET A 1 241 ? 65.821  32.160  64.635  1.00 70.99  ? 316  MET A SD  1 
ATOM   1854  C CE  . MET A 1 241 ? 65.710  32.170  62.850  1.00 51.51  ? 316  MET A CE  1 
ATOM   1855  N N   . LYS A 1 242 ? 67.216  27.141  67.431  1.00 49.30  ? 317  LYS A N   1 
ATOM   1856  C CA  . LYS A 1 242 ? 66.986  26.229  68.553  1.00 49.84  ? 317  LYS A CA  1 
ATOM   1857  C C   . LYS A 1 242 ? 68.293  25.740  69.172  1.00 58.29  ? 317  LYS A C   1 
ATOM   1858  O O   . LYS A 1 242 ? 68.420  25.670  70.401  1.00 57.69  ? 317  LYS A O   1 
ATOM   1859  C CB  . LYS A 1 242 ? 66.143  25.038  68.106  1.00 59.64  ? 317  LYS A CB  1 
ATOM   1860  C CG  . LYS A 1 242 ? 64.713  25.058  68.605  1.00 84.42  ? 317  LYS A CG  1 
ATOM   1861  C CD  . LYS A 1 242 ? 64.634  24.388  69.968  1.00 91.40  ? 317  LYS A CD  1 
ATOM   1862  C CE  . LYS A 1 242 ? 63.213  24.365  70.486  1.00 83.20  ? 317  LYS A CE  1 
ATOM   1863  N NZ  . LYS A 1 242 ? 63.067  23.569  71.734  1.00 91.65  ? 317  LYS A NZ  1 
ATOM   1864  N N   . MET A 1 243 ? 69.273  25.395  68.335  1.00 58.75  ? 318  MET A N   1 
ATOM   1865  C CA  . MET A 1 243 ? 70.504  24.769  68.807  1.00 60.14  ? 318  MET A CA  1 
ATOM   1866  C C   . MET A 1 243 ? 71.287  25.701  69.720  1.00 57.79  ? 318  MET A C   1 
ATOM   1867  O O   . MET A 1 243 ? 71.751  25.301  70.795  1.00 50.32  ? 318  MET A O   1 
ATOM   1868  C CB  . MET A 1 243 ? 71.356  24.383  67.600  1.00 45.76  ? 318  MET A CB  1 
ATOM   1869  C CG  . MET A 1 243 ? 72.576  23.535  67.881  1.00 50.89  ? 318  MET A CG  1 
ATOM   1870  S SD  . MET A 1 243 ? 73.323  23.020  66.321  1.00 68.23  ? 318  MET A SD  1 
ATOM   1871  C CE  . MET A 1 243 ? 72.198  23.770  65.139  1.00 48.32  ? 318  MET A CE  1 
ATOM   1872  N N   . TYR A 1 244 ? 71.452  26.952  69.291  1.00 61.71  ? 319  TYR A N   1 
ATOM   1873  C CA  . TYR A 1 244 ? 72.350  27.918  69.919  1.00 58.55  ? 319  TYR A CA  1 
ATOM   1874  C C   . TYR A 1 244 ? 71.566  29.219  70.110  1.00 57.56  ? 319  TYR A C   1 
ATOM   1875  O O   . TYR A 1 244 ? 71.770  30.198  69.392  1.00 59.21  ? 319  TYR A O   1 
ATOM   1876  C CB  . TYR A 1 244 ? 73.597  28.119  69.056  1.00 61.85  ? 319  TYR A CB  1 
ATOM   1877  C CG  . TYR A 1 244 ? 74.801  28.723  69.750  1.00 58.27  ? 319  TYR A CG  1 
ATOM   1878  C CD1 . TYR A 1 244 ? 74.731  29.176  71.061  1.00 57.52  ? 319  TYR A CD1 1 
ATOM   1879  C CD2 . TYR A 1 244 ? 76.014  28.838  69.081  1.00 59.08  ? 319  TYR A CD2 1 
ATOM   1880  C CE1 . TYR A 1 244 ? 75.842  29.726  71.684  1.00 73.80  ? 319  TYR A CE1 1 
ATOM   1881  C CE2 . TYR A 1 244 ? 77.124  29.384  69.693  1.00 46.58  ? 319  TYR A CE2 1 
ATOM   1882  C CZ  . TYR A 1 244 ? 77.034  29.826  70.993  1.00 55.27  ? 319  TYR A CZ  1 
ATOM   1883  O OH  . TYR A 1 244 ? 78.138  30.373  71.605  1.00 60.54  ? 319  TYR A OH  1 
ATOM   1884  N N   . SER A 1 245 ? 70.658  29.213  71.089  1.00 60.56  ? 320  SER A N   1 
ATOM   1885  C CA  . SER A 1 245 ? 69.708  30.311  71.224  1.00 59.88  ? 320  SER A CA  1 
ATOM   1886  C C   . SER A 1 245 ? 70.411  31.630  71.520  1.00 59.28  ? 320  SER A C   1 
ATOM   1887  O O   . SER A 1 245 ? 70.027  32.677  70.988  1.00 63.14  ? 320  SER A O   1 
ATOM   1888  C CB  . SER A 1 245 ? 68.687  29.989  72.314  1.00 55.67  ? 320  SER A CB  1 
ATOM   1889  O OG  . SER A 1 245 ? 68.173  31.173  72.893  1.00 78.62  ? 320  SER A OG  1 
ATOM   1890  N N   . ASP A 1 246 ? 71.446  31.602  72.364  1.00 59.69  ? 321  ASP A N   1 
ATOM   1891  C CA  . ASP A 1 246 ? 72.106  32.845  72.754  1.00 68.35  ? 321  ASP A CA  1 
ATOM   1892  C C   . ASP A 1 246 ? 72.795  33.525  71.577  1.00 56.91  ? 321  ASP A C   1 
ATOM   1893  O O   . ASP A 1 246 ? 72.957  34.751  71.584  1.00 62.25  ? 321  ASP A O   1 
ATOM   1894  C CB  . ASP A 1 246 ? 73.112  32.577  73.872  1.00 68.68  ? 321  ASP A CB  1 
ATOM   1895  C CG  . ASP A 1 246 ? 72.523  31.748  74.993  1.00 77.25  ? 321  ASP A CG  1 
ATOM   1896  O OD1 . ASP A 1 246 ? 72.899  30.565  75.123  1.00 87.66  ? 321  ASP A OD1 1 
ATOM   1897  O OD2 . ASP A 1 246 ? 71.679  32.282  75.744  1.00 90.56  ? 321  ASP A OD2 1 
ATOM   1898  N N   . ALA A 1 247 ? 73.195  32.760  70.559  1.00 40.99  ? 322  ALA A N   1 
ATOM   1899  C CA  . ALA A 1 247 ? 73.924  33.312  69.427  1.00 45.81  ? 322  ALA A CA  1 
ATOM   1900  C C   . ALA A 1 247 ? 73.104  33.432  68.152  1.00 68.49  ? 322  ALA A C   1 
ATOM   1901  O O   . ALA A 1 247 ? 73.498  34.188  67.258  1.00 69.62  ? 322  ALA A O   1 
ATOM   1902  C CB  . ALA A 1 247 ? 75.166  32.460  69.126  1.00 50.36  ? 322  ALA A CB  1 
ATOM   1903  N N   . PHE A 1 248 ? 71.988  32.710  68.034  1.00 72.30  ? 323  PHE A N   1 
ATOM   1904  C CA  . PHE A 1 248 ? 71.206  32.721  66.806  1.00 61.95  ? 323  PHE A CA  1 
ATOM   1905  C C   . PHE A 1 248 ? 69.744  33.099  66.990  1.00 62.91  ? 323  PHE A C   1 
ATOM   1906  O O   . PHE A 1 248 ? 69.050  33.292  65.986  1.00 61.92  ? 323  PHE A O   1 
ATOM   1907  C CB  . PHE A 1 248 ? 71.286  31.354  66.109  1.00 49.46  ? 323  PHE A CB  1 
ATOM   1908  C CG  . PHE A 1 248 ? 72.598  31.107  65.423  1.00 47.35  ? 323  PHE A CG  1 
ATOM   1909  C CD1 . PHE A 1 248 ? 73.688  30.626  66.132  1.00 47.67  ? 323  PHE A CD1 1 
ATOM   1910  C CD2 . PHE A 1 248 ? 72.747  31.373  64.074  1.00 48.16  ? 323  PHE A CD2 1 
ATOM   1911  C CE1 . PHE A 1 248 ? 74.899  30.401  65.501  1.00 38.20  ? 323  PHE A CE1 1 
ATOM   1912  C CE2 . PHE A 1 248 ? 73.952  31.153  63.439  1.00 47.42  ? 323  PHE A CE2 1 
ATOM   1913  C CZ  . PHE A 1 248 ? 75.031  30.667  64.153  1.00 40.08  ? 323  PHE A CZ  1 
ATOM   1914  N N   . LEU A 1 249 ? 69.253  33.214  68.226  1.00 52.37  ? 324  LEU A N   1 
ATOM   1915  C CA  . LEU A 1 249 ? 67.892  33.695  68.461  1.00 60.46  ? 324  LEU A CA  1 
ATOM   1916  C C   . LEU A 1 249 ? 67.944  35.215  68.583  1.00 60.78  ? 324  LEU A C   1 
ATOM   1917  O O   . LEU A 1 249 ? 67.924  35.793  69.672  1.00 64.44  ? 324  LEU A O   1 
ATOM   1918  C CB  . LEU A 1 249 ? 67.285  33.040  69.694  1.00 57.94  ? 324  LEU A CB  1 
ATOM   1919  C CG  . LEU A 1 249 ? 65.765  33.113  69.834  1.00 53.73  ? 324  LEU A CG  1 
ATOM   1920  C CD1 . LEU A 1 249 ? 65.085  33.096  68.474  1.00 53.00  ? 324  LEU A CD1 1 
ATOM   1921  C CD2 . LEU A 1 249 ? 65.262  31.975  70.704  1.00 67.70  ? 324  LEU A CD2 1 
ATOM   1922  N N   . ASN A 1 250 ? 68.030  35.868  67.426  1.00 70.44  ? 325  ASN A N   1 
ATOM   1923  C CA  . ASN A 1 250 ? 68.049  37.319  67.346  1.00 77.41  ? 325  ASN A CA  1 
ATOM   1924  C C   . ASN A 1 250 ? 67.108  37.761  66.236  1.00 76.06  ? 325  ASN A C   1 
ATOM   1925  O O   . ASN A 1 250 ? 66.691  36.963  65.392  1.00 72.01  ? 325  ASN A O   1 
ATOM   1926  C CB  . ASN A 1 250 ? 69.462  37.858  67.087  1.00 74.39  ? 325  ASN A CB  1 
ATOM   1927  C CG  . ASN A 1 250 ? 70.531  37.052  67.796  1.00 97.81  ? 325  ASN A CG  1 
ATOM   1928  O OD1 . ASN A 1 250 ? 70.583  37.011  69.027  1.00 116.19 ? 325  ASN A OD1 1 
ATOM   1929  N ND2 . ASN A 1 250 ? 71.391  36.403  67.021  1.00 83.56  ? 325  ASN A ND2 1 
ATOM   1930  N N   . ASP A 1 251 ? 66.770  39.052  66.246  1.00 70.47  ? 326  ASP A N   1 
ATOM   1931  C CA  . ASP A 1 251 ? 65.971  39.604  65.158  1.00 61.03  ? 326  ASP A CA  1 
ATOM   1932  C C   . ASP A 1 251 ? 66.701  39.498  63.826  1.00 67.45  ? 326  ASP A C   1 
ATOM   1933  O O   . ASP A 1 251 ? 66.063  39.314  62.782  1.00 69.81  ? 326  ASP A O   1 
ATOM   1934  C CB  . ASP A 1 251 ? 65.609  41.062  65.453  1.00 90.22  ? 326  ASP A CB  1 
ATOM   1935  C CG  . ASP A 1 251 ? 64.989  41.248  66.825  1.00 94.77  ? 326  ASP A CG  1 
ATOM   1936  O OD1 . ASP A 1 251 ? 64.070  40.479  67.173  1.00 80.44  ? 326  ASP A OD1 1 
ATOM   1937  O OD2 . ASP A 1 251 ? 65.414  42.169  67.553  1.00 100.98 ? 326  ASP A OD2 1 
ATOM   1938  N N   . SER A 1 252 ? 68.035  39.590  63.849  1.00 76.96  ? 327  SER A N   1 
ATOM   1939  C CA  . SER A 1 252 ? 68.824  39.512  62.623  1.00 76.04  ? 327  SER A CA  1 
ATOM   1940  C C   . SER A 1 252 ? 68.629  38.182  61.908  1.00 75.14  ? 327  SER A C   1 
ATOM   1941  O O   . SER A 1 252 ? 68.761  38.113  60.680  1.00 80.73  ? 327  SER A O   1 
ATOM   1942  C CB  . SER A 1 252 ? 70.302  39.729  62.942  1.00 82.58  ? 327  SER A CB  1 
ATOM   1943  O OG  . SER A 1 252 ? 70.774  38.738  63.840  1.00 97.96  ? 327  SER A OG  1 
ATOM   1944  N N   . TYR A 1 253 ? 68.330  37.119  62.652  1.00 72.97  ? 328  TYR A N   1 
ATOM   1945  C CA  . TYR A 1 253 ? 68.021  35.822  62.068  1.00 66.55  ? 328  TYR A CA  1 
ATOM   1946  C C   . TYR A 1 253 ? 66.523  35.591  61.936  1.00 68.01  ? 328  TYR A C   1 
ATOM   1947  O O   . TYR A 1 253 ? 66.074  34.992  60.954  1.00 72.05  ? 328  TYR A O   1 
ATOM   1948  C CB  . TYR A 1 253 ? 68.634  34.701  62.912  1.00 61.98  ? 328  TYR A CB  1 
ATOM   1949  C CG  . TYR A 1 253 ? 70.145  34.690  62.905  1.00 64.88  ? 328  TYR A CG  1 
ATOM   1950  C CD1 . TYR A 1 253 ? 70.854  34.301  61.776  1.00 63.09  ? 328  TYR A CD1 1 
ATOM   1951  C CD2 . TYR A 1 253 ? 70.863  35.071  64.030  1.00 64.40  ? 328  TYR A CD2 1 
ATOM   1952  C CE1 . TYR A 1 253 ? 72.237  34.290  61.769  1.00 50.62  ? 328  TYR A CE1 1 
ATOM   1953  C CE2 . TYR A 1 253 ? 72.243  35.064  64.033  1.00 61.67  ? 328  TYR A CE2 1 
ATOM   1954  C CZ  . TYR A 1 253 ? 72.925  34.672  62.900  1.00 50.30  ? 328  TYR A CZ  1 
ATOM   1955  O OH  . TYR A 1 253 ? 74.301  34.664  62.896  1.00 70.18  ? 328  TYR A OH  1 
ATOM   1956  N N   . LEU A 1 254 ? 65.740  36.072  62.907  1.00 61.33  ? 329  LEU A N   1 
ATOM   1957  C CA  . LEU A 1 254 ? 64.299  35.852  62.893  1.00 52.81  ? 329  LEU A CA  1 
ATOM   1958  C C   . LEU A 1 254 ? 63.627  36.562  61.725  1.00 53.66  ? 329  LEU A C   1 
ATOM   1959  O O   . LEU A 1 254 ? 62.543  36.148  61.292  1.00 54.82  ? 329  LEU A O   1 
ATOM   1960  C CB  . LEU A 1 254 ? 63.689  36.326  64.214  1.00 48.86  ? 329  LEU A CB  1 
ATOM   1961  C CG  . LEU A 1 254 ? 63.749  35.384  65.417  1.00 49.18  ? 329  LEU A CG  1 
ATOM   1962  C CD1 . LEU A 1 254 ? 63.560  36.167  66.704  1.00 53.12  ? 329  LEU A CD1 1 
ATOM   1963  C CD2 . LEU A 1 254 ? 62.700  34.293  65.299  1.00 55.26  ? 329  LEU A CD2 1 
ATOM   1964  N N   . LYS A 1 255 ? 64.242  37.635  61.216  1.00 55.94  ? 330  LYS A N   1 
ATOM   1965  C CA  . LYS A 1 255 ? 63.611  38.406  60.150  1.00 41.66  ? 330  LYS A CA  1 
ATOM   1966  C C   . LYS A 1 255 ? 63.410  37.568  58.899  1.00 50.77  ? 330  LYS A C   1 
ATOM   1967  O O   . LYS A 1 255 ? 62.437  37.772  58.168  1.00 59.67  ? 330  LYS A O   1 
ATOM   1968  C CB  . LYS A 1 255 ? 64.442  39.645  59.810  1.00 51.19  ? 330  LYS A CB  1 
ATOM   1969  C CG  . LYS A 1 255 ? 65.875  39.355  59.396  1.00 64.28  ? 330  LYS A CG  1 
ATOM   1970  C CD  . LYS A 1 255 ? 66.739  40.595  59.523  1.00 62.03  ? 330  LYS A CD  1 
ATOM   1971  C CE  . LYS A 1 255 ? 67.840  40.604  58.478  1.00 64.32  ? 330  LYS A CE  1 
ATOM   1972  N NZ  . LYS A 1 255 ? 68.404  41.965  58.276  1.00 71.92  ? 330  LYS A NZ  1 
ATOM   1973  N N   . TYR A 1 256 ? 64.310  36.621  58.636  1.00 53.73  ? 331  TYR A N   1 
ATOM   1974  C CA  . TYR A 1 256 ? 64.178  35.801  57.438  1.00 59.80  ? 331  TYR A CA  1 
ATOM   1975  C C   . TYR A 1 256 ? 62.968  34.885  57.540  1.00 53.01  ? 331  TYR A C   1 
ATOM   1976  O O   . TYR A 1 256 ? 62.202  34.748  56.578  1.00 50.84  ? 331  TYR A O   1 
ATOM   1977  C CB  . TYR A 1 256 ? 65.458  35.000  57.216  1.00 61.98  ? 331  TYR A CB  1 
ATOM   1978  C CG  . TYR A 1 256 ? 66.650  35.880  56.929  1.00 64.22  ? 331  TYR A CG  1 
ATOM   1979  C CD1 . TYR A 1 256 ? 66.832  36.450  55.676  1.00 62.39  ? 331  TYR A CD1 1 
ATOM   1980  C CD2 . TYR A 1 256 ? 67.580  36.162  57.919  1.00 61.12  ? 331  TYR A CD2 1 
ATOM   1981  C CE1 . TYR A 1 256 ? 67.917  37.263  55.414  1.00 61.83  ? 331  TYR A CE1 1 
ATOM   1982  C CE2 . TYR A 1 256 ? 68.667  36.974  57.667  1.00 66.31  ? 331  TYR A CE2 1 
ATOM   1983  C CZ  . TYR A 1 256 ? 68.831  37.522  56.413  1.00 63.96  ? 331  TYR A CZ  1 
ATOM   1984  O OH  . TYR A 1 256 ? 69.914  38.331  56.160  1.00 66.83  ? 331  TYR A OH  1 
ATOM   1985  N N   . VAL A 1 257 ? 62.769  34.266  58.706  1.00 58.25  ? 332  VAL A N   1 
ATOM   1986  C CA  . VAL A 1 257 ? 61.576  33.451  58.919  1.00 58.53  ? 332  VAL A CA  1 
ATOM   1987  C C   . VAL A 1 257 ? 60.325  34.312  58.827  1.00 56.36  ? 332  VAL A C   1 
ATOM   1988  O O   . VAL A 1 257 ? 59.325  33.918  58.214  1.00 57.59  ? 332  VAL A O   1 
ATOM   1989  C CB  . VAL A 1 257 ? 61.660  32.719  60.272  1.00 48.71  ? 332  VAL A CB  1 
ATOM   1990  C CG1 . VAL A 1 257 ? 60.425  31.861  60.489  1.00 50.06  ? 332  VAL A CG1 1 
ATOM   1991  C CG2 . VAL A 1 257 ? 62.916  31.870  60.335  1.00 43.14  ? 332  VAL A CG2 1 
ATOM   1992  N N   . GLY A 1 258 ? 60.364  35.507  59.422  1.00 51.30  ? 333  GLY A N   1 
ATOM   1993  C CA  . GLY A 1 258 ? 59.198  36.376  59.382  1.00 47.96  ? 333  GLY A CA  1 
ATOM   1994  C C   . GLY A 1 258 ? 58.836  36.809  57.973  1.00 58.92  ? 333  GLY A C   1 
ATOM   1995  O O   . GLY A 1 258 ? 57.658  36.862  57.611  1.00 59.84  ? 333  GLY A O   1 
ATOM   1996  N N   . TRP A 1 259 ? 59.846  37.121  57.160  1.00 52.11  ? 334  TRP A N   1 
ATOM   1997  C CA  . TRP A 1 259 ? 59.608  37.521  55.779  1.00 47.99  ? 334  TRP A CA  1 
ATOM   1998  C C   . TRP A 1 259 ? 59.086  36.350  54.961  1.00 62.65  ? 334  TRP A C   1 
ATOM   1999  O O   . TRP A 1 259 ? 58.116  36.486  54.205  1.00 68.05  ? 334  TRP A O   1 
ATOM   2000  C CB  . TRP A 1 259 ? 60.901  38.055  55.164  1.00 42.02  ? 334  TRP A CB  1 
ATOM   2001  C CG  . TRP A 1 259 ? 61.412  39.294  55.812  1.00 54.54  ? 334  TRP A CG  1 
ATOM   2002  C CD1 . TRP A 1 259 ? 60.710  40.167  56.591  1.00 54.22  ? 334  TRP A CD1 1 
ATOM   2003  C CD2 . TRP A 1 259 ? 62.757  39.779  55.777  1.00 64.84  ? 334  TRP A CD2 1 
ATOM   2004  N NE1 . TRP A 1 259 ? 61.532  41.181  57.022  1.00 58.36  ? 334  TRP A NE1 1 
ATOM   2005  C CE2 . TRP A 1 259 ? 62.795  40.964  56.537  1.00 60.22  ? 334  TRP A CE2 1 
ATOM   2006  C CE3 . TRP A 1 259 ? 63.934  39.330  55.166  1.00 56.77  ? 334  TRP A CE3 1 
ATOM   2007  C CZ2 . TRP A 1 259 ? 63.964  41.707  56.704  1.00 60.84  ? 334  TRP A CZ2 1 
ATOM   2008  C CZ3 . TRP A 1 259 ? 65.091  40.068  55.333  1.00 63.38  ? 334  TRP A CZ3 1 
ATOM   2009  C CH2 . TRP A 1 259 ? 65.097  41.243  56.095  1.00 59.43  ? 334  TRP A CH2 1 
ATOM   2010  N N   . THR A 1 260 ? 59.720  35.185  55.102  1.00 57.19  ? 335  THR A N   1 
ATOM   2011  C CA  . THR A 1 260 ? 59.367  34.028  54.298  1.00 48.09  ? 335  THR A CA  1 
ATOM   2012  C C   . THR A 1 260 ? 58.081  33.368  54.777  1.00 58.57  ? 335  THR A C   1 
ATOM   2013  O O   . THR A 1 260 ? 57.581  32.454  54.114  1.00 71.77  ? 335  THR A O   1 
ATOM   2014  C CB  . THR A 1 260 ? 60.535  33.045  54.317  1.00 48.52  ? 335  THR A CB  1 
ATOM   2015  O OG1 . THR A 1 260 ? 61.756  33.787  54.281  1.00 55.45  ? 335  THR A OG1 1 
ATOM   2016  C CG2 . THR A 1 260 ? 60.520  32.210  53.074  1.00 63.38  ? 335  THR A CG2 1 
ATOM   2017  N N   . MET A 1 261 ? 57.540  33.812  55.915  1.00 56.46  ? 336  MET A N   1 
ATOM   2018  C CA  . MET A 1 261 ? 56.173  33.467  56.288  1.00 55.68  ? 336  MET A CA  1 
ATOM   2019  C C   . MET A 1 261 ? 55.167  33.899  55.229  1.00 60.33  ? 336  MET A C   1 
ATOM   2020  O O   . MET A 1 261 ? 54.069  33.335  55.161  1.00 62.85  ? 336  MET A O   1 
ATOM   2021  C CB  . MET A 1 261 ? 55.819  34.126  57.622  1.00 53.63  ? 336  MET A CB  1 
ATOM   2022  C CG  . MET A 1 261 ? 56.132  33.293  58.848  1.00 58.51  ? 336  MET A CG  1 
ATOM   2023  S SD  . MET A 1 261 ? 55.482  34.051  60.350  1.00 67.74  ? 336  MET A SD  1 
ATOM   2024  C CE  . MET A 1 261 ? 55.371  35.763  59.843  1.00 57.93  ? 336  MET A CE  1 
ATOM   2025  N N   . HIS A 1 262 ? 55.515  34.893  54.413  1.00 61.49  ? 337  HIS A N   1 
ATOM   2026  C CA  . HIS A 1 262 ? 54.633  35.430  53.388  1.00 62.95  ? 337  HIS A CA  1 
ATOM   2027  C C   . HIS A 1 262 ? 54.874  34.798  52.023  1.00 66.58  ? 337  HIS A C   1 
ATOM   2028  O O   . HIS A 1 262 ? 54.320  35.272  51.024  1.00 49.84  ? 337  HIS A O   1 
ATOM   2029  C CB  . HIS A 1 262 ? 54.804  36.948  53.298  1.00 56.38  ? 337  HIS A CB  1 
ATOM   2030  C CG  . HIS A 1 262 ? 54.561  37.659  54.592  1.00 55.16  ? 337  HIS A CG  1 
ATOM   2031  N ND1 . HIS A 1 262 ? 55.470  37.649  55.629  1.00 58.10  ? 337  HIS A ND1 1 
ATOM   2032  C CD2 . HIS A 1 262 ? 53.507  38.392  55.023  1.00 64.57  ? 337  HIS A CD2 1 
ATOM   2033  C CE1 . HIS A 1 262 ? 54.988  38.350  56.640  1.00 66.14  ? 337  HIS A CE1 1 
ATOM   2034  N NE2 . HIS A 1 262 ? 53.798  38.811  56.298  1.00 63.18  ? 337  HIS A NE2 1 
ATOM   2035  N N   . ASP A 1 263 ? 55.692  33.748  51.959  1.00 67.43  ? 338  ASP A N   1 
ATOM   2036  C CA  . ASP A 1 263 ? 55.954  33.070  50.697  1.00 61.77  ? 338  ASP A CA  1 
ATOM   2037  C C   . ASP A 1 263 ? 54.666  32.485  50.133  1.00 60.56  ? 338  ASP A C   1 
ATOM   2038  O O   . ASP A 1 263 ? 53.846  31.924  50.865  1.00 59.88  ? 338  ASP A O   1 
ATOM   2039  C CB  . ASP A 1 263 ? 57.000  31.970  50.903  1.00 57.36  ? 338  ASP A CB  1 
ATOM   2040  C CG  . ASP A 1 263 ? 57.655  31.534  49.609  1.00 56.61  ? 338  ASP A CG  1 
ATOM   2041  O OD1 . ASP A 1 263 ? 57.004  30.812  48.827  1.00 54.21  ? 338  ASP A OD1 1 
ATOM   2042  O OD2 . ASP A 1 263 ? 58.820  31.916  49.375  1.00 58.72  ? 338  ASP A OD2 1 
ATOM   2043  N N   . LYS A 1 264 ? 54.486  32.626  48.816  1.00 59.87  ? 339  LYS A N   1 
ATOM   2044  C CA  . LYS A 1 264 ? 53.267  32.134  48.179  1.00 63.09  ? 339  LYS A CA  1 
ATOM   2045  C C   . LYS A 1 264 ? 53.143  30.619  48.290  1.00 64.35  ? 339  LYS A C   1 
ATOM   2046  O O   . LYS A 1 264 ? 52.028  30.092  48.381  1.00 84.01  ? 339  LYS A O   1 
ATOM   2047  C CB  . LYS A 1 264 ? 53.227  32.564  46.711  1.00 61.37  ? 339  LYS A CB  1 
ATOM   2048  C CG  . LYS A 1 264 ? 53.220  34.072  46.488  1.00 70.62  ? 339  LYS A CG  1 
ATOM   2049  C CD  . LYS A 1 264 ? 52.059  34.744  47.210  1.00 66.19  ? 339  LYS A CD  1 
ATOM   2050  C CE  . LYS A 1 264 ? 52.493  36.032  47.892  1.00 79.98  ? 339  LYS A CE  1 
ATOM   2051  N NZ  . LYS A 1 264 ? 51.673  36.329  49.100  1.00 65.31  ? 339  LYS A NZ  1 
ATOM   2052  N N   . GLN A 1 265 ? 54.264  29.904  48.288  1.00 67.81  ? 340  GLN A N   1 
ATOM   2053  C CA  . GLN A 1 265 ? 54.233  28.452  48.402  1.00 61.05  ? 340  GLN A CA  1 
ATOM   2054  C C   . GLN A 1 265 ? 53.950  28.030  49.839  1.00 68.41  ? 340  GLN A C   1 
ATOM   2055  O O   . GLN A 1 265 ? 54.524  28.573  50.788  1.00 76.65  ? 340  GLN A O   1 
ATOM   2056  C CB  . GLN A 1 265 ? 55.556  27.858  47.925  1.00 61.12  ? 340  GLN A CB  1 
ATOM   2057  C CG  . GLN A 1 265 ? 55.803  28.053  46.442  1.00 67.62  ? 340  GLN A CG  1 
ATOM   2058  C CD  . GLN A 1 265 ? 54.711  27.442  45.592  1.00 72.70  ? 340  GLN A CD  1 
ATOM   2059  O OE1 . GLN A 1 265 ? 53.972  28.153  44.913  1.00 55.99  ? 340  GLN A OE1 1 
ATOM   2060  N NE2 . GLN A 1 265 ? 54.605  26.118  45.622  1.00 96.29  ? 340  GLN A NE2 1 
ATOM   2061  N N   . GLY A 1 266 ? 53.059  27.047  49.994  1.00 68.58  ? 341  GLY A N   1 
ATOM   2062  C CA  . GLY A 1 266 ? 52.656  26.619  51.324  1.00 67.59  ? 341  GLY A CA  1 
ATOM   2063  C C   . GLY A 1 266 ? 53.682  25.769  52.043  1.00 66.49  ? 341  GLY A C   1 
ATOM   2064  O O   . GLY A 1 266 ? 53.750  25.791  53.277  1.00 58.65  ? 341  GLY A O   1 
ATOM   2065  N N   . GLU A 1 267 ? 54.477  25.002  51.294  1.00 66.71  ? 342  GLU A N   1 
ATOM   2066  C CA  . GLU A 1 267 ? 55.561  24.227  51.889  1.00 80.56  ? 342  GLU A CA  1 
ATOM   2067  C C   . GLU A 1 267 ? 56.499  25.121  52.694  1.00 73.46  ? 342  GLU A C   1 
ATOM   2068  O O   . GLU A 1 267 ? 56.835  24.827  53.852  1.00 72.28  ? 342  GLU A O   1 
ATOM   2069  C CB  . GLU A 1 267 ? 56.307  23.485  50.775  1.00 88.57  ? 342  GLU A CB  1 
ATOM   2070  C CG  . GLU A 1 267 ? 56.285  24.238  49.441  1.00 93.76  ? 342  GLU A CG  1 
ATOM   2071  C CD  . GLU A 1 267 ? 56.986  23.501  48.313  1.00 100.69 ? 342  GLU A CD  1 
ATOM   2072  O OE1 . GLU A 1 267 ? 58.069  22.926  48.551  1.00 89.48  ? 342  GLU A OE1 1 
ATOM   2073  O OE2 . GLU A 1 267 ? 56.447  23.500  47.184  1.00 88.59  ? 342  GLU A OE2 1 
ATOM   2074  N N   . VAL A 1 268 ? 56.899  26.244  52.098  1.00 54.80  ? 343  VAL A N   1 
ATOM   2075  C CA  . VAL A 1 268 ? 57.802  27.175  52.763  1.00 60.09  ? 343  VAL A CA  1 
ATOM   2076  C C   . VAL A 1 268 ? 57.139  27.771  54.003  1.00 60.04  ? 343  VAL A C   1 
ATOM   2077  O O   . VAL A 1 268 ? 57.773  27.929  55.058  1.00 63.58  ? 343  VAL A O   1 
ATOM   2078  C CB  . VAL A 1 268 ? 58.239  28.261  51.763  1.00 58.54  ? 343  VAL A CB  1 
ATOM   2079  C CG1 . VAL A 1 268 ? 59.241  29.176  52.392  1.00 62.71  ? 343  VAL A CG1 1 
ATOM   2080  C CG2 . VAL A 1 268 ? 58.794  27.623  50.492  1.00 61.86  ? 343  VAL A CG2 1 
ATOM   2081  N N   . ARG A 1 269 ? 55.848  28.099  53.896  1.00 55.34  ? 344  ARG A N   1 
ATOM   2082  C CA  . ARG A 1 269 ? 55.118  28.670  55.023  1.00 60.74  ? 344  ARG A CA  1 
ATOM   2083  C C   . ARG A 1 269 ? 55.081  27.704  56.202  1.00 65.46  ? 344  ARG A C   1 
ATOM   2084  O O   . ARG A 1 269 ? 55.297  28.102  57.356  1.00 71.53  ? 344  ARG A O   1 
ATOM   2085  C CB  . ARG A 1 269 ? 53.699  29.037  54.581  1.00 56.59  ? 344  ARG A CB  1 
ATOM   2086  C CG  . ARG A 1 269 ? 53.588  30.417  53.937  1.00 64.14  ? 344  ARG A CG  1 
ATOM   2087  C CD  . ARG A 1 269 ? 52.144  30.895  53.809  1.00 68.53  ? 344  ARG A CD  1 
ATOM   2088  N NE  . ARG A 1 269 ? 51.241  29.878  53.280  1.00 68.24  ? 344  ARG A NE  1 
ATOM   2089  C CZ  . ARG A 1 269 ? 50.905  29.764  52.001  1.00 61.02  ? 344  ARG A CZ  1 
ATOM   2090  N NH1 . ARG A 1 269 ? 51.405  30.571  51.080  1.00 57.60  ? 344  ARG A NH1 1 
ATOM   2091  N NH2 . ARG A 1 269 ? 50.041  28.819  51.638  1.00 60.20  ? 344  ARG A NH2 1 
ATOM   2092  N N   . LEU A 1 270 ? 54.812  26.424  55.928  1.00 64.48  ? 345  LEU A N   1 
ATOM   2093  C CA  . LEU A 1 270 ? 54.795  25.424  56.990  1.00 59.89  ? 345  LEU A CA  1 
ATOM   2094  C C   . LEU A 1 270 ? 56.178  25.273  57.617  1.00 52.54  ? 345  LEU A C   1 
ATOM   2095  O O   . LEU A 1 270 ? 56.303  25.089  58.839  1.00 49.85  ? 345  LEU A O   1 
ATOM   2096  C CB  . LEU A 1 270 ? 54.302  24.088  56.429  1.00 54.12  ? 345  LEU A CB  1 
ATOM   2097  C CG  . LEU A 1 270 ? 54.562  22.798  57.209  1.00 50.13  ? 345  LEU A CG  1 
ATOM   2098  C CD1 . LEU A 1 270 ? 54.040  22.915  58.625  1.00 47.76  ? 345  LEU A CD1 1 
ATOM   2099  C CD2 . LEU A 1 270 ? 53.946  21.595  56.509  1.00 54.48  ? 345  LEU A CD2 1 
ATOM   2100  N N   . LYS A 1 271 ? 57.229  25.339  56.794  1.00 49.34  ? 346  LYS A N   1 
ATOM   2101  C CA  . LYS A 1 271 ? 58.581  25.272  57.339  1.00 55.12  ? 346  LYS A CA  1 
ATOM   2102  C C   . LYS A 1 271 ? 58.813  26.401  58.338  1.00 61.53  ? 346  LYS A C   1 
ATOM   2103  O O   . LYS A 1 271 ? 59.318  26.181  59.452  1.00 66.14  ? 346  LYS A O   1 
ATOM   2104  C CB  . LYS A 1 271 ? 59.606  25.335  56.205  1.00 55.48  ? 346  LYS A CB  1 
ATOM   2105  C CG  . LYS A 1 271 ? 59.883  23.992  55.550  1.00 66.75  ? 346  LYS A CG  1 
ATOM   2106  C CD  . LYS A 1 271 ? 60.113  22.892  56.577  1.00 70.28  ? 346  LYS A CD  1 
ATOM   2107  C CE  . LYS A 1 271 ? 60.859  21.717  55.964  1.00 64.97  ? 346  LYS A CE  1 
ATOM   2108  N NZ  . LYS A 1 271 ? 60.156  21.150  54.781  1.00 62.55  ? 346  LYS A NZ  1 
ATOM   2109  N N   . CYS A 1 272 ? 58.433  27.622  57.948  1.00 52.80  ? 347  CYS A N   1 
ATOM   2110  C CA  . CYS A 1 272 ? 58.540  28.767  58.850  1.00 47.90  ? 347  CYS A CA  1 
ATOM   2111  C C   . CYS A 1 272 ? 57.781  28.521  60.152  1.00 56.29  ? 347  CYS A C   1 
ATOM   2112  O O   . CYS A 1 272 ? 58.299  28.782  61.249  1.00 63.82  ? 347  CYS A O   1 
ATOM   2113  C CB  . CYS A 1 272 ? 58.020  30.033  58.162  1.00 42.89  ? 347  CYS A CB  1 
ATOM   2114  S SG  . CYS A 1 272 ? 58.794  30.438  56.574  1.00 65.74  ? 347  CYS A SG  1 
ATOM   2115  N N   . LEU A 1 273 ? 56.546  28.019  60.048  1.00 55.61  ? 348  LEU A N   1 
ATOM   2116  C CA  . LEU A 1 273 ? 55.723  27.823  61.242  1.00 58.50  ? 348  LEU A CA  1 
ATOM   2117  C C   . LEU A 1 273 ? 56.357  26.829  62.208  1.00 55.10  ? 348  LEU A C   1 
ATOM   2118  O O   . LEU A 1 273 ? 56.369  27.055  63.425  1.00 58.56  ? 348  LEU A O   1 
ATOM   2119  C CB  . LEU A 1 273 ? 54.313  27.372  60.858  1.00 51.87  ? 348  LEU A CB  1 
ATOM   2120  C CG  . LEU A 1 273 ? 53.422  28.441  60.231  1.00 43.88  ? 348  LEU A CG  1 
ATOM   2121  C CD1 . LEU A 1 273 ? 52.010  27.926  60.056  1.00 46.75  ? 348  LEU A CD1 1 
ATOM   2122  C CD2 . LEU A 1 273 ? 53.430  29.667  61.125  1.00 43.53  ? 348  LEU A CD2 1 
ATOM   2123  N N   . THR A 1 274 ? 56.872  25.712  61.690  1.00 53.43  ? 349  THR A N   1 
ATOM   2124  C CA  . THR A 1 274 ? 57.496  24.726  62.571  1.00 59.91  ? 349  THR A CA  1 
ATOM   2125  C C   . THR A 1 274 ? 58.743  25.295  63.242  1.00 58.42  ? 349  THR A C   1 
ATOM   2126  O O   . THR A 1 274 ? 58.957  25.110  64.460  1.00 59.78  ? 349  THR A O   1 
ATOM   2127  C CB  . THR A 1 274 ? 57.834  23.462  61.781  1.00 48.52  ? 349  THR A CB  1 
ATOM   2128  O OG1 . THR A 1 274 ? 58.558  23.820  60.599  1.00 74.27  ? 349  THR A OG1 1 
ATOM   2129  C CG2 . THR A 1 274 ? 56.561  22.735  61.377  1.00 47.92  ? 349  THR A CG2 1 
ATOM   2130  N N   . ALA A 1 275 ? 59.580  25.988  62.460  1.00 47.32  ? 350  ALA A N   1 
ATOM   2131  C CA  . ALA A 1 275 ? 60.755  26.635  63.031  1.00 53.58  ? 350  ALA A CA  1 
ATOM   2132  C C   . ALA A 1 275 ? 60.363  27.546  64.188  1.00 60.91  ? 350  ALA A C   1 
ATOM   2133  O O   . ALA A 1 275 ? 61.006  27.541  65.244  1.00 60.67  ? 350  ALA A O   1 
ATOM   2134  C CB  . ALA A 1 275 ? 61.503  27.415  61.951  1.00 45.19  ? 350  ALA A CB  1 
ATOM   2135  N N   . LEU A 1 276 ? 59.288  28.320  64.016  1.00 54.57  ? 351  LEU A N   1 
ATOM   2136  C CA  . LEU A 1 276 ? 58.855  29.209  65.093  1.00 51.08  ? 351  LEU A CA  1 
ATOM   2137  C C   . LEU A 1 276 ? 58.325  28.427  66.293  1.00 55.86  ? 351  LEU A C   1 
ATOM   2138  O O   . LEU A 1 276 ? 58.547  28.824  67.448  1.00 59.72  ? 351  LEU A O   1 
ATOM   2139  C CB  . LEU A 1 276 ? 57.795  30.180  64.579  1.00 59.92  ? 351  LEU A CB  1 
ATOM   2140  C CG  . LEU A 1 276 ? 58.285  31.245  63.602  1.00 51.87  ? 351  LEU A CG  1 
ATOM   2141  C CD1 . LEU A 1 276 ? 57.113  32.060  63.098  1.00 63.28  ? 351  LEU A CD1 1 
ATOM   2142  C CD2 . LEU A 1 276 ? 59.307  32.136  64.281  1.00 57.69  ? 351  LEU A CD2 1 
ATOM   2143  N N   . GLN A 1 277 ? 57.604  27.330  66.033  1.00 56.99  ? 352  GLN A N   1 
ATOM   2144  C CA  . GLN A 1 277 ? 57.021  26.534  67.110  1.00 64.32  ? 352  GLN A CA  1 
ATOM   2145  C C   . GLN A 1 277 ? 58.084  26.046  68.078  1.00 69.49  ? 352  GLN A C   1 
ATOM   2146  O O   . GLN A 1 277 ? 57.856  26.012  69.293  1.00 68.32  ? 352  GLN A O   1 
ATOM   2147  C CB  . GLN A 1 277 ? 56.259  25.337  66.545  1.00 61.10  ? 352  GLN A CB  1 
ATOM   2148  C CG  . GLN A 1 277 ? 54.804  25.598  66.231  1.00 61.36  ? 352  GLN A CG  1 
ATOM   2149  C CD  . GLN A 1 277 ? 54.396  25.026  64.891  1.00 74.36  ? 352  GLN A CD  1 
ATOM   2150  O OE1 . GLN A 1 277 ? 54.821  23.933  64.512  1.00 67.91  ? 352  GLN A OE1 1 
ATOM   2151  N NE2 . GLN A 1 277 ? 53.556  25.757  64.168  1.00 95.72  ? 352  GLN A NE2 1 
ATOM   2152  N N   . GLY A 1 278 ? 59.235  25.632  67.556  1.00 65.30  ? 353  GLY A N   1 
ATOM   2153  C CA  . GLY A 1 278 ? 60.312  25.242  68.460  1.00 65.71  ? 353  GLY A CA  1 
ATOM   2154  C C   . GLY A 1 278 ? 60.628  26.302  69.510  1.00 62.99  ? 353  GLY A C   1 
ATOM   2155  O O   . GLY A 1 278 ? 60.530  26.067  70.729  1.00 79.84  ? 353  GLY A O   1 
ATOM   2156  N N   . LEU A 1 279 ? 60.981  27.495  69.028  1.00 56.94  ? 354  LEU A N   1 
ATOM   2157  C CA  . LEU A 1 279 ? 61.353  28.591  69.917  1.00 53.07  ? 354  LEU A CA  1 
ATOM   2158  C C   . LEU A 1 279 ? 60.230  28.934  70.888  1.00 64.34  ? 354  LEU A C   1 
ATOM   2159  O O   . LEU A 1 279 ? 60.476  29.150  72.080  1.00 71.83  ? 354  LEU A O   1 
ATOM   2160  C CB  . LEU A 1 279 ? 61.727  29.817  69.090  1.00 50.04  ? 354  LEU A CB  1 
ATOM   2161  C CG  . LEU A 1 279 ? 62.555  29.503  67.848  1.00 51.97  ? 354  LEU A CG  1 
ATOM   2162  C CD1 . LEU A 1 279 ? 62.541  30.685  66.888  1.00 56.25  ? 354  LEU A CD1 1 
ATOM   2163  C CD2 . LEU A 1 279 ? 63.972  29.117  68.236  1.00 40.68  ? 354  LEU A CD2 1 
ATOM   2164  N N   . TYR A 1 280 ? 58.986  28.985  70.401  1.00 58.33  ? 355  TYR A N   1 
ATOM   2165  C CA  . TYR A 1 280 ? 57.891  29.361  71.292  1.00 59.47  ? 355  TYR A CA  1 
ATOM   2166  C C   . TYR A 1 280 ? 57.597  28.275  72.317  1.00 65.47  ? 355  TYR A C   1 
ATOM   2167  O O   . TYR A 1 280 ? 57.093  28.574  73.407  1.00 62.04  ? 355  TYR A O   1 
ATOM   2168  C CB  . TYR A 1 280 ? 56.641  29.699  70.489  1.00 58.34  ? 355  TYR A CB  1 
ATOM   2169  C CG  . TYR A 1 280 ? 56.743  31.047  69.828  1.00 61.43  ? 355  TYR A CG  1 
ATOM   2170  C CD1 . TYR A 1 280 ? 56.640  32.216  70.570  1.00 64.77  ? 355  TYR A CD1 1 
ATOM   2171  C CD2 . TYR A 1 280 ? 56.976  31.153  68.468  1.00 63.45  ? 355  TYR A CD2 1 
ATOM   2172  C CE1 . TYR A 1 280 ? 56.748  33.451  69.967  1.00 54.08  ? 355  TYR A CE1 1 
ATOM   2173  C CE2 . TYR A 1 280 ? 57.086  32.378  67.857  1.00 67.42  ? 355  TYR A CE2 1 
ATOM   2174  C CZ  . TYR A 1 280 ? 56.971  33.526  68.609  1.00 61.78  ? 355  TYR A CZ  1 
ATOM   2175  O OH  . TYR A 1 280 ? 57.084  34.747  67.988  1.00 64.42  ? 355  TYR A OH  1 
ATOM   2176  N N   . TYR A 1 281 ? 57.903  27.017  71.993  1.00 67.65  ? 356  TYR A N   1 
ATOM   2177  C CA  . TYR A 1 281 ? 57.827  25.961  72.993  1.00 66.11  ? 356  TYR A CA  1 
ATOM   2178  C C   . TYR A 1 281 ? 58.874  26.158  74.080  1.00 70.81  ? 356  TYR A C   1 
ATOM   2179  O O   . TYR A 1 281 ? 58.609  25.885  75.256  1.00 67.00  ? 356  TYR A O   1 
ATOM   2180  C CB  . TYR A 1 281 ? 58.000  24.595  72.327  1.00 63.93  ? 356  TYR A CB  1 
ATOM   2181  C CG  . TYR A 1 281 ? 57.539  23.428  73.171  1.00 85.57  ? 356  TYR A CG  1 
ATOM   2182  C CD1 . TYR A 1 281 ? 56.269  23.410  73.739  1.00 95.56  ? 356  TYR A CD1 1 
ATOM   2183  C CD2 . TYR A 1 281 ? 58.377  22.347  73.409  1.00 82.36  ? 356  TYR A CD2 1 
ATOM   2184  C CE1 . TYR A 1 281 ? 55.843  22.338  74.510  1.00 102.24 ? 356  TYR A CE1 1 
ATOM   2185  C CE2 . TYR A 1 281 ? 57.963  21.275  74.179  1.00 96.72  ? 356  TYR A CE2 1 
ATOM   2186  C CZ  . TYR A 1 281 ? 56.695  21.275  74.729  1.00 112.23 ? 356  TYR A CZ  1 
ATOM   2187  O OH  . TYR A 1 281 ? 56.279  20.209  75.497  1.00 111.83 ? 356  TYR A OH  1 
ATOM   2188  N N   . ASN A 1 282 ? 60.067  26.643  73.713  1.00 76.02  ? 357  ASN A N   1 
ATOM   2189  C CA  . ASN A 1 282 ? 61.136  26.732  74.716  1.00 78.00  ? 357  ASN A CA  1 
ATOM   2190  C C   . ASN A 1 282 ? 60.863  27.721  75.852  1.00 84.27  ? 357  ASN A C   1 
ATOM   2191  O O   . ASN A 1 282 ? 61.590  27.686  76.851  1.00 95.02  ? 357  ASN A O   1 
ATOM   2192  C CB  . ASN A 1 282 ? 62.473  27.083  74.062  1.00 78.72  ? 357  ASN A CB  1 
ATOM   2193  C CG  . ASN A 1 282 ? 63.651  26.537  74.843  1.00 85.52  ? 357  ASN A CG  1 
ATOM   2194  O OD1 . ASN A 1 282 ? 63.480  25.843  75.849  1.00 79.21  ? 357  ASN A OD1 1 
ATOM   2195  N ND2 . ASN A 1 282 ? 64.856  26.842  74.383  1.00 124.78 ? 357  ASN A ND2 1 
ATOM   2196  N N   . LYS A 1 283 ? 59.857  28.589  75.736  1.00 67.67  ? 358  LYS A N   1 
ATOM   2197  C CA  . LYS A 1 283 ? 59.528  29.574  76.777  1.00 79.35  ? 358  LYS A CA  1 
ATOM   2198  C C   . LYS A 1 283 ? 60.737  30.432  77.154  1.00 97.76  ? 358  LYS A C   1 
ATOM   2199  O O   . LYS A 1 283 ? 61.074  30.594  78.330  1.00 84.17  ? 358  LYS A O   1 
ATOM   2200  C CB  . LYS A 1 283 ? 58.938  28.906  78.027  1.00 51.95  ? 358  LYS A CB  1 
ATOM   2201  C CG  . LYS A 1 283 ? 57.575  28.252  77.845  1.00 81.98  ? 358  LYS A CG  1 
ATOM   2202  C CD  . LYS A 1 283 ? 57.068  27.690  79.170  1.00 82.08  ? 358  LYS A CD  1 
ATOM   2203  C CE  . LYS A 1 283 ? 55.871  28.473  79.692  1.00 86.25  ? 358  LYS A CE  1 
ATOM   2204  N NZ  . LYS A 1 283 ? 55.117  27.724  80.737  1.00 86.74  ? 358  LYS A NZ  1 
ATOM   2205  N N   . GLU A 1 284 ? 61.392  31.003  76.142  1.00 106.93 ? 359  GLU A N   1 
ATOM   2206  C CA  . GLU A 1 284 ? 62.368  32.047  76.426  1.00 94.14  ? 359  GLU A CA  1 
ATOM   2207  C C   . GLU A 1 284 ? 61.716  33.419  76.487  1.00 109.13 ? 359  GLU A C   1 
ATOM   2208  O O   . GLU A 1 284 ? 62.191  34.298  77.218  1.00 128.47 ? 359  GLU A O   1 
ATOM   2209  C CB  . GLU A 1 284 ? 63.480  32.083  75.377  1.00 84.27  ? 359  GLU A CB  1 
ATOM   2210  C CG  . GLU A 1 284 ? 64.127  30.757  75.028  1.00 79.96  ? 359  GLU A CG  1 
ATOM   2211  C CD  . GLU A 1 284 ? 63.690  30.258  73.669  1.00 90.91  ? 359  GLU A CD  1 
ATOM   2212  O OE1 . GLU A 1 284 ? 62.739  30.839  73.107  1.00 95.75  ? 359  GLU A OE1 1 
ATOM   2213  O OE2 . GLU A 1 284 ? 64.307  29.300  73.157  1.00 107.24 ? 359  GLU A OE2 1 
ATOM   2214  N N   . LEU A 1 285 ? 60.645  33.620  75.714  1.00 89.47  ? 360  LEU A N   1 
ATOM   2215  C CA  . LEU A 1 285 ? 59.857  34.848  75.707  1.00 91.50  ? 360  LEU A CA  1 
ATOM   2216  C C   . LEU A 1 285 ? 60.689  36.058  75.299  1.00 100.22 ? 360  LEU A C   1 
ATOM   2217  O O   . LEU A 1 285 ? 60.568  36.548  74.171  1.00 102.95 ? 360  LEU A O   1 
ATOM   2218  C CB  . LEU A 1 285 ? 59.212  35.089  77.074  1.00 94.73  ? 360  LEU A CB  1 
ATOM   2219  C CG  . LEU A 1 285 ? 58.176  34.064  77.538  1.00 97.72  ? 360  LEU A CG  1 
ATOM   2220  C CD1 . LEU A 1 285 ? 58.820  32.977  78.381  1.00 68.77  ? 360  LEU A CD1 1 
ATOM   2221  C CD2 . LEU A 1 285 ? 57.055  34.748  78.293  1.00 105.43 ? 360  LEU A CD2 1 
ATOM   2222  N N   . ASN A 1 286 ? 61.537  36.544  76.207  1.00 92.59  ? 361  ASN A N   1 
ATOM   2223  C CA  . ASN A 1 286 ? 62.292  37.765  75.949  1.00 79.08  ? 361  ASN A CA  1 
ATOM   2224  C C   . ASN A 1 286 ? 63.271  37.613  74.794  1.00 88.60  ? 361  ASN A C   1 
ATOM   2225  O O   . ASN A 1 286 ? 63.732  38.624  74.253  1.00 104.52 ? 361  ASN A O   1 
ATOM   2226  C CB  . ASN A 1 286 ? 63.055  38.184  77.208  1.00 92.88  ? 361  ASN A CB  1 
ATOM   2227  C CG  . ASN A 1 286 ? 63.592  36.996  77.976  1.00 118.06 ? 361  ASN A CG  1 
ATOM   2228  O OD1 . ASN A 1 286 ? 64.542  36.343  77.545  1.00 129.42 ? 361  ASN A OD1 1 
ATOM   2229  N ND2 . ASN A 1 286 ? 62.972  36.695  79.111  1.00 123.23 ? 361  ASN A ND2 1 
ATOM   2230  N N   . SER A 1 287 ? 63.595  36.380  74.405  1.00 101.82 ? 362  SER A N   1 
ATOM   2231  C CA  . SER A 1 287 ? 64.631  36.115  73.412  1.00 114.22 ? 362  SER A CA  1 
ATOM   2232  C C   . SER A 1 287 ? 64.244  36.646  72.039  1.00 105.12 ? 362  SER A C   1 
ATOM   2233  O O   . SER A 1 287 ? 64.073  35.866  71.095  1.00 113.73 ? 362  SER A O   1 
ATOM   2234  C CB  . SER A 1 287 ? 64.896  34.617  73.310  1.00 118.82 ? 362  SER A CB  1 
ATOM   2235  O OG  . SER A 1 287 ? 63.713  33.954  72.898  1.00 118.99 ? 362  SER A OG  1 
ATOM   2236  N N   . LYS A 1 288 ? 64.077  37.964  71.923  1.00 109.87 ? 363  LYS A N   1 
ATOM   2237  C CA  . LYS A 1 288 ? 63.705  38.623  70.675  1.00 111.17 ? 363  LYS A CA  1 
ATOM   2238  C C   . LYS A 1 288 ? 62.326  38.171  70.204  1.00 104.06 ? 363  LYS A C   1 
ATOM   2239  O O   . LYS A 1 288 ? 61.809  38.687  69.207  1.00 107.36 ? 363  LYS A O   1 
ATOM   2240  C CB  . LYS A 1 288 ? 64.754  38.364  69.586  1.00 116.66 ? 363  LYS A CB  1 
ATOM   2241  C CG  . LYS A 1 288 ? 66.166  38.766  69.984  1.00 129.20 ? 363  LYS A CG  1 
ATOM   2242  C CD  . LYS A 1 288 ? 66.363  40.271  70.020  1.00 133.09 ? 363  LYS A CD  1 
ATOM   2243  C CE  . LYS A 1 288 ? 67.752  40.635  69.520  1.00 127.47 ? 363  LYS A CE  1 
ATOM   2244  N NZ  . LYS A 1 288 ? 68.811  39.797  70.162  1.00 122.68 ? 363  LYS A NZ  1 
ATOM   2245  N N   . LEU A 1 289 ? 61.717  37.218  70.921  1.00 81.71  ? 364  LEU A N   1 
ATOM   2246  C CA  . LEU A 1 289 ? 60.401  36.715  70.544  1.00 81.04  ? 364  LEU A CA  1 
ATOM   2247  C C   . LEU A 1 289 ? 59.308  37.732  70.824  1.00 81.97  ? 364  LEU A C   1 
ATOM   2248  O O   . LEU A 1 289 ? 58.253  37.683  70.190  1.00 81.95  ? 364  LEU A O   1 
ATOM   2249  C CB  . LEU A 1 289 ? 60.088  35.409  71.277  1.00 82.86  ? 364  LEU A CB  1 
ATOM   2250  C CG  . LEU A 1 289 ? 60.833  34.131  70.890  1.00 64.23  ? 364  LEU A CG  1 
ATOM   2251  C CD1 . LEU A 1 289 ? 60.259  32.933  71.634  1.00 71.93  ? 364  LEU A CD1 1 
ATOM   2252  C CD2 . LEU A 1 289 ? 60.756  33.913  69.395  1.00 49.61  ? 364  LEU A CD2 1 
ATOM   2253  N N   . GLU A 1 290 ? 59.527  38.646  71.773  1.00 75.61  ? 365  GLU A N   1 
ATOM   2254  C CA  . GLU A 1 290 ? 58.553  39.707  72.002  1.00 73.40  ? 365  GLU A CA  1 
ATOM   2255  C C   . GLU A 1 290 ? 58.418  40.585  70.764  1.00 71.61  ? 365  GLU A C   1 
ATOM   2256  O O   . GLU A 1 290 ? 57.306  40.841  70.278  1.00 88.19  ? 365  GLU A O   1 
ATOM   2257  C CB  . GLU A 1 290 ? 58.958  40.546  73.216  1.00 67.89  ? 365  GLU A CB  1 
ATOM   2258  C CG  . GLU A 1 290 ? 58.351  40.090  74.538  1.00 77.52  ? 365  GLU A CG  1 
ATOM   2259  C CD  . GLU A 1 290 ? 59.363  40.072  75.667  1.00 87.76  ? 365  GLU A CD  1 
ATOM   2260  O OE1 . GLU A 1 290 ? 60.328  40.865  75.609  1.00 85.14  ? 365  GLU A OE1 1 
ATOM   2261  O OE2 . GLU A 1 290 ? 59.188  39.277  76.614  1.00 99.37  ? 365  GLU A OE2 1 
ATOM   2262  N N   . LEU A 1 291 ? 59.552  41.045  70.231  1.00 61.93  ? 366  LEU A N   1 
ATOM   2263  C CA  . LEU A 1 291 ? 59.534  41.890  69.043  1.00 64.27  ? 366  LEU A CA  1 
ATOM   2264  C C   . LEU A 1 291 ? 58.966  41.142  67.843  1.00 71.25  ? 366  LEU A C   1 
ATOM   2265  O O   . LEU A 1 291 ? 58.171  41.699  67.076  1.00 66.67  ? 366  LEU A O   1 
ATOM   2266  C CB  . LEU A 1 291 ? 60.947  42.398  68.751  1.00 75.27  ? 366  LEU A CB  1 
ATOM   2267  C CG  . LEU A 1 291 ? 61.272  43.829  69.186  1.00 61.93  ? 366  LEU A CG  1 
ATOM   2268  C CD1 . LEU A 1 291 ? 60.855  44.043  70.626  1.00 61.92  ? 366  LEU A CD1 1 
ATOM   2269  C CD2 . LEU A 1 291 ? 62.758  44.107  69.025  1.00 83.31  ? 366  LEU A CD2 1 
ATOM   2270  N N   . PHE A 1 292 ? 59.348  39.872  67.679  1.00 72.88  ? 367  PHE A N   1 
ATOM   2271  C CA  . PHE A 1 292 ? 58.839  39.077  66.564  1.00 72.34  ? 367  PHE A CA  1 
ATOM   2272  C C   . PHE A 1 292 ? 57.335  38.859  66.675  1.00 68.89  ? 367  PHE A C   1 
ATOM   2273  O O   . PHE A 1 292 ? 56.616  38.935  65.671  1.00 72.81  ? 367  PHE A O   1 
ATOM   2274  C CB  . PHE A 1 292 ? 59.571  37.737  66.497  1.00 66.18  ? 367  PHE A CB  1 
ATOM   2275  C CG  . PHE A 1 292 ? 59.287  36.953  65.247  1.00 54.62  ? 367  PHE A CG  1 
ATOM   2276  C CD1 . PHE A 1 292 ? 58.190  36.109  65.178  1.00 47.76  ? 367  PHE A CD1 1 
ATOM   2277  C CD2 . PHE A 1 292 ? 60.109  37.066  64.136  1.00 59.31  ? 367  PHE A CD2 1 
ATOM   2278  C CE1 . PHE A 1 292 ? 57.920  35.388  64.031  1.00 54.47  ? 367  PHE A CE1 1 
ATOM   2279  C CE2 . PHE A 1 292 ? 59.842  36.345  62.983  1.00 59.01  ? 367  PHE A CE2 1 
ATOM   2280  C CZ  . PHE A 1 292 ? 58.747  35.505  62.932  1.00 59.20  ? 367  PHE A CZ  1 
ATOM   2281  N N   . THR A 1 293 ? 56.845  38.563  67.882  1.00 62.46  ? 368  THR A N   1 
ATOM   2282  C CA  . THR A 1 293 ? 55.407  38.433  68.088  1.00 61.84  ? 368  THR A CA  1 
ATOM   2283  C C   . THR A 1 293 ? 54.687  39.720  67.722  1.00 70.35  ? 368  THR A C   1 
ATOM   2284  O O   . THR A 1 293 ? 53.717  39.698  66.963  1.00 86.33  ? 368  THR A O   1 
ATOM   2285  C CB  . THR A 1 293 ? 55.092  38.044  69.535  1.00 54.87  ? 368  THR A CB  1 
ATOM   2286  O OG1 . THR A 1 293 ? 55.770  38.931  70.433  1.00 96.49  ? 368  THR A OG1 1 
ATOM   2287  C CG2 . THR A 1 293 ? 55.481  36.605  69.819  1.00 50.34  ? 368  THR A CG2 1 
ATOM   2288  N N   . SER A 1 294 ? 55.147  40.856  68.247  1.00 64.10  ? 369  SER A N   1 
ATOM   2289  C CA  . SER A 1 294 ? 54.463  42.108  67.939  1.00 58.01  ? 369  SER A CA  1 
ATOM   2290  C C   . SER A 1 294 ? 54.493  42.402  66.441  1.00 61.24  ? 369  SER A C   1 
ATOM   2291  O O   . SER A 1 294 ? 53.520  42.927  65.885  1.00 69.05  ? 369  SER A O   1 
ATOM   2292  C CB  . SER A 1 294 ? 55.074  43.257  68.740  1.00 71.63  ? 369  SER A CB  1 
ATOM   2293  O OG  . SER A 1 294 ? 56.483  43.142  68.822  1.00 100.55 ? 369  SER A OG  1 
ATOM   2294  N N   . ARG A 1 295 ? 55.582  42.029  65.762  1.00 58.05  ? 370  ARG A N   1 
ATOM   2295  C CA  . ARG A 1 295 ? 55.726  42.354  64.345  1.00 63.94  ? 370  ARG A CA  1 
ATOM   2296  C C   . ARG A 1 295 ? 54.876  41.446  63.456  1.00 67.25  ? 370  ARG A C   1 
ATOM   2297  O O   . ARG A 1 295 ? 54.317  41.908  62.454  1.00 72.28  ? 370  ARG A O   1 
ATOM   2298  C CB  . ARG A 1 295 ? 57.200  42.269  63.951  1.00 69.52  ? 370  ARG A CB  1 
ATOM   2299  C CG  . ARG A 1 295 ? 57.526  42.613  62.505  1.00 74.28  ? 370  ARG A CG  1 
ATOM   2300  C CD  . ARG A 1 295 ? 57.231  44.059  62.117  1.00 74.76  ? 370  ARG A CD  1 
ATOM   2301  N NE  . ARG A 1 295 ? 57.623  44.329  60.736  1.00 88.76  ? 370  ARG A NE  1 
ATOM   2302  C CZ  . ARG A 1 295 ? 57.169  43.678  59.669  1.00 116.99 ? 370  ARG A CZ  1 
ATOM   2303  N NH1 . ARG A 1 295 ? 56.198  42.781  59.760  1.00 115.51 ? 370  ARG A NH1 1 
ATOM   2304  N NH2 . ARG A 1 295 ? 57.690  43.948  58.475  1.00 128.65 ? 370  ARG A NH2 1 
ATOM   2305  N N   . PHE A 1 296 ? 54.764  40.154  63.794  1.00 69.13  ? 371  PHE A N   1 
ATOM   2306  C CA  . PHE A 1 296 ? 54.162  39.172  62.892  1.00 64.95  ? 371  PHE A CA  1 
ATOM   2307  C C   . PHE A 1 296 ? 52.955  38.449  63.502  1.00 67.14  ? 371  PHE A C   1 
ATOM   2308  O O   . PHE A 1 296 ? 52.531  37.399  62.987  1.00 73.23  ? 371  PHE A O   1 
ATOM   2309  C CB  . PHE A 1 296 ? 55.220  38.162  62.446  1.00 58.20  ? 371  PHE A CB  1 
ATOM   2310  C CG  . PHE A 1 296 ? 56.400  38.782  61.737  1.00 64.45  ? 371  PHE A CG  1 
ATOM   2311  C CD1 . PHE A 1 296 ? 56.306  39.163  60.406  1.00 65.51  ? 371  PHE A CD1 1 
ATOM   2312  C CD2 . PHE A 1 296 ? 57.611  38.955  62.392  1.00 61.09  ? 371  PHE A CD2 1 
ATOM   2313  C CE1 . PHE A 1 296 ? 57.387  39.722  59.749  1.00 60.64  ? 371  PHE A CE1 1 
ATOM   2314  C CE2 . PHE A 1 296 ? 58.697  39.508  61.738  1.00 58.51  ? 371  PHE A CE2 1 
ATOM   2315  C CZ  . PHE A 1 296 ? 58.583  39.895  60.416  1.00 59.69  ? 371  PHE A CZ  1 
ATOM   2316  N N   . LYS A 1 297 ? 52.382  38.998  64.577  1.00 59.31  ? 372  LYS A N   1 
ATOM   2317  C CA  . LYS A 1 297 ? 51.204  38.404  65.198  1.00 69.73  ? 372  LYS A CA  1 
ATOM   2318  C C   . LYS A 1 297 ? 50.047  38.327  64.220  1.00 74.19  ? 372  LYS A C   1 
ATOM   2319  O O   . LYS A 1 297 ? 49.369  37.297  64.117  1.00 77.96  ? 372  LYS A O   1 
ATOM   2320  C CB  . LYS A 1 297 ? 50.800  39.227  66.422  1.00 69.84  ? 372  LYS A CB  1 
ATOM   2321  C CG  . LYS A 1 297 ? 50.095  38.447  67.511  1.00 68.55  ? 372  LYS A CG  1 
ATOM   2322  C CD  . LYS A 1 297 ? 48.822  39.162  67.942  1.00 94.53  ? 372  LYS A CD  1 
ATOM   2323  C CE  . LYS A 1 297 ? 49.100  40.569  68.450  1.00 99.07  ? 372  LYS A CE  1 
ATOM   2324  N NZ  . LYS A 1 297 ? 47.998  41.050  69.333  1.00 107.30 ? 372  LYS A NZ  1 
ATOM   2325  N N   . ASP A 1 298 ? 49.789  39.429  63.518  1.00 76.54  ? 373  ASP A N   1 
ATOM   2326  C CA  . ASP A 1 298 ? 48.674  39.467  62.586  1.00 85.79  ? 373  ASP A CA  1 
ATOM   2327  C C   . ASP A 1 298 ? 48.889  38.482  61.450  1.00 71.98  ? 373  ASP A C   1 
ATOM   2328  O O   . ASP A 1 298 ? 47.935  37.864  60.965  1.00 72.25  ? 373  ASP A O   1 
ATOM   2329  C CB  . ASP A 1 298 ? 48.498  40.887  62.054  1.00 98.71  ? 373  ASP A CB  1 
ATOM   2330  C CG  . ASP A 1 298 ? 48.238  41.890  63.161  1.00 113.90 ? 373  ASP A CG  1 
ATOM   2331  O OD1 . ASP A 1 298 ? 47.988  41.459  64.309  1.00 105.27 ? 373  ASP A OD1 1 
ATOM   2332  O OD2 . ASP A 1 298 ? 48.295  43.107  62.889  1.00 125.47 ? 373  ASP A OD2 1 
ATOM   2333  N N   . ARG A 1 299 ? 50.144  38.303  61.030  1.00 54.83  ? 374  ARG A N   1 
ATOM   2334  C CA  . ARG A 1 299 ? 50.446  37.313  60.003  1.00 55.22  ? 374  ARG A CA  1 
ATOM   2335  C C   . ARG A 1 299 ? 50.129  35.901  60.479  1.00 64.39  ? 374  ARG A C   1 
ATOM   2336  O O   . ARG A 1 299 ? 49.561  35.102  59.729  1.00 68.50  ? 374  ARG A O   1 
ATOM   2337  C CB  . ARG A 1 299 ? 51.911  37.408  59.586  1.00 58.92  ? 374  ARG A CB  1 
ATOM   2338  C CG  . ARG A 1 299 ? 52.230  36.681  58.285  1.00 57.78  ? 374  ARG A CG  1 
ATOM   2339  C CD  . ARG A 1 299 ? 51.185  36.888  57.193  1.00 55.02  ? 374  ARG A CD  1 
ATOM   2340  N NE  . ARG A 1 299 ? 51.426  35.969  56.089  1.00 66.45  ? 374  ARG A NE  1 
ATOM   2341  C CZ  . ARG A 1 299 ? 50.646  34.938  55.792  1.00 69.20  ? 374  ARG A CZ  1 
ATOM   2342  N NH1 . ARG A 1 299 ? 49.444  34.803  56.329  1.00 68.10  ? 374  ARG A NH1 1 
ATOM   2343  N NH2 . ARG A 1 299 ? 51.080  34.023  54.932  1.00 65.03  ? 374  ARG A NH2 1 
ATOM   2344  N N   . ILE A 1 300 ? 50.503  35.566  61.715  1.00 64.81  ? 375  ILE A N   1 
ATOM   2345  C CA  . ILE A 1 300 ? 50.199  34.225  62.225  1.00 65.89  ? 375  ILE A CA  1 
ATOM   2346  C C   . ILE A 1 300 ? 48.686  34.026  62.331  1.00 66.98  ? 375  ILE A C   1 
ATOM   2347  O O   . ILE A 1 300 ? 48.133  32.988  61.920  1.00 66.77  ? 375  ILE A O   1 
ATOM   2348  C CB  . ILE A 1 300 ? 50.900  33.991  63.575  1.00 61.25  ? 375  ILE A CB  1 
ATOM   2349  C CG1 . ILE A 1 300 ? 52.404  34.209  63.424  1.00 56.45  ? 375  ILE A CG1 1 
ATOM   2350  C CG2 . ILE A 1 300 ? 50.636  32.581  64.075  1.00 65.97  ? 375  ILE A CG2 1 
ATOM   2351  C CD1 . ILE A 1 300 ? 53.112  34.497  64.720  1.00 55.58  ? 375  ILE A CD1 1 
ATOM   2352  N N   . VAL A 1 301 ? 47.994  35.026  62.883  1.00 70.97  ? 376  VAL A N   1 
ATOM   2353  C CA  . VAL A 1 301 ? 46.542  34.948  63.015  1.00 62.05  ? 376  VAL A CA  1 
ATOM   2354  C C   . VAL A 1 301 ? 45.894  34.769  61.649  1.00 60.99  ? 376  VAL A C   1 
ATOM   2355  O O   . VAL A 1 301 ? 44.933  34.007  61.496  1.00 73.52  ? 376  VAL A O   1 
ATOM   2356  C CB  . VAL A 1 301 ? 46.004  36.192  63.745  1.00 56.83  ? 376  VAL A CB  1 
ATOM   2357  C CG1 . VAL A 1 301 ? 44.488  36.188  63.754  1.00 62.85  ? 376  VAL A CG1 1 
ATOM   2358  C CG2 . VAL A 1 301 ? 46.542  36.239  65.163  1.00 60.07  ? 376  VAL A CG2 1 
ATOM   2359  N N   . SER A 1 302 ? 46.417  35.454  60.630  1.00 48.22  ? 377  SER A N   1 
ATOM   2360  C CA  . SER A 1 302 ? 45.889  35.298  59.281  1.00 66.89  ? 377  SER A CA  1 
ATOM   2361  C C   . SER A 1 302 ? 46.206  33.923  58.708  1.00 60.16  ? 377  SER A C   1 
ATOM   2362  O O   . SER A 1 302 ? 45.402  33.368  57.950  1.00 63.95  ? 377  SER A O   1 
ATOM   2363  C CB  . SER A 1 302 ? 46.450  36.392  58.375  1.00 68.83  ? 377  SER A CB  1 
ATOM   2364  O OG  . SER A 1 302 ? 47.745  36.046  57.912  1.00 71.16  ? 377  SER A OG  1 
ATOM   2365  N N   . MET A 1 303 ? 47.373  33.371  59.043  1.00 70.59  ? 378  MET A N   1 
ATOM   2366  C CA  . MET A 1 303 ? 47.728  32.026  58.613  1.00 71.38  ? 378  MET A CA  1 
ATOM   2367  C C   . MET A 1 303 ? 46.808  30.971  59.202  1.00 62.84  ? 378  MET A C   1 
ATOM   2368  O O   . MET A 1 303 ? 46.713  29.872  58.647  1.00 58.58  ? 378  MET A O   1 
ATOM   2369  C CB  . MET A 1 303 ? 49.182  31.729  58.983  1.00 62.70  ? 378  MET A CB  1 
ATOM   2370  C CG  . MET A 1 303 ? 50.171  32.349  58.027  1.00 57.00  ? 378  MET A CG  1 
ATOM   2371  S SD  . MET A 1 303 ? 51.841  31.710  58.168  1.00 65.99  ? 378  MET A SD  1 
ATOM   2372  C CE  . MET A 1 303 ? 52.402  32.703  59.543  1.00 66.69  ? 378  MET A CE  1 
ATOM   2373  N N   . THR A 1 304 ? 46.141  31.276  60.317  1.00 55.81  ? 379  THR A N   1 
ATOM   2374  C CA  . THR A 1 304 ? 45.087  30.369  60.778  1.00 64.24  ? 379  THR A CA  1 
ATOM   2375  C C   . THR A 1 304 ? 44.028  30.103  59.705  1.00 63.00  ? 379  THR A C   1 
ATOM   2376  O O   . THR A 1 304 ? 43.337  29.080  59.775  1.00 66.25  ? 379  THR A O   1 
ATOM   2377  C CB  . THR A 1 304 ? 44.392  30.905  62.030  1.00 56.95  ? 379  THR A CB  1 
ATOM   2378  O OG1 . THR A 1 304 ? 43.660  32.092  61.702  1.00 67.09  ? 379  THR A OG1 1 
ATOM   2379  C CG2 . THR A 1 304 ? 45.404  31.204  63.120  1.00 61.37  ? 379  THR A CG2 1 
ATOM   2380  N N   . LEU A 1 305 ? 43.870  30.998  58.727  1.00 63.00  ? 380  LEU A N   1 
ATOM   2381  C CA  . LEU A 1 305 ? 42.951  30.807  57.606  1.00 62.12  ? 380  LEU A CA  1 
ATOM   2382  C C   . LEU A 1 305 ? 43.708  30.696  56.283  1.00 64.38  ? 380  LEU A C   1 
ATOM   2383  O O   . LEU A 1 305 ? 43.284  31.225  55.253  1.00 60.46  ? 380  LEU A O   1 
ATOM   2384  C CB  . LEU A 1 305 ? 41.923  31.934  57.540  1.00 65.45  ? 380  LEU A CB  1 
ATOM   2385  C CG  . LEU A 1 305 ? 40.583  31.670  58.234  1.00 64.14  ? 380  LEU A CG  1 
ATOM   2386  C CD1 . LEU A 1 305 ? 39.666  32.880  58.135  1.00 82.04  ? 380  LEU A CD1 1 
ATOM   2387  C CD2 . LEU A 1 305 ? 39.908  30.438  57.647  1.00 67.00  ? 380  LEU A CD2 1 
ATOM   2388  N N   . ASP A 1 306 ? 44.838  29.994  56.310  1.00 69.45  ? 381  ASP A N   1 
ATOM   2389  C CA  . ASP A 1 306 ? 45.686  29.840  55.138  1.00 64.86  ? 381  ASP A CA  1 
ATOM   2390  C C   . ASP A 1 306 ? 45.001  28.972  54.086  1.00 59.52  ? 381  ASP A C   1 
ATOM   2391  O O   . ASP A 1 306 ? 44.163  28.123  54.401  1.00 68.01  ? 381  ASP A O   1 
ATOM   2392  C CB  . ASP A 1 306 ? 47.025  29.222  55.553  1.00 67.28  ? 381  ASP A CB  1 
ATOM   2393  C CG  . ASP A 1 306 ? 48.091  29.349  54.486  1.00 66.97  ? 381  ASP A CG  1 
ATOM   2394  O OD1 . ASP A 1 306 ? 48.752  30.407  54.432  1.00 63.70  ? 381  ASP A OD1 1 
ATOM   2395  O OD2 . ASP A 1 306 ? 48.280  28.386  53.715  1.00 71.12  ? 381  ASP A OD2 1 
ATOM   2396  N N   . LYS A 1 307 ? 45.361  29.201  52.818  1.00 60.76  ? 382  LYS A N   1 
ATOM   2397  C CA  . LYS A 1 307 ? 44.861  28.357  51.734  1.00 66.60  ? 382  LYS A CA  1 
ATOM   2398  C C   . LYS A 1 307 ? 45.161  26.883  51.974  1.00 74.98  ? 382  LYS A C   1 
ATOM   2399  O O   . LYS A 1 307 ? 44.403  26.013  51.527  1.00 89.22  ? 382  LYS A O   1 
ATOM   2400  C CB  . LYS A 1 307 ? 45.463  28.798  50.396  1.00 68.08  ? 382  LYS A CB  1 
ATOM   2401  C CG  . LYS A 1 307 ? 44.717  29.910  49.673  1.00 70.02  ? 382  LYS A CG  1 
ATOM   2402  C CD  . LYS A 1 307 ? 43.402  29.395  49.106  1.00 105.36 ? 382  LYS A CD  1 
ATOM   2403  C CE  . LYS A 1 307 ? 42.954  30.198  47.890  1.00 108.71 ? 382  LYS A CE  1 
ATOM   2404  N NZ  . LYS A 1 307 ? 42.629  31.616  48.207  1.00 99.26  ? 382  LYS A NZ  1 
ATOM   2405  N N   . GLU A 1 308 ? 46.255  26.580  52.668  1.00 72.27  ? 383  GLU A N   1 
ATOM   2406  C CA  . GLU A 1 308 ? 46.641  25.208  52.974  1.00 73.22  ? 383  GLU A CA  1 
ATOM   2407  C C   . GLU A 1 308 ? 46.190  24.874  54.390  1.00 70.99  ? 383  GLU A C   1 
ATOM   2408  O O   . GLU A 1 308 ? 46.558  25.571  55.343  1.00 67.69  ? 383  GLU A O   1 
ATOM   2409  C CB  . GLU A 1 308 ? 48.151  25.028  52.828  1.00 78.84  ? 383  GLU A CB  1 
ATOM   2410  C CG  . GLU A 1 308 ? 48.693  25.559  51.515  1.00 89.92  ? 383  GLU A CG  1 
ATOM   2411  C CD  . GLU A 1 308 ? 48.036  24.913  50.314  1.00 95.86  ? 383  GLU A CD  1 
ATOM   2412  O OE1 . GLU A 1 308 ? 48.170  23.682  50.155  1.00 110.52 ? 383  GLU A OE1 1 
ATOM   2413  O OE2 . GLU A 1 308 ? 47.376  25.636  49.537  1.00 78.20  ? 383  GLU A OE2 1 
ATOM   2414  N N   . TYR A 1 309 ? 45.397  23.807  54.524  1.00 59.28  ? 384  TYR A N   1 
ATOM   2415  C CA  . TYR A 1 309 ? 44.809  23.477  55.820  1.00 63.43  ? 384  TYR A CA  1 
ATOM   2416  C C   . TYR A 1 309 ? 45.869  23.071  56.836  1.00 66.46  ? 384  TYR A C   1 
ATOM   2417  O O   . TYR A 1 309 ? 45.779  23.445  58.011  1.00 58.65  ? 384  TYR A O   1 
ATOM   2418  C CB  . TYR A 1 309 ? 43.770  22.369  55.659  1.00 66.88  ? 384  TYR A CB  1 
ATOM   2419  C CG  . TYR A 1 309 ? 42.370  22.880  55.407  1.00 72.87  ? 384  TYR A CG  1 
ATOM   2420  C CD1 . TYR A 1 309 ? 41.858  23.942  56.139  1.00 77.38  ? 384  TYR A CD1 1 
ATOM   2421  C CD2 . TYR A 1 309 ? 41.559  22.297  54.444  1.00 74.93  ? 384  TYR A CD2 1 
ATOM   2422  C CE1 . TYR A 1 309 ? 40.580  24.413  55.917  1.00 85.79  ? 384  TYR A CE1 1 
ATOM   2423  C CE2 . TYR A 1 309 ? 40.279  22.761  54.214  1.00 75.82  ? 384  TYR A CE2 1 
ATOM   2424  C CZ  . TYR A 1 309 ? 39.794  23.819  54.953  1.00 81.39  ? 384  TYR A CZ  1 
ATOM   2425  O OH  . TYR A 1 309 ? 38.519  24.282  54.725  1.00 83.31  ? 384  TYR A OH  1 
ATOM   2426  N N   . ASP A 1 310 ? 46.869  22.295  56.411  1.00 62.66  ? 385  ASP A N   1 
ATOM   2427  C CA  . ASP A 1 310 ? 47.935  21.892  57.325  1.00 63.73  ? 385  ASP A CA  1 
ATOM   2428  C C   . ASP A 1 310 ? 48.689  23.103  57.867  1.00 67.76  ? 385  ASP A C   1 
ATOM   2429  O O   . ASP A 1 310 ? 48.979  23.182  59.072  1.00 66.52  ? 385  ASP A O   1 
ATOM   2430  C CB  . ASP A 1 310 ? 48.877  20.919  56.614  1.00 66.57  ? 385  ASP A CB  1 
ATOM   2431  C CG  . ASP A 1 310 ? 49.231  21.373  55.207  1.00 84.26  ? 385  ASP A CG  1 
ATOM   2432  O OD1 . ASP A 1 310 ? 48.335  21.342  54.334  1.00 97.50  ? 385  ASP A OD1 1 
ATOM   2433  O OD2 . ASP A 1 310 ? 50.400  21.743  54.965  1.00 86.02  ? 385  ASP A OD2 1 
ATOM   2434  N N   . VAL A 1 311 ? 49.001  24.065  56.992  1.00 58.58  ? 386  VAL A N   1 
ATOM   2435  C CA  . VAL A 1 311 ? 49.605  25.319  57.434  1.00 52.18  ? 386  VAL A CA  1 
ATOM   2436  C C   . VAL A 1 311 ? 48.712  26.010  58.457  1.00 65.57  ? 386  VAL A C   1 
ATOM   2437  O O   . VAL A 1 311 ? 49.194  26.568  59.450  1.00 54.73  ? 386  VAL A O   1 
ATOM   2438  C CB  . VAL A 1 311 ? 49.886  26.227  56.223  1.00 42.90  ? 386  VAL A CB  1 
ATOM   2439  C CG1 . VAL A 1 311 ? 50.498  27.541  56.668  1.00 55.01  ? 386  VAL A CG1 1 
ATOM   2440  C CG2 . VAL A 1 311 ? 50.799  25.523  55.239  1.00 57.80  ? 386  VAL A CG2 1 
ATOM   2441  N N   . ALA A 1 312 ? 47.396  25.974  58.237  1.00 65.83  ? 387  ALA A N   1 
ATOM   2442  C CA  . ALA A 1 312 ? 46.472  26.639  59.151  1.00 55.00  ? 387  ALA A CA  1 
ATOM   2443  C C   . ALA A 1 312 ? 46.464  25.969  60.520  1.00 59.65  ? 387  ALA A C   1 
ATOM   2444  O O   . ALA A 1 312 ? 46.432  26.652  61.553  1.00 60.59  ? 387  ALA A O   1 
ATOM   2445  C CB  . ALA A 1 312 ? 45.069  26.656  58.548  1.00 59.81  ? 387  ALA A CB  1 
ATOM   2446  N N   . VAL A 1 313 ? 46.484  24.635  60.547  1.00 51.36  ? 388  VAL A N   1 
ATOM   2447  C CA  . VAL A 1 313 ? 46.548  23.919  61.819  1.00 58.70  ? 388  VAL A CA  1 
ATOM   2448  C C   . VAL A 1 313 ? 47.827  24.280  62.561  1.00 71.17  ? 388  VAL A C   1 
ATOM   2449  O O   . VAL A 1 313 ? 47.814  24.519  63.777  1.00 67.62  ? 388  VAL A O   1 
ATOM   2450  C CB  . VAL A 1 313 ? 46.440  22.399  61.592  1.00 48.03  ? 388  VAL A CB  1 
ATOM   2451  C CG1 . VAL A 1 313 ? 46.428  21.665  62.925  1.00 53.87  ? 388  VAL A CG1 1 
ATOM   2452  C CG2 . VAL A 1 313 ? 45.201  22.061  60.791  1.00 55.16  ? 388  VAL A CG2 1 
ATOM   2453  N N   . GLN A 1 314 ? 48.951  24.330  61.841  1.00 68.25  ? 389  GLN A N   1 
ATOM   2454  C CA  . GLN A 1 314 ? 50.207  24.700  62.488  1.00 62.82  ? 389  GLN A CA  1 
ATOM   2455  C C   . GLN A 1 314 ? 50.165  26.131  63.014  1.00 70.69  ? 389  GLN A C   1 
ATOM   2456  O O   . GLN A 1 314 ? 50.713  26.419  64.083  1.00 73.27  ? 389  GLN A O   1 
ATOM   2457  C CB  . GLN A 1 314 ? 51.378  24.504  61.529  1.00 61.69  ? 389  GLN A CB  1 
ATOM   2458  C CG  . GLN A 1 314 ? 51.667  23.044  61.240  1.00 70.64  ? 389  GLN A CG  1 
ATOM   2459  C CD  . GLN A 1 314 ? 51.497  22.175  62.472  1.00 74.06  ? 389  GLN A CD  1 
ATOM   2460  O OE1 . GLN A 1 314 ? 52.268  22.275  63.429  1.00 73.78  ? 389  GLN A OE1 1 
ATOM   2461  N NE2 . GLN A 1 314 ? 50.490  21.309  62.452  1.00 60.81  ? 389  GLN A NE2 1 
ATOM   2462  N N   . ALA A 1 315 ? 49.507  27.037  62.288  1.00 56.49  ? 390  ALA A N   1 
ATOM   2463  C CA  . ALA A 1 315 ? 49.395  28.416  62.759  1.00 52.36  ? 390  ALA A CA  1 
ATOM   2464  C C   . ALA A 1 315 ? 48.547  28.501  64.023  1.00 69.30  ? 390  ALA A C   1 
ATOM   2465  O O   . ALA A 1 315 ? 48.876  29.250  64.952  1.00 69.17  ? 390  ALA A O   1 
ATOM   2466  C CB  . ALA A 1 315 ? 48.810  29.302  61.661  1.00 47.55  ? 390  ALA A CB  1 
ATOM   2467  N N   . ILE A 1 316 ? 47.450  27.743  64.076  1.00 66.01  ? 391  ILE A N   1 
ATOM   2468  C CA  . ILE A 1 316 ? 46.632  27.713  65.287  1.00 59.97  ? 391  ILE A CA  1 
ATOM   2469  C C   . ILE A 1 316 ? 47.436  27.165  66.459  1.00 65.14  ? 391  ILE A C   1 
ATOM   2470  O O   . ILE A 1 316 ? 47.369  27.691  67.578  1.00 67.82  ? 391  ILE A O   1 
ATOM   2471  C CB  . ILE A 1 316 ? 45.348  26.898  65.051  1.00 61.08  ? 391  ILE A CB  1 
ATOM   2472  C CG1 . ILE A 1 316 ? 44.537  27.501  63.905  1.00 60.58  ? 391  ILE A CG1 1 
ATOM   2473  C CG2 . ILE A 1 316 ? 44.513  26.839  66.317  1.00 63.99  ? 391  ILE A CG2 1 
ATOM   2474  C CD1 . ILE A 1 316 ? 43.616  26.511  63.232  1.00 70.42  ? 391  ILE A CD1 1 
ATOM   2475  N N   . LYS A 1 317 ? 48.211  26.103  66.223  1.00 67.41  ? 392  LYS A N   1 
ATOM   2476  C CA  . LYS A 1 317 ? 49.025  25.533  67.292  1.00 74.80  ? 392  LYS A CA  1 
ATOM   2477  C C   . LYS A 1 317 ? 50.080  26.528  67.764  1.00 71.62  ? 392  LYS A C   1 
ATOM   2478  O O   . LYS A 1 317 ? 50.353  26.644  68.968  1.00 63.44  ? 392  LYS A O   1 
ATOM   2479  C CB  . LYS A 1 317 ? 49.670  24.236  66.806  1.00 71.65  ? 392  LYS A CB  1 
ATOM   2480  C CG  . LYS A 1 317 ? 48.667  23.119  66.557  1.00 55.83  ? 392  LYS A CG  1 
ATOM   2481  C CD  . LYS A 1 317 ? 49.224  22.090  65.586  1.00 81.47  ? 392  LYS A CD  1 
ATOM   2482  C CE  . LYS A 1 317 ? 49.941  20.956  66.301  1.00 90.31  ? 392  LYS A CE  1 
ATOM   2483  N NZ  . LYS A 1 317 ? 49.147  20.431  67.446  1.00 87.98  ? 392  LYS A NZ  1 
ATOM   2484  N N   . LEU A 1 318 ? 50.672  27.268  66.825  1.00 61.03  ? 393  LEU A N   1 
ATOM   2485  C CA  . LEU A 1 318 ? 51.614  28.322  67.183  1.00 64.86  ? 393  LEU A CA  1 
ATOM   2486  C C   . LEU A 1 318 ? 50.944  29.396  68.030  1.00 69.69  ? 393  LEU A C   1 
ATOM   2487  O O   . LEU A 1 318 ? 51.548  29.924  68.971  1.00 68.99  ? 393  LEU A O   1 
ATOM   2488  C CB  . LEU A 1 318 ? 52.208  28.936  65.917  1.00 59.32  ? 393  LEU A CB  1 
ATOM   2489  C CG  . LEU A 1 318 ? 53.409  29.862  66.099  1.00 58.57  ? 393  LEU A CG  1 
ATOM   2490  C CD1 . LEU A 1 318 ? 54.379  29.284  67.118  1.00 59.15  ? 393  LEU A CD1 1 
ATOM   2491  C CD2 . LEU A 1 318 ? 54.101  30.130  64.768  1.00 57.60  ? 393  LEU A CD2 1 
ATOM   2492  N N   . LEU A 1 319 ? 49.699  29.746  67.700  1.00 71.31  ? 394  LEU A N   1 
ATOM   2493  C CA  . LEU A 1 319 ? 48.984  30.735  68.501  1.00 71.59  ? 394  LEU A CA  1 
ATOM   2494  C C   . LEU A 1 319 ? 48.707  30.215  69.906  1.00 71.24  ? 394  LEU A C   1 
ATOM   2495  O O   . LEU A 1 319 ? 48.777  30.975  70.879  1.00 77.98  ? 394  LEU A O   1 
ATOM   2496  C CB  . LEU A 1 319 ? 47.686  31.144  67.808  1.00 68.30  ? 394  LEU A CB  1 
ATOM   2497  C CG  . LEU A 1 319 ? 47.871  32.120  66.648  1.00 56.64  ? 394  LEU A CG  1 
ATOM   2498  C CD1 . LEU A 1 319 ? 46.530  32.653  66.196  1.00 63.64  ? 394  LEU A CD1 1 
ATOM   2499  C CD2 . LEU A 1 319 ? 48.771  33.258  67.080  1.00 53.06  ? 394  LEU A CD2 1 
ATOM   2500  N N   . THR A 1 320 ? 48.396  28.922  70.037  1.00 67.44  ? 395  THR A N   1 
ATOM   2501  C CA  . THR A 1 320 ? 48.263  28.340  71.373  1.00 75.99  ? 395  THR A CA  1 
ATOM   2502  C C   . THR A 1 320 ? 49.575  28.424  72.144  1.00 87.06  ? 395  THR A C   1 
ATOM   2503  O O   . THR A 1 320 ? 49.579  28.684  73.353  1.00 92.53  ? 395  THR A O   1 
ATOM   2504  C CB  . THR A 1 320 ? 47.802  26.882  71.302  1.00 74.67  ? 395  THR A CB  1 
ATOM   2505  O OG1 . THR A 1 320 ? 48.899  26.048  70.907  1.00 100.70 ? 395  THR A OG1 1 
ATOM   2506  C CG2 . THR A 1 320 ? 46.642  26.711  70.341  1.00 56.48  ? 395  THR A CG2 1 
ATOM   2507  N N   . LEU A 1 321 ? 50.700  28.192  71.464  1.00 85.56  ? 396  LEU A N   1 
ATOM   2508  C CA  . LEU A 1 321 ? 51.997  28.316  72.128  1.00 81.11  ? 396  LEU A CA  1 
ATOM   2509  C C   . LEU A 1 321 ? 52.234  29.747  72.602  1.00 89.49  ? 396  LEU A C   1 
ATOM   2510  O O   . LEU A 1 321 ? 52.670  29.978  73.739  1.00 89.98  ? 396  LEU A O   1 
ATOM   2511  C CB  . LEU A 1 321 ? 53.116  27.865  71.190  1.00 64.23  ? 396  LEU A CB  1 
ATOM   2512  C CG  . LEU A 1 321 ? 53.328  26.358  71.064  1.00 57.49  ? 396  LEU A CG  1 
ATOM   2513  C CD1 . LEU A 1 321 ? 54.256  26.049  69.901  1.00 47.59  ? 396  LEU A CD1 1 
ATOM   2514  C CD2 . LEU A 1 321 ? 53.887  25.804  72.363  1.00 69.48  ? 396  LEU A CD2 1 
ATOM   2515  N N   . VAL A 1 322 ? 51.953  30.722  71.734  1.00 85.84  ? 397  VAL A N   1 
ATOM   2516  C CA  . VAL A 1 322 ? 52.079  32.128  72.110  1.00 73.65  ? 397  VAL A CA  1 
ATOM   2517  C C   . VAL A 1 322 ? 51.200  32.432  73.317  1.00 81.80  ? 397  VAL A C   1 
ATOM   2518  O O   . VAL A 1 322 ? 51.589  33.187  74.216  1.00 99.88  ? 397  VAL A O   1 
ATOM   2519  C CB  . VAL A 1 322 ? 51.731  33.032  70.913  1.00 52.27  ? 397  VAL A CB  1 
ATOM   2520  C CG1 . VAL A 1 322 ? 51.680  34.489  71.337  1.00 50.66  ? 397  VAL A CG1 1 
ATOM   2521  C CG2 . VAL A 1 322 ? 52.732  32.837  69.788  1.00 65.25  ? 397  VAL A CG2 1 
ATOM   2522  N N   . LEU A 1 323 ? 50.003  31.842  73.355  1.00 85.07  ? 398  LEU A N   1 
ATOM   2523  C CA  . LEU A 1 323 ? 49.118  32.015  74.503  1.00 96.64  ? 398  LEU A CA  1 
ATOM   2524  C C   . LEU A 1 323 ? 49.745  31.450  75.771  1.00 99.60  ? 398  LEU A C   1 
ATOM   2525  O O   . LEU A 1 323 ? 49.654  32.058  76.844  1.00 105.07 ? 398  LEU A O   1 
ATOM   2526  C CB  . LEU A 1 323 ? 47.771  31.349  74.219  1.00 81.80  ? 398  LEU A CB  1 
ATOM   2527  C CG  . LEU A 1 323 ? 46.631  31.584  75.208  1.00 89.01  ? 398  LEU A CG  1 
ATOM   2528  C CD1 . LEU A 1 323 ? 45.726  32.689  74.699  1.00 106.66 ? 398  LEU A CD1 1 
ATOM   2529  C CD2 . LEU A 1 323 ? 45.847  30.300  75.418  1.00 95.68  ? 398  LEU A CD2 1 
ATOM   2530  N N   . GLN A 1 324 ? 50.379  30.279  75.670  1.00 94.44  ? 399  GLN A N   1 
ATOM   2531  C CA  . GLN A 1 324 ? 51.077  29.735  76.834  1.00 101.09 ? 399  GLN A CA  1 
ATOM   2532  C C   . GLN A 1 324 ? 52.225  30.635  77.273  1.00 100.58 ? 399  GLN A C   1 
ATOM   2533  O O   . GLN A 1 324 ? 52.571  30.662  78.460  1.00 102.07 ? 399  GLN A O   1 
ATOM   2534  C CB  . GLN A 1 324 ? 51.607  28.325  76.565  1.00 106.71 ? 399  GLN A CB  1 
ATOM   2535  C CG  . GLN A 1 324 ? 50.571  27.207  76.618  1.00 98.06  ? 399  GLN A CG  1 
ATOM   2536  C CD  . GLN A 1 324 ? 50.187  26.698  75.244  1.00 110.26 ? 399  GLN A CD  1 
ATOM   2537  O OE1 . GLN A 1 324 ? 51.047  26.378  74.426  1.00 108.40 ? 399  GLN A OE1 1 
ATOM   2538  N NE2 . GLN A 1 324 ? 48.884  26.612  74.986  1.00 111.89 ? 399  GLN A NE2 1 
ATOM   2539  N N   . SER A 1 325 ? 52.831  31.372  76.341  1.00 105.82 ? 400  SER A N   1 
ATOM   2540  C CA  . SER A 1 325 ? 53.945  32.239  76.715  1.00 104.46 ? 400  SER A CA  1 
ATOM   2541  C C   . SER A 1 325 ? 53.466  33.439  77.527  1.00 103.91 ? 400  SER A C   1 
ATOM   2542  O O   . SER A 1 325 ? 53.977  33.700  78.622  1.00 102.46 ? 400  SER A O   1 
ATOM   2543  C CB  . SER A 1 325 ? 54.704  32.698  75.469  1.00 105.07 ? 400  SER A CB  1 
ATOM   2544  O OG  . SER A 1 325 ? 54.165  33.900  74.955  1.00 99.33  ? 400  SER A OG  1 
ATOM   2545  N N   . SER A 1 326 ? 52.481  34.181  77.014  1.00 104.57 ? 401  SER A N   1 
ATOM   2546  C CA  . SER A 1 326 ? 52.052  35.410  77.672  1.00 106.57 ? 401  SER A CA  1 
ATOM   2547  C C   . SER A 1 326 ? 50.536  35.534  77.787  1.00 108.42 ? 401  SER A C   1 
ATOM   2548  O O   . SER A 1 326 ? 50.047  36.190  78.709  1.00 114.13 ? 401  SER A O   1 
ATOM   2549  C CB  . SER A 1 326 ? 52.616  36.631  76.928  1.00 120.01 ? 401  SER A CB  1 
ATOM   2550  O OG  . SER A 1 326 ? 52.464  37.815  77.696  1.00 124.16 ? 401  SER A OG  1 
ATOM   2551  N N   . GLU A 1 327 ? 49.792  34.922  76.858  1.00 112.88 ? 402  GLU A N   1 
ATOM   2552  C CA  . GLU A 1 327 ? 48.328  34.960  76.812  1.00 132.93 ? 402  GLU A CA  1 
ATOM   2553  C C   . GLU A 1 327 ? 47.783  36.327  76.410  1.00 127.12 ? 402  GLU A C   1 
ATOM   2554  O O   . GLU A 1 327 ? 47.153  36.459  75.355  1.00 119.98 ? 402  GLU A O   1 
ATOM   2555  C CB  . GLU A 1 327 ? 47.706  34.541  78.150  1.00 129.80 ? 402  GLU A CB  1 
ATOM   2556  C CG  . GLU A 1 327 ? 46.191  34.383  78.095  1.00 120.53 ? 402  GLU A CG  1 
ATOM   2557  C CD  . GLU A 1 327 ? 45.718  33.063  78.671  1.00 127.33 ? 402  GLU A CD  1 
ATOM   2558  O OE1 . GLU A 1 327 ? 46.557  32.157  78.853  1.00 121.99 ? 402  GLU A OE1 1 
ATOM   2559  O OE2 . GLU A 1 327 ? 44.505  32.930  78.938  1.00 139.03 ? 402  GLU A OE2 1 
ATOM   2560  N N   . GLU A 1 328 ? 48.001  37.351  77.241  1.00 123.05 ? 403  GLU A N   1 
ATOM   2561  C CA  . GLU A 1 328 ? 47.410  38.657  76.964  1.00 128.04 ? 403  GLU A CA  1 
ATOM   2562  C C   . GLU A 1 328 ? 47.944  39.289  75.685  1.00 120.05 ? 403  GLU A C   1 
ATOM   2563  O O   . GLU A 1 328 ? 47.329  40.233  75.171  1.00 118.06 ? 403  GLU A O   1 
ATOM   2564  C CB  . GLU A 1 328 ? 47.649  39.605  78.137  1.00 113.16 ? 403  GLU A CB  1 
ATOM   2565  C CG  . GLU A 1 328 ? 49.086  40.064  78.291  1.00 115.34 ? 403  GLU A CG  1 
ATOM   2566  C CD  . GLU A 1 328 ? 49.873  39.224  79.279  1.00 121.58 ? 403  GLU A CD  1 
ATOM   2567  O OE1 . GLU A 1 328 ? 51.112  39.378  79.337  1.00 110.32 ? 403  GLU A OE1 1 
ATOM   2568  O OE2 . GLU A 1 328 ? 49.253  38.423  80.005  1.00 138.02 ? 403  GLU A OE2 1 
ATOM   2569  N N   . VAL A 1 329 ? 49.067  38.781  75.162  1.00 102.82 ? 404  VAL A N   1 
ATOM   2570  C CA  . VAL A 1 329 ? 49.696  39.351  73.972  1.00 94.33  ? 404  VAL A CA  1 
ATOM   2571  C C   . VAL A 1 329 ? 48.805  39.166  72.750  1.00 104.26 ? 404  VAL A C   1 
ATOM   2572  O O   . VAL A 1 329 ? 48.793  40.007  71.841  1.00 97.07  ? 404  VAL A O   1 
ATOM   2573  C CB  . VAL A 1 329 ? 51.083  38.713  73.752  1.00 91.03  ? 404  VAL A CB  1 
ATOM   2574  C CG1 . VAL A 1 329 ? 50.976  37.214  73.741  1.00 75.17  ? 404  VAL A CG1 1 
ATOM   2575  C CG2 . VAL A 1 329 ? 51.696  39.194  72.458  1.00 104.22 ? 404  VAL A CG2 1 
ATOM   2576  N N   . LEU A 1 330 ? 48.025  38.084  72.723  1.00 113.35 ? 405  LEU A N   1 
ATOM   2577  C CA  . LEU A 1 330 ? 47.245  37.716  71.551  1.00 106.98 ? 405  LEU A CA  1 
ATOM   2578  C C   . LEU A 1 330 ? 46.047  38.632  71.304  1.00 107.82 ? 405  LEU A C   1 
ATOM   2579  O O   . LEU A 1 330 ? 45.502  38.608  70.197  1.00 103.85 ? 405  LEU A O   1 
ATOM   2580  C CB  . LEU A 1 330 ? 46.775  36.269  71.707  1.00 96.02  ? 405  LEU A CB  1 
ATOM   2581  C CG  . LEU A 1 330 ? 47.811  35.205  71.341  1.00 82.97  ? 405  LEU A CG  1 
ATOM   2582  C CD1 . LEU A 1 330 ? 47.197  33.822  71.348  1.00 89.21  ? 405  LEU A CD1 1 
ATOM   2583  C CD2 . LEU A 1 330 ? 48.470  35.496  70.015  1.00 72.84  ? 405  LEU A CD2 1 
ATOM   2584  N N   . THR A 1 331 ? 45.624  39.422  72.299  1.00 104.55 ? 406  THR A N   1 
ATOM   2585  C CA  . THR A 1 331 ? 44.412  40.258  72.301  1.00 105.53 ? 406  THR A CA  1 
ATOM   2586  C C   . THR A 1 331 ? 43.127  39.491  71.984  1.00 117.39 ? 406  THR A C   1 
ATOM   2587  O O   . THR A 1 331 ? 43.161  38.421  71.375  1.00 124.39 ? 406  THR A O   1 
ATOM   2588  C CB  . THR A 1 331 ? 44.534  41.474  71.348  1.00 109.79 ? 406  THR A CB  1 
ATOM   2589  O OG1 . THR A 1 331 ? 43.474  42.391  71.653  1.00 132.68 ? 406  THR A OG1 1 
ATOM   2590  C CG2 . THR A 1 331 ? 44.374  41.082  69.882  1.00 99.75  ? 406  THR A CG2 1 
ATOM   2591  N N   . ALA A 1 332 ? 41.988  40.061  72.385  1.00 115.09 ? 407  ALA A N   1 
ATOM   2592  C CA  . ALA A 1 332 ? 40.716  39.346  72.315  1.00 98.73  ? 407  ALA A CA  1 
ATOM   2593  C C   . ALA A 1 332 ? 40.207  39.180  70.883  1.00 104.57 ? 407  ALA A C   1 
ATOM   2594  O O   . ALA A 1 332 ? 39.562  38.170  70.571  1.00 116.91 ? 407  ALA A O   1 
ATOM   2595  C CB  . ALA A 1 332 ? 39.668  40.064  73.168  1.00 92.04  ? 407  ALA A CB  1 
ATOM   2596  N N   . GLU A 1 333 ? 40.482  40.142  70.000  1.00 104.72 ? 408  GLU A N   1 
ATOM   2597  C CA  . GLU A 1 333 ? 39.999  40.041  68.623  1.00 122.34 ? 408  GLU A CA  1 
ATOM   2598  C C   . GLU A 1 333 ? 40.598  38.831  67.913  1.00 117.50 ? 408  GLU A C   1 
ATOM   2599  O O   . GLU A 1 333 ? 39.885  38.057  67.258  1.00 117.78 ? 408  GLU A O   1 
ATOM   2600  C CB  . GLU A 1 333 ? 40.318  41.330  67.860  1.00 126.26 ? 408  GLU A CB  1 
ATOM   2601  C CG  . GLU A 1 333 ? 39.175  42.342  67.800  1.00 126.59 ? 408  GLU A CG  1 
ATOM   2602  C CD  . GLU A 1 333 ? 39.309  43.445  68.832  1.00 137.99 ? 408  GLU A CD  1 
ATOM   2603  O OE1 . GLU A 1 333 ? 40.451  43.759  69.226  1.00 151.32 ? 408  GLU A OE1 1 
ATOM   2604  O OE2 . GLU A 1 333 ? 38.270  44.015  69.233  1.00 116.47 ? 408  GLU A OE2 1 
ATOM   2605  N N   . ASP A 1 334 ? 41.915  38.657  68.034  1.00 102.24 ? 409  ASP A N   1 
ATOM   2606  C CA  . ASP A 1 334 ? 42.586  37.529  67.401  1.00 88.03  ? 409  ASP A CA  1 
ATOM   2607  C C   . ASP A 1 334 ? 42.106  36.210  67.993  1.00 94.79  ? 409  ASP A C   1 
ATOM   2608  O O   . ASP A 1 334 ? 41.893  35.228  67.265  1.00 101.47 ? 409  ASP A O   1 
ATOM   2609  C CB  . ASP A 1 334 ? 44.095  37.684  67.574  1.00 94.75  ? 409  ASP A CB  1 
ATOM   2610  C CG  . ASP A 1 334 ? 44.648  38.885  66.825  1.00 112.83 ? 409  ASP A CG  1 
ATOM   2611  O OD1 . ASP A 1 334 ? 44.148  39.194  65.721  1.00 115.38 ? 409  ASP A OD1 1 
ATOM   2612  O OD2 . ASP A 1 334 ? 45.572  39.537  67.362  1.00 105.76 ? 409  ASP A OD2 1 
ATOM   2613  N N   . CYS A 1 335 ? 41.928  36.177  69.316  1.00 88.40  ? 410  CYS A N   1 
ATOM   2614  C CA  . CYS A 1 335 ? 41.369  34.998  69.966  1.00 95.73  ? 410  CYS A CA  1 
ATOM   2615  C C   . CYS A 1 335 ? 39.996  34.658  69.403  1.00 97.78  ? 410  CYS A C   1 
ATOM   2616  O O   . CYS A 1 335 ? 39.690  33.485  69.181  1.00 98.14  ? 410  CYS A O   1 
ATOM   2617  C CB  . CYS A 1 335 ? 41.290  35.212  71.478  1.00 88.72  ? 410  CYS A CB  1 
ATOM   2618  S SG  . CYS A 1 335 ? 42.890  35.333  72.299  1.00 102.17 ? 410  CYS A SG  1 
ATOM   2619  N N   . GLU A 1 336 ? 39.160  35.668  69.151  1.00 90.93  ? 411  GLU A N   1 
ATOM   2620  C CA  . GLU A 1 336 ? 37.838  35.410  68.584  1.00 83.66  ? 411  GLU A CA  1 
ATOM   2621  C C   . GLU A 1 336 ? 37.943  34.862  67.164  1.00 86.23  ? 411  GLU A C   1 
ATOM   2622  O O   . GLU A 1 336 ? 37.167  33.976  66.763  1.00 99.89  ? 411  GLU A O   1 
ATOM   2623  C CB  . GLU A 1 336 ? 37.008  36.693  68.614  1.00 92.01  ? 411  GLU A CB  1 
ATOM   2624  C CG  . GLU A 1 336 ? 35.561  36.525  68.198  1.00 111.98 ? 411  GLU A CG  1 
ATOM   2625  C CD  . GLU A 1 336 ? 35.046  37.712  67.407  1.00 125.09 ? 411  GLU A CD  1 
ATOM   2626  O OE1 . GLU A 1 336 ? 35.873  38.554  67.001  1.00 133.66 ? 411  GLU A OE1 1 
ATOM   2627  O OE2 . GLU A 1 336 ? 33.817  37.806  67.199  1.00 116.48 ? 411  GLU A OE2 1 
ATOM   2628  N N   . ASN A 1 337 ? 38.888  35.397  66.382  1.00 84.85  ? 412  ASN A N   1 
ATOM   2629  C CA  . ASN A 1 337 ? 39.181  34.818  65.073  1.00 88.13  ? 412  ASN A CA  1 
ATOM   2630  C C   . ASN A 1 337 ? 39.468  33.326  65.190  1.00 81.42  ? 412  ASN A C   1 
ATOM   2631  O O   . ASN A 1 337 ? 38.934  32.517  64.424  1.00 75.34  ? 412  ASN A O   1 
ATOM   2632  C CB  . ASN A 1 337 ? 40.363  35.536  64.416  1.00 90.78  ? 412  ASN A CB  1 
ATOM   2633  C CG  . ASN A 1 337 ? 40.166  37.033  64.332  1.00 104.64 ? 412  ASN A CG  1 
ATOM   2634  O OD1 . ASN A 1 337 ? 41.121  37.800  64.450  1.00 105.22 ? 412  ASN A OD1 1 
ATOM   2635  N ND2 . ASN A 1 337 ? 38.925  37.460  64.123  1.00 107.61 ? 412  ASN A ND2 1 
ATOM   2636  N N   . VAL A 1 338 ? 40.312  32.943  66.152  1.00 86.82  ? 413  VAL A N   1 
ATOM   2637  C CA  . VAL A 1 338 ? 40.588  31.516  66.342  1.00 81.42  ? 413  VAL A CA  1 
ATOM   2638  C C   . VAL A 1 338 ? 39.334  30.776  66.805  1.00 81.65  ? 413  VAL A C   1 
ATOM   2639  O O   . VAL A 1 338 ? 39.098  29.627  66.413  1.00 78.69  ? 413  VAL A O   1 
ATOM   2640  C CB  . VAL A 1 338 ? 41.762  31.294  67.315  1.00 68.45  ? 413  VAL A CB  1 
ATOM   2641  C CG1 . VAL A 1 338 ? 42.340  29.907  67.110  1.00 62.14  ? 413  VAL A CG1 1 
ATOM   2642  C CG2 . VAL A 1 338 ? 42.848  32.323  67.095  1.00 72.53  ? 413  VAL A CG2 1 
ATOM   2643  N N   . TYR A 1 339 ? 38.512  31.419  67.643  1.00 70.86  ? 414  TYR A N   1 
ATOM   2644  C CA  . TYR A 1 339 ? 37.307  30.768  68.155  1.00 75.10  ? 414  TYR A CA  1 
ATOM   2645  C C   . TYR A 1 339 ? 36.397  30.324  67.022  1.00 82.36  ? 414  TYR A C   1 
ATOM   2646  O O   . TYR A 1 339 ? 35.826  29.227  67.068  1.00 78.13  ? 414  TYR A O   1 
ATOM   2647  C CB  . TYR A 1 339 ? 36.522  31.703  69.074  1.00 75.21  ? 414  TYR A CB  1 
ATOM   2648  C CG  . TYR A 1 339 ? 37.226  32.163  70.321  1.00 79.00  ? 414  TYR A CG  1 
ATOM   2649  C CD1 . TYR A 1 339 ? 38.323  31.482  70.832  1.00 82.41  ? 414  TYR A CD1 1 
ATOM   2650  C CD2 . TYR A 1 339 ? 36.775  33.283  70.999  1.00 87.11  ? 414  TYR A CD2 1 
ATOM   2651  C CE1 . TYR A 1 339 ? 38.956  31.925  71.976  1.00 85.35  ? 414  TYR A CE1 1 
ATOM   2652  C CE2 . TYR A 1 339 ? 37.394  33.728  72.131  1.00 92.28  ? 414  TYR A CE2 1 
ATOM   2653  C CZ  . TYR A 1 339 ? 38.479  33.051  72.620  1.00 87.77  ? 414  TYR A CZ  1 
ATOM   2654  O OH  . TYR A 1 339 ? 39.075  33.522  73.760  1.00 104.79 ? 414  TYR A OH  1 
ATOM   2655  N N   . HIS A 1 340 ? 36.225  31.181  66.010  1.00 89.87  ? 415  HIS A N   1 
ATOM   2656  C CA  . HIS A 1 340 ? 35.333  30.833  64.902  1.00 85.66  ? 415  HIS A CA  1 
ATOM   2657  C C   . HIS A 1 340 ? 35.702  29.505  64.248  1.00 77.13  ? 415  HIS A C   1 
ATOM   2658  O O   . HIS A 1 340 ? 34.820  28.795  63.750  1.00 75.24  ? 415  HIS A O   1 
ATOM   2659  C CB  . HIS A 1 340 ? 35.320  31.931  63.836  1.00 85.73  ? 415  HIS A CB  1 
ATOM   2660  C CG  . HIS A 1 340 ? 35.037  33.297  64.371  1.00 92.71  ? 415  HIS A CG  1 
ATOM   2661  N ND1 . HIS A 1 340 ? 35.727  34.416  63.957  1.00 102.72 ? 415  HIS A ND1 1 
ATOM   2662  C CD2 . HIS A 1 340 ? 34.122  33.731  65.270  1.00 84.76  ? 415  HIS A CD2 1 
ATOM   2663  C CE1 . HIS A 1 340 ? 35.259  35.477  64.588  1.00 108.00 ? 415  HIS A CE1 1 
ATOM   2664  N NE2 . HIS A 1 340 ? 34.284  35.089  65.390  1.00 108.22 ? 415  HIS A NE2 1 
ATOM   2665  N N   . LEU A 1 341 ? 36.988  29.148  64.252  1.00 74.92  ? 416  LEU A N   1 
ATOM   2666  C CA  . LEU A 1 341 ? 37.465  27.972  63.532  1.00 66.61  ? 416  LEU A CA  1 
ATOM   2667  C C   . LEU A 1 341 ? 36.982  26.655  64.128  1.00 64.43  ? 416  LEU A C   1 
ATOM   2668  O O   . LEU A 1 341 ? 37.093  25.624  63.459  1.00 59.63  ? 416  LEU A O   1 
ATOM   2669  C CB  . LEU A 1 341 ? 38.992  27.986  63.483  1.00 55.55  ? 416  LEU A CB  1 
ATOM   2670  C CG  . LEU A 1 341 ? 39.593  29.245  62.861  1.00 59.04  ? 416  LEU A CG  1 
ATOM   2671  C CD1 . LEU A 1 341 ? 41.112  29.167  62.840  1.00 78.11  ? 416  LEU A CD1 1 
ATOM   2672  C CD2 . LEU A 1 341 ? 39.028  29.483  61.466  1.00 60.91  ? 416  LEU A CD2 1 
ATOM   2673  N N   . VAL A 1 342 ? 36.453  26.654  65.355  1.00 60.73  ? 417  VAL A N   1 
ATOM   2674  C CA  . VAL A 1 342 ? 35.935  25.415  65.924  1.00 65.06  ? 417  VAL A CA  1 
ATOM   2675  C C   . VAL A 1 342 ? 34.716  24.913  65.161  1.00 66.31  ? 417  VAL A C   1 
ATOM   2676  O O   . VAL A 1 342 ? 34.339  23.744  65.304  1.00 65.13  ? 417  VAL A O   1 
ATOM   2677  C CB  . VAL A 1 342 ? 35.592  25.584  67.417  1.00 61.90  ? 417  VAL A CB  1 
ATOM   2678  C CG1 . VAL A 1 342 ? 36.755  26.213  68.169  1.00 66.95  ? 417  VAL A CG1 1 
ATOM   2679  C CG2 . VAL A 1 342 ? 34.329  26.416  67.583  1.00 67.34  ? 417  VAL A CG2 1 
ATOM   2680  N N   . TYR A 1 343 ? 34.087  25.766  64.352  1.00 68.65  ? 418  TYR A N   1 
ATOM   2681  C CA  . TYR A 1 343 ? 32.956  25.380  63.521  1.00 63.98  ? 418  TYR A CA  1 
ATOM   2682  C C   . TYR A 1 343 ? 33.366  25.050  62.091  1.00 66.91  ? 418  TYR A C   1 
ATOM   2683  O O   . TYR A 1 343 ? 32.497  24.942  61.220  1.00 79.66  ? 418  TYR A O   1 
ATOM   2684  C CB  . TYR A 1 343 ? 31.898  26.488  63.511  1.00 55.50  ? 418  TYR A CB  1 
ATOM   2685  C CG  . TYR A 1 343 ? 31.394  26.886  64.881  1.00 61.20  ? 418  TYR A CG  1 
ATOM   2686  C CD1 . TYR A 1 343 ? 30.786  25.955  65.716  1.00 60.89  ? 418  TYR A CD1 1 
ATOM   2687  C CD2 . TYR A 1 343 ? 31.521  28.190  65.338  1.00 59.81  ? 418  TYR A CD2 1 
ATOM   2688  C CE1 . TYR A 1 343 ? 30.323  26.313  66.967  1.00 60.93  ? 418  TYR A CE1 1 
ATOM   2689  C CE2 . TYR A 1 343 ? 31.062  28.557  66.588  1.00 71.14  ? 418  TYR A CE2 1 
ATOM   2690  C CZ  . TYR A 1 343 ? 30.463  27.614  67.399  1.00 69.50  ? 418  TYR A CZ  1 
ATOM   2691  O OH  . TYR A 1 343 ? 30.005  27.975  68.645  1.00 80.21  ? 418  TYR A OH  1 
ATOM   2692  N N   . SER A 1 344 ? 34.660  24.888  61.830  1.00 53.39  ? 419  SER A N   1 
ATOM   2693  C CA  . SER A 1 344 ? 35.131  24.643  60.476  1.00 67.17  ? 419  SER A CA  1 
ATOM   2694  C C   . SER A 1 344 ? 34.874  23.199  60.066  1.00 68.24  ? 419  SER A C   1 
ATOM   2695  O O   . SER A 1 344 ? 34.792  22.296  60.904  1.00 59.01  ? 419  SER A O   1 
ATOM   2696  C CB  . SER A 1 344 ? 36.623  24.966  60.356  1.00 61.48  ? 419  SER A CB  1 
ATOM   2697  O OG  . SER A 1 344 ? 37.420  23.918  60.875  1.00 63.33  ? 419  SER A OG  1 
ATOM   2698  N N   . ALA A 1 345 ? 34.741  22.987  58.754  1.00 65.72  ? 420  ALA A N   1 
ATOM   2699  C CA  . ALA A 1 345 ? 34.515  21.636  58.253  1.00 65.49  ? 420  ALA A CA  1 
ATOM   2700  C C   . ALA A 1 345 ? 35.745  20.764  58.470  1.00 72.65  ? 420  ALA A C   1 
ATOM   2701  O O   . ALA A 1 345 ? 35.626  19.559  58.720  1.00 84.82  ? 420  ALA A O   1 
ATOM   2702  C CB  . ALA A 1 345 ? 34.130  21.675  56.773  1.00 76.15  ? 420  ALA A CB  1 
ATOM   2703  N N   . HIS A 1 346 ? 36.933  21.358  58.384  1.00 69.44  ? 421  HIS A N   1 
ATOM   2704  C CA  . HIS A 1 346 ? 38.188  20.633  58.555  1.00 58.80  ? 421  HIS A CA  1 
ATOM   2705  C C   . HIS A 1 346 ? 38.387  20.301  60.030  1.00 61.39  ? 421  HIS A C   1 
ATOM   2706  O O   . HIS A 1 346 ? 38.623  21.197  60.846  1.00 65.41  ? 421  HIS A O   1 
ATOM   2707  C CB  . HIS A 1 346 ? 39.339  21.480  58.023  1.00 61.77  ? 421  HIS A CB  1 
ATOM   2708  C CG  . HIS A 1 346 ? 40.590  20.706  57.756  1.00 68.43  ? 421  HIS A CG  1 
ATOM   2709  N ND1 . HIS A 1 346 ? 40.664  19.727  56.788  1.00 74.46  ? 421  HIS A ND1 1 
ATOM   2710  C CD2 . HIS A 1 346 ? 41.820  20.772  58.319  1.00 74.93  ? 421  HIS A CD2 1 
ATOM   2711  C CE1 . HIS A 1 346 ? 41.884  19.220  56.771  1.00 75.02  ? 421  HIS A CE1 1 
ATOM   2712  N NE2 . HIS A 1 346 ? 42.605  19.836  57.690  1.00 75.37  ? 421  HIS A NE2 1 
ATOM   2713  N N   . ARG A 1 347 ? 38.287  19.017  60.379  1.00 64.13  ? 422  ARG A N   1 
ATOM   2714  C CA  . ARG A 1 347 ? 38.402  18.637  61.785  1.00 55.34  ? 422  ARG A CA  1 
ATOM   2715  C C   . ARG A 1 347 ? 39.759  18.963  62.397  1.00 58.14  ? 422  ARG A C   1 
ATOM   2716  O O   . ARG A 1 347 ? 39.787  19.327  63.584  1.00 54.63  ? 422  ARG A O   1 
ATOM   2717  C CB  . ARG A 1 347 ? 38.079  17.149  61.980  1.00 46.80  ? 422  ARG A CB  1 
ATOM   2718  C CG  . ARG A 1 347 ? 37.867  16.804  63.454  1.00 55.16  ? 422  ARG A CG  1 
ATOM   2719  C CD  . ARG A 1 347 ? 37.582  15.333  63.702  1.00 73.73  ? 422  ARG A CD  1 
ATOM   2720  N NE  . ARG A 1 347 ? 37.111  15.104  65.065  1.00 69.63  ? 422  ARG A NE  1 
ATOM   2721  C CZ  . ARG A 1 347 ? 37.898  14.976  66.126  1.00 60.78  ? 422  ARG A CZ  1 
ATOM   2722  N NH1 . ARG A 1 347 ? 39.216  15.017  66.019  1.00 79.40  ? 422  ARG A NH1 1 
ATOM   2723  N NH2 . ARG A 1 347 ? 37.348  14.804  67.325  1.00 60.90  ? 422  ARG A NH2 1 
ATOM   2724  N N   . PRO A 1 348 ? 40.896  18.834  61.700  1.00 60.78  ? 423  PRO A N   1 
ATOM   2725  C CA  . PRO A 1 348 ? 42.161  19.265  62.328  1.00 50.11  ? 423  PRO A CA  1 
ATOM   2726  C C   . PRO A 1 348 ? 42.156  20.724  62.759  1.00 60.77  ? 423  PRO A C   1 
ATOM   2727  O O   . PRO A 1 348 ? 42.508  21.032  63.909  1.00 63.99  ? 423  PRO A O   1 
ATOM   2728  C CB  . PRO A 1 348 ? 43.189  18.985  61.228  1.00 52.66  ? 423  PRO A CB  1 
ATOM   2729  C CG  . PRO A 1 348 ? 42.633  17.801  60.529  1.00 47.03  ? 423  PRO A CG  1 
ATOM   2730  C CD  . PRO A 1 348 ? 41.151  18.055  60.472  1.00 57.00  ? 423  PRO A CD  1 
ATOM   2731  N N   . VAL A 1 349 ? 41.763  21.635  61.862  1.00 49.97  ? 424  VAL A N   1 
ATOM   2732  C CA  . VAL A 1 349 ? 41.664  23.050  62.217  1.00 53.38  ? 424  VAL A CA  1 
ATOM   2733  C C   . VAL A 1 349 ? 40.702  23.240  63.383  1.00 58.31  ? 424  VAL A C   1 
ATOM   2734  O O   . VAL A 1 349 ? 40.983  23.992  64.328  1.00 55.65  ? 424  VAL A O   1 
ATOM   2735  C CB  . VAL A 1 349 ? 41.237  23.880  60.990  1.00 47.41  ? 424  VAL A CB  1 
ATOM   2736  C CG1 . VAL A 1 349 ? 40.573  25.182  61.416  1.00 58.20  ? 424  VAL A CG1 1 
ATOM   2737  C CG2 . VAL A 1 349 ? 42.426  24.164  60.092  1.00 48.42  ? 424  VAL A CG2 1 
ATOM   2738  N N   . ALA A 1 350 ? 39.560  22.547  63.344  1.00 54.33  ? 425  ALA A N   1 
ATOM   2739  C CA  . ALA A 1 350 ? 38.540  22.730  64.371  1.00 53.60  ? 425  ALA A CA  1 
ATOM   2740  C C   . ALA A 1 350 ? 39.033  22.270  65.736  1.00 58.60  ? 425  ALA A C   1 
ATOM   2741  O O   . ALA A 1 350 ? 38.800  22.946  66.742  1.00 71.38  ? 425  ALA A O   1 
ATOM   2742  C CB  . ALA A 1 350 ? 37.262  21.987  63.982  1.00 59.48  ? 425  ALA A CB  1 
ATOM   2743  N N   . VAL A 1 351 ? 39.727  21.132  65.797  1.00 54.94  ? 426  VAL A N   1 
ATOM   2744  C CA  . VAL A 1 351 ? 40.180  20.638  67.092  1.00 58.67  ? 426  VAL A CA  1 
ATOM   2745  C C   . VAL A 1 351 ? 41.370  21.445  67.596  1.00 66.87  ? 426  VAL A C   1 
ATOM   2746  O O   . VAL A 1 351 ? 41.520  21.635  68.808  1.00 75.59  ? 426  VAL A O   1 
ATOM   2747  C CB  . VAL A 1 351 ? 40.503  19.134  67.035  1.00 46.96  ? 426  VAL A CB  1 
ATOM   2748  C CG1 . VAL A 1 351 ? 39.239  18.330  66.749  1.00 53.12  ? 426  VAL A CG1 1 
ATOM   2749  C CG2 . VAL A 1 351 ? 41.597  18.839  66.022  1.00 51.47  ? 426  VAL A CG2 1 
ATOM   2750  N N   . ALA A 1 352 ? 42.218  21.957  66.697  1.00 62.80  ? 427  ALA A N   1 
ATOM   2751  C CA  . ALA A 1 352 ? 43.280  22.853  67.143  1.00 67.70  ? 427  ALA A CA  1 
ATOM   2752  C C   . ALA A 1 352 ? 42.696  24.132  67.732  1.00 74.14  ? 427  ALA A C   1 
ATOM   2753  O O   . ALA A 1 352 ? 43.133  24.598  68.793  1.00 80.52  ? 427  ALA A O   1 
ATOM   2754  C CB  . ALA A 1 352 ? 44.226  23.168  65.985  1.00 56.30  ? 427  ALA A CB  1 
ATOM   2755  N N   . ALA A 1 353 ? 41.687  24.699  67.065  1.00 68.80  ? 428  ALA A N   1 
ATOM   2756  C CA  . ALA A 1 353 ? 41.023  25.888  67.585  1.00 57.41  ? 428  ALA A CA  1 
ATOM   2757  C C   . ALA A 1 353 ? 40.291  25.592  68.887  1.00 54.12  ? 428  ALA A C   1 
ATOM   2758  O O   . ALA A 1 353 ? 40.231  26.447  69.774  1.00 72.59  ? 428  ALA A O   1 
ATOM   2759  C CB  . ALA A 1 353 ? 40.056  26.444  66.543  1.00 58.30  ? 428  ALA A CB  1 
ATOM   2760  N N   . GLY A 1 354 ? 39.723  24.393  69.020  1.00 64.65  ? 429  GLY A N   1 
ATOM   2761  C CA  . GLY A 1 354 ? 39.055  24.038  70.261  1.00 71.90  ? 429  GLY A CA  1 
ATOM   2762  C C   . GLY A 1 354 ? 40.032  23.871  71.406  1.00 71.02  ? 429  GLY A C   1 
ATOM   2763  O O   . GLY A 1 354 ? 39.724  24.206  72.550  1.00 68.02  ? 429  GLY A O   1 
ATOM   2764  N N   . GLU A 1 355 ? 41.224  23.350  71.112  1.00 79.37  ? 430  GLU A N   1 
ATOM   2765  C CA  . GLU A 1 355 ? 42.293  23.313  72.103  1.00 84.77  ? 430  GLU A CA  1 
ATOM   2766  C C   . GLU A 1 355 ? 42.687  24.725  72.522  1.00 77.80  ? 430  GLU A C   1 
ATOM   2767  O O   . GLU A 1 355 ? 42.844  25.015  73.715  1.00 73.06  ? 430  GLU A O   1 
ATOM   2768  C CB  . GLU A 1 355 ? 43.491  22.555  71.528  1.00 86.58  ? 430  GLU A CB  1 
ATOM   2769  C CG  . GLU A 1 355 ? 44.810  22.803  72.232  1.00 108.49 ? 430  GLU A CG  1 
ATOM   2770  C CD  . GLU A 1 355 ? 45.865  21.783  71.847  1.00 119.09 ? 430  GLU A CD  1 
ATOM   2771  O OE1 . GLU A 1 355 ? 46.748  21.488  72.682  1.00 119.56 ? 430  GLU A OE1 1 
ATOM   2772  O OE2 . GLU A 1 355 ? 45.814  21.280  70.705  1.00 116.80 ? 430  GLU A OE2 1 
ATOM   2773  N N   . PHE A 1 356 ? 42.846  25.617  71.541  1.00 77.00  ? 431  PHE A N   1 
ATOM   2774  C CA  . PHE A 1 356 ? 43.144  27.015  71.838  1.00 69.24  ? 431  PHE A CA  1 
ATOM   2775  C C   . PHE A 1 356 ? 42.064  27.631  72.722  1.00 71.38  ? 431  PHE A C   1 
ATOM   2776  O O   . PHE A 1 356 ? 42.367  28.354  73.678  1.00 71.35  ? 431  PHE A O   1 
ATOM   2777  C CB  . PHE A 1 356 ? 43.282  27.799  70.531  1.00 67.53  ? 431  PHE A CB  1 
ATOM   2778  C CG  . PHE A 1 356 ? 43.456  29.277  70.721  1.00 76.41  ? 431  PHE A CG  1 
ATOM   2779  C CD1 . PHE A 1 356 ? 44.708  29.813  70.965  1.00 82.75  ? 431  PHE A CD1 1 
ATOM   2780  C CD2 . PHE A 1 356 ? 42.369  30.132  70.648  1.00 86.09  ? 431  PHE A CD2 1 
ATOM   2781  C CE1 . PHE A 1 356 ? 44.873  31.173  71.138  1.00 89.28  ? 431  PHE A CE1 1 
ATOM   2782  C CE2 . PHE A 1 356 ? 42.527  31.494  70.822  1.00 89.84  ? 431  PHE A CE2 1 
ATOM   2783  C CZ  . PHE A 1 356 ? 43.781  32.016  71.066  1.00 92.07  ? 431  PHE A CZ  1 
ATOM   2784  N N   . LEU A 1 357 ? 40.799  27.343  72.418  1.00 70.05  ? 432  LEU A N   1 
ATOM   2785  C CA  . LEU A 1 357 ? 39.685  27.914  73.167  1.00 78.33  ? 432  LEU A CA  1 
ATOM   2786  C C   . LEU A 1 357 ? 39.607  27.340  74.576  1.00 78.79  ? 432  LEU A C   1 
ATOM   2787  O O   . LEU A 1 357 ? 39.304  28.062  75.534  1.00 75.22  ? 432  LEU A O   1 
ATOM   2788  C CB  . LEU A 1 357 ? 38.385  27.664  72.404  1.00 69.49  ? 432  LEU A CB  1 
ATOM   2789  C CG  . LEU A 1 357 ? 37.048  27.955  73.079  1.00 61.29  ? 432  LEU A CG  1 
ATOM   2790  C CD1 . LEU A 1 357 ? 36.865  29.441  73.349  1.00 72.94  ? 432  LEU A CD1 1 
ATOM   2791  C CD2 . LEU A 1 357 ? 35.939  27.423  72.196  1.00 66.95  ? 432  LEU A CD2 1 
ATOM   2792  N N   . TYR A 1 358 ? 39.865  26.038  74.717  1.00 75.08  ? 433  TYR A N   1 
ATOM   2793  C CA  . TYR A 1 358 ? 39.896  25.408  76.032  1.00 76.40  ? 433  TYR A CA  1 
ATOM   2794  C C   . TYR A 1 358 ? 40.990  26.014  76.896  1.00 85.38  ? 433  TYR A C   1 
ATOM   2795  O O   . TYR A 1 358 ? 40.773  26.318  78.075  1.00 92.96  ? 433  TYR A O   1 
ATOM   2796  C CB  . TYR A 1 358 ? 40.108  23.901  75.873  1.00 78.32  ? 433  TYR A CB  1 
ATOM   2797  C CG  . TYR A 1 358 ? 40.306  23.156  77.173  1.00 79.92  ? 433  TYR A CG  1 
ATOM   2798  C CD1 . TYR A 1 358 ? 39.308  23.123  78.134  1.00 85.94  ? 433  TYR A CD1 1 
ATOM   2799  C CD2 . TYR A 1 358 ? 41.496  22.493  77.442  1.00 87.17  ? 433  TYR A CD2 1 
ATOM   2800  C CE1 . TYR A 1 358 ? 39.483  22.445  79.324  1.00 90.04  ? 433  TYR A CE1 1 
ATOM   2801  C CE2 . TYR A 1 358 ? 41.682  21.812  78.631  1.00 89.26  ? 433  TYR A CE2 1 
ATOM   2802  C CZ  . TYR A 1 358 ? 40.671  21.792  79.568  1.00 89.59  ? 433  TYR A CZ  1 
ATOM   2803  O OH  . TYR A 1 358 ? 40.847  21.117  80.754  1.00 96.12  ? 433  TYR A OH  1 
ATOM   2804  N N   . LYS A 1 359 ? 42.180  26.200  76.320  1.00 91.25  ? 434  LYS A N   1 
ATOM   2805  C CA  . LYS A 1 359 ? 43.269  26.794  77.086  1.00 91.34  ? 434  LYS A CA  1 
ATOM   2806  C C   . LYS A 1 359 ? 43.015  28.268  77.378  1.00 88.66  ? 434  LYS A C   1 
ATOM   2807  O O   . LYS A 1 359 ? 43.462  28.777  78.412  1.00 105.20 ? 434  LYS A O   1 
ATOM   2808  C CB  . LYS A 1 359 ? 44.597  26.612  76.353  1.00 72.26  ? 434  LYS A CB  1 
ATOM   2809  C CG  . LYS A 1 359 ? 45.075  25.175  76.328  1.00 74.38  ? 434  LYS A CG  1 
ATOM   2810  C CD  . LYS A 1 359 ? 45.937  24.898  75.117  1.00 94.68  ? 434  LYS A CD  1 
ATOM   2811  C CE  . LYS A 1 359 ? 46.730  23.622  75.314  1.00 94.46  ? 434  LYS A CE  1 
ATOM   2812  N NZ  . LYS A 1 359 ? 47.455  23.633  76.615  1.00 95.47  ? 434  LYS A NZ  1 
ATOM   2813  N N   . LYS A 1 360 ? 42.283  28.959  76.504  1.00 85.57  ? 435  LYS A N   1 
ATOM   2814  C CA  . LYS A 1 360 ? 42.072  30.391  76.690  1.00 76.69  ? 435  LYS A CA  1 
ATOM   2815  C C   . LYS A 1 360 ? 41.190  30.685  77.900  1.00 81.32  ? 435  LYS A C   1 
ATOM   2816  O O   . LYS A 1 360 ? 41.480  31.612  78.666  1.00 91.17  ? 435  LYS A O   1 
ATOM   2817  C CB  . LYS A 1 360 ? 41.477  31.001  75.422  1.00 86.24  ? 435  LYS A CB  1 
ATOM   2818  C CG  . LYS A 1 360 ? 41.305  32.508  75.481  1.00 92.72  ? 435  LYS A CG  1 
ATOM   2819  C CD  . LYS A 1 360 ? 42.484  33.228  76.111  1.00 90.91  ? 435  LYS A CD  1 
ATOM   2820  C CE  . LYS A 1 360 ? 42.470  34.698  75.731  1.00 78.53  ? 435  LYS A CE  1 
ATOM   2821  N NZ  . LYS A 1 360 ? 42.905  35.587  76.844  1.00 93.84  ? 435  LYS A NZ  1 
ATOM   2822  N N   . LEU A 1 361 ? 40.122  29.912  78.103  1.00 90.67  ? 436  LEU A N   1 
ATOM   2823  C CA  . LEU A 1 361 ? 39.175  30.262  79.157  1.00 112.25 ? 436  LEU A CA  1 
ATOM   2824  C C   . LEU A 1 361 ? 38.673  29.061  79.949  1.00 100.43 ? 436  LEU A C   1 
ATOM   2825  O O   . LEU A 1 361 ? 38.531  29.146  81.169  1.00 113.28 ? 436  LEU A O   1 
ATOM   2826  C CB  . LEU A 1 361 ? 37.997  31.046  78.563  1.00 88.04  ? 436  LEU A CB  1 
ATOM   2827  C CG  . LEU A 1 361 ? 37.098  30.400  77.509  1.00 83.32  ? 436  LEU A CG  1 
ATOM   2828  C CD1 . LEU A 1 361 ? 35.879  29.727  78.123  1.00 97.89  ? 436  LEU A CD1 1 
ATOM   2829  C CD2 . LEU A 1 361 ? 36.683  31.457  76.493  1.00 78.22  ? 436  LEU A CD2 1 
ATOM   2830  N N   . PHE A 1 362 ? 38.397  27.939  79.285  1.00 91.62  ? 437  PHE A N   1 
ATOM   2831  C CA  . PHE A 1 362 ? 37.921  26.761  80.006  1.00 88.90  ? 437  PHE A CA  1 
ATOM   2832  C C   . PHE A 1 362 ? 38.998  26.097  80.860  1.00 102.31 ? 437  PHE A C   1 
ATOM   2833  O O   . PHE A 1 362 ? 38.657  25.367  81.797  1.00 100.48 ? 437  PHE A O   1 
ATOM   2834  C CB  . PHE A 1 362 ? 37.334  25.747  79.028  1.00 74.11  ? 437  PHE A CB  1 
ATOM   2835  C CG  . PHE A 1 362 ? 36.172  26.262  78.239  1.00 82.07  ? 437  PHE A CG  1 
ATOM   2836  C CD1 . PHE A 1 362 ? 34.997  26.615  78.882  1.00 73.97  ? 437  PHE A CD1 1 
ATOM   2837  C CD2 . PHE A 1 362 ? 36.252  26.421  76.870  1.00 92.79  ? 437  PHE A CD2 1 
ATOM   2838  C CE1 . PHE A 1 362 ? 33.914  27.088  78.171  1.00 77.16  ? 437  PHE A CE1 1 
ATOM   2839  C CE2 . PHE A 1 362 ? 35.170  26.902  76.151  1.00 79.63  ? 437  PHE A CE2 1 
ATOM   2840  C CZ  . PHE A 1 362 ? 34.002  27.237  76.806  1.00 68.66  ? 437  PHE A CZ  1 
ATOM   2841  N N   . SER A 1 363 ? 40.281  26.312  80.558  1.00 116.44 ? 438  SER A N   1 
ATOM   2842  C CA  . SER A 1 363 ? 41.336  25.669  81.338  1.00 116.87 ? 438  SER A CA  1 
ATOM   2843  C C   . SER A 1 363 ? 41.369  26.221  82.756  1.00 126.97 ? 438  SER A C   1 
ATOM   2844  O O   . SER A 1 363 ? 41.340  25.466  83.736  1.00 121.96 ? 438  SER A O   1 
ATOM   2845  C CB  . SER A 1 363 ? 42.689  25.878  80.665  1.00 103.18 ? 438  SER A CB  1 
ATOM   2846  O OG  . SER A 1 363 ? 42.754  27.166  80.084  1.00 107.68 ? 438  SER A OG  1 
ATOM   2847  N N   . ARG A 1 364 ? 41.454  27.542  82.877  1.00 134.52 ? 439  ARG A N   1 
ATOM   2848  C CA  . ARG A 1 364 ? 41.365  28.197  84.172  1.00 146.70 ? 439  ARG A CA  1 
ATOM   2849  C C   . ARG A 1 364 ? 39.969  28.009  84.753  1.00 148.28 ? 439  ARG A C   1 
ATOM   2850  O O   . ARG A 1 364 ? 38.965  28.219  84.065  1.00 145.11 ? 439  ARG A O   1 
ATOM   2851  C CB  . ARG A 1 364 ? 41.705  29.680  84.020  1.00 161.24 ? 439  ARG A CB  1 
ATOM   2852  C CG  . ARG A 1 364 ? 40.872  30.383  82.960  1.00 183.54 ? 439  ARG A CG  1 
ATOM   2853  C CD  . ARG A 1 364 ? 40.870  31.890  83.118  1.00 205.88 ? 439  ARG A CD  1 
ATOM   2854  N NE  . ARG A 1 364 ? 39.610  32.457  82.653  1.00 241.44 ? 439  ARG A NE  1 
ATOM   2855  C CZ  . ARG A 1 364 ? 38.494  32.480  83.369  1.00 244.25 ? 439  ARG A CZ  1 
ATOM   2856  N NH1 . ARG A 1 364 ? 38.459  32.017  84.607  1.00 269.55 ? 439  ARG A NH1 1 
ATOM   2857  N NH2 . ARG A 1 364 ? 37.385  32.977  82.827  1.00 223.10 ? 439  ARG A NH2 1 
ATOM   2858  N N   . ARG A 1 365 ? 39.904  27.598  86.015  1.00 152.12 ? 440  ARG A N   1 
ATOM   2859  C CA  . ARG A 1 365 ? 38.614  27.289  86.619  1.00 145.64 ? 440  ARG A CA  1 
ATOM   2860  C C   . ARG A 1 365 ? 38.575  27.561  88.120  1.00 151.41 ? 440  ARG A C   1 
ATOM   2861  O O   . ARG A 1 365 ? 39.557  27.350  88.835  1.00 146.18 ? 440  ARG A O   1 
ATOM   2862  C CB  . ARG A 1 365 ? 38.245  25.831  86.331  1.00 134.85 ? 440  ARG A CB  1 
ATOM   2863  C CG  . ARG A 1 365 ? 38.640  24.835  87.409  1.00 129.19 ? 440  ARG A CG  1 
ATOM   2864  C CD  . ARG A 1 365 ? 37.862  23.539  87.270  1.00 112.05 ? 440  ARG A CD  1 
ATOM   2865  N NE  . ARG A 1 365 ? 38.525  22.452  87.978  1.00 130.71 ? 440  ARG A NE  1 
ATOM   2866  C CZ  . ARG A 1 365 ? 38.085  21.203  88.016  1.00 125.05 ? 440  ARG A CZ  1 
ATOM   2867  N NH1 . ARG A 1 365 ? 36.991  20.835  87.371  1.00 113.01 ? 440  ARG A NH1 1 
ATOM   2868  N NH2 . ARG A 1 365 ? 38.762  20.299  88.720  1.00 131.94 ? 440  ARG A NH2 1 
ATOM   2869  N N   . PRO A 1 381 ? 31.771  23.041  90.576  1.00 93.80  ? 456  PRO A N   1 
ATOM   2870  C CA  . PRO A 1 381 ? 33.107  23.404  90.093  1.00 106.56 ? 456  PRO A CA  1 
ATOM   2871  C C   . PRO A 1 381 ? 33.116  23.797  88.617  1.00 102.49 ? 456  PRO A C   1 
ATOM   2872  O O   . PRO A 1 381 ? 33.507  24.913  88.277  1.00 100.94 ? 456  PRO A O   1 
ATOM   2873  C CB  . PRO A 1 381 ? 33.923  22.125  90.323  1.00 82.04  ? 456  PRO A CB  1 
ATOM   2874  C CG  . PRO A 1 381 ? 32.912  21.028  90.387  1.00 87.65  ? 456  PRO A CG  1 
ATOM   2875  C CD  . PRO A 1 381 ? 31.711  21.644  91.036  1.00 78.36  ? 456  PRO A CD  1 
ATOM   2876  N N   . ASN A 1 382 ? 32.690  22.877  87.753  1.00 101.54 ? 457  ASN A N   1 
ATOM   2877  C CA  . ASN A 1 382 ? 32.599  23.140  86.324  1.00 98.54  ? 457  ASN A CA  1 
ATOM   2878  C C   . ASN A 1 382 ? 31.391  23.991  85.955  1.00 95.69  ? 457  ASN A C   1 
ATOM   2879  O O   . ASN A 1 382 ? 31.230  24.323  84.776  1.00 91.64  ? 457  ASN A O   1 
ATOM   2880  C CB  . ASN A 1 382 ? 32.543  21.817  85.550  1.00 90.33  ? 457  ASN A CB  1 
ATOM   2881  C CG  . ASN A 1 382 ? 33.892  21.129  85.464  1.00 92.63  ? 457  ASN A CG  1 
ATOM   2882  O OD1 . ASN A 1 382 ? 34.847  21.673  84.910  1.00 100.28 ? 457  ASN A OD1 1 
ATOM   2883  N ND2 . ASN A 1 382 ? 33.973  19.919  86.006  1.00 102.51 ? 457  ASN A ND2 1 
ATOM   2884  N N   . ALA A 1 383 ? 30.555  24.356  86.933  1.00 89.23  ? 458  ALA A N   1 
ATOM   2885  C CA  . ALA A 1 383 ? 29.302  25.044  86.635  1.00 87.17  ? 458  ALA A CA  1 
ATOM   2886  C C   . ALA A 1 383 ? 29.542  26.358  85.906  1.00 92.53  ? 458  ALA A C   1 
ATOM   2887  O O   . ALA A 1 383 ? 28.859  26.662  84.921  1.00 97.19  ? 458  ALA A O   1 
ATOM   2888  C CB  . ALA A 1 383 ? 28.515  25.283  87.923  1.00 90.51  ? 458  ALA A CB  1 
ATOM   2889  N N   . ASN A 1 384 ? 30.504  27.154  86.376  1.00 90.95  ? 459  ASN A N   1 
ATOM   2890  C CA  . ASN A 1 384 ? 30.810  28.398  85.680  1.00 93.25  ? 459  ASN A CA  1 
ATOM   2891  C C   . ASN A 1 384 ? 31.405  28.129  84.306  1.00 87.46  ? 459  ASN A C   1 
ATOM   2892  O O   . ASN A 1 384 ? 31.149  28.884  83.363  1.00 89.08  ? 459  ASN A O   1 
ATOM   2893  C CB  . ASN A 1 384 ? 31.752  29.257  86.521  1.00 100.22 ? 459  ASN A CB  1 
ATOM   2894  C CG  . ASN A 1 384 ? 31.048  30.442  87.149  1.00 104.62 ? 459  ASN A CG  1 
ATOM   2895  O OD1 . ASN A 1 384 ? 30.904  31.496  86.528  1.00 102.36 ? 459  ASN A OD1 1 
ATOM   2896  N ND2 . ASN A 1 384 ? 30.595  30.272  88.386  1.00 102.30 ? 459  ASN A ND2 1 
ATOM   2897  N N   . LEU A 1 385 ? 32.172  27.047  84.161  1.00 86.78  ? 460  LEU A N   1 
ATOM   2898  C CA  . LEU A 1 385 ? 32.673  26.680  82.841  1.00 93.86  ? 460  LEU A CA  1 
ATOM   2899  C C   . LEU A 1 385 ? 31.539  26.236  81.924  1.00 89.59  ? 460  LEU A C   1 
ATOM   2900  O O   . LEU A 1 385 ? 31.547  26.543  80.727  1.00 84.73  ? 460  LEU A O   1 
ATOM   2901  C CB  . LEU A 1 385 ? 33.729  25.582  82.962  1.00 86.55  ? 460  LEU A CB  1 
ATOM   2902  C CG  . LEU A 1 385 ? 34.946  25.874  83.838  1.00 89.17  ? 460  LEU A CG  1 
ATOM   2903  C CD1 . LEU A 1 385 ? 35.896  24.691  83.811  1.00 84.98  ? 460  LEU A CD1 1 
ATOM   2904  C CD2 . LEU A 1 385 ? 35.647  27.143  83.381  1.00 105.31 ? 460  LEU A CD2 1 
ATOM   2905  N N   . VAL A 1 386 ? 30.553  25.516  82.466  1.00 82.86  ? 461  VAL A N   1 
ATOM   2906  C CA  . VAL A 1 386 ? 29.403  25.109  81.661  1.00 78.04  ? 461  VAL A CA  1 
ATOM   2907  C C   . VAL A 1 386 ? 28.617  26.332  81.209  1.00 81.10  ? 461  VAL A C   1 
ATOM   2908  O O   . VAL A 1 386 ? 28.215  26.440  80.041  1.00 84.61  ? 461  VAL A O   1 
ATOM   2909  C CB  . VAL A 1 386 ? 28.520  24.127  82.454  1.00 68.79  ? 461  VAL A CB  1 
ATOM   2910  C CG1 . VAL A 1 386 ? 27.138  24.028  81.834  1.00 54.97  ? 461  VAL A CG1 1 
ATOM   2911  C CG2 . VAL A 1 386 ? 29.175  22.755  82.525  1.00 72.70  ? 461  VAL A CG2 1 
ATOM   2912  N N   . LYS A 1 387 ? 28.385  27.270  82.129  1.00 85.32  ? 462  LYS A N   1 
ATOM   2913  C CA  . LYS A 1 387 ? 27.707  28.510  81.776  1.00 87.76  ? 462  LYS A CA  1 
ATOM   2914  C C   . LYS A 1 387 ? 28.492  29.285  80.726  1.00 80.62  ? 462  LYS A C   1 
ATOM   2915  O O   . LYS A 1 387 ? 27.906  29.844  79.793  1.00 76.86  ? 462  LYS A O   1 
ATOM   2916  C CB  . LYS A 1 387 ? 27.490  29.354  83.034  1.00 92.20  ? 462  LYS A CB  1 
ATOM   2917  C CG  . LYS A 1 387 ? 26.536  28.717  84.034  1.00 82.12  ? 462  LYS A CG  1 
ATOM   2918  C CD  . LYS A 1 387 ? 26.844  29.148  85.459  1.00 101.95 ? 462  LYS A CD  1 
ATOM   2919  C CE  . LYS A 1 387 ? 25.888  30.225  85.945  1.00 110.68 ? 462  LYS A CE  1 
ATOM   2920  N NZ  . LYS A 1 387 ? 26.373  30.859  87.204  1.00 129.66 ? 462  LYS A NZ  1 
ATOM   2921  N N   . THR A 1 388 ? 29.823  29.310  80.848  1.00 72.85  ? 463  THR A N   1 
ATOM   2922  C CA  . THR A 1 388 ? 30.645  30.015  79.869  1.00 83.77  ? 463  THR A CA  1 
ATOM   2923  C C   . THR A 1 388 ? 30.567  29.346  78.503  1.00 83.22  ? 463  THR A C   1 
ATOM   2924  O O   . THR A 1 388 ? 30.570  30.023  77.471  1.00 80.44  ? 463  THR A O   1 
ATOM   2925  C CB  . THR A 1 388 ? 32.097  30.078  80.345  1.00 79.11  ? 463  THR A CB  1 
ATOM   2926  O OG1 . THR A 1 388 ? 32.139  30.540  81.701  1.00 92.26  ? 463  THR A OG1 1 
ATOM   2927  C CG2 . THR A 1 388 ? 32.888  31.039  79.477  1.00 73.76  ? 463  THR A CG2 1 
ATOM   2928  N N   . LEU A 1 389 ? 30.500  28.013  78.478  1.00 78.33  ? 464  LEU A N   1 
ATOM   2929  C CA  . LEU A 1 389 ? 30.341  27.301  77.213  1.00 67.60  ? 464  LEU A CA  1 
ATOM   2930  C C   . LEU A 1 389 ? 28.994  27.617  76.573  1.00 84.41  ? 464  LEU A C   1 
ATOM   2931  O O   . LEU A 1 389 ? 28.909  27.827  75.356  1.00 85.88  ? 464  LEU A O   1 
ATOM   2932  C CB  . LEU A 1 389 ? 30.492  25.796  77.438  1.00 45.38  ? 464  LEU A CB  1 
ATOM   2933  C CG  . LEU A 1 389 ? 30.445  24.901  76.199  1.00 60.60  ? 464  LEU A CG  1 
ATOM   2934  C CD1 . LEU A 1 389 ? 31.444  25.369  75.153  1.00 61.28  ? 464  LEU A CD1 1 
ATOM   2935  C CD2 . LEU A 1 389 ? 30.700  23.450  76.576  1.00 57.69  ? 464  LEU A CD2 1 
ATOM   2936  N N   . VAL A 1 390 ? 27.933  27.656  77.381  1.00 82.32  ? 465  VAL A N   1 
ATOM   2937  C CA  . VAL A 1 390 ? 26.617  28.028  76.867  1.00 63.10  ? 465  VAL A CA  1 
ATOM   2938  C C   . VAL A 1 390 ? 26.650  29.442  76.297  1.00 77.30  ? 465  VAL A C   1 
ATOM   2939  O O   . VAL A 1 390 ? 26.127  29.703  75.204  1.00 85.76  ? 465  VAL A O   1 
ATOM   2940  C CB  . VAL A 1 390 ? 25.553  27.886  77.971  1.00 63.19  ? 465  VAL A CB  1 
ATOM   2941  C CG1 . VAL A 1 390 ? 24.232  28.487  77.518  1.00 76.86  ? 465  VAL A CG1 1 
ATOM   2942  C CG2 . VAL A 1 390 ? 25.377  26.424  78.350  1.00 65.86  ? 465  VAL A CG2 1 
ATOM   2943  N N   . PHE A 1 391 ? 27.279  30.371  77.023  1.00 80.57  ? 466  PHE A N   1 
ATOM   2944  C CA  . PHE A 1 391 ? 27.339  31.758  76.570  1.00 89.98  ? 466  PHE A CA  1 
ATOM   2945  C C   . PHE A 1 391 ? 28.158  31.889  75.293  1.00 96.63  ? 466  PHE A C   1 
ATOM   2946  O O   . PHE A 1 391 ? 27.791  32.651  74.394  1.00 95.93  ? 466  PHE A O   1 
ATOM   2947  C CB  . PHE A 1 391 ? 27.919  32.658  77.665  1.00 85.78  ? 466  PHE A CB  1 
ATOM   2948  C CG  . PHE A 1 391 ? 27.201  32.563  78.985  1.00 91.91  ? 466  PHE A CG  1 
ATOM   2949  C CD1 . PHE A 1 391 ? 25.855  32.241  79.043  1.00 96.06  ? 466  PHE A CD1 1 
ATOM   2950  C CD2 . PHE A 1 391 ? 27.876  32.813  80.171  1.00 99.81  ? 466  PHE A CD2 1 
ATOM   2951  C CE1 . PHE A 1 391 ? 25.199  32.156  80.257  1.00 87.50  ? 466  PHE A CE1 1 
ATOM   2952  C CE2 . PHE A 1 391 ? 27.224  32.729  81.389  1.00 87.23  ? 466  PHE A CE2 1 
ATOM   2953  C CZ  . PHE A 1 391 ? 25.885  32.401  81.431  1.00 73.21  ? 466  PHE A CZ  1 
ATOM   2954  N N   . PHE A 1 392 ? 29.274  31.161  75.198  1.00 94.70  ? 467  PHE A N   1 
ATOM   2955  C CA  . PHE A 1 392 ? 30.077  31.183  73.981  1.00 100.23 ? 467  PHE A CA  1 
ATOM   2956  C C   . PHE A 1 392 ? 29.301  30.624  72.799  1.00 100.24 ? 467  PHE A C   1 
ATOM   2957  O O   . PHE A 1 392 ? 29.342  31.185  71.697  1.00 111.62 ? 467  PHE A O   1 
ATOM   2958  C CB  . PHE A 1 392 ? 31.366  30.389  74.186  1.00 80.84  ? 467  PHE A CB  1 
ATOM   2959  C CG  . PHE A 1 392 ? 32.130  30.148  72.919  1.00 83.63  ? 467  PHE A CG  1 
ATOM   2960  C CD1 . PHE A 1 392 ? 32.782  31.188  72.279  1.00 95.74  ? 467  PHE A CD1 1 
ATOM   2961  C CD2 . PHE A 1 392 ? 32.169  28.888  72.350  1.00 82.99  ? 467  PHE A CD2 1 
ATOM   2962  C CE1 . PHE A 1 392 ? 33.478  30.971  71.104  1.00 95.95  ? 467  PHE A CE1 1 
ATOM   2963  C CE2 . PHE A 1 392 ? 32.858  28.666  71.173  1.00 101.22 ? 467  PHE A CE2 1 
ATOM   2964  C CZ  . PHE A 1 392 ? 33.516  29.709  70.550  1.00 91.11  ? 467  PHE A CZ  1 
ATOM   2965  N N   . PHE A 1 393 ? 28.593  29.512  73.008  1.00 86.33  ? 468  PHE A N   1 
ATOM   2966  C CA  . PHE A 1 393 ? 27.816  28.913  71.929  1.00 87.69  ? 468  PHE A CA  1 
ATOM   2967  C C   . PHE A 1 393 ? 26.716  29.856  71.460  1.00 91.46  ? 468  PHE A C   1 
ATOM   2968  O O   . PHE A 1 393 ? 26.448  29.962  70.257  1.00 92.08  ? 468  PHE A O   1 
ATOM   2969  C CB  . PHE A 1 393 ? 27.236  27.575  72.392  1.00 75.99  ? 468  PHE A CB  1 
ATOM   2970  C CG  . PHE A 1 393 ? 26.201  27.004  71.467  1.00 74.52  ? 468  PHE A CG  1 
ATOM   2971  C CD1 . PHE A 1 393 ? 26.452  26.881  70.108  1.00 81.50  ? 468  PHE A CD1 1 
ATOM   2972  C CD2 . PHE A 1 393 ? 24.980  26.582  71.959  1.00 61.10  ? 468  PHE A CD2 1 
ATOM   2973  C CE1 . PHE A 1 393 ? 25.499  26.357  69.256  1.00 73.38  ? 468  PHE A CE1 1 
ATOM   2974  C CE2 . PHE A 1 393 ? 24.023  26.055  71.111  1.00 81.60  ? 468  PHE A CE2 1 
ATOM   2975  C CZ  . PHE A 1 393 ? 24.284  25.942  69.757  1.00 74.58  ? 468  PHE A CZ  1 
ATOM   2976  N N   . LEU A 1 394 ? 26.077  30.564  72.396  1.00 92.80  ? 469  LEU A N   1 
ATOM   2977  C CA  . LEU A 1 394 ? 25.039  31.515  72.011  1.00 95.75  ? 469  LEU A CA  1 
ATOM   2978  C C   . LEU A 1 394 ? 25.633  32.731  71.308  1.00 101.45 ? 469  LEU A C   1 
ATOM   2979  O O   . LEU A 1 394 ? 25.057  33.237  70.338  1.00 107.52 ? 469  LEU A O   1 
ATOM   2980  C CB  . LEU A 1 394 ? 24.234  31.941  73.239  1.00 92.52  ? 469  LEU A CB  1 
ATOM   2981  C CG  . LEU A 1 394 ? 23.163  30.963  73.727  1.00 76.36  ? 469  LEU A CG  1 
ATOM   2982  C CD1 . LEU A 1 394 ? 22.233  31.642  74.718  1.00 105.11 ? 469  LEU A CD1 1 
ATOM   2983  C CD2 . LEU A 1 394 ? 22.376  30.388  72.561  1.00 73.78  ? 469  LEU A CD2 1 
ATOM   2984  N N   . GLU A 1 395 ? 26.788  33.208  71.780  1.00 101.52 ? 470  GLU A N   1 
ATOM   2985  C CA  . GLU A 1 395 ? 27.406  34.399  71.205  1.00 108.34 ? 470  GLU A CA  1 
ATOM   2986  C C   . GLU A 1 395 ? 27.817  34.175  69.757  1.00 117.04 ? 470  GLU A C   1 
ATOM   2987  O O   . GLU A 1 395 ? 27.772  35.108  68.946  1.00 124.63 ? 470  GLU A O   1 
ATOM   2988  C CB  . GLU A 1 395 ? 28.623  34.814  72.036  1.00 132.79 ? 470  GLU A CB  1 
ATOM   2989  C CG  . GLU A 1 395 ? 28.314  35.732  73.212  1.00 140.20 ? 470  GLU A CG  1 
ATOM   2990  C CD  . GLU A 1 395 ? 29.038  35.320  74.484  1.00 154.83 ? 470  GLU A CD  1 
ATOM   2991  O OE1 . GLU A 1 395 ? 30.184  34.830  74.388  1.00 171.07 ? 470  GLU A OE1 1 
ATOM   2992  O OE2 . GLU A 1 395 ? 28.459  35.483  75.579  1.00 143.05 ? 470  GLU A OE2 1 
ATOM   2993  N N   . SER A 1 396 ? 28.228  32.957  69.415  1.00 123.94 ? 471  SER A N   1 
ATOM   2994  C CA  . SER A 1 396 ? 28.630  32.621  68.052  1.00 118.01 ? 471  SER A CA  1 
ATOM   2995  C C   . SER A 1 396 ? 27.383  32.221  67.277  1.00 111.31 ? 471  SER A C   1 
ATOM   2996  O O   . SER A 1 396 ? 26.863  31.114  67.441  1.00 108.65 ? 471  SER A O   1 
ATOM   2997  C CB  . SER A 1 396 ? 29.668  31.505  68.053  1.00 125.09 ? 471  SER A CB  1 
ATOM   2998  O OG  . SER A 1 396 ? 29.408  30.568  69.083  1.00 140.28 ? 471  SER A OG  1 
ATOM   2999  N N   . GLU A 1 397 ? 26.899  33.127  66.426  1.00 113.53 ? 472  GLU A N   1 
ATOM   3000  C CA  . GLU A 1 397 ? 25.729  32.859  65.599  1.00 123.54 ? 472  GLU A CA  1 
ATOM   3001  C C   . GLU A 1 397 ? 26.012  31.863  64.485  1.00 109.41 ? 472  GLU A C   1 
ATOM   3002  O O   . GLU A 1 397 ? 25.118  31.602  63.672  1.00 125.58 ? 472  GLU A O   1 
ATOM   3003  C CB  . GLU A 1 397 ? 25.206  34.162  64.988  1.00 132.18 ? 472  GLU A CB  1 
ATOM   3004  C CG  . GLU A 1 397 ? 24.299  34.976  65.897  1.00 138.44 ? 472  GLU A CG  1 
ATOM   3005  C CD  . GLU A 1 397 ? 25.058  35.656  67.022  1.00 168.50 ? 472  GLU A CD  1 
ATOM   3006  O OE1 . GLU A 1 397 ? 26.114  36.264  66.747  1.00 198.97 ? 472  GLU A OE1 1 
ATOM   3007  O OE2 . GLU A 1 397 ? 24.598  35.584  68.181  1.00 195.68 ? 472  GLU A OE2 1 
ATOM   3008  N N   . LEU A 1 398 ? 27.221  31.302  64.433  1.00 99.17  ? 473  LEU A N   1 
ATOM   3009  C CA  . LEU A 1 398 ? 27.620  30.484  63.293  1.00 96.84  ? 473  LEU A CA  1 
ATOM   3010  C C   . LEU A 1 398 ? 26.816  29.191  63.224  1.00 84.26  ? 473  LEU A C   1 
ATOM   3011  O O   . LEU A 1 398 ? 26.352  28.797  62.148  1.00 83.02  ? 473  LEU A O   1 
ATOM   3012  C CB  . LEU A 1 398 ? 29.118  30.188  63.370  1.00 96.20  ? 473  LEU A CB  1 
ATOM   3013  C CG  . LEU A 1 398 ? 30.034  31.396  63.159  1.00 91.44  ? 473  LEU A CG  1 
ATOM   3014  C CD1 . LEU A 1 398 ? 31.495  30.974  63.115  1.00 92.96  ? 473  LEU A CD1 1 
ATOM   3015  C CD2 . LEU A 1 398 ? 29.650  32.141  61.891  1.00 81.70  ? 473  LEU A CD2 1 
ATOM   3016  N N   . HIS A 1 399 ? 26.639  28.518  64.357  1.00 78.56  ? 474  HIS A N   1 
ATOM   3017  C CA  . HIS A 1 399 ? 25.975  27.226  64.394  1.00 77.21  ? 474  HIS A CA  1 
ATOM   3018  C C   . HIS A 1 399 ? 24.744  27.276  65.284  1.00 83.55  ? 474  HIS A C   1 
ATOM   3019  O O   . HIS A 1 399 ? 24.705  27.995  66.288  1.00 98.91  ? 474  HIS A O   1 
ATOM   3020  C CB  . HIS A 1 399 ? 26.924  26.139  64.890  1.00 69.71  ? 474  HIS A CB  1 
ATOM   3021  C CG  . HIS A 1 399 ? 27.755  25.534  63.807  1.00 65.38  ? 474  HIS A CG  1 
ATOM   3022  N ND1 . HIS A 1 399 ? 27.999  24.181  63.721  1.00 62.35  ? 474  HIS A ND1 1 
ATOM   3023  C CD2 . HIS A 1 399 ? 28.380  26.098  62.746  1.00 64.42  ? 474  HIS A CD2 1 
ATOM   3024  C CE1 . HIS A 1 399 ? 28.753  23.941  62.663  1.00 60.26  ? 474  HIS A CE1 1 
ATOM   3025  N NE2 . HIS A 1 399 ? 28.997  25.087  62.053  1.00 64.61  ? 474  HIS A NE2 1 
ATOM   3026  N N   . GLU A 1 400 ? 23.732  26.504  64.896  1.00 73.73  ? 475  GLU A N   1 
ATOM   3027  C CA  . GLU A 1 400 ? 22.521  26.359  65.686  1.00 69.32  ? 475  GLU A CA  1 
ATOM   3028  C C   . GLU A 1 400 ? 22.558  25.146  66.604  1.00 68.57  ? 475  GLU A C   1 
ATOM   3029  O O   . GLU A 1 400 ? 21.674  25.008  67.455  1.00 70.21  ? 475  GLU A O   1 
ATOM   3030  C CB  . GLU A 1 400 ? 21.298  26.272  64.766  1.00 78.40  ? 475  GLU A CB  1 
ATOM   3031  C CG  . GLU A 1 400 ? 21.118  27.478  63.855  1.00 89.63  ? 475  GLU A CG  1 
ATOM   3032  C CD  . GLU A 1 400 ? 19.756  27.508  63.183  1.00 89.15  ? 475  GLU A CD  1 
ATOM   3033  O OE1 . GLU A 1 400 ? 19.174  26.424  62.966  1.00 75.17  ? 475  GLU A OE1 1 
ATOM   3034  O OE2 . GLU A 1 400 ? 19.266  28.615  62.873  1.00 93.39  ? 475  GLU A OE2 1 
ATOM   3035  N N   . HIS A 1 401 ? 23.547  24.267  66.451  1.00 69.23  ? 476  HIS A N   1 
ATOM   3036  C CA  . HIS A 1 401 ? 23.732  23.130  67.340  1.00 75.55  ? 476  HIS A CA  1 
ATOM   3037  C C   . HIS A 1 401 ? 25.183  23.095  67.800  1.00 81.21  ? 476  HIS A C   1 
ATOM   3038  O O   . HIS A 1 401 ? 26.055  23.751  67.224  1.00 82.43  ? 476  HIS A O   1 
ATOM   3039  C CB  . HIS A 1 401 ? 23.352  21.805  66.662  1.00 62.29  ? 476  HIS A CB  1 
ATOM   3040  C CG  . HIS A 1 401 ? 24.031  21.580  65.346  1.00 58.25  ? 476  HIS A CG  1 
ATOM   3041  N ND1 . HIS A 1 401 ? 23.337  21.485  64.158  1.00 70.37  ? 476  HIS A ND1 1 
ATOM   3042  C CD2 . HIS A 1 401 ? 25.338  21.411  65.034  1.00 67.91  ? 476  HIS A CD2 1 
ATOM   3043  C CE1 . HIS A 1 401 ? 24.189  21.281  63.169  1.00 67.02  ? 476  HIS A CE1 1 
ATOM   3044  N NE2 . HIS A 1 401 ? 25.409  21.231  63.674  1.00 64.98  ? 476  HIS A NE2 1 
ATOM   3045  N N   . ALA A 1 402 ? 25.435  22.313  68.848  1.00 65.62  ? 477  ALA A N   1 
ATOM   3046  C CA  . ALA A 1 402 ? 26.747  22.246  69.476  1.00 71.79  ? 477  ALA A CA  1 
ATOM   3047  C C   . ALA A 1 402 ? 27.541  21.017  69.062  1.00 69.44  ? 477  ALA A C   1 
ATOM   3048  O O   . ALA A 1 402 ? 28.586  20.741  69.659  1.00 77.31  ? 477  ALA A O   1 
ATOM   3049  C CB  . ALA A 1 402 ? 26.602  22.278  70.997  1.00 84.25  ? 477  ALA A CB  1 
ATOM   3050  N N   . ALA A 1 403 ? 27.075  20.279  68.052  1.00 63.28  ? 478  ALA A N   1 
ATOM   3051  C CA  . ALA A 1 403 ? 27.720  19.022  67.685  1.00 69.04  ? 478  ALA A CA  1 
ATOM   3052  C C   . ALA A 1 403 ? 29.177  19.239  67.299  1.00 62.74  ? 478  ALA A C   1 
ATOM   3053  O O   . ALA A 1 403 ? 30.076  18.557  67.807  1.00 69.04  ? 478  ALA A O   1 
ATOM   3054  C CB  . ALA A 1 403 ? 26.954  18.359  66.541  1.00 77.50  ? 478  ALA A CB  1 
ATOM   3055  N N   . TYR A 1 404 ? 29.432  20.206  66.419  1.00 64.38  ? 479  TYR A N   1 
ATOM   3056  C CA  . TYR A 1 404 ? 30.787  20.427  65.932  1.00 66.82  ? 479  TYR A CA  1 
ATOM   3057  C C   . TYR A 1 404 ? 31.651  21.154  66.955  1.00 70.08  ? 479  TYR A C   1 
ATOM   3058  O O   . TYR A 1 404 ? 32.853  20.889  67.041  1.00 74.56  ? 479  TYR A O   1 
ATOM   3059  C CB  . TYR A 1 404 ? 30.721  21.191  64.611  1.00 57.78  ? 479  TYR A CB  1 
ATOM   3060  C CG  . TYR A 1 404 ? 30.058  20.380  63.520  1.00 62.38  ? 479  TYR A CG  1 
ATOM   3061  C CD1 . TYR A 1 404 ? 30.606  19.178  63.087  1.00 64.82  ? 479  TYR A CD1 1 
ATOM   3062  C CD2 . TYR A 1 404 ? 28.849  20.780  62.973  1.00 68.73  ? 479  TYR A CD2 1 
ATOM   3063  C CE1 . TYR A 1 404 ? 29.992  18.429  62.103  1.00 66.36  ? 479  TYR A CE1 1 
ATOM   3064  C CE2 . TYR A 1 404 ? 28.227  20.039  61.994  1.00 71.93  ? 479  TYR A CE2 1 
ATOM   3065  C CZ  . TYR A 1 404 ? 28.800  18.863  61.562  1.00 68.97  ? 479  TYR A CZ  1 
ATOM   3066  O OH  . TYR A 1 404 ? 28.171  18.126  60.584  1.00 70.47  ? 479  TYR A OH  1 
ATOM   3067  N N   . LEU A 1 405 ? 31.054  22.043  67.750  1.00 63.04  ? 480  LEU A N   1 
ATOM   3068  C CA  . LEU A 1 405 ? 31.758  22.632  68.885  1.00 54.10  ? 480  LEU A CA  1 
ATOM   3069  C C   . LEU A 1 405 ? 32.197  21.557  69.876  1.00 59.97  ? 480  LEU A C   1 
ATOM   3070  O O   . LEU A 1 405 ? 33.370  21.498  70.283  1.00 71.20  ? 480  LEU A O   1 
ATOM   3071  C CB  . LEU A 1 405 ? 30.843  23.653  69.562  1.00 42.79  ? 480  LEU A CB  1 
ATOM   3072  C CG  . LEU A 1 405 ? 31.266  24.382  70.832  1.00 59.66  ? 480  LEU A CG  1 
ATOM   3073  C CD1 . LEU A 1 405 ? 32.546  25.163  70.594  1.00 65.11  ? 480  LEU A CD1 1 
ATOM   3074  C CD2 . LEU A 1 405 ? 30.145  25.300  71.302  1.00 63.34  ? 480  LEU A CD2 1 
ATOM   3075  N N   . VAL A 1 406 ? 31.253  20.699  70.280  1.00 47.35  ? 481  VAL A N   1 
ATOM   3076  C CA  . VAL A 1 406 ? 31.563  19.605  71.197  1.00 51.20  ? 481  VAL A CA  1 
ATOM   3077  C C   . VAL A 1 406 ? 32.642  18.709  70.606  1.00 64.73  ? 481  VAL A C   1 
ATOM   3078  O O   . VAL A 1 406 ? 33.541  18.247  71.317  1.00 77.77  ? 481  VAL A O   1 
ATOM   3079  C CB  . VAL A 1 406 ? 30.287  18.810  71.533  1.00 43.07  ? 481  VAL A CB  1 
ATOM   3080  C CG1 . VAL A 1 406 ? 30.633  17.408  72.018  1.00 65.17  ? 481  VAL A CG1 1 
ATOM   3081  C CG2 . VAL A 1 406 ? 29.461  19.544  72.574  1.00 37.95  ? 481  VAL A CG2 1 
ATOM   3082  N N   . ASP A 1 407 ? 32.576  18.452  69.299  1.00 58.10  ? 482  ASP A N   1 
ATOM   3083  C CA  . ASP A 1 407 ? 33.611  17.647  68.660  1.00 53.74  ? 482  ASP A CA  1 
ATOM   3084  C C   . ASP A 1 407 ? 34.971  18.327  68.747  1.00 62.68  ? 482  ASP A C   1 
ATOM   3085  O O   . ASP A 1 407 ? 35.979  17.685  69.064  1.00 73.51  ? 482  ASP A O   1 
ATOM   3086  C CB  . ASP A 1 407 ? 33.242  17.373  67.205  1.00 59.73  ? 482  ASP A CB  1 
ATOM   3087  C CG  . ASP A 1 407 ? 34.263  16.506  66.508  1.00 64.92  ? 482  ASP A CG  1 
ATOM   3088  O OD1 . ASP A 1 407 ? 34.475  15.360  66.958  1.00 57.98  ? 482  ASP A OD1 1 
ATOM   3089  O OD2 . ASP A 1 407 ? 34.857  16.973  65.513  1.00 58.75  ? 482  ASP A OD2 1 
ATOM   3090  N N   . SER A 1 408 ? 35.017  19.632  68.463  1.00 57.43  ? 483  SER A N   1 
ATOM   3091  C CA  . SER A 1 408 ? 36.274  20.368  68.532  1.00 60.43  ? 483  SER A CA  1 
ATOM   3092  C C   . SER A 1 408 ? 36.901  20.264  69.913  1.00 69.02  ? 483  SER A C   1 
ATOM   3093  O O   . SER A 1 408 ? 38.123  20.118  70.040  1.00 70.23  ? 483  SER A O   1 
ATOM   3094  C CB  . SER A 1 408 ? 36.049  21.836  68.165  1.00 61.72  ? 483  SER A CB  1 
ATOM   3095  O OG  . SER A 1 408 ? 35.170  21.964  67.063  1.00 74.58  ? 483  SER A OG  1 
ATOM   3096  N N   . MET A 1 409 ? 36.086  20.336  70.963  1.00 69.80  ? 484  MET A N   1 
ATOM   3097  C CA  . MET A 1 409 ? 36.635  20.361  72.314  1.00 72.23  ? 484  MET A CA  1 
ATOM   3098  C C   . MET A 1 409 ? 36.510  19.036  73.060  1.00 76.92  ? 484  MET A C   1 
ATOM   3099  O O   . MET A 1 409 ? 36.748  19.000  74.273  1.00 82.19  ? 484  MET A O   1 
ATOM   3100  C CB  . MET A 1 409 ? 35.985  21.478  73.127  1.00 66.06  ? 484  MET A CB  1 
ATOM   3101  C CG  . MET A 1 409 ? 36.180  22.854  72.525  1.00 79.43  ? 484  MET A CG  1 
ATOM   3102  S SD  . MET A 1 409 ? 35.539  24.129  73.617  1.00 80.22  ? 484  MET A SD  1 
ATOM   3103  C CE  . MET A 1 409 ? 36.004  23.444  75.205  1.00 70.13  ? 484  MET A CE  1 
ATOM   3104  N N   . TRP A 1 410 ? 36.179  17.944  72.366  1.00 70.64  ? 485  TRP A N   1 
ATOM   3105  C CA  . TRP A 1 410 ? 35.912  16.690  73.064  1.00 84.16  ? 485  TRP A CA  1 
ATOM   3106  C C   . TRP A 1 410 ? 37.189  16.082  73.631  1.00 77.93  ? 485  TRP A C   1 
ATOM   3107  O O   . TRP A 1 410 ? 37.159  15.461  74.700  1.00 74.21  ? 485  TRP A O   1 
ATOM   3108  C CB  . TRP A 1 410 ? 35.221  15.703  72.120  1.00 84.64  ? 485  TRP A CB  1 
ATOM   3109  C CG  . TRP A 1 410 ? 34.678  14.466  72.793  1.00 90.88  ? 485  TRP A CG  1 
ATOM   3110  C CD1 . TRP A 1 410 ? 33.863  14.421  73.891  1.00 84.82  ? 485  TRP A CD1 1 
ATOM   3111  C CD2 . TRP A 1 410 ? 34.914  13.104  72.415  1.00 97.18  ? 485  TRP A CD2 1 
ATOM   3112  N NE1 . TRP A 1 410 ? 33.574  13.117  74.213  1.00 83.54  ? 485  TRP A NE1 1 
ATOM   3113  C CE2 . TRP A 1 410 ? 34.209  12.289  73.325  1.00 95.16  ? 485  TRP A CE2 1 
ATOM   3114  C CE3 . TRP A 1 410 ? 35.652  12.493  71.395  1.00 108.95 ? 485  TRP A CE3 1 
ATOM   3115  C CZ2 . TRP A 1 410 ? 34.220  10.896  73.246  1.00 104.24 ? 485  TRP A CZ2 1 
ATOM   3116  C CZ3 . TRP A 1 410 ? 35.661  11.108  71.318  1.00 121.96 ? 485  TRP A CZ3 1 
ATOM   3117  C CH2 . TRP A 1 410 ? 34.950  10.326  72.238  1.00 112.46 ? 485  TRP A CH2 1 
ATOM   3118  N N   . ASP A 1 411 ? 38.316  16.257  72.942  1.00 79.95  ? 486  ASP A N   1 
ATOM   3119  C CA  . ASP A 1 411 ? 39.571  15.678  73.407  1.00 74.64  ? 486  ASP A CA  1 
ATOM   3120  C C   . ASP A 1 411 ? 40.201  16.496  74.524  1.00 74.05  ? 486  ASP A C   1 
ATOM   3121  O O   . ASP A 1 411 ? 40.944  15.947  75.344  1.00 74.08  ? 486  ASP A O   1 
ATOM   3122  C CB  . ASP A 1 411 ? 40.546  15.547  72.239  1.00 66.08  ? 486  ASP A CB  1 
ATOM   3123  C CG  . ASP A 1 411 ? 39.901  14.932  71.020  1.00 95.97  ? 486  ASP A CG  1 
ATOM   3124  O OD1 . ASP A 1 411 ? 39.634  13.712  71.043  1.00 97.67  ? 486  ASP A OD1 1 
ATOM   3125  O OD2 . ASP A 1 411 ? 39.643  15.672  70.048  1.00 93.63  ? 486  ASP A OD2 1 
ATOM   3126  N N   . CYS A 1 412 ? 39.915  17.796  74.574  1.00 75.13  ? 487  CYS A N   1 
ATOM   3127  C CA  . CYS A 1 412 ? 40.498  18.691  75.568  1.00 48.75  ? 487  CYS A CA  1 
ATOM   3128  C C   . CYS A 1 412 ? 39.627  18.796  76.818  1.00 84.67  ? 487  CYS A C   1 
ATOM   3129  O O   . CYS A 1 412 ? 40.086  18.506  77.927  1.00 95.90  ? 487  CYS A O   1 
ATOM   3130  C CB  . CYS A 1 412 ? 40.718  20.077  74.955  1.00 50.23  ? 487  CYS A CB  1 
ATOM   3131  S SG  . CYS A 1 412 ? 41.269  20.063  73.232  1.00 88.19  ? 487  CYS A SG  1 
ATOM   3132  N N   . ALA A 1 413 ? 38.369  19.202  76.651  1.00 85.93  ? 488  ALA A N   1 
ATOM   3133  C CA  . ALA A 1 413 ? 37.451  19.439  77.765  1.00 76.48  ? 488  ALA A CA  1 
ATOM   3134  C C   . ALA A 1 413 ? 36.550  18.243  78.034  1.00 79.03  ? 488  ALA A C   1 
ATOM   3135  O O   . ALA A 1 413 ? 35.361  18.409  78.319  1.00 93.66  ? 488  ALA A O   1 
ATOM   3136  C CB  . ALA A 1 413 ? 36.613  20.685  77.501  1.00 90.93  ? 488  ALA A CB  1 
ATOM   3137  N N   . THR A 1 414 ? 37.094  17.026  77.976  1.00 67.43  ? 489  THR A N   1 
ATOM   3138  C CA  . THR A 1 414 ? 36.266  15.839  78.156  1.00 75.65  ? 489  THR A CA  1 
ATOM   3139  C C   . THR A 1 414 ? 35.667  15.776  79.560  1.00 83.65  ? 489  THR A C   1 
ATOM   3140  O O   . THR A 1 414 ? 34.509  15.376  79.726  1.00 89.07  ? 489  THR A O   1 
ATOM   3141  C CB  . THR A 1 414 ? 37.082  14.580  77.851  1.00 67.18  ? 489  THR A CB  1 
ATOM   3142  O OG1 . THR A 1 414 ? 36.255  13.420  78.008  1.00 86.01  ? 489  THR A OG1 1 
ATOM   3143  C CG2 . THR A 1 414 ? 38.298  14.483  78.767  1.00 82.05  ? 489  THR A CG2 1 
ATOM   3144  N N   . GLU A 1 415 ? 36.425  16.184  80.585  1.00 83.27  ? 490  GLU A N   1 
ATOM   3145  C CA  . GLU A 1 415 ? 35.892  16.148  81.946  1.00 79.91  ? 490  GLU A CA  1 
ATOM   3146  C C   . GLU A 1 415 ? 34.745  17.137  82.110  1.00 80.30  ? 490  GLU A C   1 
ATOM   3147  O O   . GLU A 1 415 ? 33.748  16.839  82.778  1.00 95.26  ? 490  GLU A O   1 
ATOM   3148  C CB  . GLU A 1 415 ? 37.002  16.430  82.970  1.00 97.49  ? 490  GLU A CB  1 
ATOM   3149  C CG  . GLU A 1 415 ? 37.481  17.898  83.161  1.00 106.27 ? 490  GLU A CG  1 
ATOM   3150  C CD  . GLU A 1 415 ? 37.860  18.661  81.886  1.00 116.00 ? 490  GLU A CD  1 
ATOM   3151  O OE1 . GLU A 1 415 ? 37.622  18.182  80.761  1.00 128.74 ? 490  GLU A OE1 1 
ATOM   3152  O OE2 . GLU A 1 415 ? 38.391  19.784  82.019  1.00 118.08 ? 490  GLU A OE2 1 
ATOM   3153  N N   . LEU A 1 416 ? 34.870  18.317  81.501  1.00 72.71  ? 491  LEU A N   1 
ATOM   3154  C CA  . LEU A 1 416 ? 33.804  19.309  81.558  1.00 82.55  ? 491  LEU A CA  1 
ATOM   3155  C C   . LEU A 1 416 ? 32.609  18.863  80.727  1.00 83.28  ? 491  LEU A C   1 
ATOM   3156  O O   . LEU A 1 416 ? 31.457  18.965  81.166  1.00 82.69  ? 491  LEU A O   1 
ATOM   3157  C CB  . LEU A 1 416 ? 34.336  20.656  81.070  1.00 74.45  ? 491  LEU A CB  1 
ATOM   3158  C CG  . LEU A 1 416 ? 33.337  21.710  80.591  1.00 65.14  ? 491  LEU A CG  1 
ATOM   3159  C CD1 . LEU A 1 416 ? 32.612  22.332  81.768  1.00 68.87  ? 491  LEU A CD1 1 
ATOM   3160  C CD2 . LEU A 1 416 ? 34.035  22.775  79.755  1.00 57.55  ? 491  LEU A CD2 1 
ATOM   3161  N N   . LEU A 1 417 ? 32.870  18.351  79.521  1.00 78.20  ? 492  LEU A N   1 
ATOM   3162  C CA  . LEU A 1 417 ? 31.790  17.928  78.638  1.00 69.05  ? 492  LEU A CA  1 
ATOM   3163  C C   . LEU A 1 417 ? 31.033  16.734  79.203  1.00 65.88  ? 492  LEU A C   1 
ATOM   3164  O O   . LEU A 1 417 ? 29.845  16.563  78.910  1.00 73.46  ? 492  LEU A O   1 
ATOM   3165  C CB  . LEU A 1 417 ? 32.351  17.599  77.254  1.00 67.10  ? 492  LEU A CB  1 
ATOM   3166  C CG  . LEU A 1 417 ? 32.878  18.775  76.428  1.00 56.95  ? 492  LEU A CG  1 
ATOM   3167  C CD1 . LEU A 1 417 ? 33.138  18.339  74.998  1.00 58.42  ? 492  LEU A CD1 1 
ATOM   3168  C CD2 . LEU A 1 417 ? 31.913  19.949  76.469  1.00 58.66  ? 492  LEU A CD2 1 
ATOM   3169  N N   . LYS A 1 418 ? 31.695  15.904  80.007  1.00 58.21  ? 493  LYS A N   1 
ATOM   3170  C CA  . LYS A 1 418 ? 31.075  14.725  80.595  1.00 70.50  ? 493  LYS A CA  1 
ATOM   3171  C C   . LYS A 1 418 ? 30.552  14.971  82.002  1.00 79.94  ? 493  LYS A C   1 
ATOM   3172  O O   . LYS A 1 418 ? 30.080  14.029  82.646  1.00 75.18  ? 493  LYS A O   1 
ATOM   3173  C CB  . LYS A 1 418 ? 32.066  13.557  80.615  1.00 76.66  ? 493  LYS A CB  1 
ATOM   3174  C CG  . LYS A 1 418 ? 32.449  13.044  79.239  1.00 57.76  ? 493  LYS A CG  1 
ATOM   3175  C CD  . LYS A 1 418 ? 32.728  11.554  79.260  1.00 55.42  ? 493  LYS A CD  1 
ATOM   3176  C CE  . LYS A 1 418 ? 32.978  11.032  77.860  1.00 63.22  ? 493  LYS A CE  1 
ATOM   3177  N NZ  . LYS A 1 418 ? 34.170  10.146  77.815  1.00 47.98  ? 493  LYS A NZ  1 
ATOM   3178  N N   . ASP A 1 419 ? 30.630  16.206  82.498  1.00 79.98  ? 494  ASP A N   1 
ATOM   3179  C CA  . ASP A 1 419 ? 30.025  16.567  83.778  1.00 83.85  ? 494  ASP A CA  1 
ATOM   3180  C C   . ASP A 1 419 ? 28.514  16.744  83.613  1.00 89.02  ? 494  ASP A C   1 
ATOM   3181  O O   . ASP A 1 419 ? 27.943  17.797  83.893  1.00 93.19  ? 494  ASP A O   1 
ATOM   3182  C CB  . ASP A 1 419 ? 30.672  17.829  84.337  1.00 84.51  ? 494  ASP A CB  1 
ATOM   3183  C CG  . ASP A 1 419 ? 30.439  17.993  85.827  1.00 98.66  ? 494  ASP A CG  1 
ATOM   3184  O OD1 . ASP A 1 419 ? 29.686  17.183  86.406  1.00 101.22 ? 494  ASP A OD1 1 
ATOM   3185  O OD2 . ASP A 1 419 ? 31.009  18.934  86.420  1.00 103.84 ? 494  ASP A OD2 1 
ATOM   3186  N N   . TRP A 1 420 ? 27.867  15.674  83.139  1.00 88.52  ? 495  TRP A N   1 
ATOM   3187  C CA  . TRP A 1 420 ? 26.429  15.725  82.906  1.00 85.32  ? 495  TRP A CA  1 
ATOM   3188  C C   . TRP A 1 420 ? 25.666  16.038  84.182  1.00 90.29  ? 495  TRP A C   1 
ATOM   3189  O O   . TRP A 1 420 ? 24.615  16.687  84.132  1.00 97.58  ? 495  TRP A O   1 
ATOM   3190  C CB  . TRP A 1 420 ? 25.944  14.403  82.312  1.00 82.70  ? 495  TRP A CB  1 
ATOM   3191  C CG  . TRP A 1 420 ? 26.609  14.044  81.022  1.00 74.65  ? 495  TRP A CG  1 
ATOM   3192  C CD1 . TRP A 1 420 ? 26.566  14.747  79.857  1.00 68.42  ? 495  TRP A CD1 1 
ATOM   3193  C CD2 . TRP A 1 420 ? 27.416  12.889  80.763  1.00 70.12  ? 495  TRP A CD2 1 
ATOM   3194  N NE1 . TRP A 1 420 ? 27.295  14.106  78.886  1.00 65.88  ? 495  TRP A NE1 1 
ATOM   3195  C CE2 . TRP A 1 420 ? 27.828  12.962  79.418  1.00 71.40  ? 495  TRP A CE2 1 
ATOM   3196  C CE3 . TRP A 1 420 ? 27.830  11.803  81.538  1.00 70.62  ? 495  TRP A CE3 1 
ATOM   3197  C CZ2 . TRP A 1 420 ? 28.632  11.990  78.832  1.00 68.05  ? 495  TRP A CZ2 1 
ATOM   3198  C CZ3 . TRP A 1 420 ? 28.627  10.840  80.956  1.00 89.41  ? 495  TRP A CZ3 1 
ATOM   3199  C CH2 . TRP A 1 420 ? 29.021  10.938  79.615  1.00 81.03  ? 495  TRP A CH2 1 
ATOM   3200  N N   . GLU A 1 421 ? 26.183  15.590  85.327  1.00 92.40  ? 496  GLU A N   1 
ATOM   3201  C CA  . GLU A 1 421 ? 25.522  15.832  86.604  1.00 99.05  ? 496  GLU A CA  1 
ATOM   3202  C C   . GLU A 1 421 ? 25.365  17.325  86.862  1.00 93.13  ? 496  GLU A C   1 
ATOM   3203  O O   . GLU A 1 421 ? 24.283  17.799  87.239  1.00 105.51 ? 496  GLU A O   1 
ATOM   3204  C CB  . GLU A 1 421 ? 26.332  15.177  87.728  1.00 95.65  ? 496  GLU A CB  1 
ATOM   3205  C CG  . GLU A 1 421 ? 25.515  14.650  88.887  1.00 93.34  ? 496  GLU A CG  1 
ATOM   3206  C CD  . GLU A 1 421 ? 24.587  15.690  89.472  1.00 133.61 ? 496  GLU A CD  1 
ATOM   3207  O OE1 . GLU A 1 421 ? 25.072  16.654  90.104  1.00 153.78 ? 496  GLU A OE1 1 
ATOM   3208  O OE2 . GLU A 1 421 ? 23.361  15.535  89.297  1.00 146.90 ? 496  GLU A OE2 1 
ATOM   3209  N N   . CYS A 1 422 ? 26.442  18.086  86.649  1.00 91.07  ? 497  CYS A N   1 
ATOM   3210  C CA  . CYS A 1 422 ? 26.380  19.523  86.874  1.00 91.93  ? 497  CYS A CA  1 
ATOM   3211  C C   . CYS A 1 422 ? 25.432  20.186  85.884  1.00 87.60  ? 497  CYS A C   1 
ATOM   3212  O O   . CYS A 1 422 ? 24.675  21.090  86.251  1.00 79.93  ? 497  CYS A O   1 
ATOM   3213  C CB  . CYS A 1 422 ? 27.779  20.134  86.780  1.00 90.74  ? 497  CYS A CB  1 
ATOM   3214  S SG  . CYS A 1 422 ? 27.768  21.899  86.394  1.00 99.62  ? 497  CYS A SG  1 
ATOM   3215  N N   . MET A 1 423 ? 25.421  19.715  84.635  1.00 89.01  ? 498  MET A N   1 
ATOM   3216  C CA  . MET A 1 423 ? 24.561  20.331  83.629  1.00 86.88  ? 498  MET A CA  1 
ATOM   3217  C C   . MET A 1 423 ? 23.084  20.100  83.939  1.00 88.60  ? 498  MET A C   1 
ATOM   3218  O O   . MET A 1 423 ? 22.288  21.049  83.968  1.00 97.28  ? 498  MET A O   1 
ATOM   3219  C CB  . MET A 1 423 ? 24.907  19.802  82.239  1.00 85.61  ? 498  MET A CB  1 
ATOM   3220  C CG  . MET A 1 423 ? 26.383  19.865  81.899  1.00 83.56  ? 498  MET A CG  1 
ATOM   3221  S SD  . MET A 1 423 ? 26.630  19.784  80.121  1.00 70.65  ? 498  MET A SD  1 
ATOM   3222  C CE  . MET A 1 423 ? 26.989  18.047  79.909  1.00 62.30  ? 498  MET A CE  1 
ATOM   3223  N N   . ASN A 1 424 ? 22.687  18.845  84.171  1.00 88.60  ? 499  ASN A N   1 
ATOM   3224  C CA  . ASN A 1 424 ? 21.275  18.608  84.464  1.00 91.53  ? 499  ASN A CA  1 
ATOM   3225  C C   . ASN A 1 424 ? 20.878  19.244  85.793  1.00 92.23  ? 499  ASN A C   1 
ATOM   3226  O O   . ASN A 1 424 ? 19.712  19.613  85.980  1.00 94.92  ? 499  ASN A O   1 
ATOM   3227  C CB  . ASN A 1 424 ? 20.920  17.113  84.471  1.00 90.07  ? 499  ASN A CB  1 
ATOM   3228  C CG  . ASN A 1 424 ? 21.430  16.383  85.710  1.00 107.67 ? 499  ASN A CG  1 
ATOM   3229  O OD1 . ASN A 1 424 ? 22.612  16.119  85.856  1.00 115.91 ? 499  ASN A OD1 1 
ATOM   3230  N ND2 . ASN A 1 424 ? 20.518  16.087  86.633  1.00 109.44 ? 499  ASN A ND2 1 
ATOM   3231  N N   . SER A 1 425 ? 21.829  19.404  86.723  1.00 102.53 ? 500  SER A N   1 
ATOM   3232  C CA  . SER A 1 425 ? 21.520  20.159  87.933  1.00 102.14 ? 500  SER A CA  1 
ATOM   3233  C C   . SER A 1 425 ? 21.259  21.625  87.616  1.00 94.42  ? 500  SER A C   1 
ATOM   3234  O O   . SER A 1 425 ? 20.362  22.238  88.203  1.00 115.55 ? 500  SER A O   1 
ATOM   3235  C CB  . SER A 1 425 ? 22.654  20.024  88.946  1.00 99.56  ? 500  SER A CB  1 
ATOM   3236  O OG  . SER A 1 425 ? 22.940  18.661  89.200  1.00 109.25 ? 500  SER A OG  1 
ATOM   3237  N N   . LEU A 1 426 ? 22.037  22.203  86.698  1.00 77.48  ? 501  LEU A N   1 
ATOM   3238  C CA  . LEU A 1 426 ? 21.782  23.575  86.269  1.00 84.37  ? 501  LEU A CA  1 
ATOM   3239  C C   . LEU A 1 426 ? 20.405  23.707  85.634  1.00 108.60 ? 501  LEU A C   1 
ATOM   3240  O O   . LEU A 1 426 ? 19.692  24.688  85.877  1.00 129.93 ? 501  LEU A O   1 
ATOM   3241  C CB  . LEU A 1 426 ? 22.861  24.032  85.289  1.00 88.19  ? 501  LEU A CB  1 
ATOM   3242  C CG  . LEU A 1 426 ? 24.163  24.559  85.887  1.00 89.97  ? 501  LEU A CG  1 
ATOM   3243  C CD1 . LEU A 1 426 ? 25.308  24.324  84.928  1.00 67.15  ? 501  LEU A CD1 1 
ATOM   3244  C CD2 . LEU A 1 426 ? 24.034  26.040  86.210  1.00 104.70 ? 501  LEU A CD2 1 
ATOM   3245  N N   . LEU A 1 427 ? 20.013  22.731  84.814  1.00 107.36 ? 502  LEU A N   1 
ATOM   3246  C CA  . LEU A 1 427 ? 18.704  22.805  84.171  1.00 92.22  ? 502  LEU A CA  1 
ATOM   3247  C C   . LEU A 1 427 ? 17.577  22.575  85.172  1.00 93.67  ? 502  LEU A C   1 
ATOM   3248  O O   . LEU A 1 427 ? 16.537  23.240  85.107  1.00 107.22 ? 502  LEU A O   1 
ATOM   3249  C CB  . LEU A 1 427 ? 18.629  21.801  83.026  1.00 82.18  ? 502  LEU A CB  1 
ATOM   3250  C CG  . LEU A 1 427 ? 19.554  22.132  81.857  1.00 85.22  ? 502  LEU A CG  1 
ATOM   3251  C CD1 . LEU A 1 427 ? 19.922  20.872  81.099  1.00 83.47  ? 502  LEU A CD1 1 
ATOM   3252  C CD2 . LEU A 1 427 ? 18.895  23.152  80.938  1.00 74.09  ? 502  LEU A CD2 1 
ATOM   3253  N N   . LEU A 1 428 ? 17.764  21.641  86.105  1.00 102.83 ? 503  LEU A N   1 
ATOM   3254  C CA  . LEU A 1 428 ? 16.754  21.356  87.117  1.00 98.86  ? 503  LEU A CA  1 
ATOM   3255  C C   . LEU A 1 428 ? 16.831  22.369  88.253  1.00 114.36 ? 503  LEU A C   1 
ATOM   3256  O O   . LEU A 1 428 ? 16.073  23.344  88.272  1.00 130.71 ? 503  LEU A O   1 
ATOM   3257  C CB  . LEU A 1 428 ? 16.920  19.931  87.651  1.00 86.45  ? 503  LEU A CB  1 
ATOM   3258  C CG  . LEU A 1 428 ? 16.483  18.815  86.697  1.00 82.99  ? 503  LEU A CG  1 
ATOM   3259  C CD1 . LEU A 1 428 ? 16.629  17.440  87.337  1.00 86.42  ? 503  LEU A CD1 1 
ATOM   3260  C CD2 . LEU A 1 428 ? 15.054  19.043  86.229  1.00 81.83  ? 503  LEU A CD2 1 
ATOM   3261  N N   . GLU A 1 429 ? 17.742  22.151  89.201  1.00 112.78 ? 504  GLU A N   1 
ATOM   3262  C CA  . GLU A 1 429 ? 17.899  23.086  90.308  1.00 119.74 ? 504  GLU A CA  1 
ATOM   3263  C C   . GLU A 1 429 ? 18.358  24.446  89.795  1.00 145.84 ? 504  GLU A C   1 
ATOM   3264  O O   . GLU A 1 429 ? 19.194  24.539  88.893  1.00 172.53 ? 504  GLU A O   1 
ATOM   3265  C CB  . GLU A 1 429 ? 18.906  22.545  91.325  1.00 115.83 ? 504  GLU A CB  1 
ATOM   3266  C CG  . GLU A 1 429 ? 18.756  21.068  91.647  1.00 120.27 ? 504  GLU A CG  1 
ATOM   3267  C CD  . GLU A 1 429 ? 20.097  20.378  91.806  1.00 111.38 ? 504  GLU A CD  1 
ATOM   3268  O OE1 . GLU A 1 429 ? 20.960  20.924  92.524  1.00 103.09 ? 504  GLU A OE1 1 
ATOM   3269  O OE2 . GLU A 1 429 ? 20.289  19.292  91.220  1.00 109.54 ? 504  GLU A OE2 1 
ATOM   3270  N N   . GLU A 1 430 ? 17.798  25.508  90.367  1.00 163.33 ? 505  GLU A N   1 
ATOM   3271  C CA  . GLU A 1 430 ? 18.193  26.853  89.961  1.00 172.93 ? 505  GLU A CA  1 
ATOM   3272  C C   . GLU A 1 430 ? 18.585  27.727  91.151  1.00 162.88 ? 505  GLU A C   1 
ATOM   3273  O O   . GLU A 1 430 ? 19.655  28.348  91.110  1.00 167.44 ? 505  GLU A O   1 
ATOM   3274  C CB  . GLU A 1 430 ? 17.082  27.537  89.155  1.00 185.89 ? 505  GLU A CB  1 
ATOM   3275  C CG  . GLU A 1 430 ? 16.465  26.686  88.062  1.00 186.07 ? 505  GLU A CG  1 
ATOM   3276  C CD  . GLU A 1 430 ? 14.958  26.815  88.018  1.00 201.06 ? 505  GLU A CD  1 
ATOM   3277  O OE1 . GLU A 1 430 ? 14.274  25.783  87.859  1.00 233.08 ? 505  GLU A OE1 1 
ATOM   3278  O OE2 . GLU A 1 430 ? 14.457  27.953  88.141  1.00 193.44 ? 505  GLU A OE2 1 
ATOM   3279  N N   . PRO A 1 431 ? 17.759  27.832  92.226  1.00 161.60 ? 506  PRO A N   1 
ATOM   3280  C CA  . PRO A 1 431 ? 18.123  28.742  93.324  1.00 174.73 ? 506  PRO A CA  1 
ATOM   3281  C C   . PRO A 1 431 ? 19.463  28.407  93.955  1.00 179.50 ? 506  PRO A C   1 
ATOM   3282  O O   . PRO A 1 431 ? 19.557  27.519  94.809  1.00 192.39 ? 506  PRO A O   1 
ATOM   3283  C CB  . PRO A 1 431 ? 16.980  28.566  94.332  1.00 178.16 ? 506  PRO A CB  1 
ATOM   3284  C CG  . PRO A 1 431 ? 15.845  28.055  93.542  1.00 166.48 ? 506  PRO A CG  1 
ATOM   3285  C CD  . PRO A 1 431 ? 16.443  27.208  92.464  1.00 165.37 ? 506  PRO A CD  1 
ATOM   3286  N N   . LEU A 1 432 ? 20.508  29.120  93.539  1.00 170.95 ? 507  LEU A N   1 
ATOM   3287  C CA  . LEU A 1 432 ? 21.845  28.958  94.102  1.00 165.20 ? 507  LEU A CA  1 
ATOM   3288  C C   . LEU A 1 432 ? 22.369  30.324  94.553  1.00 157.93 ? 507  LEU A C   1 
ATOM   3289  O O   . LEU A 1 432 ? 23.374  30.839  94.062  1.00 161.47 ? 507  LEU A O   1 
ATOM   3290  C CB  . LEU A 1 432 ? 22.766  28.262  93.101  1.00 177.28 ? 507  LEU A CB  1 
ATOM   3291  C CG  . LEU A 1 432 ? 22.329  26.819  92.823  1.00 202.47 ? 507  LEU A CG  1 
ATOM   3292  C CD1 . LEU A 1 432 ? 23.062  26.194  91.647  1.00 183.56 ? 507  LEU A CD1 1 
ATOM   3293  C CD2 . LEU A 1 432 ? 22.509  25.972  94.070  1.00 217.48 ? 507  LEU A CD2 1 
ATOM   3294  N N   . SER A 1 433 ? 21.649  30.906  95.517  1.00 148.36 ? 508  SER A N   1 
ATOM   3295  C CA  . SER A 1 433 ? 21.996  32.168  96.162  1.00 147.84 ? 508  SER A CA  1 
ATOM   3296  C C   . SER A 1 433 ? 22.112  33.305  95.156  1.00 146.76 ? 508  SER A C   1 
ATOM   3297  O O   . SER A 1 433 ? 21.122  33.695  94.529  1.00 143.82 ? 508  SER A O   1 
ATOM   3298  C CB  . SER A 1 433 ? 23.299  32.026  96.957  1.00 137.95 ? 508  SER A CB  1 
ATOM   3299  O OG  . SER A 1 433 ? 23.597  33.214  97.669  1.00 135.51 ? 508  SER A OG  1 
ATOM   3300  N N   . GLY A 1 434 ? 23.320  33.846  95.005  1.00 132.18 ? 509  GLY A N   1 
ATOM   3301  C CA  . GLY A 1 434 ? 23.569  34.934  94.083  1.00 114.72 ? 509  GLY A CA  1 
ATOM   3302  C C   . GLY A 1 434 ? 23.538  34.570  92.616  1.00 125.57 ? 509  GLY A C   1 
ATOM   3303  O O   . GLY A 1 434 ? 23.492  35.476  91.778  1.00 127.38 ? 509  GLY A O   1 
ATOM   3304  N N   . GLU A 1 435 ? 23.548  33.281  92.279  1.00 138.47 ? 510  GLU A N   1 
ATOM   3305  C CA  . GLU A 1 435 ? 23.568  32.885  90.878  1.00 142.43 ? 510  GLU A CA  1 
ATOM   3306  C C   . GLU A 1 435 ? 22.272  33.282  90.178  1.00 137.15 ? 510  GLU A C   1 
ATOM   3307  O O   . GLU A 1 435 ? 21.172  33.011  90.671  1.00 136.82 ? 510  GLU A O   1 
ATOM   3308  C CB  . GLU A 1 435 ? 23.803  31.380  90.756  1.00 148.24 ? 510  GLU A CB  1 
ATOM   3309  C CG  . GLU A 1 435 ? 23.378  30.812  89.407  1.00 142.82 ? 510  GLU A CG  1 
ATOM   3310  C CD  . GLU A 1 435 ? 23.280  29.307  89.423  1.00 152.55 ? 510  GLU A CD  1 
ATOM   3311  O OE1 . GLU A 1 435 ? 24.057  28.678  90.166  1.00 192.90 ? 510  GLU A OE1 1 
ATOM   3312  O OE2 . GLU A 1 435 ? 22.403  28.755  88.722  1.00 146.55 ? 510  GLU A OE2 1 
ATOM   3313  N N   . GLU A 1 436 ? 22.414  33.932  89.025  1.00 129.93 ? 511  GLU A N   1 
ATOM   3314  C CA  . GLU A 1 436 ? 21.269  34.346  88.229  1.00 131.19 ? 511  GLU A CA  1 
ATOM   3315  C C   . GLU A 1 436 ? 20.724  33.155  87.451  1.00 133.29 ? 511  GLU A C   1 
ATOM   3316  O O   . GLU A 1 436 ? 21.489  32.390  86.855  1.00 135.08 ? 511  GLU A O   1 
ATOM   3317  C CB  . GLU A 1 436 ? 21.673  35.470  87.274  1.00 124.05 ? 511  GLU A CB  1 
ATOM   3318  C CG  . GLU A 1 436 ? 20.595  35.898  86.306  1.00 143.22 ? 511  GLU A CG  1 
ATOM   3319  C CD  . GLU A 1 436 ? 19.313  36.293  87.011  1.00 158.43 ? 511  GLU A CD  1 
ATOM   3320  O OE1 . GLU A 1 436 ? 19.340  37.272  87.785  1.00 163.33 ? 511  GLU A OE1 1 
ATOM   3321  O OE2 . GLU A 1 436 ? 18.275  35.638  86.779  1.00 155.46 ? 511  GLU A OE2 1 
ATOM   3322  N N   . ALA A 1 437 ? 19.402  32.991  87.474  1.00 133.59 ? 512  ALA A N   1 
ATOM   3323  C CA  . ALA A 1 437 ? 18.765  31.914  86.730  1.00 110.46 ? 512  ALA A CA  1 
ATOM   3324  C C   . ALA A 1 437 ? 18.996  32.092  85.235  1.00 102.37 ? 512  ALA A C   1 
ATOM   3325  O O   . ALA A 1 437 ? 18.890  33.199  84.698  1.00 109.74 ? 512  ALA A O   1 
ATOM   3326  C CB  . ALA A 1 437 ? 17.267  31.874  87.033  1.00 107.80 ? 512  ALA A CB  1 
ATOM   3327  N N   . LEU A 1 438 ? 19.314  30.988  84.566  1.00 83.01  ? 513  LEU A N   1 
ATOM   3328  C CA  . LEU A 1 438 ? 19.624  31.031  83.145  1.00 96.90  ? 513  LEU A CA  1 
ATOM   3329  C C   . LEU A 1 438 ? 18.405  31.467  82.343  1.00 94.31  ? 513  LEU A C   1 
ATOM   3330  O O   . LEU A 1 438 ? 17.273  31.068  82.633  1.00 98.36  ? 513  LEU A O   1 
ATOM   3331  C CB  . LEU A 1 438 ? 20.098  29.655  82.675  1.00 98.68  ? 513  LEU A CB  1 
ATOM   3332  C CG  . LEU A 1 438 ? 21.603  29.411  82.552  1.00 77.89  ? 513  LEU A CG  1 
ATOM   3333  C CD1 . LEU A 1 438 ? 22.324  29.764  83.844  1.00 114.30 ? 513  LEU A CD1 1 
ATOM   3334  C CD2 . LEU A 1 438 ? 21.870  27.968  82.162  1.00 71.80  ? 513  LEU A CD2 1 
ATOM   3335  N N   . THR A 1 439 ? 18.641  32.300  81.332  1.00 78.72  ? 514  THR A N   1 
ATOM   3336  C CA  . THR A 1 439 ? 17.576  32.651  80.408  1.00 80.50  ? 514  THR A CA  1 
ATOM   3337  C C   . THR A 1 439 ? 17.087  31.402  79.685  1.00 98.05  ? 514  THR A C   1 
ATOM   3338  O O   . THR A 1 439 ? 17.814  30.414  79.542  1.00 106.63 ? 514  THR A O   1 
ATOM   3339  C CB  . THR A 1 439 ? 18.057  33.694  79.399  1.00 90.14  ? 514  THR A CB  1 
ATOM   3340  O OG1 . THR A 1 439 ? 18.776  33.046  78.343  1.00 113.86 ? 514  THR A OG1 1 
ATOM   3341  C CG2 . THR A 1 439 ? 18.968  34.706  80.076  1.00 91.01  ? 514  THR A CG2 1 
ATOM   3342  N N   . ASP A 1 440 ? 15.827  31.446  79.245  1.00 108.07 ? 515  ASP A N   1 
ATOM   3343  C CA  . ASP A 1 440 ? 15.243  30.294  78.568  1.00 114.53 ? 515  ASP A CA  1 
ATOM   3344  C C   . ASP A 1 440 ? 16.073  29.900  77.352  1.00 103.95 ? 515  ASP A C   1 
ATOM   3345  O O   . ASP A 1 440 ? 16.243  28.709  77.060  1.00 105.21 ? 515  ASP A O   1 
ATOM   3346  C CB  . ASP A 1 440 ? 13.801  30.602  78.166  1.00 113.81 ? 515  ASP A CB  1 
ATOM   3347  C CG  . ASP A 1 440 ? 12.920  29.376  78.197  1.00 115.91 ? 515  ASP A CG  1 
ATOM   3348  O OD1 . ASP A 1 440 ? 13.084  28.551  79.119  1.00 106.08 ? 515  ASP A OD1 1 
ATOM   3349  O OD2 . ASP A 1 440 ? 12.064  29.240  77.299  1.00 127.16 ? 515  ASP A OD2 1 
ATOM   3350  N N   . ARG A 1 441 ? 16.609  30.894  76.638  1.00 87.01  ? 516  ARG A N   1 
ATOM   3351  C CA  . ARG A 1 441 ? 17.483  30.607  75.508  1.00 98.17  ? 516  ARG A CA  1 
ATOM   3352  C C   . ARG A 1 441 ? 18.737  29.876  75.965  1.00 90.62  ? 516  ARG A C   1 
ATOM   3353  O O   . ARG A 1 441 ? 19.200  28.939  75.302  1.00 93.98  ? 516  ARG A O   1 
ATOM   3354  C CB  . ARG A 1 441 ? 17.854  31.905  74.793  1.00 103.11 ? 516  ARG A CB  1 
ATOM   3355  C CG  . ARG A 1 441 ? 17.762  31.832  73.281  1.00 102.49 ? 516  ARG A CG  1 
ATOM   3356  C CD  . ARG A 1 441 ? 17.946  33.208  72.662  1.00 104.80 ? 516  ARG A CD  1 
ATOM   3357  N NE  . ARG A 1 441 ? 16.741  34.023  72.763  1.00 113.28 ? 516  ARG A NE  1 
ATOM   3358  C CZ  . ARG A 1 441 ? 15.857  34.190  71.788  1.00 132.57 ? 516  ARG A CZ  1 
ATOM   3359  N NH1 . ARG A 1 441 ? 15.999  33.592  70.617  1.00 127.22 ? 516  ARG A NH1 1 
ATOM   3360  N NH2 . ARG A 1 441 ? 14.805  34.978  71.993  1.00 133.25 ? 516  ARG A NH2 1 
ATOM   3361  N N   . GLN A 1 442 ? 19.300  30.293  77.102  1.00 89.45  ? 517  GLN A N   1 
ATOM   3362  C CA  . GLN A 1 442 ? 20.463  29.607  77.648  1.00 88.72  ? 517  GLN A CA  1 
ATOM   3363  C C   . GLN A 1 442 ? 20.114  28.193  78.094  1.00 88.28  ? 517  GLN A C   1 
ATOM   3364  O O   . GLN A 1 442 ? 20.943  27.286  77.971  1.00 91.58  ? 517  GLN A O   1 
ATOM   3365  C CB  . GLN A 1 442 ? 21.050  30.410  78.809  1.00 84.05  ? 517  GLN A CB  1 
ATOM   3366  C CG  . GLN A 1 442 ? 21.992  31.525  78.377  1.00 92.18  ? 517  GLN A CG  1 
ATOM   3367  C CD  . GLN A 1 442 ? 21.917  32.738  79.284  1.00 96.23  ? 517  GLN A CD  1 
ATOM   3368  O OE1 . GLN A 1 442 ? 21.543  32.630  80.452  1.00 95.93  ? 517  GLN A OE1 1 
ATOM   3369  N NE2 . GLN A 1 442 ? 22.281  33.900  78.752  1.00 75.55  ? 517  GLN A NE2 1 
ATOM   3370  N N   . GLU A 1 443 ? 18.892  27.980  78.588  1.00 78.97  ? 518  GLU A N   1 
ATOM   3371  C CA  . GLU A 1 443 ? 18.473  26.634  78.966  1.00 80.90  ? 518  GLU A CA  1 
ATOM   3372  C C   . GLU A 1 443 ? 18.356  25.732  77.744  1.00 81.21  ? 518  GLU A C   1 
ATOM   3373  O O   . GLU A 1 443 ? 18.736  24.554  77.791  1.00 82.02  ? 518  GLU A O   1 
ATOM   3374  C CB  . GLU A 1 443 ? 17.146  26.696  79.721  1.00 98.70  ? 518  GLU A CB  1 
ATOM   3375  C CG  . GLU A 1 443 ? 17.217  27.474  81.024  1.00 83.32  ? 518  GLU A CG  1 
ATOM   3376  C CD  . GLU A 1 443 ? 15.856  27.680  81.656  1.00 100.70 ? 518  GLU A CD  1 
ATOM   3377  O OE1 . GLU A 1 443 ? 15.288  26.697  82.175  1.00 96.80  ? 518  GLU A OE1 1 
ATOM   3378  O OE2 . GLU A 1 443 ? 15.355  28.825  81.634  1.00 126.36 ? 518  GLU A OE2 1 
ATOM   3379  N N   . SER A 1 444 ? 17.833  26.269  76.639  1.00 86.45  ? 519  SER A N   1 
ATOM   3380  C CA  . SER A 1 444 ? 17.791  25.504  75.396  1.00 89.16  ? 519  SER A CA  1 
ATOM   3381  C C   . SER A 1 444 ? 19.197  25.188  74.892  1.00 85.80  ? 519  SER A C   1 
ATOM   3382  O O   . SER A 1 444 ? 19.478  24.055  74.479  1.00 87.23  ? 519  SER A O   1 
ATOM   3383  C CB  . SER A 1 444 ? 16.998  26.273  74.341  1.00 109.56 ? 519  SER A CB  1 
ATOM   3384  O OG  . SER A 1 444 ? 15.760  26.720  74.863  1.00 113.67 ? 519  SER A OG  1 
ATOM   3385  N N   . ALA A 1 445 ? 20.095  26.175  74.919  1.00 82.72  ? 520  ALA A N   1 
ATOM   3386  C CA  . ALA A 1 445 ? 21.477  25.917  74.525  1.00 69.91  ? 520  ALA A CA  1 
ATOM   3387  C C   . ALA A 1 445 ? 22.107  24.842  75.403  1.00 68.62  ? 520  ALA A C   1 
ATOM   3388  O O   . ALA A 1 445 ? 22.865  23.992  74.917  1.00 80.02  ? 520  ALA A O   1 
ATOM   3389  C CB  . ALA A 1 445 ? 22.291  27.208  74.587  1.00 64.64  ? 520  ALA A CB  1 
ATOM   3390  N N   . LEU A 1 446 ? 21.787  24.854  76.699  1.00 62.26  ? 521  LEU A N   1 
ATOM   3391  C CA  . LEU A 1 446 ? 22.359  23.874  77.614  1.00 69.84  ? 521  LEU A CA  1 
ATOM   3392  C C   . LEU A 1 446 ? 21.825  22.473  77.340  1.00 78.57  ? 521  LEU A C   1 
ATOM   3393  O O   . LEU A 1 446 ? 22.588  21.501  77.382  1.00 74.71  ? 521  LEU A O   1 
ATOM   3394  C CB  . LEU A 1 446 ? 22.081  24.279  79.061  1.00 63.59  ? 521  LEU A CB  1 
ATOM   3395  C CG  . LEU A 1 446 ? 22.739  23.412  80.139  1.00 62.78  ? 521  LEU A CG  1 
ATOM   3396  C CD1 . LEU A 1 446 ? 24.182  23.089  79.772  1.00 68.69  ? 521  LEU A CD1 1 
ATOM   3397  C CD2 . LEU A 1 446 ? 22.664  24.084  81.497  1.00 62.59  ? 521  LEU A CD2 1 
ATOM   3398  N N   . ILE A 1 447 ? 20.522  22.337  77.073  1.00 79.35  ? 522  ILE A N   1 
ATOM   3399  C CA  . ILE A 1 447 ? 20.030  20.991  76.781  1.00 80.27  ? 522  ILE A CA  1 
ATOM   3400  C C   . ILE A 1 447 ? 20.614  20.509  75.460  1.00 80.90  ? 522  ILE A C   1 
ATOM   3401  O O   . ILE A 1 447 ? 20.937  19.324  75.315  1.00 82.26  ? 522  ILE A O   1 
ATOM   3402  C CB  . ILE A 1 447 ? 18.484  20.898  76.806  1.00 79.14  ? 522  ILE A CB  1 
ATOM   3403  C CG1 . ILE A 1 447 ? 17.787  21.986  75.989  1.00 86.27  ? 522  ILE A CG1 1 
ATOM   3404  C CG2 . ILE A 1 447 ? 17.962  20.923  78.227  1.00 73.05  ? 522  ILE A CG2 1 
ATOM   3405  C CD1 . ILE A 1 447 ? 17.609  21.642  74.523  1.00 88.67  ? 522  ILE A CD1 1 
ATOM   3406  N N   . GLU A 1 448 ? 20.827  21.421  74.506  1.00 76.41  ? 523  GLU A N   1 
ATOM   3407  C CA  . GLU A 1 448 ? 21.472  21.042  73.252  1.00 78.22  ? 523  GLU A CA  1 
ATOM   3408  C C   . GLU A 1 448 ? 22.883  20.515  73.493  1.00 79.28  ? 523  GLU A C   1 
ATOM   3409  O O   . GLU A 1 448 ? 23.260  19.449  72.986  1.00 82.80  ? 523  GLU A O   1 
ATOM   3410  C CB  . GLU A 1 448 ? 21.501  22.241  72.301  1.00 72.72  ? 523  GLU A CB  1 
ATOM   3411  C CG  . GLU A 1 448 ? 22.354  22.044  71.058  1.00 74.69  ? 523  GLU A CG  1 
ATOM   3412  C CD  . GLU A 1 448 ? 21.714  21.088  70.075  1.00 84.34  ? 523  GLU A CD  1 
ATOM   3413  O OE1 . GLU A 1 448 ? 20.540  21.310  69.717  1.00 93.81  ? 523  GLU A OE1 1 
ATOM   3414  O OE2 . GLU A 1 448 ? 22.385  20.125  69.649  1.00 83.25  ? 523  GLU A OE2 1 
ATOM   3415  N N   . ILE A 1 449 ? 23.678  21.253  74.272  1.00 71.88  ? 524  ILE A N   1 
ATOM   3416  C CA  . ILE A 1 449 ? 25.064  20.859  74.520  1.00 70.01  ? 524  ILE A CA  1 
ATOM   3417  C C   . ILE A 1 449 ? 25.116  19.547  75.293  1.00 69.30  ? 524  ILE A C   1 
ATOM   3418  O O   . ILE A 1 449 ? 25.945  18.669  75.010  1.00 69.16  ? 524  ILE A O   1 
ATOM   3419  C CB  . ILE A 1 449 ? 25.812  21.984  75.260  1.00 69.97  ? 524  ILE A CB  1 
ATOM   3420  C CG1 . ILE A 1 449 ? 25.898  23.233  74.383  1.00 69.05  ? 524  ILE A CG1 1 
ATOM   3421  C CG2 . ILE A 1 449 ? 27.203  21.524  75.669  1.00 48.15  ? 524  ILE A CG2 1 
ATOM   3422  C CD1 . ILE A 1 449 ? 26.453  24.446  75.094  1.00 63.68  ? 524  ILE A CD1 1 
ATOM   3423  N N   . MET A 1 450 ? 24.235  19.396  76.285  1.00 61.79  ? 525  MET A N   1 
ATOM   3424  C CA  . MET A 1 450 ? 24.175  18.162  77.058  1.00 69.58  ? 525  MET A CA  1 
ATOM   3425  C C   . MET A 1 450 ? 23.850  16.975  76.162  1.00 73.59  ? 525  MET A C   1 
ATOM   3426  O O   . MET A 1 450 ? 24.484  15.917  76.257  1.00 73.86  ? 525  MET A O   1 
ATOM   3427  C CB  . MET A 1 450 ? 23.140  18.303  78.173  1.00 62.05  ? 525  MET A CB  1 
ATOM   3428  C CG  . MET A 1 450 ? 23.152  17.176  79.188  1.00 67.68  ? 525  MET A CG  1 
ATOM   3429  S SD  . MET A 1 450 ? 21.837  17.331  80.414  1.00 77.15  ? 525  MET A SD  1 
ATOM   3430  C CE  . MET A 1 450 ? 20.380  17.323  79.372  1.00 67.06  ? 525  MET A CE  1 
ATOM   3431  N N   . LEU A 1 451 ? 22.863  17.139  75.277  1.00 69.24  ? 526  LEU A N   1 
ATOM   3432  C CA  . LEU A 1 451 ? 22.511  16.072  74.347  1.00 71.44  ? 526  LEU A CA  1 
ATOM   3433  C C   . LEU A 1 451 ? 23.677  15.722  73.430  1.00 73.81  ? 526  LEU A C   1 
ATOM   3434  O O   . LEU A 1 451 ? 23.935  14.541  73.168  1.00 80.80  ? 526  LEU A O   1 
ATOM   3435  C CB  . LEU A 1 451 ? 21.290  16.484  73.525  1.00 70.09  ? 526  LEU A CB  1 
ATOM   3436  C CG  . LEU A 1 451 ? 21.055  15.715  72.226  1.00 65.39  ? 526  LEU A CG  1 
ATOM   3437  C CD1 . LEU A 1 451 ? 20.296  14.422  72.481  1.00 69.18  ? 526  LEU A CD1 1 
ATOM   3438  C CD2 . LEU A 1 451 ? 20.326  16.594  71.227  1.00 72.32  ? 526  LEU A CD2 1 
ATOM   3439  N N   . CYS A 1 452 ? 24.390  16.733  72.925  1.00 65.20  ? 527  CYS A N   1 
ATOM   3440  C CA  . CYS A 1 452 ? 25.515  16.453  72.034  1.00 64.97  ? 527  CYS A CA  1 
ATOM   3441  C C   . CYS A 1 452 ? 26.618  15.688  72.754  1.00 66.45  ? 527  CYS A C   1 
ATOM   3442  O O   . CYS A 1 452 ? 27.185  14.737  72.202  1.00 67.51  ? 527  CYS A O   1 
ATOM   3443  C CB  . CYS A 1 452 ? 26.066  17.746  71.436  1.00 59.49  ? 527  CYS A CB  1 
ATOM   3444  S SG  . CYS A 1 452 ? 24.954  18.576  70.287  1.00 72.12  ? 527  CYS A SG  1 
ATOM   3445  N N   . THR A 1 453 ? 26.944  16.093  73.984  1.00 64.12  ? 528  THR A N   1 
ATOM   3446  C CA  . THR A 1 453 ? 27.964  15.369  74.736  1.00 60.32  ? 528  THR A CA  1 
ATOM   3447  C C   . THR A 1 453 ? 27.518  13.942  75.031  1.00 65.03  ? 528  THR A C   1 
ATOM   3448  O O   . THR A 1 453 ? 28.317  13.001  74.934  1.00 75.14  ? 528  THR A O   1 
ATOM   3449  C CB  . THR A 1 453 ? 28.298  16.107  76.032  1.00 58.11  ? 528  THR A CB  1 
ATOM   3450  O OG1 . THR A 1 453 ? 27.125  16.201  76.848  1.00 66.32  ? 528  THR A OG1 1 
ATOM   3451  C CG2 . THR A 1 453 ? 28.821  17.503  75.726  1.00 59.55  ? 528  THR A CG2 1 
ATOM   3452  N N   . ILE A 1 454 ? 26.241  13.759  75.376  1.00 64.55  ? 529  ILE A N   1 
ATOM   3453  C CA  . ILE A 1 454 ? 25.724  12.416  75.619  1.00 66.25  ? 529  ILE A CA  1 
ATOM   3454  C C   . ILE A 1 454 ? 25.856  11.563  74.366  1.00 67.28  ? 529  ILE A C   1 
ATOM   3455  O O   . ILE A 1 454 ? 26.234  10.387  74.433  1.00 63.56  ? 529  ILE A O   1 
ATOM   3456  C CB  . ILE A 1 454 ? 24.263  12.483  76.100  1.00 67.68  ? 529  ILE A CB  1 
ATOM   3457  C CG1 . ILE A 1 454 ? 24.205  12.920  77.560  1.00 71.60  ? 529  ILE A CG1 1 
ATOM   3458  C CG2 . ILE A 1 454 ? 23.572  11.137  75.924  1.00 63.43  ? 529  ILE A CG2 1 
ATOM   3459  C CD1 . ILE A 1 454 ? 22.979  13.727  77.887  1.00 76.17  ? 529  ILE A CD1 1 
ATOM   3460  N N   . ARG A 1 455 ? 25.552  12.142  73.203  1.00 57.29  ? 530  ARG A N   1 
ATOM   3461  C CA  . ARG A 1 455 ? 25.616  11.371  71.967  1.00 60.67  ? 530  ARG A CA  1 
ATOM   3462  C C   . ARG A 1 455 ? 27.057  11.004  71.631  1.00 73.80  ? 530  ARG A C   1 
ATOM   3463  O O   . ARG A 1 455 ? 27.341  9.856   71.269  1.00 73.41  ? 530  ARG A O   1 
ATOM   3464  C CB  . ARG A 1 455 ? 24.969  12.146  70.813  1.00 69.84  ? 530  ARG A CB  1 
ATOM   3465  C CG  . ARG A 1 455 ? 25.693  11.975  69.479  1.00 86.53  ? 530  ARG A CG  1 
ATOM   3466  C CD  . ARG A 1 455 ? 25.066  12.761  68.327  1.00 81.44  ? 530  ARG A CD  1 
ATOM   3467  N NE  . ARG A 1 455 ? 24.645  14.109  68.688  1.00 86.62  ? 530  ARG A NE  1 
ATOM   3468  C CZ  . ARG A 1 455 ? 23.397  14.553  68.618  1.00 94.30  ? 530  ARG A CZ  1 
ATOM   3469  N NH1 . ARG A 1 455 ? 22.401  13.764  68.249  1.00 95.01  ? 530  ARG A NH1 1 
ATOM   3470  N NH2 . ARG A 1 455 ? 23.145  15.825  68.913  1.00 86.90  ? 530  ARG A NH2 1 
ATOM   3471  N N   . GLN A 1 456 ? 27.983  11.957  71.763  1.00 74.49  ? 531  GLN A N   1 
ATOM   3472  C CA  . GLN A 1 456 ? 29.377  11.661  71.452  1.00 64.37  ? 531  GLN A CA  1 
ATOM   3473  C C   . GLN A 1 456 ? 29.973  10.652  72.425  1.00 70.92  ? 531  GLN A C   1 
ATOM   3474  O O   . GLN A 1 456 ? 30.868  9.887   72.047  1.00 77.49  ? 531  GLN A O   1 
ATOM   3475  C CB  . GLN A 1 456 ? 30.211  12.942  71.437  1.00 72.85  ? 531  GLN A CB  1 
ATOM   3476  C CG  . GLN A 1 456 ? 31.479  12.829  70.601  1.00 71.03  ? 531  GLN A CG  1 
ATOM   3477  C CD  . GLN A 1 456 ? 31.787  14.091  69.820  1.00 60.19  ? 531  GLN A CD  1 
ATOM   3478  O OE1 . GLN A 1 456 ? 30.932  14.962  69.664  1.00 59.78  ? 531  GLN A OE1 1 
ATOM   3479  N NE2 . GLN A 1 456 ? 33.016  14.197  69.329  1.00 61.98  ? 531  GLN A NE2 1 
ATOM   3480  N N   . ALA A 1 457 ? 29.496  10.627  73.672  1.00 71.02  ? 532  ALA A N   1 
ATOM   3481  C CA  . ALA A 1 457 ? 29.997  9.635   74.618  1.00 67.26  ? 532  ALA A CA  1 
ATOM   3482  C C   . ALA A 1 457 ? 29.383  8.260   74.376  1.00 76.37  ? 532  ALA A C   1 
ATOM   3483  O O   . ALA A 1 457 ? 30.077  7.242   74.484  1.00 76.73  ? 532  ALA A O   1 
ATOM   3484  C CB  . ALA A 1 457 ? 29.728  10.095  76.050  1.00 66.83  ? 532  ALA A CB  1 
ATOM   3485  N N   . ALA A 1 458 ? 28.090  8.211   74.044  1.00 59.62  ? 533  ALA A N   1 
ATOM   3486  C CA  . ALA A 1 458 ? 27.415  6.932   73.845  1.00 64.27  ? 533  ALA A CA  1 
ATOM   3487  C C   . ALA A 1 458 ? 27.930  6.224   72.600  1.00 69.86  ? 533  ALA A C   1 
ATOM   3488  O O   . ALA A 1 458 ? 28.256  5.032   72.642  1.00 87.94  ? 533  ALA A O   1 
ATOM   3489  C CB  . ALA A 1 458 ? 25.905  7.143   73.759  1.00 74.83  ? 533  ALA A CB  1 
ATOM   3490  N N   . GLU A 1 459 ? 27.992  6.936   71.477  1.00 58.58  ? 534  GLU A N   1 
ATOM   3491  C CA  . GLU A 1 459 ? 28.614  6.438   70.254  1.00 74.43  ? 534  GLU A CA  1 
ATOM   3492  C C   . GLU A 1 459 ? 29.938  7.176   70.077  1.00 83.67  ? 534  GLU A C   1 
ATOM   3493  O O   . GLU A 1 459 ? 29.957  8.388   69.836  1.00 98.46  ? 534  GLU A O   1 
ATOM   3494  C CB  . GLU A 1 459 ? 27.691  6.611   69.044  1.00 73.64  ? 534  GLU A CB  1 
ATOM   3495  C CG  . GLU A 1 459 ? 27.185  8.030   68.789  1.00 74.29  ? 534  GLU A CG  1 
ATOM   3496  C CD  . GLU A 1 459 ? 25.906  8.064   67.976  1.00 85.71  ? 534  GLU A CD  1 
ATOM   3497  O OE1 . GLU A 1 459 ? 25.069  7.154   68.147  1.00 89.91  ? 534  GLU A OE1 1 
ATOM   3498  O OE2 . GLU A 1 459 ? 25.739  8.999   67.163  1.00 83.94  ? 534  GLU A OE2 1 
ATOM   3499  N N   . CYS A 1 460 ? 31.045  6.447   70.215  1.00 72.45  ? 535  CYS A N   1 
ATOM   3500  C CA  . CYS A 1 460 ? 32.376  7.050   70.170  1.00 73.88  ? 535  CYS A CA  1 
ATOM   3501  C C   . CYS A 1 460 ? 32.805  7.317   68.724  1.00 83.44  ? 535  CYS A C   1 
ATOM   3502  O O   . CYS A 1 460 ? 33.802  6.791   68.228  1.00 102.36 ? 535  CYS A O   1 
ATOM   3503  C CB  . CYS A 1 460 ? 33.380  6.159   70.894  1.00 64.74  ? 535  CYS A CB  1 
ATOM   3504  S SG  . CYS A 1 460 ? 33.523  6.475   72.668  1.00 117.88 ? 535  CYS A SG  1 
ATOM   3505  N N   . HIS A 1 461 ? 32.026  8.161   68.046  1.00 62.79  ? 536  HIS A N   1 
ATOM   3506  C CA  . HIS A 1 461 ? 32.305  8.559   66.676  1.00 75.82  ? 536  HIS A CA  1 
ATOM   3507  C C   . HIS A 1 461 ? 31.876  10.006  66.474  1.00 80.88  ? 536  HIS A C   1 
ATOM   3508  O O   . HIS A 1 461 ? 30.858  10.440  67.033  1.00 84.58  ? 536  HIS A O   1 
ATOM   3509  C CB  . HIS A 1 461 ? 31.600  7.642   65.659  1.00 93.53  ? 536  HIS A CB  1 
ATOM   3510  C CG  . HIS A 1 461 ? 30.171  8.003   65.390  1.00 104.54 ? 536  HIS A CG  1 
ATOM   3511  N ND1 . HIS A 1 461 ? 29.801  8.947   64.456  1.00 123.78 ? 536  HIS A ND1 1 
ATOM   3512  C CD2 . HIS A 1 461 ? 29.021  7.533   65.926  1.00 102.25 ? 536  HIS A CD2 1 
ATOM   3513  C CE1 . HIS A 1 461 ? 28.484  9.045   64.432  1.00 137.38 ? 536  HIS A CE1 1 
ATOM   3514  N NE2 . HIS A 1 461 ? 27.986  8.199   65.315  1.00 127.63 ? 536  HIS A NE2 1 
ATOM   3515  N N   . PRO A 1 462 ? 32.633  10.767  65.693  1.00 76.51  ? 537  PRO A N   1 
ATOM   3516  C CA  . PRO A 1 462 ? 32.377  12.203  65.567  1.00 75.52  ? 537  PRO A CA  1 
ATOM   3517  C C   . PRO A 1 462 ? 31.135  12.466  64.737  1.00 84.03  ? 537  PRO A C   1 
ATOM   3518  O O   . PRO A 1 462 ? 30.635  11.565  64.046  1.00 89.66  ? 537  PRO A O   1 
ATOM   3519  C CB  . PRO A 1 462 ? 33.643  12.720  64.858  1.00 59.96  ? 537  PRO A CB  1 
ATOM   3520  C CG  . PRO A 1 462 ? 34.665  11.622  65.054  1.00 72.93  ? 537  PRO A CG  1 
ATOM   3521  C CD  . PRO A 1 462 ? 33.855  10.377  64.973  1.00 71.60  ? 537  PRO A CD  1 
ATOM   3522  N N   . PRO A 1 463 ? 30.597  13.685  64.787  1.00 67.11  ? 538  PRO A N   1 
ATOM   3523  C CA  . PRO A 1 463 ? 29.484  14.035  63.900  1.00 69.50  ? 538  PRO A CA  1 
ATOM   3524  C C   . PRO A 1 463 ? 29.917  14.018  62.441  1.00 69.79  ? 538  PRO A C   1 
ATOM   3525  O O   . PRO A 1 463 ? 31.107  14.031  62.116  1.00 79.35  ? 538  PRO A O   1 
ATOM   3526  C CB  . PRO A 1 463 ? 29.098  15.445  64.364  1.00 75.54  ? 538  PRO A CB  1 
ATOM   3527  C CG  . PRO A 1 463 ? 30.376  15.990  64.930  1.00 66.38  ? 538  PRO A CG  1 
ATOM   3528  C CD  . PRO A 1 463 ? 30.957  14.812  65.664  1.00 66.61  ? 538  PRO A CD  1 
ATOM   3529  N N   . VAL A 1 464 ? 28.923  13.979  61.551  1.00 74.23  ? 539  VAL A N   1 
ATOM   3530  C CA  . VAL A 1 464 ? 29.200  13.817  60.129  1.00 75.95  ? 539  VAL A CA  1 
ATOM   3531  C C   . VAL A 1 464 ? 29.957  15.033  59.608  1.00 80.35  ? 539  VAL A C   1 
ATOM   3532  O O   . VAL A 1 464 ? 29.696  16.176  60.008  1.00 84.80  ? 539  VAL A O   1 
ATOM   3533  C CB  . VAL A 1 464 ? 27.895  13.580  59.349  1.00 73.61  ? 539  VAL A CB  1 
ATOM   3534  C CG1 . VAL A 1 464 ? 26.988  14.791  59.433  1.00 84.76  ? 539  VAL A CG1 1 
ATOM   3535  C CG2 . VAL A 1 464 ? 28.190  13.225  57.901  1.00 74.78  ? 539  VAL A CG2 1 
ATOM   3536  N N   . GLY A 1 465 ? 30.917  14.788  58.718  1.00 89.43  ? 540  GLY A N   1 
ATOM   3537  C CA  . GLY A 1 465 ? 31.812  15.819  58.250  1.00 90.20  ? 540  GLY A CA  1 
ATOM   3538  C C   . GLY A 1 465 ? 33.085  15.966  59.055  1.00 77.28  ? 540  GLY A C   1 
ATOM   3539  O O   . GLY A 1 465 ? 33.968  16.736  58.654  1.00 87.99  ? 540  GLY A O   1 
ATOM   3540  N N   . ARG A 1 466 ? 33.208  15.257  60.173  1.00 68.58  ? 541  ARG A N   1 
ATOM   3541  C CA  . ARG A 1 466 ? 34.400  15.294  61.011  1.00 85.13  ? 541  ARG A CA  1 
ATOM   3542  C C   . ARG A 1 466 ? 35.103  13.951  61.106  1.00 83.00  ? 541  ARG A C   1 
ATOM   3543  O O   . ARG A 1 466 ? 36.336  13.900  61.071  1.00 91.72  ? 541  ARG A O   1 
ATOM   3544  C CB  . ARG A 1 466 ? 34.036  15.789  62.420  1.00 69.74  ? 541  ARG A CB  1 
ATOM   3545  C CG  . ARG A 1 466 ? 33.545  17.232  62.466  1.00 75.67  ? 541  ARG A CG  1 
ATOM   3546  C CD  . ARG A 1 466 ? 34.651  18.206  62.079  1.00 63.99  ? 541  ARG A CD  1 
ATOM   3547  N NE  . ARG A 1 466 ? 34.268  19.602  62.265  1.00 63.31  ? 541  ARG A NE  1 
ATOM   3548  C CZ  . ARG A 1 466 ? 34.261  20.232  63.432  1.00 63.37  ? 541  ARG A CZ  1 
ATOM   3549  N NH1 . ARG A 1 466 ? 34.598  19.615  64.554  1.00 49.84  ? 541  ARG A NH1 1 
ATOM   3550  N NH2 . ARG A 1 466 ? 33.910  21.514  63.476  1.00 61.64  ? 541  ARG A NH2 1 
ATOM   3551  N N   . GLY A 1 467 ? 34.352  12.857  61.221  1.00 83.75  ? 542  GLY A N   1 
ATOM   3552  C CA  . GLY A 1 467 ? 34.940  11.535  61.246  1.00 95.93  ? 542  GLY A CA  1 
ATOM   3553  C C   . GLY A 1 467 ? 34.077  10.558  60.473  1.00 91.68  ? 542  GLY A C   1 
ATOM   3554  O O   . GLY A 1 467 ? 32.899  10.810  60.209  1.00 98.17  ? 542  GLY A O   1 
ATOM   3555  N N   . THR A 1 468 ? 34.688  9.424   60.120  1.00 92.71  ? 543  THR A N   1 
ATOM   3556  C CA  . THR A 1 468 ? 33.997  8.449   59.284  1.00 100.16 ? 543  THR A CA  1 
ATOM   3557  C C   . THR A 1 468 ? 32.803  7.852   60.020  1.00 112.82 ? 543  THR A C   1 
ATOM   3558  O O   . THR A 1 468 ? 31.760  7.577   59.413  1.00 136.37 ? 543  THR A O   1 
ATOM   3559  C CB  . THR A 1 468 ? 34.955  7.331   58.861  1.00 98.79  ? 543  THR A CB  1 
ATOM   3560  O OG1 . THR A 1 468 ? 34.260  6.403   58.024  1.00 121.17 ? 543  THR A OG1 1 
ATOM   3561  C CG2 . THR A 1 468 ? 35.437  6.557   60.075  1.00 105.70 ? 543  THR A CG2 1 
ATOM   3562  N N   . GLY A 1 469 ? 32.933  7.664   61.336  1.00 107.65 ? 544  GLY A N   1 
ATOM   3563  C CA  . GLY A 1 469 ? 31.955  6.955   62.133  1.00 117.13 ? 544  GLY A CA  1 
ATOM   3564  C C   . GLY A 1 469 ? 31.958  5.451   61.974  1.00 118.36 ? 544  GLY A C   1 
ATOM   3565  O O   . GLY A 1 469 ? 31.225  4.770   62.703  1.00 110.09 ? 544  GLY A O   1 
ATOM   3566  N N   . LYS A 1 470 ? 32.736  4.909   61.042  1.00 117.13 ? 545  LYS A N   1 
ATOM   3567  C CA  . LYS A 1 470 ? 32.849  3.470   60.825  1.00 120.04 ? 545  LYS A CA  1 
ATOM   3568  C C   . LYS A 1 470 ? 34.304  3.068   61.048  1.00 113.56 ? 545  LYS A C   1 
ATOM   3569  O O   . LYS A 1 470 ? 35.015  2.689   60.113  1.00 125.31 ? 545  LYS A O   1 
ATOM   3570  C CB  . LYS A 1 470 ? 32.357  3.087   59.426  1.00 129.06 ? 545  LYS A CB  1 
ATOM   3571  C CG  . LYS A 1 470 ? 30.853  2.887   59.338  1.00 133.13 ? 545  LYS A CG  1 
ATOM   3572  C CD  . LYS A 1 470 ? 30.292  3.480   58.057  1.00 141.48 ? 545  LYS A CD  1 
ATOM   3573  C CE  . LYS A 1 470 ? 30.576  4.972   57.977  1.00 152.89 ? 545  LYS A CE  1 
ATOM   3574  N NZ  . LYS A 1 470 ? 29.994  5.712   59.133  1.00 166.25 ? 545  LYS A NZ  1 
ATOM   3575  N N   . ARG A 1 471 ? 34.746  3.174   62.298  1.00 109.41 ? 546  ARG A N   1 
ATOM   3576  C CA  . ARG A 1 471 ? 36.093  2.803   62.703  1.00 83.59  ? 546  ARG A CA  1 
ATOM   3577  C C   . ARG A 1 471 ? 35.996  1.890   63.914  1.00 78.34  ? 546  ARG A C   1 
ATOM   3578  O O   . ARG A 1 471 ? 35.251  2.185   64.855  1.00 90.81  ? 546  ARG A O   1 
ATOM   3579  C CB  . ARG A 1 471 ? 36.931  4.048   63.019  1.00 81.46  ? 546  ARG A CB  1 
ATOM   3580  C CG  . ARG A 1 471 ? 38.300  3.759   63.601  1.00 92.47  ? 546  ARG A CG  1 
ATOM   3581  C CD  . ARG A 1 471 ? 38.853  4.968   64.337  1.00 78.55  ? 546  ARG A CD  1 
ATOM   3582  N NE  . ARG A 1 471 ? 38.669  4.848   65.777  1.00 53.59  ? 546  ARG A NE  1 
ATOM   3583  C CZ  . ARG A 1 471 ? 38.134  5.790   66.540  1.00 75.02  ? 546  ARG A CZ  1 
ATOM   3584  N NH1 . ARG A 1 471 ? 37.768  6.959   66.041  1.00 94.27  ? 546  ARG A NH1 1 
ATOM   3585  N NH2 . ARG A 1 471 ? 37.948  5.549   67.832  1.00 69.23  ? 546  ARG A NH2 1 
ATOM   3586  N N   . VAL A 1 472 ? 36.732  0.776   63.881  1.00 62.08  ? 547  VAL A N   1 
ATOM   3587  C CA  . VAL A 1 472 ? 36.681  -0.179  64.981  1.00 72.49  ? 547  VAL A CA  1 
ATOM   3588  C C   . VAL A 1 472 ? 37.132  0.502   66.263  1.00 71.74  ? 547  VAL A C   1 
ATOM   3589  O O   . VAL A 1 472 ? 38.212  1.104   66.324  1.00 67.20  ? 547  VAL A O   1 
ATOM   3590  C CB  . VAL A 1 472 ? 37.539  -1.413  64.669  1.00 66.35  ? 547  VAL A CB  1 
ATOM   3591  C CG1 . VAL A 1 472 ? 37.429  -2.431  65.798  1.00 71.70  ? 547  VAL A CG1 1 
ATOM   3592  C CG2 . VAL A 1 472 ? 37.118  -2.033  63.347  1.00 60.87  ? 547  VAL A CG2 1 
ATOM   3593  N N   . LEU A 1 473 ? 36.297  0.423   67.291  1.00 73.02  ? 548  LEU A N   1 
ATOM   3594  C CA  . LEU A 1 473 ? 36.617  1.064   68.556  1.00 77.42  ? 548  LEU A CA  1 
ATOM   3595  C C   . LEU A 1 473 ? 37.779  0.347   69.232  1.00 76.02  ? 548  LEU A C   1 
ATOM   3596  O O   . LEU A 1 473 ? 37.907  -0.878  69.150  1.00 78.84  ? 548  LEU A O   1 
ATOM   3597  C CB  . LEU A 1 473 ? 35.394  1.063   69.471  1.00 73.81  ? 548  LEU A CB  1 
ATOM   3598  C CG  . LEU A 1 473 ? 34.421  2.237   69.364  1.00 60.29  ? 548  LEU A CG  1 
ATOM   3599  C CD1 . LEU A 1 473 ? 33.467  2.237   70.549  1.00 72.23  ? 548  LEU A CD1 1 
ATOM   3600  C CD2 . LEU A 1 473 ? 35.165  3.558   69.264  1.00 65.74  ? 548  LEU A CD2 1 
ATOM   3601  N N   . THR A 1 474 ? 38.637  1.118   69.891  1.00 70.77  ? 549  THR A N   1 
ATOM   3602  C CA  . THR A 1 474 ? 39.705  0.516   70.671  1.00 74.38  ? 549  THR A CA  1 
ATOM   3603  C C   . THR A 1 474 ? 39.127  -0.128  71.924  1.00 73.45  ? 549  THR A C   1 
ATOM   3604  O O   . THR A 1 474 ? 38.055  0.250   72.404  1.00 84.08  ? 549  THR A O   1 
ATOM   3605  C CB  . THR A 1 474 ? 40.755  1.561   71.053  1.00 70.54  ? 549  THR A CB  1 
ATOM   3606  O OG1 . THR A 1 474 ? 41.000  2.424   69.936  1.00 82.68  ? 549  THR A OG1 1 
ATOM   3607  C CG2 . THR A 1 474 ? 42.061  0.883   71.446  1.00 77.70  ? 549  THR A CG2 1 
ATOM   3608  N N   . ALA A 1 475 ? 39.841  -1.129  72.444  1.00 68.96  ? 550  ALA A N   1 
ATOM   3609  C CA  . ALA A 1 475 ? 39.437  -1.754  73.698  1.00 69.48  ? 550  ALA A CA  1 
ATOM   3610  C C   . ALA A 1 475 ? 39.268  -0.708  74.794  1.00 71.56  ? 550  ALA A C   1 
ATOM   3611  O O   . ALA A 1 475 ? 38.249  -0.681  75.496  1.00 79.89  ? 550  ALA A O   1 
ATOM   3612  C CB  . ALA A 1 475 ? 40.462  -2.812  74.105  1.00 89.96  ? 550  ALA A CB  1 
ATOM   3613  N N   . LYS A 1 476 ? 40.264  0.171   74.943  1.00 73.27  ? 551  LYS A N   1 
ATOM   3614  C CA  . LYS A 1 476 ? 40.131  1.306   75.850  1.00 80.71  ? 551  LYS A CA  1 
ATOM   3615  C C   . LYS A 1 476 ? 38.907  2.144   75.507  1.00 74.70  ? 551  LYS A C   1 
ATOM   3616  O O   . LYS A 1 476 ? 38.160  2.565   76.400  1.00 80.32  ? 551  LYS A O   1 
ATOM   3617  C CB  . LYS A 1 476 ? 41.391  2.169   75.798  1.00 86.24  ? 551  LYS A CB  1 
ATOM   3618  C CG  . LYS A 1 476 ? 41.452  3.241   76.871  1.00 93.74  ? 551  LYS A CG  1 
ATOM   3619  C CD  . LYS A 1 476 ? 42.789  3.958   76.856  1.00 101.52 ? 551  LYS A CD  1 
ATOM   3620  C CE  . LYS A 1 476 ? 42.809  5.107   77.849  1.00 102.31 ? 551  LYS A CE  1 
ATOM   3621  N NZ  . LYS A 1 476 ? 44.001  5.977   77.668  1.00 100.87 ? 551  LYS A NZ  1 
ATOM   3622  N N   . GLU A 1 477 ? 38.690  2.399   74.217  1.00 73.49  ? 552  GLU A N   1 
ATOM   3623  C CA  . GLU A 1 477 ? 37.551  3.214   73.814  1.00 69.55  ? 552  GLU A CA  1 
ATOM   3624  C C   . GLU A 1 477 ? 36.236  2.508   74.110  1.00 77.06  ? 552  GLU A C   1 
ATOM   3625  O O   . GLU A 1 477 ? 35.268  3.147   74.531  1.00 75.11  ? 552  GLU A O   1 
ATOM   3626  C CB  . GLU A 1 477 ? 37.654  3.559   72.333  1.00 62.34  ? 552  GLU A CB  1 
ATOM   3627  C CG  . GLU A 1 477 ? 38.668  4.631   72.030  1.00 73.87  ? 552  GLU A CG  1 
ATOM   3628  C CD  . GLU A 1 477 ? 38.670  4.995   70.573  1.00 68.26  ? 552  GLU A CD  1 
ATOM   3629  O OE1 . GLU A 1 477 ? 38.748  4.070   69.737  1.00 61.86  ? 552  GLU A OE1 1 
ATOM   3630  O OE2 . GLU A 1 477 ? 38.585  6.199   70.255  1.00 65.91  ? 552  GLU A OE2 1 
ATOM   3631  N N   . LYS A 1 478 ? 36.186  1.188   73.907  1.00 75.05  ? 553  LYS A N   1 
ATOM   3632  C CA  . LYS A 1 478 ? 34.967  0.445   74.213  1.00 61.63  ? 553  LYS A CA  1 
ATOM   3633  C C   . LYS A 1 478 ? 34.666  0.468   75.706  1.00 70.17  ? 553  LYS A C   1 
ATOM   3634  O O   . LYS A 1 478 ? 33.510  0.636   76.109  1.00 90.92  ? 553  LYS A O   1 
ATOM   3635  C CB  . LYS A 1 478 ? 35.084  -0.992  73.700  1.00 63.45  ? 553  LYS A CB  1 
ATOM   3636  C CG  . LYS A 1 478 ? 35.047  -1.092  72.185  1.00 64.24  ? 553  LYS A CG  1 
ATOM   3637  C CD  . LYS A 1 478 ? 35.011  -2.528  71.697  1.00 69.47  ? 553  LYS A CD  1 
ATOM   3638  C CE  . LYS A 1 478 ? 36.379  -2.941  71.183  1.00 86.68  ? 553  LYS A CE  1 
ATOM   3639  N NZ  . LYS A 1 478 ? 36.594  -4.413  71.224  1.00 90.84  ? 553  LYS A NZ  1 
ATOM   3640  N N   . LYS A 1 479 ? 35.693  0.319   76.545  1.00 76.49  ? 554  LYS A N   1 
ATOM   3641  C CA  . LYS A 1 479 ? 35.466  0.368   77.987  1.00 67.37  ? 554  LYS A CA  1 
ATOM   3642  C C   . LYS A 1 479 ? 35.022  1.759   78.433  1.00 72.70  ? 554  LYS A C   1 
ATOM   3643  O O   . LYS A 1 479 ? 34.097  1.893   79.248  1.00 91.21  ? 554  LYS A O   1 
ATOM   3644  C CB  . LYS A 1 479 ? 36.728  -0.079  78.726  1.00 82.09  ? 554  LYS A CB  1 
ATOM   3645  C CG  . LYS A 1 479 ? 37.055  -1.558  78.517  1.00 119.37 ? 554  LYS A CG  1 
ATOM   3646  C CD  . LYS A 1 479 ? 38.380  -1.966  79.151  1.00 129.65 ? 554  LYS A CD  1 
ATOM   3647  C CE  . LYS A 1 479 ? 39.546  -1.804  78.184  1.00 109.51 ? 554  LYS A CE  1 
ATOM   3648  N NZ  . LYS A 1 479 ? 40.449  -0.673  78.541  1.00 112.50 ? 554  LYS A NZ  1 
ATOM   3649  N N   . THR A 1 480 ? 35.657  2.808   77.899  1.00 84.13  ? 555  THR A N   1 
ATOM   3650  C CA  . THR A 1 480 ? 35.241  4.172   78.218  1.00 81.59  ? 555  THR A CA  1 
ATOM   3651  C C   . THR A 1 480 ? 33.805  4.425   77.779  1.00 80.37  ? 555  THR A C   1 
ATOM   3652  O O   . THR A 1 480 ? 33.023  5.048   78.507  1.00 84.56  ? 555  THR A O   1 
ATOM   3653  C CB  . THR A 1 480 ? 36.176  5.181   77.551  1.00 72.92  ? 555  THR A CB  1 
ATOM   3654  O OG1 . THR A 1 480 ? 37.538  4.823   77.811  1.00 81.17  ? 555  THR A OG1 1 
ATOM   3655  C CG2 . THR A 1 480 ? 35.909  6.584   78.082  1.00 71.39  ? 555  THR A CG2 1 
ATOM   3656  N N   . GLN A 1 481 ? 33.446  3.955   76.581  1.00 85.84  ? 556  GLN A N   1 
ATOM   3657  C CA  . GLN A 1 481 ? 32.092  4.127   76.072  1.00 86.63  ? 556  GLN A CA  1 
ATOM   3658  C C   . GLN A 1 481 ? 31.078  3.400   76.943  1.00 84.94  ? 556  GLN A C   1 
ATOM   3659  O O   . GLN A 1 481 ? 29.998  3.930   77.220  1.00 80.88  ? 556  GLN A O   1 
ATOM   3660  C CB  . GLN A 1 481 ? 32.023  3.624   74.631  1.00 76.05  ? 556  GLN A CB  1 
ATOM   3661  C CG  . GLN A 1 481 ? 30.626  3.271   74.155  1.00 65.46  ? 556  GLN A CG  1 
ATOM   3662  C CD  . GLN A 1 481 ? 30.637  2.524   72.837  1.00 74.79  ? 556  GLN A CD  1 
ATOM   3663  O OE1 . GLN A 1 481 ? 31.032  1.359   72.775  1.00 66.80  ? 556  GLN A OE1 1 
ATOM   3664  N NE2 . GLN A 1 481 ? 30.195  3.187   71.775  1.00 69.74  ? 556  GLN A NE2 1 
ATOM   3665  N N   . LEU A 1 482 ? 31.407  2.184   77.384  1.00 82.25  ? 557  LEU A N   1 
ATOM   3666  C CA  . LEU A 1 482 ? 30.498  1.447   78.256  1.00 78.98  ? 557  LEU A CA  1 
ATOM   3667  C C   . LEU A 1 482 ? 30.306  2.171   79.583  1.00 83.50  ? 557  LEU A C   1 
ATOM   3668  O O   . LEU A 1 482 ? 29.184  2.256   80.099  1.00 87.84  ? 557  LEU A O   1 
ATOM   3669  C CB  . LEU A 1 482 ? 31.026  0.031   78.488  1.00 76.24  ? 557  LEU A CB  1 
ATOM   3670  C CG  . LEU A 1 482 ? 30.987  -0.943  77.304  1.00 99.70  ? 557  LEU A CG  1 
ATOM   3671  C CD1 . LEU A 1 482 ? 30.852  -2.376  77.796  1.00 102.16 ? 557  LEU A CD1 1 
ATOM   3672  C CD2 . LEU A 1 482 ? 29.868  -0.599  76.329  1.00 116.67 ? 557  LEU A CD2 1 
ATOM   3673  N N   . ASP A 1 483 ? 31.391  2.709   80.146  1.00 83.80  ? 558  ASP A N   1 
ATOM   3674  C CA  . ASP A 1 483 ? 31.273  3.438   81.405  1.00 86.29  ? 558  ASP A CA  1 
ATOM   3675  C C   . ASP A 1 483 ? 30.427  4.696   81.233  1.00 80.55  ? 558  ASP A C   1 
ATOM   3676  O O   . ASP A 1 483 ? 29.545  4.981   82.057  1.00 86.96  ? 558  ASP A O   1 
ATOM   3677  C CB  . ASP A 1 483 ? 32.662  3.783   81.941  1.00 93.62  ? 558  ASP A CB  1 
ATOM   3678  C CG  . ASP A 1 483 ? 32.769  3.596   83.442  1.00 126.28 ? 558  ASP A CG  1 
ATOM   3679  O OD1 . ASP A 1 483 ? 31.977  4.217   84.182  1.00 131.23 ? 558  ASP A OD1 1 
ATOM   3680  O OD2 . ASP A 1 483 ? 33.648  2.823   83.881  1.00 128.85 ? 558  ASP A OD2 1 
ATOM   3681  N N   . ASP A 1 484 ? 30.675  5.457   80.161  1.00 78.24  ? 559  ASP A N   1 
ATOM   3682  C CA  . ASP A 1 484 ? 29.868  6.644   79.889  1.00 80.41  ? 559  ASP A CA  1 
ATOM   3683  C C   . ASP A 1 484 ? 28.403  6.282   79.687  1.00 83.40  ? 559  ASP A C   1 
ATOM   3684  O O   . ASP A 1 484 ? 27.514  7.000   80.153  1.00 81.17  ? 559  ASP A O   1 
ATOM   3685  C CB  . ASP A 1 484 ? 30.393  7.393   78.661  1.00 75.81  ? 559  ASP A CB  1 
ATOM   3686  C CG  . ASP A 1 484 ? 31.870  7.717   78.748  1.00 74.03  ? 559  ASP A CG  1 
ATOM   3687  O OD1 . ASP A 1 484 ? 32.358  7.988   79.864  1.00 83.32  ? 559  ASP A OD1 1 
ATOM   3688  O OD2 . ASP A 1 484 ? 32.542  7.713   77.694  1.00 85.91  ? 559  ASP A OD2 1 
ATOM   3689  N N   . ARG A 1 485 ? 28.129  5.176   78.991  1.00 79.53  ? 560  ARG A N   1 
ATOM   3690  C CA  . ARG A 1 485 ? 26.747  4.792   78.725  1.00 81.60  ? 560  ARG A CA  1 
ATOM   3691  C C   . ARG A 1 485 ? 26.031  4.390   80.006  1.00 82.04  ? 560  ARG A C   1 
ATOM   3692  O O   . ARG A 1 485 ? 24.873  4.767   80.217  1.00 82.23  ? 560  ARG A O   1 
ATOM   3693  C CB  . ARG A 1 485 ? 26.700  3.656   77.704  1.00 76.64  ? 560  ARG A CB  1 
ATOM   3694  C CG  . ARG A 1 485 ? 26.950  4.108   76.280  1.00 71.02  ? 560  ARG A CG  1 
ATOM   3695  C CD  . ARG A 1 485 ? 26.888  2.945   75.306  1.00 89.71  ? 560  ARG A CD  1 
ATOM   3696  N NE  . ARG A 1 485 ? 26.198  3.315   74.077  1.00 89.61  ? 560  ARG A NE  1 
ATOM   3697  C CZ  . ARG A 1 485 ? 24.886  3.473   73.978  1.00 96.91  ? 560  ARG A CZ  1 
ATOM   3698  N NH1 . ARG A 1 485 ? 24.085  3.263   75.010  1.00 102.26 ? 560  ARG A NH1 1 
ATOM   3699  N NH2 . ARG A 1 485 ? 24.363  3.849   72.814  1.00 96.36  ? 560  ARG A NH2 1 
ATOM   3700  N N   . THR A 1 486 ? 26.701  3.628   80.874  1.00 79.04  ? 561  THR A N   1 
ATOM   3701  C CA  . THR A 1 486 ? 26.091  3.281   82.153  1.00 82.87  ? 561  THR A CA  1 
ATOM   3702  C C   . THR A 1 486 ? 25.830  4.525   82.994  1.00 83.70  ? 561  THR A C   1 
ATOM   3703  O O   . THR A 1 486 ? 24.753  4.664   83.589  1.00 86.88  ? 561  THR A O   1 
ATOM   3704  C CB  . THR A 1 486 ? 26.969  2.287   82.913  1.00 60.05  ? 561  THR A CB  1 
ATOM   3705  O OG1 . THR A 1 486 ? 28.290  2.824   83.054  1.00 100.63 ? 561  THR A OG1 1 
ATOM   3706  C CG2 . THR A 1 486 ? 27.033  0.958   82.172  1.00 56.21  ? 561  THR A CG2 1 
ATOM   3707  N N   . ARG A 1 487 ? 26.797  5.446   83.049  1.00 81.52  ? 562  ARG A N   1 
ATOM   3708  C CA  . ARG A 1 487 ? 26.590  6.672   83.815  1.00 88.48  ? 562  ARG A CA  1 
ATOM   3709  C C   . ARG A 1 487 ? 25.429  7.484   83.253  1.00 84.36  ? 562  ARG A C   1 
ATOM   3710  O O   . ARG A 1 487 ? 24.580  7.974   84.009  1.00 82.45  ? 562  ARG A O   1 
ATOM   3711  C CB  . ARG A 1 487 ? 27.867  7.511   83.832  1.00 95.03  ? 562  ARG A CB  1 
ATOM   3712  C CG  . ARG A 1 487 ? 27.908  8.516   84.968  1.00 100.14 ? 562  ARG A CG  1 
ATOM   3713  C CD  . ARG A 1 487 ? 28.886  9.642   84.696  1.00 87.79  ? 562  ARG A CD  1 
ATOM   3714  N NE  . ARG A 1 487 ? 28.266  10.945  84.913  1.00 120.84 ? 562  ARG A NE  1 
ATOM   3715  C CZ  . ARG A 1 487 ? 28.924  12.096  84.920  1.00 117.41 ? 562  ARG A CZ  1 
ATOM   3716  N NH1 . ARG A 1 487 ? 30.229  12.146  84.714  1.00 109.32 ? 562  ARG A NH1 1 
ATOM   3717  N NH2 . ARG A 1 487 ? 28.256  13.224  85.145  1.00 128.90 ? 562  ARG A NH2 1 
ATOM   3718  N N   . ILE A 1 488 ? 25.378  7.635   81.926  1.00 85.66  ? 563  ILE A N   1 
ATOM   3719  C CA  . ILE A 1 488 ? 24.294  8.372   81.283  1.00 89.87  ? 563  ILE A CA  1 
ATOM   3720  C C   . ILE A 1 488 ? 22.954  7.736   81.617  1.00 82.26  ? 563  ILE A C   1 
ATOM   3721  O O   . ILE A 1 488 ? 21.996  8.421   81.994  1.00 79.94  ? 563  ILE A O   1 
ATOM   3722  C CB  . ILE A 1 488 ? 24.517  8.433   79.760  1.00 81.11  ? 563  ILE A CB  1 
ATOM   3723  C CG1 . ILE A 1 488 ? 25.615  9.435   79.407  1.00 78.13  ? 563  ILE A CG1 1 
ATOM   3724  C CG2 . ILE A 1 488 ? 23.224  8.780   79.035  1.00 75.14  ? 563  ILE A CG2 1 
ATOM   3725  C CD1 . ILE A 1 488 ? 26.181  9.240   78.016  1.00 78.27  ? 563  ILE A CD1 1 
ATOM   3726  N N   . THR A 1 489 ? 22.869  6.411   81.481  1.00 84.42  ? 564  THR A N   1 
ATOM   3727  C CA  . THR A 1 489 ? 21.616  5.715   81.740  1.00 83.70  ? 564  THR A CA  1 
ATOM   3728  C C   . THR A 1 489 ? 21.163  5.923   83.178  1.00 84.49  ? 564  THR A C   1 
ATOM   3729  O O   . THR A 1 489 ? 20.024  6.326   83.425  1.00 84.66  ? 564  THR A O   1 
ATOM   3730  C CB  . THR A 1 489 ? 21.765  4.225   81.430  1.00 80.11  ? 564  THR A CB  1 
ATOM   3731  O OG1 . THR A 1 489 ? 22.369  4.059   80.141  1.00 98.52  ? 564  THR A OG1 1 
ATOM   3732  C CG2 . THR A 1 489 ? 20.404  3.551   81.430  1.00 72.15  ? 564  THR A CG2 1 
ATOM   3733  N N   . GLU A 1 490 ? 22.053  5.679   84.146  1.00 78.58  ? 565  GLU A N   1 
ATOM   3734  C CA  . GLU A 1 490 ? 21.645  5.770   85.547  1.00 79.58  ? 565  GLU A CA  1 
ATOM   3735  C C   . GLU A 1 490 ? 21.339  7.200   85.974  1.00 77.34  ? 565  GLU A C   1 
ATOM   3736  O O   . GLU A 1 490 ? 20.453  7.414   86.808  1.00 81.65  ? 565  GLU A O   1 
ATOM   3737  C CB  . GLU A 1 490 ? 22.717  5.162   86.452  1.00 83.25  ? 565  GLU A CB  1 
ATOM   3738  C CG  . GLU A 1 490 ? 23.170  3.788   86.012  1.00 94.80  ? 565  GLU A CG  1 
ATOM   3739  C CD  . GLU A 1 490 ? 24.133  3.146   86.983  1.00 119.82 ? 565  GLU A CD  1 
ATOM   3740  O OE1 . GLU A 1 490 ? 23.895  1.982   87.364  1.00 157.24 ? 565  GLU A OE1 1 
ATOM   3741  O OE2 . GLU A 1 490 ? 25.130  3.798   87.358  1.00 121.15 ? 565  GLU A OE2 1 
ATOM   3742  N N   . LEU A 1 491 ? 22.038  8.189   85.418  1.00 83.95  ? 566  LEU A N   1 
ATOM   3743  C CA  . LEU A 1 491 ? 21.771  9.573   85.790  1.00 80.76  ? 566  LEU A CA  1 
ATOM   3744  C C   . LEU A 1 491 ? 20.471  10.063  85.161  1.00 85.27  ? 566  LEU A C   1 
ATOM   3745  O O   . LEU A 1 491 ? 19.594  10.615  85.841  1.00 94.73  ? 566  LEU A O   1 
ATOM   3746  C CB  . LEU A 1 491 ? 22.949  10.447  85.359  1.00 90.64  ? 566  LEU A CB  1 
ATOM   3747  C CG  . LEU A 1 491 ? 23.077  11.892  85.838  1.00 97.95  ? 566  LEU A CG  1 
ATOM   3748  C CD1 . LEU A 1 491 ? 23.714  11.945  87.216  1.00 113.33 ? 566  LEU A CD1 1 
ATOM   3749  C CD2 . LEU A 1 491 ? 23.895  12.697  84.835  1.00 99.13  ? 566  LEU A CD2 1 
ATOM   3750  N N   . PHE A 1 492 ? 20.314  9.859   83.858  1.00 83.48  ? 567  PHE A N   1 
ATOM   3751  C CA  . PHE A 1 492 ? 19.175  10.431  83.167  1.00 79.39  ? 567  PHE A CA  1 
ATOM   3752  C C   . PHE A 1 492 ? 17.917  9.578   83.245  1.00 84.23  ? 567  PHE A C   1 
ATOM   3753  O O   . PHE A 1 492 ? 16.843  10.107  82.965  1.00 91.04  ? 567  PHE A O   1 
ATOM   3754  C CB  . PHE A 1 492 ? 19.545  10.723  81.712  1.00 78.94  ? 567  PHE A CB  1 
ATOM   3755  C CG  . PHE A 1 492 ? 20.515  11.855  81.568  1.00 84.85  ? 567  PHE A CG  1 
ATOM   3756  C CD1 . PHE A 1 492 ? 20.108  13.158  81.812  1.00 82.16  ? 567  PHE A CD1 1 
ATOM   3757  C CD2 . PHE A 1 492 ? 21.837  11.623  81.234  1.00 82.48  ? 567  PHE A CD2 1 
ATOM   3758  C CE1 . PHE A 1 492 ? 20.992  14.210  81.700  1.00 72.30  ? 567  PHE A CE1 1 
ATOM   3759  C CE2 . PHE A 1 492 ? 22.729  12.671  81.124  1.00 86.08  ? 567  PHE A CE2 1 
ATOM   3760  C CZ  . PHE A 1 492 ? 22.305  13.967  81.355  1.00 78.12  ? 567  PHE A CZ  1 
ATOM   3761  N N   . ALA A 1 493 ? 18.000  8.316   83.682  1.00 75.25  ? 568  ALA A N   1 
ATOM   3762  C CA  . ALA A 1 493 ? 16.784  7.565   83.973  1.00 76.16  ? 568  ALA A CA  1 
ATOM   3763  C C   . ALA A 1 493 ? 15.916  8.316   84.969  1.00 83.46  ? 568  ALA A C   1 
ATOM   3764  O O   . ALA A 1 493 ? 14.683  8.294   84.879  1.00 86.35  ? 568  ALA A O   1 
ATOM   3765  C CB  . ALA A 1 493 ? 17.137  6.177   84.507  1.00 64.26  ? 568  ALA A CB  1 
ATOM   3766  N N   . VAL A 1 494 ? 16.548  9.006   85.912  1.00 87.12  ? 569  VAL A N   1 
ATOM   3767  C CA  . VAL A 1 494 ? 15.826  9.851   86.852  1.00 94.47  ? 569  VAL A CA  1 
ATOM   3768  C C   . VAL A 1 494 ? 15.764  11.294  86.366  1.00 87.59  ? 569  VAL A C   1 
ATOM   3769  O O   . VAL A 1 494 ? 14.735  11.957  86.523  1.00 102.37 ? 569  VAL A O   1 
ATOM   3770  C CB  . VAL A 1 494 ? 16.473  9.754   88.248  1.00 81.23  ? 569  VAL A CB  1 
ATOM   3771  C CG1 . VAL A 1 494 ? 15.608  10.460  89.286  1.00 89.71  ? 569  VAL A CG1 1 
ATOM   3772  C CG2 . VAL A 1 494 ? 16.705  8.297   88.626  1.00 66.61  ? 569  VAL A CG2 1 
ATOM   3773  N N   . ALA A 1 495 ? 16.840  11.801  85.754  1.00 67.37  ? 570  ALA A N   1 
ATOM   3774  C CA  . ALA A 1 495 ? 16.863  13.216  85.385  1.00 82.31  ? 570  ALA A CA  1 
ATOM   3775  C C   . ALA A 1 495 ? 15.852  13.549  84.287  1.00 85.18  ? 570  ALA A C   1 
ATOM   3776  O O   . ALA A 1 495 ? 15.247  14.628  84.305  1.00 78.26  ? 570  ALA A O   1 
ATOM   3777  C CB  . ALA A 1 495 ? 18.273  13.621  84.954  1.00 84.36  ? 570  ALA A CB  1 
ATOM   3778  N N   . LEU A 1 496 ? 15.642  12.638  83.329  1.00 72.89  ? 571  LEU A N   1 
ATOM   3779  C CA  . LEU A 1 496 ? 14.887  12.899  82.107  1.00 70.80  ? 571  LEU A CA  1 
ATOM   3780  C C   . LEU A 1 496 ? 13.395  13.097  82.352  1.00 85.11  ? 571  LEU A C   1 
ATOM   3781  O O   . LEU A 1 496 ? 12.802  13.988  81.730  1.00 84.41  ? 571  LEU A O   1 
ATOM   3782  C CB  . LEU A 1 496 ? 15.090  11.763  81.100  1.00 65.46  ? 571  LEU A CB  1 
ATOM   3783  C CG  . LEU A 1 496 ? 14.531  12.008  79.697  1.00 61.77  ? 571  LEU A CG  1 
ATOM   3784  C CD1 . LEU A 1 496 ? 14.904  13.393  79.196  1.00 61.63  ? 571  LEU A CD1 1 
ATOM   3785  C CD2 . LEU A 1 496 ? 15.047  10.950  78.768  1.00 59.38  ? 571  LEU A CD2 1 
ATOM   3786  N N   . PRO A 1 497 ? 12.734  12.292  83.195  1.00 79.88  ? 572  PRO A N   1 
ATOM   3787  C CA  . PRO A 1 497 ? 11.331  12.609  83.518  1.00 66.04  ? 572  PRO A CA  1 
ATOM   3788  C C   . PRO A 1 497 ? 11.168  14.015  84.069  1.00 75.11  ? 572  PRO A C   1 
ATOM   3789  O O   . PRO A 1 497 ? 10.287  14.767  83.628  1.00 77.05  ? 572  PRO A O   1 
ATOM   3790  C CB  . PRO A 1 497 ? 10.973  11.532  84.547  1.00 71.32  ? 572  PRO A CB  1 
ATOM   3791  C CG  . PRO A 1 497 ? 11.815  10.376  84.165  1.00 67.13  ? 572  PRO A CG  1 
ATOM   3792  C CD  . PRO A 1 497 ? 13.117  10.958  83.701  1.00 76.56  ? 572  PRO A CD  1 
ATOM   3793  N N   . GLN A 1 498 ? 12.031  14.391  85.014  1.00 76.13  ? 573  GLN A N   1 
ATOM   3794  C CA  . GLN A 1 498 ? 11.996  15.732  85.586  1.00 81.26  ? 573  GLN A CA  1 
ATOM   3795  C C   . GLN A 1 498 ? 12.215  16.792  84.513  1.00 81.61  ? 573  GLN A C   1 
ATOM   3796  O O   . GLN A 1 498 ? 11.450  17.758  84.413  1.00 80.78  ? 573  GLN A O   1 
ATOM   3797  C CB  . GLN A 1 498 ? 13.056  15.849  86.682  1.00 78.84  ? 573  GLN A CB  1 
ATOM   3798  C CG  . GLN A 1 498 ? 13.045  14.688  87.662  1.00 77.72  ? 573  GLN A CG  1 
ATOM   3799  C CD  . GLN A 1 498 ? 14.155  14.770  88.691  1.00 90.74  ? 573  GLN A CD  1 
ATOM   3800  O OE1 . GLN A 1 498 ? 15.048  13.923  88.719  1.00 99.70  ? 573  GLN A OE1 1 
ATOM   3801  N NE2 . GLN A 1 498 ? 14.104  15.786  89.545  1.00 97.09  ? 573  GLN A NE2 1 
ATOM   3802  N N   . LEU A 1 499 ? 13.264  16.624  83.702  1.00 87.26  ? 574  LEU A N   1 
ATOM   3803  C CA  . LEU A 1 499 ? 13.573  17.599  82.660  1.00 83.62  ? 574  LEU A CA  1 
ATOM   3804  C C   . LEU A 1 499 ? 12.415  17.749  81.683  1.00 81.52  ? 574  LEU A C   1 
ATOM   3805  O O   . LEU A 1 499 ? 12.066  18.867  81.286  1.00 71.74  ? 574  LEU A O   1 
ATOM   3806  C CB  . LEU A 1 499 ? 14.841  17.180  81.918  1.00 77.44  ? 574  LEU A CB  1 
ATOM   3807  C CG  . LEU A 1 499 ? 16.165  17.422  82.637  1.00 79.12  ? 574  LEU A CG  1 
ATOM   3808  C CD1 . LEU A 1 499 ? 17.250  16.530  82.058  1.00 80.71  ? 574  LEU A CD1 1 
ATOM   3809  C CD2 . LEU A 1 499 ? 16.551  18.885  82.534  1.00 91.12  ? 574  LEU A CD2 1 
ATOM   3810  N N   . LEU A 1 500 ? 11.811  16.629  81.284  1.00 83.40  ? 575  LEU A N   1 
ATOM   3811  C CA  . LEU A 1 500 ? 10.689  16.670  80.356  1.00 82.05  ? 575  LEU A CA  1 
ATOM   3812  C C   . LEU A 1 500 ? 9.495   17.384  80.973  1.00 83.51  ? 575  LEU A C   1 
ATOM   3813  O O   . LEU A 1 500 ? 8.801   18.150  80.294  1.00 79.35  ? 575  LEU A O   1 
ATOM   3814  C CB  . LEU A 1 500 ? 10.312  15.249  79.939  1.00 60.94  ? 575  LEU A CB  1 
ATOM   3815  C CG  . LEU A 1 500 ? 11.063  14.640  78.755  1.00 64.96  ? 575  LEU A CG  1 
ATOM   3816  C CD1 . LEU A 1 500 ? 10.610  13.209  78.512  1.00 64.89  ? 575  LEU A CD1 1 
ATOM   3817  C CD2 . LEU A 1 500 ? 10.863  15.486  77.509  1.00 77.69  ? 575  LEU A CD2 1 
ATOM   3818  N N   . ALA A 1 501 ? 9.243   17.151  82.264  1.00 74.23  ? 576  ALA A N   1 
ATOM   3819  C CA  . ALA A 1 501 ? 8.128   17.820  82.925  1.00 69.70  ? 576  ALA A CA  1 
ATOM   3820  C C   . ALA A 1 501 ? 8.363   19.323  83.026  1.00 77.56  ? 576  ALA A C   1 
ATOM   3821  O O   . ALA A 1 501 ? 7.447   20.119  82.789  1.00 82.69  ? 576  ALA A O   1 
ATOM   3822  C CB  . ALA A 1 501 ? 7.901   17.218  84.310  1.00 70.41  ? 576  ALA A CB  1 
ATOM   3823  N N   . LYS A 1 502 ? 9.588   19.729  83.372  1.00 75.10  ? 577  LYS A N   1 
ATOM   3824  C CA  . LYS A 1 502 ? 9.886   21.151  83.526  1.00 71.88  ? 577  LYS A CA  1 
ATOM   3825  C C   . LYS A 1 502 ? 9.706   21.913  82.220  1.00 78.92  ? 577  LYS A C   1 
ATOM   3826  O O   . LYS A 1 502 ? 9.361   23.101  82.235  1.00 84.94  ? 577  LYS A O   1 
ATOM   3827  C CB  . LYS A 1 502 ? 11.316  21.347  84.037  1.00 75.72  ? 577  LYS A CB  1 
ATOM   3828  C CG  . LYS A 1 502 ? 11.667  20.634  85.339  1.00 94.32  ? 577  LYS A CG  1 
ATOM   3829  C CD  . LYS A 1 502 ? 10.524  20.634  86.340  1.00 106.58 ? 577  LYS A CD  1 
ATOM   3830  C CE  . LYS A 1 502 ? 10.586  19.411  87.243  1.00 110.16 ? 577  LYS A CE  1 
ATOM   3831  N NZ  . LYS A 1 502 ? 11.831  19.401  88.066  1.00 102.08 ? 577  LYS A NZ  1 
ATOM   3832  N N   . TYR A 1 503 ? 9.934   21.256  81.086  1.00 81.10  ? 578  TYR A N   1 
ATOM   3833  C CA  . TYR A 1 503 ? 9.972   21.919  79.790  1.00 90.20  ? 578  TYR A CA  1 
ATOM   3834  C C   . TYR A 1 503 ? 8.931   21.349  78.833  1.00 78.37  ? 578  TYR A C   1 
ATOM   3835  O O   . TYR A 1 503 ? 9.116   21.389  77.615  1.00 83.66  ? 578  TYR A O   1 
ATOM   3836  C CB  . TYR A 1 503 ? 11.373  21.812  79.189  1.00 91.40  ? 578  TYR A CB  1 
ATOM   3837  C CG  . TYR A 1 503 ? 12.465  22.322  80.103  1.00 83.26  ? 578  TYR A CG  1 
ATOM   3838  C CD1 . TYR A 1 503 ? 12.454  23.631  80.566  1.00 90.80  ? 578  TYR A CD1 1 
ATOM   3839  C CD2 . TYR A 1 503 ? 13.509  21.495  80.501  1.00 86.29  ? 578  TYR A CD2 1 
ATOM   3840  C CE1 . TYR A 1 503 ? 13.447  24.103  81.401  1.00 83.02  ? 578  TYR A CE1 1 
ATOM   3841  C CE2 . TYR A 1 503 ? 14.507  21.959  81.338  1.00 87.93  ? 578  TYR A CE2 1 
ATOM   3842  C CZ  . TYR A 1 503 ? 14.470  23.265  81.784  1.00 84.69  ? 578  TYR A CZ  1 
ATOM   3843  O OH  . TYR A 1 503 ? 15.458  23.738  82.616  1.00 88.39  ? 578  TYR A OH  1 
ATOM   3844  N N   . SER A 1 504 ? 7.827   20.827  79.376  1.00 72.91  ? 579  SER A N   1 
ATOM   3845  C CA  . SER A 1 504 ? 6.837   20.137  78.552  1.00 65.07  ? 579  SER A CA  1 
ATOM   3846  C C   . SER A 1 504 ? 6.255   21.042  77.476  1.00 69.52  ? 579  SER A C   1 
ATOM   3847  O O   . SER A 1 504 ? 5.930   20.572  76.380  1.00 77.27  ? 579  SER A O   1 
ATOM   3848  C CB  . SER A 1 504 ? 5.715   19.585  79.431  1.00 74.43  ? 579  SER A CB  1 
ATOM   3849  O OG  . SER A 1 504 ? 6.105   18.379  80.064  1.00 91.74  ? 579  SER A OG  1 
ATOM   3850  N N   . VAL A 1 505 ? 6.117   22.337  77.762  1.00 70.12  ? 580  VAL A N   1 
ATOM   3851  C CA  . VAL A 1 505 ? 5.489   23.234  76.798  1.00 79.70  ? 580  VAL A CA  1 
ATOM   3852  C C   . VAL A 1 505 ? 6.428   23.540  75.638  1.00 86.96  ? 580  VAL A C   1 
ATOM   3853  O O   . VAL A 1 505 ? 5.983   23.678  74.491  1.00 85.26  ? 580  VAL A O   1 
ATOM   3854  C CB  . VAL A 1 505 ? 5.012   24.517  77.504  1.00 73.39  ? 580  VAL A CB  1 
ATOM   3855  C CG1 . VAL A 1 505 ? 6.147   25.152  78.304  1.00 86.79  ? 580  VAL A CG1 1 
ATOM   3856  C CG2 . VAL A 1 505 ? 4.440   25.504  76.496  1.00 89.42  ? 580  VAL A CG2 1 
ATOM   3857  N N   . ASP A 1 506 ? 7.728   23.632  75.898  1.00 84.48  ? 581  ASP A N   1 
ATOM   3858  C CA  . ASP A 1 506 ? 8.682   24.005  74.863  1.00 84.58  ? 581  ASP A CA  1 
ATOM   3859  C C   . ASP A 1 506 ? 8.966   22.807  73.962  1.00 82.56  ? 581  ASP A C   1 
ATOM   3860  O O   . ASP A 1 506 ? 9.325   21.730  74.447  1.00 82.95  ? 581  ASP A O   1 
ATOM   3861  C CB  . ASP A 1 506 ? 9.971   24.517  75.505  1.00 86.71  ? 581  ASP A CB  1 
ATOM   3862  C CG  . ASP A 1 506 ? 10.903  25.168  74.506  1.00 113.75 ? 581  ASP A CG  1 
ATOM   3863  O OD1 . ASP A 1 506 ? 11.323  24.495  73.541  1.00 137.22 ? 581  ASP A OD1 1 
ATOM   3864  O OD2 . ASP A 1 506 ? 11.230  26.358  74.698  1.00 113.09 ? 581  ASP A OD2 1 
ATOM   3865  N N   . ALA A 1 507 ? 8.826   23.004  72.647  1.00 81.00  ? 582  ALA A N   1 
ATOM   3866  C CA  . ALA A 1 507 ? 8.904   21.890  71.705  1.00 78.26  ? 582  ALA A CA  1 
ATOM   3867  C C   . ALA A 1 507 ? 10.346  21.472  71.431  1.00 90.63  ? 582  ALA A C   1 
ATOM   3868  O O   . ALA A 1 507 ? 10.662  20.275  71.402  1.00 93.74  ? 582  ALA A O   1 
ATOM   3869  C CB  . ALA A 1 507 ? 8.200   22.258  70.397  1.00 74.21  ? 582  ALA A CB  1 
ATOM   3870  N N   . GLU A 1 508 ? 11.230  22.443  71.197  1.00 86.97  ? 583  GLU A N   1 
ATOM   3871  C CA  . GLU A 1 508 ? 12.631  22.123  70.948  1.00 95.25  ? 583  GLU A CA  1 
ATOM   3872  C C   . GLU A 1 508 ? 13.245  21.388  72.135  1.00 86.52  ? 583  GLU A C   1 
ATOM   3873  O O   . GLU A 1 508 ? 13.964  20.390  71.962  1.00 98.69  ? 583  GLU A O   1 
ATOM   3874  C CB  . GLU A 1 508 ? 13.395  23.410  70.631  1.00 92.18  ? 583  GLU A CB  1 
ATOM   3875  C CG  . GLU A 1 508 ? 14.906  23.285  70.621  1.00 122.44 ? 583  GLU A CG  1 
ATOM   3876  C CD  . GLU A 1 508 ? 15.536  23.730  71.928  1.00 134.51 ? 583  GLU A CD  1 
ATOM   3877  O OE1 . GLU A 1 508 ? 14.791  24.139  72.845  1.00 162.02 ? 583  GLU A OE1 1 
ATOM   3878  O OE2 . GLU A 1 508 ? 16.780  23.675  72.035  1.00 135.07 ? 583  GLU A OE2 1 
ATOM   3879  N N   . LYS A 1 509 ? 12.957  21.860  73.350  1.00 77.20  ? 584  LYS A N   1 
ATOM   3880  C CA  . LYS A 1 509 ? 13.475  21.207  74.545  1.00 78.01  ? 584  LYS A CA  1 
ATOM   3881  C C   . LYS A 1 509 ? 13.018  19.756  74.619  1.00 81.40  ? 584  LYS A C   1 
ATOM   3882  O O   . LYS A 1 509 ? 13.824  18.858  74.887  1.00 88.15  ? 584  LYS A O   1 
ATOM   3883  C CB  . LYS A 1 509 ? 13.040  21.969  75.798  1.00 82.75  ? 584  LYS A CB  1 
ATOM   3884  C CG  . LYS A 1 509 ? 13.417  23.441  75.828  1.00 90.26  ? 584  LYS A CG  1 
ATOM   3885  C CD  . LYS A 1 509 ? 13.445  23.953  77.261  1.00 92.57  ? 584  LYS A CD  1 
ATOM   3886  C CE  . LYS A 1 509 ? 14.223  25.246  77.400  1.00 97.08  ? 584  LYS A CE  1 
ATOM   3887  N NZ  . LYS A 1 509 ? 14.090  26.093  76.187  1.00 102.89 ? 584  LYS A NZ  1 
ATOM   3888  N N   . VAL A 1 510 ? 11.728  19.502  74.381  1.00 77.84  ? 585  VAL A N   1 
ATOM   3889  C CA  . VAL A 1 510 ? 11.228  18.142  74.554  1.00 85.11  ? 585  VAL A CA  1 
ATOM   3890  C C   . VAL A 1 510 ? 11.758  17.231  73.455  1.00 80.65  ? 585  VAL A C   1 
ATOM   3891  O O   . VAL A 1 510 ? 12.033  16.057  73.703  1.00 78.53  ? 585  VAL A O   1 
ATOM   3892  C CB  . VAL A 1 510 ? 9.688   18.102  74.631  1.00 73.53  ? 585  VAL A CB  1 
ATOM   3893  C CG1 . VAL A 1 510 ? 9.200   18.752  75.909  1.00 69.97  ? 585  VAL A CG1 1 
ATOM   3894  C CG2 . VAL A 1 510 ? 9.042   18.725  73.414  1.00 77.84  ? 585  VAL A CG2 1 
ATOM   3895  N N   . THR A 1 511 ? 11.938  17.749  72.236  1.00 66.89  ? 586  THR A N   1 
ATOM   3896  C CA  . THR A 1 511 ? 12.555  16.929  71.194  1.00 75.46  ? 586  THR A CA  1 
ATOM   3897  C C   . THR A 1 511 ? 13.969  16.513  71.592  1.00 87.89  ? 586  THR A C   1 
ATOM   3898  O O   . THR A 1 511 ? 14.311  15.317  71.589  1.00 83.67  ? 586  THR A O   1 
ATOM   3899  C CB  . THR A 1 511 ? 12.571  17.676  69.859  1.00 76.12  ? 586  THR A CB  1 
ATOM   3900  O OG1 . THR A 1 511 ? 13.262  18.922  70.008  1.00 99.85  ? 586  THR A OG1 1 
ATOM   3901  C CG2 . THR A 1 511 ? 11.162  17.938  69.369  1.00 68.18  ? 586  THR A CG2 1 
ATOM   3902  N N   . ASN A 1 512 ? 14.806  17.494  71.946  1.00 94.94  ? 587  ASN A N   1 
ATOM   3903  C CA  . ASN A 1 512 ? 16.183  17.178  72.315  1.00 79.16  ? 587  ASN A CA  1 
ATOM   3904  C C   . ASN A 1 512 ? 16.231  16.228  73.508  1.00 72.65  ? 587  ASN A C   1 
ATOM   3905  O O   . ASN A 1 512 ? 17.014  15.270  73.514  1.00 80.14  ? 587  ASN A O   1 
ATOM   3906  C CB  . ASN A 1 512 ? 16.959  18.465  72.600  1.00 77.01  ? 587  ASN A CB  1 
ATOM   3907  C CG  . ASN A 1 512 ? 17.254  19.263  71.337  1.00 91.91  ? 587  ASN A CG  1 
ATOM   3908  O OD1 . ASN A 1 512 ? 17.412  18.701  70.254  1.00 90.42  ? 587  ASN A OD1 1 
ATOM   3909  N ND2 . ASN A 1 512 ? 17.322  20.583  71.473  1.00 87.56  ? 587  ASN A ND2 1 
ATOM   3910  N N   . LEU A 1 513 ? 15.378  16.452  74.510  1.00 68.91  ? 588  LEU A N   1 
ATOM   3911  C CA  . LEU A 1 513 ? 15.384  15.594  75.689  1.00 72.10  ? 588  LEU A CA  1 
ATOM   3912  C C   . LEU A 1 513 ? 14.892  14.191  75.354  1.00 77.92  ? 588  LEU A C   1 
ATOM   3913  O O   . LEU A 1 513 ? 15.379  13.203  75.918  1.00 91.68  ? 588  LEU A O   1 
ATOM   3914  C CB  . LEU A 1 513 ? 14.530  16.218  76.792  1.00 77.07  ? 588  LEU A CB  1 
ATOM   3915  C CG  . LEU A 1 513 ? 15.098  17.484  77.440  1.00 76.58  ? 588  LEU A CG  1 
ATOM   3916  C CD1 . LEU A 1 513 ? 14.051  18.149  78.320  1.00 77.55  ? 588  LEU A CD1 1 
ATOM   3917  C CD2 . LEU A 1 513 ? 16.344  17.156  78.243  1.00 76.14  ? 588  LEU A CD2 1 
ATOM   3918  N N   . LEU A 1 514 ? 13.925  14.082  74.439  1.00 71.87  ? 589  LEU A N   1 
ATOM   3919  C CA  . LEU A 1 514 ? 13.406  12.789  74.018  1.00 68.97  ? 589  LEU A CA  1 
ATOM   3920  C C   . LEU A 1 514 ? 14.436  11.989  73.244  1.00 82.58  ? 589  LEU A C   1 
ATOM   3921  O O   . LEU A 1 514 ? 14.317  10.763  73.158  1.00 84.80  ? 589  LEU A O   1 
ATOM   3922  C CB  . LEU A 1 514 ? 12.168  12.982  73.147  1.00 74.30  ? 589  LEU A CB  1 
ATOM   3923  C CG  . LEU A 1 514 ? 10.801  13.155  73.805  1.00 71.38  ? 589  LEU A CG  1 
ATOM   3924  C CD1 . LEU A 1 514 ? 9.890   13.893  72.837  1.00 73.07  ? 589  LEU A CD1 1 
ATOM   3925  C CD2 . LEU A 1 514 ? 10.207  11.820  74.217  1.00 67.64  ? 589  LEU A CD2 1 
ATOM   3926  N N   . GLN A 1 515 ? 15.415  12.659  72.638  1.00 86.14  ? 590  GLN A N   1 
ATOM   3927  C CA  . GLN A 1 515 ? 16.477  11.901  71.981  1.00 86.07  ? 590  GLN A CA  1 
ATOM   3928  C C   . GLN A 1 515 ? 17.413  11.191  72.960  1.00 74.80  ? 590  GLN A C   1 
ATOM   3929  O O   . GLN A 1 515 ? 18.215  10.358  72.520  1.00 72.40  ? 590  GLN A O   1 
ATOM   3930  C CB  . GLN A 1 515 ? 17.286  12.812  71.060  1.00 73.80  ? 590  GLN A CB  1 
ATOM   3931  C CG  . GLN A 1 515 ? 16.519  13.243  69.829  1.00 76.72  ? 590  GLN A CG  1 
ATOM   3932  C CD  . GLN A 1 515 ? 16.803  14.674  69.436  1.00 96.12  ? 590  GLN A CD  1 
ATOM   3933  O OE1 . GLN A 1 515 ? 17.868  15.212  69.732  1.00 122.32 ? 590  GLN A OE1 1 
ATOM   3934  N NE2 . GLN A 1 515 ? 15.846  15.302  68.765  1.00 107.22 ? 590  GLN A NE2 1 
ATOM   3935  N N   . LEU A 1 516 ? 17.324  11.477  74.267  1.00 66.83  ? 591  LEU A N   1 
ATOM   3936  C CA  . LEU A 1 516 ? 18.260  10.875  75.220  1.00 66.95  ? 591  LEU A CA  1 
ATOM   3937  C C   . LEU A 1 516 ? 18.082  9.369   75.392  1.00 73.31  ? 591  LEU A C   1 
ATOM   3938  O O   . LEU A 1 516 ? 19.100  8.654   75.408  1.00 71.94  ? 591  LEU A O   1 
ATOM   3939  C CB  . LEU A 1 516 ? 18.174  11.598  76.571  1.00 56.47  ? 591  LEU A CB  1 
ATOM   3940  C CG  . LEU A 1 516 ? 18.712  13.027  76.693  1.00 65.60  ? 591  LEU A CG  1 
ATOM   3941  C CD1 . LEU A 1 516 ? 18.976  13.373  78.154  1.00 67.25  ? 591  LEU A CD1 1 
ATOM   3942  C CD2 . LEU A 1 516 ? 19.978  13.176  75.877  1.00 78.51  ? 591  LEU A CD2 1 
ATOM   3943  N N   . PRO A 1 517 ? 16.869  8.822   75.565  1.00 73.45  ? 592  PRO A N   1 
ATOM   3944  C CA  . PRO A 1 517 ? 16.763  7.384   75.884  1.00 63.67  ? 592  PRO A CA  1 
ATOM   3945  C C   . PRO A 1 517 ? 17.392  6.461   74.855  1.00 68.81  ? 592  PRO A C   1 
ATOM   3946  O O   . PRO A 1 517 ? 17.796  5.346   75.210  1.00 75.58  ? 592  PRO A O   1 
ATOM   3947  C CB  . PRO A 1 517 ? 15.246  7.158   75.979  1.00 57.41  ? 592  PRO A CB  1 
ATOM   3948  C CG  . PRO A 1 517 ? 14.700  8.470   76.335  1.00 65.76  ? 592  PRO A CG  1 
ATOM   3949  C CD  . PRO A 1 517 ? 15.549  9.473   75.618  1.00 73.05  ? 592  PRO A CD  1 
ATOM   3950  N N   . GLN A 1 518 ? 17.493  6.886   73.594  1.00 68.19  ? 593  GLN A N   1 
ATOM   3951  C CA  . GLN A 1 518 ? 18.119  6.052   72.574  1.00 56.08  ? 593  GLN A CA  1 
ATOM   3952  C C   . GLN A 1 518 ? 19.569  5.720   72.905  1.00 69.95  ? 593  GLN A C   1 
ATOM   3953  O O   . GLN A 1 518 ? 20.105  4.740   72.378  1.00 76.99  ? 593  GLN A O   1 
ATOM   3954  C CB  . GLN A 1 518 ? 18.023  6.746   71.212  1.00 57.88  ? 593  GLN A CB  1 
ATOM   3955  C CG  . GLN A 1 518 ? 19.328  7.324   70.697  1.00 73.72  ? 593  GLN A CG  1 
ATOM   3956  C CD  . GLN A 1 518 ? 19.147  8.083   69.397  1.00 89.53  ? 593  GLN A CD  1 
ATOM   3957  O OE1 . GLN A 1 518 ? 18.628  9.201   69.386  1.00 87.29  ? 593  GLN A OE1 1 
ATOM   3958  N NE2 . GLN A 1 518 ? 19.572  7.479   68.292  1.00 85.00  ? 593  GLN A NE2 1 
ATOM   3959  N N   . TYR A 1 519 ? 20.207  6.505   73.774  1.00 83.20  ? 594  TYR A N   1 
ATOM   3960  C CA  . TYR A 1 519 ? 21.579  6.271   74.198  1.00 76.88  ? 594  TYR A CA  1 
ATOM   3961  C C   . TYR A 1 519 ? 21.659  5.587   75.559  1.00 78.43  ? 594  TYR A C   1 
ATOM   3962  O O   . TYR A 1 519 ? 22.714  5.619   76.201  1.00 84.99  ? 594  TYR A O   1 
ATOM   3963  C CB  . TYR A 1 519 ? 22.352  7.589   74.232  1.00 55.94  ? 594  TYR A CB  1 
ATOM   3964  C CG  . TYR A 1 519 ? 22.211  8.428   72.983  1.00 55.34  ? 594  TYR A CG  1 
ATOM   3965  C CD1 . TYR A 1 519 ? 22.767  8.016   71.777  1.00 63.47  ? 594  TYR A CD1 1 
ATOM   3966  C CD2 . TYR A 1 519 ? 21.531  9.638   73.011  1.00 62.28  ? 594  TYR A CD2 1 
ATOM   3967  C CE1 . TYR A 1 519 ? 22.646  8.785   70.634  1.00 64.77  ? 594  TYR A CE1 1 
ATOM   3968  C CE2 . TYR A 1 519 ? 21.403  10.413  71.875  1.00 70.44  ? 594  TYR A CE2 1 
ATOM   3969  C CZ  . TYR A 1 519 ? 21.963  9.983   70.689  1.00 74.64  ? 594  TYR A CZ  1 
ATOM   3970  O OH  . TYR A 1 519 ? 21.839  10.753  69.555  1.00 79.69  ? 594  TYR A OH  1 
ATOM   3971  N N   . PHE A 1 520 ? 20.571  4.978   76.013  1.00 78.56  ? 595  PHE A N   1 
ATOM   3972  C CA  . PHE A 1 520 ? 20.532  4.312   77.305  1.00 82.63  ? 595  PHE A CA  1 
ATOM   3973  C C   . PHE A 1 520 ? 20.743  2.814   77.123  1.00 90.47  ? 595  PHE A C   1 
ATOM   3974  O O   . PHE A 1 520 ? 20.495  2.252   76.052  1.00 98.69  ? 595  PHE A O   1 
ATOM   3975  C CB  . PHE A 1 520 ? 19.194  4.554   78.014  1.00 78.84  ? 595  PHE A CB  1 
ATOM   3976  C CG  . PHE A 1 520 ? 18.970  5.979   78.454  1.00 74.90  ? 595  PHE A CG  1 
ATOM   3977  C CD1 . PHE A 1 520 ? 19.917  6.963   78.222  1.00 88.97  ? 595  PHE A CD1 1 
ATOM   3978  C CD2 . PHE A 1 520 ? 17.796  6.330   79.100  1.00 67.57  ? 595  PHE A CD2 1 
ATOM   3979  C CE1 . PHE A 1 520 ? 19.695  8.266   78.626  1.00 92.09  ? 595  PHE A CE1 1 
ATOM   3980  C CE2 . PHE A 1 520 ? 17.570  7.629   79.506  1.00 67.79  ? 595  PHE A CE2 1 
ATOM   3981  C CZ  . PHE A 1 520 ? 18.519  8.598   79.267  1.00 69.57  ? 595  PHE A CZ  1 
ATOM   3982  N N   . ASP A 1 521 ? 21.214  2.171   78.188  1.00 84.28  ? 596  ASP A N   1 
ATOM   3983  C CA  . ASP A 1 521 ? 21.233  0.715   78.286  1.00 86.95  ? 596  ASP A CA  1 
ATOM   3984  C C   . ASP A 1 521 ? 19.975  0.322   79.050  1.00 98.78  ? 596  ASP A C   1 
ATOM   3985  O O   . ASP A 1 521 ? 19.931  0.413   80.278  1.00 96.66  ? 596  ASP A O   1 
ATOM   3986  C CB  . ASP A 1 521 ? 22.497  0.217   78.978  1.00 92.26  ? 596  ASP A CB  1 
ATOM   3987  C CG  . ASP A 1 521 ? 23.746  0.464   78.155  1.00 111.94 ? 596  ASP A CG  1 
ATOM   3988  O OD1 . ASP A 1 521 ? 24.851  0.135   78.633  1.00 111.21 ? 596  ASP A OD1 1 
ATOM   3989  O OD2 . ASP A 1 521 ? 23.622  0.989   77.029  1.00 128.09 ? 596  ASP A OD2 1 
ATOM   3990  N N   . LEU A 1 522 ? 18.947  -0.110  78.316  1.00 102.07 ? 597  LEU A N   1 
ATOM   3991  C CA  . LEU A 1 522 ? 17.649  -0.368  78.931  1.00 97.28  ? 597  LEU A CA  1 
ATOM   3992  C C   . LEU A 1 522 ? 17.701  -1.496  79.952  1.00 97.25  ? 597  LEU A C   1 
ATOM   3993  O O   . LEU A 1 522 ? 16.809  -1.586  80.803  1.00 100.71 ? 597  LEU A O   1 
ATOM   3994  C CB  . LEU A 1 522 ? 16.619  -0.689  77.850  1.00 96.42  ? 597  LEU A CB  1 
ATOM   3995  C CG  . LEU A 1 522 ? 16.445  0.361   76.752  1.00 90.44  ? 597  LEU A CG  1 
ATOM   3996  C CD1 . LEU A 1 522 ? 15.242  0.024   75.882  1.00 98.68  ? 597  LEU A CD1 1 
ATOM   3997  C CD2 . LEU A 1 522 ? 16.321  1.760   77.341  1.00 74.31  ? 597  LEU A CD2 1 
ATOM   3998  N N   . GLU A 1 523 ? 18.718  -2.359  79.885  1.00 95.95  ? 598  GLU A N   1 
ATOM   3999  C CA  . GLU A 1 523 ? 18.897  -3.372  80.919  1.00 94.39  ? 598  GLU A CA  1 
ATOM   4000  C C   . GLU A 1 523 ? 19.154  -2.739  82.279  1.00 77.30  ? 598  GLU A C   1 
ATOM   4001  O O   . GLU A 1 523 ? 18.854  -3.346  83.313  1.00 85.77  ? 598  GLU A O   1 
ATOM   4002  C CB  . GLU A 1 523 ? 20.049  -4.308  80.547  1.00 114.36 ? 598  GLU A CB  1 
ATOM   4003  C CG  . GLU A 1 523 ? 19.987  -5.677  81.209  1.00 116.61 ? 598  GLU A CG  1 
ATOM   4004  C CD  . GLU A 1 523 ? 21.363  -6.196  81.593  1.00 138.39 ? 598  GLU A CD  1 
ATOM   4005  O OE1 . GLU A 1 523 ? 22.364  -5.699  81.034  1.00 129.93 ? 598  GLU A OE1 1 
ATOM   4006  O OE2 . GLU A 1 523 ? 21.445  -7.094  82.458  1.00 140.39 ? 598  GLU A OE2 1 
ATOM   4007  N N   . ILE A 1 524 ? 19.708  -1.524  82.296  1.00 77.08  ? 599  ILE A N   1 
ATOM   4008  C CA  . ILE A 1 524 ? 19.979  -0.837  83.556  1.00 82.72  ? 599  ILE A CA  1 
ATOM   4009  C C   . ILE A 1 524 ? 18.679  -0.542  84.292  1.00 84.63  ? 599  ILE A C   1 
ATOM   4010  O O   . ILE A 1 524 ? 18.624  -0.585  85.527  1.00 82.70  ? 599  ILE A O   1 
ATOM   4011  C CB  . ILE A 1 524 ? 20.784  0.450   83.294  1.00 79.57  ? 599  ILE A CB  1 
ATOM   4012  C CG1 . ILE A 1 524 ? 22.149  0.112   82.689  1.00 64.40  ? 599  ILE A CG1 1 
ATOM   4013  C CG2 . ILE A 1 524 ? 20.937  1.261   84.574  1.00 65.20  ? 599  ILE A CG2 1 
ATOM   4014  C CD1 . ILE A 1 524 ? 23.223  1.124   82.994  1.00 73.57  ? 599  ILE A CD1 1 
ATOM   4015  N N   . TYR A 1 525 ? 17.612  -0.240  83.545  1.00 92.26  ? 600  TYR A N   1 
ATOM   4016  C CA  . TYR A 1 525 ? 16.313  0.023   84.161  1.00 87.09  ? 600  TYR A CA  1 
ATOM   4017  C C   . TYR A 1 525 ? 15.871  -1.144  85.036  1.00 85.47  ? 600  TYR A C   1 
ATOM   4018  O O   . TYR A 1 525 ? 15.403  -0.950  86.164  1.00 81.52  ? 600  TYR A O   1 
ATOM   4019  C CB  . TYR A 1 525 ? 15.267  0.313   83.082  1.00 69.75  ? 600  TYR A CB  1 
ATOM   4020  C CG  . TYR A 1 525 ? 15.009  1.785   82.835  1.00 78.22  ? 600  TYR A CG  1 
ATOM   4021  C CD1 . TYR A 1 525 ? 14.663  2.635   83.878  1.00 81.72  ? 600  TYR A CD1 1 
ATOM   4022  C CD2 . TYR A 1 525 ? 15.099  2.322   81.556  1.00 74.31  ? 600  TYR A CD2 1 
ATOM   4023  C CE1 . TYR A 1 525 ? 14.422  3.981   83.656  1.00 86.46  ? 600  TYR A CE1 1 
ATOM   4024  C CE2 . TYR A 1 525 ? 14.859  3.665   81.324  1.00 55.14  ? 600  TYR A CE2 1 
ATOM   4025  C CZ  . TYR A 1 525 ? 14.522  4.489   82.376  1.00 76.75  ? 600  TYR A CZ  1 
ATOM   4026  O OH  . TYR A 1 525 ? 14.283  5.825   82.145  1.00 77.72  ? 600  TYR A OH  1 
ATOM   4027  N N   . THR A 1 526 ? 16.024  -2.369  84.530  1.00 79.87  ? 601  THR A N   1 
ATOM   4028  C CA  . THR A 1 526 ? 15.631  -3.550  85.293  1.00 88.01  ? 601  THR A CA  1 
ATOM   4029  C C   . THR A 1 526 ? 16.648  -3.879  86.379  1.00 87.91  ? 601  THR A C   1 
ATOM   4030  O O   . THR A 1 526 ? 16.280  -4.096  87.538  1.00 98.37  ? 601  THR A O   1 
ATOM   4031  C CB  . THR A 1 526 ? 15.456  -4.751  84.362  1.00 88.09  ? 601  THR A CB  1 
ATOM   4032  O OG1 . THR A 1 526 ? 16.708  -5.432  84.220  1.00 104.74 ? 601  THR A OG1 1 
ATOM   4033  C CG2 . THR A 1 526 ? 14.990  -4.299  82.998  1.00 82.37  ? 601  THR A CG2 1 
ATOM   4034  N N   . THR A 1 527 ? 17.934  -3.922  86.020  1.00 85.98  ? 602  THR A N   1 
ATOM   4035  C CA  . THR A 1 527 ? 18.958  -4.292  86.993  1.00 80.66  ? 602  THR A CA  1 
ATOM   4036  C C   . THR A 1 527 ? 19.027  -3.288  88.139  1.00 89.53  ? 602  THR A C   1 
ATOM   4037  O O   . THR A 1 527 ? 19.216  -3.671  89.300  1.00 97.46  ? 602  THR A O   1 
ATOM   4038  C CB  . THR A 1 527 ? 20.319  -4.420  86.304  1.00 85.64  ? 602  THR A CB  1 
ATOM   4039  O OG1 . THR A 1 527 ? 20.710  -3.155  85.752  1.00 79.36  ? 602  THR A OG1 1 
ATOM   4040  C CG2 . THR A 1 527 ? 20.268  -5.462  85.194  1.00 83.69  ? 602  THR A CG2 1 
ATOM   4041  N N   . GLY A 1 528 ? 18.874  -2.003  87.838  1.00 95.53  ? 603  GLY A N   1 
ATOM   4042  C CA  . GLY A 1 528 ? 18.986  -0.975  88.855  1.00 97.39  ? 603  GLY A CA  1 
ATOM   4043  C C   . GLY A 1 528 ? 17.650  -0.623  89.471  1.00 101.45 ? 603  GLY A C   1 
ATOM   4044  O O   . GLY A 1 528 ? 17.515  0.422   90.116  1.00 103.56 ? 603  GLY A O   1 
ATOM   4045  N N   . ARG A 1 529 ? 16.665  -1.500  89.274  1.00 102.14 ? 604  ARG A N   1 
ATOM   4046  C CA  . ARG A 1 529 ? 15.299  -1.352  89.793  1.00 114.73 ? 604  ARG A CA  1 
ATOM   4047  C C   . ARG A 1 529 ? 14.795  0.087   89.669  1.00 117.72 ? 604  ARG A C   1 
ATOM   4048  O O   . ARG A 1 529 ? 14.221  0.664   90.594  1.00 124.47 ? 604  ARG A O   1 
ATOM   4049  C CB  . ARG A 1 529 ? 15.196  -1.876  91.234  1.00 116.99 ? 604  ARG A CB  1 
ATOM   4050  C CG  . ARG A 1 529 ? 16.023  -1.146  92.287  1.00 124.34 ? 604  ARG A CG  1 
ATOM   4051  C CD  . ARG A 1 529 ? 16.454  -2.096  93.398  1.00 148.08 ? 604  ARG A CD  1 
ATOM   4052  N NE  . ARG A 1 529 ? 17.611  -2.906  93.028  1.00 157.55 ? 604  ARG A NE  1 
ATOM   4053  C CZ  . ARG A 1 529 ? 18.848  -2.445  92.885  1.00 154.28 ? 604  ARG A CZ  1 
ATOM   4054  N NH1 . ARG A 1 529 ? 19.134  -1.165  93.054  1.00 158.12 ? 604  ARG A NH1 1 
ATOM   4055  N NH2 . ARG A 1 529 ? 19.822  -3.291  92.562  1.00 161.45 ? 604  ARG A NH2 1 
ATOM   4056  N N   . LEU A 1 530 ? 15.001  0.664   88.484  1.00 108.13 ? 605  LEU A N   1 
ATOM   4057  C CA  . LEU A 1 530 ? 14.572  2.023   88.184  1.00 98.38  ? 605  LEU A CA  1 
ATOM   4058  C C   . LEU A 1 530 ? 13.241  2.062   87.440  1.00 103.64 ? 605  LEU A C   1 
ATOM   4059  O O   . LEU A 1 530 ? 12.942  3.061   86.774  1.00 102.10 ? 605  LEU A O   1 
ATOM   4060  C CB  . LEU A 1 530 ? 15.646  2.744   87.370  1.00 97.05  ? 605  LEU A CB  1 
ATOM   4061  C CG  . LEU A 1 530 ? 17.058  2.761   87.957  1.00 99.44  ? 605  LEU A CG  1 
ATOM   4062  C CD1 . LEU A 1 530 ? 18.085  2.652   86.846  1.00 93.03  ? 605  LEU A CD1 1 
ATOM   4063  C CD2 . LEU A 1 530 ? 17.288  4.019   88.780  1.00 100.54 ? 605  LEU A CD2 1 
ATOM   4064  N N   . GLU A 1 531 ? 12.433  1.002   87.551  1.00 104.37 ? 606  GLU A N   1 
ATOM   4065  C CA  . GLU A 1 531 ? 11.218  0.892   86.745  1.00 91.46  ? 606  GLU A CA  1 
ATOM   4066  C C   . GLU A 1 531 ? 10.264  2.056   86.985  1.00 92.06  ? 606  GLU A C   1 
ATOM   4067  O O   . GLU A 1 531 ? 9.546   2.468   86.066  1.00 96.99  ? 606  GLU A O   1 
ATOM   4068  C CB  . GLU A 1 531 ? 10.513  -0.435  87.038  1.00 99.99  ? 606  GLU A CB  1 
ATOM   4069  C CG  . GLU A 1 531 ? 11.002  -1.616  86.212  1.00 100.91 ? 606  GLU A CG  1 
ATOM   4070  C CD  . GLU A 1 531 ? 12.179  -2.329  86.855  1.00 100.50 ? 606  GLU A CD  1 
ATOM   4071  O OE1 . GLU A 1 531 ? 12.851  -1.713  87.707  1.00 94.69  ? 606  GLU A OE1 1 
ATOM   4072  O OE2 . GLU A 1 531 ? 12.433  -3.503  86.509  1.00 106.30 ? 606  GLU A OE2 1 
ATOM   4073  N N   . LYS A 1 532 ? 10.233  2.591   88.208  1.00 93.27  ? 607  LYS A N   1 
ATOM   4074  C CA  . LYS A 1 532 ? 9.380   3.741   88.494  1.00 100.74 ? 607  LYS A CA  1 
ATOM   4075  C C   . LYS A 1 532 ? 9.764   4.932   87.622  1.00 98.22  ? 607  LYS A C   1 
ATOM   4076  O O   . LYS A 1 532 ? 8.890   5.629   87.087  1.00 102.43 ? 607  LYS A O   1 
ATOM   4077  C CB  . LYS A 1 532 ? 9.455   4.069   89.995  1.00 100.44 ? 607  LYS A CB  1 
ATOM   4078  C CG  . LYS A 1 532 ? 8.746   5.343   90.530  1.00 105.82 ? 607  LYS A CG  1 
ATOM   4079  C CD  . LYS A 1 532 ? 9.386   6.664   90.104  1.00 109.31 ? 607  LYS A CD  1 
ATOM   4080  C CE  . LYS A 1 532 ? 8.662   7.861   90.684  1.00 111.00 ? 607  LYS A CE  1 
ATOM   4081  N NZ  . LYS A 1 532 ? 9.394   9.124   90.398  1.00 109.37 ? 607  LYS A NZ  1 
ATOM   4082  N N   . HIS A 1 533 ? 11.064  5.194   87.482  1.00 94.20  ? 608  HIS A N   1 
ATOM   4083  C CA  . HIS A 1 533 ? 11.502  6.303   86.644  1.00 99.16  ? 608  HIS A CA  1 
ATOM   4084  C C   . HIS A 1 533 ? 11.165  6.063   85.177  1.00 98.81  ? 608  HIS A C   1 
ATOM   4085  O O   . HIS A 1 533 ? 10.834  7.010   84.454  1.00 93.48  ? 608  HIS A O   1 
ATOM   4086  C CB  . HIS A 1 533 ? 13.002  6.522   86.832  1.00 89.43  ? 608  HIS A CB  1 
ATOM   4087  C CG  . HIS A 1 533 ? 13.420  6.609   88.267  1.00 80.52  ? 608  HIS A CG  1 
ATOM   4088  N ND1 . HIS A 1 533 ? 13.117  7.691   89.066  1.00 75.65  ? 608  HIS A ND1 1 
ATOM   4089  C CD2 . HIS A 1 533 ? 14.109  5.746   89.049  1.00 88.63  ? 608  HIS A CD2 1 
ATOM   4090  C CE1 . HIS A 1 533 ? 13.605  7.491   90.277  1.00 88.85  ? 608  HIS A CE1 1 
ATOM   4091  N NE2 . HIS A 1 533 ? 14.212  6.318   90.293  1.00 92.83  ? 608  HIS A NE2 1 
ATOM   4092  N N   . LEU A 1 534 ? 11.232  4.807   84.730  1.00 94.95  ? 609  LEU A N   1 
ATOM   4093  C CA  . LEU A 1 534 ? 10.794  4.478   83.378  1.00 89.16  ? 609  LEU A CA  1 
ATOM   4094  C C   . LEU A 1 534 ? 9.311   4.771   83.195  1.00 88.04  ? 609  LEU A C   1 
ATOM   4095  O O   . LEU A 1 534 ? 8.898   5.294   82.154  1.00 95.82  ? 609  LEU A O   1 
ATOM   4096  C CB  . LEU A 1 534 ? 11.086  3.009   83.074  1.00 90.00  ? 609  LEU A CB  1 
ATOM   4097  C CG  . LEU A 1 534 ? 10.359  2.426   81.861  1.00 79.89  ? 609  LEU A CG  1 
ATOM   4098  C CD1 . LEU A 1 534 ? 10.891  3.023   80.565  1.00 80.56  ? 609  LEU A CD1 1 
ATOM   4099  C CD2 . LEU A 1 534 ? 10.470  0.912   81.848  1.00 76.63  ? 609  LEU A CD2 1 
ATOM   4100  N N   . ASP A 1 535 ? 8.493   4.432   84.196  1.00 88.16  ? 610  ASP A N   1 
ATOM   4101  C CA  . ASP A 1 535 ? 7.063   4.718   84.116  1.00 93.30  ? 610  ASP A CA  1 
ATOM   4102  C C   . ASP A 1 535 ? 6.805   6.219   84.062  1.00 90.94  ? 610  ASP A C   1 
ATOM   4103  O O   . ASP A 1 535 ? 5.949   6.686   83.300  1.00 92.60  ? 610  ASP A O   1 
ATOM   4104  C CB  . ASP A 1 535 ? 6.331   4.097   85.306  1.00 96.75  ? 610  ASP A CB  1 
ATOM   4105  C CG  . ASP A 1 535 ? 6.481   2.590   85.367  1.00 104.65 ? 610  ASP A CG  1 
ATOM   4106  O OD1 . ASP A 1 535 ? 6.708   1.968   84.308  1.00 101.96 ? 610  ASP A OD1 1 
ATOM   4107  O OD2 . ASP A 1 535 ? 6.372   2.029   86.478  1.00 98.63  ? 610  ASP A OD2 1 
ATOM   4108  N N   . ALA A 1 536 ? 7.531   6.988   84.878  1.00 90.79  ? 611  ALA A N   1 
ATOM   4109  C CA  . ALA A 1 536 ? 7.378   8.440   84.852  1.00 95.78  ? 611  ALA A CA  1 
ATOM   4110  C C   . ALA A 1 536 ? 7.770   9.008   83.493  1.00 83.10  ? 611  ALA A C   1 
ATOM   4111  O O   . ALA A 1 536 ? 7.082   9.883   82.951  1.00 76.67  ? 611  ALA A O   1 
ATOM   4112  C CB  . ALA A 1 536 ? 8.208   9.077   85.967  1.00 88.21  ? 611  ALA A CB  1 
ATOM   4113  N N   . LEU A 1 537 ? 8.867   8.506   82.919  1.00 82.65  ? 612  LEU A N   1 
ATOM   4114  C CA  . LEU A 1 537 ? 9.284   8.939   81.589  1.00 89.33  ? 612  LEU A CA  1 
ATOM   4115  C C   . LEU A 1 537 ? 8.226   8.609   80.541  1.00 92.13  ? 612  LEU A C   1 
ATOM   4116  O O   . LEU A 1 537 ? 7.917   9.439   79.676  1.00 91.97  ? 612  LEU A O   1 
ATOM   4117  C CB  . LEU A 1 537 ? 10.621  8.287   81.232  1.00 87.97  ? 612  LEU A CB  1 
ATOM   4118  C CG  . LEU A 1 537 ? 11.014  8.254   79.754  1.00 83.58  ? 612  LEU A CG  1 
ATOM   4119  C CD1 . LEU A 1 537 ? 11.427  9.636   79.272  1.00 78.89  ? 612  LEU A CD1 1 
ATOM   4120  C CD2 . LEU A 1 537 ? 12.125  7.239   79.518  1.00 80.12  ? 612  LEU A CD2 1 
ATOM   4121  N N   . LEU A 1 538 ? 7.666   7.397   80.600  1.00 84.74  ? 613  LEU A N   1 
ATOM   4122  C CA  . LEU A 1 538 ? 6.634   6.993   79.648  1.00 78.99  ? 613  LEU A CA  1 
ATOM   4123  C C   . LEU A 1 538 ? 5.417   7.903   79.747  1.00 86.91  ? 613  LEU A C   1 
ATOM   4124  O O   . LEU A 1 538 ? 4.862   8.342   78.728  1.00 96.01  ? 613  LEU A O   1 
ATOM   4125  C CB  . LEU A 1 538 ? 6.234   5.539   79.904  1.00 64.00  ? 613  LEU A CB  1 
ATOM   4126  C CG  . LEU A 1 538 ? 7.236   4.441   79.551  1.00 68.77  ? 613  LEU A CG  1 
ATOM   4127  C CD1 . LEU A 1 538 ? 6.708   3.085   79.989  1.00 74.73  ? 613  LEU A CD1 1 
ATOM   4128  C CD2 . LEU A 1 538 ? 7.539   4.444   78.064  1.00 80.68  ? 613  LEU A CD2 1 
ATOM   4129  N N   . ARG A 1 539 ? 4.980   8.184   80.978  1.00 84.57  ? 614  ARG A N   1 
ATOM   4130  C CA  . ARG A 1 539 ? 3.842   9.075   81.173  1.00 89.83  ? 614  ARG A CA  1 
ATOM   4131  C C   . ARG A 1 539 ? 4.140   10.472  80.646  1.00 83.40  ? 614  ARG A C   1 
ATOM   4132  O O   . ARG A 1 539 ? 3.264   11.123  80.066  1.00 85.45  ? 614  ARG A O   1 
ATOM   4133  C CB  . ARG A 1 539 ? 3.455   9.130   82.652  1.00 96.66  ? 614  ARG A CB  1 
ATOM   4134  C CG  . ARG A 1 539 ? 2.775   7.869   83.167  1.00 115.82 ? 614  ARG A CG  1 
ATOM   4135  C CD  . ARG A 1 539 ? 2.641   7.871   84.686  1.00 139.94 ? 614  ARG A CD  1 
ATOM   4136  N NE  . ARG A 1 539 ? 3.720   7.152   85.354  1.00 165.16 ? 614  ARG A NE  1 
ATOM   4137  C CZ  . ARG A 1 539 ? 4.340   7.577   86.447  1.00 165.63 ? 614  ARG A CZ  1 
ATOM   4138  N NH1 . ARG A 1 539 ? 4.021   8.725   87.022  1.00 159.04 ? 614  ARG A NH1 1 
ATOM   4139  N NH2 . ARG A 1 539 ? 5.298   6.826   86.983  1.00 164.13 ? 614  ARG A NH2 1 
ATOM   4140  N N   . GLN A 1 540 ? 5.374   10.948  80.827  1.00 78.95  ? 615  GLN A N   1 
ATOM   4141  C CA  . GLN A 1 540 ? 5.716   12.276  80.326  1.00 78.76  ? 615  GLN A CA  1 
ATOM   4142  C C   . GLN A 1 540 ? 5.688   12.309  78.799  1.00 87.48  ? 615  GLN A C   1 
ATOM   4143  O O   . GLN A 1 540 ? 5.211   13.282  78.196  1.00 88.58  ? 615  GLN A O   1 
ATOM   4144  C CB  . GLN A 1 540 ? 7.088   12.692  80.856  1.00 74.30  ? 615  GLN A CB  1 
ATOM   4145  C CG  . GLN A 1 540 ? 7.193   14.165  81.212  1.00 87.75  ? 615  GLN A CG  1 
ATOM   4146  C CD  . GLN A 1 540 ? 6.308   14.539  82.385  1.00 91.45  ? 615  GLN A CD  1 
ATOM   4147  O OE1 . GLN A 1 540 ? 6.467   14.012  83.487  1.00 81.81  ? 615  GLN A OE1 1 
ATOM   4148  N NE2 . GLN A 1 540 ? 5.371   15.455  82.157  1.00 89.09  ? 615  GLN A NE2 1 
ATOM   4149  N N   . ILE A 1 541 ? 6.184   11.245  78.161  1.00 86.24  ? 616  ILE A N   1 
ATOM   4150  C CA  . ILE A 1 541 ? 6.145   11.164  76.702  1.00 78.02  ? 616  ILE A CA  1 
ATOM   4151  C C   . ILE A 1 541 ? 4.704   11.192  76.207  1.00 86.15  ? 616  ILE A C   1 
ATOM   4152  O O   . ILE A 1 541 ? 4.365   11.924  75.268  1.00 77.78  ? 616  ILE A O   1 
ATOM   4153  C CB  . ILE A 1 541 ? 6.886   9.908   76.207  1.00 80.58  ? 616  ILE A CB  1 
ATOM   4154  C CG1 . ILE A 1 541 ? 8.344   9.923   76.666  1.00 85.04  ? 616  ILE A CG1 1 
ATOM   4155  C CG2 . ILE A 1 541 ? 6.807   9.800   74.693  1.00 79.80  ? 616  ILE A CG2 1 
ATOM   4156  C CD1 . ILE A 1 541 ? 9.019   8.574   76.604  1.00 82.30  ? 616  ILE A CD1 1 
ATOM   4157  N N   . ARG A 1 542 ? 3.834   10.392  76.830  1.00 87.74  ? 617  ARG A N   1 
ATOM   4158  C CA  . ARG A 1 542 ? 2.435   10.361  76.408  1.00 82.59  ? 617  ARG A CA  1 
ATOM   4159  C C   . ARG A 1 542 ? 1.757   11.712  76.638  1.00 86.33  ? 617  ARG A C   1 
ATOM   4160  O O   . ARG A 1 542 ? 0.969   12.173  75.798  1.00 95.19  ? 617  ARG A O   1 
ATOM   4161  C CB  . ARG A 1 542 ? 1.723   9.213   77.137  1.00 75.05  ? 617  ARG A CB  1 
ATOM   4162  C CG  . ARG A 1 542 ? 1.006   9.587   78.422  1.00 110.22 ? 617  ARG A CG  1 
ATOM   4163  C CD  . ARG A 1 542 ? 0.369   8.381   79.117  1.00 118.92 ? 617  ARG A CD  1 
ATOM   4164  N NE  . ARG A 1 542 ? -0.443  7.518   78.267  1.00 108.27 ? 617  ARG A NE  1 
ATOM   4165  C CZ  . ARG A 1 542 ? -1.616  7.849   77.743  1.00 125.10 ? 617  ARG A CZ  1 
ATOM   4166  N NH1 . ARG A 1 542 ? -2.139  9.052   77.919  1.00 131.30 ? 617  ARG A NH1 1 
ATOM   4167  N NH2 . ARG A 1 542 ? -2.289  6.944   77.041  1.00 115.73 ? 617  ARG A NH2 1 
ATOM   4168  N N   . ASN A 1 543 ? 2.102   12.392  77.735  1.00 81.60  ? 618  ASN A N   1 
ATOM   4169  C CA  . ASN A 1 543 ? 1.536   13.709  77.997  1.00 84.79  ? 618  ASN A CA  1 
ATOM   4170  C C   . ASN A 1 543 ? 1.932   14.700  76.916  1.00 86.50  ? 618  ASN A C   1 
ATOM   4171  O O   . ASN A 1 543 ? 1.099   15.489  76.449  1.00 102.30 ? 618  ASN A O   1 
ATOM   4172  C CB  . ASN A 1 543 ? 1.992   14.208  79.366  1.00 68.60  ? 618  ASN A CB  1 
ATOM   4173  C CG  . ASN A 1 543 ? 1.410   13.398  80.509  1.00 92.52  ? 618  ASN A CG  1 
ATOM   4174  O OD1 . ASN A 1 543 ? 0.380   12.737  80.359  1.00 112.46 ? 618  ASN A OD1 1 
ATOM   4175  N ND2 . ASN A 1 543 ? 2.080   13.430  81.653  1.00 102.52 ? 618  ASN A ND2 1 
ATOM   4176  N N   . ILE A 1 544 ? 3.200   14.672  76.495  1.00 82.73  ? 619  ILE A N   1 
ATOM   4177  C CA  . ILE A 1 544 ? 3.619   15.646  75.493  1.00 95.90  ? 619  ILE A CA  1 
ATOM   4178  C C   . ILE A 1 544 ? 3.091   15.274  74.112  1.00 90.99  ? 619  ILE A C   1 
ATOM   4179  O O   . ILE A 1 544 ? 2.908   16.155  73.266  1.00 88.66  ? 619  ILE A O   1 
ATOM   4180  C CB  . ILE A 1 544 ? 5.151   15.833  75.488  1.00 92.78  ? 619  ILE A CB  1 
ATOM   4181  C CG1 . ILE A 1 544 ? 5.870   14.580  74.988  1.00 88.26  ? 619  ILE A CG1 1 
ATOM   4182  C CG2 . ILE A 1 544 ? 5.645   16.237  76.870  1.00 83.08  ? 619  ILE A CG2 1 
ATOM   4183  C CD1 . ILE A 1 544 ? 7.374   14.680  75.070  1.00 98.47  ? 619  ILE A CD1 1 
ATOM   4184  N N   . VAL A 1 545 ? 2.824   13.988  73.847  1.00 86.26  ? 620  VAL A N   1 
ATOM   4185  C CA  . VAL A 1 545 ? 2.183   13.691  72.566  1.00 77.08  ? 620  VAL A CA  1 
ATOM   4186  C C   . VAL A 1 545 ? 0.766   14.233  72.576  1.00 75.66  ? 620  VAL A C   1 
ATOM   4187  O O   . VAL A 1 545 ? 0.260   14.692  71.544  1.00 80.99  ? 620  VAL A O   1 
ATOM   4188  C CB  . VAL A 1 545 ? 2.178   12.188  72.199  1.00 63.51  ? 620  VAL A CB  1 
ATOM   4189  C CG1 . VAL A 1 545 ? 3.559   11.597  72.236  1.00 85.07  ? 620  VAL A CG1 1 
ATOM   4190  C CG2 . VAL A 1 545 ? 1.185   11.377  73.017  1.00 72.29  ? 620  VAL A CG2 1 
ATOM   4191  N N   . GLU A 1 546 ? 0.101   14.201  73.733  1.00 86.34  ? 621  GLU A N   1 
ATOM   4192  C CA  . GLU A 1 546 ? -1.252  14.743  73.786  1.00 87.18  ? 621  GLU A CA  1 
ATOM   4193  C C   . GLU A 1 546 ? -1.244  16.263  73.673  1.00 86.35  ? 621  GLU A C   1 
ATOM   4194  O O   . GLU A 1 546 ? -2.124  16.847  73.032  1.00 98.03  ? 621  GLU A O   1 
ATOM   4195  C CB  . GLU A 1 546 ? -1.955  14.287  75.062  1.00 78.23  ? 621  GLU A CB  1 
ATOM   4196  C CG  . GLU A 1 546 ? -2.241  12.796  75.074  1.00 87.64  ? 621  GLU A CG  1 
ATOM   4197  C CD  . GLU A 1 546 ? -2.093  12.190  76.444  1.00 108.12 ? 621  GLU A CD  1 
ATOM   4198  O OE1 . GLU A 1 546 ? -1.803  12.948  77.392  1.00 104.92 ? 621  GLU A OE1 1 
ATOM   4199  O OE2 . GLU A 1 546 ? -2.273  10.961  76.575  1.00 114.03 ? 621  GLU A OE2 1 
ATOM   4200  N N   . LYS A 1 547 ? -0.242  16.918  74.259  1.00 86.30  ? 622  LYS A N   1 
ATOM   4201  C CA  . LYS A 1 547 ? -0.214  18.377  74.270  1.00 80.47  ? 622  LYS A CA  1 
ATOM   4202  C C   . LYS A 1 547 ? 0.243   18.922  72.920  1.00 76.07  ? 622  LYS A C   1 
ATOM   4203  O O   . LYS A 1 547 ? -0.314  19.915  72.435  1.00 71.27  ? 622  LYS A O   1 
ATOM   4204  C CB  . LYS A 1 547 ? 0.703   18.846  75.418  1.00 82.83  ? 622  LYS A CB  1 
ATOM   4205  C CG  . LYS A 1 547 ? 1.274   20.298  75.495  1.00 107.20 ? 622  LYS A CG  1 
ATOM   4206  C CD  . LYS A 1 547 ? 0.475   21.409  74.840  1.00 118.63 ? 622  LYS A CD  1 
ATOM   4207  C CE  . LYS A 1 547 ? 1.059   22.771  75.189  1.00 127.40 ? 622  LYS A CE  1 
ATOM   4208  N NZ  . LYS A 1 547 ? 2.370   23.034  74.522  1.00 133.64 ? 622  LYS A NZ  1 
ATOM   4209  N N   . HIS A 1 548 ? 1.209   18.268  72.281  1.00 89.71  ? 623  HIS A N   1 
ATOM   4210  C CA  . HIS A 1 548 ? 1.945   18.856  71.172  1.00 85.26  ? 623  HIS A CA  1 
ATOM   4211  C C   . HIS A 1 548 ? 1.361   18.455  69.826  1.00 78.55  ? 623  HIS A C   1 
ATOM   4212  O O   . HIS A 1 548 ? 0.907   17.320  69.643  1.00 78.88  ? 623  HIS A O   1 
ATOM   4213  C CB  . HIS A 1 548 ? 3.418   18.448  71.225  1.00 79.82  ? 623  HIS A CB  1 
ATOM   4214  C CG  . HIS A 1 548 ? 4.224   19.260  72.184  1.00 70.32  ? 623  HIS A CG  1 
ATOM   4215  N ND1 . HIS A 1 548 ? 4.920   20.388  71.806  1.00 71.89  ? 623  HIS A ND1 1 
ATOM   4216  C CD2 . HIS A 1 548 ? 4.428   19.119  73.515  1.00 66.63  ? 623  HIS A CD2 1 
ATOM   4217  C CE1 . HIS A 1 548 ? 5.525   20.901  72.862  1.00 86.79  ? 623  HIS A CE1 1 
ATOM   4218  N NE2 . HIS A 1 548 ? 5.242   20.151  73.912  1.00 76.73  ? 623  HIS A NE2 1 
ATOM   4219  N N   . THR A 1 549 ? 1.406   19.395  68.878  1.00 83.94  ? 624  THR A N   1 
ATOM   4220  C CA  . THR A 1 549 ? 1.042   19.159  67.489  1.00 90.15  ? 624  THR A CA  1 
ATOM   4221  C C   . THR A 1 549 ? 2.219   19.333  66.537  1.00 93.79  ? 624  THR A C   1 
ATOM   4222  O O   . THR A 1 549 ? 2.044   19.194  65.320  1.00 91.86  ? 624  THR A O   1 
ATOM   4223  C CB  . THR A 1 549 ? -0.095  20.097  67.068  1.00 94.88  ? 624  THR A CB  1 
ATOM   4224  O OG1 . THR A 1 549 ? 0.374   21.451  67.065  1.00 96.54  ? 624  THR A OG1 1 
ATOM   4225  C CG2 . THR A 1 549 ? -1.281  19.970  68.015  1.00 93.34  ? 624  THR A CG2 1 
ATOM   4226  N N   . ASP A 1 550 ? 3.407   19.638  67.054  1.00 99.03  ? 625  ASP A N   1 
ATOM   4227  C CA  . ASP A 1 550 ? 4.583   19.789  66.210  1.00 90.49  ? 625  ASP A CA  1 
ATOM   4228  C C   . ASP A 1 550 ? 5.054   18.427  65.719  1.00 84.99  ? 625  ASP A C   1 
ATOM   4229  O O   . ASP A 1 550 ? 5.123   17.465  66.492  1.00 82.82  ? 625  ASP A O   1 
ATOM   4230  C CB  . ASP A 1 550 ? 5.696   20.496  66.982  1.00 91.00  ? 625  ASP A CB  1 
ATOM   4231  C CG  . ASP A 1 550 ? 7.030   20.434  66.271  1.00 82.35  ? 625  ASP A CG  1 
ATOM   4232  O OD1 . ASP A 1 550 ? 7.096   20.832  65.090  1.00 89.35  ? 625  ASP A OD1 1 
ATOM   4233  O OD2 . ASP A 1 550 ? 8.015   19.985  66.892  1.00 79.46  ? 625  ASP A OD2 1 
ATOM   4234  N N   . THR A 1 551 ? 5.380   18.350  64.425  1.00 77.73  ? 626  THR A N   1 
ATOM   4235  C CA  . THR A 1 551 ? 5.772   17.075  63.831  1.00 82.31  ? 626  THR A CA  1 
ATOM   4236  C C   . THR A 1 551 ? 7.036   16.523  64.476  1.00 84.25  ? 626  THR A C   1 
ATOM   4237  O O   . THR A 1 551 ? 7.160   15.309  64.669  1.00 88.11  ? 626  THR A O   1 
ATOM   4238  C CB  . THR A 1 551 ? 5.980   17.231  62.323  1.00 72.93  ? 626  THR A CB  1 
ATOM   4239  O OG1 . THR A 1 551 ? 6.769   18.398  62.065  1.00 87.54  ? 626  THR A OG1 1 
ATOM   4240  C CG2 . THR A 1 551 ? 4.646   17.358  61.603  1.00 76.79  ? 626  THR A CG2 1 
ATOM   4241  N N   . ASP A 1 552 ? 7.990   17.397  64.809  1.00 81.63  ? 627  ASP A N   1 
ATOM   4242  C CA  . ASP A 1 552 ? 9.255   16.924  65.363  1.00 78.62  ? 627  ASP A CA  1 
ATOM   4243  C C   . ASP A 1 552 ? 9.070   16.338  66.757  1.00 79.92  ? 627  ASP A C   1 
ATOM   4244  O O   . ASP A 1 552 ? 9.694   15.326  67.095  1.00 81.07  ? 627  ASP A O   1 
ATOM   4245  C CB  . ASP A 1 552 ? 10.278  18.058  65.381  1.00 80.46  ? 627  ASP A CB  1 
ATOM   4246  C CG  . ASP A 1 552 ? 10.437  18.714  64.027  1.00 82.14  ? 627  ASP A CG  1 
ATOM   4247  O OD1 . ASP A 1 552 ? 10.951  18.047  63.105  1.00 63.90  ? 627  ASP A OD1 1 
ATOM   4248  O OD2 . ASP A 1 552 ? 10.043  19.891  63.881  1.00 80.87  ? 627  ASP A OD2 1 
ATOM   4249  N N   . VAL A 1 553 ? 8.210   16.949  67.575  1.00 82.99  ? 628  VAL A N   1 
ATOM   4250  C CA  . VAL A 1 553 ? 7.939   16.403  68.903  1.00 73.06  ? 628  VAL A CA  1 
ATOM   4251  C C   . VAL A 1 553 ? 7.329   15.013  68.787  1.00 78.06  ? 628  VAL A C   1 
ATOM   4252  O O   . VAL A 1 553 ? 7.781   14.061  69.433  1.00 73.58  ? 628  VAL A O   1 
ATOM   4253  C CB  . VAL A 1 553 ? 7.028   17.348  69.705  1.00 66.15  ? 628  VAL A CB  1 
ATOM   4254  C CG1 . VAL A 1 553 ? 6.698   16.734  71.056  1.00 75.47  ? 628  VAL A CG1 1 
ATOM   4255  C CG2 . VAL A 1 553 ? 7.688   18.702  69.882  1.00 70.74  ? 628  VAL A CG2 1 
ATOM   4256  N N   . LEU A 1 554 ? 6.290   14.880  67.959  1.00 77.17  ? 629  LEU A N   1 
ATOM   4257  C CA  . LEU A 1 554 ? 5.612   13.597  67.805  1.00 75.51  ? 629  LEU A CA  1 
ATOM   4258  C C   . LEU A 1 554 ? 6.554   12.541  67.236  1.00 76.42  ? 629  LEU A C   1 
ATOM   4259  O O   . LEU A 1 554 ? 6.518   11.373  67.649  1.00 64.51  ? 629  LEU A O   1 
ATOM   4260  C CB  . LEU A 1 554 ? 4.388   13.776  66.906  1.00 79.13  ? 629  LEU A CB  1 
ATOM   4261  C CG  . LEU A 1 554 ? 3.339   14.774  67.412  1.00 78.90  ? 629  LEU A CG  1 
ATOM   4262  C CD1 . LEU A 1 554 ? 2.112   14.783  66.512  1.00 74.27  ? 629  LEU A CD1 1 
ATOM   4263  C CD2 . LEU A 1 554 ? 2.947   14.490  68.858  1.00 72.17  ? 629  LEU A CD2 1 
ATOM   4264  N N   . GLU A 1 555 ? 7.407   12.939  66.287  1.00 74.23  ? 630  GLU A N   1 
ATOM   4265  C CA  . GLU A 1 555 ? 8.409   12.029  65.742  1.00 68.18  ? 630  GLU A CA  1 
ATOM   4266  C C   . GLU A 1 555 ? 9.365   11.554  66.824  1.00 73.70  ? 630  GLU A C   1 
ATOM   4267  O O   . GLU A 1 555 ? 9.660   10.359  66.926  1.00 71.47  ? 630  GLU A O   1 
ATOM   4268  C CB  . GLU A 1 555 ? 9.189   12.711  64.620  1.00 61.24  ? 630  GLU A CB  1 
ATOM   4269  C CG  . GLU A 1 555 ? 10.474  11.981  64.252  1.00 76.16  ? 630  GLU A CG  1 
ATOM   4270  C CD  . GLU A 1 555 ? 11.125  12.528  62.999  1.00 86.02  ? 630  GLU A CD  1 
ATOM   4271  O OE1 . GLU A 1 555 ? 10.558  13.462  62.395  1.00 75.09  ? 630  GLU A OE1 1 
ATOM   4272  O OE2 . GLU A 1 555 ? 12.206  12.025  62.620  1.00 84.63  ? 630  GLU A OE2 1 
ATOM   4273  N N   . ALA A 1 556 ? 9.882   12.486  67.628  1.00 72.14  ? 631  ALA A N   1 
ATOM   4274  C CA  . ALA A 1 556 ? 10.786  12.109  68.708  1.00 68.84  ? 631  ALA A CA  1 
ATOM   4275  C C   . ALA A 1 556 ? 10.097  11.182  69.698  1.00 70.34  ? 631  ALA A C   1 
ATOM   4276  O O   . ALA A 1 556 ? 10.721  10.257  70.227  1.00 67.70  ? 631  ALA A O   1 
ATOM   4277  C CB  . ALA A 1 556 ? 11.314  13.360  69.410  1.00 68.59  ? 631  ALA A CB  1 
ATOM   4278  N N   . CYS A 1 557 ? 8.802   11.398  69.943  1.00 69.47  ? 632  CYS A N   1 
ATOM   4279  C CA  . CYS A 1 557 ? 8.072   10.542  70.875  1.00 63.08  ? 632  CYS A CA  1 
ATOM   4280  C C   . CYS A 1 557 ? 7.929   9.125   70.333  1.00 58.98  ? 632  CYS A C   1 
ATOM   4281  O O   . CYS A 1 557 ? 8.166   8.146   71.053  1.00 68.84  ? 632  CYS A O   1 
ATOM   4282  C CB  . CYS A 1 557 ? 6.701   11.137  71.185  1.00 57.09  ? 632  CYS A CB  1 
ATOM   4283  S SG  . CYS A 1 557 ? 6.709   12.787  71.925  1.00 60.33  ? 632  CYS A SG  1 
ATOM   4284  N N   . SER A 1 558 ? 7.537   8.995   69.064  1.00 49.77  ? 633  SER A N   1 
ATOM   4285  C CA  . SER A 1 558 ? 7.424   7.661   68.478  1.00 64.48  ? 633  SER A CA  1 
ATOM   4286  C C   . SER A 1 558 ? 8.784   6.976   68.405  1.00 75.70  ? 633  SER A C   1 
ATOM   4287  O O   . SER A 1 558 ? 8.890   5.768   68.648  1.00 73.37  ? 633  SER A O   1 
ATOM   4288  C CB  . SER A 1 558 ? 6.781   7.741   67.094  1.00 59.87  ? 633  SER A CB  1 
ATOM   4289  O OG  . SER A 1 558 ? 7.680   8.272   66.138  1.00 74.07  ? 633  SER A OG  1 
ATOM   4290  N N   . LYS A 1 559 ? 9.839   7.736   68.096  1.00 71.63  ? 634  LYS A N   1 
ATOM   4291  C CA  . LYS A 1 559 ? 11.189  7.177   68.060  1.00 59.39  ? 634  LYS A CA  1 
ATOM   4292  C C   . LYS A 1 559 ? 11.609  6.674   69.437  1.00 66.21  ? 634  LYS A C   1 
ATOM   4293  O O   . LYS A 1 559 ? 12.189  5.589   69.569  1.00 77.14  ? 634  LYS A O   1 
ATOM   4294  C CB  . LYS A 1 559 ? 12.178  8.232   67.557  1.00 55.73  ? 634  LYS A CB  1 
ATOM   4295  C CG  . LYS A 1 559 ? 12.092  8.568   66.074  1.00 62.67  ? 634  LYS A CG  1 
ATOM   4296  C CD  . LYS A 1 559 ? 12.828  7.552   65.213  1.00 75.93  ? 634  LYS A CD  1 
ATOM   4297  C CE  . LYS A 1 559 ? 13.609  8.233   64.092  1.00 70.79  ? 634  LYS A CE  1 
ATOM   4298  N NZ  . LYS A 1 559 ? 12.845  9.339   63.450  1.00 68.82  ? 634  LYS A NZ  1 
ATOM   4299  N N   . THR A 1 560 ? 11.337  7.467   70.477  1.00 60.76  ? 635  THR A N   1 
ATOM   4300  C CA  . THR A 1 560 ? 11.690  7.073   71.835  1.00 62.10  ? 635  THR A CA  1 
ATOM   4301  C C   . THR A 1 560 ? 10.926  5.829   72.260  1.00 67.34  ? 635  THR A C   1 
ATOM   4302  O O   . THR A 1 560 ? 11.498  4.915   72.868  1.00 64.85  ? 635  THR A O   1 
ATOM   4303  C CB  . THR A 1 560 ? 11.411  8.227   72.798  1.00 53.68  ? 635  THR A CB  1 
ATOM   4304  O OG1 . THR A 1 560 ? 12.111  9.400   72.361  1.00 65.25  ? 635  THR A OG1 1 
ATOM   4305  C CG2 . THR A 1 560 ? 11.848  7.869   74.205  1.00 57.99  ? 635  THR A CG2 1 
ATOM   4306  N N   . TYR A 1 561 ? 9.629   5.775   71.948  1.00 64.97  ? 636  TYR A N   1 
ATOM   4307  C CA  . TYR A 1 561 ? 8.845   4.595   72.287  1.00 69.99  ? 636  TYR A CA  1 
ATOM   4308  C C   . TYR A 1 561 ? 9.358   3.368   71.544  1.00 72.70  ? 636  TYR A C   1 
ATOM   4309  O O   . TYR A 1 561 ? 9.394   2.265   72.102  1.00 76.94  ? 636  TYR A O   1 
ATOM   4310  C CB  . TYR A 1 561 ? 7.368   4.839   71.977  1.00 74.67  ? 636  TYR A CB  1 
ATOM   4311  C CG  . TYR A 1 561 ? 6.506   4.970   73.212  1.00 78.52  ? 636  TYR A CG  1 
ATOM   4312  C CD1 . TYR A 1 561 ? 6.194   3.861   73.988  1.00 68.05  ? 636  TYR A CD1 1 
ATOM   4313  C CD2 . TYR A 1 561 ? 6.009   6.207   73.605  1.00 70.35  ? 636  TYR A CD2 1 
ATOM   4314  C CE1 . TYR A 1 561 ? 5.408   3.980   75.119  1.00 77.12  ? 636  TYR A CE1 1 
ATOM   4315  C CE2 . TYR A 1 561 ? 5.224   6.336   74.732  1.00 75.01  ? 636  TYR A CE2 1 
ATOM   4316  C CZ  . TYR A 1 561 ? 4.926   5.220   75.487  1.00 87.30  ? 636  TYR A CZ  1 
ATOM   4317  O OH  . TYR A 1 561 ? 4.142   5.349   76.611  1.00 84.29  ? 636  TYR A OH  1 
ATOM   4318  N N   . HIS A 1 562 ? 9.768   3.544   70.285  1.00 69.69  ? 637  HIS A N   1 
ATOM   4319  C CA  . HIS A 1 562 ? 10.335  2.433   69.528  1.00 71.12  ? 637  HIS A CA  1 
ATOM   4320  C C   . HIS A 1 562 ? 11.634  1.944   70.152  1.00 69.91  ? 637  HIS A C   1 
ATOM   4321  O O   . HIS A 1 562 ? 11.861  0.734   70.263  1.00 74.73  ? 637  HIS A O   1 
ATOM   4322  C CB  . HIS A 1 562 ? 10.566  2.853   68.078  1.00 78.14  ? 637  HIS A CB  1 
ATOM   4323  C CG  . HIS A 1 562 ? 11.290  1.830   67.260  1.00 75.64  ? 637  HIS A CG  1 
ATOM   4324  N ND1 . HIS A 1 562 ? 12.326  2.156   66.411  1.00 68.62  ? 637  HIS A ND1 1 
ATOM   4325  C CD2 . HIS A 1 562 ? 11.122  0.491   67.153  1.00 77.85  ? 637  HIS A CD2 1 
ATOM   4326  C CE1 . HIS A 1 562 ? 12.770  1.060   65.822  1.00 84.89  ? 637  HIS A CE1 1 
ATOM   4327  N NE2 . HIS A 1 562 ? 12.057  0.036   66.254  1.00 90.17  ? 637  HIS A NE2 1 
ATOM   4328  N N   . ALA A 1 563 ? 12.503  2.872   70.558  1.00 72.69  ? 638  ALA A N   1 
ATOM   4329  C CA  . ALA A 1 563 ? 13.745  2.477   71.216  1.00 64.01  ? 638  ALA A CA  1 
ATOM   4330  C C   . ALA A 1 563 ? 13.462  1.751   72.523  1.00 67.25  ? 638  ALA A C   1 
ATOM   4331  O O   . ALA A 1 563 ? 14.155  0.788   72.873  1.00 72.25  ? 638  ALA A O   1 
ATOM   4332  C CB  . ALA A 1 563 ? 14.625  3.700   71.462  1.00 51.26  ? 638  ALA A CB  1 
ATOM   4333  N N   . LEU A 1 564 ? 12.437  2.192   73.255  1.00 64.65  ? 639  LEU A N   1 
ATOM   4334  C CA  . LEU A 1 564 ? 12.117  1.560   74.529  1.00 67.39  ? 639  LEU A CA  1 
ATOM   4335  C C   . LEU A 1 564 ? 11.446  0.203   74.340  1.00 77.48  ? 639  LEU A C   1 
ATOM   4336  O O   . LEU A 1 564 ? 11.599  -0.684  75.187  1.00 84.36  ? 639  LEU A O   1 
ATOM   4337  C CB  . LEU A 1 564 ? 11.234  2.490   75.360  1.00 66.15  ? 639  LEU A CB  1 
ATOM   4338  C CG  . LEU A 1 564 ? 11.891  3.768   75.889  1.00 62.88  ? 639  LEU A CG  1 
ATOM   4339  C CD1 . LEU A 1 564 ? 10.836  4.790   76.273  1.00 55.52  ? 639  LEU A CD1 1 
ATOM   4340  C CD2 . LEU A 1 564 ? 12.786  3.462   77.079  1.00 64.13  ? 639  LEU A CD2 1 
ATOM   4341  N N   . CYS A 1 565 ? 10.712  0.015   73.241  1.00 71.39  ? 640  CYS A N   1 
ATOM   4342  C CA  . CYS A 1 565 ? 10.015  -1.245  72.977  1.00 65.41  ? 640  CYS A CA  1 
ATOM   4343  C C   . CYS A 1 565 ? 10.985  -2.232  72.329  1.00 78.98  ? 640  CYS A C   1 
ATOM   4344  O O   . CYS A 1 565 ? 10.962  -2.477  71.121  1.00 82.02  ? 640  CYS A O   1 
ATOM   4345  C CB  . CYS A 1 565 ? 8.795   -1.013  72.094  1.00 85.37  ? 640  CYS A CB  1 
ATOM   4346  S SG  . CYS A 1 565 ? 7.398   -0.198  72.894  1.00 95.67  ? 640  CYS A SG  1 
ATOM   4347  N N   . ASN A 1 566 ? 11.851  -2.815  73.156  1.00 89.51  ? 641  ASN A N   1 
ATOM   4348  C CA  . ASN A 1 566 ? 12.798  -3.837  72.719  1.00 94.87  ? 641  ASN A CA  1 
ATOM   4349  C C   . ASN A 1 566 ? 12.432  -5.147  73.404  1.00 96.70  ? 641  ASN A C   1 
ATOM   4350  O O   . ASN A 1 566 ? 12.578  -5.273  74.624  1.00 116.30 ? 641  ASN A O   1 
ATOM   4351  C CB  . ASN A 1 566 ? 14.233  -3.429  73.041  1.00 99.08  ? 641  ASN A CB  1 
ATOM   4352  C CG  . ASN A 1 566 ? 14.970  -2.882  71.835  1.00 103.37 ? 641  ASN A CG  1 
ATOM   4353  O OD1 . ASN A 1 566 ? 14.812  -3.381  70.721  1.00 111.55 ? 641  ASN A OD1 1 
ATOM   4354  N ND2 . ASN A 1 566 ? 15.788  -1.857  72.051  1.00 105.53 ? 641  ASN A ND2 1 
ATOM   4355  N N   . GLU A 1 567 ? 11.961  -6.121  72.617  1.00 86.24  ? 642  GLU A N   1 
ATOM   4356  C CA  . GLU A 1 567 ? 11.563  -7.407  73.182  1.00 103.02 ? 642  GLU A CA  1 
ATOM   4357  C C   . GLU A 1 567 ? 12.689  -8.045  73.986  1.00 112.93 ? 642  GLU A C   1 
ATOM   4358  O O   . GLU A 1 567 ? 12.430  -8.735  74.979  1.00 124.85 ? 642  GLU A O   1 
ATOM   4359  C CB  . GLU A 1 567 ? 11.109  -8.360  72.071  1.00 118.49 ? 642  GLU A CB  1 
ATOM   4360  C CG  . GLU A 1 567 ? 9.695   -8.131  71.556  1.00 115.33 ? 642  GLU A CG  1 
ATOM   4361  C CD  . GLU A 1 567 ? 9.654   -7.271  70.307  1.00 110.34 ? 642  GLU A CD  1 
ATOM   4362  O OE1 . GLU A 1 567 ? 10.273  -6.186  70.311  1.00 109.47 ? 642  GLU A OE1 1 
ATOM   4363  O OE2 . GLU A 1 567 ? 9.006   -7.684  69.319  1.00 136.50 ? 642  GLU A OE2 1 
ATOM   4364  N N   . GLU A 1 568 ? 13.942  -7.817  73.582  1.00 117.51 ? 643  GLU A N   1 
ATOM   4365  C CA  . GLU A 1 568 ? 15.076  -8.407  74.282  1.00 117.44 ? 643  GLU A CA  1 
ATOM   4366  C C   . GLU A 1 568 ? 15.343  -7.776  75.646  1.00 118.27 ? 643  GLU A C   1 
ATOM   4367  O O   . GLU A 1 568 ? 15.896  -8.457  76.517  1.00 130.18 ? 643  GLU A O   1 
ATOM   4368  C CB  . GLU A 1 568 ? 16.318  -8.345  73.383  1.00 126.23 ? 643  GLU A CB  1 
ATOM   4369  C CG  . GLU A 1 568 ? 16.594  -7.002  72.746  1.00 143.45 ? 643  GLU A CG  1 
ATOM   4370  C CD  . GLU A 1 568 ? 17.355  -6.055  73.636  1.00 168.11 ? 643  GLU A CD  1 
ATOM   4371  O OE1 . GLU A 1 568 ? 17.829  -6.477  74.711  1.00 209.27 ? 643  GLU A OE1 1 
ATOM   4372  O OE2 . GLU A 1 568 ? 17.514  -4.883  73.233  1.00 186.04 ? 643  GLU A OE2 1 
ATOM   4373  N N   . PHE A 1 569 ? 14.960  -6.518  75.858  1.00 114.64 ? 644  PHE A N   1 
ATOM   4374  C CA  . PHE A 1 569 ? 15.034  -5.920  77.186  1.00 118.35 ? 644  PHE A CA  1 
ATOM   4375  C C   . PHE A 1 569 ? 13.781  -6.256  77.989  1.00 101.81 ? 644  PHE A C   1 
ATOM   4376  O O   . PHE A 1 569 ? 12.687  -6.406  77.440  1.00 112.95 ? 644  PHE A O   1 
ATOM   4377  C CB  . PHE A 1 569 ? 15.207  -4.400  77.111  1.00 121.08 ? 644  PHE A CB  1 
ATOM   4378  C CG  . PHE A 1 569 ? 16.586  -3.970  76.704  1.00 125.20 ? 644  PHE A CG  1 
ATOM   4379  C CD1 . PHE A 1 569 ? 17.685  -4.319  77.472  1.00 128.84 ? 644  PHE A CD1 1 
ATOM   4380  C CD2 . PHE A 1 569 ? 16.784  -3.219  75.549  1.00 123.94 ? 644  PHE A CD2 1 
ATOM   4381  C CE1 . PHE A 1 569 ? 18.959  -3.925  77.106  1.00 137.52 ? 644  PHE A CE1 1 
ATOM   4382  C CE2 . PHE A 1 569 ? 18.050  -2.820  75.176  1.00 130.27 ? 644  PHE A CE2 1 
ATOM   4383  C CZ  . PHE A 1 569 ? 19.143  -3.176  75.951  1.00 140.52 ? 644  PHE A CZ  1 
ATOM   4384  N N   . THR A 1 570 ? 13.954  -6.360  79.308  1.00 95.68  ? 645  THR A N   1 
ATOM   4385  C CA  . THR A 1 570 ? 12.868  -6.811  80.173  1.00 94.17  ? 645  THR A CA  1 
ATOM   4386  C C   . THR A 1 570 ? 11.789  -5.746  80.332  1.00 103.96 ? 645  THR A C   1 
ATOM   4387  O O   . THR A 1 570 ? 10.622  -6.075  80.579  1.00 98.23  ? 645  THR A O   1 
ATOM   4388  C CB  . THR A 1 570 ? 13.432  -7.209  81.536  1.00 81.92  ? 645  THR A CB  1 
ATOM   4389  O OG1 . THR A 1 570 ? 14.565  -8.069  81.352  1.00 82.53  ? 645  THR A OG1 1 
ATOM   4390  C CG2 . THR A 1 570 ? 12.385  -7.929  82.361  1.00 84.96  ? 645  THR A CG2 1 
ATOM   4391  N N   . ILE A 1 571 ? 12.151  -4.468  80.184  1.00 97.76  ? 646  ILE A N   1 
ATOM   4392  C CA  . ILE A 1 571 ? 11.175  -3.392  80.317  1.00 90.69  ? 646  ILE A CA  1 
ATOM   4393  C C   . ILE A 1 571 ? 10.128  -3.425  79.209  1.00 91.99  ? 646  ILE A C   1 
ATOM   4394  O O   . ILE A 1 571 ? 9.057   -2.821  79.364  1.00 91.71  ? 646  ILE A O   1 
ATOM   4395  C CB  . ILE A 1 571 ? 11.888  -2.022  80.368  1.00 74.62  ? 646  ILE A CB  1 
ATOM   4396  C CG1 . ILE A 1 571 ? 12.515  -1.687  79.011  1.00 86.81  ? 646  ILE A CG1 1 
ATOM   4397  C CG2 . ILE A 1 571 ? 12.887  -1.970  81.501  1.00 85.75  ? 646  ILE A CG2 1 
ATOM   4398  C CD1 . ILE A 1 571 ? 12.536  -0.209  78.692  1.00 77.51  ? 646  ILE A CD1 1 
ATOM   4399  N N   . PHE A 1 572 ? 10.408  -4.134  78.105  1.00 90.94  ? 647  PHE A N   1 
ATOM   4400  C CA  . PHE A 1 572 ? 9.531   -4.171  76.938  1.00 89.37  ? 647  PHE A CA  1 
ATOM   4401  C C   . PHE A 1 572 ? 8.059   -4.176  77.316  1.00 92.00  ? 647  PHE A C   1 
ATOM   4402  O O   . PHE A 1 572 ? 7.330   -3.215  77.037  1.00 96.92  ? 647  PHE A O   1 
ATOM   4403  C CB  . PHE A 1 572 ? 9.830   -5.400  76.078  1.00 96.32  ? 647  PHE A CB  1 
ATOM   4404  C CG  . PHE A 1 572 ? 8.865   -5.577  74.942  1.00 104.18 ? 647  PHE A CG  1 
ATOM   4405  C CD1 . PHE A 1 572 ? 8.693   -4.576  73.999  1.00 107.94 ? 647  PHE A CD1 1 
ATOM   4406  C CD2 . PHE A 1 572 ? 8.106   -6.728  74.836  1.00 93.70  ? 647  PHE A CD2 1 
ATOM   4407  C CE1 . PHE A 1 572 ? 7.791   -4.729  72.960  1.00 102.58 ? 647  PHE A CE1 1 
ATOM   4408  C CE2 . PHE A 1 572 ? 7.205   -6.889  73.801  1.00 90.40  ? 647  PHE A CE2 1 
ATOM   4409  C CZ  . PHE A 1 572 ? 7.047   -5.889  72.861  1.00 98.56  ? 647  PHE A CZ  1 
ATOM   4410  N N   . ASN A 1 573 ? 7.625   -5.254  77.979  1.00 90.09  ? 648  ASN A N   1 
ATOM   4411  C CA  . ASN A 1 573 ? 6.236   -5.414  78.389  1.00 93.62  ? 648  ASN A CA  1 
ATOM   4412  C C   . ASN A 1 573 ? 5.660   -4.105  78.912  1.00 88.01  ? 648  ASN A C   1 
ATOM   4413  O O   . ASN A 1 573 ? 4.727   -3.549  78.317  1.00 80.23  ? 648  ASN A O   1 
ATOM   4414  C CB  . ASN A 1 573 ? 6.127   -6.516  79.445  1.00 90.86  ? 648  ASN A CB  1 
ATOM   4415  C CG  . ASN A 1 573 ? 4.694   -6.774  79.866  1.00 113.00 ? 648  ASN A CG  1 
ATOM   4416  O OD1 . ASN A 1 573 ? 4.377   -6.786  81.055  1.00 127.98 ? 648  ASN A OD1 1 
ATOM   4417  N ND2 . ASN A 1 573 ? 3.820   -6.992  78.889  1.00 115.87 ? 648  ASN A ND2 1 
ATOM   4418  N N   . ARG A 1 574 ? 6.249   -3.572  79.990  1.00 82.29  ? 649  ARG A N   1 
ATOM   4419  C CA  . ARG A 1 574 ? 5.766   -2.315  80.553  1.00 84.66  ? 649  ARG A CA  1 
ATOM   4420  C C   . ARG A 1 574 ? 5.580   -1.275  79.459  1.00 91.47  ? 649  ARG A C   1 
ATOM   4421  O O   . ARG A 1 574 ? 4.454   -0.844  79.178  1.00 96.73  ? 649  ARG A O   1 
ATOM   4422  C CB  . ARG A 1 574 ? 6.724   -1.794  81.628  1.00 74.48  ? 649  ARG A CB  1 
ATOM   4423  C CG  . ARG A 1 574 ? 7.629   -2.842  82.244  1.00 92.46  ? 649  ARG A CG  1 
ATOM   4424  C CD  . ARG A 1 574 ? 8.578   -2.211  83.256  1.00 95.56  ? 649  ARG A CD  1 
ATOM   4425  N NE  . ARG A 1 574 ? 7.896   -1.246  84.111  1.00 86.24  ? 649  ARG A NE  1 
ATOM   4426  C CZ  . ARG A 1 574 ? 7.467   -1.499  85.340  1.00 92.62  ? 649  ARG A CZ  1 
ATOM   4427  N NH1 . ARG A 1 574 ? 7.652   -2.680  85.907  1.00 104.56 ? 649  ARG A NH1 1 
ATOM   4428  N NH2 . ARG A 1 574 ? 6.834   -0.545  86.017  1.00 85.04  ? 649  ARG A NH2 1 
ATOM   4429  N N   . VAL A 1 575 ? 6.677   -0.914  78.786  1.00 92.60  ? 650  VAL A N   1 
ATOM   4430  C CA  . VAL A 1 575 ? 6.603   0.091   77.730  1.00 94.79  ? 650  VAL A CA  1 
ATOM   4431  C C   . VAL A 1 575 ? 5.517   -0.289  76.735  1.00 98.51  ? 650  VAL A C   1 
ATOM   4432  O O   . VAL A 1 575 ? 4.613   0.506   76.444  1.00 97.37  ? 650  VAL A O   1 
ATOM   4433  C CB  . VAL A 1 575 ? 7.972   0.255   77.046  1.00 83.14  ? 650  VAL A CB  1 
ATOM   4434  C CG1 . VAL A 1 575 ? 7.906   1.322   75.967  1.00 85.25  ? 650  VAL A CG1 1 
ATOM   4435  C CG2 . VAL A 1 575 ? 9.041   0.576   78.075  1.00 72.52  ? 650  VAL A CG2 1 
ATOM   4436  N N   . ASP A 1 576 ? 5.549   -1.543  76.264  1.00 103.54 ? 651  ASP A N   1 
ATOM   4437  C CA  . ASP A 1 576 ? 4.567   -1.990  75.282  1.00 102.80 ? 651  ASP A CA  1 
ATOM   4438  C C   . ASP A 1 576 ? 3.159   -1.688  75.770  1.00 94.53  ? 651  ASP A C   1 
ATOM   4439  O O   . ASP A 1 576 ? 2.376   -1.033  75.069  1.00 89.93  ? 651  ASP A O   1 
ATOM   4440  C CB  . ASP A 1 576 ? 4.744   -3.485  74.992  1.00 99.29  ? 651  ASP A CB  1 
ATOM   4441  C CG  . ASP A 1 576 ? 3.531   -4.097  74.314  1.00 91.17  ? 651  ASP A CG  1 
ATOM   4442  O OD1 . ASP A 1 576 ? 3.262   -3.742  73.147  1.00 98.40  ? 651  ASP A OD1 1 
ATOM   4443  O OD2 . ASP A 1 576 ? 2.857   -4.940  74.943  1.00 90.55  ? 651  ASP A OD2 1 
ATOM   4444  N N   . ILE A 1 577 ? 2.852   -2.093  77.009  1.00 91.80  ? 652  ILE A N   1 
ATOM   4445  C CA  . ILE A 1 577 ? 1.540   -1.808  77.586  1.00 92.23  ? 652  ILE A CA  1 
ATOM   4446  C C   . ILE A 1 577 ? 1.219   -0.328  77.438  1.00 88.36  ? 652  ILE A C   1 
ATOM   4447  O O   . ILE A 1 577 ? 0.248   0.051   76.769  1.00 100.25 ? 652  ILE A O   1 
ATOM   4448  C CB  . ILE A 1 577 ? 1.482   -2.255  79.056  1.00 80.42  ? 652  ILE A CB  1 
ATOM   4449  C CG1 . ILE A 1 577 ? 1.500   -3.781  79.141  1.00 85.01  ? 652  ILE A CG1 1 
ATOM   4450  C CG2 . ILE A 1 577 ? 0.226   -1.715  79.720  1.00 75.33  ? 652  ILE A CG2 1 
ATOM   4451  C CD1 . ILE A 1 577 ? 1.805   -4.317  80.515  1.00 81.75  ? 652  ILE A CD1 1 
ATOM   4452  N N   . SER A 1 578 ? 2.073   0.530   78.007  1.00 87.08  ? 653  SER A N   1 
ATOM   4453  C CA  . SER A 1 578 ? 1.852   1.967   77.895  1.00 90.76  ? 653  SER A CA  1 
ATOM   4454  C C   . SER A 1 578 ? 1.652   2.365   76.441  1.00 90.45  ? 653  SER A C   1 
ATOM   4455  O O   . SER A 1 578 ? 0.662   3.026   76.100  1.00 93.48  ? 653  SER A O   1 
ATOM   4456  C CB  . SER A 1 578 ? 3.016   2.737   78.520  1.00 100.15 ? 653  SER A CB  1 
ATOM   4457  O OG  . SER A 1 578 ? 4.224   2.501   77.821  1.00 102.76 ? 653  SER A OG  1 
ATOM   4458  N N   . ARG A 1 579 ? 2.545   1.902   75.557  1.00 97.60  ? 654  ARG A N   1 
ATOM   4459  C CA  . ARG A 1 579 ? 2.406   2.219   74.141  1.00 97.73  ? 654  ARG A CA  1 
ATOM   4460  C C   . ARG A 1 579 ? 0.993   1.905   73.669  1.00 94.35  ? 654  ARG A C   1 
ATOM   4461  O O   . ARG A 1 579 ? 0.272   2.796   73.200  1.00 96.34  ? 654  ARG A O   1 
ATOM   4462  C CB  . ARG A 1 579 ? 3.446   1.457   73.313  1.00 93.62  ? 654  ARG A CB  1 
ATOM   4463  C CG  . ARG A 1 579 ? 3.010   1.228   71.873  1.00 78.37  ? 654  ARG A CG  1 
ATOM   4464  C CD  . ARG A 1 579 ? 4.098   0.680   70.963  1.00 66.06  ? 654  ARG A CD  1 
ATOM   4465  N NE  . ARG A 1 579 ? 4.272   -0.760  71.101  1.00 84.78  ? 654  ARG A NE  1 
ATOM   4466  C CZ  . ARG A 1 579 ? 5.151   -1.475  70.413  1.00 93.71  ? 654  ARG A CZ  1 
ATOM   4467  N NH1 . ARG A 1 579 ? 5.935   -0.918  69.504  1.00 74.40  ? 654  ARG A NH1 1 
ATOM   4468  N NH2 . ARG A 1 579 ? 5.244   -2.782  70.640  1.00 106.98 ? 654  ARG A NH2 1 
ATOM   4469  N N   . SER A 1 580 ? 0.552   0.659   73.883  1.00 91.19  ? 655  SER A N   1 
ATOM   4470  C CA  . SER A 1 580 ? -0.786  0.262   73.459  1.00 92.96  ? 655  SER A CA  1 
ATOM   4471  C C   . SER A 1 580 ? -1.825  1.248   73.970  1.00 93.89  ? 655  SER A C   1 
ATOM   4472  O O   . SER A 1 580 ? -2.605  1.805   73.186  1.00 100.01 ? 655  SER A O   1 
ATOM   4473  C CB  . SER A 1 580 ? -1.102  -1.156  73.943  1.00 82.15  ? 655  SER A CB  1 
ATOM   4474  O OG  . SER A 1 580 ? -1.413  -1.175  75.326  1.00 109.15 ? 655  SER A OG  1 
ATOM   4475  N N   . GLN A 1 581 ? -1.797  1.527   75.280  1.00 84.20  ? 656  GLN A N   1 
ATOM   4476  C CA  . GLN A 1 581 ? -2.779  2.434   75.863  1.00 76.64  ? 656  GLN A CA  1 
ATOM   4477  C C   . GLN A 1 581 ? -2.839  3.727   75.070  1.00 85.25  ? 656  GLN A C   1 
ATOM   4478  O O   . GLN A 1 581 ? -3.908  4.118   74.578  1.00 101.89 ? 656  GLN A O   1 
ATOM   4479  C CB  . GLN A 1 581 ? -2.448  2.717   77.330  1.00 78.89  ? 656  GLN A CB  1 
ATOM   4480  C CG  . GLN A 1 581 ? -2.611  1.521   78.250  1.00 83.30  ? 656  GLN A CG  1 
ATOM   4481  C CD  . GLN A 1 581 ? -1.903  1.708   79.579  1.00 99.46  ? 656  GLN A CD  1 
ATOM   4482  O OE1 . GLN A 1 581 ? -1.117  2.640   79.753  1.00 112.30 ? 656  GLN A OE1 1 
ATOM   4483  N NE2 . GLN A 1 581 ? -2.174  0.814   80.523  1.00 94.94  ? 656  GLN A NE2 1 
ATOM   4484  N N   . LEU A 1 582 ? -1.677  4.358   74.869  1.00 91.20  ? 657  LEU A N   1 
ATOM   4485  C CA  . LEU A 1 582 ? -1.626  5.602   74.113  1.00 90.91  ? 657  LEU A CA  1 
ATOM   4486  C C   . LEU A 1 582 ? -2.372  5.439   72.800  1.00 89.18  ? 657  LEU A C   1 
ATOM   4487  O O   . LEU A 1 582 ? -3.393  6.101   72.562  1.00 96.85  ? 657  LEU A O   1 
ATOM   4488  C CB  . LEU A 1 582 ? -0.171  6.018   73.876  1.00 89.75  ? 657  LEU A CB  1 
ATOM   4489  C CG  . LEU A 1 582 ? 0.063   7.391   73.244  1.00 86.28  ? 657  LEU A CG  1 
ATOM   4490  C CD1 . LEU A 1 582 ? -0.659  8.457   74.045  1.00 93.61  ? 657  LEU A CD1 1 
ATOM   4491  C CD2 . LEU A 1 582 ? 1.551   7.693   73.174  1.00 74.14  ? 657  LEU A CD2 1 
ATOM   4492  N N   . ILE A 1 583 ? -1.930  4.474   71.987  1.00 89.71  ? 658  ILE A N   1 
ATOM   4493  C CA  . ILE A 1 583 ? -2.562  4.251   70.692  1.00 93.07  ? 658  ILE A CA  1 
ATOM   4494  C C   . ILE A 1 583 ? -4.063  4.121   70.876  1.00 93.27  ? 658  ILE A C   1 
ATOM   4495  O O   . ILE A 1 583 ? -4.844  4.882   70.287  1.00 91.83  ? 658  ILE A O   1 
ATOM   4496  C CB  . ILE A 1 583 ? -1.972  3.008   70.008  1.00 93.90  ? 658  ILE A CB  1 
ATOM   4497  C CG1 . ILE A 1 583 ? -0.454  3.119   69.936  1.00 92.59  ? 658  ILE A CG1 1 
ATOM   4498  C CG2 . ILE A 1 583 ? -2.530  2.870   68.605  1.00 91.49  ? 658  ILE A CG2 1 
ATOM   4499  C CD1 . ILE A 1 583 ? 0.220   1.788   69.965  1.00 112.63 ? 658  ILE A CD1 1 
ATOM   4500  N N   . ASP A 1 584 ? -4.476  3.211   71.769  1.00 94.07  ? 659  ASP A N   1 
ATOM   4501  C CA  . ASP A 1 584 ? -5.894  2.996   72.032  1.00 86.60  ? 659  ASP A CA  1 
ATOM   4502  C C   . ASP A 1 584 ? -6.613  4.326   72.159  1.00 88.64  ? 659  ASP A C   1 
ATOM   4503  O O   . ASP A 1 584 ? -7.461  4.671   71.323  1.00 93.36  ? 659  ASP A O   1 
ATOM   4504  C CB  . ASP A 1 584 ? -6.087  2.159   73.300  1.00 69.43  ? 659  ASP A CB  1 
ATOM   4505  C CG  . ASP A 1 584 ? -5.849  0.684   73.068  1.00 84.97  ? 659  ASP A CG  1 
ATOM   4506  O OD1 . ASP A 1 584 ? -6.486  0.120   72.154  1.00 106.95 ? 659  ASP A OD1 1 
ATOM   4507  O OD2 . ASP A 1 584 ? -5.042  0.085   73.807  1.00 96.26  ? 659  ASP A OD2 1 
ATOM   4508  N N   . GLU A 1 585 ? -6.201  5.130   73.144  1.00 69.95  ? 660  GLU A N   1 
ATOM   4509  C CA  . GLU A 1 585 ? -6.887  6.391   73.382  1.00 82.03  ? 660  GLU A CA  1 
ATOM   4510  C C   . GLU A 1 585 ? -6.921  7.210   72.102  1.00 86.46  ? 660  GLU A C   1 
ATOM   4511  O O   . GLU A 1 585 ? -8.003  7.528   71.586  1.00 94.07  ? 660  GLU A O   1 
ATOM   4512  C CB  . GLU A 1 585 ? -6.209  7.151   74.526  1.00 81.54  ? 660  GLU A CB  1 
ATOM   4513  C CG  . GLU A 1 585 ? -6.875  8.466   74.900  1.00 121.12 ? 660  GLU A CG  1 
ATOM   4514  C CD  . GLU A 1 585 ? -6.403  8.987   76.246  1.00 149.08 ? 660  GLU A CD  1 
ATOM   4515  O OE1 . GLU A 1 585 ? -5.556  8.320   76.876  1.00 212.52 ? 660  GLU A OE1 1 
ATOM   4516  O OE2 . GLU A 1 585 ? -6.899  10.045  76.690  1.00 176.81 ? 660  GLU A OE2 1 
ATOM   4517  N N   . LEU A 1 586 ? -5.743  7.463   71.517  1.00 94.00  ? 661  LEU A N   1 
ATOM   4518  C CA  . LEU A 1 586 ? -5.681  8.190   70.255  1.00 91.31  ? 661  LEU A CA  1 
ATOM   4519  C C   . LEU A 1 586 ? -6.670  7.611   69.258  1.00 90.25  ? 661  LEU A C   1 
ATOM   4520  O O   . LEU A 1 586 ? -7.592  8.306   68.810  1.00 100.47 ? 661  LEU A O   1 
ATOM   4521  C CB  . LEU A 1 586 ? -4.260  8.157   69.693  1.00 84.83  ? 661  LEU A CB  1 
ATOM   4522  C CG  . LEU A 1 586 ? -3.255  9.081   70.379  1.00 82.94  ? 661  LEU A CG  1 
ATOM   4523  C CD1 . LEU A 1 586 ? -1.871  8.855   69.806  1.00 82.49  ? 661  LEU A CD1 1 
ATOM   4524  C CD2 . LEU A 1 586 ? -3.667  10.542  70.245  1.00 93.89  ? 661  LEU A CD2 1 
ATOM   4525  N N   . ALA A 1 587 ? -6.543  6.308   68.971  1.00 86.04  ? 662  ALA A N   1 
ATOM   4526  C CA  . ALA A 1 587 ? -7.423  5.671   67.999  1.00 89.77  ? 662  ALA A CA  1 
ATOM   4527  C C   . ALA A 1 587 ? -8.874  6.005   68.294  1.00 98.80  ? 662  ALA A C   1 
ATOM   4528  O O   . ALA A 1 587 ? -9.578  6.569   67.444  1.00 83.62  ? 662  ALA A O   1 
ATOM   4529  C CB  . ALA A 1 587 ? -7.212  4.157   67.995  1.00 83.79  ? 662  ALA A CB  1 
ATOM   4530  N N   . ASP A 1 588 ? -9.314  5.737   69.528  1.00 98.17  ? 663  ASP A N   1 
ATOM   4531  C CA  . ASP A 1 588 ? -10.705 5.994   69.877  1.00 95.18  ? 663  ASP A CA  1 
ATOM   4532  C C   . ASP A 1 588 ? -11.074 7.423   69.529  1.00 86.68  ? 663  ASP A C   1 
ATOM   4533  O O   . ASP A 1 588 ? -11.972 7.662   68.710  1.00 95.64  ? 663  ASP A O   1 
ATOM   4534  C CB  . ASP A 1 588 ? -10.941 5.708   71.360  1.00 111.39 ? 663  ASP A CB  1 
ATOM   4535  C CG  . ASP A 1 588 ? -10.650 4.267   71.721  1.00 127.52 ? 663  ASP A CG  1 
ATOM   4536  O OD1 . ASP A 1 588 ? -10.407 3.463   70.794  1.00 127.22 ? 663  ASP A OD1 1 
ATOM   4537  O OD2 . ASP A 1 588 ? -10.684 3.934   72.924  1.00 133.78 ? 663  ASP A OD2 1 
ATOM   4538  N N   . LYS A 1 589 ? -10.318 8.384   70.072  1.00 87.56  ? 664  LYS A N   1 
ATOM   4539  C CA  . LYS A 1 589 ? -10.572 9.787   69.774  1.00 85.65  ? 664  LYS A CA  1 
ATOM   4540  C C   . LYS A 1 589 ? -10.693 9.990   68.273  1.00 87.34  ? 664  LYS A C   1 
ATOM   4541  O O   . LYS A 1 589 ? -11.732 10.448  67.777  1.00 85.42  ? 664  LYS A O   1 
ATOM   4542  C CB  . LYS A 1 589 ? -9.455  10.657  70.356  1.00 86.67  ? 664  LYS A CB  1 
ATOM   4543  C CG  . LYS A 1 589 ? -9.545  12.128  69.994  1.00 111.22 ? 664  LYS A CG  1 
ATOM   4544  C CD  . LYS A 1 589 ? -8.899  12.983  71.075  1.00 129.65 ? 664  LYS A CD  1 
ATOM   4545  C CE  . LYS A 1 589 ? -9.395  14.420  71.034  1.00 142.09 ? 664  LYS A CE  1 
ATOM   4546  N NZ  . LYS A 1 589 ? -8.297  15.410  71.221  1.00 143.11 ? 664  LYS A NZ  1 
ATOM   4547  N N   . PHE A 1 590 ? -9.669  9.557   67.530  1.00 98.65  ? 665  PHE A N   1 
ATOM   4548  C CA  . PHE A 1 590 ? -9.664  9.748   66.086  1.00 100.97 ? 665  PHE A CA  1 
ATOM   4549  C C   . PHE A 1 590 ? -10.955 9.222   65.483  1.00 96.06  ? 665  PHE A C   1 
ATOM   4550  O O   . PHE A 1 590 ? -11.687 9.962   64.812  1.00 108.94 ? 665  PHE A O   1 
ATOM   4551  C CB  . PHE A 1 590 ? -8.445  9.058   65.472  1.00 95.16  ? 665  PHE A CB  1 
ATOM   4552  C CG  . PHE A 1 590 ? -8.220  9.388   64.023  1.00 85.77  ? 665  PHE A CG  1 
ATOM   4553  C CD1 . PHE A 1 590 ? -8.041  10.702  63.625  1.00 82.66  ? 665  PHE A CD1 1 
ATOM   4554  C CD2 . PHE A 1 590 ? -8.154  8.388   63.067  1.00 81.99  ? 665  PHE A CD2 1 
ATOM   4555  C CE1 . PHE A 1 590 ? -7.824  11.016  62.300  1.00 78.50  ? 665  PHE A CE1 1 
ATOM   4556  C CE2 . PHE A 1 590 ? -7.932  8.697   61.738  1.00 68.83  ? 665  PHE A CE2 1 
ATOM   4557  C CZ  . PHE A 1 590 ? -7.768  10.014  61.354  1.00 66.01  ? 665  PHE A CZ  1 
ATOM   4558  N N   . ASN A 1 591 ? -11.295 7.966   65.793  1.00 92.85  ? 666  ASN A N   1 
ATOM   4559  C CA  . ASN A 1 591 ? -12.506 7.376   65.236  1.00 107.46 ? 666  ASN A CA  1 
ATOM   4560  C C   . ASN A 1 591 ? -13.707 8.265   65.523  1.00 105.09 ? 666  ASN A C   1 
ATOM   4561  O O   . ASN A 1 591 ? -14.408 8.697   64.599  1.00 95.72  ? 666  ASN A O   1 
ATOM   4562  C CB  . ASN A 1 591 ? -12.712 5.967   65.792  1.00 106.74 ? 666  ASN A CB  1 
ATOM   4563  C CG  . ASN A 1 591 ? -11.895 4.925   65.051  1.00 92.00  ? 666  ASN A CG  1 
ATOM   4564  O OD1 . ASN A 1 591 ? -12.442 4.000   64.451  1.00 90.18  ? 666  ASN A OD1 1 
ATOM   4565  N ND2 . ASN A 1 591 ? -10.577 5.073   65.089  1.00 91.87  ? 666  ASN A ND2 1 
ATOM   4566  N N   . ARG A 1 592 ? -13.907 8.615   66.799  1.00 100.27 ? 667  ARG A N   1 
ATOM   4567  C CA  . ARG A 1 592 ? -15.020 9.489   67.149  1.00 97.63  ? 667  ARG A CA  1 
ATOM   4568  C C   . ARG A 1 592 ? -14.970 10.767  66.330  1.00 94.81  ? 667  ARG A C   1 
ATOM   4569  O O   . ARG A 1 592 ? -15.946 11.124  65.656  1.00 106.64 ? 667  ARG A O   1 
ATOM   4570  C CB  . ARG A 1 592 ? -15.003 9.799   68.646  1.00 92.50  ? 667  ARG A CB  1 
ATOM   4571  C CG  . ARG A 1 592 ? -15.235 8.592   69.546  1.00 100.84 ? 667  ARG A CG  1 
ATOM   4572  C CD  . ARG A 1 592 ? -16.323 7.672   69.002  1.00 110.53 ? 667  ARG A CD  1 
ATOM   4573  N NE  . ARG A 1 592 ? -15.778 6.486   68.352  1.00 120.74 ? 667  ARG A NE  1 
ATOM   4574  C CZ  . ARG A 1 592 ? -16.136 6.043   67.154  1.00 132.47 ? 667  ARG A CZ  1 
ATOM   4575  N NH1 . ARG A 1 592 ? -17.022 6.690   66.412  1.00 133.91 ? 667  ARG A NH1 1 
ATOM   4576  N NH2 . ARG A 1 592 ? -15.600 4.917   66.692  1.00 135.57 ? 667  ARG A NH2 1 
ATOM   4577  N N   . LEU A 1 593 ? -13.812 11.436  66.328  1.00 95.06  ? 668  LEU A N   1 
ATOM   4578  C CA  . LEU A 1 593 ? -13.662 12.657  65.549  1.00 86.26  ? 668  LEU A CA  1 
ATOM   4579  C C   . LEU A 1 593 ? -14.110 12.423  64.116  1.00 89.52  ? 668  LEU A C   1 
ATOM   4580  O O   . LEU A 1 593 ? -14.955 13.156  63.586  1.00 98.49  ? 668  LEU A O   1 
ATOM   4581  C CB  . LEU A 1 593 ? -12.207 13.127  65.598  1.00 93.30  ? 668  LEU A CB  1 
ATOM   4582  C CG  . LEU A 1 593 ? -11.790 13.920  66.838  1.00 81.14  ? 668  LEU A CG  1 
ATOM   4583  C CD1 . LEU A 1 593 ? -10.289 14.168  66.854  1.00 84.09  ? 668  LEU A CD1 1 
ATOM   4584  C CD2 . LEU A 1 593 ? -12.550 15.231  66.906  1.00 91.42  ? 668  LEU A CD2 1 
ATOM   4585  N N   . LEU A 1 594 ? -13.609 11.347  63.501  1.00 101.55 ? 669  LEU A N   1 
ATOM   4586  C CA  . LEU A 1 594 ? -13.917 11.103  62.098  1.00 107.79 ? 669  LEU A CA  1 
ATOM   4587  C C   . LEU A 1 594 ? -15.404 10.872  61.901  1.00 106.97 ? 669  LEU A C   1 
ATOM   4588  O O   . LEU A 1 594 ? -15.983 11.342  60.912  1.00 103.72 ? 669  LEU A O   1 
ATOM   4589  C CB  . LEU A 1 594 ? -13.107 9.917   61.571  1.00 100.84 ? 669  LEU A CB  1 
ATOM   4590  C CG  . LEU A 1 594 ? -11.737 10.320  61.009  1.00 74.99  ? 669  LEU A CG  1 
ATOM   4591  C CD1 . LEU A 1 594 ? -11.058 9.227   60.210  1.00 85.83  ? 669  LEU A CD1 1 
ATOM   4592  C CD2 . LEU A 1 594 ? -11.862 11.574  60.158  1.00 75.38  ? 669  LEU A CD2 1 
ATOM   4593  N N   . GLU A 1 595 ? -16.044 10.175  62.846  1.00 107.17 ? 670  GLU A N   1 
ATOM   4594  C CA  . GLU A 1 595 ? -17.478 9.946   62.732  1.00 109.37 ? 670  GLU A CA  1 
ATOM   4595  C C   . GLU A 1 595 ? -18.216 11.268  62.593  1.00 109.93 ? 670  GLU A C   1 
ATOM   4596  O O   . GLU A 1 595 ? -19.156 11.386  61.800  1.00 115.44 ? 670  GLU A O   1 
ATOM   4597  C CB  . GLU A 1 595 ? -17.993 9.167   63.943  1.00 83.93  ? 670  GLU A CB  1 
ATOM   4598  C CG  . GLU A 1 595 ? -19.495 9.287   64.162  1.00 137.29 ? 670  GLU A CG  1 
ATOM   4599  C CD  . GLU A 1 595 ? -19.860 10.374  65.155  1.00 146.59 ? 670  GLU A CD  1 
ATOM   4600  O OE1 . GLU A 1 595 ? -18.954 10.859  65.863  1.00 164.47 ? 670  GLU A OE1 1 
ATOM   4601  O OE2 . GLU A 1 595 ? -21.054 10.741  65.225  1.00 114.71 ? 670  GLU A OE2 1 
ATOM   4602  N N   . ASP A 1 596 ? -17.779 12.289  63.332  1.00 119.04 ? 671  ASP A N   1 
ATOM   4603  C CA  . ASP A 1 596 ? -18.396 13.598  63.185  1.00 119.57 ? 671  ASP A CA  1 
ATOM   4604  C C   . ASP A 1 596 ? -17.852 14.344  61.975  1.00 122.45 ? 671  ASP A C   1 
ATOM   4605  O O   . ASP A 1 596 ? -18.588 15.108  61.342  1.00 130.19 ? 671  ASP A O   1 
ATOM   4606  C CB  . ASP A 1 596 ? -18.193 14.426  64.452  1.00 138.07 ? 671  ASP A CB  1 
ATOM   4607  C CG  . ASP A 1 596 ? -18.754 15.821  64.322  1.00 159.65 ? 671  ASP A CG  1 
ATOM   4608  O OD1 . ASP A 1 596 ? -19.981 15.940  64.135  1.00 201.85 ? 671  ASP A OD1 1 
ATOM   4609  O OD2 . ASP A 1 596 ? -17.975 16.796  64.403  1.00 158.74 ? 671  ASP A OD2 1 
ATOM   4610  N N   . PHE A 1 597 ? -16.583 14.122  61.631  1.00 114.63 ? 672  PHE A N   1 
ATOM   4611  C CA  . PHE A 1 597 ? -15.973 14.857  60.529  1.00 116.36 ? 672  PHE A CA  1 
ATOM   4612  C C   . PHE A 1 597 ? -16.561 14.414  59.196  1.00 110.71 ? 672  PHE A C   1 
ATOM   4613  O O   . PHE A 1 597 ? -16.893 15.244  58.341  1.00 99.60  ? 672  PHE A O   1 
ATOM   4614  C CB  . PHE A 1 597 ? -14.458 14.648  60.548  1.00 106.50 ? 672  PHE A CB  1 
ATOM   4615  C CG  . PHE A 1 597 ? -13.681 15.740  59.872  1.00 99.04  ? 672  PHE A CG  1 
ATOM   4616  C CD1 . PHE A 1 597 ? -13.824 17.057  60.275  1.00 109.50 ? 672  PHE A CD1 1 
ATOM   4617  C CD2 . PHE A 1 597 ? -12.802 15.451  58.842  1.00 92.45  ? 672  PHE A CD2 1 
ATOM   4618  C CE1 . PHE A 1 597 ? -13.105 18.064  59.665  1.00 104.79 ? 672  PHE A CE1 1 
ATOM   4619  C CE2 . PHE A 1 597 ? -12.082 16.459  58.225  1.00 102.44 ? 672  PHE A CE2 1 
ATOM   4620  C CZ  . PHE A 1 597 ? -12.237 17.767  58.638  1.00 106.31 ? 672  PHE A CZ  1 
ATOM   4621  N N   . LEU A 1 598 ? -16.701 13.103  59.008  1.00 110.59 ? 673  LEU A N   1 
ATOM   4622  C CA  . LEU A 1 598 ? -17.265 12.539  57.783  1.00 123.41 ? 673  LEU A CA  1 
ATOM   4623  C C   . LEU A 1 598 ? -18.758 12.277  57.987  1.00 127.88 ? 673  LEU A C   1 
ATOM   4624  O O   . LEU A 1 598 ? -19.231 11.140  58.035  1.00 134.32 ? 673  LEU A O   1 
ATOM   4625  C CB  . LEU A 1 598 ? -16.521 11.268  57.396  1.00 122.37 ? 673  LEU A CB  1 
ATOM   4626  C CG  . LEU A 1 598 ? -15.002 11.378  57.260  1.00 104.76 ? 673  LEU A CG  1 
ATOM   4627  C CD1 . LEU A 1 598 ? -14.428 10.061  56.785  1.00 105.99 ? 673  LEU A CD1 1 
ATOM   4628  C CD2 . LEU A 1 598 ? -14.628 12.499  56.305  1.00 78.61  ? 673  LEU A CD2 1 
ATOM   4629  N N   . GLN A 1 599 ? -19.505 13.369  58.107  1.00 129.00 ? 674  GLN A N   1 
ATOM   4630  C CA  . GLN A 1 599 ? -20.943 13.307  58.302  1.00 135.57 ? 674  GLN A CA  1 
ATOM   4631  C C   . GLN A 1 599 ? -21.647 13.979  57.131  1.00 138.36 ? 674  GLN A C   1 
ATOM   4632  O O   . GLN A 1 599 ? -21.120 14.918  56.526  1.00 131.63 ? 674  GLN A O   1 
ATOM   4633  C CB  . GLN A 1 599 ? -21.357 13.967  59.623  1.00 142.78 ? 674  GLN A CB  1 
ATOM   4634  C CG  . GLN A 1 599 ? -22.659 13.430  60.196  1.00 146.24 ? 674  GLN A CG  1 
ATOM   4635  C CD  . GLN A 1 599 ? -22.560 11.968  60.591  1.00 159.11 ? 674  GLN A CD  1 
ATOM   4636  O OE1 . GLN A 1 599 ? -21.897 11.620  61.568  1.00 161.67 ? 674  GLN A OE1 1 
ATOM   4637  N NE2 . GLN A 1 599 ? -23.214 11.102  59.825  1.00 166.81 ? 674  GLN A NE2 1 
ATOM   4638  N N   . GLU A 1 600 ? -22.850 13.487  56.821  1.00 140.92 ? 675  GLU A N   1 
ATOM   4639  C CA  . GLU A 1 600 ? -23.580 13.976  55.654  1.00 135.38 ? 675  GLU A CA  1 
ATOM   4640  C C   . GLU A 1 600 ? -23.882 15.468  55.767  1.00 128.98 ? 675  GLU A C   1 
ATOM   4641  O O   . GLU A 1 600 ? -23.870 16.187  54.762  1.00 122.42 ? 675  GLU A O   1 
ATOM   4642  C CB  . GLU A 1 600 ? -24.867 13.168  55.460  1.00 144.73 ? 675  GLU A CB  1 
ATOM   4643  C CG  . GLU A 1 600 ? -26.045 13.592  56.338  1.00 167.53 ? 675  GLU A CG  1 
ATOM   4644  C CD  . GLU A 1 600 ? -25.793 13.380  57.818  1.00 175.62 ? 675  GLU A CD  1 
ATOM   4645  O OE1 . GLU A 1 600 ? -26.342 14.153  58.633  1.00 207.98 ? 675  GLU A OE1 1 
ATOM   4646  O OE2 . GLU A 1 600 ? -25.052 12.438  58.167  1.00 175.36 ? 675  GLU A OE2 1 
ATOM   4647  N N   . GLY A 1 601 ? -24.143 15.956  56.977  1.00 131.85 ? 676  GLY A N   1 
ATOM   4648  C CA  . GLY A 1 601 ? -24.379 17.372  57.171  1.00 134.50 ? 676  GLY A CA  1 
ATOM   4649  C C   . GLY A 1 601 ? -23.596 17.927  58.340  1.00 146.69 ? 676  GLY A C   1 
ATOM   4650  O O   . GLY A 1 601 ? -24.130 18.070  59.444  1.00 152.11 ? 676  GLY A O   1 
ATOM   4651  N N   . GLU A 1 602 ? -22.319 18.260  58.105  1.00 138.04 ? 677  GLU A N   1 
ATOM   4652  C CA  . GLU A 1 602 ? -21.415 18.695  59.169  1.00 147.81 ? 677  GLU A CA  1 
ATOM   4653  C C   . GLU A 1 602 ? -20.322 19.536  58.506  1.00 148.05 ? 677  GLU A C   1 
ATOM   4654  O O   . GLU A 1 602 ? -19.221 19.061  58.217  1.00 171.09 ? 677  GLU A O   1 
ATOM   4655  C CB  . GLU A 1 602 ? -20.828 17.513  59.943  1.00 148.91 ? 677  GLU A CB  1 
ATOM   4656  C CG  . GLU A 1 602 ? -20.526 17.810  61.398  1.00 158.62 ? 677  GLU A CG  1 
ATOM   4657  C CD  . GLU A 1 602 ? -21.777 17.758  62.270  1.00 177.42 ? 677  GLU A CD  1 
ATOM   4658  O OE1 . GLU A 1 602 ? -22.610 16.850  62.062  1.00 186.13 ? 677  GLU A OE1 1 
ATOM   4659  O OE2 . GLU A 1 602 ? -21.949 18.643  63.138  1.00 175.62 ? 677  GLU A OE2 1 
ATOM   4660  N N   . GLU A 1 603 ? -20.651 20.801  58.251  1.00 142.55 ? 678  GLU A N   1 
ATOM   4661  C CA  . GLU A 1 603 ? -19.670 21.764  57.777  1.00 145.09 ? 678  GLU A CA  1 
ATOM   4662  C C   . GLU A 1 603 ? -18.521 21.836  58.772  1.00 147.98 ? 678  GLU A C   1 
ATOM   4663  O O   . GLU A 1 603 ? -18.731 22.255  59.919  1.00 150.33 ? 678  GLU A O   1 
ATOM   4664  C CB  . GLU A 1 603 ? -20.298 23.144  57.597  1.00 132.89 ? 678  GLU A CB  1 
ATOM   4665  C CG  . GLU A 1 603 ? -20.906 23.405  56.222  1.00 129.90 ? 678  GLU A CG  1 
ATOM   4666  C CD  . GLU A 1 603 ? -22.123 22.551  55.903  1.00 140.28 ? 678  GLU A CD  1 
ATOM   4667  O OE1 . GLU A 1 603 ? -22.670 22.712  54.791  1.00 137.35 ? 678  GLU A OE1 1 
ATOM   4668  O OE2 . GLU A 1 603 ? -22.557 21.751  56.758  1.00 143.71 ? 678  GLU A OE2 1 
ATOM   4669  N N   . PRO A 1 604 ? -17.310 21.436  58.390  1.00 139.53 ? 679  PRO A N   1 
ATOM   4670  C CA  . PRO A 1 604 ? -16.206 21.394  59.356  1.00 144.86 ? 679  PRO A CA  1 
ATOM   4671  C C   . PRO A 1 604 ? -15.733 22.794  59.717  1.00 146.88 ? 679  PRO A C   1 
ATOM   4672  O O   . PRO A 1 604 ? -15.395 23.597  58.845  1.00 148.07 ? 679  PRO A O   1 
ATOM   4673  C CB  . PRO A 1 604 ? -15.123 20.606  58.614  1.00 150.34 ? 679  PRO A CB  1 
ATOM   4674  C CG  . PRO A 1 604 ? -15.401 20.869  57.168  1.00 141.00 ? 679  PRO A CG  1 
ATOM   4675  C CD  . PRO A 1 604 ? -16.893 21.011  57.042  1.00 132.04 ? 679  PRO A CD  1 
ATOM   4676  N N   . ASP A 1 605 ? -15.720 23.083  61.015  1.00 141.52 ? 680  ASP A N   1 
ATOM   4677  C CA  . ASP A 1 605 ? -15.090 24.301  61.493  1.00 145.70 ? 680  ASP A CA  1 
ATOM   4678  C C   . ASP A 1 605 ? -13.582 24.091  61.590  1.00 155.43 ? 680  ASP A C   1 
ATOM   4679  O O   . ASP A 1 605 ? -13.086 22.960  61.600  1.00 157.01 ? 680  ASP A O   1 
ATOM   4680  C CB  . ASP A 1 605 ? -15.664 24.713  62.850  1.00 130.41 ? 680  ASP A CB  1 
ATOM   4681  C CG  . ASP A 1 605 ? -15.895 23.530  63.771  1.00 138.73 ? 680  ASP A CG  1 
ATOM   4682  O OD1 . ASP A 1 605 ? -16.866 22.777  63.547  1.00 142.23 ? 680  ASP A OD1 1 
ATOM   4683  O OD2 . ASP A 1 605 ? -15.111 23.360  64.728  1.00 147.79 ? 680  ASP A OD2 1 
ATOM   4684  N N   . GLU A 1 606 ? -12.846 25.204  61.656  1.00 154.03 ? 681  GLU A N   1 
ATOM   4685  C CA  . GLU A 1 606 ? -11.391 25.112  61.716  1.00 141.25 ? 681  GLU A CA  1 
ATOM   4686  C C   . GLU A 1 606 ? -10.925 24.350  62.953  1.00 143.53 ? 681  GLU A C   1 
ATOM   4687  O O   . GLU A 1 606 ? -9.908  23.648  62.902  1.00 150.64 ? 681  GLU A O   1 
ATOM   4688  C CB  . GLU A 1 606 ? -10.770 26.511  61.661  1.00 151.62 ? 681  GLU A CB  1 
ATOM   4689  C CG  . GLU A 1 606 ? -11.584 27.618  62.322  1.00 176.51 ? 681  GLU A CG  1 
ATOM   4690  C CD  . GLU A 1 606 ? -11.350 27.708  63.816  1.00 204.04 ? 681  GLU A CD  1 
ATOM   4691  O OE1 . GLU A 1 606 ? -10.351 27.134  64.299  1.00 235.50 ? 681  GLU A OE1 1 
ATOM   4692  O OE2 . GLU A 1 606 ? -12.155 28.371  64.505  1.00 230.35 ? 681  GLU A OE2 1 
ATOM   4693  N N   . ASP A 1 607 ? -11.665 24.451  64.061  1.00 150.08 ? 682  ASP A N   1 
ATOM   4694  C CA  . ASP A 1 607 ? -11.322 23.674  65.250  1.00 150.98 ? 682  ASP A CA  1 
ATOM   4695  C C   . ASP A 1 607 ? -11.517 22.181  65.012  1.00 136.37 ? 682  ASP A C   1 
ATOM   4696  O O   . ASP A 1 607 ? -10.712 21.364  65.471  1.00 166.91 ? 682  ASP A O   1 
ATOM   4697  C CB  . ASP A 1 607 ? -12.151 24.132  66.450  1.00 159.07 ? 682  ASP A CB  1 
ATOM   4698  C CG  . ASP A 1 607 ? -12.043 25.621  66.701  1.00 188.71 ? 682  ASP A CG  1 
ATOM   4699  O OD1 . ASP A 1 607 ? -12.935 26.367  66.250  1.00 201.75 ? 682  ASP A OD1 1 
ATOM   4700  O OD2 . ASP A 1 607 ? -11.065 26.041  67.355  1.00 210.31 ? 682  ASP A OD2 1 
ATOM   4701  N N   . ASP A 1 608 ? -12.583 21.806  64.304  1.00 129.15 ? 683  ASP A N   1 
ATOM   4702  C CA  . ASP A 1 608 ? -12.824 20.396  64.013  1.00 131.43 ? 683  ASP A CA  1 
ATOM   4703  C C   . ASP A 1 608 ? -11.692 19.816  63.170  1.00 123.20 ? 683  ASP A C   1 
ATOM   4704  O O   . ASP A 1 608 ? -11.156 18.734  63.467  1.00 111.13 ? 683  ASP A O   1 
ATOM   4705  C CB  . ASP A 1 608 ? -14.167 20.249  63.295  1.00 140.67 ? 683  ASP A CB  1 
ATOM   4706  C CG  . ASP A 1 608 ? -15.305 19.935  64.244  1.00 136.64 ? 683  ASP A CG  1 
ATOM   4707  O OD1 . ASP A 1 608 ? -15.098 20.025  65.472  1.00 134.62 ? 683  ASP A OD1 1 
ATOM   4708  O OD2 . ASP A 1 608 ? -16.413 19.617  63.761  1.00 130.85 ? 683  ASP A OD2 1 
ATOM   4709  N N   . ALA A 1 609 ? -11.322 20.534  62.105  1.00 129.49 ? 684  ALA A N   1 
ATOM   4710  C CA  . ALA A 1 609 ? -10.218 20.108  61.256  1.00 118.53 ? 684  ALA A CA  1 
ATOM   4711  C C   . ALA A 1 609 ? -8.920  20.030  62.045  1.00 109.09 ? 684  ALA A C   1 
ATOM   4712  O O   . ALA A 1 609 ? -8.135  19.095  61.864  1.00 104.63 ? 684  ALA A O   1 
ATOM   4713  C CB  . ALA A 1 609 ? -10.071 21.057  60.067  1.00 102.31 ? 684  ALA A CB  1 
ATOM   4714  N N   . TYR A 1 610 ? -8.684  20.994  62.940  1.00 108.88 ? 685  TYR A N   1 
ATOM   4715  C CA  . TYR A 1 610 ? -7.481  20.956  63.767  1.00 102.63 ? 685  TYR A CA  1 
ATOM   4716  C C   . TYR A 1 610 ? -7.466  19.738  64.683  1.00 103.96 ? 685  TYR A C   1 
ATOM   4717  O O   . TYR A 1 610 ? -6.418  19.114  64.878  1.00 114.89 ? 685  TYR A O   1 
ATOM   4718  C CB  . TYR A 1 610 ? -7.364  22.237  64.589  1.00 104.87 ? 685  TYR A CB  1 
ATOM   4719  C CG  . TYR A 1 610 ? -5.998  22.435  65.201  1.00 110.61 ? 685  TYR A CG  1 
ATOM   4720  C CD1 . TYR A 1 610 ? -4.845  22.275  64.442  1.00 120.53 ? 685  TYR A CD1 1 
ATOM   4721  C CD2 . TYR A 1 610 ? -5.860  22.769  66.541  1.00 110.85 ? 685  TYR A CD2 1 
ATOM   4722  C CE1 . TYR A 1 610 ? -3.592  22.452  65.000  1.00 121.80 ? 685  TYR A CE1 1 
ATOM   4723  C CE2 . TYR A 1 610 ? -4.614  22.947  67.108  1.00 119.07 ? 685  TYR A CE2 1 
ATOM   4724  C CZ  . TYR A 1 610 ? -3.484  22.788  66.334  1.00 124.30 ? 685  TYR A CZ  1 
ATOM   4725  O OH  . TYR A 1 610 ? -2.242  22.965  66.899  1.00 118.40 ? 685  TYR A OH  1 
ATOM   4726  N N   . GLN A 1 611 ? -8.618  19.394  65.262  1.00 100.32 ? 686  GLN A N   1 
ATOM   4727  C CA  . GLN A 1 611 ? -8.701  18.225  66.132  1.00 95.16  ? 686  GLN A CA  1 
ATOM   4728  C C   . GLN A 1 611 ? -8.332  16.955  65.372  1.00 93.35  ? 686  GLN A C   1 
ATOM   4729  O O   . GLN A 1 611 ? -7.440  16.192  65.789  1.00 91.31  ? 686  GLN A O   1 
ATOM   4730  C CB  . GLN A 1 611 ? -10.114 18.105  66.708  1.00 103.99 ? 686  GLN A CB  1 
ATOM   4731  C CG  . GLN A 1 611 ? -10.266 18.562  68.152  1.00 100.29 ? 686  GLN A CG  1 
ATOM   4732  C CD  . GLN A 1 611 ? -9.745  19.968  68.383  1.00 110.54 ? 686  GLN A CD  1 
ATOM   4733  O OE1 . GLN A 1 611 ? -10.436 20.950  68.113  1.00 124.52 ? 686  GLN A OE1 1 
ATOM   4734  N NE2 . GLN A 1 611 ? -8.519  20.072  68.882  1.00 110.48 ? 686  GLN A NE2 1 
ATOM   4735  N N   . VAL A 1 612 ? -9.025  16.709  64.254  1.00 97.74  ? 687  VAL A N   1 
ATOM   4736  C CA  . VAL A 1 612 ? -8.765  15.487  63.494  1.00 101.03 ? 687  VAL A CA  1 
ATOM   4737  C C   . VAL A 1 612 ? -7.332  15.487  62.975  1.00 100.52 ? 687  VAL A C   1 
ATOM   4738  O O   . VAL A 1 612 ? -6.668  14.444  62.949  1.00 106.13 ? 687  VAL A O   1 
ATOM   4739  C CB  . VAL A 1 612 ? -9.794  15.309  62.358  1.00 95.28  ? 687  VAL A CB  1 
ATOM   4740  C CG1 . VAL A 1 612 ? -9.846  16.527  61.464  1.00 89.24  ? 687  VAL A CG1 1 
ATOM   4741  C CG2 . VAL A 1 612 ? -9.490  14.055  61.541  1.00 92.86  ? 687  VAL A CG2 1 
ATOM   4742  N N   . LEU A 1 613 ? -6.810  16.664  62.616  1.00 95.19  ? 688  LEU A N   1 
ATOM   4743  C CA  . LEU A 1 613 ? -5.446  16.757  62.111  1.00 85.57  ? 688  LEU A CA  1 
ATOM   4744  C C   . LEU A 1 613 ? -4.428  16.407  63.188  1.00 81.22  ? 688  LEU A C   1 
ATOM   4745  O O   . LEU A 1 613 ? -3.471  15.674  62.928  1.00 86.32  ? 688  LEU A O   1 
ATOM   4746  C CB  . LEU A 1 613 ? -5.188  18.161  61.562  1.00 79.50  ? 688  LEU A CB  1 
ATOM   4747  C CG  . LEU A 1 613 ? -3.800  18.418  60.969  1.00 68.33  ? 688  LEU A CG  1 
ATOM   4748  C CD1 . LEU A 1 613 ? -3.434  17.366  59.934  1.00 79.40  ? 688  LEU A CD1 1 
ATOM   4749  C CD2 . LEU A 1 613 ? -3.724  19.814  60.373  1.00 65.52  ? 688  LEU A CD2 1 
ATOM   4750  N N   . SER A 1 614 ? -4.606  16.932  64.402  1.00 74.06  ? 689  SER A N   1 
ATOM   4751  C CA  . SER A 1 614 ? -3.656  16.653  65.474  1.00 76.50  ? 689  SER A CA  1 
ATOM   4752  C C   . SER A 1 614 ? -3.643  15.169  65.821  1.00 77.68  ? 689  SER A C   1 
ATOM   4753  O O   . SER A 1 614 ? -2.572  14.550  65.940  1.00 86.20  ? 689  SER A O   1 
ATOM   4754  C CB  . SER A 1 614 ? -3.996  17.492  66.706  1.00 72.16  ? 689  SER A CB  1 
ATOM   4755  O OG  . SER A 1 614 ? -4.166  18.857  66.366  1.00 79.94  ? 689  SER A OG  1 
ATOM   4756  N N   . THR A 1 615 ? -4.829  14.575  65.991  1.00 74.87  ? 690  THR A N   1 
ATOM   4757  C CA  . THR A 1 615 ? -4.865  13.150  66.312  1.00 80.98  ? 690  THR A CA  1 
ATOM   4758  C C   . THR A 1 615 ? -4.287  12.313  65.172  1.00 72.63  ? 690  THR A C   1 
ATOM   4759  O O   . THR A 1 615 ? -3.577  11.326  65.411  1.00 64.09  ? 690  THR A O   1 
ATOM   4760  C CB  . THR A 1 615 ? -6.290  12.712  66.649  1.00 74.12  ? 690  THR A CB  1 
ATOM   4761  O OG1 . THR A 1 615 ? -7.204  13.277  65.703  1.00 81.28  ? 690  THR A OG1 1 
ATOM   4762  C CG2 . THR A 1 615 ? -6.664  13.170  68.052  1.00 85.10  ? 690  THR A CG2 1 
ATOM   4763  N N   . LEU A 1 616 ? -4.557  12.710  63.923  1.00 73.41  ? 691  LEU A N   1 
ATOM   4764  C CA  . LEU A 1 616 ? -3.995  12.009  62.774  1.00 74.71  ? 691  LEU A CA  1 
ATOM   4765  C C   . LEU A 1 616 ? -2.477  12.111  62.748  1.00 86.70  ? 691  LEU A C   1 
ATOM   4766  O O   . LEU A 1 616 ? -1.791  11.150  62.389  1.00 89.98  ? 691  LEU A O   1 
ATOM   4767  C CB  . LEU A 1 616 ? -4.592  12.577  61.487  1.00 61.84  ? 691  LEU A CB  1 
ATOM   4768  C CG  . LEU A 1 616 ? -3.971  12.135  60.162  1.00 67.88  ? 691  LEU A CG  1 
ATOM   4769  C CD1 . LEU A 1 616 ? -4.183  10.647  59.933  1.00 63.11  ? 691  LEU A CD1 1 
ATOM   4770  C CD2 . LEU A 1 616 ? -4.546  12.950  59.014  1.00 68.23  ? 691  LEU A CD2 1 
ATOM   4771  N N   . LYS A 1 617 ? -1.936  13.273  63.119  1.00 83.63  ? 692  LYS A N   1 
ATOM   4772  C CA  . LYS A 1 617 ? -0.488  13.452  63.142  1.00 68.79  ? 692  LYS A CA  1 
ATOM   4773  C C   . LYS A 1 617 ? 0.153   12.548  64.184  1.00 70.45  ? 692  LYS A C   1 
ATOM   4774  O O   . LYS A 1 617 ? 1.170   11.896  63.912  1.00 84.62  ? 692  LYS A O   1 
ATOM   4775  C CB  . LYS A 1 617 ? -0.165  14.923  63.406  1.00 53.42  ? 692  LYS A CB  1 
ATOM   4776  C CG  . LYS A 1 617 ? -0.520  15.833  62.237  1.00 64.30  ? 692  LYS A CG  1 
ATOM   4777  C CD  . LYS A 1 617 ? -0.211  17.296  62.511  1.00 58.86  ? 692  LYS A CD  1 
ATOM   4778  C CE  . LYS A 1 617 ? 1.272   17.556  62.659  1.00 78.13  ? 692  LYS A CE  1 
ATOM   4779  N NZ  . LYS A 1 617 ? 1.558   19.019  62.698  1.00 84.60  ? 692  LYS A NZ  1 
ATOM   4780  N N   . ARG A 1 618 ? -0.440  12.484  65.378  1.00 63.60  ? 693  ARG A N   1 
ATOM   4781  C CA  . ARG A 1 618 ? 0.061   11.565  66.398  1.00 64.82  ? 693  ARG A CA  1 
ATOM   4782  C C   . ARG A 1 618 ? 0.027   10.119  65.906  1.00 64.41  ? 693  ARG A C   1 
ATOM   4783  O O   . ARG A 1 618 ? 1.018   9.379   66.027  1.00 65.76  ? 693  ARG A O   1 
ATOM   4784  C CB  . ARG A 1 618 ? -0.754  11.726  67.681  1.00 74.13  ? 693  ARG A CB  1 
ATOM   4785  C CG  . ARG A 1 618 ? -0.429  13.001  68.439  1.00 78.25  ? 693  ARG A CG  1 
ATOM   4786  C CD  . ARG A 1 618 ? -1.682  13.666  68.972  1.00 73.54  ? 693  ARG A CD  1 
ATOM   4787  N NE  . ARG A 1 618 ? -1.485  15.100  69.141  1.00 75.04  ? 693  ARG A NE  1 
ATOM   4788  C CZ  . ARG A 1 618 ? -2.325  15.903  69.778  1.00 80.54  ? 693  ARG A CZ  1 
ATOM   4789  N NH1 . ARG A 1 618 ? -3.457  15.451  70.292  1.00 89.50  ? 693  ARG A NH1 1 
ATOM   4790  N NH2 . ARG A 1 618 ? -2.024  17.194  69.896  1.00 85.96  ? 693  ARG A NH2 1 
ATOM   4791  N N   . ILE A 1 619 ? -1.106  9.704   65.331  1.00 60.24  ? 694  ILE A N   1 
ATOM   4792  C CA  . ILE A 1 619 ? -1.249  8.314   64.906  1.00 72.42  ? 694  ILE A CA  1 
ATOM   4793  C C   . ILE A 1 619 ? -0.284  7.992   63.770  1.00 73.17  ? 694  ILE A C   1 
ATOM   4794  O O   . ILE A 1 619 ? 0.272   6.893   63.709  1.00 69.91  ? 694  ILE A O   1 
ATOM   4795  C CB  . ILE A 1 619 ? -2.708  8.017   64.520  1.00 72.29  ? 694  ILE A CB  1 
ATOM   4796  C CG1 . ILE A 1 619 ? -3.606  8.136   65.750  1.00 79.30  ? 694  ILE A CG1 1 
ATOM   4797  C CG2 . ILE A 1 619 ? -2.829  6.631   63.897  1.00 73.94  ? 694  ILE A CG2 1 
ATOM   4798  C CD1 . ILE A 1 619 ? -5.068  7.924   65.458  1.00 104.99 ? 694  ILE A CD1 1 
ATOM   4799  N N   . THR A 1 620 ? -0.057  8.946   62.865  1.00 69.58  ? 695  THR A N   1 
ATOM   4800  C CA  . THR A 1 620 ? 0.886   8.735   61.771  1.00 64.15  ? 695  THR A CA  1 
ATOM   4801  C C   . THR A 1 620 ? 2.307   8.589   62.297  1.00 71.40  ? 695  THR A C   1 
ATOM   4802  O O   . THR A 1 620 ? 3.055   7.690   61.879  1.00 79.61  ? 695  THR A O   1 
ATOM   4803  C CB  . THR A 1 620 ? 0.803   9.904   60.788  1.00 66.32  ? 695  THR A CB  1 
ATOM   4804  O OG1 . THR A 1 620 ? -0.554  10.082  60.362  1.00 73.91  ? 695  THR A OG1 1 
ATOM   4805  C CG2 . THR A 1 620 ? 1.689   9.653   59.580  1.00 67.69  ? 695  THR A CG2 1 
ATOM   4806  N N   . ALA A 1 621 ? 2.701   9.483   63.208  1.00 61.79  ? 696  ALA A N   1 
ATOM   4807  C CA  . ALA A 1 621 ? 4.030   9.405   63.800  1.00 61.16  ? 696  ALA A CA  1 
ATOM   4808  C C   . ALA A 1 621 ? 4.261   8.044   64.442  1.00 63.83  ? 696  ALA A C   1 
ATOM   4809  O O   . ALA A 1 621 ? 5.309   7.421   64.241  1.00 76.94  ? 696  ALA A O   1 
ATOM   4810  C CB  . ALA A 1 621 ? 4.216   10.526  64.821  1.00 59.95  ? 696  ALA A CB  1 
ATOM   4811  N N   . PHE A 1 622 ? 3.283   7.552   65.207  1.00 51.21  ? 697  PHE A N   1 
ATOM   4812  C CA  . PHE A 1 622 ? 3.498   6.263   65.860  1.00 60.26  ? 697  PHE A CA  1 
ATOM   4813  C C   . PHE A 1 622 ? 3.371   5.091   64.891  1.00 64.91  ? 697  PHE A C   1 
ATOM   4814  O O   . PHE A 1 622 ? 4.029   4.063   65.085  1.00 64.16  ? 697  PHE A O   1 
ATOM   4815  C CB  . PHE A 1 622 ? 2.549   6.095   67.043  1.00 64.07  ? 697  PHE A CB  1 
ATOM   4816  C CG  . PHE A 1 622 ? 3.031   6.772   68.291  1.00 60.84  ? 697  PHE A CG  1 
ATOM   4817  C CD1 . PHE A 1 622 ? 2.884   8.139   68.455  1.00 54.53  ? 697  PHE A CD1 1 
ATOM   4818  C CD2 . PHE A 1 622 ? 3.661   6.044   69.288  1.00 58.76  ? 697  PHE A CD2 1 
ATOM   4819  C CE1 . PHE A 1 622 ? 3.339   8.764   69.600  1.00 50.71  ? 697  PHE A CE1 1 
ATOM   4820  C CE2 . PHE A 1 622 ? 4.119   6.664   70.437  1.00 64.08  ? 697  PHE A CE2 1 
ATOM   4821  C CZ  . PHE A 1 622 ? 3.958   8.026   70.592  1.00 63.64  ? 697  PHE A CZ  1 
ATOM   4822  N N   . HIS A 1 623 ? 2.557   5.223   63.842  1.00 67.65  ? 698  HIS A N   1 
ATOM   4823  C CA  . HIS A 1 623 ? 2.399   4.135   62.885  1.00 76.06  ? 698  HIS A CA  1 
ATOM   4824  C C   . HIS A 1 623 ? 3.637   3.964   62.018  1.00 78.70  ? 698  HIS A C   1 
ATOM   4825  O O   . HIS A 1 623 ? 3.885   2.866   61.505  1.00 78.95  ? 698  HIS A O   1 
ATOM   4826  C CB  . HIS A 1 623 ? 1.172   4.386   62.009  1.00 71.24  ? 698  HIS A CB  1 
ATOM   4827  C CG  . HIS A 1 623 ? 0.445   3.140   61.616  1.00 76.08  ? 698  HIS A CG  1 
ATOM   4828  N ND1 . HIS A 1 623 ? 1.080   1.926   61.459  1.00 81.58  ? 698  HIS A ND1 1 
ATOM   4829  C CD2 . HIS A 1 623 ? -0.863  2.919   61.347  1.00 75.77  ? 698  HIS A CD2 1 
ATOM   4830  C CE1 . HIS A 1 623 ? 0.193   1.010   61.112  1.00 81.99  ? 698  HIS A CE1 1 
ATOM   4831  N NE2 . HIS A 1 623 ? -0.993  1.586   61.039  1.00 78.27  ? 698  HIS A NE2 1 
ATOM   4832  N N   . ASN A 1 624 ? 4.414   5.033   61.829  1.00 67.19  ? 699  ASN A N   1 
ATOM   4833  C CA  . ASN A 1 624 ? 5.665   4.894   61.088  1.00 66.16  ? 699  ASN A CA  1 
ATOM   4834  C C   . ASN A 1 624 ? 6.628   3.942   61.792  1.00 73.06  ? 699  ASN A C   1 
ATOM   4835  O O   . ASN A 1 624 ? 7.292   3.127   61.141  1.00 73.36  ? 699  ASN A O   1 
ATOM   4836  C CB  . ASN A 1 624 ? 6.320   6.259   60.885  1.00 68.46  ? 699  ASN A CB  1 
ATOM   4837  C CG  . ASN A 1 624 ? 7.315   6.263   59.739  1.00 73.91  ? 699  ASN A CG  1 
ATOM   4838  O OD1 . ASN A 1 624 ? 7.605   5.219   59.153  1.00 75.99  ? 699  ASN A OD1 1 
ATOM   4839  N ND2 . ASN A 1 624 ? 7.852   7.436   59.420  1.00 66.08  ? 699  ASN A ND2 1 
ATOM   4840  N N   . ALA A 1 625 ? 6.714   4.021   63.121  1.00 74.72  ? 700  ALA A N   1 
ATOM   4841  C CA  . ALA A 1 625 ? 7.689   3.249   63.881  1.00 67.53  ? 700  ALA A CA  1 
ATOM   4842  C C   . ALA A 1 625 ? 7.088   2.077   64.646  1.00 76.05  ? 700  ALA A C   1 
ATOM   4843  O O   . ALA A 1 625 ? 7.838   1.317   65.270  1.00 79.87  ? 700  ALA A O   1 
ATOM   4844  C CB  . ALA A 1 625 ? 8.436   4.164   64.860  1.00 67.86  ? 700  ALA A CB  1 
ATOM   4845  N N   . HIS A 1 626 ? 5.768   1.904   64.623  1.00 79.07  ? 701  HIS A N   1 
ATOM   4846  C CA  . HIS A 1 626 ? 5.121   0.870   65.417  1.00 78.28  ? 701  HIS A CA  1 
ATOM   4847  C C   . HIS A 1 626 ? 4.028   0.204   64.596  1.00 80.73  ? 701  HIS A C   1 
ATOM   4848  O O   . HIS A 1 626 ? 3.375   0.844   63.767  1.00 75.75  ? 701  HIS A O   1 
ATOM   4849  C CB  . HIS A 1 626 ? 4.534   1.451   66.709  1.00 66.57  ? 701  HIS A CB  1 
ATOM   4850  C CG  . HIS A 1 626 ? 5.522   2.226   67.524  1.00 69.28  ? 701  HIS A CG  1 
ATOM   4851  N ND1 . HIS A 1 626 ? 5.482   3.599   67.630  1.00 76.07  ? 701  HIS A ND1 1 
ATOM   4852  C CD2 . HIS A 1 626 ? 6.577   1.822   68.270  1.00 66.52  ? 701  HIS A CD2 1 
ATOM   4853  C CE1 . HIS A 1 626 ? 6.470   4.009   68.404  1.00 64.94  ? 701  HIS A CE1 1 
ATOM   4854  N NE2 . HIS A 1 626 ? 7.149   2.950   68.807  1.00 62.99  ? 701  HIS A NE2 1 
ATOM   4855  N N   . ASP A 1 627 ? 3.831   -1.090  64.836  1.00 81.83  ? 702  ASP A N   1 
ATOM   4856  C CA  . ASP A 1 627 ? 2.825   -1.868  64.116  1.00 74.93  ? 702  ASP A CA  1 
ATOM   4857  C C   . ASP A 1 627 ? 1.460   -1.596  64.736  1.00 78.80  ? 702  ASP A C   1 
ATOM   4858  O O   . ASP A 1 627 ? 1.091   -2.197  65.747  1.00 75.87  ? 702  ASP A O   1 
ATOM   4859  C CB  . ASP A 1 627 ? 3.167   -3.353  64.150  1.00 77.93  ? 702  ASP A CB  1 
ATOM   4860  C CG  . ASP A 1 627 ? 2.411   -4.149  63.103  1.00 86.24  ? 702  ASP A CG  1 
ATOM   4861  O OD1 . ASP A 1 627 ? 1.505   -3.581  62.460  1.00 102.20 ? 702  ASP A OD1 1 
ATOM   4862  O OD2 . ASP A 1 627 ? 2.727   -5.343  62.920  1.00 93.00  ? 702  ASP A OD2 1 
ATOM   4863  N N   . LEU A 1 628 ? 0.705   -0.684  64.125  1.00 88.54  ? 703  LEU A N   1 
ATOM   4864  C CA  . LEU A 1 628 ? -0.639  -0.349  64.575  1.00 84.75  ? 703  LEU A CA  1 
ATOM   4865  C C   . LEU A 1 628 ? -1.711  -1.071  63.770  1.00 88.40  ? 703  LEU A C   1 
ATOM   4866  O O   . LEU A 1 628 ? -2.875  -0.654  63.785  1.00 97.72  ? 703  LEU A O   1 
ATOM   4867  C CB  . LEU A 1 628 ? -0.863  1.162   64.507  1.00 81.01  ? 703  LEU A CB  1 
ATOM   4868  C CG  . LEU A 1 628 ? 0.192   2.047   65.170  1.00 77.71  ? 703  LEU A CG  1 
ATOM   4869  C CD1 . LEU A 1 628 ? -0.335  3.466   65.326  1.00 73.63  ? 703  LEU A CD1 1 
ATOM   4870  C CD2 . LEU A 1 628 ? 0.623   1.470   66.504  1.00 61.35  ? 703  LEU A CD2 1 
ATOM   4871  N N   . SER A 1 629 ? -1.340  -2.145  63.065  1.00 89.21  ? 704  SER A N   1 
ATOM   4872  C CA  . SER A 1 629 ? -2.296  -2.879  62.242  1.00 94.77  ? 704  SER A CA  1 
ATOM   4873  C C   . SER A 1 629 ? -3.430  -3.480  63.058  1.00 95.95  ? 704  SER A C   1 
ATOM   4874  O O   . SER A 1 629 ? -4.506  -3.732  62.506  1.00 104.27 ? 704  SER A O   1 
ATOM   4875  C CB  . SER A 1 629 ? -1.576  -3.985  61.468  1.00 97.66  ? 704  SER A CB  1 
ATOM   4876  O OG  . SER A 1 629 ? -0.774  -3.446  60.432  1.00 101.23 ? 704  SER A OG  1 
ATOM   4877  N N   . LYS A 1 630 ? -3.214  -3.721  64.353  1.00 90.07  ? 705  LYS A N   1 
ATOM   4878  C CA  . LYS A 1 630 ? -4.300  -4.196  65.203  1.00 90.57  ? 705  LYS A CA  1 
ATOM   4879  C C   . LYS A 1 630 ? -5.450  -3.197  65.231  1.00 87.13  ? 705  LYS A C   1 
ATOM   4880  O O   . LYS A 1 630 ? -6.623  -3.590  65.240  1.00 99.12  ? 705  LYS A O   1 
ATOM   4881  C CB  . LYS A 1 630 ? -3.775  -4.473  66.616  1.00 96.92  ? 705  LYS A CB  1 
ATOM   4882  C CG  . LYS A 1 630 ? -4.824  -4.863  67.667  1.00 100.98 ? 705  LYS A CG  1 
ATOM   4883  C CD  . LYS A 1 630 ? -5.436  -3.656  68.380  1.00 111.04 ? 705  LYS A CD  1 
ATOM   4884  C CE  . LYS A 1 630 ? -6.054  -4.051  69.709  1.00 124.34 ? 705  LYS A CE  1 
ATOM   4885  N NZ  . LYS A 1 630 ? -7.089  -3.076  70.145  1.00 145.38 ? 705  LYS A NZ  1 
ATOM   4886  N N   . TRP A 1 631 ? -5.137  -1.901  65.250  1.00 87.91  ? 706  TRP A N   1 
ATOM   4887  C CA  . TRP A 1 631 ? -6.178  -0.884  65.309  1.00 82.33  ? 706  TRP A CA  1 
ATOM   4888  C C   . TRP A 1 631 ? -6.870  -0.649  63.973  1.00 89.06  ? 706  TRP A C   1 
ATOM   4889  O O   . TRP A 1 631 ? -7.837  0.120   63.931  1.00 100.95 ? 706  TRP A O   1 
ATOM   4890  C CB  . TRP A 1 631 ? -5.610  0.437   65.838  1.00 77.63  ? 706  TRP A CB  1 
ATOM   4891  C CG  . TRP A 1 631 ? -5.297  0.400   67.302  1.00 83.85  ? 706  TRP A CG  1 
ATOM   4892  C CD1 . TRP A 1 631 ? -6.055  0.919   68.308  1.00 91.11  ? 706  TRP A CD1 1 
ATOM   4893  C CD2 . TRP A 1 631 ? -4.135  -0.165  67.926  1.00 92.02  ? 706  TRP A CD2 1 
ATOM   4894  N NE1 . TRP A 1 631 ? -5.450  0.701   69.521  1.00 87.72  ? 706  TRP A NE1 1 
ATOM   4895  C CE2 . TRP A 1 631 ? -4.269  0.038   69.314  1.00 91.96  ? 706  TRP A CE2 1 
ATOM   4896  C CE3 . TRP A 1 631 ? -3.000  -0.826  67.447  1.00 96.90  ? 706  TRP A CE3 1 
ATOM   4897  C CZ2 . TRP A 1 631 ? -3.310  -0.392  70.227  1.00 96.11  ? 706  TRP A CZ2 1 
ATOM   4898  C CZ3 . TRP A 1 631 ? -2.049  -1.255  68.358  1.00 82.62  ? 706  TRP A CZ3 1 
ATOM   4899  C CH2 . TRP A 1 631 ? -2.211  -1.036  69.731  1.00 81.38  ? 706  TRP A CH2 1 
ATOM   4900  N N   . ASP A 1 632 ? -6.396  -1.270  62.891  1.00 90.67  ? 707  ASP A N   1 
ATOM   4901  C CA  . ASP A 1 632 ? -7.142  -1.346  61.632  1.00 95.42  ? 707  ASP A CA  1 
ATOM   4902  C C   . ASP A 1 632 ? -7.460  0.045   61.083  1.00 94.69  ? 707  ASP A C   1 
ATOM   4903  O O   . ASP A 1 632 ? -8.583  0.324   60.658  1.00 110.41 ? 707  ASP A O   1 
ATOM   4904  C CB  . ASP A 1 632 ? -8.424  -2.162  61.822  1.00 75.17  ? 707  ASP A CB  1 
ATOM   4905  C CG  . ASP A 1 632 ? -8.897  -2.818  60.546  1.00 93.60  ? 707  ASP A CG  1 
ATOM   4906  O OD1 . ASP A 1 632 ? -9.314  -2.102  59.614  1.00 100.96 ? 707  ASP A OD1 1 
ATOM   4907  O OD2 . ASP A 1 632 ? -8.862  -4.064  60.484  1.00 99.14  ? 707  ASP A OD2 1 
ATOM   4908  N N   . LEU A 1 633 ? -6.459  0.923   61.079  1.00 81.04  ? 708  LEU A N   1 
ATOM   4909  C CA  . LEU A 1 633 ? -6.675  2.334   60.781  1.00 80.51  ? 708  LEU A CA  1 
ATOM   4910  C C   . LEU A 1 633 ? -6.718  2.643   59.291  1.00 72.56  ? 708  LEU A C   1 
ATOM   4911  O O   . LEU A 1 633 ? -6.841  3.819   58.931  1.00 62.14  ? 708  LEU A O   1 
ATOM   4912  C CB  . LEU A 1 633 ? -5.587  3.181   61.444  1.00 88.11  ? 708  LEU A CB  1 
ATOM   4913  C CG  . LEU A 1 633 ? -5.394  2.996   62.951  1.00 86.89  ? 708  LEU A CG  1 
ATOM   4914  C CD1 . LEU A 1 633 ? -3.945  2.670   63.277  1.00 85.81  ? 708  LEU A CD1 1 
ATOM   4915  C CD2 . LEU A 1 633 ? -5.853  4.230   63.709  1.00 92.21  ? 708  LEU A CD2 1 
ATOM   4916  N N   . PHE A 1 634 ? -6.614  1.635   58.421  1.00 76.12  ? 709  PHE A N   1 
ATOM   4917  C CA  . PHE A 1 634 ? -6.690  1.896   56.985  1.00 90.75  ? 709  PHE A CA  1 
ATOM   4918  C C   . PHE A 1 634 ? -8.034  2.497   56.598  1.00 92.27  ? 709  PHE A C   1 
ATOM   4919  O O   . PHE A 1 634 ? -8.102  3.365   55.719  1.00 81.18  ? 709  PHE A O   1 
ATOM   4920  C CB  . PHE A 1 634 ? -6.445  0.613   56.193  1.00 87.47  ? 709  PHE A CB  1 
ATOM   4921  C CG  . PHE A 1 634 ? -6.284  0.843   54.719  1.00 77.75  ? 709  PHE A CG  1 
ATOM   4922  C CD1 . PHE A 1 634 ? -5.152  1.460   54.211  1.00 98.36  ? 709  PHE A CD1 1 
ATOM   4923  C CD2 . PHE A 1 634 ? -7.287  0.472   53.842  1.00 63.58  ? 709  PHE A CD2 1 
ATOM   4924  C CE1 . PHE A 1 634 ? -5.018  1.680   52.850  1.00 100.16 ? 709  PHE A CE1 1 
ATOM   4925  C CE2 . PHE A 1 634 ? -7.161  0.691   52.485  1.00 70.00  ? 709  PHE A CE2 1 
ATOM   4926  C CZ  . PHE A 1 634 ? -6.025  1.294   51.987  1.00 85.00  ? 709  PHE A CZ  1 
ATOM   4927  N N   . ALA A 1 635 ? -9.116  2.038   57.233  1.00 92.67  ? 710  ALA A N   1 
ATOM   4928  C CA  . ALA A 1 635 ? -10.449 2.525   56.892  1.00 81.33  ? 710  ALA A CA  1 
ATOM   4929  C C   . ALA A 1 635 ? -10.542 4.039   57.050  1.00 83.02  ? 710  ALA A C   1 
ATOM   4930  O O   . ALA A 1 635 ? -11.030 4.742   56.156  1.00 74.26  ? 710  ALA A O   1 
ATOM   4931  C CB  . ALA A 1 635 ? -11.495 1.823   57.760  1.00 83.79  ? 710  ALA A CB  1 
ATOM   4932  N N   . CYS A 1 636 ? -10.063 4.555   58.185  1.00 81.53  ? 711  CYS A N   1 
ATOM   4933  C CA  . CYS A 1 636 ? -10.171 5.983   58.468  1.00 71.30  ? 711  CYS A CA  1 
ATOM   4934  C C   . CYS A 1 636 ? -9.379  6.806   57.457  1.00 79.22  ? 711  CYS A C   1 
ATOM   4935  O O   . CYS A 1 636 ? -9.889  7.789   56.901  1.00 73.13  ? 711  CYS A O   1 
ATOM   4936  C CB  . CYS A 1 636 ? -9.698  6.258   59.896  1.00 63.80  ? 711  CYS A CB  1 
ATOM   4937  S SG  . CYS A 1 636 ? -10.184 4.990   61.083  1.00 98.36  ? 711  CYS A SG  1 
ATOM   4938  N N   . ASN A 1 637 ? -8.129  6.408   57.198  1.00 82.29  ? 712  ASN A N   1 
ATOM   4939  C CA  . ASN A 1 637 ? -7.292  7.134   56.248  1.00 77.93  ? 712  ASN A CA  1 
ATOM   4940  C C   . ASN A 1 637 ? -7.898  7.116   54.852  1.00 89.49  ? 712  ASN A C   1 
ATOM   4941  O O   . ASN A 1 637 ? -7.930  8.147   54.168  1.00 88.57  ? 712  ASN A O   1 
ATOM   4942  C CB  . ASN A 1 637 ? -5.883  6.539   56.224  1.00 69.98  ? 712  ASN A CB  1 
ATOM   4943  C CG  . ASN A 1 637 ? -5.253  6.474   57.600  1.00 71.31  ? 712  ASN A CG  1 
ATOM   4944  O OD1 . ASN A 1 637 ? -5.259  7.457   58.342  1.00 63.55  ? 712  ASN A OD1 1 
ATOM   4945  N ND2 . ASN A 1 637 ? -4.714  5.311   57.953  1.00 85.91  ? 712  ASN A ND2 1 
ATOM   4946  N N   . TYR A 1 638 ? -8.393  5.954   54.414  1.00 89.28  ? 713  TYR A N   1 
ATOM   4947  C CA  . TYR A 1 638 ? -8.973  5.856   53.077  1.00 89.05  ? 713  TYR A CA  1 
ATOM   4948  C C   . TYR A 1 638 ? -10.223 6.714   52.956  1.00 89.65  ? 713  TYR A C   1 
ATOM   4949  O O   . TYR A 1 638 ? -10.443 7.363   51.926  1.00 86.36  ? 713  TYR A O   1 
ATOM   4950  C CB  . TYR A 1 638 ? -9.305  4.405   52.739  1.00 86.43  ? 713  TYR A CB  1 
ATOM   4951  C CG  . TYR A 1 638 ? -10.394 4.287   51.698  1.00 96.04  ? 713  TYR A CG  1 
ATOM   4952  C CD1 . TYR A 1 638 ? -10.163 4.663   50.381  1.00 101.90 ? 713  TYR A CD1 1 
ATOM   4953  C CD2 . TYR A 1 638 ? -11.660 3.829   52.036  1.00 102.65 ? 713  TYR A CD2 1 
ATOM   4954  C CE1 . TYR A 1 638 ? -11.155 4.571   49.426  1.00 92.01  ? 713  TYR A CE1 1 
ATOM   4955  C CE2 . TYR A 1 638 ? -12.660 3.734   51.088  1.00 126.55 ? 713  TYR A CE2 1 
ATOM   4956  C CZ  . TYR A 1 638 ? -12.401 4.106   49.783  1.00 115.60 ? 713  TYR A CZ  1 
ATOM   4957  O OH  . TYR A 1 638 ? -13.389 4.014   48.831  1.00 148.90 ? 713  TYR A OH  1 
ATOM   4958  N N   . LYS A 1 639 ? -11.073 6.704   53.985  1.00 91.51  ? 714  LYS A N   1 
ATOM   4959  C CA  . LYS A 1 639 ? -12.276 7.525   53.942  1.00 87.43  ? 714  LYS A CA  1 
ATOM   4960  C C   . LYS A 1 639 ? -11.921 9.005   53.888  1.00 86.93  ? 714  LYS A C   1 
ATOM   4961  O O   . LYS A 1 639 ? -12.483 9.754   53.079  1.00 96.50  ? 714  LYS A O   1 
ATOM   4962  C CB  . LYS A 1 639 ? -13.167 7.202   55.140  1.00 86.29  ? 714  LYS A CB  1 
ATOM   4963  C CG  . LYS A 1 639 ? -14.000 5.934   54.952  1.00 91.18  ? 714  LYS A CG  1 
ATOM   4964  C CD  . LYS A 1 639 ? -14.303 5.204   56.262  1.00 105.57 ? 714  LYS A CD  1 
ATOM   4965  C CE  . LYS A 1 639 ? -14.284 6.125   57.476  1.00 129.47 ? 714  LYS A CE  1 
ATOM   4966  N NZ  . LYS A 1 639 ? -13.929 5.385   58.723  1.00 134.51 ? 714  LYS A NZ  1 
ATOM   4967  N N   . LEU A 1 640 ? -10.964 9.437   54.717  1.00 84.36  ? 715  LEU A N   1 
ATOM   4968  C CA  . LEU A 1 640 ? -10.487 10.816  54.652  1.00 88.09  ? 715  LEU A CA  1 
ATOM   4969  C C   . LEU A 1 640 ? -9.979  11.164  53.257  1.00 93.39  ? 715  LEU A C   1 
ATOM   4970  O O   . LEU A 1 640 ? -10.304 12.228  52.717  1.00 93.31  ? 715  LEU A O   1 
ATOM   4971  C CB  . LEU A 1 640 ? -9.385  11.035  55.689  1.00 82.57  ? 715  LEU A CB  1 
ATOM   4972  C CG  . LEU A 1 640 ? -9.773  11.638  57.039  1.00 75.03  ? 715  LEU A CG  1 
ATOM   4973  C CD1 . LEU A 1 640 ? -8.536  11.853  57.896  1.00 65.74  ? 715  LEU A CD1 1 
ATOM   4974  C CD2 . LEU A 1 640 ? -10.517 12.950  56.843  1.00 78.22  ? 715  LEU A CD2 1 
ATOM   4975  N N   . LEU A 1 641 ? -9.193  10.268  52.651  1.00 90.83  ? 716  LEU A N   1 
ATOM   4976  C CA  . LEU A 1 641 ? -8.566  10.566  51.366  1.00 102.11 ? 716  LEU A CA  1 
ATOM   4977  C C   . LEU A 1 641 ? -9.596  10.648  50.245  1.00 100.86 ? 716  LEU A C   1 
ATOM   4978  O O   . LEU A 1 641 ? -9.559  11.573  49.423  1.00 105.28 ? 716  LEU A O   1 
ATOM   4979  C CB  . LEU A 1 641 ? -7.509  9.508   51.051  1.00 93.89  ? 716  LEU A CB  1 
ATOM   4980  C CG  . LEU A 1 641 ? -6.208  9.606   51.850  1.00 77.10  ? 716  LEU A CG  1 
ATOM   4981  C CD1 . LEU A 1 641 ? -5.323  8.393   51.596  1.00 70.46  ? 716  LEU A CD1 1 
ATOM   4982  C CD2 . LEU A 1 641 ? -5.466  10.899  51.541  1.00 73.02  ? 716  LEU A CD2 1 
ATOM   4983  N N   . LYS A 1 642 ? -10.525 9.690   50.192  1.00 90.77  ? 717  LYS A N   1 
ATOM   4984  C CA  . LYS A 1 642 ? -11.554 9.746   49.160  1.00 87.82  ? 717  LYS A CA  1 
ATOM   4985  C C   . LYS A 1 642 ? -12.480 10.937  49.364  1.00 96.82  ? 717  LYS A C   1 
ATOM   4986  O O   . LYS A 1 642 ? -12.940 11.533  48.383  1.00 106.06 ? 717  LYS A O   1 
ATOM   4987  C CB  . LYS A 1 642 ? -12.353 8.441   49.119  1.00 71.61  ? 717  LYS A CB  1 
ATOM   4988  C CG  . LYS A 1 642 ? -13.163 8.135   50.367  1.00 107.48 ? 717  LYS A CG  1 
ATOM   4989  C CD  . LYS A 1 642 ? -14.374 7.280   50.015  1.00 124.10 ? 717  LYS A CD  1 
ATOM   4990  C CE  . LYS A 1 642 ? -15.223 6.973   51.238  1.00 125.35 ? 717  LYS A CE  1 
ATOM   4991  N NZ  . LYS A 1 642 ? -15.394 8.175   52.103  1.00 129.29 ? 717  LYS A NZ  1 
ATOM   4992  N N   . THR A 1 643 ? -12.749 11.318  50.619  1.00 103.98 ? 718  THR A N   1 
ATOM   4993  C CA  . THR A 1 643 ? -13.550 12.513  50.860  1.00 99.10  ? 718  THR A CA  1 
ATOM   4994  C C   . THR A 1 643 ? -12.810 13.763  50.403  1.00 97.11  ? 718  THR A C   1 
ATOM   4995  O O   . THR A 1 643 ? -13.424 14.702  49.884  1.00 93.76  ? 718  THR A O   1 
ATOM   4996  C CB  . THR A 1 643 ? -13.919 12.613  52.342  1.00 86.07  ? 718  THR A CB  1 
ATOM   4997  O OG1 . THR A 1 643 ? -14.495 11.376  52.781  1.00 77.07  ? 718  THR A OG1 1 
ATOM   4998  C CG2 . THR A 1 643 ? -14.913 13.744  52.577  1.00 94.53  ? 718  THR A CG2 1 
ATOM   4999  N N   . GLY A 1 644 ? -11.490 13.795  50.590  1.00 104.14 ? 719  GLY A N   1 
ATOM   5000  C CA  . GLY A 1 644 ? -10.707 14.895  50.057  1.00 103.36 ? 719  GLY A CA  1 
ATOM   5001  C C   . GLY A 1 644 ? -10.705 14.937  48.543  1.00 106.52 ? 719  GLY A C   1 
ATOM   5002  O O   . GLY A 1 644 ? -10.664 16.018  47.948  1.00 102.71 ? 719  GLY A O   1 
ATOM   5003  N N   . ILE A 1 645 ? -10.744 13.769  47.902  1.00 106.16 ? 720  ILE A N   1 
ATOM   5004  C CA  . ILE A 1 645 ? -10.807 13.725  46.443  1.00 110.04 ? 720  ILE A CA  1 
ATOM   5005  C C   . ILE A 1 645 ? -12.151 14.249  45.951  1.00 115.01 ? 720  ILE A C   1 
ATOM   5006  O O   . ILE A 1 645 ? -12.217 15.027  44.990  1.00 110.57 ? 720  ILE A O   1 
ATOM   5007  C CB  . ILE A 1 645 ? -10.536 12.296  45.938  1.00 106.63 ? 720  ILE A CB  1 
ATOM   5008  C CG1 . ILE A 1 645 ? -9.058  11.952  46.111  1.00 114.21 ? 720  ILE A CG1 1 
ATOM   5009  C CG2 . ILE A 1 645 ? -10.959 12.141  44.480  1.00 124.87 ? 720  ILE A CG2 1 
ATOM   5010  C CD1 . ILE A 1 645 ? -8.148  12.788  45.248  1.00 116.96 ? 720  ILE A CD1 1 
ATOM   5011  N N   . GLU A 1 646 ? -13.240 13.836  46.599  1.00 120.48 ? 721  GLU A N   1 
ATOM   5012  C CA  . GLU A 1 646 ? -14.575 14.241  46.153  1.00 106.87 ? 721  GLU A CA  1 
ATOM   5013  C C   . GLU A 1 646 ? -14.882 15.687  46.538  1.00 99.77  ? 721  GLU A C   1 
ATOM   5014  O O   . GLU A 1 646 ? -15.011 16.559  45.673  1.00 100.68 ? 721  GLU A O   1 
ATOM   5015  C CB  . GLU A 1 646 ? -15.633 13.296  46.729  1.00 92.28  ? 721  GLU A CB  1 
ATOM   5016  C CG  . GLU A 1 646 ? -15.412 11.834  46.403  1.00 104.73 ? 721  GLU A CG  1 
ATOM   5017  C CD  . GLU A 1 646 ? -15.766 10.932  47.565  1.00 112.51 ? 721  GLU A CD  1 
ATOM   5018  O OE1 . GLU A 1 646 ? -16.230 11.460  48.599  1.00 100.87 ? 721  GLU A OE1 1 
ATOM   5019  O OE2 . GLU A 1 646 ? -15.585 9.702   47.448  1.00 119.65 ? 721  GLU A OE2 1 
ATOM   5020  N N   . ASN A 1 647 ? -15.012 15.946  47.841  1.00 100.30 ? 722  ASN A N   1 
ATOM   5021  C CA  . ASN A 1 647 ? -15.402 17.269  48.320  1.00 105.17 ? 722  ASN A CA  1 
ATOM   5022  C C   . ASN A 1 647 ? -14.433 18.347  47.844  1.00 100.28 ? 722  ASN A C   1 
ATOM   5023  O O   . ASN A 1 647 ? -14.854 19.405  47.361  1.00 110.31 ? 722  ASN A O   1 
ATOM   5024  C CB  . ASN A 1 647 ? -15.483 17.254  49.846  1.00 117.82 ? 722  ASN A CB  1 
ATOM   5025  C CG  . ASN A 1 647 ? -16.481 16.245  50.372  1.00 127.64 ? 722  ASN A CG  1 
ATOM   5026  O OD1 . ASN A 1 647 ? -16.765 15.238  49.722  1.00 134.12 ? 722  ASN A OD1 1 
ATOM   5027  N ND2 . ASN A 1 647 ? -17.006 16.499  51.564  1.00 119.90 ? 722  ASN A ND2 1 
ATOM   5028  N N   . GLY A 1 648 ? -13.132 18.101  47.981  1.00 93.86  ? 723  GLY A N   1 
ATOM   5029  C CA  . GLY A 1 648 ? -12.138 19.055  47.538  1.00 87.08  ? 723  GLY A CA  1 
ATOM   5030  C C   . GLY A 1 648 ? -11.889 20.220  48.466  1.00 94.28  ? 723  GLY A C   1 
ATOM   5031  O O   . GLY A 1 648 ? -11.227 21.182  48.060  1.00 99.15  ? 723  GLY A O   1 
ATOM   5032  N N   . ASP A 1 649 ? -12.409 20.181  49.690  1.00 103.36 ? 724  ASP A N   1 
ATOM   5033  C CA  . ASP A 1 649 ? -12.108 21.191  50.696  1.00 106.10 ? 724  ASP A CA  1 
ATOM   5034  C C   . ASP A 1 649 ? -11.253 20.639  51.823  1.00 101.18 ? 724  ASP A C   1 
ATOM   5035  O O   . ASP A 1 649 ? -11.020 21.346  52.809  1.00 94.69  ? 724  ASP A O   1 
ATOM   5036  C CB  . ASP A 1 649 ? -13.403 21.766  51.281  1.00 105.96 ? 724  ASP A CB  1 
ATOM   5037  C CG  . ASP A 1 649 ? -14.471 20.716  51.442  1.00 119.46 ? 724  ASP A CG  1 
ATOM   5038  O OD1 . ASP A 1 649 ? -14.158 19.544  51.162  1.00 114.17 ? 724  ASP A OD1 1 
ATOM   5039  O OD2 . ASP A 1 649 ? -15.612 21.049  51.825  1.00 133.85 ? 724  ASP A OD2 1 
ATOM   5040  N N   . MET A 1 650 ? -10.798 19.395  51.707  1.00 91.34  ? 725  MET A N   1 
ATOM   5041  C CA  . MET A 1 650 ? -10.062 18.755  52.785  1.00 74.74  ? 725  MET A CA  1 
ATOM   5042  C C   . MET A 1 650 ? -8.754  19.500  53.034  1.00 91.09  ? 725  MET A C   1 
ATOM   5043  O O   . MET A 1 650 ? -8.079  19.900  52.077  1.00 101.49 ? 725  MET A O   1 
ATOM   5044  C CB  . MET A 1 650 ? -9.776  17.295  52.432  1.00 76.08  ? 725  MET A CB  1 
ATOM   5045  C CG  . MET A 1 650 ? -9.165  16.471  53.551  1.00 75.35  ? 725  MET A CG  1 
ATOM   5046  S SD  . MET A 1 650 ? -10.323 16.158  54.895  1.00 78.51  ? 725  MET A SD  1 
ATOM   5047  C CE  . MET A 1 650 ? -11.615 15.271  54.027  1.00 83.41  ? 725  MET A CE  1 
ATOM   5048  N N   . PRO A 1 651 ? -8.372  19.715  54.293  1.00 86.83  ? 726  PRO A N   1 
ATOM   5049  C CA  . PRO A 1 651 ? -7.095  20.387  54.567  1.00 86.68  ? 726  PRO A CA  1 
ATOM   5050  C C   . PRO A 1 651 ? -5.922  19.614  53.981  1.00 88.84  ? 726  PRO A C   1 
ATOM   5051  O O   . PRO A 1 651 ? -5.894  18.382  53.992  1.00 88.68  ? 726  PRO A O   1 
ATOM   5052  C CB  . PRO A 1 651 ? -7.039  20.429  56.098  1.00 90.98  ? 726  PRO A CB  1 
ATOM   5053  C CG  . PRO A 1 651 ? -8.471  20.352  56.531  1.00 89.82  ? 726  PRO A CG  1 
ATOM   5054  C CD  . PRO A 1 651 ? -9.140  19.459  55.524  1.00 77.87  ? 726  PRO A CD  1 
ATOM   5055  N N   . GLU A 1 652 ? -4.947  20.360  53.454  1.00 89.09  ? 727  GLU A N   1 
ATOM   5056  C CA  . GLU A 1 652 ? -3.811  19.732  52.785  1.00 95.46  ? 727  GLU A CA  1 
ATOM   5057  C C   . GLU A 1 652 ? -2.988  18.890  53.754  1.00 86.26  ? 727  GLU A C   1 
ATOM   5058  O O   . GLU A 1 652 ? -2.528  17.794  53.402  1.00 89.93  ? 727  GLU A O   1 
ATOM   5059  C CB  . GLU A 1 652 ? -2.956  20.807  52.105  1.00 99.02  ? 727  GLU A CB  1 
ATOM   5060  C CG  . GLU A 1 652 ? -2.360  21.852  53.044  1.00 111.97 ? 727  GLU A CG  1 
ATOM   5061  C CD  . GLU A 1 652 ? -0.939  21.539  53.466  1.00 126.17 ? 727  GLU A CD  1 
ATOM   5062  O OE1 . GLU A 1 652 ? -0.272  20.743  52.774  1.00 127.85 ? 727  GLU A OE1 1 
ATOM   5063  O OE2 . GLU A 1 652 ? -0.487  22.093  54.492  1.00 126.49 ? 727  GLU A OE2 1 
ATOM   5064  N N   . GLN A 1 653 ? -2.812  19.373  54.986  1.00 77.64  ? 728  GLN A N   1 
ATOM   5065  C CA  . GLN A 1 653 ? -2.056  18.614  55.976  1.00 85.34  ? 728  GLN A CA  1 
ATOM   5066  C C   . GLN A 1 653 ? -2.756  17.303  56.315  1.00 85.38  ? 728  GLN A C   1 
ATOM   5067  O O   . GLN A 1 653 ? -2.099  16.273  56.531  1.00 95.15  ? 728  GLN A O   1 
ATOM   5068  C CB  . GLN A 1 653 ? -1.857  19.458  57.234  1.00 87.66  ? 728  GLN A CB  1 
ATOM   5069  C CG  . GLN A 1 653 ? -0.720  20.461  57.144  1.00 89.15  ? 728  GLN A CG  1 
ATOM   5070  C CD  . GLN A 1 653 ? 0.642   19.794  57.113  1.00 92.03  ? 728  GLN A CD  1 
ATOM   5071  O OE1 . GLN A 1 653 ? 1.267   19.587  58.153  1.00 100.25 ? 728  GLN A OE1 1 
ATOM   5072  N NE2 . GLN A 1 653 ? 1.121   19.478  55.915  1.00 96.95  ? 728  GLN A NE2 1 
ATOM   5073  N N   . ILE A 1 654 ? -4.090  17.324  56.366  1.00 75.44  ? 729  ILE A N   1 
ATOM   5074  C CA  . ILE A 1 654 ? -4.850  16.107  56.635  1.00 81.12  ? 729  ILE A CA  1 
ATOM   5075  C C   . ILE A 1 654 ? -4.588  15.079  55.545  1.00 82.65  ? 729  ILE A C   1 
ATOM   5076  O O   . ILE A 1 654 ? -4.352  13.897  55.823  1.00 82.49  ? 729  ILE A O   1 
ATOM   5077  C CB  . ILE A 1 654 ? -6.351  16.426  56.756  1.00 81.28  ? 729  ILE A CB  1 
ATOM   5078  C CG1 . ILE A 1 654 ? -6.626  17.178  58.059  1.00 85.93  ? 729  ILE A CG1 1 
ATOM   5079  C CG2 . ILE A 1 654 ? -7.181  15.144  56.682  1.00 74.31  ? 729  ILE A CG2 1 
ATOM   5080  C CD1 . ILE A 1 654 ? -8.084  17.194  58.466  1.00 83.72  ? 729  ILE A CD1 1 
ATOM   5081  N N   . VAL A 1 655 ? -4.613  15.523  54.286  1.00 80.83  ? 730  VAL A N   1 
ATOM   5082  C CA  . VAL A 1 655 ? -4.350  14.627  53.163  1.00 80.86  ? 730  VAL A CA  1 
ATOM   5083  C C   . VAL A 1 655 ? -2.943  14.055  53.252  1.00 79.47  ? 730  VAL A C   1 
ATOM   5084  O O   . VAL A 1 655 ? -2.731  12.857  53.033  1.00 72.21  ? 730  VAL A O   1 
ATOM   5085  C CB  . VAL A 1 655 ? -4.576  15.363  51.830  1.00 76.37  ? 730  VAL A CB  1 
ATOM   5086  C CG1 . VAL A 1 655 ? -4.112  14.505  50.666  1.00 78.15  ? 730  VAL A CG1 1 
ATOM   5087  C CG2 . VAL A 1 655 ? -6.040  15.719  51.670  1.00 85.99  ? 730  VAL A CG2 1 
ATOM   5088  N N   . ILE A 1 656 ? -1.962  14.899  53.576  1.00 83.96  ? 731  ILE A N   1 
ATOM   5089  C CA  . ILE A 1 656 ? -0.572  14.446  53.639  1.00 74.33  ? 731  ILE A CA  1 
ATOM   5090  C C   . ILE A 1 656 ? -0.409  13.363  54.701  1.00 76.64  ? 731  ILE A C   1 
ATOM   5091  O O   . ILE A 1 656 ? 0.112   12.267  54.433  1.00 81.92  ? 731  ILE A O   1 
ATOM   5092  C CB  . ILE A 1 656 ? 0.365   15.641  53.900  1.00 57.61  ? 731  ILE A CB  1 
ATOM   5093  C CG1 . ILE A 1 656 ? 0.585   16.443  52.614  1.00 56.81  ? 731  ILE A CG1 1 
ATOM   5094  C CG2 . ILE A 1 656 ? 1.686   15.165  54.483  1.00 76.51  ? 731  ILE A CG2 1 
ATOM   5095  C CD1 . ILE A 1 656 ? 0.983   17.887  52.848  1.00 77.12  ? 731  ILE A CD1 1 
ATOM   5096  N N   . HIS A 1 657 ? -0.853  13.654  55.928  1.00 67.70  ? 732  HIS A N   1 
ATOM   5097  C CA  . HIS A 1 657 ? -0.683  12.689  57.011  1.00 74.58  ? 732  HIS A CA  1 
ATOM   5098  C C   . HIS A 1 657 ? -1.524  11.435  56.793  1.00 78.10  ? 732  HIS A C   1 
ATOM   5099  O O   . HIS A 1 657 ? -1.107  10.338  57.186  1.00 73.57  ? 732  HIS A O   1 
ATOM   5100  C CB  . HIS A 1 657 ? -1.008  13.344  58.354  1.00 71.99  ? 732  HIS A CB  1 
ATOM   5101  C CG  . HIS A 1 657 ? -0.094  14.477  58.710  1.00 74.50  ? 732  HIS A CG  1 
ATOM   5102  N ND1 . HIS A 1 657 ? -0.427  15.799  58.498  1.00 80.99  ? 732  HIS A ND1 1 
ATOM   5103  C CD2 . HIS A 1 657 ? 1.143   14.486  59.263  1.00 70.44  ? 732  HIS A CD2 1 
ATOM   5104  C CE1 . HIS A 1 657 ? 0.565   16.571  58.906  1.00 71.37  ? 732  HIS A CE1 1 
ATOM   5105  N NE2 . HIS A 1 657 ? 1.529   15.800  59.375  1.00 74.00  ? 732  HIS A NE2 1 
ATOM   5106  N N   . ALA A 1 658 ? -2.684  11.557  56.139  1.00 69.77  ? 733  ALA A N   1 
ATOM   5107  C CA  . ALA A 1 658 ? -3.487  10.374  55.848  1.00 74.49  ? 733  ALA A CA  1 
ATOM   5108  C C   . ALA A 1 658 ? -2.815  9.496   54.799  1.00 71.71  ? 733  ALA A C   1 
ATOM   5109  O O   . ALA A 1 658 ? -2.835  8.263   54.909  1.00 74.83  ? 733  ALA A O   1 
ATOM   5110  C CB  . ALA A 1 658 ? -4.883  10.792  55.391  1.00 85.66  ? 733  ALA A CB  1 
ATOM   5111  N N   . LEU A 1 659 ? -2.232  10.114  53.767  1.00 65.81  ? 734  LEU A N   1 
ATOM   5112  C CA  . LEU A 1 659 ? -1.436  9.368   52.798  1.00 72.29  ? 734  LEU A CA  1 
ATOM   5113  C C   . LEU A 1 659 ? -0.328  8.595   53.498  1.00 77.42  ? 734  LEU A C   1 
ATOM   5114  O O   . LEU A 1 659 ? -0.156  7.388   53.278  1.00 70.51  ? 734  LEU A O   1 
ATOM   5115  C CB  . LEU A 1 659 ? -0.847  10.324  51.757  1.00 58.70  ? 734  LEU A CB  1 
ATOM   5116  C CG  . LEU A 1 659 ? -1.748  10.853  50.639  1.00 58.85  ? 734  LEU A CG  1 
ATOM   5117  C CD1 . LEU A 1 659 ? -1.089  12.036  49.949  1.00 59.26  ? 734  LEU A CD1 1 
ATOM   5118  C CD2 . LEU A 1 659 ? -2.071  9.767   49.630  1.00 57.33  ? 734  LEU A CD2 1 
ATOM   5119  N N   . GLN A 1 660 ? 0.427   9.283   54.363  1.00 74.05  ? 735  GLN A N   1 
ATOM   5120  C CA  . GLN A 1 660 ? 1.513   8.619   55.079  1.00 62.34  ? 735  GLN A CA  1 
ATOM   5121  C C   . GLN A 1 660 ? 0.999   7.458   55.925  1.00 69.14  ? 735  GLN A C   1 
ATOM   5122  O O   . GLN A 1 660 ? 1.603   6.377   55.941  1.00 62.19  ? 735  GLN A O   1 
ATOM   5123  C CB  . GLN A 1 660 ? 2.267   9.619   55.954  1.00 60.33  ? 735  GLN A CB  1 
ATOM   5124  C CG  . GLN A 1 660 ? 2.923   10.760  55.200  1.00 67.67  ? 735  GLN A CG  1 
ATOM   5125  C CD  . GLN A 1 660 ? 3.734   11.648  56.119  1.00 67.15  ? 735  GLN A CD  1 
ATOM   5126  O OE1 . GLN A 1 660 ? 4.077   11.251  57.234  1.00 56.92  ? 735  GLN A OE1 1 
ATOM   5127  N NE2 . GLN A 1 660 ? 4.049   12.853  55.659  1.00 72.05  ? 735  GLN A NE2 1 
ATOM   5128  N N   . CYS A 1 661 ? -0.120  7.658   56.627  1.00 65.59  ? 736  CYS A N   1 
ATOM   5129  C CA  . CYS A 1 661 ? -0.606  6.628   57.540  1.00 60.53  ? 736  CYS A CA  1 
ATOM   5130  C C   . CYS A 1 661 ? -1.115  5.404   56.786  1.00 67.23  ? 736  CYS A C   1 
ATOM   5131  O O   . CYS A 1 661 ? -0.852  4.268   57.194  1.00 69.05  ? 736  CYS A O   1 
ATOM   5132  C CB  . CYS A 1 661 ? -1.695  7.198   58.448  1.00 59.04  ? 736  CYS A CB  1 
ATOM   5133  S SG  . CYS A 1 661 ? -1.815  6.359   60.047  1.00 67.63  ? 736  CYS A SG  1 
ATOM   5134  N N   . ALA A 1 662 ? -1.850  5.612   55.691  1.00 71.30  ? 737  ALA A N   1 
ATOM   5135  C CA  . ALA A 1 662 ? -2.273  4.480   54.870  1.00 70.26  ? 737  ALA A CA  1 
ATOM   5136  C C   . ALA A 1 662 ? -1.069  3.738   54.301  1.00 78.21  ? 737  ALA A C   1 
ATOM   5137  O O   . ALA A 1 662 ? -1.058  2.498   54.239  1.00 83.27  ? 737  ALA A O   1 
ATOM   5138  C CB  . ALA A 1 662 ? -3.188  4.963   53.745  1.00 68.73  ? 737  ALA A CB  1 
ATOM   5139  N N   . HIS A 1 663 ? -0.046  4.487   53.878  1.00 77.56  ? 738  HIS A N   1 
ATOM   5140  C CA  . HIS A 1 663 ? 1.192   3.878   53.408  1.00 71.58  ? 738  HIS A CA  1 
ATOM   5141  C C   . HIS A 1 663 ? 1.795   2.970   54.476  1.00 77.30  ? 738  HIS A C   1 
ATOM   5142  O O   . HIS A 1 663 ? 2.174   1.824   54.195  1.00 72.74  ? 738  HIS A O   1 
ATOM   5143  C CB  . HIS A 1 663 ? 2.163   4.987   53.000  1.00 66.62  ? 738  HIS A CB  1 
ATOM   5144  C CG  . HIS A 1 663 ? 3.555   4.514   52.723  1.00 74.69  ? 738  HIS A CG  1 
ATOM   5145  N ND1 . HIS A 1 663 ? 3.850   3.611   51.725  1.00 79.55  ? 738  HIS A ND1 1 
ATOM   5146  C CD2 . HIS A 1 663 ? 4.737   4.842   53.296  1.00 82.07  ? 738  HIS A CD2 1 
ATOM   5147  C CE1 . HIS A 1 663 ? 5.152   3.392   51.705  1.00 76.61  ? 738  HIS A CE1 1 
ATOM   5148  N NE2 . HIS A 1 663 ? 5.714   4.127   52.647  1.00 81.54  ? 738  HIS A NE2 1 
ATOM   5149  N N   . TYR A 1 664 ? 1.869   3.462   55.717  1.00 73.63  ? 739  TYR A N   1 
ATOM   5150  C CA  . TYR A 1 664 ? 2.437   2.657   56.798  1.00 73.63  ? 739  TYR A CA  1 
ATOM   5151  C C   . TYR A 1 664 ? 1.570   1.442   57.112  1.00 79.65  ? 739  TYR A C   1 
ATOM   5152  O O   . TYR A 1 664 ? 2.096   0.377   57.457  1.00 79.08  ? 739  TYR A O   1 
ATOM   5153  C CB  . TYR A 1 664 ? 2.637   3.497   58.060  1.00 64.24  ? 739  TYR A CB  1 
ATOM   5154  C CG  . TYR A 1 664 ? 3.417   4.777   57.862  1.00 64.58  ? 739  TYR A CG  1 
ATOM   5155  C CD1 . TYR A 1 664 ? 4.504   4.827   56.998  1.00 57.65  ? 739  TYR A CD1 1 
ATOM   5156  C CD2 . TYR A 1 664 ? 3.090   5.926   58.570  1.00 70.81  ? 739  TYR A CD2 1 
ATOM   5157  C CE1 . TYR A 1 664 ? 5.226   5.995   56.826  1.00 54.56  ? 739  TYR A CE1 1 
ATOM   5158  C CE2 . TYR A 1 664 ? 3.805   7.096   58.404  1.00 66.10  ? 739  TYR A CE2 1 
ATOM   5159  C CZ  . TYR A 1 664 ? 4.872   7.126   57.533  1.00 64.69  ? 739  TYR A CZ  1 
ATOM   5160  O OH  . TYR A 1 664 ? 5.585   8.292   57.370  1.00 66.18  ? 739  TYR A OH  1 
ATOM   5161  N N   . VAL A 1 665 ? 0.245   1.585   57.025  1.00 75.06  ? 740  VAL A N   1 
ATOM   5162  C CA  . VAL A 1 665 ? -0.640  0.438   57.226  1.00 77.52  ? 740  VAL A CA  1 
ATOM   5163  C C   . VAL A 1 665 ? -0.309  -0.661  56.226  1.00 84.17  ? 740  VAL A C   1 
ATOM   5164  O O   . VAL A 1 665 ? -0.104  -1.829  56.594  1.00 87.24  ? 740  VAL A O   1 
ATOM   5165  C CB  . VAL A 1 665 ? -2.117  0.861   57.115  1.00 73.71  ? 740  VAL A CB  1 
ATOM   5166  C CG1 . VAL A 1 665 ? -3.016  -0.357  57.223  1.00 82.67  ? 740  VAL A CG1 1 
ATOM   5167  C CG2 . VAL A 1 665 ? -2.474  1.868   58.190  1.00 83.14  ? 740  VAL A CG2 1 
ATOM   5168  N N   . ILE A 1 666 ? -0.258  -0.299  54.942  1.00 81.67  ? 741  ILE A N   1 
ATOM   5169  C CA  . ILE A 1 666 ? 0.053   -1.280  53.904  1.00 81.40  ? 741  ILE A CA  1 
ATOM   5170  C C   . ILE A 1 666 ? 1.417   -1.911  54.158  1.00 91.12  ? 741  ILE A C   1 
ATOM   5171  O O   . ILE A 1 666 ? 1.591   -3.131  54.025  1.00 93.37  ? 741  ILE A O   1 
ATOM   5172  C CB  . ILE A 1 666 ? -0.022  -0.625  52.512  1.00 73.13  ? 741  ILE A CB  1 
ATOM   5173  C CG1 . ILE A 1 666 ? -1.449  -0.155  52.226  1.00 74.87  ? 741  ILE A CG1 1 
ATOM   5174  C CG2 . ILE A 1 666 ? 0.458   -1.588  51.436  1.00 73.41  ? 741  ILE A CG2 1 
ATOM   5175  C CD1 . ILE A 1 666 ? -1.566  0.780   51.043  1.00 73.75  ? 741  ILE A CD1 1 
ATOM   5176  N N   . LEU A 1 667 ? 2.398   -1.095  54.549  1.00 85.35  ? 742  LEU A N   1 
ATOM   5177  C CA  . LEU A 1 667 ? 3.754   -1.598  54.743  1.00 77.74  ? 742  LEU A CA  1 
ATOM   5178  C C   . LEU A 1 667 ? 3.810   -2.609  55.882  1.00 86.25  ? 742  LEU A C   1 
ATOM   5179  O O   . LEU A 1 667 ? 4.408   -3.687  55.752  1.00 99.64  ? 742  LEU A O   1 
ATOM   5180  C CB  . LEU A 1 667 ? 4.696   -0.430  55.023  1.00 78.47  ? 742  LEU A CB  1 
ATOM   5181  C CG  . LEU A 1 667 ? 5.123   0.396   53.813  1.00 79.29  ? 742  LEU A CG  1 
ATOM   5182  C CD1 . LEU A 1 667 ? 6.286   1.285   54.190  1.00 80.79  ? 742  LEU A CD1 1 
ATOM   5183  C CD2 . LEU A 1 667 ? 5.478   -0.501  52.641  1.00 75.32  ? 742  LEU A CD2 1 
ATOM   5184  N N   . TRP A 1 668 ? 3.202   -2.262  57.019  1.00 80.67  ? 743  TRP A N   1 
ATOM   5185  C CA  . TRP A 1 668 ? 3.214   -3.153  58.171  1.00 81.46  ? 743  TRP A CA  1 
ATOM   5186  C C   . TRP A 1 668 ? 2.501   -4.458  57.849  1.00 90.55  ? 743  TRP A C   1 
ATOM   5187  O O   . TRP A 1 668 ? 2.970   -5.541  58.224  1.00 102.44 ? 743  TRP A O   1 
ATOM   5188  C CB  . TRP A 1 668 ? 2.563   -2.460  59.367  1.00 83.52  ? 743  TRP A CB  1 
ATOM   5189  C CG  . TRP A 1 668 ? 3.500   -1.560  60.122  1.00 83.17  ? 743  TRP A CG  1 
ATOM   5190  C CD1 . TRP A 1 668 ? 3.415   -0.202  60.234  1.00 77.23  ? 743  TRP A CD1 1 
ATOM   5191  C CD2 . TRP A 1 668 ? 4.670   -1.948  60.852  1.00 75.15  ? 743  TRP A CD2 1 
ATOM   5192  N NE1 . TRP A 1 668 ? 4.451   0.278   60.996  1.00 74.07  ? 743  TRP A NE1 1 
ATOM   5193  C CE2 . TRP A 1 668 ? 5.237   -0.773  61.386  1.00 76.07  ? 743  TRP A CE2 1 
ATOM   5194  C CE3 . TRP A 1 668 ? 5.292   -3.174  61.110  1.00 73.39  ? 743  TRP A CE3 1 
ATOM   5195  C CZ2 . TRP A 1 668 ? 6.394   -0.788  62.162  1.00 78.51  ? 743  TRP A CZ2 1 
ATOM   5196  C CZ3 . TRP A 1 668 ? 6.441   -3.186  61.881  1.00 75.53  ? 743  TRP A CZ3 1 
ATOM   5197  C CH2 . TRP A 1 668 ? 6.980   -2.002  62.398  1.00 82.98  ? 743  TRP A CH2 1 
ATOM   5198  N N   . GLN A 1 669 ? 1.373   -4.377  57.134  1.00 98.51  ? 744  GLN A N   1 
ATOM   5199  C CA  . GLN A 1 669 ? 0.675   -5.598  56.745  1.00 107.77 ? 744  GLN A CA  1 
ATOM   5200  C C   . GLN A 1 669 ? 1.538   -6.460  55.833  1.00 107.59 ? 744  GLN A C   1 
ATOM   5201  O O   . GLN A 1 669 ? 1.546   -7.691  55.958  1.00 120.48 ? 744  GLN A O   1 
ATOM   5202  C CB  . GLN A 1 669 ? -0.652  -5.258  56.071  1.00 113.68 ? 744  GLN A CB  1 
ATOM   5203  C CG  . GLN A 1 669 ? -1.743  -4.854  57.043  1.00 112.37 ? 744  GLN A CG  1 
ATOM   5204  C CD  . GLN A 1 669 ? -2.797  -3.988  56.394  1.00 121.98 ? 744  GLN A CD  1 
ATOM   5205  O OE1 . GLN A 1 669 ? -2.536  -3.326  55.390  1.00 133.38 ? 744  GLN A OE1 1 
ATOM   5206  N NE2 . GLN A 1 669 ? -3.997  -3.988  56.960  1.00 143.37 ? 744  GLN A NE2 1 
ATOM   5207  N N   . LEU A 1 670 ? 2.279   -5.834  54.913  1.00 104.01 ? 745  LEU A N   1 
ATOM   5208  C CA  . LEU A 1 670 ? 3.213   -6.592  54.084  1.00 104.57 ? 745  LEU A CA  1 
ATOM   5209  C C   . LEU A 1 670 ? 4.243   -7.314  54.941  1.00 105.38 ? 745  LEU A C   1 
ATOM   5210  O O   . LEU A 1 670 ? 4.557   -8.486  54.703  1.00 107.66 ? 745  LEU A O   1 
ATOM   5211  C CB  . LEU A 1 670 ? 3.910   -5.670  53.083  1.00 89.32  ? 745  LEU A CB  1 
ATOM   5212  C CG  . LEU A 1 670 ? 4.959   -6.383  52.225  1.00 76.05  ? 745  LEU A CG  1 
ATOM   5213  C CD1 . LEU A 1 670 ? 4.304   -7.393  51.289  1.00 89.37  ? 745  LEU A CD1 1 
ATOM   5214  C CD2 . LEU A 1 670 ? 5.805   -5.393  51.447  1.00 81.71  ? 745  LEU A CD2 1 
ATOM   5215  N N   . ALA A 1 671 ? 4.787   -6.622  55.945  1.00 107.85 ? 746  ALA A N   1 
ATOM   5216  C CA  . ALA A 1 671 ? 5.744   -7.267  56.842  1.00 102.35 ? 746  ALA A CA  1 
ATOM   5217  C C   . ALA A 1 671 ? 5.115   -8.461  57.551  1.00 115.68 ? 746  ALA A C   1 
ATOM   5218  O O   . ALA A 1 671 ? 5.759   -9.504  57.718  1.00 129.65 ? 746  ALA A O   1 
ATOM   5219  C CB  . ALA A 1 671 ? 6.282   -6.260  57.858  1.00 94.27  ? 746  ALA A CB  1 
ATOM   5220  N N   . LYS A 1 672 ? 3.850   -8.334  57.959  1.00 110.19 ? 747  LYS A N   1 
ATOM   5221  C CA  . LYS A 1 672 ? 3.183   -9.438  58.644  1.00 103.56 ? 747  LYS A CA  1 
ATOM   5222  C C   . LYS A 1 672 ? 2.933   -10.615 57.705  1.00 119.00 ? 747  LYS A C   1 
ATOM   5223  O O   . LYS A 1 672 ? 3.118   -11.774 58.093  1.00 130.47 ? 747  LYS A O   1 
ATOM   5224  C CB  . LYS A 1 672 ? 1.868   -8.957  59.256  1.00 125.76 ? 747  LYS A CB  1 
ATOM   5225  C CG  . LYS A 1 672 ? 2.013   -7.766  60.186  1.00 136.21 ? 747  LYS A CG  1 
ATOM   5226  C CD  . LYS A 1 672 ? 0.686   -7.042  60.347  1.00 144.12 ? 747  LYS A CD  1 
ATOM   5227  C CE  . LYS A 1 672 ? -0.012  -7.424  61.642  1.00 145.19 ? 747  LYS A CE  1 
ATOM   5228  N NZ  . LYS A 1 672 ? 0.951   -7.582  62.766  1.00 163.19 ? 747  LYS A NZ  1 
ATOM   5229  N N   . ILE A 1 673 ? 2.517   -10.341 56.472  1.00 127.52 ? 748  ILE A N   1 
ATOM   5230  C CA  . ILE A 1 673 ? 2.124   -11.410 55.533  1.00 135.69 ? 748  ILE A CA  1 
ATOM   5231  C C   . ILE A 1 673 ? 3.399   -11.849 54.819  1.00 141.86 ? 748  ILE A C   1 
ATOM   5232  O O   . ILE A 1 673 ? 3.707   -11.440 53.697  1.00 150.58 ? 748  ILE A O   1 
ATOM   5233  C CB  . ILE A 1 673 ? 1.031   -10.955 54.562  1.00 144.64 ? 748  ILE A CB  1 
ATOM   5234  C CG1 . ILE A 1 673 ? -0.107  -10.278 55.324  1.00 186.04 ? 748  ILE A CG1 1 
ATOM   5235  C CG2 . ILE A 1 673 ? 0.507   -12.137 53.758  1.00 148.78 ? 748  ILE A CG2 1 
ATOM   5236  C CD1 . ILE A 1 673 ? -1.152  -9.664  54.426  1.00 195.95 ? 748  ILE A CD1 1 
ATOM   5237  N N   . THR A 1 674 ? 4.158   -12.717 55.488  1.00 150.91 ? 749  THR A N   1 
ATOM   5238  C CA  . THR A 1 674 ? 5.340   -13.317 54.887  1.00 164.61 ? 749  THR A CA  1 
ATOM   5239  C C   . THR A 1 674 ? 5.402   -14.829 55.042  1.00 178.33 ? 749  THR A C   1 
ATOM   5240  O O   . THR A 1 674 ? 6.292   -15.452 54.451  1.00 212.33 ? 749  THR A O   1 
ATOM   5241  C CB  . THR A 1 674 ? 6.624   -12.703 55.470  1.00 151.45 ? 749  THR A CB  1 
ATOM   5242  O OG1 . THR A 1 674 ? 7.758   -13.184 54.739  1.00 145.72 ? 749  THR A OG1 1 
ATOM   5243  C CG2 . THR A 1 674 ? 6.779   -13.071 56.935  1.00 150.78 ? 749  THR A CG2 1 
ATOM   5244  N N   . GLU A 1 675 ? 4.503   -15.436 55.813  1.00 175.66 ? 750  GLU A N   1 
ATOM   5245  C CA  . GLU A 1 675 ? 4.414   -16.881 55.940  1.00 179.97 ? 750  GLU A CA  1 
ATOM   5246  C C   . GLU A 1 675 ? 2.996   -17.328 55.614  1.00 194.99 ? 750  GLU A C   1 
ATOM   5247  O O   . GLU A 1 675 ? 2.028   -16.606 55.872  1.00 246.36 ? 750  GLU A O   1 
ATOM   5248  C CB  . GLU A 1 675 ? 4.788   -17.351 57.354  1.00 169.23 ? 750  GLU A CB  1 
ATOM   5249  C CG  . GLU A 1 675 ? 5.832   -16.493 58.048  1.00 165.37 ? 750  GLU A CG  1 
ATOM   5250  C CD  . GLU A 1 675 ? 5.213   -15.445 58.952  1.00 160.63 ? 750  GLU A CD  1 
ATOM   5251  O OE1 . GLU A 1 675 ? 4.391   -14.644 58.458  1.00 158.29 ? 750  GLU A OE1 1 
ATOM   5252  O OE2 . GLU A 1 675 ? 5.550   -15.419 60.154  1.00 154.62 ? 750  GLU A OE2 1 
ATOM   5253  N N   . SER A 1 676 ? 2.881   -18.525 55.033  1.00 199.69 ? 751  SER A N   1 
ATOM   5254  C CA  . SER A 1 676 ? 1.560   -19.102 54.805  1.00 200.42 ? 751  SER A CA  1 
ATOM   5255  C C   . SER A 1 676 ? 0.824   -19.322 56.118  1.00 194.86 ? 751  SER A C   1 
ATOM   5256  O O   . SER A 1 676 ? -0.410  -19.243 56.162  1.00 183.23 ? 751  SER A O   1 
ATOM   5257  C CB  . SER A 1 676 ? 1.683   -20.418 54.034  1.00 198.20 ? 751  SER A CB  1 
ATOM   5258  O OG  . SER A 1 676 ? 2.198   -21.448 54.860  1.00 202.72 ? 751  SER A OG  1 
ATOM   5259  N N   . THR A 1 677 ? 1.566   -19.589 57.196  1.00 191.84 ? 752  THR A N   1 
ATOM   5260  C CA  . THR A 1 677 ? 0.954   -19.742 58.511  1.00 179.44 ? 752  THR A CA  1 
ATOM   5261  C C   . THR A 1 677 ? 0.265   -18.461 58.960  1.00 175.90 ? 752  THR A C   1 
ATOM   5262  O O   . THR A 1 677 ? -0.719  -18.513 59.707  1.00 172.21 ? 752  THR A O   1 
ATOM   5263  C CB  . THR A 1 677 ? 2.013   -20.153 59.535  1.00 164.55 ? 752  THR A CB  1 
ATOM   5264  O OG1 . THR A 1 677 ? 2.733   -18.992 59.971  1.00 157.64 ? 752  THR A OG1 1 
ATOM   5265  C CG2 . THR A 1 677 ? 2.992   -21.140 58.919  1.00 168.16 ? 752  THR A CG2 1 
ATOM   5266  N N   . SER A 1 678 ? 0.763   -17.305 58.517  1.00 181.38 ? 753  SER A N   1 
ATOM   5267  C CA  . SER A 1 678 ? 0.191   -16.035 58.950  1.00 179.39 ? 753  SER A CA  1 
ATOM   5268  C C   . SER A 1 678 ? -1.228  -15.861 58.421  1.00 177.58 ? 753  SER A C   1 
ATOM   5269  O O   . SER A 1 678 ? -2.178  -15.707 59.198  1.00 180.27 ? 753  SER A O   1 
ATOM   5270  C CB  . SER A 1 678 ? 1.088   -14.877 58.505  1.00 179.44 ? 753  SER A CB  1 
ATOM   5271  O OG  . SER A 1 678 ? 0.955   -14.628 57.117  1.00 191.92 ? 753  SER A OG  1 
ATOM   5272  N N   . THR A 1 679 ? -1.391  -15.892 57.099  1.00 170.75 ? 754  THR A N   1 
ATOM   5273  C CA  . THR A 1 679 ? -2.679  -15.653 56.455  1.00 166.37 ? 754  THR A CA  1 
ATOM   5274  C C   . THR A 1 679 ? -2.526  -15.849 54.954  1.00 163.17 ? 754  THR A C   1 
ATOM   5275  O O   . THR A 1 679 ? -1.417  -15.793 54.412  1.00 168.46 ? 754  THR A O   1 
ATOM   5276  C CB  . THR A 1 679 ? -3.203  -14.246 56.733  1.00 161.97 ? 754  THR A CB  1 
ATOM   5277  O OG1 . THR A 1 679 ? -4.405  -14.023 55.987  1.00 136.77 ? 754  THR A OG1 1 
ATOM   5278  C CG2 . THR A 1 679 ? -2.151  -13.219 56.342  1.00 160.50 ? 754  THR A CG2 1 
ATOM   5279  N N   . LYS A 1 680 ? -3.658  -16.067 54.288  1.00 153.25 ? 755  LYS A N   1 
ATOM   5280  C CA  . LYS A 1 680 ? -3.733  -16.126 52.831  1.00 146.91 ? 755  LYS A CA  1 
ATOM   5281  C C   . LYS A 1 680 ? -4.706  -15.113 52.245  1.00 144.12 ? 755  LYS A C   1 
ATOM   5282  O O   . LYS A 1 680 ? -4.423  -14.529 51.195  1.00 133.70 ? 755  LYS A O   1 
ATOM   5283  C CB  . LYS A 1 680 ? -4.132  -17.535 52.360  1.00 140.25 ? 755  LYS A CB  1 
ATOM   5284  C CG  . LYS A 1 680 ? -3.390  -18.705 53.015  1.00 144.43 ? 755  LYS A CG  1 
ATOM   5285  C CD  . LYS A 1 680 ? -1.870  -18.535 53.035  1.00 152.23 ? 755  LYS A CD  1 
ATOM   5286  C CE  . LYS A 1 680 ? -1.290  -18.391 51.632  1.00 140.56 ? 755  LYS A CE  1 
ATOM   5287  N NZ  . LYS A 1 680 ? -0.985  -19.708 51.007  1.00 137.68 ? 755  LYS A NZ  1 
ATOM   5288  N N   . GLU A 1 681 ? -5.859  -14.896 52.886  1.00 159.19 ? 756  GLU A N   1 
ATOM   5289  C CA  . GLU A 1 681 ? -6.830  -13.939 52.360  1.00 161.47 ? 756  GLU A CA  1 
ATOM   5290  C C   . GLU A 1 681 ? -6.394  -12.499 52.616  1.00 160.35 ? 756  GLU A C   1 
ATOM   5291  O O   . GLU A 1 681 ? -6.692  -11.602 51.810  1.00 152.55 ? 756  GLU A O   1 
ATOM   5292  C CB  . GLU A 1 681 ? -8.215  -14.211 52.963  1.00 157.95 ? 756  GLU A CB  1 
ATOM   5293  C CG  . GLU A 1 681 ? -8.556  -13.458 54.258  1.00 156.15 ? 756  GLU A CG  1 
ATOM   5294  C CD  . GLU A 1 681 ? -7.686  -13.845 55.453  1.00 166.08 ? 756  GLU A CD  1 
ATOM   5295  O OE1 . GLU A 1 681 ? -6.683  -14.570 55.281  1.00 163.04 ? 756  GLU A OE1 1 
ATOM   5296  O OE2 . GLU A 1 681 ? -8.007  -13.411 56.579  1.00 172.49 ? 756  GLU A OE2 1 
ATOM   5297  N N   . ASP A 1 682 ? -5.682  -12.261 53.721  1.00 158.42 ? 757  ASP A N   1 
ATOM   5298  C CA  . ASP A 1 682 ? -5.165  -10.928 53.992  1.00 150.77 ? 757  ASP A CA  1 
ATOM   5299  C C   . ASP A 1 682 ? -4.164  -10.490 52.936  1.00 142.37 ? 757  ASP A C   1 
ATOM   5300  O O   . ASP A 1 682 ? -3.980  -9.288  52.739  1.00 137.02 ? 757  ASP A O   1 
ATOM   5301  C CB  . ASP A 1 682 ? -4.517  -10.887 55.376  1.00 153.88 ? 757  ASP A CB  1 
ATOM   5302  C CG  . ASP A 1 682 ? -5.535  -10.870 56.498  1.00 160.04 ? 757  ASP A CG  1 
ATOM   5303  O OD1 . ASP A 1 682 ? -6.573  -10.187 56.353  1.00 160.64 ? 757  ASP A OD1 1 
ATOM   5304  O OD2 . ASP A 1 682 ? -5.295  -11.541 57.526  1.00 159.25 ? 757  ASP A OD2 1 
ATOM   5305  N N   . LEU A 1 683 ? -3.531  -11.437 52.242  1.00 142.72 ? 758  LEU A N   1 
ATOM   5306  C CA  . LEU A 1 683 ? -2.691  -11.093 51.099  1.00 139.17 ? 758  LEU A CA  1 
ATOM   5307  C C   . LEU A 1 683 ? -3.508  -10.410 50.009  1.00 131.41 ? 758  LEU A C   1 
ATOM   5308  O O   . LEU A 1 683 ? -3.104  -9.376  49.463  1.00 126.41 ? 758  LEU A O   1 
ATOM   5309  C CB  . LEU A 1 683 ? -2.017  -12.354 50.556  1.00 125.83 ? 758  LEU A CB  1 
ATOM   5310  C CG  . LEU A 1 683 ? -1.033  -12.199 49.398  1.00 108.20 ? 758  LEU A CG  1 
ATOM   5311  C CD1 . LEU A 1 683 ? 0.272   -12.908 49.717  1.00 112.19 ? 758  LEU A CD1 1 
ATOM   5312  C CD2 . LEU A 1 683 ? -1.630  -12.732 48.101  1.00 126.18 ? 758  LEU A CD2 1 
ATOM   5313  N N   . LEU A 1 684 ? -4.663  -10.988 49.673  1.00 131.60 ? 759  LEU A N   1 
ATOM   5314  C CA  . LEU A 1 684 ? -5.536  -10.379 48.677  1.00 134.36 ? 759  LEU A CA  1 
ATOM   5315  C C   . LEU A 1 684 ? -6.055  -9.030  49.160  1.00 132.38 ? 759  LEU A C   1 
ATOM   5316  O O   . LEU A 1 684 ? -6.126  -8.063  48.385  1.00 137.65 ? 759  LEU A O   1 
ATOM   5317  C CB  . LEU A 1 684 ? -6.697  -11.321 48.368  1.00 141.16 ? 759  LEU A CB  1 
ATOM   5318  C CG  . LEU A 1 684 ? -6.344  -12.809 48.315  1.00 145.46 ? 759  LEU A CG  1 
ATOM   5319  C CD1 . LEU A 1 684 ? -7.603  -13.650 48.176  1.00 146.90 ? 759  LEU A CD1 1 
ATOM   5320  C CD2 . LEU A 1 684 ? -5.371  -13.097 47.181  1.00 133.81 ? 759  LEU A CD2 1 
ATOM   5321  N N   . ARG A 1 685 ? -6.431  -8.950  50.441  1.00 130.78 ? 760  ARG A N   1 
ATOM   5322  C CA  . ARG A 1 685 ? -6.855  -7.669  51.003  1.00 135.40 ? 760  ARG A CA  1 
ATOM   5323  C C   . ARG A 1 685 ? -5.756  -6.618  50.875  1.00 129.12 ? 760  ARG A C   1 
ATOM   5324  O O   . ARG A 1 685 ? -6.025  -5.464  50.518  1.00 122.46 ? 760  ARG A O   1 
ATOM   5325  C CB  . ARG A 1 685 ? -7.262  -7.842  52.468  1.00 136.33 ? 760  ARG A CB  1 
ATOM   5326  C CG  . ARG A 1 685 ? -8.307  -8.921  52.736  1.00 150.18 ? 760  ARG A CG  1 
ATOM   5327  C CD  . ARG A 1 685 ? -9.521  -8.787  51.825  1.00 173.96 ? 760  ARG A CD  1 
ATOM   5328  N NE  . ARG A 1 685 ? -9.565  -9.801  50.778  1.00 187.26 ? 760  ARG A NE  1 
ATOM   5329  C CZ  . ARG A 1 685 ? -9.705  -9.543  49.485  1.00 183.82 ? 760  ARG A CZ  1 
ATOM   5330  N NH1 . ARG A 1 685 ? -9.772  -8.302  49.031  1.00 202.07 ? 760  ARG A NH1 1 
ATOM   5331  N NH2 . ARG A 1 685 ? -9.790  -10.556 48.627  1.00 165.10 ? 760  ARG A NH2 1 
ATOM   5332  N N   . LEU A 1 686 ? -4.509  -7.005  51.156  1.00 127.29 ? 761  LEU A N   1 
ATOM   5333  C CA  . LEU A 1 686 ? -3.384  -6.080  51.069  1.00 108.31 ? 761  LEU A CA  1 
ATOM   5334  C C   . LEU A 1 686 ? -3.143  -5.638  49.634  1.00 101.06 ? 761  LEU A C   1 
ATOM   5335  O O   . LEU A 1 686 ? -2.816  -4.472  49.381  1.00 90.35  ? 761  LEU A O   1 
ATOM   5336  C CB  . LEU A 1 686 ? -2.132  -6.744  51.642  1.00 100.22 ? 761  LEU A CB  1 
ATOM   5337  C CG  . LEU A 1 686 ? -0.814  -5.975  51.560  1.00 95.11  ? 761  LEU A CG  1 
ATOM   5338  C CD1 . LEU A 1 686 ? -0.827  -4.784  52.499  1.00 101.95 ? 761  LEU A CD1 1 
ATOM   5339  C CD2 . LEU A 1 686 ? 0.345   -6.905  51.871  1.00 95.68  ? 761  LEU A CD2 1 
ATOM   5340  N N   . LYS A 1 687 ? -3.279  -6.562  48.682  1.00 105.25 ? 762  LYS A N   1 
ATOM   5341  C CA  . LYS A 1 687 ? -3.138  -6.199  47.276  1.00 109.57 ? 762  LYS A CA  1 
ATOM   5342  C C   . LYS A 1 687 ? -4.171  -5.149  46.889  1.00 113.71 ? 762  LYS A C   1 
ATOM   5343  O O   . LYS A 1 687 ? -3.842  -4.128  46.268  1.00 107.43 ? 762  LYS A O   1 
ATOM   5344  C CB  . LYS A 1 687 ? -3.273  -7.448  46.405  1.00 102.29 ? 762  LYS A CB  1 
ATOM   5345  C CG  . LYS A 1 687 ? -2.685  -7.320  45.011  1.00 123.28 ? 762  LYS A CG  1 
ATOM   5346  C CD  . LYS A 1 687 ? -3.180  -8.450  44.119  1.00 110.13 ? 762  LYS A CD  1 
ATOM   5347  C CE  . LYS A 1 687 ? -3.045  -8.113  42.642  1.00 105.59 ? 762  LYS A CE  1 
ATOM   5348  N NZ  . LYS A 1 687 ? -1.618  -8.009  42.230  1.00 109.15 ? 762  LYS A NZ  1 
ATOM   5349  N N   . LYS A 1 688 ? -5.433  -5.386  47.263  1.00 113.46 ? 763  LYS A N   1 
ATOM   5350  C CA  . LYS A 1 688 ? -6.487  -4.418  46.975  1.00 112.36 ? 763  LYS A CA  1 
ATOM   5351  C C   . LYS A 1 688 ? -6.188  -3.069  47.620  1.00 111.54 ? 763  LYS A C   1 
ATOM   5352  O O   . LYS A 1 688 ? -6.352  -2.016  46.986  1.00 98.20  ? 763  LYS A O   1 
ATOM   5353  C CB  . LYS A 1 688 ? -7.837  -4.960  47.447  1.00 134.81 ? 763  LYS A CB  1 
ATOM   5354  C CG  . LYS A 1 688 ? -8.998  -3.979  47.331  1.00 164.82 ? 763  LYS A CG  1 
ATOM   5355  C CD  . LYS A 1 688 ? -10.019 -4.207  48.439  1.00 169.53 ? 763  LYS A CD  1 
ATOM   5356  C CE  . LYS A 1 688 ? -9.490  -3.770  49.798  1.00 175.95 ? 763  LYS A CE  1 
ATOM   5357  N NZ  . LYS A 1 688 ? -8.982  -2.371  49.789  1.00 198.14 ? 763  LYS A NZ  1 
ATOM   5358  N N   . GLN A 1 689 ? -5.742  -3.083  48.880  1.00 107.74 ? 764  GLN A N   1 
ATOM   5359  C CA  . GLN A 1 689 ? -5.419  -1.839  49.570  1.00 101.01 ? 764  GLN A CA  1 
ATOM   5360  C C   . GLN A 1 689 ? -4.327  -1.074  48.834  1.00 97.10  ? 764  GLN A C   1 
ATOM   5361  O O   . GLN A 1 689 ? -4.429  0.142   48.638  1.00 94.27  ? 764  GLN A O   1 
ATOM   5362  C CB  . GLN A 1 689 ? -4.991  -2.128  51.009  1.00 97.68  ? 764  GLN A CB  1 
ATOM   5363  C CG  . GLN A 1 689 ? -6.109  -2.593  51.927  1.00 100.01 ? 764  GLN A CG  1 
ATOM   5364  C CD  . GLN A 1 689 ? -5.588  -3.069  53.269  1.00 108.87 ? 764  GLN A CD  1 
ATOM   5365  O OE1 . GLN A 1 689 ? -5.644  -4.256  53.589  1.00 127.84 ? 764  GLN A OE1 1 
ATOM   5366  N NE2 . GLN A 1 689 ? -5.071  -2.138  54.063  1.00 102.91 ? 764  GLN A NE2 1 
ATOM   5367  N N   . MET A 1 690 ? -3.274  -1.777  48.409  1.00 89.05  ? 765  MET A N   1 
ATOM   5368  C CA  . MET A 1 690 ? -2.154  -1.107  47.754  1.00 98.77  ? 765  MET A CA  1 
ATOM   5369  C C   . MET A 1 690 ? -2.583  -0.493  46.430  1.00 96.57  ? 765  MET A C   1 
ATOM   5370  O O   . MET A 1 690 ? -2.218  0.645   46.115  1.00 87.51  ? 765  MET A O   1 
ATOM   5371  C CB  . MET A 1 690 ? -1.000  -2.082  47.532  1.00 92.89  ? 765  MET A CB  1 
ATOM   5372  C CG  . MET A 1 690 ? 0.210   -1.421  46.891  1.00 93.64  ? 765  MET A CG  1 
ATOM   5373  S SD  . MET A 1 690 ? 0.407   -1.805  45.142  1.00 94.78  ? 765  MET A SD  1 
ATOM   5374  C CE  . MET A 1 690 ? 0.328   -3.594  45.168  1.00 91.81  ? 765  MET A CE  1 
ATOM   5375  N N   . ARG A 1 691 ? -3.355  -1.236  45.634  1.00 98.96  ? 766  ARG A N   1 
ATOM   5376  C CA  . ARG A 1 691 ? -3.790  -0.709  44.342  1.00 96.25  ? 766  ARG A CA  1 
ATOM   5377  C C   . ARG A 1 691 ? -4.702  0.502   44.520  1.00 95.25  ? 766  ARG A C   1 
ATOM   5378  O O   . ARG A 1 691 ? -4.548  1.521   43.829  1.00 90.92  ? 766  ARG A O   1 
ATOM   5379  C CB  . ARG A 1 691 ? -4.480  -1.810  43.537  1.00 96.34  ? 766  ARG A CB  1 
ATOM   5380  C CG  . ARG A 1 691 ? -3.645  -3.082  43.432  1.00 96.39  ? 766  ARG A CG  1 
ATOM   5381  C CD  . ARG A 1 691 ? -4.000  -3.945  42.225  1.00 114.63 ? 766  ARG A CD  1 
ATOM   5382  N NE  . ARG A 1 691 ? -3.010  -3.899  41.155  1.00 122.89 ? 766  ARG A NE  1 
ATOM   5383  C CZ  . ARG A 1 691 ? -1.836  -4.518  41.181  1.00 126.57 ? 766  ARG A CZ  1 
ATOM   5384  N NH1 . ARG A 1 691 ? -1.417  -5.162  42.258  1.00 148.35 ? 766  ARG A NH1 1 
ATOM   5385  N NH2 . ARG A 1 691 ? -1.062  -4.489  40.100  1.00 136.85 ? 766  ARG A NH2 1 
ATOM   5386  N N   . VAL A 1 692 ? -5.653  0.414   45.455  1.00 95.74  ? 767  VAL A N   1 
ATOM   5387  C CA  . VAL A 1 692 ? -6.551  1.537   45.720  1.00 101.51 ? 767  VAL A CA  1 
ATOM   5388  C C   . VAL A 1 692 ? -5.754  2.760   46.158  1.00 99.84  ? 767  VAL A C   1 
ATOM   5389  O O   . VAL A 1 692 ? -5.975  3.882   45.677  1.00 94.44  ? 767  VAL A O   1 
ATOM   5390  C CB  . VAL A 1 692 ? -7.600  1.134   46.773  1.00 90.40  ? 767  VAL A CB  1 
ATOM   5391  C CG1 . VAL A 1 692 ? -8.206  2.361   47.433  1.00 98.29  ? 767  VAL A CG1 1 
ATOM   5392  C CG2 . VAL A 1 692 ? -8.674  0.259   46.145  1.00 98.29  ? 767  VAL A CG2 1 
ATOM   5393  N N   . PHE A 1 693 ? -4.803  2.555   47.070  1.00 84.56  ? 768  PHE A N   1 
ATOM   5394  C CA  . PHE A 1 693 ? -3.999  3.659   47.571  1.00 85.51  ? 768  PHE A CA  1 
ATOM   5395  C C   . PHE A 1 693 ? -3.135  4.261   46.473  1.00 94.05  ? 768  PHE A C   1 
ATOM   5396  O O   . PHE A 1 693 ? -2.910  5.475   46.456  1.00 91.49  ? 768  PHE A O   1 
ATOM   5397  C CB  . PHE A 1 693 ? -3.141  3.168   48.734  1.00 75.25  ? 768  PHE A CB  1 
ATOM   5398  C CG  . PHE A 1 693 ? -2.245  4.212   49.312  1.00 77.22  ? 768  PHE A CG  1 
ATOM   5399  C CD1 . PHE A 1 693 ? -2.768  5.397   49.795  1.00 76.20  ? 768  PHE A CD1 1 
ATOM   5400  C CD2 . PHE A 1 693 ? -0.880  4.007   49.385  1.00 86.48  ? 768  PHE A CD2 1 
ATOM   5401  C CE1 . PHE A 1 693 ? -1.946  6.363   50.334  1.00 82.17  ? 768  PHE A CE1 1 
ATOM   5402  C CE2 . PHE A 1 693 ? -0.054  4.968   49.922  1.00 92.08  ? 768  PHE A CE2 1 
ATOM   5403  C CZ  . PHE A 1 693 ? -0.586  6.149   50.398  1.00 84.12  ? 768  PHE A CZ  1 
ATOM   5404  N N   . CYS A 1 694 ? -2.650  3.432   45.545  1.00 90.40  ? 769  CYS A N   1 
ATOM   5405  C CA  . CYS A 1 694 ? -1.890  3.949   44.412  1.00 92.35  ? 769  CYS A CA  1 
ATOM   5406  C C   . CYS A 1 694 ? -2.759  4.829   43.526  1.00 104.96 ? 769  CYS A C   1 
ATOM   5407  O O   . CYS A 1 694 ? -2.313  5.884   43.059  1.00 101.87 ? 769  CYS A O   1 
ATOM   5408  C CB  . CYS A 1 694 ? -1.296  2.796   43.602  1.00 89.16  ? 769  CYS A CB  1 
ATOM   5409  S SG  . CYS A 1 694 ? 0.096   1.954   44.390  1.00 96.44  ? 769  CYS A SG  1 
ATOM   5410  N N   . GLN A 1 695 ? -4.002  4.408   43.274  1.00 105.10 ? 770  GLN A N   1 
ATOM   5411  C CA  . GLN A 1 695 ? -4.920  5.275   42.537  1.00 107.92 ? 770  GLN A CA  1 
ATOM   5412  C C   . GLN A 1 695 ? -5.129  6.598   43.264  1.00 106.06 ? 770  GLN A C   1 
ATOM   5413  O O   . GLN A 1 695 ? -5.176  7.665   42.636  1.00 115.12 ? 770  GLN A O   1 
ATOM   5414  C CB  . GLN A 1 695 ? -6.262  4.579   42.314  1.00 108.34 ? 770  GLN A CB  1 
ATOM   5415  C CG  . GLN A 1 695 ? -6.330  3.746   41.054  1.00 105.21 ? 770  GLN A CG  1 
ATOM   5416  C CD  . GLN A 1 695 ? -5.947  2.308   41.296  1.00 121.18 ? 770  GLN A CD  1 
ATOM   5417  O OE1 . GLN A 1 695 ? -6.763  1.506   41.749  1.00 115.04 ? 770  GLN A OE1 1 
ATOM   5418  N NE2 . GLN A 1 695 ? -4.696  1.971   41.003  1.00 128.86 ? 770  GLN A NE2 1 
ATOM   5419  N N   . ILE A 1 696 ? -5.261  6.545   44.590  1.00 98.59  ? 771  ILE A N   1 
ATOM   5420  C CA  . ILE A 1 696 ? -5.471  7.770   45.361  1.00 98.04  ? 771  ILE A CA  1 
ATOM   5421  C C   . ILE A 1 696 ? -4.257  8.689   45.249  1.00 99.14  ? 771  ILE A C   1 
ATOM   5422  O O   . ILE A 1 696 ? -4.392  9.913   45.093  1.00 87.56  ? 771  ILE A O   1 
ATOM   5423  C CB  . ILE A 1 696 ? -5.800  7.427   46.826  1.00 82.87  ? 771  ILE A CB  1 
ATOM   5424  C CG1 . ILE A 1 696 ? -7.243  6.931   46.941  1.00 70.26  ? 771  ILE A CG1 1 
ATOM   5425  C CG2 . ILE A 1 696 ? -5.582  8.632   47.726  1.00 75.88  ? 771  ILE A CG2 1 
ATOM   5426  C CD1 . ILE A 1 696 ? -7.566  6.289   48.271  1.00 67.65  ? 771  ILE A CD1 1 
ATOM   5427  N N   . CYS A 1 697 ? -3.053  8.115   45.321  1.00 98.85  ? 772  CYS A N   1 
ATOM   5428  C CA  . CYS A 1 697 ? -1.844  8.918   45.165  1.00 101.47 ? 772  CYS A CA  1 
ATOM   5429  C C   . CYS A 1 697 ? -1.731  9.491   43.760  1.00 97.85  ? 772  CYS A C   1 
ATOM   5430  O O   . CYS A 1 697 ? -1.195  10.590  43.583  1.00 89.63  ? 772  CYS A O   1 
ATOM   5431  C CB  . CYS A 1 697 ? -0.596  8.096   45.500  1.00 93.48  ? 772  CYS A CB  1 
ATOM   5432  S SG  . CYS A 1 697 ? -0.609  7.286   47.112  1.00 92.68  ? 772  CYS A SG  1 
ATOM   5433  N N   . GLN A 1 698 ? -2.218  8.769   42.749  1.00 95.39  ? 773  GLN A N   1 
ATOM   5434  C CA  . GLN A 1 698 ? -2.209  9.323   41.399  1.00 101.41 ? 773  GLN A CA  1 
ATOM   5435  C C   . GLN A 1 698 ? -3.165  10.502  41.285  1.00 115.99 ? 773  GLN A C   1 
ATOM   5436  O O   . GLN A 1 698 ? -2.853  11.502  40.627  1.00 120.15 ? 773  GLN A O   1 
ATOM   5437  C CB  . GLN A 1 698 ? -2.565  8.251   40.372  1.00 99.24  ? 773  GLN A CB  1 
ATOM   5438  C CG  . GLN A 1 698 ? -1.483  7.216   40.144  1.00 99.46  ? 773  GLN A CG  1 
ATOM   5439  C CD  . GLN A 1 698 ? -2.015  5.974   39.462  1.00 100.25 ? 773  GLN A CD  1 
ATOM   5440  O OE1 . GLN A 1 698 ? -2.292  4.963   40.106  1.00 106.18 ? 773  GLN A OE1 1 
ATOM   5441  N NE2 . GLN A 1 698 ? -2.173  6.051   38.144  1.00 79.08  ? 773  GLN A NE2 1 
ATOM   5442  N N   . HIS A 1 699 ? -4.340  10.396  41.910  1.00 119.70 ? 774  HIS A N   1 
ATOM   5443  C CA  . HIS A 1 699 ? -5.270  11.523  41.921  1.00 128.24 ? 774  HIS A CA  1 
ATOM   5444  C C   . HIS A 1 699 ? -4.650  12.735  42.605  1.00 120.66 ? 774  HIS A C   1 
ATOM   5445  O O   . HIS A 1 699 ? -4.732  13.861  42.100  1.00 112.66 ? 774  HIS A O   1 
ATOM   5446  C CB  . HIS A 1 699 ? -6.575  11.136  42.617  1.00 137.87 ? 774  HIS A CB  1 
ATOM   5447  C CG  . HIS A 1 699 ? -7.169  9.853   42.130  1.00 163.99 ? 774  HIS A CG  1 
ATOM   5448  N ND1 . HIS A 1 699 ? -6.952  9.365   40.859  1.00 202.04 ? 774  HIS A ND1 1 
ATOM   5449  C CD2 . HIS A 1 699 ? -7.978  8.957   42.744  1.00 202.54 ? 774  HIS A CD2 1 
ATOM   5450  C CE1 . HIS A 1 699 ? -7.600  8.223   40.712  1.00 214.36 ? 774  HIS A CE1 1 
ATOM   5451  N NE2 . HIS A 1 699 ? -8.230  7.953   41.841  1.00 220.27 ? 774  HIS A NE2 1 
ATOM   5452  N N   . TYR A 1 700 ? -4.023  12.520  43.764  1.00 109.85 ? 775  TYR A N   1 
ATOM   5453  C CA  . TYR A 1 700 ? -3.396  13.619  44.489  1.00 99.46  ? 775  TYR A CA  1 
ATOM   5454  C C   . TYR A 1 700 ? -2.117  14.104  43.822  1.00 98.32  ? 775  TYR A C   1 
ATOM   5455  O O   . TYR A 1 700 ? -1.612  15.172  44.186  1.00 105.51 ? 775  TYR A O   1 
ATOM   5456  C CB  . TYR A 1 700 ? -3.111  13.193  45.927  1.00 96.90  ? 775  TYR A CB  1 
ATOM   5457  C CG  . TYR A 1 700 ? -4.343  13.229  46.793  1.00 90.30  ? 775  TYR A CG  1 
ATOM   5458  C CD1 . TYR A 1 700 ? -5.098  14.387  46.909  1.00 87.56  ? 775  TYR A CD1 1 
ATOM   5459  C CD2 . TYR A 1 700 ? -4.771  12.094  47.466  1.00 94.12  ? 775  TYR A CD2 1 
ATOM   5460  C CE1 . TYR A 1 700 ? -6.234  14.421  47.694  1.00 95.84  ? 775  TYR A CE1 1 
ATOM   5461  C CE2 . TYR A 1 700 ? -5.906  12.117  48.250  1.00 90.76  ? 775  TYR A CE2 1 
ATOM   5462  C CZ  . TYR A 1 700 ? -6.634  13.282  48.361  1.00 94.60  ? 775  TYR A CZ  1 
ATOM   5463  O OH  . TYR A 1 700 ? -7.765  13.306  49.143  1.00 95.20  ? 775  TYR A OH  1 
ATOM   5464  N N   . LEU A 1 701 ? -1.581  13.340  42.868  1.00 95.93  ? 776  LEU A N   1 
ATOM   5465  C CA  . LEU A 1 701 ? -0.452  13.809  42.074  1.00 98.02  ? 776  LEU A CA  1 
ATOM   5466  C C   . LEU A 1 701 ? -0.857  14.998  41.215  1.00 106.18 ? 776  LEU A C   1 
ATOM   5467  O O   . LEU A 1 701 ? -0.066  15.924  41.002  1.00 82.57  ? 776  LEU A O   1 
ATOM   5468  C CB  . LEU A 1 701 ? 0.073   12.665  41.206  1.00 77.90  ? 776  LEU A CB  1 
ATOM   5469  C CG  . LEU A 1 701 ? 1.559   12.612  40.866  1.00 75.12  ? 776  LEU A CG  1 
ATOM   5470  C CD1 . LEU A 1 701 ? 2.345   12.451  42.139  1.00 82.40  ? 776  LEU A CD1 1 
ATOM   5471  C CD2 . LEU A 1 701 ? 1.842   11.450  39.935  1.00 68.55  ? 776  LEU A CD2 1 
ATOM   5472  N N   . THR A 1 702 ? -2.090  14.985  40.713  1.00 110.80 ? 777  THR A N   1 
ATOM   5473  C CA  . THR A 1 702 ? -2.642  16.102  39.955  1.00 95.93  ? 777  THR A CA  1 
ATOM   5474  C C   . THR A 1 702 ? -3.460  16.988  40.894  1.00 103.11 ? 777  THR A C   1 
ATOM   5475  O O   . THR A 1 702 ? -4.691  17.020  40.870  1.00 122.83 ? 777  THR A O   1 
ATOM   5476  C CB  . THR A 1 702 ? -3.478  15.585  38.788  1.00 92.11  ? 777  THR A CB  1 
ATOM   5477  O OG1 . THR A 1 702 ? -4.352  14.548  39.252  1.00 97.41  ? 777  THR A OG1 1 
ATOM   5478  C CG2 . THR A 1 702 ? -2.578  15.024  37.697  1.00 99.10  ? 777  THR A CG2 1 
ATOM   5479  N N   . ASN A 1 703 ? -2.737  17.708  41.746  1.00 87.47  ? 778  ASN A N   1 
ATOM   5480  C CA  . ASN A 1 703 ? -3.335  18.561  42.760  1.00 87.95  ? 778  ASN A CA  1 
ATOM   5481  C C   . ASN A 1 703 ? -2.776  19.969  42.617  1.00 94.71  ? 778  ASN A C   1 
ATOM   5482  O O   . ASN A 1 703 ? -1.700  20.174  42.051  1.00 104.08 ? 778  ASN A O   1 
ATOM   5483  C CB  . ASN A 1 703 ? -3.068  18.017  44.173  1.00 93.04  ? 778  ASN A CB  1 
ATOM   5484  C CG  . ASN A 1 703 ? -3.870  18.732  45.240  1.00 93.20  ? 778  ASN A CG  1 
ATOM   5485  O OD1 . ASN A 1 703 ? -3.538  19.847  45.642  1.00 88.79  ? 778  ASN A OD1 1 
ATOM   5486  N ND2 . ASN A 1 703 ? -4.930  18.086  45.712  1.00 97.18  ? 778  ASN A ND2 1 
ATOM   5487  N N   . VAL A 1 704 ? -3.522  20.947  43.135  1.00 97.50  ? 779  VAL A N   1 
ATOM   5488  C CA  . VAL A 1 704 ? -3.076  22.333  43.039  1.00 103.39 ? 779  VAL A CA  1 
ATOM   5489  C C   . VAL A 1 704 ? -1.957  22.607  44.037  1.00 109.09 ? 779  VAL A C   1 
ATOM   5490  O O   . VAL A 1 704 ? -0.985  23.305  43.723  1.00 119.64 ? 779  VAL A O   1 
ATOM   5491  C CB  . VAL A 1 704 ? -4.264  23.296  43.230  1.00 108.04 ? 779  VAL A CB  1 
ATOM   5492  C CG1 . VAL A 1 704 ? -4.991  23.012  44.537  1.00 129.22 ? 779  VAL A CG1 1 
ATOM   5493  C CG2 . VAL A 1 704 ? -3.791  24.741  43.176  1.00 102.32 ? 779  VAL A CG2 1 
ATOM   5494  N N   . ASN A 1 705 ? -2.063  22.055  45.244  1.00 102.87 ? 780  ASN A N   1 
ATOM   5495  C CA  . ASN A 1 705 ? -1.035  22.243  46.260  1.00 101.20 ? 780  ASN A CA  1 
ATOM   5496  C C   . ASN A 1 705 ? 0.165   21.362  45.935  1.00 107.72 ? 780  ASN A C   1 
ATOM   5497  O O   . ASN A 1 705 ? 0.037   20.136  45.845  1.00 99.22  ? 780  ASN A O   1 
ATOM   5498  C CB  . ASN A 1 705 ? -1.579  21.918  47.648  1.00 103.30 ? 780  ASN A CB  1 
ATOM   5499  C CG  . ASN A 1 705 ? -0.583  22.231  48.748  1.00 112.80 ? 780  ASN A CG  1 
ATOM   5500  O OD1 . ASN A 1 705 ? -0.647  21.666  49.841  1.00 120.28 ? 780  ASN A OD1 1 
ATOM   5501  N ND2 . ASN A 1 705 ? 0.345   23.138  48.465  1.00 116.78 ? 780  ASN A ND2 1 
ATOM   5502  N N   . THR A 1 706 ? 1.333   21.988  45.773  1.00 112.96 ? 781  THR A N   1 
ATOM   5503  C CA  . THR A 1 706 ? 2.529   21.238  45.403  1.00 106.03 ? 781  THR A CA  1 
ATOM   5504  C C   . THR A 1 706 ? 2.952   20.263  46.491  1.00 105.65 ? 781  THR A C   1 
ATOM   5505  O O   . THR A 1 706 ? 3.490   19.196  46.182  1.00 109.18 ? 781  THR A O   1 
ATOM   5506  C CB  . THR A 1 706 ? 3.676   22.195  45.084  1.00 98.96  ? 781  THR A CB  1 
ATOM   5507  O OG1 . THR A 1 706 ? 4.259   22.666  46.304  1.00 114.54 ? 781  THR A OG1 1 
ATOM   5508  C CG2 . THR A 1 706 ? 3.175   23.381  44.270  1.00 94.72  ? 781  THR A CG2 1 
ATOM   5509  N N   . THR A 1 707 ? 2.723   20.605  47.761  1.00 98.51  ? 782  THR A N   1 
ATOM   5510  C CA  . THR A 1 707 ? 3.132   19.717  48.844  1.00 95.19  ? 782  THR A CA  1 
ATOM   5511  C C   . THR A 1 707 ? 2.348   18.410  48.814  1.00 93.51  ? 782  THR A C   1 
ATOM   5512  O O   . THR A 1 707 ? 2.896   17.342  49.113  1.00 96.12  ? 782  THR A O   1 
ATOM   5513  C CB  . THR A 1 707 ? 2.963   20.418  50.191  1.00 81.86  ? 782  THR A CB  1 
ATOM   5514  O OG1 . THR A 1 707 ? 1.608   20.284  50.638  1.00 115.15 ? 782  THR A OG1 1 
ATOM   5515  C CG2 . THR A 1 707 ? 3.312   21.894  50.070  1.00 68.96  ? 782  THR A CG2 1 
ATOM   5516  N N   . VAL A 1 708 ? 1.067   18.474  48.445  1.00 81.57  ? 783  VAL A N   1 
ATOM   5517  C CA  . VAL A 1 708 ? 0.260   17.260  48.348  1.00 94.99  ? 783  VAL A CA  1 
ATOM   5518  C C   . VAL A 1 708 ? 0.787   16.362  47.235  1.00 93.46  ? 783  VAL A C   1 
ATOM   5519  O O   . VAL A 1 708 ? 0.942   15.145  47.413  1.00 101.23 ? 783  VAL A O   1 
ATOM   5520  C CB  . VAL A 1 708 ? -1.222  17.620  48.138  1.00 104.09 ? 783  VAL A CB  1 
ATOM   5521  C CG1 . VAL A 1 708 ? -2.022  16.391  47.732  1.00 81.17  ? 783  VAL A CG1 1 
ATOM   5522  C CG2 . VAL A 1 708 ? -1.798  18.247  49.400  1.00 100.67 ? 783  VAL A CG2 1 
ATOM   5523  N N   . LYS A 1 709 ? 1.065   16.951  46.067  1.00 81.46  ? 784  LYS A N   1 
ATOM   5524  C CA  . LYS A 1 709 ? 1.656   16.186  44.975  1.00 88.30  ? 784  LYS A CA  1 
ATOM   5525  C C   . LYS A 1 709 ? 2.994   15.587  45.384  1.00 85.79  ? 784  LYS A C   1 
ATOM   5526  O O   . LYS A 1 709 ? 3.302   14.447  45.026  1.00 77.98  ? 784  LYS A O   1 
ATOM   5527  C CB  . LYS A 1 709 ? 1.836   17.065  43.737  1.00 94.52  ? 784  LYS A CB  1 
ATOM   5528  C CG  . LYS A 1 709 ? 0.739   18.079  43.477  1.00 104.46 ? 784  LYS A CG  1 
ATOM   5529  C CD  . LYS A 1 709 ? 1.302   19.248  42.682  1.00 93.46  ? 784  LYS A CD  1 
ATOM   5530  C CE  . LYS A 1 709 ? 1.488   18.894  41.215  1.00 89.73  ? 784  LYS A CE  1 
ATOM   5531  N NZ  . LYS A 1 709 ? 1.050   20.000  40.321  1.00 97.69  ? 784  LYS A NZ  1 
ATOM   5532  N N   . GLU A 1 710 ? 3.805   16.344  46.128  1.00 86.99  ? 785  GLU A N   1 
ATOM   5533  C CA  . GLU A 1 710 ? 5.109   15.849  46.561  1.00 81.07  ? 785  GLU A CA  1 
ATOM   5534  C C   . GLU A 1 710 ? 4.960   14.643  47.477  1.00 87.49  ? 785  GLU A C   1 
ATOM   5535  O O   . GLU A 1 710 ? 5.661   13.636  47.318  1.00 91.70  ? 785  GLU A O   1 
ATOM   5536  C CB  . GLU A 1 710 ? 5.888   16.957  47.269  1.00 78.12  ? 785  GLU A CB  1 
ATOM   5537  C CG  . GLU A 1 710 ? 6.386   18.065  46.363  1.00 87.82  ? 785  GLU A CG  1 
ATOM   5538  C CD  . GLU A 1 710 ? 6.829   19.287  47.141  1.00 104.65 ? 785  GLU A CD  1 
ATOM   5539  O OE1 . GLU A 1 710 ? 7.829   19.193  47.884  1.00 91.42  ? 785  GLU A OE1 1 
ATOM   5540  O OE2 . GLU A 1 710 ? 6.174   20.343  47.011  1.00 115.07 ? 785  GLU A OE2 1 
ATOM   5541  N N   . GLN A 1 711 ? 4.060   14.737  48.457  1.00 80.45  ? 786  GLN A N   1 
ATOM   5542  C CA  . GLN A 1 711 ? 3.837   13.617  49.365  1.00 85.15  ? 786  GLN A CA  1 
ATOM   5543  C C   . GLN A 1 711 ? 3.355   12.387  48.602  1.00 86.86  ? 786  GLN A C   1 
ATOM   5544  O O   . GLN A 1 711 ? 3.862   11.273  48.802  1.00 82.52  ? 786  GLN A O   1 
ATOM   5545  C CB  . GLN A 1 711 ? 2.831   14.016  50.446  1.00 81.44  ? 786  GLN A CB  1 
ATOM   5546  C CG  . GLN A 1 711 ? 2.676   12.994  51.556  1.00 80.46  ? 786  GLN A CG  1 
ATOM   5547  C CD  . GLN A 1 711 ? 3.950   12.828  52.358  1.00 85.68  ? 786  GLN A CD  1 
ATOM   5548  O OE1 . GLN A 1 711 ? 4.351   13.728  53.097  1.00 79.79  ? 786  GLN A OE1 1 
ATOM   5549  N NE2 . GLN A 1 711 ? 4.601   11.680  52.208  1.00 88.78  ? 786  GLN A NE2 1 
ATOM   5550  N N   . ALA A 1 712 ? 2.381   12.580  47.706  1.00 83.89  ? 787  ALA A N   1 
ATOM   5551  C CA  . ALA A 1 712 ? 1.855   11.464  46.926  1.00 83.03  ? 787  ALA A CA  1 
ATOM   5552  C C   . ALA A 1 712 ? 2.935   10.838  46.053  1.00 83.68  ? 787  ALA A C   1 
ATOM   5553  O O   . ALA A 1 712 ? 3.049   9.612   45.985  1.00 82.53  ? 787  ALA A O   1 
ATOM   5554  C CB  . ALA A 1 712 ? 0.679   11.931  46.071  1.00 81.89  ? 787  ALA A CB  1 
ATOM   5555  N N   . PHE A 1 713 ? 3.755   11.666  45.400  1.00 76.73  ? 788  PHE A N   1 
ATOM   5556  C CA  . PHE A 1 713 ? 4.806   11.168  44.516  1.00 84.62  ? 788  PHE A CA  1 
ATOM   5557  C C   . PHE A 1 713 ? 5.861   10.393  45.293  1.00 78.77  ? 788  PHE A C   1 
ATOM   5558  O O   . PHE A 1 713 ? 6.292   9.312   44.874  1.00 77.62  ? 788  PHE A O   1 
ATOM   5559  C CB  . PHE A 1 713 ? 5.440   12.347  43.771  1.00 85.95  ? 788  PHE A CB  1 
ATOM   5560  C CG  . PHE A 1 713 ? 6.694   12.000  43.021  1.00 75.38  ? 788  PHE A CG  1 
ATOM   5561  C CD1 . PHE A 1 713 ? 6.632   11.410  41.772  1.00 77.35  ? 788  PHE A CD1 1 
ATOM   5562  C CD2 . PHE A 1 713 ? 7.938   12.277  43.564  1.00 77.01  ? 788  PHE A CD2 1 
ATOM   5563  C CE1 . PHE A 1 713 ? 7.787   11.097  41.080  1.00 82.59  ? 788  PHE A CE1 1 
ATOM   5564  C CE2 . PHE A 1 713 ? 9.093   11.965  42.879  1.00 80.35  ? 788  PHE A CE2 1 
ATOM   5565  C CZ  . PHE A 1 713 ? 9.019   11.375  41.637  1.00 74.62  ? 788  PHE A CZ  1 
ATOM   5566  N N   . THR A 1 714 ? 6.310   10.951  46.420  1.00 75.66  ? 789  THR A N   1 
ATOM   5567  C CA  . THR A 1 714 ? 7.278   10.273  47.274  1.00 61.86  ? 789  THR A CA  1 
ATOM   5568  C C   . THR A 1 714 ? 6.765   8.903   47.705  1.00 70.87  ? 789  THR A C   1 
ATOM   5569  O O   . THR A 1 714 ? 7.427   7.872   47.490  1.00 69.52  ? 789  THR A O   1 
ATOM   5570  C CB  . THR A 1 714 ? 7.571   11.157  48.490  1.00 59.92  ? 789  THR A CB  1 
ATOM   5571  O OG1 . THR A 1 714 ? 8.295   12.322  48.076  1.00 72.20  ? 789  THR A OG1 1 
ATOM   5572  C CG2 . THR A 1 714 ? 8.364   10.404  49.543  1.00 74.91  ? 789  THR A CG2 1 
ATOM   5573  N N   . ILE A 1 715 ? 5.573   8.877   48.311  1.00 77.06  ? 790  ILE A N   1 
ATOM   5574  C CA  . ILE A 1 715 ? 5.008   7.620   48.786  1.00 70.46  ? 790  ILE A CA  1 
ATOM   5575  C C   . ILE A 1 715 ? 4.794   6.661   47.624  1.00 72.99  ? 790  ILE A C   1 
ATOM   5576  O O   . ILE A 1 715 ? 4.967   5.447   47.764  1.00 74.41  ? 790  ILE A O   1 
ATOM   5577  C CB  . ILE A 1 715 ? 3.699   7.883   49.554  1.00 68.67  ? 790  ILE A CB  1 
ATOM   5578  C CG1 . ILE A 1 715 ? 3.990   8.531   50.907  1.00 71.32  ? 790  ILE A CG1 1 
ATOM   5579  C CG2 . ILE A 1 715 ? 2.934   6.594   49.761  1.00 69.43  ? 790  ILE A CG2 1 
ATOM   5580  C CD1 . ILE A 1 715 ? 2.746   9.020   51.617  1.00 78.55  ? 790  ILE A CD1 1 
ATOM   5581  N N   . LEU A 1 716 ? 4.446   7.193   46.450  1.00 69.98  ? 791  LEU A N   1 
ATOM   5582  C CA  . LEU A 1 716 ? 4.155   6.349   45.299  1.00 72.62  ? 791  LEU A CA  1 
ATOM   5583  C C   . LEU A 1 716 ? 5.414   5.673   44.780  1.00 75.82  ? 791  LEU A C   1 
ATOM   5584  O O   . LEU A 1 716 ? 5.393   4.484   44.444  1.00 79.14  ? 791  LEU A O   1 
ATOM   5585  C CB  . LEU A 1 716 ? 3.501   7.192   44.203  1.00 59.22  ? 791  LEU A CB  1 
ATOM   5586  C CG  . LEU A 1 716 ? 2.576   6.510   43.198  1.00 61.67  ? 791  LEU A CG  1 
ATOM   5587  C CD1 . LEU A 1 716 ? 1.770   5.410   43.866  1.00 65.88  ? 791  LEU A CD1 1 
ATOM   5588  C CD2 . LEU A 1 716 ? 1.663   7.544   42.560  1.00 62.21  ? 791  LEU A CD2 1 
ATOM   5589  N N   . CYS A 1 717 ? 6.519   6.416   44.703  1.00 70.39  ? 792  CYS A N   1 
ATOM   5590  C CA  . CYS A 1 717 ? 7.784   5.812   44.297  1.00 57.51  ? 792  CYS A CA  1 
ATOM   5591  C C   . CYS A 1 717 ? 8.210   4.735   45.286  1.00 67.53  ? 792  CYS A C   1 
ATOM   5592  O O   . CYS A 1 717 ? 8.613   3.631   44.890  1.00 83.78  ? 792  CYS A O   1 
ATOM   5593  C CB  . CYS A 1 717 ? 8.862   6.888   44.164  1.00 60.74  ? 792  CYS A CB  1 
ATOM   5594  S SG  . CYS A 1 717 ? 8.506   8.149   42.920  1.00 71.67  ? 792  CYS A SG  1 
ATOM   5595  N N   . ASP A 1 718 ? 8.113   5.032   46.587  1.00 66.99  ? 793  ASP A N   1 
ATOM   5596  C CA  . ASP A 1 718 ? 8.494   4.026   47.578  1.00 64.37  ? 793  ASP A CA  1 
ATOM   5597  C C   . ASP A 1 718 ? 7.601   2.790   47.498  1.00 77.19  ? 793  ASP A C   1 
ATOM   5598  O O   . ASP A 1 718 ? 8.090   1.659   47.597  1.00 77.87  ? 793  ASP A O   1 
ATOM   5599  C CB  . ASP A 1 718 ? 8.478   4.625   48.983  1.00 62.76  ? 793  ASP A CB  1 
ATOM   5600  C CG  . ASP A 1 718 ? 9.590   5.632   49.191  1.00 71.33  ? 793  ASP A CG  1 
ATOM   5601  O OD1 . ASP A 1 718 ? 10.419  5.793   48.273  1.00 76.09  ? 793  ASP A OD1 1 
ATOM   5602  O OD2 . ASP A 1 718 ? 9.646   6.251   50.274  1.00 69.32  ? 793  ASP A OD2 1 
ATOM   5603  N N   . ILE A 1 719 ? 6.293   2.984   47.312  1.00 79.64  ? 794  ILE A N   1 
ATOM   5604  C CA  . ILE A 1 719 ? 5.372   1.857   47.160  1.00 77.51  ? 794  ILE A CA  1 
ATOM   5605  C C   . ILE A 1 719 ? 5.745   1.022   45.943  1.00 74.90  ? 794  ILE A C   1 
ATOM   5606  O O   . ILE A 1 719 ? 5.838   -0.209  46.018  1.00 79.01  ? 794  ILE A O   1 
ATOM   5607  C CB  . ILE A 1 719 ? 3.919   2.360   47.067  1.00 77.93  ? 794  ILE A CB  1 
ATOM   5608  C CG1 . ILE A 1 719 ? 3.415   2.842   48.432  1.00 75.23  ? 794  ILE A CG1 1 
ATOM   5609  C CG2 . ILE A 1 719 ? 3.014   1.284   46.477  1.00 86.67  ? 794  ILE A CG2 1 
ATOM   5610  C CD1 . ILE A 1 719 ? 3.057   1.723   49.386  1.00 78.40  ? 794  ILE A CD1 1 
ATOM   5611  N N   . LEU A 1 720 ? 5.960   1.685   44.803  1.00 76.10  ? 795  LEU A N   1 
ATOM   5612  C CA  . LEU A 1 720 ? 6.274   0.972   43.571  1.00 81.25  ? 795  LEU A CA  1 
ATOM   5613  C C   . LEU A 1 720 ? 7.540   0.143   43.724  1.00 87.04  ? 795  LEU A C   1 
ATOM   5614  O O   . LEU A 1 720 ? 7.616   -0.985  43.222  1.00 91.03  ? 795  LEU A O   1 
ATOM   5615  C CB  . LEU A 1 720 ? 6.413   1.967   42.419  1.00 67.08  ? 795  LEU A CB  1 
ATOM   5616  C CG  . LEU A 1 720 ? 5.103   2.498   41.834  1.00 54.68  ? 795  LEU A CG  1 
ATOM   5617  C CD1 . LEU A 1 720 ? 5.360   3.694   40.928  1.00 64.77  ? 795  LEU A CD1 1 
ATOM   5618  C CD2 . LEU A 1 720 ? 4.369   1.403   41.086  1.00 69.57  ? 795  LEU A CD2 1 
ATOM   5619  N N   . MET A 1 721 ? 8.542   0.678   44.425  1.00 81.90  ? 796  MET A N   1 
ATOM   5620  C CA  . MET A 1 721 ? 9.760   -0.097  44.636  1.00 87.22  ? 796  MET A CA  1 
ATOM   5621  C C   . MET A 1 721 ? 9.520   -1.257  45.597  1.00 81.68  ? 796  MET A C   1 
ATOM   5622  O O   . MET A 1 721 ? 9.971   -2.381  45.346  1.00 83.92  ? 796  MET A O   1 
ATOM   5623  C CB  . MET A 1 721 ? 10.881  0.805   45.146  1.00 81.75  ? 796  MET A CB  1 
ATOM   5624  C CG  . MET A 1 721 ? 12.207  0.088   45.270  1.00 79.64  ? 796  MET A CG  1 
ATOM   5625  S SD  . MET A 1 721 ? 12.793  -0.415  43.643  1.00 78.13  ? 796  MET A SD  1 
ATOM   5626  C CE  . MET A 1 721 ? 13.085  1.180   42.882  1.00 73.72  ? 796  MET A CE  1 
ATOM   5627  N N   . ILE A 1 722 ? 8.797   -1.006  46.692  1.00 83.93  ? 797  ILE A N   1 
ATOM   5628  C CA  . ILE A 1 722 ? 8.541   -2.044  47.687  1.00 85.70  ? 797  ILE A CA  1 
ATOM   5629  C C   . ILE A 1 722 ? 7.693   -3.163  47.096  1.00 87.44  ? 797  ILE A C   1 
ATOM   5630  O O   . ILE A 1 722 ? 7.861   -4.338  47.450  1.00 82.77  ? 797  ILE A O   1 
ATOM   5631  C CB  . ILE A 1 722 ? 7.876   -1.416  48.930  1.00 79.27  ? 797  ILE A CB  1 
ATOM   5632  C CG1 . ILE A 1 722 ? 8.905   -0.615  49.728  1.00 82.61  ? 797  ILE A CG1 1 
ATOM   5633  C CG2 . ILE A 1 722 ? 7.240   -2.476  49.811  1.00 81.73  ? 797  ILE A CG2 1 
ATOM   5634  C CD1 . ILE A 1 722 ? 8.297   0.449   50.608  1.00 75.90  ? 797  ILE A CD1 1 
ATOM   5635  N N   . PHE A 1 723 ? 6.784   -2.827  46.182  1.00 91.72  ? 798  PHE A N   1 
ATOM   5636  C CA  . PHE A 1 723 ? 5.877   -3.788  45.570  1.00 89.49  ? 798  PHE A CA  1 
ATOM   5637  C C   . PHE A 1 723 ? 6.248   -4.087  44.120  1.00 90.28  ? 798  PHE A C   1 
ATOM   5638  O O   . PHE A 1 723 ? 5.388   -4.456  43.317  1.00 108.64 ? 798  PHE A O   1 
ATOM   5639  C CB  . PHE A 1 723 ? 4.437   -3.288  45.665  1.00 88.40  ? 798  PHE A CB  1 
ATOM   5640  C CG  . PHE A 1 723 ? 3.834   -3.440  47.030  1.00 76.10  ? 798  PHE A CG  1 
ATOM   5641  C CD1 . PHE A 1 723 ? 3.385   -4.675  47.465  1.00 77.74  ? 798  PHE A CD1 1 
ATOM   5642  C CD2 . PHE A 1 723 ? 3.736   -2.356  47.887  1.00 72.78  ? 798  PHE A CD2 1 
ATOM   5643  C CE1 . PHE A 1 723 ? 2.837   -4.827  48.722  1.00 83.72  ? 798  PHE A CE1 1 
ATOM   5644  C CE2 . PHE A 1 723 ? 3.188   -2.501  49.147  1.00 79.13  ? 798  PHE A CE2 1 
ATOM   5645  C CZ  . PHE A 1 723 ? 2.738   -3.739  49.565  1.00 86.70  ? 798  PHE A CZ  1 
ATOM   5646  N N   . SER A 1 724 ? 7.522   -3.930  43.771  1.00 93.53  ? 799  SER A N   1 
ATOM   5647  C CA  . SER A 1 724 ? 7.982   -4.256  42.430  1.00 100.19 ? 799  SER A CA  1 
ATOM   5648  C C   . SER A 1 724 ? 8.132   -5.769  42.286  1.00 106.26 ? 799  SER A C   1 
ATOM   5649  O O   . SER A 1 724 ? 7.814   -6.541  43.195  1.00 107.41 ? 799  SER A O   1 
ATOM   5650  C CB  . SER A 1 724 ? 9.296   -3.538  42.130  1.00 96.54  ? 799  SER A CB  1 
ATOM   5651  O OG  . SER A 1 724 ? 10.303  -3.906  43.056  1.00 101.67 ? 799  SER A OG  1 
ATOM   5652  N N   . HIS A 1 725 ? 8.615   -6.199  41.117  1.00 96.59  ? 800  HIS A N   1 
ATOM   5653  C CA  . HIS A 1 725 ? 8.885   -7.616  40.895  1.00 99.90  ? 800  HIS A CA  1 
ATOM   5654  C C   . HIS A 1 725 ? 9.789   -8.187  41.981  1.00 103.94 ? 800  HIS A C   1 
ATOM   5655  O O   . HIS A 1 725 ? 9.565   -9.302  42.472  1.00 102.79 ? 800  HIS A O   1 
ATOM   5656  C CB  . HIS A 1 725 ? 9.506   -7.806  39.512  1.00 104.81 ? 800  HIS A CB  1 
ATOM   5657  C CG  . HIS A 1 725 ? 10.333  -6.641  39.063  1.00 124.81 ? 800  HIS A CG  1 
ATOM   5658  N ND1 . HIS A 1 725 ? 11.505  -6.272  39.690  1.00 123.93 ? 800  HIS A ND1 1 
ATOM   5659  C CD2 . HIS A 1 725 ? 10.146  -5.748  38.062  1.00 130.84 ? 800  HIS A CD2 1 
ATOM   5660  C CE1 . HIS A 1 725 ? 12.009  -5.210  39.087  1.00 120.10 ? 800  HIS A CE1 1 
ATOM   5661  N NE2 . HIS A 1 725 ? 11.203  -4.872  38.097  1.00 119.27 ? 800  HIS A NE2 1 
ATOM   5662  N N   . GLN A 1 726 ? 10.792  -7.410  42.401  1.00 101.55 ? 801  GLN A N   1 
ATOM   5663  C CA  . GLN A 1 726 ? 11.730  -7.832  43.434  1.00 108.91 ? 801  GLN A CA  1 
ATOM   5664  C C   . GLN A 1 726 ? 11.048  -8.247  44.732  1.00 110.19 ? 801  GLN A C   1 
ATOM   5665  O O   . GLN A 1 726 ? 11.711  -8.832  45.595  1.00 118.39 ? 801  GLN A O   1 
ATOM   5666  C CB  . GLN A 1 726 ? 12.723  -6.707  43.722  1.00 108.75 ? 801  GLN A CB  1 
ATOM   5667  C CG  . GLN A 1 726 ? 13.329  -6.082  42.478  1.00 110.07 ? 801  GLN A CG  1 
ATOM   5668  C CD  . GLN A 1 726 ? 14.424  -6.929  41.864  1.00 129.52 ? 801  GLN A CD  1 
ATOM   5669  O OE1 . GLN A 1 726 ? 14.709  -8.034  42.326  1.00 135.46 ? 801  GLN A OE1 1 
ATOM   5670  N NE2 . GLN A 1 726 ? 15.046  -6.413  40.810  1.00 135.47 ? 801  GLN A NE2 1 
ATOM   5671  N N   . ILE A 1 727 ? 9.753   -7.959  44.896  1.00 111.81 ? 802  ILE A N   1 
ATOM   5672  C CA  . ILE A 1 727 ? 9.042   -8.393  46.093  1.00 109.84 ? 802  ILE A CA  1 
ATOM   5673  C C   . ILE A 1 727 ? 8.994   -9.910  46.197  1.00 107.07 ? 802  ILE A C   1 
ATOM   5674  O O   . ILE A 1 727 ? 8.762   -10.443 47.287  1.00 112.94 ? 802  ILE A O   1 
ATOM   5675  C CB  . ILE A 1 727 ? 7.615   -7.802  46.139  1.00 97.45  ? 802  ILE A CB  1 
ATOM   5676  C CG1 . ILE A 1 727 ? 7.147   -7.662  47.592  1.00 94.72  ? 802  ILE A CG1 1 
ATOM   5677  C CG2 . ILE A 1 727 ? 6.644   -8.667  45.351  1.00 100.47 ? 802  ILE A CG2 1 
ATOM   5678  C CD1 . ILE A 1 727 ? 5.811   -6.970  47.754  1.00 98.12  ? 802  ILE A CD1 1 
ATOM   5679  N N   . MET A 1 728 ? 9.210   -10.630 45.095  1.00 112.88 ? 803  MET A N   1 
ATOM   5680  C CA  . MET A 1 728 ? 9.262   -12.085 45.148  1.00 120.22 ? 803  MET A CA  1 
ATOM   5681  C C   . MET A 1 728 ? 10.644  -12.635 44.832  1.00 119.90 ? 803  MET A C   1 
ATOM   5682  O O   . MET A 1 728 ? 10.820  -13.859 44.810  1.00 123.80 ? 803  MET A O   1 
ATOM   5683  C CB  . MET A 1 728 ? 8.240   -12.699 44.187  1.00 110.07 ? 803  MET A CB  1 
ATOM   5684  C CG  . MET A 1 728 ? 8.714   -12.769 42.751  1.00 123.06 ? 803  MET A CG  1 
ATOM   5685  S SD  . MET A 1 728 ? 7.356   -12.783 41.577  1.00 136.07 ? 803  MET A SD  1 
ATOM   5686  C CE  . MET A 1 728 ? 8.269   -12.809 40.041  1.00 125.43 ? 803  MET A CE  1 
ATOM   5687  N N   . SER A 1 729 ? 11.631  -11.762 44.611  1.00 115.27 ? 804  SER A N   1 
ATOM   5688  C CA  . SER A 1 729 ? 12.921  -12.195 44.082  1.00 118.77 ? 804  SER A CA  1 
ATOM   5689  C C   . SER A 1 729 ? 13.620  -13.177 45.015  1.00 122.84 ? 804  SER A C   1 
ATOM   5690  O O   . SER A 1 729 ? 14.197  -14.171 44.559  1.00 133.04 ? 804  SER A O   1 
ATOM   5691  C CB  . SER A 1 729 ? 13.809  -10.978 43.824  1.00 113.60 ? 804  SER A CB  1 
ATOM   5692  O OG  . SER A 1 729 ? 13.966  -10.205 45.001  1.00 117.26 ? 804  SER A OG  1 
ATOM   5693  N N   . GLY A 1 730 ? 13.587  -12.918 46.319  1.00 119.56 ? 805  GLY A N   1 
ATOM   5694  C CA  . GLY A 1 730 ? 14.309  -13.756 47.253  1.00 122.92 ? 805  GLY A CA  1 
ATOM   5695  C C   . GLY A 1 730 ? 13.441  -14.706 48.047  1.00 126.02 ? 805  GLY A C   1 
ATOM   5696  O O   . GLY A 1 730 ? 13.077  -14.412 49.190  1.00 141.97 ? 805  GLY A O   1 
ATOM   5697  N N   . GLY A 1 731 ? 13.102  -15.851 47.456  1.00 132.85 ? 806  GLY A N   1 
ATOM   5698  C CA  . GLY A 1 731 ? 12.326  -16.865 48.150  1.00 126.74 ? 806  GLY A CA  1 
ATOM   5699  C C   . GLY A 1 731 ? 10.993  -16.364 48.663  1.00 130.26 ? 806  GLY A C   1 
ATOM   5700  O O   . GLY A 1 731 ? 10.468  -16.879 49.655  1.00 130.23 ? 806  GLY A O   1 
ATOM   5701  N N   . ARG A 1 732 ? 10.439  -15.354 48.001  1.00 127.60 ? 807  ARG A N   1 
ATOM   5702  C CA  . ARG A 1 732 ? 9.163   -14.763 48.381  1.00 135.07 ? 807  ARG A CA  1 
ATOM   5703  C C   . ARG A 1 732 ? 8.122   -14.994 47.295  1.00 131.65 ? 807  ARG A C   1 
ATOM   5704  O O   . ARG A 1 732 ? 7.303   -14.123 46.994  1.00 127.51 ? 807  ARG A O   1 
ATOM   5705  C CB  . ARG A 1 732 ? 9.317   -13.272 48.672  1.00 131.45 ? 807  ARG A CB  1 
ATOM   5706  C CG  . ARG A 1 732 ? 9.873   -12.966 50.054  1.00 125.14 ? 807  ARG A CG  1 
ATOM   5707  C CD  . ARG A 1 732 ? 10.329  -11.520 50.173  1.00 106.41 ? 807  ARG A CD  1 
ATOM   5708  N NE  . ARG A 1 732 ? 10.892  -11.002 48.931  1.00 109.54 ? 807  ARG A NE  1 
ATOM   5709  C CZ  . ARG A 1 732 ? 12.186  -10.821 48.711  1.00 109.09 ? 807  ARG A CZ  1 
ATOM   5710  N NH1 . ARG A 1 732 ? 13.091  -11.114 49.629  1.00 111.76 ? 807  ARG A NH1 1 
ATOM   5711  N NH2 . ARG A 1 732 ? 12.581  -10.324 47.543  1.00 118.91 ? 807  ARG A NH2 1 
ATOM   5712  N N   . ASP A 1 733 ? 8.145   -16.189 46.696  1.00 131.77 ? 808  ASP A N   1 
ATOM   5713  C CA  . ASP A 1 733 ? 7.220   -16.512 45.615  1.00 132.63 ? 808  ASP A CA  1 
ATOM   5714  C C   . ASP A 1 733 ? 5.766   -16.469 46.063  1.00 125.91 ? 808  ASP A C   1 
ATOM   5715  O O   . ASP A 1 733 ? 4.871   -16.365 45.217  1.00 115.40 ? 808  ASP A O   1 
ATOM   5716  C CB  . ASP A 1 733 ? 7.553   -17.890 45.041  1.00 134.42 ? 808  ASP A CB  1 
ATOM   5717  C CG  . ASP A 1 733 ? 9.034   -18.062 44.771  1.00 135.70 ? 808  ASP A CG  1 
ATOM   5718  O OD1 . ASP A 1 733 ? 9.729   -18.655 45.623  1.00 128.16 ? 808  ASP A OD1 1 
ATOM   5719  O OD2 . ASP A 1 733 ? 9.503   -17.601 43.710  1.00 147.48 ? 808  ASP A OD2 1 
ATOM   5720  N N   . MET A 1 734 ? 5.509   -16.556 47.369  1.00 123.84 ? 809  MET A N   1 
ATOM   5721  C CA  . MET A 1 734 ? 4.156   -16.364 47.874  1.00 129.97 ? 809  MET A CA  1 
ATOM   5722  C C   . MET A 1 734 ? 3.696   -14.918 47.738  1.00 124.35 ? 809  MET A C   1 
ATOM   5723  O O   . MET A 1 734 ? 2.488   -14.662 47.738  1.00 122.72 ? 809  MET A O   1 
ATOM   5724  C CB  . MET A 1 734 ? 4.077   -16.815 49.335  1.00 129.61 ? 809  MET A CB  1 
ATOM   5725  C CG  . MET A 1 734 ? 4.533   -15.767 50.338  1.00 130.80 ? 809  MET A CG  1 
ATOM   5726  S SD  . MET A 1 734 ? 3.961   -16.109 52.014  1.00 156.04 ? 809  MET A SD  1 
ATOM   5727  C CE  . MET A 1 734 ? 2.676   -14.876 52.197  1.00 161.13 ? 809  MET A CE  1 
ATOM   5728  N N   . LEU A 1 735 ? 4.628   -13.974 47.617  1.00 123.83 ? 810  LEU A N   1 
ATOM   5729  C CA  . LEU A 1 735 ? 4.300   -12.571 47.404  1.00 119.38 ? 810  LEU A CA  1 
ATOM   5730  C C   . LEU A 1 735 ? 4.135   -12.223 45.931  1.00 118.92 ? 810  LEU A C   1 
ATOM   5731  O O   . LEU A 1 735 ? 3.903   -11.051 45.610  1.00 113.57 ? 810  LEU A O   1 
ATOM   5732  C CB  . LEU A 1 735 ? 5.378   -11.675 48.026  1.00 111.84 ? 810  LEU A CB  1 
ATOM   5733  C CG  . LEU A 1 735 ? 5.557   -11.747 49.544  1.00 102.89 ? 810  LEU A CG  1 
ATOM   5734  C CD1 . LEU A 1 735 ? 6.463   -10.627 50.033  1.00 93.81  ? 810  LEU A CD1 1 
ATOM   5735  C CD2 . LEU A 1 735 ? 4.211   -11.702 50.249  1.00 105.50 ? 810  LEU A CD2 1 
ATOM   5736  N N   . GLU A 1 736 ? 4.257   -13.204 45.037  1.00 125.22 ? 811  GLU A N   1 
ATOM   5737  C CA  . GLU A 1 736 ? 4.088   -12.953 43.607  1.00 119.22 ? 811  GLU A CA  1 
ATOM   5738  C C   . GLU A 1 736 ? 2.755   -12.297 43.261  1.00 107.19 ? 811  GLU A C   1 
ATOM   5739  O O   . GLU A 1 736 ? 2.748   -11.415 42.386  1.00 96.87  ? 811  GLU A O   1 
ATOM   5740  C CB  . GLU A 1 736 ? 4.268   -14.265 42.827  1.00 121.39 ? 811  GLU A CB  1 
ATOM   5741  C CG  . GLU A 1 736 ? 4.215   -14.127 41.306  1.00 115.04 ? 811  GLU A CG  1 
ATOM   5742  C CD  . GLU A 1 736 ? 2.807   -14.187 40.745  1.00 127.97 ? 811  GLU A CD  1 
ATOM   5743  O OE1 . GLU A 1 736 ? 1.991   -14.977 41.262  1.00 133.37 ? 811  GLU A OE1 1 
ATOM   5744  O OE2 . GLU A 1 736 ? 2.523   -13.445 39.781  1.00 128.44 ? 811  GLU A OE2 1 
ATOM   5745  N N   . PRO A 1 737 ? 1.617   -12.664 43.863  1.00 108.93 ? 812  PRO A N   1 
ATOM   5746  C CA  . PRO A 1 737 ? 0.390   -11.897 43.592  1.00 105.19 ? 812  PRO A CA  1 
ATOM   5747  C C   . PRO A 1 737 ? 0.507   -10.431 43.968  1.00 111.62 ? 812  PRO A C   1 
ATOM   5748  O O   . PRO A 1 737 ? -0.186  -9.589  43.383  1.00 114.50 ? 812  PRO A O   1 
ATOM   5749  C CB  . PRO A 1 737 ? -0.664  -12.612 44.448  1.00 103.91 ? 812  PRO A CB  1 
ATOM   5750  C CG  . PRO A 1 737 ? -0.163  -13.999 44.575  1.00 106.17 ? 812  PRO A CG  1 
ATOM   5751  C CD  . PRO A 1 737 ? 1.331   -13.886 44.640  1.00 107.37 ? 812  PRO A CD  1 
ATOM   5752  N N   . LEU A 1 738 ? 1.383   -10.100 44.915  1.00 116.67 ? 813  LEU A N   1 
ATOM   5753  C CA  . LEU A 1 738 ? 1.482   -8.750  45.468  1.00 108.52 ? 813  LEU A CA  1 
ATOM   5754  C C   . LEU A 1 738 ? 2.500   -7.911  44.692  1.00 102.09 ? 813  LEU A C   1 
ATOM   5755  O O   . LEU A 1 738 ? 3.474   -7.395  45.240  1.00 117.60 ? 813  LEU A O   1 
ATOM   5756  C CB  . LEU A 1 738 ? 1.847   -8.824  46.945  1.00 97.80  ? 813  LEU A CB  1 
ATOM   5757  C CG  . LEU A 1 738 ? 0.715   -8.873  47.968  1.00 98.06  ? 813  LEU A CG  1 
ATOM   5758  C CD1 . LEU A 1 738 ? 1.254   -9.344  49.304  1.00 99.87  ? 813  LEU A CD1 1 
ATOM   5759  C CD2 . LEU A 1 738 ? 0.079   -7.507  48.108  1.00 116.37 ? 813  LEU A CD2 1 
ATOM   5760  N N   . VAL A 1 739 ? 2.256   -7.770  43.392  1.00 94.12  ? 814  VAL A N   1 
ATOM   5761  C CA  . VAL A 1 739 ? 3.114   -6.969  42.528  1.00 90.48  ? 814  VAL A CA  1 
ATOM   5762  C C   . VAL A 1 739 ? 2.274   -5.877  41.886  1.00 96.78  ? 814  VAL A C   1 
ATOM   5763  O O   . VAL A 1 739 ? 1.084   -6.064  41.611  1.00 116.98 ? 814  VAL A O   1 
ATOM   5764  C CB  . VAL A 1 739 ? 3.814   -7.819  41.444  1.00 78.82  ? 814  VAL A CB  1 
ATOM   5765  C CG1 . VAL A 1 739 ? 4.970   -8.609  42.045  1.00 88.34  ? 814  VAL A CG1 1 
ATOM   5766  C CG2 . VAL A 1 739 ? 2.815   -8.732  40.747  1.00 113.46 ? 814  VAL A CG2 1 
ATOM   5767  N N   . TYR A 1 740 ? 2.902   -4.727  41.652  1.00 79.73  ? 815  TYR A N   1 
ATOM   5768  C CA  . TYR A 1 740 ? 2.255   -3.599  40.990  1.00 100.89 ? 815  TYR A CA  1 
ATOM   5769  C C   . TYR A 1 740 ? 3.164   -3.115  39.871  1.00 91.18  ? 815  TYR A C   1 
ATOM   5770  O O   . TYR A 1 740 ? 4.256   -2.599  40.131  1.00 92.91  ? 815  TYR A O   1 
ATOM   5771  C CB  . TYR A 1 740 ? 1.950   -2.470  41.978  1.00 93.82  ? 815  TYR A CB  1 
ATOM   5772  C CG  . TYR A 1 740 ? 1.000   -1.421  41.438  1.00 85.28  ? 815  TYR A CG  1 
ATOM   5773  C CD1 . TYR A 1 740 ? 1.430   -0.464  40.527  1.00 81.84  ? 815  TYR A CD1 1 
ATOM   5774  C CD2 . TYR A 1 740 ? -0.333  -1.404  41.824  1.00 91.48  ? 815  TYR A CD2 1 
ATOM   5775  C CE1 . TYR A 1 740 ? 0.562   0.491   40.028  1.00 94.55  ? 815  TYR A CE1 1 
ATOM   5776  C CE2 . TYR A 1 740 ? -1.208  -0.456  41.331  1.00 111.21 ? 815  TYR A CE2 1 
ATOM   5777  C CZ  . TYR A 1 740 ? -0.757  0.489   40.434  1.00 118.22 ? 815  TYR A CZ  1 
ATOM   5778  O OH  . TYR A 1 740 ? -1.628  1.433   39.941  1.00 113.89 ? 815  TYR A OH  1 
ATOM   5779  N N   . THR A 1 741 ? 2.715   -3.288  38.630  1.00 91.33  ? 816  THR A N   1 
ATOM   5780  C CA  . THR A 1 741 ? 3.435   -2.773  37.475  1.00 86.03  ? 816  THR A CA  1 
ATOM   5781  C C   . THR A 1 741 ? 2.932   -1.373  37.157  1.00 93.18  ? 816  THR A C   1 
ATOM   5782  O O   . THR A 1 741 ? 1.721   -1.193  36.965  1.00 104.14 ? 816  THR A O   1 
ATOM   5783  C CB  . THR A 1 741 ? 3.244   -3.679  36.270  1.00 100.55 ? 816  THR A CB  1 
ATOM   5784  O OG1 . THR A 1 741 ? 3.575   -5.026  36.628  1.00 113.76 ? 816  THR A OG1 1 
ATOM   5785  C CG2 . THR A 1 741 ? 4.134   -3.229  35.119  1.00 81.52  ? 816  THR A CG2 1 
ATOM   5786  N N   . PRO A 1 742 ? 3.800   -0.364  37.109  1.00 80.50  ? 817  PRO A N   1 
ATOM   5787  C CA  . PRO A 1 742 ? 3.334   1.001   36.820  1.00 91.84  ? 817  PRO A CA  1 
ATOM   5788  C C   . PRO A 1 742 ? 2.705   1.082   35.438  1.00 92.44  ? 817  PRO A C   1 
ATOM   5789  O O   . PRO A 1 742 ? 3.351   0.806   34.424  1.00 88.93  ? 817  PRO A O   1 
ATOM   5790  C CB  . PRO A 1 742 ? 4.612   1.844   36.910  1.00 90.46  ? 817  PRO A CB  1 
ATOM   5791  C CG  . PRO A 1 742 ? 5.597   1.014   37.655  1.00 94.58  ? 817  PRO A CG  1 
ATOM   5792  C CD  . PRO A 1 742 ? 5.236   -0.419  37.430  1.00 99.88  ? 817  PRO A CD  1 
ATOM   5793  N N   . ASP A 1 743 ? 1.427   1.447   35.405  1.00 105.84 ? 818  ASP A N   1 
ATOM   5794  C CA  . ASP A 1 743 ? 0.764   1.682   34.134  1.00 105.41 ? 818  ASP A CA  1 
ATOM   5795  C C   . ASP A 1 743 ? 1.398   2.880   33.431  1.00 93.27  ? 818  ASP A C   1 
ATOM   5796  O O   . ASP A 1 743 ? 2.068   3.714   34.048  1.00 96.20  ? 818  ASP A O   1 
ATOM   5797  C CB  . ASP A 1 743 ? -0.736  1.902   34.337  1.00 106.52 ? 818  ASP A CB  1 
ATOM   5798  C CG  . ASP A 1 743 ? -1.039  2.899   35.437  1.00 109.69 ? 818  ASP A CG  1 
ATOM   5799  O OD1 . ASP A 1 743 ? -0.913  2.533   36.625  1.00 106.86 ? 818  ASP A OD1 1 
ATOM   5800  O OD2 . ASP A 1 743 ? -1.412  4.046   35.114  1.00 112.66 ? 818  ASP A OD2 1 
ATOM   5801  N N   . SER A 1 744 ? 1.186   2.951   32.115  1.00 78.87  ? 819  SER A N   1 
ATOM   5802  C CA  . SER A 1 744 ? 1.833   3.993   31.323  1.00 87.92  ? 819  SER A CA  1 
ATOM   5803  C C   . SER A 1 744 ? 1.425   5.385   31.789  1.00 100.05 ? 819  SER A C   1 
ATOM   5804  O O   . SER A 1 744 ? 2.246   6.309   31.793  1.00 95.95  ? 819  SER A O   1 
ATOM   5805  C CB  . SER A 1 744 ? 1.504   3.804   29.846  1.00 97.18  ? 819  SER A CB  1 
ATOM   5806  O OG  . SER A 1 744 ? 0.104   3.719   29.644  1.00 127.23 ? 819  SER A OG  1 
ATOM   5807  N N   . SER A 1 745 ? 0.161   5.554   32.185  1.00 101.34 ? 820  SER A N   1 
ATOM   5808  C CA  . SER A 1 745 ? -0.274  6.838   32.726  1.00 101.14 ? 820  SER A CA  1 
ATOM   5809  C C   . SER A 1 745 ? 0.479   7.178   34.004  1.00 103.23 ? 820  SER A C   1 
ATOM   5810  O O   . SER A 1 745 ? 0.854   8.334   34.225  1.00 109.73 ? 820  SER A O   1 
ATOM   5811  C CB  . SER A 1 745 ? -1.779  6.820   32.987  1.00 110.76 ? 820  SER A CB  1 
ATOM   5812  O OG  . SER A 1 745 ? -2.171  5.618   33.628  1.00 121.57 ? 820  SER A OG  1 
ATOM   5813  N N   . LEU A 1 746 ? 0.708   6.178   34.858  1.00 93.73  ? 821  LEU A N   1 
ATOM   5814  C CA  . LEU A 1 746 ? 1.435   6.406   36.103  1.00 81.88  ? 821  LEU A CA  1 
ATOM   5815  C C   . LEU A 1 746 ? 2.876   6.817   35.828  1.00 86.76  ? 821  LEU A C   1 
ATOM   5816  O O   . LEU A 1 746 ? 3.386   7.772   36.427  1.00 81.05  ? 821  LEU A O   1 
ATOM   5817  C CB  . LEU A 1 746 ? 1.382   5.147   36.969  1.00 76.92  ? 821  LEU A CB  1 
ATOM   5818  C CG  . LEU A 1 746 ? 2.149   5.160   38.291  1.00 82.95  ? 821  LEU A CG  1 
ATOM   5819  C CD1 . LEU A 1 746 ? 1.864   6.429   39.073  1.00 72.30  ? 821  LEU A CD1 1 
ATOM   5820  C CD2 . LEU A 1 746 ? 1.800   3.930   39.116  1.00 73.33  ? 821  LEU A CD2 1 
ATOM   5821  N N   . GLN A 1 747 ? 3.550   6.094   34.931  1.00 88.36  ? 822  GLN A N   1 
ATOM   5822  C CA  . GLN A 1 747 ? 4.910   6.453   34.546  1.00 79.76  ? 822  GLN A CA  1 
ATOM   5823  C C   . GLN A 1 747 ? 4.959   7.862   33.973  1.00 84.26  ? 822  GLN A C   1 
ATOM   5824  O O   . GLN A 1 747 ? 5.867   8.645   34.289  1.00 83.01  ? 822  GLN A O   1 
ATOM   5825  C CB  . GLN A 1 747 ? 5.436   5.444   33.526  1.00 73.19  ? 822  GLN A CB  1 
ATOM   5826  C CG  . GLN A 1 747 ? 5.420   4.001   34.004  1.00 76.10  ? 822  GLN A CG  1 
ATOM   5827  C CD  . GLN A 1 747 ? 6.447   3.141   33.293  1.00 85.51  ? 822  GLN A CD  1 
ATOM   5828  O OE1 . GLN A 1 747 ? 7.273   3.643   32.530  1.00 85.26  ? 822  GLN A OE1 1 
ATOM   5829  N NE2 . GLN A 1 747 ? 6.393   1.836   33.530  1.00 83.45  ? 822  GLN A NE2 1 
ATOM   5830  N N   . SER A 1 748 ? 3.980   8.204   33.132  1.00 92.58  ? 823  SER A N   1 
ATOM   5831  C CA  . SER A 1 748 ? 3.938   9.530   32.530  1.00 99.13  ? 823  SER A CA  1 
ATOM   5832  C C   . SER A 1 748 ? 3.756   10.607  33.590  1.00 95.74  ? 823  SER A C   1 
ATOM   5833  O O   . SER A 1 748 ? 4.412   11.651  33.541  1.00 92.17  ? 823  SER A O   1 
ATOM   5834  C CB  . SER A 1 748 ? 2.808   9.597   31.504  1.00 101.86 ? 823  SER A CB  1 
ATOM   5835  O OG  . SER A 1 748 ? 2.775   8.436   30.694  1.00 111.74 ? 823  SER A OG  1 
ATOM   5836  N N   . GLU A 1 749 ? 2.871   10.366  34.562  1.00 90.51  ? 824  GLU A N   1 
ATOM   5837  C CA  . GLU A 1 749 ? 2.636   11.347  35.618  1.00 84.58  ? 824  GLU A CA  1 
ATOM   5838  C C   . GLU A 1 749 ? 3.863   11.509  36.507  1.00 83.02  ? 824  GLU A C   1 
ATOM   5839  O O   . GLU A 1 749 ? 4.174   12.622  36.947  1.00 79.68  ? 824  GLU A O   1 
ATOM   5840  C CB  . GLU A 1 749 ? 1.421   10.937  36.450  1.00 95.66  ? 824  GLU A CB  1 
ATOM   5841  C CG  . GLU A 1 749 ? 0.394   12.043  36.669  1.00 95.96  ? 824  GLU A CG  1 
ATOM   5842  C CD  . GLU A 1 749 ? -0.243  12.523  35.379  1.00 103.37 ? 824  GLU A CD  1 
ATOM   5843  O OE1 . GLU A 1 749 ? -0.847  11.692  34.670  1.00 126.48 ? 824  GLU A OE1 1 
ATOM   5844  O OE2 . GLU A 1 749 ? -0.149  13.732  35.081  1.00 105.20 ? 824  GLU A OE2 1 
ATOM   5845  N N   . LEU A 1 750 ? 4.578   10.414  36.777  1.00 84.60  ? 825  LEU A N   1 
ATOM   5846  C CA  . LEU A 1 750 ? 5.791   10.505  37.586  1.00 73.64  ? 825  LEU A CA  1 
ATOM   5847  C C   . LEU A 1 750 ? 6.869   11.305  36.861  1.00 79.88  ? 825  LEU A C   1 
ATOM   5848  O O   . LEU A 1 750 ? 7.500   12.202  37.441  1.00 87.19  ? 825  LEU A O   1 
ATOM   5849  C CB  . LEU A 1 750 ? 6.291   9.099   37.929  1.00 67.75  ? 825  LEU A CB  1 
ATOM   5850  C CG  . LEU A 1 750 ? 5.353   8.212   38.759  1.00 58.64  ? 825  LEU A CG  1 
ATOM   5851  C CD1 . LEU A 1 750 ? 5.878   6.786   38.842  1.00 46.93  ? 825  LEU A CD1 1 
ATOM   5852  C CD2 . LEU A 1 750 ? 5.127   8.776   40.149  1.00 50.59  ? 825  LEU A CD2 1 
ATOM   5853  N N   . LEU A 1 751 ? 7.088   10.996  35.579  1.00 78.91  ? 826  LEU A N   1 
ATOM   5854  C CA  . LEU A 1 751 ? 8.054   11.752  34.789  1.00 79.07  ? 826  LEU A CA  1 
ATOM   5855  C C   . LEU A 1 751 ? 7.642   13.215  34.659  1.00 80.29  ? 826  LEU A C   1 
ATOM   5856  O O   . LEU A 1 751 ? 8.501   14.105  34.647  1.00 81.44  ? 826  LEU A O   1 
ATOM   5857  C CB  . LEU A 1 751 ? 8.209   11.109  33.411  1.00 80.56  ? 826  LEU A CB  1 
ATOM   5858  C CG  . LEU A 1 751 ? 9.159   11.775  32.417  1.00 76.59  ? 826  LEU A CG  1 
ATOM   5859  C CD1 . LEU A 1 751 ? 10.569  11.812  32.976  1.00 82.09  ? 826  LEU A CD1 1 
ATOM   5860  C CD2 . LEU A 1 751 ? 9.124   11.035  31.091  1.00 88.93  ? 826  LEU A CD2 1 
ATOM   5861  N N   . SER A 1 752 ? 6.336   13.486  34.581  1.00 85.76  ? 827  SER A N   1 
ATOM   5862  C CA  . SER A 1 752 ? 5.862   14.864  34.517  1.00 88.18  ? 827  SER A CA  1 
ATOM   5863  C C   . SER A 1 752 ? 6.112   15.593  35.828  1.00 82.27  ? 827  SER A C   1 
ATOM   5864  O O   . SER A 1 752 ? 6.448   16.781  35.826  1.00 90.73  ? 827  SER A O   1 
ATOM   5865  C CB  . SER A 1 752 ? 4.374   14.893  34.169  1.00 79.64  ? 827  SER A CB  1 
ATOM   5866  O OG  . SER A 1 752 ? 4.093   14.074  33.048  1.00 105.67 ? 827  SER A OG  1 
ATOM   5867  N N   . PHE A 1 753 ? 5.939   14.903  36.958  1.00 75.13  ? 828  PHE A N   1 
ATOM   5868  C CA  . PHE A 1 753 ? 6.308   15.490  38.241  1.00 78.06  ? 828  PHE A CA  1 
ATOM   5869  C C   . PHE A 1 753 ? 7.787   15.840  38.269  1.00 80.47  ? 828  PHE A C   1 
ATOM   5870  O O   . PHE A 1 753 ? 8.170   16.916  38.742  1.00 80.65  ? 828  PHE A O   1 
ATOM   5871  C CB  . PHE A 1 753 ? 5.957   14.536  39.386  1.00 76.66  ? 828  PHE A CB  1 
ATOM   5872  C CG  . PHE A 1 753 ? 6.260   15.090  40.757  1.00 69.43  ? 828  PHE A CG  1 
ATOM   5873  C CD1 . PHE A 1 753 ? 7.546   15.053  41.277  1.00 80.57  ? 828  PHE A CD1 1 
ATOM   5874  C CD2 . PHE A 1 753 ? 5.257   15.663  41.519  1.00 77.51  ? 828  PHE A CD2 1 
ATOM   5875  C CE1 . PHE A 1 753 ? 7.822   15.570  42.530  1.00 83.97  ? 828  PHE A CE1 1 
ATOM   5876  C CE2 . PHE A 1 753 ? 5.527   16.180  42.775  1.00 89.17  ? 828  PHE A CE2 1 
ATOM   5877  C CZ  . PHE A 1 753 ? 6.812   16.133  43.280  1.00 84.13  ? 828  PHE A CZ  1 
ATOM   5878  N N   . ILE A 1 754 ? 8.636   14.937  37.774  1.00 79.68  ? 829  ILE A N   1 
ATOM   5879  C CA  . ILE A 1 754 ? 10.071  15.220  37.739  1.00 72.68  ? 829  ILE A CA  1 
ATOM   5880  C C   . ILE A 1 754 ? 10.352  16.444  36.873  1.00 78.91  ? 829  ILE A C   1 
ATOM   5881  O O   . ILE A 1 754 ? 11.126  17.331  37.251  1.00 74.98  ? 829  ILE A O   1 
ATOM   5882  C CB  . ILE A 1 754 ? 10.859  13.990  37.252  1.00 70.90  ? 829  ILE A CB  1 
ATOM   5883  C CG1 . ILE A 1 754 ? 10.757  12.862  38.275  1.00 70.97  ? 829  ILE A CG1 1 
ATOM   5884  C CG2 . ILE A 1 754 ? 12.315  14.354  37.011  1.00 82.17  ? 829  ILE A CG2 1 
ATOM   5885  C CD1 . ILE A 1 754 ? 11.239  13.256  39.653  1.00 73.47  ? 829  ILE A CD1 1 
ATOM   5886  N N   . LEU A 1 755 ? 9.712   16.517  35.703  1.00 77.70  ? 830  LEU A N   1 
ATOM   5887  C CA  . LEU A 1 755 ? 9.984   17.615  34.778  1.00 77.29  ? 830  LEU A CA  1 
ATOM   5888  C C   . LEU A 1 755 ? 9.484   18.949  35.321  1.00 78.75  ? 830  LEU A C   1 
ATOM   5889  O O   . LEU A 1 755 ? 10.136  19.983  35.133  1.00 79.15  ? 830  LEU A O   1 
ATOM   5890  C CB  . LEU A 1 755 ? 9.356   17.322  33.416  1.00 73.15  ? 830  LEU A CB  1 
ATOM   5891  C CG  . LEU A 1 755 ? 9.927   16.133  32.643  1.00 86.08  ? 830  LEU A CG  1 
ATOM   5892  C CD1 . LEU A 1 755 ? 9.051   15.802  31.447  1.00 85.94  ? 830  LEU A CD1 1 
ATOM   5893  C CD2 . LEU A 1 755 ? 11.350  16.430  32.198  1.00 97.89  ? 830  LEU A CD2 1 
ATOM   5894  N N   . ASP A 1 756 ? 8.330   18.948  35.994  1.00 83.34  ? 831  ASP A N   1 
ATOM   5895  C CA  . ASP A 1 756 ? 7.747   20.193  36.481  1.00 83.62  ? 831  ASP A CA  1 
ATOM   5896  C C   . ASP A 1 756 ? 8.421   20.675  37.760  1.00 80.42  ? 831  ASP A C   1 
ATOM   5897  O O   . ASP A 1 756 ? 8.608   21.882  37.945  1.00 80.13  ? 831  ASP A O   1 
ATOM   5898  C CB  . ASP A 1 756 ? 6.245   20.016  36.721  1.00 89.15  ? 831  ASP A CB  1 
ATOM   5899  C CG  . ASP A 1 756 ? 5.495   19.600  35.472  1.00 103.87 ? 831  ASP A CG  1 
ATOM   5900  O OD1 . ASP A 1 756 ? 6.089   19.654  34.375  1.00 110.51 ? 831  ASP A OD1 1 
ATOM   5901  O OD2 . ASP A 1 756 ? 4.313   19.213  35.592  1.00 92.25  ? 831  ASP A OD2 1 
ATOM   5902  N N   . HIS A 1 757 ? 8.792   19.753  38.649  1.00 81.39  ? 832  HIS A N   1 
ATOM   5903  C CA  . HIS A 1 757 ? 9.251   20.097  39.990  1.00 85.81  ? 832  HIS A CA  1 
ATOM   5904  C C   . HIS A 1 757 ? 10.766  20.041  40.140  1.00 91.12  ? 832  HIS A C   1 
ATOM   5905  O O   . HIS A 1 757 ? 11.376  21.010  40.600  1.00 92.69  ? 832  HIS A O   1 
ATOM   5906  C CB  . HIS A 1 757 ? 8.597   19.160  41.014  1.00 84.41  ? 832  HIS A CB  1 
ATOM   5907  C CG  . HIS A 1 757 ? 7.105   19.269  41.067  1.00 79.54  ? 832  HIS A CG  1 
ATOM   5908  N ND1 . HIS A 1 757 ? 6.436   19.805  42.147  1.00 97.72  ? 832  HIS A ND1 1 
ATOM   5909  C CD2 . HIS A 1 757 ? 6.152   18.905  40.177  1.00 89.76  ? 832  HIS A CD2 1 
ATOM   5910  C CE1 . HIS A 1 757 ? 5.136   19.773  41.917  1.00 100.21 ? 832  HIS A CE1 1 
ATOM   5911  N NE2 . HIS A 1 757 ? 4.937   19.231  40.728  1.00 99.30  ? 832  HIS A NE2 1 
ATOM   5912  N N   . VAL A 1 758 ? 11.383  18.916  39.774  1.00 86.07  ? 833  VAL A N   1 
ATOM   5913  C CA  . VAL A 1 758 ? 12.823  18.756  39.962  1.00 95.29  ? 833  VAL A CA  1 
ATOM   5914  C C   . VAL A 1 758 ? 13.587  19.734  39.079  1.00 88.04  ? 833  VAL A C   1 
ATOM   5915  O O   . VAL A 1 758 ? 14.381  20.549  39.565  1.00 88.19  ? 833  VAL A O   1 
ATOM   5916  C CB  . VAL A 1 758 ? 13.246  17.302  39.687  1.00 88.87  ? 833  VAL A CB  1 
ATOM   5917  C CG1 . VAL A 1 758 ? 14.762  17.198  39.565  1.00 85.71  ? 833  VAL A CG1 1 
ATOM   5918  C CG2 . VAL A 1 758 ? 12.727  16.381  40.785  1.00 80.29  ? 833  VAL A CG2 1 
ATOM   5919  N N   . PHE A 1 759 ? 13.364  19.664  37.771  1.00 81.76  ? 834  PHE A N   1 
ATOM   5920  C CA  . PHE A 1 759 ? 14.020  20.570  36.837  1.00 91.71  ? 834  PHE A CA  1 
ATOM   5921  C C   . PHE A 1 759 ? 13.223  21.866  36.750  1.00 98.15  ? 834  PHE A C   1 
ATOM   5922  O O   . PHE A 1 759 ? 12.062  21.862  36.328  1.00 105.44 ? 834  PHE A O   1 
ATOM   5923  C CB  . PHE A 1 759 ? 14.155  19.916  35.465  1.00 84.93  ? 834  PHE A CB  1 
ATOM   5924  C CG  . PHE A 1 759 ? 14.881  18.601  35.494  1.00 90.59  ? 834  PHE A CG  1 
ATOM   5925  C CD1 . PHE A 1 759 ? 16.155  18.508  36.031  1.00 94.38  ? 834  PHE A CD1 1 
ATOM   5926  C CD2 . PHE A 1 759 ? 14.284  17.455  34.997  1.00 96.68  ? 834  PHE A CD2 1 
ATOM   5927  C CE1 . PHE A 1 759 ? 16.822  17.297  36.064  1.00 89.86  ? 834  PHE A CE1 1 
ATOM   5928  C CE2 . PHE A 1 759 ? 14.946  16.242  35.028  1.00 100.59 ? 834  PHE A CE2 1 
ATOM   5929  C CZ  . PHE A 1 759 ? 16.216  16.162  35.562  1.00 91.15  ? 834  PHE A CZ  1 
ATOM   5930  N N   . ILE A 1 760 ? 13.846  22.972  37.152  1.00 100.97 ? 835  ILE A N   1 
ATOM   5931  C CA  . ILE A 1 760 ? 13.206  24.279  37.219  1.00 95.97  ? 835  ILE A CA  1 
ATOM   5932  C C   . ILE A 1 760 ? 14.152  25.342  36.665  1.00 122.53 ? 835  ILE A C   1 
ATOM   5933  O O   . ILE A 1 760 ? 15.266  25.048  36.223  1.00 131.14 ? 835  ILE A O   1 
ATOM   5934  C CB  . ILE A 1 760 ? 12.725  24.618  38.654  1.00 86.52  ? 835  ILE A CB  1 
ATOM   5935  C CG1 . ILE A 1 760 ? 13.800  24.392  39.742  1.00 97.43  ? 835  ILE A CG1 1 
ATOM   5936  C CG2 . ILE A 1 760 ? 11.464  23.834  38.988  1.00 89.68  ? 835  ILE A CG2 1 
ATOM   5937  C CD1 . ILE A 1 760 ? 15.130  25.115  39.617  1.00 122.45 ? 835  ILE A CD1 1 
ATOM   5938  N N   . GLU A 1 761 ? 13.691  26.591  36.687  1.00 116.85 ? 836  GLU A N   1 
ATOM   5939  C CA  . GLU A 1 761 ? 14.494  27.700  36.193  1.00 129.55 ? 836  GLU A CA  1 
ATOM   5940  C C   . GLU A 1 761 ? 15.692  27.929  37.106  1.00 139.64 ? 836  GLU A C   1 
ATOM   5941  O O   . GLU A 1 761 ? 15.543  28.057  38.326  1.00 145.85 ? 836  GLU A O   1 
ATOM   5942  C CB  . GLU A 1 761 ? 13.640  28.967  36.097  1.00 140.69 ? 836  GLU A CB  1 
ATOM   5943  C CG  . GLU A 1 761 ? 14.418  30.251  35.818  1.00 161.39 ? 836  GLU A CG  1 
ATOM   5944  C CD  . GLU A 1 761 ? 14.848  30.969  37.087  1.00 168.61 ? 836  GLU A CD  1 
ATOM   5945  O OE1 . GLU A 1 761 ? 14.328  30.629  38.171  1.00 179.11 ? 836  GLU A OE1 1 
ATOM   5946  O OE2 . GLU A 1 761 ? 15.705  31.874  36.999  1.00 158.94 ? 836  GLU A OE2 1 
ATOM   5947  N N   . GLN A 1 762 ? 16.883  27.981  36.513  1.00 139.20 ? 837  GLN A N   1 
ATOM   5948  C CA  . GLN A 1 762 ? 18.108  28.197  37.273  1.00 143.40 ? 837  GLN A CA  1 
ATOM   5949  C C   . GLN A 1 762 ? 18.296  29.689  37.522  1.00 147.55 ? 837  GLN A C   1 
ATOM   5950  O O   . GLN A 1 762 ? 18.388  30.477  36.574  1.00 145.03 ? 837  GLN A O   1 
ATOM   5951  C CB  . GLN A 1 762 ? 19.317  27.614  36.541  1.00 135.74 ? 837  GLN A CB  1 
ATOM   5952  C CG  . GLN A 1 762 ? 19.131  26.194  36.012  1.00 122.84 ? 837  GLN A CG  1 
ATOM   5953  C CD  . GLN A 1 762 ? 18.452  26.149  34.654  1.00 133.95 ? 837  GLN A CD  1 
ATOM   5954  O OE1 . GLN A 1 762 ? 19.033  26.543  33.644  1.00 131.15 ? 837  GLN A OE1 1 
ATOM   5955  N NE2 . GLN A 1 762 ? 17.216  25.661  34.626  1.00 135.39 ? 837  GLN A NE2 1 
ATOM   5956  N N   . ASP A 1 763 ? 18.353  30.070  38.794  1.00 147.44 ? 838  ASP A N   1 
ATOM   5957  C CA  . ASP A 1 763 ? 18.501  31.469  39.179  1.00 142.78 ? 838  ASP A CA  1 
ATOM   5958  C C   . ASP A 1 763 ? 19.927  31.774  39.629  1.00 138.52 ? 838  ASP A C   1 
ATOM   5959  O O   . ASP A 1 763 ? 20.772  32.166  38.824  1.00 140.04 ? 838  ASP A O   1 
ATOM   5960  C CB  . ASP A 1 763 ? 17.509  31.818  40.291  1.00 134.43 ? 838  ASP A CB  1 
ATOM   5961  C CG  . ASP A 1 763 ? 17.419  30.736  41.353  1.00 138.66 ? 838  ASP A CG  1 
ATOM   5962  O OD1 . ASP A 1 763 ? 16.427  30.728  42.112  1.00 140.92 ? 838  ASP A OD1 1 
ATOM   5963  O OD2 . ASP A 1 763 ? 18.338  29.895  41.429  1.00 135.55 ? 838  ASP A OD2 1 
ATOM   5964  N N   . ASP A 1 775 ? 16.840  32.428  52.878  1.00 136.55 ? 850  ASP A N   1 
ATOM   5965  C CA  . ASP A 1 775 ? 17.678  32.903  51.782  1.00 131.33 ? 850  ASP A CA  1 
ATOM   5966  C C   . ASP A 1 775 ? 18.450  31.761  51.118  1.00 141.45 ? 850  ASP A C   1 
ATOM   5967  O O   . ASP A 1 775 ? 17.847  30.825  50.593  1.00 138.31 ? 850  ASP A O   1 
ATOM   5968  C CB  . ASP A 1 775 ? 18.638  33.981  52.285  1.00 135.59 ? 850  ASP A CB  1 
ATOM   5969  C CG  . ASP A 1 775 ? 19.227  33.649  53.639  1.00 141.66 ? 850  ASP A CG  1 
ATOM   5970  O OD1 . ASP A 1 775 ? 19.085  32.487  54.076  1.00 151.29 ? 850  ASP A OD1 1 
ATOM   5971  O OD2 . ASP A 1 775 ? 19.827  34.546  54.266  1.00 122.01 ? 850  ASP A OD2 1 
ATOM   5972  N N   . GLU A 1 776 ? 19.784  31.844  51.137  1.00 144.38 ? 851  GLU A N   1 
ATOM   5973  C CA  . GLU A 1 776 ? 20.598  30.825  50.478  1.00 141.22 ? 851  GLU A CA  1 
ATOM   5974  C C   . GLU A 1 776 ? 20.399  29.456  51.124  1.00 141.59 ? 851  GLU A C   1 
ATOM   5975  O O   . GLU A 1 776 ? 20.347  28.433  50.429  1.00 141.87 ? 851  GLU A O   1 
ATOM   5976  C CB  . GLU A 1 776 ? 22.072  31.238  50.505  1.00 151.70 ? 851  GLU A CB  1 
ATOM   5977  C CG  . GLU A 1 776 ? 22.977  30.471  49.545  1.00 167.17 ? 851  GLU A CG  1 
ATOM   5978  C CD  . GLU A 1 776 ? 23.632  29.269  50.198  1.00 178.40 ? 851  GLU A CD  1 
ATOM   5979  O OE1 . GLU A 1 776 ? 23.481  29.107  51.426  1.00 210.76 ? 851  GLU A OE1 1 
ATOM   5980  O OE2 . GLU A 1 776 ? 24.307  28.494  49.486  1.00 166.35 ? 851  GLU A OE2 1 
ATOM   5981  N N   . ALA A 1 777 ? 20.263  29.421  52.453  1.00 145.42 ? 852  ALA A N   1 
ATOM   5982  C CA  . ALA A 1 777 ? 20.040  28.153  53.143  1.00 140.22 ? 852  ALA A CA  1 
ATOM   5983  C C   . ALA A 1 777 ? 18.693  27.547  52.766  1.00 146.58 ? 852  ALA A C   1 
ATOM   5984  O O   . ALA A 1 777 ? 18.566  26.322  52.637  1.00 167.58 ? 852  ALA A O   1 
ATOM   5985  C CB  . ALA A 1 777 ? 20.133  28.358  54.655  1.00 134.46 ? 852  ALA A CB  1 
ATOM   5986  N N   . SER A 1 778 ? 17.672  28.389  52.586  1.00 142.31 ? 853  SER A N   1 
ATOM   5987  C CA  . SER A 1 778 ? 16.378  27.886  52.139  1.00 139.53 ? 853  SER A CA  1 
ATOM   5988  C C   . SER A 1 778 ? 16.474  27.307  50.733  1.00 137.97 ? 853  SER A C   1 
ATOM   5989  O O   . SER A 1 778 ? 15.842  26.286  50.425  1.00 128.28 ? 853  SER A O   1 
ATOM   5990  C CB  . SER A 1 778 ? 15.335  29.002  52.198  1.00 137.54 ? 853  SER A CB  1 
ATOM   5991  O OG  . SER A 1 778 ? 15.422  29.842  51.061  1.00 147.87 ? 853  SER A OG  1 
ATOM   5992  N N   . LYS A 1 779 ? 17.266  27.943  49.865  1.00 135.43 ? 854  LYS A N   1 
ATOM   5993  C CA  . LYS A 1 779 ? 17.515  27.380  48.543  1.00 128.55 ? 854  LYS A CA  1 
ATOM   5994  C C   . LYS A 1 779 ? 18.204  26.025  48.647  1.00 125.83 ? 854  LYS A C   1 
ATOM   5995  O O   . LYS A 1 779 ? 17.895  25.105  47.881  1.00 126.95 ? 854  LYS A O   1 
ATOM   5996  C CB  . LYS A 1 779 ? 18.355  28.344  47.704  1.00 119.78 ? 854  LYS A CB  1 
ATOM   5997  C CG  . LYS A 1 779 ? 17.702  29.690  47.439  1.00 133.67 ? 854  LYS A CG  1 
ATOM   5998  C CD  . LYS A 1 779 ? 18.753  30.767  47.223  1.00 133.96 ? 854  LYS A CD  1 
ATOM   5999  C CE  . LYS A 1 779 ? 18.772  31.246  45.779  1.00 116.66 ? 854  LYS A CE  1 
ATOM   6000  N NZ  . LYS A 1 779 ? 19.246  30.188  44.845  1.00 109.66 ? 854  LYS A NZ  1 
ATOM   6001  N N   . ILE A 1 780 ? 19.137  25.883  49.594  1.00 127.53 ? 855  ILE A N   1 
ATOM   6002  C CA  . ILE A 1 780 ? 19.817  24.600  49.784  1.00 121.53 ? 855  ILE A CA  1 
ATOM   6003  C C   . ILE A 1 780 ? 18.823  23.527  50.221  1.00 112.30 ? 855  ILE A C   1 
ATOM   6004  O O   . ILE A 1 780 ? 18.861  22.385  49.741  1.00 117.32 ? 855  ILE A O   1 
ATOM   6005  C CB  . ILE A 1 780 ? 20.969  24.753  50.795  1.00 112.79 ? 855  ILE A CB  1 
ATOM   6006  C CG1 . ILE A 1 780 ? 22.016  25.743  50.275  1.00 121.99 ? 855  ILE A CG1 1 
ATOM   6007  C CG2 . ILE A 1 780 ? 21.606  23.407  51.091  1.00 106.41 ? 855  ILE A CG2 1 
ATOM   6008  C CD1 . ILE A 1 780 ? 22.401  25.533  48.826  1.00 123.72 ? 855  ILE A CD1 1 
ATOM   6009  N N   . GLU A 1 781 ? 17.920  23.879  51.137  1.00 111.02 ? 856  GLU A N   1 
ATOM   6010  C CA  . GLU A 1 781 ? 16.909  22.927  51.593  1.00 113.24 ? 856  GLU A CA  1 
ATOM   6011  C C   . GLU A 1 781 ? 15.999  22.499  50.444  1.00 113.46 ? 856  GLU A C   1 
ATOM   6012  O O   . GLU A 1 781 ? 15.699  21.306  50.273  1.00 115.08 ? 856  GLU A O   1 
ATOM   6013  C CB  . GLU A 1 781 ? 16.098  23.543  52.734  1.00 119.13 ? 856  GLU A CB  1 
ATOM   6014  C CG  . GLU A 1 781 ? 16.917  23.869  53.979  1.00 132.63 ? 856  GLU A CG  1 
ATOM   6015  C CD  . GLU A 1 781 ? 16.485  25.159  54.652  1.00 158.70 ? 856  GLU A CD  1 
ATOM   6016  O OE1 . GLU A 1 781 ? 15.306  25.542  54.507  1.00 143.19 ? 856  GLU A OE1 1 
ATOM   6017  O OE2 . GLU A 1 781 ? 17.325  25.787  55.333  1.00 167.68 ? 856  GLU A OE2 1 
ATOM   6018  N N   . ALA A 1 782 ? 15.549  23.468  49.641  1.00 108.62 ? 857  ALA A N   1 
ATOM   6019  C CA  . ALA A 1 782 ? 14.710  23.150  48.489  1.00 111.59 ? 857  ALA A CA  1 
ATOM   6020  C C   . ALA A 1 782 ? 15.445  22.250  47.500  1.00 107.14 ? 857  ALA A C   1 
ATOM   6021  O O   . ALA A 1 782 ? 14.859  21.309  46.946  1.00 100.33 ? 857  ALA A O   1 
ATOM   6022  C CB  . ALA A 1 782 ? 14.251  24.438  47.805  1.00 101.39 ? 857  ALA A CB  1 
ATOM   6023  N N   . LEU A 1 783 ? 16.731  22.528  47.266  1.00 108.49 ? 858  LEU A N   1 
ATOM   6024  C CA  . LEU A 1 783 ? 17.518  21.696  46.362  1.00 95.53  ? 858  LEU A CA  1 
ATOM   6025  C C   . LEU A 1 783 ? 17.637  20.272  46.886  1.00 102.76 ? 858  LEU A C   1 
ATOM   6026  O O   . LEU A 1 783 ? 17.597  19.315  46.109  1.00 111.13 ? 858  LEU A O   1 
ATOM   6027  C CB  . LEU A 1 783 ? 18.905  22.306  46.152  1.00 88.00  ? 858  LEU A CB  1 
ATOM   6028  C CG  . LEU A 1 783 ? 19.912  21.411  45.421  1.00 96.23  ? 858  LEU A CG  1 
ATOM   6029  C CD1 . LEU A 1 783 ? 19.412  21.059  44.026  1.00 94.96  ? 858  LEU A CD1 1 
ATOM   6030  C CD2 . LEU A 1 783 ? 21.282  22.066  45.355  1.00 106.46 ? 858  LEU A CD2 1 
ATOM   6031  N N   . HIS A 1 784 ? 17.787  20.110  48.202  1.00 99.42  ? 859  HIS A N   1 
ATOM   6032  C CA  . HIS A 1 784 ? 17.871  18.761  48.758  1.00 94.75  ? 859  HIS A CA  1 
ATOM   6033  C C   . HIS A 1 784 ? 16.556  18.007  48.577  1.00 89.24  ? 859  HIS A C   1 
ATOM   6034  O O   . HIS A 1 784 ? 16.553  16.814  48.233  1.00 86.35  ? 859  HIS A O   1 
ATOM   6035  C CB  . HIS A 1 784 ? 18.265  18.822  50.232  1.00 94.56  ? 859  HIS A CB  1 
ATOM   6036  C CG  . HIS A 1 784 ? 19.734  19.010  50.456  1.00 99.05  ? 859  HIS A CG  1 
ATOM   6037  N ND1 . HIS A 1 784 ? 20.251  20.099  51.123  1.00 100.39 ? 859  HIS A ND1 1 
ATOM   6038  C CD2 . HIS A 1 784 ? 20.795  18.247  50.103  1.00 85.16  ? 859  HIS A CD2 1 
ATOM   6039  C CE1 . HIS A 1 784 ? 21.567  19.999  51.173  1.00 97.55  ? 859  HIS A CE1 1 
ATOM   6040  N NE2 . HIS A 1 784 ? 21.923  18.884  50.560  1.00 90.36  ? 859  HIS A NE2 1 
ATOM   6041  N N   . LYS A 1 785 ? 15.427  18.688  48.796  1.00 94.31  ? 860  LYS A N   1 
ATOM   6042  C CA  . LYS A 1 785 ? 14.137  18.035  48.566  1.00 104.17 ? 860  LYS A CA  1 
ATOM   6043  C C   . LYS A 1 785 ? 13.982  17.627  47.099  1.00 96.96  ? 860  LYS A C   1 
ATOM   6044  O O   . LYS A 1 785 ? 13.540  16.506  46.792  1.00 92.25  ? 860  LYS A O   1 
ATOM   6045  C CB  . LYS A 1 785 ? 12.994  18.949  49.028  1.00 95.48  ? 860  LYS A CB  1 
ATOM   6046  C CG  . LYS A 1 785 ? 12.212  19.655  47.926  1.00 106.66 ? 860  LYS A CG  1 
ATOM   6047  C CD  . LYS A 1 785 ? 10.995  20.388  48.466  1.00 119.13 ? 860  LYS A CD  1 
ATOM   6048  C CE  . LYS A 1 785 ? 10.363  21.258  47.391  1.00 117.53 ? 860  LYS A CE  1 
ATOM   6049  N NZ  . LYS A 1 785 ? 9.372   22.212  47.953  1.00 116.39 ? 860  LYS A NZ  1 
ATOM   6050  N N   . ARG A 1 786 ? 14.384  18.509  46.176  1.00 87.78  ? 861  ARG A N   1 
ATOM   6051  C CA  . ARG A 1 786 ? 14.286  18.186  44.755  1.00 79.73  ? 861  ARG A CA  1 
ATOM   6052  C C   . ARG A 1 786 ? 15.205  17.026  44.390  1.00 81.04  ? 861  ARG A C   1 
ATOM   6053  O O   . ARG A 1 786 ? 14.852  16.180  43.556  1.00 83.47  ? 861  ARG A O   1 
ATOM   6054  C CB  . ARG A 1 786 ? 14.607  19.421  43.910  1.00 74.53  ? 861  ARG A CB  1 
ATOM   6055  C CG  . ARG A 1 786 ? 13.378  20.214  43.484  1.00 78.82  ? 861  ARG A CG  1 
ATOM   6056  C CD  . ARG A 1 786 ? 13.579  21.724  43.575  1.00 85.08  ? 861  ARG A CD  1 
ATOM   6057  N NE  . ARG A 1 786 ? 14.802  22.167  42.916  1.00 91.75  ? 861  ARG A NE  1 
ATOM   6058  C CZ  . ARG A 1 786 ? 15.674  23.015  43.445  1.00 92.51  ? 861  ARG A CZ  1 
ATOM   6059  N NH1 . ARG A 1 786 ? 15.466  23.570  44.628  1.00 88.55  ? 861  ARG A NH1 1 
ATOM   6060  N NH2 . ARG A 1 786 ? 16.777  23.319  42.767  1.00 87.62  ? 861  ARG A NH2 1 
ATOM   6061  N N   . ARG A 1 787 ? 16.387  16.969  45.009  1.00 71.37  ? 862  ARG A N   1 
ATOM   6062  C CA  . ARG A 1 787 ? 17.317  15.880  44.738  1.00 81.79  ? 862  ARG A CA  1 
ATOM   6063  C C   . ARG A 1 787 ? 16.747  14.551  45.207  1.00 72.86  ? 862  ARG A C   1 
ATOM   6064  O O   . ARG A 1 787 ? 16.898  13.531  44.528  1.00 66.59  ? 862  ARG A O   1 
ATOM   6065  C CB  . ARG A 1 787 ? 18.664  16.157  45.409  1.00 85.15  ? 862  ARG A CB  1 
ATOM   6066  C CG  . ARG A 1 787 ? 19.500  17.207  44.691  1.00 80.94  ? 862  ARG A CG  1 
ATOM   6067  C CD  . ARG A 1 787 ? 20.859  17.410  45.344  1.00 78.04  ? 862  ARG A CD  1 
ATOM   6068  N NE  . ARG A 1 787 ? 21.791  16.331  45.044  1.00 68.90  ? 862  ARG A NE  1 
ATOM   6069  C CZ  . ARG A 1 787 ? 22.170  15.403  45.913  1.00 92.54  ? 862  ARG A CZ  1 
ATOM   6070  N NH1 . ARG A 1 787 ? 21.717  15.392  47.157  1.00 102.24 ? 862  ARG A NH1 1 
ATOM   6071  N NH2 . ARG A 1 787 ? 23.033  14.467  45.527  1.00 89.84  ? 862  ARG A NH2 1 
ATOM   6072  N N   . ASN A 1 788 ? 16.077  14.543  46.362  1.00 72.85  ? 863  ASN A N   1 
ATOM   6073  C CA  . ASN A 1 788 ? 15.470  13.300  46.831  1.00 64.33  ? 863  ASN A CA  1 
ATOM   6074  C C   . ASN A 1 788 ? 14.344  12.853  45.903  1.00 74.19  ? 863  ASN A C   1 
ATOM   6075  O O   . ASN A 1 788 ? 14.199  11.654  45.626  1.00 63.12  ? 863  ASN A O   1 
ATOM   6076  C CB  . ASN A 1 788 ? 14.965  13.463  48.264  1.00 62.28  ? 863  ASN A CB  1 
ATOM   6077  C CG  . ASN A 1 788 ? 14.318  12.199  48.802  1.00 75.80  ? 863  ASN A CG  1 
ATOM   6078  O OD1 . ASN A 1 788 ? 13.194  12.226  49.304  1.00 80.36  ? 863  ASN A OD1 1 
ATOM   6079  N ND2 . ASN A 1 788 ? 15.027  11.080  48.695  1.00 74.63  ? 863  ASN A ND2 1 
ATOM   6080  N N   . LEU A 1 789 ? 13.546  13.802  45.400  1.00 75.33  ? 864  LEU A N   1 
ATOM   6081  C CA  . LEU A 1 789 ? 12.492  13.453  44.444  1.00 67.53  ? 864  LEU A CA  1 
ATOM   6082  C C   . LEU A 1 789 ? 13.077  12.824  43.178  1.00 76.69  ? 864  LEU A C   1 
ATOM   6083  O O   . LEU A 1 789 ? 12.649  11.739  42.731  1.00 70.19  ? 864  LEU A O   1 
ATOM   6084  C CB  . LEU A 1 789 ? 11.689  14.705  44.090  1.00 70.00  ? 864  LEU A CB  1 
ATOM   6085  C CG  . LEU A 1 789 ? 10.930  15.409  45.215  1.00 67.24  ? 864  LEU A CG  1 
ATOM   6086  C CD1 . LEU A 1 789 ? 10.393  16.745  44.729  1.00 78.57  ? 864  LEU A CD1 1 
ATOM   6087  C CD2 . LEU A 1 789 ? 9.803   14.539  45.740  1.00 75.33  ? 864  LEU A CD2 1 
ATOM   6088  N N   . LEU A 1 790 ? 14.049  13.518  42.574  1.00 75.71  ? 865  LEU A N   1 
ATOM   6089  C CA  . LEU A 1 790 ? 14.715  12.998  41.386  1.00 77.62  ? 865  LEU A CA  1 
ATOM   6090  C C   . LEU A 1 790 ? 15.321  11.628  41.649  1.00 70.86  ? 865  LEU A C   1 
ATOM   6091  O O   . LEU A 1 790 ? 15.261  10.742  40.792  1.00 70.53  ? 865  LEU A O   1 
ATOM   6092  C CB  . LEU A 1 790 ? 15.800  13.967  40.923  1.00 70.11  ? 865  LEU A CB  1 
ATOM   6093  C CG  . LEU A 1 790 ? 16.563  13.482  39.689  1.00 68.28  ? 865  LEU A CG  1 
ATOM   6094  C CD1 . LEU A 1 790 ? 15.693  13.552  38.440  1.00 77.43  ? 865  LEU A CD1 1 
ATOM   6095  C CD2 . LEU A 1 790 ? 17.847  14.250  39.505  1.00 67.94  ? 865  LEU A CD2 1 
ATOM   6096  N N   . ALA A 1 791 ? 15.915  11.438  42.831  1.00 65.46  ? 866  ALA A N   1 
ATOM   6097  C CA  . ALA A 1 791 ? 16.518  10.154  43.162  1.00 66.29  ? 866  ALA A CA  1 
ATOM   6098  C C   . ALA A 1 791 ? 15.471  9.060   43.280  1.00 70.19  ? 866  ALA A C   1 
ATOM   6099  O O   . ALA A 1 791 ? 15.749  7.908   42.945  1.00 67.54  ? 866  ALA A O   1 
ATOM   6100  C CB  . ALA A 1 791 ? 17.321  10.267  44.458  1.00 70.17  ? 866  ALA A CB  1 
ATOM   6101  N N   . ALA A 1 792 ? 14.268  9.393   43.750  1.00 69.39  ? 867  ALA A N   1 
ATOM   6102  C CA  . ALA A 1 792 ? 13.194  8.403   43.760  1.00 70.95  ? 867  ALA A CA  1 
ATOM   6103  C C   . ALA A 1 792 ? 12.876  7.929   42.345  1.00 71.25  ? 867  ALA A C   1 
ATOM   6104  O O   . ALA A 1 792 ? 12.881  6.717   42.056  1.00 72.71  ? 867  ALA A O   1 
ATOM   6105  C CB  . ALA A 1 792 ? 11.949  8.982   44.432  1.00 63.48  ? 867  ALA A CB  1 
ATOM   6106  N N   . PHE A 1 793 ? 12.609  8.875   41.439  1.00 75.63  ? 868  PHE A N   1 
ATOM   6107  C CA  . PHE A 1 793 ? 12.282  8.441   40.077  1.00 75.22  ? 868  PHE A CA  1 
ATOM   6108  C C   . PHE A 1 793 ? 13.463  7.735   39.411  1.00 74.10  ? 868  PHE A C   1 
ATOM   6109  O O   . PHE A 1 793 ? 13.273  6.774   38.650  1.00 72.70  ? 868  PHE A O   1 
ATOM   6110  C CB  . PHE A 1 793 ? 11.809  9.612   39.218  1.00 72.43  ? 868  PHE A CB  1 
ATOM   6111  C CG  . PHE A 1 793 ? 11.250  9.190   37.883  1.00 84.24  ? 868  PHE A CG  1 
ATOM   6112  C CD1 . PHE A 1 793 ? 10.194  8.292   37.817  1.00 83.97  ? 868  PHE A CD1 1 
ATOM   6113  C CD2 . PHE A 1 793 ? 11.780  9.679   36.700  1.00 82.94  ? 868  PHE A CD2 1 
ATOM   6114  C CE1 . PHE A 1 793 ? 9.679   7.890   36.597  1.00 90.38  ? 868  PHE A CE1 1 
ATOM   6115  C CE2 . PHE A 1 793 ? 11.268  9.283   35.473  1.00 76.24  ? 868  PHE A CE2 1 
ATOM   6116  C CZ  . PHE A 1 793 ? 10.216  8.387   35.423  1.00 88.18  ? 868  PHE A CZ  1 
ATOM   6117  N N   . CYS A 1 794 ? 14.688  8.166   39.713  1.00 71.92  ? 869  CYS A N   1 
ATOM   6118  C CA  . CYS A 1 794 ? 15.867  7.534   39.135  1.00 53.34  ? 869  CYS A CA  1 
ATOM   6119  C C   . CYS A 1 794 ? 16.082  6.134   39.689  1.00 64.90  ? 869  CYS A C   1 
ATOM   6120  O O   . CYS A 1 794 ? 16.588  5.262   38.977  1.00 70.54  ? 869  CYS A O   1 
ATOM   6121  C CB  . CYS A 1 794 ? 17.101  8.399   39.389  1.00 60.36  ? 869  CYS A CB  1 
ATOM   6122  S SG  . CYS A 1 794 ? 17.228  9.845   38.309  1.00 66.13  ? 869  CYS A SG  1 
ATOM   6123  N N   . LYS A 1 795 ? 15.726  5.907   40.956  1.00 68.41  ? 870  LYS A N   1 
ATOM   6124  C CA  . LYS A 1 795 ? 15.717  4.552   41.493  1.00 66.24  ? 870  LYS A CA  1 
ATOM   6125  C C   . LYS A 1 795 ? 14.745  3.683   40.717  1.00 66.16  ? 870  LYS A C   1 
ATOM   6126  O O   . LYS A 1 795 ? 15.045  2.525   40.404  1.00 66.68  ? 870  LYS A O   1 
ATOM   6127  C CB  . LYS A 1 795 ? 15.337  4.564   42.976  1.00 53.28  ? 870  LYS A CB  1 
ATOM   6128  C CG  . LYS A 1 795 ? 16.465  4.886   43.939  1.00 57.92  ? 870  LYS A CG  1 
ATOM   6129  C CD  . LYS A 1 795 ? 15.959  4.870   45.378  1.00 58.25  ? 870  LYS A CD  1 
ATOM   6130  C CE  . LYS A 1 795 ? 15.054  6.057   45.665  1.00 63.53  ? 870  LYS A CE  1 
ATOM   6131  N NZ  . LYS A 1 795 ? 15.726  7.117   46.467  1.00 55.28  ? 870  LYS A NZ  1 
ATOM   6132  N N   . LEU A 1 796 ? 13.565  4.226   40.406  1.00 74.06  ? 871  LEU A N   1 
ATOM   6133  C CA  . LEU A 1 796 ? 12.648  3.486   39.542  1.00 72.62  ? 871  LEU A CA  1 
ATOM   6134  C C   . LEU A 1 796 ? 13.302  3.140   38.208  1.00 77.38  ? 871  LEU A C   1 
ATOM   6135  O O   . LEU A 1 796 ? 13.155  2.018   37.709  1.00 82.09  ? 871  LEU A O   1 
ATOM   6136  C CB  . LEU A 1 796 ? 11.358  4.272   39.316  1.00 68.80  ? 871  LEU A CB  1 
ATOM   6137  C CG  . LEU A 1 796 ? 10.575  4.654   40.568  1.00 79.29  ? 871  LEU A CG  1 
ATOM   6138  C CD1 . LEU A 1 796 ? 9.332   5.431   40.179  1.00 74.13  ? 871  LEU A CD1 1 
ATOM   6139  C CD2 . LEU A 1 796 ? 10.211  3.409   41.364  1.00 70.93  ? 871  LEU A CD2 1 
ATOM   6140  N N   . ILE A 1 797 ? 14.036  4.089   37.621  1.00 73.37  ? 872  ILE A N   1 
ATOM   6141  C CA  . ILE A 1 797 ? 14.666  3.838   36.321  1.00 65.87  ? 872  ILE A CA  1 
ATOM   6142  C C   . ILE A 1 797 ? 15.724  2.742   36.427  1.00 74.95  ? 872  ILE A C   1 
ATOM   6143  O O   . ILE A 1 797 ? 15.712  1.769   35.664  1.00 80.64  ? 872  ILE A O   1 
ATOM   6144  C CB  . ILE A 1 797 ? 15.262  5.132   35.738  1.00 58.56  ? 872  ILE A CB  1 
ATOM   6145  C CG1 . ILE A 1 797 ? 14.205  6.234   35.668  1.00 70.34  ? 872  ILE A CG1 1 
ATOM   6146  C CG2 . ILE A 1 797 ? 15.874  4.868   34.371  1.00 52.99  ? 872  ILE A CG2 1 
ATOM   6147  C CD1 . ILE A 1 797 ? 14.762  7.577   35.252  1.00 68.25  ? 872  ILE A CD1 1 
ATOM   6148  N N   . VAL A 1 798 ? 16.661  2.888   37.368  1.00 75.23  ? 873  VAL A N   1 
ATOM   6149  C CA  . VAL A 1 798 ? 17.822  2.003   37.418  1.00 74.73  ? 873  VAL A CA  1 
ATOM   6150  C C   . VAL A 1 798 ? 17.456  0.588   37.839  1.00 76.78  ? 873  VAL A C   1 
ATOM   6151  O O   . VAL A 1 798 ? 18.194  -0.355  37.533  1.00 84.23  ? 873  VAL A O   1 
ATOM   6152  C CB  . VAL A 1 798 ? 18.899  2.571   38.363  1.00 68.95  ? 873  VAL A CB  1 
ATOM   6153  C CG1 . VAL A 1 798 ? 19.352  3.939   37.886  1.00 68.50  ? 873  VAL A CG1 1 
ATOM   6154  C CG2 . VAL A 1 798 ? 18.378  2.640   39.789  1.00 64.53  ? 873  VAL A CG2 1 
ATOM   6155  N N   . TYR A 1 799 ? 16.340  0.411   38.544  1.00 76.28  ? 874  TYR A N   1 
ATOM   6156  C CA  . TYR A 1 799 ? 15.886  -0.908  38.957  1.00 80.15  ? 874  TYR A CA  1 
ATOM   6157  C C   . TYR A 1 799 ? 14.790  -1.442  38.044  1.00 83.74  ? 874  TYR A C   1 
ATOM   6158  O O   . TYR A 1 799 ? 14.049  -2.352  38.435  1.00 97.73  ? 874  TYR A O   1 
ATOM   6159  C CB  . TYR A 1 799 ? 15.421  -0.870  40.413  1.00 80.42  ? 874  TYR A CB  1 
ATOM   6160  C CG  . TYR A 1 799 ? 16.558  -0.605  41.374  1.00 88.55  ? 874  TYR A CG  1 
ATOM   6161  C CD1 . TYR A 1 799 ? 17.568  -1.539  41.557  1.00 95.76  ? 874  TYR A CD1 1 
ATOM   6162  C CD2 . TYR A 1 799 ? 16.632  0.586   42.084  1.00 87.87  ? 874  TYR A CD2 1 
ATOM   6163  C CE1 . TYR A 1 799 ? 18.615  -1.298  42.424  1.00 99.01  ? 874  TYR A CE1 1 
ATOM   6164  C CE2 . TYR A 1 799 ? 17.675  0.837   42.952  1.00 97.35  ? 874  TYR A CE2 1 
ATOM   6165  C CZ  . TYR A 1 799 ? 18.663  -0.110  43.120  1.00 103.27 ? 874  TYR A CZ  1 
ATOM   6166  O OH  . TYR A 1 799 ? 19.704  0.132   43.986  1.00 97.98  ? 874  TYR A OH  1 
ATOM   6167  N N   . THR A 1 800 ? 14.678  -0.882  36.837  1.00 88.25  ? 875  THR A N   1 
ATOM   6168  C CA  . THR A 1 800 ? 13.769  -1.327  35.780  1.00 97.46  ? 875  THR A CA  1 
ATOM   6169  C C   . THR A 1 800 ? 12.303  -1.292  36.201  1.00 92.64  ? 875  THR A C   1 
ATOM   6170  O O   . THR A 1 800 ? 11.467  -1.967  35.593  1.00 78.25  ? 875  THR A O   1 
ATOM   6171  C CB  . THR A 1 800 ? 14.140  -2.728  35.273  1.00 93.95  ? 875  THR A CB  1 
ATOM   6172  O OG1 . THR A 1 800 ? 13.793  -3.711  36.256  1.00 91.40  ? 875  THR A OG1 1 
ATOM   6173  C CG2 . THR A 1 800 ? 15.634  -2.809  34.978  1.00 86.98  ? 875  THR A CG2 1 
ATOM   6174  N N   . VAL A 1 801 ? 11.966  -0.506  37.226  1.00 93.07  ? 876  VAL A N   1 
ATOM   6175  C CA  . VAL A 1 801 ? 10.564  -0.362  37.608  1.00 82.76  ? 876  VAL A CA  1 
ATOM   6176  C C   . VAL A 1 801 ? 9.796   0.394   36.533  1.00 84.40  ? 876  VAL A C   1 
ATOM   6177  O O   . VAL A 1 801 ? 8.621   0.103   36.280  1.00 89.71  ? 876  VAL A O   1 
ATOM   6178  C CB  . VAL A 1 801 ? 10.452  0.324   38.981  1.00 72.76  ? 876  VAL A CB  1 
ATOM   6179  C CG1 . VAL A 1 801 ? 9.004   0.390   39.431  1.00 76.69  ? 876  VAL A CG1 1 
ATOM   6180  C CG2 . VAL A 1 801 ? 11.301  -0.410  40.009  1.00 87.25  ? 876  VAL A CG2 1 
ATOM   6181  N N   . VAL A 1 802 ? 10.440  1.356   35.875  1.00 74.47  ? 877  VAL A N   1 
ATOM   6182  C CA  . VAL A 1 802 ? 9.838   2.104   34.781  1.00 75.98  ? 877  VAL A CA  1 
ATOM   6183  C C   . VAL A 1 802 ? 10.664  1.874   33.521  1.00 82.38  ? 877  VAL A C   1 
ATOM   6184  O O   . VAL A 1 802 ? 11.718  1.237   33.546  1.00 86.82  ? 877  VAL A O   1 
ATOM   6185  C CB  . VAL A 1 802 ? 9.726   3.610   35.086  1.00 72.32  ? 877  VAL A CB  1 
ATOM   6186  C CG1 . VAL A 1 802 ? 8.842   3.844   36.299  1.00 71.58  ? 877  VAL A CG1 1 
ATOM   6187  C CG2 . VAL A 1 802 ? 11.106  4.207   35.299  1.00 73.71  ? 877  VAL A CG2 1 
ATOM   6188  N N   . GLU A 1 803 ? 10.166  2.410   32.411  1.00 92.29  ? 878  GLU A N   1 
ATOM   6189  C CA  . GLU A 1 803 ? 10.864  2.287   31.140  1.00 91.75  ? 878  GLU A CA  1 
ATOM   6190  C C   . GLU A 1 803 ? 12.155  3.094   31.162  1.00 83.88  ? 878  GLU A C   1 
ATOM   6191  O O   . GLU A 1 803 ? 12.213  4.189   31.731  1.00 81.48  ? 878  GLU A O   1 
ATOM   6192  C CB  . GLU A 1 803 ? 9.968   2.761   29.995  1.00 109.40 ? 878  GLU A CB  1 
ATOM   6193  C CG  . GLU A 1 803 ? 8.761   1.871   29.718  1.00 110.11 ? 878  GLU A CG  1 
ATOM   6194  C CD  . GLU A 1 803 ? 9.147   0.504   29.179  1.00 110.84 ? 878  GLU A CD  1 
ATOM   6195  O OE1 . GLU A 1 803 ? 9.839   0.450   28.141  1.00 119.02 ? 878  GLU A OE1 1 
ATOM   6196  O OE2 . GLU A 1 803 ? 8.746   -0.515  29.782  1.00 106.81 ? 878  GLU A OE2 1 
ATOM   6197  N N   . MET A 1 804 ? 13.201  2.544   30.538  1.00 75.43  ? 879  MET A N   1 
ATOM   6198  C CA  . MET A 1 804 ? 14.456  3.278   30.416  1.00 81.01  ? 879  MET A CA  1 
ATOM   6199  C C   . MET A 1 804 ? 14.277  4.571   29.631  1.00 86.80  ? 879  MET A C   1 
ATOM   6200  O O   . MET A 1 804 ? 14.965  5.564   29.904  1.00 78.95  ? 879  MET A O   1 
ATOM   6201  C CB  . MET A 1 804 ? 15.519  2.407   29.746  1.00 90.80  ? 879  MET A CB  1 
ATOM   6202  C CG  . MET A 1 804 ? 16.929  2.965   29.873  1.00 93.30  ? 879  MET A CG  1 
ATOM   6203  S SD  . MET A 1 804 ? 18.225  1.713   29.925  1.00 102.99 ? 879  MET A SD  1 
ATOM   6204  C CE  . MET A 1 804 ? 17.492  0.498   31.017  1.00 99.84  ? 879  MET A CE  1 
ATOM   6205  N N   . ASN A 1 805 ? 13.352  4.579   28.667  1.00 91.69  ? 880  ASN A N   1 
ATOM   6206  C CA  . ASN A 1 805 ? 13.215  5.717   27.762  1.00 97.85  ? 880  ASN A CA  1 
ATOM   6207  C C   . ASN A 1 805 ? 12.891  7.005   28.504  1.00 95.58  ? 880  ASN A C   1 
ATOM   6208  O O   . ASN A 1 805 ? 13.343  8.082   28.095  1.00 101.98 ? 880  ASN A O   1 
ATOM   6209  C CB  . ASN A 1 805 ? 12.147  5.419   26.710  1.00 103.29 ? 880  ASN A CB  1 
ATOM   6210  C CG  . ASN A 1 805 ? 12.361  4.082   26.034  1.00 123.41 ? 880  ASN A CG  1 
ATOM   6211  O OD1 . ASN A 1 805 ? 13.477  3.756   25.626  1.00 168.77 ? 880  ASN A OD1 1 
ATOM   6212  N ND2 . ASN A 1 805 ? 11.297  3.299   25.914  1.00 123.91 ? 880  ASN A ND2 1 
ATOM   6213  N N   . THR A 1 806 ? 12.114  6.919   29.587  1.00 87.30  ? 881  THR A N   1 
ATOM   6214  C CA  . THR A 1 806 ? 11.854  8.090   30.417  1.00 89.75  ? 881  THR A CA  1 
ATOM   6215  C C   . THR A 1 806 ? 13.151  8.801   30.778  1.00 86.95  ? 881  THR A C   1 
ATOM   6216  O O   . THR A 1 806 ? 13.272  10.026  30.611  1.00 81.73  ? 881  THR A O   1 
ATOM   6217  C CB  . THR A 1 806 ? 11.111  7.673   31.684  1.00 78.44  ? 881  THR A CB  1 
ATOM   6218  O OG1 . THR A 1 806 ? 11.969  6.850   32.481  1.00 82.90  ? 881  THR A OG1 1 
ATOM   6219  C CG2 . THR A 1 806 ? 9.880   6.871   31.328  1.00 80.45  ? 881  THR A CG2 1 
ATOM   6220  N N   . ALA A 1 807 ? 14.150  8.031   31.234  1.00 82.34  ? 882  ALA A N   1 
ATOM   6221  C CA  . ALA A 1 807 ? 15.427  8.605   31.647  1.00 84.75  ? 882  ALA A CA  1 
ATOM   6222  C C   . ALA A 1 807 ? 15.984  9.578   30.621  1.00 86.81  ? 882  ALA A C   1 
ATOM   6223  O O   . ALA A 1 807 ? 16.744  10.480  30.990  1.00 91.47  ? 882  ALA A O   1 
ATOM   6224  C CB  . ALA A 1 807 ? 16.449  7.491   31.921  1.00 80.55  ? 882  ALA A CB  1 
ATOM   6225  N N   . ALA A 1 808 ? 15.599  9.433   29.345  1.00 79.33  ? 883  ALA A N   1 
ATOM   6226  C CA  . ALA A 1 808 ? 16.012  10.375  28.311  1.00 86.49  ? 883  ALA A CA  1 
ATOM   6227  C C   . ALA A 1 808 ? 15.938  11.811  28.807  1.00 88.61  ? 883  ALA A C   1 
ATOM   6228  O O   . ALA A 1 808 ? 16.947  12.528  28.820  1.00 105.06 ? 883  ALA A O   1 
ATOM   6229  C CB  . ALA A 1 808 ? 15.152  10.212  27.055  1.00 95.15  ? 883  ALA A CB  1 
ATOM   6230  N N   . ASP A 1 809 ? 14.754  12.232  29.265  1.00 79.84  ? 884  ASP A N   1 
ATOM   6231  C CA  . ASP A 1 809 ? 14.606  13.613  29.716  1.00 92.88  ? 884  ASP A CA  1 
ATOM   6232  C C   . ASP A 1 809 ? 15.592  13.934  30.830  1.00 94.65  ? 884  ASP A C   1 
ATOM   6233  O O   . ASP A 1 809 ? 16.306  14.942  30.765  1.00 113.59 ? 884  ASP A O   1 
ATOM   6234  C CB  . ASP A 1 809 ? 13.168  13.880  30.153  1.00 105.42 ? 884  ASP A CB  1 
ATOM   6235  C CG  . ASP A 1 809 ? 12.171  13.556  29.066  1.00 106.61 ? 884  ASP A CG  1 
ATOM   6236  O OD1 . ASP A 1 809 ? 12.612  13.366  27.912  1.00 110.18 ? 884  ASP A OD1 1 
ATOM   6237  O OD2 . ASP A 1 809 ? 10.958  13.522  29.347  1.00 106.11 ? 884  ASP A OD2 1 
ATOM   6238  N N   . ILE A 1 810 ? 15.682  13.065  31.840  1.00 81.85  ? 885  ILE A N   1 
ATOM   6239  C CA  . ILE A 1 810 ? 16.670  13.266  32.897  1.00 94.41  ? 885  ILE A CA  1 
ATOM   6240  C C   . ILE A 1 810 ? 18.061  13.431  32.295  1.00 85.78  ? 885  ILE A C   1 
ATOM   6241  O O   . ILE A 1 810 ? 18.789  14.380  32.616  1.00 85.71  ? 885  ILE A O   1 
ATOM   6242  C CB  . ILE A 1 810 ? 16.621  12.107  33.908  1.00 91.56  ? 885  ILE A CB  1 
ATOM   6243  C CG1 . ILE A 1 810 ? 15.332  12.167  34.725  1.00 76.53  ? 885  ILE A CG1 1 
ATOM   6244  C CG2 . ILE A 1 810 ? 17.826  12.163  34.832  1.00 104.29 ? 885  ILE A CG2 1 
ATOM   6245  C CD1 . ILE A 1 810 ? 14.242  11.266  34.202  1.00 80.42  ? 885  ILE A CD1 1 
ATOM   6246  N N   . PHE A 1 811 ? 18.430  12.539  31.371  1.00 78.45  ? 886  PHE A N   1 
ATOM   6247  C CA  . PHE A 1 811 ? 19.764  12.598  30.784  1.00 73.59  ? 886  PHE A CA  1 
ATOM   6248  C C   . PHE A 1 811 ? 19.989  13.896  30.017  1.00 76.10  ? 886  PHE A C   1 
ATOM   6249  O O   . PHE A 1 811 ? 21.130  14.361  29.913  1.00 90.43  ? 886  PHE A O   1 
ATOM   6250  C CB  . PHE A 1 811 ? 20.002  11.395  29.870  1.00 74.84  ? 886  PHE A CB  1 
ATOM   6251  C CG  . PHE A 1 811 ? 20.016  10.070  30.587  1.00 70.30  ? 886  PHE A CG  1 
ATOM   6252  C CD1 . PHE A 1 811 ? 20.070  10.010  31.973  1.00 77.53  ? 886  PHE A CD1 1 
ATOM   6253  C CD2 . PHE A 1 811 ? 19.994  8.885   29.872  1.00 71.12  ? 886  PHE A CD2 1 
ATOM   6254  C CE1 . PHE A 1 811 ? 20.085  8.791   32.628  1.00 79.14  ? 886  PHE A CE1 1 
ATOM   6255  C CE2 . PHE A 1 811 ? 20.013  7.663   30.522  1.00 71.61  ? 886  PHE A CE2 1 
ATOM   6256  C CZ  . PHE A 1 811 ? 20.059  7.617   31.902  1.00 73.01  ? 886  PHE A CZ  1 
ATOM   6257  N N   . LYS A 1 812 ? 18.926  14.505  29.481  1.00 78.91  ? 887  LYS A N   1 
ATOM   6258  C CA  . LYS A 1 812 ? 19.126  15.740  28.731  1.00 78.88  ? 887  LYS A CA  1 
ATOM   6259  C C   . LYS A 1 812 ? 19.504  16.899  29.643  1.00 86.06  ? 887  LYS A C   1 
ATOM   6260  O O   . LYS A 1 812 ? 19.984  17.926  29.153  1.00 87.34  ? 887  LYS A O   1 
ATOM   6261  C CB  . LYS A 1 812 ? 17.872  16.103  27.931  1.00 93.16  ? 887  LYS A CB  1 
ATOM   6262  C CG  . LYS A 1 812 ? 16.942  17.066  28.649  1.00 124.46 ? 887  LYS A CG  1 
ATOM   6263  C CD  . LYS A 1 812 ? 15.818  17.536  27.749  1.00 128.15 ? 887  LYS A CD  1 
ATOM   6264  C CE  . LYS A 1 812 ? 14.786  18.314  28.545  1.00 140.05 ? 887  LYS A CE  1 
ATOM   6265  N NZ  . LYS A 1 812 ? 14.067  17.442  29.511  1.00 144.49 ? 887  LYS A NZ  1 
ATOM   6266  N N   . GLN A 1 813 ? 19.305  16.758  30.955  1.00 92.37  ? 888  GLN A N   1 
ATOM   6267  C CA  . GLN A 1 813 ? 19.603  17.820  31.903  1.00 96.69  ? 888  GLN A CA  1 
ATOM   6268  C C   . GLN A 1 813 ? 20.916  17.584  32.637  1.00 89.98  ? 888  GLN A C   1 
ATOM   6269  O O   . GLN A 1 813 ? 21.189  18.256  33.638  1.00 98.28  ? 888  GLN A O   1 
ATOM   6270  C CB  . GLN A 1 813 ? 18.454  17.961  32.904  1.00 102.89 ? 888  GLN A CB  1 
ATOM   6271  C CG  . GLN A 1 813 ? 17.075  17.952  32.253  1.00 99.58  ? 888  GLN A CG  1 
ATOM   6272  C CD  . GLN A 1 813 ? 16.654  19.309  31.726  1.00 107.92 ? 888  GLN A CD  1 
ATOM   6273  O OE1 . GLN A 1 813 ? 17.324  19.891  30.873  1.00 109.17 ? 888  GLN A OE1 1 
ATOM   6274  N NE2 . GLN A 1 813 ? 15.529  19.813  32.219  1.00 117.14 ? 888  GLN A NE2 1 
ATOM   6275  N N   . TYR A 1 814 ? 21.733  16.646  32.151  1.00 84.98  ? 889  TYR A N   1 
ATOM   6276  C CA  . TYR A 1 814 ? 22.970  16.277  32.834  1.00 95.18  ? 889  TYR A CA  1 
ATOM   6277  C C   . TYR A 1 814 ? 23.925  17.461  32.942  1.00 105.43 ? 889  TYR A C   1 
ATOM   6278  O O   . TYR A 1 814 ? 24.418  17.777  34.031  1.00 105.01 ? 889  TYR A O   1 
ATOM   6279  C CB  . TYR A 1 814 ? 23.621  15.105  32.097  1.00 102.67 ? 889  TYR A CB  1 
ATOM   6280  C CG  . TYR A 1 814 ? 24.950  14.648  32.653  1.00 108.96 ? 889  TYR A CG  1 
ATOM   6281  C CD1 . TYR A 1 814 ? 25.121  14.412  34.011  1.00 103.46 ? 889  TYR A CD1 1 
ATOM   6282  C CD2 . TYR A 1 814 ? 26.032  14.438  31.810  1.00 108.44 ? 889  TYR A CD2 1 
ATOM   6283  C CE1 . TYR A 1 814 ? 26.339  13.987  34.511  1.00 112.97 ? 889  TYR A CE1 1 
ATOM   6284  C CE2 . TYR A 1 814 ? 27.248  14.015  32.299  1.00 119.22 ? 889  TYR A CE2 1 
ATOM   6285  C CZ  . TYR A 1 814 ? 27.398  13.791  33.648  1.00 118.98 ? 889  TYR A CZ  1 
ATOM   6286  O OH  . TYR A 1 814 ? 28.616  13.370  34.125  1.00 115.24 ? 889  TYR A OH  1 
ATOM   6287  N N   . MET A 1 815 ? 24.203  18.129  31.819  1.00 104.17 ? 890  MET A N   1 
ATOM   6288  C CA  . MET A 1 815 ? 25.025  19.334  31.862  1.00 106.22 ? 890  MET A CA  1 
ATOM   6289  C C   . MET A 1 815 ? 24.264  20.533  32.411  1.00 99.95  ? 890  MET A C   1 
ATOM   6290  O O   . MET A 1 815 ? 24.861  21.388  33.073  1.00 99.84  ? 890  MET A O   1 
ATOM   6291  C CB  . MET A 1 815 ? 25.556  19.662  30.467  1.00 124.99 ? 890  MET A CB  1 
ATOM   6292  C CG  . MET A 1 815 ? 26.917  20.342  30.459  1.00 142.79 ? 890  MET A CG  1 
ATOM   6293  S SD  . MET A 1 815 ? 27.671  20.330  28.821  1.00 153.17 ? 890  MET A SD  1 
ATOM   6294  C CE  . MET A 1 815 ? 26.296  20.892  27.825  1.00 113.12 ? 890  MET A CE  1 
ATOM   6295  N N   . LYS A 1 816 ? 22.959  20.611  32.149  1.00 95.55  ? 891  LYS A N   1 
ATOM   6296  C CA  . LYS A 1 816 ? 22.176  21.765  32.578  1.00 92.04  ? 891  LYS A CA  1 
ATOM   6297  C C   . LYS A 1 816 ? 22.138  21.881  34.096  1.00 97.33  ? 891  LYS A C   1 
ATOM   6298  O O   . LYS A 1 816 ? 22.159  22.990  34.642  1.00 110.26 ? 891  LYS A O   1 
ATOM   6299  C CB  . LYS A 1 816 ? 20.758  21.664  32.018  1.00 109.62 ? 891  LYS A CB  1 
ATOM   6300  C CG  . LYS A 1 816 ? 19.905  22.904  32.207  1.00 122.24 ? 891  LYS A CG  1 
ATOM   6301  C CD  . LYS A 1 816 ? 18.852  22.996  31.114  1.00 118.93 ? 891  LYS A CD  1 
ATOM   6302  C CE  . LYS A 1 816 ? 17.656  23.821  31.558  1.00 123.71 ? 891  LYS A CE  1 
ATOM   6303  N NZ  . LYS A 1 816 ? 16.519  22.965  31.999  1.00 134.64 ? 891  LYS A NZ  1 
ATOM   6304  N N   . TYR A 1 817 ? 22.071  20.750  34.793  1.00 103.57 ? 892  TYR A N   1 
ATOM   6305  C CA  . TYR A 1 817 ? 22.012  20.713  36.249  1.00 105.60 ? 892  TYR A CA  1 
ATOM   6306  C C   . TYR A 1 817 ? 23.141  19.863  36.818  1.00 101.46 ? 892  TYR A C   1 
ATOM   6307  O O   . TYR A 1 817 ? 22.929  19.048  37.719  1.00 97.89  ? 892  TYR A O   1 
ATOM   6308  C CB  . TYR A 1 817 ? 20.665  20.181  36.732  1.00 106.22 ? 892  TYR A CB  1 
ATOM   6309  C CG  . TYR A 1 817 ? 19.461  20.971  36.272  1.00 105.35 ? 892  TYR A CG  1 
ATOM   6310  C CD1 . TYR A 1 817 ? 18.827  20.668  35.074  1.00 100.73 ? 892  TYR A CD1 1 
ATOM   6311  C CD2 . TYR A 1 817 ? 18.949  22.009  37.039  1.00 108.45 ? 892  TYR A CD2 1 
ATOM   6312  C CE1 . TYR A 1 817 ? 17.723  21.378  34.650  1.00 101.68 ? 892  TYR A CE1 1 
ATOM   6313  C CE2 . TYR A 1 817 ? 17.842  22.728  36.621  1.00 108.22 ? 892  TYR A CE2 1 
ATOM   6314  C CZ  . TYR A 1 817 ? 17.234  22.407  35.426  1.00 101.19 ? 892  TYR A CZ  1 
ATOM   6315  O OH  . TYR A 1 817 ? 16.133  23.115  35.002  1.00 97.65  ? 892  TYR A OH  1 
ATOM   6316  N N   . TYR A 1 818 ? 24.356  20.039  36.290  1.00 104.77 ? 893  TYR A N   1 
ATOM   6317  C CA  . TYR A 1 818 ? 25.484  19.239  36.757  1.00 110.24 ? 893  TYR A CA  1 
ATOM   6318  C C   . TYR A 1 818 ? 25.700  19.427  38.254  1.00 105.93 ? 893  TYR A C   1 
ATOM   6319  O O   . TYR A 1 818 ? 25.835  18.450  38.996  1.00 91.02  ? 893  TYR A O   1 
ATOM   6320  C CB  . TYR A 1 818 ? 26.745  19.608  35.972  1.00 111.93 ? 893  TYR A CB  1 
ATOM   6321  C CG  . TYR A 1 818 ? 27.650  18.439  35.625  1.00 125.27 ? 893  TYR A CG  1 
ATOM   6322  C CD1 . TYR A 1 818 ? 28.276  17.690  36.615  1.00 113.35 ? 893  TYR A CD1 1 
ATOM   6323  C CD2 . TYR A 1 818 ? 27.877  18.088  34.299  1.00 161.29 ? 893  TYR A CD2 1 
ATOM   6324  C CE1 . TYR A 1 818 ? 29.104  16.625  36.291  1.00 107.88 ? 893  TYR A CE1 1 
ATOM   6325  C CE2 . TYR A 1 818 ? 28.699  17.029  33.967  1.00 158.27 ? 893  TYR A CE2 1 
ATOM   6326  C CZ  . TYR A 1 818 ? 29.310  16.301  34.964  1.00 139.22 ? 893  TYR A CZ  1 
ATOM   6327  O OH  . TYR A 1 818 ? 30.128  15.246  34.627  1.00 145.45 ? 893  TYR A OH  1 
ATOM   6328  N N   . ASN A 1 819 ? 25.669  20.673  38.724  1.00 104.75 ? 894  ASN A N   1 
ATOM   6329  C CA  . ASN A 1 819 ? 25.848  20.929  40.148  1.00 105.91 ? 894  ASN A CA  1 
ATOM   6330  C C   . ASN A 1 819 ? 24.641  20.459  40.952  1.00 105.00 ? 894  ASN A C   1 
ATOM   6331  O O   . ASN A 1 819 ? 24.791  19.796  41.985  1.00 122.57 ? 894  ASN A O   1 
ATOM   6332  C CB  . ASN A 1 819 ? 26.104  22.416  40.380  1.00 114.93 ? 894  ASN A CB  1 
ATOM   6333  C CG  . ASN A 1 819 ? 27.124  22.983  39.418  1.00 124.52 ? 894  ASN A CG  1 
ATOM   6334  O OD1 . ASN A 1 819 ? 26.782  23.401  38.312  1.00 144.20 ? 894  ASN A OD1 1 
ATOM   6335  N ND2 . ASN A 1 819 ? 28.384  23.005  39.834  1.00 129.30 ? 894  ASN A ND2 1 
ATOM   6336  N N   . ASP A 1 820 ? 23.434  20.785  40.487  1.00 97.80  ? 895  ASP A N   1 
ATOM   6337  C CA  . ASP A 1 820 ? 22.235  20.509  41.274  1.00 89.39  ? 895  ASP A CA  1 
ATOM   6338  C C   . ASP A 1 820 ? 21.927  19.017  41.326  1.00 86.01  ? 895  ASP A C   1 
ATOM   6339  O O   . ASP A 1 820 ? 21.689  18.461  42.405  1.00 83.41  ? 895  ASP A O   1 
ATOM   6340  C CB  . ASP A 1 820 ? 21.045  21.283  40.706  1.00 95.54  ? 895  ASP A CB  1 
ATOM   6341  C CG  . ASP A 1 820 ? 21.152  22.775  40.950  1.00 102.08 ? 895  ASP A CG  1 
ATOM   6342  O OD1 . ASP A 1 820 ? 22.179  23.215  41.509  1.00 97.64  ? 895  ASP A OD1 1 
ATOM   6343  O OD2 . ASP A 1 820 ? 20.208  23.506  40.586  1.00 108.67 ? 895  ASP A OD2 1 
ATOM   6344  N N   . TYR A 1 821 ? 21.918  18.348  40.170  1.00 88.71  ? 896  TYR A N   1 
ATOM   6345  C CA  . TYR A 1 821 ? 21.520  16.947  40.105  1.00 94.26  ? 896  TYR A CA  1 
ATOM   6346  C C   . TYR A 1 821 ? 22.474  16.076  39.295  1.00 85.49  ? 896  TYR A C   1 
ATOM   6347  O O   . TYR A 1 821 ? 22.118  14.933  38.970  1.00 78.00  ? 896  TYR A O   1 
ATOM   6348  C CB  . TYR A 1 821 ? 20.112  16.809  39.515  1.00 95.73  ? 896  TYR A CB  1 
ATOM   6349  C CG  . TYR A 1 821 ? 19.102  17.837  39.969  1.00 88.40  ? 896  TYR A CG  1 
ATOM   6350  C CD1 . TYR A 1 821 ? 18.632  17.849  41.274  1.00 86.87  ? 896  TYR A CD1 1 
ATOM   6351  C CD2 . TYR A 1 821 ? 18.591  18.773  39.080  1.00 78.21  ? 896  TYR A CD2 1 
ATOM   6352  C CE1 . TYR A 1 821 ? 17.698  18.781  41.688  1.00 89.01  ? 896  TYR A CE1 1 
ATOM   6353  C CE2 . TYR A 1 821 ? 17.659  19.708  39.483  1.00 83.92  ? 896  TYR A CE2 1 
ATOM   6354  C CZ  . TYR A 1 821 ? 17.215  19.708  40.788  1.00 86.34  ? 896  TYR A CZ  1 
ATOM   6355  O OH  . TYR A 1 821 ? 16.286  20.637  41.193  1.00 85.77  ? 896  TYR A OH  1 
ATOM   6356  N N   . GLY A 1 822 ? 23.663  16.578  38.952  1.00 89.75  ? 897  GLY A N   1 
ATOM   6357  C CA  . GLY A 1 822 ? 24.533  15.852  38.049  1.00 82.63  ? 897  GLY A CA  1 
ATOM   6358  C C   . GLY A 1 822 ? 25.022  14.537  38.614  1.00 82.18  ? 897  GLY A C   1 
ATOM   6359  O O   . GLY A 1 822 ? 25.209  13.576  37.870  1.00 80.45  ? 897  GLY A O   1 
ATOM   6360  N N   . ASP A 1 823 ? 25.227  14.468  39.930  1.00 91.35  ? 898  ASP A N   1 
ATOM   6361  C CA  . ASP A 1 823 ? 25.639  13.209  40.543  1.00 85.78  ? 898  ASP A CA  1 
ATOM   6362  C C   . ASP A 1 823 ? 24.566  12.143  40.361  1.00 85.24  ? 898  ASP A C   1 
ATOM   6363  O O   . ASP A 1 823 ? 24.857  11.002  39.978  1.00 80.70  ? 898  ASP A O   1 
ATOM   6364  C CB  . ASP A 1 823 ? 25.941  13.420  42.027  1.00 85.20  ? 898  ASP A CB  1 
ATOM   6365  C CG  . ASP A 1 823 ? 25.006  14.423  42.675  1.00 93.31  ? 898  ASP A CG  1 
ATOM   6366  O OD1 . ASP A 1 823 ? 25.203  14.738  43.868  1.00 90.92  ? 898  ASP A OD1 1 
ATOM   6367  O OD2 . ASP A 1 823 ? 24.069  14.888  41.993  1.00 104.28 ? 898  ASP A OD2 1 
ATOM   6368  N N   . ILE A 1 824 ? 23.309  12.506  40.628  1.00 88.42  ? 899  ILE A N   1 
ATOM   6369  C CA  . ILE A 1 824 ? 22.210  11.559  40.482  1.00 86.77  ? 899  ILE A CA  1 
ATOM   6370  C C   . ILE A 1 824 ? 22.051  11.147  39.025  1.00 87.74  ? 899  ILE A C   1 
ATOM   6371  O O   . ILE A 1 824 ? 21.849  9.964   38.719  1.00 81.14  ? 899  ILE A O   1 
ATOM   6372  C CB  . ILE A 1 824 ? 20.912  12.165  41.044  1.00 80.19  ? 899  ILE A CB  1 
ATOM   6373  C CG1 . ILE A 1 824 ? 21.130  12.637  42.481  1.00 69.37  ? 899  ILE A CG1 1 
ATOM   6374  C CG2 . ILE A 1 824 ? 19.784  11.149  40.988  1.00 68.28  ? 899  ILE A CG2 1 
ATOM   6375  C CD1 . ILE A 1 824 ? 20.409  13.919  42.815  1.00 71.28  ? 899  ILE A CD1 1 
ATOM   6376  N N   . ILE A 1 825 ? 22.144  12.110  38.103  1.00 81.22  ? 900  ILE A N   1 
ATOM   6377  C CA  . ILE A 1 825 ? 21.997  11.784  36.685  1.00 76.57  ? 900  ILE A CA  1 
ATOM   6378  C C   . ILE A 1 825 ? 23.139  10.884  36.226  1.00 83.63  ? 900  ILE A C   1 
ATOM   6379  O O   . ILE A 1 825 ? 22.936  9.950   35.441  1.00 89.61  ? 900  ILE A O   1 
ATOM   6380  C CB  . ILE A 1 825 ? 21.905  13.067  35.838  1.00 68.71  ? 900  ILE A CB  1 
ATOM   6381  C CG1 . ILE A 1 825 ? 20.748  13.943  36.321  1.00 63.01  ? 900  ILE A CG1 1 
ATOM   6382  C CG2 . ILE A 1 825 ? 21.730  12.724  34.365  1.00 65.19  ? 900  ILE A CG2 1 
ATOM   6383  C CD1 . ILE A 1 825 ? 20.821  15.379  35.844  1.00 72.91  ? 900  ILE A CD1 1 
ATOM   6384  N N   . LYS A 1 826 ? 24.349  11.133  36.730  1.00 78.17  ? 901  LYS A N   1 
ATOM   6385  C CA  . LYS A 1 826 ? 25.509  10.331  36.361  1.00 86.18  ? 901  LYS A CA  1 
ATOM   6386  C C   . LYS A 1 826 ? 25.361  8.898   36.854  1.00 84.78  ? 901  LYS A C   1 
ATOM   6387  O O   . LYS A 1 826 ? 25.619  7.940   36.113  1.00 83.82  ? 901  LYS A O   1 
ATOM   6388  C CB  . LYS A 1 826 ? 26.772  10.976  36.937  1.00 83.95  ? 901  LYS A CB  1 
ATOM   6389  C CG  . LYS A 1 826 ? 28.083  10.420  36.412  1.00 91.24  ? 901  LYS A CG  1 
ATOM   6390  C CD  . LYS A 1 826 ? 29.274  11.027  37.153  1.00 115.37 ? 901  LYS A CD  1 
ATOM   6391  C CE  . LYS A 1 826 ? 29.331  12.544  37.008  1.00 116.38 ? 901  LYS A CE  1 
ATOM   6392  N NZ  . LYS A 1 826 ? 29.398  13.241  38.323  1.00 108.23 ? 901  LYS A NZ  1 
ATOM   6393  N N   . GLU A 1 827 ? 24.951  8.734   38.115  1.00 82.71  ? 902  GLU A N   1 
ATOM   6394  C CA  . GLU A 1 827 ? 24.742  7.394   38.654  1.00 76.40  ? 902  GLU A CA  1 
ATOM   6395  C C   . GLU A 1 827 ? 23.638  6.663   37.901  1.00 81.49  ? 902  GLU A C   1 
ATOM   6396  O O   . GLU A 1 827 ? 23.777  5.475   37.583  1.00 86.55  ? 902  GLU A O   1 
ATOM   6397  C CB  . GLU A 1 827 ? 24.416  7.469   40.144  1.00 72.32  ? 902  GLU A CB  1 
ATOM   6398  C CG  . GLU A 1 827 ? 24.044  6.130   40.752  1.00 82.00  ? 902  GLU A CG  1 
ATOM   6399  C CD  . GLU A 1 827 ? 25.187  5.505   41.525  1.00 100.64 ? 902  GLU A CD  1 
ATOM   6400  O OE1 . GLU A 1 827 ? 26.310  5.449   40.980  1.00 95.13  ? 902  GLU A OE1 1 
ATOM   6401  O OE2 . GLU A 1 827 ? 24.961  5.073   42.675  1.00 107.08 ? 902  GLU A OE2 1 
ATOM   6402  N N   . THR A 1 828 ? 22.535  7.358   37.607  1.00 82.18  ? 903  THR A N   1 
ATOM   6403  C CA  . THR A 1 828 ? 21.456  6.759   36.827  1.00 84.49  ? 903  THR A CA  1 
ATOM   6404  C C   . THR A 1 828 ? 21.960  6.302   35.464  1.00 91.09  ? 903  THR A C   1 
ATOM   6405  O O   . THR A 1 828 ? 21.641  5.200   35.005  1.00 87.88  ? 903  THR A O   1 
ATOM   6406  C CB  . THR A 1 828 ? 20.314  7.764   36.661  1.00 76.55  ? 903  THR A CB  1 
ATOM   6407  O OG1 . THR A 1 828 ? 20.032  8.386   37.921  1.00 73.21  ? 903  THR A OG1 1 
ATOM   6408  C CG2 . THR A 1 828 ? 19.061  7.074   36.137  1.00 72.48  ? 903  THR A CG2 1 
ATOM   6409  N N   . MET A 1 829 ? 22.760  7.144   34.808  1.00 87.98  ? 904  MET A N   1 
ATOM   6410  C CA  . MET A 1 829 ? 23.257  6.834   33.474  1.00 83.15  ? 904  MET A CA  1 
ATOM   6411  C C   . MET A 1 829 ? 24.193  5.631   33.499  1.00 88.77  ? 904  MET A C   1 
ATOM   6412  O O   . MET A 1 829 ? 24.128  4.763   32.620  1.00 94.26  ? 904  MET A O   1 
ATOM   6413  C CB  . MET A 1 829 ? 23.947  8.074   32.906  1.00 70.97  ? 904  MET A CB  1 
ATOM   6414  C CG  . MET A 1 829 ? 24.499  7.952   31.507  1.00 96.20  ? 904  MET A CG  1 
ATOM   6415  S SD  . MET A 1 829 ? 24.866  9.590   30.841  1.00 111.60 ? 904  MET A SD  1 
ATOM   6416  C CE  . MET A 1 829 ? 25.194  10.520  32.340  1.00 73.87  ? 904  MET A CE  1 
ATOM   6417  N N   . SER A 1 830 ? 25.054  5.545   34.516  1.00 82.43  ? 905  SER A N   1 
ATOM   6418  C CA  . SER A 1 830 ? 25.951  4.397   34.628  1.00 89.38  ? 905  SER A CA  1 
ATOM   6419  C C   . SER A 1 830 ? 25.174  3.112   34.899  1.00 92.33  ? 905  SER A C   1 
ATOM   6420  O O   . SER A 1 830 ? 25.442  2.067   34.287  1.00 97.14  ? 905  SER A O   1 
ATOM   6421  C CB  . SER A 1 830 ? 26.985  4.647   35.726  1.00 82.65  ? 905  SER A CB  1 
ATOM   6422  O OG  . SER A 1 830 ? 26.394  4.569   37.010  1.00 106.06 ? 905  SER A OG  1 
ATOM   6423  N N   . LYS A 1 831 ? 24.208  3.168   35.821  1.00 93.34  ? 906  LYS A N   1 
ATOM   6424  C CA  . LYS A 1 831 ? 23.397  1.989   36.104  1.00 88.36  ? 906  LYS A CA  1 
ATOM   6425  C C   . LYS A 1 831 ? 22.632  1.539   34.866  1.00 88.08  ? 906  LYS A C   1 
ATOM   6426  O O   . LYS A 1 831 ? 22.523  0.336   34.601  1.00 88.61  ? 906  LYS A O   1 
ATOM   6427  C CB  . LYS A 1 831 ? 22.430  2.269   37.253  1.00 85.42  ? 906  LYS A CB  1 
ATOM   6428  C CG  . LYS A 1 831 ? 23.078  2.509   38.611  1.00 85.78  ? 906  LYS A CG  1 
ATOM   6429  C CD  . LYS A 1 831 ? 24.123  1.459   38.943  1.00 91.27  ? 906  LYS A CD  1 
ATOM   6430  C CE  . LYS A 1 831 ? 24.725  1.706   40.319  1.00 96.67  ? 906  LYS A CE  1 
ATOM   6431  N NZ  . LYS A 1 831 ? 26.014  2.449   40.252  1.00 109.74 ? 906  LYS A NZ  1 
ATOM   6432  N N   . THR A 1 832 ? 22.100  2.489   34.089  1.00 83.50  ? 907  THR A N   1 
ATOM   6433  C CA  . THR A 1 832 ? 21.379  2.125   32.873  1.00 91.90  ? 907  THR A CA  1 
ATOM   6434  C C   . THR A 1 832 ? 22.315  1.541   31.823  1.00 104.98 ? 907  THR A C   1 
ATOM   6435  O O   . THR A 1 832 ? 21.924  0.637   31.075  1.00 107.88 ? 907  THR A O   1 
ATOM   6436  C CB  . THR A 1 832 ? 20.631  3.335   32.313  1.00 87.53  ? 907  THR A CB  1 
ATOM   6437  O OG1 . THR A 1 832 ? 21.548  4.417   32.105  1.00 87.95  ? 907  THR A OG1 1 
ATOM   6438  C CG2 . THR A 1 832 ? 19.520  3.767   33.259  1.00 84.33  ? 907  THR A CG2 1 
ATOM   6439  N N   . ARG A 1 833 ? 23.546  2.054   31.736  1.00 103.07 ? 908  ARG A N   1 
ATOM   6440  C CA  . ARG A 1 833 ? 24.547  1.407   30.893  1.00 101.76 ? 908  ARG A CA  1 
ATOM   6441  C C   . ARG A 1 833 ? 24.712  -0.056  31.278  1.00 99.48  ? 908  ARG A C   1 
ATOM   6442  O O   . ARG A 1 833 ? 24.678  -0.947  30.422  1.00 105.71 ? 908  ARG A O   1 
ATOM   6443  C CB  . ARG A 1 833 ? 25.897  2.122   30.991  1.00 104.05 ? 908  ARG A CB  1 
ATOM   6444  C CG  . ARG A 1 833 ? 26.892  1.604   29.957  1.00 101.26 ? 908  ARG A CG  1 
ATOM   6445  C CD  . ARG A 1 833 ? 28.214  2.359   29.911  1.00 123.66 ? 908  ARG A CD  1 
ATOM   6446  N NE  . ARG A 1 833 ? 28.224  3.596   30.680  1.00 146.80 ? 908  ARG A NE  1 
ATOM   6447  C CZ  . ARG A 1 833 ? 28.819  3.740   31.856  1.00 140.61 ? 908  ARG A CZ  1 
ATOM   6448  N NH1 . ARG A 1 833 ? 29.411  2.722   32.460  1.00 127.09 ? 908  ARG A NH1 1 
ATOM   6449  N NH2 . ARG A 1 833 ? 28.827  4.936   32.437  1.00 147.35 ? 908  ARG A NH2 1 
ATOM   6450  N N   . GLN A 1 834 ? 24.888  -0.319  32.575  1.00 93.64  ? 909  GLN A N   1 
ATOM   6451  C CA  . GLN A 1 834 ? 25.081  -1.699  33.016  1.00 89.86  ? 909  GLN A CA  1 
ATOM   6452  C C   . GLN A 1 834 ? 23.854  -2.556  32.724  1.00 103.73 ? 909  GLN A C   1 
ATOM   6453  O O   . GLN A 1 834 ? 23.983  -3.733  32.366  1.00 113.68 ? 909  GLN A O   1 
ATOM   6454  C CB  . GLN A 1 834 ? 25.422  -1.745  34.503  1.00 99.82  ? 909  GLN A CB  1 
ATOM   6455  C CG  . GLN A 1 834 ? 26.675  -0.976  34.869  1.00 107.90 ? 909  GLN A CG  1 
ATOM   6456  C CD  . GLN A 1 834 ? 26.527  -0.217  36.168  1.00 119.16 ? 909  GLN A CD  1 
ATOM   6457  O OE1 . GLN A 1 834 ? 25.734  -0.591  37.032  1.00 146.51 ? 909  GLN A OE1 1 
ATOM   6458  N NE2 . GLN A 1 834 ? 27.297  0.854   36.317  1.00 119.18 ? 909  GLN A NE2 1 
ATOM   6459  N N   . ILE A 1 835 ? 22.656  -1.985  32.873  1.00 105.81 ? 910  ILE A N   1 
ATOM   6460  C CA  . ILE A 1 835 ? 21.429  -2.728  32.584  1.00 98.95  ? 910  ILE A CA  1 
ATOM   6461  C C   . ILE A 1 835 ? 21.396  -3.149  31.119  1.00 102.60 ? 910  ILE A C   1 
ATOM   6462  O O   . ILE A 1 835 ? 21.241  -4.332  30.795  1.00 100.95 ? 910  ILE A O   1 
ATOM   6463  C CB  . ILE A 1 835 ? 20.191  -1.891  32.952  1.00 103.11 ? 910  ILE A CB  1 
ATOM   6464  C CG1 . ILE A 1 835 ? 20.133  -1.640  34.460  1.00 96.24  ? 910  ILE A CG1 1 
ATOM   6465  C CG2 . ILE A 1 835 ? 18.922  -2.584  32.484  1.00 112.26 ? 910  ILE A CG2 1 
ATOM   6466  C CD1 . ILE A 1 835 ? 20.069  -2.901  35.287  1.00 96.91  ? 910  ILE A CD1 1 
ATOM   6467  N N   . ASP A 1 836 ? 21.543  -2.181  30.211  1.00 104.40 ? 911  ASP A N   1 
ATOM   6468  C CA  . ASP A 1 836 ? 21.494  -2.464  28.777  1.00 109.43 ? 911  ASP A CA  1 
ATOM   6469  C C   . ASP A 1 836 ? 22.233  -1.333  28.063  1.00 108.75 ? 911  ASP A C   1 
ATOM   6470  O O   . ASP A 1 836 ? 21.688  -0.237  27.913  1.00 111.62 ? 911  ASP A O   1 
ATOM   6471  C CB  . ASP A 1 836 ? 20.058  -2.588  28.291  1.00 108.12 ? 911  ASP A CB  1 
ATOM   6472  C CG  . ASP A 1 836 ? 19.937  -3.438  27.044  1.00 107.95 ? 911  ASP A CG  1 
ATOM   6473  O OD1 . ASP A 1 836 ? 20.905  -4.158  26.720  1.00 121.45 ? 911  ASP A OD1 1 
ATOM   6474  O OD2 . ASP A 1 836 ? 18.873  -3.389  26.391  1.00 100.57 ? 911  ASP A OD2 1 
ATOM   6475  N N   . LYS A 1 837 ? 23.467  -1.612  27.631  1.00 105.26 ? 912  LYS A N   1 
ATOM   6476  C CA  . LYS A 1 837 ? 24.276  -0.576  26.996  1.00 114.08 ? 912  LYS A CA  1 
ATOM   6477  C C   . LYS A 1 837 ? 23.657  -0.112  25.683  1.00 117.74 ? 912  LYS A C   1 
ATOM   6478  O O   . LYS A 1 837 ? 23.691  1.081   25.361  1.00 113.32 ? 912  LYS A O   1 
ATOM   6479  C CB  . LYS A 1 837 ? 25.703  -1.078  26.769  1.00 104.36 ? 912  LYS A CB  1 
ATOM   6480  C CG  . LYS A 1 837 ? 26.162  -2.164  27.728  1.00 129.85 ? 912  LYS A CG  1 
ATOM   6481  C CD  . LYS A 1 837 ? 27.608  -2.548  27.458  1.00 140.92 ? 912  LYS A CD  1 
ATOM   6482  C CE  . LYS A 1 837 ? 28.159  -3.460  28.541  1.00 137.94 ? 912  LYS A CE  1 
ATOM   6483  N NZ  . LYS A 1 837 ? 27.288  -4.645  28.772  1.00 150.95 ? 912  LYS A NZ  1 
ATOM   6484  N N   . ILE A 1 838 ? 23.083  -1.038  24.915  1.00 119.80 ? 913  ILE A N   1 
ATOM   6485  C CA  . ILE A 1 838 ? 22.475  -0.671  23.640  1.00 117.09 ? 913  ILE A CA  1 
ATOM   6486  C C   . ILE A 1 838 ? 21.263  0.232   23.864  1.00 112.57 ? 913  ILE A C   1 
ATOM   6487  O O   . ILE A 1 838 ? 21.123  1.287   23.225  1.00 106.44 ? 913  ILE A O   1 
ATOM   6488  C CB  . ILE A 1 838 ? 22.136  -1.949  22.846  1.00 110.67 ? 913  ILE A CB  1 
ATOM   6489  C CG1 . ILE A 1 838 ? 21.554  -1.620  21.470  1.00 146.50 ? 913  ILE A CG1 1 
ATOM   6490  C CG2 . ILE A 1 838 ? 21.234  -2.889  23.648  1.00 107.08 ? 913  ILE A CG2 1 
ATOM   6491  C CD1 . ILE A 1 838 ? 22.068  -2.535  20.380  1.00 162.34 ? 913  ILE A CD1 1 
ATOM   6492  N N   . GLN A 1 839 ? 20.398  -0.134  24.811  1.00 112.58 ? 914  GLN A N   1 
ATOM   6493  C CA  . GLN A 1 839 ? 19.233  0.689   25.110  1.00 107.41 ? 914  GLN A CA  1 
ATOM   6494  C C   . GLN A 1 839 ? 19.628  2.002   25.775  1.00 105.53 ? 914  GLN A C   1 
ATOM   6495  O O   . GLN A 1 839 ? 18.975  3.026   25.551  1.00 103.91 ? 914  GLN A O   1 
ATOM   6496  C CB  . GLN A 1 839 ? 18.262  -0.098  25.989  1.00 102.80 ? 914  GLN A CB  1 
ATOM   6497  C CG  . GLN A 1 839 ? 16.905  0.548   26.159  1.00 109.17 ? 914  GLN A CG  1 
ATOM   6498  C CD  . GLN A 1 839 ? 16.009  -0.242  27.085  1.00 112.74 ? 914  GLN A CD  1 
ATOM   6499  O OE1 . GLN A 1 839 ? 16.454  -1.185  27.737  1.00 111.53 ? 914  GLN A OE1 1 
ATOM   6500  N NE2 . GLN A 1 839 ? 14.735  0.128   27.139  1.00 111.39 ? 914  GLN A NE2 1 
ATOM   6501  N N   . CYS A 1 840 ? 20.693  1.999   26.578  1.00 101.69 ? 915  CYS A N   1 
ATOM   6502  C CA  . CYS A 1 840 ? 21.186  3.247   27.153  1.00 97.77  ? 915  CYS A CA  1 
ATOM   6503  C C   . CYS A 1 840 ? 21.702  4.188   26.071  1.00 96.53  ? 915  CYS A C   1 
ATOM   6504  O O   . CYS A 1 840 ? 21.489  5.407   26.139  1.00 95.09  ? 915  CYS A O   1 
ATOM   6505  C CB  . CYS A 1 840 ? 22.284  2.957   28.176  1.00 86.76  ? 915  CYS A CB  1 
ATOM   6506  S SG  . CYS A 1 840 ? 22.991  4.431   28.948  1.00 93.32  ? 915  CYS A SG  1 
ATOM   6507  N N   . ALA A 1 841 ? 22.388  3.642   25.065  1.00 92.59  ? 916  ALA A N   1 
ATOM   6508  C CA  . ALA A 1 841 ? 22.806  4.458   23.931  1.00 98.00  ? 916  ALA A CA  1 
ATOM   6509  C C   . ALA A 1 841 ? 21.599  5.017   23.190  1.00 100.31 ? 916  ALA A C   1 
ATOM   6510  O O   . ALA A 1 841 ? 21.602  6.181   22.763  1.00 98.29  ? 916  ALA A O   1 
ATOM   6511  C CB  . ALA A 1 841 ? 23.689  3.637   22.991  1.00 101.47 ? 916  ALA A CB  1 
ATOM   6512  N N   . LYS A 1 842 ? 20.552  4.203   23.031  1.00 92.58  ? 917  LYS A N   1 
ATOM   6513  C CA  . LYS A 1 842 ? 19.333  4.709   22.405  1.00 91.28  ? 917  LYS A CA  1 
ATOM   6514  C C   . LYS A 1 842 ? 18.731  5.858   23.209  1.00 101.71 ? 917  LYS A C   1 
ATOM   6515  O O   . LYS A 1 842 ? 18.323  6.876   22.640  1.00 102.12 ? 917  LYS A O   1 
ATOM   6516  C CB  . LYS A 1 842 ? 18.313  3.587   22.222  1.00 97.22  ? 917  LYS A CB  1 
ATOM   6517  C CG  . LYS A 1 842 ? 18.608  2.645   21.066  1.00 104.67 ? 917  LYS A CG  1 
ATOM   6518  C CD  . LYS A 1 842 ? 17.633  1.482   21.089  1.00 110.20 ? 917  LYS A CD  1 
ATOM   6519  C CE  . LYS A 1 842 ? 17.731  0.635   19.837  1.00 103.49 ? 917  LYS A CE  1 
ATOM   6520  N NZ  . LYS A 1 842 ? 17.502  1.439   18.607  1.00 111.95 ? 917  LYS A NZ  1 
ATOM   6521  N N   . THR A 1 843 ? 18.677  5.726   24.533  1.00 88.79  ? 918  THR A N   1 
ATOM   6522  C CA  . THR A 1 843 ? 18.095  6.797   25.342  1.00 92.03  ? 918  THR A CA  1 
ATOM   6523  C C   . THR A 1 843 ? 18.950  8.062   25.305  1.00 101.01 ? 918  THR A C   1 
ATOM   6524  O O   . THR A 1 843 ? 18.418  9.181   25.335  1.00 97.60  ? 918  THR A O   1 
ATOM   6525  C CB  . THR A 1 843 ? 17.900  6.328   26.779  1.00 83.84  ? 918  THR A CB  1 
ATOM   6526  O OG1 . THR A 1 843 ? 19.181  6.087   27.377  1.00 103.70 ? 918  THR A OG1 1 
ATOM   6527  C CG2 . THR A 1 843 ? 17.048  5.066   26.817  1.00 94.61  ? 918  THR A CG2 1 
ATOM   6528  N N   . LEU A 1 844 ? 20.274  7.910   25.234  1.00 95.84  ? 919  LEU A N   1 
ATOM   6529  C CA  . LEU A 1 844 ? 21.139  9.081   25.121  1.00 90.75  ? 919  LEU A CA  1 
ATOM   6530  C C   . LEU A 1 844 ? 20.937  9.788   23.784  1.00 90.80  ? 919  LEU A C   1 
ATOM   6531  O O   . LEU A 1 844 ? 20.900  11.028  23.720  1.00 85.43  ? 919  LEU A O   1 
ATOM   6532  C CB  . LEU A 1 844 ? 22.600  8.670   25.305  1.00 93.35  ? 919  LEU A CB  1 
ATOM   6533  C CG  . LEU A 1 844 ? 23.048  8.359   26.738  1.00 84.68  ? 919  LEU A CG  1 
ATOM   6534  C CD1 . LEU A 1 844 ? 24.521  7.987   26.785  1.00 99.70  ? 919  LEU A CD1 1 
ATOM   6535  C CD2 . LEU A 1 844 ? 22.774  9.536   27.656  1.00 93.75  ? 919  LEU A CD2 1 
ATOM   6536  N N   . ILE A 1 845 ? 20.804  9.017   22.702  1.00 92.36  ? 920  ILE A N   1 
ATOM   6537  C CA  . ILE A 1 845 ? 20.548  9.641   21.408  1.00 106.54 ? 920  ILE A CA  1 
ATOM   6538  C C   . ILE A 1 845 ? 19.177  10.302  21.415  1.00 106.38 ? 920  ILE A C   1 
ATOM   6539  O O   . ILE A 1 845 ? 18.973  11.331  20.762  1.00 102.15 ? 920  ILE A O   1 
ATOM   6540  C CB  . ILE A 1 845 ? 20.693  8.618   20.263  1.00 114.27 ? 920  ILE A CB  1 
ATOM   6541  C CG1 . ILE A 1 845 ? 20.897  9.340   18.935  1.00 121.36 ? 920  ILE A CG1 1 
ATOM   6542  C CG2 . ILE A 1 845 ? 19.465  7.719   20.154  1.00 110.04 ? 920  ILE A CG2 1 
ATOM   6543  C CD1 . ILE A 1 845 ? 22.049  10.309  18.951  1.00 109.86 ? 920  ILE A CD1 1 
ATOM   6544  N N   . LEU A 1 846 ? 18.229  9.748   22.174  1.00 96.78  ? 921  LEU A N   1 
ATOM   6545  C CA  . LEU A 1 846 ? 16.930  10.398  22.306  1.00 85.06  ? 921  LEU A CA  1 
ATOM   6546  C C   . LEU A 1 846 ? 17.052  11.729  23.034  1.00 86.76  ? 921  LEU A C   1 
ATOM   6547  O O   . LEU A 1 846 ? 16.402  12.709  22.658  1.00 86.93  ? 921  LEU A O   1 
ATOM   6548  C CB  . LEU A 1 846 ? 15.937  9.491   23.035  1.00 82.97  ? 921  LEU A CB  1 
ATOM   6549  C CG  . LEU A 1 846 ? 15.474  8.219   22.330  1.00 88.41  ? 921  LEU A CG  1 
ATOM   6550  C CD1 . LEU A 1 846 ? 14.867  7.251   23.328  1.00 91.11  ? 921  LEU A CD1 1 
ATOM   6551  C CD2 . LEU A 1 846 ? 14.477  8.564   21.244  1.00 95.04  ? 921  LEU A CD2 1 
ATOM   6552  N N   . SER A 1 847 ? 17.870  11.781  24.087  1.00 82.32  ? 922  SER A N   1 
ATOM   6553  C CA  . SER A 1 847 ? 18.079  13.048  24.783  1.00 93.33  ? 922  SER A CA  1 
ATOM   6554  C C   . SER A 1 847 ? 18.696  14.092  23.856  1.00 98.66  ? 922  SER A C   1 
ATOM   6555  O O   . SER A 1 847 ? 18.264  15.253  23.833  1.00 96.42  ? 922  SER A O   1 
ATOM   6556  C CB  . SER A 1 847 ? 18.958  12.832  26.016  1.00 91.26  ? 922  SER A CB  1 
ATOM   6557  O OG  . SER A 1 847 ? 18.697  11.580  26.624  1.00 93.08  ? 922  SER A OG  1 
ATOM   6558  N N   . LEU A 1 848 ? 19.704  13.694  23.075  1.00 96.73  ? 923  LEU A N   1 
ATOM   6559  C CA  . LEU A 1 848 ? 20.313  14.643  22.144  1.00 97.82  ? 923  LEU A CA  1 
ATOM   6560  C C   . LEU A 1 848 ? 19.321  15.094  21.077  1.00 110.55 ? 923  LEU A C   1 
ATOM   6561  O O   . LEU A 1 848 ? 19.285  16.276  20.711  1.00 111.73 ? 923  LEU A O   1 
ATOM   6562  C CB  . LEU A 1 848 ? 21.551  14.035  21.496  1.00 105.93 ? 923  LEU A CB  1 
ATOM   6563  C CG  . LEU A 1 848 ? 22.669  13.655  22.459  1.00 105.55 ? 923  LEU A CG  1 
ATOM   6564  C CD1 . LEU A 1 848 ? 23.533  12.596  21.821  1.00 102.99 ? 923  LEU A CD1 1 
ATOM   6565  C CD2 . LEU A 1 848 ? 23.491  14.878  22.828  1.00 103.87 ? 923  LEU A CD2 1 
ATOM   6566  N N   . GLN A 1 849 ? 18.508  14.168  20.563  1.00 106.76 ? 924  GLN A N   1 
ATOM   6567  C CA  . GLN A 1 849 ? 17.494  14.536  19.583  1.00 101.38 ? 924  GLN A CA  1 
ATOM   6568  C C   . GLN A 1 849 ? 16.490  15.509  20.187  1.00 110.11 ? 924  GLN A C   1 
ATOM   6569  O O   . GLN A 1 849 ? 16.030  16.442  19.515  1.00 117.99 ? 924  GLN A O   1 
ATOM   6570  C CB  . GLN A 1 849 ? 16.787  13.275  19.088  1.00 99.78  ? 924  GLN A CB  1 
ATOM   6571  C CG  . GLN A 1 849 ? 17.598  12.457  18.093  1.00 100.74 ? 924  GLN A CG  1 
ATOM   6572  C CD  . GLN A 1 849 ? 17.118  11.023  18.003  1.00 97.22  ? 924  GLN A CD  1 
ATOM   6573  O OE1 . GLN A 1 849 ? 16.225  10.612  18.741  1.00 99.60  ? 924  GLN A OE1 1 
ATOM   6574  N NE2 . GLN A 1 849 ? 17.730  10.245  17.121  1.00 112.35 ? 924  GLN A NE2 1 
ATOM   6575  N N   . GLN A 1 850 ? 16.127  15.288  21.455  1.00 101.30 ? 925  GLN A N   1 
ATOM   6576  C CA  . GLN A 1 850 ? 15.213  16.181  22.158  1.00 103.22 ? 925  GLN A CA  1 
ATOM   6577  C C   . GLN A 1 850 ? 15.803  17.579  22.277  1.00 112.99 ? 925  GLN A C   1 
ATOM   6578  O O   . GLN A 1 850 ? 15.101  18.584  22.095  1.00 115.85 ? 925  GLN A O   1 
ATOM   6579  C CB  . GLN A 1 850 ? 14.893  15.602  23.539  1.00 99.00  ? 925  GLN A CB  1 
ATOM   6580  C CG  . GLN A 1 850 ? 13.946  16.430  24.384  1.00 119.71 ? 925  GLN A CG  1 
ATOM   6581  C CD  . GLN A 1 850 ? 13.723  15.805  25.749  1.00 123.75 ? 925  GLN A CD  1 
ATOM   6582  O OE1 . GLN A 1 850 ? 14.566  15.055  26.244  1.00 116.13 ? 925  GLN A OE1 1 
ATOM   6583  N NE2 . GLN A 1 850 ? 12.589  16.111  26.367  1.00 127.21 ? 925  GLN A NE2 1 
ATOM   6584  N N   . LEU A 1 851 ? 17.103  17.664  22.564  1.00 112.98 ? 926  LEU A N   1 
ATOM   6585  C CA  . LEU A 1 851 ? 17.742  18.976  22.597  1.00 113.00 ? 926  LEU A CA  1 
ATOM   6586  C C   . LEU A 1 851 ? 17.747  19.612  21.215  1.00 115.51 ? 926  LEU A C   1 
ATOM   6587  O O   . LEU A 1 851 ? 17.514  20.818  21.080  1.00 116.56 ? 926  LEU A O   1 
ATOM   6588  C CB  . LEU A 1 851 ? 19.156  18.875  23.163  1.00 112.17 ? 926  LEU A CB  1 
ATOM   6589  C CG  . LEU A 1 851 ? 19.219  18.411  24.613  1.00 106.98 ? 926  LEU A CG  1 
ATOM   6590  C CD1 . LEU A 1 851 ? 20.565  17.788  24.884  1.00 112.71 ? 926  LEU A CD1 1 
ATOM   6591  C CD2 . LEU A 1 851 ? 18.952  19.572  25.560  1.00 90.63  ? 926  LEU A CD2 1 
ATOM   6592  N N   . PHE A 1 852 ? 17.956  18.806  20.173  1.00 111.55 ? 927  PHE A N   1 
ATOM   6593  C CA  . PHE A 1 852 ? 17.989  19.337  18.813  1.00 115.65 ? 927  PHE A CA  1 
ATOM   6594  C C   . PHE A 1 852 ? 16.644  19.942  18.416  1.00 123.66 ? 927  PHE A C   1 
ATOM   6595  O O   . PHE A 1 852 ? 16.576  21.087  17.944  1.00 128.68 ? 927  PHE A O   1 
ATOM   6596  C CB  . PHE A 1 852 ? 18.398  18.235  17.833  1.00 119.58 ? 927  PHE A CB  1 
ATOM   6597  C CG  . PHE A 1 852 ? 18.801  18.746  16.475  1.00 127.63 ? 927  PHE A CG  1 
ATOM   6598  C CD1 . PHE A 1 852 ? 20.010  19.402  16.289  1.00 140.66 ? 927  PHE A CD1 1 
ATOM   6599  C CD2 . PHE A 1 852 ? 17.964  18.579  15.385  1.00 124.02 ? 927  PHE A CD2 1 
ATOM   6600  C CE1 . PHE A 1 852 ? 20.381  19.868  15.038  1.00 144.52 ? 927  PHE A CE1 1 
ATOM   6601  C CE2 . PHE A 1 852 ? 18.326  19.046  14.136  1.00 137.81 ? 927  PHE A CE2 1 
ATOM   6602  C CZ  . PHE A 1 852 ? 19.535  19.691  13.961  1.00 147.40 ? 927  PHE A CZ  1 
ATOM   6603  N N   . ASN A 1 853 ? 15.555  19.190  18.591  1.00 122.19 ? 928  ASN A N   1 
ATOM   6604  C CA  . ASN A 1 853 ? 14.292  19.739  18.108  1.00 121.83 ? 928  ASN A CA  1 
ATOM   6605  C C   . ASN A 1 853 ? 13.786  20.825  19.049  1.00 122.99 ? 928  ASN A C   1 
ATOM   6606  O O   . ASN A 1 853 ? 13.054  21.722  18.617  1.00 129.88 ? 928  ASN A O   1 
ATOM   6607  C CB  . ASN A 1 853 ? 13.226  18.656  17.915  1.00 107.93 ? 928  ASN A CB  1 
ATOM   6608  C CG  . ASN A 1 853 ? 13.324  17.538  18.922  1.00 124.66 ? 928  ASN A CG  1 
ATOM   6609  O OD1 . ASN A 1 853 ? 13.443  17.781  20.113  1.00 148.12 ? 928  ASN A OD1 1 
ATOM   6610  N ND2 . ASN A 1 853 ? 13.339  16.307  18.443  1.00 119.92 ? 928  ASN A ND2 1 
ATOM   6611  N N   . GLU A 1 854 ? 14.210  20.805  20.321  1.00 118.59 ? 929  GLU A N   1 
ATOM   6612  C CA  . GLU A 1 854 ? 13.930  21.946  21.183  1.00 122.37 ? 929  GLU A CA  1 
ATOM   6613  C C   . GLU A 1 854 ? 14.650  23.196  20.693  1.00 129.81 ? 929  GLU A C   1 
ATOM   6614  O O   . GLU A 1 854 ? 14.103  24.302  20.767  1.00 135.46 ? 929  GLU A O   1 
ATOM   6615  C CB  . GLU A 1 854 ? 14.320  21.631  22.626  1.00 124.68 ? 929  GLU A CB  1 
ATOM   6616  C CG  . GLU A 1 854 ? 13.315  20.771  23.374  1.00 130.95 ? 929  GLU A CG  1 
ATOM   6617  C CD  . GLU A 1 854 ? 13.922  20.085  24.582  1.00 135.00 ? 929  GLU A CD  1 
ATOM   6618  O OE1 . GLU A 1 854 ? 15.166  20.029  24.667  1.00 134.87 ? 929  GLU A OE1 1 
ATOM   6619  O OE2 . GLU A 1 854 ? 13.159  19.589  25.440  1.00 135.41 ? 929  GLU A OE2 1 
ATOM   6620  N N   . MET A 1 855 ? 15.880  23.042  20.198  1.00 130.41 ? 930  MET A N   1 
ATOM   6621  C CA  . MET A 1 855 ? 16.599  24.178  19.628  1.00 123.25 ? 930  MET A CA  1 
ATOM   6622  C C   . MET A 1 855 ? 15.880  24.719  18.400  1.00 130.47 ? 930  MET A C   1 
ATOM   6623  O O   . MET A 1 855 ? 15.707  25.935  18.251  1.00 133.75 ? 930  MET A O   1 
ATOM   6624  C CB  . MET A 1 855 ? 18.028  23.769  19.275  1.00 120.22 ? 930  MET A CB  1 
ATOM   6625  C CG  . MET A 1 855 ? 18.929  24.936  18.917  1.00 130.34 ? 930  MET A CG  1 
ATOM   6626  S SD  . MET A 1 855 ? 20.462  24.416  18.120  1.00 155.27 ? 930  MET A SD  1 
ATOM   6627  C CE  . MET A 1 855 ? 19.988  22.820  17.458  1.00 130.99 ? 930  MET A CE  1 
ATOM   6628  N N   . ILE A 1 856 ? 15.457  23.826  17.504  1.00 133.76 ? 931  ILE A N   1 
ATOM   6629  C CA  . ILE A 1 856 ? 14.752  24.292  16.311  1.00 138.34 ? 931  ILE A CA  1 
ATOM   6630  C C   . ILE A 1 856 ? 13.399  24.899  16.676  1.00 141.87 ? 931  ILE A C   1 
ATOM   6631  O O   . ILE A 1 856 ? 12.865  25.730  15.931  1.00 143.63 ? 931  ILE A O   1 
ATOM   6632  C CB  . ILE A 1 856 ? 14.605  23.161  15.275  1.00 135.63 ? 931  ILE A CB  1 
ATOM   6633  C CG1 . ILE A 1 856 ? 13.382  22.298  15.589  1.00 135.06 ? 931  ILE A CG1 1 
ATOM   6634  C CG2 . ILE A 1 856 ? 15.886  22.341  15.184  1.00 128.72 ? 931  ILE A CG2 1 
ATOM   6635  C CD1 . ILE A 1 856 ? 13.299  21.034  14.782  1.00 136.19 ? 931  ILE A CD1 1 
ATOM   6636  N N   . GLN A 1 857 ? 12.825  24.510  17.818  1.00 139.33 ? 932  GLN A N   1 
ATOM   6637  C CA  . GLN A 1 857 ? 11.572  25.117  18.258  1.00 130.32 ? 932  GLN A CA  1 
ATOM   6638  C C   . GLN A 1 857 ? 11.796  26.503  18.854  1.00 140.28 ? 932  GLN A C   1 
ATOM   6639  O O   . GLN A 1 857 ? 11.003  27.419  18.612  1.00 151.78 ? 932  GLN A O   1 
ATOM   6640  C CB  . GLN A 1 857 ? 10.878  24.207  19.272  1.00 132.87 ? 932  GLN A CB  1 
ATOM   6641  C CG  . GLN A 1 857 ? 10.079  23.070  18.649  1.00 143.15 ? 932  GLN A CG  1 
ATOM   6642  C CD  . GLN A 1 857 ? 10.217  21.768  19.416  1.00 145.02 ? 932  GLN A CD  1 
ATOM   6643  O OE1 . GLN A 1 857 ? 10.243  21.757  20.646  1.00 143.26 ? 932  GLN A OE1 1 
ATOM   6644  N NE2 . GLN A 1 857 ? 10.314  20.661  18.688  1.00 144.50 ? 932  GLN A NE2 1 
ATOM   6645  N N   . GLU A 1 858 ? 12.868  26.672  19.633  1.00 151.85 ? 933  GLU A N   1 
ATOM   6646  C CA  . GLU A 1 858 ? 13.164  27.978  20.215  1.00 158.28 ? 933  GLU A CA  1 
ATOM   6647  C C   . GLU A 1 858 ? 13.676  28.949  19.159  1.00 154.33 ? 933  GLU A C   1 
ATOM   6648  O O   . GLU A 1 858 ? 13.240  30.106  19.103  1.00 165.82 ? 933  GLU A O   1 
ATOM   6649  C CB  . GLU A 1 858 ? 14.195  27.839  21.338  1.00 155.35 ? 933  GLU A CB  1 
ATOM   6650  C CG  . GLU A 1 858 ? 13.809  26.897  22.471  1.00 154.80 ? 933  GLU A CG  1 
ATOM   6651  C CD  . GLU A 1 858 ? 12.322  26.888  22.759  1.00 156.93 ? 933  GLU A CD  1 
ATOM   6652  O OE1 . GLU A 1 858 ? 11.826  27.869  23.351  1.00 157.87 ? 933  GLU A OE1 1 
ATOM   6653  O OE2 . GLU A 1 858 ? 11.651  25.895  22.407  1.00 172.82 ? 933  GLU A OE2 1 
ATOM   6654  N N   . ASN A 1 859 ? 14.603  28.499  18.320  1.00 140.51 ? 934  ASN A N   1 
ATOM   6655  C CA  . ASN A 1 859 ? 15.243  29.342  17.325  1.00 155.12 ? 934  ASN A CA  1 
ATOM   6656  C C   . ASN A 1 859 ? 15.103  28.689  15.958  1.00 163.59 ? 934  ASN A C   1 
ATOM   6657  O O   . ASN A 1 859 ? 15.072  27.462  15.842  1.00 159.49 ? 934  ASN A O   1 
ATOM   6658  C CB  . ASN A 1 859 ? 16.724  29.566  17.672  1.00 156.72 ? 934  ASN A CB  1 
ATOM   6659  C CG  . ASN A 1 859 ? 17.425  30.481  16.691  1.00 166.61 ? 934  ASN A CG  1 
ATOM   6660  O OD1 . ASN A 1 859 ? 18.278  30.046  15.918  1.00 166.02 ? 934  ASN A OD1 1 
ATOM   6661  N ND2 . ASN A 1 859 ? 17.077  31.762  16.726  1.00 167.65 ? 934  ASN A ND2 1 
ATOM   6662  N N   . GLY A 1 860 ? 15.014  29.521  14.922  1.00 169.42 ? 935  GLY A N   1 
ATOM   6663  C CA  . GLY A 1 860 ? 14.797  29.009  13.582  1.00 160.96 ? 935  GLY A CA  1 
ATOM   6664  C C   . GLY A 1 860 ? 15.914  28.092  13.120  1.00 163.47 ? 935  GLY A C   1 
ATOM   6665  O O   . GLY A 1 860 ? 17.004  28.048  13.693  1.00 181.53 ? 935  GLY A O   1 
ATOM   6666  N N   . TYR A 1 861 ? 15.633  27.355  12.042  1.00 154.97 ? 936  TYR A N   1 
ATOM   6667  C CA  . TYR A 1 861 ? 16.593  26.418  11.462  1.00 154.76 ? 936  TYR A CA  1 
ATOM   6668  C C   . TYR A 1 861 ? 17.855  27.117  10.967  1.00 166.46 ? 936  TYR A C   1 
ATOM   6669  O O   . TYR A 1 861 ? 18.781  26.464  10.475  1.00 155.51 ? 936  TYR A O   1 
ATOM   6670  C CB  . TYR A 1 861 ? 15.956  25.637  10.310  1.00 133.15 ? 936  TYR A CB  1 
ATOM   6671  C CG  . TYR A 1 861 ? 14.986  24.553  10.729  1.00 144.74 ? 936  TYR A CG  1 
ATOM   6672  C CD1 . TYR A 1 861 ? 15.444  23.321  11.183  1.00 157.63 ? 936  TYR A CD1 1 
ATOM   6673  C CD2 . TYR A 1 861 ? 13.616  24.754  10.655  1.00 149.79 ? 936  TYR A CD2 1 
ATOM   6674  C CE1 . TYR A 1 861 ? 14.560  22.324  11.557  1.00 169.41 ? 936  TYR A CE1 1 
ATOM   6675  C CE2 . TYR A 1 861 ? 12.725  23.765  11.027  1.00 154.08 ? 936  TYR A CE2 1 
ATOM   6676  C CZ  . TYR A 1 861 ? 13.201  22.553  11.477  1.00 161.82 ? 936  TYR A CZ  1 
ATOM   6677  O OH  . TYR A 1 861 ? 12.312  21.570  11.845  1.00 160.99 ? 936  TYR A OH  1 
ATOM   6678  N N   . ASN A 1 862 ? 17.897  28.442  11.083  1.00 174.10 ? 937  ASN A N   1 
ATOM   6679  C CA  . ASN A 1 862 ? 19.077  29.234  10.767  1.00 168.22 ? 937  ASN A CA  1 
ATOM   6680  C C   . ASN A 1 862 ? 20.119  29.216  11.877  1.00 173.57 ? 937  ASN A C   1 
ATOM   6681  O O   . ASN A 1 862 ? 21.067  30.007  11.823  1.00 181.91 ? 937  ASN A O   1 
ATOM   6682  C CB  . ASN A 1 862 ? 18.661  30.677  10.460  1.00 167.42 ? 937  ASN A CB  1 
ATOM   6683  C CG  . ASN A 1 862 ? 18.138  31.417  11.686  1.00 179.08 ? 937  ASN A CG  1 
ATOM   6684  O OD1 . ASN A 1 862 ? 16.937  31.651  11.812  1.00 182.35 ? 937  ASN A OD1 1 
ATOM   6685  N ND2 . ASN A 1 862 ? 19.042  31.823  12.574  1.00 178.08 ? 937  ASN A ND2 1 
ATOM   6686  N N   . PHE A 1 863 ? 19.963  28.355  12.884  1.00 171.75 ? 938  PHE A N   1 
ATOM   6687  C CA  . PHE A 1 863 ? 20.886  28.348  14.013  1.00 169.89 ? 938  PHE A CA  1 
ATOM   6688  C C   . PHE A 1 863 ? 22.292  27.992  13.545  1.00 169.47 ? 938  PHE A C   1 
ATOM   6689  O O   . PHE A 1 863 ? 22.488  27.031  12.798  1.00 170.61 ? 938  PHE A O   1 
ATOM   6690  C CB  . PHE A 1 863 ? 20.404  27.368  15.089  1.00 167.69 ? 938  PHE A CB  1 
ATOM   6691  C CG  . PHE A 1 863 ? 20.116  25.981  14.579  1.00 163.02 ? 938  PHE A CG  1 
ATOM   6692  C CD1 . PHE A 1 863 ? 21.127  25.036  14.484  1.00 157.60 ? 938  PHE A CD1 1 
ATOM   6693  C CD2 . PHE A 1 863 ? 18.828  25.616  14.218  1.00 161.03 ? 938  PHE A CD2 1 
ATOM   6694  C CE1 . PHE A 1 863 ? 20.867  23.762  14.019  1.00 147.64 ? 938  PHE A CE1 1 
ATOM   6695  C CE2 . PHE A 1 863 ? 18.556  24.340  13.754  1.00 160.95 ? 938  PHE A CE2 1 
ATOM   6696  C CZ  . PHE A 1 863 ? 19.579  23.411  13.654  1.00 156.29 ? 938  PHE A CZ  1 
ATOM   6697  N N   . ASP A 1 864 ? 23.269  28.788  13.966  1.00 166.01 ? 939  ASP A N   1 
ATOM   6698  C CA  . ASP A 1 864 ? 24.651  28.560  13.578  1.00 175.60 ? 939  ASP A CA  1 
ATOM   6699  C C   . ASP A 1 864 ? 25.259  27.439  14.411  1.00 182.10 ? 939  ASP A C   1 
ATOM   6700  O O   . ASP A 1 864 ? 24.826  27.167  15.533  1.00 187.00 ? 939  ASP A O   1 
ATOM   6701  C CB  . ASP A 1 864 ? 25.472  29.842  13.738  1.00 174.81 ? 939  ASP A CB  1 
ATOM   6702  C CG  . ASP A 1 864 ? 25.159  30.585  15.028  1.00 173.76 ? 939  ASP A CG  1 
ATOM   6703  O OD1 . ASP A 1 864 ? 23.979  30.933  15.248  1.00 165.95 ? 939  ASP A OD1 1 
ATOM   6704  O OD2 . ASP A 1 864 ? 26.096  30.821  15.821  1.00 176.54 ? 939  ASP A OD2 1 
ATOM   6705  N N   . ARG A 1 865 ? 26.272  26.775  13.846  1.00 182.91 ? 940  ARG A N   1 
ATOM   6706  C CA  . ARG A 1 865 ? 26.987  25.770  14.625  1.00 182.68 ? 940  ARG A CA  1 
ATOM   6707  C C   . ARG A 1 865 ? 27.663  26.392  15.836  1.00 187.79 ? 940  ARG A C   1 
ATOM   6708  O O   . ARG A 1 865 ? 27.790  25.741  16.880  1.00 220.07 ? 940  ARG A O   1 
ATOM   6709  C CB  . ARG A 1 865 ? 28.027  25.036  13.774  1.00 191.47 ? 940  ARG A CB  1 
ATOM   6710  C CG  . ARG A 1 865 ? 27.663  24.765  12.322  1.00 185.71 ? 940  ARG A CG  1 
ATOM   6711  C CD  . ARG A 1 865 ? 26.393  23.940  12.195  1.00 171.55 ? 940  ARG A CD  1 
ATOM   6712  N NE  . ARG A 1 865 ? 25.191  24.755  12.065  1.00 177.78 ? 940  ARG A NE  1 
ATOM   6713  C CZ  . ARG A 1 865 ? 23.960  24.354  12.354  1.00 185.12 ? 940  ARG A CZ  1 
ATOM   6714  N NH1 . ARG A 1 865 ? 23.739  23.222  12.993  1.00 211.22 ? 940  ARG A NH1 1 
ATOM   6715  N NH2 . ARG A 1 865 ? 22.928  25.107  11.986  1.00 180.69 ? 940  ARG A NH2 1 
ATOM   6716  N N   . SER A 1 866 ? 28.098  27.647  15.720  1.00 184.76 ? 941  SER A N   1 
ATOM   6717  C CA  . SER A 1 866 ? 28.774  28.301  16.832  1.00 180.29 ? 941  SER A CA  1 
ATOM   6718  C C   . SER A 1 866 ? 27.807  28.742  17.919  1.00 182.56 ? 941  SER A C   1 
ATOM   6719  O O   . SER A 1 866 ? 28.254  29.084  19.019  1.00 184.68 ? 941  SER A O   1 
ATOM   6720  C CB  . SER A 1 866 ? 29.562  29.502  16.321  1.00 167.89 ? 941  SER A CB  1 
ATOM   6721  O OG  . SER A 1 866 ? 28.740  30.313  15.503  1.00 171.85 ? 941  SER A OG  1 
ATOM   6722  N N   . SER A 1 867 ? 26.504  28.745  17.637  1.00 182.76 ? 942  SER A N   1 
ATOM   6723  C CA  . SER A 1 867 ? 25.515  29.147  18.628  1.00 176.75 ? 942  SER A CA  1 
ATOM   6724  C C   . SER A 1 867 ? 25.657  28.305  19.886  1.00 167.10 ? 942  SER A C   1 
ATOM   6725  O O   . SER A 1 867 ? 25.791  27.080  19.816  1.00 176.79 ? 942  SER A O   1 
ATOM   6726  C CB  . SER A 1 867 ? 24.105  29.010  18.052  1.00 174.82 ? 942  SER A CB  1 
ATOM   6727  O OG  . SER A 1 867 ? 23.694  27.654  18.032  1.00 184.54 ? 942  SER A OG  1 
ATOM   6728  N N   . SER A 1 868 ? 25.633  28.980  21.040  1.00 155.61 ? 943  SER A N   1 
ATOM   6729  C CA  . SER A 1 868 ? 25.912  28.315  22.308  1.00 150.16 ? 943  SER A CA  1 
ATOM   6730  C C   . SER A 1 868 ? 25.001  27.120  22.545  1.00 146.32 ? 943  SER A C   1 
ATOM   6731  O O   . SER A 1 868 ? 25.410  26.147  23.187  1.00 147.74 ? 943  SER A O   1 
ATOM   6732  C CB  . SER A 1 868 ? 25.781  29.316  23.458  1.00 141.49 ? 943  SER A CB  1 
ATOM   6733  O OG  . SER A 1 868 ? 24.441  29.752  23.601  1.00 142.76 ? 943  SER A OG  1 
ATOM   6734  N N   . THR A 1 869 ? 23.772  27.164  22.028  1.00 131.79 ? 944  THR A N   1 
ATOM   6735  C CA  . THR A 1 869 ? 22.853  26.045  22.207  1.00 123.74 ? 944  THR A CA  1 
ATOM   6736  C C   . THR A 1 869 ? 23.358  24.797  21.489  1.00 128.92 ? 944  THR A C   1 
ATOM   6737  O O   . THR A 1 869 ? 23.487  23.725  22.093  1.00 126.32 ? 944  THR A O   1 
ATOM   6738  C CB  . THR A 1 869 ? 21.460  26.430  21.706  1.00 124.83 ? 944  THR A CB  1 
ATOM   6739  O OG1 . THR A 1 869 ? 21.133  27.749  22.160  1.00 149.14 ? 944  THR A OG1 1 
ATOM   6740  C CG2 . THR A 1 869 ? 20.417  25.449  22.218  1.00 103.49 ? 944  THR A CG2 1 
ATOM   6741  N N   . PHE A 1 870 ? 23.645  24.920  20.191  1.00 137.64 ? 945  PHE A N   1 
ATOM   6742  C CA  . PHE A 1 870 ? 24.119  23.773  19.424  1.00 139.40 ? 945  PHE A CA  1 
ATOM   6743  C C   . PHE A 1 870 ? 25.484  23.307  19.918  1.00 134.66 ? 945  PHE A C   1 
ATOM   6744  O O   . PHE A 1 870 ? 25.752  22.100  19.982  1.00 130.74 ? 945  PHE A O   1 
ATOM   6745  C CB  . PHE A 1 870 ? 24.176  24.130  17.939  1.00 137.33 ? 945  PHE A CB  1 
ATOM   6746  C CG  . PHE A 1 870 ? 24.602  22.994  17.058  1.00 139.69 ? 945  PHE A CG  1 
ATOM   6747  C CD1 . PHE A 1 870 ? 23.691  22.029  16.669  1.00 135.13 ? 945  PHE A CD1 1 
ATOM   6748  C CD2 . PHE A 1 870 ? 25.912  22.888  16.621  1.00 153.34 ? 945  PHE A CD2 1 
ATOM   6749  C CE1 . PHE A 1 870 ? 24.073  20.980  15.857  1.00 134.44 ? 945  PHE A CE1 1 
ATOM   6750  C CE2 . PHE A 1 870 ? 26.302  21.838  15.810  1.00 150.01 ? 945  PHE A CE2 1 
ATOM   6751  C CZ  . PHE A 1 870 ? 25.381  20.884  15.428  1.00 136.17 ? 945  PHE A CZ  1 
ATOM   6752  N N   . SER A 1 871 ? 26.360  24.253  20.267  1.00 133.53 ? 946  SER A N   1 
ATOM   6753  C CA  . SER A 1 871 ? 27.657  23.889  20.826  1.00 138.40 ? 946  SER A CA  1 
ATOM   6754  C C   . SER A 1 871 ? 27.495  23.122  22.131  1.00 133.75 ? 946  SER A C   1 
ATOM   6755  O O   . SER A 1 871 ? 28.251  22.186  22.406  1.00 124.04 ? 946  SER A O   1 
ATOM   6756  C CB  . SER A 1 871 ? 28.507  25.139  21.045  1.00 145.34 ? 946  SER A CB  1 
ATOM   6757  O OG  . SER A 1 871 ? 28.305  26.079  20.005  1.00 158.07 ? 946  SER A OG  1 
ATOM   6758  N N   . GLY A 1 872 ? 26.506  23.496  22.944  1.00 125.42 ? 947  GLY A N   1 
ATOM   6759  C CA  . GLY A 1 872 ? 26.275  22.778  24.185  1.00 123.47 ? 947  GLY A CA  1 
ATOM   6760  C C   . GLY A 1 872 ? 25.702  21.395  23.952  1.00 125.50 ? 947  GLY A C   1 
ATOM   6761  O O   . GLY A 1 872 ? 26.024  20.450  24.675  1.00 128.62 ? 947  GLY A O   1 
ATOM   6762  N N   . ILE A 1 873 ? 24.839  21.256  22.944  1.00 123.07 ? 948  ILE A N   1 
ATOM   6763  C CA  . ILE A 1 873 ? 24.361  19.924  22.578  1.00 123.23 ? 948  ILE A CA  1 
ATOM   6764  C C   . ILE A 1 873 ? 25.525  19.049  22.127  1.00 122.31 ? 948  ILE A C   1 
ATOM   6765  O O   . ILE A 1 873 ? 25.610  17.868  22.486  1.00 120.97 ? 948  ILE A O   1 
ATOM   6766  C CB  . ILE A 1 873 ? 23.263  20.011  21.502  1.00 120.01 ? 948  ILE A CB  1 
ATOM   6767  C CG1 . ILE A 1 873 ? 22.147  20.955  21.943  1.00 111.23 ? 948  ILE A CG1 1 
ATOM   6768  C CG2 . ILE A 1 873 ? 22.692  18.636  21.229  1.00 113.49 ? 948  ILE A CG2 1 
ATOM   6769  C CD1 . ILE A 1 873 ? 21.221  21.368  20.822  1.00 112.09 ? 948  ILE A CD1 1 
ATOM   6770  N N   . LYS A 1 874 ? 26.456  19.620  21.358  1.00 126.59 ? 949  LYS A N   1 
ATOM   6771  C CA  . LYS A 1 874 ? 27.622  18.854  20.919  1.00 126.23 ? 949  LYS A CA  1 
ATOM   6772  C C   . LYS A 1 874 ? 28.530  18.510  22.099  1.00 118.85 ? 949  LYS A C   1 
ATOM   6773  O O   . LYS A 1 874 ? 29.130  17.429  22.141  1.00 104.74 ? 949  LYS A O   1 
ATOM   6774  C CB  . LYS A 1 874 ? 28.382  19.640  19.847  1.00 128.60 ? 949  LYS A CB  1 
ATOM   6775  C CG  . LYS A 1 874 ? 28.005  19.263  18.421  1.00 134.09 ? 949  LYS A CG  1 
ATOM   6776  C CD  . LYS A 1 874 ? 28.981  19.834  17.401  1.00 124.47 ? 949  LYS A CD  1 
ATOM   6777  C CE  . LYS A 1 874 ? 30.326  19.133  17.445  1.00 134.37 ? 949  LYS A CE  1 
ATOM   6778  N NZ  . LYS A 1 874 ? 31.409  19.991  16.885  1.00 150.67 ? 949  LYS A NZ  1 
ATOM   6779  N N   . GLU A 1 875 ? 28.630  19.418  23.071  1.00 118.81 ? 950  GLU A N   1 
ATOM   6780  C CA  . GLU A 1 875 ? 29.433  19.176  24.266  1.00 115.97 ? 950  GLU A CA  1 
ATOM   6781  C C   . GLU A 1 875 ? 28.845  18.041  25.097  1.00 116.20 ? 950  GLU A C   1 
ATOM   6782  O O   . GLU A 1 875 ? 29.569  17.152  25.566  1.00 118.08 ? 950  GLU A O   1 
ATOM   6783  C CB  . GLU A 1 875 ? 29.517  20.468  25.082  1.00 109.32 ? 950  GLU A CB  1 
ATOM   6784  C CG  . GLU A 1 875 ? 30.434  20.434  26.295  1.00 118.28 ? 950  GLU A CG  1 
ATOM   6785  C CD  . GLU A 1 875 ? 31.713  19.652  26.059  1.00 131.07 ? 950  GLU A CD  1 
ATOM   6786  O OE1 . GLU A 1 875 ? 32.497  20.041  25.169  1.00 133.57 ? 950  GLU A OE1 1 
ATOM   6787  O OE2 . GLU A 1 875 ? 31.946  18.658  26.777  1.00 138.31 ? 950  GLU A OE2 1 
ATOM   6788  N N   . LEU A 1 876 ? 27.525  18.065  25.292  1.00 109.87 ? 951  LEU A N   1 
ATOM   6789  C CA  . LEU A 1 876 ? 26.846  16.975  25.982  1.00 112.15 ? 951  LEU A CA  1 
ATOM   6790  C C   . LEU A 1 876 ? 26.996  15.668  25.215  1.00 105.50 ? 951  LEU A C   1 
ATOM   6791  O O   . LEU A 1 876 ? 27.105  14.594  25.817  1.00 99.07  ? 951  LEU A O   1 
ATOM   6792  C CB  . LEU A 1 876 ? 25.368  17.322  26.175  1.00 121.71 ? 951  LEU A CB  1 
ATOM   6793  C CG  . LEU A 1 876 ? 24.584  16.597  27.271  1.00 106.34 ? 951  LEU A CG  1 
ATOM   6794  C CD1 . LEU A 1 876 ? 25.401  16.497  28.551  1.00 111.99 ? 951  LEU A CD1 1 
ATOM   6795  C CD2 . LEU A 1 876 ? 23.261  17.302  27.527  1.00 99.26  ? 951  LEU A CD2 1 
ATOM   6796  N N   . ALA A 1 877 ? 27.005  15.741  23.880  1.00 111.51 ? 952  ALA A N   1 
ATOM   6797  C CA  . ALA A 1 877 ? 27.222  14.542  23.078  1.00 105.78 ? 952  ALA A CA  1 
ATOM   6798  C C   . ALA A 1 877 ? 28.623  13.985  23.292  1.00 101.62 ? 952  ALA A C   1 
ATOM   6799  O O   . ALA A 1 877 ? 28.810  12.767  23.347  1.00 95.13  ? 952  ALA A O   1 
ATOM   6800  C CB  . ALA A 1 877 ? 26.984  14.848  21.600  1.00 94.92  ? 952  ALA A CB  1 
ATOM   6801  N N   . ARG A 1 878 ? 29.618  14.864  23.414  1.00 98.42  ? 953  ARG A N   1 
ATOM   6802  C CA  . ARG A 1 878 ? 30.972  14.416  23.727  1.00 108.58 ? 953  ARG A CA  1 
ATOM   6803  C C   . ARG A 1 878 ? 31.018  13.747  25.096  1.00 109.17 ? 953  ARG A C   1 
ATOM   6804  O O   . ARG A 1 878 ? 31.618  12.673  25.259  1.00 111.24 ? 953  ARG A O   1 
ATOM   6805  C CB  . ARG A 1 878 ? 31.936  15.603  23.665  1.00 111.27 ? 953  ARG A CB  1 
ATOM   6806  C CG  . ARG A 1 878 ? 33.406  15.257  23.834  1.00 102.27 ? 953  ARG A CG  1 
ATOM   6807  C CD  . ARG A 1 878 ? 34.059  16.112  24.910  1.00 115.53 ? 953  ARG A CD  1 
ATOM   6808  N NE  . ARG A 1 878 ? 33.440  15.914  26.214  1.00 138.90 ? 953  ARG A NE  1 
ATOM   6809  C CZ  . ARG A 1 878 ? 33.912  16.412  27.349  1.00 139.21 ? 953  ARG A CZ  1 
ATOM   6810  N NH1 . ARG A 1 878 ? 34.988  17.182  27.372  1.00 114.19 ? 953  ARG A NH1 1 
ATOM   6811  N NH2 . ARG A 1 878 ? 33.293  16.125  28.490  1.00 166.28 ? 953  ARG A NH2 1 
ATOM   6812  N N   . ARG A 1 879 ? 30.378  14.370  26.090  1.00 109.95 ? 954  ARG A N   1 
ATOM   6813  C CA  . ARG A 1 879 ? 30.302  13.775  27.422  1.00 103.93 ? 954  ARG A CA  1 
ATOM   6814  C C   . ARG A 1 879 ? 29.694  12.378  27.360  1.00 99.05  ? 954  ARG A C   1 
ATOM   6815  O O   . ARG A 1 879 ? 30.221  11.428  27.952  1.00 92.34  ? 954  ARG A O   1 
ATOM   6816  C CB  . ARG A 1 879 ? 29.481  14.665  28.355  1.00 104.95 ? 954  ARG A CB  1 
ATOM   6817  C CG  . ARG A 1 879 ? 30.032  16.065  28.557  1.00 117.07 ? 954  ARG A CG  1 
ATOM   6818  C CD  . ARG A 1 879 ? 29.729  16.570  29.964  1.00 136.89 ? 954  ARG A CD  1 
ATOM   6819  N NE  . ARG A 1 879 ? 30.888  17.204  30.581  1.00 140.69 ? 954  ARG A NE  1 
ATOM   6820  C CZ  . ARG A 1 879 ? 31.388  18.375  30.209  1.00 145.29 ? 954  ARG A CZ  1 
ATOM   6821  N NH1 . ARG A 1 879 ? 30.806  19.112  29.276  1.00 142.99 ? 954  ARG A NH1 1 
ATOM   6822  N NH2 . ARG A 1 879 ? 32.492  18.827  30.798  1.00 154.34 ? 954  ARG A NH2 1 
ATOM   6823  N N   . PHE A 1 880 ? 28.573  12.240  26.647  1.00 104.53 ? 955  PHE A N   1 
ATOM   6824  C CA  . PHE A 1 880 ? 27.949  10.932  26.470  1.00 100.44 ? 955  PHE A CA  1 
ATOM   6825  C C   . PHE A 1 880 ? 28.891  9.966   25.764  1.00 99.84  ? 955  PHE A C   1 
ATOM   6826  O O   . PHE A 1 880 ? 28.940  8.776   26.098  1.00 98.25  ? 955  PHE A O   1 
ATOM   6827  C CB  . PHE A 1 880 ? 26.649  11.068  25.674  1.00 91.53  ? 955  PHE A CB  1 
ATOM   6828  C CG  . PHE A 1 880 ? 25.558  11.816  26.391  1.00 93.65  ? 955  PHE A CG  1 
ATOM   6829  C CD1 . PHE A 1 880 ? 25.634  12.055  27.751  1.00 106.51 ? 955  PHE A CD1 1 
ATOM   6830  C CD2 . PHE A 1 880 ? 24.456  12.286  25.695  1.00 106.98 ? 955  PHE A CD2 1 
ATOM   6831  C CE1 . PHE A 1 880 ? 24.629  12.745  28.405  1.00 110.15 ? 955  PHE A CE1 1 
ATOM   6832  C CE2 . PHE A 1 880 ? 23.450  12.977  26.343  1.00 101.74 ? 955  PHE A CE2 1 
ATOM   6833  C CZ  . PHE A 1 880 ? 23.536  13.206  27.700  1.00 95.04  ? 955  PHE A CZ  1 
ATOM   6834  N N   . ALA A 1 881 ? 29.641  10.464  24.779  1.00 90.88  ? 956  ALA A N   1 
ATOM   6835  C CA  . ALA A 1 881 ? 30.531  9.609   24.005  1.00 101.21 ? 956  ALA A CA  1 
ATOM   6836  C C   . ALA A 1 881 ? 31.620  9.012   24.879  1.00 103.65 ? 956  ALA A C   1 
ATOM   6837  O O   . ALA A 1 881 ? 32.001  7.848   24.699  1.00 105.60 ? 956  ALA A O   1 
ATOM   6838  C CB  . ALA A 1 881 ? 31.144  10.403  22.852  1.00 113.87 ? 956  ALA A CB  1 
ATOM   6839  N N   . LEU A 1 882 ? 32.137  9.793   25.832  1.00 104.90 ? 957  LEU A N   1 
ATOM   6840  C CA  . LEU A 1 882 ? 33.141  9.255   26.747  1.00 103.90 ? 957  LEU A CA  1 
ATOM   6841  C C   . LEU A 1 882 ? 32.628  8.009   27.462  1.00 104.72 ? 957  LEU A C   1 
ATOM   6842  O O   . LEU A 1 882 ? 33.370  7.038   27.646  1.00 102.64 ? 957  LEU A O   1 
ATOM   6843  C CB  . LEU A 1 882 ? 33.563  10.321  27.757  1.00 92.22  ? 957  LEU A CB  1 
ATOM   6844  C CG  . LEU A 1 882 ? 33.953  11.674  27.162  1.00 90.03  ? 957  LEU A CG  1 
ATOM   6845  C CD1 . LEU A 1 882 ? 34.418  12.620  28.251  1.00 102.65 ? 957  LEU A CD1 1 
ATOM   6846  C CD2 . LEU A 1 882 ? 35.028  11.510  26.099  1.00 106.28 ? 957  LEU A CD2 1 
ATOM   6847  N N   . THR A 1 883 ? 31.358  8.013   27.855  1.00 105.07 ? 958  THR A N   1 
ATOM   6848  C CA  . THR A 1 883 ? 30.743  6.855   28.494  1.00 95.25  ? 958  THR A CA  1 
ATOM   6849  C C   . THR A 1 883 ? 30.674  5.660   27.547  1.00 102.53 ? 958  THR A C   1 
ATOM   6850  O O   . THR A 1 883 ? 31.120  4.562   27.881  1.00 83.77  ? 958  THR A O   1 
ATOM   6851  C CB  . THR A 1 883 ? 29.327  7.179   28.987  1.00 96.19  ? 958  THR A CB  1 
ATOM   6852  O OG1 . THR A 1 883 ? 28.399  7.015   27.907  1.00 105.91 ? 958  THR A OG1 1 
ATOM   6853  C CG2 . THR A 1 883 ? 29.258  8.610   29.493  1.00 86.54  ? 958  THR A CG2 1 
ATOM   6854  N N   . ASP A 1 887 ? 36.487  0.353   24.188  1.00 163.16 ? 962  ASP A N   1 
ATOM   6855  C CA  . ASP A 1 887 ? 35.070  0.157   23.899  1.00 181.50 ? 962  ASP A CA  1 
ATOM   6856  C C   . ASP A 1 887 ? 34.849  -1.088  23.041  1.00 182.66 ? 962  ASP A C   1 
ATOM   6857  O O   . ASP A 1 887 ? 34.115  -1.054  22.053  1.00 185.87 ? 962  ASP A O   1 
ATOM   6858  C CB  . ASP A 1 887 ? 34.491  1.393   23.205  1.00 191.84 ? 962  ASP A CB  1 
ATOM   6859  C CG  . ASP A 1 887 ? 35.441  1.987   22.183  1.00 185.25 ? 962  ASP A CG  1 
ATOM   6860  O OD1 . ASP A 1 887 ? 35.982  1.224   21.356  1.00 178.32 ? 962  ASP A OD1 1 
ATOM   6861  O OD2 . ASP A 1 887 ? 35.657  3.217   22.216  1.00 178.53 ? 962  ASP A OD2 1 
ATOM   6862  N N   . GLN A 1 888 ? 35.495  -2.185  23.432  1.00 175.31 ? 963  GLN A N   1 
ATOM   6863  C CA  . GLN A 1 888 ? 35.387  -3.454  22.728  1.00 175.23 ? 963  GLN A CA  1 
ATOM   6864  C C   . GLN A 1 888 ? 34.471  -4.445  23.428  1.00 174.75 ? 963  GLN A C   1 
ATOM   6865  O O   . GLN A 1 888 ? 34.205  -5.516  22.876  1.00 166.72 ? 963  GLN A O   1 
ATOM   6866  C CB  . GLN A 1 888 ? 36.779  -4.084  22.564  1.00 186.03 ? 963  GLN A CB  1 
ATOM   6867  C CG  . GLN A 1 888 ? 37.864  -3.105  22.152  1.00 188.45 ? 963  GLN A CG  1 
ATOM   6868  C CD  . GLN A 1 888 ? 37.486  -2.304  20.926  1.00 185.60 ? 963  GLN A CD  1 
ATOM   6869  O OE1 . GLN A 1 888 ? 37.151  -2.866  19.887  1.00 190.22 ? 963  GLN A OE1 1 
ATOM   6870  N NE2 . GLN A 1 888 ? 37.527  -0.982  21.045  1.00 177.24 ? 963  GLN A NE2 1 
ATOM   6871  N N   . LEU A 1 889 ? 33.988  -4.111  24.624  1.00 179.40 ? 964  LEU A N   1 
ATOM   6872  C CA  . LEU A 1 889 ? 33.174  -5.015  25.434  1.00 176.16 ? 964  LEU A CA  1 
ATOM   6873  C C   . LEU A 1 889 ? 31.707  -4.786  25.080  1.00 181.73 ? 964  LEU A C   1 
ATOM   6874  O O   . LEU A 1 889 ? 30.948  -4.145  25.813  1.00 222.30 ? 964  LEU A O   1 
ATOM   6875  C CB  . LEU A 1 889 ? 33.446  -4.772  26.913  1.00 161.98 ? 964  LEU A CB  1 
ATOM   6876  C CG  . LEU A 1 889 ? 33.155  -5.834  27.974  1.00 160.37 ? 964  LEU A CG  1 
ATOM   6877  C CD1 . LEU A 1 889 ? 33.690  -5.355  29.317  1.00 167.31 ? 964  LEU A CD1 1 
ATOM   6878  C CD2 . LEU A 1 889 ? 31.678  -6.171  28.077  1.00 148.08 ? 964  LEU A CD2 1 
ATOM   6879  N N   . LYS A 1 890 ? 31.305  -5.333  23.927  1.00 186.88 ? 965  LYS A N   1 
ATOM   6880  C CA  . LYS A 1 890 ? 29.967  -5.161  23.356  1.00 177.00 ? 965  LYS A CA  1 
ATOM   6881  C C   . LYS A 1 890 ? 29.595  -3.691  23.156  1.00 160.83 ? 965  LYS A C   1 
ATOM   6882  O O   . LYS A 1 890 ? 28.548  -3.389  22.574  1.00 153.17 ? 965  LYS A O   1 
ATOM   6883  C CB  . LYS A 1 890 ? 28.897  -5.850  24.217  1.00 166.64 ? 965  LYS A CB  1 
ATOM   6884  C CG  . LYS A 1 890 ? 29.358  -7.038  25.071  1.00 159.29 ? 965  LYS A CG  1 
ATOM   6885  C CD  . LYS A 1 890 ? 29.979  -8.167  24.253  1.00 169.90 ? 965  LYS A CD  1 
ATOM   6886  C CE  . LYS A 1 890 ? 28.945  -8.882  23.395  1.00 166.30 ? 965  LYS A CE  1 
ATOM   6887  N NZ  . LYS A 1 890 ? 29.574  -9.871  22.473  1.00 169.22 ? 965  LYS A NZ  1 
ATOM   6888  N N   . THR A 1 891 ? 30.446  -2.778  23.631  1.00 164.34 ? 966  THR A N   1 
ATOM   6889  C CA  . THR A 1 891 ? 30.202  -1.348  23.484  1.00 153.69 ? 966  THR A CA  1 
ATOM   6890  C C   . THR A 1 891 ? 30.165  -0.937  22.015  1.00 154.39 ? 966  THR A C   1 
ATOM   6891  O O   . THR A 1 891 ? 29.417  -0.028  21.636  1.00 142.94 ? 966  THR A O   1 
ATOM   6892  C CB  . THR A 1 891 ? 31.291  -0.573  24.232  1.00 151.92 ? 966  THR A CB  1 
ATOM   6893  O OG1 . THR A 1 891 ? 31.447  -1.116  25.553  1.00 156.46 ? 966  THR A OG1 1 
ATOM   6894  C CG2 . THR A 1 891 ? 30.930  0.893   24.345  1.00 153.55 ? 966  THR A CG2 1 
ATOM   6895  N N   . ARG A 1 892 ? 30.969  -1.600  21.182  1.00 166.15 ? 967  ARG A N   1 
ATOM   6896  C CA  . ARG A 1 892 ? 30.962  -1.364  19.742  1.00 160.79 ? 967  ARG A CA  1 
ATOM   6897  C C   . ARG A 1 892 ? 29.592  -1.644  19.118  1.00 146.54 ? 967  ARG A C   1 
ATOM   6898  O O   . ARG A 1 892 ? 29.118  -0.868  18.278  1.00 135.44 ? 967  ARG A O   1 
ATOM   6899  C CB  . ARG A 1 892 ? 32.106  -2.185  19.129  1.00 159.22 ? 967  ARG A CB  1 
ATOM   6900  C CG  . ARG A 1 892 ? 32.232  -3.610  19.720  1.00 171.09 ? 967  ARG A CG  1 
ATOM   6901  C CD  . ARG A 1 892 ? 32.617  -4.736  18.758  1.00 165.11 ? 967  ARG A CD  1 
ATOM   6902  N NE  . ARG A 1 892 ? 31.602  -5.109  17.785  1.00 161.23 ? 967  ARG A NE  1 
ATOM   6903  C CZ  . ARG A 1 892 ? 31.882  -5.596  16.584  1.00 150.86 ? 967  ARG A CZ  1 
ATOM   6904  N NH1 . ARG A 1 892 ? 33.131  -5.742  16.173  1.00 141.38 ? 967  ARG A NH1 1 
ATOM   6905  N NH2 . ARG A 1 892 ? 30.886  -5.971  15.786  1.00 146.31 ? 967  ARG A NH2 1 
ATOM   6906  N N   . GLU A 1 893 ? 28.916  -2.704  19.562  1.00 147.03 ? 968  GLU A N   1 
ATOM   6907  C CA  . GLU A 1 893 ? 27.580  -3.016  19.062  1.00 140.95 ? 968  GLU A CA  1 
ATOM   6908  C C   . GLU A 1 893 ? 26.568  -1.929  19.445  1.00 130.07 ? 968  GLU A C   1 
ATOM   6909  O O   . GLU A 1 893 ? 25.823  -1.409  18.592  1.00 123.51 ? 968  GLU A O   1 
ATOM   6910  C CB  . GLU A 1 893 ? 27.174  -4.393  19.600  1.00 131.25 ? 968  GLU A CB  1 
ATOM   6911  C CG  . GLU A 1 893 ? 25.699  -4.645  19.800  1.00 124.11 ? 968  GLU A CG  1 
ATOM   6912  C CD  . GLU A 1 893 ? 25.439  -5.986  20.464  1.00 145.60 ? 968  GLU A CD  1 
ATOM   6913  O OE1 . GLU A 1 893 ? 26.300  -6.442  21.248  1.00 156.00 ? 968  GLU A OE1 1 
ATOM   6914  O OE2 . GLU A 1 893 ? 24.378  -6.588  20.196  1.00 151.36 ? 968  GLU A OE2 1 
ATOM   6915  N N   . ALA A 1 894 ? 26.539  -1.564  20.729  1.00 127.93 ? 969  ALA A N   1 
ATOM   6916  C CA  . ALA A 1 894 ? 25.652  -0.506  21.203  1.00 113.27 ? 969  ALA A CA  1 
ATOM   6917  C C   . ALA A 1 894 ? 25.892  0.807   20.460  1.00 109.89 ? 969  ALA A C   1 
ATOM   6918  O O   . ALA A 1 894 ? 24.939  1.505   20.085  1.00 104.22 ? 969  ALA A O   1 
ATOM   6919  C CB  . ALA A 1 894 ? 25.845  -0.315  22.706  1.00 117.67 ? 969  ALA A CB  1 
ATOM   6920  N N   . ILE A 1 895 ? 27.156  1.159   20.212  1.00 115.98 ? 970  ILE A N   1 
ATOM   6921  C CA  . ILE A 1 895 ? 27.401  2.428   19.529  1.00 117.78 ? 970  ILE A CA  1 
ATOM   6922  C C   . ILE A 1 895 ? 27.048  2.357   18.044  1.00 119.59 ? 970  ILE A C   1 
ATOM   6923  O O   . ILE A 1 895 ? 26.645  3.370   17.452  1.00 113.44 ? 970  ILE A O   1 
ATOM   6924  C CB  . ILE A 1 895 ? 28.849  2.906   19.750  1.00 102.94 ? 970  ILE A CB  1 
ATOM   6925  C CG1 . ILE A 1 895 ? 28.909  4.430   19.638  1.00 105.78 ? 970  ILE A CG1 1 
ATOM   6926  C CG2 . ILE A 1 895 ? 29.848  2.235   18.808  1.00 119.08 ? 970  ILE A CG2 1 
ATOM   6927  C CD1 . ILE A 1 895 ? 30.253  5.030   19.955  1.00 112.06 ? 970  ILE A CD1 1 
ATOM   6928  N N   . ALA A 1 896 ? 27.201  1.193   17.408  1.00 118.40 ? 971  ALA A N   1 
ATOM   6929  C CA  . ALA A 1 896 ? 26.654  1.029   16.064  1.00 112.90 ? 971  ALA A CA  1 
ATOM   6930  C C   . ALA A 1 896 ? 25.165  1.358   16.047  1.00 113.67 ? 971  ALA A C   1 
ATOM   6931  O O   . ALA A 1 896 ? 24.676  2.092   15.171  1.00 108.80 ? 971  ALA A O   1 
ATOM   6932  C CB  . ALA A 1 896 ? 26.902  -0.395  15.572  1.00 105.02 ? 971  ALA A CB  1 
ATOM   6933  N N   . MET A 1 897 ? 24.427  0.830   17.027  1.00 119.49 ? 972  MET A N   1 
ATOM   6934  C CA  . MET A 1 897 ? 22.998  1.130   17.089  1.00 115.99 ? 972  MET A CA  1 
ATOM   6935  C C   . MET A 1 897 ? 22.748  2.627   17.283  1.00 108.89 ? 972  MET A C   1 
ATOM   6936  O O   . MET A 1 897 ? 21.844  3.205   16.656  1.00 119.16 ? 972  MET A O   1 
ATOM   6937  C CB  . MET A 1 897 ? 22.333  0.322   18.201  1.00 97.79  ? 972  MET A CB  1 
ATOM   6938  C CG  . MET A 1 897 ? 20.843  0.571   18.294  1.00 107.52 ? 972  MET A CG  1 
ATOM   6939  S SD  . MET A 1 897 ? 19.894  -0.580  17.281  1.00 125.73 ? 972  MET A SD  1 
ATOM   6940  C CE  . MET A 1 897 ? 19.523  0.445   15.859  1.00 128.69 ? 972  MET A CE  1 
ATOM   6941  N N   . LEU A 1 898 ? 23.537  3.267   18.153  1.00 99.38  ? 973  LEU A N   1 
ATOM   6942  C CA  . LEU A 1 898 ? 23.398  4.708   18.369  1.00 98.47  ? 973  LEU A CA  1 
ATOM   6943  C C   . LEU A 1 898 ? 23.551  5.484   17.064  1.00 108.43 ? 973  LEU A C   1 
ATOM   6944  O O   . LEU A 1 898 ? 22.740  6.368   16.751  1.00 113.09 ? 973  LEU A O   1 
ATOM   6945  C CB  . LEU A 1 898 ? 24.419  5.185   19.407  1.00 104.02 ? 973  LEU A CB  1 
ATOM   6946  C CG  . LEU A 1 898 ? 24.579  6.695   19.624  1.00 114.40 ? 973  LEU A CG  1 
ATOM   6947  C CD1 . LEU A 1 898 ? 24.815  7.011   21.090  1.00 121.65 ? 973  LEU A CD1 1 
ATOM   6948  C CD2 . LEU A 1 898 ? 25.731  7.240   18.792  1.00 128.46 ? 973  LEU A CD2 1 
ATOM   6949  N N   . HIS A 1 899 ? 24.596  5.170   16.291  1.00 115.95 ? 974  HIS A N   1 
ATOM   6950  C CA  . HIS A 1 899 ? 24.819  5.870   15.026  1.00 109.79 ? 974  HIS A CA  1 
ATOM   6951  C C   . HIS A 1 899 ? 23.668  5.641   14.052  1.00 109.91 ? 974  HIS A C   1 
ATOM   6952  O O   . HIS A 1 899 ? 23.274  6.556   13.309  1.00 115.09 ? 974  HIS A O   1 
ATOM   6953  C CB  . HIS A 1 899 ? 26.144  5.426   14.405  1.00 111.90 ? 974  HIS A CB  1 
ATOM   6954  C CG  . HIS A 1 899 ? 27.321  6.239   14.846  1.00 113.69 ? 974  HIS A CG  1 
ATOM   6955  N ND1 . HIS A 1 899 ? 27.881  7.224   14.059  1.00 111.99 ? 974  HIS A ND1 1 
ATOM   6956  C CD2 . HIS A 1 899 ? 28.047  6.214   15.989  1.00 107.19 ? 974  HIS A CD2 1 
ATOM   6957  C CE1 . HIS A 1 899 ? 28.899  7.771   14.698  1.00 110.43 ? 974  HIS A CE1 1 
ATOM   6958  N NE2 . HIS A 1 899 ? 29.021  7.176   15.872  1.00 107.25 ? 974  HIS A NE2 1 
ATOM   6959  N N   . LYS A 1 900 ? 23.132  4.416   14.026  1.00 111.02 ? 975  LYS A N   1 
ATOM   6960  C CA  . LYS A 1 900 ? 21.985  4.133   13.166  1.00 115.43 ? 975  LYS A CA  1 
ATOM   6961  C C   . LYS A 1 900 ? 20.819  5.060   13.492  1.00 113.20 ? 975  LYS A C   1 
ATOM   6962  O O   . LYS A 1 900 ? 20.238  5.695   12.597  1.00 116.81 ? 975  LYS A O   1 
ATOM   6963  C CB  . LYS A 1 900 ? 21.568  2.671   13.318  1.00 115.12 ? 975  LYS A CB  1 
ATOM   6964  C CG  . LYS A 1 900 ? 20.647  2.165   12.219  1.00 134.70 ? 975  LYS A CG  1 
ATOM   6965  C CD  . LYS A 1 900 ? 21.058  2.699   10.856  1.00 139.42 ? 975  LYS A CD  1 
ATOM   6966  C CE  . LYS A 1 900 ? 20.182  2.125   9.758   1.00 125.57 ? 975  LYS A CE  1 
ATOM   6967  N NZ  . LYS A 1 900 ? 20.048  3.062   8.612   1.00 127.05 ? 975  LYS A NZ  1 
ATOM   6968  N N   . ASP A 1 901 ? 20.458  5.139   14.777  1.00 119.83 ? 976  ASP A N   1 
ATOM   6969  C CA  . ASP A 1 901 ? 19.371  6.033   15.179  1.00 120.25 ? 976  ASP A CA  1 
ATOM   6970  C C   . ASP A 1 901 ? 19.672  7.480   14.808  1.00 113.31 ? 976  ASP A C   1 
ATOM   6971  O O   . ASP A 1 901 ? 18.774  8.221   14.383  1.00 116.34 ? 976  ASP A O   1 
ATOM   6972  C CB  . ASP A 1 901 ? 19.102  5.917   16.679  1.00 120.02 ? 976  ASP A CB  1 
ATOM   6973  C CG  . ASP A 1 901 ? 18.562  4.561   17.072  1.00 128.00 ? 976  ASP A CG  1 
ATOM   6974  O OD1 . ASP A 1 901 ? 17.551  4.520   17.803  1.00 138.10 ? 976  ASP A OD1 1 
ATOM   6975  O OD2 . ASP A 1 901 ? 19.131  3.540   16.643  1.00 135.22 ? 976  ASP A OD2 1 
ATOM   6976  N N   . GLY A 1 902 ? 20.929  7.900   14.962  1.00 110.55 ? 977  GLY A N   1 
ATOM   6977  C CA  . GLY A 1 902 ? 21.278  9.274   14.634  1.00 114.19 ? 977  GLY A CA  1 
ATOM   6978  C C   . GLY A 1 902 ? 21.026  9.612   13.177  1.00 125.84 ? 977  GLY A C   1 
ATOM   6979  O O   . GLY A 1 902 ? 20.411  10.636  12.856  1.00 132.16 ? 977  GLY A O   1 
ATOM   6980  N N   . ILE A 1 903 ? 21.496  8.754   12.269  1.00 128.35 ? 978  ILE A N   1 
ATOM   6981  C CA  . ILE A 1 903 ? 21.317  9.053   10.849  1.00 116.06 ? 978  ILE A CA  1 
ATOM   6982  C C   . ILE A 1 903 ? 19.842  8.967   10.459  1.00 121.65 ? 978  ILE A C   1 
ATOM   6983  O O   . ILE A 1 903 ? 19.354  9.756   9.629   1.00 126.97 ? 978  ILE A O   1 
ATOM   6984  C CB  . ILE A 1 903 ? 22.201  8.139   9.979   1.00 116.18 ? 978  ILE A CB  1 
ATOM   6985  C CG1 . ILE A 1 903 ? 21.731  6.686   10.047  1.00 115.54 ? 978  ILE A CG1 1 
ATOM   6986  C CG2 . ILE A 1 903 ? 23.663  8.263   10.397  1.00 119.25 ? 978  ILE A CG2 1 
ATOM   6987  C CD1 . ILE A 1 903 ? 22.733  5.696   9.509   1.00 126.08 ? 978  ILE A CD1 1 
ATOM   6988  N N   . GLU A 1 904 ? 19.100  8.026   11.058  1.00 130.50 ? 979  GLU A N   1 
ATOM   6989  C CA  . GLU A 1 904 ? 17.673  7.950   10.759  1.00 122.83 ? 979  GLU A CA  1 
ATOM   6990  C C   . GLU A 1 904 ? 16.956  9.223   11.188  1.00 121.77 ? 979  GLU A C   1 
ATOM   6991  O O   . GLU A 1 904 ? 16.077  9.719   10.472  1.00 131.97 ? 979  GLU A O   1 
ATOM   6992  C CB  . GLU A 1 904 ? 17.045  6.728   11.425  1.00 114.55 ? 979  GLU A CB  1 
ATOM   6993  C CG  . GLU A 1 904 ? 17.436  5.410   10.792  1.00 121.71 ? 979  GLU A CG  1 
ATOM   6994  C CD  . GLU A 1 904 ? 17.289  4.252   11.750  1.00 128.25 ? 979  GLU A CD  1 
ATOM   6995  O OE1 . GLU A 1 904 ? 17.282  4.498   12.974  1.00 124.32 ? 979  GLU A OE1 1 
ATOM   6996  O OE2 . GLU A 1 904 ? 17.171  3.101   11.281  1.00 130.53 ? 979  GLU A OE2 1 
ATOM   6997  N N   . PHE A 1 905 ? 17.326  9.775   12.346  1.00 119.12 ? 980  PHE A N   1 
ATOM   6998  C CA  . PHE A 1 905 ? 16.744  11.045  12.767  1.00 121.13 ? 980  PHE A CA  1 
ATOM   6999  C C   . PHE A 1 905 ? 17.129  12.167  11.813  1.00 127.62 ? 980  PHE A C   1 
ATOM   7000  O O   . PHE A 1 905 ? 16.306  13.036  11.501  1.00 136.40 ? 980  PHE A O   1 
ATOM   7001  C CB  . PHE A 1 905 ? 17.183  11.385  14.192  1.00 113.22 ? 980  PHE A CB  1 
ATOM   7002  C CG  . PHE A 1 905 ? 16.823  12.782  14.626  1.00 126.29 ? 980  PHE A CG  1 
ATOM   7003  C CD1 . PHE A 1 905 ? 15.586  13.046  15.190  1.00 133.18 ? 980  PHE A CD1 1 
ATOM   7004  C CD2 . PHE A 1 905 ? 17.725  13.827  14.486  1.00 136.41 ? 980  PHE A CD2 1 
ATOM   7005  C CE1 . PHE A 1 905 ? 15.250  14.325  15.595  1.00 134.46 ? 980  PHE A CE1 1 
ATOM   7006  C CE2 . PHE A 1 905 ? 17.393  15.109  14.889  1.00 132.97 ? 980  PHE A CE2 1 
ATOM   7007  C CZ  . PHE A 1 905 ? 16.154  15.357  15.445  1.00 125.91 ? 980  PHE A CZ  1 
ATOM   7008  N N   . ALA A 1 906 ? 18.383  12.172  11.352  1.00 123.20 ? 981  ALA A N   1 
ATOM   7009  C CA  . ALA A 1 906 ? 18.826  13.226  10.445  1.00 123.64 ? 981  ALA A CA  1 
ATOM   7010  C C   . ALA A 1 906 ? 17.988  13.254  9.173   1.00 132.11 ? 981  ALA A C   1 
ATOM   7011  O O   . ALA A 1 906 ? 17.598  14.330  8.702   1.00 130.62 ? 981  ALA A O   1 
ATOM   7012  C CB  . ALA A 1 906 ? 20.306  13.047  10.108  1.00 114.63 ? 981  ALA A CB  1 
ATOM   7013  N N   . PHE A 1 907 ? 17.691  12.086  8.604   1.00 136.07 ? 982  PHE A N   1 
ATOM   7014  C CA  . PHE A 1 907 ? 16.910  12.033  7.371   1.00 136.20 ? 982  PHE A CA  1 
ATOM   7015  C C   . PHE A 1 907 ? 15.417  11.809  7.595   1.00 132.85 ? 982  PHE A C   1 
ATOM   7016  O O   . PHE A 1 907 ? 14.683  11.607  6.622   1.00 130.79 ? 982  PHE A O   1 
ATOM   7017  C CB  . PHE A 1 907 ? 17.461  10.965  6.430   1.00 136.62 ? 982  PHE A CB  1 
ATOM   7018  C CG  . PHE A 1 907 ? 18.817  11.289  5.880   1.00 140.79 ? 982  PHE A CG  1 
ATOM   7019  C CD1 . PHE A 1 907 ? 19.959  11.038  6.620   1.00 136.03 ? 982  PHE A CD1 1 
ATOM   7020  C CD2 . PHE A 1 907 ? 18.948  11.846  4.619   1.00 144.67 ? 982  PHE A CD2 1 
ATOM   7021  C CE1 . PHE A 1 907 ? 21.207  11.343  6.113   1.00 135.96 ? 982  PHE A CE1 1 
ATOM   7022  C CE2 . PHE A 1 907 ? 20.192  12.149  4.106   1.00 149.29 ? 982  PHE A CE2 1 
ATOM   7023  C CZ  . PHE A 1 907 ? 21.324  11.897  4.855   1.00 149.39 ? 982  PHE A CZ  1 
ATOM   7024  N N   . LYS A 1 908 ? 14.946  11.845  8.842   1.00 142.24 ? 983  LYS A N   1 
ATOM   7025  C CA  . LYS A 1 908 ? 13.514  11.688  9.086   1.00 126.76 ? 983  LYS A CA  1 
ATOM   7026  C C   . LYS A 1 908 ? 12.722  12.871  8.533   1.00 135.46 ? 983  LYS A C   1 
ATOM   7027  O O   . LYS A 1 908 ? 11.618  12.692  8.005   1.00 142.08 ? 983  LYS A O   1 
ATOM   7028  C CB  . LYS A 1 908 ? 13.264  11.498  10.585  1.00 134.71 ? 983  LYS A CB  1 
ATOM   7029  C CG  . LYS A 1 908 ? 11.823  11.685  11.048  1.00 144.94 ? 983  LYS A CG  1 
ATOM   7030  C CD  . LYS A 1 908 ? 11.589  13.079  11.622  1.00 152.90 ? 983  LYS A CD  1 
ATOM   7031  C CE  . LYS A 1 908 ? 12.318  13.267  12.943  1.00 158.68 ? 983  LYS A CE  1 
ATOM   7032  N NZ  . LYS A 1 908 ? 12.043  14.598  13.553  1.00 191.81 ? 983  LYS A NZ  1 
ATOM   7033  N N   . GLU A 1 909 ? 13.265  14.085  8.642   1.00 145.21 ? 984  GLU A N   1 
ATOM   7034  C CA  . GLU A 1 909 ? 12.614  15.264  8.088   1.00 150.22 ? 984  GLU A CA  1 
ATOM   7035  C C   . GLU A 1 909 ? 13.275  15.630  6.770   1.00 149.04 ? 984  GLU A C   1 
ATOM   7036  O O   . GLU A 1 909 ? 14.417  16.114  6.778   1.00 145.93 ? 984  GLU A O   1 
ATOM   7037  C CB  . GLU A 1 909 ? 12.693  16.436  9.065   1.00 158.76 ? 984  GLU A CB  1 
ATOM   7038  C CG  . GLU A 1 909 ? 11.695  16.374  10.208  1.00 157.85 ? 984  GLU A CG  1 
ATOM   7039  C CD  . GLU A 1 909 ? 12.107  17.232  11.389  1.00 169.35 ? 984  GLU A CD  1 
ATOM   7040  O OE1 . GLU A 1 909 ? 12.689  18.314  11.165  1.00 167.32 ? 984  GLU A OE1 1 
ATOM   7041  O OE2 . GLU A 1 909 ? 11.832  16.831  12.540  1.00 171.49 ? 984  GLU A OE2 1 
ATOM   7042  N N   . PRO A 1 910 ? 12.621  15.427  5.630   1.00 146.12 ? 985  PRO A N   1 
ATOM   7043  C CA  . PRO A 1 910 ? 13.243  15.772  4.352   1.00 141.39 ? 985  PRO A CA  1 
ATOM   7044  C C   . PRO A 1 910 ? 13.030  17.237  3.998   1.00 144.27 ? 985  PRO A C   1 
ATOM   7045  O O   . PRO A 1 910 ? 12.184  17.932  4.565   1.00 139.13 ? 985  PRO A O   1 
ATOM   7046  C CB  . PRO A 1 910 ? 12.527  14.848  3.365   1.00 121.74 ? 985  PRO A CB  1 
ATOM   7047  C CG  . PRO A 1 910 ? 11.145  14.776  3.917   1.00 108.46 ? 985  PRO A CG  1 
ATOM   7048  C CD  . PRO A 1 910 ? 11.296  14.808  5.435   1.00 136.68 ? 985  PRO A CD  1 
ATOM   7049  N N   . ASN A 1 911 ? 13.836  17.701  3.050   1.00 147.70 ? 986  ASN A N   1 
ATOM   7050  C CA  . ASN A 1 911 ? 13.776  19.096  2.625   1.00 148.74 ? 986  ASN A CA  1 
ATOM   7051  C C   . ASN A 1 911 ? 12.430  19.382  1.968   1.00 148.06 ? 986  ASN A C   1 
ATOM   7052  O O   . ASN A 1 911 ? 11.974  18.593  1.132   1.00 145.12 ? 986  ASN A O   1 
ATOM   7053  C CB  . ASN A 1 911 ? 14.918  19.406  1.661   1.00 157.05 ? 986  ASN A CB  1 
ATOM   7054  C CG  . ASN A 1 911 ? 14.943  20.861  1.231   1.00 165.14 ? 986  ASN A CG  1 
ATOM   7055  O OD1 . ASN A 1 911 ? 15.033  21.766  2.061   1.00 147.86 ? 986  ASN A OD1 1 
ATOM   7056  N ND2 . ASN A 1 911 ? 14.863  21.093  -0.075  1.00 197.65 ? 986  ASN A ND2 1 
ATOM   7057  N N   . PRO A 1 912 ? 11.765  20.488  2.316   1.00 152.37 ? 987  PRO A N   1 
ATOM   7058  C CA  . PRO A 1 912 ? 10.446  20.760  1.719   1.00 153.94 ? 987  PRO A CA  1 
ATOM   7059  C C   . PRO A 1 912 ? 10.495  21.004  0.220   1.00 154.22 ? 987  PRO A C   1 
ATOM   7060  O O   . PRO A 1 912 ? 9.634   20.499  -0.510  1.00 147.11 ? 987  PRO A O   1 
ATOM   7061  C CB  . PRO A 1 912 ? 9.967   22.001  2.488   1.00 148.65 ? 987  PRO A CB  1 
ATOM   7062  C CG  . PRO A 1 912 ? 11.222  22.635  3.008   1.00 148.51 ? 987  PRO A CG  1 
ATOM   7063  C CD  . PRO A 1 912 ? 12.128  21.488  3.333   1.00 148.83 ? 987  PRO A CD  1 
ATOM   7064  N N   . GLN A 1 913 ? 11.474  21.763  -0.263  1.00 156.74 ? 988  GLN A N   1 
ATOM   7065  C CA  . GLN A 1 913 ? 11.604  21.990  -1.700  1.00 146.08 ? 988  GLN A CA  1 
ATOM   7066  C C   . GLN A 1 913 ? 12.249  20.786  -2.380  1.00 145.66 ? 988  GLN A C   1 
ATOM   7067  O O   . GLN A 1 913 ? 13.041  20.068  -1.771  1.00 148.70 ? 988  GLN A O   1 
ATOM   7068  C CB  . GLN A 1 913 ? 12.418  23.254  -1.988  1.00 133.69 ? 988  GLN A CB  1 
ATOM   7069  C CG  . GLN A 1 913 ? 12.089  24.438  -1.095  1.00 142.24 ? 988  GLN A CG  1 
ATOM   7070  C CD  . GLN A 1 913 ? 13.312  25.268  -0.764  1.00 145.72 ? 988  GLN A CD  1 
ATOM   7071  O OE1 . GLN A 1 913 ? 14.444  24.795  -0.870  1.00 157.97 ? 988  GLN A OE1 1 
ATOM   7072  N NE2 . GLN A 1 913 ? 13.092  26.516  -0.369  1.00 156.13 ? 988  GLN A NE2 1 
ATOM   7073  N N   . PRO A 1 919 ? 17.748  17.543  3.727   1.00 121.25 ? 994  PRO A N   1 
ATOM   7074  C CA  . PRO A 1 919 ? 17.310  17.040  5.034   1.00 130.04 ? 994  PRO A CA  1 
ATOM   7075  C C   . PRO A 1 919 ? 17.351  18.116  6.115   1.00 130.69 ? 994  PRO A C   1 
ATOM   7076  O O   . PRO A 1 919 ? 18.350  18.826  6.242   1.00 144.03 ? 994  PRO A O   1 
ATOM   7077  C CB  . PRO A 1 919 ? 18.311  15.919  5.345   1.00 134.95 ? 994  PRO A CB  1 
ATOM   7078  C CG  . PRO A 1 919 ? 19.003  15.619  4.061   1.00 113.88 ? 994  PRO A CG  1 
ATOM   7079  C CD  . PRO A 1 919 ? 18.947  16.854  3.227   1.00 112.92 ? 994  PRO A CD  1 
ATOM   7080  N N   . LEU A 1 920 ? 16.274  18.219  6.897   1.00 124.87 ? 995  LEU A N   1 
ATOM   7081  C CA  . LEU A 1 920 ? 16.155  19.311  7.857   1.00 134.00 ? 995  LEU A CA  1 
ATOM   7082  C C   . LEU A 1 920 ? 17.117  19.138  9.027   1.00 142.35 ? 995  LEU A C   1 
ATOM   7083  O O   . LEU A 1 920 ? 17.688  20.119  9.516   1.00 140.22 ? 995  LEU A O   1 
ATOM   7084  C CB  . LEU A 1 920 ? 14.715  19.407  8.357   1.00 141.00 ? 995  LEU A CB  1 
ATOM   7085  C CG  . LEU A 1 920 ? 13.671  19.805  7.311   1.00 140.08 ? 995  LEU A CG  1 
ATOM   7086  C CD1 . LEU A 1 920 ? 12.331  20.102  7.967   1.00 155.12 ? 995  LEU A CD1 1 
ATOM   7087  C CD2 . LEU A 1 920 ? 14.148  20.994  6.491   1.00 143.72 ? 995  LEU A CD2 1 
ATOM   7088  N N   . ASN A 1 921 ? 17.307  17.904  9.491   1.00 140.77 ? 996  ASN A N   1 
ATOM   7089  C CA  . ASN A 1 921 ? 18.179  17.610  10.627  1.00 140.90 ? 996  ASN A CA  1 
ATOM   7090  C C   . ASN A 1 921 ? 19.565  17.170  10.183  1.00 144.32 ? 996  ASN A C   1 
ATOM   7091  O O   . ASN A 1 921 ? 20.191  16.318  10.819  1.00 138.65 ? 996  ASN A O   1 
ATOM   7092  C CB  . ASN A 1 921 ? 17.541  16.553  11.522  1.00 132.86 ? 996  ASN A CB  1 
ATOM   7093  C CG  . ASN A 1 921 ? 16.036  16.594  11.470  1.00 142.37 ? 996  ASN A CG  1 
ATOM   7094  O OD1 . ASN A 1 921 ? 15.392  15.670  10.977  1.00 145.03 ? 996  ASN A OD1 1 
ATOM   7095  N ND2 . ASN A 1 921 ? 15.461  17.677  11.981  1.00 162.10 ? 996  ASN A ND2 1 
ATOM   7096  N N   . LEU A 1 922 ? 20.063  17.743  9.085   1.00 152.49 ? 997  LEU A N   1 
ATOM   7097  C CA  . LEU A 1 922 ? 21.437  17.476  8.678   1.00 155.90 ? 997  LEU A CA  1 
ATOM   7098  C C   . LEU A 1 922 ? 22.413  17.892  9.770   1.00 150.43 ? 997  LEU A C   1 
ATOM   7099  O O   . LEU A 1 922 ? 23.416  17.207  10.010  1.00 142.91 ? 997  LEU A O   1 
ATOM   7100  C CB  . LEU A 1 922 ? 21.747  18.207  7.371   1.00 159.65 ? 997  LEU A CB  1 
ATOM   7101  C CG  . LEU A 1 922 ? 23.002  17.799  6.598   1.00 176.12 ? 997  LEU A CG  1 
ATOM   7102  C CD1 . LEU A 1 922 ? 22.716  16.585  5.730   1.00 175.94 ? 997  LEU A CD1 1 
ATOM   7103  C CD2 . LEU A 1 922 ? 23.514  18.960  5.757   1.00 196.74 ? 997  LEU A CD2 1 
ATOM   7104  N N   . ALA A 1 923 ? 22.116  19.005  10.458  1.00 148.32 ? 998  ALA A N   1 
ATOM   7105  C CA  . ALA A 1 923 ? 23.009  19.519  11.492  1.00 143.70 ? 998  ALA A CA  1 
ATOM   7106  C C   . ALA A 1 923 ? 23.290  18.461  12.549  1.00 131.95 ? 998  ALA A C   1 
ATOM   7107  O O   . ALA A 1 923 ? 24.411  18.371  13.065  1.00 134.76 ? 998  ALA A O   1 
ATOM   7108  C CB  . ALA A 1 923 ? 22.415  20.777  12.135  1.00 137.97 ? 998  ALA A CB  1 
ATOM   7109  N N   . PHE A 1 924 ? 22.292  17.625  12.855  1.00 123.09 ? 999  PHE A N   1 
ATOM   7110  C CA  . PHE A 1 924 ? 22.448  16.607  13.889  1.00 119.74 ? 999  PHE A CA  1 
ATOM   7111  C C   . PHE A 1 924 ? 23.625  15.680  13.619  1.00 123.48 ? 999  PHE A C   1 
ATOM   7112  O O   . PHE A 1 924 ? 24.137  15.059  14.559  1.00 121.66 ? 999  PHE A O   1 
ATOM   7113  C CB  . PHE A 1 924 ? 21.165  15.785  14.026  1.00 122.57 ? 999  PHE A CB  1 
ATOM   7114  C CG  . PHE A 1 924 ? 21.084  15.003  15.305  1.00 119.66 ? 999  PHE A CG  1 
ATOM   7115  C CD1 . PHE A 1 924 ? 20.919  15.656  16.515  1.00 116.69 ? 999  PHE A CD1 1 
ATOM   7116  C CD2 . PHE A 1 924 ? 21.164  13.619  15.300  1.00 108.46 ? 999  PHE A CD2 1 
ATOM   7117  C CE1 . PHE A 1 924 ? 20.844  14.947  17.700  1.00 110.27 ? 999  PHE A CE1 1 
ATOM   7118  C CE2 . PHE A 1 924 ? 21.086  12.903  16.480  1.00 108.33 ? 999  PHE A CE2 1 
ATOM   7119  C CZ  . PHE A 1 924 ? 20.927  13.567  17.681  1.00 111.18 ? 999  PHE A CZ  1 
ATOM   7120  N N   . LEU A 1 925 ? 24.069  15.582  12.362  1.00 130.26 ? 1000 LEU A N   1 
ATOM   7121  C CA  . LEU A 1 925 ? 25.229  14.755  12.051  1.00 134.91 ? 1000 LEU A CA  1 
ATOM   7122  C C   . LEU A 1 925 ? 26.443  15.180  12.865  1.00 130.66 ? 1000 LEU A C   1 
ATOM   7123  O O   . LEU A 1 925 ? 27.181  14.329  13.376  1.00 130.82 ? 1000 LEU A O   1 
ATOM   7124  C CB  . LEU A 1 925 ? 25.531  14.815  10.553  1.00 140.76 ? 1000 LEU A CB  1 
ATOM   7125  C CG  . LEU A 1 925 ? 24.606  13.975  9.668   1.00 149.14 ? 1000 LEU A CG  1 
ATOM   7126  C CD1 . LEU A 1 925 ? 25.241  13.692  8.317   1.00 168.38 ? 1000 LEU A CD1 1 
ATOM   7127  C CD2 . LEU A 1 925 ? 24.230  12.675  10.360  1.00 127.69 ? 1000 LEU A CD2 1 
ATOM   7128  N N   . ASP A 1 926 ? 26.654  16.494  13.014  1.00 126.62 ? 1001 ASP A N   1 
ATOM   7129  C CA  . ASP A 1 926 ? 27.732  16.976  13.874  1.00 124.37 ? 1001 ASP A CA  1 
ATOM   7130  C C   . ASP A 1 926 ? 27.625  16.369  15.264  1.00 123.73 ? 1001 ASP A C   1 
ATOM   7131  O O   . ASP A 1 926 ? 28.618  15.888  15.823  1.00 113.99 ? 1001 ASP A O   1 
ATOM   7132  C CB  . ASP A 1 926 ? 27.711  18.503  13.959  1.00 130.79 ? 1001 ASP A CB  1 
ATOM   7133  C CG  . ASP A 1 926 ? 27.831  19.163  12.605  1.00 130.33 ? 1001 ASP A CG  1 
ATOM   7134  O OD1 . ASP A 1 926 ? 28.684  18.721  11.807  1.00 137.30 ? 1001 ASP A OD1 1 
ATOM   7135  O OD2 . ASP A 1 926 ? 27.088  20.133  12.348  1.00 132.95 ? 1001 ASP A OD2 1 
ATOM   7136  N N   . ILE A 1 927 ? 26.414  16.369  15.830  1.00 124.07 ? 1002 ILE A N   1 
ATOM   7137  C CA  . ILE A 1 927 ? 26.196  15.716  17.118  1.00 116.87 ? 1002 ILE A CA  1 
ATOM   7138  C C   . ILE A 1 927 ? 26.687  14.278  17.056  1.00 112.03 ? 1002 ILE A C   1 
ATOM   7139  O O   . ILE A 1 927 ? 27.494  13.838  17.885  1.00 113.66 ? 1002 ILE A O   1 
ATOM   7140  C CB  . ILE A 1 927 ? 24.710  15.785  17.510  1.00 111.71 ? 1002 ILE A CB  1 
ATOM   7141  C CG1 . ILE A 1 927 ? 24.153  17.181  17.228  1.00 111.95 ? 1002 ILE A CG1 1 
ATOM   7142  C CG2 . ILE A 1 927 ? 24.532  15.423  18.978  1.00 105.48 ? 1002 ILE A CG2 1 
ATOM   7143  C CD1 . ILE A 1 927 ? 24.672  18.249  18.154  1.00 108.12 ? 1002 ILE A CD1 1 
ATOM   7144  N N   . LEU A 1 928 ? 26.236  13.538  16.039  1.00 106.36 ? 1003 LEU A N   1 
ATOM   7145  C CA  . LEU A 1 928 ? 26.659  12.151  15.883  1.00 105.51 ? 1003 LEU A CA  1 
ATOM   7146  C C   . LEU A 1 928 ? 28.166  12.049  15.685  1.00 117.67 ? 1003 LEU A C   1 
ATOM   7147  O O   . LEU A 1 928 ? 28.783  11.063  16.113  1.00 110.64 ? 1003 LEU A O   1 
ATOM   7148  C CB  . LEU A 1 928 ? 25.917  11.513  14.709  1.00 107.18 ? 1003 LEU A CB  1 
ATOM   7149  C CG  . LEU A 1 928 ? 25.767  9.992   14.736  1.00 107.15 ? 1003 LEU A CG  1 
ATOM   7150  C CD1 . LEU A 1 928 ? 25.217  9.541   16.076  1.00 97.37  ? 1003 LEU A CD1 1 
ATOM   7151  C CD2 . LEU A 1 928 ? 24.871  9.534   13.602  1.00 104.04 ? 1003 LEU A CD2 1 
ATOM   7152  N N   . SER A 1 929 ? 28.777  13.063  15.062  1.00 128.87 ? 1004 SER A N   1 
ATOM   7153  C CA  . SER A 1 929 ? 30.223  13.074  14.886  1.00 118.05 ? 1004 SER A CA  1 
ATOM   7154  C C   . SER A 1 929 ? 30.969  13.057  16.212  1.00 119.60 ? 1004 SER A C   1 
ATOM   7155  O O   . SER A 1 929 ? 32.134  12.650  16.247  1.00 128.41 ? 1004 SER A O   1 
ATOM   7156  C CB  . SER A 1 929 ? 30.636  14.303  14.072  1.00 118.41 ? 1004 SER A CB  1 
ATOM   7157  O OG  . SER A 1 929 ? 29.826  14.445  12.918  1.00 125.87 ? 1004 SER A OG  1 
ATOM   7158  N N   . GLU A 1 930 ? 30.326  13.484  17.301  1.00 117.95 ? 1005 GLU A N   1 
ATOM   7159  C CA  . GLU A 1 930 ? 30.973  13.409  18.605  1.00 104.65 ? 1005 GLU A CA  1 
ATOM   7160  C C   . GLU A 1 930 ? 31.227  11.966  19.017  1.00 96.18  ? 1005 GLU A C   1 
ATOM   7161  O O   . GLU A 1 930 ? 32.185  11.688  19.747  1.00 98.95  ? 1005 GLU A O   1 
ATOM   7162  C CB  . GLU A 1 930 ? 30.120  14.126  19.651  1.00 107.10 ? 1005 GLU A CB  1 
ATOM   7163  C CG  . GLU A 1 930 ? 29.901  15.593  19.333  1.00 110.96 ? 1005 GLU A CG  1 
ATOM   7164  C CD  . GLU A 1 930 ? 31.205  16.362  19.294  1.00 119.83 ? 1005 GLU A CD  1 
ATOM   7165  O OE1 . GLU A 1 930 ? 31.682  16.779  20.368  1.00 130.06 ? 1005 GLU A OE1 1 
ATOM   7166  O OE2 . GLU A 1 930 ? 31.761  16.540  18.188  1.00 136.08 ? 1005 GLU A OE2 1 
ATOM   7167  N N   . PHE A 1 931 ? 30.392  11.037  18.552  1.00 91.77  ? 1006 PHE A N   1 
ATOM   7168  C CA  . PHE A 1 931 ? 30.539  9.625   18.875  1.00 100.56 ? 1006 PHE A CA  1 
ATOM   7169  C C   . PHE A 1 931 ? 31.313  8.854   17.817  1.00 107.62 ? 1006 PHE A C   1 
ATOM   7170  O O   . PHE A 1 931 ? 31.574  7.662   18.013  1.00 113.28 ? 1006 PHE A O   1 
ATOM   7171  C CB  . PHE A 1 931 ? 29.161  8.975   19.066  1.00 108.91 ? 1006 PHE A CB  1 
ATOM   7172  C CG  . PHE A 1 931 ? 28.267  9.719   20.015  1.00 101.99 ? 1006 PHE A CG  1 
ATOM   7173  C CD1 . PHE A 1 931 ? 27.540  10.816  19.584  1.00 106.61 ? 1006 PHE A CD1 1 
ATOM   7174  C CD2 . PHE A 1 931 ? 28.149  9.321   21.335  1.00 88.75  ? 1006 PHE A CD2 1 
ATOM   7175  C CE1 . PHE A 1 931 ? 26.720  11.505  20.451  1.00 104.91 ? 1006 PHE A CE1 1 
ATOM   7176  C CE2 . PHE A 1 931 ? 27.328  10.009  22.208  1.00 91.06  ? 1006 PHE A CE2 1 
ATOM   7177  C CZ  . PHE A 1 931 ? 26.614  11.101  21.765  1.00 95.89  ? 1006 PHE A CZ  1 
ATOM   7178  N N   . SER A 1 932 ? 31.684  9.501   16.710  1.00 116.03 ? 1007 SER A N   1 
ATOM   7179  C CA  . SER A 1 932 ? 32.359  8.798   15.624  1.00 112.52 ? 1007 SER A CA  1 
ATOM   7180  C C   . SER A 1 932 ? 33.671  8.181   16.090  1.00 113.21 ? 1007 SER A C   1 
ATOM   7181  O O   . SER A 1 932 ? 34.061  7.105   15.620  1.00 116.53 ? 1007 SER A O   1 
ATOM   7182  C CB  . SER A 1 932 ? 32.601  9.753   14.455  1.00 114.74 ? 1007 SER A CB  1 
ATOM   7183  O OG  . SER A 1 932 ? 31.407  9.979   13.728  1.00 114.62 ? 1007 SER A OG  1 
ATOM   7184  N N   . SER A 1 933 ? 34.360  8.845   17.022  1.00 120.40 ? 1008 SER A N   1 
ATOM   7185  C CA  . SER A 1 933 ? 35.668  8.369   17.465  1.00 120.16 ? 1008 SER A CA  1 
ATOM   7186  C C   . SER A 1 933 ? 35.556  7.023   18.172  1.00 108.47 ? 1008 SER A C   1 
ATOM   7187  O O   . SER A 1 933 ? 36.389  6.134   17.961  1.00 120.17 ? 1008 SER A O   1 
ATOM   7188  C CB  . SER A 1 933 ? 36.316  9.406   18.383  1.00 115.16 ? 1008 SER A CB  1 
ATOM   7189  O OG  . SER A 1 933 ? 35.336  10.055  19.176  1.00 114.91 ? 1008 SER A OG  1 
ATOM   7190  N N   . LYS A 1 934 ? 34.521  6.846   19.001  1.00 114.54 ? 1009 LYS A N   1 
ATOM   7191  C CA  . LYS A 1 934 ? 34.336  5.582   19.705  1.00 118.14 ? 1009 LYS A CA  1 
ATOM   7192  C C   . LYS A 1 934 ? 33.991  4.446   18.755  1.00 113.60 ? 1009 LYS A C   1 
ATOM   7193  O O   . LYS A 1 934 ? 34.197  3.279   19.107  1.00 109.46 ? 1009 LYS A O   1 
ATOM   7194  C CB  . LYS A 1 934 ? 33.234  5.693   20.745  1.00 115.05 ? 1009 LYS A CB  1 
ATOM   7195  C CG  . LYS A 1 934 ? 33.120  7.026   21.453  1.00 100.42 ? 1009 LYS A CG  1 
ATOM   7196  C CD  . LYS A 1 934 ? 34.286  7.345   22.367  1.00 101.06 ? 1009 LYS A CD  1 
ATOM   7197  C CE  . LYS A 1 934 ? 34.469  8.857   22.444  1.00 105.74 ? 1009 LYS A CE  1 
ATOM   7198  N NZ  . LYS A 1 934 ? 35.087  9.292   23.716  1.00 101.76 ? 1009 LYS A NZ  1 
ATOM   7199  N N   . LEU A 1 935 ? 33.476  4.763   17.569  1.00 117.44 ? 1010 LEU A N   1 
ATOM   7200  C CA  . LEU A 1 935 ? 33.155  3.753   16.571  1.00 130.04 ? 1010 LEU A CA  1 
ATOM   7201  C C   . LEU A 1 935 ? 34.431  3.217   15.935  1.00 145.04 ? 1010 LEU A C   1 
ATOM   7202  O O   . LEU A 1 935 ? 35.329  3.987   15.579  1.00 156.58 ? 1010 LEU A O   1 
ATOM   7203  C CB  . LEU A 1 935 ? 32.233  4.351   15.507  1.00 120.69 ? 1010 LEU A CB  1 
ATOM   7204  C CG  . LEU A 1 935 ? 31.373  3.447   14.622  1.00 127.14 ? 1010 LEU A CG  1 
ATOM   7205  C CD1 . LEU A 1 935 ? 30.732  2.326   15.404  1.00 116.59 ? 1010 LEU A CD1 1 
ATOM   7206  C CD2 . LEU A 1 935 ? 30.308  4.286   13.955  1.00 132.15 ? 1010 LEU A CD2 1 
ATOM   7207  N N   . LEU A 1 936 ? 34.508  1.897   15.785  1.00 146.08 ? 1011 LEU A N   1 
ATOM   7208  C CA  . LEU A 1 936 ? 35.666  1.275   15.162  1.00 144.61 ? 1011 LEU A CA  1 
ATOM   7209  C C   . LEU A 1 936 ? 35.517  1.278   13.645  1.00 159.85 ? 1011 LEU A C   1 
ATOM   7210  O O   . LEU A 1 936 ? 34.406  1.320   13.109  1.00 168.77 ? 1011 LEU A O   1 
ATOM   7211  C CB  . LEU A 1 936 ? 35.853  -0.157  15.668  1.00 134.48 ? 1011 LEU A CB  1 
ATOM   7212  C CG  . LEU A 1 936 ? 35.569  -0.400  17.151  1.00 148.13 ? 1011 LEU A CG  1 
ATOM   7213  C CD1 . LEU A 1 936 ? 35.627  -1.880  17.492  1.00 148.39 ? 1011 LEU A CD1 1 
ATOM   7214  C CD2 . LEU A 1 936 ? 36.552  0.385   18.009  1.00 167.60 ? 1011 LEU A CD2 1 
ATOM   7215  N N   . ARG A 1 937 ? 36.658  1.229   12.953  1.00 155.55 ? 1012 ARG A N   1 
ATOM   7216  C CA  . ARG A 1 937 ? 36.640  1.305   11.496  1.00 160.87 ? 1012 ARG A CA  1 
ATOM   7217  C C   . ARG A 1 937 ? 35.793  0.187   10.894  1.00 157.69 ? 1012 ARG A C   1 
ATOM   7218  O O   . ARG A 1 937 ? 35.012  0.418   9.959   1.00 165.99 ? 1012 ARG A O   1 
ATOM   7219  C CB  . ARG A 1 937 ? 38.073  1.255   10.959  1.00 165.38 ? 1012 ARG A CB  1 
ATOM   7220  C CG  . ARG A 1 937 ? 38.303  2.097   9.727   1.00 176.38 ? 1012 ARG A CG  1 
ATOM   7221  C CD  . ARG A 1 937 ? 38.536  3.546   10.107  1.00 189.46 ? 1012 ARG A CD  1 
ATOM   7222  N NE  . ARG A 1 937 ? 38.484  4.415   8.939   1.00 202.86 ? 1012 ARG A NE  1 
ATOM   7223  C CZ  . ARG A 1 937 ? 38.298  5.727   8.980   1.00 189.30 ? 1012 ARG A CZ  1 
ATOM   7224  N NH1 . ARG A 1 937 ? 38.188  6.375   10.128  1.00 174.03 ? 1012 ARG A NH1 1 
ATOM   7225  N NH2 . ARG A 1 937 ? 38.220  6.407   7.840   1.00 196.81 ? 1012 ARG A NH2 1 
ATOM   7226  N N   . GLN A 1 938 ? 35.914  -1.026  11.441  1.00 148.33 ? 1013 GLN A N   1 
ATOM   7227  C CA  . GLN A 1 938 ? 35.153  -2.164  10.934  1.00 145.70 ? 1013 GLN A CA  1 
ATOM   7228  C C   . GLN A 1 938 ? 33.651  -1.917  11.043  1.00 153.35 ? 1013 GLN A C   1 
ATOM   7229  O O   . GLN A 1 938 ? 32.896  -2.175  10.098  1.00 150.40 ? 1013 GLN A O   1 
ATOM   7230  C CB  . GLN A 1 938 ? 35.552  -3.436  11.688  1.00 126.85 ? 1013 GLN A CB  1 
ATOM   7231  C CG  . GLN A 1 938 ? 35.787  -3.233  13.181  1.00 140.09 ? 1013 GLN A CG  1 
ATOM   7232  C CD  . GLN A 1 938 ? 37.235  -2.938  13.513  1.00 149.06 ? 1013 GLN A CD  1 
ATOM   7233  O OE1 . GLN A 1 938 ? 37.956  -2.336  12.718  1.00 146.80 ? 1013 GLN A OE1 1 
ATOM   7234  N NE2 . GLN A 1 938 ? 37.668  -3.355  14.697  1.00 165.18 ? 1013 GLN A NE2 1 
ATOM   7235  N N   . ASP A 1 939 ? 33.200  -1.415  12.196  1.00 154.17 ? 1014 ASP A N   1 
ATOM   7236  C CA  . ASP A 1 939 ? 31.793  -1.061  12.363  1.00 132.54 ? 1014 ASP A CA  1 
ATOM   7237  C C   . ASP A 1 939 ? 31.449  0.208   11.597  1.00 141.71 ? 1014 ASP A C   1 
ATOM   7238  O O   . ASP A 1 939 ? 30.301  0.383   11.143  1.00 157.69 ? 1014 ASP A O   1 
ATOM   7239  C CB  . ASP A 1 939 ? 31.485  -0.874  13.847  1.00 128.45 ? 1014 ASP A CB  1 
ATOM   7240  C CG  . ASP A 1 939 ? 31.731  -2.131  14.658  1.00 131.18 ? 1014 ASP A CG  1 
ATOM   7241  O OD1 . ASP A 1 939 ? 32.317  -3.092  14.115  1.00 138.07 ? 1014 ASP A OD1 1 
ATOM   7242  O OD2 . ASP A 1 939 ? 31.357  -2.149  15.851  1.00 133.90 ? 1014 ASP A OD2 1 
ATOM   7243  N N   . LYS A 1 940 ? 32.428  1.108   11.472  1.00 135.00 ? 1015 LYS A N   1 
ATOM   7244  C CA  . LYS A 1 940 ? 32.243  2.314   10.680  1.00 143.12 ? 1015 LYS A CA  1 
ATOM   7245  C C   . LYS A 1 940 ? 31.842  1.982   9.254   1.00 160.54 ? 1015 LYS A C   1 
ATOM   7246  O O   . LYS A 1 940 ? 31.063  2.720   8.651   1.00 165.01 ? 1015 LYS A O   1 
ATOM   7247  C CB  . LYS A 1 940 ? 33.523  3.154   10.679  1.00 139.20 ? 1015 LYS A CB  1 
ATOM   7248  C CG  . LYS A 1 940 ? 33.680  4.100   11.857  1.00 144.03 ? 1015 LYS A CG  1 
ATOM   7249  C CD  . LYS A 1 940 ? 34.629  5.242   11.506  1.00 144.11 ? 1015 LYS A CD  1 
ATOM   7250  C CE  . LYS A 1 940 ? 35.403  5.730   12.720  1.00 144.18 ? 1015 LYS A CE  1 
ATOM   7251  N NZ  . LYS A 1 940 ? 36.453  4.761   13.127  1.00 155.02 ? 1015 LYS A NZ  1 
ATOM   7252  N N   . ARG A 1 941 ? 32.354  0.879   8.698   1.00 161.72 ? 1016 ARG A N   1 
ATOM   7253  C CA  . ARG A 1 941 ? 31.970  0.508   7.336   1.00 162.56 ? 1016 ARG A CA  1 
ATOM   7254  C C   . ARG A 1 941 ? 30.473  0.233   7.225   1.00 161.20 ? 1016 ARG A C   1 
ATOM   7255  O O   . ARG A 1 941 ? 29.823  0.688   6.278   1.00 173.57 ? 1016 ARG A O   1 
ATOM   7256  C CB  . ARG A 1 941 ? 32.785  -0.697  6.861   1.00 157.48 ? 1016 ARG A CB  1 
ATOM   7257  C CG  . ARG A 1 941 ? 34.298  -0.617  7.131   1.00 163.50 ? 1016 ARG A CG  1 
ATOM   7258  C CD  . ARG A 1 941 ? 35.073  0.426   6.302   1.00 169.88 ? 1016 ARG A CD  1 
ATOM   7259  N NE  . ARG A 1 941 ? 34.489  1.763   6.331   1.00 173.19 ? 1016 ARG A NE  1 
ATOM   7260  C CZ  . ARG A 1 941 ? 34.796  2.703   7.215   1.00 176.50 ? 1016 ARG A CZ  1 
ATOM   7261  N NH1 . ARG A 1 941 ? 35.697  2.497   8.158   1.00 182.52 ? 1016 ARG A NH1 1 
ATOM   7262  N NH2 . ARG A 1 941 ? 34.173  3.876   7.157   1.00 175.60 ? 1016 ARG A NH2 1 
ATOM   7263  N N   . THR A 1 942 ? 29.900  -0.486  8.192   1.00 149.12 ? 1017 THR A N   1 
ATOM   7264  C CA  . THR A 1 942 ? 28.471  -0.789  8.133   1.00 154.10 ? 1017 THR A CA  1 
ATOM   7265  C C   . THR A 1 942 ? 27.632  0.468   8.341   1.00 155.22 ? 1017 THR A C   1 
ATOM   7266  O O   . THR A 1 942 ? 26.674  0.730   7.593   1.00 161.92 ? 1017 THR A O   1 
ATOM   7267  C CB  . THR A 1 942 ? 28.117  -1.845  9.179   1.00 135.83 ? 1017 THR A CB  1 
ATOM   7268  O OG1 . THR A 1 942 ? 28.623  -1.438  10.455  1.00 141.16 ? 1017 THR A OG1 1 
ATOM   7269  C CG2 . THR A 1 942 ? 28.735  -3.183  8.806   1.00 110.54 ? 1017 THR A CG2 1 
ATOM   7270  N N   . VAL A 1 943 ? 27.968  1.257   9.365   1.00 139.93 ? 1018 VAL A N   1 
ATOM   7271  C CA  . VAL A 1 943 ? 27.172  2.462   9.584   1.00 146.49 ? 1018 VAL A CA  1 
ATOM   7272  C C   . VAL A 1 943 ? 27.339  3.421   8.409   1.00 156.79 ? 1018 VAL A C   1 
ATOM   7273  O O   . VAL A 1 943 ? 26.416  4.171   8.067   1.00 170.45 ? 1018 VAL A O   1 
ATOM   7274  C CB  . VAL A 1 943 ? 27.522  3.126   10.929  1.00 130.59 ? 1018 VAL A CB  1 
ATOM   7275  C CG1 . VAL A 1 943 ? 27.369  2.129   12.076  1.00 129.72 ? 1018 VAL A CG1 1 
ATOM   7276  C CG2 . VAL A 1 943 ? 28.916  3.689   10.890  1.00 133.16 ? 1018 VAL A CG2 1 
ATOM   7277  N N   . TYR A 1 944 ? 28.484  3.367   7.729   1.00 153.62 ? 1019 TYR A N   1 
ATOM   7278  C CA  . TYR A 1 944 ? 28.706  4.201   6.560   1.00 162.92 ? 1019 TYR A CA  1 
ATOM   7279  C C   . TYR A 1 944 ? 27.916  3.698   5.366   1.00 172.85 ? 1019 TYR A C   1 
ATOM   7280  O O   . TYR A 1 944 ? 27.526  4.488   4.504   1.00 231.30 ? 1019 TYR A O   1 
ATOM   7281  C CB  . TYR A 1 944 ? 30.194  4.219   6.239   1.00 163.92 ? 1019 TYR A CB  1 
ATOM   7282  C CG  . TYR A 1 944 ? 30.651  5.411   5.460   1.00 168.79 ? 1019 TYR A CG  1 
ATOM   7283  C CD1 . TYR A 1 944 ? 30.334  6.697   5.863   1.00 178.43 ? 1019 TYR A CD1 1 
ATOM   7284  C CD2 . TYR A 1 944 ? 31.396  5.248   4.311   1.00 186.63 ? 1019 TYR A CD2 1 
ATOM   7285  C CE1 . TYR A 1 944 ? 30.758  7.787   5.138   1.00 167.02 ? 1019 TYR A CE1 1 
ATOM   7286  C CE2 . TYR A 1 944 ? 31.807  6.319   3.588   1.00 195.92 ? 1019 TYR A CE2 1 
ATOM   7287  C CZ  . TYR A 1 944 ? 31.501  7.588   3.996   1.00 169.58 ? 1019 TYR A CZ  1 
ATOM   7288  O OH  . TYR A 1 944 ? 31.949  8.640   3.233   1.00 159.72 ? 1019 TYR A OH  1 
ATOM   7289  N N   . VAL A 1 945 ? 27.695  2.385   5.290   1.00 164.36 ? 1020 VAL A N   1 
ATOM   7290  C CA  . VAL A 1 945 ? 26.787  1.831   4.289   1.00 162.14 ? 1020 VAL A CA  1 
ATOM   7291  C C   . VAL A 1 945 ? 25.381  2.376   4.503   1.00 166.79 ? 1020 VAL A C   1 
ATOM   7292  O O   . VAL A 1 945 ? 24.696  2.792   3.559   1.00 166.87 ? 1020 VAL A O   1 
ATOM   7293  C CB  . VAL A 1 945 ? 26.809  0.293   4.343   1.00 151.50 ? 1020 VAL A CB  1 
ATOM   7294  C CG1 . VAL A 1 945 ? 25.528  -0.282  3.760   1.00 156.36 ? 1020 VAL A CG1 1 
ATOM   7295  C CG2 . VAL A 1 945 ? 28.031  -0.243  3.618   1.00 154.48 ? 1020 VAL A CG2 1 
ATOM   7296  N N   . TYR A 1 946 ? 24.929  2.385   5.754   1.00 163.99 ? 1021 TYR A N   1 
ATOM   7297  C CA  . TYR A 1 946 ? 23.606  2.944   6.029   1.00 157.14 ? 1021 TYR A CA  1 
ATOM   7298  C C   . TYR A 1 946 ? 23.554  4.430   5.675   1.00 154.11 ? 1021 TYR A C   1 
ATOM   7299  O O   . TYR A 1 946 ? 22.576  4.911   5.084   1.00 162.26 ? 1021 TYR A O   1 
ATOM   7300  C CB  . TYR A 1 946 ? 23.230  2.717   7.491   1.00 154.38 ? 1021 TYR A CB  1 
ATOM   7301  C CG  . TYR A 1 946 ? 23.470  1.303   7.960   1.00 174.47 ? 1021 TYR A CG  1 
ATOM   7302  C CD1 . TYR A 1 946 ? 23.293  0.223   7.102   1.00 185.09 ? 1021 TYR A CD1 1 
ATOM   7303  C CD2 . TYR A 1 946 ? 23.881  1.046   9.259   1.00 194.24 ? 1021 TYR A CD2 1 
ATOM   7304  C CE1 . TYR A 1 946 ? 23.518  -1.068  7.526   1.00 198.27 ? 1021 TYR A CE1 1 
ATOM   7305  C CE2 . TYR A 1 946 ? 24.106  -0.241  9.692   1.00 201.53 ? 1021 TYR A CE2 1 
ATOM   7306  C CZ  . TYR A 1 946 ? 23.924  -1.293  8.824   1.00 201.01 ? 1021 TYR A CZ  1 
ATOM   7307  O OH  . TYR A 1 946 ? 24.150  -2.576  9.260   1.00 190.97 ? 1021 TYR A OH  1 
ATOM   7308  N N   . LEU A 1 947 ? 24.620  5.166   5.994   1.00 149.67 ? 1022 LEU A N   1 
ATOM   7309  C CA  . LEU A 1 947 ? 24.652  6.600   5.724   1.00 139.73 ? 1022 LEU A CA  1 
ATOM   7310  C C   . LEU A 1 947 ? 24.650  6.880   4.220   1.00 158.55 ? 1022 LEU A C   1 
ATOM   7311  O O   . LEU A 1 947 ? 23.940  7.781   3.744   1.00 161.28 ? 1022 LEU A O   1 
ATOM   7312  C CB  . LEU A 1 947 ? 25.886  7.202   6.400   1.00 139.02 ? 1022 LEU A CB  1 
ATOM   7313  C CG  . LEU A 1 947 ? 26.259  8.667   6.181   1.00 137.49 ? 1022 LEU A CG  1 
ATOM   7314  C CD1 . LEU A 1 947 ? 25.243  9.587   6.838   1.00 139.67 ? 1022 LEU A CD1 1 
ATOM   7315  C CD2 . LEU A 1 947 ? 27.674  8.973   6.657   1.00 143.80 ? 1022 LEU A CD2 1 
ATOM   7316  N N   . GLU A 1 948 ? 25.434  6.108   3.457   1.00 177.36 ? 1023 GLU A N   1 
ATOM   7317  C CA  . GLU A 1 948 ? 25.461  6.261   2.006   1.00 178.95 ? 1023 GLU A CA  1 
ATOM   7318  C C   . GLU A 1 948 ? 24.112  5.914   1.398   1.00 166.30 ? 1023 GLU A C   1 
ATOM   7319  O O   . GLU A 1 948 ? 23.688  6.537   0.416   1.00 164.26 ? 1023 GLU A O   1 
ATOM   7320  C CB  . GLU A 1 948 ? 26.561  5.394   1.386   1.00 187.29 ? 1023 GLU A CB  1 
ATOM   7321  C CG  . GLU A 1 948 ? 26.228  3.912   1.352   1.00 181.68 ? 1023 GLU A CG  1 
ATOM   7322  C CD  . GLU A 1 948 ? 27.177  3.094   0.520   1.00 175.01 ? 1023 GLU A CD  1 
ATOM   7323  O OE1 . GLU A 1 948 ? 27.040  1.852   0.504   1.00 190.97 ? 1023 GLU A OE1 1 
ATOM   7324  O OE2 . GLU A 1 948 ? 28.037  3.699   -0.141  1.00 148.34 ? 1023 GLU A OE2 1 
ATOM   7325  N N   . LYS A 1 949 ? 23.421  4.923   1.965   1.00 164.76 ? 1024 LYS A N   1 
ATOM   7326  C CA  . LYS A 1 949 ? 22.070  4.643   1.501   1.00 156.90 ? 1024 LYS A CA  1 
ATOM   7327  C C   . LYS A 1 949 ? 21.149  5.818   1.791   1.00 151.71 ? 1024 LYS A C   1 
ATOM   7328  O O   . LYS A 1 949 ? 20.218  6.081   1.022   1.00 151.88 ? 1024 LYS A O   1 
ATOM   7329  C CB  . LYS A 1 949 ? 21.563  3.341   2.136   1.00 133.48 ? 1024 LYS A CB  1 
ATOM   7330  C CG  . LYS A 1 949 ? 20.059  3.239   2.405   1.00 104.10 ? 1024 LYS A CG  1 
ATOM   7331  C CD  . LYS A 1 949 ? 19.624  3.858   3.735   1.00 119.81 ? 1024 LYS A CD  1 
ATOM   7332  C CE  . LYS A 1 949 ? 18.119  3.759   3.898   1.00 136.88 ? 1024 LYS A CE  1 
ATOM   7333  N NZ  . LYS A 1 949 ? 17.632  4.364   5.161   1.00 121.70 ? 1024 LYS A NZ  1 
ATOM   7334  N N   . PHE A 1 950 ? 21.399  6.541   2.882   1.00 156.94 ? 1025 PHE A N   1 
ATOM   7335  C CA  . PHE A 1 950 ? 20.577  7.716   3.161   1.00 149.12 ? 1025 PHE A CA  1 
ATOM   7336  C C   . PHE A 1 950 ? 20.830  8.857   2.172   1.00 150.48 ? 1025 PHE A C   1 
ATOM   7337  O O   . PHE A 1 950 ? 19.868  9.475   1.699   1.00 139.33 ? 1025 PHE A O   1 
ATOM   7338  C CB  . PHE A 1 950 ? 20.766  8.192   4.600   1.00 151.24 ? 1025 PHE A CB  1 
ATOM   7339  C CG  . PHE A 1 950 ? 19.769  7.605   5.565   1.00 138.37 ? 1025 PHE A CG  1 
ATOM   7340  C CD1 . PHE A 1 950 ? 18.418  7.906   5.447   1.00 123.55 ? 1025 PHE A CD1 1 
ATOM   7341  C CD2 . PHE A 1 950 ? 20.174  6.771   6.591   1.00 142.97 ? 1025 PHE A CD2 1 
ATOM   7342  C CE1 . PHE A 1 950 ? 17.495  7.378   6.329   1.00 124.88 ? 1025 PHE A CE1 1 
ATOM   7343  C CE2 . PHE A 1 950 ? 19.254  6.237   7.478   1.00 137.36 ? 1025 PHE A CE2 1 
ATOM   7344  C CZ  . PHE A 1 950 ? 17.911  6.545   7.346   1.00 133.49 ? 1025 PHE A CZ  1 
ATOM   7345  N N   . MET A 1 951 ? 22.088  9.184   1.844   1.00 158.05 ? 1026 MET A N   1 
ATOM   7346  C CA  . MET A 1 951 ? 22.276  10.342  0.961   1.00 160.85 ? 1026 MET A CA  1 
ATOM   7347  C C   . MET A 1 951 ? 22.541  9.963   -0.496  1.00 168.62 ? 1026 MET A C   1 
ATOM   7348  O O   . MET A 1 951 ? 22.858  10.839  -1.310  1.00 163.05 ? 1026 MET A O   1 
ATOM   7349  C CB  . MET A 1 951 ? 23.402  11.273  1.432   1.00 169.03 ? 1026 MET A CB  1 
ATOM   7350  C CG  . MET A 1 951 ? 24.823  10.909  1.012   1.00 175.80 ? 1026 MET A CG  1 
ATOM   7351  S SD  . MET A 1 951 ? 25.678  9.601   1.869   1.00 158.18 ? 1026 MET A SD  1 
ATOM   7352  C CE  . MET A 1 951 ? 26.007  10.479  3.389   1.00 141.89 ? 1026 MET A CE  1 
ATOM   7353  N N   . THR A 1 952 ? 22.410  8.689   -0.844  1.00 165.84 ? 1027 THR A N   1 
ATOM   7354  C CA  . THR A 1 952 ? 22.675  8.194   -2.200  1.00 151.23 ? 1027 THR A CA  1 
ATOM   7355  C C   . THR A 1 952 ? 24.130  8.512   -2.531  1.00 156.74 ? 1027 THR A C   1 
ATOM   7356  O O   . THR A 1 952 ? 25.028  7.987   -1.847  1.00 167.73 ? 1027 THR A O   1 
ATOM   7357  C CB  . THR A 1 952 ? 21.610  8.738   -3.182  1.00 141.11 ? 1027 THR A CB  1 
ATOM   7358  O OG1 . THR A 1 952 ? 21.808  10.142  -3.431  1.00 146.27 ? 1027 THR A OG1 1 
ATOM   7359  C CG2 . THR A 1 952 ? 20.199  8.534   -2.580  1.00 138.98 ? 1027 THR A CG2 1 
ATOM   7360  N N   . PHE A 1 953 ? 24.418  9.339   -3.524  1.00 154.26 ? 1028 PHE A N   1 
ATOM   7361  C CA  . PHE A 1 953 ? 25.746  9.737   -3.976  1.00 147.18 ? 1028 PHE A CA  1 
ATOM   7362  C C   . PHE A 1 953 ? 25.840  11.225  -4.287  1.00 151.44 ? 1028 PHE A C   1 
ATOM   7363  O O   . PHE A 1 953 ? 26.875  11.845  -4.016  1.00 162.92 ? 1028 PHE A O   1 
ATOM   7364  C CB  . PHE A 1 953 ? 26.111  8.922   -5.233  1.00 156.44 ? 1028 PHE A CB  1 
ATOM   7365  C CG  . PHE A 1 953 ? 27.535  9.066   -5.653  1.00 173.30 ? 1028 PHE A CG  1 
ATOM   7366  C CD1 . PHE A 1 953 ? 28.541  9.058   -4.713  1.00 169.15 ? 1028 PHE A CD1 1 
ATOM   7367  C CD2 . PHE A 1 953 ? 27.866  9.215   -6.994  1.00 167.07 ? 1028 PHE A CD2 1 
ATOM   7368  C CE1 . PHE A 1 953 ? 29.851  9.193   -5.090  1.00 160.73 ? 1028 PHE A CE1 1 
ATOM   7369  C CE2 . PHE A 1 953 ? 29.179  9.351   -7.373  1.00 142.52 ? 1028 PHE A CE2 1 
ATOM   7370  C CZ  . PHE A 1 953 ? 30.170  9.340   -6.423  1.00 139.05 ? 1028 PHE A CZ  1 
ATOM   7371  N N   . GLN A 1 954 ? 24.778  11.812  -4.849  1.00 158.64 ? 1029 GLN A N   1 
ATOM   7372  C CA  . GLN A 1 954 ? 24.798  13.229  -5.193  1.00 165.77 ? 1029 GLN A CA  1 
ATOM   7373  C C   . GLN A 1 954 ? 25.038  14.093  -3.962  1.00 170.56 ? 1029 GLN A C   1 
ATOM   7374  O O   . GLN A 1 954 ? 25.744  15.106  -4.032  1.00 165.84 ? 1029 GLN A O   1 
ATOM   7375  C CB  . GLN A 1 954 ? 23.479  13.635  -5.862  1.00 169.22 ? 1029 GLN A CB  1 
ATOM   7376  C CG  . GLN A 1 954 ? 23.215  12.974  -7.200  1.00 163.68 ? 1029 GLN A CG  1 
ATOM   7377  C CD  . GLN A 1 954 ? 21.750  13.026  -7.585  1.00 165.30 ? 1029 GLN A CD  1 
ATOM   7378  O OE1 . GLN A 1 954 ? 20.865  13.026  -6.727  1.00 175.48 ? 1029 GLN A OE1 1 
ATOM   7379  N NE2 . GLN A 1 954 ? 21.487  13.083  -8.883  1.00 159.15 ? 1029 GLN A NE2 1 
ATOM   7380  N N   . MET A 1 955 ? 24.460  13.707  -2.822  1.00 194.06 ? 1030 MET A N   1 
ATOM   7381  C CA  . MET A 1 955 ? 24.628  14.493  -1.603  1.00 205.61 ? 1030 MET A CA  1 
ATOM   7382  C C   . MET A 1 955 ? 26.071  14.456  -1.112  1.00 186.17 ? 1030 MET A C   1 
ATOM   7383  O O   . MET A 1 955 ? 26.600  15.472  -0.644  1.00 182.29 ? 1030 MET A O   1 
ATOM   7384  C CB  . MET A 1 955 ? 23.680  13.977  -0.523  1.00 202.37 ? 1030 MET A CB  1 
ATOM   7385  C CG  . MET A 1 955 ? 22.204  14.219  -0.793  1.00 188.96 ? 1030 MET A CG  1 
ATOM   7386  S SD  . MET A 1 955 ? 21.185  13.991  0.683   1.00 167.82 ? 1030 MET A SD  1 
ATOM   7387  C CE  . MET A 1 955 ? 22.237  14.666  1.965   1.00 183.75 ? 1030 MET A CE  1 
ATOM   7388  N N   . SER A 1 956 ? 26.724  13.294  -1.211  1.00 177.98 ? 1031 SER A N   1 
ATOM   7389  C CA  . SER A 1 956 ? 28.130  13.196  -0.831  1.00 168.40 ? 1031 SER A CA  1 
ATOM   7390  C C   . SER A 1 956 ? 29.007  14.108  -1.677  1.00 171.47 ? 1031 SER A C   1 
ATOM   7391  O O   . SER A 1 956 ? 30.041  14.590  -1.200  1.00 172.90 ? 1031 SER A O   1 
ATOM   7392  C CB  . SER A 1 956 ? 28.608  11.749  -0.951  1.00 155.08 ? 1031 SER A CB  1 
ATOM   7393  O OG  . SER A 1 956 ? 28.893  11.424  -2.300  1.00 152.98 ? 1031 SER A OG  1 
ATOM   7394  N N   . LEU A 1 957 ? 28.618  14.348  -2.931  1.00 178.57 ? 1032 LEU A N   1 
ATOM   7395  C CA  . LEU A 1 957 ? 29.335  15.296  -3.775  1.00 175.65 ? 1032 LEU A CA  1 
ATOM   7396  C C   . LEU A 1 957 ? 28.927  16.728  -3.463  1.00 177.35 ? 1032 LEU A C   1 
ATOM   7397  O O   . LEU A 1 957 ? 29.769  17.634  -3.473  1.00 170.35 ? 1032 LEU A O   1 
ATOM   7398  C CB  . LEU A 1 957 ? 29.076  14.991  -5.250  1.00 166.71 ? 1032 LEU A CB  1 
ATOM   7399  C CG  . LEU A 1 957 ? 29.119  13.517  -5.652  1.00 153.21 ? 1032 LEU A CG  1 
ATOM   7400  C CD1 . LEU A 1 957 ? 28.311  13.268  -6.918  1.00 158.21 ? 1032 LEU A CD1 1 
ATOM   7401  C CD2 . LEU A 1 957 ? 30.556  13.048  -5.832  1.00 120.66 ? 1032 LEU A CD2 1 
ATOM   7402  N N   . ARG A 1 958 ? 27.644  16.945  -3.184  1.00 182.99 ? 1033 ARG A N   1 
ATOM   7403  C CA  . ARG A 1 958 ? 27.109  18.280  -2.926  1.00 182.45 ? 1033 ARG A CA  1 
ATOM   7404  C C   . ARG A 1 958 ? 27.387  18.637  -1.470  1.00 184.50 ? 1033 ARG A C   1 
ATOM   7405  O O   . ARG A 1 958 ? 26.641  18.248  -0.566  1.00 211.76 ? 1033 ARG A O   1 
ATOM   7406  C CB  . ARG A 1 958 ? 25.621  18.322  -3.264  1.00 173.29 ? 1033 ARG A CB  1 
ATOM   7407  C CG  . ARG A 1 958 ? 24.839  19.488  -2.691  1.00 171.59 ? 1033 ARG A CG  1 
ATOM   7408  C CD  . ARG A 1 958 ? 23.682  19.852  -3.615  1.00 170.34 ? 1033 ARG A CD  1 
ATOM   7409  N NE  . ARG A 1 958 ? 22.471  19.106  -3.295  1.00 186.42 ? 1033 ARG A NE  1 
ATOM   7410  C CZ  . ARG A 1 958 ? 21.273  19.364  -3.801  1.00 195.41 ? 1033 ARG A CZ  1 
ATOM   7411  N NH1 . ARG A 1 958 ? 21.071  20.393  -4.607  1.00 185.97 ? 1033 ARG A NH1 1 
ATOM   7412  N NH2 . ARG A 1 958 ? 20.253  18.563  -3.500  1.00 221.37 ? 1033 ARG A NH2 1 
ATOM   7413  N N   . ARG A 1 959 ? 28.486  19.362  -1.231  1.00 166.18 ? 1034 ARG A N   1 
ATOM   7414  C CA  . ARG A 1 959 ? 28.783  19.852  0.110   1.00 177.94 ? 1034 ARG A CA  1 
ATOM   7415  C C   . ARG A 1 959 ? 29.681  21.087  0.058   1.00 171.75 ? 1034 ARG A C   1 
ATOM   7416  O O   . ARG A 1 959 ? 30.851  21.060  0.448   1.00 181.04 ? 1034 ARG A O   1 
ATOM   7417  C CB  . ARG A 1 959 ? 29.389  18.713  0.964   1.00 184.38 ? 1034 ARG A CB  1 
ATOM   7418  C CG  . ARG A 1 959 ? 30.813  18.296  0.671   1.00 183.15 ? 1034 ARG A CG  1 
ATOM   7419  C CD  . ARG A 1 959 ? 31.010  17.391  -0.510  1.00 168.82 ? 1034 ARG A CD  1 
ATOM   7420  N NE  . ARG A 1 959 ? 32.373  16.871  -0.536  1.00 162.18 ? 1034 ARG A NE  1 
ATOM   7421  C CZ  . ARG A 1 959 ? 32.908  16.211  -1.554  1.00 163.99 ? 1034 ARG A CZ  1 
ATOM   7422  N NH1 . ARG A 1 959 ? 32.220  15.961  -2.656  1.00 167.33 ? 1034 ARG A NH1 1 
ATOM   7423  N NH2 . ARG A 1 959 ? 34.160  15.773  -1.458  1.00 192.29 ? 1034 ARG A NH2 1 
ATOM   7424  N N   . GLU A 1 960 ? 29.114  22.203  -0.398  1.00 168.13 ? 1035 GLU A N   1 
ATOM   7425  C CA  . GLU A 1 960 ? 29.839  23.459  -0.474  1.00 183.44 ? 1035 GLU A CA  1 
ATOM   7426  C C   . GLU A 1 960 ? 29.290  24.538  0.449   1.00 184.76 ? 1035 GLU A C   1 
ATOM   7427  O O   . GLU A 1 960 ? 29.944  25.571  0.618   1.00 196.87 ? 1035 GLU A O   1 
ATOM   7428  C CB  . GLU A 1 960 ? 29.841  23.967  -1.925  1.00 193.90 ? 1035 GLU A CB  1 
ATOM   7429  C CG  . GLU A 1 960 ? 28.629  24.809  -2.315  1.00 196.73 ? 1035 GLU A CG  1 
ATOM   7430  C CD  . GLU A 1 960 ? 28.872  26.300  -2.153  1.00 199.05 ? 1035 GLU A CD  1 
ATOM   7431  O OE1 . GLU A 1 960 ? 30.038  26.724  -2.299  1.00 197.60 ? 1035 GLU A OE1 1 
ATOM   7432  O OE2 . GLU A 1 960 ? 27.906  27.044  -1.881  1.00 198.24 ? 1035 GLU A OE2 1 
ATOM   7433  N N   . ASP A 1 961 ? 28.120  24.330  1.044   1.00 174.76 ? 1036 ASP A N   1 
ATOM   7434  C CA  . ASP A 1 961 ? 27.506  25.359  1.873   1.00 181.65 ? 1036 ASP A CA  1 
ATOM   7435  C C   . ASP A 1 961 ? 27.032  24.794  3.209   1.00 177.90 ? 1036 ASP A C   1 
ATOM   7436  O O   . ASP A 1 961 ? 27.852  24.427  4.059   1.00 175.60 ? 1036 ASP A O   1 
ATOM   7437  C CB  . ASP A 1 961 ? 26.352  26.011  1.112   1.00 198.62 ? 1036 ASP A CB  1 
ATOM   7438  C CG  . ASP A 1 961 ? 26.146  27.454  1.501   1.00 210.09 ? 1036 ASP A CG  1 
ATOM   7439  O OD1 . ASP A 1 961 ? 25.616  27.697  2.607   1.00 209.51 ? 1036 ASP A OD1 1 
ATOM   7440  O OD2 . ASP A 1 961 ? 26.541  28.344  0.722   1.00 229.21 ? 1036 ASP A OD2 1 
ATOM   7441  N N   . VAL A 1 962 ? 25.711  24.736  3.403   1.00 178.98 ? 1037 VAL A N   1 
ATOM   7442  C CA  . VAL A 1 962 ? 25.094  24.198  4.612   1.00 174.83 ? 1037 VAL A CA  1 
ATOM   7443  C C   . VAL A 1 962 ? 25.146  22.679  4.680   1.00 163.81 ? 1037 VAL A C   1 
ATOM   7444  O O   . VAL A 1 962 ? 24.712  22.105  5.684   1.00 173.45 ? 1037 VAL A O   1 
ATOM   7445  C CB  . VAL A 1 962 ? 23.632  24.655  4.720   1.00 172.15 ? 1037 VAL A CB  1 
ATOM   7446  N N   . TRP A 1 963 ? 25.656  22.021  3.641   1.00 158.50 ? 1038 TRP A N   1 
ATOM   7447  C CA  . TRP A 1 963 ? 25.877  20.583  3.641   1.00 163.06 ? 1038 TRP A CA  1 
ATOM   7448  C C   . TRP A 1 963 ? 27.204  20.204  4.283   1.00 164.76 ? 1038 TRP A C   1 
ATOM   7449  O O   . TRP A 1 963 ? 27.576  19.025  4.267   1.00 159.03 ? 1038 TRP A O   1 
ATOM   7450  C CB  . TRP A 1 963 ? 25.794  20.036  2.209   1.00 175.24 ? 1038 TRP A CB  1 
ATOM   7451  C CG  . TRP A 1 963 ? 24.490  20.352  1.504   1.00 181.75 ? 1038 TRP A CG  1 
ATOM   7452  C CD1 . TRP A 1 963 ? 23.907  21.582  1.363   1.00 180.94 ? 1038 TRP A CD1 1 
ATOM   7453  C CD2 . TRP A 1 963 ? 23.605  19.420  0.871   1.00 188.71 ? 1038 TRP A CD2 1 
ATOM   7454  N NE1 . TRP A 1 963 ? 22.723  21.471  0.676   1.00 192.78 ? 1038 TRP A NE1 1 
ATOM   7455  C CE2 . TRP A 1 963 ? 22.514  20.154  0.363   1.00 195.54 ? 1038 TRP A CE2 1 
ATOM   7456  C CE3 . TRP A 1 963 ? 23.631  18.036  0.682   1.00 180.99 ? 1038 TRP A CE3 1 
ATOM   7457  C CZ2 . TRP A 1 963 ? 21.460  19.550  -0.320  1.00 198.85 ? 1038 TRP A CZ2 1 
ATOM   7458  C CZ3 . TRP A 1 963 ? 22.587  17.442  0.002   1.00 185.35 ? 1038 TRP A CZ3 1 
ATOM   7459  C CH2 . TRP A 1 963 ? 21.516  18.195  -0.487  1.00 196.01 ? 1038 TRP A CH2 1 
ATOM   7460  N N   . LEU A 1 964 ? 27.911  21.187  4.843   1.00 167.33 ? 1039 LEU A N   1 
ATOM   7461  C CA  . LEU A 1 964 ? 29.172  20.916  5.531   1.00 168.72 ? 1039 LEU A CA  1 
ATOM   7462  C C   . LEU A 1 964 ? 29.034  20.013  6.751   1.00 161.39 ? 1039 LEU A C   1 
ATOM   7463  O O   . LEU A 1 964 ? 29.985  19.265  7.027   1.00 155.28 ? 1039 LEU A O   1 
ATOM   7464  C CB  . LEU A 1 964 ? 29.850  22.232  5.932   1.00 172.37 ? 1039 LEU A CB  1 
ATOM   7465  C CG  . LEU A 1 964 ? 30.832  22.868  4.941   1.00 165.28 ? 1039 LEU A CG  1 
ATOM   7466  C CD1 . LEU A 1 964 ? 32.163  22.147  5.002   1.00 148.86 ? 1039 LEU A CD1 1 
ATOM   7467  C CD2 . LEU A 1 964 ? 30.303  22.877  3.532   1.00 166.65 ? 1039 LEU A CD2 1 
ATOM   7468  N N   . PRO A 1 965 ? 27.956  20.057  7.546   1.00 161.70 ? 1040 PRO A N   1 
ATOM   7469  C CA  . PRO A 1 965 ? 27.831  19.049  8.618   1.00 154.52 ? 1040 PRO A CA  1 
ATOM   7470  C C   . PRO A 1 965 ? 27.827  17.627  8.088   1.00 143.39 ? 1040 PRO A C   1 
ATOM   7471  O O   . PRO A 1 965 ? 28.444  16.734  8.687   1.00 142.01 ? 1040 PRO A O   1 
ATOM   7472  C CB  . PRO A 1 965 ? 26.506  19.427  9.286   1.00 146.36 ? 1040 PRO A CB  1 
ATOM   7473  C CG  . PRO A 1 965 ? 26.388  20.887  9.066   1.00 144.47 ? 1040 PRO A CG  1 
ATOM   7474  C CD  . PRO A 1 965 ? 26.975  21.147  7.709   1.00 161.35 ? 1040 PRO A CD  1 
ATOM   7475  N N   . LEU A 1 966 ? 27.143  17.399  6.966   1.00 145.03 ? 1041 LEU A N   1 
ATOM   7476  C CA  . LEU A 1 966 ? 27.146  16.080  6.346   1.00 143.95 ? 1041 LEU A CA  1 
ATOM   7477  C C   . LEU A 1 966 ? 28.562  15.652  5.980   1.00 151.76 ? 1041 LEU A C   1 
ATOM   7478  O O   . LEU A 1 966 ? 28.970  14.517  6.245   1.00 150.89 ? 1041 LEU A O   1 
ATOM   7479  C CB  . LEU A 1 966 ? 26.245  16.087  5.112   1.00 144.24 ? 1041 LEU A CB  1 
ATOM   7480  C CG  . LEU A 1 966 ? 26.462  14.947  4.118   1.00 141.22 ? 1041 LEU A CG  1 
ATOM   7481  C CD1 . LEU A 1 966 ? 25.917  13.655  4.687   1.00 138.05 ? 1041 LEU A CD1 1 
ATOM   7482  C CD2 . LEU A 1 966 ? 25.825  15.272  2.771   1.00 156.88 ? 1041 LEU A CD2 1 
ATOM   7483  N N   . MET A 1 967 ? 29.334  16.566  5.387   1.00 157.48 ? 1042 MET A N   1 
ATOM   7484  C CA  . MET A 1 967 ? 30.704  16.261  4.979   1.00 155.89 ? 1042 MET A CA  1 
ATOM   7485  C C   . MET A 1 967 ? 31.615  16.060  6.187   1.00 152.39 ? 1042 MET A C   1 
ATOM   7486  O O   . MET A 1 967 ? 32.524  15.225  6.149   1.00 149.77 ? 1042 MET A O   1 
ATOM   7487  C CB  . MET A 1 967 ? 31.211  17.370  4.051   1.00 156.52 ? 1042 MET A CB  1 
ATOM   7488  C CG  . MET A 1 967 ? 32.441  17.061  3.205   1.00 165.05 ? 1042 MET A CG  1 
ATOM   7489  S SD  . MET A 1 967 ? 33.481  18.540  3.077   1.00 196.55 ? 1042 MET A SD  1 
ATOM   7490  C CE  . MET A 1 967 ? 34.888  18.196  4.125   1.00 167.30 ? 1042 MET A CE  1 
ATOM   7491  N N   . SER A 1 968 ? 31.372  16.785  7.281   1.00 145.64 ? 1043 SER A N   1 
ATOM   7492  C CA  . SER A 1 968 ? 32.184  16.599  8.482   1.00 136.08 ? 1043 SER A CA  1 
ATOM   7493  C C   . SER A 1 968 ? 31.929  15.230  9.101   1.00 137.04 ? 1043 SER A C   1 
ATOM   7494  O O   . SER A 1 968 ? 32.870  14.519  9.476   1.00 136.50 ? 1043 SER A O   1 
ATOM   7495  C CB  . SER A 1 968 ? 31.897  17.716  9.484   1.00 130.85 ? 1043 SER A CB  1 
ATOM   7496  O OG  . SER A 1 968 ? 30.696  17.466  10.192  1.00 146.43 ? 1043 SER A OG  1 
ATOM   7497  N N   . TYR A 1 969 ? 30.656  14.838  9.204   1.00 143.39 ? 1044 TYR A N   1 
ATOM   7498  C CA  . TYR A 1 969 ? 30.337  13.503  9.696   1.00 139.56 ? 1044 TYR A CA  1 
ATOM   7499  C C   . TYR A 1 969 ? 30.884  12.435  8.757   1.00 136.05 ? 1044 TYR A C   1 
ATOM   7500  O O   . TYR A 1 969 ? 31.340  11.376  9.205   1.00 121.46 ? 1044 TYR A O   1 
ATOM   7501  C CB  . TYR A 1 969 ? 28.826  13.355  9.863   1.00 133.19 ? 1044 TYR A CB  1 
ATOM   7502  C CG  . TYR A 1 969 ? 28.376  11.975  10.296  1.00 126.01 ? 1044 TYR A CG  1 
ATOM   7503  C CD1 . TYR A 1 969 ? 28.734  11.466  11.539  1.00 116.98 ? 1044 TYR A CD1 1 
ATOM   7504  C CD2 . TYR A 1 969 ? 27.590  11.184  9.470   1.00 131.18 ? 1044 TYR A CD2 1 
ATOM   7505  C CE1 . TYR A 1 969 ? 28.320  10.210  11.944  1.00 105.75 ? 1044 TYR A CE1 1 
ATOM   7506  C CE2 . TYR A 1 969 ? 27.175  9.927   9.868   1.00 122.72 ? 1044 TYR A CE2 1 
ATOM   7507  C CZ  . TYR A 1 969 ? 27.545  9.443   11.101  1.00 106.49 ? 1044 TYR A CZ  1 
ATOM   7508  O OH  . TYR A 1 969 ? 27.130  8.190   11.490  1.00 107.35 ? 1044 TYR A OH  1 
ATOM   7509  N N   . ARG A 1 970 ? 30.863  12.707  7.449   1.00 143.09 ? 1045 ARG A N   1 
ATOM   7510  C CA  . ARG A 1 970 ? 31.366  11.750  6.470   1.00 150.51 ? 1045 ARG A CA  1 
ATOM   7511  C C   . ARG A 1 970 ? 32.870  11.553  6.615   1.00 152.07 ? 1045 ARG A C   1 
ATOM   7512  O O   . ARG A 1 970 ? 33.371  10.428  6.495   1.00 148.51 ? 1045 ARG A O   1 
ATOM   7513  C CB  . ARG A 1 970 ? 31.004  12.234  5.063   1.00 161.05 ? 1045 ARG A CB  1 
ATOM   7514  C CG  . ARG A 1 970 ? 30.456  11.157  4.147   1.00 179.20 ? 1045 ARG A CG  1 
ATOM   7515  C CD  . ARG A 1 970 ? 30.121  11.714  2.767   1.00 198.62 ? 1045 ARG A CD  1 
ATOM   7516  N NE  . ARG A 1 970 ? 31.277  12.276  2.079   1.00 194.94 ? 1045 ARG A NE  1 
ATOM   7517  C CZ  . ARG A 1 970 ? 32.181  11.567  1.418   1.00 179.49 ? 1045 ARG A CZ  1 
ATOM   7518  N NH1 . ARG A 1 970 ? 32.100  10.250  1.331   1.00 175.03 ? 1045 ARG A NH1 1 
ATOM   7519  N NH2 . ARG A 1 970 ? 33.192  12.197  0.825   1.00 171.63 ? 1045 ARG A NH2 1 
ATOM   7520  N N   . ASN A 1 971 ? 33.604  12.638  6.874   1.00 149.55 ? 1046 ASN A N   1 
ATOM   7521  C CA  . ASN A 1 971 ? 35.039  12.531  7.123   1.00 145.39 ? 1046 ASN A CA  1 
ATOM   7522  C C   . ASN A 1 971 ? 35.312  11.792  8.424   1.00 136.99 ? 1046 ASN A C   1 
ATOM   7523  O O   . ASN A 1 971 ? 36.201  10.934  8.489   1.00 135.85 ? 1046 ASN A O   1 
ATOM   7524  C CB  . ASN A 1 971 ? 35.671  13.918  7.186   1.00 152.56 ? 1046 ASN A CB  1 
ATOM   7525  C CG  . ASN A 1 971 ? 35.520  14.685  5.908   1.00 157.70 ? 1046 ASN A CG  1 
ATOM   7526  O OD1 . ASN A 1 971 ? 35.250  15.878  5.934   1.00 164.94 ? 1046 ASN A OD1 1 
ATOM   7527  N ND2 . ASN A 1 971 ? 35.688  14.009  4.778   1.00 150.91 ? 1046 ASN A ND2 1 
ATOM   7528  N N   . SER A 1 972 ? 34.569  12.139  9.480   1.00 133.27 ? 1047 SER A N   1 
ATOM   7529  C CA  . SER A 1 972 ? 34.741  11.471  10.764  1.00 114.93 ? 1047 SER A CA  1 
ATOM   7530  C C   . SER A 1 972 ? 34.572  9.965   10.629  1.00 107.71 ? 1047 SER A C   1 
ATOM   7531  O O   . SER A 1 972 ? 35.139  9.201   11.420  1.00 96.95  ? 1047 SER A O   1 
ATOM   7532  C CB  . SER A 1 972 ? 33.746  12.033  11.782  1.00 116.43 ? 1047 SER A CB  1 
ATOM   7533  O OG  . SER A 1 972 ? 33.653  13.445  11.687  1.00 125.66 ? 1047 SER A OG  1 
ATOM   7534  N N   . LEU A 1 973 ? 33.815  9.523   9.631   1.00 116.72 ? 1048 LEU A N   1 
ATOM   7535  C CA  . LEU A 1 973 ? 33.647  8.108   9.345   1.00 126.98 ? 1048 LEU A CA  1 
ATOM   7536  C C   . LEU A 1 973 ? 34.818  7.577   8.524   1.00 131.03 ? 1048 LEU A C   1 
ATOM   7537  O O   . LEU A 1 973 ? 35.249  6.439   8.700   1.00 144.47 ? 1048 LEU A O   1 
ATOM   7538  C CB  . LEU A 1 973 ? 32.334  7.866   8.598   1.00 144.28 ? 1048 LEU A CB  1 
ATOM   7539  C CG  . LEU A 1 973 ? 31.092  7.615   9.455   1.00 128.81 ? 1048 LEU A CG  1 
ATOM   7540  C CD1 . LEU A 1 973 ? 31.137  6.198   9.969   1.00 123.42 ? 1048 LEU A CD1 1 
ATOM   7541  C CD2 . LEU A 1 973 ? 30.962  8.598   10.606  1.00 112.62 ? 1048 LEU A CD2 1 
ATOM   7542  N N   . LYS B 2 44  ? 67.695  20.933  23.130  1.00 105.89 ? 321  LYS B N   1 
ATOM   7543  C CA  . LYS B 2 44  ? 69.102  20.828  23.484  1.00 109.32 ? 321  LYS B CA  1 
ATOM   7544  C C   . LYS B 2 44  ? 69.252  19.832  24.632  1.00 118.65 ? 321  LYS B C   1 
ATOM   7545  O O   . LYS B 2 44  ? 68.719  18.724  24.564  1.00 113.64 ? 321  LYS B O   1 
ATOM   7546  C CB  . LYS B 2 44  ? 69.660  22.204  23.851  1.00 109.93 ? 321  LYS B CB  1 
ATOM   7547  C CG  . LYS B 2 44  ? 70.123  22.995  22.633  1.00 112.10 ? 321  LYS B CG  1 
ATOM   7548  C CD  . LYS B 2 44  ? 70.139  24.494  22.885  1.00 116.56 ? 321  LYS B CD  1 
ATOM   7549  C CE  . LYS B 2 44  ? 70.926  25.216  21.798  1.00 123.33 ? 321  LYS B CE  1 
ATOM   7550  N NZ  . LYS B 2 44  ? 71.031  26.683  22.035  1.00 113.19 ? 321  LYS B NZ  1 
ATOM   7551  N N   . ARG B 2 45  ? 69.966  20.215  25.686  1.00 124.92 ? 322  ARG B N   1 
ATOM   7552  C CA  . ARG B 2 45  ? 70.129  19.321  26.821  1.00 108.84 ? 322  ARG B CA  1 
ATOM   7553  C C   . ARG B 2 45  ? 68.922  19.411  27.749  1.00 107.63 ? 322  ARG B C   1 
ATOM   7554  O O   . ARG B 2 45  ? 68.241  20.439  27.822  1.00 105.11 ? 322  ARG B O   1 
ATOM   7555  C CB  . ARG B 2 45  ? 71.410  19.646  27.593  1.00 100.50 ? 322  ARG B CB  1 
ATOM   7556  C CG  . ARG B 2 45  ? 72.684  19.175  26.908  1.00 104.69 ? 322  ARG B CG  1 
ATOM   7557  C CD  . ARG B 2 45  ? 73.877  19.273  27.844  1.00 101.64 ? 322  ARG B CD  1 
ATOM   7558  N NE  . ARG B 2 45  ? 73.974  20.576  28.491  1.00 95.39  ? 322  ARG B NE  1 
ATOM   7559  C CZ  . ARG B 2 45  ? 75.016  20.977  29.205  1.00 108.75 ? 322  ARG B CZ  1 
ATOM   7560  N NH1 . ARG B 2 45  ? 76.056  20.186  29.412  1.00 111.39 ? 322  ARG B NH1 1 
ATOM   7561  N NH2 . ARG B 2 45  ? 75.011  22.198  29.732  1.00 114.96 ? 322  ARG B NH2 1 
ATOM   7562  N N   . LYS B 2 46  ? 68.654  18.315  28.457  1.00 109.21 ? 323  LYS B N   1 
ATOM   7563  C CA  . LYS B 2 46  ? 67.559  18.270  29.417  1.00 103.36 ? 323  LYS B CA  1 
ATOM   7564  C C   . LYS B 2 46  ? 67.951  18.794  30.792  1.00 96.99  ? 323  LYS B C   1 
ATOM   7565  O O   . LYS B 2 46  ? 67.109  18.796  31.696  1.00 80.69  ? 323  LYS B O   1 
ATOM   7566  C CB  . LYS B 2 46  ? 67.020  16.840  29.555  1.00 93.72  ? 323  LYS B CB  1 
ATOM   7567  C CG  . LYS B 2 46  ? 67.178  15.974  28.317  1.00 95.10  ? 323  LYS B CG  1 
ATOM   7568  C CD  . LYS B 2 46  ? 65.992  16.140  27.379  1.00 116.70 ? 323  LYS B CD  1 
ATOM   7569  C CE  . LYS B 2 46  ? 64.777  15.364  27.867  1.00 118.51 ? 323  LYS B CE  1 
ATOM   7570  N NZ  . LYS B 2 46  ? 64.991  13.893  27.803  1.00 115.93 ? 323  LYS B NZ  1 
ATOM   7571  N N   . LEU B 2 47  ? 69.196  19.234  30.971  1.00 98.62  ? 324  LEU B N   1 
ATOM   7572  C CA  . LEU B 2 47  ? 69.634  19.735  32.266  1.00 92.84  ? 324  LEU B CA  1 
ATOM   7573  C C   . LEU B 2 47  ? 68.833  20.967  32.664  1.00 83.49  ? 324  LEU B C   1 
ATOM   7574  O O   . LEU B 2 47  ? 68.590  21.863  31.851  1.00 87.07  ? 324  LEU B O   1 
ATOM   7575  C CB  . LEU B 2 47  ? 71.123  20.072  32.227  1.00 88.33  ? 324  LEU B CB  1 
ATOM   7576  C CG  . LEU B 2 47  ? 71.797  20.551  33.514  1.00 83.71  ? 324  LEU B CG  1 
ATOM   7577  C CD1 . LEU B 2 47  ? 71.658  19.517  34.621  1.00 94.50  ? 324  LEU B CD1 1 
ATOM   7578  C CD2 . LEU B 2 47  ? 73.259  20.860  33.247  1.00 76.20  ? 324  LEU B CD2 1 
ATOM   7579  N N   . ILE B 2 48  ? 68.424  21.007  33.928  1.00 83.93  ? 325  ILE B N   1 
ATOM   7580  C CA  . ILE B 2 48  ? 67.588  22.089  34.436  1.00 76.24  ? 325  ILE B CA  1 
ATOM   7581  C C   . ILE B 2 48  ? 68.482  23.290  34.725  1.00 74.13  ? 325  ILE B C   1 
ATOM   7582  O O   . ILE B 2 48  ? 69.322  23.250  35.627  1.00 78.78  ? 325  ILE B O   1 
ATOM   7583  C CB  . ILE B 2 48  ? 66.815  21.656  35.685  1.00 69.07  ? 325  ILE B CB  1 
ATOM   7584  C CG1 . ILE B 2 48  ? 66.350  20.205  35.532  1.00 66.84  ? 325  ILE B CG1 1 
ATOM   7585  C CG2 . ILE B 2 48  ? 65.638  22.586  35.926  1.00 59.01  ? 325  ILE B CG2 1 
ATOM   7586  C CD1 . ILE B 2 48  ? 65.303  19.784  36.535  1.00 75.07  ? 325  ILE B CD1 1 
ATOM   7587  N N   . VAL B 2 49  ? 68.306  24.360  33.953  1.00 65.47  ? 326  VAL B N   1 
ATOM   7588  C CA  . VAL B 2 49  ? 69.057  25.598  34.122  1.00 74.42  ? 326  VAL B CA  1 
ATOM   7589  C C   . VAL B 2 49  ? 68.049  26.712  34.367  1.00 74.87  ? 326  VAL B C   1 
ATOM   7590  O O   . VAL B 2 49  ? 67.287  27.080  33.463  1.00 85.04  ? 326  VAL B O   1 
ATOM   7591  C CB  . VAL B 2 49  ? 69.937  25.912  32.904  1.00 73.02  ? 326  VAL B CB  1 
ATOM   7592  C CG1 . VAL B 2 49  ? 70.936  27.008  33.241  1.00 67.13  ? 326  VAL B CG1 1 
ATOM   7593  C CG2 . VAL B 2 49  ? 70.650  24.658  32.419  1.00 63.17  ? 326  VAL B CG2 1 
ATOM   7594  N N   . ASP B 2 50  ? 68.040  27.250  35.585  1.00 72.50  ? 327  ASP B N   1 
ATOM   7595  C CA  . ASP B 2 50  ? 67.126  28.325  35.960  1.00 79.04  ? 327  ASP B CA  1 
ATOM   7596  C C   . ASP B 2 50  ? 67.801  29.664  35.684  1.00 74.86  ? 327  ASP B C   1 
ATOM   7597  O O   . ASP B 2 50  ? 68.801  30.008  36.323  1.00 82.40  ? 327  ASP B O   1 
ATOM   7598  C CB  . ASP B 2 50  ? 66.722  28.200  37.427  1.00 78.04  ? 327  ASP B CB  1 
ATOM   7599  C CG  . ASP B 2 50  ? 66.118  26.847  37.749  1.00 84.89  ? 327  ASP B CG  1 
ATOM   7600  O OD1 . ASP B 2 50  ? 65.944  26.039  36.813  1.00 82.39  ? 327  ASP B OD1 1 
ATOM   7601  O OD2 . ASP B 2 50  ? 65.821  26.590  38.935  1.00 77.12  ? 327  ASP B OD2 1 
ATOM   7602  N N   . SER B 2 51  ? 67.249  30.421  34.731  1.00 66.30  ? 328  SER B N   1 
ATOM   7603  C CA  . SER B 2 51  ? 67.827  31.714  34.381  1.00 69.54  ? 328  SER B CA  1 
ATOM   7604  C C   . SER B 2 51  ? 67.715  32.703  35.535  1.00 80.04  ? 328  SER B C   1 
ATOM   7605  O O   . SER B 2 51  ? 68.636  33.492  35.775  1.00 88.20  ? 328  SER B O   1 
ATOM   7606  C CB  . SER B 2 51  ? 67.151  32.267  33.127  1.00 74.67  ? 328  SER B CB  1 
ATOM   7607  O OG  . SER B 2 51  ? 65.750  32.378  33.304  1.00 88.63  ? 328  SER B OG  1 
ATOM   7608  N N   . VAL B 2 52  ? 66.600  32.675  36.259  1.00 88.08  ? 329  VAL B N   1 
ATOM   7609  C CA  . VAL B 2 52  ? 66.398  33.513  37.434  1.00 91.61  ? 329  VAL B CA  1 
ATOM   7610  C C   . VAL B 2 52  ? 66.422  32.601  38.653  1.00 93.38  ? 329  VAL B C   1 
ATOM   7611  O O   . VAL B 2 52  ? 65.496  31.811  38.871  1.00 92.37  ? 329  VAL B O   1 
ATOM   7612  C CB  . VAL B 2 52  ? 65.089  34.310  37.356  1.00 87.56  ? 329  VAL B CB  1 
ATOM   7613  C CG1 . VAL B 2 52  ? 65.150  35.517  38.281  1.00 90.01  ? 329  VAL B CG1 1 
ATOM   7614  C CG2 . VAL B 2 52  ? 64.829  34.751  35.927  1.00 94.02  ? 329  VAL B CG2 1 
ATOM   7615  N N   . LYS B 2 53  ? 67.487  32.709  39.443  1.00 82.49  ? 330  LYS B N   1 
ATOM   7616  C CA  . LYS B 2 53  ? 67.671  31.892  40.634  1.00 85.92  ? 330  LYS B CA  1 
ATOM   7617  C C   . LYS B 2 53  ? 67.054  32.509  41.879  1.00 86.90  ? 330  LYS B C   1 
ATOM   7618  O O   . LYS B 2 53  ? 66.955  31.829  42.905  1.00 80.34  ? 330  LYS B O   1 
ATOM   7619  C CB  . LYS B 2 53  ? 69.166  31.666  40.882  1.00 88.05  ? 330  LYS B CB  1 
ATOM   7620  C CG  . LYS B 2 53  ? 69.976  31.423  39.620  1.00 93.45  ? 330  LYS B CG  1 
ATOM   7621  C CD  . LYS B 2 53  ? 71.420  31.846  39.816  1.00 80.79  ? 330  LYS B CD  1 
ATOM   7622  C CE  . LYS B 2 53  ? 71.504  33.323  40.168  1.00 96.66  ? 330  LYS B CE  1 
ATOM   7623  N NZ  . LYS B 2 53  ? 72.909  33.804  40.247  1.00 101.87 ? 330  LYS B NZ  1 
ATOM   7624  N N   . GLU B 2 54  ? 66.636  33.770  41.815  1.00 85.13  ? 331  GLU B N   1 
ATOM   7625  C CA  . GLU B 2 54  ? 66.274  34.528  42.999  1.00 73.18  ? 331  GLU B CA  1 
ATOM   7626  C C   . GLU B 2 54  ? 64.944  35.233  42.794  1.00 82.38  ? 331  GLU B C   1 
ATOM   7627  O O   . GLU B 2 54  ? 64.587  35.610  41.674  1.00 97.02  ? 331  GLU B O   1 
ATOM   7628  C CB  . GLU B 2 54  ? 67.343  35.572  43.329  1.00 84.85  ? 331  GLU B CB  1 
ATOM   7629  C CG  . GLU B 2 54  ? 68.426  35.096  44.274  1.00 102.93 ? 331  GLU B CG  1 
ATOM   7630  C CD  . GLU B 2 54  ? 69.113  36.255  44.956  1.00 103.95 ? 331  GLU B CD  1 
ATOM   7631  O OE1 . GLU B 2 54  ? 68.391  37.164  45.414  1.00 90.93  ? 331  GLU B OE1 1 
ATOM   7632  O OE2 . GLU B 2 54  ? 70.362  36.268  45.020  1.00 96.48  ? 331  GLU B OE2 1 
ATOM   7633  N N   . LEU B 2 55  ? 64.219  35.418  43.893  1.00 74.17  ? 332  LEU B N   1 
ATOM   7634  C CA  . LEU B 2 55  ? 63.054  36.290  43.897  1.00 69.78  ? 332  LEU B CA  1 
ATOM   7635  C C   . LEU B 2 55  ? 63.527  37.729  44.065  1.00 77.58  ? 332  LEU B C   1 
ATOM   7636  O O   . LEU B 2 55  ? 64.225  38.048  45.034  1.00 76.40  ? 332  LEU B O   1 
ATOM   7637  C CB  . LEU B 2 55  ? 62.088  35.896  45.014  1.00 65.24  ? 332  LEU B CB  1 
ATOM   7638  C CG  . LEU B 2 55  ? 61.805  34.400  45.189  1.00 50.49  ? 332  LEU B CG  1 
ATOM   7639  C CD1 . LEU B 2 55  ? 60.852  34.157  46.351  1.00 41.38  ? 332  LEU B CD1 1 
ATOM   7640  C CD2 . LEU B 2 55  ? 61.247  33.815  43.907  1.00 63.05  ? 332  LEU B CD2 1 
ATOM   7641  N N   . ASP B 2 56  ? 63.162  38.593  43.121  1.00 71.34  ? 333  ASP B N   1 
ATOM   7642  C CA  . ASP B 2 56  ? 63.582  39.984  43.188  1.00 77.82  ? 333  ASP B CA  1 
ATOM   7643  C C   . ASP B 2 56  ? 62.976  40.668  44.410  1.00 81.62  ? 333  ASP B C   1 
ATOM   7644  O O   . ASP B 2 56  ? 61.965  40.230  44.967  1.00 85.09  ? 333  ASP B O   1 
ATOM   7645  C CB  . ASP B 2 56  ? 63.185  40.727  41.912  1.00 82.56  ? 333  ASP B CB  1 
ATOM   7646  C CG  . ASP B 2 56  ? 61.710  40.590  41.595  1.00 93.86  ? 333  ASP B CG  1 
ATOM   7647  O OD1 . ASP B 2 56  ? 60.905  41.359  42.161  1.00 90.82  ? 333  ASP B OD1 1 
ATOM   7648  O OD2 . ASP B 2 56  ? 61.356  39.711  40.780  1.00 108.42 ? 333  ASP B OD2 1 
ATOM   7649  N N   . SER B 2 57  ? 63.618  41.761  44.829  1.00 77.94  ? 334  SER B N   1 
ATOM   7650  C CA  . SER B 2 57  ? 63.167  42.472  46.021  1.00 75.45  ? 334  SER B CA  1 
ATOM   7651  C C   . SER B 2 57  ? 61.743  42.989  45.863  1.00 76.64  ? 334  SER B C   1 
ATOM   7652  O O   . SER B 2 57  ? 61.002  43.080  46.850  1.00 67.28  ? 334  SER B O   1 
ATOM   7653  C CB  . SER B 2 57  ? 64.123  43.624  46.331  1.00 96.69  ? 334  SER B CB  1 
ATOM   7654  O OG  . SER B 2 57  ? 65.473  43.225  46.156  1.00 101.30 ? 334  SER B OG  1 
ATOM   7655  N N   . LYS B 2 58  ? 61.339  43.324  44.635  1.00 83.86  ? 335  LYS B N   1 
ATOM   7656  C CA  . LYS B 2 58  ? 59.980  43.808  44.421  1.00 83.74  ? 335  LYS B CA  1 
ATOM   7657  C C   . LYS B 2 58  ? 58.960  42.708  44.685  1.00 82.86  ? 335  LYS B C   1 
ATOM   7658  O O   . LYS B 2 58  ? 57.913  42.958  45.292  1.00 81.81  ? 335  LYS B O   1 
ATOM   7659  C CB  . LYS B 2 58  ? 59.827  44.352  43.000  1.00 92.66  ? 335  LYS B CB  1 
ATOM   7660  C CG  . LYS B 2 58  ? 58.534  43.934  42.313  1.00 95.43  ? 335  LYS B CG  1 
ATOM   7661  C CD  . LYS B 2 58  ? 58.483  44.408  40.873  1.00 93.78  ? 335  LYS B CD  1 
ATOM   7662  C CE  . LYS B 2 58  ? 59.202  43.440  39.945  1.00 102.69 ? 335  LYS B CE  1 
ATOM   7663  N NZ  . LYS B 2 58  ? 58.358  42.256  39.612  1.00 121.02 ? 335  LYS B NZ  1 
ATOM   7664  N N   . THR B 2 59  ? 59.255  41.479  44.250  1.00 70.03  ? 336  THR B N   1 
ATOM   7665  C CA  . THR B 2 59  ? 58.331  40.380  44.503  1.00 69.12  ? 336  THR B CA  1 
ATOM   7666  C C   . THR B 2 59  ? 58.268  40.030  45.983  1.00 71.87  ? 336  THR B C   1 
ATOM   7667  O O   . THR B 2 59  ? 57.203  39.656  46.481  1.00 81.87  ? 336  THR B O   1 
ATOM   7668  C CB  . THR B 2 59  ? 58.720  39.151  43.680  1.00 62.39  ? 336  THR B CB  1 
ATOM   7669  O OG1 . THR B 2 59  ? 60.140  38.975  43.715  1.00 84.79  ? 336  THR B OG1 1 
ATOM   7670  C CG2 . THR B 2 59  ? 58.263  39.307  42.235  1.00 77.08  ? 336  THR B CG2 1 
ATOM   7671  N N   . ILE B 2 60  ? 59.382  40.161  46.705  1.00 60.89  ? 337  ILE B N   1 
ATOM   7672  C CA  . ILE B 2 60  ? 59.355  39.920  48.145  1.00 63.81  ? 337  ILE B CA  1 
ATOM   7673  C C   . ILE B 2 60  ? 58.532  40.992  48.850  1.00 69.31  ? 337  ILE B C   1 
ATOM   7674  O O   . ILE B 2 60  ? 57.745  40.698  49.762  1.00 72.12  ? 337  ILE B O   1 
ATOM   7675  C CB  . ILE B 2 60  ? 60.789  39.849  48.698  1.00 65.52  ? 337  ILE B CB  1 
ATOM   7676  C CG1 . ILE B 2 60  ? 61.586  38.773  47.958  1.00 63.11  ? 337  ILE B CG1 1 
ATOM   7677  C CG2 . ILE B 2 60  ? 60.766  39.587  50.197  1.00 61.41  ? 337  ILE B CG2 1 
ATOM   7678  C CD1 . ILE B 2 60  ? 62.938  38.476  48.566  1.00 66.33  ? 337  ILE B CD1 1 
ATOM   7679  N N   . ARG B 2 61  ? 58.695  42.251  48.437  1.00 62.98  ? 338  ARG B N   1 
ATOM   7680  C CA  . ARG B 2 61  ? 57.877  43.318  49.000  1.00 75.62  ? 338  ARG B CA  1 
ATOM   7681  C C   . ARG B 2 61  ? 56.401  43.105  48.685  1.00 83.35  ? 338  ARG B C   1 
ATOM   7682  O O   . ARG B 2 61  ? 55.531  43.426  49.502  1.00 78.47  ? 338  ARG B O   1 
ATOM   7683  C CB  . ARG B 2 61  ? 58.346  44.673  48.476  1.00 77.55  ? 338  ARG B CB  1 
ATOM   7684  C CG  . ARG B 2 61  ? 59.481  45.292  49.270  1.00 82.07  ? 338  ARG B CG  1 
ATOM   7685  C CD  . ARG B 2 61  ? 60.429  46.060  48.362  1.00 80.83  ? 338  ARG B CD  1 
ATOM   7686  N NE  . ARG B 2 61  ? 61.507  46.693  49.112  1.00 84.87  ? 338  ARG B NE  1 
ATOM   7687  C CZ  . ARG B 2 61  ? 62.711  46.952  48.622  1.00 100.24 ? 338  ARG B CZ  1 
ATOM   7688  N NH1 . ARG B 2 61  ? 63.023  46.665  47.369  1.00 104.04 ? 338  ARG B NH1 1 
ATOM   7689  N NH2 . ARG B 2 61  ? 63.624  47.516  49.408  1.00 97.19  ? 338  ARG B NH2 1 
ATOM   7690  N N   . ALA B 2 62  ? 56.098  42.565  47.503  1.00 72.56  ? 339  ALA B N   1 
ATOM   7691  C CA  . ALA B 2 62  ? 54.710  42.285  47.152  1.00 72.17  ? 339  ALA B CA  1 
ATOM   7692  C C   . ALA B 2 62  ? 54.150  41.141  47.988  1.00 77.85  ? 339  ALA B C   1 
ATOM   7693  O O   . ALA B 2 62  ? 52.993  41.188  48.422  1.00 89.53  ? 339  ALA B O   1 
ATOM   7694  C CB  . ALA B 2 62  ? 54.601  41.967  45.661  1.00 67.10  ? 339  ALA B CB  1 
ATOM   7695  N N   . GLN B 2 63  ? 54.955  40.099  48.208  1.00 68.22  ? 340  GLN B N   1 
ATOM   7696  C CA  . GLN B 2 63  ? 54.561  39.021  49.109  1.00 67.77  ? 340  GLN B CA  1 
ATOM   7697  C C   . GLN B 2 63  ? 54.249  39.560  50.499  1.00 71.47  ? 340  GLN B C   1 
ATOM   7698  O O   . GLN B 2 63  ? 53.276  39.139  51.136  1.00 68.13  ? 340  GLN B O   1 
ATOM   7699  C CB  . GLN B 2 63  ? 55.674  37.976  49.185  1.00 65.72  ? 340  GLN B CB  1 
ATOM   7700  C CG  . GLN B 2 63  ? 55.923  37.204  47.900  1.00 57.89  ? 340  GLN B CG  1 
ATOM   7701  C CD  . GLN B 2 63  ? 56.891  36.055  48.102  1.00 74.53  ? 340  GLN B CD  1 
ATOM   7702  O OE1 . GLN B 2 63  ? 57.552  35.961  49.138  1.00 81.79  ? 340  GLN B OE1 1 
ATOM   7703  N NE2 . GLN B 2 63  ? 56.987  35.178  47.109  1.00 69.76  ? 340  GLN B NE2 1 
ATOM   7704  N N   . LEU B 2 64  ? 55.068  40.498  50.983  1.00 63.67  ? 341  LEU B N   1 
ATOM   7705  C CA  . LEU B 2 64  ? 54.852  41.054  52.316  1.00 71.11  ? 341  LEU B CA  1 
ATOM   7706  C C   . LEU B 2 64  ? 53.630  41.966  52.355  1.00 79.71  ? 341  LEU B C   1 
ATOM   7707  O O   . LEU B 2 64  ? 52.909  42.004  53.359  1.00 74.64  ? 341  LEU B O   1 
ATOM   7708  C CB  . LEU B 2 64  ? 56.099  41.809  52.771  1.00 72.34  ? 341  LEU B CB  1 
ATOM   7709  C CG  . LEU B 2 64  ? 57.310  40.942  53.112  1.00 65.68  ? 341  LEU B CG  1 
ATOM   7710  C CD1 . LEU B 2 64  ? 58.600  41.693  52.825  1.00 68.64  ? 341  LEU B CD1 1 
ATOM   7711  C CD2 . LEU B 2 64  ? 57.257  40.502  54.566  1.00 61.72  ? 341  LEU B CD2 1 
ATOM   7712  N N   . SER B 2 65  ? 53.379  42.705  51.271  1.00 82.00  ? 342  SER B N   1 
ATOM   7713  C CA  . SER B 2 65  ? 52.317  43.705  51.276  1.00 74.23  ? 342  SER B CA  1 
ATOM   7714  C C   . SER B 2 65  ? 50.941  43.077  51.092  1.00 73.47  ? 342  SER B C   1 
ATOM   7715  O O   . SER B 2 65  ? 49.984  43.469  51.770  1.00 88.12  ? 342  SER B O   1 
ATOM   7716  C CB  . SER B 2 65  ? 52.576  44.745  50.185  1.00 83.38  ? 342  SER B CB  1 
ATOM   7717  O OG  . SER B 2 65  ? 52.258  44.231  48.904  1.00 97.68  ? 342  SER B OG  1 
ATOM   7718  N N   . ASP B 2 66  ? 50.819  42.112  50.185  1.00 72.02  ? 343  ASP B N   1 
ATOM   7719  C CA  . ASP B 2 66  ? 49.549  41.460  49.894  1.00 78.85  ? 343  ASP B CA  1 
ATOM   7720  C C   . ASP B 2 66  ? 49.708  39.958  50.064  1.00 86.46  ? 343  ASP B C   1 
ATOM   7721  O O   . ASP B 2 66  ? 50.500  39.328  49.352  1.00 87.48  ? 343  ASP B O   1 
ATOM   7722  C CB  . ASP B 2 66  ? 49.070  41.792  48.479  1.00 87.92  ? 343  ASP B CB  1 
ATOM   7723  C CG  . ASP B 2 66  ? 47.845  40.995  48.079  1.00 90.98  ? 343  ASP B CG  1 
ATOM   7724  O OD1 . ASP B 2 66  ? 46.754  41.268  48.621  1.00 96.59  ? 343  ASP B OD1 1 
ATOM   7725  O OD2 . ASP B 2 66  ? 47.977  40.090  47.228  1.00 90.68  ? 343  ASP B OD2 1 
ATOM   7726  N N   . TYR B 2 67  ? 48.965  39.388  51.011  1.00 79.70  ? 344  TYR B N   1 
ATOM   7727  C CA  . TYR B 2 67  ? 48.867  37.944  51.167  1.00 78.62  ? 344  TYR B CA  1 
ATOM   7728  C C   . TYR B 2 67  ? 47.420  37.486  51.034  1.00 70.76  ? 344  TYR B C   1 
ATOM   7729  O O   . TYR B 2 67  ? 47.021  36.470  51.609  1.00 75.01  ? 344  TYR B O   1 
ATOM   7730  C CB  . TYR B 2 67  ? 49.470  37.486  52.497  1.00 78.25  ? 344  TYR B CB  1 
ATOM   7731  C CG  . TYR B 2 67  ? 48.990  38.231  53.725  1.00 71.87  ? 344  TYR B CG  1 
ATOM   7732  C CD1 . TYR B 2 67  ? 49.627  39.390  54.153  1.00 76.07  ? 344  TYR B CD1 1 
ATOM   7733  C CD2 . TYR B 2 67  ? 47.917  37.761  54.473  1.00 71.22  ? 344  TYR B CD2 1 
ATOM   7734  C CE1 . TYR B 2 67  ? 49.201  40.068  55.281  1.00 87.34  ? 344  TYR B CE1 1 
ATOM   7735  C CE2 . TYR B 2 67  ? 47.483  38.432  55.602  1.00 76.56  ? 344  TYR B CE2 1 
ATOM   7736  C CZ  . TYR B 2 67  ? 48.129  39.585  56.001  1.00 89.66  ? 344  TYR B CZ  1 
ATOM   7737  O OH  . TYR B 2 67  ? 47.701  40.256  57.124  1.00 91.92  ? 344  TYR B OH  1 
ATOM   7738  N N   . SER B 2 68  ? 46.626  38.239  50.267  1.00 72.29  ? 345  SER B N   1 
ATOM   7739  C CA  . SER B 2 68  ? 45.234  37.868  50.044  1.00 73.89  ? 345  SER B CA  1 
ATOM   7740  C C   . SER B 2 68  ? 45.123  36.581  49.240  1.00 73.73  ? 345  SER B C   1 
ATOM   7741  O O   . SER B 2 68  ? 44.197  35.790  49.454  1.00 76.20  ? 345  SER B O   1 
ATOM   7742  C CB  . SER B 2 68  ? 44.498  39.002  49.334  1.00 73.07  ? 345  SER B CB  1 
ATOM   7743  O OG  . SER B 2 68  ? 44.983  39.167  48.012  1.00 63.78  ? 345  SER B OG  1 
ATOM   7744  N N   . ASP B 2 69  ? 46.060  36.346  48.318  1.00 68.56  ? 346  ASP B N   1 
ATOM   7745  C CA  . ASP B 2 69  ? 46.010  35.143  47.495  1.00 58.43  ? 346  ASP B CA  1 
ATOM   7746  C C   . ASP B 2 69  ? 46.232  33.876  48.307  1.00 70.24  ? 346  ASP B C   1 
ATOM   7747  O O   . ASP B 2 69  ? 45.866  32.790  47.848  1.00 81.48  ? 346  ASP B O   1 
ATOM   7748  C CB  . ASP B 2 69  ? 47.052  35.227  46.378  1.00 54.48  ? 346  ASP B CB  1 
ATOM   7749  C CG  . ASP B 2 69  ? 48.323  35.920  46.824  1.00 74.26  ? 346  ASP B CG  1 
ATOM   7750  O OD1 . ASP B 2 69  ? 48.412  36.285  48.013  1.00 86.72  ? 346  ASP B OD1 1 
ATOM   7751  O OD2 . ASP B 2 69  ? 49.234  36.093  45.986  1.00 83.64  ? 346  ASP B OD2 1 
ATOM   7752  N N   . ILE B 2 70  ? 46.815  33.989  49.496  1.00 71.49  ? 347  ILE B N   1 
ATOM   7753  C CA  . ILE B 2 70  ? 47.172  32.835  50.306  1.00 68.03  ? 347  ILE B CA  1 
ATOM   7754  C C   . ILE B 2 70  ? 46.333  32.760  51.583  1.00 70.51  ? 347  ILE B C   1 
ATOM   7755  O O   . ILE B 2 70  ? 46.689  32.049  52.521  1.00 66.46  ? 347  ILE B O   1 
ATOM   7756  C CB  . ILE B 2 70  ? 48.681  32.824  50.598  1.00 60.66  ? 347  ILE B CB  1 
ATOM   7757  C CG1 . ILE B 2 70  ? 49.050  33.892  51.625  1.00 65.43  ? 347  ILE B CG1 1 
ATOM   7758  C CG2 . ILE B 2 70  ? 49.471  33.021  49.314  1.00 57.79  ? 347  ILE B CG2 1 
ATOM   7759  C CD1 . ILE B 2 70  ? 50.525  33.957  51.889  1.00 70.67  ? 347  ILE B CD1 1 
ATOM   7760  N N   . VAL B 2 71  ? 45.209  33.472  51.623  1.00 75.79  ? 348  VAL B N   1 
ATOM   7761  C CA  . VAL B 2 71  ? 44.219  33.319  52.679  1.00 68.99  ? 348  VAL B CA  1 
ATOM   7762  C C   . VAL B 2 71  ? 42.890  32.959  52.031  1.00 78.34  ? 348  VAL B C   1 
ATOM   7763  O O   . VAL B 2 71  ? 42.689  33.137  50.827  1.00 83.01  ? 348  VAL B O   1 
ATOM   7764  C CB  . VAL B 2 71  ? 44.075  34.584  53.550  1.00 63.38  ? 348  VAL B CB  1 
ATOM   7765  C CG1 . VAL B 2 71  ? 45.350  34.836  54.337  1.00 56.36  ? 348  VAL B CG1 1 
ATOM   7766  C CG2 . VAL B 2 71  ? 43.722  35.784  52.689  1.00 79.09  ? 348  VAL B CG2 1 
ATOM   7767  N N   . THR B 2 72  ? 41.976  32.442  52.848  1.00 79.42  ? 349  THR B N   1 
ATOM   7768  C CA  . THR B 2 72  ? 40.676  32.012  52.357  1.00 72.52  ? 349  THR B CA  1 
ATOM   7769  C C   . THR B 2 72  ? 39.631  32.263  53.437  1.00 61.71  ? 349  THR B C   1 
ATOM   7770  O O   . THR B 2 72  ? 39.947  32.699  54.548  1.00 67.02  ? 349  THR B O   1 
ATOM   7771  C CB  . THR B 2 72  ? 40.703  30.538  51.946  1.00 78.53  ? 349  THR B CB  1 
ATOM   7772  O OG1 . THR B 2 72  ? 39.476  30.207  51.287  1.00 110.19 ? 349  THR B OG1 1 
ATOM   7773  C CG2 . THR B 2 72  ? 40.867  29.650  53.172  1.00 69.37  ? 349  THR B CG2 1 
ATOM   7774  N N   . THR B 2 73  ? 38.376  31.985  53.100  1.00 69.43  ? 350  THR B N   1 
ATOM   7775  C CA  . THR B 2 73  ? 37.273  32.126  54.037  1.00 75.62  ? 350  THR B CA  1 
ATOM   7776  C C   . THR B 2 73  ? 37.045  30.822  54.793  1.00 74.53  ? 350  THR B C   1 
ATOM   7777  O O   . THR B 2 73  ? 37.659  29.792  54.513  1.00 78.16  ? 350  THR B O   1 
ATOM   7778  C CB  . THR B 2 73  ? 35.996  32.543  53.307  1.00 82.84  ? 350  THR B CB  1 
ATOM   7779  O OG1 . THR B 2 73  ? 35.761  31.659  52.204  1.00 85.01  ? 350  THR B OG1 1 
ATOM   7780  C CG2 . THR B 2 73  ? 36.116  33.972  52.797  1.00 73.68  ? 350  THR B CG2 1 
ATOM   7781  N N   . LEU B 2 74  ? 36.133  30.875  55.759  1.00 64.48  ? 351  LEU B N   1 
ATOM   7782  C CA  . LEU B 2 74  ? 35.894  29.741  56.641  1.00 64.15  ? 351  LEU B CA  1 
ATOM   7783  C C   . LEU B 2 74  ? 34.905  28.779  55.994  1.00 71.26  ? 351  LEU B C   1 
ATOM   7784  O O   . LEU B 2 74  ? 33.805  29.178  55.599  1.00 84.64  ? 351  LEU B O   1 
ATOM   7785  C CB  . LEU B 2 74  ? 35.354  30.222  57.987  1.00 60.49  ? 351  LEU B CB  1 
ATOM   7786  C CG  . LEU B 2 74  ? 35.705  29.430  59.251  1.00 68.71  ? 351  LEU B CG  1 
ATOM   7787  C CD1 . LEU B 2 74  ? 35.315  30.230  60.489  1.00 62.43  ? 351  LEU B CD1 1 
ATOM   7788  C CD2 . LEU B 2 74  ? 35.090  28.039  59.288  1.00 58.93  ? 351  LEU B CD2 1 
ATOM   7789  N N   . ASP B 2 75  ? 35.297  27.510  55.886  1.00 63.75  ? 352  ASP B N   1 
ATOM   7790  C CA  . ASP B 2 75  ? 34.405  26.465  55.386  1.00 65.01  ? 352  ASP B CA  1 
ATOM   7791  C C   . ASP B 2 75  ? 33.620  25.925  56.574  1.00 72.58  ? 352  ASP B C   1 
ATOM   7792  O O   . ASP B 2 75  ? 34.059  25.015  57.280  1.00 68.39  ? 352  ASP B O   1 
ATOM   7793  C CB  . ASP B 2 75  ? 35.187  25.368  54.675  1.00 73.85  ? 352  ASP B CB  1 
ATOM   7794  C CG  . ASP B 2 75  ? 34.284  24.375  53.969  1.00 79.03  ? 352  ASP B CG  1 
ATOM   7795  O OD1 . ASP B 2 75  ? 33.162  24.764  53.582  1.00 88.03  ? 352  ASP B OD1 1 
ATOM   7796  O OD2 . ASP B 2 75  ? 34.692  23.206  53.802  1.00 95.29  ? 352  ASP B OD2 1 
ATOM   7797  N N   . LEU B 2 76  ? 32.439  26.497  56.791  1.00 72.17  ? 353  LEU B N   1 
ATOM   7798  C CA  . LEU B 2 76  ? 31.633  26.150  57.952  1.00 65.90  ? 353  LEU B CA  1 
ATOM   7799  C C   . LEU B 2 76  ? 31.144  24.709  57.872  1.00 65.49  ? 353  LEU B C   1 
ATOM   7800  O O   . LEU B 2 76  ? 30.709  24.238  56.818  1.00 66.90  ? 353  LEU B O   1 
ATOM   7801  C CB  . LEU B 2 76  ? 30.432  27.091  58.061  1.00 63.71  ? 353  LEU B CB  1 
ATOM   7802  C CG  . LEU B 2 76  ? 30.466  28.257  59.051  1.00 68.08  ? 353  LEU B CG  1 
ATOM   7803  C CD1 . LEU B 2 76  ? 31.759  29.043  58.929  1.00 89.83  ? 353  LEU B CD1 1 
ATOM   7804  C CD2 . LEU B 2 76  ? 29.263  29.166  58.850  1.00 92.00  ? 353  LEU B CD2 1 
ATOM   7805  N N   . ALA B 2 77  ? 31.221  24.008  59.001  1.00 51.06  ? 354  ALA B N   1 
ATOM   7806  C CA  . ALA B 2 77  ? 30.543  22.734  59.146  1.00 61.35  ? 354  ALA B CA  1 
ATOM   7807  C C   . ALA B 2 77  ? 29.031  22.963  59.171  1.00 76.55  ? 354  ALA B C   1 
ATOM   7808  O O   . ALA B 2 77  ? 28.575  24.083  59.414  1.00 78.10  ? 354  ALA B O   1 
ATOM   7809  C CB  . ALA B 2 77  ? 31.009  22.036  60.423  1.00 68.42  ? 354  ALA B CB  1 
ATOM   7810  N N   . PRO B 2 78  ? 28.237  21.924  58.903  1.00 68.89  ? 355  PRO B N   1 
ATOM   7811  C CA  . PRO B 2 78  ? 26.772  22.088  58.812  1.00 59.05  ? 355  PRO B CA  1 
ATOM   7812  C C   . PRO B 2 78  ? 26.207  22.846  60.000  1.00 61.47  ? 355  PRO B C   1 
ATOM   7813  O O   . PRO B 2 78  ? 26.275  22.373  61.146  1.00 59.64  ? 355  PRO B O   1 
ATOM   7814  C CB  . PRO B 2 78  ? 26.271  20.640  58.782  1.00 63.56  ? 355  PRO B CB  1 
ATOM   7815  C CG  . PRO B 2 78  ? 27.342  19.935  58.025  1.00 60.67  ? 355  PRO B CG  1 
ATOM   7816  C CD  . PRO B 2 78  ? 28.647  20.575  58.465  1.00 62.04  ? 355  PRO B CD  1 
ATOM   7817  N N   . PRO B 2 79  ? 25.635  24.033  59.764  1.00 53.65  ? 356  PRO B N   1 
ATOM   7818  C CA  . PRO B 2 79  ? 25.160  24.864  60.879  1.00 63.73  ? 356  PRO B CA  1 
ATOM   7819  C C   . PRO B 2 79  ? 23.814  24.429  61.443  1.00 66.96  ? 356  PRO B C   1 
ATOM   7820  O O   . PRO B 2 79  ? 23.584  24.555  62.650  1.00 70.55  ? 356  PRO B O   1 
ATOM   7821  C CB  . PRO B 2 79  ? 25.083  26.260  60.247  1.00 64.07  ? 356  PRO B CB  1 
ATOM   7822  C CG  . PRO B 2 79  ? 24.753  25.966  58.818  1.00 61.75  ? 356  PRO B CG  1 
ATOM   7823  C CD  . PRO B 2 79  ? 25.601  24.768  58.487  1.00 47.61  ? 356  PRO B CD  1 
ATOM   7824  N N   . THR B 2 80  ? 22.916  23.926  60.602  1.00 67.46  ? 357  THR B N   1 
ATOM   7825  C CA  . THR B 2 80  ? 21.619  23.458  61.066  1.00 61.73  ? 357  THR B CA  1 
ATOM   7826  C C   . THR B 2 80  ? 21.606  21.936  61.134  1.00 58.97  ? 357  THR B C   1 
ATOM   7827  O O   . THR B 2 80  ? 22.339  21.257  60.410  1.00 61.84  ? 357  THR B O   1 
ATOM   7828  C CB  . THR B 2 80  ? 20.489  23.941  60.154  1.00 78.63  ? 357  THR B CB  1 
ATOM   7829  O OG1 . THR B 2 80  ? 20.636  23.355  58.856  1.00 72.13  ? 357  THR B OG1 1 
ATOM   7830  C CG2 . THR B 2 80  ? 20.526  25.455  60.022  1.00 86.18  ? 357  THR B CG2 1 
ATOM   7831  N N   . LYS B 2 81  ? 20.760  21.406  62.021  1.00 56.60  ? 358  LYS B N   1 
ATOM   7832  C CA  . LYS B 2 81  ? 20.612  19.957  62.129  1.00 50.07  ? 358  LYS B CA  1 
ATOM   7833  C C   . LYS B 2 81  ? 20.157  19.348  60.811  1.00 66.61  ? 358  LYS B C   1 
ATOM   7834  O O   . LYS B 2 81  ? 20.560  18.232  60.461  1.00 66.95  ? 358  LYS B O   1 
ATOM   7835  C CB  . LYS B 2 81  ? 19.618  19.603  63.232  1.00 53.48  ? 358  LYS B CB  1 
ATOM   7836  C CG  . LYS B 2 81  ? 19.767  20.381  64.521  1.00 52.59  ? 358  LYS B CG  1 
ATOM   7837  C CD  . LYS B 2 81  ? 19.362  19.500  65.694  1.00 57.06  ? 358  LYS B CD  1 
ATOM   7838  C CE  . LYS B 2 81  ? 19.460  20.239  67.012  1.00 70.82  ? 358  LYS B CE  1 
ATOM   7839  N NZ  . LYS B 2 81  ? 20.068  19.390  68.076  1.00 77.65  ? 358  LYS B NZ  1 
ATOM   7840  N N   . LYS B 2 82  ? 19.303  20.060  60.074  1.00 70.23  ? 359  LYS B N   1 
ATOM   7841  C CA  . LYS B 2 82  ? 18.800  19.525  58.812  1.00 87.40  ? 359  LYS B CA  1 
ATOM   7842  C C   . LYS B 2 82  ? 19.918  19.412  57.784  1.00 75.05  ? 359  LYS B C   1 
ATOM   7843  O O   . LYS B 2 82  ? 19.971  18.441  57.023  1.00 67.77  ? 359  LYS B O   1 
ATOM   7844  C CB  . LYS B 2 82  ? 17.660  20.395  58.267  1.00 92.42  ? 359  LYS B CB  1 
ATOM   7845  C CG  . LYS B 2 82  ? 16.840  21.193  59.298  1.00 107.38 ? 359  LYS B CG  1 
ATOM   7846  C CD  . LYS B 2 82  ? 16.362  20.357  60.492  1.00 107.93 ? 359  LYS B CD  1 
ATOM   7847  C CE  . LYS B 2 82  ? 15.978  21.237  61.680  1.00 103.95 ? 359  LYS B CE  1 
ATOM   7848  N NZ  . LYS B 2 82  ? 15.801  20.465  62.947  1.00 102.56 ? 359  LYS B NZ  1 
ATOM   7849  N N   . LEU B 2 83  ? 20.823  20.395  57.743  1.00 72.99  ? 360  LEU B N   1 
ATOM   7850  C CA  . LEU B 2 83  ? 21.947  20.322  56.812  1.00 73.65  ? 360  LEU B CA  1 
ATOM   7851  C C   . LEU B 2 83  ? 22.873  19.161  57.155  1.00 74.46  ? 360  LEU B C   1 
ATOM   7852  O O   . LEU B 2 83  ? 23.420  18.510  56.261  1.00 76.09  ? 360  LEU B O   1 
ATOM   7853  C CB  . LEU B 2 83  ? 22.711  21.645  56.813  1.00 54.35  ? 360  LEU B CB  1 
ATOM   7854  C CG  . LEU B 2 83  ? 22.047  22.832  56.112  1.00 51.49  ? 360  LEU B CG  1 
ATOM   7855  C CD1 . LEU B 2 83  ? 23.056  23.945  55.885  1.00 59.77  ? 360  LEU B CD1 1 
ATOM   7856  C CD2 . LEU B 2 83  ? 21.416  22.397  54.799  1.00 68.48  ? 360  LEU B CD2 1 
ATOM   7857  N N   . MET B 2 84  ? 23.049  18.882  58.446  1.00 64.47  ? 361  MET B N   1 
ATOM   7858  C CA  . MET B 2 84  ? 23.858  17.747  58.884  1.00 61.23  ? 361  MET B CA  1 
ATOM   7859  C C   . MET B 2 84  ? 23.199  16.427  58.480  1.00 81.80  ? 361  MET B C   1 
ATOM   7860  O O   . MET B 2 84  ? 23.848  15.512  57.937  1.00 80.01  ? 361  MET B O   1 
ATOM   7861  C CB  . MET B 2 84  ? 24.041  17.861  60.401  1.00 53.08  ? 361  MET B CB  1 
ATOM   7862  C CG  . MET B 2 84  ? 24.586  16.680  61.162  1.00 66.97  ? 361  MET B CG  1 
ATOM   7863  S SD  . MET B 2 84  ? 25.506  17.306  62.589  1.00 66.98  ? 361  MET B SD  1 
ATOM   7864  C CE  . MET B 2 84  ? 24.177  17.626  63.753  1.00 39.83  ? 361  MET B CE  1 
ATOM   7865  N N   . MET B 2 85  ? 21.888  16.329  58.715  1.00 79.89  ? 362  MET B N   1 
ATOM   7866  C CA  . MET B 2 85  ? 21.146  15.148  58.301  1.00 82.54  ? 362  MET B CA  1 
ATOM   7867  C C   . MET B 2 85  ? 21.219  14.967  56.791  1.00 77.42  ? 362  MET B C   1 
ATOM   7868  O O   . MET B 2 85  ? 21.245  13.838  56.297  1.00 83.96  ? 362  MET B O   1 
ATOM   7869  C CB  . MET B 2 85  ? 19.691  15.252  58.763  1.00 88.77  ? 362  MET B CB  1 
ATOM   7870  C CG  . MET B 2 85  ? 18.736  14.307  58.038  1.00 91.49  ? 362  MET B CG  1 
ATOM   7871  S SD  . MET B 2 85  ? 18.070  14.884  56.462  1.00 97.65  ? 362  MET B SD  1 
ATOM   7872  C CE  . MET B 2 85  ? 16.554  15.652  57.018  1.00 96.47  ? 362  MET B CE  1 
ATOM   7873  N N   . TRP B 2 86  ? 21.234  16.068  56.036  1.00 76.74  ? 363  TRP B N   1 
ATOM   7874  C CA  . TRP B 2 86  ? 21.349  15.954  54.587  1.00 82.31  ? 363  TRP B CA  1 
ATOM   7875  C C   . TRP B 2 86  ? 22.760  15.565  54.174  1.00 78.25  ? 363  TRP B C   1 
ATOM   7876  O O   . TRP B 2 86  ? 22.941  14.872  53.167  1.00 74.86  ? 363  TRP B O   1 
ATOM   7877  C CB  . TRP B 2 86  ? 20.941  17.261  53.906  1.00 82.08  ? 363  TRP B CB  1 
ATOM   7878  C CG  . TRP B 2 86  ? 19.471  17.353  53.621  1.00 92.16  ? 363  TRP B CG  1 
ATOM   7879  C CD1 . TRP B 2 86  ? 18.692  16.407  53.018  1.00 96.48  ? 363  TRP B CD1 1 
ATOM   7880  C CD2 . TRP B 2 86  ? 18.608  18.460  53.906  1.00 88.15  ? 363  TRP B CD2 1 
ATOM   7881  N NE1 . TRP B 2 86  ? 17.396  16.851  52.925  1.00 85.12  ? 363  TRP B NE1 1 
ATOM   7882  C CE2 . TRP B 2 86  ? 17.318  18.109  53.462  1.00 83.97  ? 363  TRP B CE2 1 
ATOM   7883  C CE3 . TRP B 2 86  ? 18.800  19.712  54.498  1.00 91.31  ? 363  TRP B CE3 1 
ATOM   7884  C CZ2 . TRP B 2 86  ? 16.226  18.963  53.591  1.00 98.62  ? 363  TRP B CZ2 1 
ATOM   7885  C CZ3 . TRP B 2 86  ? 17.714  20.557  54.627  1.00 96.38  ? 363  TRP B CZ3 1 
ATOM   7886  C CH2 . TRP B 2 86  ? 16.445  20.180  54.175  1.00 98.70  ? 363  TRP B CH2 1 
ATOM   7887  N N   . LYS B 2 87  ? 23.767  16.015  54.925  1.00 77.34  ? 364  LYS B N   1 
ATOM   7888  C CA  . LYS B 2 87  ? 25.132  15.560  54.686  1.00 62.61  ? 364  LYS B CA  1 
ATOM   7889  C C   . LYS B 2 87  ? 25.224  14.047  54.778  1.00 76.20  ? 364  LYS B C   1 
ATOM   7890  O O   . LYS B 2 87  ? 25.924  13.411  53.982  1.00 101.57 ? 364  LYS B O   1 
ATOM   7891  C CB  . LYS B 2 87  ? 26.094  16.210  55.679  1.00 70.11  ? 364  LYS B CB  1 
ATOM   7892  C CG  . LYS B 2 87  ? 27.559  16.101  55.279  1.00 90.35  ? 364  LYS B CG  1 
ATOM   7893  C CD  . LYS B 2 87  ? 28.443  16.977  56.152  1.00 98.36  ? 364  LYS B CD  1 
ATOM   7894  C CE  . LYS B 2 87  ? 29.439  17.760  55.313  1.00 96.74  ? 364  LYS B CE  1 
ATOM   7895  N NZ  . LYS B 2 87  ? 28.764  18.527  54.229  1.00 83.58  ? 364  LYS B NZ  1 
ATOM   7896  N N   . GLU B 2 88  ? 24.531  13.446  55.745  1.00 82.09  ? 365  GLU B N   1 
ATOM   7897  C CA  . GLU B 2 88  ? 24.573  11.983  55.797  1.00 74.80  ? 365  GLU B CA  1 
ATOM   7898  C C   . GLU B 2 88  ? 23.617  11.347  54.784  1.00 80.39  ? 365  GLU B C   1 
ATOM   7899  O O   . GLU B 2 88  ? 24.035  10.553  53.934  1.00 86.62  ? 365  GLU B O   1 
ATOM   7900  C CB  . GLU B 2 88  ? 24.289  11.466  57.211  1.00 71.13  ? 365  GLU B CB  1 
ATOM   7901  C CG  . GLU B 2 88  ? 23.189  12.164  57.970  1.00 105.09 ? 365  GLU B CG  1 
ATOM   7902  C CD  . GLU B 2 88  ? 23.081  11.656  59.392  1.00 112.09 ? 365  GLU B CD  1 
ATOM   7903  O OE1 . GLU B 2 88  ? 22.474  10.582  59.592  1.00 126.92 ? 365  GLU B OE1 1 
ATOM   7904  O OE2 . GLU B 2 88  ? 23.609  12.320  60.307  1.00 95.78  ? 365  GLU B OE2 1 
ATOM   7905  N N   . THR B 2 89  ? 22.329  11.699  54.850  1.00 80.64  ? 366  THR B N   1 
ATOM   7906  C CA  . THR B 2 89  ? 21.306  11.024  54.052  1.00 76.43  ? 366  THR B CA  1 
ATOM   7907  C C   . THR B 2 89  ? 21.420  11.371  52.572  1.00 78.80  ? 366  THR B C   1 
ATOM   7908  O O   . THR B 2 89  ? 21.222  10.505  51.711  1.00 79.17  ? 366  THR B O   1 
ATOM   7909  C CB  . THR B 2 89  ? 19.912  11.386  54.567  1.00 90.34  ? 366  THR B CB  1 
ATOM   7910  O OG1 . THR B 2 89  ? 19.723  12.805  54.490  1.00 97.17  ? 366  THR B OG1 1 
ATOM   7911  C CG2 . THR B 2 89  ? 19.740  10.935  56.013  1.00 85.24  ? 366  THR B CG2 1 
ATOM   7912  N N   . GLY B 2 90  ? 21.704  12.631  52.254  1.00 73.75  ? 367  GLY B N   1 
ATOM   7913  C CA  . GLY B 2 90  ? 21.890  13.012  50.871  1.00 67.30  ? 367  GLY B CA  1 
ATOM   7914  C C   . GLY B 2 90  ? 23.130  12.382  50.268  1.00 85.32  ? 367  GLY B C   1 
ATOM   7915  O O   . GLY B 2 90  ? 24.020  11.889  50.961  1.00 97.65  ? 367  GLY B O   1 
ATOM   7916  N N   . GLY B 2 91  ? 23.187  12.404  48.941  1.00 69.73  ? 368  GLY B N   1 
ATOM   7917  C CA  . GLY B 2 91  ? 24.286  11.776  48.240  1.00 76.18  ? 368  GLY B CA  1 
ATOM   7918  C C   . GLY B 2 91  ? 23.878  10.442  47.660  1.00 78.16  ? 368  GLY B C   1 
ATOM   7919  O O   . GLY B 2 91  ? 23.184  9.662   48.321  1.00 75.33  ? 368  GLY B O   1 
ATOM   7920  N N   . VAL B 2 92  ? 24.315  10.169  46.426  1.00 80.50  ? 369  VAL B N   1 
ATOM   7921  C CA  . VAL B 2 92  ? 23.835  9.000   45.690  1.00 77.26  ? 369  VAL B CA  1 
ATOM   7922  C C   . VAL B 2 92  ? 24.047  7.721   46.491  1.00 79.32  ? 369  VAL B C   1 
ATOM   7923  O O   . VAL B 2 92  ? 23.190  6.825   46.491  1.00 79.24  ? 369  VAL B O   1 
ATOM   7924  C CB  . VAL B 2 92  ? 24.511  8.933   44.306  1.00 72.90  ? 369  VAL B CB  1 
ATOM   7925  C CG1 . VAL B 2 92  ? 24.056  10.101  43.444  1.00 81.19  ? 369  VAL B CG1 1 
ATOM   7926  C CG2 . VAL B 2 92  ? 26.025  8.944   44.444  1.00 80.30  ? 369  VAL B CG2 1 
ATOM   7927  N N   . GLU B 2 93  ? 25.165  7.640   47.224  1.00 82.46  ? 370  GLU B N   1 
ATOM   7928  C CA  . GLU B 2 93  ? 25.498  6.429   47.971  1.00 85.04  ? 370  GLU B CA  1 
ATOM   7929  C C   . GLU B 2 93  ? 24.372  6.037   48.914  1.00 81.30  ? 370  GLU B C   1 
ATOM   7930  O O   . GLU B 2 93  ? 24.069  4.849   49.076  1.00 89.88  ? 370  GLU B O   1 
ATOM   7931  C CB  . GLU B 2 93  ? 26.792  6.633   48.766  1.00 86.04  ? 370  GLU B CB  1 
ATOM   7932  C CG  . GLU B 2 93  ? 26.803  7.874   49.660  1.00 93.56  ? 370  GLU B CG  1 
ATOM   7933  C CD  . GLU B 2 93  ? 27.278  9.130   48.954  1.00 109.62 ? 370  GLU B CD  1 
ATOM   7934  O OE1 . GLU B 2 93  ? 27.372  9.122   47.709  1.00 118.80 ? 370  GLU B OE1 1 
ATOM   7935  O OE2 . GLU B 2 93  ? 27.555  10.129  49.652  1.00 110.56 ? 370  GLU B OE2 1 
ATOM   7936  N N   . LYS B 2 94  ? 23.738  7.025   49.542  1.00 73.56  ? 371  LYS B N   1 
ATOM   7937  C CA  . LYS B 2 94  ? 22.640  6.793   50.467  1.00 75.54  ? 371  LYS B CA  1 
ATOM   7938  C C   . LYS B 2 94  ? 21.288  7.001   49.808  1.00 77.00  ? 371  LYS B C   1 
ATOM   7939  O O   . LYS B 2 94  ? 20.344  6.260   50.095  1.00 73.33  ? 371  LYS B O   1 
ATOM   7940  C CB  . LYS B 2 94  ? 22.767  7.730   51.674  1.00 77.54  ? 371  LYS B CB  1 
ATOM   7941  C CG  . LYS B 2 94  ? 24.121  7.667   52.375  1.00 80.18  ? 371  LYS B CG  1 
ATOM   7942  C CD  . LYS B 2 94  ? 24.410  6.345   53.077  1.00 73.86  ? 371  LYS B CD  1 
ATOM   7943  C CE  . LYS B 2 94  ? 23.265  5.891   53.959  1.00 74.67  ? 371  LYS B CE  1 
ATOM   7944  N NZ  . LYS B 2 94  ? 23.253  4.410   54.108  1.00 86.57  ? 371  LYS B NZ  1 
ATOM   7945  N N   . LEU B 2 95  ? 21.186  7.994   48.915  1.00 73.24  ? 372  LEU B N   1 
ATOM   7946  C CA  . LEU B 2 95  ? 19.930  8.269   48.221  1.00 62.17  ? 372  LEU B CA  1 
ATOM   7947  C C   . LEU B 2 95  ? 19.418  7.040   47.483  1.00 63.25  ? 372  LEU B C   1 
ATOM   7948  O O   . LEU B 2 95  ? 18.247  6.668   47.614  1.00 71.91  ? 372  LEU B O   1 
ATOM   7949  C CB  . LEU B 2 95  ? 20.105  9.435   47.244  1.00 52.39  ? 372  LEU B CB  1 
ATOM   7950  C CG  . LEU B 2 95  ? 19.991  10.868  47.763  1.00 54.10  ? 372  LEU B CG  1 
ATOM   7951  C CD1 . LEU B 2 95  ? 19.940  11.837  46.593  1.00 59.24  ? 372  LEU B CD1 1 
ATOM   7952  C CD2 . LEU B 2 95  ? 18.760  11.025  48.637  1.00 62.62  ? 372  LEU B CD2 1 
ATOM   7953  N N   . PHE B 2 96  ? 20.280  6.393   46.695  1.00 68.15  ? 373  PHE B N   1 
ATOM   7954  C CA  . PHE B 2 96  ? 19.812  5.248   45.922  1.00 67.95  ? 373  PHE B CA  1 
ATOM   7955  C C   . PHE B 2 96  ? 19.580  4.010   46.777  1.00 72.80  ? 373  PHE B C   1 
ATOM   7956  O O   . PHE B 2 96  ? 19.069  3.012   46.258  1.00 76.81  ? 373  PHE B O   1 
ATOM   7957  C CB  . PHE B 2 96  ? 20.797  4.932   44.797  1.00 73.13  ? 373  PHE B CB  1 
ATOM   7958  C CG  . PHE B 2 96  ? 20.665  5.840   43.613  1.00 61.86  ? 373  PHE B CG  1 
ATOM   7959  C CD1 . PHE B 2 96  ? 21.160  7.132   43.660  1.00 61.32  ? 373  PHE B CD1 1 
ATOM   7960  C CD2 . PHE B 2 96  ? 20.033  5.410   42.458  1.00 45.23  ? 373  PHE B CD2 1 
ATOM   7961  C CE1 . PHE B 2 96  ? 21.035  7.977   42.577  1.00 67.47  ? 373  PHE B CE1 1 
ATOM   7962  C CE2 . PHE B 2 96  ? 19.905  6.251   41.370  1.00 48.84  ? 373  PHE B CE2 1 
ATOM   7963  C CZ  . PHE B 2 96  ? 20.407  7.536   41.429  1.00 59.31  ? 373  PHE B CZ  1 
ATOM   7964  N N   . PHE B 2 97  ? 19.927  4.050   48.063  1.00 60.19  ? 374  PHE B N   1 
ATOM   7965  C CA  . PHE B 2 97  ? 19.746  2.911   48.948  1.00 65.45  ? 374  PHE B CA  1 
ATOM   7966  C C   . PHE B 2 97  ? 18.776  3.192   50.086  1.00 74.34  ? 374  PHE B C   1 
ATOM   7967  O O   . PHE B 2 97  ? 18.604  2.333   50.959  1.00 75.01  ? 374  PHE B O   1 
ATOM   7968  C CB  . PHE B 2 97  ? 21.100  2.471   49.523  1.00 85.61  ? 374  PHE B CB  1 
ATOM   7969  C CG  . PHE B 2 97  ? 22.024  1.871   48.501  1.00 93.98  ? 374  PHE B CG  1 
ATOM   7970  C CD1 . PHE B 2 97  ? 21.523  1.294   47.346  1.00 87.66  ? 374  PHE B CD1 1 
ATOM   7971  C CD2 . PHE B 2 97  ? 23.395  1.898   48.689  1.00 108.45 ? 374  PHE B CD2 1 
ATOM   7972  C CE1 . PHE B 2 97  ? 22.371  0.750   46.404  1.00 82.63  ? 374  PHE B CE1 1 
ATOM   7973  C CE2 . PHE B 2 97  ? 24.248  1.357   47.750  1.00 113.39 ? 374  PHE B CE2 1 
ATOM   7974  C CZ  . PHE B 2 97  ? 23.736  0.781   46.607  1.00 105.62 ? 374  PHE B CZ  1 
ATOM   7975  N N   . LEU B 2 98  ? 18.138  4.357   50.097  1.00 77.63  ? 375  LEU B N   1 
ATOM   7976  C CA  . LEU B 2 98  ? 17.229  4.781   51.149  1.00 60.78  ? 375  LEU B CA  1 
ATOM   7977  C C   . LEU B 2 98  ? 15.910  5.242   50.545  1.00 69.27  ? 375  LEU B C   1 
ATOM   7978  O O   . LEU B 2 98  ? 15.886  5.788   49.437  1.00 72.05  ? 375  LEU B O   1 
ATOM   7979  C CB  . LEU B 2 98  ? 17.839  5.922   51.978  1.00 56.72  ? 375  LEU B CB  1 
ATOM   7980  C CG  . LEU B 2 98  ? 18.951  5.500   52.936  1.00 46.78  ? 375  LEU B CG  1 
ATOM   7981  C CD1 . LEU B 2 98  ? 19.482  6.699   53.705  1.00 64.63  ? 375  LEU B CD1 1 
ATOM   7982  C CD2 . LEU B 2 98  ? 18.454  4.419   53.881  1.00 48.39  ? 375  LEU B CD2 1 
ATOM   7983  N N   . PRO B 2 99  ? 14.800  5.046   51.254  1.00 75.45  ? 376  PRO B N   1 
ATOM   7984  C CA  . PRO B 2 99  ? 13.494  5.387   50.683  1.00 71.80  ? 376  PRO B CA  1 
ATOM   7985  C C   . PRO B 2 99  ? 13.284  6.889   50.631  1.00 71.91  ? 376  PRO B C   1 
ATOM   7986  O O   . PRO B 2 99  ? 13.888  7.651   51.389  1.00 71.11  ? 376  PRO B O   1 
ATOM   7987  C CB  . PRO B 2 99  ? 12.509  4.725   51.651  1.00 61.38  ? 376  PRO B CB  1 
ATOM   7988  C CG  . PRO B 2 99  ? 13.227  4.771   52.960  1.00 54.22  ? 376  PRO B CG  1 
ATOM   7989  C CD  . PRO B 2 99  ? 14.677  4.526   52.625  1.00 75.73  ? 376  PRO B CD  1 
ATOM   7990  N N   . ALA B 2 100 ? 12.412  7.314   49.716  1.00 70.27  ? 377  ALA B N   1 
ATOM   7991  C CA  . ALA B 2 100 ? 12.074  8.729   49.634  1.00 63.98  ? 377  ALA B CA  1 
ATOM   7992  C C   . ALA B 2 100 ? 11.260  9.168   50.846  1.00 65.63  ? 377  ALA B C   1 
ATOM   7993  O O   . ALA B 2 100 ? 11.421  10.292  51.336  1.00 67.35  ? 377  ALA B O   1 
ATOM   7994  C CB  . ALA B 2 100 ? 11.319  9.014   48.338  1.00 68.43  ? 377  ALA B CB  1 
ATOM   7995  N N   . GLN B 2 101 ? 10.379  8.296   51.341  1.00 64.82  ? 378  GLN B N   1 
ATOM   7996  C CA  . GLN B 2 101 ? 9.642   8.554   52.568  1.00 61.60  ? 378  GLN B CA  1 
ATOM   7997  C C   . GLN B 2 101 ? 10.330  7.833   53.715  1.00 67.56  ? 378  GLN B C   1 
ATOM   7998  O O   . GLN B 2 101 ? 10.303  6.593   53.756  1.00 70.59  ? 378  GLN B O   1 
ATOM   7999  C CB  . GLN B 2 101 ? 8.193   8.092   52.440  1.00 68.21  ? 378  GLN B CB  1 
ATOM   8000  C CG  . GLN B 2 101 ? 7.314   8.449   53.629  1.00 70.28  ? 378  GLN B CG  1 
ATOM   8001  C CD  . GLN B 2 101 ? 7.407   9.914   54.018  1.00 61.30  ? 378  GLN B CD  1 
ATOM   8002  O OE1 . GLN B 2 101 ? 7.447   10.799  53.163  1.00 53.62  ? 378  GLN B OE1 1 
ATOM   8003  N NE2 . GLN B 2 101 ? 7.441   10.175  55.321  1.00 62.31  ? 378  GLN B NE2 1 
ATOM   8004  N N   . PRO B 2 102 ? 10.949  8.546   54.655  1.00 57.16  ? 379  PRO B N   1 
ATOM   8005  C CA  . PRO B 2 102 ? 11.746  7.879   55.693  1.00 45.54  ? 379  PRO B CA  1 
ATOM   8006  C C   . PRO B 2 102 ? 10.917  6.904   56.517  1.00 55.84  ? 379  PRO B C   1 
ATOM   8007  O O   . PRO B 2 102 ? 9.841   7.240   57.017  1.00 62.46  ? 379  PRO B O   1 
ATOM   8008  C CB  . PRO B 2 102 ? 12.257  9.047   56.544  1.00 39.80  ? 379  PRO B CB  1 
ATOM   8009  C CG  . PRO B 2 102 ? 12.309  10.193  55.584  1.00 58.01  ? 379  PRO B CG  1 
ATOM   8010  C CD  . PRO B 2 102 ? 11.103  10.011  54.702  1.00 51.51  ? 379  PRO B CD  1 
ATOM   8011  N N   . LEU B 2 103 ? 11.430  5.683   56.644  1.00 63.27  ? 380  LEU B N   1 
ATOM   8012  C CA  . LEU B 2 103 ? 10.812  4.639   57.450  1.00 67.60  ? 380  LEU B CA  1 
ATOM   8013  C C   . LEU B 2 103 ? 11.631  4.472   58.722  1.00 71.17  ? 380  LEU B C   1 
ATOM   8014  O O   . LEU B 2 103 ? 12.808  4.098   58.664  1.00 77.81  ? 380  LEU B O   1 
ATOM   8015  C CB  . LEU B 2 103 ? 10.733  3.324   56.677  1.00 60.78  ? 380  LEU B CB  1 
ATOM   8016  C CG  . LEU B 2 103 ? 9.992   3.445   55.346  1.00 65.10  ? 380  LEU B CG  1 
ATOM   8017  C CD1 . LEU B 2 103 ? 10.256  2.246   54.440  1.00 82.60  ? 380  LEU B CD1 1 
ATOM   8018  C CD2 . LEU B 2 103 ? 8.507   3.659   55.577  1.00 72.88  ? 380  LEU B CD2 1 
ATOM   8019  N N   . TRP B 2 104 ? 11.008  4.749   59.866  1.00 64.33  ? 381  TRP B N   1 
ATOM   8020  C CA  . TRP B 2 104 ? 11.743  4.844   61.120  1.00 64.66  ? 381  TRP B CA  1 
ATOM   8021  C C   . TRP B 2 104 ? 11.964  3.496   61.790  1.00 69.26  ? 381  TRP B C   1 
ATOM   8022  O O   . TRP B 2 104 ? 12.813  3.400   62.683  1.00 82.10  ? 381  TRP B O   1 
ATOM   8023  C CB  . TRP B 2 104 ? 11.009  5.792   62.067  1.00 66.37  ? 381  TRP B CB  1 
ATOM   8024  C CG  . TRP B 2 104 ? 10.874  7.168   61.501  1.00 69.47  ? 381  TRP B CG  1 
ATOM   8025  C CD1 . TRP B 2 104 ? 11.642  7.732   60.521  1.00 71.53  ? 381  TRP B CD1 1 
ATOM   8026  C CD2 . TRP B 2 104 ? 9.896   8.149   61.856  1.00 62.56  ? 381  TRP B CD2 1 
ATOM   8027  N NE1 . TRP B 2 104 ? 11.212  9.009   60.258  1.00 79.21  ? 381  TRP B NE1 1 
ATOM   8028  C CE2 . TRP B 2 104 ? 10.140  9.289   61.063  1.00 71.97  ? 381  TRP B CE2 1 
ATOM   8029  C CE3 . TRP B 2 104 ? 8.842   8.178   62.773  1.00 58.44  ? 381  TRP B CE3 1 
ATOM   8030  C CZ2 . TRP B 2 104 ? 9.366   10.442  61.158  1.00 75.03  ? 381  TRP B CZ2 1 
ATOM   8031  C CZ3 . TRP B 2 104 ? 8.078   9.323   62.867  1.00 72.42  ? 381  TRP B CZ3 1 
ATOM   8032  C CH2 . TRP B 2 104 ? 8.341   10.439  62.062  1.00 72.12  ? 381  TRP B CH2 1 
ATOM   8033  N N   . ASN B 2 105 ? 11.231  2.463   61.389  1.00 68.30  ? 382  ASN B N   1 
ATOM   8034  C CA  . ASN B 2 105 ? 11.454  1.112   61.882  1.00 71.36  ? 382  ASN B CA  1 
ATOM   8035  C C   . ASN B 2 105 ? 12.222  0.315   60.837  1.00 79.36  ? 382  ASN B C   1 
ATOM   8036  O O   . ASN B 2 105 ? 11.889  0.359   59.648  1.00 85.38  ? 382  ASN B O   1 
ATOM   8037  C CB  . ASN B 2 105 ? 10.132  0.415   62.211  1.00 79.64  ? 382  ASN B CB  1 
ATOM   8038  C CG  . ASN B 2 105 ? 10.302  -0.706  63.215  1.00 79.48  ? 382  ASN B CG  1 
ATOM   8039  O OD1 . ASN B 2 105 ? 10.976  -1.700  62.943  1.00 80.86  ? 382  ASN B OD1 1 
ATOM   8040  N ND2 . ASN B 2 105 ? 9.693   -0.553  64.384  1.00 80.88  ? 382  ASN B ND2 1 
ATOM   8041  N N   . ASN B 2 106 ? 13.250  -0.410  61.286  1.00 85.32  ? 383  ASN B N   1 
ATOM   8042  C CA  . ASN B 2 106 ? 14.072  -1.188  60.367  1.00 98.01  ? 383  ASN B CA  1 
ATOM   8043  C C   . ASN B 2 106 ? 13.274  -2.271  59.657  1.00 90.11  ? 383  ASN B C   1 
ATOM   8044  O O   . ASN B 2 106 ? 13.687  -2.728  58.586  1.00 89.64  ? 383  ASN B O   1 
ATOM   8045  C CB  . ASN B 2 106 ? 15.249  -1.815  61.114  1.00 95.66  ? 383  ASN B CB  1 
ATOM   8046  C CG  . ASN B 2 106 ? 16.483  -0.940  61.092  1.00 97.33  ? 383  ASN B CG  1 
ATOM   8047  O OD1 . ASN B 2 106 ? 16.409  0.252   60.791  1.00 72.29  ? 383  ASN B OD1 1 
ATOM   8048  N ND2 . ASN B 2 106 ? 17.629  -1.528  61.412  1.00 125.26 ? 383  ASN B ND2 1 
ATOM   8049  N N   . ARG B 2 107 ? 12.140  -2.688  60.222  1.00 74.54  ? 384  ARG B N   1 
ATOM   8050  C CA  . ARG B 2 107 ? 11.320  -3.698  59.563  1.00 69.56  ? 384  ARG B CA  1 
ATOM   8051  C C   . ARG B 2 107 ? 10.667  -3.142  58.305  1.00 78.80  ? 384  ARG B C   1 
ATOM   8052  O O   . ARG B 2 107 ? 10.617  -3.820  57.272  1.00 88.34  ? 384  ARG B O   1 
ATOM   8053  C CB  . ARG B 2 107 ? 10.269  -4.222  60.537  1.00 75.53  ? 384  ARG B CB  1 
ATOM   8054  C CG  . ARG B 2 107 ? 10.863  -4.892  61.761  1.00 92.38  ? 384  ARG B CG  1 
ATOM   8055  C CD  . ARG B 2 107 ? 9.794   -5.206  62.787  1.00 96.15  ? 384  ARG B CD  1 
ATOM   8056  N NE  . ARG B 2 107 ? 8.826   -6.173  62.286  1.00 106.95 ? 384  ARG B NE  1 
ATOM   8057  C CZ  . ARG B 2 107 ? 7.744   -6.557  62.949  1.00 111.32 ? 384  ARG B CZ  1 
ATOM   8058  N NH1 . ARG B 2 107 ? 7.467   -6.080  64.151  1.00 106.85 ? 384  ARG B NH1 1 
ATOM   8059  N NH2 . ARG B 2 107 ? 6.918   -7.437  62.390  1.00 116.61 ? 384  ARG B NH2 1 
ATOM   8060  N N   . LEU B 2 108 ? 10.159  -1.910  58.371  1.00 73.42  ? 385  LEU B N   1 
ATOM   8061  C CA  . LEU B 2 108 ? 9.598   -1.281  57.180  1.00 71.00  ? 385  LEU B CA  1 
ATOM   8062  C C   . LEU B 2 108 ? 10.688  -0.969  56.163  1.00 78.06  ? 385  LEU B C   1 
ATOM   8063  O O   . LEU B 2 108 ? 10.495  -1.167  54.957  1.00 85.18  ? 385  LEU B O   1 
ATOM   8064  C CB  . LEU B 2 108 ? 8.842   -0.011  57.571  1.00 79.86  ? 385  LEU B CB  1 
ATOM   8065  C CG  . LEU B 2 108 ? 7.651   -0.191  58.515  1.00 78.19  ? 385  LEU B CG  1 
ATOM   8066  C CD1 . LEU B 2 108 ? 6.780   1.052   58.507  1.00 79.24  ? 385  LEU B CD1 1 
ATOM   8067  C CD2 . LEU B 2 108 ? 6.832   -1.414  58.127  1.00 72.84  ? 385  LEU B CD2 1 
ATOM   8068  N N   . LEU B 2 109 ? 11.841  -0.486  56.635  1.00 81.40  ? 386  LEU B N   1 
ATOM   8069  C CA  . LEU B 2 109 ? 12.959  -0.187  55.744  1.00 72.97  ? 386  LEU B CA  1 
ATOM   8070  C C   . LEU B 2 109 ? 13.457  -1.436  55.030  1.00 71.80  ? 386  LEU B C   1 
ATOM   8071  O O   . LEU B 2 109 ? 13.881  -1.368  53.867  1.00 66.64  ? 386  LEU B O   1 
ATOM   8072  C CB  . LEU B 2 109 ? 14.099  0.451   56.536  1.00 63.94  ? 386  LEU B CB  1 
ATOM   8073  C CG  . LEU B 2 109 ? 15.334  0.811   55.715  1.00 57.08  ? 386  LEU B CG  1 
ATOM   8074  C CD1 . LEU B 2 109 ? 15.113  2.124   55.013  1.00 57.44  ? 386  LEU B CD1 1 
ATOM   8075  C CD2 . LEU B 2 109 ? 16.566  0.870   56.595  1.00 72.36  ? 386  LEU B CD2 1 
ATOM   8076  N N   . LYS B 2 110 ? 13.426  -2.582  55.719  1.00 64.46  ? 387  LYS B N   1 
ATOM   8077  C CA  . LYS B 2 110 ? 13.939  -3.822  55.149  1.00 68.08  ? 387  LYS B CA  1 
ATOM   8078  C C   . LYS B 2 110 ? 13.214  -4.193  53.869  1.00 70.77  ? 387  LYS B C   1 
ATOM   8079  O O   . LYS B 2 110 ? 13.814  -4.794  52.977  1.00 75.05  ? 387  LYS B O   1 
ATOM   8080  C CB  . LYS B 2 110 ? 13.827  -4.956  56.168  1.00 74.19  ? 387  LYS B CB  1 
ATOM   8081  C CG  . LYS B 2 110 ? 14.796  -6.105  55.928  1.00 78.47  ? 387  LYS B CG  1 
ATOM   8082  C CD  . LYS B 2 110 ? 16.174  -5.805  56.495  1.00 101.46 ? 387  LYS B CD  1 
ATOM   8083  C CE  . LYS B 2 110 ? 16.089  -5.354  57.943  1.00 97.87  ? 387  LYS B CE  1 
ATOM   8084  N NZ  . LYS B 2 110 ? 17.370  -4.766  58.415  1.00 90.04  ? 387  LYS B NZ  1 
ATOM   8085  N N   . LEU B 2 111 ? 11.932  -3.842  53.758  1.00 77.87  ? 388  LEU B N   1 
ATOM   8086  C CA  . LEU B 2 111 ? 11.185  -4.120  52.536  1.00 80.25  ? 388  LEU B CA  1 
ATOM   8087  C C   . LEU B 2 111 ? 11.793  -3.367  51.358  1.00 80.42  ? 388  LEU B C   1 
ATOM   8088  O O   . LEU B 2 111 ? 12.135  -3.958  50.320  1.00 97.98  ? 388  LEU B O   1 
ATOM   8089  C CB  . LEU B 2 111 ? 9.722   -3.722  52.743  1.00 80.60  ? 388  LEU B CB  1 
ATOM   8090  C CG  . LEU B 2 111 ? 9.083   -4.262  54.033  1.00 74.48  ? 388  LEU B CG  1 
ATOM   8091  C CD1 . LEU B 2 111 ? 7.681   -3.700  54.250  1.00 73.26  ? 388  LEU B CD1 1 
ATOM   8092  C CD2 . LEU B 2 111 ? 9.074   -5.784  54.094  1.00 61.12  ? 388  LEU B CD2 1 
ATOM   8093  N N   . PHE B 2 112 ? 11.950  -2.051  51.519  1.00 70.70  ? 389  PHE B N   1 
ATOM   8094  C CA  . PHE B 2 112 ? 12.603  -1.226  50.509  1.00 74.24  ? 389  PHE B CA  1 
ATOM   8095  C C   . PHE B 2 112 ? 13.982  -1.772  50.157  1.00 79.79  ? 389  PHE B C   1 
ATOM   8096  O O   . PHE B 2 112 ? 14.333  -1.888  48.978  1.00 80.21  ? 389  PHE B O   1 
ATOM   8097  C CB  . PHE B 2 112 ? 12.712  0.212   51.016  1.00 72.87  ? 389  PHE B CB  1 
ATOM   8098  C CG  . PHE B 2 112 ? 13.074  1.205   49.954  1.00 69.70  ? 389  PHE B CG  1 
ATOM   8099  C CD1 . PHE B 2 112 ? 12.130  1.633   49.037  1.00 79.94  ? 389  PHE B CD1 1 
ATOM   8100  C CD2 . PHE B 2 112 ? 14.363  1.702   49.865  1.00 66.57  ? 389  PHE B CD2 1 
ATOM   8101  C CE1 . PHE B 2 112 ? 12.462  2.547   48.056  1.00 86.31  ? 389  PHE B CE1 1 
ATOM   8102  C CE2 . PHE B 2 112 ? 14.702  2.613   48.883  1.00 66.03  ? 389  PHE B CE2 1 
ATOM   8103  C CZ  . PHE B 2 112 ? 13.750  3.038   47.978  1.00 70.70  ? 389  PHE B CZ  1 
ATOM   8104  N N   . THR B 2 113 ? 14.777  -2.125  51.173  1.00 82.52  ? 390  THR B N   1 
ATOM   8105  C CA  . THR B 2 113 ? 16.151  -2.549  50.909  1.00 77.56  ? 390  THR B CA  1 
ATOM   8106  C C   . THR B 2 113 ? 16.202  -3.892  50.188  1.00 80.20  ? 390  THR B C   1 
ATOM   8107  O O   . THR B 2 113 ? 16.991  -4.062  49.251  1.00 87.23  ? 390  THR B O   1 
ATOM   8108  C CB  . THR B 2 113 ? 16.961  -2.613  52.206  1.00 69.26  ? 390  THR B CB  1 
ATOM   8109  O OG1 . THR B 2 113 ? 16.473  -3.680  53.029  1.00 82.53  ? 390  THR B OG1 1 
ATOM   8110  C CG2 . THR B 2 113 ? 16.878  -1.294  52.964  1.00 55.35  ? 390  THR B CG2 1 
ATOM   8111  N N   . ARG B 2 114 ? 15.382  -4.862  50.609  1.00 75.84  ? 391  ARG B N   1 
ATOM   8112  C CA  . ARG B 2 114 ? 15.392  -6.161  49.949  1.00 82.38  ? 391  ARG B CA  1 
ATOM   8113  C C   . ARG B 2 114 ? 14.913  -6.045  48.513  1.00 84.37  ? 391  ARG B C   1 
ATOM   8114  O O   . ARG B 2 114 ? 15.364  -6.807  47.651  1.00 80.25  ? 391  ARG B O   1 
ATOM   8115  C CB  . ARG B 2 114 ? 14.527  -7.176  50.704  1.00 80.47  ? 391  ARG B CB  1 
ATOM   8116  C CG  . ARG B 2 114 ? 13.073  -6.773  50.852  1.00 77.11  ? 391  ARG B CG  1 
ATOM   8117  C CD  . ARG B 2 114 ? 12.117  -7.949  50.788  1.00 97.20  ? 391  ARG B CD  1 
ATOM   8118  N NE  . ARG B 2 114 ? 10.727  -7.505  50.769  1.00 97.22  ? 391  ARG B NE  1 
ATOM   8119  C CZ  . ARG B 2 114 ? 9.769   -8.004  51.538  1.00 88.94  ? 391  ARG B CZ  1 
ATOM   8120  N NH1 . ARG B 2 114 ? 10.018  -8.949  52.429  1.00 89.77  ? 391  ARG B NH1 1 
ATOM   8121  N NH2 . ARG B 2 114 ? 8.529   -7.539  51.411  1.00 89.24  ? 391  ARG B NH2 1 
ATOM   8122  N N   . CYS B 2 115 ? 14.002  -5.107  48.229  1.00 94.55  ? 392  CYS B N   1 
ATOM   8123  C CA  . CYS B 2 115 ? 13.654  -4.889  46.829  1.00 96.18  ? 392  CYS B CA  1 
ATOM   8124  C C   . CYS B 2 115 ? 14.786  -4.244  46.039  1.00 106.75 ? 392  CYS B C   1 
ATOM   8125  O O   . CYS B 2 115 ? 14.833  -4.408  44.816  1.00 108.12 ? 392  CYS B O   1 
ATOM   8126  C CB  . CYS B 2 115 ? 12.385  -4.042  46.719  1.00 81.92  ? 392  CYS B CB  1 
ATOM   8127  S SG  . CYS B 2 115 ? 10.910  -4.885  47.323  1.00 117.53 ? 392  CYS B SG  1 
ATOM   8128  N N   . LEU B 2 116 ? 15.705  -3.546  46.701  1.00 115.10 ? 393  LEU B N   1 
ATOM   8129  C CA  . LEU B 2 116 ? 16.826  -2.931  46.000  1.00 109.05 ? 393  LEU B CA  1 
ATOM   8130  C C   . LEU B 2 116 ? 17.796  -3.996  45.500  1.00 117.58 ? 393  LEU B C   1 
ATOM   8131  O O   . LEU B 2 116 ? 18.128  -4.941  46.221  1.00 129.46 ? 393  LEU B O   1 
ATOM   8132  C CB  . LEU B 2 116 ? 17.558  -1.952  46.919  1.00 84.61  ? 393  LEU B CB  1 
ATOM   8133  C CG  . LEU B 2 116 ? 16.778  -0.713  47.359  1.00 83.53  ? 393  LEU B CG  1 
ATOM   8134  C CD1 . LEU B 2 116 ? 17.583  0.097   48.356  1.00 74.39  ? 393  LEU B CD1 1 
ATOM   8135  C CD2 . LEU B 2 116 ? 16.399  0.138   46.160  1.00 84.07  ? 393  LEU B CD2 1 
ATOM   8136  N N   . THR B 2 117 ? 18.257  -3.830  44.261  1.00 119.25 ? 394  THR B N   1 
ATOM   8137  C CA  . THR B 2 117 ? 19.133  -4.799  43.597  1.00 120.23 ? 394  THR B CA  1 
ATOM   8138  C C   . THR B 2 117 ? 18.536  -6.202  43.614  1.00 110.58 ? 394  THR B C   1 
ATOM   8139  O O   . THR B 2 117 ? 17.446  -6.427  43.092  1.00 119.95 ? 394  THR B O   1 
ATOM   8140  C CB  . THR B 2 117 ? 20.535  -4.853  44.238  1.00 145.61 ? 394  THR B CB  1 
ATOM   8141  O OG1 . THR B 2 117 ? 21.055  -3.527  44.381  1.00 161.33 ? 394  THR B OG1 1 
ATOM   8142  C CG2 . THR B 2 117 ? 21.482  -5.672  43.371  1.00 138.19 ? 394  THR B CG2 1 
ATOM   8143  N N   . ASP C 3 8   ? 62.707  47.653  63.039  1.00 92.38  ? 224  ASP C N   1 
ATOM   8144  C CA  . ASP C 3 8   ? 63.646  48.157  62.044  1.00 98.90  ? 224  ASP C CA  1 
ATOM   8145  C C   . ASP C 3 8   ? 64.340  47.005  61.329  1.00 91.21  ? 224  ASP C C   1 
ATOM   8146  O O   . ASP C 3 8   ? 64.416  46.978  60.101  1.00 92.72  ? 224  ASP C O   1 
ATOM   8147  C CB  . ASP C 3 8   ? 64.682  49.075  62.696  1.00 115.76 ? 224  ASP C CB  1 
ATOM   8148  C CG  . ASP C 3 8   ? 65.326  50.025  61.704  1.00 112.60 ? 224  ASP C CG  1 
ATOM   8149  O OD1 . ASP C 3 8   ? 64.702  50.307  60.660  1.00 112.95 ? 224  ASP C OD1 1 
ATOM   8150  O OD2 . ASP C 3 8   ? 66.458  50.484  61.965  1.00 94.61  ? 224  ASP C OD2 1 
ATOM   8151  N N   . GLU C 3 9   ? 64.847  46.055  62.119  1.00 92.81  ? 225  GLU C N   1 
ATOM   8152  C CA  . GLU C 3 9   ? 65.507  44.884  61.553  1.00 81.52  ? 225  GLU C CA  1 
ATOM   8153  C C   . GLU C 3 9   ? 64.559  44.076  60.677  1.00 84.30  ? 225  GLU C C   1 
ATOM   8154  O O   . GLU C 3 9   ? 64.988  43.466  59.690  1.00 80.72  ? 225  GLU C O   1 
ATOM   8155  C CB  . GLU C 3 9   ? 66.066  44.013  62.680  1.00 67.25  ? 225  GLU C CB  1 
ATOM   8156  C CG  . GLU C 3 9   ? 66.980  42.885  62.226  1.00 81.78  ? 225  GLU C CG  1 
ATOM   8157  C CD  . GLU C 3 9   ? 68.396  43.352  61.956  1.00 78.61  ? 225  GLU C CD  1 
ATOM   8158  O OE1 . GLU C 3 9   ? 69.027  43.885  62.892  1.00 82.98  ? 225  GLU C OE1 1 
ATOM   8159  O OE2 . GLU C 3 9   ? 68.881  43.181  60.816  1.00 66.39  ? 225  GLU C OE2 1 
ATOM   8160  N N   . TYR C 3 10  ? 63.270  44.065  61.019  1.00 80.14  ? 226  TYR C N   1 
ATOM   8161  C CA  . TYR C 3 10  ? 62.275  43.305  60.274  1.00 72.98  ? 226  TYR C CA  1 
ATOM   8162  C C   . TYR C 3 10  ? 61.784  44.024  59.025  1.00 69.99  ? 226  TYR C C   1 
ATOM   8163  O O   . TYR C 3 10  ? 61.013  43.439  58.257  1.00 82.39  ? 226  TYR C O   1 
ATOM   8164  C CB  . TYR C 3 10  ? 61.094  42.976  61.187  1.00 65.54  ? 226  TYR C CB  1 
ATOM   8165  C CG  . TYR C 3 10  ? 61.476  42.079  62.338  1.00 63.08  ? 226  TYR C CG  1 
ATOM   8166  C CD1 . TYR C 3 10  ? 62.012  40.820  62.113  1.00 63.45  ? 226  TYR C CD1 1 
ATOM   8167  C CD2 . TYR C 3 10  ? 61.335  42.506  63.651  1.00 59.46  ? 226  TYR C CD2 1 
ATOM   8168  C CE1 . TYR C 3 10  ? 62.372  39.996  63.161  1.00 57.72  ? 226  TYR C CE1 1 
ATOM   8169  C CE2 . TYR C 3 10  ? 61.695  41.691  64.707  1.00 72.87  ? 226  TYR C CE2 1 
ATOM   8170  C CZ  . TYR C 3 10  ? 62.213  40.438  64.457  1.00 69.85  ? 226  TYR C CZ  1 
ATOM   8171  O OH  . TYR C 3 10  ? 62.572  39.623  65.504  1.00 87.14  ? 226  TYR C OH  1 
ATOM   8172  N N   . GLU C 3 11  ? 62.207  45.265  58.802  1.00 73.22  ? 227  GLU C N   1 
ATOM   8173  C CA  . GLU C 3 11  ? 61.854  45.984  57.586  1.00 89.77  ? 227  GLU C CA  1 
ATOM   8174  C C   . GLU C 3 11  ? 62.795  45.569  56.459  1.00 72.26  ? 227  GLU C C   1 
ATOM   8175  O O   . GLU C 3 11  ? 64.019  45.661  56.590  1.00 80.24  ? 227  GLU C O   1 
ATOM   8176  C CB  . GLU C 3 11  ? 61.914  47.491  57.833  1.00 115.78 ? 227  GLU C CB  1 
ATOM   8177  C CG  . GLU C 3 11  ? 61.114  47.922  59.061  1.00 126.00 ? 227  GLU C CG  1 
ATOM   8178  C CD  . GLU C 3 11  ? 61.159  49.417  59.313  1.00 141.12 ? 227  GLU C CD  1 
ATOM   8179  O OE1 . GLU C 3 11  ? 61.409  50.178  58.355  1.00 148.53 ? 227  GLU C OE1 1 
ATOM   8180  O OE2 . GLU C 3 11  ? 60.936  49.830  60.471  1.00 135.84 ? 227  GLU C OE2 1 
ATOM   8181  N N   . PHE C 3 12  ? 62.217  45.109  55.353  1.00 66.40  ? 228  PHE C N   1 
ATOM   8182  C CA  . PHE C 3 12  ? 62.963  44.379  54.333  1.00 63.90  ? 228  PHE C CA  1 
ATOM   8183  C C   . PHE C 3 12  ? 63.681  45.354  53.404  1.00 84.69  ? 228  PHE C C   1 
ATOM   8184  O O   . PHE C 3 12  ? 63.043  46.204  52.774  1.00 103.01 ? 228  PHE C O   1 
ATOM   8185  C CB  . PHE C 3 12  ? 62.011  43.480  53.549  1.00 69.43  ? 228  PHE C CB  1 
ATOM   8186  C CG  . PHE C 3 12  ? 62.649  42.792  52.384  1.00 68.82  ? 228  PHE C CG  1 
ATOM   8187  C CD1 . PHE C 3 12  ? 63.518  41.736  52.586  1.00 78.07  ? 228  PHE C CD1 1 
ATOM   8188  C CD2 . PHE C 3 12  ? 62.386  43.200  51.089  1.00 74.66  ? 228  PHE C CD2 1 
ATOM   8189  C CE1 . PHE C 3 12  ? 64.110  41.096  51.518  1.00 85.00  ? 228  PHE C CE1 1 
ATOM   8190  C CE2 . PHE C 3 12  ? 62.978  42.564  50.016  1.00 75.67  ? 228  PHE C CE2 1 
ATOM   8191  C CZ  . PHE C 3 12  ? 63.841  41.511  50.231  1.00 68.24  ? 228  PHE C CZ  1 
ATOM   8192  N N   . ASP C 3 13  ? 65.009  45.223  53.307  1.00 85.07  ? 229  ASP C N   1 
ATOM   8193  C CA  . ASP C 3 13  ? 65.818  46.110  52.480  1.00 79.72  ? 229  ASP C CA  1 
ATOM   8194  C C   . ASP C 3 13  ? 66.854  45.369  51.643  1.00 86.30  ? 229  ASP C C   1 
ATOM   8195  O O   . ASP C 3 13  ? 67.762  46.009  51.097  1.00 112.33 ? 229  ASP C O   1 
ATOM   8196  C CB  . ASP C 3 13  ? 66.521  47.161  53.349  1.00 89.03  ? 229  ASP C CB  1 
ATOM   8197  C CG  . ASP C 3 13  ? 67.308  46.543  54.492  1.00 109.07 ? 229  ASP C CG  1 
ATOM   8198  O OD1 . ASP C 3 13  ? 66.884  45.486  55.007  1.00 123.56 ? 229  ASP C OD1 1 
ATOM   8199  O OD2 . ASP C 3 13  ? 68.352  47.111  54.873  1.00 125.40 ? 229  ASP C OD2 1 
ATOM   8200  N N   . GLU C 3 14  ? 66.746  44.049  51.520  1.00 87.13  ? 230  GLU C N   1 
ATOM   8201  C CA  . GLU C 3 14  ? 67.743  43.270  50.797  1.00 86.92  ? 230  GLU C CA  1 
ATOM   8202  C C   . GLU C 3 14  ? 67.579  43.435  49.289  1.00 97.78  ? 230  GLU C C   1 
ATOM   8203  O O   . GLU C 3 14  ? 66.472  43.621  48.777  1.00 105.54 ? 230  GLU C O   1 
ATOM   8204  C CB  . GLU C 3 14  ? 67.631  41.789  51.168  1.00 84.81  ? 230  GLU C CB  1 
ATOM   8205  C CG  . GLU C 3 14  ? 67.539  41.515  52.662  1.00 70.92  ? 230  GLU C CG  1 
ATOM   8206  C CD  . GLU C 3 14  ? 68.263  40.245  53.066  1.00 78.87  ? 230  GLU C CD  1 
ATOM   8207  O OE1 . GLU C 3 14  ? 68.320  39.305  52.243  1.00 81.82  ? 230  GLU C OE1 1 
ATOM   8208  O OE2 . GLU C 3 14  ? 68.769  40.184  54.207  1.00 62.98  ? 230  GLU C OE2 1 
ATOM   8209  N N   . ASP C 3 15  ? 68.702  43.361  48.575  1.00 89.49  ? 231  ASP C N   1 
ATOM   8210  C CA  . ASP C 3 15  ? 68.690  43.384  47.120  1.00 102.28 ? 231  ASP C CA  1 
ATOM   8211  C C   . ASP C 3 15  ? 69.860  42.561  46.606  1.00 110.54 ? 231  ASP C C   1 
ATOM   8212  O O   . ASP C 3 15  ? 70.946  42.580  47.194  1.00 103.48 ? 231  ASP C O   1 
ATOM   8213  C CB  . ASP C 3 15  ? 68.770  44.812  46.567  1.00 136.94 ? 231  ASP C CB  1 
ATOM   8214  C CG  . ASP C 3 15  ? 69.000  44.844  45.068  1.00 149.10 ? 231  ASP C CG  1 
ATOM   8215  O OD1 . ASP C 3 15  ? 68.183  44.250  44.330  1.00 140.92 ? 231  ASP C OD1 1 
ATOM   8216  O OD2 . ASP C 3 15  ? 69.998  45.454  44.628  1.00 154.89 ? 231  ASP C OD2 1 
ATOM   8217  N N   . ASP C 3 16  ? 69.635  41.847  45.505  1.00 117.19 ? 232  ASP C N   1 
ATOM   8218  C CA  . ASP C 3 16  ? 70.638  40.947  44.948  1.00 121.13 ? 232  ASP C CA  1 
ATOM   8219  C C   . ASP C 3 16  ? 70.698  41.145  43.436  1.00 105.99 ? 232  ASP C C   1 
ATOM   8220  O O   . ASP C 3 16  ? 70.059  42.043  42.878  1.00 114.90 ? 232  ASP C O   1 
ATOM   8221  C CB  . ASP C 3 16  ? 70.327  39.493  45.318  1.00 112.34 ? 232  ASP C CB  1 
ATOM   8222  C CG  . ASP C 3 16  ? 70.855  39.113  46.681  1.00 110.65 ? 232  ASP C CG  1 
ATOM   8223  O OD1 . ASP C 3 16  ? 72.065  39.301  46.925  1.00 88.03  ? 232  ASP C OD1 1 
ATOM   8224  O OD2 . ASP C 3 16  ? 70.063  38.618  47.508  1.00 121.38 ? 232  ASP C OD2 1 
ATOM   8225  N N   . GLU C 3 17  ? 71.472  40.283  42.777  1.00 98.23  ? 233  GLU C N   1 
ATOM   8226  C CA  . GLU C 3 17  ? 71.802  40.350  41.356  1.00 106.57 ? 233  GLU C CA  1 
ATOM   8227  C C   . GLU C 3 17  ? 72.545  41.629  40.987  1.00 112.53 ? 233  GLU C C   1 
ATOM   8228  O O   . GLU C 3 17  ? 72.781  41.887  39.800  1.00 98.03  ? 233  GLU C O   1 
ATOM   8229  C CB  . GLU C 3 17  ? 70.561  40.184  40.471  1.00 127.77 ? 233  GLU C CB  1 
ATOM   8230  C CG  . GLU C 3 17  ? 69.781  38.905  40.746  1.00 128.88 ? 233  GLU C CG  1 
ATOM   8231  C CD  . GLU C 3 17  ? 70.686  37.731  41.081  1.00 122.58 ? 233  GLU C CD  1 
ATOM   8232  O OE1 . GLU C 3 17  ? 71.296  37.157  40.155  1.00 112.21 ? 233  GLU C OE1 1 
ATOM   8233  O OE2 . GLU C 3 17  ? 70.781  37.379  42.276  1.00 129.16 ? 233  GLU C OE2 1 
ATOM   8234  N N   . GLN C 3 18  ? 72.915  42.439  41.980  1.00 112.84 ? 234  GLN C N   1 
ATOM   8235  C CA  . GLN C 3 18  ? 73.825  43.565  41.809  1.00 102.36 ? 234  GLN C CA  1 
ATOM   8236  C C   . GLN C 3 18  ? 75.022  43.448  42.745  1.00 113.88 ? 234  GLN C C   1 
ATOM   8237  O O   . GLN C 3 18  ? 75.677  44.452  43.044  1.00 122.44 ? 234  GLN C O   1 
ATOM   8238  C CB  . GLN C 3 18  ? 73.093  44.890  42.031  1.00 95.21  ? 234  GLN C CB  1 
ATOM   8239  C CG  . GLN C 3 18  ? 72.290  45.355  40.829  1.00 119.54 ? 234  GLN C CG  1 
ATOM   8240  C CD  . GLN C 3 18  ? 70.975  44.621  40.686  1.00 143.39 ? 234  GLN C CD  1 
ATOM   8241  O OE1 . GLN C 3 18  ? 70.656  44.101  39.616  1.00 131.13 ? 234  GLN C OE1 1 
ATOM   8242  N NE2 . GLN C 3 18  ? 70.209  44.561  41.769  1.00 178.71 ? 234  GLN C NE2 1 
ATOM   8243  N N   . ASP C 3 19  ? 75.312  42.237  43.211  1.00 118.60 ? 235  ASP C N   1 
ATOM   8244  C CA  . ASP C 3 19  ? 76.408  42.000  44.136  1.00 119.52 ? 235  ASP C CA  1 
ATOM   8245  C C   . ASP C 3 19  ? 77.733  41.947  43.388  1.00 123.25 ? 235  ASP C C   1 
ATOM   8246  O O   . ASP C 3 19  ? 77.809  41.473  42.250  1.00 116.39 ? 235  ASP C O   1 
ATOM   8247  C CB  . ASP C 3 19  ? 76.190  40.687  44.889  1.00 123.31 ? 235  ASP C CB  1 
ATOM   8248  C CG  . ASP C 3 19  ? 74.778  40.549  45.420  1.00 117.12 ? 235  ASP C CG  1 
ATOM   8249  O OD1 . ASP C 3 19  ? 74.146  39.507  45.146  1.00 103.89 ? 235  ASP C OD1 1 
ATOM   8250  O OD2 . ASP C 3 19  ? 74.302  41.476  46.106  1.00 116.89 ? 235  ASP C OD2 1 
ATOM   8251  N N   . ARG C 3 20  ? 78.786  42.429  44.042  1.00 124.35 ? 236  ARG C N   1 
ATOM   8252  C CA  . ARG C 3 20  ? 80.108  42.426  43.432  1.00 128.80 ? 236  ARG C CA  1 
ATOM   8253  C C   . ARG C 3 20  ? 80.713  41.030  43.536  1.00 124.14 ? 236  ARG C C   1 
ATOM   8254  O O   . ARG C 3 20  ? 80.714  40.421  44.610  1.00 119.36 ? 236  ARG C O   1 
ATOM   8255  C CB  . ARG C 3 20  ? 81.007  43.468  44.099  1.00 148.78 ? 236  ARG C CB  1 
ATOM   8256  C CG  . ARG C 3 20  ? 82.088  44.031  43.182  1.00 174.45 ? 236  ARG C CG  1 
ATOM   8257  C CD  . ARG C 3 20  ? 83.333  43.161  43.133  1.00 189.65 ? 236  ARG C CD  1 
ATOM   8258  N NE  . ARG C 3 20  ? 83.781  42.764  44.462  1.00 213.47 ? 236  ARG C NE  1 
ATOM   8259  C CZ  . ARG C 3 20  ? 84.999  42.318  44.736  1.00 216.23 ? 236  ARG C CZ  1 
ATOM   8260  N NH1 . ARG C 3 20  ? 85.914  42.185  43.790  1.00 235.11 ? 236  ARG C NH1 1 
ATOM   8261  N NH2 . ARG C 3 20  ? 85.310  42.004  45.991  1.00 202.31 ? 236  ARG C NH2 1 
ATOM   8262  N N   . VAL C 3 21  ? 81.215  40.528  42.415  1.00 121.98 ? 237  VAL C N   1 
ATOM   8263  C CA  . VAL C 3 21  ? 81.729  39.154  42.359  1.00 135.39 ? 237  VAL C CA  1 
ATOM   8264  C C   . VAL C 3 21  ? 82.976  39.044  43.228  1.00 146.84 ? 237  VAL C C   1 
ATOM   8265  O O   . VAL C 3 21  ? 83.760  40.007  43.305  1.00 160.26 ? 237  VAL C O   1 
ATOM   8266  C CB  . VAL C 3 21  ? 82.030  38.761  40.911  1.00 133.81 ? 237  VAL C CB  1 
ATOM   8267  C CG1 . VAL C 3 21  ? 80.740  38.481  40.161  1.00 115.14 ? 237  VAL C CG1 1 
ATOM   8268  C CG2 . VAL C 3 21  ? 82.826  39.858  40.219  1.00 134.32 ? 237  VAL C CG2 1 
ATOM   8269  N N   . PRO C 3 22  ? 83.206  37.910  43.894  1.00 131.38 ? 238  PRO C N   1 
ATOM   8270  C CA  . PRO C 3 22  ? 84.397  37.784  44.726  1.00 124.57 ? 238  PRO C CA  1 
ATOM   8271  C C   . PRO C 3 22  ? 85.652  37.779  43.872  1.00 132.48 ? 238  PRO C C   1 
ATOM   8272  O O   . PRO C 3 22  ? 85.632  37.318  42.718  1.00 129.24 ? 238  PRO C O   1 
ATOM   8273  C CB  . PRO C 3 22  ? 84.192  36.433  45.431  1.00 101.06 ? 238  PRO C CB  1 
ATOM   8274  C CG  . PRO C 3 22  ? 83.346  35.665  44.469  1.00 104.73 ? 238  PRO C CG  1 
ATOM   8275  C CD  . PRO C 3 22  ? 82.387  36.685  43.921  1.00 117.63 ? 238  PRO C CD  1 
ATOM   8276  N N   . PRO C 3 23  ? 86.768  38.290  44.393  1.00 136.83 ? 239  PRO C N   1 
ATOM   8277  C CA  . PRO C 3 23  ? 88.006  38.328  43.602  1.00 120.25 ? 239  PRO C CA  1 
ATOM   8278  C C   . PRO C 3 23  ? 88.526  36.936  43.279  1.00 111.14 ? 239  PRO C C   1 
ATOM   8279  O O   . PRO C 3 23  ? 88.633  36.564  42.106  1.00 105.20 ? 239  PRO C O   1 
ATOM   8280  C CB  . PRO C 3 23  ? 88.987  39.096  44.500  1.00 123.45 ? 239  PRO C CB  1 
ATOM   8281  C CG  . PRO C 3 23  ? 88.161  39.727  45.574  1.00 139.89 ? 239  PRO C CG  1 
ATOM   8282  C CD  . PRO C 3 23  ? 86.913  38.925  45.714  1.00 136.74 ? 239  PRO C CD  1 
ATOM   8283  N N   . VAL C 3 24  ? 88.851  36.160  44.307  1.00 109.59 ? 240  VAL C N   1 
ATOM   8284  C CA  . VAL C 3 24  ? 89.320  34.789  44.144  1.00 101.70 ? 240  VAL C CA  1 
ATOM   8285  C C   . VAL C 3 24  ? 88.237  33.877  44.705  1.00 96.84  ? 240  VAL C C   1 
ATOM   8286  O O   . VAL C 3 24  ? 88.081  33.754  45.925  1.00 91.10  ? 240  VAL C O   1 
ATOM   8287  C CB  . VAL C 3 24  ? 90.667  34.550  44.835  1.00 104.20 ? 240  VAL C CB  1 
ATOM   8288  C CG1 . VAL C 3 24  ? 91.123  33.114  44.616  1.00 73.39  ? 240  VAL C CG1 1 
ATOM   8289  C CG2 . VAL C 3 24  ? 91.711  35.527  44.317  1.00 98.17  ? 240  VAL C CG2 1 
ATOM   8290  N N   . ASP C 3 25  ? 87.482  33.235  43.810  1.00 106.29 ? 241  ASP C N   1 
ATOM   8291  C CA  . ASP C 3 25  ? 86.456  32.290  44.237  1.00 99.12  ? 241  ASP C CA  1 
ATOM   8292  C C   . ASP C 3 25  ? 87.055  31.074  44.932  1.00 97.05  ? 241  ASP C C   1 
ATOM   8293  O O   . ASP C 3 25  ? 86.361  30.412  45.711  1.00 103.46 ? 241  ASP C O   1 
ATOM   8294  C CB  . ASP C 3 25  ? 85.625  31.841  43.030  1.00 88.99  ? 241  ASP C CB  1 
ATOM   8295  C CG  . ASP C 3 25  ? 84.217  31.425  43.410  1.00 133.71 ? 241  ASP C CG  1 
ATOM   8296  O OD1 . ASP C 3 25  ? 84.054  30.327  43.981  1.00 147.84 ? 241  ASP C OD1 1 
ATOM   8297  O OD2 . ASP C 3 25  ? 83.271  32.184  43.112  1.00 153.26 ? 241  ASP C OD2 1 
ATOM   8298  N N   . ASP C 3 26  ? 88.329  30.768  44.672  1.00 90.16  ? 242  ASP C N   1 
ATOM   8299  C CA  . ASP C 3 26  ? 88.938  29.568  45.235  1.00 83.87  ? 242  ASP C CA  1 
ATOM   8300  C C   . ASP C 3 26  ? 89.185  29.708  46.732  1.00 88.68  ? 242  ASP C C   1 
ATOM   8301  O O   . ASP C 3 26  ? 89.168  28.706  47.457  1.00 86.69  ? 242  ASP C O   1 
ATOM   8302  C CB  . ASP C 3 26  ? 90.245  29.253  44.506  1.00 90.19  ? 242  ASP C CB  1 
ATOM   8303  C CG  . ASP C 3 26  ? 90.027  28.463  43.227  1.00 102.12 ? 242  ASP C CG  1 
ATOM   8304  O OD1 . ASP C 3 26  ? 88.882  28.434  42.729  1.00 119.54 ? 242  ASP C OD1 1 
ATOM   8305  O OD2 . ASP C 3 26  ? 91.003  27.874  42.717  1.00 104.09 ? 242  ASP C OD2 1 
ATOM   8306  N N   . LYS C 3 27  ? 89.427  30.926  47.209  1.00 88.25  ? 243  LYS C N   1 
ATOM   8307  C CA  . LYS C 3 27  ? 89.634  31.208  48.630  1.00 86.84  ? 243  LYS C CA  1 
ATOM   8308  C C   . LYS C 3 27  ? 88.600  32.240  49.073  1.00 85.68  ? 243  LYS C C   1 
ATOM   8309  O O   . LYS C 3 27  ? 88.824  33.446  48.947  1.00 91.84  ? 243  LYS C O   1 
ATOM   8310  C CB  . LYS C 3 27  ? 91.054  31.706  48.899  1.00 103.33 ? 243  LYS C CB  1 
ATOM   8311  C CG  . LYS C 3 27  ? 92.032  30.633  49.353  1.00 91.33  ? 243  LYS C CG  1 
ATOM   8312  C CD  . LYS C 3 27  ? 92.239  29.546  48.305  1.00 60.53  ? 243  LYS C CD  1 
ATOM   8313  C CE  . LYS C 3 27  ? 92.813  30.115  47.015  1.00 66.20  ? 243  LYS C CE  1 
ATOM   8314  N NZ  . LYS C 3 27  ? 93.182  29.047  46.041  1.00 101.35 ? 243  LYS C NZ  1 
ATOM   8315  N N   . HIS C 3 28  ? 87.471  31.761  49.598  1.00 99.61  ? 244  HIS C N   1 
ATOM   8316  C CA  . HIS C 3 28  ? 86.444  32.643  50.141  1.00 89.02  ? 244  HIS C CA  1 
ATOM   8317  C C   . HIS C 3 28  ? 86.657  32.987  51.608  1.00 84.22  ? 244  HIS C C   1 
ATOM   8318  O O   . HIS C 3 28  ? 86.079  33.970  52.086  1.00 73.07  ? 244  HIS C O   1 
ATOM   8319  C CB  . HIS C 3 28  ? 85.053  32.021  49.980  1.00 70.19  ? 244  HIS C CB  1 
ATOM   8320  C CG  . HIS C 3 28  ? 84.505  32.118  48.592  1.00 90.49  ? 244  HIS C CG  1 
ATOM   8321  N ND1 . HIS C 3 28  ? 83.692  31.151  48.041  1.00 119.13 ? 244  HIS C ND1 1 
ATOM   8322  C CD2 . HIS C 3 28  ? 84.659  33.067  47.640  1.00 109.99 ? 244  HIS C CD2 1 
ATOM   8323  C CE1 . HIS C 3 28  ? 83.363  31.503  46.811  1.00 139.18 ? 244  HIS C CE1 1 
ATOM   8324  N NE2 . HIS C 3 28  ? 83.938  32.662  46.543  1.00 137.67 ? 244  HIS C NE2 1 
ATOM   8325  N N   . LEU C 3 29  ? 87.459  32.209  52.328  1.00 84.40  ? 245  LEU C N   1 
ATOM   8326  C CA  . LEU C 3 29  ? 87.713  32.443  53.743  1.00 79.33  ? 245  LEU C CA  1 
ATOM   8327  C C   . LEU C 3 29  ? 88.902  33.361  53.988  1.00 113.41 ? 245  LEU C C   1 
ATOM   8328  O O   . LEU C 3 29  ? 89.294  33.532  55.148  1.00 133.30 ? 245  LEU C O   1 
ATOM   8329  C CB  . LEU C 3 29  ? 87.950  31.113  54.469  1.00 83.57  ? 245  LEU C CB  1 
ATOM   8330  C CG  . LEU C 3 29  ? 86.767  30.303  55.005  1.00 65.15  ? 245  LEU C CG  1 
ATOM   8331  C CD1 . LEU C 3 29  ? 86.316  30.853  56.350  1.00 80.54  ? 245  LEU C CD1 1 
ATOM   8332  C CD2 . LEU C 3 29  ? 85.614  30.261  54.024  1.00 79.02  ? 245  LEU C CD2 1 
ATOM   8333  N N   . LEU C 3 30  ? 89.470  33.947  52.927  1.00 125.43 ? 246  LEU C N   1 
ATOM   8334  C CA  . LEU C 3 30  ? 90.696  34.747  52.947  1.00 121.46 ? 246  LEU C CA  1 
ATOM   8335  C C   . LEU C 3 30  ? 90.905  35.518  54.245  1.00 131.15 ? 246  LEU C C   1 
ATOM   8336  O O   . LEU C 3 30  ? 91.969  35.421  54.865  1.00 134.74 ? 246  LEU C O   1 
ATOM   8337  C CB  . LEU C 3 30  ? 90.694  35.723  51.767  1.00 130.55 ? 246  LEU C CB  1 
ATOM   8338  C CG  . LEU C 3 30  ? 91.301  35.224  50.455  1.00 144.13 ? 246  LEU C CG  1 
ATOM   8339  C CD1 . LEU C 3 30  ? 91.077  36.232  49.336  1.00 135.65 ? 246  LEU C CD1 1 
ATOM   8340  C CD2 . LEU C 3 30  ? 92.784  34.942  50.631  1.00 148.52 ? 246  LEU C CD2 1 
ATOM   8341  N N   . LYS C 3 31  ? 89.902  36.281  54.664  1.00 144.75 ? 247  LYS C N   1 
ATOM   8342  C CA  . LYS C 3 31  ? 89.967  36.987  55.937  1.00 149.36 ? 247  LYS C CA  1 
ATOM   8343  C C   . LYS C 3 31  ? 89.294  36.174  57.037  1.00 152.53 ? 247  LYS C C   1 
ATOM   8344  O O   . LYS C 3 31  ? 89.874  35.222  57.559  1.00 166.11 ? 247  LYS C O   1 
ATOM   8345  C CB  . LYS C 3 31  ? 89.319  38.370  55.826  1.00 145.61 ? 247  LYS C CB  1 
ATOM   8346  C CG  . LYS C 3 31  ? 89.885  39.247  54.717  1.00 147.83 ? 247  LYS C CG  1 
ATOM   8347  C CD  . LYS C 3 31  ? 91.408  39.267  54.736  1.00 141.91 ? 247  LYS C CD  1 
ATOM   8348  C CE  . LYS C 3 31  ? 91.940  39.985  55.969  1.00 130.79 ? 247  LYS C CE  1 
ATOM   8349  N NZ  . LYS C 3 31  ? 91.395  41.365  56.097  1.00 119.91 ? 247  LYS C NZ  1 
ATOM   8350  N N   . MET D 1 7   ? -39.341 6.315   87.619  1.00 116.71 ? 82   MET D N   1 
ATOM   8351  C CA  . MET D 1 7   ? -38.756 6.538   86.303  1.00 113.99 ? 82   MET D CA  1 
ATOM   8352  C C   . MET D 1 7   ? -39.515 5.714   85.259  1.00 130.25 ? 82   MET D C   1 
ATOM   8353  O O   . MET D 1 7   ? -39.413 5.963   84.057  1.00 150.82 ? 82   MET D O   1 
ATOM   8354  C CB  . MET D 1 7   ? -37.254 6.199   86.328  1.00 124.79 ? 82   MET D CB  1 
ATOM   8355  C CG  . MET D 1 7   ? -36.595 5.958   84.975  1.00 134.04 ? 82   MET D CG  1 
ATOM   8356  S SD  . MET D 1 7   ? -34.887 6.545   84.897  1.00 158.62 ? 82   MET D SD  1 
ATOM   8357  C CE  . MET D 1 7   ? -34.075 5.416   86.025  1.00 139.24 ? 82   MET D CE  1 
ATOM   8358  N N   . MET D 1 8   ? -40.316 4.754   85.728  1.00 127.92 ? 83   MET D N   1 
ATOM   8359  C CA  . MET D 1 8   ? -41.062 3.886   84.824  1.00 121.14 ? 83   MET D CA  1 
ATOM   8360  C C   . MET D 1 8   ? -42.330 4.527   84.273  1.00 103.98 ? 83   MET D C   1 
ATOM   8361  O O   . MET D 1 8   ? -42.944 3.945   83.372  1.00 102.77 ? 83   MET D O   1 
ATOM   8362  C CB  . MET D 1 8   ? -41.438 2.570   85.512  1.00 100.51 ? 83   MET D CB  1 
ATOM   8363  C CG  . MET D 1 8   ? -40.267 1.760   86.028  1.00 103.67 ? 83   MET D CG  1 
ATOM   8364  S SD  . MET D 1 8   ? -40.697 0.885   87.542  1.00 121.04 ? 83   MET D SD  1 
ATOM   8365  C CE  . MET D 1 8   ? -41.061 2.259   88.632  1.00 105.83 ? 83   MET D CE  1 
ATOM   8366  N N   . LEU D 1 9   ? -42.738 5.692   84.784  1.00 82.21  ? 84   LEU D N   1 
ATOM   8367  C CA  . LEU D 1 9   ? -43.968 6.321   84.309  1.00 84.12  ? 84   LEU D CA  1 
ATOM   8368  C C   . LEU D 1 9   ? -43.922 6.544   82.802  1.00 85.67  ? 84   LEU D C   1 
ATOM   8369  O O   . LEU D 1 9   ? -44.870 6.204   82.078  1.00 81.39  ? 84   LEU D O   1 
ATOM   8370  C CB  . LEU D 1 9   ? -44.195 7.643   85.043  1.00 87.14  ? 84   LEU D CB  1 
ATOM   8371  C CG  . LEU D 1 9   ? -45.620 8.201   85.021  1.00 74.91  ? 84   LEU D CG  1 
ATOM   8372  C CD1 . LEU D 1 9   ? -46.629 7.100   85.294  1.00 64.57  ? 84   LEU D CD1 1 
ATOM   8373  C CD2 . LEU D 1 9   ? -45.775 9.335   86.023  1.00 62.28  ? 84   LEU D CD2 1 
ATOM   8374  N N   . PHE D 1 10  ? -42.816 7.108   82.311  1.00 83.89  ? 85   PHE D N   1 
ATOM   8375  C CA  . PHE D 1 10  ? -42.650 7.279   80.873  1.00 75.48  ? 85   PHE D CA  1 
ATOM   8376  C C   . PHE D 1 10  ? -42.684 5.939   80.154  1.00 83.91  ? 85   PHE D C   1 
ATOM   8377  O O   . PHE D 1 10  ? -43.267 5.826   79.072  1.00 89.32  ? 85   PHE D O   1 
ATOM   8378  C CB  . PHE D 1 10  ? -41.342 8.006   80.565  1.00 73.47  ? 85   PHE D CB  1 
ATOM   8379  C CG  . PHE D 1 10  ? -40.930 7.911   79.123  1.00 73.85  ? 85   PHE D CG  1 
ATOM   8380  C CD1 . PHE D 1 10  ? -41.674 8.537   78.137  1.00 80.34  ? 85   PHE D CD1 1 
ATOM   8381  C CD2 . PHE D 1 10  ? -39.813 7.181   78.749  1.00 84.50  ? 85   PHE D CD2 1 
ATOM   8382  C CE1 . PHE D 1 10  ? -41.308 8.447   76.806  1.00 79.69  ? 85   PHE D CE1 1 
ATOM   8383  C CE2 . PHE D 1 10  ? -39.441 7.087   77.418  1.00 84.42  ? 85   PHE D CE2 1 
ATOM   8384  C CZ  . PHE D 1 10  ? -40.190 7.721   76.446  1.00 76.42  ? 85   PHE D CZ  1 
ATOM   8385  N N   . GLU D 1 11  ? -42.062 4.911   80.737  1.00 90.43  ? 86   GLU D N   1 
ATOM   8386  C CA  . GLU D 1 11  ? -42.091 3.590   80.113  1.00 99.91  ? 86   GLU D CA  1 
ATOM   8387  C C   . GLU D 1 11  ? -43.506 3.026   80.087  1.00 103.78 ? 86   GLU D C   1 
ATOM   8388  O O   . GLU D 1 11  ? -43.917 2.410   79.094  1.00 104.65 ? 86   GLU D O   1 
ATOM   8389  C CB  . GLU D 1 11  ? -41.152 2.629   80.845  1.00 96.38  ? 86   GLU D CB  1 
ATOM   8390  C CG  . GLU D 1 11  ? -39.932 3.269   81.491  1.00 99.02  ? 86   GLU D CG  1 
ATOM   8391  C CD  . GLU D 1 11  ? -39.037 3.986   80.499  1.00 111.96 ? 86   GLU D CD  1 
ATOM   8392  O OE1 . GLU D 1 11  ? -38.796 3.435   79.404  1.00 108.25 ? 86   GLU D OE1 1 
ATOM   8393  O OE2 . GLU D 1 11  ? -38.565 5.098   80.821  1.00 106.77 ? 86   GLU D OE2 1 
ATOM   8394  N N   . VAL D 1 12  ? -44.261 3.216   81.173  1.00 92.79  ? 87   VAL D N   1 
ATOM   8395  C CA  . VAL D 1 12  ? -45.636 2.727   81.224  1.00 85.40  ? 87   VAL D CA  1 
ATOM   8396  C C   . VAL D 1 12  ? -46.479 3.393   80.146  1.00 92.33  ? 87   VAL D C   1 
ATOM   8397  O O   . VAL D 1 12  ? -47.300 2.743   79.488  1.00 94.26  ? 87   VAL D O   1 
ATOM   8398  C CB  . VAL D 1 12  ? -46.231 2.944   82.628  1.00 78.07  ? 87   VAL D CB  1 
ATOM   8399  C CG1 . VAL D 1 12  ? -47.703 2.582   82.645  1.00 91.28  ? 87   VAL D CG1 1 
ATOM   8400  C CG2 . VAL D 1 12  ? -45.482 2.112   83.651  1.00 84.16  ? 87   VAL D CG2 1 
ATOM   8401  N N   . VAL D 1 13  ? -46.284 4.696   79.937  1.00 83.97  ? 88   VAL D N   1 
ATOM   8402  C CA  . VAL D 1 13  ? -47.036 5.381   78.889  1.00 87.19  ? 88   VAL D CA  1 
ATOM   8403  C C   . VAL D 1 13  ? -46.565 4.933   77.509  1.00 101.52 ? 88   VAL D C   1 
ATOM   8404  O O   . VAL D 1 13  ? -47.371 4.767   76.584  1.00 102.86 ? 88   VAL D O   1 
ATOM   8405  C CB  . VAL D 1 13  ? -46.923 6.906   79.067  1.00 85.14  ? 88   VAL D CB  1 
ATOM   8406  C CG1 . VAL D 1 13  ? -47.446 7.637   77.837  1.00 76.75  ? 88   VAL D CG1 1 
ATOM   8407  C CG2 . VAL D 1 13  ? -47.669 7.339   80.314  1.00 77.33  ? 88   VAL D CG2 1 
ATOM   8408  N N   . LYS D 1 14  ? -45.257 4.714   77.356  1.00 96.23  ? 89   LYS D N   1 
ATOM   8409  C CA  . LYS D 1 14  ? -44.684 4.377   76.058  1.00 100.86 ? 89   LYS D CA  1 
ATOM   8410  C C   . LYS D 1 14  ? -45.165 3.013   75.582  1.00 120.58 ? 89   LYS D C   1 
ATOM   8411  O O   . LYS D 1 14  ? -45.690 2.879   74.470  1.00 118.02 ? 89   LYS D O   1 
ATOM   8412  C CB  . LYS D 1 14  ? -43.155 4.404   76.153  1.00 95.21  ? 89   LYS D CB  1 
ATOM   8413  C CG  . LYS D 1 14  ? -42.451 3.360   75.294  1.00 103.55 ? 89   LYS D CG  1 
ATOM   8414  C CD  . LYS D 1 14  ? -40.973 3.653   75.089  1.00 99.93  ? 89   LYS D CD  1 
ATOM   8415  C CE  . LYS D 1 14  ? -40.187 3.410   76.370  1.00 108.64 ? 89   LYS D CE  1 
ATOM   8416  N NZ  . LYS D 1 14  ? -38.718 3.513   76.151  1.00 97.17  ? 89   LYS D NZ  1 
ATOM   8417  N N   . MET D 1 15  ? -45.002 1.985   76.421  1.00 113.95 ? 90   MET D N   1 
ATOM   8418  C CA  . MET D 1 15  ? -45.334 0.633   75.987  1.00 115.77 ? 90   MET D CA  1 
ATOM   8419  C C   . MET D 1 15  ? -45.908 -0.220  77.113  1.00 119.97 ? 90   MET D C   1 
ATOM   8420  O O   . MET D 1 15  ? -45.911 -1.450  76.990  1.00 141.24 ? 90   MET D O   1 
ATOM   8421  C CB  . MET D 1 15  ? -44.090 -0.051  75.394  1.00 124.78 ? 90   MET D CB  1 
ATOM   8422  C CG  . MET D 1 15  ? -42.936 -0.194  76.376  1.00 112.51 ? 90   MET D CG  1 
ATOM   8423  S SD  . MET D 1 15  ? -41.810 -1.540  75.962  1.00 151.73 ? 90   MET D SD  1 
ATOM   8424  C CE  . MET D 1 15  ? -40.754 -1.555  77.411  1.00 118.60 ? 90   MET D CE  1 
ATOM   8425  N N   . GLY D 1 16  ? -46.396 0.388   78.197  1.00 126.56 ? 91   GLY D N   1 
ATOM   8426  C CA  . GLY D 1 16  ? -46.939 -0.395  79.292  1.00 132.90 ? 91   GLY D CA  1 
ATOM   8427  C C   . GLY D 1 16  ? -48.203 -1.140  78.918  1.00 131.29 ? 91   GLY D C   1 
ATOM   8428  O O   . GLY D 1 16  ? -48.515 -2.176  79.512  1.00 126.76 ? 91   GLY D O   1 
ATOM   8429  N N   . LYS D 1 17  ? -48.946 -0.622  77.936  1.00 123.12 ? 92   LYS D N   1 
ATOM   8430  C CA  . LYS D 1 17  ? -50.166 -1.258  77.437  1.00 122.50 ? 92   LYS D CA  1 
ATOM   8431  C C   . LYS D 1 17  ? -51.152 -1.490  78.592  1.00 136.67 ? 92   LYS D C   1 
ATOM   8432  O O   . LYS D 1 17  ? -51.960 -2.419  78.599  1.00 146.86 ? 92   LYS D O   1 
ATOM   8433  C CB  . LYS D 1 17  ? -49.808 -2.537  76.651  1.00 129.33 ? 92   LYS D CB  1 
ATOM   8434  C CG  . LYS D 1 17  ? -50.911 -3.535  76.318  1.00 142.02 ? 92   LYS D CG  1 
ATOM   8435  C CD  . LYS D 1 17  ? -50.742 -4.144  74.941  1.00 164.14 ? 92   LYS D CD  1 
ATOM   8436  C CE  . LYS D 1 17  ? -51.991 -4.920  74.551  1.00 167.56 ? 92   LYS D CE  1 
ATOM   8437  N NZ  . LYS D 1 17  ? -52.197 -5.000  73.078  1.00 180.55 ? 92   LYS D NZ  1 
ATOM   8438  N N   . SER D 1 18  ? -51.097 -0.617  79.593  1.00 128.17 ? 93   SER D N   1 
ATOM   8439  C CA  . SER D 1 18  ? -52.057 -0.614  80.684  1.00 110.99 ? 93   SER D CA  1 
ATOM   8440  C C   . SER D 1 18  ? -52.905 0.647   80.597  1.00 110.96 ? 93   SER D C   1 
ATOM   8441  O O   . SER D 1 18  ? -52.405 1.715   80.229  1.00 116.14 ? 93   SER D O   1 
ATOM   8442  C CB  . SER D 1 18  ? -51.360 -0.692  82.043  1.00 98.01  ? 93   SER D CB  1 
ATOM   8443  O OG  . SER D 1 18  ? -50.270 0.210   82.111  1.00 119.87 ? 93   SER D OG  1 
ATOM   8444  N N   . ALA D 1 19  ? -54.189 0.509   80.925  1.00 105.54 ? 94   ALA D N   1 
ATOM   8445  C CA  . ALA D 1 19  ? -55.139 1.605   80.786  1.00 101.96 ? 94   ALA D CA  1 
ATOM   8446  C C   . ALA D 1 19  ? -54.650 2.841   81.522  1.00 101.58 ? 94   ALA D C   1 
ATOM   8447  O O   . ALA D 1 19  ? -54.346 2.786   82.717  1.00 101.45 ? 94   ALA D O   1 
ATOM   8448  C CB  . ALA D 1 19  ? -56.509 1.180   81.313  1.00 105.64 ? 94   ALA D CB  1 
ATOM   8449  N N   . MET D 1 20  ? -54.571 3.959   80.794  1.00 97.86  ? 95   MET D N   1 
ATOM   8450  C CA  . MET D 1 20  ? -54.100 5.205   81.388  1.00 95.72  ? 95   MET D CA  1 
ATOM   8451  C C   . MET D 1 20  ? -54.945 5.608   82.591  1.00 88.12  ? 95   MET D C   1 
ATOM   8452  O O   . MET D 1 20  ? -54.458 6.310   83.486  1.00 87.47  ? 95   MET D O   1 
ATOM   8453  C CB  . MET D 1 20  ? -54.088 6.318   80.336  1.00 82.99  ? 95   MET D CB  1 
ATOM   8454  C CG  . MET D 1 20  ? -53.413 5.944   79.015  1.00 97.88  ? 95   MET D CG  1 
ATOM   8455  S SD  . MET D 1 20  ? -51.636 5.611   79.106  1.00 114.25 ? 95   MET D SD  1 
ATOM   8456  C CE  . MET D 1 20  ? -51.146 6.734   80.407  1.00 114.08 ? 95   MET D CE  1 
ATOM   8457  N N   . GLN D 1 21  ? -56.209 5.180   82.627  1.00 87.63  ? 96   GLN D N   1 
ATOM   8458  C CA  . GLN D 1 21  ? -57.036 5.390   83.811  1.00 90.78  ? 96   GLN D CA  1 
ATOM   8459  C C   . GLN D 1 21  ? -56.370 4.824   85.061  1.00 85.96  ? 96   GLN D C   1 
ATOM   8460  O O   . GLN D 1 21  ? -56.242 5.514   86.081  1.00 93.01  ? 96   GLN D O   1 
ATOM   8461  C CB  . GLN D 1 21  ? -58.411 4.760   83.594  1.00 91.48  ? 96   GLN D CB  1 
ATOM   8462  C CG  . GLN D 1 21  ? -59.229 4.533   84.865  1.00 118.55 ? 96   GLN D CG  1 
ATOM   8463  C CD  . GLN D 1 21  ? -59.634 5.814   85.592  1.00 119.22 ? 96   GLN D CD  1 
ATOM   8464  O OE1 . GLN D 1 21  ? -58.944 6.836   85.536  1.00 149.67 ? 96   GLN D OE1 1 
ATOM   8465  N NE2 . GLN D 1 21  ? -60.764 5.757   86.286  1.00 104.36 ? 96   GLN D NE2 1 
ATOM   8466  N N   . SER D 1 22  ? -55.943 3.562   84.997  1.00 90.97  ? 97   SER D N   1 
ATOM   8467  C CA  . SER D 1 22  ? -55.350 2.924   86.166  1.00 100.21 ? 97   SER D CA  1 
ATOM   8468  C C   . SER D 1 22  ? -54.042 3.600   86.553  1.00 97.27  ? 97   SER D C   1 
ATOM   8469  O O   . SER D 1 22  ? -53.751 3.773   87.742  1.00 91.54  ? 97   SER D O   1 
ATOM   8470  C CB  . SER D 1 22  ? -55.131 1.436   85.894  1.00 98.05  ? 97   SER D CB  1 
ATOM   8471  O OG  . SER D 1 22  ? -54.119 1.248   84.920  1.00 99.20  ? 97   SER D OG  1 
ATOM   8472  N N   . VAL D 1 23  ? -53.248 4.000   85.560  1.00 88.22  ? 98   VAL D N   1 
ATOM   8473  C CA  . VAL D 1 23  ? -51.983 4.676   85.836  1.00 77.92  ? 98   VAL D CA  1 
ATOM   8474  C C   . VAL D 1 23  ? -52.236 5.996   86.555  1.00 77.70  ? 98   VAL D C   1 
ATOM   8475  O O   . VAL D 1 23  ? -51.567 6.332   87.543  1.00 80.55  ? 98   VAL D O   1 
ATOM   8476  C CB  . VAL D 1 23  ? -51.196 4.881   84.529  1.00 79.56  ? 98   VAL D CB  1 
ATOM   8477  C CG1 . VAL D 1 23  ? -49.827 5.461   84.814  1.00 90.65  ? 98   VAL D CG1 1 
ATOM   8478  C CG2 . VAL D 1 23  ? -51.088 3.568   83.763  1.00 83.88  ? 98   VAL D CG2 1 
ATOM   8479  N N   . VAL D 1 24  ? -53.222 6.758   86.072  1.00 71.86  ? 99   VAL D N   1 
ATOM   8480  C CA  . VAL D 1 24  ? -53.563 8.037   86.688  1.00 69.75  ? 99   VAL D CA  1 
ATOM   8481  C C   . VAL D 1 24  ? -54.050 7.829   88.117  1.00 80.66  ? 99   VAL D C   1 
ATOM   8482  O O   . VAL D 1 24  ? -53.687 8.583   89.029  1.00 86.47  ? 99   VAL D O   1 
ATOM   8483  C CB  . VAL D 1 24  ? -54.610 8.773   85.830  1.00 69.70  ? 99   VAL D CB  1 
ATOM   8484  C CG1 . VAL D 1 24  ? -55.338 9.826   86.649  1.00 75.75  ? 99   VAL D CG1 1 
ATOM   8485  C CG2 . VAL D 1 24  ? -53.953 9.398   84.610  1.00 72.20  ? 99   VAL D CG2 1 
ATOM   8486  N N   . ASP D 1 25  ? -54.877 6.803   88.338  1.00 81.07  ? 100  ASP D N   1 
ATOM   8487  C CA  . ASP D 1 25  ? -55.376 6.544   89.686  1.00 82.99  ? 100  ASP D CA  1 
ATOM   8488  C C   . ASP D 1 25  ? -54.244 6.145   90.626  1.00 86.49  ? 100  ASP D C   1 
ATOM   8489  O O   . ASP D 1 25  ? -54.231 6.538   91.800  1.00 88.43  ? 100  ASP D O   1 
ATOM   8490  C CB  . ASP D 1 25  ? -56.453 5.461   89.652  1.00 82.72  ? 100  ASP D CB  1 
ATOM   8491  C CG  . ASP D 1 25  ? -57.702 5.909   88.922  1.00 96.94  ? 100  ASP D CG  1 
ATOM   8492  O OD1 . ASP D 1 25  ? -58.077 7.093   89.058  1.00 92.02  ? 100  ASP D OD1 1 
ATOM   8493  O OD2 . ASP D 1 25  ? -58.307 5.077   88.215  1.00 101.41 ? 100  ASP D OD2 1 
ATOM   8494  N N   . ASP D 1 26  ? -53.284 5.361   90.128  1.00 77.29  ? 101  ASP D N   1 
ATOM   8495  C CA  . ASP D 1 26  ? -52.111 5.032   90.932  1.00 65.65  ? 101  ASP D CA  1 
ATOM   8496  C C   . ASP D 1 26  ? -51.332 6.286   91.305  1.00 74.16  ? 101  ASP D C   1 
ATOM   8497  O O   . ASP D 1 26  ? -50.905 6.445   92.458  1.00 81.92  ? 101  ASP D O   1 
ATOM   8498  C CB  . ASP D 1 26  ? -51.210 4.053   90.178  1.00 70.90  ? 101  ASP D CB  1 
ATOM   8499  C CG  . ASP D 1 26  ? -51.911 2.751   89.839  1.00 83.53  ? 101  ASP D CG  1 
ATOM   8500  O OD1 . ASP D 1 26  ? -52.893 2.404   90.528  1.00 103.95 ? 101  ASP D OD1 1 
ATOM   8501  O OD2 . ASP D 1 26  ? -51.478 2.073   88.881  1.00 82.51  ? 101  ASP D OD2 1 
ATOM   8502  N N   . TRP D 1 27  ? -51.131 7.187   90.339  1.00 72.84  ? 102  TRP D N   1 
ATOM   8503  C CA  . TRP D 1 27  ? -50.422 8.427   90.644  1.00 77.45  ? 102  TRP D CA  1 
ATOM   8504  C C   . TRP D 1 27  ? -51.181 9.255   91.674  1.00 84.33  ? 102  TRP D C   1 
ATOM   8505  O O   . TRP D 1 27  ? -50.572 9.908   92.528  1.00 80.93  ? 102  TRP D O   1 
ATOM   8506  C CB  . TRP D 1 27  ? -50.189 9.251   89.379  1.00 56.47  ? 102  TRP D CB  1 
ATOM   8507  C CG  . TRP D 1 27  ? -49.366 10.473  89.666  1.00 73.56  ? 102  TRP D CG  1 
ATOM   8508  C CD1 . TRP D 1 27  ? -48.009 10.585  89.573  1.00 70.71  ? 102  TRP D CD1 1 
ATOM   8509  C CD2 . TRP D 1 27  ? -49.841 11.744  90.131  1.00 73.71  ? 102  TRP D CD2 1 
ATOM   8510  N NE1 . TRP D 1 27  ? -47.612 11.849  89.936  1.00 70.23  ? 102  TRP D NE1 1 
ATOM   8511  C CE2 . TRP D 1 27  ? -48.717 12.579  90.284  1.00 71.63  ? 102  TRP D CE2 1 
ATOM   8512  C CE3 . TRP D 1 27  ? -51.108 12.258  90.425  1.00 71.20  ? 102  TRP D CE3 1 
ATOM   8513  C CZ2 . TRP D 1 27  ? -48.821 13.897  90.717  1.00 75.43  ? 102  TRP D CZ2 1 
ATOM   8514  C CZ3 . TRP D 1 27  ? -51.207 13.565  90.856  1.00 79.34  ? 102  TRP D CZ3 1 
ATOM   8515  C CH2 . TRP D 1 27  ? -50.070 14.368  91.001  1.00 82.90  ? 102  TRP D CH2 1 
ATOM   8516  N N   . ILE D 1 28  ? -52.511 9.254   91.598  1.00 79.83  ? 103  ILE D N   1 
ATOM   8517  C CA  . ILE D 1 28  ? -53.306 10.018  92.556  1.00 77.48  ? 103  ILE D CA  1 
ATOM   8518  C C   . ILE D 1 28  ? -53.185 9.422   93.952  1.00 83.19  ? 103  ILE D C   1 
ATOM   8519  O O   . ILE D 1 28  ? -53.105 10.149  94.952  1.00 81.37  ? 103  ILE D O   1 
ATOM   8520  C CB  . ILE D 1 28  ? -54.771 10.094  92.093  1.00 65.66  ? 103  ILE D CB  1 
ATOM   8521  C CG1 . ILE D 1 28  ? -54.868 10.874  90.783  1.00 68.52  ? 103  ILE D CG1 1 
ATOM   8522  C CG2 . ILE D 1 28  ? -55.645 10.708  93.169  1.00 60.95  ? 103  ILE D CG2 1 
ATOM   8523  C CD1 . ILE D 1 28  ? -56.247 11.360  90.489  1.00 61.70  ? 103  ILE D CD1 1 
ATOM   8524  N N   . GLU D 1 29  ? -53.170 8.092   94.046  1.00 85.02  ? 104  GLU D N   1 
ATOM   8525  C CA  . GLU D 1 29  ? -52.940 7.459   95.340  1.00 85.41  ? 104  GLU D CA  1 
ATOM   8526  C C   . GLU D 1 29  ? -51.572 7.842   95.895  1.00 90.72  ? 104  GLU D C   1 
ATOM   8527  O O   . GLU D 1 29  ? -51.431 8.122   97.094  1.00 91.85  ? 104  GLU D O   1 
ATOM   8528  C CB  . GLU D 1 29  ? -53.069 5.943   95.210  1.00 93.32  ? 104  GLU D CB  1 
ATOM   8529  C CG  . GLU D 1 29  ? -54.483 5.423   95.396  1.00 106.37 ? 104  GLU D CG  1 
ATOM   8530  C CD  . GLU D 1 29  ? -54.814 5.136   96.846  1.00 125.79 ? 104  GLU D CD  1 
ATOM   8531  O OE1 . GLU D 1 29  ? -54.146 4.267   97.445  1.00 134.20 ? 104  GLU D OE1 1 
ATOM   8532  O OE2 . GLU D 1 29  ? -55.747 5.771   97.380  1.00 116.40 ? 104  GLU D OE2 1 
ATOM   8533  N N   . SER D 1 30  ? -50.554 7.874   95.028  1.00 88.64  ? 105  SER D N   1 
ATOM   8534  C CA  . SER D 1 30  ? -49.230 8.317   95.460  1.00 87.99  ? 105  SER D CA  1 
ATOM   8535  C C   . SER D 1 30  ? -49.261 9.763   95.942  1.00 88.66  ? 105  SER D C   1 
ATOM   8536  O O   . SER D 1 30  ? -48.604 10.112  96.930  1.00 87.67  ? 105  SER D O   1 
ATOM   8537  C CB  . SER D 1 30  ? -48.222 8.154   94.322  1.00 83.73  ? 105  SER D CB  1 
ATOM   8538  O OG  . SER D 1 30  ? -46.956 8.679   94.683  1.00 86.35  ? 105  SER D OG  1 
ATOM   8539  N N   . TYR D 1 31  ? -50.015 10.619  95.248  1.00 82.98  ? 106  TYR D N   1 
ATOM   8540  C CA  . TYR D 1 31  ? -50.183 12.002  95.685  1.00 80.33  ? 106  TYR D CA  1 
ATOM   8541  C C   . TYR D 1 31  ? -50.795 12.062  97.078  1.00 82.68  ? 106  TYR D C   1 
ATOM   8542  O O   . TYR D 1 31  ? -50.398 12.890  97.908  1.00 80.77  ? 106  TYR D O   1 
ATOM   8543  C CB  . TYR D 1 31  ? -51.053 12.763  94.683  1.00 74.30  ? 106  TYR D CB  1 
ATOM   8544  C CG  . TYR D 1 31  ? -51.023 14.267  94.841  1.00 84.77  ? 106  TYR D CG  1 
ATOM   8545  C CD1 . TYR D 1 31  ? -49.913 15.003  94.450  1.00 92.41  ? 106  TYR D CD1 1 
ATOM   8546  C CD2 . TYR D 1 31  ? -52.107 14.952  95.377  1.00 83.97  ? 106  TYR D CD2 1 
ATOM   8547  C CE1 . TYR D 1 31  ? -49.881 16.376  94.587  1.00 88.79  ? 106  TYR D CE1 1 
ATOM   8548  C CE2 . TYR D 1 31  ? -52.083 16.327  95.520  1.00 91.62  ? 106  TYR D CE2 1 
ATOM   8549  C CZ  . TYR D 1 31  ? -50.967 17.033  95.123  1.00 86.18  ? 106  TYR D CZ  1 
ATOM   8550  O OH  . TYR D 1 31  ? -50.934 18.401  95.262  1.00 95.92  ? 106  TYR D OH  1 
ATOM   8551  N N   . LYS D 1 32  ? -51.773 11.194  97.346  1.00 90.83  ? 107  LYS D N   1 
ATOM   8552  C CA  . LYS D 1 32  ? -52.338 11.112  98.690  1.00 87.69  ? 107  LYS D CA  1 
ATOM   8553  C C   . LYS D 1 32  ? -51.277 10.716  99.708  1.00 85.65  ? 107  LYS D C   1 
ATOM   8554  O O   . LYS D 1 32  ? -51.211 11.292  100.800 1.00 88.27  ? 107  LYS D O   1 
ATOM   8555  C CB  . LYS D 1 32  ? -53.496 10.117  98.728  1.00 85.95  ? 107  LYS D CB  1 
ATOM   8556  C CG  . LYS D 1 32  ? -54.625 10.404  97.756  1.00 72.82  ? 107  LYS D CG  1 
ATOM   8557  C CD  . LYS D 1 32  ? -55.648 9.278   97.785  1.00 92.47  ? 107  LYS D CD  1 
ATOM   8558  C CE  . LYS D 1 32  ? -56.295 9.066   96.428  1.00 92.54  ? 107  LYS D CE  1 
ATOM   8559  N NZ  . LYS D 1 32  ? -57.723 9.493   96.422  1.00 80.31  ? 107  LYS D NZ  1 
ATOM   8560  N N   . HIS D 1 33  ? -50.440 9.733   99.370  1.00 85.91  ? 108  HIS D N   1 
ATOM   8561  C CA  . HIS D 1 33  ? -49.376 9.319   100.282 1.00 90.89  ? 108  HIS D CA  1 
ATOM   8562  C C   . HIS D 1 33  ? -48.387 10.454  100.529 1.00 94.18  ? 108  HIS D C   1 
ATOM   8563  O O   . HIS D 1 33  ? -48.184 10.885  101.670 1.00 93.41  ? 108  HIS D O   1 
ATOM   8564  C CB  . HIS D 1 33  ? -48.656 8.090   99.728  1.00 86.28  ? 108  HIS D CB  1 
ATOM   8565  C CG  . HIS D 1 33  ? -48.087 7.200   100.788 1.00 99.60  ? 108  HIS D CG  1 
ATOM   8566  N ND1 . HIS D 1 33  ? -47.918 5.844   100.609 1.00 112.60 ? 108  HIS D ND1 1 
ATOM   8567  C CD2 . HIS D 1 33  ? -47.635 7.475   102.034 1.00 104.73 ? 108  HIS D CD2 1 
ATOM   8568  C CE1 . HIS D 1 33  ? -47.394 5.320   101.704 1.00 132.24 ? 108  HIS D CE1 1 
ATOM   8569  N NE2 . HIS D 1 33  ? -47.212 6.288   102.583 1.00 142.65 ? 108  HIS D NE2 1 
ATOM   8570  N N   . ASP D 1 34  ? -47.754 10.945  99.467  1.00 95.25  ? 109  ASP D N   1 
ATOM   8571  C CA  . ASP D 1 34  ? -46.806 12.050  99.562  1.00 88.96  ? 109  ASP D CA  1 
ATOM   8572  C C   . ASP D 1 34  ? -46.970 12.914  98.323  1.00 96.65  ? 109  ASP D C   1 
ATOM   8573  O O   . ASP D 1 34  ? -46.734 12.443  97.206  1.00 102.35 ? 109  ASP D O   1 
ATOM   8574  C CB  . ASP D 1 34  ? -45.368 11.540  99.686  1.00 94.93  ? 109  ASP D CB  1 
ATOM   8575  C CG  . ASP D 1 34  ? -44.379 12.645  100.010 1.00 108.38 ? 109  ASP D CG  1 
ATOM   8576  O OD1 . ASP D 1 34  ? -44.265 13.605  99.218  1.00 103.98 ? 109  ASP D OD1 1 
ATOM   8577  O OD2 . ASP D 1 34  ? -43.712 12.552  101.060 1.00 115.63 ? 109  ASP D OD2 1 
ATOM   8578  N N   . ARG D 1 35  ? -47.368 14.172  98.518  1.00 91.01  ? 110  ARG D N   1 
ATOM   8579  C CA  . ARG D 1 35  ? -47.631 15.046  97.379  1.00 84.15  ? 110  ARG D CA  1 
ATOM   8580  C C   . ARG D 1 35  ? -46.346 15.374  96.628  1.00 92.29  ? 110  ARG D C   1 
ATOM   8581  O O   . ARG D 1 35  ? -46.308 15.331  95.391  1.00 88.65  ? 110  ARG D O   1 
ATOM   8582  C CB  . ARG D 1 35  ? -48.319 16.329  97.845  1.00 84.93  ? 110  ARG D CB  1 
ATOM   8583  C CG  . ARG D 1 35  ? -49.048 16.213  99.171  1.00 107.51 ? 110  ARG D CG  1 
ATOM   8584  C CD  . ARG D 1 35  ? -49.495 17.582  99.655  1.00 108.33 ? 110  ARG D CD  1 
ATOM   8585  N NE  . ARG D 1 35  ? -50.461 18.186  98.746  1.00 118.15 ? 110  ARG D NE  1 
ATOM   8586  C CZ  . ARG D 1 35  ? -50.896 19.435  98.836  1.00 120.72 ? 110  ARG D CZ  1 
ATOM   8587  N NH1 . ARG D 1 35  ? -50.443 20.259  99.768  1.00 109.90 ? 110  ARG D NH1 1 
ATOM   8588  N NH2 . ARG D 1 35  ? -51.812 19.867  97.974  1.00 127.00 ? 110  ARG D NH2 1 
ATOM   8589  N N   . ASP D 1 36  ? -45.282 15.704  97.363  1.00 99.03  ? 111  ASP D N   1 
ATOM   8590  C CA  . ASP D 1 36  ? -44.035 16.117  96.726  1.00 95.65  ? 111  ASP D CA  1 
ATOM   8591  C C   . ASP D 1 36  ? -43.441 14.993  95.888  1.00 83.97  ? 111  ASP D C   1 
ATOM   8592  O O   . ASP D 1 36  ? -42.908 15.235  94.798  1.00 82.26  ? 111  ASP D O   1 
ATOM   8593  C CB  . ASP D 1 36  ? -43.032 16.578  97.784  1.00 86.67  ? 111  ASP D CB  1 
ATOM   8594  C CG  . ASP D 1 36  ? -43.561 17.716  98.630  1.00 104.05 ? 111  ASP D CG  1 
ATOM   8595  O OD1 . ASP D 1 36  ? -43.107 17.862  99.785  1.00 112.41 ? 111  ASP D OD1 1 
ATOM   8596  O OD2 . ASP D 1 36  ? -44.432 18.465  98.141  1.00 115.06 ? 111  ASP D OD2 1 
ATOM   8597  N N   . ILE D 1 37  ? -43.529 13.755  96.379  1.00 75.39  ? 112  ILE D N   1 
ATOM   8598  C CA  . ILE D 1 37  ? -42.931 12.627  95.672  1.00 74.75  ? 112  ILE D CA  1 
ATOM   8599  C C   . ILE D 1 37  ? -43.641 12.405  94.340  1.00 85.47  ? 112  ILE D C   1 
ATOM   8600  O O   . ILE D 1 37  ? -43.001 12.256  93.288  1.00 91.26  ? 112  ILE D O   1 
ATOM   8601  C CB  . ILE D 1 37  ? -42.963 11.368  96.561  1.00 75.50  ? 112  ILE D CB  1 
ATOM   8602  C CG1 . ILE D 1 37  ? -41.640 11.197  97.313  1.00 81.33  ? 112  ILE D CG1 1 
ATOM   8603  C CG2 . ILE D 1 37  ? -43.237 10.118  95.735  1.00 86.28  ? 112  ILE D CG2 1 
ATOM   8604  C CD1 . ILE D 1 37  ? -41.196 12.419  98.095  1.00 88.35  ? 112  ILE D CD1 1 
ATOM   8605  N N   . ALA D 1 38  ? -44.977 12.408  94.361  1.00 82.03  ? 113  ALA D N   1 
ATOM   8606  C CA  . ALA D 1 38  ? -45.739 12.231  93.131  1.00 82.10  ? 113  ALA D CA  1 
ATOM   8607  C C   . ALA D 1 38  ? -45.533 13.403  92.180  1.00 80.71  ? 113  ALA D C   1 
ATOM   8608  O O   . ALA D 1 38  ? -45.483 13.216  90.958  1.00 79.80  ? 113  ALA D O   1 
ATOM   8609  C CB  . ALA D 1 38  ? -47.222 12.050  93.452  1.00 79.33  ? 113  ALA D CB  1 
ATOM   8610  N N   . LEU D 1 39  ? -45.403 14.619  92.717  1.00 74.13  ? 114  LEU D N   1 
ATOM   8611  C CA  . LEU D 1 39  ? -45.143 15.773  91.861  1.00 74.70  ? 114  LEU D CA  1 
ATOM   8612  C C   . LEU D 1 39  ? -43.792 15.655  91.172  1.00 79.01  ? 114  LEU D C   1 
ATOM   8613  O O   . LEU D 1 39  ? -43.656 15.996  89.990  1.00 75.47  ? 114  LEU D O   1 
ATOM   8614  C CB  . LEU D 1 39  ? -45.215 17.064  92.673  1.00 74.23  ? 114  LEU D CB  1 
ATOM   8615  C CG  . LEU D 1 39  ? -46.624 17.553  92.981  1.00 70.73  ? 114  LEU D CG  1 
ATOM   8616  C CD1 . LEU D 1 39  ? -46.578 18.957  93.546  1.00 75.34  ? 114  LEU D CD1 1 
ATOM   8617  C CD2 . LEU D 1 39  ? -47.446 17.508  91.711  1.00 75.58  ? 114  LEU D CD2 1 
ATOM   8618  N N   . LEU D 1 40  ? -42.776 15.194  91.903  1.00 86.15  ? 115  LEU D N   1 
ATOM   8619  C CA  . LEU D 1 40  ? -41.473 14.961  91.294  1.00 77.83  ? 115  LEU D CA  1 
ATOM   8620  C C   . LEU D 1 40  ? -41.566 13.906  90.200  1.00 74.98  ? 115  LEU D C   1 
ATOM   8621  O O   . LEU D 1 40  ? -40.984 14.065  89.118  1.00 74.93  ? 115  LEU D O   1 
ATOM   8622  C CB  . LEU D 1 40  ? -40.465 14.544  92.364  1.00 65.82  ? 115  LEU D CB  1 
ATOM   8623  C CG  . LEU D 1 40  ? -39.011 14.430  91.908  1.00 74.65  ? 115  LEU D CG  1 
ATOM   8624  C CD1 . LEU D 1 40  ? -38.491 15.775  91.422  1.00 82.72  ? 115  LEU D CD1 1 
ATOM   8625  C CD2 . LEU D 1 40  ? -38.147 13.884  93.032  1.00 90.12  ? 115  LEU D CD2 1 
ATOM   8626  N N   . ASP D 1 41  ? -42.303 12.822  90.462  1.00 81.11  ? 116  ASP D N   1 
ATOM   8627  C CA  . ASP D 1 41  ? -42.468 11.790  89.442  1.00 75.58  ? 116  ASP D CA  1 
ATOM   8628  C C   . ASP D 1 41  ? -43.180 12.331  88.208  1.00 71.33  ? 116  ASP D C   1 
ATOM   8629  O O   . ASP D 1 41  ? -42.854 11.945  87.085  1.00 74.53  ? 116  ASP D O   1 
ATOM   8630  C CB  . ASP D 1 41  ? -43.216 10.585  90.011  1.00 70.30  ? 116  ASP D CB  1 
ATOM   8631  C CG  . ASP D 1 41  ? -42.601 10.077  91.293  1.00 90.25  ? 116  ASP D CG  1 
ATOM   8632  O OD1 . ASP D 1 41  ? -41.395 10.328  91.507  1.00 96.23  ? 116  ASP D OD1 1 
ATOM   8633  O OD2 . ASP D 1 41  ? -43.316 9.422   92.080  1.00 89.99  ? 116  ASP D OD2 1 
ATOM   8634  N N   . LEU D 1 42  ? -44.135 13.246  88.390  1.00 71.73  ? 117  LEU D N   1 
ATOM   8635  C CA  . LEU D 1 42  ? -44.857 13.804  87.245  1.00 60.92  ? 117  LEU D CA  1 
ATOM   8636  C C   . LEU D 1 42  ? -43.973 14.752  86.435  1.00 71.93  ? 117  LEU D C   1 
ATOM   8637  O O   . LEU D 1 42  ? -43.976 14.721  85.192  1.00 76.03  ? 117  LEU D O   1 
ATOM   8638  C CB  . LEU D 1 42  ? -46.116 14.524  87.732  1.00 54.34  ? 117  LEU D CB  1 
ATOM   8639  C CG  . LEU D 1 42  ? -47.233 14.850  86.737  1.00 63.53  ? 117  LEU D CG  1 
ATOM   8640  C CD1 . LEU D 1 42  ? -47.586 13.631  85.904  1.00 64.78  ? 117  LEU D CD1 1 
ATOM   8641  C CD2 . LEU D 1 42  ? -48.462 15.376  87.464  1.00 61.02  ? 117  LEU D CD2 1 
ATOM   8642  N N   . ILE D 1 43  ? -43.233 15.622  87.129  1.00 68.03  ? 118  ILE D N   1 
ATOM   8643  C CA  . ILE D 1 43  ? -42.255 16.484  86.468  1.00 66.32  ? 118  ILE D CA  1 
ATOM   8644  C C   . ILE D 1 43  ? -41.315 15.643  85.619  1.00 65.67  ? 118  ILE D C   1 
ATOM   8645  O O   . ILE D 1 43  ? -41.112 15.902  84.423  1.00 69.20  ? 118  ILE D O   1 
ATOM   8646  C CB  . ILE D 1 43  ? -41.473 17.299  87.512  1.00 64.90  ? 118  ILE D CB  1 
ATOM   8647  C CG1 . ILE D 1 43  ? -42.371 18.351  88.161  1.00 64.72  ? 118  ILE D CG1 1 
ATOM   8648  C CG2 . ILE D 1 43  ? -40.254 17.944  86.873  1.00 55.50  ? 118  ILE D CG2 1 
ATOM   8649  C CD1 . ILE D 1 43  ? -41.924 18.742  89.553  1.00 77.14  ? 118  ILE D CD1 1 
ATOM   8650  N N   . ASN D 1 44  ? -40.733 14.611  86.234  1.00 58.00  ? 119  ASN D N   1 
ATOM   8651  C CA  . ASN D 1 44  ? -39.840 13.732  85.496  1.00 66.52  ? 119  ASN D CA  1 
ATOM   8652  C C   . ASN D 1 44  ? -40.572 13.000  84.383  1.00 69.29  ? 119  ASN D C   1 
ATOM   8653  O O   . ASN D 1 44  ? -39.978 12.720  83.345  1.00 73.23  ? 119  ASN D O   1 
ATOM   8654  C CB  . ASN D 1 44  ? -39.169 12.740  86.443  1.00 66.82  ? 119  ASN D CB  1 
ATOM   8655  C CG  . ASN D 1 44  ? -37.958 13.329  87.133  1.00 63.11  ? 119  ASN D CG  1 
ATOM   8656  O OD1 . ASN D 1 44  ? -36.951 13.627  86.493  1.00 65.29  ? 119  ASN D OD1 1 
ATOM   8657  N ND2 . ASN D 1 44  ? -38.050 13.502  88.446  1.00 76.06  ? 119  ASN D ND2 1 
ATOM   8658  N N   . PHE D 1 45  ? -41.852 12.678  84.570  1.00 65.26  ? 120  PHE D N   1 
ATOM   8659  C CA  . PHE D 1 45  ? -42.611 12.041  83.500  1.00 62.03  ? 120  PHE D CA  1 
ATOM   8660  C C   . PHE D 1 45  ? -42.609 12.912  82.254  1.00 65.80  ? 120  PHE D C   1 
ATOM   8661  O O   . PHE D 1 45  ? -42.310 12.441  81.152  1.00 66.93  ? 120  PHE D O   1 
ATOM   8662  C CB  . PHE D 1 45  ? -44.043 11.759  83.959  1.00 59.48  ? 120  PHE D CB  1 
ATOM   8663  C CG  . PHE D 1 45  ? -45.014 11.558  82.828  1.00 70.91  ? 120  PHE D CG  1 
ATOM   8664  C CD1 . PHE D 1 45  ? -45.044 10.361  82.130  1.00 66.93  ? 120  PHE D CD1 1 
ATOM   8665  C CD2 . PHE D 1 45  ? -45.894 12.563  82.460  1.00 66.32  ? 120  PHE D CD2 1 
ATOM   8666  C CE1 . PHE D 1 45  ? -45.932 10.170  81.092  1.00 45.88  ? 120  PHE D CE1 1 
ATOM   8667  C CE2 . PHE D 1 45  ? -46.783 12.377  81.419  1.00 59.42  ? 120  PHE D CE2 1 
ATOM   8668  C CZ  . PHE D 1 45  ? -46.802 11.178  80.734  1.00 50.28  ? 120  PHE D CZ  1 
ATOM   8669  N N   . PHE D 1 46  ? -42.921 14.198  82.419  1.00 62.46  ? 121  PHE D N   1 
ATOM   8670  C CA  . PHE D 1 46  ? -42.883 15.106  81.273  1.00 61.40  ? 121  PHE D CA  1 
ATOM   8671  C C   . PHE D 1 46  ? -41.471 15.210  80.693  1.00 72.38  ? 121  PHE D C   1 
ATOM   8672  O O   . PHE D 1 46  ? -41.284 15.151  79.466  1.00 59.94  ? 121  PHE D O   1 
ATOM   8673  C CB  . PHE D 1 46  ? -43.413 16.481  81.678  1.00 49.43  ? 121  PHE D CB  1 
ATOM   8674  C CG  . PHE D 1 46  ? -44.899 16.512  81.889  1.00 63.78  ? 121  PHE D CG  1 
ATOM   8675  C CD1 . PHE D 1 46  ? -45.767 16.173  80.864  1.00 61.53  ? 121  PHE D CD1 1 
ATOM   8676  C CD2 . PHE D 1 46  ? -45.428 16.863  83.119  1.00 67.93  ? 121  PHE D CD2 1 
ATOM   8677  C CE1 . PHE D 1 46  ? -47.136 16.193  81.060  1.00 49.92  ? 121  PHE D CE1 1 
ATOM   8678  C CE2 . PHE D 1 46  ? -46.795 16.885  83.323  1.00 42.36  ? 121  PHE D CE2 1 
ATOM   8679  C CZ  . PHE D 1 46  ? -47.650 16.549  82.292  1.00 43.99  ? 121  PHE D CZ  1 
ATOM   8680  N N   . ILE D 1 47  ? -40.463 15.335  81.564  1.00 68.93  ? 122  ILE D N   1 
ATOM   8681  C CA  . ILE D 1 47  ? -39.079 15.464  81.099  1.00 60.36  ? 122  ILE D CA  1 
ATOM   8682  C C   . ILE D 1 47  ? -38.679 14.261  80.246  1.00 60.59  ? 122  ILE D C   1 
ATOM   8683  O O   . ILE D 1 47  ? -38.145 14.411  79.140  1.00 59.08  ? 122  ILE D O   1 
ATOM   8684  C CB  . ILE D 1 47  ? -38.127 15.653  82.294  1.00 60.34  ? 122  ILE D CB  1 
ATOM   8685  C CG1 . ILE D 1 47  ? -38.433 16.967  83.018  1.00 57.36  ? 122  ILE D CG1 1 
ATOM   8686  C CG2 . ILE D 1 47  ? -36.681 15.618  81.837  1.00 68.74  ? 122  ILE D CG2 1 
ATOM   8687  C CD1 . ILE D 1 47  ? -38.066 18.200  82.220  1.00 63.35  ? 122  ILE D CD1 1 
ATOM   8688  N N   . GLN D 1 48  ? -38.932 13.050  80.750  1.00 53.29  ? 123  GLN D N   1 
ATOM   8689  C CA  . GLN D 1 48  ? -38.606 11.829  80.017  1.00 61.30  ? 123  GLN D CA  1 
ATOM   8690  C C   . GLN D 1 48  ? -39.427 11.706  78.739  1.00 64.20  ? 123  GLN D C   1 
ATOM   8691  O O   . GLN D 1 48  ? -38.933 11.198  77.726  1.00 68.77  ? 123  GLN D O   1 
ATOM   8692  C CB  . GLN D 1 48  ? -38.828 10.606  80.913  1.00 62.94  ? 123  GLN D CB  1 
ATOM   8693  C CG  . GLN D 1 48  ? -38.229 10.730  82.308  1.00 62.18  ? 123  GLN D CG  1 
ATOM   8694  C CD  . GLN D 1 48  ? -37.744 9.421   82.886  1.00 82.50  ? 123  GLN D CD  1 
ATOM   8695  O OE1 . GLN D 1 48  ? -38.004 8.351   82.337  1.00 92.82  ? 123  GLN D OE1 1 
ATOM   8696  N NE2 . GLN D 1 48  ? -37.054 9.497   84.019  1.00 88.31  ? 123  GLN D NE2 1 
ATOM   8697  N N   . CYS D 1 49  ? -40.691 12.146  78.769  1.00 68.45  ? 124  CYS D N   1 
ATOM   8698  C CA  . CYS D 1 49  ? -41.487 12.174  77.546  1.00 63.71  ? 124  CYS D CA  1 
ATOM   8699  C C   . CYS D 1 49  ? -40.851 13.062  76.490  1.00 66.05  ? 124  CYS D C   1 
ATOM   8700  O O   . CYS D 1 49  ? -41.040 12.832  75.289  1.00 60.25  ? 124  CYS D O   1 
ATOM   8701  C CB  . CYS D 1 49  ? -42.910 12.648  77.838  1.00 59.40  ? 124  CYS D CB  1 
ATOM   8702  S SG  . CYS D 1 49  ? -43.940 11.440  78.682  1.00 69.33  ? 124  CYS D SG  1 
ATOM   8703  N N   . SER D 1 50  ? -40.097 14.076  76.911  1.00 63.63  ? 125  SER D N   1 
ATOM   8704  C CA  . SER D 1 50  ? -39.327 14.823  75.921  1.00 71.75  ? 125  SER D CA  1 
ATOM   8705  C C   . SER D 1 50  ? -38.113 14.055  75.397  1.00 74.59  ? 125  SER D C   1 
ATOM   8706  O O   . SER D 1 50  ? -37.351 14.616  74.601  1.00 72.96  ? 125  SER D O   1 
ATOM   8707  C CB  . SER D 1 50  ? -38.872 16.161  76.501  1.00 68.94  ? 125  SER D CB  1 
ATOM   8708  O OG  . SER D 1 50  ? -39.971 16.893  77.010  1.00 78.53  ? 125  SER D OG  1 
ATOM   8709  N N   . GLY D 1 51  ? -37.915 12.800  75.805  1.00 73.52  ? 126  GLY D N   1 
ATOM   8710  C CA  . GLY D 1 51  ? -36.757 12.032  75.402  1.00 72.85  ? 126  GLY D CA  1 
ATOM   8711  C C   . GLY D 1 51  ? -35.539 12.208  76.281  1.00 70.74  ? 126  GLY D C   1 
ATOM   8712  O O   . GLY D 1 51  ? -34.561 11.468  76.109  1.00 67.55  ? 126  GLY D O   1 
ATOM   8713  N N   . CYS D 1 52  ? -35.565 13.162  77.210  1.00 70.27  ? 127  CYS D N   1 
ATOM   8714  C CA  . CYS D 1 52  ? -34.438 13.388  78.105  1.00 69.43  ? 127  CYS D CA  1 
ATOM   8715  C C   . CYS D 1 52  ? -34.159 12.151  78.948  1.00 75.51  ? 127  CYS D C   1 
ATOM   8716  O O   . CYS D 1 52  ? -35.077 11.547  79.511  1.00 65.82  ? 127  CYS D O   1 
ATOM   8717  C CB  . CYS D 1 52  ? -34.721 14.590  79.006  1.00 65.91  ? 127  CYS D CB  1 
ATOM   8718  S SG  . CYS D 1 52  ? -33.332 15.113  80.034  1.00 76.48  ? 127  CYS D SG  1 
ATOM   8719  N N   . LYS D 1 53  ? -32.885 11.772  79.029  1.00 76.53  ? 128  LYS D N   1 
ATOM   8720  C CA  . LYS D 1 53  ? -32.472 10.646  79.854  1.00 68.73  ? 128  LYS D CA  1 
ATOM   8721  C C   . LYS D 1 53  ? -32.163 11.045  81.290  1.00 65.39  ? 128  LYS D C   1 
ATOM   8722  O O   . LYS D 1 53  ? -31.888 10.166  82.113  1.00 77.91  ? 128  LYS D O   1 
ATOM   8723  C CB  . LYS D 1 53  ? -31.243 9.958   79.245  1.00 68.77  ? 128  LYS D CB  1 
ATOM   8724  C CG  . LYS D 1 53  ? -31.573 8.906   78.196  1.00 70.58  ? 128  LYS D CG  1 
ATOM   8725  C CD  . LYS D 1 53  ? -31.583 9.500   76.794  1.00 89.44  ? 128  LYS D CD  1 
ATOM   8726  C CE  . LYS D 1 53  ? -31.944 8.462   75.740  1.00 95.61  ? 128  LYS D CE  1 
ATOM   8727  N NZ  . LYS D 1 53  ? -32.579 9.080   74.539  1.00 95.71  ? 128  LYS D NZ  1 
ATOM   8728  N N   . GLY D 1 54  ? -32.204 12.338  81.610  1.00 56.25  ? 129  GLY D N   1 
ATOM   8729  C CA  . GLY D 1 54  ? -31.893 12.780  82.950  1.00 63.66  ? 129  GLY D CA  1 
ATOM   8730  C C   . GLY D 1 54  ? -33.086 12.715  83.884  1.00 74.39  ? 129  GLY D C   1 
ATOM   8731  O O   . GLY D 1 54  ? -34.234 12.539  83.475  1.00 91.46  ? 129  GLY D O   1 
ATOM   8732  N N   . VAL D 1 55  ? -32.795 12.877  85.173  1.00 71.23  ? 130  VAL D N   1 
ATOM   8733  C CA  . VAL D 1 55  ? -33.793 12.801  86.232  1.00 70.94  ? 130  VAL D CA  1 
ATOM   8734  C C   . VAL D 1 55  ? -33.667 14.037  87.111  1.00 67.65  ? 130  VAL D C   1 
ATOM   8735  O O   . VAL D 1 55  ? -32.555 14.463  87.441  1.00 71.77  ? 130  VAL D O   1 
ATOM   8736  C CB  . VAL D 1 55  ? -33.631 11.514  87.070  1.00 66.96  ? 130  VAL D CB  1 
ATOM   8737  C CG1 . VAL D 1 55  ? -34.610 11.504  88.233  1.00 84.82  ? 130  VAL D CG1 1 
ATOM   8738  C CG2 . VAL D 1 55  ? -33.823 10.285  86.195  1.00 79.04  ? 130  VAL D CG2 1 
ATOM   8739  N N   . VAL D 1 56  ? -34.807 14.610  87.487  1.00 75.96  ? 131  VAL D N   1 
ATOM   8740  C CA  . VAL D 1 56  ? -34.845 15.795  88.337  1.00 73.93  ? 131  VAL D CA  1 
ATOM   8741  C C   . VAL D 1 56  ? -34.795 15.362  89.796  1.00 78.03  ? 131  VAL D C   1 
ATOM   8742  O O   . VAL D 1 56  ? -35.562 14.491  90.225  1.00 62.54  ? 131  VAL D O   1 
ATOM   8743  C CB  . VAL D 1 56  ? -36.103 16.633  88.056  1.00 64.34  ? 131  VAL D CB  1 
ATOM   8744  C CG1 . VAL D 1 56  ? -36.113 17.881  88.923  1.00 66.99  ? 131  VAL D CG1 1 
ATOM   8745  C CG2 . VAL D 1 56  ? -36.176 16.999  86.584  1.00 64.10  ? 131  VAL D CG2 1 
ATOM   8746  N N   . THR D 1 57  ? -33.893 15.972  90.560  1.00 79.38  ? 132  THR D N   1 
ATOM   8747  C CA  . THR D 1 57  ? -33.754 15.652  91.971  1.00 83.13  ? 132  THR D CA  1 
ATOM   8748  C C   . THR D 1 57  ? -34.826 16.360  92.794  1.00 93.36  ? 132  THR D C   1 
ATOM   8749  O O   . THR D 1 57  ? -35.445 17.334  92.355  1.00 92.93  ? 132  THR D O   1 
ATOM   8750  C CB  . THR D 1 57  ? -32.369 16.047  92.483  1.00 90.35  ? 132  THR D CB  1 
ATOM   8751  O OG1 . THR D 1 57  ? -32.390 17.415  92.910  1.00 92.45  ? 132  THR D OG1 1 
ATOM   8752  C CG2 . THR D 1 57  ? -31.325 15.874  91.391  1.00 97.65  ? 132  THR D CG2 1 
ATOM   8753  N N   . ALA D 1 58  ? -35.038 15.848  94.009  1.00 87.34  ? 133  ALA D N   1 
ATOM   8754  C CA  . ALA D 1 58  ? -35.981 16.481  94.924  1.00 77.23  ? 133  ALA D CA  1 
ATOM   8755  C C   . ALA D 1 58  ? -35.497 17.864  95.339  1.00 93.39  ? 133  ALA D C   1 
ATOM   8756  O O   . ALA D 1 58  ? -36.298 18.799  95.468  1.00 95.02  ? 133  ALA D O   1 
ATOM   8757  C CB  . ALA D 1 58  ? -36.195 15.594  96.149  1.00 88.89  ? 133  ALA D CB  1 
ATOM   8758  N N   . GLU D 1 59  ? -34.186 18.013  95.550  1.00 94.30  ? 134  GLU D N   1 
ATOM   8759  C CA  . GLU D 1 59  ? -33.633 19.322  95.881  1.00 100.23 ? 134  GLU D CA  1 
ATOM   8760  C C   . GLU D 1 59  ? -33.846 20.310  94.741  1.00 87.70  ? 134  GLU D C   1 
ATOM   8761  O O   . GLU D 1 59  ? -34.122 21.493  94.975  1.00 85.94  ? 134  GLU D O   1 
ATOM   8762  C CB  . GLU D 1 59  ? -32.145 19.197  96.211  1.00 109.92 ? 134  GLU D CB  1 
ATOM   8763  C CG  . GLU D 1 59  ? -31.770 17.928  96.960  1.00 123.86 ? 134  GLU D CG  1 
ATOM   8764  C CD  . GLU D 1 59  ? -32.531 17.770  98.261  1.00 145.98 ? 134  GLU D CD  1 
ATOM   8765  O OE1 . GLU D 1 59  ? -32.417 18.657  99.134  1.00 141.57 ? 134  GLU D OE1 1 
ATOM   8766  O OE2 . GLU D 1 59  ? -33.242 16.754  98.412  1.00 169.84 ? 134  GLU D OE2 1 
ATOM   8767  N N   . MET D 1 60  ? -33.717 19.839  93.498  1.00 85.63  ? 135  MET D N   1 
ATOM   8768  C CA  . MET D 1 60  ? -33.993 20.683  92.340  1.00 88.31  ? 135  MET D CA  1 
ATOM   8769  C C   . MET D 1 60  ? -35.417 21.219  92.387  1.00 84.22  ? 135  MET D C   1 
ATOM   8770  O O   . MET D 1 60  ? -35.647 22.427  92.261  1.00 88.04  ? 135  MET D O   1 
ATOM   8771  C CB  . MET D 1 60  ? -33.768 19.890  91.052  1.00 83.41  ? 135  MET D CB  1 
ATOM   8772  C CG  . MET D 1 60  ? -32.325 19.813  90.589  1.00 75.35  ? 135  MET D CG  1 
ATOM   8773  S SD  . MET D 1 60  ? -32.209 19.727  88.791  1.00 103.88 ? 135  MET D SD  1 
ATOM   8774  C CE  . MET D 1 60  ? -31.612 18.054  88.559  1.00 81.29  ? 135  MET D CE  1 
ATOM   8775  N N   . PHE D 1 61  ? -36.387 20.324  92.574  1.00 84.69  ? 136  PHE D N   1 
ATOM   8776  C CA  . PHE D 1 61  ? -37.787 20.727  92.628  1.00 91.67  ? 136  PHE D CA  1 
ATOM   8777  C C   . PHE D 1 61  ? -38.066 21.636  93.819  1.00 87.79  ? 136  PHE D C   1 
ATOM   8778  O O   . PHE D 1 61  ? -38.951 22.495  93.752  1.00 85.46  ? 136  PHE D O   1 
ATOM   8779  C CB  . PHE D 1 61  ? -38.665 19.472  92.667  1.00 82.48  ? 136  PHE D CB  1 
ATOM   8780  C CG  . PHE D 1 61  ? -40.008 19.675  93.305  1.00 83.05  ? 136  PHE D CG  1 
ATOM   8781  C CD1 . PHE D 1 61  ? -41.029 20.306  92.615  1.00 74.52  ? 136  PHE D CD1 1 
ATOM   8782  C CD2 . PHE D 1 61  ? -40.259 19.207  94.585  1.00 113.67 ? 136  PHE D CD2 1 
ATOM   8783  C CE1 . PHE D 1 61  ? -42.270 20.484  93.196  1.00 85.13  ? 136  PHE D CE1 1 
ATOM   8784  C CE2 . PHE D 1 61  ? -41.498 19.382  95.173  1.00 116.15 ? 136  PHE D CE2 1 
ATOM   8785  C CZ  . PHE D 1 61  ? -42.506 20.022  94.476  1.00 97.16  ? 136  PHE D CZ  1 
ATOM   8786  N N   . ARG D 1 62  ? -37.309 21.480  94.905  1.00 83.06  ? 137  ARG D N   1 
ATOM   8787  C CA  . ARG D 1 62  ? -37.573 22.248  96.118  1.00 93.75  ? 137  ARG D CA  1 
ATOM   8788  C C   . ARG D 1 62  ? -36.985 23.659  96.041  1.00 99.45  ? 137  ARG D C   1 
ATOM   8789  O O   . ARG D 1 62  ? -37.660 24.635  96.391  1.00 102.61 ? 137  ARG D O   1 
ATOM   8790  C CB  . ARG D 1 62  ? -37.032 21.486  97.334  1.00 104.03 ? 137  ARG D CB  1 
ATOM   8791  C CG  . ARG D 1 62  ? -36.591 22.370  98.481  1.00 110.42 ? 137  ARG D CG  1 
ATOM   8792  C CD  . ARG D 1 62  ? -36.414 21.690  99.864  1.00 130.31 ? 137  ARG D CD  1 
ATOM   8793  N NE  . ARG D 1 62  ? -37.494 20.865  100.410 1.00 148.52 ? 137  ARG D NE  1 
ATOM   8794  C CZ  . ARG D 1 62  ? -37.755 19.602  100.095 1.00 166.25 ? 137  ARG D CZ  1 
ATOM   8795  N NH1 . ARG D 1 62  ? -37.076 18.962  99.156  1.00 171.15 ? 137  ARG D NH1 1 
ATOM   8796  N NH2 . ARG D 1 62  ? -38.707 18.953  100.764 1.00 177.61 ? 137  ARG D NH2 1 
ATOM   8797  N N   . HIS D 1 63  ? -35.736 23.791  95.585  1.00 102.42 ? 138  HIS D N   1 
ATOM   8798  C CA  . HIS D 1 63  ? -35.062 25.083  95.491  1.00 94.86  ? 138  HIS D CA  1 
ATOM   8799  C C   . HIS D 1 63  ? -34.908 25.592  94.065  1.00 83.83  ? 138  HIS D C   1 
ATOM   8800  O O   . HIS D 1 63  ? -35.265 26.740  93.777  1.00 83.48  ? 138  HIS D O   1 
ATOM   8801  C CB  . HIS D 1 63  ? -33.670 25.027  96.147  1.00 99.50  ? 138  HIS D CB  1 
ATOM   8802  C CG  . HIS D 1 63  ? -33.570 24.104  97.321  1.00 108.23 ? 138  HIS D CG  1 
ATOM   8803  N ND1 . HIS D 1 63  ? -33.007 22.849  97.238  1.00 125.16 ? 138  HIS D ND1 1 
ATOM   8804  C CD2 . HIS D 1 63  ? -33.895 24.283  98.623  1.00 93.65  ? 138  HIS D CD2 1 
ATOM   8805  C CE1 . HIS D 1 63  ? -33.026 22.278  98.429  1.00 113.86 ? 138  HIS D CE1 1 
ATOM   8806  N NE2 . HIS D 1 63  ? -33.557 23.129  99.289  1.00 112.41 ? 138  HIS D NE2 1 
ATOM   8807  N N   . MET D 1 64  ? -34.360 24.774  93.167  1.00 91.18  ? 139  MET D N   1 
ATOM   8808  C CA  . MET D 1 64  ? -34.003 25.239  91.832  1.00 92.51  ? 139  MET D CA  1 
ATOM   8809  C C   . MET D 1 64  ? -35.235 25.690  91.057  1.00 83.76  ? 139  MET D C   1 
ATOM   8810  O O   . MET D 1 64  ? -36.282 25.039  91.085  1.00 100.55 ? 139  MET D O   1 
ATOM   8811  C CB  . MET D 1 64  ? -33.285 24.121  91.074  1.00 89.63  ? 139  MET D CB  1 
ATOM   8812  C CG  . MET D 1 64  ? -32.083 24.561  90.263  1.00 82.77  ? 139  MET D CG  1 
ATOM   8813  S SD  . MET D 1 64  ? -31.465 23.200  89.256  1.00 92.70  ? 139  MET D SD  1 
ATOM   8814  C CE  . MET D 1 64  ? -29.981 22.754  90.156  1.00 98.09  ? 139  MET D CE  1 
ATOM   8815  N N   . GLN D 1 65  ? -35.106 26.822  90.370  1.00 72.15  ? 140  GLN D N   1 
ATOM   8816  C CA  . GLN D 1 65  ? -36.181 27.303  89.518  1.00 85.61  ? 140  GLN D CA  1 
ATOM   8817  C C   . GLN D 1 65  ? -36.267 26.434  88.264  1.00 83.44  ? 140  GLN D C   1 
ATOM   8818  O O   . GLN D 1 65  ? -35.298 25.779  87.866  1.00 76.39  ? 140  GLN D O   1 
ATOM   8819  C CB  . GLN D 1 65  ? -35.949 28.770  89.150  1.00 78.80  ? 140  GLN D CB  1 
ATOM   8820  C CG  . GLN D 1 65  ? -37.212 29.620  89.054  1.00 85.60  ? 140  GLN D CG  1 
ATOM   8821  C CD  . GLN D 1 65  ? -37.907 29.507  87.706  1.00 106.80 ? 140  GLN D CD  1 
ATOM   8822  O OE1 . GLN D 1 65  ? -37.371 28.931  86.761  1.00 102.36 ? 140  GLN D OE1 1 
ATOM   8823  N NE2 . GLN D 1 65  ? -39.101 30.083  87.607  1.00 97.28  ? 140  GLN D NE2 1 
ATOM   8824  N N   . ASN D 1 66  ? -37.451 26.427  87.641  1.00 87.09  ? 141  ASN D N   1 
ATOM   8825  C CA  . ASN D 1 66  ? -37.682 25.554  86.490  1.00 68.02  ? 141  ASN D CA  1 
ATOM   8826  C C   . ASN D 1 66  ? -36.669 25.795  85.378  1.00 72.56  ? 141  ASN D C   1 
ATOM   8827  O O   . ASN D 1 66  ? -36.250 24.852  84.702  1.00 70.96  ? 141  ASN D O   1 
ATOM   8828  C CB  . ASN D 1 66  ? -39.104 25.735  85.948  1.00 73.38  ? 141  ASN D CB  1 
ATOM   8829  C CG  . ASN D 1 66  ? -40.137 24.930  86.716  1.00 76.42  ? 141  ASN D CG  1 
ATOM   8830  O OD1 . ASN D 1 66  ? -39.921 23.760  87.030  1.00 86.31  ? 141  ASN D OD1 1 
ATOM   8831  N ND2 . ASN D 1 66  ? -41.284 25.541  86.983  1.00 76.35  ? 141  ASN D ND2 1 
ATOM   8832  N N   . SER D 1 67  ? -36.264 27.050  85.172  1.00 70.96  ? 142  SER D N   1 
ATOM   8833  C CA  . SER D 1 67  ? -35.334 27.363  84.091  1.00 67.09  ? 142  SER D CA  1 
ATOM   8834  C C   . SER D 1 67  ? -33.998 26.652  84.284  1.00 70.05  ? 142  SER D C   1 
ATOM   8835  O O   . SER D 1 67  ? -33.469 26.026  83.355  1.00 70.95  ? 142  SER D O   1 
ATOM   8836  C CB  . SER D 1 67  ? -35.133 28.876  84.003  1.00 76.82  ? 142  SER D CB  1 
ATOM   8837  O OG  . SER D 1 67  ? -34.539 29.376  85.188  1.00 69.62  ? 142  SER D OG  1 
ATOM   8838  N N   . GLU D 1 68  ? -33.434 26.741  85.490  1.00 66.71  ? 143  GLU D N   1 
ATOM   8839  C CA  . GLU D 1 68  ? -32.161 26.081  85.756  1.00 68.77  ? 143  GLU D CA  1 
ATOM   8840  C C   . GLU D 1 68  ? -32.306 24.565  85.706  1.00 68.92  ? 143  GLU D C   1 
ATOM   8841  O O   . GLU D 1 68  ? -31.388 23.861  85.268  1.00 76.65  ? 143  GLU D O   1 
ATOM   8842  C CB  . GLU D 1 68  ? -31.612 26.526  87.110  1.00 77.54  ? 143  GLU D CB  1 
ATOM   8843  C CG  . GLU D 1 68  ? -30.270 25.913  87.449  1.00 93.51  ? 143  GLU D CG  1 
ATOM   8844  C CD  . GLU D 1 68  ? -29.484 26.740  88.437  1.00 98.44  ? 143  GLU D CD  1 
ATOM   8845  O OE1 . GLU D 1 68  ? -29.893 27.888  88.712  1.00 103.97 ? 143  GLU D OE1 1 
ATOM   8846  O OE2 . GLU D 1 68  ? -28.460 26.237  88.944  1.00 110.91 ? 143  GLU D OE2 1 
ATOM   8847  N N   . ILE D 1 69  ? -33.453 24.046  86.152  1.00 68.62  ? 144  ILE D N   1 
ATOM   8848  C CA  . ILE D 1 69  ? -33.714 22.614  86.042  1.00 63.75  ? 144  ILE D CA  1 
ATOM   8849  C C   . ILE D 1 69  ? -33.701 22.187  84.581  1.00 68.12  ? 144  ILE D C   1 
ATOM   8850  O O   . ILE D 1 69  ? -33.141 21.144  84.228  1.00 70.87  ? 144  ILE D O   1 
ATOM   8851  C CB  . ILE D 1 69  ? -35.048 22.251  86.720  1.00 61.23  ? 144  ILE D CB  1 
ATOM   8852  C CG1 . ILE D 1 69  ? -34.989 22.533  88.222  1.00 69.15  ? 144  ILE D CG1 1 
ATOM   8853  C CG2 . ILE D 1 69  ? -35.395 20.789  86.471  1.00 56.76  ? 144  ILE D CG2 1 
ATOM   8854  C CD1 . ILE D 1 69  ? -36.332 22.422  88.910  1.00 67.98  ? 144  ILE D CD1 1 
ATOM   8855  N N   . ILE D 1 70  ? -34.304 22.995  83.705  1.00 65.96  ? 145  ILE D N   1 
ATOM   8856  C CA  . ILE D 1 70  ? -34.339 22.662  82.284  1.00 74.13  ? 145  ILE D CA  1 
ATOM   8857  C C   . ILE D 1 70  ? -32.942 22.722  81.685  1.00 73.79  ? 145  ILE D C   1 
ATOM   8858  O O   . ILE D 1 70  ? -32.577 21.893  80.845  1.00 67.05  ? 145  ILE D O   1 
ATOM   8859  C CB  . ILE D 1 70  ? -35.316 23.590  81.538  1.00 72.55  ? 145  ILE D CB  1 
ATOM   8860  C CG1 . ILE D 1 70  ? -36.743 23.360  82.029  1.00 58.20  ? 145  ILE D CG1 1 
ATOM   8861  C CG2 . ILE D 1 70  ? -35.216 23.384  80.029  1.00 69.02  ? 145  ILE D CG2 1 
ATOM   8862  C CD1 . ILE D 1 70  ? -37.673 24.509  81.736  1.00 60.50  ? 145  ILE D CD1 1 
ATOM   8863  N N   . ARG D 1 71  ? -32.144 23.709  82.095  1.00 67.76  ? 146  ARG D N   1 
ATOM   8864  C CA  . ARG D 1 71  ? -30.763 23.775  81.626  1.00 72.09  ? 146  ARG D CA  1 
ATOM   8865  C C   . ARG D 1 71  ? -29.995 22.518  82.030  1.00 71.88  ? 146  ARG D C   1 
ATOM   8866  O O   . ARG D 1 71  ? -29.310 21.887  81.206  1.00 70.71  ? 146  ARG D O   1 
ATOM   8867  C CB  . ARG D 1 71  ? -30.093 25.037  82.174  1.00 53.48  ? 146  ARG D CB  1 
ATOM   8868  C CG  . ARG D 1 71  ? -30.648 26.328  81.570  1.00 70.70  ? 146  ARG D CG  1 
ATOM   8869  C CD  . ARG D 1 71  ? -29.935 27.574  82.084  1.00 67.34  ? 146  ARG D CD  1 
ATOM   8870  N NE  . ARG D 1 71  ? -30.408 28.008  83.395  1.00 91.03  ? 146  ARG D NE  1 
ATOM   8871  C CZ  . ARG D 1 71  ? -31.332 28.940  83.588  1.00 104.42 ? 146  ARG D CZ  1 
ATOM   8872  N NH1 . ARG D 1 71  ? -31.920 29.552  82.572  1.00 102.01 ? 146  ARG D NH1 1 
ATOM   8873  N NH2 . ARG D 1 71  ? -31.675 29.268  84.831  1.00 96.54  ? 146  ARG D NH2 1 
ATOM   8874  N N   . LYS D 1 72  ? -30.125 22.124  83.296  1.00 68.96  ? 147  LYS D N   1 
ATOM   8875  C CA  . LYS D 1 72  ? -29.470 20.908  83.761  1.00 73.51  ? 147  LYS D CA  1 
ATOM   8876  C C   . LYS D 1 72  ? -29.954 19.692  82.980  1.00 72.20  ? 147  LYS D C   1 
ATOM   8877  O O   . LYS D 1 72  ? -29.170 18.787  82.685  1.00 79.00  ? 147  LYS D O   1 
ATOM   8878  C CB  . LYS D 1 72  ? -29.719 20.720  85.256  1.00 63.37  ? 147  LYS D CB  1 
ATOM   8879  C CG  . LYS D 1 72  ? -28.866 19.650  85.903  1.00 76.77  ? 147  LYS D CG  1 
ATOM   8880  C CD  . LYS D 1 72  ? -27.395 20.000  85.767  1.00 113.10 ? 147  LYS D CD  1 
ATOM   8881  C CE  . LYS D 1 72  ? -26.501 18.818  86.086  1.00 112.18 ? 147  LYS D CE  1 
ATOM   8882  N NZ  . LYS D 1 72  ? -25.319 18.768  85.187  1.00 90.79  ? 147  LYS D NZ  1 
ATOM   8883  N N   . MET D 1 73  ? -31.244 19.655  82.636  1.00 76.62  ? 148  MET D N   1 
ATOM   8884  C CA  . MET D 1 73  ? -31.769 18.527  81.872  1.00 75.37  ? 148  MET D CA  1 
ATOM   8885  C C   . MET D 1 73  ? -31.210 18.507  80.455  1.00 76.54  ? 148  MET D C   1 
ATOM   8886  O O   . MET D 1 73  ? -30.974 17.432  79.893  1.00 73.03  ? 148  MET D O   1 
ATOM   8887  C CB  . MET D 1 73  ? -33.297 18.568  81.832  1.00 75.40  ? 148  MET D CB  1 
ATOM   8888  C CG  . MET D 1 73  ? -33.980 18.523  83.192  1.00 73.14  ? 148  MET D CG  1 
ATOM   8889  S SD  . MET D 1 73  ? -33.018 17.750  84.506  1.00 79.20  ? 148  MET D SD  1 
ATOM   8890  C CE  . MET D 1 73  ? -33.119 16.036  84.025  1.00 35.72  ? 148  MET D CE  1 
ATOM   8891  N N   . THR D 1 74  ? -31.022 19.683  79.847  1.00 83.87  ? 149  THR D N   1 
ATOM   8892  C CA  . THR D 1 74  ? -30.334 19.725  78.560  1.00 85.79  ? 149  THR D CA  1 
ATOM   8893  C C   . THR D 1 74  ? -28.949 19.111  78.678  1.00 85.18  ? 149  THR D C   1 
ATOM   8894  O O   . THR D 1 74  ? -28.522 18.351  77.801  1.00 89.78  ? 149  THR D O   1 
ATOM   8895  C CB  . THR D 1 74  ? -30.224 21.157  78.030  1.00 66.10  ? 149  THR D CB  1 
ATOM   8896  O OG1 . THR D 1 74  ? -29.300 21.903  78.833  1.00 100.35 ? 149  THR D OG1 1 
ATOM   8897  C CG2 . THR D 1 74  ? -31.572 21.848  78.015  1.00 51.34  ? 149  THR D CG2 1 
ATOM   8898  N N   . GLU D 1 75  ? -28.235 19.421  79.762  1.00 81.80  ? 150  GLU D N   1 
ATOM   8899  C CA  . GLU D 1 75  ? -26.937 18.777  79.954  1.00 81.91  ? 150  GLU D CA  1 
ATOM   8900  C C   . GLU D 1 75  ? -27.077 17.265  80.130  1.00 84.60  ? 150  GLU D C   1 
ATOM   8901  O O   . GLU D 1 75  ? -26.331 16.493  79.517  1.00 87.65  ? 150  GLU D O   1 
ATOM   8902  C CB  . GLU D 1 75  ? -26.190 19.392  81.135  1.00 86.50  ? 150  GLU D CB  1 
ATOM   8903  C CG  . GLU D 1 75  ? -26.354 20.888  81.271  1.00 95.47  ? 150  GLU D CG  1 
ATOM   8904  C CD  . GLU D 1 75  ? -25.865 21.390  82.608  1.00 110.38 ? 150  GLU D CD  1 
ATOM   8905  O OE1 . GLU D 1 75  ? -25.041 20.688  83.232  1.00 90.31  ? 150  GLU D OE1 1 
ATOM   8906  O OE2 . GLU D 1 75  ? -26.289 22.486  83.029  1.00 154.02 ? 150  GLU D OE2 1 
ATOM   8907  N N   . GLU D 1 76  ? -28.033 16.822  80.944  1.00 87.27  ? 151  GLU D N   1 
ATOM   8908  C CA  . GLU D 1 76  ? -28.215 15.399  81.239  1.00 81.82  ? 151  GLU D CA  1 
ATOM   8909  C C   . GLU D 1 76  ? -29.015 14.654  80.173  1.00 78.83  ? 151  GLU D C   1 
ATOM   8910  O O   . GLU D 1 76  ? -29.398 13.504  80.409  1.00 84.42  ? 151  GLU D O   1 
ATOM   8911  C CB  . GLU D 1 76  ? -28.904 15.214  82.597  1.00 94.46  ? 151  GLU D CB  1 
ATOM   8912  C CG  . GLU D 1 76  ? -28.373 16.085  83.718  1.00 87.72  ? 151  GLU D CG  1 
ATOM   8913  C CD  . GLU D 1 76  ? -26.894 15.890  83.960  1.00 102.25 ? 151  GLU D CD  1 
ATOM   8914  O OE1 . GLU D 1 76  ? -26.529 14.886  84.605  1.00 116.20 ? 151  GLU D OE1 1 
ATOM   8915  O OE2 . GLU D 1 76  ? -26.100 16.738  83.502  1.00 100.35 ? 151  GLU D OE2 1 
ATOM   8916  N N   . PHE D 1 77  ? -29.276 15.280  79.024  1.00 73.42  ? 152  PHE D N   1 
ATOM   8917  C CA  . PHE D 1 77  ? -30.116 14.655  78.007  1.00 77.74  ? 152  PHE D CA  1 
ATOM   8918  C C   . PHE D 1 77  ? -29.529 13.330  77.532  1.00 93.68  ? 152  PHE D C   1 
ATOM   8919  O O   . PHE D 1 77  ? -30.269 12.367  77.298  1.00 89.73  ? 152  PHE D O   1 
ATOM   8920  C CB  . PHE D 1 77  ? -30.313 15.623  76.840  1.00 71.73  ? 152  PHE D CB  1 
ATOM   8921  C CG  . PHE D 1 77  ? -31.642 15.489  76.149  1.00 83.20  ? 152  PHE D CG  1 
ATOM   8922  C CD1 . PHE D 1 77  ? -32.021 14.292  75.566  1.00 85.59  ? 152  PHE D CD1 1 
ATOM   8923  C CD2 . PHE D 1 77  ? -32.522 16.559  76.104  1.00 81.24  ? 152  PHE D CD2 1 
ATOM   8924  C CE1 . PHE D 1 77  ? -33.244 14.170  74.931  1.00 81.44  ? 152  PHE D CE1 1 
ATOM   8925  C CE2 . PHE D 1 77  ? -33.751 16.442  75.477  1.00 70.94  ? 152  PHE D CE2 1 
ATOM   8926  C CZ  . PHE D 1 77  ? -34.112 15.244  74.891  1.00 76.24  ? 152  PHE D CZ  1 
ATOM   8927  N N   . ASP D 1 78  ? -28.201 13.261  77.393  1.00 104.12 ? 153  ASP D N   1 
ATOM   8928  C CA  . ASP D 1 78  ? -27.509 12.051  76.933  1.00 97.83  ? 153  ASP D CA  1 
ATOM   8929  C C   . ASP D 1 78  ? -28.108 11.524  75.631  1.00 99.81  ? 153  ASP D C   1 
ATOM   8930  O O   . ASP D 1 78  ? -28.129 10.316  75.379  1.00 105.17 ? 153  ASP D O   1 
ATOM   8931  C CB  . ASP D 1 78  ? -27.515 10.962  78.010  1.00 89.87  ? 153  ASP D CB  1 
ATOM   8932  C CG  . ASP D 1 78  ? -26.457 9.903   77.771  1.00 100.62 ? 153  ASP D CG  1 
ATOM   8933  O OD1 . ASP D 1 78  ? -25.485 10.193  77.041  1.00 111.35 ? 153  ASP D OD1 1 
ATOM   8934  O OD2 . ASP D 1 78  ? -26.601 8.784   78.306  1.00 86.08  ? 153  ASP D OD2 1 
ATOM   8935  N N   . GLU D 1 79  ? -28.607 12.432  74.798  1.00 83.90  ? 154  GLU D N   1 
ATOM   8936  C CA  . GLU D 1 79  ? -29.199 12.034  73.533  1.00 71.53  ? 154  GLU D CA  1 
ATOM   8937  C C   . GLU D 1 79  ? -28.126 11.497  72.595  1.00 90.82  ? 154  GLU D C   1 
ATOM   8938  O O   . GLU D 1 79  ? -26.963 11.908  72.641  1.00 98.04  ? 154  GLU D O   1 
ATOM   8939  C CB  . GLU D 1 79  ? -29.926 13.216  72.885  1.00 83.05  ? 154  GLU D CB  1 
ATOM   8940  C CG  . GLU D 1 79  ? -29.061 14.074  71.967  1.00 83.32  ? 154  GLU D CG  1 
ATOM   8941  C CD  . GLU D 1 79  ? -28.095 14.966  72.725  1.00 83.85  ? 154  GLU D CD  1 
ATOM   8942  O OE1 . GLU D 1 79  ? -28.209 15.052  73.966  1.00 76.27  ? 154  GLU D OE1 1 
ATOM   8943  O OE2 . GLU D 1 79  ? -27.219 15.580  72.080  1.00 94.30  ? 154  GLU D OE2 1 
ATOM   8944  N N   . ASP D 1 80  ? -28.522 10.547  71.753  1.00 100.18 ? 155  ASP D N   1 
ATOM   8945  C CA  . ASP D 1 80  ? -27.647 10.053  70.703  1.00 94.38  ? 155  ASP D CA  1 
ATOM   8946  C C   . ASP D 1 80  ? -27.962 10.667  69.347  1.00 97.04  ? 155  ASP D C   1 
ATOM   8947  O O   . ASP D 1 80  ? -27.153 10.539  68.422  1.00 115.16 ? 155  ASP D O   1 
ATOM   8948  C CB  . ASP D 1 80  ? -27.734 8.525   70.610  1.00 87.16  ? 155  ASP D CB  1 
ATOM   8949  C CG  . ASP D 1 80  ? -29.077 8.047   70.108  1.00 104.26 ? 155  ASP D CG  1 
ATOM   8950  O OD1 . ASP D 1 80  ? -30.107 8.441   70.697  1.00 108.85 ? 155  ASP D OD1 1 
ATOM   8951  O OD2 . ASP D 1 80  ? -29.103 7.282   69.123  1.00 105.58 ? 155  ASP D OD2 1 
ATOM   8952  N N   . SER D 1 81  ? -29.104 11.334  69.214  1.00 89.04  ? 156  SER D N   1 
ATOM   8953  C CA  . SER D 1 81  ? -29.481 12.005  67.978  1.00 93.49  ? 156  SER D CA  1 
ATOM   8954  C C   . SER D 1 81  ? -30.494 13.091  68.319  1.00 91.20  ? 156  SER D C   1 
ATOM   8955  O O   . SER D 1 81  ? -30.912 13.238  69.471  1.00 94.65  ? 156  SER D O   1 
ATOM   8956  C CB  . SER D 1 81  ? -30.046 11.015  66.957  1.00 99.84  ? 156  SER D CB  1 
ATOM   8957  O OG  . SER D 1 81  ? -31.432 10.811  67.165  1.00 94.79  ? 156  SER D OG  1 
ATOM   8958  N N   . GLY D 1 82  ? -30.890 13.854  67.301  1.00 82.62  ? 157  GLY D N   1 
ATOM   8959  C CA  . GLY D 1 82  ? -31.888 14.887  67.500  1.00 91.20  ? 157  GLY D CA  1 
ATOM   8960  C C   . GLY D 1 82  ? -33.312 14.388  67.590  1.00 78.96  ? 157  GLY D C   1 
ATOM   8961  O O   . GLY D 1 82  ? -34.221 15.185  67.839  1.00 59.84  ? 157  GLY D O   1 
ATOM   8962  N N   . ASP D 1 83  ? -33.526 13.089  67.391  1.00 82.93  ? 158  ASP D N   1 
ATOM   8963  C CA  . ASP D 1 83  ? -34.868 12.529  67.456  1.00 81.69  ? 158  ASP D CA  1 
ATOM   8964  C C   . ASP D 1 83  ? -35.382 12.522  68.891  1.00 83.40  ? 158  ASP D C   1 
ATOM   8965  O O   . ASP D 1 83  ? -34.646 12.210  69.831  1.00 75.71  ? 158  ASP D O   1 
ATOM   8966  C CB  . ASP D 1 83  ? -34.875 11.104  66.896  1.00 75.67  ? 158  ASP D CB  1 
ATOM   8967  C CG  . ASP D 1 83  ? -34.563 11.054  65.411  1.00 93.31  ? 158  ASP D CG  1 
ATOM   8968  O OD1 . ASP D 1 83  ? -33.445 11.453  65.021  1.00 127.32 ? 158  ASP D OD1 1 
ATOM   8969  O OD2 . ASP D 1 83  ? -35.432 10.604  64.634  1.00 95.69  ? 158  ASP D OD2 1 
ATOM   8970  N N   . TYR D 1 84  ? -36.650 12.872  69.056  1.00 66.74  ? 159  TYR D N   1 
ATOM   8971  C CA  . TYR D 1 84  ? -37.348 12.750  70.324  1.00 62.80  ? 159  TYR D CA  1 
ATOM   8972  C C   . TYR D 1 84  ? -38.654 12.007  70.083  1.00 67.75  ? 159  TYR D C   1 
ATOM   8973  O O   . TYR D 1 84  ? -39.096 11.883  68.934  1.00 68.38  ? 159  TYR D O   1 
ATOM   8974  C CB  . TYR D 1 84  ? -37.601 14.121  70.978  1.00 57.94  ? 159  TYR D CB  1 
ATOM   8975  C CG  . TYR D 1 84  ? -38.184 15.204  70.099  1.00 56.03  ? 159  TYR D CG  1 
ATOM   8976  C CD1 . TYR D 1 84  ? -37.370 15.977  69.284  1.00 52.82  ? 159  TYR D CD1 1 
ATOM   8977  C CD2 . TYR D 1 84  ? -39.545 15.483  70.119  1.00 73.70  ? 159  TYR D CD2 1 
ATOM   8978  C CE1 . TYR D 1 84  ? -37.896 16.980  68.494  1.00 68.76  ? 159  TYR D CE1 1 
ATOM   8979  C CE2 . TYR D 1 84  ? -40.082 16.486  69.333  1.00 69.54  ? 159  TYR D CE2 1 
ATOM   8980  C CZ  . TYR D 1 84  ? -39.252 17.232  68.524  1.00 73.78  ? 159  TYR D CZ  1 
ATOM   8981  O OH  . TYR D 1 84  ? -39.784 18.229  67.738  1.00 72.53  ? 159  TYR D OH  1 
ATOM   8982  N N   . PRO D 1 85  ? -39.279 11.462  71.146  1.00 77.53  ? 160  PRO D N   1 
ATOM   8983  C CA  . PRO D 1 85  ? -40.442 10.572  70.952  1.00 66.66  ? 160  PRO D CA  1 
ATOM   8984  C C   . PRO D 1 85  ? -41.535 11.109  70.041  1.00 68.15  ? 160  PRO D C   1 
ATOM   8985  O O   . PRO D 1 85  ? -42.117 10.334  69.272  1.00 62.06  ? 160  PRO D O   1 
ATOM   8986  C CB  . PRO D 1 85  ? -40.952 10.380  72.384  1.00 53.07  ? 160  PRO D CB  1 
ATOM   8987  C CG  . PRO D 1 85  ? -39.721 10.420  73.201  1.00 65.80  ? 160  PRO D CG  1 
ATOM   8988  C CD  . PRO D 1 85  ? -38.841 11.467  72.555  1.00 71.74  ? 160  PRO D CD  1 
ATOM   8989  N N   . LEU D 1 86  ? -41.833 12.408  70.102  1.00 65.82  ? 161  LEU D N   1 
ATOM   8990  C CA  . LEU D 1 86  ? -42.892 12.951  69.257  1.00 64.66  ? 161  LEU D CA  1 
ATOM   8991  C C   . LEU D 1 86  ? -42.489 12.942  67.788  1.00 59.07  ? 161  LEU D C   1 
ATOM   8992  O O   . LEU D 1 86  ? -43.332 12.719  66.911  1.00 70.94  ? 161  LEU D O   1 
ATOM   8993  C CB  . LEU D 1 86  ? -43.259 14.363  69.710  1.00 74.56  ? 161  LEU D CB  1 
ATOM   8994  C CG  . LEU D 1 86  ? -44.082 14.458  70.997  1.00 79.21  ? 161  LEU D CG  1 
ATOM   8995  C CD1 . LEU D 1 86  ? -44.822 15.783  71.055  1.00 72.52  ? 161  LEU D CD1 1 
ATOM   8996  C CD2 . LEU D 1 86  ? -45.057 13.291  71.110  1.00 66.73  ? 161  LEU D CD2 1 
ATOM   8997  N N   . THR D 1 87  ? -41.208 13.176  67.499  1.00 74.11  ? 162  THR D N   1 
ATOM   8998  C CA  . THR D 1 87  ? -40.727 13.121  66.123  1.00 63.90  ? 162  THR D CA  1 
ATOM   8999  C C   . THR D 1 87  ? -40.454 11.694  65.668  1.00 62.32  ? 162  THR D C   1 
ATOM   9000  O O   . THR D 1 87  ? -40.510 11.412  64.466  1.00 79.67  ? 162  THR D O   1 
ATOM   9001  C CB  . THR D 1 87  ? -39.452 13.953  65.967  1.00 66.53  ? 162  THR D CB  1 
ATOM   9002  O OG1 . THR D 1 87  ? -38.646 13.827  67.147  1.00 73.82  ? 162  THR D OG1 1 
ATOM   9003  C CG2 . THR D 1 87  ? -39.790 15.416  65.728  1.00 69.26  ? 162  THR D CG2 1 
ATOM   9004  N N   . MET D 1 88  ? -40.151 10.793  66.602  1.00 72.12  ? 163  MET D N   1 
ATOM   9005  C CA  . MET D 1 88  ? -39.809 9.421   66.250  1.00 72.77  ? 163  MET D CA  1 
ATOM   9006  C C   . MET D 1 88  ? -40.983 8.732   65.567  1.00 63.01  ? 163  MET D C   1 
ATOM   9007  O O   . MET D 1 88  ? -42.121 8.801   66.042  1.00 60.07  ? 163  MET D O   1 
ATOM   9008  C CB  . MET D 1 88  ? -39.398 8.647   67.502  1.00 63.83  ? 163  MET D CB  1 
ATOM   9009  C CG  . MET D 1 88  ? -37.977 8.915   67.961  1.00 59.38  ? 163  MET D CG  1 
ATOM   9010  S SD  . MET D 1 88  ? -37.538 7.982   69.439  1.00 91.66  ? 163  MET D SD  1 
ATOM   9011  C CE  . MET D 1 88  ? -36.452 9.145   70.262  1.00 72.32  ? 163  MET D CE  1 
ATOM   9012  N N   . ALA D 1 89  ? -40.705 8.072   64.449  1.00 63.79  ? 164  ALA D N   1 
ATOM   9013  C CA  . ALA D 1 89  ? -41.727 7.355   63.707  1.00 59.29  ? 164  ALA D CA  1 
ATOM   9014  C C   . ALA D 1 89  ? -41.820 5.911   64.189  1.00 66.12  ? 164  ALA D C   1 
ATOM   9015  O O   . ALA D 1 89  ? -40.956 5.407   64.909  1.00 76.53  ? 164  ALA D O   1 
ATOM   9016  C CB  . ALA D 1 89  ? -41.437 7.399   62.208  1.00 58.83  ? 164  ALA D CB  1 
ATOM   9017  N N   . GLY D 1 90  ? -42.893 5.241   63.778  1.00 75.31  ? 165  GLY D N   1 
ATOM   9018  C CA  . GLY D 1 90  ? -43.125 3.872   64.168  1.00 94.68  ? 165  GLY D CA  1 
ATOM   9019  C C   . GLY D 1 90  ? -44.418 3.709   64.941  1.00 103.16 ? 165  GLY D C   1 
ATOM   9020  O O   . GLY D 1 90  ? -44.921 4.650   65.563  1.00 98.74  ? 165  GLY D O   1 
ATOM   9021  N N   . PRO D 1 91  ? -44.982 2.497   64.915  1.00 100.65 ? 166  PRO D N   1 
ATOM   9022  C CA  . PRO D 1 91  ? -46.285 2.284   65.572  1.00 108.59 ? 166  PRO D CA  1 
ATOM   9023  C C   . PRO D 1 91  ? -46.251 2.519   67.071  1.00 104.79 ? 166  PRO D C   1 
ATOM   9024  O O   . PRO D 1 91  ? -47.169 3.145   67.625  1.00 109.76 ? 166  PRO D O   1 
ATOM   9025  C CB  . PRO D 1 91  ? -46.603 0.819   65.235  1.00 103.46 ? 166  PRO D CB  1 
ATOM   9026  C CG  . PRO D 1 91  ? -45.797 0.527   64.004  1.00 109.30 ? 166  PRO D CG  1 
ATOM   9027  C CD  . PRO D 1 91  ? -44.526 1.300   64.189  1.00 104.49 ? 166  PRO D CD  1 
ATOM   9028  N N   . GLN D 1 92  ? -45.207 2.023   67.740  1.00 91.93  ? 167  GLN D N   1 
ATOM   9029  C CA  . GLN D 1 92  ? -45.095 2.186   69.185  1.00 103.65 ? 167  GLN D CA  1 
ATOM   9030  C C   . GLN D 1 92  ? -45.127 3.659   69.572  1.00 98.60  ? 167  GLN D C   1 
ATOM   9031  O O   . GLN D 1 92  ? -45.766 4.039   70.559  1.00 105.80 ? 167  GLN D O   1 
ATOM   9032  C CB  . GLN D 1 92  ? -43.810 1.520   69.678  1.00 90.32  ? 167  GLN D CB  1 
ATOM   9033  C CG  . GLN D 1 92  ? -43.561 1.626   71.172  1.00 97.24  ? 167  GLN D CG  1 
ATOM   9034  C CD  . GLN D 1 92  ? -42.086 1.543   71.512  1.00 111.20 ? 167  GLN D CD  1 
ATOM   9035  O OE1 . GLN D 1 92  ? -41.235 1.526   70.622  1.00 116.76 ? 167  GLN D OE1 1 
ATOM   9036  N NE2 . GLN D 1 92  ? -41.777 1.458   72.798  1.00 135.76 ? 167  GLN D NE2 1 
ATOM   9037  N N   . TRP D 1 93  ? -44.483 4.513   68.775  1.00 86.16  ? 168  TRP D N   1 
ATOM   9038  C CA  . TRP D 1 93  ? -44.423 5.929   69.112  1.00 76.61  ? 168  TRP D CA  1 
ATOM   9039  C C   . TRP D 1 93  ? -45.733 6.648   68.808  1.00 90.48  ? 168  TRP D C   1 
ATOM   9040  O O   . TRP D 1 93  ? -46.082 7.610   69.503  1.00 93.31  ? 168  TRP D O   1 
ATOM   9041  C CB  . TRP D 1 93  ? -43.250 6.577   68.380  1.00 88.45  ? 168  TRP D CB  1 
ATOM   9042  C CG  . TRP D 1 93  ? -41.917 6.196   68.971  1.00 80.81  ? 168  TRP D CG  1 
ATOM   9043  C CD1 . TRP D 1 93  ? -40.862 5.638   68.312  1.00 68.86  ? 168  TRP D CD1 1 
ATOM   9044  C CD2 . TRP D 1 93  ? -41.499 6.350   70.337  1.00 78.95  ? 168  TRP D CD2 1 
ATOM   9045  N NE1 . TRP D 1 93  ? -39.817 5.429   69.180  1.00 77.59  ? 168  TRP D NE1 1 
ATOM   9046  C CE2 . TRP D 1 93  ? -40.182 5.860   70.428  1.00 76.76  ? 168  TRP D CE2 1 
ATOM   9047  C CE3 . TRP D 1 93  ? -42.110 6.855   71.490  1.00 86.89  ? 168  TRP D CE3 1 
ATOM   9048  C CZ2 . TRP D 1 93  ? -39.466 5.857   71.625  1.00 79.40  ? 168  TRP D CZ2 1 
ATOM   9049  C CZ3 . TRP D 1 93  ? -41.398 6.851   72.678  1.00 67.95  ? 168  TRP D CZ3 1 
ATOM   9050  C CH2 . TRP D 1 93  ? -40.091 6.356   72.735  1.00 73.58  ? 168  TRP D CH2 1 
ATOM   9051  N N   . LYS D 1 94  ? -46.479 6.193   67.798  1.00 91.85  ? 169  LYS D N   1 
ATOM   9052  C CA  . LYS D 1 94  ? -47.823 6.719   67.574  1.00 90.19  ? 169  LYS D CA  1 
ATOM   9053  C C   . LYS D 1 94  ? -48.731 6.400   68.759  1.00 76.22  ? 169  LYS D C   1 
ATOM   9054  O O   . LYS D 1 94  ? -49.438 7.279   69.284  1.00 77.01  ? 169  LYS D O   1 
ATOM   9055  C CB  . LYS D 1 94  ? -48.390 6.145   66.272  1.00 87.06  ? 169  LYS D CB  1 
ATOM   9056  C CG  . LYS D 1 94  ? -49.838 6.512   65.980  1.00 114.53 ? 169  LYS D CG  1 
ATOM   9057  C CD  . LYS D 1 94  ? -50.631 5.323   65.437  1.00 132.53 ? 169  LYS D CD  1 
ATOM   9058  C CE  . LYS D 1 94  ? -51.101 4.396   66.550  1.00 141.43 ? 169  LYS D CE  1 
ATOM   9059  N NZ  . LYS D 1 94  ? -51.604 3.102   66.009  1.00 138.32 ? 169  LYS D NZ  1 
ATOM   9060  N N   . LYS D 1 95  ? -48.715 5.135   69.194  1.00 77.46  ? 170  LYS D N   1 
ATOM   9061  C CA  . LYS D 1 95  ? -49.463 4.752   70.387  1.00 84.87  ? 170  LYS D CA  1 
ATOM   9062  C C   . LYS D 1 95  ? -49.019 5.570   71.594  1.00 81.07  ? 170  LYS D C   1 
ATOM   9063  O O   . LYS D 1 95  ? -49.842 5.945   72.437  1.00 94.60  ? 170  LYS D O   1 
ATOM   9064  C CB  . LYS D 1 95  ? -49.295 3.254   70.650  1.00 87.07  ? 170  LYS D CB  1 
ATOM   9065  C CG  . LYS D 1 95  ? -49.851 2.772   71.984  1.00 106.57 ? 170  LYS D CG  1 
ATOM   9066  C CD  . LYS D 1 95  ? -48.751 2.534   73.010  1.00 123.40 ? 170  LYS D CD  1 
ATOM   9067  C CE  . LYS D 1 95  ? -49.337 2.284   74.391  1.00 132.10 ? 170  LYS D CE  1 
ATOM   9068  N NZ  . LYS D 1 95  ? -48.298 2.329   75.455  1.00 134.01 ? 170  LYS D NZ  1 
ATOM   9069  N N   . PHE D 1 96  ? -47.719 5.870   71.685  1.00 82.29  ? 171  PHE D N   1 
ATOM   9070  C CA  . PHE D 1 96  ? -47.219 6.675   72.796  1.00 74.52  ? 171  PHE D CA  1 
ATOM   9071  C C   . PHE D 1 96  ? -47.767 8.094   72.760  1.00 76.66  ? 171  PHE D C   1 
ATOM   9072  O O   . PHE D 1 96  ? -48.106 8.657   73.805  1.00 83.74  ? 171  PHE D O   1 
ATOM   9073  C CB  . PHE D 1 96  ? -45.694 6.721   72.786  1.00 63.43  ? 171  PHE D CB  1 
ATOM   9074  C CG  . PHE D 1 96  ? -45.133 7.859   73.588  1.00 56.77  ? 171  PHE D CG  1 
ATOM   9075  C CD1 . PHE D 1 96  ? -45.091 7.789   74.970  1.00 65.27  ? 171  PHE D CD1 1 
ATOM   9076  C CD2 . PHE D 1 96  ? -44.669 9.008   72.964  1.00 53.57  ? 171  PHE D CD2 1 
ATOM   9077  C CE1 . PHE D 1 96  ? -44.587 8.835   75.718  1.00 64.50  ? 171  PHE D CE1 1 
ATOM   9078  C CE2 . PHE D 1 96  ? -44.164 10.059  73.706  1.00 59.70  ? 171  PHE D CE2 1 
ATOM   9079  C CZ  . PHE D 1 96  ? -44.121 9.972   75.086  1.00 67.76  ? 171  PHE D CZ  1 
ATOM   9080  N N   . LYS D 1 97  ? -47.801 8.712   71.579  1.00 72.12  ? 172  LYS D N   1 
ATOM   9081  C CA  . LYS D 1 97  ? -48.376 10.050  71.456  1.00 63.44  ? 172  LYS D CA  1 
ATOM   9082  C C   . LYS D 1 97  ? -49.822 10.064  71.939  1.00 72.47  ? 172  LYS D C   1 
ATOM   9083  O O   . LYS D 1 97  ? -50.220 10.911  72.763  1.00 80.59  ? 172  LYS D O   1 
ATOM   9084  C CB  . LYS D 1 97  ? -48.284 10.520  70.003  1.00 77.30  ? 172  LYS D CB  1 
ATOM   9085  C CG  . LYS D 1 97  ? -48.683 11.969  69.770  1.00 57.30  ? 172  LYS D CG  1 
ATOM   9086  C CD  . LYS D 1 97  ? -47.977 12.552  68.551  1.00 72.76  ? 172  LYS D CD  1 
ATOM   9087  C CE  . LYS D 1 97  ? -48.023 14.075  68.553  1.00 93.55  ? 172  LYS D CE  1 
ATOM   9088  N NZ  . LYS D 1 97  ? -49.390 14.603  68.279  1.00 95.62  ? 172  LYS D NZ  1 
ATOM   9089  N N   . SER D 1 98  ? -50.624 9.119   71.434  1.00 86.34  ? 173  SER D N   1 
ATOM   9090  C CA  . SER D 1 98  ? -52.025 9.057   71.846  1.00 83.89  ? 173  SER D CA  1 
ATOM   9091  C C   . SER D 1 98  ? -52.150 8.840   73.352  1.00 79.71  ? 173  SER D C   1 
ATOM   9092  O O   . SER D 1 98  ? -52.969 9.491   74.015  1.00 78.22  ? 173  SER D O   1 
ATOM   9093  C CB  . SER D 1 98  ? -52.759 7.958   71.076  1.00 85.57  ? 173  SER D CB  1 
ATOM   9094  O OG  . SER D 1 98  ? -52.008 6.757   71.040  1.00 93.58  ? 173  SER D OG  1 
ATOM   9095  N N   . SER D 1 99  ? -51.330 7.944   73.914  1.00 69.35  ? 174  SER D N   1 
ATOM   9096  C CA  . SER D 1 99  ? -51.407 7.663   75.344  1.00 61.13  ? 174  SER D CA  1 
ATOM   9097  C C   . SER D 1 99  ? -50.940 8.847   76.179  1.00 64.61  ? 174  SER D C   1 
ATOM   9098  O O   . SER D 1 99  ? -51.434 9.047   77.288  1.00 70.47  ? 174  SER D O   1 
ATOM   9099  C CB  . SER D 1 99  ? -50.584 6.420   75.680  1.00 66.82  ? 174  SER D CB  1 
ATOM   9100  O OG  . SER D 1 99  ? -50.802 5.398   74.724  1.00 84.37  ? 174  SER D OG  1 
ATOM   9101  N N   . PHE D 1 100 ? -50.004 9.641   75.663  1.00 63.01  ? 175  PHE D N   1 
ATOM   9102  C CA  . PHE D 1 100 ? -49.546 10.838  76.362  1.00 61.66  ? 175  PHE D CA  1 
ATOM   9103  C C   . PHE D 1 100 ? -50.680 11.850  76.493  1.00 58.06  ? 175  PHE D C   1 
ATOM   9104  O O   . PHE D 1 100 ? -50.991 12.335  77.598  1.00 63.23  ? 175  PHE D O   1 
ATOM   9105  C CB  . PHE D 1 100 ? -48.358 11.416  75.586  1.00 54.46  ? 175  PHE D CB  1 
ATOM   9106  C CG  . PHE D 1 100 ? -47.800 12.692  76.143  1.00 57.05  ? 175  PHE D CG  1 
ATOM   9107  C CD1 . PHE D 1 100 ? -47.236 12.731  77.407  1.00 63.84  ? 175  PHE D CD1 1 
ATOM   9108  C CD2 . PHE D 1 100 ? -47.807 13.848  75.381  1.00 50.68  ? 175  PHE D CD2 1 
ATOM   9109  C CE1 . PHE D 1 100 ? -46.706 13.907  77.907  1.00 59.73  ? 175  PHE D CE1 1 
ATOM   9110  C CE2 . PHE D 1 100 ? -47.282 15.026  75.875  1.00 50.41  ? 175  PHE D CE2 1 
ATOM   9111  C CZ  . PHE D 1 100 ? -46.730 15.055  77.140  1.00 51.76  ? 175  PHE D CZ  1 
ATOM   9112  N N   . CYS D 1 101 ? -51.327 12.161  75.366  1.00 45.70  ? 176  CYS D N   1 
ATOM   9113  C CA  . CYS D 1 101 ? -52.472 13.070  75.408  1.00 62.00  ? 176  CYS D CA  1 
ATOM   9114  C C   . CYS D 1 101 ? -53.572 12.532  76.324  1.00 65.91  ? 176  CYS D C   1 
ATOM   9115  O O   . CYS D 1 101 ? -54.141 13.272  77.148  1.00 62.99  ? 176  CYS D O   1 
ATOM   9116  C CB  . CYS D 1 101 ? -53.008 13.299  73.994  1.00 61.15  ? 176  CYS D CB  1 
ATOM   9117  S SG  . CYS D 1 101 ? -51.786 13.957  72.832  1.00 57.12  ? 176  CYS D SG  1 
ATOM   9118  N N   . GLU D 1 102 ? -53.876 11.236  76.203  1.00 62.08  ? 177  GLU D N   1 
ATOM   9119  C CA  . GLU D 1 102 ? -54.925 10.643  77.024  1.00 60.22  ? 177  GLU D CA  1 
ATOM   9120  C C   . GLU D 1 102 ? -54.563 10.685  78.503  1.00 57.50  ? 177  GLU D C   1 
ATOM   9121  O O   . GLU D 1 102 ? -55.434 10.892  79.352  1.00 72.45  ? 177  GLU D O   1 
ATOM   9122  C CB  . GLU D 1 102 ? -55.191 9.206   76.576  1.00 65.19  ? 177  GLU D CB  1 
ATOM   9123  C CG  . GLU D 1 102 ? -56.184 8.465   77.456  1.00 84.93  ? 177  GLU D CG  1 
ATOM   9124  C CD  . GLU D 1 102 ? -56.164 6.966   77.234  1.00 97.92  ? 177  GLU D CD  1 
ATOM   9125  O OE1 . GLU D 1 102 ? -55.307 6.490   76.460  1.00 107.58 ? 177  GLU D OE1 1 
ATOM   9126  O OE2 . GLU D 1 102 ? -57.002 6.264   77.837  1.00 89.32  ? 177  GLU D OE2 1 
ATOM   9127  N N   . PHE D 1 103 ? -53.287 10.475  78.832  1.00 59.39  ? 178  PHE D N   1 
ATOM   9128  C CA  . PHE D 1 103 ? -52.837 10.598  80.213  1.00 63.35  ? 178  PHE D CA  1 
ATOM   9129  C C   . PHE D 1 103 ? -53.141 11.976  80.766  1.00 64.87  ? 178  PHE D C   1 
ATOM   9130  O O   . PHE D 1 103 ? -53.663 12.109  81.879  1.00 68.37  ? 178  PHE D O   1 
ATOM   9131  C CB  . PHE D 1 103 ? -51.338 10.317  80.307  1.00 59.63  ? 178  PHE D CB  1 
ATOM   9132  C CG  . PHE D 1 103 ? -50.794 10.423  81.703  1.00 54.57  ? 178  PHE D CG  1 
ATOM   9133  C CD1 . PHE D 1 103 ? -50.915 9.374   82.596  1.00 56.90  ? 178  PHE D CD1 1 
ATOM   9134  C CD2 . PHE D 1 103 ? -50.167 11.587  82.126  1.00 50.07  ? 178  PHE D CD2 1 
ATOM   9135  C CE1 . PHE D 1 103 ? -50.413 9.478   83.879  1.00 60.85  ? 178  PHE D CE1 1 
ATOM   9136  C CE2 . PHE D 1 103 ? -49.667 11.698  83.406  1.00 46.66  ? 178  PHE D CE2 1 
ATOM   9137  C CZ  . PHE D 1 103 ? -49.790 10.642  84.284  1.00 66.17  ? 178  PHE D CZ  1 
ATOM   9138  N N   . ILE D 1 104 ? -52.789 13.020  80.013  1.00 64.18  ? 179  ILE D N   1 
ATOM   9139  C CA  . ILE D 1 104 ? -53.080 14.373  80.486  1.00 58.80  ? 179  ILE D CA  1 
ATOM   9140  C C   . ILE D 1 104 ? -54.575 14.534  80.750  1.00 57.09  ? 179  ILE D C   1 
ATOM   9141  O O   . ILE D 1 104 ? -54.996 15.000  81.825  1.00 58.76  ? 179  ILE D O   1 
ATOM   9142  C CB  . ILE D 1 104 ? -52.565 15.415  79.480  1.00 50.06  ? 179  ILE D CB  1 
ATOM   9143  C CG1 . ILE D 1 104 ? -51.074 15.194  79.231  1.00 57.81  ? 179  ILE D CG1 1 
ATOM   9144  C CG2 . ILE D 1 104 ? -52.824 16.818  79.996  1.00 41.83  ? 179  ILE D CG2 1 
ATOM   9145  C CD1 . ILE D 1 104 ? -50.603 15.663  77.883  1.00 54.98  ? 179  ILE D CD1 1 
ATOM   9146  N N   . GLY D 1 105 ? -55.399 14.125  79.781  1.00 50.17  ? 180  GLY D N   1 
ATOM   9147  C CA  . GLY D 1 105 ? -56.839 14.288  79.937  1.00 62.43  ? 180  GLY D CA  1 
ATOM   9148  C C   . GLY D 1 105 ? -57.392 13.549  81.143  1.00 67.53  ? 180  GLY D C   1 
ATOM   9149  O O   . GLY D 1 105 ? -58.191 14.092  81.917  1.00 58.90  ? 180  GLY D O   1 
ATOM   9150  N N   . VAL D 1 106 ? -56.967 12.295  81.320  1.00 66.92  ? 181  VAL D N   1 
ATOM   9151  C CA  . VAL D 1 106 ? -57.459 11.471  82.419  1.00 61.03  ? 181  VAL D CA  1 
ATOM   9152  C C   . VAL D 1 106 ? -57.006 12.032  83.757  1.00 59.18  ? 181  VAL D C   1 
ATOM   9153  O O   . VAL D 1 106 ? -57.768 12.036  84.729  1.00 69.47  ? 181  VAL D O   1 
ATOM   9154  C CB  . VAL D 1 106 ? -57.004 10.011  82.246  1.00 57.09  ? 181  VAL D CB  1 
ATOM   9155  C CG1 . VAL D 1 106 ? -57.472 9.176   83.419  1.00 70.68  ? 181  VAL D CG1 1 
ATOM   9156  C CG2 . VAL D 1 106 ? -57.547 9.429   80.958  1.00 67.96  ? 181  VAL D CG2 1 
ATOM   9157  N N   . LEU D 1 107 ? -55.758 12.497  83.841  1.00 63.12  ? 182  LEU D N   1 
ATOM   9158  C CA  . LEU D 1 107 ? -55.286 13.108  85.077  1.00 66.42  ? 182  LEU D CA  1 
ATOM   9159  C C   . LEU D 1 107 ? -56.181 14.275  85.471  1.00 66.02  ? 182  LEU D C   1 
ATOM   9160  O O   . LEU D 1 107 ? -56.642 14.366  86.621  1.00 65.66  ? 182  LEU D O   1 
ATOM   9161  C CB  . LEU D 1 107 ? -53.837 13.564  84.912  1.00 55.08  ? 182  LEU D CB  1 
ATOM   9162  C CG  . LEU D 1 107 ? -53.142 14.118  86.154  1.00 53.85  ? 182  LEU D CG  1 
ATOM   9163  C CD1 . LEU D 1 107 ? -52.830 13.005  87.146  1.00 71.90  ? 182  LEU D CD1 1 
ATOM   9164  C CD2 . LEU D 1 107 ? -51.879 14.863  85.761  1.00 59.60  ? 182  LEU D CD2 1 
ATOM   9165  N N   . VAL D 1 108 ? -56.469 15.161  84.512  1.00 60.62  ? 183  VAL D N   1 
ATOM   9166  C CA  . VAL D 1 108 ? -57.322 16.306  84.825  1.00 52.61  ? 183  VAL D CA  1 
ATOM   9167  C C   . VAL D 1 108 ? -58.691 15.837  85.298  1.00 54.88  ? 183  VAL D C   1 
ATOM   9168  O O   . VAL D 1 108 ? -59.183 16.267  86.347  1.00 59.63  ? 183  VAL D O   1 
ATOM   9169  C CB  . VAL D 1 108 ? -57.443 17.246  83.617  1.00 64.51  ? 183  VAL D CB  1 
ATOM   9170  C CG1 . VAL D 1 108 ? -58.340 18.427  83.969  1.00 64.58  ? 183  VAL D CG1 1 
ATOM   9171  C CG2 . VAL D 1 108 ? -56.080 17.711  83.191  1.00 45.13  ? 183  VAL D CG2 1 
ATOM   9172  N N   . ARG D 1 109 ? -59.323 14.937  84.535  1.00 65.65  ? 184  ARG D N   1 
ATOM   9173  C CA  . ARG D 1 109 ? -60.670 14.491  84.896  1.00 60.44  ? 184  ARG D CA  1 
ATOM   9174  C C   . ARG D 1 109 ? -60.703 13.803  86.258  1.00 49.13  ? 184  ARG D C   1 
ATOM   9175  O O   . ARG D 1 109 ? -61.713 13.883  86.968  1.00 62.46  ? 184  ARG D O   1 
ATOM   9176  C CB  . ARG D 1 109 ? -61.233 13.560  83.818  1.00 57.70  ? 184  ARG D CB  1 
ATOM   9177  C CG  . ARG D 1 109 ? -61.708 14.269  82.558  1.00 84.76  ? 184  ARG D CG  1 
ATOM   9178  C CD  . ARG D 1 109 ? -61.790 13.303  81.385  1.00 80.45  ? 184  ARG D CD  1 
ATOM   9179  N NE  . ARG D 1 109 ? -61.998 11.933  81.841  1.00 99.04  ? 184  ARG D NE  1 
ATOM   9180  C CZ  . ARG D 1 109 ? -61.233 10.909  81.494  1.00 111.73 ? 184  ARG D CZ  1 
ATOM   9181  N NH1 . ARG D 1 109 ? -60.245 11.052  80.628  1.00 113.50 ? 184  ARG D NH1 1 
ATOM   9182  N NH2 . ARG D 1 109 ? -61.457 9.715   82.038  1.00 108.60 ? 184  ARG D NH2 1 
ATOM   9183  N N   . GLN D 1 110 ? -59.619 13.136  86.649  1.00 51.74  ? 185  GLN D N   1 
ATOM   9184  C CA  . GLN D 1 110 ? -59.605 12.459  87.942  1.00 61.45  ? 185  GLN D CA  1 
ATOM   9185  C C   . GLN D 1 110 ? -59.378 13.416  89.097  1.00 62.58  ? 185  GLN D C   1 
ATOM   9186  O O   . GLN D 1 110 ? -59.873 13.171  90.204  1.00 70.74  ? 185  GLN D O   1 
ATOM   9187  C CB  . GLN D 1 110 ? -58.551 11.355  87.936  1.00 75.67  ? 185  GLN D CB  1 
ATOM   9188  C CG  . GLN D 1 110 ? -58.955 10.304  86.977  1.00 80.78  ? 185  GLN D CG  1 
ATOM   9189  C CD  . GLN D 1 110 ? -60.332 9.826   87.323  1.00 65.15  ? 185  GLN D CD  1 
ATOM   9190  O OE1 . GLN D 1 110 ? -61.277 10.075  86.585  1.00 69.40  ? 185  GLN D OE1 1 
ATOM   9191  N NE2 . GLN D 1 110 ? -60.455 9.106   88.432  1.00 57.39  ? 185  GLN D NE2 1 
ATOM   9192  N N   . CYS D 1 111 ? -58.650 14.503  88.870  1.00 56.69  ? 186  CYS D N   1 
ATOM   9193  C CA  . CYS D 1 111 ? -58.489 15.496  89.918  1.00 59.30  ? 186  CYS D CA  1 
ATOM   9194  C C   . CYS D 1 111 ? -59.508 16.629  89.841  1.00 60.28  ? 186  CYS D C   1 
ATOM   9195  O O   . CYS D 1 111 ? -59.457 17.533  90.679  1.00 65.84  ? 186  CYS D O   1 
ATOM   9196  C CB  . CYS D 1 111 ? -57.068 16.067  89.885  1.00 60.38  ? 186  CYS D CB  1 
ATOM   9197  S SG  . CYS D 1 111 ? -55.770 14.837  89.592  1.00 66.16  ? 186  CYS D SG  1 
ATOM   9198  N N   . GLN D 1 112 ? -60.454 16.586  88.896  1.00 59.83  ? 187  GLN D N   1 
ATOM   9199  C CA  . GLN D 1 112 ? -61.273 17.758  88.584  1.00 61.84  ? 187  GLN D CA  1 
ATOM   9200  C C   . GLN D 1 112 ? -62.241 18.155  89.695  1.00 59.74  ? 187  GLN D C   1 
ATOM   9201  O O   . GLN D 1 112 ? -62.901 19.191  89.554  1.00 62.40  ? 187  GLN D O   1 
ATOM   9202  C CB  . GLN D 1 112 ? -62.075 17.535  87.299  1.00 60.18  ? 187  GLN D CB  1 
ATOM   9203  C CG  . GLN D 1 112 ? -63.313 16.668  87.475  1.00 53.34  ? 187  GLN D CG  1 
ATOM   9204  C CD  . GLN D 1 112 ? -63.989 16.335  86.156  1.00 62.25  ? 187  GLN D CD  1 
ATOM   9205  O OE1 . GLN D 1 112 ? -64.400 17.228  85.413  1.00 63.52  ? 187  GLN D OE1 1 
ATOM   9206  N NE2 . GLN D 1 112 ? -64.119 15.047  85.864  1.00 66.70  ? 187  GLN D NE2 1 
ATOM   9207  N N   . TYR D 1 113 ? -62.355 17.388  90.779  1.00 59.40  ? 188  TYR D N   1 
ATOM   9208  C CA  . TYR D 1 113 ? -63.299 17.706  91.842  1.00 54.22  ? 188  TYR D CA  1 
ATOM   9209  C C   . TYR D 1 113 ? -62.640 18.040  93.172  1.00 58.64  ? 188  TYR D C   1 
ATOM   9210  O O   . TYR D 1 113 ? -63.347 18.419  94.114  1.00 79.11  ? 188  TYR D O   1 
ATOM   9211  C CB  . TYR D 1 113 ? -64.282 16.545  92.050  1.00 61.46  ? 188  TYR D CB  1 
ATOM   9212  C CG  . TYR D 1 113 ? -65.154 16.254  90.851  1.00 64.19  ? 188  TYR D CG  1 
ATOM   9213  C CD1 . TYR D 1 113 ? -66.044 17.205  90.368  1.00 58.36  ? 188  TYR D CD1 1 
ATOM   9214  C CD2 . TYR D 1 113 ? -65.089 15.028  90.202  1.00 74.19  ? 188  TYR D CD2 1 
ATOM   9215  C CE1 . TYR D 1 113 ? -66.844 16.942  89.271  1.00 65.79  ? 188  TYR D CE1 1 
ATOM   9216  C CE2 . TYR D 1 113 ? -65.884 14.756  89.104  1.00 73.08  ? 188  TYR D CE2 1 
ATOM   9217  C CZ  . TYR D 1 113 ? -66.760 15.717  88.643  1.00 76.61  ? 188  TYR D CZ  1 
ATOM   9218  O OH  . TYR D 1 113 ? -67.553 15.449  87.551  1.00 90.70  ? 188  TYR D OH  1 
ATOM   9219  N N   . SER D 1 114 ? -61.319 17.922  93.283  1.00 63.84  ? 189  SER D N   1 
ATOM   9220  C CA  . SER D 1 114 ? -60.660 18.097  94.570  1.00 64.64  ? 189  SER D CA  1 
ATOM   9221  C C   . SER D 1 114 ? -59.210 18.528  94.404  1.00 70.83  ? 189  SER D C   1 
ATOM   9222  O O   . SER D 1 114 ? -58.852 19.670  94.711  1.00 67.54  ? 189  SER D O   1 
ATOM   9223  C CB  . SER D 1 114 ? -60.727 16.794  95.370  1.00 81.00  ? 189  SER D CB  1 
ATOM   9224  O OG  . SER D 1 114 ? -60.400 15.689  94.544  1.00 89.92  ? 189  SER D OG  1 
ATOM   9225  N N   . ILE D 1 115 ? -58.375 17.609  93.913  1.00 68.48  ? 190  ILE D N   1 
ATOM   9226  C CA  . ILE D 1 115 ? -56.943 17.864  93.807  1.00 70.80  ? 190  ILE D CA  1 
ATOM   9227  C C   . ILE D 1 115 ? -56.664 19.053  92.895  1.00 60.98  ? 190  ILE D C   1 
ATOM   9228  O O   . ILE D 1 115 ? -55.728 19.824  93.137  1.00 61.19  ? 190  ILE D O   1 
ATOM   9229  C CB  . ILE D 1 115 ? -56.227 16.587  93.326  1.00 69.00  ? 190  ILE D CB  1 
ATOM   9230  C CG1 . ILE D 1 115 ? -56.300 15.499  94.396  1.00 60.57  ? 190  ILE D CG1 1 
ATOM   9231  C CG2 . ILE D 1 115 ? -54.780 16.863  93.010  1.00 68.26  ? 190  ILE D CG2 1 
ATOM   9232  C CD1 . ILE D 1 115 ? -55.677 14.198  93.963  1.00 68.36  ? 190  ILE D CD1 1 
ATOM   9233  N N   . ILE D 1 116 ? -57.480 19.237  91.853  1.00 63.51  ? 191  ILE D N   1 
ATOM   9234  C CA  . ILE D 1 116 ? -57.303 20.366  90.941  1.00 64.39  ? 191  ILE D CA  1 
ATOM   9235  C C   . ILE D 1 116 ? -57.312 21.695  91.689  1.00 72.88  ? 191  ILE D C   1 
ATOM   9236  O O   . ILE D 1 116 ? -56.628 22.644  91.284  1.00 70.78  ? 191  ILE D O   1 
ATOM   9237  C CB  . ILE D 1 116 ? -58.379 20.325  89.834  1.00 52.58  ? 191  ILE D CB  1 
ATOM   9238  C CG1 . ILE D 1 116 ? -58.012 21.241  88.665  1.00 57.74  ? 191  ILE D CG1 1 
ATOM   9239  C CG2 . ILE D 1 116 ? -59.750 20.695  90.375  1.00 60.11  ? 191  ILE D CG2 1 
ATOM   9240  C CD1 . ILE D 1 116 ? -58.610 20.807  87.344  1.00 67.45  ? 191  ILE D CD1 1 
ATOM   9241  N N   . TYR D 1 117 ? -58.057 21.785  92.793  1.00 66.28  ? 192  TYR D N   1 
ATOM   9242  C CA  . TYR D 1 117 ? -58.168 23.015  93.564  1.00 67.74  ? 192  TYR D CA  1 
ATOM   9243  C C   . TYR D 1 117 ? -57.225 23.037  94.762  1.00 79.34  ? 192  TYR D C   1 
ATOM   9244  O O   . TYR D 1 117 ? -57.445 23.813  95.699  1.00 75.28  ? 192  TYR D O   1 
ATOM   9245  C CB  . TYR D 1 117 ? -59.612 23.226  94.029  1.00 56.19  ? 192  TYR D CB  1 
ATOM   9246  C CG  . TYR D 1 117 ? -60.647 23.110  92.929  1.00 51.49  ? 192  TYR D CG  1 
ATOM   9247  C CD1 . TYR D 1 117 ? -60.647 23.987  91.849  1.00 56.94  ? 192  TYR D CD1 1 
ATOM   9248  C CD2 . TYR D 1 117 ? -61.628 22.127  92.971  1.00 49.74  ? 192  TYR D CD2 1 
ATOM   9249  C CE1 . TYR D 1 117 ? -61.592 23.883  90.839  1.00 57.69  ? 192  TYR D CE1 1 
ATOM   9250  C CE2 . TYR D 1 117 ? -62.578 22.015  91.968  1.00 65.97  ? 192  TYR D CE2 1 
ATOM   9251  C CZ  . TYR D 1 117 ? -62.554 22.896  90.903  1.00 67.79  ? 192  TYR D CZ  1 
ATOM   9252  O OH  . TYR D 1 117 ? -63.493 22.792  89.899  1.00 59.20  ? 192  TYR D OH  1 
ATOM   9253  N N   . ASP D 1 118 ? -56.177 22.208  94.753  1.00 90.85  ? 193  ASP D N   1 
ATOM   9254  C CA  . ASP D 1 118 ? -55.263 22.135  95.889  1.00 76.67  ? 193  ASP D CA  1 
ATOM   9255  C C   . ASP D 1 118 ? -54.243 23.266  95.914  1.00 75.59  ? 193  ASP D C   1 
ATOM   9256  O O   . ASP D 1 118 ? -53.536 23.414  96.917  1.00 69.89  ? 193  ASP D O   1 
ATOM   9257  C CB  . ASP D 1 118 ? -54.534 20.786  95.890  1.00 54.07  ? 193  ASP D CB  1 
ATOM   9258  C CG  . ASP D 1 118 ? -53.483 20.685  94.799  1.00 86.61  ? 193  ASP D CG  1 
ATOM   9259  O OD1 . ASP D 1 118 ? -53.542 21.455  93.816  1.00 99.97  ? 193  ASP D OD1 1 
ATOM   9260  O OD2 . ASP D 1 118 ? -52.592 19.820  94.924  1.00 95.30  ? 193  ASP D OD2 1 
ATOM   9261  N N   . GLU D 1 119 ? -54.152 24.055  94.841  1.00 93.72  ? 194  GLU D N   1 
ATOM   9262  C CA  . GLU D 1 119 ? -53.150 25.115  94.712  1.00 96.83  ? 194  GLU D CA  1 
ATOM   9263  C C   . GLU D 1 119 ? -51.737 24.560  94.865  1.00 97.22  ? 194  GLU D C   1 
ATOM   9264  O O   . GLU D 1 119 ? -50.868 25.191  95.467  1.00 98.42  ? 194  GLU D O   1 
ATOM   9265  C CB  . GLU D 1 119 ? -53.389 26.245  95.715  1.00 95.59  ? 194  GLU D CB  1 
ATOM   9266  C CG  . GLU D 1 119 ? -54.585 27.113  95.403  1.00 116.11 ? 194  GLU D CG  1 
ATOM   9267  C CD  . GLU D 1 119 ? -55.765 26.782  96.289  1.00 127.53 ? 194  GLU D CD  1 
ATOM   9268  O OE1 . GLU D 1 119 ? -55.541 26.282  97.409  1.00 123.03 ? 194  GLU D OE1 1 
ATOM   9269  O OE2 . GLU D 1 119 ? -56.918 26.999  95.868  1.00 166.18 ? 194  GLU D OE2 1 
ATOM   9270  N N   . TYR D 1 120 ? -51.502 23.367  94.321  1.00 93.38  ? 195  TYR D N   1 
ATOM   9271  C CA  . TYR D 1 120 ? -50.180 22.763  94.427  1.00 79.24  ? 195  TYR D CA  1 
ATOM   9272  C C   . TYR D 1 120 ? -49.814 22.008  93.153  1.00 91.41  ? 195  TYR D C   1 
ATOM   9273  O O   . TYR D 1 120 ? -48.867 22.394  92.460  1.00 92.83  ? 195  TYR D O   1 
ATOM   9274  C CB  . TYR D 1 120 ? -50.104 21.837  95.645  1.00 89.55  ? 195  TYR D CB  1 
ATOM   9275  C CG  . TYR D 1 120 ? -48.694 21.416  96.007  1.00 96.58  ? 195  TYR D CG  1 
ATOM   9276  C CD1 . TYR D 1 120 ? -47.630 22.295  95.857  1.00 117.39 ? 195  TYR D CD1 1 
ATOM   9277  C CD2 . TYR D 1 120 ? -48.431 20.152  96.525  1.00 103.63 ? 195  TYR D CD2 1 
ATOM   9278  C CE1 . TYR D 1 120 ? -46.341 21.924  96.193  1.00 122.31 ? 195  TYR D CE1 1 
ATOM   9279  C CE2 . TYR D 1 120 ? -47.141 19.773  96.868  1.00 105.21 ? 195  TYR D CE2 1 
ATOM   9280  C CZ  . TYR D 1 120 ? -46.102 20.664  96.698  1.00 114.21 ? 195  TYR D CZ  1 
ATOM   9281  O OH  . TYR D 1 120 ? -44.818 20.298  97.032  1.00 114.20 ? 195  TYR D OH  1 
ATOM   9282  N N   . MET D 1 121 ? -50.556 20.944  92.820  1.00 84.53  ? 196  MET D N   1 
ATOM   9283  C CA  . MET D 1 121 ? -50.138 20.112  91.694  1.00 78.56  ? 196  MET D CA  1 
ATOM   9284  C C   . MET D 1 121 ? -50.505 20.744  90.355  1.00 71.17  ? 196  MET D C   1 
ATOM   9285  O O   . MET D 1 121 ? -49.726 20.654  89.403  1.00 82.90  ? 196  MET D O   1 
ATOM   9286  C CB  . MET D 1 121 ? -50.713 18.695  91.820  1.00 73.66  ? 196  MET D CB  1 
ATOM   9287  C CG  . MET D 1 121 ? -52.189 18.538  91.573  1.00 75.48  ? 196  MET D CG  1 
ATOM   9288  S SD  . MET D 1 121 ? -52.590 18.320  89.827  1.00 66.36  ? 196  MET D SD  1 
ATOM   9289  C CE  . MET D 1 121 ? -51.617 16.879  89.417  1.00 70.87  ? 196  MET D CE  1 
ATOM   9290  N N   . MET D 1 122 ? -51.672 21.385  90.249  1.00 66.18  ? 197  MET D N   1 
ATOM   9291  C CA  . MET D 1 122 ? -51.926 22.215  89.073  1.00 70.68  ? 197  MET D CA  1 
ATOM   9292  C C   . MET D 1 122 ? -50.871 23.301  88.926  1.00 74.21  ? 197  MET D C   1 
ATOM   9293  O O   . MET D 1 122 ? -50.293 23.483  87.849  1.00 76.34  ? 197  MET D O   1 
ATOM   9294  C CB  . MET D 1 122 ? -53.316 22.853  89.128  1.00 82.30  ? 197  MET D CB  1 
ATOM   9295  C CG  . MET D 1 122 ? -54.124 22.731  87.826  1.00 67.06  ? 197  MET D CG  1 
ATOM   9296  S SD  . MET D 1 122 ? -54.102 21.215  86.850  1.00 60.79  ? 197  MET D SD  1 
ATOM   9297  C CE  . MET D 1 122 ? -54.742 20.051  88.036  1.00 80.46  ? 197  MET D CE  1 
ATOM   9298  N N   . ASP D 1 123 ? -50.649 24.075  89.989  1.00 69.62  ? 198  ASP D N   1 
ATOM   9299  C CA  . ASP D 1 123 ? -49.631 25.119  89.956  1.00 65.95  ? 198  ASP D CA  1 
ATOM   9300  C C   . ASP D 1 123 ? -48.308 24.557  89.449  1.00 68.37  ? 198  ASP D C   1 
ATOM   9301  O O   . ASP D 1 123 ? -47.695 25.102  88.522  1.00 80.24  ? 198  ASP D O   1 
ATOM   9302  C CB  . ASP D 1 123 ? -49.483 25.725  91.353  1.00 89.83  ? 198  ASP D CB  1 
ATOM   9303  C CG  . ASP D 1 123 ? -48.568 26.933  91.378  1.00 85.46  ? 198  ASP D CG  1 
ATOM   9304  O OD1 . ASP D 1 123 ? -48.201 27.429  90.296  1.00 80.53  ? 198  ASP D OD1 1 
ATOM   9305  O OD2 . ASP D 1 123 ? -48.231 27.402  92.486  1.00 86.08  ? 198  ASP D OD2 1 
ATOM   9306  N N   . THR D 1 124 ? -47.880 23.433  90.028  1.00 62.96  ? 199  THR D N   1 
ATOM   9307  C CA  . THR D 1 124 ? -46.629 22.797  89.632  1.00 66.11  ? 199  THR D CA  1 
ATOM   9308  C C   . THR D 1 124 ? -46.640 22.417  88.154  1.00 56.30  ? 199  THR D C   1 
ATOM   9309  O O   . THR D 1 124 ? -45.669 22.665  87.428  1.00 73.64  ? 199  THR D O   1 
ATOM   9310  C CB  . THR D 1 124 ? -46.384 21.560  90.501  1.00 63.77  ? 199  THR D CB  1 
ATOM   9311  O OG1 . THR D 1 124 ? -46.140 21.962  91.855  1.00 75.24  ? 199  THR D OG1 1 
ATOM   9312  C CG2 . THR D 1 124 ? -45.193 20.769  89.988  1.00 61.76  ? 199  THR D CG2 1 
ATOM   9313  N N   . VAL D 1 125 ? -47.735 21.813  87.688  1.00 51.95  ? 200  VAL D N   1 
ATOM   9314  C CA  . VAL D 1 125 ? -47.764 21.276  86.330  1.00 51.87  ? 200  VAL D CA  1 
ATOM   9315  C C   . VAL D 1 125 ? -47.748 22.401  85.304  1.00 63.26  ? 200  VAL D C   1 
ATOM   9316  O O   . VAL D 1 125 ? -46.963 22.368  84.349  1.00 68.06  ? 200  VAL D O   1 
ATOM   9317  C CB  . VAL D 1 125 ? -48.976 20.348  86.136  1.00 54.57  ? 200  VAL D CB  1 
ATOM   9318  C CG1 . VAL D 1 125 ? -49.197 20.079  84.655  1.00 44.37  ? 200  VAL D CG1 1 
ATOM   9319  C CG2 . VAL D 1 125 ? -48.750 19.032  86.866  1.00 41.32  ? 200  VAL D CG2 1 
ATOM   9320  N N   . ILE D 1 126 ? -48.620 23.402  85.465  1.00 63.74  ? 201  ILE D N   1 
ATOM   9321  C CA  . ILE D 1 126 ? -48.598 24.518  84.516  1.00 64.04  ? 201  ILE D CA  1 
ATOM   9322  C C   . ILE D 1 126 ? -47.265 25.258  84.575  1.00 72.63  ? 201  ILE D C   1 
ATOM   9323  O O   . ILE D 1 126 ? -46.743 25.686  83.537  1.00 76.69  ? 201  ILE D O   1 
ATOM   9324  C CB  . ILE D 1 126 ? -49.798 25.479  84.701  1.00 58.82  ? 201  ILE D CB  1 
ATOM   9325  C CG1 . ILE D 1 126 ? -51.154 24.776  84.541  1.00 68.00  ? 201  ILE D CG1 1 
ATOM   9326  C CG2 . ILE D 1 126 ? -49.693 26.662  83.745  1.00 63.73  ? 201  ILE D CG2 1 
ATOM   9327  C CD1 . ILE D 1 126 ? -51.976 24.647  85.780  1.00 77.29  ? 201  ILE D CD1 1 
ATOM   9328  N N   . SER D 1 127 ? -46.671 25.391  85.766  1.00 64.60  ? 202  SER D N   1 
ATOM   9329  C CA  . SER D 1 127 ? -45.380 26.063  85.854  1.00 66.77  ? 202  SER D CA  1 
ATOM   9330  C C   . SER D 1 127 ? -44.315 25.322  85.052  1.00 76.75  ? 202  SER D C   1 
ATOM   9331  O O   . SER D 1 127 ? -43.616 25.918  84.220  1.00 73.95  ? 202  SER D O   1 
ATOM   9332  C CB  . SER D 1 127 ? -44.958 26.195  87.318  1.00 88.34  ? 202  SER D CB  1 
ATOM   9333  O OG  . SER D 1 127 ? -45.982 26.790  88.096  1.00 78.61  ? 202  SER D OG  1 
ATOM   9334  N N   . LEU D 1 128 ? -44.183 24.013  85.288  1.00 71.70  ? 203  LEU D N   1 
ATOM   9335  C CA  . LEU D 1 128 ? -43.191 23.220  84.567  1.00 64.61  ? 203  LEU D CA  1 
ATOM   9336  C C   . LEU D 1 128 ? -43.448 23.236  83.065  1.00 60.87  ? 203  LEU D C   1 
ATOM   9337  O O   . LEU D 1 128 ? -42.510 23.380  82.268  1.00 64.44  ? 203  LEU D O   1 
ATOM   9338  C CB  . LEU D 1 128 ? -43.194 21.786  85.092  1.00 51.84  ? 203  LEU D CB  1 
ATOM   9339  C CG  . LEU D 1 128 ? -42.478 20.756  84.218  1.00 52.07  ? 203  LEU D CG  1 
ATOM   9340  C CD1 . LEU D 1 128 ? -40.988 20.757  84.514  1.00 45.68  ? 203  LEU D CD1 1 
ATOM   9341  C CD2 . LEU D 1 128 ? -43.078 19.372  84.394  1.00 55.12  ? 203  LEU D CD2 1 
ATOM   9342  N N   . LEU D 1 129 ? -44.713 23.096  82.659  1.00 58.92  ? 204  LEU D N   1 
ATOM   9343  C CA  . LEU D 1 129 ? -45.027 23.032  81.236  1.00 64.13  ? 204  LEU D CA  1 
ATOM   9344  C C   . LEU D 1 129 ? -44.705 24.345  80.536  1.00 65.32  ? 204  LEU D C   1 
ATOM   9345  O O   . LEU D 1 129 ? -44.134 24.343  79.441  1.00 63.73  ? 204  LEU D O   1 
ATOM   9346  C CB  . LEU D 1 129 ? -46.495 22.662  81.025  1.00 58.10  ? 204  LEU D CB  1 
ATOM   9347  C CG  . LEU D 1 129 ? -46.918 21.234  81.373  1.00 60.86  ? 204  LEU D CG  1 
ATOM   9348  C CD1 . LEU D 1 129 ? -48.309 20.949  80.831  1.00 67.18  ? 204  LEU D CD1 1 
ATOM   9349  C CD2 . LEU D 1 129 ? -45.915 20.228  80.836  1.00 61.65  ? 204  LEU D CD2 1 
ATOM   9350  N N   . THR D 1 130 ? -45.062 25.479  81.147  1.00 64.60  ? 205  THR D N   1 
ATOM   9351  C CA  . THR D 1 130 ? -44.770 26.759  80.509  1.00 71.11  ? 205  THR D CA  1 
ATOM   9352  C C   . THR D 1 130 ? -43.270 27.039  80.498  1.00 75.57  ? 205  THR D C   1 
ATOM   9353  O O   . THR D 1 130 ? -42.743 27.601  79.523  1.00 76.15  ? 205  THR D O   1 
ATOM   9354  C CB  . THR D 1 130 ? -45.550 27.886  81.197  1.00 60.57  ? 205  THR D CB  1 
ATOM   9355  O OG1 . THR D 1 130 ? -45.487 29.070  80.394  1.00 80.89  ? 205  THR D OG1 1 
ATOM   9356  C CG2 . THR D 1 130 ? -45.005 28.190  82.583  1.00 80.49  ? 205  THR D CG2 1 
ATOM   9357  N N   . GLY D 1 131 ? -42.557 26.622  81.549  1.00 68.24  ? 206  GLY D N   1 
ATOM   9358  C CA  . GLY D 1 131 ? -41.111 26.750  81.527  1.00 68.32  ? 206  GLY D CA  1 
ATOM   9359  C C   . GLY D 1 131 ? -40.488 25.979  80.381  1.00 67.18  ? 206  GLY D C   1 
ATOM   9360  O O   . GLY D 1 131 ? -39.641 26.501  79.650  1.00 68.00  ? 206  GLY D O   1 
ATOM   9361  N N   . LEU D 1 132 ? -40.910 24.725  80.201  1.00 63.86  ? 207  LEU D N   1 
ATOM   9362  C CA  . LEU D 1 132 ? -40.406 23.936  79.082  1.00 55.51  ? 207  LEU D CA  1 
ATOM   9363  C C   . LEU D 1 132 ? -40.823 24.529  77.741  1.00 64.40  ? 207  LEU D C   1 
ATOM   9364  O O   . LEU D 1 132 ? -40.066 24.447  76.767  1.00 71.09  ? 207  LEU D O   1 
ATOM   9365  C CB  . LEU D 1 132 ? -40.887 22.490  79.191  1.00 57.91  ? 207  LEU D CB  1 
ATOM   9366  C CG  . LEU D 1 132 ? -40.426 21.642  80.373  1.00 65.75  ? 207  LEU D CG  1 
ATOM   9367  C CD1 . LEU D 1 132 ? -41.311 20.415  80.509  1.00 65.09  ? 207  LEU D CD1 1 
ATOM   9368  C CD2 . LEU D 1 132 ? -38.983 21.233  80.171  1.00 63.57  ? 207  LEU D CD2 1 
ATOM   9369  N N   . SER D 1 133 ? -42.018 25.124  77.670  1.00 63.32  ? 208  SER D N   1 
ATOM   9370  C CA  . SER D 1 133 ? -42.450 25.777  76.440  1.00 59.46  ? 208  SER D CA  1 
ATOM   9371  C C   . SER D 1 133 ? -41.578 26.980  76.108  1.00 72.34  ? 208  SER D C   1 
ATOM   9372  O O   . SER D 1 133 ? -41.475 27.362  74.937  1.00 79.49  ? 208  SER D O   1 
ATOM   9373  C CB  . SER D 1 133 ? -43.913 26.204  76.551  1.00 59.96  ? 208  SER D CB  1 
ATOM   9374  O OG  . SER D 1 133 ? -44.010 27.557  76.960  1.00 61.48  ? 208  SER D OG  1 
ATOM   9375  N N   . ASP D 1 134 ? -40.956 27.595  77.118  1.00 64.00  ? 209  ASP D N   1 
ATOM   9376  C CA  . ASP D 1 134 ? -40.005 28.668  76.847  1.00 68.48  ? 209  ASP D CA  1 
ATOM   9377  C C   . ASP D 1 134 ? -38.656 28.169  76.342  1.00 70.10  ? 209  ASP D C   1 
ATOM   9378  O O   . ASP D 1 134 ? -37.912 28.952  75.741  1.00 73.40  ? 209  ASP D O   1 
ATOM   9379  C CB  . ASP D 1 134 ? -39.784 29.522  78.098  1.00 63.06  ? 209  ASP D CB  1 
ATOM   9380  C CG  . ASP D 1 134 ? -39.321 30.929  77.766  1.00 74.49  ? 209  ASP D CG  1 
ATOM   9381  O OD1 . ASP D 1 134 ? -39.799 31.497  76.763  1.00 78.17  ? 209  ASP D OD1 1 
ATOM   9382  O OD2 . ASP D 1 134 ? -38.471 31.465  78.510  1.00 89.04  ? 209  ASP D OD2 1 
ATOM   9383  N N   . SER D 1 135 ? -38.325 26.899  76.562  1.00 58.07  ? 210  SER D N   1 
ATOM   9384  C CA  . SER D 1 135 ? -36.982 26.411  76.275  1.00 74.07  ? 210  SER D CA  1 
ATOM   9385  C C   . SER D 1 135 ? -36.688 26.421  74.779  1.00 71.53  ? 210  SER D C   1 
ATOM   9386  O O   . SER D 1 135 ? -37.574 26.190  73.951  1.00 60.29  ? 210  SER D O   1 
ATOM   9387  C CB  . SER D 1 135 ? -36.805 24.996  76.828  1.00 77.71  ? 210  SER D CB  1 
ATOM   9388  O OG  . SER D 1 135 ? -35.905 24.245  76.030  1.00 70.31  ? 210  SER D OG  1 
ATOM   9389  N N   . GLN D 1 136 ? -35.424 26.690  74.437  1.00 70.42  ? 211  GLN D N   1 
ATOM   9390  C CA  . GLN D 1 136 ? -34.985 26.624  73.048  1.00 70.74  ? 211  GLN D CA  1 
ATOM   9391  C C   . GLN D 1 136 ? -34.878 25.192  72.539  1.00 68.32  ? 211  GLN D C   1 
ATOM   9392  O O   . GLN D 1 136 ? -34.879 24.978  71.322  1.00 74.01  ? 211  GLN D O   1 
ATOM   9393  C CB  . GLN D 1 136 ? -33.635 27.324  72.881  1.00 82.17  ? 211  GLN D CB  1 
ATOM   9394  C CG  . GLN D 1 136 ? -33.584 28.773  73.332  1.00 86.34  ? 211  GLN D CG  1 
ATOM   9395  C CD  . GLN D 1 136 ? -32.995 29.677  72.264  1.00 82.95  ? 211  GLN D CD  1 
ATOM   9396  O OE1 . GLN D 1 136 ? -31.871 29.464  71.811  1.00 76.68  ? 211  GLN D OE1 1 
ATOM   9397  N NE2 . GLN D 1 136 ? -33.752 30.690  71.856  1.00 91.75  ? 211  GLN D NE2 1 
ATOM   9398  N N   . VAL D 1 137 ? -34.768 24.211  73.436  1.00 52.52  ? 212  VAL D N   1 
ATOM   9399  C CA  . VAL D 1 137 ? -34.695 22.816  73.017  1.00 61.72  ? 212  VAL D CA  1 
ATOM   9400  C C   . VAL D 1 137 ? -36.011 22.427  72.358  1.00 72.86  ? 212  VAL D C   1 
ATOM   9401  O O   . VAL D 1 137 ? -37.086 22.565  72.955  1.00 68.85  ? 212  VAL D O   1 
ATOM   9402  C CB  . VAL D 1 137 ? -34.369 21.914  74.210  1.00 58.80  ? 212  VAL D CB  1 
ATOM   9403  C CG1 . VAL D 1 137 ? -34.420 20.455  73.805  1.00 64.08  ? 212  VAL D CG1 1 
ATOM   9404  C CG2 . VAL D 1 137 ? -33.000 22.258  74.762  1.00 49.10  ? 212  VAL D CG2 1 
ATOM   9405  N N   . ARG D 1 138 ? -35.934 21.944  71.113  1.00 69.80  ? 213  ARG D N   1 
ATOM   9406  C CA  . ARG D 1 138 ? -37.154 21.614  70.383  1.00 68.98  ? 213  ARG D CA  1 
ATOM   9407  C C   . ARG D 1 138 ? -37.911 20.473  71.047  1.00 72.09  ? 213  ARG D C   1 
ATOM   9408  O O   . ARG D 1 138 ? -39.145 20.450  71.027  1.00 77.30  ? 213  ARG D O   1 
ATOM   9409  C CB  . ARG D 1 138 ? -36.850 21.251  68.931  1.00 58.89  ? 213  ARG D CB  1 
ATOM   9410  C CG  . ARG D 1 138 ? -38.119 21.181  68.088  1.00 66.12  ? 213  ARG D CG  1 
ATOM   9411  C CD  . ARG D 1 138 ? -37.847 20.995  66.608  1.00 61.03  ? 213  ARG D CD  1 
ATOM   9412  N NE  . ARG D 1 138 ? -37.057 22.080  66.042  1.00 54.29  ? 213  ARG D NE  1 
ATOM   9413  C CZ  . ARG D 1 138 ? -36.513 22.048  64.835  1.00 65.82  ? 213  ARG D CZ  1 
ATOM   9414  N NH1 . ARG D 1 138 ? -36.678 21.011  64.029  1.00 63.76  ? 213  ARG D NH1 1 
ATOM   9415  N NH2 . ARG D 1 138 ? -35.785 23.082  64.424  1.00 74.15  ? 213  ARG D NH2 1 
ATOM   9416  N N   . ALA D 1 139 ? -37.194 19.512  71.631  1.00 63.90  ? 214  ALA D N   1 
ATOM   9417  C CA  . ALA D 1 139 ? -37.869 18.402  72.296  1.00 63.34  ? 214  ALA D CA  1 
ATOM   9418  C C   . ALA D 1 139 ? -38.742 18.907  73.437  1.00 64.71  ? 214  ALA D C   1 
ATOM   9419  O O   . ALA D 1 139 ? -39.950 18.628  73.489  1.00 71.03  ? 214  ALA D O   1 
ATOM   9420  C CB  . ALA D 1 139 ? -36.842 17.390  72.804  1.00 62.27  ? 214  ALA D CB  1 
ATOM   9421  N N   . PHE D 1 140 ? -38.141 19.667  74.357  1.00 56.77  ? 215  PHE D N   1 
ATOM   9422  C CA  . PHE D 1 140 ? -38.889 20.225  75.478  1.00 61.12  ? 215  PHE D CA  1 
ATOM   9423  C C   . PHE D 1 140 ? -40.045 21.089  74.992  1.00 67.79  ? 215  PHE D C   1 
ATOM   9424  O O   . PHE D 1 140 ? -41.179 20.937  75.454  1.00 78.99  ? 215  PHE D O   1 
ATOM   9425  C CB  . PHE D 1 140 ? -37.960 21.038  76.382  1.00 58.45  ? 215  PHE D CB  1 
ATOM   9426  C CG  . PHE D 1 140 ? -37.009 20.201  77.192  1.00 66.11  ? 215  PHE D CG  1 
ATOM   9427  C CD1 . PHE D 1 140 ? -37.418 18.995  77.734  1.00 62.11  ? 215  PHE D CD1 1 
ATOM   9428  C CD2 . PHE D 1 140 ? -35.713 20.632  77.429  1.00 66.98  ? 215  PHE D CD2 1 
ATOM   9429  C CE1 . PHE D 1 140 ? -36.549 18.222  78.485  1.00 62.26  ? 215  PHE D CE1 1 
ATOM   9430  C CE2 . PHE D 1 140 ? -34.838 19.865  78.182  1.00 69.70  ? 215  PHE D CE2 1 
ATOM   9431  C CZ  . PHE D 1 140 ? -35.258 18.658  78.710  1.00 68.54  ? 215  PHE D CZ  1 
ATOM   9432  N N   . ARG D 1 141 ? -39.775 22.001  74.052  1.00 60.94  ? 216  ARG D N   1 
ATOM   9433  C CA  . ARG D 1 141 ? -40.806 22.933  73.601  1.00 59.23  ? 216  ARG D CA  1 
ATOM   9434  C C   . ARG D 1 141 ? -41.978 22.197  72.962  1.00 63.09  ? 216  ARG D C   1 
ATOM   9435  O O   . ARG D 1 141 ? -43.140 22.449  73.298  1.00 77.30  ? 216  ARG D O   1 
ATOM   9436  C CB  . ARG D 1 141 ? -40.212 23.943  72.619  1.00 55.49  ? 216  ARG D CB  1 
ATOM   9437  C CG  . ARG D 1 141 ? -41.082 25.171  72.411  1.00 61.47  ? 216  ARG D CG  1 
ATOM   9438  C CD  . ARG D 1 141 ? -40.275 26.360  71.913  1.00 63.52  ? 216  ARG D CD  1 
ATOM   9439  N NE  . ARG D 1 141 ? -39.975 26.257  70.489  1.00 71.44  ? 216  ARG D NE  1 
ATOM   9440  C CZ  . ARG D 1 141 ? -38.835 25.801  69.988  1.00 74.61  ? 216  ARG D CZ  1 
ATOM   9441  N NH1 . ARG D 1 141 ? -37.842 25.408  70.770  1.00 64.74  ? 216  ARG D NH1 1 
ATOM   9442  N NH2 . ARG D 1 141 ? -38.685 25.740  68.668  1.00 74.81  ? 216  ARG D NH2 1 
ATOM   9443  N N   . HIS D 1 142 ? -41.686 21.283  72.036  1.00 52.51  ? 217  HIS D N   1 
ATOM   9444  C CA  . HIS D 1 142 ? -42.723 20.519  71.350  1.00 57.38  ? 217  HIS D CA  1 
ATOM   9445  C C   . HIS D 1 142 ? -43.569 19.729  72.343  1.00 63.76  ? 217  HIS D C   1 
ATOM   9446  O O   . HIS D 1 142 ? -44.807 19.846  72.367  1.00 68.12  ? 217  HIS D O   1 
ATOM   9447  C CB  . HIS D 1 142 ? -42.060 19.588  70.329  1.00 64.07  ? 217  HIS D CB  1 
ATOM   9448  C CG  . HIS D 1 142 ? -43.002 19.002  69.323  1.00 63.39  ? 217  HIS D CG  1 
ATOM   9449  N ND1 . HIS D 1 142 ? -42.560 18.344  68.195  1.00 70.66  ? 217  HIS D ND1 1 
ATOM   9450  C CD2 . HIS D 1 142 ? -44.355 18.979  69.267  1.00 67.14  ? 217  HIS D CD2 1 
ATOM   9451  C CE1 . HIS D 1 142 ? -43.600 17.936  67.490  1.00 77.12  ? 217  HIS D CE1 1 
ATOM   9452  N NE2 . HIS D 1 142 ? -44.701 18.308  68.118  1.00 79.17  ? 217  HIS D NE2 1 
ATOM   9453  N N   . THR D 1 143 ? -42.912 18.914  73.178  1.00 63.76  ? 218  THR D N   1 
ATOM   9454  C CA  . THR D 1 143 ? -43.644 18.078  74.123  1.00 60.81  ? 218  THR D CA  1 
ATOM   9455  C C   . THR D 1 143 ? -44.479 18.924  75.077  1.00 59.24  ? 218  THR D C   1 
ATOM   9456  O O   . THR D 1 143 ? -45.658 18.630  75.318  1.00 60.52  ? 218  THR D O   1 
ATOM   9457  C CB  . THR D 1 143 ? -42.669 17.187  74.897  1.00 55.68  ? 218  THR D CB  1 
ATOM   9458  O OG1 . THR D 1 143 ? -41.746 16.577  73.984  1.00 66.78  ? 218  THR D OG1 1 
ATOM   9459  C CG2 . THR D 1 143 ? -43.418 16.103  75.653  1.00 50.64  ? 218  THR D CG2 1 
ATOM   9460  N N   . SER D 1 144 ? -43.890 19.997  75.615  1.00 54.21  ? 219  SER D N   1 
ATOM   9461  C CA  . SER D 1 144 ? -44.587 20.806  76.606  1.00 57.43  ? 219  SER D CA  1 
ATOM   9462  C C   . SER D 1 144 ? -45.756 21.554  75.990  1.00 56.17  ? 219  SER D C   1 
ATOM   9463  O O   . SER D 1 144 ? -46.800 21.707  76.629  1.00 58.64  ? 219  SER D O   1 
ATOM   9464  C CB  . SER D 1 144 ? -43.626 21.795  77.255  1.00 51.65  ? 219  SER D CB  1 
ATOM   9465  O OG  . SER D 1 144 ? -42.656 22.240  76.327  1.00 68.99  ? 219  SER D OG  1 
ATOM   9466  N N   . THR D 1 145 ? -45.604 22.037  74.755  1.00 46.35  ? 220  THR D N   1 
ATOM   9467  C CA  . THR D 1 145 ? -46.707 22.739  74.112  1.00 46.97  ? 220  THR D CA  1 
ATOM   9468  C C   . THR D 1 145 ? -47.870 21.795  73.847  1.00 55.31  ? 220  THR D C   1 
ATOM   9469  O O   . THR D 1 145 ? -49.033 22.149  74.088  1.00 67.57  ? 220  THR D O   1 
ATOM   9470  C CB  . THR D 1 145 ? -46.239 23.387  72.812  1.00 49.78  ? 220  THR D CB  1 
ATOM   9471  O OG1 . THR D 1 145 ? -45.183 24.315  73.091  1.00 51.37  ? 220  THR D OG1 1 
ATOM   9472  C CG2 . THR D 1 145 ? -47.392 24.125  72.158  1.00 47.69  ? 220  THR D CG2 1 
ATOM   9473  N N   . LEU D 1 146 ? -47.580 20.586  73.356  1.00 49.07  ? 221  LEU D N   1 
ATOM   9474  C CA  . LEU D 1 146 ? -48.653 19.613  73.161  1.00 56.03  ? 221  LEU D CA  1 
ATOM   9475  C C   . LEU D 1 146 ? -49.351 19.301  74.482  1.00 62.76  ? 221  LEU D C   1 
ATOM   9476  O O   . LEU D 1 146 ? -50.591 19.277  74.563  1.00 67.29  ? 221  LEU D O   1 
ATOM   9477  C CB  . LEU D 1 146 ? -48.101 18.337  72.528  1.00 54.60  ? 221  LEU D CB  1 
ATOM   9478  C CG  . LEU D 1 146 ? -49.097 17.180  72.438  1.00 49.10  ? 221  LEU D CG  1 
ATOM   9479  C CD1 . LEU D 1 146 ? -50.032 17.372  71.256  1.00 44.61  ? 221  LEU D CD1 1 
ATOM   9480  C CD2 . LEU D 1 146 ? -48.372 15.850  72.345  1.00 50.90  ? 221  LEU D CD2 1 
ATOM   9481  N N   . ALA D 1 147 ? -48.561 19.068  75.535  1.00 49.14  ? 222  ALA D N   1 
ATOM   9482  C CA  . ALA D 1 147 ? -49.132 18.764  76.842  1.00 47.57  ? 222  ALA D CA  1 
ATOM   9483  C C   . ALA D 1 147 ? -49.984 19.916  77.358  1.00 57.57  ? 222  ALA D C   1 
ATOM   9484  O O   . ALA D 1 147 ? -51.044 19.695  77.951  1.00 64.08  ? 222  ALA D O   1 
ATOM   9485  C CB  . ALA D 1 147 ? -48.016 18.437  77.833  1.00 58.35  ? 222  ALA D CB  1 
ATOM   9486  N N   . ALA D 1 148 ? -49.535 21.153  77.141  1.00 60.86  ? 223  ALA D N   1 
ATOM   9487  C CA  . ALA D 1 148 ? -50.268 22.312  77.636  1.00 47.70  ? 223  ALA D CA  1 
ATOM   9488  C C   . ALA D 1 148 ? -51.581 22.488  76.894  1.00 52.69  ? 223  ALA D C   1 
ATOM   9489  O O   . ALA D 1 148 ? -52.601 22.827  77.502  1.00 57.53  ? 223  ALA D O   1 
ATOM   9490  C CB  . ALA D 1 148 ? -49.410 23.569  77.509  1.00 45.63  ? 223  ALA D CB  1 
ATOM   9491  N N   . MET D 1 149 ? -51.580 22.255  75.579  1.00 48.32  ? 224  MET D N   1 
ATOM   9492  C CA  . MET D 1 149 ? -52.832 22.327  74.831  1.00 45.43  ? 224  MET D CA  1 
ATOM   9493  C C   . MET D 1 149 ? -53.820 21.260  75.295  1.00 55.52  ? 224  MET D C   1 
ATOM   9494  O O   . MET D 1 149 ? -55.014 21.546  75.473  1.00 58.79  ? 224  MET D O   1 
ATOM   9495  C CB  . MET D 1 149 ? -52.559 22.213  73.332  1.00 29.78  ? 224  MET D CB  1 
ATOM   9496  C CG  . MET D 1 149 ? -51.652 23.303  72.795  1.00 49.56  ? 224  MET D CG  1 
ATOM   9497  S SD  . MET D 1 149 ? -52.302 24.934  73.199  1.00 53.13  ? 224  MET D SD  1 
ATOM   9498  C CE  . MET D 1 149 ? -50.794 25.876  73.401  1.00 53.48  ? 224  MET D CE  1 
ATOM   9499  N N   . LYS D 1 150 ? -53.345 20.030  75.518  1.00 50.07  ? 225  LYS D N   1 
ATOM   9500  C CA  . LYS D 1 150 ? -54.248 18.987  76.003  1.00 51.24  ? 225  LYS D CA  1 
ATOM   9501  C C   . LYS D 1 150 ? -54.782 19.319  77.397  1.00 60.10  ? 225  LYS D C   1 
ATOM   9502  O O   . LYS D 1 150 ? -55.986 19.172  77.670  1.00 66.66  ? 225  LYS D O   1 
ATOM   9503  C CB  . LYS D 1 150 ? -53.531 17.637  76.004  1.00 46.68  ? 225  LYS D CB  1 
ATOM   9504  C CG  . LYS D 1 150 ? -53.161 17.131  74.614  1.00 47.91  ? 225  LYS D CG  1 
ATOM   9505  C CD  . LYS D 1 150 ? -54.251 17.418  73.596  1.00 53.09  ? 225  LYS D CD  1 
ATOM   9506  C CE  . LYS D 1 150 ? -53.822 17.007  72.197  1.00 58.28  ? 225  LYS D CE  1 
ATOM   9507  N NZ  . LYS D 1 150 ? -54.987 16.804  71.294  1.00 60.90  ? 225  LYS D NZ  1 
ATOM   9508  N N   . LEU D 1 151 ? -53.893 19.774  78.286  1.00 54.09  ? 226  LEU D N   1 
ATOM   9509  C CA  . LEU D 1 151 ? -54.287 20.194  79.626  1.00 50.46  ? 226  LEU D CA  1 
ATOM   9510  C C   . LEU D 1 151 ? -55.336 21.296  79.583  1.00 59.67  ? 226  LEU D C   1 
ATOM   9511  O O   . LEU D 1 151 ? -56.309 21.268  80.348  1.00 63.28  ? 226  LEU D O   1 
ATOM   9512  C CB  . LEU D 1 151 ? -53.053 20.662  80.397  1.00 45.22  ? 226  LEU D CB  1 
ATOM   9513  C CG  . LEU D 1 151 ? -53.217 21.283  81.784  1.00 52.04  ? 226  LEU D CG  1 
ATOM   9514  C CD1 . LEU D 1 151 ? -54.033 20.401  82.698  1.00 45.01  ? 226  LEU D CD1 1 
ATOM   9515  C CD2 . LEU D 1 151 ? -51.856 21.554  82.399  1.00 65.69  ? 226  LEU D CD2 1 
ATOM   9516  N N   . MET D 1 152 ? -55.163 22.274  78.692  1.00 51.61  ? 227  MET D N   1 
ATOM   9517  C CA  . MET D 1 152 ? -56.125 23.367  78.633  1.00 54.02  ? 227  MET D CA  1 
ATOM   9518  C C   . MET D 1 152 ? -57.458 22.901  78.068  1.00 54.35  ? 227  MET D C   1 
ATOM   9519  O O   . MET D 1 152 ? -58.510 23.384  78.489  1.00 68.32  ? 227  MET D O   1 
ATOM   9520  C CB  . MET D 1 152 ? -55.579 24.532  77.812  1.00 47.82  ? 227  MET D CB  1 
ATOM   9521  C CG  . MET D 1 152 ? -56.637 25.589  77.542  1.00 41.66  ? 227  MET D CG  1 
ATOM   9522  S SD  . MET D 1 152 ? -56.086 27.279  77.790  1.00 65.65  ? 227  MET D SD  1 
ATOM   9523  C CE  . MET D 1 152 ? -57.640 28.154  77.627  1.00 49.02  ? 227  MET D CE  1 
ATOM   9524  N N   . THR D 1 153 ? -57.443 21.974  77.109  1.00 51.19  ? 228  THR D N   1 
ATOM   9525  C CA  . THR D 1 153 ? -58.709 21.421  76.633  1.00 57.55  ? 228  THR D CA  1 
ATOM   9526  C C   . THR D 1 153 ? -59.464 20.736  77.769  1.00 54.76  ? 228  THR D C   1 
ATOM   9527  O O   . THR D 1 153 ? -60.682 20.922  77.930  1.00 52.22  ? 228  THR D O   1 
ATOM   9528  C CB  . THR D 1 153 ? -58.453 20.450  75.482  1.00 58.86  ? 228  THR D CB  1 
ATOM   9529  O OG1 . THR D 1 153 ? -58.113 21.191  74.303  1.00 59.42  ? 228  THR D OG1 1 
ATOM   9530  C CG2 . THR D 1 153 ? -59.694 19.614  75.205  1.00 47.02  ? 228  THR D CG2 1 
ATOM   9531  N N   . ALA D 1 154 ? -58.749 19.954  78.581  1.00 50.98  ? 229  ALA D N   1 
ATOM   9532  C CA  . ALA D 1 154 ? -59.387 19.321  79.733  1.00 67.04  ? 229  ALA D CA  1 
ATOM   9533  C C   . ALA D 1 154 ? -59.921 20.362  80.716  1.00 62.98  ? 229  ALA D C   1 
ATOM   9534  O O   . ALA D 1 154 ? -61.032 20.219  81.251  1.00 64.97  ? 229  ALA D O   1 
ATOM   9535  C CB  . ALA D 1 154 ? -58.401 18.379  80.416  1.00 49.69  ? 229  ALA D CB  1 
ATOM   9536  N N   . LEU D 1 155 ? -59.149 21.426  80.955  1.00 56.20  ? 230  LEU D N   1 
ATOM   9537  C CA  . LEU D 1 155 ? -59.608 22.496  81.838  1.00 50.70  ? 230  LEU D CA  1 
ATOM   9538  C C   . LEU D 1 155 ? -60.851 23.180  81.280  1.00 56.16  ? 230  LEU D C   1 
ATOM   9539  O O   . LEU D 1 155 ? -61.738 23.592  82.037  1.00 65.28  ? 230  LEU D O   1 
ATOM   9540  C CB  . LEU D 1 155 ? -58.493 23.520  82.050  1.00 50.95  ? 230  LEU D CB  1 
ATOM   9541  C CG  . LEU D 1 155 ? -57.283 23.120  82.893  1.00 54.58  ? 230  LEU D CG  1 
ATOM   9542  C CD1 . LEU D 1 155 ? -56.161 24.128  82.707  1.00 52.86  ? 230  LEU D CD1 1 
ATOM   9543  C CD2 . LEU D 1 155 ? -57.667 23.011  84.355  1.00 52.94  ? 230  LEU D CD2 1 
ATOM   9544  N N   . VAL D 1 156 ? -60.923 23.324  79.956  1.00 58.72  ? 231  VAL D N   1 
ATOM   9545  C CA  . VAL D 1 156 ? -62.096 23.918  79.321  1.00 54.92  ? 231  VAL D CA  1 
ATOM   9546  C C   . VAL D 1 156 ? -63.320 23.049  79.556  1.00 59.71  ? 231  VAL D C   1 
ATOM   9547  O O   . VAL D 1 156 ? -64.414 23.555  79.838  1.00 63.84  ? 231  VAL D O   1 
ATOM   9548  C CB  . VAL D 1 156 ? -61.840 24.140  77.818  1.00 40.25  ? 231  VAL D CB  1 
ATOM   9549  C CG1 . VAL D 1 156 ? -63.121 24.543  77.120  1.00 48.28  ? 231  VAL D CG1 1 
ATOM   9550  C CG2 . VAL D 1 156 ? -60.795 25.216  77.613  1.00 45.76  ? 231  VAL D CG2 1 
ATOM   9551  N N   . ASN D 1 157 ? -63.161 21.728  79.443  1.00 59.10  ? 232  ASN D N   1 
ATOM   9552  C CA  . ASN D 1 157 ? -64.289 20.847  79.740  1.00 54.86  ? 232  ASN D CA  1 
ATOM   9553  C C   . ASN D 1 157 ? -64.718 20.982  81.198  1.00 56.06  ? 232  ASN D C   1 
ATOM   9554  O O   . ASN D 1 157 ? -65.919 20.989  81.507  1.00 67.07  ? 232  ASN D O   1 
ATOM   9555  C CB  . ASN D 1 157 ? -63.942 19.396  79.417  1.00 55.49  ? 232  ASN D CB  1 
ATOM   9556  C CG  . ASN D 1 157 ? -65.111 18.460  79.655  1.00 76.32  ? 232  ASN D CG  1 
ATOM   9557  O OD1 . ASN D 1 157 ? -64.968 17.413  80.285  1.00 109.48 ? 232  ASN D OD1 1 
ATOM   9558  N ND2 . ASN D 1 157 ? -66.282 18.838  79.152  1.00 59.83  ? 232  ASN D ND2 1 
ATOM   9559  N N   . VAL D 1 158 ? -63.745 21.095  82.108  1.00 52.17  ? 233  VAL D N   1 
ATOM   9560  C CA  . VAL D 1 158 ? -64.064 21.309  83.522  1.00 55.40  ? 233  VAL D CA  1 
ATOM   9561  C C   . VAL D 1 158 ? -64.875 22.589  83.701  1.00 59.06  ? 233  VAL D C   1 
ATOM   9562  O O   . VAL D 1 158 ? -65.885 22.614  84.417  1.00 61.70  ? 233  VAL D O   1 
ATOM   9563  C CB  . VAL D 1 158 ? -62.780 21.339  84.369  1.00 40.23  ? 233  VAL D CB  1 
ATOM   9564  C CG1 . VAL D 1 158 ? -63.120 21.587  85.824  1.00 43.00  ? 233  VAL D CG1 1 
ATOM   9565  C CG2 . VAL D 1 158 ? -62.027 20.033  84.230  1.00 55.25  ? 233  VAL D CG2 1 
ATOM   9566  N N   . ALA D 1 159 ? -64.441 23.674  83.057  1.00 55.61  ? 234  ALA D N   1 
ATOM   9567  C CA  . ALA D 1 159 ? -65.129 24.955  83.202  1.00 57.33  ? 234  ALA D CA  1 
ATOM   9568  C C   . ALA D 1 159 ? -66.535 24.901  82.614  1.00 56.97  ? 234  ALA D C   1 
ATOM   9569  O O   . ALA D 1 159 ? -67.469 25.503  83.160  1.00 57.41  ? 234  ALA D O   1 
ATOM   9570  C CB  . ALA D 1 159 ? -64.310 26.064  82.543  1.00 55.45  ? 234  ALA D CB  1 
ATOM   9571  N N   . LEU D 1 160 ? -66.704 24.184  81.502  1.00 51.63  ? 235  LEU D N   1 
ATOM   9572  C CA  . LEU D 1 160 ? -68.029 24.025  80.913  1.00 55.01  ? 235  LEU D CA  1 
ATOM   9573  C C   . LEU D 1 160 ? -68.960 23.274  81.859  1.00 64.03  ? 235  LEU D C   1 
ATOM   9574  O O   . LEU D 1 160 ? -70.121 23.669  82.048  1.00 57.64  ? 235  LEU D O   1 
ATOM   9575  C CB  . LEU D 1 160 ? -67.915 23.299  79.573  1.00 43.56  ? 235  LEU D CB  1 
ATOM   9576  C CG  . LEU D 1 160 ? -69.205 22.778  78.941  1.00 47.76  ? 235  LEU D CG  1 
ATOM   9577  C CD1 . LEU D 1 160 ? -70.080 23.935  78.487  1.00 53.59  ? 235  LEU D CD1 1 
ATOM   9578  C CD2 . LEU D 1 160 ? -68.888 21.852  77.778  1.00 60.57  ? 235  LEU D CD2 1 
ATOM   9579  N N   . ASN D 1 161 ? -68.469 22.187  82.463  1.00 60.55  ? 236  ASN D N   1 
ATOM   9580  C CA  . ASN D 1 161 ? -69.279 21.464  83.441  1.00 51.13  ? 236  ASN D CA  1 
ATOM   9581  C C   . ASN D 1 161 ? -69.621 22.350  84.633  1.00 58.02  ? 236  ASN D C   1 
ATOM   9582  O O   . ASN D 1 161 ? -70.736 22.286  85.166  1.00 69.52  ? 236  ASN D O   1 
ATOM   9583  C CB  . ASN D 1 161 ? -68.554 20.203  83.908  1.00 51.61  ? 236  ASN D CB  1 
ATOM   9584  C CG  . ASN D 1 161 ? -68.203 19.275  82.765  1.00 62.08  ? 236  ASN D CG  1 
ATOM   9585  O OD1 . ASN D 1 161 ? -68.940 19.169  81.785  1.00 58.04  ? 236  ASN D OD1 1 
ATOM   9586  N ND2 . ASN D 1 161 ? -67.071 18.592  82.888  1.00 78.09  ? 236  ASN D ND2 1 
ATOM   9587  N N   . LEU D 1 162 ? -68.668 23.178  85.067  1.00 63.34  ? 237  LEU D N   1 
ATOM   9588  C CA  . LEU D 1 162 ? -68.935 24.106  86.162  1.00 62.20  ? 237  LEU D CA  1 
ATOM   9589  C C   . LEU D 1 162 ? -70.047 25.080  85.799  1.00 67.89  ? 237  LEU D C   1 
ATOM   9590  O O   . LEU D 1 162 ? -70.933 25.354  86.616  1.00 66.43  ? 237  LEU D O   1 
ATOM   9591  C CB  . LEU D 1 162 ? -67.663 24.865  86.534  1.00 49.12  ? 237  LEU D CB  1 
ATOM   9592  C CG  . LEU D 1 162 ? -66.619 24.100  87.342  1.00 48.84  ? 237  LEU D CG  1 
ATOM   9593  C CD1 . LEU D 1 162 ? -65.323 24.889  87.421  1.00 59.41  ? 237  LEU D CD1 1 
ATOM   9594  C CD2 . LEU D 1 162 ? -67.155 23.806  88.729  1.00 58.62  ? 237  LEU D CD2 1 
ATOM   9595  N N   . SER D 1 163 ? -70.015 25.614  84.576  1.00 68.45  ? 238  SER D N   1 
ATOM   9596  C CA  . SER D 1 163 ? -71.056 26.548  84.155  1.00 62.06  ? 238  SER D CA  1 
ATOM   9597  C C   . SER D 1 163 ? -72.415 25.865  84.091  1.00 66.28  ? 238  SER D C   1 
ATOM   9598  O O   . SER D 1 163 ? -73.427 26.447  84.498  1.00 80.22  ? 238  SER D O   1 
ATOM   9599  C CB  . SER D 1 163 ? -70.704 27.162  82.801  1.00 64.65  ? 238  SER D CB  1 
ATOM   9600  O OG  . SER D 1 163 ? -70.986 26.261  81.746  1.00 75.18  ? 238  SER D OG  1 
ATOM   9601  N N   . ILE D 1 164 ? -72.459 24.628  83.589  1.00 66.49  ? 239  ILE D N   1 
ATOM   9602  C CA  . ILE D 1 164 ? -73.726 23.898  83.531  1.00 62.90  ? 239  ILE D CA  1 
ATOM   9603  C C   . ILE D 1 164 ? -74.280 23.680  84.935  1.00 73.65  ? 239  ILE D C   1 
ATOM   9604  O O   . ILE D 1 164 ? -75.470 23.902  85.199  1.00 84.73  ? 239  ILE D O   1 
ATOM   9605  C CB  . ILE D 1 164 ? -73.551 22.566  82.779  1.00 48.30  ? 239  ILE D CB  1 
ATOM   9606  C CG1 . ILE D 1 164 ? -73.120 22.817  81.332  1.00 54.47  ? 239  ILE D CG1 1 
ATOM   9607  C CG2 . ILE D 1 164 ? -74.834 21.753  82.825  1.00 62.65  ? 239  ILE D CG2 1 
ATOM   9608  C CD1 . ILE D 1 164 ? -72.478 21.620  80.663  1.00 56.04  ? 239  ILE D CD1 1 
ATOM   9609  N N   . ASN D 1 165 ? -73.418 23.250  85.862  1.00 76.99  ? 240  ASN D N   1 
ATOM   9610  C CA  . ASN D 1 165 ? -73.868 22.987  87.225  1.00 77.19  ? 240  ASN D CA  1 
ATOM   9611  C C   . ASN D 1 165 ? -74.312 24.271  87.916  1.00 86.86  ? 240  ASN D C   1 
ATOM   9612  O O   . ASN D 1 165 ? -75.257 24.266  88.715  1.00 97.30  ? 240  ASN D O   1 
ATOM   9613  C CB  . ASN D 1 165 ? -72.753 22.302  88.016  1.00 69.58  ? 240  ASN D CB  1 
ATOM   9614  C CG  . ASN D 1 165 ? -73.262 21.614  89.266  1.00 95.24  ? 240  ASN D CG  1 
ATOM   9615  O OD1 . ASN D 1 165 ? -74.414 21.182  89.326  1.00 105.74 ? 240  ASN D OD1 1 
ATOM   9616  N ND2 . ASN D 1 165 ? -72.404 21.510  90.275  1.00 101.97 ? 240  ASN D ND2 1 
ATOM   9617  N N   . MET D 1 166 ? -73.646 25.386  87.615  1.00 75.98  ? 241  MET D N   1 
ATOM   9618  C CA  . MET D 1 166 ? -74.057 26.667  88.175  1.00 77.98  ? 241  MET D CA  1 
ATOM   9619  C C   . MET D 1 166 ? -75.406 27.107  87.624  1.00 83.58  ? 241  MET D C   1 
ATOM   9620  O O   . MET D 1 166 ? -76.239 27.635  88.369  1.00 95.02  ? 241  MET D O   1 
ATOM   9621  C CB  . MET D 1 166 ? -72.986 27.716  87.900  1.00 71.81  ? 241  MET D CB  1 
ATOM   9622  C CG  . MET D 1 166 ? -72.380 28.293  89.155  1.00 70.61  ? 241  MET D CG  1 
ATOM   9623  S SD  . MET D 1 166 ? -70.934 29.286  88.786  1.00 111.11 ? 241  MET D SD  1 
ATOM   9624  C CE  . MET D 1 166 ? -69.819 27.980  88.273  1.00 90.74  ? 241  MET D CE  1 
ATOM   9625  N N   . ASP D 1 167 ? -75.641 26.907  86.325  1.00 79.92  ? 242  ASP D N   1 
ATOM   9626  C CA  . ASP D 1 167 ? -76.969 27.168  85.777  1.00 82.05  ? 242  ASP D CA  1 
ATOM   9627  C C   . ASP D 1 167 ? -78.022 26.323  86.480  1.00 89.47  ? 242  ASP D C   1 
ATOM   9628  O O   . ASP D 1 167 ? -79.115 26.811  86.795  1.00 89.73  ? 242  ASP D O   1 
ATOM   9629  C CB  . ASP D 1 167 ? -76.988 26.896  84.273  1.00 73.96  ? 242  ASP D CB  1 
ATOM   9630  C CG  . ASP D 1 167 ? -76.019 27.773  83.510  1.00 89.00  ? 242  ASP D CG  1 
ATOM   9631  O OD1 . ASP D 1 167 ? -75.621 28.829  84.044  1.00 90.95  ? 242  ASP D OD1 1 
ATOM   9632  O OD2 . ASP D 1 167 ? -75.658 27.403  82.372  1.00 102.23 ? 242  ASP D OD2 1 
ATOM   9633  N N   . ASN D 1 168 ? -77.708 25.050  86.738  1.00 93.46  ? 243  ASN D N   1 
ATOM   9634  C CA  . ASN D 1 168 ? -78.662 24.181  87.423  1.00 87.11  ? 243  ASN D CA  1 
ATOM   9635  C C   . ASN D 1 168 ? -78.946 24.669  88.839  1.00 98.47  ? 243  ASN D C   1 
ATOM   9636  O O   . ASN D 1 168 ? -80.104 24.699  89.267  1.00 109.54 ? 243  ASN D O   1 
ATOM   9637  C CB  . ASN D 1 168 ? -78.155 22.740  87.440  1.00 94.88  ? 243  ASN D CB  1 
ATOM   9638  C CG  . ASN D 1 168 ? -77.910 22.195  86.048  1.00 137.04 ? 243  ASN D CG  1 
ATOM   9639  O OD1 . ASN D 1 168 ? -78.547 22.622  85.084  1.00 180.44 ? 243  ASN D OD1 1 
ATOM   9640  N ND2 . ASN D 1 168 ? -76.992 21.241  85.935  1.00 174.60 ? 243  ASN D ND2 1 
ATOM   9641  N N   . THR D 1 169 ? -77.906 25.055  89.583  1.00 87.03  ? 244  THR D N   1 
ATOM   9642  C CA  . THR D 1 169 ? -78.127 25.556  90.938  1.00 91.40  ? 244  THR D CA  1 
ATOM   9643  C C   . THR D 1 169 ? -78.911 26.863  90.924  1.00 89.63  ? 244  THR D C   1 
ATOM   9644  O O   . THR D 1 169 ? -79.778 27.081  91.776  1.00 93.12  ? 244  THR D O   1 
ATOM   9645  C CB  . THR D 1 169 ? -76.799 25.739  91.675  1.00 79.02  ? 244  THR D CB  1 
ATOM   9646  O OG1 . THR D 1 169 ? -76.003 26.721  91.002  1.00 104.64 ? 244  THR D OG1 1 
ATOM   9647  C CG2 . THR D 1 169 ? -76.038 24.423  91.758  1.00 67.03  ? 244  THR D CG2 1 
ATOM   9648  N N   . GLN D 1 170 ? -78.636 27.739  89.954  1.00 88.41  ? 245  GLN D N   1 
ATOM   9649  C CA  . GLN D 1 170 ? -79.360 29.003  89.874  1.00 90.75  ? 245  GLN D CA  1 
ATOM   9650  C C   . GLN D 1 170 ? -80.833 28.772  89.559  1.00 91.89  ? 245  GLN D C   1 
ATOM   9651  O O   . GLN D 1 170 ? -81.713 29.373  90.185  1.00 101.36 ? 245  GLN D O   1 
ATOM   9652  C CB  . GLN D 1 170 ? -78.710 29.910  88.826  1.00 93.86  ? 245  GLN D CB  1 
ATOM   9653  C CG  . GLN D 1 170 ? -79.418 31.242  88.620  1.00 102.63 ? 245  GLN D CG  1 
ATOM   9654  C CD  . GLN D 1 170 ? -79.498 32.071  89.889  1.00 123.94 ? 245  GLN D CD  1 
ATOM   9655  O OE1 . GLN D 1 170 ? -80.587 32.405  90.355  1.00 131.89 ? 245  GLN D OE1 1 
ATOM   9656  N NE2 . GLN D 1 170 ? -78.342 32.419  90.445  1.00 109.53 ? 245  GLN D NE2 1 
ATOM   9657  N N   . ARG D 1 171 ? -81.124 27.882  88.606  1.00 93.10  ? 246  ARG D N   1 
ATOM   9658  C CA  . ARG D 1 171 ? -82.512 27.614  88.243  1.00 93.66  ? 246  ARG D CA  1 
ATOM   9659  C C   . ARG D 1 171 ? -83.242 26.861  89.351  1.00 94.43  ? 246  ARG D C   1 
ATOM   9660  O O   . ARG D 1 171 ? -84.441 27.076  89.566  1.00 107.34 ? 246  ARG D O   1 
ATOM   9661  C CB  . ARG D 1 171 ? -82.556 26.843  86.919  1.00 104.05 ? 246  ARG D CB  1 
ATOM   9662  C CG  . ARG D 1 171 ? -82.653 25.327  87.060  1.00 114.54 ? 246  ARG D CG  1 
ATOM   9663  C CD  . ARG D 1 171 ? -82.640 24.639  85.707  1.00 123.81 ? 246  ARG D CD  1 
ATOM   9664  N NE  . ARG D 1 171 ? -81.390 24.888  84.999  1.00 122.72 ? 246  ARG D NE  1 
ATOM   9665  C CZ  . ARG D 1 171 ? -81.289 25.150  83.703  1.00 118.99 ? 246  ARG D CZ  1 
ATOM   9666  N NH1 . ARG D 1 171 ? -82.358 25.275  82.934  1.00 120.85 ? 246  ARG D NH1 1 
ATOM   9667  N NH2 . ARG D 1 171 ? -80.081 25.287  83.163  1.00 115.41 ? 246  ARG D NH2 1 
ATOM   9668  N N   . GLN D 1 172 ? -82.526 26.010  90.087  1.00 90.12  ? 247  GLN D N   1 
ATOM   9669  C CA  . GLN D 1 172 ? -83.104 25.306  91.223  1.00 98.24  ? 247  GLN D CA  1 
ATOM   9670  C C   . GLN D 1 172 ? -83.429 26.274  92.352  1.00 97.29  ? 247  GLN D C   1 
ATOM   9671  O O   . GLN D 1 172 ? -84.488 26.172  92.987  1.00 105.04 ? 247  GLN D O   1 
ATOM   9672  C CB  . GLN D 1 172 ? -82.120 24.231  91.683  1.00 88.66  ? 247  GLN D CB  1 
ATOM   9673  C CG  . GLN D 1 172 ? -82.643 23.206  92.665  1.00 100.39 ? 247  GLN D CG  1 
ATOM   9674  C CD  . GLN D 1 172 ? -81.550 22.240  93.092  1.00 107.61 ? 247  GLN D CD  1 
ATOM   9675  O OE1 . GLN D 1 172 ? -80.533 22.098  92.409  1.00 72.12  ? 247  GLN D OE1 1 
ATOM   9676  N NE2 . GLN D 1 172 ? -81.750 21.573  94.224  1.00 128.69 ? 247  GLN D NE2 1 
ATOM   9677  N N   . TYR D 1 173 ? -82.528 27.223  92.612  1.00 94.79  ? 248  TYR D N   1 
ATOM   9678  C CA  . TYR D 1 173 ? -82.808 28.278  93.577  1.00 92.17  ? 248  TYR D CA  1 
ATOM   9679  C C   . TYR D 1 173 ? -83.986 29.130  93.129  1.00 99.50  ? 248  TYR D C   1 
ATOM   9680  O O   . TYR D 1 173 ? -84.797 29.557  93.953  1.00 125.24 ? 248  TYR D O   1 
ATOM   9681  C CB  . TYR D 1 173 ? -81.568 29.145  93.778  1.00 88.37  ? 248  TYR D CB  1 
ATOM   9682  C CG  . TYR D 1 173 ? -81.883 30.538  94.260  1.00 79.06  ? 248  TYR D CG  1 
ATOM   9683  C CD1 . TYR D 1 173 ? -82.272 30.765  95.572  1.00 83.75  ? 248  TYR D CD1 1 
ATOM   9684  C CD2 . TYR D 1 173 ? -81.807 31.626  93.400  1.00 87.43  ? 248  TYR D CD2 1 
ATOM   9685  C CE1 . TYR D 1 173 ? -82.566 32.036  96.020  1.00 93.79  ? 248  TYR D CE1 1 
ATOM   9686  C CE2 . TYR D 1 173 ? -82.100 32.902  93.839  1.00 89.41  ? 248  TYR D CE2 1 
ATOM   9687  C CZ  . TYR D 1 173 ? -82.479 33.101  95.151  1.00 95.18  ? 248  TYR D CZ  1 
ATOM   9688  O OH  . TYR D 1 173 ? -82.773 34.369  95.595  1.00 103.50 ? 248  TYR D OH  1 
ATOM   9689  N N   . GLU D 1 174 ? -84.096 29.391  91.824  1.00 81.30  ? 249  GLU D N   1 
ATOM   9690  C CA  . GLU D 1 174 ? -85.230 30.162  91.322  1.00 98.92  ? 249  GLU D CA  1 
ATOM   9691  C C   . GLU D 1 174 ? -86.538 29.405  91.507  1.00 103.18 ? 249  GLU D C   1 
ATOM   9692  O O   . GLU D 1 174 ? -87.576 30.006  91.810  1.00 109.08 ? 249  GLU D O   1 
ATOM   9693  C CB  . GLU D 1 174 ? -85.020 30.514  89.850  1.00 101.85 ? 249  GLU D CB  1 
ATOM   9694  C CG  . GLU D 1 174 ? -84.075 31.678  89.619  1.00 111.32 ? 249  GLU D CG  1 
ATOM   9695  C CD  . GLU D 1 174 ? -83.730 31.871  88.155  1.00 117.92 ? 249  GLU D CD  1 
ATOM   9696  O OE1 . GLU D 1 174 ? -84.199 31.071  87.317  1.00 113.10 ? 249  GLU D OE1 1 
ATOM   9697  O OE2 . GLU D 1 174 ? -82.988 32.827  87.844  1.00 114.79 ? 249  GLU D OE2 1 
ATOM   9698  N N   . ALA D 1 175 ? -86.509 28.084  91.321  1.00 101.61 ? 250  ALA D N   1 
ATOM   9699  C CA  . ALA D 1 175 ? -87.707 27.279  91.538  1.00 105.15 ? 250  ALA D CA  1 
ATOM   9700  C C   . ALA D 1 175 ? -88.098 27.268  93.010  1.00 115.08 ? 250  ALA D C   1 
ATOM   9701  O O   . ALA D 1 175 ? -89.271 27.456  93.352  1.00 132.27 ? 250  ALA D O   1 
ATOM   9702  C CB  . ALA D 1 175 ? -87.488 25.857  91.019  1.00 98.21  ? 250  ALA D CB  1 
ATOM   9703  N N   . GLU D 1 176 ? -87.125 27.052  93.900  1.00 105.92 ? 251  GLU D N   1 
ATOM   9704  C CA  . GLU D 1 176 ? -87.417 27.111  95.332  1.00 95.04  ? 251  GLU D CA  1 
ATOM   9705  C C   . GLU D 1 176 ? -87.905 28.495  95.743  1.00 106.15 ? 251  GLU D C   1 
ATOM   9706  O O   . GLU D 1 176 ? -88.764 28.620  96.623  1.00 120.02 ? 251  GLU D O   1 
ATOM   9707  C CB  . GLU D 1 176 ? -86.190 26.709  96.148  1.00 96.27  ? 251  GLU D CB  1 
ATOM   9708  C CG  . GLU D 1 176 ? -86.118 25.222  96.457  1.00 99.06  ? 251  GLU D CG  1 
ATOM   9709  C CD  . GLU D 1 176 ? -86.582 24.917  97.871  1.00 100.71 ? 251  GLU D CD  1 
ATOM   9710  O OE1 . GLU D 1 176 ? -86.859 25.876  98.622  1.00 98.44  ? 251  GLU D OE1 1 
ATOM   9711  O OE2 . GLU D 1 176 ? -86.667 23.726  98.237  1.00 106.19 ? 251  GLU D OE2 1 
ATOM   9712  N N   . ARG D 1 177 ? -87.369 29.546  95.121  1.00 101.31 ? 252  ARG D N   1 
ATOM   9713  C CA  . ARG D 1 177 ? -87.866 30.894  95.360  1.00 114.72 ? 252  ARG D CA  1 
ATOM   9714  C C   . ARG D 1 177 ? -89.346 30.960  95.004  1.00 138.79 ? 252  ARG D C   1 
ATOM   9715  O O   . ARG D 1 177 ? -90.189 31.322  95.835  1.00 160.11 ? 252  ARG D O   1 
ATOM   9716  C CB  . ARG D 1 177 ? -87.061 31.897  94.520  1.00 100.18 ? 252  ARG D CB  1 
ATOM   9717  C CG  . ARG D 1 177 ? -87.606 33.344  94.358  1.00 116.80 ? 252  ARG D CG  1 
ATOM   9718  C CD  . ARG D 1 177 ? -88.165 34.033  95.631  1.00 142.76 ? 252  ARG D CD  1 
ATOM   9719  N NE  . ARG D 1 177 ? -89.381 33.456  96.190  1.00 155.87 ? 252  ARG D NE  1 
ATOM   9720  C CZ  . ARG D 1 177 ? -90.023 33.910  97.259  1.00 156.07 ? 252  ARG D CZ  1 
ATOM   9721  N NH1 . ARG D 1 177 ? -89.769 35.105  97.766  1.00 150.98 ? 252  ARG D NH1 1 
ATOM   9722  N NH2 . ARG D 1 177 ? -90.929 33.134  97.847  1.00 157.99 ? 252  ARG D NH2 1 
ATOM   9723  N N   . ASN D 1 178 ? -89.673 30.596  93.760  1.00 135.27 ? 253  ASN D N   1 
ATOM   9724  C CA  . ASN D 1 178 ? -91.030 30.722  93.253  1.00 124.31 ? 253  ASN D CA  1 
ATOM   9725  C C   . ASN D 1 178 ? -92.035 29.990  94.129  1.00 147.06 ? 253  ASN D C   1 
ATOM   9726  O O   . ASN D 1 178 ? -93.200 30.397  94.201  1.00 170.73 ? 253  ASN D O   1 
ATOM   9727  C CB  . ASN D 1 178 ? -91.093 30.206  91.814  1.00 113.15 ? 253  ASN D CB  1 
ATOM   9728  C CG  . ASN D 1 178 ? -90.245 31.036  90.848  1.00 140.14 ? 253  ASN D CG  1 
ATOM   9729  O OD1 . ASN D 1 178 ? -90.240 32.265  90.912  1.00 135.77 ? 253  ASN D OD1 1 
ATOM   9730  N ND2 . ASN D 1 178 ? -89.539 30.364  89.937  1.00 152.88 ? 253  ASN D ND2 1 
ATOM   9731  N N   . LYS D 1 179 ? -91.615 28.917  94.795  1.00 143.89 ? 254  LYS D N   1 
ATOM   9732  C CA  . LYS D 1 179 ? -92.473 28.253  95.770  1.00 156.83 ? 254  LYS D CA  1 
ATOM   9733  C C   . LYS D 1 179 ? -92.747 29.196  96.938  1.00 161.30 ? 254  LYS D C   1 
ATOM   9734  O O   . LYS D 1 179 ? -91.815 29.730  97.547  1.00 161.60 ? 254  LYS D O   1 
ATOM   9735  C CB  . LYS D 1 179 ? -91.815 26.970  96.274  1.00 151.44 ? 254  LYS D CB  1 
ATOM   9736  C CG  . LYS D 1 179 ? -91.502 25.947  95.191  1.00 160.55 ? 254  LYS D CG  1 
ATOM   9737  C CD  . LYS D 1 179 ? -92.679 25.746  94.257  1.00 158.36 ? 254  LYS D CD  1 
ATOM   9738  C CE  . LYS D 1 179 ? -92.209 25.563  92.818  1.00 155.16 ? 254  LYS D CE  1 
ATOM   9739  N NZ  . LYS D 1 179 ? -91.721 26.835  92.201  1.00 161.67 ? 254  LYS D NZ  1 
ATOM   9740  N N   . MET D 1 180 ? -94.031 29.391  97.254  1.00 159.93 ? 255  MET D N   1 
ATOM   9741  C CA  . MET D 1 180 ? -94.459 30.269  98.346  1.00 162.70 ? 255  MET D CA  1 
ATOM   9742  C C   . MET D 1 180 ? -93.950 31.697  98.130  1.00 166.78 ? 255  MET D C   1 
ATOM   9743  O O   . MET D 1 180 ? -93.335 32.302  99.010  1.00 167.40 ? 255  MET D O   1 
ATOM   9744  C CB  . MET D 1 180 ? -94.008 29.720  99.706  1.00 167.58 ? 255  MET D CB  1 
ATOM   9745  C CG  . MET D 1 180 ? -95.000 28.760  100.344 1.00 160.79 ? 255  MET D CG  1 
ATOM   9746  S SD  . MET D 1 180 ? -96.447 29.589  101.028 1.00 148.80 ? 255  MET D SD  1 
ATOM   9747  C CE  . MET D 1 180 ? -97.703 29.108  99.843  1.00 128.61 ? 255  MET D CE  1 
ATOM   9748  N N   . ILE D 1 181 ? -94.225 32.242  96.944  1.00 173.46 ? 256  ILE D N   1 
ATOM   9749  C CA  . ILE D 1 181 ? -93.684 33.544  96.555  1.00 170.64 ? 256  ILE D CA  1 
ATOM   9750  C C   . ILE D 1 181 ? -94.460 34.681  97.206  1.00 171.91 ? 256  ILE D C   1 
ATOM   9751  O O   . ILE D 1 181 ? -93.965 35.311  98.142  1.00 181.11 ? 256  ILE D O   1 
ATOM   9752  C CB  . ILE D 1 181 ? -93.649 33.705  95.025  1.00 167.46 ? 256  ILE D CB  1 
ATOM   9753  C CG1 . ILE D 1 181 ? -92.643 34.789  94.643  1.00 159.73 ? 256  ILE D CG1 1 
ATOM   9754  C CG2 . ILE D 1 181 ? -95.030 34.063  94.500  1.00 155.16 ? 256  ILE D CG2 1 
ATOM   9755  C CD1 . ILE D 1 181 ? -91.875 34.493  93.379  1.00 141.73 ? 256  ILE D CD1 1 
ATOM   9756  N N   . ALA D 1 185 ? -87.936 26.416  103.450 1.00 128.41 ? 260  ALA D N   1 
ATOM   9757  C CA  . ALA D 1 185 ? -87.761 26.995  102.123 1.00 124.51 ? 260  ALA D CA  1 
ATOM   9758  C C   . ALA D 1 185 ? -86.576 27.956  102.095 1.00 115.29 ? 260  ALA D C   1 
ATOM   9759  O O   . ALA D 1 185 ? -85.691 27.834  101.249 1.00 128.46 ? 260  ALA D O   1 
ATOM   9760  C CB  . ALA D 1 185 ? -89.031 27.705  101.683 1.00 119.53 ? 260  ALA D CB  1 
ATOM   9761  N N   . ASN D 1 186 ? -86.575 28.920  103.021 1.00 110.60 ? 261  ASN D N   1 
ATOM   9762  C CA  . ASN D 1 186 ? -85.454 29.850  103.131 1.00 110.63 ? 261  ASN D CA  1 
ATOM   9763  C C   . ASN D 1 186 ? -84.147 29.097  103.346 1.00 118.33 ? 261  ASN D C   1 
ATOM   9764  O O   . ASN D 1 186 ? -83.115 29.426  102.741 1.00 133.65 ? 261  ASN D O   1 
ATOM   9765  C CB  . ASN D 1 186 ? -85.706 30.829  104.278 1.00 112.53 ? 261  ASN D CB  1 
ATOM   9766  C CG  . ASN D 1 186 ? -86.728 31.894  103.923 1.00 123.70 ? 261  ASN D CG  1 
ATOM   9767  O OD1 . ASN D 1 186 ? -87.663 32.153  104.684 1.00 125.52 ? 261  ASN D OD1 1 
ATOM   9768  N ND2 . ASN D 1 186 ? -86.555 32.518  102.766 1.00 123.35 ? 261  ASN D ND2 1 
ATOM   9769  N N   . GLU D 1 187 ? -84.186 28.080  104.209 1.00 112.84 ? 262  GLU D N   1 
ATOM   9770  C CA  . GLU D 1 187 ? -83.057 27.179  104.407 1.00 122.06 ? 262  GLU D CA  1 
ATOM   9771  C C   . GLU D 1 187 ? -82.499 26.675  103.079 1.00 116.03 ? 262  GLU D C   1 
ATOM   9772  O O   . GLU D 1 187 ? -81.294 26.778  102.814 1.00 112.09 ? 262  GLU D O   1 
ATOM   9773  C CB  . GLU D 1 187 ? -83.508 26.008  105.284 1.00 125.25 ? 262  GLU D CB  1 
ATOM   9774  C CG  . GLU D 1 187 ? -82.637 24.778  105.203 1.00 142.25 ? 262  GLU D CG  1 
ATOM   9775  C CD  . GLU D 1 187 ? -81.226 25.059  105.637 1.00 156.18 ? 262  GLU D CD  1 
ATOM   9776  O OE1 . GLU D 1 187 ? -81.054 25.565  106.763 1.00 154.16 ? 262  GLU D OE1 1 
ATOM   9777  O OE2 . GLU D 1 187 ? -80.296 24.771  104.855 1.00 197.53 ? 262  GLU D OE2 1 
ATOM   9778  N N   . ARG D 1 188 ? -83.371 26.135  102.226 1.00 119.84 ? 263  ARG D N   1 
ATOM   9779  C CA  . ARG D 1 188 ? -82.903 25.448  101.028 1.00 114.64 ? 263  ARG D CA  1 
ATOM   9780  C C   . ARG D 1 188 ? -82.373 26.432  99.995  1.00 101.35 ? 263  ARG D C   1 
ATOM   9781  O O   . ARG D 1 188 ? -81.322 26.196  99.389  1.00 110.84 ? 263  ARG D O   1 
ATOM   9782  C CB  . ARG D 1 188 ? -84.029 24.608  100.426 1.00 127.30 ? 263  ARG D CB  1 
ATOM   9783  C CG  . ARG D 1 188 ? -84.149 23.207  101.001 1.00 138.40 ? 263  ARG D CG  1 
ATOM   9784  C CD  . ARG D 1 188 ? -84.892 23.258  102.327 1.00 140.21 ? 263  ARG D CD  1 
ATOM   9785  N NE  . ARG D 1 188 ? -86.251 23.752  102.143 1.00 151.38 ? 263  ARG D NE  1 
ATOM   9786  C CZ  . ARG D 1 188 ? -87.216 23.087  101.520 1.00 152.81 ? 263  ARG D CZ  1 
ATOM   9787  N NH1 . ARG D 1 188 ? -87.027 21.858  101.064 1.00 163.30 ? 263  ARG D NH1 1 
ATOM   9788  N NH2 . ARG D 1 188 ? -88.403 23.664  101.360 1.00 151.62 ? 263  ARG D NH2 1 
ATOM   9789  N N   . LEU D 1 189 ? -83.090 27.537  99.770  1.00 95.62  ? 264  LEU D N   1 
ATOM   9790  C CA  . LEU D 1 189 ? -82.607 28.527  98.814  1.00 94.95  ? 264  LEU D CA  1 
ATOM   9791  C C   . LEU D 1 189 ? -81.303 29.157  99.282  1.00 94.31  ? 264  LEU D C   1 
ATOM   9792  O O   . LEU D 1 189 ? -80.477 29.562  98.456  1.00 107.89 ? 264  LEU D O   1 
ATOM   9793  C CB  . LEU D 1 189 ? -83.668 29.604  98.568  1.00 85.91  ? 264  LEU D CB  1 
ATOM   9794  C CG  . LEU D 1 189 ? -84.238 30.393  99.749  1.00 102.95 ? 264  LEU D CG  1 
ATOM   9795  C CD1 . LEU D 1 189 ? -83.490 31.708  99.956  1.00 112.77 ? 264  LEU D CD1 1 
ATOM   9796  C CD2 . LEU D 1 189 ? -85.724 30.647  99.541  1.00 113.29 ? 264  LEU D CD2 1 
ATOM   9797  N N   . GLU D 1 190 ? -81.075 29.214  100.597 1.00 90.76  ? 265  GLU D N   1 
ATOM   9798  C CA  . GLU D 1 190 ? -79.850 29.838  101.084 1.00 98.55  ? 265  GLU D CA  1 
ATOM   9799  C C   . GLU D 1 190 ? -78.671 28.866  100.974 1.00 97.62  ? 265  GLU D C   1 
ATOM   9800  O O   . GLU D 1 190 ? -77.554 29.274  100.612 1.00 104.48 ? 265  GLU D O   1 
ATOM   9801  C CB  . GLU D 1 190 ? -80.086 30.353  102.508 1.00 114.51 ? 265  GLU D CB  1 
ATOM   9802  C CG  . GLU D 1 190 ? -78.893 30.721  103.359 1.00 144.32 ? 265  GLU D CG  1 
ATOM   9803  C CD  . GLU D 1 190 ? -78.407 29.609  104.246 1.00 144.70 ? 265  GLU D CD  1 
ATOM   9804  O OE1 . GLU D 1 190 ? -79.244 28.902  104.852 1.00 170.93 ? 265  GLU D OE1 1 
ATOM   9805  O OE2 . GLU D 1 190 ? -77.176 29.535  104.423 1.00 128.20 ? 265  GLU D OE2 1 
ATOM   9806  N N   . LEU D 1 191 ? -78.915 27.574  101.243 1.00 100.07 ? 266  LEU D N   1 
ATOM   9807  C CA  . LEU D 1 191 ? -78.018 26.514  100.773 1.00 78.00  ? 266  LEU D CA  1 
ATOM   9808  C C   . LEU D 1 191 ? -77.664 26.679  99.300  1.00 74.57  ? 266  LEU D C   1 
ATOM   9809  O O   . LEU D 1 191 ? -76.494 26.572  98.918  1.00 77.32  ? 266  LEU D O   1 
ATOM   9810  C CB  . LEU D 1 191 ? -78.651 25.131  100.993 1.00 82.87  ? 266  LEU D CB  1 
ATOM   9811  C CG  . LEU D 1 191 ? -77.749 23.891  101.177 1.00 68.53  ? 266  LEU D CG  1 
ATOM   9812  C CD1 . LEU D 1 191 ? -76.848 23.930  102.392 1.00 66.35  ? 266  LEU D CD1 1 
ATOM   9813  C CD2 . LEU D 1 191 ? -78.587 22.613  101.196 1.00 95.58  ? 266  LEU D CD2 1 
ATOM   9814  N N   . LEU D 1 192 ? -78.677 26.869  98.450  1.00 70.84  ? 267  LEU D N   1 
ATOM   9815  C CA  . LEU D 1 192 ? -78.442 26.937  97.010  1.00 67.99  ? 267  LEU D CA  1 
ATOM   9816  C C   . LEU D 1 192 ? -77.560 28.130  96.655  1.00 80.95  ? 267  LEU D C   1 
ATOM   9817  O O   . LEU D 1 192 ? -76.660 28.023  95.811  1.00 91.01  ? 267  LEU D O   1 
ATOM   9818  C CB  . LEU D 1 192 ? -79.782 26.999  96.283  1.00 63.91  ? 267  LEU D CB  1 
ATOM   9819  C CG  . LEU D 1 192 ? -80.463 25.650  96.054  1.00 64.56  ? 267  LEU D CG  1 
ATOM   9820  C CD1 . LEU D 1 192 ? -81.975 25.807  96.005  1.00 77.31  ? 267  LEU D CD1 1 
ATOM   9821  C CD2 . LEU D 1 192 ? -79.958 25.015  94.774  1.00 96.36  ? 267  LEU D CD2 1 
ATOM   9822  N N   . LEU D 1 193 ? -77.814 29.276  97.289  1.00 73.55  ? 268  LEU D N   1 
ATOM   9823  C CA  . LEU D 1 193 ? -76.962 30.447  97.101  1.00 72.71  ? 268  LEU D CA  1 
ATOM   9824  C C   . LEU D 1 193 ? -75.514 30.152  97.485  1.00 80.09  ? 268  LEU D C   1 
ATOM   9825  O O   . LEU D 1 193 ? -74.578 30.532  96.766  1.00 82.25  ? 268  LEU D O   1 
ATOM   9826  C CB  . LEU D 1 193 ? -77.508 31.617  97.920  1.00 85.05  ? 268  LEU D CB  1 
ATOM   9827  C CG  . LEU D 1 193 ? -76.555 32.777  98.219  1.00 128.49 ? 268  LEU D CG  1 
ATOM   9828  C CD1 . LEU D 1 193 ? -76.321 33.604  96.966  1.00 130.08 ? 268  LEU D CD1 1 
ATOM   9829  C CD2 . LEU D 1 193 ? -77.086 33.643  99.353  1.00 116.75 ? 268  LEU D CD2 1 
ATOM   9830  N N   . GLN D 1 194 ? -75.307 29.471  98.615  1.00 72.32  ? 269  GLN D N   1 
ATOM   9831  C CA  . GLN D 1 194 ? -73.939 29.154  99.024  1.00 71.75  ? 269  GLN D CA  1 
ATOM   9832  C C   . GLN D 1 194 ? -73.263 28.197  98.047  1.00 73.09  ? 269  GLN D C   1 
ATOM   9833  O O   . GLN D 1 194 ? -72.065 28.335  97.754  1.00 78.15  ? 269  GLN D O   1 
ATOM   9834  C CB  . GLN D 1 194 ? -73.934 28.568  100.429 1.00 77.13  ? 269  GLN D CB  1 
ATOM   9835  C CG  . GLN D 1 194 ? -72.547 28.452  100.998 1.00 66.42  ? 269  GLN D CG  1 
ATOM   9836  C CD  . GLN D 1 194 ? -71.822 29.781  101.038 1.00 80.55  ? 269  GLN D CD  1 
ATOM   9837  O OE1 . GLN D 1 194 ? -70.778 29.946  100.410 1.00 93.25  ? 269  GLN D OE1 1 
ATOM   9838  N NE2 . GLN D 1 194 ? -72.371 30.737  101.781 1.00 96.83  ? 269  GLN D NE2 1 
ATOM   9839  N N   . LYS D 1 195 ? -74.007 27.203  97.559  1.00 66.02  ? 270  LYS D N   1 
ATOM   9840  C CA  . LYS D 1 195 ? -73.471 26.292  96.551  1.00 69.15  ? 270  LYS D CA  1 
ATOM   9841  C C   . LYS D 1 195 ? -73.066 27.054  95.295  1.00 70.85  ? 270  LYS D C   1 
ATOM   9842  O O   . LYS D 1 195 ? -72.021 26.775  94.692  1.00 65.43  ? 270  LYS D O   1 
ATOM   9843  C CB  . LYS D 1 195 ? -74.511 25.216  96.233  1.00 67.43  ? 270  LYS D CB  1 
ATOM   9844  C CG  . LYS D 1 195 ? -73.950 23.840  95.914  1.00 94.06  ? 270  LYS D CG  1 
ATOM   9845  C CD  . LYS D 1 195 ? -75.026 22.929  95.325  1.00 112.86 ? 270  LYS D CD  1 
ATOM   9846  C CE  . LYS D 1 195 ? -74.424 21.746  94.583  1.00 127.89 ? 270  LYS D CE  1 
ATOM   9847  N NZ  . LYS D 1 195 ? -73.703 22.183  93.356  1.00 98.26  ? 270  LYS D NZ  1 
ATOM   9848  N N   . ARG D 1 196 ? -73.888 28.028  94.892  1.00 77.79  ? 271  ARG D N   1 
ATOM   9849  C CA  . ARG D 1 196 ? -73.530 28.911  93.786  1.00 69.97  ? 271  ARG D CA  1 
ATOM   9850  C C   . ARG D 1 196 ? -72.221 29.643  94.059  1.00 72.54  ? 271  ARG D C   1 
ATOM   9851  O O   . ARG D 1 196 ? -71.366 29.755  93.172  1.00 81.40  ? 271  ARG D O   1 
ATOM   9852  C CB  . ARG D 1 196 ? -74.655 29.915  93.536  1.00 76.23  ? 271  ARG D CB  1 
ATOM   9853  C CG  . ARG D 1 196 ? -75.402 29.706  92.240  1.00 81.72  ? 271  ARG D CG  1 
ATOM   9854  C CD  . ARG D 1 196 ? -74.648 30.354  91.094  1.00 95.38  ? 271  ARG D CD  1 
ATOM   9855  N NE  . ARG D 1 196 ? -75.266 30.082  89.803  1.00 116.85 ? 271  ARG D NE  1 
ATOM   9856  C CZ  . ARG D 1 196 ? -74.894 30.645  88.662  1.00 112.42 ? 271  ARG D CZ  1 
ATOM   9857  N NH1 . ARG D 1 196 ? -73.887 31.502  88.610  1.00 109.21 ? 271  ARG D NH1 1 
ATOM   9858  N NH2 . ARG D 1 196 ? -75.547 30.340  87.544  1.00 113.93 ? 271  ARG D NH2 1 
ATOM   9859  N N   . LYS D 1 197 ? -72.057 30.165  95.276  1.00 68.90  ? 272  LYS D N   1 
ATOM   9860  C CA  . LYS D 1 197 ? -70.827 30.879  95.620  1.00 69.52  ? 272  LYS D CA  1 
ATOM   9861  C C   . LYS D 1 197 ? -69.606 29.972  95.481  1.00 78.99  ? 272  LYS D C   1 
ATOM   9862  O O   . LYS D 1 197 ? -68.577 30.364  94.908  1.00 74.79  ? 272  LYS D O   1 
ATOM   9863  C CB  . LYS D 1 197 ? -70.929 31.434  97.041  1.00 76.13  ? 272  LYS D CB  1 
ATOM   9864  C CG  . LYS D 1 197 ? -69.652 32.072  97.553  1.00 105.52 ? 272  LYS D CG  1 
ATOM   9865  C CD  . LYS D 1 197 ? -69.939 33.141  98.592  1.00 133.24 ? 272  LYS D CD  1 
ATOM   9866  C CE  . LYS D 1 197 ? -68.792 33.277  99.578  1.00 138.83 ? 272  LYS D CE  1 
ATOM   9867  N NZ  . LYS D 1 197 ? -68.638 32.067  100.433 1.00 156.54 ? 272  LYS D NZ  1 
ATOM   9868  N N   . GLU D 1 198 ? -69.709 28.746  95.997  1.00 76.51  ? 273  GLU D N   1 
ATOM   9869  C CA  . GLU D 1 198 ? -68.581 27.819  95.926  1.00 71.75  ? 273  GLU D CA  1 
ATOM   9870  C C   . GLU D 1 198 ? -68.266 27.443  94.480  1.00 68.47  ? 273  GLU D C   1 
ATOM   9871  O O   . GLU D 1 198 ? -67.091 27.349  94.088  1.00 75.20  ? 273  GLU D O   1 
ATOM   9872  C CB  . GLU D 1 198 ? -68.875 26.574  96.762  1.00 73.35  ? 273  GLU D CB  1 
ATOM   9873  C CG  . GLU D 1 198 ? -69.159 26.871  98.226  1.00 66.70  ? 273  GLU D CG  1 
ATOM   9874  C CD  . GLU D 1 198 ? -68.611 25.801  99.146  1.00 82.51  ? 273  GLU D CD  1 
ATOM   9875  O OE1 . GLU D 1 198 ? -68.436 26.080  100.352 1.00 69.44  ? 273  GLU D OE1 1 
ATOM   9876  O OE2 . GLU D 1 198 ? -68.349 24.682  98.658  1.00 104.63 ? 273  GLU D OE2 1 
ATOM   9877  N N   . LEU D 1 199 ? -69.307 27.233  93.670  1.00 65.54  ? 274  LEU D N   1 
ATOM   9878  C CA  . LEU D 1 199 ? -69.096 26.944  92.255  1.00 58.42  ? 274  LEU D CA  1 
ATOM   9879  C C   . LEU D 1 199 ? -68.426 28.114  91.544  1.00 62.95  ? 274  LEU D C   1 
ATOM   9880  O O   . LEU D 1 199 ? -67.589 27.914  90.656  1.00 76.54  ? 274  LEU D O   1 
ATOM   9881  C CB  . LEU D 1 199 ? -70.426 26.603  91.586  1.00 55.24  ? 274  LEU D CB  1 
ATOM   9882  C CG  . LEU D 1 199 ? -71.004 25.216  91.857  1.00 55.33  ? 274  LEU D CG  1 
ATOM   9883  C CD1 . LEU D 1 199 ? -72.258 25.001  91.027  1.00 61.15  ? 274  LEU D CD1 1 
ATOM   9884  C CD2 . LEU D 1 199 ? -69.970 24.146  91.563  1.00 62.41  ? 274  LEU D CD2 1 
ATOM   9885  N N   . GLN D 1 200 ? -68.783 29.345  91.917  1.00 58.13  ? 275  GLN D N   1 
ATOM   9886  C CA  . GLN D 1 200 ? -68.142 30.510  91.312  1.00 71.38  ? 275  GLN D CA  1 
ATOM   9887  C C   . GLN D 1 200 ? -66.665 30.578  91.677  1.00 73.30  ? 275  GLN D C   1 
ATOM   9888  O O   . GLN D 1 200 ? -65.828 30.951  90.845  1.00 71.30  ? 275  GLN D O   1 
ATOM   9889  C CB  . GLN D 1 200 ? -68.858 31.792  91.739  1.00 75.11  ? 275  GLN D CB  1 
ATOM   9890  C CG  . GLN D 1 200 ? -68.377 33.039  91.007  1.00 74.11  ? 275  GLN D CG  1 
ATOM   9891  C CD  . GLN D 1 200 ? -68.329 32.857  89.502  1.00 86.90  ? 275  GLN D CD  1 
ATOM   9892  O OE1 . GLN D 1 200 ? -69.365 32.731  88.849  1.00 95.10  ? 275  GLN D OE1 1 
ATOM   9893  N NE2 . GLN D 1 200 ? -67.124 32.849  88.943  1.00 98.19  ? 275  GLN D NE2 1 
ATOM   9894  N N   . GLU D 1 201 ? -66.324 30.231  92.921  1.00 69.32  ? 276  GLU D N   1 
ATOM   9895  C CA  . GLU D 1 201 ? -64.910 30.174  93.291  1.00 75.57  ? 276  GLU D CA  1 
ATOM   9896  C C   . GLU D 1 201 ? -64.163 29.121  92.473  1.00 71.54  ? 276  GLU D C   1 
ATOM   9897  O O   . GLU D 1 201 ? -63.045 29.370  91.990  1.00 76.23  ? 276  GLU D O   1 
ATOM   9898  C CB  . GLU D 1 201 ? -64.760 29.902  94.788  1.00 81.86  ? 276  GLU D CB  1 
ATOM   9899  C CG  . GLU D 1 201 ? -65.327 30.993  95.685  1.00 79.84  ? 276  GLU D CG  1 
ATOM   9900  C CD  . GLU D 1 201 ? -65.865 30.459  96.998  1.00 89.30  ? 276  GLU D CD  1 
ATOM   9901  O OE1 . GLU D 1 201 ? -65.507 29.323  97.373  1.00 92.86  ? 276  GLU D OE1 1 
ATOM   9902  O OE2 . GLU D 1 201 ? -66.623 31.188  97.669  1.00 106.73 ? 276  GLU D OE2 1 
ATOM   9903  N N   . ASN D 1 202 ? -64.763 27.938  92.307  1.00 65.09  ? 277  ASN D N   1 
ATOM   9904  C CA  . ASN D 1 202 ? -64.150 26.916  91.457  1.00 70.60  ? 277  ASN D CA  1 
ATOM   9905  C C   . ASN D 1 202 ? -63.956 27.428  90.032  1.00 73.39  ? 277  ASN D C   1 
ATOM   9906  O O   . ASN D 1 202 ? -62.922 27.164  89.399  1.00 65.87  ? 277  ASN D O   1 
ATOM   9907  C CB  . ASN D 1 202 ? -64.999 25.644  91.449  1.00 56.86  ? 277  ASN D CB  1 
ATOM   9908  C CG  . ASN D 1 202 ? -65.181 25.050  92.831  1.00 69.79  ? 277  ASN D CG  1 
ATOM   9909  O OD1 . ASN D 1 202 ? -64.240 24.985  93.621  1.00 85.00  ? 277  ASN D OD1 1 
ATOM   9910  N ND2 . ASN D 1 202 ? -66.396 24.600  93.125  1.00 87.87  ? 277  ASN D ND2 1 
ATOM   9911  N N   . GLN D 1 203 ? -64.951 28.150  89.507  1.00 69.83  ? 278  GLN D N   1 
ATOM   9912  C CA  . GLN D 1 203 ? -64.846 28.680  88.152  1.00 69.37  ? 278  GLN D CA  1 
ATOM   9913  C C   . GLN D 1 203 ? -63.707 29.679  88.046  1.00 70.61  ? 278  GLN D C   1 
ATOM   9914  O O   . GLN D 1 203 ? -62.974 29.688  87.053  1.00 71.85  ? 278  GLN D O   1 
ATOM   9915  C CB  . GLN D 1 203 ? -66.155 29.343  87.726  1.00 79.24  ? 278  GLN D CB  1 
ATOM   9916  C CG  . GLN D 1 203 ? -66.450 29.203  86.241  1.00 87.33  ? 278  GLN D CG  1 
ATOM   9917  C CD  . GLN D 1 203 ? -67.700 29.947  85.806  1.00 100.86 ? 278  GLN D CD  1 
ATOM   9918  O OE1 . GLN D 1 203 ? -68.562 30.274  86.619  1.00 105.35 ? 278  GLN D OE1 1 
ATOM   9919  N NE2 . GLN D 1 203 ? -67.815 30.192  84.506  1.00 113.43 ? 278  GLN D NE2 1 
ATOM   9920  N N   . ASP D 1 204 ? -63.551 30.539  89.056  1.00 70.73  ? 279  ASP D N   1 
ATOM   9921  C CA  . ASP D 1 204 ? -62.444 31.493  89.045  1.00 67.58  ? 279  ASP D CA  1 
ATOM   9922  C C   . ASP D 1 204 ? -61.100 30.778  89.067  1.00 63.53  ? 279  ASP D C   1 
ATOM   9923  O O   . ASP D 1 204 ? -60.150 31.206  88.401  1.00 70.73  ? 279  ASP D O   1 
ATOM   9924  C CB  . ASP D 1 204 ? -62.549 32.457  90.226  1.00 78.03  ? 279  ASP D CB  1 
ATOM   9925  C CG  . ASP D 1 204 ? -63.848 33.230  90.233  1.00 85.74  ? 279  ASP D CG  1 
ATOM   9926  O OD1 . ASP D 1 204 ? -64.340 33.565  89.135  1.00 71.15  ? 279  ASP D OD1 1 
ATOM   9927  O OD2 . ASP D 1 204 ? -64.368 33.509  91.335  1.00 87.14  ? 279  ASP D OD2 1 
ATOM   9928  N N   . GLU D 1 205 ? -61.000 29.685  89.825  1.00 70.19  ? 280  GLU D N   1 
ATOM   9929  C CA  . GLU D 1 205 ? -59.732 28.961  89.887  1.00 75.93  ? 280  GLU D CA  1 
ATOM   9930  C C   . GLU D 1 205 ? -59.400 28.327  88.537  1.00 74.12  ? 280  GLU D C   1 
ATOM   9931  O O   . GLU D 1 205 ? -58.272 28.453  88.028  1.00 80.94  ? 280  GLU D O   1 
ATOM   9932  C CB  . GLU D 1 205 ? -59.799 27.904  90.990  1.00 69.73  ? 280  GLU D CB  1 
ATOM   9933  C CG  . GLU D 1 205 ? -59.650 28.495  92.382  1.00 89.87  ? 280  GLU D CG  1 
ATOM   9934  C CD  . GLU D 1 205 ? -58.211 28.693  92.805  1.00 101.55 ? 280  GLU D CD  1 
ATOM   9935  O OE1 . GLU D 1 205 ? -57.951 28.627  94.022  1.00 119.71 ? 280  GLU D OE1 1 
ATOM   9936  O OE2 . GLU D 1 205 ? -57.341 28.903  91.933  1.00 106.89 ? 280  GLU D OE2 1 
ATOM   9937  N N   . ILE D 1 206 ? -60.383 27.650  87.937  1.00 65.44  ? 281  ILE D N   1 
ATOM   9938  C CA  . ILE D 1 206 ? -60.191 27.071  86.611  1.00 48.31  ? 281  ILE D CA  1 
ATOM   9939  C C   . ILE D 1 206 ? -59.878 28.158  85.589  1.00 60.75  ? 281  ILE D C   1 
ATOM   9940  O O   . ILE D 1 206 ? -59.089 27.941  84.660  1.00 69.55  ? 281  ILE D O   1 
ATOM   9941  C CB  . ILE D 1 206 ? -61.428 26.240  86.213  1.00 56.89  ? 281  ILE D CB  1 
ATOM   9942  C CG1 . ILE D 1 206 ? -61.611 25.061  87.171  1.00 63.06  ? 281  ILE D CG1 1 
ATOM   9943  C CG2 . ILE D 1 206 ? -61.304 25.727  84.788  1.00 54.23  ? 281  ILE D CG2 1 
ATOM   9944  C CD1 . ILE D 1 206 ? -60.420 24.123  87.220  1.00 48.81  ? 281  ILE D CD1 1 
ATOM   9945  N N   . GLU D 1 207 ? -60.461 29.349  85.753  1.00 60.64  ? 282  GLU D N   1 
ATOM   9946  C CA  . GLU D 1 207 ? -60.181 30.444  84.832  1.00 62.50  ? 282  GLU D CA  1 
ATOM   9947  C C   . GLU D 1 207 ? -58.748 30.938  84.971  1.00 65.85  ? 282  GLU D C   1 
ATOM   9948  O O   . GLU D 1 207 ? -58.101 31.256  83.968  1.00 74.14  ? 282  GLU D O   1 
ATOM   9949  C CB  . GLU D 1 207 ? -61.155 31.598  85.061  1.00 72.19  ? 282  GLU D CB  1 
ATOM   9950  C CG  . GLU D 1 207 ? -61.097 32.656  83.976  1.00 78.92  ? 282  GLU D CG  1 
ATOM   9951  C CD  . GLU D 1 207 ? -62.284 33.592  84.009  1.00 105.09 ? 282  GLU D CD  1 
ATOM   9952  O OE1 . GLU D 1 207 ? -62.267 34.597  83.267  1.00 112.51 ? 282  GLU D OE1 1 
ATOM   9953  O OE2 . GLU D 1 207 ? -63.230 33.324  84.778  1.00 111.49 ? 282  GLU D OE2 1 
ATOM   9954  N N   . ASN D 1 208 ? -58.246 31.039  86.205  1.00 73.61  ? 283  ASN D N   1 
ATOM   9955  C CA  . ASN D 1 208 ? -56.837 31.375  86.399  1.00 60.96  ? 283  ASN D CA  1 
ATOM   9956  C C   . ASN D 1 208 ? -55.939 30.370  85.692  1.00 63.51  ? 283  ASN D C   1 
ATOM   9957  O O   . ASN D 1 208 ? -55.010 30.750  84.972  1.00 73.27  ? 283  ASN D O   1 
ATOM   9958  C CB  . ASN D 1 208 ? -56.492 31.445  87.888  1.00 67.07  ? 283  ASN D CB  1 
ATOM   9959  C CG  . ASN D 1 208 ? -56.919 32.750  88.529  1.00 105.04 ? 283  ASN D CG  1 
ATOM   9960  O OD1 . ASN D 1 208 ? -57.774 33.465  88.008  1.00 118.00 ? 283  ASN D OD1 1 
ATOM   9961  N ND2 . ASN D 1 208 ? -56.311 33.072  89.667  1.00 118.83 ? 283  ASN D ND2 1 
ATOM   9962  N N   . MET D 1 209 ? -56.213 29.076  85.881  1.00 64.07  ? 284  MET D N   1 
ATOM   9963  C CA  . MET D 1 209 ? -55.405 28.049  85.223  1.00 57.43  ? 284  MET D CA  1 
ATOM   9964  C C   . MET D 1 209 ? -55.451 28.196  83.702  1.00 56.18  ? 284  MET D C   1 
ATOM   9965  O O   . MET D 1 209 ? -54.411 28.179  83.027  1.00 60.84  ? 284  MET D O   1 
ATOM   9966  C CB  . MET D 1 209 ? -55.893 26.667  85.649  1.00 52.65  ? 284  MET D CB  1 
ATOM   9967  C CG  . MET D 1 209 ? -55.870 26.459  87.149  1.00 50.24  ? 284  MET D CG  1 
ATOM   9968  S SD  . MET D 1 209 ? -56.653 24.914  87.631  1.00 63.06  ? 284  MET D SD  1 
ATOM   9969  C CE  . MET D 1 209 ? -57.164 25.303  89.302  1.00 83.56  ? 284  MET D CE  1 
ATOM   9970  N N   . MET D 1 210 ? -56.658 28.350  83.151  1.00 59.32  ? 285  MET D N   1 
ATOM   9971  C CA  . MET D 1 210 ? -56.833 28.421  81.704  1.00 63.19  ? 285  MET D CA  1 
ATOM   9972  C C   . MET D 1 210 ? -56.142 29.649  81.122  1.00 67.93  ? 285  MET D C   1 
ATOM   9973  O O   . MET D 1 210 ? -55.462 29.565  80.091  1.00 64.07  ? 285  MET D O   1 
ATOM   9974  C CB  . MET D 1 210 ? -58.327 28.432  81.375  1.00 56.46  ? 285  MET D CB  1 
ATOM   9975  C CG  . MET D 1 210 ? -58.958 27.054  81.243  1.00 59.49  ? 285  MET D CG  1 
ATOM   9976  S SD  . MET D 1 210 ? -60.677 27.140  80.708  1.00 62.82  ? 285  MET D SD  1 
ATOM   9977  C CE  . MET D 1 210 ? -61.143 28.758  81.319  1.00 70.39  ? 285  MET D CE  1 
ATOM   9978  N N   . ASN D 1 211 ? -56.312 30.805  81.770  1.00 66.97  ? 286  ASN D N   1 
ATOM   9979  C CA  . ASN D 1 211 ? -55.692 32.034  81.288  1.00 67.93  ? 286  ASN D CA  1 
ATOM   9980  C C   . ASN D 1 211 ? -54.178 31.960  81.397  1.00 69.95  ? 286  ASN D C   1 
ATOM   9981  O O   . ASN D 1 211 ? -53.461 32.486  80.538  1.00 79.72  ? 286  ASN D O   1 
ATOM   9982  C CB  . ASN D 1 211 ? -56.219 33.231  82.078  1.00 61.49  ? 286  ASN D CB  1 
ATOM   9983  C CG  . ASN D 1 211 ? -57.366 33.933  81.382  1.00 106.35 ? 286  ASN D CG  1 
ATOM   9984  O OD1 . ASN D 1 211 ? -57.522 33.843  80.164  1.00 117.58 ? 286  ASN D OD1 1 
ATOM   9985  N ND2 . ASN D 1 211 ? -58.181 34.637  82.159  1.00 114.45 ? 286  ASN D ND2 1 
ATOM   9986  N N   . ALA D 1 212 ? -53.671 31.316  82.450  1.00 55.16  ? 287  ALA D N   1 
ATOM   9987  C CA  . ALA D 1 212 ? -52.234 31.111  82.568  1.00 46.84  ? 287  ALA D CA  1 
ATOM   9988  C C   . ALA D 1 212 ? -51.709 30.292  81.399  1.00 50.31  ? 287  ALA D C   1 
ATOM   9989  O O   . ALA D 1 212 ? -50.705 30.653  80.775  1.00 58.60  ? 287  ALA D O   1 
ATOM   9990  C CB  . ALA D 1 212 ? -51.911 30.431  83.898  1.00 51.65  ? 287  ALA D CB  1 
ATOM   9991  N N   . ILE D 1 213 ? -52.391 29.192  81.072  1.00 59.14  ? 288  ILE D N   1 
ATOM   9992  C CA  . ILE D 1 213 ? -51.938 28.368  79.952  1.00 54.22  ? 288  ILE D CA  1 
ATOM   9993  C C   . ILE D 1 213 ? -52.011 29.147  78.643  1.00 53.95  ? 288  ILE D C   1 
ATOM   9994  O O   . ILE D 1 213 ? -51.081 29.103  77.829  1.00 57.75  ? 288  ILE D O   1 
ATOM   9995  C CB  . ILE D 1 213 ? -52.741 27.057  79.877  1.00 64.66  ? 288  ILE D CB  1 
ATOM   9996  C CG1 . ILE D 1 213 ? -52.432 26.181  81.092  1.00 59.44  ? 288  ILE D CG1 1 
ATOM   9997  C CG2 . ILE D 1 213 ? -52.433 26.313  78.581  1.00 44.30  ? 288  ILE D CG2 1 
ATOM   9998  C CD1 . ILE D 1 213 ? -52.672 24.710  80.855  1.00 45.58  ? 288  ILE D CD1 1 
ATOM   9999  N N   . PHE D 1 214 ? -53.103 29.884  78.424  1.00 54.11  ? 289  PHE D N   1 
ATOM   10000 C CA  . PHE D 1 214 ? -53.272 30.587  77.154  1.00 59.84  ? 289  PHE D CA  1 
ATOM   10001 C C   . PHE D 1 214 ? -52.243 31.701  76.991  1.00 63.90  ? 289  PHE D C   1 
ATOM   10002 O O   . PHE D 1 214 ? -51.532 31.760  75.980  1.00 64.37  ? 289  PHE D O   1 
ATOM   10003 C CB  . PHE D 1 214 ? -54.688 31.151  77.043  1.00 50.83  ? 289  PHE D CB  1 
ATOM   10004 C CG  . PHE D 1 214 ? -55.015 31.687  75.677  1.00 65.21  ? 289  PHE D CG  1 
ATOM   10005 C CD1 . PHE D 1 214 ? -55.418 30.837  74.661  1.00 63.33  ? 289  PHE D CD1 1 
ATOM   10006 C CD2 . PHE D 1 214 ? -54.889 33.039  75.404  1.00 61.84  ? 289  PHE D CD2 1 
ATOM   10007 C CE1 . PHE D 1 214 ? -55.714 31.329  73.404  1.00 60.19  ? 289  PHE D CE1 1 
ATOM   10008 C CE2 . PHE D 1 214 ? -55.178 33.538  74.149  1.00 46.94  ? 289  PHE D CE2 1 
ATOM   10009 C CZ  . PHE D 1 214 ? -55.590 32.682  73.148  1.00 55.55  ? 289  PHE D CZ  1 
ATOM   10010 N N   . LYS D 1 215 ? -52.152 32.600  77.977  1.00 62.58  ? 290  LYS D N   1 
ATOM   10011 C CA  . LYS D 1 215 ? -51.260 33.748  77.874  1.00 65.97  ? 290  LYS D CA  1 
ATOM   10012 C C   . LYS D 1 215 ? -49.798 33.368  78.059  1.00 66.24  ? 290  LYS D C   1 
ATOM   10013 O O   . LYS D 1 215 ? -48.915 34.164  77.720  1.00 58.18  ? 290  LYS D O   1 
ATOM   10014 C CB  . LYS D 1 215 ? -51.652 34.801  78.910  1.00 59.14  ? 290  LYS D CB  1 
ATOM   10015 C CG  . LYS D 1 215 ? -52.559 35.893  78.381  1.00 75.88  ? 290  LYS D CG  1 
ATOM   10016 C CD  . LYS D 1 215 ? -53.048 36.793  79.506  1.00 92.34  ? 290  LYS D CD  1 
ATOM   10017 C CE  . LYS D 1 215 ? -54.447 36.406  79.953  1.00 85.50  ? 290  LYS D CE  1 
ATOM   10018 N NZ  . LYS D 1 215 ? -54.875 37.158  81.164  1.00 78.08  ? 290  LYS D NZ  1 
ATOM   10019 N N   . GLY D 1 216 ? -49.519 32.184  78.598  1.00 63.62  ? 291  GLY D N   1 
ATOM   10020 C CA  . GLY D 1 216 ? -48.147 31.801  78.856  1.00 55.85  ? 291  GLY D CA  1 
ATOM   10021 C C   . GLY D 1 216 ? -47.566 30.874  77.813  1.00 57.30  ? 291  GLY D C   1 
ATOM   10022 O O   . GLY D 1 216 ? -46.344 30.817  77.644  1.00 66.23  ? 291  GLY D O   1 
ATOM   10023 N N   . VAL D 1 217 ? -48.423 30.144  77.099  1.00 54.00  ? 292  VAL D N   1 
ATOM   10024 C CA  . VAL D 1 217 ? -47.992 29.155  76.118  1.00 42.33  ? 292  VAL D CA  1 
ATOM   10025 C C   . VAL D 1 217 ? -48.539 29.462  74.728  1.00 50.72  ? 292  VAL D C   1 
ATOM   10026 O O   . VAL D 1 217 ? -47.778 29.561  73.761  1.00 60.98  ? 292  VAL D O   1 
ATOM   10027 C CB  . VAL D 1 217 ? -48.378 27.724  76.552  1.00 36.13  ? 292  VAL D CB  1 
ATOM   10028 C CG1 . VAL D 1 217 ? -47.930 26.719  75.506  1.00 55.87  ? 292  VAL D CG1 1 
ATOM   10029 C CG2 . VAL D 1 217 ? -47.761 27.400  77.899  1.00 35.83  ? 292  VAL D CG2 1 
ATOM   10030 N N   . PHE D 1 218 ? -49.862 29.614  74.606  1.00 43.10  ? 293  PHE D N   1 
ATOM   10031 C CA  . PHE D 1 218 ? -50.464 29.698  73.276  1.00 44.35  ? 293  PHE D CA  1 
ATOM   10032 C C   . PHE D 1 218 ? -49.964 30.916  72.509  1.00 51.80  ? 293  PHE D C   1 
ATOM   10033 O O   . PHE D 1 218 ? -49.520 30.799  71.361  1.00 59.03  ? 293  PHE D O   1 
ATOM   10034 C CB  . PHE D 1 218 ? -51.989 29.726  73.361  1.00 44.85  ? 293  PHE D CB  1 
ATOM   10035 C CG  . PHE D 1 218 ? -52.649 29.822  72.015  1.00 48.36  ? 293  PHE D CG  1 
ATOM   10036 C CD1 . PHE D 1 218 ? -52.903 28.680  71.273  1.00 52.11  ? 293  PHE D CD1 1 
ATOM   10037 C CD2 . PHE D 1 218 ? -52.974 31.056  71.469  1.00 51.25  ? 293  PHE D CD2 1 
ATOM   10038 C CE1 . PHE D 1 218 ? -53.490 28.765  70.024  1.00 63.37  ? 293  PHE D CE1 1 
ATOM   10039 C CE2 . PHE D 1 218 ? -53.561 31.148  70.220  1.00 49.58  ? 293  PHE D CE2 1 
ATOM   10040 C CZ  . PHE D 1 218 ? -53.817 30.001  69.495  1.00 50.29  ? 293  PHE D CZ  1 
ATOM   10041 N N   . VAL D 1 219 ? -50.044 32.102  73.120  1.00 47.92  ? 294  VAL D N   1 
ATOM   10042 C CA  . VAL D 1 219 ? -49.664 33.323  72.419  1.00 52.50  ? 294  VAL D CA  1 
ATOM   10043 C C   . VAL D 1 219 ? -48.199 33.303  72.014  1.00 63.58  ? 294  VAL D C   1 
ATOM   10044 O O   . VAL D 1 219 ? -47.790 34.063  71.129  1.00 64.46  ? 294  VAL D O   1 
ATOM   10045 C CB  . VAL D 1 219 ? -49.973 34.560  73.285  1.00 46.29  ? 294  VAL D CB  1 
ATOM   10046 C CG1 . VAL D 1 219 ? -51.470 34.721  73.457  1.00 44.45  ? 294  VAL D CG1 1 
ATOM   10047 C CG2 . VAL D 1 219 ? -49.281 34.452  74.628  1.00 67.93  ? 294  VAL D CG2 1 
ATOM   10048 N N   . HIS D 1 220 ? -47.395 32.446  72.643  1.00 57.26  ? 295  HIS D N   1 
ATOM   10049 C CA  . HIS D 1 220 ? -45.998 32.273  72.271  1.00 56.61  ? 295  HIS D CA  1 
ATOM   10050 C C   . HIS D 1 220 ? -45.802 31.161  71.251  1.00 55.20  ? 295  HIS D C   1 
ATOM   10051 O O   . HIS D 1 220 ? -44.957 31.285  70.358  1.00 63.61  ? 295  HIS D O   1 
ATOM   10052 C CB  . HIS D 1 220 ? -45.161 31.971  73.516  1.00 63.28  ? 295  HIS D CB  1 
ATOM   10053 C CG  . HIS D 1 220 ? -45.237 33.032  74.566  1.00 76.46  ? 295  HIS D CG  1 
ATOM   10054 N ND1 . HIS D 1 220 ? -45.864 32.838  75.778  1.00 89.40  ? 295  HIS D ND1 1 
ATOM   10055 C CD2 . HIS D 1 220 ? -44.756 34.297  74.589  1.00 75.10  ? 295  HIS D CD2 1 
ATOM   10056 C CE1 . HIS D 1 220 ? -45.771 33.939  76.501  1.00 90.60  ? 295  HIS D CE1 1 
ATOM   10057 N NE2 . HIS D 1 220 ? -45.104 34.840  75.802  1.00 89.32  ? 295  HIS D NE2 1 
ATOM   10058 N N   . ARG D 1 221 ? -46.567 30.077  71.365  1.00 53.34  ? 296  ARG D N   1 
ATOM   10059 C CA  . ARG D 1 221 ? -46.337 28.901  70.539  1.00 57.76  ? 296  ARG D CA  1 
ATOM   10060 C C   . ARG D 1 221 ? -47.190 28.864  69.278  1.00 60.28  ? 296  ARG D C   1 
ATOM   10061 O O   . ARG D 1 221 ? -46.859 28.119  68.349  1.00 61.34  ? 296  ARG D O   1 
ATOM   10062 C CB  . ARG D 1 221 ? -46.579 27.628  71.357  1.00 52.89  ? 296  ARG D CB  1 
ATOM   10063 C CG  . ARG D 1 221 ? -45.618 27.418  72.517  1.00 50.26  ? 296  ARG D CG  1 
ATOM   10064 C CD  . ARG D 1 221 ? -44.167 27.408  72.056  1.00 54.84  ? 296  ARG D CD  1 
ATOM   10065 N NE  . ARG D 1 221 ? -43.394 28.488  72.657  1.00 57.52  ? 296  ARG D NE  1 
ATOM   10066 C CZ  . ARG D 1 221 ? -42.551 29.269  71.997  1.00 61.64  ? 296  ARG D CZ  1 
ATOM   10067 N NH1 . ARG D 1 221 ? -42.357 29.132  70.696  1.00 66.11  ? 296  ARG D NH1 1 
ATOM   10068 N NH2 . ARG D 1 221 ? -41.883 30.209  72.660  1.00 72.59  ? 296  ARG D NH2 1 
ATOM   10069 N N   . TYR D 1 222 ? -48.280 29.634  69.217  1.00 59.83  ? 297  TYR D N   1 
ATOM   10070 C CA  . TYR D 1 222 ? -49.028 29.732  67.968  1.00 53.89  ? 297  TYR D CA  1 
ATOM   10071 C C   . TYR D 1 222 ? -48.207 30.399  66.875  1.00 62.40  ? 297  TYR D C   1 
ATOM   10072 O O   . TYR D 1 222 ? -48.529 30.254  65.691  1.00 64.16  ? 297  TYR D O   1 
ATOM   10073 C CB  . TYR D 1 222 ? -50.333 30.502  68.184  1.00 42.60  ? 297  TYR D CB  1 
ATOM   10074 C CG  . TYR D 1 222 ? -50.232 31.982  67.884  1.00 55.17  ? 297  TYR D CG  1 
ATOM   10075 C CD1 . TYR D 1 222 ? -49.721 32.869  68.824  1.00 54.52  ? 297  TYR D CD1 1 
ATOM   10076 C CD2 . TYR D 1 222 ? -50.656 32.493  66.662  1.00 55.06  ? 297  TYR D CD2 1 
ATOM   10077 C CE1 . TYR D 1 222 ? -49.630 34.223  68.554  1.00 55.01  ? 297  TYR D CE1 1 
ATOM   10078 C CE2 . TYR D 1 222 ? -50.568 33.841  66.384  1.00 57.80  ? 297  TYR D CE2 1 
ATOM   10079 C CZ  . TYR D 1 222 ? -50.055 34.702  67.332  1.00 62.94  ? 297  TYR D CZ  1 
ATOM   10080 O OH  . TYR D 1 222 ? -49.969 36.046  67.053  1.00 67.69  ? 297  TYR D OH  1 
ATOM   10081 N N   . ARG D 1 223 ? -47.163 31.134  67.254  1.00 54.28  ? 298  ARG D N   1 
ATOM   10082 C CA  . ARG D 1 223 ? -46.248 31.787  66.329  1.00 55.02  ? 298  ARG D CA  1 
ATOM   10083 C C   . ARG D 1 223 ? -44.852 31.180  66.417  1.00 61.83  ? 298  ARG D C   1 
ATOM   10084 O O   . ARG D 1 223 ? -43.854 31.847  66.137  1.00 70.78  ? 298  ARG D O   1 
ATOM   10085 C CB  . ARG D 1 223 ? -46.217 33.289  66.606  1.00 48.43  ? 298  ARG D CB  1 
ATOM   10086 C CG  . ARG D 1 223 ? -45.981 33.624  68.068  1.00 58.99  ? 298  ARG D CG  1 
ATOM   10087 C CD  . ARG D 1 223 ? -46.149 35.111  68.350  1.00 81.80  ? 298  ARG D CD  1 
ATOM   10088 N NE  . ARG D 1 223 ? -45.041 35.913  67.848  1.00 77.60  ? 298  ARG D NE  1 
ATOM   10089 C CZ  . ARG D 1 223 ? -45.007 37.238  67.880  1.00 74.74  ? 298  ARG D CZ  1 
ATOM   10090 N NH1 . ARG D 1 223 ? -46.006 37.943  68.385  1.00 83.24  ? 298  ARG D NH1 1 
ATOM   10091 N NH2 . ARG D 1 223 ? -43.943 37.871  67.395  1.00 76.32  ? 298  ARG D NH2 1 
ATOM   10092 N N   . ASP D 1 224 ? -44.781 29.911  66.816  1.00 61.07  ? 299  ASP D N   1 
ATOM   10093 C CA  . ASP D 1 224 ? -43.506 29.224  66.961  1.00 56.95  ? 299  ASP D CA  1 
ATOM   10094 C C   . ASP D 1 224 ? -42.793 29.127  65.619  1.00 68.67  ? 299  ASP D C   1 
ATOM   10095 O O   . ASP D 1 224 ? -43.418 29.120  64.555  1.00 67.09  ? 299  ASP D O   1 
ATOM   10096 C CB  . ASP D 1 224 ? -43.723 27.825  67.541  1.00 58.89  ? 299  ASP D CB  1 
ATOM   10097 C CG  . ASP D 1 224 ? -42.447 27.211  68.079  1.00 70.40  ? 299  ASP D CG  1 
ATOM   10098 O OD1 . ASP D 1 224 ? -41.621 26.744  67.265  1.00 66.12  ? 299  ASP D OD1 1 
ATOM   10099 O OD2 . ASP D 1 224 ? -42.272 27.189  69.316  1.00 75.67  ? 299  ASP D OD2 1 
ATOM   10100 N N   . ALA D 1 225 ? -41.462 29.054  65.676  1.00 73.66  ? 300  ALA D N   1 
ATOM   10101 C CA  . ALA D 1 225 ? -40.685 28.901  64.451  1.00 66.82  ? 300  ALA D CA  1 
ATOM   10102 C C   . ALA D 1 225 ? -40.998 27.578  63.766  1.00 64.73  ? 300  ALA D C   1 
ATOM   10103 O O   . ALA D 1 225 ? -41.071 27.509  62.533  1.00 63.15  ? 300  ALA D O   1 
ATOM   10104 C CB  . ALA D 1 225 ? -39.193 29.010  64.758  1.00 65.14  ? 300  ALA D CB  1 
ATOM   10105 N N   . ILE D 1 226 ? -41.199 26.523  64.548  1.00 65.98  ? 301  ILE D N   1 
ATOM   10106 C CA  . ILE D 1 226 ? -41.509 25.206  64.001  1.00 62.03  ? 301  ILE D CA  1 
ATOM   10107 C C   . ILE D 1 226 ? -42.989 25.147  63.649  1.00 72.91  ? 301  ILE D C   1 
ATOM   10108 O O   . ILE D 1 226 ? -43.850 25.524  64.454  1.00 76.51  ? 301  ILE D O   1 
ATOM   10109 C CB  . ILE D 1 226 ? -41.125 24.101  64.999  1.00 62.88  ? 301  ILE D CB  1 
ATOM   10110 C CG1 . ILE D 1 226 ? -39.641 24.199  65.365  1.00 56.38  ? 301  ILE D CG1 1 
ATOM   10111 C CG2 . ILE D 1 226 ? -41.446 22.730  64.426  1.00 69.24  ? 301  ILE D CG2 1 
ATOM   10112 C CD1 . ILE D 1 226 ? -38.740 24.542  64.196  1.00 69.75  ? 301  ILE D CD1 1 
ATOM   10113 N N   . ALA D 1 227 ? -43.291 24.670  62.439  1.00 70.38  ? 302  ALA D N   1 
ATOM   10114 C CA  . ALA D 1 227 ? -44.677 24.623  61.985  1.00 65.92  ? 302  ALA D CA  1 
ATOM   10115 C C   . ALA D 1 227 ? -45.501 23.608  62.770  1.00 65.49  ? 302  ALA D C   1 
ATOM   10116 O O   . ALA D 1 227 ? -46.710 23.800  62.945  1.00 74.05  ? 302  ALA D O   1 
ATOM   10117 C CB  . ALA D 1 227 ? -44.727 24.307  60.490  1.00 71.58  ? 302  ALA D CB  1 
ATOM   10118 N N   . GLU D 1 228 ? -44.869 22.527  63.238  1.00 69.08  ? 303  GLU D N   1 
ATOM   10119 C CA  . GLU D 1 228 ? -45.576 21.517  64.025  1.00 67.91  ? 303  GLU D CA  1 
ATOM   10120 C C   . GLU D 1 228 ? -46.237 22.133  65.253  1.00 67.68  ? 303  GLU D C   1 
ATOM   10121 O O   . GLU D 1 228 ? -47.416 21.882  65.539  1.00 73.54  ? 303  GLU D O   1 
ATOM   10122 C CB  . GLU D 1 228 ? -44.600 20.413  64.442  1.00 82.18  ? 303  GLU D CB  1 
ATOM   10123 C CG  . GLU D 1 228 ? -44.133 19.506  63.313  1.00 112.79 ? 303  GLU D CG  1 
ATOM   10124 C CD  . GLU D 1 228 ? -45.082 18.344  63.085  1.00 126.40 ? 303  GLU D CD  1 
ATOM   10125 O OE1 . GLU D 1 228 ? -45.348 17.606  64.057  1.00 95.82  ? 303  GLU D OE1 1 
ATOM   10126 O OE2 . GLU D 1 228 ? -45.561 18.167  61.944  1.00 133.52 ? 303  GLU D OE2 1 
ATOM   10127 N N   . ILE D 1 229 ? -45.481 22.945  65.991  1.00 56.02  ? 304  ILE D N   1 
ATOM   10128 C CA  . ILE D 1 229 ? -45.979 23.542  67.226  1.00 63.11  ? 304  ILE D CA  1 
ATOM   10129 C C   . ILE D 1 229 ? -47.134 24.493  66.928  1.00 56.36  ? 304  ILE D C   1 
ATOM   10130 O O   . ILE D 1 229 ? -48.162 24.494  67.625  1.00 70.67  ? 304  ILE D O   1 
ATOM   10131 C CB  . ILE D 1 229 ? -44.816 24.243  67.953  1.00 60.91  ? 304  ILE D CB  1 
ATOM   10132 C CG1 . ILE D 1 229 ? -43.604 23.305  67.997  1.00 51.14  ? 304  ILE D CG1 1 
ATOM   10133 C CG2 . ILE D 1 229 ? -45.222 24.665  69.354  1.00 51.42  ? 304  ILE D CG2 1 
ATOM   10134 C CD1 . ILE D 1 229 ? -42.595 23.630  69.074  1.00 57.97  ? 304  ILE D CD1 1 
ATOM   10135 N N   . ARG D 1 230 ? -46.989 25.305  65.876  1.00 46.95  ? 305  ARG D N   1 
ATOM   10136 C CA  . ARG D 1 230 ? -48.062 26.212  65.480  1.00 54.17  ? 305  ARG D CA  1 
ATOM   10137 C C   . ARG D 1 230 ? -49.328 25.445  65.127  1.00 60.70  ? 305  ARG D C   1 
ATOM   10138 O O   . ARG D 1 230 ? -50.434 25.852  65.502  1.00 61.57  ? 305  ARG D O   1 
ATOM   10139 C CB  . ARG D 1 230 ? -47.628 27.064  64.288  1.00 54.43  ? 305  ARG D CB  1 
ATOM   10140 C CG  . ARG D 1 230 ? -46.472 28.002  64.550  1.00 61.81  ? 305  ARG D CG  1 
ATOM   10141 C CD  . ARG D 1 230 ? -46.340 29.008  63.414  1.00 63.00  ? 305  ARG D CD  1 
ATOM   10142 N NE  . ARG D 1 230 ? -46.152 28.367  62.116  1.00 63.92  ? 305  ARG D NE  1 
ATOM   10143 C CZ  . ARG D 1 230 ? -44.975 28.173  61.536  1.00 65.21  ? 305  ARG D CZ  1 
ATOM   10144 N NH1 . ARG D 1 230 ? -43.845 28.528  62.127  1.00 64.22  ? 305  ARG D NH1 1 
ATOM   10145 N NH2 . ARG D 1 230 ? -44.931 27.615  60.330  1.00 74.13  ? 305  ARG D NH2 1 
ATOM   10146 N N   . ALA D 1 231 ? -49.184 24.343  64.387  1.00 62.34  ? 306  ALA D N   1 
ATOM   10147 C CA  . ALA D 1 231 ? -50.347 23.553  64.000  1.00 56.54  ? 306  ALA D CA  1 
ATOM   10148 C C   . ALA D 1 231 ? -51.035 22.954  65.217  1.00 60.97  ? 306  ALA D C   1 
ATOM   10149 O O   . ALA D 1 231 ? -52.271 22.947  65.303  1.00 64.60  ? 306  ALA D O   1 
ATOM   10150 C CB  . ALA D 1 231 ? -49.934 22.453  63.023  1.00 52.60  ? 306  ALA D CB  1 
ATOM   10151 N N   . ILE D 1 232 ? -50.247 22.439  66.164  1.00 55.25  ? 307  ILE D N   1 
ATOM   10152 C CA  . ILE D 1 232 ? -50.810 21.927  67.414  1.00 59.63  ? 307  ILE D CA  1 
ATOM   10153 C C   . ILE D 1 232 ? -51.662 23.000  68.083  1.00 56.75  ? 307  ILE D C   1 
ATOM   10154 O O   . ILE D 1 232 ? -52.826 22.769  68.453  1.00 61.12  ? 307  ILE D O   1 
ATOM   10155 C CB  . ILE D 1 232 ? -49.686 21.436  68.346  1.00 60.82  ? 307  ILE D CB  1 
ATOM   10156 C CG1 . ILE D 1 232 ? -48.987 20.215  67.742  1.00 54.96  ? 307  ILE D CG1 1 
ATOM   10157 C CG2 . ILE D 1 232 ? -50.238 21.111  69.726  1.00 66.74  ? 307  ILE D CG2 1 
ATOM   10158 C CD1 . ILE D 1 232 ? -47.846 19.681  68.582  1.00 53.01  ? 307  ILE D CD1 1 
ATOM   10159 N N   . CYS D 1 233 ? -51.095 24.202  68.225  1.00 51.88  ? 308  CYS D N   1 
ATOM   10160 C CA  . CYS D 1 233 ? -51.800 25.275  68.923  1.00 47.69  ? 308  CYS D CA  1 
ATOM   10161 C C   . CYS D 1 233 ? -53.080 25.676  68.191  1.00 55.03  ? 308  CYS D C   1 
ATOM   10162 O O   . CYS D 1 233 ? -54.128 25.884  68.816  1.00 65.51  ? 308  CYS D O   1 
ATOM   10163 C CB  . CYS D 1 233 ? -50.875 26.480  69.101  1.00 39.32  ? 308  CYS D CB  1 
ATOM   10164 S SG  . CYS D 1 233 ? -49.372 26.126  70.026  1.00 60.59  ? 308  CYS D SG  1 
ATOM   10165 N N   . ILE D 1 234 ? -53.010 25.796  66.862  1.00 49.12  ? 309  ILE D N   1 
ATOM   10166 C CA  . ILE D 1 234 ? -54.174 26.219  66.081  1.00 52.51  ? 309  ILE D CA  1 
ATOM   10167 C C   . ILE D 1 234 ? -55.299 25.198  66.211  1.00 55.18  ? 309  ILE D C   1 
ATOM   10168 O O   . ILE D 1 234 ? -56.470 25.548  66.429  1.00 61.53  ? 309  ILE D O   1 
ATOM   10169 C CB  . ILE D 1 234 ? -53.779 26.437  64.607  1.00 48.66  ? 309  ILE D CB  1 
ATOM   10170 C CG1 . ILE D 1 234 ? -52.880 27.666  64.462  1.00 48.08  ? 309  ILE D CG1 1 
ATOM   10171 C CG2 . ILE D 1 234 ? -55.017 26.576  63.734  1.00 42.00  ? 309  ILE D CG2 1 
ATOM   10172 C CD1 . ILE D 1 234 ? -53.422 28.905  65.128  1.00 56.43  ? 309  ILE D CD1 1 
ATOM   10173 N N   . GLU D 1 235 ? -54.959 23.914  66.070  1.00 50.86  ? 310  GLU D N   1 
ATOM   10174 C CA  . GLU D 1 235 ? -55.967 22.868  66.182  1.00 61.79  ? 310  GLU D CA  1 
ATOM   10175 C C   . GLU D 1 235 ? -56.630 22.895  67.553  1.00 61.35  ? 310  GLU D C   1 
ATOM   10176 O O   . GLU D 1 235 ? -57.862 22.787  67.666  1.00 66.18  ? 310  GLU D O   1 
ATOM   10177 C CB  . GLU D 1 235 ? -55.322 21.511  65.906  1.00 60.09  ? 310  GLU D CB  1 
ATOM   10178 C CG  . GLU D 1 235 ? -56.270 20.331  65.902  1.00 60.86  ? 310  GLU D CG  1 
ATOM   10179 C CD  . GLU D 1 235 ? -55.557 19.032  65.578  1.00 69.11  ? 310  GLU D CD  1 
ATOM   10180 O OE1 . GLU D 1 235 ? -54.721 18.592  66.395  1.00 70.84  ? 310  GLU D OE1 1 
ATOM   10181 O OE2 . GLU D 1 235 ? -55.818 18.466  64.497  1.00 87.22  ? 310  GLU D OE2 1 
ATOM   10182 N N   . GLU D 1 236 ? -55.838 23.076  68.613  1.00 53.73  ? 311  GLU D N   1 
ATOM   10183 C CA  . GLU D 1 236 ? -56.442 23.031  69.940  1.00 53.28  ? 311  GLU D CA  1 
ATOM   10184 C C   . GLU D 1 236 ? -57.257 24.285  70.254  1.00 66.86  ? 311  GLU D C   1 
ATOM   10185 O O   . GLU D 1 236 ? -58.258 24.196  70.977  1.00 69.99  ? 311  GLU D O   1 
ATOM   10186 C CB  . GLU D 1 236 ? -55.376 22.783  71.001  1.00 55.91  ? 311  GLU D CB  1 
ATOM   10187 C CG  . GLU D 1 236 ? -54.869 21.352  70.978  1.00 64.49  ? 311  GLU D CG  1 
ATOM   10188 C CD  . GLU D 1 236 ? -55.799 20.405  71.712  1.00 61.37  ? 311  GLU D CD  1 
ATOM   10189 O OE1 . GLU D 1 236 ? -56.245 20.754  72.827  1.00 59.26  ? 311  GLU D OE1 1 
ATOM   10190 O OE2 . GLU D 1 236 ? -56.078 19.309  71.180  1.00 60.70  ? 311  GLU D OE2 1 
ATOM   10191 N N   . ILE D 1 237 ? -56.881 25.450  69.718  1.00 63.83  ? 312  ILE D N   1 
ATOM   10192 C CA  . ILE D 1 237 ? -57.723 26.622  69.948  1.00 61.12  ? 312  ILE D CA  1 
ATOM   10193 C C   . ILE D 1 237 ? -59.048 26.470  69.207  1.00 57.69  ? 312  ILE D C   1 
ATOM   10194 O O   . ILE D 1 237 ? -60.108 26.864  69.716  1.00 57.34  ? 312  ILE D O   1 
ATOM   10195 C CB  . ILE D 1 237 ? -56.996 27.932  69.576  1.00 50.33  ? 312  ILE D CB  1 
ATOM   10196 C CG1 . ILE D 1 237 ? -57.793 29.134  70.088  1.00 53.10  ? 312  ILE D CG1 1 
ATOM   10197 C CG2 . ILE D 1 237 ? -56.796 28.066  68.082  1.00 47.57  ? 312  ILE D CG2 1 
ATOM   10198 C CD1 . ILE D 1 237 ? -57.188 30.479  69.749  1.00 43.16  ? 312  ILE D CD1 1 
ATOM   10199 N N   . GLY D 1 238 ? -59.019 25.864  68.015  1.00 53.04  ? 313  GLY D N   1 
ATOM   10200 C CA  . GLY D 1 238 ? -60.270 25.534  67.351  1.00 59.65  ? 313  GLY D CA  1 
ATOM   10201 C C   . GLY D 1 238 ? -61.133 24.596  68.176  1.00 57.32  ? 313  GLY D C   1 
ATOM   10202 O O   . GLY D 1 238 ? -62.354 24.772  68.268  1.00 55.44  ? 313  GLY D O   1 
ATOM   10203 N N   . ILE D 1 239 ? -60.508 23.590  68.793  1.00 53.23  ? 314  ILE D N   1 
ATOM   10204 C CA  . ILE D 1 239 ? -61.252 22.665  69.651  1.00 52.76  ? 314  ILE D CA  1 
ATOM   10205 C C   . ILE D 1 239 ? -61.905 23.416  70.809  1.00 55.29  ? 314  ILE D C   1 
ATOM   10206 O O   . ILE D 1 239 ? -63.077 23.188  71.137  1.00 56.11  ? 314  ILE D O   1 
ATOM   10207 C CB  . ILE D 1 239 ? -60.335 21.538  70.161  1.00 61.60  ? 314  ILE D CB  1 
ATOM   10208 C CG1 . ILE D 1 239 ? -60.042 20.538  69.041  1.00 54.42  ? 314  ILE D CG1 1 
ATOM   10209 C CG2 . ILE D 1 239 ? -60.964 20.830  71.353  1.00 52.21  ? 314  ILE D CG2 1 
ATOM   10210 C CD1 . ILE D 1 239 ? -58.698 19.848  69.177  1.00 59.80  ? 314  ILE D CD1 1 
ATOM   10211 N N   . TRP D 1 240 ? -61.148 24.309  71.456  1.00 59.49  ? 315  TRP D N   1 
ATOM   10212 C CA  . TRP D 1 240 ? -61.705 25.090  72.560  1.00 57.88  ? 315  TRP D CA  1 
ATOM   10213 C C   . TRP D 1 240 ? -62.899 25.916  72.104  1.00 53.24  ? 315  TRP D C   1 
ATOM   10214 O O   . TRP D 1 240 ? -63.918 25.989  72.800  1.00 44.94  ? 315  TRP D O   1 
ATOM   10215 C CB  . TRP D 1 240 ? -60.646 26.012  73.160  1.00 62.17  ? 315  TRP D CB  1 
ATOM   10216 C CG  . TRP D 1 240 ? -59.364 25.349  73.516  1.00 58.51  ? 315  TRP D CG  1 
ATOM   10217 C CD1 . TRP D 1 240 ? -59.171 24.037  73.835  1.00 60.72  ? 315  TRP D CD1 1 
ATOM   10218 C CD2 . TRP D 1 240 ? -58.078 25.970  73.571  1.00 52.68  ? 315  TRP D CD2 1 
ATOM   10219 N NE1 . TRP D 1 240 ? -57.842 23.806  74.096  1.00 60.25  ? 315  TRP D NE1 1 
ATOM   10220 C CE2 . TRP D 1 240 ? -57.151 24.978  73.939  1.00 58.31  ? 315  TRP D CE2 1 
ATOM   10221 C CE3 . TRP D 1 240 ? -57.622 27.273  73.350  1.00 56.48  ? 315  TRP D CE3 1 
ATOM   10222 C CZ2 . TRP D 1 240 ? -55.794 25.246  74.088  1.00 64.60  ? 315  TRP D CZ2 1 
ATOM   10223 C CZ3 . TRP D 1 240 ? -56.278 27.537  73.496  1.00 64.04  ? 315  TRP D CZ3 1 
ATOM   10224 C CH2 . TRP D 1 240 ? -55.379 26.530  73.863  1.00 69.16  ? 315  TRP D CH2 1 
ATOM   10225 N N   . MET D 1 241 ? -62.784 26.556  70.939  1.00 48.75  ? 316  MET D N   1 
ATOM   10226 C CA  . MET D 1 241 ? -63.893 27.354  70.430  1.00 37.40  ? 316  MET D CA  1 
ATOM   10227 C C   . MET D 1 241 ? -65.119 26.491  70.161  1.00 44.97  ? 316  MET D C   1 
ATOM   10228 O O   . MET D 1 241 ? -66.252 26.920  70.405  1.00 61.38  ? 316  MET D O   1 
ATOM   10229 C CB  . MET D 1 241 ? -63.467 28.096  69.168  1.00 61.30  ? 316  MET D CB  1 
ATOM   10230 C CG  . MET D 1 241 ? -62.295 29.028  69.389  1.00 60.08  ? 316  MET D CG  1 
ATOM   10231 S SD  . MET D 1 241 ? -62.222 30.317  68.139  1.00 60.31  ? 316  MET D SD  1 
ATOM   10232 C CE  . MET D 1 241 ? -60.786 29.779  67.223  1.00 53.19  ? 316  MET D CE  1 
ATOM   10233 N N   . LYS D 1 242 ? -64.913 25.266  69.671  1.00 47.72  ? 317  LYS D N   1 
ATOM   10234 C CA  . LYS D 1 242 ? -66.053 24.398  69.377  1.00 45.66  ? 317  LYS D CA  1 
ATOM   10235 C C   . LYS D 1 242 ? -66.734 23.908  70.653  1.00 46.76  ? 317  LYS D C   1 
ATOM   10236 O O   . LYS D 1 242 ? -67.965 23.952  70.764  1.00 54.43  ? 317  LYS D O   1 
ATOM   10237 C CB  . LYS D 1 242 ? -65.614 23.211  68.521  1.00 57.74  ? 317  LYS D CB  1 
ATOM   10238 C CG  . LYS D 1 242 ? -66.668 22.748  67.527  1.00 52.50  ? 317  LYS D CG  1 
ATOM   10239 C CD  . LYS D 1 242 ? -66.300 21.398  66.936  1.00 68.01  ? 317  LYS D CD  1 
ATOM   10240 C CE  . LYS D 1 242 ? -67.532 20.602  66.540  1.00 64.12  ? 317  LYS D CE  1 
ATOM   10241 N NZ  . LYS D 1 242 ? -67.195 19.178  66.260  1.00 63.31  ? 317  LYS D NZ  1 
ATOM   10242 N N   . MET D 1 243 ? -65.953 23.436  71.630  1.00 50.44  ? 318  MET D N   1 
ATOM   10243 C CA  . MET D 1 243 ? -66.553 22.765  72.783  1.00 51.22  ? 318  MET D CA  1 
ATOM   10244 C C   . MET D 1 243 ? -67.234 23.740  73.737  1.00 44.93  ? 318  MET D C   1 
ATOM   10245 O O   . MET D 1 243 ? -68.177 23.358  74.440  1.00 46.55  ? 318  MET D O   1 
ATOM   10246 C CB  . MET D 1 243 ? -65.501 21.958  73.543  1.00 55.56  ? 318  MET D CB  1 
ATOM   10247 C CG  . MET D 1 243 ? -64.336 22.785  74.048  1.00 51.12  ? 318  MET D CG  1 
ATOM   10248 S SD  . MET D 1 243 ? -62.947 21.764  74.560  1.00 65.10  ? 318  MET D SD  1 
ATOM   10249 C CE  . MET D 1 243 ? -63.721 20.775  75.837  1.00 43.33  ? 318  MET D CE  1 
ATOM   10250 N N   . TYR D 1 244 ? -66.768 24.996  73.789  1.00 44.63  ? 319  TYR D N   1 
ATOM   10251 C CA  . TYR D 1 244 ? -67.248 25.986  74.750  1.00 52.32  ? 319  TYR D CA  1 
ATOM   10252 C C   . TYR D 1 244 ? -67.475 27.298  73.990  1.00 52.78  ? 319  TYR D C   1 
ATOM   10253 O O   . TYR D 1 244 ? -66.778 28.291  74.187  1.00 58.13  ? 319  TYR D O   1 
ATOM   10254 C CB  . TYR D 1 244 ? -66.258 26.156  75.906  1.00 45.87  ? 319  TYR D CB  1 
ATOM   10255 C CG  . TYR D 1 244 ? -66.861 26.690  77.186  1.00 52.51  ? 319  TYR D CG  1 
ATOM   10256 C CD1 . TYR D 1 244 ? -68.187 27.092  77.239  1.00 40.01  ? 319  TYR D CD1 1 
ATOM   10257 C CD2 . TYR D 1 244 ? -66.100 26.787  78.346  1.00 62.42  ? 319  TYR D CD2 1 
ATOM   10258 C CE1 . TYR D 1 244 ? -68.738 27.579  78.406  1.00 36.85  ? 319  TYR D CE1 1 
ATOM   10259 C CE2 . TYR D 1 244 ? -66.645 27.273  79.521  1.00 55.10  ? 319  TYR D CE2 1 
ATOM   10260 C CZ  . TYR D 1 244 ? -67.964 27.668  79.543  1.00 39.32  ? 319  TYR D CZ  1 
ATOM   10261 O OH  . TYR D 1 244 ? -68.510 28.153  80.708  1.00 61.99  ? 319  TYR D OH  1 
ATOM   10262 N N   . SER D 1 245 ? -68.475 27.287  73.104  1.00 55.28  ? 320  SER D N   1 
ATOM   10263 C CA  . SER D 1 245 ? -68.688 28.413  72.200  1.00 55.35  ? 320  SER D CA  1 
ATOM   10264 C C   . SER D 1 245 ? -68.953 29.704  72.964  1.00 60.68  ? 320  SER D C   1 
ATOM   10265 O O   . SER D 1 245 ? -68.441 30.768  72.597  1.00 65.99  ? 320  SER D O   1 
ATOM   10266 C CB  . SER D 1 245 ? -69.847 28.108  71.252  1.00 61.72  ? 320  SER D CB  1 
ATOM   10267 O OG  . SER D 1 245 ? -69.641 26.881  70.576  1.00 81.49  ? 320  SER D OG  1 
ATOM   10268 N N   . ASP D 1 246 ? -69.738 29.628  74.040  1.00 64.31  ? 321  ASP D N   1 
ATOM   10269 C CA  . ASP D 1 246 ? -70.111 30.839  74.762  1.00 67.03  ? 321  ASP D CA  1 
ATOM   10270 C C   . ASP D 1 246 ? -68.908 31.518  75.402  1.00 59.76  ? 321  ASP D C   1 
ATOM   10271 O O   . ASP D 1 246 ? -68.912 32.741  75.580  1.00 67.55  ? 321  ASP D O   1 
ATOM   10272 C CB  . ASP D 1 246 ? -71.162 30.514  75.822  1.00 62.92  ? 321  ASP D CB  1 
ATOM   10273 C CG  . ASP D 1 246 ? -72.543 30.331  75.232  1.00 84.77  ? 321  ASP D CG  1 
ATOM   10274 O OD1 . ASP D 1 246 ? -72.643 30.187  73.994  1.00 94.63  ? 321  ASP D OD1 1 
ATOM   10275 O OD2 . ASP D 1 246 ? -73.526 30.335  76.001  1.00 73.48  ? 321  ASP D OD2 1 
ATOM   10276 N N   . ALA D 1 247 ? -67.870 30.753  75.743  1.00 53.54  ? 322  ALA D N   1 
ATOM   10277 C CA  . ALA D 1 247 ? -66.714 31.299  76.439  1.00 62.99  ? 322  ALA D CA  1 
ATOM   10278 C C   . ALA D 1 247 ? -65.474 31.450  75.571  1.00 66.01  ? 322  ALA D C   1 
ATOM   10279 O O   . ALA D 1 247 ? -64.611 32.268  75.904  1.00 77.31  ? 322  ALA D O   1 
ATOM   10280 C CB  . ALA D 1 247 ? -66.359 30.424  77.651  1.00 49.52  ? 322  ALA D CB  1 
ATOM   10281 N N   . PHE D 1 248 ? -65.354 30.694  74.477  1.00 62.19  ? 323  PHE D N   1 
ATOM   10282 C CA  . PHE D 1 248 ? -64.146 30.720  73.665  1.00 46.20  ? 323  PHE D CA  1 
ATOM   10283 C C   . PHE D 1 248 ? -64.369 31.106  72.209  1.00 47.09  ? 323  PHE D C   1 
ATOM   10284 O O   . PHE D 1 248 ? -63.385 31.350  71.502  1.00 64.74  ? 323  PHE D O   1 
ATOM   10285 C CB  . PHE D 1 248 ? -63.435 29.360  73.719  1.00 42.99  ? 323  PHE D CB  1 
ATOM   10286 C CG  . PHE D 1 248 ? -62.671 29.134  74.990  1.00 51.40  ? 323  PHE D CG  1 
ATOM   10287 C CD1 . PHE D 1 248 ? -63.314 28.678  76.132  1.00 58.75  ? 323  PHE D CD1 1 
ATOM   10288 C CD2 . PHE D 1 248 ? -61.314 29.399  75.051  1.00 41.36  ? 323  PHE D CD2 1 
ATOM   10289 C CE1 . PHE D 1 248 ? -62.610 28.476  77.307  1.00 50.60  ? 323  PHE D CE1 1 
ATOM   10290 C CE2 . PHE D 1 248 ? -60.607 29.202  76.220  1.00 42.70  ? 323  PHE D CE2 1 
ATOM   10291 C CZ  . PHE D 1 248 ? -61.255 28.739  77.351  1.00 40.43  ? 323  PHE D CZ  1 
ATOM   10292 N N   . LEU D 1 249 ? -65.615 31.170  71.738  1.00 52.73  ? 324  LEU D N   1 
ATOM   10293 C CA  . LEU D 1 249 ? -65.897 31.675  70.394  1.00 54.69  ? 324  LEU D CA  1 
ATOM   10294 C C   . LEU D 1 249 ? -66.046 33.191  70.484  1.00 58.71  ? 324  LEU D C   1 
ATOM   10295 O O   . LEU D 1 249 ? -67.144 33.744  70.575  1.00 68.55  ? 324  LEU D O   1 
ATOM   10296 C CB  . LEU D 1 249 ? -67.137 31.011  69.808  1.00 54.37  ? 324  LEU D CB  1 
ATOM   10297 C CG  . LEU D 1 249 ? -67.448 31.325  68.343  1.00 46.75  ? 324  LEU D CG  1 
ATOM   10298 C CD1 . LEU D 1 249 ? -66.212 31.146  67.474  1.00 57.22  ? 324  LEU D CD1 1 
ATOM   10299 C CD2 . LEU D 1 249 ? -68.596 30.465  67.838  1.00 42.56  ? 324  LEU D CD2 1 
ATOM   10300 N N   . ASN D 1 250 ? -64.900 33.868  70.477  1.00 71.80  ? 325  ASN D N   1 
ATOM   10301 C CA  . ASN D 1 250 ? -64.845 35.319  70.527  1.00 68.10  ? 325  ASN D CA  1 
ATOM   10302 C C   . ASN D 1 250 ? -63.807 35.803  69.528  1.00 73.99  ? 325  ASN D C   1 
ATOM   10303 O O   . ASN D 1 250 ? -62.989 35.026  69.027  1.00 80.91  ? 325  ASN D O   1 
ATOM   10304 C CB  . ASN D 1 250 ? -64.499 35.833  71.933  1.00 56.19  ? 325  ASN D CB  1 
ATOM   10305 C CG  . ASN D 1 250 ? -65.161 35.023  73.030  1.00 91.06  ? 325  ASN D CG  1 
ATOM   10306 O OD1 . ASN D 1 250 ? -66.383 35.037  73.180  1.00 107.84 ? 325  ASN D OD1 1 
ATOM   10307 N ND2 . ASN D 1 250 ? -64.352 34.315  73.809  1.00 87.09  ? 325  ASN D ND2 1 
ATOM   10308 N N   . ASP D 1 251 ? -63.852 37.104  69.237  1.00 73.43  ? 326  ASP D N   1 
ATOM   10309 C CA  . ASP D 1 251 ? -62.835 37.697  68.376  1.00 66.55  ? 326  ASP D CA  1 
ATOM   10310 C C   . ASP D 1 251 ? -61.448 37.567  68.990  1.00 59.90  ? 326  ASP D C   1 
ATOM   10311 O O   . ASP D 1 251 ? -60.462 37.383  68.264  1.00 63.77  ? 326  ASP D O   1 
ATOM   10312 C CB  . ASP D 1 251 ? -63.167 39.166  68.103  1.00 77.03  ? 326  ASP D CB  1 
ATOM   10313 C CG  . ASP D 1 251 ? -64.602 39.369  67.647  1.00 89.73  ? 326  ASP D CG  1 
ATOM   10314 O OD1 . ASP D 1 251 ? -65.049 38.639  66.737  1.00 79.37  ? 326  ASP D OD1 1 
ATOM   10315 O OD2 . ASP D 1 251 ? -65.282 40.264  68.192  1.00 95.04  ? 326  ASP D OD2 1 
ATOM   10316 N N   . SER D 1 252 ? -61.359 37.635  70.323  1.00 65.82  ? 327  SER D N   1 
ATOM   10317 C CA  . SER D 1 252 ? -60.073 37.527  71.005  1.00 66.51  ? 327  SER D CA  1 
ATOM   10318 C C   . SER D 1 252 ? -59.390 36.196  70.722  1.00 69.57  ? 327  SER D C   1 
ATOM   10319 O O   . SER D 1 252 ? -58.157 36.114  70.754  1.00 75.09  ? 327  SER D O   1 
ATOM   10320 C CB  . SER D 1 252 ? -60.264 37.708  72.510  1.00 64.93  ? 327  SER D CB  1 
ATOM   10321 O OG  . SER D 1 252 ? -61.161 36.737  73.022  1.00 80.24  ? 327  SER D OG  1 
ATOM   10322 N N   . TYR D 1 253 ? -60.166 35.146  70.454  1.00 65.27  ? 328  TYR D N   1 
ATOM   10323 C CA  . TYR D 1 253 ? -59.619 33.845  70.094  1.00 69.07  ? 328  TYR D CA  1 
ATOM   10324 C C   . TYR D 1 253 ? -59.606 33.613  68.589  1.00 70.23  ? 328  TYR D C   1 
ATOM   10325 O O   . TYR D 1 253 ? -58.677 32.985  68.071  1.00 68.81  ? 328  TYR D O   1 
ATOM   10326 C CB  . TYR D 1 253 ? -60.415 32.729  70.778  1.00 56.98  ? 328  TYR D CB  1 
ATOM   10327 C CG  . TYR D 1 253 ? -60.255 32.719  72.280  1.00 56.63  ? 328  TYR D CG  1 
ATOM   10328 C CD1 . TYR D 1 253 ? -59.053 32.343  72.867  1.00 68.15  ? 328  TYR D CD1 1 
ATOM   10329 C CD2 . TYR D 1 253 ? -61.303 33.085  73.110  1.00 50.97  ? 328  TYR D CD2 1 
ATOM   10330 C CE1 . TYR D 1 253 ? -58.903 32.336  74.241  1.00 60.38  ? 328  TYR D CE1 1 
ATOM   10331 C CE2 . TYR D 1 253 ? -61.163 33.079  74.482  1.00 52.16  ? 328  TYR D CE2 1 
ATOM   10332 C CZ  . TYR D 1 253 ? -59.961 32.704  75.043  1.00 50.26  ? 328  TYR D CZ  1 
ATOM   10333 O OH  . TYR D 1 253 ? -59.818 32.698  76.411  1.00 72.66  ? 328  TYR D OH  1 
ATOM   10334 N N   . LEU D 1 254 ? -60.613 34.125  67.876  1.00 52.52  ? 329  LEU D N   1 
ATOM   10335 C CA  . LEU D 1 254 ? -60.683 33.949  66.429  1.00 57.39  ? 329  LEU D CA  1 
ATOM   10336 C C   . LEU D 1 254 ? -59.551 34.671  65.710  1.00 61.10  ? 329  LEU D C   1 
ATOM   10337 O O   . LEU D 1 254 ? -59.181 34.278  64.594  1.00 64.30  ? 329  LEU D O   1 
ATOM   10338 C CB  . LEU D 1 254 ? -62.032 34.448  65.909  1.00 54.78  ? 329  LEU D CB  1 
ATOM   10339 C CG  . LEU D 1 254 ? -63.225 33.502  66.030  1.00 56.15  ? 329  LEU D CG  1 
ATOM   10340 C CD1 . LEU D 1 254 ? -64.528 34.287  65.997  1.00 66.30  ? 329  LEU D CD1 1 
ATOM   10341 C CD2 . LEU D 1 254 ? -63.191 32.461  64.925  1.00 53.92  ? 329  LEU D CD2 1 
ATOM   10342 N N   . LYS D 1 255 ? -59.006 35.733  66.315  1.00 57.21  ? 330  LYS D N   1 
ATOM   10343 C CA  . LYS D 1 255 ? -57.966 36.503  65.641  1.00 50.13  ? 330  LYS D CA  1 
ATOM   10344 C C   . LYS D 1 255 ? -56.737 35.655  65.360  1.00 50.87  ? 330  LYS D C   1 
ATOM   10345 O O   . LYS D 1 255 ? -56.057 35.869  64.354  1.00 57.11  ? 330  LYS D O   1 
ATOM   10346 C CB  . LYS D 1 255 ? -57.568 37.728  66.468  1.00 52.13  ? 330  LYS D CB  1 
ATOM   10347 C CG  . LYS D 1 255 ? -57.104 37.425  67.884  1.00 57.14  ? 330  LYS D CG  1 
ATOM   10348 C CD  . LYS D 1 255 ? -57.210 38.656  68.767  1.00 56.89  ? 330  LYS D CD  1 
ATOM   10349 C CE  . LYS D 1 255 ? -56.098 38.679  69.802  1.00 65.95  ? 330  LYS D CE  1 
ATOM   10350 N NZ  . LYS D 1 255 ? -56.235 39.824  70.743  1.00 87.02  ? 330  LYS D NZ  1 
ATOM   10351 N N   . TYR D 1 256 ? -56.437 34.689  66.228  1.00 54.43  ? 331  TYR D N   1 
ATOM   10352 C CA  . TYR D 1 256 ? -55.244 33.874  66.030  1.00 57.86  ? 331  TYR D CA  1 
ATOM   10353 C C   . TYR D 1 256 ? -55.400 32.961  64.823  1.00 54.84  ? 331  TYR D C   1 
ATOM   10354 O O   . TYR D 1 256 ? -54.477 32.835  64.009  1.00 62.71  ? 331  TYR D O   1 
ATOM   10355 C CB  . TYR D 1 256 ? -54.951 33.075  67.297  1.00 52.80  ? 331  TYR D CB  1 
ATOM   10356 C CG  . TYR D 1 256 ? -54.571 33.960  68.458  1.00 59.28  ? 331  TYR D CG  1 
ATOM   10357 C CD1 . TYR D 1 256 ? -53.295 34.500  68.557  1.00 65.96  ? 331  TYR D CD1 1 
ATOM   10358 C CD2 . TYR D 1 256 ? -55.500 34.291  69.433  1.00 56.69  ? 331  TYR D CD2 1 
ATOM   10359 C CE1 . TYR D 1 256 ? -52.948 35.323  69.611  1.00 59.67  ? 331  TYR D CE1 1 
ATOM   10360 C CE2 . TYR D 1 256 ? -55.164 35.113  70.488  1.00 63.40  ? 331  TYR D CE2 1 
ATOM   10361 C CZ  . TYR D 1 256 ? -53.889 35.626  70.573  1.00 56.03  ? 331  TYR D CZ  1 
ATOM   10362 O OH  . TYR D 1 256 ? -53.561 36.445  71.628  1.00 57.65  ? 331  TYR D OH  1 
ATOM   10363 N N   . VAL D 1 257 ? -56.568 32.331  64.683  1.00 50.58  ? 332  VAL D N   1 
ATOM   10364 C CA  . VAL D 1 257 ? -56.845 31.532  63.493  1.00 47.69  ? 332  VAL D CA  1 
ATOM   10365 C C   . VAL D 1 257 ? -56.812 32.404  62.247  1.00 51.98  ? 332  VAL D C   1 
ATOM   10366 O O   . VAL D 1 257 ? -56.221 32.031  61.226  1.00 58.72  ? 332  VAL D O   1 
ATOM   10367 C CB  . VAL D 1 257 ? -58.194 30.804  63.642  1.00 52.88  ? 332  VAL D CB  1 
ATOM   10368 C CG1 . VAL D 1 257 ? -58.563 30.085  62.355  1.00 49.38  ? 332  VAL D CG1 1 
ATOM   10369 C CG2 . VAL D 1 257 ? -58.130 29.824  64.804  1.00 38.89  ? 332  VAL D CG2 1 
ATOM   10370 N N   . GLY D 1 258 ? -57.434 33.584  62.313  1.00 51.68  ? 333  GLY D N   1 
ATOM   10371 C CA  . GLY D 1 258 ? -57.447 34.463  61.152  1.00 55.22  ? 333  GLY D CA  1 
ATOM   10372 C C   . GLY D 1 258 ? -56.059 34.908  60.732  1.00 62.50  ? 333  GLY D C   1 
ATOM   10373 O O   . GLY D 1 258 ? -55.747 34.963  59.539  1.00 68.12  ? 333  GLY D O   1 
ATOM   10374 N N   . TRP D 1 259 ? -55.210 35.239  61.705  1.00 53.38  ? 334  TRP D N   1 
ATOM   10375 C CA  . TRP D 1 259 ? -53.839 35.634  61.408  1.00 54.49  ? 334  TRP D CA  1 
ATOM   10376 C C   . TRP D 1 259 ? -53.064 34.471  60.814  1.00 56.21  ? 334  TRP D C   1 
ATOM   10377 O O   . TRP D 1 259 ? -52.417 34.602  59.767  1.00 64.12  ? 334  TRP D O   1 
ATOM   10378 C CB  . TRP D 1 259 ? -53.157 36.120  62.686  1.00 43.20  ? 334  TRP D CB  1 
ATOM   10379 C CG  . TRP D 1 259 ? -53.757 37.360  63.251  1.00 54.10  ? 334  TRP D CG  1 
ATOM   10380 C CD1 . TRP D 1 259 ? -54.564 38.249  62.607  1.00 60.62  ? 334  TRP D CD1 1 
ATOM   10381 C CD2 . TRP D 1 259 ? -53.640 37.827  64.599  1.00 48.46  ? 334  TRP D CD2 1 
ATOM   10382 N NE1 . TRP D 1 259 ? -54.930 39.260  63.462  1.00 65.07  ? 334  TRP D NE1 1 
ATOM   10383 C CE2 . TRP D 1 259 ? -54.379 39.022  64.693  1.00 52.83  ? 334  TRP D CE2 1 
ATOM   10384 C CE3 . TRP D 1 259 ? -52.970 37.357  65.733  1.00 50.95  ? 334  TRP D CE3 1 
ATOM   10385 C CZ2 . TRP D 1 259 ? -54.469 39.752  65.876  1.00 62.05  ? 334  TRP D CZ2 1 
ATOM   10386 C CZ3 . TRP D 1 259 ? -53.059 38.083  66.905  1.00 59.54  ? 334  TRP D CZ3 1 
ATOM   10387 C CH2 . TRP D 1 259 ? -53.803 39.268  66.967  1.00 66.28  ? 334  TRP D CH2 1 
ATOM   10388 N N   . THR D 1 260 ? -53.144 33.310  61.461  1.00 47.42  ? 335  THR D N   1 
ATOM   10389 C CA  . THR D 1 260 ? -52.332 32.176  61.074  1.00 46.84  ? 335  THR D CA  1 
ATOM   10390 C C   . THR D 1 260 ? -52.846 31.545  59.784  1.00 48.53  ? 335  THR D C   1 
ATOM   10391 O O   . THR D 1 260 ? -52.167 30.690  59.209  1.00 62.95  ? 335  THR D O   1 
ATOM   10392 C CB  . THR D 1 260 ? -52.319 31.200  62.249  1.00 44.50  ? 335  THR D CB  1 
ATOM   10393 O OG1 . THR D 1 260 ? -52.043 31.947  63.438  1.00 48.11  ? 335  THR D OG1 1 
ATOM   10394 C CG2 . THR D 1 260 ? -51.166 30.246  62.113  1.00 52.83  ? 335  THR D CG2 1 
ATOM   10395 N N   . MET D 1 261 ? -54.021 31.975  59.304  1.00 48.49  ? 336  MET D N   1 
ATOM   10396 C CA  . MET D 1 261 ? -54.469 31.633  57.955  1.00 63.42  ? 336  MET D CA  1 
ATOM   10397 C C   . MET D 1 261 ? -53.491 32.100  56.882  1.00 67.38  ? 336  MET D C   1 
ATOM   10398 O O   . MET D 1 261 ? -53.535 31.596  55.753  1.00 67.03  ? 336  MET D O   1 
ATOM   10399 C CB  . MET D 1 261 ? -55.845 32.251  57.699  1.00 62.08  ? 336  MET D CB  1 
ATOM   10400 C CG  . MET D 1 261 ? -57.001 31.455  58.271  1.00 50.57  ? 336  MET D CG  1 
ATOM   10401 S SD  . MET D 1 261 ? -58.541 31.936  57.492  1.00 78.73  ? 336  MET D SD  1 
ATOM   10402 C CE  . MET D 1 261 ? -58.380 33.711  57.615  1.00 62.07  ? 336  MET D CE  1 
ATOM   10403 N N   . HIS D 1 262 ? -52.613 33.046  57.207  1.00 62.11  ? 337  HIS D N   1 
ATOM   10404 C CA  . HIS D 1 262 ? -51.641 33.581  56.266  1.00 65.51  ? 337  HIS D CA  1 
ATOM   10405 C C   . HIS D 1 262 ? -50.277 32.915  56.393  1.00 68.95  ? 337  HIS D C   1 
ATOM   10406 O O   . HIS D 1 262 ? -49.312 33.383  55.780  1.00 70.07  ? 337  HIS D O   1 
ATOM   10407 C CB  . HIS D 1 262 ? -51.498 35.092  56.460  1.00 60.94  ? 337  HIS D CB  1 
ATOM   10408 C CG  . HIS D 1 262 ? -52.788 35.843  56.343  1.00 59.63  ? 337  HIS D CG  1 
ATOM   10409 N ND1 . HIS D 1 262 ? -53.789 35.753  57.287  1.00 66.54  ? 337  HIS D ND1 1 
ATOM   10410 C CD2 . HIS D 1 262 ? -53.239 36.700  55.396  1.00 66.07  ? 337  HIS D CD2 1 
ATOM   10411 C CE1 . HIS D 1 262 ? -54.803 36.520  56.924  1.00 71.90  ? 337  HIS D CE1 1 
ATOM   10412 N NE2 . HIS D 1 262 ? -54.494 37.105  55.781  1.00 70.59  ? 337  HIS D NE2 1 
ATOM   10413 N N   . ASP D 1 263 ? -50.177 31.842  57.177  1.00 68.39  ? 338  ASP D N   1 
ATOM   10414 C CA  . ASP D 1 263 ? -48.898 31.176  57.376  1.00 65.06  ? 338  ASP D CA  1 
ATOM   10415 C C   . ASP D 1 263 ? -48.381 30.600  56.065  1.00 65.71  ? 338  ASP D C   1 
ATOM   10416 O O   . ASP D 1 263 ? -49.145 30.068  55.255  1.00 63.06  ? 338  ASP D O   1 
ATOM   10417 C CB  . ASP D 1 263 ? -49.033 30.070  58.423  1.00 56.78  ? 338  ASP D CB  1 
ATOM   10418 C CG  . ASP D 1 263 ? -47.702 29.680  59.028  1.00 60.30  ? 338  ASP D CG  1 
ATOM   10419 O OD1 . ASP D 1 263 ? -46.901 29.024  58.331  1.00 69.24  ? 338  ASP D OD1 1 
ATOM   10420 O OD2 . ASP D 1 263 ? -47.455 30.040  60.196  1.00 63.89  ? 338  ASP D OD2 1 
ATOM   10421 N N   . LYS D 1 264 ? -47.066 30.712  55.860  1.00 61.52  ? 339  LYS D N   1 
ATOM   10422 C CA  . LYS D 1 264 ? -46.466 30.222  54.623  1.00 61.84  ? 339  LYS D CA  1 
ATOM   10423 C C   . LYS D 1 264 ? -46.599 28.708  54.507  1.00 67.67  ? 339  LYS D C   1 
ATOM   10424 O O   . LYS D 1 264 ? -46.798 28.175  53.409  1.00 77.41  ? 339  LYS D O   1 
ATOM   10425 C CB  . LYS D 1 264 ? -44.997 30.641  54.547  1.00 61.66  ? 339  LYS D CB  1 
ATOM   10426 C CG  . LYS D 1 264 ? -44.748 32.139  54.722  1.00 58.87  ? 339  LYS D CG  1 
ATOM   10427 C CD  . LYS D 1 264 ? -45.172 32.941  53.495  1.00 44.71  ? 339  LYS D CD  1 
ATOM   10428 C CE  . LYS D 1 264 ? -46.439 33.735  53.767  1.00 67.19  ? 339  LYS D CE  1 
ATOM   10429 N NZ  . LYS D 1 264 ? -46.374 35.091  53.162  1.00 74.09  ? 339  LYS D NZ  1 
ATOM   10430 N N   . GLN D 1 265 ? -46.493 28.000  55.628  1.00 72.41  ? 340  GLN D N   1 
ATOM   10431 C CA  . GLN D 1 265 ? -46.608 26.548  55.616  1.00 71.19  ? 340  GLN D CA  1 
ATOM   10432 C C   . GLN D 1 265 ? -48.054 26.125  55.383  1.00 69.50  ? 340  GLN D C   1 
ATOM   10433 O O   . GLN D 1 265 ? -48.984 26.697  55.956  1.00 82.11  ? 340  GLN D O   1 
ATOM   10434 C CB  . GLN D 1 265 ? -46.091 25.972  56.933  1.00 70.13  ? 340  GLN D CB  1 
ATOM   10435 C CG  . GLN D 1 265 ? -44.578 25.878  57.006  1.00 82.77  ? 340  GLN D CG  1 
ATOM   10436 C CD  . GLN D 1 265 ? -44.008 24.965  55.939  1.00 97.80  ? 340  GLN D CD  1 
ATOM   10437 O OE1 . GLN D 1 265 ? -43.297 25.413  55.039  1.00 81.51  ? 340  GLN D OE1 1 
ATOM   10438 N NE2 . GLN D 1 265 ? -44.315 23.674  56.036  1.00 106.07 ? 340  GLN D NE2 1 
ATOM   10439 N N   . GLY D 1 266 ? -48.239 25.110  54.535  1.00 69.22  ? 341  GLY D N   1 
ATOM   10440 C CA  . GLY D 1 266 ? -49.583 24.692  54.175  1.00 67.48  ? 341  GLY D CA  1 
ATOM   10441 C C   . GLY D 1 266 ? -50.290 23.903  55.259  1.00 62.23  ? 341  GLY D C   1 
ATOM   10442 O O   . GLY D 1 266 ? -51.520 23.965  55.375  1.00 61.40  ? 341  GLY D O   1 
ATOM   10443 N N   . GLU D 1 267 ? -49.534 23.139  56.051  1.00 66.14  ? 342  GLU D N   1 
ATOM   10444 C CA  . GLU D 1 267 ? -50.122 22.371  57.143  1.00 68.00  ? 342  GLU D CA  1 
ATOM   10445 C C   . GLU D 1 267 ? -50.836 23.284  58.131  1.00 65.62  ? 342  GLU D C   1 
ATOM   10446 O O   . GLU D 1 267 ? -51.962 23.001  58.566  1.00 67.57  ? 342  GLU D O   1 
ATOM   10447 C CB  . GLU D 1 267 ? -49.026 21.565  57.839  1.00 62.67  ? 342  GLU D CB  1 
ATOM   10448 C CG  . GLU D 1 267 ? -47.665 22.265  57.833  1.00 79.36  ? 342  GLU D CG  1 
ATOM   10449 C CD  . GLU D 1 267 ? -46.631 21.545  58.675  1.00 89.38  ? 342  GLU D CD  1 
ATOM   10450 O OE1 . GLU D 1 267 ? -46.992 21.036  59.757  1.00 77.73  ? 342  GLU D OE1 1 
ATOM   10451 O OE2 . GLU D 1 267 ? -45.459 21.475  58.244  1.00 95.28  ? 342  GLU D OE2 1 
ATOM   10452 N N   . VAL D 1 268 ? -50.202 24.405  58.470  1.00 54.40  ? 343  VAL D N   1 
ATOM   10453 C CA  . VAL D 1 268 ? -50.780 25.337  59.430  1.00 63.49  ? 343  VAL D CA  1 
ATOM   10454 C C   . VAL D 1 268 ? -52.043 25.976  58.861  1.00 60.52  ? 343  VAL D C   1 
ATOM   10455 O O   . VAL D 1 268 ? -53.059 26.121  59.560  1.00 62.81  ? 343  VAL D O   1 
ATOM   10456 C CB  . VAL D 1 268 ? -49.722 26.382  59.828  1.00 52.59  ? 343  VAL D CB  1 
ATOM   10457 C CG1 . VAL D 1 268 ? -50.315 27.390  60.751  1.00 48.81  ? 343  VAL D CG1 1 
ATOM   10458 C CG2 . VAL D 1 268 ? -48.526 25.686  60.486  1.00 54.04  ? 343  VAL D CG2 1 
ATOM   10459 N N   . ARG D 1 269 ? -52.002 26.355  57.580  1.00 55.83  ? 344  ARG D N   1 
ATOM   10460 C CA  . ARG D 1 269 ? -53.166 26.932  56.917  1.00 55.71  ? 344  ARG D CA  1 
ATOM   10461 C C   . ARG D 1 269 ? -54.340 25.959  56.933  1.00 62.97  ? 344  ARG D C   1 
ATOM   10462 O O   . ARG D 1 269 ? -55.485 26.343  57.218  1.00 63.19  ? 344  ARG D O   1 
ATOM   10463 C CB  . ARG D 1 269 ? -52.795 27.305  55.480  1.00 52.50  ? 344  ARG D CB  1 
ATOM   10464 C CG  . ARG D 1 269 ? -52.128 28.664  55.336  1.00 59.44  ? 344  ARG D CG  1 
ATOM   10465 C CD  . ARG D 1 269 ? -52.048 29.110  53.881  1.00 66.72  ? 344  ARG D CD  1 
ATOM   10466 N NE  . ARG D 1 269 ? -51.650 28.037  52.976  1.00 61.57  ? 344  ARG D NE  1 
ATOM   10467 C CZ  . ARG D 1 269 ? -50.408 27.820  52.566  1.00 61.87  ? 344  ARG D CZ  1 
ATOM   10468 N NH1 . ARG D 1 269 ? -49.400 28.567  52.986  1.00 60.05  ? 344  ARG D NH1 1 
ATOM   10469 N NH2 . ARG D 1 269 ? -50.170 26.829  51.711  1.00 66.30  ? 344  ARG D NH2 1 
ATOM   10470 N N   . LEU D 1 270 ? -54.069 24.688  56.620  1.00 59.37  ? 345  LEU D N   1 
ATOM   10471 C CA  . LEU D 1 270 ? -55.112 23.668  56.662  1.00 57.17  ? 345  LEU D CA  1 
ATOM   10472 C C   . LEU D 1 270 ? -55.678 23.508  58.067  1.00 60.15  ? 345  LEU D C   1 
ATOM   10473 O O   . LEU D 1 270 ? -56.885 23.286  58.236  1.00 62.92  ? 345  LEU D O   1 
ATOM   10474 C CB  . LEU D 1 270 ? -54.565 22.332  56.164  1.00 51.07  ? 345  LEU D CB  1 
ATOM   10475 C CG  . LEU D 1 270 ? -55.629 21.242  56.047  1.00 53.91  ? 345  LEU D CG  1 
ATOM   10476 C CD1 . LEU D 1 270 ? -55.991 21.008  54.588  1.00 54.95  ? 345  LEU D CD1 1 
ATOM   10477 C CD2 . LEU D 1 270 ? -55.167 19.955  56.717  1.00 71.83  ? 345  LEU D CD2 1 
ATOM   10478 N N   . LYS D 1 271 ? -54.819 23.587  59.088  1.00 55.00  ? 346  LYS D N   1 
ATOM   10479 C CA  . LYS D 1 271 ? -55.316 23.484  60.457  1.00 56.51  ? 346  LYS D CA  1 
ATOM   10480 C C   . LYS D 1 271 ? -56.291 24.614  60.761  1.00 55.59  ? 346  LYS D C   1 
ATOM   10481 O O   . LYS D 1 271 ? -57.362 24.389  61.347  1.00 59.46  ? 346  LYS D O   1 
ATOM   10482 C CB  . LYS D 1 271 ? -54.151 23.502  61.447  1.00 47.23  ? 346  LYS D CB  1 
ATOM   10483 C CG  . LYS D 1 271 ? -53.367 22.206  61.485  1.00 52.00  ? 346  LYS D CG  1 
ATOM   10484 C CD  . LYS D 1 271 ? -54.276 20.995  61.578  1.00 68.41  ? 346  LYS D CD  1 
ATOM   10485 C CE  . LYS D 1 271 ? -53.464 19.708  61.620  1.00 68.81  ? 346  LYS D CE  1 
ATOM   10486 N NZ  . LYS D 1 271 ? -53.364 19.125  62.985  1.00 63.89  ? 346  LYS D NZ  1 
ATOM   10487 N N   . CYS D 1 272 ? -55.934 25.836  60.355  1.00 56.77  ? 347  CYS D N   1 
ATOM   10488 C CA  . CYS D 1 272 ? -56.846 26.967  60.518  1.00 43.74  ? 347  CYS D CA  1 
ATOM   10489 C C   . CYS D 1 272 ? -58.176 26.712  59.812  1.00 53.87  ? 347  CYS D C   1 
ATOM   10490 O O   . CYS D 1 272 ? -59.250 26.940  60.386  1.00 62.57  ? 347  CYS D O   1 
ATOM   10491 C CB  . CYS D 1 272 ? -56.202 28.255  59.996  1.00 41.54  ? 347  CYS D CB  1 
ATOM   10492 S SG  . CYS D 1 272 ? -54.603 28.695  60.716  1.00 72.26  ? 347  CYS D SG  1 
ATOM   10493 N N   . LEU D 1 273 ? -58.122 26.238  58.563  1.00 49.14  ? 348  LEU D N   1 
ATOM   10494 C CA  . LEU D 1 273 ? -59.354 26.023  57.800  1.00 50.51  ? 348  LEU D CA  1 
ATOM   10495 C C   . LEU D 1 273 ? -60.248 24.967  58.437  1.00 50.58  ? 348  LEU D C   1 
ATOM   10496 O O   . LEU D 1 273 ? -61.474 25.129  58.479  1.00 56.80  ? 348  LEU D O   1 
ATOM   10497 C CB  . LEU D 1 273 ? -59.039 25.650  56.353  1.00 61.59  ? 348  LEU D CB  1 
ATOM   10498 C CG  . LEU D 1 273 ? -58.533 26.810  55.506  1.00 58.28  ? 348  LEU D CG  1 
ATOM   10499 C CD1 . LEU D 1 273 ? -58.416 26.407  54.051  1.00 49.59  ? 348  LEU D CD1 1 
ATOM   10500 C CD2 . LEU D 1 273 ? -59.538 27.934  55.657  1.00 60.33  ? 348  LEU D CD2 1 
ATOM   10501 N N   . THR D 1 274 ? -59.664 23.871  58.918  1.00 47.39  ? 349  THR D N   1 
ATOM   10502 C CA  . THR D 1 274 ? -60.477 22.840  59.556  1.00 54.21  ? 349  THR D CA  1 
ATOM   10503 C C   . THR D 1 274 ? -61.106 23.352  60.847  1.00 61.11  ? 349  THR D C   1 
ATOM   10504 O O   . THR D 1 274 ? -62.295 23.104  61.111  1.00 62.35  ? 349  THR D O   1 
ATOM   10505 C CB  . THR D 1 274 ? -59.631 21.596  59.817  1.00 45.63  ? 349  THR D CB  1 
ATOM   10506 O OG1 . THR D 1 274 ? -58.444 21.972  60.524  1.00 69.75  ? 349  THR D OG1 1 
ATOM   10507 C CG2 . THR D 1 274 ? -59.236 20.944  58.497  1.00 50.03  ? 349  THR D CG2 1 
ATOM   10508 N N   . ALA D 1 275 ? -60.324 24.072  61.663  1.00 53.03  ? 350  ALA D N   1 
ATOM   10509 C CA  . ALA D 1 275 ? -60.886 24.683  62.863  1.00 53.46  ? 350  ALA D CA  1 
ATOM   10510 C C   . ALA D 1 275 ? -62.066 25.584  62.519  1.00 56.52  ? 350  ALA D C   1 
ATOM   10511 O O   . ALA D 1 275 ? -63.097 25.552  63.200  1.00 63.10  ? 350  ALA D O   1 
ATOM   10512 C CB  . ALA D 1 275 ? -59.807 25.465  63.606  1.00 38.69  ? 350  ALA D CB  1 
ATOM   10513 N N   . LEU D 1 276 ? -61.943 26.376  61.449  1.00 41.68  ? 351  LEU D N   1 
ATOM   10514 C CA  . LEU D 1 276 ? -63.042 27.258  61.059  1.00 46.30  ? 351  LEU D CA  1 
ATOM   10515 C C   . LEU D 1 276 ? -64.254 26.466  60.583  1.00 51.42  ? 351  LEU D C   1 
ATOM   10516 O O   . LEU D 1 276 ? -65.399 26.840  60.874  1.00 55.43  ? 351  LEU D O   1 
ATOM   10517 C CB  . LEU D 1 276 ? -62.587 28.223  59.967  1.00 46.22  ? 351  LEU D CB  1 
ATOM   10518 C CG  . LEU D 1 276 ? -61.632 29.336  60.385  1.00 42.61  ? 351  LEU D CG  1 
ATOM   10519 C CD1 . LEU D 1 276 ? -61.194 30.119  59.165  1.00 48.45  ? 351  LEU D CD1 1 
ATOM   10520 C CD2 . LEU D 1 276 ? -62.296 30.244  61.404  1.00 44.08  ? 351  LEU D CD2 1 
ATOM   10521 N N   . GLN D 1 277 ? -64.020 25.393  59.821  1.00 48.67  ? 352  GLN D N   1 
ATOM   10522 C CA  . GLN D 1 277 ? -65.116 24.559  59.337  1.00 56.16  ? 352  GLN D CA  1 
ATOM   10523 C C   . GLN D 1 277 ? -65.931 24.006  60.496  1.00 55.07  ? 352  GLN D C   1 
ATOM   10524 O O   . GLN D 1 277 ? -67.168 23.931  60.424  1.00 49.05  ? 352  GLN D O   1 
ATOM   10525 C CB  . GLN D 1 277 ? -64.561 23.415  58.490  1.00 48.11  ? 352  GLN D CB  1 
ATOM   10526 C CG  . GLN D 1 277 ? -64.302 23.768  57.038  1.00 53.17  ? 352  GLN D CG  1 
ATOM   10527 C CD  . GLN D 1 277 ? -63.322 22.812  56.385  1.00 53.09  ? 352  GLN D CD  1 
ATOM   10528 O OE1 . GLN D 1 277 ? -62.601 22.084  57.069  1.00 49.00  ? 352  GLN D OE1 1 
ATOM   10529 N NE2 . GLN D 1 277 ? -63.291 22.807  55.058  1.00 59.64  ? 352  GLN D NE2 1 
ATOM   10530 N N   . GLY D 1 278 ? -65.245 23.604  61.568  1.00 55.56  ? 353  GLY D N   1 
ATOM   10531 C CA  . GLY D 1 278 ? -65.954 23.149  62.754  1.00 64.15  ? 353  GLY D CA  1 
ATOM   10532 C C   . GLY D 1 278 ? -66.989 24.142  63.249  1.00 58.95  ? 353  GLY D C   1 
ATOM   10533 O O   . GLY D 1 278 ? -68.102 23.760  63.623  1.00 65.95  ? 353  GLY D O   1 
ATOM   10534 N N   . LEU D 1 279 ? -66.644 25.433  63.242  1.00 60.40  ? 354  LEU D N   1 
ATOM   10535 C CA  . LEU D 1 279 ? -67.559 26.460  63.731  1.00 54.94  ? 354  LEU D CA  1 
ATOM   10536 C C   . LEU D 1 279 ? -68.649 26.783  62.718  1.00 53.81  ? 354  LEU D C   1 
ATOM   10537 O O   . LEU D 1 279 ? -69.814 26.957  63.090  1.00 74.68  ? 354  LEU D O   1 
ATOM   10538 C CB  . LEU D 1 279 ? -66.781 27.729  64.082  1.00 50.96  ? 354  LEU D CB  1 
ATOM   10539 C CG  . LEU D 1 279 ? -65.526 27.517  64.925  1.00 51.17  ? 354  LEU D CG  1 
ATOM   10540 C CD1 . LEU D 1 279 ? -64.667 28.774  64.955  1.00 59.49  ? 354  LEU D CD1 1 
ATOM   10541 C CD2 . LEU D 1 279 ? -65.903 27.081  66.331  1.00 33.81  ? 354  LEU D CD2 1 
ATOM   10542 N N   . TYR D 1 280 ? -68.293 26.874  61.436  1.00 55.68  ? 355  TYR D N   1 
ATOM   10543 C CA  . TYR D 1 280 ? -69.284 27.233  60.427  1.00 55.14  ? 355  TYR D CA  1 
ATOM   10544 C C   . TYR D 1 280 ? -70.283 26.112  60.180  1.00 58.50  ? 355  TYR D C   1 
ATOM   10545 O O   . TYR D 1 280 ? -71.357 26.366  59.622  1.00 58.45  ? 355  TYR D O   1 
ATOM   10546 C CB  . TYR D 1 280 ? -68.589 27.631  59.126  1.00 57.86  ? 355  TYR D CB  1 
ATOM   10547 C CG  . TYR D 1 280 ? -67.976 29.004  59.209  1.00 51.80  ? 355  TYR D CG  1 
ATOM   10548 C CD1 . TYR D 1 280 ? -68.749 30.145  59.047  1.00 56.58  ? 355  TYR D CD1 1 
ATOM   10549 C CD2 . TYR D 1 280 ? -66.634 29.161  59.501  1.00 56.35  ? 355  TYR D CD2 1 
ATOM   10550 C CE1 . TYR D 1 280 ? -68.186 31.402  59.141  1.00 38.37  ? 355  TYR D CE1 1 
ATOM   10551 C CE2 . TYR D 1 280 ? -66.065 30.405  59.598  1.00 63.93  ? 355  TYR D CE2 1 
ATOM   10552 C CZ  . TYR D 1 280 ? -66.842 31.524  59.419  1.00 48.02  ? 355  TYR D CZ  1 
ATOM   10553 O OH  . TYR D 1 280 ? -66.252 32.761  59.524  1.00 48.41  ? 355  TYR D OH  1 
ATOM   10554 N N   . TYR D 1 281 ? -69.954 24.882  60.582  1.00 60.86  ? 356  TYR D N   1 
ATOM   10555 C CA  . TYR D 1 281 ? -70.929 23.798  60.508  1.00 71.34  ? 356  TYR D CA  1 
ATOM   10556 C C   . TYR D 1 281 ? -72.097 24.010  61.465  1.00 79.26  ? 356  TYR D C   1 
ATOM   10557 O O   . TYR D 1 281 ? -73.192 23.489  61.224  1.00 70.97  ? 356  TYR D O   1 
ATOM   10558 C CB  . TYR D 1 281 ? -70.240 22.468  60.806  1.00 67.69  ? 356  TYR D CB  1 
ATOM   10559 C CG  . TYR D 1 281 ? -71.087 21.255  60.508  1.00 82.63  ? 356  TYR D CG  1 
ATOM   10560 C CD1 . TYR D 1 281 ? -71.465 20.945  59.208  1.00 103.31 ? 356  TYR D CD1 1 
ATOM   10561 C CD2 . TYR D 1 281 ? -71.516 20.422  61.533  1.00 75.02  ? 356  TYR D CD2 1 
ATOM   10562 C CE1 . TYR D 1 281 ? -72.242 19.833  58.938  1.00 108.82 ? 356  TYR D CE1 1 
ATOM   10563 C CE2 . TYR D 1 281 ? -72.291 19.312  61.274  1.00 87.56  ? 356  TYR D CE2 1 
ATOM   10564 C CZ  . TYR D 1 281 ? -72.653 19.021  59.976  1.00 105.62 ? 356  TYR D CZ  1 
ATOM   10565 O OH  . TYR D 1 281 ? -73.427 17.913  59.720  1.00 98.89  ? 356  TYR D OH  1 
ATOM   10566 N N   . ASN D 1 282 ? -71.885 24.774  62.543  1.00 81.30  ? 357  ASN D N   1 
ATOM   10567 C CA  . ASN D 1 282 ? -72.882 24.878  63.607  1.00 68.31  ? 357  ASN D CA  1 
ATOM   10568 C C   . ASN D 1 282 ? -74.216 25.407  63.103  1.00 83.65  ? 357  ASN D C   1 
ATOM   10569 O O   . ASN D 1 282 ? -75.262 25.095  63.684  1.00 102.07 ? 357  ASN D O   1 
ATOM   10570 C CB  . ASN D 1 282 ? -72.361 25.778  64.727  1.00 71.91  ? 357  ASN D CB  1 
ATOM   10571 C CG  . ASN D 1 282 ? -72.805 25.315  66.093  1.00 93.36  ? 357  ASN D CG  1 
ATOM   10572 O OD1 . ASN D 1 282 ? -73.677 24.454  66.214  1.00 72.24  ? 357  ASN D OD1 1 
ATOM   10573 N ND2 . ASN D 1 282 ? -72.211 25.885  67.135  1.00 119.06 ? 357  ASN D ND2 1 
ATOM   10574 N N   . LYS D 1 283 ? -74.202 26.215  62.045  1.00 83.52  ? 358  LYS D N   1 
ATOM   10575 C CA  . LYS D 1 283 ? -75.389 26.830  61.458  1.00 88.49  ? 358  LYS D CA  1 
ATOM   10576 C C   . LYS D 1 283 ? -76.120 27.747  62.429  1.00 82.02  ? 358  LYS D C   1 
ATOM   10577 O O   . LYS D 1 283 ? -77.212 28.233  62.111  1.00 87.84  ? 358  LYS D O   1 
ATOM   10578 C CB  . LYS D 1 283 ? -76.357 25.776  60.901  1.00 72.69  ? 358  LYS D CB  1 
ATOM   10579 C CG  . LYS D 1 283 ? -75.992 25.290  59.506  1.00 115.85 ? 358  LYS D CG  1 
ATOM   10580 C CD  . LYS D 1 283 ? -76.030 26.428  58.495  1.00 124.20 ? 358  LYS D CD  1 
ATOM   10581 C CE  . LYS D 1 283 ? -77.440 26.970  58.325  1.00 105.50 ? 358  LYS D CE  1 
ATOM   10582 N NZ  . LYS D 1 283 ? -78.067 26.493  57.061  1.00 112.32 ? 358  LYS D NZ  1 
ATOM   10583 N N   . GLU D 1 284 ? -75.549 28.000  63.606  1.00 85.59  ? 359  GLU D N   1 
ATOM   10584 C CA  . GLU D 1 284 ? -76.068 29.040  64.481  1.00 82.22  ? 359  GLU D CA  1 
ATOM   10585 C C   . GLU D 1 284 ? -75.699 30.430  63.999  1.00 110.37 ? 359  GLU D C   1 
ATOM   10586 O O   . GLU D 1 284 ? -76.058 31.410  64.659  1.00 140.42 ? 359  GLU D O   1 
ATOM   10587 C CB  . GLU D 1 284 ? -75.564 28.845  65.912  1.00 64.08  ? 359  GLU D CB  1 
ATOM   10588 C CG  . GLU D 1 284 ? -75.486 27.400  66.346  1.00 89.68  ? 359  GLU D CG  1 
ATOM   10589 C CD  . GLU D 1 284 ? -76.850 26.803  66.637  1.00 107.59 ? 359  GLU D CD  1 
ATOM   10590 O OE1 . GLU D 1 284 ? -77.721 27.532  67.158  1.00 114.10 ? 359  GLU D OE1 1 
ATOM   10591 O OE2 . GLU D 1 284 ? -77.051 25.605  66.345  1.00 114.86 ? 359  GLU D OE2 1 
ATOM   10592 N N   . LEU D 1 285 ? -74.982 30.536  62.879  1.00 103.49 ? 360  LEU D N   1 
ATOM   10593 C CA  . LEU D 1 285 ? -74.723 31.821  62.240  1.00 85.45  ? 360  LEU D CA  1 
ATOM   10594 C C   . LEU D 1 285 ? -73.914 32.719  63.161  1.00 86.14  ? 360  LEU D C   1 
ATOM   10595 O O   . LEU D 1 285 ? -73.963 33.946  63.044  1.00 80.38  ? 360  LEU D O   1 
ATOM   10596 C CB  . LEU D 1 285 ? -76.037 32.499  61.853  1.00 87.68  ? 360  LEU D CB  1 
ATOM   10597 C CG  . LEU D 1 285 ? -76.999 31.569  61.119  1.00 118.13 ? 360  LEU D CG  1 
ATOM   10598 C CD1 . LEU D 1 285 ? -78.158 32.357  60.621  1.00 110.18 ? 360  LEU D CD1 1 
ATOM   10599 C CD2 . LEU D 1 285 ? -76.306 30.867  59.971  1.00 121.30 ? 360  LEU D CD2 1 
ATOM   10600 N N   . ASN D 1 286 ? -73.159 32.091  64.066  1.00 64.42  ? 361  ASN D N   1 
ATOM   10601 C CA  . ASN D 1 286 ? -72.606 32.716  65.264  1.00 98.74  ? 361  ASN D CA  1 
ATOM   10602 C C   . ASN D 1 286 ? -72.185 34.154  65.017  1.00 101.76 ? 361  ASN D C   1 
ATOM   10603 O O   . ASN D 1 286 ? -71.356 34.430  64.146  1.00 101.80 ? 361  ASN D O   1 
ATOM   10604 C CB  . ASN D 1 286 ? -71.417 31.897  65.761  1.00 93.43  ? 361  ASN D CB  1 
ATOM   10605 C CG  . ASN D 1 286 ? -71.712 30.415  65.800  1.00 80.00  ? 361  ASN D CG  1 
ATOM   10606 O OD1 . ASN D 1 286 ? -72.679 29.978  66.419  1.00 72.06  ? 361  ASN D OD1 1 
ATOM   10607 N ND2 . ASN D 1 286 ? -70.884 29.631  65.125  1.00 106.98 ? 361  ASN D ND2 1 
ATOM   10608 N N   . SER D 1 287 ? -72.773 35.075  65.785  1.00 94.92  ? 362  SER D N   1 
ATOM   10609 C CA  . SER D 1 287 ? -72.593 36.497  65.511  1.00 88.27  ? 362  SER D CA  1 
ATOM   10610 C C   . SER D 1 287 ? -71.125 36.896  65.541  1.00 105.60 ? 362  SER D C   1 
ATOM   10611 O O   . SER D 1 287 ? -70.735 37.880  64.901  1.00 143.04 ? 362  SER D O   1 
ATOM   10612 C CB  . SER D 1 287 ? -73.393 37.327  66.514  1.00 100.98 ? 362  SER D CB  1 
ATOM   10613 O OG  . SER D 1 287 ? -74.638 36.714  66.804  1.00 92.57  ? 362  SER D OG  1 
ATOM   10614 N N   . LYS D 1 288 ? -70.300 36.146  66.274  1.00 85.75  ? 363  LYS D N   1 
ATOM   10615 C CA  . LYS D 1 288 ? -68.862 36.376  66.242  1.00 97.81  ? 363  LYS D CA  1 
ATOM   10616 C C   . LYS D 1 288 ? -68.300 36.002  64.875  1.00 95.68  ? 363  LYS D C   1 
ATOM   10617 O O   . LYS D 1 288 ? -67.423 36.695  64.326  1.00 95.76  ? 363  LYS D O   1 
ATOM   10618 C CB  . LYS D 1 288 ? -68.200 35.555  67.349  1.00 102.53 ? 363  LYS D CB  1 
ATOM   10619 C CG  . LYS D 1 288 ? -68.166 36.247  68.706  1.00 108.12 ? 363  LYS D CG  1 
ATOM   10620 C CD  . LYS D 1 288 ? -67.813 37.721  68.607  1.00 101.32 ? 363  LYS D CD  1 
ATOM   10621 C CE  . LYS D 1 288 ? -67.170 38.205  69.898  1.00 100.80 ? 363  LYS D CE  1 
ATOM   10622 N NZ  . LYS D 1 288 ? -67.638 37.414  71.071  1.00 111.44 ? 363  LYS D NZ  1 
ATOM   10623 N N   . LEU D 1 289 ? -68.826 34.918  64.300  1.00 85.55  ? 364  LEU D N   1 
ATOM   10624 C CA  . LEU D 1 289 ? -68.431 34.518  62.961  1.00 77.65  ? 364  LEU D CA  1 
ATOM   10625 C C   . LEU D 1 289 ? -68.850 35.538  61.916  1.00 76.89  ? 364  LEU D C   1 
ATOM   10626 O O   . LEU D 1 289 ? -68.244 35.577  60.851  1.00 68.81  ? 364  LEU D O   1 
ATOM   10627 C CB  . LEU D 1 289 ? -69.014 33.149  62.596  1.00 65.97  ? 364  LEU D CB  1 
ATOM   10628 C CG  . LEU D 1 289 ? -68.434 31.919  63.296  1.00 51.67  ? 364  LEU D CG  1 
ATOM   10629 C CD1 . LEU D 1 289 ? -68.923 30.645  62.620  1.00 42.37  ? 364  LEU D CD1 1 
ATOM   10630 C CD2 . LEU D 1 289 ? -66.922 31.974  63.327  1.00 56.18  ? 364  LEU D CD2 1 
ATOM   10631 N N   . GLU D 1 290 ? -69.859 36.371  62.187  1.00 78.95  ? 365  GLU D N   1 
ATOM   10632 C CA  . GLU D 1 290 ? -70.193 37.439  61.248  1.00 69.66  ? 365  GLU D CA  1 
ATOM   10633 C C   . GLU D 1 290 ? -69.016 38.393  61.082  1.00 62.38  ? 365  GLU D C   1 
ATOM   10634 O O   . GLU D 1 290 ? -68.584 38.692  59.958  1.00 75.62  ? 365  GLU D O   1 
ATOM   10635 C CB  . GLU D 1 290 ? -71.429 38.202  61.725  1.00 75.40  ? 365  GLU D CB  1 
ATOM   10636 C CG  . GLU D 1 290 ? -72.728 37.416  61.712  1.00 99.98  ? 365  GLU D CG  1 
ATOM   10637 C CD  . GLU D 1 290 ? -73.839 38.138  62.452  1.00 102.25 ? 365  GLU D CD  1 
ATOM   10638 O OE1 . GLU D 1 290 ? -73.638 39.319  62.806  1.00 77.08  ? 365  GLU D OE1 1 
ATOM   10639 O OE2 . GLU D 1 290 ? -74.911 37.534  62.671  1.00 107.67 ? 365  GLU D OE2 1 
ATOM   10640 N N   . LEU D 1 291 ? -68.484 38.877  62.204  1.00 64.84  ? 366  LEU D N   1 
ATOM   10641 C CA  . LEU D 1 291 ? -67.339 39.775  62.165  1.00 72.85  ? 366  LEU D CA  1 
ATOM   10642 C C   . LEU D 1 291 ? -66.127 39.078  61.553  1.00 70.67  ? 366  LEU D C   1 
ATOM   10643 O O   . LEU D 1 291 ? -65.410 39.663  60.725  1.00 57.30  ? 366  LEU D O   1 
ATOM   10644 C CB  . LEU D 1 291 ? -67.039 40.263  63.583  1.00 77.14  ? 366  LEU D CB  1 
ATOM   10645 C CG  . LEU D 1 291 ? -66.477 41.664  63.792  1.00 79.04  ? 366  LEU D CG  1 
ATOM   10646 C CD1 . LEU D 1 291 ? -67.374 42.672  63.102  1.00 46.28  ? 366  LEU D CD1 1 
ATOM   10647 C CD2 . LEU D 1 291 ? -66.370 41.971  65.281  1.00 66.19  ? 366  LEU D CD2 1 
ATOM   10648 N N   . PHE D 1 292 ? -65.902 37.813  61.927  1.00 74.09  ? 367  PHE D N   1 
ATOM   10649 C CA  . PHE D 1 292 ? -64.767 37.085  61.361  1.00 60.08  ? 367  PHE D CA  1 
ATOM   10650 C C   . PHE D 1 292 ? -64.909 36.902  59.849  1.00 62.24  ? 367  PHE D C   1 
ATOM   10651 O O   . PHE D 1 292 ? -63.925 37.033  59.109  1.00 65.35  ? 367  PHE D O   1 
ATOM   10652 C CB  . PHE D 1 292 ? -64.596 35.733  62.058  1.00 60.89  ? 367  PHE D CB  1 
ATOM   10653 C CG  . PHE D 1 292 ? -63.340 35.002  61.665  1.00 58.19  ? 367  PHE D CG  1 
ATOM   10654 C CD1 . PHE D 1 292 ? -63.298 34.237  60.509  1.00 49.54  ? 367  PHE D CD1 1 
ATOM   10655 C CD2 . PHE D 1 292 ? -62.194 35.096  62.441  1.00 61.05  ? 367  PHE D CD2 1 
ATOM   10656 C CE1 . PHE D 1 292 ? -62.146 33.571  60.137  1.00 49.13  ? 367  PHE D CE1 1 
ATOM   10657 C CE2 . PHE D 1 292 ? -61.034 34.429  62.074  1.00 62.48  ? 367  PHE D CE2 1 
ATOM   10658 C CZ  . PHE D 1 292 ? -61.012 33.666  60.920  1.00 60.26  ? 367  PHE D CZ  1 
ATOM   10659 N N   . THR D 1 293 ? -66.119 36.586  59.373  1.00 52.63  ? 368  THR D N   1 
ATOM   10660 C CA  . THR D 1 293 ? -66.364 36.473  57.938  1.00 55.55  ? 368  THR D CA  1 
ATOM   10661 C C   . THR D 1 293 ? -66.060 37.778  57.226  1.00 68.24  ? 368  THR D C   1 
ATOM   10662 O O   . THR D 1 293 ? -65.308 37.797  56.250  1.00 81.66  ? 368  THR D O   1 
ATOM   10663 C CB  . THR D 1 293 ? -67.812 36.058  57.653  1.00 53.73  ? 368  THR D CB  1 
ATOM   10664 O OG1 . THR D 1 293 ? -68.714 36.926  58.353  1.00 106.81 ? 368  THR D OG1 1 
ATOM   10665 C CG2 . THR D 1 293 ? -68.067 34.609  58.006  1.00 43.78  ? 368  THR D CG2 1 
ATOM   10666 N N   . SER D 1 294 ? -66.652 38.881  57.684  1.00 71.64  ? 369  SER D N   1 
ATOM   10667 C CA  . SER D 1 294 ? -66.388 40.148  57.011  1.00 68.55  ? 369  SER D CA  1 
ATOM   10668 C C   . SER D 1 294 ? -64.897 40.472  56.994  1.00 65.99  ? 369  SER D C   1 
ATOM   10669 O O   . SER D 1 294 ? -64.401 41.049  56.018  1.00 70.47  ? 369  SER D O   1 
ATOM   10670 C CB  . SER D 1 294 ? -67.182 41.277  57.667  1.00 70.20  ? 369  SER D CB  1 
ATOM   10671 O OG  . SER D 1 294 ? -67.205 41.140  59.075  1.00 87.07  ? 369  SER D OG  1 
ATOM   10672 N N   . ARG D 1 295 ? -64.156 40.065  58.031  1.00 53.68  ? 370  ARG D N   1 
ATOM   10673 C CA  . ARG D 1 295 ? -62.739 40.419  58.089  1.00 62.51  ? 370  ARG D CA  1 
ATOM   10674 C C   . ARG D 1 295 ? -61.862 39.522  57.212  1.00 70.30  ? 370  ARG D C   1 
ATOM   10675 O O   . ARG D 1 295 ? -60.880 40.004  56.634  1.00 82.15  ? 370  ARG D O   1 
ATOM   10676 C CB  . ARG D 1 295 ? -62.259 40.396  59.542  1.00 72.44  ? 370  ARG D CB  1 
ATOM   10677 C CG  . ARG D 1 295 ? -60.855 40.957  59.780  1.00 64.61  ? 370  ARG D CG  1 
ATOM   10678 C CD  . ARG D 1 295 ? -60.694 42.417  59.374  1.00 73.19  ? 370  ARG D CD  1 
ATOM   10679 N NE  . ARG D 1 295 ? -59.308 42.844  59.531  1.00 101.18 ? 370  ARG D NE  1 
ATOM   10680 C CZ  . ARG D 1 295 ? -58.907 43.856  60.289  1.00 105.86 ? 370  ARG D CZ  1 
ATOM   10681 N NH1 . ARG D 1 295 ? -59.771 44.622  60.936  1.00 109.42 ? 370  ARG D NH1 1 
ATOM   10682 N NH2 . ARG D 1 295 ? -57.606 44.113  60.393  1.00 112.76 ? 370  ARG D NH2 1 
ATOM   10683 N N   . PHE D 1 296 ? -62.179 38.226  57.089  1.00 68.18  ? 371  PHE D N   1 
ATOM   10684 C CA  . PHE D 1 296 ? -61.273 37.284  56.426  1.00 65.01  ? 371  PHE D CA  1 
ATOM   10685 C C   . PHE D 1 296 ? -61.911 36.556  55.236  1.00 69.27  ? 371  PHE D C   1 
ATOM   10686 O O   . PHE D 1 296 ? -61.370 35.540  54.758  1.00 78.75  ? 371  PHE D O   1 
ATOM   10687 C CB  . PHE D 1 296 ? -60.730 36.285  57.448  1.00 54.42  ? 371  PHE D CB  1 
ATOM   10688 C CG  . PHE D 1 296 ? -60.036 36.931  58.623  1.00 55.08  ? 371  PHE D CG  1 
ATOM   10689 C CD1 . PHE D 1 296 ? -58.722 37.358  58.519  1.00 57.69  ? 371  PHE D CD1 1 
ATOM   10690 C CD2 . PHE D 1 296 ? -60.694 37.099  59.833  1.00 64.10  ? 371  PHE D CD2 1 
ATOM   10691 C CE1 . PHE D 1 296 ? -58.077 37.949  59.595  1.00 61.71  ? 371  PHE D CE1 1 
ATOM   10692 C CE2 . PHE D 1 296 ? -60.053 37.688  60.914  1.00 63.47  ? 371  PHE D CE2 1 
ATOM   10693 C CZ  . PHE D 1 296 ? -58.744 38.113  60.794  1.00 58.68  ? 371  PHE D CZ  1 
ATOM   10694 N N   . LYS D 1 297 ? -63.034 37.074  54.731  1.00 60.37  ? 372  LYS D N   1 
ATOM   10695 C CA  . LYS D 1 297 ? -63.695 36.485  53.572  1.00 65.77  ? 372  LYS D CA  1 
ATOM   10696 C C   . LYS D 1 297 ? -62.770 36.441  52.368  1.00 80.87  ? 372  LYS D C   1 
ATOM   10697 O O   . LYS D 1 297 ? -62.698 35.429  51.659  1.00 74.68  ? 372  LYS D O   1 
ATOM   10698 C CB  . LYS D 1 297 ? -64.948 37.291  53.236  1.00 63.76  ? 372  LYS D CB  1 
ATOM   10699 C CG  . LYS D 1 297 ? -66.078 36.493  52.625  1.00 78.53  ? 372  LYS D CG  1 
ATOM   10700 C CD  . LYS D 1 297 ? -66.570 37.168  51.357  1.00 92.82  ? 372  LYS D CD  1 
ATOM   10701 C CE  . LYS D 1 297 ? -67.069 38.579  51.618  1.00 87.66  ? 372  LYS D CE  1 
ATOM   10702 N NZ  . LYS D 1 297 ? -67.963 39.048  50.524  1.00 101.22 ? 372  LYS D NZ  1 
ATOM   10703 N N   . ASP D 1 298 ? -62.083 37.552  52.103  1.00 86.30  ? 373  ASP D N   1 
ATOM   10704 C CA  . ASP D 1 298 ? -61.217 37.633  50.935  1.00 89.15  ? 373  ASP D CA  1 
ATOM   10705 C C   . ASP D 1 298 ? -60.062 36.651  51.043  1.00 75.50  ? 373  ASP D C   1 
ATOM   10706 O O   . ASP D 1 298 ? -59.664 36.039  50.045  1.00 76.20  ? 373  ASP D O   1 
ATOM   10707 C CB  . ASP D 1 298 ? -60.699 39.060  50.774  1.00 106.25 ? 373  ASP D CB  1 
ATOM   10708 C CG  . ASP D 1 298 ? -61.811 40.086  50.829  1.00 116.11 ? 373  ASP D CG  1 
ATOM   10709 O OD1 . ASP D 1 298 ? -61.740 40.991  51.686  1.00 143.02 ? 373  ASP D OD1 1 
ATOM   10710 O OD2 . ASP D 1 298 ? -62.766 39.977  50.031  1.00 140.75 ? 373  ASP D OD2 1 
ATOM   10711 N N   . ARG D 1 299 ? -59.520 36.478  52.250  1.00 70.14  ? 374  ARG D N   1 
ATOM   10712 C CA  . ARG D 1 299 ? -58.471 35.487  52.452  1.00 68.65  ? 374  ARG D CA  1 
ATOM   10713 C C   . ARG D 1 299 ? -58.974 34.084  52.146  1.00 73.90  ? 374  ARG D C   1 
ATOM   10714 O O   . ARG D 1 299 ? -58.279 33.304  51.490  1.00 73.72  ? 374  ARG D O   1 
ATOM   10715 C CB  . ARG D 1 299 ? -57.935 35.569  53.881  1.00 71.66  ? 374  ARG D CB  1 
ATOM   10716 C CG  . ARG D 1 299 ? -56.767 34.638  54.185  1.00 74.43  ? 374  ARG D CG  1 
ATOM   10717 C CD  . ARG D 1 299 ? -55.615 34.740  53.188  1.00 77.93  ? 374  ARG D CD  1 
ATOM   10718 N NE  . ARG D 1 299 ? -54.664 33.657  53.410  1.00 79.77  ? 374  ARG D NE  1 
ATOM   10719 C CZ  . ARG D 1 299 ? -54.177 32.869  52.462  1.00 72.47  ? 374  ARG D CZ  1 
ATOM   10720 N NH1 . ARG D 1 299 ? -54.445 33.076  51.183  1.00 59.43  ? 374  ARG D NH1 1 
ATOM   10721 N NH2 . ARG D 1 299 ? -53.420 31.833  52.807  1.00 69.21  ? 374  ARG D NH2 1 
ATOM   10722 N N   . ILE D 1 300 ? -60.183 33.743  52.601  1.00 70.21  ? 375  ILE D N   1 
ATOM   10723 C CA  . ILE D 1 300 ? -60.717 32.408  52.308  1.00 72.74  ? 375  ILE D CA  1 
ATOM   10724 C C   . ILE D 1 300 ? -60.916 32.226  50.800  1.00 64.29  ? 375  ILE D C   1 
ATOM   10725 O O   . ILE D 1 300 ? -60.526 31.201  50.209  1.00 61.18  ? 375  ILE D O   1 
ATOM   10726 C CB  . ILE D 1 300 ? -62.023 32.171  53.089  1.00 64.87  ? 375  ILE D CB  1 
ATOM   10727 C CG1 . ILE D 1 300 ? -61.772 32.334  54.589  1.00 57.33  ? 375  ILE D CG1 1 
ATOM   10728 C CG2 . ILE D 1 300 ? -62.575 30.786  52.800  1.00 51.71  ? 375  ILE D CG2 1 
ATOM   10729 C CD1 . ILE D 1 300 ? -63.021 32.565  55.398  1.00 60.27  ? 375  ILE D CD1 1 
ATOM   10730 N N   . VAL D 1 301 ? -61.528 33.225  50.156  1.00 62.25  ? 376  VAL D N   1 
ATOM   10731 C CA  . VAL D 1 301 ? -61.774 33.150  48.718  1.00 58.05  ? 376  VAL D CA  1 
ATOM   10732 C C   . VAL D 1 301 ? -60.462 32.984  47.961  1.00 61.33  ? 376  VAL D C   1 
ATOM   10733 O O   . VAL D 1 301 ? -60.382 32.225  46.988  1.00 76.97  ? 376  VAL D O   1 
ATOM   10734 C CB  . VAL D 1 301 ? -62.556 34.391  48.245  1.00 66.16  ? 376  VAL D CB  1 
ATOM   10735 C CG1 . VAL D 1 301 ? -62.639 34.428  46.729  1.00 71.13  ? 376  VAL D CG1 1 
ATOM   10736 C CG2 . VAL D 1 301 ? -63.950 34.397  48.850  1.00 72.04  ? 376  VAL D CG2 1 
ATOM   10737 N N   . SER D 1 302 ? -59.409 33.671  48.407  1.00 55.47  ? 377  SER D N   1 
ATOM   10738 C CA  . SER D 1 302 ? -58.099 33.513  47.786  1.00 60.07  ? 377  SER D CA  1 
ATOM   10739 C C   . SER D 1 302 ? -57.522 32.127  48.045  1.00 60.22  ? 377  SER D C   1 
ATOM   10740 O O   . SER D 1 302 ? -56.878 31.542  47.165  1.00 63.79  ? 377  SER D O   1 
ATOM   10741 C CB  . SER D 1 302 ? -57.151 34.592  48.303  1.00 59.29  ? 377  SER D CB  1 
ATOM   10742 O OG  . SER D 1 302 ? -56.632 34.240  49.575  1.00 56.14  ? 377  SER D OG  1 
ATOM   10743 N N   . MET D 1 303 ? -57.732 31.594  49.251  1.00 65.74  ? 378  MET D N   1 
ATOM   10744 C CA  . MET D 1 303 ? -57.276 30.251  49.590  1.00 64.92  ? 378  MET D CA  1 
ATOM   10745 C C   . MET D 1 303 ? -57.911 29.184  48.718  1.00 57.24  ? 378  MET D C   1 
ATOM   10746 O O   . MET D 1 303 ? -57.363 28.081  48.612  1.00 68.38  ? 378  MET D O   1 
ATOM   10747 C CB  . MET D 1 303 ? -57.560 29.971  51.063  1.00 54.40  ? 378  MET D CB  1 
ATOM   10748 C CG  . MET D 1 303 ? -56.694 30.800  51.968  1.00 60.44  ? 378  MET D CG  1 
ATOM   10749 S SD  . MET D 1 303 ? -56.219 29.985  53.486  1.00 70.22  ? 378  MET D SD  1 
ATOM   10750 C CE  . MET D 1 303 ? -57.546 30.565  54.522  1.00 59.96  ? 378  MET D CE  1 
ATOM   10751 N N   . THR D 1 304 ? -59.059 29.479  48.106  1.00 51.86  ? 379  THR D N   1 
ATOM   10752 C CA  . THR D 1 304 ? -59.575 28.556  47.092  1.00 61.85  ? 379  THR D CA  1 
ATOM   10753 C C   . THR D 1 304 ? -58.548 28.265  45.994  1.00 65.87  ? 379  THR D C   1 
ATOM   10754 O O   . THR D 1 304 ? -58.618 27.214  45.348  1.00 68.17  ? 379  THR D O   1 
ATOM   10755 C CB  . THR D 1 304 ? -60.852 29.093  46.448  1.00 58.52  ? 379  THR D CB  1 
ATOM   10756 O OG1 . THR D 1 304 ? -60.546 30.278  45.703  1.00 65.35  ? 379  THR D OG1 1 
ATOM   10757 C CG2 . THR D 1 304 ? -61.898 29.395  47.505  1.00 61.64  ? 379  THR D CG2 1 
ATOM   10758 N N   . LEU D 1 305 ? -57.604 29.178  45.754  1.00 68.52  ? 380  LEU D N   1 
ATOM   10759 C CA  . LEU D 1 305 ? -56.514 28.969  44.800  1.00 69.04  ? 380  LEU D CA  1 
ATOM   10760 C C   . LEU D 1 305 ? -55.161 28.863  45.501  1.00 67.00  ? 380  LEU D C   1 
ATOM   10761 O O   . LEU D 1 305 ? -54.168 29.451  45.068  1.00 63.67  ? 380  LEU D O   1 
ATOM   10762 C CB  . LEU D 1 305 ? -56.477 30.078  43.751  1.00 68.95  ? 380  LEU D CB  1 
ATOM   10763 C CG  . LEU D 1 305 ? -57.180 29.807  42.417  1.00 69.64  ? 380  LEU D CG  1 
ATOM   10764 C CD1 . LEU D 1 305 ? -56.946 30.952  41.442  1.00 82.54  ? 380  LEU D CD1 1 
ATOM   10765 C CD2 . LEU D 1 305 ? -56.702 28.493  41.820  1.00 72.91  ? 380  LEU D CD2 1 
ATOM   10766 N N   . ASP D 1 306 ? -55.112 28.098  46.587  1.00 66.93  ? 381  ASP D N   1 
ATOM   10767 C CA  . ASP D 1 306 ? -53.900 27.964  47.381  1.00 66.64  ? 381  ASP D CA  1 
ATOM   10768 C C   . ASP D 1 306 ? -52.872 27.103  46.648  1.00 71.25  ? 381  ASP D C   1 
ATOM   10769 O O   . ASP D 1 306 ? -53.208 26.282  45.789  1.00 78.22  ? 381  ASP D O   1 
ATOM   10770 C CB  . ASP D 1 306 ? -54.238 27.357  48.745  1.00 65.46  ? 381  ASP D CB  1 
ATOM   10771 C CG  . ASP D 1 306 ? -53.105 27.485  49.745  1.00 73.71  ? 381  ASP D CG  1 
ATOM   10772 O OD1 . ASP D 1 306 ? -52.207 26.619  49.744  1.00 60.62  ? 381  ASP D OD1 1 
ATOM   10773 O OD2 . ASP D 1 306 ? -53.116 28.454  50.534  1.00 74.75  ? 381  ASP D OD2 1 
ATOM   10774 N N   . LYS D 1 307 ? -51.596 27.305  46.997  1.00 67.54  ? 382  LYS D N   1 
ATOM   10775 C CA  . LYS D 1 307 ? -50.525 26.501  46.409  1.00 64.92  ? 382  LYS D CA  1 
ATOM   10776 C C   . LYS D 1 307 ? -50.689 25.021  46.728  1.00 64.35  ? 382  LYS D C   1 
ATOM   10777 O O   . LYS D 1 307 ? -50.360 24.168  45.897  1.00 73.88  ? 382  LYS D O   1 
ATOM   10778 C CB  . LYS D 1 307 ? -49.164 27.002  46.896  1.00 77.30  ? 382  LYS D CB  1 
ATOM   10779 C CG  . LYS D 1 307 ? -48.579 28.137  46.068  1.00 84.92  ? 382  LYS D CG  1 
ATOM   10780 C CD  . LYS D 1 307 ? -48.007 27.619  44.756  1.00 97.64  ? 382  LYS D CD  1 
ATOM   10781 C CE  . LYS D 1 307 ? -46.813 28.447  44.301  1.00 95.32  ? 382  LYS D CE  1 
ATOM   10782 N NZ  . LYS D 1 307 ? -45.655 28.300  45.227  1.00 88.78  ? 382  LYS D NZ  1 
ATOM   10783 N N   . GLU D 1 308 ? -51.187 24.698  47.918  1.00 67.18  ? 383  GLU D N   1 
ATOM   10784 C CA  . GLU D 1 308 ? -51.503 23.323  48.287  1.00 70.08  ? 383  GLU D CA  1 
ATOM   10785 C C   . GLU D 1 308 ? -52.947 23.029  47.895  1.00 71.10  ? 383  GLU D C   1 
ATOM   10786 O O   . GLU D 1 308 ? -53.869 23.723  48.338  1.00 75.51  ? 383  GLU D O   1 
ATOM   10787 C CB  . GLU D 1 308 ? -51.292 23.097  49.784  1.00 76.26  ? 383  GLU D CB  1 
ATOM   10788 C CG  . GLU D 1 308 ? -49.915 22.568  50.164  1.00 82.78  ? 383  GLU D CG  1 
ATOM   10789 C CD  . GLU D 1 308 ? -48.784 23.402  49.596  1.00 91.07  ? 383  GLU D CD  1 
ATOM   10790 O OE1 . GLU D 1 308 ? -48.746 24.621  49.862  1.00 101.57 ? 383  GLU D OE1 1 
ATOM   10791 O OE2 . GLU D 1 308 ? -47.925 22.834  48.890  1.00 90.63  ? 383  GLU D OE2 1 
ATOM   10792 N N   . TYR D 1 309 ? -53.140 21.999  47.065  1.00 61.32  ? 384  TYR D N   1 
ATOM   10793 C CA  . TYR D 1 309 ? -54.479 21.679  46.575  1.00 72.42  ? 384  TYR D CA  1 
ATOM   10794 C C   . TYR D 1 309 ? -55.413 21.266  47.706  1.00 63.96  ? 384  TYR D C   1 
ATOM   10795 O O   . TYR D 1 309 ? -56.606 21.587  47.680  1.00 57.24  ? 384  TYR D O   1 
ATOM   10796 C CB  . TYR D 1 309 ? -54.404 20.578  45.517  1.00 79.42  ? 384  TYR D CB  1 
ATOM   10797 C CG  . TYR D 1 309 ? -54.242 21.082  44.100  1.00 66.07  ? 384  TYR D CG  1 
ATOM   10798 C CD1 . TYR D 1 309 ? -55.010 22.137  43.628  1.00 77.66  ? 384  TYR D CD1 1 
ATOM   10799 C CD2 . TYR D 1 309 ? -53.334 20.493  43.231  1.00 78.87  ? 384  TYR D CD2 1 
ATOM   10800 C CE1 . TYR D 1 309 ? -54.874 22.598  42.332  1.00 87.21  ? 384  TYR D CE1 1 
ATOM   10801 C CE2 . TYR D 1 309 ? -53.189 20.947  41.933  1.00 95.29  ? 384  TYR D CE2 1 
ATOM   10802 C CZ  . TYR D 1 309 ? -53.962 22.000  41.489  1.00 91.79  ? 384  TYR D CZ  1 
ATOM   10803 O OH  . TYR D 1 309 ? -53.824 22.457  40.198  1.00 90.38  ? 384  TYR D OH  1 
ATOM   10804 N N   . ASP D 1 310 ? -54.896 20.537  48.697  1.00 61.77  ? 385  ASP D N   1 
ATOM   10805 C CA  . ASP D 1 310 ? -55.724 20.122  49.827  1.00 68.82  ? 385  ASP D CA  1 
ATOM   10806 C C   . ASP D 1 310 ? -56.278 21.326  50.584  1.00 70.62  ? 385  ASP D C   1 
ATOM   10807 O O   . ASP D 1 310 ? -57.472 21.364  50.924  1.00 84.03  ? 385  ASP D O   1 
ATOM   10808 C CB  . ASP D 1 310 ? -54.910 19.207  50.743  1.00 83.26  ? 385  ASP D CB  1 
ATOM   10809 C CG  . ASP D 1 310 ? -53.574 19.817  51.143  1.00 88.45  ? 385  ASP D CG  1 
ATOM   10810 O OD1 . ASP D 1 310 ? -52.616 19.720  50.345  1.00 92.88  ? 385  ASP D OD1 1 
ATOM   10811 O OD2 . ASP D 1 310 ? -53.474 20.379  52.254  1.00 105.39 ? 385  ASP D OD2 1 
ATOM   10812 N N   . VAL D 1 311 ? -55.432 22.329  50.836  1.00 54.64  ? 386  VAL D N   1 
ATOM   10813 C CA  . VAL D 1 311 ? -55.892 23.561  51.469  1.00 60.25  ? 386  VAL D CA  1 
ATOM   10814 C C   . VAL D 1 311 ? -56.968 24.228  50.621  1.00 70.11  ? 386  VAL D C   1 
ATOM   10815 O O   . VAL D 1 311 ? -57.952 24.762  51.146  1.00 68.43  ? 386  VAL D O   1 
ATOM   10816 C CB  . VAL D 1 311 ? -54.702 24.506  51.718  1.00 45.33  ? 386  VAL D CB  1 
ATOM   10817 C CG1 . VAL D 1 311 ? -55.167 25.791  52.382  1.00 54.61  ? 386  VAL D CG1 1 
ATOM   10818 C CG2 . VAL D 1 311 ? -53.648 23.817  52.565  1.00 56.10  ? 386  VAL D CG2 1 
ATOM   10819 N N   . ALA D 1 312 ? -56.802 24.202  49.297  1.00 63.95  ? 387  ALA D N   1 
ATOM   10820 C CA  . ALA D 1 312 ? -57.782 24.826  48.413  1.00 59.08  ? 387  ALA D CA  1 
ATOM   10821 C C   . ALA D 1 312 ? -59.130 24.116  48.487  1.00 63.01  ? 387  ALA D C   1 
ATOM   10822 O O   . ALA D 1 312 ? -60.186 24.765  48.517  1.00 71.33  ? 387  ALA D O   1 
ATOM   10823 C CB  . ALA D 1 312 ? -57.253 24.836  46.980  1.00 57.07  ? 387  ALA D CB  1 
ATOM   10824 N N   . VAL D 1 313 ? -59.113 22.781  48.504  1.00 55.59  ? 388  VAL D N   1 
ATOM   10825 C CA  . VAL D 1 313 ? -60.354 22.020  48.633  1.00 54.60  ? 388  VAL D CA  1 
ATOM   10826 C C   . VAL D 1 313 ? -61.045 22.356  49.946  1.00 65.55  ? 388  VAL D C   1 
ATOM   10827 O O   . VAL D 1 313 ? -62.268 22.555  49.990  1.00 62.15  ? 388  VAL D O   1 
ATOM   10828 C CB  . VAL D 1 313 ? -60.076 20.509  48.513  1.00 53.55  ? 388  VAL D CB  1 
ATOM   10829 C CG1 . VAL D 1 313 ? -61.373 19.726  48.640  1.00 70.89  ? 388  VAL D CG1 1 
ATOM   10830 C CG2 . VAL D 1 313 ? -59.397 20.194  47.191  1.00 53.42  ? 388  VAL D CG2 1 
ATOM   10831 N N   . GLN D 1 314 ? -60.276 22.434  51.037  1.00 57.54  ? 389  GLN D N   1 
ATOM   10832 C CA  . GLN D 1 314 ? -60.881 22.788  52.320  1.00 58.63  ? 389  GLN D CA  1 
ATOM   10833 C C   . GLN D 1 314 ? -61.438 24.208  52.304  1.00 64.50  ? 389  GLN D C   1 
ATOM   10834 O O   . GLN D 1 314 ? -62.475 24.480  52.921  1.00 67.22  ? 389  GLN D O   1 
ATOM   10835 C CB  . GLN D 1 314 ? -59.874 22.605  53.453  1.00 59.26  ? 389  GLN D CB  1 
ATOM   10836 C CG  . GLN D 1 314 ? -59.559 21.152  53.716  1.00 68.45  ? 389  GLN D CG  1 
ATOM   10837 C CD  . GLN D 1 314 ? -60.811 20.293  53.664  1.00 48.96  ? 389  GLN D CD  1 
ATOM   10838 O OE1 . GLN D 1 314 ? -61.692 20.412  54.514  1.00 52.30  ? 389  GLN D OE1 1 
ATOM   10839 N NE2 . GLN D 1 314 ? -60.896 19.427  52.660  1.00 47.59  ? 389  GLN D NE2 1 
ATOM   10840 N N   . ALA D 1 315 ? -60.772 25.125  51.600  1.00 56.19  ? 390  ALA D N   1 
ATOM   10841 C CA  . ALA D 1 315 ? -61.276 26.493  51.515  1.00 52.85  ? 390  ALA D CA  1 
ATOM   10842 C C   . ALA D 1 315 ? -62.603 26.543  50.766  1.00 61.77  ? 390  ALA D C   1 
ATOM   10843 O O   . ALA D 1 315 ? -63.531 27.257  51.170  1.00 67.51  ? 390  ALA D O   1 
ATOM   10844 C CB  . ALA D 1 315 ? -60.239 27.392  50.843  1.00 61.63  ? 390  ALA D CB  1 
ATOM   10845 N N   . ILE D 1 316 ? -62.712 25.790  49.671  1.00 61.27  ? 391  ILE D N   1 
ATOM   10846 C CA  . ILE D 1 316 ? -63.976 25.735  48.939  1.00 58.29  ? 391  ILE D CA  1 
ATOM   10847 C C   . ILE D 1 316 ? -65.070 25.120  49.807  1.00 65.83  ? 391  ILE D C   1 
ATOM   10848 O O   . ILE D 1 316 ? -66.214 25.594  49.818  1.00 69.17  ? 391  ILE D O   1 
ATOM   10849 C CB  . ILE D 1 316 ? -63.802 24.971  47.615  1.00 63.93  ? 391  ILE D CB  1 
ATOM   10850 C CG1 . ILE D 1 316 ? -62.707 25.616  46.768  1.00 65.59  ? 391  ILE D CG1 1 
ATOM   10851 C CG2 . ILE D 1 316 ? -65.108 24.953  46.836  1.00 61.76  ? 391  ILE D CG2 1 
ATOM   10852 C CD1 . ILE D 1 316 ? -62.073 24.668  45.783  1.00 67.47  ? 391  ILE D CD1 1 
ATOM   10853 N N   . LYS D 1 317 ? -64.738 24.055  50.546  1.00 66.50  ? 392  LYS D N   1 
ATOM   10854 C CA  . LYS D 1 317 ? -65.706 23.450  51.461  1.00 73.74  ? 392  LYS D CA  1 
ATOM   10855 C C   . LYS D 1 317 ? -66.198 24.471  52.483  1.00 69.38  ? 392  LYS D C   1 
ATOM   10856 O O   . LYS D 1 317 ? -67.403 24.575  52.761  1.00 63.49  ? 392  LYS D O   1 
ATOM   10857 C CB  . LYS D 1 317 ? -65.073 22.254  52.175  1.00 64.23  ? 392  LYS D CB  1 
ATOM   10858 C CG  . LYS D 1 317 ? -64.708 21.080  51.280  1.00 54.44  ? 392  LYS D CG  1 
ATOM   10859 C CD  . LYS D 1 317 ? -65.923 20.380  50.709  1.00 75.14  ? 392  LYS D CD  1 
ATOM   10860 C CE  . LYS D 1 317 ? -65.524 19.067  50.057  1.00 81.93  ? 392  LYS D CE  1 
ATOM   10861 N NZ  . LYS D 1 317 ? -64.727 18.214  50.986  1.00 97.05  ? 392  LYS D NZ  1 
ATOM   10862 N N   . LEU D 1 318 ? -65.264 25.233  53.057  1.00 63.30  ? 393  LEU D N   1 
ATOM   10863 C CA  . LEU D 1 318 ? -65.621 26.264  54.025  1.00 58.84  ? 393  LEU D CA  1 
ATOM   10864 C C   . LEU D 1 318 ? -66.515 27.325  53.398  1.00 64.38  ? 393  LEU D C   1 
ATOM   10865 O O   . LEU D 1 318 ? -67.438 27.833  54.044  1.00 66.11  ? 393  LEU D O   1 
ATOM   10866 C CB  . LEU D 1 318 ? -64.353 26.903  54.587  1.00 49.13  ? 393  LEU D CB  1 
ATOM   10867 C CG  . LEU D 1 318 ? -64.569 27.958  55.670  1.00 51.65  ? 393  LEU D CG  1 
ATOM   10868 C CD1 . LEU D 1 318 ? -65.410 27.383  56.799  1.00 62.80  ? 393  LEU D CD1 1 
ATOM   10869 C CD2 . LEU D 1 318 ? -63.244 28.496  56.185  1.00 48.17  ? 393  LEU D CD2 1 
ATOM   10870 N N   . LEU D 1 319 ? -66.246 27.685  52.142  1.00 65.42  ? 394  LEU D N   1 
ATOM   10871 C CA  . LEU D 1 319 ? -67.089 28.671  51.474  1.00 65.16  ? 394  LEU D CA  1 
ATOM   10872 C C   . LEU D 1 319 ? -68.500 28.137  51.260  1.00 71.89  ? 394  LEU D C   1 
ATOM   10873 O O   . LEU D 1 319 ? -69.476 28.883  51.388  1.00 74.69  ? 394  LEU D O   1 
ATOM   10874 C CB  . LEU D 1 319 ? -66.462 29.095  50.148  1.00 62.77  ? 394  LEU D CB  1 
ATOM   10875 C CG  . LEU D 1 319 ? -65.355 30.143  50.263  1.00 61.32  ? 394  LEU D CG  1 
ATOM   10876 C CD1 . LEU D 1 319 ? -64.985 30.670  48.890  1.00 61.84  ? 394  LEU D CD1 1 
ATOM   10877 C CD2 . LEU D 1 319 ? -65.783 31.280  51.176  1.00 51.67  ? 394  LEU D CD2 1 
ATOM   10878 N N   . THR D 1 320 ? -68.631 26.845  50.942  1.00 71.43  ? 395  THR D N   1 
ATOM   10879 C CA  . THR D 1 320 ? -69.969 26.260  50.843  1.00 73.45  ? 395  THR D CA  1 
ATOM   10880 C C   . THR D 1 320 ? -70.680 26.279  52.191  1.00 84.10  ? 395  THR D C   1 
ATOM   10881 O O   . THR D 1 320 ? -71.896 26.498  52.256  1.00 88.16  ? 395  THR D O   1 
ATOM   10882 C CB  . THR D 1 320 ? -69.913 24.830  50.301  1.00 69.04  ? 395  THR D CB  1 
ATOM   10883 O OG1 . THR D 1 320 ? -69.447 23.940  51.324  1.00 94.51  ? 395  THR D OG1 1 
ATOM   10884 C CG2 . THR D 1 320 ? -69.022 24.737  49.078  1.00 71.47  ? 395  THR D CG2 1 
ATOM   10885 N N   . LEU D 1 321 ? -69.944 26.036  53.278  1.00 77.59  ? 396  LEU D N   1 
ATOM   10886 C CA  . LEU D 1 321 ? -70.546 26.140  54.607  1.00 70.73  ? 396  LEU D CA  1 
ATOM   10887 C C   . LEU D 1 321 ? -71.045 27.559  54.867  1.00 81.31  ? 396  LEU D C   1 
ATOM   10888 O O   . LEU D 1 321 ? -72.188 27.767  55.303  1.00 85.64  ? 396  LEU D O   1 
ATOM   10889 C CB  . LEU D 1 321 ? -69.539 25.721  55.676  1.00 58.53  ? 396  LEU D CB  1 
ATOM   10890 C CG  . LEU D 1 321 ? -69.247 24.228  55.811  1.00 56.12  ? 396  LEU D CG  1 
ATOM   10891 C CD1 . LEU D 1 321 ? -68.067 24.020  56.740  1.00 48.22  ? 396  LEU D CD1 1 
ATOM   10892 C CD2 . LEU D 1 321 ? -70.470 23.491  56.326  1.00 68.63  ? 396  LEU D CD2 1 
ATOM   10893 N N   . VAL D 1 322 ? -70.189 28.549  54.598  1.00 82.03  ? 397  VAL D N   1 
ATOM   10894 C CA  . VAL D 1 322 ? -70.560 29.953  54.759  1.00 77.26  ? 397  VAL D CA  1 
ATOM   10895 C C   . VAL D 1 322 ? -71.787 30.284  53.915  1.00 84.60  ? 397  VAL D C   1 
ATOM   10896 O O   . VAL D 1 322 ? -72.647 31.074  54.323  1.00 90.72  ? 397  VAL D O   1 
ATOM   10897 C CB  . VAL D 1 322 ? -69.361 30.855  54.410  1.00 57.56  ? 397  VAL D CB  1 
ATOM   10898 C CG1 . VAL D 1 322 ? -69.787 32.304  54.292  1.00 57.87  ? 397  VAL D CG1 1 
ATOM   10899 C CG2 . VAL D 1 322 ? -68.262 30.703  55.452  1.00 50.64  ? 397  VAL D CG2 1 
ATOM   10900 N N   . LEU D 1 323 ? -71.892 29.675  52.732  1.00 84.74  ? 398  LEU D N   1 
ATOM   10901 C CA  . LEU D 1 323 ? -73.064 29.876  51.885  1.00 87.83  ? 398  LEU D CA  1 
ATOM   10902 C C   . LEU D 1 323 ? -74.313 29.301  52.537  1.00 99.59  ? 398  LEU D C   1 
ATOM   10903 O O   . LEU D 1 323 ? -75.361 29.954  52.579  1.00 115.86 ? 398  LEU D O   1 
ATOM   10904 C CB  . LEU D 1 323 ? -72.826 29.247  50.510  1.00 76.49  ? 398  LEU D CB  1 
ATOM   10905 C CG  . LEU D 1 323 ? -73.961 29.104  49.486  1.00 88.41  ? 398  LEU D CG  1 
ATOM   10906 C CD1 . LEU D 1 323 ? -73.371 29.133  48.094  1.00 77.96  ? 398  LEU D CD1 1 
ATOM   10907 C CD2 . LEU D 1 323 ? -74.767 27.819  49.667  1.00 102.84 ? 398  LEU D CD2 1 
ATOM   10908 N N   . GLN D 1 324 ? -74.221 28.064  53.033  1.00 91.15  ? 399  GLN D N   1 
ATOM   10909 C CA  . GLN D 1 324 ? -75.343 27.460  53.744  1.00 92.59  ? 399  GLN D CA  1 
ATOM   10910 C C   . GLN D 1 324 ? -75.808 28.348  54.887  1.00 103.19 ? 399  GLN D C   1 
ATOM   10911 O O   . GLN D 1 324 ? -77.010 28.446  55.163  1.00 109.44 ? 399  GLN D O   1 
ATOM   10912 C CB  . GLN D 1 324 ? -74.951 26.084  54.280  1.00 99.38  ? 399  GLN D CB  1 
ATOM   10913 C CG  . GLN D 1 324 ? -75.136 24.945  53.306  1.00 99.66  ? 399  GLN D CG  1 
ATOM   10914 C CD  . GLN D 1 324 ? -74.046 23.908  53.455  1.00 111.08 ? 399  GLN D CD  1 
ATOM   10915 O OE1 . GLN D 1 324 ? -73.557 23.363  52.466  1.00 120.55 ? 399  GLN D OE1 1 
ATOM   10916 N NE2 . GLN D 1 324 ? -73.655 23.631  54.693  1.00 124.19 ? 399  GLN D NE2 1 
ATOM   10917 N N   . SER D 1 325 ? -74.866 29.014  55.557  1.00 102.72 ? 400  SER D N   1 
ATOM   10918 C CA  . SER D 1 325 ? -75.214 29.834  56.715  1.00 100.44 ? 400  SER D CA  1 
ATOM   10919 C C   . SER D 1 325 ? -75.842 31.167  56.303  1.00 104.21 ? 400  SER D C   1 
ATOM   10920 O O   . SER D 1 325 ? -77.017 31.421  56.585  1.00 115.25 ? 400  SER D O   1 
ATOM   10921 C CB  . SER D 1 325 ? -73.975 30.060  57.587  1.00 112.54 ? 400  SER D CB  1 
ATOM   10922 O OG  . SER D 1 325 ? -72.843 30.377  56.804  1.00 125.34 ? 400  SER D OG  1 
ATOM   10923 N N   . SER D 1 326 ? -75.074 32.026  55.623  1.00 103.04 ? 401  SER D N   1 
ATOM   10924 C CA  . SER D 1 326 ? -75.528 33.373  55.283  1.00 107.78 ? 401  SER D CA  1 
ATOM   10925 C C   . SER D 1 326 ? -76.322 33.441  53.983  1.00 122.34 ? 401  SER D C   1 
ATOM   10926 O O   . SER D 1 326 ? -77.318 34.169  53.916  1.00 130.37 ? 401  SER D O   1 
ATOM   10927 C CB  . SER D 1 326 ? -74.336 34.321  55.149  1.00 126.87 ? 401  SER D CB  1 
ATOM   10928 O OG  . SER D 1 326 ? -74.026 34.492  53.775  1.00 126.53 ? 401  SER D OG  1 
ATOM   10929 N N   . GLU D 1 327 ? -75.862 32.738  52.945  1.00 118.89 ? 402  GLU D N   1 
ATOM   10930 C CA  . GLU D 1 327 ? -76.453 32.727  51.609  1.00 128.29 ? 402  GLU D CA  1 
ATOM   10931 C C   . GLU D 1 327 ? -76.170 34.013  50.832  1.00 131.61 ? 402  GLU D C   1 
ATOM   10932 O O   . GLU D 1 327 ? -76.198 34.007  49.595  1.00 133.08 ? 402  GLU D O   1 
ATOM   10933 C CB  . GLU D 1 327 ? -77.966 32.468  51.673  1.00 132.33 ? 402  GLU D CB  1 
ATOM   10934 C CG  . GLU D 1 327 ? -78.580 31.959  50.375  1.00 143.45 ? 402  GLU D CG  1 
ATOM   10935 C CD  . GLU D 1 327 ? -77.752 30.860  49.737  1.00 154.54 ? 402  GLU D CD  1 
ATOM   10936 O OE1 . GLU D 1 327 ? -77.681 29.755  50.315  1.00 153.01 ? 402  GLU D OE1 1 
ATOM   10937 O OE2 . GLU D 1 327 ? -77.183 31.099  48.650  1.00 163.07 ? 402  GLU D OE2 1 
ATOM   10938 N N   . GLU D 1 328 ? -75.874 35.118  51.521  1.00 127.55 ? 403  GLU D N   1 
ATOM   10939 C CA  . GLU D 1 328 ? -75.681 36.391  50.840  1.00 120.11 ? 403  GLU D CA  1 
ATOM   10940 C C   . GLU D 1 328 ? -74.334 37.057  51.078  1.00 105.18 ? 403  GLU D C   1 
ATOM   10941 O O   . GLU D 1 328 ? -73.990 37.976  50.322  1.00 111.98 ? 403  GLU D O   1 
ATOM   10942 C CB  . GLU D 1 328 ? -76.785 37.386  51.232  1.00 101.80 ? 403  GLU D CB  1 
ATOM   10943 C CG  . GLU D 1 328 ? -77.918 37.495  50.217  1.00 128.10 ? 403  GLU D CG  1 
ATOM   10944 C CD  . GLU D 1 328 ? -77.424 37.819  48.809  1.00 134.77 ? 403  GLU D CD  1 
ATOM   10945 O OE1 . GLU D 1 328 ? -77.819 37.121  47.850  1.00 133.80 ? 403  GLU D OE1 1 
ATOM   10946 O OE2 . GLU D 1 328 ? -76.638 38.780  48.661  1.00 128.92 ? 403  GLU D OE2 1 
ATOM   10947 N N   . VAL D 1 329 ? -73.559 36.626  52.080  1.00 91.72  ? 404  VAL D N   1 
ATOM   10948 C CA  . VAL D 1 329 ? -72.358 37.373  52.443  1.00 93.09  ? 404  VAL D CA  1 
ATOM   10949 C C   . VAL D 1 329 ? -71.270 37.197  51.395  1.00 109.08 ? 404  VAL D C   1 
ATOM   10950 O O   . VAL D 1 329 ? -70.378 38.043  51.278  1.00 119.38 ? 404  VAL D O   1 
ATOM   10951 C CB  . VAL D 1 329 ? -71.804 36.949  53.821  1.00 99.16  ? 404  VAL D CB  1 
ATOM   10952 C CG1 . VAL D 1 329 ? -71.204 35.566  53.761  1.00 103.82 ? 404  VAL D CG1 1 
ATOM   10953 C CG2 . VAL D 1 329 ? -70.792 37.950  54.329  1.00 108.75 ? 404  VAL D CG2 1 
ATOM   10954 N N   . LEU D 1 330 ? -71.332 36.120  50.611  1.00 105.25 ? 405  LEU D N   1 
ATOM   10955 C CA  . LEU D 1 330 ? -70.236 35.774  49.722  1.00 112.64 ? 405  LEU D CA  1 
ATOM   10956 C C   . LEU D 1 330 ? -70.053 36.761  48.578  1.00 116.46 ? 405  LEU D C   1 
ATOM   10957 O O   . LEU D 1 330 ? -68.952 36.828  48.028  1.00 116.26 ? 405  LEU D O   1 
ATOM   10958 C CB  . LEU D 1 330 ? -70.470 34.387  49.133  1.00 112.15 ? 405  LEU D CB  1 
ATOM   10959 C CG  . LEU D 1 330 ? -70.441 33.210  50.096  1.00 114.51 ? 405  LEU D CG  1 
ATOM   10960 C CD1 . LEU D 1 330 ? -71.531 32.295  49.604  1.00 130.20 ? 405  LEU D CD1 1 
ATOM   10961 C CD2 . LEU D 1 330 ? -69.119 32.485  50.181  1.00 105.06 ? 405  LEU D CD2 1 
ATOM   10962 N N   . THR D 1 331 ? -71.101 37.501  48.197  1.00 95.20  ? 406  THR D N   1 
ATOM   10963 C CA  . THR D 1 331 ? -71.177 38.371  47.014  1.00 97.40  ? 406  THR D CA  1 
ATOM   10964 C C   . THR D 1 331 ? -70.906 37.633  45.706  1.00 108.00 ? 406  THR D C   1 
ATOM   10965 O O   . THR D 1 331 ? -70.278 36.573  45.690  1.00 115.70 ? 406  THR D O   1 
ATOM   10966 C CB  . THR D 1 331 ? -70.242 39.600  47.111  1.00 101.08 ? 406  THR D CB  1 
ATOM   10967 O OG1 . THR D 1 331 ? -70.625 40.524  46.086  1.00 118.62 ? 406  THR D OG1 1 
ATOM   10968 C CG2 . THR D 1 331 ? -68.784 39.244  46.844  1.00 101.31 ? 406  THR D CG2 1 
ATOM   10969 N N   . ALA D 1 332 ? -71.366 38.222  44.600  1.00 95.69  ? 407  ALA D N   1 
ATOM   10970 C CA  . ALA D 1 332 ? -71.361 37.528  43.315  1.00 98.38  ? 407  ALA D CA  1 
ATOM   10971 C C   . ALA D 1 332 ? -69.949 37.351  42.762  1.00 106.66 ? 407  ALA D C   1 
ATOM   10972 O O   . ALA D 1 332 ? -69.658 36.348  42.095  1.00 115.67 ? 407  ALA D O   1 
ATOM   10973 C CB  . ALA D 1 332 ? -72.236 38.279  42.313  1.00 105.35 ? 407  ALA D CB  1 
ATOM   10974 N N   . GLU D 1 333 ? -69.058 38.310  43.019  1.00 103.84 ? 408  GLU D N   1 
ATOM   10975 C CA  . GLU D 1 333 ? -67.698 38.215  42.494  1.00 111.30 ? 408  GLU D CA  1 
ATOM   10976 C C   . GLU D 1 333 ? -66.981 36.986  43.045  1.00 111.19 ? 408  GLU D C   1 
ATOM   10977 O O   . GLU D 1 333 ? -66.362 36.214  42.296  1.00 123.20 ? 408  GLU D O   1 
ATOM   10978 C CB  . GLU D 1 333 ? -66.923 39.492  42.830  1.00 115.08 ? 408  GLU D CB  1 
ATOM   10979 C CG  . GLU D 1 333 ? -67.169 40.662  41.878  1.00 131.39 ? 408  GLU D CG  1 
ATOM   10980 C CD  . GLU D 1 333 ? -68.525 41.325  42.084  1.00 143.77 ? 408  GLU D CD  1 
ATOM   10981 O OE1 . GLU D 1 333 ? -69.103 41.186  43.184  1.00 134.47 ? 408  GLU D OE1 1 
ATOM   10982 O OE2 . GLU D 1 333 ? -69.002 42.004  41.148  1.00 125.35 ? 408  GLU D OE2 1 
ATOM   10983 N N   . ASP D 1 334 ? -67.059 36.789  44.362  1.00 94.41  ? 409  ASP D N   1 
ATOM   10984 C CA  . ASP D 1 334 ? -66.407 35.645  44.987  1.00 100.03 ? 409  ASP D CA  1 
ATOM   10985 C C   . ASP D 1 334 ? -67.026 34.342  44.498  1.00 97.41  ? 409  ASP D C   1 
ATOM   10986 O O   . ASP D 1 334 ? -66.318 33.352  44.256  1.00 104.87 ? 409  ASP D O   1 
ATOM   10987 C CB  . ASP D 1 334 ? -66.526 35.759  46.505  1.00 96.18  ? 409  ASP D CB  1 
ATOM   10988 C CG  . ASP D 1 334 ? -66.014 37.093  47.032  1.00 110.29 ? 409  ASP D CG  1 
ATOM   10989 O OD1 . ASP D 1 334 ? -65.717 37.987  46.210  1.00 128.88 ? 409  ASP D OD1 1 
ATOM   10990 O OD2 . ASP D 1 334 ? -65.921 37.253  48.267  1.00 102.04 ? 409  ASP D OD2 1 
ATOM   10991 N N   . CYS D 1 335 ? -68.355 34.328  44.355  1.00 88.23  ? 410  CYS D N   1 
ATOM   10992 C CA  . CYS D 1 335 ? -69.037 33.172  43.786  1.00 90.68  ? 410  CYS D CA  1 
ATOM   10993 C C   . CYS D 1 335 ? -68.498 32.841  42.403  1.00 98.83  ? 410  CYS D C   1 
ATOM   10994 O O   . CYS D 1 335 ? -68.285 31.670  42.087  1.00 95.72  ? 410  CYS D O   1 
ATOM   10995 C CB  . CYS D 1 335 ? -70.543 33.423  43.725  1.00 81.16  ? 410  CYS D CB  1 
ATOM   10996 S SG  . CYS D 1 335 ? -71.356 33.524  45.336  1.00 111.64 ? 410  CYS D SG  1 
ATOM   10997 N N   . GLU D 1 336 ? -68.259 33.858  41.571  1.00 101.33 ? 411  GLU D N   1 
ATOM   10998 C CA  . GLU D 1 336 ? -67.700 33.615  40.242  1.00 94.99  ? 411  GLU D CA  1 
ATOM   10999 C C   . GLU D 1 336 ? -66.295 33.029  40.336  1.00 90.50  ? 411  GLU D C   1 
ATOM   11000 O O   . GLU D 1 336 ? -65.922 32.137  39.554  1.00 105.67 ? 411  GLU D O   1 
ATOM   11001 C CB  . GLU D 1 336 ? -67.686 34.921  39.447  1.00 109.06 ? 411  GLU D CB  1 
ATOM   11002 C CG  . GLU D 1 336 ? -67.520 34.767  37.945  1.00 138.03 ? 411  GLU D CG  1 
ATOM   11003 C CD  . GLU D 1 336 ? -68.431 33.705  37.368  1.00 155.09 ? 411  GLU D CD  1 
ATOM   11004 O OE1 . GLU D 1 336 ? -69.657 33.935  37.337  1.00 142.47 ? 411  GLU D OE1 1 
ATOM   11005 O OE2 . GLU D 1 336 ? -67.927 32.647  36.932  1.00 167.98 ? 411  GLU D OE2 1 
ATOM   11006 N N   . ASN D 1 337 ? -65.497 33.542  41.279  1.00 95.10  ? 412  ASN D N   1 
ATOM   11007 C CA  . ASN D 1 337 ? -64.172 32.975  41.521  1.00 94.29  ? 412  ASN D CA  1 
ATOM   11008 C C   . ASN D 1 337 ? -64.258 31.483  41.814  1.00 85.69  ? 412  ASN D C   1 
ATOM   11009 O O   . ASN D 1 337 ? -63.490 30.685  41.265  1.00 88.76  ? 412  ASN D O   1 
ATOM   11010 C CB  . ASN D 1 337 ? -63.474 33.700  42.674  1.00 79.53  ? 412  ASN D CB  1 
ATOM   11011 C CG  . ASN D 1 337 ? -63.392 35.195  42.464  1.00 95.58  ? 412  ASN D CG  1 
ATOM   11012 O OD1 . ASN D 1 337 ? -63.447 35.968  43.418  1.00 91.96  ? 412  ASN D OD1 1 
ATOM   11013 N ND2 . ASN D 1 337 ? -63.236 35.612  41.210  1.00 91.98  ? 412  ASN D ND2 1 
ATOM   11014 N N   . VAL D 1 338 ? -65.194 31.086  42.680  1.00 78.16  ? 413  VAL D N   1 
ATOM   11015 C CA  . VAL D 1 338 ? -65.340 29.661  42.981  1.00 70.44  ? 413  VAL D CA  1 
ATOM   11016 C C   . VAL D 1 338 ? -65.899 28.902  41.778  1.00 75.55  ? 413  VAL D C   1 
ATOM   11017 O O   . VAL D 1 338 ? -65.531 27.745  41.538  1.00 73.95  ? 413  VAL D O   1 
ATOM   11018 C CB  . VAL D 1 338 ? -66.202 29.442  44.238  1.00 69.98  ? 413  VAL D CB  1 
ATOM   11019 C CG1 . VAL D 1 338 ? -65.937 28.065  44.810  1.00 58.11  ? 413  VAL D CG1 1 
ATOM   11020 C CG2 . VAL D 1 338 ? -65.892 30.486  45.289  1.00 80.32  ? 413  VAL D CG2 1 
ATOM   11021 N N   . TYR D 1 339 ? -66.792 29.532  41.006  1.00 69.74  ? 414  TYR D N   1 
ATOM   11022 C CA  . TYR D 1 339 ? -67.348 28.884  39.818  1.00 73.64  ? 414  TYR D CA  1 
ATOM   11023 C C   . TYR D 1 339 ? -66.248 28.451  38.863  1.00 76.65  ? 414  TYR D C   1 
ATOM   11024 O O   . TYR D 1 339 ? -66.286 27.342  38.321  1.00 70.12  ? 414  TYR D O   1 
ATOM   11025 C CB  . TYR D 1 339 ? -68.300 29.820  39.073  1.00 94.43  ? 414  TYR D CB  1 
ATOM   11026 C CG  . TYR D 1 339 ? -69.544 30.248  39.806  1.00 87.29  ? 414  TYR D CG  1 
ATOM   11027 C CD1 . TYR D 1 339 ? -70.016 29.549  40.910  1.00 80.16  ? 414  TYR D CD1 1 
ATOM   11028 C CD2 . TYR D 1 339 ? -70.259 31.356  39.377  1.00 86.26  ? 414  TYR D CD2 1 
ATOM   11029 C CE1 . TYR D 1 339 ? -71.159 29.959  41.571  1.00 76.89  ? 414  TYR D CE1 1 
ATOM   11030 C CE2 . TYR D 1 339 ? -71.394 31.769  40.024  1.00 96.19  ? 414  TYR D CE2 1 
ATOM   11031 C CZ  . TYR D 1 339 ? -71.843 31.070  41.117  1.00 86.71  ? 414  TYR D CZ  1 
ATOM   11032 O OH  . TYR D 1 339 ? -72.982 31.502  41.746  1.00 85.18  ? 414  TYR D OH  1 
ATOM   11033 N N   . HIS D 1 340 ? -65.271 29.330  38.627  1.00 85.20  ? 415  HIS D N   1 
ATOM   11034 C CA  . HIS D 1 340 ? -64.227 29.021  37.653  1.00 84.48  ? 415  HIS D CA  1 
ATOM   11035 C C   . HIS D 1 340 ? -63.455 27.752  38.000  1.00 80.35  ? 415  HIS D C   1 
ATOM   11036 O O   . HIS D 1 340 ? -62.878 27.127  37.102  1.00 83.88  ? 415  HIS D O   1 
ATOM   11037 C CB  . HIS D 1 340 ? -63.259 30.195  37.520  1.00 83.32  ? 415  HIS D CB  1 
ATOM   11038 C CG  . HIS D 1 340 ? -63.907 31.461  37.054  1.00 90.47  ? 415  HIS D CG  1 
ATOM   11039 N ND1 . HIS D 1 340 ? -63.658 32.682  37.640  1.00 102.71 ? 415  HIS D ND1 1 
ATOM   11040 C CD2 . HIS D 1 340 ? -64.797 31.694  36.061  1.00 91.80  ? 415  HIS D CD2 1 
ATOM   11041 C CE1 . HIS D 1 340 ? -64.365 33.614  37.027  1.00 111.26 ? 415  HIS D CE1 1 
ATOM   11042 N NE2 . HIS D 1 340 ? -65.065 33.041  36.065  1.00 104.26 ? 415  HIS D NE2 1 
ATOM   11043 N N   . LEU D 1 341 ? -63.445 27.348  39.272  1.00 69.13  ? 416  LEU D N   1 
ATOM   11044 C CA  . LEU D 1 341 ? -62.681 26.181  39.696  1.00 68.80  ? 416  LEU D CA  1 
ATOM   11045 C C   . LEU D 1 341 ? -63.298 24.860  39.250  1.00 72.71  ? 416  LEU D C   1 
ATOM   11046 O O   . LEU D 1 341 ? -62.622 23.831  39.332  1.00 72.48  ? 416  LEU D O   1 
ATOM   11047 C CB  . LEU D 1 341 ? -62.528 26.191  41.216  1.00 65.81  ? 416  LEU D CB  1 
ATOM   11048 C CG  . LEU D 1 341 ? -61.914 27.466  41.795  1.00 65.82  ? 416  LEU D CG  1 
ATOM   11049 C CD1 . LEU D 1 341 ? -61.793 27.359  43.306  1.00 70.88  ? 416  LEU D CD1 1 
ATOM   11050 C CD2 . LEU D 1 341 ? -60.568 27.775  41.154  1.00 58.81  ? 416  LEU D CD2 1 
ATOM   11051 N N   . VAL D 1 342 ? -64.551 24.851  38.787  1.00 75.03  ? 417  VAL D N   1 
ATOM   11052 C CA  . VAL D 1 342 ? -65.131 23.610  38.287  1.00 72.98  ? 417  VAL D CA  1 
ATOM   11053 C C   . VAL D 1 342 ? -64.436 23.147  37.015  1.00 78.30  ? 417  VAL D C   1 
ATOM   11054 O O   . VAL D 1 342 ? -64.528 21.966  36.657  1.00 80.77  ? 417  VAL D O   1 
ATOM   11055 C CB  . VAL D 1 342 ? -66.644 23.754  38.036  1.00 66.23  ? 417  VAL D CB  1 
ATOM   11056 C CG1 . VAL D 1 342 ? -67.332 24.351  39.250  1.00 67.69  ? 417  VAL D CG1 1 
ATOM   11057 C CG2 . VAL D 1 342 ? -66.904 24.598  36.797  1.00 75.58  ? 417  VAL D CG2 1 
ATOM   11058 N N   . TYR D 1 343 ? -63.743 24.047  36.321  1.00 69.69  ? 418  TYR D N   1 
ATOM   11059 C CA  . TYR D 1 343 ? -62.961 23.704  35.145  1.00 70.04  ? 418  TYR D CA  1 
ATOM   11060 C C   . TYR D 1 343 ? -61.504 23.413  35.479  1.00 72.16  ? 418  TYR D C   1 
ATOM   11061 O O   . TYR D 1 343 ? -60.682 23.304  34.565  1.00 72.25  ? 418  TYR D O   1 
ATOM   11062 C CB  . TYR D 1 343 ? -63.041 24.829  34.111  1.00 72.84  ? 418  TYR D CB  1 
ATOM   11063 C CG  . TYR D 1 343 ? -64.451 25.198  33.706  1.00 72.77  ? 418  TYR D CG  1 
ATOM   11064 C CD1 . TYR D 1 343 ? -65.294 24.263  33.117  1.00 73.26  ? 418  TYR D CD1 1 
ATOM   11065 C CD2 . TYR D 1 343 ? -64.938 26.481  33.913  1.00 76.03  ? 418  TYR D CD2 1 
ATOM   11066 C CE1 . TYR D 1 343 ? -66.582 24.598  32.744  1.00 71.77  ? 418  TYR D CE1 1 
ATOM   11067 C CE2 . TYR D 1 343 ? -66.222 26.825  33.545  1.00 88.70  ? 418  TYR D CE2 1 
ATOM   11068 C CZ  . TYR D 1 343 ? -67.041 25.881  32.961  1.00 84.05  ? 418  TYR D CZ  1 
ATOM   11069 O OH  . TYR D 1 343 ? -68.322 26.224  32.595  1.00 92.97  ? 418  TYR D OH  1 
ATOM   11070 N N   . SER D 1 344 ? -61.167 23.294  36.761  1.00 70.64  ? 419  SER D N   1 
ATOM   11071 C CA  . SER D 1 344 ? -59.796 23.000  37.151  1.00 72.13  ? 419  SER D CA  1 
ATOM   11072 C C   . SER D 1 344 ? -59.462 21.537  36.878  1.00 79.63  ? 419  SER D C   1 
ATOM   11073 O O   . SER D 1 344 ? -60.325 20.656  36.940  1.00 75.62  ? 419  SER D O   1 
ATOM   11074 C CB  . SER D 1 344 ? -59.580 23.317  38.632  1.00 67.62  ? 419  SER D CB  1 
ATOM   11075 O OG  . SER D 1 344 ? -58.374 22.746  39.105  1.00 80.27  ? 419  SER D OG  1 
ATOM   11076 N N   . ALA D 1 345 ? -58.186 21.286  36.571  1.00 75.55  ? 420  ALA D N   1 
ATOM   11077 C CA  . ALA D 1 345 ? -57.746 19.921  36.310  1.00 73.04  ? 420  ALA D CA  1 
ATOM   11078 C C   . ALA D 1 345 ? -57.825 19.055  37.560  1.00 71.66  ? 420  ALA D C   1 
ATOM   11079 O O   . ALA D 1 345 ? -58.063 17.846  37.459  1.00 74.50  ? 420  ALA D O   1 
ATOM   11080 C CB  . ALA D 1 345 ? -56.322 19.921  35.756  1.00 72.83  ? 420  ALA D CB  1 
ATOM   11081 N N   . HIS D 1 346 ? -57.633 19.649  38.736  1.00 72.22  ? 421  HIS D N   1 
ATOM   11082 C CA  . HIS D 1 346 ? -57.700 18.913  39.994  1.00 71.91  ? 421  HIS D CA  1 
ATOM   11083 C C   . HIS D 1 346 ? -59.152 18.579  40.311  1.00 66.50  ? 421  HIS D C   1 
ATOM   11084 O O   . HIS D 1 346 ? -59.941 19.468  40.647  1.00 72.70  ? 421  HIS D O   1 
ATOM   11085 C CB  . HIS D 1 346 ? -57.072 19.736  41.114  1.00 70.37  ? 421  HIS D CB  1 
ATOM   11086 C CG  . HIS D 1 346 ? -56.725 18.934  42.329  1.00 68.02  ? 421  HIS D CG  1 
ATOM   11087 N ND1 . HIS D 1 346 ? -55.792 17.920  42.309  1.00 67.89  ? 421  HIS D ND1 1 
ATOM   11088 C CD2 . HIS D 1 346 ? -57.191 18.993  43.599  1.00 76.64  ? 421  HIS D CD2 1 
ATOM   11089 C CE1 . HIS D 1 346 ? -55.694 17.391  43.515  1.00 71.80  ? 421  HIS D CE1 1 
ATOM   11090 N NE2 . HIS D 1 346 ? -56.533 18.024  44.316  1.00 67.47  ? 421  HIS D NE2 1 
ATOM   11091 N N   . ARG D 1 347 ? -59.505 17.295  40.212  1.00 62.22  ? 422  ARG D N   1 
ATOM   11092 C CA  . ARG D 1 347 ? -60.898 16.899  40.409  1.00 65.83  ? 422  ARG D CA  1 
ATOM   11093 C C   . ARG D 1 347 ? -61.418 17.144  41.821  1.00 69.94  ? 422  ARG D C   1 
ATOM   11094 O O   . ARG D 1 347 ? -62.616 17.444  41.953  1.00 69.23  ? 422  ARG D O   1 
ATOM   11095 C CB  . ARG D 1 347 ? -61.103 15.429  40.023  1.00 71.03  ? 422  ARG D CB  1 
ATOM   11096 C CG  . ARG D 1 347 ? -62.581 15.079  39.865  1.00 60.53  ? 422  ARG D CG  1 
ATOM   11097 C CD  . ARG D 1 347 ? -62.825 13.602  39.634  1.00 61.70  ? 422  ARG D CD  1 
ATOM   11098 N NE  . ARG D 1 347 ? -64.205 13.359  39.230  1.00 62.19  ? 422  ARG D NE  1 
ATOM   11099 C CZ  . ARG D 1 347 ? -65.202 13.125  40.073  1.00 72.73  ? 422  ARG D CZ  1 
ATOM   11100 N NH1 . ARG D 1 347 ? -65.002 13.061  41.378  1.00 65.64  ? 422  ARG D NH1 1 
ATOM   11101 N NH2 . ARG D 1 347 ? -66.431 12.956  39.593  1.00 70.42  ? 422  ARG D NH2 1 
ATOM   11102 N N   . PRO D 1 348 ? -60.632 17.010  42.898  1.00 72.19  ? 423  PRO D N   1 
ATOM   11103 C CA  . PRO D 1 348 ? -61.165 17.416  44.216  1.00 72.06  ? 423  PRO D CA  1 
ATOM   11104 C C   . PRO D 1 348 ? -61.600 18.872  44.257  1.00 66.81  ? 423  PRO D C   1 
ATOM   11105 O O   . PRO D 1 348 ? -62.725 19.181  44.689  1.00 71.04  ? 423  PRO D O   1 
ATOM   11106 C CB  . PRO D 1 348 ? -59.990 17.129  45.157  1.00 68.11  ? 423  PRO D CB  1 
ATOM   11107 C CG  . PRO D 1 348 ? -59.295 15.983  44.519  1.00 66.97  ? 423  PRO D CG  1 
ATOM   11108 C CD  . PRO D 1 348 ? -59.370 16.257  43.040  1.00 63.57  ? 423  PRO D CD  1 
ATOM   11109 N N   . VAL D 1 349 ? -60.725 19.781  43.816  1.00 54.95  ? 424  VAL D N   1 
ATOM   11110 C CA  . VAL D 1 349 ? -61.083 21.193  43.722  1.00 60.74  ? 424  VAL D CA  1 
ATOM   11111 C C   . VAL D 1 349 ? -62.327 21.370  42.861  1.00 61.96  ? 424  VAL D C   1 
ATOM   11112 O O   . VAL D 1 349 ? -63.245 22.126  43.212  1.00 73.01  ? 424  VAL D O   1 
ATOM   11113 C CB  . VAL D 1 349 ? -59.893 22.006  43.174  1.00 59.26  ? 424  VAL D CB  1 
ATOM   11114 C CG1 . VAL D 1 349 ? -60.368 23.302  42.533  1.00 62.12  ? 424  VAL D CG1 1 
ATOM   11115 C CG2 . VAL D 1 349 ? -58.889 22.290  44.276  1.00 59.42  ? 424  VAL D CG2 1 
ATOM   11116 N N   . ALA D 1 350 ? -62.386 20.656  41.735  1.00 52.18  ? 425  ALA D N   1 
ATOM   11117 C CA  . ALA D 1 350 ? -63.480 20.842  40.789  1.00 50.12  ? 425  ALA D CA  1 
ATOM   11118 C C   . ALA D 1 350 ? -64.807 20.374  41.370  1.00 68.30  ? 425  ALA D C   1 
ATOM   11119 O O   . ALA D 1 350 ? -65.833 21.034  41.185  1.00 80.09  ? 425  ALA D O   1 
ATOM   11120 C CB  . ALA D 1 350 ? -63.176 20.109  39.483  1.00 65.34  ? 425  ALA D CB  1 
ATOM   11121 N N   . VAL D 1 351 ? -64.812 19.250  42.089  1.00 63.83  ? 426  VAL D N   1 
ATOM   11122 C CA  . VAL D 1 351 ? -66.070 18.748  42.635  1.00 60.27  ? 426  VAL D CA  1 
ATOM   11123 C C   . VAL D 1 351 ? -66.506 19.580  43.834  1.00 65.78  ? 426  VAL D C   1 
ATOM   11124 O O   . VAL D 1 351 ? -67.707 19.775  44.053  1.00 68.36  ? 426  VAL D O   1 
ATOM   11125 C CB  . VAL D 1 351 ? -65.968 17.250  42.988  1.00 58.51  ? 426  VAL D CB  1 
ATOM   11126 C CG1 . VAL D 1 351 ? -65.752 16.417  41.729  1.00 57.61  ? 426  VAL D CG1 1 
ATOM   11127 C CG2 . VAL D 1 351 ? -64.883 16.990  44.027  1.00 61.51  ? 426  VAL D CG2 1 
ATOM   11128 N N   . ALA D 1 352 ? -65.557 20.105  44.617  1.00 70.61  ? 427  ALA D N   1 
ATOM   11129 C CA  . ALA D 1 352 ? -65.939 21.023  45.686  1.00 69.41  ? 427  ALA D CA  1 
ATOM   11130 C C   . ALA D 1 352 ? -66.566 22.292  45.116  1.00 75.25  ? 427  ALA D C   1 
ATOM   11131 O O   . ALA D 1 352 ? -67.626 22.742  45.581  1.00 85.17  ? 427  ALA D O   1 
ATOM   11132 C CB  . ALA D 1 352 ? -64.726 21.352  46.557  1.00 63.84  ? 427  ALA D CB  1 
ATOM   11133 N N   . ALA D 1 353 ? -65.935 22.873  44.089  1.00 65.56  ? 428  ALA D N   1 
ATOM   11134 C CA  . ALA D 1 353 ? -66.504 24.041  43.427  1.00 64.23  ? 428  ALA D CA  1 
ATOM   11135 C C   . ALA D 1 353 ? -67.834 23.724  42.759  1.00 62.77  ? 428  ALA D C   1 
ATOM   11136 O O   . ALA D 1 353 ? -68.712 24.587  42.697  1.00 73.64  ? 428  ALA D O   1 
ATOM   11137 C CB  . ALA D 1 353 ? -65.516 24.588  42.401  1.00 58.95  ? 428  ALA D CB  1 
ATOM   11138 N N   . GLY D 1 354 ? -68.008 22.499  42.262  1.00 63.61  ? 429  GLY D N   1 
ATOM   11139 C CA  . GLY D 1 354 ? -69.279 22.130  41.668  1.00 73.67  ? 429  GLY D CA  1 
ATOM   11140 C C   . GLY D 1 354 ? -70.374 21.999  42.705  1.00 74.98  ? 429  GLY D C   1 
ATOM   11141 O O   . GLY D 1 354 ? -71.526 22.345  42.446  1.00 75.47  ? 429  GLY D O   1 
ATOM   11142 N N   . GLU D 1 355 ? -70.032 21.491  43.891  1.00 75.80  ? 430  GLU D N   1 
ATOM   11143 C CA  . GLU D 1 355 ? -70.982 21.503  44.998  1.00 69.87  ? 430  GLU D CA  1 
ATOM   11144 C C   . GLU D 1 355 ? -71.376 22.930  45.353  1.00 78.74  ? 430  GLU D C   1 
ATOM   11145 O O   . GLU D 1 355 ? -72.556 23.220  45.585  1.00 85.16  ? 430  GLU D O   1 
ATOM   11146 C CB  . GLU D 1 355 ? -70.386 20.807  46.221  1.00 78.80  ? 430  GLU D CB  1 
ATOM   11147 C CG  . GLU D 1 355 ? -70.272 19.303  46.111  1.00 92.34  ? 430  GLU D CG  1 
ATOM   11148 C CD  . GLU D 1 355 ? -69.142 18.756  46.958  1.00 102.10 ? 430  GLU D CD  1 
ATOM   11149 O OE1 . GLU D 1 355 ? -69.019 19.189  48.125  1.00 89.23  ? 430  GLU D OE1 1 
ATOM   11150 O OE2 . GLU D 1 355 ? -68.380 17.897  46.464  1.00 99.14  ? 430  GLU D OE2 1 
ATOM   11151 N N   . PHE D 1 356 ? -70.392 23.832  45.407  1.00 68.31  ? 431  PHE D N   1 
ATOM   11152 C CA  . PHE D 1 356 ? -70.684 25.234  45.700  1.00 70.43  ? 431  PHE D CA  1 
ATOM   11153 C C   . PHE D 1 356 ? -71.614 25.829  44.646  1.00 71.05  ? 431  PHE D C   1 
ATOM   11154 O O   . PHE D 1 356 ? -72.596 26.507  44.973  1.00 74.79  ? 431  PHE D O   1 
ATOM   11155 C CB  . PHE D 1 356 ? -69.379 26.029  45.793  1.00 72.77  ? 431  PHE D CB  1 
ATOM   11156 C CG  . PHE D 1 356 ? -69.570 27.488  46.110  1.00 72.97  ? 431  PHE D CG  1 
ATOM   11157 C CD1 . PHE D 1 356 ? -69.803 28.409  45.100  1.00 66.81  ? 431  PHE D CD1 1 
ATOM   11158 C CD2 . PHE D 1 356 ? -69.510 27.938  47.419  1.00 69.06  ? 431  PHE D CD2 1 
ATOM   11159 C CE1 . PHE D 1 356 ? -69.979 29.747  45.390  1.00 71.40  ? 431  PHE D CE1 1 
ATOM   11160 C CE2 . PHE D 1 356 ? -69.683 29.277  47.716  1.00 82.32  ? 431  PHE D CE2 1 
ATOM   11161 C CZ  . PHE D 1 356 ? -69.918 30.183  46.699  1.00 80.64  ? 431  PHE D CZ  1 
ATOM   11162 N N   . LEU D 1 357 ? -71.315 25.578  43.370  1.00 68.10  ? 432  LEU D N   1 
ATOM   11163 C CA  . LEU D 1 357 ? -72.147 26.075  42.279  1.00 69.82  ? 432  LEU D CA  1 
ATOM   11164 C C   . LEU D 1 357 ? -73.554 25.490  42.339  1.00 80.56  ? 432  LEU D C   1 
ATOM   11165 O O   . LEU D 1 357 ? -74.540 26.192  42.086  1.00 84.06  ? 432  LEU D O   1 
ATOM   11166 C CB  . LEU D 1 357 ? -71.479 25.743  40.944  1.00 65.10  ? 432  LEU D CB  1 
ATOM   11167 C CG  . LEU D 1 357 ? -72.222 26.000  39.633  1.00 74.24  ? 432  LEU D CG  1 
ATOM   11168 C CD1 . LEU D 1 357 ? -72.353 27.486  39.347  1.00 73.18  ? 432  LEU D CD1 1 
ATOM   11169 C CD2 . LEU D 1 357 ? -71.503 25.295  38.496  1.00 77.58  ? 432  LEU D CD2 1 
ATOM   11170 N N   . TYR D 1 358 ? -73.661 24.202  42.668  1.00 79.47  ? 433  TYR D N   1 
ATOM   11171 C CA  . TYR D 1 358 ? -74.957 23.539  42.750  1.00 78.31  ? 433  TYR D CA  1 
ATOM   11172 C C   . TYR D 1 358 ? -75.801 24.137  43.867  1.00 87.19  ? 433  TYR D C   1 
ATOM   11173 O O   . TYR D 1 358 ? -76.994 24.408  43.687  1.00 93.39  ? 433  TYR D O   1 
ATOM   11174 C CB  . TYR D 1 358 ? -74.737 22.037  42.957  1.00 76.74  ? 433  TYR D CB  1 
ATOM   11175 C CG  . TYR D 1 358 ? -75.949 21.237  43.383  1.00 87.75  ? 433  TYR D CG  1 
ATOM   11176 C CD1 . TYR D 1 358 ? -76.295 21.117  44.724  1.00 100.27 ? 433  TYR D CD1 1 
ATOM   11177 C CD2 . TYR D 1 358 ? -76.729 20.572  42.445  1.00 90.13  ? 433  TYR D CD2 1 
ATOM   11178 C CE1 . TYR D 1 358 ? -77.397 20.380  45.115  1.00 117.17 ? 433  TYR D CE1 1 
ATOM   11179 C CE2 . TYR D 1 358 ? -77.832 19.829  42.827  1.00 91.97  ? 433  TYR D CE2 1 
ATOM   11180 C CZ  . TYR D 1 358 ? -78.162 19.738  44.164  1.00 109.34 ? 433  TYR D CZ  1 
ATOM   11181 O OH  . TYR D 1 358 ? -79.258 19.002  44.554  1.00 114.90 ? 433  TYR D OH  1 
ATOM   11182 N N   . LYS D 1 359 ? -75.190 24.357  45.033  1.00 80.72  ? 434  LYS D N   1 
ATOM   11183 C CA  . LYS D 1 359 ? -75.920 24.959  46.143  1.00 82.85  ? 434  LYS D CA  1 
ATOM   11184 C C   . LYS D 1 359 ? -76.315 26.398  45.832  1.00 82.13  ? 434  LYS D C   1 
ATOM   11185 O O   . LYS D 1 359 ? -77.410 26.840  46.198  1.00 92.13  ? 434  LYS D O   1 
ATOM   11186 C CB  . LYS D 1 359 ? -75.081 24.899  47.418  1.00 73.58  ? 434  LYS D CB  1 
ATOM   11187 C CG  . LYS D 1 359 ? -74.822 23.494  47.928  1.00 86.67  ? 434  LYS D CG  1 
ATOM   11188 C CD  . LYS D 1 359 ? -75.938 23.026  48.847  1.00 92.63  ? 434  LYS D CD  1 
ATOM   11189 C CE  . LYS D 1 359 ? -75.383 22.277  50.046  1.00 93.67  ? 434  LYS D CE  1 
ATOM   11190 N NZ  . LYS D 1 359 ? -74.364 21.267  49.646  1.00 116.85 ? 434  LYS D NZ  1 
ATOM   11191 N N   . LYS D 1 360 ? -75.439 27.142  45.152  1.00 74.97  ? 435  LYS D N   1 
ATOM   11192 C CA  . LYS D 1 360 ? -75.717 28.549  44.883  1.00 75.49  ? 435  LYS D CA  1 
ATOM   11193 C C   . LYS D 1 360 ? -76.889 28.719  43.923  1.00 86.24  ? 435  LYS D C   1 
ATOM   11194 O O   . LYS D 1 360 ? -77.751 29.579  44.136  1.00 106.84 ? 435  LYS D O   1 
ATOM   11195 C CB  . LYS D 1 360 ? -74.471 29.232  44.326  1.00 71.42  ? 435  LYS D CB  1 
ATOM   11196 C CG  . LYS D 1 360 ? -74.614 30.731  44.143  1.00 81.27  ? 435  LYS D CG  1 
ATOM   11197 C CD  . LYS D 1 360 ? -74.347 31.506  45.418  1.00 92.65  ? 435  LYS D CD  1 
ATOM   11198 C CE  . LYS D 1 360 ? -75.431 32.542  45.656  1.00 98.51  ? 435  LYS D CE  1 
ATOM   11199 N NZ  . LYS D 1 360 ? -75.477 32.981  47.074  1.00 116.25 ? 435  LYS D NZ  1 
ATOM   11200 N N   . LEU D 1 361 ? -76.939 27.917  42.859  1.00 83.57  ? 436  LEU D N   1 
ATOM   11201 C CA  . LEU D 1 361 ? -77.940 28.100  41.812  1.00 78.82  ? 436  LEU D CA  1 
ATOM   11202 C C   . LEU D 1 361 ? -78.820 26.871  41.626  1.00 89.74  ? 436  LEU D C   1 
ATOM   11203 O O   . LEU D 1 361 ? -80.039 26.963  41.803  1.00 100.60 ? 436  LEU D O   1 
ATOM   11204 C CB  . LEU D 1 361 ? -77.252 28.473  40.492  1.00 69.81  ? 436  LEU D CB  1 
ATOM   11205 C CG  . LEU D 1 361 ? -76.113 29.493  40.571  1.00 81.92  ? 436  LEU D CG  1 
ATOM   11206 C CD1 . LEU D 1 361 ? -75.346 29.552  39.256  1.00 93.52  ? 436  LEU D CD1 1 
ATOM   11207 C CD2 . LEU D 1 361 ? -76.634 30.867  40.957  1.00 91.19  ? 436  LEU D CD2 1 
ATOM   11208 N N   . PHE D 1 362 ? -78.243 25.722  41.276  1.00 89.73  ? 437  PHE D N   1 
ATOM   11209 C CA  . PHE D 1 362 ? -79.025 24.555  40.864  1.00 83.39  ? 437  PHE D CA  1 
ATOM   11210 C C   . PHE D 1 362 ? -79.466 23.758  42.093  1.00 91.64  ? 437  PHE D C   1 
ATOM   11211 O O   . PHE D 1 362 ? -78.944 22.688  42.406  1.00 103.70 ? 437  PHE D O   1 
ATOM   11212 C CB  . PHE D 1 362 ? -78.212 23.692  39.907  1.00 78.30  ? 437  PHE D CB  1 
ATOM   11213 C CG  . PHE D 1 362 ? -77.479 24.478  38.863  1.00 76.69  ? 437  PHE D CG  1 
ATOM   11214 C CD1 . PHE D 1 362 ? -78.152 25.021  37.783  1.00 83.51  ? 437  PHE D CD1 1 
ATOM   11215 C CD2 . PHE D 1 362 ? -76.114 24.686  38.971  1.00 83.00  ? 437  PHE D CD2 1 
ATOM   11216 C CE1 . PHE D 1 362 ? -77.475 25.751  36.826  1.00 78.88  ? 437  PHE D CE1 1 
ATOM   11217 C CE2 . PHE D 1 362 ? -75.433 25.414  38.017  1.00 86.92  ? 437  PHE D CE2 1 
ATOM   11218 C CZ  . PHE D 1 362 ? -76.114 25.947  36.943  1.00 90.96  ? 437  PHE D CZ  1 
ATOM   11219 N N   . SER D 1 363 ? -80.459 24.299  42.794  1.00 101.70 ? 438  SER D N   1 
ATOM   11220 C CA  . SER D 1 363 ? -80.967 23.641  43.990  1.00 107.35 ? 438  SER D CA  1 
ATOM   11221 C C   . SER D 1 363 ? -82.419 24.031  44.217  1.00 120.96 ? 438  SER D C   1 
ATOM   11222 O O   . SER D 1 363 ? -82.834 25.149  43.899  1.00 123.19 ? 438  SER D O   1 
ATOM   11223 C CB  . SER D 1 363 ? -80.127 23.992  45.225  1.00 100.18 ? 438  SER D CB  1 
ATOM   11224 O OG  . SER D 1 363 ? -79.642 25.320  45.152  1.00 91.61  ? 438  SER D OG  1 
ATOM   11225 N N   . ARG D 1 364 ? -83.186 23.086  44.769  1.00 133.25 ? 439  ARG D N   1 
ATOM   11226 C CA  . ARG D 1 364 ? -84.595 23.301  45.108  1.00 148.86 ? 439  ARG D CA  1 
ATOM   11227 C C   . ARG D 1 364 ? -85.416 23.685  43.877  1.00 145.42 ? 439  ARG D C   1 
ATOM   11228 O O   . ARG D 1 364 ? -86.378 24.449  43.965  1.00 151.74 ? 439  ARG D O   1 
ATOM   11229 C CB  . ARG D 1 364 ? -84.737 24.349  46.215  1.00 153.32 ? 439  ARG D CB  1 
ATOM   11230 C CG  . ARG D 1 364 ? -86.018 24.252  47.030  1.00 149.29 ? 439  ARG D CG  1 
ATOM   11231 C CD  . ARG D 1 364 ? -86.568 25.641  47.299  1.00 155.50 ? 439  ARG D CD  1 
ATOM   11232 N NE  . ARG D 1 364 ? -86.664 26.431  46.076  1.00 173.02 ? 439  ARG D NE  1 
ATOM   11233 C CZ  . ARG D 1 364 ? -87.785 26.634  45.397  1.00 167.86 ? 439  ARG D CZ  1 
ATOM   11234 N NH1 . ARG D 1 364 ? -88.943 26.153  45.815  1.00 158.24 ? 439  ARG D NH1 1 
ATOM   11235 N NH2 . ARG D 1 364 ? -87.741 27.336  44.268  1.00 174.79 ? 439  ARG D NH2 1 
ATOM   11236 N N   . ARG D 1 365 ? -85.031 23.143  42.723  1.00 142.21 ? 440  ARG D N   1 
ATOM   11237 C CA  . ARG D 1 365 ? -85.704 23.384  41.440  1.00 135.31 ? 440  ARG D CA  1 
ATOM   11238 C C   . ARG D 1 365 ? -86.127 24.828  41.210  1.00 139.61 ? 440  ARG D C   1 
ATOM   11239 O O   . ARG D 1 365 ? -85.284 25.708  41.036  1.00 137.02 ? 440  ARG D O   1 
ATOM   11240 C CB  . ARG D 1 365 ? -86.918 22.466  41.313  1.00 128.29 ? 440  ARG D CB  1 
ATOM   11241 C CG  . ARG D 1 365 ? -86.571 21.047  41.641  1.00 125.51 ? 440  ARG D CG  1 
ATOM   11242 C CD  . ARG D 1 365 ? -87.740 20.102  41.543  1.00 109.70 ? 440  ARG D CD  1 
ATOM   11243 N NE  . ARG D 1 365 ? -87.272 18.877  40.915  1.00 118.02 ? 440  ARG D NE  1 
ATOM   11244 C CZ  . ARG D 1 365 ? -86.225 18.167  41.319  1.00 145.05 ? 440  ARG D CZ  1 
ATOM   11245 N NH1 . ARG D 1 365 ? -85.707 18.309  42.533  1.00 152.80 ? 440  ARG D NH1 1 
ATOM   11246 N NH2 . ARG D 1 365 ? -85.695 17.274  40.492  1.00 145.10 ? 440  ARG D NH2 1 
ATOM   11247 N N   . GLN D 1 379 ? -91.025 20.028  29.149  1.00 105.12 ? 454  GLN D N   1 
ATOM   11248 C CA  . GLN D 1 379 ? -90.632 20.871  30.273  1.00 103.27 ? 454  GLN D CA  1 
ATOM   11249 C C   . GLN D 1 379 ? -91.138 20.333  31.603  1.00 121.85 ? 454  GLN D C   1 
ATOM   11250 O O   . GLN D 1 379 ? -91.917 19.379  31.652  1.00 116.48 ? 454  GLN D O   1 
ATOM   11251 C CB  . GLN D 1 379 ? -91.121 22.307  30.062  1.00 94.85  ? 454  GLN D CB  1 
ATOM   11252 C CG  . GLN D 1 379 ? -90.134 23.175  29.291  1.00 111.29 ? 454  GLN D CG  1 
ATOM   11253 C CD  . GLN D 1 379 ? -90.391 23.192  27.797  1.00 121.90 ? 454  GLN D CD  1 
ATOM   11254 O OE1 . GLN D 1 379 ? -91.045 22.301  27.258  1.00 127.86 ? 454  GLN D OE1 1 
ATOM   11255 N NE2 . GLN D 1 379 ? -89.869 24.206  27.119  1.00 113.07 ? 454  GLN D NE2 1 
ATOM   11256 N N   . GLY D 1 380 ? -90.672 20.952  32.683  1.00 137.51 ? 455  GLY D N   1 
ATOM   11257 C CA  . GLY D 1 380 ? -90.999 20.523  34.019  1.00 122.42 ? 455  GLY D CA  1 
ATOM   11258 C C   . GLY D 1 380 ? -90.237 21.321  35.056  1.00 114.62 ? 455  GLY D C   1 
ATOM   11259 O O   . GLY D 1 380 ? -89.845 22.470  34.824  1.00 105.75 ? 455  GLY D O   1 
ATOM   11260 N N   . PRO D 1 381 ? -90.001 20.720  36.220  1.00 116.65 ? 456  PRO D N   1 
ATOM   11261 C CA  . PRO D 1 381 ? -89.364 21.456  37.323  1.00 119.30 ? 456  PRO D CA  1 
ATOM   11262 C C   . PRO D 1 381 ? -87.898 21.784  37.082  1.00 120.71 ? 456  PRO D C   1 
ATOM   11263 O O   . PRO D 1 381 ? -87.467 22.915  37.330  1.00 124.81 ? 456  PRO D O   1 
ATOM   11264 C CB  . PRO D 1 381 ? -89.527 20.509  38.516  1.00 117.74 ? 456  PRO D CB  1 
ATOM   11265 C CG  . PRO D 1 381 ? -89.708 19.148  37.914  1.00 116.21 ? 456  PRO D CG  1 
ATOM   11266 C CD  . PRO D 1 381 ? -90.401 19.357  36.606  1.00 103.37 ? 456  PRO D CD  1 
ATOM   11267 N N   . ASN D 1 382 ? -87.119 20.810  36.612  1.00 125.68 ? 457  ASN D N   1 
ATOM   11268 C CA  . ASN D 1 382 ? -85.699 21.021  36.354  1.00 112.16 ? 457  ASN D CA  1 
ATOM   11269 C C   . ASN D 1 382 ? -85.429 21.786  35.066  1.00 107.45 ? 457  ASN D C   1 
ATOM   11270 O O   . ASN D 1 382 ? -84.260 22.044  34.758  1.00 113.04 ? 457  ASN D O   1 
ATOM   11271 C CB  . ASN D 1 382 ? -84.964 19.678  36.306  1.00 89.30  ? 457  ASN D CB  1 
ATOM   11272 C CG  . ASN D 1 382 ? -84.801 19.055  37.674  1.00 100.79 ? 457  ASN D CG  1 
ATOM   11273 O OD1 . ASN D 1 382 ? -85.209 19.630  38.685  1.00 126.40 ? 457  ASN D OD1 1 
ATOM   11274 N ND2 . ASN D 1 382 ? -84.198 17.875  37.715  1.00 101.12 ? 457  ASN D ND2 1 
ATOM   11275 N N   . ALA D 1 383 ? -86.470 22.153  34.313  1.00 99.62  ? 458  ALA D N   1 
ATOM   11276 C CA  . ALA D 1 383 ? -86.265 22.793  33.016  1.00 90.86  ? 458  ALA D CA  1 
ATOM   11277 C C   . ALA D 1 383 ? -85.493 24.098  33.158  1.00 95.78  ? 458  ALA D C   1 
ATOM   11278 O O   . ALA D 1 383 ? -84.541 24.355  32.411  1.00 106.40 ? 458  ALA D O   1 
ATOM   11279 C CB  . ALA D 1 383 ? -87.610 23.030  32.329  1.00 105.59 ? 458  ALA D CB  1 
ATOM   11280 N N   . ASN D 1 384 ? -85.887 24.936  34.119  1.00 84.71  ? 459  ASN D N   1 
ATOM   11281 C CA  . ASN D 1 384 ? -85.193 26.205  34.292  1.00 97.33  ? 459  ASN D CA  1 
ATOM   11282 C C   . ASN D 1 384 ? -83.799 26.001  34.870  1.00 102.32 ? 459  ASN D C   1 
ATOM   11283 O O   . ASN D 1 384 ? -82.898 26.794  34.590  1.00 97.47  ? 459  ASN D O   1 
ATOM   11284 C CB  . ASN D 1 384 ? -86.010 27.149  35.172  1.00 121.02 ? 459  ASN D CB  1 
ATOM   11285 C CG  . ASN D 1 384 ? -85.854 28.602  34.762  1.00 132.24 ? 459  ASN D CG  1 
ATOM   11286 O OD1 . ASN D 1 384 ? -86.113 28.965  33.613  1.00 121.88 ? 459  ASN D OD1 1 
ATOM   11287 N ND2 . ASN D 1 384 ? -85.418 29.440  35.696  1.00 145.34 ? 459  ASN D ND2 1 
ATOM   11288 N N   . LEU D 1 385 ? -83.591 24.940  35.654  1.00 103.75 ? 460  LEU D N   1 
ATOM   11289 C CA  . LEU D 1 385 ? -82.235 24.619  36.093  1.00 95.00  ? 460  LEU D CA  1 
ATOM   11290 C C   . LEU D 1 385 ? -81.366 24.178  34.922  1.00 86.67  ? 460  LEU D C   1 
ATOM   11291 O O   . LEU D 1 385 ? -80.182 24.526  34.857  1.00 92.29  ? 460  LEU D O   1 
ATOM   11292 C CB  . LEU D 1 385 ? -82.261 23.543  37.178  1.00 98.03  ? 460  LEU D CB  1 
ATOM   11293 C CG  . LEU D 1 385 ? -82.785 23.942  38.559  1.00 107.97 ? 460  LEU D CG  1 
ATOM   11294 C CD1 . LEU D 1 385 ? -82.371 22.908  39.592  1.00 101.08 ? 460  LEU D CD1 1 
ATOM   11295 C CD2 . LEU D 1 385 ? -82.277 25.321  38.947  1.00 108.51 ? 460  LEU D CD2 1 
ATOM   11296 N N   . VAL D 1 386 ? -81.935 23.420  33.982  1.00 84.78  ? 461  VAL D N   1 
ATOM   11297 C CA  . VAL D 1 386 ? -81.189 23.035  32.787  1.00 77.08  ? 461  VAL D CA  1 
ATOM   11298 C C   . VAL D 1 386 ? -80.841 24.267  31.962  1.00 85.91  ? 461  VAL D C   1 
ATOM   11299 O O   . VAL D 1 386 ? -79.713 24.412  31.469  1.00 92.55  ? 461  VAL D O   1 
ATOM   11300 C CB  . VAL D 1 386 ? -81.994 22.012  31.964  1.00 69.22  ? 461  VAL D CB  1 
ATOM   11301 C CG1 . VAL D 1 386 ? -81.493 21.969  30.533  1.00 78.59  ? 461  VAL D CG1 1 
ATOM   11302 C CG2 . VAL D 1 386 ? -81.913 20.633  32.597  1.00 76.13  ? 461  VAL D CG2 1 
ATOM   11303 N N   . LYS D 1 387 ? -81.807 25.174  31.798  1.00 78.22  ? 462  LYS D N   1 
ATOM   11304 C CA  . LYS D 1 387 ? -81.543 26.410  31.070  1.00 85.35  ? 462  LYS D CA  1 
ATOM   11305 C C   . LYS D 1 387 ? -80.475 27.240  31.773  1.00 85.15  ? 462  LYS D C   1 
ATOM   11306 O O   . LYS D 1 387 ? -79.599 27.817  31.120  1.00 85.11  ? 462  LYS D O   1 
ATOM   11307 C CB  . LYS D 1 387 ? -82.839 27.205  30.912  1.00 91.89  ? 462  LYS D CB  1 
ATOM   11308 C CG  . LYS D 1 387 ? -83.898 26.487  30.091  1.00 89.10  ? 462  LYS D CG  1 
ATOM   11309 C CD  . LYS D 1 387 ? -85.299 26.915  30.497  1.00 109.43 ? 462  LYS D CD  1 
ATOM   11310 C CE  . LYS D 1 387 ? -85.737 28.171  29.764  1.00 121.51 ? 462  LYS D CE  1 
ATOM   11311 N NZ  . LYS D 1 387 ? -85.665 28.001  28.289  1.00 127.56 ? 462  LYS D NZ  1 
ATOM   11312 N N   . THR D 1 388 ? -80.526 27.295  33.108  1.00 81.62  ? 463  THR D N   1 
ATOM   11313 C CA  . THR D 1 388 ? -79.513 28.009  33.878  1.00 82.17  ? 463  THR D CA  1 
ATOM   11314 C C   . THR D 1 388 ? -78.140 27.383  33.688  1.00 88.58  ? 463  THR D C   1 
ATOM   11315 O O   . THR D 1 388 ? -77.129 28.090  33.627  1.00 94.61  ? 463  THR D O   1 
ATOM   11316 C CB  . THR D 1 388 ? -79.888 28.007  35.361  1.00 82.75  ? 463  THR D CB  1 
ATOM   11317 O OG1 . THR D 1 388 ? -81.249 28.429  35.517  1.00 95.44  ? 463  THR D OG1 1 
ATOM   11318 C CG2 . THR D 1 388 ? -78.980 28.944  36.142  1.00 99.09  ? 463  THR D CG2 1 
ATOM   11319 N N   . LEU D 1 389 ? -78.085 26.053  33.605  1.00 93.81  ? 464  LEU D N   1 
ATOM   11320 C CA  . LEU D 1 389 ? -76.821 25.375  33.340  1.00 88.19  ? 464  LEU D CA  1 
ATOM   11321 C C   . LEU D 1 389 ? -76.281 25.745  31.966  1.00 89.76  ? 464  LEU D C   1 
ATOM   11322 O O   . LEU D 1 389 ? -75.080 26.003  31.808  1.00 89.90  ? 464  LEU D O   1 
ATOM   11323 C CB  . LEU D 1 389 ? -77.008 23.863  33.458  1.00 70.06  ? 464  LEU D CB  1 
ATOM   11324 C CG  . LEU D 1 389 ? -75.739 23.023  33.332  1.00 75.44  ? 464  LEU D CG  1 
ATOM   11325 C CD1 . LEU D 1 389 ? -74.673 23.528  34.289  1.00 69.42  ? 464  LEU D CD1 1 
ATOM   11326 C CD2 . LEU D 1 389 ? -76.054 21.559  33.593  1.00 53.96  ? 464  LEU D CD2 1 
ATOM   11327 N N   . VAL D 1 390 ? -77.156 25.772  30.958  1.00 82.35  ? 465  VAL D N   1 
ATOM   11328 C CA  . VAL D 1 390 ? -76.735 26.172  29.617  1.00 73.50  ? 465  VAL D CA  1 
ATOM   11329 C C   . VAL D 1 390 ? -76.204 27.600  29.631  1.00 86.79  ? 465  VAL D C   1 
ATOM   11330 O O   . VAL D 1 390 ? -75.161 27.899  29.033  1.00 99.35  ? 465  VAL D O   1 
ATOM   11331 C CB  . VAL D 1 390 ? -77.896 26.008  28.620  1.00 68.19  ? 465  VAL D CB  1 
ATOM   11332 C CG1 . VAL D 1 390 ? -77.509 26.570  27.262  1.00 73.99  ? 465  VAL D CG1 1 
ATOM   11333 C CG2 . VAL D 1 390 ? -78.283 24.547  28.499  1.00 85.00  ? 465  VAL D CG2 1 
ATOM   11334 N N   . PHE D 1 391 ? -76.903 28.499  30.328  1.00 87.17  ? 466  PHE D N   1 
ATOM   11335 C CA  . PHE D 1 391 ? -76.486 29.898  30.370  1.00 97.06  ? 466  PHE D CA  1 
ATOM   11336 C C   . PHE D 1 391 ? -75.162 30.061  31.106  1.00 101.86 ? 466  PHE D C   1 
ATOM   11337 O O   . PHE D 1 391 ? -74.306 30.844  30.682  1.00 110.70 ? 466  PHE D O   1 
ATOM   11338 C CB  . PHE D 1 391 ? -77.568 30.765  31.018  1.00 98.15  ? 466  PHE D CB  1 
ATOM   11339 C CG  . PHE D 1 391 ? -78.931 30.617  30.394  1.00 106.13 ? 466  PHE D CG  1 
ATOM   11340 C CD1 . PHE D 1 391 ? -79.068 30.372  29.036  1.00 99.55  ? 466  PHE D CD1 1 
ATOM   11341 C CD2 . PHE D 1 391 ? -80.078 30.742  31.165  1.00 108.81 ? 466  PHE D CD2 1 
ATOM   11342 C CE1 . PHE D 1 391 ? -80.318 30.239  28.462  1.00 96.04  ? 466  PHE D CE1 1 
ATOM   11343 C CE2 . PHE D 1 391 ? -81.332 30.607  30.596  1.00 90.56  ? 466  PHE D CE2 1 
ATOM   11344 C CZ  . PHE D 1 391 ? -81.451 30.357  29.243  1.00 90.80  ? 466  PHE D CZ  1 
ATOM   11345 N N   . PHE D 1 392 ? -74.976 29.336  32.211  1.00 90.06  ? 467  PHE D N   1 
ATOM   11346 C CA  . PHE D 1 392 ? -73.709 29.391  32.932  1.00 91.21  ? 467  PHE D CA  1 
ATOM   11347 C C   . PHE D 1 392 ? -72.567 28.878  32.066  1.00 102.13 ? 467  PHE D C   1 
ATOM   11348 O O   . PHE D 1 392 ? -71.496 29.494  32.000  1.00 97.45  ? 467  PHE D O   1 
ATOM   11349 C CB  . PHE D 1 392 ? -73.805 28.580  34.223  1.00 79.76  ? 467  PHE D CB  1 
ATOM   11350 C CG  . PHE D 1 392 ? -72.483 28.364  34.897  1.00 97.08  ? 467  PHE D CG  1 
ATOM   11351 C CD1 . PHE D 1 392 ? -71.840 29.408  35.538  1.00 96.19  ? 467  PHE D CD1 1 
ATOM   11352 C CD2 . PHE D 1 392 ? -71.871 27.123  34.865  1.00 97.21  ? 467  PHE D CD2 1 
ATOM   11353 C CE1 . PHE D 1 392 ? -70.618 29.214  36.151  1.00 94.29  ? 467  PHE D CE1 1 
ATOM   11354 C CE2 . PHE D 1 392 ? -70.648 26.924  35.472  1.00 93.59  ? 467  PHE D CE2 1 
ATOM   11355 C CZ  . PHE D 1 392 ? -70.020 27.971  36.117  1.00 90.45  ? 467  PHE D CZ  1 
ATOM   11356 N N   . PHE D 1 393 ? -72.780 27.743  31.394  1.00 97.04  ? 468  PHE D N   1 
ATOM   11357 C CA  . PHE D 1 393 ? -71.742 27.179  30.540  1.00 84.90  ? 468  PHE D CA  1 
ATOM   11358 C C   . PHE D 1 393 ? -71.388 28.133  29.407  1.00 89.30  ? 468  PHE D C   1 
ATOM   11359 O O   . PHE D 1 393 ? -70.211 28.284  29.056  1.00 94.10  ? 468  PHE D O   1 
ATOM   11360 C CB  . PHE D 1 393 ? -72.202 25.826  29.995  1.00 80.93  ? 468  PHE D CB  1 
ATOM   11361 C CG  . PHE D 1 393 ? -71.346 25.294  28.884  1.00 98.36  ? 468  PHE D CG  1 
ATOM   11362 C CD1 . PHE D 1 393 ? -69.973 25.187  29.036  1.00 92.45  ? 468  PHE D CD1 1 
ATOM   11363 C CD2 . PHE D 1 393 ? -71.916 24.900  27.686  1.00 99.62  ? 468  PHE D CD2 1 
ATOM   11364 C CE1 . PHE D 1 393 ? -69.183 24.699  28.014  1.00 80.51  ? 468  PHE D CE1 1 
ATOM   11365 C CE2 . PHE D 1 393 ? -71.132 24.411  26.660  1.00 101.49 ? 468  PHE D CE2 1 
ATOM   11366 C CZ  . PHE D 1 393 ? -69.762 24.310  26.824  1.00 88.10  ? 468  PHE D CZ  1 
ATOM   11367 N N   . LEU D 1 394 ? -72.392 28.797  28.829  1.00 90.46  ? 469  LEU D N   1 
ATOM   11368 C CA  . LEU D 1 394 ? -72.120 29.765  27.772  1.00 100.66 ? 469  LEU D CA  1 
ATOM   11369 C C   . LEU D 1 394 ? -71.403 30.994  28.317  1.00 102.56 ? 469  LEU D C   1 
ATOM   11370 O O   . LEU D 1 394 ? -70.540 31.567  27.641  1.00 111.37 ? 469  LEU D O   1 
ATOM   11371 C CB  . LEU D 1 394 ? -73.422 30.170  27.081  1.00 93.72  ? 469  LEU D CB  1 
ATOM   11372 C CG  . LEU D 1 394 ? -73.913 29.271  25.947  1.00 94.94  ? 469  LEU D CG  1 
ATOM   11373 C CD1 . LEU D 1 394 ? -74.806 30.062  25.012  1.00 103.09 ? 469  LEU D CD1 1 
ATOM   11374 C CD2 . LEU D 1 394 ? -72.749 28.659  25.185  1.00 101.76 ? 469  LEU D CD2 1 
ATOM   11375 N N   . GLU D 1 395 ? -71.745 31.412  29.538  1.00 97.44  ? 470  GLU D N   1 
ATOM   11376 C CA  . GLU D 1 395 ? -71.141 32.608  30.114  1.00 108.84 ? 470  GLU D CA  1 
ATOM   11377 C C   . GLU D 1 395 ? -69.678 32.374  30.466  1.00 114.39 ? 470  GLU D C   1 
ATOM   11378 O O   . GLU D 1 395 ? -68.837 33.259  30.270  1.00 116.63 ? 470  GLU D O   1 
ATOM   11379 C CB  . GLU D 1 395 ? -71.927 33.049  31.351  1.00 112.98 ? 470  GLU D CB  1 
ATOM   11380 C CG  . GLU D 1 395 ? -73.126 33.940  31.050  1.00 114.92 ? 470  GLU D CG  1 
ATOM   11381 C CD  . GLU D 1 395 ? -74.367 33.540  31.830  1.00 129.91 ? 470  GLU D CD  1 
ATOM   11382 O OE1 . GLU D 1 395 ? -74.227 33.093  32.989  1.00 143.87 ? 470  GLU D OE1 1 
ATOM   11383 O OE2 . GLU D 1 395 ? -75.482 33.666  31.281  1.00 130.01 ? 470  GLU D OE2 1 
ATOM   11384 N N   . SER D 1 396 ? -69.355 31.194  30.990  1.00 117.68 ? 471  SER D N   1 
ATOM   11385 C CA  . SER D 1 396 ? -67.975 30.848  31.313  1.00 110.53 ? 471  SER D CA  1 
ATOM   11386 C C   . SER D 1 396 ? -67.245 30.507  30.021  1.00 102.44 ? 471  SER D C   1 
ATOM   11387 O O   . SER D 1 396 ? -67.444 29.429  29.451  1.00 108.50 ? 471  SER D O   1 
ATOM   11388 C CB  . SER D 1 396 ? -67.930 29.683  32.297  1.00 110.60 ? 471  SER D CB  1 
ATOM   11389 O OG  . SER D 1 396 ? -68.930 28.726  31.997  1.00 119.11 ? 471  SER D OG  1 
ATOM   11390 N N   . GLU D 1 397 ? -66.404 31.427  29.555  1.00 101.52 ? 472  GLU D N   1 
ATOM   11391 C CA  . GLU D 1 397 ? -65.639 31.241  28.330  1.00 111.05 ? 472  GLU D CA  1 
ATOM   11392 C C   . GLU D 1 397 ? -64.426 30.338  28.519  1.00 110.66 ? 472  GLU D C   1 
ATOM   11393 O O   . GLU D 1 397 ? -63.617 30.212  27.594  1.00 116.96 ? 472  GLU D O   1 
ATOM   11394 C CB  . GLU D 1 397 ? -65.192 32.601  27.786  1.00 109.57 ? 472  GLU D CB  1 
ATOM   11395 C CG  . GLU D 1 397 ? -64.738 33.576  28.863  1.00 110.09 ? 472  GLU D CG  1 
ATOM   11396 C CD  . GLU D 1 397 ? -64.249 34.894  28.293  1.00 129.97 ? 472  GLU D CD  1 
ATOM   11397 O OE1 . GLU D 1 397 ? -63.325 34.875  27.453  1.00 148.05 ? 472  GLU D OE1 1 
ATOM   11398 O OE2 . GLU D 1 397 ? -64.790 35.950  28.685  1.00 124.60 ? 472  GLU D OE2 1 
ATOM   11399 N N   . LEU D 1 398 ? -64.287 29.708  29.687  1.00 105.92 ? 473  LEU D N   1 
ATOM   11400 C CA  . LEU D 1 398 ? -63.097 28.909  29.961  1.00 99.83  ? 473  LEU D CA  1 
ATOM   11401 C C   . LEU D 1 398 ? -63.077 27.633  29.130  1.00 99.03  ? 473  LEU D C   1 
ATOM   11402 O O   . LEU D 1 398 ? -62.017 27.218  28.646  1.00 92.37  ? 473  LEU D O   1 
ATOM   11403 C CB  . LEU D 1 398 ? -63.020 28.581  31.452  1.00 95.69  ? 473  LEU D CB  1 
ATOM   11404 C CG  . LEU D 1 398 ? -62.731 29.749  32.396  1.00 89.38  ? 473  LEU D CG  1 
ATOM   11405 C CD1 . LEU D 1 398 ? -62.521 29.255  33.819  1.00 97.78  ? 473  LEU D CD1 1 
ATOM   11406 C CD2 . LEU D 1 398 ? -61.517 30.525  31.915  1.00 78.47  ? 473  LEU D CD2 1 
ATOM   11407 N N   . HIS D 1 399 ? -64.233 26.999  28.949  1.00 88.76  ? 474  HIS D N   1 
ATOM   11408 C CA  . HIS D 1 399 ? -64.322 25.715  28.271  1.00 85.53  ? 474  HIS D CA  1 
ATOM   11409 C C   . HIS D 1 399 ? -65.278 25.797  27.092  1.00 80.98  ? 474  HIS D C   1 
ATOM   11410 O O   . HIS D 1 399 ? -66.326 26.445  27.171  1.00 95.24  ? 474  HIS D O   1 
ATOM   11411 C CB  . HIS D 1 399 ? -64.783 24.622  29.233  1.00 88.57  ? 474  HIS D CB  1 
ATOM   11412 C CG  . HIS D 1 399 ? -63.663 23.960  29.970  1.00 89.58  ? 474  HIS D CG  1 
ATOM   11413 N ND1 . HIS D 1 399 ? -63.596 22.596  30.154  1.00 81.94  ? 474  HIS D ND1 1 
ATOM   11414 C CD2 . HIS D 1 399 ? -62.557 24.475  30.558  1.00 74.82  ? 474  HIS D CD2 1 
ATOM   11415 C CE1 . HIS D 1 399 ? -62.502 22.301  30.833  1.00 73.97  ? 474  HIS D CE1 1 
ATOM   11416 N NE2 . HIS D 1 399 ? -61.853 23.422  31.089  1.00 65.80  ? 474  HIS D NE2 1 
ATOM   11417 N N   . GLU D 1 400 ? -64.905 25.132  26.001  1.00 88.62  ? 475  GLU D N   1 
ATOM   11418 C CA  . GLU D 1 400 ? -65.771 24.985  24.841  1.00 78.18  ? 475  GLU D CA  1 
ATOM   11419 C C   . GLU D 1 400 ? -66.633 23.732  24.907  1.00 73.25  ? 475  GLU D C   1 
ATOM   11420 O O   . GLU D 1 400 ? -67.528 23.571  24.071  1.00 79.15  ? 475  GLU D O   1 
ATOM   11421 C CB  . GLU D 1 400 ? -64.937 24.962  23.556  1.00 80.84  ? 475  GLU D CB  1 
ATOM   11422 C CG  . GLU D 1 400 ? -63.856 26.029  23.490  1.00 92.26  ? 475  GLU D CG  1 
ATOM   11423 C CD  . GLU D 1 400 ? -63.205 26.105  22.123  1.00 105.73 ? 475  GLU D CD  1 
ATOM   11424 O OE1 . GLU D 1 400 ? -63.725 25.467  21.184  1.00 91.09  ? 475  GLU D OE1 1 
ATOM   11425 O OE2 . GLU D 1 400 ? -62.176 26.801  21.986  1.00 114.81 ? 475  GLU D OE2 1 
ATOM   11426 N N   . HIS D 1 401 ? -66.382 22.846  25.868  1.00 76.88  ? 476  HIS D N   1 
ATOM   11427 C CA  . HIS D 1 401 ? -67.196 21.660  26.076  1.00 77.82  ? 476  HIS D CA  1 
ATOM   11428 C C   . HIS D 1 401 ? -67.582 21.563  27.546  1.00 84.96  ? 476  HIS D C   1 
ATOM   11429 O O   . HIS D 1 401 ? -66.945 22.159  28.419  1.00 81.20  ? 476  HIS D O   1 
ATOM   11430 C CB  . HIS D 1 401 ? -66.469 20.386  25.602  1.00 75.34  ? 476  HIS D CB  1 
ATOM   11431 C CG  . HIS D 1 401 ? -65.143 20.152  26.258  1.00 67.60  ? 476  HIS D CG  1 
ATOM   11432 N ND1 . HIS D 1 401 ? -64.149 19.404  25.665  1.00 83.22  ? 476  HIS D ND1 1 
ATOM   11433 C CD2 . HIS D 1 401 ? -64.647 20.555  27.453  1.00 79.79  ? 476  HIS D CD2 1 
ATOM   11434 C CE1 . HIS D 1 401 ? -63.097 19.362  26.461  1.00 88.09  ? 476  HIS D CE1 1 
ATOM   11435 N NE2 . HIS D 1 401 ? -63.373 20.051  27.553  1.00 87.77  ? 476  HIS D NE2 1 
ATOM   11436 N N   . ALA D 1 402 ? -68.645 20.804  27.809  1.00 78.04  ? 477  ALA D N   1 
ATOM   11437 C CA  . ALA D 1 402 ? -69.219 20.693  29.142  1.00 81.12  ? 477  ALA D CA  1 
ATOM   11438 C C   . ALA D 1 402 ? -68.770 19.441  29.881  1.00 79.52  ? 477  ALA D C   1 
ATOM   11439 O O   . ALA D 1 402 ? -69.324 19.133  30.940  1.00 89.50  ? 477  ALA D O   1 
ATOM   11440 C CB  . ALA D 1 402 ? -70.746 20.721  29.060  1.00 77.26  ? 477  ALA D CB  1 
ATOM   11441 N N   . ALA D 1 403 ? -67.780 18.717  29.354  1.00 67.92  ? 478  ALA D N   1 
ATOM   11442 C CA  . ALA D 1 403 ? -67.386 17.451  29.964  1.00 72.83  ? 478  ALA D CA  1 
ATOM   11443 C C   . ALA D 1 403 ? -66.909 17.654  31.398  1.00 64.01  ? 478  ALA D C   1 
ATOM   11444 O O   . ALA D 1 403 ? -67.335 16.941  32.315  1.00 66.03  ? 478  ALA D O   1 
ATOM   11445 C CB  . ALA D 1 403 ? -66.300 16.782  29.123  1.00 72.43  ? 478  ALA D CB  1 
ATOM   11446 N N   . TYR D 1 404 ? -66.046 18.646  31.615  1.00 56.51  ? 479  TYR D N   1 
ATOM   11447 C CA  . TYR D 1 404 ? -65.457 18.834  32.933  1.00 68.67  ? 479  TYR D CA  1 
ATOM   11448 C C   . TYR D 1 404 ? -66.417 19.528  33.893  1.00 79.40  ? 479  TYR D C   1 
ATOM   11449 O O   . TYR D 1 404 ? -66.414 19.225  35.092  1.00 83.69  ? 479  TYR D O   1 
ATOM   11450 C CB  . TYR D 1 404 ? -64.146 19.602  32.788  1.00 61.21  ? 479  TYR D CB  1 
ATOM   11451 C CG  . TYR D 1 404 ? -63.099 18.779  32.072  1.00 71.42  ? 479  TYR D CG  1 
ATOM   11452 C CD1 . TYR D 1 404 ? -62.578 17.628  32.649  1.00 77.64  ? 479  TYR D CD1 1 
ATOM   11453 C CD2 . TYR D 1 404 ? -62.686 19.109  30.789  1.00 73.89  ? 479  TYR D CD2 1 
ATOM   11454 C CE1 . TYR D 1 404 ? -61.633 16.863  31.990  1.00 77.21  ? 479  TYR D CE1 1 
ATOM   11455 C CE2 . TYR D 1 404 ? -61.748 18.352  30.121  1.00 74.82  ? 479  TYR D CE2 1 
ATOM   11456 C CZ  . TYR D 1 404 ? -61.225 17.228  30.724  1.00 77.27  ? 479  TYR D CZ  1 
ATOM   11457 O OH  . TYR D 1 404 ? -60.289 16.470  30.056  1.00 79.14  ? 479  TYR D OH  1 
ATOM   11458 N N   . LEU D 1 405 ? -67.259 20.431  33.387  1.00 73.74  ? 480  LEU D N   1 
ATOM   11459 C CA  . LEU D 1 405 ? -68.351 20.973  34.190  1.00 67.60  ? 480  LEU D CA  1 
ATOM   11460 C C   . LEU D 1 405 ? -69.287 19.861  34.662  1.00 69.74  ? 480  LEU D C   1 
ATOM   11461 O O   . LEU D 1 405 ? -69.633 19.775  35.853  1.00 77.86  ? 480  LEU D O   1 
ATOM   11462 C CB  . LEU D 1 405 ? -69.116 22.009  33.365  1.00 61.27  ? 480  LEU D CB  1 
ATOM   11463 C CG  . LEU D 1 405 ? -70.371 22.663  33.940  1.00 62.71  ? 480  LEU D CG  1 
ATOM   11464 C CD1 . LEU D 1 405 ? -70.035 23.415  35.214  1.00 68.32  ? 480  LEU D CD1 1 
ATOM   11465 C CD2 . LEU D 1 405 ? -71.007 23.586  32.911  1.00 70.74  ? 480  LEU D CD2 1 
ATOM   11466 N N   . VAL D 1 406 ? -69.715 19.005  33.729  1.00 56.20  ? 481  VAL D N   1 
ATOM   11467 C CA  . VAL D 1 406 ? -70.612 17.901  34.061  1.00 55.88  ? 481  VAL D CA  1 
ATOM   11468 C C   . VAL D 1 406 ? -69.951 16.962  35.060  1.00 63.94  ? 481  VAL D C   1 
ATOM   11469 O O   . VAL D 1 406 ? -70.604 16.443  35.973  1.00 61.12  ? 481  VAL D O   1 
ATOM   11470 C CB  . VAL D 1 406 ? -71.042 17.161  32.779  1.00 42.56  ? 481  VAL D CB  1 
ATOM   11471 C CG1 . VAL D 1 406 ? -71.477 15.733  33.092  1.00 60.46  ? 481  VAL D CG1 1 
ATOM   11472 C CG2 . VAL D 1 406 ? -72.150 17.919  32.068  1.00 53.46  ? 481  VAL D CG2 1 
ATOM   11473 N N   . ASP D 1 407 ? -68.644 16.732  34.913  1.00 70.83  ? 482  ASP D N   1 
ATOM   11474 C CA  . ASP D 1 407 ? -67.945 15.894  35.881  1.00 69.16  ? 482  ASP D CA  1 
ATOM   11475 C C   . ASP D 1 407 ? -67.916 16.542  37.258  1.00 72.55  ? 482  ASP D C   1 
ATOM   11476 O O   . ASP D 1 407 ? -68.145 15.871  38.272  1.00 77.69  ? 482  ASP D O   1 
ATOM   11477 C CB  . ASP D 1 407 ? -66.526 15.602  35.405  1.00 66.93  ? 482  ASP D CB  1 
ATOM   11478 C CG  . ASP D 1 407 ? -65.765 14.718  36.369  1.00 71.70  ? 482  ASP D CG  1 
ATOM   11479 O OD1 . ASP D 1 407 ? -66.233 13.589  36.631  1.00 48.81  ? 482  ASP D OD1 1 
ATOM   11480 O OD2 . ASP D 1 407 ? -64.708 15.155  36.871  1.00 79.25  ? 482  ASP D OD2 1 
ATOM   11481 N N   . SER D 1 408 ? -67.635 17.847  37.315  1.00 71.18  ? 483  SER D N   1 
ATOM   11482 C CA  . SER D 1 408 ? -67.587 18.541  38.597  1.00 72.33  ? 483  SER D CA  1 
ATOM   11483 C C   . SER D 1 408 ? -68.922 18.457  39.324  1.00 74.38  ? 483  SER D C   1 
ATOM   11484 O O   . SER D 1 408 ? -68.960 18.267  40.546  1.00 72.61  ? 483  SER D O   1 
ATOM   11485 C CB  . SER D 1 408 ? -67.186 20.002  38.394  1.00 70.26  ? 483  SER D CB  1 
ATOM   11486 O OG  . SER D 1 408 ? -66.185 20.128  37.401  1.00 72.39  ? 483  SER D OG  1 
ATOM   11487 N N   . MET D 1 409 ? -70.028 18.587  38.596  1.00 71.93  ? 484  MET D N   1 
ATOM   11488 C CA  . MET D 1 409 ? -71.336 18.587  39.240  1.00 69.36  ? 484  MET D CA  1 
ATOM   11489 C C   . MET D 1 409 ? -72.049 17.241  39.177  1.00 74.15  ? 484  MET D C   1 
ATOM   11490 O O   . MET D 1 409 ? -73.224 17.162  39.550  1.00 79.34  ? 484  MET D O   1 
ATOM   11491 C CB  . MET D 1 409 ? -72.229 19.666  38.639  1.00 53.22  ? 484  MET D CB  1 
ATOM   11492 C CG  . MET D 1 409 ? -72.105 21.009  39.324  1.00 62.73  ? 484  MET D CG  1 
ATOM   11493 S SD  . MET D 1 409 ? -73.296 22.179  38.662  1.00 86.01  ? 484  MET D SD  1 
ATOM   11494 C CE  . MET D 1 409 ? -72.942 22.022  36.918  1.00 83.10  ? 484  MET D CE  1 
ATOM   11495 N N   . TRP D 1 410 ? -71.376 16.179  38.726  1.00 75.44  ? 485  TRP D N   1 
ATOM   11496 C CA  . TRP D 1 410 ? -72.069 14.905  38.557  1.00 78.91  ? 485  TRP D CA  1 
ATOM   11497 C C   . TRP D 1 410 ? -72.427 14.289  39.904  1.00 80.14  ? 485  TRP D C   1 
ATOM   11498 O O   . TRP D 1 410 ? -73.496 13.687  40.053  1.00 86.34  ? 485  TRP D O   1 
ATOM   11499 C CB  . TRP D 1 410 ? -71.215 13.941  37.730  1.00 73.44  ? 485  TRP D CB  1 
ATOM   11500 C CG  . TRP D 1 410 ? -72.001 12.800  37.139  1.00 77.55  ? 485  TRP D CG  1 
ATOM   11501 C CD1 . TRP D 1 410 ? -72.502 12.722  35.869  1.00 62.24  ? 485  TRP D CD1 1 
ATOM   11502 C CD2 . TRP D 1 410 ? -72.395 11.590  37.799  1.00 86.16  ? 485  TRP D CD2 1 
ATOM   11503 N NE1 . TRP D 1 410 ? -73.172 11.535  35.696  1.00 55.12  ? 485  TRP D NE1 1 
ATOM   11504 C CE2 . TRP D 1 410 ? -73.122 10.823  36.866  1.00 95.66  ? 485  TRP D CE2 1 
ATOM   11505 C CE3 . TRP D 1 410 ? -72.199 11.077  39.087  1.00 100.89 ? 485  TRP D CE3 1 
ATOM   11506 C CZ2 . TRP D 1 410 ? -73.655 9.572   37.180  1.00 108.93 ? 485  TRP D CZ2 1 
ATOM   11507 C CZ3 . TRP D 1 410 ? -72.731 9.836   39.397  1.00 121.88 ? 485  TRP D CZ3 1 
ATOM   11508 C CH2 . TRP D 1 410 ? -73.449 9.098   38.448  1.00 112.29 ? 485  TRP D CH2 1 
ATOM   11509 N N   . ASP D 1 411 ? -71.556 14.444  40.902  1.00 80.10  ? 486  ASP D N   1 
ATOM   11510 C CA  . ASP D 1 411 ? -71.798 13.806  42.190  1.00 77.74  ? 486  ASP D CA  1 
ATOM   11511 C C   . ASP D 1 411 ? -72.970 14.440  42.926  1.00 74.01  ? 486  ASP D C   1 
ATOM   11512 O O   . ASP D 1 411 ? -73.687 13.748  43.657  1.00 81.19  ? 486  ASP D O   1 
ATOM   11513 C CB  . ASP D 1 411 ? -70.539 13.869  43.049  1.00 103.68 ? 486  ASP D CB  1 
ATOM   11514 C CG  . ASP D 1 411 ? -69.508 12.851  42.632  1.00 109.10 ? 486  ASP D CG  1 
ATOM   11515 O OD1 . ASP D 1 411 ? -69.801 11.639  42.711  1.00 113.75 ? 486  ASP D OD1 1 
ATOM   11516 O OD2 . ASP D 1 411 ? -68.408 13.265  42.211  1.00 116.72 ? 486  ASP D OD2 1 
ATOM   11517 N N   . CYS D 1 412 ? -73.182 15.744  42.753  1.00 77.94  ? 487  CYS D N   1 
ATOM   11518 C CA  . CYS D 1 412 ? -74.242 16.458  43.455  1.00 65.43  ? 487  CYS D CA  1 
ATOM   11519 C C   . CYS D 1 412 ? -75.501 16.629  42.613  1.00 66.16  ? 487  CYS D C   1 
ATOM   11520 O O   . CYS D 1 412 ? -76.602 16.337  43.087  1.00 76.64  ? 487  CYS D O   1 
ATOM   11521 C CB  . CYS D 1 412 ? -73.741 17.829  43.922  1.00 68.62  ? 487  CYS D CB  1 
ATOM   11522 S SG  . CYS D 1 412 ? -73.031 18.863  42.625  1.00 86.90  ? 487  CYS D SG  1 
ATOM   11523 N N   . ALA D 1 413 ? -75.364 17.102  41.372  1.00 70.29  ? 488  ALA D N   1 
ATOM   11524 C CA  . ALA D 1 413 ? -76.507 17.352  40.501  1.00 73.43  ? 488  ALA D CA  1 
ATOM   11525 C C   . ALA D 1 413 ? -76.863 16.148  39.638  1.00 71.69  ? 488  ALA D C   1 
ATOM   11526 O O   . ALA D 1 413 ? -77.289 16.319  38.490  1.00 78.47  ? 488  ALA D O   1 
ATOM   11527 C CB  . ALA D 1 413 ? -76.241 18.573  39.619  1.00 60.23  ? 488  ALA D CB  1 
ATOM   11528 N N   . THR D 1 414 ? -76.705 14.934  40.166  1.00 75.68  ? 489  THR D N   1 
ATOM   11529 C CA  . THR D 1 414 ? -76.907 13.740  39.354  1.00 82.75  ? 489  THR D CA  1 
ATOM   11530 C C   . THR D 1 414 ? -78.336 13.657  38.828  1.00 80.40  ? 489  THR D C   1 
ATOM   11531 O O   . THR D 1 414 ? -78.559 13.257  37.680  1.00 85.58  ? 489  THR D O   1 
ATOM   11532 C CB  . THR D 1 414 ? -76.556 12.491  40.164  1.00 87.61  ? 489  THR D CB  1 
ATOM   11533 O OG1 . THR D 1 414 ? -76.739 11.324  39.353  1.00 100.98 ? 489  THR D OG1 1 
ATOM   11534 C CG2 . THR D 1 414 ? -77.420 12.392  41.417  1.00 89.32  ? 489  THR D CG2 1 
ATOM   11535 N N   . GLU D 1 415 ? -79.318 14.049  39.641  1.00 81.35  ? 490  GLU D N   1 
ATOM   11536 C CA  . GLU D 1 415 ? -80.706 13.907  39.219  1.00 92.29  ? 490  GLU D CA  1 
ATOM   11537 C C   . GLU D 1 415 ? -81.055 14.917  38.131  1.00 88.93  ? 490  GLU D C   1 
ATOM   11538 O O   . GLU D 1 415 ? -81.774 14.589  37.179  1.00 84.95  ? 490  GLU D O   1 
ATOM   11539 C CB  . GLU D 1 415 ? -81.629 14.060  40.423  1.00 103.17 ? 490  GLU D CB  1 
ATOM   11540 C CG  . GLU D 1 415 ? -83.086 13.948  40.071  1.00 113.40 ? 490  GLU D CG  1 
ATOM   11541 C CD  . GLU D 1 415 ? -83.728 15.300  39.982  1.00 130.92 ? 490  GLU D CD  1 
ATOM   11542 O OE1 . GLU D 1 415 ? -83.027 16.302  40.236  1.00 129.80 ? 490  GLU D OE1 1 
ATOM   11543 O OE2 . GLU D 1 415 ? -84.934 15.369  39.664  1.00 146.22 ? 490  GLU D OE2 1 
ATOM   11544 N N   . LEU D 1 416 ? -80.562 16.151  38.261  1.00 76.40  ? 491  LEU D N   1 
ATOM   11545 C CA  . LEU D 1 416 ? -80.760 17.149  37.214  1.00 73.42  ? 491  LEU D CA  1 
ATOM   11546 C C   . LEU D 1 416 ? -80.015 16.762  35.943  1.00 77.95  ? 491  LEU D C   1 
ATOM   11547 O O   . LEU D 1 416 ? -80.565 16.836  34.838  1.00 80.56  ? 491  LEU D O   1 
ATOM   11548 C CB  . LEU D 1 416 ? -80.299 18.520  37.711  1.00 66.69  ? 491  LEU D CB  1 
ATOM   11549 C CG  . LEU D 1 416 ? -80.006 19.594  36.660  1.00 61.79  ? 491  LEU D CG  1 
ATOM   11550 C CD1 . LEU D 1 416 ? -81.294 20.119  36.049  1.00 84.56  ? 491  LEU D CD1 1 
ATOM   11551 C CD2 . LEU D 1 416 ? -79.192 20.729  37.262  1.00 58.98  ? 491  LEU D CD2 1 
ATOM   11552 N N   . LEU D 1 417 ? -78.755 16.340  36.085  1.00 76.95  ? 492  LEU D N   1 
ATOM   11553 C CA  . LEU D 1 417 ? -77.935 16.019  34.921  1.00 69.17  ? 492  LEU D CA  1 
ATOM   11554 C C   . LEU D 1 417 ? -78.465 14.807  34.164  1.00 67.39  ? 492  LEU D C   1 
ATOM   11555 O O   . LEU D 1 417 ? -78.234 14.688  32.955  1.00 70.46  ? 492  LEU D O   1 
ATOM   11556 C CB  . LEU D 1 417 ? -76.487 15.781  35.355  1.00 70.55  ? 492  LEU D CB  1 
ATOM   11557 C CG  . LEU D 1 417 ? -75.682 16.995  35.821  1.00 66.67  ? 492  LEU D CG  1 
ATOM   11558 C CD1 . LEU D 1 417 ? -74.217 16.631  35.995  1.00 64.74  ? 492  LEU D CD1 1 
ATOM   11559 C CD2 . LEU D 1 417 ? -75.829 18.143  34.839  1.00 60.75  ? 492  LEU D CD2 1 
ATOM   11560 N N   . LYS D 1 418 ? -79.167 13.904  34.845  1.00 55.99  ? 493  LYS D N   1 
ATOM   11561 C CA  . LYS D 1 418 ? -79.700 12.701  34.225  1.00 68.51  ? 493  LYS D CA  1 
ATOM   11562 C C   . LYS D 1 418 ? -81.161 12.858  33.819  1.00 82.03  ? 493  LYS D C   1 
ATOM   11563 O O   . LYS D 1 418 ? -81.818 11.860  33.500  1.00 86.54  ? 493  LYS D O   1 
ATOM   11564 C CB  . LYS D 1 418 ? -79.529 11.508  35.167  1.00 73.46  ? 493  LYS D CB  1 
ATOM   11565 C CG  . LYS D 1 418 ? -78.071 11.132  35.411  1.00 64.85  ? 493  LYS D CG  1 
ATOM   11566 C CD  . LYS D 1 418 ? -77.906 10.196  36.607  1.00 79.68  ? 493  LYS D CD  1 
ATOM   11567 C CE  . LYS D 1 418 ? -78.287 8.761   36.271  1.00 93.46  ? 493  LYS D CE  1 
ATOM   11568 N NZ  . LYS D 1 418 ? -77.272 8.126   35.386  1.00 85.10  ? 493  LYS D NZ  1 
ATOM   11569 N N   . ASP D 1 419 ? -81.681 14.087  33.824  1.00 78.37  ? 494  ASP D N   1 
ATOM   11570 C CA  . ASP D 1 419 ? -83.043 14.364  33.366  1.00 87.87  ? 494  ASP D CA  1 
ATOM   11571 C C   . ASP D 1 419 ? -83.008 14.606  31.857  1.00 87.93  ? 494  ASP D C   1 
ATOM   11572 O O   . ASP D 1 419 ? -83.267 15.701  31.353  1.00 89.80  ? 494  ASP D O   1 
ATOM   11573 C CB  . ASP D 1 419 ? -83.627 15.555  34.116  1.00 103.50 ? 494  ASP D CB  1 
ATOM   11574 C CG  . ASP D 1 419 ? -85.136 15.637  34.001  1.00 100.43 ? 494  ASP D CG  1 
ATOM   11575 O OD1 . ASP D 1 419 ? -85.725 14.802  33.286  1.00 102.45 ? 494  ASP D OD1 1 
ATOM   11576 O OD2 . ASP D 1 419 ? -85.731 16.542  34.621  1.00 100.21 ? 494  ASP D OD2 1 
ATOM   11577 N N   . TRP D 1 420 ? -82.676 13.534  31.132  1.00 94.18  ? 495  TRP D N   1 
ATOM   11578 C CA  . TRP D 1 420 ? -82.515 13.634  29.684  1.00 98.52  ? 495  TRP D CA  1 
ATOM   11579 C C   . TRP D 1 420 ? -83.836 13.921  28.985  1.00 97.31  ? 495  TRP D C   1 
ATOM   11580 O O   . TRP D 1 420 ? -83.845 14.542  27.917  1.00 100.08 ? 495  TRP D O   1 
ATOM   11581 C CB  . TRP D 1 420 ? -81.902 12.347  29.134  1.00 95.97  ? 495  TRP D CB  1 
ATOM   11582 C CG  . TRP D 1 420 ? -80.565 12.037  29.707  1.00 88.54  ? 495  TRP D CG  1 
ATOM   11583 C CD1 . TRP D 1 420 ? -79.430 12.782  29.593  1.00 77.42  ? 495  TRP D CD1 1 
ATOM   11584 C CD2 . TRP D 1 420 ? -80.220 10.896  30.497  1.00 82.27  ? 495  TRP D CD2 1 
ATOM   11585 N NE1 . TRP D 1 420 ? -78.396 12.174  30.261  1.00 79.67  ? 495  TRP D NE1 1 
ATOM   11586 C CE2 . TRP D 1 420 ? -78.856 11.013  30.825  1.00 87.87  ? 495  TRP D CE2 1 
ATOM   11587 C CE3 . TRP D 1 420 ? -80.932 9.786   30.958  1.00 84.51  ? 495  TRP D CE3 1 
ATOM   11588 C CZ2 . TRP D 1 420 ? -78.191 10.062  31.591  1.00 91.73  ? 495  TRP D CZ2 1 
ATOM   11589 C CZ3 . TRP D 1 420 ? -80.270 8.842   31.719  1.00 86.67  ? 495  TRP D CZ3 1 
ATOM   11590 C CH2 . TRP D 1 420 ? -78.914 8.985   32.028  1.00 84.73  ? 495  TRP D CH2 1 
ATOM   11591 N N   . GLU D 1 421 ? -84.950 13.468  29.562  1.00 104.90 ? 496  GLU D N   1 
ATOM   11592 C CA  . GLU D 1 421 ? -86.257 13.727  28.966  1.00 112.17 ? 496  GLU D CA  1 
ATOM   11593 C C   . GLU D 1 421 ? -86.520 15.225  28.871  1.00 109.71 ? 496  GLU D C   1 
ATOM   11594 O O   . GLU D 1 421 ? -86.935 15.734  27.821  1.00 108.65 ? 496  GLU D O   1 
ATOM   11595 C CB  . GLU D 1 421 ? -87.342 13.015  29.783  1.00 88.49  ? 496  GLU D CB  1 
ATOM   11596 C CG  . GLU D 1 421 ? -88.776 13.193  29.292  1.00 120.77 ? 496  GLU D CG  1 
ATOM   11597 C CD  . GLU D 1 421 ? -89.419 14.479  29.787  1.00 153.12 ? 496  GLU D CD  1 
ATOM   11598 O OE1 . GLU D 1 421 ? -89.566 14.633  31.018  1.00 152.07 ? 496  GLU D OE1 1 
ATOM   11599 O OE2 . GLU D 1 421 ? -89.786 15.329  28.949  1.00 188.15 ? 496  GLU D OE2 1 
ATOM   11600 N N   . CYS D 1 422 ? -86.251 15.952  29.958  1.00 98.17  ? 497  CYS D N   1 
ATOM   11601 C CA  . CYS D 1 422 ? -86.479 17.393  29.971  1.00 101.13 ? 497  CYS D CA  1 
ATOM   11602 C C   . CYS D 1 422 ? -85.546 18.117  29.008  1.00 99.50  ? 497  CYS D C   1 
ATOM   11603 O O   . CYS D 1 422 ? -85.963 19.057  28.322  1.00 99.22  ? 497  CYS D O   1 
ATOM   11604 C CB  . CYS D 1 422 ? -86.306 17.930  31.390  1.00 101.62 ? 497  CYS D CB  1 
ATOM   11605 S SG  . CYS D 1 422 ? -86.217 19.721  31.481  1.00 102.96 ? 497  CYS D SG  1 
ATOM   11606 N N   . MET D 1 423 ? -84.280 17.701  28.947  1.00 99.24  ? 498  MET D N   1 
ATOM   11607 C CA  . MET D 1 423 ? -83.332 18.336  28.036  1.00 95.61  ? 498  MET D CA  1 
ATOM   11608 C C   . MET D 1 423 ? -83.748 18.125  26.585  1.00 105.04 ? 498  MET D C   1 
ATOM   11609 O O   . MET D 1 423 ? -83.783 19.071  25.786  1.00 104.00 ? 498  MET D O   1 
ATOM   11610 C CB  . MET D 1 423 ? -81.931 17.778  28.284  1.00 97.02  ? 498  MET D CB  1 
ATOM   11611 C CG  . MET D 1 423 ? -81.138 18.531  29.336  1.00 104.62 ? 498  MET D CG  1 
ATOM   11612 S SD  . MET D 1 423 ? -79.479 17.864  29.552  1.00 100.50 ? 498  MET D SD  1 
ATOM   11613 C CE  . MET D 1 423 ? -79.845 16.120  29.684  1.00 74.55  ? 498  MET D CE  1 
ATOM   11614 N N   . ASN D 1 424 ? -84.069 16.879  26.231  1.00 105.38 ? 499  ASN D N   1 
ATOM   11615 C CA  . ASN D 1 424 ? -84.540 16.577  24.885  1.00 100.21 ? 499  ASN D CA  1 
ATOM   11616 C C   . ASN D 1 424 ? -85.789 17.382  24.545  1.00 115.51 ? 499  ASN D C   1 
ATOM   11617 O O   . ASN D 1 424 ? -85.916 17.897  23.428  1.00 116.43 ? 499  ASN D O   1 
ATOM   11618 C CB  . ASN D 1 424 ? -84.806 15.076  24.758  1.00 95.70  ? 499  ASN D CB  1 
ATOM   11619 C CG  . ASN D 1 424 ? -85.651 14.732  23.551  1.00 120.69 ? 499  ASN D CG  1 
ATOM   11620 O OD1 . ASN D 1 424 ? -85.275 15.011  22.413  1.00 136.55 ? 499  ASN D OD1 1 
ATOM   11621 N ND2 . ASN D 1 424 ? -86.806 14.122  23.795  1.00 120.30 ? 499  ASN D ND2 1 
ATOM   11622 N N   . SER D 1 425 ? -86.719 17.509  25.498  1.00 108.53 ? 500  SER D N   1 
ATOM   11623 C CA  . SER D 1 425 ? -87.916 18.313  25.261  1.00 103.27 ? 500  SER D CA  1 
ATOM   11624 C C   . SER D 1 425 ? -87.561 19.775  25.021  1.00 105.42 ? 500  SER D C   1 
ATOM   11625 O O   . SER D 1 425 ? -88.112 20.415  24.117  1.00 122.46 ? 500  SER D O   1 
ATOM   11626 C CB  . SER D 1 425 ? -88.873 18.183  26.444  1.00 101.14 ? 500  SER D CB  1 
ATOM   11627 O OG  . SER D 1 425 ? -89.156 16.823  26.721  1.00 106.93 ? 500  SER D OG  1 
ATOM   11628 N N   . LEU D 1 426 ? -86.647 20.324  25.828  1.00 95.84  ? 501  LEU D N   1 
ATOM   11629 C CA  . LEU D 1 426 ? -86.161 21.680  25.600  1.00 96.14  ? 501  LEU D CA  1 
ATOM   11630 C C   . LEU D 1 426 ? -85.511 21.836  24.234  1.00 97.67  ? 501  LEU D C   1 
ATOM   11631 O O   . LEU D 1 426 ? -85.480 22.949  23.700  1.00 106.87 ? 501  LEU D O   1 
ATOM   11632 C CB  . LEU D 1 426 ? -85.168 22.078  26.694  1.00 107.60 ? 501  LEU D CB  1 
ATOM   11633 C CG  . LEU D 1 426 ? -85.781 22.538  28.016  1.00 91.87  ? 501  LEU D CG  1 
ATOM   11634 C CD1 . LEU D 1 426 ? -84.714 22.654  29.088  1.00 87.96  ? 501  LEU D CD1 1 
ATOM   11635 C CD2 . LEU D 1 426 ? -86.520 23.856  27.838  1.00 99.77  ? 501  LEU D CD2 1 
ATOM   11636 N N   . LEU D 1 427 ? -84.990 20.753  23.662  1.00 108.20 ? 502  LEU D N   1 
ATOM   11637 C CA  . LEU D 1 427 ? -84.473 20.779  22.301  1.00 120.35 ? 502  LEU D CA  1 
ATOM   11638 C C   . LEU D 1 427 ? -85.500 20.352  21.258  1.00 117.07 ? 502  LEU D C   1 
ATOM   11639 O O   . LEU D 1 427 ? -85.205 20.421  20.061  1.00 119.66 ? 502  LEU D O   1 
ATOM   11640 C CB  . LEU D 1 427 ? -83.236 19.882  22.190  1.00 107.14 ? 502  LEU D CB  1 
ATOM   11641 C CG  . LEU D 1 427 ? -82.032 20.347  23.005  1.00 97.94  ? 502  LEU D CG  1 
ATOM   11642 C CD1 . LEU D 1 427 ? -81.137 19.171  23.336  1.00 86.34  ? 502  LEU D CD1 1 
ATOM   11643 C CD2 . LEU D 1 427 ? -81.263 21.427  22.255  1.00 95.50  ? 502  LEU D CD2 1 
ATOM   11644 N N   . LEU D 1 428 ? -86.694 19.925  21.672  1.00 121.34 ? 503  LEU D N   1 
ATOM   11645 C CA  . LEU D 1 428 ? -87.655 19.356  20.733  1.00 125.38 ? 503  LEU D CA  1 
ATOM   11646 C C   . LEU D 1 428 ? -88.981 20.106  20.706  1.00 130.22 ? 503  LEU D C   1 
ATOM   11647 O O   . LEU D 1 428 ? -89.248 20.861  19.765  1.00 131.18 ? 503  LEU D O   1 
ATOM   11648 C CB  . LEU D 1 428 ? -87.906 17.883  21.063  1.00 122.73 ? 503  LEU D CB  1 
ATOM   11649 C CG  . LEU D 1 428 ? -87.857 16.901  19.893  1.00 117.24 ? 503  LEU D CG  1 
ATOM   11650 C CD1 . LEU D 1 428 ? -86.547 17.034  19.144  1.00 101.58 ? 503  LEU D CD1 1 
ATOM   11651 C CD2 . LEU D 1 428 ? -88.050 15.475  20.387  1.00 116.69 ? 503  LEU D CD2 1 
ATOM   11652 N N   . GLU D 1 429 ? -89.823 19.892  21.723  1.00 131.62 ? 504  GLU D N   1 
ATOM   11653 C CA  . GLU D 1 429 ? -91.182 20.425  21.682  1.00 142.22 ? 504  GLU D CA  1 
ATOM   11654 C C   . GLU D 1 429 ? -91.185 21.948  21.615  1.00 152.46 ? 504  GLU D C   1 
ATOM   11655 O O   . GLU D 1 429 ? -92.002 22.536  20.896  1.00 159.71 ? 504  GLU D O   1 
ATOM   11656 C CB  . GLU D 1 429 ? -91.984 19.928  22.888  1.00 126.00 ? 504  GLU D CB  1 
ATOM   11657 C CG  . GLU D 1 429 ? -91.300 20.079  24.241  1.00 126.46 ? 504  GLU D CG  1 
ATOM   11658 C CD  . GLU D 1 429 ? -92.131 19.489  25.368  1.00 136.14 ? 504  GLU D CD  1 
ATOM   11659 O OE1 . GLU D 1 429 ? -92.412 18.274  25.317  1.00 116.52 ? 504  GLU D OE1 1 
ATOM   11660 O OE2 . GLU D 1 429 ? -92.511 20.232  26.297  1.00 140.83 ? 504  GLU D OE2 1 
ATOM   11661 N N   . GLU D 1 430 ? -90.267 22.598  22.344  1.00 146.95 ? 505  GLU D N   1 
ATOM   11662 C CA  . GLU D 1 430 ? -90.076 24.046  22.357  1.00 158.71 ? 505  GLU D CA  1 
ATOM   11663 C C   . GLU D 1 430 ? -91.405 24.801  22.357  1.00 157.25 ? 505  GLU D C   1 
ATOM   11664 O O   . GLU D 1 430 ? -91.619 25.663  21.492  1.00 142.21 ? 505  GLU D O   1 
ATOM   11665 C CB  . GLU D 1 430 ? -89.224 24.471  21.158  1.00 159.10 ? 505  GLU D CB  1 
ATOM   11666 C CG  . GLU D 1 430 ? -87.882 23.764  21.093  1.00 159.89 ? 505  GLU D CG  1 
ATOM   11667 C CD  . GLU D 1 430 ? -87.000 24.255  19.962  1.00 161.07 ? 505  GLU D CD  1 
ATOM   11668 O OE1 . GLU D 1 430 ? -87.419 25.161  19.212  1.00 168.26 ? 505  GLU D OE1 1 
ATOM   11669 O OE2 . GLU D 1 430 ? -85.876 23.729  19.827  1.00 144.45 ? 505  GLU D OE2 1 
ATOM   11670 N N   . PRO D 1 431 ? -92.315 24.527  23.300  1.00 154.93 ? 506  PRO D N   1 
ATOM   11671 C CA  . PRO D 1 431 ? -93.645 25.128  23.216  1.00 150.85 ? 506  PRO D CA  1 
ATOM   11672 C C   . PRO D 1 431 ? -93.821 26.278  24.191  1.00 150.52 ? 506  PRO D C   1 
ATOM   11673 O O   . PRO D 1 431 ? -94.931 26.527  24.673  1.00 146.84 ? 506  PRO D O   1 
ATOM   11674 C CB  . PRO D 1 431 ? -94.550 23.948  23.570  1.00 151.87 ? 506  PRO D CB  1 
ATOM   11675 C CG  . PRO D 1 431 ? -93.740 23.238  24.671  1.00 154.85 ? 506  PRO D CG  1 
ATOM   11676 C CD  . PRO D 1 431 ? -92.257 23.610  24.454  1.00 160.09 ? 506  PRO D CD  1 
ATOM   11677 N N   . LEU D 1 432 ? -92.722 26.976  24.485  1.00 146.36 ? 507  LEU D N   1 
ATOM   11678 C CA  . LEU D 1 432 ? -92.714 28.075  25.443  1.00 158.38 ? 507  LEU D CA  1 
ATOM   11679 C C   . LEU D 1 432 ? -93.820 29.081  25.151  1.00 151.81 ? 507  LEU D C   1 
ATOM   11680 O O   . LEU D 1 432 ? -93.790 29.767  24.123  1.00 156.27 ? 507  LEU D O   1 
ATOM   11681 C CB  . LEU D 1 432 ? -91.348 28.768  25.435  1.00 163.69 ? 507  LEU D CB  1 
ATOM   11682 C CG  . LEU D 1 432 ? -90.144 28.054  26.060  1.00 162.99 ? 507  LEU D CG  1 
ATOM   11683 C CD1 . LEU D 1 432 ? -90.550 27.336  27.334  1.00 154.31 ? 507  LEU D CD1 1 
ATOM   11684 C CD2 . LEU D 1 432 ? -89.488 27.092  25.078  1.00 148.71 ? 507  LEU D CD2 1 
ATOM   11685 N N   . SER D 1 433 ? -94.803 29.165  26.050  1.00 149.97 ? 508  SER D N   1 
ATOM   11686 C CA  . SER D 1 433 ? -95.943 30.047  25.821  1.00 151.19 ? 508  SER D CA  1 
ATOM   11687 C C   . SER D 1 433 ? -95.519 31.511  25.805  1.00 147.50 ? 508  SER D C   1 
ATOM   11688 O O   . SER D 1 433 ? -96.012 32.297  24.988  1.00 142.42 ? 508  SER D O   1 
ATOM   11689 C CB  . SER D 1 433 ? -97.014 29.808  26.886  1.00 139.94 ? 508  SER D CB  1 
ATOM   11690 O OG  . SER D 1 433 ? -96.602 30.309  28.146  1.00 116.37 ? 508  SER D OG  1 
ATOM   11691 N N   . GLY D 1 434 ? -94.612 31.895  26.698  1.00 148.48 ? 509  GLY D N   1 
ATOM   11692 C CA  . GLY D 1 434 ? -94.108 33.253  26.726  1.00 146.42 ? 509  GLY D CA  1 
ATOM   11693 C C   . GLY D 1 434 ? -92.599 33.304  26.840  1.00 153.38 ? 509  GLY D C   1 
ATOM   11694 O O   . GLY D 1 434 ? -91.970 34.293  26.447  1.00 153.72 ? 509  GLY D O   1 
ATOM   11695 N N   . GLU D 1 435 ? -92.015 32.235  27.377  1.00 156.88 ? 510  GLU D N   1 
ATOM   11696 C CA  . GLU D 1 435 ? -90.570 32.164  27.551  1.00 158.57 ? 510  GLU D CA  1 
ATOM   11697 C C   . GLU D 1 435 ? -89.866 32.264  26.203  1.00 148.75 ? 510  GLU D C   1 
ATOM   11698 O O   . GLU D 1 435 ? -90.287 31.654  25.216  1.00 152.75 ? 510  GLU D O   1 
ATOM   11699 C CB  . GLU D 1 435 ? -90.198 30.858  28.259  1.00 154.72 ? 510  GLU D CB  1 
ATOM   11700 C CG  . GLU D 1 435 ? -88.710 30.549  28.315  1.00 157.69 ? 510  GLU D CG  1 
ATOM   11701 C CD  . GLU D 1 435 ? -87.908 31.648  28.980  1.00 165.49 ? 510  GLU D CD  1 
ATOM   11702 O OE1 . GLU D 1 435 ? -88.078 31.848  30.201  1.00 166.78 ? 510  GLU D OE1 1 
ATOM   11703 O OE2 . GLU D 1 435 ? -87.100 32.301  28.287  1.00 165.61 ? 510  GLU D OE2 1 
ATOM   11704 N N   . GLU D 1 436 ? -88.793 33.052  26.163  1.00 143.74 ? 511  GLU D N   1 
ATOM   11705 C CA  . GLU D 1 436 ? -88.066 33.256  24.917  1.00 136.71 ? 511  GLU D CA  1 
ATOM   11706 C C   . GLU D 1 436 ? -87.481 31.944  24.415  1.00 141.49 ? 511  GLU D C   1 
ATOM   11707 O O   . GLU D 1 436 ? -87.010 31.113  25.196  1.00 143.21 ? 511  GLU D O   1 
ATOM   11708 C CB  . GLU D 1 436 ? -86.948 34.288  25.097  1.00 136.83 ? 511  GLU D CB  1 
ATOM   11709 C CG  . GLU D 1 436 ? -87.398 35.670  25.562  1.00 141.70 ? 511  GLU D CG  1 
ATOM   11710 C CD  . GLU D 1 436 ? -87.773 35.715  27.031  1.00 153.01 ? 511  GLU D CD  1 
ATOM   11711 O OE1 . GLU D 1 436 ? -86.893 35.452  27.877  1.00 165.37 ? 511  GLU D OE1 1 
ATOM   11712 O OE2 . GLU D 1 436 ? -88.945 36.021  27.338  1.00 153.19 ? 511  GLU D OE2 1 
ATOM   11713 N N   . ALA D 1 437 ? -87.521 31.761  23.098  1.00 143.05 ? 512  ALA D N   1 
ATOM   11714 C CA  . ALA D 1 437 ? -86.964 30.562  22.493  1.00 129.50 ? 512  ALA D CA  1 
ATOM   11715 C C   . ALA D 1 437 ? -85.452 30.531  22.673  1.00 129.56 ? 512  ALA D C   1 
ATOM   11716 O O   . ALA D 1 437 ? -84.782 31.567  22.647  1.00 129.57 ? 512  ALA D O   1 
ATOM   11717 C CB  . ALA D 1 437 ? -87.325 30.495  21.010  1.00 122.26 ? 512  ALA D CB  1 
ATOM   11718 N N   . LEU D 1 438 ? -84.922 29.328  22.865  1.00 129.13 ? 513  LEU D N   1 
ATOM   11719 C CA  . LEU D 1 438 ? -83.496 29.152  23.088  1.00 116.86 ? 513  LEU D CA  1 
ATOM   11720 C C   . LEU D 1 438 ? -82.722 29.525  21.829  1.00 109.45 ? 513  LEU D C   1 
ATOM   11721 O O   . LEU D 1 438 ? -83.068 29.091  20.727  1.00 115.22 ? 513  LEU D O   1 
ATOM   11722 C CB  . LEU D 1 438 ? -83.217 27.703  23.484  1.00 101.64 ? 513  LEU D CB  1 
ATOM   11723 C CG  . LEU D 1 438 ? -82.044 27.381  24.406  1.00 104.28 ? 513  LEU D CG  1 
ATOM   11724 C CD1 . LEU D 1 438 ? -82.330 27.844  25.822  1.00 96.40  ? 513  LEU D CD1 1 
ATOM   11725 C CD2 . LEU D 1 438 ? -81.747 25.889  24.378  1.00 123.40 ? 513  LEU D CD2 1 
ATOM   11726 N N   . THR D 1 439 ? -81.681 30.339  21.987  1.00 100.06 ? 514  THR D N   1 
ATOM   11727 C CA  . THR D 1 439 ? -80.856 30.694  20.843  1.00 106.00 ? 514  THR D CA  1 
ATOM   11728 C C   . THR D 1 439 ? -80.121 29.464  20.319  1.00 110.94 ? 514  THR D C   1 
ATOM   11729 O O   . THR D 1 439 ? -79.880 28.498  21.048  1.00 120.20 ? 514  THR D O   1 
ATOM   11730 C CB  . THR D 1 439 ? -79.848 31.785  21.210  1.00 101.05 ? 514  THR D CB  1 
ATOM   11731 O OG1 . THR D 1 439 ? -78.713 31.192  21.850  1.00 114.48 ? 514  THR D OG1 1 
ATOM   11732 C CG2 . THR D 1 439 ? -80.480 32.796  22.154  1.00 109.84 ? 514  THR D CG2 1 
ATOM   11733 N N   . ASP D 1 440 ? -79.771 29.509  19.031  1.00 103.13 ? 515  ASP D N   1 
ATOM   11734 C CA  . ASP D 1 440 ? -79.104 28.372  18.404  1.00 113.47 ? 515  ASP D CA  1 
ATOM   11735 C C   . ASP D 1 440 ? -77.779 28.062  19.089  1.00 119.09 ? 515  ASP D C   1 
ATOM   11736 O O   . ASP D 1 440 ? -77.391 26.893  19.211  1.00 130.31 ? 515  ASP D O   1 
ATOM   11737 C CB  . ASP D 1 440 ? -78.892 28.646  16.916  1.00 125.96 ? 515  ASP D CB  1 
ATOM   11738 C CG  . ASP D 1 440 ? -80.199 28.815  16.163  1.00 138.43 ? 515  ASP D CG  1 
ATOM   11739 O OD1 . ASP D 1 440 ? -81.260 28.472  16.725  1.00 133.72 ? 515  ASP D OD1 1 
ATOM   11740 O OD2 . ASP D 1 440 ? -80.166 29.288  15.008  1.00 164.22 ? 515  ASP D OD2 1 
ATOM   11741 N N   . ARG D 1 441 ? -77.071 29.099  19.540  1.00 113.33 ? 516  ARG D N   1 
ATOM   11742 C CA  . ARG D 1 441 ? -75.873 28.890  20.347  1.00 115.46 ? 516  ARG D CA  1 
ATOM   11743 C C   . ARG D 1 441 ? -76.212 28.152  21.635  1.00 110.67 ? 516  ARG D C   1 
ATOM   11744 O O   . ARG D 1 441 ? -75.516 27.205  22.029  1.00 114.22 ? 516  ARG D O   1 
ATOM   11745 C CB  . ARG D 1 441 ? -75.225 30.241  20.651  1.00 106.80 ? 516  ARG D CB  1 
ATOM   11746 C CG  . ARG D 1 441 ? -73.909 30.178  21.398  1.00 112.80 ? 516  ARG D CG  1 
ATOM   11747 C CD  . ARG D 1 441 ? -73.416 31.586  21.689  1.00 113.47 ? 516  ARG D CD  1 
ATOM   11748 N NE  . ARG D 1 441 ? -73.475 32.437  20.505  1.00 119.50 ? 516  ARG D NE  1 
ATOM   11749 C CZ  . ARG D 1 441 ? -72.415 32.902  19.858  1.00 139.27 ? 516  ARG D CZ  1 
ATOM   11750 N NH1 . ARG D 1 441 ? -71.184 32.617  20.252  1.00 129.54 ? 516  ARG D NH1 1 
ATOM   11751 N NH2 . ARG D 1 441 ? -72.594 33.677  18.791  1.00 140.69 ? 516  ARG D NH2 1 
ATOM   11752 N N   . GLN D 1 442 ? -77.293 28.566  22.299  1.00 99.19  ? 517  GLN D N   1 
ATOM   11753 C CA  . GLN D 1 442 ? -77.730 27.883  23.507  1.00 100.08 ? 517  GLN D CA  1 
ATOM   11754 C C   . GLN D 1 442 ? -78.216 26.471  23.204  1.00 104.81 ? 517  GLN D C   1 
ATOM   11755 O O   . GLN D 1 442 ? -78.036 25.566  24.024  1.00 109.76 ? 517  GLN D O   1 
ATOM   11756 C CB  . GLN D 1 442 ? -78.825 28.699  24.193  1.00 104.47 ? 517  GLN D CB  1 
ATOM   11757 C CG  . GLN D 1 442 ? -78.347 30.008  24.795  1.00 103.96 ? 517  GLN D CG  1 
ATOM   11758 C CD  . GLN D 1 442 ? -79.490 30.938  25.147  1.00 108.99 ? 517  GLN D CD  1 
ATOM   11759 O OE1 . GLN D 1 442 ? -80.649 30.656  24.844  1.00 110.34 ? 517  GLN D OE1 1 
ATOM   11760 N NE2 . GLN D 1 442 ? -79.170 32.055  25.790  1.00 113.87 ? 517  GLN D NE2 1 
ATOM   11761 N N   . GLU D 1 443 ? -78.808 26.255  22.026  1.00 98.90  ? 518  GLU D N   1 
ATOM   11762 C CA  . GLU D 1 443 ? -79.230 24.910  21.646  1.00 103.79 ? 518  GLU D CA  1 
ATOM   11763 C C   . GLU D 1 443 ? -78.030 23.992  21.440  1.00 110.32 ? 518  GLU D C   1 
ATOM   11764 O O   . GLU D 1 443 ? -78.063 22.814  21.825  1.00 99.41  ? 518  GLU D O   1 
ATOM   11765 C CB  . GLU D 1 443 ? -80.086 24.972  20.380  1.00 113.64 ? 518  GLU D CB  1 
ATOM   11766 C CG  . GLU D 1 443 ? -81.445 25.626  20.580  1.00 108.91 ? 518  GLU D CG  1 
ATOM   11767 C CD  . GLU D 1 443 ? -82.198 25.811  19.278  1.00 114.83 ? 518  GLU D CD  1 
ATOM   11768 O OE1 . GLU D 1 443 ? -81.597 25.584  18.206  1.00 123.92 ? 518  GLU D OE1 1 
ATOM   11769 O OE2 . GLU D 1 443 ? -83.392 26.176  19.324  1.00 110.95 ? 518  GLU D OE2 1 
ATOM   11770 N N   . SER D 1 444 ? -76.958 24.513  20.836  1.00 113.25 ? 519  SER D N   1 
ATOM   11771 C CA  . SER D 1 444 ? -75.738 23.726  20.688  1.00 105.13 ? 519  SER D CA  1 
ATOM   11772 C C   . SER D 1 444 ? -75.100 23.439  22.043  1.00 95.54  ? 519  SER D C   1 
ATOM   11773 O O   . SER D 1 444 ? -74.631 22.320  22.295  1.00 103.84 ? 519  SER D O   1 
ATOM   11774 C CB  . SER D 1 444 ? -74.757 24.448  19.766  1.00 107.15 ? 519  SER D CB  1 
ATOM   11775 O OG  . SER D 1 444 ? -74.287 25.644  20.361  1.00 129.52 ? 519  SER D OG  1 
ATOM   11776 N N   . ALA D 1 445 ? -75.079 24.435  22.933  1.00 87.93  ? 520  ALA D N   1 
ATOM   11777 C CA  . ALA D 1 445 ? -74.600 24.192  24.291  1.00 87.88  ? 520  ALA D CA  1 
ATOM   11778 C C   . ALA D 1 445 ? -75.419 23.105  24.978  1.00 92.09  ? 520  ALA D C   1 
ATOM   11779 O O   . ALA D 1 445 ? -74.870 22.257  25.692  1.00 94.48  ? 520  ALA D O   1 
ATOM   11780 C CB  . ALA D 1 445 ? -74.638 25.487  25.102  1.00 79.77  ? 520  ALA D CB  1 
ATOM   11781 N N   . LEU D 1 446 ? -76.736 23.102  24.756  1.00 95.45  ? 521  LEU D N   1 
ATOM   11782 C CA  . LEU D 1 446 ? -77.600 22.125  25.410  1.00 92.72  ? 521  LEU D CA  1 
ATOM   11783 C C   . LEU D 1 446 ? -77.375 20.721  24.862  1.00 94.89  ? 521  LEU D C   1 
ATOM   11784 O O   . LEU D 1 446 ? -77.352 19.751  25.629  1.00 86.03  ? 521  LEU D O   1 
ATOM   11785 C CB  . LEU D 1 446 ? -79.065 22.532  25.259  1.00 89.29  ? 521  LEU D CB  1 
ATOM   11786 C CG  . LEU D 1 446 ? -80.082 21.669  26.012  1.00 80.29  ? 521  LEU D CG  1 
ATOM   11787 C CD1 . LEU D 1 446 ? -79.602 21.341  27.418  1.00 69.98  ? 521  LEU D CD1 1 
ATOM   11788 C CD2 . LEU D 1 446 ? -81.437 22.353  26.057  1.00 85.76  ? 521  LEU D CD2 1 
ATOM   11789 N N   . ILE D 1 447 ? -77.222 20.580  23.541  1.00 96.43  ? 522  ILE D N   1 
ATOM   11790 C CA  . ILE D 1 447 ? -76.952 19.248  23.001  1.00 87.40  ? 522  ILE D CA  1 
ATOM   11791 C C   . ILE D 1 447 ? -75.589 18.760  23.475  1.00 83.32  ? 522  ILE D C   1 
ATOM   11792 O O   . ILE D 1 447 ? -75.405 17.569  23.754  1.00 88.35  ? 522  ILE D O   1 
ATOM   11793 C CB  . ILE D 1 447 ? -77.064 19.217  21.461  1.00 80.28  ? 522  ILE D CB  1 
ATOM   11794 C CG1 . ILE D 1 447 ? -76.199 20.286  20.809  1.00 99.53  ? 522  ILE D CG1 1 
ATOM   11795 C CG2 . ILE D 1 447 ? -78.504 19.380  21.014  1.00 73.00  ? 522  ILE D CG2 1 
ATOM   11796 C CD1 . ILE D 1 447 ? -74.951 19.747  20.148  1.00 96.34  ? 522  ILE D CD1 1 
ATOM   11797 N N   . GLU D 1 448 ? -74.624 19.676  23.615  1.00 86.15  ? 523  GLU D N   1 
ATOM   11798 C CA  . GLU D 1 448 ? -73.320 19.298  24.154  1.00 85.40  ? 523  GLU D CA  1 
ATOM   11799 C C   . GLU D 1 448 ? -73.440 18.789  25.587  1.00 85.43  ? 523  GLU D C   1 
ATOM   11800 O O   . GLU D 1 448 ? -72.876 17.745  25.940  1.00 87.65  ? 523  GLU D O   1 
ATOM   11801 C CB  . GLU D 1 448 ? -72.363 20.491  24.082  1.00 80.12  ? 523  GLU D CB  1 
ATOM   11802 C CG  . GLU D 1 448 ? -71.074 20.325  24.880  1.00 91.51  ? 523  GLU D CG  1 
ATOM   11803 C CD  . GLU D 1 448 ? -70.167 19.224  24.344  1.00 102.12 ? 523  GLU D CD  1 
ATOM   11804 O OE1 . GLU D 1 448 ? -70.427 18.696  23.243  1.00 99.51  ? 523  GLU D OE1 1 
ATOM   11805 O OE2 . GLU D 1 448 ? -69.186 18.884  25.038  1.00 99.14  ? 523  GLU D OE2 1 
ATOM   11806 N N   . ILE D 1 449 ? -74.170 19.523  26.430  1.00 91.93  ? 524  ILE D N   1 
ATOM   11807 C CA  . ILE D 1 449 ? -74.327 19.125  27.829  1.00 78.76  ? 524  ILE D CA  1 
ATOM   11808 C C   . ILE D 1 449 ? -75.054 17.790  27.929  1.00 69.24  ? 524  ILE D C   1 
ATOM   11809 O O   . ILE D 1 449 ? -74.681 16.919  28.728  1.00 63.06  ? 524  ILE D O   1 
ATOM   11810 C CB  . ILE D 1 449 ? -75.057 20.228  28.618  1.00 66.60  ? 524  ILE D CB  1 
ATOM   11811 C CG1 . ILE D 1 449 ? -74.209 21.501  28.657  1.00 75.14  ? 524  ILE D CG1 1 
ATOM   11812 C CG2 . ILE D 1 449 ? -75.395 19.752  30.023  1.00 57.19  ? 524  ILE D CG2 1 
ATOM   11813 C CD1 . ILE D 1 449 ? -74.909 22.685  29.273  1.00 78.86  ? 524  ILE D CD1 1 
ATOM   11814 N N   . MET D 1 450 ? -76.107 17.614  27.128  1.00 67.11  ? 525  MET D N   1 
ATOM   11815 C CA  . MET D 1 450 ? -76.848 16.359  27.128  1.00 75.60  ? 525  MET D CA  1 
ATOM   11816 C C   . MET D 1 450 ? -75.960 15.198  26.702  1.00 72.19  ? 525  MET D C   1 
ATOM   11817 O O   . MET D 1 450 ? -76.005 14.116  27.302  1.00 69.80  ? 525  MET D O   1 
ATOM   11818 C CB  . MET D 1 450 ? -78.064 16.486  26.210  1.00 74.25  ? 525  MET D CB  1 
ATOM   11819 C CG  . MET D 1 450 ? -78.767 15.184  25.894  1.00 74.61  ? 525  MET D CG  1 
ATOM   11820 S SD  . MET D 1 450 ? -80.254 15.467  24.916  1.00 84.37  ? 525  MET D SD  1 
ATOM   11821 C CE  . MET D 1 450 ? -79.569 15.600  23.265  1.00 95.18  ? 525  MET D CE  1 
ATOM   11822 N N   . LEU D 1 451 ? -75.131 15.410  25.676  1.00 75.04  ? 526  LEU D N   1 
ATOM   11823 C CA  . LEU D 1 451 ? -74.200 14.374  25.244  1.00 74.20  ? 526  LEU D CA  1 
ATOM   11824 C C   . LEU D 1 451 ? -73.203 14.033  26.344  1.00 71.47  ? 526  LEU D C   1 
ATOM   11825 O O   . LEU D 1 451 ? -72.873 12.860  26.550  1.00 78.18  ? 526  LEU D O   1 
ATOM   11826 C CB  . LEU D 1 451 ? -73.471 14.828  23.980  1.00 64.77  ? 526  LEU D CB  1 
ATOM   11827 C CG  . LEU D 1 451 ? -72.217 14.045  23.590  1.00 82.94  ? 526  LEU D CG  1 
ATOM   11828 C CD1 . LEU D 1 451 ? -72.583 12.719  22.942  1.00 88.59  ? 526  LEU D CD1 1 
ATOM   11829 C CD2 . LEU D 1 451 ? -71.336 14.874  22.671  1.00 95.84  ? 526  LEU D CD2 1 
ATOM   11830 N N   . CYS D 1 452 ? -72.708 15.046  27.059  1.00 68.15  ? 527  CYS D N   1 
ATOM   11831 C CA  . CYS D 1 452 ? -71.752 14.785  28.132  1.00 69.80  ? 527  CYS D CA  1 
ATOM   11832 C C   . CYS D 1 452 ? -72.388 13.977  29.256  1.00 66.99  ? 527  CYS D C   1 
ATOM   11833 O O   . CYS D 1 452 ? -71.780 13.029  29.772  1.00 69.85  ? 527  CYS D O   1 
ATOM   11834 C CB  . CYS D 1 452 ? -71.185 16.097  28.671  1.00 65.92  ? 527  CYS D CB  1 
ATOM   11835 S SG  . CYS D 1 452 ? -70.160 17.007  27.498  1.00 76.73  ? 527  CYS D SG  1 
ATOM   11836 N N   . THR D 1 453 ? -73.607 14.344  29.657  1.00 61.39  ? 528  THR D N   1 
ATOM   11837 C CA  . THR D 1 453 ? -74.289 13.577  30.696  1.00 69.14  ? 528  THR D CA  1 
ATOM   11838 C C   . THR D 1 453 ? -74.552 12.147  30.238  1.00 71.92  ? 528  THR D C   1 
ATOM   11839 O O   . THR D 1 453 ? -74.388 11.198  31.015  1.00 71.84  ? 528  THR D O   1 
ATOM   11840 C CB  . THR D 1 453 ? -75.595 14.264  31.101  1.00 67.74  ? 528  THR D CB  1 
ATOM   11841 O OG1 . THR D 1 453 ? -76.491 14.303  29.983  1.00 72.89  ? 528  THR D OG1 1 
ATOM   11842 C CG2 . THR D 1 453 ? -75.323 15.682  31.589  1.00 63.85  ? 528  THR D CG2 1 
ATOM   11843 N N   . ILE D 1 454 ? -74.939 11.971  28.971  1.00 73.35  ? 529  ILE D N   1 
ATOM   11844 C CA  . ILE D 1 454 ? -75.176 10.632  28.439  1.00 74.66  ? 529  ILE D CA  1 
ATOM   11845 C C   . ILE D 1 454 ? -73.896 9.810   28.472  1.00 74.12  ? 529  ILE D C   1 
ATOM   11846 O O   . ILE D 1 454 ? -73.907 8.627   28.835  1.00 78.96  ? 529  ILE D O   1 
ATOM   11847 C CB  . ILE D 1 454 ? -75.750 10.725  27.015  1.00 70.06  ? 529  ILE D CB  1 
ATOM   11848 C CG1 . ILE D 1 454 ? -77.185 11.245  27.062  1.00 76.89  ? 529  ILE D CG1 1 
ATOM   11849 C CG2 . ILE D 1 454 ? -75.687 9.375   26.317  1.00 76.17  ? 529  ILE D CG2 1 
ATOM   11850 C CD1 . ILE D 1 454 ? -77.683 11.726  25.737  1.00 73.08  ? 529  ILE D CD1 1 
ATOM   11851 N N   . ARG D 1 455 ? -72.773 10.424  28.096  1.00 70.07  ? 530  ARG D N   1 
ATOM   11852 C CA  . ARG D 1 455 ? -71.500 9.714   28.114  1.00 77.64  ? 530  ARG D CA  1 
ATOM   11853 C C   . ARG D 1 455 ? -71.124 9.304   29.530  1.00 78.75  ? 530  ARG D C   1 
ATOM   11854 O O   . ARG D 1 455 ? -70.752 8.151   29.777  1.00 90.30  ? 530  ARG D O   1 
ATOM   11855 C CB  . ARG D 1 455 ? -70.401 10.583  27.503  1.00 84.10  ? 530  ARG D CB  1 
ATOM   11856 C CG  . ARG D 1 455 ? -69.016 9.962   27.605  1.00 94.60  ? 530  ARG D CG  1 
ATOM   11857 C CD  . ARG D 1 455 ? -67.929 10.873  27.051  1.00 105.39 ? 530  ARG D CD  1 
ATOM   11858 N NE  . ARG D 1 455 ? -68.238 11.376  25.718  1.00 115.63 ? 530  ARG D NE  1 
ATOM   11859 C CZ  . ARG D 1 455 ? -68.479 12.650  25.440  1.00 107.95 ? 530  ARG D CZ  1 
ATOM   11860 N NH1 . ARG D 1 455 ? -68.450 13.580  26.382  1.00 93.40  ? 530  ARG D NH1 1 
ATOM   11861 N NH2 . ARG D 1 455 ? -68.753 13.001  24.187  1.00 98.56  ? 530  ARG D NH2 1 
ATOM   11862 N N   . GLN D 1 456 ? -71.213 10.241  30.478  1.00 69.62  ? 531  GLN D N   1 
ATOM   11863 C CA  . GLN D 1 456 ? -70.808 9.925   31.844  1.00 71.00  ? 531  GLN D CA  1 
ATOM   11864 C C   . GLN D 1 456 ? -71.746 8.916   32.495  1.00 76.27  ? 531  GLN D C   1 
ATOM   11865 O O   . GLN D 1 456 ? -71.332 8.188   33.405  1.00 76.19  ? 531  GLN D O   1 
ATOM   11866 C CB  . GLN D 1 456 ? -70.720 11.199  32.685  1.00 65.93  ? 531  GLN D CB  1 
ATOM   11867 C CG  . GLN D 1 456 ? -69.869 11.044  33.938  1.00 60.95  ? 531  GLN D CG  1 
ATOM   11868 C CD  . GLN D 1 456 ? -69.122 12.312  34.298  1.00 57.51  ? 531  GLN D CD  1 
ATOM   11869 O OE1 . GLN D 1 456 ? -69.164 13.298  33.562  1.00 62.72  ? 531  GLN D OE1 1 
ATOM   11870 N NE2 . GLN D 1 456 ? -68.432 12.294  35.431  1.00 51.91  ? 531  GLN D NE2 1 
ATOM   11871 N N   . ALA D 1 457 ? -73.000 8.847   32.043  1.00 79.57  ? 532  ALA D N   1 
ATOM   11872 C CA  . ALA D 1 457 ? -73.910 7.837   32.570  1.00 76.31  ? 532  ALA D CA  1 
ATOM   11873 C C   . ALA D 1 457 ? -73.631 6.465   31.966  1.00 78.93  ? 532  ALA D C   1 
ATOM   11874 O O   . ALA D 1 457 ? -73.562 5.465   32.688  1.00 89.65  ? 532  ALA D O   1 
ATOM   11875 C CB  . ALA D 1 457 ? -75.358 8.250   32.312  1.00 77.17  ? 532  ALA D CB  1 
ATOM   11876 N N   . ALA D 1 458 ? -73.463 6.403   30.642  1.00 72.80  ? 533  ALA D N   1 
ATOM   11877 C CA  . ALA D 1 458 ? -73.230 5.122   29.981  1.00 83.41  ? 533  ALA D CA  1 
ATOM   11878 C C   . ALA D 1 458 ? -71.868 4.548   30.347  1.00 86.77  ? 533  ALA D C   1 
ATOM   11879 O O   . ALA D 1 458 ? -71.745 3.345   30.611  1.00 88.67  ? 533  ALA D O   1 
ATOM   11880 C CB  . ALA D 1 458 ? -73.354 5.285   28.468  1.00 87.16  ? 533  ALA D CB  1 
ATOM   11881 N N   . GLU D 1 459 ? -70.835 5.384   30.357  1.00 82.54  ? 534  GLU D N   1 
ATOM   11882 C CA  . GLU D 1 459 ? -69.504 4.996   30.817  1.00 81.47  ? 534  GLU D CA  1 
ATOM   11883 C C   . GLU D 1 459 ? -69.305 5.634   32.187  1.00 94.54  ? 534  GLU D C   1 
ATOM   11884 O O   . GLU D 1 459 ? -69.053 6.837   32.291  1.00 123.08 ? 534  GLU D O   1 
ATOM   11885 C CB  . GLU D 1 459 ? -68.425 5.445   29.838  1.00 84.55  ? 534  GLU D CB  1 
ATOM   11886 C CG  . GLU D 1 459 ? -68.889 5.614   28.405  1.00 96.87  ? 534  GLU D CG  1 
ATOM   11887 C CD  . GLU D 1 459 ? -67.782 6.125   27.505  1.00 101.28 ? 534  GLU D CD  1 
ATOM   11888 O OE1 . GLU D 1 459 ? -67.166 7.155   27.855  1.00 88.69  ? 534  GLU D OE1 1 
ATOM   11889 O OE2 . GLU D 1 459 ? -67.533 5.507   26.448  1.00 102.20 ? 534  GLU D OE2 1 
ATOM   11890 N N   . CYS D 1 460 ? -69.423 4.826   33.240  1.00 78.94  ? 535  CYS D N   1 
ATOM   11891 C CA  . CYS D 1 460 ? -69.369 5.323   34.614  1.00 77.48  ? 535  CYS D CA  1 
ATOM   11892 C C   . CYS D 1 460 ? -67.926 5.650   35.012  1.00 90.16  ? 535  CYS D C   1 
ATOM   11893 O O   . CYS D 1 460 ? -67.324 5.027   35.887  1.00 106.73 ? 535  CYS D O   1 
ATOM   11894 C CB  . CYS D 1 460 ? -69.997 4.303   35.557  1.00 75.45  ? 535  CYS D CB  1 
ATOM   11895 S SG  . CYS D 1 460 ? -70.040 4.781   37.302  1.00 121.56 ? 535  CYS D SG  1 
ATOM   11896 N N   . HIS D 1 461 ? -67.368 6.656   34.340  1.00 86.65  ? 536  HIS D N   1 
ATOM   11897 C CA  . HIS D 1 461 ? -65.995 7.067   34.587  1.00 90.26  ? 536  HIS D CA  1 
ATOM   11898 C C   . HIS D 1 461 ? -65.855 8.538   34.237  1.00 84.84  ? 536  HIS D C   1 
ATOM   11899 O O   . HIS D 1 461 ? -66.521 9.023   33.315  1.00 87.35  ? 536  HIS D O   1 
ATOM   11900 C CB  . HIS D 1 461 ? -64.992 6.231   33.776  1.00 99.29  ? 536  HIS D CB  1 
ATOM   11901 C CG  . HIS D 1 461 ? -64.830 6.677   32.357  1.00 107.14 ? 536  HIS D CG  1 
ATOM   11902 N ND1 . HIS D 1 461 ? -63.658 7.225   31.884  1.00 119.73 ? 536  HIS D ND1 1 
ATOM   11903 C CD2 . HIS D 1 461 ? -65.685 6.650   31.308  1.00 125.53 ? 536  HIS D CD2 1 
ATOM   11904 C CE1 . HIS D 1 461 ? -63.798 7.519   30.604  1.00 122.75 ? 536  HIS D CE1 1 
ATOM   11905 N NE2 . HIS D 1 461 ? -65.018 7.180   30.229  1.00 138.05 ? 536  HIS D NE2 1 
ATOM   11906 N N   . PRO D 1 462 ? -65.004 9.268   34.945  1.00 81.01  ? 537  PRO D N   1 
ATOM   11907 C CA  . PRO D 1 462 ? -64.841 10.698  34.675  1.00 83.20  ? 537  PRO D CA  1 
ATOM   11908 C C   . PRO D 1 462 ? -64.102 10.917  33.368  1.00 83.68  ? 537  PRO D C   1 
ATOM   11909 O O   . PRO D 1 462 ? -63.498 9.981   32.821  1.00 91.43  ? 537  PRO D O   1 
ATOM   11910 C CB  . PRO D 1 462 ? -64.010 11.192  35.873  1.00 79.90  ? 537  PRO D CB  1 
ATOM   11911 C CG  . PRO D 1 462 ? -64.059 10.084  36.888  1.00 89.19  ? 537  PRO D CG  1 
ATOM   11912 C CD  . PRO D 1 462 ? -64.221 8.828   36.110  1.00 93.69  ? 537  PRO D CD  1 
ATOM   11913 N N   . PRO D 1 463 ? -64.133 12.134  32.830  1.00 76.61  ? 538  PRO D N   1 
ATOM   11914 C CA  . PRO D 1 463 ? -63.336 12.433  31.638  1.00 86.04  ? 538  PRO D CA  1 
ATOM   11915 C C   . PRO D 1 463 ? -61.845 12.414  31.945  1.00 81.27  ? 538  PRO D C   1 
ATOM   11916 O O   . PRO D 1 463 ? -61.418 12.450  33.101  1.00 86.60  ? 538  PRO D O   1 
ATOM   11917 C CB  . PRO D 1 463 ? -63.811 13.836  31.242  1.00 87.13  ? 538  PRO D CB  1 
ATOM   11918 C CG  . PRO D 1 463 ? -64.279 14.432  32.536  1.00 79.21  ? 538  PRO D CG  1 
ATOM   11919 C CD  . PRO D 1 463 ? -64.955 13.287  33.234  1.00 77.63  ? 538  PRO D CD  1 
ATOM   11920 N N   . VAL D 1 464 ? -61.047 12.350  30.874  1.00 85.17  ? 539  VAL D N   1 
ATOM   11921 C CA  . VAL D 1 464 ? -59.601 12.250  31.028  1.00 79.15  ? 539  VAL D CA  1 
ATOM   11922 C C   . VAL D 1 464 ? -59.070 13.500  31.719  1.00 81.64  ? 539  VAL D C   1 
ATOM   11923 O O   . VAL D 1 464 ? -59.531 14.621  31.467  1.00 86.48  ? 539  VAL D O   1 
ATOM   11924 C CB  . VAL D 1 464 ? -58.930 12.021  29.662  1.00 78.33  ? 539  VAL D CB  1 
ATOM   11925 C CG1 . VAL D 1 464 ? -59.293 13.127  28.696  1.00 77.35  ? 539  VAL D CG1 1 
ATOM   11926 C CG2 . VAL D 1 464 ? -57.419 11.910  29.811  1.00 84.72  ? 539  VAL D CG2 1 
ATOM   11927 N N   . GLY D 1 465 ? -58.098 13.307  32.612  1.00 80.56  ? 540  GLY D N   1 
ATOM   11928 C CA  . GLY D 1 465 ? -57.644 14.350  33.500  1.00 84.08  ? 540  GLY D CA  1 
ATOM   11929 C C   . GLY D 1 465 ? -58.368 14.388  34.827  1.00 80.31  ? 540  GLY D C   1 
ATOM   11930 O O   . GLY D 1 465 ? -57.852 14.974  35.786  1.00 82.37  ? 540  GLY D O   1 
ATOM   11931 N N   . ARG D 1 466 ? -59.553 13.781  34.903  1.00 82.63  ? 541  ARG D N   1 
ATOM   11932 C CA  . ARG D 1 466 ? -60.282 13.615  36.149  1.00 89.72  ? 541  ARG D CA  1 
ATOM   11933 C C   . ARG D 1 466 ? -60.393 12.164  36.591  1.00 87.08  ? 541  ARG D C   1 
ATOM   11934 O O   . ARG D 1 466 ? -60.538 11.911  37.791  1.00 71.81  ? 541  ARG D O   1 
ATOM   11935 C CB  . ARG D 1 466 ? -61.700 14.194  36.025  1.00 80.25  ? 541  ARG D CB  1 
ATOM   11936 C CG  . ARG D 1 466 ? -61.758 15.641  35.571  1.00 80.50  ? 541  ARG D CG  1 
ATOM   11937 C CD  . ARG D 1 466 ? -61.160 16.583  36.605  1.00 76.12  ? 541  ARG D CD  1 
ATOM   11938 N NE  . ARG D 1 466 ? -61.406 17.981  36.269  1.00 78.12  ? 541  ARG D NE  1 
ATOM   11939 C CZ  . ARG D 1 466 ? -62.588 18.577  36.354  1.00 80.87  ? 541  ARG D CZ  1 
ATOM   11940 N NH1 . ARG D 1 466 ? -63.661 17.931  36.784  1.00 68.21  ? 541  ARG D NH1 1 
ATOM   11941 N NH2 . ARG D 1 466 ? -62.697 19.855  36.002  1.00 76.74  ? 541  ARG D NH2 1 
ATOM   11942 N N   . GLY D 1 467 ? -60.330 11.212  35.661  1.00 105.18 ? 542  GLY D N   1 
ATOM   11943 C CA  . GLY D 1 467 ? -60.527 9.823   36.002  1.00 100.83 ? 542  GLY D CA  1 
ATOM   11944 C C   . GLY D 1 467 ? -59.245 9.108   36.378  1.00 105.07 ? 542  GLY D C   1 
ATOM   11945 O O   . GLY D 1 467 ? -58.137 9.576   36.122  1.00 99.37  ? 542  GLY D O   1 
ATOM   11946 N N   . THR D 1 468 ? -59.417 7.946   37.005  1.00 126.69 ? 543  THR D N   1 
ATOM   11947 C CA  . THR D 1 468 ? -58.291 7.083   37.331  1.00 126.49 ? 543  THR D CA  1 
ATOM   11948 C C   . THR D 1 468 ? -58.093 6.043   36.233  1.00 112.21 ? 543  THR D C   1 
ATOM   11949 O O   . THR D 1 468 ? -57.890 6.407   35.071  1.00 110.08 ? 543  THR D O   1 
ATOM   11950 C CB  . THR D 1 468 ? -58.501 6.424   38.694  1.00 134.73 ? 543  THR D CB  1 
ATOM   11951 O OG1 . THR D 1 468 ? -59.548 5.451   38.599  1.00 151.46 ? 543  THR D OG1 1 
ATOM   11952 C CG2 . THR D 1 468 ? -58.871 7.472   39.732  1.00 102.61 ? 543  THR D CG2 1 
ATOM   11953 N N   . GLY D 1 469 ? -58.156 4.757   36.571  1.00 124.76 ? 544  GLY D N   1 
ATOM   11954 C CA  . GLY D 1 469 ? -57.824 3.742   35.586  1.00 143.61 ? 544  GLY D CA  1 
ATOM   11955 C C   . GLY D 1 469 ? -58.808 2.603   35.412  1.00 141.48 ? 544  GLY D C   1 
ATOM   11956 O O   . GLY D 1 469 ? -58.599 1.521   35.966  1.00 152.34 ? 544  GLY D O   1 
ATOM   11957 N N   . LYS D 1 470 ? -59.860 2.831   34.626  1.00 130.48 ? 545  LYS D N   1 
ATOM   11958 C CA  . LYS D 1 470 ? -60.880 1.829   34.291  1.00 146.58 ? 545  LYS D CA  1 
ATOM   11959 C C   . LYS D 1 470 ? -61.307 1.027   35.519  1.00 144.60 ? 545  LYS D C   1 
ATOM   11960 O O   . LYS D 1 470 ? -61.172 -0.195  35.571  1.00 145.79 ? 545  LYS D O   1 
ATOM   11961 C CB  . LYS D 1 470 ? -60.388 0.875   33.196  1.00 159.78 ? 545  LYS D CB  1 
ATOM   11962 C CG  . LYS D 1 470 ? -59.905 1.530   31.922  1.00 164.00 ? 545  LYS D CG  1 
ATOM   11963 C CD  . LYS D 1 470 ? -59.154 0.523   31.060  1.00 151.47 ? 545  LYS D CD  1 
ATOM   11964 C CE  . LYS D 1 470 ? -57.947 -0.058  31.781  1.00 145.43 ? 545  LYS D CE  1 
ATOM   11965 N NZ  . LYS D 1 470 ? -57.107 0.983   32.429  1.00 151.00 ? 545  LYS D NZ  1 
ATOM   11966 N N   . ARG D 1 471 ? -61.829 1.735   36.516  1.00 136.52 ? 546  ARG D N   1 
ATOM   11967 C CA  . ARG D 1 471 ? -62.107 1.088   37.789  1.00 115.19 ? 546  ARG D CA  1 
ATOM   11968 C C   . ARG D 1 471 ? -63.243 0.089   37.661  1.00 110.19 ? 546  ARG D C   1 
ATOM   11969 O O   . ARG D 1 471 ? -64.244 0.336   36.984  1.00 114.97 ? 546  ARG D O   1 
ATOM   11970 C CB  . ARG D 1 471 ? -62.438 2.108   38.881  1.00 114.50 ? 546  ARG D CB  1 
ATOM   11971 C CG  . ARG D 1 471 ? -62.878 1.439   40.185  1.00 111.41 ? 546  ARG D CG  1 
ATOM   11972 C CD  . ARG D 1 471 ? -63.666 2.339   41.125  1.00 109.41 ? 546  ARG D CD  1 
ATOM   11973 N NE  . ARG D 1 471 ? -64.626 3.201   40.450  1.00 93.23  ? 546  ARG D NE  1 
ATOM   11974 C CZ  . ARG D 1 471 ? -65.929 2.964   40.384  1.00 92.17  ? 546  ARG D CZ  1 
ATOM   11975 N NH1 . ARG D 1 471 ? -66.462 1.879   40.920  1.00 85.37  ? 546  ARG D NH1 1 
ATOM   11976 N NH2 . ARG D 1 471 ? -66.716 3.836   39.759  1.00 101.52 ? 546  ARG D NH2 1 
ATOM   11977 N N   . VAL D 1 472 ? -63.063 -1.064  38.303  1.00 97.42  ? 547  VAL D N   1 
ATOM   11978 C CA  . VAL D 1 472 ? -64.162 -2.000  38.462  1.00 97.12  ? 547  VAL D CA  1 
ATOM   11979 C C   . VAL D 1 472 ? -65.315 -1.284  39.145  1.00 92.34  ? 547  VAL D C   1 
ATOM   11980 O O   . VAL D 1 472 ? -65.182 -0.799  40.276  1.00 87.95  ? 547  VAL D O   1 
ATOM   11981 C CB  . VAL D 1 472 ? -63.713 -3.220  39.259  1.00 90.30  ? 547  VAL D CB  1 
ATOM   11982 C CG1 . VAL D 1 472 ? -64.866 -4.199  39.391  1.00 91.37  ? 547  VAL D CG1 1 
ATOM   11983 C CG2 . VAL D 1 472 ? -62.515 -3.865  38.582  1.00 111.74 ? 547  VAL D CG2 1 
ATOM   11984 N N   . LEU D 1 473 ? -66.442 -1.191  38.452  1.00 90.07  ? 548  LEU D N   1 
ATOM   11985 C CA  . LEU D 1 473 ? -67.602 -0.517  39.007  1.00 88.25  ? 548  LEU D CA  1 
ATOM   11986 C C   . LEU D 1 473 ? -68.182 -1.315  40.168  1.00 87.78  ? 548  LEU D C   1 
ATOM   11987 O O   . LEU D 1 473 ? -68.080 -2.544  40.219  1.00 86.07  ? 548  LEU D O   1 
ATOM   11988 C CB  . LEU D 1 473 ? -68.665 -0.317  37.926  1.00 91.71  ? 548  LEU D CB  1 
ATOM   11989 C CG  . LEU D 1 473 ? -68.173 0.449   36.698  1.00 72.98  ? 548  LEU D CG  1 
ATOM   11990 C CD1 . LEU D 1 473 ? -69.325 0.746   35.755  1.00 81.91  ? 548  LEU D CD1 1 
ATOM   11991 C CD2 . LEU D 1 473 ? -67.448 1.726   37.101  1.00 68.80  ? 548  LEU D CD2 1 
ATOM   11992 N N   . THR D 1 474 ? -68.790 -0.604  41.113  1.00 90.70  ? 549  THR D N   1 
ATOM   11993 C CA  . THR D 1 474 ? -69.471 -1.282  42.202  1.00 85.49  ? 549  THR D CA  1 
ATOM   11994 C C   . THR D 1 474 ? -70.744 -1.934  41.671  1.00 86.55  ? 549  THR D C   1 
ATOM   11995 O O   . THR D 1 474 ? -71.265 -1.565  40.615  1.00 89.19  ? 549  THR D O   1 
ATOM   11996 C CB  . THR D 1 474 ? -69.799 -0.304  43.332  1.00 75.28  ? 549  THR D CB  1 
ATOM   11997 O OG1 . THR D 1 474 ? -68.671 0.545   43.566  1.00 90.88  ? 549  THR D OG1 1 
ATOM   11998 C CG2 . THR D 1 474 ? -70.083 -1.064  44.617  1.00 74.60  ? 549  THR D CG2 1 
ATOM   11999 N N   . ALA D 1 475 ? -71.228 -2.941  42.402  1.00 85.19  ? 550  ALA D N   1 
ATOM   12000 C CA  . ALA D 1 475 ? -72.483 -3.589  42.036  1.00 82.69  ? 550  ALA D CA  1 
ATOM   12001 C C   . ALA D 1 475 ? -73.600 -2.565  41.880  1.00 83.64  ? 550  ALA D C   1 
ATOM   12002 O O   . ALA D 1 475 ? -74.342 -2.577  40.888  1.00 87.08  ? 550  ALA D O   1 
ATOM   12003 C CB  . ALA D 1 475 ? -72.851 -4.638  43.084  1.00 101.01 ? 550  ALA D CB  1 
ATOM   12004 N N   . LYS D 1 476 ? -73.723 -1.656  42.852  1.00 91.67  ? 551  LYS D N   1 
ATOM   12005 C CA  . LYS D 1 476 ? -74.699 -0.579  42.734  1.00 95.85  ? 551  LYS D CA  1 
ATOM   12006 C C   . LYS D 1 476 ? -74.417 0.286   41.514  1.00 79.60  ? 551  LYS D C   1 
ATOM   12007 O O   . LYS D 1 476 ? -75.347 0.720   40.825  1.00 96.11  ? 551  LYS D O   1 
ATOM   12008 C CB  . LYS D 1 476 ? -74.709 0.271   44.005  1.00 101.78 ? 551  LYS D CB  1 
ATOM   12009 C CG  . LYS D 1 476 ? -75.814 1.315   44.029  1.00 113.95 ? 551  LYS D CG  1 
ATOM   12010 C CD  . LYS D 1 476 ? -77.180 0.666   43.855  1.00 140.60 ? 551  LYS D CD  1 
ATOM   12011 C CE  . LYS D 1 476 ? -78.272 1.705   43.661  1.00 162.28 ? 551  LYS D CE  1 
ATOM   12012 N NZ  . LYS D 1 476 ? -78.160 2.391   42.343  1.00 180.46 ? 551  LYS D NZ  1 
ATOM   12013 N N   . GLU D 1 477 ? -73.140 0.538   41.222  1.00 81.72  ? 552  GLU D N   1 
ATOM   12014 C CA  . GLU D 1 477 ? -72.805 1.315   40.033  1.00 85.86  ? 552  GLU D CA  1 
ATOM   12015 C C   . GLU D 1 477 ? -73.131 0.559   38.754  1.00 82.03  ? 552  GLU D C   1 
ATOM   12016 O O   . GLU D 1 477 ? -73.572 1.162   37.772  1.00 85.67  ? 552  GLU D O   1 
ATOM   12017 C CB  . GLU D 1 477 ? -71.336 1.712   40.040  1.00 77.37  ? 552  GLU D CB  1 
ATOM   12018 C CG  . GLU D 1 477 ? -70.969 2.685   41.119  1.00 90.94  ? 552  GLU D CG  1 
ATOM   12019 C CD  . GLU D 1 477 ? -69.518 3.052   41.042  1.00 76.01  ? 552  GLU D CD  1 
ATOM   12020 O OE1 . GLU D 1 477 ? -68.829 2.523   40.147  1.00 93.14  ? 552  GLU D OE1 1 
ATOM   12021 O OE2 . GLU D 1 477 ? -69.077 3.905   41.828  1.00 76.63  ? 552  GLU D OE2 1 
ATOM   12022 N N   . LYS D 1 478 ? -72.906 -0.756  38.734  1.00 89.64  ? 553  LYS D N   1 
ATOM   12023 C CA  . LYS D 1 478 ? -73.272 -1.534  37.556  1.00 83.00  ? 553  LYS D CA  1 
ATOM   12024 C C   . LYS D 1 478 ? -74.777 -1.484  37.321  1.00 84.30  ? 553  LYS D C   1 
ATOM   12025 O O   . LYS D 1 478 ? -75.231 -1.315  36.182  1.00 86.41  ? 553  LYS D O   1 
ATOM   12026 C CB  . LYS D 1 478 ? -72.787 -2.976  37.710  1.00 86.90  ? 553  LYS D CB  1 
ATOM   12027 C CG  . LYS D 1 478 ? -71.274 -3.125  37.657  1.00 73.04  ? 553  LYS D CG  1 
ATOM   12028 C CD  . LYS D 1 478 ? -70.847 -4.553  37.954  1.00 70.34  ? 553  LYS D CD  1 
ATOM   12029 C CE  . LYS D 1 478 ? -69.462 -4.851  37.401  1.00 102.10 ? 553  LYS D CE  1 
ATOM   12030 N NZ  . LYS D 1 478 ? -68.408 -3.996  38.015  1.00 111.31 ? 553  LYS D NZ  1 
ATOM   12031 N N   . LYS D 1 479 ? -75.565 -1.595  38.395  1.00 92.40  ? 554  LYS D N   1 
ATOM   12032 C CA  . LYS D 1 479 ? -77.018 -1.517  38.264  1.00 85.17  ? 554  LYS D CA  1 
ATOM   12033 C C   . LYS D 1 479 ? -77.467 -0.131  37.809  1.00 87.41  ? 554  LYS D C   1 
ATOM   12034 O O   . LYS D 1 479 ? -78.347 -0.010  36.947  1.00 93.80  ? 554  LYS D O   1 
ATOM   12035 C CB  . LYS D 1 479 ? -77.680 -1.889  39.591  1.00 81.34  ? 554  LYS D CB  1 
ATOM   12036 C CG  . LYS D 1 479 ? -79.190 -1.709  39.619  1.00 101.54 ? 554  LYS D CG  1 
ATOM   12037 C CD  . LYS D 1 479 ? -79.916 -2.895  39.001  1.00 120.51 ? 554  LYS D CD  1 
ATOM   12038 C CE  . LYS D 1 479 ? -81.321 -2.504  38.572  1.00 115.56 ? 554  LYS D CE  1 
ATOM   12039 N NZ  . LYS D 1 479 ? -81.737 -3.161  37.302  1.00 110.42 ? 554  LYS D NZ  1 
ATOM   12040 N N   . THR D 1 480 ? -76.884 0.926   38.385  1.00 88.22  ? 555  THR D N   1 
ATOM   12041 C CA  . THR D 1 480 ? -77.221 2.287   37.972  1.00 92.46  ? 555  THR D CA  1 
ATOM   12042 C C   . THR D 1 480 ? -76.864 2.519   36.511  1.00 98.53  ? 555  THR D C   1 
ATOM   12043 O O   . THR D 1 480 ? -77.620 3.159   35.768  1.00 91.73  ? 555  THR D O   1 
ATOM   12044 C CB  . THR D 1 480 ? -76.490 3.296   38.859  1.00 86.56  ? 555  THR D CB  1 
ATOM   12045 O OG1 . THR D 1 480 ? -76.716 2.981   40.237  1.00 109.99 ? 555  THR D OG1 1 
ATOM   12046 C CG2 . THR D 1 480 ? -76.977 4.710   38.578  1.00 94.68  ? 555  THR D CG2 1 
ATOM   12047 N N   . GLN D 1 481 ? -75.700 2.017   36.091  1.00 97.18  ? 556  GLN D N   1 
ATOM   12048 C CA  . GLN D 1 481 ? -75.278 2.125   34.702  1.00 86.77  ? 556  GLN D CA  1 
ATOM   12049 C C   . GLN D 1 481 ? -76.255 1.414   33.780  1.00 91.91  ? 556  GLN D C   1 
ATOM   12050 O O   . GLN D 1 481 ? -76.627 1.949   32.732  1.00 105.33 ? 556  GLN D O   1 
ATOM   12051 C CB  . GLN D 1 481 ? -73.871 1.549   34.548  1.00 80.95  ? 556  GLN D CB  1 
ATOM   12052 C CG  . GLN D 1 481 ? -73.326 1.565   33.132  1.00 91.68  ? 556  GLN D CG  1 
ATOM   12053 C CD  . GLN D 1 481 ? -71.920 0.998   33.050  1.00 88.51  ? 556  GLN D CD  1 
ATOM   12054 O OE1 . GLN D 1 481 ? -71.701 -0.185  33.309  1.00 74.71  ? 556  GLN D OE1 1 
ATOM   12055 N NE2 . GLN D 1 481 ? -70.960 1.841   32.684  1.00 90.81  ? 556  GLN D NE2 1 
ATOM   12056 N N   . LEU D 1 482 ? -76.694 0.211   34.160  1.00 92.63  ? 557  LEU D N   1 
ATOM   12057 C CA  . LEU D 1 482 ? -77.674 -0.505  33.348  1.00 92.86  ? 557  LEU D CA  1 
ATOM   12058 C C   . LEU D 1 482 ? -78.980 0.274   33.250  1.00 92.79  ? 557  LEU D C   1 
ATOM   12059 O O   . LEU D 1 482 ? -79.553 0.414   32.162  1.00 87.68  ? 557  LEU D O   1 
ATOM   12060 C CB  . LEU D 1 482 ? -77.918 -1.901  33.923  1.00 79.87  ? 557  LEU D CB  1 
ATOM   12061 C CG  . LEU D 1 482 ? -76.745 -2.884  33.892  1.00 115.92 ? 557  LEU D CG  1 
ATOM   12062 C CD1 . LEU D 1 482 ? -77.239 -4.300  34.138  1.00 107.26 ? 557  LEU D CD1 1 
ATOM   12063 C CD2 . LEU D 1 482 ? -75.987 -2.797  32.572  1.00 130.26 ? 557  LEU D CD2 1 
ATOM   12064 N N   . ASP D 1 483 ? -79.463 0.798   34.381  1.00 91.88  ? 558  ASP D N   1 
ATOM   12065 C CA  . ASP D 1 483 ? -80.712 1.556   34.377  1.00 95.08  ? 558  ASP D CA  1 
ATOM   12066 C C   . ASP D 1 483 ? -80.619 2.771   33.463  1.00 95.44  ? 558  ASP D C   1 
ATOM   12067 O O   . ASP D 1 483 ? -81.462 2.962   32.575  1.00 101.59 ? 558  ASP D O   1 
ATOM   12068 C CB  . ASP D 1 483 ? -81.075 1.987   35.799  1.00 86.97  ? 558  ASP D CB  1 
ATOM   12069 C CG  . ASP D 1 483 ? -81.292 0.813   36.723  1.00 91.85  ? 558  ASP D CG  1 
ATOM   12070 O OD1 . ASP D 1 483 ? -81.250 -0.334  36.232  1.00 83.80  ? 558  ASP D OD1 1 
ATOM   12071 O OD2 . ASP D 1 483 ? -81.509 1.035   37.934  1.00 96.43  ? 558  ASP D OD2 1 
ATOM   12072 N N   . ASP D 1 484 ? -79.600 3.609   33.668  1.00 90.45  ? 559  ASP D N   1 
ATOM   12073 C CA  . ASP D 1 484 ? -79.507 4.832   32.879  1.00 91.11  ? 559  ASP D CA  1 
ATOM   12074 C C   . ASP D 1 484 ? -79.177 4.539   31.421  1.00 88.31  ? 559  ASP D C   1 
ATOM   12075 O O   . ASP D 1 484 ? -79.589 5.294   30.537  1.00 91.07  ? 559  ASP D O   1 
ATOM   12076 C CB  . ASP D 1 484 ? -78.492 5.800   33.498  1.00 83.97  ? 559  ASP D CB  1 
ATOM   12077 C CG  . ASP D 1 484 ? -77.069 5.266   33.487  1.00 119.15 ? 559  ASP D CG  1 
ATOM   12078 O OD1 . ASP D 1 484 ? -76.552 4.914   32.406  1.00 156.14 ? 559  ASP D OD1 1 
ATOM   12079 O OD2 . ASP D 1 484 ? -76.447 5.237   34.570  1.00 115.89 ? 559  ASP D OD2 1 
ATOM   12080 N N   . ARG D 1 485 ? -78.475 3.438   31.139  1.00 88.42  ? 560  ARG D N   1 
ATOM   12081 C CA  . ARG D 1 485 ? -78.202 3.075   29.754  1.00 91.61  ? 560  ARG D CA  1 
ATOM   12082 C C   . ARG D 1 485 ? -79.471 2.626   29.045  1.00 93.94  ? 560  ARG D C   1 
ATOM   12083 O O   . ARG D 1 485 ? -79.698 2.984   27.885  1.00 86.14  ? 560  ARG D O   1 
ATOM   12084 C CB  . ARG D 1 485 ? -77.138 1.978   29.695  1.00 87.89  ? 560  ARG D CB  1 
ATOM   12085 C CG  . ARG D 1 485 ? -76.836 1.492   28.286  1.00 103.88 ? 560  ARG D CG  1 
ATOM   12086 C CD  . ARG D 1 485 ? -75.616 0.585   28.242  1.00 101.38 ? 560  ARG D CD  1 
ATOM   12087 N NE  . ARG D 1 485 ? -74.380 1.296   28.546  1.00 107.74 ? 560  ARG D NE  1 
ATOM   12088 C CZ  . ARG D 1 485 ? -73.426 1.547   27.659  1.00 103.47 ? 560  ARG D CZ  1 
ATOM   12089 N NH1 . ARG D 1 485 ? -73.539 1.168   26.397  1.00 90.52  ? 560  ARG D NH1 1 
ATOM   12090 N NH2 . ARG D 1 485 ? -72.331 2.191   28.050  1.00 101.34 ? 560  ARG D NH2 1 
ATOM   12091 N N   . THR D 1 486 ? -80.313 1.841   29.725  1.00 96.55  ? 561  THR D N   1 
ATOM   12092 C CA  . THR D 1 486 ? -81.589 1.457   29.130  1.00 94.40  ? 561  THR D CA  1 
ATOM   12093 C C   . THR D 1 486 ? -82.486 2.672   28.926  1.00 93.23  ? 561  THR D C   1 
ATOM   12094 O O   . THR D 1 486 ? -83.167 2.782   27.899  1.00 99.78  ? 561  THR D O   1 
ATOM   12095 C CB  . THR D 1 486 ? -82.292 0.411   29.995  1.00 78.01  ? 561  THR D CB  1 
ATOM   12096 O OG1 . THR D 1 486 ? -82.422 0.900   31.336  1.00 108.97 ? 561  THR D OG1 1 
ATOM   12097 C CG2 . THR D 1 486 ? -81.517 -0.899  29.998  1.00 73.36  ? 561  THR D CG2 1 
ATOM   12098 N N   . ARG D 1 487 ? -82.497 3.598   29.890  1.00 86.08  ? 562  ARG D N   1 
ATOM   12099 C CA  . ARG D 1 487 ? -83.278 4.821   29.721  1.00 91.35  ? 562  ARG D CA  1 
ATOM   12100 C C   . ARG D 1 487 ? -82.785 5.625   28.524  1.00 97.82  ? 562  ARG D C   1 
ATOM   12101 O O   . ARG D 1 487 ? -83.584 6.082   27.697  1.00 109.29 ? 562  ARG D O   1 
ATOM   12102 C CB  . ARG D 1 487 ? -83.224 5.674   30.989  1.00 92.81  ? 562  ARG D CB  1 
ATOM   12103 C CG  . ARG D 1 487 ? -83.927 5.089   32.200  1.00 99.07  ? 562  ARG D CG  1 
ATOM   12104 C CD  . ARG D 1 487 ? -83.351 5.695   33.467  1.00 101.23 ? 562  ARG D CD  1 
ATOM   12105 N NE  . ARG D 1 487 ? -83.418 7.152   33.423  1.00 102.92 ? 562  ARG D NE  1 
ATOM   12106 C CZ  . ARG D 1 487 ? -82.768 7.961   34.249  1.00 113.04 ? 562  ARG D CZ  1 
ATOM   12107 N NH1 . ARG D 1 487 ? -81.982 7.490   35.203  1.00 122.07 ? 562  ARG D NH1 1 
ATOM   12108 N NH2 . ARG D 1 487 ? -82.907 9.276   34.110  1.00 104.90 ? 562  ARG D NH2 1 
ATOM   12109 N N   . ILE D 1 488 ? -81.467 5.822   28.426  1.00 90.76  ? 563  ILE D N   1 
ATOM   12110 C CA  . ILE D 1 488 ? -80.891 6.549   27.297  1.00 92.47  ? 563  ILE D CA  1 
ATOM   12111 C C   . ILE D 1 488 ? -81.269 5.876   25.988  1.00 95.28  ? 563  ILE D C   1 
ATOM   12112 O O   . ILE D 1 488 ? -81.720 6.530   25.041  1.00 102.64 ? 563  ILE D O   1 
ATOM   12113 C CB  . ILE D 1 488 ? -79.363 6.656   27.451  1.00 87.55  ? 563  ILE D CB  1 
ATOM   12114 C CG1 . ILE D 1 488 ? -79.000 7.628   28.572  1.00 91.18  ? 563  ILE D CG1 1 
ATOM   12115 C CG2 . ILE D 1 488 ? -78.717 7.090   26.144  1.00 83.95  ? 563  ILE D CG2 1 
ATOM   12116 C CD1 . ILE D 1 488 ? -77.580 7.471   29.059  1.00 92.39  ? 563  ILE D CD1 1 
ATOM   12117 N N   . THR D 1 489 ? -81.098 4.554   25.919  1.00 93.00  ? 564  THR D N   1 
ATOM   12118 C CA  . THR D 1 489 ? -81.399 3.829   24.692  1.00 98.99  ? 564  THR D CA  1 
ATOM   12119 C C   . THR D 1 489 ? -82.856 4.015   24.291  1.00 99.48  ? 564  THR D C   1 
ATOM   12120 O O   . THR D 1 489 ? -83.150 4.415   23.161  1.00 91.14  ? 564  THR D O   1 
ATOM   12121 C CB  . THR D 1 489 ? -81.074 2.346   24.861  1.00 95.27  ? 564  THR D CB  1 
ATOM   12122 O OG1 . THR D 1 489 ? -79.747 2.200   25.385  1.00 102.65 ? 564  THR D OG1 1 
ATOM   12123 C CG2 . THR D 1 489 ? -81.155 1.639   23.522  1.00 76.59  ? 564  THR D CG2 1 
ATOM   12124 N N   . GLU D 1 490 ? -83.784 3.764   25.217  1.00 100.69 ? 565  GLU D N   1 
ATOM   12125 C CA  . GLU D 1 490 ? -85.201 3.833   24.869  1.00 102.06 ? 565  GLU D CA  1 
ATOM   12126 C C   . GLU D 1 490 ? -85.630 5.253   24.513  1.00 104.89 ? 565  GLU D C   1 
ATOM   12127 O O   . GLU D 1 490 ? -86.344 5.456   23.525  1.00 117.61 ? 565  GLU D O   1 
ATOM   12128 C CB  . GLU D 1 490 ? -86.054 3.282   26.009  1.00 91.34  ? 565  GLU D CB  1 
ATOM   12129 C CG  . GLU D 1 490 ? -85.804 1.815   26.300  1.00 108.51 ? 565  GLU D CG  1 
ATOM   12130 C CD  . GLU D 1 490 ? -86.530 1.333   27.534  1.00 108.34 ? 565  GLU D CD  1 
ATOM   12131 O OE1 . GLU D 1 490 ? -87.771 1.210   27.480  1.00 116.44 ? 565  GLU D OE1 1 
ATOM   12132 O OE2 . GLU D 1 490 ? -85.858 1.076   28.555  1.00 113.02 ? 565  GLU D OE2 1 
ATOM   12133 N N   . LEU D 1 491 ? -85.206 6.248   25.295  1.00 98.19  ? 566  LEU D N   1 
ATOM   12134 C CA  . LEU D 1 491 ? -85.614 7.623   25.025  1.00 101.18 ? 566  LEU D CA  1 
ATOM   12135 C C   . LEU D 1 491 ? -85.025 8.128   23.714  1.00 108.23 ? 566  LEU D C   1 
ATOM   12136 O O   . LEU D 1 491 ? -85.740 8.660   22.854  1.00 115.17 ? 566  LEU D O   1 
ATOM   12137 C CB  . LEU D 1 491 ? -85.194 8.527   26.185  1.00 96.08  ? 566  LEU D CB  1 
ATOM   12138 C CG  . LEU D 1 491 ? -85.424 10.033  26.042  1.00 102.39 ? 566  LEU D CG  1 
ATOM   12139 C CD1 . LEU D 1 491 ? -86.893 10.371  26.227  1.00 106.43 ? 566  LEU D CD1 1 
ATOM   12140 C CD2 . LEU D 1 491 ? -84.566 10.802  27.036  1.00 114.52 ? 566  LEU D CD2 1 
ATOM   12141 N N   . PHE D 1 492 ? -83.716 7.975   23.535  1.00 106.23 ? 567  PHE D N   1 
ATOM   12142 C CA  . PHE D 1 492 ? -83.078 8.567   22.375  1.00 110.52 ? 567  PHE D CA  1 
ATOM   12143 C C   . PHE D 1 492 ? -83.198 7.724   21.115  1.00 103.30 ? 567  PHE D C   1 
ATOM   12144 O O   . PHE D 1 492 ? -82.981 8.269   20.035  1.00 97.07  ? 567  PHE D O   1 
ATOM   12145 C CB  . PHE D 1 492 ? -81.615 8.876   22.696  1.00 100.48 ? 567  PHE D CB  1 
ATOM   12146 C CG  . PHE D 1 492 ? -81.451 9.991   23.683  1.00 94.96  ? 567  PHE D CG  1 
ATOM   12147 C CD1 . PHE D 1 492 ? -81.728 11.297  23.312  1.00 86.54  ? 567  PHE D CD1 1 
ATOM   12148 C CD2 . PHE D 1 492 ? -81.068 9.737   24.989  1.00 95.58  ? 567  PHE D CD2 1 
ATOM   12149 C CE1 . PHE D 1 492 ? -81.596 12.332  24.212  1.00 86.76  ? 567  PHE D CE1 1 
ATOM   12150 C CE2 . PHE D 1 492 ? -80.940 10.769  25.899  1.00 102.21 ? 567  PHE D CE2 1 
ATOM   12151 C CZ  . PHE D 1 492 ? -81.202 12.069  25.508  1.00 97.73  ? 567  PHE D CZ  1 
ATOM   12152 N N   . ALA D 1 493 ? -83.603 6.453   21.203  1.00 95.21  ? 568  ALA D N   1 
ATOM   12153 C CA  . ALA D 1 493 ? -83.947 5.721   19.990  1.00 98.21  ? 568  ALA D CA  1 
ATOM   12154 C C   . ALA D 1 493 ? -85.029 6.453   19.211  1.00 102.91 ? 568  ALA D C   1 
ATOM   12155 O O   . ALA D 1 493 ? -85.023 6.456   17.974  1.00 94.33  ? 568  ALA D O   1 
ATOM   12156 C CB  . ALA D 1 493 ? -84.395 4.303   20.342  1.00 88.89  ? 568  ALA D CB  1 
ATOM   12157 N N   . VAL D 1 494 ? -85.949 7.102   19.920  1.00 104.08 ? 569  VAL D N   1 
ATOM   12158 C CA  . VAL D 1 494 ? -86.979 7.910   19.281  1.00 97.99  ? 569  VAL D CA  1 
ATOM   12159 C C   . VAL D 1 494 ? -86.548 9.367   19.161  1.00 100.32 ? 569  VAL D C   1 
ATOM   12160 O O   . VAL D 1 494 ? -86.831 10.020  18.154  1.00 110.27 ? 569  VAL D O   1 
ATOM   12161 C CB  . VAL D 1 494 ? -88.302 7.774   20.060  1.00 85.12  ? 569  VAL D CB  1 
ATOM   12162 C CG1 . VAL D 1 494 ? -89.448 8.424   19.292  1.00 108.99 ? 569  VAL D CG1 1 
ATOM   12163 C CG2 . VAL D 1 494 ? -88.599 6.310   20.350  1.00 88.27  ? 569  VAL D CG2 1 
ATOM   12164 N N   . ALA D 1 495 ? -85.844 9.896   20.167  1.00 95.22  ? 570  ALA D N   1 
ATOM   12165 C CA  . ALA D 1 495 ? -85.512 11.320  20.160  1.00 106.01 ? 570  ALA D CA  1 
ATOM   12166 C C   . ALA D 1 495 ? -84.469 11.665  19.098  1.00 106.75 ? 570  ALA D C   1 
ATOM   12167 O O   . ALA D 1 495 ? -84.562 12.716  18.453  1.00 98.32  ? 570  ALA D O   1 
ATOM   12168 C CB  . ALA D 1 495 ? -85.029 11.749  21.545  1.00 102.24 ? 570  ALA D CB  1 
ATOM   12169 N N   . LEU D 1 496 ? -83.474 10.799  18.897  1.00 101.67 ? 571  LEU D N   1 
ATOM   12170 C CA  . LEU D 1 496 ? -82.349 11.134  18.031  1.00 98.00  ? 571  LEU D CA  1 
ATOM   12171 C C   . LEU D 1 496 ? -82.732 11.314  16.567  1.00 108.93 ? 571  LEU D C   1 
ATOM   12172 O O   . LEU D 1 496 ? -82.179 12.225  15.929  1.00 111.31 ? 571  LEU D O   1 
ATOM   12173 C CB  . LEU D 1 496 ? -81.255 10.070  18.179  1.00 88.72  ? 571  LEU D CB  1 
ATOM   12174 C CG  . LEU D 1 496 ? -79.946 10.344  17.439  1.00 86.71  ? 571  LEU D CG  1 
ATOM   12175 C CD1 . LEU D 1 496 ? -79.413 11.726  17.779  1.00 86.96  ? 571  LEU D CD1 1 
ATOM   12176 C CD2 . LEU D 1 496 ? -78.927 9.275   17.766  1.00 80.34  ? 571  LEU D CD2 1 
ATOM   12177 N N   . PRO D 1 497 ? -83.605 10.498  15.964  1.00 99.10  ? 572  PRO D N   1 
ATOM   12178 C CA  . PRO D 1 497 ? -84.059 10.837  14.602  1.00 97.56  ? 572  PRO D CA  1 
ATOM   12179 C C   . PRO D 1 497 ? -84.687 12.217  14.528  1.00 98.40  ? 572  PRO D C   1 
ATOM   12180 O O   . PRO D 1 497 ? -84.357 13.009  13.633  1.00 91.37  ? 572  PRO D O   1 
ATOM   12181 C CB  . PRO D 1 497 ? -85.061 9.720   14.291  1.00 97.23  ? 572  PRO D CB  1 
ATOM   12182 C CG  . PRO D 1 497 ? -84.552 8.558   15.059  1.00 94.27  ? 572  PRO D CG  1 
ATOM   12183 C CD  . PRO D 1 497 ? -84.016 9.133   16.345  1.00 85.58  ? 572  PRO D CD  1 
ATOM   12184 N N   . GLN D 1 498 ? -85.575 12.531  15.473  1.00 99.98  ? 573  GLN D N   1 
ATOM   12185 C CA  . GLN D 1 498 ? -86.199 13.848  15.513  1.00 103.03 ? 573  GLN D CA  1 
ATOM   12186 C C   . GLN D 1 498 ? -85.154 14.943  15.691  1.00 102.94 ? 573  GLN D C   1 
ATOM   12187 O O   . GLN D 1 498 ? -85.141 15.932  14.949  1.00 107.83 ? 573  GLN D O   1 
ATOM   12188 C CB  . GLN D 1 498 ? -87.221 13.898  16.648  1.00 103.49 ? 573  GLN D CB  1 
ATOM   12189 C CG  . GLN D 1 498 ? -88.181 12.724  16.664  1.00 107.51 ? 573  GLN D CG  1 
ATOM   12190 C CD  . GLN D 1 498 ? -89.126 12.769  17.846  1.00 115.28 ? 573  GLN D CD  1 
ATOM   12191 O OE1 . GLN D 1 498 ? -89.079 11.909  18.726  1.00 118.78 ? 573  GLN D OE1 1 
ATOM   12192 N NE2 . GLN D 1 498 ? -89.992 13.775  17.874  1.00 125.15 ? 573  GLN D NE2 1 
ATOM   12193 N N   . LEU D 1 499 ? -84.268 14.777  16.681  1.00 99.82  ? 574  LEU D N   1 
ATOM   12194 C CA  . LEU D 1 499 ? -83.240 15.777  16.955  1.00 99.21  ? 574  LEU D CA  1 
ATOM   12195 C C   . LEU D 1 499 ? -82.362 16.016  15.736  1.00 103.20 ? 574  LEU D C   1 
ATOM   12196 O O   . LEU D 1 499 ? -82.036 17.163  15.406  1.00 96.57  ? 574  LEU D O   1 
ATOM   12197 C CB  . LEU D 1 499 ? -82.387 15.329  18.142  1.00 103.94 ? 574  LEU D CB  1 
ATOM   12198 C CG  . LEU D 1 499 ? -82.967 15.477  19.547  1.00 98.35  ? 574  LEU D CG  1 
ATOM   12199 C CD1 . LEU D 1 499 ? -82.177 14.631  20.532  1.00 107.96 ? 574  LEU D CD1 1 
ATOM   12200 C CD2 . LEU D 1 499 ? -82.955 16.935  19.970  1.00 97.87  ? 574  LEU D CD2 1 
ATOM   12201 N N   . LEU D 1 500 ? -81.964 14.938  15.058  1.00 104.21 ? 575  LEU D N   1 
ATOM   12202 C CA  . LEU D 1 500 ? -81.142 15.060  13.862  1.00 104.66 ? 575  LEU D CA  1 
ATOM   12203 C C   . LEU D 1 500 ? -81.898 15.775  12.750  1.00 100.72 ? 575  LEU D C   1 
ATOM   12204 O O   . LEU D 1 500 ? -81.318 16.579  12.011  1.00 97.50  ? 575  LEU D O   1 
ATOM   12205 C CB  . LEU D 1 500 ? -80.699 13.670  13.405  1.00 100.38 ? 575  LEU D CB  1 
ATOM   12206 C CG  . LEU D 1 500 ? -79.480 13.019  14.060  1.00 94.71  ? 575  LEU D CG  1 
ATOM   12207 C CD1 . LEU D 1 500 ? -79.231 11.647  13.452  1.00 80.06  ? 575  LEU D CD1 1 
ATOM   12208 C CD2 . LEU D 1 500 ? -78.251 13.899  13.917  1.00 99.68  ? 575  LEU D CD2 1 
ATOM   12209 N N   . ALA D 1 501 ? -83.198 15.495  12.618  1.00 98.22  ? 576  ALA D N   1 
ATOM   12210 C CA  . ALA D 1 501 ? -83.990 16.142  11.577  1.00 86.25  ? 576  ALA D CA  1 
ATOM   12211 C C   . ALA D 1 501 ? -84.119 17.640  11.825  1.00 97.63  ? 576  ALA D C   1 
ATOM   12212 O O   . ALA D 1 501 ? -84.017 18.442  10.888  1.00 101.87 ? 576  ALA D O   1 
ATOM   12213 C CB  . ALA D 1 501 ? -85.370 15.491  11.492  1.00 89.76  ? 576  ALA D CB  1 
ATOM   12214 N N   . LYS D 1 502 ? -84.347 18.038  13.081  1.00 103.22 ? 577  LYS D N   1 
ATOM   12215 C CA  . LYS D 1 502 ? -84.503 19.458  13.386  1.00 98.03  ? 577  LYS D CA  1 
ATOM   12216 C C   . LYS D 1 502 ? -83.219 20.231  13.109  1.00 105.25 ? 577  LYS D C   1 
ATOM   12217 O O   . LYS D 1 502 ? -83.263 21.388  12.673  1.00 110.74 ? 577  LYS D O   1 
ATOM   12218 C CB  . LYS D 1 502 ? -84.924 19.656  14.844  1.00 99.94  ? 577  LYS D CB  1 
ATOM   12219 C CG  . LYS D 1 502 ? -86.106 18.820  15.314  1.00 123.06 ? 577  LYS D CG  1 
ATOM   12220 C CD  . LYS D 1 502 ? -87.266 18.847  14.333  1.00 135.73 ? 577  LYS D CD  1 
ATOM   12221 C CE  . LYS D 1 502 ? -88.253 17.728  14.626  1.00 131.22 ? 577  LYS D CE  1 
ATOM   12222 N NZ  . LYS D 1 502 ? -88.671 17.723  16.057  1.00 141.41 ? 577  LYS D NZ  1 
ATOM   12223 N N   . TYR D 1 503 ? -82.065 19.608  13.352  1.00 97.81  ? 578  TYR D N   1 
ATOM   12224 C CA  . TYR D 1 503 ? -80.775 20.285  13.296  1.00 100.09 ? 578  TYR D CA  1 
ATOM   12225 C C   . TYR D 1 503 ? -79.874 19.697  12.214  1.00 106.37 ? 578  TYR D C   1 
ATOM   12226 O O   . TYR D 1 503 ? -78.651 19.679  12.363  1.00 110.84 ? 578  TYR D O   1 
ATOM   12227 C CB  . TYR D 1 503 ? -80.080 20.216  14.654  1.00 111.85 ? 578  TYR D CB  1 
ATOM   12228 C CG  . TYR D 1 503 ? -80.923 20.711  15.806  1.00 104.70 ? 578  TYR D CG  1 
ATOM   12229 C CD1 . TYR D 1 503 ? -81.394 22.017  15.838  1.00 100.72 ? 578  TYR D CD1 1 
ATOM   12230 C CD2 . TYR D 1 503 ? -81.250 19.870  16.862  1.00 100.37 ? 578  TYR D CD2 1 
ATOM   12231 C CE1 . TYR D 1 503 ? -82.166 22.472  16.889  1.00 105.97 ? 578  TYR D CE1 1 
ATOM   12232 C CE2 . TYR D 1 503 ? -82.022 20.316  17.917  1.00 107.41 ? 578  TYR D CE2 1 
ATOM   12233 C CZ  . TYR D 1 503 ? -82.477 21.617  17.926  1.00 114.94 ? 578  TYR D CZ  1 
ATOM   12234 O OH  . TYR D 1 503 ? -83.246 22.068  18.975  1.00 127.36 ? 578  TYR D OH  1 
ATOM   12235 N N   . SER D 1 504 ? -80.467 19.218  11.116  1.00 110.26 ? 579  SER D N   1 
ATOM   12236 C CA  . SER D 1 504 ? -79.683 18.560  10.074  1.00 102.39 ? 579  SER D CA  1 
ATOM   12237 C C   . SER D 1 504 ? -78.644 19.498  9.475   1.00 101.25 ? 579  SER D C   1 
ATOM   12238 O O   . SER D 1 504 ? -77.548 19.065  9.100   1.00 105.50 ? 579  SER D O   1 
ATOM   12239 C CB  . SER D 1 504 ? -80.609 18.027  8.981   1.00 105.79 ? 579  SER D CB  1 
ATOM   12240 O OG  . SER D 1 504 ? -81.434 16.984  9.469   1.00 112.63 ? 579  SER D OG  1 
ATOM   12241 N N   . VAL D 1 505 ? -78.967 20.788  9.381   1.00 108.86 ? 580  VAL D N   1 
ATOM   12242 C CA  . VAL D 1 505 ? -78.061 21.732  8.732   1.00 110.04 ? 580  VAL D CA  1 
ATOM   12243 C C   . VAL D 1 505 ? -76.854 22.019  9.619   1.00 114.00 ? 580  VAL D C   1 
ATOM   12244 O O   . VAL D 1 505 ? -75.730 22.181  9.127   1.00 116.28 ? 580  VAL D O   1 
ATOM   12245 C CB  . VAL D 1 505 ? -78.821 23.019  8.360   1.00 115.79 ? 580  VAL D CB  1 
ATOM   12246 C CG1 . VAL D 1 505 ? -79.506 23.611  9.585   1.00 122.02 ? 580  VAL D CG1 1 
ATOM   12247 C CG2 . VAL D 1 505 ? -77.883 24.035  7.724   1.00 113.01 ? 580  VAL D CG2 1 
ATOM   12248 N N   . ASP D 1 506 ? -77.059 22.074  10.932  1.00 114.91 ? 581  ASP D N   1 
ATOM   12249 C CA  . ASP D 1 506 ? -75.986 22.443  11.848  1.00 112.17 ? 581  ASP D CA  1 
ATOM   12250 C C   . ASP D 1 506 ? -75.000 21.288  11.987  1.00 110.92 ? 581  ASP D C   1 
ATOM   12251 O O   . ASP D 1 506 ? -75.388 20.173  12.352  1.00 108.19 ? 581  ASP D O   1 
ATOM   12252 C CB  . ASP D 1 506 ? -76.570 22.827  13.206  1.00 108.41 ? 581  ASP D CB  1 
ATOM   12253 C CG  . ASP D 1 506 ? -75.551 23.479  14.117  1.00 120.72 ? 581  ASP D CG  1 
ATOM   12254 O OD1 . ASP D 1 506 ? -74.524 22.840  14.429  1.00 132.73 ? 581  ASP D OD1 1 
ATOM   12255 O OD2 . ASP D 1 506 ? -75.780 24.637  14.521  1.00 116.05 ? 581  ASP D OD2 1 
ATOM   12256 N N   . ALA D 1 507 ? -73.721 21.562  11.715  1.00 108.11 ? 582  ALA D N   1 
ATOM   12257 C CA  . ALA D 1 507 ? -72.714 20.506  11.692  1.00 105.03 ? 582  ALA D CA  1 
ATOM   12258 C C   . ALA D 1 507 ? -72.301 20.085  13.099  1.00 101.38 ? 582  ALA D C   1 
ATOM   12259 O O   . ALA D 1 507 ? -72.186 18.888  13.387  1.00 102.80 ? 582  ALA D O   1 
ATOM   12260 C CB  . ALA D 1 507 ? -71.493 20.961  10.891  1.00 90.88  ? 582  ALA D CB  1 
ATOM   12261 N N   . GLU D 1 508 ? -72.054 21.056  13.982  1.00 96.52  ? 583  GLU D N   1 
ATOM   12262 C CA  . GLU D 1 508 ? -71.701 20.734  15.361  1.00 93.05  ? 583  GLU D CA  1 
ATOM   12263 C C   . GLU D 1 508 ? -72.777 19.872  16.007  1.00 96.90  ? 583  GLU D C   1 
ATOM   12264 O O   . GLU D 1 508 ? -72.482 18.862  16.663  1.00 108.36 ? 583  GLU D O   1 
ATOM   12265 C CB  . GLU D 1 508 ? -71.509 22.019  16.165  1.00 86.39  ? 583  GLU D CB  1 
ATOM   12266 C CG  . GLU D 1 508 ? -70.450 22.967  15.633  1.00 99.94  ? 583  GLU D CG  1 
ATOM   12267 C CD  . GLU D 1 508 ? -70.618 24.366  16.191  1.00 114.60 ? 583  GLU D CD  1 
ATOM   12268 O OE1 . GLU D 1 508 ? -71.640 24.609  16.870  1.00 124.59 ? 583  GLU D OE1 1 
ATOM   12269 O OE2 . GLU D 1 508 ? -69.739 25.222  15.953  1.00 104.65 ? 583  GLU D OE2 1 
ATOM   12270 N N   . LYS D 1 509 ? -74.040 20.265  15.826  1.00 87.92  ? 584  LYS D N   1 
ATOM   12271 C CA  . LYS D 1 509 ? -75.142 19.550  16.456  1.00 91.58  ? 584  LYS D CA  1 
ATOM   12272 C C   . LYS D 1 509 ? -75.229 18.115  15.956  1.00 92.25  ? 584  LYS D C   1 
ATOM   12273 O O   . LYS D 1 509 ? -75.411 17.190  16.753  1.00 95.00  ? 584  LYS D O   1 
ATOM   12274 C CB  . LYS D 1 509 ? -76.455 20.292  16.211  1.00 108.68 ? 584  LYS D CB  1 
ATOM   12275 C CG  . LYS D 1 509 ? -76.593 21.578  17.011  1.00 123.70 ? 584  LYS D CG  1 
ATOM   12276 C CD  . LYS D 1 509 ? -77.948 22.227  16.786  1.00 120.00 ? 584  LYS D CD  1 
ATOM   12277 C CE  . LYS D 1 509 ? -78.068 23.545  17.532  1.00 124.13 ? 584  LYS D CE  1 
ATOM   12278 N NZ  . LYS D 1 509 ? -77.104 24.565  17.032  1.00 129.46 ? 584  LYS D NZ  1 
ATOM   12279 N N   . VAL D 1 510 ? -75.088 17.901  14.645  1.00 87.07  ? 585  VAL D N   1 
ATOM   12280 C CA  . VAL D 1 510 ? -75.210 16.542  14.128  1.00 102.16 ? 585  VAL D CA  1 
ATOM   12281 C C   . VAL D 1 510 ? -74.011 15.699  14.544  1.00 96.74  ? 585  VAL D C   1 
ATOM   12282 O O   . VAL D 1 510 ? -74.156 14.508  14.837  1.00 88.25  ? 585  VAL D O   1 
ATOM   12283 C CB  . VAL D 1 510 ? -75.404 16.532  12.598  1.00 102.74 ? 585  VAL D CB  1 
ATOM   12284 C CG1 . VAL D 1 510 ? -76.751 17.125  12.223  1.00 101.03 ? 585  VAL D CG1 1 
ATOM   12285 C CG2 . VAL D 1 510 ? -74.268 17.238  11.886  1.00 92.31  ? 585  VAL D CG2 1 
ATOM   12286 N N   . THR D 1 511 ? -72.814 16.294  14.596  1.00 94.62  ? 586  THR D N   1 
ATOM   12287 C CA  . THR D 1 511 ? -71.658 15.541  15.078  1.00 87.64  ? 586  THR D CA  1 
ATOM   12288 C C   . THR D 1 511 ? -71.866 15.083  16.515  1.00 94.13  ? 586  THR D C   1 
ATOM   12289 O O   . THR D 1 511 ? -71.626 13.916  16.845  1.00 90.90  ? 586  THR D O   1 
ATOM   12290 C CB  . THR D 1 511 ? -70.372 16.365  14.966  1.00 80.61  ? 586  THR D CB  1 
ATOM   12291 O OG1 . THR D 1 511 ? -70.506 17.591  15.698  1.00 103.31 ? 586  THR D OG1 1 
ATOM   12292 C CG2 . THR D 1 511 ? -70.028 16.647  13.522  1.00 67.43  ? 586  THR D CG2 1 
ATOM   12293 N N   . ASN D 1 512 ? -72.311 15.990  17.389  1.00 90.74  ? 587  ASN D N   1 
ATOM   12294 C CA  . ASN D 1 512 ? -72.538 15.605  18.778  1.00 77.08  ? 587  ASN D CA  1 
ATOM   12295 C C   . ASN D 1 512 ? -73.657 14.576  18.894  1.00 84.55  ? 587  ASN D C   1 
ATOM   12296 O O   . ASN D 1 512 ? -73.539 13.602  19.647  1.00 88.92  ? 587  ASN D O   1 
ATOM   12297 C CB  . ASN D 1 512 ? -72.846 16.839  19.626  1.00 70.48  ? 587  ASN D CB  1 
ATOM   12298 C CG  . ASN D 1 512 ? -71.627 17.716  19.847  1.00 95.36  ? 587  ASN D CG  1 
ATOM   12299 O OD1 . ASN D 1 512 ? -71.725 18.783  20.452  1.00 98.72  ? 587  ASN D OD1 1 
ATOM   12300 N ND2 . ASN D 1 512 ? -70.468 17.257  19.384  1.00 99.65  ? 587  ASN D ND2 1 
ATOM   12301 N N   . LEU D 1 513 ? -74.743 14.763  18.138  1.00 83.96  ? 588  LEU D N   1 
ATOM   12302 C CA  . LEU D 1 513 ? -75.894 13.874  18.242  1.00 96.24  ? 588  LEU D CA  1 
ATOM   12303 C C   . LEU D 1 513 ? -75.578 12.476  17.726  1.00 99.02  ? 588  LEU D C   1 
ATOM   12304 O O   . LEU D 1 513 ? -76.097 11.489  18.259  1.00 101.31 ? 588  LEU D O   1 
ATOM   12305 C CB  . LEU D 1 513 ? -77.076 14.470  17.476  1.00 89.37  ? 588  LEU D CB  1 
ATOM   12306 C CG  . LEU D 1 513 ? -77.770 15.690  18.086  1.00 96.76  ? 588  LEU D CG  1 
ATOM   12307 C CD1 . LEU D 1 513 ? -78.879 16.175  17.166  1.00 99.85  ? 588  LEU D CD1 1 
ATOM   12308 C CD2 . LEU D 1 513 ? -78.318 15.365  19.466  1.00 93.93  ? 588  LEU D CD2 1 
ATOM   12309 N N   . LEU D 1 514 ? -74.732 12.372  16.698  1.00 97.12  ? 589  LEU D N   1 
ATOM   12310 C CA  . LEU D 1 514 ? -74.381 11.086  16.112  1.00 86.84  ? 589  LEU D CA  1 
ATOM   12311 C C   . LEU D 1 514 ? -73.560 10.210  17.048  1.00 98.64  ? 589  LEU D C   1 
ATOM   12312 O O   . LEU D 1 514 ? -73.424 9.012   16.781  1.00 103.80 ? 589  LEU D O   1 
ATOM   12313 C CB  . LEU D 1 514 ? -73.611 11.319  14.814  1.00 81.56  ? 589  LEU D CB  1 
ATOM   12314 C CG  . LEU D 1 514 ? -74.469 11.657  13.597  1.00 82.41  ? 589  LEU D CG  1 
ATOM   12315 C CD1 . LEU D 1 514 ? -73.572 11.955  12.419  1.00 77.95  ? 589  LEU D CD1 1 
ATOM   12316 C CD2 . LEU D 1 514 ? -75.449 10.539  13.275  1.00 83.18  ? 589  LEU D CD2 1 
ATOM   12317 N N   . GLN D 1 515 ? -73.006 10.777  18.121  1.00 102.39 ? 590  GLN D N   1 
ATOM   12318 C CA  . GLN D 1 515 ? -72.256 10.008  19.104  1.00 98.83  ? 590  GLN D CA  1 
ATOM   12319 C C   . GLN D 1 515 ? -73.157 9.278   20.088  1.00 89.77  ? 590  GLN D C   1 
ATOM   12320 O O   . GLN D 1 515 ? -72.670 8.413   20.825  1.00 95.83  ? 590  GLN D O   1 
ATOM   12321 C CB  . GLN D 1 515 ? -71.302 10.930  19.869  1.00 90.93  ? 590  GLN D CB  1 
ATOM   12322 C CG  . GLN D 1 515 ? -70.193 11.518  19.014  1.00 97.42  ? 590  GLN D CG  1 
ATOM   12323 C CD  . GLN D 1 515 ? -69.444 12.635  19.716  1.00 112.66 ? 590  GLN D CD  1 
ATOM   12324 O OE1 . GLN D 1 515 ? -68.862 12.438  20.784  1.00 114.19 ? 590  GLN D OE1 1 
ATOM   12325 N NE2 . GLN D 1 515 ? -69.461 13.820  19.118  1.00 114.73 ? 590  GLN D NE2 1 
ATOM   12326 N N   . LEU D 1 516 ? -74.448 9.606   20.112  1.00 80.13  ? 591  LEU D N   1 
ATOM   12327 C CA  . LEU D 1 516 ? -75.364 8.976   21.061  1.00 87.04  ? 591  LEU D CA  1 
ATOM   12328 C C   . LEU D 1 516 ? -75.496 7.470   20.865  1.00 86.65  ? 591  LEU D C   1 
ATOM   12329 O O   . LEU D 1 516 ? -75.462 6.740   21.870  1.00 85.27  ? 591  LEU D O   1 
ATOM   12330 C CB  . LEU D 1 516 ? -76.732 9.664   20.989  1.00 76.43  ? 591  LEU D CB  1 
ATOM   12331 C CG  . LEU D 1 516 ? -76.790 11.121  21.449  1.00 82.79  ? 591  LEU D CG  1 
ATOM   12332 C CD1 . LEU D 1 516 ? -78.231 11.561  21.689  1.00 83.42  ? 591  LEU D CD1 1 
ATOM   12333 C CD2 . LEU D 1 516 ? -75.936 11.333  22.688  1.00 80.18  ? 591  LEU D CD2 1 
ATOM   12334 N N   . PRO D 1 517 ? -75.658 6.936   19.644  1.00 83.95  ? 592  PRO D N   1 
ATOM   12335 C CA  . PRO D 1 517 ? -75.854 5.480   19.518  1.00 77.44  ? 592  PRO D CA  1 
ATOM   12336 C C   . PRO D 1 517 ? -74.711 4.652   20.077  1.00 86.79  ? 592  PRO D C   1 
ATOM   12337 O O   . PRO D 1 517 ? -74.930 3.490   20.444  1.00 90.20  ? 592  PRO D O   1 
ATOM   12338 C CB  . PRO D 1 517 ? -76.001 5.281   18.005  1.00 80.96  ? 592  PRO D CB  1 
ATOM   12339 C CG  . PRO D 1 517 ? -76.550 6.563   17.524  1.00 87.84  ? 592  PRO D CG  1 
ATOM   12340 C CD  . PRO D 1 517 ? -75.851 7.607   18.345  1.00 87.92  ? 592  PRO D CD  1 
ATOM   12341 N N   . GLN D 1 518 ? -73.500 5.213   20.160  1.00 80.57  ? 593  GLN D N   1 
ATOM   12342 C CA  . GLN D 1 518 ? -72.387 4.487   20.765  1.00 76.87  ? 593  GLN D CA  1 
ATOM   12343 C C   . GLN D 1 518 ? -72.710 4.049   22.186  1.00 87.78  ? 593  GLN D C   1 
ATOM   12344 O O   . GLN D 1 518 ? -72.198 3.026   22.653  1.00 94.78  ? 593  GLN D O   1 
ATOM   12345 C CB  . GLN D 1 518 ? -71.130 5.356   20.771  1.00 85.42  ? 593  GLN D CB  1 
ATOM   12346 C CG  . GLN D 1 518 ? -70.762 5.956   19.428  1.00 112.66 ? 593  GLN D CG  1 
ATOM   12347 C CD  . GLN D 1 518 ? -69.713 7.040   19.567  1.00 116.29 ? 593  GLN D CD  1 
ATOM   12348 O OE1 . GLN D 1 518 ? -69.270 7.347   20.675  1.00 85.36  ? 593  GLN D OE1 1 
ATOM   12349 N NE2 . GLN D 1 518 ? -69.312 7.627   18.446  1.00 124.62 ? 593  GLN D NE2 1 
ATOM   12350 N N   . TYR D 1 519 ? -73.557 4.805   22.883  1.00 91.82  ? 594  TYR D N   1 
ATOM   12351 C CA  . TYR D 1 519 ? -73.890 4.559   24.276  1.00 81.85  ? 594  TYR D CA  1 
ATOM   12352 C C   . TYR D 1 519 ? -75.213 3.823   24.443  1.00 88.62  ? 594  TYR D C   1 
ATOM   12353 O O   . TYR D 1 519 ? -75.750 3.779   25.554  1.00 87.81  ? 594  TYR D O   1 
ATOM   12354 C CB  . TYR D 1 519 ? -73.925 5.885   25.036  1.00 73.20  ? 594  TYR D CB  1 
ATOM   12355 C CG  . TYR D 1 519 ? -72.723 6.766   24.766  1.00 78.01  ? 594  TYR D CG  1 
ATOM   12356 C CD1 . TYR D 1 519 ? -71.441 6.354   25.107  1.00 87.10  ? 594  TYR D CD1 1 
ATOM   12357 C CD2 . TYR D 1 519 ? -72.871 8.010   24.166  1.00 77.00  ? 594  TYR D CD2 1 
ATOM   12358 C CE1 . TYR D 1 519 ? -70.342 7.155   24.861  1.00 86.00  ? 594  TYR D CE1 1 
ATOM   12359 C CE2 . TYR D 1 519 ? -71.778 8.818   23.916  1.00 82.68  ? 594  TYR D CE2 1 
ATOM   12360 C CZ  . TYR D 1 519 ? -70.515 8.386   24.266  1.00 85.99  ? 594  TYR D CZ  1 
ATOM   12361 O OH  . TYR D 1 519 ? -69.420 9.186   24.019  1.00 93.42  ? 594  TYR D OH  1 
ATOM   12362 N N   . PHE D 1 520 ? -75.745 3.247   23.370  1.00 90.01  ? 595  PHE D N   1 
ATOM   12363 C CA  . PHE D 1 520 ? -77.014 2.539   23.397  1.00 87.83  ? 595  PHE D CA  1 
ATOM   12364 C C   . PHE D 1 520 ? -76.781 1.047   23.597  1.00 89.89  ? 595  PHE D C   1 
ATOM   12365 O O   . PHE D 1 520 ? -75.702 0.518   23.315  1.00 95.68  ? 595  PHE D O   1 
ATOM   12366 C CB  . PHE D 1 520 ? -77.796 2.751   22.095  1.00 89.83  ? 595  PHE D CB  1 
ATOM   12367 C CG  . PHE D 1 520 ? -78.301 4.152   21.893  1.00 82.06  ? 595  PHE D CG  1 
ATOM   12368 C CD1 . PHE D 1 520 ? -78.086 5.139   22.841  1.00 94.72  ? 595  PHE D CD1 1 
ATOM   12369 C CD2 . PHE D 1 520 ? -78.996 4.482   20.741  1.00 72.37  ? 595  PHE D CD2 1 
ATOM   12370 C CE1 . PHE D 1 520 ? -78.551 6.424   22.641  1.00 99.65  ? 595  PHE D CE1 1 
ATOM   12371 C CE2 . PHE D 1 520 ? -79.462 5.763   20.536  1.00 83.48  ? 595  PHE D CE2 1 
ATOM   12372 C CZ  . PHE D 1 520 ? -79.239 6.735   21.486  1.00 89.42  ? 595  PHE D CZ  1 
ATOM   12373 N N   . ASP D 1 521 ? -77.816 0.369   24.087  1.00 79.21  ? 596  ASP D N   1 
ATOM   12374 C CA  . ASP D 1 521 ? -77.887 -1.089  24.047  1.00 101.01 ? 596  ASP D CA  1 
ATOM   12375 C C   . ASP D 1 521 ? -78.732 -1.436  22.826  1.00 100.80 ? 596  ASP D C   1 
ATOM   12376 O O   . ASP D 1 521 ? -79.959 -1.327  22.857  1.00 102.23 ? 596  ASP D O   1 
ATOM   12377 C CB  . ASP D 1 521 ? -78.479 -1.660  25.331  1.00 105.33 ? 596  ASP D CB  1 
ATOM   12378 C CG  . ASP D 1 521 ? -78.612 -3.176  25.289  1.00 129.11 ? 596  ASP D CG  1 
ATOM   12379 O OD1 . ASP D 1 521 ? -77.586 -3.857  25.078  1.00 136.16 ? 596  ASP D OD1 1 
ATOM   12380 O OD2 . ASP D 1 521 ? -79.739 -3.688  25.462  1.00 126.82 ? 596  ASP D OD2 1 
ATOM   12381 N N   . LEU D 1 522 ? -78.068 -1.851  21.745  1.00 95.22  ? 597  LEU D N   1 
ATOM   12382 C CA  . LEU D 1 522 ? -78.754 -2.069  20.476  1.00 96.60  ? 597  LEU D CA  1 
ATOM   12383 C C   . LEU D 1 522 ? -79.771 -3.204  20.543  1.00 100.57 ? 597  LEU D C   1 
ATOM   12384 O O   . LEU D 1 522 ? -80.652 -3.281  19.680  1.00 106.16 ? 597  LEU D O   1 
ATOM   12385 C CB  . LEU D 1 522 ? -77.725 -2.346  19.378  1.00 100.01 ? 597  LEU D CB  1 
ATOM   12386 C CG  . LEU D 1 522 ? -76.667 -1.257  19.173  1.00 83.77  ? 597  LEU D CG  1 
ATOM   12387 C CD1 . LEU D 1 522 ? -75.908 -1.476  17.872  1.00 89.98  ? 597  LEU D CD1 1 
ATOM   12388 C CD2 . LEU D 1 522 ? -77.289 0.135   19.211  1.00 68.28  ? 597  LEU D CD2 1 
ATOM   12389 N N   . GLU D 1 523 ? -79.669 -4.083  21.543  1.00 101.91 ? 598  GLU D N   1 
ATOM   12390 C CA  . GLU D 1 523 ? -80.667 -5.132  21.729  1.00 107.76 ? 598  GLU D CA  1 
ATOM   12391 C C   . GLU D 1 523 ? -82.034 -4.551  22.081  1.00 109.47 ? 598  GLU D C   1 
ATOM   12392 O O   . GLU D 1 523 ? -83.071 -5.164  21.784  1.00 115.45 ? 598  GLU D O   1 
ATOM   12393 C CB  . GLU D 1 523 ? -80.187 -6.097  22.817  1.00 119.37 ? 598  GLU D CB  1 
ATOM   12394 C CG  . GLU D 1 523 ? -81.169 -7.182  23.220  1.00 122.38 ? 598  GLU D CG  1 
ATOM   12395 C CD  . GLU D 1 523 ? -80.921 -7.679  24.633  1.00 142.90 ? 598  GLU D CD  1 
ATOM   12396 O OE1 . GLU D 1 523 ? -79.796 -7.486  25.140  1.00 156.97 ? 598  GLU D OE1 1 
ATOM   12397 O OE2 . GLU D 1 523 ? -81.851 -8.252  25.240  1.00 142.71 ? 598  GLU D OE2 1 
ATOM   12398 N N   . ILE D 1 524 ? -82.051 -3.367  22.701  1.00 104.11 ? 599  ILE D N   1 
ATOM   12399 C CA  . ILE D 1 524 ? -83.304 -2.730  23.101  1.00 96.41  ? 599  ILE D CA  1 
ATOM   12400 C C   . ILE D 1 524 ? -84.178 -2.447  21.886  1.00 100.25 ? 599  ILE D C   1 
ATOM   12401 O O   . ILE D 1 524 ? -85.408 -2.571  21.949  1.00 110.36 ? 599  ILE D O   1 
ATOM   12402 C CB  . ILE D 1 524 ? -83.015 -1.444  23.899  1.00 97.64  ? 599  ILE D CB  1 
ATOM   12403 C CG1 . ILE D 1 524 ? -82.291 -1.769  25.206  1.00 97.56  ? 599  ILE D CG1 1 
ATOM   12404 C CG2 . ILE D 1 524 ? -84.300 -0.687  24.183  1.00 87.81  ? 599  ILE D CG2 1 
ATOM   12405 C CD1 . ILE D 1 524 ? -83.077 -2.669  26.127  1.00 100.82 ? 599  ILE D CD1 1 
ATOM   12406 N N   . TYR D 1 525 ? -83.561 -2.052  20.767  1.00 106.79 ? 600  TYR D N   1 
ATOM   12407 C CA  . TYR D 1 525 ? -84.311 -1.814  19.534  1.00 106.08 ? 600  TYR D CA  1 
ATOM   12408 C C   . TYR D 1 525 ? -85.253 -2.968  19.221  1.00 102.96 ? 600  TYR D C   1 
ATOM   12409 O O   . TYR D 1 525 ? -86.449 -2.765  18.978  1.00 110.83 ? 600  TYR D O   1 
ATOM   12410 C CB  . TYR D 1 525 ? -83.352 -1.598  18.362  1.00 94.43  ? 600  TYR D CB  1 
ATOM   12411 C CG  . TYR D 1 525 ? -82.975 -0.160  18.114  1.00 81.66  ? 600  TYR D CG  1 
ATOM   12412 C CD1 . TYR D 1 525 ? -83.946 0.791   17.835  1.00 81.45  ? 600  TYR D CD1 1 
ATOM   12413 C CD2 . TYR D 1 525 ? -81.648 0.240   18.125  1.00 85.85  ? 600  TYR D CD2 1 
ATOM   12414 C CE1 . TYR D 1 525 ? -83.608 2.105   17.599  1.00 82.90  ? 600  TYR D CE1 1 
ATOM   12415 C CE2 . TYR D 1 525 ? -81.298 1.552   17.888  1.00 89.38  ? 600  TYR D CE2 1 
ATOM   12416 C CZ  . TYR D 1 525 ? -82.283 2.481   17.625  1.00 85.88  ? 600  TYR D CZ  1 
ATOM   12417 O OH  . TYR D 1 525 ? -81.944 3.791   17.386  1.00 90.79  ? 600  TYR D OH  1 
ATOM   12418 N N   . THR D 1 526 ? -84.729 -4.193  19.226  1.00 102.66 ? 601  THR D N   1 
ATOM   12419 C CA  . THR D 1 526 ? -85.542 -5.349  18.867  1.00 107.45 ? 601  THR D CA  1 
ATOM   12420 C C   . THR D 1 526 ? -86.440 -5.796  20.012  1.00 117.78 ? 601  THR D C   1 
ATOM   12421 O O   . THR D 1 526 ? -87.604 -6.147  19.784  1.00 117.50 ? 601  THR D O   1 
ATOM   12422 C CB  . THR D 1 526 ? -84.647 -6.499  18.414  1.00 102.77 ? 601  THR D CB  1 
ATOM   12423 O OG1 . THR D 1 526 ? -83.880 -6.980  19.525  1.00 114.65 ? 601  THR D OG1 1 
ATOM   12424 C CG2 . THR D 1 526 ? -83.715 -6.037  17.324  1.00 99.02  ? 601  THR D CG2 1 
ATOM   12425 N N   . THR D 1 527 ? -85.920 -5.805  21.244  1.00 112.49 ? 602  THR D N   1 
ATOM   12426 C CA  . THR D 1 527 ? -86.758 -6.192  22.374  1.00 107.71 ? 602  THR D CA  1 
ATOM   12427 C C   . THR D 1 527 ? -87.877 -5.182  22.594  1.00 108.00 ? 602  THR D C   1 
ATOM   12428 O O   . THR D 1 527 ? -88.993 -5.554  22.975  1.00 122.70 ? 602  THR D O   1 
ATOM   12429 C CB  . THR D 1 527 ? -85.919 -6.347  23.644  1.00 100.83 ? 602  THR D CB  1 
ATOM   12430 O OG1 . THR D 1 527 ? -85.343 -5.086  24.005  1.00 114.59 ? 602  THR D OG1 1 
ATOM   12431 C CG2 . THR D 1 527 ? -84.815 -7.376  23.448  1.00 103.42 ? 602  THR D CG2 1 
ATOM   12432 N N   . GLY D 1 528 ? -87.599 -3.903  22.357  1.00 106.46 ? 603  GLY D N   1 
ATOM   12433 C CA  . GLY D 1 528 ? -88.570 -2.837  22.486  1.00 106.86 ? 603  GLY D CA  1 
ATOM   12434 C C   . GLY D 1 528 ? -89.391 -2.555  21.247  1.00 114.64 ? 603  GLY D C   1 
ATOM   12435 O O   . GLY D 1 528 ? -90.196 -1.618  21.260  1.00 121.95 ? 603  GLY D O   1 
ATOM   12436 N N   . ARG D 1 529 ? -89.219 -3.343  20.181  1.00 110.03 ? 604  ARG D N   1 
ATOM   12437 C CA  . ARG D 1 529 ? -89.952 -3.160  18.926  1.00 118.74 ? 604  ARG D CA  1 
ATOM   12438 C C   . ARG D 1 529 ? -89.790 -1.737  18.393  1.00 120.13 ? 604  ARG D C   1 
ATOM   12439 O O   . ARG D 1 529 ? -90.741 -1.111  17.920  1.00 121.00 ? 604  ARG D O   1 
ATOM   12440 C CB  . ARG D 1 529 ? -91.431 -3.522  19.087  1.00 129.72 ? 604  ARG D CB  1 
ATOM   12441 C CG  . ARG D 1 529 ? -91.696 -4.674  20.047  1.00 127.79 ? 604  ARG D CG  1 
ATOM   12442 C CD  . ARG D 1 529 ? -91.059 -5.969  19.563  1.00 139.74 ? 604  ARG D CD  1 
ATOM   12443 N NE  . ARG D 1 529 ? -90.575 -6.783  20.672  1.00 162.98 ? 604  ARG D NE  1 
ATOM   12444 C CZ  . ARG D 1 529 ? -91.108 -7.940  21.042  1.00 154.98 ? 604  ARG D CZ  1 
ATOM   12445 N NH1 . ARG D 1 529 ? -92.153 -8.454  20.414  1.00 147.78 ? 604  ARG D NH1 1 
ATOM   12446 N NH2 . ARG D 1 529 ? -90.579 -8.599  22.070  1.00 147.94 ? 604  ARG D NH2 1 
ATOM   12447 N N   . LEU D 1 530 ? -88.562 -1.224  18.470  1.00 122.32 ? 605  LEU D N   1 
ATOM   12448 C CA  . LEU D 1 530 ? -88.238 0.126   18.033  1.00 115.56 ? 605  LEU D CA  1 
ATOM   12449 C C   . LEU D 1 530 ? -87.573 0.149   16.660  1.00 102.28 ? 605  LEU D C   1 
ATOM   12450 O O   . LEU D 1 530 ? -86.836 1.092   16.351  1.00 101.17 ? 605  LEU D O   1 
ATOM   12451 C CB  . LEU D 1 530 ? -87.342 0.810   19.066  1.00 107.93 ? 605  LEU D CB  1 
ATOM   12452 C CG  . LEU D 1 530 ? -87.876 0.864   20.500  1.00 96.03  ? 605  LEU D CG  1 
ATOM   12453 C CD1 . LEU D 1 530 ? -86.887 1.567   21.417  1.00 95.98  ? 605  LEU D CD1 1 
ATOM   12454 C CD2 . LEU D 1 530 ? -89.233 1.547   20.542  1.00 104.44 ? 605  LEU D CD2 1 
ATOM   12455 N N   . GLU D 1 531 ? -87.828 -0.866  15.828  1.00 94.18  ? 606  GLU D N   1 
ATOM   12456 C CA  . GLU D 1 531 ? -87.155 -0.966  14.536  1.00 96.70  ? 606  GLU D CA  1 
ATOM   12457 C C   . GLU D 1 531 ? -87.477 0.229   13.647  1.00 112.07 ? 606  GLU D C   1 
ATOM   12458 O O   . GLU D 1 531 ? -86.621 0.693   12.882  1.00 117.48 ? 606  GLU D O   1 
ATOM   12459 C CB  . GLU D 1 531 ? -87.553 -2.271  13.845  1.00 96.10  ? 606  GLU D CB  1 
ATOM   12460 C CG  . GLU D 1 531 ? -86.804 -3.500  14.334  1.00 103.24 ? 606  GLU D CG  1 
ATOM   12461 C CD  . GLU D 1 531 ? -87.463 -4.141  15.543  1.00 108.24 ? 606  GLU D CD  1 
ATOM   12462 O OE1 . GLU D 1 531 ? -87.716 -3.426  16.534  1.00 107.44 ? 606  GLU D OE1 1 
ATOM   12463 O OE2 . GLU D 1 531 ? -87.736 -5.359  15.501  1.00 120.45 ? 606  GLU D OE2 1 
ATOM   12464 N N   . LYS D 1 532 ? -88.714 0.731   13.726  1.00 111.98 ? 607  LYS D N   1 
ATOM   12465 C CA  . LYS D 1 532 ? -89.096 1.943   13.005  1.00 112.61 ? 607  LYS D CA  1 
ATOM   12466 C C   . LYS D 1 532 ? -88.129 3.087   13.283  1.00 112.86 ? 607  LYS D C   1 
ATOM   12467 O O   . LYS D 1 532 ? -87.659 3.765   12.359  1.00 116.07 ? 607  LYS D O   1 
ATOM   12468 C CB  . LYS D 1 532 ? -90.517 2.348   13.399  1.00 102.37 ? 607  LYS D CB  1 
ATOM   12469 C CG  . LYS D 1 532 ? -90.928 3.715   12.889  1.00 117.89 ? 607  LYS D CG  1 
ATOM   12470 C CD  . LYS D 1 532 ? -92.041 4.296   13.739  1.00 113.47 ? 607  LYS D CD  1 
ATOM   12471 C CE  . LYS D 1 532 ? -92.173 5.792   13.518  1.00 97.89  ? 607  LYS D CE  1 
ATOM   12472 N NZ  . LYS D 1 532 ? -93.231 6.403   14.371  1.00 99.33  ? 607  LYS D NZ  1 
ATOM   12473 N N   . HIS D 1 533 ? -87.831 3.323   14.561  1.00 100.62 ? 608  HIS D N   1 
ATOM   12474 C CA  . HIS D 1 533 ? -86.954 4.427   14.925  1.00 105.36 ? 608  HIS D CA  1 
ATOM   12475 C C   . HIS D 1 533 ? -85.529 4.190   14.443  1.00 103.27 ? 608  HIS D C   1 
ATOM   12476 O O   . HIS D 1 533 ? -84.838 5.141   14.059  1.00 101.57 ? 608  HIS D O   1 
ATOM   12477 C CB  . HIS D 1 533 ? -86.995 4.632   16.437  1.00 112.16 ? 608  HIS D CB  1 
ATOM   12478 C CG  . HIS D 1 533 ? -88.383 4.684   16.995  1.00 97.89  ? 608  HIS D CG  1 
ATOM   12479 N ND1 . HIS D 1 533 ? -89.250 5.725   16.741  1.00 91.55  ? 608  HIS D ND1 1 
ATOM   12480 C CD2 . HIS D 1 533 ? -89.060 3.813   17.780  1.00 83.29  ? 608  HIS D CD2 1 
ATOM   12481 C CE1 . HIS D 1 533 ? -90.398 5.498   17.354  1.00 94.44  ? 608  HIS D CE1 1 
ATOM   12482 N NE2 . HIS D 1 533 ? -90.309 4.344   17.991  1.00 93.18  ? 608  HIS D NE2 1 
ATOM   12483 N N   . LEU D 1 534 ? -85.078 2.932   14.441  1.00 98.08  ? 609  LEU D N   1 
ATOM   12484 C CA  . LEU D 1 534 ? -83.768 2.617   13.880  1.00 109.59 ? 609  LEU D CA  1 
ATOM   12485 C C   . LEU D 1 534 ? -83.716 2.940   12.393  1.00 107.96 ? 609  LEU D C   1 
ATOM   12486 O O   . LEU D 1 534 ? -82.724 3.494   11.904  1.00 99.31  ? 609  LEU D O   1 
ATOM   12487 C CB  . LEU D 1 534 ? -83.432 1.144   14.116  1.00 106.26 ? 609  LEU D CB  1 
ATOM   12488 C CG  . LEU D 1 534 ? -82.192 0.639   13.373  1.00 100.87 ? 609  LEU D CG  1 
ATOM   12489 C CD1 . LEU D 1 534 ? -80.918 0.899   14.172  1.00 100.77 ? 609  LEU D CD1 1 
ATOM   12490 C CD2 . LEU D 1 534 ? -82.328 -0.838  13.029  1.00 111.65 ? 609  LEU D CD2 1 
ATOM   12491 N N   . ASP D 1 535 ? -84.774 2.593   11.655  1.00 107.22 ? 610  ASP D N   1 
ATOM   12492 C CA  . ASP D 1 535 ? -84.811 2.900   10.228  1.00 107.05 ? 610  ASP D CA  1 
ATOM   12493 C C   . ASP D 1 535 ? -84.804 4.405   9.992   1.00 110.20 ? 610  ASP D C   1 
ATOM   12494 O O   . ASP D 1 535 ? -84.117 4.901   9.088   1.00 113.55 ? 610  ASP D O   1 
ATOM   12495 C CB  . ASP D 1 535 ? -86.042 2.262   9.586   1.00 104.68 ? 610  ASP D CB  1 
ATOM   12496 C CG  . ASP D 1 535 ? -86.086 0.761   9.776   1.00 117.75 ? 610  ASP D CG  1 
ATOM   12497 O OD1 . ASP D 1 535 ? -85.057 0.097   9.529   1.00 113.81 ? 610  ASP D OD1 1 
ATOM   12498 O OD2 . ASP D 1 535 ? -87.154 0.244   10.168  1.00 118.64 ? 610  ASP D OD2 1 
ATOM   12499 N N   . ALA D 1 536 ? -85.570 5.147   10.797  1.00 102.44 ? 611  ALA D N   1 
ATOM   12500 C CA  . ALA D 1 536 ? -85.575 6.601   10.674  1.00 106.84 ? 611  ALA D CA  1 
ATOM   12501 C C   . ALA D 1 536 ? -84.192 7.179   10.948  1.00 108.70 ? 611  ALA D C   1 
ATOM   12502 O O   . ALA D 1 536 ? -83.725 8.070   10.225  1.00 103.35 ? 611  ALA D O   1 
ATOM   12503 C CB  . ALA D 1 536 ? -86.613 7.204   11.621  1.00 110.93 ? 611  ALA D CB  1 
ATOM   12504 N N   . LEU D 1 537 ? -83.517 6.671   11.982  1.00 102.56 ? 612  LEU D N   1 
ATOM   12505 C CA  . LEU D 1 537 ? -82.168 7.126   12.301  1.00 107.06 ? 612  LEU D CA  1 
ATOM   12506 C C   . LEU D 1 537 ? -81.204 6.848   11.154  1.00 103.76 ? 612  LEU D C   1 
ATOM   12507 O O   . LEU D 1 537 ? -80.392 7.707   10.788  1.00 108.20 ? 612  LEU D O   1 
ATOM   12508 C CB  . LEU D 1 537 ? -81.689 6.449   13.585  1.00 97.52  ? 612  LEU D CB  1 
ATOM   12509 C CG  . LEU D 1 537 ? -80.213 6.621   13.945  1.00 87.99  ? 612  LEU D CG  1 
ATOM   12510 C CD1 . LEU D 1 537 ? -79.923 8.048   14.387  1.00 85.20  ? 612  LEU D CD1 1 
ATOM   12511 C CD2 . LEU D 1 537 ? -79.815 5.626   15.022  1.00 80.58  ? 612  LEU D CD2 1 
ATOM   12512 N N   . LEU D 1 538 ? -81.272 5.643   10.583  1.00 90.21  ? 613  LEU D N   1 
ATOM   12513 C CA  . LEU D 1 538 ? -80.396 5.288   9.469   1.00 95.55  ? 613  LEU D CA  1 
ATOM   12514 C C   . LEU D 1 538 ? -80.615 6.220   8.282   1.00 105.99 ? 613  LEU D C   1 
ATOM   12515 O O   . LEU D 1 538 ? -79.654 6.731   7.684   1.00 109.94 ? 613  LEU D O   1 
ATOM   12516 C CB  . LEU D 1 538 ? -80.641 3.833   9.064   1.00 91.38  ? 613  LEU D CB  1 
ATOM   12517 C CG  . LEU D 1 538 ? -80.218 2.744   10.051  1.00 88.92  ? 613  LEU D CG  1 
ATOM   12518 C CD1 . LEU D 1 538 ? -80.587 1.365   9.525   1.00 89.52  ? 613  LEU D CD1 1 
ATOM   12519 C CD2 . LEU D 1 538 ? -78.728 2.827   10.332  1.00 101.94 ? 613  LEU D CD2 1 
ATOM   12520 N N   . ARG D 1 539 ? -81.882 6.449   7.923   1.00 108.21 ? 614  ARG D N   1 
ATOM   12521 C CA  . ARG D 1 539 ? -82.172 7.324   6.791   1.00 118.47 ? 614  ARG D CA  1 
ATOM   12522 C C   . ARG D 1 539 ? -81.707 8.750   7.063   1.00 110.93 ? 614  ARG D C   1 
ATOM   12523 O O   . ARG D 1 539 ? -81.219 9.434   6.155   1.00 115.54 ? 614  ARG D O   1 
ATOM   12524 C CB  . ARG D 1 539 ? -83.665 7.287   6.454   1.00 114.27 ? 614  ARG D CB  1 
ATOM   12525 C CG  . ARG D 1 539 ? -84.109 5.971   5.823   1.00 127.22 ? 614  ARG D CG  1 
ATOM   12526 C CD  . ARG D 1 539 ? -85.627 5.834   5.669   1.00 144.85 ? 614  ARG D CD  1 
ATOM   12527 N NE  . ARG D 1 539 ? -86.355 5.665   6.922   1.00 145.31 ? 614  ARG D NE  1 
ATOM   12528 C CZ  . ARG D 1 539 ? -87.256 6.520   7.387   1.00 140.29 ? 614  ARG D CZ  1 
ATOM   12529 N NH1 . ARG D 1 539 ? -87.534 7.647   6.752   1.00 129.93 ? 614  ARG D NH1 1 
ATOM   12530 N NH2 . ARG D 1 539 ? -87.910 6.227   8.508   1.00 148.64 ? 614  ARG D NH2 1 
ATOM   12531 N N   . GLN D 1 540 ? -81.822 9.208   8.311   1.00 98.15  ? 615  GLN D N   1 
ATOM   12532 C CA  . GLN D 1 540 ? -81.369 10.557  8.637   1.00 104.24 ? 615  GLN D CA  1 
ATOM   12533 C C   . GLN D 1 540 ? -79.850 10.666  8.541   1.00 107.60 ? 615  GLN D C   1 
ATOM   12534 O O   . GLN D 1 540 ? -79.317 11.685  8.074   1.00 108.80 ? 615  GLN D O   1 
ATOM   12535 C CB  . GLN D 1 540 ? -81.851 10.938  10.036  1.00 99.36  ? 615  GLN D CB  1 
ATOM   12536 C CG  . GLN D 1 540 ? -81.717 12.412  10.363  1.00 113.95 ? 615  GLN D CG  1 
ATOM   12537 C CD  . GLN D 1 540 ? -82.563 13.287  9.462   1.00 117.65 ? 615  GLN D CD  1 
ATOM   12538 O OE1 . GLN D 1 540 ? -83.788 13.160  9.431   1.00 87.03  ? 615  GLN D OE1 1 
ATOM   12539 N NE2 . GLN D 1 540 ? -81.917 14.188  8.730   1.00 128.22 ? 615  GLN D NE2 1 
ATOM   12540 N N   . ILE D 1 541 ? -79.137 9.627   8.987   1.00 102.96 ? 616  ILE D N   1 
ATOM   12541 C CA  . ILE D 1 541 ? -77.682 9.602   8.843   1.00 105.64 ? 616  ILE D CA  1 
ATOM   12542 C C   . ILE D 1 541 ? -77.293 9.683   7.374   1.00 113.11 ? 616  ILE D C   1 
ATOM   12543 O O   . ILE D 1 541 ? -76.371 10.419  6.999   1.00 101.28 ? 616  ILE D O   1 
ATOM   12544 C CB  . ILE D 1 541 ? -77.090 8.347   9.514   1.00 91.50  ? 616  ILE D CB  1 
ATOM   12545 C CG1 . ILE D 1 541 ? -77.409 8.336   11.007  1.00 93.87  ? 616  ILE D CG1 1 
ATOM   12546 C CG2 . ILE D 1 541 ? -75.589 8.277   9.299   1.00 89.46  ? 616  ILE D CG2 1 
ATOM   12547 C CD1 . ILE D 1 541 ? -77.199 6.996   11.664  1.00 88.71  ? 616  ILE D CD1 1 
ATOM   12548 N N   . ARG D 1 542 ? -77.980 8.923   6.520   1.00 113.04 ? 617  ARG D N   1 
ATOM   12549 C CA  . ARG D 1 542 ? -77.682 8.976   5.090   1.00 103.10 ? 617  ARG D CA  1 
ATOM   12550 C C   . ARG D 1 542 ? -77.955 10.368  4.521   1.00 99.44  ? 617  ARG D C   1 
ATOM   12551 O O   . ARG D 1 542 ? -77.152 10.908  3.741   1.00 99.38  ? 617  ARG D O   1 
ATOM   12552 C CB  . ARG D 1 542 ? -78.499 7.906   4.371   1.00 92.67  ? 617  ARG D CB  1 
ATOM   12553 C CG  . ARG D 1 542 ? -78.161 6.499   4.854   1.00 99.11  ? 617  ARG D CG  1 
ATOM   12554 C CD  . ARG D 1 542 ? -79.089 5.450   4.273   1.00 101.76 ? 617  ARG D CD  1 
ATOM   12555 N NE  . ARG D 1 542 ? -78.934 5.301   2.833   1.00 110.21 ? 617  ARG D NE  1 
ATOM   12556 C CZ  . ARG D 1 542 ? -79.571 4.394   2.108   1.00 109.65 ? 617  ARG D CZ  1 
ATOM   12557 N NH1 . ARG D 1 542 ? -80.407 3.530   2.662   1.00 119.78 ? 617  ARG D NH1 1 
ATOM   12558 N NH2 . ARG D 1 542 ? -79.370 4.355   0.794   1.00 118.76 ? 617  ARG D NH2 1 
ATOM   12559 N N   . ASN D 1 543 ? -79.081 10.968  4.915   1.00 103.65 ? 618  ASN D N   1 
ATOM   12560 C CA  . ASN D 1 543 ? -79.391 12.335  4.509   1.00 113.46 ? 618  ASN D CA  1 
ATOM   12561 C C   . ASN D 1 543 ? -78.247 13.282  4.841   1.00 107.71 ? 618  ASN D C   1 
ATOM   12562 O O   . ASN D 1 543 ? -77.803 14.065  3.992   1.00 116.44 ? 618  ASN D O   1 
ATOM   12563 C CB  . ASN D 1 543 ? -80.676 12.808  5.190   1.00 115.58 ? 618  ASN D CB  1 
ATOM   12564 C CG  . ASN D 1 543 ? -81.885 12.001  4.779   1.00 132.50 ? 618  ASN D CG  1 
ATOM   12565 O OD1 . ASN D 1 543 ? -81.809 11.151  3.889   1.00 140.56 ? 618  ASN D OD1 1 
ATOM   12566 N ND2 . ASN D 1 543 ? -83.010 12.255  5.432   1.00 137.80 ? 618  ASN D ND2 1 
ATOM   12567 N N   . ILE D 1 544 ? -77.750 13.221  6.078   1.00 108.20 ? 619  ILE D N   1 
ATOM   12568 C CA  . ILE D 1 544 ? -76.702 14.160  6.467   1.00 112.27 ? 619  ILE D CA  1 
ATOM   12569 C C   . ILE D 1 544 ? -75.342 13.806  5.876   1.00 107.17 ? 619  ILE D C   1 
ATOM   12570 O O   . ILE D 1 544 ? -74.492 14.696  5.763   1.00 101.83 ? 619  ILE D O   1 
ATOM   12571 C CB  . ILE D 1 544 ? -76.585 14.295  7.996   1.00 114.00 ? 619  ILE D CB  1 
ATOM   12572 C CG1 . ILE D 1 544 ? -76.048 13.012  8.631   1.00 115.44 ? 619  ILE D CG1 1 
ATOM   12573 C CG2 . ILE D 1 544 ? -77.929 14.657  8.604   1.00 111.23 ? 619  ILE D CG2 1 
ATOM   12574 C CD1 . ILE D 1 544 ? -76.225 12.959  10.127  1.00 121.80 ? 619  ILE D CD1 1 
ATOM   12575 N N   . VAL D 1 545 ? -75.096 12.549  5.485   1.00 105.22 ? 620  VAL D N   1 
ATOM   12576 C CA  . VAL D 1 545 ? -73.849 12.307  4.759   1.00 99.31  ? 620  VAL D CA  1 
ATOM   12577 C C   . VAL D 1 545 ? -73.932 12.943  3.387   1.00 101.48 ? 620  VAL D C   1 
ATOM   12578 O O   . VAL D 1 545 ? -72.921 13.411  2.851   1.00 89.25  ? 620  VAL D O   1 
ATOM   12579 C CB  . VAL D 1 545 ? -73.464 10.813  4.628   1.00 82.06  ? 620  VAL D CB  1 
ATOM   12580 C CG1 . VAL D 1 545 ? -73.412 10.119  5.963   1.00 94.02  ? 620  VAL D CG1 1 
ATOM   12581 C CG2 . VAL D 1 545 ? -74.355 10.057  3.648   1.00 96.84  ? 620  VAL D CG2 1 
ATOM   12582 N N   . GLU D 1 546 ? -75.122 12.969  2.784   1.00 117.39 ? 621  GLU D N   1 
ATOM   12583 C CA  . GLU D 1 546 ? -75.228 13.625  1.483   1.00 102.61 ? 621  GLU D CA  1 
ATOM   12584 C C   . GLU D 1 546 ? -75.156 15.143  1.614   1.00 103.35 ? 621  GLU D C   1 
ATOM   12585 O O   . GLU D 1 546 ? -74.482 15.806  0.817   1.00 108.73 ? 621  GLU D O   1 
ATOM   12586 C CB  . GLU D 1 546 ? -76.509 13.208  0.768   1.00 94.25  ? 621  GLU D CB  1 
ATOM   12587 C CG  . GLU D 1 546 ? -76.635 11.714  0.572   1.00 104.21 ? 621  GLU D CG  1 
ATOM   12588 C CD  . GLU D 1 546 ? -78.060 11.245  0.689   1.00 121.34 ? 621  GLU D CD  1 
ATOM   12589 O OE1 . GLU D 1 546 ? -78.949 12.107  0.847   1.00 128.98 ? 621  GLU D OE1 1 
ATOM   12590 O OE2 . GLU D 1 546 ? -78.293 10.021  0.605   1.00 123.00 ? 621  GLU D OE2 1 
ATOM   12591 N N   . LYS D 1 547 ? -75.824 15.711  2.620   1.00 105.46 ? 622  LYS D N   1 
ATOM   12592 C CA  . LYS D 1 547 ? -75.892 17.167  2.728   1.00 104.95 ? 622  LYS D CA  1 
ATOM   12593 C C   . LYS D 1 547 ? -74.562 17.766  3.176   1.00 109.74 ? 622  LYS D C   1 
ATOM   12594 O O   . LYS D 1 547 ? -74.159 18.829  2.687   1.00 101.50 ? 622  LYS D O   1 
ATOM   12595 C CB  . LYS D 1 547 ? -77.009 17.569  3.691   1.00 92.34  ? 622  LYS D CB  1 
ATOM   12596 C CG  . LYS D 1 547 ? -78.401 17.162  3.235   1.00 106.33 ? 622  LYS D CG  1 
ATOM   12597 C CD  . LYS D 1 547 ? -79.475 17.953  3.966   1.00 127.47 ? 622  LYS D CD  1 
ATOM   12598 C CE  . LYS D 1 547 ? -79.459 17.661  5.457   1.00 115.07 ? 622  LYS D CE  1 
ATOM   12599 N NZ  . LYS D 1 547 ? -79.652 16.212  5.736   1.00 130.99 ? 622  LYS D NZ  1 
ATOM   12600 N N   . HIS D 1 548 ? -73.872 17.109  4.102   1.00 118.46 ? 623  HIS D N   1 
ATOM   12601 C CA  . HIS D 1 548 ? -72.684 17.676  4.722   1.00 109.68 ? 623  HIS D CA  1 
ATOM   12602 C C   . HIS D 1 548 ? -71.419 17.258  3.984   1.00 99.71  ? 623  HIS D C   1 
ATOM   12603 O O   . HIS D 1 548 ? -71.338 16.167  3.413   1.00 99.43  ? 623  HIS D O   1 
ATOM   12604 C CB  . HIS D 1 548 ? -72.583 17.244  6.186   1.00 99.07  ? 623  HIS D CB  1 
ATOM   12605 C CG  . HIS D 1 548 ? -73.521 17.971  7.097   1.00 93.86  ? 623  HIS D CG  1 
ATOM   12606 N ND1 . HIS D 1 548 ? -73.377 19.307  7.401   1.00 100.62 ? 623  HIS D ND1 1 
ATOM   12607 C CD2 . HIS D 1 548 ? -74.621 17.549  7.764   1.00 90.97  ? 623  HIS D CD2 1 
ATOM   12608 C CE1 . HIS D 1 548 ? -74.345 19.675  8.222   1.00 108.90 ? 623  HIS D CE1 1 
ATOM   12609 N NE2 . HIS D 1 548 ? -75.114 18.627  8.456   1.00 103.32 ? 623  HIS D NE2 1 
ATOM   12610 N N   . THR D 1 549 ? -70.430 18.150  3.998   1.00 95.18  ? 624  THR D N   1 
ATOM   12611 C CA  . THR D 1 549 ? -69.090 17.848  3.522   1.00 97.61  ? 624  THR D CA  1 
ATOM   12612 C C   . THR D 1 549 ? -68.044 17.989  4.618   1.00 104.57 ? 624  THR D C   1 
ATOM   12613 O O   . THR D 1 549 ? -66.858 17.754  4.359   1.00 103.99 ? 624  THR D O   1 
ATOM   12614 C CB  . THR D 1 549 ? -68.719 18.754  2.338   1.00 106.25 ? 624  THR D CB  1 
ATOM   12615 O OG1 . THR D 1 549 ? -68.610 20.111  2.785   1.00 115.62 ? 624  THR D OG1 1 
ATOM   12616 C CG2 . THR D 1 549 ? -69.773 18.664  1.246   1.00 109.13 ? 624  THR D CG2 1 
ATOM   12617 N N   . ASP D 1 550 ? -68.448 18.369  5.828   1.00 110.68 ? 625  ASP D N   1 
ATOM   12618 C CA  . ASP D 1 550 ? -67.510 18.502  6.932   1.00 104.57 ? 625  ASP D CA  1 
ATOM   12619 C C   . ASP D 1 550 ? -66.945 17.142  7.320   1.00 101.22 ? 625  ASP D C   1 
ATOM   12620 O O   . ASP D 1 550 ? -67.677 16.153  7.421   1.00 97.12  ? 625  ASP D O   1 
ATOM   12621 C CB  . ASP D 1 550 ? -68.199 19.155  8.130   1.00 95.87  ? 625  ASP D CB  1 
ATOM   12622 C CG  . ASP D 1 550 ? -67.370 19.079  9.391   1.00 96.35  ? 625  ASP D CG  1 
ATOM   12623 O OD1 . ASP D 1 550 ? -66.202 19.519  9.366   1.00 105.53 ? 625  ASP D OD1 1 
ATOM   12624 O OD2 . ASP D 1 550 ? -67.891 18.590  10.414  1.00 103.35 ? 625  ASP D OD2 1 
ATOM   12625 N N   . THR D 1 551 ? -65.627 17.097  7.533   1.00 99.18  ? 626  THR D N   1 
ATOM   12626 C CA  . THR D 1 551 ? -64.965 15.827  7.817   1.00 103.04 ? 626  THR D CA  1 
ATOM   12627 C C   . THR D 1 551 ? -65.451 15.227  9.131   1.00 94.71  ? 626  THR D C   1 
ATOM   12628 O O   . THR D 1 551 ? -65.559 14.002  9.260   1.00 89.37  ? 626  THR D O   1 
ATOM   12629 C CB  . THR D 1 551 ? -63.448 16.014  7.850   1.00 87.64  ? 626  THR D CB  1 
ATOM   12630 O OG1 . THR D 1 551 ? -63.031 16.782  6.714   1.00 101.60 ? 626  THR D OG1 1 
ATOM   12631 C CG2 . THR D 1 551 ? -62.747 14.663  7.819   1.00 88.69  ? 626  THR D CG2 1 
ATOM   12632 N N   . ASP D 1 552 ? -65.750 16.074  10.119  1.00 87.04  ? 627  ASP D N   1 
ATOM   12633 C CA  . ASP D 1 552 ? -66.206 15.563  11.408  1.00 86.08  ? 627  ASP D CA  1 
ATOM   12634 C C   . ASP D 1 552 ? -67.588 14.933  11.297  1.00 92.87  ? 627  ASP D C   1 
ATOM   12635 O O   . ASP D 1 552 ? -67.850 13.891  11.910  1.00 93.47  ? 627  ASP D O   1 
ATOM   12636 C CB  . ASP D 1 552 ? -66.201 16.680  12.448  1.00 85.27  ? 627  ASP D CB  1 
ATOM   12637 C CG  . ASP D 1 552 ? -64.872 17.398  12.520  1.00 94.78  ? 627  ASP D CG  1 
ATOM   12638 O OD1 . ASP D 1 552 ? -63.893 16.783  12.991  1.00 93.36  ? 627  ASP D OD1 1 
ATOM   12639 O OD2 . ASP D 1 552 ? -64.802 18.571  12.100  1.00 99.49  ? 627  ASP D OD2 1 
ATOM   12640 N N   . VAL D 1 553 ? -68.483 15.543  10.517  1.00 92.20  ? 628  VAL D N   1 
ATOM   12641 C CA  . VAL D 1 553 ? -69.810 14.965  10.320  1.00 84.88  ? 628  VAL D CA  1 
ATOM   12642 C C   . VAL D 1 553 ? -69.695 13.599  9.656   1.00 87.00  ? 628  VAL D C   1 
ATOM   12643 O O   . VAL D 1 553 ? -70.322 12.624  10.087  1.00 84.02  ? 628  VAL D O   1 
ATOM   12644 C CB  . VAL D 1 553 ? -70.699 15.912  9.494   1.00 87.29  ? 628  VAL D CB  1 
ATOM   12645 C CG1 . VAL D 1 553 ? -72.050 15.267  9.236   1.00 93.53  ? 628  VAL D CG1 1 
ATOM   12646 C CG2 . VAL D 1 553 ? -70.867 17.248  10.196  1.00 85.89  ? 628  VAL D CG2 1 
ATOM   12647 N N   . LEU D 1 554 ? -68.889 13.513  8.595   1.00 88.82  ? 629  LEU D N   1 
ATOM   12648 C CA  . LEU D 1 554 ? -68.736 12.258  7.868   1.00 90.32  ? 629  LEU D CA  1 
ATOM   12649 C C   . LEU D 1 554 ? -68.097 11.187  8.746   1.00 95.58  ? 629  LEU D C   1 
ATOM   12650 O O   . LEU D 1 554 ? -68.507 10.018  8.718   1.00 89.57  ? 629  LEU D O   1 
ATOM   12651 C CB  . LEU D 1 554 ? -67.901 12.496  6.610   1.00 81.53  ? 629  LEU D CB  1 
ATOM   12652 C CG  . LEU D 1 554 ? -68.467 13.510  5.612   1.00 82.23  ? 629  LEU D CG  1 
ATOM   12653 C CD1 . LEU D 1 554 ? -67.625 13.550  4.345   1.00 91.38  ? 629  LEU D CD1 1 
ATOM   12654 C CD2 . LEU D 1 554 ? -69.922 13.210  5.285   1.00 84.07  ? 629  LEU D CD2 1 
ATOM   12655 N N   . GLU D 1 555 ? -67.082 11.569  9.526   1.00 90.03  ? 630  GLU D N   1 
ATOM   12656 C CA  . GLU D 1 555 ? -66.479 10.646  10.482  1.00 84.21  ? 630  GLU D CA  1 
ATOM   12657 C C   . GLU D 1 555 ? -67.512 10.130  11.471  1.00 84.24  ? 630  GLU D C   1 
ATOM   12658 O O   . GLU D 1 555 ? -67.565 8.930   11.760  1.00 82.32  ? 630  GLU D O   1 
ATOM   12659 C CB  . GLU D 1 555 ? -65.338 11.331  11.231  1.00 79.68  ? 630  GLU D CB  1 
ATOM   12660 C CG  . GLU D 1 555 ? -64.936 10.596  12.500  1.00 98.27  ? 630  GLU D CG  1 
ATOM   12661 C CD  . GLU D 1 555 ? -63.598 11.042  13.041  1.00 93.62  ? 630  GLU D CD  1 
ATOM   12662 O OE1 . GLU D 1 555 ? -63.065 12.050  12.537  1.00 84.18  ? 630  GLU D OE1 1 
ATOM   12663 O OE2 . GLU D 1 555 ? -63.084 10.388  13.974  1.00 91.14  ? 630  GLU D OE2 1 
ATOM   12664 N N   . ALA D 1 556 ? -68.331 11.031  12.019  1.00 78.75  ? 631  ALA D N   1 
ATOM   12665 C CA  . ALA D 1 556 ? -69.339 10.618  12.987  1.00 72.58  ? 631  ALA D CA  1 
ATOM   12666 C C   . ALA D 1 556 ? -70.361 9.685   12.353  1.00 77.30  ? 631  ALA D C   1 
ATOM   12667 O O   . ALA D 1 556 ? -70.818 8.731   12.991  1.00 69.30  ? 631  ALA D O   1 
ATOM   12668 C CB  . ALA D 1 556 ? -70.023 11.847  13.585  1.00 77.49  ? 631  ALA D CB  1 
ATOM   12669 N N   . CYS D 1 557 ? -70.720 9.933   11.092  1.00 81.99  ? 632  CYS D N   1 
ATOM   12670 C CA  . CYS D 1 557 ? -71.660 9.050   10.406  1.00 85.20  ? 632  CYS D CA  1 
ATOM   12671 C C   . CYS D 1 557 ? -71.066 7.661   10.214  1.00 81.96  ? 632  CYS D C   1 
ATOM   12672 O O   . CYS D 1 557 ? -71.729 6.646   10.467  1.00 82.49  ? 632  CYS D O   1 
ATOM   12673 C CB  . CYS D 1 557 ? -72.064 9.645   9.059   1.00 72.73  ? 632  CYS D CB  1 
ATOM   12674 S SG  . CYS D 1 557 ? -72.833 11.276  9.129   1.00 88.79  ? 632  CYS D SG  1 
ATOM   12675 N N   . SER D 1 558 ? -69.813 7.597   9.757   1.00 76.23  ? 633  SER D N   1 
ATOM   12676 C CA  . SER D 1 558 ? -69.164 6.302   9.580   1.00 81.03  ? 633  SER D CA  1 
ATOM   12677 C C   . SER D 1 558 ? -69.035 5.567   10.909  1.00 86.18  ? 633  SER D C   1 
ATOM   12678 O O   . SER D 1 558 ? -69.255 4.352   10.981  1.00 90.77  ? 633  SER D O   1 
ATOM   12679 C CB  . SER D 1 558 ? -67.793 6.484   8.933   1.00 75.57  ? 633  SER D CB  1 
ATOM   12680 O OG  . SER D 1 558 ? -67.159 5.232   8.736   1.00 78.22  ? 633  SER D OG  1 
ATOM   12681 N N   . LYS D 1 559 ? -68.695 6.294   11.976  1.00 83.50  ? 634  LYS D N   1 
ATOM   12682 C CA  . LYS D 1 559 ? -68.536 5.672   13.285  1.00 78.02  ? 634  LYS D CA  1 
ATOM   12683 C C   . LYS D 1 559 ? -69.870 5.165   13.817  1.00 93.60  ? 634  LYS D C   1 
ATOM   12684 O O   . LYS D 1 559 ? -69.939 4.084   14.414  1.00 94.85  ? 634  LYS D O   1 
ATOM   12685 C CB  . LYS D 1 559 ? -67.920 6.680   14.260  1.00 81.94  ? 634  LYS D CB  1 
ATOM   12686 C CG  . LYS D 1 559 ? -66.434 6.977   14.043  1.00 87.48  ? 634  LYS D CG  1 
ATOM   12687 C CD  . LYS D 1 559 ? -65.543 5.743   14.075  1.00 103.26 ? 634  LYS D CD  1 
ATOM   12688 C CE  . LYS D 1 559 ? -65.784 4.893   15.312  1.00 123.39 ? 634  LYS D CE  1 
ATOM   12689 N NZ  . LYS D 1 559 ? -65.459 3.464   15.062  1.00 127.30 ? 634  LYS D NZ  1 
ATOM   12690 N N   . THR D 1 560 ? -70.942 5.936   13.609  1.00 84.11  ? 635  THR D N   1 
ATOM   12691 C CA  . THR D 1 560 ? -72.268 5.507   14.035  1.00 73.65  ? 635  THR D CA  1 
ATOM   12692 C C   . THR D 1 560 ? -72.708 4.267   13.273  1.00 84.49  ? 635  THR D C   1 
ATOM   12693 O O   . THR D 1 560 ? -73.259 3.328   13.862  1.00 88.41  ? 635  THR D O   1 
ATOM   12694 C CB  . THR D 1 560 ? -73.270 6.645   13.833  1.00 74.47  ? 635  THR D CB  1 
ATOM   12695 O OG1 . THR D 1 560 ? -72.796 7.826   14.492  1.00 74.28  ? 635  THR D OG1 1 
ATOM   12696 C CG2 . THR D 1 560 ? -74.634 6.266   14.391  1.00 73.27  ? 635  THR D CG2 1 
ATOM   12697 N N   . TYR D 1 561 ? -72.465 4.240   11.961  1.00 82.58  ? 636  TYR D N   1 
ATOM   12698 C CA  . TYR D 1 561 ? -72.824 3.065   11.175  1.00 87.07  ? 636  TYR D CA  1 
ATOM   12699 C C   . TYR D 1 561 ? -72.005 1.853   11.599  1.00 78.35  ? 636  TYR D C   1 
ATOM   12700 O O   . TYR D 1 561 ? -72.512 0.726   11.610  1.00 80.06  ? 636  TYR D O   1 
ATOM   12701 C CB  . TYR D 1 561 ? -72.643 3.352   9.685   1.00 81.15  ? 636  TYR D CB  1 
ATOM   12702 C CG  . TYR D 1 561 ? -73.951 3.447   8.931   1.00 98.42  ? 636  TYR D CG  1 
ATOM   12703 C CD1 . TYR D 1 561 ? -74.722 2.315   8.695   1.00 98.53  ? 636  TYR D CD1 1 
ATOM   12704 C CD2 . TYR D 1 561 ? -74.418 4.669   8.460   1.00 89.52  ? 636  TYR D CD2 1 
ATOM   12705 C CE1 . TYR D 1 561 ? -75.918 2.396   8.009   1.00 102.28 ? 636  TYR D CE1 1 
ATOM   12706 C CE2 . TYR D 1 561 ? -75.615 4.759   7.772   1.00 89.18  ? 636  TYR D CE2 1 
ATOM   12707 C CZ  . TYR D 1 561 ? -76.360 3.620   7.549   1.00 106.28 ? 636  TYR D CZ  1 
ATOM   12708 O OH  . TYR D 1 561 ? -77.551 3.703   6.864   1.00 115.14 ? 636  TYR D OH  1 
ATOM   12709 N N   . HIS D 1 562 ? -70.738 2.066   11.960  1.00 79.18  ? 637  HIS D N   1 
ATOM   12710 C CA  . HIS D 1 562 ? -69.920 0.968   12.466  1.00 87.26  ? 637  HIS D CA  1 
ATOM   12711 C C   . HIS D 1 562 ? -70.463 0.435   13.786  1.00 81.64  ? 637  HIS D C   1 
ATOM   12712 O O   . HIS D 1 562 ? -70.544 -0.782  13.989  1.00 83.00  ? 637  HIS D O   1 
ATOM   12713 C CB  . HIS D 1 562 ? -68.471 1.419   12.633  1.00 82.71  ? 637  HIS D CB  1 
ATOM   12714 C CG  . HIS D 1 562 ? -67.589 0.376   13.243  1.00 78.77  ? 637  HIS D CG  1 
ATOM   12715 N ND1 . HIS D 1 562 ? -66.680 0.661   14.239  1.00 86.62  ? 637  HIS D ND1 1 
ATOM   12716 C CD2 . HIS D 1 562 ? -67.494 -0.955  13.017  1.00 80.16  ? 637  HIS D CD2 1 
ATOM   12717 C CE1 . HIS D 1 562 ? -66.052 -0.447  14.589  1.00 93.02  ? 637  HIS D CE1 1 
ATOM   12718 N NE2 . HIS D 1 562 ? -66.528 -1.443  13.864  1.00 92.84  ? 637  HIS D NE2 1 
ATOM   12719 N N   . ALA D 1 563 ? -70.821 1.335   14.704  1.00 76.38  ? 638  ALA D N   1 
ATOM   12720 C CA  . ALA D 1 563 ? -71.392 0.901   15.974  1.00 83.06  ? 638  ALA D CA  1 
ATOM   12721 C C   . ALA D 1 563 ? -72.698 0.148   15.758  1.00 87.32  ? 638  ALA D C   1 
ATOM   12722 O O   . ALA D 1 563 ? -72.987 -0.827  16.462  1.00 81.53  ? 638  ALA D O   1 
ATOM   12723 C CB  . ALA D 1 563 ? -71.610 2.104   16.892  1.00 67.88  ? 638  ALA D CB  1 
ATOM   12724 N N   . LEU D 1 564 ? -73.492 0.575   14.775  1.00 83.12  ? 639  LEU D N   1 
ATOM   12725 C CA  . LEU D 1 564 ? -74.777 -0.070  14.531  1.00 77.28  ? 639  LEU D CA  1 
ATOM   12726 C C   . LEU D 1 564 ? -74.615 -1.400  13.799  1.00 83.92  ? 639  LEU D C   1 
ATOM   12727 O O   . LEU D 1 564 ? -75.441 -2.303  13.975  1.00 88.65  ? 639  LEU D O   1 
ATOM   12728 C CB  . LEU D 1 564 ? -75.689 0.873   13.748  1.00 82.77  ? 639  LEU D CB  1 
ATOM   12729 C CG  . LEU D 1 564 ? -76.207 2.091   14.516  1.00 79.77  ? 639  LEU D CG  1 
ATOM   12730 C CD1 . LEU D 1 564 ? -76.902 3.065   13.580  1.00 81.64  ? 639  LEU D CD1 1 
ATOM   12731 C CD2 . LEU D 1 564 ? -77.147 1.656   15.628  1.00 74.43  ? 639  LEU D CD2 1 
ATOM   12732 N N   . CYS D 1 565 ? -73.566 -1.542  12.985  1.00 86.38  ? 640  CYS D N   1 
ATOM   12733 C CA  . CYS D 1 565 ? -73.316 -2.777  12.232  1.00 88.86  ? 640  CYS D CA  1 
ATOM   12734 C C   . CYS D 1 565 ? -72.545 -3.775  13.095  1.00 96.20  ? 640  CYS D C   1 
ATOM   12735 O O   . CYS D 1 565 ? -71.350 -4.020  12.917  1.00 113.04 ? 640  CYS D O   1 
ATOM   12736 C CB  . CYS D 1 565 ? -72.561 -2.483  10.942  1.00 87.32  ? 640  CYS D CB  1 
ATOM   12737 S SG  . CYS D 1 565 ? -73.449 -1.535  9.701   1.00 102.79 ? 640  CYS D SG  1 
ATOM   12738 N N   . ASN D 1 566 ? -73.265 -4.372  14.038  1.00 80.59  ? 641  ASN D N   1 
ATOM   12739 C CA  . ASN D 1 566 ? -72.716 -5.415  14.894  1.00 92.57  ? 641  ASN D CA  1 
ATOM   12740 C C   . ASN D 1 566 ? -73.484 -6.705  14.652  1.00 98.59  ? 641  ASN D C   1 
ATOM   12741 O O   . ASN D 1 566 ? -74.687 -6.772  14.929  1.00 114.67 ? 641  ASN D O   1 
ATOM   12742 C CB  . ASN D 1 566 ? -72.786 -5.014  16.367  1.00 97.73  ? 641  ASN D CB  1 
ATOM   12743 C CG  . ASN D 1 566 ? -71.875 -5.852  17.238  1.00 105.37 ? 641  ASN D CG  1 
ATOM   12744 O OD1 . ASN D 1 566 ? -71.121 -6.688  16.740  1.00 113.52 ? 641  ASN D OD1 1 
ATOM   12745 N ND2 . ASN D 1 566 ? -71.941 -5.637  18.547  1.00 103.75 ? 641  ASN D ND2 1 
ATOM   12746 N N   . GLU D 1 567 ? -72.788 -7.727  14.139  1.00 98.94  ? 642  GLU D N   1 
ATOM   12747 C CA  . GLU D 1 567 ? -73.410 -9.034  13.939  1.00 110.26 ? 642  GLU D CA  1 
ATOM   12748 C C   . GLU D 1 567 ? -73.936 -9.634  15.236  1.00 111.49 ? 642  GLU D C   1 
ATOM   12749 O O   . GLU D 1 567 ? -74.852 -10.463 15.195  1.00 124.51 ? 642  GLU D O   1 
ATOM   12750 C CB  . GLU D 1 567 ? -72.417 -10.007 13.294  1.00 101.85 ? 642  GLU D CB  1 
ATOM   12751 C CG  . GLU D 1 567 ? -71.881 -9.570  11.941  1.00 102.10 ? 642  GLU D CG  1 
ATOM   12752 C CD  . GLU D 1 567 ? -70.550 -8.861  12.042  1.00 121.83 ? 642  GLU D CD  1 
ATOM   12753 O OE1 . GLU D 1 567 ? -69.953 -8.865  13.140  1.00 132.02 ? 642  GLU D OE1 1 
ATOM   12754 O OE2 . GLU D 1 567 ? -70.101 -8.299  11.020  1.00 112.81 ? 642  GLU D OE2 1 
ATOM   12755 N N   . GLU D 1 568 ? -73.375 -9.239  16.381  1.00 94.37  ? 643  GLU D N   1 
ATOM   12756 C CA  . GLU D 1 568 ? -73.875 -9.733  17.659  1.00 93.52  ? 643  GLU D CA  1 
ATOM   12757 C C   . GLU D 1 568 ? -75.282 -9.230  17.947  1.00 104.50 ? 643  GLU D C   1 
ATOM   12758 O O   . GLU D 1 568 ? -76.050 -9.909  18.637  1.00 121.75 ? 643  GLU D O   1 
ATOM   12759 C CB  . GLU D 1 568 ? -72.923 -9.322  18.782  1.00 106.35 ? 643  GLU D CB  1 
ATOM   12760 C CG  . GLU D 1 568 ? -71.479 -9.714  18.527  1.00 120.30 ? 643  GLU D CG  1 
ATOM   12761 C CD  . GLU D 1 568 ? -70.516 -9.074  19.507  1.00 131.59 ? 643  GLU D CD  1 
ATOM   12762 O OE1 . GLU D 1 568 ? -70.540 -9.441  20.701  1.00 134.92 ? 643  GLU D OE1 1 
ATOM   12763 O OE2 . GLU D 1 568 ? -69.730 -8.203  19.077  1.00 134.39 ? 643  GLU D OE2 1 
ATOM   12764 N N   . PHE D 1 569 ? -75.636 -8.053  17.441  1.00 106.75 ? 644  PHE D N   1 
ATOM   12765 C CA  . PHE D 1 569 ? -76.984 -7.524  17.589  1.00 112.86 ? 644  PHE D CA  1 
ATOM   12766 C C   . PHE D 1 569 ? -77.842 -7.919  16.394  1.00 110.95 ? 644  PHE D C   1 
ATOM   12767 O O   . PHE D 1 569 ? -77.370 -7.942  15.253  1.00 115.14 ? 644  PHE D O   1 
ATOM   12768 C CB  . PHE D 1 569 ? -76.953 -6.003  17.736  1.00 103.25 ? 644  PHE D CB  1 
ATOM   12769 C CG  . PHE D 1 569 ? -76.370 -5.537  19.037  1.00 101.92 ? 644  PHE D CG  1 
ATOM   12770 C CD1 . PHE D 1 569 ? -76.991 -5.848  20.234  1.00 112.11 ? 644  PHE D CD1 1 
ATOM   12771 C CD2 . PHE D 1 569 ? -75.197 -4.802  19.064  1.00 101.89 ? 644  PHE D CD2 1 
ATOM   12772 C CE1 . PHE D 1 569 ? -76.458 -5.426  21.435  1.00 121.40 ? 644  PHE D CE1 1 
ATOM   12773 C CE2 . PHE D 1 569 ? -74.660 -4.378  20.260  1.00 112.16 ? 644  PHE D CE2 1 
ATOM   12774 C CZ  . PHE D 1 569 ? -75.290 -4.691  21.448  1.00 118.01 ? 644  PHE D CZ  1 
ATOM   12775 N N   . THR D 1 570 ? -79.116 -8.211  16.664  1.00 107.02 ? 645  THR D N   1 
ATOM   12776 C CA  . THR D 1 570 ? -80.012 -8.690  15.617  1.00 99.85  ? 645  THR D CA  1 
ATOM   12777 C C   . THR D 1 570 ? -80.368 -7.616  14.594  1.00 106.26 ? 645  THR D C   1 
ATOM   12778 O O   . THR D 1 570 ? -80.773 -7.961  13.480  1.00 112.28 ? 645  THR D O   1 
ATOM   12779 C CB  . THR D 1 570 ? -81.290 -9.253  16.238  1.00 86.55  ? 645  THR D CB  1 
ATOM   12780 O OG1 . THR D 1 570 ? -81.846 -8.296  17.149  1.00 88.95  ? 645  THR D OG1 1 
ATOM   12781 C CG2 . THR D 1 570 ? -80.975 -10.558 16.991  1.00 86.40  ? 645  THR D CG2 1 
ATOM   12782 N N   . ILE D 1 571 ? -80.225 -6.332  14.934  1.00 96.58  ? 646  ILE D N   1 
ATOM   12783 C CA  . ILE D 1 571 ? -80.484 -5.270  13.965  1.00 107.62 ? 646  ILE D CA  1 
ATOM   12784 C C   . ILE D 1 571 ? -79.491 -5.265  12.814  1.00 112.49 ? 646  ILE D C   1 
ATOM   12785 O O   . ILE D 1 571 ? -79.746 -4.601  11.798  1.00 122.48 ? 646  ILE D O   1 
ATOM   12786 C CB  . ILE D 1 571 ? -80.471 -3.878  14.633  1.00 102.69 ? 646  ILE D CB  1 
ATOM   12787 C CG1 . ILE D 1 571 ? -79.064 -3.523  15.116  1.00 97.49  ? 646  ILE D CG1 1 
ATOM   12788 C CG2 . ILE D 1 571 ? -81.457 -3.810  15.775  1.00 105.11 ? 646  ILE D CG2 1 
ATOM   12789 C CD1 . ILE D 1 571 ? -78.940 -2.103  15.623  1.00 92.26  ? 646  ILE D CD1 1 
ATOM   12790 N N   . PHE D 1 572 ? -78.380 -5.999  12.949  1.00 107.52 ? 647  PHE D N   1 
ATOM   12791 C CA  . PHE D 1 572 ? -77.275 -5.965  11.995  1.00 106.68 ? 647  PHE D CA  1 
ATOM   12792 C C   . PHE D 1 572 ? -77.761 -5.954  10.553  1.00 114.94 ? 647  PHE D C   1 
ATOM   12793 O O   . PHE D 1 572 ? -77.533 -4.984  9.817   1.00 108.55 ? 647  PHE D O   1 
ATOM   12794 C CB  . PHE D 1 572 ? -76.350 -7.164  12.224  1.00 98.42  ? 647  PHE D CB  1 
ATOM   12795 C CG  . PHE D 1 572 ? -75.237 -7.265  11.219  1.00 109.29 ? 647  PHE D CG  1 
ATOM   12796 C CD1 . PHE D 1 572 ? -74.329 -6.229  11.074  1.00 114.29 ? 647  PHE D CD1 1 
ATOM   12797 C CD2 . PHE D 1 572 ? -75.103 -8.383  10.411  1.00 112.88 ? 647  PHE D CD2 1 
ATOM   12798 C CE1 . PHE D 1 572 ? -73.304 -6.306  10.151  1.00 110.11 ? 647  PHE D CE1 1 
ATOM   12799 C CE2 . PHE D 1 572 ? -74.080 -8.466  9.483   1.00 109.66 ? 647  PHE D CE2 1 
ATOM   12800 C CZ  . PHE D 1 572 ? -73.179 -7.426  9.354   1.00 111.56 ? 647  PHE D CZ  1 
ATOM   12801 N N   . ASN D 1 573 ? -78.444 -7.034  10.155  1.00 119.62 ? 648  ASN D N   1 
ATOM   12802 C CA  . ASN D 1 573 ? -79.051 -7.145  8.833   1.00 119.93 ? 648  ASN D CA  1 
ATOM   12803 C C   . ASN D 1 573 ? -79.568 -5.801  8.348   1.00 113.08 ? 648  ASN D C   1 
ATOM   12804 O O   . ASN D 1 573 ? -79.032 -5.225  7.392   1.00 112.55 ? 648  ASN D O   1 
ATOM   12805 C CB  . ASN D 1 573 ? -80.195 -8.168  8.855   1.00 122.25 ? 648  ASN D CB  1 
ATOM   12806 C CG  . ASN D 1 573 ? -79.728 -9.565  9.208   1.00 136.32 ? 648  ASN D CG  1 
ATOM   12807 O OD1 . ASN D 1 573 ? -80.148 -10.138 10.214  1.00 135.91 ? 648  ASN D OD1 1 
ATOM   12808 N ND2 . ASN D 1 573 ? -78.856 -10.122 8.377   1.00 130.40 ? 648  ASN D ND2 1 
ATOM   12809 N N   . ARG D 1 574 ? -80.580 -5.270  9.044   1.00 107.33 ? 649  ARG D N   1 
ATOM   12810 C CA  . ARG D 1 574 ? -81.174 -3.997  8.657   1.00 111.29 ? 649  ARG D CA  1 
ATOM   12811 C C   . ARG D 1 574 ? -80.092 -2.968  8.378   1.00 116.82 ? 649  ARG D C   1 
ATOM   12812 O O   . ARG D 1 574 ? -79.909 -2.530  7.233   1.00 113.93 ? 649  ARG D O   1 
ATOM   12813 C CB  . ARG D 1 574 ? -82.124 -3.504  9.751   1.00 108.65 ? 649  ARG D CB  1 
ATOM   12814 C CG  . ARG D 1 574 ? -82.972 -4.605  10.363  1.00 125.31 ? 649  ARG D CG  1 
ATOM   12815 C CD  . ARG D 1 574 ? -83.899 -4.074  11.447  1.00 125.66 ? 649  ARG D CD  1 
ATOM   12816 N NE  . ARG D 1 574 ? -84.829 -3.074  10.935  1.00 115.86 ? 649  ARG D NE  1 
ATOM   12817 C CZ  . ARG D 1 574 ? -86.120 -3.292  10.722  1.00 112.45 ? 649  ARG D CZ  1 
ATOM   12818 N NH1 . ARG D 1 574 ? -86.677 -4.464  10.982  1.00 114.80 ? 649  ARG D NH1 1 
ATOM   12819 N NH2 . ARG D 1 574 ? -86.871 -2.310  10.231  1.00 113.19 ? 649  ARG D NH2 1 
ATOM   12820 N N   . VAL D 1 575 ? -79.310 -2.635  9.409   1.00 119.70 ? 650  VAL D N   1 
ATOM   12821 C CA  . VAL D 1 575 ? -78.270 -1.626  9.252   1.00 113.04 ? 650  VAL D CA  1 
ATOM   12822 C C   . VAL D 1 575 ? -77.373 -1.993  8.081   1.00 112.02 ? 650  VAL D C   1 
ATOM   12823 O O   . VAL D 1 575 ? -77.161 -1.185  7.164   1.00 111.79 ? 650  VAL D O   1 
ATOM   12824 C CB  . VAL D 1 575 ? -77.472 -1.472  10.558  1.00 106.65 ? 650  VAL D CB  1 
ATOM   12825 C CG1 . VAL D 1 575 ? -76.532 -0.280  10.469  1.00 100.84 ? 650  VAL D CG1 1 
ATOM   12826 C CG2 . VAL D 1 575 ? -78.419 -1.349  11.746  1.00 97.80  ? 650  VAL D CG2 1 
ATOM   12827 N N   . ASP D 1 576 ? -76.907 -3.249  8.056   1.00 110.70 ? 651  ASP D N   1 
ATOM   12828 C CA  . ASP D 1 576 ? -76.049 -3.710  6.970   1.00 112.57 ? 651  ASP D CA  1 
ATOM   12829 C C   . ASP D 1 576 ? -76.636 -3.317  5.626   1.00 103.44 ? 651  ASP D C   1 
ATOM   12830 O O   . ASP D 1 576 ? -75.992 -2.605  4.842   1.00 99.09  ? 651  ASP D O   1 
ATOM   12831 C CB  . ASP D 1 576 ? -75.855 -5.226  7.056   1.00 105.80 ? 651  ASP D CB  1 
ATOM   12832 C CG  . ASP D 1 576 ? -74.848 -5.747  6.044   1.00 108.99 ? 651  ASP D CG  1 
ATOM   12833 O OD1 . ASP D 1 576 ? -74.170 -4.924  5.395   1.00 125.74 ? 651  ASP D OD1 1 
ATOM   12834 O OD2 . ASP D 1 576 ? -74.730 -6.982  5.903   1.00 105.66 ? 651  ASP D OD2 1 
ATOM   12835 N N   . ILE D 1 577 ? -77.893 -3.708  5.383   1.00 110.40 ? 652  ILE D N   1 
ATOM   12836 C CA  . ILE D 1 577 ? -78.556 -3.364  4.126   1.00 110.07 ? 652  ILE D CA  1 
ATOM   12837 C C   . ILE D 1 577 ? -78.398 -1.876  3.850   1.00 106.04 ? 652  ILE D C   1 
ATOM   12838 O O   . ILE D 1 577 ? -77.743 -1.472  2.878   1.00 113.58 ? 652  ILE D O   1 
ATOM   12839 C CB  . ILE D 1 577 ? -80.036 -3.780  4.160   1.00 94.90  ? 652  ILE D CB  1 
ATOM   12840 C CG1 . ILE D 1 577 ? -80.148 -5.304  4.187   1.00 93.63  ? 652  ILE D CG1 1 
ATOM   12841 C CG2 . ILE D 1 577 ? -80.773 -3.228  2.947   1.00 98.82  ? 652  ILE D CG2 1 
ATOM   12842 C CD1 . ILE D 1 577 ? -81.540 -5.812  4.450   1.00 103.44 ? 652  ILE D CD1 1 
ATOM   12843 N N   . SER D 1 578 ? -78.929 -1.044  4.754   1.00 105.88 ? 653  SER D N   1 
ATOM   12844 C CA  . SER D 1 578 ? -78.840 0.399   4.569   1.00 105.07 ? 653  SER D CA  1 
ATOM   12845 C C   . SER D 1 578 ? -77.409 0.807   4.261   1.00 105.08 ? 653  SER D C   1 
ATOM   12846 O O   . SER D 1 578 ? -77.149 1.470   3.247   1.00 106.08 ? 653  SER D O   1 
ATOM   12847 C CB  . SER D 1 578 ? -79.366 1.132   5.806   1.00 102.99 ? 653  SER D CB  1 
ATOM   12848 O OG  . SER D 1 578 ? -78.587 0.845   6.952   1.00 114.27 ? 653  SER D OG  1 
ATOM   12849 N N   . ARG D 1 579 ? -76.457 0.338   5.077   1.00 109.74 ? 654  ARG D N   1 
ATOM   12850 C CA  . ARG D 1 579 ? -75.061 0.694   4.859   1.00 111.39 ? 654  ARG D CA  1 
ATOM   12851 C C   . ARG D 1 579 ? -74.676 0.423   3.414   1.00 112.61 ? 654  ARG D C   1 
ATOM   12852 O O   . ARG D 1 579 ? -74.354 1.350   2.657   1.00 113.73 ? 654  ARG D O   1 
ATOM   12853 C CB  . ARG D 1 579 ? -74.141 -0.074  5.815   1.00 108.19 ? 654  ARG D CB  1 
ATOM   12854 C CG  . ARG D 1 579 ? -72.765 0.577   5.940   1.00 98.91  ? 654  ARG D CG  1 
ATOM   12855 C CD  . ARG D 1 579 ? -71.593 -0.404  5.997   1.00 80.33  ? 654  ARG D CD  1 
ATOM   12856 N NE  . ARG D 1 579 ? -71.740 -1.467  6.984   1.00 86.43  ? 654  ARG D NE  1 
ATOM   12857 C CZ  . ARG D 1 579 ? -71.987 -2.735  6.683   1.00 96.92  ? 654  ARG D CZ  1 
ATOM   12858 N NH1 . ARG D 1 579 ? -72.133 -3.132  5.429   1.00 97.65  ? 654  ARG D NH1 1 
ATOM   12859 N NH2 . ARG D 1 579 ? -72.078 -3.629  7.664   1.00 99.10  ? 654  ARG D NH2 1 
ATOM   12860 N N   . SER D 1 580 ? -74.802 -0.842  2.992   1.00 111.00 ? 655  SER D N   1 
ATOM   12861 C CA  . SER D 1 580 ? -74.415 -1.210  1.634   1.00 107.93 ? 655  SER D CA  1 
ATOM   12862 C C   . SER D 1 580 ? -75.095 -0.297  0.629   1.00 101.78 ? 655  SER D C   1 
ATOM   12863 O O   . SER D 1 580 ? -74.439 0.283   -0.247  1.00 106.58 ? 655  SER D O   1 
ATOM   12864 C CB  . SER D 1 580 ? -74.763 -2.674  1.356   1.00 87.23  ? 655  SER D CB  1 
ATOM   12865 O OG  . SER D 1 580 ? -76.162 -2.893  1.396   1.00 120.32 ? 655  SER D OG  1 
ATOM   12866 N N   . GLN D 1 581 ? -76.405 -0.094  0.801   1.00 104.25 ? 656  GLN D N   1 
ATOM   12867 C CA  . GLN D 1 581 ? -77.156 0.730   -0.135  1.00 107.14 ? 656  GLN D CA  1 
ATOM   12868 C C   . GLN D 1 581 ? -76.499 2.094   -0.281  1.00 104.05 ? 656  GLN D C   1 
ATOM   12869 O O   . GLN D 1 581 ? -76.125 2.500   -1.390  1.00 109.04 ? 656  GLN D O   1 
ATOM   12870 C CB  . GLN D 1 581 ? -78.607 0.854   0.336   1.00 106.81 ? 656  GLN D CB  1 
ATOM   12871 C CG  . GLN D 1 581 ? -79.550 1.462   -0.684  1.00 109.90 ? 656  GLN D CG  1 
ATOM   12872 C CD  . GLN D 1 581 ? -80.964 1.595   -0.153  1.00 121.35 ? 656  GLN D CD  1 
ATOM   12873 O OE1 . GLN D 1 581 ? -81.269 1.152   0.956   1.00 119.86 ? 656  GLN D OE1 1 
ATOM   12874 N NE2 . GLN D 1 581 ? -81.840 2.192   -0.951  1.00 133.07 ? 656  GLN D NE2 1 
ATOM   12875 N N   . LEU D 1 582 ? -76.273 2.778   0.847   1.00 96.74  ? 657  LEU D N   1 
ATOM   12876 C CA  . LEU D 1 582 ? -75.623 4.082   0.796   1.00 99.20  ? 657  LEU D CA  1 
ATOM   12877 C C   . LEU D 1 582 ? -74.316 3.986   0.029   1.00 107.69 ? 657  LEU D C   1 
ATOM   12878 O O   . LEU D 1 582 ? -74.104 4.712   -0.953  1.00 115.28 ? 657  LEU D O   1 
ATOM   12879 C CB  . LEU D 1 582 ? -75.383 4.613   2.210   1.00 101.61 ? 657  LEU D CB  1 
ATOM   12880 C CG  . LEU D 1 582 ? -74.675 5.966   2.315   1.00 93.36  ? 657  LEU D CG  1 
ATOM   12881 C CD1 . LEU D 1 582 ? -75.569 7.065   1.768   1.00 97.31  ? 657  LEU D CD1 1 
ATOM   12882 C CD2 . LEU D 1 582 ? -74.281 6.259   3.755   1.00 69.65  ? 657  LEU D CD2 1 
ATOM   12883 N N   . ILE D 1 583 ? -73.461 3.035   0.422   1.00 109.19 ? 658  ILE D N   1 
ATOM   12884 C CA  . ILE D 1 583 ? -72.179 2.870   -0.254  1.00 107.07 ? 658  ILE D CA  1 
ATOM   12885 C C   . ILE D 1 583 ? -72.404 2.761   -1.751  1.00 113.51 ? 658  ILE D C   1 
ATOM   12886 O O   . ILE D 1 583 ? -71.839 3.534   -2.538  1.00 115.95 ? 658  ILE D O   1 
ATOM   12887 C CB  . ILE D 1 583 ? -71.427 1.649   0.299   1.00 104.16 ? 658  ILE D CB  1 
ATOM   12888 C CG1 . ILE D 1 583 ? -71.307 1.754   1.818   1.00 109.78 ? 658  ILE D CG1 1 
ATOM   12889 C CG2 . ILE D 1 583 ? -70.044 1.560   -0.320  1.00 95.11  ? 658  ILE D CG2 1 
ATOM   12890 C CD1 . ILE D 1 583 ? -71.174 0.422   2.504   1.00 124.18 ? 658  ILE D CD1 1 
ATOM   12891 N N   . ASP D 1 584 ? -73.305 1.856   -2.154  1.00 110.70 ? 659  ASP D N   1 
ATOM   12892 C CA  . ASP D 1 584 ? -73.618 1.689   -3.568  1.00 106.82 ? 659  ASP D CA  1 
ATOM   12893 C C   . ASP D 1 584 ? -73.847 3.043   -4.219  1.00 109.03 ? 659  ASP D C   1 
ATOM   12894 O O   . ASP D 1 584 ? -73.092 3.452   -5.111  1.00 123.30 ? 659  ASP D O   1 
ATOM   12895 C CB  . ASP D 1 584 ? -74.841 0.788   -3.742  1.00 102.91 ? 659  ASP D CB  1 
ATOM   12896 C CG  . ASP D 1 584 ? -74.530 -0.668  -3.486  1.00 107.58 ? 659  ASP D CG  1 
ATOM   12897 O OD1 . ASP D 1 584 ? -73.622 -1.205  -4.154  1.00 112.08 ? 659  ASP D OD1 1 
ATOM   12898 O OD2 . ASP D 1 584 ? -75.198 -1.277  -2.625  1.00 106.94 ? 659  ASP D OD2 1 
ATOM   12899 N N   . GLU D 1 585 ? -74.835 3.788   -3.709  1.00 100.26 ? 660  GLU D N   1 
ATOM   12900 C CA  . GLU D 1 585 ? -75.124 5.111   -4.248  1.00 109.76 ? 660  GLU D CA  1 
ATOM   12901 C C   . GLU D 1 585 ? -73.841 5.913   -4.384  1.00 114.56 ? 660  GLU D C   1 
ATOM   12902 O O   . GLU D 1 585 ? -73.431 6.269   -5.497  1.00 120.28 ? 660  GLU D O   1 
ATOM   12903 C CB  . GLU D 1 585 ? -76.132 5.841   -3.357  1.00 111.89 ? 660  GLU D CB  1 
ATOM   12904 C CG  . GLU D 1 585 ? -77.497 5.180   -3.304  1.00 115.58 ? 660  GLU D CG  1 
ATOM   12905 C CD  . GLU D 1 585 ? -78.311 5.606   -2.097  1.00 127.43 ? 660  GLU D CD  1 
ATOM   12906 O OE1 . GLU D 1 585 ? -77.865 6.512   -1.361  1.00 128.75 ? 660  GLU D OE1 1 
ATOM   12907 O OE2 . GLU D 1 585 ? -79.394 5.026   -1.878  1.00 132.35 ? 660  GLU D OE2 1 
ATOM   12908 N N   . LEU D 1 586 ? -73.149 6.121   -3.258  1.00 120.13 ? 661  LEU D N   1 
ATOM   12909 C CA  . LEU D 1 586 ? -71.905 6.879   -3.276  1.00 117.89 ? 661  LEU D CA  1 
ATOM   12910 C C   . LEU D 1 586 ? -70.985 6.369   -4.374  1.00 118.38 ? 661  LEU D C   1 
ATOM   12911 O O   . LEU D 1 586 ? -70.626 7.118   -5.293  1.00 126.15 ? 661  LEU D O   1 
ATOM   12912 C CB  . LEU D 1 586 ? -71.220 6.804   -1.911  1.00 104.75 ? 661  LEU D CB  1 
ATOM   12913 C CG  . LEU D 1 586 ? -71.918 7.567   -0.785  1.00 91.72  ? 661  LEU D CG  1 
ATOM   12914 C CD1 . LEU D 1 586 ? -71.108 7.477   0.495   1.00 100.42 ? 661  LEU D CD1 1 
ATOM   12915 C CD2 . LEU D 1 586 ? -72.162 9.019   -1.173  1.00 89.02  ? 661  LEU D CD2 1 
ATOM   12916 N N   . ALA D 1 587 ? -70.672 5.067   -4.339  1.00 111.92 ? 662  ALA D N   1 
ATOM   12917 C CA  . ALA D 1 587 ? -69.766 4.493   -5.328  1.00 109.51 ? 662  ALA D CA  1 
ATOM   12918 C C   . ALA D 1 587 ? -70.199 4.875   -6.730  1.00 123.60 ? 662  ALA D C   1 
ATOM   12919 O O   . ALA D 1 587 ? -69.423 5.464   -7.495  1.00 114.27 ? 662  ALA D O   1 
ATOM   12920 C CB  . ALA D 1 587 ? -69.708 2.973   -5.181  1.00 92.18  ? 662  ALA D CB  1 
ATOM   12921 N N   . ASP D 1 588 ? -71.469 4.612   -7.054  1.00 127.14 ? 663  ASP D N   1 
ATOM   12922 C CA  . ASP D 1 588 ? -71.971 4.927   -8.383  1.00 120.78 ? 663  ASP D CA  1 
ATOM   12923 C C   . ASP D 1 588 ? -71.651 6.370   -8.734  1.00 122.23 ? 663  ASP D C   1 
ATOM   12924 O O   . ASP D 1 588 ? -70.921 6.641   -9.697  1.00 124.42 ? 663  ASP D O   1 
ATOM   12925 C CB  . ASP D 1 588 ? -73.474 4.654   -8.456  1.00 122.99 ? 663  ASP D CB  1 
ATOM   12926 C CG  . ASP D 1 588 ? -73.803 3.195   -8.217  1.00 121.90 ? 663  ASP D CG  1 
ATOM   12927 O OD1 . ASP D 1 588 ? -72.855 2.392   -8.090  1.00 115.33 ? 663  ASP D OD1 1 
ATOM   12928 O OD2 . ASP D 1 588 ? -75.003 2.849   -8.173  1.00 117.11 ? 663  ASP D OD2 1 
ATOM   12929 N N   . LYS D 1 589 ? -72.113 7.303   -7.894  1.00 124.85 ? 664  LYS D N   1 
ATOM   12930 C CA  . LYS D 1 589 ? -71.844 8.715   -8.138  1.00 132.78 ? 664  LYS D CA  1 
ATOM   12931 C C   . LYS D 1 589 ? -70.365 8.930   -8.409  1.00 131.04 ? 664  LYS D C   1 
ATOM   12932 O O   . LYS D 1 589 ? -69.982 9.450   -9.466  1.00 134.65 ? 664  LYS D O   1 
ATOM   12933 C CB  . LYS D 1 589 ? -72.302 9.560   -6.946  1.00 129.15 ? 664  LYS D CB  1 
ATOM   12934 C CG  . LYS D 1 589 ? -73.770 9.388   -6.573  1.00 143.90 ? 664  LYS D CG  1 
ATOM   12935 C CD  . LYS D 1 589 ? -74.671 9.398   -7.800  1.00 154.51 ? 664  LYS D CD  1 
ATOM   12936 C CE  . LYS D 1 589 ? -75.940 8.592   -7.552  1.00 151.36 ? 664  LYS D CE  1 
ATOM   12937 N NZ  . LYS D 1 589 ? -75.656 7.156   -7.276  1.00 149.83 ? 664  LYS D NZ  1 
ATOM   12938 N N   . PHE D 1 590 ? -69.516 8.446   -7.494  1.00 128.06 ? 665  PHE D N   1 
ATOM   12939 C CA  . PHE D 1 590 ? -68.079 8.640   -7.634  1.00 133.28 ? 665  PHE D CA  1 
ATOM   12940 C C   . PHE D 1 590 ? -67.624 8.191   -9.012  1.00 139.61 ? 665  PHE D C   1 
ATOM   12941 O O   . PHE D 1 590 ? -67.061 8.982   -9.782  1.00 144.92 ? 665  PHE D O   1 
ATOM   12942 C CB  . PHE D 1 590 ? -67.341 7.872   -6.538  1.00 132.12 ? 665  PHE D CB  1 
ATOM   12943 C CG  . PHE D 1 590 ? -65.914 8.300   -6.344  1.00 124.50 ? 665  PHE D CG  1 
ATOM   12944 C CD1 . PHE D 1 590 ? -65.617 9.612   -6.016  1.00 121.01 ? 665  PHE D CD1 1 
ATOM   12945 C CD2 . PHE D 1 590 ? -64.874 7.391   -6.458  1.00 112.10 ? 665  PHE D CD2 1 
ATOM   12946 C CE1 . PHE D 1 590 ? -64.314 10.017  -5.819  1.00 112.99 ? 665  PHE D CE1 1 
ATOM   12947 C CE2 . PHE D 1 590 ? -63.562 7.793   -6.263  1.00 104.88 ? 665  PHE D CE2 1 
ATOM   12948 C CZ  . PHE D 1 590 ? -63.285 9.108   -5.943  1.00 104.87 ? 665  PHE D CZ  1 
ATOM   12949 N N   . ASN D 1 591 ? -67.949 6.942   -9.370  1.00 138.56 ? 666  ASN D N   1 
ATOM   12950 C CA  . ASN D 1 591 ? -67.555 6.421   -10.673 1.00 132.07 ? 666  ASN D CA  1 
ATOM   12951 C C   . ASN D 1 591 ? -67.957 7.384   -11.775 1.00 138.59 ? 666  ASN D C   1 
ATOM   12952 O O   . ASN D 1 591 ? -67.106 7.853   -12.541 1.00 140.69 ? 666  ASN D O   1 
ATOM   12953 C CB  . ASN D 1 591 ? -68.173 5.041   -10.906 1.00 133.21 ? 666  ASN D CB  1 
ATOM   12954 C CG  . ASN D 1 591 ? -67.616 3.995   -9.966  1.00 135.16 ? 666  ASN D CG  1 
ATOM   12955 O OD1 . ASN D 1 591 ? -68.361 3.320   -9.255  1.00 137.83 ? 666  ASN D OD1 1 
ATOM   12956 N ND2 . ASN D 1 591 ? -66.295 3.870   -9.940  1.00 127.44 ? 666  ASN D ND2 1 
ATOM   12957 N N   . ARG D 1 592 ? -69.242 7.752   -11.815 1.00 142.60 ? 667  ARG D N   1 
ATOM   12958 C CA  . ARG D 1 592 ? -69.714 8.678   -12.838 1.00 146.05 ? 667  ARG D CA  1 
ATOM   12959 C C   . ARG D 1 592 ? -68.843 9.922   -12.862 1.00 141.55 ? 667  ARG D C   1 
ATOM   12960 O O   . ARG D 1 592 ? -68.231 10.249  -13.888 1.00 155.00 ? 667  ARG D O   1 
ATOM   12961 C CB  . ARG D 1 592 ? -71.176 9.043   -12.579 1.00 136.10 ? 667  ARG D CB  1 
ATOM   12962 C CG  . ARG D 1 592 ? -72.157 7.866   -12.601 1.00 136.43 ? 667  ARG D CG  1 
ATOM   12963 C CD  . ARG D 1 592 ? -72.043 6.961   -13.833 1.00 165.62 ? 667  ARG D CD  1 
ATOM   12964 N NE  . ARG D 1 592 ? -71.076 5.880   -13.674 1.00 177.66 ? 667  ARG D NE  1 
ATOM   12965 C CZ  . ARG D 1 592 ? -70.035 5.686   -14.472 1.00 189.81 ? 667  ARG D CZ  1 
ATOM   12966 N NH1 . ARG D 1 592 ? -69.827 6.447   -15.533 1.00 190.00 ? 667  ARG D NH1 1 
ATOM   12967 N NH2 . ARG D 1 592 ? -69.188 4.694   -14.206 1.00 190.27 ? 667  ARG D NH2 1 
ATOM   12968 N N   . LEU D 1 593 ? -68.715 10.582  -11.706 1.00 122.45 ? 668  LEU D N   1 
ATOM   12969 C CA  . LEU D 1 593 ? -67.904 11.789  -11.620 1.00 119.59 ? 668  LEU D CA  1 
ATOM   12970 C C   . LEU D 1 593 ? -66.506 11.529  -12.158 1.00 130.58 ? 668  LEU D C   1 
ATOM   12971 O O   . LEU D 1 593 ? -66.003 12.275  -13.008 1.00 138.65 ? 668  LEU D O   1 
ATOM   12972 C CB  . LEU D 1 593 ? -67.852 12.271  -10.170 1.00 126.19 ? 668  LEU D CB  1 
ATOM   12973 C CG  . LEU D 1 593 ? -69.136 12.919  -9.647  1.00 114.03 ? 668  LEU D CG  1 
ATOM   12974 C CD1 . LEU D 1 593 ? -68.956 13.443  -8.230  1.00 113.60 ? 668  LEU D CD1 1 
ATOM   12975 C CD2 . LEU D 1 593 ? -69.601 14.026  -10.577 1.00 122.62 ? 668  LEU D CD2 1 
ATOM   12976 N N   . LEU D 1 594 ? -65.890 10.427  -11.716 1.00 141.61 ? 669  LEU D N   1 
ATOM   12977 C CA  . LEU D 1 594 ? -64.532 10.119  -12.150 1.00 144.27 ? 669  LEU D CA  1 
ATOM   12978 C C   . LEU D 1 594 ? -64.456 9.999   -13.666 1.00 145.88 ? 669  LEU D C   1 
ATOM   12979 O O   . LEU D 1 594 ? -63.543 10.553  -14.290 1.00 148.31 ? 669  LEU D O   1 
ATOM   12980 C CB  . LEU D 1 594 ? -64.033 8.842   -11.468 1.00 129.44 ? 669  LEU D CB  1 
ATOM   12981 C CG  . LEU D 1 594 ? -63.318 9.005   -10.118 1.00 109.60 ? 669  LEU D CG  1 
ATOM   12982 C CD1 . LEU D 1 594 ? -61.897 9.487   -10.338 1.00 103.73 ? 669  LEU D CD1 1 
ATOM   12983 C CD2 . LEU D 1 594 ? -64.055 9.944   -9.176  1.00 121.83 ? 669  LEU D CD2 1 
ATOM   12984 N N   . GLU D 1 595 ? -65.440 9.331   -14.283 1.00 144.92 ? 670  GLU D N   1 
ATOM   12985 C CA  . GLU D 1 595 ? -65.418 9.178   -15.736 1.00 146.46 ? 670  GLU D CA  1 
ATOM   12986 C C   . GLU D 1 595 ? -65.381 10.534  -16.425 1.00 145.10 ? 670  GLU D C   1 
ATOM   12987 O O   . GLU D 1 595 ? -64.715 10.699  -17.454 1.00 147.07 ? 670  GLU D O   1 
ATOM   12988 C CB  . GLU D 1 595 ? -66.628 8.368   -16.199 1.00 152.55 ? 670  GLU D CB  1 
ATOM   12989 C CG  . GLU D 1 595 ? -66.708 6.979   -15.587 1.00 163.49 ? 670  GLU D CG  1 
ATOM   12990 C CD  . GLU D 1 595 ? -65.882 5.945   -16.327 1.00 163.46 ? 670  GLU D CD  1 
ATOM   12991 O OE1 . GLU D 1 595 ? -66.479 5.059   -16.972 1.00 156.57 ? 670  GLU D OE1 1 
ATOM   12992 O OE2 . GLU D 1 595 ? -64.636 6.013   -16.254 1.00 159.51 ? 670  GLU D OE2 1 
ATOM   12993 N N   . ASP D 1 596 ? -66.074 11.523  -15.861 1.00 149.15 ? 671  ASP D N   1 
ATOM   12994 C CA  . ASP D 1 596 ? -66.001 12.861  -16.427 1.00 150.17 ? 671  ASP D CA  1 
ATOM   12995 C C   . ASP D 1 596 ? -64.772 13.606  -15.922 1.00 156.21 ? 671  ASP D C   1 
ATOM   12996 O O   . ASP D 1 596 ? -64.173 14.394  -16.662 1.00 176.33 ? 671  ASP D O   1 
ATOM   12997 C CB  . ASP D 1 596 ? -67.273 13.641  -16.102 1.00 147.17 ? 671  ASP D CB  1 
ATOM   12998 C CG  . ASP D 1 596 ? -67.238 15.049  -16.645 1.00 169.57 ? 671  ASP D CG  1 
ATOM   12999 O OD1 . ASP D 1 596 ? -67.131 15.201  -17.879 1.00 188.75 ? 671  ASP D OD1 1 
ATOM   13000 O OD2 . ASP D 1 596 ? -67.309 16.001  -15.840 1.00 173.77 ? 671  ASP D OD2 1 
ATOM   13001 N N   . PHE D 1 597 ? -64.374 13.354  -14.673 1.00 144.60 ? 672  PHE D N   1 
ATOM   13002 C CA  . PHE D 1 597 ? -63.268 14.103  -14.086 1.00 145.31 ? 672  PHE D CA  1 
ATOM   13003 C C   . PHE D 1 597 ? -61.948 13.755  -14.761 1.00 148.24 ? 672  PHE D C   1 
ATOM   13004 O O   . PHE D 1 597 ? -61.119 14.638  -15.013 1.00 141.14 ? 672  PHE D O   1 
ATOM   13005 C CB  . PHE D 1 597 ? -63.194 13.825  -12.585 1.00 144.51 ? 672  PHE D CB  1 
ATOM   13006 C CG  . PHE D 1 597 ? -62.323 14.784  -11.829 1.00 139.06 ? 672  PHE D CG  1 
ATOM   13007 C CD1 . PHE D 1 597 ? -62.615 16.138  -11.811 1.00 135.84 ? 672  PHE D CD1 1 
ATOM   13008 C CD2 . PHE D 1 597 ? -61.213 14.333  -11.134 1.00 128.57 ? 672  PHE D CD2 1 
ATOM   13009 C CE1 . PHE D 1 597 ? -61.817 17.023  -11.114 1.00 129.90 ? 672  PHE D CE1 1 
ATOM   13010 C CE2 . PHE D 1 597 ? -60.410 15.214  -10.436 1.00 121.73 ? 672  PHE D CE2 1 
ATOM   13011 C CZ  . PHE D 1 597 ? -60.713 16.562  -10.427 1.00 127.97 ? 672  PHE D CZ  1 
ATOM   13012 N N   . LEU D 1 598 ? -61.741 12.478  -15.068 1.00 148.58 ? 673  LEU D N   1 
ATOM   13013 C CA  . LEU D 1 598 ? -60.507 12.007  -15.678 1.00 153.95 ? 673  LEU D CA  1 
ATOM   13014 C C   . LEU D 1 598 ? -60.532 12.075  -17.198 1.00 164.55 ? 673  LEU D C   1 
ATOM   13015 O O   . LEU D 1 598 ? -59.544 11.696  -17.836 1.00 166.32 ? 673  LEU D O   1 
ATOM   13016 C CB  . LEU D 1 598 ? -60.220 10.573  -15.226 1.00 146.48 ? 673  LEU D CB  1 
ATOM   13017 C CG  . LEU D 1 598 ? -60.042 10.411  -13.715 1.00 136.62 ? 673  LEU D CG  1 
ATOM   13018 C CD1 . LEU D 1 598 ? -59.553 9.015   -13.375 1.00 138.71 ? 673  LEU D CD1 1 
ATOM   13019 C CD2 . LEU D 1 598 ? -59.097 11.469  -13.163 1.00 130.70 ? 673  LEU D CD2 1 
ATOM   13020 N N   . GLN D 1 599 ? -61.630 12.539  -17.792 1.00 175.48 ? 674  GLN D N   1 
ATOM   13021 C CA  . GLN D 1 599 ? -61.682 12.721  -19.237 1.00 179.53 ? 674  GLN D CA  1 
ATOM   13022 C C   . GLN D 1 599 ? -60.686 13.792  -19.662 1.00 183.19 ? 674  GLN D C   1 
ATOM   13023 O O   . GLN D 1 599 ? -60.631 14.874  -19.072 1.00 209.00 ? 674  GLN D O   1 
ATOM   13024 C CB  . GLN D 1 599 ? -63.097 13.105  -19.669 1.00 177.79 ? 674  GLN D CB  1 
ATOM   13025 C CG  . GLN D 1 599 ? -63.226 13.514  -21.131 1.00 179.44 ? 674  GLN D CG  1 
ATOM   13026 C CD  . GLN D 1 599 ? -62.613 12.504  -22.083 1.00 182.77 ? 674  GLN D CD  1 
ATOM   13027 O OE1 . GLN D 1 599 ? -61.651 12.802  -22.792 1.00 184.42 ? 674  GLN D OE1 1 
ATOM   13028 N NE2 . GLN D 1 599 ? -63.171 11.299  -22.105 1.00 176.48 ? 674  GLN D NE2 1 
ATOM   13029 N N   . GLU D 1 600 ? -59.893 13.482  -20.691 1.00 179.84 ? 675  GLU D N   1 
ATOM   13030 C CA  . GLU D 1 600 ? -58.848 14.406  -21.124 1.00 176.77 ? 675  GLU D CA  1 
ATOM   13031 C C   . GLU D 1 600 ? -59.441 15.703  -21.660 1.00 179.52 ? 675  GLU D C   1 
ATOM   13032 O O   . GLU D 1 600 ? -58.922 16.792  -21.386 1.00 175.59 ? 675  GLU D O   1 
ATOM   13033 C CB  . GLU D 1 600 ? -57.959 13.750  -22.183 1.00 160.65 ? 675  GLU D CB  1 
ATOM   13034 C CG  . GLU D 1 600 ? -57.385 12.392  -21.792 1.00 167.68 ? 675  GLU D CG  1 
ATOM   13035 C CD  . GLU D 1 600 ? -58.366 11.255  -22.001 1.00 169.93 ? 675  GLU D CD  1 
ATOM   13036 O OE1 . GLU D 1 600 ? -58.827 11.072  -23.147 1.00 173.25 ? 675  GLU D OE1 1 
ATOM   13037 O OE2 . GLU D 1 600 ? -58.676 10.545  -21.021 1.00 165.73 ? 675  GLU D OE2 1 
ATOM   13038 N N   . GLY D 1 601 ? -60.529 15.610  -22.426 1.00 184.62 ? 676  GLY D N   1 
ATOM   13039 C CA  . GLY D 1 601 ? -61.133 16.811  -22.977 1.00 188.08 ? 676  GLY D CA  1 
ATOM   13040 C C   . GLY D 1 601 ? -61.820 17.660  -21.924 1.00 194.55 ? 676  GLY D C   1 
ATOM   13041 O O   . GLY D 1 601 ? -61.796 18.892  -21.995 1.00 195.65 ? 676  GLY D O   1 
ATOM   13042 N N   . GLU D 1 602 ? -62.441 17.017  -20.937 1.00 198.22 ? 677  GLU D N   1 
ATOM   13043 C CA  . GLU D 1 602 ? -63.141 17.746  -19.888 1.00 201.81 ? 677  GLU D CA  1 
ATOM   13044 C C   . GLU D 1 602 ? -62.160 18.557  -19.051 1.00 198.95 ? 677  GLU D C   1 
ATOM   13045 O O   . GLU D 1 602 ? -61.154 18.032  -18.564 1.00 191.44 ? 677  GLU D O   1 
ATOM   13046 C CB  . GLU D 1 602 ? -63.919 16.774  -19.000 1.00 207.60 ? 677  GLU D CB  1 
ATOM   13047 C CG  . GLU D 1 602 ? -64.508 17.403  -17.745 1.00 226.25 ? 677  GLU D CG  1 
ATOM   13048 C CD  . GLU D 1 602 ? -65.526 18.485  -18.050 1.00 240.28 ? 677  GLU D CD  1 
ATOM   13049 O OE1 . GLU D 1 602 ? -66.564 18.170  -18.669 1.00 240.35 ? 677  GLU D OE1 1 
ATOM   13050 O OE2 . GLU D 1 602 ? -65.292 19.650  -17.665 1.00 276.47 ? 677  GLU D OE2 1 
ATOM   13051 N N   . GLU D 1 603 ? -62.458 19.844  -18.885 1.00 199.16 ? 678  GLU D N   1 
ATOM   13052 C CA  . GLU D 1 603 ? -61.631 20.722  -18.074 1.00 190.01 ? 678  GLU D CA  1 
ATOM   13053 C C   . GLU D 1 603 ? -62.333 20.964  -16.748 1.00 186.32 ? 678  GLU D C   1 
ATOM   13054 O O   . GLU D 1 603 ? -63.367 21.650  -16.723 1.00 195.44 ? 678  GLU D O   1 
ATOM   13055 C CB  . GLU D 1 603 ? -61.378 22.043  -18.796 1.00 185.44 ? 678  GLU D CB  1 
ATOM   13056 C CG  . GLU D 1 603 ? -61.032 21.898  -20.278 1.00 178.61 ? 678  GLU D CG  1 
ATOM   13057 C CD  . GLU D 1 603 ? -59.661 21.289  -20.524 1.00 185.97 ? 678  GLU D CD  1 
ATOM   13058 O OE1 . GLU D 1 603 ? -59.457 20.098  -20.202 1.00 187.20 ? 678  GLU D OE1 1 
ATOM   13059 O OE2 . GLU D 1 603 ? -58.783 22.009  -21.043 1.00 182.83 ? 678  GLU D OE2 1 
ATOM   13060 N N   . PRO D 1 604 ? -61.825 20.437  -15.635 1.00 175.68 ? 679  PRO D N   1 
ATOM   13061 C CA  . PRO D 1 604 ? -62.588 20.482  -14.379 1.00 171.15 ? 679  PRO D CA  1 
ATOM   13062 C C   . PRO D 1 604 ? -62.712 21.901  -13.843 1.00 160.50 ? 679  PRO D C   1 
ATOM   13063 O O   . PRO D 1 604 ? -61.728 22.639  -13.759 1.00 157.41 ? 679  PRO D O   1 
ATOM   13064 C CB  . PRO D 1 604 ? -61.765 19.596  -13.436 1.00 171.06 ? 679  PRO D CB  1 
ATOM   13065 C CG  . PRO D 1 604 ? -60.378 19.661  -13.988 1.00 167.48 ? 679  PRO D CG  1 
ATOM   13066 C CD  . PRO D 1 604 ? -60.548 19.720  -15.479 1.00 166.53 ? 679  PRO D CD  1 
ATOM   13067 N N   . ASP D 1 605 ? -63.934 22.272  -13.476 1.00 159.80 ? 680  ASP D N   1 
ATOM   13068 C CA  . ASP D 1 605 ? -64.206 23.555  -12.850 1.00 157.31 ? 680  ASP D CA  1 
ATOM   13069 C C   . ASP D 1 605 ? -64.158 23.428  -11.328 1.00 152.81 ? 680  ASP D C   1 
ATOM   13070 O O   . ASP D 1 605 ? -63.987 22.340  -10.774 1.00 147.93 ? 680  ASP D O   1 
ATOM   13071 C CB  . ASP D 1 605 ? -65.562 24.096  -13.313 1.00 144.27 ? 680  ASP D CB  1 
ATOM   13072 C CG  . ASP D 1 605 ? -66.689 23.091  -13.140 1.00 144.18 ? 680  ASP D CG  1 
ATOM   13073 O OD1 . ASP D 1 605 ? -67.344 22.758  -14.150 1.00 142.37 ? 680  ASP D OD1 1 
ATOM   13074 O OD2 . ASP D 1 605 ? -66.927 22.636  -12.002 1.00 150.52 ? 680  ASP D OD2 1 
ATOM   13075 N N   . GLU D 1 606 ? -64.300 24.573  -10.652 1.00 151.40 ? 681  GLU D N   1 
ATOM   13076 C CA  . GLU D 1 606 ? -64.346 24.588  -9.193  1.00 147.64 ? 681  GLU D CA  1 
ATOM   13077 C C   . GLU D 1 606 ? -65.393 23.612  -8.671  1.00 146.63 ? 681  GLU D C   1 
ATOM   13078 O O   . GLU D 1 606 ? -65.131 22.815  -7.761  1.00 169.02 ? 681  GLU D O   1 
ATOM   13079 C CB  . GLU D 1 606 ? -64.652 26.005  -8.694  1.00 153.48 ? 681  GLU D CB  1 
ATOM   13080 C CG  . GLU D 1 606 ? -63.881 27.127  -9.385  1.00 154.20 ? 681  GLU D CG  1 
ATOM   13081 C CD  . GLU D 1 606 ? -62.432 27.214  -8.948  1.00 151.88 ? 681  GLU D CD  1 
ATOM   13082 O OE1 . GLU D 1 606 ? -62.051 26.509  -7.991  1.00 151.24 ? 681  GLU D OE1 1 
ATOM   13083 O OE2 . GLU D 1 606 ? -61.674 28.001  -9.555  1.00 148.66 ? 681  GLU D OE2 1 
ATOM   13084 N N   . ASP D 1 607 ? -66.591 23.656  -9.259  1.00 140.56 ? 682  ASP D N   1 
ATOM   13085 C CA  . ASP D 1 607 ? -67.685 22.806  -8.804  1.00 138.49 ? 682  ASP D CA  1 
ATOM   13086 C C   . ASP D 1 607 ? -67.390 21.331  -9.046  1.00 142.81 ? 682  ASP D C   1 
ATOM   13087 O O   . ASP D 1 607 ? -67.762 20.482  -8.231  1.00 153.33 ? 682  ASP D O   1 
ATOM   13088 C CB  . ASP D 1 607 ? -68.983 23.212  -9.499  1.00 134.51 ? 682  ASP D CB  1 
ATOM   13089 C CG  . ASP D 1 607 ? -70.113 22.243  -9.228  1.00 140.40 ? 682  ASP D CG  1 
ATOM   13090 O OD1 . ASP D 1 607 ? -70.513 22.106  -8.054  1.00 130.56 ? 682  ASP D OD1 1 
ATOM   13091 O OD2 . ASP D 1 607 ? -70.597 21.612  -10.192 1.00 145.82 ? 682  ASP D OD2 1 
ATOM   13092 N N   . ASP D 1 608 ? -66.737 21.003  -10.162 1.00 135.13 ? 683  ASP D N   1 
ATOM   13093 C CA  . ASP D 1 608 ? -66.389 19.610  -10.429 1.00 138.41 ? 683  ASP D CA  1 
ATOM   13094 C C   . ASP D 1 608 ? -65.448 19.069  -9.359  1.00 138.80 ? 683  ASP D C   1 
ATOM   13095 O O   . ASP D 1 608 ? -65.646 17.961  -8.837  1.00 135.77 ? 683  ASP D O   1 
ATOM   13096 C CB  . ASP D 1 608 ? -65.753 19.487  -11.815 1.00 150.00 ? 683  ASP D CB  1 
ATOM   13097 C CG  . ASP D 1 608 ? -66.778 19.495  -12.929 1.00 152.44 ? 683  ASP D CG  1 
ATOM   13098 O OD1 . ASP D 1 608 ? -67.984 19.618  -12.627 1.00 149.71 ? 683  ASP D OD1 1 
ATOM   13099 O OD2 . ASP D 1 608 ? -66.378 19.385  -14.107 1.00 148.60 ? 683  ASP D OD2 1 
ATOM   13100 N N   . ALA D 1 609 ? -64.407 19.840  -9.035  1.00 136.38 ? 684  ALA D N   1 
ATOM   13101 C CA  . ALA D 1 609 ? -63.484 19.452  -7.976  1.00 127.99 ? 684  ALA D CA  1 
ATOM   13102 C C   . ALA D 1 609 ? -64.215 19.297  -6.650  1.00 133.48 ? 684  ALA D C   1 
ATOM   13103 O O   . ALA D 1 609 ? -63.988 18.331  -5.914  1.00 136.00 ? 684  ALA D O   1 
ATOM   13104 C CB  . ALA D 1 609 ? -62.359 20.480  -7.858  1.00 113.68 ? 684  ALA D CB  1 
ATOM   13105 N N   . TYR D 1 610 ? -65.109 20.239  -6.336  1.00 134.72 ? 685  TYR D N   1 
ATOM   13106 C CA  . TYR D 1 610 ? -65.882 20.145  -5.100  1.00 126.37 ? 685  TYR D CA  1 
ATOM   13107 C C   . TYR D 1 610 ? -66.713 18.866  -5.057  1.00 128.73 ? 685  TYR D C   1 
ATOM   13108 O O   . TYR D 1 610 ? -66.770 18.188  -4.025  1.00 127.64 ? 685  TYR D O   1 
ATOM   13109 C CB  . TYR D 1 610 ? -66.776 21.376  -4.952  1.00 126.99 ? 685  TYR D CB  1 
ATOM   13110 C CG  . TYR D 1 610 ? -67.536 21.443  -3.646  1.00 138.70 ? 685  TYR D CG  1 
ATOM   13111 C CD1 . TYR D 1 610 ? -66.868 21.450  -2.427  1.00 138.45 ? 685  TYR D CD1 1 
ATOM   13112 C CD2 . TYR D 1 610 ? -68.923 21.507  -3.634  1.00 142.27 ? 685  TYR D CD2 1 
ATOM   13113 C CE1 . TYR D 1 610 ? -67.565 21.514  -1.232  1.00 140.65 ? 685  TYR D CE1 1 
ATOM   13114 C CE2 . TYR D 1 610 ? -69.627 21.572  -2.448  1.00 137.30 ? 685  TYR D CE2 1 
ATOM   13115 C CZ  . TYR D 1 610 ? -68.944 21.575  -1.249  1.00 138.32 ? 685  TYR D CZ  1 
ATOM   13116 O OH  . TYR D 1 610 ? -69.648 21.640  -0.068  1.00 133.37 ? 685  TYR D OH  1 
ATOM   13117 N N   . GLN D 1 611 ? -67.350 18.513  -6.176  1.00 127.47 ? 686  GLN D N   1 
ATOM   13118 C CA  . GLN D 1 611 ? -68.208 17.331  -6.210  1.00 115.93 ? 686  GLN D CA  1 
ATOM   13119 C C   . GLN D 1 611 ? -67.401 16.057  -5.992  1.00 115.80 ? 686  GLN D C   1 
ATOM   13120 O O   . GLN D 1 611 ? -67.749 15.221  -5.138  1.00 118.74 ? 686  GLN D O   1 
ATOM   13121 C CB  . GLN D 1 611 ? -68.953 17.264  -7.546  1.00 120.46 ? 686  GLN D CB  1 
ATOM   13122 C CG  . GLN D 1 611 ? -69.960 18.380  -7.779  1.00 136.28 ? 686  GLN D CG  1 
ATOM   13123 C CD  . GLN D 1 611 ? -70.736 18.748  -6.534  1.00 133.79 ? 686  GLN D CD  1 
ATOM   13124 O OE1 . GLN D 1 611 ? -71.475 17.931  -5.985  1.00 130.42 ? 686  GLN D OE1 1 
ATOM   13125 N NE2 . GLN D 1 611 ? -70.574 19.986  -6.081  1.00 129.30 ? 686  GLN D NE2 1 
ATOM   13126 N N   . VAL D 1 612 ? -66.324 15.884  -6.769  1.00 116.25 ? 687  VAL D N   1 
ATOM   13127 C CA  . VAL D 1 612 ? -65.533 14.661  -6.639  1.00 117.73 ? 687  VAL D CA  1 
ATOM   13128 C C   . VAL D 1 612 ? -64.912 14.592  -5.252  1.00 121.20 ? 687  VAL D C   1 
ATOM   13129 O O   . VAL D 1 612 ? -64.846 13.519  -4.639  1.00 117.63 ? 687  VAL D O   1 
ATOM   13130 C CB  . VAL D 1 612 ? -64.461 14.560  -7.743  1.00 113.63 ? 687  VAL D CB  1 
ATOM   13131 C CG1 . VAL D 1 612 ? -63.697 15.857  -7.892  1.00 122.33 ? 687  VAL D CG1 1 
ATOM   13132 C CG2 . VAL D 1 612 ? -63.508 13.398  -7.470  1.00 107.56 ? 687  VAL D CG2 1 
ATOM   13133 N N   . LEU D 1 613 ? -64.487 15.741  -4.717  1.00 123.11 ? 688  LEU D N   1 
ATOM   13134 C CA  . LEU D 1 613 ? -63.899 15.767  -3.384  1.00 117.09 ? 688  LEU D CA  1 
ATOM   13135 C C   . LEU D 1 613 ? -64.912 15.368  -2.322  1.00 110.51 ? 688  LEU D C   1 
ATOM   13136 O O   . LEU D 1 613 ? -64.584 14.615  -1.404  1.00 108.14 ? 688  LEU D O   1 
ATOM   13137 C CB  . LEU D 1 613 ? -63.333 17.156  -3.088  1.00 115.16 ? 688  LEU D CB  1 
ATOM   13138 C CG  . LEU D 1 613 ? -62.784 17.361  -1.675  1.00 108.62 ? 688  LEU D CG  1 
ATOM   13139 C CD1 . LEU D 1 613 ? -61.629 16.409  -1.394  1.00 111.54 ? 688  LEU D CD1 1 
ATOM   13140 C CD2 . LEU D 1 613 ? -62.358 18.806  -1.470  1.00 110.24 ? 688  LEU D CD2 1 
ATOM   13141 N N   . SER D 1 614 ? -66.148 15.859  -2.428  1.00 106.49 ? 689  SER D N   1 
ATOM   13142 C CA  . SER D 1 614 ? -67.163 15.529  -1.431  1.00 103.89 ? 689  SER D CA  1 
ATOM   13143 C C   . SER D 1 614 ? -67.479 14.039  -1.444  1.00 101.99 ? 689  SER D C   1 
ATOM   13144 O O   . SER D 1 614 ? -67.514 13.383  -0.390  1.00 111.29 ? 689  SER D O   1 
ATOM   13145 C CB  . SER D 1 614 ? -68.427 16.351  -1.684  1.00 105.28 ? 689  SER D CB  1 
ATOM   13146 O OG  . SER D 1 614 ? -68.125 17.732  -1.784  1.00 116.13 ? 689  SER D OG  1 
ATOM   13147 N N   . THR D 1 615 ? -67.718 13.483  -2.637  1.00 100.50 ? 690  THR D N   1 
ATOM   13148 C CA  . THR D 1 615 ? -68.009 12.053  -2.716  1.00 113.31 ? 690  THR D CA  1 
ATOM   13149 C C   . THR D 1 615 ? -66.823 11.222  -2.228  1.00 103.02 ? 690  THR D C   1 
ATOM   13150 O O   . THR D 1 615 ? -67.003 10.209  -1.536  1.00 96.43  ? 690  THR D O   1 
ATOM   13151 C CB  . THR D 1 615 ? -68.399 11.666  -4.143  1.00 113.32 ? 690  THR D CB  1 
ATOM   13152 O OG1 . THR D 1 615 ? -67.415 12.155  -5.062  1.00 113.89 ? 690  THR D OG1 1 
ATOM   13153 C CG2 . THR D 1 615 ? -69.764 12.250  -4.501  1.00 113.71 ? 690  THR D CG2 1 
ATOM   13154 N N   . LEU D 1 616 ? -65.600 11.653  -2.557  1.00 103.10 ? 691  LEU D N   1 
ATOM   13155 C CA  . LEU D 1 616 ? -64.404 10.956  -2.099  1.00 104.57 ? 691  LEU D CA  1 
ATOM   13156 C C   . LEU D 1 616 ? -64.277 11.007  -0.582  1.00 99.27  ? 691  LEU D C   1 
ATOM   13157 O O   . LEU D 1 616 ? -63.881 10.022  0.047   1.00 95.44  ? 691  LEU D O   1 
ATOM   13158 C CB  . LEU D 1 616 ? -63.171 11.571  -2.761  1.00 93.36  ? 691  LEU D CB  1 
ATOM   13159 C CG  . LEU D 1 616 ? -61.795 11.111  -2.279  1.00 84.98  ? 691  LEU D CG  1 
ATOM   13160 C CD1 . LEU D 1 616 ? -61.599 9.628   -2.537  1.00 78.00  ? 691  LEU D CD1 1 
ATOM   13161 C CD2 . LEU D 1 616 ? -60.702 11.929  -2.944  1.00 85.67  ? 691  LEU D CD2 1 
ATOM   13162 N N   . LYS D 1 617 ? -64.595 12.155  0.020   1.00 99.36  ? 692  LYS D N   1 
ATOM   13163 C CA  . LYS D 1 617 ? -64.544 12.282  1.473   1.00 93.83  ? 692  LYS D CA  1 
ATOM   13164 C C   . LYS D 1 617 ? -65.528 11.333  2.140   1.00 86.17  ? 692  LYS D C   1 
ATOM   13165 O O   . LYS D 1 617 ? -65.185 10.655  3.117   1.00 86.55  ? 692  LYS D O   1 
ATOM   13166 C CB  . LYS D 1 617 ? -64.825 13.731  1.872   1.00 83.56  ? 692  LYS D CB  1 
ATOM   13167 C CG  . LYS D 1 617 ? -63.713 14.704  1.492   1.00 93.81  ? 692  LYS D CG  1 
ATOM   13168 C CD  . LYS D 1 617 ? -63.998 16.120  1.975   1.00 82.18  ? 692  LYS D CD  1 
ATOM   13169 C CE  . LYS D 1 617 ? -64.038 16.219  3.490   1.00 88.88  ? 692  LYS D CE  1 
ATOM   13170 N NZ  . LYS D 1 617 ? -64.268 17.627  3.924   1.00 90.11  ? 692  LYS D NZ  1 
ATOM   13171 N N   . ARG D 1 618 ? -66.754 11.262  1.618   1.00 84.56  ? 693  ARG D N   1 
ATOM   13172 C CA  . ARG D 1 618 ? -67.737 10.336  2.179   1.00 94.21  ? 693  ARG D CA  1 
ATOM   13173 C C   . ARG D 1 618 ? -67.255 8.889   2.076   1.00 90.80  ? 693  ARG D C   1 
ATOM   13174 O O   . ARG D 1 618 ? -67.282 8.132   3.062   1.00 84.28  ? 693  ARG D O   1 
ATOM   13175 C CB  . ARG D 1 618 ? -69.077 10.523  1.469   1.00 89.19  ? 693  ARG D CB  1 
ATOM   13176 C CG  . ARG D 1 618 ? -69.728 11.865  1.771   1.00 96.22  ? 693  ARG D CG  1 
ATOM   13177 C CD  . ARG D 1 618 ? -70.544 12.379  0.598   1.00 92.99  ? 693  ARG D CD  1 
ATOM   13178 N NE  . ARG D 1 618 ? -70.849 13.797  0.748   1.00 92.14  ? 693  ARG D NE  1 
ATOM   13179 C CZ  . ARG D 1 618 ? -71.543 14.512  -0.127  1.00 109.42 ? 693  ARG D CZ  1 
ATOM   13180 N NH1 . ARG D 1 618 ? -72.016 13.974  -1.239  1.00 123.29 ? 693  ARG D NH1 1 
ATOM   13181 N NH2 . ARG D 1 618 ? -71.757 15.802  0.115   1.00 105.71 ? 693  ARG D NH2 1 
ATOM   13182 N N   . ILE D 1 619 ? -66.789 8.494   0.886   1.00 88.64  ? 694  ILE D N   1 
ATOM   13183 C CA  . ILE D 1 619 ? -66.352 7.114   0.685   1.00 87.73  ? 694  ILE D CA  1 
ATOM   13184 C C   . ILE D 1 619 ? -65.153 6.791   1.569   1.00 87.07  ? 694  ILE D C   1 
ATOM   13185 O O   . ILE D 1 619 ? -65.055 5.692   2.121   1.00 81.60  ? 694  ILE D O   1 
ATOM   13186 C CB  . ILE D 1 619 ? -66.044 6.855   -0.800  1.00 97.62  ? 694  ILE D CB  1 
ATOM   13187 C CG1 . ILE D 1 619 ? -67.304 7.043   -1.644  1.00 105.81 ? 694  ILE D CG1 1 
ATOM   13188 C CG2 . ILE D 1 619 ? -65.473 5.459   -0.987  1.00 87.42  ? 694  ILE D CG2 1 
ATOM   13189 C CD1 . ILE D 1 619 ? -67.069 6.860   -3.121  1.00 121.19 ? 694  ILE D CD1 1 
ATOM   13190 N N   . THR D 1 620 ? -64.227 7.739   1.720   1.00 86.55  ? 695  THR D N   1 
ATOM   13191 C CA  . THR D 1 620 ? -63.045 7.516   2.547   1.00 84.69  ? 695  THR D CA  1 
ATOM   13192 C C   . THR D 1 620 ? -63.425 7.351   4.013   1.00 79.28  ? 695  THR D C   1 
ATOM   13193 O O   . THR D 1 620 ? -62.925 6.451   4.707   1.00 82.24  ? 695  THR D O   1 
ATOM   13194 C CB  . THR D 1 620 ? -62.072 8.685   2.374   1.00 91.46  ? 695  THR D CB  1 
ATOM   13195 O OG1 . THR D 1 620 ? -61.728 8.828   0.989   1.00 85.70  ? 695  THR D OG1 1 
ATOM   13196 C CG2 . THR D 1 620 ? -60.814 8.468   3.190   1.00 89.11  ? 695  THR D CG2 1 
ATOM   13197 N N   . ALA D 1 621 ? -64.302 8.231   4.504   1.00 66.16  ? 696  ALA D N   1 
ATOM   13198 C CA  . ALA D 1 621 ? -64.765 8.129   5.881   1.00 62.78  ? 696  ALA D CA  1 
ATOM   13199 C C   . ALA D 1 621 ? -65.396 6.771   6.150   1.00 69.34  ? 696  ALA D C   1 
ATOM   13200 O O   . ALA D 1 621 ? -65.121 6.145   7.179   1.00 65.85  ? 696  ALA D O   1 
ATOM   13201 C CB  . ALA D 1 621 ? -65.753 9.254   6.184   1.00 68.23  ? 696  ALA D CB  1 
ATOM   13202 N N   . PHE D 1 622 ? -66.232 6.283   5.229   1.00 76.24  ? 697  PHE D N   1 
ATOM   13203 C CA  . PHE D 1 622 ? -66.841 4.977   5.478   1.00 81.44  ? 697  PHE D CA  1 
ATOM   13204 C C   . PHE D 1 622 ? -65.862 3.831   5.254   1.00 80.60  ? 697  PHE D C   1 
ATOM   13205 O O   . PHE D 1 622 ? -65.990 2.784   5.897   1.00 82.95  ? 697  PHE D O   1 
ATOM   13206 C CB  . PHE D 1 622 ? -68.098 4.791   4.630   1.00 83.41  ? 697  PHE D CB  1 
ATOM   13207 C CG  . PHE D 1 622 ? -69.327 5.398   5.244   1.00 74.44  ? 697  PHE D CG  1 
ATOM   13208 C CD1 . PHE D 1 622 ? -69.440 6.770   5.387   1.00 78.64  ? 697  PHE D CD1 1 
ATOM   13209 C CD2 . PHE D 1 622 ? -70.356 4.593   5.707   1.00 74.07  ? 697  PHE D CD2 1 
ATOM   13210 C CE1 . PHE D 1 622 ? -70.565 7.330   5.962   1.00 85.45  ? 697  PHE D CE1 1 
ATOM   13211 C CE2 . PHE D 1 622 ? -71.486 5.148   6.285   1.00 74.21  ? 697  PHE D CE2 1 
ATOM   13212 C CZ  . PHE D 1 622 ? -71.589 6.519   6.412   1.00 73.48  ? 697  PHE D CZ  1 
ATOM   13213 N N   . HIS D 1 623 ? -64.874 4.009   4.376   1.00 81.45  ? 698  HIS D N   1 
ATOM   13214 C CA  . HIS D 1 623 ? -63.912 2.946   4.112   1.00 83.57  ? 698  HIS D CA  1 
ATOM   13215 C C   . HIS D 1 623 ? -62.965 2.749   5.285   1.00 86.10  ? 698  HIS D C   1 
ATOM   13216 O O   . HIS D 1 623 ? -62.431 1.650   5.472   1.00 87.37  ? 698  HIS D O   1 
ATOM   13217 C CB  . HIS D 1 623 ? -63.117 3.264   2.845   1.00 83.41  ? 698  HIS D CB  1 
ATOM   13218 C CG  . HIS D 1 623 ? -62.758 2.057   2.037   1.00 85.05  ? 698  HIS D CG  1 
ATOM   13219 N ND1 . HIS D 1 623 ? -62.170 0.938   2.586   1.00 92.03  ? 698  HIS D ND1 1 
ATOM   13220 C CD2 . HIS D 1 623 ? -62.886 1.805   0.713   1.00 82.46  ? 698  HIS D CD2 1 
ATOM   13221 C CE1 . HIS D 1 623 ? -61.965 0.042   1.637   1.00 97.71  ? 698  HIS D CE1 1 
ATOM   13222 N NE2 . HIS D 1 623 ? -62.394 0.542   0.492   1.00 82.07  ? 698  HIS D NE2 1 
ATOM   13223 N N   . ASN D 1 624 ? -62.729 3.803   6.069   1.00 81.00  ? 699  ASN D N   1 
ATOM   13224 C CA  . ASN D 1 624 ? -61.909 3.647   7.267   1.00 77.45  ? 699  ASN D CA  1 
ATOM   13225 C C   . ASN D 1 624 ? -62.540 2.665   8.252   1.00 83.53  ? 699  ASN D C   1 
ATOM   13226 O O   . ASN D 1 624 ? -61.838 1.837   8.846   1.00 75.45  ? 699  ASN D O   1 
ATOM   13227 C CB  . ASN D 1 624 ? -61.679 5.002   7.936   1.00 73.56  ? 699  ASN D CB  1 
ATOM   13228 C CG  . ASN D 1 624 ? -60.546 4.970   8.945   1.00 82.36  ? 699  ASN D CG  1 
ATOM   13229 O OD1 . ASN D 1 624 ? -59.940 3.925   9.183   1.00 90.11  ? 699  ASN D OD1 1 
ATOM   13230 N ND2 . ASN D 1 624 ? -60.254 6.118   9.544   1.00 80.99  ? 699  ASN D ND2 1 
ATOM   13231 N N   . ALA D 1 625 ? -63.860 2.734   8.434   1.00 83.26  ? 700  ALA D N   1 
ATOM   13232 C CA  . ALA D 1 625 ? -64.542 1.917   9.431   1.00 80.14  ? 700  ALA D CA  1 
ATOM   13233 C C   . ALA D 1 625 ? -65.300 0.731   8.847   1.00 84.43  ? 700  ALA D C   1 
ATOM   13234 O O   . ALA D 1 625 ? -65.820 -0.087  9.615   1.00 85.41  ? 700  ALA D O   1 
ATOM   13235 C CB  . ALA D 1 625 ? -65.522 2.782   10.240  1.00 76.52  ? 700  ALA D CB  1 
ATOM   13236 N N   . HIS D 1 626 ? -65.377 0.610   7.524   1.00 85.88  ? 701  HIS D N   1 
ATOM   13237 C CA  . HIS D 1 626 ? -66.182 -0.428  6.897   1.00 74.14  ? 701  HIS D CA  1 
ATOM   13238 C C   . HIS D 1 626 ? -65.408 -1.040  5.739   1.00 79.50  ? 701  HIS D C   1 
ATOM   13239 O O   . HIS D 1 626 ? -64.634 -0.359  5.061   1.00 85.75  ? 701  HIS D O   1 
ATOM   13240 C CB  . HIS D 1 626 ? -67.522 0.132   6.400   1.00 90.43  ? 701  HIS D CB  1 
ATOM   13241 C CG  . HIS D 1 626 ? -68.297 0.860   7.453   1.00 91.82  ? 701  HIS D CG  1 
ATOM   13242 N ND1 . HIS D 1 626 ? -68.581 2.206   7.371   1.00 81.97  ? 701  HIS D ND1 1 
ATOM   13243 C CD2 . HIS D 1 626 ? -68.845 0.431   8.615   1.00 84.03  ? 701  HIS D CD2 1 
ATOM   13244 C CE1 . HIS D 1 626 ? -69.270 2.575   8.436   1.00 87.22  ? 701  HIS D CE1 1 
ATOM   13245 N NE2 . HIS D 1 626 ? -69.444 1.517   9.206   1.00 88.19  ? 701  HIS D NE2 1 
ATOM   13246 N N   . ASP D 1 627 ? -65.626 -2.335  5.519   1.00 80.41  ? 702  ASP D N   1 
ATOM   13247 C CA  . ASP D 1 627 ? -64.959 -3.058  4.438   1.00 83.12  ? 702  ASP D CA  1 
ATOM   13248 C C   . ASP D 1 627 ? -65.688 -2.763  3.135   1.00 95.28  ? 702  ASP D C   1 
ATOM   13249 O O   . ASP D 1 627 ? -66.717 -3.371  2.832   1.00 91.55  ? 702  ASP D O   1 
ATOM   13250 C CB  . ASP D 1 627 ? -64.922 -4.554  4.730   1.00 70.07  ? 702  ASP D CB  1 
ATOM   13251 C CG  . ASP D 1 627 ? -63.938 -5.295  3.845   1.00 83.40  ? 702  ASP D CG  1 
ATOM   13252 O OD1 . ASP D 1 627 ? -63.319 -4.653  2.972   1.00 98.42  ? 702  ASP D OD1 1 
ATOM   13253 O OD2 . ASP D 1 627 ? -63.786 -6.522  4.022   1.00 85.91  ? 702  ASP D OD2 1 
ATOM   13254 N N   . LEU D 1 628 ? -65.154 -1.824  2.355   1.00 96.47  ? 703  LEU D N   1 
ATOM   13255 C CA  . LEU D 1 628 ? -65.712 -1.477  1.056   1.00 94.69  ? 703  LEU D CA  1 
ATOM   13256 C C   . LEU D 1 628 ? -64.973 -2.164  -0.086  1.00 105.28 ? 703  LEU D C   1 
ATOM   13257 O O   . LEU D 1 628 ? -65.049 -1.705  -1.231  1.00 111.50 ? 703  LEU D O   1 
ATOM   13258 C CB  . LEU D 1 628 ? -65.698 0.039   0.859   1.00 92.28  ? 703  LEU D CB  1 
ATOM   13259 C CG  . LEU D 1 628 ? -66.299 0.907   1.967   1.00 91.26  ? 703  LEU D CG  1 
ATOM   13260 C CD1 . LEU D 1 628 ? -66.534 2.325   1.465   1.00 79.88  ? 703  LEU D CD1 1 
ATOM   13261 C CD2 . LEU D 1 628 ? -67.588 0.304   2.499   1.00 79.02  ? 703  LEU D CD2 1 
ATOM   13262 N N   . SER D 1 629 ? -64.263 -3.258  0.207   1.00 100.69 ? 704  SER D N   1 
ATOM   13263 C CA  . SER D 1 629 ? -63.515 -3.967  -0.828  1.00 106.26 ? 704  SER D CA  1 
ATOM   13264 C C   . SER D 1 629 ? -64.436 -4.553  -1.890  1.00 111.28 ? 704  SER D C   1 
ATOM   13265 O O   . SER D 1 629 ? -64.003 -4.779  -3.026  1.00 115.36 ? 704  SER D O   1 
ATOM   13266 C CB  . SER D 1 629 ? -62.664 -5.071  -0.200  1.00 101.45 ? 704  SER D CB  1 
ATOM   13267 O OG  . SER D 1 629 ? -61.615 -4.527  0.583   1.00 107.72 ? 704  SER D OG  1 
ATOM   13268 N N   . LYS D 1 630 ? -65.698 -4.818  -1.538  1.00 103.21 ? 705  LYS D N   1 
ATOM   13269 C CA  . LYS D 1 630 ? -66.675 -5.242  -2.535  1.00 106.32 ? 705  LYS D CA  1 
ATOM   13270 C C   . LYS D 1 630 ? -66.736 -4.264  -3.699  1.00 102.18 ? 705  LYS D C   1 
ATOM   13271 O O   . LYS D 1 630 ? -66.826 -4.673  -4.863  1.00 116.44 ? 705  LYS D O   1 
ATOM   13272 C CB  . LYS D 1 630 ? -68.057 -5.377  -1.893  1.00 123.64 ? 705  LYS D CB  1 
ATOM   13273 C CG  . LYS D 1 630 ? -69.194 -5.518  -2.898  1.00 122.37 ? 705  LYS D CG  1 
ATOM   13274 C CD  . LYS D 1 630 ? -70.559 -5.383  -2.234  1.00 139.81 ? 705  LYS D CD  1 
ATOM   13275 C CE  . LYS D 1 630 ? -70.667 -6.230  -0.976  1.00 150.80 ? 705  LYS D CE  1 
ATOM   13276 N NZ  . LYS D 1 630 ? -70.465 -7.676  -1.263  1.00 152.99 ? 705  LYS D NZ  1 
ATOM   13277 N N   . TRP D 1 631 ? -66.679 -2.965  -3.406  1.00 99.98  ? 706  TRP D N   1 
ATOM   13278 C CA  . TRP D 1 631 ? -66.783 -1.954  -4.446  1.00 102.78 ? 706  TRP D CA  1 
ATOM   13279 C C   . TRP D 1 631 ? -65.469 -1.707  -5.176  1.00 101.26 ? 706  TRP D C   1 
ATOM   13280 O O   . TRP D 1 631 ? -65.478 -1.022  -6.204  1.00 111.39 ? 706  TRP D O   1 
ATOM   13281 C CB  . TRP D 1 631 ? -67.316 -0.645  -3.853  1.00 90.18  ? 706  TRP D CB  1 
ATOM   13282 C CG  . TRP D 1 631 ? -68.754 -0.736  -3.416  1.00 97.68  ? 706  TRP D CG  1 
ATOM   13283 C CD1 . TRP D 1 631 ? -69.838 -0.231  -4.071  1.00 105.92 ? 706  TRP D CD1 1 
ATOM   13284 C CD2 . TRP D 1 631 ? -69.261 -1.362  -2.227  1.00 108.85 ? 706  TRP D CD2 1 
ATOM   13285 N NE1 . TRP D 1 631 ? -70.988 -0.506  -3.372  1.00 102.26 ? 706  TRP D NE1 1 
ATOM   13286 C CE2 . TRP D 1 631 ? -70.661 -1.199  -2.236  1.00 99.64  ? 706  TRP D CE2 1 
ATOM   13287 C CE3 . TRP D 1 631 ? -68.670 -2.042  -1.159  1.00 112.84 ? 706  TRP D CE3 1 
ATOM   13288 C CZ2 . TRP D 1 631 ? -71.477 -1.691  -1.220  1.00 88.63  ? 706  TRP D CZ2 1 
ATOM   13289 C CZ3 . TRP D 1 631 ? -69.483 -2.532  -0.152  1.00 102.35 ? 706  TRP D CZ3 1 
ATOM   13290 C CH2 . TRP D 1 631 ? -70.871 -2.353  -0.190  1.00 84.29  ? 706  TRP D CH2 1 
ATOM   13291 N N   . ASP D 1 632 ? -64.355 -2.242  -4.674  1.00 99.35  ? 707  ASP D N   1 
ATOM   13292 C CA  . ASP D 1 632 ? -63.079 -2.256  -5.391  1.00 108.71 ? 707  ASP D CA  1 
ATOM   13293 C C   . ASP D 1 632 ? -62.674 -0.851  -5.835  1.00 110.16 ? 707  ASP D C   1 
ATOM   13294 O O   . ASP D 1 632 ? -62.414 -0.591  -7.013  1.00 103.07 ? 707  ASP D O   1 
ATOM   13295 C CB  . ASP D 1 632 ? -63.144 -3.210  -6.585  1.00 100.61 ? 707  ASP D CB  1 
ATOM   13296 C CG  . ASP D 1 632 ? -61.785 -3.750  -6.977  1.00 129.72 ? 707  ASP D CG  1 
ATOM   13297 O OD1 . ASP D 1 632 ? -60.909 -2.947  -7.361  1.00 131.95 ? 707  ASP D OD1 1 
ATOM   13298 O OD2 . ASP D 1 632 ? -61.597 -4.983  -6.909  1.00 137.24 ? 707  ASP D OD2 1 
ATOM   13299 N N   . LEU D 1 633 ? -62.616 0.062   -4.870  1.00 105.56 ? 708  LEU D N   1 
ATOM   13300 C CA  . LEU D 1 633 ? -62.402 1.474   -5.155  1.00 107.78 ? 708  LEU D CA  1 
ATOM   13301 C C   . LEU D 1 633 ? -60.930 1.845   -5.274  1.00 106.48 ? 708  LEU D C   1 
ATOM   13302 O O   . LEU D 1 633 ? -60.620 3.030   -5.434  1.00 108.56 ? 708  LEU D O   1 
ATOM   13303 C CB  . LEU D 1 633 ? -63.053 2.335   -4.069  1.00 104.07 ? 708  LEU D CB  1 
ATOM   13304 C CG  . LEU D 1 633 ? -64.530 2.056   -3.785  1.00 110.07 ? 708  LEU D CG  1 
ATOM   13305 C CD1 . LEU D 1 633 ? -64.690 1.349   -2.443  1.00 101.72 ? 708  LEU D CD1 1 
ATOM   13306 C CD2 . LEU D 1 633 ? -65.361 3.327   -3.843  1.00 109.34 ? 708  LEU D CD2 1 
ATOM   13307 N N   . PHE D 1 634 ? -60.021 0.869   -5.198  1.00 98.62  ? 709  PHE D N   1 
ATOM   13308 C CA  . PHE D 1 634 ? -58.597 1.175   -5.290  1.00 106.49 ? 709  PHE D CA  1 
ATOM   13309 C C   . PHE D 1 634 ? -58.254 1.846   -6.613  1.00 103.51 ? 709  PHE D C   1 
ATOM   13310 O O   . PHE D 1 634 ? -57.433 2.771   -6.655  1.00 97.30  ? 709  PHE D O   1 
ATOM   13311 C CB  . PHE D 1 634 ? -57.772 -0.099  -5.116  1.00 109.35 ? 709  PHE D CB  1 
ATOM   13312 C CG  . PHE D 1 634 ? -56.289 0.142   -5.097  1.00 113.09 ? 709  PHE D CG  1 
ATOM   13313 C CD1 . PHE D 1 634 ? -55.689 0.809   -4.042  1.00 126.21 ? 709  PHE D CD1 1 
ATOM   13314 C CD2 . PHE D 1 634 ? -55.499 -0.278  -6.153  1.00 109.55 ? 709  PHE D CD2 1 
ATOM   13315 C CE1 . PHE D 1 634 ? -54.323 1.034   -4.033  1.00 122.30 ? 709  PHE D CE1 1 
ATOM   13316 C CE2 . PHE D 1 634 ? -54.137 -0.054  -6.152  1.00 112.08 ? 709  PHE D CE2 1 
ATOM   13317 C CZ  . PHE D 1 634 ? -53.547 0.602   -5.091  1.00 108.95 ? 709  PHE D CZ  1 
ATOM   13318 N N   . ALA D 1 635 ? -58.874 1.393   -7.706  1.00 102.86 ? 710  ALA D N   1 
ATOM   13319 C CA  . ALA D 1 635 ? -58.503 1.886   -9.028  1.00 98.33  ? 710  ALA D CA  1 
ATOM   13320 C C   . ALA D 1 635 ? -58.788 3.375   -9.170  1.00 101.16 ? 710  ALA D C   1 
ATOM   13321 O O   . ALA D 1 635 ? -57.975 4.116   -9.731  1.00 106.03 ? 710  ALA D O   1 
ATOM   13322 C CB  . ALA D 1 635 ? -59.235 1.089   -10.106 1.00 78.62  ? 710  ALA D CB  1 
ATOM   13323 N N   . CYS D 1 636 ? -59.937 3.832   -8.668  1.00 93.14  ? 711  CYS D N   1 
ATOM   13324 C CA  . CYS D 1 636 ? -60.277 5.248   -8.767  1.00 98.48  ? 711  CYS D CA  1 
ATOM   13325 C C   . CYS D 1 636 ? -59.248 6.108   -8.043  1.00 106.09 ? 711  CYS D C   1 
ATOM   13326 O O   . CYS D 1 636 ? -58.728 7.082   -8.602  1.00 112.74 ? 711  CYS D O   1 
ATOM   13327 C CB  . CYS D 1 636 ? -61.678 5.488   -8.205  1.00 100.53 ? 711  CYS D CB  1 
ATOM   13328 S SG  . CYS D 1 636 ? -62.952 4.410   -8.898  1.00 100.28 ? 711  CYS D SG  1 
ATOM   13329 N N   . ASN D 1 637 ? -58.934 5.751   -6.795  1.00 105.79 ? 712  ASN D N   1 
ATOM   13330 C CA  . ASN D 1 637 ? -57.978 6.528   -6.014  1.00 102.68 ? 712  ASN D CA  1 
ATOM   13331 C C   . ASN D 1 637 ? -56.594 6.502   -6.648  1.00 109.94 ? 712  ASN D C   1 
ATOM   13332 O O   . ASN D 1 637 ? -55.902 7.525   -6.684  1.00 115.44 ? 712  ASN D O   1 
ATOM   13333 C CB  . ASN D 1 637 ? -57.921 5.998   -4.581  1.00 104.32 ? 712  ASN D CB  1 
ATOM   13334 C CG  . ASN D 1 637 ? -59.287 5.934   -3.930  1.00 99.63  ? 712  ASN D CG  1 
ATOM   13335 O OD1 . ASN D 1 637 ? -59.979 6.946   -3.812  1.00 87.61  ? 712  ASN D OD1 1 
ATOM   13336 N ND2 . ASN D 1 637 ? -59.689 4.739   -3.513  1.00 96.69  ? 712  ASN D ND2 1 
ATOM   13337 N N   . TYR D 1 638 ? -56.178 5.344   -7.163  1.00 110.14 ? 713  TYR D N   1 
ATOM   13338 C CA  . TYR D 1 638 ? -54.854 5.229   -7.769  1.00 112.17 ? 713  TYR D CA  1 
ATOM   13339 C C   . TYR D 1 638 ? -54.755 6.065   -9.041  1.00 113.70 ? 713  TYR D C   1 
ATOM   13340 O O   . TYR D 1 638 ? -53.756 6.765   -9.262  1.00 110.72 ? 713  TYR D O   1 
ATOM   13341 C CB  . TYR D 1 638 ? -54.544 3.761   -8.063  1.00 106.08 ? 713  TYR D CB  1 
ATOM   13342 C CG  . TYR D 1 638 ? -53.567 3.552   -9.197  1.00 121.45 ? 713  TYR D CG  1 
ATOM   13343 C CD1 . TYR D 1 638 ? -52.246 3.975   -9.096  1.00 118.46 ? 713  TYR D CD1 1 
ATOM   13344 C CD2 . TYR D 1 638 ? -53.968 2.938   -10.376 1.00 125.20 ? 713  TYR D CD2 1 
ATOM   13345 C CE1 . TYR D 1 638 ? -51.354 3.788   -10.135 1.00 116.01 ? 713  TYR D CE1 1 
ATOM   13346 C CE2 . TYR D 1 638 ? -53.084 2.746   -11.420 1.00 123.32 ? 713  TYR D CE2 1 
ATOM   13347 C CZ  . TYR D 1 638 ? -51.779 3.173   -11.294 1.00 118.88 ? 713  TYR D CZ  1 
ATOM   13348 O OH  . TYR D 1 638 ? -50.894 2.985   -12.330 1.00 126.44 ? 713  TYR D OH  1 
ATOM   13349 N N   . LYS D 1 639 ? -55.772 5.976   -9.903  1.00 116.65 ? 714  LYS D N   1 
ATOM   13350 C CA  . LYS D 1 639 ? -55.805 6.803   -11.103 1.00 120.13 ? 714  LYS D CA  1 
ATOM   13351 C C   . LYS D 1 639 ? -55.771 8.279   -10.742 1.00 122.25 ? 714  LYS D C   1 
ATOM   13352 O O   . LYS D 1 639 ? -55.036 9.060   -11.356 1.00 131.28 ? 714  LYS D O   1 
ATOM   13353 C CB  . LYS D 1 639 ? -57.051 6.481   -11.928 1.00 110.14 ? 714  LYS D CB  1 
ATOM   13354 C CG  . LYS D 1 639 ? -57.043 5.108   -12.587 1.00 121.32 ? 714  LYS D CG  1 
ATOM   13355 C CD  . LYS D 1 639 ? -58.334 4.869   -13.355 1.00 109.99 ? 714  LYS D CD  1 
ATOM   13356 C CE  . LYS D 1 639 ? -58.428 5.770   -14.577 1.00 112.71 ? 714  LYS D CE  1 
ATOM   13357 N NZ  . LYS D 1 639 ? -59.732 5.620   -15.283 1.00 107.94 ? 714  LYS D NZ  1 
ATOM   13358 N N   . LEU D 1 640 ? -56.546 8.675   -9.731  1.00 114.91 ? 715  LEU D N   1 
ATOM   13359 C CA  . LEU D 1 640 ? -56.569 10.071  -9.316  1.00 116.85 ? 715  LEU D CA  1 
ATOM   13360 C C   . LEU D 1 640 ? -55.209 10.514  -8.788  1.00 113.07 ? 715  LEU D C   1 
ATOM   13361 O O   . LEU D 1 640 ? -54.766 11.637  -9.054  1.00 112.09 ? 715  LEU D O   1 
ATOM   13362 C CB  . LEU D 1 640 ? -57.660 10.268  -8.265  1.00 110.58 ? 715  LEU D CB  1 
ATOM   13363 C CG  . LEU D 1 640 ? -58.057 11.690  -7.889  1.00 118.75 ? 715  LEU D CG  1 
ATOM   13364 C CD1 . LEU D 1 640 ? -59.549 11.746  -7.621  1.00 111.43 ? 715  LEU D CD1 1 
ATOM   13365 C CD2 . LEU D 1 640 ? -57.267 12.138  -6.672  1.00 137.68 ? 715  LEU D CD2 1 
ATOM   13366 N N   . LEU D 1 641 ? -54.520 9.636   -8.057  1.00 108.92 ? 716  LEU D N   1 
ATOM   13367 C CA  . LEU D 1 641 ? -53.226 9.994   -7.484  1.00 121.26 ? 716  LEU D CA  1 
ATOM   13368 C C   . LEU D 1 641 ? -52.166 10.156  -8.567  1.00 124.27 ? 716  LEU D C   1 
ATOM   13369 O O   . LEU D 1 641 ? -51.405 11.133  -8.568  1.00 130.66 ? 716  LEU D O   1 
ATOM   13370 C CB  . LEU D 1 641 ? -52.798 8.938   -6.463  1.00 122.17 ? 716  LEU D CB  1 
ATOM   13371 C CG  . LEU D 1 641 ? -53.530 8.935   -5.119  1.00 102.96 ? 716  LEU D CG  1 
ATOM   13372 C CD1 . LEU D 1 641 ? -53.080 7.759   -4.264  1.00 98.36  ? 716  LEU D CD1 1 
ATOM   13373 C CD2 . LEU D 1 641 ? -53.329 10.249  -4.380  1.00 101.62 ? 716  LEU D CD2 1 
ATOM   13374 N N   . LYS D 1 642 ? -52.094 9.204   -9.501  1.00 120.99 ? 717  LYS D N   1 
ATOM   13375 C CA  . LYS D 1 642 ? -51.118 9.338   -10.578 1.00 125.54 ? 717  LYS D CA  1 
ATOM   13376 C C   . LYS D 1 642 ? -51.460 10.506  -11.498 1.00 122.04 ? 717  LYS D C   1 
ATOM   13377 O O   . LYS D 1 642 ? -50.554 11.179  -12.012 1.00 129.42 ? 717  LYS D O   1 
ATOM   13378 C CB  . LYS D 1 642 ? -51.003 8.025   -11.357 1.00 109.63 ? 717  LYS D CB  1 
ATOM   13379 C CG  . LYS D 1 642 ? -52.271 7.559   -12.044 1.00 119.23 ? 717  LYS D CG  1 
ATOM   13380 C CD  . LYS D 1 642 ? -51.959 6.452   -13.040 1.00 128.12 ? 717  LYS D CD  1 
ATOM   13381 C CE  . LYS D 1 642 ? -53.213 5.950   -13.740 1.00 135.92 ? 717  LYS D CE  1 
ATOM   13382 N NZ  . LYS D 1 642 ? -53.941 7.041   -14.446 1.00 130.57 ? 717  LYS D NZ  1 
ATOM   13383 N N   . THR D 1 643 ? -52.751 10.793  -11.683 1.00 122.92 ? 718  THR D N   1 
ATOM   13384 C CA  . THR D 1 643 ? -53.146 11.968  -12.451 1.00 129.78 ? 718  THR D CA  1 
ATOM   13385 C C   . THR D 1 643 ? -52.728 13.250  -11.744 1.00 134.04 ? 718  THR D C   1 
ATOM   13386 O O   . THR D 1 643 ? -52.337 14.225  -12.393 1.00 155.94 ? 718  THR D O   1 
ATOM   13387 C CB  . THR D 1 643 ? -54.657 11.955  -12.683 1.00 122.71 ? 718  THR D CB  1 
ATOM   13388 O OG1 . THR D 1 643 ? -55.044 10.704  -13.266 1.00 126.21 ? 718  THR D OG1 1 
ATOM   13389 C CG2 . THR D 1 643 ? -55.069 13.089  -13.610 1.00 121.85 ? 718  THR D CG2 1 
ATOM   13390 N N   . GLY D 1 644 ? -52.814 13.271  -10.413 1.00 134.71 ? 719  GLY D N   1 
ATOM   13391 C CA  . GLY D 1 644 ? -52.338 14.429  -9.676  1.00 136.42 ? 719  GLY D CA  1 
ATOM   13392 C C   . GLY D 1 644 ? -50.833 14.585  -9.758  1.00 134.83 ? 719  GLY D C   1 
ATOM   13393 O O   . GLY D 1 644 ? -50.316 15.705  -9.782  1.00 135.23 ? 719  GLY D O   1 
ATOM   13394 N N   . ILE D 1 645 ? -50.111 13.464  -9.793  1.00 130.29 ? 720  ILE D N   1 
ATOM   13395 C CA  . ILE D 1 645 ? -48.665 13.520  -10.002 1.00 135.75 ? 720  ILE D CA  1 
ATOM   13396 C C   . ILE D 1 645 ? -48.351 14.142  -11.356 1.00 144.84 ? 720  ILE D C   1 
ATOM   13397 O O   . ILE D 1 645 ? -47.493 15.026  -11.472 1.00 144.15 ? 720  ILE D O   1 
ATOM   13398 C CB  . ILE D 1 645 ? -48.043 12.118  -9.869  1.00 127.21 ? 720  ILE D CB  1 
ATOM   13399 C CG1 . ILE D 1 645 ? -47.938 11.733  -8.395  1.00 134.86 ? 720  ILE D CG1 1 
ATOM   13400 C CG2 . ILE D 1 645 ? -46.677 12.069  -10.543 1.00 121.66 ? 720  ILE D CG2 1 
ATOM   13401 C CD1 . ILE D 1 645 ? -47.084 12.685  -7.593  1.00 132.96 ? 720  ILE D CD1 1 
ATOM   13402 N N   . GLU D 1 646 ? -49.049 13.694  -12.401 1.00 146.81 ? 721  GLU D N   1 
ATOM   13403 C CA  . GLU D 1 646 ? -48.759 14.188  -13.744 1.00 137.44 ? 721  GLU D CA  1 
ATOM   13404 C C   . GLU D 1 646 ? -49.162 15.651  -13.903 1.00 130.70 ? 721  GLU D C   1 
ATOM   13405 O O   . GLU D 1 646 ? -48.346 16.488  -14.308 1.00 135.77 ? 721  GLU D O   1 
ATOM   13406 C CB  . GLU D 1 646 ? -49.459 13.316  -14.785 1.00 131.76 ? 721  GLU D CB  1 
ATOM   13407 C CG  . GLU D 1 646 ? -49.042 11.858  -14.733 1.00 136.10 ? 721  GLU D CG  1 
ATOM   13408 C CD  . GLU D 1 646 ? -50.132 10.926  -15.212 1.00 151.87 ? 721  GLU D CD  1 
ATOM   13409 O OE1 . GLU D 1 646 ? -51.141 11.424  -15.754 1.00 140.24 ? 721  GLU D OE1 1 
ATOM   13410 O OE2 . GLU D 1 646 ? -49.977 9.697   -15.054 1.00 166.77 ? 721  GLU D OE2 1 
ATOM   13411 N N   . ASN D 1 647 ? -50.416 15.980  -13.589 1.00 137.12 ? 722  ASN D N   1 
ATOM   13412 C CA  . ASN D 1 647 ? -50.905 17.341  -13.791 1.00 145.79 ? 722  ASN D CA  1 
ATOM   13413 C C   . ASN D 1 647 ? -50.229 18.324  -12.842 1.00 144.36 ? 722  ASN D C   1 
ATOM   13414 O O   . ASN D 1 647 ? -49.713 19.362  -13.272 1.00 154.56 ? 722  ASN D O   1 
ATOM   13415 C CB  . ASN D 1 647 ? -52.423 17.385  -13.609 1.00 153.68 ? 722  ASN D CB  1 
ATOM   13416 C CG  . ASN D 1 647 ? -53.150 16.459  -14.560 1.00 152.57 ? 722  ASN D CG  1 
ATOM   13417 O OD1 . ASN D 1 647 ? -52.527 15.716  -15.318 1.00 146.44 ? 722  ASN D OD1 1 
ATOM   13418 N ND2 . ASN D 1 647 ? -54.477 16.494  -14.521 1.00 153.55 ? 722  ASN D ND2 1 
ATOM   13419 N N   . GLY D 1 648 ? -50.227 18.019  -11.548 1.00 138.18 ? 723  GLY D N   1 
ATOM   13420 C CA  . GLY D 1 648 ? -49.730 18.952  -10.561 1.00 148.06 ? 723  GLY D CA  1 
ATOM   13421 C C   . GLY D 1 648 ? -50.698 20.052  -10.186 1.00 144.50 ? 723  GLY D C   1 
ATOM   13422 O O   . GLY D 1 648 ? -50.347 20.909  -9.365  1.00 142.99 ? 723  GLY D O   1 
ATOM   13423 N N   . ASP D 1 649 ? -51.895 20.064  -10.770 1.00 146.69 ? 724  ASP D N   1 
ATOM   13424 C CA  . ASP D 1 649 ? -52.947 21.002  -10.406 1.00 153.42 ? 724  ASP D CA  1 
ATOM   13425 C C   . ASP D 1 649 ? -54.062 20.343  -9.609  1.00 152.10 ? 724  ASP D C   1 
ATOM   13426 O O   . ASP D 1 649 ? -55.048 21.011  -9.279  1.00 148.71 ? 724  ASP D O   1 
ATOM   13427 C CB  . ASP D 1 649 ? -53.530 21.658  -11.664 1.00 154.13 ? 724  ASP D CB  1 
ATOM   13428 C CG  . ASP D 1 649 ? -53.810 20.654  -12.766 1.00 159.02 ? 724  ASP D CG  1 
ATOM   13429 O OD1 . ASP D 1 649 ? -54.669 19.769  -12.567 1.00 142.04 ? 724  ASP D OD1 1 
ATOM   13430 O OD2 . ASP D 1 649 ? -53.167 20.749  -13.833 1.00 166.93 ? 724  ASP D OD2 1 
ATOM   13431 N N   . MET D 1 650 ? -53.934 19.056  -9.306  1.00 151.60 ? 725  MET D N   1 
ATOM   13432 C CA  . MET D 1 650 ? -54.956 18.350  -8.551  1.00 126.32 ? 725  MET D CA  1 
ATOM   13433 C C   . MET D 1 650 ? -55.082 18.967  -7.162  1.00 119.39 ? 725  MET D C   1 
ATOM   13434 O O   . MET D 1 650 ? -54.061 19.198  -6.500  1.00 127.37 ? 725  MET D O   1 
ATOM   13435 C CB  . MET D 1 650 ? -54.594 16.869  -8.444  1.00 105.45 ? 725  MET D CB  1 
ATOM   13436 C CG  . MET D 1 650 ? -55.602 16.009  -7.708  1.00 109.86 ? 725  MET D CG  1 
ATOM   13437 S SD  . MET D 1 650 ? -57.089 15.704  -8.677  1.00 118.63 ? 725  MET D SD  1 
ATOM   13438 C CE  . MET D 1 650 ? -56.496 14.446  -9.806  1.00 117.32 ? 725  MET D CE  1 
ATOM   13439 N N   . PRO D 1 651 ? -56.295 19.262  -6.693  1.00 112.62 ? 726  PRO D N   1 
ATOM   13440 C CA  . PRO D 1 651 ? -56.443 19.891  -5.373  1.00 121.69 ? 726  PRO D CA  1 
ATOM   13441 C C   . PRO D 1 651 ? -55.848 19.026  -4.271  1.00 124.27 ? 726  PRO D C   1 
ATOM   13442 O O   . PRO D 1 651 ? -55.948 17.798  -4.297  1.00 124.25 ? 726  PRO D O   1 
ATOM   13443 C CB  . PRO D 1 651 ? -57.961 20.041  -5.216  1.00 119.41 ? 726  PRO D CB  1 
ATOM   13444 C CG  . PRO D 1 651 ? -58.507 19.970  -6.605  1.00 110.33 ? 726  PRO D CG  1 
ATOM   13445 C CD  . PRO D 1 651 ? -57.589 19.070  -7.370  1.00 101.69 ? 726  PRO D CD  1 
ATOM   13446 N N   . GLU D 1 652 ? -55.216 19.688  -3.297  1.00 105.51 ? 727  GLU D N   1 
ATOM   13447 C CA  . GLU D 1 652 ? -54.512 18.962  -2.244  1.00 109.86 ? 727  GLU D CA  1 
ATOM   13448 C C   . GLU D 1 652 ? -55.459 18.065  -1.456  1.00 112.92 ? 727  GLU D C   1 
ATOM   13449 O O   . GLU D 1 652 ? -55.091 16.949  -1.069  1.00 118.07 ? 727  GLU D O   1 
ATOM   13450 C CB  . GLU D 1 652 ? -53.803 19.941  -1.308  1.00 107.91 ? 727  GLU D CB  1 
ATOM   13451 C CG  . GLU D 1 652 ? -54.699 21.037  -0.746  1.00 122.15 ? 727  GLU D CG  1 
ATOM   13452 C CD  . GLU D 1 652 ? -54.102 21.701  0.480   1.00 121.00 ? 727  GLU D CD  1 
ATOM   13453 O OE1 . GLU D 1 652 ? -53.925 21.005  1.502   1.00 113.72 ? 727  GLU D OE1 1 
ATOM   13454 O OE2 . GLU D 1 652 ? -53.806 22.914  0.424   1.00 128.80 ? 727  GLU D OE2 1 
ATOM   13455 N N   . GLN D 1 653 ? -56.685 18.535  -1.211  1.00 107.72 ? 728  GLN D N   1 
ATOM   13456 C CA  . GLN D 1 653 ? -57.636 17.763  -0.417  1.00 104.94 ? 728  GLN D CA  1 
ATOM   13457 C C   . GLN D 1 653 ? -57.988 16.451  -1.103  1.00 105.28 ? 728  GLN D C   1 
ATOM   13458 O O   . GLN D 1 653 ? -58.124 15.409  -0.447  1.00 103.03 ? 728  GLN D O   1 
ATOM   13459 C CB  . GLN D 1 653 ? -58.898 18.588  -0.169  1.00 99.66  ? 728  GLN D CB  1 
ATOM   13460 C CG  . GLN D 1 653 ? -58.675 19.796  0.716   1.00 104.07 ? 728  GLN D CG  1 
ATOM   13461 C CD  . GLN D 1 653 ? -58.019 19.429  2.026   1.00 111.20 ? 728  GLN D CD  1 
ATOM   13462 O OE1 . GLN D 1 653 ? -56.919 19.886  2.333   1.00 116.05 ? 728  GLN D OE1 1 
ATOM   13463 N NE2 . GLN D 1 653 ? -58.691 18.593  2.808   1.00 116.32 ? 728  GLN D NE2 1 
ATOM   13464 N N   . ILE D 1 654 ? -58.138 16.486  -2.428  1.00 105.48 ? 729  ILE D N   1 
ATOM   13465 C CA  . ILE D 1 654 ? -58.487 15.279  -3.166  1.00 113.15 ? 729  ILE D CA  1 
ATOM   13466 C C   . ILE D 1 654 ? -57.348 14.271  -3.092  1.00 106.96 ? 729  ILE D C   1 
ATOM   13467 O O   . ILE D 1 654 ? -57.575 13.071  -2.901  1.00 103.13 ? 729  ILE D O   1 
ATOM   13468 C CB  . ILE D 1 654 ? -58.846 15.632  -4.620  1.00 108.89 ? 729  ILE D CB  1 
ATOM   13469 C CG1 . ILE D 1 654 ? -59.832 16.800  -4.652  1.00 123.73 ? 729  ILE D CG1 1 
ATOM   13470 C CG2 . ILE D 1 654 ? -59.483 14.447  -5.298  1.00 106.21 ? 729  ILE D CG2 1 
ATOM   13471 C CD1 . ILE D 1 654 ? -60.527 16.983  -5.987  1.00 118.27 ? 729  ILE D CD1 1 
ATOM   13472 N N   . VAL D 1 655 ? -56.105 14.746  -3.222  1.00 104.18 ? 730  VAL D N   1 
ATOM   13473 C CA  . VAL D 1 655 ? -54.943 13.871  -3.077  1.00 102.27 ? 730  VAL D CA  1 
ATOM   13474 C C   . VAL D 1 655 ? -54.907 13.257  -1.684  1.00 105.78 ? 730  VAL D C   1 
ATOM   13475 O O   . VAL D 1 655 ? -54.651 12.058  -1.523  1.00 99.14  ? 730  VAL D O   1 
ATOM   13476 C CB  . VAL D 1 655 ? -53.647 14.647  -3.379  1.00 102.00 ? 730  VAL D CB  1 
ATOM   13477 C CG1 . VAL D 1 655 ? -52.428 13.823  -2.991  1.00 98.33  ? 730  VAL D CG1 1 
ATOM   13478 C CG2 . VAL D 1 655 ? -53.586 15.028  -4.847  1.00 104.12 ? 730  VAL D CG2 1 
ATOM   13479 N N   . ILE D 1 656 ? -55.165 14.070  -0.659  1.00 109.52 ? 731  ILE D N   1 
ATOM   13480 C CA  . ILE D 1 656 ? -55.118 13.595  0.722   1.00 89.74  ? 731  ILE D CA  1 
ATOM   13481 C C   . ILE D 1 656 ? -56.131 12.475  0.934   1.00 93.71  ? 731  ILE D C   1 
ATOM   13482 O O   . ILE D 1 656 ? -55.795 11.380  1.413   1.00 92.05  ? 731  ILE D O   1 
ATOM   13483 C CB  . ILE D 1 656 ? -55.364 14.768  1.689   1.00 77.29  ? 731  ILE D CB  1 
ATOM   13484 C CG1 . ILE D 1 656 ? -54.156 15.706  1.704   1.00 90.39  ? 731  ILE D CG1 1 
ATOM   13485 C CG2 . ILE D 1 656 ? -55.683 14.256  3.084   1.00 83.95  ? 731  ILE D CG2 1 
ATOM   13486 C CD1 . ILE D 1 656 ? -54.439 17.054  2.328   1.00 98.63  ? 731  ILE D CD1 1 
ATOM   13487 N N   . HIS D 1 657 ? -57.391 12.735  0.572   1.00 91.85  ? 732  HIS D N   1 
ATOM   13488 C CA  . HIS D 1 657 ? -58.434 11.741  0.801   1.00 91.06  ? 732  HIS D CA  1 
ATOM   13489 C C   . HIS D 1 657 ? -58.257 10.509  -0.081  1.00 91.15  ? 732  HIS D C   1 
ATOM   13490 O O   . HIS D 1 657 ? -58.592 9.398   0.345   1.00 88.23  ? 732  HIS D O   1 
ATOM   13491 C CB  . HIS D 1 657 ? -59.813 12.367  0.595   1.00 85.63  ? 732  HIS D CB  1 
ATOM   13492 C CG  . HIS D 1 657 ? -60.129 13.461  1.567   1.00 80.49  ? 732  HIS D CG  1 
ATOM   13493 N ND1 . HIS D 1 657 ? -60.076 14.796  1.230   1.00 96.68  ? 732  HIS D ND1 1 
ATOM   13494 C CD2 . HIS D 1 657 ? -60.509 13.417  2.867   1.00 78.26  ? 732  HIS D CD2 1 
ATOM   13495 C CE1 . HIS D 1 657 ? -60.405 15.528  2.281   1.00 92.57  ? 732  HIS D CE1 1 
ATOM   13496 N NE2 . HIS D 1 657 ? -60.673 14.715  3.287   1.00 90.58  ? 732  HIS D NE2 1 
ATOM   13497 N N   . ALA D 1 658 ? -57.711 10.668  -1.292  1.00 86.71  ? 733  ALA D N   1 
ATOM   13498 C CA  . ALA D 1 658 ? -57.446 9.503   -2.131  1.00 93.83  ? 733  ALA D CA  1 
ATOM   13499 C C   . ALA D 1 658 ? -56.341 8.639   -1.539  1.00 92.86  ? 733  ALA D C   1 
ATOM   13500 O O   . ALA D 1 658 ? -56.430 7.404   -1.558  1.00 91.84  ? 733  ALA D O   1 
ATOM   13501 C CB  . ALA D 1 658 ? -57.086 9.951   -3.546  1.00 98.42  ? 733  ALA D CB  1 
ATOM   13502 N N   . LEU D 1 659 ? -55.286 9.274   -1.018  1.00 88.43  ? 734  LEU D N   1 
ATOM   13503 C CA  . LEU D 1 659 ? -54.253 8.539   -0.298  1.00 83.84  ? 734  LEU D CA  1 
ATOM   13504 C C   . LEU D 1 659 ? -54.862 7.733   0.840   1.00 92.73  ? 734  LEU D C   1 
ATOM   13505 O O   . LEU D 1 659 ? -54.610 6.527   0.971   1.00 83.98  ? 734  LEU D O   1 
ATOM   13506 C CB  . LEU D 1 659 ? -53.200 9.511   0.238   1.00 83.72  ? 734  LEU D CB  1 
ATOM   13507 C CG  . LEU D 1 659 ? -52.202 10.115  -0.751  1.00 80.18  ? 734  LEU D CG  1 
ATOM   13508 C CD1 . LEU D 1 659 ? -51.453 11.268  -0.102  1.00 77.72  ? 734  LEU D CD1 1 
ATOM   13509 C CD2 . LEU D 1 659 ? -51.231 9.062   -1.262  1.00 85.60  ? 734  LEU D CD2 1 
ATOM   13510 N N   . GLN D 1 660 ? -55.687 8.388   1.663   1.00 93.50  ? 735  GLN D N   1 
ATOM   13511 C CA  . GLN D 1 660 ? -56.309 7.696   2.791   1.00 83.46  ? 735  GLN D CA  1 
ATOM   13512 C C   . GLN D 1 660 ? -57.163 6.523   2.320   1.00 84.75  ? 735  GLN D C   1 
ATOM   13513 O O   . GLN D 1 660 ? -57.110 5.429   2.899   1.00 86.36  ? 735  GLN D O   1 
ATOM   13514 C CB  . GLN D 1 660 ? -57.152 8.668   3.616   1.00 75.74  ? 735  GLN D CB  1 
ATOM   13515 C CG  . GLN D 1 660 ? -56.371 9.792   4.273   1.00 80.47  ? 735  GLN D CG  1 
ATOM   13516 C CD  . GLN D 1 660 ? -57.258 10.682  5.123   1.00 83.48  ? 735  GLN D CD  1 
ATOM   13517 O OE1 . GLN D 1 660 ? -58.415 10.350  5.392   1.00 78.09  ? 735  GLN D OE1 1 
ATOM   13518 N NE2 . GLN D 1 660 ? -56.719 11.814  5.557   1.00 87.59  ? 735  GLN D NE2 1 
ATOM   13519 N N   . CYS D 1 661 ? -57.955 6.730   1.266   1.00 80.66  ? 736  CYS D N   1 
ATOM   13520 C CA  . CYS D 1 661 ? -58.888 5.695   0.834   1.00 87.46  ? 736  CYS D CA  1 
ATOM   13521 C C   . CYS D 1 661 ? -58.155 4.491   0.255   1.00 92.12  ? 736  CYS D C   1 
ATOM   13522 O O   . CYS D 1 661 ? -58.519 3.344   0.540   1.00 90.42  ? 736  CYS D O   1 
ATOM   13523 C CB  . CYS D 1 661 ? -59.878 6.267   -0.179  1.00 86.32  ? 736  CYS D CB  1 
ATOM   13524 S SG  . CYS D 1 661 ? -61.390 5.290   -0.341  1.00 83.87  ? 736  CYS D SG  1 
ATOM   13525 N N   . ALA D 1 662 ? -57.123 4.726   -0.558  1.00 83.92  ? 737  ALA D N   1 
ATOM   13526 C CA  . ALA D 1 662 ? -56.331 3.612   -1.070  1.00 83.03  ? 737  ALA D CA  1 
ATOM   13527 C C   . ALA D 1 662 ? -55.632 2.873   0.065   1.00 95.05  ? 737  ALA D C   1 
ATOM   13528 O O   . ALA D 1 662 ? -55.517 1.637   0.042   1.00 96.05  ? 737  ALA D O   1 
ATOM   13529 C CB  . ALA D 1 662 ? -55.317 4.119   -2.094  1.00 82.86  ? 737  ALA D CB  1 
ATOM   13530 N N   . HIS D 1 663 ? -55.163 3.617   1.072   1.00 89.91  ? 738  HIS D N   1 
ATOM   13531 C CA  . HIS D 1 663 ? -54.574 2.999   2.255   1.00 88.04  ? 738  HIS D CA  1 
ATOM   13532 C C   . HIS D 1 663 ? -55.563 2.049   2.925   1.00 88.86  ? 738  HIS D C   1 
ATOM   13533 O O   . HIS D 1 663 ? -55.223 0.902   3.250   1.00 90.24  ? 738  HIS D O   1 
ATOM   13534 C CB  . HIS D 1 663 ? -54.120 4.103   3.213   1.00 82.38  ? 738  HIS D CB  1 
ATOM   13535 C CG  . HIS D 1 663 ? -53.579 3.606   4.514   1.00 84.91  ? 738  HIS D CG  1 
ATOM   13536 N ND1 . HIS D 1 663 ? -52.500 2.753   4.597   1.00 85.76  ? 738  HIS D ND1 1 
ATOM   13537 C CD2 . HIS D 1 663 ? -53.954 3.864   5.789   1.00 86.48  ? 738  HIS D CD2 1 
ATOM   13538 C CE1 . HIS D 1 663 ? -52.243 2.495   5.867   1.00 90.70  ? 738  HIS D CE1 1 
ATOM   13539 N NE2 . HIS D 1 663 ? -53.110 3.157   6.611   1.00 88.81  ? 738  HIS D NE2 1 
ATOM   13540 N N   . TYR D 1 664 ? -56.806 2.507   3.117   1.00 87.34  ? 739  TYR D N   1 
ATOM   13541 C CA  . TYR D 1 664 ? -57.817 1.654   3.742   1.00 87.64  ? 739  TYR D CA  1 
ATOM   13542 C C   . TYR D 1 664 ? -58.150 0.449   2.870   1.00 89.39  ? 739  TYR D C   1 
ATOM   13543 O O   . TYR D 1 664 ? -58.403 -0.645  3.389   1.00 88.07  ? 739  TYR D O   1 
ATOM   13544 C CB  . TYR D 1 664 ? -59.093 2.442   4.044   1.00 79.08  ? 739  TYR D CB  1 
ATOM   13545 C CG  . TYR D 1 664 ? -58.893 3.730   4.804   1.00 76.53  ? 739  TYR D CG  1 
ATOM   13546 C CD1 . TYR D 1 664 ? -58.019 3.799   5.881   1.00 70.62  ? 739  TYR D CD1 1 
ATOM   13547 C CD2 . TYR D 1 664 ? -59.617 4.867   4.474   1.00 77.11  ? 739  TYR D CD2 1 
ATOM   13548 C CE1 . TYR D 1 664 ? -57.844 4.977   6.584   1.00 65.90  ? 739  TYR D CE1 1 
ATOM   13549 C CE2 . TYR D 1 664 ? -59.451 6.044   5.172   1.00 81.98  ? 739  TYR D CE2 1 
ATOM   13550 C CZ  . TYR D 1 664 ? -58.566 6.096   6.225   1.00 81.21  ? 739  TYR D CZ  1 
ATOM   13551 O OH  . TYR D 1 664 ? -58.405 7.274   6.918   1.00 87.17  ? 739  TYR D OH  1 
ATOM   13552 N N   . VAL D 1 665 ? -58.186 0.637   1.547   1.00 87.15  ? 740  VAL D N   1 
ATOM   13553 C CA  . VAL D 1 665 ? -58.424 -0.487  0.642   1.00 90.73  ? 740  VAL D CA  1 
ATOM   13554 C C   . VAL D 1 665 ? -57.373 -1.567  0.858   1.00 102.44 ? 740  VAL D C   1 
ATOM   13555 O O   . VAL D 1 665 ? -57.693 -2.754  1.028   1.00 98.25  ? 740  VAL D O   1 
ATOM   13556 C CB  . VAL D 1 665 ? -58.438 -0.014  -0.822  1.00 84.74  ? 740  VAL D CB  1 
ATOM   13557 C CG1 . VAL D 1 665 ? -58.535 -1.207  -1.754  1.00 103.25 ? 740  VAL D CG1 1 
ATOM   13558 C CG2 . VAL D 1 665 ? -59.592 0.937   -1.069  1.00 84.90  ? 740  VAL D CG2 1 
ATOM   13559 N N   . ILE D 1 666 ? -56.098 -1.166  0.851   1.00 96.15  ? 741  ILE D N   1 
ATOM   13560 C CA  . ILE D 1 666 ? -55.016 -2.129  1.039   1.00 91.14  ? 741  ILE D CA  1 
ATOM   13561 C C   . ILE D 1 666 ? -55.131 -2.814  2.395   1.00 97.33  ? 741  ILE D C   1 
ATOM   13562 O O   . ILE D 1 666 ? -54.924 -4.028  2.512   1.00 106.31 ? 741  ILE D O   1 
ATOM   13563 C CB  . ILE D 1 666 ? -53.648 -1.444  0.867   1.00 88.27  ? 741  ILE D CB  1 
ATOM   13564 C CG1 . ILE D 1 666 ? -53.520 -0.861  -0.538  1.00 91.65  ? 741  ILE D CG1 1 
ATOM   13565 C CG2 . ILE D 1 666 ? -52.517 -2.421  1.157   1.00 91.90  ? 741  ILE D CG2 1 
ATOM   13566 C CD1 . ILE D 1 666 ? -52.219 -0.145  -0.769  1.00 103.87 ? 741  ILE D CD1 1 
ATOM   13567 N N   . LEU D 1 667 ? -55.467 -2.053  3.441   1.00 93.26  ? 742  LEU D N   1 
ATOM   13568 C CA  . LEU D 1 667 ? -55.527 -2.642  4.777   1.00 84.86  ? 742  LEU D CA  1 
ATOM   13569 C C   . LEU D 1 667 ? -56.659 -3.660  4.886   1.00 88.66  ? 742  LEU D C   1 
ATOM   13570 O O   . LEU D 1 667 ? -56.491 -4.733  5.484   1.00 99.07  ? 742  LEU D O   1 
ATOM   13571 C CB  . LEU D 1 667 ? -55.684 -1.540  5.825   1.00 78.86  ? 742  LEU D CB  1 
ATOM   13572 C CG  . LEU D 1 667 ? -54.475 -0.621  6.024   1.00 75.56  ? 742  LEU D CG  1 
ATOM   13573 C CD1 . LEU D 1 667 ? -54.524 0.057   7.385   1.00 79.29  ? 742  LEU D CD1 1 
ATOM   13574 C CD2 . LEU D 1 667 ? -53.173 -1.389  5.856   1.00 70.39  ? 742  LEU D CD2 1 
ATOM   13575 N N   . TRP D 1 668 ? -57.820 -3.343  4.310   1.00 91.58  ? 743  TRP D N   1 
ATOM   13576 C CA  . TRP D 1 668 ? -58.945 -4.271  4.352   1.00 96.03  ? 743  TRP D CA  1 
ATOM   13577 C C   . TRP D 1 668 ? -58.631 -5.534  3.559   1.00 105.92 ? 743  TRP D C   1 
ATOM   13578 O O   . TRP D 1 668 ? -58.957 -6.654  3.986   1.00 112.58 ? 743  TRP D O   1 
ATOM   13579 C CB  . TRP D 1 668 ? -60.196 -3.585  3.804   1.00 88.00  ? 743  TRP D CB  1 
ATOM   13580 C CG  . TRP D 1 668 ? -60.905 -2.725  4.811   1.00 87.16  ? 743  TRP D CG  1 
ATOM   13581 C CD1 . TRP D 1 668 ? -61.070 -1.371  4.754   1.00 84.48  ? 743  TRP D CD1 1 
ATOM   13582 C CD2 . TRP D 1 668 ? -61.534 -3.154  6.025   1.00 85.43  ? 743  TRP D CD2 1 
ATOM   13583 N NE1 . TRP D 1 668 ? -61.767 -0.931  5.852   1.00 83.24  ? 743  TRP D NE1 1 
ATOM   13584 C CE2 . TRP D 1 668 ? -62.063 -2.006  6.648   1.00 85.22  ? 743  TRP D CE2 1 
ATOM   13585 C CE3 . TRP D 1 668 ? -61.703 -4.396  6.644   1.00 84.62  ? 743  TRP D CE3 1 
ATOM   13586 C CZ2 . TRP D 1 668 ? -62.750 -2.063  7.859   1.00 90.40  ? 743  TRP D CZ2 1 
ATOM   13587 C CZ3 . TRP D 1 668 ? -62.386 -4.450  7.846   1.00 72.85  ? 743  TRP D CZ3 1 
ATOM   13588 C CH2 . TRP D 1 668 ? -62.900 -3.292  8.440   1.00 86.22  ? 743  TRP D CH2 1 
ATOM   13589 N N   . GLN D 1 669 ? -57.977 -5.377  2.404   1.00 105.27 ? 744  GLN D N   1 
ATOM   13590 C CA  . GLN D 1 669 ? -57.546 -6.557  1.665   1.00 109.40 ? 744  GLN D CA  1 
ATOM   13591 C C   . GLN D 1 669 ? -56.547 -7.377  2.470   1.00 112.82 ? 744  GLN D C   1 
ATOM   13592 O O   . GLN D 1 669 ? -56.559 -8.606  2.399   1.00 130.15 ? 744  GLN D O   1 
ATOM   13593 C CB  . GLN D 1 669 ? -56.953 -6.175  0.313   1.00 114.10 ? 744  GLN D CB  1 
ATOM   13594 C CG  . GLN D 1 669 ? -57.954 -5.610  -0.667  1.00 111.99 ? 744  GLN D CG  1 
ATOM   13595 C CD  . GLN D 1 669 ? -57.676 -6.074  -2.081  1.00 121.00 ? 744  GLN D CD  1 
ATOM   13596 O OE1 . GLN D 1 669 ? -57.610 -7.274  -2.350  1.00 130.72 ? 744  GLN D OE1 1 
ATOM   13597 N NE2 . GLN D 1 669 ? -57.509 -5.126  -2.993  1.00 144.89 ? 744  GLN D NE2 1 
ATOM   13598 N N   . LEU D 1 670 ? -55.675 -6.720  3.240   1.00 108.67 ? 745  LEU D N   1 
ATOM   13599 C CA  . LEU D 1 670 ? -54.758 -7.466  4.100   1.00 116.02 ? 745  LEU D CA  1 
ATOM   13600 C C   . LEU D 1 670 ? -55.518 -8.262  5.151   1.00 116.35 ? 745  LEU D C   1 
ATOM   13601 O O   . LEU D 1 670 ? -55.143 -9.394  5.478   1.00 127.98 ? 745  LEU D O   1 
ATOM   13602 C CB  . LEU D 1 670 ? -53.760 -6.522  4.772   1.00 105.85 ? 745  LEU D CB  1 
ATOM   13603 C CG  . LEU D 1 670 ? -52.771 -7.226  5.706   1.00 96.59  ? 745  LEU D CG  1 
ATOM   13604 C CD1 . LEU D 1 670 ? -51.864 -8.170  4.928   1.00 110.68 ? 745  LEU D CD1 1 
ATOM   13605 C CD2 . LEU D 1 670 ? -51.954 -6.226  6.501   1.00 96.59  ? 745  LEU D CD2 1 
ATOM   13606 N N   . ALA D 1 671 ? -56.583 -7.677  5.701   1.00 107.12 ? 746  ALA D N   1 
ATOM   13607 C CA  . ALA D 1 671 ? -57.442 -8.429  6.612   1.00 104.46 ? 746  ALA D CA  1 
ATOM   13608 C C   . ALA D 1 671 ? -58.022 -9.661  5.925   1.00 123.21 ? 746  ALA D C   1 
ATOM   13609 O O   . ALA D 1 671 ? -58.114 -10.735 6.531   1.00 132.50 ? 746  ALA D O   1 
ATOM   13610 C CB  . ALA D 1 671 ? -58.558 -7.533  7.147   1.00 99.81  ? 746  ALA D CB  1 
ATOM   13611 N N   . LYS D 1 672 ? -58.408 -9.527  4.653   1.00 124.74 ? 747  LYS D N   1 
ATOM   13612 C CA  . LYS D 1 672 ? -58.955 -10.678 3.932   1.00 131.96 ? 747  LYS D CA  1 
ATOM   13613 C C   . LYS D 1 672 ? -57.884 -11.728 3.626   1.00 151.01 ? 747  LYS D C   1 
ATOM   13614 O O   . LYS D 1 672 ? -58.142 -12.932 3.743   1.00 164.18 ? 747  LYS D O   1 
ATOM   13615 C CB  . LYS D 1 672 ? -59.642 -10.225 2.643   1.00 136.37 ? 747  LYS D CB  1 
ATOM   13616 C CG  . LYS D 1 672 ? -61.004 -9.587  2.862   1.00 134.41 ? 747  LYS D CG  1 
ATOM   13617 C CD  . LYS D 1 672 ? -61.943 -9.875  1.703   1.00 133.96 ? 747  LYS D CD  1 
ATOM   13618 C CE  . LYS D 1 672 ? -61.501 -9.154  0.443   1.00 134.58 ? 747  LYS D CE  1 
ATOM   13619 N NZ  . LYS D 1 672 ? -61.941 -9.866  -0.788  1.00 143.72 ? 747  LYS D NZ  1 
ATOM   13620 N N   . ILE D 1 673 ? -56.682 -11.295 3.230   1.00 152.17 ? 748  ILE D N   1 
ATOM   13621 C CA  . ILE D 1 673 ? -55.617 -12.214 2.822   1.00 144.70 ? 748  ILE D CA  1 
ATOM   13622 C C   . ILE D 1 673 ? -55.152 -13.069 3.993   1.00 149.54 ? 748  ILE D C   1 
ATOM   13623 O O   . ILE D 1 673 ? -54.704 -14.207 3.801   1.00 158.91 ? 748  ILE D O   1 
ATOM   13624 C CB  . ILE D 1 673 ? -54.442 -11.433 2.197   1.00 136.06 ? 748  ILE D CB  1 
ATOM   13625 C CG1 . ILE D 1 673 ? -54.893 -10.645 0.965   1.00 155.79 ? 748  ILE D CG1 1 
ATOM   13626 C CG2 . ILE D 1 673 ? -53.296 -12.364 1.819   1.00 137.32 ? 748  ILE D CG2 1 
ATOM   13627 C CD1 . ILE D 1 673 ? -55.233 -11.502 -0.223  1.00 174.36 ? 748  ILE D CD1 1 
ATOM   13628 N N   . THR D 1 674 ? -55.257 -12.547 5.219   1.00 158.60 ? 749  THR D N   1 
ATOM   13629 C CA  . THR D 1 674 ? -54.879 -13.308 6.407   1.00 163.84 ? 749  THR D CA  1 
ATOM   13630 C C   . THR D 1 674 ? -55.579 -14.660 6.465   1.00 163.54 ? 749  THR D C   1 
ATOM   13631 O O   . THR D 1 674 ? -55.073 -15.589 7.105   1.00 162.21 ? 749  THR D O   1 
ATOM   13632 C CB  . THR D 1 674 ? -55.193 -12.489 7.665   1.00 161.72 ? 749  THR D CB  1 
ATOM   13633 O OG1 . THR D 1 674 ? -54.692 -11.155 7.505   1.00 157.98 ? 749  THR D OG1 1 
ATOM   13634 C CG2 . THR D 1 674 ? -54.546 -13.110 8.896   1.00 141.44 ? 749  THR D CG2 1 
ATOM   13635 N N   . GLU D 1 675 ? -56.724 -14.794 5.800   1.00 164.45 ? 750  GLU D N   1 
ATOM   13636 C CA  . GLU D 1 675 ? -57.429 -16.065 5.701   1.00 171.42 ? 750  GLU D CA  1 
ATOM   13637 C C   . GLU D 1 675 ? -56.866 -16.857 4.528   1.00 178.60 ? 750  GLU D C   1 
ATOM   13638 O O   . GLU D 1 675 ? -56.959 -16.418 3.376   1.00 182.82 ? 750  GLU D O   1 
ATOM   13639 C CB  . GLU D 1 675 ? -58.928 -15.838 5.519   1.00 164.84 ? 750  GLU D CB  1 
ATOM   13640 C CG  . GLU D 1 675 ? -59.467 -14.615 6.235   1.00 160.66 ? 750  GLU D CG  1 
ATOM   13641 C CD  . GLU D 1 675 ? -59.242 -14.672 7.730   1.00 176.97 ? 750  GLU D CD  1 
ATOM   13642 O OE1 . GLU D 1 675 ? -59.825 -15.563 8.384   1.00 184.41 ? 750  GLU D OE1 1 
ATOM   13643 O OE2 . GLU D 1 675 ? -58.486 -13.826 8.252   1.00 184.42 ? 750  GLU D OE2 1 
ATOM   13644 N N   . SER D 1 676 ? -56.277 -18.017 4.820   1.00 181.79 ? 751  SER D N   1 
ATOM   13645 C CA  . SER D 1 676 ? -55.816 -18.893 3.750   1.00 182.31 ? 751  SER D CA  1 
ATOM   13646 C C   . SER D 1 676 ? -56.984 -19.379 2.906   1.00 186.14 ? 751  SER D C   1 
ATOM   13647 O O   . SER D 1 676 ? -56.881 -19.475 1.676   1.00 207.88 ? 751  SER D O   1 
ATOM   13648 C CB  . SER D 1 676 ? -55.047 -20.074 4.339   1.00 177.21 ? 751  SER D CB  1 
ATOM   13649 O OG  . SER D 1 676 ? -55.897 -20.889 5.127   1.00 169.12 ? 751  SER D OG  1 
ATOM   13650 N N   . THR D 1 677 ? -58.109 -19.679 3.555   1.00 185.78 ? 752  THR D N   1 
ATOM   13651 C CA  . THR D 1 677 ? -59.297 -20.134 2.844   1.00 185.08 ? 752  THR D CA  1 
ATOM   13652 C C   . THR D 1 677 ? -59.797 -19.090 1.853   1.00 187.33 ? 752  THR D C   1 
ATOM   13653 O O   . THR D 1 677 ? -60.391 -19.443 0.828   1.00 191.60 ? 752  THR D O   1 
ATOM   13654 C CB  . THR D 1 677 ? -60.393 -20.475 3.853   1.00 176.51 ? 752  THR D CB  1 
ATOM   13655 O OG1 . THR D 1 677 ? -60.970 -19.264 4.358   1.00 174.60 ? 752  THR D OG1 1 
ATOM   13656 C CG2 . THR D 1 677 ? -59.807 -21.255 5.019   1.00 162.86 ? 752  THR D CG2 1 
ATOM   13657 N N   . SER D 1 678 ? -59.560 -17.807 2.134   1.00 187.56 ? 753  SER D N   1 
ATOM   13658 C CA  . SER D 1 678 ? -60.112 -16.750 1.292   1.00 192.38 ? 753  SER D CA  1 
ATOM   13659 C C   . SER D 1 678 ? -59.483 -16.759 -0.096  1.00 185.15 ? 753  SER D C   1 
ATOM   13660 O O   . SER D 1 678 ? -60.193 -16.822 -1.106  1.00 182.86 ? 753  SER D O   1 
ATOM   13661 C CB  . SER D 1 678 ? -59.924 -15.390 1.965   1.00 192.42 ? 753  SER D CB  1 
ATOM   13662 O OG  . SER D 1 678 ? -58.567 -14.982 1.946   1.00 199.17 ? 753  SER D OG  1 
ATOM   13663 N N   . THR D 1 679 ? -58.155 -16.699 -0.170  1.00 172.55 ? 754  THR D N   1 
ATOM   13664 C CA  . THR D 1 679 ? -57.477 -16.613 -1.458  1.00 168.31 ? 754  THR D CA  1 
ATOM   13665 C C   . THR D 1 679 ? -55.991 -16.881 -1.268  1.00 165.76 ? 754  THR D C   1 
ATOM   13666 O O   . THR D 1 679 ? -55.477 -16.906 -0.147  1.00 167.81 ? 754  THR D O   1 
ATOM   13667 C CB  . THR D 1 679 ? -57.697 -15.247 -2.113  1.00 169.44 ? 754  THR D CB  1 
ATOM   13668 O OG1 . THR D 1 679 ? -56.850 -15.119 -3.260  1.00 162.44 ? 754  THR D OG1 1 
ATOM   13669 C CG2 . THR D 1 679 ? -57.401 -14.132 -1.126  1.00 163.02 ? 754  THR D CG2 1 
ATOM   13670 N N   . LYS D 1 680 ? -55.308 -17.082 -2.396  1.00 159.46 ? 755  LYS D N   1 
ATOM   13671 C CA  . LYS D 1 680 ? -53.866 -17.296 -2.435  1.00 160.44 ? 755  LYS D CA  1 
ATOM   13672 C C   . LYS D 1 680 ? -53.203 -16.325 -3.406  1.00 158.07 ? 755  LYS D C   1 
ATOM   13673 O O   . LYS D 1 680 ? -52.215 -15.666 -3.063  1.00 152.70 ? 755  LYS D O   1 
ATOM   13674 C CB  . LYS D 1 680 ? -53.540 -18.735 -2.844  1.00 157.19 ? 755  LYS D CB  1 
ATOM   13675 C CG  . LYS D 1 680 ? -54.112 -19.818 -1.944  1.00 161.51 ? 755  LYS D CG  1 
ATOM   13676 C CD  . LYS D 1 680 ? -53.579 -19.683 -0.531  1.00 153.23 ? 755  LYS D CD  1 
ATOM   13677 C CE  . LYS D 1 680 ? -53.912 -20.899 0.316   1.00 150.46 ? 755  LYS D CE  1 
ATOM   13678 N NZ  . LYS D 1 680 ? -55.365 -21.214 0.278   1.00 153.31 ? 755  LYS D NZ  1 
ATOM   13679 N N   . GLU D 1 681 ? -53.742 -16.238 -4.626  1.00 161.42 ? 756  GLU D N   1 
ATOM   13680 C CA  . GLU D 1 681 ? -53.127 -15.409 -5.656  1.00 161.94 ? 756  GLU D CA  1 
ATOM   13681 C C   . GLU D 1 681 ? -53.374 -13.923 -5.420  1.00 161.54 ? 756  GLU D C   1 
ATOM   13682 O O   . GLU D 1 681 ? -52.517 -13.095 -5.758  1.00 157.40 ? 756  GLU D O   1 
ATOM   13683 C CB  . GLU D 1 681 ? -53.626 -15.839 -7.042  1.00 167.41 ? 756  GLU D CB  1 
ATOM   13684 C CG  . GLU D 1 681 ? -54.981 -15.276 -7.545  1.00 163.99 ? 756  GLU D CG  1 
ATOM   13685 C CD  . GLU D 1 681 ? -56.137 -15.325 -6.540  1.00 166.36 ? 756  GLU D CD  1 
ATOM   13686 O OE1 . GLU D 1 681 ? -57.184 -14.708 -6.827  1.00 169.72 ? 756  GLU D OE1 1 
ATOM   13687 O OE2 . GLU D 1 681 ? -56.036 -16.011 -5.502  1.00 163.07 ? 756  GLU D OE2 1 
ATOM   13688 N N   . ASP D 1 682 ? -54.519 -13.569 -4.828  1.00 158.88 ? 757  ASP D N   1 
ATOM   13689 C CA  . ASP D 1 682 ? -54.818 -12.166 -4.565  1.00 156.16 ? 757  ASP D CA  1 
ATOM   13690 C C   . ASP D 1 682 ? -53.739 -11.517 -3.712  1.00 151.52 ? 757  ASP D C   1 
ATOM   13691 O O   . ASP D 1 682 ? -53.522 -10.303 -3.812  1.00 150.18 ? 757  ASP D O   1 
ATOM   13692 C CB  . ASP D 1 682 ? -56.180 -12.034 -3.885  1.00 160.74 ? 757  ASP D CB  1 
ATOM   13693 C CG  . ASP D 1 682 ? -57.333 -12.274 -4.838  1.00 172.57 ? 757  ASP D CG  1 
ATOM   13694 O OD1 . ASP D 1 682 ? -57.396 -11.598 -5.886  1.00 198.46 ? 757  ASP D OD1 1 
ATOM   13695 O OD2 . ASP D 1 682 ? -58.178 -13.141 -4.538  1.00 162.78 ? 757  ASP D OD2 1 
ATOM   13696 N N   . LEU D 1 683 ? -53.066 -12.307 -2.870  1.00 144.23 ? 758  LEU D N   1 
ATOM   13697 C CA  . LEU D 1 683 ? -51.897 -11.831 -2.138  1.00 137.88 ? 758  LEU D CA  1 
ATOM   13698 C C   . LEU D 1 683 ? -50.978 -11.028 -3.048  1.00 138.64 ? 758  LEU D C   1 
ATOM   13699 O O   . LEU D 1 683 ? -50.700 -9.851  -2.788  1.00 135.83 ? 758  LEU D O   1 
ATOM   13700 C CB  . LEU D 1 683 ? -51.154 -13.020 -1.521  1.00 126.39 ? 758  LEU D CB  1 
ATOM   13701 C CG  . LEU D 1 683 ? -49.942 -12.807 -0.608  1.00 117.47 ? 758  LEU D CG  1 
ATOM   13702 C CD1 . LEU D 1 683 ? -49.904 -13.904 0.439   1.00 104.81 ? 758  LEU D CD1 1 
ATOM   13703 C CD2 . LEU D 1 683 ? -48.641 -12.799 -1.400  1.00 121.86 ? 758  LEU D CD2 1 
ATOM   13704 N N   . LEU D 1 684 ? -50.530 -11.646 -4.147  1.00 142.41 ? 759  LEU D N   1 
ATOM   13705 C CA  . LEU D 1 684 ? -49.677 -10.942 -5.099  1.00 144.37 ? 759  LEU D CA  1 
ATOM   13706 C C   . LEU D 1 684 ? -50.289 -9.605  -5.489  1.00 142.43 ? 759  LEU D C   1 
ATOM   13707 O O   . LEU D 1 684 ? -49.630 -8.560  -5.409  1.00 135.20 ? 759  LEU D O   1 
ATOM   13708 C CB  . LEU D 1 684 ? -49.434 -11.807 -6.337  1.00 152.96 ? 759  LEU D CB  1 
ATOM   13709 C CG  . LEU D 1 684 ? -48.789 -13.173 -6.104  1.00 161.70 ? 759  LEU D CG  1 
ATOM   13710 C CD1 . LEU D 1 684 ? -48.397 -13.809 -7.428  1.00 162.16 ? 759  LEU D CD1 1 
ATOM   13711 C CD2 . LEU D 1 684 ? -47.582 -13.042 -5.190  1.00 163.11 ? 759  LEU D CD2 1 
ATOM   13712 N N   . ARG D 1 685 ? -51.570 -9.618  -5.872  1.00 141.59 ? 760  ARG D N   1 
ATOM   13713 C CA  . ARG D 1 685 ? -52.276 -8.379  -6.175  1.00 136.23 ? 760  ARG D CA  1 
ATOM   13714 C C   . ARG D 1 685 ? -52.097 -7.378  -5.042  1.00 134.76 ? 760  ARG D C   1 
ATOM   13715 O O   . ARG D 1 685 ? -51.557 -6.284  -5.239  1.00 127.58 ? 760  ARG D O   1 
ATOM   13716 C CB  . ARG D 1 685 ? -53.763 -8.657  -6.417  1.00 138.02 ? 760  ARG D CB  1 
ATOM   13717 C CG  . ARG D 1 685 ? -54.062 -9.900  -7.244  1.00 150.47 ? 760  ARG D CG  1 
ATOM   13718 C CD  . ARG D 1 685 ? -53.350 -9.911  -8.587  1.00 161.41 ? 760  ARG D CD  1 
ATOM   13719 N NE  . ARG D 1 685 ? -53.049 -11.277 -8.999  1.00 166.74 ? 760  ARG D NE  1 
ATOM   13720 C CZ  . ARG D 1 685 ? -51.835 -11.728 -9.285  1.00 165.75 ? 760  ARG D CZ  1 
ATOM   13721 N NH1 . ARG D 1 685 ? -50.776 -10.938 -9.242  1.00 157.98 ? 760  ARG D NH1 1 
ATOM   13722 N NH2 . ARG D 1 685 ? -51.681 -13.006 -9.620  1.00 176.51 ? 760  ARG D NH2 1 
ATOM   13723 N N   . LEU D 1 686 ? -52.505 -7.769  -3.830  1.00 140.16 ? 761  LEU D N   1 
ATOM   13724 C CA  . LEU D 1 686 ? -52.303 -6.908  -2.672  1.00 127.20 ? 761  LEU D CA  1 
ATOM   13725 C C   . LEU D 1 686 ? -50.875 -6.387  -2.643  1.00 125.81 ? 761  LEU D C   1 
ATOM   13726 O O   . LEU D 1 686 ? -50.648 -5.170  -2.609  1.00 122.31 ? 761  LEU D O   1 
ATOM   13727 C CB  . LEU D 1 686 ? -52.635 -7.667  -1.385  1.00 124.46 ? 761  LEU D CB  1 
ATOM   13728 C CG  . LEU D 1 686 ? -52.372 -6.910  -0.084  1.00 115.59 ? 761  LEU D CG  1 
ATOM   13729 C CD1 . LEU D 1 686 ? -53.384 -5.790  0.071   1.00 108.23 ? 761  LEU D CD1 1 
ATOM   13730 C CD2 . LEU D 1 686 ? -52.431 -7.851  1.107   1.00 110.00 ? 761  LEU D CD2 1 
ATOM   13731 N N   . LYS D 1 687 ? -49.902 -7.300  -2.750  1.00 127.06 ? 762  LYS D N   1 
ATOM   13732 C CA  . LYS D 1 687 ? -48.497 -6.911  -2.754  1.00 121.34 ? 762  LYS D CA  1 
ATOM   13733 C C   . LYS D 1 687 ? -48.262 -5.771  -3.736  1.00 126.04 ? 762  LYS D C   1 
ATOM   13734 O O   . LYS D 1 687 ? -47.869 -4.666  -3.337  1.00 122.63 ? 762  LYS D O   1 
ATOM   13735 C CB  . LYS D 1 687 ? -47.618 -8.119  -3.089  1.00 111.16 ? 762  LYS D CB  1 
ATOM   13736 C CG  . LYS D 1 687 ? -46.122 -7.860  -2.989  1.00 123.54 ? 762  LYS D CG  1 
ATOM   13737 C CD  . LYS D 1 687 ? -45.331 -9.058  -3.492  1.00 117.77 ? 762  LYS D CD  1 
ATOM   13738 C CE  . LYS D 1 687 ? -43.831 -8.821  -3.419  1.00 125.65 ? 762  LYS D CE  1 
ATOM   13739 N NZ  . LYS D 1 687 ? -43.337 -8.862  -2.016  1.00 124.15 ? 762  LYS D NZ  1 
ATOM   13740 N N   . LYS D 1 688 ? -48.579 -5.997  -5.019  1.00 126.22 ? 763  LYS D N   1 
ATOM   13741 C CA  . LYS D 1 688 ? -48.304 -4.963  -6.011  1.00 123.35 ? 763  LYS D CA  1 
ATOM   13742 C C   . LYS D 1 688 ? -48.999 -3.662  -5.640  1.00 124.89 ? 763  LYS D C   1 
ATOM   13743 O O   . LYS D 1 688 ? -48.364 -2.598  -5.653  1.00 120.11 ? 763  LYS D O   1 
ATOM   13744 C CB  . LYS D 1 688 ? -48.672 -5.440  -7.427  1.00 115.34 ? 763  LYS D CB  1 
ATOM   13745 C CG  . LYS D 1 688 ? -50.145 -5.700  -7.738  1.00 139.42 ? 763  LYS D CG  1 
ATOM   13746 C CD  . LYS D 1 688 ? -50.905 -4.491  -8.271  1.00 152.07 ? 763  LYS D CD  1 
ATOM   13747 C CE  . LYS D 1 688 ? -52.371 -4.846  -8.495  1.00 144.43 ? 763  LYS D CE  1 
ATOM   13748 N NZ  . LYS D 1 688 ? -53.157 -3.708  -9.042  1.00 125.53 ? 763  LYS D NZ  1 
ATOM   13749 N N   . GLN D 1 689 ? -50.265 -3.737  -5.207  1.00 126.17 ? 764  GLN D N   1 
ATOM   13750 C CA  . GLN D 1 689 ? -50.968 -2.526  -4.797  1.00 118.46 ? 764  GLN D CA  1 
ATOM   13751 C C   . GLN D 1 689 ? -50.122 -1.731  -3.816  1.00 120.86 ? 764  GLN D C   1 
ATOM   13752 O O   . GLN D 1 689 ? -49.772 -0.574  -4.080  1.00 125.57 ? 764  GLN D O   1 
ATOM   13753 C CB  . GLN D 1 689 ? -52.329 -2.862  -4.186  1.00 117.64 ? 764  GLN D CB  1 
ATOM   13754 C CG  . GLN D 1 689 ? -53.337 -3.392  -5.187  1.00 124.62 ? 764  GLN D CG  1 
ATOM   13755 C CD  . GLN D 1 689 ? -54.716 -3.583  -4.587  1.00 129.47 ? 764  GLN D CD  1 
ATOM   13756 O OE1 . GLN D 1 689 ? -54.932 -3.350  -3.396  1.00 132.57 ? 764  GLN D OE1 1 
ATOM   13757 N NE2 . GLN D 1 689 ? -55.658 -4.015  -5.413  1.00 122.15 ? 764  GLN D NE2 1 
ATOM   13758 N N   . MET D 1 690 ? -49.710 -2.369  -2.718  1.00 119.16 ? 765  MET D N   1 
ATOM   13759 C CA  . MET D 1 690 ? -48.916 -1.653  -1.728  1.00 115.42 ? 765  MET D CA  1 
ATOM   13760 C C   . MET D 1 690 ? -47.658 -1.083  -2.375  1.00 122.36 ? 765  MET D C   1 
ATOM   13761 O O   . MET D 1 690 ? -47.416 0.130   -2.307  1.00 118.28 ? 765  MET D O   1 
ATOM   13762 C CB  . MET D 1 690 ? -48.603 -2.567  -0.539  1.00 110.72 ? 765  MET D CB  1 
ATOM   13763 C CG  . MET D 1 690 ? -47.386 -2.186  0.295   1.00 108.73 ? 765  MET D CG  1 
ATOM   13764 S SD  . MET D 1 690 ? -45.965 -3.268  0.032   1.00 154.88 ? 765  MET D SD  1 
ATOM   13765 C CE  . MET D 1 690 ? -46.437 -4.722  0.972   1.00 148.35 ? 765  MET D CE  1 
ATOM   13766 N N   . ARG D 1 691 ? -46.909 -1.925  -3.102  1.00 126.32 ? 766  ARG D N   1 
ATOM   13767 C CA  . ARG D 1 691 ? -45.711 -1.455  -3.799  1.00 117.86 ? 766  ARG D CA  1 
ATOM   13768 C C   . ARG D 1 691 ? -45.990 -0.188  -4.590  1.00 118.41 ? 766  ARG D C   1 
ATOM   13769 O O   . ARG D 1 691 ? -45.228 0.783   -4.522  1.00 114.07 ? 766  ARG D O   1 
ATOM   13770 C CB  . ARG D 1 691 ? -45.162 -2.539  -4.730  1.00 114.72 ? 766  ARG D CB  1 
ATOM   13771 C CG  . ARG D 1 691 ? -44.844 -3.865  -4.078  1.00 130.74 ? 766  ARG D CG  1 
ATOM   13772 C CD  . ARG D 1 691 ? -44.025 -3.662  -2.820  1.00 150.60 ? 766  ARG D CD  1 
ATOM   13773 N NE  . ARG D 1 691 ? -44.292 -4.692  -1.824  1.00 180.73 ? 766  ARG D NE  1 
ATOM   13774 C CZ  . ARG D 1 691 ? -43.374 -5.512  -1.334  1.00 180.71 ? 766  ARG D CZ  1 
ATOM   13775 N NH1 . ARG D 1 691 ? -42.117 -5.460  -1.738  1.00 166.82 ? 766  ARG D NH1 1 
ATOM   13776 N NH2 . ARG D 1 691 ? -43.729 -6.410  -0.420  1.00 176.92 ? 766  ARG D NH2 1 
ATOM   13777 N N   . VAL D 1 692 ? -47.093 -0.171  -5.338  1.00 116.55 ? 767  VAL D N   1 
ATOM   13778 C CA  . VAL D 1 692 ? -47.390 0.998   -6.153  1.00 109.23 ? 767  VAL D CA  1 
ATOM   13779 C C   . VAL D 1 692 ? -47.872 2.139   -5.271  1.00 112.09 ? 767  VAL D C   1 
ATOM   13780 O O   . VAL D 1 692 ? -47.374 3.269   -5.361  1.00 106.34 ? 767  VAL D O   1 
ATOM   13781 C CB  . VAL D 1 692 ? -48.417 0.643   -7.242  1.00 103.98 ? 767  VAL D CB  1 
ATOM   13782 C CG1 . VAL D 1 692 ? -48.888 1.897   -7.961  1.00 115.94 ? 767  VAL D CG1 1 
ATOM   13783 C CG2 . VAL D 1 692 ? -47.818 -0.354  -8.222  1.00 115.86 ? 767  VAL D CG2 1 
ATOM   13784 N N   . PHE D 1 693 ? -48.800 1.837   -4.357  1.00 126.98 ? 768  PHE D N   1 
ATOM   13785 C CA  . PHE D 1 693 ? -49.556 2.890   -3.689  1.00 126.06 ? 768  PHE D CA  1 
ATOM   13786 C C   . PHE D 1 693 ? -48.621 3.865   -2.990  1.00 125.71 ? 768  PHE D C   1 
ATOM   13787 O O   . PHE D 1 693 ? -48.576 5.054   -3.325  1.00 124.68 ? 768  PHE D O   1 
ATOM   13788 C CB  . PHE D 1 693 ? -50.548 2.285   -2.695  1.00 105.91 ? 768  PHE D CB  1 
ATOM   13789 C CG  . PHE D 1 693 ? -51.022 3.252   -1.648  1.00 97.21  ? 768  PHE D CG  1 
ATOM   13790 C CD1 . PHE D 1 693 ? -51.697 4.406   -2.012  1.00 99.43  ? 768  PHE D CD1 1 
ATOM   13791 C CD2 . PHE D 1 693 ? -50.799 3.009   -0.304  1.00 103.98 ? 768  PHE D CD2 1 
ATOM   13792 C CE1 . PHE D 1 693 ? -52.137 5.301   -1.058  1.00 99.61  ? 768  PHE D CE1 1 
ATOM   13793 C CE2 . PHE D 1 693 ? -51.239 3.899   0.655   1.00 111.17 ? 768  PHE D CE2 1 
ATOM   13794 C CZ  . PHE D 1 693 ? -51.909 5.046   0.277   1.00 105.74 ? 768  PHE D CZ  1 
ATOM   13795 N N   . CYS D 1 694 ? -47.834 3.372   -2.041  1.00 129.42 ? 769  CYS D N   1 
ATOM   13796 C CA  . CYS D 1 694 ? -46.966 4.303   -1.348  1.00 147.81 ? 769  CYS D CA  1 
ATOM   13797 C C   . CYS D 1 694 ? -45.694 4.637   -2.107  1.00 136.20 ? 769  CYS D C   1 
ATOM   13798 O O   . CYS D 1 694 ? -44.955 5.520   -1.656  1.00 136.97 ? 769  CYS D O   1 
ATOM   13799 C CB  . CYS D 1 694 ? -46.642 3.813   0.059   1.00 190.29 ? 769  CYS D CB  1 
ATOM   13800 S SG  . CYS D 1 694 ? -47.642 4.738   1.242   1.00 338.41 ? 769  CYS D SG  1 
ATOM   13801 N N   . GLN D 1 695 ? -45.427 4.000   -3.249  1.00 131.81 ? 770  GLN D N   1 
ATOM   13802 C CA  . GLN D 1 695 ? -44.503 4.635   -4.178  1.00 129.70 ? 770  GLN D CA  1 
ATOM   13803 C C   . GLN D 1 695 ? -45.000 6.040   -4.476  1.00 124.15 ? 770  GLN D C   1 
ATOM   13804 O O   . GLN D 1 695 ? -44.255 7.022   -4.359  1.00 120.35 ? 770  GLN D O   1 
ATOM   13805 C CB  . GLN D 1 695 ? -44.359 3.812   -5.460  1.00 120.82 ? 770  GLN D CB  1 
ATOM   13806 C CG  . GLN D 1 695 ? -43.307 4.351   -6.425  1.00 127.43 ? 770  GLN D CG  1 
ATOM   13807 C CD  . GLN D 1 695 ? -41.918 4.411   -5.815  1.00 133.28 ? 770  GLN D CD  1 
ATOM   13808 O OE1 . GLN D 1 695 ? -41.334 3.384   -5.468  1.00 139.69 ? 770  GLN D OE1 1 
ATOM   13809 N NE2 . GLN D 1 695 ? -41.379 5.618   -5.689  1.00 132.38 ? 770  GLN D NE2 1 
ATOM   13810 N N   . ILE D 1 696 ? -46.293 6.154   -4.791  1.00 113.67 ? 771  ILE D N   1 
ATOM   13811 C CA  . ILE D 1 696 ? -46.917 7.463   -4.921  1.00 112.02 ? 771  ILE D CA  1 
ATOM   13812 C C   . ILE D 1 696 ? -46.744 8.264   -3.637  1.00 121.28 ? 771  ILE D C   1 
ATOM   13813 O O   . ILE D 1 696 ? -46.467 9.469   -3.683  1.00 117.28 ? 771  ILE D O   1 
ATOM   13814 C CB  . ILE D 1 696 ? -48.398 7.311   -5.312  1.00 102.50 ? 771  ILE D CB  1 
ATOM   13815 C CG1 . ILE D 1 696 ? -48.566 6.159   -6.299  1.00 101.22 ? 771  ILE D CG1 1 
ATOM   13816 C CG2 . ILE D 1 696 ? -48.903 8.585   -5.953  1.00 108.91 ? 771  ILE D CG2 1 
ATOM   13817 C CD1 . ILE D 1 696 ? -50.003 5.833   -6.613  1.00 98.21  ? 771  ILE D CD1 1 
ATOM   13818 N N   . CYS D 1 697 ? -46.871 7.609   -2.473  1.00 135.10 ? 772  CYS D N   1 
ATOM   13819 C CA  . CYS D 1 697 ? -46.612 8.303   -1.213  1.00 134.17 ? 772  CYS D CA  1 
ATOM   13820 C C   . CYS D 1 697 ? -45.271 9.013   -1.272  1.00 123.60 ? 772  CYS D C   1 
ATOM   13821 O O   . CYS D 1 697 ? -45.179 10.218  -1.005  1.00 124.15 ? 772  CYS D O   1 
ATOM   13822 C CB  . CYS D 1 697 ? -46.633 7.332   -0.030  1.00 131.96 ? 772  CYS D CB  1 
ATOM   13823 S SG  . CYS D 1 697 ? -48.179 6.407   0.206   1.00 136.11 ? 772  CYS D SG  1 
ATOM   13824 N N   . GLN D 1 698 ? -44.225 8.283   -1.677  1.00 115.97 ? 773  GLN D N   1 
ATOM   13825 C CA  . GLN D 1 698 ? -42.900 8.884   -1.775  1.00 112.64 ? 773  GLN D CA  1 
ATOM   13826 C C   . GLN D 1 698 ? -42.920 10.103  -2.680  1.00 114.83 ? 773  GLN D C   1 
ATOM   13827 O O   . GLN D 1 698 ? -42.381 11.157  -2.321  1.00 115.26 ? 773  GLN D O   1 
ATOM   13828 C CB  . GLN D 1 698 ? -41.888 7.855   -2.278  1.00 107.48 ? 773  GLN D CB  1 
ATOM   13829 C CG  . GLN D 1 698 ? -41.743 6.650   -1.362  1.00 119.63 ? 773  GLN D CG  1 
ATOM   13830 C CD  . GLN D 1 698 ? -40.825 5.588   -1.930  1.00 117.33 ? 773  GLN D CD  1 
ATOM   13831 O OE1 . GLN D 1 698 ? -41.257 4.476   -2.235  1.00 118.92 ? 773  GLN D OE1 1 
ATOM   13832 N NE2 . GLN D 1 698 ? -39.547 5.922   -2.067  1.00 103.71 ? 773  GLN D NE2 1 
ATOM   13833 N N   . HIS D 1 699 ? -43.569 9.991   -3.843  1.00 116.85 ? 774  HIS D N   1 
ATOM   13834 C CA  . HIS D 1 699 ? -43.725 11.152  -4.710  1.00 119.97 ? 774  HIS D CA  1 
ATOM   13835 C C   . HIS D 1 699 ? -44.346 12.304  -3.936  1.00 110.33 ? 774  HIS D C   1 
ATOM   13836 O O   . HIS D 1 699 ? -43.790 13.407  -3.877  1.00 101.74 ? 774  HIS D O   1 
ATOM   13837 C CB  . HIS D 1 699 ? -44.588 10.801  -5.923  1.00 132.24 ? 774  HIS D CB  1 
ATOM   13838 C CG  . HIS D 1 699 ? -44.089 9.632   -6.713  1.00 147.47 ? 774  HIS D CG  1 
ATOM   13839 N ND1 . HIS D 1 699 ? -42.852 9.060   -6.503  1.00 154.37 ? 774  HIS D ND1 1 
ATOM   13840 C CD2 . HIS D 1 699 ? -44.665 8.925   -7.714  1.00 153.04 ? 774  HIS D CD2 1 
ATOM   13841 C CE1 . HIS D 1 699 ? -42.688 8.052   -7.341  1.00 143.66 ? 774  HIS D CE1 1 
ATOM   13842 N NE2 . HIS D 1 699 ? -43.773 7.949   -8.086  1.00 145.04 ? 774  HIS D NE2 1 
ATOM   13843 N N   . TYR D 1 700 ? -45.483 12.043  -3.290  1.00 116.32 ? 775  TYR D N   1 
ATOM   13844 C CA  . TYR D 1 700 ? -46.173 13.089  -2.556  1.00 115.52 ? 775  TYR D CA  1 
ATOM   13845 C C   . TYR D 1 700 ? -45.425 13.491  -1.295  1.00 112.09 ? 775  TYR D C   1 
ATOM   13846 O O   . TYR D 1 700 ? -45.769 14.512  -0.690  1.00 109.58 ? 775  TYR D O   1 
ATOM   13847 C CB  . TYR D 1 700 ? -47.591 12.631  -2.221  1.00 107.54 ? 775  TYR D CB  1 
ATOM   13848 C CG  . TYR D 1 700 ? -48.520 12.708  -3.410  1.00 113.25 ? 775  TYR D CG  1 
ATOM   13849 C CD1 . TYR D 1 700 ? -48.672 13.889  -4.126  1.00 118.22 ? 775  TYR D CD1 1 
ATOM   13850 C CD2 . TYR D 1 700 ? -49.233 11.594  -3.827  1.00 113.13 ? 775  TYR D CD2 1 
ATOM   13851 C CE1 . TYR D 1 700 ? -49.516 13.957  -5.222  1.00 119.13 ? 775  TYR D CE1 1 
ATOM   13852 C CE2 . TYR D 1 700 ? -50.079 11.653  -4.916  1.00 115.56 ? 775  TYR D CE2 1 
ATOM   13853 C CZ  . TYR D 1 700 ? -50.216 12.834  -5.611  1.00 117.82 ? 775  TYR D CZ  1 
ATOM   13854 O OH  . TYR D 1 700 ? -51.060 12.886  -6.696  1.00 120.96 ? 775  TYR D OH  1 
ATOM   13855 N N   . LEU D 1 701 ? -44.413 12.719  -0.887  1.00 109.89 ? 776  LEU D N   1 
ATOM   13856 C CA  . LEU D 1 701 ? -43.529 13.177  0.177   1.00 104.75 ? 776  LEU D CA  1 
ATOM   13857 C C   . LEU D 1 701 ? -42.728 14.394  -0.263  1.00 114.38 ? 776  LEU D C   1 
ATOM   13858 O O   . LEU D 1 701 ? -42.438 15.274  0.556   1.00 102.58 ? 776  LEU D O   1 
ATOM   13859 C CB  . LEU D 1 701 ? -42.588 12.053  0.610   1.00 100.95 ? 776  LEU D CB  1 
ATOM   13860 C CG  . LEU D 1 701 ? -42.796 11.468  2.007   1.00 109.36 ? 776  LEU D CG  1 
ATOM   13861 C CD1 . LEU D 1 701 ? -41.924 10.240  2.194   1.00 92.79  ? 776  LEU D CD1 1 
ATOM   13862 C CD2 . LEU D 1 701 ? -42.505 12.502  3.086   1.00 114.54 ? 776  LEU D CD2 1 
ATOM   13863 N N   . THR D 1 702 ? -42.372 14.465  -1.543  1.00 119.57 ? 777  THR D N   1 
ATOM   13864 C CA  . THR D 1 702 ? -41.632 15.595  -2.084  1.00 107.62 ? 777  THR D CA  1 
ATOM   13865 C C   . THR D 1 702 ? -42.546 16.656  -2.681  1.00 110.53 ? 777  THR D C   1 
ATOM   13866 O O   . THR D 1 702 ? -42.055 17.598  -3.311  1.00 111.58 ? 777  THR D O   1 
ATOM   13867 C CB  . THR D 1 702 ? -40.629 15.111  -3.135  1.00 89.98  ? 777  THR D CB  1 
ATOM   13868 O OG1 . THR D 1 702 ? -41.335 14.580  -4.263  1.00 91.59  ? 777  THR D OG1 1 
ATOM   13869 C CG2 . THR D 1 702 ? -39.738 14.030  -2.548  1.00 88.93  ? 777  THR D CG2 1 
ATOM   13870 N N   . ASN D 1 703 ? -43.856 16.524  -2.490  1.00 110.57 ? 778  ASN D N   1 
ATOM   13871 C CA  . ASN D 1 703 ? -44.798 17.513  -2.992  1.00 105.82 ? 778  ASN D CA  1 
ATOM   13872 C C   . ASN D 1 703 ? -44.529 18.872  -2.355  1.00 106.24 ? 778  ASN D C   1 
ATOM   13873 O O   . ASN D 1 703 ? -43.957 18.969  -1.267  1.00 111.26 ? 778  ASN D O   1 
ATOM   13874 C CB  . ASN D 1 703 ? -46.229 17.060  -2.702  1.00 97.07  ? 778  ASN D CB  1 
ATOM   13875 C CG  . ASN D 1 703 ? -47.263 17.931  -3.375  1.00 107.18 ? 778  ASN D CG  1 
ATOM   13876 O OD1 . ASN D 1 703 ? -47.437 19.098  -3.024  1.00 103.33 ? 778  ASN D OD1 1 
ATOM   13877 N ND2 . ASN D 1 703 ? -47.961 17.365  -4.351  1.00 111.57 ? 778  ASN D ND2 1 
ATOM   13878 N N   . VAL D 1 704 ? -44.941 19.933  -3.049  1.00 105.78 ? 779  VAL D N   1 
ATOM   13879 C CA  . VAL D 1 704 ? -44.687 21.280  -2.549  1.00 104.32 ? 779  VAL D CA  1 
ATOM   13880 C C   . VAL D 1 704 ? -45.603 21.598  -1.371  1.00 109.89 ? 779  VAL D C   1 
ATOM   13881 O O   . VAL D 1 704 ? -45.194 22.263  -0.411  1.00 121.57 ? 779  VAL D O   1 
ATOM   13882 C CB  . VAL D 1 704 ? -44.829 22.308  -3.688  1.00 105.08 ? 779  VAL D CB  1 
ATOM   13883 C CG1 . VAL D 1 704 ? -46.095 22.049  -4.492  1.00 100.22 ? 779  VAL D CG1 1 
ATOM   13884 C CG2 . VAL D 1 704 ? -44.809 23.732  -3.143  1.00 96.16  ? 779  VAL D CG2 1 
ATOM   13885 N N   . ASN D 1 705 ? -46.844 21.117  -1.414  1.00 101.66 ? 780  ASN D N   1 
ATOM   13886 C CA  . ASN D 1 705 ? -47.778 21.349  -0.320  1.00 108.52 ? 780  ASN D CA  1 
ATOM   13887 C C   . ASN D 1 705 ? -47.385 20.523  0.899   1.00 109.24 ? 780  ASN D C   1 
ATOM   13888 O O   . ASN D 1 705 ? -47.242 19.301  0.812   1.00 102.16 ? 780  ASN D O   1 
ATOM   13889 C CB  . ASN D 1 705 ? -49.201 21.004  -0.754  1.00 108.47 ? 780  ASN D CB  1 
ATOM   13890 C CG  . ASN D 1 705 ? -50.249 21.622  0.148   1.00 113.90 ? 780  ASN D CG  1 
ATOM   13891 O OD1 . ASN D 1 705 ? -50.274 21.372  1.354   1.00 108.38 ? 780  ASN D OD1 1 
ATOM   13892 N ND2 . ASN D 1 705 ? -51.117 22.441  -0.431  1.00 114.97 ? 780  ASN D ND2 1 
ATOM   13893 N N   . THR D 1 706 ? -47.229 21.195  2.043   1.00 110.35 ? 781  THR D N   1 
ATOM   13894 C CA  . THR D 1 706 ? -46.788 20.504  3.251   1.00 99.08  ? 781  THR D CA  1 
ATOM   13895 C C   . THR D 1 706 ? -47.834 19.513  3.747   1.00 102.21 ? 781  THR D C   1 
ATOM   13896 O O   . THR D 1 706 ? -47.483 18.458  4.283   1.00 97.88  ? 781  THR D O   1 
ATOM   13897 C CB  . THR D 1 706 ? -46.454 21.514  4.348   1.00 83.53  ? 781  THR D CB  1 
ATOM   13898 O OG1 . THR D 1 706 ? -47.644 22.210  4.739   1.00 90.05  ? 781  THR D OG1 1 
ATOM   13899 C CG2 . THR D 1 706 ? -45.420 22.514  3.855   1.00 89.94  ? 781  THR D CG2 1 
ATOM   13900 N N   . THR D 1 707 ? -49.121 19.833  3.586   1.00 100.39 ? 782  THR D N   1 
ATOM   13901 C CA  . THR D 1 707 ? -50.165 18.934  4.069   1.00 93.97  ? 782  THR D CA  1 
ATOM   13902 C C   . THR D 1 707 ? -50.166 17.622  3.292   1.00 95.95  ? 782  THR D C   1 
ATOM   13903 O O   . THR D 1 707 ? -50.393 16.549  3.867   1.00 101.65 ? 782  THR D O   1 
ATOM   13904 C CB  . THR D 1 707 ? -51.530 19.616  3.981   1.00 82.98  ? 782  THR D CB  1 
ATOM   13905 O OG1 . THR D 1 707 ? -51.929 19.718  2.609   1.00 111.89 ? 782  THR D OG1 1 
ATOM   13906 C CG2 . THR D 1 707 ? -51.464 21.010  4.590   1.00 84.88  ? 782  THR D CG2 1 
ATOM   13907 N N   . VAL D 1 708 ? -49.902 17.687  1.986   1.00 98.51  ? 783  VAL D N   1 
ATOM   13908 C CA  . VAL D 1 708 ? -49.813 16.472  1.185   1.00 98.40  ? 783  VAL D CA  1 
ATOM   13909 C C   . VAL D 1 708 ? -48.632 15.622  1.638   1.00 97.04  ? 783  VAL D C   1 
ATOM   13910 O O   . VAL D 1 708 ? -48.750 14.397  1.791   1.00 100.18 ? 783  VAL D O   1 
ATOM   13911 C CB  . VAL D 1 708 ? -49.726 16.832  -0.309  1.00 94.77  ? 783  VAL D CB  1 
ATOM   13912 C CG1 . VAL D 1 708 ? -49.485 15.591  -1.148  1.00 93.49  ? 783  VAL D CG1 1 
ATOM   13913 C CG2 . VAL D 1 708 ? -50.994 17.551  -0.754  1.00 96.81  ? 783  VAL D CG2 1 
ATOM   13914 N N   . LYS D 1 709 ? -47.477 16.259  1.862   1.00 91.67  ? 784  LYS D N   1 
ATOM   13915 C CA  . LYS D 1 709 ? -46.324 15.548  2.406   1.00 104.66 ? 784  LYS D CA  1 
ATOM   13916 C C   . LYS D 1 709 ? -46.654 14.901  3.743   1.00 101.06 ? 784  LYS D C   1 
ATOM   13917 O O   . LYS D 1 709 ? -46.250 13.765  4.005   1.00 93.97  ? 784  LYS D O   1 
ATOM   13918 C CB  . LYS D 1 709 ? -45.139 16.500  2.575   1.00 106.24 ? 784  LYS D CB  1 
ATOM   13919 C CG  . LYS D 1 709 ? -44.849 17.403  1.398   1.00 106.23 ? 784  LYS D CG  1 
ATOM   13920 C CD  . LYS D 1 709 ? -44.000 18.580  1.849   1.00 101.82 ? 784  LYS D CD  1 
ATOM   13921 C CE  . LYS D 1 709 ? -42.534 18.198  1.971   1.00 102.95 ? 784  LYS D CE  1 
ATOM   13922 N NZ  . LYS D 1 709 ? -41.677 19.387  2.241   1.00 115.14 ? 784  LYS D NZ  1 
ATOM   13923 N N   . GLU D 1 710 ? -47.378 15.617  4.606   1.00 96.41  ? 785  GLU D N   1 
ATOM   13924 C CA  . GLU D 1 710 ? -47.698 15.093  5.929   1.00 89.08  ? 785  GLU D CA  1 
ATOM   13925 C C   . GLU D 1 710 ? -48.607 13.877  5.832   1.00 96.04  ? 785  GLU D C   1 
ATOM   13926 O O   . GLU D 1 710 ? -48.394 12.875  6.526   1.00 103.55 ? 785  GLU D O   1 
ATOM   13927 C CB  . GLU D 1 710 ? -48.348 16.187  6.777   1.00 84.24  ? 785  GLU D CB  1 
ATOM   13928 C CG  . GLU D 1 710 ? -47.392 17.291  7.199   1.00 89.11  ? 785  GLU D CG  1 
ATOM   13929 C CD  . GLU D 1 710 ? -48.109 18.506  7.752   1.00 103.77 ? 785  GLU D CD  1 
ATOM   13930 O OE1 . GLU D 1 710 ? -49.340 18.433  7.946   1.00 114.52 ? 785  GLU D OE1 1 
ATOM   13931 O OE2 . GLU D 1 710 ? -47.441 19.536  7.986   1.00 103.29 ? 785  GLU D OE2 1 
ATOM   13932 N N   . GLN D 1 711 ? -49.624 13.944  4.971   1.00 85.86  ? 786  GLN D N   1 
ATOM   13933 C CA  . GLN D 1 711 ? -50.513 12.801  4.792   1.00 83.52  ? 786  GLN D CA  1 
ATOM   13934 C C   . GLN D 1 711 ? -49.751 11.599  4.241   1.00 88.58  ? 786  GLN D C   1 
ATOM   13935 O O   . GLN D 1 711 ? -49.912 10.466  4.721   1.00 95.97  ? 786  GLN D O   1 
ATOM   13936 C CB  . GLN D 1 711 ? -51.672 13.177  3.869   1.00 71.06  ? 786  GLN D CB  1 
ATOM   13937 C CG  . GLN D 1 711 ? -52.746 12.110  3.789   1.00 74.12  ? 786  GLN D CG  1 
ATOM   13938 C CD  . GLN D 1 711 ? -53.422 11.883  5.122   1.00 76.02  ? 786  GLN D CD  1 
ATOM   13939 O OE1 . GLN D 1 711 ? -54.092 12.771  5.650   1.00 77.91  ? 786  GLN D OE1 1 
ATOM   13940 N NE2 . GLN D 1 711 ? -53.239 10.693  5.682   1.00 82.43  ? 786  GLN D NE2 1 
ATOM   13941 N N   . ALA D 1 712 ? -48.912 11.833  3.226   1.00 86.44  ? 787  ALA D N   1 
ATOM   13942 C CA  . ALA D 1 712 ? -48.136 10.747  2.639   1.00 93.79  ? 787  ALA D CA  1 
ATOM   13943 C C   . ALA D 1 712 ? -47.186 10.134  3.658   1.00 92.15  ? 787  ALA D C   1 
ATOM   13944 O O   . ALA D 1 712 ? -47.060 8.910   3.737   1.00 90.44  ? 787  ALA D O   1 
ATOM   13945 C CB  . ALA D 1 712 ? -47.363 11.253  1.421   1.00 102.90 ? 787  ALA D CB  1 
ATOM   13946 N N   . PHE D 1 713 ? -46.526 10.972  4.460   1.00 94.44  ? 788  PHE D N   1 
ATOM   13947 C CA  . PHE D 1 713 ? -45.595 10.490  5.476   1.00 93.56  ? 788  PHE D CA  1 
ATOM   13948 C C   . PHE D 1 713 ? -46.312 9.671   6.543   1.00 85.81  ? 788  PHE D C   1 
ATOM   13949 O O   . PHE D 1 713 ? -45.835 8.606   6.953   1.00 77.41  ? 788  PHE D O   1 
ATOM   13950 C CB  . PHE D 1 713 ? -44.875 11.689  6.098   1.00 90.16  ? 788  PHE D CB  1 
ATOM   13951 C CG  . PHE D 1 713 ? -43.950 11.334  7.222   1.00 94.02  ? 788  PHE D CG  1 
ATOM   13952 C CD1 . PHE D 1 713 ? -42.726 10.741  6.972   1.00 91.67  ? 788  PHE D CD1 1 
ATOM   13953 C CD2 . PHE D 1 713 ? -44.303 11.607  8.533   1.00 90.80  ? 788  PHE D CD2 1 
ATOM   13954 C CE1 . PHE D 1 713 ? -41.874 10.421  8.008   1.00 91.09  ? 788  PHE D CE1 1 
ATOM   13955 C CE2 . PHE D 1 713 ? -43.456 11.290  9.572   1.00 86.65  ? 788  PHE D CE2 1 
ATOM   13956 C CZ  . PHE D 1 713 ? -42.240 10.695  9.310   1.00 91.17  ? 788  PHE D CZ  1 
ATOM   13957 N N   . THR D 1 714 ? -47.459 10.166  7.012   1.00 80.23  ? 789  THR D N   1 
ATOM   13958 C CA  . THR D 1 714 ? -48.257 9.445   7.997   1.00 73.87  ? 789  THR D CA  1 
ATOM   13959 C C   . THR D 1 714 ? -48.641 8.060   7.485   1.00 81.91  ? 789  THR D C   1 
ATOM   13960 O O   . THR D 1 714 ? -48.339 7.032   8.116   1.00 85.72  ? 789  THR D O   1 
ATOM   13961 C CB  . THR D 1 714 ? -49.505 10.269  8.326   1.00 79.31  ? 789  THR D CB  1 
ATOM   13962 O OG1 . THR D 1 714 ? -49.124 11.477  9.001   1.00 85.87  ? 789  THR D OG1 1 
ATOM   13963 C CG2 . THR D 1 714 ? -50.471 9.482   9.188   1.00 93.16  ? 789  THR D CG2 1 
ATOM   13964 N N   . ILE D 1 715 ? -49.310 8.022   6.328   1.00 79.26  ? 790  ILE D N   1 
ATOM   13965 C CA  . ILE D 1 715 ? -49.735 6.751   5.751   1.00 87.26  ? 790  ILE D CA  1 
ATOM   13966 C C   . ILE D 1 715 ? -48.536 5.860   5.461   1.00 89.29  ? 790  ILE D C   1 
ATOM   13967 O O   . ILE D 1 715 ? -48.613 4.638   5.614   1.00 86.06  ? 790  ILE D O   1 
ATOM   13968 C CB  . ILE D 1 715 ? -50.578 7.003   4.486   1.00 84.41  ? 790  ILE D CB  1 
ATOM   13969 C CG1 . ILE D 1 715 ? -51.943 7.578   4.860   1.00 71.84  ? 790  ILE D CG1 1 
ATOM   13970 C CG2 . ILE D 1 715 ? -50.761 5.722   3.690   1.00 75.45  ? 790  ILE D CG2 1 
ATOM   13971 C CD1 . ILE D 1 715 ? -52.741 8.056   3.674   1.00 78.31  ? 790  ILE D CD1 1 
ATOM   13972 N N   . LEU D 1 716 ? -47.401 6.453   5.083   1.00 93.35  ? 791  LEU D N   1 
ATOM   13973 C CA  . LEU D 1 716 ? -46.220 5.672   4.736   1.00 94.01  ? 791  LEU D CA  1 
ATOM   13974 C C   . LEU D 1 716 ? -45.623 4.989   5.956   1.00 87.62  ? 791  LEU D C   1 
ATOM   13975 O O   . LEU D 1 716 ? -45.246 3.815   5.891   1.00 81.76  ? 791  LEU D O   1 
ATOM   13976 C CB  . LEU D 1 716 ? -45.191 6.578   4.064   1.00 90.22  ? 791  LEU D CB  1 
ATOM   13977 C CG  . LEU D 1 716 ? -43.990 5.952   3.361   1.00 96.16  ? 791  LEU D CG  1 
ATOM   13978 C CD1 . LEU D 1 716 ? -44.353 4.640   2.688   1.00 95.64  ? 791  LEU D CD1 1 
ATOM   13979 C CD2 . LEU D 1 716 ? -43.452 6.937   2.343   1.00 93.48  ? 791  LEU D CD2 1 
ATOM   13980 N N   . CYS D 1 717 ? -45.522 5.707   7.075   1.00 84.09  ? 792  CYS D N   1 
ATOM   13981 C CA  . CYS D 1 717 ? -45.032 5.080   8.298   1.00 75.83  ? 792  CYS D CA  1 
ATOM   13982 C C   . CYS D 1 717 ? -45.973 3.975   8.763   1.00 82.20  ? 792  CYS D C   1 
ATOM   13983 O O   . CYS D 1 717 ? -45.524 2.877   9.126   1.00 93.79  ? 792  CYS D O   1 
ATOM   13984 C CB  . CYS D 1 717 ? -44.845 6.128   9.392   1.00 73.71  ? 792  CYS D CB  1 
ATOM   13985 S SG  . CYS D 1 717 ? -43.629 7.404   8.994   1.00 90.90  ? 792  CYS D SG  1 
ATOM   13986 N N   . ASP D 1 718 ? -47.285 4.238   8.747   1.00 82.15  ? 793  ASP D N   1 
ATOM   13987 C CA  . ASP D 1 718 ? -48.225 3.187   9.138   1.00 82.01  ? 793  ASP D CA  1 
ATOM   13988 C C   . ASP D 1 718 ? -48.127 1.977   8.212   1.00 79.69  ? 793  ASP D C   1 
ATOM   13989 O O   . ASP D 1 718 ? -48.193 0.830   8.669   1.00 73.41  ? 793  ASP D O   1 
ATOM   13990 C CB  . ASP D 1 718 ? -49.653 3.731   9.177   1.00 79.00  ? 793  ASP D CB  1 
ATOM   13991 C CG  . ASP D 1 718 ? -49.884 4.662   10.349  1.00 81.92  ? 793  ASP D CG  1 
ATOM   13992 O OD1 . ASP D 1 718 ? -48.934 4.867   11.134  1.00 73.58  ? 793  ASP D OD1 1 
ATOM   13993 O OD2 . ASP D 1 718 ? -51.012 5.180   10.493  1.00 76.88  ? 793  ASP D OD2 1 
ATOM   13994 N N   . ILE D 1 719 ? -47.943 2.213   6.912   1.00 82.92  ? 794  ILE D N   1 
ATOM   13995 C CA  . ILE D 1 719 ? -47.831 1.118   5.951   1.00 81.78  ? 794  ILE D CA  1 
ATOM   13996 C C   . ILE D 1 719 ? -46.570 0.308   6.221   1.00 84.80  ? 794  ILE D C   1 
ATOM   13997 O O   . ILE D 1 719 ? -46.595 -0.929  6.248   1.00 78.67  ? 794  ILE D O   1 
ATOM   13998 C CB  . ILE D 1 719 ? -47.845 1.672   4.514   1.00 80.76  ? 794  ILE D CB  1 
ATOM   13999 C CG1 . ILE D 1 719 ? -49.279 1.907   4.036   1.00 79.50  ? 794  ILE D CG1 1 
ATOM   14000 C CG2 . ILE D 1 719 ? -47.112 0.734   3.565   1.00 94.63  ? 794  ILE D CG2 1 
ATOM   14001 C CD1 . ILE D 1 719 ? -50.003 0.651   3.618   1.00 91.75  ? 794  ILE D CD1 1 
ATOM   14002 N N   . LEU D 1 720 ? -45.445 1.003   6.415   1.00 83.14  ? 795  LEU D N   1 
ATOM   14003 C CA  . LEU D 1 720 ? -44.187 0.335   6.720   1.00 86.90  ? 795  LEU D CA  1 
ATOM   14004 C C   . LEU D 1 720 ? -44.322 -0.556  7.944   1.00 80.39  ? 795  LEU D C   1 
ATOM   14005 O O   . LEU D 1 720 ? -43.838 -1.693  7.949   1.00 75.14  ? 795  LEU D O   1 
ATOM   14006 C CB  . LEU D 1 720 ? -43.084 1.369   6.937   1.00 72.98  ? 795  LEU D CB  1 
ATOM   14007 C CG  . LEU D 1 720 ? -42.524 2.075   5.703   1.00 74.57  ? 795  LEU D CG  1 
ATOM   14008 C CD1 . LEU D 1 720 ? -41.214 2.756   6.045   1.00 83.66  ? 795  LEU D CD1 1 
ATOM   14009 C CD2 . LEU D 1 720 ? -42.335 1.095   4.555   1.00 74.73  ? 795  LEU D CD2 1 
ATOM   14010 N N   . MET D 1 721 ? -44.989 -0.063  8.988   1.00 82.74  ? 796  MET D N   1 
ATOM   14011 C CA  . MET D 1 721 ? -45.125 -0.874  10.192  1.00 82.24  ? 796  MET D CA  1 
ATOM   14012 C C   . MET D 1 721 ? -46.056 -2.058  9.952   1.00 89.11  ? 796  MET D C   1 
ATOM   14013 O O   . MET D 1 721 ? -45.742 -3.192  10.332  1.00 90.18  ? 796  MET D O   1 
ATOM   14014 C CB  . MET D 1 721 ? -45.614 -0.018  11.357  1.00 61.32  ? 796  MET D CB  1 
ATOM   14015 C CG  . MET D 1 721 ? -45.633 -0.758  12.679  1.00 83.47  ? 796  MET D CG  1 
ATOM   14016 S SD  . MET D 1 721 ? -43.966 -1.297  13.109  1.00 83.89  ? 796  MET D SD  1 
ATOM   14017 C CE  . MET D 1 721 ? -43.213 0.266   13.550  1.00 76.12  ? 796  MET D CE  1 
ATOM   14018 N N   . ILE D 1 722 ? -47.196 -1.819  9.297   1.00 85.89  ? 797  ILE D N   1 
ATOM   14019 C CA  . ILE D 1 722 ? -48.169 -2.886  9.070   1.00 84.22  ? 797  ILE D CA  1 
ATOM   14020 C C   . ILE D 1 722 ? -47.599 -3.960  8.153   1.00 87.52  ? 797  ILE D C   1 
ATOM   14021 O O   . ILE D 1 722 ? -47.925 -5.146  8.290   1.00 86.14  ? 797  ILE D O   1 
ATOM   14022 C CB  . ILE D 1 722 ? -49.476 -2.294  8.505   1.00 86.75  ? 797  ILE D CB  1 
ATOM   14023 C CG1 . ILE D 1 722 ? -50.152 -1.408  9.548   1.00 82.10  ? 797  ILE D CG1 1 
ATOM   14024 C CG2 . ILE D 1 722 ? -50.429 -3.393  8.070   1.00 78.31  ? 797  ILE D CG2 1 
ATOM   14025 C CD1 . ILE D 1 722 ? -51.243 -0.540  8.979   1.00 80.19  ? 797  ILE D CD1 1 
ATOM   14026 N N   . PHE D 1 723 ? -46.746 -3.575  7.207   1.00 84.52  ? 798  PHE D N   1 
ATOM   14027 C CA  . PHE D 1 723 ? -46.141 -4.520  6.280   1.00 88.61  ? 798  PHE D CA  1 
ATOM   14028 C C   . PHE D 1 723 ? -44.663 -4.747  6.582   1.00 97.25  ? 798  PHE D C   1 
ATOM   14029 O O   . PHE D 1 723 ? -43.875 -5.039  5.680   1.00 110.79 ? 798  PHE D O   1 
ATOM   14030 C CB  . PHE D 1 723 ? -46.333 -4.052  4.839   1.00 90.54  ? 798  PHE D CB  1 
ATOM   14031 C CG  . PHE D 1 723 ? -47.754 -4.134  4.365   1.00 90.95  ? 798  PHE D CG  1 
ATOM   14032 C CD1 . PHE D 1 723 ? -48.385 -5.361  4.247   1.00 88.96  ? 798  PHE D CD1 1 
ATOM   14033 C CD2 . PHE D 1 723 ? -48.459 -2.988  4.041   1.00 91.11  ? 798  PHE D CD2 1 
ATOM   14034 C CE1 . PHE D 1 723 ? -49.693 -5.446  3.813   1.00 88.31  ? 798  PHE D CE1 1 
ATOM   14035 C CE2 . PHE D 1 723 ? -49.769 -3.066  3.607   1.00 101.29 ? 798  PHE D CE2 1 
ATOM   14036 C CZ  . PHE D 1 723 ? -50.386 -4.297  3.493   1.00 102.97 ? 798  PHE D CZ  1 
ATOM   14037 N N   . SER D 1 724 ? -44.278 -4.622  7.848   1.00 96.96  ? 799  SER D N   1 
ATOM   14038 C CA  . SER D 1 724 ? -42.898 -4.842  8.245   1.00 96.74  ? 799  SER D CA  1 
ATOM   14039 C C   . SER D 1 724 ? -42.610 -6.339  8.337   1.00 105.55 ? 799  SER D C   1 
ATOM   14040 O O   . SER D 1 724 ? -43.481 -7.185  8.116   1.00 101.04 ? 799  SER D O   1 
ATOM   14041 C CB  . SER D 1 724 ? -42.612 -4.149  9.575   1.00 103.29 ? 799  SER D CB  1 
ATOM   14042 O OG  . SER D 1 724 ? -43.390 -4.711  10.618  1.00 106.11 ? 799  SER D OG  1 
ATOM   14043 N N   . HIS D 1 725 ? -41.359 -6.666  8.670   1.00 109.34 ? 800  HIS D N   1 
ATOM   14044 C CA  . HIS D 1 725 ? -40.970 -8.053  8.894   1.00 105.76 ? 800  HIS D CA  1 
ATOM   14045 C C   . HIS D 1 725 ? -41.812 -8.720  9.972   1.00 109.44 ? 800  HIS D C   1 
ATOM   14046 O O   . HIS D 1 725 ? -41.929 -9.951  9.980   1.00 111.30 ? 800  HIS D O   1 
ATOM   14047 C CB  . HIS D 1 725 ? -39.492 -8.111  9.276   1.00 120.07 ? 800  HIS D CB  1 
ATOM   14048 C CG  . HIS D 1 725 ? -39.058 -6.970  10.141  1.00 134.78 ? 800  HIS D CG  1 
ATOM   14049 N ND1 . HIS D 1 725 ? -39.521 -6.796  11.428  1.00 130.93 ? 800  HIS D ND1 1 
ATOM   14050 C CD2 . HIS D 1 725 ? -38.223 -5.932  9.899   1.00 139.62 ? 800  HIS D CD2 1 
ATOM   14051 C CE1 . HIS D 1 725 ? -38.983 -5.707  11.945  1.00 125.19 ? 800  HIS D CE1 1 
ATOM   14052 N NE2 . HIS D 1 725 ? -38.190 -5.164  11.038  1.00 130.61 ? 800  HIS D NE2 1 
ATOM   14053 N N   . GLN D 1 726 ? -42.399 -7.936  10.875  1.00 112.87 ? 801  GLN D N   1 
ATOM   14054 C CA  . GLN D 1 726 ? -43.236 -8.451  11.949  1.00 106.04 ? 801  GLN D CA  1 
ATOM   14055 C C   . GLN D 1 726 ? -44.604 -8.910  11.467  1.00 110.54 ? 801  GLN D C   1 
ATOM   14056 O O   . GLN D 1 726 ? -45.390 -9.400  12.283  1.00 120.84 ? 801  GLN D O   1 
ATOM   14057 C CB  . GLN D 1 726 ? -43.401 -7.378  13.027  1.00 103.36 ? 801  GLN D CB  1 
ATOM   14058 C CG  . GLN D 1 726 ? -42.106 -6.666  13.381  1.00 109.73 ? 801  GLN D CG  1 
ATOM   14059 C CD  . GLN D 1 726 ? -41.944 -6.438  14.869  1.00 133.51 ? 801  GLN D CD  1 
ATOM   14060 O OE1 . GLN D 1 726 ? -42.740 -6.920  15.673  1.00 152.25 ? 801  GLN D OE1 1 
ATOM   14061 N NE2 . GLN D 1 726 ? -40.908 -5.695  15.244  1.00 126.48 ? 801  GLN D NE2 1 
ATOM   14062 N N   . ILE D 1 727 ? -44.907 -8.764  10.174  1.00 112.79 ? 802  ILE D N   1 
ATOM   14063 C CA  . ILE D 1 727 ? -46.206 -9.173  9.654   1.00 111.91 ? 802  ILE D CA  1 
ATOM   14064 C C   . ILE D 1 727 ? -46.397 -10.681 9.730   1.00 120.42 ? 802  ILE D C   1 
ATOM   14065 O O   . ILE D 1 727 ? -47.538 -11.153 9.766   1.00 127.12 ? 802  ILE D O   1 
ATOM   14066 C CB  . ILE D 1 727 ? -46.390 -8.671  8.207   1.00 93.71  ? 802  ILE D CB  1 
ATOM   14067 C CG1 . ILE D 1 727 ? -47.872 -8.620  7.837   1.00 97.45  ? 802  ILE D CG1 1 
ATOM   14068 C CG2 . ILE D 1 727 ? -45.639 -9.554  7.227   1.00 103.90 ? 802  ILE D CG2 1 
ATOM   14069 C CD1 . ILE D 1 727 ? -48.130 -8.326  6.378   1.00 97.95  ? 802  ILE D CD1 1 
ATOM   14070 N N   . MET D 1 728 ? -45.310 -11.452 9.761   1.00 124.44 ? 803  MET D N   1 
ATOM   14071 C CA  . MET D 1 728 ? -45.375 -12.898 9.914   1.00 130.21 ? 803  MET D CA  1 
ATOM   14072 C C   . MET D 1 728 ? -44.965 -13.361 11.303  1.00 124.13 ? 803  MET D C   1 
ATOM   14073 O O   . MET D 1 728 ? -44.888 -14.572 11.538  1.00 126.49 ? 803  MET D O   1 
ATOM   14074 C CB  . MET D 1 728 ? -44.484 -13.589 8.873   1.00 133.80 ? 803  MET D CB  1 
ATOM   14075 C CG  . MET D 1 728 ? -43.041 -13.103 8.881   1.00 143.94 ? 803  MET D CG  1 
ATOM   14076 S SD  . MET D 1 728 ? -42.015 -13.874 7.615   1.00 152.35 ? 803  MET D SD  1 
ATOM   14077 C CE  . MET D 1 728 ? -41.814 -12.515 6.473   1.00 150.12 ? 803  MET D CE  1 
ATOM   14078 N N   . SER D 1 729 ? -44.699 -12.431 12.226  1.00 118.32 ? 804  SER D N   1 
ATOM   14079 C CA  . SER D 1 729 ? -44.168 -12.802 13.535  1.00 126.76 ? 804  SER D CA  1 
ATOM   14080 C C   . SER D 1 729 ? -45.136 -13.672 14.325  1.00 138.13 ? 804  SER D C   1 
ATOM   14081 O O   . SER D 1 729 ? -44.702 -14.497 15.136  1.00 159.46 ? 804  SER D O   1 
ATOM   14082 C CB  . SER D 1 729 ? -43.817 -11.547 14.337  1.00 117.42 ? 804  SER D CB  1 
ATOM   14083 O OG  . SER D 1 729 ? -42.595 -10.982 13.898  1.00 118.97 ? 804  SER D OG  1 
ATOM   14084 N N   . GLY D 1 730 ? -46.438 -13.508 14.113  1.00 125.21 ? 805  GLY D N   1 
ATOM   14085 C CA  . GLY D 1 730 ? -47.407 -14.306 14.837  1.00 132.59 ? 805  GLY D CA  1 
ATOM   14086 C C   . GLY D 1 730 ? -47.776 -15.589 14.125  1.00 133.95 ? 805  GLY D C   1 
ATOM   14087 O O   . GLY D 1 730 ? -48.897 -16.088 14.268  1.00 137.80 ? 805  GLY D O   1 
ATOM   14088 N N   . GLY D 1 731 ? -46.838 -16.142 13.359  1.00 125.74 ? 806  GLY D N   1 
ATOM   14089 C CA  . GLY D 1 731 ? -47.111 -17.325 12.573  1.00 127.25 ? 806  GLY D CA  1 
ATOM   14090 C C   . GLY D 1 731 ? -47.798 -17.063 11.255  1.00 136.86 ? 806  GLY D C   1 
ATOM   14091 O O   . GLY D 1 731 ? -48.252 -18.015 10.610  1.00 139.33 ? 806  GLY D O   1 
ATOM   14092 N N   . ARG D 1 732 ? -47.891 -15.803 10.833  1.00 136.47 ? 807  ARG D N   1 
ATOM   14093 C CA  . ARG D 1 732 ? -48.474 -15.462 9.540   1.00 141.21 ? 807  ARG D CA  1 
ATOM   14094 C C   . ARG D 1 732 ? -47.474 -15.704 8.416   1.00 137.94 ? 807  ARG D C   1 
ATOM   14095 O O   . ARG D 1 732 ? -47.195 -14.806 7.613   1.00 134.26 ? 807  ARG D O   1 
ATOM   14096 C CB  . ARG D 1 732 ? -48.944 -14.006 9.538   1.00 134.90 ? 807  ARG D CB  1 
ATOM   14097 C CG  . ARG D 1 732 ? -50.254 -13.751 10.279  1.00 127.78 ? 807  ARG D CG  1 
ATOM   14098 C CD  . ARG D 1 732 ? -50.003 -13.285 11.705  1.00 115.65 ? 807  ARG D CD  1 
ATOM   14099 N NE  . ARG D 1 732 ? -49.089 -12.152 11.770  1.00 120.04 ? 807  ARG D NE  1 
ATOM   14100 C CZ  . ARG D 1 732 ? -48.765 -11.517 12.888  1.00 120.05 ? 807  ARG D CZ  1 
ATOM   14101 N NH1 . ARG D 1 732 ? -49.310 -11.842 14.049  1.00 113.87 ? 807  ARG D NH1 1 
ATOM   14102 N NH2 . ARG D 1 732 ? -47.878 -10.528 12.840  1.00 119.86 ? 807  ARG D NH2 1 
ATOM   14103 N N   . ASP D 1 733 ? -46.931 -16.923 8.352   1.00 132.26 ? 808  ASP D N   1 
ATOM   14104 C CA  . ASP D 1 733 ? -46.025 -17.280 7.264   1.00 131.98 ? 808  ASP D CA  1 
ATOM   14105 C C   . ASP D 1 733 ? -46.706 -17.170 5.907   1.00 136.05 ? 808  ASP D C   1 
ATOM   14106 O O   . ASP D 1 733 ? -46.028 -16.997 4.888   1.00 132.76 ? 808  ASP D O   1 
ATOM   14107 C CB  . ASP D 1 733 ? -45.478 -18.689 7.472   1.00 131.75 ? 808  ASP D CB  1 
ATOM   14108 C CG  . ASP D 1 733 ? -44.734 -18.836 8.779   1.00 143.29 ? 808  ASP D CG  1 
ATOM   14109 O OD1 . ASP D 1 733 ? -45.354 -18.653 9.846   1.00 138.39 ? 808  ASP D OD1 1 
ATOM   14110 O OD2 . ASP D 1 733 ? -43.522 -19.135 8.734   1.00 148.83 ? 808  ASP D OD2 1 
ATOM   14111 N N   . MET D 1 734 ? -48.035 -17.283 5.872   1.00 134.02 ? 809  MET D N   1 
ATOM   14112 C CA  . MET D 1 734 ? -48.779 -16.929 4.667   1.00 127.72 ? 809  MET D CA  1 
ATOM   14113 C C   . MET D 1 734 ? -48.397 -15.556 4.136   1.00 127.40 ? 809  MET D C   1 
ATOM   14114 O O   . MET D 1 734 ? -48.163 -15.382 2.934   1.00 120.48 ? 809  MET D O   1 
ATOM   14115 C CB  . MET D 1 734 ? -50.275 -16.956 4.945   1.00 117.21 ? 809  MET D CB  1 
ATOM   14116 C CG  . MET D 1 734 ? -51.049 -16.848 3.670   1.00 129.94 ? 809  MET D CG  1 
ATOM   14117 S SD  . MET D 1 734 ? -52.663 -17.603 3.700   1.00 149.71 ? 809  MET D SD  1 
ATOM   14118 C CE  . MET D 1 734 ? -53.110 -17.350 1.994   1.00 158.07 ? 809  MET D CE  1 
ATOM   14119 N N   . LEU D 1 735 ? -48.358 -14.560 5.013   1.00 138.80 ? 810  LEU D N   1 
ATOM   14120 C CA  . LEU D 1 735 ? -48.119 -13.183 4.602   1.00 125.71 ? 810  LEU D CA  1 
ATOM   14121 C C   . LEU D 1 735 ? -46.647 -12.896 4.341   1.00 116.84 ? 810  LEU D C   1 
ATOM   14122 O O   . LEU D 1 735 ? -46.269 -11.724 4.243   1.00 114.68 ? 810  LEU D O   1 
ATOM   14123 C CB  . LEU D 1 735 ? -48.660 -12.227 5.667   1.00 123.02 ? 810  LEU D CB  1 
ATOM   14124 C CG  . LEU D 1 735 ? -50.112 -12.470 6.092   1.00 119.33 ? 810  LEU D CG  1 
ATOM   14125 C CD1 . LEU D 1 735 ? -50.606 -11.349 6.996   1.00 121.64 ? 810  LEU D CD1 1 
ATOM   14126 C CD2 . LEU D 1 735 ? -51.027 -12.638 4.882   1.00 129.13 ? 810  LEU D CD2 1 
ATOM   14127 N N   . GLU D 1 736 ? -45.818 -13.937 4.226   1.00 111.85 ? 811  GLU D N   1 
ATOM   14128 C CA  . GLU D 1 736 ? -44.383 -13.732 4.043   1.00 117.08 ? 811  GLU D CA  1 
ATOM   14129 C C   . GLU D 1 736 ? -44.041 -12.918 2.799   1.00 108.12 ? 811  GLU D C   1 
ATOM   14130 O O   . GLU D 1 736 ? -43.162 -12.045 2.899   1.00 104.68 ? 811  GLU D O   1 
ATOM   14131 C CB  . GLU D 1 736 ? -43.662 -15.089 4.033   1.00 127.61 ? 811  GLU D CB  1 
ATOM   14132 C CG  . GLU D 1 736 ? -42.137 -15.018 3.939   1.00 133.14 ? 811  GLU D CG  1 
ATOM   14133 C CD  . GLU D 1 736 ? -41.624 -14.957 2.508   1.00 136.70 ? 811  GLU D CD  1 
ATOM   14134 O OE1 . GLU D 1 736 ? -42.424 -15.162 1.572   1.00 139.09 ? 811  GLU D OE1 1 
ATOM   14135 O OE2 . GLU D 1 736 ? -40.414 -14.706 2.325   1.00 130.43 ? 811  GLU D OE2 1 
ATOM   14136 N N   . PRO D 1 737 ? -44.651 -13.132 1.628   1.00 96.47  ? 812  PRO D N   1 
ATOM   14137 C CA  . PRO D 1 737 ? -44.328 -12.257 0.488   1.00 93.87  ? 812  PRO D CA  1 
ATOM   14138 C C   . PRO D 1 737 ? -44.748 -10.811 0.698   1.00 105.19 ? 812  PRO D C   1 
ATOM   14139 O O   . PRO D 1 737 ? -44.223 -9.924  0.015   1.00 114.41 ? 812  PRO D O   1 
ATOM   14140 C CB  . PRO D 1 737 ? -45.091 -12.895 -0.681  1.00 101.37 ? 812  PRO D CB  1 
ATOM   14141 C CG  . PRO D 1 737 ? -45.363 -14.291 -0.258  1.00 107.17 ? 812  PRO D CG  1 
ATOM   14142 C CD  . PRO D 1 737 ? -45.525 -14.250 1.224   1.00 105.32 ? 812  PRO D CD  1 
ATOM   14143 N N   . LEU D 1 738 ? -45.665 -10.545 1.624   1.00 106.18 ? 813  LEU D N   1 
ATOM   14144 C CA  . LEU D 1 738 ? -46.200 -9.200  1.843   1.00 108.61 ? 813  LEU D CA  1 
ATOM   14145 C C   . LEU D 1 738 ? -45.352 -8.404  2.832   1.00 111.65 ? 813  LEU D C   1 
ATOM   14146 O O   . LEU D 1 738 ? -45.861 -7.829  3.793   1.00 124.24 ? 813  LEU D O   1 
ATOM   14147 C CB  . LEU D 1 738 ? -47.646 -9.293  2.320   1.00 107.58 ? 813  LEU D CB  1 
ATOM   14148 C CG  . LEU D 1 738 ? -48.652 -10.011 1.421   1.00 109.76 ? 813  LEU D CG  1 
ATOM   14149 C CD1 . LEU D 1 738 ? -49.940 -10.274 2.179   1.00 110.45 ? 813  LEU D CD1 1 
ATOM   14150 C CD2 . LEU D 1 738 ? -48.931 -9.190  0.174   1.00 114.70 ? 813  LEU D CD2 1 
ATOM   14151 N N   . VAL D 1 739 ? -44.042 -8.356  2.597   1.00 112.11 ? 814  VAL D N   1 
ATOM   14152 C CA  . VAL D 1 739 ? -43.118 -7.611  3.442   1.00 99.11  ? 814  VAL D CA  1 
ATOM   14153 C C   . VAL D 1 739 ? -42.461 -6.525  2.603   1.00 102.92 ? 814  VAL D C   1 
ATOM   14154 O O   . VAL D 1 739 ? -42.105 -6.754  1.442   1.00 125.59 ? 814  VAL D O   1 
ATOM   14155 C CB  . VAL D 1 739 ? -42.049 -8.519  4.081   1.00 78.09  ? 814  VAL D CB  1 
ATOM   14156 C CG1 . VAL D 1 739 ? -42.640 -9.286  5.247   1.00 82.01  ? 814  VAL D CG1 1 
ATOM   14157 C CG2 . VAL D 1 739 ? -41.442 -9.459  3.048   1.00 96.78  ? 814  VAL D CG2 1 
ATOM   14158 N N   . TYR D 1 740 ? -42.301 -5.346  3.194   1.00 77.28  ? 815  TYR D N   1 
ATOM   14159 C CA  . TYR D 1 740 ? -41.691 -4.207  2.523   1.00 88.82  ? 815  TYR D CA  1 
ATOM   14160 C C   . TYR D 1 740 ? -40.535 -3.719  3.384   1.00 101.25 ? 815  TYR D C   1 
ATOM   14161 O O   . TYR D 1 740 ? -40.747 -3.229  4.499   1.00 104.49 ? 815  TYR D O   1 
ATOM   14162 C CB  . TYR D 1 740 ? -42.711 -3.095  2.280   1.00 96.05  ? 815  TYR D CB  1 
ATOM   14163 C CG  . TYR D 1 740 ? -42.206 -1.976  1.392   1.00 100.06 ? 815  TYR D CG  1 
ATOM   14164 C CD1 . TYR D 1 740 ? -41.252 -1.072  1.843   1.00 99.58  ? 815  TYR D CD1 1 
ATOM   14165 C CD2 . TYR D 1 740 ? -42.671 -1.841  0.090   1.00 104.10 ? 815  TYR D CD2 1 
ATOM   14166 C CE1 . TYR D 1 740 ? -40.785 -0.057  1.031   1.00 113.22 ? 815  TYR D CE1 1 
ATOM   14167 C CE2 . TYR D 1 740 ? -42.209 -0.831  -0.730  1.00 109.20 ? 815  TYR D CE2 1 
ATOM   14168 C CZ  . TYR D 1 740 ? -41.268 0.057   -0.256  1.00 118.30 ? 815  TYR D CZ  1 
ATOM   14169 O OH  . TYR D 1 740 ? -40.808 1.064   -1.073  1.00 120.23 ? 815  TYR D OH  1 
ATOM   14170 N N   . THR D 1 741 ? -39.314 -3.854  2.866   1.00 105.45 ? 816  THR D N   1 
ATOM   14171 C CA  . THR D 1 741 ? -38.136 -3.299  3.516   1.00 86.23  ? 816  THR D CA  1 
ATOM   14172 C C   . THR D 1 741 ? -37.864 -1.914  2.947   1.00 93.99  ? 816  THR D C   1 
ATOM   14173 O O   . THR D 1 741 ? -37.581 -1.798  1.746   1.00 105.97 ? 816  THR D O   1 
ATOM   14174 C CB  . THR D 1 741 ? -36.929 -4.196  3.303   1.00 95.81  ? 816  THR D CB  1 
ATOM   14175 O OG1 . THR D 1 741 ? -37.224 -5.515  3.774   1.00 95.87  ? 816  THR D OG1 1 
ATOM   14176 C CG2 . THR D 1 741 ? -35.724 -3.650  4.054   1.00 111.37 ? 816  THR D CG2 1 
ATOM   14177 N N   . PRO D 1 742 ? -37.948 -0.853  3.746   1.00 86.12  ? 817  PRO D N   1 
ATOM   14178 C CA  . PRO D 1 742 ? -37.742 0.498   3.205   1.00 91.42  ? 817  PRO D CA  1 
ATOM   14179 C C   . PRO D 1 742 ? -36.341 0.665   2.633   1.00 102.76 ? 817  PRO D C   1 
ATOM   14180 O O   . PRO D 1 742 ? -35.340 0.393   3.301   1.00 96.03  ? 817  PRO D O   1 
ATOM   14181 C CB  . PRO D 1 742 ? -37.970 1.409   4.419   1.00 80.78  ? 817  PRO D CB  1 
ATOM   14182 C CG  . PRO D 1 742 ? -37.894 0.515   5.617   1.00 84.63  ? 817  PRO D CG  1 
ATOM   14183 C CD  . PRO D 1 742 ? -38.333 -0.837  5.167   1.00 86.58  ? 817  PRO D CD  1 
ATOM   14184 N N   . ASP D 1 743 ? -36.278 1.108   1.380   1.00 111.46 ? 818  ASP D N   1 
ATOM   14185 C CA  . ASP D 1 743 ? -34.997 1.357   0.740   1.00 100.99 ? 818  ASP D CA  1 
ATOM   14186 C C   . ASP D 1 743 ? -34.283 2.521   1.420   1.00 97.35  ? 818  ASP D C   1 
ATOM   14187 O O   . ASP D 1 743 ? -34.874 3.290   2.183   1.00 103.58 ? 818  ASP D O   1 
ATOM   14188 C CB  . ASP D 1 743 ? -35.185 1.648   -0.749  1.00 103.95 ? 818  ASP D CB  1 
ATOM   14189 C CG  . ASP D 1 743 ? -36.369 2.554   -1.019  1.00 126.77 ? 818  ASP D CG  1 
ATOM   14190 O OD1 . ASP D 1 743 ? -37.515 2.127   -0.762  1.00 134.49 ? 818  ASP D OD1 1 
ATOM   14191 O OD2 . ASP D 1 743 ? -36.154 3.690   -1.490  1.00 121.41 ? 818  ASP D OD2 1 
ATOM   14192 N N   . SER D 1 744 ? -32.987 2.644   1.132   1.00 88.45  ? 819  SER D N   1 
ATOM   14193 C CA  . SER D 1 744 ? -32.182 3.660   1.800   1.00 96.31  ? 819  SER D CA  1 
ATOM   14194 C C   . SER D 1 744 ? -32.671 5.064   1.469   1.00 104.70 ? 819  SER D C   1 
ATOM   14195 O O   . SER D 1 744 ? -32.632 5.959   2.323   1.00 104.67 ? 819  SER D O   1 
ATOM   14196 C CB  . SER D 1 744 ? -30.717 3.499   1.412   1.00 111.15 ? 819  SER D CB  1 
ATOM   14197 O OG  . SER D 1 744 ? -30.306 2.147   1.520   1.00 124.03 ? 819  SER D OG  1 
ATOM   14198 N N   . SER D 1 745 ? -33.124 5.281   0.232   1.00 108.85 ? 820  SER D N   1 
ATOM   14199 C CA  . SER D 1 745 ? -33.702 6.573   -0.123  1.00 110.71 ? 820  SER D CA  1 
ATOM   14200 C C   . SER D 1 745 ? -34.949 6.856   0.692   1.00 114.23 ? 820  SER D C   1 
ATOM   14201 O O   . SER D 1 745 ? -35.173 7.989   1.126   1.00 111.13 ? 820  SER D O   1 
ATOM   14202 C CB  . SER D 1 745 ? -34.059 6.613   -1.600  1.00 128.64 ? 820  SER D CB  1 
ATOM   14203 O OG  . SER D 1 745 ? -35.041 5.640   -1.900  1.00 114.59 ? 820  SER D OG  1 
ATOM   14204 N N   . LEU D 1 746 ? -35.790 5.840   0.880   1.00 118.43 ? 821  LEU D N   1 
ATOM   14205 C CA  . LEU D 1 746 ? -37.025 6.028   1.628   1.00 107.52 ? 821  LEU D CA  1 
ATOM   14206 C C   . LEU D 1 746 ? -36.726 6.418   3.070   1.00 105.21 ? 821  LEU D C   1 
ATOM   14207 O O   . LEU D 1 746 ? -37.337 7.344   3.616   1.00 101.74 ? 821  LEU D O   1 
ATOM   14208 C CB  . LEU D 1 746 ? -37.869 4.755   1.562   1.00 92.45  ? 821  LEU D CB  1 
ATOM   14209 C CG  . LEU D 1 746 ? -39.190 4.770   2.328   1.00 90.07  ? 821  LEU D CG  1 
ATOM   14210 C CD1 . LEU D 1 746 ? -39.995 5.975   1.903   1.00 85.73  ? 821  LEU D CD1 1 
ATOM   14211 C CD2 . LEU D 1 746 ? -39.974 3.487   2.078   1.00 94.29  ? 821  LEU D CD2 1 
ATOM   14212 N N   . GLN D 1 747 ? -35.761 5.736   3.689   1.00 103.39 ? 822  GLN D N   1 
ATOM   14213 C CA  . GLN D 1 747 ? -35.342 6.083   5.041   1.00 97.74  ? 822  GLN D CA  1 
ATOM   14214 C C   . GLN D 1 747 ? -34.766 7.494   5.092   1.00 93.65  ? 822  GLN D C   1 
ATOM   14215 O O   . GLN D 1 747 ? -35.061 8.265   6.017   1.00 102.69 ? 822  GLN D O   1 
ATOM   14216 C CB  . GLN D 1 747 ? -34.313 5.063   5.530   1.00 79.27  ? 822  GLN D CB  1 
ATOM   14217 C CG  . GLN D 1 747 ? -34.812 3.626   5.499   1.00 79.37  ? 822  GLN D CG  1 
ATOM   14218 C CD  . GLN D 1 747 ? -33.860 2.664   6.180   1.00 83.36  ? 822  GLN D CD  1 
ATOM   14219 O OE1 . GLN D 1 747 ? -32.808 3.063   6.679   1.00 91.05  ? 822  GLN D OE1 1 
ATOM   14220 N NE2 . GLN D 1 747 ? -34.217 1.385   6.187   1.00 61.97  ? 822  GLN D NE2 1 
ATOM   14221 N N   . SER D 1 748 ? -33.946 7.850   4.097   1.00 84.80  ? 823  SER D N   1 
ATOM   14222 C CA  . SER D 1 748 ? -33.373 9.191   4.036   1.00 96.26  ? 823  SER D CA  1 
ATOM   14223 C C   . SER D 1 748 ? -34.460 10.250  3.930   1.00 99.66  ? 823  SER D C   1 
ATOM   14224 O O   . SER D 1 748 ? -34.403 11.277  4.612   1.00 93.02  ? 823  SER D O   1 
ATOM   14225 C CB  . SER D 1 748 ? -32.415 9.294   2.849   1.00 113.09 ? 823  SER D CB  1 
ATOM   14226 O OG  . SER D 1 748 ? -31.756 10.548  2.825   1.00 125.74 ? 823  SER D OG  1 
ATOM   14227 N N   . GLU D 1 749 ? -35.466 10.004  3.091   1.00 107.83 ? 824  GLU D N   1 
ATOM   14228 C CA  . GLU D 1 749 ? -36.534 10.975  2.884   1.00 115.07 ? 824  GLU D CA  1 
ATOM   14229 C C   . GLU D 1 749 ? -37.416 11.092  4.120   1.00 106.08 ? 824  GLU D C   1 
ATOM   14230 O O   . GLU D 1 749 ? -37.892 12.183  4.449   1.00 105.36 ? 824  GLU D O   1 
ATOM   14231 C CB  . GLU D 1 749 ? -37.367 10.574  1.665   1.00 122.44 ? 824  GLU D CB  1 
ATOM   14232 C CG  . GLU D 1 749 ? -38.352 11.631  1.197   1.00 137.13 ? 824  GLU D CG  1 
ATOM   14233 C CD  . GLU D 1 749 ? -37.669 12.927  0.817   1.00 141.21 ? 824  GLU D CD  1 
ATOM   14234 O OE1 . GLU D 1 749 ? -36.874 12.915  -0.146  1.00 134.37 ? 824  GLU D OE1 1 
ATOM   14235 O OE2 . GLU D 1 749 ? -37.922 13.956  1.478   1.00 147.26 ? 824  GLU D OE2 1 
ATOM   14236 N N   . LEU D 1 750 ? -37.638 9.979   4.823   1.00 91.49  ? 825  LEU D N   1 
ATOM   14237 C CA  . LEU D 1 750 ? -38.417 10.024  6.056   1.00 85.84  ? 825  LEU D CA  1 
ATOM   14238 C C   . LEU D 1 750 ? -37.689 10.826  7.130   1.00 93.18  ? 825  LEU D C   1 
ATOM   14239 O O   . LEU D 1 750 ? -38.275 11.713  7.773   1.00 100.40 ? 825  LEU D O   1 
ATOM   14240 C CB  . LEU D 1 750 ? -38.703 8.598   6.535   1.00 76.69  ? 825  LEU D CB  1 
ATOM   14241 C CG  . LEU D 1 750 ? -39.547 7.722   5.600   1.00 79.89  ? 825  LEU D CG  1 
ATOM   14242 C CD1 . LEU D 1 750 ? -39.778 6.334   6.184   1.00 79.68  ? 825  LEU D CD1 1 
ATOM   14243 C CD2 . LEU D 1 750 ? -40.866 8.384   5.238   1.00 95.79  ? 825  LEU D CD2 1 
ATOM   14244 N N   . LEU D 1 751 ? -36.400 10.532  7.334   1.00 85.52  ? 826  LEU D N   1 
ATOM   14245 C CA  . LEU D 1 751 ? -35.608 11.301  8.289   1.00 86.61  ? 826  LEU D CA  1 
ATOM   14246 C C   . LEU D 1 751 ? -35.529 12.769  7.886   1.00 94.91  ? 826  LEU D C   1 
ATOM   14247 O O   . LEU D 1 751 ? -35.531 13.657  8.744   1.00 100.37 ? 826  LEU D O   1 
ATOM   14248 C CB  . LEU D 1 751 ? -34.209 10.700  8.412   1.00 88.88  ? 826  LEU D CB  1 
ATOM   14249 C CG  . LEU D 1 751 ? -33.246 11.438  9.342   1.00 93.52  ? 826  LEU D CG  1 
ATOM   14250 C CD1 . LEU D 1 751 ? -33.755 11.398  10.768  1.00 83.90  ? 826  LEU D CD1 1 
ATOM   14251 C CD2 . LEU D 1 751 ? -31.853 10.840  9.254   1.00 112.40 ? 826  LEU D CD2 1 
ATOM   14252 N N   . SER D 1 752 ? -35.469 13.042  6.581   1.00 90.91  ? 827  SER D N   1 
ATOM   14253 C CA  . SER D 1 752 ? -35.441 14.420  6.105   1.00 92.89  ? 827  SER D CA  1 
ATOM   14254 C C   . SER D 1 752 ? -36.755 15.130  6.392   1.00 94.62  ? 827  SER D C   1 
ATOM   14255 O O   . SER D 1 752 ? -36.759 16.316  6.739   1.00 96.50  ? 827  SER D O   1 
ATOM   14256 C CB  . SER D 1 752 ? -35.133 14.446  4.609   1.00 105.95 ? 827  SER D CB  1 
ATOM   14257 O OG  . SER D 1 752 ? -35.273 15.752  4.082   1.00 125.47 ? 827  SER D OG  1 
ATOM   14258 N N   . PHE D 1 753 ? -37.879 14.429  6.235   1.00 94.36  ? 828  PHE D N   1 
ATOM   14259 C CA  . PHE D 1 753 ? -39.163 14.991  6.637   1.00 95.72  ? 828  PHE D CA  1 
ATOM   14260 C C   . PHE D 1 753 ? -39.144 15.355  8.113   1.00 94.69  ? 828  PHE D C   1 
ATOM   14261 O O   . PHE D 1 753 ? -39.574 16.447  8.501   1.00 92.48  ? 828  PHE D O   1 
ATOM   14262 C CB  . PHE D 1 753 ? -40.295 14.004  6.335   1.00 92.16  ? 828  PHE D CB  1 
ATOM   14263 C CG  . PHE D 1 753 ? -41.669 14.518  6.690   1.00 85.38  ? 828  PHE D CG  1 
ATOM   14264 C CD1 . PHE D 1 753 ? -42.123 14.501  8.001   1.00 84.08  ? 828  PHE D CD1 1 
ATOM   14265 C CD2 . PHE D 1 753 ? -42.503 15.026  5.709   1.00 90.71  ? 828  PHE D CD2 1 
ATOM   14266 C CE1 . PHE D 1 753 ? -43.376 14.978  8.323   1.00 88.67  ? 828  PHE D CE1 1 
ATOM   14267 C CE2 . PHE D 1 753 ? -43.760 15.503  6.026   1.00 89.39  ? 828  PHE D CE2 1 
ATOM   14268 C CZ  . PHE D 1 753 ? -44.197 15.478  7.335   1.00 95.93  ? 828  PHE D CZ  1 
ATOM   14269 N N   . ILE D 1 754 ? -38.654 14.440  8.952   1.00 97.75  ? 829  ILE D N   1 
ATOM   14270 C CA  . ILE D 1 754 ? -38.593 14.718  10.388  1.00 101.22 ? 829  ILE D CA  1 
ATOM   14271 C C   . ILE D 1 754 ? -37.740 15.954  10.658  1.00 94.79  ? 829  ILE D C   1 
ATOM   14272 O O   . ILE D 1 754 ? -38.126 16.840  11.430  1.00 91.34  ? 829  ILE D O   1 
ATOM   14273 C CB  . ILE D 1 754 ? -38.070 13.493  11.158  1.00 95.42  ? 829  ILE D CB  1 
ATOM   14274 C CG1 . ILE D 1 754 ? -39.058 12.334  11.037  1.00 85.49  ? 829  ILE D CG1 1 
ATOM   14275 C CG2 . ILE D 1 754 ? -37.843 13.846  12.620  1.00 101.26 ? 829  ILE D CG2 1 
ATOM   14276 C CD1 . ILE D 1 754 ? -40.430 12.660  11.585  1.00 76.47  ? 829  ILE D CD1 1 
ATOM   14277 N N   . LEU D 1 755 ? -36.573 16.037  10.015  1.00 94.67  ? 830  LEU D N   1 
ATOM   14278 C CA  . LEU D 1 755 ? -35.665 17.152  10.270  1.00 87.35  ? 830  LEU D CA  1 
ATOM   14279 C C   . LEU D 1 755 ? -36.254 18.472  9.790   1.00 88.33  ? 830  LEU D C   1 
ATOM   14280 O O   . LEU D 1 755 ? -36.098 19.506  10.450  1.00 95.27  ? 830  LEU D O   1 
ATOM   14281 C CB  . LEU D 1 755 ? -34.315 16.894  9.600   1.00 75.86  ? 830  LEU D CB  1 
ATOM   14282 C CG  . LEU D 1 755 ? -33.547 15.649  10.046  1.00 79.44  ? 830  LEU D CG  1 
ATOM   14283 C CD1 . LEU D 1 755 ? -32.134 15.663  9.490   1.00 87.34  ? 830  LEU D CD1 1 
ATOM   14284 C CD2 . LEU D 1 755 ? -33.527 15.545  11.563  1.00 95.95  ? 830  LEU D CD2 1 
ATOM   14285 N N   . ASP D 1 756 ? -36.936 18.457  8.644   1.00 90.25  ? 831  ASP D N   1 
ATOM   14286 C CA  . ASP D 1 756 ? -37.462 19.688  8.065   1.00 92.79  ? 831  ASP D CA  1 
ATOM   14287 C C   . ASP D 1 756 ? -38.747 20.134  8.751   1.00 92.64  ? 831  ASP D C   1 
ATOM   14288 O O   . ASP D 1 756 ? -38.975 21.336  8.922   1.00 91.42  ? 831  ASP D O   1 
ATOM   14289 C CB  . ASP D 1 756 ? -37.704 19.503  6.566   1.00 90.81  ? 831  ASP D CB  1 
ATOM   14290 C CG  . ASP D 1 756 ? -36.433 19.187  5.802   1.00 98.46  ? 831  ASP D CG  1 
ATOM   14291 O OD1 . ASP D 1 756 ? -35.343 19.232  6.410   1.00 108.08 ? 831  ASP D OD1 1 
ATOM   14292 O OD2 . ASP D 1 756 ? -36.525 18.886  4.593   1.00 101.75 ? 831  ASP D OD2 1 
ATOM   14293 N N   . HIS D 1 757 ? -39.597 19.185  9.147   1.00 98.51  ? 832  HIS D N   1 
ATOM   14294 C CA  . HIS D 1 757 ? -40.924 19.497  9.669   1.00 105.77 ? 832  HIS D CA  1 
ATOM   14295 C C   . HIS D 1 757 ? -40.984 19.427  11.191  1.00 106.72 ? 832  HIS D C   1 
ATOM   14296 O O   . HIS D 1 757 ? -41.353 20.408  11.844  1.00 106.37 ? 832  HIS D O   1 
ATOM   14297 C CB  . HIS D 1 757 ? -41.961 18.547  9.054   1.00 94.70  ? 832  HIS D CB  1 
ATOM   14298 C CG  . HIS D 1 757 ? -42.078 18.663  7.566   1.00 93.37  ? 832  HIS D CG  1 
ATOM   14299 N ND1 . HIS D 1 757 ? -43.208 19.145  6.943   1.00 105.92 ? 832  HIS D ND1 1 
ATOM   14300 C CD2 . HIS D 1 757 ? -41.206 18.354  6.577   1.00 98.66  ? 832  HIS D CD2 1 
ATOM   14301 C CE1 . HIS D 1 757 ? -43.027 19.132  5.635   1.00 106.65 ? 832  HIS D CE1 1 
ATOM   14302 N NE2 . HIS D 1 757 ? -41.821 18.656  5.386   1.00 109.98 ? 832  HIS D NE2 1 
ATOM   14303 N N   . VAL D 1 758 ? -40.633 18.276  11.769  1.00 99.26  ? 833  VAL D N   1 
ATOM   14304 C CA  . VAL D 1 758 ? -40.780 18.088  13.211  1.00 90.30  ? 833  VAL D CA  1 
ATOM   14305 C C   . VAL D 1 758 ? -39.850 19.024  13.972  1.00 94.96  ? 833  VAL D C   1 
ATOM   14306 O O   . VAL D 1 758 ? -40.282 19.776  14.853  1.00 99.27  ? 833  VAL D O   1 
ATOM   14307 C CB  . VAL D 1 758 ? -40.533 16.616  13.589  1.00 87.24  ? 833  VAL D CB  1 
ATOM   14308 C CG1 . VAL D 1 758 ? -40.395 16.472  15.094  1.00 95.76  ? 833  VAL D CG1 1 
ATOM   14309 C CG2 . VAL D 1 758 ? -41.664 15.746  13.069  1.00 85.75  ? 833  VAL D CG2 1 
ATOM   14310 N N   . PHE D 1 759 ? -38.560 18.996  13.640  1.00 95.35  ? 834  PHE D N   1 
ATOM   14311 C CA  . PHE D 1 759 ? -37.555 19.785  14.351  1.00 89.04  ? 834  PHE D CA  1 
ATOM   14312 C C   . PHE D 1 759 ? -37.428 21.149  13.682  1.00 97.08  ? 834  PHE D C   1 
ATOM   14313 O O   . PHE D 1 759 ? -36.579 21.368  12.817  1.00 107.21 ? 834  PHE D O   1 
ATOM   14314 C CB  . PHE D 1 759 ? -36.223 19.047  14.384  1.00 84.68  ? 834  PHE D CB  1 
ATOM   14315 C CG  . PHE D 1 759 ? -36.258 17.769  15.174  1.00 85.58  ? 834  PHE D CG  1 
ATOM   14316 C CD1 . PHE D 1 759 ? -36.633 17.773  16.507  1.00 87.92  ? 834  PHE D CD1 1 
ATOM   14317 C CD2 . PHE D 1 759 ? -35.913 16.562  14.585  1.00 92.39  ? 834  PHE D CD2 1 
ATOM   14318 C CE1 . PHE D 1 759 ? -36.664 16.599  17.238  1.00 100.58 ? 834  PHE D CE1 1 
ATOM   14319 C CE2 . PHE D 1 759 ? -35.942 15.384  15.311  1.00 91.81  ? 834  PHE D CE2 1 
ATOM   14320 C CZ  . PHE D 1 759 ? -36.317 15.403  16.639  1.00 101.06 ? 834  PHE D CZ  1 
ATOM   14321 N N   . ILE D 1 760 ? -38.287 22.079  14.091  1.00 97.08  ? 835  ILE D N   1 
ATOM   14322 C CA  . ILE D 1 760 ? -38.231 23.470  13.659  1.00 99.33  ? 835  ILE D CA  1 
ATOM   14323 C C   . ILE D 1 760 ? -38.028 24.332  14.897  1.00 106.44 ? 835  ILE D C   1 
ATOM   14324 O O   . ILE D 1 760 ? -38.772 24.205  15.876  1.00 124.34 ? 835  ILE D O   1 
ATOM   14325 C CB  . ILE D 1 760 ? -39.503 23.879  12.892  1.00 102.55 ? 835  ILE D CB  1 
ATOM   14326 C CG1 . ILE D 1 760 ? -40.752 23.341  13.593  1.00 105.06 ? 835  ILE D CG1 1 
ATOM   14327 C CG2 . ILE D 1 760 ? -39.445 23.374  11.460  1.00 104.22 ? 835  ILE D CG2 1 
ATOM   14328 C CD1 . ILE D 1 760 ? -42.050 23.843  13.000  1.00 110.00 ? 835  ILE D CD1 1 
ATOM   14329 N N   . GLU D 1 761 ? -37.019 25.196  14.859  1.00 117.72 ? 836  GLU D N   1 
ATOM   14330 C CA  . GLU D 1 761 ? -36.593 25.914  16.051  1.00 133.63 ? 836  GLU D CA  1 
ATOM   14331 C C   . GLU D 1 761 ? -37.357 27.225  16.219  1.00 129.99 ? 836  GLU D C   1 
ATOM   14332 O O   . GLU D 1 761 ? -37.957 27.753  15.279  1.00 111.76 ? 836  GLU D O   1 
ATOM   14333 C CB  . GLU D 1 761 ? -35.088 26.190  16.009  1.00 137.10 ? 836  GLU D CB  1 
ATOM   14334 C CG  . GLU D 1 761 ? -34.650 27.151  14.918  1.00 139.72 ? 836  GLU D CG  1 
ATOM   14335 C CD  . GLU D 1 761 ? -33.141 27.273  14.832  1.00 142.26 ? 836  GLU D CD  1 
ATOM   14336 O OE1 . GLU D 1 761 ? -32.464 26.225  14.750  1.00 139.71 ? 836  GLU D OE1 1 
ATOM   14337 O OE2 . GLU D 1 761 ? -32.632 28.413  14.856  1.00 145.55 ? 836  GLU D OE2 1 
ATOM   14338 N N   . GLN D 1 762 ? -37.321 27.740  17.447  1.00 134.84 ? 837  GLN D N   1 
ATOM   14339 C CA  . GLN D 1 762 ? -37.927 29.020  17.818  1.00 126.07 ? 837  GLN D CA  1 
ATOM   14340 C C   . GLN D 1 762 ? -39.393 29.125  17.406  1.00 122.80 ? 837  GLN D C   1 
ATOM   14341 O O   . GLN D 1 762 ? -40.224 29.621  18.167  1.00 111.36 ? 837  GLN D O   1 
ATOM   14342 C CB  . GLN D 1 762 ? -37.130 30.181  17.216  1.00 126.98 ? 837  GLN D CB  1 
ATOM   14343 C CG  . GLN D 1 762 ? -35.652 30.169  17.583  1.00 140.20 ? 837  GLN D CG  1 
ATOM   14344 C CD  . GLN D 1 762 ? -34.836 31.169  16.784  1.00 152.06 ? 837  GLN D CD  1 
ATOM   14345 O OE1 . GLN D 1 762 ? -34.043 31.928  17.343  1.00 160.17 ? 837  GLN D OE1 1 
ATOM   14346 N NE2 . GLN D 1 762 ? -35.029 31.176  15.470  1.00 153.21 ? 837  GLN D NE2 1 
ATOM   14347 N N   . GLU D 1 776 ? -52.058 30.868  18.668  1.00 137.97 ? 851  GLU D N   1 
ATOM   14348 C CA  . GLU D 1 776 ? -51.852 30.670  20.099  1.00 144.76 ? 851  GLU D CA  1 
ATOM   14349 C C   . GLU D 1 776 ? -52.140 29.221  20.511  1.00 146.29 ? 851  GLU D C   1 
ATOM   14350 O O   . GLU D 1 776 ? -51.212 28.420  20.621  1.00 139.61 ? 851  GLU D O   1 
ATOM   14351 C CB  . GLU D 1 776 ? -52.703 31.668  20.892  1.00 142.52 ? 851  GLU D CB  1 
ATOM   14352 C CG  . GLU D 1 776 ? -54.028 32.031  20.238  1.00 137.99 ? 851  GLU D CG  1 
ATOM   14353 C CD  . GLU D 1 776 ? -54.626 33.302  20.810  1.00 135.96 ? 851  GLU D CD  1 
ATOM   14354 O OE1 . GLU D 1 776 ? -53.894 34.047  21.497  1.00 132.71 ? 851  GLU D OE1 1 
ATOM   14355 O OE2 . GLU D 1 776 ? -55.822 33.564  20.565  1.00 124.94 ? 851  GLU D OE2 1 
ATOM   14356 N N   . ALA D 1 777 ? -53.408 28.871  20.736  1.00 141.27 ? 852  ALA D N   1 
ATOM   14357 C CA  . ALA D 1 777 ? -53.736 27.468  20.986  1.00 133.87 ? 852  ALA D CA  1 
ATOM   14358 C C   . ALA D 1 777 ? -53.524 26.622  19.735  1.00 138.72 ? 852  ALA D C   1 
ATOM   14359 O O   . ALA D 1 777 ? -53.211 25.423  19.828  1.00 136.88 ? 852  ALA D O   1 
ATOM   14360 C CB  . ALA D 1 777 ? -55.175 27.342  21.484  1.00 129.75 ? 852  ALA D CB  1 
ATOM   14361 N N   . SER D 1 778 ? -53.680 27.235  18.560  1.00 137.51 ? 853  SER D N   1 
ATOM   14362 C CA  . SER D 1 778 ? -53.392 26.538  17.314  1.00 142.40 ? 853  SER D CA  1 
ATOM   14363 C C   . SER D 1 778 ? -51.938 26.088  17.257  1.00 137.72 ? 853  SER D C   1 
ATOM   14364 O O   . SER D 1 778 ? -51.630 25.057  16.648  1.00 131.84 ? 853  SER D O   1 
ATOM   14365 C CB  . SER D 1 778 ? -53.727 27.440  16.125  1.00 151.47 ? 853  SER D CB  1 
ATOM   14366 O OG  . SER D 1 778 ? -53.559 26.753  14.899  1.00 156.11 ? 853  SER D OG  1 
ATOM   14367 N N   . LYS D 1 779 ? -51.032 26.836  17.895  1.00 129.46 ? 854  LYS D N   1 
ATOM   14368 C CA  . LYS D 1 779 ? -49.645 26.390  17.981  1.00 131.78 ? 854  LYS D CA  1 
ATOM   14369 C C   . LYS D 1 779 ? -49.537 25.090  18.769  1.00 126.06 ? 854  LYS D C   1 
ATOM   14370 O O   . LYS D 1 779 ? -48.757 24.200  18.410  1.00 124.84 ? 854  LYS D O   1 
ATOM   14371 C CB  . LYS D 1 779 ? -48.777 27.473  18.620  1.00 145.63 ? 854  LYS D CB  1 
ATOM   14372 C CG  . LYS D 1 779 ? -48.452 28.643  17.699  1.00 142.13 ? 854  LYS D CG  1 
ATOM   14373 C CD  . LYS D 1 779 ? -47.959 29.876  18.462  1.00 142.74 ? 854  LYS D CD  1 
ATOM   14374 C CE  . LYS D 1 779 ? -47.180 29.541  19.738  1.00 154.50 ? 854  LYS D CE  1 
ATOM   14375 N NZ  . LYS D 1 779 ? -46.035 28.597  19.536  1.00 168.80 ? 854  LYS D NZ  1 
ATOM   14376 N N   . ILE D 1 780 ? -50.320 24.960  19.842  1.00 121.50 ? 855  ILE D N   1 
ATOM   14377 C CA  . ILE D 1 780 ? -50.322 23.725  20.622  1.00 117.79 ? 855  ILE D CA  1 
ATOM   14378 C C   . ILE D 1 780 ? -50.852 22.571  19.778  1.00 111.76 ? 855  ILE D C   1 
ATOM   14379 O O   . ILE D 1 780 ? -50.314 21.452  19.809  1.00 109.38 ? 855  ILE D O   1 
ATOM   14380 C CB  . ILE D 1 780 ? -51.145 23.916  21.911  1.00 114.37 ? 855  ILE D CB  1 
ATOM   14381 C CG1 . ILE D 1 780 ? -50.720 25.197  22.640  1.00 117.42 ? 855  ILE D CG1 1 
ATOM   14382 C CG2 . ILE D 1 780 ? -50.986 22.723  22.833  1.00 110.06 ? 855  ILE D CG2 1 
ATOM   14383 C CD1 . ILE D 1 780 ? -49.231 25.291  22.922  1.00 122.43 ? 855  ILE D CD1 1 
ATOM   14384 N N   . GLU D 1 781 ? -51.911 22.826  19.003  1.00 111.68 ? 856  GLU D N   1 
ATOM   14385 C CA  . GLU D 1 781 ? -52.436 21.800  18.101  1.00 107.69 ? 856  GLU D CA  1 
ATOM   14386 C C   . GLU D 1 781 ? -51.375 21.352  17.095  1.00 106.34 ? 856  GLU D C   1 
ATOM   14387 O O   . GLU D 1 781 ? -51.189 20.148  16.847  1.00 112.79 ? 856  GLU D O   1 
ATOM   14388 C CB  . GLU D 1 781 ? -53.673 22.341  17.382  1.00 113.17 ? 856  GLU D CB  1 
ATOM   14389 C CG  . GLU D 1 781 ? -54.783 22.798  18.323  1.00 132.26 ? 856  GLU D CG  1 
ATOM   14390 C CD  . GLU D 1 781 ? -56.076 23.126  17.598  1.00 136.85 ? 856  GLU D CD  1 
ATOM   14391 O OE1 . GLU D 1 781 ? -56.132 24.180  16.930  1.00 136.23 ? 856  GLU D OE1 1 
ATOM   14392 O OE2 . GLU D 1 781 ? -57.037 22.336  17.701  1.00 131.18 ? 856  GLU D OE2 1 
ATOM   14393 N N   . ALA D 1 782 ? -50.668 22.316  16.503  1.00 101.24 ? 857  ALA D N   1 
ATOM   14394 C CA  . ALA D 1 782 ? -49.617 21.991  15.543  1.00 106.31 ? 857  ALA D CA  1 
ATOM   14395 C C   . ALA D 1 782 ? -48.492 21.201  16.200  1.00 100.75 ? 857  ALA D C   1 
ATOM   14396 O O   . ALA D 1 782 ? -47.913 20.297  15.584  1.00 98.09  ? 857  ALA D O   1 
ATOM   14397 C CB  . ALA D 1 782 ? -49.075 23.272  14.913  1.00 121.43 ? 857  ALA D CB  1 
ATOM   14398 N N   . LEU D 1 783 ? -48.158 21.541  17.448  1.00 97.53  ? 858  LEU D N   1 
ATOM   14399 C CA  . LEU D 1 783 ? -47.167 20.763  18.184  1.00 95.37  ? 858  LEU D CA  1 
ATOM   14400 C C   . LEU D 1 783 ? -47.615 19.319  18.351  1.00 93.13  ? 858  LEU D C   1 
ATOM   14401 O O   . LEU D 1 783 ? -46.802 18.395  18.237  1.00 97.29  ? 858  LEU D O   1 
ATOM   14402 C CB  . LEU D 1 783 ? -46.897 21.393  19.550  1.00 87.40  ? 858  LEU D CB  1 
ATOM   14403 C CG  . LEU D 1 783 ? -46.032 20.527  20.474  1.00 83.39  ? 858  LEU D CG  1 
ATOM   14404 C CD1 . LEU D 1 783 ? -44.640 20.305  19.895  1.00 88.28  ? 858  LEU D CD1 1 
ATOM   14405 C CD2 . LEU D 1 783 ? -45.949 21.124  21.869  1.00 95.42  ? 858  LEU D CD2 1 
ATOM   14406 N N   . HIS D 1 784 ? -48.900 19.103  18.641  1.00 86.33  ? 859  HIS D N   1 
ATOM   14407 C CA  . HIS D 1 784 ? -49.398 17.731  18.735  1.00 90.54  ? 859  HIS D CA  1 
ATOM   14408 C C   . HIS D 1 784 ? -49.240 16.989  17.410  1.00 91.01  ? 859  HIS D C   1 
ATOM   14409 O O   . HIS D 1 784 ? -48.832 15.818  17.387  1.00 95.90  ? 859  HIS D O   1 
ATOM   14410 C CB  . HIS D 1 784 ? -50.858 17.720  19.182  1.00 98.22  ? 859  HIS D CB  1 
ATOM   14411 C CG  . HIS D 1 784 ? -51.063 18.172  20.593  1.00 95.42  ? 859  HIS D CG  1 
ATOM   14412 N ND1 . HIS D 1 784 ? -51.750 19.322  20.917  1.00 103.82 ? 859  HIS D ND1 1 
ATOM   14413 C CD2 . HIS D 1 784 ? -50.666 17.627  21.767  1.00 85.81  ? 859  HIS D CD2 1 
ATOM   14414 C CE1 . HIS D 1 784 ? -51.771 19.463  22.231  1.00 99.74  ? 859  HIS D CE1 1 
ATOM   14415 N NE2 . HIS D 1 784 ? -51.119 18.450  22.770  1.00 90.36  ? 859  HIS D NE2 1 
ATOM   14416 N N   . LYS D 1 785 ? -49.564 17.651  16.296  1.00 89.71  ? 860  LYS D N   1 
ATOM   14417 C CA  . LYS D 1 785 ? -49.388 17.000  14.995  1.00 101.43 ? 860  LYS D CA  1 
ATOM   14418 C C   . LYS D 1 785 ? -47.922 16.637  14.752  1.00 100.34 ? 860  LYS D C   1 
ATOM   14419 O O   . LYS D 1 785 ? -47.608 15.527  14.291  1.00 98.11  ? 860  LYS D O   1 
ATOM   14420 C CB  . LYS D 1 785 ? -49.918 17.897  13.874  1.00 105.76 ? 860  LYS D CB  1 
ATOM   14421 C CG  . LYS D 1 785 ? -49.765 17.304  12.475  1.00 122.24 ? 860  LYS D CG  1 
ATOM   14422 C CD  . LYS D 1 785 ? -50.440 15.941  12.358  1.00 124.70 ? 860  LYS D CD  1 
ATOM   14423 C CE  . LYS D 1 785 ? -49.989 15.195  11.107  1.00 110.91 ? 860  LYS D CE  1 
ATOM   14424 N NZ  . LYS D 1 785 ? -50.362 15.913  9.855   1.00 113.06 ? 860  LYS D NZ  1 
ATOM   14425 N N   . ARG D 1 786 ? -47.010 17.560  15.069  1.00 94.92  ? 861  ARG D N   1 
ATOM   14426 C CA  . ARG D 1 786 ? -45.587 17.293  14.867  1.00 91.05  ? 861  ARG D CA  1 
ATOM   14427 C C   . ARG D 1 786 ? -45.103 16.158  15.763  1.00 95.14  ? 861  ARG D C   1 
ATOM   14428 O O   . ARG D 1 786 ? -44.257 15.351  15.353  1.00 86.32  ? 861  ARG D O   1 
ATOM   14429 C CB  . ARG D 1 786 ? -44.775 18.566  15.113  1.00 87.68  ? 861  ARG D CB  1 
ATOM   14430 C CG  . ARG D 1 786 ? -45.117 19.700  14.161  1.00 95.00  ? 861  ARG D CG  1 
ATOM   14431 C CD  . ARG D 1 786 ? -44.242 20.924  14.376  1.00 91.88  ? 861  ARG D CD  1 
ATOM   14432 N NE  . ARG D 1 786 ? -44.068 21.262  15.784  1.00 87.81  ? 861  ARG D NE  1 
ATOM   14433 C CZ  . ARG D 1 786 ? -44.535 22.368  16.348  1.00 104.03 ? 861  ARG D CZ  1 
ATOM   14434 N NH1 . ARG D 1 786 ? -45.264 23.236  15.666  1.00 101.40 ? 861  ARG D NH1 1 
ATOM   14435 N NH2 . ARG D 1 786 ? -44.260 22.610  17.626  1.00 111.55 ? 861  ARG D NH2 1 
ATOM   14436 N N   . ARG D 1 787 ? -45.628 16.085  16.990  1.00 85.97  ? 862  ARG D N   1 
ATOM   14437 C CA  . ARG D 1 787 ? -45.276 14.990  17.887  1.00 73.32  ? 862  ARG D CA  1 
ATOM   14438 C C   . ARG D 1 787 ? -45.748 13.657  17.326  1.00 72.33  ? 862  ARG D C   1 
ATOM   14439 O O   . ARG D 1 787 ? -45.049 12.645  17.439  1.00 71.00  ? 862  ARG D O   1 
ATOM   14440 C CB  . ARG D 1 787 ? -45.875 15.231  19.274  1.00 75.95  ? 862  ARG D CB  1 
ATOM   14441 C CG  . ARG D 1 787 ? -45.201 16.348  20.058  1.00 81.71  ? 862  ARG D CG  1 
ATOM   14442 C CD  . ARG D 1 787 ? -45.730 16.454  21.486  1.00 73.66  ? 862  ARG D CD  1 
ATOM   14443 N NE  . ARG D 1 787 ? -45.302 15.349  22.337  1.00 67.50  ? 862  ARG D NE  1 
ATOM   14444 C CZ  . ARG D 1 787 ? -46.088 14.356  22.729  1.00 87.96  ? 862  ARG D CZ  1 
ATOM   14445 N NH1 . ARG D 1 787 ? -47.358 14.291  22.361  1.00 103.07 ? 862  ARG D NH1 1 
ATOM   14446 N NH2 . ARG D 1 787 ? -45.591 13.407  23.518  1.00 80.46  ? 862  ARG D NH2 1 
ATOM   14447 N N   . ASN D 1 788 ? -46.931 13.642  16.706  1.00 78.96  ? 863  ASN D N   1 
ATOM   14448 C CA  . ASN D 1 788 ? -47.412 12.414  16.078  1.00 78.60  ? 863  ASN D CA  1 
ATOM   14449 C C   . ASN D 1 788 ? -46.498 11.986  14.932  1.00 87.74  ? 863  ASN D C   1 
ATOM   14450 O O   . ASN D 1 788 ? -46.195 10.795  14.776  1.00 87.80  ? 863  ASN D O   1 
ATOM   14451 C CB  . ASN D 1 788 ? -48.847 12.611  15.588  1.00 65.20  ? 863  ASN D CB  1 
ATOM   14452 C CG  . ASN D 1 788 ? -49.362 11.430  14.794  1.00 80.65  ? 863  ASN D CG  1 
ATOM   14453 O OD1 . ASN D 1 788 ? -49.374 10.298  15.279  1.00 91.58  ? 863  ASN D OD1 1 
ATOM   14454 N ND2 . ASN D 1 788 ? -49.804 11.689  13.569  1.00 77.71  ? 863  ASN D ND2 1 
ATOM   14455 N N   . LEU D 1 789 ? -46.047 12.948  14.122  1.00 86.57  ? 864  LEU D N   1 
ATOM   14456 C CA  . LEU D 1 789 ? -45.126 12.635  13.027  1.00 79.66  ? 864  LEU D CA  1 
ATOM   14457 C C   . LEU D 1 789 ? -43.820 12.037  13.555  1.00 82.06  ? 864  LEU D C   1 
ATOM   14458 O O   . LEU D 1 789 ? -43.352 10.977  13.090  1.00 81.47  ? 864  LEU D O   1 
ATOM   14459 C CB  . LEU D 1 789 ? -44.844 13.908  12.227  1.00 86.64  ? 864  LEU D CB  1 
ATOM   14460 C CG  . LEU D 1 789 ? -46.025 14.554  11.498  1.00 82.84  ? 864  LEU D CG  1 
ATOM   14461 C CD1 . LEU D 1 789 ? -45.612 15.876  10.871  1.00 80.12  ? 864  LEU D CD1 1 
ATOM   14462 C CD2 . LEU D 1 789 ? -46.602 13.622  10.445  1.00 88.53  ? 864  LEU D CD2 1 
ATOM   14463 N N   . LEU D 1 790 ? -43.204 12.731  14.519  1.00 70.13  ? 865  LEU D N   1 
ATOM   14464 C CA  . LEU D 1 790 ? -41.978 12.236  15.135  1.00 78.78  ? 865  LEU D CA  1 
ATOM   14465 C C   . LEU D 1 790 ? -42.180 10.850  15.729  1.00 77.26  ? 865  LEU D C   1 
ATOM   14466 O O   . LEU D 1 790 ? -41.296 9.993   15.633  1.00 67.06  ? 865  LEU D O   1 
ATOM   14467 C CB  . LEU D 1 790 ? -41.503 13.203  16.217  1.00 75.75  ? 865  LEU D CB  1 
ATOM   14468 C CG  . LEU D 1 790 ? -40.232 12.734  16.926  1.00 69.28  ? 865  LEU D CG  1 
ATOM   14469 C CD1 . LEU D 1 790 ? -39.021 12.823  16.003  1.00 70.75  ? 865  LEU D CD1 1 
ATOM   14470 C CD2 . LEU D 1 790 ? -40.006 13.505  18.203  1.00 75.73  ? 865  LEU D CD2 1 
ATOM   14471 N N   . ALA D 1 791 ? -43.338 10.612  16.352  1.00 76.39  ? 866  ALA D N   1 
ATOM   14472 C CA  . ALA D 1 791 ? -43.611 9.307   16.938  1.00 73.03  ? 866  ALA D CA  1 
ATOM   14473 C C   . ALA D 1 791 ? -43.747 8.234   15.870  1.00 75.93  ? 866  ALA D C   1 
ATOM   14474 O O   . ALA D 1 791 ? -43.382 7.082   16.110  1.00 61.98  ? 866  ALA D O   1 
ATOM   14475 C CB  . ALA D 1 791 ? -44.873 9.368   17.797  1.00 67.25  ? 866  ALA D CB  1 
ATOM   14476 N N   . ALA D 1 792 ? -44.267 8.586   14.693  1.00 82.34  ? 867  ALA D N   1 
ATOM   14477 C CA  . ALA D 1 792 ? -44.284 7.627   13.592  1.00 76.96  ? 867  ALA D CA  1 
ATOM   14478 C C   . ALA D 1 792 ? -42.869 7.187   13.234  1.00 79.69  ? 867  ALA D C   1 
ATOM   14479 O O   . ALA D 1 792 ? -42.558 5.982   13.201  1.00 83.56  ? 867  ALA D O   1 
ATOM   14480 C CB  . ALA D 1 792 ? -44.989 8.231   12.378  1.00 72.02  ? 867  ALA D CB  1 
ATOM   14481 N N   . PHE D 1 793 ? -41.984 8.157   12.980  1.00 86.28  ? 868  PHE D N   1 
ATOM   14482 C CA  . PHE D 1 793 ? -40.621 7.764   12.612  1.00 79.84  ? 868  PHE D CA  1 
ATOM   14483 C C   . PHE D 1 793 ? -39.918 7.040   13.761  1.00 74.57  ? 868  PHE D C   1 
ATOM   14484 O O   . PHE D 1 793 ? -39.154 6.090   13.535  1.00 75.80  ? 868  PHE D O   1 
ATOM   14485 C CB  . PHE D 1 793 ? -39.795 8.967   12.158  1.00 71.54  ? 868  PHE D CB  1 
ATOM   14486 C CG  . PHE D 1 793 ? -38.488 8.583   11.511  1.00 77.27  ? 868  PHE D CG  1 
ATOM   14487 C CD1 . PHE D 1 793 ? -38.470 7.737   10.411  1.00 90.49  ? 868  PHE D CD1 1 
ATOM   14488 C CD2 . PHE D 1 793 ? -37.281 9.046   12.011  1.00 74.88  ? 868  PHE D CD2 1 
ATOM   14489 C CE1 . PHE D 1 793 ? -37.275 7.370   9.817   1.00 89.23  ? 868  PHE D CE1 1 
ATOM   14490 C CE2 . PHE D 1 793 ? -36.082 8.681   11.420  1.00 80.74  ? 868  PHE D CE2 1 
ATOM   14491 C CZ  . PHE D 1 793 ? -36.081 7.843   10.321  1.00 84.37  ? 868  PHE D CZ  1 
ATOM   14492 N N   . CYS D 1 794 ? -40.185 7.450   15.001  1.00 66.94  ? 869  CYS D N   1 
ATOM   14493 C CA  . CYS D 1 794 ? -39.543 6.815   16.145  1.00 66.78  ? 869  CYS D CA  1 
ATOM   14494 C C   . CYS D 1 794 ? -40.059 5.399   16.362  1.00 76.27  ? 869  CYS D C   1 
ATOM   14495 O O   . CYS D 1 794 ? -39.313 4.535   16.833  1.00 83.77  ? 869  CYS D O   1 
ATOM   14496 C CB  . CYS D 1 794 ? -39.756 7.660   17.401  1.00 69.44  ? 869  CYS D CB  1 
ATOM   14497 S SG  . CYS D 1 794 ? -38.717 9.139   17.495  1.00 67.12  ? 869  CYS D SG  1 
ATOM   14498 N N   . LYS D 1 795 ? -41.331 5.148   16.044  1.00 72.15  ? 870  LYS D N   1 
ATOM   14499 C CA  . LYS D 1 795 ? -41.835 3.781   16.025  1.00 69.78  ? 870  LYS D CA  1 
ATOM   14500 C C   . LYS D 1 795 ? -41.088 2.954   14.994  1.00 77.22  ? 870  LYS D C   1 
ATOM   14501 O O   . LYS D 1 795 ? -40.739 1.796   15.251  1.00 79.00  ? 870  LYS D O   1 
ATOM   14502 C CB  . LYS D 1 795 ? -43.334 3.770   15.721  1.00 61.93  ? 870  LYS D CB  1 
ATOM   14503 C CG  . LYS D 1 795 ? -44.236 4.031   16.911  1.00 65.63  ? 870  LYS D CG  1 
ATOM   14504 C CD  . LYS D 1 795 ? -45.695 4.057   16.480  1.00 68.73  ? 870  LYS D CD  1 
ATOM   14505 C CE  . LYS D 1 795 ? -45.938 5.116   15.421  1.00 70.84  ? 870  LYS D CE  1 
ATOM   14506 N NZ  . LYS D 1 795 ? -47.382 5.298   15.124  1.00 78.67  ? 870  LYS D NZ  1 
ATOM   14507 N N   . LEU D 1 796 ? -40.838 3.531   13.815  1.00 76.86  ? 871  LEU D N   1 
ATOM   14508 C CA  . LEU D 1 796 ? -40.004 2.823   12.844  1.00 77.25  ? 871  LEU D CA  1 
ATOM   14509 C C   . LEU D 1 796 ? -38.637 2.487   13.431  1.00 81.25  ? 871  LEU D C   1 
ATOM   14510 O O   . LEU D 1 796 ? -38.107 1.392   13.204  1.00 79.68  ? 871  LEU D O   1 
ATOM   14511 C CB  . LEU D 1 796 ? -39.848 3.636   11.560  1.00 68.75  ? 871  LEU D CB  1 
ATOM   14512 C CG  . LEU D 1 796 ? -41.127 3.956   10.793  1.00 92.53  ? 871  LEU D CG  1 
ATOM   14513 C CD1 . LEU D 1 796 ? -40.781 4.584   9.454   1.00 85.34  ? 871  LEU D CD1 1 
ATOM   14514 C CD2 . LEU D 1 796 ? -41.965 2.699   10.604  1.00 85.60  ? 871  LEU D CD2 1 
ATOM   14515 N N   . ILE D 1 797 ? -38.055 3.413   14.194  1.00 85.52  ? 872  ILE D N   1 
ATOM   14516 C CA  . ILE D 1 797 ? -36.730 3.168   14.768  1.00 78.46  ? 872  ILE D CA  1 
ATOM   14517 C C   . ILE D 1 797 ? -36.782 2.054   15.813  1.00 75.14  ? 872  ILE D C   1 
ATOM   14518 O O   . ILE D 1 797 ? -36.001 1.096   15.758  1.00 78.84  ? 872  ILE D O   1 
ATOM   14519 C CB  . ILE D 1 797 ? -36.139 4.460   15.359  1.00 66.66  ? 872  ILE D CB  1 
ATOM   14520 C CG1 . ILE D 1 797 ? -36.132 5.579   14.317  1.00 72.28  ? 872  ILE D CG1 1 
ATOM   14521 C CG2 . ILE D 1 797 ? -34.737 4.207   15.894  1.00 68.99  ? 872  ILE D CG2 1 
ATOM   14522 C CD1 . ILE D 1 797 ? -35.674 6.910   14.863  1.00 62.53  ? 872  ILE D CD1 1 
ATOM   14523 N N   . VAL D 1 798 ? -37.695 2.164   16.782  1.00 76.32  ? 873  VAL D N   1 
ATOM   14524 C CA  . VAL D 1 798 ? -37.706 1.246   17.919  1.00 73.20  ? 873  VAL D CA  1 
ATOM   14525 C C   . VAL D 1 798 ? -38.188 -0.147  17.542  1.00 80.75  ? 873  VAL D C   1 
ATOM   14526 O O   . VAL D 1 798 ? -38.005 -1.091  18.318  1.00 80.47  ? 873  VAL D O   1 
ATOM   14527 C CB  . VAL D 1 798 ? -38.574 1.796   19.066  1.00 73.27  ? 873  VAL D CB  1 
ATOM   14528 C CG1 . VAL D 1 798 ? -38.048 3.136   19.541  1.00 69.10  ? 873  VAL D CG1 1 
ATOM   14529 C CG2 . VAL D 1 798 ? -40.025 1.906   18.628  1.00 82.71  ? 873  VAL D CG2 1 
ATOM   14530 N N   . TYR D 1 799 ? -38.823 -0.306  16.382  1.00 86.79  ? 874  TYR D N   1 
ATOM   14531 C CA  . TYR D 1 799 ? -39.262 -1.617  15.926  1.00 92.56  ? 874  TYR D CA  1 
ATOM   14532 C C   . TYR D 1 799 ? -38.419 -2.119  14.760  1.00 97.16  ? 874  TYR D C   1 
ATOM   14533 O O   . TYR D 1 799 ? -38.862 -2.989  14.002  1.00 101.43 ? 874  TYR D O   1 
ATOM   14534 C CB  . TYR D 1 799 ? -40.746 -1.580  15.564  1.00 95.76  ? 874  TYR D CB  1 
ATOM   14535 C CG  . TYR D 1 799 ? -41.630 -1.331  16.767  1.00 99.29  ? 874  TYR D CG  1 
ATOM   14536 C CD1 . TYR D 1 799 ? -41.724 -2.267  17.786  1.00 100.54 ? 874  TYR D CD1 1 
ATOM   14537 C CD2 . TYR D 1 799 ? -42.364 -0.158  16.887  1.00 99.09  ? 874  TYR D CD2 1 
ATOM   14538 C CE1 . TYR D 1 799 ? -42.522 -2.041  18.890  1.00 107.28 ? 874  TYR D CE1 1 
ATOM   14539 C CE2 . TYR D 1 799 ? -43.167 0.075   17.986  1.00 103.82 ? 874  TYR D CE2 1 
ATOM   14540 C CZ  . TYR D 1 799 ? -43.245 -0.872  18.984  1.00 109.74 ? 874  TYR D CZ  1 
ATOM   14541 O OH  . TYR D 1 799 ? -44.043 -0.648  20.082  1.00 104.74 ? 874  TYR D OH  1 
ATOM   14542 N N   . THR D 1 800 ? -37.209 -1.574  14.611  1.00 88.89  ? 875  THR D N   1 
ATOM   14543 C CA  . THR D 1 800 ? -36.200 -2.013  13.647  1.00 83.39  ? 875  THR D CA  1 
ATOM   14544 C C   . THR D 1 800 ? -36.687 -1.944  12.203  1.00 88.45  ? 875  THR D C   1 
ATOM   14545 O O   . THR D 1 800 ? -36.181 -2.669  11.341  1.00 92.84  ? 875  THR D O   1 
ATOM   14546 C CB  . THR D 1 800 ? -35.697 -3.426  13.969  1.00 78.17  ? 875  THR D CB  1 
ATOM   14547 O OG1 . THR D 1 800 ? -36.712 -4.386  13.648  1.00 104.42 ? 875  THR D OG1 1 
ATOM   14548 C CG2 . THR D 1 800 ? -35.344 -3.540  15.445  1.00 74.15  ? 875  THR D CG2 1 
ATOM   14549 N N   . VAL D 1 801 ? -37.655 -1.074  11.911  1.00 86.57  ? 876  VAL D N   1 
ATOM   14550 C CA  . VAL D 1 801 ? -38.076 -0.888  10.526  1.00 79.49  ? 876  VAL D CA  1 
ATOM   14551 C C   . VAL D 1 801 ? -37.022 -0.106  9.754   1.00 77.57  ? 876  VAL D C   1 
ATOM   14552 O O   . VAL D 1 801 ? -36.772 -0.373  8.572   1.00 92.10  ? 876  VAL D O   1 
ATOM   14553 C CB  . VAL D 1 801 ? -39.454 -0.202  10.472  1.00 87.00  ? 876  VAL D CB  1 
ATOM   14554 C CG1 . VAL D 1 801 ? -39.915 -0.044  9.033   1.00 95.62  ? 876  VAL D CG1 1 
ATOM   14555 C CG2 . VAL D 1 801 ? -40.472 -1.004  11.269  1.00 84.20  ? 876  VAL D CG2 1 
ATOM   14556 N N   . VAL D 1 802 ? -36.380 0.861   10.408  1.00 73.74  ? 877  VAL D N   1 
ATOM   14557 C CA  . VAL D 1 802 ? -35.306 1.642   9.813   1.00 85.89  ? 877  VAL D CA  1 
ATOM   14558 C C   . VAL D 1 802 ? -34.034 1.421   10.624  1.00 97.53  ? 877  VAL D C   1 
ATOM   14559 O O   . VAL D 1 802 ? -34.056 0.864   11.721  1.00 101.31 ? 877  VAL D O   1 
ATOM   14560 C CB  . VAL D 1 802 ? -35.644 3.142   9.732   1.00 80.67  ? 877  VAL D CB  1 
ATOM   14561 C CG1 . VAL D 1 802 ? -36.840 3.370   8.819   1.00 77.88  ? 877  VAL D CG1 1 
ATOM   14562 C CG2 . VAL D 1 802 ? -35.908 3.695   11.120  1.00 84.10  ? 877  VAL D CG2 1 
ATOM   14563 N N   . GLU D 1 803 ? -32.917 1.876   10.063  1.00 100.61 ? 878  GLU D N   1 
ATOM   14564 C CA  . GLU D 1 803 ? -31.625 1.719   10.714  1.00 108.86 ? 878  GLU D CA  1 
ATOM   14565 C C   . GLU D 1 803 ? -31.537 2.603   11.956  1.00 98.63  ? 878  GLU D C   1 
ATOM   14566 O O   . GLU D 1 803 ? -32.101 3.699   12.007  1.00 93.04  ? 878  GLU D O   1 
ATOM   14567 C CB  . GLU D 1 803 ? -30.495 2.066   9.741   1.00 125.26 ? 878  GLU D CB  1 
ATOM   14568 C CG  . GLU D 1 803 ? -30.412 1.192   8.483   1.00 120.24 ? 878  GLU D CG  1 
ATOM   14569 C CD  . GLU D 1 803 ? -29.933 -0.232  8.744   1.00 126.61 ? 878  GLU D CD  1 
ATOM   14570 O OE1 . GLU D 1 803 ? -29.937 -0.683  9.909   1.00 129.02 ? 878  GLU D OE1 1 
ATOM   14571 O OE2 . GLU D 1 803 ? -29.540 -0.905  7.767   1.00 129.38 ? 878  GLU D OE2 1 
ATOM   14572 N N   . MET D 1 804 ? -30.814 2.112   12.967  1.00 95.25  ? 879  MET D N   1 
ATOM   14573 C CA  . MET D 1 804 ? -30.667 2.873   14.205  1.00 94.41  ? 879  MET D CA  1 
ATOM   14574 C C   . MET D 1 804 ? -29.893 4.169   14.000  1.00 103.17 ? 879  MET D C   1 
ATOM   14575 O O   . MET D 1 804 ? -30.130 5.146   14.723  1.00 100.81 ? 879  MET D O   1 
ATOM   14576 C CB  . MET D 1 804 ? -29.981 2.025   15.274  1.00 84.10  ? 879  MET D CB  1 
ATOM   14577 C CG  . MET D 1 804 ? -30.931 1.360   16.247  1.00 102.07 ? 879  MET D CG  1 
ATOM   14578 S SD  . MET D 1 804 ? -30.046 0.280   17.384  1.00 130.72 ? 879  MET D SD  1 
ATOM   14579 C CE  . MET D 1 804 ? -29.726 1.413   18.726  1.00 79.23  ? 879  MET D CE  1 
ATOM   14580 N N   . ASN D 1 805 ? -28.975 4.203   13.029  1.00 101.79 ? 880  ASN D N   1 
ATOM   14581 C CA  . ASN D 1 805 ? -28.142 5.388   12.834  1.00 102.14 ? 880  ASN D CA  1 
ATOM   14582 C C   . ASN D 1 805 ? -28.976 6.637   12.576  1.00 105.48 ? 880  ASN D C   1 
ATOM   14583 O O   . ASN D 1 805 ? -28.606 7.730   13.022  1.00 105.74 ? 880  ASN D O   1 
ATOM   14584 C CB  . ASN D 1 805 ? -27.151 5.147   11.690  1.00 115.94 ? 880  ASN D CB  1 
ATOM   14585 C CG  . ASN D 1 805 ? -27.761 5.393   10.320  1.00 137.84 ? 880  ASN D CG  1 
ATOM   14586 O OD1 . ASN D 1 805 ? -28.714 4.721   9.925   1.00 154.22 ? 880  ASN D OD1 1 
ATOM   14587 N ND2 . ASN D 1 805 ? -27.214 6.360   9.590   1.00 152.69 ? 880  ASN D ND2 1 
ATOM   14588 N N   . THR D 1 806 ? -30.108 6.490   11.883  1.00 103.86 ? 881  THR D N   1 
ATOM   14589 C CA  . THR D 1 806 ? -31.014 7.614   11.673  1.00 100.26 ? 881  THR D CA  1 
ATOM   14590 C C   . THR D 1 806 ? -31.345 8.301   12.990  1.00 102.23 ? 881  THR D C   1 
ATOM   14591 O O   . THR D 1 806 ? -31.255 9.531   13.105  1.00 106.49 ? 881  THR D O   1 
ATOM   14592 C CB  . THR D 1 806 ? -32.293 7.128   10.992  1.00 90.14  ? 881  THR D CB  1 
ATOM   14593 O OG1 . THR D 1 806 ? -32.993 6.251   11.882  1.00 98.28  ? 881  THR D OG1 1 
ATOM   14594 C CG2 . THR D 1 806 ? -31.952 6.365   9.729   1.00 99.60  ? 881  THR D CG2 1 
ATOM   14595 N N   . ALA D 1 807 ? -31.690 7.505   14.011  1.00 94.44  ? 882  ALA D N   1 
ATOM   14596 C CA  . ALA D 1 807 ? -32.063 8.047   15.312  1.00 98.11  ? 882  ALA D CA  1 
ATOM   14597 C C   . ALA D 1 807 ? -31.044 9.038   15.852  1.00 95.16  ? 882  ALA D C   1 
ATOM   14598 O O   . ALA D 1 807 ? -31.406 9.876   16.687  1.00 94.21  ? 882  ALA D O   1 
ATOM   14599 C CB  . ALA D 1 807 ? -32.256 6.915   16.323  1.00 95.21  ? 882  ALA D CB  1 
ATOM   14600 N N   . ALA D 1 808 ? -29.786 8.966   15.400  1.00 83.52  ? 883  ALA D N   1 
ATOM   14601 C CA  . ALA D 1 808 ? -28.796 9.957   15.807  1.00 87.16  ? 883  ALA D CA  1 
ATOM   14602 C C   . ALA D 1 808 ? -29.359 11.367  15.688  1.00 93.68  ? 883  ALA D C   1 
ATOM   14603 O O   . ALA D 1 808 ? -29.403 12.115  16.673  1.00 101.82 ? 883  ALA D O   1 
ATOM   14604 C CB  . ALA D 1 808 ? -27.523 9.810   14.970  1.00 92.08  ? 883  ALA D CB  1 
ATOM   14605 N N   . ASP D 1 809 ? -29.859 11.724  14.501  1.00 92.25  ? 884  ASP D N   1 
ATOM   14606 C CA  . ASP D 1 809 ? -30.337 13.088  14.291  1.00 92.33  ? 884  ASP D CA  1 
ATOM   14607 C C   . ASP D 1 809 ? -31.504 13.431  15.207  1.00 90.84  ? 884  ASP D C   1 
ATOM   14608 O O   . ASP D 1 809 ? -31.683 14.600  15.567  1.00 94.50  ? 884  ASP D O   1 
ATOM   14609 C CB  . ASP D 1 809 ? -30.725 13.296  12.830  1.00 94.20  ? 884  ASP D CB  1 
ATOM   14610 C CG  . ASP D 1 809 ? -29.581 13.015  11.890  1.00 102.12 ? 884  ASP D CG  1 
ATOM   14611 O OD1 . ASP D 1 809 ? -28.475 12.719  12.390  1.00 117.99 ? 884  ASP D OD1 1 
ATOM   14612 O OD2 . ASP D 1 809 ? -29.772 13.114  10.662  1.00 102.63 ? 884  ASP D OD2 1 
ATOM   14613 N N   . ILE D 1 810 ? -32.303 12.439  15.602  1.00 80.92  ? 885  ILE D N   1 
ATOM   14614 C CA  . ILE D 1 810 ? -33.345 12.700  16.589  1.00 80.98  ? 885  ILE D CA  1 
ATOM   14615 C C   . ILE D 1 810 ? -32.729 12.860  17.974  1.00 87.38  ? 885  ILE D C   1 
ATOM   14616 O O   . ILE D 1 810 ? -33.043 13.808  18.705  1.00 89.45  ? 885  ILE D O   1 
ATOM   14617 C CB  . ILE D 1 810 ? -34.414 11.591  16.569  1.00 81.35  ? 885  ILE D CB  1 
ATOM   14618 C CG1 . ILE D 1 810 ? -35.174 11.586  15.241  1.00 59.82  ? 885  ILE D CG1 1 
ATOM   14619 C CG2 . ILE D 1 810 ? -35.386 11.777  17.723  1.00 87.31  ? 885  ILE D CG2 1 
ATOM   14620 C CD1 . ILE D 1 810 ? -34.627 10.619  14.223  1.00 72.31  ? 885  ILE D CD1 1 
ATOM   14621 N N   . PHE D 1 811 ? -31.822 11.949  18.344  1.00 81.32  ? 886  PHE D N   1 
ATOM   14622 C CA  . PHE D 1 811 ? -31.242 11.989  19.684  1.00 78.80  ? 886  PHE D CA  1 
ATOM   14623 C C   . PHE D 1 811 ? -30.466 13.278  19.914  1.00 85.42  ? 886  PHE D C   1 
ATOM   14624 O O   . PHE D 1 811 ? -30.370 13.753  21.051  1.00 86.04  ? 886  PHE D O   1 
ATOM   14625 C CB  . PHE D 1 811 ? -30.327 10.783  19.904  1.00 70.48  ? 886  PHE D CB  1 
ATOM   14626 C CG  . PHE D 1 811 ? -31.045 9.460   19.926  1.00 76.02  ? 886  PHE D CG  1 
ATOM   14627 C CD1 . PHE D 1 811 ? -32.430 9.394   19.873  1.00 91.08  ? 886  PHE D CD1 1 
ATOM   14628 C CD2 . PHE D 1 811 ? -30.328 8.281   20.009  1.00 75.09  ? 886  PHE D CD2 1 
ATOM   14629 C CE1 . PHE D 1 811 ? -33.080 8.174   19.890  1.00 92.51  ? 886  PHE D CE1 1 
ATOM   14630 C CE2 . PHE D 1 811 ? -30.971 7.061   20.032  1.00 77.66  ? 886  PHE D CE2 1 
ATOM   14631 C CZ  . PHE D 1 811 ? -32.350 7.006   19.973  1.00 83.69  ? 886  PHE D CZ  1 
ATOM   14632 N N   . LYS D 1 812 ? -29.910 13.854  18.846  1.00 92.24  ? 887  LYS D N   1 
ATOM   14633 C CA  . LYS D 1 812 ? -29.205 15.126  18.952  1.00 86.92  ? 887  LYS D CA  1 
ATOM   14634 C C   . LYS D 1 812 ? -30.116 16.237  19.461  1.00 81.15  ? 887  LYS D C   1 
ATOM   14635 O O   . LYS D 1 812 ? -29.663 17.127  20.190  1.00 80.36  ? 887  LYS D O   1 
ATOM   14636 C CB  . LYS D 1 812 ? -28.617 15.488  17.588  1.00 90.84  ? 887  LYS D CB  1 
ATOM   14637 C CG  . LYS D 1 812 ? -28.225 16.944  17.412  1.00 99.14  ? 887  LYS D CG  1 
ATOM   14638 C CD  . LYS D 1 812 ? -28.233 17.336  15.941  1.00 106.69 ? 887  LYS D CD  1 
ATOM   14639 C CE  . LYS D 1 812 ? -27.690 16.217  15.068  1.00 104.92 ? 887  LYS D CE  1 
ATOM   14640 N NZ  . LYS D 1 812 ? -27.782 16.539  13.618  1.00 116.70 ? 887  LYS D NZ  1 
ATOM   14641 N N   . GLN D 1 813 ? -31.401 16.196  19.107  1.00 85.82  ? 888  GLN D N   1 
ATOM   14642 C CA  . GLN D 1 813 ? -32.342 17.244  19.478  1.00 99.43  ? 888  GLN D CA  1 
ATOM   14643 C C   . GLN D 1 813 ? -33.038 16.963  20.806  1.00 92.18  ? 888  GLN D C   1 
ATOM   14644 O O   . GLN D 1 813 ? -34.064 17.588  21.103  1.00 95.69  ? 888  GLN D O   1 
ATOM   14645 C CB  . GLN D 1 813 ? -33.374 17.438  18.366  1.00 96.73  ? 888  GLN D CB  1 
ATOM   14646 C CG  . GLN D 1 813 ? -32.772 17.689  16.984  1.00 88.09  ? 888  GLN D CG  1 
ATOM   14647 C CD  . GLN D 1 813 ? -32.203 19.091  16.827  1.00 100.13 ? 888  GLN D CD  1 
ATOM   14648 O OE1 . GLN D 1 813 ? -31.248 19.468  17.507  1.00 107.81 ? 888  GLN D OE1 1 
ATOM   14649 N NE2 . GLN D 1 813 ? -32.787 19.868  15.921  1.00 104.31 ? 888  GLN D NE2 1 
ATOM   14650 N N   . TYR D 1 814 ? -32.495 16.044  21.610  1.00 82.24  ? 889  TYR D N   1 
ATOM   14651 C CA  . TYR D 1 814 ? -33.127 15.673  22.873  1.00 91.20  ? 889  TYR D CA  1 
ATOM   14652 C C   . TYR D 1 814 ? -33.234 16.870  23.812  1.00 95.73  ? 889  TYR D C   1 
ATOM   14653 O O   . TYR D 1 814 ? -34.319 17.186  24.312  1.00 102.66 ? 889  TYR D O   1 
ATOM   14654 C CB  . TYR D 1 814 ? -32.342 14.532  23.524  1.00 98.90  ? 889  TYR D CB  1 
ATOM   14655 C CG  . TYR D 1 814 ? -32.799 14.159  24.916  1.00 94.97  ? 889  TYR D CG  1 
ATOM   14656 C CD1 . TYR D 1 814 ? -34.122 13.821  25.173  1.00 94.09  ? 889  TYR D CD1 1 
ATOM   14657 C CD2 . TYR D 1 814 ? -31.900 14.128  25.973  1.00 96.15  ? 889  TYR D CD2 1 
ATOM   14658 C CE1 . TYR D 1 814 ? -34.537 13.474  26.448  1.00 101.63 ? 889  TYR D CE1 1 
ATOM   14659 C CE2 . TYR D 1 814 ? -32.304 13.783  27.246  1.00 100.09 ? 889  TYR D CE2 1 
ATOM   14660 C CZ  . TYR D 1 814 ? -33.621 13.457  27.480  1.00 95.76  ? 889  TYR D CZ  1 
ATOM   14661 O OH  . TYR D 1 814 ? -34.015 13.114  28.753  1.00 93.44  ? 889  TYR D OH  1 
ATOM   14662 N N   . MET D 1 815 ? -32.114 17.554  24.059  1.00 91.01  ? 890  MET D N   1 
ATOM   14663 C CA  . MET D 1 815 ? -32.151 18.717  24.940  1.00 104.79 ? 890  MET D CA  1 
ATOM   14664 C C   . MET D 1 815 ? -32.769 19.930  24.257  1.00 99.66  ? 890  MET D C   1 
ATOM   14665 O O   . MET D 1 815 ? -33.413 20.751  24.922  1.00 92.39  ? 890  MET D O   1 
ATOM   14666 C CB  . MET D 1 815 ? -30.745 19.056  25.434  1.00 112.45 ? 890  MET D CB  1 
ATOM   14667 C CG  . MET D 1 815 ? -30.474 18.635  26.864  1.00 124.25 ? 890  MET D CG  1 
ATOM   14668 S SD  . MET D 1 815 ? -28.835 19.140  27.409  1.00 163.15 ? 890  MET D SD  1 
ATOM   14669 C CE  . MET D 1 815 ? -29.232 20.685  28.222  1.00 158.27 ? 890  MET D CE  1 
ATOM   14670 N N   . LYS D 1 816 ? -32.583 20.064  22.941  1.00 94.72  ? 891  LYS D N   1 
ATOM   14671 C CA  . LYS D 1 816 ? -33.107 21.229  22.236  1.00 92.69  ? 891  LYS D CA  1 
ATOM   14672 C C   . LYS D 1 816 ? -34.627 21.291  22.321  1.00 96.88  ? 891  LYS D C   1 
ATOM   14673 O O   . LYS D 1 816 ? -35.201 22.368  22.512  1.00 103.22 ? 891  LYS D O   1 
ATOM   14674 C CB  . LYS D 1 816 ? -32.652 21.207  20.777  1.00 101.50 ? 891  LYS D CB  1 
ATOM   14675 C CG  . LYS D 1 816 ? -32.922 22.497  20.023  1.00 115.77 ? 891  LYS D CG  1 
ATOM   14676 C CD  . LYS D 1 816 ? -32.357 22.445  18.613  1.00 111.94 ? 891  LYS D CD  1 
ATOM   14677 C CE  . LYS D 1 816 ? -32.732 23.688  17.823  1.00 105.73 ? 891  LYS D CE  1 
ATOM   14678 N NZ  . LYS D 1 816 ? -32.311 23.599  16.398  1.00 96.17  ? 891  LYS D NZ  1 
ATOM   14679 N N   . TYR D 1 817 ? -35.294 20.146  22.186  1.00 101.35 ? 892  TYR D N   1 
ATOM   14680 C CA  . TYR D 1 817 ? -36.749 20.105  22.260  1.00 100.51 ? 892  TYR D CA  1 
ATOM   14681 C C   . TYR D 1 817 ? -37.216 19.191  23.385  1.00 93.84  ? 892  TYR D C   1 
ATOM   14682 O O   . TYR D 1 817 ? -38.085 18.342  23.166  1.00 101.70 ? 892  TYR D O   1 
ATOM   14683 C CB  . TYR D 1 817 ? -37.357 19.614  20.944  1.00 100.85 ? 892  TYR D CB  1 
ATOM   14684 C CG  . TYR D 1 817 ? -36.929 20.355  19.698  1.00 104.65 ? 892  TYR D CG  1 
ATOM   14685 C CD1 . TYR D 1 817 ? -35.731 20.054  19.064  1.00 96.12  ? 892  TYR D CD1 1 
ATOM   14686 C CD2 . TYR D 1 817 ? -37.736 21.339  19.140  1.00 106.92 ? 892  TYR D CD2 1 
ATOM   14687 C CE1 . TYR D 1 817 ? -35.343 20.719  17.918  1.00 98.77  ? 892  TYR D CE1 1 
ATOM   14688 C CE2 . TYR D 1 817 ? -37.355 22.010  17.994  1.00 101.64 ? 892  TYR D CE2 1 
ATOM   14689 C CZ  . TYR D 1 817 ? -36.158 21.697  17.388  1.00 101.90 ? 892  TYR D CZ  1 
ATOM   14690 O OH  . TYR D 1 817 ? -35.775 22.363  16.246  1.00 107.14 ? 892  TYR D OH  1 
ATOM   14691 N N   . TYR D 1 818 ? -36.649 19.343  24.586  1.00 87.91  ? 893  TYR D N   1 
ATOM   14692 C CA  . TYR D 1 818 ? -37.034 18.460  25.682  1.00 97.74  ? 893  TYR D CA  1 
ATOM   14693 C C   . TYR D 1 818 ? -38.515 18.615  26.008  1.00 108.21 ? 893  TYR D C   1 
ATOM   14694 O O   . TYR D 1 818 ? -39.228 17.620  26.178  1.00 109.59 ? 893  TYR D O   1 
ATOM   14695 C CB  . TYR D 1 818 ? -36.173 18.731  26.916  1.00 101.64 ? 893  TYR D CB  1 
ATOM   14696 C CG  . TYR D 1 818 ? -36.368 17.728  28.037  1.00 109.23 ? 893  TYR D CG  1 
ATOM   14697 C CD1 . TYR D 1 818 ? -36.124 16.375  27.833  1.00 110.34 ? 893  TYR D CD1 1 
ATOM   14698 C CD2 . TYR D 1 818 ? -36.786 18.133  29.299  1.00 102.68 ? 893  TYR D CD2 1 
ATOM   14699 C CE1 . TYR D 1 818 ? -36.296 15.453  28.852  1.00 112.27 ? 893  TYR D CE1 1 
ATOM   14700 C CE2 . TYR D 1 818 ? -36.960 17.218  30.326  1.00 100.62 ? 893  TYR D CE2 1 
ATOM   14701 C CZ  . TYR D 1 818 ? -36.713 15.881  30.096  1.00 112.24 ? 893  TYR D CZ  1 
ATOM   14702 O OH  . TYR D 1 818 ? -36.885 14.968  31.112  1.00 107.12 ? 893  TYR D OH  1 
ATOM   14703 N N   . ASN D 1 819 ? -39.007 19.852  26.037  1.00 111.34 ? 894  ASN D N   1 
ATOM   14704 C CA  . ASN D 1 819 ? -40.425 20.077  26.292  1.00 101.55 ? 894  ASN D CA  1 
ATOM   14705 C C   . ASN D 1 819 ? -41.283 19.630  25.111  1.00 90.98  ? 894  ASN D C   1 
ATOM   14706 O O   . ASN D 1 819 ? -42.313 18.973  25.297  1.00 107.52 ? 894  ASN D O   1 
ATOM   14707 C CB  . ASN D 1 819 ? -40.667 21.550  26.615  1.00 103.01 ? 894  ASN D CB  1 
ATOM   14708 C CG  . ASN D 1 819 ? -39.736 22.472  25.855  1.00 121.57 ? 894  ASN D CG  1 
ATOM   14709 O OD1 . ASN D 1 819 ? -39.611 22.379  24.633  1.00 124.16 ? 894  ASN D OD1 1 
ATOM   14710 N ND2 . ASN D 1 819 ? -39.072 23.367  26.576  1.00 117.03 ? 894  ASN D ND2 1 
ATOM   14711 N N   . ASP D 1 820 ? -40.875 19.971  23.885  1.00 95.82  ? 895  ASP D N   1 
ATOM   14712 C CA  . ASP D 1 820 ? -41.702 19.663  22.720  1.00 86.31  ? 895  ASP D CA  1 
ATOM   14713 C C   . ASP D 1 820 ? -41.709 18.169  22.410  1.00 83.21  ? 895  ASP D C   1 
ATOM   14714 O O   . ASP D 1 820 ? -42.775 17.569  22.228  1.00 90.13  ? 895  ASP D O   1 
ATOM   14715 C CB  . ASP D 1 820 ? -41.226 20.460  21.505  1.00 86.82  ? 895  ASP D CB  1 
ATOM   14716 C CG  . ASP D 1 820 ? -41.497 21.945  21.640  1.00 91.73  ? 895  ASP D CG  1 
ATOM   14717 O OD1 . ASP D 1 820 ? -41.975 22.371  22.712  1.00 91.53  ? 895  ASP D OD1 1 
ATOM   14718 O OD2 . ASP D 1 820 ? -41.241 22.686  20.668  1.00 97.29  ? 895  ASP D OD2 1 
ATOM   14719 N N   . TYR D 1 821 ? -40.529 17.547  22.336  1.00 78.80  ? 896  TYR D N   1 
ATOM   14720 C CA  . TYR D 1 821 ? -40.429 16.159  21.898  1.00 86.35  ? 896  TYR D CA  1 
ATOM   14721 C C   . TYR D 1 821 ? -39.567 15.285  22.805  1.00 78.70  ? 896  TYR D C   1 
ATOM   14722 O O   . TYR D 1 821 ? -39.285 14.132  22.441  1.00 87.61  ? 896  TYR D O   1 
ATOM   14723 C CB  . TYR D 1 821 ? -39.875 16.084  20.470  1.00 92.88  ? 896  TYR D CB  1 
ATOM   14724 C CG  . TYR D 1 821 ? -40.450 17.082  19.488  1.00 92.86  ? 896  TYR D CG  1 
ATOM   14725 C CD1 . TYR D 1 821 ? -41.780 17.016  19.099  1.00 90.41  ? 896  TYR D CD1 1 
ATOM   14726 C CD2 . TYR D 1 821 ? -39.652 18.066  18.924  1.00 88.39  ? 896  TYR D CD2 1 
ATOM   14727 C CE1 . TYR D 1 821 ? -42.304 17.920  18.192  1.00 93.19  ? 896  TYR D CE1 1 
ATOM   14728 C CE2 . TYR D 1 821 ? -40.166 18.973  18.017  1.00 83.90  ? 896  TYR D CE2 1 
ATOM   14729 C CZ  . TYR D 1 821 ? -41.491 18.896  17.654  1.00 89.81  ? 896  TYR D CZ  1 
ATOM   14730 O OH  . TYR D 1 821 ? -42.005 19.798  16.750  1.00 95.98  ? 896  TYR D OH  1 
ATOM   14731 N N   . GLY D 1 822 ? -39.138 15.794  23.964  1.00 70.90  ? 897  GLY D N   1 
ATOM   14732 C CA  . GLY D 1 822 ? -38.171 15.073  24.770  1.00 85.51  ? 897  GLY D CA  1 
ATOM   14733 C C   . GLY D 1 822 ? -38.683 13.748  25.292  1.00 91.60  ? 897  GLY D C   1 
ATOM   14734 O O   . GLY D 1 822 ? -37.910 12.803  25.444  1.00 81.83  ? 897  GLY D O   1 
ATOM   14735 N N   . ASP D 1 823 ? -39.986 13.652  25.564  1.00 87.37  ? 898  ASP D N   1 
ATOM   14736 C CA  . ASP D 1 823 ? -40.544 12.384  26.023  1.00 77.17  ? 898  ASP D CA  1 
ATOM   14737 C C   . ASP D 1 823 ? -40.453 11.312  24.939  1.00 78.04  ? 898  ASP D C   1 
ATOM   14738 O O   . ASP D 1 823 ? -40.033 10.178  25.207  1.00 82.64  ? 898  ASP D O   1 
ATOM   14739 C CB  . ASP D 1 823 ? -41.986 12.588  26.496  1.00 89.25  ? 898  ASP D CB  1 
ATOM   14740 C CG  . ASP D 1 823 ? -42.854 13.288  25.465  1.00 90.11  ? 898  ASP D CG  1 
ATOM   14741 O OD1 . ASP D 1 823 ? -42.670 13.051  24.256  1.00 93.68  ? 898  ASP D OD1 1 
ATOM   14742 O OD2 . ASP D 1 823 ? -43.734 14.075  25.870  1.00 105.82 ? 898  ASP D OD2 1 
ATOM   14743 N N   . ILE D 1 824 ? -40.836 11.655  23.706  1.00 84.12  ? 899  ILE D N   1 
ATOM   14744 C CA  . ILE D 1 824 ? -40.702 10.717  22.592  1.00 83.93  ? 899  ILE D CA  1 
ATOM   14745 C C   . ILE D 1 824 ? -39.241 10.331  22.394  1.00 88.53  ? 899  ILE D C   1 
ATOM   14746 O O   . ILE D 1 824 ? -38.913 9.155   22.191  1.00 79.44  ? 899  ILE D O   1 
ATOM   14747 C CB  . ILE D 1 824 ? -41.303 11.316  21.307  1.00 74.41  ? 899  ILE D CB  1 
ATOM   14748 C CG1 . ILE D 1 824 ? -42.759 11.727  21.527  1.00 66.31  ? 899  ILE D CG1 1 
ATOM   14749 C CG2 . ILE D 1 824 ? -41.186 10.333  20.150  1.00 75.39  ? 899  ILE D CG2 1 
ATOM   14750 C CD1 . ILE D 1 824 ? -43.352 12.502  20.377  1.00 75.59  ? 899  ILE D CD1 1 
ATOM   14751 N N   . ILE D 1 825 ? -38.342 11.316  22.451  1.00 83.36  ? 900  ILE D N   1 
ATOM   14752 C CA  . ILE D 1 825 ? -36.929 11.028  22.211  1.00 79.75  ? 900  ILE D CA  1 
ATOM   14753 C C   . ILE D 1 825 ? -36.370 10.126  23.307  1.00 79.89  ? 900  ILE D C   1 
ATOM   14754 O O   . ILE D 1 825 ? -35.596 9.201   23.033  1.00 86.93  ? 900  ILE D O   1 
ATOM   14755 C CB  . ILE D 1 825 ? -36.125 12.336  22.077  1.00 78.19  ? 900  ILE D CB  1 
ATOM   14756 C CG1 . ILE D 1 825 ? -36.710 13.209  20.963  1.00 75.74  ? 900  ILE D CG1 1 
ATOM   14757 C CG2 . ILE D 1 825 ? -34.659 12.032  21.805  1.00 83.79  ? 900  ILE D CG2 1 
ATOM   14758 C CD1 . ILE D 1 825 ? -36.013 14.541  20.800  1.00 72.54  ? 900  ILE D CD1 1 
ATOM   14759 N N   . LYS D 1 826 ? -36.770 10.363  24.557  1.00 75.38  ? 901  LYS D N   1 
ATOM   14760 C CA  . LYS D 1 826 ? -36.300 9.545   25.670  1.00 78.11  ? 901  LYS D CA  1 
ATOM   14761 C C   . LYS D 1 826 ? -36.810 8.116   25.561  1.00 75.73  ? 901  LYS D C   1 
ATOM   14762 O O   . LYS D 1 826 ? -36.055 7.159   25.786  1.00 86.42  ? 901  LYS D O   1 
ATOM   14763 C CB  . LYS D 1 826 ? -36.744 10.172  26.991  1.00 83.78  ? 901  LYS D CB  1 
ATOM   14764 C CG  . LYS D 1 826 ? -36.088 9.584   28.227  1.00 93.57  ? 901  LYS D CG  1 
ATOM   14765 C CD  . LYS D 1 826 ? -36.754 10.087  29.501  1.00 116.50 ? 901  LYS D CD  1 
ATOM   14766 C CE  . LYS D 1 826 ? -36.837 11.608  29.534  1.00 123.00 ? 901  LYS D CE  1 
ATOM   14767 N NZ  . LYS D 1 826 ? -37.418 12.105  30.813  1.00 123.15 ? 901  LYS D NZ  1 
ATOM   14768 N N   . GLU D 1 827 ? -38.093 7.951   25.228  1.00 80.39  ? 902  GLU D N   1 
ATOM   14769 C CA  . GLU D 1 827 ? -38.638 6.610   25.057  1.00 86.44  ? 902  GLU D CA  1 
ATOM   14770 C C   . GLU D 1 827 ? -37.936 5.874   23.924  1.00 90.86  ? 902  GLU D C   1 
ATOM   14771 O O   . GLU D 1 827 ? -37.620 4.681   24.045  1.00 89.92  ? 902  GLU D O   1 
ATOM   14772 C CB  . GLU D 1 827 ? -40.143 6.689   24.804  1.00 75.45  ? 902  GLU D CB  1 
ATOM   14773 C CG  . GLU D 1 827 ? -40.843 5.345   24.701  1.00 69.64  ? 902  GLU D CG  1 
ATOM   14774 C CD  . GLU D 1 827 ? -41.010 4.664   26.047  1.00 80.27  ? 902  GLU D CD  1 
ATOM   14775 O OE1 . GLU D 1 827 ? -40.530 5.209   27.064  1.00 79.05  ? 902  GLU D OE1 1 
ATOM   14776 O OE2 . GLU D 1 827 ? -41.640 3.587   26.089  1.00 87.59  ? 902  GLU D OE2 1 
ATOM   14777 N N   . THR D 1 828 ? -37.684 6.573   22.812  1.00 90.70  ? 903  THR D N   1 
ATOM   14778 C CA  . THR D 1 828 ? -36.943 5.975   21.706  1.00 89.82  ? 903  THR D CA  1 
ATOM   14779 C C   . THR D 1 828 ? -35.548 5.554   22.144  1.00 86.78  ? 903  THR D C   1 
ATOM   14780 O O   . THR D 1 828 ? -35.081 4.464   21.796  1.00 90.13  ? 903  THR D O   1 
ATOM   14781 C CB  . THR D 1 828 ? -36.857 6.960   20.539  1.00 77.97  ? 903  THR D CB  1 
ATOM   14782 O OG1 . THR D 1 828 ? -38.147 7.536   20.301  1.00 79.20  ? 903  THR D OG1 1 
ATOM   14783 C CG2 . THR D 1 828 ? -36.366 6.262   19.280  1.00 70.27  ? 903  THR D CG2 1 
ATOM   14784 N N   . MET D 1 829 ? -34.866 6.411   22.906  1.00 77.45  ? 904  MET D N   1 
ATOM   14785 C CA  . MET D 1 829 ? -33.528 6.085   23.387  1.00 77.31  ? 904  MET D CA  1 
ATOM   14786 C C   . MET D 1 829 ? -33.550 4.824   24.239  1.00 82.81  ? 904  MET D C   1 
ATOM   14787 O O   . MET D 1 829 ? -32.718 3.927   24.064  1.00 92.29  ? 904  MET D O   1 
ATOM   14788 C CB  . MET D 1 829 ? -32.963 7.261   24.183  1.00 79.99  ? 904  MET D CB  1 
ATOM   14789 C CG  . MET D 1 829 ? -32.249 8.304   23.340  1.00 83.69  ? 904  MET D CG  1 
ATOM   14790 S SD  . MET D 1 829 ? -31.493 9.613   24.327  1.00 100.62 ? 904  MET D SD  1 
ATOM   14791 C CE  . MET D 1 829 ? -32.664 9.757   25.675  1.00 84.19  ? 904  MET D CE  1 
ATOM   14792 N N   . SER D 1 830 ? -34.507 4.738   25.163  1.00 92.51  ? 905  SER D N   1 
ATOM   14793 C CA  . SER D 1 830 ? -34.580 3.580   26.050  1.00 89.04  ? 905  SER D CA  1 
ATOM   14794 C C   . SER D 1 830 ? -34.870 2.301   25.270  1.00 84.62  ? 905  SER D C   1 
ATOM   14795 O O   . SER D 1 830 ? -34.222 1.266   25.486  1.00 86.17  ? 905  SER D O   1 
ATOM   14796 C CB  . SER D 1 830 ? -35.641 3.814   27.124  1.00 87.96  ? 905  SER D CB  1 
ATOM   14797 O OG  . SER D 1 830 ? -35.380 5.011   27.837  1.00 105.37 ? 905  SER D OG  1 
ATOM   14798 N N   . LYS D 1 831 ? -35.841 2.352   24.353  1.00 89.01  ? 906  LYS D N   1 
ATOM   14799 C CA  . LYS D 1 831 ? -36.167 1.164   23.569  1.00 88.93  ? 906  LYS D CA  1 
ATOM   14800 C C   . LYS D 1 831 ? -34.986 0.723   22.711  1.00 91.80  ? 906  LYS D C   1 
ATOM   14801 O O   . LYS D 1 831 ? -34.670 -0.472  22.646  1.00 94.27  ? 906  LYS D O   1 
ATOM   14802 C CB  . LYS D 1 831 ? -37.397 1.420   22.700  1.00 74.00  ? 906  LYS D CB  1 
ATOM   14803 C CG  . LYS D 1 831 ? -38.679 1.644   23.484  1.00 88.96  ? 906  LYS D CG  1 
ATOM   14804 C CD  . LYS D 1 831 ? -38.868 0.590   24.566  1.00 100.89 ? 906  LYS D CD  1 
ATOM   14805 C CE  . LYS D 1 831 ? -39.864 1.059   25.616  1.00 107.90 ? 906  LYS D CE  1 
ATOM   14806 N NZ  . LYS D 1 831 ? -39.435 0.763   27.013  1.00 103.00 ? 906  LYS D NZ  1 
ATOM   14807 N N   . THR D 1 832 ? -34.315 1.673   22.052  1.00 84.25  ? 907  THR D N   1 
ATOM   14808 C CA  . THR D 1 832 ? -33.156 1.329   21.235  1.00 82.50  ? 907  THR D CA  1 
ATOM   14809 C C   . THR D 1 832 ? -32.033 0.747   22.083  1.00 103.73 ? 907  THR D C   1 
ATOM   14810 O O   . THR D 1 832 ? -31.337 -0.179  21.650  1.00 145.45 ? 907  THR D O   1 
ATOM   14811 C CB  . THR D 1 832 ? -32.665 2.558   20.473  1.00 86.92  ? 907  THR D CB  1 
ATOM   14812 O OG1 . THR D 1 832 ? -32.424 3.629   21.395  1.00 95.28  ? 907  THR D OG1 1 
ATOM   14813 C CG2 . THR D 1 832 ? -33.688 2.991   19.435  1.00 88.56  ? 907  THR D CG2 1 
ATOM   14814 N N   . ARG D 1 833 ? -31.833 1.282   23.290  1.00 101.94 ? 908  ARG D N   1 
ATOM   14815 C CA  . ARG D 1 833 ? -30.837 0.714   24.190  1.00 94.57  ? 908  ARG D CA  1 
ATOM   14816 C C   . ARG D 1 833 ? -31.177 -0.729  24.533  1.00 96.79  ? 908  ARG D C   1 
ATOM   14817 O O   . ARG D 1 833 ? -30.291 -1.591  24.571  1.00 99.39  ? 908  ARG D O   1 
ATOM   14818 C CB  . ARG D 1 833 ? -30.732 1.558   25.459  1.00 100.96 ? 908  ARG D CB  1 
ATOM   14819 C CG  . ARG D 1 833 ? -29.559 1.200   26.357  1.00 109.20 ? 908  ARG D CG  1 
ATOM   14820 C CD  . ARG D 1 833 ? -29.252 2.338   27.314  1.00 127.36 ? 908  ARG D CD  1 
ATOM   14821 N NE  . ARG D 1 833 ? -30.452 3.112   27.610  1.00 128.52 ? 908  ARG D NE  1 
ATOM   14822 C CZ  . ARG D 1 833 ? -31.119 3.054   28.755  1.00 128.26 ? 908  ARG D CZ  1 
ATOM   14823 N NH1 . ARG D 1 833 ? -30.728 2.267   29.744  1.00 150.99 ? 908  ARG D NH1 1 
ATOM   14824 N NH2 . ARG D 1 833 ? -32.208 3.802   28.910  1.00 113.62 ? 908  ARG D NH2 1 
ATOM   14825 N N   . GLN D 1 834 ? -32.459 -1.015  24.781  1.00 103.04 ? 909  GLN D N   1 
ATOM   14826 C CA  . GLN D 1 834 ? -32.860 -2.402  25.004  1.00 103.30 ? 909  GLN D CA  1 
ATOM   14827 C C   . GLN D 1 834 ? -32.574 -3.265  23.780  1.00 97.96  ? 909  GLN D C   1 
ATOM   14828 O O   . GLN D 1 834 ? -32.145 -4.417  23.912  1.00 94.09  ? 909  GLN D O   1 
ATOM   14829 C CB  . GLN D 1 834 ? -34.339 -2.489  25.374  1.00 99.56  ? 909  GLN D CB  1 
ATOM   14830 C CG  . GLN D 1 834 ? -34.717 -1.774  26.653  1.00 106.68 ? 909  GLN D CG  1 
ATOM   14831 C CD  . GLN D 1 834 ? -36.210 -1.554  26.761  1.00 130.82 ? 909  GLN D CD  1 
ATOM   14832 O OE1 . GLN D 1 834 ? -36.671 -0.430  26.960  1.00 139.54 ? 909  GLN D OE1 1 
ATOM   14833 N NE2 . GLN D 1 834 ? -36.977 -2.629  26.626  1.00 152.52 ? 909  GLN D NE2 1 
ATOM   14834 N N   . ILE D 1 835 ? -32.806 -2.726  22.581  1.00 101.23 ? 910  ILE D N   1 
ATOM   14835 C CA  . ILE D 1 835 ? -32.561 -3.491  21.359  1.00 104.97 ? 910  ILE D CA  1 
ATOM   14836 C C   . ILE D 1 835 ? -31.080 -3.828  21.230  1.00 106.33 ? 910  ILE D C   1 
ATOM   14837 O O   . ILE D 1 835 ? -30.697 -4.996  21.097  1.00 111.84 ? 910  ILE D O   1 
ATOM   14838 C CB  . ILE D 1 835 ? -33.065 -2.722  20.127  1.00 106.93 ? 910  ILE D CB  1 
ATOM   14839 C CG1 . ILE D 1 835 ? -34.557 -2.423  20.258  1.00 83.10  ? 910  ILE D CG1 1 
ATOM   14840 C CG2 . ILE D 1 835 ? -32.780 -3.510  18.857  1.00 94.68  ? 910  ILE D CG2 1 
ATOM   14841 C CD1 . ILE D 1 835 ? -35.038 -1.376  19.293  1.00 87.15  ? 910  ILE D CD1 1 
ATOM   14842 N N   . ASP D 1 836 ? -30.225 -2.806  21.260  1.00 108.63 ? 911  ASP D N   1 
ATOM   14843 C CA  . ASP D 1 836 ? -28.786 -3.013  21.098  1.00 115.44 ? 911  ASP D CA  1 
ATOM   14844 C C   . ASP D 1 836 ? -28.070 -1.921  21.888  1.00 114.63 ? 911  ASP D C   1 
ATOM   14845 O O   . ASP D 1 836 ? -27.924 -0.795  21.403  1.00 104.70 ? 911  ASP D O   1 
ATOM   14846 C CB  . ASP D 1 836 ? -28.392 -2.999  19.627  1.00 110.49 ? 911  ASP D CB  1 
ATOM   14847 C CG  . ASP D 1 836 ? -27.099 -3.740  19.368  1.00 115.33 ? 911  ASP D CG  1 
ATOM   14848 O OD1 . ASP D 1 836 ? -26.576 -4.360  20.316  1.00 108.71 ? 911  ASP D OD1 1 
ATOM   14849 O OD2 . ASP D 1 836 ? -26.611 -3.710  18.218  1.00 121.52 ? 911  ASP D OD2 1 
ATOM   14850 N N   . LYS D 1 837 ? -27.628 -2.269  23.099  1.00 108.73 ? 912  LYS D N   1 
ATOM   14851 C CA  . LYS D 1 837 ? -26.969 -1.304  23.976  1.00 100.90 ? 912  LYS D CA  1 
ATOM   14852 C C   . LYS D 1 837 ? -25.727 -0.713  23.317  1.00 108.65 ? 912  LYS D C   1 
ATOM   14853 O O   . LYS D 1 837 ? -25.515 0.507   23.334  1.00 106.10 ? 912  LYS D O   1 
ATOM   14854 C CB  . LYS D 1 837 ? -26.608 -1.984  25.299  1.00 95.21  ? 912  LYS D CB  1 
ATOM   14855 C CG  . LYS D 1 837 ? -27.696 -2.907  25.839  1.00 97.84  ? 912  LYS D CG  1 
ATOM   14856 C CD  . LYS D 1 837 ? -27.357 -3.449  27.222  1.00 102.80 ? 912  LYS D CD  1 
ATOM   14857 C CE  . LYS D 1 837 ? -27.061 -2.345  28.218  1.00 98.95  ? 912  LYS D CE  1 
ATOM   14858 N NZ  . LYS D 1 837 ? -28.182 -1.377  28.359  1.00 102.60 ? 912  LYS D NZ  1 
ATOM   14859 N N   . ILE D 1 838 ? -24.894 -1.568  22.724  1.00 102.27 ? 913  ILE D N   1 
ATOM   14860 C CA  . ILE D 1 838 ? -23.640 -1.114  22.128  1.00 96.49  ? 913  ILE D CA  1 
ATOM   14861 C C   . ILE D 1 838 ? -23.910 -0.211  20.927  1.00 101.13 ? 913  ILE D C   1 
ATOM   14862 O O   . ILE D 1 838 ? -23.313 0.867   20.786  1.00 97.13  ? 913  ILE D O   1 
ATOM   14863 C CB  . ILE D 1 838 ? -22.772 -2.333  21.763  1.00 80.28  ? 913  ILE D CB  1 
ATOM   14864 C CG1 . ILE D 1 838 ? -21.525 -1.923  20.979  1.00 98.79  ? 913  ILE D CG1 1 
ATOM   14865 C CG2 . ILE D 1 838 ? -23.590 -3.387  21.022  1.00 93.68  ? 913  ILE D CG2 1 
ATOM   14866 C CD1 . ILE D 1 838 ? -20.505 -3.038  20.863  1.00 114.35 ? 913  ILE D CD1 1 
ATOM   14867 N N   . GLN D 1 839 ? -24.834 -0.620  20.056  1.00 99.95  ? 914  GLN D N   1 
ATOM   14868 C CA  . GLN D 1 839 ? -25.151 0.203   18.895  1.00 101.70 ? 914  GLN D CA  1 
ATOM   14869 C C   . GLN D 1 839 ? -25.859 1.486   19.304  1.00 104.80 ? 914  GLN D C   1 
ATOM   14870 O O   . GLN D 1 839 ? -25.704 2.517   18.641  1.00 96.23  ? 914  GLN D O   1 
ATOM   14871 C CB  . GLN D 1 839 ? -26.003 -0.589  17.906  1.00 100.68 ? 914  GLN D CB  1 
ATOM   14872 C CG  . GLN D 1 839 ? -26.128 0.056   16.535  1.00 100.10 ? 914  GLN D CG  1 
ATOM   14873 C CD  . GLN D 1 839 ? -26.771 -0.870  15.520  1.00 117.54 ? 914  GLN D CD  1 
ATOM   14874 O OE1 . GLN D 1 839 ? -27.833 -0.573  14.975  1.00 127.67 ? 914  GLN D OE1 1 
ATOM   14875 N NE2 . GLN D 1 839 ? -26.128 -2.004  15.264  1.00 128.99 ? 914  GLN D NE2 1 
ATOM   14876 N N   . CYS D 1 840 ? -26.626 1.452   20.395  1.00 93.74  ? 915  CYS D N   1 
ATOM   14877 C CA  . CYS D 1 840 ? -27.231 2.680   20.898  1.00 98.64  ? 915  CYS D CA  1 
ATOM   14878 C C   . CYS D 1 840 ? -26.166 3.642   21.409  1.00 101.88 ? 915  CYS D C   1 
ATOM   14879 O O   . CYS D 1 840 ? -26.264 4.859   21.203  1.00 100.30 ? 915  CYS D O   1 
ATOM   14880 C CB  . CYS D 1 840 ? -28.240 2.356   21.997  1.00 105.99 ? 915  CYS D CB  1 
ATOM   14881 S SG  . CYS D 1 840 ? -29.145 3.793   22.605  1.00 97.34  ? 915  CYS D SG  1 
ATOM   14882 N N   . ALA D 1 841 ? -25.141 3.113   22.082  1.00 102.23 ? 916  ALA D N   1 
ATOM   14883 C CA  . ALA D 1 841 ? -24.003 3.943   22.459  1.00 100.84 ? 916  ALA D CA  1 
ATOM   14884 C C   . ALA D 1 841 ? -23.351 4.561   21.229  1.00 95.86  ? 916  ALA D C   1 
ATOM   14885 O O   . ALA D 1 841 ? -22.967 5.739   21.239  1.00 90.66  ? 916  ALA D O   1 
ATOM   14886 C CB  . ALA D 1 841 ? -22.990 3.114   23.249  1.00 97.30  ? 916  ALA D CB  1 
ATOM   14887 N N   . LYS D 1 842 ? -23.224 3.779   20.153  1.00 94.03  ? 917  LYS D N   1 
ATOM   14888 C CA  . LYS D 1 842 ? -22.621 4.317   18.936  1.00 97.12  ? 917  LYS D CA  1 
ATOM   14889 C C   . LYS D 1 842 ? -23.484 5.418   18.323  1.00 101.36 ? 917  LYS D C   1 
ATOM   14890 O O   . LYS D 1 842 ? -22.964 6.439   17.865  1.00 101.29 ? 917  LYS D O   1 
ATOM   14891 C CB  . LYS D 1 842 ? -22.352 3.199   17.926  1.00 91.24  ? 917  LYS D CB  1 
ATOM   14892 C CG  . LYS D 1 842 ? -21.502 2.062   18.477  1.00 86.03  ? 917  LYS D CG  1 
ATOM   14893 C CD  . LYS D 1 842 ? -20.874 1.247   17.361  1.00 100.00 ? 917  LYS D CD  1 
ATOM   14894 C CE  . LYS D 1 842 ? -20.058 2.139   16.435  1.00 109.16 ? 917  LYS D CE  1 
ATOM   14895 N NZ  . LYS D 1 842 ? -19.271 1.335   15.464  1.00 111.64 ? 917  LYS D NZ  1 
ATOM   14896 N N   . THR D 1 843 ? -24.805 5.247   18.323  1.00 96.01  ? 918  THR D N   1 
ATOM   14897 C CA  . THR D 1 843 ? -25.667 6.292   17.768  1.00 99.89  ? 918  THR D CA  1 
ATOM   14898 C C   . THR D 1 843 ? -25.641 7.555   18.624  1.00 101.61 ? 918  THR D C   1 
ATOM   14899 O O   . THR D 1 843 ? -25.712 8.674   18.098  1.00 97.73  ? 918  THR D O   1 
ATOM   14900 C CB  . THR D 1 843 ? -27.095 5.777   17.622  1.00 95.02  ? 918  THR D CB  1 
ATOM   14901 O OG1 . THR D 1 843 ? -27.636 5.504   18.922  1.00 113.60 ? 918  THR D OG1 1 
ATOM   14902 C CG2 . THR D 1 843 ? -27.129 4.521   16.754  1.00 91.87  ? 918  THR D CG2 1 
ATOM   14903 N N   . LEU D 1 844 ? -25.530 7.399   19.945  1.00 100.11 ? 919  LEU D N   1 
ATOM   14904 C CA  . LEU D 1 844 ? -25.403 8.567   20.812  1.00 92.08  ? 919  LEU D CA  1 
ATOM   14905 C C   . LEU D 1 844 ? -24.092 9.301   20.556  1.00 106.74 ? 919  LEU D C   1 
ATOM   14906 O O   . LEU D 1 844 ? -24.057 10.541  20.504  1.00 107.87 ? 919  LEU D O   1 
ATOM   14907 C CB  . LEU D 1 844 ? -25.507 8.145   22.277  1.00 83.70  ? 919  LEU D CB  1 
ATOM   14908 C CG  . LEU D 1 844 ? -26.900 7.772   22.790  1.00 88.93  ? 919  LEU D CG  1 
ATOM   14909 C CD1 . LEU D 1 844 ? -26.853 7.393   24.261  1.00 97.76  ? 919  LEU D CD1 1 
ATOM   14910 C CD2 . LEU D 1 844 ? -27.888 8.903   22.561  1.00 91.93  ? 919  LEU D CD2 1 
ATOM   14911 N N   . ILE D 1 845 ? -22.998 8.550   20.394  1.00 109.11 ? 920  ILE D N   1 
ATOM   14912 C CA  . ILE D 1 845 ? -21.723 9.192   20.099  1.00 109.38 ? 920  ILE D CA  1 
ATOM   14913 C C   . ILE D 1 845 ? -21.790 9.863   18.737  1.00 116.27 ? 920  ILE D C   1 
ATOM   14914 O O   . ILE D 1 845 ? -21.169 10.906  18.521  1.00 114.04 ? 920  ILE D O   1 
ATOM   14915 C CB  . ILE D 1 845 ? -20.558 8.182   20.190  1.00 108.20 ? 920  ILE D CB  1 
ATOM   14916 C CG1 . ILE D 1 845 ? -19.236 8.921   20.357  1.00 113.04 ? 920  ILE D CG1 1 
ATOM   14917 C CG2 . ILE D 1 845 ? -20.467 7.308   18.943  1.00 120.12 ? 920  ILE D CG2 1 
ATOM   14918 C CD1 . ILE D 1 845 ? -19.235 9.869   21.520  1.00 107.91 ? 920  ILE D CD1 1 
ATOM   14919 N N   . LEU D 1 846 ? -22.574 9.305   17.812  1.00 117.09 ? 921  LEU D N   1 
ATOM   14920 C CA  . LEU D 1 846 ? -22.752 9.960   16.521  1.00 105.67 ? 921  LEU D CA  1 
ATOM   14921 C C   . LEU D 1 846 ? -23.495 11.279  16.669  1.00 100.02 ? 921  LEU D C   1 
ATOM   14922 O O   . LEU D 1 846 ? -23.142 12.269  16.022  1.00 106.65 ? 921  LEU D O   1 
ATOM   14923 C CB  . LEU D 1 846 ? -23.493 9.049   15.540  1.00 107.77 ? 921  LEU D CB  1 
ATOM   14924 C CG  . LEU D 1 846 ? -22.768 7.807   15.026  1.00 102.64 ? 921  LEU D CG  1 
ATOM   14925 C CD1 . LEU D 1 846 ? -23.753 6.828   14.408  1.00 106.77 ? 921  LEU D CD1 1 
ATOM   14926 C CD2 . LEU D 1 846 ? -21.703 8.207   14.027  1.00 109.16 ? 921  LEU D CD2 1 
ATOM   14927 N N   . SER D 1 847 ? -24.539 11.310  17.500  1.00 107.96 ? 922  SER D N   1 
ATOM   14928 C CA  . SER D 1 847 ? -25.248 12.566  17.739  1.00 113.20 ? 922  SER D CA  1 
ATOM   14929 C C   . SER D 1 847 ? -24.307 13.622  18.316  1.00 105.98 ? 922  SER D C   1 
ATOM   14930 O O   . SER D 1 847 ? -24.294 14.781  17.872  1.00 102.09 ? 922  SER D O   1 
ATOM   14931 C CB  . SER D 1 847 ? -26.439 12.330  18.671  1.00 101.49 ? 922  SER D CB  1 
ATOM   14932 O OG  . SER D 1 847 ? -27.104 11.116  18.364  1.00 95.18  ? 922  SER D OG  1 
ATOM   14933 N N   . LEU D 1 848 ? -23.497 13.233  19.305  1.00 105.08 ? 923  LEU D N   1 
ATOM   14934 C CA  . LEU D 1 848 ? -22.556 14.187  19.890  1.00 100.66 ? 923  LEU D CA  1 
ATOM   14935 C C   . LEU D 1 848 ? -21.510 14.636  18.873  1.00 106.47 ? 923  LEU D C   1 
ATOM   14936 O O   . LEU D 1 848 ? -21.124 15.812  18.844  1.00 106.56 ? 923  LEU D O   1 
ATOM   14937 C CB  . LEU D 1 848 ? -21.889 13.583  21.123  1.00 97.68  ? 923  LEU D CB  1 
ATOM   14938 C CG  . LEU D 1 848 ? -22.815 13.331  22.310  1.00 93.46  ? 923  LEU D CG  1 
ATOM   14939 C CD1 . LEU D 1 848 ? -22.013 12.777  23.460  1.00 93.77  ? 923  LEU D CD1 1 
ATOM   14940 C CD2 . LEU D 1 848 ? -23.520 14.616  22.718  1.00 91.04  ? 923  LEU D CD2 1 
ATOM   14941 N N   . GLN D 1 849 ? -21.041 13.713  18.027  1.00 105.61 ? 924  GLN D N   1 
ATOM   14942 C CA  . GLN D 1 849 ? -20.085 14.062  16.981  1.00 101.57 ? 924  GLN D CA  1 
ATOM   14943 C C   . GLN D 1 849 ? -20.693 15.038  15.985  1.00 118.40 ? 924  GLN D C   1 
ATOM   14944 O O   . GLN D 1 849 ? -20.011 15.944  15.494  1.00 123.41 ? 924  GLN D O   1 
ATOM   14945 C CB  . GLN D 1 849 ? -19.623 12.796  16.258  1.00 96.18  ? 924  GLN D CB  1 
ATOM   14946 C CG  . GLN D 1 849 ? -18.697 11.903  17.059  1.00 105.12 ? 924  GLN D CG  1 
ATOM   14947 C CD  . GLN D 1 849 ? -18.323 10.645  16.301  1.00 110.27 ? 924  GLN D CD  1 
ATOM   14948 O OE1 . GLN D 1 849 ? -18.778 10.425  15.179  1.00 108.86 ? 924  GLN D OE1 1 
ATOM   14949 N NE2 . GLN D 1 849 ? -17.506 9.801   16.919  1.00 106.31 ? 924  GLN D NE2 1 
ATOM   14950 N N   . GLN D 1 850 ? -21.974 14.850  15.659  1.00 117.89 ? 925  GLN D N   1 
ATOM   14951 C CA  . GLN D 1 850 ? -22.662 15.761  14.752  1.00 120.43 ? 925  GLN D CA  1 
ATOM   14952 C C   . GLN D 1 850 ? -22.761 17.152  15.361  1.00 122.50 ? 925  GLN D C   1 
ATOM   14953 O O   . GLN D 1 850 ? -22.561 18.159  14.671  1.00 130.84 ? 925  GLN D O   1 
ATOM   14954 C CB  . GLN D 1 850 ? -24.052 15.212  14.426  1.00 113.66 ? 925  GLN D CB  1 
ATOM   14955 C CG  . GLN D 1 850 ? -24.027 13.919  13.622  1.00 122.50 ? 925  GLN D CG  1 
ATOM   14956 C CD  . GLN D 1 850 ? -25.300 13.673  12.842  1.00 141.25 ? 925  GLN D CD  1 
ATOM   14957 O OE1 . GLN D 1 850 ? -26.234 14.472  12.883  1.00 146.49 ? 925  GLN D OE1 1 
ATOM   14958 N NE2 . GLN D 1 850 ? -25.354 12.545  12.143  1.00 151.91 ? 925  GLN D NE2 1 
ATOM   14959 N N   . LEU D 1 851 ? -23.055 17.226  16.661  1.00 112.91 ? 926  LEU D N   1 
ATOM   14960 C CA  . LEU D 1 851 ? -23.071 18.526  17.329  1.00 113.30 ? 926  LEU D CA  1 
ATOM   14961 C C   . LEU D 1 851 ? -21.691 19.179  17.322  1.00 119.29 ? 926  LEU D C   1 
ATOM   14962 O O   . LEU D 1 851 ? -21.571 20.389  17.102  1.00 121.34 ? 926  LEU D O   1 
ATOM   14963 C CB  . LEU D 1 851 ? -23.594 18.384  18.756  1.00 119.12 ? 926  LEU D CB  1 
ATOM   14964 C CG  . LEU D 1 851 ? -25.087 18.093  18.869  1.00 98.19  ? 926  LEU D CG  1 
ATOM   14965 C CD1 . LEU D 1 851 ? -25.425 17.634  20.268  1.00 83.52  ? 926  LEU D CD1 1 
ATOM   14966 C CD2 . LEU D 1 851 ? -25.867 19.347  18.515  1.00 94.61  ? 926  LEU D CD2 1 
ATOM   14967 N N   . PHE D 1 852 ? -20.637 18.392  17.559  1.00 117.52 ? 927  PHE D N   1 
ATOM   14968 C CA  . PHE D 1 852 ? -19.278 18.935  17.537  1.00 121.78 ? 927  PHE D CA  1 
ATOM   14969 C C   . PHE D 1 852 ? -18.906 19.445  16.149  1.00 126.51 ? 927  PHE D C   1 
ATOM   14970 O O   . PHE D 1 852 ? -18.262 20.496  16.008  1.00 130.97 ? 927  PHE D O   1 
ATOM   14971 C CB  . PHE D 1 852 ? -18.289 17.862  17.989  1.00 121.93 ? 927  PHE D CB  1 
ATOM   14972 C CG  . PHE D 1 852 ? -16.925 18.392  18.318  1.00 122.55 ? 927  PHE D CG  1 
ATOM   14973 C CD1 . PHE D 1 852 ? -16.742 19.281  19.362  1.00 126.60 ? 927  PHE D CD1 1 
ATOM   14974 C CD2 . PHE D 1 852 ? -15.823 18.000  17.576  1.00 126.19 ? 927  PHE D CD2 1 
ATOM   14975 C CE1 . PHE D 1 852 ? -15.484 19.765  19.665  1.00 137.10 ? 927  PHE D CE1 1 
ATOM   14976 C CE2 . PHE D 1 852 ? -14.563 18.481  17.871  1.00 130.08 ? 927  PHE D CE2 1 
ATOM   14977 C CZ  . PHE D 1 852 ? -14.392 19.366  18.917  1.00 140.05 ? 927  PHE D CZ  1 
ATOM   14978 N N   . ASN D 1 853 ? -19.280 18.693  15.114  1.00 121.92 ? 928  ASN D N   1 
ATOM   14979 C CA  . ASN D 1 853 ? -19.017 19.113  13.744  1.00 121.14 ? 928  ASN D CA  1 
ATOM   14980 C C   . ASN D 1 853 ? -19.766 20.396  13.414  1.00 122.61 ? 928  ASN D C   1 
ATOM   14981 O O   . ASN D 1 853 ? -19.211 21.303  12.784  1.00 130.49 ? 928  ASN D O   1 
ATOM   14982 C CB  . ASN D 1 853 ? -19.404 17.990  12.784  1.00 120.91 ? 928  ASN D CB  1 
ATOM   14983 C CG  . ASN D 1 853 ? -19.538 18.465  11.356  1.00 161.40 ? 928  ASN D CG  1 
ATOM   14984 O OD1 . ASN D 1 853 ? -20.619 18.408  10.771  1.00 172.63 ? 928  ASN D OD1 1 
ATOM   14985 N ND2 . ASN D 1 853 ? -18.436 18.933  10.782  1.00 174.07 ? 928  ASN D ND2 1 
ATOM   14986 N N   . GLU D 1 854 ? -21.026 20.495  13.844  1.00 113.13 ? 929  GLU D N   1 
ATOM   14987 C CA  . GLU D 1 854 ? -21.780 21.730  13.652  1.00 116.23 ? 929  GLU D CA  1 
ATOM   14988 C C   . GLU D 1 854 ? -21.113 22.897  14.371  1.00 120.41 ? 929  GLU D C   1 
ATOM   14989 O O   . GLU D 1 854 ? -21.067 24.018  13.848  1.00 133.49 ? 929  GLU D O   1 
ATOM   14990 C CB  . GLU D 1 854 ? -23.214 21.543  14.149  1.00 124.95 ? 929  GLU D CB  1 
ATOM   14991 C CG  . GLU D 1 854 ? -24.062 20.619  13.290  1.00 134.15 ? 929  GLU D CG  1 
ATOM   14992 C CD  . GLU D 1 854 ? -25.352 20.214  13.978  1.00 128.75 ? 929  GLU D CD  1 
ATOM   14993 O OE1 . GLU D 1 854 ? -25.276 19.627  15.077  1.00 121.10 ? 929  GLU D OE1 1 
ATOM   14994 O OE2 . GLU D 1 854 ? -26.440 20.482  13.423  1.00 135.54 ? 929  GLU D OE2 1 
ATOM   14995 N N   . MET D 1 855 ? -20.595 22.650  15.576  1.00 124.23 ? 930  MET D N   1 
ATOM   14996 C CA  . MET D 1 855 ? -19.861 23.677  16.309  1.00 131.46 ? 930  MET D CA  1 
ATOM   14997 C C   . MET D 1 855 ? -18.670 24.188  15.514  1.00 129.65 ? 930  MET D C   1 
ATOM   14998 O O   . MET D 1 855 ? -18.561 25.387  15.233  1.00 129.92 ? 930  MET D O   1 
ATOM   14999 C CB  . MET D 1 855 ? -19.394 23.131  17.655  1.00 132.09 ? 930  MET D CB  1 
ATOM   15000 C CG  . MET D 1 855 ? -18.624 24.146  18.468  1.00 142.64 ? 930  MET D CG  1 
ATOM   15001 S SD  . MET D 1 855 ? -18.470 23.631  20.174  1.00 159.71 ? 930  MET D SD  1 
ATOM   15002 C CE  . MET D 1 855 ? -20.154 23.908  20.674  1.00 133.03 ? 930  MET D CE  1 
ATOM   15003 N N   . ILE D 1 856 ? -17.753 23.288  15.155  1.00 135.09 ? 931  ILE D N   1 
ATOM   15004 C CA  . ILE D 1 856 ? -16.563 23.719  14.424  1.00 141.32 ? 931  ILE D CA  1 
ATOM   15005 C C   . ILE D 1 856 ? -16.930 24.295  13.063  1.00 138.80 ? 931  ILE D C   1 
ATOM   15006 O O   . ILE D 1 856 ? -16.148 25.048  12.474  1.00 146.11 ? 931  ILE D O   1 
ATOM   15007 C CB  . ILE D 1 856 ? -15.553 22.561  14.284  1.00 136.61 ? 931  ILE D CB  1 
ATOM   15008 C CG1 . ILE D 1 856 ? -16.104 21.471  13.364  1.00 126.66 ? 931  ILE D CG1 1 
ATOM   15009 C CG2 . ILE D 1 856 ? -15.200 21.997  15.655  1.00 132.21 ? 931  ILE D CG2 1 
ATOM   15010 C CD1 . ILE D 1 856 ? -15.354 20.160  13.453  1.00 119.61 ? 931  ILE D CD1 1 
ATOM   15011 N N   . GLN D 1 857 ? -18.120 23.967  12.553  1.00 136.89 ? 932  GLN D N   1 
ATOM   15012 C CA  . GLN D 1 857 ? -18.583 24.548  11.298  1.00 138.11 ? 932  GLN D CA  1 
ATOM   15013 C C   . GLN D 1 857 ? -19.039 25.990  11.486  1.00 133.19 ? 932  GLN D C   1 
ATOM   15014 O O   . GLN D 1 857 ? -18.778 26.845  10.632  1.00 143.96 ? 932  GLN D O   1 
ATOM   15015 C CB  . GLN D 1 857 ? -19.712 23.686  10.734  1.00 142.14 ? 932  GLN D CB  1 
ATOM   15016 C CG  . GLN D 1 857 ? -20.406 24.240  9.506   1.00 148.50 ? 932  GLN D CG  1 
ATOM   15017 C CD  . GLN D 1 857 ? -21.655 23.452  9.158   1.00 153.47 ? 932  GLN D CD  1 
ATOM   15018 O OE1 . GLN D 1 857 ? -21.898 22.378  9.712   1.00 143.14 ? 932  GLN D OE1 1 
ATOM   15019 N NE2 . GLN D 1 857 ? -22.459 23.984  8.244   1.00 161.50 ? 932  GLN D NE2 1 
ATOM   15020 N N   . GLU D 1 858 ? -19.718 26.280  12.596  1.00 130.54 ? 933  GLU D N   1 
ATOM   15021 C CA  . GLU D 1 858 ? -20.252 27.618  12.839  1.00 133.50 ? 933  GLU D CA  1 
ATOM   15022 C C   . GLU D 1 858 ? -19.279 28.488  13.631  1.00 140.92 ? 933  GLU D C   1 
ATOM   15023 O O   . GLU D 1 858 ? -18.885 29.565  13.172  1.00 141.57 ? 933  GLU D O   1 
ATOM   15024 C CB  . GLU D 1 858 ? -21.600 27.518  13.561  1.00 136.21 ? 933  GLU D CB  1 
ATOM   15025 C CG  . GLU D 1 858 ? -22.691 26.871  12.732  1.00 138.09 ? 933  GLU D CG  1 
ATOM   15026 C CD  . GLU D 1 858 ? -22.813 27.495  11.357  1.00 157.60 ? 933  GLU D CD  1 
ATOM   15027 O OE1 . GLU D 1 858 ? -23.092 28.709  11.281  1.00 159.29 ? 933  GLU D OE1 1 
ATOM   15028 O OE2 . GLU D 1 858 ? -22.630 26.775  10.353  1.00 170.58 ? 933  GLU D OE2 1 
ATOM   15029 N N   . ASN D 1 859 ? -18.892 28.039  14.827  1.00 147.22 ? 934  ASN D N   1 
ATOM   15030 C CA  . ASN D 1 859 ? -17.991 28.832  15.658  1.00 154.42 ? 934  ASN D CA  1 
ATOM   15031 C C   . ASN D 1 859 ? -16.559 28.811  15.147  1.00 153.82 ? 934  ASN D C   1 
ATOM   15032 O O   . ASN D 1 859 ? -15.847 29.811  15.279  1.00 151.34 ? 934  ASN D O   1 
ATOM   15033 C CB  . ASN D 1 859 ? -18.026 28.328  17.101  1.00 154.43 ? 934  ASN D CB  1 
ATOM   15034 C CG  . ASN D 1 859 ? -19.434 28.226  17.648  1.00 146.14 ? 934  ASN D CG  1 
ATOM   15035 O OD1 . ASN D 1 859 ? -19.892 27.150  18.035  1.00 140.17 ? 934  ASN D OD1 1 
ATOM   15036 N ND2 . ASN D 1 859 ? -20.134 29.351  17.676  1.00 146.15 ? 934  ASN D ND2 1 
ATOM   15037 N N   . GLY D 1 860 ? -16.127 27.704  14.564  1.00 156.60 ? 935  GLY D N   1 
ATOM   15038 C CA  . GLY D 1 860 ? -14.758 27.537  14.124  1.00 146.46 ? 935  GLY D CA  1 
ATOM   15039 C C   . GLY D 1 860 ? -13.988 26.590  15.029  1.00 154.18 ? 935  GLY D C   1 
ATOM   15040 O O   . GLY D 1 860 ? -14.420 26.225  16.124  1.00 172.62 ? 935  GLY D O   1 
ATOM   15041 N N   . TYR D 1 861 ? -12.813 26.189  14.540  1.00 148.70 ? 936  TYR D N   1 
ATOM   15042 C CA  . TYR D 1 861 ? -11.953 25.316  15.329  1.00 145.59 ? 936  TYR D CA  1 
ATOM   15043 C C   . TYR D 1 861 ? -11.370 26.016  16.549  1.00 147.26 ? 936  TYR D C   1 
ATOM   15044 O O   . TYR D 1 861 ? -10.855 25.339  17.446  1.00 139.66 ? 936  TYR D O   1 
ATOM   15045 C CB  . TYR D 1 861 ? -10.826 24.760  14.459  1.00 126.42 ? 936  TYR D CB  1 
ATOM   15046 C CG  . TYR D 1 861 ? -11.126 23.397  13.884  1.00 131.33 ? 936  TYR D CG  1 
ATOM   15047 C CD1 . TYR D 1 861 ? -11.396 22.319  14.715  1.00 139.91 ? 936  TYR D CD1 1 
ATOM   15048 C CD2 . TYR D 1 861 ? -11.134 23.186  12.512  1.00 135.53 ? 936  TYR D CD2 1 
ATOM   15049 C CE1 . TYR D 1 861 ? -11.672 21.070  14.195  1.00 149.51 ? 936  TYR D CE1 1 
ATOM   15050 C CE2 . TYR D 1 861 ? -11.405 21.941  11.982  1.00 142.61 ? 936  TYR D CE2 1 
ATOM   15051 C CZ  . TYR D 1 861 ? -11.673 20.886  12.828  1.00 146.61 ? 936  TYR D CZ  1 
ATOM   15052 O OH  . TYR D 1 861 ? -11.945 19.642  12.305  1.00 140.48 ? 936  TYR D OH  1 
ATOM   15053 N N   . ASN D 1 862 ? -11.436 27.346  16.603  1.00 147.13 ? 937  ASN D N   1 
ATOM   15054 C CA  . ASN D 1 862 ? -10.981 28.115  17.751  1.00 139.98 ? 937  ASN D CA  1 
ATOM   15055 C C   . ASN D 1 862 ? -12.117 28.447  18.711  1.00 147.22 ? 937  ASN D C   1 
ATOM   15056 O O   . ASN D 1 862 ? -12.016 29.418  19.468  1.00 148.75 ? 937  ASN D O   1 
ATOM   15057 C CB  . ASN D 1 862 ? -10.295 29.398  17.284  1.00 146.80 ? 937  ASN D CB  1 
ATOM   15058 C CG  . ASN D 1 862 ? -9.311  29.155  16.160  1.00 158.73 ? 937  ASN D CG  1 
ATOM   15059 O OD1 . ASN D 1 862 ? -8.354  28.395  16.310  1.00 160.18 ? 937  ASN D OD1 1 
ATOM   15060 N ND2 . ASN D 1 862 ? -9.545  29.795  15.021  1.00 150.89 ? 937  ASN D ND2 1 
ATOM   15061 N N   . PHE D 1 863 ? -13.196 27.666  18.685  1.00 156.91 ? 938  PHE D N   1 
ATOM   15062 C CA  . PHE D 1 863 ? -14.327 27.900  19.572  1.00 152.96 ? 938  PHE D CA  1 
ATOM   15063 C C   . PHE D 1 863 ? -13.884 27.868  21.028  1.00 148.28 ? 938  PHE D C   1 
ATOM   15064 O O   . PHE D 1 863 ? -13.025 27.073  21.416  1.00 155.26 ? 938  PHE D O   1 
ATOM   15065 C CB  . PHE D 1 863 ? -15.418 26.852  19.336  1.00 151.20 ? 938  PHE D CB  1 
ATOM   15066 C CG  . PHE D 1 863 ? -15.005 25.446  19.691  1.00 151.83 ? 938  PHE D CG  1 
ATOM   15067 C CD1 . PHE D 1 863 ? -14.206 24.704  18.834  1.00 145.64 ? 938  PHE D CD1 1 
ATOM   15068 C CD2 . PHE D 1 863 ? -15.408 24.871  20.886  1.00 154.72 ? 938  PHE D CD2 1 
ATOM   15069 C CE1 . PHE D 1 863 ? -13.830 23.413  19.154  1.00 153.04 ? 938  PHE D CE1 1 
ATOM   15070 C CE2 . PHE D 1 863 ? -15.033 23.579  21.214  1.00 159.85 ? 938  PHE D CE2 1 
ATOM   15071 C CZ  . PHE D 1 863 ? -14.242 22.850  20.346  1.00 167.35 ? 938  PHE D CZ  1 
ATOM   15072 N N   . ASP D 1 864 ? -14.472 28.745  21.838  1.00 138.25 ? 939  ASP D N   1 
ATOM   15073 C CA  . ASP D 1 864 ? -14.148 28.781  23.256  1.00 146.38 ? 939  ASP D CA  1 
ATOM   15074 C C   . ASP D 1 864 ? -14.935 27.702  23.988  1.00 143.24 ? 939  ASP D C   1 
ATOM   15075 O O   . ASP D 1 864 ? -16.139 27.540  23.766  1.00 143.69 ? 939  ASP D O   1 
ATOM   15076 C CB  . ASP D 1 864 ? -14.445 30.161  23.844  1.00 147.38 ? 939  ASP D CB  1 
ATOM   15077 C CG  . ASP D 1 864 ? -15.911 30.534  23.753  1.00 146.94 ? 939  ASP D CG  1 
ATOM   15078 O OD1 . ASP D 1 864 ? -16.458 30.541  22.630  1.00 150.32 ? 939  ASP D OD1 1 
ATOM   15079 O OD2 . ASP D 1 864 ? -16.515 30.816  24.810  1.00 145.21 ? 939  ASP D OD2 1 
ATOM   15080 N N   . ARG D 1 865 ? -14.249 26.951  24.853  1.00 136.81 ? 940  ARG D N   1 
ATOM   15081 C CA  . ARG D 1 865 ? -14.926 25.893  25.593  1.00 133.66 ? 940  ARG D CA  1 
ATOM   15082 C C   . ARG D 1 865 ? -15.910 26.466  26.604  1.00 136.05 ? 940  ARG D C   1 
ATOM   15083 O O   . ARG D 1 865 ? -16.831 25.760  27.029  1.00 135.32 ? 940  ARG D O   1 
ATOM   15084 C CB  . ARG D 1 865 ? -13.925 24.978  26.317  1.00 132.38 ? 940  ARG D CB  1 
ATOM   15085 C CG  . ARG D 1 865 ? -12.594 24.625  25.616  1.00 135.81 ? 940  ARG D CG  1 
ATOM   15086 C CD  . ARG D 1 865 ? -12.636 24.587  24.091  1.00 135.02 ? 940  ARG D CD  1 
ATOM   15087 N NE  . ARG D 1 865 ? -11.358 25.002  23.523  1.00 138.61 ? 940  ARG D NE  1 
ATOM   15088 C CZ  . ARG D 1 865 ? -11.101 25.088  22.225  1.00 148.25 ? 940  ARG D CZ  1 
ATOM   15089 N NH1 . ARG D 1 865 ? -12.029 24.832  21.319  1.00 155.81 ? 940  ARG D NH1 1 
ATOM   15090 N NH2 . ARG D 1 865 ? -9.887  25.456  21.826  1.00 148.47 ? 940  ARG D NH2 1 
ATOM   15091 N N   . SER D 1 866 ? -15.731 27.730  26.995  1.00 136.09 ? 941  SER D N   1 
ATOM   15092 C CA  . SER D 1 866 ? -16.659 28.381  27.911  1.00 145.81 ? 941  SER D CA  1 
ATOM   15093 C C   . SER D 1 866 ? -17.985 28.724  27.246  1.00 157.10 ? 941  SER D C   1 
ATOM   15094 O O   . SER D 1 866 ? -18.943 29.064  27.949  1.00 152.17 ? 941  SER D O   1 
ATOM   15095 C CB  . SER D 1 866 ? -16.022 29.651  28.475  1.00 141.92 ? 941  SER D CB  1 
ATOM   15096 O OG  . SER D 1 866 ? -15.604 30.512  27.429  1.00 140.61 ? 941  SER D OG  1 
ATOM   15097 N N   . SER D 1 867 ? -18.054 28.651  25.917  1.00 155.46 ? 942  SER D N   1 
ATOM   15098 C CA  . SER D 1 867 ? -19.283 28.979  25.209  1.00 138.65 ? 942  SER D CA  1 
ATOM   15099 C C   . SER D 1 867 ? -20.420 28.079  25.672  1.00 145.22 ? 942  SER D C   1 
ATOM   15100 O O   . SER D 1 867 ? -20.234 26.879  25.892  1.00 148.12 ? 942  SER D O   1 
ATOM   15101 C CB  . SER D 1 867 ? -19.082 28.837  23.698  1.00 138.94 ? 942  SER D CB  1 
ATOM   15102 O OG  . SER D 1 867 ? -18.875 27.483  23.333  1.00 143.61 ? 942  SER D OG  1 
ATOM   15103 N N   . SER D 1 868 ? -21.605 28.676  25.826  1.00 150.92 ? 943  SER D N   1 
ATOM   15104 C CA  . SER D 1 868 ? -22.767 27.920  26.281  1.00 143.75 ? 943  SER D CA  1 
ATOM   15105 C C   . SER D 1 868 ? -23.072 26.748  25.359  1.00 143.61 ? 943  SER D C   1 
ATOM   15106 O O   . SER D 1 868 ? -23.681 25.763  25.789  1.00 144.74 ? 943  SER D O   1 
ATOM   15107 C CB  . SER D 1 868 ? -23.982 28.841  26.385  1.00 131.02 ? 943  SER D CB  1 
ATOM   15108 O OG  . SER D 1 868 ? -24.358 29.322  25.106  1.00 125.02 ? 943  SER D OG  1 
ATOM   15109 N N   . THR D 1 869 ? -22.648 26.826  24.098  1.00 141.90 ? 944  THR D N   1 
ATOM   15110 C CA  . THR D 1 869 ? -22.930 25.750  23.155  1.00 139.24 ? 944  THR D CA  1 
ATOM   15111 C C   . THR D 1 869 ? -22.127 24.497  23.503  1.00 129.90 ? 944  THR D C   1 
ATOM   15112 O O   . THR D 1 869 ? -22.670 23.384  23.547  1.00 128.96 ? 944  THR D O   1 
ATOM   15113 C CB  . THR D 1 869 ? -22.625 26.228  21.734  1.00 130.52 ? 944  THR D CB  1 
ATOM   15114 O OG1 . THR D 1 869 ? -23.045 27.590  21.589  1.00 128.56 ? 944  THR D OG1 1 
ATOM   15115 C CG2 . THR D 1 869 ? -23.378 25.387  20.719  1.00 115.17 ? 944  THR D CG2 1 
ATOM   15116 N N   . PHE D 1 870 ? -20.829 24.665  23.772  1.00 121.82 ? 945  PHE D N   1 
ATOM   15117 C CA  . PHE D 1 870 ? -19.985 23.527  24.130  1.00 121.78 ? 945  PHE D CA  1 
ATOM   15118 C C   . PHE D 1 870 ? -20.378 22.961  25.489  1.00 122.26 ? 945  PHE D C   1 
ATOM   15119 O O   . PHE D 1 870 ? -20.400 21.737  25.681  1.00 127.86 ? 945  PHE D O   1 
ATOM   15120 C CB  . PHE D 1 870 ? -18.517 23.956  24.116  1.00 128.89 ? 945  PHE D CB  1 
ATOM   15121 C CG  . PHE D 1 870 ? -17.543 22.821  24.252  1.00 130.56 ? 945  PHE D CG  1 
ATOM   15122 C CD1 . PHE D 1 870 ? -17.424 21.873  23.252  1.00 120.83 ? 945  PHE D CD1 1 
ATOM   15123 C CD2 . PHE D 1 870 ? -16.732 22.714  25.370  1.00 138.53 ? 945  PHE D CD2 1 
ATOM   15124 C CE1 . PHE D 1 870 ? -16.523 20.831  23.367  1.00 123.37 ? 945  PHE D CE1 1 
ATOM   15125 C CE2 . PHE D 1 870 ? -15.828 21.673  25.491  1.00 131.38 ? 945  PHE D CE2 1 
ATOM   15126 C CZ  . PHE D 1 870 ? -15.725 20.731  24.488  1.00 125.42 ? 945  PHE D CZ  1 
ATOM   15127 N N   . SER D 1 871 ? -20.693 23.842  26.442  1.00 123.26 ? 946  SER D N   1 
ATOM   15128 C CA  . SER D 1 871 ? -21.202 23.391  27.731  1.00 127.67 ? 946  SER D CA  1 
ATOM   15129 C C   . SER D 1 871 ? -22.500 22.616  27.564  1.00 121.52 ? 946  SER D C   1 
ATOM   15130 O O   . SER D 1 871 ? -22.741 21.634  28.274  1.00 114.24 ? 946  SER D O   1 
ATOM   15131 C CB  . SER D 1 871 ? -21.408 24.588  28.660  1.00 127.83 ? 946  SER D CB  1 
ATOM   15132 O OG  . SER D 1 871 ? -20.238 25.382  28.737  1.00 132.42 ? 946  SER D OG  1 
ATOM   15133 N N   . GLY D 1 872 ? -23.341 23.028  26.614  1.00 125.20 ? 947  GLY D N   1 
ATOM   15134 C CA  . GLY D 1 872 ? -24.582 22.310  26.377  1.00 125.88 ? 947  GLY D CA  1 
ATOM   15135 C C   . GLY D 1 872 ? -24.360 20.941  25.766  1.00 122.77 ? 947  GLY D C   1 
ATOM   15136 O O   . GLY D 1 872 ? -25.052 19.978  26.109  1.00 134.87 ? 947  GLY D O   1 
ATOM   15137 N N   . ILE D 1 873 ? -23.399 20.832  24.846  1.00 112.97 ? 948  ILE D N   1 
ATOM   15138 C CA  . ILE D 1 873 ? -23.067 19.515  24.301  1.00 111.85 ? 948  ILE D CA  1 
ATOM   15139 C C   . ILE D 1 873 ? -22.514 18.606  25.395  1.00 110.33 ? 948  ILE D C   1 
ATOM   15140 O O   . ILE D 1 873 ? -22.844 17.415  25.456  1.00 112.70 ? 948  ILE D O   1 
ATOM   15141 C CB  . ILE D 1 873 ? -22.094 19.629  23.112  1.00 107.15 ? 948  ILE D CB  1 
ATOM   15142 C CG1 . ILE D 1 873 ? -22.627 20.608  22.067  1.00 106.48 ? 948  ILE D CG1 1 
ATOM   15143 C CG2 . ILE D 1 873 ? -21.854 18.261  22.486  1.00 90.44  ? 948  ILE D CG2 1 
ATOM   15144 C CD1 . ILE D 1 873 ? -21.697 20.790  20.896  1.00 112.54 ? 948  ILE D CD1 1 
ATOM   15145 N N   . LYS D 1 874 ? -21.675 19.148  26.281  1.00 115.00 ? 949  LYS D N   1 
ATOM   15146 C CA  . LYS D 1 874 ? -21.162 18.330  27.379  1.00 112.75 ? 949  LYS D CA  1 
ATOM   15147 C C   . LYS D 1 874 ? -22.277 17.936  28.345  1.00 120.68 ? 949  LYS D C   1 
ATOM   15148 O O   . LYS D 1 874 ? -22.275 16.824  28.890  1.00 119.46 ? 949  LYS D O   1 
ATOM   15149 C CB  . LYS D 1 874 ? -20.037 19.068  28.106  1.00 102.13 ? 949  LYS D CB  1 
ATOM   15150 C CG  . LYS D 1 874 ? -18.823 19.356  27.232  1.00 111.12 ? 949  LYS D CG  1 
ATOM   15151 C CD  . LYS D 1 874 ? -17.682 19.936  28.048  1.00 119.38 ? 949  LYS D CD  1 
ATOM   15152 C CE  . LYS D 1 874 ? -17.170 18.938  29.072  1.00 119.14 ? 949  LYS D CE  1 
ATOM   15153 N NZ  . LYS D 1 874 ? -15.919 19.420  29.717  1.00 127.27 ? 949  LYS D NZ  1 
ATOM   15154 N N   . GLU D 1 875 ? -23.247 18.829  28.555  1.00 117.98 ? 950  GLU D N   1 
ATOM   15155 C CA  . GLU D 1 875 ? -24.396 18.515  29.399  1.00 109.48 ? 950  GLU D CA  1 
ATOM   15156 C C   . GLU D 1 875 ? -25.241 17.404  28.786  1.00 110.34 ? 950  GLU D C   1 
ATOM   15157 O O   . GLU D 1 875 ? -25.699 16.496  29.492  1.00 115.18 ? 950  GLU D O   1 
ATOM   15158 C CB  . GLU D 1 875 ? -25.227 19.781  29.611  1.00 103.13 ? 950  GLU D CB  1 
ATOM   15159 C CG  . GLU D 1 875 ? -26.563 19.581  30.298  1.00 114.44 ? 950  GLU D CG  1 
ATOM   15160 C CD  . GLU D 1 875 ? -26.425 19.357  31.787  1.00 115.64 ? 950  GLU D CD  1 
ATOM   15161 O OE1 . GLU D 1 875 ? -25.576 20.024  32.413  1.00 121.06 ? 950  GLU D OE1 1 
ATOM   15162 O OE2 . GLU D 1 875 ? -27.181 18.531  32.338  1.00 117.89 ? 950  GLU D OE2 1 
ATOM   15163 N N   . LEU D 1 876 ? -25.449 17.459  27.470  1.00 100.79 ? 951  LEU D N   1 
ATOM   15164 C CA  . LEU D 1 876 ? -26.169 16.391  26.785  1.00 106.02 ? 951  LEU D CA  1 
ATOM   15165 C C   . LEU D 1 876 ? -25.400 15.077  26.859  1.00 102.31 ? 951  LEU D C   1 
ATOM   15166 O O   . LEU D 1 876 ? -25.999 13.999  26.966  1.00 96.85  ? 951  LEU D O   1 
ATOM   15167 C CB  . LEU D 1 876 ? -26.426 16.781  25.328  1.00 101.46 ? 951  LEU D CB  1 
ATOM   15168 C CG  . LEU D 1 876 ? -27.235 15.785  24.496  1.00 101.32 ? 951  LEU D CG  1 
ATOM   15169 C CD1 . LEU D 1 876 ? -28.684 15.732  24.968  1.00 98.40  ? 951  LEU D CD1 1 
ATOM   15170 C CD2 . LEU D 1 876 ? -27.159 16.118  23.015  1.00 87.30  ? 951  LEU D CD2 1 
ATOM   15171 N N   . ALA D 1 877 ? -24.068 15.148  26.798  1.00 98.08  ? 952  ALA D N   1 
ATOM   15172 C CA  . ALA D 1 877 ? -23.258 13.945  26.957  1.00 91.00  ? 952  ALA D CA  1 
ATOM   15173 C C   . ALA D 1 877 ? -23.429 13.348  28.347  1.00 97.00  ? 952  ALA D C   1 
ATOM   15174 O O   . ALA D 1 877 ? -23.536 12.126  28.499  1.00 94.93  ? 952  ALA D O   1 
ATOM   15175 C CB  . ALA D 1 877 ? -21.788 14.261  26.692  1.00 97.76  ? 952  ALA D CB  1 
ATOM   15176 N N   . ARG D 1 878 ? -23.444 14.199  29.375  1.00 99.53  ? 953  ARG D N   1 
ATOM   15177 C CA  . ARG D 1 878 ? -23.693 13.720  30.732  1.00 106.37 ? 953  ARG D CA  1 
ATOM   15178 C C   . ARG D 1 878 ? -25.074 13.089  30.841  1.00 100.75 ? 953  ARG D C   1 
ATOM   15179 O O   . ARG D 1 878 ? -25.257 12.078  31.531  1.00 105.93 ? 953  ARG D O   1 
ATOM   15180 C CB  . ARG D 1 878 ? -23.547 14.870  31.730  1.00 110.96 ? 953  ARG D CB  1 
ATOM   15181 C CG  . ARG D 1 878 ? -23.700 14.458  33.185  1.00 105.78 ? 953  ARG D CG  1 
ATOM   15182 C CD  . ARG D 1 878 ? -24.729 15.318  33.902  1.00 98.56  ? 953  ARG D CD  1 
ATOM   15183 N NE  . ARG D 1 878 ? -26.033 15.265  33.251  1.00 129.52 ? 953  ARG D NE  1 
ATOM   15184 C CZ  . ARG D 1 878 ? -27.112 15.901  33.685  1.00 137.79 ? 953  ARG D CZ  1 
ATOM   15185 N NH1 . ARG D 1 878 ? -27.080 16.655  34.771  1.00 121.60 ? 953  ARG D NH1 1 
ATOM   15186 N NH2 . ARG D 1 878 ? -28.251 15.780  33.009  1.00 171.36 ? 953  ARG D NH2 1 
ATOM   15187 N N   . ARG D 1 879 ? -26.057 13.677  30.159  1.00 95.47  ? 954  ARG D N   1 
ATOM   15188 C CA  . ARG D 1 879 ? -27.415 13.145  30.173  1.00 91.82  ? 954  ARG D CA  1 
ATOM   15189 C C   . ARG D 1 879 ? -27.453 11.749  29.554  1.00 96.60  ? 954  ARG D C   1 
ATOM   15190 O O   . ARG D 1 879 ? -28.040 10.814  30.117  1.00 101.03 ? 954  ARG D O   1 
ATOM   15191 C CB  . ARG D 1 879 ? -28.327 14.117  29.420  1.00 88.39  ? 954  ARG D CB  1 
ATOM   15192 C CG  . ARG D 1 879 ? -29.638 14.478  30.105  1.00 111.22 ? 954  ARG D CG  1 
ATOM   15193 C CD  . ARG D 1 879 ? -30.264 15.681  29.398  1.00 122.10 ? 954  ARG D CD  1 
ATOM   15194 N NE  . ARG D 1 879 ? -31.617 15.987  29.848  1.00 144.13 ? 954  ARG D NE  1 
ATOM   15195 C CZ  . ARG D 1 879 ? -31.995 17.171  30.312  1.00 142.91 ? 954  ARG D CZ  1 
ATOM   15196 N NH1 . ARG D 1 879 ? -31.143 18.180  30.409  1.00 122.09 ? 954  ARG D NH1 1 
ATOM   15197 N NH2 . ARG D 1 879 ? -33.257 17.347  30.694  1.00 147.94 ? 954  ARG D NH2 1 
ATOM   15198 N N   . PHE D 1 880 ? -26.805 11.591  28.396  1.00 86.87  ? 955  PHE D N   1 
ATOM   15199 C CA  . PHE D 1 880 ? -26.681 10.279  27.764  1.00 95.62  ? 955  PHE D CA  1 
ATOM   15200 C C   . PHE D 1 880 ? -25.994 9.285   28.699  1.00 102.62 ? 955  PHE D C   1 
ATOM   15201 O O   . PHE D 1 880 ? -26.440 8.138   28.856  1.00 107.72 ? 955  PHE D O   1 
ATOM   15202 C CB  . PHE D 1 880 ? -25.893 10.409  26.457  1.00 92.72  ? 955  PHE D CB  1 
ATOM   15203 C CG  . PHE D 1 880 ? -26.626 11.140  25.356  1.00 99.83  ? 955  PHE D CG  1 
ATOM   15204 C CD1 . PHE D 1 880 ? -27.955 11.512  25.499  1.00 102.82 ? 955  PHE D CD1 1 
ATOM   15205 C CD2 . PHE D 1 880 ? -25.971 11.467  24.177  1.00 95.65  ? 955  PHE D CD2 1 
ATOM   15206 C CE1 . PHE D 1 880 ? -28.614 12.186  24.481  1.00 94.81  ? 955  PHE D CE1 1 
ATOM   15207 C CE2 . PHE D 1 880 ? -26.624 12.142  23.157  1.00 79.59  ? 955  PHE D CE2 1 
ATOM   15208 C CZ  . PHE D 1 880 ? -27.946 12.500  23.310  1.00 82.96  ? 955  PHE D CZ  1 
ATOM   15209 N N   . ALA D 1 881 ? -24.893 9.714   29.325  1.00 97.33  ? 956  ALA D N   1 
ATOM   15210 C CA  . ALA D 1 881 ? -24.184 8.861   30.272  1.00 96.62  ? 956  ALA D CA  1 
ATOM   15211 C C   . ALA D 1 881 ? -25.106 8.389   31.386  1.00 111.11 ? 956  ALA D C   1 
ATOM   15212 O O   . ALA D 1 881 ? -25.054 7.224   31.795  1.00 115.66 ? 956  ALA D O   1 
ATOM   15213 C CB  . ALA D 1 881 ? -22.982 9.607   30.853  1.00 99.14  ? 956  ALA D CB  1 
ATOM   15214 N N   . LEU D 1 882 ? -25.956 9.285   31.894  1.00 114.03 ? 957  LEU D N   1 
ATOM   15215 C CA  . LEU D 1 882 ? -26.958 8.873   32.871  1.00 99.98  ? 957  LEU D CA  1 
ATOM   15216 C C   . LEU D 1 882 ? -27.900 7.831   32.284  1.00 105.18 ? 957  LEU D C   1 
ATOM   15217 O O   . LEU D 1 882 ? -28.285 6.877   32.971  1.00 108.84 ? 957  LEU D O   1 
ATOM   15218 C CB  . LEU D 1 882 ? -27.745 10.081  33.377  1.00 88.35  ? 957  LEU D CB  1 
ATOM   15219 C CG  . LEU D 1 882 ? -26.936 11.204  34.023  1.00 89.59  ? 957  LEU D CG  1 
ATOM   15220 C CD1 . LEU D 1 882 ? -27.859 12.214  34.682  1.00 92.42  ? 957  LEU D CD1 1 
ATOM   15221 C CD2 . LEU D 1 882 ? -25.942 10.638  35.025  1.00 99.43  ? 957  LEU D CD2 1 
ATOM   15222 N N   . THR D 1 883 ? -28.287 7.997   31.013  1.00 110.40 ? 958  THR D N   1 
ATOM   15223 C CA  . THR D 1 883 ? -29.120 6.977   30.375  1.00 109.53 ? 958  THR D CA  1 
ATOM   15224 C C   . THR D 1 883 ? -28.440 5.614   30.364  1.00 106.44 ? 958  THR D C   1 
ATOM   15225 O O   . THR D 1 883 ? -29.125 4.588   30.445  1.00 108.30 ? 958  THR D O   1 
ATOM   15226 C CB  . THR D 1 883 ? -29.492 7.362   28.941  1.00 105.43 ? 958  THR D CB  1 
ATOM   15227 O OG1 . THR D 1 883 ? -28.379 7.118   28.071  1.00 118.72 ? 958  THR D OG1 1 
ATOM   15228 C CG2 . THR D 1 883 ? -29.928 8.814   28.846  1.00 99.82  ? 958  THR D CG2 1 
ATOM   15229 N N   . PHE D 1 884 ? -27.107 5.577   30.250  1.00 117.18 ? 959  PHE D N   1 
ATOM   15230 C CA  . PHE D 1 884 ? -26.407 4.292   30.312  1.00 122.47 ? 959  PHE D CA  1 
ATOM   15231 C C   . PHE D 1 884 ? -26.752 3.510   31.574  1.00 117.55 ? 959  PHE D C   1 
ATOM   15232 O O   . PHE D 1 884 ? -26.948 2.290   31.520  1.00 120.51 ? 959  PHE D O   1 
ATOM   15233 C CB  . PHE D 1 884 ? -24.894 4.488   30.215  1.00 123.33 ? 959  PHE D CB  1 
ATOM   15234 C CG  . PHE D 1 884 ? -24.393 4.627   28.813  1.00 127.81 ? 959  PHE D CG  1 
ATOM   15235 C CD1 . PHE D 1 884 ? -24.788 5.690   28.023  1.00 126.77 ? 959  PHE D CD1 1 
ATOM   15236 C CD2 . PHE D 1 884 ? -23.527 3.685   28.283  1.00 127.16 ? 959  PHE D CD2 1 
ATOM   15237 C CE1 . PHE D 1 884 ? -24.330 5.812   26.734  1.00 148.98 ? 959  PHE D CE1 1 
ATOM   15238 C CE2 . PHE D 1 884 ? -23.063 3.803   26.992  1.00 140.41 ? 959  PHE D CE2 1 
ATOM   15239 C CZ  . PHE D 1 884 ? -23.468 4.868   26.217  1.00 164.48 ? 959  PHE D CZ  1 
ATOM   15240 N N   . GLY D 1 885 ? -26.818 4.185   32.717  1.00 111.54 ? 960  GLY D N   1 
ATOM   15241 C CA  . GLY D 1 885 ? -27.186 3.531   33.961  1.00 105.26 ? 960  GLY D CA  1 
ATOM   15242 C C   . GLY D 1 885 ? -26.030 2.895   34.708  1.00 104.26 ? 960  GLY D C   1 
ATOM   15243 O O   . GLY D 1 885 ? -25.164 2.252   34.112  1.00 110.17 ? 960  GLY D O   1 
ATOM   15244 N N   . LEU D 1 889 ? -26.050 -3.959  35.221  1.00 129.44 ? 964  LEU D N   1 
ATOM   15245 C CA  . LEU D 1 889 ? -26.106 -2.926  34.192  1.00 146.63 ? 964  LEU D CA  1 
ATOM   15246 C C   . LEU D 1 889 ? -25.808 -3.514  32.816  1.00 164.81 ? 964  LEU D C   1 
ATOM   15247 O O   . LEU D 1 889 ? -26.533 -3.256  31.855  1.00 212.40 ? 964  LEU D O   1 
ATOM   15248 C CB  . LEU D 1 889 ? -25.125 -1.794  34.505  1.00 133.66 ? 964  LEU D CB  1 
ATOM   15249 C CG  . LEU D 1 889 ? -25.412 -0.918  35.727  1.00 111.49 ? 964  LEU D CG  1 
ATOM   15250 C CD1 . LEU D 1 889 ? -26.904 -0.656  35.862  1.00 117.07 ? 964  LEU D CD1 1 
ATOM   15251 C CD2 . LEU D 1 889 ? -24.847 -1.536  36.999  1.00 97.36  ? 964  LEU D CD2 1 
ATOM   15252 N N   . LYS D 1 890 ? -24.731 -4.299  32.737  1.00 163.14 ? 965  LYS D N   1 
ATOM   15253 C CA  . LYS D 1 890 ? -24.340 -5.000  31.512  1.00 152.47 ? 965  LYS D CA  1 
ATOM   15254 C C   . LYS D 1 890 ? -24.085 -4.036  30.356  1.00 148.43 ? 965  LYS D C   1 
ATOM   15255 O O   . LYS D 1 890 ? -24.323 -4.368  29.191  1.00 139.80 ? 965  LYS D O   1 
ATOM   15256 C CB  . LYS D 1 890 ? -25.388 -6.048  31.121  1.00 138.13 ? 965  LYS D CB  1 
ATOM   15257 C CG  . LYS D 1 890 ? -25.683 -7.054  32.223  1.00 141.88 ? 965  LYS D CG  1 
ATOM   15258 C CD  . LYS D 1 890 ? -27.014 -7.755  32.007  1.00 144.31 ? 965  LYS D CD  1 
ATOM   15259 C CE  . LYS D 1 890 ? -28.168 -6.766  32.062  1.00 146.97 ? 965  LYS D CE  1 
ATOM   15260 N NZ  . LYS D 1 890 ? -29.494 -7.443  32.074  1.00 134.87 ? 965  LYS D NZ  1 
ATOM   15261 N N   . THR D 1 891 ? -23.593 -2.838  30.668  1.00 148.27 ? 966  THR D N   1 
ATOM   15262 C CA  . THR D 1 891 ? -23.258 -1.833  29.669  1.00 139.25 ? 966  THR D CA  1 
ATOM   15263 C C   . THR D 1 891 ? -21.759 -1.737  29.422  1.00 131.58 ? 966  THR D C   1 
ATOM   15264 O O   . THR D 1 891 ? -21.314 -0.811  28.735  1.00 130.12 ? 966  THR D O   1 
ATOM   15265 C CB  . THR D 1 891 ? -23.787 -0.462  30.095  1.00 151.45 ? 966  THR D CB  1 
ATOM   15266 O OG1 . THR D 1 891 ? -22.949 0.070   31.128  1.00 208.09 ? 966  THR D OG1 1 
ATOM   15267 C CG2 . THR D 1 891 ? -25.201 -0.575  30.627  1.00 146.92 ? 966  THR D CG2 1 
ATOM   15268 N N   . ARG D 1 892 ? -20.975 -2.668  29.973  1.00 129.52 ? 967  ARG D N   1 
ATOM   15269 C CA  . ARG D 1 892 ? -19.518 -2.576  29.930  1.00 119.98 ? 967  ARG D CA  1 
ATOM   15270 C C   . ARG D 1 892 ? -19.021 -2.428  28.493  1.00 117.29 ? 967  ARG D C   1 
ATOM   15271 O O   . ARG D 1 892 ? -18.325 -1.462  28.146  1.00 114.15 ? 967  ARG D O   1 
ATOM   15272 C CB  . ARG D 1 892 ? -18.898 -3.820  30.581  1.00 130.17 ? 967  ARG D CB  1 
ATOM   15273 C CG  . ARG D 1 892 ? -19.262 -4.084  32.053  1.00 140.27 ? 967  ARG D CG  1 
ATOM   15274 C CD  . ARG D 1 892 ? -20.619 -4.782  32.188  1.00 150.00 ? 967  ARG D CD  1 
ATOM   15275 N NE  . ARG D 1 892 ? -20.998 -5.041  33.573  1.00 150.59 ? 967  ARG D NE  1 
ATOM   15276 C CZ  . ARG D 1 892 ? -21.761 -4.247  34.312  1.00 141.38 ? 967  ARG D CZ  1 
ATOM   15277 N NH1 . ARG D 1 892 ? -22.224 -3.100  33.843  1.00 144.05 ? 967  ARG D NH1 1 
ATOM   15278 N NH2 . ARG D 1 892 ? -22.059 -4.609  35.557  1.00 134.29 ? 967  ARG D NH2 1 
ATOM   15279 N N   . GLU D 1 893 ? -19.387 -3.392  27.643  1.00 117.35 ? 968  GLU D N   1 
ATOM   15280 C CA  . GLU D 1 893 ? -18.993 -3.357  26.238  1.00 106.46 ? 968  GLU D CA  1 
ATOM   15281 C C   . GLU D 1 893 ? -19.476 -2.084  25.559  1.00 109.59 ? 968  GLU D C   1 
ATOM   15282 O O   . GLU D 1 893 ? -18.754 -1.491  24.749  1.00 104.96 ? 968  GLU D O   1 
ATOM   15283 C CB  . GLU D 1 893 ? -19.547 -4.586  25.517  1.00 86.59  ? 968  GLU D CB  1 
ATOM   15284 C CG  . GLU D 1 893 ? -18.990 -4.821  24.121  1.00 108.03 ? 968  GLU D CG  1 
ATOM   15285 C CD  . GLU D 1 893 ? -19.249 -6.235  23.635  1.00 120.68 ? 968  GLU D CD  1 
ATOM   15286 O OE1 . GLU D 1 893 ? -19.359 -7.142  24.488  1.00 102.63 ? 968  GLU D OE1 1 
ATOM   15287 O OE2 . GLU D 1 893 ? -19.346 -6.444  22.407  1.00 132.89 ? 968  GLU D OE2 1 
ATOM   15288 N N   . ALA D 1 894 ? -20.694 -1.643  25.884  1.00 101.34 ? 969  ALA D N   1 
ATOM   15289 C CA  . ALA D 1 894 ? -21.272 -0.485  25.211  1.00 90.37  ? 969  ALA D CA  1 
ATOM   15290 C C   . ALA D 1 894 ? -20.508 0.791   25.546  1.00 100.34 ? 969  ALA D C   1 
ATOM   15291 O O   . ALA D 1 894 ? -20.175 1.581   24.653  1.00 104.89 ? 969  ALA D O   1 
ATOM   15292 C CB  . ALA D 1 894 ? -22.747 -0.346  25.585  1.00 101.53 ? 969  ALA D CB  1 
ATOM   15293 N N   . ILE D 1 895 ? -20.225 1.013   26.831  1.00 106.61 ? 970  ILE D N   1 
ATOM   15294 C CA  . ILE D 1 895 ? -19.511 2.223   27.225  1.00 106.40 ? 970  ILE D CA  1 
ATOM   15295 C C   . ILE D 1 895 ? -18.080 2.198   26.692  1.00 107.46 ? 970  ILE D C   1 
ATOM   15296 O O   . ILE D 1 895 ? -17.548 3.228   26.248  1.00 99.32  ? 970  ILE D O   1 
ATOM   15297 C CB  . ILE D 1 895 ? -19.574 2.403   28.758  1.00 102.85 ? 970  ILE D CB  1 
ATOM   15298 C CG1 . ILE D 1 895 ? -19.028 3.771   29.173  1.00 107.89 ? 970  ILE D CG1 1 
ATOM   15299 C CG2 . ILE D 1 895 ? -18.869 1.271   29.495  1.00 108.14 ? 970  ILE D CG2 1 
ATOM   15300 C CD1 . ILE D 1 895 ? -19.844 4.934   28.652  1.00 96.12  ? 970  ILE D CD1 1 
ATOM   15301 N N   . ALA D 1 896 ? -17.448 1.016   26.677  1.00 108.09 ? 971  ALA D N   1 
ATOM   15302 C CA  . ALA D 1 896 ? -16.107 0.920   26.104  1.00 100.17 ? 971  ALA D CA  1 
ATOM   15303 C C   . ALA D 1 896 ? -16.115 1.252   24.614  1.00 99.45  ? 971  ALA D C   1 
ATOM   15304 O O   . ALA D 1 896 ? -15.236 1.974   24.121  1.00 91.73  ? 971  ALA D O   1 
ATOM   15305 C CB  . ALA D 1 896 ? -15.533 -0.476  26.343  1.00 95.49  ? 971  ALA D CB  1 
ATOM   15306 N N   . MET D 1 897 ? -17.107 0.739   23.880  1.00 99.56  ? 972  MET D N   1 
ATOM   15307 C CA  . MET D 1 897 ? -17.195 1.009   22.449  1.00 93.10  ? 972  MET D CA  1 
ATOM   15308 C C   . MET D 1 897 ? -17.458 2.486   22.179  1.00 93.36  ? 972  MET D C   1 
ATOM   15309 O O   . MET D 1 897 ? -16.909 3.060   21.228  1.00 104.64 ? 972  MET D O   1 
ATOM   15310 C CB  . MET D 1 897 ? -18.290 0.138   21.830  1.00 89.00  ? 972  MET D CB  1 
ATOM   15311 C CG  . MET D 1 897 ? -18.633 0.458   20.384  1.00 96.77  ? 972  MET D CG  1 
ATOM   15312 S SD  . MET D 1 897 ? -17.368 -0.052  19.205  1.00 120.69 ? 972  MET D SD  1 
ATOM   15313 C CE  . MET D 1 897 ? -16.983 1.511   18.418  1.00 107.75 ? 972  MET D CE  1 
ATOM   15314 N N   . LEU D 1 898 ? -18.307 3.116   22.997  1.00 83.99  ? 973  LEU D N   1 
ATOM   15315 C CA  . LEU D 1 898 ? -18.525 4.553   22.861  1.00 88.88  ? 973  LEU D CA  1 
ATOM   15316 C C   . LEU D 1 898 ? -17.221 5.319   23.041  1.00 104.41 ? 973  LEU D C   1 
ATOM   15317 O O   . LEU D 1 898 ? -16.904 6.218   22.252  1.00 103.81 ? 973  LEU D O   1 
ATOM   15318 C CB  . LEU D 1 898 ? -19.594 5.024   23.854  1.00 82.80  ? 973  LEU D CB  1 
ATOM   15319 C CG  . LEU D 1 898 ? -19.849 6.524   24.046  1.00 86.20  ? 973  LEU D CG  1 
ATOM   15320 C CD1 . LEU D 1 898 ? -21.274 6.770   24.473  1.00 93.07  ? 973  LEU D CD1 1 
ATOM   15321 C CD2 . LEU D 1 898 ? -18.933 7.084   25.113  1.00 99.61  ? 973  LEU D CD2 1 
ATOM   15322 N N   . HIS D 1 899 ? -16.448 4.973   24.077  1.00 109.68 ? 974  HIS D N   1 
ATOM   15323 C CA  . HIS D 1 899 ? -15.157 5.633   24.274  1.00 101.50 ? 974  HIS D CA  1 
ATOM   15324 C C   . HIS D 1 899 ? -14.237 5.432   23.076  1.00 98.25  ? 974  HIS D C   1 
ATOM   15325 O O   . HIS D 1 899 ? -13.543 6.365   22.653  1.00 95.78  ? 974  HIS D O   1 
ATOM   15326 C CB  . HIS D 1 899 ? -14.486 5.122   25.547  1.00 101.09 ? 974  HIS D CB  1 
ATOM   15327 C CG  . HIS D 1 899 ? -15.054 5.703   26.803  1.00 105.56 ? 974  HIS D CG  1 
ATOM   15328 N ND1 . HIS D 1 899 ? -16.323 5.411   27.253  1.00 109.33 ? 974  HIS D ND1 1 
ATOM   15329 C CD2 . HIS D 1 899 ? -14.526 6.570   27.700  1.00 106.57 ? 974  HIS D CD2 1 
ATOM   15330 C CE1 . HIS D 1 899 ? -16.550 6.068   28.376  1.00 102.96 ? 974  HIS D CE1 1 
ATOM   15331 N NE2 . HIS D 1 899 ? -15.476 6.779   28.668  1.00 105.56 ? 974  HIS D NE2 1 
ATOM   15332 N N   . LYS D 1 900 ? -14.208 4.216   22.527  1.00 96.67  ? 975  LYS D N   1 
ATOM   15333 C CA  . LYS D 1 900 ? -13.335 3.931   21.390  1.00 92.80  ? 975  LYS D CA  1 
ATOM   15334 C C   . LYS D 1 900 ? -13.706 4.792   20.189  1.00 95.81  ? 975  LYS D C   1 
ATOM   15335 O O   . LYS D 1 900 ? -12.840 5.418   19.562  1.00 99.90  ? 975  LYS D O   1 
ATOM   15336 C CB  . LYS D 1 900 ? -13.417 2.447   21.033  1.00 88.18  ? 975  LYS D CB  1 
ATOM   15337 C CG  . LYS D 1 900 ? -12.442 1.997   19.959  1.00 115.62 ? 975  LYS D CG  1 
ATOM   15338 C CD  . LYS D 1 900 ? -11.019 2.416   20.287  1.00 132.71 ? 975  LYS D CD  1 
ATOM   15339 C CE  . LYS D 1 900 ? -10.050 1.969   19.207  1.00 116.98 ? 975  LYS D CE  1 
ATOM   15340 N NZ  . LYS D 1 900 ? -8.642  2.272   19.576  1.00 94.82  ? 975  LYS D NZ  1 
ATOM   15341 N N   . ASP D 1 901 ? -14.996 4.822   19.846  1.00 99.34  ? 976  ASP D N   1 
ATOM   15342 C CA  . ASP D 1 901 ? -15.439 5.643   18.725  1.00 98.89  ? 976  ASP D CA  1 
ATOM   15343 C C   . ASP D 1 901 ? -15.126 7.113   18.970  1.00 95.68  ? 976  ASP D C   1 
ATOM   15344 O O   . ASP D 1 901 ? -14.696 7.828   18.054  1.00 105.18 ? 976  ASP D O   1 
ATOM   15345 C CB  . ASP D 1 901 ? -16.936 5.440   18.486  1.00 110.61 ? 976  ASP D CB  1 
ATOM   15346 C CG  . ASP D 1 901 ? -17.310 5.523   17.019  1.00 133.70 ? 976  ASP D CG  1 
ATOM   15347 O OD1 . ASP D 1 901 ? -16.787 4.712   16.226  1.00 140.09 ? 976  ASP D OD1 1 
ATOM   15348 O OD2 . ASP D 1 901 ? -18.125 6.398   16.659  1.00 139.51 ? 976  ASP D OD2 1 
ATOM   15349 N N   . GLY D 1 902 ? -15.310 7.576   20.208  1.00 92.71  ? 977  GLY D N   1 
ATOM   15350 C CA  . GLY D 1 902 ? -15.039 8.971   20.511  1.00 102.12 ? 977  GLY D CA  1 
ATOM   15351 C C   . GLY D 1 902 ? -13.578 9.333   20.335  1.00 113.07 ? 977  GLY D C   1 
ATOM   15352 O O   . GLY D 1 902 ? -13.247 10.367  19.747  1.00 110.27 ? 977  GLY D O   1 
ATOM   15353 N N   . ILE D 1 903 ? -12.678 8.487   20.843  1.00 115.78 ? 978  ILE D N   1 
ATOM   15354 C CA  . ILE D 1 903 ? -11.257 8.799   20.721  1.00 111.67 ? 978  ILE D CA  1 
ATOM   15355 C C   . ILE D 1 903 ? -10.813 8.705   19.267  1.00 111.73 ? 978  ILE D C   1 
ATOM   15356 O O   . ILE D 1 903 ? -9.951  9.472   18.821  1.00 115.84 ? 978  ILE D O   1 
ATOM   15357 C CB  . ILE D 1 903 ? -10.401 7.901   21.636  1.00 103.20 ? 978  ILE D CB  1 
ATOM   15358 C CG1 . ILE D 1 903 ? -10.413 6.449   21.156  1.00 103.37 ? 978  ILE D CG1 1 
ATOM   15359 C CG2 . ILE D 1 903 ? -10.861 8.017   23.082  1.00 95.63  ? 978  ILE D CG2 1 
ATOM   15360 C CD1 . ILE D 1 903 ? -9.688  5.496   22.072  1.00 97.61  ? 978  ILE D CD1 1 
ATOM   15361 N N   . GLU D 1 904 ? -11.395 7.780   18.496  1.00 111.71 ? 979  GLU D N   1 
ATOM   15362 C CA  . GLU D 1 904 ? -11.048 7.712   17.081  1.00 100.99 ? 979  GLU D CA  1 
ATOM   15363 C C   . GLU D 1 904 ? -11.501 8.967   16.348  1.00 102.80 ? 979  GLU D C   1 
ATOM   15364 O O   . GLU D 1 904 ? -10.800 9.462   15.458  1.00 99.91  ? 979  GLU D O   1 
ATOM   15365 C CB  . GLU D 1 904 ? -11.652 6.463   16.443  1.00 97.02  ? 979  GLU D CB  1 
ATOM   15366 C CG  . GLU D 1 904 ? -11.027 5.169   16.924  1.00 98.31  ? 979  GLU D CG  1 
ATOM   15367 C CD  . GLU D 1 904 ? -11.858 3.962   16.555  1.00 110.86 ? 979  GLU D CD  1 
ATOM   15368 O OE1 . GLU D 1 904 ? -13.077 3.981   16.820  1.00 117.30 ? 979  GLU D OE1 1 
ATOM   15369 O OE2 . GLU D 1 904 ? -11.293 2.999   15.996  1.00 122.97 ? 979  GLU D OE2 1 
ATOM   15370 N N   . PHE D 1 905 ? -12.666 9.503   16.720  1.00 111.13 ? 980  PHE D N   1 
ATOM   15371 C CA  . PHE D 1 905 ? -13.113 10.767  16.140  1.00 120.97 ? 980  PHE D CA  1 
ATOM   15372 C C   . PHE D 1 905 ? -12.203 11.919  16.549  1.00 123.01 ? 980  PHE D C   1 
ATOM   15373 O O   . PHE D 1 905 ? -11.945 12.827  15.750  1.00 122.52 ? 980  PHE D O   1 
ATOM   15374 C CB  . PHE D 1 905 ? -14.556 11.049  16.557  1.00 112.12 ? 980  PHE D CB  1 
ATOM   15375 C CG  . PHE D 1 905 ? -15.046 12.419  16.178  1.00 117.14 ? 980  PHE D CG  1 
ATOM   15376 C CD1 . PHE D 1 905 ? -15.166 12.786  14.849  1.00 123.39 ? 980  PHE D CD1 1 
ATOM   15377 C CD2 . PHE D 1 905 ? -15.397 13.335  17.155  1.00 113.89 ? 980  PHE D CD2 1 
ATOM   15378 C CE1 . PHE D 1 905 ? -15.622 14.045  14.502  1.00 130.49 ? 980  PHE D CE1 1 
ATOM   15379 C CE2 . PHE D 1 905 ? -15.854 14.594  16.815  1.00 104.62 ? 980  PHE D CE2 1 
ATOM   15380 C CZ  . PHE D 1 905 ? -15.967 14.950  15.488  1.00 116.92 ? 980  PHE D CZ  1 
ATOM   15381 N N   . ALA D 1 906 ? -11.710 11.900  17.791  1.00 118.15 ? 981  ALA D N   1 
ATOM   15382 C CA  . ALA D 1 906 ? -10.872 12.995  18.272  1.00 119.93 ? 981  ALA D CA  1 
ATOM   15383 C C   . ALA D 1 906 ? -9.545  13.054  17.525  1.00 120.80 ? 981  ALA D C   1 
ATOM   15384 O O   . ALA D 1 906 ? -9.049  14.143  17.212  1.00 119.49 ? 981  ALA D O   1 
ATOM   15385 C CB  . ALA D 1 906 ? -10.635 12.852  19.775  1.00 113.70 ? 981  ALA D CB  1 
ATOM   15386 N N   . PHE D 1 907 ? -8.955  11.897  17.237  1.00 119.66 ? 982  PHE D N   1 
ATOM   15387 C CA  . PHE D 1 907 ? -7.701  11.816  16.503  1.00 123.12 ? 982  PHE D CA  1 
ATOM   15388 C C   . PHE D 1 907 ? -7.912  11.622  15.008  1.00 129.09 ? 982  PHE D C   1 
ATOM   15389 O O   . PHE D 1 907 ? -6.952  11.322  14.290  1.00 126.59 ? 982  PHE D O   1 
ATOM   15390 C CB  . PHE D 1 907 ? -6.841  10.681  17.062  1.00 115.75 ? 982  PHE D CB  1 
ATOM   15391 C CG  . PHE D 1 907 ? -6.408  10.897  18.483  1.00 121.41 ? 982  PHE D CG  1 
ATOM   15392 C CD1 . PHE D 1 907 ? -5.628  11.988  18.824  1.00 127.13 ? 982  PHE D CD1 1 
ATOM   15393 C CD2 . PHE D 1 907 ? -6.792  10.017  19.479  1.00 124.48 ? 982  PHE D CD2 1 
ATOM   15394 C CE1 . PHE D 1 907 ? -5.231  12.194  20.132  1.00 123.75 ? 982  PHE D CE1 1 
ATOM   15395 C CE2 . PHE D 1 907 ? -6.397  10.216  20.788  1.00 128.26 ? 982  PHE D CE2 1 
ATOM   15396 C CZ  . PHE D 1 907 ? -5.617  11.306  21.115  1.00 119.85 ? 982  PHE D CZ  1 
ATOM   15397 N N   . LYS D 1 908 ? -9.146  11.785  14.527  1.00 133.26 ? 983  LYS D N   1 
ATOM   15398 C CA  . LYS D 1 908 ? -9.427  11.595  13.108  1.00 133.77 ? 983  LYS D CA  1 
ATOM   15399 C C   . LYS D 1 908 ? -8.706  12.634  12.258  1.00 134.99 ? 983  LYS D C   1 
ATOM   15400 O O   . LYS D 1 908 ? -8.058  12.296  11.261  1.00 133.38 ? 983  LYS D O   1 
ATOM   15401 C CB  . LYS D 1 908 ? -10.937 11.650  12.869  1.00 126.71 ? 983  LYS D CB  1 
ATOM   15402 C CG  . LYS D 1 908 ? -11.347 11.614  11.408  1.00 129.45 ? 983  LYS D CG  1 
ATOM   15403 C CD  . LYS D 1 908 ? -12.859 11.682  11.272  1.00 135.07 ? 983  LYS D CD  1 
ATOM   15404 C CE  . LYS D 1 908 ? -13.289 11.719  9.816   1.00 152.51 ? 983  LYS D CE  1 
ATOM   15405 N NZ  . LYS D 1 908 ? -12.749 12.913  9.112   1.00 162.52 ? 983  LYS D NZ  1 
ATOM   15406 N N   . GLU D 1 909 ? -8.804  13.904  12.639  1.00 131.42 ? 984  GLU D N   1 
ATOM   15407 C CA  . GLU D 1 909 ? -8.242  14.986  11.839  1.00 142.36 ? 984  GLU D CA  1 
ATOM   15408 C C   . GLU D 1 909 ? -7.009  15.557  12.521  1.00 145.49 ? 984  GLU D C   1 
ATOM   15409 O O   . GLU D 1 909 ? -7.130  16.157  13.602  1.00 138.46 ? 984  GLU D O   1 
ATOM   15410 C CB  . GLU D 1 909 ? -9.284  16.084  11.619  1.00 146.75 ? 984  GLU D CB  1 
ATOM   15411 C CG  . GLU D 1 909 ? -10.483 15.649  10.794  1.00 151.85 ? 984  GLU D CG  1 
ATOM   15412 C CD  . GLU D 1 909 ? -10.095 15.160  9.412   1.00 151.54 ? 984  GLU D CD  1 
ATOM   15413 O OE1 . GLU D 1 909 ? -9.595  15.976  8.609   1.00 155.44 ? 984  GLU D OE1 1 
ATOM   15414 O OE2 . GLU D 1 909 ? -10.297 13.961  9.124   1.00 148.99 ? 984  GLU D OE2 1 
ATOM   15415 N N   . PRO D 1 910 ? -5.819  15.402  11.948  1.00 146.54 ? 985  PRO D N   1 
ATOM   15416 C CA  . PRO D 1 910 ? -4.626  15.996  12.550  1.00 138.56 ? 985  PRO D CA  1 
ATOM   15417 C C   . PRO D 1 910 ? -4.432  17.432  12.087  1.00 133.75 ? 985  PRO D C   1 
ATOM   15418 O O   . PRO D 1 910 ? -4.991  17.875  11.083  1.00 122.19 ? 985  PRO D O   1 
ATOM   15419 C CB  . PRO D 1 910 ? -3.501  15.093  12.040  1.00 119.97 ? 985  PRO D CB  1 
ATOM   15420 C CG  . PRO D 1 910 ? -3.972  14.707  10.676  1.00 108.37 ? 985  PRO D CG  1 
ATOM   15421 C CD  . PRO D 1 910 ? -5.484  14.582  10.770  1.00 126.05 ? 985  PRO D CD  1 
ATOM   15422 N N   . ASN D 1 911 ? -3.633  18.163  12.853  1.00 141.49 ? 986  ASN D N   1 
ATOM   15423 C CA  . ASN D 1 911 ? -3.340  19.547  12.498  1.00 149.97 ? 986  ASN D CA  1 
ATOM   15424 C C   . ASN D 1 911 ? -2.308  19.584  11.378  1.00 166.07 ? 986  ASN D C   1 
ATOM   15425 O O   . ASN D 1 911 ? -1.252  18.955  11.497  1.00 163.28 ? 986  ASN D O   1 
ATOM   15426 C CB  . ASN D 1 911 ? -2.819  20.322  13.702  1.00 146.12 ? 986  ASN D CB  1 
ATOM   15427 C CG  . ASN D 1 911 ? -2.800  21.821  13.468  1.00 150.07 ? 986  ASN D CG  1 
ATOM   15428 O OD1 . ASN D 1 911 ? -2.110  22.315  12.578  1.00 161.29 ? 986  ASN D OD1 1 
ATOM   15429 N ND2 . ASN D 1 911 ? -3.557  22.554  14.276  1.00 134.24 ? 986  ASN D ND2 1 
ATOM   15430 N N   . PRO D 1 912 ? -2.574  20.301  10.285  1.00 176.58 ? 987  PRO D N   1 
ATOM   15431 C CA  . PRO D 1 912 ? -1.560  20.385  9.222   1.00 175.05 ? 987  PRO D CA  1 
ATOM   15432 C C   . PRO D 1 912 ? -0.364  21.226  9.619   1.00 172.07 ? 987  PRO D C   1 
ATOM   15433 O O   . PRO D 1 912 ? 0.779   20.861  9.310   1.00 173.65 ? 987  PRO D O   1 
ATOM   15434 C CB  . PRO D 1 912 ? -2.333  21.005  8.049   1.00 176.53 ? 987  PRO D CB  1 
ATOM   15435 C CG  . PRO D 1 912 ? -3.471  21.740  8.682   1.00 171.12 ? 987  PRO D CG  1 
ATOM   15436 C CD  . PRO D 1 912 ? -3.820  21.007  9.942   1.00 163.71 ? 987  PRO D CD  1 
ATOM   15437 N N   . GLN D 1 913 ? -0.600  22.347  10.304  1.00 166.35 ? 988  GLN D N   1 
ATOM   15438 C CA  . GLN D 1 913 ? 0.484   23.253  10.673  1.00 160.27 ? 988  GLN D CA  1 
ATOM   15439 C C   . GLN D 1 913 ? 1.481   22.573  11.604  1.00 157.53 ? 988  GLN D C   1 
ATOM   15440 O O   . GLN D 1 913 ? 2.697   22.650  11.385  1.00 163.65 ? 988  GLN D O   1 
ATOM   15441 C CB  . GLN D 1 913 ? -0.100  24.506  11.325  1.00 148.80 ? 988  GLN D CB  1 
ATOM   15442 C CG  . GLN D 1 913 ? 0.917   25.417  11.979  1.00 144.44 ? 988  GLN D CG  1 
ATOM   15443 C CD  . GLN D 1 913 ? 0.307   26.242  13.092  1.00 150.54 ? 988  GLN D CD  1 
ATOM   15444 O OE1 . GLN D 1 913 ? -0.676  26.954  12.881  1.00 160.66 ? 988  GLN D OE1 1 
ATOM   15445 N NE2 . GLN D 1 913 ? 0.881   26.149  14.285  1.00 147.45 ? 988  GLN D NE2 1 
ATOM   15446 N N   . GLY D 1 914 ? 0.994   21.905  12.636  1.00 153.33 ? 989  GLY D N   1 
ATOM   15447 C CA  . GLY D 1 914 ? 1.852   21.211  13.568  1.00 158.65 ? 989  GLY D CA  1 
ATOM   15448 C C   . GLY D 1 914 ? 1.826   19.714  13.344  1.00 164.53 ? 989  GLY D C   1 
ATOM   15449 O O   . GLY D 1 914 ? 0.786   19.071  13.500  1.00 197.89 ? 989  GLY D O   1 
ATOM   15450 N N   . GLU D 1 915 ? 2.983   19.161  12.974  1.00 167.60 ? 990  GLU D N   1 
ATOM   15451 C CA  . GLU D 1 915 ? 3.071   17.730  12.704  1.00 171.75 ? 990  GLU D CA  1 
ATOM   15452 C C   . GLU D 1 915 ? 2.655   16.919  13.926  1.00 161.09 ? 990  GLU D C   1 
ATOM   15453 O O   . GLU D 1 915 ? 1.911   15.937  13.814  1.00 153.52 ? 990  GLU D O   1 
ATOM   15454 C CB  . GLU D 1 915 ? 4.492   17.372  12.263  1.00 182.42 ? 990  GLU D CB  1 
ATOM   15455 C CG  . GLU D 1 915 ? 5.041   18.272  11.159  1.00 183.13 ? 990  GLU D CG  1 
ATOM   15456 C CD  . GLU D 1 915 ? 4.073   18.440  10.001  1.00 187.29 ? 990  GLU D CD  1 
ATOM   15457 O OE1 . GLU D 1 915 ? 3.780   17.438  9.315   1.00 185.26 ? 990  GLU D OE1 1 
ATOM   15458 O OE2 . GLU D 1 915 ? 3.604   19.577  9.777   1.00 184.85 ? 990  GLU D OE2 1 
ATOM   15459 N N   . SER D 1 916 ? 3.119   17.323  15.106  1.00 156.47 ? 991  SER D N   1 
ATOM   15460 C CA  . SER D 1 916 ? 2.698   16.724  16.362  1.00 155.87 ? 991  SER D CA  1 
ATOM   15461 C C   . SER D 1 916 ? 1.781   17.637  17.162  1.00 166.12 ? 991  SER D C   1 
ATOM   15462 O O   . SER D 1 916 ? 1.293   17.232  18.222  1.00 179.39 ? 991  SER D O   1 
ATOM   15463 C CB  . SER D 1 916 ? 3.917   16.349  17.206  1.00 152.35 ? 991  SER D CB  1 
ATOM   15464 O OG  . SER D 1 916 ? 3.557   15.476  18.261  1.00 160.36 ? 991  SER D OG  1 
ATOM   15465 N N   . HIS D 1 917 ? 1.548   18.856  16.686  1.00 155.98 ? 992  HIS D N   1 
ATOM   15466 C CA  . HIS D 1 917 ? 0.669   19.805  17.350  1.00 154.45 ? 992  HIS D CA  1 
ATOM   15467 C C   . HIS D 1 917 ? -0.786  19.367  17.160  1.00 159.45 ? 992  HIS D C   1 
ATOM   15468 O O   . HIS D 1 917 ? -1.072  18.448  16.386  1.00 182.45 ? 992  HIS D O   1 
ATOM   15469 C CB  . HIS D 1 917 ? 0.976   21.207  16.828  1.00 139.72 ? 992  HIS D CB  1 
ATOM   15470 N N   . PRO D 1 918 ? -1.743  20.031  17.825  1.00 157.98 ? 993  PRO D N   1 
ATOM   15471 C CA  . PRO D 1 918 ? -2.866  19.295  18.401  1.00 148.03 ? 993  PRO D CA  1 
ATOM   15472 C C   . PRO D 1 918 ? -3.802  18.737  17.341  1.00 145.49 ? 993  PRO D C   1 
ATOM   15473 O O   . PRO D 1 918 ? -4.007  19.353  16.284  1.00 153.50 ? 993  PRO D O   1 
ATOM   15474 C CB  . PRO D 1 918 ? -3.569  20.358  19.261  1.00 136.23 ? 993  PRO D CB  1 
ATOM   15475 C CG  . PRO D 1 918 ? -3.428  21.581  18.432  1.00 132.21 ? 993  PRO D CG  1 
ATOM   15476 C CD  . PRO D 1 918 ? -2.089  21.465  17.709  1.00 147.33 ? 993  PRO D CD  1 
ATOM   15477 N N   . PRO D 1 919 ? -4.393  17.569  17.590  1.00 135.14 ? 994  PRO D N   1 
ATOM   15478 C CA  . PRO D 1 919 ? -5.466  17.081  16.716  1.00 130.84 ? 994  PRO D CA  1 
ATOM   15479 C C   . PRO D 1 919 ? -6.640  18.050  16.706  1.00 134.20 ? 994  PRO D C   1 
ATOM   15480 O O   . PRO D 1 919 ? -6.934  18.718  17.701  1.00 144.44 ? 994  PRO D O   1 
ATOM   15481 C CB  . PRO D 1 919 ? -5.853  15.738  17.344  1.00 123.95 ? 994  PRO D CB  1 
ATOM   15482 C CG  . PRO D 1 919 ? -4.665  15.332  18.149  1.00 117.68 ? 994  PRO D CG  1 
ATOM   15483 C CD  . PRO D 1 919 ? -4.035  16.598  18.635  1.00 127.67 ? 994  PRO D CD  1 
ATOM   15484 N N   . LEU D 1 920 ? -7.315  18.117  15.560  1.00 132.32 ? 995  LEU D N   1 
ATOM   15485 C CA  . LEU D 1 920 ? -8.371  19.107  15.382  1.00 134.97 ? 995  LEU D CA  1 
ATOM   15486 C C   . LEU D 1 920 ? -9.588  18.793  16.247  1.00 136.56 ? 995  LEU D C   1 
ATOM   15487 O O   . LEU D 1 920 ? -10.193 19.701  16.830  1.00 126.13 ? 995  LEU D O   1 
ATOM   15488 C CB  . LEU D 1 920 ? -8.759  19.187  13.906  1.00 136.54 ? 995  LEU D CB  1 
ATOM   15489 C CG  . LEU D 1 920 ? -7.625  19.545  12.943  1.00 130.36 ? 995  LEU D CG  1 
ATOM   15490 C CD1 . LEU D 1 920 ? -8.163  19.732  11.537  1.00 126.98 ? 995  LEU D CD1 1 
ATOM   15491 C CD2 . LEU D 1 920 ? -6.890  20.795  13.408  1.00 141.17 ? 995  LEU D CD2 1 
ATOM   15492 N N   . ASN D 1 921 ? -9.957  17.518  16.354  1.00 142.25 ? 996  ASN D N   1 
ATOM   15493 C CA  . ASN D 1 921 ? -11.128 17.105  17.116  1.00 134.05 ? 996  ASN D CA  1 
ATOM   15494 C C   . ASN D 1 921 ? -10.777 16.658  18.531  1.00 124.30 ? 996  ASN D C   1 
ATOM   15495 O O   . ASN D 1 921 ? -11.591 15.997  19.184  1.00 127.58 ? 996  ASN D O   1 
ATOM   15496 C CB  . ASN D 1 921 ? -11.867 15.990  16.376  1.00 133.38 ? 996  ASN D CB  1 
ATOM   15497 C CG  . ASN D 1 921 ? -12.044 16.291  14.903  1.00 146.68 ? 996  ASN D CG  1 
ATOM   15498 O OD1 . ASN D 1 921 ? -11.069 16.491  14.182  1.00 176.90 ? 996  ASN D OD1 1 
ATOM   15499 N ND2 . ASN D 1 921 ? -13.291 16.323  14.447  1.00 133.81 ? 996  ASN D ND2 1 
ATOM   15500 N N   . LEU D 1 922 ? -9.584  17.010  19.017  1.00 122.76 ? 997  LEU D N   1 
ATOM   15501 C CA  . LEU D 1 922 ? -9.163  16.578  20.346  1.00 125.85 ? 997  LEU D CA  1 
ATOM   15502 C C   . LEU D 1 922 ? -10.109 17.083  21.430  1.00 123.05 ? 997  LEU D C   1 
ATOM   15503 O O   . LEU D 1 922 ? -10.326 16.395  22.436  1.00 108.66 ? 997  LEU D O   1 
ATOM   15504 C CB  . LEU D 1 922 ? -7.734  17.052  20.617  1.00 113.01 ? 997  LEU D CB  1 
ATOM   15505 C CG  . LEU D 1 922 ? -7.105  16.658  21.954  1.00 116.11 ? 997  LEU D CG  1 
ATOM   15506 C CD1 . LEU D 1 922 ? -6.684  15.194  21.949  1.00 111.38 ? 997  LEU D CD1 1 
ATOM   15507 C CD2 . LEU D 1 922 ? -5.926  17.561  22.279  1.00 118.61 ? 997  LEU D CD2 1 
ATOM   15508 N N   . ALA D 1 923 ? -10.698 18.267  21.232  1.00 112.80 ? 998  ALA D N   1 
ATOM   15509 C CA  . ALA D 1 923 ? -11.591 18.838  22.237  1.00 109.77 ? 998  ALA D CA  1 
ATOM   15510 C C   . ALA D 1 923 ? -12.786 17.937  22.515  1.00 116.32 ? 998  ALA D C   1 
ATOM   15511 O O   . ALA D 1 923 ? -13.364 17.998  23.608  1.00 108.84 ? 998  ALA D O   1 
ATOM   15512 C CB  . ALA D 1 923 ? -12.066 20.221  21.794  1.00 109.58 ? 998  ALA D CB  1 
ATOM   15513 N N   . PHE D 1 924 ? -13.168 17.096  21.548  1.00 119.79 ? 999  PHE D N   1 
ATOM   15514 C CA  . PHE D 1 924 ? -14.268 16.162  21.762  1.00 112.55 ? 999  PHE D CA  1 
ATOM   15515 C C   . PHE D 1 924 ? -14.014 15.253  22.955  1.00 112.93 ? 999  PHE D C   1 
ATOM   15516 O O   . PHE D 1 924 ? -14.966 14.817  23.613  1.00 119.51 ? 999  PHE D O   1 
ATOM   15517 C CB  . PHE D 1 924 ? -14.500 15.322  20.507  1.00 117.35 ? 999  PHE D CB  1 
ATOM   15518 C CG  . PHE D 1 924 ? -15.788 14.554  20.523  1.00 112.54 ? 999  PHE D CG  1 
ATOM   15519 C CD1 . PHE D 1 924 ? -17.004 15.213  20.447  1.00 102.43 ? 999  PHE D CD1 1 
ATOM   15520 C CD2 . PHE D 1 924 ? -15.785 13.172  20.623  1.00 102.60 ? 999  PHE D CD2 1 
ATOM   15521 C CE1 . PHE D 1 924 ? -18.191 14.509  20.465  1.00 101.24 ? 999  PHE D CE1 1 
ATOM   15522 C CE2 . PHE D 1 924 ? -16.968 12.462  20.642  1.00 94.14  ? 999  PHE D CE2 1 
ATOM   15523 C CZ  . PHE D 1 924 ? -18.173 13.132  20.562  1.00 95.16  ? 999  PHE D CZ  1 
ATOM   15524 N N   . LEU D 1 925 ? -12.743 14.958  23.247  1.00 111.37 ? 1000 LEU D N   1 
ATOM   15525 C CA  . LEU D 1 925 ? -12.417 14.165  24.427  1.00 110.27 ? 1000 LEU D CA  1 
ATOM   15526 C C   . LEU D 1 925 ? -13.030 14.773  25.681  1.00 106.79 ? 1000 LEU D C   1 
ATOM   15527 O O   . LEU D 1 925 ? -13.544 14.049  26.543  1.00 110.90 ? 1000 LEU D O   1 
ATOM   15528 C CB  . LEU D 1 925 ? -10.900 14.040  24.573  1.00 107.04 ? 1000 LEU D CB  1 
ATOM   15529 C CG  . LEU D 1 925 ? -10.219 13.102  23.575  1.00 98.71  ? 1000 LEU D CG  1 
ATOM   15530 C CD1 . LEU D 1 925 ? -8.790  12.806  23.999  1.00 122.07 ? 1000 LEU D CD1 1 
ATOM   15531 C CD2 . LEU D 1 925 ? -11.015 11.814  23.418  1.00 106.24 ? 1000 LEU D CD2 1 
ATOM   15532 N N   . ASP D 1 926 ? -12.992 16.105  25.789  1.00 97.67  ? 1001 ASP D N   1 
ATOM   15533 C CA  . ASP D 1 926 ? -13.687 16.804  26.865  1.00 106.87 ? 1001 ASP D CA  1 
ATOM   15534 C C   . ASP D 1 926 ? -15.108 16.277  27.013  1.00 111.67 ? 1001 ASP D C   1 
ATOM   15535 O O   . ASP D 1 926 ? -15.495 15.769  28.072  1.00 104.75 ? 1001 ASP D O   1 
ATOM   15536 C CB  . ASP D 1 926 ? -13.693 18.310  26.580  1.00 106.56 ? 1001 ASP D CB  1 
ATOM   15537 C CG  . ASP D 1 926 ? -13.277 19.138  27.780  1.00 120.73 ? 1001 ASP D CG  1 
ATOM   15538 O OD1 . ASP D 1 926 ? -13.141 18.568  28.884  1.00 133.57 ? 1001 ASP D OD1 1 
ATOM   15539 O OD2 . ASP D 1 926 ? -13.083 20.360  27.615  1.00 112.07 ? 1001 ASP D OD2 1 
ATOM   15540 N N   . ILE D 1 927 ? -15.885 16.353  25.929  1.00 113.62 ? 1002 ILE D N   1 
ATOM   15541 C CA  . ILE D 1 927 ? -17.238 15.804  25.928  1.00 100.63 ? 1002 ILE D CA  1 
ATOM   15542 C C   . ILE D 1 927 ? -17.215 14.336  26.334  1.00 100.22 ? 1002 ILE D C   1 
ATOM   15543 O O   . ILE D 1 927 ? -17.973 13.904  27.211  1.00 104.14 ? 1002 ILE D O   1 
ATOM   15544 C CB  . ILE D 1 927 ? -17.885 16.003  24.547  1.00 87.72  ? 1002 ILE D CB  1 
ATOM   15545 C CG1 . ILE D 1 927 ? -17.616 17.421  24.047  1.00 100.46 ? 1002 ILE D CG1 1 
ATOM   15546 C CG2 . ILE D 1 927 ? -19.377 15.746  24.607  1.00 97.60  ? 1002 ILE D CG2 1 
ATOM   15547 C CD1 . ILE D 1 927 ? -18.233 17.717  22.714  1.00 110.74 ? 1002 ILE D CD1 1 
ATOM   15548 N N   . LEU D 1 928 ? -16.315 13.556  25.726  1.00 95.09  ? 1003 LEU D N   1 
ATOM   15549 C CA  . LEU D 1 928 ? -16.233 12.130  26.024  1.00 89.78  ? 1003 LEU D CA  1 
ATOM   15550 C C   . LEU D 1 928 ? -15.931 11.870  27.494  1.00 97.62  ? 1003 LEU D C   1 
ATOM   15551 O O   . LEU D 1 928 ? -16.291 10.806  28.013  1.00 89.30  ? 1003 LEU D O   1 
ATOM   15552 C CB  . LEU D 1 928 ? -15.168 11.483  25.137  1.00 90.12  ? 1003 LEU D CB  1 
ATOM   15553 C CG  . LEU D 1 928 ? -15.153 9.958   25.074  1.00 91.06  ? 1003 LEU D CG  1 
ATOM   15554 C CD1 . LEU D 1 928 ? -16.431 9.470   24.429  1.00 98.94  ? 1003 LEU D CD1 1 
ATOM   15555 C CD2 . LEU D 1 928 ? -13.946 9.458   24.306  1.00 88.04  ? 1003 LEU D CD2 1 
ATOM   15556 N N   . SER D 1 929 ? -15.309 12.834  28.178  1.00 111.58 ? 1004 SER D N   1 
ATOM   15557 C CA  . SER D 1 929 ? -15.022 12.676  29.599  1.00 105.41 ? 1004 SER D CA  1 
ATOM   15558 C C   . SER D 1 929 ? -16.291 12.480  30.417  1.00 104.39 ? 1004 SER D C   1 
ATOM   15559 O O   . SER D 1 929 ? -16.243 11.875  31.494  1.00 98.91  ? 1004 SER D O   1 
ATOM   15560 C CB  . SER D 1 929 ? -14.242 13.889  30.113  1.00 102.70 ? 1004 SER D CB  1 
ATOM   15561 O OG  . SER D 1 929 ? -13.083 14.114  29.327  1.00 110.83 ? 1004 SER D OG  1 
ATOM   15562 N N   . GLU D 1 930 ? -17.434 12.966  29.924  1.00 108.46 ? 1005 GLU D N   1 
ATOM   15563 C CA  . GLU D 1 930 ? -18.685 12.768  30.645  1.00 99.37  ? 1005 GLU D CA  1 
ATOM   15564 C C   . GLU D 1 930 ? -19.056 11.295  30.757  1.00 99.32  ? 1005 GLU D C   1 
ATOM   15565 O O   . GLU D 1 930 ? -19.818 10.924  31.657  1.00 90.79  ? 1005 GLU D O   1 
ATOM   15566 C CB  . GLU D 1 930 ? -19.818 13.540  29.966  1.00 82.05  ? 1005 GLU D CB  1 
ATOM   15567 C CG  . GLU D 1 930 ? -19.569 15.036  29.831  1.00 92.03  ? 1005 GLU D CG  1 
ATOM   15568 C CD  . GLU D 1 930 ? -19.162 15.686  31.139  1.00 109.46 ? 1005 GLU D CD  1 
ATOM   15569 O OE1 . GLU D 1 930 ? -19.962 15.657  32.100  1.00 93.31  ? 1005 GLU D OE1 1 
ATOM   15570 O OE2 . GLU D 1 930 ? -18.043 16.238  31.200  1.00 123.27 ? 1005 GLU D OE2 1 
ATOM   15571 N N   . PHE D 1 931 ? -18.531 10.447  29.872  1.00 101.44 ? 1006 PHE D N   1 
ATOM   15572 C CA  . PHE D 1 931 ? -18.859 9.027   29.879  1.00 94.28  ? 1006 PHE D CA  1 
ATOM   15573 C C   . PHE D 1 931 ? -17.847 8.179   30.636  1.00 105.05 ? 1006 PHE D C   1 
ATOM   15574 O O   . PHE D 1 931 ? -18.085 6.979   30.816  1.00 109.07 ? 1006 PHE D O   1 
ATOM   15575 C CB  . PHE D 1 931 ? -18.977 8.509   28.443  1.00 92.17  ? 1006 PHE D CB  1 
ATOM   15576 C CG  . PHE D 1 931 ? -20.068 9.164   27.650  1.00 94.48  ? 1006 PHE D CG  1 
ATOM   15577 C CD1 . PHE D 1 931 ? -21.393 8.830   27.864  1.00 96.93  ? 1006 PHE D CD1 1 
ATOM   15578 C CD2 . PHE D 1 931 ? -19.770 10.123  26.699  1.00 102.72 ? 1006 PHE D CD2 1 
ATOM   15579 C CE1 . PHE D 1 931 ? -22.399 9.434   27.138  1.00 95.36  ? 1006 PHE D CE1 1 
ATOM   15580 C CE2 . PHE D 1 931 ? -20.772 10.729  25.971  1.00 93.57  ? 1006 PHE D CE2 1 
ATOM   15581 C CZ  . PHE D 1 931 ? -22.088 10.385  26.191  1.00 88.40  ? 1006 PHE D CZ  1 
ATOM   15582 N N   . SER D 1 932 ? -16.733 8.765   31.082  1.00 99.29  ? 1007 SER D N   1 
ATOM   15583 C CA  . SER D 1 932 ? -15.729 7.991   31.805  1.00 101.06 ? 1007 SER D CA  1 
ATOM   15584 C C   . SER D 1 932 ? -16.263 7.477   33.135  1.00 102.79 ? 1007 SER D C   1 
ATOM   15585 O O   . SER D 1 932 ? -15.754 6.481   33.662  1.00 99.26  ? 1007 SER D O   1 
ATOM   15586 C CB  . SER D 1 932 ? -14.479 8.841   32.032  1.00 112.99 ? 1007 SER D CB  1 
ATOM   15587 O OG  . SER D 1 932 ? -13.978 9.351   30.810  1.00 99.73  ? 1007 SER D OG  1 
ATOM   15588 N N   . SER D 1 933 ? -17.277 8.141   33.693  1.00 108.32 ? 1008 SER D N   1 
ATOM   15589 C CA  . SER D 1 933 ? -17.820 7.726   34.983  1.00 104.09 ? 1008 SER D CA  1 
ATOM   15590 C C   . SER D 1 933 ? -18.409 6.323   34.904  1.00 104.54 ? 1008 SER D C   1 
ATOM   15591 O O   . SER D 1 933 ? -18.090 5.455   35.725  1.00 103.92 ? 1008 SER D O   1 
ATOM   15592 C CB  . SER D 1 933 ? -18.876 8.727   35.452  1.00 97.38  ? 1008 SER D CB  1 
ATOM   15593 O OG  . SER D 1 933 ? -18.363 10.047  35.456  1.00 117.18 ? 1008 SER D OG  1 
ATOM   15594 N N   . LYS D 1 934 ? -19.267 6.081   33.910  1.00 103.16 ? 1009 LYS D N   1 
ATOM   15595 C CA  . LYS D 1 934 ? -19.902 4.778   33.762  1.00 93.87  ? 1009 LYS D CA  1 
ATOM   15596 C C   . LYS D 1 934 ? -18.892 3.686   33.439  1.00 96.94  ? 1009 LYS D C   1 
ATOM   15597 O O   . LYS D 1 934 ? -19.170 2.506   33.677  1.00 91.00  ? 1009 LYS D O   1 
ATOM   15598 C CB  . LYS D 1 934 ? -20.965 4.837   32.666  1.00 102.36 ? 1009 LYS D CB  1 
ATOM   15599 C CG  . LYS D 1 934 ? -22.138 5.743   32.997  1.00 104.14 ? 1009 LYS D CG  1 
ATOM   15600 C CD  . LYS D 1 934 ? -22.990 5.190   34.124  1.00 89.44  ? 1009 LYS D CD  1 
ATOM   15601 C CE  . LYS D 1 934 ? -23.996 6.227   34.593  1.00 89.60  ? 1009 LYS D CE  1 
ATOM   15602 N NZ  . LYS D 1 934 ? -24.720 5.789   35.814  1.00 105.53 ? 1009 LYS D NZ  1 
ATOM   15603 N N   . LEU D 1 935 ? -17.734 4.059   32.906  1.00 109.41 ? 1010 LEU D N   1 
ATOM   15604 C CA  . LEU D 1 935 ? -16.703 3.096   32.557  1.00 112.55 ? 1010 LEU D CA  1 
ATOM   15605 C C   . LEU D 1 935 ? -16.152 2.420   33.806  1.00 110.99 ? 1010 LEU D C   1 
ATOM   15606 O O   . LEU D 1 935 ? -15.934 3.063   34.836  1.00 110.20 ? 1010 LEU D O   1 
ATOM   15607 C CB  . LEU D 1 935 ? -15.582 3.799   31.799  1.00 105.12 ? 1010 LEU D CB  1 
ATOM   15608 C CG  . LEU D 1 935 ? -14.703 3.016   30.833  1.00 105.28 ? 1010 LEU D CG  1 
ATOM   15609 C CD1 . LEU D 1 935 ? -15.503 2.488   29.659  1.00 96.49  ? 1010 LEU D CD1 1 
ATOM   15610 C CD2 . LEU D 1 935 ? -13.624 3.946   30.356  1.00 114.17 ? 1010 LEU D CD2 1 
ATOM   15611 N N   . LEU D 1 936 ? -15.927 1.113   33.709  1.00 105.80 ? 1011 LEU D N   1 
ATOM   15612 C CA  . LEU D 1 936 ? -15.407 0.352   34.831  1.00 115.32 ? 1011 LEU D CA  1 
ATOM   15613 C C   . LEU D 1 936 ? -13.878 0.451   34.860  1.00 129.64 ? 1011 LEU D C   1 
ATOM   15614 O O   . LEU D 1 936 ? -13.241 0.891   33.900  1.00 129.51 ? 1011 LEU D O   1 
ATOM   15615 C CB  . LEU D 1 936 ? -15.877 -1.100  34.742  1.00 112.09 ? 1011 LEU D CB  1 
ATOM   15616 C CG  . LEU D 1 936 ? -15.921 -1.956  36.011  1.00 125.41 ? 1011 LEU D CG  1 
ATOM   15617 C CD1 . LEU D 1 936 ? -16.893 -1.370  37.014  1.00 120.23 ? 1011 LEU D CD1 1 
ATOM   15618 C CD2 . LEU D 1 936 ? -16.329 -3.377  35.669  1.00 120.68 ? 1011 LEU D CD2 1 
ATOM   15619 N N   . ARG D 1 937 ? -13.290 0.041   35.989  1.00 124.50 ? 1012 ARG D N   1 
ATOM   15620 C CA  . ARG D 1 937 ? -11.847 0.182   36.182  1.00 117.86 ? 1012 ARG D CA  1 
ATOM   15621 C C   . ARG D 1 937 ? -11.080 -0.571  35.100  1.00 114.73 ? 1012 ARG D C   1 
ATOM   15622 O O   . ARG D 1 937 ? -10.205 -0.009  34.424  1.00 114.08 ? 1012 ARG D O   1 
ATOM   15623 C CB  . ARG D 1 937 ? -11.443 -0.333  37.569  1.00 119.28 ? 1012 ARG D CB  1 
ATOM   15624 C CG  . ARG D 1 937 ? -12.130 0.344   38.761  1.00 143.95 ? 1012 ARG D CG  1 
ATOM   15625 C CD  . ARG D 1 937 ? -13.466 -0.340  39.040  1.00 145.58 ? 1012 ARG D CD  1 
ATOM   15626 N NE  . ARG D 1 937 ? -14.407 0.471   39.805  1.00 144.69 ? 1012 ARG D NE  1 
ATOM   15627 C CZ  . ARG D 1 937 ? -15.393 1.177   39.267  1.00 152.37 ? 1012 ARG D CZ  1 
ATOM   15628 N NH1 . ARG D 1 937 ? -15.508 1.319   37.958  1.00 156.71 ? 1012 ARG D NH1 1 
ATOM   15629 N NH2 . ARG D 1 937 ? -16.278 1.769   40.063  1.00 155.02 ? 1012 ARG D NH2 1 
ATOM   15630 N N   . GLN D 1 938 ? -11.395 -1.858  34.932  1.00 106.68 ? 1013 GLN D N   1 
ATOM   15631 C CA  . GLN D 1 938 ? -10.810 -2.644  33.851  1.00 105.48 ? 1013 GLN D CA  1 
ATOM   15632 C C   . GLN D 1 938 ? -11.095 -2.007  32.498  1.00 113.18 ? 1013 GLN D C   1 
ATOM   15633 O O   . GLN D 1 938 ? -10.207 -1.923  31.637  1.00 118.09 ? 1013 GLN D O   1 
ATOM   15634 C CB  . GLN D 1 938 ? -11.362 -4.067  33.894  1.00 108.50 ? 1013 GLN D CB  1 
ATOM   15635 C CG  . GLN D 1 938 ? -11.692 -4.557  35.292  1.00 103.17 ? 1013 GLN D CG  1 
ATOM   15636 C CD  . GLN D 1 938 ? -12.772 -5.621  35.293  1.00 124.30 ? 1013 GLN D CD  1 
ATOM   15637 O OE1 . GLN D 1 938 ? -13.885 -5.386  35.758  1.00 141.21 ? 1013 GLN D OE1 1 
ATOM   15638 N NE2 . GLN D 1 938 ? -12.449 -6.797  34.767  1.00 135.33 ? 1013 GLN D NE2 1 
ATOM   15639 N N   . ASP D 1 939 ? -12.335 -1.558  32.291  1.00 122.18 ? 1014 ASP D N   1 
ATOM   15640 C CA  . ASP D 1 939 ? -12.678 -0.867  31.055  1.00 112.52 ? 1014 ASP D CA  1 
ATOM   15641 C C   . ASP D 1 939 ? -11.885 0.423   30.905  1.00 111.04 ? 1014 ASP D C   1 
ATOM   15642 O O   . ASP D 1 939 ? -11.548 0.819   29.784  1.00 113.33 ? 1014 ASP D O   1 
ATOM   15643 C CB  . ASP D 1 939 ? -14.179 -0.578  31.020  1.00 116.93 ? 1014 ASP D CB  1 
ATOM   15644 C CG  . ASP D 1 939 ? -15.014 -1.802  31.324  1.00 125.44 ? 1014 ASP D CG  1 
ATOM   15645 O OD1 . ASP D 1 939 ? -14.427 -2.888  31.513  1.00 115.87 ? 1014 ASP D OD1 1 
ATOM   15646 O OD2 . ASP D 1 939 ? -16.256 -1.678  31.383  1.00 127.64 ? 1014 ASP D OD2 1 
ATOM   15647 N N   . LYS D 1 940 ? -11.572 1.087   32.020  1.00 111.13 ? 1015 LYS D N   1 
ATOM   15648 C CA  . LYS D 1 940 ? -10.748 2.288   31.953  1.00 115.16 ? 1015 LYS D CA  1 
ATOM   15649 C C   . LYS D 1 940 ? -9.343  1.954   31.468  1.00 117.36 ? 1015 LYS D C   1 
ATOM   15650 O O   . LYS D 1 940 ? -8.781  2.664   30.626  1.00 120.45 ? 1015 LYS D O   1 
ATOM   15651 C CB  . LYS D 1 940 ? -10.702 2.969   33.320  1.00 110.34 ? 1015 LYS D CB  1 
ATOM   15652 C CG  . LYS D 1 940 ? -11.946 3.780   33.656  1.00 107.59 ? 1015 LYS D CG  1 
ATOM   15653 C CD  . LYS D 1 940 ? -11.827 4.419   35.029  1.00 119.16 ? 1015 LYS D CD  1 
ATOM   15654 C CE  . LYS D 1 940 ? -12.895 5.478   35.263  1.00 111.83 ? 1015 LYS D CE  1 
ATOM   15655 N NZ  . LYS D 1 940 ? -14.271 4.913   35.205  1.00 111.40 ? 1015 LYS D NZ  1 
ATOM   15656 N N   . ARG D 1 941 ? -8.766  0.864   31.978  1.00 113.01 ? 1016 ARG D N   1 
ATOM   15657 C CA  . ARG D 1 941 ? -7.453  0.428   31.505  1.00 117.52 ? 1016 ARG D CA  1 
ATOM   15658 C C   . ARG D 1 941 ? -7.493  0.071   30.020  1.00 119.87 ? 1016 ARG D C   1 
ATOM   15659 O O   . ARG D 1 941 ? -6.566  0.393   29.260  1.00 128.13 ? 1016 ARG D O   1 
ATOM   15660 C CB  . ARG D 1 941 ? -6.982  -0.761  32.346  1.00 115.06 ? 1016 ARG D CB  1 
ATOM   15661 C CG  . ARG D 1 941 ? -5.602  -1.316  32.029  1.00 137.78 ? 1016 ARG D CG  1 
ATOM   15662 C CD  . ARG D 1 941 ? -4.505  -0.269  32.154  1.00 155.78 ? 1016 ARG D CD  1 
ATOM   15663 N NE  . ARG D 1 941 ? -4.169  0.332   30.869  1.00 173.56 ? 1016 ARG D NE  1 
ATOM   15664 C CZ  . ARG D 1 941 ? -3.258  1.280   30.702  1.00 168.74 ? 1016 ARG D CZ  1 
ATOM   15665 N NH1 . ARG D 1 941 ? -2.609  1.805   31.728  1.00 145.59 ? 1016 ARG D NH1 1 
ATOM   15666 N NH2 . ARG D 1 941 ? -2.984  1.706   29.473  1.00 195.38 ? 1016 ARG D NH2 1 
ATOM   15667 N N   . THR D 1 942 ? -8.574  -0.582  29.585  1.00 112.16 ? 1017 THR D N   1 
ATOM   15668 C CA  . THR D 1 942 ? -8.690  -0.970  28.181  1.00 100.82 ? 1017 THR D CA  1 
ATOM   15669 C C   . THR D 1 942 ? -8.806  0.251   27.270  1.00 110.99 ? 1017 THR D C   1 
ATOM   15670 O O   . THR D 1 942 ? -8.142  0.326   26.227  1.00 121.54 ? 1017 THR D O   1 
ATOM   15671 C CB  . THR D 1 942 ? -9.889  -1.898  27.995  1.00 96.83  ? 1017 THR D CB  1 
ATOM   15672 O OG1 . THR D 1 942 ? -9.850  -2.936  28.983  1.00 109.81 ? 1017 THR D OG1 1 
ATOM   15673 C CG2 . THR D 1 942 ? -9.866  -2.523  26.611  1.00 117.50 ? 1017 THR D CG2 1 
ATOM   15674 N N   . VAL D 1 943 ? -9.643  1.223   27.639  1.00 106.33 ? 1018 VAL D N   1 
ATOM   15675 C CA  . VAL D 1 943 ? -9.725  2.423   26.819  1.00 112.48 ? 1018 VAL D CA  1 
ATOM   15676 C C   . VAL D 1 943 ? -8.438  3.227   26.905  1.00 121.12 ? 1018 VAL D C   1 
ATOM   15677 O O   . VAL D 1 943 ? -8.127  3.983   25.981  1.00 130.30 ? 1018 VAL D O   1 
ATOM   15678 C CB  . VAL D 1 943 ? -10.926 3.307   27.201  1.00 109.12 ? 1018 VAL D CB  1 
ATOM   15679 C CG1 . VAL D 1 943 ? -12.223 2.508   27.143  1.00 106.15 ? 1018 VAL D CG1 1 
ATOM   15680 C CG2 . VAL D 1 943 ? -10.707 3.942   28.556  1.00 120.18 ? 1018 VAL D CG2 1 
ATOM   15681 N N   . TYR D 1 944 ? -7.656  3.075   27.977  1.00 116.56 ? 1019 TYR D N   1 
ATOM   15682 C CA  . TYR D 1 944 ? -6.369  3.755   27.992  1.00 114.51 ? 1019 TYR D CA  1 
ATOM   15683 C C   . TYR D 1 944 ? -5.384  3.105   27.035  1.00 118.38 ? 1019 TYR D C   1 
ATOM   15684 O O   . TYR D 1 944 ? -4.575  3.807   26.427  1.00 120.28 ? 1019 TYR D O   1 
ATOM   15685 C CB  . TYR D 1 944 ? -5.772  3.803   29.398  1.00 116.19 ? 1019 TYR D CB  1 
ATOM   15686 C CG  . TYR D 1 944 ? -4.807  4.959   29.557  1.00 123.47 ? 1019 TYR D CG  1 
ATOM   15687 C CD1 . TYR D 1 944 ? -5.248  6.274   29.465  1.00 119.71 ? 1019 TYR D CD1 1 
ATOM   15688 C CD2 . TYR D 1 944 ? -3.449  4.738   29.745  1.00 121.72 ? 1019 TYR D CD2 1 
ATOM   15689 C CE1 . TYR D 1 944 ? -4.366  7.334   29.590  1.00 115.73 ? 1019 TYR D CE1 1 
ATOM   15690 C CE2 . TYR D 1 944 ? -2.562  5.788   29.865  1.00 118.59 ? 1019 TYR D CE2 1 
ATOM   15691 C CZ  . TYR D 1 944 ? -3.025  7.084   29.789  1.00 118.57 ? 1019 TYR D CZ  1 
ATOM   15692 O OH  . TYR D 1 944 ? -2.139  8.128   29.913  1.00 111.49 ? 1019 TYR D OH  1 
ATOM   15693 N N   . VAL D 1 945 ? -5.429  1.779   26.875  1.00 120.88 ? 1020 VAL D N   1 
ATOM   15694 C CA  . VAL D 1 945 ? -4.545  1.199   25.862  1.00 120.94 ? 1020 VAL D CA  1 
ATOM   15695 C C   . VAL D 1 945 ? -5.032  1.586   24.467  1.00 120.18 ? 1020 VAL D C   1 
ATOM   15696 O O   . VAL D 1 945 ? -4.221  1.827   23.557  1.00 130.45 ? 1020 VAL D O   1 
ATOM   15697 C CB  . VAL D 1 945 ? -4.393  -0.333  26.012  1.00 109.31 ? 1020 VAL D CB  1 
ATOM   15698 C CG1 . VAL D 1 945 ? -3.937  -0.703  27.421  1.00 119.84 ? 1020 VAL D CG1 1 
ATOM   15699 C CG2 . VAL D 1 945 ? -5.652  -1.089  25.614  1.00 104.59 ? 1020 VAL D CG2 1 
ATOM   15700 N N   . TYR D 1 946 ? -6.352  1.687   24.279  1.00 117.33 ? 1021 TYR D N   1 
ATOM   15701 C CA  . TYR D 1 946 ? -6.874  2.179   23.004  1.00 123.63 ? 1021 TYR D CA  1 
ATOM   15702 C C   . TYR D 1 946 ? -6.400  3.601   22.722  1.00 120.11 ? 1021 TYR D C   1 
ATOM   15703 O O   . TYR D 1 946 ? -6.045  3.932   21.584  1.00 130.02 ? 1021 TYR D O   1 
ATOM   15704 C CB  . TYR D 1 946 ? -8.401  2.115   22.987  1.00 125.50 ? 1021 TYR D CB  1 
ATOM   15705 C CG  . TYR D 1 946 ? -8.979  0.717   23.027  1.00 149.37 ? 1021 TYR D CG  1 
ATOM   15706 C CD1 . TYR D 1 946 ? -8.161  -0.402  22.909  1.00 148.69 ? 1021 TYR D CD1 1 
ATOM   15707 C CD2 . TYR D 1 946 ? -10.343 0.517   23.180  1.00 169.63 ? 1021 TYR D CD2 1 
ATOM   15708 C CE1 . TYR D 1 946 ? -8.690  -1.676  22.944  1.00 149.37 ? 1021 TYR D CE1 1 
ATOM   15709 C CE2 . TYR D 1 946 ? -10.881 -0.754  23.216  1.00 163.93 ? 1021 TYR D CE2 1 
ATOM   15710 C CZ  . TYR D 1 946 ? -10.051 -1.847  23.099  1.00 161.36 ? 1021 TYR D CZ  1 
ATOM   15711 O OH  . TYR D 1 946 ? -10.587 -3.113  23.136  1.00 151.91 ? 1021 TYR D OH  1 
ATOM   15712 N N   . LEU D 1 947 ? -6.398  4.458   23.746  1.00 110.40 ? 1022 LEU D N   1 
ATOM   15713 C CA  . LEU D 1 947 ? -5.878  5.814   23.593  1.00 102.05 ? 1022 LEU D CA  1 
ATOM   15714 C C   . LEU D 1 947 ? -4.384  5.795   23.292  1.00 119.88 ? 1022 LEU D C   1 
ATOM   15715 O O   . LEU D 1 947 ? -3.908  6.533   22.421  1.00 126.26 ? 1022 LEU D O   1 
ATOM   15716 C CB  . LEU D 1 947 ? -6.166  6.620   24.861  1.00 97.41  ? 1022 LEU D CB  1 
ATOM   15717 C CG  . LEU D 1 947 ? -5.984  8.140   24.839  1.00 97.64  ? 1022 LEU D CG  1 
ATOM   15718 C CD1 . LEU D 1 947 ? -7.008  8.798   23.933  1.00 106.02 ? 1022 LEU D CD1 1 
ATOM   15719 C CD2 . LEU D 1 947 ? -6.076  8.704   26.250  1.00 95.93  ? 1022 LEU D CD2 1 
ATOM   15720 N N   . GLU D 1 948 ? -3.635  4.953   24.010  1.00 125.00 ? 1023 GLU D N   1 
ATOM   15721 C CA  . GLU D 1 948 ? -2.210  4.767   23.758  1.00 115.70 ? 1023 GLU D CA  1 
ATOM   15722 C C   . GLU D 1 948 ? -1.941  4.462   22.295  1.00 115.49 ? 1023 GLU D C   1 
ATOM   15723 O O   . GLU D 1 948 ? -0.936  4.913   21.732  1.00 124.04 ? 1023 GLU D O   1 
ATOM   15724 C CB  . GLU D 1 948 ? -1.679  3.632   24.630  1.00 106.81 ? 1023 GLU D CB  1 
ATOM   15725 C CG  . GLU D 1 948 ? -1.186  4.046   25.996  1.00 103.82 ? 1023 GLU D CG  1 
ATOM   15726 C CD  . GLU D 1 948 ? -0.686  2.860   26.789  1.00 113.85 ? 1023 GLU D CD  1 
ATOM   15727 O OE1 . GLU D 1 948 ? -1.496  1.954   27.070  1.00 126.64 ? 1023 GLU D OE1 1 
ATOM   15728 O OE2 . GLU D 1 948 ? 0.518   2.819   27.108  1.00 113.05 ? 1023 GLU D OE2 1 
ATOM   15729 N N   . LYS D 1 949 ? -2.820  3.673   21.671  1.00 115.79 ? 1024 LYS D N   1 
ATOM   15730 C CA  . LYS D 1 949 ? -2.674  3.392   20.245  1.00 110.76 ? 1024 LYS D CA  1 
ATOM   15731 C C   . LYS D 1 949 ? -2.578  4.673   19.420  1.00 113.62 ? 1024 LYS D C   1 
ATOM   15732 O O   . LYS D 1 949 ? -1.899  4.696   18.387  1.00 130.52 ? 1024 LYS D O   1 
ATOM   15733 C CB  . LYS D 1 949 ? -3.837  2.529   19.751  1.00 117.72 ? 1024 LYS D CB  1 
ATOM   15734 C CG  . LYS D 1 949 ? -3.693  2.061   18.311  1.00 132.25 ? 1024 LYS D CG  1 
ATOM   15735 C CD  . LYS D 1 949 ? -4.908  1.266   17.867  1.00 131.46 ? 1024 LYS D CD  1 
ATOM   15736 C CE  . LYS D 1 949 ? -4.685  0.620   16.509  1.00 137.97 ? 1024 LYS D CE  1 
ATOM   15737 N NZ  . LYS D 1 949 ? -4.389  1.632   15.457  1.00 139.01 ? 1024 LYS D NZ  1 
ATOM   15738 N N   . PHE D 1 950 ? -3.234  5.753   19.862  1.00 107.23 ? 1025 PHE D N   1 
ATOM   15739 C CA  . PHE D 1 950 ? -3.184  7.036   19.166  1.00 115.41 ? 1025 PHE D CA  1 
ATOM   15740 C C   . PHE D 1 950 ? -2.608  8.158   20.028  1.00 115.18 ? 1025 PHE D C   1 
ATOM   15741 O O   . PHE D 1 950 ? -2.765  9.333   19.681  1.00 108.38 ? 1025 PHE D O   1 
ATOM   15742 C CB  . PHE D 1 950 ? -4.572  7.455   18.672  1.00 121.11 ? 1025 PHE D CB  1 
ATOM   15743 C CG  . PHE D 1 950 ? -5.403  6.332   18.122  1.00 125.04 ? 1025 PHE D CG  1 
ATOM   15744 C CD1 . PHE D 1 950 ? -4.974  5.597   17.030  1.00 137.86 ? 1025 PHE D CD1 1 
ATOM   15745 C CD2 . PHE D 1 950 ? -6.636  6.034   18.682  1.00 121.57 ? 1025 PHE D CD2 1 
ATOM   15746 C CE1 . PHE D 1 950 ? -5.750  4.572   16.518  1.00 138.89 ? 1025 PHE D CE1 1 
ATOM   15747 C CE2 . PHE D 1 950 ? -7.416  5.012   18.177  1.00 127.28 ? 1025 PHE D CE2 1 
ATOM   15748 C CZ  . PHE D 1 950 ? -6.973  4.280   17.093  1.00 140.11 ? 1025 PHE D CZ  1 
ATOM   15749 N N   . MET D 1 951 ? -1.952  7.839   21.142  1.00 111.92 ? 1026 MET D N   1 
ATOM   15750 C CA  . MET D 1 951 ? -1.524  8.859   22.093  1.00 125.39 ? 1026 MET D CA  1 
ATOM   15751 C C   . MET D 1 951 ? -0.073  9.249   21.856  1.00 134.67 ? 1026 MET D C   1 
ATOM   15752 O O   . MET D 1 951 ? 0.804   8.384   21.759  1.00 136.64 ? 1026 MET D O   1 
ATOM   15753 C CB  . MET D 1 951 ? -1.698  8.388   23.538  1.00 128.45 ? 1026 MET D CB  1 
ATOM   15754 C CG  . MET D 1 951 ? -1.277  9.438   24.558  1.00 138.10 ? 1026 MET D CG  1 
ATOM   15755 S SD  . MET D 1 951 ? -2.018  9.242   26.191  1.00 134.86 ? 1026 MET D SD  1 
ATOM   15756 C CE  . MET D 1 951 ? -2.604  7.552   26.113  1.00 142.62 ? 1026 MET D CE  1 
ATOM   15757 N N   . THR D 1 952 ? 0.171   10.556  21.783  1.00 143.85 ? 1027 THR D N   1 
ATOM   15758 C CA  . THR D 1 952 ? 1.519   11.113  21.704  1.00 157.66 ? 1027 THR D CA  1 
ATOM   15759 C C   . THR D 1 952 ? 2.019   11.337  23.126  1.00 153.83 ? 1027 THR D C   1 
ATOM   15760 O O   . THR D 1 952 ? 1.678   12.334  23.767  1.00 157.48 ? 1027 THR D O   1 
ATOM   15761 C CB  . THR D 1 952 ? 1.516   12.409  20.901  1.00 163.27 ? 1027 THR D CB  1 
ATOM   15762 O OG1 . THR D 1 952 ? 0.409   13.222  21.311  1.00 148.41 ? 1027 THR D OG1 1 
ATOM   15763 C CG2 . THR D 1 952 ? 1.394   12.115  19.413  1.00 163.34 ? 1027 THR D CG2 1 
ATOM   15764 N N   . PHE D 1 953 ? 2.824   10.392  23.622  1.00 146.71 ? 1028 PHE D N   1 
ATOM   15765 C CA  . PHE D 1 953 ? 3.370   10.485  24.974  1.00 142.85 ? 1028 PHE D CA  1 
ATOM   15766 C C   . PHE D 1 953 ? 4.130   11.790  25.178  1.00 155.23 ? 1028 PHE D C   1 
ATOM   15767 O O   . PHE D 1 953 ? 3.927   12.498  26.176  1.00 160.28 ? 1028 PHE D O   1 
ATOM   15768 C CB  . PHE D 1 953 ? 4.275   9.280   25.235  1.00 115.71 ? 1028 PHE D CB  1 
ATOM   15769 C CG  . PHE D 1 953 ? 4.996   9.331   26.546  1.00 143.20 ? 1028 PHE D CG  1 
ATOM   15770 C CD1 . PHE D 1 953 ? 4.299   9.444   27.732  1.00 159.55 ? 1028 PHE D CD1 1 
ATOM   15771 C CD2 . PHE D 1 953 ? 6.377   9.259   26.592  1.00 158.76 ? 1028 PHE D CD2 1 
ATOM   15772 C CE1 . PHE D 1 953 ? 4.971   9.489   28.937  1.00 167.76 ? 1028 PHE D CE1 1 
ATOM   15773 C CE2 . PHE D 1 953 ? 7.050   9.303   27.796  1.00 137.97 ? 1028 PHE D CE2 1 
ATOM   15774 C CZ  . PHE D 1 953 ? 6.344   9.418   28.970  1.00 140.89 ? 1028 PHE D CZ  1 
ATOM   15775 N N   . GLN D 1 954 ? 5.017   12.118  24.234  1.00 163.30 ? 1029 GLN D N   1 
ATOM   15776 C CA  . GLN D 1 954 ? 5.769   13.368  24.294  1.00 165.15 ? 1029 GLN D CA  1 
ATOM   15777 C C   . GLN D 1 954 ? 4.839   14.566  24.436  1.00 172.83 ? 1029 GLN D C   1 
ATOM   15778 O O   . GLN D 1 954 ? 5.173   15.547  25.110  1.00 175.77 ? 1029 GLN D O   1 
ATOM   15779 C CB  . GLN D 1 954 ? 6.641   13.500  23.042  1.00 171.32 ? 1029 GLN D CB  1 
ATOM   15780 C CG  . GLN D 1 954 ? 5.913   14.055  21.817  1.00 184.25 ? 1029 GLN D CG  1 
ATOM   15781 C CD  . GLN D 1 954 ? 5.399   12.967  20.888  1.00 185.72 ? 1029 GLN D CD  1 
ATOM   15782 O OE1 . GLN D 1 954 ? 4.745   12.020  21.323  1.00 188.77 ? 1029 GLN D OE1 1 
ATOM   15783 N NE2 . GLN D 1 954 ? 5.688   13.105  19.598  1.00 186.71 ? 1029 GLN D NE2 1 
ATOM   15784 N N   . MET D 1 955 ? 3.660   14.497  23.817  1.00 177.02 ? 1030 MET D N   1 
ATOM   15785 C CA  . MET D 1 955 ? 2.670   15.554  23.930  1.00 176.74 ? 1030 MET D CA  1 
ATOM   15786 C C   . MET D 1 955 ? 1.692   15.312  25.069  1.00 163.37 ? 1030 MET D C   1 
ATOM   15787 O O   . MET D 1 955 ? 1.079   16.270  25.553  1.00 158.57 ? 1030 MET D O   1 
ATOM   15788 C CB  . MET D 1 955 ? 1.902   15.699  22.611  1.00 207.13 ? 1030 MET D CB  1 
ATOM   15789 C CG  . MET D 1 955 ? 2.654   16.434  21.501  1.00 209.18 ? 1030 MET D CG  1 
ATOM   15790 S SD  . MET D 1 955 ? 3.216   18.097  21.928  1.00 181.03 ? 1030 MET D SD  1 
ATOM   15791 C CE  . MET D 1 955 ? 4.933   17.800  22.344  1.00 179.85 ? 1030 MET D CE  1 
ATOM   15792 N N   . SER D 1 956 ? 1.529   14.056  25.497  1.00 160.81 ? 1031 SER D N   1 
ATOM   15793 C CA  . SER D 1 956 ? 0.747   13.781  26.697  1.00 154.04 ? 1031 SER D CA  1 
ATOM   15794 C C   . SER D 1 956 ? 1.354   14.476  27.905  1.00 150.54 ? 1031 SER D C   1 
ATOM   15795 O O   . SER D 1 956 ? 0.631   14.979  28.773  1.00 155.25 ? 1031 SER D O   1 
ATOM   15796 C CB  . SER D 1 956 ? 0.658   12.276  26.942  1.00 135.53 ? 1031 SER D CB  1 
ATOM   15797 O OG  . SER D 1 956 ? 1.843   11.795  27.552  1.00 124.71 ? 1031 SER D OG  1 
ATOM   15798 N N   . LEU D 1 957 ? 2.686   14.510  27.982  1.00 150.50 ? 1032 LEU D N   1 
ATOM   15799 C CA  . LEU D 1 957 ? 3.333   15.269  29.048  1.00 147.71 ? 1032 LEU D CA  1 
ATOM   15800 C C   . LEU D 1 957 ? 3.031   16.757  28.922  1.00 157.77 ? 1032 LEU D C   1 
ATOM   15801 O O   . LEU D 1 957 ? 2.704   17.423  29.912  1.00 158.58 ? 1032 LEU D O   1 
ATOM   15802 C CB  . LEU D 1 957 ? 4.840   15.016  29.044  1.00 124.35 ? 1032 LEU D CB  1 
ATOM   15803 C CG  . LEU D 1 957 ? 5.246   13.548  28.947  1.00 119.04 ? 1032 LEU D CG  1 
ATOM   15804 C CD1 . LEU D 1 957 ? 6.752   13.420  28.989  1.00 97.36  ? 1032 LEU D CD1 1 
ATOM   15805 C CD2 . LEU D 1 957 ? 4.607   12.766  30.082  1.00 127.76 ? 1032 LEU D CD2 1 
ATOM   15806 N N   . ARG D 1 958 ? 3.128   17.294  27.708  1.00 165.13 ? 1033 ARG D N   1 
ATOM   15807 C CA  . ARG D 1 958 ? 2.846   18.704  27.479  1.00 163.69 ? 1033 ARG D CA  1 
ATOM   15808 C C   . ARG D 1 958 ? 1.368   18.999  27.719  1.00 153.91 ? 1033 ARG D C   1 
ATOM   15809 O O   . ARG D 1 958 ? 0.507   18.127  27.583  1.00 155.85 ? 1033 ARG D O   1 
ATOM   15810 C CB  . ARG D 1 958 ? 3.243   19.099  26.052  1.00 164.38 ? 1033 ARG D CB  1 
ATOM   15811 C CG  . ARG D 1 958 ? 3.030   20.570  25.703  1.00 160.73 ? 1033 ARG D CG  1 
ATOM   15812 C CD  . ARG D 1 958 ? 3.221   20.824  24.215  1.00 169.20 ? 1033 ARG D CD  1 
ATOM   15813 N NE  . ARG D 1 958 ? 2.456   21.977  23.753  1.00 166.01 ? 1033 ARG D NE  1 
ATOM   15814 C CZ  . ARG D 1 958 ? 2.341   22.341  22.482  1.00 165.97 ? 1033 ARG D CZ  1 
ATOM   15815 N NH1 . ARG D 1 958 ? 2.924   21.656  21.512  1.00 161.63 ? 1033 ARG D NH1 1 
ATOM   15816 N NH2 . ARG D 1 958 ? 1.619   23.415  22.177  1.00 173.54 ? 1033 ARG D NH2 1 
ATOM   15817 N N   . ARG D 1 959 ? 1.082   20.245  28.094  1.00 148.88 ? 1034 ARG D N   1 
ATOM   15818 C CA  . ARG D 1 959 ? -0.286  20.671  28.356  1.00 150.35 ? 1034 ARG D CA  1 
ATOM   15819 C C   . ARG D 1 959 ? -0.589  21.978  27.630  1.00 148.08 ? 1034 ARG D C   1 
ATOM   15820 O O   . ARG D 1 959 ? -1.130  21.956  26.519  1.00 158.84 ? 1034 ARG D O   1 
ATOM   15821 C CB  . ARG D 1 959 ? -0.508  20.784  29.866  1.00 149.90 ? 1034 ARG D CB  1 
ATOM   15822 C CG  . ARG D 1 959 ? -0.547  19.411  30.536  1.00 148.73 ? 1034 ARG D CG  1 
ATOM   15823 C CD  . ARG D 1 959 ? -0.500  19.466  32.052  1.00 149.74 ? 1034 ARG D CD  1 
ATOM   15824 N NE  . ARG D 1 959 ? 0.712   20.113  32.535  1.00 142.09 ? 1034 ARG D NE  1 
ATOM   15825 C CZ  . ARG D 1 959 ? 0.942   20.425  33.803  1.00 155.21 ? 1034 ARG D CZ  1 
ATOM   15826 N NH1 . ARG D 1 959 ? 0.064   20.147  34.753  1.00 169.35 ? 1034 ARG D NH1 1 
ATOM   15827 N NH2 . ARG D 1 959 ? 2.088   21.018  34.128  1.00 143.19 ? 1034 ARG D NH2 1 
ATOM   15828 N N   . GLU D 1 960 ? -0.250  23.114  28.244  1.00 141.96 ? 1035 GLU D N   1 
ATOM   15829 C CA  . GLU D 1 960 ? -0.345  24.426  27.593  1.00 154.14 ? 1035 GLU D CA  1 
ATOM   15830 C C   . GLU D 1 960 ? -1.740  24.680  27.023  1.00 160.85 ? 1035 GLU D C   1 
ATOM   15831 O O   . GLU D 1 960 ? -1.892  25.234  25.931  1.00 162.44 ? 1035 GLU D O   1 
ATOM   15832 C CB  . GLU D 1 960 ? 0.712   24.570  26.496  1.00 152.10 ? 1035 GLU D CB  1 
ATOM   15833 C CG  . GLU D 1 960 ? 2.134   24.263  26.932  1.00 161.12 ? 1035 GLU D CG  1 
ATOM   15834 C CD  . GLU D 1 960 ? 3.130   24.411  25.796  1.00 158.55 ? 1035 GLU D CD  1 
ATOM   15835 O OE1 . GLU D 1 960 ? 2.703   24.746  24.671  1.00 158.70 ? 1035 GLU D OE1 1 
ATOM   15836 O OE2 . GLU D 1 960 ? 4.337   24.192  26.026  1.00 157.42 ? 1035 GLU D OE2 1 
ATOM   15837 N N   . ASP D 1 961 ? -2.765  24.242  27.759  1.00 158.22 ? 1036 ASP D N   1 
ATOM   15838 C CA  . ASP D 1 961 ? -4.169  24.443  27.403  1.00 155.44 ? 1036 ASP D CA  1 
ATOM   15839 C C   . ASP D 1 961 ? -4.594  23.659  26.162  1.00 148.90 ? 1036 ASP D C   1 
ATOM   15840 O O   . ASP D 1 961 ? -5.728  23.173  26.097  1.00 148.78 ? 1036 ASP D O   1 
ATOM   15841 C CB  . ASP D 1 961 ? -4.466  25.936  27.209  1.00 155.58 ? 1036 ASP D CB  1 
ATOM   15842 C CG  . ASP D 1 961 ? -5.800  26.182  26.536  1.00 152.22 ? 1036 ASP D CG  1 
ATOM   15843 O OD1 . ASP D 1 961 ? -6.840  25.821  27.125  1.00 172.54 ? 1036 ASP D OD1 1 
ATOM   15844 O OD2 . ASP D 1 961 ? -5.807  26.736  25.416  1.00 131.33 ? 1036 ASP D OD2 1 
ATOM   15845 N N   . VAL D 1 962 ? -3.708  23.530  25.171  1.00 144.54 ? 1037 VAL D N   1 
ATOM   15846 C CA  . VAL D 1 962 ? -4.070  22.819  23.947  1.00 135.59 ? 1037 VAL D CA  1 
ATOM   15847 C C   . VAL D 1 962 ? -4.255  21.332  24.223  1.00 142.06 ? 1037 VAL D C   1 
ATOM   15848 O O   . VAL D 1 962 ? -5.126  20.682  23.634  1.00 133.77 ? 1037 VAL D O   1 
ATOM   15849 C CB  . VAL D 1 962 ? -3.019  23.066  22.849  1.00 137.51 ? 1037 VAL D CB  1 
ATOM   15850 C CG1 . VAL D 1 962 ? -3.168  24.468  22.283  1.00 145.41 ? 1037 VAL D CG1 1 
ATOM   15851 C CG2 . VAL D 1 962 ? -1.614  22.855  23.393  1.00 147.64 ? 1037 VAL D CG2 1 
ATOM   15852 N N   . TRP D 1 963 ? -3.445  20.770  25.115  1.00 149.31 ? 1038 TRP D N   1 
ATOM   15853 C CA  . TRP D 1 963 ? -3.554  19.372  25.500  1.00 147.17 ? 1038 TRP D CA  1 
ATOM   15854 C C   . TRP D 1 963 ? -4.405  19.189  26.747  1.00 143.57 ? 1038 TRP D C   1 
ATOM   15855 O O   . TRP D 1 963 ? -4.502  18.071  27.264  1.00 157.98 ? 1038 TRP D O   1 
ATOM   15856 C CB  . TRP D 1 963 ? -2.159  18.780  25.710  1.00 160.35 ? 1038 TRP D CB  1 
ATOM   15857 C CG  . TRP D 1 963 ? -1.307  18.898  24.483  1.00 162.78 ? 1038 TRP D CG  1 
ATOM   15858 C CD1 . TRP D 1 963 ? -0.250  19.741  24.299  1.00 158.18 ? 1038 TRP D CD1 1 
ATOM   15859 C CD2 . TRP D 1 963 ? -1.453  18.165  23.261  1.00 155.64 ? 1038 TRP D CD2 1 
ATOM   15860 N NE1 . TRP D 1 963 ? 0.276   19.574  23.042  1.00 162.79 ? 1038 TRP D NE1 1 
ATOM   15861 C CE2 . TRP D 1 963 ? -0.444  18.612  22.385  1.00 159.13 ? 1038 TRP D CE2 1 
ATOM   15862 C CE3 . TRP D 1 963 ? -2.333  17.172  22.825  1.00 146.23 ? 1038 TRP D CE3 1 
ATOM   15863 C CZ2 . TRP D 1 963 ? -0.295  18.101  21.099  1.00 158.71 ? 1038 TRP D CZ2 1 
ATOM   15864 C CZ3 . TRP D 1 963 ? -2.180  16.665  21.551  1.00 137.85 ? 1038 TRP D CZ3 1 
ATOM   15865 C CH2 . TRP D 1 963 ? -1.169  17.129  20.703  1.00 141.65 ? 1038 TRP D CH2 1 
ATOM   15866 N N   . LEU D 1 964 ? -5.017  20.268  27.236  1.00 146.47 ? 1039 LEU D N   1 
ATOM   15867 C CA  . LEU D 1 964 ? -5.869  20.180  28.418  1.00 153.41 ? 1039 LEU D CA  1 
ATOM   15868 C C   . LEU D 1 964 ? -7.060  19.245  28.238  1.00 139.96 ? 1039 LEU D C   1 
ATOM   15869 O O   . LEU D 1 964 ? -7.378  18.517  29.194  1.00 135.09 ? 1039 LEU D O   1 
ATOM   15870 C CB  . LEU D 1 964 ? -6.328  21.587  28.824  1.00 163.05 ? 1039 LEU D CB  1 
ATOM   15871 C CG  . LEU D 1 964 ? -7.452  21.684  29.858  1.00 179.92 ? 1039 LEU D CG  1 
ATOM   15872 C CD1 . LEU D 1 964 ? -6.928  21.451  31.267  1.00 195.14 ? 1039 LEU D CD1 1 
ATOM   15873 C CD2 . LEU D 1 964 ? -8.154  23.031  29.757  1.00 172.64 ? 1039 LEU D CD2 1 
ATOM   15874 N N   . PRO D 1 965 ? -7.766  19.219  27.101  1.00 130.85 ? 1040 PRO D N   1 
ATOM   15875 C CA  . PRO D 1 965 ? -8.814  18.194  26.943  1.00 125.84 ? 1040 PRO D CA  1 
ATOM   15876 C C   . PRO D 1 965 ? -8.269  16.778  26.979  1.00 127.00 ? 1040 PRO D C   1 
ATOM   15877 O O   . PRO D 1 965 ? -8.871  15.898  27.610  1.00 129.88 ? 1040 PRO D O   1 
ATOM   15878 C CB  . PRO D 1 965 ? -9.429  18.543  25.581  1.00 113.67 ? 1040 PRO D CB  1 
ATOM   15879 C CG  . PRO D 1 965 ? -9.211  20.009  25.459  1.00 118.67 ? 1040 PRO D CG  1 
ATOM   15880 C CD  . PRO D 1 965 ? -7.834  20.217  26.017  1.00 136.51 ? 1040 PRO D CD  1 
ATOM   15881 N N   . LEU D 1 966 ? -7.137  16.535  26.313  1.00 120.41 ? 1041 LEU D N   1 
ATOM   15882 C CA  . LEU D 1 966 ? -6.506  15.221  26.373  1.00 128.61 ? 1041 LEU D CA  1 
ATOM   15883 C C   . LEU D 1 966 ? -6.125  14.861  27.803  1.00 128.15 ? 1041 LEU D C   1 
ATOM   15884 O O   . LEU D 1 966 ? -6.388  13.746  28.264  1.00 124.97 ? 1041 LEU D O   1 
ATOM   15885 C CB  . LEU D 1 966 ? -5.275  15.186  25.466  1.00 124.72 ? 1041 LEU D CB  1 
ATOM   15886 C CG  . LEU D 1 966 ? -4.378  13.958  25.641  1.00 120.45 ? 1041 LEU D CG  1 
ATOM   15887 C CD1 . LEU D 1 966 ? -4.941  12.759  24.886  1.00 114.84 ? 1041 LEU D CD1 1 
ATOM   15888 C CD2 . LEU D 1 966 ? -2.954  14.260  25.203  1.00 123.71 ? 1041 LEU D CD2 1 
ATOM   15889 N N   . MET D 1 967 ? -5.506  15.802  28.523  1.00 129.11 ? 1042 MET D N   1 
ATOM   15890 C CA  . MET D 1 967 ? -5.090  15.531  29.896  1.00 127.47 ? 1042 MET D CA  1 
ATOM   15891 C C   . MET D 1 967 ? -6.291  15.280  30.799  1.00 126.94 ? 1042 MET D C   1 
ATOM   15892 O O   . MET D 1 967 ? -6.243  14.416  31.682  1.00 132.28 ? 1042 MET D O   1 
ATOM   15893 C CB  . MET D 1 967 ? -4.250  16.695  30.426  1.00 139.72 ? 1042 MET D CB  1 
ATOM   15894 C CG  . MET D 1 967 ? -2.759  16.577  30.139  1.00 146.53 ? 1042 MET D CG  1 
ATOM   15895 S SD  . MET D 1 967 ? -1.979  15.167  30.951  1.00 184.69 ? 1042 MET D SD  1 
ATOM   15896 C CE  . MET D 1 967 ? -2.585  15.361  32.626  1.00 155.21 ? 1042 MET D CE  1 
ATOM   15897 N N   . SER D 1 968 ? -7.384  16.013  30.582  1.00 127.48 ? 1043 SER D N   1 
ATOM   15898 C CA  . SER D 1 968 ? -8.568  15.849  31.418  1.00 120.02 ? 1043 SER D CA  1 
ATOM   15899 C C   . SER D 1 968 ? -9.251  14.513  31.157  1.00 116.10 ? 1043 SER D C   1 
ATOM   15900 O O   . SER D 1 968 ? -9.651  13.822  32.101  1.00 122.95 ? 1043 SER D O   1 
ATOM   15901 C CB  . SER D 1 968 ? -9.538  17.007  31.182  1.00 119.37 ? 1043 SER D CB  1 
ATOM   15902 O OG  . SER D 1 968 ? -10.114 16.931  29.890  1.00 120.91 ? 1043 SER D OG  1 
ATOM   15903 N N   . TYR D 1 969 ? -9.397  14.131  29.884  1.00 103.45 ? 1044 TYR D N   1 
ATOM   15904 C CA  . TYR D 1 969 ? -9.946  12.814  29.573  1.00 108.33 ? 1044 TYR D CA  1 
ATOM   15905 C C   . TYR D 1 969 ? -9.051  11.706  30.113  1.00 107.16 ? 1044 TYR D C   1 
ATOM   15906 O O   . TYR D 1 969 ? -9.541  10.699  30.637  1.00 106.83 ? 1044 TYR D O   1 
ATOM   15907 C CB  . TYR D 1 969 ? -10.132 12.663  28.063  1.00 96.12  ? 1044 TYR D CB  1 
ATOM   15908 C CG  . TYR D 1 969 ? -10.577 11.280  27.644  1.00 95.66  ? 1044 TYR D CG  1 
ATOM   15909 C CD1 . TYR D 1 969 ? -11.814 10.782  28.027  1.00 101.88 ? 1044 TYR D CD1 1 
ATOM   15910 C CD2 . TYR D 1 969 ? -9.755  10.470  26.872  1.00 98.62  ? 1044 TYR D CD2 1 
ATOM   15911 C CE1 . TYR D 1 969 ? -12.223 9.518   27.647  1.00 103.99 ? 1044 TYR D CE1 1 
ATOM   15912 C CE2 . TYR D 1 969 ? -10.156 9.206   26.489  1.00 95.23  ? 1044 TYR D CE2 1 
ATOM   15913 C CZ  . TYR D 1 969 ? -11.390 8.735   26.879  1.00 95.97  ? 1044 TYR D CZ  1 
ATOM   15914 O OH  . TYR D 1 969 ? -11.792 7.476   26.500  1.00 93.33  ? 1044 TYR D OH  1 
ATOM   15915 N N   . ARG D 1 970 ? -7.734  11.885  30.001  1.00 123.46 ? 1045 ARG D N   1 
ATOM   15916 C CA  . ARG D 1 970 ? -6.778  10.905  30.502  1.00 124.89 ? 1045 ARG D CA  1 
ATOM   15917 C C   . ARG D 1 970 ? -6.871  10.745  32.017  1.00 127.35 ? 1045 ARG D C   1 
ATOM   15918 O O   . ARG D 1 970 ? -6.798  9.624   32.536  1.00 133.04 ? 1045 ARG D O   1 
ATOM   15919 C CB  . ARG D 1 970 ? -5.377  11.331  30.067  1.00 123.57 ? 1045 ARG D CB  1 
ATOM   15920 C CG  . ARG D 1 970 ? -4.246  10.723  30.841  1.00 133.73 ? 1045 ARG D CG  1 
ATOM   15921 C CD  . ARG D 1 970 ? -2.928  11.223  30.291  1.00 111.50 ? 1045 ARG D CD  1 
ATOM   15922 N NE  . ARG D 1 970 ? -1.808  10.582  30.960  1.00 108.65 ? 1045 ARG D NE  1 
ATOM   15923 C CZ  . ARG D 1 970 ? -0.862  11.251  31.602  1.00 137.89 ? 1045 ARG D CZ  1 
ATOM   15924 N NH1 . ARG D 1 970 ? -0.815  12.574  31.578  1.00 149.62 ? 1045 ARG D NH1 1 
ATOM   15925 N NH2 . ARG D 1 970 ? 0.043   10.580  32.303  1.00 146.96 ? 1045 ARG D NH2 1 
ATOM   15926 N N   . ASN D 1 971 ? -7.027  11.854  32.745  1.00 132.30 ? 1046 ASN D N   1 
ATOM   15927 C CA  . ASN D 1 971 ? -7.229  11.764  34.188  1.00 126.92 ? 1046 ASN D CA  1 
ATOM   15928 C C   . ASN D 1 971 ? -8.582  11.145  34.512  1.00 118.51 ? 1046 ASN D C   1 
ATOM   15929 O O   . ASN D 1 971 ? -8.719  10.422  35.505  1.00 120.38 ? 1046 ASN D O   1 
ATOM   15930 C CB  . ASN D 1 971 ? -7.107  13.148  34.825  1.00 122.71 ? 1046 ASN D CB  1 
ATOM   15931 C CG  . ASN D 1 971 ? -5.719  13.738  34.682  1.00 129.08 ? 1046 ASN D CG  1 
ATOM   15932 O OD1 . ASN D 1 971 ? -4.821  13.117  34.115  1.00 144.38 ? 1046 ASN D OD1 1 
ATOM   15933 N ND2 . ASN D 1 971 ? -5.537  14.949  35.197  1.00 127.21 ? 1046 ASN D ND2 1 
ATOM   15934 N N   . SER D 1 972 ? -9.594  11.418  33.684  1.00 112.05 ? 1047 SER D N   1 
ATOM   15935 C CA  . SER D 1 972 ? -10.910 10.824  33.890  1.00 109.49 ? 1047 SER D CA  1 
ATOM   15936 C C   . SER D 1 972 ? -10.878 9.311   33.746  1.00 118.12 ? 1047 SER D C   1 
ATOM   15937 O O   . SER D 1 972 ? -11.755 8.627   34.284  1.00 107.47 ? 1047 SER D O   1 
ATOM   15938 C CB  . SER D 1 972 ? -11.916 11.419  32.904  1.00 95.14  ? 1047 SER D CB  1 
ATOM   15939 O OG  . SER D 1 972 ? -11.888 12.835  32.936  1.00 101.78 ? 1047 SER D OG  1 
ATOM   15940 N N   . LEU D 1 973 ? -9.889  8.776   33.032  1.00 124.53 ? 1048 LEU D N   1 
ATOM   15941 C CA  . LEU D 1 973 ? -9.742  7.338   32.868  1.00 128.17 ? 1048 LEU D CA  1 
ATOM   15942 C C   . LEU D 1 973 ? -9.026  6.677   34.038  1.00 128.72 ? 1048 LEU D C   1 
ATOM   15943 O O   . LEU D 1 973 ? -8.844  5.455   34.016  1.00 137.49 ? 1048 LEU D O   1 
ATOM   15944 C CB  . LEU D 1 973 ? -8.994  7.034   31.568  1.00 123.02 ? 1048 LEU D CB  1 
ATOM   15945 C CG  . LEU D 1 973 ? -9.650  7.537   30.281  1.00 147.43 ? 1048 LEU D CG  1 
ATOM   15946 C CD1 . LEU D 1 973 ? -8.903  7.029   29.054  1.00 149.94 ? 1048 LEU D CD1 1 
ATOM   15947 C CD2 . LEU D 1 973 ? -11.119 7.145   30.231  1.00 164.63 ? 1048 LEU D CD2 1 
ATOM   15948 N N   . LEU D 1 974 ? -8.608  7.441   35.047  1.00 131.57 ? 1049 LEU D N   1 
ATOM   15949 C CA  . LEU D 1 974 ? -7.998  6.844   36.228  1.00 131.18 ? 1049 LEU D CA  1 
ATOM   15950 C C   . LEU D 1 974 ? -9.016  5.974   36.953  1.00 123.33 ? 1049 LEU D C   1 
ATOM   15951 O O   . LEU D 1 974 ? -10.119 6.426   37.276  1.00 129.16 ? 1049 LEU D O   1 
ATOM   15952 C CB  . LEU D 1 974 ? -7.463  7.932   37.159  1.00 121.70 ? 1049 LEU D CB  1 
ATOM   15953 C CG  . LEU D 1 974 ? -6.215  8.679   36.680  1.00 124.66 ? 1049 LEU D CG  1 
ATOM   15954 C CD1 . LEU D 1 974 ? -5.664  9.571   37.779  1.00 120.25 ? 1049 LEU D CD1 1 
ATOM   15955 C CD2 . LEU D 1 974 ? -5.155  7.702   36.196  1.00 135.93 ? 1049 LEU D CD2 1 
ATOM   15956 N N   . ALA D 1 975 ? -8.639  4.719   37.200  1.00 114.89 ? 1050 ALA D N   1 
ATOM   15957 C CA  . ALA D 1 975 ? -9.569  3.746   37.757  1.00 110.94 ? 1050 ALA D CA  1 
ATOM   15958 C C   . ALA D 1 975 ? -10.106 4.210   39.105  1.00 143.40 ? 1050 ALA D C   1 
ATOM   15959 O O   . ALA D 1 975 ? -9.391  4.822   39.903  1.00 154.81 ? 1050 ALA D O   1 
ATOM   15960 C CB  . ALA D 1 975 ? -8.886  2.386   37.904  1.00 101.38 ? 1050 ALA D CB  1 
ATOM   15961 N N   . GLY D 1 976 ? -11.382 3.921   39.348  1.00 148.96 ? 1051 GLY D N   1 
ATOM   15962 C CA  . GLY D 1 976 ? -12.013 4.225   40.612  1.00 144.96 ? 1051 GLY D CA  1 
ATOM   15963 C C   . GLY D 1 976 ? -11.704 3.261   41.732  1.00 143.94 ? 1051 GLY D C   1 
ATOM   15964 O O   . GLY D 1 976 ? -12.249 3.407   42.829  1.00 147.19 ? 1051 GLY D O   1 
ATOM   15965 N N   . GLY D 1 977 ? -10.843 2.277   41.489  1.00 137.97 ? 1052 GLY D N   1 
ATOM   15966 C CA  . GLY D 1 977 ? -10.472 1.322   42.518  1.00 140.18 ? 1052 GLY D CA  1 
ATOM   15967 C C   . GLY D 1 977 ? -11.637 0.454   42.941  1.00 147.81 ? 1052 GLY D C   1 
ATOM   15968 O O   . GLY D 1 977 ? -12.168 -0.322  42.141  1.00 154.83 ? 1052 GLY D O   1 
ATOM   15969 N N   . ASP D 1 978 ? -12.038 0.579   44.207  1.00 151.36 ? 1053 ASP D N   1 
ATOM   15970 C CA  . ASP D 1 978 ? -13.199 -0.159  44.694  1.00 148.51 ? 1053 ASP D CA  1 
ATOM   15971 C C   . ASP D 1 978 ? -14.461 0.262   43.950  1.00 153.44 ? 1053 ASP D C   1 
ATOM   15972 O O   . ASP D 1 978 ? -15.189 -0.579  43.409  1.00 138.31 ? 1053 ASP D O   1 
ATOM   15973 C CB  . ASP D 1 978 ? -13.354 0.057   46.200  1.00 140.84 ? 1053 ASP D CB  1 
ATOM   15974 C CG  . ASP D 1 978 ? -14.564 -0.649  46.771  1.00 139.46 ? 1053 ASP D CG  1 
ATOM   15975 O OD1 . ASP D 1 978 ? -14.640 -1.889  46.654  1.00 133.91 ? 1053 ASP D OD1 1 
ATOM   15976 O OD2 . ASP D 1 978 ? -15.438 0.038   47.340  1.00 123.82 ? 1053 ASP D OD2 1 
ATOM   15977 N N   . ASP D 1 979 ? -14.731 1.563   43.908  1.00 158.21 ? 1054 ASP D N   1 
ATOM   15978 C CA  . ASP D 1 979 ? -15.862 2.094   43.157  1.00 143.15 ? 1054 ASP D CA  1 
ATOM   15979 C C   . ASP D 1 979 ? -15.538 3.474   42.591  1.00 144.03 ? 1054 ASP D C   1 
ATOM   15980 O O   . ASP D 1 979 ? -15.194 3.607   41.416  1.00 144.92 ? 1054 ASP D O   1 
ATOM   15981 C CB  . ASP D 1 979 ? -17.114 2.159   44.033  1.00 133.43 ? 1054 ASP D CB  1 
ATOM   15982 C CG  . ASP D 1 979 ? -17.752 0.799   44.242  1.00 142.91 ? 1054 ASP D CG  1 
ATOM   15983 O OD1 . ASP D 1 979 ? -18.138 0.162   43.239  1.00 142.83 ? 1054 ASP D OD1 1 
ATOM   15984 O OD2 . ASP D 1 979 ? -17.862 0.362   45.407  1.00 155.70 ? 1054 ASP D OD2 1 
ATOM   15985 N N   . LYS E 2 44  ? -20.188 14.519  69.742  1.00 82.19  ? 321  LYS E N   1 
ATOM   15986 C CA  . LYS E 2 44  ? -20.790 15.829  69.518  1.00 91.96  ? 321  LYS E CA  1 
ATOM   15987 C C   . LYS E 2 44  ? -22.273 15.813  69.874  1.00 101.84 ? 321  LYS E C   1 
ATOM   15988 O O   . LYS E 2 44  ? -22.980 14.849  69.580  1.00 99.87  ? 321  LYS E O   1 
ATOM   15989 C CB  . LYS E 2 44  ? -20.600 16.265  68.064  1.00 110.82 ? 321  LYS E CB  1 
ATOM   15990 C CG  . LYS E 2 44  ? -20.946 17.721  67.801  1.00 130.77 ? 321  LYS E CG  1 
ATOM   15991 C CD  . LYS E 2 44  ? -20.639 18.108  66.365  1.00 147.99 ? 321  LYS E CD  1 
ATOM   15992 C CE  . LYS E 2 44  ? -20.951 19.570  66.098  1.00 168.96 ? 321  LYS E CE  1 
ATOM   15993 N NZ  . LYS E 2 44  ? -20.125 20.481  66.936  1.00 178.57 ? 321  LYS E NZ  1 
ATOM   15994 N N   . ARG E 2 45  ? -22.737 16.886  70.512  1.00 109.06 ? 322  ARG E N   1 
ATOM   15995 C CA  . ARG E 2 45  ? -24.140 16.987  70.892  1.00 94.95  ? 322  ARG E CA  1 
ATOM   15996 C C   . ARG E 2 45  ? -25.020 17.099  69.654  1.00 92.26  ? 322  ARG E C   1 
ATOM   15997 O O   . ARG E 2 45  ? -24.751 17.902  68.754  1.00 97.43  ? 322  ARG E O   1 
ATOM   15998 C CB  . ARG E 2 45  ? -24.355 18.189  71.810  1.00 103.33 ? 322  ARG E CB  1 
ATOM   15999 C CG  . ARG E 2 45  ? -23.621 18.091  73.137  1.00 96.59  ? 322  ARG E CG  1 
ATOM   16000 C CD  . ARG E 2 45  ? -24.217 17.004  74.020  1.00 89.42  ? 322  ARG E CD  1 
ATOM   16001 N NE  . ARG E 2 45  ? -25.658 17.160  74.179  1.00 93.18  ? 322  ARG E NE  1 
ATOM   16002 C CZ  . ARG E 2 45  ? -26.295 17.081  75.340  1.00 85.60  ? 322  ARG E CZ  1 
ATOM   16003 N NH1 . ARG E 2 45  ? -25.648 16.838  76.468  1.00 80.84  ? 322  ARG E NH1 1 
ATOM   16004 N NH2 . ARG E 2 45  ? -27.613 17.251  75.369  1.00 92.87  ? 322  ARG E NH2 1 
ATOM   16005 N N   . LYS E 2 46  ? -26.073 16.287  69.611  1.00 97.48  ? 323  LYS E N   1 
ATOM   16006 C CA  . LYS E 2 46  ? -27.015 16.274  68.501  1.00 96.08  ? 323  LYS E CA  1 
ATOM   16007 C C   . LYS E 2 46  ? -28.355 16.897  68.864  1.00 90.04  ? 323  LYS E C   1 
ATOM   16008 O O   . LYS E 2 46  ? -29.241 16.975  68.004  1.00 77.59  ? 323  LYS E O   1 
ATOM   16009 C CB  . LYS E 2 46  ? -27.229 14.835  68.016  1.00 86.20  ? 323  LYS E CB  1 
ATOM   16010 C CG  . LYS E 2 46  ? -25.943 14.041  67.834  1.00 95.76  ? 323  LYS E CG  1 
ATOM   16011 C CD  . LYS E 2 46  ? -25.078 14.604  66.715  1.00 97.34  ? 323  LYS E CD  1 
ATOM   16012 C CE  . LYS E 2 46  ? -25.755 14.440  65.367  1.00 95.48  ? 323  LYS E CE  1 
ATOM   16013 N NZ  . LYS E 2 46  ? -26.197 13.036  65.151  1.00 79.16  ? 323  LYS E NZ  1 
ATOM   16014 N N   . LEU E 2 47  ? -28.520 17.346  70.108  1.00 84.51  ? 324  LEU E N   1 
ATOM   16015 C CA  . LEU E 2 47  ? -29.792 17.886  70.570  1.00 77.62  ? 324  LEU E CA  1 
ATOM   16016 C C   . LEU E 2 47  ? -30.198 19.102  69.747  1.00 79.13  ? 324  LEU E C   1 
ATOM   16017 O O   . LEU E 2 47  ? -29.380 19.980  69.456  1.00 89.57  ? 324  LEU E O   1 
ATOM   16018 C CB  . LEU E 2 47  ? -29.689 18.260  72.049  1.00 67.93  ? 324  LEU E CB  1 
ATOM   16019 C CG  . LEU E 2 47  ? -30.909 18.904  72.702  1.00 68.01  ? 324  LEU E CG  1 
ATOM   16020 C CD1 . LEU E 2 47  ? -32.060 17.915  72.724  1.00 81.54  ? 324  LEU E CD1 1 
ATOM   16021 C CD2 . LEU E 2 47  ? -30.571 19.379  74.105  1.00 59.42  ? 324  LEU E CD2 1 
ATOM   16022 N N   . ILE E 2 48  ? -31.473 19.150  69.372  1.00 74.24  ? 325  ILE E N   1 
ATOM   16023 C CA  . ILE E 2 48  ? -31.991 20.225  68.532  1.00 68.22  ? 325  ILE E CA  1 
ATOM   16024 C C   . ILE E 2 48  ? -32.304 21.425  69.419  1.00 68.99  ? 325  ILE E C   1 
ATOM   16025 O O   . ILE E 2 48  ? -33.198 21.370  70.267  1.00 79.43  ? 325  ILE E O   1 
ATOM   16026 C CB  . ILE E 2 48  ? -33.229 19.781  67.745  1.00 60.60  ? 325  ILE E CB  1 
ATOM   16027 C CG1 . ILE E 2 48  ? -33.042 18.360  67.212  1.00 56.20  ? 325  ILE E CG1 1 
ATOM   16028 C CG2 . ILE E 2 48  ? -33.509 20.751  66.606  1.00 46.16  ? 325  ILE E CG2 1 
ATOM   16029 C CD1 . ILE E 2 48  ? -34.036 17.975  66.138  1.00 53.01  ? 325  ILE E CD1 1 
ATOM   16030 N N   . VAL E 2 49  ? -31.566 22.513  69.220  1.00 61.15  ? 326  VAL E N   1 
ATOM   16031 C CA  . VAL E 2 49  ? -31.805 23.781  69.898  1.00 65.99  ? 326  VAL E CA  1 
ATOM   16032 C C   . VAL E 2 49  ? -32.078 24.830  68.831  1.00 71.24  ? 326  VAL E C   1 
ATOM   16033 O O   . VAL E 2 49  ? -31.221 25.092  67.977  1.00 88.58  ? 326  VAL E O   1 
ATOM   16034 C CB  . VAL E 2 49  ? -30.618 24.191  70.783  1.00 66.53  ? 326  VAL E CB  1 
ATOM   16035 C CG1 . VAL E 2 49  ? -30.949 25.447  71.566  1.00 59.39  ? 326  VAL E CG1 1 
ATOM   16036 C CG2 . VAL E 2 49  ? -30.249 23.060  71.727  1.00 55.75  ? 326  VAL E CG2 1 
ATOM   16037 N N   . ASP E 2 50  ? -33.269 25.420  68.870  1.00 74.06  ? 327  ASP E N   1 
ATOM   16038 C CA  . ASP E 2 50  ? -33.644 26.470  67.932  1.00 80.22  ? 327  ASP E CA  1 
ATOM   16039 C C   . ASP E 2 50  ? -33.214 27.816  68.503  1.00 83.96  ? 327  ASP E C   1 
ATOM   16040 O O   . ASP E 2 50  ? -33.694 28.227  69.566  1.00 68.21  ? 327  ASP E O   1 
ATOM   16041 C CB  . ASP E 2 50  ? -35.147 26.450  67.658  1.00 69.62  ? 327  ASP E CB  1 
ATOM   16042 C CG  . ASP E 2 50  ? -35.662 25.058  67.348  1.00 83.22  ? 327  ASP E CG  1 
ATOM   16043 O OD1 . ASP E 2 50  ? -35.401 24.133  68.143  1.00 99.37  ? 327  ASP E OD1 1 
ATOM   16044 O OD2 . ASP E 2 50  ? -36.326 24.888  66.303  1.00 76.08  ? 327  ASP E OD2 1 
ATOM   16045 N N   . SER E 2 51  ? -32.299 28.492  67.803  1.00 89.80  ? 328  SER E N   1 
ATOM   16046 C CA  . SER E 2 51  ? -31.844 29.803  68.253  1.00 84.13  ? 328  SER E CA  1 
ATOM   16047 C C   . SER E 2 51  ? -32.990 30.806  68.267  1.00 83.60  ? 328  SER E C   1 
ATOM   16048 O O   . SER E 2 51  ? -33.083 31.643  69.173  1.00 73.85  ? 328  SER E O   1 
ATOM   16049 C CB  . SER E 2 51  ? -30.707 30.298  67.360  1.00 82.43  ? 328  SER E CB  1 
ATOM   16050 O OG  . SER E 2 51  ? -29.535 29.528  67.558  1.00 106.20 ? 328  SER E OG  1 
ATOM   16051 N N   . VAL E 2 52  ? -33.871 30.735  67.275  1.00 89.07  ? 329  VAL E N   1 
ATOM   16052 C CA  . VAL E 2 52  ? -35.057 31.577  67.200  1.00 83.15  ? 329  VAL E CA  1 
ATOM   16053 C C   . VAL E 2 52  ? -36.266 30.665  67.354  1.00 83.76  ? 329  VAL E C   1 
ATOM   16054 O O   . VAL E 2 52  ? -36.533 29.821  66.488  1.00 81.77  ? 329  VAL E O   1 
ATOM   16055 C CB  . VAL E 2 52  ? -35.114 32.365  65.884  1.00 75.86  ? 329  VAL E CB  1 
ATOM   16056 C CG1 . VAL E 2 52  ? -36.365 33.224  65.835  1.00 91.72  ? 329  VAL E CG1 1 
ATOM   16057 C CG2 . VAL E 2 52  ? -33.864 33.216  65.726  1.00 69.35  ? 329  VAL E CG2 1 
ATOM   16058 N N   . LYS E 2 53  ? -36.994 30.824  68.460  1.00 81.18  ? 330  LYS E N   1 
ATOM   16059 C CA  . LYS E 2 53  ? -38.154 29.985  68.734  1.00 76.28  ? 330  LYS E CA  1 
ATOM   16060 C C   . LYS E 2 53  ? -39.456 30.574  68.215  1.00 76.93  ? 330  LYS E C   1 
ATOM   16061 O O   . LYS E 2 53  ? -40.449 29.846  68.109  1.00 78.86  ? 330  LYS E O   1 
ATOM   16062 C CB  . LYS E 2 53  ? -38.302 29.748  70.242  1.00 69.90  ? 330  LYS E CB  1 
ATOM   16063 C CG  . LYS E 2 53  ? -37.028 29.356  70.964  1.00 75.85  ? 330  LYS E CG  1 
ATOM   16064 C CD  . LYS E 2 53  ? -37.155 29.654  72.450  1.00 65.62  ? 330  LYS E CD  1 
ATOM   16065 C CE  . LYS E 2 53  ? -37.398 31.134  72.694  1.00 74.18  ? 330  LYS E CE  1 
ATOM   16066 N NZ  . LYS E 2 53  ? -37.150 31.518  74.111  1.00 82.77  ? 330  LYS E NZ  1 
ATOM   16067 N N   . GLU E 2 54  ? -39.475 31.862  67.885  1.00 72.58  ? 331  GLU E N   1 
ATOM   16068 C CA  . GLU E 2 54  ? -40.711 32.594  67.659  1.00 67.97  ? 331  GLU E CA  1 
ATOM   16069 C C   . GLU E 2 54  ? -40.623 33.393  66.368  1.00 71.60  ? 331  GLU E C   1 
ATOM   16070 O O   . GLU E 2 54  ? -39.569 33.948  66.042  1.00 90.02  ? 331  GLU E O   1 
ATOM   16071 C CB  . GLU E 2 54  ? -40.990 33.531  68.841  1.00 80.05  ? 331  GLU E CB  1 
ATOM   16072 C CG  . GLU E 2 54  ? -42.420 34.018  68.966  1.00 79.14  ? 331  GLU E CG  1 
ATOM   16073 C CD  . GLU E 2 54  ? -42.601 34.961  70.140  1.00 84.54  ? 331  GLU E CD  1 
ATOM   16074 O OE1 . GLU E 2 54  ? -42.811 34.471  71.270  1.00 89.44  ? 331  GLU E OE1 1 
ATOM   16075 O OE2 . GLU E 2 54  ? -42.534 36.191  69.934  1.00 80.78  ? 331  GLU E OE2 1 
ATOM   16076 N N   . LEU E 2 55  ? -41.734 33.448  65.637  1.00 53.72  ? 332  LEU E N   1 
ATOM   16077 C CA  . LEU E 2 55  ? -41.823 34.328  64.480  1.00 51.95  ? 332  LEU E CA  1 
ATOM   16078 C C   . LEU E 2 55  ? -41.974 35.771  64.946  1.00 68.90  ? 332  LEU E C   1 
ATOM   16079 O O   . LEU E 2 55  ? -42.874 36.089  65.730  1.00 82.83  ? 332  LEU E O   1 
ATOM   16080 C CB  . LEU E 2 55  ? -43.004 33.937  63.591  1.00 53.91  ? 332  LEU E CB  1 
ATOM   16081 C CG  . LEU E 2 55  ? -43.074 32.516  63.025  1.00 44.55  ? 332  LEU E CG  1 
ATOM   16082 C CD1 . LEU E 2 55  ? -44.058 32.454  61.866  1.00 37.16  ? 332  LEU E CD1 1 
ATOM   16083 C CD2 . LEU E 2 55  ? -41.705 32.036  62.587  1.00 40.59  ? 332  LEU E CD2 1 
ATOM   16084 N N   . ASP E 2 56  ? -41.090 36.646  64.472  1.00 73.71  ? 333  ASP E N   1 
ATOM   16085 C CA  . ASP E 2 56  ? -41.165 38.044  64.865  1.00 77.95  ? 333  ASP E CA  1 
ATOM   16086 C C   . ASP E 2 56  ? -42.415 38.694  64.276  1.00 76.08  ? 333  ASP E C   1 
ATOM   16087 O O   . ASP E 2 56  ? -42.987 38.226  63.287  1.00 72.70  ? 333  ASP E O   1 
ATOM   16088 C CB  . ASP E 2 56  ? -39.912 38.798  64.419  1.00 74.45  ? 333  ASP E CB  1 
ATOM   16089 C CG  . ASP E 2 56  ? -39.589 38.577  62.958  1.00 80.74  ? 333  ASP E CG  1 
ATOM   16090 O OD1 . ASP E 2 56  ? -39.291 37.425  62.580  1.00 82.33  ? 333  ASP E OD1 1 
ATOM   16091 O OD2 . ASP E 2 56  ? -39.637 39.557  62.187  1.00 90.52  ? 333  ASP E OD2 1 
ATOM   16092 N N   . SER E 2 57  ? -42.844 39.789  64.910  1.00 73.13  ? 334  SER E N   1 
ATOM   16093 C CA  . SER E 2 57  ? -44.051 40.475  64.461  1.00 64.76  ? 334  SER E CA  1 
ATOM   16094 C C   . SER E 2 57  ? -43.889 41.047  63.060  1.00 71.03  ? 334  SER E C   1 
ATOM   16095 O O   . SER E 2 57  ? -44.874 41.166  62.327  1.00 69.09  ? 334  SER E O   1 
ATOM   16096 C CB  . SER E 2 57  ? -44.427 41.586  65.442  1.00 67.72  ? 334  SER E CB  1 
ATOM   16097 O OG  . SER E 2 57  ? -44.719 41.059  66.723  1.00 79.44  ? 334  SER E OG  1 
ATOM   16098 N N   . LYS E 2 58  ? -42.664 41.410  62.672  1.00 77.31  ? 335  LYS E N   1 
ATOM   16099 C CA  . LYS E 2 58  ? -42.435 41.901  61.317  1.00 77.42  ? 335  LYS E CA  1 
ATOM   16100 C C   . LYS E 2 58  ? -42.748 40.826  60.284  1.00 77.13  ? 335  LYS E C   1 
ATOM   16101 O O   . LYS E 2 58  ? -43.423 41.089  59.280  1.00 70.10  ? 335  LYS E O   1 
ATOM   16102 C CB  . LYS E 2 58  ? -40.992 42.388  61.170  1.00 76.09  ? 335  LYS E CB  1 
ATOM   16103 C CG  . LYS E 2 58  ? -40.727 43.216  59.914  1.00 84.95  ? 335  LYS E CG  1 
ATOM   16104 C CD  . LYS E 2 58  ? -41.937 44.041  59.486  1.00 94.48  ? 335  LYS E CD  1 
ATOM   16105 C CE  . LYS E 2 58  ? -42.051 45.329  60.287  1.00 94.79  ? 335  LYS E CE  1 
ATOM   16106 N NZ  . LYS E 2 58  ? -43.267 46.104  59.918  1.00 88.02  ? 335  LYS E NZ  1 
ATOM   16107 N N   . THR E 2 59  ? -42.266 39.602  60.516  1.00 67.88  ? 336  THR E N   1 
ATOM   16108 C CA  . THR E 2 59  ? -42.553 38.514  59.587  1.00 72.76  ? 336  THR E CA  1 
ATOM   16109 C C   . THR E 2 59  ? -44.033 38.158  59.578  1.00 75.72  ? 336  THR E C   1 
ATOM   16110 O O   . THR E 2 59  ? -44.570 37.785  58.531  1.00 68.35  ? 336  THR E O   1 
ATOM   16111 C CB  . THR E 2 59  ? -41.716 37.285  59.936  1.00 56.08  ? 336  THR E CB  1 
ATOM   16112 O OG1 . THR E 2 59  ? -41.739 37.077  61.353  1.00 80.00  ? 336  THR E OG1 1 
ATOM   16113 C CG2 . THR E 2 59  ? -40.280 37.471  59.475  1.00 64.07  ? 336  THR E CG2 1 
ATOM   16114 N N   . ILE E 2 60  ? -44.709 38.274  60.721  1.00 78.25  ? 337  ILE E N   1 
ATOM   16115 C CA  . ILE E 2 60  ? -46.144 38.007  60.761  1.00 67.72  ? 337  ILE E CA  1 
ATOM   16116 C C   . ILE E 2 60  ? -46.899 39.059  59.955  1.00 69.27  ? 337  ILE E C   1 
ATOM   16117 O O   . ILE E 2 60  ? -47.797 38.737  59.168  1.00 75.71  ? 337  ILE E O   1 
ATOM   16118 C CB  . ILE E 2 60  ? -46.637 37.942  62.217  1.00 57.99  ? 337  ILE E CB  1 
ATOM   16119 C CG1 . ILE E 2 60  ? -45.960 36.780  62.949  1.00 56.53  ? 337  ILE E CG1 1 
ATOM   16120 C CG2 . ILE E 2 60  ? -48.152 37.814  62.262  1.00 49.50  ? 337  ILE E CG2 1 
ATOM   16121 C CD1 . ILE E 2 60  ? -46.436 36.581  64.370  1.00 68.97  ? 337  ILE E CD1 1 
ATOM   16122 N N   . ARG E 2 61  ? -46.537 40.331  60.138  1.00 67.58  ? 338  ARG E N   1 
ATOM   16123 C CA  . ARG E 2 61  ? -47.128 41.402  59.343  1.00 69.86  ? 338  ARG E CA  1 
ATOM   16124 C C   . ARG E 2 61  ? -46.875 41.186  57.858  1.00 81.57  ? 338  ARG E C   1 
ATOM   16125 O O   . ARG E 2 61  ? -47.738 41.480  57.024  1.00 74.97  ? 338  ARG E O   1 
ATOM   16126 C CB  . ARG E 2 61  ? -46.557 42.751  59.779  1.00 76.75  ? 338  ARG E CB  1 
ATOM   16127 C CG  . ARG E 2 61  ? -46.919 43.180  61.186  1.00 73.66  ? 338  ARG E CG  1 
ATOM   16128 C CD  . ARG E 2 61  ? -45.959 44.265  61.665  1.00 85.15  ? 338  ARG E CD  1 
ATOM   16129 N NE  . ARG E 2 61  ? -46.073 44.536  63.094  1.00 92.65  ? 338  ARG E NE  1 
ATOM   16130 C CZ  . ARG E 2 61  ? -47.117 45.109  63.677  1.00 97.65  ? 338  ARG E CZ  1 
ATOM   16131 N NH1 . ARG E 2 61  ? -48.159 45.528  62.977  1.00 82.50  ? 338  ARG E NH1 1 
ATOM   16132 N NH2 . ARG E 2 61  ? -47.114 45.269  64.998  1.00 103.86 ? 338  ARG E NH2 1 
ATOM   16133 N N   . ALA E 2 62  ? -45.687 40.687  57.508  1.00 68.02  ? 339  ALA E N   1 
ATOM   16134 C CA  . ALA E 2 62  ? -45.380 40.430  56.105  1.00 71.44  ? 339  ALA E CA  1 
ATOM   16135 C C   . ALA E 2 62  ? -46.215 39.279  55.558  1.00 73.94  ? 339  ALA E C   1 
ATOM   16136 O O   . ALA E 2 62  ? -46.695 39.337  54.419  1.00 79.53  ? 339  ALA E O   1 
ATOM   16137 C CB  . ALA E 2 62  ? -43.889 40.141  55.943  1.00 79.41  ? 339  ALA E CB  1 
ATOM   16138 N N   . GLN E 2 63  ? -46.390 38.222  56.353  1.00 65.92  ? 340  GLN E N   1 
ATOM   16139 C CA  . GLN E 2 63  ? -47.266 37.126  55.958  1.00 63.03  ? 340  GLN E CA  1 
ATOM   16140 C C   . GLN E 2 63  ? -48.688 37.622  55.728  1.00 67.81  ? 340  GLN E C   1 
ATOM   16141 O O   . GLN E 2 63  ? -49.367 37.178  54.794  1.00 67.75  ? 340  GLN E O   1 
ATOM   16142 C CB  . GLN E 2 63  ? -47.247 36.036  57.030  1.00 54.04  ? 340  GLN E CB  1 
ATOM   16143 C CG  . GLN E 2 63  ? -45.918 35.309  57.174  1.00 59.26  ? 340  GLN E CG  1 
ATOM   16144 C CD  . GLN E 2 63  ? -46.033 34.063  58.028  1.00 59.30  ? 340  GLN E CD  1 
ATOM   16145 O OE1 . GLN E 2 63  ? -47.058 33.834  58.671  1.00 80.99  ? 340  GLN E OE1 1 
ATOM   16146 N NE2 . GLN E 2 63  ? -44.977 33.258  58.054  1.00 53.29  ? 340  GLN E NE2 1 
ATOM   16147 N N   . LEU E 2 64  ? -49.154 38.548  56.571  1.00 64.34  ? 341  LEU E N   1 
ATOM   16148 C CA  . LEU E 2 64  ? -50.506 39.077  56.412  1.00 67.39  ? 341  LEU E CA  1 
ATOM   16149 C C   . LEU E 2 64  ? -50.610 39.986  55.193  1.00 81.82  ? 341  LEU E C   1 
ATOM   16150 O O   . LEU E 2 64  ? -51.622 39.969  54.482  1.00 87.25  ? 341  LEU E O   1 
ATOM   16151 C CB  . LEU E 2 64  ? -50.932 39.832  57.673  1.00 64.53  ? 341  LEU E CB  1 
ATOM   16152 C CG  . LEU E 2 64  ? -50.877 39.096  59.014  1.00 66.23  ? 341  LEU E CG  1 
ATOM   16153 C CD1 . LEU E 2 64  ? -51.501 39.939  60.110  1.00 59.85  ? 341  LEU E CD1 1 
ATOM   16154 C CD2 . LEU E 2 64  ? -51.555 37.741  58.930  1.00 80.06  ? 341  LEU E CD2 1 
ATOM   16155 N N   . SER E 2 65  ? -49.571 40.784  54.933  1.00 72.11  ? 342  SER E N   1 
ATOM   16156 C CA  . SER E 2 65  ? -49.649 41.810  53.898  1.00 68.67  ? 342  SER E CA  1 
ATOM   16157 C C   . SER E 2 65  ? -49.461 41.228  52.502  1.00 75.98  ? 342  SER E C   1 
ATOM   16158 O O   . SER E 2 65  ? -50.110 41.675  51.550  1.00 91.99  ? 342  SER E O   1 
ATOM   16159 C CB  . SER E 2 65  ? -48.612 42.900  54.167  1.00 60.64  ? 342  SER E CB  1 
ATOM   16160 O OG  . SER E 2 65  ? -47.296 42.403  54.004  1.00 90.27  ? 342  SER E OG  1 
ATOM   16161 N N   . ASP E 2 66  ? -48.581 40.241  52.358  1.00 73.80  ? 343  ASP E N   1 
ATOM   16162 C CA  . ASP E 2 66  ? -48.336 39.593  51.073  1.00 77.11  ? 343  ASP E CA  1 
ATOM   16163 C C   . ASP E 2 66  ? -48.447 38.087  51.256  1.00 85.80  ? 343  ASP E C   1 
ATOM   16164 O O   . ASP E 2 66  ? -47.602 37.473  51.916  1.00 83.40  ? 343  ASP E O   1 
ATOM   16165 C CB  . ASP E 2 66  ? -46.966 39.967  50.510  1.00 82.90  ? 343  ASP E CB  1 
ATOM   16166 C CG  . ASP E 2 66  ? -46.625 39.191  49.254  1.00 90.32  ? 343  ASP E CG  1 
ATOM   16167 O OD1 . ASP E 2 66  ? -47.267 39.435  48.210  1.00 88.57  ? 343  ASP E OD1 1 
ATOM   16168 O OD2 . ASP E 2 66  ? -45.722 38.329  49.312  1.00 108.34 ? 343  ASP E OD2 1 
ATOM   16169 N N   . TYR E 2 67  ? -49.491 37.495  50.678  1.00 87.36  ? 344  TYR E N   1 
ATOM   16170 C CA  . TYR E 2 67  ? -49.628 36.047  50.609  1.00 77.99  ? 344  TYR E CA  1 
ATOM   16171 C C   . TYR E 2 67  ? -49.582 35.555  49.165  1.00 87.39  ? 344  TYR E C   1 
ATOM   16172 O O   . TYR E 2 67  ? -50.183 34.531  48.826  1.00 75.87  ? 344  TYR E O   1 
ATOM   16173 C CB  . TYR E 2 67  ? -50.907 35.581  51.305  1.00 71.62  ? 344  TYR E CB  1 
ATOM   16174 C CG  . TYR E 2 67  ? -52.188 36.262  50.868  1.00 73.72  ? 344  TYR E CG  1 
ATOM   16175 C CD1 . TYR E 2 67  ? -52.580 37.477  51.420  1.00 79.94  ? 344  TYR E CD1 1 
ATOM   16176 C CD2 . TYR E 2 67  ? -53.020 35.674  49.924  1.00 64.88  ? 344  TYR E CD2 1 
ATOM   16177 C CE1 . TYR E 2 67  ? -53.758 38.094  51.033  1.00 73.73  ? 344  TYR E CE1 1 
ATOM   16178 C CE2 . TYR E 2 67  ? -54.197 36.283  49.531  1.00 78.21  ? 344  TYR E CE2 1 
ATOM   16179 C CZ  . TYR E 2 67  ? -54.562 37.492  50.088  1.00 82.56  ? 344  TYR E CZ  1 
ATOM   16180 O OH  . TYR E 2 67  ? -55.734 38.099  49.696  1.00 84.27  ? 344  TYR E OH  1 
ATOM   16181 N N   . SER E 2 68  ? -48.862 36.286  48.308  1.00 92.27  ? 345  SER E N   1 
ATOM   16182 C CA  . SER E 2 68  ? -48.714 35.878  46.916  1.00 72.03  ? 345  SER E CA  1 
ATOM   16183 C C   . SER E 2 68  ? -47.883 34.609  46.791  1.00 66.52  ? 345  SER E C   1 
ATOM   16184 O O   . SER E 2 68  ? -48.115 33.804  45.882  1.00 73.95  ? 345  SER E O   1 
ATOM   16185 C CB  . SER E 2 68  ? -48.080 37.003  46.101  1.00 76.08  ? 345  SER E CB  1 
ATOM   16186 O OG  . SER E 2 68  ? -46.734 37.214  46.494  1.00 95.11  ? 345  SER E OG  1 
ATOM   16187 N N   . ASP E 2 69  ? -46.920 34.408  47.696  1.00 70.82  ? 346  ASP E N   1 
ATOM   16188 C CA  . ASP E 2 69  ? -46.079 33.217  47.650  1.00 71.42  ? 346  ASP E CA  1 
ATOM   16189 C C   . ASP E 2 69  ? -46.860 31.938  47.927  1.00 69.71  ? 346  ASP E C   1 
ATOM   16190 O O   . ASP E 2 69  ? -46.358 30.848  47.632  1.00 70.48  ? 346  ASP E O   1 
ATOM   16191 C CB  . ASP E 2 69  ? -44.923 33.350  48.646  1.00 52.84  ? 346  ASP E CB  1 
ATOM   16192 C CG  . ASP E 2 69  ? -45.361 33.930  49.979  1.00 75.97  ? 346  ASP E CG  1 
ATOM   16193 O OD1 . ASP E 2 69  ? -46.577 33.917  50.264  1.00 100.40 ? 346  ASP E OD1 1 
ATOM   16194 O OD2 . ASP E 2 69  ? -44.487 34.386  50.747  1.00 66.48  ? 346  ASP E OD2 1 
ATOM   16195 N N   . ILE E 2 70  ? -48.066 32.043  48.476  1.00 72.92  ? 347  ILE E N   1 
ATOM   16196 C CA  . ILE E 2 70  ? -48.866 30.885  48.843  1.00 73.05  ? 347  ILE E CA  1 
ATOM   16197 C C   . ILE E 2 70  ? -50.154 30.801  48.020  1.00 71.08  ? 347  ILE E C   1 
ATOM   16198 O O   . ILE E 2 70  ? -51.092 30.105  48.404  1.00 78.34  ? 347  ILE E O   1 
ATOM   16199 C CB  . ILE E 2 70  ? -49.144 30.871  50.356  1.00 66.85  ? 347  ILE E CB  1 
ATOM   16200 C CG1 . ILE E 2 70  ? -50.173 31.935  50.737  1.00 66.03  ? 347  ILE E CG1 1 
ATOM   16201 C CG2 . ILE E 2 70  ? -47.854 31.070  51.139  1.00 57.79  ? 347  ILE E CG2 1 
ATOM   16202 C CD1 . ILE E 2 70  ? -50.374 32.058  52.223  1.00 69.45  ? 347  ILE E CD1 1 
ATOM   16203 N N   . VAL E 2 71  ? -50.205 31.487  46.877  1.00 78.44  ? 348  VAL E N   1 
ATOM   16204 C CA  . VAL E 2 71  ? -51.311 31.361  45.938  1.00 75.65  ? 348  VAL E CA  1 
ATOM   16205 C C   . VAL E 2 71  ? -50.746 31.095  44.550  1.00 75.56  ? 348  VAL E C   1 
ATOM   16206 O O   . VAL E 2 71  ? -49.565 31.321  44.277  1.00 83.44  ? 348  VAL E O   1 
ATOM   16207 C CB  . VAL E 2 71  ? -52.225 32.607  45.913  1.00 73.34  ? 348  VAL E CB  1 
ATOM   16208 C CG1 . VAL E 2 71  ? -52.935 32.777  47.247  1.00 71.44  ? 348  VAL E CG1 1 
ATOM   16209 C CG2 . VAL E 2 71  ? -51.424 33.849  45.553  1.00 86.44  ? 348  VAL E CG2 1 
ATOM   16210 N N   . THR E 2 72  ? -51.614 30.607  43.668  1.00 76.87  ? 349  THR E N   1 
ATOM   16211 C CA  . THR E 2 72  ? -51.229 30.273  42.305  1.00 73.14  ? 349  THR E CA  1 
ATOM   16212 C C   . THR E 2 72  ? -52.403 30.565  41.379  1.00 69.51  ? 349  THR E C   1 
ATOM   16213 O O   . THR E 2 72  ? -53.449 31.065  41.804  1.00 70.28  ? 349  THR E O   1 
ATOM   16214 C CB  . THR E 2 72  ? -50.790 28.810  42.195  1.00 78.63  ? 349  THR E CB  1 
ATOM   16215 O OG1 . THR E 2 72  ? -50.329 28.547  40.864  1.00 107.82 ? 349  THR E OG1 1 
ATOM   16216 C CG2 . THR E 2 72  ? -51.951 27.880  42.515  1.00 83.39  ? 349  THR E CG2 1 
ATOM   16217 N N   . THR E 2 73  ? -52.220 30.250  40.101  1.00 62.11  ? 350  THR E N   1 
ATOM   16218 C CA  . THR E 2 73  ? -53.264 30.430  39.106  1.00 70.98  ? 350  THR E CA  1 
ATOM   16219 C C   . THR E 2 73  ? -54.049 29.135  38.915  1.00 84.32  ? 350  THR E C   1 
ATOM   16220 O O   . THR E 2 73  ? -53.717 28.082  39.464  1.00 84.24  ? 350  THR E O   1 
ATOM   16221 C CB  . THR E 2 73  ? -52.668 30.891  37.774  1.00 76.59  ? 350  THR E CB  1 
ATOM   16222 O OG1 . THR E 2 73  ? -51.829 29.860  37.238  1.00 84.05  ? 350  THR E OG1 1 
ATOM   16223 C CG2 . THR E 2 73  ? -51.849 32.161  37.965  1.00 78.78  ? 350  THR E CG2 1 
ATOM   16224 N N   . LEU E 2 74  ? -55.111 29.228  38.120  1.00 71.98  ? 351  LEU E N   1 
ATOM   16225 C CA  . LEU E 2 74  ? -55.942 28.072  37.813  1.00 61.75  ? 351  LEU E CA  1 
ATOM   16226 C C   . LEU E 2 74  ? -55.255 27.206  36.764  1.00 77.53  ? 351  LEU E C   1 
ATOM   16227 O O   . LEU E 2 74  ? -54.890 27.690  35.688  1.00 90.08  ? 351  LEU E O   1 
ATOM   16228 C CB  . LEU E 2 74  ? -57.314 28.533  37.317  1.00 57.67  ? 351  LEU E CB  1 
ATOM   16229 C CG  . LEU E 2 74  ? -58.564 27.661  37.484  1.00 62.13  ? 351  LEU E CG  1 
ATOM   16230 C CD1 . LEU E 2 74  ? -59.778 28.400  36.943  1.00 57.45  ? 351  LEU E CD1 1 
ATOM   16231 C CD2 . LEU E 2 74  ? -58.429 26.317  36.792  1.00 72.57  ? 351  LEU E CD2 1 
ATOM   16232 N N   . ASP E 2 75  ? -55.076 25.923  37.080  1.00 69.12  ? 352  ASP E N   1 
ATOM   16233 C CA  . ASP E 2 75  ? -54.578 24.952  36.107  1.00 66.52  ? 352  ASP E CA  1 
ATOM   16234 C C   . ASP E 2 75  ? -55.786 24.386  35.376  1.00 71.22  ? 352  ASP E C   1 
ATOM   16235 O O   . ASP E 2 75  ? -56.424 23.430  35.822  1.00 70.98  ? 352  ASP E O   1 
ATOM   16236 C CB  . ASP E 2 75  ? -53.761 23.859  36.782  1.00 70.69  ? 352  ASP E CB  1 
ATOM   16237 C CG  . ASP E 2 75  ? -52.972 23.030  35.787  1.00 86.10  ? 352  ASP E CG  1 
ATOM   16238 O OD1 . ASP E 2 75  ? -52.216 23.622  34.986  1.00 100.72 ? 352  ASP E OD1 1 
ATOM   16239 O OD2 . ASP E 2 75  ? -53.112 21.789  35.801  1.00 80.39  ? 352  ASP E OD2 1 
ATOM   16240 N N   . LEU E 2 76  ? -56.099 24.987  34.233  1.00 63.63  ? 353  LEU E N   1 
ATOM   16241 C CA  . LEU E 2 76  ? -57.329 24.664  33.525  1.00 65.39  ? 353  LEU E CA  1 
ATOM   16242 C C   . LEU E 2 76  ? -57.275 23.261  32.933  1.00 64.34  ? 353  LEU E C   1 
ATOM   16243 O O   . LEU E 2 76  ? -56.253 22.833  32.389  1.00 67.97  ? 353  LEU E O   1 
ATOM   16244 C CB  . LEU E 2 76  ? -57.579 25.690  32.420  1.00 59.28  ? 353  LEU E CB  1 
ATOM   16245 C CG  . LEU E 2 76  ? -59.033 25.917  32.002  1.00 71.46  ? 353  LEU E CG  1 
ATOM   16246 C CD1 . LEU E 2 76  ? -59.731 26.849  32.981  1.00 59.29  ? 353  LEU E CD1 1 
ATOM   16247 C CD2 . LEU E 2 76  ? -59.108 26.466  30.584  1.00 86.09  ? 353  LEU E CD2 1 
ATOM   16248 N N   . ALA E 2 77  ? -58.389 22.543  33.054  1.00 62.14  ? 354  ALA E N   1 
ATOM   16249 C CA  . ALA E 2 77  ? -58.574 21.289  32.349  1.00 62.31  ? 354  ALA E CA  1 
ATOM   16250 C C   . ALA E 2 77  ? -58.691 21.556  30.847  1.00 68.92  ? 354  ALA E C   1 
ATOM   16251 O O   . ALA E 2 77  ? -58.881 22.701  30.431  1.00 68.53  ? 354  ALA E O   1 
ATOM   16252 C CB  . ALA E 2 77  ? -59.820 20.577  32.877  1.00 71.13  ? 354  ALA E CB  1 
ATOM   16253 N N   . PRO E 2 78  ? -58.555 20.521  30.014  1.00 76.28  ? 355  PRO E N   1 
ATOM   16254 C CA  . PRO E 2 78  ? -58.619 20.714  28.554  1.00 66.75  ? 355  PRO E CA  1 
ATOM   16255 C C   . PRO E 2 78  ? -59.849 21.500  28.137  1.00 73.77  ? 355  PRO E C   1 
ATOM   16256 O O   . PRO E 2 78  ? -60.989 21.068  28.370  1.00 78.62  ? 355  PRO E O   1 
ATOM   16257 C CB  . PRO E 2 78  ? -58.672 19.277  28.021  1.00 72.70  ? 355  PRO E CB  1 
ATOM   16258 C CG  . PRO E 2 78  ? -57.853 18.526  28.995  1.00 73.41  ? 355  PRO E CG  1 
ATOM   16259 C CD  . PRO E 2 78  ? -58.125 19.149  30.349  1.00 78.57  ? 355  PRO E CD  1 
ATOM   16260 N N   . PRO E 2 79  ? -59.656 22.667  27.514  1.00 76.45  ? 356  PRO E N   1 
ATOM   16261 C CA  . PRO E 2 79  ? -60.804 23.503  27.138  1.00 76.56  ? 356  PRO E CA  1 
ATOM   16262 C C   . PRO E 2 79  ? -61.511 23.020  25.880  1.00 76.48  ? 356  PRO E C   1 
ATOM   16263 O O   . PRO E 2 79  ? -62.741 23.102  25.792  1.00 74.27  ? 356  PRO E O   1 
ATOM   16264 C CB  . PRO E 2 79  ? -60.168 24.884  26.936  1.00 73.65  ? 356  PRO E CB  1 
ATOM   16265 C CG  . PRO E 2 79  ? -58.776 24.565  26.490  1.00 70.23  ? 356  PRO E CG  1 
ATOM   16266 C CD  . PRO E 2 79  ? -58.376 23.368  27.308  1.00 60.98  ? 356  PRO E CD  1 
ATOM   16267 N N   . THR E 2 80  ? -60.761 22.515  24.906  1.00 84.26  ? 357  THR E N   1 
ATOM   16268 C CA  . THR E 2 80  ? -61.338 22.048  23.654  1.00 78.72  ? 357  THR E CA  1 
ATOM   16269 C C   . THR E 2 80  ? -61.397 20.526  23.629  1.00 71.07  ? 357  THR E C   1 
ATOM   16270 O O   . THR E 2 80  ? -60.620 19.842  24.302  1.00 71.34  ? 357  THR E O   1 
ATOM   16271 C CB  . THR E 2 80  ? -60.534 22.552  22.453  1.00 87.83  ? 357  THR E CB  1 
ATOM   16272 O OG1 . THR E 2 80  ? -59.380 21.724  22.267  1.00 75.80  ? 357  THR E OG1 1 
ATOM   16273 C CG2 . THR E 2 80  ? -60.085 23.988  22.681  1.00 88.98  ? 357  THR E CG2 1 
ATOM   16274 N N   . LYS E 2 81  ? -62.340 20.002  22.843  1.00 72.90  ? 358  LYS E N   1 
ATOM   16275 C CA  . LYS E 2 81  ? -62.468 18.555  22.706  1.00 73.35  ? 358  LYS E CA  1 
ATOM   16276 C C   . LYS E 2 81  ? -61.212 17.951  22.087  1.00 89.87  ? 358  LYS E C   1 
ATOM   16277 O O   . LYS E 2 81  ? -60.799 16.844  22.456  1.00 94.22  ? 358  LYS E O   1 
ATOM   16278 C CB  . LYS E 2 81  ? -63.704 18.217  21.870  1.00 64.08  ? 358  LYS E CB  1 
ATOM   16279 C CG  . LYS E 2 81  ? -64.952 19.015  22.233  1.00 72.95  ? 358  LYS E CG  1 
ATOM   16280 C CD  . LYS E 2 81  ? -66.122 18.668  21.318  1.00 93.49  ? 358  LYS E CD  1 
ATOM   16281 C CE  . LYS E 2 81  ? -66.786 17.357  21.714  1.00 96.42  ? 358  LYS E CE  1 
ATOM   16282 N NZ  . LYS E 2 81  ? -67.401 17.437  23.067  1.00 89.54  ? 358  LYS E NZ  1 
ATOM   16283 N N   . LYS E 2 82  ? -60.584 18.672  21.152  1.00 97.31  ? 359  LYS E N   1 
ATOM   16284 C CA  . LYS E 2 82  ? -59.345 18.190  20.547  1.00 89.46  ? 359  LYS E CA  1 
ATOM   16285 C C   . LYS E 2 82  ? -58.221 18.108  21.572  1.00 80.20  ? 359  LYS E C   1 
ATOM   16286 O O   . LYS E 2 82  ? -57.435 17.155  21.560  1.00 88.71  ? 359  LYS E O   1 
ATOM   16287 C CB  . LYS E 2 82  ? -58.934 19.092  19.381  1.00 93.64  ? 359  LYS E CB  1 
ATOM   16288 C CG  . LYS E 2 82  ? -59.896 19.097  18.201  1.00 115.16 ? 359  LYS E CG  1 
ATOM   16289 C CD  . LYS E 2 82  ? -60.129 17.691  17.669  1.00 130.88 ? 359  LYS E CD  1 
ATOM   16290 C CE  . LYS E 2 82  ? -61.321 17.649  16.722  1.00 142.47 ? 359  LYS E CE  1 
ATOM   16291 N NZ  . LYS E 2 82  ? -62.625 17.605  17.441  1.00 145.03 ? 359  LYS E NZ  1 
ATOM   16292 N N   . LEU E 2 83  ? -58.121 19.099  22.463  1.00 86.75  ? 360  LEU E N   1 
ATOM   16293 C CA  . LEU E 2 83  ? -57.071 19.074  23.481  1.00 80.91  ? 360  LEU E CA  1 
ATOM   16294 C C   . LEU E 2 83  ? -57.276 17.925  24.461  1.00 81.10  ? 360  LEU E C   1 
ATOM   16295 O O   . LEU E 2 83  ? -56.309 17.298  24.902  1.00 89.03  ? 360  LEU E O   1 
ATOM   16296 C CB  . LEU E 2 83  ? -57.021 20.411  24.220  1.00 65.09  ? 360  LEU E CB  1 
ATOM   16297 C CG  . LEU E 2 83  ? -56.419 21.604  23.475  1.00 78.23  ? 360  LEU E CG  1 
ATOM   16298 C CD1 . LEU E 2 83  ? -56.120 22.735  24.443  1.00 73.34  ? 360  LEU E CD1 1 
ATOM   16299 C CD2 . LEU E 2 83  ? -55.157 21.192  22.730  1.00 90.16  ? 360  LEU E CD2 1 
ATOM   16300 N N   . MET E 2 84  ? -58.530 17.639  24.812  1.00 79.82  ? 361  MET E N   1 
ATOM   16301 C CA  . MET E 2 84  ? -58.846 16.490  25.657  1.00 78.68  ? 361  MET E CA  1 
ATOM   16302 C C   . MET E 2 84  ? -58.463 15.183  24.966  1.00 83.12  ? 361  MET E C   1 
ATOM   16303 O O   . MET E 2 84  ? -57.804 14.306  25.557  1.00 82.82  ? 361  MET E O   1 
ATOM   16304 C CB  . MET E 2 84  ? -60.340 16.541  25.992  1.00 71.09  ? 361  MET E CB  1 
ATOM   16305 C CG  . MET E 2 84  ? -60.983 15.284  26.524  1.00 89.95  ? 361  MET E CG  1 
ATOM   16306 S SD  . MET E 2 84  ? -62.512 15.713  27.383  1.00 82.93  ? 361  MET E SD  1 
ATOM   16307 C CE  . MET E 2 84  ? -63.647 15.875  26.004  1.00 74.75  ? 361  MET E CE  1 
ATOM   16308 N N   . MET E 2 85  ? -58.863 15.044  23.699  1.00 83.86  ? 362  MET E N   1 
ATOM   16309 C CA  . MET E 2 85  ? -58.476 13.872  22.927  1.00 92.77  ? 362  MET E CA  1 
ATOM   16310 C C   . MET E 2 85  ? -56.964 13.719  22.889  1.00 89.94  ? 362  MET E C   1 
ATOM   16311 O O   . MET E 2 85  ? -56.453 12.607  23.003  1.00 91.97  ? 362  MET E O   1 
ATOM   16312 C CB  . MET E 2 85  ? -59.026 13.961  21.506  1.00 104.92 ? 362  MET E CB  1 
ATOM   16313 C CG  . MET E 2 85  ? -58.149 13.253  20.484  1.00 111.56 ? 362  MET E CG  1 
ATOM   16314 S SD  . MET E 2 85  ? -58.409 13.765  18.779  1.00 151.97 ? 362  MET E SD  1 
ATOM   16315 C CE  . MET E 2 85  ? -57.289 15.161  18.691  1.00 123.05 ? 362  MET E CE  1 
ATOM   16316 N N   . TRP E 2 86  ? -56.232 14.826  22.730  1.00 91.86  ? 363  TRP E N   1 
ATOM   16317 C CA  . TRP E 2 86  ? -54.773 14.754  22.707  1.00 82.61  ? 363  TRP E CA  1 
ATOM   16318 C C   . TRP E 2 86  ? -54.212 14.374  24.069  1.00 84.23  ? 363  TRP E C   1 
ATOM   16319 O O   . TRP E 2 86  ? -53.209 13.658  24.151  1.00 90.21  ? 363  TRP E O   1 
ATOM   16320 C CB  . TRP E 2 86  ? -54.171 16.082  22.248  1.00 84.03  ? 363  TRP E CB  1 
ATOM   16321 C CG  . TRP E 2 86  ? -54.053 16.226  20.762  1.00 90.62  ? 363  TRP E CG  1 
ATOM   16322 C CD1 . TRP E 2 86  ? -53.516 15.323  19.890  1.00 93.75  ? 363  TRP E CD1 1 
ATOM   16323 C CD2 . TRP E 2 86  ? -54.452 17.354  19.974  1.00 97.18  ? 363  TRP E CD2 1 
ATOM   16324 N NE1 . TRP E 2 86  ? -53.571 15.812  18.608  1.00 88.07  ? 363  TRP E NE1 1 
ATOM   16325 C CE2 . TRP E 2 86  ? -54.142 17.057  18.632  1.00 96.63  ? 363  TRP E CE2 1 
ATOM   16326 C CE3 . TRP E 2 86  ? -55.049 18.582  20.272  1.00 97.51  ? 363  TRP E CE3 1 
ATOM   16327 C CZ2 . TRP E 2 86  ? -54.407 17.943  17.592  1.00 103.88 ? 363  TRP E CZ2 1 
ATOM   16328 C CZ3 . TRP E 2 86  ? -55.314 19.459  19.238  1.00 100.95 ? 363  TRP E CZ3 1 
ATOM   16329 C CH2 . TRP E 2 86  ? -54.993 19.136  17.914  1.00 101.09 ? 363  TRP E CH2 1 
ATOM   16330 N N   . LYS E 2 87  ? -54.826 14.867  25.147  1.00 91.08  ? 364  LYS E N   1 
ATOM   16331 C CA  . LYS E 2 87  ? -54.438 14.432  26.483  1.00 89.35  ? 364  LYS E CA  1 
ATOM   16332 C C   . LYS E 2 87  ? -54.522 12.921  26.616  1.00 83.02  ? 364  LYS E C   1 
ATOM   16333 O O   . LYS E 2 87  ? -53.702 12.311  27.312  1.00 87.25  ? 364  LYS E O   1 
ATOM   16334 C CB  . LYS E 2 87  ? -55.321 15.103  27.537  1.00 84.69  ? 364  LYS E CB  1 
ATOM   16335 C CG  . LYS E 2 87  ? -54.712 15.127  28.928  1.00 94.44  ? 364  LYS E CG  1 
ATOM   16336 C CD  . LYS E 2 87  ? -55.415 16.130  29.825  1.00 99.58  ? 364  LYS E CD  1 
ATOM   16337 C CE  . LYS E 2 87  ? -54.945 16.009  31.265  1.00 94.06  ? 364  LYS E CE  1 
ATOM   16338 N NZ  . LYS E 2 87  ? -55.807 16.782  32.202  1.00 105.24 ? 364  LYS E NZ  1 
ATOM   16339 N N   . GLU E 2 88  ? -55.501 12.300  25.963  1.00 83.78  ? 365  GLU E N   1 
ATOM   16340 C CA  . GLU E 2 88  ? -55.548 10.840  26.050  1.00 83.52  ? 365  GLU E CA  1 
ATOM   16341 C C   . GLU E 2 88  ? -54.668 10.148  25.002  1.00 92.98  ? 365  GLU E C   1 
ATOM   16342 O O   . GLU E 2 88  ? -53.852 9.287   25.344  1.00 90.09  ? 365  GLU E O   1 
ATOM   16343 C CB  . GLU E 2 88  ? -56.992 10.343  25.944  1.00 88.91  ? 365  GLU E CB  1 
ATOM   16344 C CG  . GLU E 2 88  ? -57.118 8.837   26.104  1.00 101.38 ? 365  GLU E CG  1 
ATOM   16345 C CD  . GLU E 2 88  ? -58.535 8.350   25.898  1.00 119.14 ? 365  GLU E CD  1 
ATOM   16346 O OE1 . GLU E 2 88  ? -59.448 9.201   25.860  1.00 105.35 ? 365  GLU E OE1 1 
ATOM   16347 O OE2 . GLU E 2 88  ? -58.735 7.122   25.776  1.00 124.46 ? 365  GLU E OE2 1 
ATOM   16348 N N   . THR E 2 89  ? -54.822 10.516  23.728  1.00 92.13  ? 366  THR E N   1 
ATOM   16349 C CA  . THR E 2 89  ? -54.119 9.849   22.635  1.00 74.40  ? 366  THR E CA  1 
ATOM   16350 C C   . THR E 2 89  ? -52.648 10.240  22.591  1.00 78.45  ? 366  THR E C   1 
ATOM   16351 O O   . THR E 2 89  ? -51.785 9.398   22.318  1.00 83.11  ? 366  THR E O   1 
ATOM   16352 C CB  . THR E 2 89  ? -54.783 10.188  21.299  1.00 93.41  ? 366  THR E CB  1 
ATOM   16353 O OG1 . THR E 2 89  ? -54.779 11.609  21.109  1.00 101.96 ? 366  THR E OG1 1 
ATOM   16354 C CG2 . THR E 2 89  ? -56.218 9.687   21.271  1.00 78.69  ? 366  THR E CG2 1 
ATOM   16355 N N   . GLY E 2 90  ? -52.345 11.516  22.815  1.00 80.82  ? 367  GLY E N   1 
ATOM   16356 C CA  . GLY E 2 90  ? -50.963 11.936  22.901  1.00 79.58  ? 367  GLY E CA  1 
ATOM   16357 C C   . GLY E 2 90  ? -50.270 11.356  24.118  1.00 81.35  ? 367  GLY E C   1 
ATOM   16358 O O   . GLY E 2 90  ? -50.899 10.897  25.074  1.00 108.04 ? 367  GLY E O   1 
ATOM   16359 N N   . GLY E 2 91  ? -48.943 11.380  24.077  1.00 57.58  ? 368  GLY E N   1 
ATOM   16360 C CA  . GLY E 2 91  ? -48.156 10.762  25.123  1.00 85.00  ? 368  GLY E CA  1 
ATOM   16361 C C   . GLY E 2 91  ? -47.557 9.450   24.672  1.00 86.85  ? 368  GLY E C   1 
ATOM   16362 O O   . GLY E 2 91  ? -48.198 8.704   23.927  1.00 83.69  ? 368  GLY E O   1 
ATOM   16363 N N   . VAL E 2 92  ? -46.337 9.154   25.130  1.00 75.81  ? 369  VAL E N   1 
ATOM   16364 C CA  . VAL E 2 92  ? -45.579 8.032   24.583  1.00 77.78  ? 369  VAL E CA  1 
ATOM   16365 C C   . VAL E 2 92  ? -46.345 6.722   24.744  1.00 82.43  ? 369  VAL E C   1 
ATOM   16366 O O   . VAL E 2 92  ? -46.347 5.878   23.838  1.00 87.77  ? 369  VAL E O   1 
ATOM   16367 C CB  . VAL E 2 92  ? -44.185 7.977   25.234  1.00 72.54  ? 369  VAL E CB  1 
ATOM   16368 C CG1 . VAL E 2 92  ? -43.379 9.200   24.836  1.00 82.21  ? 369  VAL E CG1 1 
ATOM   16369 C CG2 . VAL E 2 92  ? -44.303 7.904   26.747  1.00 83.23  ? 369  VAL E CG2 1 
ATOM   16370 N N   . GLU E 2 93  ? -47.044 6.557   25.874  1.00 88.41  ? 370  GLU E N   1 
ATOM   16371 C CA  . GLU E 2 93  ? -47.710 5.292   26.180  1.00 80.74  ? 370  GLU E CA  1 
ATOM   16372 C C   . GLU E 2 93  ? -48.731 4.920   25.112  1.00 81.20  ? 370  GLU E C   1 
ATOM   16373 O O   . GLU E 2 93  ? -48.924 3.735   24.813  1.00 86.83  ? 370  GLU E O   1 
ATOM   16374 C CB  . GLU E 2 93  ? -48.373 5.371   27.559  1.00 78.90  ? 370  GLU E CB  1 
ATOM   16375 C CG  . GLU E 2 93  ? -49.674 6.181   27.630  1.00 102.31 ? 370  GLU E CG  1 
ATOM   16376 C CD  . GLU E 2 93  ? -49.486 7.654   27.304  1.00 114.30 ? 370  GLU E CD  1 
ATOM   16377 O OE1 . GLU E 2 93  ? -48.693 8.320   28.001  1.00 103.97 ? 370  GLU E OE1 1 
ATOM   16378 O OE2 . GLU E 2 93  ? -50.138 8.146   26.357  1.00 123.38 ? 370  GLU E OE2 1 
ATOM   16379 N N   . LYS E 2 94  ? -49.395 5.914   24.526  1.00 74.38  ? 371  LYS E N   1 
ATOM   16380 C CA  . LYS E 2 94  ? -50.339 5.682   23.442  1.00 70.79  ? 371  LYS E CA  1 
ATOM   16381 C C   . LYS E 2 94  ? -49.726 5.940   22.075  1.00 82.63  ? 371  LYS E C   1 
ATOM   16382 O O   . LYS E 2 94  ? -50.006 5.199   21.129  1.00 82.36  ? 371  LYS E O   1 
ATOM   16383 C CB  . LYS E 2 94  ? -51.578 6.565   23.615  1.00 76.68  ? 371  LYS E CB  1 
ATOM   16384 C CG  . LYS E 2 94  ? -52.591 6.056   24.624  1.00 80.10  ? 371  LYS E CG  1 
ATOM   16385 C CD  . LYS E 2 94  ? -53.247 4.771   24.153  1.00 73.54  ? 371  LYS E CD  1 
ATOM   16386 C CE  . LYS E 2 94  ? -54.487 4.459   24.974  1.00 79.92  ? 371  LYS E CE  1 
ATOM   16387 N NZ  . LYS E 2 94  ? -54.148 4.013   26.353  1.00 113.09 ? 371  LYS E NZ  1 
ATOM   16388 N N   . LEU E 2 95  ? -48.887 6.974   21.959  1.00 77.26  ? 372  LEU E N   1 
ATOM   16389 C CA  . LEU E 2 95  ? -48.279 7.306   20.674  1.00 66.13  ? 372  LEU E CA  1 
ATOM   16390 C C   . LEU E 2 95  ? -47.500 6.128   20.106  1.00 67.99  ? 372  LEU E C   1 
ATOM   16391 O O   . LEU E 2 95  ? -47.636 5.796   18.924  1.00 77.22  ? 372  LEU E O   1 
ATOM   16392 C CB  . LEU E 2 95  ? -47.375 8.532   20.816  1.00 65.88  ? 372  LEU E CB  1 
ATOM   16393 C CG  . LEU E 2 95  ? -48.042 9.909   20.796  1.00 71.22  ? 372  LEU E CG  1 
ATOM   16394 C CD1 . LEU E 2 95  ? -46.988 10.995  20.682  1.00 68.47  ? 372  LEU E CD1 1 
ATOM   16395 C CD2 . LEU E 2 95  ? -49.035 10.007  19.647  1.00 68.02  ? 372  LEU E CD2 1 
ATOM   16396 N N   . PHE E 2 96  ? -46.682 5.473   20.930  1.00 68.70  ? 373  PHE E N   1 
ATOM   16397 C CA  . PHE E 2 96  ? -45.886 4.368   20.409  1.00 70.41  ? 373  PHE E CA  1 
ATOM   16398 C C   . PHE E 2 96  ? -46.695 3.094   20.211  1.00 80.63  ? 373  PHE E C   1 
ATOM   16399 O O   . PHE E 2 96  ? -46.150 2.109   19.702  1.00 85.90  ? 373  PHE E O   1 
ATOM   16400 C CB  . PHE E 2 96  ? -44.692 4.096   21.325  1.00 72.13  ? 373  PHE E CB  1 
ATOM   16401 C CG  . PHE E 2 96  ? -43.573 5.080   21.157  1.00 58.35  ? 373  PHE E CG  1 
ATOM   16402 C CD1 . PHE E 2 96  ? -43.619 6.313   21.783  1.00 68.29  ? 373  PHE E CD1 1 
ATOM   16403 C CD2 . PHE E 2 96  ? -42.483 4.779   20.357  1.00 64.50  ? 373  PHE E CD2 1 
ATOM   16404 C CE1 . PHE E 2 96  ? -42.593 7.226   21.624  1.00 76.32  ? 373  PHE E CE1 1 
ATOM   16405 C CE2 . PHE E 2 96  ? -41.454 5.688   20.192  1.00 71.26  ? 373  PHE E CE2 1 
ATOM   16406 C CZ  . PHE E 2 96  ? -41.509 6.911   20.827  1.00 74.03  ? 373  PHE E CZ  1 
ATOM   16407 N N   . PHE E 2 97  ? -47.973 3.091   20.587  1.00 71.56  ? 374  PHE E N   1 
ATOM   16408 C CA  . PHE E 2 97  ? -48.821 1.919   20.443  1.00 68.38  ? 374  PHE E CA  1 
ATOM   16409 C C   . PHE E 2 97  ? -50.013 2.160   19.526  1.00 71.08  ? 374  PHE E C   1 
ATOM   16410 O O   . PHE E 2 97  ? -50.844 1.258   19.364  1.00 79.06  ? 374  PHE E O   1 
ATOM   16411 C CB  . PHE E 2 97  ? -49.320 1.445   21.818  1.00 78.25  ? 374  PHE E CB  1 
ATOM   16412 C CG  . PHE E 2 97  ? -48.233 0.904   22.715  1.00 93.25  ? 374  PHE E CG  1 
ATOM   16413 C CD1 . PHE E 2 97  ? -47.195 1.715   23.150  1.00 79.53  ? 374  PHE E CD1 1 
ATOM   16414 C CD2 . PHE E 2 97  ? -48.256 -0.418  23.124  1.00 107.10 ? 374  PHE E CD2 1 
ATOM   16415 C CE1 . PHE E 2 97  ? -46.203 1.217   23.973  1.00 84.13  ? 374  PHE E CE1 1 
ATOM   16416 C CE2 . PHE E 2 97  ? -47.266 -0.922  23.948  1.00 108.63 ? 374  PHE E CE2 1 
ATOM   16417 C CZ  . PHE E 2 97  ? -46.238 -0.103  24.373  1.00 102.53 ? 374  PHE E CZ  1 
ATOM   16418 N N   . LEU E 2 98  ? -50.119 3.339   18.921  1.00 74.21  ? 375  LEU E N   1 
ATOM   16419 C CA  . LEU E 2 98  ? -51.248 3.720   18.088  1.00 67.07  ? 375  LEU E CA  1 
ATOM   16420 C C   . LEU E 2 98  ? -50.761 4.180   16.722  1.00 68.99  ? 375  LEU E C   1 
ATOM   16421 O O   . LEU E 2 98  ? -49.657 4.721   16.601  1.00 72.12  ? 375  LEU E O   1 
ATOM   16422 C CB  . LEU E 2 98  ? -52.062 4.844   18.747  1.00 64.81  ? 375  LEU E CB  1 
ATOM   16423 C CG  . LEU E 2 98  ? -52.977 4.430   19.900  1.00 59.07  ? 375  LEU E CG  1 
ATOM   16424 C CD1 . LEU E 2 98  ? -53.854 5.593   20.341  1.00 76.73  ? 375  LEU E CD1 1 
ATOM   16425 C CD2 . LEU E 2 98  ? -53.826 3.234   19.500  1.00 46.55  ? 375  LEU E CD2 1 
ATOM   16426 N N   . PRO E 2 99  ? -51.565 3.985   15.679  1.00 71.74  ? 376  PRO E N   1 
ATOM   16427 C CA  . PRO E 2 99  ? -51.127 4.369   14.334  1.00 74.28  ? 376  PRO E CA  1 
ATOM   16428 C C   . PRO E 2 99  ? -51.118 5.877   14.153  1.00 68.99  ? 376  PRO E C   1 
ATOM   16429 O O   . PRO E 2 99  ? -51.850 6.614   14.818  1.00 62.78  ? 376  PRO E O   1 
ATOM   16430 C CB  . PRO E 2 99  ? -52.168 3.707   13.426  1.00 71.01  ? 376  PRO E CB  1 
ATOM   16431 C CG  . PRO E 2 99  ? -53.403 3.697   14.262  1.00 74.18  ? 376  PRO E CG  1 
ATOM   16432 C CD  . PRO E 2 99  ? -52.923 3.413   15.666  1.00 76.71  ? 376  PRO E CD  1 
ATOM   16433 N N   . ALA E 2 100 ? -50.265 6.333   13.234  1.00 64.92  ? 377  ALA E N   1 
ATOM   16434 C CA  . ALA E 2 100 ? -50.224 7.755   12.917  1.00 66.46  ? 377  ALA E CA  1 
ATOM   16435 C C   . ALA E 2 100 ? -51.502 8.193   12.214  1.00 75.07  ? 377  ALA E C   1 
ATOM   16436 O O   . ALA E 2 100 ? -52.044 9.265   12.508  1.00 77.44  ? 377  ALA E O   1 
ATOM   16437 C CB  . ALA E 2 100 ? -48.995 8.064   12.063  1.00 71.00  ? 377  ALA E CB  1 
ATOM   16438 N N   . GLN E 2 101 ? -51.997 7.377   11.282  1.00 74.13  ? 378  GLN E N   1 
ATOM   16439 C CA  . GLN E 2 101 ? -53.295 7.612   10.667  1.00 62.26  ? 378  GLN E CA  1 
ATOM   16440 C C   . GLN E 2 101 ? -54.335 6.830   11.452  1.00 68.64  ? 378  GLN E C   1 
ATOM   16441 O O   . GLN E 2 101 ? -54.299 5.590   11.438  1.00 73.27  ? 378  GLN E O   1 
ATOM   16442 C CB  . GLN E 2 101 ? -53.290 7.178   9.208   1.00 70.34  ? 378  GLN E CB  1 
ATOM   16443 C CG  . GLN E 2 101 ? -54.553 7.545   8.440   1.00 73.66  ? 378  GLN E CG  1 
ATOM   16444 C CD  . GLN E 2 101 ? -54.950 8.998   8.623   1.00 75.45  ? 378  GLN E CD  1 
ATOM   16445 O OE1 . GLN E 2 101 ? -54.132 9.903   8.454   1.00 58.79  ? 378  GLN E OE1 1 
ATOM   16446 N NE2 . GLN E 2 101 ? -56.216 9.229   8.958   1.00 81.52  ? 378  GLN E NE2 1 
ATOM   16447 N N   . PRO E 2 102 ? -55.258 7.489   12.151  1.00 68.85  ? 379  PRO E N   1 
ATOM   16448 C CA  . PRO E 2 102 ? -56.194 6.754   13.013  1.00 62.75  ? 379  PRO E CA  1 
ATOM   16449 C C   . PRO E 2 102 ? -57.034 5.767   12.215  1.00 68.08  ? 379  PRO E C   1 
ATOM   16450 O O   . PRO E 2 102 ? -57.581 6.096   11.159  1.00 61.61  ? 379  PRO E O   1 
ATOM   16451 C CB  . PRO E 2 102 ? -57.053 7.862   13.634  1.00 51.51  ? 379  PRO E CB  1 
ATOM   16452 C CG  . PRO E 2 102 ? -56.230 9.104   13.526  1.00 59.44  ? 379  PRO E CG  1 
ATOM   16453 C CD  . PRO E 2 102 ? -55.380 8.950   12.301  1.00 62.89  ? 379  PRO E CD  1 
ATOM   16454 N N   . LEU E 2 103 ? -57.114 4.541   12.726  1.00 65.63  ? 380  LEU E N   1 
ATOM   16455 C CA  . LEU E 2 103 ? -57.892 3.467   12.125  1.00 76.40  ? 380  LEU E CA  1 
ATOM   16456 C C   . LEU E 2 103 ? -59.108 3.214   13.007  1.00 89.52  ? 380  LEU E C   1 
ATOM   16457 O O   . LEU E 2 103 ? -58.964 2.805   14.165  1.00 102.55 ? 380  LEU E O   1 
ATOM   16458 C CB  . LEU E 2 103 ? -57.049 2.201   11.976  1.00 69.89  ? 380  LEU E CB  1 
ATOM   16459 C CG  . LEU E 2 103 ? -55.784 2.375   11.132  1.00 72.63  ? 380  LEU E CG  1 
ATOM   16460 C CD1 . LEU E 2 103 ? -54.996 1.077   11.043  1.00 94.07  ? 380  LEU E CD1 1 
ATOM   16461 C CD2 . LEU E 2 103 ? -56.131 2.895   9.746   1.00 79.44  ? 380  LEU E CD2 1 
ATOM   16462 N N   . TRP E 2 104 ? -60.299 3.453   12.457  1.00 77.49  ? 381  TRP E N   1 
ATOM   16463 C CA  . TRP E 2 104 ? -61.508 3.492   13.272  1.00 78.67  ? 381  TRP E CA  1 
ATOM   16464 C C   . TRP E 2 104 ? -62.048 2.103   13.589  1.00 80.11  ? 381  TRP E C   1 
ATOM   16465 O O   . TRP E 2 104 ? -62.655 1.910   14.649  1.00 90.51  ? 381  TRP E O   1 
ATOM   16466 C CB  . TRP E 2 104 ? -62.572 4.330   12.564  1.00 79.16  ? 381  TRP E CB  1 
ATOM   16467 C CG  . TRP E 2 104 ? -62.152 5.756   12.388  1.00 81.28  ? 381  TRP E CG  1 
ATOM   16468 C CD1 . TRP E 2 104 ? -61.190 6.419   13.096  1.00 77.48  ? 381  TRP E CD1 1 
ATOM   16469 C CD2 . TRP E 2 104 ? -62.658 6.692   11.429  1.00 79.55  ? 381  TRP E CD2 1 
ATOM   16470 N NE1 . TRP E 2 104 ? -61.075 7.711   12.644  1.00 73.99  ? 381  TRP E NE1 1 
ATOM   16471 C CE2 . TRP E 2 104 ? -61.964 7.903   11.620  1.00 79.37  ? 381  TRP E CE2 1 
ATOM   16472 C CE3 . TRP E 2 104 ? -63.633 6.624   10.429  1.00 79.65  ? 381  TRP E CE3 1 
ATOM   16473 C CZ2 . TRP E 2 104 ? -62.213 9.036   10.848  1.00 88.04  ? 381  TRP E CZ2 1 
ATOM   16474 C CZ3 . TRP E 2 104 ? -63.881 7.751   9.666   1.00 77.73  ? 381  TRP E CZ3 1 
ATOM   16475 C CH2 . TRP E 2 104 ? -63.174 8.940   9.880   1.00 76.48  ? 381  TRP E CH2 1 
ATOM   16476 N N   . ASN E 2 105 ? -61.851 1.134   12.701  1.00 81.17  ? 382  ASN E N   1 
ATOM   16477 C CA  . ASN E 2 105 ? -62.255 -0.242  12.957  1.00 81.95  ? 382  ASN E CA  1 
ATOM   16478 C C   . ASN E 2 105 ? -61.094 -1.008  13.578  1.00 83.78  ? 382  ASN E C   1 
ATOM   16479 O O   . ASN E 2 105 ? -59.946 -0.874  13.144  1.00 84.42  ? 382  ASN E O   1 
ATOM   16480 C CB  . ASN E 2 105 ? -62.704 -0.926  11.665  1.00 87.35  ? 382  ASN E CB  1 
ATOM   16481 C CG  . ASN E 2 105 ? -63.614 -2.114  11.918  1.00 83.46  ? 382  ASN E CG  1 
ATOM   16482 O OD1 . ASN E 2 105 ? -63.197 -3.119  12.493  1.00 94.55  ? 382  ASN E OD1 1 
ATOM   16483 N ND2 . ASN E 2 105 ? -64.859 -2.012  11.467  1.00 74.76  ? 382  ASN E ND2 1 
ATOM   16484 N N   . ASN E 2 106 ? -61.398 -1.821  14.595  1.00 81.91  ? 383  ASN E N   1 
ATOM   16485 C CA  . ASN E 2 106 ? -60.349 -2.506  15.346  1.00 84.95  ? 383  ASN E CA  1 
ATOM   16486 C C   . ASN E 2 106 ? -59.650 -3.606  14.559  1.00 96.49  ? 383  ASN E C   1 
ATOM   16487 O O   . ASN E 2 106 ? -58.626 -4.109  15.025  1.00 106.07 ? 383  ASN E O   1 
ATOM   16488 C CB  . ASN E 2 106 ? -60.911 -3.093  16.641  1.00 81.58  ? 383  ASN E CB  1 
ATOM   16489 C CG  . ASN E 2 106 ? -61.184 -2.036  17.687  1.00 100.94 ? 383  ASN E CG  1 
ATOM   16490 O OD1 . ASN E 2 106 ? -61.944 -1.096  17.458  1.00 118.49 ? 383  ASN E OD1 1 
ATOM   16491 N ND2 . ASN E 2 106 ? -60.549 -2.180  18.844  1.00 69.89  ? 383  ASN E ND2 1 
ATOM   16492 N N   . ARG E 2 107 ? -60.160 -3.987  13.390  1.00 85.14  ? 384  ARG E N   1 
ATOM   16493 C CA  . ARG E 2 107 ? -59.471 -4.977  12.568  1.00 82.12  ? 384  ARG E CA  1 
ATOM   16494 C C   . ARG E 2 107 ? -58.273 -4.347  11.858  1.00 87.50  ? 384  ARG E C   1 
ATOM   16495 O O   . ARG E 2 107 ? -57.140 -4.856  11.930  1.00 100.39 ? 384  ARG E O   1 
ATOM   16496 C CB  . ARG E 2 107 ? -60.474 -5.570  11.574  1.00 82.99  ? 384  ARG E CB  1 
ATOM   16497 C CG  . ARG E 2 107 ? -61.637 -6.283  12.277  1.00 89.44  ? 384  ARG E CG  1 
ATOM   16498 C CD  . ARG E 2 107 ? -62.819 -6.605  11.357  1.00 111.35 ? 384  ARG E CD  1 
ATOM   16499 N NE  . ARG E 2 107 ? -62.484 -7.468  10.232  1.00 124.84 ? 384  ARG E NE  1 
ATOM   16500 C CZ  . ARG E 2 107 ? -63.271 -7.657  9.180   1.00 125.79 ? 384  ARG E CZ  1 
ATOM   16501 N NH1 . ARG E 2 107 ? -64.448 -7.061  9.082   1.00 109.66 ? 384  ARG E NH1 1 
ATOM   16502 N NH2 . ARG E 2 107 ? -62.862 -8.457  8.200   1.00 123.47 ? 384  ARG E NH2 1 
ATOM   16503 N N   . LEU E 2 108 ? -58.509 -3.220  11.181  1.00 85.41  ? 385  LEU E N   1 
ATOM   16504 C CA  . LEU E 2 108 ? -57.419 -2.453  10.591  1.00 82.52  ? 385  LEU E CA  1 
ATOM   16505 C C   . LEU E 2 108 ? -56.395 -2.060  11.650  1.00 86.89  ? 385  LEU E C   1 
ATOM   16506 O O   . LEU E 2 108 ? -55.183 -2.156  11.420  1.00 88.43  ? 385  LEU E O   1 
ATOM   16507 C CB  . LEU E 2 108 ? -57.984 -1.211  9.900   1.00 75.34  ? 385  LEU E CB  1 
ATOM   16508 C CG  . LEU E 2 108 ? -58.987 -1.469  8.771   1.00 82.28  ? 385  LEU E CG  1 
ATOM   16509 C CD1 . LEU E 2 108 ? -59.199 -0.216  7.932   1.00 88.60  ? 385  LEU E CD1 1 
ATOM   16510 C CD2 . LEU E 2 108 ? -58.562 -2.642  7.899   1.00 79.01  ? 385  LEU E CD2 1 
ATOM   16511 N N   . LEU E 2 109 ? -56.867 -1.620  12.822  1.00 79.58  ? 386  LEU E N   1 
ATOM   16512 C CA  . LEU E 2 109 ? -55.962 -1.302  13.924  1.00 81.34  ? 386  LEU E CA  1 
ATOM   16513 C C   . LEU E 2 109 ? -55.199 -2.535  14.390  1.00 78.65  ? 386  LEU E C   1 
ATOM   16514 O O   . LEU E 2 109 ? -54.012 -2.447  14.730  1.00 75.42  ? 386  LEU E O   1 
ATOM   16515 C CB  . LEU E 2 109 ? -56.744 -0.699  15.089  1.00 73.20  ? 386  LEU E CB  1 
ATOM   16516 C CG  . LEU E 2 109 ? -55.934 -0.546  16.378  1.00 58.52  ? 386  LEU E CG  1 
ATOM   16517 C CD1 . LEU E 2 109 ? -55.031 0.668   16.307  1.00 61.14  ? 386  LEU E CD1 1 
ATOM   16518 C CD2 . LEU E 2 109 ? -56.848 -0.473  17.589  1.00 70.56  ? 386  LEU E CD2 1 
ATOM   16519 N N   . LYS E 2 110 ? -55.875 -3.687  14.430  1.00 74.91  ? 387  LYS E N   1 
ATOM   16520 C CA  . LYS E 2 110 ? -55.237 -4.929  14.849  1.00 81.53  ? 387  LYS E CA  1 
ATOM   16521 C C   . LYS E 2 110 ? -54.067 -5.272  13.946  1.00 83.43  ? 387  LYS E C   1 
ATOM   16522 O O   . LYS E 2 110 ? -53.067 -5.828  14.404  1.00 96.55  ? 387  LYS E O   1 
ATOM   16523 C CB  . LYS E 2 110 ? -56.265 -6.063  14.859  1.00 92.31  ? 387  LYS E CB  1 
ATOM   16524 C CG  . LYS E 2 110 ? -55.681 -7.473  14.880  1.00 115.35 ? 387  LYS E CG  1 
ATOM   16525 C CD  . LYS E 2 110 ? -54.851 -7.747  16.127  1.00 143.07 ? 387  LYS E CD  1 
ATOM   16526 C CE  . LYS E 2 110 ? -54.266 -9.152  16.097  1.00 166.60 ? 387  LYS E CE  1 
ATOM   16527 N NZ  . LYS E 2 110 ? -53.456 -9.449  17.312  1.00 189.23 ? 387  LYS E NZ  1 
ATOM   16528 N N   . LEU E 2 111 ? -54.175 -4.957  12.656  1.00 73.92  ? 388  LEU E N   1 
ATOM   16529 C CA  . LEU E 2 111 ? -53.019 -5.135  11.776  1.00 78.94  ? 388  LEU E CA  1 
ATOM   16530 C C   . LEU E 2 111 ? -51.798 -4.394  12.333  1.00 80.83  ? 388  LEU E C   1 
ATOM   16531 O O   . LEU E 2 111 ? -50.739 -4.990  12.597  1.00 90.66  ? 388  LEU E O   1 
ATOM   16532 C CB  . LEU E 2 111 ? -53.360 -4.641  10.369  1.00 81.05  ? 388  LEU E CB  1 
ATOM   16533 C CG  . LEU E 2 111 ? -54.659 -5.186  9.767   1.00 72.07  ? 388  LEU E CG  1 
ATOM   16534 C CD1 . LEU E 2 111 ? -54.934 -4.563  8.402   1.00 80.37  ? 388  LEU E CD1 1 
ATOM   16535 C CD2 . LEU E 2 111 ? -54.684 -6.705  9.696   1.00 64.68  ? 388  LEU E CD2 1 
ATOM   16536 N N   . PHE E 2 112 ? -51.955 -3.084  12.553  1.00 77.53  ? 389  PHE E N   1 
ATOM   16537 C CA  . PHE E 2 112 ? -50.883 -2.258  13.103  1.00 72.89  ? 389  PHE E CA  1 
ATOM   16538 C C   . PHE E 2 112 ? -50.361 -2.820  14.420  1.00 74.04  ? 389  PHE E C   1 
ATOM   16539 O O   . PHE E 2 112 ? -49.147 -2.913  14.632  1.00 76.17  ? 389  PHE E O   1 
ATOM   16540 C CB  . PHE E 2 112 ? -51.395 -0.829  13.299  1.00 76.05  ? 389  PHE E CB  1 
ATOM   16541 C CG  . PHE E 2 112 ? -50.326 0.162   13.664  1.00 68.25  ? 389  PHE E CG  1 
ATOM   16542 C CD1 . PHE E 2 112 ? -49.437 0.631   12.713  1.00 70.85  ? 389  PHE E CD1 1 
ATOM   16543 C CD2 . PHE E 2 112 ? -50.213 0.625   14.964  1.00 76.28  ? 389  PHE E CD2 1 
ATOM   16544 C CE1 . PHE E 2 112 ? -48.456 1.547   13.053  1.00 71.23  ? 389  PHE E CE1 1 
ATOM   16545 C CE2 . PHE E 2 112 ? -49.233 1.536   15.310  1.00 62.93  ? 389  PHE E CE2 1 
ATOM   16546 C CZ  . PHE E 2 112 ? -48.354 1.998   14.353  1.00 56.60  ? 389  PHE E CZ  1 
ATOM   16547 N N   . THR E 2 113 ? -51.270 -3.202  15.321  1.00 79.02  ? 390  THR E N   1 
ATOM   16548 C CA  . THR E 2 113 ? -50.851 -3.614  16.660  1.00 78.21  ? 390  THR E CA  1 
ATOM   16549 C C   . THR E 2 113 ? -50.134 -4.959  16.637  1.00 85.77  ? 390  THR E C   1 
ATOM   16550 O O   . THR E 2 113 ? -49.144 -5.148  17.353  1.00 88.66  ? 390  THR E O   1 
ATOM   16551 C CB  . THR E 2 113 ? -52.050 -3.665  17.607  1.00 67.93  ? 390  THR E CB  1 
ATOM   16552 O OG1 . THR E 2 113 ? -52.934 -4.723  17.214  1.00 86.25  ? 390  THR E OG1 1 
ATOM   16553 C CG2 . THR E 2 113 ? -52.794 -2.340  17.603  1.00 63.51  ? 390  THR E CG2 1 
ATOM   16554 N N   . ARG E 2 114 ? -50.621 -5.911  15.835  1.00 85.22  ? 391  ARG E N   1 
ATOM   16555 C CA  . ARG E 2 114 ? -49.945 -7.197  15.740  1.00 88.54  ? 391  ARG E CA  1 
ATOM   16556 C C   . ARG E 2 114 ? -48.566 -7.045  15.122  1.00 93.26  ? 391  ARG E C   1 
ATOM   16557 O O   . ARG E 2 114 ? -47.666 -7.838  15.419  1.00 94.06  ? 391  ARG E O   1 
ATOM   16558 C CB  . ARG E 2 114 ? -50.775 -8.197  14.930  1.00 100.66 ? 391  ARG E CB  1 
ATOM   16559 C CG  . ARG E 2 114 ? -50.973 -7.822  13.472  1.00 100.14 ? 391  ARG E CG  1 
ATOM   16560 C CD  . ARG E 2 114 ? -50.874 -9.034  12.574  1.00 95.92  ? 391  ARG E CD  1 
ATOM   16561 N NE  . ARG E 2 114 ? -51.662 -8.932  11.352  1.00 78.66  ? 391  ARG E NE  1 
ATOM   16562 C CZ  . ARG E 2 114 ? -51.280 -8.269  10.269  1.00 86.64  ? 391  ARG E CZ  1 
ATOM   16563 N NH1 . ARG E 2 114 ? -50.169 -7.550  10.253  1.00 92.80  ? 391  ARG E NH1 1 
ATOM   16564 N NH2 . ARG E 2 114 ? -52.024 -8.339  9.170   1.00 91.92  ? 391  ARG E NH2 1 
ATOM   16565 N N   . CYS E 2 115 ? -48.370 -6.040  14.264  1.00 96.52  ? 392  CYS E N   1 
ATOM   16566 C CA  . CYS E 2 115 ? -47.004 -5.788  13.820  1.00 86.57  ? 392  CYS E CA  1 
ATOM   16567 C C   . CYS E 2 115 ? -46.167 -5.094  14.891  1.00 89.12  ? 392  CYS E C   1 
ATOM   16568 O O   . CYS E 2 115 ? -44.934 -5.144  14.824  1.00 103.95 ? 392  CYS E O   1 
ATOM   16569 C CB  . CYS E 2 115 ? -47.005 -4.981  12.527  1.00 87.78  ? 392  CYS E CB  1 
ATOM   16570 S SG  . CYS E 2 115 ? -47.811 -5.845  11.168  1.00 100.24 ? 392  CYS E SG  1 
ATOM   16571 N N   . LEU E 2 116 ? -46.799 -4.461  15.876  1.00 99.02  ? 393  LEU E N   1 
ATOM   16572 C CA  . LEU E 2 116 ? -46.056 -3.823  16.954  1.00 106.37 ? 393  LEU E CA  1 
ATOM   16573 C C   . LEU E 2 116 ? -45.440 -4.870  17.877  1.00 114.83 ? 393  LEU E C   1 
ATOM   16574 O O   . LEU E 2 116 ? -46.004 -5.946  18.096  1.00 121.69 ? 393  LEU E O   1 
ATOM   16575 C CB  . LEU E 2 116 ? -46.964 -2.893  17.759  1.00 98.15  ? 393  LEU E CB  1 
ATOM   16576 C CG  . LEU E 2 116 ? -47.424 -1.588  17.108  1.00 88.66  ? 393  LEU E CG  1 
ATOM   16577 C CD1 . LEU E 2 116 ? -48.187 -0.748  18.114  1.00 87.60  ? 393  LEU E CD1 1 
ATOM   16578 C CD2 . LEU E 2 116 ? -46.246 -0.808  16.551  1.00 81.45  ? 393  LEU E CD2 1 
ATOM   16579 N N   . THR E 2 117 ? -44.271 -4.538  18.419  1.00 111.92 ? 394  THR E N   1 
ATOM   16580 C CA  . THR E 2 117 ? -43.549 -5.395  19.360  1.00 124.67 ? 394  THR E CA  1 
ATOM   16581 C C   . THR E 2 117 ? -43.273 -6.781  18.786  1.00 117.87 ? 394  THR E C   1 
ATOM   16582 O O   . THR E 2 117 ? -42.119 -7.196  18.676  1.00 97.94  ? 394  THR E O   1 
ATOM   16583 C CB  . THR E 2 117 ? -44.318 -5.549  20.687  1.00 138.18 ? 394  THR E CB  1 
ATOM   16584 O OG1 . THR E 2 117 ? -44.661 -4.254  21.197  1.00 149.46 ? 394  THR E OG1 1 
ATOM   16585 C CG2 . THR E 2 117 ? -43.465 -6.283  21.709  1.00 129.14 ? 394  THR E CG2 1 
ATOM   16586 N N   . ASP F 3 8   ? -59.783 46.035  64.551  1.00 88.84  ? 224  ASP F N   1 
ATOM   16587 C CA  . ASP F 3 8   ? -59.322 46.438  65.875  1.00 81.74  ? 224  ASP F CA  1 
ATOM   16588 C C   . ASP F 3 8   ? -58.761 45.231  66.621  1.00 81.09  ? 224  ASP F C   1 
ATOM   16589 O O   . ASP F 3 8   ? -57.548 45.106  66.785  1.00 94.89  ? 224  ASP F O   1 
ATOM   16590 C CB  . ASP F 3 8   ? -60.458 47.082  66.670  1.00 86.35  ? 224  ASP F CB  1 
ATOM   16591 C CG  . ASP F 3 8   ? -59.988 47.672  67.983  1.00 93.66  ? 224  ASP F CG  1 
ATOM   16592 O OD1 . ASP F 3 8   ? -59.083 48.532  67.954  1.00 89.15  ? 224  ASP F OD1 1 
ATOM   16593 O OD2 . ASP F 3 8   ? -60.523 47.279  69.041  1.00 105.58 ? 224  ASP F OD2 1 
ATOM   16594 N N   . GLU F 3 9   ? -59.654 44.347  67.079  1.00 83.35  ? 225  GLU F N   1 
ATOM   16595 C CA  . GLU F 3 9   ? -59.209 43.068  67.627  1.00 76.22  ? 225  GLU F CA  1 
ATOM   16596 C C   . GLU F 3 9   ? -58.426 42.269  66.595  1.00 78.55  ? 225  GLU F C   1 
ATOM   16597 O O   . GLU F 3 9   ? -57.386 41.678  66.915  1.00 77.51  ? 225  GLU F O   1 
ATOM   16598 C CB  . GLU F 3 9   ? -60.407 42.261  68.129  1.00 65.73  ? 225  GLU F CB  1 
ATOM   16599 C CG  . GLU F 3 9   ? -60.771 42.507  69.580  1.00 61.77  ? 225  GLU F CG  1 
ATOM   16600 C CD  . GLU F 3 9   ? -59.925 41.673  70.529  1.00 83.97  ? 225  GLU F CD  1 
ATOM   16601 O OE1 . GLU F 3 9   ? -58.707 41.931  70.639  1.00 71.15  ? 225  GLU F OE1 1 
ATOM   16602 O OE2 . GLU F 3 9   ? -60.478 40.746  71.155  1.00 102.02 ? 225  GLU F OE2 1 
ATOM   16603 N N   . TYR F 3 10  ? -58.902 42.246  65.352  1.00 74.20  ? 226  TYR F N   1 
ATOM   16604 C CA  . TYR F 3 10  ? -58.254 41.482  64.295  1.00 82.44  ? 226  TYR F CA  1 
ATOM   16605 C C   . TYR F 3 10  ? -57.055 42.201  63.686  1.00 85.44  ? 226  TYR F C   1 
ATOM   16606 O O   . TYR F 3 10  ? -56.450 41.675  62.746  1.00 98.78  ? 226  TYR F O   1 
ATOM   16607 C CB  . TYR F 3 10  ? -59.275 41.130  63.208  1.00 63.89  ? 226  TYR F CB  1 
ATOM   16608 C CG  . TYR F 3 10  ? -60.408 40.261  63.715  1.00 60.36  ? 226  TYR F CG  1 
ATOM   16609 C CD1 . TYR F 3 10  ? -60.148 39.095  64.424  1.00 60.51  ? 226  TYR F CD1 1 
ATOM   16610 C CD2 . TYR F 3 10  ? -61.733 40.607  63.489  1.00 78.86  ? 226  TYR F CD2 1 
ATOM   16611 C CE1 . TYR F 3 10  ? -61.176 38.297  64.893  1.00 59.59  ? 226  TYR F CE1 1 
ATOM   16612 C CE2 . TYR F 3 10  ? -62.770 39.813  63.954  1.00 82.81  ? 226  TYR F CE2 1 
ATOM   16613 C CZ  . TYR F 3 10  ? -62.483 38.659  64.656  1.00 70.55  ? 226  TYR F CZ  1 
ATOM   16614 O OH  . TYR F 3 10  ? -63.504 37.863  65.122  1.00 77.89  ? 226  TYR F OH  1 
ATOM   16615 N N   . GLU F 3 11  ? -56.699 43.382  64.190  1.00 78.64  ? 227  GLU F N   1 
ATOM   16616 C CA  . GLU F 3 11  ? -55.433 44.010  63.835  1.00 83.32  ? 227  GLU F CA  1 
ATOM   16617 C C   . GLU F 3 11  ? -54.317 43.412  64.679  1.00 68.89  ? 227  GLU F C   1 
ATOM   16618 O O   . GLU F 3 11  ? -54.423 43.349  65.908  1.00 83.85  ? 227  GLU F O   1 
ATOM   16619 C CB  . GLU F 3 11  ? -55.492 45.521  64.049  1.00 99.33  ? 227  GLU F CB  1 
ATOM   16620 C CG  . GLU F 3 11  ? -56.383 46.276  63.084  1.00 123.21 ? 227  GLU F CG  1 
ATOM   16621 C CD  . GLU F 3 11  ? -55.630 47.386  62.375  1.00 138.66 ? 227  GLU F CD  1 
ATOM   16622 O OE1 . GLU F 3 11  ? -54.608 47.088  61.723  1.00 130.16 ? 227  GLU F OE1 1 
ATOM   16623 O OE2 . GLU F 3 11  ? -56.042 48.559  62.489  1.00 141.21 ? 227  GLU F OE2 1 
ATOM   16624 N N   . PHE F 3 12  ? -53.242 42.983  64.024  1.00 71.61  ? 228  PHE F N   1 
ATOM   16625 C CA  . PHE F 3 12  ? -52.168 42.293  64.723  1.00 78.13  ? 228  PHE F CA  1 
ATOM   16626 C C   . PHE F 3 12  ? -51.231 43.297  65.383  1.00 80.82  ? 228  PHE F C   1 
ATOM   16627 O O   . PHE F 3 12  ? -50.809 44.273  64.754  1.00 95.45  ? 228  PHE F O   1 
ATOM   16628 C CB  . PHE F 3 12  ? -51.384 41.396  63.769  1.00 60.66  ? 228  PHE F CB  1 
ATOM   16629 C CG  . PHE F 3 12  ? -50.201 40.737  64.410  1.00 65.24  ? 228  PHE F CG  1 
ATOM   16630 C CD1 . PHE F 3 12  ? -50.383 39.764  65.376  1.00 77.42  ? 228  PHE F CD1 1 
ATOM   16631 C CD2 . PHE F 3 12  ? -48.912 41.106  64.072  1.00 71.08  ? 228  PHE F CD2 1 
ATOM   16632 C CE1 . PHE F 3 12  ? -49.302 39.157  65.980  1.00 72.38  ? 228  PHE F CE1 1 
ATOM   16633 C CE2 . PHE F 3 12  ? -47.826 40.502  64.676  1.00 71.71  ? 228  PHE F CE2 1 
ATOM   16634 C CZ  . PHE F 3 12  ? -48.024 39.526  65.631  1.00 60.58  ? 228  PHE F CZ  1 
ATOM   16635 N N   . ASP F 3 13  ? -50.900 43.045  66.650  1.00 79.65  ? 229  ASP F N   1 
ATOM   16636 C CA  . ASP F 3 13  ? -50.012 43.930  67.410  1.00 86.72  ? 229  ASP F CA  1 
ATOM   16637 C C   . ASP F 3 13  ? -49.559 43.154  68.651  1.00 91.99  ? 229  ASP F C   1 
ATOM   16638 O O   . ASP F 3 13  ? -50.228 43.181  69.684  1.00 122.61 ? 229  ASP F O   1 
ATOM   16639 C CB  . ASP F 3 13  ? -50.698 45.226  67.789  1.00 93.17  ? 229  ASP F CB  1 
ATOM   16640 C CG  . ASP F 3 13  ? -49.751 46.226  68.425  1.00 109.40 ? 229  ASP F CG  1 
ATOM   16641 O OD1 . ASP F 3 13  ? -48.771 46.628  67.764  1.00 117.47 ? 229  ASP F OD1 1 
ATOM   16642 O OD2 . ASP F 3 13  ? -49.989 46.608  69.591  1.00 123.10 ? 229  ASP F OD2 1 
ATOM   16643 N N   . GLU F 3 14  ? -48.425 42.468  68.531  1.00 69.16  ? 230  GLU F N   1 
ATOM   16644 C CA  . GLU F 3 14  ? -47.926 41.639  69.617  1.00 71.55  ? 230  GLU F CA  1 
ATOM   16645 C C   . GLU F 3 14  ? -46.413 41.772  69.719  1.00 91.23  ? 230  GLU F C   1 
ATOM   16646 O O   . GLU F 3 14  ? -45.743 42.257  68.804  1.00 96.94  ? 230  GLU F O   1 
ATOM   16647 C CB  . GLU F 3 14  ? -48.329 40.170  69.432  1.00 87.46  ? 230  GLU F CB  1 
ATOM   16648 C CG  . GLU F 3 14  ? -49.799 39.901  69.710  1.00 86.27  ? 230  GLU F CG  1 
ATOM   16649 C CD  . GLU F 3 14  ? -50.118 38.425  69.785  1.00 80.25  ? 230  GLU F CD  1 
ATOM   16650 O OE1 . GLU F 3 14  ? -49.171 37.611  69.740  1.00 75.03  ? 230  GLU F OE1 1 
ATOM   16651 O OE2 . GLU F 3 14  ? -51.314 38.080  69.892  1.00 70.82  ? 230  GLU F OE2 1 
ATOM   16652 N N   . ASP F 3 15  ? -45.886 41.320  70.854  1.00 91.55  ? 231  ASP F N   1 
ATOM   16653 C CA  . ASP F 3 15  ? -44.478 41.484  71.180  1.00 89.28  ? 231  ASP F CA  1 
ATOM   16654 C C   . ASP F 3 15  ? -43.607 40.558  70.336  1.00 88.29  ? 231  ASP F C   1 
ATOM   16655 O O   . ASP F 3 15  ? -44.085 39.619  69.694  1.00 82.50  ? 231  ASP F O   1 
ATOM   16656 C CB  . ASP F 3 15  ? -44.242 41.195  72.661  1.00 98.72  ? 231  ASP F CB  1 
ATOM   16657 C CG  . ASP F 3 15  ? -44.705 42.321  73.559  1.00 107.89 ? 231  ASP F CG  1 
ATOM   16658 O OD1 . ASP F 3 15  ? -45.355 43.258  73.051  1.00 124.57 ? 231  ASP F OD1 1 
ATOM   16659 O OD2 . ASP F 3 15  ? -44.428 42.262  74.775  1.00 115.91 ? 231  ASP F OD2 1 
ATOM   16660 N N   . ASP F 3 16  ? -42.301 40.831  70.357  1.00 84.98  ? 232  ASP F N   1 
ATOM   16661 C CA  . ASP F 3 16  ? -41.324 39.997  69.667  1.00 79.38  ? 232  ASP F CA  1 
ATOM   16662 C C   . ASP F 3 16  ? -40.352 39.361  70.653  1.00 85.76  ? 232  ASP F C   1 
ATOM   16663 O O   . ASP F 3 16  ? -39.134 39.444  70.468  1.00 115.81 ? 232  ASP F O   1 
ATOM   16664 C CB  . ASP F 3 16  ? -40.552 40.810  68.624  1.00 76.55  ? 232  ASP F CB  1 
ATOM   16665 C CG  . ASP F 3 16  ? -41.449 41.383  67.546  1.00 85.69  ? 232  ASP F CG  1 
ATOM   16666 O OD1 . ASP F 3 16  ? -42.399 42.118  67.888  1.00 109.30 ? 232  ASP F OD1 1 
ATOM   16667 O OD2 . ASP F 3 16  ? -41.202 41.093  66.355  1.00 74.23  ? 232  ASP F OD2 1 
ATOM   16668 N N   . GLU F 3 17  ? -40.882 38.743  71.711  1.00 83.10  ? 233  GLU F N   1 
ATOM   16669 C CA  . GLU F 3 17  ? -40.094 37.996  72.691  1.00 90.80  ? 233  GLU F CA  1 
ATOM   16670 C C   . GLU F 3 17  ? -39.155 38.895  73.491  1.00 97.33  ? 233  GLU F C   1 
ATOM   16671 O O   . GLU F 3 17  ? -39.153 38.846  74.725  1.00 106.60 ? 233  GLU F O   1 
ATOM   16672 C CB  . GLU F 3 17  ? -39.299 36.881  72.004  1.00 93.55  ? 233  GLU F CB  1 
ATOM   16673 C CG  . GLU F 3 17  ? -38.574 35.940  72.950  1.00 94.03  ? 233  GLU F CG  1 
ATOM   16674 C CD  . GLU F 3 17  ? -38.013 34.730  72.231  1.00 110.18 ? 233  GLU F CD  1 
ATOM   16675 O OE1 . GLU F 3 17  ? -38.812 33.868  71.809  1.00 115.05 ? 233  GLU F OE1 1 
ATOM   16676 O OE2 . GLU F 3 17  ? -36.774 34.642  72.085  1.00 112.57 ? 233  GLU F OE2 1 
ATOM   16677 N N   . GLN F 3 18  ? -38.345 39.707  72.806  1.00 110.79 ? 234  GLN F N   1 
ATOM   16678 C CA  . GLN F 3 18  ? -37.433 40.603  73.511  1.00 97.50  ? 234  GLN F CA  1 
ATOM   16679 C C   . GLN F 3 18  ? -38.188 41.640  74.335  1.00 102.54 ? 234  GLN F C   1 
ATOM   16680 O O   . GLN F 3 18  ? -37.688 42.092  75.371  1.00 104.81 ? 234  GLN F O   1 
ATOM   16681 C CB  . GLN F 3 18  ? -36.490 41.291  72.522  1.00 91.20  ? 234  GLN F CB  1 
ATOM   16682 C CG  . GLN F 3 18  ? -35.294 40.444  72.107  1.00 125.43 ? 234  GLN F CG  1 
ATOM   16683 C CD  . GLN F 3 18  ? -35.685 39.236  71.278  1.00 123.05 ? 234  GLN F CD  1 
ATOM   16684 O OE1 . GLN F 3 18  ? -36.215 39.372  70.177  1.00 128.68 ? 234  GLN F OE1 1 
ATOM   16685 N NE2 . GLN F 3 18  ? -35.418 38.044  71.803  1.00 107.85 ? 234  GLN F NE2 1 
ATOM   16686 N N   . ASP F 3 19  ? -39.389 42.027  73.897  1.00 104.17 ? 235  ASP F N   1 
ATOM   16687 C CA  . ASP F 3 19  ? -40.202 42.943  74.690  1.00 95.37  ? 235  ASP F CA  1 
ATOM   16688 C C   . ASP F 3 19  ? -40.663 42.299  75.991  1.00 100.04 ? 235  ASP F C   1 
ATOM   16689 O O   . ASP F 3 19  ? -40.909 43.006  76.975  1.00 105.63 ? 235  ASP F O   1 
ATOM   16690 C CB  . ASP F 3 19  ? -41.417 43.410  73.887  1.00 111.63 ? 235  ASP F CB  1 
ATOM   16691 C CG  . ASP F 3 19  ? -41.067 43.803  72.468  1.00 108.64 ? 235  ASP F CG  1 
ATOM   16692 O OD1 . ASP F 3 19  ? -40.537 42.952  71.725  1.00 113.25 ? 235  ASP F OD1 1 
ATOM   16693 O OD2 . ASP F 3 19  ? -41.333 44.965  72.094  1.00 95.15  ? 235  ASP F OD2 1 
ATOM   16694 N N   . ARG F 3 20  ? -40.775 40.973  76.017  1.00 106.01 ? 236  ARG F N   1 
ATOM   16695 C CA  . ARG F 3 20  ? -41.383 40.281  77.143  1.00 111.12 ? 236  ARG F CA  1 
ATOM   16696 C C   . ARG F 3 20  ? -40.538 40.428  78.403  1.00 113.63 ? 236  ARG F C   1 
ATOM   16697 O O   . ARG F 3 20  ? -39.318 40.608  78.347  1.00 116.66 ? 236  ARG F O   1 
ATOM   16698 C CB  . ARG F 3 20  ? -41.571 38.801  76.816  1.00 104.97 ? 236  ARG F CB  1 
ATOM   16699 C CG  . ARG F 3 20  ? -43.023 38.387  76.658  1.00 107.12 ? 236  ARG F CG  1 
ATOM   16700 C CD  . ARG F 3 20  ? -43.639 39.106  75.474  1.00 114.93 ? 236  ARG F CD  1 
ATOM   16701 N NE  . ARG F 3 20  ? -43.195 38.533  74.210  1.00 114.28 ? 236  ARG F NE  1 
ATOM   16702 C CZ  . ARG F 3 20  ? -43.866 37.613  73.533  1.00 115.99 ? 236  ARG F CZ  1 
ATOM   16703 N NH1 . ARG F 3 20  ? -45.055 37.192  73.931  1.00 133.89 ? 236  ARG F NH1 1 
ATOM   16704 N NH2 . ARG F 3 20  ? -43.334 37.107  72.423  1.00 95.58  ? 236  ARG F NH2 1 
ATOM   16705 N N   . VAL F 3 21  ? -41.205 40.340  79.550  1.00 110.58 ? 237  VAL F N   1 
ATOM   16706 C CA  . VAL F 3 21  ? -40.545 40.426  80.849  1.00 108.97 ? 237  VAL F CA  1 
ATOM   16707 C C   . VAL F 3 21  ? -40.428 39.023  81.439  1.00 111.42 ? 237  VAL F C   1 
ATOM   16708 O O   . VAL F 3 21  ? -41.281 38.164  81.170  1.00 116.60 ? 237  VAL F O   1 
ATOM   16709 C CB  . VAL F 3 21  ? -41.297 41.383  81.790  1.00 112.12 ? 237  VAL F CB  1 
ATOM   16710 C CG1 . VAL F 3 21  ? -41.423 42.756  81.151  1.00 109.98 ? 237  VAL F CG1 1 
ATOM   16711 C CG2 . VAL F 3 21  ? -42.672 40.832  82.130  1.00 105.37 ? 237  VAL F CG2 1 
ATOM   16712 N N   . PRO F 3 22  ? -39.398 38.743  82.233  1.00 102.25 ? 238  PRO F N   1 
ATOM   16713 C CA  . PRO F 3 22  ? -39.178 37.377  82.723  1.00 104.82 ? 238  PRO F CA  1 
ATOM   16714 C C   . PRO F 3 22  ? -40.204 36.988  83.775  1.00 119.22 ? 238  PRO F C   1 
ATOM   16715 O O   . PRO F 3 22  ? -40.936 37.847  84.290  1.00 124.81 ? 238  PRO F O   1 
ATOM   16716 C CB  . PRO F 3 22  ? -37.760 37.452  83.307  1.00 115.98 ? 238  PRO F CB  1 
ATOM   16717 C CG  . PRO F 3 22  ? -37.657 38.861  83.779  1.00 129.59 ? 238  PRO F CG  1 
ATOM   16718 C CD  . PRO F 3 22  ? -38.338 39.659  82.694  1.00 119.66 ? 238  PRO F CD  1 
ATOM   16719 N N   . PRO F 3 23  ? -40.299 35.695  84.116  1.00 120.38 ? 239  PRO F N   1 
ATOM   16720 C CA  . PRO F 3 23  ? -41.385 35.248  85.004  1.00 117.52 ? 239  PRO F CA  1 
ATOM   16721 C C   . PRO F 3 23  ? -41.159 35.528  86.481  1.00 122.49 ? 239  PRO F C   1 
ATOM   16722 O O   . PRO F 3 23  ? -42.128 35.444  87.249  1.00 140.30 ? 239  PRO F O   1 
ATOM   16723 C CB  . PRO F 3 23  ? -41.445 33.739  84.737  1.00 119.77 ? 239  PRO F CB  1 
ATOM   16724 C CG  . PRO F 3 23  ? -40.036 33.391  84.405  1.00 133.71 ? 239  PRO F CG  1 
ATOM   16725 C CD  . PRO F 3 23  ? -39.543 34.550  83.573  1.00 128.15 ? 239  PRO F CD  1 
ATOM   16726 N N   . VAL F 3 24  ? -39.925 35.820  86.901  1.00 114.03 ? 240  VAL F N   1 
ATOM   16727 C CA  . VAL F 3 24  ? -39.583 36.221  88.267  1.00 118.93 ? 240  VAL F CA  1 
ATOM   16728 C C   . VAL F 3 24  ? -39.610 35.035  89.227  1.00 121.37 ? 240  VAL F C   1 
ATOM   16729 O O   . VAL F 3 24  ? -38.657 34.825  89.986  1.00 109.10 ? 240  VAL F O   1 
ATOM   16730 C CB  . VAL F 3 24  ? -40.498 37.355  88.773  1.00 126.92 ? 240  VAL F CB  1 
ATOM   16731 C CG1 . VAL F 3 24  ? -40.312 37.568  90.268  1.00 115.77 ? 240  VAL F CG1 1 
ATOM   16732 C CG2 . VAL F 3 24  ? -40.228 38.639  88.002  1.00 140.40 ? 240  VAL F CG2 1 
ATOM   16733 N N   . ASP F 3 25  ? -40.687 34.254  89.218  1.00 128.53 ? 241  ASP F N   1 
ATOM   16734 C CA  . ASP F 3 25  ? -40.831 33.155  90.162  1.00 118.06 ? 241  ASP F CA  1 
ATOM   16735 C C   . ASP F 3 25  ? -41.233 31.876  89.439  1.00 120.65 ? 241  ASP F C   1 
ATOM   16736 O O   . ASP F 3 25  ? -41.572 31.879  88.251  1.00 112.94 ? 241  ASP F O   1 
ATOM   16737 C CB  . ASP F 3 25  ? -41.854 33.491  91.256  1.00 135.76 ? 241  ASP F CB  1 
ATOM   16738 C CG  . ASP F 3 25  ? -43.205 33.871  90.690  1.00 153.61 ? 241  ASP F CG  1 
ATOM   16739 O OD1 . ASP F 3 25  ? -43.266 34.825  89.885  1.00 159.64 ? 241  ASP F OD1 1 
ATOM   16740 O OD2 . ASP F 3 25  ? -44.205 33.216  91.048  1.00 154.66 ? 241  ASP F OD2 1 
ATOM   16741 N N   . ASP F 3 26  ? -41.188 30.769  90.185  1.00 122.02 ? 242  ASP F N   1 
ATOM   16742 C CA  . ASP F 3 26  ? -41.558 29.466  89.642  1.00 116.22 ? 242  ASP F CA  1 
ATOM   16743 C C   . ASP F 3 26  ? -43.061 29.229  89.730  1.00 117.22 ? 242  ASP F C   1 
ATOM   16744 O O   . ASP F 3 26  ? -43.687 28.801  88.756  1.00 127.99 ? 242  ASP F O   1 
ATOM   16745 C CB  . ASP F 3 26  ? -40.804 28.358  90.380  1.00 102.96 ? 242  ASP F CB  1 
ATOM   16746 C CG  . ASP F 3 26  ? -41.329 26.977  90.049  1.00 120.97 ? 242  ASP F CG  1 
ATOM   16747 O OD1 . ASP F 3 26  ? -41.381 26.637  88.852  1.00 139.21 ? 242  ASP F OD1 1 
ATOM   16748 O OD2 . ASP F 3 26  ? -41.694 26.234  90.983  1.00 144.12 ? 242  ASP F OD2 1 
ATOM   16749 N N   . LYS F 3 27  ? -43.650 29.496  90.895  1.00 120.94 ? 243  LYS F N   1 
ATOM   16750 C CA  . LYS F 3 27  ? -45.068 29.249  91.136  1.00 96.05  ? 243  LYS F CA  1 
ATOM   16751 C C   . LYS F 3 27  ? -45.924 30.173  90.274  1.00 100.51 ? 243  LYS F C   1 
ATOM   16752 O O   . LYS F 3 27  ? -46.268 31.279  90.698  1.00 104.19 ? 243  LYS F O   1 
ATOM   16753 C CB  . LYS F 3 27  ? -45.379 29.450  92.621  1.00 96.02  ? 243  LYS F CB  1 
ATOM   16754 C CG  . LYS F 3 27  ? -44.691 28.444  93.546  1.00 60.57  ? 243  LYS F CG  1 
ATOM   16755 C CD  . LYS F 3 27  ? -45.381 27.090  93.554  1.00 99.30  ? 243  LYS F CD  1 
ATOM   16756 C CE  . LYS F 3 27  ? -44.387 25.941  93.601  1.00 119.65 ? 243  LYS F CE  1 
ATOM   16757 N NZ  . LYS F 3 27  ? -43.755 25.701  92.275  1.00 154.82 ? 243  LYS F NZ  1 
ATOM   16758 N N   . HIS F 3 28  ? -46.280 29.726  89.065  1.00 101.26 ? 244  HIS F N   1 
ATOM   16759 C CA  . HIS F 3 28  ? -46.865 30.637  88.082  1.00 90.30  ? 244  HIS F CA  1 
ATOM   16760 C C   . HIS F 3 28  ? -48.297 31.031  88.426  1.00 88.69  ? 244  HIS F C   1 
ATOM   16761 O O   . HIS F 3 28  ? -48.712 32.158  88.129  1.00 87.00  ? 244  HIS F O   1 
ATOM   16762 C CB  . HIS F 3 28  ? -46.818 30.019  86.683  1.00 86.45  ? 244  HIS F CB  1 
ATOM   16763 C CG  . HIS F 3 28  ? -45.525 30.243  85.961  1.00 107.84 ? 244  HIS F CG  1 
ATOM   16764 N ND1 . HIS F 3 28  ? -44.306 29.829  86.456  1.00 139.42 ? 244  HIS F ND1 1 
ATOM   16765 C CD2 . HIS F 3 28  ? -45.262 30.848  84.778  1.00 104.76 ? 244  HIS F CD2 1 
ATOM   16766 C CE1 . HIS F 3 28  ? -43.350 30.162  85.606  1.00 151.23 ? 244  HIS F CE1 1 
ATOM   16767 N NE2 . HIS F 3 28  ? -43.904 30.783  84.580  1.00 160.36 ? 244  HIS F NE2 1 
ATOM   16768 N N   . LEU F 3 29  ? -49.074 30.128  89.029  1.00 90.30  ? 245  LEU F N   1 
ATOM   16769 C CA  . LEU F 3 29  ? -50.476 30.444  89.294  1.00 85.16  ? 245  LEU F CA  1 
ATOM   16770 C C   . LEU F 3 29  ? -50.604 31.609  90.270  1.00 104.45 ? 245  LEU F C   1 
ATOM   16771 O O   . LEU F 3 29  ? -51.513 32.440  90.138  1.00 105.10 ? 245  LEU F O   1 
ATOM   16772 C CB  . LEU F 3 29  ? -51.211 29.208  89.812  1.00 71.74  ? 245  LEU F CB  1 
ATOM   16773 C CG  . LEU F 3 29  ? -52.045 28.446  88.775  1.00 74.26  ? 245  LEU F CG  1 
ATOM   16774 C CD1 . LEU F 3 29  ? -53.350 29.178  88.498  1.00 96.53  ? 245  LEU F CD1 1 
ATOM   16775 C CD2 . LEU F 3 29  ? -51.272 28.229  87.485  1.00 66.86  ? 245  LEU F CD2 1 
ATOM   16776 N N   . LEU F 3 30  ? -49.699 31.687  91.247  1.00 110.28 ? 246  LEU F N   1 
ATOM   16777 C CA  . LEU F 3 30  ? -49.551 32.837  92.153  1.00 105.45 ? 246  LEU F CA  1 
ATOM   16778 C C   . LEU F 3 30  ? -50.888 33.082  92.850  1.00 117.84 ? 246  LEU F C   1 
ATOM   16779 O O   . LEU F 3 30  ? -51.411 32.158  93.495  1.00 127.75 ? 246  LEU F O   1 
ATOM   16780 C CB  . LEU F 3 30  ? -48.997 34.017  91.364  1.00 117.02 ? 246  LEU F CB  1 
ATOM   16781 C CG  . LEU F 3 30  ? -47.478 34.199  91.321  1.00 122.88 ? 246  LEU F CG  1 
ATOM   16782 C CD1 . LEU F 3 30  ? -47.122 35.511  90.643  1.00 119.87 ? 246  LEU F CD1 1 
ATOM   16783 C CD2 . LEU F 3 30  ? -46.893 34.150  92.725  1.00 122.88 ? 246  LEU F CD2 1 
ATOM   16784 N N   . LYS F 3 31  ? -51.466 34.276  92.748  1.00 126.65 ? 247  LYS F N   1 
ATOM   16785 C CA  . LYS F 3 31  ? -52.738 34.616  93.376  1.00 132.40 ? 247  LYS F CA  1 
ATOM   16786 C C   . LYS F 3 31  ? -53.861 33.672  92.956  1.00 130.04 ? 247  LYS F C   1 
ATOM   16787 O O   . LYS F 3 31  ? -54.500 33.039  93.797  1.00 119.63 ? 247  LYS F O   1 
ATOM   16788 C CB  . LYS F 3 31  ? -53.111 36.058  93.029  1.00 122.74 ? 247  LYS F CB  1 
ATOM   16789 C CG  . LYS F 3 31  ? -52.043 37.082  93.389  1.00 114.60 ? 247  LYS F CG  1 
ATOM   16790 C CD  . LYS F 3 31  ? -52.426 38.474  92.906  1.00 116.08 ? 247  LYS F CD  1 
ATOM   16791 C CE  . LYS F 3 31  ? -53.799 38.890  93.412  1.00 119.99 ? 247  LYS F CE  1 
ATOM   16792 N NZ  . LYS F 3 31  ? -54.257 40.153  92.766  1.00 126.21 ? 247  LYS F NZ  1 
HETATM 16793 O O   . HOH G 4 .   ? 51.522  21.227  52.339  1.00 49.01  ? 1101 HOH A O   1 
HETATM 16794 O O   . HOH G 4 .   ? 76.802  34.542  65.226  1.00 46.13  ? 1102 HOH A O   1 
HETATM 16795 O O   . HOH G 4 .   ? 22.454  29.464  61.656  1.00 62.10  ? 1103 HOH A O   1 
HETATM 16796 O O   . HOH G 4 .   ? -14.681 18.522  54.658  1.00 50.62  ? 1104 HOH A O   1 
HETATM 16797 O O   . HOH G 4 .   ? 57.479  21.968  69.573  1.00 44.09  ? 1105 HOH A O   1 
HETATM 16798 O O   . HOH G 4 .   ? 73.082  38.291  60.318  1.00 56.45  ? 1106 HOH A O   1 
HETATM 16799 O O   . HOH H 4 .   ? 71.627  42.842  60.244  1.00 55.76  ? 301  HOH C O   1 
HETATM 16800 O O   . HOH I 4 .   ? -35.089 8.952   73.202  1.00 59.52  ? 1101 HOH D O   1 
HETATM 16801 O O   . HOH I 4 .   ? -50.577 20.105  53.168  1.00 35.94  ? 1102 HOH D O   1 
HETATM 16802 O O   . HOH I 4 .   ? -67.221 2.321   28.065  1.00 85.45  ? 1103 HOH D O   1 
HETATM 16803 O O   . HOH I 4 .   ? -57.922 36.147  74.876  1.00 47.00  ? 1104 HOH D O   1 
HETATM 16804 O O   . HOH I 4 .   ? -67.555 20.048  59.913  1.00 52.58  ? 1105 HOH D O   1 
HETATM 16805 O O   . HOH I 4 .   ? -86.786 34.377  87.441  1.00 89.91  ? 1106 HOH D O   1 
HETATM 16806 O O   . HOH J 4 .   ? -40.010 -5.839  18.090  1.00 85.62  ? 501  HOH E O   1 
# 
