data_9IZC
# 
_entry.id   9IZC 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9IZC         pdb_00009izc 10.2210/pdb9izc/pdb 
WWPDB D_1300049872 ?            ?                   
EMDB  EMD-61028    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-02 ? 
2 'EM metadata'     1 0 2025-04-02 ? 
3 'Half map'        1 0 2025-04-02 1 
4 'Half map'        1 0 2025-04-02 2 
5 Image             1 0 2025-04-02 ? 
6 'Primary map'     1 0 2025-04-02 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9IZC 
_pdbx_database_status.recvd_initial_deposition_date   2024-08-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'protein complex-yanligand1'                              EMD-35483 'other EM volume'      
EMDB 'Cryo-EM structure of human HCAR2-Gi complex with MK1903' EMD-61028 'associated EM volume' 
# 
_pdbx_contact_author.id                 5 
_pdbx_contact_author.email              xinpanphd@163.com 
_pdbx_contact_author.name_first         Xin 
_pdbx_contact_author.name_last          Pan 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1190-4796 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xin, P.'  1 ? 
'Fang, Y.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of human HCAR2-Gi complex with MK1903' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xin, P.'  1 ? 
primary 'Fang, Y.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Hydroxycarboxylic acid receptor 2'                                                            34251.973 1 ? ? ? 
? 
2 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'                             37069.543 1 ? ? ? 
? 
3 polymer     man 'Guanine nucleotide-binding protein G(i) subunit alpha-1'                                      40153.672 1 ? 
'G203A, A326S' ? ? 
4 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'                            6218.162  1 ? ? ? 
? 
5 polymer     man scFv16                                                                                         26424.385 1 ? ? ? 
? 
6 non-polymer syn '(4aR,5aR)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid' 164.161   1 ? ? ? 
? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'G-protein coupled receptor 109A,G-protein coupled receptor HM74A,Niacin receptor 1,Nicotinic acid receptor' 
3 'Adenylate cyclase-inhibiting G alpha protein'                                                               
4 'G gamma-I'                                                                                                  
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;DHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNY
VRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKM
PIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPS
VVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF
;
;DHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNY
VRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKM
PIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPS
VVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF
;
A ? 
2 'polypeptide(L)' no no 
;LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD
SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD
TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT
GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDD
GMAVATGSWDSFLKIWN
;
;LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD
SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD
TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT
GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDD
GMAVATGSWDSFLKIWN
;
B ? 
3 'polypeptide(L)' no no 
;TLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIA
IIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIA
QPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM
HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHF
TCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;TLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIA
IIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIA
QPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM
HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHF
TCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
C ? 
4 'polypeptide(L)' no no SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFRE 
SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFRE G ? 
5 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSSDIVMTQATSSVPVTPGESVSISC
RSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTF
GAGTKLEL
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSSDIVMTQATSSVPVTPGESVSISC
RSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTF
GAGTKLEL
;
S ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        '(4aR,5aR)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid' 
_pdbx_entity_nonpoly.comp_id     XOT 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   HIS n 
1 3   PHE n 
1 4   LEU n 
1 5   GLU n 
1 6   ILE n 
1 7   ASP n 
1 8   LYS n 
1 9   LYS n 
1 10  ASN n 
1 11  CYS n 
1 12  CYS n 
1 13  VAL n 
1 14  PHE n 
1 15  ARG n 
1 16  ASP n 
1 17  ASP n 
1 18  PHE n 
1 19  ILE n 
1 20  VAL n 
1 21  LYS n 
1 22  VAL n 
1 23  LEU n 
1 24  PRO n 
1 25  PRO n 
1 26  VAL n 
1 27  LEU n 
1 28  GLY n 
1 29  LEU n 
1 30  GLU n 
1 31  PHE n 
1 32  ILE n 
1 33  PHE n 
1 34  GLY n 
1 35  LEU n 
1 36  LEU n 
1 37  GLY n 
1 38  ASN n 
1 39  GLY n 
1 40  LEU n 
1 41  ALA n 
1 42  LEU n 
1 43  TRP n 
1 44  ILE n 
1 45  PHE n 
1 46  CYS n 
1 47  PHE n 
1 48  HIS n 
1 49  LEU n 
1 50  LYS n 
1 51  SER n 
1 52  TRP n 
1 53  LYS n 
1 54  SER n 
1 55  SER n 
1 56  ARG n 
1 57  ILE n 
1 58  PHE n 
1 59  LEU n 
1 60  PHE n 
1 61  ASN n 
1 62  LEU n 
1 63  ALA n 
1 64  VAL n 
1 65  ALA n 
1 66  ASP n 
1 67  PHE n 
1 68  LEU n 
1 69  LEU n 
1 70  ILE n 
1 71  ILE n 
1 72  CYS n 
1 73  LEU n 
1 74  PRO n 
1 75  PHE n 
1 76  LEU n 
1 77  MET n 
1 78  ASP n 
1 79  ASN n 
1 80  TYR n 
1 81  VAL n 
1 82  ARG n 
1 83  ARG n 
1 84  TRP n 
1 85  ASP n 
1 86  TRP n 
1 87  LYS n 
1 88  PHE n 
1 89  GLY n 
1 90  ASP n 
1 91  ILE n 
1 92  PRO n 
1 93  CYS n 
1 94  ARG n 
1 95  LEU n 
1 96  MET n 
1 97  LEU n 
1 98  PHE n 
1 99  MET n 
1 100 LEU n 
1 101 ALA n 
1 102 MET n 
1 103 ASN n 
1 104 ARG n 
1 105 GLN n 
1 106 GLY n 
1 107 SER n 
1 108 ILE n 
1 109 ILE n 
1 110 PHE n 
1 111 LEU n 
1 112 THR n 
1 113 VAL n 
1 114 VAL n 
1 115 ALA n 
1 116 VAL n 
1 117 ASP n 
1 118 ARG n 
1 119 TYR n 
1 120 PHE n 
1 121 ARG n 
1 122 VAL n 
1 123 VAL n 
1 124 HIS n 
1 125 PRO n 
1 126 HIS n 
1 127 HIS n 
1 128 ALA n 
1 129 LEU n 
1 130 ASN n 
1 131 LYS n 
1 132 ILE n 
1 133 SER n 
1 134 ASN n 
1 135 ARG n 
1 136 THR n 
1 137 ALA n 
1 138 ALA n 
1 139 ILE n 
1 140 ILE n 
1 141 SER n 
1 142 CYS n 
1 143 LEU n 
1 144 LEU n 
1 145 TRP n 
1 146 GLY n 
1 147 ILE n 
1 148 THR n 
1 149 ILE n 
1 150 GLY n 
1 151 LEU n 
1 152 THR n 
1 153 VAL n 
1 154 HIS n 
1 155 LEU n 
1 156 LEU n 
1 157 LYS n 
1 158 LYS n 
1 159 LYS n 
1 160 MET n 
1 161 PRO n 
1 162 ILE n 
1 163 GLN n 
1 164 ASN n 
1 165 GLY n 
1 166 GLY n 
1 167 ALA n 
1 168 ASN n 
1 169 LEU n 
1 170 CYS n 
1 171 SER n 
1 172 SER n 
1 173 PHE n 
1 174 SER n 
1 175 ILE n 
1 176 CYS n 
1 177 HIS n 
1 178 THR n 
1 179 PHE n 
1 180 GLN n 
1 181 TRP n 
1 182 HIS n 
1 183 GLU n 
1 184 ALA n 
1 185 MET n 
1 186 PHE n 
1 187 LEU n 
1 188 LEU n 
1 189 GLU n 
1 190 PHE n 
1 191 PHE n 
1 192 LEU n 
1 193 PRO n 
1 194 LEU n 
1 195 GLY n 
1 196 ILE n 
1 197 ILE n 
1 198 LEU n 
1 199 PHE n 
1 200 CYS n 
1 201 SER n 
1 202 ALA n 
1 203 ARG n 
1 204 ILE n 
1 205 ILE n 
1 206 TRP n 
1 207 SER n 
1 208 LEU n 
1 209 ARG n 
1 210 GLN n 
1 211 ARG n 
1 212 GLN n 
1 213 MET n 
1 214 ASP n 
1 215 ARG n 
1 216 HIS n 
1 217 ALA n 
1 218 LYS n 
1 219 ILE n 
1 220 LYS n 
1 221 ARG n 
1 222 ALA n 
1 223 ILE n 
1 224 THR n 
1 225 PHE n 
1 226 ILE n 
1 227 MET n 
1 228 VAL n 
1 229 VAL n 
1 230 ALA n 
1 231 ILE n 
1 232 VAL n 
1 233 PHE n 
1 234 VAL n 
1 235 ILE n 
1 236 CYS n 
1 237 PHE n 
1 238 LEU n 
1 239 PRO n 
1 240 SER n 
1 241 VAL n 
1 242 VAL n 
1 243 VAL n 
1 244 ARG n 
1 245 ILE n 
1 246 ARG n 
1 247 ILE n 
1 248 PHE n 
1 249 TRP n 
1 250 LEU n 
1 251 LEU n 
1 252 HIS n 
1 253 THR n 
1 254 SER n 
1 255 GLY n 
1 256 THR n 
1 257 GLN n 
1 258 ASN n 
1 259 CYS n 
1 260 GLU n 
1 261 VAL n 
1 262 TYR n 
1 263 ARG n 
1 264 SER n 
1 265 VAL n 
1 266 ASP n 
1 267 LEU n 
1 268 ALA n 
1 269 PHE n 
1 270 PHE n 
1 271 ILE n 
1 272 THR n 
1 273 LEU n 
1 274 SER n 
1 275 PHE n 
1 276 THR n 
1 277 TYR n 
1 278 MET n 
1 279 ASN n 
1 280 SER n 
1 281 MET n 
1 282 LEU n 
1 283 ASP n 
1 284 PRO n 
1 285 VAL n 
1 286 VAL n 
1 287 TYR n 
1 288 TYR n 
1 289 PHE n 
1 290 SER n 
1 291 SER n 
1 292 PRO n 
1 293 SER n 
1 294 PHE n 
2 1   LEU n 
2 2   ASP n 
2 3   GLN n 
2 4   LEU n 
2 5   ARG n 
2 6   GLN n 
2 7   GLU n 
2 8   ALA n 
2 9   GLU n 
2 10  GLN n 
2 11  LEU n 
2 12  LYS n 
2 13  ASN n 
2 14  GLN n 
2 15  ILE n 
2 16  ARG n 
2 17  ASP n 
2 18  ALA n 
2 19  ARG n 
2 20  LYS n 
2 21  ALA n 
2 22  CYS n 
2 23  ALA n 
2 24  ASP n 
2 25  ALA n 
2 26  THR n 
2 27  LEU n 
2 28  SER n 
2 29  GLN n 
2 30  ILE n 
2 31  THR n 
2 32  ASN n 
2 33  ASN n 
2 34  ILE n 
2 35  ASP n 
2 36  PRO n 
2 37  VAL n 
2 38  GLY n 
2 39  ARG n 
2 40  ILE n 
2 41  GLN n 
2 42  MET n 
2 43  ARG n 
2 44  THR n 
2 45  ARG n 
2 46  ARG n 
2 47  THR n 
2 48  LEU n 
2 49  ARG n 
2 50  GLY n 
2 51  HIS n 
2 52  LEU n 
2 53  ALA n 
2 54  LYS n 
2 55  ILE n 
2 56  TYR n 
2 57  ALA n 
2 58  MET n 
2 59  HIS n 
2 60  TRP n 
2 61  GLY n 
2 62  THR n 
2 63  ASP n 
2 64  SER n 
2 65  ARG n 
2 66  LEU n 
2 67  LEU n 
2 68  VAL n 
2 69  SER n 
2 70  ALA n 
2 71  SER n 
2 72  GLN n 
2 73  ASP n 
2 74  GLY n 
2 75  LYS n 
2 76  LEU n 
2 77  ILE n 
2 78  ILE n 
2 79  TRP n 
2 80  ASP n 
2 81  SER n 
2 82  TYR n 
2 83  THR n 
2 84  THR n 
2 85  ASN n 
2 86  LYS n 
2 87  VAL n 
2 88  HIS n 
2 89  ALA n 
2 90  ILE n 
2 91  PRO n 
2 92  LEU n 
2 93  ARG n 
2 94  SER n 
2 95  SER n 
2 96  TRP n 
2 97  VAL n 
2 98  MET n 
2 99  THR n 
2 100 CYS n 
2 101 ALA n 
2 102 TYR n 
2 103 ALA n 
2 104 PRO n 
2 105 SER n 
2 106 GLY n 
2 107 ASN n 
2 108 TYR n 
2 109 VAL n 
2 110 ALA n 
2 111 CYS n 
2 112 GLY n 
2 113 GLY n 
2 114 LEU n 
2 115 ASP n 
2 116 ASN n 
2 117 ILE n 
2 118 CYS n 
2 119 SER n 
2 120 ILE n 
2 121 TYR n 
2 122 ASN n 
2 123 LEU n 
2 124 LYS n 
2 125 THR n 
2 126 ARG n 
2 127 GLU n 
2 128 GLY n 
2 129 ASN n 
2 130 VAL n 
2 131 ARG n 
2 132 VAL n 
2 133 SER n 
2 134 ARG n 
2 135 GLU n 
2 136 LEU n 
2 137 ALA n 
2 138 GLY n 
2 139 HIS n 
2 140 THR n 
2 141 GLY n 
2 142 TYR n 
2 143 LEU n 
2 144 SER n 
2 145 CYS n 
2 146 CYS n 
2 147 ARG n 
2 148 PHE n 
2 149 LEU n 
2 150 ASP n 
2 151 ASP n 
2 152 ASN n 
2 153 GLN n 
2 154 ILE n 
2 155 VAL n 
2 156 THR n 
2 157 SER n 
2 158 SER n 
2 159 GLY n 
2 160 ASP n 
2 161 THR n 
2 162 THR n 
2 163 CYS n 
2 164 ALA n 
2 165 LEU n 
2 166 TRP n 
2 167 ASP n 
2 168 ILE n 
2 169 GLU n 
2 170 THR n 
2 171 GLY n 
2 172 GLN n 
2 173 GLN n 
2 174 THR n 
2 175 THR n 
2 176 THR n 
2 177 PHE n 
2 178 THR n 
2 179 GLY n 
2 180 HIS n 
2 181 THR n 
2 182 GLY n 
2 183 ASP n 
2 184 VAL n 
2 185 MET n 
2 186 SER n 
2 187 LEU n 
2 188 SER n 
2 189 LEU n 
2 190 ALA n 
2 191 PRO n 
2 192 ASP n 
2 193 THR n 
2 194 ARG n 
2 195 LEU n 
2 196 PHE n 
2 197 VAL n 
2 198 SER n 
2 199 GLY n 
2 200 ALA n 
2 201 CYS n 
2 202 ASP n 
2 203 ALA n 
2 204 SER n 
2 205 ALA n 
2 206 LYS n 
2 207 LEU n 
2 208 TRP n 
2 209 ASP n 
2 210 VAL n 
2 211 ARG n 
2 212 GLU n 
2 213 GLY n 
2 214 MET n 
2 215 CYS n 
2 216 ARG n 
2 217 GLN n 
2 218 THR n 
2 219 PHE n 
2 220 THR n 
2 221 GLY n 
2 222 HIS n 
2 223 GLU n 
2 224 SER n 
2 225 ASP n 
2 226 ILE n 
2 227 ASN n 
2 228 ALA n 
2 229 ILE n 
2 230 CYS n 
2 231 PHE n 
2 232 PHE n 
2 233 PRO n 
2 234 ASN n 
2 235 GLY n 
2 236 ASN n 
2 237 ALA n 
2 238 PHE n 
2 239 ALA n 
2 240 THR n 
2 241 GLY n 
2 242 SER n 
2 243 ASP n 
2 244 ASP n 
2 245 ALA n 
2 246 THR n 
2 247 CYS n 
2 248 ARG n 
2 249 LEU n 
2 250 PHE n 
2 251 ASP n 
2 252 LEU n 
2 253 ARG n 
2 254 ALA n 
2 255 ASP n 
2 256 GLN n 
2 257 GLU n 
2 258 LEU n 
2 259 MET n 
2 260 THR n 
2 261 TYR n 
2 262 SER n 
2 263 HIS n 
2 264 ASP n 
2 265 ASN n 
2 266 ILE n 
2 267 ILE n 
2 268 CYS n 
2 269 GLY n 
2 270 ILE n 
2 271 THR n 
2 272 SER n 
2 273 VAL n 
2 274 SER n 
2 275 PHE n 
2 276 SER n 
2 277 LYS n 
2 278 SER n 
2 279 GLY n 
2 280 ARG n 
2 281 LEU n 
2 282 LEU n 
2 283 LEU n 
2 284 ALA n 
2 285 GLY n 
2 286 TYR n 
2 287 ASP n 
2 288 ASP n 
2 289 PHE n 
2 290 ASN n 
2 291 CYS n 
2 292 ASN n 
2 293 VAL n 
2 294 TRP n 
2 295 ASP n 
2 296 ALA n 
2 297 LEU n 
2 298 LYS n 
2 299 ALA n 
2 300 ASP n 
2 301 ARG n 
2 302 ALA n 
2 303 GLY n 
2 304 VAL n 
2 305 LEU n 
2 306 ALA n 
2 307 GLY n 
2 308 HIS n 
2 309 ASP n 
2 310 ASN n 
2 311 ARG n 
2 312 VAL n 
2 313 SER n 
2 314 CYS n 
2 315 LEU n 
2 316 GLY n 
2 317 VAL n 
2 318 THR n 
2 319 ASP n 
2 320 ASP n 
2 321 GLY n 
2 322 MET n 
2 323 ALA n 
2 324 VAL n 
2 325 ALA n 
2 326 THR n 
2 327 GLY n 
2 328 SER n 
2 329 TRP n 
2 330 ASP n 
2 331 SER n 
2 332 PHE n 
2 333 LEU n 
2 334 LYS n 
2 335 ILE n 
2 336 TRP n 
2 337 ASN n 
3 1   THR n 
3 2   LEU n 
3 3   SER n 
3 4   ALA n 
3 5   GLU n 
3 6   ASP n 
3 7   LYS n 
3 8   ALA n 
3 9   ALA n 
3 10  VAL n 
3 11  GLU n 
3 12  ARG n 
3 13  SER n 
3 14  LYS n 
3 15  MET n 
3 16  ILE n 
3 17  ASP n 
3 18  ARG n 
3 19  ASN n 
3 20  LEU n 
3 21  ARG n 
3 22  GLU n 
3 23  ASP n 
3 24  GLY n 
3 25  GLU n 
3 26  LYS n 
3 27  ALA n 
3 28  ALA n 
3 29  ARG n 
3 30  GLU n 
3 31  VAL n 
3 32  LYS n 
3 33  LEU n 
3 34  LEU n 
3 35  LEU n 
3 36  LEU n 
3 37  GLY n 
3 38  ALA n 
3 39  GLY n 
3 40  GLU n 
3 41  SER n 
3 42  GLY n 
3 43  LYS n 
3 44  SER n 
3 45  THR n 
3 46  ILE n 
3 47  VAL n 
3 48  LYS n 
3 49  GLN n 
3 50  MET n 
3 51  LYS n 
3 52  ILE n 
3 53  ILE n 
3 54  HIS n 
3 55  GLU n 
3 56  ALA n 
3 57  GLY n 
3 58  TYR n 
3 59  SER n 
3 60  GLU n 
3 61  GLU n 
3 62  GLU n 
3 63  CYS n 
3 64  LYS n 
3 65  GLN n 
3 66  TYR n 
3 67  LYS n 
3 68  ALA n 
3 69  VAL n 
3 70  VAL n 
3 71  TYR n 
3 72  SER n 
3 73  ASN n 
3 74  THR n 
3 75  ILE n 
3 76  GLN n 
3 77  SER n 
3 78  ILE n 
3 79  ILE n 
3 80  ALA n 
3 81  ILE n 
3 82  ILE n 
3 83  ARG n 
3 84  ALA n 
3 85  MET n 
3 86  GLY n 
3 87  ARG n 
3 88  LEU n 
3 89  LYS n 
3 90  ILE n 
3 91  ASP n 
3 92  PHE n 
3 93  GLY n 
3 94  ASP n 
3 95  SER n 
3 96  ALA n 
3 97  ARG n 
3 98  ALA n 
3 99  ASP n 
3 100 ASP n 
3 101 ALA n 
3 102 ARG n 
3 103 GLN n 
3 104 LEU n 
3 105 PHE n 
3 106 VAL n 
3 107 LEU n 
3 108 ALA n 
3 109 GLY n 
3 110 ALA n 
3 111 ALA n 
3 112 GLU n 
3 113 GLU n 
3 114 GLY n 
3 115 PHE n 
3 116 MET n 
3 117 THR n 
3 118 ALA n 
3 119 GLU n 
3 120 LEU n 
3 121 ALA n 
3 122 GLY n 
3 123 VAL n 
3 124 ILE n 
3 125 LYS n 
3 126 ARG n 
3 127 LEU n 
3 128 TRP n 
3 129 LYS n 
3 130 ASP n 
3 131 SER n 
3 132 GLY n 
3 133 VAL n 
3 134 GLN n 
3 135 ALA n 
3 136 CYS n 
3 137 PHE n 
3 138 ASN n 
3 139 ARG n 
3 140 SER n 
3 141 ARG n 
3 142 GLU n 
3 143 TYR n 
3 144 GLN n 
3 145 LEU n 
3 146 ASN n 
3 147 ASP n 
3 148 SER n 
3 149 ALA n 
3 150 ALA n 
3 151 TYR n 
3 152 TYR n 
3 153 LEU n 
3 154 ASN n 
3 155 ASP n 
3 156 LEU n 
3 157 ASP n 
3 158 ARG n 
3 159 ILE n 
3 160 ALA n 
3 161 GLN n 
3 162 PRO n 
3 163 ASN n 
3 164 TYR n 
3 165 ILE n 
3 166 PRO n 
3 167 THR n 
3 168 GLN n 
3 169 GLN n 
3 170 ASP n 
3 171 VAL n 
3 172 LEU n 
3 173 ARG n 
3 174 THR n 
3 175 ARG n 
3 176 VAL n 
3 177 LYS n 
3 178 THR n 
3 179 THR n 
3 180 GLY n 
3 181 ILE n 
3 182 VAL n 
3 183 GLU n 
3 184 THR n 
3 185 HIS n 
3 186 PHE n 
3 187 THR n 
3 188 PHE n 
3 189 LYS n 
3 190 ASP n 
3 191 LEU n 
3 192 HIS n 
3 193 PHE n 
3 194 LYS n 
3 195 MET n 
3 196 PHE n 
3 197 ASP n 
3 198 VAL n 
3 199 GLY n 
3 200 ALA n 
3 201 GLN n 
3 202 ARG n 
3 203 SER n 
3 204 GLU n 
3 205 ARG n 
3 206 LYS n 
3 207 LYS n 
3 208 TRP n 
3 209 ILE n 
3 210 HIS n 
3 211 CYS n 
3 212 PHE n 
3 213 GLU n 
3 214 GLY n 
3 215 VAL n 
3 216 THR n 
3 217 ALA n 
3 218 ILE n 
3 219 ILE n 
3 220 PHE n 
3 221 CYS n 
3 222 VAL n 
3 223 ALA n 
3 224 LEU n 
3 225 SER n 
3 226 ASP n 
3 227 TYR n 
3 228 ASP n 
3 229 LEU n 
3 230 VAL n 
3 231 LEU n 
3 232 ALA n 
3 233 GLU n 
3 234 ASP n 
3 235 GLU n 
3 236 GLU n 
3 237 MET n 
3 238 ASN n 
3 239 ARG n 
3 240 MET n 
3 241 HIS n 
3 242 GLU n 
3 243 SER n 
3 244 MET n 
3 245 LYS n 
3 246 LEU n 
3 247 PHE n 
3 248 ASP n 
3 249 SER n 
3 250 ILE n 
3 251 CYS n 
3 252 ASN n 
3 253 ASN n 
3 254 LYS n 
3 255 TRP n 
3 256 PHE n 
3 257 THR n 
3 258 ASP n 
3 259 THR n 
3 260 SER n 
3 261 ILE n 
3 262 ILE n 
3 263 LEU n 
3 264 PHE n 
3 265 LEU n 
3 266 ASN n 
3 267 LYS n 
3 268 LYS n 
3 269 ASP n 
3 270 LEU n 
3 271 PHE n 
3 272 GLU n 
3 273 GLU n 
3 274 LYS n 
3 275 ILE n 
3 276 LYS n 
3 277 LYS n 
3 278 SER n 
3 279 PRO n 
3 280 LEU n 
3 281 THR n 
3 282 ILE n 
3 283 CYS n 
3 284 TYR n 
3 285 PRO n 
3 286 GLU n 
3 287 TYR n 
3 288 ALA n 
3 289 GLY n 
3 290 SER n 
3 291 ASN n 
3 292 THR n 
3 293 TYR n 
3 294 GLU n 
3 295 GLU n 
3 296 ALA n 
3 297 ALA n 
3 298 ALA n 
3 299 TYR n 
3 300 ILE n 
3 301 GLN n 
3 302 CYS n 
3 303 GLN n 
3 304 PHE n 
3 305 GLU n 
3 306 ASP n 
3 307 LEU n 
3 308 ASN n 
3 309 LYS n 
3 310 ARG n 
3 311 LYS n 
3 312 ASP n 
3 313 THR n 
3 314 LYS n 
3 315 GLU n 
3 316 ILE n 
3 317 TYR n 
3 318 THR n 
3 319 HIS n 
3 320 PHE n 
3 321 THR n 
3 322 CYS n 
3 323 SER n 
3 324 THR n 
3 325 ASP n 
3 326 THR n 
3 327 LYS n 
3 328 ASN n 
3 329 VAL n 
3 330 GLN n 
3 331 PHE n 
3 332 VAL n 
3 333 PHE n 
3 334 ASP n 
3 335 ALA n 
3 336 VAL n 
3 337 THR n 
3 338 ASP n 
3 339 VAL n 
3 340 ILE n 
3 341 ILE n 
3 342 LYS n 
3 343 ASN n 
3 344 ASN n 
3 345 LEU n 
3 346 LYS n 
3 347 ASP n 
3 348 CYS n 
3 349 GLY n 
3 350 LEU n 
3 351 PHE n 
4 1   SER n 
4 2   ILE n 
4 3   ALA n 
4 4   GLN n 
4 5   ALA n 
4 6   ARG n 
4 7   LYS n 
4 8   LEU n 
4 9   VAL n 
4 10  GLU n 
4 11  GLN n 
4 12  LEU n 
4 13  LYS n 
4 14  MET n 
4 15  GLU n 
4 16  ALA n 
4 17  ASN n 
4 18  ILE n 
4 19  ASP n 
4 20  ARG n 
4 21  ILE n 
4 22  LYS n 
4 23  VAL n 
4 24  SER n 
4 25  LYS n 
4 26  ALA n 
4 27  ALA n 
4 28  ALA n 
4 29  ASP n 
4 30  LEU n 
4 31  MET n 
4 32  ALA n 
4 33  TYR n 
4 34  CYS n 
4 35  GLU n 
4 36  ALA n 
4 37  HIS n 
4 38  ALA n 
4 39  LYS n 
4 40  GLU n 
4 41  ASP n 
4 42  PRO n 
4 43  LEU n 
4 44  LEU n 
4 45  THR n 
4 46  PRO n 
4 47  VAL n 
4 48  PRO n 
4 49  ALA n 
4 50  SER n 
4 51  GLU n 
4 52  ASN n 
4 53  PRO n 
4 54  PHE n 
4 55  ARG n 
4 56  GLU n 
5 1   ASP n 
5 2   VAL n 
5 3   GLN n 
5 4   LEU n 
5 5   VAL n 
5 6   GLU n 
5 7   SER n 
5 8   GLY n 
5 9   GLY n 
5 10  GLY n 
5 11  LEU n 
5 12  VAL n 
5 13  GLN n 
5 14  PRO n 
5 15  GLY n 
5 16  GLY n 
5 17  SER n 
5 18  ARG n 
5 19  LYS n 
5 20  LEU n 
5 21  SER n 
5 22  CYS n 
5 23  SER n 
5 24  ALA n 
5 25  SER n 
5 26  GLY n 
5 27  PHE n 
5 28  ALA n 
5 29  PHE n 
5 30  SER n 
5 31  SER n 
5 32  PHE n 
5 33  GLY n 
5 34  MET n 
5 35  HIS n 
5 36  TRP n 
5 37  VAL n 
5 38  ARG n 
5 39  GLN n 
5 40  ALA n 
5 41  PRO n 
5 42  GLU n 
5 43  LYS n 
5 44  GLY n 
5 45  LEU n 
5 46  GLU n 
5 47  TRP n 
5 48  VAL n 
5 49  ALA n 
5 50  TYR n 
5 51  ILE n 
5 52  SER n 
5 53  SER n 
5 54  GLY n 
5 55  SER n 
5 56  GLY n 
5 57  THR n 
5 58  ILE n 
5 59  TYR n 
5 60  TYR n 
5 61  ALA n 
5 62  ASP n 
5 63  THR n 
5 64  VAL n 
5 65  LYS n 
5 66  GLY n 
5 67  ARG n 
5 68  PHE n 
5 69  THR n 
5 70  ILE n 
5 71  SER n 
5 72  ARG n 
5 73  ASP n 
5 74  ASP n 
5 75  PRO n 
5 76  LYS n 
5 77  ASN n 
5 78  THR n 
5 79  LEU n 
5 80  PHE n 
5 81  LEU n 
5 82  GLN n 
5 83  MET n 
5 84  THR n 
5 85  SER n 
5 86  LEU n 
5 87  ARG n 
5 88  SER n 
5 89  GLU n 
5 90  ASP n 
5 91  THR n 
5 92  ALA n 
5 93  MET n 
5 94  TYR n 
5 95  TYR n 
5 96  CYS n 
5 97  VAL n 
5 98  ARG n 
5 99  SER n 
5 100 ILE n 
5 101 TYR n 
5 102 TYR n 
5 103 TYR n 
5 104 GLY n 
5 105 SER n 
5 106 SER n 
5 107 PRO n 
5 108 PHE n 
5 109 ASP n 
5 110 PHE n 
5 111 TRP n 
5 112 GLY n 
5 113 GLN n 
5 114 GLY n 
5 115 THR n 
5 116 THR n 
5 117 LEU n 
5 118 THR n 
5 119 VAL n 
5 120 SER n 
5 121 SER n 
5 122 GLY n 
5 123 GLY n 
5 124 GLY n 
5 125 GLY n 
5 126 SER n 
5 127 GLY n 
5 128 GLY n 
5 129 GLY n 
5 130 GLY n 
5 131 SER n 
5 132 GLY n 
5 133 GLY n 
5 134 GLY n 
5 135 GLY n 
5 136 SER n 
5 137 SER n 
5 138 ASP n 
5 139 ILE n 
5 140 VAL n 
5 141 MET n 
5 142 THR n 
5 143 GLN n 
5 144 ALA n 
5 145 THR n 
5 146 SER n 
5 147 SER n 
5 148 VAL n 
5 149 PRO n 
5 150 VAL n 
5 151 THR n 
5 152 PRO n 
5 153 GLY n 
5 154 GLU n 
5 155 SER n 
5 156 VAL n 
5 157 SER n 
5 158 ILE n 
5 159 SER n 
5 160 CYS n 
5 161 ARG n 
5 162 SER n 
5 163 SER n 
5 164 LYS n 
5 165 SER n 
5 166 LEU n 
5 167 LEU n 
5 168 HIS n 
5 169 SER n 
5 170 ASN n 
5 171 GLY n 
5 172 ASN n 
5 173 THR n 
5 174 TYR n 
5 175 LEU n 
5 176 TYR n 
5 177 TRP n 
5 178 PHE n 
5 179 LEU n 
5 180 GLN n 
5 181 ARG n 
5 182 PRO n 
5 183 GLY n 
5 184 GLN n 
5 185 SER n 
5 186 PRO n 
5 187 GLN n 
5 188 LEU n 
5 189 LEU n 
5 190 ILE n 
5 191 TYR n 
5 192 ARG n 
5 193 MET n 
5 194 SER n 
5 195 ASN n 
5 196 LEU n 
5 197 ALA n 
5 198 SER n 
5 199 GLY n 
5 200 VAL n 
5 201 PRO n 
5 202 ASP n 
5 203 ARG n 
5 204 PHE n 
5 205 SER n 
5 206 GLY n 
5 207 SER n 
5 208 GLY n 
5 209 SER n 
5 210 GLY n 
5 211 THR n 
5 212 ALA n 
5 213 PHE n 
5 214 THR n 
5 215 LEU n 
5 216 THR n 
5 217 ILE n 
5 218 SER n 
5 219 ARG n 
5 220 LEU n 
5 221 GLU n 
5 222 ALA n 
5 223 GLU n 
5 224 ASP n 
5 225 VAL n 
5 226 GLY n 
5 227 VAL n 
5 228 TYR n 
5 229 TYR n 
5 230 CYS n 
5 231 MET n 
5 232 GLN n 
5 233 HIS n 
5 234 LEU n 
5 235 GLU n 
5 236 TYR n 
5 237 PRO n 
5 238 LEU n 
5 239 THR n 
5 240 PHE n 
5 241 GLY n 
5 242 ALA n 
5 243 GLY n 
5 244 THR n 
5 245 LYS n 
5 246 LEU n 
5 247 GLU n 
5 248 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 294 human ? 'HCAR2, GPR109A, HCA2, HM74A, NIACR1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 337 human ? GNB1                                  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 351 human ? GNAI1                                 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 56  human ? GNG2                                  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 248 human ? ?                                     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 
? 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                                        ?         
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                                                                       ?         
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                                     ?         
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                                ?         
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                                                                       ?         
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                                      ?         
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                                ?         
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                                                                        ?         
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                                      ?         
'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                                                                     ?         
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                                                                        ?         
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                                                         ?         
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                                                     ?         
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                                                                  ?         
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                                                                        ?         
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                                                                         ?         
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                                                                      ?         
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                                     ?         
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                                                       ?         
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                                                         ?         
'C5 H11 N O2'    117.146 
XOT non-polymer         . '(4aR,5aR)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid' 'MK 1903' 
'C8 H8 N2 O2'    164.161 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   8   8   ASP ASP A . n 
A 1 2   HIS 2   9   9   HIS HIS A . n 
A 1 3   PHE 3   10  10  PHE PHE A . n 
A 1 4   LEU 4   11  11  LEU LEU A . n 
A 1 5   GLU 5   12  12  GLU GLU A . n 
A 1 6   ILE 6   13  13  ILE ILE A . n 
A 1 7   ASP 7   14  14  ASP ASP A . n 
A 1 8   LYS 8   15  15  LYS LYS A . n 
A 1 9   LYS 9   16  16  LYS LYS A . n 
A 1 10  ASN 10  17  17  ASN ASN A . n 
A 1 11  CYS 11  18  18  CYS CYS A . n 
A 1 12  CYS 12  19  19  CYS CYS A . n 
A 1 13  VAL 13  20  20  VAL VAL A . n 
A 1 14  PHE 14  21  21  PHE PHE A . n 
A 1 15  ARG 15  22  22  ARG ARG A . n 
A 1 16  ASP 16  23  23  ASP ASP A . n 
A 1 17  ASP 17  24  24  ASP ASP A . n 
A 1 18  PHE 18  25  25  PHE PHE A . n 
A 1 19  ILE 19  26  26  ILE ILE A . n 
A 1 20  VAL 20  27  27  VAL VAL A . n 
A 1 21  LYS 21  28  28  LYS LYS A . n 
A 1 22  VAL 22  29  29  VAL VAL A . n 
A 1 23  LEU 23  30  30  LEU LEU A . n 
A 1 24  PRO 24  31  31  PRO PRO A . n 
A 1 25  PRO 25  32  32  PRO PRO A . n 
A 1 26  VAL 26  33  33  VAL VAL A . n 
A 1 27  LEU 27  34  34  LEU LEU A . n 
A 1 28  GLY 28  35  35  GLY GLY A . n 
A 1 29  LEU 29  36  36  LEU LEU A . n 
A 1 30  GLU 30  37  37  GLU GLU A . n 
A 1 31  PHE 31  38  38  PHE PHE A . n 
A 1 32  ILE 32  39  39  ILE ILE A . n 
A 1 33  PHE 33  40  40  PHE PHE A . n 
A 1 34  GLY 34  41  41  GLY GLY A . n 
A 1 35  LEU 35  42  42  LEU LEU A . n 
A 1 36  LEU 36  43  43  LEU LEU A . n 
A 1 37  GLY 37  44  44  GLY GLY A . n 
A 1 38  ASN 38  45  45  ASN ASN A . n 
A 1 39  GLY 39  46  46  GLY GLY A . n 
A 1 40  LEU 40  47  47  LEU LEU A . n 
A 1 41  ALA 41  48  48  ALA ALA A . n 
A 1 42  LEU 42  49  49  LEU LEU A . n 
A 1 43  TRP 43  50  50  TRP TRP A . n 
A 1 44  ILE 44  51  51  ILE ILE A . n 
A 1 45  PHE 45  52  52  PHE PHE A . n 
A 1 46  CYS 46  53  53  CYS CYS A . n 
A 1 47  PHE 47  54  54  PHE PHE A . n 
A 1 48  HIS 48  55  55  HIS HIS A . n 
A 1 49  LEU 49  56  56  LEU LEU A . n 
A 1 50  LYS 50  57  57  LYS LYS A . n 
A 1 51  SER 51  58  58  SER SER A . n 
A 1 52  TRP 52  59  59  TRP TRP A . n 
A 1 53  LYS 53  60  60  LYS LYS A . n 
A 1 54  SER 54  61  61  SER SER A . n 
A 1 55  SER 55  62  62  SER SER A . n 
A 1 56  ARG 56  63  63  ARG ARG A . n 
A 1 57  ILE 57  64  64  ILE ILE A . n 
A 1 58  PHE 58  65  65  PHE PHE A . n 
A 1 59  LEU 59  66  66  LEU LEU A . n 
A 1 60  PHE 60  67  67  PHE PHE A . n 
A 1 61  ASN 61  68  68  ASN ASN A . n 
A 1 62  LEU 62  69  69  LEU LEU A . n 
A 1 63  ALA 63  70  70  ALA ALA A . n 
A 1 64  VAL 64  71  71  VAL VAL A . n 
A 1 65  ALA 65  72  72  ALA ALA A . n 
A 1 66  ASP 66  73  73  ASP ASP A . n 
A 1 67  PHE 67  74  74  PHE PHE A . n 
A 1 68  LEU 68  75  75  LEU LEU A . n 
A 1 69  LEU 69  76  76  LEU LEU A . n 
A 1 70  ILE 70  77  77  ILE ILE A . n 
A 1 71  ILE 71  78  78  ILE ILE A . n 
A 1 72  CYS 72  79  79  CYS CYS A . n 
A 1 73  LEU 73  80  80  LEU LEU A . n 
A 1 74  PRO 74  81  81  PRO PRO A . n 
A 1 75  PHE 75  82  82  PHE PHE A . n 
A 1 76  LEU 76  83  83  LEU LEU A . n 
A 1 77  MET 77  84  84  MET MET A . n 
A 1 78  ASP 78  85  85  ASP ASP A . n 
A 1 79  ASN 79  86  86  ASN ASN A . n 
A 1 80  TYR 80  87  87  TYR TYR A . n 
A 1 81  VAL 81  88  88  VAL VAL A . n 
A 1 82  ARG 82  89  89  ARG ARG A . n 
A 1 83  ARG 83  90  90  ARG ARG A . n 
A 1 84  TRP 84  91  91  TRP TRP A . n 
A 1 85  ASP 85  92  92  ASP ASP A . n 
A 1 86  TRP 86  93  93  TRP TRP A . n 
A 1 87  LYS 87  94  94  LYS LYS A . n 
A 1 88  PHE 88  95  95  PHE PHE A . n 
A 1 89  GLY 89  96  96  GLY GLY A . n 
A 1 90  ASP 90  97  97  ASP ASP A . n 
A 1 91  ILE 91  98  98  ILE ILE A . n 
A 1 92  PRO 92  99  99  PRO PRO A . n 
A 1 93  CYS 93  100 100 CYS CYS A . n 
A 1 94  ARG 94  101 101 ARG ARG A . n 
A 1 95  LEU 95  102 102 LEU LEU A . n 
A 1 96  MET 96  103 103 MET MET A . n 
A 1 97  LEU 97  104 104 LEU LEU A . n 
A 1 98  PHE 98  105 105 PHE PHE A . n 
A 1 99  MET 99  106 106 MET MET A . n 
A 1 100 LEU 100 107 107 LEU LEU A . n 
A 1 101 ALA 101 108 108 ALA ALA A . n 
A 1 102 MET 102 109 109 MET MET A . n 
A 1 103 ASN 103 110 110 ASN ASN A . n 
A 1 104 ARG 104 111 111 ARG ARG A . n 
A 1 105 GLN 105 112 112 GLN GLN A . n 
A 1 106 GLY 106 113 113 GLY GLY A . n 
A 1 107 SER 107 114 114 SER SER A . n 
A 1 108 ILE 108 115 115 ILE ILE A . n 
A 1 109 ILE 109 116 116 ILE ILE A . n 
A 1 110 PHE 110 117 117 PHE PHE A . n 
A 1 111 LEU 111 118 118 LEU LEU A . n 
A 1 112 THR 112 119 119 THR THR A . n 
A 1 113 VAL 113 120 120 VAL VAL A . n 
A 1 114 VAL 114 121 121 VAL VAL A . n 
A 1 115 ALA 115 122 122 ALA ALA A . n 
A 1 116 VAL 116 123 123 VAL VAL A . n 
A 1 117 ASP 117 124 124 ASP ASP A . n 
A 1 118 ARG 118 125 125 ARG ARG A . n 
A 1 119 TYR 119 126 126 TYR TYR A . n 
A 1 120 PHE 120 127 127 PHE PHE A . n 
A 1 121 ARG 121 128 128 ARG ARG A . n 
A 1 122 VAL 122 129 129 VAL VAL A . n 
A 1 123 VAL 123 130 130 VAL VAL A . n 
A 1 124 HIS 124 131 131 HIS HIS A . n 
A 1 125 PRO 125 132 132 PRO PRO A . n 
A 1 126 HIS 126 133 133 HIS HIS A . n 
A 1 127 HIS 127 134 134 HIS HIS A . n 
A 1 128 ALA 128 135 135 ALA ALA A . n 
A 1 129 LEU 129 136 136 LEU LEU A . n 
A 1 130 ASN 130 137 137 ASN ASN A . n 
A 1 131 LYS 131 138 138 LYS LYS A . n 
A 1 132 ILE 132 139 139 ILE ILE A . n 
A 1 133 SER 133 140 140 SER SER A . n 
A 1 134 ASN 134 141 141 ASN ASN A . n 
A 1 135 ARG 135 142 142 ARG ARG A . n 
A 1 136 THR 136 143 143 THR THR A . n 
A 1 137 ALA 137 144 144 ALA ALA A . n 
A 1 138 ALA 138 145 145 ALA ALA A . n 
A 1 139 ILE 139 146 146 ILE ILE A . n 
A 1 140 ILE 140 147 147 ILE ILE A . n 
A 1 141 SER 141 148 148 SER SER A . n 
A 1 142 CYS 142 149 149 CYS CYS A . n 
A 1 143 LEU 143 150 150 LEU LEU A . n 
A 1 144 LEU 144 151 151 LEU LEU A . n 
A 1 145 TRP 145 152 152 TRP TRP A . n 
A 1 146 GLY 146 153 153 GLY GLY A . n 
A 1 147 ILE 147 154 154 ILE ILE A . n 
A 1 148 THR 148 155 155 THR THR A . n 
A 1 149 ILE 149 156 156 ILE ILE A . n 
A 1 150 GLY 150 157 157 GLY GLY A . n 
A 1 151 LEU 151 158 158 LEU LEU A . n 
A 1 152 THR 152 159 159 THR THR A . n 
A 1 153 VAL 153 160 160 VAL VAL A . n 
A 1 154 HIS 154 161 161 HIS HIS A . n 
A 1 155 LEU 155 162 162 LEU LEU A . n 
A 1 156 LEU 156 163 163 LEU LEU A . n 
A 1 157 LYS 157 164 164 LYS LYS A . n 
A 1 158 LYS 158 165 165 LYS LYS A . n 
A 1 159 LYS 159 166 166 LYS LYS A . n 
A 1 160 MET 160 167 167 MET MET A . n 
A 1 161 PRO 161 168 168 PRO PRO A . n 
A 1 162 ILE 162 169 169 ILE ILE A . n 
A 1 163 GLN 163 170 170 GLN GLN A . n 
A 1 164 ASN 164 171 171 ASN ASN A . n 
A 1 165 GLY 165 172 172 GLY GLY A . n 
A 1 166 GLY 166 173 173 GLY GLY A . n 
A 1 167 ALA 167 174 174 ALA ALA A . n 
A 1 168 ASN 168 175 175 ASN ASN A . n 
A 1 169 LEU 169 176 176 LEU LEU A . n 
A 1 170 CYS 170 177 177 CYS CYS A . n 
A 1 171 SER 171 178 178 SER SER A . n 
A 1 172 SER 172 179 179 SER SER A . n 
A 1 173 PHE 173 180 180 PHE PHE A . n 
A 1 174 SER 174 181 181 SER SER A . n 
A 1 175 ILE 175 182 182 ILE ILE A . n 
A 1 176 CYS 176 183 183 CYS CYS A . n 
A 1 177 HIS 177 184 184 HIS HIS A . n 
A 1 178 THR 178 185 185 THR THR A . n 
A 1 179 PHE 179 186 186 PHE PHE A . n 
A 1 180 GLN 180 187 187 GLN GLN A . n 
A 1 181 TRP 181 188 188 TRP TRP A . n 
A 1 182 HIS 182 189 189 HIS HIS A . n 
A 1 183 GLU 183 190 190 GLU GLU A . n 
A 1 184 ALA 184 191 191 ALA ALA A . n 
A 1 185 MET 185 192 192 MET MET A . n 
A 1 186 PHE 186 193 193 PHE PHE A . n 
A 1 187 LEU 187 194 194 LEU LEU A . n 
A 1 188 LEU 188 195 195 LEU LEU A . n 
A 1 189 GLU 189 196 196 GLU GLU A . n 
A 1 190 PHE 190 197 197 PHE PHE A . n 
A 1 191 PHE 191 198 198 PHE PHE A . n 
A 1 192 LEU 192 199 199 LEU LEU A . n 
A 1 193 PRO 193 200 200 PRO PRO A . n 
A 1 194 LEU 194 201 201 LEU LEU A . n 
A 1 195 GLY 195 202 202 GLY GLY A . n 
A 1 196 ILE 196 203 203 ILE ILE A . n 
A 1 197 ILE 197 204 204 ILE ILE A . n 
A 1 198 LEU 198 205 205 LEU LEU A . n 
A 1 199 PHE 199 206 206 PHE PHE A . n 
A 1 200 CYS 200 207 207 CYS CYS A . n 
A 1 201 SER 201 208 208 SER SER A . n 
A 1 202 ALA 202 209 209 ALA ALA A . n 
A 1 203 ARG 203 210 210 ARG ARG A . n 
A 1 204 ILE 204 211 211 ILE ILE A . n 
A 1 205 ILE 205 212 212 ILE ILE A . n 
A 1 206 TRP 206 213 213 TRP TRP A . n 
A 1 207 SER 207 214 214 SER SER A . n 
A 1 208 LEU 208 215 215 LEU LEU A . n 
A 1 209 ARG 209 216 216 ARG ARG A . n 
A 1 210 GLN 210 217 217 GLN GLN A . n 
A 1 211 ARG 211 218 218 ARG ARG A . n 
A 1 212 GLN 212 219 219 GLN GLN A . n 
A 1 213 MET 213 220 220 MET MET A . n 
A 1 214 ASP 214 221 221 ASP ASP A . n 
A 1 215 ARG 215 222 222 ARG ARG A . n 
A 1 216 HIS 216 223 223 HIS HIS A . n 
A 1 217 ALA 217 224 224 ALA ALA A . n 
A 1 218 LYS 218 225 225 LYS LYS A . n 
A 1 219 ILE 219 226 226 ILE ILE A . n 
A 1 220 LYS 220 227 227 LYS LYS A . n 
A 1 221 ARG 221 228 228 ARG ARG A . n 
A 1 222 ALA 222 229 229 ALA ALA A . n 
A 1 223 ILE 223 230 230 ILE ILE A . n 
A 1 224 THR 224 231 231 THR THR A . n 
A 1 225 PHE 225 232 232 PHE PHE A . n 
A 1 226 ILE 226 233 233 ILE ILE A . n 
A 1 227 MET 227 234 234 MET MET A . n 
A 1 228 VAL 228 235 235 VAL VAL A . n 
A 1 229 VAL 229 236 236 VAL VAL A . n 
A 1 230 ALA 230 237 237 ALA ALA A . n 
A 1 231 ILE 231 238 238 ILE ILE A . n 
A 1 232 VAL 232 239 239 VAL VAL A . n 
A 1 233 PHE 233 240 240 PHE PHE A . n 
A 1 234 VAL 234 241 241 VAL VAL A . n 
A 1 235 ILE 235 242 242 ILE ILE A . n 
A 1 236 CYS 236 243 243 CYS CYS A . n 
A 1 237 PHE 237 244 244 PHE PHE A . n 
A 1 238 LEU 238 245 245 LEU LEU A . n 
A 1 239 PRO 239 246 246 PRO PRO A . n 
A 1 240 SER 240 247 247 SER SER A . n 
A 1 241 VAL 241 248 248 VAL VAL A . n 
A 1 242 VAL 242 249 249 VAL VAL A . n 
A 1 243 VAL 243 250 250 VAL VAL A . n 
A 1 244 ARG 244 251 251 ARG ARG A . n 
A 1 245 ILE 245 252 252 ILE ILE A . n 
A 1 246 ARG 246 253 253 ARG ARG A . n 
A 1 247 ILE 247 254 254 ILE ILE A . n 
A 1 248 PHE 248 255 255 PHE PHE A . n 
A 1 249 TRP 249 256 256 TRP TRP A . n 
A 1 250 LEU 250 257 257 LEU LEU A . n 
A 1 251 LEU 251 258 258 LEU LEU A . n 
A 1 252 HIS 252 259 259 HIS HIS A . n 
A 1 253 THR 253 260 260 THR THR A . n 
A 1 254 SER 254 261 261 SER SER A . n 
A 1 255 GLY 255 262 262 GLY GLY A . n 
A 1 256 THR 256 263 263 THR THR A . n 
A 1 257 GLN 257 264 264 GLN GLN A . n 
A 1 258 ASN 258 265 265 ASN ASN A . n 
A 1 259 CYS 259 266 266 CYS CYS A . n 
A 1 260 GLU 260 267 267 GLU GLU A . n 
A 1 261 VAL 261 268 268 VAL VAL A . n 
A 1 262 TYR 262 269 269 TYR TYR A . n 
A 1 263 ARG 263 270 270 ARG ARG A . n 
A 1 264 SER 264 271 271 SER SER A . n 
A 1 265 VAL 265 272 272 VAL VAL A . n 
A 1 266 ASP 266 273 273 ASP ASP A . n 
A 1 267 LEU 267 274 274 LEU LEU A . n 
A 1 268 ALA 268 275 275 ALA ALA A . n 
A 1 269 PHE 269 276 276 PHE PHE A . n 
A 1 270 PHE 270 277 277 PHE PHE A . n 
A 1 271 ILE 271 278 278 ILE ILE A . n 
A 1 272 THR 272 279 279 THR THR A . n 
A 1 273 LEU 273 280 280 LEU LEU A . n 
A 1 274 SER 274 281 281 SER SER A . n 
A 1 275 PHE 275 282 282 PHE PHE A . n 
A 1 276 THR 276 283 283 THR THR A . n 
A 1 277 TYR 277 284 284 TYR TYR A . n 
A 1 278 MET 278 285 285 MET MET A . n 
A 1 279 ASN 279 286 286 ASN ASN A . n 
A 1 280 SER 280 287 287 SER SER A . n 
A 1 281 MET 281 288 288 MET MET A . n 
A 1 282 LEU 282 289 289 LEU LEU A . n 
A 1 283 ASP 283 290 290 ASP ASP A . n 
A 1 284 PRO 284 291 291 PRO PRO A . n 
A 1 285 VAL 285 292 292 VAL VAL A . n 
A 1 286 VAL 286 293 293 VAL VAL A . n 
A 1 287 TYR 287 294 294 TYR TYR A . n 
A 1 288 TYR 288 295 295 TYR TYR A . n 
A 1 289 PHE 289 296 296 PHE PHE A . n 
A 1 290 SER 290 297 297 SER SER A . n 
A 1 291 SER 291 298 298 SER SER A . n 
A 1 292 PRO 292 299 299 PRO PRO A . n 
A 1 293 SER 293 300 300 SER SER A . n 
A 1 294 PHE 294 301 301 PHE PHE A . n 
B 2 1   LEU 1   4   4   LEU LEU B . n 
B 2 2   ASP 2   5   5   ASP ASP B . n 
B 2 3   GLN 3   6   6   GLN GLN B . n 
B 2 4   LEU 4   7   7   LEU LEU B . n 
B 2 5   ARG 5   8   8   ARG ARG B . n 
B 2 6   GLN 6   9   9   GLN GLN B . n 
B 2 7   GLU 7   10  10  GLU GLU B . n 
B 2 8   ALA 8   11  11  ALA ALA B . n 
B 2 9   GLU 9   12  12  GLU GLU B . n 
B 2 10  GLN 10  13  13  GLN GLN B . n 
B 2 11  LEU 11  14  14  LEU LEU B . n 
B 2 12  LYS 12  15  15  LYS LYS B . n 
B 2 13  ASN 13  16  16  ASN ASN B . n 
B 2 14  GLN 14  17  17  GLN GLN B . n 
B 2 15  ILE 15  18  18  ILE ILE B . n 
B 2 16  ARG 16  19  19  ARG ARG B . n 
B 2 17  ASP 17  20  20  ASP ASP B . n 
B 2 18  ALA 18  21  21  ALA ALA B . n 
B 2 19  ARG 19  22  22  ARG ARG B . n 
B 2 20  LYS 20  23  23  LYS LYS B . n 
B 2 21  ALA 21  24  24  ALA ALA B . n 
B 2 22  CYS 22  25  25  CYS CYS B . n 
B 2 23  ALA 23  26  26  ALA ALA B . n 
B 2 24  ASP 24  27  27  ASP ASP B . n 
B 2 25  ALA 25  28  28  ALA ALA B . n 
B 2 26  THR 26  29  29  THR THR B . n 
B 2 27  LEU 27  30  30  LEU LEU B . n 
B 2 28  SER 28  31  31  SER SER B . n 
B 2 29  GLN 29  32  32  GLN GLN B . n 
B 2 30  ILE 30  33  33  ILE ILE B . n 
B 2 31  THR 31  34  34  THR THR B . n 
B 2 32  ASN 32  35  35  ASN ASN B . n 
B 2 33  ASN 33  36  36  ASN ASN B . n 
B 2 34  ILE 34  37  37  ILE ILE B . n 
B 2 35  ASP 35  38  38  ASP ASP B . n 
B 2 36  PRO 36  39  39  PRO PRO B . n 
B 2 37  VAL 37  40  40  VAL VAL B . n 
B 2 38  GLY 38  41  41  GLY GLY B . n 
B 2 39  ARG 39  42  42  ARG ARG B . n 
B 2 40  ILE 40  43  43  ILE ILE B . n 
B 2 41  GLN 41  44  44  GLN GLN B . n 
B 2 42  MET 42  45  45  MET MET B . n 
B 2 43  ARG 43  46  46  ARG ARG B . n 
B 2 44  THR 44  47  47  THR THR B . n 
B 2 45  ARG 45  48  48  ARG ARG B . n 
B 2 46  ARG 46  49  49  ARG ARG B . n 
B 2 47  THR 47  50  50  THR THR B . n 
B 2 48  LEU 48  51  51  LEU LEU B . n 
B 2 49  ARG 49  52  52  ARG ARG B . n 
B 2 50  GLY 50  53  53  GLY GLY B . n 
B 2 51  HIS 51  54  54  HIS HIS B . n 
B 2 52  LEU 52  55  55  LEU LEU B . n 
B 2 53  ALA 53  56  56  ALA ALA B . n 
B 2 54  LYS 54  57  57  LYS LYS B . n 
B 2 55  ILE 55  58  58  ILE ILE B . n 
B 2 56  TYR 56  59  59  TYR TYR B . n 
B 2 57  ALA 57  60  60  ALA ALA B . n 
B 2 58  MET 58  61  61  MET MET B . n 
B 2 59  HIS 59  62  62  HIS HIS B . n 
B 2 60  TRP 60  63  63  TRP TRP B . n 
B 2 61  GLY 61  64  64  GLY GLY B . n 
B 2 62  THR 62  65  65  THR THR B . n 
B 2 63  ASP 63  66  66  ASP ASP B . n 
B 2 64  SER 64  67  67  SER SER B . n 
B 2 65  ARG 65  68  68  ARG ARG B . n 
B 2 66  LEU 66  69  69  LEU LEU B . n 
B 2 67  LEU 67  70  70  LEU LEU B . n 
B 2 68  VAL 68  71  71  VAL VAL B . n 
B 2 69  SER 69  72  72  SER SER B . n 
B 2 70  ALA 70  73  73  ALA ALA B . n 
B 2 71  SER 71  74  74  SER SER B . n 
B 2 72  GLN 72  75  75  GLN GLN B . n 
B 2 73  ASP 73  76  76  ASP ASP B . n 
B 2 74  GLY 74  77  77  GLY GLY B . n 
B 2 75  LYS 75  78  78  LYS LYS B . n 
B 2 76  LEU 76  79  79  LEU LEU B . n 
B 2 77  ILE 77  80  80  ILE ILE B . n 
B 2 78  ILE 78  81  81  ILE ILE B . n 
B 2 79  TRP 79  82  82  TRP TRP B . n 
B 2 80  ASP 80  83  83  ASP ASP B . n 
B 2 81  SER 81  84  84  SER SER B . n 
B 2 82  TYR 82  85  85  TYR TYR B . n 
B 2 83  THR 83  86  86  THR THR B . n 
B 2 84  THR 84  87  87  THR THR B . n 
B 2 85  ASN 85  88  88  ASN ASN B . n 
B 2 86  LYS 86  89  89  LYS LYS B . n 
B 2 87  VAL 87  90  90  VAL VAL B . n 
B 2 88  HIS 88  91  91  HIS HIS B . n 
B 2 89  ALA 89  92  92  ALA ALA B . n 
B 2 90  ILE 90  93  93  ILE ILE B . n 
B 2 91  PRO 91  94  94  PRO PRO B . n 
B 2 92  LEU 92  95  95  LEU LEU B . n 
B 2 93  ARG 93  96  96  ARG ARG B . n 
B 2 94  SER 94  97  97  SER SER B . n 
B 2 95  SER 95  98  98  SER SER B . n 
B 2 96  TRP 96  99  99  TRP TRP B . n 
B 2 97  VAL 97  100 100 VAL VAL B . n 
B 2 98  MET 98  101 101 MET MET B . n 
B 2 99  THR 99  102 102 THR THR B . n 
B 2 100 CYS 100 103 103 CYS CYS B . n 
B 2 101 ALA 101 104 104 ALA ALA B . n 
B 2 102 TYR 102 105 105 TYR TYR B . n 
B 2 103 ALA 103 106 106 ALA ALA B . n 
B 2 104 PRO 104 107 107 PRO PRO B . n 
B 2 105 SER 105 108 108 SER SER B . n 
B 2 106 GLY 106 109 109 GLY GLY B . n 
B 2 107 ASN 107 110 110 ASN ASN B . n 
B 2 108 TYR 108 111 111 TYR TYR B . n 
B 2 109 VAL 109 112 112 VAL VAL B . n 
B 2 110 ALA 110 113 113 ALA ALA B . n 
B 2 111 CYS 111 114 114 CYS CYS B . n 
B 2 112 GLY 112 115 115 GLY GLY B . n 
B 2 113 GLY 113 116 116 GLY GLY B . n 
B 2 114 LEU 114 117 117 LEU LEU B . n 
B 2 115 ASP 115 118 118 ASP ASP B . n 
B 2 116 ASN 116 119 119 ASN ASN B . n 
B 2 117 ILE 117 120 120 ILE ILE B . n 
B 2 118 CYS 118 121 121 CYS CYS B . n 
B 2 119 SER 119 122 122 SER SER B . n 
B 2 120 ILE 120 123 123 ILE ILE B . n 
B 2 121 TYR 121 124 124 TYR TYR B . n 
B 2 122 ASN 122 125 125 ASN ASN B . n 
B 2 123 LEU 123 126 126 LEU LEU B . n 
B 2 124 LYS 124 127 127 LYS LYS B . n 
B 2 125 THR 125 128 128 THR THR B . n 
B 2 126 ARG 126 129 129 ARG ARG B . n 
B 2 127 GLU 127 130 130 GLU GLU B . n 
B 2 128 GLY 128 131 131 GLY GLY B . n 
B 2 129 ASN 129 132 132 ASN ASN B . n 
B 2 130 VAL 130 133 133 VAL VAL B . n 
B 2 131 ARG 131 134 134 ARG ARG B . n 
B 2 132 VAL 132 135 135 VAL VAL B . n 
B 2 133 SER 133 136 136 SER SER B . n 
B 2 134 ARG 134 137 137 ARG ARG B . n 
B 2 135 GLU 135 138 138 GLU GLU B . n 
B 2 136 LEU 136 139 139 LEU LEU B . n 
B 2 137 ALA 137 140 140 ALA ALA B . n 
B 2 138 GLY 138 141 141 GLY GLY B . n 
B 2 139 HIS 139 142 142 HIS HIS B . n 
B 2 140 THR 140 143 143 THR THR B . n 
B 2 141 GLY 141 144 144 GLY GLY B . n 
B 2 142 TYR 142 145 145 TYR TYR B . n 
B 2 143 LEU 143 146 146 LEU LEU B . n 
B 2 144 SER 144 147 147 SER SER B . n 
B 2 145 CYS 145 148 148 CYS CYS B . n 
B 2 146 CYS 146 149 149 CYS CYS B . n 
B 2 147 ARG 147 150 150 ARG ARG B . n 
B 2 148 PHE 148 151 151 PHE PHE B . n 
B 2 149 LEU 149 152 152 LEU LEU B . n 
B 2 150 ASP 150 153 153 ASP ASP B . n 
B 2 151 ASP 151 154 154 ASP ASP B . n 
B 2 152 ASN 152 155 155 ASN ASN B . n 
B 2 153 GLN 153 156 156 GLN GLN B . n 
B 2 154 ILE 154 157 157 ILE ILE B . n 
B 2 155 VAL 155 158 158 VAL VAL B . n 
B 2 156 THR 156 159 159 THR THR B . n 
B 2 157 SER 157 160 160 SER SER B . n 
B 2 158 SER 158 161 161 SER SER B . n 
B 2 159 GLY 159 162 162 GLY GLY B . n 
B 2 160 ASP 160 163 163 ASP ASP B . n 
B 2 161 THR 161 164 164 THR THR B . n 
B 2 162 THR 162 165 165 THR THR B . n 
B 2 163 CYS 163 166 166 CYS CYS B . n 
B 2 164 ALA 164 167 167 ALA ALA B . n 
B 2 165 LEU 165 168 168 LEU LEU B . n 
B 2 166 TRP 166 169 169 TRP TRP B . n 
B 2 167 ASP 167 170 170 ASP ASP B . n 
B 2 168 ILE 168 171 171 ILE ILE B . n 
B 2 169 GLU 169 172 172 GLU GLU B . n 
B 2 170 THR 170 173 173 THR THR B . n 
B 2 171 GLY 171 174 174 GLY GLY B . n 
B 2 172 GLN 172 175 175 GLN GLN B . n 
B 2 173 GLN 173 176 176 GLN GLN B . n 
B 2 174 THR 174 177 177 THR THR B . n 
B 2 175 THR 175 178 178 THR THR B . n 
B 2 176 THR 176 179 179 THR THR B . n 
B 2 177 PHE 177 180 180 PHE PHE B . n 
B 2 178 THR 178 181 181 THR THR B . n 
B 2 179 GLY 179 182 182 GLY GLY B . n 
B 2 180 HIS 180 183 183 HIS HIS B . n 
B 2 181 THR 181 184 184 THR THR B . n 
B 2 182 GLY 182 185 185 GLY GLY B . n 
B 2 183 ASP 183 186 186 ASP ASP B . n 
B 2 184 VAL 184 187 187 VAL VAL B . n 
B 2 185 MET 185 188 188 MET MET B . n 
B 2 186 SER 186 189 189 SER SER B . n 
B 2 187 LEU 187 190 190 LEU LEU B . n 
B 2 188 SER 188 191 191 SER SER B . n 
B 2 189 LEU 189 192 192 LEU LEU B . n 
B 2 190 ALA 190 193 193 ALA ALA B . n 
B 2 191 PRO 191 194 194 PRO PRO B . n 
B 2 192 ASP 192 195 195 ASP ASP B . n 
B 2 193 THR 193 196 196 THR THR B . n 
B 2 194 ARG 194 197 197 ARG ARG B . n 
B 2 195 LEU 195 198 198 LEU LEU B . n 
B 2 196 PHE 196 199 199 PHE PHE B . n 
B 2 197 VAL 197 200 200 VAL VAL B . n 
B 2 198 SER 198 201 201 SER SER B . n 
B 2 199 GLY 199 202 202 GLY GLY B . n 
B 2 200 ALA 200 203 203 ALA ALA B . n 
B 2 201 CYS 201 204 204 CYS CYS B . n 
B 2 202 ASP 202 205 205 ASP ASP B . n 
B 2 203 ALA 203 206 206 ALA ALA B . n 
B 2 204 SER 204 207 207 SER SER B . n 
B 2 205 ALA 205 208 208 ALA ALA B . n 
B 2 206 LYS 206 209 209 LYS LYS B . n 
B 2 207 LEU 207 210 210 LEU LEU B . n 
B 2 208 TRP 208 211 211 TRP TRP B . n 
B 2 209 ASP 209 212 212 ASP ASP B . n 
B 2 210 VAL 210 213 213 VAL VAL B . n 
B 2 211 ARG 211 214 214 ARG ARG B . n 
B 2 212 GLU 212 215 215 GLU GLU B . n 
B 2 213 GLY 213 216 216 GLY GLY B . n 
B 2 214 MET 214 217 217 MET MET B . n 
B 2 215 CYS 215 218 218 CYS CYS B . n 
B 2 216 ARG 216 219 219 ARG ARG B . n 
B 2 217 GLN 217 220 220 GLN GLN B . n 
B 2 218 THR 218 221 221 THR THR B . n 
B 2 219 PHE 219 222 222 PHE PHE B . n 
B 2 220 THR 220 223 223 THR THR B . n 
B 2 221 GLY 221 224 224 GLY GLY B . n 
B 2 222 HIS 222 225 225 HIS HIS B . n 
B 2 223 GLU 223 226 226 GLU GLU B . n 
B 2 224 SER 224 227 227 SER SER B . n 
B 2 225 ASP 225 228 228 ASP ASP B . n 
B 2 226 ILE 226 229 229 ILE ILE B . n 
B 2 227 ASN 227 230 230 ASN ASN B . n 
B 2 228 ALA 228 231 231 ALA ALA B . n 
B 2 229 ILE 229 232 232 ILE ILE B . n 
B 2 230 CYS 230 233 233 CYS CYS B . n 
B 2 231 PHE 231 234 234 PHE PHE B . n 
B 2 232 PHE 232 235 235 PHE PHE B . n 
B 2 233 PRO 233 236 236 PRO PRO B . n 
B 2 234 ASN 234 237 237 ASN ASN B . n 
B 2 235 GLY 235 238 238 GLY GLY B . n 
B 2 236 ASN 236 239 239 ASN ASN B . n 
B 2 237 ALA 237 240 240 ALA ALA B . n 
B 2 238 PHE 238 241 241 PHE PHE B . n 
B 2 239 ALA 239 242 242 ALA ALA B . n 
B 2 240 THR 240 243 243 THR THR B . n 
B 2 241 GLY 241 244 244 GLY GLY B . n 
B 2 242 SER 242 245 245 SER SER B . n 
B 2 243 ASP 243 246 246 ASP ASP B . n 
B 2 244 ASP 244 247 247 ASP ASP B . n 
B 2 245 ALA 245 248 248 ALA ALA B . n 
B 2 246 THR 246 249 249 THR THR B . n 
B 2 247 CYS 247 250 250 CYS CYS B . n 
B 2 248 ARG 248 251 251 ARG ARG B . n 
B 2 249 LEU 249 252 252 LEU LEU B . n 
B 2 250 PHE 250 253 253 PHE PHE B . n 
B 2 251 ASP 251 254 254 ASP ASP B . n 
B 2 252 LEU 252 255 255 LEU LEU B . n 
B 2 253 ARG 253 256 256 ARG ARG B . n 
B 2 254 ALA 254 257 257 ALA ALA B . n 
B 2 255 ASP 255 258 258 ASP ASP B . n 
B 2 256 GLN 256 259 259 GLN GLN B . n 
B 2 257 GLU 257 260 260 GLU GLU B . n 
B 2 258 LEU 258 261 261 LEU LEU B . n 
B 2 259 MET 259 262 262 MET MET B . n 
B 2 260 THR 260 263 263 THR THR B . n 
B 2 261 TYR 261 264 264 TYR TYR B . n 
B 2 262 SER 262 265 265 SER SER B . n 
B 2 263 HIS 263 266 266 HIS HIS B . n 
B 2 264 ASP 264 267 267 ASP ASP B . n 
B 2 265 ASN 265 268 268 ASN ASN B . n 
B 2 266 ILE 266 269 269 ILE ILE B . n 
B 2 267 ILE 267 270 270 ILE ILE B . n 
B 2 268 CYS 268 271 271 CYS CYS B . n 
B 2 269 GLY 269 272 272 GLY GLY B . n 
B 2 270 ILE 270 273 273 ILE ILE B . n 
B 2 271 THR 271 274 274 THR THR B . n 
B 2 272 SER 272 275 275 SER SER B . n 
B 2 273 VAL 273 276 276 VAL VAL B . n 
B 2 274 SER 274 277 277 SER SER B . n 
B 2 275 PHE 275 278 278 PHE PHE B . n 
B 2 276 SER 276 279 279 SER SER B . n 
B 2 277 LYS 277 280 280 LYS LYS B . n 
B 2 278 SER 278 281 281 SER SER B . n 
B 2 279 GLY 279 282 282 GLY GLY B . n 
B 2 280 ARG 280 283 283 ARG ARG B . n 
B 2 281 LEU 281 284 284 LEU LEU B . n 
B 2 282 LEU 282 285 285 LEU LEU B . n 
B 2 283 LEU 283 286 286 LEU LEU B . n 
B 2 284 ALA 284 287 287 ALA ALA B . n 
B 2 285 GLY 285 288 288 GLY GLY B . n 
B 2 286 TYR 286 289 289 TYR TYR B . n 
B 2 287 ASP 287 290 290 ASP ASP B . n 
B 2 288 ASP 288 291 291 ASP ASP B . n 
B 2 289 PHE 289 292 292 PHE PHE B . n 
B 2 290 ASN 290 293 293 ASN ASN B . n 
B 2 291 CYS 291 294 294 CYS CYS B . n 
B 2 292 ASN 292 295 295 ASN ASN B . n 
B 2 293 VAL 293 296 296 VAL VAL B . n 
B 2 294 TRP 294 297 297 TRP TRP B . n 
B 2 295 ASP 295 298 298 ASP ASP B . n 
B 2 296 ALA 296 299 299 ALA ALA B . n 
B 2 297 LEU 297 300 300 LEU LEU B . n 
B 2 298 LYS 298 301 301 LYS LYS B . n 
B 2 299 ALA 299 302 302 ALA ALA B . n 
B 2 300 ASP 300 303 303 ASP ASP B . n 
B 2 301 ARG 301 304 304 ARG ARG B . n 
B 2 302 ALA 302 305 305 ALA ALA B . n 
B 2 303 GLY 303 306 306 GLY GLY B . n 
B 2 304 VAL 304 307 307 VAL VAL B . n 
B 2 305 LEU 305 308 308 LEU LEU B . n 
B 2 306 ALA 306 309 309 ALA ALA B . n 
B 2 307 GLY 307 310 310 GLY GLY B . n 
B 2 308 HIS 308 311 311 HIS HIS B . n 
B 2 309 ASP 309 312 312 ASP ASP B . n 
B 2 310 ASN 310 313 313 ASN ASN B . n 
B 2 311 ARG 311 314 314 ARG ARG B . n 
B 2 312 VAL 312 315 315 VAL VAL B . n 
B 2 313 SER 313 316 316 SER SER B . n 
B 2 314 CYS 314 317 317 CYS CYS B . n 
B 2 315 LEU 315 318 318 LEU LEU B . n 
B 2 316 GLY 316 319 319 GLY GLY B . n 
B 2 317 VAL 317 320 320 VAL VAL B . n 
B 2 318 THR 318 321 321 THR THR B . n 
B 2 319 ASP 319 322 322 ASP ASP B . n 
B 2 320 ASP 320 323 323 ASP ASP B . n 
B 2 321 GLY 321 324 324 GLY GLY B . n 
B 2 322 MET 322 325 325 MET MET B . n 
B 2 323 ALA 323 326 326 ALA ALA B . n 
B 2 324 VAL 324 327 327 VAL VAL B . n 
B 2 325 ALA 325 328 328 ALA ALA B . n 
B 2 326 THR 326 329 329 THR THR B . n 
B 2 327 GLY 327 330 330 GLY GLY B . n 
B 2 328 SER 328 331 331 SER SER B . n 
B 2 329 TRP 329 332 332 TRP TRP B . n 
B 2 330 ASP 330 333 333 ASP ASP B . n 
B 2 331 SER 331 334 334 SER SER B . n 
B 2 332 PHE 332 335 335 PHE PHE B . n 
B 2 333 LEU 333 336 336 LEU LEU B . n 
B 2 334 LYS 334 337 337 LYS LYS B . n 
B 2 335 ILE 335 338 338 ILE ILE B . n 
B 2 336 TRP 336 339 339 TRP TRP B . n 
B 2 337 ASN 337 340 340 ASN ASN B . n 
C 3 1   THR 1   4   4   THR THR C . n 
C 3 2   LEU 2   5   5   LEU LEU C . n 
C 3 3   SER 3   6   6   SER SER C . n 
C 3 4   ALA 4   7   7   ALA ALA C . n 
C 3 5   GLU 5   8   8   GLU GLU C . n 
C 3 6   ASP 6   9   9   ASP ASP C . n 
C 3 7   LYS 7   10  10  LYS LYS C . n 
C 3 8   ALA 8   11  11  ALA ALA C . n 
C 3 9   ALA 9   12  12  ALA ALA C . n 
C 3 10  VAL 10  13  13  VAL VAL C . n 
C 3 11  GLU 11  14  14  GLU GLU C . n 
C 3 12  ARG 12  15  15  ARG ARG C . n 
C 3 13  SER 13  16  16  SER SER C . n 
C 3 14  LYS 14  17  17  LYS LYS C . n 
C 3 15  MET 15  18  18  MET MET C . n 
C 3 16  ILE 16  19  19  ILE ILE C . n 
C 3 17  ASP 17  20  20  ASP ASP C . n 
C 3 18  ARG 18  21  21  ARG ARG C . n 
C 3 19  ASN 19  22  22  ASN ASN C . n 
C 3 20  LEU 20  23  23  LEU LEU C . n 
C 3 21  ARG 21  24  24  ARG ARG C . n 
C 3 22  GLU 22  25  25  GLU GLU C . n 
C 3 23  ASP 23  26  26  ASP ASP C . n 
C 3 24  GLY 24  27  27  GLY GLY C . n 
C 3 25  GLU 25  28  28  GLU GLU C . n 
C 3 26  LYS 26  29  29  LYS LYS C . n 
C 3 27  ALA 27  30  30  ALA ALA C . n 
C 3 28  ALA 28  31  31  ALA ALA C . n 
C 3 29  ARG 29  32  32  ARG ARG C . n 
C 3 30  GLU 30  33  33  GLU GLU C . n 
C 3 31  VAL 31  34  34  VAL VAL C . n 
C 3 32  LYS 32  35  35  LYS LYS C . n 
C 3 33  LEU 33  36  36  LEU LEU C . n 
C 3 34  LEU 34  37  37  LEU LEU C . n 
C 3 35  LEU 35  38  38  LEU LEU C . n 
C 3 36  LEU 36  39  39  LEU LEU C . n 
C 3 37  GLY 37  40  40  GLY GLY C . n 
C 3 38  ALA 38  41  41  ALA ALA C . n 
C 3 39  GLY 39  42  42  GLY GLY C . n 
C 3 40  GLU 40  43  43  GLU GLU C . n 
C 3 41  SER 41  44  44  SER SER C . n 
C 3 42  GLY 42  45  45  GLY GLY C . n 
C 3 43  LYS 43  46  46  LYS LYS C . n 
C 3 44  SER 44  47  47  SER SER C . n 
C 3 45  THR 45  48  48  THR THR C . n 
C 3 46  ILE 46  49  49  ILE ILE C . n 
C 3 47  VAL 47  50  50  VAL VAL C . n 
C 3 48  LYS 48  51  51  LYS LYS C . n 
C 3 49  GLN 49  52  52  GLN GLN C . n 
C 3 50  MET 50  53  53  MET MET C . n 
C 3 51  LYS 51  54  ?   ?   ?   C . n 
C 3 52  ILE 52  55  ?   ?   ?   C . n 
C 3 53  ILE 53  56  ?   ?   ?   C . n 
C 3 54  HIS 54  57  ?   ?   ?   C . n 
C 3 55  GLU 55  58  ?   ?   ?   C . n 
C 3 56  ALA 56  59  ?   ?   ?   C . n 
C 3 57  GLY 57  60  ?   ?   ?   C . n 
C 3 58  TYR 58  61  ?   ?   ?   C . n 
C 3 59  SER 59  62  ?   ?   ?   C . n 
C 3 60  GLU 60  63  ?   ?   ?   C . n 
C 3 61  GLU 61  64  ?   ?   ?   C . n 
C 3 62  GLU 62  65  ?   ?   ?   C . n 
C 3 63  CYS 63  66  ?   ?   ?   C . n 
C 3 64  LYS 64  67  ?   ?   ?   C . n 
C 3 65  GLN 65  68  ?   ?   ?   C . n 
C 3 66  TYR 66  69  ?   ?   ?   C . n 
C 3 67  LYS 67  70  ?   ?   ?   C . n 
C 3 68  ALA 68  71  ?   ?   ?   C . n 
C 3 69  VAL 69  72  ?   ?   ?   C . n 
C 3 70  VAL 70  73  ?   ?   ?   C . n 
C 3 71  TYR 71  74  ?   ?   ?   C . n 
C 3 72  SER 72  75  ?   ?   ?   C . n 
C 3 73  ASN 73  76  ?   ?   ?   C . n 
C 3 74  THR 74  77  ?   ?   ?   C . n 
C 3 75  ILE 75  78  ?   ?   ?   C . n 
C 3 76  GLN 76  79  ?   ?   ?   C . n 
C 3 77  SER 77  80  ?   ?   ?   C . n 
C 3 78  ILE 78  81  ?   ?   ?   C . n 
C 3 79  ILE 79  82  ?   ?   ?   C . n 
C 3 80  ALA 80  83  ?   ?   ?   C . n 
C 3 81  ILE 81  84  ?   ?   ?   C . n 
C 3 82  ILE 82  85  ?   ?   ?   C . n 
C 3 83  ARG 83  86  ?   ?   ?   C . n 
C 3 84  ALA 84  87  ?   ?   ?   C . n 
C 3 85  MET 85  88  ?   ?   ?   C . n 
C 3 86  GLY 86  89  ?   ?   ?   C . n 
C 3 87  ARG 87  90  ?   ?   ?   C . n 
C 3 88  LEU 88  91  ?   ?   ?   C . n 
C 3 89  LYS 89  92  ?   ?   ?   C . n 
C 3 90  ILE 90  93  ?   ?   ?   C . n 
C 3 91  ASP 91  94  ?   ?   ?   C . n 
C 3 92  PHE 92  95  ?   ?   ?   C . n 
C 3 93  GLY 93  96  ?   ?   ?   C . n 
C 3 94  ASP 94  97  ?   ?   ?   C . n 
C 3 95  SER 95  98  ?   ?   ?   C . n 
C 3 96  ALA 96  99  ?   ?   ?   C . n 
C 3 97  ARG 97  100 ?   ?   ?   C . n 
C 3 98  ALA 98  101 ?   ?   ?   C . n 
C 3 99  ASP 99  102 ?   ?   ?   C . n 
C 3 100 ASP 100 103 ?   ?   ?   C . n 
C 3 101 ALA 101 104 ?   ?   ?   C . n 
C 3 102 ARG 102 105 ?   ?   ?   C . n 
C 3 103 GLN 103 106 ?   ?   ?   C . n 
C 3 104 LEU 104 107 ?   ?   ?   C . n 
C 3 105 PHE 105 108 ?   ?   ?   C . n 
C 3 106 VAL 106 109 ?   ?   ?   C . n 
C 3 107 LEU 107 110 ?   ?   ?   C . n 
C 3 108 ALA 108 111 ?   ?   ?   C . n 
C 3 109 GLY 109 112 ?   ?   ?   C . n 
C 3 110 ALA 110 113 ?   ?   ?   C . n 
C 3 111 ALA 111 114 ?   ?   ?   C . n 
C 3 112 GLU 112 115 ?   ?   ?   C . n 
C 3 113 GLU 113 116 ?   ?   ?   C . n 
C 3 114 GLY 114 117 ?   ?   ?   C . n 
C 3 115 PHE 115 118 ?   ?   ?   C . n 
C 3 116 MET 116 119 ?   ?   ?   C . n 
C 3 117 THR 117 120 ?   ?   ?   C . n 
C 3 118 ALA 118 121 ?   ?   ?   C . n 
C 3 119 GLU 119 122 ?   ?   ?   C . n 
C 3 120 LEU 120 123 ?   ?   ?   C . n 
C 3 121 ALA 121 124 ?   ?   ?   C . n 
C 3 122 GLY 122 125 ?   ?   ?   C . n 
C 3 123 VAL 123 126 ?   ?   ?   C . n 
C 3 124 ILE 124 127 ?   ?   ?   C . n 
C 3 125 LYS 125 128 ?   ?   ?   C . n 
C 3 126 ARG 126 129 ?   ?   ?   C . n 
C 3 127 LEU 127 130 ?   ?   ?   C . n 
C 3 128 TRP 128 131 ?   ?   ?   C . n 
C 3 129 LYS 129 132 ?   ?   ?   C . n 
C 3 130 ASP 130 133 ?   ?   ?   C . n 
C 3 131 SER 131 134 ?   ?   ?   C . n 
C 3 132 GLY 132 135 ?   ?   ?   C . n 
C 3 133 VAL 133 136 ?   ?   ?   C . n 
C 3 134 GLN 134 137 ?   ?   ?   C . n 
C 3 135 ALA 135 138 ?   ?   ?   C . n 
C 3 136 CYS 136 139 ?   ?   ?   C . n 
C 3 137 PHE 137 140 ?   ?   ?   C . n 
C 3 138 ASN 138 141 ?   ?   ?   C . n 
C 3 139 ARG 139 142 ?   ?   ?   C . n 
C 3 140 SER 140 143 ?   ?   ?   C . n 
C 3 141 ARG 141 144 ?   ?   ?   C . n 
C 3 142 GLU 142 145 ?   ?   ?   C . n 
C 3 143 TYR 143 146 ?   ?   ?   C . n 
C 3 144 GLN 144 147 ?   ?   ?   C . n 
C 3 145 LEU 145 148 ?   ?   ?   C . n 
C 3 146 ASN 146 149 ?   ?   ?   C . n 
C 3 147 ASP 147 150 ?   ?   ?   C . n 
C 3 148 SER 148 151 ?   ?   ?   C . n 
C 3 149 ALA 149 152 ?   ?   ?   C . n 
C 3 150 ALA 150 153 ?   ?   ?   C . n 
C 3 151 TYR 151 154 ?   ?   ?   C . n 
C 3 152 TYR 152 155 ?   ?   ?   C . n 
C 3 153 LEU 153 156 ?   ?   ?   C . n 
C 3 154 ASN 154 157 ?   ?   ?   C . n 
C 3 155 ASP 155 158 ?   ?   ?   C . n 
C 3 156 LEU 156 159 ?   ?   ?   C . n 
C 3 157 ASP 157 160 ?   ?   ?   C . n 
C 3 158 ARG 158 161 ?   ?   ?   C . n 
C 3 159 ILE 159 162 ?   ?   ?   C . n 
C 3 160 ALA 160 163 ?   ?   ?   C . n 
C 3 161 GLN 161 164 ?   ?   ?   C . n 
C 3 162 PRO 162 165 ?   ?   ?   C . n 
C 3 163 ASN 163 166 ?   ?   ?   C . n 
C 3 164 TYR 164 167 ?   ?   ?   C . n 
C 3 165 ILE 165 168 ?   ?   ?   C . n 
C 3 166 PRO 166 169 ?   ?   ?   C . n 
C 3 167 THR 167 170 ?   ?   ?   C . n 
C 3 168 GLN 168 171 ?   ?   ?   C . n 
C 3 169 GLN 169 172 ?   ?   ?   C . n 
C 3 170 ASP 170 173 ?   ?   ?   C . n 
C 3 171 VAL 171 174 ?   ?   ?   C . n 
C 3 172 LEU 172 175 ?   ?   ?   C . n 
C 3 173 ARG 173 176 ?   ?   ?   C . n 
C 3 174 THR 174 177 ?   ?   ?   C . n 
C 3 175 ARG 175 178 ?   ?   ?   C . n 
C 3 176 VAL 176 179 ?   ?   ?   C . n 
C 3 177 LYS 177 180 ?   ?   ?   C . n 
C 3 178 THR 178 181 ?   ?   ?   C . n 
C 3 179 THR 179 182 182 THR THR C . n 
C 3 180 GLY 180 183 183 GLY GLY C . n 
C 3 181 ILE 181 184 184 ILE ILE C . n 
C 3 182 VAL 182 185 185 VAL VAL C . n 
C 3 183 GLU 183 186 186 GLU GLU C . n 
C 3 184 THR 184 187 187 THR THR C . n 
C 3 185 HIS 185 188 188 HIS HIS C . n 
C 3 186 PHE 186 189 189 PHE PHE C . n 
C 3 187 THR 187 190 190 THR THR C . n 
C 3 188 PHE 188 191 191 PHE PHE C . n 
C 3 189 LYS 189 192 192 LYS LYS C . n 
C 3 190 ASP 190 193 193 ASP ASP C . n 
C 3 191 LEU 191 194 194 LEU LEU C . n 
C 3 192 HIS 192 195 195 HIS HIS C . n 
C 3 193 PHE 193 196 196 PHE PHE C . n 
C 3 194 LYS 194 197 197 LYS LYS C . n 
C 3 195 MET 195 198 198 MET MET C . n 
C 3 196 PHE 196 199 199 PHE PHE C . n 
C 3 197 ASP 197 200 200 ASP ASP C . n 
C 3 198 VAL 198 201 201 VAL VAL C . n 
C 3 199 GLY 199 202 202 GLY GLY C . n 
C 3 200 ALA 200 203 203 ALA ALA C . n 
C 3 201 GLN 201 204 204 GLN GLN C . n 
C 3 202 ARG 202 205 205 ARG ARG C . n 
C 3 203 SER 203 206 206 SER SER C . n 
C 3 204 GLU 204 207 207 GLU GLU C . n 
C 3 205 ARG 205 208 208 ARG ARG C . n 
C 3 206 LYS 206 209 209 LYS LYS C . n 
C 3 207 LYS 207 210 210 LYS LYS C . n 
C 3 208 TRP 208 211 211 TRP TRP C . n 
C 3 209 ILE 209 212 212 ILE ILE C . n 
C 3 210 HIS 210 213 213 HIS HIS C . n 
C 3 211 CYS 211 214 214 CYS CYS C . n 
C 3 212 PHE 212 215 215 PHE PHE C . n 
C 3 213 GLU 213 216 216 GLU GLU C . n 
C 3 214 GLY 214 217 217 GLY GLY C . n 
C 3 215 VAL 215 218 218 VAL VAL C . n 
C 3 216 THR 216 219 219 THR THR C . n 
C 3 217 ALA 217 220 220 ALA ALA C . n 
C 3 218 ILE 218 221 221 ILE ILE C . n 
C 3 219 ILE 219 222 222 ILE ILE C . n 
C 3 220 PHE 220 223 223 PHE PHE C . n 
C 3 221 CYS 221 224 224 CYS CYS C . n 
C 3 222 VAL 222 225 225 VAL VAL C . n 
C 3 223 ALA 223 226 226 ALA ALA C . n 
C 3 224 LEU 224 227 227 LEU LEU C . n 
C 3 225 SER 225 228 228 SER SER C . n 
C 3 226 ASP 226 229 229 ASP ASP C . n 
C 3 227 TYR 227 230 230 TYR TYR C . n 
C 3 228 ASP 228 231 231 ASP ASP C . n 
C 3 229 LEU 229 232 232 LEU LEU C . n 
C 3 230 VAL 230 233 233 VAL VAL C . n 
C 3 231 LEU 231 234 ?   ?   ?   C . n 
C 3 232 ALA 232 235 ?   ?   ?   C . n 
C 3 233 GLU 233 236 ?   ?   ?   C . n 
C 3 234 ASP 234 237 ?   ?   ?   C . n 
C 3 235 GLU 235 238 ?   ?   ?   C . n 
C 3 236 GLU 236 239 ?   ?   ?   C . n 
C 3 237 MET 237 240 ?   ?   ?   C . n 
C 3 238 ASN 238 241 241 ASN ASN C . n 
C 3 239 ARG 239 242 242 ARG ARG C . n 
C 3 240 MET 240 243 243 MET MET C . n 
C 3 241 HIS 241 244 244 HIS HIS C . n 
C 3 242 GLU 242 245 245 GLU GLU C . n 
C 3 243 SER 243 246 246 SER SER C . n 
C 3 244 MET 244 247 247 MET MET C . n 
C 3 245 LYS 245 248 248 LYS LYS C . n 
C 3 246 LEU 246 249 249 LEU LEU C . n 
C 3 247 PHE 247 250 250 PHE PHE C . n 
C 3 248 ASP 248 251 251 ASP ASP C . n 
C 3 249 SER 249 252 252 SER SER C . n 
C 3 250 ILE 250 253 253 ILE ILE C . n 
C 3 251 CYS 251 254 254 CYS CYS C . n 
C 3 252 ASN 252 255 255 ASN ASN C . n 
C 3 253 ASN 253 256 256 ASN ASN C . n 
C 3 254 LYS 254 257 257 LYS LYS C . n 
C 3 255 TRP 255 258 258 TRP TRP C . n 
C 3 256 PHE 256 259 259 PHE PHE C . n 
C 3 257 THR 257 260 260 THR THR C . n 
C 3 258 ASP 258 261 261 ASP ASP C . n 
C 3 259 THR 259 262 262 THR THR C . n 
C 3 260 SER 260 263 263 SER SER C . n 
C 3 261 ILE 261 264 264 ILE ILE C . n 
C 3 262 ILE 262 265 265 ILE ILE C . n 
C 3 263 LEU 263 266 266 LEU LEU C . n 
C 3 264 PHE 264 267 267 PHE PHE C . n 
C 3 265 LEU 265 268 268 LEU LEU C . n 
C 3 266 ASN 266 269 269 ASN ASN C . n 
C 3 267 LYS 267 270 270 LYS LYS C . n 
C 3 268 LYS 268 271 271 LYS LYS C . n 
C 3 269 ASP 269 272 272 ASP ASP C . n 
C 3 270 LEU 270 273 273 LEU LEU C . n 
C 3 271 PHE 271 274 274 PHE PHE C . n 
C 3 272 GLU 272 275 275 GLU GLU C . n 
C 3 273 GLU 273 276 276 GLU GLU C . n 
C 3 274 LYS 274 277 277 LYS LYS C . n 
C 3 275 ILE 275 278 278 ILE ILE C . n 
C 3 276 LYS 276 279 279 LYS LYS C . n 
C 3 277 LYS 277 280 280 LYS LYS C . n 
C 3 278 SER 278 281 281 SER SER C . n 
C 3 279 PRO 279 282 282 PRO PRO C . n 
C 3 280 LEU 280 283 283 LEU LEU C . n 
C 3 281 THR 281 284 284 THR THR C . n 
C 3 282 ILE 282 285 285 ILE ILE C . n 
C 3 283 CYS 283 286 286 CYS CYS C . n 
C 3 284 TYR 284 287 287 TYR TYR C . n 
C 3 285 PRO 285 288 288 PRO PRO C . n 
C 3 286 GLU 286 289 289 GLU GLU C . n 
C 3 287 TYR 287 290 290 TYR TYR C . n 
C 3 288 ALA 288 291 291 ALA ALA C . n 
C 3 289 GLY 289 292 292 GLY GLY C . n 
C 3 290 SER 290 293 293 SER SER C . n 
C 3 291 ASN 291 294 294 ASN ASN C . n 
C 3 292 THR 292 295 295 THR THR C . n 
C 3 293 TYR 293 296 296 TYR TYR C . n 
C 3 294 GLU 294 297 297 GLU GLU C . n 
C 3 295 GLU 295 298 298 GLU GLU C . n 
C 3 296 ALA 296 299 299 ALA ALA C . n 
C 3 297 ALA 297 300 300 ALA ALA C . n 
C 3 298 ALA 298 301 301 ALA ALA C . n 
C 3 299 TYR 299 302 302 TYR TYR C . n 
C 3 300 ILE 300 303 303 ILE ILE C . n 
C 3 301 GLN 301 304 304 GLN GLN C . n 
C 3 302 CYS 302 305 305 CYS CYS C . n 
C 3 303 GLN 303 306 306 GLN GLN C . n 
C 3 304 PHE 304 307 307 PHE PHE C . n 
C 3 305 GLU 305 308 308 GLU GLU C . n 
C 3 306 ASP 306 309 309 ASP ASP C . n 
C 3 307 LEU 307 310 310 LEU LEU C . n 
C 3 308 ASN 308 311 311 ASN ASN C . n 
C 3 309 LYS 309 312 312 LYS LYS C . n 
C 3 310 ARG 310 313 313 ARG ARG C . n 
C 3 311 LYS 311 314 314 LYS LYS C . n 
C 3 312 ASP 312 315 315 ASP ASP C . n 
C 3 313 THR 313 316 316 THR THR C . n 
C 3 314 LYS 314 317 317 LYS LYS C . n 
C 3 315 GLU 315 318 318 GLU GLU C . n 
C 3 316 ILE 316 319 319 ILE ILE C . n 
C 3 317 TYR 317 320 320 TYR TYR C . n 
C 3 318 THR 318 321 321 THR THR C . n 
C 3 319 HIS 319 322 322 HIS HIS C . n 
C 3 320 PHE 320 323 323 PHE PHE C . n 
C 3 321 THR 321 324 324 THR THR C . n 
C 3 322 CYS 322 325 325 CYS CYS C . n 
C 3 323 SER 323 326 326 SER SER C . n 
C 3 324 THR 324 327 327 THR THR C . n 
C 3 325 ASP 325 328 328 ASP ASP C . n 
C 3 326 THR 326 329 329 THR THR C . n 
C 3 327 LYS 327 330 330 LYS LYS C . n 
C 3 328 ASN 328 331 331 ASN ASN C . n 
C 3 329 VAL 329 332 332 VAL VAL C . n 
C 3 330 GLN 330 333 333 GLN GLN C . n 
C 3 331 PHE 331 334 334 PHE PHE C . n 
C 3 332 VAL 332 335 335 VAL VAL C . n 
C 3 333 PHE 333 336 336 PHE PHE C . n 
C 3 334 ASP 334 337 337 ASP ASP C . n 
C 3 335 ALA 335 338 338 ALA ALA C . n 
C 3 336 VAL 336 339 339 VAL VAL C . n 
C 3 337 THR 337 340 340 THR THR C . n 
C 3 338 ASP 338 341 341 ASP ASP C . n 
C 3 339 VAL 339 342 342 VAL VAL C . n 
C 3 340 ILE 340 343 343 ILE ILE C . n 
C 3 341 ILE 341 344 344 ILE ILE C . n 
C 3 342 LYS 342 345 345 LYS LYS C . n 
C 3 343 ASN 343 346 346 ASN ASN C . n 
C 3 344 ASN 344 347 347 ASN ASN C . n 
C 3 345 LEU 345 348 348 LEU LEU C . n 
C 3 346 LYS 346 349 349 LYS LYS C . n 
C 3 347 ASP 347 350 350 ASP ASP C . n 
C 3 348 CYS 348 351 351 CYS CYS C . n 
C 3 349 GLY 349 352 352 GLY GLY C . n 
C 3 350 LEU 350 353 353 LEU LEU C . n 
C 3 351 PHE 351 354 354 PHE PHE C . n 
D 4 1   SER 1   8   8   SER SER G . n 
D 4 2   ILE 2   9   9   ILE ILE G . n 
D 4 3   ALA 3   10  10  ALA ALA G . n 
D 4 4   GLN 4   11  11  GLN GLN G . n 
D 4 5   ALA 5   12  12  ALA ALA G . n 
D 4 6   ARG 6   13  13  ARG ARG G . n 
D 4 7   LYS 7   14  14  LYS LYS G . n 
D 4 8   LEU 8   15  15  LEU LEU G . n 
D 4 9   VAL 9   16  16  VAL VAL G . n 
D 4 10  GLU 10  17  17  GLU GLU G . n 
D 4 11  GLN 11  18  18  GLN GLN G . n 
D 4 12  LEU 12  19  19  LEU LEU G . n 
D 4 13  LYS 13  20  20  LYS LYS G . n 
D 4 14  MET 14  21  21  MET MET G . n 
D 4 15  GLU 15  22  22  GLU GLU G . n 
D 4 16  ALA 16  23  23  ALA ALA G . n 
D 4 17  ASN 17  24  24  ASN ASN G . n 
D 4 18  ILE 18  25  25  ILE ILE G . n 
D 4 19  ASP 19  26  26  ASP ASP G . n 
D 4 20  ARG 20  27  27  ARG ARG G . n 
D 4 21  ILE 21  28  28  ILE ILE G . n 
D 4 22  LYS 22  29  29  LYS LYS G . n 
D 4 23  VAL 23  30  30  VAL VAL G . n 
D 4 24  SER 24  31  31  SER SER G . n 
D 4 25  LYS 25  32  32  LYS LYS G . n 
D 4 26  ALA 26  33  33  ALA ALA G . n 
D 4 27  ALA 27  34  34  ALA ALA G . n 
D 4 28  ALA 28  35  35  ALA ALA G . n 
D 4 29  ASP 29  36  36  ASP ASP G . n 
D 4 30  LEU 30  37  37  LEU LEU G . n 
D 4 31  MET 31  38  38  MET MET G . n 
D 4 32  ALA 32  39  39  ALA ALA G . n 
D 4 33  TYR 33  40  40  TYR TYR G . n 
D 4 34  CYS 34  41  41  CYS CYS G . n 
D 4 35  GLU 35  42  42  GLU GLU G . n 
D 4 36  ALA 36  43  43  ALA ALA G . n 
D 4 37  HIS 37  44  44  HIS HIS G . n 
D 4 38  ALA 38  45  45  ALA ALA G . n 
D 4 39  LYS 39  46  46  LYS LYS G . n 
D 4 40  GLU 40  47  47  GLU GLU G . n 
D 4 41  ASP 41  48  48  ASP ASP G . n 
D 4 42  PRO 42  49  49  PRO PRO G . n 
D 4 43  LEU 43  50  50  LEU LEU G . n 
D 4 44  LEU 44  51  51  LEU LEU G . n 
D 4 45  THR 45  52  52  THR THR G . n 
D 4 46  PRO 46  53  53  PRO PRO G . n 
D 4 47  VAL 47  54  54  VAL VAL G . n 
D 4 48  PRO 48  55  55  PRO PRO G . n 
D 4 49  ALA 49  56  56  ALA ALA G . n 
D 4 50  SER 50  57  57  SER SER G . n 
D 4 51  GLU 51  58  58  GLU GLU G . n 
D 4 52  ASN 52  59  59  ASN ASN G . n 
D 4 53  PRO 53  60  60  PRO PRO G . n 
D 4 54  PHE 54  61  61  PHE PHE G . n 
D 4 55  ARG 55  62  62  ARG ARG G . n 
D 4 56  GLU 56  63  63  GLU GLU G . n 
E 5 1   ASP 1   1   1   ASP ASP S . n 
E 5 2   VAL 2   2   2   VAL VAL S . n 
E 5 3   GLN 3   3   3   GLN GLN S . n 
E 5 4   LEU 4   4   4   LEU LEU S . n 
E 5 5   VAL 5   5   5   VAL VAL S . n 
E 5 6   GLU 6   6   6   GLU GLU S . n 
E 5 7   SER 7   7   7   SER SER S . n 
E 5 8   GLY 8   8   8   GLY GLY S . n 
E 5 9   GLY 9   9   9   GLY GLY S . n 
E 5 10  GLY 10  10  10  GLY GLY S . n 
E 5 11  LEU 11  11  11  LEU LEU S . n 
E 5 12  VAL 12  12  12  VAL VAL S . n 
E 5 13  GLN 13  13  13  GLN GLN S . n 
E 5 14  PRO 14  14  14  PRO PRO S . n 
E 5 15  GLY 15  15  15  GLY GLY S . n 
E 5 16  GLY 16  16  16  GLY GLY S . n 
E 5 17  SER 17  17  17  SER SER S . n 
E 5 18  ARG 18  18  18  ARG ARG S . n 
E 5 19  LYS 19  19  19  LYS LYS S . n 
E 5 20  LEU 20  20  20  LEU LEU S . n 
E 5 21  SER 21  21  21  SER SER S . n 
E 5 22  CYS 22  22  22  CYS CYS S . n 
E 5 23  SER 23  23  23  SER SER S . n 
E 5 24  ALA 24  24  24  ALA ALA S . n 
E 5 25  SER 25  25  25  SER SER S . n 
E 5 26  GLY 26  26  26  GLY GLY S . n 
E 5 27  PHE 27  27  27  PHE PHE S . n 
E 5 28  ALA 28  28  28  ALA ALA S . n 
E 5 29  PHE 29  29  29  PHE PHE S . n 
E 5 30  SER 30  30  30  SER SER S . n 
E 5 31  SER 31  31  31  SER SER S . n 
E 5 32  PHE 32  32  32  PHE PHE S . n 
E 5 33  GLY 33  33  33  GLY GLY S . n 
E 5 34  MET 34  34  34  MET MET S . n 
E 5 35  HIS 35  35  35  HIS HIS S . n 
E 5 36  TRP 36  36  36  TRP TRP S . n 
E 5 37  VAL 37  37  37  VAL VAL S . n 
E 5 38  ARG 38  38  38  ARG ARG S . n 
E 5 39  GLN 39  39  39  GLN GLN S . n 
E 5 40  ALA 40  40  40  ALA ALA S . n 
E 5 41  PRO 41  41  41  PRO PRO S . n 
E 5 42  GLU 42  42  42  GLU GLU S . n 
E 5 43  LYS 43  43  43  LYS LYS S . n 
E 5 44  GLY 44  44  44  GLY GLY S . n 
E 5 45  LEU 45  45  45  LEU LEU S . n 
E 5 46  GLU 46  46  46  GLU GLU S . n 
E 5 47  TRP 47  47  47  TRP TRP S . n 
E 5 48  VAL 48  48  48  VAL VAL S . n 
E 5 49  ALA 49  49  49  ALA ALA S . n 
E 5 50  TYR 50  50  50  TYR TYR S . n 
E 5 51  ILE 51  51  51  ILE ILE S . n 
E 5 52  SER 52  52  52  SER SER S . n 
E 5 53  SER 53  53  53  SER SER S . n 
E 5 54  GLY 54  54  54  GLY GLY S . n 
E 5 55  SER 55  55  55  SER SER S . n 
E 5 56  GLY 56  56  56  GLY GLY S . n 
E 5 57  THR 57  57  57  THR THR S . n 
E 5 58  ILE 58  58  58  ILE ILE S . n 
E 5 59  TYR 59  59  59  TYR TYR S . n 
E 5 60  TYR 60  60  60  TYR TYR S . n 
E 5 61  ALA 61  61  61  ALA ALA S . n 
E 5 62  ASP 62  62  62  ASP ASP S . n 
E 5 63  THR 63  63  63  THR THR S . n 
E 5 64  VAL 64  64  64  VAL VAL S . n 
E 5 65  LYS 65  65  65  LYS LYS S . n 
E 5 66  GLY 66  66  66  GLY GLY S . n 
E 5 67  ARG 67  67  67  ARG ARG S . n 
E 5 68  PHE 68  68  68  PHE PHE S . n 
E 5 69  THR 69  69  69  THR THR S . n 
E 5 70  ILE 70  70  70  ILE ILE S . n 
E 5 71  SER 71  71  71  SER SER S . n 
E 5 72  ARG 72  72  72  ARG ARG S . n 
E 5 73  ASP 73  73  73  ASP ASP S . n 
E 5 74  ASP 74  74  74  ASP ASP S . n 
E 5 75  PRO 75  75  75  PRO PRO S . n 
E 5 76  LYS 76  76  76  LYS LYS S . n 
E 5 77  ASN 77  77  77  ASN ASN S . n 
E 5 78  THR 78  78  78  THR THR S . n 
E 5 79  LEU 79  79  79  LEU LEU S . n 
E 5 80  PHE 80  80  80  PHE PHE S . n 
E 5 81  LEU 81  81  81  LEU LEU S . n 
E 5 82  GLN 82  82  82  GLN GLN S . n 
E 5 83  MET 83  83  83  MET MET S . n 
E 5 84  THR 84  84  84  THR THR S . n 
E 5 85  SER 85  85  85  SER SER S . n 
E 5 86  LEU 86  86  86  LEU LEU S . n 
E 5 87  ARG 87  87  87  ARG ARG S . n 
E 5 88  SER 88  88  88  SER SER S . n 
E 5 89  GLU 89  89  89  GLU GLU S . n 
E 5 90  ASP 90  90  90  ASP ASP S . n 
E 5 91  THR 91  91  91  THR THR S . n 
E 5 92  ALA 92  92  92  ALA ALA S . n 
E 5 93  MET 93  93  93  MET MET S . n 
E 5 94  TYR 94  94  94  TYR TYR S . n 
E 5 95  TYR 95  95  95  TYR TYR S . n 
E 5 96  CYS 96  96  96  CYS CYS S . n 
E 5 97  VAL 97  97  97  VAL VAL S . n 
E 5 98  ARG 98  98  98  ARG ARG S . n 
E 5 99  SER 99  99  99  SER SER S . n 
E 5 100 ILE 100 100 100 ILE ILE S . n 
E 5 101 TYR 101 101 101 TYR TYR S . n 
E 5 102 TYR 102 102 102 TYR TYR S . n 
E 5 103 TYR 103 103 103 TYR TYR S . n 
E 5 104 GLY 104 104 104 GLY GLY S . n 
E 5 105 SER 105 105 105 SER SER S . n 
E 5 106 SER 106 106 106 SER SER S . n 
E 5 107 PRO 107 107 107 PRO PRO S . n 
E 5 108 PHE 108 108 108 PHE PHE S . n 
E 5 109 ASP 109 109 109 ASP ASP S . n 
E 5 110 PHE 110 110 110 PHE PHE S . n 
E 5 111 TRP 111 111 111 TRP TRP S . n 
E 5 112 GLY 112 112 112 GLY GLY S . n 
E 5 113 GLN 113 113 113 GLN GLN S . n 
E 5 114 GLY 114 114 114 GLY GLY S . n 
E 5 115 THR 115 115 115 THR THR S . n 
E 5 116 THR 116 116 116 THR THR S . n 
E 5 117 LEU 117 117 117 LEU LEU S . n 
E 5 118 THR 118 118 118 THR THR S . n 
E 5 119 VAL 119 119 119 VAL VAL S . n 
E 5 120 SER 120 120 120 SER SER S . n 
E 5 121 SER 121 121 121 SER SER S . n 
E 5 122 GLY 122 121 ?   ?   ?   S A n 
E 5 123 GLY 123 121 ?   ?   ?   S B n 
E 5 124 GLY 124 121 ?   ?   ?   S C n 
E 5 125 GLY 125 121 ?   ?   ?   S D n 
E 5 126 SER 126 121 ?   ?   ?   S E n 
E 5 127 GLY 127 121 ?   ?   ?   S F n 
E 5 128 GLY 128 121 ?   ?   ?   S G n 
E 5 129 GLY 129 121 ?   ?   ?   S H n 
E 5 130 GLY 130 121 ?   ?   ?   S I n 
E 5 131 SER 131 121 ?   ?   ?   S J n 
E 5 132 GLY 132 121 ?   ?   ?   S K n 
E 5 133 GLY 133 121 ?   ?   ?   S L n 
E 5 134 GLY 134 121 ?   ?   ?   S M n 
E 5 135 GLY 135 121 ?   ?   ?   S N n 
E 5 136 SER 136 121 ?   ?   ?   S O n 
E 5 137 SER 137 124 124 SER SER S . n 
E 5 138 ASP 138 125 125 ASP ASP S . n 
E 5 139 ILE 139 126 126 ILE ILE S . n 
E 5 140 VAL 140 127 127 VAL VAL S . n 
E 5 141 MET 141 128 128 MET MET S . n 
E 5 142 THR 142 129 129 THR THR S . n 
E 5 143 GLN 143 130 130 GLN GLN S . n 
E 5 144 ALA 144 131 131 ALA ALA S . n 
E 5 145 THR 145 132 132 THR THR S . n 
E 5 146 SER 146 133 133 SER SER S . n 
E 5 147 SER 147 134 134 SER SER S . n 
E 5 148 VAL 148 135 135 VAL VAL S . n 
E 5 149 PRO 149 136 136 PRO PRO S . n 
E 5 150 VAL 150 137 137 VAL VAL S . n 
E 5 151 THR 151 138 138 THR THR S . n 
E 5 152 PRO 152 139 139 PRO PRO S . n 
E 5 153 GLY 153 140 140 GLY GLY S . n 
E 5 154 GLU 154 141 141 GLU GLU S . n 
E 5 155 SER 155 142 142 SER SER S . n 
E 5 156 VAL 156 143 143 VAL VAL S . n 
E 5 157 SER 157 144 144 SER SER S . n 
E 5 158 ILE 158 145 145 ILE ILE S . n 
E 5 159 SER 159 146 146 SER SER S . n 
E 5 160 CYS 160 147 147 CYS CYS S . n 
E 5 161 ARG 161 148 148 ARG ARG S . n 
E 5 162 SER 162 149 149 SER SER S . n 
E 5 163 SER 163 150 150 SER SER S . n 
E 5 164 LYS 164 151 151 LYS LYS S . n 
E 5 165 SER 165 152 152 SER SER S . n 
E 5 166 LEU 166 153 153 LEU LEU S . n 
E 5 167 LEU 167 154 154 LEU LEU S . n 
E 5 168 HIS 168 155 155 HIS HIS S . n 
E 5 169 SER 169 156 156 SER SER S . n 
E 5 170 ASN 170 157 157 ASN ASN S . n 
E 5 171 GLY 171 158 158 GLY GLY S . n 
E 5 172 ASN 172 159 159 ASN ASN S . n 
E 5 173 THR 173 160 160 THR THR S . n 
E 5 174 TYR 174 161 161 TYR TYR S . n 
E 5 175 LEU 175 162 162 LEU LEU S . n 
E 5 176 TYR 176 163 163 TYR TYR S . n 
E 5 177 TRP 177 164 164 TRP TRP S . n 
E 5 178 PHE 178 165 165 PHE PHE S . n 
E 5 179 LEU 179 166 166 LEU LEU S . n 
E 5 180 GLN 180 167 167 GLN GLN S . n 
E 5 181 ARG 181 168 168 ARG ARG S . n 
E 5 182 PRO 182 169 169 PRO PRO S . n 
E 5 183 GLY 183 170 170 GLY GLY S . n 
E 5 184 GLN 184 171 171 GLN GLN S . n 
E 5 185 SER 185 172 172 SER SER S . n 
E 5 186 PRO 186 173 173 PRO PRO S . n 
E 5 187 GLN 187 174 174 GLN GLN S . n 
E 5 188 LEU 188 175 175 LEU LEU S . n 
E 5 189 LEU 189 176 176 LEU LEU S . n 
E 5 190 ILE 190 177 177 ILE ILE S . n 
E 5 191 TYR 191 178 178 TYR TYR S . n 
E 5 192 ARG 192 179 179 ARG ARG S . n 
E 5 193 MET 193 180 180 MET MET S . n 
E 5 194 SER 194 181 181 SER SER S . n 
E 5 195 ASN 195 182 182 ASN ASN S . n 
E 5 196 LEU 196 183 183 LEU LEU S . n 
E 5 197 ALA 197 184 184 ALA ALA S . n 
E 5 198 SER 198 185 185 SER SER S . n 
E 5 199 GLY 199 186 186 GLY GLY S . n 
E 5 200 VAL 200 187 187 VAL VAL S . n 
E 5 201 PRO 201 188 188 PRO PRO S . n 
E 5 202 ASP 202 189 189 ASP ASP S . n 
E 5 203 ARG 203 190 190 ARG ARG S . n 
E 5 204 PHE 204 191 191 PHE PHE S . n 
E 5 205 SER 205 192 192 SER SER S . n 
E 5 206 GLY 206 193 193 GLY GLY S . n 
E 5 207 SER 207 194 194 SER SER S . n 
E 5 208 GLY 208 195 195 GLY GLY S . n 
E 5 209 SER 209 196 196 SER SER S . n 
E 5 210 GLY 210 197 197 GLY GLY S . n 
E 5 211 THR 211 198 198 THR THR S . n 
E 5 212 ALA 212 199 199 ALA ALA S . n 
E 5 213 PHE 213 200 200 PHE PHE S . n 
E 5 214 THR 214 201 201 THR THR S . n 
E 5 215 LEU 215 202 202 LEU LEU S . n 
E 5 216 THR 216 203 203 THR THR S . n 
E 5 217 ILE 217 204 204 ILE ILE S . n 
E 5 218 SER 218 205 205 SER SER S . n 
E 5 219 ARG 219 206 206 ARG ARG S . n 
E 5 220 LEU 220 207 207 LEU LEU S . n 
E 5 221 GLU 221 208 208 GLU GLU S . n 
E 5 222 ALA 222 209 209 ALA ALA S . n 
E 5 223 GLU 223 210 210 GLU GLU S . n 
E 5 224 ASP 224 211 211 ASP ASP S . n 
E 5 225 VAL 225 212 212 VAL VAL S . n 
E 5 226 GLY 226 213 213 GLY GLY S . n 
E 5 227 VAL 227 214 214 VAL VAL S . n 
E 5 228 TYR 228 215 215 TYR TYR S . n 
E 5 229 TYR 229 216 216 TYR TYR S . n 
E 5 230 CYS 230 217 217 CYS CYS S . n 
E 5 231 MET 231 218 218 MET MET S . n 
E 5 232 GLN 232 219 219 GLN GLN S . n 
E 5 233 HIS 233 220 220 HIS HIS S . n 
E 5 234 LEU 234 221 221 LEU LEU S . n 
E 5 235 GLU 235 222 222 GLU GLU S . n 
E 5 236 TYR 236 223 223 TYR TYR S . n 
E 5 237 PRO 237 224 224 PRO PRO S . n 
E 5 238 LEU 238 225 225 LEU LEU S . n 
E 5 239 THR 239 226 226 THR THR S . n 
E 5 240 PHE 240 227 227 PHE PHE S . n 
E 5 241 GLY 241 228 228 GLY GLY S . n 
E 5 242 ALA 242 229 229 ALA ALA S . n 
E 5 243 GLY 243 230 230 GLY GLY S . n 
E 5 244 THR 244 231 231 THR THR S . n 
E 5 245 LYS 245 232 232 LYS LYS S . n 
E 5 246 LEU 246 233 233 LEU LEU S . n 
E 5 247 GLU 247 234 234 GLU GLU S . n 
E 5 248 LEU 248 235 235 LEU LEU S . n 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          XOT 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      XOT 
_pdbx_nonpoly_scheme.auth_mon_id     MK1 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9IZC 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9IZC 
_struct.title                        'Cryo-EM structure of human HCAR2-Gi complex with MK1903' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9IZC 
_struct_keywords.text            'complex, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP HCAR2_HUMAN Q8TDS4 ? 1 
;DHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNY
VRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKM
PIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPS
VVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF
;
8 
2 UNP GBB1_HUMAN  P62873 ? 2 
;LDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWD
SYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGD
TTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT
GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDD
GMAVATGSWDSFLKIWN
;
4 
3 UNP GNAI1_HUMAN P63096 ? 3 
;TLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQSIIA
IIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIA
QPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRM
HESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTHF
TCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
4 
4 UNP GBG2_HUMAN  P59768 ? 4 SIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFRE 8 
5 PDB 9IZC        9IZC   ? 5 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9IZC A 1 ? 294 ? Q8TDS4 8 ? 301 ? 8 301 
2 2 9IZC B 1 ? 337 ? P62873 4 ? 340 ? 4 340 
3 3 9IZC C 1 ? 351 ? P63096 4 ? 354 ? 4 354 
4 4 9IZC G 1 ? 56  ? P59768 8 ? 63  ? 8 63  
5 5 9IZC S 1 ? 248 ? 9IZC   1 ? 235 ? 1 235 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9IZC ALA C 200 ? UNP P63096 GLY 203 'engineered mutation' 203 1 
3 9IZC SER C 323 ? UNP P63096 ALA 326 'engineered mutation' 326 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 VAL A 22  ? HIS A 48  ? VAL A 29  HIS A 55  1 ? 27 
HELX_P HELX_P2  AA2 LYS A 53  ? CYS A 72  ? LYS A 60  CYS A 79  1 ? 20 
HELX_P HELX_P3  AA3 CYS A 72  ? ARG A 82  ? CYS A 79  ARG A 89  1 ? 11 
HELX_P HELX_P4  AA4 GLY A 89  ? HIS A 124 ? GLY A 96  HIS A 131 1 ? 36 
HELX_P HELX_P5  AA5 HIS A 127 ? ILE A 132 ? HIS A 134 ILE A 139 5 ? 6  
HELX_P HELX_P6  AA6 SER A 133 ? LEU A 151 ? SER A 140 LEU A 158 1 ? 19 
HELX_P HELX_P7  AA7 THR A 152 ? LEU A 156 ? THR A 159 LEU A 163 5 ? 5  
HELX_P HELX_P8  AA8 GLN A 180 ? ARG A 211 ? GLN A 187 ARG A 218 1 ? 32 
HELX_P HELX_P9  AA9 HIS A 216 ? SER A 254 ? HIS A 223 SER A 261 1 ? 39 
HELX_P HELX_P10 AB1 TYR A 262 ? TYR A 288 ? TYR A 269 TYR A 295 1 ? 27 
HELX_P HELX_P11 AB2 ASP B 2   ? ALA B 23  ? ASP B 5   ALA B 26  1 ? 22 
HELX_P HELX_P12 AB3 THR B 26  ? THR B 31  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P13 AB4 SER C 3   ? ALA C 28  ? SER C 6   ALA C 31  1 ? 26 
HELX_P HELX_P14 AB5 GLY C 42  ? LYS C 48  ? GLY C 45  LYS C 51  1 ? 7  
HELX_P HELX_P15 AB6 GLU C 204 ? ILE C 209 ? GLU C 207 ILE C 212 1 ? 6  
HELX_P HELX_P16 AB7 HIS C 210 ? GLU C 213 ? HIS C 213 GLU C 216 5 ? 4  
HELX_P HELX_P17 AB8 ARG C 239 ? ASN C 252 ? ARG C 242 ASN C 255 1 ? 14 
HELX_P HELX_P18 AB9 LYS C 267 ? SER C 278 ? LYS C 270 SER C 281 1 ? 12 
HELX_P HELX_P19 AC1 THR C 292 ? ASP C 306 ? THR C 295 ASP C 309 1 ? 15 
HELX_P HELX_P20 AC2 THR C 326 ? CYS C 348 ? THR C 329 CYS C 351 1 ? 23 
HELX_P HELX_P21 AC3 ILE D 2   ? ASN D 17  ? ILE G 9   ASN G 24  1 ? 16 
HELX_P HELX_P22 AC4 LYS D 22  ? ALA D 38  ? LYS G 29  ALA G 45  1 ? 17 
HELX_P HELX_P23 AC5 LYS D 39  ? ASP D 41  ? LYS G 46  ASP G 48  5 ? 3  
HELX_P HELX_P24 AC6 ALA E 28  ? PHE E 32  ? ALA S 28  PHE S 32  5 ? 5  
HELX_P HELX_P25 AC7 ASP E 74  ? LYS E 76  ? ASP S 74  LYS S 76  5 ? 3  
HELX_P HELX_P26 AC8 ARG E 87  ? THR E 91  ? ARG S 87  THR S 91  5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 11  SG ? ? ? 1_555 A CYS 176 SG ? ? A CYS 18  A CYS 183 1_555 ? ? ? ? ? ? ? 2.049 ? ? 
disulf2 disulf ? ? A CYS 12  SG ? ? ? 1_555 A CYS 259 SG ? ? A CYS 19  A CYS 266 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf3 disulf ? ? A CYS 93  SG ? ? ? 1_555 A CYS 170 SG ? ? A CYS 100 A CYS 177 1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf4 disulf ? ? E CYS 22  SG ? ? ? 1_555 E CYS 96  SG ? ? S CYS 22  S CYS 96  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf5 disulf ? ? E CYS 160 SG ? ? ? 1_555 E CYS 230 SG ? ? S CYS 147 S CYS 217 1_555 ? ? ? ? ? ? ? 2.037 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 11  ? CYS A 176 ? CYS A 18  ? 1_555 CYS A 183 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 12  ? CYS A 259 ? CYS A 19  ? 1_555 CYS A 266 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS A 93  ? CYS A 170 ? CYS A 100 ? 1_555 CYS A 177 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS E 22  ? CYS E 96  ? CYS S 22  ? 1_555 CYS S 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS E 160 ? CYS E 230 ? CYS S 147 ? 1_555 CYS S 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           236 
_struct_mon_prot_cis.label_asym_id          E 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            223 
_struct_mon_prot_cis.auth_asym_id           S 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    237 
_struct_mon_prot_cis.pdbx_label_asym_id_2   E 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     224 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    S 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       1.65 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 6 ? 
AB4 ? 5 ? 
AB5 ? 4 ? 
AB6 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? parallel      
AB1 3 4 ? parallel      
AB1 4 5 ? parallel      
AB1 5 6 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB6 4 5 ? anti-parallel 
AB6 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 3   ? LEU A 4   ? PHE A 10  LEU A 11  
AA1 2 CYS A 11  ? CYS A 12  ? CYS A 18  CYS A 19  
AA2 1 ILE A 162 ? GLN A 163 ? ILE A 169 GLN A 170 
AA2 2 ASN A 168 ? LEU A 169 ? ASN A 175 LEU A 176 
AA3 1 THR B 44  ? LEU B 48  ? THR B 47  LEU B 51  
AA3 2 LEU B 333 ? TRP B 336 ? LEU B 336 TRP B 339 
AA3 3 VAL B 324 ? SER B 328 ? VAL B 327 SER B 331 
AA3 4 VAL B 312 ? VAL B 317 ? VAL B 315 VAL B 320 
AA4 1 ILE B 55  ? TRP B 60  ? ILE B 58  TRP B 63  
AA4 2 LEU B 66  ? SER B 71  ? LEU B 69  SER B 74  
AA4 3 LYS B 75  ? ASP B 80  ? LYS B 78  ASP B 83  
AA4 4 ASN B 85  ? PRO B 91  ? ASN B 88  PRO B 94  
AA5 1 VAL B 97  ? TYR B 102 ? VAL B 100 TYR B 105 
AA5 2 TYR B 108 ? GLY B 113 ? TYR B 111 GLY B 116 
AA5 3 ILE B 117 ? ASN B 122 ? ILE B 120 ASN B 125 
AA5 4 ARG B 131 ? ALA B 137 ? ARG B 134 ALA B 140 
AA6 1 LEU B 143 ? PHE B 148 ? LEU B 146 PHE B 151 
AA6 2 GLN B 153 ? SER B 158 ? GLN B 156 SER B 161 
AA6 3 CYS B 163 ? ASP B 167 ? CYS B 166 ASP B 170 
AA6 4 GLN B 172 ? PHE B 177 ? GLN B 175 PHE B 180 
AA7 1 VAL B 184 ? LEU B 189 ? VAL B 187 LEU B 192 
AA7 2 LEU B 195 ? ALA B 200 ? LEU B 198 ALA B 203 
AA7 3 ALA B 205 ? ASP B 209 ? ALA B 208 ASP B 212 
AA7 4 CYS B 215 ? PHE B 219 ? CYS B 218 PHE B 222 
AA8 1 ILE B 226 ? PHE B 231 ? ILE B 229 PHE B 234 
AA8 2 ALA B 237 ? SER B 242 ? ALA B 240 SER B 245 
AA8 3 CYS B 247 ? ASP B 251 ? CYS B 250 ASP B 254 
AA8 4 GLN B 256 ? TYR B 261 ? GLN B 259 TYR B 264 
AA9 1 ILE B 270 ? PHE B 275 ? ILE B 273 PHE B 278 
AA9 2 LEU B 281 ? TYR B 286 ? LEU B 284 TYR B 289 
AA9 3 CYS B 291 ? ASP B 295 ? CYS B 294 ASP B 298 
AA9 4 ARG B 301 ? LEU B 305 ? ARG B 304 LEU B 308 
AB1 1 VAL C 182 ? PHE C 188 ? VAL C 185 PHE C 191 
AB1 2 LEU C 191 ? ASP C 197 ? LEU C 194 ASP C 200 
AB1 3 GLU C 30  ? LEU C 36  ? GLU C 33  LEU C 39  
AB1 4 ALA C 217 ? ALA C 223 ? ALA C 220 ALA C 226 
AB1 5 SER C 260 ? ASN C 266 ? SER C 263 ASN C 269 
AB1 6 ILE C 316 ? HIS C 319 ? ILE C 319 HIS C 322 
AB2 1 GLN E 3   ? SER E 7   ? GLN S 3   SER S 7   
AB2 2 LYS E 19  ? SER E 25  ? LYS S 19  SER S 25  
AB2 3 THR E 78  ? MET E 83  ? THR S 78  MET S 83  
AB2 4 PHE E 68  ? ASP E 73  ? PHE S 68  ASP S 73  
AB3 1 GLY E 10  ? VAL E 12  ? GLY S 10  VAL S 12  
AB3 2 THR E 115 ? VAL E 119 ? THR S 115 VAL S 119 
AB3 3 ALA E 92  ? TYR E 95  ? ALA S 92  TYR S 95  
AB3 4 GLY E 33  ? GLN E 39  ? GLY S 33  GLN S 39  
AB3 5 LEU E 45  ? ILE E 51  ? LEU S 45  ILE S 51  
AB3 6 ILE E 58  ? TYR E 60  ? ILE S 58  TYR S 60  
AB4 1 GLY E 10  ? VAL E 12  ? GLY S 10  VAL S 12  
AB4 2 THR E 115 ? VAL E 119 ? THR S 115 VAL S 119 
AB4 3 ALA E 92  ? TYR E 95  ? ALA S 92  TYR S 95  
AB4 4 GLY E 33  ? GLN E 39  ? GLY S 33  GLN S 39  
AB4 5 ARG E 98  ? SER E 99  ? ARG S 98  SER S 99  
AB5 1 MET E 141 ? THR E 142 ? MET S 128 THR S 129 
AB5 2 VAL E 156 ? SER E 162 ? VAL S 143 SER S 149 
AB5 3 ALA E 212 ? ILE E 217 ? ALA S 199 ILE S 204 
AB5 4 PHE E 204 ? SER E 209 ? PHE S 191 SER S 196 
AB6 1 SER E 147 ? PRO E 149 ? SER S 134 PRO S 136 
AB6 2 THR E 244 ? GLU E 247 ? THR S 231 GLU S 234 
AB6 3 GLY E 226 ? GLN E 232 ? GLY S 213 GLN S 219 
AB6 4 LEU E 175 ? GLN E 180 ? LEU S 162 GLN S 167 
AB6 5 PRO E 186 ? TYR E 191 ? PRO S 173 TYR S 178 
AB6 6 ASN E 195 ? LEU E 196 ? ASN S 182 LEU S 183 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LEU A 4   ? N LEU A 11  O CYS A 11  ? O CYS A 18  
AA2 1 2 N ILE A 162 ? N ILE A 169 O LEU A 169 ? O LEU A 176 
AA3 1 2 N ARG B 45  ? N ARG B 48  O ILE B 335 ? O ILE B 338 
AA3 2 3 O TRP B 336 ? O TRP B 339 N VAL B 324 ? N VAL B 327 
AA3 3 4 O ALA B 325 ? O ALA B 328 N GLY B 316 ? N GLY B 319 
AA4 1 2 N ALA B 57  ? N ALA B 60  O ALA B 70  ? O ALA B 73  
AA4 2 3 N LEU B 67  ? N LEU B 70  O TRP B 79  ? O TRP B 82  
AA4 3 4 N LEU B 76  ? N LEU B 79  O ILE B 90  ? O ILE B 93  
AA5 1 2 N ALA B 101 ? N ALA B 104 O ALA B 110 ? O ALA B 113 
AA5 2 3 N VAL B 109 ? N VAL B 112 O TYR B 121 ? O TYR B 124 
AA5 3 4 N ILE B 120 ? N ILE B 123 O SER B 133 ? O SER B 136 
AA6 1 2 N CYS B 145 ? N CYS B 148 O SER B 157 ? O SER B 160 
AA6 2 3 N THR B 156 ? N THR B 159 O ALA B 164 ? O ALA B 167 
AA6 3 4 N CYS B 163 ? N CYS B 166 O PHE B 177 ? O PHE B 180 
AA7 1 2 N SER B 188 ? N SER B 191 O VAL B 197 ? O VAL B 200 
AA7 2 3 N PHE B 196 ? N PHE B 199 O TRP B 208 ? O TRP B 211 
AA7 3 4 N ALA B 205 ? N ALA B 208 O PHE B 219 ? O PHE B 222 
AA8 1 2 N CYS B 230 ? N CYS B 233 O ALA B 239 ? O ALA B 242 
AA8 2 3 N PHE B 238 ? N PHE B 241 O PHE B 250 ? O PHE B 253 
AA8 3 4 N CYS B 247 ? N CYS B 250 O TYR B 261 ? O TYR B 264 
AA9 1 2 N THR B 271 ? N THR B 274 O GLY B 285 ? O GLY B 288 
AA9 2 3 N LEU B 282 ? N LEU B 285 O TRP B 294 ? O TRP B 297 
AA9 3 4 N CYS B 291 ? N CYS B 294 O LEU B 305 ? O LEU B 308 
AB1 1 2 N THR C 184 ? N THR C 187 O MET C 195 ? O MET C 198 
AB1 2 3 O LYS C 194 ? O LYS C 197 N LEU C 33  ? N LEU C 36  
AB1 3 4 N LEU C 36  ? N LEU C 39  O ILE C 219 ? O ILE C 222 
AB1 4 5 N ILE C 218 ? N ILE C 221 O ILE C 262 ? O ILE C 265 
AB1 5 6 N LEU C 263 ? N LEU C 266 O TYR C 317 ? O TYR C 320 
AB2 1 2 N SER E 7   ? N SER S 7   O SER E 21  ? O SER S 21  
AB2 2 3 N CYS E 22  ? N CYS S 22  O LEU E 79  ? O LEU S 79  
AB2 3 4 O GLN E 82  ? O GLN S 82  N THR E 69  ? N THR S 69  
AB3 1 2 N VAL E 12  ? N VAL S 12  O THR E 118 ? O THR S 118 
AB3 2 3 O LEU E 117 ? O LEU S 117 N ALA E 92  ? N ALA S 92  
AB3 3 4 O TYR E 95  ? O TYR S 95  N VAL E 37  ? N VAL S 37  
AB3 4 5 N TRP E 36  ? N TRP S 36  O VAL E 48  ? O VAL S 48  
AB3 5 6 N TYR E 50  ? N TYR S 50  O TYR E 59  ? O TYR S 59  
AB4 1 2 N VAL E 12  ? N VAL S 12  O THR E 118 ? O THR S 118 
AB4 2 3 O LEU E 117 ? O LEU S 117 N ALA E 92  ? N ALA S 92  
AB4 3 4 O TYR E 95  ? O TYR S 95  N VAL E 37  ? N VAL S 37  
AB4 4 5 N GLY E 33  ? N GLY S 33  O SER E 99  ? O SER S 99  
AB5 1 2 N THR E 142 ? N THR S 129 O ARG E 161 ? O ARG S 148 
AB5 2 3 N ILE E 158 ? N ILE S 145 O LEU E 215 ? O LEU S 202 
AB5 3 4 O THR E 214 ? O THR S 201 N SER E 207 ? N SER S 194 
AB6 1 2 N VAL E 148 ? N VAL S 135 O LYS E 245 ? O LYS S 232 
AB6 2 3 O THR E 244 ? O THR S 231 N TYR E 228 ? N TYR S 215 
AB6 3 4 O MET E 231 ? O MET S 218 N TYR E 176 ? N TYR S 163 
AB6 4 5 N TRP E 177 ? N TRP S 164 O LEU E 189 ? O LEU S 176 
AB6 5 6 N TYR E 191 ? N TYR S 178 O ASN E 195 ? O ASN S 182 
# 
_pdbx_entry_details.entry_id                   9IZC 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OG  B SER 245 ? ? OD1 B ASP 247 ? ? 2.07 
2 1 O   A THR 155 ? ? OG1 A THR 159 ? ? 2.15 
3 1 O   B ILE 58  ? ? OG  B SER 316 ? ? 2.18 
4 1 OG1 B THR 274 ? ? O   B VAL 315 ? ? 2.18 
5 1 OE2 C GLU 8   ? ? OH  S TYR 163 ? ? 2.19 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             A 
_pdbx_validate_rmsd_angle.auth_comp_id_1             LEU 
_pdbx_validate_rmsd_angle.auth_seq_id_1              158 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_2             A 
_pdbx_validate_rmsd_angle.auth_comp_id_2             LEU 
_pdbx_validate_rmsd_angle.auth_seq_id_2              158 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CG 
_pdbx_validate_rmsd_angle.auth_asym_id_3             A 
_pdbx_validate_rmsd_angle.auth_comp_id_3             LEU 
_pdbx_validate_rmsd_angle.auth_seq_id_3              158 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                131.53 
_pdbx_validate_rmsd_angle.angle_target_value         115.30 
_pdbx_validate_rmsd_angle.angle_deviation            16.23 
_pdbx_validate_rmsd_angle.angle_standard_deviation   2.30 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 14  ? ? 44.34   27.04   
2  1 LYS A 15  ? ? -171.16 -173.81 
3  1 ASN A 17  ? ? 70.35   45.35   
4  1 ASP A 24  ? ? -78.29  -167.53 
5  1 ILE A 26  ? ? -96.00  -64.18  
6  1 LYS A 28  ? ? -142.27 -24.53  
7  1 ARG A 89  ? ? -95.79  34.90   
8  1 ARG A 90  ? ? 57.46   -125.96 
9  1 TRP A 91  ? ? -106.36 48.51   
10 1 CYS A 177 ? ? -91.83  52.61   
11 1 SER A 181 ? ? -118.85 -154.12 
12 1 THR A 185 ? ? -38.74  124.61  
13 1 THR B 196 ? ? 57.29   18.75   
14 1 ASP B 291 ? ? -68.74  5.24    
15 1 PHE B 292 ? ? 82.89   8.52    
16 1 GLU C 43  ? ? -66.15  0.47    
17 1 ARG C 205 ? ? -91.07  53.79   
18 1 ASN C 255 ? ? -95.00  57.50   
19 1 PHE C 259 ? ? -94.70  57.29   
20 1 TYR C 290 ? ? -160.45 118.21  
21 1 THR C 327 ? ? 39.54   -130.00 
22 1 ASP C 328 ? ? -124.70 -169.60 
23 1 ASN G 24  ? ? -93.81  59.08   
24 1 CYS S 96  ? ? -119.69 50.17   
25 1 ALA S 131 ? ? 50.74   -119.81 
26 1 MET S 180 ? ? 73.95   -11.50  
27 1 ALA S 209 ? ? -66.42  -178.65 
28 1 GLU S 234 ? ? -129.95 -169.97 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9IZC 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9IZC 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.68 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               439381 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.2 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Cryo-EM structure of human HCAR2-Gi complex with MK1903' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        9IZC 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             1400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
_em_imaging.objective_aperture              ? 
_em_imaging.microscope_serial_number        ? 
_em_imaging.microscope_version              ? 
# 
_em_vitrification.entry_id              9IZC 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          NITROGEN 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9IZC 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 C LYS 54  ? C LYS 51  
2   1 Y 1 C ILE 55  ? C ILE 52  
3   1 Y 1 C ILE 56  ? C ILE 53  
4   1 Y 1 C HIS 57  ? C HIS 54  
5   1 Y 1 C GLU 58  ? C GLU 55  
6   1 Y 1 C ALA 59  ? C ALA 56  
7   1 Y 1 C GLY 60  ? C GLY 57  
8   1 Y 1 C TYR 61  ? C TYR 58  
9   1 Y 1 C SER 62  ? C SER 59  
10  1 Y 1 C GLU 63  ? C GLU 60  
11  1 Y 1 C GLU 64  ? C GLU 61  
12  1 Y 1 C GLU 65  ? C GLU 62  
13  1 Y 1 C CYS 66  ? C CYS 63  
14  1 Y 1 C LYS 67  ? C LYS 64  
15  1 Y 1 C GLN 68  ? C GLN 65  
16  1 Y 1 C TYR 69  ? C TYR 66  
17  1 Y 1 C LYS 70  ? C LYS 67  
18  1 Y 1 C ALA 71  ? C ALA 68  
19  1 Y 1 C VAL 72  ? C VAL 69  
20  1 Y 1 C VAL 73  ? C VAL 70  
21  1 Y 1 C TYR 74  ? C TYR 71  
22  1 Y 1 C SER 75  ? C SER 72  
23  1 Y 1 C ASN 76  ? C ASN 73  
24  1 Y 1 C THR 77  ? C THR 74  
25  1 Y 1 C ILE 78  ? C ILE 75  
26  1 Y 1 C GLN 79  ? C GLN 76  
27  1 Y 1 C SER 80  ? C SER 77  
28  1 Y 1 C ILE 81  ? C ILE 78  
29  1 Y 1 C ILE 82  ? C ILE 79  
30  1 Y 1 C ALA 83  ? C ALA 80  
31  1 Y 1 C ILE 84  ? C ILE 81  
32  1 Y 1 C ILE 85  ? C ILE 82  
33  1 Y 1 C ARG 86  ? C ARG 83  
34  1 Y 1 C ALA 87  ? C ALA 84  
35  1 Y 1 C MET 88  ? C MET 85  
36  1 Y 1 C GLY 89  ? C GLY 86  
37  1 Y 1 C ARG 90  ? C ARG 87  
38  1 Y 1 C LEU 91  ? C LEU 88  
39  1 Y 1 C LYS 92  ? C LYS 89  
40  1 Y 1 C ILE 93  ? C ILE 90  
41  1 Y 1 C ASP 94  ? C ASP 91  
42  1 Y 1 C PHE 95  ? C PHE 92  
43  1 Y 1 C GLY 96  ? C GLY 93  
44  1 Y 1 C ASP 97  ? C ASP 94  
45  1 Y 1 C SER 98  ? C SER 95  
46  1 Y 1 C ALA 99  ? C ALA 96  
47  1 Y 1 C ARG 100 ? C ARG 97  
48  1 Y 1 C ALA 101 ? C ALA 98  
49  1 Y 1 C ASP 102 ? C ASP 99  
50  1 Y 1 C ASP 103 ? C ASP 100 
51  1 Y 1 C ALA 104 ? C ALA 101 
52  1 Y 1 C ARG 105 ? C ARG 102 
53  1 Y 1 C GLN 106 ? C GLN 103 
54  1 Y 1 C LEU 107 ? C LEU 104 
55  1 Y 1 C PHE 108 ? C PHE 105 
56  1 Y 1 C VAL 109 ? C VAL 106 
57  1 Y 1 C LEU 110 ? C LEU 107 
58  1 Y 1 C ALA 111 ? C ALA 108 
59  1 Y 1 C GLY 112 ? C GLY 109 
60  1 Y 1 C ALA 113 ? C ALA 110 
61  1 Y 1 C ALA 114 ? C ALA 111 
62  1 Y 1 C GLU 115 ? C GLU 112 
63  1 Y 1 C GLU 116 ? C GLU 113 
64  1 Y 1 C GLY 117 ? C GLY 114 
65  1 Y 1 C PHE 118 ? C PHE 115 
66  1 Y 1 C MET 119 ? C MET 116 
67  1 Y 1 C THR 120 ? C THR 117 
68  1 Y 1 C ALA 121 ? C ALA 118 
69  1 Y 1 C GLU 122 ? C GLU 119 
70  1 Y 1 C LEU 123 ? C LEU 120 
71  1 Y 1 C ALA 124 ? C ALA 121 
72  1 Y 1 C GLY 125 ? C GLY 122 
73  1 Y 1 C VAL 126 ? C VAL 123 
74  1 Y 1 C ILE 127 ? C ILE 124 
75  1 Y 1 C LYS 128 ? C LYS 125 
76  1 Y 1 C ARG 129 ? C ARG 126 
77  1 Y 1 C LEU 130 ? C LEU 127 
78  1 Y 1 C TRP 131 ? C TRP 128 
79  1 Y 1 C LYS 132 ? C LYS 129 
80  1 Y 1 C ASP 133 ? C ASP 130 
81  1 Y 1 C SER 134 ? C SER 131 
82  1 Y 1 C GLY 135 ? C GLY 132 
83  1 Y 1 C VAL 136 ? C VAL 133 
84  1 Y 1 C GLN 137 ? C GLN 134 
85  1 Y 1 C ALA 138 ? C ALA 135 
86  1 Y 1 C CYS 139 ? C CYS 136 
87  1 Y 1 C PHE 140 ? C PHE 137 
88  1 Y 1 C ASN 141 ? C ASN 138 
89  1 Y 1 C ARG 142 ? C ARG 139 
90  1 Y 1 C SER 143 ? C SER 140 
91  1 Y 1 C ARG 144 ? C ARG 141 
92  1 Y 1 C GLU 145 ? C GLU 142 
93  1 Y 1 C TYR 146 ? C TYR 143 
94  1 Y 1 C GLN 147 ? C GLN 144 
95  1 Y 1 C LEU 148 ? C LEU 145 
96  1 Y 1 C ASN 149 ? C ASN 146 
97  1 Y 1 C ASP 150 ? C ASP 147 
98  1 Y 1 C SER 151 ? C SER 148 
99  1 Y 1 C ALA 152 ? C ALA 149 
100 1 Y 1 C ALA 153 ? C ALA 150 
101 1 Y 1 C TYR 154 ? C TYR 151 
102 1 Y 1 C TYR 155 ? C TYR 152 
103 1 Y 1 C LEU 156 ? C LEU 153 
104 1 Y 1 C ASN 157 ? C ASN 154 
105 1 Y 1 C ASP 158 ? C ASP 155 
106 1 Y 1 C LEU 159 ? C LEU 156 
107 1 Y 1 C ASP 160 ? C ASP 157 
108 1 Y 1 C ARG 161 ? C ARG 158 
109 1 Y 1 C ILE 162 ? C ILE 159 
110 1 Y 1 C ALA 163 ? C ALA 160 
111 1 Y 1 C GLN 164 ? C GLN 161 
112 1 Y 1 C PRO 165 ? C PRO 162 
113 1 Y 1 C ASN 166 ? C ASN 163 
114 1 Y 1 C TYR 167 ? C TYR 164 
115 1 Y 1 C ILE 168 ? C ILE 165 
116 1 Y 1 C PRO 169 ? C PRO 166 
117 1 Y 1 C THR 170 ? C THR 167 
118 1 Y 1 C GLN 171 ? C GLN 168 
119 1 Y 1 C GLN 172 ? C GLN 169 
120 1 Y 1 C ASP 173 ? C ASP 170 
121 1 Y 1 C VAL 174 ? C VAL 171 
122 1 Y 1 C LEU 175 ? C LEU 172 
123 1 Y 1 C ARG 176 ? C ARG 173 
124 1 Y 1 C THR 177 ? C THR 174 
125 1 Y 1 C ARG 178 ? C ARG 175 
126 1 Y 1 C VAL 179 ? C VAL 176 
127 1 Y 1 C LYS 180 ? C LYS 177 
128 1 Y 1 C THR 181 ? C THR 178 
129 1 Y 1 C LEU 234 ? C LEU 231 
130 1 Y 1 C ALA 235 ? C ALA 232 
131 1 Y 1 C GLU 236 ? C GLU 233 
132 1 Y 1 C ASP 237 ? C ASP 234 
133 1 Y 1 C GLU 238 ? C GLU 235 
134 1 Y 1 C GLU 239 ? C GLU 236 
135 1 Y 1 C MET 240 ? C MET 237 
136 1 Y 1 S GLY 121 A E GLY 122 
137 1 Y 1 S GLY 121 B E GLY 123 
138 1 Y 1 S GLY 121 C E GLY 124 
139 1 Y 1 S GLY 121 D E GLY 125 
140 1 Y 1 S SER 121 E E SER 126 
141 1 Y 1 S GLY 121 F E GLY 127 
142 1 Y 1 S GLY 121 G E GLY 128 
143 1 Y 1 S GLY 121 H E GLY 129 
144 1 Y 1 S GLY 121 I E GLY 130 
145 1 Y 1 S SER 121 J E SER 131 
146 1 Y 1 S GLY 121 K E GLY 132 
147 1 Y 1 S GLY 121 L E GLY 133 
148 1 Y 1 S GLY 121 M E GLY 134 
149 1 Y 1 S GLY 121 N E GLY 135 
150 1 Y 1 S SER 121 O E SER 136 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
XOT C1   C N R 388 
XOT C2   C N N 389 
XOT C3   C Y N 390 
XOT C4   C Y N 391 
XOT C5   C Y N 392 
XOT C6   C N N 393 
XOT C7   C N R 394 
XOT C8   C N N 395 
XOT N1   N Y N 396 
XOT N2   N Y N 397 
XOT O1   O N N 398 
XOT O2   O N N 399 
XOT H1   H N N 400 
XOT H2   H N N 401 
XOT H3   H N N 402 
XOT H4   H N N 403 
XOT H5   H N N 404 
XOT H6   H N N 405 
XOT H7   H N N 406 
XOT H8   H N N 407 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
XOT C7  C8   sing N N 374 
XOT C7  C1   sing N N 375 
XOT C7  C4   sing N N 376 
XOT C8  C1   sing N N 377 
XOT C1  C2   sing N N 378 
XOT C4  N1   sing Y N 379 
XOT C4  C3   doub Y N 380 
XOT N1  N2   sing Y N 381 
XOT C2  C3   sing N N 382 
XOT C3  C5   sing Y N 383 
XOT N2  C5   doub Y N 384 
XOT C5  C6   sing N N 385 
XOT C6  O1   doub N N 386 
XOT C6  O2   sing N N 387 
XOT C1  H1   sing N N 388 
XOT C2  H2   sing N N 389 
XOT C2  H3   sing N N 390 
XOT C7  H4   sing N N 391 
XOT C8  H5   sing N N 392 
XOT C8  H6   sing N N 393 
XOT N1  H7   sing N N 394 
XOT O2  H8   sing N N 395 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-08-01 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9IZC 
_em_admin.last_update        2025-04-02 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'Cryo-EM structure of human HCAR2-Gi complex with MK1903' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         56 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9IZC 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP A 1 1   ? 119.559 147.590 76.475  1.00 173.37 ?  8   ASP A N   1 
ATOM   2    C CA  . ASP A 1 1   ? 119.290 146.170 76.670  1.00 174.74 ?  8   ASP A CA  1 
ATOM   3    C C   . ASP A 1 1   ? 119.296 145.805 78.149  1.00 174.83 ?  8   ASP A C   1 
ATOM   4    O O   . ASP A 1 1   ? 118.242 145.614 78.754  1.00 173.48 ?  8   ASP A O   1 
ATOM   5    C CB  . ASP A 1 1   ? 120.317 145.320 75.919  1.00 175.11 ?  8   ASP A CB  1 
ATOM   6    C CG  . ASP A 1 1   ? 120.543 145.799 74.500  1.00 174.80 ?  8   ASP A CG  1 
ATOM   7    O OD1 . ASP A 1 1   ? 119.548 145.982 73.769  1.00 175.24 ?  8   ASP A OD1 1 
ATOM   8    O OD2 . ASP A 1 1   ? 121.715 145.991 74.116  1.00 172.87 -1 8   ASP A OD2 1 
ATOM   9    N N   . HIS A 1 2   ? 120.493 145.705 78.729  1.00 175.97 ?  9   HIS A N   1 
ATOM   10   C CA  . HIS A 1 2   ? 120.635 145.349 80.131  1.00 174.37 ?  9   HIS A CA  1 
ATOM   11   C C   . HIS A 1 2   ? 121.510 146.320 80.912  1.00 174.31 ?  9   HIS A C   1 
ATOM   12   O O   . HIS A 1 2   ? 121.574 146.217 82.141  1.00 174.23 ?  9   HIS A O   1 
ATOM   13   C CB  . HIS A 1 2   ? 121.206 143.931 80.266  1.00 173.11 ?  9   HIS A CB  1 
ATOM   14   C CG  . HIS A 1 2   ? 120.240 142.856 79.878  1.00 175.51 ?  9   HIS A CG  1 
ATOM   15   N ND1 . HIS A 1 2   ? 119.210 142.450 80.699  1.00 176.32 ?  9   HIS A ND1 1 
ATOM   16   C CD2 . HIS A 1 2   ? 120.167 142.078 78.772  1.00 173.76 ?  9   HIS A CD2 1 
ATOM   17   C CE1 . HIS A 1 2   ? 118.530 141.485 80.105  1.00 174.69 ?  9   HIS A CE1 1 
ATOM   18   N NE2 . HIS A 1 2   ? 119.090 141.241 78.935  1.00 173.83 ?  9   HIS A NE2 1 
ATOM   19   N N   . PHE A 1 3   ? 122.183 147.250 80.239  1.00 181.88 ?  10  PHE A N   1 
ATOM   20   C CA  . PHE A 1 3   ? 122.986 148.253 80.922  1.00 182.10 ?  10  PHE A CA  1 
ATOM   21   C C   . PHE A 1 3   ? 122.095 149.135 81.791  1.00 183.34 ?  10  PHE A C   1 
ATOM   22   O O   . PHE A 1 3   ? 120.976 149.491 81.413  1.00 183.38 ?  10  PHE A O   1 
ATOM   23   C CB  . PHE A 1 3   ? 123.766 149.077 79.882  1.00 180.80 ?  10  PHE A CB  1 
ATOM   24   C CG  . PHE A 1 3   ? 124.471 150.301 80.430  1.00 181.89 ?  10  PHE A CG  1 
ATOM   25   C CD1 . PHE A 1 3   ? 123.764 151.434 80.813  1.00 182.39 ?  10  PHE A CD1 1 
ATOM   26   C CD2 . PHE A 1 3   ? 125.854 150.353 80.451  1.00 184.12 ?  10  PHE A CD2 1 
ATOM   27   C CE1 . PHE A 1 3   ? 124.418 152.553 81.287  1.00 182.98 ?  10  PHE A CE1 1 
ATOM   28   C CE2 . PHE A 1 3   ? 126.518 151.473 80.924  1.00 184.69 ?  10  PHE A CE2 1 
ATOM   29   C CZ  . PHE A 1 3   ? 125.799 152.575 81.338  1.00 184.52 ?  10  PHE A CZ  1 
ATOM   30   N N   . LEU A 1 4   ? 122.603 149.479 82.973  1.00 187.62 ?  11  LEU A N   1 
ATOM   31   C CA  . LEU A 1 4   ? 121.927 150.423 83.851  1.00 188.11 ?  11  LEU A CA  1 
ATOM   32   C C   . LEU A 1 4   ? 122.990 151.028 84.758  1.00 188.34 ?  11  LEU A C   1 
ATOM   33   O O   . LEU A 1 4   ? 124.046 150.427 84.958  1.00 189.83 ?  11  LEU A O   1 
ATOM   34   C CB  . LEU A 1 4   ? 120.801 149.730 84.638  1.00 188.24 ?  11  LEU A CB  1 
ATOM   35   C CG  . LEU A 1 4   ? 119.899 150.392 85.694  1.00 189.13 ?  11  LEU A CG  1 
ATOM   36   C CD1 . LEU A 1 4   ? 120.589 150.816 86.971  1.00 188.92 ?  11  LEU A CD1 1 
ATOM   37   C CD2 . LEU A 1 4   ? 119.168 151.577 85.073  1.00 187.06 ?  11  LEU A CD2 1 
ATOM   38   N N   . GLU A 1 5   ? 122.719 152.219 85.285  1.00 190.14 ?  12  GLU A N   1 
ATOM   39   C CA  . GLU A 1 5   ? 123.736 153.010 85.970  1.00 190.59 ?  12  GLU A CA  1 
ATOM   40   C C   . GLU A 1 5   ? 123.561 152.866 87.483  1.00 190.03 ?  12  GLU A C   1 
ATOM   41   O O   . GLU A 1 5   ? 122.708 153.534 88.075  1.00 189.80 ?  12  GLU A O   1 
ATOM   42   C CB  . GLU A 1 5   ? 123.618 154.476 85.559  1.00 189.28 ?  12  GLU A CB  1 
ATOM   43   C CG  . GLU A 1 5   ? 124.935 155.230 85.457  1.00 189.40 ?  12  GLU A CG  1 
ATOM   44   C CD  . GLU A 1 5   ? 125.805 154.727 84.310  1.00 190.39 ?  12  GLU A CD  1 
ATOM   45   O OE1 . GLU A 1 5   ? 125.972 155.485 83.331  1.00 188.79 ?  12  GLU A OE1 1 
ATOM   46   O OE2 . GLU A 1 5   ? 126.290 153.577 84.355  1.00 190.70 -1 12  GLU A OE2 1 
ATOM   47   N N   . ILE A 1 6   ? 124.367 152.007 88.115  1.00 188.91 ?  13  ILE A N   1 
ATOM   48   C CA  . ILE A 1 6   ? 124.381 151.940 89.577  1.00 189.63 ?  13  ILE A CA  1 
ATOM   49   C C   . ILE A 1 6   ? 125.430 152.911 90.101  1.00 189.46 ?  13  ILE A C   1 
ATOM   50   O O   . ILE A 1 6   ? 126.542 152.502 90.452  1.00 188.96 ?  13  ILE A O   1 
ATOM   51   C CB  . ILE A 1 6   ? 124.678 150.517 90.094  1.00 189.75 ?  13  ILE A CB  1 
ATOM   52   C CG1 . ILE A 1 6   ? 123.713 149.492 89.509  1.00 188.75 ?  13  ILE A CG1 1 
ATOM   53   C CG2 . ILE A 1 6   ? 124.583 150.468 91.615  1.00 188.49 ?  13  ILE A CG2 1 
ATOM   54   C CD1 . ILE A 1 6   ? 122.286 149.815 89.767  1.00 188.14 ?  13  ILE A CD1 1 
ATOM   55   N N   . ASP A 1 7   ? 125.081 154.199 90.161  1.00 189.87 ?  14  ASP A N   1 
ATOM   56   C CA  . ASP A 1 7   ? 125.939 155.245 90.733  1.00 189.47 ?  14  ASP A CA  1 
ATOM   57   C C   . ASP A 1 7   ? 127.393 155.113 90.274  1.00 189.62 ?  14  ASP A C   1 
ATOM   58   O O   . ASP A 1 7   ? 128.324 155.545 90.956  1.00 188.76 ?  14  ASP A O   1 
ATOM   59   C CB  . ASP A 1 7   ? 125.849 155.242 92.259  1.00 189.03 ?  14  ASP A CB  1 
ATOM   60   C CG  . ASP A 1 7   ? 124.435 155.011 92.758  1.00 188.31 ?  14  ASP A CG  1 
ATOM   61   O OD1 . ASP A 1 7   ? 123.910 153.895 92.566  1.00 188.14 ?  14  ASP A OD1 1 
ATOM   62   O OD2 . ASP A 1 7   ? 123.849 155.946 93.343  1.00 187.35 -1 14  ASP A OD2 1 
ATOM   63   N N   . LYS A 1 8   ? 127.582 154.525 89.092  1.00 189.68 ?  15  LYS A N   1 
ATOM   64   C CA  . LYS A 1 8   ? 128.894 154.155 88.573  1.00 188.54 ?  15  LYS A CA  1 
ATOM   65   C C   . LYS A 1 8   ? 128.721 153.719 87.124  1.00 188.40 ?  15  LYS A C   1 
ATOM   66   O O   . LYS A 1 8   ? 127.618 153.826 86.583  1.00 189.10 ?  15  LYS A O   1 
ATOM   67   C CB  . LYS A 1 8   ? 129.530 153.045 89.420  1.00 187.85 ?  15  LYS A CB  1 
ATOM   68   C CG  . LYS A 1 8   ? 131.055 152.954 89.332  1.00 187.81 ?  15  LYS A CG  1 
ATOM   69   C CD  . LYS A 1 8   ? 131.740 154.301 89.553  1.00 188.97 ?  15  LYS A CD  1 
ATOM   70   C CE  . LYS A 1 8   ? 131.382 154.916 90.900  1.00 188.39 ?  15  LYS A CE  1 
ATOM   71   N NZ  . LYS A 1 8   ? 131.843 156.328 91.005  1.00 186.88 1  15  LYS A NZ  1 
ATOM   72   N N   . LYS A 1 9   ? 129.778 153.218 86.491  1.00 186.31 ?  16  LYS A N   1 
ATOM   73   C CA  . LYS A 1 9   ? 129.780 152.947 85.059  1.00 187.99 ?  16  LYS A CA  1 
ATOM   74   C C   . LYS A 1 9   ? 129.689 151.454 84.772  1.00 187.63 ?  16  LYS A C   1 
ATOM   75   O O   . LYS A 1 9   ? 130.334 150.642 85.442  1.00 185.85 ?  16  LYS A O   1 
ATOM   76   C CB  . LYS A 1 9   ? 131.043 153.515 84.403  1.00 186.49 ?  16  LYS A CB  1 
ATOM   77   C CG  . LYS A 1 9   ? 130.954 153.665 82.893  1.00 186.19 ?  16  LYS A CG  1 
ATOM   78   C CD  . LYS A 1 9   ? 129.837 154.611 82.492  1.00 186.07 ?  16  LYS A CD  1 
ATOM   79   C CE  . LYS A 1 9   ? 130.184 155.348 81.209  1.00 184.68 ?  16  LYS A CE  1 
ATOM   80   N NZ  . LYS A 1 9   ? 130.213 154.433 80.035  1.00 184.62 1  16  LYS A NZ  1 
ATOM   81   N N   . ASN A 1 10  ? 128.876 151.109 83.767  1.00 187.29 ?  17  ASN A N   1 
ATOM   82   C CA  . ASN A 1 10  ? 128.878 149.788 83.127  1.00 187.06 ?  17  ASN A CA  1 
ATOM   83   C C   . ASN A 1 10  ? 128.325 148.685 84.031  1.00 185.94 ?  17  ASN A C   1 
ATOM   84   O O   . ASN A 1 10  ? 128.897 147.598 84.121  1.00 184.98 ?  17  ASN A O   1 
ATOM   85   C CB  . ASN A 1 10  ? 130.277 149.418 82.628  1.00 186.87 ?  17  ASN A CB  1 
ATOM   86   C CG  . ASN A 1 10  ? 130.511 149.836 81.190  1.00 185.19 ?  17  ASN A CG  1 
ATOM   87   O OD1 . ASN A 1 10  ? 129.744 150.615 80.625  1.00 183.32 ?  17  ASN A OD1 1 
ATOM   88   N ND2 . ASN A 1 10  ? 131.575 149.317 80.590  1.00 184.73 ?  17  ASN A ND2 1 
ATOM   89   N N   . CYS A 1 11  ? 127.202 148.950 84.694  1.00 186.63 ?  18  CYS A N   1 
ATOM   90   C CA  . CYS A 1 11  ? 126.505 147.931 85.475  1.00 186.04 ?  18  CYS A CA  1 
ATOM   91   C C   . CYS A 1 11  ? 125.503 147.221 84.573  1.00 185.24 ?  18  CYS A C   1 
ATOM   92   O O   . CYS A 1 11  ? 124.632 147.861 83.976  1.00 186.94 ?  18  CYS A O   1 
ATOM   93   C CB  . CYS A 1 11  ? 125.816 148.551 86.685  1.00 187.43 ?  18  CYS A CB  1 
ATOM   94   S SG  . CYS A 1 11  ? 126.839 149.713 87.603  1.00 190.25 ?  18  CYS A SG  1 
ATOM   95   N N   . CYS A 1 12  ? 125.628 145.901 84.470  1.00 174.80 ?  19  CYS A N   1 
ATOM   96   C CA  . CYS A 1 12  ? 124.751 145.097 83.622  1.00 176.02 ?  19  CYS A CA  1 
ATOM   97   C C   . CYS A 1 12  ? 123.960 144.151 84.516  1.00 176.77 ?  19  CYS A C   1 
ATOM   98   O O   . CYS A 1 12  ? 124.348 143.005 84.740  1.00 176.40 ?  19  CYS A O   1 
ATOM   99   C CB  . CYS A 1 12  ? 125.557 144.345 82.572  1.00 176.53 ?  19  CYS A CB  1 
ATOM   100  S SG  . CYS A 1 12  ? 126.264 145.416 81.304  1.00 184.85 ?  19  CYS A SG  1 
ATOM   101  N N   . VAL A 1 13  ? 122.832 144.640 85.020  1.00 176.88 ?  20  VAL A N   1 
ATOM   102  C CA  . VAL A 1 13  ? 121.926 143.854 85.847  1.00 174.94 ?  20  VAL A CA  1 
ATOM   103  C C   . VAL A 1 13  ? 120.777 143.378 84.974  1.00 173.22 ?  20  VAL A C   1 
ATOM   104  O O   . VAL A 1 13  ? 120.436 144.001 83.961  1.00 173.67 ?  20  VAL A O   1 
ATOM   105  C CB  . VAL A 1 13  ? 121.428 144.664 87.065  1.00 173.44 ?  20  VAL A CB  1 
ATOM   106  C CG1 . VAL A 1 13  ? 122.272 145.916 87.247  1.00 174.28 ?  20  VAL A CG1 1 
ATOM   107  C CG2 . VAL A 1 13  ? 119.956 145.032 86.920  1.00 172.89 ?  20  VAL A CG2 1 
ATOM   108  N N   . PHE A 1 14  ? 120.180 142.252 85.356  1.00 172.49 ?  21  PHE A N   1 
ATOM   109  C CA  . PHE A 1 14  ? 119.190 141.608 84.510  1.00 173.24 ?  21  PHE A CA  1 
ATOM   110  C C   . PHE A 1 14  ? 118.314 140.693 85.352  1.00 174.29 ?  21  PHE A C   1 
ATOM   111  O O   . PHE A 1 14  ? 118.748 140.134 86.361  1.00 173.02 ?  21  PHE A O   1 
ATOM   112  C CB  . PHE A 1 14  ? 119.889 140.878 83.349  1.00 173.76 ?  21  PHE A CB  1 
ATOM   113  C CG  . PHE A 1 14  ? 120.132 139.413 83.580  1.00 175.45 ?  21  PHE A CG  1 
ATOM   114  C CD1 . PHE A 1 14  ? 119.130 138.472 83.410  1.00 175.52 ?  21  PHE A CD1 1 
ATOM   115  C CD2 . PHE A 1 14  ? 121.388 138.978 83.958  1.00 175.15 ?  21  PHE A CD2 1 
ATOM   116  C CE1 . PHE A 1 14  ? 119.384 137.133 83.624  1.00 175.18 ?  21  PHE A CE1 1 
ATOM   117  C CE2 . PHE A 1 14  ? 121.638 137.642 84.171  1.00 176.02 ?  21  PHE A CE2 1 
ATOM   118  C CZ  . PHE A 1 14  ? 120.636 136.718 84.003  1.00 175.78 ?  21  PHE A CZ  1 
ATOM   119  N N   . ARG A 1 15  ? 117.065 140.547 84.909  1.00 178.95 ?  22  ARG A N   1 
ATOM   120  C CA  . ARG A 1 15  ? 116.035 139.779 85.608  1.00 178.38 ?  22  ARG A CA  1 
ATOM   121  C C   . ARG A 1 15  ? 115.430 138.784 84.622  1.00 179.01 ?  22  ARG A C   1 
ATOM   122  O O   . ARG A 1 15  ? 114.612 139.160 83.777  1.00 177.50 ?  22  ARG A O   1 
ATOM   123  C CB  . ARG A 1 15  ? 114.957 140.697 86.178  1.00 178.35 ?  22  ARG A CB  1 
ATOM   124  C CG  . ARG A 1 15  ? 115.446 142.064 86.628  1.00 177.58 ?  22  ARG A CG  1 
ATOM   125  C CD  . ARG A 1 15  ? 114.284 142.964 87.025  1.00 178.22 ?  22  ARG A CD  1 
ATOM   126  N NE  . ARG A 1 15  ? 113.134 142.791 86.145  1.00 179.25 ?  22  ARG A NE  1 
ATOM   127  C CZ  . ARG A 1 15  ? 111.968 142.283 86.520  1.00 178.33 ?  22  ARG A CZ  1 
ATOM   128  N NH1 . ARG A 1 15  ? 111.756 141.879 87.762  1.00 176.69 1  22  ARG A NH1 1 
ATOM   129  N NH2 . ARG A 1 15  ? 110.991 142.175 85.625  1.00 177.06 ?  22  ARG A NH2 1 
ATOM   130  N N   . ASP A 1 16  ? 115.825 137.521 84.729  1.00 183.56 ?  23  ASP A N   1 
ATOM   131  C CA  . ASP A 1 16  ? 115.296 136.456 83.889  1.00 184.39 ?  23  ASP A CA  1 
ATOM   132  C C   . ASP A 1 16  ? 114.685 135.365 84.763  1.00 184.72 ?  23  ASP A C   1 
ATOM   133  O O   . ASP A 1 16  ? 114.700 135.436 85.995  1.00 183.62 ?  23  ASP A O   1 
ATOM   134  C CB  . ASP A 1 16  ? 116.393 135.891 82.984  1.00 181.86 ?  23  ASP A CB  1 
ATOM   135  C CG  . ASP A 1 16  ? 115.842 135.200 81.755  1.00 181.84 ?  23  ASP A CG  1 
ATOM   136  O OD1 . ASP A 1 16  ? 115.256 135.892 80.896  1.00 181.20 ?  23  ASP A OD1 1 
ATOM   137  O OD2 . ASP A 1 16  ? 115.999 133.966 81.648  1.00 181.67 -1 23  ASP A OD2 1 
ATOM   138  N N   . ASP A 1 17  ? 114.149 134.340 84.109  1.00 187.98 ?  24  ASP A N   1 
ATOM   139  C CA  . ASP A 1 17  ? 113.583 133.200 84.816  1.00 185.87 ?  24  ASP A CA  1 
ATOM   140  C C   . ASP A 1 17  ? 114.721 132.295 85.286  1.00 186.96 ?  24  ASP A C   1 
ATOM   141  O O   . ASP A 1 17  ? 115.892 132.683 85.287  1.00 186.41 ?  24  ASP A O   1 
ATOM   142  C CB  . ASP A 1 17  ? 112.565 132.477 83.936  1.00 185.10 ?  24  ASP A CB  1 
ATOM   143  C CG  . ASP A 1 17  ? 113.214 131.587 82.899  1.00 186.70 ?  24  ASP A CG  1 
ATOM   144  O OD1 . ASP A 1 17  ? 113.767 132.122 81.917  1.00 187.19 ?  24  ASP A OD1 1 
ATOM   145  O OD2 . ASP A 1 17  ? 113.164 130.351 83.066  1.00 186.79 -1 24  ASP A OD2 1 
ATOM   146  N N   . PHE A 1 18  ? 114.376 131.083 85.723  1.00 185.18 ?  25  PHE A N   1 
ATOM   147  C CA  . PHE A 1 18  ? 115.274 130.175 86.440  1.00 184.20 ?  25  PHE A CA  1 
ATOM   148  C C   . PHE A 1 18  ? 115.744 130.762 87.767  1.00 183.58 ?  25  PHE A C   1 
ATOM   149  O O   . PHE A 1 18  ? 116.526 130.130 88.484  1.00 183.40 ?  25  PHE A O   1 
ATOM   150  C CB  . PHE A 1 18  ? 116.494 129.755 85.602  1.00 184.24 ?  25  PHE A CB  1 
ATOM   151  C CG  . PHE A 1 18  ? 116.210 129.578 84.136  1.00 184.79 ?  25  PHE A CG  1 
ATOM   152  C CD1 . PHE A 1 18  ? 115.609 128.421 83.671  1.00 182.78 ?  25  PHE A CD1 1 
ATOM   153  C CD2 . PHE A 1 18  ? 116.590 130.544 83.218  1.00 184.58 ?  25  PHE A CD2 1 
ATOM   154  C CE1 . PHE A 1 18  ? 115.360 128.246 82.323  1.00 182.84 ?  25  PHE A CE1 1 
ATOM   155  C CE2 . PHE A 1 18  ? 116.345 130.375 81.870  1.00 184.78 ?  25  PHE A CE2 1 
ATOM   156  C CZ  . PHE A 1 18  ? 115.729 129.224 81.422  1.00 184.09 ?  25  PHE A CZ  1 
ATOM   157  N N   . ILE A 1 19  ? 115.280 131.960 88.116  1.00 178.61 ?  26  ILE A N   1 
ATOM   158  C CA  . ILE A 1 19  ? 115.582 132.545 89.415  1.00 178.35 ?  26  ILE A CA  1 
ATOM   159  C C   . ILE A 1 19  ? 114.413 132.229 90.330  1.00 179.15 ?  26  ILE A C   1 
ATOM   160  O O   . ILE A 1 19  ? 114.560 131.491 91.314  1.00 178.21 ?  26  ILE A O   1 
ATOM   161  C CB  . ILE A 1 19  ? 115.830 134.061 89.323  1.00 178.85 ?  26  ILE A CB  1 
ATOM   162  C CG1 . ILE A 1 19  ? 116.899 134.366 88.274  1.00 177.96 ?  26  ILE A CG1 1 
ATOM   163  C CG2 . ILE A 1 19  ? 116.238 134.615 90.678  1.00 177.11 ?  26  ILE A CG2 1 
ATOM   164  C CD1 . ILE A 1 19  ? 117.282 135.826 88.198  1.00 176.43 ?  26  ILE A CD1 1 
ATOM   165  N N   . VAL A 1 20  ? 113.232 132.762 90.009  1.00 184.25 ?  27  VAL A N   1 
ATOM   166  C CA  . VAL A 1 20  ? 112.052 132.279 90.709  1.00 184.63 ?  27  VAL A CA  1 
ATOM   167  C C   . VAL A 1 20  ? 111.542 131.096 89.897  1.00 182.95 ?  27  VAL A C   1 
ATOM   168  O O   . VAL A 1 20  ? 110.492 131.145 89.245  1.00 181.10 ?  27  VAL A O   1 
ATOM   169  C CB  . VAL A 1 20  ? 111.003 133.398 90.891  1.00 183.74 ?  27  VAL A CB  1 
ATOM   170  C CG1 . VAL A 1 20  ? 110.710 134.119 89.571  1.00 181.73 ?  27  VAL A CG1 1 
ATOM   171  C CG2 . VAL A 1 20  ? 109.728 132.876 91.567  1.00 182.37 ?  27  VAL A CG2 1 
ATOM   172  N N   . LYS A 1 21  ? 112.324 130.031 89.921  1.00 179.49 ?  28  LYS A N   1 
ATOM   173  C CA  . LYS A 1 21  ? 111.907 128.654 89.703  1.00 179.41 ?  28  LYS A CA  1 
ATOM   174  C C   . LYS A 1 21  ? 112.645 127.682 90.608  1.00 179.98 ?  28  LYS A C   1 
ATOM   175  O O   . LYS A 1 21  ? 112.117 126.603 90.893  1.00 179.60 ?  28  LYS A O   1 
ATOM   176  C CB  . LYS A 1 21  ? 112.126 128.250 88.239  1.00 179.08 ?  28  LYS A CB  1 
ATOM   177  C CG  . LYS A 1 21  ? 111.365 127.010 87.807  1.00 177.76 ?  28  LYS A CG  1 
ATOM   178  C CD  . LYS A 1 21  ? 110.122 127.387 87.020  1.00 177.98 ?  28  LYS A CD  1 
ATOM   179  C CE  . LYS A 1 21  ? 110.449 127.609 85.553  1.00 177.65 ?  28  LYS A CE  1 
ATOM   180  N NZ  . LYS A 1 21  ? 109.454 128.493 84.884  1.00 177.07 1  28  LYS A NZ  1 
ATOM   181  N N   . VAL A 1 22  ? 113.841 128.039 91.078  1.00 181.64 ?  29  VAL A N   1 
ATOM   182  C CA  . VAL A 1 22  ? 114.690 127.168 91.878  1.00 181.16 ?  29  VAL A CA  1 
ATOM   183  C C   . VAL A 1 22  ? 115.122 127.894 93.146  1.00 179.49 ?  29  VAL A C   1 
ATOM   184  O O   . VAL A 1 22  ? 115.503 127.252 94.130  1.00 177.13 ?  29  VAL A O   1 
ATOM   185  C CB  . VAL A 1 22  ? 115.915 126.684 91.075  1.00 180.07 ?  29  VAL A CB  1 
ATOM   186  C CG1 . VAL A 1 22  ? 115.538 126.390 89.628  1.00 178.35 ?  29  VAL A CG1 1 
ATOM   187  C CG2 . VAL A 1 22  ? 117.041 127.704 91.135  1.00 178.87 ?  29  VAL A CG2 1 
ATOM   188  N N   . LEU A 1 23  ? 115.065 129.234 93.149  1.00 176.92 ?  30  LEU A N   1 
ATOM   189  C CA  . LEU A 1 23  ? 115.480 129.974 94.332  1.00 176.29 ?  30  LEU A CA  1 
ATOM   190  C C   . LEU A 1 23  ? 114.399 129.936 95.415  1.00 177.72 ?  30  LEU A C   1 
ATOM   191  O O   . LEU A 1 23  ? 114.741 129.815 96.599  1.00 178.09 ?  30  LEU A O   1 
ATOM   192  C CB  . LEU A 1 23  ? 115.826 131.420 93.960  1.00 175.28 ?  30  LEU A CB  1 
ATOM   193  C CG  . LEU A 1 23  ? 117.302 131.787 93.764  1.00 175.90 ?  30  LEU A CG  1 
ATOM   194  C CD1 . LEU A 1 23  ? 118.089 131.733 95.050  1.00 175.65 ?  30  LEU A CD1 1 
ATOM   195  C CD2 . LEU A 1 23  ? 117.936 130.888 92.725  1.00 176.22 ?  30  LEU A CD2 1 
ATOM   196  N N   . PRO A 1 24  ? 113.109 130.059 95.081  1.00 177.75 ?  31  PRO A N   1 
ATOM   197  C CA  . PRO A 1 24  ? 112.065 129.974 96.116  1.00 176.29 ?  31  PRO A CA  1 
ATOM   198  C C   . PRO A 1 24  ? 112.165 128.712 96.958  1.00 176.10 ?  31  PRO A C   1 
ATOM   199  O O   . PRO A 1 24  ? 112.169 128.808 98.195  1.00 174.05 ?  31  PRO A O   1 
ATOM   200  C CB  . PRO A 1 24  ? 110.749 130.022 95.316  1.00 176.23 ?  31  PRO A CB  1 
ATOM   201  C CG  . PRO A 1 24  ? 111.126 130.299 93.893  1.00 175.38 ?  31  PRO A CG  1 
ATOM   202  C CD  . PRO A 1 24  ? 112.565 130.675 93.858  1.00 175.38 ?  31  PRO A CD  1 
ATOM   203  N N   . PRO A 1 25  ? 112.238 127.514 96.360  1.00 180.62 ?  32  PRO A N   1 
ATOM   204  C CA  . PRO A 1 25  ? 112.285 126.320 97.220  1.00 181.42 ?  32  PRO A CA  1 
ATOM   205  C C   . PRO A 1 25  ? 113.584 126.201 97.993  1.00 181.87 ?  32  PRO A C   1 
ATOM   206  O O   . PRO A 1 25  ? 113.571 125.838 99.179  1.00 180.38 ?  32  PRO A O   1 
ATOM   207  C CB  . PRO A 1 25  ? 112.101 125.159 96.228  1.00 180.08 ?  32  PRO A CB  1 
ATOM   208  C CG  . PRO A 1 25  ? 111.662 125.791 94.944  1.00 179.74 ?  32  PRO A CG  1 
ATOM   209  C CD  . PRO A 1 25  ? 112.310 127.126 94.941  1.00 179.42 ?  32  PRO A CD  1 
ATOM   210  N N   . VAL A 1 26  ? 114.715 126.496 97.347  1.00 177.84 ?  33  VAL A N   1 
ATOM   211  C CA  . VAL A 1 26  ? 116.012 126.368 97.997  1.00 176.12 ?  33  VAL A CA  1 
ATOM   212  C C   . VAL A 1 26  ? 116.235 127.414 99.078  1.00 174.58 ?  33  VAL A C   1 
ATOM   213  O O   . VAL A 1 26  ? 117.124 127.237 99.912  1.00 175.49 ?  33  VAL A O   1 
ATOM   214  C CB  . VAL A 1 26  ? 117.140 126.408 96.944  1.00 175.68 ?  33  VAL A CB  1 
ATOM   215  C CG1 . VAL A 1 26  ? 117.521 127.832 96.611  1.00 174.37 ?  33  VAL A CG1 1 
ATOM   216  C CG2 . VAL A 1 26  ? 118.353 125.625 97.430  1.00 174.39 ?  33  VAL A CG2 1 
ATOM   217  N N   . LEU A 1 27  ? 115.455 128.495 99.094  1.00 171.16 ?  34  LEU A N   1 
ATOM   218  C CA  . LEU A 1 27  ? 115.461 129.408 100.233 1.00 171.95 ?  34  LEU A CA  1 
ATOM   219  C C   . LEU A 1 27  ? 114.412 129.070 101.280 1.00 171.58 ?  34  LEU A C   1 
ATOM   220  O O   . LEU A 1 27  ? 114.666 129.258 102.468 1.00 171.49 ?  34  LEU A O   1 
ATOM   221  C CB  . LEU A 1 27  ? 115.276 130.865 99.790  1.00 173.34 ?  34  LEU A CB  1 
ATOM   222  C CG  . LEU A 1 27  ? 116.435 131.685 99.209  1.00 173.17 ?  34  LEU A CG  1 
ATOM   223  C CD1 . LEU A 1 27  ? 117.291 132.217 100.344 1.00 171.90 ?  34  LEU A CD1 1 
ATOM   224  C CD2 . LEU A 1 27  ? 117.297 130.882 98.282  1.00 171.75 ?  34  LEU A CD2 1 
ATOM   225  N N   . GLY A 1 28  ? 113.240 128.572 100.881 1.00 169.58 ?  35  GLY A N   1 
ATOM   226  C CA  . GLY A 1 28  ? 112.248 128.187 101.871 1.00 169.42 ?  35  GLY A CA  1 
ATOM   227  C C   . GLY A 1 28  ? 112.705 127.025 102.732 1.00 171.24 ?  35  GLY A C   1 
ATOM   228  O O   . GLY A 1 28  ? 112.515 127.031 103.955 1.00 172.00 ?  35  GLY A O   1 
ATOM   229  N N   . LEU A 1 29  ? 113.311 126.010 102.109 1.00 171.47 ?  36  LEU A N   1 
ATOM   230  C CA  . LEU A 1 29  ? 113.818 124.876 102.874 1.00 172.85 ?  36  LEU A CA  1 
ATOM   231  C C   . LEU A 1 29  ? 114.904 125.316 103.848 1.00 173.11 ?  36  LEU A C   1 
ATOM   232  O O   . LEU A 1 29  ? 114.902 124.912 105.018 1.00 170.52 ?  36  LEU A O   1 
ATOM   233  C CB  . LEU A 1 29  ? 114.342 123.798 101.924 1.00 171.58 ?  36  LEU A CB  1 
ATOM   234  C CG  . LEU A 1 29  ? 114.786 122.460 102.521 1.00 171.69 ?  36  LEU A CG  1 
ATOM   235  C CD1 . LEU A 1 29  ? 114.375 121.314 101.611 1.00 170.06 ?  36  LEU A CD1 1 
ATOM   236  C CD2 . LEU A 1 29  ? 116.290 122.436 102.755 1.00 170.97 ?  36  LEU A CD2 1 
ATOM   237  N N   . GLU A 1 30  ? 115.837 126.152 103.382 1.00 168.93 ?  37  GLU A N   1 
ATOM   238  C CA  . GLU A 1 30  ? 116.870 126.674 104.269 1.00 167.27 ?  37  GLU A CA  1 
ATOM   239  C C   . GLU A 1 30  ? 116.257 127.477 105.404 1.00 166.97 ?  37  GLU A C   1 
ATOM   240  O O   . GLU A 1 30  ? 116.654 127.326 106.563 1.00 166.58 ?  37  GLU A O   1 
ATOM   241  C CB  . GLU A 1 30  ? 117.858 127.542 103.491 1.00 165.78 ?  37  GLU A CB  1 
ATOM   242  C CG  . GLU A 1 30  ? 118.717 126.790 102.500 1.00 166.86 ?  37  GLU A CG  1 
ATOM   243  C CD  . GLU A 1 30  ? 119.530 127.721 101.627 1.00 168.14 ?  37  GLU A CD  1 
ATOM   244  O OE1 . GLU A 1 30  ? 119.508 128.943 101.878 1.00 165.81 ?  37  GLU A OE1 1 
ATOM   245  O OE2 . GLU A 1 30  ? 120.176 127.234 100.677 1.00 167.86 -1 37  GLU A OE2 1 
ATOM   246  N N   . PHE A 1 31  ? 115.277 128.327 105.091 1.00 169.44 ?  38  PHE A N   1 
ATOM   247  C CA  . PHE A 1 31  ? 114.639 129.138 106.118 1.00 168.61 ?  38  PHE A CA  1 
ATOM   248  C C   . PHE A 1 31  ? 114.044 128.260 107.205 1.00 169.33 ?  38  PHE A C   1 
ATOM   249  O O   . PHE A 1 31  ? 114.349 128.433 108.389 1.00 169.21 ?  38  PHE A O   1 
ATOM   250  C CB  . PHE A 1 31  ? 113.562 130.022 105.491 1.00 167.22 ?  38  PHE A CB  1 
ATOM   251  C CG  . PHE A 1 31  ? 113.047 131.090 106.410 1.00 168.80 ?  38  PHE A CG  1 
ATOM   252  C CD1 . PHE A 1 31  ? 113.853 131.609 107.408 1.00 169.28 ?  38  PHE A CD1 1 
ATOM   253  C CD2 . PHE A 1 31  ? 111.755 131.568 106.282 1.00 168.68 ?  38  PHE A CD2 1 
ATOM   254  C CE1 . PHE A 1 31  ? 113.383 132.591 108.255 1.00 168.78 ?  38  PHE A CE1 1 
ATOM   255  C CE2 . PHE A 1 31  ? 111.278 132.549 107.130 1.00 168.63 ?  38  PHE A CE2 1 
ATOM   256  C CZ  . PHE A 1 31  ? 112.094 133.060 108.118 1.00 168.56 ?  38  PHE A CZ  1 
ATOM   257  N N   . ILE A 1 32  ? 113.228 127.279 106.817 1.00 176.36 ?  39  ILE A N   1 
ATOM   258  C CA  . ILE A 1 32  ? 112.561 126.441 107.812 1.00 177.50 ?  39  ILE A CA  1 
ATOM   259  C C   . ILE A 1 32  ? 113.586 125.654 108.623 1.00 177.04 ?  39  ILE A C   1 
ATOM   260  O O   . ILE A 1 32  ? 113.575 125.675 109.864 1.00 176.27 ?  39  ILE A O   1 
ATOM   261  C CB  . ILE A 1 32  ? 111.542 125.508 107.133 1.00 177.10 ?  39  ILE A CB  1 
ATOM   262  C CG1 . ILE A 1 32  ? 110.442 126.326 106.454 1.00 174.36 ?  39  ILE A CG1 1 
ATOM   263  C CG2 . ILE A 1 32  ? 110.945 124.545 108.147 1.00 175.99 ?  39  ILE A CG2 1 
ATOM   264  C CD1 . ILE A 1 32  ? 109.391 125.484 105.770 1.00 173.08 ?  39  ILE A CD1 1 
ATOM   265  N N   . PHE A 1 33  ? 114.502 124.965 107.934 1.00 175.65 ?  40  PHE A N   1 
ATOM   266  C CA  . PHE A 1 33  ? 115.438 124.084 108.623 1.00 175.42 ?  40  PHE A CA  1 
ATOM   267  C C   . PHE A 1 33  ? 116.343 124.869 109.562 1.00 175.73 ?  40  PHE A C   1 
ATOM   268  O O   . PHE A 1 33  ? 116.480 124.529 110.744 1.00 173.84 ?  40  PHE A O   1 
ATOM   269  C CB  . PHE A 1 33  ? 116.272 123.305 107.603 1.00 174.98 ?  40  PHE A CB  1 
ATOM   270  C CG  . PHE A 1 33  ? 115.553 122.133 106.990 1.00 176.28 ?  40  PHE A CG  1 
ATOM   271  C CD1 . PHE A 1 33  ? 114.171 122.109 106.904 1.00 175.24 ?  40  PHE A CD1 1 
ATOM   272  C CD2 . PHE A 1 33  ? 116.267 121.055 106.494 1.00 175.15 ?  40  PHE A CD2 1 
ATOM   273  C CE1 . PHE A 1 33  ? 113.516 121.033 106.339 1.00 175.70 ?  40  PHE A CE1 1 
ATOM   274  C CE2 . PHE A 1 33  ? 115.617 119.976 105.927 1.00 174.98 ?  40  PHE A CE2 1 
ATOM   275  C CZ  . PHE A 1 33  ? 114.241 119.965 105.850 1.00 175.40 ?  40  PHE A CZ  1 
ATOM   276  N N   . GLY A 1 34  ? 116.974 125.928 109.050 1.00 174.26 ?  41  GLY A N   1 
ATOM   277  C CA  . GLY A 1 34  ? 117.862 126.721 109.872 1.00 172.87 ?  41  GLY A CA  1 
ATOM   278  C C   . GLY A 1 34  ? 117.151 127.471 110.977 1.00 172.78 ?  41  GLY A C   1 
ATOM   279  O O   . GLY A 1 34  ? 117.721 127.666 112.048 1.00 174.03 ?  41  GLY A O   1 
ATOM   280  N N   . LEU A 1 35  ? 115.911 127.909 110.742 1.00 170.14 ?  42  LEU A N   1 
ATOM   281  C CA  . LEU A 1 35  ? 115.155 128.548 111.810 1.00 170.47 ?  42  LEU A CA  1 
ATOM   282  C C   . LEU A 1 35  ? 114.922 127.577 112.954 1.00 171.51 ?  42  LEU A C   1 
ATOM   283  O O   . LEU A 1 35  ? 115.147 127.913 114.122 1.00 170.54 ?  42  LEU A O   1 
ATOM   284  C CB  . LEU A 1 35  ? 113.826 129.077 111.273 1.00 169.28 ?  42  LEU A CB  1 
ATOM   285  C CG  . LEU A 1 35  ? 113.667 130.596 111.225 1.00 169.84 ?  42  LEU A CG  1 
ATOM   286  C CD1 . LEU A 1 35  ? 112.194 130.971 111.185 1.00 169.63 ?  42  LEU A CD1 1 
ATOM   287  C CD2 . LEU A 1 35  ? 114.359 131.250 112.412 1.00 168.77 ?  42  LEU A CD2 1 
ATOM   288  N N   . LEU A 1 36  ? 114.497 126.352 112.634 1.00 176.20 ?  43  LEU A N   1 
ATOM   289  C CA  . LEU A 1 36  ? 114.306 125.351 113.679 1.00 177.05 ?  43  LEU A CA  1 
ATOM   290  C C   . LEU A 1 36  ? 115.617 125.062 114.405 1.00 176.69 ?  43  LEU A C   1 
ATOM   291  O O   . LEU A 1 36  ? 115.666 125.042 115.643 1.00 175.73 ?  43  LEU A O   1 
ATOM   292  C CB  . LEU A 1 36  ? 113.726 124.071 113.078 1.00 176.67 ?  43  LEU A CB  1 
ATOM   293  C CG  . LEU A 1 36  ? 112.210 123.896 113.185 1.00 176.24 ?  43  LEU A CG  1 
ATOM   294  C CD1 . LEU A 1 36  ? 111.493 124.774 112.175 1.00 175.04 ?  43  LEU A CD1 1 
ATOM   295  C CD2 . LEU A 1 36  ? 111.828 122.437 112.995 1.00 174.29 ?  43  LEU A CD2 1 
ATOM   296  N N   . GLY A 1 37  ? 116.696 124.860 113.646 1.00 170.59 ?  44  GLY A N   1 
ATOM   297  C CA  . GLY A 1 37  ? 117.970 124.524 114.264 1.00 170.10 ?  44  GLY A CA  1 
ATOM   298  C C   . GLY A 1 37  ? 118.504 125.635 115.147 1.00 170.87 ?  44  GLY A C   1 
ATOM   299  O O   . GLY A 1 37  ? 118.961 125.392 116.267 1.00 170.45 ?  44  GLY A O   1 
ATOM   300  N N   . ASN A 1 38  ? 118.455 126.874 114.653 1.00 168.63 ?  45  ASN A N   1 
ATOM   301  C CA  . ASN A 1 38  ? 118.956 128.008 115.417 1.00 169.53 ?  45  ASN A CA  1 
ATOM   302  C C   . ASN A 1 38  ? 118.092 128.278 116.639 1.00 169.26 ?  45  ASN A C   1 
ATOM   303  O O   . ASN A 1 38  ? 118.616 128.618 117.703 1.00 167.79 ?  45  ASN A O   1 
ATOM   304  C CB  . ASN A 1 38  ? 119.033 129.246 114.527 1.00 167.13 ?  45  ASN A CB  1 
ATOM   305  C CG  . ASN A 1 38  ? 120.084 129.116 113.447 1.00 167.59 ?  45  ASN A CG  1 
ATOM   306  O OD1 . ASN A 1 38  ? 121.195 128.650 113.699 1.00 166.80 ?  45  ASN A OD1 1 
ATOM   307  N ND2 . ASN A 1 38  ? 119.738 129.523 112.233 1.00 168.10 ?  45  ASN A ND2 1 
ATOM   308  N N   . GLY A 1 39  ? 116.771 128.137 116.513 1.00 173.63 ?  46  GLY A N   1 
ATOM   309  C CA  . GLY A 1 39  ? 115.920 128.285 117.679 1.00 173.43 ?  46  GLY A CA  1 
ATOM   310  C C   . GLY A 1 39  ? 116.237 127.259 118.747 1.00 174.46 ?  46  GLY A C   1 
ATOM   311  O O   . GLY A 1 39  ? 116.360 127.591 119.929 1.00 174.86 ?  46  GLY A O   1 
ATOM   312  N N   . LEU A 1 40  ? 116.403 125.998 118.339 1.00 174.73 ?  47  LEU A N   1 
ATOM   313  C CA  . LEU A 1 40  ? 116.742 124.955 119.300 1.00 176.26 ?  47  LEU A CA  1 
ATOM   314  C C   . LEU A 1 40  ? 118.091 125.228 119.955 1.00 177.52 ?  47  LEU A C   1 
ATOM   315  O O   . LEU A 1 40  ? 118.234 125.118 121.179 1.00 175.18 ?  47  LEU A O   1 
ATOM   316  C CB  . LEU A 1 40  ? 116.741 123.591 118.611 1.00 175.29 ?  47  LEU A CB  1 
ATOM   317  C CG  . LEU A 1 40  ? 116.811 122.371 119.531 1.00 175.07 ?  47  LEU A CG  1 
ATOM   318  C CD1 . LEU A 1 40  ? 115.872 122.539 120.715 1.00 173.44 ?  47  LEU A CD1 1 
ATOM   319  C CD2 . LEU A 1 40  ? 116.488 121.100 118.761 1.00 173.70 ?  47  LEU A CD2 1 
ATOM   320  N N   . ALA A 1 41  ? 119.093 125.599 119.153 1.00 175.25 ?  48  ALA A N   1 
ATOM   321  C CA  . ALA A 1 41  ? 120.427 125.840 119.693 1.00 173.14 ?  48  ALA A CA  1 
ATOM   322  C C   . ALA A 1 41  ? 120.437 127.030 120.644 1.00 173.35 ?  48  ALA A C   1 
ATOM   323  O O   . ALA A 1 41  ? 121.060 126.976 121.710 1.00 174.38 ?  48  ALA A O   1 
ATOM   324  C CB  . ALA A 1 41  ? 121.422 126.056 118.553 1.00 172.34 ?  48  ALA A CB  1 
ATOM   325  N N   . LEU A 1 42  ? 119.750 128.113 120.277 1.00 168.74 ?  49  LEU A N   1 
ATOM   326  C CA  . LEU A 1 42  ? 119.705 129.289 121.135 1.00 170.69 ?  49  LEU A CA  1 
ATOM   327  C C   . LEU A 1 42  ? 118.950 129.001 122.427 1.00 171.44 ?  49  LEU A C   1 
ATOM   328  O O   . LEU A 1 42  ? 119.356 129.459 123.501 1.00 169.13 ?  49  LEU A O   1 
ATOM   329  C CB  . LEU A 1 42  ? 119.076 130.459 120.380 1.00 170.16 ?  49  LEU A CB  1 
ATOM   330  C CG  . LEU A 1 42  ? 120.025 131.205 119.437 1.00 168.61 ?  49  LEU A CG  1 
ATOM   331  C CD1 . LEU A 1 42  ? 119.284 131.759 118.230 1.00 166.59 ?  49  LEU A CD1 1 
ATOM   332  C CD2 . LEU A 1 42  ? 120.745 132.316 120.179 1.00 167.12 ?  49  LEU A CD2 1 
ATOM   333  N N   . TRP A 1 43  ? 117.856 128.236 122.348 1.00 179.14 ?  50  TRP A N   1 
ATOM   334  C CA  . TRP A 1 43  ? 117.146 127.853 123.562 1.00 178.29 ?  50  TRP A CA  1 
ATOM   335  C C   . TRP A 1 43  ? 118.026 127.005 124.469 1.00 178.72 ?  50  TRP A C   1 
ATOM   336  O O   . TRP A 1 43  ? 118.060 127.217 125.688 1.00 179.38 ?  50  TRP A O   1 
ATOM   337  C CB  . TRP A 1 43  ? 115.862 127.102 123.208 1.00 178.43 ?  50  TRP A CB  1 
ATOM   338  C CG  . TRP A 1 43  ? 114.950 126.899 124.379 1.00 180.42 ?  50  TRP A CG  1 
ATOM   339  C CD1 . TRP A 1 43  ? 113.890 127.679 124.735 1.00 178.50 ?  50  TRP A CD1 1 
ATOM   340  C CD2 . TRP A 1 43  ? 115.016 125.845 125.349 1.00 181.45 ?  50  TRP A CD2 1 
ATOM   341  N NE1 . TRP A 1 43  ? 113.294 127.179 125.867 1.00 179.62 ?  50  TRP A NE1 1 
ATOM   342  C CE2 . TRP A 1 43  ? 113.966 126.054 126.264 1.00 180.29 ?  50  TRP A CE2 1 
ATOM   343  C CE3 . TRP A 1 43  ? 115.862 124.747 125.533 1.00 180.07 ?  50  TRP A CE3 1 
ATOM   344  C CZ2 . TRP A 1 43  ? 113.738 125.205 127.344 1.00 178.97 ?  50  TRP A CZ2 1 
ATOM   345  C CZ3 . TRP A 1 43  ? 115.635 123.907 126.607 1.00 177.60 ?  50  TRP A CZ3 1 
ATOM   346  C CH2 . TRP A 1 43  ? 114.582 124.140 127.498 1.00 178.02 ?  50  TRP A CH2 1 
ATOM   347  N N   . ILE A 1 44  ? 118.752 126.043 123.893 1.00 172.51 ?  51  ILE A N   1 
ATOM   348  C CA  . ILE A 1 44  ? 119.628 125.196 124.696 1.00 173.98 ?  51  ILE A CA  1 
ATOM   349  C C   . ILE A 1 44  ? 120.721 126.031 125.347 1.00 174.14 ?  51  ILE A C   1 
ATOM   350  O O   . ILE A 1 44  ? 121.067 125.829 126.517 1.00 173.94 ?  51  ILE A O   1 
ATOM   351  C CB  . ILE A 1 44  ? 120.216 124.063 123.835 1.00 173.79 ?  51  ILE A CB  1 
ATOM   352  C CG1 . ILE A 1 44  ? 119.123 123.071 123.437 1.00 172.16 ?  51  ILE A CG1 1 
ATOM   353  C CG2 . ILE A 1 44  ? 121.325 123.342 124.582 1.00 173.00 ?  51  ILE A CG2 1 
ATOM   354  C CD1 . ILE A 1 44  ? 119.456 122.260 122.206 1.00 170.89 ?  51  ILE A CD1 1 
ATOM   355  N N   . PHE A 1 45  ? 121.279 126.987 124.603 1.00 170.16 ?  52  PHE A N   1 
ATOM   356  C CA  . PHE A 1 45  ? 122.361 127.800 125.146 1.00 170.06 ?  52  PHE A CA  1 
ATOM   357  C C   . PHE A 1 45  ? 121.862 128.762 126.216 1.00 170.47 ?  52  PHE A C   1 
ATOM   358  O O   . PHE A 1 45  ? 122.597 129.068 127.162 1.00 169.87 ?  52  PHE A O   1 
ATOM   359  C CB  . PHE A 1 45  ? 123.054 128.566 124.019 1.00 168.34 ?  52  PHE A CB  1 
ATOM   360  C CG  . PHE A 1 45  ? 124.028 127.736 123.225 1.00 169.80 ?  52  PHE A CG  1 
ATOM   361  C CD1 . PHE A 1 45  ? 123.977 126.352 123.260 1.00 171.08 ?  52  PHE A CD1 1 
ATOM   362  C CD2 . PHE A 1 45  ? 124.988 128.342 122.435 1.00 168.39 ?  52  PHE A CD2 1 
ATOM   363  C CE1 . PHE A 1 45  ? 124.867 125.591 122.528 1.00 168.99 ?  52  PHE A CE1 1 
ATOM   364  C CE2 . PHE A 1 45  ? 125.882 127.585 121.702 1.00 168.59 ?  52  PHE A CE2 1 
ATOM   365  C CZ  . PHE A 1 45  ? 125.821 126.209 121.748 1.00 167.98 ?  52  PHE A CZ  1 
ATOM   366  N N   . CYS A 1 46  ? 120.623 129.241 126.097 1.00 175.47 ?  53  CYS A N   1 
ATOM   367  C CA  . CYS A 1 46  ? 120.119 130.248 127.023 1.00 175.21 ?  53  CYS A CA  1 
ATOM   368  C C   . CYS A 1 46  ? 119.505 129.647 128.283 1.00 175.36 ?  53  CYS A C   1 
ATOM   369  O O   . CYS A 1 46  ? 119.866 130.049 129.394 1.00 174.22 ?  53  CYS A O   1 
ATOM   370  C CB  . CYS A 1 46  ? 119.089 131.134 126.320 1.00 173.85 ?  53  CYS A CB  1 
ATOM   371  S SG  . CYS A 1 46  ? 119.794 132.275 125.108 1.00 172.77 ?  53  CYS A SG  1 
ATOM   372  N N   . PHE A 1 47  ? 118.585 128.692 128.141 1.00 178.65 ?  54  PHE A N   1 
ATOM   373  C CA  . PHE A 1 47  ? 117.851 128.159 129.284 1.00 177.27 ?  54  PHE A CA  1 
ATOM   374  C C   . PHE A 1 47  ? 118.276 126.747 129.668 1.00 175.47 ?  54  PHE A C   1 
ATOM   375  O O   . PHE A 1 47  ? 117.605 126.116 130.493 1.00 175.19 ?  54  PHE A O   1 
ATOM   376  C CB  . PHE A 1 47  ? 116.344 128.192 129.007 1.00 176.25 ?  54  PHE A CB  1 
ATOM   377  C CG  . PHE A 1 47  ? 115.865 129.485 128.411 1.00 177.56 ?  54  PHE A CG  1 
ATOM   378  C CD1 . PHE A 1 47  ? 116.034 130.681 129.088 1.00 176.65 ?  54  PHE A CD1 1 
ATOM   379  C CD2 . PHE A 1 47  ? 115.246 129.504 127.172 1.00 175.98 ?  54  PHE A CD2 1 
ATOM   380  C CE1 . PHE A 1 47  ? 115.594 131.872 128.542 1.00 175.19 ?  54  PHE A CE1 1 
ATOM   381  C CE2 . PHE A 1 47  ? 114.803 130.692 126.620 1.00 175.06 ?  54  PHE A CE2 1 
ATOM   382  C CZ  . PHE A 1 47  ? 114.978 131.877 127.306 1.00 174.90 ?  54  PHE A CZ  1 
ATOM   383  N N   . HIS A 1 48  ? 119.362 126.230 129.097 1.00 177.27 ?  55  HIS A N   1 
ATOM   384  C CA  . HIS A 1 48  ? 119.846 124.900 129.458 1.00 179.11 ?  55  HIS A CA  1 
ATOM   385  C C   . HIS A 1 48  ? 121.348 124.826 129.701 1.00 179.54 ?  55  HIS A C   1 
ATOM   386  O O   . HIS A 1 48  ? 121.785 123.932 130.435 1.00 178.32 ?  55  HIS A O   1 
ATOM   387  C CB  . HIS A 1 48  ? 119.453 123.883 128.373 1.00 180.17 ?  55  HIS A CB  1 
ATOM   388  C CG  . HIS A 1 48  ? 120.154 122.562 128.477 1.00 181.19 ?  55  HIS A CG  1 
ATOM   389  N ND1 . HIS A 1 48  ? 121.448 122.366 128.044 1.00 180.08 ?  55  HIS A ND1 1 
ATOM   390  C CD2 . HIS A 1 48  ? 119.735 121.368 128.959 1.00 178.98 ?  55  HIS A CD2 1 
ATOM   391  C CE1 . HIS A 1 48  ? 121.798 121.111 128.260 1.00 178.37 ?  55  HIS A CE1 1 
ATOM   392  N NE2 . HIS A 1 48  ? 120.776 120.484 128.813 1.00 177.73 ?  55  HIS A NE2 1 
ATOM   393  N N   . LEU A 1 49  ? 122.153 125.731 129.150 1.00 173.78 ?  56  LEU A N   1 
ATOM   394  C CA  . LEU A 1 49  ? 123.609 125.673 129.266 1.00 173.76 ?  56  LEU A CA  1 
ATOM   395  C C   . LEU A 1 49  ? 124.056 126.627 130.369 1.00 173.70 ?  56  LEU A C   1 
ATOM   396  O O   . LEU A 1 49  ? 124.043 127.848 130.194 1.00 171.45 ?  56  LEU A O   1 
ATOM   397  C CB  . LEU A 1 49  ? 124.267 126.018 127.934 1.00 173.81 ?  56  LEU A CB  1 
ATOM   398  C CG  . LEU A 1 49  ? 125.781 125.817 127.857 1.00 174.00 ?  56  LEU A CG  1 
ATOM   399  C CD1 . LEU A 1 49  ? 126.111 124.441 127.298 1.00 171.51 ?  56  LEU A CD1 1 
ATOM   400  C CD2 . LEU A 1 49  ? 126.426 126.915 127.026 1.00 171.58 ?  56  LEU A CD2 1 
ATOM   401  N N   . LYS A 1 50  ? 124.456 126.066 131.508 1.00 166.83 ?  57  LYS A N   1 
ATOM   402  C CA  . LYS A 1 50  ? 124.953 126.857 132.625 1.00 166.16 ?  57  LYS A CA  1 
ATOM   403  C C   . LYS A 1 50  ? 126.473 126.863 132.729 1.00 165.22 ?  57  LYS A C   1 
ATOM   404  O O   . LYS A 1 50  ? 127.013 127.533 133.616 1.00 163.92 ?  57  LYS A O   1 
ATOM   405  C CB  . LYS A 1 50  ? 124.354 126.342 133.938 1.00 164.28 ?  57  LYS A CB  1 
ATOM   406  C CG  . LYS A 1 50  ? 124.249 124.829 134.015 1.00 163.50 ?  57  LYS A CG  1 
ATOM   407  C CD  . LYS A 1 50  ? 123.021 124.396 134.797 1.00 162.86 ?  57  LYS A CD  1 
ATOM   408  C CE  . LYS A 1 50  ? 123.235 123.039 135.445 1.00 163.10 ?  57  LYS A CE  1 
ATOM   409  N NZ  . LYS A 1 50  ? 123.380 121.956 134.435 1.00 163.31 1  57  LYS A NZ  1 
ATOM   410  N N   . SER A 1 51  ? 127.174 126.141 131.853 1.00 168.54 ?  58  SER A N   1 
ATOM   411  C CA  . SER A 1 51  ? 128.631 126.093 131.921 1.00 167.84 ?  58  SER A CA  1 
ATOM   412  C C   . SER A 1 51  ? 129.249 127.371 131.366 1.00 168.48 ?  58  SER A C   1 
ATOM   413  O O   . SER A 1 51  ? 129.965 128.089 132.074 1.00 166.57 ?  58  SER A O   1 
ATOM   414  C CB  . SER A 1 51  ? 129.148 124.867 131.166 1.00 166.08 ?  58  SER A CB  1 
ATOM   415  O OG  . SER A 1 51  ? 128.621 124.823 129.852 1.00 166.72 ?  58  SER A OG  1 
ATOM   416  N N   . TRP A 1 52  ? 128.983 127.664 130.092 1.00 161.66 ?  59  TRP A N   1 
ATOM   417  C CA  . TRP A 1 52  ? 129.432 128.892 129.435 1.00 160.27 ?  59  TRP A CA  1 
ATOM   418  C C   . TRP A 1 52  ? 130.958 129.021 129.462 1.00 160.84 ?  59  TRP A C   1 
ATOM   419  O O   . TRP A 1 52  ? 131.524 129.927 130.076 1.00 158.13 ?  59  TRP A O   1 
ATOM   420  C CB  . TRP A 1 52  ? 128.762 130.121 130.059 1.00 160.18 ?  59  TRP A CB  1 
ATOM   421  C CG  . TRP A 1 52  ? 127.398 130.426 129.507 1.00 160.45 ?  59  TRP A CG  1 
ATOM   422  C CD1 . TRP A 1 52  ? 126.258 130.642 130.225 1.00 160.15 ?  59  TRP A CD1 1 
ATOM   423  C CD2 . TRP A 1 52  ? 127.032 130.560 128.126 1.00 162.40 ?  59  TRP A CD2 1 
ATOM   424  N NE1 . TRP A 1 52  ? 125.205 130.894 129.380 1.00 161.63 ?  59  TRP A NE1 1 
ATOM   425  C CE2 . TRP A 1 52  ? 125.654 130.851 128.087 1.00 163.92 ?  59  TRP A CE2 1 
ATOM   426  C CE3 . TRP A 1 52  ? 127.733 130.461 126.921 1.00 160.20 ?  59  TRP A CE3 1 
ATOM   427  C CZ2 . TRP A 1 52  ? 124.966 131.044 126.891 1.00 160.47 ?  59  TRP A CZ2 1 
ATOM   428  C CZ3 . TRP A 1 52  ? 127.047 130.651 125.736 1.00 159.61 ?  59  TRP A CZ3 1 
ATOM   429  C CH2 . TRP A 1 52  ? 125.678 130.940 125.729 1.00 157.96 ?  59  TRP A CH2 1 
ATOM   430  N N   . LYS A 1 53  ? 131.618 128.086 128.787 1.00 145.94 ?  60  LYS A N   1 
ATOM   431  C CA  . LYS A 1 53  ? 133.051 128.167 128.553 1.00 141.86 ?  60  LYS A CA  1 
ATOM   432  C C   . LYS A 1 53  ? 133.329 129.005 127.308 1.00 143.19 ?  60  LYS A C   1 
ATOM   433  O O   . LYS A 1 53  ? 132.448 129.233 126.479 1.00 144.24 ?  60  LYS A O   1 
ATOM   434  C CB  . LYS A 1 53  ? 133.653 126.772 128.397 1.00 143.08 ?  60  LYS A CB  1 
ATOM   435  C CG  . LYS A 1 53  ? 133.098 125.752 129.374 1.00 143.84 ?  60  LYS A CG  1 
ATOM   436  C CD  . LYS A 1 53  ? 133.539 126.056 130.796 1.00 142.71 ?  60  LYS A CD  1 
ATOM   437  C CE  . LYS A 1 53  ? 134.814 125.312 131.148 1.00 142.29 ?  60  LYS A CE  1 
ATOM   438  N NZ  . LYS A 1 53  ? 134.585 123.846 131.265 1.00 142.60 1  60  LYS A NZ  1 
ATOM   439  N N   . SER A 1 54  ? 134.584 129.449 127.177 1.00 135.00 ?  61  SER A N   1 
ATOM   440  C CA  . SER A 1 54  ? 134.949 130.359 126.093 1.00 136.21 ?  61  SER A CA  1 
ATOM   441  C C   . SER A 1 54  ? 134.568 129.795 124.729 1.00 135.88 ?  61  SER A C   1 
ATOM   442  O O   . SER A 1 54  ? 134.039 130.515 123.871 1.00 136.94 ?  61  SER A O   1 
ATOM   443  C CB  . SER A 1 54  ? 136.447 130.655 126.145 1.00 133.11 ?  61  SER A CB  1 
ATOM   444  O OG  . SER A 1 54  ? 136.839 131.054 127.445 1.00 133.64 ?  61  SER A OG  1 
ATOM   445  N N   . SER A 1 55  ? 134.822 128.504 124.513 1.00 129.14 ?  62  SER A N   1 
ATOM   446  C CA  . SER A 1 55  ? 134.395 127.871 123.273 1.00 126.65 ?  62  SER A CA  1 
ATOM   447  C C   . SER A 1 55  ? 132.883 127.933 123.124 1.00 130.33 ?  62  SER A C   1 
ATOM   448  O O   . SER A 1 55  ? 132.367 128.120 122.017 1.00 137.09 ?  62  SER A O   1 
ATOM   449  C CB  . SER A 1 55  ? 134.881 126.425 123.227 1.00 127.92 ?  62  SER A CB  1 
ATOM   450  O OG  . SER A 1 55  ? 136.256 126.344 123.553 1.00 128.75 ?  62  SER A OG  1 
ATOM   451  N N   . ARG A 1 56  ? 132.154 127.790 124.232 1.00 139.19 ?  63  ARG A N   1 
ATOM   452  C CA  . ARG A 1 56  ? 130.703 127.910 124.175 1.00 139.40 ?  63  ARG A CA  1 
ATOM   453  C C   . ARG A 1 56  ? 130.278 129.339 123.862 1.00 138.23 ?  63  ARG A C   1 
ATOM   454  O O   . ARG A 1 56  ? 129.283 129.550 123.164 1.00 138.62 ?  63  ARG A O   1 
ATOM   455  C CB  . ARG A 1 56  ? 130.083 127.430 125.486 1.00 140.27 ?  63  ARG A CB  1 
ATOM   456  C CG  . ARG A 1 56  ? 130.387 125.979 125.806 1.00 138.16 ?  63  ARG A CG  1 
ATOM   457  C CD  . ARG A 1 56  ? 129.193 125.095 125.501 1.00 141.53 ?  63  ARG A CD  1 
ATOM   458  N NE  . ARG A 1 56  ? 129.233 124.558 124.147 1.00 144.87 ?  63  ARG A NE  1 
ATOM   459  C CZ  . ARG A 1 56  ? 129.566 123.311 123.846 1.00 143.85 ?  63  ARG A CZ  1 
ATOM   460  N NH1 . ARG A 1 56  ? 129.906 122.441 124.783 1.00 139.40 1  63  ARG A NH1 1 
ATOM   461  N NH2 . ARG A 1 56  ? 129.555 122.926 122.573 1.00 140.92 ?  63  ARG A NH2 1 
ATOM   462  N N   . ILE A 1 57  ? 131.017 130.334 124.358 1.00 126.48 ?  64  ILE A N   1 
ATOM   463  C CA  . ILE A 1 57  ? 130.733 131.722 123.991 1.00 128.82 ?  64  ILE A CA  1 
ATOM   464  C C   . ILE A 1 57  ? 130.899 131.923 122.489 1.00 129.68 ?  64  ILE A C   1 
ATOM   465  O O   . ILE A 1 57  ? 130.054 132.544 121.831 1.00 130.03 ?  64  ILE A O   1 
ATOM   466  C CB  . ILE A 1 57  ? 131.619 132.694 124.794 1.00 129.92 ?  64  ILE A CB  1 
ATOM   467  C CG1 . ILE A 1 57  ? 131.033 132.978 126.183 1.00 129.84 ?  64  ILE A CG1 1 
ATOM   468  C CG2 . ILE A 1 57  ? 131.826 133.993 124.033 1.00 128.69 ?  64  ILE A CG2 1 
ATOM   469  C CD1 . ILE A 1 57  ? 131.039 131.832 127.147 1.00 129.94 ?  64  ILE A CD1 1 
ATOM   470  N N   . PHE A 1 58  ? 131.991 131.404 121.924 1.00 119.74 ?  65  PHE A N   1 
ATOM   471  C CA  . PHE A 1 58  ? 132.211 131.561 120.489 1.00 117.09 ?  65  PHE A CA  1 
ATOM   472  C C   . PHE A 1 58  ? 131.150 130.824 119.678 1.00 117.35 ?  65  PHE A C   1 
ATOM   473  O O   . PHE A 1 58  ? 130.669 131.336 118.657 1.00 120.37 ?  65  PHE A O   1 
ATOM   474  C CB  . PHE A 1 58  ? 133.612 131.081 120.120 1.00 116.10 ?  65  PHE A CB  1 
ATOM   475  C CG  . PHE A 1 58  ? 134.709 131.878 120.761 1.00 117.25 ?  65  PHE A CG  1 
ATOM   476  C CD1 . PHE A 1 58  ? 134.677 133.260 120.740 1.00 114.83 ?  65  PHE A CD1 1 
ATOM   477  C CD2 . PHE A 1 58  ? 135.767 131.249 121.387 1.00 119.72 ?  65  PHE A CD2 1 
ATOM   478  C CE1 . PHE A 1 58  ? 135.679 133.998 121.329 1.00 117.91 ?  65  PHE A CE1 1 
ATOM   479  C CE2 . PHE A 1 58  ? 136.772 131.983 121.980 1.00 118.58 ?  65  PHE A CE2 1 
ATOM   480  C CZ  . PHE A 1 58  ? 136.728 133.359 121.950 1.00 119.59 ?  65  PHE A CZ  1 
ATOM   481  N N   . LEU A 1 59  ? 130.767 129.625 120.118 1.00 126.08 ?  66  LEU A N   1 
ATOM   482  C CA  . LEU A 1 59  ? 129.718 128.885 119.425 1.00 128.65 ?  66  LEU A CA  1 
ATOM   483  C C   . LEU A 1 59  ? 128.377 129.603 119.520 1.00 133.41 ?  66  LEU A C   1 
ATOM   484  O O   . LEU A 1 59  ? 127.601 129.610 118.559 1.00 134.87 ?  66  LEU A O   1 
ATOM   485  C CB  . LEU A 1 59  ? 129.621 127.471 119.991 1.00 130.09 ?  66  LEU A CB  1 
ATOM   486  C CG  . LEU A 1 59  ? 130.781 126.550 119.615 1.00 128.33 ?  66  LEU A CG  1 
ATOM   487  C CD1 . LEU A 1 59  ? 130.955 125.456 120.651 1.00 128.85 ?  66  LEU A CD1 1 
ATOM   488  C CD2 . LEU A 1 59  ? 130.563 125.956 118.237 1.00 127.01 ?  66  LEU A CD2 1 
ATOM   489  N N   . PHE A 1 60  ? 128.088 130.218 120.668 1.00 136.43 ?  67  PHE A N   1 
ATOM   490  C CA  . PHE A 1 60  ? 126.868 131.005 120.807 1.00 136.09 ?  67  PHE A CA  1 
ATOM   491  C C   . PHE A 1 60  ? 126.879 132.209 119.876 1.00 133.89 ?  67  PHE A C   1 
ATOM   492  O O   . PHE A 1 60  ? 125.852 132.550 119.279 1.00 133.26 ?  67  PHE A O   1 
ATOM   493  C CB  . PHE A 1 60  ? 126.702 131.451 122.258 1.00 140.76 ?  67  PHE A CB  1 
ATOM   494  C CG  . PHE A 1 60  ? 125.544 132.379 122.479 1.00 143.05 ?  67  PHE A CG  1 
ATOM   495  C CD1 . PHE A 1 60  ? 124.246 131.902 122.472 1.00 140.41 ?  67  PHE A CD1 1 
ATOM   496  C CD2 . PHE A 1 60  ? 125.757 133.730 122.693 1.00 138.74 ?  67  PHE A CD2 1 
ATOM   497  C CE1 . PHE A 1 60  ? 123.181 132.756 122.673 1.00 139.79 ?  67  PHE A CE1 1 
ATOM   498  C CE2 . PHE A 1 60  ? 124.698 134.588 122.894 1.00 135.74 ?  67  PHE A CE2 1 
ATOM   499  C CZ  . PHE A 1 60  ? 123.407 134.101 122.884 1.00 140.03 ?  67  PHE A CZ  1 
ATOM   500  N N   . ASN A 1 61  ? 128.026 132.878 119.757 1.00 116.74 ?  68  ASN A N   1 
ATOM   501  C CA  . ASN A 1 61  ? 128.127 134.005 118.836 1.00 113.03 ?  68  ASN A CA  1 
ATOM   502  C C   . ASN A 1 61  ? 127.890 133.559 117.401 1.00 114.53 ?  68  ASN A C   1 
ATOM   503  O O   . ASN A 1 61  ? 127.188 134.233 116.636 1.00 120.47 ?  68  ASN A O   1 
ATOM   504  C CB  . ASN A 1 61  ? 129.493 134.668 118.969 1.00 111.45 ?  68  ASN A CB  1 
ATOM   505  C CG  . ASN A 1 61  ? 129.571 135.603 120.149 1.00 115.07 ?  68  ASN A CG  1 
ATOM   506  O OD1 . ASN A 1 61  ? 129.577 136.821 119.989 1.00 115.90 ?  68  ASN A OD1 1 
ATOM   507  N ND2 . ASN A 1 61  ? 129.634 135.038 121.348 1.00 117.16 ?  68  ASN A ND2 1 
ATOM   508  N N   . LEU A 1 62  ? 128.466 132.417 117.021 1.00 117.82 ?  69  LEU A N   1 
ATOM   509  C CA  . LEU A 1 62  ? 128.198 131.863 115.699 1.00 118.18 ?  69  LEU A CA  1 
ATOM   510  C C   . LEU A 1 62  ? 126.715 131.563 115.526 1.00 120.06 ?  69  LEU A C   1 
ATOM   511  O O   . LEU A 1 62  ? 126.145 131.794 114.452 1.00 118.39 ?  69  LEU A O   1 
ATOM   512  C CB  . LEU A 1 62  ? 129.032 130.601 115.485 1.00 116.79 ?  69  LEU A CB  1 
ATOM   513  C CG  . LEU A 1 62  ? 128.729 129.773 114.238 1.00 115.06 ?  69  LEU A CG  1 
ATOM   514  C CD1 . LEU A 1 62  ? 128.917 130.608 112.992 1.00 121.38 ?  69  LEU A CD1 1 
ATOM   515  C CD2 . LEU A 1 62  ? 129.611 128.544 114.196 1.00 113.94 ?  69  LEU A CD2 1 
ATOM   516  N N   . ALA A 1 63  ? 126.074 131.051 116.578 1.00 133.81 ?  70  ALA A N   1 
ATOM   517  C CA  . ALA A 1 63  ? 124.653 130.729 116.511 1.00 135.10 ?  70  ALA A CA  1 
ATOM   518  C C   . ALA A 1 63  ? 123.809 131.976 116.281 1.00 135.14 ?  70  ALA A C   1 
ATOM   519  O O   . ALA A 1 63  ? 122.890 131.971 115.456 1.00 134.58 ?  70  ALA A O   1 
ATOM   520  C CB  . ALA A 1 63  ? 124.222 130.015 117.792 1.00 134.29 ?  70  ALA A CB  1 
ATOM   521  N N   . VAL A 1 64  ? 124.100 133.057 117.007 1.00 127.08 ?  71  VAL A N   1 
ATOM   522  C CA  . VAL A 1 64  ? 123.315 134.277 116.828 1.00 128.37 ?  71  VAL A CA  1 
ATOM   523  C C   . VAL A 1 64  ? 123.582 134.893 115.458 1.00 128.09 ?  71  VAL A C   1 
ATOM   524  O O   . VAL A 1 64  ? 122.671 135.445 114.828 1.00 128.87 ?  71  VAL A O   1 
ATOM   525  C CB  . VAL A 1 64  ? 123.557 135.282 117.974 1.00 130.46 ?  71  VAL A CB  1 
ATOM   526  C CG1 . VAL A 1 64  ? 123.568 134.574 119.314 1.00 130.59 ?  71  VAL A CG1 1 
ATOM   527  C CG2 . VAL A 1 64  ? 124.840 136.071 117.774 1.00 128.00 ?  71  VAL A CG2 1 
ATOM   528  N N   . ALA A 1 65  ? 124.820 134.798 114.964 1.00 130.02 ?  72  ALA A N   1 
ATOM   529  C CA  . ALA A 1 65  ? 125.104 135.300 113.624 1.00 125.83 ?  72  ALA A CA  1 
ATOM   530  C C   . ALA A 1 65  ? 124.317 134.527 112.575 1.00 127.17 ?  72  ALA A C   1 
ATOM   531  O O   . ALA A 1 65  ? 123.724 135.122 111.666 1.00 130.56 ?  72  ALA A O   1 
ATOM   532  C CB  . ALA A 1 65  ? 126.602 135.224 113.339 1.00 127.67 ?  72  ALA A CB  1 
ATOM   533  N N   . ASP A 1 66  ? 124.285 133.199 112.696 1.00 136.84 ?  73  ASP A N   1 
ATOM   534  C CA  . ASP A 1 66  ? 123.500 132.389 111.771 1.00 138.93 ?  73  ASP A CA  1 
ATOM   535  C C   . ASP A 1 66  ? 122.016 132.710 111.880 1.00 143.13 ?  73  ASP A C   1 
ATOM   536  O O   . ASP A 1 66  ? 121.310 132.787 110.866 1.00 144.40 ?  73  ASP A O   1 
ATOM   537  C CB  . ASP A 1 66  ? 123.745 130.906 112.037 1.00 141.03 ?  73  ASP A CB  1 
ATOM   538  C CG  . ASP A 1 66  ? 125.039 130.411 111.430 1.00 144.94 ?  73  ASP A CG  1 
ATOM   539  O OD1 . ASP A 1 66  ? 125.343 130.796 110.282 1.00 146.95 ?  73  ASP A OD1 1 
ATOM   540  O OD2 . ASP A 1 66  ? 125.751 129.634 112.098 1.00 144.57 -1 73  ASP A OD2 1 
ATOM   541  N N   . PHE A 1 67  ? 121.523 132.899 113.106 1.00 151.13 ?  74  PHE A N   1 
ATOM   542  C CA  . PHE A 1 67  ? 120.110 133.197 113.303 1.00 151.17 ?  74  PHE A CA  1 
ATOM   543  C C   . PHE A 1 67  ? 119.728 134.515 112.647 1.00 149.14 ?  74  PHE A C   1 
ATOM   544  O O   . PHE A 1 67  ? 118.674 134.614 112.013 1.00 147.26 ?  74  PHE A O   1 
ATOM   545  C CB  . PHE A 1 67  ? 119.785 133.225 114.795 1.00 152.00 ?  74  PHE A CB  1 
ATOM   546  C CG  . PHE A 1 67  ? 118.348 133.543 115.097 1.00 155.50 ?  74  PHE A CG  1 
ATOM   547  C CD1 . PHE A 1 67  ? 117.352 132.614 114.846 1.00 155.28 ?  74  PHE A CD1 1 
ATOM   548  C CD2 . PHE A 1 67  ? 117.995 134.769 115.634 1.00 150.78 ?  74  PHE A CD2 1 
ATOM   549  C CE1 . PHE A 1 67  ? 116.031 132.903 115.123 1.00 151.83 ?  74  PHE A CE1 1 
ATOM   550  C CE2 . PHE A 1 67  ? 116.675 135.063 115.913 1.00 149.52 ?  74  PHE A CE2 1 
ATOM   551  C CZ  . PHE A 1 67  ? 115.693 134.128 115.657 1.00 150.44 ?  74  PHE A CZ  1 
ATOM   552  N N   . LEU A 1 68  ? 120.567 135.540 112.795 1.00 138.99 ?  75  LEU A N   1 
ATOM   553  C CA  . LEU A 1 68  ? 120.297 136.815 112.136 1.00 137.22 ?  75  LEU A CA  1 
ATOM   554  C C   . LEU A 1 68  ? 120.344 136.663 110.619 1.00 135.80 ?  75  LEU A C   1 
ATOM   555  O O   . LEU A 1 68  ? 119.449 137.135 109.900 1.00 138.38 ?  75  LEU A O   1 
ATOM   556  C CB  . LEU A 1 68  ? 121.301 137.866 112.605 1.00 138.33 ?  75  LEU A CB  1 
ATOM   557  C CG  . LEU A 1 68  ? 120.933 138.753 113.797 1.00 139.38 ?  75  LEU A CG  1 
ATOM   558  C CD1 . LEU A 1 68  ? 120.443 137.926 114.972 1.00 137.28 ?  75  LEU A CD1 1 
ATOM   559  C CD2 . LEU A 1 68  ? 122.123 139.606 114.206 1.00 136.71 ?  75  LEU A CD2 1 
ATOM   560  N N   . LEU A 1 69  ? 121.380 135.985 110.116 1.00 136.88 ?  76  LEU A N   1 
ATOM   561  C CA  . LEU A 1 69  ? 121.513 135.785 108.678 1.00 137.62 ?  76  LEU A CA  1 
ATOM   562  C C   . LEU A 1 69  ? 120.310 135.054 108.104 1.00 139.60 ?  76  LEU A C   1 
ATOM   563  O O   . LEU A 1 69  ? 119.956 135.263 106.939 1.00 141.58 ?  76  LEU A O   1 
ATOM   564  C CB  . LEU A 1 69  ? 122.801 135.016 108.375 1.00 137.77 ?  76  LEU A CB  1 
ATOM   565  C CG  . LEU A 1 69  ? 123.304 134.921 106.930 1.00 138.27 ?  76  LEU A CG  1 
ATOM   566  C CD1 . LEU A 1 69  ? 122.733 133.715 106.200 1.00 138.56 ?  76  LEU A CD1 1 
ATOM   567  C CD2 . LEU A 1 69  ? 122.993 136.192 106.174 1.00 140.07 ?  76  LEU A CD2 1 
ATOM   568  N N   . ILE A 1 70  ? 119.670 134.197 108.895 1.00 149.79 ?  77  ILE A N   1 
ATOM   569  C CA  . ILE A 1 70  ? 118.538 133.452 108.362 1.00 150.08 ?  77  ILE A CA  1 
ATOM   570  C C   . ILE A 1 70  ? 117.198 134.152 108.592 1.00 151.86 ?  77  ILE A C   1 
ATOM   571  O O   . ILE A 1 70  ? 116.280 133.995 107.782 1.00 150.43 ?  77  ILE A O   1 
ATOM   572  C CB  . ILE A 1 70  ? 118.514 132.020 108.915 1.00 149.44 ?  77  ILE A CB  1 
ATOM   573  C CG1 . ILE A 1 70  ? 117.699 131.142 107.970 1.00 150.72 ?  77  ILE A CG1 1 
ATOM   574  C CG2 . ILE A 1 70  ? 117.973 131.983 110.334 1.00 149.77 ?  77  ILE A CG2 1 
ATOM   575  C CD1 . ILE A 1 70  ? 117.354 129.818 108.521 1.00 150.48 ?  77  ILE A CD1 1 
ATOM   576  N N   . ILE A 1 71  ? 117.045 134.928 109.669 1.00 151.44 ?  78  ILE A N   1 
ATOM   577  C CA  . ILE A 1 71  ? 115.815 135.700 109.813 1.00 149.20 ?  78  ILE A CA  1 
ATOM   578  C C   . ILE A 1 71  ? 115.782 136.866 108.843 1.00 148.22 ?  78  ILE A C   1 
ATOM   579  O O   . ILE A 1 71  ? 114.722 137.469 108.646 1.00 148.03 ?  78  ILE A O   1 
ATOM   580  C CB  . ILE A 1 71  ? 115.582 136.136 111.282 1.00 148.52 ?  78  ILE A CB  1 
ATOM   581  C CG1 . ILE A 1 71  ? 116.697 137.017 111.884 1.00 149.68 ?  78  ILE A CG1 1 
ATOM   582  C CG2 . ILE A 1 71  ? 115.342 134.916 112.161 1.00 147.77 ?  78  ILE A CG2 1 
ATOM   583  C CD1 . ILE A 1 71  ? 116.921 138.398 111.284 1.00 146.35 ?  78  ILE A CD1 1 
ATOM   584  N N   . CYS A 1 72  ? 116.922 137.202 108.239 1.00 153.03 ?  79  CYS A N   1 
ATOM   585  C CA  . CYS A 1 72  ? 116.903 138.133 107.119 1.00 152.61 ?  79  CYS A CA  1 
ATOM   586  C C   . CYS A 1 72  ? 116.495 137.478 105.807 1.00 152.46 ?  79  CYS A C   1 
ATOM   587  O O   . CYS A 1 72  ? 116.277 138.191 104.823 1.00 150.87 ?  79  CYS A O   1 
ATOM   588  C CB  . CYS A 1 72  ? 118.272 138.783 106.959 1.00 153.48 ?  79  CYS A CB  1 
ATOM   589  S SG  . CYS A 1 72  ? 118.715 139.772 108.376 1.00 161.11 ?  79  CYS A SG  1 
ATOM   590  N N   . LEU A 1 73  ? 116.394 136.151 105.768 1.00 155.77 ?  80  LEU A N   1 
ATOM   591  C CA  . LEU A 1 73  ? 116.052 135.472 104.521 1.00 156.70 ?  80  LEU A CA  1 
ATOM   592  C C   . LEU A 1 73  ? 114.679 135.830 103.961 1.00 157.57 ?  80  LEU A C   1 
ATOM   593  O O   . LEU A 1 73  ? 114.590 136.033 102.739 1.00 157.34 ?  80  LEU A O   1 
ATOM   594  C CB  . LEU A 1 73  ? 116.174 133.954 104.700 1.00 155.39 ?  80  LEU A CB  1 
ATOM   595  C CG  . LEU A 1 73  ? 117.592 133.388 104.624 1.00 154.56 ?  80  LEU A CG  1 
ATOM   596  C CD1 . LEU A 1 73  ? 117.555 131.881 104.452 1.00 155.23 ?  80  LEU A CD1 1 
ATOM   597  C CD2 . LEU A 1 73  ? 118.363 134.036 103.489 1.00 156.04 ?  80  LEU A CD2 1 
ATOM   598  N N   . PRO A 1 74  ? 113.592 135.901 104.744 1.00 162.50 ?  81  PRO A N   1 
ATOM   599  C CA  . PRO A 1 74  ? 112.267 136.100 104.126 1.00 160.67 ?  81  PRO A CA  1 
ATOM   600  C C   . PRO A 1 74  ? 112.140 137.364 103.289 1.00 160.76 ?  81  PRO A C   1 
ATOM   601  O O   . PRO A 1 74  ? 111.385 137.363 102.310 1.00 159.11 ?  81  PRO A O   1 
ATOM   602  C CB  . PRO A 1 74  ? 111.315 136.130 105.332 1.00 160.33 ?  81  PRO A CB  1 
ATOM   603  C CG  . PRO A 1 74  ? 112.185 136.365 106.517 1.00 160.42 ?  81  PRO A CG  1 
ATOM   604  C CD  . PRO A 1 74  ? 113.470 135.689 106.196 1.00 161.38 ?  81  PRO A CD  1 
ATOM   605  N N   . PHE A 1 75  ? 112.838 138.445 103.637 1.00 162.43 ?  82  PHE A N   1 
ATOM   606  C CA  . PHE A 1 75  ? 112.816 139.632 102.787 1.00 161.84 ?  82  PHE A CA  1 
ATOM   607  C C   . PHE A 1 75  ? 113.420 139.331 101.419 1.00 164.81 ?  82  PHE A C   1 
ATOM   608  O O   . PHE A 1 75  ? 112.862 139.699 100.377 1.00 165.04 ?  82  PHE A O   1 
ATOM   609  C CB  . PHE A 1 75  ? 113.567 140.777 103.468 1.00 163.57 ?  82  PHE A CB  1 
ATOM   610  C CG  . PHE A 1 75  ? 112.829 141.390 104.625 1.00 163.81 ?  82  PHE A CG  1 
ATOM   611  C CD1 . PHE A 1 75  ? 111.598 140.901 105.025 1.00 162.43 ?  82  PHE A CD1 1 
ATOM   612  C CD2 . PHE A 1 75  ? 113.374 142.461 105.315 1.00 163.91 ?  82  PHE A CD2 1 
ATOM   613  C CE1 . PHE A 1 75  ? 110.924 141.468 106.088 1.00 162.72 ?  82  PHE A CE1 1 
ATOM   614  C CE2 . PHE A 1 75  ? 112.706 143.032 106.377 1.00 162.66 ?  82  PHE A CE2 1 
ATOM   615  C CZ  . PHE A 1 75  ? 111.480 142.535 106.766 1.00 163.56 ?  82  PHE A CZ  1 
ATOM   616  N N   . LEU A 1 76  ? 114.566 138.646 101.410 1.00 170.35 ?  83  LEU A N   1 
ATOM   617  C CA  . LEU A 1 76  ? 115.168 138.198 100.160 1.00 170.01 ?  83  LEU A CA  1 
ATOM   618  C C   . LEU A 1 76  ? 114.243 137.254 99.408  1.00 169.20 ?  83  LEU A C   1 
ATOM   619  O O   . LEU A 1 76  ? 114.195 137.282 98.174  1.00 167.83 ?  83  LEU A O   1 
ATOM   620  C CB  . LEU A 1 76  ? 116.520 137.542 100.460 1.00 167.51 ?  83  LEU A CB  1 
ATOM   621  C CG  . LEU A 1 76  ? 117.528 137.160 99.370  1.00 167.48 ?  83  LEU A CG  1 
ATOM   622  C CD1 . LEU A 1 76  ? 117.116 135.893 98.652  1.00 167.53 ?  83  LEU A CD1 1 
ATOM   623  C CD2 . LEU A 1 76  ? 117.683 138.291 98.372  1.00 166.58 ?  83  LEU A CD2 1 
ATOM   624  N N   . MET A 1 77  ? 113.505 136.412 100.130 1.00 170.65 ?  84  MET A N   1 
ATOM   625  C CA  . MET A 1 77  ? 112.561 135.512 99.481  1.00 169.89 ?  84  MET A CA  1 
ATOM   626  C C   . MET A 1 77  ? 111.439 136.288 98.804  1.00 172.23 ?  84  MET A C   1 
ATOM   627  O O   . MET A 1 77  ? 111.045 135.973 97.675  1.00 172.62 ?  84  MET A O   1 
ATOM   628  C CB  . MET A 1 77  ? 111.991 134.526 100.499 1.00 168.81 ?  84  MET A CB  1 
ATOM   629  C CG  . MET A 1 77  ? 111.267 133.304 99.923  1.00 171.04 ?  84  MET A CG  1 
ATOM   630  S SD  . MET A 1 77  ? 112.164 132.253 98.750  1.00 173.09 ?  84  MET A SD  1 
ATOM   631  C CE  . MET A 1 77  ? 112.114 133.168 97.207  1.00 169.90 ?  84  MET A CE  1 
ATOM   632  N N   . ASP A 1 78  ? 110.912 137.306 99.481  1.00 172.25 ?  85  ASP A N   1 
ATOM   633  C CA  . ASP A 1 78  ? 109.867 138.129 98.886  1.00 170.67 ?  85  ASP A CA  1 
ATOM   634  C C   . ASP A 1 78  ? 110.404 138.830 97.646  1.00 169.12 ?  85  ASP A C   1 
ATOM   635  O O   . ASP A 1 78  ? 109.718 138.912 96.620  1.00 168.15 ?  85  ASP A O   1 
ATOM   636  C CB  . ASP A 1 78  ? 109.346 139.123 99.934  1.00 169.93 ?  85  ASP A CB  1 
ATOM   637  C CG  . ASP A 1 78  ? 108.262 140.070 99.408  1.00 172.06 ?  85  ASP A CG  1 
ATOM   638  O OD1 . ASP A 1 78  ? 108.096 140.253 98.186  1.00 171.00 ?  85  ASP A OD1 1 
ATOM   639  O OD2 . ASP A 1 78  ? 107.544 140.637 100.257 1.00 172.89 -1 85  ASP A OD2 1 
ATOM   640  N N   . ASN A 1 79  ? 111.649 139.308 97.711  1.00 167.73 ?  86  ASN A N   1 
ATOM   641  C CA  . ASN A 1 79  ? 112.278 139.902 96.534  1.00 168.68 ?  86  ASN A CA  1 
ATOM   642  C C   . ASN A 1 79  ? 112.343 138.893 95.392  1.00 168.20 ?  86  ASN A C   1 
ATOM   643  O O   . ASN A 1 79  ? 111.957 139.196 94.258  1.00 168.32 ?  86  ASN A O   1 
ATOM   644  C CB  . ASN A 1 79  ? 113.675 140.417 96.906  1.00 168.54 ?  86  ASN A CB  1 
ATOM   645  C CG  . ASN A 1 79  ? 114.481 140.937 95.710  1.00 168.32 ?  86  ASN A CG  1 
ATOM   646  O OD1 . ASN A 1 79  ? 114.449 140.392 94.607  1.00 167.95 ?  86  ASN A OD1 1 
ATOM   647  N ND2 . ASN A 1 79  ? 115.219 142.014 95.944  1.00 167.45 ?  86  ASN A ND2 1 
ATOM   648  N N   . TYR A 1 80  ? 112.813 137.678 95.681  1.00 171.81 ?  87  TYR A N   1 
ATOM   649  C CA  . TYR A 1 80  ? 113.062 136.707 94.620  1.00 172.69 ?  87  TYR A CA  1 
ATOM   650  C C   . TYR A 1 80  ? 111.773 136.168 94.017  1.00 172.01 ?  87  TYR A C   1 
ATOM   651  O O   . TYR A 1 80  ? 111.758 135.790 92.841  1.00 171.82 ?  87  TYR A O   1 
ATOM   652  C CB  . TYR A 1 80  ? 113.917 135.556 95.146  1.00 173.83 ?  87  TYR A CB  1 
ATOM   653  C CG  . TYR A 1 80  ? 115.402 135.811 95.044  1.00 173.17 ?  87  TYR A CG  1 
ATOM   654  C CD1 . TYR A 1 80  ? 115.884 136.995 94.511  1.00 172.68 ?  87  TYR A CD1 1 
ATOM   655  C CD2 . TYR A 1 80  ? 116.319 134.864 95.467  1.00 171.70 ?  87  TYR A CD2 1 
ATOM   656  C CE1 . TYR A 1 80  ? 117.237 137.233 94.414  1.00 173.24 ?  87  TYR A CE1 1 
ATOM   657  C CE2 . TYR A 1 80  ? 117.675 135.095 95.372  1.00 171.62 ?  87  TYR A CE2 1 
ATOM   658  C CZ  . TYR A 1 80  ? 118.128 136.279 94.845  1.00 173.07 ?  87  TYR A CZ  1 
ATOM   659  O OH  . TYR A 1 80  ? 119.480 136.506 94.749  1.00 172.66 ?  87  TYR A OH  1 
ATOM   660  N N   . VAL A 1 81  ? 110.692 136.111 94.798  1.00 174.19 ?  88  VAL A N   1 
ATOM   661  C CA  . VAL A 1 81  ? 109.414 135.650 94.259  1.00 175.87 ?  88  VAL A CA  1 
ATOM   662  C C   . VAL A 1 81  ? 108.970 136.551 93.114  1.00 176.12 ?  88  VAL A C   1 
ATOM   663  O O   . VAL A 1 81  ? 108.453 136.080 92.093  1.00 173.80 ?  88  VAL A O   1 
ATOM   664  C CB  . VAL A 1 81  ? 108.355 135.579 95.375  1.00 174.44 ?  88  VAL A CB  1 
ATOM   665  C CG1 . VAL A 1 81  ? 106.955 135.507 94.786  1.00 173.31 ?  88  VAL A CG1 1 
ATOM   666  C CG2 . VAL A 1 81  ? 108.613 134.382 96.274  1.00 171.80 ?  88  VAL A CG2 1 
ATOM   667  N N   . ARG A 1 82  ? 109.189 137.856 93.253  1.00 175.90 ?  89  ARG A N   1 
ATOM   668  C CA  . ARG A 1 82  ? 108.842 138.836 92.227  1.00 173.74 ?  89  ARG A CA  1 
ATOM   669  C C   . ARG A 1 82  ? 110.025 139.171 91.335  1.00 174.70 ?  89  ARG A C   1 
ATOM   670  O O   . ARG A 1 82  ? 110.177 140.318 90.903  1.00 175.12 ?  89  ARG A O   1 
ATOM   671  C CB  . ARG A 1 82  ? 108.287 140.093 92.886  1.00 172.88 ?  89  ARG A CB  1 
ATOM   672  C CG  . ARG A 1 82  ? 107.541 139.829 94.179  1.00 174.62 ?  89  ARG A CG  1 
ATOM   673  C CD  . ARG A 1 82  ? 106.035 139.864 93.966  1.00 174.55 ?  89  ARG A CD  1 
ATOM   674  N NE  . ARG A 1 82  ? 105.305 139.753 95.222  1.00 175.26 ?  89  ARG A NE  1 
ATOM   675  C CZ  . ARG A 1 82  ? 105.177 140.737 96.102  1.00 174.72 ?  89  ARG A CZ  1 
ATOM   676  N NH1 . ARG A 1 82  ? 105.705 141.930 95.888  1.00 173.54 1  89  ARG A NH1 1 
ATOM   677  N NH2 . ARG A 1 82  ? 104.498 140.518 97.225  1.00 173.84 ?  89  ARG A NH2 1 
ATOM   678  N N   . ARG A 1 83  ? 110.884 138.188 91.059  1.00 178.14 ?  90  ARG A N   1 
ATOM   679  C CA  . ARG A 1 83  ? 112.102 138.370 90.263  1.00 177.43 ?  90  ARG A CA  1 
ATOM   680  C C   . ARG A 1 83  ? 112.824 139.455 91.053  1.00 177.95 ?  90  ARG A C   1 
ATOM   681  O O   . ARG A 1 83  ? 113.045 139.266 92.261  1.00 179.34 ?  90  ARG A O   1 
ATOM   682  C CB  . ARG A 1 83  ? 111.731 138.706 88.817  1.00 175.97 ?  90  ARG A CB  1 
ATOM   683  C CG  . ARG A 1 83  ? 112.694 138.140 87.789  1.00 176.11 ?  90  ARG A CG  1 
ATOM   684  C CD  . ARG A 1 83  ? 112.026 137.952 86.438  1.00 177.40 ?  90  ARG A CD  1 
ATOM   685  N NE  . ARG A 1 83  ? 110.986 138.944 86.194  1.00 179.25 ?  90  ARG A NE  1 
ATOM   686  C CZ  . ARG A 1 83  ? 109.708 138.655 85.987  1.00 177.90 ?  90  ARG A CZ  1 
ATOM   687  N NH1 . ARG A 1 83  ? 109.274 137.406 85.991  1.00 176.97 1  90  ARG A NH1 1 
ATOM   688  N NH2 . ARG A 1 83  ? 108.846 139.644 85.770  1.00 176.43 ?  90  ARG A NH2 1 
ATOM   689  N N   . TRP A 1 84  ? 113.217 140.569 90.443  1.00 170.44 ?  91  TRP A N   1 
ATOM   690  C CA  . TRP A 1 84  ? 113.849 141.651 91.183  1.00 171.20 ?  91  TRP A CA  1 
ATOM   691  C C   . TRP A 1 84  ? 112.983 142.883 91.412  1.00 172.33 ?  91  TRP A C   1 
ATOM   692  O O   . TRP A 1 84  ? 113.415 144.012 91.159  1.00 173.04 ?  91  TRP A O   1 
ATOM   693  C CB  . TRP A 1 84  ? 115.112 142.007 90.399  1.00 171.06 ?  91  TRP A CB  1 
ATOM   694  C CG  . TRP A 1 84  ? 116.090 140.874 90.296  1.00 171.82 ?  91  TRP A CG  1 
ATOM   695  C CD1 . TRP A 1 84  ? 116.226 140.002 89.257  1.00 170.73 ?  91  TRP A CD1 1 
ATOM   696  C CD2 . TRP A 1 84  ? 117.081 140.502 91.262  1.00 172.12 ?  91  TRP A CD2 1 
ATOM   697  N NE1 . TRP A 1 84  ? 117.234 139.107 89.518  1.00 171.01 ?  91  TRP A NE1 1 
ATOM   698  C CE2 . TRP A 1 84  ? 117.775 139.394 90.743  1.00 170.62 ?  91  TRP A CE2 1 
ATOM   699  C CE3 . TRP A 1 84  ? 117.446 140.998 92.517  1.00 171.58 ?  91  TRP A CE3 1 
ATOM   700  C CZ2 . TRP A 1 84  ? 118.812 138.774 91.434  1.00 169.42 ?  91  TRP A CZ2 1 
ATOM   701  C CZ3 . TRP A 1 84  ? 118.476 140.380 93.201  1.00 168.90 ?  91  TRP A CZ3 1 
ATOM   702  C CH2 . TRP A 1 84  ? 119.149 139.283 92.656  1.00 168.99 ?  91  TRP A CH2 1 
ATOM   703  N N   . ASP A 1 85  ? 111.756 142.671 91.878  1.00 176.30 ?  92  ASP A N   1 
ATOM   704  C CA  . ASP A 1 85  ? 110.798 143.742 92.146  1.00 175.29 ?  92  ASP A CA  1 
ATOM   705  C C   . ASP A 1 85  ? 110.703 143.925 93.659  1.00 173.53 ?  92  ASP A C   1 
ATOM   706  O O   . ASP A 1 85  ? 109.890 143.284 94.328  1.00 172.34 ?  92  ASP A O   1 
ATOM   707  C CB  . ASP A 1 85  ? 109.437 143.419 91.535  1.00 175.66 ?  92  ASP A CB  1 
ATOM   708  C CG  . ASP A 1 85  ? 109.413 143.607 90.033  1.00 175.82 ?  92  ASP A CG  1 
ATOM   709  O OD1 . ASP A 1 85  ? 109.538 144.762 89.577  1.00 173.79 ?  92  ASP A OD1 1 
ATOM   710  O OD2 . ASP A 1 85  ? 109.277 142.601 89.307  1.00 175.10 -1 92  ASP A OD2 1 
ATOM   711  N N   . TRP A 1 86  ? 111.539 144.809 94.193  1.00 165.50 ?  93  TRP A N   1 
ATOM   712  C CA  . TRP A 1 86  ? 111.510 145.118 95.614  1.00 165.20 ?  93  TRP A CA  1 
ATOM   713  C C   . TRP A 1 86  ? 110.396 146.111 95.924  1.00 166.15 ?  93  TRP A C   1 
ATOM   714  O O   . TRP A 1 86  ? 110.059 146.976 95.111  1.00 165.01 ?  93  TRP A O   1 
ATOM   715  C CB  . TRP A 1 86  ? 112.857 145.681 96.064  1.00 163.43 ?  93  TRP A CB  1 
ATOM   716  C CG  . TRP A 1 86  ? 112.971 145.850 97.539  1.00 162.16 ?  93  TRP A CG  1 
ATOM   717  C CD1 . TRP A 1 86  ? 112.820 147.005 98.243  1.00 163.39 ?  93  TRP A CD1 1 
ATOM   718  C CD2 . TRP A 1 86  ? 113.255 144.828 98.499  1.00 163.58 ?  93  TRP A CD2 1 
ATOM   719  N NE1 . TRP A 1 86  ? 112.993 146.767 99.583  1.00 166.34 ?  93  TRP A NE1 1 
ATOM   720  C CE2 . TRP A 1 86  ? 113.264 145.437 99.766  1.00 165.31 ?  93  TRP A CE2 1 
ATOM   721  C CE3 . TRP A 1 86  ? 113.504 143.458 98.409  1.00 162.98 ?  93  TRP A CE3 1 
ATOM   722  C CZ2 . TRP A 1 86  ? 113.514 144.724 100.933 1.00 163.23 ?  93  TRP A CZ2 1 
ATOM   723  C CZ3 . TRP A 1 86  ? 113.749 142.752 99.569  1.00 162.40 ?  93  TRP A CZ3 1 
ATOM   724  C CH2 . TRP A 1 86  ? 113.749 143.385 100.814 1.00 161.99 ?  93  TRP A CH2 1 
ATOM   725  N N   . LYS A 1 87  ? 109.816 145.974 97.117  1.00 169.89 ?  94  LYS A N   1 
ATOM   726  C CA  . LYS A 1 87  ? 108.720 146.846 97.524  1.00 169.66 ?  94  LYS A CA  1 
ATOM   727  C C   . LYS A 1 87  ? 108.818 147.366 98.951  1.00 168.46 ?  94  LYS A C   1 
ATOM   728  O O   . LYS A 1 87  ? 108.039 148.255 99.305  1.00 167.91 ?  94  LYS A O   1 
ATOM   729  C CB  . LYS A 1 87  ? 107.376 146.123 97.356  1.00 168.36 ?  94  LYS A CB  1 
ATOM   730  C CG  . LYS A 1 87  ? 106.973 145.283 98.554  1.00 168.52 ?  94  LYS A CG  1 
ATOM   731  C CD  . LYS A 1 87  ? 105.841 144.338 98.201  1.00 168.22 ?  94  LYS A CD  1 
ATOM   732  C CE  . LYS A 1 87  ? 105.940 143.044 98.986  1.00 168.00 ?  94  LYS A CE  1 
ATOM   733  N NZ  . LYS A 1 87  ? 106.071 143.285 100.449 1.00 166.88 1  94  LYS A NZ  1 
ATOM   734  N N   . PHE A 1 88  ? 109.731 146.857 99.780  1.00 165.31 ?  95  PHE A N   1 
ATOM   735  C CA  . PHE A 1 88  ? 109.780 147.270 101.177 1.00 164.36 ?  95  PHE A CA  1 
ATOM   736  C C   . PHE A 1 88  ? 110.282 148.697 101.355 1.00 165.45 ?  95  PHE A C   1 
ATOM   737  O O   . PHE A 1 88  ? 109.963 149.326 102.368 1.00 166.60 ?  95  PHE A O   1 
ATOM   738  C CB  . PHE A 1 88  ? 110.656 146.309 101.976 1.00 164.84 ?  95  PHE A CB  1 
ATOM   739  C CG  . PHE A 1 88  ? 109.984 145.011 102.313 1.00 166.11 ?  95  PHE A CG  1 
ATOM   740  C CD1 . PHE A 1 88  ? 109.726 144.073 101.329 1.00 166.12 ?  95  PHE A CD1 1 
ATOM   741  C CD2 . PHE A 1 88  ? 109.624 144.723 103.617 1.00 166.39 ?  95  PHE A CD2 1 
ATOM   742  C CE1 . PHE A 1 88  ? 109.110 142.878 101.639 1.00 166.72 ?  95  PHE A CE1 1 
ATOM   743  C CE2 . PHE A 1 88  ? 109.008 143.527 103.933 1.00 167.12 ?  95  PHE A CE2 1 
ATOM   744  C CZ  . PHE A 1 88  ? 108.751 142.604 102.942 1.00 166.48 ?  95  PHE A CZ  1 
ATOM   745  N N   . GLY A 1 89  ? 111.054 149.219 100.415 1.00 163.22 ?  96  GLY A N   1 
ATOM   746  C CA  . GLY A 1 89  ? 111.500 150.593 100.470 1.00 161.93 ?  96  GLY A CA  1 
ATOM   747  C C   . GLY A 1 89  ? 113.002 150.723 100.631 1.00 164.94 ?  96  GLY A C   1 
ATOM   748  O O   . GLY A 1 89  ? 113.778 149.812 100.332 1.00 168.09 ?  96  GLY A O   1 
ATOM   749  N N   . ASP A 1 90  ? 113.413 151.891 101.125 1.00 165.35 ?  97  ASP A N   1 
ATOM   750  C CA  . ASP A 1 90  ? 114.836 152.197 101.232 1.00 165.77 ?  97  ASP A CA  1 
ATOM   751  C C   . ASP A 1 90  ? 115.452 151.576 102.480 1.00 165.08 ?  97  ASP A C   1 
ATOM   752  O O   . ASP A 1 90  ? 116.388 150.775 102.390 1.00 167.49 ?  97  ASP A O   1 
ATOM   753  C CB  . ASP A 1 90  ? 115.048 153.712 101.232 1.00 166.36 ?  97  ASP A CB  1 
ATOM   754  C CG  . ASP A 1 90  ? 116.388 154.110 101.818 1.00 168.99 ?  97  ASP A CG  1 
ATOM   755  O OD1 . ASP A 1 90  ? 117.395 154.068 101.083 1.00 168.69 ?  97  ASP A OD1 1 
ATOM   756  O OD2 . ASP A 1 90  ? 116.436 154.459 103.016 1.00 169.64 -1 97  ASP A OD2 1 
ATOM   757  N N   . ILE A 1 91  ? 114.947 151.953 103.655 1.00 159.72 ?  98  ILE A N   1 
ATOM   758  C CA  . ILE A 1 91  ? 115.518 151.442 104.902 1.00 162.85 ?  98  ILE A CA  1 
ATOM   759  C C   . ILE A 1 91  ? 115.423 149.925 105.003 1.00 163.04 ?  98  ILE A C   1 
ATOM   760  O O   . ILE A 1 91  ? 116.425 149.291 105.373 1.00 163.25 ?  98  ILE A O   1 
ATOM   761  C CB  . ILE A 1 91  ? 114.881 152.161 106.107 1.00 164.44 ?  98  ILE A CB  1 
ATOM   762  C CG1 . ILE A 1 91  ? 115.427 153.584 106.218 1.00 162.56 ?  98  ILE A CG1 1 
ATOM   763  C CG2 . ILE A 1 91  ? 115.144 151.391 107.392 1.00 162.04 ?  98  ILE A CG2 1 
ATOM   764  C CD1 . ILE A 1 91  ? 116.931 153.649 106.355 1.00 158.94 ?  98  ILE A CD1 1 
ATOM   765  N N   . PRO A 1 92  ? 114.286 149.279 104.709 1.00 162.93 ?  99  PRO A N   1 
ATOM   766  C CA  . PRO A 1 92  ? 114.254 147.811 104.829 1.00 164.84 ?  99  PRO A CA  1 
ATOM   767  C C   . PRO A 1 92  ? 115.235 147.100 103.913 1.00 165.05 ?  99  PRO A C   1 
ATOM   768  O O   . PRO A 1 92  ? 115.927 146.179 104.360 1.00 164.52 ?  99  PRO A O   1 
ATOM   769  C CB  . PRO A 1 92  ? 112.801 147.464 104.483 1.00 162.96 ?  99  PRO A CB  1 
ATOM   770  C CG  . PRO A 1 92  ? 112.043 148.700 104.754 1.00 163.17 ?  99  PRO A CG  1 
ATOM   771  C CD  . PRO A 1 92  ? 112.956 149.812 104.364 1.00 161.32 ?  99  PRO A CD  1 
ATOM   772  N N   . CYS A 1 93  ? 115.325 147.506 102.644 1.00 161.61 ?  100 CYS A N   1 
ATOM   773  C CA  . CYS A 1 93  ? 116.225 146.831 101.712 1.00 160.31 ?  100 CYS A CA  1 
ATOM   774  C C   . CYS A 1 93  ? 117.684 147.038 102.099 1.00 161.22 ?  100 CYS A C   1 
ATOM   775  O O   . CYS A 1 93  ? 118.481 146.091 102.093 1.00 163.51 ?  100 CYS A O   1 
ATOM   776  C CB  . CYS A 1 93  ? 115.982 147.335 100.293 1.00 160.42 ?  100 CYS A CB  1 
ATOM   777  S SG  . CYS A 1 93  ? 117.303 146.934 99.143  1.00 165.66 ?  100 CYS A SG  1 
ATOM   778  N N   . ARG A 1 94  ? 118.054 148.276 102.422 1.00 152.30 ?  101 ARG A N   1 
ATOM   779  C CA  . ARG A 1 94  ? 119.425 148.559 102.824 1.00 152.65 ?  101 ARG A CA  1 
ATOM   780  C C   . ARG A 1 94  ? 119.788 147.813 104.101 1.00 151.01 ?  101 ARG A C   1 
ATOM   781  O O   . ARG A 1 94  ? 120.887 147.257 104.219 1.00 150.01 ?  101 ARG A O   1 
ATOM   782  C CB  . ARG A 1 94  ? 119.604 150.063 103.007 1.00 153.19 ?  101 ARG A CB  1 
ATOM   783  C CG  . ARG A 1 94  ? 120.955 150.464 103.531 1.00 152.19 ?  101 ARG A CG  1 
ATOM   784  C CD  . ARG A 1 94  ? 121.384 151.784 102.942 1.00 152.99 ?  101 ARG A CD  1 
ATOM   785  N NE  . ARG A 1 94  ? 120.284 152.736 102.853 1.00 154.95 ?  101 ARG A NE  1 
ATOM   786  C CZ  . ARG A 1 94  ? 120.409 154.042 103.042 1.00 153.88 ?  101 ARG A CZ  1 
ATOM   787  N NH1 . ARG A 1 94  ? 121.577 154.589 103.337 1.00 151.25 1  101 ARG A NH1 1 
ATOM   788  N NH2 . ARG A 1 94  ? 119.335 154.820 102.933 1.00 153.08 ?  101 ARG A NH2 1 
ATOM   789  N N   . LEU A 1 95  ? 118.872 147.792 105.070 1.00 147.54 ?  102 LEU A N   1 
ATOM   790  C CA  . LEU A 1 95  ? 119.118 147.059 106.304 1.00 147.79 ?  102 LEU A CA  1 
ATOM   791  C C   . LEU A 1 95  ? 119.264 145.570 106.036 1.00 149.20 ?  102 LEU A C   1 
ATOM   792  O O   . LEU A 1 95  ? 120.118 144.911 106.633 1.00 152.56 ?  102 LEU A O   1 
ATOM   793  C CB  . LEU A 1 95  ? 117.992 147.317 107.303 1.00 147.80 ?  102 LEU A CB  1 
ATOM   794  C CG  . LEU A 1 95  ? 118.312 146.941 108.749 1.00 148.02 ?  102 LEU A CG  1 
ATOM   795  C CD1 . LEU A 1 95  ? 119.493 147.751 109.262 1.00 145.93 ?  102 LEU A CD1 1 
ATOM   796  C CD2 . LEU A 1 95  ? 117.093 147.138 109.633 1.00 147.09 ?  102 LEU A CD2 1 
ATOM   797  N N   . MET A 1 96  ? 118.436 145.021 105.146 1.00 144.13 ?  103 MET A N   1 
ATOM   798  C CA  . MET A 1 96  ? 118.535 143.603 104.822 1.00 143.73 ?  103 MET A CA  1 
ATOM   799  C C   . MET A 1 96  ? 119.871 143.277 104.169 1.00 147.14 ?  103 MET A C   1 
ATOM   800  O O   . MET A 1 96  ? 120.507 142.275 104.512 1.00 147.81 ?  103 MET A O   1 
ATOM   801  C CB  . MET A 1 96  ? 117.374 143.196 103.918 1.00 142.45 ?  103 MET A CB  1 
ATOM   802  C CG  . MET A 1 96  ? 117.593 141.906 103.162 1.00 143.31 ?  103 MET A CG  1 
ATOM   803  S SD  . MET A 1 96  ? 116.658 141.885 101.628 1.00 148.88 ?  103 MET A SD  1 
ATOM   804  C CE  . MET A 1 96  ? 117.827 141.104 100.527 1.00 143.41 ?  103 MET A CE  1 
ATOM   805  N N   . LEU A 1 97  ? 120.319 144.119 103.234 1.00 138.04 ?  104 LEU A N   1 
ATOM   806  C CA  . LEU A 1 97  ? 121.608 143.893 102.582 1.00 131.30 ?  104 LEU A CA  1 
ATOM   807  C C   . LEU A 1 97  ? 122.753 143.964 103.586 1.00 128.85 ?  104 LEU A C   1 
ATOM   808  O O   . LEU A 1 97  ? 123.644 143.101 103.601 1.00 129.40 ?  104 LEU A O   1 
ATOM   809  C CB  . LEU A 1 97  ? 121.813 144.918 101.469 1.00 127.91 ?  104 LEU A CB  1 
ATOM   810  C CG  . LEU A 1 97  ? 120.897 144.821 100.252 1.00 129.01 ?  104 LEU A CG  1 
ATOM   811  C CD1 . LEU A 1 97  ? 121.553 145.464 99.051  1.00 133.88 ?  104 LEU A CD1 1 
ATOM   812  C CD2 . LEU A 1 97  ? 120.555 143.380 99.956  1.00 129.36 ?  104 LEU A CD2 1 
ATOM   813  N N   . PHE A 1 98  ? 122.744 144.992 104.437 1.00 133.08 ?  105 PHE A N   1 
ATOM   814  C CA  . PHE A 1 98  ? 123.798 145.123 105.435 1.00 134.57 ?  105 PHE A CA  1 
ATOM   815  C C   . PHE A 1 98  ? 123.785 143.953 106.403 1.00 134.17 ?  105 PHE A C   1 
ATOM   816  O O   . PHE A 1 98  ? 124.842 143.431 106.766 1.00 138.20 ?  105 PHE A O   1 
ATOM   817  C CB  . PHE A 1 98  ? 123.655 146.437 106.199 1.00 138.38 ?  105 PHE A CB  1 
ATOM   818  C CG  . PHE A 1 98  ? 124.477 146.493 107.453 1.00 137.38 ?  105 PHE A CG  1 
ATOM   819  C CD1 . PHE A 1 98  ? 125.855 146.462 107.395 1.00 137.43 ?  105 PHE A CD1 1 
ATOM   820  C CD2 . PHE A 1 98  ? 123.870 146.573 108.689 1.00 134.74 ?  105 PHE A CD2 1 
ATOM   821  C CE1 . PHE A 1 98  ? 126.609 146.510 108.548 1.00 137.41 ?  105 PHE A CE1 1 
ATOM   822  C CE2 . PHE A 1 98  ? 124.620 146.619 109.844 1.00 132.06 ?  105 PHE A CE2 1 
ATOM   823  C CZ  . PHE A 1 98  ? 125.989 146.589 109.773 1.00 134.24 ?  105 PHE A CZ  1 
ATOM   824  N N   . MET A 1 99  ? 122.598 143.535 106.843 1.00 132.09 ?  106 MET A N   1 
ATOM   825  C CA  . MET A 1 99  ? 122.508 142.417 107.769 1.00 136.37 ?  106 MET A CA  1 
ATOM   826  C C   . MET A 1 99  ? 123.012 141.134 107.124 1.00 137.57 ?  106 MET A C   1 
ATOM   827  O O   . MET A 1 99  ? 123.756 140.376 107.751 1.00 134.56 ?  106 MET A O   1 
ATOM   828  C CB  . MET A 1 99  ? 121.067 142.251 108.252 1.00 133.27 ?  106 MET A CB  1 
ATOM   829  C CG  . MET A 1 99  ? 120.875 141.931 109.748 1.00 137.39 ?  106 MET A CG  1 
ATOM   830  S SD  . MET A 1 99  ? 121.812 142.763 111.051 1.00 148.30 ?  106 MET A SD  1 
ATOM   831  C CE  . MET A 1 99  ? 121.958 144.432 110.432 1.00 136.41 ?  106 MET A CE  1 
ATOM   832  N N   . LEU A 1 100 ? 122.640 140.885 105.865 1.00 129.18 ?  107 LEU A N   1 
ATOM   833  C CA  . LEU A 1 100 ? 123.127 139.696 105.171 1.00 123.89 ?  107 LEU A CA  1 
ATOM   834  C C   . LEU A 1 100 ? 124.647 139.685 105.110 1.00 125.94 ?  107 LEU A C   1 
ATOM   835  O O   . LEU A 1 100 ? 125.288 138.708 105.516 1.00 128.27 ?  107 LEU A O   1 
ATOM   836  C CB  . LEU A 1 100 ? 122.550 139.625 103.757 1.00 121.82 ?  107 LEU A CB  1 
ATOM   837  C CG  . LEU A 1 100 ? 121.091 139.239 103.532 1.00 124.78 ?  107 LEU A CG  1 
ATOM   838  C CD1 . LEU A 1 100 ? 120.689 139.608 102.124 1.00 125.09 ?  107 LEU A CD1 1 
ATOM   839  C CD2 . LEU A 1 100 ? 120.882 137.760 103.759 1.00 125.86 ?  107 LEU A CD2 1 
ATOM   840  N N   . ALA A 1 101 ? 125.244 140.774 104.618 1.00 127.97 ?  108 ALA A N   1 
ATOM   841  C CA  . ALA A 1 101 ? 126.696 140.805 104.467 1.00 123.25 ?  108 ALA A CA  1 
ATOM   842  C C   . ALA A 1 101 ? 127.396 140.704 105.817 1.00 122.20 ?  108 ALA A C   1 
ATOM   843  O O   . ALA A 1 101 ? 128.312 139.891 105.997 1.00 127.73 ?  108 ALA A O   1 
ATOM   844  C CB  . ALA A 1 101 ? 127.121 142.075 103.735 1.00 121.11 ?  108 ALA A CB  1 
ATOM   845  N N   . MET A 1 102 ? 126.968 141.517 106.785 1.00 122.66 ?  109 MET A N   1 
ATOM   846  C CA  . MET A 1 102 ? 127.624 141.542 108.084 1.00 124.24 ?  109 MET A CA  1 
ATOM   847  C C   . MET A 1 102 ? 127.493 140.205 108.795 1.00 124.61 ?  109 MET A C   1 
ATOM   848  O O   . MET A 1 102 ? 128.446 139.737 109.419 1.00 126.05 ?  109 MET A O   1 
ATOM   849  C CB  . MET A 1 102 ? 127.044 142.666 108.941 1.00 127.16 ?  109 MET A CB  1 
ATOM   850  C CG  . MET A 1 102 ? 127.751 142.863 110.273 1.00 130.10 ?  109 MET A CG  1 
ATOM   851  S SD  . MET A 1 102 ? 127.017 141.951 111.640 1.00 137.83 ?  109 MET A SD  1 
ATOM   852  C CE  . MET A 1 102 ? 125.292 141.988 111.180 1.00 127.04 ?  109 MET A CE  1 
ATOM   853  N N   . ASN A 1 103 ? 126.324 139.568 108.710 1.00 123.21 ?  110 ASN A N   1 
ATOM   854  C CA  . ASN A 1 103 ? 126.120 138.309 109.409 1.00 127.21 ?  110 ASN A CA  1 
ATOM   855  C C   . ASN A 1 103 ? 126.825 137.148 108.725 1.00 127.57 ?  110 ASN A C   1 
ATOM   856  O O   . ASN A 1 103 ? 127.329 136.259 109.414 1.00 127.47 ?  110 ASN A O   1 
ATOM   857  C CB  . ASN A 1 103 ? 124.627 138.025 109.543 1.00 127.69 ?  110 ASN A CB  1 
ATOM   858  C CG  . ASN A 1 103 ? 123.988 138.824 110.656 1.00 128.85 ?  110 ASN A CG  1 
ATOM   859  O OD1 . ASN A 1 103 ? 123.078 139.615 110.424 1.00 127.78 ?  110 ASN A OD1 1 
ATOM   860  N ND2 . ASN A 1 103 ? 124.476 138.632 111.874 1.00 129.48 ?  110 ASN A ND2 1 
ATOM   861  N N   . ARG A 1 104 ? 126.887 137.130 107.392 1.00 113.18 ?  111 ARG A N   1 
ATOM   862  C CA  . ARG A 1 104 ? 127.700 136.121 106.723 1.00 106.95 ?  111 ARG A CA  1 
ATOM   863  C C   . ARG A 1 104 ? 129.165 136.265 107.113 1.00 109.60 ?  111 ARG A C   1 
ATOM   864  O O   . ARG A 1 104 ? 129.834 135.279 107.449 1.00 118.21 ?  111 ARG A O   1 
ATOM   865  C CB  . ARG A 1 104 ? 127.529 136.231 105.210 1.00 104.29 ?  111 ARG A CB  1 
ATOM   866  C CG  . ARG A 1 104 ? 128.519 135.403 104.424 1.00 107.26 ?  111 ARG A CG  1 
ATOM   867  C CD  . ARG A 1 104 ? 128.249 135.496 102.939 1.00 113.66 ?  111 ARG A CD  1 
ATOM   868  N NE  . ARG A 1 104 ? 127.907 136.852 102.532 1.00 114.77 ?  111 ARG A NE  1 
ATOM   869  C CZ  . ARG A 1 104 ? 126.891 137.161 101.739 1.00 112.77 ?  111 ARG A CZ  1 
ATOM   870  N NH1 . ARG A 1 104 ? 126.092 136.230 101.249 1.00 112.48 1  111 ARG A NH1 1 
ATOM   871  N NH2 . ARG A 1 104 ? 126.674 138.435 101.429 1.00 107.94 ?  111 ARG A NH2 1 
ATOM   872  N N   . GLN A 1 105 ? 129.673 137.501 107.105 1.00 110.33 ?  112 GLN A N   1 
ATOM   873  C CA  . GLN A 1 105 ? 131.059 137.734 107.498 1.00 108.06 ?  112 GLN A CA  1 
ATOM   874  C C   . GLN A 1 105 ? 131.293 137.359 108.957 1.00 110.02 ?  112 GLN A C   1 
ATOM   875  O O   . GLN A 1 105 ? 132.335 136.793 109.299 1.00 107.32 ?  112 GLN A O   1 
ATOM   876  C CB  . GLN A 1 105 ? 131.429 139.195 107.246 1.00 110.59 ?  112 GLN A CB  1 
ATOM   877  C CG  . GLN A 1 105 ? 132.738 139.627 107.868 1.00 113.36 ?  112 GLN A CG  1 
ATOM   878  C CD  . GLN A 1 105 ? 133.784 139.981 106.833 1.00 116.66 ?  112 GLN A CD  1 
ATOM   879  O OE1 . GLN A 1 105 ? 133.935 139.292 105.827 1.00 117.23 ?  112 GLN A OE1 1 
ATOM   880  N NE2 . GLN A 1 105 ? 134.515 141.063 107.076 1.00 117.31 ?  112 GLN A NE2 1 
ATOM   881  N N   . GLY A 1 106 ? 130.335 137.666 109.831 1.00 114.65 ?  113 GLY A N   1 
ATOM   882  C CA  . GLY A 1 106 ? 130.481 137.319 111.235 1.00 109.13 ?  113 GLY A CA  1 
ATOM   883  C C   . GLY A 1 106 ? 130.444 135.825 111.479 1.00 112.69 ?  113 GLY A C   1 
ATOM   884  O O   . GLY A 1 106 ? 131.194 135.306 112.307 1.00 118.98 ?  113 GLY A O   1 
ATOM   885  N N   . SER A 1 107 ? 129.569 135.111 110.769 1.00 103.92 ?  114 SER A N   1 
ATOM   886  C CA  . SER A 1 107 ? 129.546 133.659 110.882 1.00 103.79 ?  114 SER A CA  1 
ATOM   887  C C   . SER A 1 107 ? 130.859 133.057 110.402 1.00 107.19 ?  114 SER A C   1 
ATOM   888  O O   . SER A 1 107 ? 131.377 132.120 111.016 1.00 111.33 ?  114 SER A O   1 
ATOM   889  C CB  . SER A 1 107 ? 128.367 133.087 110.099 1.00 102.25 ?  114 SER A CB  1 
ATOM   890  O OG  . SER A 1 107 ? 128.714 132.859 108.748 1.00 104.98 ?  114 SER A OG  1 
ATOM   891  N N   . ILE A 1 108 ? 131.422 133.592 109.316 1.00 93.09  ?  115 ILE A N   1 
ATOM   892  C CA  . ILE A 1 108 ? 132.726 133.119 108.852 1.00 87.29  ?  115 ILE A CA  1 
ATOM   893  C C   . ILE A 1 108 ? 133.807 133.411 109.888 1.00 93.91  ?  115 ILE A C   1 
ATOM   894  O O   . ILE A 1 108 ? 134.675 132.570 110.161 1.00 101.55 ?  115 ILE A O   1 
ATOM   895  C CB  . ILE A 1 108 ? 133.065 133.745 107.490 1.00 85.34  ?  115 ILE A CB  1 
ATOM   896  C CG1 . ILE A 1 108 ? 132.261 133.074 106.381 1.00 85.81  ?  115 ILE A CG1 1 
ATOM   897  C CG2 . ILE A 1 108 ? 134.544 133.630 107.208 1.00 92.19  ?  115 ILE A CG2 1 
ATOM   898  C CD1 . ILE A 1 108 ? 132.552 133.629 105.017 1.00 90.41  ?  115 ILE A CD1 1 
ATOM   899  N N   . ILE A 1 109 ? 133.774 134.606 110.477 1.00 94.97  ?  116 ILE A N   1 
ATOM   900  C CA  . ILE A 1 109 ? 134.781 134.987 111.462 1.00 90.55  ?  116 ILE A CA  1 
ATOM   901  C C   . ILE A 1 109 ? 134.704 134.083 112.683 1.00 91.06  ?  116 ILE A C   1 
ATOM   902  O O   . ILE A 1 109 ? 135.729 133.671 113.234 1.00 95.41  ?  116 ILE A O   1 
ATOM   903  C CB  . ILE A 1 109 ? 134.621 136.471 111.840 1.00 100.54 ?  116 ILE A CB  1 
ATOM   904  C CG1 . ILE A 1 109 ? 135.404 137.351 110.868 1.00 98.68  ?  116 ILE A CG1 1 
ATOM   905  C CG2 . ILE A 1 109 ? 135.078 136.722 113.262 1.00 101.47 ?  116 ILE A CG2 1 
ATOM   906  C CD1 . ILE A 1 109 ? 134.829 138.731 110.703 1.00 97.98  ?  116 ILE A CD1 1 
ATOM   907  N N   . PHE A 1 110 ? 133.492 133.750 113.122 1.00 97.13  ?  117 PHE A N   1 
ATOM   908  C CA  . PHE A 1 110 ? 133.358 132.893 114.293 1.00 93.94  ?  117 PHE A CA  1 
ATOM   909  C C   . PHE A 1 110 ? 133.652 131.434 113.972 1.00 98.92  ?  117 PHE A C   1 
ATOM   910  O O   . PHE A 1 110 ? 134.141 130.707 114.839 1.00 101.70 ?  117 PHE A O   1 
ATOM   911  C CB  . PHE A 1 110 ? 131.972 133.066 114.907 1.00 93.10  ?  117 PHE A CB  1 
ATOM   912  C CG  . PHE A 1 110 ? 131.833 134.334 115.692 1.00 99.62  ?  117 PHE A CG  1 
ATOM   913  C CD1 . PHE A 1 110 ? 132.610 134.550 116.814 1.00 105.26 ?  117 PHE A CD1 1 
ATOM   914  C CD2 . PHE A 1 110 ? 130.961 135.325 115.289 1.00 100.50 ?  117 PHE A CD2 1 
ATOM   915  C CE1 . PHE A 1 110 ? 132.503 135.719 117.530 1.00 106.51 ?  117 PHE A CE1 1 
ATOM   916  C CE2 . PHE A 1 110 ? 130.851 136.496 116.000 1.00 102.43 ?  117 PHE A CE2 1 
ATOM   917  C CZ  . PHE A 1 110 ? 131.622 136.694 117.122 1.00 106.19 ?  117 PHE A CZ  1 
ATOM   918  N N   . LEU A 1 111 ? 133.400 130.999 112.736 1.00 100.32 ?  118 LEU A N   1 
ATOM   919  C CA  . LEU A 1 111 ? 133.911 129.710 112.281 1.00 91.64  ?  118 LEU A CA  1 
ATOM   920  C C   . LEU A 1 111 ? 135.426 129.654 112.411 1.00 96.47  ?  118 LEU A C   1 
ATOM   921  O O   . LEU A 1 111 ? 135.985 128.694 112.955 1.00 103.06 ?  118 LEU A O   1 
ATOM   922  C CB  . LEU A 1 111 ? 133.497 129.481 110.829 1.00 86.74  ?  118 LEU A CB  1 
ATOM   923  C CG  . LEU A 1 111 ? 132.286 128.611 110.531 1.00 96.18  ?  118 LEU A CG  1 
ATOM   924  C CD1 . LEU A 1 111 ? 131.497 129.193 109.378 1.00 95.40  ?  118 LEU A CD1 1 
ATOM   925  C CD2 . LEU A 1 111 ? 132.759 127.223 110.181 1.00 103.33 ?  118 LEU A CD2 1 
ATOM   926  N N   . THR A 1 112 ? 136.108 130.689 111.916 1.00 86.14  ?  119 THR A N   1 
ATOM   927  C CA  . THR A 1 112 ? 137.564 130.733 111.994 1.00 75.92  ?  119 THR A CA  1 
ATOM   928  C C   . THR A 1 112 ? 138.042 130.794 113.439 1.00 82.14  ?  119 THR A C   1 
ATOM   929  O O   . THR A 1 112 ? 139.047 130.171 113.796 1.00 94.03  ?  119 THR A O   1 
ATOM   930  C CB  . THR A 1 112 ? 138.089 131.929 111.206 1.00 80.55  ?  119 THR A CB  1 
ATOM   931  O OG1 . THR A 1 112 ? 137.636 131.837 109.852 1.00 96.72  ?  119 THR A OG1 1 
ATOM   932  C CG2 . THR A 1 112 ? 139.597 131.956 111.219 1.00 84.16  ?  119 THR A CG2 1 
ATOM   933  N N   . VAL A 1 113 ? 137.337 131.543 114.284 1.00 91.12  ?  120 VAL A N   1 
ATOM   934  C CA  . VAL A 1 113 ? 137.726 131.652 115.686 1.00 88.11  ?  120 VAL A CA  1 
ATOM   935  C C   . VAL A 1 113 ? 137.562 130.315 116.395 1.00 91.17  ?  120 VAL A C   1 
ATOM   936  O O   . VAL A 1 113 ? 138.408 129.922 117.204 1.00 96.97  ?  120 VAL A O   1 
ATOM   937  C CB  . VAL A 1 113 ? 136.921 132.770 116.370 1.00 88.10  ?  120 VAL A CB  1 
ATOM   938  C CG1 . VAL A 1 113 ? 136.805 132.519 117.859 1.00 89.00  ?  120 VAL A CG1 1 
ATOM   939  C CG2 . VAL A 1 113 ? 137.579 134.105 116.108 1.00 89.92  ?  120 VAL A CG2 1 
ATOM   940  N N   . VAL A 1 114 ? 136.481 129.592 116.102 1.00 88.15  ?  121 VAL A N   1 
ATOM   941  C CA  . VAL A 1 114 ? 136.286 128.268 116.686 1.00 80.02  ?  121 VAL A CA  1 
ATOM   942  C C   . VAL A 1 114 ? 137.370 127.311 116.207 1.00 86.10  ?  121 VAL A C   1 
ATOM   943  O O   . VAL A 1 114 ? 137.895 126.504 116.985 1.00 96.83  ?  121 VAL A O   1 
ATOM   944  C CB  . VAL A 1 114 ? 134.875 127.749 116.358 1.00 83.13  ?  121 VAL A CB  1 
ATOM   945  C CG1 . VAL A 1 114 ? 134.896 126.262 116.089 1.00 86.86  ?  121 VAL A CG1 1 
ATOM   946  C CG2 . VAL A 1 114 ? 133.922 128.072 117.491 1.00 87.37  ?  121 VAL A CG2 1 
ATOM   947  N N   . ALA A 1 115 ? 137.727 127.387 114.924 1.00 82.54  ?  122 ALA A N   1 
ATOM   948  C CA  . ALA A 1 115 ? 138.788 126.530 114.408 1.00 73.62  ?  122 ALA A CA  1 
ATOM   949  C C   . ALA A 1 115 ? 140.120 126.832 115.083 1.00 79.06  ?  122 ALA A C   1 
ATOM   950  O O   . ALA A 1 115 ? 140.869 125.913 115.429 1.00 93.32  ?  122 ALA A O   1 
ATOM   951  C CB  . ALA A 1 115 ? 138.903 126.691 112.895 1.00 79.82  ?  122 ALA A CB  1 
ATOM   952  N N   . VAL A 1 116 ? 140.430 128.112 115.288 1.00 76.59  ?  123 VAL A N   1 
ATOM   953  C CA  . VAL A 1 116 ? 141.678 128.477 115.952 1.00 77.55  ?  123 VAL A CA  1 
ATOM   954  C C   . VAL A 1 116 ? 141.657 128.042 117.412 1.00 82.84  ?  123 VAL A C   1 
ATOM   955  O O   . VAL A 1 116 ? 142.678 127.614 117.962 1.00 92.02  ?  123 VAL A O   1 
ATOM   956  C CB  . VAL A 1 116 ? 141.933 129.988 115.812 1.00 78.49  ?  123 VAL A CB  1 
ATOM   957  C CG1 . VAL A 1 116 ? 143.093 130.416 116.687 1.00 80.22  ?  123 VAL A CG1 1 
ATOM   958  C CG2 . VAL A 1 116 ? 142.212 130.337 114.368 1.00 81.22  ?  123 VAL A CG2 1 
ATOM   959  N N   . ASP A 1 117 ? 140.498 128.146 118.061 1.00 88.34  ?  124 ASP A N   1 
ATOM   960  C CA  . ASP A 1 117 ? 140.374 127.692 119.441 1.00 79.10  ?  124 ASP A CA  1 
ATOM   961  C C   . ASP A 1 117 ? 140.631 126.195 119.549 1.00 90.78  ?  124 ASP A C   1 
ATOM   962  O O   . ASP A 1 117 ? 141.367 125.746 120.434 1.00 104.15 ?  124 ASP A O   1 
ATOM   963  C CB  . ASP A 1 117 ? 138.987 128.051 119.972 1.00 88.48  ?  124 ASP A CB  1 
ATOM   964  C CG  . ASP A 1 117 ? 138.667 127.371 121.282 1.00 102.05 ?  124 ASP A CG  1 
ATOM   965  O OD1 . ASP A 1 117 ? 139.320 127.693 122.295 1.00 106.05 ?  124 ASP A OD1 1 
ATOM   966  O OD2 . ASP A 1 117 ? 137.750 126.526 121.303 1.00 100.36 -1 124 ASP A OD2 1 
ATOM   967  N N   . ARG A 1 118 ? 140.056 125.410 118.636 1.00 92.20  ?  125 ARG A N   1 
ATOM   968  C CA  . ARG A 1 118 ? 140.313 123.973 118.632 1.00 87.92  ?  125 ARG A CA  1 
ATOM   969  C C   . ARG A 1 118 ? 141.777 123.672 118.335 1.00 86.62  ?  125 ARG A C   1 
ATOM   970  O O   . ARG A 1 118 ? 142.366 122.758 118.927 1.00 100.40 ?  125 ARG A O   1 
ATOM   971  C CB  . ARG A 1 118 ? 139.409 123.282 117.616 1.00 84.37  ?  125 ARG A CB  1 
ATOM   972  C CG  . ARG A 1 118 ? 137.943 123.362 117.963 1.00 89.33  ?  125 ARG A CG  1 
ATOM   973  C CD  . ARG A 1 118 ? 137.076 122.948 116.798 1.00 93.52  ?  125 ARG A CD  1 
ATOM   974  N NE  . ARG A 1 118 ? 135.679 122.827 117.192 1.00 99.96  ?  125 ARG A NE  1 
ATOM   975  C CZ  . ARG A 1 118 ? 134.709 122.421 116.387 1.00 102.05 ?  125 ARG A CZ  1 
ATOM   976  N NH1 . ARG A 1 118 ? 134.950 122.091 115.129 1.00 97.17  1  125 ARG A NH1 1 
ATOM   977  N NH2 . ARG A 1 118 ? 133.468 122.342 116.855 1.00 96.87  ?  125 ARG A NH2 1 
ATOM   978  N N   . TYR A 1 119 ? 142.379 124.426 117.413 1.00 80.49  ?  126 TYR A N   1 
ATOM   979  C CA  . TYR A 1 119 ? 143.788 124.225 117.101 1.00 77.04  ?  126 TYR A CA  1 
ATOM   980  C C   . TYR A 1 119 ? 144.657 124.469 118.322 1.00 83.79  ?  126 TYR A C   1 
ATOM   981  O O   . TYR A 1 119 ? 145.592 123.710 118.591 1.00 96.82  ?  126 TYR A O   1 
ATOM   982  C CB  . TYR A 1 119 ? 144.211 125.144 115.956 1.00 84.50  ?  126 TYR A CB  1 
ATOM   983  C CG  . TYR A 1 119 ? 145.705 125.322 115.835 1.00 81.16  ?  126 TYR A CG  1 
ATOM   984  C CD1 . TYR A 1 119 ? 146.480 124.385 115.176 1.00 85.78  ?  126 TYR A CD1 1 
ATOM   985  C CD2 . TYR A 1 119 ? 146.340 126.427 116.379 1.00 84.46  ?  126 TYR A CD2 1 
ATOM   986  C CE1 . TYR A 1 119 ? 147.840 124.541 115.064 1.00 91.27  ?  126 TYR A CE1 1 
ATOM   987  C CE2 . TYR A 1 119 ? 147.701 126.588 116.274 1.00 85.89  ?  126 TYR A CE2 1 
ATOM   988  C CZ  . TYR A 1 119 ? 148.446 125.643 115.615 1.00 93.63  ?  126 TYR A CZ  1 
ATOM   989  O OH  . TYR A 1 119 ? 149.806 125.801 115.503 1.00 93.23  ?  126 TYR A OH  1 
ATOM   990  N N   . PHE A 1 120 ? 144.369 125.529 119.073 1.00 90.45  ?  127 PHE A N   1 
ATOM   991  C CA  . PHE A 1 120 ? 145.154 125.802 120.267 1.00 90.05  ?  127 PHE A CA  1 
ATOM   992  C C   . PHE A 1 120 ? 144.881 124.781 121.359 1.00 95.27  ?  127 PHE A C   1 
ATOM   993  O O   . PHE A 1 120 ? 145.763 124.499 122.174 1.00 96.55  ?  127 PHE A O   1 
ATOM   994  C CB  . PHE A 1 120 ? 144.874 127.214 120.774 1.00 91.73  ?  127 PHE A CB  1 
ATOM   995  C CG  . PHE A 1 120 ? 145.887 128.219 120.327 1.00 102.48 ?  127 PHE A CG  1 
ATOM   996  C CD1 . PHE A 1 120 ? 147.076 128.373 121.015 1.00 100.25 ?  127 PHE A CD1 1 
ATOM   997  C CD2 . PHE A 1 120 ? 145.659 128.999 119.210 1.00 100.55 ?  127 PHE A CD2 1 
ATOM   998  C CE1 . PHE A 1 120 ? 148.014 129.291 120.601 1.00 98.58  ?  127 PHE A CE1 1 
ATOM   999  C CE2 . PHE A 1 120 ? 146.593 129.917 118.792 1.00 98.30  ?  127 PHE A CE2 1 
ATOM   1000 C CZ  . PHE A 1 120 ? 147.772 130.064 119.489 1.00 96.26  ?  127 PHE A CZ  1 
ATOM   1001 N N   . ARG A 1 121 ? 143.673 124.218 121.397 1.00 92.80  ?  128 ARG A N   1 
ATOM   1002 C CA  . ARG A 1 121 ? 143.368 123.234 122.427 1.00 80.88  ?  128 ARG A CA  1 
ATOM   1003 C C   . ARG A 1 121 ? 144.011 121.885 122.140 1.00 80.22  ?  128 ARG A C   1 
ATOM   1004 O O   . ARG A 1 121 ? 144.292 121.129 123.074 1.00 93.99  ?  128 ARG A O   1 
ATOM   1005 C CB  . ARG A 1 121 ? 141.859 123.086 122.579 1.00 75.11  ?  128 ARG A CB  1 
ATOM   1006 C CG  . ARG A 1 121 ? 141.220 124.274 123.257 1.00 86.05  ?  128 ARG A CG  1 
ATOM   1007 C CD  . ARG A 1 121 ? 139.721 124.120 123.366 1.00 87.96  ?  128 ARG A CD  1 
ATOM   1008 N NE  . ARG A 1 121 ? 139.279 124.146 124.754 1.00 92.38  ?  128 ARG A NE  1 
ATOM   1009 C CZ  . ARG A 1 121 ? 139.273 125.227 125.521 1.00 99.46  ?  128 ARG A CZ  1 
ATOM   1010 N NH1 . ARG A 1 121 ? 139.660 126.404 125.061 1.00 97.69  1  128 ARG A NH1 1 
ATOM   1011 N NH2 . ARG A 1 121 ? 138.863 125.125 126.781 1.00 97.58  ?  128 ARG A NH2 1 
ATOM   1012 N N   . VAL A 1 122 ? 144.246 121.558 120.875 1.00 81.53  ?  129 VAL A N   1 
ATOM   1013 C CA  . VAL A 1 122 ? 144.833 120.269 120.510 1.00 70.93  ?  129 VAL A CA  1 
ATOM   1014 C C   . VAL A 1 122 ? 146.347 120.351 120.369 1.00 76.62  ?  129 VAL A C   1 
ATOM   1015 O O   . VAL A 1 122 ? 147.072 119.527 120.923 1.00 88.92  ?  129 VAL A O   1 
ATOM   1016 C CB  . VAL A 1 122 ? 144.184 119.726 119.219 1.00 78.15  ?  129 VAL A CB  1 
ATOM   1017 C CG1 . VAL A 1 122 ? 144.986 118.560 118.686 1.00 77.30  ?  129 VAL A CG1 1 
ATOM   1018 C CG2 . VAL A 1 122 ? 142.763 119.307 119.488 1.00 77.11  ?  129 VAL A CG2 1 
ATOM   1019 N N   . VAL A 1 123 ? 146.848 121.333 119.627 1.00 84.70  ?  130 VAL A N   1 
ATOM   1020 C CA  . VAL A 1 123 ? 148.269 121.370 119.304 1.00 87.15  ?  130 VAL A CA  1 
ATOM   1021 C C   . VAL A 1 123 ? 149.102 122.038 120.396 1.00 90.02  ?  130 VAL A C   1 
ATOM   1022 O O   . VAL A 1 123 ? 150.287 121.725 120.545 1.00 96.88  ?  130 VAL A O   1 
ATOM   1023 C CB  . VAL A 1 123 ? 148.472 122.060 117.946 1.00 85.54  ?  130 VAL A CB  1 
ATOM   1024 C CG1 . VAL A 1 123 ? 149.904 121.920 117.479 1.00 91.29  ?  130 VAL A CG1 1 
ATOM   1025 C CG2 . VAL A 1 123 ? 147.532 121.462 116.922 1.00 86.33  ?  130 VAL A CG2 1 
ATOM   1026 N N   . HIS A 1 124 ? 148.516 122.941 121.174 1.00 95.38  ?  131 HIS A N   1 
ATOM   1027 C CA  . HIS A 1 124 ? 149.191 123.568 122.310 1.00 98.78  ?  131 HIS A CA  1 
ATOM   1028 C C   . HIS A 1 124 ? 148.308 123.426 123.541 1.00 100.67 ?  131 HIS A C   1 
ATOM   1029 O O   . HIS A 1 124 ? 147.744 124.408 124.036 1.00 100.64 ?  131 HIS A O   1 
ATOM   1030 C CB  . HIS A 1 124 ? 149.505 125.038 122.030 1.00 102.93 ?  131 HIS A CB  1 
ATOM   1031 C CG  . HIS A 1 124 ? 150.139 125.280 120.696 1.00 104.36 ?  131 HIS A CG  1 
ATOM   1032 N ND1 . HIS A 1 124 ? 151.306 124.663 120.303 1.00 100.86 ?  131 HIS A ND1 1 
ATOM   1033 C CD2 . HIS A 1 124 ? 149.771 126.079 119.667 1.00 103.54 ?  131 HIS A CD2 1 
ATOM   1034 C CE1 . HIS A 1 124 ? 151.628 125.068 119.088 1.00 101.13 ?  131 HIS A CE1 1 
ATOM   1035 N NE2 . HIS A 1 124 ? 150.712 125.927 118.679 1.00 105.40 ?  131 HIS A NE2 1 
ATOM   1036 N N   . PRO A 1 125 ? 148.169 122.204 124.064 1.00 89.20  ?  132 PRO A N   1 
ATOM   1037 C CA  . PRO A 1 125 ? 147.222 121.993 125.171 1.00 84.80  ?  132 PRO A CA  1 
ATOM   1038 C C   . PRO A 1 125 ? 147.544 122.801 126.413 1.00 95.97  ?  132 PRO A C   1 
ATOM   1039 O O   . PRO A 1 125 ? 146.623 123.240 127.111 1.00 102.75 ?  132 PRO A O   1 
ATOM   1040 C CB  . PRO A 1 125 ? 147.323 120.485 125.424 1.00 86.29  ?  132 PRO A CB  1 
ATOM   1041 C CG  . PRO A 1 125 ? 148.638 120.092 124.876 1.00 87.84  ?  132 PRO A CG  1 
ATOM   1042 C CD  . PRO A 1 125 ? 148.883 120.971 123.704 1.00 83.13  ?  132 PRO A CD  1 
ATOM   1043 N N   . HIS A 1 126 ? 148.823 123.011 126.714 1.00 101.99 ?  133 HIS A N   1 
ATOM   1044 C CA  . HIS A 1 126 ? 149.233 123.834 127.850 1.00 98.97  ?  133 HIS A CA  1 
ATOM   1045 C C   . HIS A 1 126 ? 149.547 125.225 127.313 1.00 107.51 ?  133 HIS A C   1 
ATOM   1046 O O   . HIS A 1 126 ? 150.700 125.570 127.058 1.00 113.45 ?  133 HIS A O   1 
ATOM   1047 C CB  . HIS A 1 126 ? 150.428 123.231 128.578 1.00 97.02  ?  133 HIS A CB  1 
ATOM   1048 C CG  . HIS A 1 126 ? 150.484 121.737 128.525 1.00 102.13 ?  133 HIS A CG  1 
ATOM   1049 N ND1 . HIS A 1 126 ? 149.721 120.934 129.344 1.00 97.56  ?  133 HIS A ND1 1 
ATOM   1050 C CD2 . HIS A 1 126 ? 151.229 120.901 127.766 1.00 103.48 ?  133 HIS A CD2 1 
ATOM   1051 C CE1 . HIS A 1 126 ? 149.984 119.667 129.082 1.00 97.51  ?  133 HIS A CE1 1 
ATOM   1052 N NE2 . HIS A 1 126 ? 150.896 119.619 128.129 1.00 100.73 ?  133 HIS A NE2 1 
ATOM   1053 N N   . HIS A 1 127 ? 148.502 126.027 127.135 1.00 116.86 ?  134 HIS A N   1 
ATOM   1054 C CA  . HIS A 1 127 ? 148.653 127.387 126.648 1.00 112.55 ?  134 HIS A CA  1 
ATOM   1055 C C   . HIS A 1 127 ? 147.637 128.265 127.358 1.00 117.71 ?  134 HIS A C   1 
ATOM   1056 O O   . HIS A 1 127 ? 146.540 127.816 127.699 1.00 119.11 ?  134 HIS A O   1 
ATOM   1057 C CB  . HIS A 1 127 ? 148.466 127.464 125.129 1.00 114.29 ?  134 HIS A CB  1 
ATOM   1058 C CG  . HIS A 1 127 ? 149.013 128.714 124.513 1.00 121.37 ?  134 HIS A CG  1 
ATOM   1059 N ND1 . HIS A 1 127 ? 148.380 129.934 124.616 1.00 119.12 ?  134 HIS A ND1 1 
ATOM   1060 C CD2 . HIS A 1 127 ? 150.132 128.932 123.784 1.00 119.41 ?  134 HIS A CD2 1 
ATOM   1061 C CE1 . HIS A 1 127 ? 149.086 130.850 123.978 1.00 118.18 ?  134 HIS A CE1 1 
ATOM   1062 N NE2 . HIS A 1 127 ? 150.155 130.268 123.464 1.00 118.41 ?  134 HIS A NE2 1 
ATOM   1063 N N   . ALA A 1 128 ? 148.017 129.524 127.584 1.00 123.43 ?  135 ALA A N   1 
ATOM   1064 C CA  . ALA A 1 128 ? 147.130 130.443 128.288 1.00 122.83 ?  135 ALA A CA  1 
ATOM   1065 C C   . ALA A 1 128 ? 145.847 130.690 127.509 1.00 122.26 ?  135 ALA A C   1 
ATOM   1066 O O   . ALA A 1 128 ? 144.811 131.001 128.106 1.00 123.34 ?  135 ALA A O   1 
ATOM   1067 C CB  . ALA A 1 128 ? 147.851 131.762 128.559 1.00 122.18 ?  135 ALA A CB  1 
ATOM   1068 N N   . LEU A 1 129 ? 145.895 130.553 126.183 1.00 106.16 ?  136 LEU A N   1 
ATOM   1069 C CA  . LEU A 1 129 ? 144.712 130.798 125.366 1.00 107.12 ?  136 LEU A CA  1 
ATOM   1070 C C   . LEU A 1 129 ? 143.618 129.777 125.646 1.00 109.98 ?  136 LEU A C   1 
ATOM   1071 O O   . LEU A 1 129 ? 142.430 130.086 125.505 1.00 108.33 ?  136 LEU A O   1 
ATOM   1072 C CB  . LEU A 1 129 ? 145.098 130.789 123.887 1.00 109.56 ?  136 LEU A CB  1 
ATOM   1073 C CG  . LEU A 1 129 ? 144.385 131.750 122.933 1.00 113.81 ?  136 LEU A CG  1 
ATOM   1074 C CD1 . LEU A 1 129 ? 145.173 131.874 121.642 1.00 108.67 ?  136 LEU A CD1 1 
ATOM   1075 C CD2 . LEU A 1 129 ? 142.962 131.306 122.638 1.00 112.20 ?  136 LEU A CD2 1 
ATOM   1076 N N   . ASN A 1 130 ? 143.992 128.563 126.049 1.00 117.70 ?  137 ASN A N   1 
ATOM   1077 C CA  . ASN A 1 130 ? 143.013 127.523 126.334 1.00 114.94 ?  137 ASN A CA  1 
ATOM   1078 C C   . ASN A 1 130 ? 142.268 127.749 127.640 1.00 112.47 ?  137 ASN A C   1 
ATOM   1079 O O   . ASN A 1 130 ? 141.269 127.067 127.889 1.00 109.11 ?  137 ASN A O   1 
ATOM   1080 C CB  . ASN A 1 130 ? 143.693 126.155 126.368 1.00 105.79 ?  137 ASN A CB  1 
ATOM   1081 C CG  . ASN A 1 130 ? 144.486 125.874 125.118 1.00 109.57 ?  137 ASN A CG  1 
ATOM   1082 O OD1 . ASN A 1 130 ? 143.996 126.062 124.009 1.00 117.45 ?  137 ASN A OD1 1 
ATOM   1083 N ND2 . ASN A 1 130 ? 145.719 125.422 125.286 1.00 108.49 ?  137 ASN A ND2 1 
ATOM   1084 N N   . LYS A 1 131 ? 142.722 128.683 128.473 1.00 125.73 ?  138 LYS A N   1 
ATOM   1085 C CA  . LYS A 1 131 ? 142.103 128.944 129.765 1.00 125.96 ?  138 LYS A CA  1 
ATOM   1086 C C   . LYS A 1 131 ? 141.745 130.417 129.916 1.00 126.79 ?  138 LYS A C   1 
ATOM   1087 O O   . LYS A 1 131 ? 141.837 130.974 131.013 1.00 129.35 ?  138 LYS A O   1 
ATOM   1088 C CB  . LYS A 1 131 ? 143.017 128.495 130.905 1.00 125.64 ?  138 LYS A CB  1 
ATOM   1089 C CG  . LYS A 1 131 ? 142.791 127.060 131.350 1.00 124.37 ?  138 LYS A CG  1 
ATOM   1090 C CD  . LYS A 1 131 ? 143.960 126.547 132.169 1.00 124.90 ?  138 LYS A CD  1 
ATOM   1091 C CE  . LYS A 1 131 ? 145.204 126.391 131.314 1.00 126.32 ?  138 LYS A CE  1 
ATOM   1092 N NZ  . LYS A 1 131 ? 145.143 125.176 130.454 1.00 124.68 1  138 LYS A NZ  1 
ATOM   1093 N N   . ILE A 1 132 ? 141.339 131.066 128.822 1.00 126.83 ?  139 ILE A N   1 
ATOM   1094 C CA  . ILE A 1 132 ? 140.929 132.458 128.910 1.00 127.35 ?  139 ILE A CA  1 
ATOM   1095 C C   . ILE A 1 132 ? 139.627 132.556 129.695 1.00 130.86 ?  139 ILE A C   1 
ATOM   1096 O O   . ILE A 1 132 ? 138.784 131.651 129.669 1.00 127.82 ?  139 ILE A O   1 
ATOM   1097 C CB  . ILE A 1 132 ? 140.779 133.092 127.516 1.00 126.20 ?  139 ILE A CB  1 
ATOM   1098 C CG1 . ILE A 1 132 ? 139.708 132.362 126.706 1.00 129.54 ?  139 ILE A CG1 1 
ATOM   1099 C CG2 . ILE A 1 132 ? 142.107 133.099 126.785 1.00 123.10 ?  139 ILE A CG2 1 
ATOM   1100 C CD1 . ILE A 1 132 ? 139.303 133.080 125.443 1.00 127.29 ?  139 ILE A CD1 1 
ATOM   1101 N N   . SER A 1 133 ? 139.468 133.665 130.409 1.00 140.16 ?  140 SER A N   1 
ATOM   1102 C CA  . SER A 1 133 ? 138.285 133.874 131.225 1.00 138.89 ?  140 SER A CA  1 
ATOM   1103 C C   . SER A 1 133 ? 137.063 134.128 130.349 1.00 139.90 ?  140 SER A C   1 
ATOM   1104 O O   . SER A 1 133 ? 137.168 134.478 129.170 1.00 142.13 ?  140 SER A O   1 
ATOM   1105 C CB  . SER A 1 133 ? 138.496 135.049 132.178 1.00 137.35 ?  140 SER A CB  1 
ATOM   1106 O OG  . SER A 1 133 ? 137.986 136.246 131.620 1.00 137.32 ?  140 SER A OG  1 
ATOM   1107 N N   . ASN A 1 134 ? 135.884 133.941 130.947 1.00 137.70 ?  141 ASN A N   1 
ATOM   1108 C CA  . ASN A 1 134 ? 134.642 134.230 130.238 1.00 138.94 ?  141 ASN A CA  1 
ATOM   1109 C C   . ASN A 1 134 ? 134.570 135.698 129.842 1.00 139.52 ?  141 ASN A C   1 
ATOM   1110 O O   . ASN A 1 134 ? 134.051 136.039 128.772 1.00 136.67 ?  141 ASN A O   1 
ATOM   1111 C CB  . ASN A 1 134 ? 133.443 133.850 131.104 1.00 138.56 ?  141 ASN A CB  1 
ATOM   1112 C CG  . ASN A 1 134 ? 132.986 132.429 130.871 1.00 139.56 ?  141 ASN A CG  1 
ATOM   1113 O OD1 . ASN A 1 134 ? 133.737 131.481 131.093 1.00 140.38 ?  141 ASN A OD1 1 
ATOM   1114 N ND2 . ASN A 1 134 ? 131.748 132.271 130.422 1.00 138.21 ?  141 ASN A ND2 1 
ATOM   1115 N N   . ARG A 1 135 ? 135.088 136.583 130.697 1.00 142.38 ?  142 ARG A N   1 
ATOM   1116 C CA  . ARG A 1 135 ? 135.131 138.000 130.360 1.00 142.48 ?  142 ARG A CA  1 
ATOM   1117 C C   . ARG A 1 135 ? 136.007 138.247 129.140 1.00 142.16 ?  142 ARG A C   1 
ATOM   1118 O O   . ARG A 1 135 ? 135.654 139.047 128.267 1.00 140.59 ?  142 ARG A O   1 
ATOM   1119 C CB  . ARG A 1 135 ? 135.633 138.808 131.556 1.00 141.84 ?  142 ARG A CB  1 
ATOM   1120 C CG  . ARG A 1 135 ? 135.130 140.242 131.594 1.00 141.03 ?  142 ARG A CG  1 
ATOM   1121 C CD  . ARG A 1 135 ? 135.614 140.959 132.843 1.00 141.52 ?  142 ARG A CD  1 
ATOM   1122 N NE  . ARG A 1 135 ? 134.994 140.422 134.048 1.00 143.44 ?  142 ARG A NE  1 
ATOM   1123 C CZ  . ARG A 1 135 ? 135.643 140.166 135.175 1.00 140.80 ?  142 ARG A CZ  1 
ATOM   1124 N NH1 . ARG A 1 135 ? 136.942 140.386 135.290 1.00 138.84 1  142 ARG A NH1 1 
ATOM   1125 N NH2 . ARG A 1 135 ? 134.971 139.675 136.213 1.00 140.71 ?  142 ARG A NH2 1 
ATOM   1126 N N   . THR A 1 136 ? 137.153 137.567 129.061 1.00 139.56 ?  143 THR A N   1 
ATOM   1127 C CA  . THR A 1 136 ? 138.015 137.713 127.893 1.00 138.69 ?  143 THR A CA  1 
ATOM   1128 C C   . THR A 1 136 ? 137.308 137.237 126.631 1.00 138.47 ?  143 THR A C   1 
ATOM   1129 O O   . THR A 1 136 ? 137.419 137.867 125.573 1.00 137.16 ?  143 THR A O   1 
ATOM   1130 C CB  . THR A 1 136 ? 139.318 136.944 128.097 1.00 138.14 ?  143 THR A CB  1 
ATOM   1131 O OG1 . THR A 1 136 ? 139.690 136.988 129.480 1.00 139.27 ?  143 THR A OG1 1 
ATOM   1132 C CG2 . THR A 1 136 ? 140.430 137.560 127.263 1.00 135.96 ?  143 THR A CG2 1 
ATOM   1133 N N   . ALA A 1 137 ? 136.571 136.128 126.725 1.00 137.25 ?  144 ALA A N   1 
ATOM   1134 C CA  . ALA A 1 137 ? 135.796 135.655 125.584 1.00 137.70 ?  144 ALA A CA  1 
ATOM   1135 C C   . ALA A 1 137 ? 134.748 136.678 125.170 1.00 140.40 ?  144 ALA A C   1 
ATOM   1136 O O   . ALA A 1 137 ? 134.520 136.894 123.975 1.00 136.57 ?  144 ALA A O   1 
ATOM   1137 C CB  . ALA A 1 137 ? 135.137 134.317 125.913 1.00 132.96 ?  144 ALA A CB  1 
ATOM   1138 N N   . ALA A 1 138 ? 134.095 137.313 126.146 1.00 144.28 ?  145 ALA A N   1 
ATOM   1139 C CA  . ALA A 1 138 ? 133.110 138.342 125.827 1.00 138.48 ?  145 ALA A CA  1 
ATOM   1140 C C   . ALA A 1 138 ? 133.754 139.526 125.114 1.00 137.51 ?  145 ALA A C   1 
ATOM   1141 O O   . ALA A 1 138 ? 133.205 140.040 124.131 1.00 135.78 ?  145 ALA A O   1 
ATOM   1142 C CB  . ALA A 1 138 ? 132.399 138.800 127.099 1.00 133.52 ?  145 ALA A CB  1 
ATOM   1143 N N   . ILE A 1 139 ? 134.921 139.970 125.591 1.00 138.15 ?  146 ILE A N   1 
ATOM   1144 C CA  . ILE A 1 139 ? 135.615 141.073 124.926 1.00 137.96 ?  146 ILE A CA  1 
ATOM   1145 C C   . ILE A 1 139 ? 135.999 140.690 123.503 1.00 138.49 ?  146 ILE A C   1 
ATOM   1146 O O   . ILE A 1 139 ? 135.844 141.489 122.572 1.00 135.55 ?  146 ILE A O   1 
ATOM   1147 C CB  . ILE A 1 139 ? 136.848 141.527 125.732 1.00 140.42 ?  146 ILE A CB  1 
ATOM   1148 C CG1 . ILE A 1 139 ? 136.514 141.687 127.214 1.00 140.11 ?  146 ILE A CG1 1 
ATOM   1149 C CG2 . ILE A 1 139 ? 137.417 142.816 125.160 1.00 136.59 ?  146 ILE A CG2 1 
ATOM   1150 C CD1 . ILE A 1 139 ? 137.724 141.953 128.081 1.00 137.68 ?  146 ILE A CD1 1 
ATOM   1151 N N   . ILE A 1 140 ? 136.514 139.473 123.310 1.00 140.01 ?  147 ILE A N   1 
ATOM   1152 C CA  . ILE A 1 140 ? 136.907 139.049 121.968 1.00 140.58 ?  147 ILE A CA  1 
ATOM   1153 C C   . ILE A 1 140 ? 135.696 138.991 121.046 1.00 139.97 ?  147 ILE A C   1 
ATOM   1154 O O   . ILE A 1 140 ? 135.760 139.421 119.888 1.00 139.15 ?  147 ILE A O   1 
ATOM   1155 C CB  . ILE A 1 140 ? 137.649 137.700 122.017 1.00 139.47 ?  147 ILE A CB  1 
ATOM   1156 C CG1 . ILE A 1 140 ? 138.887 137.805 122.909 1.00 139.91 ?  147 ILE A CG1 1 
ATOM   1157 C CG2 . ILE A 1 140 ? 138.030 137.254 120.614 1.00 137.87 ?  147 ILE A CG2 1 
ATOM   1158 C CD1 . ILE A 1 140 ? 139.979 136.810 122.581 1.00 138.56 ?  147 ILE A CD1 1 
ATOM   1159 N N   . SER A 1 141 ? 134.576 138.455 121.537 1.00 132.25 ?  148 SER A N   1 
ATOM   1160 C CA  . SER A 1 141 ? 133.376 138.374 120.711 1.00 132.84 ?  148 SER A CA  1 
ATOM   1161 C C   . SER A 1 141 ? 132.869 139.761 120.335 1.00 133.36 ?  148 SER A C   1 
ATOM   1162 O O   . SER A 1 141 ? 132.504 140.006 119.176 1.00 129.34 ?  148 SER A O   1 
ATOM   1163 C CB  . SER A 1 141 ? 132.291 137.588 121.444 1.00 130.69 ?  148 SER A CB  1 
ATOM   1164 O OG  . SER A 1 141 ? 132.818 136.403 122.010 1.00 132.36 ?  148 SER A OG  1 
ATOM   1165 N N   . CYS A 1 142 ? 132.845 140.684 121.300 1.00 143.15 ?  149 CYS A N   1 
ATOM   1166 C CA  . CYS A 1 142 ? 132.412 142.045 121.003 1.00 140.28 ?  149 CYS A CA  1 
ATOM   1167 C C   . CYS A 1 142 ? 133.347 142.715 120.006 1.00 138.96 ?  149 CYS A C   1 
ATOM   1168 O O   . CYS A 1 142 ? 132.896 143.432 119.110 1.00 138.78 ?  149 CYS A O   1 
ATOM   1169 C CB  . CYS A 1 142 ? 132.319 142.864 122.290 1.00 138.65 ?  149 CYS A CB  1 
ATOM   1170 S SG  . CYS A 1 142 ? 131.094 142.260 123.471 1.00 147.68 ?  149 CYS A SG  1 
ATOM   1171 N N   . LEU A 1 143 ? 134.654 142.480 120.135 1.00 133.01 ?  150 LEU A N   1 
ATOM   1172 C CA  . LEU A 1 143 ? 135.610 143.110 119.233 1.00 133.83 ?  150 LEU A CA  1 
ATOM   1173 C C   . LEU A 1 143 ? 135.479 142.542 117.820 1.00 136.89 ?  150 LEU A C   1 
ATOM   1174 O O   . LEU A 1 143 ? 135.609 143.276 116.834 1.00 136.78 ?  150 LEU A O   1 
ATOM   1175 C CB  . LEU A 1 143 ? 137.023 142.927 119.796 1.00 134.54 ?  150 LEU A CB  1 
ATOM   1176 C CG  . LEU A 1 143 ? 138.259 143.740 119.377 1.00 135.35 ?  150 LEU A CG  1 
ATOM   1177 C CD1 . LEU A 1 143 ? 139.494 143.187 120.076 1.00 133.92 ?  150 LEU A CD1 1 
ATOM   1178 C CD2 . LEU A 1 143 ? 138.498 143.814 117.886 1.00 132.54 ?  150 LEU A CD2 1 
ATOM   1179 N N   . LEU A 1 144 ? 135.201 141.240 117.700 1.00 129.12 ?  151 LEU A N   1 
ATOM   1180 C CA  . LEU A 1 144 ? 134.982 140.642 116.383 1.00 127.37 ?  151 LEU A CA  1 
ATOM   1181 C C   . LEU A 1 144 ? 133.707 141.170 115.735 1.00 125.91 ?  151 LEU A C   1 
ATOM   1182 O O   . LEU A 1 144 ? 133.685 141.458 114.527 1.00 122.25 ?  151 LEU A O   1 
ATOM   1183 C CB  . LEU A 1 144 ? 134.922 139.122 116.504 1.00 125.77 ?  151 LEU A CB  1 
ATOM   1184 C CG  . LEU A 1 144 ? 136.210 138.409 116.901 1.00 124.05 ?  151 LEU A CG  1 
ATOM   1185 C CD1 . LEU A 1 144 ? 135.890 136.993 117.320 1.00 124.78 ?  151 LEU A CD1 1 
ATOM   1186 C CD2 . LEU A 1 144 ? 137.209 138.424 115.759 1.00 121.85 ?  151 LEU A CD2 1 
ATOM   1187 N N   . TRP A 1 145 ? 132.628 141.278 116.516 1.00 123.29 ?  152 TRP A N   1 
ATOM   1188 C CA  . TRP A 1 145 ? 131.412 141.899 116.002 1.00 121.93 ?  152 TRP A CA  1 
ATOM   1189 C C   . TRP A 1 145 ? 131.686 143.332 115.573 1.00 125.42 ?  152 TRP A C   1 
ATOM   1190 O O   . TRP A 1 145 ? 131.173 143.797 114.546 1.00 125.82 ?  152 TRP A O   1 
ATOM   1191 C CB  . TRP A 1 145 ? 130.309 141.856 117.057 1.00 119.33 ?  152 TRP A CB  1 
ATOM   1192 C CG  . TRP A 1 145 ? 129.577 140.555 117.127 1.00 120.12 ?  152 TRP A CG  1 
ATOM   1193 C CD1 . TRP A 1 145 ? 129.651 139.630 118.122 1.00 119.63 ?  152 TRP A CD1 1 
ATOM   1194 C CD2 . TRP A 1 145 ? 128.650 140.037 116.166 1.00 120.80 ?  152 TRP A CD2 1 
ATOM   1195 N NE1 . TRP A 1 145 ? 128.831 138.567 117.843 1.00 121.03 ?  152 TRP A NE1 1 
ATOM   1196 C CE2 . TRP A 1 145 ? 128.205 138.792 116.646 1.00 120.81 ?  152 TRP A CE2 1 
ATOM   1197 C CE3 . TRP A 1 145 ? 128.156 140.504 114.947 1.00 119.67 ?  152 TRP A CE3 1 
ATOM   1198 C CZ2 . TRP A 1 145 ? 127.291 138.010 115.950 1.00 117.44 ?  152 TRP A CZ2 1 
ATOM   1199 C CZ3 . TRP A 1 145 ? 127.249 139.724 114.259 1.00 119.87 ?  152 TRP A CZ3 1 
ATOM   1200 C CH2 . TRP A 1 145 ? 126.827 138.492 114.761 1.00 117.26 ?  152 TRP A CH2 1 
ATOM   1201 N N   . GLY A 1 146 ? 132.508 144.042 116.345 1.00 126.76 ?  153 GLY A N   1 
ATOM   1202 C CA  . GLY A 1 146 ? 132.901 145.382 115.959 1.00 124.63 ?  153 GLY A CA  1 
ATOM   1203 C C   . GLY A 1 146 ? 133.639 145.408 114.638 1.00 125.30 ?  153 GLY A C   1 
ATOM   1204 O O   . GLY A 1 146 ? 133.397 146.279 113.807 1.00 128.58 ?  153 GLY A O   1 
ATOM   1205 N N   . ILE A 1 147 ? 134.535 144.445 114.419 1.00 125.92 ?  154 ILE A N   1 
ATOM   1206 C CA  . ILE A 1 147 ? 135.278 144.403 113.160 1.00 130.14 ?  154 ILE A CA  1 
ATOM   1207 C C   . ILE A 1 147 ? 134.325 144.203 111.988 1.00 131.04 ?  154 ILE A C   1 
ATOM   1208 O O   . ILE A 1 147 ? 134.358 144.951 110.999 1.00 131.01 ?  154 ILE A O   1 
ATOM   1209 C CB  . ILE A 1 147 ? 136.345 143.293 113.190 1.00 128.24 ?  154 ILE A CB  1 
ATOM   1210 C CG1 . ILE A 1 147 ? 137.492 143.643 114.134 1.00 128.21 ?  154 ILE A CG1 1 
ATOM   1211 C CG2 . ILE A 1 147 ? 136.887 143.036 111.795 1.00 125.30 ?  154 ILE A CG2 1 
ATOM   1212 C CD1 . ILE A 1 147 ? 138.142 142.422 114.730 1.00 125.75 ?  154 ILE A CD1 1 
ATOM   1213 N N   . THR A 1 148 ? 133.465 143.184 112.078 1.00 132.02 ?  155 THR A N   1 
ATOM   1214 C CA  . THR A 1 148 ? 132.605 142.877 110.937 1.00 131.38 ?  155 THR A CA  1 
ATOM   1215 C C   . THR A 1 148 ? 131.639 144.023 110.660 1.00 132.14 ?  155 THR A C   1 
ATOM   1216 O O   . THR A 1 148 ? 131.430 144.403 109.500 1.00 130.90 ?  155 THR A O   1 
ATOM   1217 C CB  . THR A 1 148 ? 131.855 141.556 111.147 1.00 131.16 ?  155 THR A CB  1 
ATOM   1218 O OG1 . THR A 1 148 ? 130.893 141.382 110.100 1.00 129.98 ?  155 THR A OG1 1 
ATOM   1219 C CG2 . THR A 1 148 ? 131.142 141.520 112.476 1.00 126.42 ?  155 THR A CG2 1 
ATOM   1220 N N   . ILE A 1 149 ? 131.079 144.623 111.713 1.00 134.71 ?  156 ILE A N   1 
ATOM   1221 C CA  . ILE A 1 149 ? 130.232 145.798 111.530 1.00 133.22 ?  156 ILE A CA  1 
ATOM   1222 C C   . ILE A 1 149 ? 131.038 146.931 110.903 1.00 132.07 ?  156 ILE A C   1 
ATOM   1223 O O   . ILE A 1 149 ? 130.574 147.618 109.986 1.00 133.13 ?  156 ILE A O   1 
ATOM   1224 C CB  . ILE A 1 149 ? 129.602 146.215 112.871 1.00 131.67 ?  156 ILE A CB  1 
ATOM   1225 C CG1 . ILE A 1 149 ? 128.513 145.219 113.271 1.00 129.52 ?  156 ILE A CG1 1 
ATOM   1226 C CG2 . ILE A 1 149 ? 129.035 147.613 112.792 1.00 133.48 ?  156 ILE A CG2 1 
ATOM   1227 C CD1 . ILE A 1 149 ? 128.135 145.279 114.729 1.00 128.32 ?  156 ILE A CD1 1 
ATOM   1228 N N   . GLY A 1 150 ? 132.270 147.120 111.364 1.00 128.43 ?  157 GLY A N   1 
ATOM   1229 C CA  . GLY A 1 150 ? 133.114 148.191 110.886 1.00 130.14 ?  157 GLY A CA  1 
ATOM   1230 C C   . GLY A 1 150 ? 133.372 148.152 109.399 1.00 132.88 ?  157 GLY A C   1 
ATOM   1231 O O   . GLY A 1 150 ? 133.261 149.186 108.735 1.00 136.33 ?  157 GLY A O   1 
ATOM   1232 N N   . LEU A 1 151 ? 133.708 146.988 108.847 1.00 134.10 ?  158 LEU A N   1 
ATOM   1233 C CA  . LEU A 1 151 ? 133.879 146.940 107.397 1.00 135.50 ?  158 LEU A CA  1 
ATOM   1234 C C   . LEU A 1 151 ? 132.661 146.391 106.661 1.00 137.90 ?  158 LEU A C   1 
ATOM   1235 O O   . LEU A 1 151 ? 132.793 145.978 105.506 1.00 136.04 ?  158 LEU A O   1 
ATOM   1236 C CB  . LEU A 1 151 ? 135.131 146.161 106.963 1.00 135.63 ?  158 LEU A CB  1 
ATOM   1237 C CG  . LEU A 1 151 ? 135.564 144.717 107.215 1.00 136.77 ?  158 LEU A CG  1 
ATOM   1238 C CD1 . LEU A 1 151 ? 136.788 144.441 106.369 1.00 135.83 ?  158 LEU A CD1 1 
ATOM   1239 C CD2 . LEU A 1 151 ? 135.946 144.506 108.634 1.00 133.63 ?  158 LEU A CD2 1 
ATOM   1240 N N   . THR A 1 152 ? 131.481 146.377 107.287 1.00 137.93 ?  159 THR A N   1 
ATOM   1241 C CA  . THR A 1 152 ? 130.262 146.127 106.528 1.00 134.38 ?  159 THR A CA  1 
ATOM   1242 C C   . THR A 1 152 ? 129.264 147.283 106.521 1.00 136.80 ?  159 THR A C   1 
ATOM   1243 O O   . THR A 1 152 ? 128.342 147.263 105.699 1.00 136.31 ?  159 THR A O   1 
ATOM   1244 C CB  . THR A 1 152 ? 129.558 144.866 107.047 1.00 135.79 ?  159 THR A CB  1 
ATOM   1245 O OG1 . THR A 1 152 ? 129.593 144.847 108.478 1.00 136.63 ?  159 THR A OG1 1 
ATOM   1246 C CG2 . THR A 1 152 ? 130.242 143.624 106.509 1.00 135.14 ?  159 THR A CG2 1 
ATOM   1247 N N   . VAL A 1 153 ? 129.411 148.286 107.391 1.00 139.66 ?  160 VAL A N   1 
ATOM   1248 C CA  . VAL A 1 153 ? 128.448 149.387 107.427 1.00 140.16 ?  160 VAL A CA  1 
ATOM   1249 C C   . VAL A 1 153 ? 128.433 150.240 106.167 1.00 137.29 ?  160 VAL A C   1 
ATOM   1250 O O   . VAL A 1 153 ? 127.541 151.079 106.022 1.00 134.95 ?  160 VAL A O   1 
ATOM   1251 C CB  . VAL A 1 153 ? 128.672 150.318 108.639 1.00 137.40 ?  160 VAL A CB  1 
ATOM   1252 C CG1 . VAL A 1 153 ? 128.350 149.610 109.930 1.00 136.56 ?  160 VAL A CG1 1 
ATOM   1253 C CG2 . VAL A 1 153 ? 130.102 150.833 108.650 1.00 134.38 ?  160 VAL A CG2 1 
ATOM   1254 N N   . HIS A 1 154 ? 129.395 150.067 105.257 1.00 142.47 ?  161 HIS A N   1 
ATOM   1255 C CA  . HIS A 1 154 ? 129.371 150.858 104.030 1.00 141.10 ?  161 HIS A CA  1 
ATOM   1256 C C   . HIS A 1 154 ? 128.096 150.607 103.238 1.00 144.88 ?  161 HIS A C   1 
ATOM   1257 O O   . HIS A 1 154 ? 127.654 151.474 102.477 1.00 143.22 ?  161 HIS A O   1 
ATOM   1258 C CB  . HIS A 1 154 ? 130.590 150.546 103.165 1.00 140.21 ?  161 HIS A CB  1 
ATOM   1259 C CG  . HIS A 1 154 ? 130.391 149.388 102.240 1.00 145.46 ?  161 HIS A CG  1 
ATOM   1260 N ND1 . HIS A 1 154 ? 130.400 148.079 102.670 1.00 147.34 ?  161 HIS A ND1 1 
ATOM   1261 C CD2 . HIS A 1 154 ? 130.173 149.343 100.904 1.00 143.04 ?  161 HIS A CD2 1 
ATOM   1262 C CE1 . HIS A 1 154 ? 130.198 147.278 101.640 1.00 144.79 ?  161 HIS A CE1 1 
ATOM   1263 N NE2 . HIS A 1 154 ? 130.057 148.020 100.556 1.00 144.47 ?  161 HIS A NE2 1 
ATOM   1264 N N   . LEU A 1 155 ? 127.493 149.429 103.406 1.00 146.48 ?  162 LEU A N   1 
ATOM   1265 C CA  . LEU A 1 155 ? 126.214 149.116 102.785 1.00 144.35 ?  162 LEU A CA  1 
ATOM   1266 C C   . LEU A 1 155 ? 125.062 149.909 103.382 1.00 146.16 ?  162 LEU A C   1 
ATOM   1267 O O   . LEU A 1 155 ? 123.968 149.899 102.810 1.00 144.51 ?  162 LEU A O   1 
ATOM   1268 C CB  . LEU A 1 155 ? 125.923 147.623 102.919 1.00 140.00 ?  162 LEU A CB  1 
ATOM   1269 C CG  . LEU A 1 155 ? 126.670 146.715 101.949 1.00 140.27 ?  162 LEU A CG  1 
ATOM   1270 C CD1 . LEU A 1 155 ? 127.252 145.526 102.684 1.00 143.57 ?  162 LEU A CD1 1 
ATOM   1271 C CD2 . LEU A 1 155 ? 125.734 146.262 100.851 1.00 140.23 ?  162 LEU A CD2 1 
ATOM   1272 N N   . LEU A 1 156 ? 125.280 150.583 104.509 1.00 148.88 ?  163 LEU A N   1 
ATOM   1273 C CA  . LEU A 1 156 ? 124.230 151.318 105.198 1.00 146.65 ?  163 LEU A CA  1 
ATOM   1274 C C   . LEU A 1 156 ? 124.205 152.800 104.852 1.00 147.60 ?  163 LEU A C   1 
ATOM   1275 O O   . LEU A 1 156 ? 123.137 153.417 104.900 1.00 146.07 ?  163 LEU A O   1 
ATOM   1276 C CB  . LEU A 1 156 ? 124.390 151.155 106.714 1.00 142.94 ?  163 LEU A CB  1 
ATOM   1277 C CG  . LEU A 1 156 ? 123.148 150.798 107.528 1.00 143.09 ?  163 LEU A CG  1 
ATOM   1278 C CD1 . LEU A 1 156 ? 122.311 149.756 106.813 1.00 141.02 ?  163 LEU A CD1 1 
ATOM   1279 C CD2 . LEU A 1 156 ? 123.563 150.295 108.898 1.00 142.56 ?  163 LEU A CD2 1 
ATOM   1280 N N   . LYS A 1 157 ? 125.351 153.389 104.528 1.00 149.58 ?  164 LYS A N   1 
ATOM   1281 C CA  . LYS A 1 157 ? 125.421 154.805 104.171 1.00 150.45 ?  164 LYS A CA  1 
ATOM   1282 C C   . LYS A 1 157 ? 125.434 154.984 102.653 1.00 149.38 ?  164 LYS A C   1 
ATOM   1283 O O   . LYS A 1 157 ? 126.381 155.514 102.071 1.00 149.43 ?  164 LYS A O   1 
ATOM   1284 C CB  . LYS A 1 157 ? 126.644 155.451 104.816 1.00 148.57 ?  164 LYS A CB  1 
ATOM   1285 C CG  . LYS A 1 157 ? 127.844 154.529 104.941 1.00 147.84 ?  164 LYS A CG  1 
ATOM   1286 C CD  . LYS A 1 157 ? 129.133 155.318 105.088 1.00 146.27 ?  164 LYS A CD  1 
ATOM   1287 C CE  . LYS A 1 157 ? 129.497 156.017 103.791 1.00 147.64 ?  164 LYS A CE  1 
ATOM   1288 N NZ  . LYS A 1 157 ? 129.388 155.107 102.619 1.00 146.88 1  164 LYS A NZ  1 
ATOM   1289 N N   . LYS A 1 158 ? 124.358 154.538 102.007 1.00 152.98 ?  165 LYS A N   1 
ATOM   1290 C CA  . LYS A 1 158 ? 124.229 154.694 100.558 1.00 155.44 ?  165 LYS A CA  1 
ATOM   1291 C C   . LYS A 1 158 ? 122.770 154.520 100.171 1.00 157.20 ?  165 LYS A C   1 
ATOM   1292 O O   . LYS A 1 158 ? 122.153 153.518 100.541 1.00 158.44 ?  165 LYS A O   1 
ATOM   1293 C CB  . LYS A 1 158 ? 125.108 153.682 99.823  1.00 153.68 ?  165 LYS A CB  1 
ATOM   1294 C CG  . LYS A 1 158 ? 125.112 153.847 98.315  1.00 152.40 ?  165 LYS A CG  1 
ATOM   1295 C CD  . LYS A 1 158 ? 124.451 152.666 97.628  1.00 153.72 ?  165 LYS A CD  1 
ATOM   1296 C CE  . LYS A 1 158 ? 125.494 151.711 97.077  1.00 154.51 ?  165 LYS A CE  1 
ATOM   1297 N NZ  . LYS A 1 158 ? 124.887 150.590 96.312  1.00 152.32 1  165 LYS A NZ  1 
ATOM   1298 N N   . LYS A 1 159 ? 122.223 155.478 99.421  1.00 162.90 ?  166 LYS A N   1 
ATOM   1299 C CA  . LYS A 1 159 ? 120.833 155.386 98.986  1.00 163.24 ?  166 LYS A CA  1 
ATOM   1300 C C   . LYS A 1 159 ? 120.664 154.200 98.046  1.00 161.91 ?  166 LYS A C   1 
ATOM   1301 O O   . LYS A 1 159 ? 121.082 154.248 96.885  1.00 159.32 ?  166 LYS A O   1 
ATOM   1302 C CB  . LYS A 1 159 ? 120.388 156.684 98.307  1.00 161.10 ?  166 LYS A CB  1 
ATOM   1303 C CG  . LYS A 1 159 ? 120.894 157.950 98.983  1.00 160.67 ?  166 LYS A CG  1 
ATOM   1304 C CD  . LYS A 1 159 ? 120.456 158.021 100.438 1.00 160.71 ?  166 LYS A CD  1 
ATOM   1305 C CE  . LYS A 1 159 ? 121.185 159.128 101.182 1.00 159.42 ?  166 LYS A CE  1 
ATOM   1306 N NZ  . LYS A 1 159 ? 120.408 159.617 102.352 1.00 158.09 1  166 LYS A NZ  1 
ATOM   1307 N N   . MET A 1 160 ? 120.047 153.134 98.546  1.00 166.10 ?  167 MET A N   1 
ATOM   1308 C CA  . MET A 1 160 ? 120.045 151.833 97.886  1.00 167.91 ?  167 MET A CA  1 
ATOM   1309 C C   . MET A 1 160 ? 119.025 151.686 96.756  1.00 169.52 ?  167 MET A C   1 
ATOM   1310 O O   . MET A 1 160 ? 119.407 151.241 95.666  1.00 166.77 ?  167 MET A O   1 
ATOM   1311 C CB  . MET A 1 160 ? 119.830 150.736 98.935  1.00 165.70 ?  167 MET A CB  1 
ATOM   1312 C CG  . MET A 1 160 ? 119.569 149.309 98.427  1.00 165.96 ?  167 MET A CG  1 
ATOM   1313 S SD  . MET A 1 160 ? 120.283 148.572 96.926  1.00 168.99 ?  167 MET A SD  1 
ATOM   1314 C CE  . MET A 1 160 ? 121.913 149.301 96.785  1.00 166.06 ?  167 MET A CE  1 
ATOM   1315 N N   . PRO A 1 161 ? 117.722 152.036 96.953  1.00 173.72 ?  168 PRO A N   1 
ATOM   1316 C CA  . PRO A 1 161 ? 116.709 151.680 95.943  1.00 171.35 ?  168 PRO A CA  1 
ATOM   1317 C C   . PRO A 1 161 ? 117.077 152.066 94.521  1.00 172.54 ?  168 PRO A C   1 
ATOM   1318 O O   . PRO A 1 161 ? 117.219 153.250 94.200  1.00 171.76 ?  168 PRO A O   1 
ATOM   1319 C CB  . PRO A 1 161 ? 115.466 152.447 96.408  1.00 170.65 ?  168 PRO A CB  1 
ATOM   1320 C CG  . PRO A 1 161 ? 115.632 152.579 97.847  1.00 169.28 ?  168 PRO A CG  1 
ATOM   1321 C CD  . PRO A 1 161 ? 117.104 152.712 98.108  1.00 170.80 ?  168 PRO A CD  1 
ATOM   1322 N N   . ILE A 1 162 ? 117.232 151.063 93.665  1.00 177.44 ?  169 ILE A N   1 
ATOM   1323 C CA  . ILE A 1 162 ? 117.599 151.259 92.269  1.00 177.39 ?  169 ILE A CA  1 
ATOM   1324 C C   . ILE A 1 162 ? 116.352 151.027 91.428  1.00 178.05 ?  169 ILE A C   1 
ATOM   1325 O O   . ILE A 1 162 ? 115.804 149.920 91.404  1.00 176.74 ?  169 ILE A O   1 
ATOM   1326 C CB  . ILE A 1 162 ? 118.734 150.318 91.848  1.00 177.09 ?  169 ILE A CB  1 
ATOM   1327 C CG1 . ILE A 1 162 ? 120.056 150.768 92.470  1.00 175.81 ?  169 ILE A CG1 1 
ATOM   1328 C CG2 . ILE A 1 162 ? 118.828 150.258 90.334  1.00 176.78 ?  169 ILE A CG2 1 
ATOM   1329 C CD1 . ILE A 1 162 ? 120.809 149.654 93.167  1.00 174.64 ?  169 ILE A CD1 1 
ATOM   1330 N N   . GLN A 1 163 ? 115.903 152.066 90.730  1.00 185.26 ?  170 GLN A N   1 
ATOM   1331 C CA  . GLN A 1 163 ? 114.684 151.984 89.927  1.00 186.71 ?  170 GLN A CA  1 
ATOM   1332 C C   . GLN A 1 163 ? 115.002 151.523 88.504  1.00 186.84 ?  170 GLN A C   1 
ATOM   1333 O O   . GLN A 1 163 ? 114.896 152.269 87.531  1.00 186.33 ?  170 GLN A O   1 
ATOM   1334 C CB  . GLN A 1 163 ? 113.958 153.324 89.933  1.00 186.21 ?  170 GLN A CB  1 
ATOM   1335 C CG  . GLN A 1 163 ? 113.410 153.714 91.296  1.00 186.96 ?  170 GLN A CG  1 
ATOM   1336 C CD  . GLN A 1 163 ? 112.628 155.011 91.262  1.00 186.57 ?  170 GLN A CD  1 
ATOM   1337 O OE1 . GLN A 1 163 ? 112.827 155.847 90.382  1.00 185.79 ?  170 GLN A OE1 1 
ATOM   1338 N NE2 . GLN A 1 163 ? 111.734 155.187 92.228  1.00 185.49 ?  170 GLN A NE2 1 
ATOM   1339 N N   . ASN A 1 164 ? 115.402 150.257 88.400  1.00 185.41 ?  171 ASN A N   1 
ATOM   1340 C CA  . ASN A 1 164 ? 115.620 149.625 87.102  1.00 185.63 ?  171 ASN A CA  1 
ATOM   1341 C C   . ASN A 1 164 ? 114.282 149.445 86.399  1.00 186.07 ?  171 ASN A C   1 
ATOM   1342 O O   . ASN A 1 164 ? 113.540 148.503 86.696  1.00 186.29 ?  171 ASN A O   1 
ATOM   1343 C CB  . ASN A 1 164 ? 116.325 148.284 87.281  1.00 185.20 ?  171 ASN A CB  1 
ATOM   1344 C CG  . ASN A 1 164 ? 116.676 147.627 85.961  1.00 185.32 ?  171 ASN A CG  1 
ATOM   1345 O OD1 . ASN A 1 164 ? 117.589 148.068 85.262  1.00 185.44 ?  171 ASN A OD1 1 
ATOM   1346 N ND2 . ASN A 1 164 ? 115.960 146.568 85.614  1.00 184.08 ?  171 ASN A ND2 1 
ATOM   1347 N N   . GLY A 1 165 ? 113.981 150.334 85.455  1.00 180.67 ?  172 GLY A N   1 
ATOM   1348 C CA  . GLY A 1 165 ? 112.693 150.283 84.788  1.00 179.89 ?  172 GLY A CA  1 
ATOM   1349 C C   . GLY A 1 165 ? 111.561 150.402 85.787  1.00 181.33 ?  172 GLY A C   1 
ATOM   1350 O O   . GLY A 1 165 ? 111.553 151.281 86.656  1.00 180.50 ?  172 GLY A O   1 
ATOM   1351 N N   . GLY A 1 166 ? 110.588 149.505 85.665  1.00 184.17 ?  173 GLY A N   1 
ATOM   1352 C CA  . GLY A 1 166 ? 109.525 149.411 86.645  1.00 183.42 ?  173 GLY A CA  1 
ATOM   1353 C C   . GLY A 1 166 ? 109.833 148.388 87.718  1.00 185.33 ?  173 GLY A C   1 
ATOM   1354 O O   . GLY A 1 166 ? 109.008 147.517 88.010  1.00 184.51 ?  173 GLY A O   1 
ATOM   1355 N N   . ALA A 1 167 ? 111.022 148.481 88.312  1.00 183.26 ?  174 ALA A N   1 
ATOM   1356 C CA  . ALA A 1 167 ? 111.461 147.510 89.303  1.00 180.62 ?  174 ALA A CA  1 
ATOM   1357 C C   . ALA A 1 167 ? 112.440 148.169 90.262  1.00 179.72 ?  174 ALA A C   1 
ATOM   1358 O O   . ALA A 1 167 ? 113.194 149.064 89.873  1.00 178.90 ?  174 ALA A O   1 
ATOM   1359 C CB  . ALA A 1 167 ? 112.119 146.295 88.639  1.00 178.63 ?  174 ALA A CB  1 
ATOM   1360 N N   . ASN A 1 168 ? 112.421 147.718 91.512  1.00 172.99 ?  175 ASN A N   1 
ATOM   1361 C CA  . ASN A 1 168 ? 113.367 148.162 92.527  1.00 174.43 ?  175 ASN A CA  1 
ATOM   1362 C C   . ASN A 1 168 ? 114.391 147.056 92.751  1.00 174.08 ?  175 ASN A C   1 
ATOM   1363 O O   . ASN A 1 168 ? 114.023 145.924 93.082  1.00 175.53 ?  175 ASN A O   1 
ATOM   1364 C CB  . ASN A 1 168 ? 112.649 148.507 93.831  1.00 174.94 ?  175 ASN A CB  1 
ATOM   1365 C CG  . ASN A 1 168 ? 113.270 149.690 94.543  1.00 174.24 ?  175 ASN A CG  1 
ATOM   1366 O OD1 . ASN A 1 168 ? 113.404 150.772 93.973  1.00 173.73 ?  175 ASN A OD1 1 
ATOM   1367 N ND2 . ASN A 1 168 ? 113.650 149.491 95.799  1.00 171.45 ?  175 ASN A ND2 1 
ATOM   1368 N N   . LEU A 1 169 ? 115.668 147.383 92.576  1.00 167.76 ?  176 LEU A N   1 
ATOM   1369 C CA  . LEU A 1 169 ? 116.748 146.405 92.664  1.00 168.20 ?  176 LEU A CA  1 
ATOM   1370 C C   . LEU A 1 169 ? 117.377 146.475 94.050  1.00 166.84 ?  176 LEU A C   1 
ATOM   1371 O O   . LEU A 1 169 ? 118.099 147.424 94.366  1.00 168.36 ?  176 LEU A O   1 
ATOM   1372 C CB  . LEU A 1 169 ? 117.791 146.649 91.575  1.00 168.70 ?  176 LEU A CB  1 
ATOM   1373 C CG  . LEU A 1 169 ? 117.666 145.822 90.292  1.00 168.18 ?  176 LEU A CG  1 
ATOM   1374 C CD1 . LEU A 1 169 ? 118.253 144.438 90.499  1.00 167.34 ?  176 LEU A CD1 1 
ATOM   1375 C CD2 . LEU A 1 169 ? 116.221 145.721 89.831  1.00 168.54 ?  176 LEU A CD2 1 
ATOM   1376 N N   . CYS A 1 170 ? 117.103 145.467 94.871  1.00 161.65 ?  177 CYS A N   1 
ATOM   1377 C CA  . CYS A 1 170 ? 117.720 145.336 96.189  1.00 160.41 ?  177 CYS A CA  1 
ATOM   1378 C C   . CYS A 1 170 ? 118.989 144.495 96.121  1.00 164.39 ?  177 CYS A C   1 
ATOM   1379 O O   . CYS A 1 170 ? 119.157 143.531 96.864  1.00 167.76 ?  177 CYS A O   1 
ATOM   1380 C CB  . CYS A 1 170 ? 116.722 144.734 97.169  1.00 166.10 ?  177 CYS A CB  1 
ATOM   1381 S SG  . CYS A 1 170 ? 117.171 144.926 98.902  1.00 179.90 ?  177 CYS A SG  1 
ATOM   1382 N N   . SER A 1 171 ? 119.897 144.863 95.223  1.00 158.04 ?  178 SER A N   1 
ATOM   1383 C CA  . SER A 1 171 ? 121.094 144.082 94.953  1.00 153.76 ?  178 SER A CA  1 
ATOM   1384 C C   . SER A 1 171 ? 122.334 144.838 95.400  1.00 151.52 ?  178 SER A C   1 
ATOM   1385 O O   . SER A 1 171 ? 122.511 146.014 95.070  1.00 152.76 ?  178 SER A O   1 
ATOM   1386 C CB  . SER A 1 171 ? 121.207 143.750 93.463  1.00 150.80 ?  178 SER A CB  1 
ATOM   1387 O OG  . SER A 1 171 ? 120.079 143.023 93.012  1.00 153.50 ?  178 SER A OG  1 
ATOM   1388 N N   . SER A 1 172 ? 123.195 144.151 96.151  1.00 141.13 ?  179 SER A N   1 
ATOM   1389 C CA  . SER A 1 172 ? 124.506 144.674 96.496  1.00 143.55 ?  179 SER A CA  1 
ATOM   1390 C C   . SER A 1 172 ? 125.623 144.091 95.648  1.00 145.76 ?  179 SER A C   1 
ATOM   1391 O O   . SER A 1 172 ? 126.665 144.735 95.500  1.00 143.63 ?  179 SER A O   1 
ATOM   1392 C CB  . SER A 1 172 ? 124.819 144.407 97.973  1.00 140.92 ?  179 SER A CB  1 
ATOM   1393 O OG  . SER A 1 172 ? 125.325 143.098 98.154  1.00 141.81 ?  179 SER A OG  1 
ATOM   1394 N N   . PHE A 1 173 ? 125.432 142.893 95.128  1.00 143.85 ?  180 PHE A N   1 
ATOM   1395 C CA  . PHE A 1 173 ? 126.419 142.279 94.277  1.00 140.58 ?  180 PHE A CA  1 
ATOM   1396 C C   . PHE A 1 173 ? 125.913 142.374 92.855  1.00 143.69 ?  180 PHE A C   1 
ATOM   1397 O O   . PHE A 1 173 ? 125.046 141.595 92.457  1.00 144.94 ?  180 PHE A O   1 
ATOM   1398 C CB  . PHE A 1 173 ? 126.594 140.815 94.659  1.00 137.94 ?  180 PHE A CB  1 
ATOM   1399 C CG  . PHE A 1 173 ? 127.509 140.592 95.820  1.00 136.39 ?  180 PHE A CG  1 
ATOM   1400 C CD1 . PHE A 1 173 ? 128.769 141.149 95.839  1.00 135.53 ?  180 PHE A CD1 1 
ATOM   1401 C CD2 . PHE A 1 173 ? 127.109 139.817 96.888  1.00 140.03 ?  180 PHE A CD2 1 
ATOM   1402 C CE1 . PHE A 1 173 ? 129.613 140.941 96.907  1.00 136.72 ?  180 PHE A CE1 1 
ATOM   1403 C CE2 . PHE A 1 173 ? 127.945 139.605 97.960  1.00 139.65 ?  180 PHE A CE2 1 
ATOM   1404 C CZ  . PHE A 1 173 ? 129.200 140.170 97.970  1.00 139.04 ?  180 PHE A CZ  1 
ATOM   1405 N N   . SER A 1 174 ? 126.440 143.328 92.098  1.00 159.12 ?  181 SER A N   1 
ATOM   1406 C CA  . SER A 1 174 ? 126.021 143.492 90.713  1.00 159.16 ?  181 SER A CA  1 
ATOM   1407 C C   . SER A 1 174 ? 127.270 143.274 89.882  1.00 162.79 ?  181 SER A C   1 
ATOM   1408 O O   . SER A 1 174 ? 128.185 142.596 90.335  1.00 163.40 ?  181 SER A O   1 
ATOM   1409 C CB  . SER A 1 174 ? 125.572 144.919 90.458  1.00 158.71 ?  181 SER A CB  1 
ATOM   1410 O OG  . SER A 1 174 ? 124.160 144.994 90.442  1.00 158.96 ?  181 SER A OG  1 
ATOM   1411 N N   . ILE A 1 175 ? 127.342 143.847 88.683  1.00 165.44 ?  182 ILE A N   1 
ATOM   1412 C CA  . ILE A 1 175 ? 128.478 143.577 87.804  1.00 165.61 ?  182 ILE A CA  1 
ATOM   1413 C C   . ILE A 1 175 ? 129.378 144.698 87.268  1.00 166.41 ?  182 ILE A C   1 
ATOM   1414 O O   . ILE A 1 175 ? 130.163 144.461 86.357  1.00 167.24 ?  182 ILE A O   1 
ATOM   1415 C CB  . ILE A 1 175 ? 127.784 142.950 86.574  1.00 163.57 ?  182 ILE A CB  1 
ATOM   1416 C CG1 . ILE A 1 175 ? 126.926 141.761 86.982  1.00 163.18 ?  182 ILE A CG1 1 
ATOM   1417 C CG2 . ILE A 1 175 ? 128.787 142.464 85.543  1.00 165.52 ?  182 ILE A CG2 1 
ATOM   1418 C CD1 . ILE A 1 175 ? 127.729 140.492 87.153  1.00 163.78 ?  182 ILE A CD1 1 
ATOM   1419 N N   . CYS A 1 176 ? 129.226 145.884 87.856  1.00 179.97 ?  183 CYS A N   1 
ATOM   1420 C CA  . CYS A 1 176 ? 130.010 147.027 87.421  1.00 183.19 ?  183 CYS A CA  1 
ATOM   1421 C C   . CYS A 1 176 ? 131.467 146.756 87.676  1.00 183.23 ?  183 CYS A C   1 
ATOM   1422 O O   . CYS A 1 176 ? 131.801 145.901 88.488  1.00 181.23 ?  183 CYS A O   1 
ATOM   1423 C CB  . CYS A 1 176 ? 129.567 148.316 88.133  1.00 185.94 ?  183 CYS A CB  1 
ATOM   1424 S SG  . CYS A 1 176 ? 127.874 148.402 88.790  1.00 191.57 ?  183 CYS A SG  1 
ATOM   1425 N N   . HIS A 1 177 ? 132.346 147.497 87.021  1.00 185.20 ?  184 HIS A N   1 
ATOM   1426 C CA  . HIS A 1 177 ? 133.771 147.214 87.129  1.00 184.71 ?  184 HIS A CA  1 
ATOM   1427 C C   . HIS A 1 177 ? 134.427 147.525 88.471  1.00 184.68 ?  184 HIS A C   1 
ATOM   1428 O O   . HIS A 1 177 ? 135.184 146.703 88.978  1.00 183.71 ?  184 HIS A O   1 
ATOM   1429 C CB  . HIS A 1 177 ? 134.510 147.960 86.011  1.00 183.53 ?  184 HIS A CB  1 
ATOM   1430 C CG  . HIS A 1 177 ? 135.133 149.245 86.452  1.00 184.50 ?  184 HIS A CG  1 
ATOM   1431 N ND1 . HIS A 1 177 ? 134.415 150.415 86.575  1.00 184.61 ?  184 HIS A ND1 1 
ATOM   1432 C CD2 . HIS A 1 177 ? 136.401 149.540 86.823  1.00 184.58 ?  184 HIS A CD2 1 
ATOM   1433 C CE1 . HIS A 1 177 ? 135.217 151.378 86.992  1.00 184.31 ?  184 HIS A CE1 1 
ATOM   1434 N NE2 . HIS A 1 177 ? 136.427 150.874 87.150  1.00 185.79 ?  184 HIS A NE2 1 
ATOM   1435 N N   . THR A 1 178 ? 134.153 148.684 89.052  1.00 177.91 ?  185 THR A N   1 
ATOM   1436 C CA  . THR A 1 178 ? 134.836 149.096 90.289  1.00 177.31 ?  185 THR A CA  1 
ATOM   1437 C C   . THR A 1 178 ? 135.133 148.050 91.374  1.00 176.77 ?  185 THR A C   1 
ATOM   1438 O O   . THR A 1 178 ? 134.230 147.370 91.846  1.00 177.11 ?  185 THR A O   1 
ATOM   1439 C CB  . THR A 1 178 ? 134.013 150.187 91.001  1.00 176.66 ?  185 THR A CB  1 
ATOM   1440 O OG1 . THR A 1 178 ? 134.036 151.384 90.215  1.00 176.95 ?  185 THR A OG1 1 
ATOM   1441 C CG2 . THR A 1 178 ? 134.576 150.481 92.383  1.00 174.79 ?  185 THR A CG2 1 
ATOM   1442 N N   . PHE A 1 179 ? 136.398 147.926 91.770  1.00 166.76 ?  186 PHE A N   1 
ATOM   1443 C CA  . PHE A 1 179 ? 136.748 147.000 92.850  1.00 167.20 ?  186 PHE A CA  1 
ATOM   1444 C C   . PHE A 1 179 ? 136.409 147.521 94.233  1.00 166.84 ?  186 PHE A C   1 
ATOM   1445 O O   . PHE A 1 179 ? 137.293 147.708 95.062  1.00 164.12 ?  186 PHE A O   1 
ATOM   1446 C CB  . PHE A 1 179 ? 138.205 146.583 92.742  1.00 165.38 ?  186 PHE A CB  1 
ATOM   1447 C CG  . PHE A 1 179 ? 138.398 145.102 92.852  1.00 166.09 ?  186 PHE A CG  1 
ATOM   1448 C CD1 . PHE A 1 179 ? 138.037 144.435 94.010  1.00 165.99 ?  186 PHE A CD1 1 
ATOM   1449 C CD2 . PHE A 1 179 ? 138.902 144.373 91.792  1.00 164.95 ?  186 PHE A CD2 1 
ATOM   1450 C CE1 . PHE A 1 179 ? 138.197 143.069 94.117  1.00 165.69 ?  186 PHE A CE1 1 
ATOM   1451 C CE2 . PHE A 1 179 ? 139.065 143.005 91.892  1.00 166.15 ?  186 PHE A CE2 1 
ATOM   1452 C CZ  . PHE A 1 179 ? 138.713 142.353 93.056  1.00 166.15 ?  186 PHE A CZ  1 
ATOM   1453 N N   . GLN A 1 180 ? 135.136 147.754 94.480  1.00 164.25 ?  187 GLN A N   1 
ATOM   1454 C CA  . GLN A 1 180 ? 134.619 148.227 95.752  1.00 163.00 ?  187 GLN A CA  1 
ATOM   1455 C C   . GLN A 1 180 ? 134.891 147.206 96.854  1.00 163.29 ?  187 GLN A C   1 
ATOM   1456 O O   . GLN A 1 180 ? 135.161 146.029 96.599  1.00 160.92 ?  187 GLN A O   1 
ATOM   1457 C CB  . GLN A 1 180 ? 133.120 148.510 95.654  1.00 161.67 ?  187 GLN A CB  1 
ATOM   1458 C CG  . GLN A 1 180 ? 132.284 147.314 95.229  1.00 162.01 ?  187 GLN A CG  1 
ATOM   1459 C CD  . GLN A 1 180 ? 131.897 147.365 93.765  1.00 161.91 ?  187 GLN A CD  1 
ATOM   1460 O OE1 . GLN A 1 180 ? 131.979 146.366 93.052  1.00 160.30 ?  187 GLN A OE1 1 
ATOM   1461 N NE2 . GLN A 1 180 ? 131.470 148.536 93.308  1.00 162.42 ?  187 GLN A NE2 1 
ATOM   1462 N N   . TRP A 1 181 ? 134.819 147.679 98.100  1.00 153.51 ?  188 TRP A N   1 
ATOM   1463 C CA  . TRP A 1 181 ? 135.096 146.816 99.241  1.00 151.21 ?  188 TRP A CA  1 
ATOM   1464 C C   . TRP A 1 181 ? 134.118 145.654 99.337  1.00 151.98 ?  188 TRP A C   1 
ATOM   1465 O O   . TRP A 1 181 ? 134.469 144.612 99.895  1.00 153.50 ?  188 TRP A O   1 
ATOM   1466 C CB  . TRP A 1 181 ? 135.076 147.633 100.534 1.00 149.50 ?  188 TRP A CB  1 
ATOM   1467 C CG  . TRP A 1 181 ? 135.975 147.091 101.612 1.00 152.70 ?  188 TRP A CG  1 
ATOM   1468 C CD1 . TRP A 1 181 ? 136.396 145.802 101.759 1.00 151.70 ?  188 TRP A CD1 1 
ATOM   1469 C CD2 . TRP A 1 181 ? 136.574 147.832 102.682 1.00 156.83 ?  188 TRP A CD2 1 
ATOM   1470 N NE1 . TRP A 1 181 ? 137.210 145.691 102.859 1.00 150.69 ?  188 TRP A NE1 1 
ATOM   1471 C CE2 . TRP A 1 181 ? 137.336 146.924 103.443 1.00 155.36 ?  188 TRP A CE2 1 
ATOM   1472 C CE3 . TRP A 1 181 ? 136.537 149.174 103.073 1.00 154.52 ?  188 TRP A CE3 1 
ATOM   1473 C CZ2 . TRP A 1 181 ? 138.057 147.314 104.571 1.00 152.32 ?  188 TRP A CZ2 1 
ATOM   1474 C CZ3 . TRP A 1 181 ? 137.252 149.560 104.194 1.00 152.25 ?  188 TRP A CZ3 1 
ATOM   1475 C CH2 . TRP A 1 181 ? 138.001 148.633 104.930 1.00 151.03 ?  188 TRP A CH2 1 
ATOM   1476 N N   . HIS A 1 182 ? 132.911 145.792 98.788  1.00 147.69 ?  189 HIS A N   1 
ATOM   1477 C CA  . HIS A 1 182 ? 131.953 144.695 98.844  1.00 147.67 ?  189 HIS A CA  1 
ATOM   1478 C C   . HIS A 1 182 ? 132.386 143.493 98.018  1.00 151.34 ?  189 HIS A C   1 
ATOM   1479 O O   . HIS A 1 182 ? 131.786 142.422 98.158  1.00 153.36 ?  189 HIS A O   1 
ATOM   1480 C CB  . HIS A 1 182 ? 130.576 145.168 98.383  1.00 146.98 ?  189 HIS A CB  1 
ATOM   1481 C CG  . HIS A 1 182 ? 129.453 144.291 98.843  1.00 148.85 ?  189 HIS A CG  1 
ATOM   1482 N ND1 . HIS A 1 182 ? 129.277 143.941 100.164 1.00 150.43 ?  189 HIS A ND1 1 
ATOM   1483 C CD2 . HIS A 1 182 ? 128.449 143.695 98.159  1.00 148.92 ?  189 HIS A CD2 1 
ATOM   1484 C CE1 . HIS A 1 182 ? 128.212 143.167 100.274 1.00 148.10 ?  189 HIS A CE1 1 
ATOM   1485 N NE2 . HIS A 1 182 ? 127.691 143.003 99.072  1.00 148.44 ?  189 HIS A NE2 1 
ATOM   1486 N N   . GLU A 1 183 ? 133.398 143.638 97.163  1.00 146.95 ?  190 GLU A N   1 
ATOM   1487 C CA  . GLU A 1 183 ? 133.943 142.526 96.396  1.00 145.64 ?  190 GLU A CA  1 
ATOM   1488 C C   . GLU A 1 183 ? 135.259 142.018 96.971  1.00 145.09 ?  190 GLU A C   1 
ATOM   1489 O O   . GLU A 1 183 ? 135.469 140.804 97.075  1.00 143.84 ?  190 GLU A O   1 
ATOM   1490 C CB  . GLU A 1 183 ? 134.138 142.943 94.935  1.00 145.13 ?  190 GLU A CB  1 
ATOM   1491 C CG  . GLU A 1 183 ? 132.886 143.490 94.269  1.00 146.49 ?  190 GLU A CG  1 
ATOM   1492 C CD  . GLU A 1 183 ? 131.887 142.410 93.900  1.00 146.71 ?  190 GLU A CD  1 
ATOM   1493 O OE1 . GLU A 1 183 ? 132.131 141.226 94.210  1.00 144.84 ?  190 GLU A OE1 1 
ATOM   1494 O OE2 . GLU A 1 183 ? 130.852 142.749 93.291  1.00 146.52 -1 190 GLU A OE2 1 
ATOM   1495 N N   . ALA A 1 184 ? 136.154 142.932 97.349  1.00 143.89 ?  191 ALA A N   1 
ATOM   1496 C CA  . ALA A 1 184 ? 137.404 142.519 97.975  1.00 145.66 ?  191 ALA A CA  1 
ATOM   1497 C C   . ALA A 1 184 ? 137.143 141.808 99.295  1.00 143.17 ?  191 ALA A C   1 
ATOM   1498 O O   . ALA A 1 184 ? 137.762 140.779 99.584  1.00 141.37 ?  191 ALA A O   1 
ATOM   1499 C CB  . ALA A 1 184 ? 138.316 143.727 98.184  1.00 144.20 ?  191 ALA A CB  1 
ATOM   1500 N N   . MET A 1 185 ? 136.226 142.340 100.106 1.00 134.79 ?  192 MET A N   1 
ATOM   1501 C CA  . MET A 1 185 ? 135.864 141.672 101.350 1.00 135.85 ?  192 MET A CA  1 
ATOM   1502 C C   . MET A 1 185 ? 135.206 140.328 101.073 1.00 136.38 ?  192 MET A C   1 
ATOM   1503 O O   . MET A 1 185 ? 135.461 139.348 101.780 1.00 137.88 ?  192 MET A O   1 
ATOM   1504 C CB  . MET A 1 185 ? 134.940 142.565 102.179 1.00 134.04 ?  192 MET A CB  1 
ATOM   1505 C CG  . MET A 1 185 ? 134.026 141.807 103.124 1.00 134.57 ?  192 MET A CG  1 
ATOM   1506 S SD  . MET A 1 185 ? 132.679 142.807 103.782 1.00 142.81 ?  192 MET A SD  1 
ATOM   1507 C CE  . MET A 1 185 ? 131.406 142.517 102.558 1.00 135.90 ?  192 MET A CE  1 
ATOM   1508 N N   . PHE A 1 186 ? 134.366 140.261 100.040 1.00 129.18 ?  193 PHE A N   1 
ATOM   1509 C CA  . PHE A 1 186 ? 133.705 139.005 99.702  1.00 129.62 ?  193 PHE A CA  1 
ATOM   1510 C C   . PHE A 1 186 ? 134.715 137.929 99.330  1.00 134.47 ?  193 PHE A C   1 
ATOM   1511 O O   . PHE A 1 186 ? 134.562 136.763 99.709  1.00 138.45 ?  193 PHE A O   1 
ATOM   1512 C CB  . PHE A 1 186 ? 132.718 139.226 98.559  1.00 127.35 ?  193 PHE A CB  1 
ATOM   1513 C CG  . PHE A 1 186 ? 132.079 137.968 98.058  1.00 129.31 ?  193 PHE A CG  1 
ATOM   1514 C CD1 . PHE A 1 186 ? 131.251 137.224 98.877  1.00 127.99 ?  193 PHE A CD1 1 
ATOM   1515 C CD2 . PHE A 1 186 ? 132.301 137.532 96.766  1.00 128.37 ?  193 PHE A CD2 1 
ATOM   1516 C CE1 . PHE A 1 186 ? 130.659 136.070 98.414  1.00 128.62 ?  193 PHE A CE1 1 
ATOM   1517 C CE2 . PHE A 1 186 ? 131.712 136.379 96.300  1.00 128.43 ?  193 PHE A CE2 1 
ATOM   1518 C CZ  . PHE A 1 186 ? 130.890 135.648 97.124  1.00 129.37 ?  193 PHE A CZ  1 
ATOM   1519 N N   . LEU A 1 187 ? 135.749 138.295 98.574  1.00 130.72 ?  194 LEU A N   1 
ATOM   1520 C CA  . LEU A 1 187 ? 136.760 137.309 98.207  1.00 128.96 ?  194 LEU A CA  1 
ATOM   1521 C C   . LEU A 1 187 ? 137.658 136.965 99.392  1.00 132.05 ?  194 LEU A C   1 
ATOM   1522 O O   . LEU A 1 187 ? 138.005 135.793 99.597  1.00 133.05 ?  194 LEU A O   1 
ATOM   1523 C CB  . LEU A 1 187 ? 137.586 137.819 97.029  1.00 129.05 ?  194 LEU A CB  1 
ATOM   1524 C CG  . LEU A 1 187 ? 137.049 137.424 95.653  1.00 129.56 ?  194 LEU A CG  1 
ATOM   1525 C CD1 . LEU A 1 187 ? 137.945 137.959 94.552  1.00 128.30 ?  194 LEU A CD1 1 
ATOM   1526 C CD2 . LEU A 1 187 ? 136.915 135.916 95.550  1.00 127.59 ?  194 LEU A CD2 1 
ATOM   1527 N N   . LEU A 1 188 ? 138.043 137.971 100.183 1.00 131.35 ?  195 LEU A N   1 
ATOM   1528 C CA  . LEU A 1 188 ? 138.940 137.736 101.309 1.00 129.10 ?  195 LEU A CA  1 
ATOM   1529 C C   . LEU A 1 188 ? 138.291 136.853 102.364 1.00 128.53 ?  195 LEU A C   1 
ATOM   1530 O O   . LEU A 1 188 ? 138.946 135.962 102.918 1.00 131.40 ?  195 LEU A O   1 
ATOM   1531 C CB  . LEU A 1 188 ? 139.374 139.067 101.918 1.00 126.81 ?  195 LEU A CB  1 
ATOM   1532 C CG  . LEU A 1 188 ? 140.838 139.160 102.352 1.00 129.88 ?  195 LEU A CG  1 
ATOM   1533 C CD1 . LEU A 1 188 ? 141.729 139.454 101.158 1.00 130.04 ?  195 LEU A CD1 1 
ATOM   1534 C CD2 . LEU A 1 188 ? 141.014 140.218 103.429 1.00 127.55 ?  195 LEU A CD2 1 
ATOM   1535 N N   . GLU A 1 189 ? 137.002 137.069 102.643 1.00 123.18 ?  196 GLU A N   1 
ATOM   1536 C CA  . GLU A 1 189 ? 136.287 136.297 103.649 1.00 120.99 ?  196 GLU A CA  1 
ATOM   1537 C C   . GLU A 1 189 ? 136.122 134.838 103.261 1.00 123.28 ?  196 GLU A C   1 
ATOM   1538 O O   . GLU A 1 189 ? 135.700 134.038 104.098 1.00 129.75 ?  196 GLU A O   1 
ATOM   1539 C CB  . GLU A 1 189 ? 134.913 136.913 103.912 1.00 120.58 ?  196 GLU A CB  1 
ATOM   1540 C CG  . GLU A 1 189 ? 133.943 136.753 102.761 1.00 125.52 ?  196 GLU A CG  1 
ATOM   1541 C CD  . GLU A 1 189 ? 132.497 136.864 103.186 1.00 131.66 ?  196 GLU A CD  1 
ATOM   1542 O OE1 . GLU A 1 189 ? 132.211 137.635 104.126 1.00 131.67 ?  196 GLU A OE1 1 
ATOM   1543 O OE2 . GLU A 1 189 ? 131.644 136.189 102.573 1.00 129.03 -1 196 GLU A OE2 1 
ATOM   1544 N N   . PHE A 1 190 ? 136.405 134.477 102.014 1.00 118.64 ?  197 PHE A N   1 
ATOM   1545 C CA  . PHE A 1 190 ? 136.550 133.065 101.703 1.00 121.06 ?  197 PHE A CA  1 
ATOM   1546 C C   . PHE A 1 190 ? 138.010 132.637 101.728 1.00 123.19 ?  197 PHE A C   1 
ATOM   1547 O O   . PHE A 1 190 ? 138.335 131.590 102.286 1.00 125.57 ?  197 PHE A O   1 
ATOM   1548 C CB  . PHE A 1 190 ? 135.949 132.733 100.340 1.00 122.13 ?  197 PHE A CB  1 
ATOM   1549 C CG  . PHE A 1 190 ? 136.309 131.359 99.849  1.00 122.86 ?  197 PHE A CG  1 
ATOM   1550 C CD1 . PHE A 1 190 ? 135.679 130.243 100.363 1.00 122.02 ?  197 PHE A CD1 1 
ATOM   1551 C CD2 . PHE A 1 190 ? 137.291 131.183 98.893  1.00 121.85 ?  197 PHE A CD2 1 
ATOM   1552 C CE1 . PHE A 1 190 ? 136.007 128.980 99.922  1.00 122.06 ?  197 PHE A CE1 1 
ATOM   1553 C CE2 . PHE A 1 190 ? 137.624 129.922 98.448  1.00 122.95 ?  197 PHE A CE2 1 
ATOM   1554 C CZ  . PHE A 1 190 ? 136.980 128.819 98.963  1.00 123.63 ?  197 PHE A CZ  1 
ATOM   1555 N N   . PHE A 1 191 ? 138.899 133.436 101.136 1.00 122.97 ?  198 PHE A N   1 
ATOM   1556 C CA  . PHE A 1 191 ? 140.279 132.991 100.953 1.00 121.66 ?  198 PHE A CA  1 
ATOM   1557 C C   . PHE A 1 191 ? 141.029 132.904 102.278 1.00 120.87 ?  198 PHE A C   1 
ATOM   1558 O O   . PHE A 1 191 ? 141.518 131.834 102.656 1.00 120.39 ?  198 PHE A O   1 
ATOM   1559 C CB  . PHE A 1 191 ? 141.004 133.913 99.974  1.00 120.52 ?  198 PHE A CB  1 
ATOM   1560 C CG  . PHE A 1 191 ? 140.884 133.480 98.545  1.00 123.50 ?  198 PHE A CG  1 
ATOM   1561 C CD1 . PHE A 1 191 ? 140.404 132.220 98.234  1.00 118.90 ?  198 PHE A CD1 1 
ATOM   1562 C CD2 . PHE A 1 191 ? 141.243 134.328 97.514  1.00 124.29 ?  198 PHE A CD2 1 
ATOM   1563 C CE1 . PHE A 1 191 ? 140.288 131.810 96.923  1.00 120.28 ?  198 PHE A CE1 1 
ATOM   1564 C CE2 . PHE A 1 191 ? 141.130 133.924 96.199  1.00 124.43 ?  198 PHE A CE2 1 
ATOM   1565 C CZ  . PHE A 1 191 ? 140.652 132.663 95.904  1.00 124.73 ?  198 PHE A CZ  1 
ATOM   1566 N N   . LEU A 1 192 ? 141.145 134.025 102.996 1.00 114.70 ?  199 LEU A N   1 
ATOM   1567 C CA  . LEU A 1 192 ? 141.991 134.025 104.191 1.00 114.22 ?  199 LEU A CA  1 
ATOM   1568 C C   . LEU A 1 192 ? 141.452 133.102 105.281 1.00 114.44 ?  199 LEU A C   1 
ATOM   1569 O O   . LEU A 1 192 ? 142.237 132.304 105.831 1.00 115.76 ?  199 LEU A O   1 
ATOM   1570 C CB  . LEU A 1 192 ? 142.200 135.463 104.678 1.00 112.45 ?  199 LEU A CB  1 
ATOM   1571 C CG  . LEU A 1 192 ? 142.519 135.678 106.155 1.00 116.03 ?  199 LEU A CG  1 
ATOM   1572 C CD1 . LEU A 1 192 ? 143.992 135.434 106.417 1.00 115.56 ?  199 LEU A CD1 1 
ATOM   1573 C CD2 . LEU A 1 192 ? 142.125 137.081 106.580 1.00 113.60 ?  199 LEU A CD2 1 
ATOM   1574 N N   . PRO A 1 193 ? 140.163 133.140 105.645 1.00 110.67 ?  200 PRO A N   1 
ATOM   1575 C CA  . PRO A 1 193 ? 139.657 132.118 106.572 1.00 109.00 ?  200 PRO A CA  1 
ATOM   1576 C C   . PRO A 1 193 ? 139.829 130.703 106.063 1.00 109.63 ?  200 PRO A C   1 
ATOM   1577 O O   . PRO A 1 193 ? 140.020 129.797 106.878 1.00 113.04 ?  200 PRO A O   1 
ATOM   1578 C CB  . PRO A 1 193 ? 138.173 132.472 106.739 1.00 110.92 ?  200 PRO A CB  1 
ATOM   1579 C CG  . PRO A 1 193 ? 137.972 133.768 106.114 1.00 110.75 ?  200 PRO A CG  1 
ATOM   1580 C CD  . PRO A 1 193 ? 139.226 134.267 105.511 1.00 112.21 ?  200 PRO A CD  1 
ATOM   1581 N N   . LEU A 1 194 ? 139.757 130.470 104.750 1.00 109.21 ?  201 LEU A N   1 
ATOM   1582 C CA  . LEU A 1 194 ? 140.017 129.124 104.246 1.00 111.12 ?  201 LEU A CA  1 
ATOM   1583 C C   . LEU A 1 194 ? 141.438 128.691 104.567 1.00 110.50 ?  201 LEU A C   1 
ATOM   1584 O O   . LEU A 1 194 ? 141.666 127.550 104.980 1.00 112.77 ?  201 LEU A O   1 
ATOM   1585 C CB  . LEU A 1 194 ? 139.776 129.049 102.742 1.00 112.66 ?  201 LEU A CB  1 
ATOM   1586 C CG  . LEU A 1 194 ? 140.270 127.772 102.068 1.00 108.26 ?  201 LEU A CG  1 
ATOM   1587 C CD1 . LEU A 1 194 ? 139.441 126.596 102.530 1.00 107.30 ?  201 LEU A CD1 1 
ATOM   1588 C CD2 . LEU A 1 194 ? 140.227 127.901 100.560 1.00 111.59 ?  201 LEU A CD2 1 
ATOM   1589 N N   . GLY A 1 195 ? 142.407 129.587 104.384 1.00 98.93  ?  202 GLY A N   1 
ATOM   1590 C CA  . GLY A 1 195 ? 143.777 129.251 104.731 1.00 99.49  ?  202 GLY A CA  1 
ATOM   1591 C C   . GLY A 1 195 ? 143.941 128.953 106.208 1.00 101.49 ?  202 GLY A C   1 
ATOM   1592 O O   . GLY A 1 195 ? 144.560 127.955 106.589 1.00 102.99 ?  202 GLY A O   1 
ATOM   1593 N N   . ILE A 1 196 ? 143.371 129.808 107.061 1.00 103.59 ?  203 ILE A N   1 
ATOM   1594 C CA  . ILE A 1 196 ? 143.485 129.586 108.501 1.00 94.10  ?  203 ILE A CA  1 
ATOM   1595 C C   . ILE A 1 196 ? 142.835 128.266 108.894 1.00 94.43  ?  203 ILE A C   1 
ATOM   1596 O O   . ILE A 1 196 ? 143.401 127.486 109.668 1.00 108.64 ?  203 ILE A O   1 
ATOM   1597 C CB  . ILE A 1 196 ? 142.875 130.763 109.281 1.00 95.27  ?  203 ILE A CB  1 
ATOM   1598 C CG1 . ILE A 1 196 ? 143.652 132.048 109.010 1.00 96.68  ?  203 ILE A CG1 1 
ATOM   1599 C CG2 . ILE A 1 196 ? 142.871 130.462 110.763 1.00 92.44  ?  203 ILE A CG2 1 
ATOM   1600 C CD1 . ILE A 1 196 ? 142.849 133.297 109.262 1.00 97.10  ?  203 ILE A CD1 1 
ATOM   1601 N N   . ILE A 1 197 ? 141.639 127.995 108.370 1.00 93.60  ?  204 ILE A N   1 
ATOM   1602 C CA  . ILE A 1 197 ? 140.912 126.784 108.730 1.00 97.08  ?  204 ILE A CA  1 
ATOM   1603 C C   . ILE A 1 197 ? 141.647 125.546 108.239 1.00 102.66 ?  204 ILE A C   1 
ATOM   1604 O O   . ILE A 1 197 ? 141.740 124.545 108.955 1.00 105.25 ?  204 ILE A O   1 
ATOM   1605 C CB  . ILE A 1 197 ? 139.475 126.847 108.185 1.00 98.86  ?  204 ILE A CB  1 
ATOM   1606 C CG1 . ILE A 1 197 ? 138.641 127.825 109.010 1.00 98.22  ?  204 ILE A CG1 1 
ATOM   1607 C CG2 . ILE A 1 197 ? 138.832 125.472 108.195 1.00 96.58  ?  204 ILE A CG2 1 
ATOM   1608 C CD1 . ILE A 1 197 ? 137.166 127.759 108.720 1.00 100.45 ?  204 ILE A CD1 1 
ATOM   1609 N N   . LEU A 1 198 ? 142.170 125.582 107.011 1.00 110.47 ?  205 LEU A N   1 
ATOM   1610 C CA  . LEU A 1 198 ? 142.913 124.438 106.498 1.00 106.73 ?  205 LEU A CA  1 
ATOM   1611 C C   . LEU A 1 198 ? 144.162 124.180 107.325 1.00 107.63 ?  205 LEU A C   1 
ATOM   1612 O O   . LEU A 1 198 ? 144.459 123.030 107.663 1.00 110.73 ?  205 LEU A O   1 
ATOM   1613 C CB  . LEU A 1 198 ? 143.280 124.657 105.032 1.00 104.56 ?  205 LEU A CB  1 
ATOM   1614 C CG  . LEU A 1 198 ? 142.164 124.459 104.007 1.00 108.41 ?  205 LEU A CG  1 
ATOM   1615 C CD1 . LEU A 1 198 ? 142.747 123.981 102.690 1.00 106.57 ?  205 LEU A CD1 1 
ATOM   1616 C CD2 . LEU A 1 198 ? 141.111 123.484 104.518 1.00 103.75 ?  205 LEU A CD2 1 
ATOM   1617 N N   . PHE A 1 199 ? 144.900 125.236 107.673 1.00 97.17  ?  206 PHE A N   1 
ATOM   1618 C CA  . PHE A 1 199 ? 146.089 125.053 108.496 1.00 97.00  ?  206 PHE A CA  1 
ATOM   1619 C C   . PHE A 1 199 ? 145.728 124.466 109.854 1.00 101.59 ?  206 PHE A C   1 
ATOM   1620 O O   . PHE A 1 199 ? 146.361 123.511 110.319 1.00 105.47 ?  206 PHE A O   1 
ATOM   1621 C CB  . PHE A 1 199 ? 146.820 126.385 108.656 1.00 98.74  ?  206 PHE A CB  1 
ATOM   1622 C CG  . PHE A 1 199 ? 147.837 126.392 109.759 1.00 107.82 ?  206 PHE A CG  1 
ATOM   1623 C CD1 . PHE A 1 199 ? 149.069 125.792 109.584 1.00 108.34 ?  206 PHE A CD1 1 
ATOM   1624 C CD2 . PHE A 1 199 ? 147.563 127.008 110.966 1.00 106.75 ?  206 PHE A CD2 1 
ATOM   1625 C CE1 . PHE A 1 199 ? 150.005 125.801 110.594 1.00 106.56 ?  206 PHE A CE1 1 
ATOM   1626 C CE2 . PHE A 1 199 ? 148.497 127.019 111.978 1.00 105.44 ?  206 PHE A CE2 1 
ATOM   1627 C CZ  . PHE A 1 199 ? 149.718 126.415 111.792 1.00 103.44 ?  206 PHE A CZ  1 
ATOM   1628 N N   . CYS A 1 200 ? 144.691 125.011 110.493 1.00 103.63 ?  207 CYS A N   1 
ATOM   1629 C CA  . CYS A 1 200 ? 144.290 124.531 111.811 1.00 97.40  ?  207 CYS A CA  1 
ATOM   1630 C C   . CYS A 1 200 ? 143.841 123.078 111.757 1.00 99.57  ?  207 CYS A C   1 
ATOM   1631 O O   . CYS A 1 200 ? 144.252 122.259 112.584 1.00 114.42 ?  207 CYS A O   1 
ATOM   1632 C CB  . CYS A 1 200 ? 143.179 125.417 112.372 1.00 97.95  ?  207 CYS A CB  1 
ATOM   1633 S SG  . CYS A 1 200 ? 143.723 127.059 112.879 1.00 115.39 ?  207 CYS A SG  1 
ATOM   1634 N N   . SER A 1 201 ? 142.998 122.736 110.783 1.00 97.48  ?  208 SER A N   1 
ATOM   1635 C CA  . SER A 1 201 ? 142.500 121.371 110.682 1.00 103.75 ?  208 SER A CA  1 
ATOM   1636 C C   . SER A 1 201 ? 143.622 120.391 110.369 1.00 104.60 ?  208 SER A C   1 
ATOM   1637 O O   . SER A 1 201 ? 143.684 119.308 110.960 1.00 109.64 ?  208 SER A O   1 
ATOM   1638 C CB  . SER A 1 201 ? 141.405 121.290 109.620 1.00 106.42 ?  208 SER A CB  1 
ATOM   1639 O OG  . SER A 1 201 ? 140.194 121.845 110.100 1.00 106.73 ?  208 SER A OG  1 
ATOM   1640 N N   . ALA A 1 202 ? 144.516 120.748 109.445 1.00 109.26 ?  209 ALA A N   1 
ATOM   1641 C CA  . ALA A 1 202 ? 145.616 119.855 109.106 1.00 108.98 ?  209 ALA A CA  1 
ATOM   1642 C C   . ALA A 1 202 ? 146.534 119.638 110.298 1.00 110.68 ?  209 ALA A C   1 
ATOM   1643 O O   . ALA A 1 202 ? 146.949 118.506 110.570 1.00 116.16 ?  209 ALA A O   1 
ATOM   1644 C CB  . ALA A 1 202 ? 146.400 120.412 107.921 1.00 109.66 ?  209 ALA A CB  1 
ATOM   1645 N N   . ARG A 1 203 ? 146.858 120.708 111.027 1.00 105.30 ?  210 ARG A N   1 
ATOM   1646 C CA  . ARG A 1 203 ? 147.706 120.557 112.202 1.00 104.20 ?  210 ARG A CA  1 
ATOM   1647 C C   . ARG A 1 203 ? 147.022 119.726 113.278 1.00 103.37 ?  210 ARG A C   1 
ATOM   1648 O O   . ARG A 1 203 ? 147.673 118.915 113.941 1.00 111.95 ?  210 ARG A O   1 
ATOM   1649 C CB  . ARG A 1 203 ? 148.101 121.926 112.743 1.00 106.20 ?  210 ARG A CB  1 
ATOM   1650 C CG  . ARG A 1 203 ? 149.155 122.618 111.903 1.00 107.34 ?  210 ARG A CG  1 
ATOM   1651 C CD  . ARG A 1 203 ? 150.556 122.336 112.418 1.00 109.46 ?  210 ARG A CD  1 
ATOM   1652 N NE  . ARG A 1 203 ? 150.944 123.259 113.477 1.00 110.49 ?  210 ARG A NE  1 
ATOM   1653 C CZ  . ARG A 1 203 ? 151.851 122.994 114.406 1.00 113.60 ?  210 ARG A CZ  1 
ATOM   1654 N NH1 . ARG A 1 203 ? 152.474 121.828 114.451 1.00 111.34 1  210 ARG A NH1 1 
ATOM   1655 N NH2 . ARG A 1 203 ? 152.140 123.922 115.313 1.00 110.44 ?  210 ARG A NH2 1 
ATOM   1656 N N   . ILE A 1 204 ? 145.713 119.902 113.464 1.00 93.10  ?  211 ILE A N   1 
ATOM   1657 C CA  . ILE A 1 204 ? 144.996 119.102 114.454 1.00 91.59  ?  211 ILE A CA  1 
ATOM   1658 C C   . ILE A 1 204 ? 145.038 117.629 114.074 1.00 98.80  ?  211 ILE A C   1 
ATOM   1659 O O   . ILE A 1 204 ? 145.311 116.762 114.913 1.00 112.13 ?  211 ILE A O   1 
ATOM   1660 C CB  . ILE A 1 204 ? 143.548 119.596 114.605 1.00 92.23  ?  211 ILE A CB  1 
ATOM   1661 C CG1 . ILE A 1 204 ? 143.503 120.920 115.359 1.00 93.52  ?  211 ILE A CG1 1 
ATOM   1662 C CG2 . ILE A 1 204 ? 142.727 118.566 115.349 1.00 91.18  ?  211 ILE A CG2 1 
ATOM   1663 C CD1 . ILE A 1 204 ? 142.134 121.540 115.377 1.00 93.93  ?  211 ILE A CD1 1 
ATOM   1664 N N   . ILE A 1 205 ? 144.766 117.322 112.803 1.00 114.70 ?  212 ILE A N   1 
ATOM   1665 C CA  . ILE A 1 205 ? 144.774 115.928 112.367 1.00 116.00 ?  212 ILE A CA  1 
ATOM   1666 C C   . ILE A 1 205 ? 146.162 115.332 112.540 1.00 117.06 ?  212 ILE A C   1 
ATOM   1667 O O   . ILE A 1 205 ? 146.315 114.215 113.049 1.00 119.34 ?  212 ILE A O   1 
ATOM   1668 C CB  . ILE A 1 205 ? 144.302 115.800 110.906 1.00 119.56 ?  212 ILE A CB  1 
ATOM   1669 C CG1 . ILE A 1 205 ? 142.906 116.392 110.687 1.00 120.19 ?  212 ILE A CG1 1 
ATOM   1670 C CG2 . ILE A 1 205 ? 144.294 114.341 110.485 1.00 118.20 ?  212 ILE A CG2 1 
ATOM   1671 C CD1 . ILE A 1 205 ? 141.930 116.194 111.814 1.00 118.87 ?  212 ILE A CD1 1 
ATOM   1672 N N   . TRP A 1 206 ? 147.196 116.068 112.126 1.00 121.18 ?  213 TRP A N   1 
ATOM   1673 C CA  . TRP A 1 206 ? 148.557 115.555 112.219 1.00 122.14 ?  213 TRP A CA  1 
ATOM   1674 C C   . TRP A 1 206 ? 148.977 115.343 113.666 1.00 126.85 ?  213 TRP A C   1 
ATOM   1675 O O   . TRP A 1 206 ? 149.625 114.342 113.987 1.00 132.36 ?  213 TRP A O   1 
ATOM   1676 C CB  . TRP A 1 206 ? 149.522 116.504 111.510 1.00 125.76 ?  213 TRP A CB  1 
ATOM   1677 C CG  . TRP A 1 206 ? 150.936 116.019 111.501 1.00 131.06 ?  213 TRP A CG  1 
ATOM   1678 C CD1 . TRP A 1 206 ? 151.443 114.986 110.770 1.00 128.97 ?  213 TRP A CD1 1 
ATOM   1679 C CD2 . TRP A 1 206 ? 152.033 116.561 112.243 1.00 133.21 ?  213 TRP A CD2 1 
ATOM   1680 N NE1 . TRP A 1 206 ? 152.785 114.842 111.021 1.00 129.58 ?  213 TRP A NE1 1 
ATOM   1681 C CE2 . TRP A 1 206 ? 153.172 115.799 111.921 1.00 132.88 ?  213 TRP A CE2 1 
ATOM   1682 C CE3 . TRP A 1 206 ? 152.162 117.615 113.153 1.00 129.32 ?  213 TRP A CE3 1 
ATOM   1683 C CZ2 . TRP A 1 206 ? 154.423 116.057 112.476 1.00 130.83 ?  213 TRP A CZ2 1 
ATOM   1684 C CZ3 . TRP A 1 206 ? 153.404 117.869 113.702 1.00 130.24 ?  213 TRP A CZ3 1 
ATOM   1685 C CH2 . TRP A 1 206 ? 154.519 117.094 113.362 1.00 129.84 ?  213 TRP A CH2 1 
ATOM   1686 N N   . SER A 1 207 ? 148.625 116.274 114.556 1.00 115.88 ?  214 SER A N   1 
ATOM   1687 C CA  . SER A 1 207 ? 148.997 116.126 115.958 1.00 109.05 ?  214 SER A CA  1 
ATOM   1688 C C   . SER A 1 207 ? 148.265 114.962 116.609 1.00 108.25 ?  214 SER A C   1 
ATOM   1689 O O   . SER A 1 207 ? 148.866 114.197 117.369 1.00 115.20 ?  214 SER A O   1 
ATOM   1690 C CB  . SER A 1 207 ? 148.726 117.424 116.714 1.00 110.17 ?  214 SER A CB  1 
ATOM   1691 O OG  . SER A 1 207 ? 149.580 118.456 116.257 1.00 117.47 ?  214 SER A OG  1 
ATOM   1692 N N   . LEU A 1 208 ? 146.970 114.805 116.326 1.00 107.57 ?  215 LEU A N   1 
ATOM   1693 C CA  . LEU A 1 208 ? 146.234 113.697 116.923 1.00 109.92 ?  215 LEU A CA  1 
ATOM   1694 C C   . LEU A 1 208 ? 146.675 112.356 116.353 1.00 121.76 ?  215 LEU A C   1 
ATOM   1695 O O   . LEU A 1 208 ? 146.587 111.334 117.042 1.00 125.53 ?  215 LEU A O   1 
ATOM   1696 C CB  . LEU A 1 208 ? 144.733 113.890 116.728 1.00 110.75 ?  215 LEU A CB  1 
ATOM   1697 C CG  . LEU A 1 208 ? 144.047 114.785 117.759 1.00 113.89 ?  215 LEU A CG  1 
ATOM   1698 C CD1 . LEU A 1 208 ? 142.548 114.560 117.753 1.00 112.44 ?  215 LEU A CD1 1 
ATOM   1699 C CD2 . LEU A 1 208 ? 144.619 114.540 119.140 1.00 118.21 ?  215 LEU A CD2 1 
ATOM   1700 N N   . ARG A 1 209 ? 147.143 112.330 115.104 1.00 134.54 ?  216 ARG A N   1 
ATOM   1701 C CA  . ARG A 1 209 ? 147.659 111.087 114.545 1.00 131.89 ?  216 ARG A CA  1 
ATOM   1702 C C   . ARG A 1 209 ? 149.040 110.756 115.095 1.00 130.33 ?  216 ARG A C   1 
ATOM   1703 O O   . ARG A 1 209 ? 149.339 109.590 115.369 1.00 129.52 ?  216 ARG A O   1 
ATOM   1704 C CB  . ARG A 1 209 ? 147.700 111.174 113.020 1.00 130.12 ?  216 ARG A CB  1 
ATOM   1705 C CG  . ARG A 1 209 ? 146.636 110.341 112.333 1.00 131.35 ?  216 ARG A CG  1 
ATOM   1706 C CD  . ARG A 1 209 ? 145.290 111.044 112.352 1.00 134.04 ?  216 ARG A CD  1 
ATOM   1707 N NE  . ARG A 1 209 ? 144.262 110.283 111.653 1.00 136.06 ?  216 ARG A NE  1 
ATOM   1708 C CZ  . ARG A 1 209 ? 144.198 110.136 110.337 1.00 134.15 ?  216 ARG A CZ  1 
ATOM   1709 N NH1 . ARG A 1 209 ? 145.088 110.696 109.534 1.00 130.36 1  216 ARG A NH1 1 
ATOM   1710 N NH2 . ARG A 1 209 ? 143.214 109.411 109.813 1.00 132.38 ?  216 ARG A NH2 1 
ATOM   1711 N N   . GLN A 1 210 ? 149.889 111.771 115.264 1.00 128.63 ?  217 GLN A N   1 
ATOM   1712 C CA  . GLN A 1 210 ? 151.249 111.540 115.732 1.00 128.03 ?  217 GLN A CA  1 
ATOM   1713 C C   . GLN A 1 210 ? 151.278 111.093 117.188 1.00 128.37 ?  217 GLN A C   1 
ATOM   1714 O O   . GLN A 1 210 ? 152.195 110.371 117.594 1.00 128.44 ?  217 GLN A O   1 
ATOM   1715 C CB  . GLN A 1 210 ? 152.081 112.807 115.537 1.00 126.15 ?  217 GLN A CB  1 
ATOM   1716 C CG  . GLN A 1 210 ? 153.540 112.670 115.919 1.00 127.45 ?  217 GLN A CG  1 
ATOM   1717 C CD  . GLN A 1 210 ? 153.851 113.333 117.241 1.00 131.54 ?  217 GLN A CD  1 
ATOM   1718 O OE1 . GLN A 1 210 ? 152.952 113.609 118.034 1.00 130.74 ?  217 GLN A OE1 1 
ATOM   1719 N NE2 . GLN A 1 210 ? 155.129 113.592 117.488 1.00 130.43 ?  217 GLN A NE2 1 
ATOM   1720 N N   . ARG A 1 211 ? 150.292 111.497 117.982 1.00 123.57 ?  218 ARG A N   1 
ATOM   1721 C CA  . ARG A 1 211 ? 150.223 111.110 119.383 1.00 124.44 ?  218 ARG A CA  1 
ATOM   1722 C C   . ARG A 1 211 ? 149.438 109.823 119.596 1.00 123.58 ?  218 ARG A C   1 
ATOM   1723 O O   . ARG A 1 211 ? 149.189 109.446 120.745 1.00 126.27 ?  218 ARG A O   1 
ATOM   1724 C CB  . ARG A 1 211 ? 149.626 112.247 120.215 1.00 124.47 ?  218 ARG A CB  1 
ATOM   1725 C CG  . ARG A 1 211 ? 150.542 113.460 120.312 1.00 123.12 ?  218 ARG A CG  1 
ATOM   1726 C CD  . ARG A 1 211 ? 150.002 114.513 121.260 1.00 120.45 ?  218 ARG A CD  1 
ATOM   1727 N NE  . ARG A 1 211 ? 151.004 114.935 122.231 1.00 125.33 ?  218 ARG A NE  1 
ATOM   1728 C CZ  . ARG A 1 211 ? 151.212 114.342 123.398 1.00 128.72 ?  218 ARG A CZ  1 
ATOM   1729 N NH1 . ARG A 1 211 ? 150.498 113.296 123.778 1.00 123.58 1  218 ARG A NH1 1 
ATOM   1730 N NH2 . ARG A 1 211 ? 152.162 114.808 124.203 1.00 127.42 ?  218 ARG A NH2 1 
ATOM   1731 N N   . GLN A 1 212 ? 149.043 109.152 118.514 1.00 131.77 ?  219 GLN A N   1 
ATOM   1732 C CA  . GLN A 1 212 ? 148.441 107.819 118.571 1.00 136.27 ?  219 GLN A CA  1 
ATOM   1733 C C   . GLN A 1 212 ? 147.158 107.798 119.397 1.00 134.51 ?  219 GLN A C   1 
ATOM   1734 O O   . GLN A 1 212 ? 146.859 106.818 120.082 1.00 132.88 ?  219 GLN A O   1 
ATOM   1735 C CB  . GLN A 1 212 ? 149.438 106.785 119.103 1.00 135.20 ?  219 GLN A CB  1 
ATOM   1736 C CG  . GLN A 1 212 ? 150.466 106.316 118.087 1.00 133.94 ?  219 GLN A CG  1 
ATOM   1737 C CD  . GLN A 1 212 ? 151.598 107.304 117.901 1.00 135.61 ?  219 GLN A CD  1 
ATOM   1738 O OE1 . GLN A 1 212 ? 152.162 107.807 118.871 1.00 135.11 ?  219 GLN A OE1 1 
ATOM   1739 N NE2 . GLN A 1 212 ? 151.941 107.582 116.649 1.00 133.83 ?  219 GLN A NE2 1 
ATOM   1740 N N   . MET A 1 213 ? 146.388 108.878 119.337 1.00 126.70 ?  220 MET A N   1 
ATOM   1741 C CA  . MET A 1 213 ? 145.066 108.878 119.948 1.00 130.04 ?  220 MET A CA  1 
ATOM   1742 C C   . MET A 1 213 ? 143.963 108.489 118.975 1.00 135.00 ?  220 MET A C   1 
ATOM   1743 O O   . MET A 1 213 ? 142.797 108.440 119.377 1.00 131.47 ?  220 MET A O   1 
ATOM   1744 C CB  . MET A 1 213 ? 144.746 110.241 120.562 1.00 127.20 ?  220 MET A CB  1 
ATOM   1745 C CG  . MET A 1 213 ? 145.911 110.925 121.231 1.00 124.88 ?  220 MET A CG  1 
ATOM   1746 S SD  . MET A 1 213 ? 145.342 112.386 122.109 1.00 129.17 ?  220 MET A SD  1 
ATOM   1747 C CE  . MET A 1 213 ? 146.833 113.358 122.136 1.00 125.34 ?  220 MET A CE  1 
ATOM   1748 N N   . ASP A 1 214 ? 144.301 108.201 117.716 1.00 145.59 ?  221 ASP A N   1 
ATOM   1749 C CA  . ASP A 1 214 ? 143.295 107.766 116.756 1.00 143.17 ?  221 ASP A CA  1 
ATOM   1750 C C   . ASP A 1 214 ? 142.602 106.484 117.192 1.00 143.36 ?  221 ASP A C   1 
ATOM   1751 O O   . ASP A 1 214 ? 141.458 106.244 116.794 1.00 142.81 ?  221 ASP A O   1 
ATOM   1752 C CB  . ASP A 1 214 ? 143.932 107.566 115.382 1.00 142.41 ?  221 ASP A CB  1 
ATOM   1753 C CG  . ASP A 1 214 ? 145.059 108.540 115.119 1.00 142.41 ?  221 ASP A CG  1 
ATOM   1754 O OD1 . ASP A 1 214 ? 144.885 109.740 115.412 1.00 140.77 ?  221 ASP A OD1 1 
ATOM   1755 O OD2 . ASP A 1 214 ? 146.118 108.104 114.622 1.00 142.02 -1 221 ASP A OD2 1 
ATOM   1756 N N   . ARG A 1 215 ? 143.263 105.662 118.007 1.00 146.75 ?  222 ARG A N   1 
ATOM   1757 C CA  . ARG A 1 215 ? 142.663 104.439 118.536 1.00 147.93 ?  222 ARG A CA  1 
ATOM   1758 C C   . ARG A 1 215 ? 141.656 104.783 119.636 1.00 149.87 ?  222 ARG A C   1 
ATOM   1759 O O   . ARG A 1 215 ? 141.820 104.449 120.809 1.00 149.27 ?  222 ARG A O   1 
ATOM   1760 C CB  . ARG A 1 215 ? 143.749 103.503 119.049 1.00 147.28 ?  222 ARG A CB  1 
ATOM   1761 C CG  . ARG A 1 215 ? 144.919 104.226 119.691 1.00 148.23 ?  222 ARG A CG  1 
ATOM   1762 C CD  . ARG A 1 215 ? 145.476 103.448 120.869 1.00 150.27 ?  222 ARG A CD  1 
ATOM   1763 N NE  . ARG A 1 215 ? 146.235 104.306 121.771 1.00 152.12 ?  222 ARG A NE  1 
ATOM   1764 C CZ  . ARG A 1 215 ? 145.715 104.944 122.811 1.00 150.33 ?  222 ARG A CZ  1 
ATOM   1765 N NH1 . ARG A 1 215 ? 144.434 104.832 123.119 1.00 148.22 1  222 ARG A NH1 1 
ATOM   1766 N NH2 . ARG A 1 215 ? 146.501 105.713 123.559 1.00 146.51 ?  222 ARG A NH2 1 
ATOM   1767 N N   . HIS A 1 216 ? 140.591 105.469 119.223 1.00 147.98 ?  223 HIS A N   1 
ATOM   1768 C CA  . HIS A 1 216 ? 139.540 105.897 120.137 1.00 144.99 ?  223 HIS A CA  1 
ATOM   1769 C C   . HIS A 1 216 ? 138.321 106.327 119.332 1.00 145.66 ?  223 HIS A C   1 
ATOM   1770 O O   . HIS A 1 216 ? 138.449 107.072 118.355 1.00 147.28 ?  223 HIS A O   1 
ATOM   1771 C CB  . HIS A 1 216 ? 140.039 107.036 121.032 1.00 144.87 ?  223 HIS A CB  1 
ATOM   1772 C CG  . HIS A 1 216 ? 139.168 107.308 122.220 1.00 148.56 ?  223 HIS A CG  1 
ATOM   1773 N ND1 . HIS A 1 216 ? 137.813 107.061 122.229 1.00 147.36 ?  223 HIS A ND1 1 
ATOM   1774 C CD2 . HIS A 1 216 ? 139.466 107.805 123.444 1.00 147.87 ?  223 HIS A CD2 1 
ATOM   1775 C CE1 . HIS A 1 216 ? 137.312 107.397 123.404 1.00 146.42 ?  223 HIS A CE1 1 
ATOM   1776 N NE2 . HIS A 1 216 ? 138.295 107.851 124.160 1.00 147.77 ?  223 HIS A NE2 1 
ATOM   1777 N N   . ALA A 1 217 ? 137.138 105.851 119.725 1.00 145.59 ?  224 ALA A N   1 
ATOM   1778 C CA  . ALA A 1 217 ? 135.923 106.198 118.996 1.00 147.05 ?  224 ALA A CA  1 
ATOM   1779 C C   . ALA A 1 217 ? 135.642 107.693 119.062 1.00 147.75 ?  224 ALA A C   1 
ATOM   1780 O O   . ALA A 1 217 ? 135.270 108.306 118.055 1.00 145.15 ?  224 ALA A O   1 
ATOM   1781 C CB  . ALA A 1 217 ? 134.738 105.403 119.545 1.00 144.39 ?  224 ALA A CB  1 
ATOM   1782 N N   . LYS A 1 218 ? 135.813 108.300 120.239 1.00 144.68 ?  225 LYS A N   1 
ATOM   1783 C CA  . LYS A 1 218 ? 135.535 109.726 120.379 1.00 142.69 ?  225 LYS A CA  1 
ATOM   1784 C C   . LYS A 1 218 ? 136.549 110.572 119.618 1.00 142.09 ?  225 LYS A C   1 
ATOM   1785 O O   . LYS A 1 218 ? 136.184 111.577 118.999 1.00 143.65 ?  225 LYS A O   1 
ATOM   1786 C CB  . LYS A 1 218 ? 135.506 110.111 121.857 1.00 140.53 ?  225 LYS A CB  1 
ATOM   1787 C CG  . LYS A 1 218 ? 134.420 109.404 122.648 1.00 140.46 ?  225 LYS A CG  1 
ATOM   1788 C CD  . LYS A 1 218 ? 134.438 109.819 124.106 1.00 142.98 ?  225 LYS A CD  1 
ATOM   1789 C CE  . LYS A 1 218 ? 133.034 110.096 124.618 1.00 143.25 ?  225 LYS A CE  1 
ATOM   1790 N NZ  . LYS A 1 218 ? 132.119 110.532 123.526 1.00 143.20 1  225 LYS A NZ  1 
ATOM   1791 N N   . ILE A 1 219 ? 137.825 110.183 119.647 1.00 137.15 ?  226 ILE A N   1 
ATOM   1792 C CA  . ILE A 1 219 ? 138.831 110.917 118.886 1.00 139.76 ?  226 ILE A CA  1 
ATOM   1793 C C   . ILE A 1 219 ? 138.562 110.793 117.393 1.00 142.74 ?  226 ILE A C   1 
ATOM   1794 O O   . ILE A 1 219 ? 138.704 111.763 116.641 1.00 143.06 ?  226 ILE A O   1 
ATOM   1795 C CB  . ILE A 1 219 ? 140.247 110.434 119.249 1.00 141.13 ?  226 ILE A CB  1 
ATOM   1796 C CG1 . ILE A 1 219 ? 140.634 110.922 120.645 1.00 140.28 ?  226 ILE A CG1 1 
ATOM   1797 C CG2 . ILE A 1 219 ? 141.259 110.924 118.224 1.00 138.64 ?  226 ILE A CG2 1 
ATOM   1798 C CD1 . ILE A 1 219 ? 140.929 112.400 120.712 1.00 137.78 ?  226 ILE A CD1 1 
ATOM   1799 N N   . LYS A 1 220 ? 138.170 109.601 116.938 1.00 145.36 ?  227 LYS A N   1 
ATOM   1800 C CA  . LYS A 1 220 ? 137.841 109.426 115.526 1.00 144.47 ?  227 LYS A CA  1 
ATOM   1801 C C   . LYS A 1 220 ? 136.623 110.255 115.135 1.00 141.12 ?  227 LYS A C   1 
ATOM   1802 O O   . LYS A 1 220 ? 136.580 110.832 114.041 1.00 139.36 ?  227 LYS A O   1 
ATOM   1803 C CB  . LYS A 1 220 ? 137.611 107.947 115.219 1.00 142.84 ?  227 LYS A CB  1 
ATOM   1804 C CG  . LYS A 1 220 ? 138.835 107.234 114.672 1.00 141.57 ?  227 LYS A CG  1 
ATOM   1805 C CD  . LYS A 1 220 ? 139.572 108.105 113.664 1.00 142.43 ?  227 LYS A CD  1 
ATOM   1806 C CE  . LYS A 1 220 ? 140.656 107.324 112.940 1.00 142.16 ?  227 LYS A CE  1 
ATOM   1807 N NZ  . LYS A 1 220 ? 141.909 108.115 112.798 1.00 141.75 1  227 LYS A NZ  1 
ATOM   1808 N N   . ARG A 1 221 ? 135.623 110.326 116.016 1.00 140.21 ?  228 ARG A N   1 
ATOM   1809 C CA  . ARG A 1 221 ? 134.469 111.179 115.755 1.00 143.51 ?  228 ARG A CA  1 
ATOM   1810 C C   . ARG A 1 221 ? 134.878 112.643 115.658 1.00 147.04 ?  228 ARG A C   1 
ATOM   1811 O O   . ARG A 1 221 ? 134.394 113.374 114.787 1.00 144.75 ?  228 ARG A O   1 
ATOM   1812 C CB  . ARG A 1 221 ? 133.418 110.991 116.848 1.00 142.10 ?  228 ARG A CB  1 
ATOM   1813 C CG  . ARG A 1 221 ? 132.018 110.742 116.320 1.00 141.68 ?  228 ARG A CG  1 
ATOM   1814 C CD  . ARG A 1 221 ? 130.986 110.891 117.422 1.00 143.11 ?  228 ARG A CD  1 
ATOM   1815 N NE  . ARG A 1 221 ? 130.498 112.261 117.525 1.00 145.35 ?  228 ARG A NE  1 
ATOM   1816 C CZ  . ARG A 1 221 ? 129.859 112.753 118.578 1.00 146.17 ?  228 ARG A CZ  1 
ATOM   1817 N NH1 . ARG A 1 221 ? 129.611 112.011 119.645 1.00 144.73 1  228 ARG A NH1 1 
ATOM   1818 N NH2 . ARG A 1 221 ? 129.460 114.021 118.561 1.00 142.52 ?  228 ARG A NH2 1 
ATOM   1819 N N   . ALA A 1 222 ? 135.770 113.087 116.547 1.00 141.58 ?  229 ALA A N   1 
ATOM   1820 C CA  . ALA A 1 222 ? 136.264 114.460 116.482 1.00 135.63 ?  229 ALA A CA  1 
ATOM   1821 C C   . ALA A 1 222 ? 137.016 114.714 115.184 1.00 133.28 ?  229 ALA A C   1 
ATOM   1822 O O   . ALA A 1 222 ? 136.875 115.779 114.573 1.00 141.47 ?  229 ALA A O   1 
ATOM   1823 C CB  . ALA A 1 222 ? 137.159 114.752 117.684 1.00 133.79 ?  229 ALA A CB  1 
ATOM   1824 N N   . ILE A 1 223 ? 137.825 113.745 114.753 1.00 126.31 ?  230 ILE A N   1 
ATOM   1825 C CA  . ILE A 1 223 ? 138.574 113.887 113.509 1.00 133.15 ?  230 ILE A CA  1 
ATOM   1826 C C   . ILE A 1 223 ? 137.611 114.037 112.340 1.00 138.33 ?  230 ILE A C   1 
ATOM   1827 O O   . ILE A 1 223 ? 137.765 114.922 111.483 1.00 136.80 ?  230 ILE A O   1 
ATOM   1828 C CB  . ILE A 1 223 ? 139.494 112.668 113.310 1.00 132.48 ?  230 ILE A CB  1 
ATOM   1829 C CG1 . ILE A 1 223 ? 140.619 112.653 114.344 1.00 135.02 ?  230 ILE A CG1 1 
ATOM   1830 C CG2 . ILE A 1 223 ? 140.088 112.679 111.914 1.00 133.99 ?  230 ILE A CG2 1 
ATOM   1831 C CD1 . ILE A 1 223 ? 141.699 113.666 114.114 1.00 136.81 ?  230 ILE A CD1 1 
ATOM   1832 N N   . THR A 1 224 ? 136.595 113.172 112.298 1.00 145.25 ?  231 THR A N   1 
ATOM   1833 C CA  . THR A 1 224 ? 135.605 113.215 111.230 1.00 144.10 ?  231 THR A CA  1 
ATOM   1834 C C   . THR A 1 224 ? 134.858 114.541 111.233 1.00 142.36 ?  231 THR A C   1 
ATOM   1835 O O   . THR A 1 224 ? 134.625 115.134 110.176 1.00 143.48 ?  231 THR A O   1 
ATOM   1836 C CB  . THR A 1 224 ? 134.634 112.040 111.379 1.00 144.22 ?  231 THR A CB  1 
ATOM   1837 O OG1 . THR A 1 224 ? 135.226 110.855 110.832 1.00 143.64 ?  231 THR A OG1 1 
ATOM   1838 C CG2 . THR A 1 224 ? 133.321 112.322 110.665 1.00 141.64 ?  231 THR A CG2 1 
ATOM   1839 N N   . PHE A 1 225 ? 134.486 115.030 112.417 1.00 134.02 ?  232 PHE A N   1 
ATOM   1840 C CA  . PHE A 1 225 ? 133.739 116.280 112.489 1.00 132.51 ?  232 PHE A CA  1 
ATOM   1841 C C   . PHE A 1 225 ? 134.587 117.475 112.080 1.00 129.98 ?  232 PHE A C   1 
ATOM   1842 O O   . PHE A 1 225 ? 134.076 118.395 111.437 1.00 134.15 ?  232 PHE A O   1 
ATOM   1843 C CB  . PHE A 1 225 ? 133.177 116.481 113.892 1.00 133.70 ?  232 PHE A CB  1 
ATOM   1844 C CG  . PHE A 1 225 ? 131.897 115.743 114.133 1.00 138.84 ?  232 PHE A CG  1 
ATOM   1845 C CD1 . PHE A 1 225 ? 131.285 115.046 113.105 1.00 138.06 ?  232 PHE A CD1 1 
ATOM   1846 C CD2 . PHE A 1 225 ? 131.306 115.741 115.381 1.00 139.56 ?  232 PHE A CD2 1 
ATOM   1847 C CE1 . PHE A 1 225 ? 130.109 114.363 113.318 1.00 137.65 ?  232 PHE A CE1 1 
ATOM   1848 C CE2 . PHE A 1 225 ? 130.131 115.058 115.599 1.00 140.49 ?  232 PHE A CE2 1 
ATOM   1849 C CZ  . PHE A 1 225 ? 129.532 114.367 114.566 1.00 138.88 ?  232 PHE A CZ  1 
ATOM   1850 N N   . ILE A 1 226 ? 135.872 117.487 112.431 1.00 116.46 ?  233 ILE A N   1 
ATOM   1851 C CA  . ILE A 1 226 ? 136.744 118.576 112.003 1.00 117.61 ?  233 ILE A CA  1 
ATOM   1852 C C   . ILE A 1 226 ? 136.896 118.570 110.486 1.00 120.46 ?  233 ILE A C   1 
ATOM   1853 O O   . ILE A 1 226 ? 136.786 119.615 109.822 1.00 125.80 ?  233 ILE A O   1 
ATOM   1854 C CB  . ILE A 1 226 ? 138.103 118.475 112.716 1.00 116.59 ?  233 ILE A CB  1 
ATOM   1855 C CG1 . ILE A 1 226 ? 137.964 118.963 114.156 1.00 117.03 ?  233 ILE A CG1 1 
ATOM   1856 C CG2 . ILE A 1 226 ? 139.170 119.260 111.975 1.00 115.30 ?  233 ILE A CG2 1 
ATOM   1857 C CD1 . ILE A 1 226 ? 139.253 119.000 114.911 1.00 117.45 ?  233 ILE A CD1 1 
ATOM   1858 N N   . MET A 1 227 ? 137.128 117.388 109.910 1.00 125.18 ?  234 MET A N   1 
ATOM   1859 C CA  . MET A 1 227 ? 137.249 117.302 108.460 1.00 126.72 ?  234 MET A CA  1 
ATOM   1860 C C   . MET A 1 227 ? 135.952 117.714 107.775 1.00 126.69 ?  234 MET A C   1 
ATOM   1861 O O   . MET A 1 227 ? 135.974 118.418 106.759 1.00 125.05 ?  234 MET A O   1 
ATOM   1862 C CB  . MET A 1 227 ? 137.654 115.889 108.045 1.00 128.91 ?  234 MET A CB  1 
ATOM   1863 C CG  . MET A 1 227 ? 138.372 115.749 106.689 1.00 130.54 ?  234 MET A CG  1 
ATOM   1864 S SD  . MET A 1 227 ? 139.953 116.602 106.424 1.00 137.96 ?  234 MET A SD  1 
ATOM   1865 C CE  . MET A 1 227 ? 139.498 118.321 106.180 1.00 124.13 ?  234 MET A CE  1 
ATOM   1866 N N   . VAL A 1 228 ? 134.810 117.297 108.325 1.00 126.08 ?  235 VAL A N   1 
ATOM   1867 C CA  . VAL A 1 228 ? 133.529 117.634 107.719 1.00 124.00 ?  235 VAL A CA  1 
ATOM   1868 C C   . VAL A 1 228 ? 133.233 119.120 107.865 1.00 125.15 ?  235 VAL A C   1 
ATOM   1869 O O   . VAL A 1 228 ? 132.604 119.713 106.988 1.00 129.21 ?  235 VAL A O   1 
ATOM   1870 C CB  . VAL A 1 228 ? 132.406 116.754 108.307 1.00 128.40 ?  235 VAL A CB  1 
ATOM   1871 C CG1 . VAL A 1 228 ? 131.715 117.433 109.473 1.00 124.30 ?  235 VAL A CG1 1 
ATOM   1872 C CG2 . VAL A 1 228 ? 131.400 116.392 107.228 1.00 128.91 ?  235 VAL A CG2 1 
ATOM   1873 N N   . VAL A 1 229 ? 133.686 119.752 108.949 1.00 119.05 ?  236 VAL A N   1 
ATOM   1874 C CA  . VAL A 1 229 ? 133.501 121.192 109.099 1.00 115.02 ?  236 VAL A CA  1 
ATOM   1875 C C   . VAL A 1 229 ? 134.282 121.935 108.026 1.00 110.92 ?  236 VAL A C   1 
ATOM   1876 O O   . VAL A 1 229 ? 133.757 122.841 107.362 1.00 116.79 ?  236 VAL A O   1 
ATOM   1877 C CB  . VAL A 1 229 ? 133.914 121.640 110.511 1.00 115.61 ?  236 VAL A CB  1 
ATOM   1878 C CG1 . VAL A 1 229 ? 134.421 123.069 110.490 1.00 115.41 ?  236 VAL A CG1 1 
ATOM   1879 C CG2 . VAL A 1 229 ? 132.749 121.498 111.471 1.00 113.53 ?  236 VAL A CG2 1 
ATOM   1880 N N   . ALA A 1 230 ? 135.543 121.548 107.823 1.00 111.17 ?  237 ALA A N   1 
ATOM   1881 C CA  . ALA A 1 230 ? 136.326 122.182 106.767 1.00 112.62 ?  237 ALA A CA  1 
ATOM   1882 C C   . ALA A 1 230 ? 135.694 121.949 105.399 1.00 116.60 ?  237 ALA A C   1 
ATOM   1883 O O   . ALA A 1 230 ? 135.586 122.878 104.585 1.00 124.15 ?  237 ALA A O   1 
ATOM   1884 C CB  . ALA A 1 230 ? 137.763 121.666 106.792 1.00 118.16 ?  237 ALA A CB  1 
ATOM   1885 N N   . ILE A 1 231 ? 135.250 120.718 105.138 1.00 124.73 ?  238 ILE A N   1 
ATOM   1886 C CA  . ILE A 1 231 ? 134.671 120.387 103.840 1.00 127.77 ?  238 ILE A CA  1 
ATOM   1887 C C   . ILE A 1 231 ? 133.395 121.183 103.602 1.00 122.70 ?  238 ILE A C   1 
ATOM   1888 O O   . ILE A 1 231 ? 133.167 121.697 102.502 1.00 121.05 ?  238 ILE A O   1 
ATOM   1889 C CB  . ILE A 1 231 ? 134.426 118.869 103.740 1.00 127.80 ?  238 ILE A CB  1 
ATOM   1890 C CG1 . ILE A 1 231 ? 135.718 118.147 103.350 1.00 124.46 ?  238 ILE A CG1 1 
ATOM   1891 C CG2 . ILE A 1 231 ? 133.323 118.559 102.740 1.00 124.58 ?  238 ILE A CG2 1 
ATOM   1892 C CD1 . ILE A 1 231 ? 136.366 118.688 102.097 1.00 118.73 ?  238 ILE A CD1 1 
ATOM   1893 N N   . VAL A 1 232 ? 132.542 121.295 104.623 1.00 114.41 ?  239 VAL A N   1 
ATOM   1894 C CA  . VAL A 1 232 ? 131.302 122.051 104.489 1.00 116.96 ?  239 VAL A CA  1 
ATOM   1895 C C   . VAL A 1 232 ? 131.597 123.520 104.225 1.00 117.06 ?  239 VAL A C   1 
ATOM   1896 O O   . VAL A 1 232 ? 130.944 124.154 103.388 1.00 119.91 ?  239 VAL A O   1 
ATOM   1897 C CB  . VAL A 1 232 ? 130.420 121.862 105.737 1.00 114.99 ?  239 VAL A CB  1 
ATOM   1898 C CG1 . VAL A 1 232 ? 129.306 122.893 105.766 1.00 110.72 ?  239 VAL A CG1 1 
ATOM   1899 C CG2 . VAL A 1 232 ? 129.832 120.466 105.752 1.00 115.99 ?  239 VAL A CG2 1 
ATOM   1900 N N   . PHE A 1 233 ? 132.577 124.088 104.931 1.00 110.81 ?  240 PHE A N   1 
ATOM   1901 C CA  . PHE A 1 233 ? 132.930 125.482 104.683 1.00 106.85 ?  240 PHE A CA  1 
ATOM   1902 C C   . PHE A 1 233 ? 133.349 125.690 103.232 1.00 109.24 ?  240 PHE A C   1 
ATOM   1903 O O   . PHE A 1 233 ? 132.858 126.605 102.555 1.00 115.32 ?  240 PHE A O   1 
ATOM   1904 C CB  . PHE A 1 233 ? 134.043 125.920 105.632 1.00 110.63 ?  240 PHE A CB  1 
ATOM   1905 C CG  . PHE A 1 233 ? 134.551 127.308 105.374 1.00 110.74 ?  240 PHE A CG  1 
ATOM   1906 C CD1 . PHE A 1 233 ? 133.927 128.403 105.939 1.00 112.66 ?  240 PHE A CD1 1 
ATOM   1907 C CD2 . PHE A 1 233 ? 135.658 127.518 104.571 1.00 111.69 ?  240 PHE A CD2 1 
ATOM   1908 C CE1 . PHE A 1 233 ? 134.395 129.677 105.706 1.00 112.08 ?  240 PHE A CE1 1 
ATOM   1909 C CE2 . PHE A 1 233 ? 136.127 128.792 104.334 1.00 111.73 ?  240 PHE A CE2 1 
ATOM   1910 C CZ  . PHE A 1 233 ? 135.495 129.870 104.902 1.00 109.50 ?  240 PHE A CZ  1 
ATOM   1911 N N   . VAL A 1 234 ? 134.251 124.839 102.731 1.00 118.80 ?  241 VAL A N   1 
ATOM   1912 C CA  . VAL A 1 234 ? 134.713 125.004 101.353 1.00 120.81 ?  241 VAL A CA  1 
ATOM   1913 C C   . VAL A 1 234 ? 133.565 124.808 100.370 1.00 120.54 ?  241 VAL A C   1 
ATOM   1914 O O   . VAL A 1 234 ? 133.409 125.580 99.419  1.00 118.52 ?  241 VAL A O   1 
ATOM   1915 C CB  . VAL A 1 234 ? 135.888 124.060 101.043 1.00 119.58 ?  241 VAL A CB  1 
ATOM   1916 C CG1 . VAL A 1 234 ? 136.568 124.490 99.758  1.00 119.64 ?  241 VAL A CG1 1 
ATOM   1917 C CG2 . VAL A 1 234 ? 136.896 124.093 102.163 1.00 119.66 ?  241 VAL A CG2 1 
ATOM   1918 N N   . ILE A 1 235 ? 132.734 123.788 100.592 1.00 127.01 ?  242 ILE A N   1 
ATOM   1919 C CA  . ILE A 1 235 ? 131.642 123.498 99.666  1.00 126.40 ?  242 ILE A CA  1 
ATOM   1920 C C   . ILE A 1 235 ? 130.658 124.658 99.616  1.00 128.02 ?  242 ILE A C   1 
ATOM   1921 O O   . ILE A 1 235 ? 130.181 125.040 98.541  1.00 129.15 ?  242 ILE A O   1 
ATOM   1922 C CB  . ILE A 1 235 ? 130.950 122.179 100.059 1.00 126.22 ?  242 ILE A CB  1 
ATOM   1923 C CG1 . ILE A 1 235 ? 131.630 120.997 99.367  1.00 127.33 ?  242 ILE A CG1 1 
ATOM   1924 C CG2 . ILE A 1 235 ? 129.467 122.216 99.722  1.00 122.24 ?  242 ILE A CG2 1 
ATOM   1925 C CD1 . ILE A 1 235 ? 131.324 120.899 97.891  1.00 126.51 ?  242 ILE A CD1 1 
ATOM   1926 N N   . CYS A 1 236 ? 130.343 125.243 100.772 1.00 130.48 ?  243 CYS A N   1 
ATOM   1927 C CA  . CYS A 1 236 ? 129.354 126.310 100.807 1.00 127.09 ?  243 CYS A CA  1 
ATOM   1928 C C   . CYS A 1 236 ? 129.895 127.631 100.278 1.00 128.98 ?  243 CYS A C   1 
ATOM   1929 O O   . CYS A 1 236 ? 129.129 128.415 99.710  1.00 134.10 ?  243 CYS A O   1 
ATOM   1930 C CB  . CYS A 1 236 ? 128.833 126.496 102.231 1.00 126.29 ?  243 CYS A CB  1 
ATOM   1931 S SG  . CYS A 1 236 ? 127.592 125.278 102.718 1.00 140.21 ?  243 CYS A SG  1 
ATOM   1932 N N   . PHE A 1 237 ? 131.189 127.910 100.441 1.00 120.86 ?  244 PHE A N   1 
ATOM   1933 C CA  . PHE A 1 237 ? 131.697 129.233 100.105 1.00 115.67 ?  244 PHE A CA  1 
ATOM   1934 C C   . PHE A 1 237 ? 132.575 129.281 98.860  1.00 120.02 ?  244 PHE A C   1 
ATOM   1935 O O   . PHE A 1 237 ? 132.989 130.375 98.467  1.00 123.27 ?  244 PHE A O   1 
ATOM   1936 C CB  . PHE A 1 237 ? 132.463 129.809 101.297 1.00 116.73 ?  244 PHE A CB  1 
ATOM   1937 C CG  . PHE A 1 237 ? 131.580 130.250 102.422 1.00 118.86 ?  244 PHE A CG  1 
ATOM   1938 C CD1 . PHE A 1 237 ? 130.872 131.429 102.338 1.00 121.13 ?  244 PHE A CD1 1 
ATOM   1939 C CD2 . PHE A 1 237 ? 131.455 129.480 103.562 1.00 121.89 ?  244 PHE A CD2 1 
ATOM   1940 C CE1 . PHE A 1 237 ? 130.057 131.833 103.368 1.00 122.49 ?  244 PHE A CE1 1 
ATOM   1941 C CE2 . PHE A 1 237 ? 130.643 129.882 104.596 1.00 121.31 ?  244 PHE A CE2 1 
ATOM   1942 C CZ  . PHE A 1 237 ? 129.943 131.059 104.499 1.00 122.47 ?  244 PHE A CZ  1 
ATOM   1943 N N   . LEU A 1 238 ? 132.870 128.150 98.224  1.00 126.69 ?  245 LEU A N   1 
ATOM   1944 C CA  . LEU A 1 238 ? 133.720 128.161 97.037  1.00 127.57 ?  245 LEU A CA  1 
ATOM   1945 C C   . LEU A 1 238 ? 132.988 128.517 95.742  1.00 131.27 ?  245 LEU A C   1 
ATOM   1946 O O   . LEU A 1 238 ? 133.526 129.291 94.938  1.00 133.08 ?  245 LEU A O   1 
ATOM   1947 C CB  . LEU A 1 238 ? 134.414 126.804 96.883  1.00 127.28 ?  245 LEU A CB  1 
ATOM   1948 C CG  . LEU A 1 238 ? 135.171 126.562 95.577  1.00 131.00 ?  245 LEU A CG  1 
ATOM   1949 C CD1 . LEU A 1 238 ? 136.510 127.279 95.593  1.00 126.80 ?  245 LEU A CD1 1 
ATOM   1950 C CD2 . LEU A 1 238 ? 135.359 125.075 95.336  1.00 127.91 ?  245 LEU A CD2 1 
ATOM   1951 N N   . PRO A 1 239 ? 131.800 127.961 95.466  1.00 129.10 ?  246 PRO A N   1 
ATOM   1952 C CA  . PRO A 1 239 ? 131.173 128.241 94.159  1.00 129.59 ?  246 PRO A CA  1 
ATOM   1953 C C   . PRO A 1 239 ? 130.876 129.713 93.923  1.00 132.01 ?  246 PRO A C   1 
ATOM   1954 O O   . PRO A 1 239 ? 131.157 130.235 92.834  1.00 133.06 ?  246 PRO A O   1 
ATOM   1955 C CB  . PRO A 1 239 ? 129.896 127.392 94.205  1.00 129.15 ?  246 PRO A CB  1 
ATOM   1956 C CG  . PRO A 1 239 ? 130.182 126.330 95.187  1.00 128.79 ?  246 PRO A CG  1 
ATOM   1957 C CD  . PRO A 1 239 ? 131.001 126.990 96.234  1.00 124.89 ?  246 PRO A CD  1 
ATOM   1958 N N   . SER A 1 240 ? 130.323 130.407 94.918  1.00 133.18 ?  247 SER A N   1 
ATOM   1959 C CA  . SER A 1 240 ? 130.005 131.817 94.730  1.00 128.06 ?  247 SER A CA  1 
ATOM   1960 C C   . SER A 1 240 ? 131.262 132.633 94.458  1.00 132.47 ?  247 SER A C   1 
ATOM   1961 O O   . SER A 1 240 ? 131.277 133.482 93.559  1.00 137.46 ?  247 SER A O   1 
ATOM   1962 C CB  . SER A 1 240 ? 129.264 132.356 95.952  1.00 130.77 ?  247 SER A CB  1 
ATOM   1963 O OG  . SER A 1 240 ? 129.902 131.961 97.153  1.00 132.47 ?  247 SER A OG  1 
ATOM   1964 N N   . VAL A 1 241 ? 132.337 132.375 95.204  1.00 129.28 ?  248 VAL A N   1 
ATOM   1965 C CA  . VAL A 1 241 ? 133.543 133.177 95.035  1.00 127.66 ?  248 VAL A CA  1 
ATOM   1966 C C   . VAL A 1 241 ? 134.224 132.862 93.708  1.00 127.60 ?  248 VAL A C   1 
ATOM   1967 O O   . VAL A 1 241 ? 134.788 133.754 93.067  1.00 134.04 ?  248 VAL A O   1 
ATOM   1968 C CB  . VAL A 1 241 ? 134.495 132.999 96.232  1.00 126.98 ?  248 VAL A CB  1 
ATOM   1969 C CG1 . VAL A 1 241 ? 133.785 133.358 97.522  1.00 125.07 ?  248 VAL A CG1 1 
ATOM   1970 C CG2 . VAL A 1 241 ? 135.039 131.593 96.295  1.00 126.59 ?  248 VAL A CG2 1 
ATOM   1971 N N   . VAL A 1 242 ? 134.187 131.603 93.263  1.00 131.24 ?  249 VAL A N   1 
ATOM   1972 C CA  . VAL A 1 242 ? 134.812 131.295 91.979  1.00 136.33 ?  249 VAL A CA  1 
ATOM   1973 C C   . VAL A 1 242 ? 134.013 131.916 90.836  1.00 139.58 ?  249 VAL A C   1 
ATOM   1974 O O   . VAL A 1 242 ? 134.586 132.405 89.850  1.00 137.35 ?  249 VAL A O   1 
ATOM   1975 C CB  . VAL A 1 242 ? 135.007 129.775 91.802  1.00 137.12 ?  249 VAL A CB  1 
ATOM   1976 C CG1 . VAL A 1 242 ? 133.688 129.048 91.646  1.00 133.01 ?  249 VAL A CG1 1 
ATOM   1977 C CG2 . VAL A 1 242 ? 135.918 129.493 90.616  1.00 135.41 ?  249 VAL A CG2 1 
ATOM   1978 N N   . VAL A 1 243 ? 132.683 131.941 90.954  1.00 141.89 ?  250 VAL A N   1 
ATOM   1979 C CA  . VAL A 1 243 ? 131.894 132.618 89.930  1.00 137.18 ?  250 VAL A CA  1 
ATOM   1980 C C   . VAL A 1 243 ? 132.158 134.118 89.963  1.00 136.01 ?  250 VAL A C   1 
ATOM   1981 O O   . VAL A 1 243 ? 132.167 134.777 88.921  1.00 140.29 ?  250 VAL A O   1 
ATOM   1982 C CB  . VAL A 1 243 ? 130.398 132.297 90.079  1.00 132.93 ?  250 VAL A CB  1 
ATOM   1983 C CG1 . VAL A 1 243 ? 129.622 133.000 88.992  1.00 136.70 ?  250 VAL A CG1 1 
ATOM   1984 C CG2 . VAL A 1 243 ? 130.169 130.807 89.982  1.00 132.66 ?  250 VAL A CG2 1 
ATOM   1985 N N   . ARG A 1 244 ? 132.383 134.685 91.151  1.00 139.61 ?  251 ARG A N   1 
ATOM   1986 C CA  . ARG A 1 244 ? 132.746 136.099 91.231  1.00 139.51 ?  251 ARG A CA  1 
ATOM   1987 C C   . ARG A 1 244 ? 134.095 136.360 90.572  1.00 142.64 ?  251 ARG A C   1 
ATOM   1988 O O   . ARG A 1 244 ? 134.300 137.407 89.941  1.00 143.51 ?  251 ARG A O   1 
ATOM   1989 C CB  . ARG A 1 244 ? 132.767 136.557 92.687  1.00 139.12 ?  251 ARG A CB  1 
ATOM   1990 C CG  . ARG A 1 244 ? 132.552 138.046 92.860  1.00 140.63 ?  251 ARG A CG  1 
ATOM   1991 C CD  . ARG A 1 244 ? 131.078 138.388 92.795  1.00 144.64 ?  251 ARG A CD  1 
ATOM   1992 N NE  . ARG A 1 244 ? 130.854 139.806 92.543  1.00 146.17 ?  251 ARG A NE  1 
ATOM   1993 C CZ  . ARG A 1 244 ? 129.970 140.280 91.676  1.00 142.71 ?  251 ARG A CZ  1 
ATOM   1994 N NH1 . ARG A 1 244 ? 129.201 139.475 90.963  1.00 141.31 1  251 ARG A NH1 1 
ATOM   1995 N NH2 . ARG A 1 244 ? 129.856 141.596 91.520  1.00 139.77 ?  251 ARG A NH2 1 
ATOM   1996 N N   . ILE A 1 245 ? 135.032 135.426 90.725  1.00 149.56 ?  252 ILE A N   1 
ATOM   1997 C CA  . ILE A 1 245 ? 136.325 135.553 90.059  1.00 148.06 ?  252 ILE A CA  1 
ATOM   1998 C C   . ILE A 1 245 ? 136.137 135.551 88.549  1.00 146.91 ?  252 ILE A C   1 
ATOM   1999 O O   . ILE A 1 245 ? 136.753 136.346 87.830  1.00 150.20 ?  252 ILE A O   1 
ATOM   2000 C CB  . ILE A 1 245 ? 137.275 134.432 90.522  1.00 146.20 ?  252 ILE A CB  1 
ATOM   2001 C CG1 . ILE A 1 245 ? 137.774 134.715 91.939  1.00 145.54 ?  252 ILE A CG1 1 
ATOM   2002 C CG2 . ILE A 1 245 ? 138.451 134.298 89.572  1.00 145.31 ?  252 ILE A CG2 1 
ATOM   2003 C CD1 . ILE A 1 245 ? 137.963 133.476 92.777  1.00 143.98 ?  252 ILE A CD1 1 
ATOM   2004 N N   . ARG A 1 246 ? 135.274 134.666 88.045  1.00 148.49 ?  253 ARG A N   1 
ATOM   2005 C CA  . ARG A 1 246 ? 134.980 134.676 86.613  1.00 152.02 ?  253 ARG A CA  1 
ATOM   2006 C C   . ARG A 1 246 ? 134.277 135.969 86.201  1.00 155.29 ?  253 ARG A C   1 
ATOM   2007 O O   . ARG A 1 246 ? 134.487 136.472 85.090  1.00 153.55 ?  253 ARG A O   1 
ATOM   2008 C CB  . ARG A 1 246 ? 134.142 133.456 86.234  1.00 151.85 ?  253 ARG A CB  1 
ATOM   2009 C CG  . ARG A 1 246 ? 133.981 133.249 84.729  1.00 154.29 ?  253 ARG A CG  1 
ATOM   2010 C CD  . ARG A 1 246 ? 135.244 133.632 83.961  1.00 154.10 ?  253 ARG A CD  1 
ATOM   2011 N NE  . ARG A 1 246 ? 136.147 132.506 83.763  1.00 156.31 ?  253 ARG A NE  1 
ATOM   2012 C CZ  . ARG A 1 246 ? 136.092 131.674 82.732  1.00 155.52 ?  253 ARG A CZ  1 
ATOM   2013 N NH1 . ARG A 1 246 ? 135.182 131.811 81.781  1.00 153.88 1  253 ARG A NH1 1 
ATOM   2014 N NH2 . ARG A 1 246 ? 136.973 130.682 82.651  1.00 153.51 ?  253 ARG A NH2 1 
ATOM   2015 N N   . ILE A 1 247 ? 133.433 136.515 87.080  1.00 157.91 ?  254 ILE A N   1 
ATOM   2016 C CA  . ILE A 1 247 ? 132.805 137.810 86.823  1.00 154.84 ?  254 ILE A CA  1 
ATOM   2017 C C   . ILE A 1 247 ? 133.868 138.867 86.584  1.00 153.57 ?  254 ILE A C   1 
ATOM   2018 O O   . ILE A 1 247 ? 133.827 139.602 85.593  1.00 153.55 ?  254 ILE A O   1 
ATOM   2019 C CB  . ILE A 1 247 ? 131.884 138.210 87.992  1.00 155.67 ?  254 ILE A CB  1 
ATOM   2020 C CG1 . ILE A 1 247 ? 130.597 137.392 88.008  1.00 153.43 ?  254 ILE A CG1 1 
ATOM   2021 C CG2 . ILE A 1 247 ? 131.547 139.691 87.925  1.00 154.03 ?  254 ILE A CG2 1 
ATOM   2022 C CD1 . ILE A 1 247 ? 130.130 136.996 86.657  1.00 149.67 ?  254 ILE A CD1 1 
ATOM   2023 N N   . PHE A 1 248 ? 134.843 138.950 87.489  1.00 157.78 ?  255 PHE A N   1 
ATOM   2024 C CA  . PHE A 1 248 ? 135.898 139.949 87.345  1.00 159.91 ?  255 PHE A CA  1 
ATOM   2025 C C   . PHE A 1 248 ? 136.739 139.688 86.100  1.00 160.46 ?  255 PHE A C   1 
ATOM   2026 O O   . PHE A 1 248 ? 137.137 140.630 85.399  1.00 159.77 ?  255 PHE A O   1 
ATOM   2027 C CB  . PHE A 1 248 ? 136.773 139.975 88.596  1.00 158.51 ?  255 PHE A CB  1 
ATOM   2028 C CG  . PHE A 1 248 ? 136.275 140.908 89.660  1.00 159.94 ?  255 PHE A CG  1 
ATOM   2029 C CD1 . PHE A 1 248 ? 135.982 142.228 89.357  1.00 159.71 ?  255 PHE A CD1 1 
ATOM   2030 C CD2 . PHE A 1 248 ? 136.096 140.469 90.960  1.00 157.29 ?  255 PHE A CD2 1 
ATOM   2031 C CE1 . PHE A 1 248 ? 135.523 143.091 90.330  1.00 158.39 ?  255 PHE A CE1 1 
ATOM   2032 C CE2 . PHE A 1 248 ? 135.637 141.329 91.938  1.00 156.04 ?  255 PHE A CE2 1 
ATOM   2033 C CZ  . PHE A 1 248 ? 135.350 142.641 91.622  1.00 158.16 ?  255 PHE A CZ  1 
ATOM   2034 N N   . TRP A 1 249 ? 137.017 138.415 85.810  1.00 167.66 ?  256 TRP A N   1 
ATOM   2035 C CA  . TRP A 1 249 ? 137.802 138.067 84.631  1.00 166.56 ?  256 TRP A CA  1 
ATOM   2036 C C   . TRP A 1 249 ? 137.123 138.549 83.356  1.00 168.66 ?  256 TRP A C   1 
ATOM   2037 O O   . TRP A 1 249 ? 137.734 139.237 82.532  1.00 168.45 ?  256 TRP A O   1 
ATOM   2038 C CB  . TRP A 1 249 ? 138.028 136.555 84.579  1.00 166.58 ?  256 TRP A CB  1 
ATOM   2039 C CG  . TRP A 1 249 ? 139.064 136.139 83.575  1.00 169.65 ?  256 TRP A CG  1 
ATOM   2040 C CD1 . TRP A 1 249 ? 138.887 135.292 82.520  1.00 167.91 ?  256 TRP A CD1 1 
ATOM   2041 C CD2 . TRP A 1 249 ? 140.437 136.548 83.535  1.00 171.52 ?  256 TRP A CD2 1 
ATOM   2042 N NE1 . TRP A 1 249 ? 140.062 135.152 81.823  1.00 168.06 ?  256 TRP A NE1 1 
ATOM   2043 C CE2 . TRP A 1 249 ? 141.029 135.913 82.426  1.00 171.70 ?  256 TRP A CE2 1 
ATOM   2044 C CE3 . TRP A 1 249 ? 141.223 137.391 84.327  1.00 167.79 ?  256 TRP A CE3 1 
ATOM   2045 C CZ2 . TRP A 1 249 ? 142.370 136.093 82.091  1.00 169.24 ?  256 TRP A CZ2 1 
ATOM   2046 C CZ3 . TRP A 1 249 ? 142.553 137.570 83.992  1.00 166.53 ?  256 TRP A CZ3 1 
ATOM   2047 C CH2 . TRP A 1 249 ? 143.113 136.923 82.884  1.00 167.68 ?  256 TRP A CH2 1 
ATOM   2048 N N   . LEU A 1 250 ? 135.848 138.198 83.179  1.00 170.15 ?  257 LEU A N   1 
ATOM   2049 C CA  . LEU A 1 250 ? 135.122 138.639 81.992  1.00 169.11 ?  257 LEU A CA  1 
ATOM   2050 C C   . LEU A 1 250 ? 134.966 140.153 81.976  1.00 168.92 ?  257 LEU A C   1 
ATOM   2051 O O   . LEU A 1 250 ? 135.016 140.781 80.912  1.00 168.41 ?  257 LEU A O   1 
ATOM   2052 C CB  . LEU A 1 250 ? 133.754 137.962 81.928  1.00 167.80 ?  257 LEU A CB  1 
ATOM   2053 C CG  . LEU A 1 250 ? 133.733 136.439 81.814  1.00 167.55 ?  257 LEU A CG  1 
ATOM   2054 C CD1 . LEU A 1 250 ? 132.374 135.974 81.316  1.00 165.90 ?  257 LEU A CD1 1 
ATOM   2055 C CD2 . LEU A 1 250 ? 134.843 135.947 80.897  1.00 168.85 ?  257 LEU A CD2 1 
ATOM   2056 N N   . LEU A 1 251 ? 134.782 140.755 83.152  1.00 174.54 ?  258 LEU A N   1 
ATOM   2057 C CA  . LEU A 1 251 ? 134.569 142.193 83.245  1.00 175.64 ?  258 LEU A CA  1 
ATOM   2058 C C   . LEU A 1 251 ? 135.774 142.966 82.735  1.00 175.25 ?  258 LEU A C   1 
ATOM   2059 O O   . LEU A 1 251 ? 135.644 143.856 81.888  1.00 174.07 ?  258 LEU A O   1 
ATOM   2060 C CB  . LEU A 1 251 ? 134.279 142.560 84.697  1.00 175.20 ?  258 LEU A CB  1 
ATOM   2061 C CG  . LEU A 1 251 ? 133.713 143.932 85.033  1.00 174.01 ?  258 LEU A CG  1 
ATOM   2062 C CD1 . LEU A 1 251 ? 132.554 144.293 84.124  1.00 172.38 ?  258 LEU A CD1 1 
ATOM   2063 C CD2 . LEU A 1 251 ? 133.292 143.904 86.476  1.00 173.60 ?  258 LEU A CD2 1 
ATOM   2064 N N   . HIS A 1 252 ? 136.962 142.641 83.243  1.00 176.98 ?  259 HIS A N   1 
ATOM   2065 C CA  . HIS A 1 252 ? 138.163 143.395 82.912  1.00 177.23 ?  259 HIS A CA  1 
ATOM   2066 C C   . HIS A 1 252 ? 139.028 142.687 81.876  1.00 176.09 ?  259 HIS A C   1 
ATOM   2067 O O   . HIS A 1 252 ? 140.194 143.051 81.694  1.00 174.20 ?  259 HIS A O   1 
ATOM   2068 C CB  . HIS A 1 252 ? 138.965 143.690 84.179  1.00 176.77 ?  259 HIS A CB  1 
ATOM   2069 C CG  . HIS A 1 252 ? 138.306 144.684 85.085  1.00 178.04 ?  259 HIS A CG  1 
ATOM   2070 N ND1 . HIS A 1 252 ? 138.092 145.996 84.719  1.00 177.93 ?  259 HIS A ND1 1 
ATOM   2071 C CD2 . HIS A 1 252 ? 137.807 144.557 86.337  1.00 177.22 ?  259 HIS A CD2 1 
ATOM   2072 C CE1 . HIS A 1 252 ? 137.494 146.635 85.708  1.00 175.83 ?  259 HIS A CE1 1 
ATOM   2073 N NE2 . HIS A 1 252 ? 137.310 145.785 86.702  1.00 177.47 ?  259 HIS A NE2 1 
ATOM   2074 N N   . THR A 1 253 ? 138.483 141.680 81.193  1.00 176.40 ?  260 THR A N   1 
ATOM   2075 C CA  . THR A 1 253 ? 139.208 140.996 80.129  1.00 178.21 ?  260 THR A CA  1 
ATOM   2076 C C   . THR A 1 253 ? 138.560 141.200 78.767  1.00 178.49 ?  260 THR A C   1 
ATOM   2077 O O   . THR A 1 253 ? 139.213 141.717 77.854  1.00 176.49 ?  260 THR A O   1 
ATOM   2078 C CB  . THR A 1 253 ? 139.313 139.500 80.452  1.00 175.58 ?  260 THR A CB  1 
ATOM   2079 O OG1 . THR A 1 253 ? 140.146 139.317 81.603  1.00 175.45 ?  260 THR A OG1 1 
ATOM   2080 C CG2 . THR A 1 253 ? 139.903 138.738 79.276  1.00 173.94 ?  260 THR A CG2 1 
ATOM   2081 N N   . SER A 1 254 ? 137.293 140.821 78.597  1.00 179.39 ?  261 SER A N   1 
ATOM   2082 C CA  . SER A 1 254 ? 136.646 140.879 77.291  1.00 178.66 ?  261 SER A CA  1 
ATOM   2083 C C   . SER A 1 254 ? 135.425 141.784 77.264  1.00 178.05 ?  261 SER A C   1 
ATOM   2084 O O   . SER A 1 254 ? 135.352 142.692 76.427  1.00 176.38 ?  261 SER A O   1 
ATOM   2085 C CB  . SER A 1 254 ? 136.255 139.462 76.841  1.00 177.17 ?  261 SER A CB  1 
ATOM   2086 O OG  . SER A 1 254 ? 137.262 138.889 76.026  1.00 175.47 ?  261 SER A OG  1 
ATOM   2087 N N   . GLY A 1 255 ? 134.460 141.566 78.153  1.00 185.42 ?  262 GLY A N   1 
ATOM   2088 C CA  . GLY A 1 255 ? 133.211 142.300 78.106  1.00 185.11 ?  262 GLY A CA  1 
ATOM   2089 C C   . GLY A 1 255 ? 133.175 143.541 78.973  1.00 185.44 ?  262 GLY A C   1 
ATOM   2090 O O   . GLY A 1 255 ? 132.245 143.722 79.765  1.00 183.76 ?  262 GLY A O   1 
ATOM   2091 N N   . THR A 1 256 ? 134.182 144.406 78.833  1.00 188.57 ?  263 THR A N   1 
ATOM   2092 C CA  . THR A 1 256 ? 134.244 145.616 79.646  1.00 188.68 ?  263 THR A CA  1 
ATOM   2093 C C   . THR A 1 256 ? 133.064 146.538 79.359  1.00 188.05 ?  263 THR A C   1 
ATOM   2094 O O   . THR A 1 256 ? 132.443 147.078 80.281  1.00 186.66 ?  263 THR A O   1 
ATOM   2095 C CB  . THR A 1 256 ? 135.568 146.342 79.404  1.00 187.29 ?  263 THR A CB  1 
ATOM   2096 O OG1 . THR A 1 256 ? 136.532 145.420 78.881  1.00 185.29 ?  263 THR A OG1 1 
ATOM   2097 C CG2 . THR A 1 256 ? 136.096 146.934 80.702  1.00 185.41 ?  263 THR A CG2 1 
ATOM   2098 N N   . GLN A 1 257 ? 132.740 146.729 78.080  1.00 188.98 ?  264 GLN A N   1 
ATOM   2099 C CA  . GLN A 1 257 ? 131.631 147.589 77.679  1.00 189.04 ?  264 GLN A CA  1 
ATOM   2100 C C   . GLN A 1 257 ? 130.385 146.785 77.322  1.00 188.35 ?  264 GLN A C   1 
ATOM   2101 O O   . GLN A 1 257 ? 129.325 146.977 77.924  1.00 186.28 ?  264 GLN A O   1 
ATOM   2102 C CB  . GLN A 1 257 ? 132.056 148.476 76.500  1.00 187.11 ?  264 GLN A CB  1 
ATOM   2103 C CG  . GLN A 1 257 ? 133.354 149.235 76.729  1.00 186.19 ?  264 GLN A CG  1 
ATOM   2104 C CD  . GLN A 1 257 ? 133.320 150.087 77.985  1.00 187.90 ?  264 GLN A CD  1 
ATOM   2105 O OE1 . GLN A 1 257 ? 133.718 149.643 79.061  1.00 188.71 ?  264 GLN A OE1 1 
ATOM   2106 N NE2 . GLN A 1 257 ? 132.847 151.321 77.850  1.00 186.32 ?  264 GLN A NE2 1 
ATOM   2107 N N   . ASN A 1 258 ? 130.497 145.880 76.353  1.00 188.45 ?  265 ASN A N   1 
ATOM   2108 C CA  . ASN A 1 258 ? 129.357 145.078 75.932  1.00 187.83 ?  265 ASN A CA  1 
ATOM   2109 C C   . ASN A 1 258 ? 129.238 143.885 76.873  1.00 189.62 ?  265 ASN A C   1 
ATOM   2110 O O   . ASN A 1 258 ? 130.242 143.254 77.219  1.00 187.88 ?  265 ASN A O   1 
ATOM   2111 C CB  . ASN A 1 258 ? 129.537 144.626 74.480  1.00 186.89 ?  265 ASN A CB  1 
ATOM   2112 C CG  . ASN A 1 258 ? 128.489 143.613 74.025  1.00 188.32 ?  265 ASN A CG  1 
ATOM   2113 O OD1 . ASN A 1 258 ? 127.607 143.204 74.782  1.00 189.15 ?  265 ASN A OD1 1 
ATOM   2114 N ND2 . ASN A 1 258 ? 128.593 143.200 72.767  1.00 187.67 ?  265 ASN A ND2 1 
ATOM   2115 N N   . CYS A 1 259 ? 128.012 143.577 77.285  1.00 190.61 ?  266 CYS A N   1 
ATOM   2116 C CA  . CYS A 1 259 ? 127.742 142.554 78.291  1.00 189.19 ?  266 CYS A CA  1 
ATOM   2117 C C   . CYS A 1 259 ? 126.619 141.633 77.836  1.00 187.41 ?  266 CYS A C   1 
ATOM   2118 O O   . CYS A 1 259 ? 125.656 141.372 78.560  1.00 186.58 ?  266 CYS A O   1 
ATOM   2119 C CB  . CYS A 1 259 ? 127.414 143.193 79.635  1.00 188.43 ?  266 CYS A CB  1 
ATOM   2120 S SG  . CYS A 1 259 ? 126.041 144.356 79.589  1.00 193.47 ?  266 CYS A SG  1 
ATOM   2121 N N   . GLU A 1 260 ? 126.731 141.125 76.610  1.00 186.79 ?  267 GLU A N   1 
ATOM   2122 C CA  . GLU A 1 260 ? 125.735 140.227 76.045  1.00 187.40 ?  267 GLU A CA  1 
ATOM   2123 C C   . GLU A 1 260 ? 125.983 138.765 76.412  1.00 188.91 ?  267 GLU A C   1 
ATOM   2124 O O   . GLU A 1 260 ? 125.235 137.888 75.963  1.00 188.04 ?  267 GLU A O   1 
ATOM   2125 C CB  . GLU A 1 260 ? 125.684 140.395 74.523  1.00 186.52 ?  267 GLU A CB  1 
ATOM   2126 C CG  . GLU A 1 260 ? 126.671 139.541 73.716  1.00 187.80 ?  267 GLU A CG  1 
ATOM   2127 C CD  . GLU A 1 260 ? 128.126 139.970 73.848  1.00 188.46 ?  267 GLU A CD  1 
ATOM   2128 O OE1 . GLU A 1 260 ? 128.489 140.636 74.838  1.00 190.29 ?  267 GLU A OE1 1 
ATOM   2129 O OE2 . GLU A 1 260 ? 128.918 139.636 72.941  1.00 186.94 -1 267 GLU A OE2 1 
ATOM   2130 N N   . VAL A 1 261 ? 127.005 138.482 77.217  1.00 185.53 ?  268 VAL A N   1 
ATOM   2131 C CA  . VAL A 1 261 ? 127.358 137.111 77.569  1.00 185.80 ?  268 VAL A CA  1 
ATOM   2132 C C   . VAL A 1 261 ? 127.315 136.840 79.066  1.00 184.78 ?  268 VAL A C   1 
ATOM   2133 O O   . VAL A 1 261 ? 127.672 135.728 79.484  1.00 183.03 ?  268 VAL A O   1 
ATOM   2134 C CB  . VAL A 1 261 ? 128.746 136.725 77.011  1.00 183.77 ?  268 VAL A CB  1 
ATOM   2135 C CG1 . VAL A 1 261 ? 128.843 137.070 75.535  1.00 182.86 ?  268 VAL A CG1 1 
ATOM   2136 C CG2 . VAL A 1 261 ? 129.844 137.429 77.792  1.00 182.33 ?  268 VAL A CG2 1 
ATOM   2137 N N   . TYR A 1 262 ? 126.889 137.796 79.892  1.00 175.23 ?  269 TYR A N   1 
ATOM   2138 C CA  . TYR A 1 262 ? 126.952 137.609 81.339  1.00 173.54 ?  269 TYR A CA  1 
ATOM   2139 C C   . TYR A 1 262 ? 125.707 136.951 81.921  1.00 173.41 ?  269 TYR A C   1 
ATOM   2140 O O   . TYR A 1 262 ? 125.642 136.783 83.143  1.00 173.72 ?  269 TYR A O   1 
ATOM   2141 C CB  . TYR A 1 262 ? 127.180 138.946 82.054  1.00 171.80 ?  269 TYR A CB  1 
ATOM   2142 C CG  . TYR A 1 262 ? 128.510 139.629 81.802  1.00 171.91 ?  269 TYR A CG  1 
ATOM   2143 C CD1 . TYR A 1 262 ? 129.173 139.509 80.589  1.00 173.36 ?  269 TYR A CD1 1 
ATOM   2144 C CD2 . TYR A 1 262 ? 129.096 140.411 82.789  1.00 171.68 ?  269 TYR A CD2 1 
ATOM   2145 C CE1 . TYR A 1 262 ? 130.382 140.140 80.368  1.00 173.98 ?  269 TYR A CE1 1 
ATOM   2146 C CE2 . TYR A 1 262 ? 130.305 141.047 82.579  1.00 173.39 ?  269 TYR A CE2 1 
ATOM   2147 C CZ  . TYR A 1 262 ? 130.943 140.907 81.366  1.00 174.24 ?  269 TYR A CZ  1 
ATOM   2148 O OH  . TYR A 1 262 ? 132.144 141.536 81.149  1.00 173.81 ?  269 TYR A OH  1 
ATOM   2149 N N   . ARG A 1 263 ? 124.727 136.580 81.098  1.00 175.79 ?  270 ARG A N   1 
ATOM   2150 C CA  . ARG A 1 263 ? 123.444 136.122 81.623  1.00 177.12 ?  270 ARG A CA  1 
ATOM   2151 C C   . ARG A 1 263 ? 123.601 134.831 82.419  1.00 177.65 ?  270 ARG A C   1 
ATOM   2152 O O   . ARG A 1 263 ? 123.195 134.742 83.588  1.00 178.13 ?  270 ARG A O   1 
ATOM   2153 C CB  . ARG A 1 263 ? 122.454 135.925 80.470  1.00 174.32 ?  270 ARG A CB  1 
ATOM   2154 C CG  . ARG A 1 263 ? 122.263 137.149 79.578  1.00 175.58 ?  270 ARG A CG  1 
ATOM   2155 C CD  . ARG A 1 263 ? 123.262 137.164 78.422  1.00 176.06 ?  270 ARG A CD  1 
ATOM   2156 N NE  . ARG A 1 263 ? 122.959 138.191 77.432  1.00 178.55 ?  270 ARG A NE  1 
ATOM   2157 C CZ  . ARG A 1 263 ? 122.229 137.992 76.344  1.00 177.43 ?  270 ARG A CZ  1 
ATOM   2158 N NH1 . ARG A 1 263 ? 121.699 136.810 76.073  1.00 175.41 1  270 ARG A NH1 1 
ATOM   2159 N NH2 . ARG A 1 263 ? 122.025 139.004 75.505  1.00 175.63 ?  270 ARG A NH2 1 
ATOM   2160 N N   . SER A 1 264 ? 124.218 133.822 81.801  1.00 169.22 ?  271 SER A N   1 
ATOM   2161 C CA  . SER A 1 264 ? 124.368 132.528 82.455  1.00 169.69 ?  271 SER A CA  1 
ATOM   2162 C C   . SER A 1 264 ? 125.253 132.637 83.686  1.00 167.91 ?  271 SER A C   1 
ATOM   2163 O O   . SER A 1 264 ? 124.982 132.007 84.716  1.00 165.33 ?  271 SER A O   1 
ATOM   2164 C CB  . SER A 1 264 ? 124.945 131.512 81.471  1.00 167.83 ?  271 SER A CB  1 
ATOM   2165 O OG  . SER A 1 264 ? 125.863 132.133 80.588  1.00 167.16 ?  271 SER A OG  1 
ATOM   2166 N N   . VAL A 1 265 ? 126.320 133.430 83.599  1.00 164.27 ?  272 VAL A N   1 
ATOM   2167 C CA  . VAL A 1 265 ? 127.256 133.510 84.711  1.00 164.87 ?  272 VAL A CA  1 
ATOM   2168 C C   . VAL A 1 265 ? 126.630 134.250 85.890  1.00 165.00 ?  272 VAL A C   1 
ATOM   2169 O O   . VAL A 1 265 ? 126.857 133.887 87.046  1.00 165.90 ?  272 VAL A O   1 
ATOM   2170 C CB  . VAL A 1 265 ? 128.587 134.136 84.253  1.00 165.01 ?  272 VAL A CB  1 
ATOM   2171 C CG1 . VAL A 1 265 ? 128.433 135.609 83.928  1.00 162.74 ?  272 VAL A CG1 1 
ATOM   2172 C CG2 . VAL A 1 265 ? 129.677 133.884 85.283  1.00 164.76 ?  272 VAL A CG2 1 
ATOM   2173 N N   . ASP A 1 266 ? 125.814 135.279 85.627  1.00 161.31 ?  273 ASP A N   1 
ATOM   2174 C CA  . ASP A 1 266 ? 125.095 135.941 86.714  1.00 160.80 ?  273 ASP A CA  1 
ATOM   2175 C C   . ASP A 1 266 ? 124.086 135.002 87.362  1.00 161.17 ?  273 ASP A C   1 
ATOM   2176 O O   . ASP A 1 266 ? 123.967 134.951 88.599  1.00 161.79 ?  273 ASP A O   1 
ATOM   2177 C CB  . ASP A 1 266 ? 124.390 137.191 86.191  1.00 158.91 ?  273 ASP A CB  1 
ATOM   2178 C CG  . ASP A 1 266 ? 125.118 138.465 86.546  1.00 159.40 ?  273 ASP A CG  1 
ATOM   2179 O OD1 . ASP A 1 266 ? 125.511 138.618 87.721  1.00 158.48 ?  273 ASP A OD1 1 
ATOM   2180 O OD2 . ASP A 1 266 ? 125.290 139.315 85.650  1.00 160.03 -1 273 ASP A OD2 1 
ATOM   2181 N N   . LEU A 1 267 ? 123.342 134.258 86.538  1.00 160.71 ?  274 LEU A N   1 
ATOM   2182 C CA  . LEU A 1 267 ? 122.422 133.266 87.080  1.00 161.18 ?  274 LEU A CA  1 
ATOM   2183 C C   . LEU A 1 267 ? 123.155 132.308 88.010  1.00 163.66 ?  274 LEU A C   1 
ATOM   2184 O O   . LEU A 1 267 ? 122.777 132.143 89.177  1.00 162.37 ?  274 LEU A O   1 
ATOM   2185 C CB  . LEU A 1 267 ? 121.749 132.508 85.936  1.00 160.13 ?  274 LEU A CB  1 
ATOM   2186 C CG  . LEU A 1 267 ? 120.243 132.695 85.769  1.00 162.09 ?  274 LEU A CG  1 
ATOM   2187 C CD1 . LEU A 1 267 ? 119.753 131.957 84.536  1.00 160.48 ?  274 LEU A CD1 1 
ATOM   2188 C CD2 . LEU A 1 267 ? 119.512 132.206 87.006  1.00 160.54 ?  274 LEU A CD2 1 
ATOM   2189 N N   . ALA A 1 268 ? 124.250 131.720 87.519  1.00 154.28 ?  275 ALA A N   1 
ATOM   2190 C CA  . ALA A 1 268 ? 125.019 130.775 88.319  1.00 148.86 ?  275 ALA A CA  1 
ATOM   2191 C C   . ALA A 1 268 ? 125.572 131.435 89.574  1.00 148.57 ?  275 ALA A C   1 
ATOM   2192 O O   . ALA A 1 268 ? 125.630 130.807 90.636  1.00 148.69 ?  275 ALA A O   1 
ATOM   2193 C CB  . ALA A 1 268 ? 126.150 130.180 87.481  1.00 148.59 ?  275 ALA A CB  1 
ATOM   2194 N N   . PHE A 1 269 ? 125.977 132.703 89.475  1.00 141.69 ?  276 PHE A N   1 
ATOM   2195 C CA  . PHE A 1 269 ? 126.467 133.413 90.648  1.00 140.43 ?  276 PHE A CA  1 
ATOM   2196 C C   . PHE A 1 269 ? 125.413 133.454 91.736  1.00 139.56 ?  276 PHE A C   1 
ATOM   2197 O O   . PHE A 1 269 ? 125.717 133.229 92.910  1.00 143.96 ?  276 PHE A O   1 
ATOM   2198 C CB  . PHE A 1 269 ? 126.890 134.834 90.280  1.00 140.13 ?  276 PHE A CB  1 
ATOM   2199 C CG  . PHE A 1 269 ? 127.230 135.689 91.468  1.00 139.82 ?  276 PHE A CG  1 
ATOM   2200 C CD1 . PHE A 1 269 ? 128.048 135.209 92.476  1.00 143.32 ?  276 PHE A CD1 1 
ATOM   2201 C CD2 . PHE A 1 269 ? 126.728 136.969 91.580  1.00 143.82 ?  276 PHE A CD2 1 
ATOM   2202 C CE1 . PHE A 1 269 ? 128.356 135.990 93.570  1.00 138.75 ?  276 PHE A CE1 1 
ATOM   2203 C CE2 . PHE A 1 269 ? 127.034 137.753 92.672  1.00 145.68 ?  276 PHE A CE2 1 
ATOM   2204 C CZ  . PHE A 1 269 ? 127.848 137.262 93.668  1.00 139.78 ?  276 PHE A CZ  1 
ATOM   2205 N N   . PHE A 1 270 ? 124.164 133.725 91.369  1.00 147.85 ?  277 PHE A N   1 
ATOM   2206 C CA  . PHE A 1 270 ? 123.149 133.809 92.417  1.00 149.45 ?  277 PHE A CA  1 
ATOM   2207 C C   . PHE A 1 270 ? 122.754 132.430 92.950  1.00 152.76 ?  277 PHE A C   1 
ATOM   2208 O O   . PHE A 1 270 ? 122.547 132.269 94.164  1.00 151.16 ?  277 PHE A O   1 
ATOM   2209 C CB  . PHE A 1 270 ? 121.943 134.593 91.911  1.00 147.39 ?  277 PHE A CB  1 
ATOM   2210 C CG  . PHE A 1 270 ? 122.180 136.073 91.884  1.00 150.74 ?  277 PHE A CG  1 
ATOM   2211 C CD1 . PHE A 1 270 ? 122.366 136.773 93.063  1.00 148.49 ?  277 PHE A CD1 1 
ATOM   2212 C CD2 . PHE A 1 270 ? 122.254 136.758 90.686  1.00 152.02 ?  277 PHE A CD2 1 
ATOM   2213 C CE1 . PHE A 1 270 ? 122.601 138.128 93.050  1.00 147.91 ?  277 PHE A CE1 1 
ATOM   2214 C CE2 . PHE A 1 270 ? 122.488 138.115 90.667  1.00 150.62 ?  277 PHE A CE2 1 
ATOM   2215 C CZ  . PHE A 1 270 ? 122.663 138.800 91.851  1.00 150.09 ?  277 PHE A CZ  1 
ATOM   2216 N N   . ILE A 1 271 ? 122.674 131.417 92.077  1.00 150.62 ?  278 ILE A N   1 
ATOM   2217 C CA  . ILE A 1 271 ? 122.413 130.065 92.579  1.00 148.64 ?  278 ILE A CA  1 
ATOM   2218 C C   . ILE A 1 271 ? 123.494 129.650 93.570  1.00 146.63 ?  278 ILE A C   1 
ATOM   2219 O O   . ILE A 1 271 ? 123.203 129.062 94.618  1.00 143.42 ?  278 ILE A O   1 
ATOM   2220 C CB  . ILE A 1 271 ? 122.285 129.030 91.441  1.00 147.31 ?  278 ILE A CB  1 
ATOM   2221 C CG1 . ILE A 1 271 ? 121.745 129.627 90.144  1.00 146.52 ?  278 ILE A CG1 1 
ATOM   2222 C CG2 . ILE A 1 271 ? 121.396 127.878 91.882  1.00 147.99 ?  278 ILE A CG2 1 
ATOM   2223 C CD1 . ILE A 1 271 ? 120.372 130.246 90.255  1.00 147.23 ?  278 ILE A CD1 1 
ATOM   2224 N N   . THR A 1 272 ? 124.758 129.948 93.255  1.00 142.61 ?  279 THR A N   1 
ATOM   2225 C CA  . THR A 1 272 ? 125.851 129.580 94.147  1.00 142.80 ?  279 THR A CA  1 
ATOM   2226 C C   . THR A 1 272 ? 125.874 130.444 95.401  1.00 141.90 ?  279 THR A C   1 
ATOM   2227 O O   . THR A 1 272 ? 126.291 129.976 96.465  1.00 141.06 ?  279 THR A O   1 
ATOM   2228 C CB  . THR A 1 272 ? 127.180 129.686 93.408  1.00 145.16 ?  279 THR A CB  1 
ATOM   2229 O OG1 . THR A 1 272 ? 127.325 131.008 92.878  1.00 144.48 ?  279 THR A OG1 1 
ATOM   2230 C CG2 . THR A 1 272 ? 127.230 128.680 92.269  1.00 143.68 ?  279 THR A CG2 1 
ATOM   2231 N N   . LEU A 1 273 ? 125.442 131.702 95.296  1.00 140.59 ?  280 LEU A N   1 
ATOM   2232 C CA  . LEU A 1 273 ? 125.334 132.555 96.471  1.00 140.11 ?  280 LEU A CA  1 
ATOM   2233 C C   . LEU A 1 273 ? 124.296 132.024 97.445  1.00 140.76 ?  280 LEU A C   1 
ATOM   2234 O O   . LEU A 1 273 ? 124.413 132.245 98.654  1.00 145.11 ?  280 LEU A O   1 
ATOM   2235 C CB  . LEU A 1 273 ? 124.989 133.982 96.049  1.00 138.55 ?  280 LEU A CB  1 
ATOM   2236 C CG  . LEU A 1 273 ? 125.138 135.104 97.074  1.00 135.22 ?  280 LEU A CG  1 
ATOM   2237 C CD1 . LEU A 1 273 ? 126.346 134.882 97.953  1.00 137.55 ?  280 LEU A CD1 1 
ATOM   2238 C CD2 . LEU A 1 273 ? 125.238 136.434 96.362  1.00 138.97 ?  280 LEU A CD2 1 
ATOM   2239 N N   . SER A 1 274 ? 123.275 131.330 96.937  1.00 141.83 ?  281 SER A N   1 
ATOM   2240 C CA  . SER A 1 274 ? 122.319 130.684 97.836  1.00 144.76 ?  281 SER A CA  1 
ATOM   2241 C C   . SER A 1 274 ? 123.006 129.704 98.788  1.00 147.11 ?  281 SER A C   1 
ATOM   2242 O O   . SER A 1 274 ? 122.511 129.456 99.897  1.00 144.42 ?  281 SER A O   1 
ATOM   2243 C CB  . SER A 1 274 ? 121.241 129.966 97.026  1.00 145.22 ?  281 SER A CB  1 
ATOM   2244 O OG  . SER A 1 274 ? 121.589 128.612 96.802  1.00 144.86 ?  281 SER A OG  1 
ATOM   2245 N N   . PHE A 1 275 ? 124.152 129.147 98.385  1.00 149.51 ?  282 PHE A N   1 
ATOM   2246 C CA  . PHE A 1 275 ? 124.861 128.205 99.247  1.00 146.81 ?  282 PHE A CA  1 
ATOM   2247 C C   . PHE A 1 275 ? 125.444 128.886 100.478 1.00 144.80 ?  282 PHE A C   1 
ATOM   2248 O O   . PHE A 1 275 ? 125.599 128.245 101.524 1.00 147.38 ?  282 PHE A O   1 
ATOM   2249 C CB  . PHE A 1 275 ? 125.962 127.499 98.458  1.00 145.11 ?  282 PHE A CB  1 
ATOM   2250 C CG  . PHE A 1 275 ? 125.450 126.671 97.314  1.00 146.20 ?  282 PHE A CG  1 
ATOM   2251 C CD1 . PHE A 1 275 ? 124.166 126.154 97.337  1.00 144.81 ?  282 PHE A CD1 1 
ATOM   2252 C CD2 . PHE A 1 275 ? 126.252 126.414 96.215  1.00 146.11 ?  282 PHE A CD2 1 
ATOM   2253 C CE1 . PHE A 1 275 ? 123.692 125.394 96.287  1.00 144.81 ?  282 PHE A CE1 1 
ATOM   2254 C CE2 . PHE A 1 275 ? 125.782 125.654 95.160  1.00 146.20 ?  282 PHE A CE2 1 
ATOM   2255 C CZ  . PHE A 1 275 ? 124.500 125.144 95.197  1.00 146.22 ?  282 PHE A CZ  1 
ATOM   2256 N N   . THR A 1 276 ? 125.775 130.175 100.381 1.00 129.52 ?  283 THR A N   1 
ATOM   2257 C CA  . THR A 1 276 ? 126.246 130.892 101.559 1.00 131.64 ?  283 THR A CA  1 
ATOM   2258 C C   . THR A 1 276 ? 125.171 130.951 102.633 1.00 134.29 ?  283 THR A C   1 
ATOM   2259 O O   . THR A 1 276 ? 125.477 130.841 103.825 1.00 135.07 ?  283 THR A O   1 
ATOM   2260 C CB  . THR A 1 276 ? 126.691 132.301 101.180 1.00 131.12 ?  283 THR A CB  1 
ATOM   2261 O OG1 . THR A 1 276 ? 125.697 132.902 100.346 1.00 139.21 ?  283 THR A OG1 1 
ATOM   2262 C CG2 . THR A 1 276 ? 128.004 132.252 100.424 1.00 130.73 ?  283 THR A CG2 1 
ATOM   2263 N N   . TYR A 1 277 ? 123.912 131.134 102.234 1.00 140.46 ?  284 TYR A N   1 
ATOM   2264 C CA  . TYR A 1 277 ? 122.808 131.038 103.181 1.00 139.59 ?  284 TYR A CA  1 
ATOM   2265 C C   . TYR A 1 277 ? 122.602 129.600 103.640 1.00 141.21 ?  284 TYR A C   1 
ATOM   2266 O O   . TYR A 1 277 ? 122.259 129.361 104.802 1.00 140.54 ?  284 TYR A O   1 
ATOM   2267 C CB  . TYR A 1 277 ? 121.523 131.582 102.554 1.00 141.21 ?  284 TYR A CB  1 
ATOM   2268 C CG  . TYR A 1 277 ? 121.707 132.844 101.740 1.00 140.59 ?  284 TYR A CG  1 
ATOM   2269 C CD1 . TYR A 1 277 ? 122.395 133.932 102.252 1.00 139.06 ?  284 TYR A CD1 1 
ATOM   2270 C CD2 . TYR A 1 277 ? 121.192 132.941 100.456 1.00 139.03 ?  284 TYR A CD2 1 
ATOM   2271 C CE1 . TYR A 1 277 ? 122.564 135.081 101.508 1.00 137.89 ?  284 TYR A CE1 1 
ATOM   2272 C CE2 . TYR A 1 277 ? 121.356 134.086 99.706  1.00 135.42 ?  284 TYR A CE2 1 
ATOM   2273 C CZ  . TYR A 1 277 ? 122.042 135.152 100.236 1.00 137.67 ?  284 TYR A CZ  1 
ATOM   2274 O OH  . TYR A 1 277 ? 122.208 136.295 99.491  1.00 138.16 ?  284 TYR A OH  1 
ATOM   2275 N N   . MET A 1 278 ? 122.797 128.635 102.735 1.00 153.01 ?  285 MET A N   1 
ATOM   2276 C CA  . MET A 1 278 ? 122.672 127.226 103.112 1.00 151.73 ?  285 MET A CA  1 
ATOM   2277 C C   . MET A 1 278 ? 123.639 126.862 104.233 1.00 149.16 ?  285 MET A C   1 
ATOM   2278 O O   . MET A 1 278 ? 123.328 126.023 105.088 1.00 149.00 ?  285 MET A O   1 
ATOM   2279 C CB  . MET A 1 278 ? 122.919 126.331 101.899 1.00 152.32 ?  285 MET A CB  1 
ATOM   2280 C CG  . MET A 1 278 ? 122.550 124.873 102.123 1.00 151.74 ?  285 MET A CG  1 
ATOM   2281 S SD  . MET A 1 278 ? 123.675 123.734 101.295 1.00 160.27 ?  285 MET A SD  1 
ATOM   2282 C CE  . MET A 1 278 ? 122.822 123.476 99.743  1.00 151.19 ?  285 MET A CE  1 
ATOM   2283 N N   . ASN A 1 279 ? 124.829 127.461 104.223 1.00 143.48 ?  286 ASN A N   1 
ATOM   2284 C CA  . ASN A 1 279 ? 125.789 127.213 105.294 1.00 142.69 ?  286 ASN A CA  1 
ATOM   2285 C C   . ASN A 1 279 ? 125.218 127.607 106.648 1.00 142.09 ?  286 ASN A C   1 
ATOM   2286 O O   . ASN A 1 279 ? 125.534 126.976 107.663 1.00 141.98 ?  286 ASN A O   1 
ATOM   2287 C CB  . ASN A 1 279 ? 127.097 127.957 105.006 1.00 142.68 ?  286 ASN A CB  1 
ATOM   2288 C CG  . ASN A 1 279 ? 127.910 128.249 106.259 1.00 143.87 ?  286 ASN A CG  1 
ATOM   2289 O OD1 . ASN A 1 279 ? 127.523 129.058 107.104 1.00 143.30 ?  286 ASN A OD1 1 
ATOM   2290 N ND2 . ASN A 1 279 ? 129.047 127.577 106.386 1.00 143.51 ?  286 ASN A ND2 1 
ATOM   2291 N N   . SER A 1 280 ? 124.377 128.642 106.683 1.00 145.03 ?  287 SER A N   1 
ATOM   2292 C CA  . SER A 1 280 ? 123.787 129.076 107.944 1.00 145.33 ?  287 SER A CA  1 
ATOM   2293 C C   . SER A 1 280 ? 122.903 127.991 108.545 1.00 145.32 ?  287 SER A C   1 
ATOM   2294 O O   . SER A 1 280 ? 122.905 127.786 109.764 1.00 144.83 ?  287 SER A O   1 
ATOM   2295 C CB  . SER A 1 280 ? 122.992 130.362 107.734 1.00 144.77 ?  287 SER A CB  1 
ATOM   2296 O OG  . SER A 1 280 ? 122.908 131.107 108.933 1.00 144.77 ?  287 SER A OG  1 
ATOM   2297 N N   . MET A 1 281 ? 122.127 127.297 107.711 1.00 152.06 ?  288 MET A N   1 
ATOM   2298 C CA  . MET A 1 281 ? 121.304 126.208 108.222 1.00 152.96 ?  288 MET A CA  1 
ATOM   2299 C C   . MET A 1 281 ? 122.127 124.955 108.494 1.00 153.90 ?  288 MET A C   1 
ATOM   2300 O O   . MET A 1 281 ? 121.790 124.185 109.399 1.00 153.81 ?  288 MET A O   1 
ATOM   2301 C CB  . MET A 1 281 ? 120.159 125.897 107.252 1.00 151.88 ?  288 MET A CB  1 
ATOM   2302 C CG  . MET A 1 281 ? 120.537 125.045 106.052 1.00 154.17 ?  288 MET A CG  1 
ATOM   2303 S SD  . MET A 1 281 ? 119.239 123.890 105.576 1.00 159.05 ?  288 MET A SD  1 
ATOM   2304 C CE  . MET A 1 281 ? 120.167 122.728 104.580 1.00 152.15 ?  288 MET A CE  1 
ATOM   2305 N N   . LEU A 1 282 ? 123.204 124.735 107.736 1.00 145.76 ?  289 LEU A N   1 
ATOM   2306 C CA  . LEU A 1 282 ? 124.031 123.555 107.968 1.00 143.48 ?  289 LEU A CA  1 
ATOM   2307 C C   . LEU A 1 282 ? 124.896 123.681 109.215 1.00 142.34 ?  289 LEU A C   1 
ATOM   2308 O O   . LEU A 1 282 ? 125.322 122.660 109.761 1.00 143.09 ?  289 LEU A O   1 
ATOM   2309 C CB  . LEU A 1 282 ? 124.918 123.280 106.753 1.00 144.46 ?  289 LEU A CB  1 
ATOM   2310 C CG  . LEU A 1 282 ? 124.282 122.475 105.621 1.00 144.21 ?  289 LEU A CG  1 
ATOM   2311 C CD1 . LEU A 1 282 ? 125.322 122.092 104.585 1.00 141.85 ?  289 LEU A CD1 1 
ATOM   2312 C CD2 . LEU A 1 282 ? 123.598 121.240 106.174 1.00 142.01 ?  289 LEU A CD2 1 
ATOM   2313 N N   . ASP A 1 283 ? 125.171 124.904 109.667 1.00 142.77 ?  290 ASP A N   1 
ATOM   2314 C CA  . ASP A 1 283 ? 126.057 125.093 110.815 1.00 141.66 ?  290 ASP A CA  1 
ATOM   2315 C C   . ASP A 1 283 ? 125.556 124.438 112.098 1.00 143.98 ?  290 ASP A C   1 
ATOM   2316 O O   . ASP A 1 283 ? 126.376 123.826 112.804 1.00 146.57 ?  290 ASP A O   1 
ATOM   2317 C CB  . ASP A 1 283 ? 126.312 126.589 111.023 1.00 141.09 ?  290 ASP A CB  1 
ATOM   2318 C CG  . ASP A 1 283 ? 127.709 126.997 110.629 1.00 142.45 ?  290 ASP A CG  1 
ATOM   2319 O OD1 . ASP A 1 283 ? 128.307 126.320 109.768 1.00 142.50 ?  290 ASP A OD1 1 
ATOM   2320 O OD2 . ASP A 1 283 ? 128.212 127.995 111.184 1.00 144.54 -1 290 ASP A OD2 1 
ATOM   2321 N N   . PRO A 1 284 ? 124.278 124.550 112.489 1.00 150.69 ?  291 PRO A N   1 
ATOM   2322 C CA  . PRO A 1 284 ? 123.863 123.893 113.746 1.00 150.16 ?  291 PRO A CA  1 
ATOM   2323 C C   . PRO A 1 284 ? 124.102 122.393 113.753 1.00 150.06 ?  291 PRO A C   1 
ATOM   2324 O O   . PRO A 1 284 ? 124.676 121.865 114.714 1.00 149.79 ?  291 PRO A O   1 
ATOM   2325 C CB  . PRO A 1 284 ? 122.367 124.229 113.857 1.00 151.35 ?  291 PRO A CB  1 
ATOM   2326 C CG  . PRO A 1 284 ? 122.021 125.079 112.702 1.00 152.35 ?  291 PRO A CG  1 
ATOM   2327 C CD  . PRO A 1 284 ? 123.252 125.478 111.982 1.00 151.05 ?  291 PRO A CD  1 
ATOM   2328 N N   . VAL A 1 285 ? 123.691 121.689 112.695 1.00 148.67 ?  292 VAL A N   1 
ATOM   2329 C CA  . VAL A 1 285 ? 123.838 120.238 112.649 1.00 149.91 ?  292 VAL A CA  1 
ATOM   2330 C C   . VAL A 1 285 ? 125.289 119.794 112.580 1.00 149.36 ?  292 VAL A C   1 
ATOM   2331 O O   . VAL A 1 285 ? 125.577 118.611 112.794 1.00 149.52 ?  292 VAL A O   1 
ATOM   2332 C CB  . VAL A 1 285 ? 123.056 119.657 111.452 1.00 149.90 ?  292 VAL A CB  1 
ATOM   2333 C CG1 . VAL A 1 285 ? 123.899 119.696 110.188 1.00 146.05 ?  292 VAL A CG1 1 
ATOM   2334 C CG2 . VAL A 1 285 ? 122.596 118.240 111.753 1.00 148.22 ?  292 VAL A CG2 1 
ATOM   2335 N N   . VAL A 1 286 ? 126.214 120.707 112.293 1.00 142.57 ?  293 VAL A N   1 
ATOM   2336 C CA  . VAL A 1 286 ? 127.630 120.373 112.195 1.00 140.78 ?  293 VAL A CA  1 
ATOM   2337 C C   . VAL A 1 286 ? 128.438 120.890 113.375 1.00 139.15 ?  293 VAL A C   1 
ATOM   2338 O O   . VAL A 1 286 ? 129.595 120.470 113.542 1.00 139.75 ?  293 VAL A O   1 
ATOM   2339 C CB  . VAL A 1 286 ? 128.237 120.886 110.871 1.00 135.98 ?  293 VAL A CB  1 
ATOM   2340 C CG1 . VAL A 1 286 ? 128.696 122.323 111.012 1.00 137.99 ?  293 VAL A CG1 1 
ATOM   2341 C CG2 . VAL A 1 286 ? 129.377 119.994 110.421 1.00 133.19 ?  293 VAL A CG2 1 
ATOM   2342 N N   . TYR A 1 287 ? 127.876 121.769 114.201 1.00 134.57 ?  294 TYR A N   1 
ATOM   2343 C CA  . TYR A 1 287 ? 128.605 122.340 115.326 1.00 133.00 ?  294 TYR A CA  1 
ATOM   2344 C C   . TYR A 1 287 ? 127.967 122.031 116.671 1.00 135.65 ?  294 TYR A C   1 
ATOM   2345 O O   . TYR A 1 287 ? 128.674 121.637 117.606 1.00 134.85 ?  294 TYR A O   1 
ATOM   2346 C CB  . TYR A 1 287 ? 128.738 123.859 115.144 1.00 131.53 ?  294 TYR A CB  1 
ATOM   2347 C CG  . TYR A 1 287 ? 130.019 124.261 114.456 1.00 132.15 ?  294 TYR A CG  1 
ATOM   2348 C CD1 . TYR A 1 287 ? 131.240 124.107 115.088 1.00 132.55 ?  294 TYR A CD1 1 
ATOM   2349 C CD2 . TYR A 1 287 ? 130.008 124.780 113.171 1.00 130.18 ?  294 TYR A CD2 1 
ATOM   2350 C CE1 . TYR A 1 287 ? 132.410 124.461 114.465 1.00 133.41 ?  294 TYR A CE1 1 
ATOM   2351 C CE2 . TYR A 1 287 ? 131.177 125.138 112.539 1.00 129.34 ?  294 TYR A CE2 1 
ATOM   2352 C CZ  . TYR A 1 287 ? 132.376 124.977 113.192 1.00 133.35 ?  294 TYR A CZ  1 
ATOM   2353 O OH  . TYR A 1 287 ? 133.553 125.330 112.579 1.00 133.64 ?  294 TYR A OH  1 
ATOM   2354 N N   . TYR A 1 288 ? 126.650 122.202 116.806 1.00 150.75 ?  295 TYR A N   1 
ATOM   2355 C CA  . TYR A 1 288 ? 125.980 122.069 118.097 1.00 150.87 ?  295 TYR A CA  1 
ATOM   2356 C C   . TYR A 1 288 ? 125.313 120.709 118.276 1.00 150.82 ?  295 TYR A C   1 
ATOM   2357 O O   . TYR A 1 288 ? 125.617 119.987 119.229 1.00 151.30 ?  295 TYR A O   1 
ATOM   2358 C CB  . TYR A 1 288 ? 124.939 123.183 118.265 1.00 149.46 ?  295 TYR A CB  1 
ATOM   2359 C CG  . TYR A 1 288 ? 125.414 124.547 117.830 1.00 150.63 ?  295 TYR A CG  1 
ATOM   2360 C CD1 . TYR A 1 288 ? 126.579 125.092 118.344 1.00 149.43 ?  295 TYR A CD1 1 
ATOM   2361 C CD2 . TYR A 1 288 ? 124.693 125.290 116.906 1.00 151.63 ?  295 TYR A CD2 1 
ATOM   2362 C CE1 . TYR A 1 288 ? 127.015 126.338 117.949 1.00 150.46 ?  295 TYR A CE1 1 
ATOM   2363 C CE2 . TYR A 1 288 ? 125.123 126.538 116.505 1.00 150.80 ?  295 TYR A CE2 1 
ATOM   2364 C CZ  . TYR A 1 288 ? 126.285 127.056 117.032 1.00 150.58 ?  295 TYR A CZ  1 
ATOM   2365 O OH  . TYR A 1 288 ? 126.722 128.297 116.640 1.00 149.69 ?  295 TYR A OH  1 
ATOM   2366 N N   . PHE A 1 289 ? 124.396 120.351 117.375 1.00 160.53 ?  296 PHE A N   1 
ATOM   2367 C CA  . PHE A 1 289 ? 123.621 119.127 117.555 1.00 162.19 ?  296 PHE A CA  1 
ATOM   2368 C C   . PHE A 1 289 ? 124.501 117.888 117.459 1.00 162.18 ?  296 PHE A C   1 
ATOM   2369 O O   . PHE A 1 289 ? 124.311 116.926 118.212 1.00 162.08 ?  296 PHE A O   1 
ATOM   2370 C CB  . PHE A 1 289 ? 122.490 119.065 116.530 1.00 161.17 ?  296 PHE A CB  1 
ATOM   2371 C CG  . PHE A 1 289 ? 121.564 120.245 116.581 1.00 162.23 ?  296 PHE A CG  1 
ATOM   2372 C CD1 . PHE A 1 289 ? 121.208 120.809 117.794 1.00 161.00 ?  296 PHE A CD1 1 
ATOM   2373 C CD2 . PHE A 1 289 ? 121.051 120.791 115.418 1.00 161.95 ?  296 PHE A CD2 1 
ATOM   2374 C CE1 . PHE A 1 289 ? 120.359 121.896 117.847 1.00 161.11 ?  296 PHE A CE1 1 
ATOM   2375 C CE2 . PHE A 1 289 ? 120.201 121.876 115.465 1.00 161.54 ?  296 PHE A CE2 1 
ATOM   2376 C CZ  . PHE A 1 289 ? 119.855 122.429 116.681 1.00 161.79 ?  296 PHE A CZ  1 
ATOM   2377 N N   . SER A 1 290 ? 125.469 117.890 116.543 1.00 151.60 ?  297 SER A N   1 
ATOM   2378 C CA  . SER A 1 290 ? 126.354 116.743 116.390 1.00 150.94 ?  297 SER A CA  1 
ATOM   2379 C C   . SER A 1 290 ? 127.304 116.567 117.568 1.00 152.67 ?  297 SER A C   1 
ATOM   2380 O O   . SER A 1 290 ? 127.934 115.511 117.676 1.00 150.67 ?  297 SER A O   1 
ATOM   2381 C CB  . SER A 1 290 ? 127.157 116.872 115.096 1.00 148.14 ?  297 SER A CB  1 
ATOM   2382 O OG  . SER A 1 290 ? 128.270 117.729 115.274 1.00 146.98 ?  297 SER A OG  1 
ATOM   2383 N N   . SER A 1 291 ? 127.418 117.561 118.445 1.00 157.63 ?  298 SER A N   1 
ATOM   2384 C CA  . SER A 1 291 ? 128.315 117.451 119.583 1.00 155.94 ?  298 SER A CA  1 
ATOM   2385 C C   . SER A 1 291 ? 127.864 116.320 120.506 1.00 157.63 ?  298 SER A C   1 
ATOM   2386 O O   . SER A 1 291 ? 126.665 116.059 120.642 1.00 157.64 ?  298 SER A O   1 
ATOM   2387 C CB  . SER A 1 291 ? 128.360 118.768 120.355 1.00 155.65 ?  298 SER A CB  1 
ATOM   2388 O OG  . SER A 1 291 ? 128.487 118.540 121.748 1.00 156.22 ?  298 SER A OG  1 
ATOM   2389 N N   . PRO A 1 292 ? 128.808 115.625 121.150 1.00 157.60 ?  299 PRO A N   1 
ATOM   2390 C CA  . PRO A 1 292 ? 128.427 114.534 122.061 1.00 157.51 ?  299 PRO A CA  1 
ATOM   2391 C C   . PRO A 1 292 ? 127.620 114.991 123.264 1.00 157.08 ?  299 PRO A C   1 
ATOM   2392 O O   . PRO A 1 292 ? 126.942 114.159 123.880 1.00 153.41 ?  299 PRO A O   1 
ATOM   2393 C CB  . PRO A 1 292 ? 129.778 113.949 122.490 1.00 153.71 ?  299 PRO A CB  1 
ATOM   2394 C CG  . PRO A 1 292 ? 130.736 115.078 122.333 1.00 153.90 ?  299 PRO A CG  1 
ATOM   2395 C CD  . PRO A 1 292 ? 130.263 115.847 121.135 1.00 154.04 ?  299 PRO A CD  1 
ATOM   2396 N N   . SER A 1 293 ? 127.665 116.273 123.615 1.00 167.51 ?  300 SER A N   1 
ATOM   2397 C CA  . SER A 1 293 ? 126.917 116.798 124.749 1.00 167.26 ?  300 SER A CA  1 
ATOM   2398 C C   . SER A 1 293 ? 125.466 117.114 124.410 1.00 168.24 ?  300 SER A C   1 
ATOM   2399 O O   . SER A 1 293 ? 124.708 117.503 125.304 1.00 165.39 ?  300 SER A O   1 
ATOM   2400 C CB  . SER A 1 293 ? 127.603 118.055 125.293 1.00 164.87 ?  300 SER A CB  1 
ATOM   2401 O OG  . SER A 1 293 ? 127.439 119.147 124.406 1.00 167.30 ?  300 SER A OG  1 
ATOM   2402 N N   . PHE A 1 294 ? 125.065 116.960 123.152 1.00 170.77 ?  301 PHE A N   1 
ATOM   2403 C CA  . PHE A 1 294 ? 123.690 117.231 122.748 1.00 170.27 ?  301 PHE A CA  1 
ATOM   2404 C C   . PHE A 1 294 ? 122.902 115.936 122.573 1.00 171.06 ?  301 PHE A C   1 
ATOM   2405 O O   . PHE A 1 294 ? 121.786 115.801 123.075 1.00 169.69 ?  301 PHE A O   1 
ATOM   2406 C CB  . PHE A 1 294 ? 123.663 118.042 121.451 1.00 167.42 ?  301 PHE A CB  1 
ATOM   2407 C CG  . PHE A 1 294 ? 123.667 119.530 121.664 1.00 169.30 ?  301 PHE A CG  1 
ATOM   2408 C CD1 . PHE A 1 294 ? 124.475 120.105 122.631 1.00 169.66 ?  301 PHE A CD1 1 
ATOM   2409 C CD2 . PHE A 1 294 ? 122.868 120.356 120.890 1.00 169.82 ?  301 PHE A CD2 1 
ATOM   2410 C CE1 . PHE A 1 294 ? 124.480 121.473 122.827 1.00 168.52 ?  301 PHE A CE1 1 
ATOM   2411 C CE2 . PHE A 1 294 ? 122.871 121.725 121.080 1.00 170.01 ?  301 PHE A CE2 1 
ATOM   2412 C CZ  . PHE A 1 294 ? 123.677 122.284 122.049 1.00 169.25 ?  301 PHE A CZ  1 
ATOM   2413 O OXT . PHE A 1 294 ? 123.363 114.992 121.932 1.00 170.40 -1 301 PHE A OXT 1 
ATOM   2414 N N   . LEU B 2 1   ? 137.076 87.299  178.762 1.00 180.49 ?  4   LEU B N   1 
ATOM   2415 C CA  . LEU B 2 1   ? 137.138 87.110  177.317 1.00 182.49 ?  4   LEU B CA  1 
ATOM   2416 C C   . LEU B 2 1   ? 135.788 86.658  176.769 1.00 183.48 ?  4   LEU B C   1 
ATOM   2417 O O   . LEU B 2 1   ? 135.427 86.982  175.637 1.00 180.99 ?  4   LEU B O   1 
ATOM   2418 C CB  . LEU B 2 1   ? 138.235 86.102  176.947 1.00 183.49 ?  4   LEU B CB  1 
ATOM   2419 C CG  . LEU B 2 1   ? 138.001 84.594  177.101 1.00 183.00 ?  4   LEU B CG  1 
ATOM   2420 C CD1 . LEU B 2 1   ? 139.193 83.825  176.553 1.00 180.72 ?  4   LEU B CD1 1 
ATOM   2421 C CD2 . LEU B 2 1   ? 137.748 84.203  178.550 1.00 182.36 ?  4   LEU B CD2 1 
ATOM   2422 N N   . ASP B 2 2   ? 135.047 85.909  177.577 1.00 187.42 ?  5   ASP B N   1 
ATOM   2423 C CA  . ASP B 2 2   ? 133.695 85.479  177.242 1.00 186.21 ?  5   ASP B CA  1 
ATOM   2424 C C   . ASP B 2 2   ? 132.659 85.966  178.238 1.00 185.98 ?  5   ASP B C   1 
ATOM   2425 O O   . ASP B 2 2   ? 131.568 86.383  177.836 1.00 185.33 ?  5   ASP B O   1 
ATOM   2426 C CB  . ASP B 2 2   ? 133.631 83.947  177.146 1.00 185.67 ?  5   ASP B CB  1 
ATOM   2427 C CG  . ASP B 2 2   ? 134.354 83.259  178.289 1.00 186.21 ?  5   ASP B CG  1 
ATOM   2428 O OD1 . ASP B 2 2   ? 134.124 83.636  179.458 1.00 186.34 ?  5   ASP B OD1 1 
ATOM   2429 O OD2 . ASP B 2 2   ? 135.151 82.336  178.019 1.00 185.34 -1 5   ASP B OD2 1 
ATOM   2430 N N   . GLN B 2 3   ? 132.974 85.923  179.535 1.00 181.99 ?  6   GLN B N   1 
ATOM   2431 C CA  . GLN B 2 3   ? 132.059 86.460  180.533 1.00 181.49 ?  6   GLN B CA  1 
ATOM   2432 C C   . GLN B 2 3   ? 131.856 87.957  180.349 1.00 182.40 ?  6   GLN B C   1 
ATOM   2433 O O   . GLN B 2 3   ? 130.755 88.465  180.581 1.00 181.08 ?  6   GLN B O   1 
ATOM   2434 C CB  . GLN B 2 3   ? 132.569 86.147  181.943 1.00 179.98 ?  6   GLN B CB  1 
ATOM   2435 C CG  . GLN B 2 3   ? 133.867 86.845  182.333 1.00 180.94 ?  6   GLN B CG  1 
ATOM   2436 C CD  . GLN B 2 3   ? 135.097 86.169  181.757 1.00 181.34 ?  6   GLN B CD  1 
ATOM   2437 O OE1 . GLN B 2 3   ? 135.390 86.296  180.568 1.00 179.95 ?  6   GLN B OE1 1 
ATOM   2438 N NE2 . GLN B 2 3   ? 135.825 85.448  182.601 1.00 180.45 ?  6   GLN B NE2 1 
ATOM   2439 N N   . LEU B 2 4   ? 132.896 88.677  179.921 1.00 179.34 ?  7   LEU B N   1 
ATOM   2440 C CA  . LEU B 2 4   ? 132.746 90.102  179.646 1.00 177.06 ?  7   LEU B CA  1 
ATOM   2441 C C   . LEU B 2 4   ? 131.787 90.344  178.488 1.00 175.48 ?  7   LEU B C   1 
ATOM   2442 O O   . LEU B 2 4   ? 130.934 91.236  178.554 1.00 177.85 ?  7   LEU B O   1 
ATOM   2443 C CB  . LEU B 2 4   ? 134.109 90.722  179.347 1.00 177.71 ?  7   LEU B CB  1 
ATOM   2444 C CG  . LEU B 2 4   ? 135.120 90.709  180.492 1.00 177.26 ?  7   LEU B CG  1 
ATOM   2445 C CD1 . LEU B 2 4   ? 136.529 90.854  179.951 1.00 177.34 ?  7   LEU B CD1 1 
ATOM   2446 C CD2 . LEU B 2 4   ? 134.810 91.813  181.488 1.00 175.09 ?  7   LEU B CD2 1 
ATOM   2447 N N   . ARG B 2 5   ? 131.912 89.559  177.416 1.00 173.29 ?  8   ARG B N   1 
ATOM   2448 C CA  . ARG B 2 5   ? 130.996 89.696  176.288 1.00 175.79 ?  8   ARG B CA  1 
ATOM   2449 C C   . ARG B 2 5   ? 129.568 89.357  176.694 1.00 175.78 ?  8   ARG B C   1 
ATOM   2450 O O   . ARG B 2 5   ? 128.618 90.044  176.295 1.00 175.73 ?  8   ARG B O   1 
ATOM   2451 C CB  . ARG B 2 5   ? 131.457 88.809  175.132 1.00 176.15 ?  8   ARG B CB  1 
ATOM   2452 C CG  . ARG B 2 5   ? 130.539 88.827  173.923 1.00 175.77 ?  8   ARG B CG  1 
ATOM   2453 C CD  . ARG B 2 5   ? 131.099 87.970  172.797 1.00 177.22 ?  8   ARG B CD  1 
ATOM   2454 N NE  . ARG B 2 5   ? 131.120 86.553  173.139 1.00 178.60 ?  8   ARG B NE  1 
ATOM   2455 C CZ  . ARG B 2 5   ? 132.225 85.838  173.302 1.00 176.65 ?  8   ARG B CZ  1 
ATOM   2456 N NH1 . ARG B 2 5   ? 133.424 86.377  173.159 1.00 175.29 1  8   ARG B NH1 1 
ATOM   2457 N NH2 . ARG B 2 5   ? 132.124 84.549  173.614 1.00 175.00 ?  8   ARG B NH2 1 
ATOM   2458 N N   . GLN B 2 6   ? 129.395 88.302  177.494 1.00 171.84 ?  9   GLN B N   1 
ATOM   2459 C CA  . GLN B 2 6   ? 128.060 87.954  177.968 1.00 172.94 ?  9   GLN B CA  1 
ATOM   2460 C C   . GLN B 2 6   ? 127.473 89.068  178.826 1.00 172.76 ?  9   GLN B C   1 
ATOM   2461 O O   . GLN B 2 6   ? 126.302 89.432  178.668 1.00 172.95 ?  9   GLN B O   1 
ATOM   2462 C CB  . GLN B 2 6   ? 128.110 86.640  178.748 1.00 173.43 ?  9   GLN B CB  1 
ATOM   2463 C CG  . GLN B 2 6   ? 126.749 86.114  179.173 1.00 174.07 ?  9   GLN B CG  1 
ATOM   2464 C CD  . GLN B 2 6   ? 125.891 85.690  177.996 1.00 174.96 ?  9   GLN B CD  1 
ATOM   2465 O OE1 . GLN B 2 6   ? 124.672 85.861  178.010 1.00 174.29 ?  9   GLN B OE1 1 
ATOM   2466 N NE2 . GLN B 2 6   ? 126.524 85.133  176.970 1.00 173.28 ?  9   GLN B NE2 1 
ATOM   2467 N N   . GLU B 2 7   ? 128.279 89.636  179.726 1.00 162.25 ?  10  GLU B N   1 
ATOM   2468 C CA  . GLU B 2 7   ? 127.804 90.733  180.561 1.00 160.85 ?  10  GLU B CA  1 
ATOM   2469 C C   . GLU B 2 7   ? 127.412 91.933  179.712 1.00 161.42 ?  10  GLU B C   1 
ATOM   2470 O O   . GLU B 2 7   ? 126.367 92.551  179.943 1.00 161.57 ?  10  GLU B O   1 
ATOM   2471 C CB  . GLU B 2 7   ? 128.880 91.117  181.576 1.00 161.19 ?  10  GLU B CB  1 
ATOM   2472 C CG  . GLU B 2 7   ? 128.500 92.268  182.487 1.00 162.90 ?  10  GLU B CG  1 
ATOM   2473 C CD  . GLU B 2 7   ? 129.178 92.187  183.840 1.00 163.15 ?  10  GLU B CD  1 
ATOM   2474 O OE1 . GLU B 2 7   ? 129.556 91.069  184.249 1.00 162.73 ?  10  GLU B OE1 1 
ATOM   2475 O OE2 . GLU B 2 7   ? 129.329 93.238  184.497 1.00 161.62 -1 10  GLU B OE2 1 
ATOM   2476 N N   . ALA B 2 8   ? 128.230 92.264  178.711 1.00 161.51 ?  11  ALA B N   1 
ATOM   2477 C CA  . ALA B 2 8   ? 127.890 93.364  177.818 1.00 161.01 ?  11  ALA B CA  1 
ATOM   2478 C C   . ALA B 2 8   ? 126.570 93.099  177.113 1.00 163.06 ?  11  ALA B C   1 
ATOM   2479 O O   . ALA B 2 8   ? 125.743 94.006  176.969 1.00 163.99 ?  11  ALA B O   1 
ATOM   2480 C CB  . ALA B 2 8   ? 129.009 93.584  176.801 1.00 159.12 ?  11  ALA B CB  1 
ATOM   2481 N N   . GLU B 2 9   ? 126.350 91.855  176.679 1.00 160.54 ?  12  GLU B N   1 
ATOM   2482 C CA  . GLU B 2 9   ? 125.081 91.503  176.051 1.00 160.18 ?  12  GLU B CA  1 
ATOM   2483 C C   . GLU B 2 9   ? 123.915 91.707  177.011 1.00 158.74 ?  12  GLU B C   1 
ATOM   2484 O O   . GLU B 2 9   ? 122.849 92.190  176.610 1.00 157.11 ?  12  GLU B O   1 
ATOM   2485 C CB  . GLU B 2 9   ? 125.126 90.057  175.559 1.00 159.37 ?  12  GLU B CB  1 
ATOM   2486 C CG  . GLU B 2 9   ? 123.990 89.684  174.628 1.00 159.14 ?  12  GLU B CG  1 
ATOM   2487 C CD  . GLU B 2 9   ? 123.700 90.762  173.605 1.00 160.67 ?  12  GLU B CD  1 
ATOM   2488 O OE1 . GLU B 2 9   ? 124.589 91.052  172.777 1.00 159.26 ?  12  GLU B OE1 1 
ATOM   2489 O OE2 . GLU B 2 9   ? 122.582 91.318  173.628 1.00 161.39 -1 12  GLU B OE2 1 
ATOM   2490 N N   . GLN B 2 10  ? 124.095 91.338  178.282 1.00 160.26 ?  13  GLN B N   1 
ATOM   2491 C CA  . GLN B 2 10  ? 123.041 91.588  179.266 1.00 158.93 ?  13  GLN B CA  1 
ATOM   2492 C C   . GLN B 2 10  ? 122.769 93.078  179.433 1.00 158.69 ?  13  GLN B C   1 
ATOM   2493 O O   . GLN B 2 10  ? 121.611 93.486  179.574 1.00 157.66 ?  13  GLN B O   1 
ATOM   2494 C CB  . GLN B 2 10  ? 123.381 90.953  180.617 1.00 157.77 ?  13  GLN B CB  1 
ATOM   2495 C CG  . GLN B 2 10  ? 124.034 89.570  180.602 1.00 158.72 ?  13  GLN B CG  1 
ATOM   2496 C CD  . GLN B 2 10  ? 123.471 88.622  179.547 1.00 161.02 ?  13  GLN B CD  1 
ATOM   2497 O OE1 . GLN B 2 10  ? 123.658 88.809  178.343 1.00 162.46 ?  13  GLN B OE1 1 
ATOM   2498 N NE2 . GLN B 2 10  ? 122.771 87.591  180.005 1.00 158.54 ?  13  GLN B NE2 1 
ATOM   2499 N N   . LEU B 2 11  ? 123.815 93.907  179.445 1.00 154.08 ?  14  LEU B N   1 
ATOM   2500 C CA  . LEU B 2 11  ? 123.579 95.349  179.533 1.00 152.40 ?  14  LEU B CA  1 
ATOM   2501 C C   . LEU B 2 11  ? 122.834 95.884  178.314 1.00 151.76 ?  14  LEU B C   1 
ATOM   2502 O O   . LEU B 2 11  ? 121.944 96.730  178.456 1.00 153.83 ?  14  LEU B O   1 
ATOM   2503 C CB  . LEU B 2 11  ? 124.875 96.129  179.757 1.00 152.52 ?  14  LEU B CB  1 
ATOM   2504 C CG  . LEU B 2 11  ? 125.482 96.179  181.168 1.00 152.19 ?  14  LEU B CG  1 
ATOM   2505 C CD1 . LEU B 2 11  ? 124.379 96.378  182.200 1.00 150.60 ?  14  LEU B CD1 1 
ATOM   2506 C CD2 . LEU B 2 11  ? 126.350 95.006  181.540 1.00 152.56 ?  14  LEU B CD2 1 
ATOM   2507 N N   . LYS B 2 12  ? 123.179 95.424  177.108 1.00 146.99 ?  15  LYS B N   1 
ATOM   2508 C CA  . LYS B 2 12  ? 122.409 95.863  175.942 1.00 147.21 ?  15  LYS B CA  1 
ATOM   2509 C C   . LYS B 2 12  ? 120.958 95.412  176.041 1.00 147.29 ?  15  LYS B C   1 
ATOM   2510 O O   . LYS B 2 12  ? 120.040 96.166  175.694 1.00 144.38 ?  15  LYS B O   1 
ATOM   2511 C CB  . LYS B 2 12  ? 123.023 95.369  174.630 1.00 148.79 ?  15  LYS B CB  1 
ATOM   2512 C CG  . LYS B 2 12  ? 124.518 95.187  174.619 1.00 147.79 ?  15  LYS B CG  1 
ATOM   2513 C CD  . LYS B 2 12  ? 125.225 96.460  174.193 1.00 148.73 ?  15  LYS B CD  1 
ATOM   2514 C CE  . LYS B 2 12  ? 124.677 96.976  172.875 1.00 149.05 ?  15  LYS B CE  1 
ATOM   2515 N NZ  . LYS B 2 12  ? 125.236 98.310  172.526 1.00 148.54 1  15  LYS B NZ  1 
ATOM   2516 N N   . ASN B 2 13  ? 120.732 94.183  176.511 1.00 152.97 ?  16  ASN B N   1 
ATOM   2517 C CA  . ASN B 2 13  ? 119.368 93.694  176.682 1.00 151.71 ?  16  ASN B CA  1 
ATOM   2518 C C   . ASN B 2 13  ? 118.600 94.565  177.667 1.00 151.06 ?  16  ASN B C   1 
ATOM   2519 O O   . ASN B 2 13  ? 117.450 94.943  177.418 1.00 149.97 ?  16  ASN B O   1 
ATOM   2520 C CB  . ASN B 2 13  ? 119.392 92.242  177.159 1.00 150.47 ?  16  ASN B CB  1 
ATOM   2521 C CG  . ASN B 2 13  ? 119.408 91.252  176.016 1.00 152.17 ?  16  ASN B CG  1 
ATOM   2522 O OD1 . ASN B 2 13  ? 119.312 91.630  174.851 1.00 150.88 ?  16  ASN B OD1 1 
ATOM   2523 N ND2 . ASN B 2 13  ? 119.527 89.971  176.346 1.00 151.70 ?  16  ASN B ND2 1 
ATOM   2524 N N   . GLN B 2 14  ? 119.234 94.899  178.793 1.00 146.76 ?  17  GLN B N   1 
ATOM   2525 C CA  . GLN B 2 14  ? 118.592 95.729  179.806 1.00 144.31 ?  17  GLN B CA  1 
ATOM   2526 C C   . GLN B 2 14  ? 118.270 97.105  179.240 1.00 145.73 ?  17  GLN B C   1 
ATOM   2527 O O   . GLN B 2 14  ? 117.159 97.616  179.422 1.00 146.22 ?  17  GLN B O   1 
ATOM   2528 C CB  . GLN B 2 14  ? 119.517 95.811  181.030 1.00 143.20 ?  17  GLN B CB  1 
ATOM   2529 C CG  . GLN B 2 14  ? 118.904 96.042  182.437 1.00 144.93 ?  17  GLN B CG  1 
ATOM   2530 C CD  . GLN B 2 14  ? 117.953 97.221  182.599 1.00 146.17 ?  17  GLN B CD  1 
ATOM   2531 O OE1 . GLN B 2 14  ? 117.928 98.148  181.801 1.00 147.11 ?  17  GLN B OE1 1 
ATOM   2532 N NE2 . GLN B 2 14  ? 117.155 97.176  183.660 1.00 145.24 ?  17  GLN B NE2 1 
ATOM   2533 N N   . ILE B 2 15  ? 119.219 97.703  178.517 1.00 138.02 ?  18  ILE B N   1 
ATOM   2534 C CA  . ILE B 2 15  ? 119.015 99.038  177.963 1.00 135.11 ?  18  ILE B CA  1 
ATOM   2535 C C   . ILE B 2 15  ? 117.852 99.033  176.980 1.00 135.01 ?  18  ILE B C   1 
ATOM   2536 O O   . ILE B 2 15  ? 116.971 99.901  177.027 1.00 137.38 ?  18  ILE B O   1 
ATOM   2537 C CB  . ILE B 2 15  ? 120.310 99.545  177.305 1.00 135.64 ?  18  ILE B CB  1 
ATOM   2538 C CG1 . ILE B 2 15  ? 121.244 100.137 178.357 1.00 134.29 ?  18  ILE B CG1 1 
ATOM   2539 C CG2 . ILE B 2 15  ? 120.005 100.574 176.230 1.00 134.36 ?  18  ILE B CG2 1 
ATOM   2540 C CD1 . ILE B 2 15  ? 122.479 100.771 177.777 1.00 136.24 ?  18  ILE B CD1 1 
ATOM   2541 N N   . ARG B 2 16  ? 117.823 98.046  176.081 1.00 140.17 ?  19  ARG B N   1 
ATOM   2542 C CA  . ARG B 2 16  ? 116.750 97.999  175.094 1.00 140.44 ?  19  ARG B CA  1 
ATOM   2543 C C   . ARG B 2 16  ? 115.405 97.727  175.755 1.00 139.94 ?  19  ARG B C   1 
ATOM   2544 O O   . ARG B 2 16  ? 114.384 98.292  175.348 1.00 141.16 ?  19  ARG B O   1 
ATOM   2545 C CB  . ARG B 2 16  ? 117.052 96.948  174.027 1.00 140.78 ?  19  ARG B CB  1 
ATOM   2546 C CG  . ARG B 2 16  ? 115.978 96.850  172.953 1.00 138.73 ?  19  ARG B CG  1 
ATOM   2547 C CD  . ARG B 2 16  ? 116.035 95.569  172.116 1.00 141.71 ?  19  ARG B CD  1 
ATOM   2548 N NE  . ARG B 2 16  ? 116.986 94.567  172.586 1.00 145.49 ?  19  ARG B NE  1 
ATOM   2549 C CZ  . ARG B 2 16  ? 116.778 93.750  173.610 1.00 144.98 ?  19  ARG B CZ  1 
ATOM   2550 N NH1 . ARG B 2 16  ? 115.660 93.797  174.317 1.00 145.02 1  19  ARG B NH1 1 
ATOM   2551 N NH2 . ARG B 2 16  ? 117.712 92.860  173.929 1.00 140.70 ?  19  ARG B NH2 1 
ATOM   2552 N N   . ASP B 2 17  ? 115.382 96.874  176.783 1.00 140.92 ?  20  ASP B N   1 
ATOM   2553 C CA  . ASP B 2 17  ? 114.133 96.604  177.486 1.00 141.84 ?  20  ASP B CA  1 
ATOM   2554 C C   . ASP B 2 17  ? 113.611 97.852  178.186 1.00 143.55 ?  20  ASP B C   1 
ATOM   2555 O O   . ASP B 2 17  ? 112.409 98.130  178.155 1.00 141.75 ?  20  ASP B O   1 
ATOM   2556 C CB  . ASP B 2 17  ? 114.330 95.468  178.488 1.00 144.31 ?  20  ASP B CB  1 
ATOM   2557 C CG  . ASP B 2 17  ? 114.519 94.126  177.814 1.00 148.00 ?  20  ASP B CG  1 
ATOM   2558 O OD1 . ASP B 2 17  ? 114.105 93.986  176.644 1.00 144.31 ?  20  ASP B OD1 1 
ATOM   2559 O OD2 . ASP B 2 17  ? 115.082 93.211  178.451 1.00 149.00 -1 20  ASP B OD2 1 
ATOM   2560 N N   . ALA B 2 18  ? 114.501 98.614  178.825 1.00 138.25 ?  21  ALA B N   1 
ATOM   2561 C CA  . ALA B 2 18  ? 114.079 99.851  179.476 1.00 134.67 ?  21  ALA B CA  1 
ATOM   2562 C C   . ALA B 2 18  ? 113.572 100.863 178.457 1.00 133.90 ?  21  ALA B C   1 
ATOM   2563 O O   . ALA B 2 18  ? 112.562 101.541 178.690 1.00 132.26 ?  21  ALA B O   1 
ATOM   2564 C CB  . ALA B 2 18  ? 115.233 100.437 180.287 1.00 129.48 ?  21  ALA B CB  1 
ATOM   2565 N N   . ARG B 2 19  ? 114.259 100.976 177.319 1.00 125.95 ?  22  ARG B N   1 
ATOM   2566 C CA  . ARG B 2 19  ? 113.811 101.887 176.273 1.00 119.39 ?  22  ARG B CA  1 
ATOM   2567 C C   . ARG B 2 19  ? 112.433 101.493 175.757 1.00 123.21 ?  22  ARG B C   1 
ATOM   2568 O O   . ARG B 2 19  ? 111.572 102.354 175.543 1.00 125.87 ?  22  ARG B O   1 
ATOM   2569 C CB  . ARG B 2 19  ? 114.825 101.908 175.132 1.00 118.00 ?  22  ARG B CB  1 
ATOM   2570 C CG  . ARG B 2 19  ? 115.849 103.019 175.236 1.00 119.99 ?  22  ARG B CG  1 
ATOM   2571 C CD  . ARG B 2 19  ? 117.057 102.740 174.365 1.00 121.94 ?  22  ARG B CD  1 
ATOM   2572 N NE  . ARG B 2 19  ? 118.145 103.672 174.631 1.00 123.10 ?  22  ARG B NE  1 
ATOM   2573 C CZ  . ARG B 2 19  ? 119.305 103.671 173.990 1.00 124.44 ?  22  ARG B CZ  1 
ATOM   2574 N NH1 . ARG B 2 19  ? 119.566 102.796 173.035 1.00 125.10 1  22  ARG B NH1 1 
ATOM   2575 N NH2 . ARG B 2 19  ? 120.226 104.574 174.314 1.00 125.84 ?  22  ARG B NH2 1 
ATOM   2576 N N   . LYS B 2 20  ? 112.206 100.195 175.551 1.00 132.43 ?  23  LYS B N   1 
ATOM   2577 C CA  . LYS B 2 20  ? 110.895 99.731  175.109 1.00 132.32 ?  23  LYS B CA  1 
ATOM   2578 C C   . LYS B 2 20  ? 109.831 99.995  176.166 1.00 133.86 ?  23  LYS B C   1 
ATOM   2579 O O   . LYS B 2 20  ? 108.702 100.376 175.838 1.00 134.36 ?  23  LYS B O   1 
ATOM   2580 C CB  . LYS B 2 20  ? 110.954 98.244  174.767 1.00 132.88 ?  23  LYS B CB  1 
ATOM   2581 C CG  . LYS B 2 20  ? 109.615 97.638  174.386 1.00 132.56 ?  23  LYS B CG  1 
ATOM   2582 C CD  . LYS B 2 20  ? 109.230 97.980  172.956 1.00 133.94 ?  23  LYS B CD  1 
ATOM   2583 C CE  . LYS B 2 20  ? 110.390 97.771  171.997 1.00 133.56 ?  23  LYS B CE  1 
ATOM   2584 N NZ  . LYS B 2 20  ? 110.361 98.749  170.873 1.00 132.30 1  23  LYS B NZ  1 
ATOM   2585 N N   . ALA B 2 21  ? 110.173 99.794  177.440 1.00 132.03 ?  24  ALA B N   1 
ATOM   2586 C CA  . ALA B 2 21  ? 109.217 100.031 178.514 1.00 130.06 ?  24  ALA B CA  1 
ATOM   2587 C C   . ALA B 2 21  ? 108.804 101.494 178.571 1.00 131.63 ?  24  ALA B C   1 
ATOM   2588 O O   . ALA B 2 21  ? 107.626 101.808 178.776 1.00 130.22 ?  24  ALA B O   1 
ATOM   2589 C CB  . ALA B 2 21  ? 109.811 99.589  179.851 1.00 127.27 ?  24  ALA B CB  1 
ATOM   2590 N N   . CYS B 2 22  ? 109.758 102.406 178.392 1.00 135.29 ?  25  CYS B N   1 
ATOM   2591 C CA  . CYS B 2 22  ? 109.430 103.825 178.396 1.00 132.88 ?  25  CYS B CA  1 
ATOM   2592 C C   . CYS B 2 22  ? 108.738 104.281 177.119 1.00 130.65 ?  25  CYS B C   1 
ATOM   2593 O O   . CYS B 2 22  ? 108.251 105.414 177.073 1.00 130.47 ?  25  CYS B O   1 
ATOM   2594 C CB  . CYS B 2 22  ? 110.691 104.655 178.628 1.00 130.11 ?  25  CYS B CB  1 
ATOM   2595 S SG  . CYS B 2 22  ? 111.275 104.580 180.329 1.00 141.65 ?  25  CYS B SG  1 
ATOM   2596 N N   . ALA B 2 23  ? 108.678 103.437 176.091 1.00 132.16 ?  26  ALA B N   1 
ATOM   2597 C CA  . ALA B 2 23  ? 108.001 103.774 174.840 1.00 128.64 ?  26  ALA B CA  1 
ATOM   2598 C C   . ALA B 2 23  ? 106.538 103.376 174.965 1.00 130.92 ?  26  ALA B C   1 
ATOM   2599 O O   . ALA B 2 23  ? 106.158 102.235 174.703 1.00 132.45 ?  26  ALA B O   1 
ATOM   2600 C CB  . ALA B 2 23  ? 108.666 103.082 173.659 1.00 128.33 ?  26  ALA B CB  1 
ATOM   2601 N N   . ASP B 2 24  ? 105.701 104.332 175.369 1.00 136.65 ?  27  ASP B N   1 
ATOM   2602 C CA  . ASP B 2 24  ? 104.273 104.088 175.495 1.00 139.48 ?  27  ASP B CA  1 
ATOM   2603 C C   . ASP B 2 24  ? 103.441 104.756 174.414 1.00 138.65 ?  27  ASP B C   1 
ATOM   2604 O O   . ASP B 2 24  ? 102.297 104.345 174.200 1.00 137.25 ?  27  ASP B O   1 
ATOM   2605 C CB  . ASP B 2 24  ? 103.766 104.551 176.869 1.00 139.14 ?  27  ASP B CB  1 
ATOM   2606 C CG  . ASP B 2 24  ? 103.753 106.057 177.010 1.00 141.29 ?  27  ASP B CG  1 
ATOM   2607 O OD1 . ASP B 2 24  ? 104.604 106.724 176.389 1.00 141.24 ?  27  ASP B OD1 1 
ATOM   2608 O OD2 . ASP B 2 24  ? 102.885 106.576 177.742 1.00 140.70 -1 27  ASP B OD2 1 
ATOM   2609 N N   . ALA B 2 25  ? 103.980 105.764 173.732 1.00 134.61 ?  28  ALA B N   1 
ATOM   2610 C CA  . ALA B 2 25  ? 103.257 106.427 172.650 1.00 133.05 ?  28  ALA B CA  1 
ATOM   2611 C C   . ALA B 2 25  ? 104.257 107.180 171.792 1.00 132.09 ?  28  ALA B C   1 
ATOM   2612 O O   . ALA B 2 25  ? 104.979 108.044 172.299 1.00 130.62 ?  28  ALA B O   1 
ATOM   2613 C CB  . ALA B 2 25  ? 102.195 107.377 173.199 1.00 130.44 ?  28  ALA B CB  1 
ATOM   2614 N N   . THR B 2 26  ? 104.307 106.853 170.505 1.00 135.62 ?  29  THR B N   1 
ATOM   2615 C CA  . THR B 2 26  ? 105.116 107.619 169.571 1.00 136.65 ?  29  THR B CA  1 
ATOM   2616 C C   . THR B 2 26  ? 104.505 108.998 169.363 1.00 134.63 ?  29  THR B C   1 
ATOM   2617 O O   . THR B 2 26  ? 103.287 109.174 169.414 1.00 133.63 ?  29  THR B O   1 
ATOM   2618 C CB  . THR B 2 26  ? 105.224 106.891 168.232 1.00 135.03 ?  29  THR B CB  1 
ATOM   2619 O OG1 . THR B 2 26  ? 104.028 107.108 167.475 1.00 134.23 ?  29  THR B OG1 1 
ATOM   2620 C CG2 . THR B 2 26  ? 105.409 105.401 168.452 1.00 133.00 ?  29  THR B CG2 1 
ATOM   2621 N N   . LEU B 2 27  ? 105.364 109.990 169.126 1.00 119.14 ?  30  LEU B N   1 
ATOM   2622 C CA  . LEU B 2 27  ? 104.843 111.336 168.924 1.00 122.23 ?  30  LEU B CA  1 
ATOM   2623 C C   . LEU B 2 27  ? 104.119 111.502 167.595 1.00 123.55 ?  30  LEU B C   1 
ATOM   2624 O O   . LEU B 2 27  ? 103.501 112.549 167.381 1.00 129.54 ?  30  LEU B O   1 
ATOM   2625 C CB  . LEU B 2 27  ? 105.955 112.380 169.067 1.00 124.53 ?  30  LEU B CB  1 
ATOM   2626 C CG  . LEU B 2 27  ? 106.769 112.889 167.887 1.00 120.69 ?  30  LEU B CG  1 
ATOM   2627 C CD1 . LEU B 2 27  ? 107.657 114.029 168.327 1.00 117.30 ?  30  LEU B CD1 1 
ATOM   2628 C CD2 . LEU B 2 27  ? 107.635 111.760 167.438 1.00 125.31 ?  30  LEU B CD2 1 
ATOM   2629 N N   . SER B 2 28  ? 104.163 110.503 166.710 1.00 130.55 ?  31  SER B N   1 
ATOM   2630 C CA  . SER B 2 28  ? 103.338 110.556 165.508 1.00 131.36 ?  31  SER B CA  1 
ATOM   2631 C C   . SER B 2 28  ? 101.857 110.606 165.860 1.00 133.90 ?  31  SER B C   1 
ATOM   2632 O O   . SER B 2 28  ? 101.102 111.397 165.285 1.00 132.08 ?  31  SER B O   1 
ATOM   2633 C CB  . SER B 2 28  ? 103.628 109.353 164.612 1.00 130.71 ?  31  SER B CB  1 
ATOM   2634 O OG  . SER B 2 28  ? 103.057 108.172 165.147 1.00 134.68 ?  31  SER B OG  1 
ATOM   2635 N N   . GLN B 2 29  ? 101.423 109.769 166.804 1.00 133.31 ?  32  GLN B N   1 
ATOM   2636 C CA  . GLN B 2 29  ? 100.029 109.780 167.226 1.00 132.38 ?  32  GLN B CA  1 
ATOM   2637 C C   . GLN B 2 29  ? 99.739  110.874 168.241 1.00 132.82 ?  32  GLN B C   1 
ATOM   2638 O O   . GLN B 2 29  ? 98.568  111.126 168.543 1.00 135.91 ?  32  GLN B O   1 
ATOM   2639 C CB  . GLN B 2 29  ? 99.637  108.422 167.812 1.00 132.26 ?  32  GLN B CB  1 
ATOM   2640 C CG  . GLN B 2 29  ? 100.421 108.029 169.049 1.00 133.34 ?  32  GLN B CG  1 
ATOM   2641 C CD  . GLN B 2 29  ? 100.442 106.533 169.275 1.00 134.46 ?  32  GLN B CD  1 
ATOM   2642 O OE1 . GLN B 2 29  ? 100.482 105.751 168.327 1.00 137.00 ?  32  GLN B OE1 1 
ATOM   2643 N NE2 . GLN B 2 29  ? 100.418 106.126 170.538 1.00 132.20 ?  32  GLN B NE2 1 
ATOM   2644 N N   . ILE B 2 30  ? 100.770 111.520 168.774 1.00 124.64 ?  33  ILE B N   1 
ATOM   2645 C CA  . ILE B 2 30  ? 100.578 112.604 169.732 1.00 125.82 ?  33  ILE B CA  1 
ATOM   2646 C C   . ILE B 2 30  ? 100.407 113.944 169.026 1.00 126.62 ?  33  ILE B C   1 
ATOM   2647 O O   . ILE B 2 30  ? 99.562  114.753 169.415 1.00 127.44 ?  33  ILE B O   1 
ATOM   2648 C CB  . ILE B 2 30  ? 101.753 112.627 170.730 1.00 121.18 ?  33  ILE B CB  1 
ATOM   2649 C CG1 . ILE B 2 30  ? 101.476 111.676 171.893 1.00 122.71 ?  33  ILE B CG1 1 
ATOM   2650 C CG2 . ILE B 2 30  ? 102.002 114.026 171.245 1.00 120.70 ?  33  ILE B CG2 1 
ATOM   2651 C CD1 . ILE B 2 30  ? 102.461 111.798 173.027 1.00 123.75 ?  33  ILE B CD1 1 
ATOM   2652 N N   . THR B 2 31  ? 101.185 114.193 167.976 1.00 123.90 ?  34  THR B N   1 
ATOM   2653 C CA  . THR B 2 31  ? 101.110 115.448 167.244 1.00 123.70 ?  34  THR B CA  1 
ATOM   2654 C C   . THR B 2 31  ? 100.164 115.393 166.053 1.00 123.92 ?  34  THR B C   1 
ATOM   2655 O O   . THR B 2 31  ? 100.100 116.365 165.294 1.00 126.27 ?  34  THR B O   1 
ATOM   2656 C CB  . THR B 2 31  ? 102.500 115.864 166.753 1.00 123.38 ?  34  THR B CB  1 
ATOM   2657 O OG1 . THR B 2 31  ? 102.917 114.990 165.698 1.00 121.34 ?  34  THR B OG1 1 
ATOM   2658 C CG2 . THR B 2 31  ? 103.507 115.800 167.886 1.00 120.61 ?  34  THR B CG2 1 
ATOM   2659 N N   . ASN B 2 32  ? 99.434  114.291 165.866 1.00 133.68 ?  35  ASN B N   1 
ATOM   2660 C CA  . ASN B 2 32  ? 98.557  114.172 164.707 1.00 135.95 ?  35  ASN B CA  1 
ATOM   2661 C C   . ASN B 2 32  ? 97.421  115.186 164.729 1.00 135.79 ?  35  ASN B C   1 
ATOM   2662 O O   . ASN B 2 32  ? 96.878  115.512 163.668 1.00 134.54 ?  35  ASN B O   1 
ATOM   2663 C CB  . ASN B 2 32  ? 97.982  112.758 164.619 1.00 132.24 ?  35  ASN B CB  1 
ATOM   2664 C CG  . ASN B 2 32  ? 97.260  112.343 165.882 1.00 134.92 ?  35  ASN B CG  1 
ATOM   2665 O OD1 . ASN B 2 32  ? 97.171  113.109 166.841 1.00 133.10 ?  35  ASN B OD1 1 
ATOM   2666 N ND2 . ASN B 2 32  ? 96.733  111.125 165.888 1.00 135.76 ?  35  ASN B ND2 1 
ATOM   2667 N N   . ASN B 2 33  ? 97.048  115.690 165.906 1.00 137.50 ?  36  ASN B N   1 
ATOM   2668 C CA  . ASN B 2 33  ? 95.957  116.652 165.994 1.00 136.69 ?  36  ASN B CA  1 
ATOM   2669 C C   . ASN B 2 33  ? 96.369  118.056 165.574 1.00 135.61 ?  36  ASN B C   1 
ATOM   2670 O O   . ASN B 2 33  ? 95.492  118.905 165.383 1.00 135.03 ?  36  ASN B O   1 
ATOM   2671 C CB  . ASN B 2 33  ? 95.396  116.682 167.416 1.00 137.63 ?  36  ASN B CB  1 
ATOM   2672 C CG  . ASN B 2 33  ? 96.483  116.737 168.472 1.00 140.66 ?  36  ASN B CG  1 
ATOM   2673 O OD1 . ASN B 2 33  ? 97.408  117.544 168.388 1.00 140.09 ?  36  ASN B OD1 1 
ATOM   2674 N ND2 . ASN B 2 33  ? 96.375  115.875 169.476 1.00 136.36 ?  36  ASN B ND2 1 
ATOM   2675 N N   . ILE B 2 34  ? 97.661  118.322 165.428 1.00 124.52 ?  37  ILE B N   1 
ATOM   2676 C CA  . ILE B 2 34  ? 98.126  119.645 165.029 1.00 124.15 ?  37  ILE B CA  1 
ATOM   2677 C C   . ILE B 2 34  ? 97.901  119.840 163.537 1.00 127.87 ?  37  ILE B C   1 
ATOM   2678 O O   . ILE B 2 34  ? 98.005  118.903 162.739 1.00 128.86 ?  37  ILE B O   1 
ATOM   2679 C CB  . ILE B 2 34  ? 99.610  119.838 165.392 1.00 123.25 ?  37  ILE B CB  1 
ATOM   2680 C CG1 . ILE B 2 34  ? 99.893  119.327 166.797 1.00 122.85 ?  37  ILE B CG1 1 
ATOM   2681 C CG2 . ILE B 2 34  ? 100.001 121.299 165.284 1.00 124.62 ?  37  ILE B CG2 1 
ATOM   2682 C CD1 . ILE B 2 34  ? 101.344 119.428 167.162 1.00 124.98 ?  37  ILE B CD1 1 
ATOM   2683 N N   . ASP B 2 35  ? 97.580  121.070 163.158 1.00 129.75 ?  38  ASP B N   1 
ATOM   2684 C CA  . ASP B 2 35  ? 97.507  121.410 161.749 1.00 129.49 ?  38  ASP B CA  1 
ATOM   2685 C C   . ASP B 2 35  ? 98.914  121.484 161.160 1.00 128.61 ?  38  ASP B C   1 
ATOM   2686 O O   . ASP B 2 35  ? 99.816  122.060 161.776 1.00 127.05 ?  38  ASP B O   1 
ATOM   2687 C CB  . ASP B 2 35  ? 96.783  122.740 161.557 1.00 127.58 ?  38  ASP B CB  1 
ATOM   2688 C CG  . ASP B 2 35  ? 97.074  123.723 162.669 1.00 130.78 ?  38  ASP B CG  1 
ATOM   2689 O OD1 . ASP B 2 35  ? 97.924  123.411 163.529 1.00 130.20 ?  38  ASP B OD1 1 
ATOM   2690 O OD2 . ASP B 2 35  ? 96.453  124.806 162.687 1.00 131.22 -1 38  ASP B OD2 1 
ATOM   2691 N N   . PRO B 2 36  ? 99.135  120.907 159.984 1.00 118.50 ?  39  PRO B N   1 
ATOM   2692 C CA  . PRO B 2 36  ? 100.472 120.947 159.384 1.00 119.20 ?  39  PRO B CA  1 
ATOM   2693 C C   . PRO B 2 36  ? 100.869 122.359 158.992 1.00 119.57 ?  39  PRO B C   1 
ATOM   2694 O O   . PRO B 2 36  ? 100.025 123.223 158.746 1.00 122.62 ?  39  PRO B O   1 
ATOM   2695 C CB  . PRO B 2 36  ? 100.337 120.046 158.152 1.00 120.63 ?  39  PRO B CB  1 
ATOM   2696 C CG  . PRO B 2 36  ? 98.882  120.054 157.838 1.00 118.94 ?  39  PRO B CG  1 
ATOM   2697 C CD  . PRO B 2 36  ? 98.175  120.164 159.152 1.00 116.46 ?  39  PRO B CD  1 
ATOM   2698 N N   . VAL B 2 37  ? 102.184 122.587 158.940 1.00 113.06 ?  40  VAL B N   1 
ATOM   2699 C CA  . VAL B 2 37  ? 102.701 123.902 158.582 1.00 114.41 ?  40  VAL B CA  1 
ATOM   2700 C C   . VAL B 2 37  ? 102.397 124.256 157.133 1.00 118.27 ?  40  VAL B C   1 
ATOM   2701 O O   . VAL B 2 37  ? 102.479 125.430 156.756 1.00 114.95 ?  40  VAL B O   1 
ATOM   2702 C CB  . VAL B 2 37  ? 104.216 123.978 158.845 1.00 114.08 ?  40  VAL B CB  1 
ATOM   2703 C CG1 . VAL B 2 37  ? 104.513 123.673 160.297 1.00 113.38 ?  40  VAL B CG1 1 
ATOM   2704 C CG2 . VAL B 2 37  ? 104.961 123.020 157.939 1.00 114.06 ?  40  VAL B CG2 1 
ATOM   2705 N N   . GLY B 2 38  ? 102.049 123.275 156.310 1.00 126.72 ?  41  GLY B N   1 
ATOM   2706 C CA  . GLY B 2 38  ? 101.744 123.535 154.922 1.00 126.76 ?  41  GLY B CA  1 
ATOM   2707 C C   . GLY B 2 38  ? 102.994 123.701 154.081 1.00 125.60 ?  41  GLY B C   1 
ATOM   2708 O O   . GLY B 2 38  ? 104.119 123.429 154.507 1.00 122.78 ?  41  GLY B O   1 
ATOM   2709 N N   . ARG B 2 39  ? 102.779 124.155 152.851 1.00 123.85 ?  42  ARG B N   1 
ATOM   2710 C CA  . ARG B 2 39  ? 103.891 124.381 151.941 1.00 122.86 ?  42  ARG B CA  1 
ATOM   2711 C C   . ARG B 2 39  ? 104.760 125.527 152.440 1.00 121.55 ?  42  ARG B C   1 
ATOM   2712 O O   . ARG B 2 39  ? 104.259 126.547 152.919 1.00 119.65 ?  42  ARG B O   1 
ATOM   2713 C CB  . ARG B 2 39  ? 103.378 124.682 150.535 1.00 122.37 ?  42  ARG B CB  1 
ATOM   2714 C CG  . ARG B 2 39  ? 104.300 124.202 149.426 1.00 121.89 ?  42  ARG B CG  1 
ATOM   2715 C CD  . ARG B 2 39  ? 104.572 122.711 149.534 1.00 124.03 ?  42  ARG B CD  1 
ATOM   2716 N NE  . ARG B 2 39  ? 105.648 122.286 148.646 1.00 128.81 ?  42  ARG B NE  1 
ATOM   2717 C CZ  . ARG B 2 39  ? 106.183 121.073 148.646 1.00 127.01 ?  42  ARG B CZ  1 
ATOM   2718 N NH1 . ARG B 2 39  ? 105.765 120.132 149.477 1.00 121.10 1  42  ARG B NH1 1 
ATOM   2719 N NH2 . ARG B 2 39  ? 107.160 120.795 147.788 1.00 124.19 ?  42  ARG B NH2 1 
ATOM   2720 N N   . ILE B 2 40  ? 106.072 125.349 152.327 1.00 116.00 ?  43  ILE B N   1 
ATOM   2721 C CA  . ILE B 2 40  ? 107.052 126.342 152.746 1.00 112.88 ?  43  ILE B CA  1 
ATOM   2722 C C   . ILE B 2 40  ? 107.670 126.938 151.491 1.00 113.84 ?  43  ILE B C   1 
ATOM   2723 O O   . ILE B 2 40  ? 108.249 126.214 150.672 1.00 113.18 ?  43  ILE B O   1 
ATOM   2724 C CB  . ILE B 2 40  ? 108.127 125.730 153.657 1.00 112.42 ?  43  ILE B CB  1 
ATOM   2725 C CG1 . ILE B 2 40  ? 107.554 125.435 155.043 1.00 111.25 ?  43  ILE B CG1 1 
ATOM   2726 C CG2 . ILE B 2 40  ? 109.316 126.652 153.766 1.00 107.33 ?  43  ILE B CG2 1 
ATOM   2727 C CD1 . ILE B 2 40  ? 107.070 126.655 155.774 1.00 108.21 ?  43  ILE B CD1 1 
ATOM   2728 N N   . GLN B 2 41  ? 107.544 128.252 151.338 1.00 124.44 ?  44  GLN B N   1 
ATOM   2729 C CA  . GLN B 2 41  ? 108.053 128.966 150.173 1.00 124.42 ?  44  GLN B CA  1 
ATOM   2730 C C   . GLN B 2 41  ? 109.295 129.749 150.576 1.00 123.91 ?  44  GLN B C   1 
ATOM   2731 O O   . GLN B 2 41  ? 109.199 130.757 151.283 1.00 124.52 ?  44  GLN B O   1 
ATOM   2732 C CB  . GLN B 2 41  ? 106.987 129.898 149.604 1.00 124.52 ?  44  GLN B CB  1 
ATOM   2733 C CG  . GLN B 2 41  ? 105.629 129.253 149.386 1.00 125.67 ?  44  GLN B CG  1 
ATOM   2734 C CD  . GLN B 2 41  ? 105.599 128.363 148.161 1.00 128.06 ?  44  GLN B CD  1 
ATOM   2735 O OE1 . GLN B 2 41  ? 105.301 128.820 147.058 1.00 127.88 ?  44  GLN B OE1 1 
ATOM   2736 N NE2 . GLN B 2 41  ? 105.901 127.086 148.347 1.00 123.68 ?  44  GLN B NE2 1 
ATOM   2737 N N   . MET B 2 42  ? 110.458 129.292 150.123 1.00 104.97 ?  45  MET B N   1 
ATOM   2738 C CA  . MET B 2 42  ? 111.703 130.023 150.293 1.00 103.30 ?  45  MET B CA  1 
ATOM   2739 C C   . MET B 2 42  ? 112.289 130.325 148.926 1.00 105.37 ?  45  MET B C   1 
ATOM   2740 O O   . MET B 2 42  ? 112.221 129.497 148.015 1.00 109.03 ?  45  MET B O   1 
ATOM   2741 C CB  . MET B 2 42  ? 112.726 129.246 151.128 1.00 104.03 ?  45  MET B CB  1 
ATOM   2742 C CG  . MET B 2 42  ? 112.174 128.554 152.357 1.00 107.78 ?  45  MET B CG  1 
ATOM   2743 S SD  . MET B 2 42  ? 113.287 128.764 153.755 1.00 113.44 ?  45  MET B SD  1 
ATOM   2744 C CE  . MET B 2 42  ? 112.368 127.957 155.056 1.00 106.69 ?  45  MET B CE  1 
ATOM   2745 N N   . ARG B 2 43  ? 112.862 131.516 148.790 1.00 101.05 ?  46  ARG B N   1 
ATOM   2746 C CA  . ARG B 2 43  ? 113.461 131.959 147.544 1.00 100.93 ?  46  ARG B CA  1 
ATOM   2747 C C   . ARG B 2 43  ? 114.887 132.413 147.806 1.00 98.40  ?  46  ARG B C   1 
ATOM   2748 O O   . ARG B 2 43  ? 115.215 132.875 148.899 1.00 108.96 ?  46  ARG B O   1 
ATOM   2749 C CB  . ARG B 2 43  ? 112.654 133.097 146.913 1.00 105.61 ?  46  ARG B CB  1 
ATOM   2750 C CG  . ARG B 2 43  ? 111.161 132.851 146.919 1.00 110.44 ?  46  ARG B CG  1 
ATOM   2751 C CD  . ARG B 2 43  ? 110.370 134.148 146.853 1.00 107.76 ?  46  ARG B CD  1 
ATOM   2752 N NE  . ARG B 2 43  ? 109.057 134.077 147.493 1.00 115.86 ?  46  ARG B NE  1 
ATOM   2753 C CZ  . ARG B 2 43  ? 108.140 133.136 147.293 1.00 117.98 ?  46  ARG B CZ  1 
ATOM   2754 N NH1 . ARG B 2 43  ? 108.298 132.186 146.385 1.00 109.62 1  46  ARG B NH1 1 
ATOM   2755 N NH2 . ARG B 2 43  ? 107.018 133.165 148.007 1.00 111.84 ?  46  ARG B NH2 1 
ATOM   2756 N N   . THR B 2 44  ? 115.730 132.275 146.793 1.00 78.17  ?  47  THR B N   1 
ATOM   2757 C CA  . THR B 2 44  ? 117.135 132.648 146.910 1.00 81.16  ?  47  THR B CA  1 
ATOM   2758 C C   . THR B 2 44  ? 117.239 134.164 146.977 1.00 87.99  ?  47  THR B C   1 
ATOM   2759 O O   . THR B 2 44  ? 117.163 134.852 145.958 1.00 93.35  ?  47  THR B O   1 
ATOM   2760 C CB  . THR B 2 44  ? 117.929 132.099 145.734 1.00 84.46  ?  47  THR B CB  1 
ATOM   2761 O OG1 . THR B 2 44  ? 117.762 130.680 145.667 1.00 90.53  ?  47  THR B OG1 1 
ATOM   2762 C CG2 . THR B 2 44  ? 119.396 132.417 145.898 1.00 79.32  ?  47  THR B CG2 1 
ATOM   2763 N N   . ARG B 2 45  ? 117.408 134.696 148.189 1.00 86.76  ?  48  ARG B N   1 
ATOM   2764 C CA  . ARG B 2 45  ? 117.549 136.138 148.346 1.00 77.12  ?  48  ARG B CA  1 
ATOM   2765 C C   . ARG B 2 45  ? 118.925 136.612 147.905 1.00 83.67  ?  48  ARG B C   1 
ATOM   2766 O O   . ARG B 2 45  ? 119.049 137.658 147.260 1.00 98.32  ?  48  ARG B O   1 
ATOM   2767 C CB  . ARG B 2 45  ? 117.288 136.534 149.795 1.00 76.80  ?  48  ARG B CB  1 
ATOM   2768 C CG  . ARG B 2 45  ? 115.927 136.131 150.301 1.00 80.63  ?  48  ARG B CG  1 
ATOM   2769 C CD  . ARG B 2 45  ? 114.844 136.507 149.317 1.00 87.39  ?  48  ARG B CD  1 
ATOM   2770 N NE  . ARG B 2 45  ? 113.543 135.995 149.722 1.00 91.81  ?  48  ARG B NE  1 
ATOM   2771 C CZ  . ARG B 2 45  ? 112.433 136.716 149.752 1.00 91.97  ?  48  ARG B CZ  1 
ATOM   2772 N NH1 . ARG B 2 45  ? 112.428 137.990 149.400 1.00 90.29  1  48  ARG B NH1 1 
ATOM   2773 N NH2 . ARG B 2 45  ? 111.299 136.145 150.144 1.00 87.53  ?  48  ARG B NH2 1 
ATOM   2774 N N   . ARG B 2 46  ? 119.969 135.866 148.246 1.00 76.62  ?  49  ARG B N   1 
ATOM   2775 C CA  . ARG B 2 46  ? 121.332 136.228 147.900 1.00 80.67  ?  49  ARG B CA  1 
ATOM   2776 C C   . ARG B 2 46  ? 122.049 135.017 147.328 1.00 81.55  ?  49  ARG B C   1 
ATOM   2777 O O   . ARG B 2 46  ? 121.708 133.874 147.633 1.00 90.17  ?  49  ARG B O   1 
ATOM   2778 C CB  . ARG B 2 46  ? 122.107 136.755 149.114 1.00 83.37  ?  49  ARG B CB  1 
ATOM   2779 C CG  . ARG B 2 46  ? 121.402 137.854 149.880 1.00 76.08  ?  49  ARG B CG  1 
ATOM   2780 C CD  . ARG B 2 46  ? 121.679 139.208 149.265 1.00 78.84  ?  49  ARG B CD  1 
ATOM   2781 N NE  . ARG B 2 46  ? 121.293 140.296 150.151 1.00 86.28  ?  49  ARG B NE  1 
ATOM   2782 C CZ  . ARG B 2 46  ? 120.082 140.831 150.192 1.00 89.27  ?  49  ARG B CZ  1 
ATOM   2783 N NH1 . ARG B 2 46  ? 119.112 140.404 149.403 1.00 85.63  1  49  ARG B NH1 1 
ATOM   2784 N NH2 . ARG B 2 46  ? 119.838 141.819 151.047 1.00 90.90  ?  49  ARG B NH2 1 
ATOM   2785 N N   . THR B 2 47  ? 123.046 135.280 146.490 1.00 69.82  ?  50  THR B N   1 
ATOM   2786 C CA  . THR B 2 47  ? 123.909 134.240 145.943 1.00 69.25  ?  50  THR B CA  1 
ATOM   2787 C C   . THR B 2 47  ? 125.348 134.708 146.081 1.00 69.74  ?  50  THR B C   1 
ATOM   2788 O O   . THR B 2 47  ? 125.782 135.609 145.359 1.00 78.34  ?  50  THR B O   1 
ATOM   2789 C CB  . THR B 2 47  ? 123.575 133.937 144.485 1.00 81.63  ?  50  THR B CB  1 
ATOM   2790 O OG1 . THR B 2 47  ? 122.213 133.508 144.385 1.00 91.50  ?  50  THR B OG1 1 
ATOM   2791 C CG2 . THR B 2 47  ? 124.482 132.842 143.954 1.00 73.64  ?  50  THR B CG2 1 
ATOM   2792 N N   . LEU B 2 48  ? 126.081 134.104 147.008 1.00 70.97  ?  51  LEU B N   1 
ATOM   2793 C CA  . LEU B 2 48  ? 127.472 134.462 147.233 1.00 76.44  ?  51  LEU B CA  1 
ATOM   2794 C C   . LEU B 2 48  ? 128.336 133.765 146.191 1.00 80.65  ?  51  LEU B C   1 
ATOM   2795 O O   . LEU B 2 48  ? 128.383 132.533 146.138 1.00 88.25  ?  51  LEU B O   1 
ATOM   2796 C CB  . LEU B 2 48  ? 127.882 134.086 148.652 1.00 75.47  ?  51  LEU B CB  1 
ATOM   2797 C CG  . LEU B 2 48  ? 126.844 134.460 149.711 1.00 77.41  ?  51  LEU B CG  1 
ATOM   2798 C CD1 . LEU B 2 48  ? 127.291 134.025 151.086 1.00 79.83  ?  51  LEU B CD1 1 
ATOM   2799 C CD2 . LEU B 2 48  ? 126.564 135.947 149.691 1.00 77.22  ?  51  LEU B CD2 1 
ATOM   2800 N N   . ARG B 2 49  ? 129.030 134.553 145.378 1.00 86.82  ?  52  ARG B N   1 
ATOM   2801 C CA  . ARG B 2 49  ? 129.565 134.114 144.095 1.00 90.00  ?  52  ARG B CA  1 
ATOM   2802 C C   . ARG B 2 49  ? 131.058 134.381 144.006 1.00 92.88  ?  52  ARG B C   1 
ATOM   2803 O O   . ARG B 2 49  ? 131.552 134.968 143.044 1.00 104.58 ?  52  ARG B O   1 
ATOM   2804 C CB  . ARG B 2 49  ? 128.823 134.805 142.956 1.00 94.64  ?  52  ARG B CB  1 
ATOM   2805 C CG  . ARG B 2 49  ? 128.762 134.006 141.674 1.00 100.17 ?  52  ARG B CG  1 
ATOM   2806 C CD  . ARG B 2 49  ? 128.038 134.765 140.581 1.00 95.75  ?  52  ARG B CD  1 
ATOM   2807 N NE  . ARG B 2 49  ? 126.608 134.485 140.567 1.00 97.17  ?  52  ARG B NE  1 
ATOM   2808 C CZ  . ARG B 2 49  ? 125.692 135.241 141.154 1.00 101.90 ?  52  ARG B CZ  1 
ATOM   2809 N NH1 . ARG B 2 49  ? 126.024 136.329 141.829 1.00 97.90  1  52  ARG B NH1 1 
ATOM   2810 N NH2 . ARG B 2 49  ? 124.411 134.898 141.062 1.00 96.25  ?  52  ARG B NH2 1 
ATOM   2811 N N   . GLY B 2 50  ? 131.805 133.961 145.019 1.00 77.22  ?  53  GLY B N   1 
ATOM   2812 C CA  . GLY B 2 50  ? 133.233 134.201 145.017 1.00 77.37  ?  53  GLY B CA  1 
ATOM   2813 C C   . GLY B 2 50  ? 134.109 132.969 144.947 1.00 78.35  ?  53  GLY B C   1 
ATOM   2814 O O   . GLY B 2 50  ? 135.221 133.029 144.420 1.00 86.99  ?  53  GLY B O   1 
ATOM   2815 N N   . HIS B 2 51  ? 133.630 131.848 145.477 1.00 80.06  ?  54  HIS B N   1 
ATOM   2816 C CA  . HIS B 2 51  ? 134.449 130.648 145.534 1.00 77.34  ?  54  HIS B CA  1 
ATOM   2817 C C   . HIS B 2 51  ? 134.639 130.060 144.140 1.00 81.66  ?  54  HIS B C   1 
ATOM   2818 O O   . HIS B 2 51  ? 133.882 130.339 143.208 1.00 87.98  ?  54  HIS B O   1 
ATOM   2819 C CB  . HIS B 2 51  ? 133.823 129.615 146.467 1.00 75.43  ?  54  HIS B CB  1 
ATOM   2820 C CG  . HIS B 2 51  ? 134.143 129.837 147.912 1.00 78.47  ?  54  HIS B CG  1 
ATOM   2821 N ND1 . HIS B 2 51  ? 135.434 129.912 148.385 1.00 76.81  ?  54  HIS B ND1 1 
ATOM   2822 C CD2 . HIS B 2 51  ? 133.340 130.006 148.987 1.00 76.94  ?  54  HIS B CD2 1 
ATOM   2823 C CE1 . HIS B 2 51  ? 135.413 130.116 149.688 1.00 72.95  ?  54  HIS B CE1 1 
ATOM   2824 N NE2 . HIS B 2 51  ? 134.154 130.177 150.079 1.00 74.34  ?  54  HIS B NE2 1 
ATOM   2825 N N   . LEU B 2 52  ? 135.677 129.234 144.004 1.00 86.43  ?  55  LEU B N   1 
ATOM   2826 C CA  . LEU B 2 52  ? 136.043 128.671 142.711 1.00 84.83  ?  55  LEU B CA  1 
ATOM   2827 C C   . LEU B 2 52  ? 136.113 127.150 142.721 1.00 88.83  ?  55  LEU B C   1 
ATOM   2828 O O   . LEU B 2 52  ? 136.494 126.556 141.707 1.00 101.06 ?  55  LEU B O   1 
ATOM   2829 C CB  . LEU B 2 52  ? 137.382 129.244 142.240 1.00 86.32  ?  55  LEU B CB  1 
ATOM   2830 C CG  . LEU B 2 52  ? 137.319 130.681 141.726 1.00 90.71  ?  55  LEU B CG  1 
ATOM   2831 C CD1 . LEU B 2 52  ? 138.694 131.165 141.338 1.00 89.92  ?  55  LEU B CD1 1 
ATOM   2832 C CD2 . LEU B 2 52  ? 136.361 130.781 140.555 1.00 83.12  ?  55  LEU B CD2 1 
ATOM   2833 N N   . ALA B 2 53  ? 135.754 126.505 143.824 1.00 84.79  ?  56  ALA B N   1 
ATOM   2834 C CA  . ALA B 2 53  ? 135.801 125.055 143.915 1.00 80.51  ?  56  ALA B CA  1 
ATOM   2835 C C   . ALA B 2 53  ? 134.665 124.598 144.819 1.00 82.41  ?  56  ALA B C   1 
ATOM   2836 O O   . ALA B 2 53  ? 133.768 125.373 145.158 1.00 85.14  ?  56  ALA B O   1 
ATOM   2837 C CB  . ALA B 2 53  ? 137.170 124.586 144.420 1.00 76.70  ?  56  ALA B CB  1 
ATOM   2838 N N   . LYS B 2 54  ? 134.705 123.331 145.212 1.00 85.70  ?  57  LYS B N   1 
ATOM   2839 C CA  . LYS B 2 54  ? 133.662 122.774 146.060 1.00 87.91  ?  57  LYS B CA  1 
ATOM   2840 C C   . LYS B 2 54  ? 133.662 123.466 147.414 1.00 89.17  ?  57  LYS B C   1 
ATOM   2841 O O   . LYS B 2 54  ? 134.718 123.669 148.016 1.00 91.25  ?  57  LYS B O   1 
ATOM   2842 C CB  . LYS B 2 54  ? 133.884 121.277 146.240 1.00 89.00  ?  57  LYS B CB  1 
ATOM   2843 C CG  . LYS B 2 54  ? 133.378 120.422 145.103 1.00 86.10  ?  57  LYS B CG  1 
ATOM   2844 C CD  . LYS B 2 54  ? 133.515 118.955 145.447 1.00 88.88  ?  57  LYS B CD  1 
ATOM   2845 C CE  . LYS B 2 54  ? 134.016 118.149 144.273 1.00 88.96  ?  57  LYS B CE  1 
ATOM   2846 N NZ  . LYS B 2 54  ? 134.549 116.834 144.717 1.00 92.14  1  57  LYS B NZ  1 
ATOM   2847 N N   . ILE B 2 55  ? 132.478 123.825 147.898 1.00 74.18  ?  58  ILE B N   1 
ATOM   2848 C CA  . ILE B 2 55  ? 132.326 124.397 149.230 1.00 73.73  ?  58  ILE B CA  1 
ATOM   2849 C C   . ILE B 2 55  ? 131.973 123.267 150.184 1.00 74.54  ?  58  ILE B C   1 
ATOM   2850 O O   . ILE B 2 55  ? 130.978 122.564 149.985 1.00 81.80  ?  58  ILE B O   1 
ATOM   2851 C CB  . ILE B 2 55  ? 131.254 125.495 149.251 1.00 70.43  ?  58  ILE B CB  1 
ATOM   2852 C CG1 . ILE B 2 55  ? 131.733 126.720 148.480 1.00 71.32  ?  58  ILE B CG1 1 
ATOM   2853 C CG2 . ILE B 2 55  ? 130.927 125.892 150.671 1.00 71.95  ?  58  ILE B CG2 1 
ATOM   2854 C CD1 . ILE B 2 55  ? 130.667 127.748 148.284 1.00 75.39  ?  58  ILE B CD1 1 
ATOM   2855 N N   . TYR B 2 56  ? 132.787 123.088 151.222 1.00 82.32  ?  59  TYR B N   1 
ATOM   2856 C CA  . TYR B 2 56  ? 132.615 121.966 152.131 1.00 79.90  ?  59  TYR B CA  1 
ATOM   2857 C C   . TYR B 2 56  ? 132.003 122.342 153.470 1.00 83.70  ?  59  TYR B C   1 
ATOM   2858 O O   . TYR B 2 56  ? 131.410 121.477 154.120 1.00 88.71  ?  59  TYR B O   1 
ATOM   2859 C CB  . TYR B 2 56  ? 133.957 121.266 152.367 1.00 80.34  ?  59  TYR B CB  1 
ATOM   2860 C CG  . TYR B 2 56  ? 134.221 120.169 151.371 1.00 84.51  ?  59  TYR B CG  1 
ATOM   2861 C CD1 . TYR B 2 56  ? 134.435 120.457 150.036 1.00 88.80  ?  59  TYR B CD1 1 
ATOM   2862 C CD2 . TYR B 2 56  ? 134.228 118.841 151.760 1.00 87.71  ?  59  TYR B CD2 1 
ATOM   2863 C CE1 . TYR B 2 56  ? 134.659 119.459 149.122 1.00 90.82  ?  59  TYR B CE1 1 
ATOM   2864 C CE2 . TYR B 2 56  ? 134.456 117.837 150.852 1.00 94.99  ?  59  TYR B CE2 1 
ATOM   2865 C CZ  . TYR B 2 56  ? 134.671 118.153 149.533 1.00 97.97  ?  59  TYR B CZ  1 
ATOM   2866 O OH  . TYR B 2 56  ? 134.898 117.156 148.616 1.00 101.01 ?  59  TYR B OH  1 
ATOM   2867 N N   . ALA B 2 57  ? 132.119 123.595 153.898 1.00 72.26  ?  60  ALA B N   1 
ATOM   2868 C CA  . ALA B 2 57  ? 131.581 123.984 155.190 1.00 72.78  ?  60  ALA B CA  1 
ATOM   2869 C C   . ALA B 2 57  ? 131.223 125.460 155.172 1.00 70.48  ?  60  ALA B C   1 
ATOM   2870 O O   . ALA B 2 57  ? 131.749 126.239 154.378 1.00 80.91  ?  60  ALA B O   1 
ATOM   2871 C CB  . ALA B 2 57  ? 132.572 123.688 156.317 1.00 75.61  ?  60  ALA B CB  1 
ATOM   2872 N N   . MET B 2 58  ? 130.311 125.829 156.064 1.00 80.88  ?  61  MET B N   1 
ATOM   2873 C CA  . MET B 2 58  ? 129.927 127.216 156.266 1.00 72.60  ?  61  MET B CA  1 
ATOM   2874 C C   . MET B 2 58  ? 129.359 127.349 157.668 1.00 79.24  ?  61  MET B C   1 
ATOM   2875 O O   . MET B 2 58  ? 128.792 126.399 158.211 1.00 89.99  ?  61  MET B O   1 
ATOM   2876 C CB  . MET B 2 58  ? 128.904 127.683 155.228 1.00 66.58  ?  61  MET B CB  1 
ATOM   2877 C CG  . MET B 2 58  ? 127.579 126.965 155.310 1.00 68.46  ?  61  MET B CG  1 
ATOM   2878 S SD  . MET B 2 58  ? 126.161 128.062 155.253 1.00 106.37 ?  61  MET B SD  1 
ATOM   2879 C CE  . MET B 2 58  ? 126.240 128.813 156.870 1.00 80.13  ?  61  MET B CE  1 
ATOM   2880 N N   . HIS B 2 59  ? 129.518 128.534 158.247 1.00 66.64  ?  62  HIS B N   1 
ATOM   2881 C CA  . HIS B 2 59  ? 129.008 128.784 159.587 1.00 61.53  ?  62  HIS B CA  1 
ATOM   2882 C C   . HIS B 2 59  ? 128.573 130.234 159.700 1.00 66.41  ?  62  HIS B C   1 
ATOM   2883 O O   . HIS B 2 59  ? 129.324 131.139 159.335 1.00 75.96  ?  62  HIS B O   1 
ATOM   2884 C CB  . HIS B 2 59  ? 130.062 128.461 160.646 1.00 63.34  ?  62  HIS B CB  1 
ATOM   2885 C CG  . HIS B 2 59  ? 129.491 128.219 162.006 1.00 63.92  ?  62  HIS B CG  1 
ATOM   2886 N ND1 . HIS B 2 59  ? 130.185 128.491 163.163 1.00 67.41  ?  62  HIS B ND1 1 
ATOM   2887 C CD2 . HIS B 2 59  ? 128.289 127.738 162.394 1.00 63.32  ?  62  HIS B CD2 1 
ATOM   2888 C CE1 . HIS B 2 59  ? 129.437 128.183 164.206 1.00 66.14  ?  62  HIS B CE1 1 
ATOM   2889 N NE2 . HIS B 2 59  ? 128.280 127.725 163.766 1.00 65.25  ?  62  HIS B NE2 1 
ATOM   2890 N N   . TRP B 2 60  ? 127.363 130.443 160.203 1.00 64.91  ?  63  TRP B N   1 
ATOM   2891 C CA  . TRP B 2 60  ? 126.858 131.782 160.450 1.00 67.70  ?  63  TRP B CA  1 
ATOM   2892 C C   . TRP B 2 60  ? 127.517 132.385 161.682 1.00 72.18  ?  63  TRP B C   1 
ATOM   2893 O O   . TRP B 2 60  ? 127.820 131.690 162.653 1.00 79.17  ?  63  TRP B O   1 
ATOM   2894 C CB  . TRP B 2 60  ? 125.345 131.756 160.660 1.00 57.61  ?  63  TRP B CB  1 
ATOM   2895 C CG  . TRP B 2 60  ? 124.532 131.728 159.415 1.00 64.89  ?  63  TRP B CG  1 
ATOM   2896 C CD1 . TRP B 2 60  ? 123.916 130.648 158.871 1.00 69.36  ?  63  TRP B CD1 1 
ATOM   2897 C CD2 . TRP B 2 60  ? 124.224 132.836 158.568 1.00 70.14  ?  63  TRP B CD2 1 
ATOM   2898 N NE1 . TRP B 2 60  ? 123.249 131.007 157.731 1.00 72.97  ?  63  TRP B NE1 1 
ATOM   2899 C CE2 . TRP B 2 60  ? 123.423 132.348 157.523 1.00 70.09  ?  63  TRP B CE2 1 
ATOM   2900 C CE3 . TRP B 2 60  ? 124.551 134.192 158.588 1.00 68.75  ?  63  TRP B CE3 1 
ATOM   2901 C CZ2 . TRP B 2 60  ? 122.943 133.167 156.510 1.00 63.10  ?  63  TRP B CZ2 1 
ATOM   2902 C CZ3 . TRP B 2 60  ? 124.076 134.999 157.583 1.00 70.48  ?  63  TRP B CZ3 1 
ATOM   2903 C CH2 . TRP B 2 60  ? 123.281 134.486 156.558 1.00 61.03  ?  63  TRP B CH2 1 
ATOM   2904 N N   . GLY B 2 61  ? 127.733 133.694 161.637 1.00 82.62  ?  64  GLY B N   1 
ATOM   2905 C CA  . GLY B 2 61  ? 128.107 134.408 162.835 1.00 72.71  ?  64  GLY B CA  1 
ATOM   2906 C C   . GLY B 2 61  ? 126.926 134.590 163.767 1.00 78.70  ?  64  GLY B C   1 
ATOM   2907 O O   . GLY B 2 61  ? 125.766 134.458 163.383 1.00 88.26  ?  64  GLY B O   1 
ATOM   2908 N N   . THR B 2 62  ? 127.230 134.897 165.027 1.00 81.66  ?  65  THR B N   1 
ATOM   2909 C CA  . THR B 2 62  ? 126.165 135.094 166.001 1.00 84.93  ?  65  THR B CA  1 
ATOM   2910 C C   . THR B 2 62  ? 125.364 136.360 165.737 1.00 93.35  ?  65  THR B C   1 
ATOM   2911 O O   . THR B 2 62  ? 124.262 136.504 166.273 1.00 97.01  ?  65  THR B O   1 
ATOM   2912 C CB  . THR B 2 62  ? 126.741 135.127 167.414 1.00 88.79  ?  65  THR B CB  1 
ATOM   2913 O OG1 . THR B 2 62  ? 128.020 135.769 167.394 1.00 98.64  ?  65  THR B OG1 1 
ATOM   2914 C CG2 . THR B 2 62  ? 126.896 133.719 167.948 1.00 86.32  ?  65  THR B CG2 1 
ATOM   2915 N N   . ASP B 2 63  ? 125.885 137.272 164.922 1.00 87.77  ?  66  ASP B N   1 
ATOM   2916 C CA  . ASP B 2 63  ? 125.161 138.480 164.554 1.00 77.81  ?  66  ASP B CA  1 
ATOM   2917 C C   . ASP B 2 63  ? 124.143 138.241 163.451 1.00 78.12  ?  66  ASP B C   1 
ATOM   2918 O O   . ASP B 2 63  ? 123.405 139.169 163.105 1.00 88.63  ?  66  ASP B O   1 
ATOM   2919 C CB  . ASP B 2 63  ? 126.142 139.569 164.120 1.00 91.47  ?  66  ASP B CB  1 
ATOM   2920 C CG  . ASP B 2 63  ? 127.202 139.051 163.172 1.00 97.74  ?  66  ASP B CG  1 
ATOM   2921 O OD1 . ASP B 2 63  ? 126.862 138.733 162.016 1.00 97.91  ?  66  ASP B OD1 1 
ATOM   2922 O OD2 . ASP B 2 63  ? 128.376 138.957 163.585 1.00 101.32 -1 66  ASP B OD2 1 
ATOM   2923 N N   . SER B 2 64  ? 124.098 137.034 162.889 1.00 68.48  ?  67  SER B N   1 
ATOM   2924 C CA  . SER B 2 64  ? 123.160 136.651 161.838 1.00 73.43  ?  67  SER B CA  1 
ATOM   2925 C C   . SER B 2 64  ? 123.346 137.466 160.569 1.00 74.86  ?  67  SER B C   1 
ATOM   2926 O O   . SER B 2 64  ? 122.431 137.562 159.750 1.00 82.33  ?  67  SER B O   1 
ATOM   2927 C CB  . SER B 2 64  ? 121.711 136.753 162.321 1.00 80.35  ?  67  SER B CB  1 
ATOM   2928 O OG  . SER B 2 64  ? 121.575 136.225 163.626 1.00 86.44  ?  67  SER B OG  1 
ATOM   2929 N N   . ARG B 2 65  ? 124.505 138.056 160.392 1.00 69.93  ?  68  ARG B N   1 
ATOM   2930 C CA  . ARG B 2 65  ? 124.805 138.805 159.181 1.00 69.20  ?  68  ARG B CA  1 
ATOM   2931 C C   . ARG B 2 65  ? 126.095 138.356 158.518 1.00 70.76  ?  68  ARG B C   1 
ATOM   2932 O O   . ARG B 2 65  ? 126.156 138.288 157.290 1.00 74.43  ?  68  ARG B O   1 
ATOM   2933 C CB  . ARG B 2 65  ? 124.877 140.303 159.498 1.00 76.83  ?  68  ARG B CB  1 
ATOM   2934 C CG  . ARG B 2 65  ? 125.395 141.140 158.357 1.00 72.13  ?  68  ARG B CG  1 
ATOM   2935 C CD  . ARG B 2 65  ? 125.080 142.600 158.547 1.00 71.27  ?  68  ARG B CD  1 
ATOM   2936 N NE  . ARG B 2 65  ? 125.522 143.388 157.405 1.00 76.29  ?  68  ARG B NE  1 
ATOM   2937 C CZ  . ARG B 2 65  ? 125.124 144.626 157.154 1.00 69.69  ?  68  ARG B CZ  1 
ATOM   2938 N NH1 . ARG B 2 65  ? 124.275 145.251 157.949 1.00 69.98  1  68  ARG B NH1 1 
ATOM   2939 N NH2 . ARG B 2 65  ? 125.590 145.250 156.078 1.00 71.73  ?  68  ARG B NH2 1 
ATOM   2940 N N   . LEU B 2 66  ? 127.118 138.030 159.296 1.00 66.44  ?  69  LEU B N   1 
ATOM   2941 C CA  . LEU B 2 66  ? 128.389 137.567 158.767 1.00 61.05  ?  69  LEU B CA  1 
ATOM   2942 C C   . LEU B 2 66  ? 128.424 136.048 158.784 1.00 73.39  ?  69  LEU B C   1 
ATOM   2943 O O   . LEU B 2 66  ? 127.963 135.417 159.738 1.00 78.72  ?  69  LEU B O   1 
ATOM   2944 C CB  . LEU B 2 66  ? 129.558 138.120 159.580 1.00 62.86  ?  69  LEU B CB  1 
ATOM   2945 C CG  . LEU B 2 66  ? 129.848 139.616 159.498 1.00 70.43  ?  69  LEU B CG  1 
ATOM   2946 C CD1 . LEU B 2 66  ? 131.034 139.962 160.365 1.00 68.88  ?  69  LEU B CD1 1 
ATOM   2947 C CD2 . LEU B 2 66  ? 130.102 140.031 158.071 1.00 69.82  ?  69  LEU B CD2 1 
ATOM   2948 N N   . LEU B 2 67  ? 128.958 135.463 157.718 1.00 63.64  ?  70  LEU B N   1 
ATOM   2949 C CA  . LEU B 2 67  ? 129.135 134.024 157.647 1.00 63.73  ?  70  LEU B CA  1 
ATOM   2950 C C   . LEU B 2 67  ? 130.477 133.723 157.005 1.00 58.52  ?  70  LEU B C   1 
ATOM   2951 O O   . LEU B 2 67  ? 130.959 134.475 156.158 1.00 67.28  ?  70  LEU B O   1 
ATOM   2952 C CB  . LEU B 2 67  ? 127.996 133.351 156.870 1.00 67.09  ?  70  LEU B CB  1 
ATOM   2953 C CG  . LEU B 2 67  ? 127.889 133.576 155.365 1.00 67.11  ?  70  LEU B CG  1 
ATOM   2954 C CD1 . LEU B 2 67  ? 128.423 132.382 154.605 1.00 72.31  ?  70  LEU B CD1 1 
ATOM   2955 C CD2 . LEU B 2 67  ? 126.457 133.844 154.984 1.00 67.93  ?  70  LEU B CD2 1 
ATOM   2956 N N   . VAL B 2 68  ? 131.079 132.618 157.423 1.00 64.25  ?  71  VAL B N   1 
ATOM   2957 C CA  . VAL B 2 68  ? 132.360 132.168 156.901 1.00 61.98  ?  71  VAL B CA  1 
ATOM   2958 C C   . VAL B 2 68  ? 132.128 130.876 156.137 1.00 69.50  ?  71  VAL B C   1 
ATOM   2959 O O   . VAL B 2 68  ? 131.331 130.031 156.556 1.00 87.99  ?  71  VAL B O   1 
ATOM   2960 C CB  . VAL B 2 68  ? 133.397 131.982 158.026 1.00 54.16  ?  71  VAL B CB  1 
ATOM   2961 C CG1 . VAL B 2 68  ? 132.910 130.981 159.050 1.00 46.10  ?  71  VAL B CG1 1 
ATOM   2962 C CG2 . VAL B 2 68  ? 134.737 131.575 157.459 1.00 62.22  ?  71  VAL B CG2 1 
ATOM   2963 N N   . SER B 2 69  ? 132.790 130.740 154.995 1.00 60.12  ?  72  SER B N   1 
ATOM   2964 C CA  . SER B 2 69  ? 132.654 129.561 154.157 1.00 56.10  ?  72  SER B CA  1 
ATOM   2965 C C   . SER B 2 69  ? 134.031 129.048 153.779 1.00 64.24  ?  72  SER B C   1 
ATOM   2966 O O   . SER B 2 69  ? 134.938 129.832 153.497 1.00 73.00  ?  72  SER B O   1 
ATOM   2967 C CB  . SER B 2 69  ? 131.844 129.865 152.901 1.00 53.98  ?  72  SER B CB  1 
ATOM   2968 O OG  . SER B 2 69  ? 132.666 130.418 151.896 1.00 65.84  ?  72  SER B OG  1 
ATOM   2969 N N   . ALA B 2 70  ? 134.182 127.730 153.784 1.00 72.47  ?  73  ALA B N   1 
ATOM   2970 C CA  . ALA B 2 70  ? 135.434 127.071 153.446 1.00 58.30  ?  73  ALA B CA  1 
ATOM   2971 C C   . ALA B 2 70  ? 135.242 126.265 152.174 1.00 65.82  ?  73  ALA B C   1 
ATOM   2972 O O   . ALA B 2 70  ? 134.278 125.505 152.058 1.00 75.05  ?  73  ALA B O   1 
ATOM   2973 C CB  . ALA B 2 70  ? 135.901 126.160 154.579 1.00 61.77  ?  73  ALA B CB  1 
ATOM   2974 N N   . SER B 2 71  ? 136.154 126.430 151.226 1.00 70.24  ?  74  SER B N   1 
ATOM   2975 C CA  . SER B 2 71  ? 136.085 125.710 149.968 1.00 81.29  ?  74  SER B CA  1 
ATOM   2976 C C   . SER B 2 71  ? 137.433 125.071 149.679 1.00 82.07  ?  74  SER B C   1 
ATOM   2977 O O   . SER B 2 71  ? 138.431 125.331 150.354 1.00 79.87  ?  74  SER B O   1 
ATOM   2978 C CB  . SER B 2 71  ? 135.668 126.627 148.817 1.00 80.65  ?  74  SER B CB  1 
ATOM   2979 O OG  . SER B 2 71  ? 136.753 126.864 147.952 1.00 86.84  ?  74  SER B OG  1 
ATOM   2980 N N   . GLN B 2 72  ? 137.454 124.224 148.655 1.00 90.47  ?  75  GLN B N   1 
ATOM   2981 C CA  . GLN B 2 72  ? 138.628 123.417 148.360 1.00 87.65  ?  75  GLN B CA  1 
ATOM   2982 C C   . GLN B 2 72  ? 139.675 124.152 147.538 1.00 92.38  ?  75  GLN B C   1 
ATOM   2983 O O   . GLN B 2 72  ? 140.715 123.561 147.232 1.00 94.98  ?  75  GLN B O   1 
ATOM   2984 C CB  . GLN B 2 72  ? 138.218 122.134 147.641 1.00 96.34  ?  75  GLN B CB  1 
ATOM   2985 C CG  . GLN B 2 72  ? 137.595 121.091 148.552 1.00 98.60  ?  75  GLN B CG  1 
ATOM   2986 C CD  . GLN B 2 72  ? 138.605 120.411 149.451 1.00 99.92  ?  75  GLN B CD  1 
ATOM   2987 O OE1 . GLN B 2 72  ? 139.803 120.655 149.351 1.00 103.57 ?  75  GLN B OE1 1 
ATOM   2988 N NE2 . GLN B 2 72  ? 138.124 119.549 150.335 1.00 92.57  ?  75  GLN B NE2 1 
ATOM   2989 N N   . ASP B 2 73  ? 139.440 125.408 147.165 1.00 91.59  ?  76  ASP B N   1 
ATOM   2990 C CA  . ASP B 2 73  ? 140.499 126.213 146.575 1.00 88.83  ?  76  ASP B CA  1 
ATOM   2991 C C   . ASP B 2 73  ? 141.416 126.817 147.624 1.00 86.70  ?  76  ASP B C   1 
ATOM   2992 O O   . ASP B 2 73  ? 142.165 127.750 147.317 1.00 95.46  ?  76  ASP B O   1 
ATOM   2993 C CB  . ASP B 2 73  ? 139.916 127.316 145.686 1.00 89.92  ?  76  ASP B CB  1 
ATOM   2994 C CG  . ASP B 2 73  ? 138.791 128.076 146.349 1.00 97.02  ?  76  ASP B CG  1 
ATOM   2995 O OD1 . ASP B 2 73  ? 138.720 128.082 147.591 1.00 101.13 ?  76  ASP B OD1 1 
ATOM   2996 O OD2 . ASP B 2 73  ? 137.967 128.672 145.627 1.00 98.38  -1 76  ASP B OD2 1 
ATOM   2997 N N   . GLY B 2 74  ? 141.370 126.301 148.847 1.00 71.98  ?  77  GLY B N   1 
ATOM   2998 C CA  . GLY B 2 74  ? 142.220 126.780 149.918 1.00 80.62  ?  77  GLY B CA  1 
ATOM   2999 C C   . GLY B 2 74  ? 141.941 128.204 150.333 1.00 85.25  ?  77  GLY B C   1 
ATOM   3000 O O   . GLY B 2 74  ? 142.879 128.954 150.624 1.00 88.46  ?  77  GLY B O   1 
ATOM   3001 N N   . LYS B 2 75  ? 140.673 128.597 150.376 1.00 78.30  ?  78  LYS B N   1 
ATOM   3002 C CA  . LYS B 2 75  ? 140.300 129.964 150.702 1.00 72.63  ?  78  LYS B CA  1 
ATOM   3003 C C   . LYS B 2 75  ? 139.176 129.969 151.724 1.00 69.90  ?  78  LYS B C   1 
ATOM   3004 O O   . LYS B 2 75  ? 138.173 129.272 151.555 1.00 80.16  ?  78  LYS B O   1 
ATOM   3005 C CB  . LYS B 2 75  ? 139.880 130.729 149.446 1.00 69.20  ?  78  LYS B CB  1 
ATOM   3006 C CG  . LYS B 2 75  ? 140.326 132.173 149.441 1.00 76.82  ?  78  LYS B CG  1 
ATOM   3007 C CD  . LYS B 2 75  ? 141.817 132.299 149.192 1.00 81.11  ?  78  LYS B CD  1 
ATOM   3008 C CE  . LYS B 2 75  ? 142.173 131.929 147.769 1.00 82.28  ?  78  LYS B CE  1 
ATOM   3009 N NZ  . LYS B 2 75  ? 143.540 131.357 147.676 1.00 82.24  1  78  LYS B NZ  1 
ATOM   3010 N N   . LEU B 2 76  ? 139.354 130.754 152.781 1.00 69.51  ?  79  LEU B N   1 
ATOM   3011 C CA  . LEU B 2 76  ? 138.309 131.039 153.754 1.00 60.22  ?  79  LEU B CA  1 
ATOM   3012 C C   . LEU B 2 76  ? 137.783 132.439 153.478 1.00 68.95  ?  79  LEU B C   1 
ATOM   3013 O O   . LEU B 2 76  ? 138.540 133.411 153.550 1.00 89.48  ?  79  LEU B O   1 
ATOM   3014 C CB  . LEU B 2 76  ? 138.853 130.955 155.179 1.00 61.85  ?  79  LEU B CB  1 
ATOM   3015 C CG  . LEU B 2 76  ? 138.575 129.730 156.038 1.00 64.47  ?  79  LEU B CG  1 
ATOM   3016 C CD1 . LEU B 2 76  ? 138.868 130.048 157.486 1.00 65.23  ?  79  LEU B CD1 1 
ATOM   3017 C CD2 . LEU B 2 76  ? 137.151 129.302 155.870 1.00 69.79  ?  79  LEU B CD2 1 
ATOM   3018 N N   . ILE B 2 77  ? 136.497 132.548 153.169 1.00 53.16  ?  80  ILE B N   1 
ATOM   3019 C CA  . ILE B 2 77  ? 135.884 133.823 152.823 1.00 64.07  ?  80  ILE B CA  1 
ATOM   3020 C C   . ILE B 2 77  ? 134.826 134.153 153.861 1.00 67.41  ?  80  ILE B C   1 
ATOM   3021 O O   . ILE B 2 77  ? 134.002 133.301 154.207 1.00 78.51  ?  80  ILE B O   1 
ATOM   3022 C CB  . ILE B 2 77  ? 135.275 133.803 151.411 1.00 59.16  ?  80  ILE B CB  1 
ATOM   3023 C CG1 . ILE B 2 77  ? 136.352 133.516 150.371 1.00 60.93  ?  80  ILE B CG1 1 
ATOM   3024 C CG2 . ILE B 2 77  ? 134.607 135.125 151.106 1.00 58.87  ?  80  ILE B CG2 1 
ATOM   3025 C CD1 . ILE B 2 77  ? 135.852 133.597 148.961 1.00 69.20  ?  80  ILE B CD1 1 
ATOM   3026 N N   . ILE B 2 78  ? 134.854 135.384 154.359 1.00 62.44  ?  81  ILE B N   1 
ATOM   3027 C CA  . ILE B 2 78  ? 133.853 135.893 155.285 1.00 53.61  ?  81  ILE B CA  1 
ATOM   3028 C C   . ILE B 2 78  ? 132.960 136.851 154.514 1.00 59.21  ?  81  ILE B C   1 
ATOM   3029 O O   . ILE B 2 78  ? 133.439 137.840 153.951 1.00 77.60  ?  81  ILE B O   1 
ATOM   3030 C CB  . ILE B 2 78  ? 134.503 136.578 156.492 1.00 54.07  ?  81  ILE B CB  1 
ATOM   3031 C CG1 . ILE B 2 78  ? 135.294 135.550 157.291 1.00 57.74  ?  81  ILE B CG1 1 
ATOM   3032 C CG2 . ILE B 2 78  ? 133.457 137.229 157.363 1.00 54.26  ?  81  ILE B CG2 1 
ATOM   3033 C CD1 . ILE B 2 78  ? 135.951 136.114 158.487 1.00 61.57  ?  81  ILE B CD1 1 
ATOM   3034 N N   . TRP B 2 79  ? 131.668 136.555 154.483 1.00 59.69  ?  82  TRP B N   1 
ATOM   3035 C CA  . TRP B 2 79  ? 130.712 137.285 153.669 1.00 56.21  ?  82  TRP B CA  1 
ATOM   3036 C C   . TRP B 2 79  ? 129.857 138.194 154.534 1.00 65.71  ?  82  TRP B C   1 
ATOM   3037 O O   . TRP B 2 79  ? 129.480 137.833 155.650 1.00 83.24  ?  82  TRP B O   1 
ATOM   3038 C CB  . TRP B 2 79  ? 129.794 136.334 152.903 1.00 67.26  ?  82  TRP B CB  1 
ATOM   3039 C CG  . TRP B 2 79  ? 130.497 135.262 152.162 1.00 75.83  ?  82  TRP B CG  1 
ATOM   3040 C CD1 . TRP B 2 79  ? 130.980 134.099 152.670 1.00 73.07  ?  82  TRP B CD1 1 
ATOM   3041 C CD2 . TRP B 2 79  ? 130.784 135.242 150.765 1.00 74.84  ?  82  TRP B CD2 1 
ATOM   3042 N NE1 . TRP B 2 79  ? 131.560 133.355 151.678 1.00 67.22  ?  82  TRP B NE1 1 
ATOM   3043 C CE2 . TRP B 2 79  ? 131.450 134.036 150.496 1.00 71.18  ?  82  TRP B CE2 1 
ATOM   3044 C CE3 . TRP B 2 79  ? 130.544 136.129 149.715 1.00 60.88  ?  82  TRP B CE3 1 
ATOM   3045 C CZ2 . TRP B 2 79  ? 131.882 133.694 149.223 1.00 67.47  ?  82  TRP B CZ2 1 
ATOM   3046 C CZ3 . TRP B 2 79  ? 130.972 135.788 148.457 1.00 67.90  ?  82  TRP B CZ3 1 
ATOM   3047 C CH2 . TRP B 2 79  ? 131.633 134.582 148.219 1.00 71.38  ?  82  TRP B CH2 1 
ATOM   3048 N N   . ASP B 2 80  ? 129.550 139.372 154.007 1.00 74.43  ?  83  ASP B N   1 
ATOM   3049 C CA  . ASP B 2 80  ? 128.482 140.207 154.542 1.00 69.46  ?  83  ASP B CA  1 
ATOM   3050 C C   . ASP B 2 80  ? 127.222 139.817 153.784 1.00 71.86  ?  83  ASP B C   1 
ATOM   3051 O O   . ASP B 2 80  ? 126.990 140.278 152.667 1.00 85.88  ?  83  ASP B O   1 
ATOM   3052 C CB  . ASP B 2 80  ? 128.817 141.683 154.386 1.00 69.51  ?  83  ASP B CB  1 
ATOM   3053 C CG  . ASP B 2 80  ? 127.738 142.583 154.927 1.00 78.57  ?  83  ASP B CG  1 
ATOM   3054 O OD1 . ASP B 2 80  ? 126.923 142.111 155.740 1.00 78.50  ?  83  ASP B OD1 1 
ATOM   3055 O OD2 . ASP B 2 80  ? 127.707 143.768 154.545 1.00 78.92  -1 83  ASP B OD2 1 
ATOM   3056 N N   . SER B 2 81  ? 126.415 138.942 154.384 1.00 64.08  ?  84  SER B N   1 
ATOM   3057 C CA  . SER B 2 81  ? 125.302 138.345 153.654 1.00 61.05  ?  84  SER B CA  1 
ATOM   3058 C C   . SER B 2 81  ? 124.277 139.382 153.224 1.00 77.47  ?  84  SER B C   1 
ATOM   3059 O O   . SER B 2 81  ? 123.590 139.188 152.216 1.00 93.87  ?  84  SER B O   1 
ATOM   3060 C CB  . SER B 2 81  ? 124.639 137.269 154.507 1.00 69.65  ?  84  SER B CB  1 
ATOM   3061 O OG  . SER B 2 81  ? 124.493 137.712 155.841 1.00 77.80  ?  84  SER B OG  1 
ATOM   3062 N N   . TYR B 2 82  ? 124.150 140.480 153.970 1.00 73.40  ?  85  TYR B N   1 
ATOM   3063 C CA  . TYR B 2 82  ? 123.170 141.500 153.615 1.00 65.38  ?  85  TYR B CA  1 
ATOM   3064 C C   . TYR B 2 82  ? 123.508 142.145 152.279 1.00 75.26  ?  85  TYR B C   1 
ATOM   3065 O O   . TYR B 2 82  ? 122.616 142.407 151.464 1.00 82.18  ?  85  TYR B O   1 
ATOM   3066 C CB  . TYR B 2 82  ? 123.093 142.563 154.706 1.00 67.52  ?  85  TYR B CB  1 
ATOM   3067 C CG  . TYR B 2 82  ? 122.346 142.148 155.950 1.00 72.58  ?  85  TYR B CG  1 
ATOM   3068 C CD1 . TYR B 2 82  ? 122.162 140.814 156.265 1.00 76.84  ?  85  TYR B CD1 1 
ATOM   3069 C CD2 . TYR B 2 82  ? 121.833 143.098 156.815 1.00 77.66  ?  85  TYR B CD2 1 
ATOM   3070 C CE1 . TYR B 2 82  ? 121.488 140.439 157.402 1.00 79.94  ?  85  TYR B CE1 1 
ATOM   3071 C CE2 . TYR B 2 82  ? 121.157 142.731 157.953 1.00 77.66  ?  85  TYR B CE2 1 
ATOM   3072 C CZ  . TYR B 2 82  ? 120.989 141.402 158.243 1.00 82.18  ?  85  TYR B CZ  1 
ATOM   3073 O OH  . TYR B 2 82  ? 120.312 141.033 159.379 1.00 87.99  ?  85  TYR B OH  1 
ATOM   3074 N N   . THR B 2 83  ? 124.789 142.413 152.038 1.00 73.76  ?  86  THR B N   1 
ATOM   3075 C CA  . THR B 2 83  ? 125.236 143.108 150.841 1.00 63.16  ?  86  THR B CA  1 
ATOM   3076 C C   . THR B 2 83  ? 126.095 142.247 149.927 1.00 68.72  ?  86  THR B C   1 
ATOM   3077 O O   . THR B 2 83  ? 126.582 142.751 148.911 1.00 78.28  ?  86  THR B O   1 
ATOM   3078 C CB  . THR B 2 83  ? 126.020 144.366 151.226 1.00 70.18  ?  86  THR B CB  1 
ATOM   3079 O OG1 . THR B 2 83  ? 127.354 144.000 151.593 1.00 66.42  ?  86  THR B OG1 1 
ATOM   3080 C CG2 . THR B 2 83  ? 125.363 145.066 152.395 1.00 63.57  ?  86  THR B CG2 1 
ATOM   3081 N N   . THR B 2 84  ? 126.297 140.972 150.258 1.00 79.17  ?  87  THR B N   1 
ATOM   3082 C CA  . THR B 2 84  ? 127.152 140.055 149.504 1.00 74.51  ?  87  THR B CA  1 
ATOM   3083 C C   . THR B 2 84  ? 128.585 140.556 149.387 1.00 72.52  ?  87  THR B C   1 
ATOM   3084 O O   . THR B 2 84  ? 129.303 140.175 148.459 1.00 79.00  ?  87  THR B O   1 
ATOM   3085 C CB  . THR B 2 84  ? 126.587 139.768 148.108 1.00 86.52  ?  87  THR B CB  1 
ATOM   3086 O OG1 . THR B 2 84  ? 126.767 140.917 147.273 1.00 85.25  ?  87  THR B OG1 1 
ATOM   3087 C CG2 . THR B 2 84  ? 125.111 139.428 148.187 1.00 79.59  ?  87  THR B CG2 1 
ATOM   3088 N N   . ASN B 2 85  ? 129.020 141.403 150.312 1.00 66.35  ?  88  ASN B N   1 
ATOM   3089 C CA  . ASN B 2 85  ? 130.391 141.885 150.319 1.00 68.70  ?  88  ASN B CA  1 
ATOM   3090 C C   . ASN B 2 85  ? 131.314 140.851 150.946 1.00 67.71  ?  88  ASN B C   1 
ATOM   3091 O O   . ASN B 2 85  ? 130.921 140.097 151.837 1.00 82.14  ?  88  ASN B O   1 
ATOM   3092 C CB  . ASN B 2 85  ? 130.497 143.197 151.096 1.00 75.36  ?  88  ASN B CB  1 
ATOM   3093 C CG  . ASN B 2 85  ? 130.265 144.410 150.230 1.00 74.05  ?  88  ASN B CG  1 
ATOM   3094 O OD1 . ASN B 2 85  ? 130.395 144.351 149.011 1.00 74.25  ?  88  ASN B OD1 1 
ATOM   3095 N ND2 . ASN B 2 85  ? 129.916 145.521 150.858 1.00 77.11  ?  88  ASN B ND2 1 
ATOM   3096 N N   . LYS B 2 86  ? 132.553 140.825 150.478 1.00 56.19  ?  89  LYS B N   1 
ATOM   3097 C CA  . LYS B 2 86  ? 133.576 139.942 151.025 1.00 62.36  ?  89  LYS B CA  1 
ATOM   3098 C C   . LYS B 2 86  ? 134.366 140.731 152.059 1.00 71.93  ?  89  LYS B C   1 
ATOM   3099 O O   . LYS B 2 86  ? 135.193 141.576 151.711 1.00 78.08  ?  89  LYS B O   1 
ATOM   3100 C CB  . LYS B 2 86  ? 134.481 139.411 149.923 1.00 70.56  ?  89  LYS B CB  1 
ATOM   3101 C CG  . LYS B 2 86  ? 133.763 138.579 148.900 1.00 67.37  ?  89  LYS B CG  1 
ATOM   3102 C CD  . LYS B 2 86  ? 134.737 137.763 148.097 1.00 60.07  ?  89  LYS B CD  1 
ATOM   3103 C CE  . LYS B 2 86  ? 134.019 136.989 147.023 1.00 70.06  ?  89  LYS B CE  1 
ATOM   3104 N NZ  . LYS B 2 86  ? 133.047 137.839 146.293 1.00 66.47  1  89  LYS B NZ  1 
ATOM   3105 N N   . VAL B 2 87  ? 134.103 140.461 153.335 1.00 59.40  ?  90  VAL B N   1 
ATOM   3106 C CA  . VAL B 2 87  ? 134.818 141.158 154.397 1.00 46.31  ?  90  VAL B CA  1 
ATOM   3107 C C   . VAL B 2 87  ? 136.275 140.723 154.429 1.00 45.75  ?  90  VAL B C   1 
ATOM   3108 O O   . VAL B 2 87  ? 137.187 141.554 154.488 1.00 68.46  ?  90  VAL B O   1 
ATOM   3109 C CB  . VAL B 2 87  ? 134.124 140.923 155.748 1.00 49.43  ?  90  VAL B CB  1 
ATOM   3110 C CG1 . VAL B 2 87  ? 134.675 141.857 156.793 1.00 54.03  ?  90  VAL B CG1 1 
ATOM   3111 C CG2 . VAL B 2 87  ? 132.634 141.111 155.603 1.00 51.58  ?  90  VAL B CG2 1 
ATOM   3112 N N   . HIS B 2 88  ? 136.517 139.417 154.380 1.00 60.36  ?  91  HIS B N   1 
ATOM   3113 C CA  . HIS B 2 88  ? 137.862 138.870 154.433 1.00 61.21  ?  91  HIS B CA  1 
ATOM   3114 C C   . HIS B 2 88  ? 137.970 137.711 153.457 1.00 67.33  ?  91  HIS B C   1 
ATOM   3115 O O   . HIS B 2 88  ? 136.975 137.085 153.091 1.00 76.54  ?  91  HIS B O   1 
ATOM   3116 C CB  . HIS B 2 88  ? 138.230 138.385 155.840 1.00 58.67  ?  91  HIS B CB  1 
ATOM   3117 C CG  . HIS B 2 88  ? 138.447 139.487 156.828 1.00 67.97  ?  91  HIS B CG  1 
ATOM   3118 N ND1 . HIS B 2 88  ? 137.559 139.758 157.844 1.00 71.89  ?  91  HIS B ND1 1 
ATOM   3119 C CD2 . HIS B 2 88  ? 139.457 140.377 156.964 1.00 65.05  ?  91  HIS B CD2 1 
ATOM   3120 C CE1 . HIS B 2 88  ? 138.008 140.772 158.560 1.00 66.41  ?  91  HIS B CE1 1 
ATOM   3121 N NE2 . HIS B 2 88  ? 139.159 141.166 158.047 1.00 71.07  ?  91  HIS B NE2 1 
ATOM   3122 N N   . ALA B 2 89  ? 139.201 137.431 153.041 1.00 70.78  ?  92  ALA B N   1 
ATOM   3123 C CA  . ALA B 2 89  ? 139.515 136.245 152.251 1.00 57.90  ?  92  ALA B CA  1 
ATOM   3124 C C   . ALA B 2 89  ? 140.822 135.687 152.789 1.00 67.18  ?  92  ALA B C   1 
ATOM   3125 O O   . ALA B 2 89  ? 141.885 136.269 152.560 1.00 84.73  ?  92  ALA B O   1 
ATOM   3126 C CB  . ALA B 2 89  ? 139.622 136.568 150.764 1.00 60.18  ?  92  ALA B CB  1 
ATOM   3127 N N   . ILE B 2 90  ? 140.744 134.575 153.507 1.00 66.02  ?  93  ILE B N   1 
ATOM   3128 C CA  . ILE B 2 90  ? 141.883 134.009 154.223 1.00 77.45  ?  93  ILE B CA  1 
ATOM   3129 C C   . ILE B 2 90  ? 142.465 132.879 153.382 1.00 77.28  ?  93  ILE B C   1 
ATOM   3130 O O   . ILE B 2 90  ? 141.767 131.884 153.139 1.00 82.59  ?  93  ILE B O   1 
ATOM   3131 C CB  . ILE B 2 90  ? 141.475 133.504 155.613 1.00 74.25  ?  93  ILE B CB  1 
ATOM   3132 C CG1 . ILE B 2 90  ? 140.647 134.564 156.336 1.00 70.63  ?  93  ILE B CG1 1 
ATOM   3133 C CG2 . ILE B 2 90  ? 142.696 133.134 156.419 1.00 66.85  ?  93  ILE B CG2 1 
ATOM   3134 C CD1 . ILE B 2 90  ? 139.670 134.001 157.323 1.00 74.44  ?  93  ILE B CD1 1 
ATOM   3135 N N   . PRO B 2 91  ? 143.709 132.984 152.918 1.00 86.91  ?  94  PRO B N   1 
ATOM   3136 C CA  . PRO B 2 91  ? 144.332 131.859 152.211 1.00 87.11  ?  94  PRO B CA  1 
ATOM   3137 C C   . PRO B 2 91  ? 144.781 130.791 153.198 1.00 89.93  ?  94  PRO B C   1 
ATOM   3138 O O   . PRO B 2 91  ? 145.507 131.075 154.153 1.00 84.13  ?  94  PRO B O   1 
ATOM   3139 C CB  . PRO B 2 91  ? 145.526 132.504 151.501 1.00 83.12  ?  94  PRO B CB  1 
ATOM   3140 C CG  . PRO B 2 91  ? 145.860 133.680 152.338 1.00 84.42  ?  94  PRO B CG  1 
ATOM   3141 C CD  . PRO B 2 91  ? 144.582 134.168 152.956 1.00 86.52  ?  94  PRO B CD  1 
ATOM   3142 N N   . LEU B 2 92  ? 144.345 129.559 152.962 1.00 89.65  ?  95  LEU B N   1 
ATOM   3143 C CA  . LEU B 2 92  ? 144.646 128.452 153.855 1.00 83.91  ?  95  LEU B CA  1 
ATOM   3144 C C   . LEU B 2 92  ? 145.952 127.782 153.455 1.00 90.33  ?  95  LEU B C   1 
ATOM   3145 O O   . LEU B 2 92  ? 146.269 127.670 152.268 1.00 89.43  ?  95  LEU B O   1 
ATOM   3146 C CB  . LEU B 2 92  ? 143.511 127.430 153.842 1.00 78.74  ?  95  LEU B CB  1 
ATOM   3147 C CG  . LEU B 2 92  ? 142.124 127.972 154.172 1.00 80.55  ?  95  LEU B CG  1 
ATOM   3148 C CD1 . LEU B 2 92  ? 141.059 126.989 153.749 1.00 77.28  ?  95  LEU B CD1 1 
ATOM   3149 C CD2 . LEU B 2 92  ? 142.019 128.278 155.646 1.00 83.15  ?  95  LEU B CD2 1 
ATOM   3150 N N   . ARG B 2 93  ? 146.711 127.343 154.460 1.00 95.76  ?  96  ARG B N   1 
ATOM   3151 C CA  . ARG B 2 93  ? 147.959 126.636 154.195 1.00 91.68  ?  96  ARG B CA  1 
ATOM   3152 C C   . ARG B 2 93  ? 147.706 125.324 153.467 1.00 96.46  ?  96  ARG B C   1 
ATOM   3153 O O   . ARG B 2 93  ? 148.458 124.952 152.560 1.00 98.10  ?  96  ARG B O   1 
ATOM   3154 C CB  . ARG B 2 93  ? 148.707 126.385 155.501 1.00 96.16  ?  96  ARG B CB  1 
ATOM   3155 C CG  . ARG B 2 93  ? 149.896 127.296 155.715 1.00 101.56 ?  96  ARG B CG  1 
ATOM   3156 C CD  . ARG B 2 93  ? 150.208 127.451 157.190 1.00 103.15 ?  96  ARG B CD  1 
ATOM   3157 N NE  . ARG B 2 93  ? 150.617 128.811 157.518 1.00 107.13 ?  96  ARG B NE  1 
ATOM   3158 C CZ  . ARG B 2 93  ? 150.613 129.319 158.742 1.00 104.72 ?  96  ARG B CZ  1 
ATOM   3159 N NH1 . ARG B 2 93  ? 150.229 128.605 159.785 1.00 101.86 1  96  ARG B NH1 1 
ATOM   3160 N NH2 . ARG B 2 93  ? 151.007 130.576 158.923 1.00 98.76  ?  96  ARG B NH2 1 
ATOM   3161 N N   . SER B 2 94  ? 146.659 124.605 153.856 1.00 93.32  ?  97  SER B N   1 
ATOM   3162 C CA  . SER B 2 94  ? 146.277 123.353 153.222 1.00 89.86  ?  97  SER B CA  1 
ATOM   3163 C C   . SER B 2 94  ? 144.952 123.540 152.502 1.00 88.69  ?  97  SER B C   1 
ATOM   3164 O O   . SER B 2 94  ? 143.975 123.998 153.101 1.00 96.36  ?  97  SER B O   1 
ATOM   3165 C CB  . SER B 2 94  ? 146.165 122.229 154.252 1.00 92.95  ?  97  SER B CB  1 
ATOM   3166 O OG  . SER B 2 94  ? 145.250 121.239 153.824 1.00 97.71  ?  97  SER B OG  1 
ATOM   3167 N N   . SER B 2 95  ? 144.921 123.182 151.219 1.00 85.56  ?  98  SER B N   1 
ATOM   3168 C CA  . SER B 2 95  ? 143.719 123.370 150.418 1.00 88.65  ?  98  SER B CA  1 
ATOM   3169 C C   . SER B 2 95  ? 142.595 122.425 150.811 1.00 85.04  ?  98  SER B C   1 
ATOM   3170 O O   . SER B 2 95  ? 141.442 122.676 150.452 1.00 90.10  ?  98  SER B O   1 
ATOM   3171 C CB  . SER B 2 95  ? 144.046 123.184 148.938 1.00 94.21  ?  98  SER B CB  1 
ATOM   3172 O OG  . SER B 2 95  ? 142.870 122.946 148.188 1.00 101.66 ?  98  SER B OG  1 
ATOM   3173 N N   . TRP B 2 96  ? 142.899 121.351 151.532 1.00 85.51  ?  99  TRP B N   1 
ATOM   3174 C CA  . TRP B 2 96  ? 141.921 120.314 151.847 1.00 85.68  ?  99  TRP B CA  1 
ATOM   3175 C C   . TRP B 2 96  ? 141.297 120.627 153.196 1.00 90.97  ?  99  TRP B C   1 
ATOM   3176 O O   . TRP B 2 96  ? 141.856 120.301 154.244 1.00 97.91  ?  99  TRP B O   1 
ATOM   3177 C CB  . TRP B 2 96  ? 142.586 118.944 151.834 1.00 90.62  ?  99  TRP B CB  1 
ATOM   3178 C CG  . TRP B 2 96  ? 143.515 118.789 150.687 1.00 86.70  ?  99  TRP B CG  1 
ATOM   3179 C CD1 . TRP B 2 96  ? 144.874 118.809 150.726 1.00 82.03  ?  99  TRP B CD1 1 
ATOM   3180 C CD2 . TRP B 2 96  ? 143.153 118.617 149.316 1.00 90.70  ?  99  TRP B CD2 1 
ATOM   3181 N NE1 . TRP B 2 96  ? 145.383 118.652 149.464 1.00 86.79  ?  99  TRP B NE1 1 
ATOM   3182 C CE2 . TRP B 2 96  ? 144.344 118.531 148.580 1.00 89.60  ?  99  TRP B CE2 1 
ATOM   3183 C CE3 . TRP B 2 96  ? 141.935 118.522 148.641 1.00 89.33  ?  99  TRP B CE3 1 
ATOM   3184 C CZ2 . TRP B 2 96  ? 144.355 118.354 147.204 1.00 93.17  ?  99  TRP B CZ2 1 
ATOM   3185 C CZ3 . TRP B 2 96  ? 141.947 118.348 147.277 1.00 86.42  ?  99  TRP B CZ3 1 
ATOM   3186 C CH2 . TRP B 2 96  ? 143.148 118.266 146.571 1.00 90.62  ?  99  TRP B CH2 1 
ATOM   3187 N N   . VAL B 2 97  ? 140.131 121.266 153.172 1.00 89.62  ?  100 VAL B N   1 
ATOM   3188 C CA  . VAL B 2 97  ? 139.424 121.664 154.380 1.00 89.36  ?  100 VAL B CA  1 
ATOM   3189 C C   . VAL B 2 97  ? 138.008 121.119 154.309 1.00 91.80  ?  100 VAL B C   1 
ATOM   3190 O O   . VAL B 2 97  ? 137.326 121.280 153.292 1.00 100.85 ?  100 VAL B O   1 
ATOM   3191 C CB  . VAL B 2 97  ? 139.412 123.193 154.562 1.00 84.93  ?  100 VAL B CB  1 
ATOM   3192 C CG1 . VAL B 2 97  ? 140.765 123.661 155.057 1.00 88.66  ?  100 VAL B CG1 1 
ATOM   3193 C CG2 . VAL B 2 97  ? 139.054 123.879 153.262 1.00 78.49  ?  100 VAL B CG2 1 
ATOM   3194 N N   . MET B 2 98  ? 137.572 120.467 155.381 1.00 87.23  ?  101 MET B N   1 
ATOM   3195 C CA  . MET B 2 98  ? 136.247 119.877 155.435 1.00 83.33  ?  101 MET B CA  1 
ATOM   3196 C C   . MET B 2 98  ? 135.363 120.493 156.505 1.00 83.35  ?  101 MET B C   1 
ATOM   3197 O O   . MET B 2 98  ? 134.182 120.143 156.584 1.00 90.50  ?  101 MET B O   1 
ATOM   3198 C CB  . MET B 2 98  ? 136.349 118.364 155.666 1.00 91.12  ?  101 MET B CB  1 
ATOM   3199 C CG  . MET B 2 98  ? 137.660 117.758 155.208 1.00 91.24  ?  101 MET B CG  1 
ATOM   3200 S SD  . MET B 2 98  ? 137.680 115.968 155.338 1.00 108.71 ?  101 MET B SD  1 
ATOM   3201 C CE  . MET B 2 98  ? 136.214 115.553 154.404 1.00 94.04  ?  101 MET B CE  1 
ATOM   3202 N N   . THR B 2 99  ? 135.891 121.397 157.324 1.00 83.74  ?  102 THR B N   1 
ATOM   3203 C CA  . THR B 2 99  ? 135.120 121.994 158.401 1.00 81.94  ?  102 THR B CA  1 
ATOM   3204 C C   . THR B 2 99  ? 135.470 123.467 158.530 1.00 80.48  ?  102 THR B C   1 
ATOM   3205 O O   . THR B 2 99  ? 136.528 123.919 158.089 1.00 75.33  ?  102 THR B O   1 
ATOM   3206 C CB  . THR B 2 99  ? 135.364 121.289 159.735 1.00 83.04  ?  102 THR B CB  1 
ATOM   3207 O OG1 . THR B 2 99  ? 134.697 122.011 160.775 1.00 93.58  ?  102 THR B OG1 1 
ATOM   3208 C CG2 . THR B 2 99  ? 136.844 121.234 160.043 1.00 79.34  ?  102 THR B CG2 1 
ATOM   3209 N N   . CYS B 2 100 ? 134.560 124.210 159.152 1.00 89.03  ?  103 CYS B N   1 
ATOM   3210 C CA  . CYS B 2 100 ? 134.708 125.646 159.316 1.00 76.50  ?  103 CYS B CA  1 
ATOM   3211 C C   . CYS B 2 100 ? 133.854 126.088 160.492 1.00 79.71  ?  103 CYS B C   1 
ATOM   3212 O O   . CYS B 2 100 ? 132.726 125.620 160.649 1.00 87.25  ?  103 CYS B O   1 
ATOM   3213 C CB  . CYS B 2 100 ? 134.292 126.386 158.044 1.00 61.00  ?  103 CYS B CB  1 
ATOM   3214 S SG  . CYS B 2 100 ? 134.694 128.112 158.049 1.00 97.66  ?  103 CYS B SG  1 
ATOM   3215 N N   . ALA B 2 101 ? 134.393 126.984 161.314 1.00 58.29  ?  104 ALA B N   1 
ATOM   3216 C CA  . ALA B 2 101 ? 133.685 127.455 162.492 1.00 46.97  ?  104 ALA B CA  1 
ATOM   3217 C C   . ALA B 2 101 ? 133.845 128.959 162.629 1.00 62.01  ?  104 ALA B C   1 
ATOM   3218 O O   . ALA B 2 101 ? 134.835 129.537 162.181 1.00 77.36  ?  104 ALA B O   1 
ATOM   3219 C CB  . ALA B 2 101 ? 134.184 126.767 163.764 1.00 52.79  ?  104 ALA B CB  1 
ATOM   3220 N N   . TYR B 2 102 ? 132.855 129.582 163.256 1.00 70.07  ?  105 TYR B N   1 
ATOM   3221 C CA  . TYR B 2 102 ? 132.861 131.002 163.569 1.00 55.73  ?  105 TYR B CA  1 
ATOM   3222 C C   . TYR B 2 102 ? 132.727 131.154 165.075 1.00 67.91  ?  105 TYR B C   1 
ATOM   3223 O O   . TYR B 2 102 ? 131.799 130.604 165.672 1.00 84.51  ?  105 TYR B O   1 
ATOM   3224 C CB  . TYR B 2 102 ? 131.715 131.721 162.857 1.00 56.99  ?  105 TYR B CB  1 
ATOM   3225 C CG  . TYR B 2 102 ? 132.033 133.122 162.398 1.00 67.88  ?  105 TYR B CG  1 
ATOM   3226 C CD1 . TYR B 2 102 ? 132.800 133.971 163.175 1.00 67.37  ?  105 TYR B CD1 1 
ATOM   3227 C CD2 . TYR B 2 102 ? 131.557 133.596 161.189 1.00 66.12  ?  105 TYR B CD2 1 
ATOM   3228 C CE1 . TYR B 2 102 ? 133.086 135.247 162.759 1.00 64.21  ?  105 TYR B CE1 1 
ATOM   3229 C CE2 . TYR B 2 102 ? 131.840 134.870 160.767 1.00 63.12  ?  105 TYR B CE2 1 
ATOM   3230 C CZ  . TYR B 2 102 ? 132.603 135.690 161.554 1.00 63.69  ?  105 TYR B CZ  1 
ATOM   3231 O OH  . TYR B 2 102 ? 132.885 136.964 161.132 1.00 76.08  ?  105 TYR B OH  1 
ATOM   3232 N N   . ALA B 2 103 ? 133.646 131.891 165.683 1.00 55.17  ?  106 ALA B N   1 
ATOM   3233 C CA  . ALA B 2 103 ? 133.599 132.070 167.124 1.00 54.06  ?  106 ALA B CA  1 
ATOM   3234 C C   . ALA B 2 103 ? 132.349 132.853 167.512 1.00 71.19  ?  106 ALA B C   1 
ATOM   3235 O O   . ALA B 2 103 ? 131.937 133.762 166.788 1.00 87.34  ?  106 ALA B O   1 
ATOM   3236 C CB  . ALA B 2 103 ? 134.844 132.798 167.618 1.00 54.11  ?  106 ALA B CB  1 
ATOM   3237 N N   . PRO B 2 104 ? 131.715 132.517 168.637 1.00 76.27  ?  107 PRO B N   1 
ATOM   3238 C CA  . PRO B 2 104 ? 130.540 133.290 169.067 1.00 71.83  ?  107 PRO B CA  1 
ATOM   3239 C C   . PRO B 2 104 ? 130.843 134.757 169.297 1.00 83.21  ?  107 PRO B C   1 
ATOM   3240 O O   . PRO B 2 104 ? 129.973 135.605 169.072 1.00 87.07  ?  107 PRO B O   1 
ATOM   3241 C CB  . PRO B 2 104 ? 130.116 132.587 170.363 1.00 76.28  ?  107 PRO B CB  1 
ATOM   3242 C CG  . PRO B 2 104 ? 130.719 131.233 170.279 1.00 79.96  ?  107 PRO B CG  1 
ATOM   3243 C CD  . PRO B 2 104 ? 132.007 131.406 169.553 1.00 79.00  ?  107 PRO B CD  1 
ATOM   3244 N N   . SER B 2 105 ? 132.057 135.082 169.742 1.00 93.48  ?  108 SER B N   1 
ATOM   3245 C CA  . SER B 2 105 ? 132.449 136.475 169.902 1.00 82.22  ?  108 SER B CA  1 
ATOM   3246 C C   . SER B 2 105 ? 132.727 137.152 168.570 1.00 81.18  ?  108 SER B C   1 
ATOM   3247 O O   . SER B 2 105 ? 132.745 138.385 168.509 1.00 95.12  ?  108 SER B O   1 
ATOM   3248 C CB  . SER B 2 105 ? 133.684 136.571 170.791 1.00 81.73  ?  108 SER B CB  1 
ATOM   3249 O OG  . SER B 2 105 ? 134.807 135.997 170.151 1.00 82.23  ?  108 SER B OG  1 
ATOM   3250 N N   . GLY B 2 106 ? 132.942 136.382 167.508 1.00 74.20  ?  109 GLY B N   1 
ATOM   3251 C CA  . GLY B 2 106 ? 133.233 136.934 166.207 1.00 73.35  ?  109 GLY B CA  1 
ATOM   3252 C C   . GLY B 2 106 ? 134.677 137.302 165.973 1.00 72.57  ?  109 GLY B C   1 
ATOM   3253 O O   . GLY B 2 106 ? 135.003 137.783 164.883 1.00 76.47  ?  109 GLY B O   1 
ATOM   3254 N N   . ASN B 2 107 ? 135.554 137.095 166.953 1.00 71.68  ?  110 ASN B N   1 
ATOM   3255 C CA  . ASN B 2 107 ? 136.952 137.470 166.798 1.00 70.92  ?  110 ASN B CA  1 
ATOM   3256 C C   . ASN B 2 107 ? 137.775 136.418 166.075 1.00 79.31  ?  110 ASN B C   1 
ATOM   3257 O O   . ASN B 2 107 ? 138.888 136.724 165.638 1.00 86.76  ?  110 ASN B O   1 
ATOM   3258 C CB  . ASN B 2 107 ? 137.586 137.742 168.163 1.00 74.88  ?  110 ASN B CB  1 
ATOM   3259 C CG  . ASN B 2 107 ? 136.819 138.761 168.970 1.00 83.72  ?  110 ASN B CG  1 
ATOM   3260 O OD1 . ASN B 2 107 ? 136.230 139.689 168.422 1.00 90.75  ?  110 ASN B OD1 1 
ATOM   3261 N ND2 . ASN B 2 107 ? 136.823 138.595 170.284 1.00 75.16  ?  110 ASN B ND2 1 
ATOM   3262 N N   . TYR B 2 108 ? 137.266 135.196 165.936 1.00 75.03  ?  111 TYR B N   1 
ATOM   3263 C CA  . TYR B 2 108 ? 138.056 134.102 165.395 1.00 63.65  ?  111 TYR B CA  1 
ATOM   3264 C C   . TYR B 2 108 ? 137.218 133.263 164.446 1.00 69.61  ?  111 TYR B C   1 
ATOM   3265 O O   . TYR B 2 108 ? 135.989 133.249 164.509 1.00 78.75  ?  111 TYR B O   1 
ATOM   3266 C CB  . TYR B 2 108 ? 138.613 133.202 166.504 1.00 66.52  ?  111 TYR B CB  1 
ATOM   3267 C CG  . TYR B 2 108 ? 139.505 133.910 167.488 1.00 66.72  ?  111 TYR B CG  1 
ATOM   3268 C CD1 . TYR B 2 108 ? 140.860 134.042 167.249 1.00 75.11  ?  111 TYR B CD1 1 
ATOM   3269 C CD2 . TYR B 2 108 ? 138.994 134.443 168.657 1.00 69.77  ?  111 TYR B CD2 1 
ATOM   3270 C CE1 . TYR B 2 108 ? 141.680 134.687 168.145 1.00 77.76  ?  111 TYR B CE1 1 
ATOM   3271 C CE2 . TYR B 2 108 ? 139.805 135.090 169.557 1.00 79.16  ?  111 TYR B CE2 1 
ATOM   3272 C CZ  . TYR B 2 108 ? 141.147 135.210 169.296 1.00 84.71  ?  111 TYR B CZ  1 
ATOM   3273 O OH  . TYR B 2 108 ? 141.964 135.855 170.193 1.00 84.73  ?  111 TYR B OH  1 
ATOM   3274 N N   . VAL B 2 109 ? 137.915 132.565 163.550 1.00 63.50  ?  112 VAL B N   1 
ATOM   3275 C CA  . VAL B 2 109 ? 137.350 131.485 162.757 1.00 57.66  ?  112 VAL B CA  1 
ATOM   3276 C C   . VAL B 2 109 ? 138.313 130.311 162.838 1.00 63.20  ?  112 VAL B C   1 
ATOM   3277 O O   . VAL B 2 109 ? 139.506 130.473 163.094 1.00 76.80  ?  112 VAL B O   1 
ATOM   3278 C CB  . VAL B 2 109 ? 137.099 131.879 161.285 1.00 56.40  ?  112 VAL B CB  1 
ATOM   3279 C CG1 . VAL B 2 109 ? 135.916 132.811 161.179 1.00 58.71  ?  112 VAL B CG1 1 
ATOM   3280 C CG2 . VAL B 2 109 ? 138.332 132.512 160.687 1.00 70.84  ?  112 VAL B CG2 1 
ATOM   3281 N N   . ALA B 2 110 ? 137.778 129.115 162.626 1.00 68.64  ?  113 ALA B N   1 
ATOM   3282 C CA  . ALA B 2 110 ? 138.569 127.897 162.673 1.00 63.97  ?  113 ALA B CA  1 
ATOM   3283 C C   . ALA B 2 110 ? 138.393 127.128 161.376 1.00 71.04  ?  113 ALA B C   1 
ATOM   3284 O O   . ALA B 2 110 ? 137.353 127.213 160.721 1.00 81.68  ?  113 ALA B O   1 
ATOM   3285 C CB  . ALA B 2 110 ? 138.180 127.013 163.855 1.00 62.84  ?  113 ALA B CB  1 
ATOM   3286 N N   . CYS B 2 111 ? 139.427 126.379 161.009 1.00 84.67  ?  114 CYS B N   1 
ATOM   3287 C CA  . CYS B 2 111 ? 139.403 125.589 159.790 1.00 77.28  ?  114 CYS B CA  1 
ATOM   3288 C C   . CYS B 2 111 ? 140.203 124.318 160.018 1.00 85.58  ?  114 CYS B C   1 
ATOM   3289 O O   . CYS B 2 111 ? 141.067 124.254 160.893 1.00 89.92  ?  114 CYS B O   1 
ATOM   3290 C CB  . CYS B 2 111 ? 139.966 126.376 158.604 1.00 80.68  ?  114 CYS B CB  1 
ATOM   3291 S SG  . CYS B 2 111 ? 139.085 126.118 157.061 1.00 108.18 ?  114 CYS B SG  1 
ATOM   3292 N N   . GLY B 2 112 ? 139.903 123.305 159.218 1.00 88.26  ?  115 GLY B N   1 
ATOM   3293 C CA  . GLY B 2 112 ? 140.616 122.046 159.308 1.00 79.77  ?  115 GLY B CA  1 
ATOM   3294 C C   . GLY B 2 112 ? 140.134 121.109 158.227 1.00 81.74  ?  115 GLY B C   1 
ATOM   3295 O O   . GLY B 2 112 ? 139.133 121.363 157.552 1.00 90.20  ?  115 GLY B O   1 
ATOM   3296 N N   . GLY B 2 113 ? 140.857 120.006 158.081 1.00 82.51  ?  116 GLY B N   1 
ATOM   3297 C CA  . GLY B 2 113 ? 140.531 119.045 157.049 1.00 81.93  ?  116 GLY B CA  1 
ATOM   3298 C C   . GLY B 2 113 ? 141.492 117.881 156.977 1.00 85.57  ?  116 GLY B C   1 
ATOM   3299 O O   . GLY B 2 113 ? 141.829 117.281 157.999 1.00 91.47  ?  116 GLY B O   1 
ATOM   3300 N N   . LEU B 2 114 ? 141.949 117.558 155.768 1.00 83.63  ?  117 LEU B N   1 
ATOM   3301 C CA  . LEU B 2 114 ? 142.810 116.400 155.563 1.00 83.03  ?  117 LEU B CA  1 
ATOM   3302 C C   . LEU B 2 114 ? 144.195 116.576 156.163 1.00 82.97  ?  117 LEU B C   1 
ATOM   3303 O O   . LEU B 2 114 ? 144.962 115.611 156.187 1.00 96.39  ?  117 LEU B O   1 
ATOM   3304 C CB  . LEU B 2 114 ? 142.929 116.092 154.073 1.00 87.33  ?  117 LEU B CB  1 
ATOM   3305 C CG  . LEU B 2 114 ? 141.651 115.608 153.391 1.00 81.40  ?  117 LEU B CG  1 
ATOM   3306 C CD1 . LEU B 2 114 ? 141.930 115.220 151.958 1.00 85.80  ?  117 LEU B CD1 1 
ATOM   3307 C CD2 . LEU B 2 114 ? 141.061 114.443 154.148 1.00 83.44  ?  117 LEU B CD2 1 
ATOM   3308 N N   . ASP B 2 115 ? 144.538 117.771 156.633 1.00 86.69  ?  118 ASP B N   1 
ATOM   3309 C CA  . ASP B 2 115 ? 145.828 118.009 157.265 1.00 80.73  ?  118 ASP B CA  1 
ATOM   3310 C C   . ASP B 2 115 ? 145.854 117.627 158.739 1.00 85.65  ?  118 ASP B C   1 
ATOM   3311 O O   . ASP B 2 115 ? 146.903 117.774 159.374 1.00 86.23  ?  118 ASP B O   1 
ATOM   3312 C CB  . ASP B 2 115 ? 146.225 119.478 157.104 1.00 89.97  ?  118 ASP B CB  1 
ATOM   3313 C CG  . ASP B 2 115 ? 145.097 120.430 157.453 1.00 101.10 ?  118 ASP B CG  1 
ATOM   3314 O OD1 . ASP B 2 115 ? 144.025 120.337 156.823 1.00 101.47 ?  118 ASP B OD1 1 
ATOM   3315 O OD2 . ASP B 2 115 ? 145.280 121.276 158.351 1.00 100.38 -1 118 ASP B OD2 1 
ATOM   3316 N N   . ASN B 2 116 ? 144.737 117.156 159.294 1.00 84.01  ?  119 ASN B N   1 
ATOM   3317 C CA  . ASN B 2 116 ? 144.636 116.718 160.687 1.00 84.09  ?  119 ASN B CA  1 
ATOM   3318 C C   . ASN B 2 116 ? 144.947 117.833 161.676 1.00 93.51  ?  119 ASN B C   1 
ATOM   3319 O O   . ASN B 2 116 ? 145.358 117.564 162.807 1.00 97.87  ?  119 ASN B O   1 
ATOM   3320 C CB  . ASN B 2 116 ? 145.546 115.517 160.965 1.00 81.95  ?  119 ASN B CB  1 
ATOM   3321 C CG  . ASN B 2 116 ? 145.365 114.406 159.964 1.00 85.32  ?  119 ASN B CG  1 
ATOM   3322 O OD1 . ASN B 2 116 ? 144.566 114.513 159.038 1.00 93.24  ?  119 ASN B OD1 1 
ATOM   3323 N ND2 . ASN B 2 116 ? 146.114 113.329 160.139 1.00 86.01  ?  119 ASN B ND2 1 
ATOM   3324 N N   . ILE B 2 117 ? 144.755 119.085 161.277 1.00 90.21  ?  120 ILE B N   1 
ATOM   3325 C CA  . ILE B 2 117 ? 145.101 120.239 162.095 1.00 84.64  ?  120 ILE B CA  1 
ATOM   3326 C C   . ILE B 2 117 ? 143.922 121.198 162.092 1.00 83.99  ?  120 ILE B C   1 
ATOM   3327 O O   . ILE B 2 117 ? 143.327 121.449 161.040 1.00 95.28  ?  120 ILE B O   1 
ATOM   3328 C CB  . ILE B 2 117 ? 146.372 120.938 161.577 1.00 82.59  ?  120 ILE B CB  1 
ATOM   3329 C CG1 . ILE B 2 117 ? 147.599 120.072 161.843 1.00 83.98  ?  120 ILE B CG1 1 
ATOM   3330 C CG2 . ILE B 2 117 ? 146.548 122.291 162.225 1.00 84.16  ?  120 ILE B CG2 1 
ATOM   3331 C CD1 . ILE B 2 117 ? 148.752 120.365 160.927 1.00 84.47  ?  120 ILE B CD1 1 
ATOM   3332 N N   . CYS B 2 118 ? 143.576 121.718 163.266 1.00 78.63  ?  121 CYS B N   1 
ATOM   3333 C CA  . CYS B 2 118 ? 142.586 122.779 163.392 1.00 80.12  ?  121 CYS B CA  1 
ATOM   3334 C C   . CYS B 2 118 ? 143.319 124.100 163.575 1.00 84.27  ?  121 CYS B C   1 
ATOM   3335 O O   . CYS B 2 118 ? 144.035 124.284 164.563 1.00 89.33  ?  121 CYS B O   1 
ATOM   3336 C CB  . CYS B 2 118 ? 141.644 122.519 164.565 1.00 79.53  ?  121 CYS B CB  1 
ATOM   3337 S SG  . CYS B 2 118 ? 140.266 123.670 164.672 1.00 92.76  ?  121 CYS B SG  1 
ATOM   3338 N N   . SER B 2 119 ? 143.140 125.013 162.627 1.00 89.26  ?  122 SER B N   1 
ATOM   3339 C CA  . SER B 2 119 ? 143.843 126.287 162.625 1.00 83.01  ?  122 SER B CA  1 
ATOM   3340 C C   . SER B 2 119 ? 142.897 127.398 163.052 1.00 87.97  ?  122 SER B C   1 
ATOM   3341 O O   . SER B 2 119 ? 141.798 127.527 162.508 1.00 94.12  ?  122 SER B O   1 
ATOM   3342 C CB  . SER B 2 119 ? 144.419 126.586 161.243 1.00 85.12  ?  122 SER B CB  1 
ATOM   3343 O OG  . SER B 2 119 ? 144.848 125.399 160.606 1.00 89.17  ?  122 SER B OG  1 
ATOM   3344 N N   . ILE B 2 120 ? 143.331 128.197 164.021 1.00 85.04  ?  123 ILE B N   1 
ATOM   3345 C CA  . ILE B 2 120 ? 142.548 129.308 164.546 1.00 82.01  ?  123 ILE B CA  1 
ATOM   3346 C C   . ILE B 2 120 ? 143.062 130.595 163.922 1.00 80.16  ?  123 ILE B C   1 
ATOM   3347 O O   . ILE B 2 120 ? 144.265 130.875 163.965 1.00 91.90  ?  123 ILE B O   1 
ATOM   3348 C CB  . ILE B 2 120 ? 142.630 129.368 166.079 1.00 78.62  ?  123 ILE B CB  1 
ATOM   3349 C CG1 . ILE B 2 120 ? 142.453 127.972 166.672 1.00 82.16  ?  123 ILE B CG1 1 
ATOM   3350 C CG2 . ILE B 2 120 ? 141.595 130.319 166.630 1.00 78.20  ?  123 ILE B CG2 1 
ATOM   3351 C CD1 . ILE B 2 120 ? 141.076 127.404 166.481 1.00 75.14  ?  123 ILE B CD1 1 
ATOM   3352 N N   . TYR B 2 121 ? 142.159 131.377 163.341 1.00 73.94  ?  124 TYR B N   1 
ATOM   3353 C CA  . TYR B 2 121 ? 142.515 132.615 162.664 1.00 70.76  ?  124 TYR B CA  1 
ATOM   3354 C C   . TYR B 2 121 ? 141.979 133.800 163.449 1.00 80.48  ?  124 TYR B C   1 
ATOM   3355 O O   . TYR B 2 121 ? 140.802 133.825 163.815 1.00 84.52  ?  124 TYR B O   1 
ATOM   3356 C CB  . TYR B 2 121 ? 141.964 132.639 161.240 1.00 69.63  ?  124 TYR B CB  1 
ATOM   3357 C CG  . TYR B 2 121 ? 142.624 131.641 160.326 1.00 80.01  ?  124 TYR B CG  1 
ATOM   3358 C CD1 . TYR B 2 121 ? 143.771 131.969 159.626 1.00 80.23  ?  124 TYR B CD1 1 
ATOM   3359 C CD2 . TYR B 2 121 ? 142.117 130.361 160.188 1.00 80.12  ?  124 TYR B CD2 1 
ATOM   3360 C CE1 . TYR B 2 121 ? 144.383 131.057 158.801 1.00 88.20  ?  124 TYR B CE1 1 
ATOM   3361 C CE2 . TYR B 2 121 ? 142.720 129.443 159.360 1.00 79.60  ?  124 TYR B CE2 1 
ATOM   3362 C CZ  . TYR B 2 121 ? 143.853 129.797 158.671 1.00 87.43  ?  124 TYR B CZ  1 
ATOM   3363 O OH  . TYR B 2 121 ? 144.463 128.885 157.845 1.00 88.81  ?  124 TYR B OH  1 
ATOM   3364 N N   . ASN B 2 122 ? 142.841 134.780 163.699 1.00 82.73  ?  125 ASN B N   1 
ATOM   3365 C CA  . ASN B 2 122 ? 142.459 135.990 164.413 1.00 72.05  ?  125 ASN B CA  1 
ATOM   3366 C C   . ASN B 2 122 ? 141.925 137.010 163.416 1.00 81.46  ?  125 ASN B C   1 
ATOM   3367 O O   . ASN B 2 122 ? 142.639 137.416 162.495 1.00 90.64  ?  125 ASN B O   1 
ATOM   3368 C CB  . ASN B 2 122 ? 143.648 136.560 165.179 1.00 76.67  ?  125 ASN B CB  1 
ATOM   3369 C CG  . ASN B 2 122 ? 143.234 137.540 166.246 1.00 85.07  ?  125 ASN B CG  1 
ATOM   3370 O OD1 . ASN B 2 122 ? 142.057 137.861 166.387 1.00 85.45  ?  125 ASN B OD1 1 
ATOM   3371 N ND2 . ASN B 2 122 ? 144.202 138.025 167.008 1.00 86.59  ?  125 ASN B ND2 1 
ATOM   3372 N N   . LEU B 2 123 ? 140.676 137.427 163.606 1.00 72.93  ?  126 LEU B N   1 
ATOM   3373 C CA  . LEU B 2 123 ? 140.032 138.350 162.681 1.00 62.18  ?  126 LEU B CA  1 
ATOM   3374 C C   . LEU B 2 123 ? 140.282 139.810 163.021 1.00 70.67  ?  126 LEU B C   1 
ATOM   3375 O O   . LEU B 2 123 ? 140.362 140.641 162.112 1.00 75.95  ?  126 LEU B O   1 
ATOM   3376 C CB  . LEU B 2 123 ? 138.526 138.097 162.654 1.00 61.05  ?  126 LEU B CB  1 
ATOM   3377 C CG  . LEU B 2 123 ? 138.068 136.786 162.030 1.00 52.34  ?  126 LEU B CG  1 
ATOM   3378 C CD1 . LEU B 2 123 ? 136.567 136.787 161.900 1.00 59.89  ?  126 LEU B CD1 1 
ATOM   3379 C CD2 . LEU B 2 123 ? 138.726 136.581 160.689 1.00 53.23  ?  126 LEU B CD2 1 
ATOM   3380 N N   . LYS B 2 124 ? 140.399 140.144 164.300 1.00 78.57  ?  127 LYS B N   1 
ATOM   3381 C CA  . LYS B 2 124 ? 140.563 141.524 164.745 1.00 78.06  ?  127 LYS B CA  1 
ATOM   3382 C C   . LYS B 2 124 ? 142.004 141.715 165.206 1.00 78.81  ?  127 LYS B C   1 
ATOM   3383 O O   . LYS B 2 124 ? 142.317 141.585 166.389 1.00 86.77  ?  127 LYS B O   1 
ATOM   3384 C CB  . LYS B 2 124 ? 139.577 141.857 165.853 1.00 81.88  ?  127 LYS B CB  1 
ATOM   3385 C CG  . LYS B 2 124 ? 138.292 141.067 165.788 1.00 79.16  ?  127 LYS B CG  1 
ATOM   3386 C CD  . LYS B 2 124 ? 137.170 141.891 165.200 1.00 74.11  ?  127 LYS B CD  1 
ATOM   3387 C CE  . LYS B 2 124 ? 135.883 141.102 165.163 1.00 83.48  ?  127 LYS B CE  1 
ATOM   3388 N NZ  . LYS B 2 124 ? 134.828 141.729 166.000 1.00 83.22  1  127 LYS B NZ  1 
ATOM   3389 N N   . THR B 2 125 ? 142.878 142.039 164.262 1.00 92.51  ?  128 THR B N   1 
ATOM   3390 C CA  . THR B 2 125 ? 144.271 142.339 164.542 1.00 96.88  ?  128 THR B CA  1 
ATOM   3391 C C   . THR B 2 125 ? 144.541 143.810 164.263 1.00 99.89  ?  128 THR B C   1 
ATOM   3392 O O   . THR B 2 125 ? 143.932 144.412 163.376 1.00 103.35 ?  128 THR B O   1 
ATOM   3393 C CB  . THR B 2 125 ? 145.210 141.474 163.697 1.00 98.17  ?  128 THR B CB  1 
ATOM   3394 O OG1 . THR B 2 125 ? 144.604 141.209 162.428 1.00 102.10 ?  128 THR B OG1 1 
ATOM   3395 C CG2 . THR B 2 125 ? 145.495 140.161 164.393 1.00 95.96  ?  128 THR B CG2 1 
ATOM   3396 N N   . ARG B 2 126 ? 145.457 144.391 165.038 1.00 106.49 ?  129 ARG B N   1 
ATOM   3397 C CA  . ARG B 2 126 ? 145.848 145.775 164.806 1.00 104.19 ?  129 ARG B CA  1 
ATOM   3398 C C   . ARG B 2 126 ? 146.572 145.954 163.481 1.00 106.24 ?  129 ARG B C   1 
ATOM   3399 O O   . ARG B 2 126 ? 146.660 147.080 162.984 1.00 110.55 ?  129 ARG B O   1 
ATOM   3400 C CB  . ARG B 2 126 ? 146.727 146.273 165.951 1.00 107.64 ?  129 ARG B CB  1 
ATOM   3401 C CG  . ARG B 2 126 ? 145.966 146.531 167.236 1.00 110.01 ?  129 ARG B CG  1 
ATOM   3402 C CD  . ARG B 2 126 ? 145.839 148.017 167.509 1.00 110.68 ?  129 ARG B CD  1 
ATOM   3403 N NE  . ARG B 2 126 ? 147.141 148.665 167.596 1.00 117.38 ?  129 ARG B NE  1 
ATOM   3404 C CZ  . ARG B 2 126 ? 147.339 149.969 167.463 1.00 119.23 ?  129 ARG B CZ  1 
ATOM   3405 N NH1 . ARG B 2 126 ? 146.336 150.800 167.233 1.00 110.57 1  129 ARG B NH1 1 
ATOM   3406 N NH2 . ARG B 2 126 ? 148.574 150.451 167.564 1.00 116.18 ?  129 ARG B NH2 1 
ATOM   3407 N N   . GLU B 2 127 ? 147.090 144.874 162.901 1.00 100.82 ?  130 GLU B N   1 
ATOM   3408 C CA  . GLU B 2 127 ? 147.767 144.935 161.615 1.00 97.43  ?  130 GLU B CA  1 
ATOM   3409 C C   . GLU B 2 127 ? 146.803 145.018 160.442 1.00 96.14  ?  130 GLU B C   1 
ATOM   3410 O O   . GLU B 2 127 ? 147.239 145.304 159.324 1.00 102.37 ?  130 GLU B O   1 
ATOM   3411 C CB  . GLU B 2 127 ? 148.667 143.712 161.443 1.00 98.75  ?  130 GLU B CB  1 
ATOM   3412 C CG  . GLU B 2 127 ? 150.041 143.866 162.049 1.00 103.46 ?  130 GLU B CG  1 
ATOM   3413 C CD  . GLU B 2 127 ? 150.046 143.577 163.533 1.00 109.59 ?  130 GLU B CD  1 
ATOM   3414 O OE1 . GLU B 2 127 ? 149.240 142.732 163.974 1.00 108.10 ?  130 GLU B OE1 1 
ATOM   3415 O OE2 . GLU B 2 127 ? 150.855 144.191 164.260 1.00 109.91 -1 130 GLU B OE2 1 
ATOM   3416 N N   . GLY B 2 128 ? 145.518 144.765 160.660 1.00 85.74  ?  131 GLY B N   1 
ATOM   3417 C CA  . GLY B 2 128 ? 144.534 144.851 159.606 1.00 90.06  ?  131 GLY B CA  1 
ATOM   3418 C C   . GLY B 2 128 ? 144.423 143.634 158.721 1.00 95.72  ?  131 GLY B C   1 
ATOM   3419 O O   . GLY B 2 128 ? 143.613 143.643 157.786 1.00 96.76  ?  131 GLY B O   1 
ATOM   3420 N N   . ASN B 2 129 ? 145.201 142.589 158.977 1.00 100.84 ?  132 ASN B N   1 
ATOM   3421 C CA  . ASN B 2 129 ? 145.145 141.361 158.204 1.00 91.46  ?  132 ASN B CA  1 
ATOM   3422 C C   . ASN B 2 129 ? 144.799 140.197 159.120 1.00 93.64  ?  132 ASN B C   1 
ATOM   3423 O O   . ASN B 2 129 ? 145.027 140.243 160.331 1.00 108.20 ?  132 ASN B O   1 
ATOM   3424 C CB  . ASN B 2 129 ? 146.471 141.093 157.483 1.00 92.47  ?  132 ASN B CB  1 
ATOM   3425 C CG  . ASN B 2 129 ? 147.656 141.061 158.427 1.00 100.99 ?  132 ASN B CG  1 
ATOM   3426 O OD1 . ASN B 2 129 ? 147.519 141.298 159.624 1.00 101.95 ?  132 ASN B OD1 1 
ATOM   3427 N ND2 . ASN B 2 129 ? 148.831 140.774 157.887 1.00 98.69  ?  132 ASN B ND2 1 
ATOM   3428 N N   . VAL B 2 130 ? 144.233 139.152 158.530 1.00 80.07  ?  133 VAL B N   1 
ATOM   3429 C CA  . VAL B 2 130 ? 143.878 137.955 159.282 1.00 83.74  ?  133 VAL B CA  1 
ATOM   3430 C C   . VAL B 2 130 ? 145.119 137.086 159.423 1.00 83.90  ?  133 VAL B C   1 
ATOM   3431 O O   . VAL B 2 130 ? 145.720 136.676 158.425 1.00 86.11  ?  133 VAL B O   1 
ATOM   3432 C CB  . VAL B 2 130 ? 142.742 137.187 158.596 1.00 78.63  ?  133 VAL B CB  1 
ATOM   3433 C CG1 . VAL B 2 130 ? 142.468 135.897 159.332 1.00 81.18  ?  133 VAL B CG1 1 
ATOM   3434 C CG2 . VAL B 2 130 ? 141.498 138.039 158.539 1.00 77.90  ?  133 VAL B CG2 1 
ATOM   3435 N N   . ARG B 2 131 ? 145.506 136.806 160.661 1.00 95.63  ?  134 ARG B N   1 
ATOM   3436 C CA  . ARG B 2 131 ? 146.660 135.975 160.958 1.00 94.41  ?  134 ARG B CA  1 
ATOM   3437 C C   . ARG B 2 131 ? 146.210 134.691 161.637 1.00 98.14  ?  134 ARG B C   1 
ATOM   3438 O O   . ARG B 2 131 ? 145.196 134.664 162.338 1.00 107.38 ?  134 ARG B O   1 
ATOM   3439 C CB  . ARG B 2 131 ? 147.655 136.705 161.861 1.00 95.41  ?  134 ARG B CB  1 
ATOM   3440 C CG  . ARG B 2 131 ? 148.430 137.810 161.179 1.00 105.94 ?  134 ARG B CG  1 
ATOM   3441 C CD  . ARG B 2 131 ? 149.609 138.252 162.026 1.00 107.58 ?  134 ARG B CD  1 
ATOM   3442 N NE  . ARG B 2 131 ? 149.204 139.094 163.145 1.00 115.14 ?  134 ARG B NE  1 
ATOM   3443 C CZ  . ARG B 2 131 ? 149.022 138.658 164.384 1.00 112.04 ?  134 ARG B CZ  1 
ATOM   3444 N NH1 . ARG B 2 131 ? 149.177 137.383 164.698 1.00 104.15 1  134 ARG B NH1 1 
ATOM   3445 N NH2 . ARG B 2 131 ? 148.674 139.524 165.332 1.00 105.62 ?  134 ARG B NH2 1 
ATOM   3446 N N   . VAL B 2 132 ? 146.974 133.624 161.425 1.00 90.01  ?  135 VAL B N   1 
ATOM   3447 C CA  . VAL B 2 132 ? 146.694 132.373 162.117 1.00 92.81  ?  135 VAL B CA  1 
ATOM   3448 C C   . VAL B 2 132 ? 147.100 132.527 163.577 1.00 87.25  ?  135 VAL B C   1 
ATOM   3449 O O   . VAL B 2 132 ? 148.225 132.930 163.893 1.00 88.00  ?  135 VAL B O   1 
ATOM   3450 C CB  . VAL B 2 132 ? 147.396 131.191 161.430 1.00 88.63  ?  135 VAL B CB  1 
ATOM   3451 C CG1 . VAL B 2 132 ? 148.905 131.272 161.563 1.00 92.93  ?  135 VAL B CG1 1 
ATOM   3452 C CG2 . VAL B 2 132 ? 146.883 129.878 161.982 1.00 82.27  ?  135 VAL B CG2 1 
ATOM   3453 N N   . SER B 2 133 ? 146.160 132.259 164.480 1.00 87.93  ?  136 SER B N   1 
ATOM   3454 C CA  . SER B 2 133 ? 146.425 132.460 165.898 1.00 90.40  ?  136 SER B CA  1 
ATOM   3455 C C   . SER B 2 133 ? 147.119 131.252 166.508 1.00 91.21  ?  136 SER B C   1 
ATOM   3456 O O   . SER B 2 133 ? 148.036 131.406 167.321 1.00 89.86  ?  136 SER B O   1 
ATOM   3457 C CB  . SER B 2 133 ? 145.121 132.761 166.635 1.00 93.27  ?  136 SER B CB  1 
ATOM   3458 O OG  . SER B 2 133 ? 145.339 132.894 168.026 1.00 99.35  ?  136 SER B OG  1 
ATOM   3459 N N   . ARG B 2 134 ? 146.702 130.051 166.122 1.00 100.86 ?  137 ARG B N   1 
ATOM   3460 C CA  . ARG B 2 134 ? 147.300 128.827 166.628 1.00 97.08  ?  137 ARG B CA  1 
ATOM   3461 C C   . ARG B 2 134 ? 146.876 127.673 165.738 1.00 99.01  ?  137 ARG B C   1 
ATOM   3462 O O   . ARG B 2 134 ? 145.752 127.646 165.234 1.00 96.16  ?  137 ARG B O   1 
ATOM   3463 C CB  . ARG B 2 134 ? 146.888 128.558 168.079 1.00 91.00  ?  137 ARG B CB  1 
ATOM   3464 C CG  . ARG B 2 134 ? 147.430 127.259 168.631 1.00 100.01 ?  137 ARG B CG  1 
ATOM   3465 C CD  . ARG B 2 134 ? 147.642 127.335 170.122 1.00 104.58 ?  137 ARG B CD  1 
ATOM   3466 N NE  . ARG B 2 134 ? 147.862 128.702 170.575 1.00 106.51 ?  137 ARG B NE  1 
ATOM   3467 C CZ  . ARG B 2 134 ? 149.040 129.308 170.578 1.00 107.18 ?  137 ARG B CZ  1 
ATOM   3468 N NH1 . ARG B 2 134 ? 150.134 128.694 170.158 1.00 104.61 1  137 ARG B NH1 1 
ATOM   3469 N NH2 . ARG B 2 134 ? 149.124 130.562 171.014 1.00 102.36 ?  137 ARG B NH2 1 
ATOM   3470 N N   . GLU B 2 135 ? 147.792 126.729 165.543 1.00 99.93  ?  138 GLU B N   1 
ATOM   3471 C CA  . GLU B 2 135 ? 147.510 125.481 164.848 1.00 98.36  ?  138 GLU B CA  1 
ATOM   3472 C C   . GLU B 2 135 ? 147.410 124.371 165.883 1.00 99.37  ?  138 GLU B C   1 
ATOM   3473 O O   . GLU B 2 135 ? 148.393 124.067 166.566 1.00 100.56 ?  138 GLU B O   1 
ATOM   3474 C CB  . GLU B 2 135 ? 148.595 125.167 163.822 1.00 95.16  ?  138 GLU B CB  1 
ATOM   3475 C CG  . GLU B 2 135 ? 148.243 125.577 162.411 1.00 101.55 ?  138 GLU B CG  1 
ATOM   3476 C CD  . GLU B 2 135 ? 149.434 126.117 161.654 1.00 109.19 ?  138 GLU B CD  1 
ATOM   3477 O OE1 . GLU B 2 135 ? 150.529 126.193 162.248 1.00 109.70 ?  138 GLU B OE1 1 
ATOM   3478 O OE2 . GLU B 2 135 ? 149.278 126.466 160.466 1.00 107.66 -1 138 GLU B OE2 1 
ATOM   3479 N N   . LEU B 2 136 ? 146.229 123.774 166.000 1.00 86.92  ?  139 LEU B N   1 
ATOM   3480 C CA  . LEU B 2 136 ? 145.980 122.731 166.988 1.00 79.85  ?  139 LEU B CA  1 
ATOM   3481 C C   . LEU B 2 136 ? 146.274 121.380 166.351 1.00 88.08  ?  139 LEU B C   1 
ATOM   3482 O O   . LEU B 2 136 ? 145.557 120.941 165.447 1.00 95.75  ?  139 LEU B O   1 
ATOM   3483 C CB  . LEU B 2 136 ? 144.543 122.802 167.497 1.00 79.49  ?  139 LEU B CB  1 
ATOM   3484 C CG  . LEU B 2 136 ? 144.087 124.135 168.087 1.00 77.05  ?  139 LEU B CG  1 
ATOM   3485 C CD1 . LEU B 2 136 ? 142.587 124.145 168.262 1.00 79.67  ?  139 LEU B CD1 1 
ATOM   3486 C CD2 . LEU B 2 136 ? 144.773 124.400 169.407 1.00 83.22  ?  139 LEU B CD2 1 
ATOM   3487 N N   . ALA B 2 137 ? 147.323 120.719 166.826 1.00 90.42  ?  140 ALA B N   1 
ATOM   3488 C CA  . ALA B 2 137 ? 147.745 119.431 166.305 1.00 86.77  ?  140 ALA B CA  1 
ATOM   3489 C C   . ALA B 2 137 ? 147.628 118.374 167.392 1.00 93.87  ?  140 ALA B C   1 
ATOM   3490 O O   . ALA B 2 137 ? 147.742 118.670 168.584 1.00 96.24  ?  140 ALA B O   1 
ATOM   3491 C CB  . ALA B 2 137 ? 149.182 119.487 165.784 1.00 80.74  ?  140 ALA B CB  1 
ATOM   3492 N N   . GLY B 2 138 ? 147.403 117.135 166.969 1.00 88.84  ?  141 GLY B N   1 
ATOM   3493 C CA  . GLY B 2 138 ? 147.217 116.047 167.906 1.00 91.77  ?  141 GLY B CA  1 
ATOM   3494 C C   . GLY B 2 138 ? 146.218 115.014 167.432 1.00 95.32  ?  141 GLY B C   1 
ATOM   3495 O O   . GLY B 2 138 ? 146.188 113.892 167.942 1.00 96.86  ?  141 GLY B O   1 
ATOM   3496 N N   . HIS B 2 139 ? 145.396 115.379 166.457 1.00 90.84  ?  142 HIS B N   1 
ATOM   3497 C CA  . HIS B 2 139 ? 144.492 114.424 165.838 1.00 87.53  ?  142 HIS B CA  1 
ATOM   3498 C C   . HIS B 2 139 ? 145.251 113.595 164.813 1.00 93.87  ?  142 HIS B C   1 
ATOM   3499 O O   . HIS B 2 139 ? 146.035 114.127 164.023 1.00 100.05 ?  142 HIS B O   1 
ATOM   3500 C CB  . HIS B 2 139 ? 143.324 115.144 165.166 1.00 90.29  ?  142 HIS B CB  1 
ATOM   3501 C CG  . HIS B 2 139 ? 142.135 115.333 166.054 1.00 95.99  ?  142 HIS B CG  1 
ATOM   3502 N ND1 . HIS B 2 139 ? 141.706 114.369 166.938 1.00 94.07  ?  142 HIS B ND1 1 
ATOM   3503 C CD2 . HIS B 2 139 ? 141.280 116.372 166.188 1.00 94.07  ?  142 HIS B CD2 1 
ATOM   3504 C CE1 . HIS B 2 139 ? 140.639 114.807 167.581 1.00 90.49  ?  142 HIS B CE1 1 
ATOM   3505 N NE2 . HIS B 2 139 ? 140.360 116.021 167.145 1.00 91.16  ?  142 HIS B NE2 1 
ATOM   3506 N N   . THR B 2 140 ? 145.026 112.286 164.834 1.00 88.46  ?  143 THR B N   1 
ATOM   3507 C CA  . THR B 2 140 ? 145.680 111.383 163.899 1.00 86.34  ?  143 THR B CA  1 
ATOM   3508 C C   . THR B 2 140 ? 144.834 111.093 162.669 1.00 88.41  ?  143 THR B C   1 
ATOM   3509 O O   . THR B 2 140 ? 145.250 110.298 161.822 1.00 88.87  ?  143 THR B O   1 
ATOM   3510 C CB  . THR B 2 140 ? 146.045 110.071 164.595 1.00 86.12  ?  143 THR B CB  1 
ATOM   3511 O OG1 . THR B 2 140 ? 144.928 109.179 164.551 1.00 93.54  ?  143 THR B OG1 1 
ATOM   3512 C CG2 . THR B 2 140 ? 146.421 110.329 166.040 1.00 86.15  ?  143 THR B CG2 1 
ATOM   3513 N N   . GLY B 2 141 ? 143.658 111.713 162.553 1.00 81.66  ?  144 GLY B N   1 
ATOM   3514 C CA  . GLY B 2 141 ? 142.833 111.574 161.376 1.00 71.46  ?  144 GLY B CA  1 
ATOM   3515 C C   . GLY B 2 141 ? 142.336 112.933 160.920 1.00 78.34  ?  144 GLY B C   1 
ATOM   3516 O O   . GLY B 2 141 ? 142.541 113.945 161.589 1.00 87.16  ?  144 GLY B O   1 
ATOM   3517 N N   . TYR B 2 142 ? 141.674 112.936 159.767 1.00 86.46  ?  145 TYR B N   1 
ATOM   3518 C CA  . TYR B 2 142 ? 141.195 114.185 159.195 1.00 79.46  ?  145 TYR B CA  1 
ATOM   3519 C C   . TYR B 2 142 ? 140.171 114.840 160.112 1.00 83.35  ?  145 TYR B C   1 
ATOM   3520 O O   . TYR B 2 142 ? 139.393 114.169 160.791 1.00 92.71  ?  145 TYR B O   1 
ATOM   3521 C CB  . TYR B 2 142 ? 140.589 113.947 157.811 1.00 78.51  ?  145 TYR B CB  1 
ATOM   3522 C CG  . TYR B 2 142 ? 139.340 113.100 157.809 1.00 84.65  ?  145 TYR B CG  1 
ATOM   3523 C CD1 . TYR B 2 142 ? 139.415 111.722 157.705 1.00 89.92  ?  145 TYR B CD1 1 
ATOM   3524 C CD2 . TYR B 2 142 ? 138.086 113.679 157.900 1.00 82.81  ?  145 TYR B CD2 1 
ATOM   3525 C CE1 . TYR B 2 142 ? 138.279 110.948 157.700 1.00 90.30  ?  145 TYR B CE1 1 
ATOM   3526 C CE2 . TYR B 2 142 ? 136.947 112.912 157.898 1.00 82.79  ?  145 TYR B CE2 1 
ATOM   3527 C CZ  . TYR B 2 142 ? 137.049 111.547 157.798 1.00 89.08  ?  145 TYR B CZ  1 
ATOM   3528 O OH  . TYR B 2 142 ? 135.912 110.778 157.794 1.00 94.55  ?  145 TYR B OH  1 
ATOM   3529 N N   . LEU B 2 143 ? 140.184 116.168 160.131 1.00 84.33  ?  146 LEU B N   1 
ATOM   3530 C CA  . LEU B 2 143 ? 139.245 116.934 160.937 1.00 75.33  ?  146 LEU B CA  1 
ATOM   3531 C C   . LEU B 2 143 ? 137.926 117.067 160.190 1.00 81.54  ?  146 LEU B C   1 
ATOM   3532 O O   . LEU B 2 143 ? 137.893 117.568 159.063 1.00 90.97  ?  146 LEU B O   1 
ATOM   3533 C CB  . LEU B 2 143 ? 139.823 118.307 161.254 1.00 79.90  ?  146 LEU B CB  1 
ATOM   3534 C CG  . LEU B 2 143 ? 139.614 118.811 162.676 1.00 88.02  ?  146 LEU B CG  1 
ATOM   3535 C CD1 . LEU B 2 143 ? 140.822 118.479 163.519 1.00 83.64  ?  146 LEU B CD1 1 
ATOM   3536 C CD2 . LEU B 2 143 ? 139.355 120.300 162.666 1.00 91.56  ?  146 LEU B CD2 1 
ATOM   3537 N N   . SER B 2 144 ? 136.838 116.628 160.817 1.00 71.16  ?  147 SER B N   1 
ATOM   3538 C CA  . SER B 2 144 ? 135.531 116.632 160.176 1.00 70.80  ?  147 SER B CA  1 
ATOM   3539 C C   . SER B 2 144 ? 134.606 117.730 160.670 1.00 82.77  ?  147 SER B C   1 
ATOM   3540 O O   . SER B 2 144 ? 133.721 118.148 159.924 1.00 94.14  ?  147 SER B O   1 
ATOM   3541 C CB  . SER B 2 144 ? 134.842 115.278 160.370 1.00 67.41  ?  147 SER B CB  1 
ATOM   3542 O OG  . SER B 2 144 ? 134.925 114.860 161.717 1.00 80.99  ?  147 SER B OG  1 
ATOM   3543 N N   . CYS B 2 145 ? 134.781 118.203 161.900 1.00 79.27  ?  148 CYS B N   1 
ATOM   3544 C CA  . CYS B 2 145 ? 133.958 119.284 162.418 1.00 73.65  ?  148 CYS B CA  1 
ATOM   3545 C C   . CYS B 2 145 ? 134.714 119.982 163.535 1.00 80.27  ?  148 CYS B C   1 
ATOM   3546 O O   . CYS B 2 145 ? 135.618 119.414 164.148 1.00 84.74  ?  148 CYS B O   1 
ATOM   3547 C CB  . CYS B 2 145 ? 132.605 118.775 162.920 1.00 69.88  ?  148 CYS B CB  1 
ATOM   3548 S SG  . CYS B 2 145 ? 131.313 120.029 162.972 1.00 90.24  ?  148 CYS B SG  1 
ATOM   3549 N N   . CYS B 2 146 ? 134.333 121.231 163.782 1.00 81.12  ?  149 CYS B N   1 
ATOM   3550 C CA  . CYS B 2 146 ? 134.880 122.010 164.880 1.00 71.34  ?  149 CYS B CA  1 
ATOM   3551 C C   . CYS B 2 146 ? 133.857 123.062 165.265 1.00 80.41  ?  149 CYS B C   1 
ATOM   3552 O O   . CYS B 2 146 ? 133.228 123.670 164.397 1.00 89.38  ?  149 CYS B O   1 
ATOM   3553 C CB  . CYS B 2 146 ? 136.213 122.669 164.507 1.00 71.49  ?  149 CYS B CB  1 
ATOM   3554 S SG  . CYS B 2 146 ? 136.181 123.667 163.011 1.00 92.74  ?  149 CYS B SG  1 
ATOM   3555 N N   . ARG B 2 147 ? 133.679 123.259 166.567 1.00 65.95  ?  150 ARG B N   1 
ATOM   3556 C CA  . ARG B 2 147 ? 132.731 124.237 167.075 1.00 60.97  ?  150 ARG B CA  1 
ATOM   3557 C C   . ARG B 2 147 ? 133.359 124.966 168.248 1.00 71.82  ?  150 ARG B C   1 
ATOM   3558 O O   . ARG B 2 147 ? 133.860 124.331 169.177 1.00 81.06  ?  150 ARG B O   1 
ATOM   3559 C CB  . ARG B 2 147 ? 131.424 123.572 167.508 1.00 63.25  ?  150 ARG B CB  1 
ATOM   3560 C CG  . ARG B 2 147 ? 130.487 123.228 166.366 1.00 67.37  ?  150 ARG B CG  1 
ATOM   3561 C CD  . ARG B 2 147 ? 130.144 124.452 165.548 1.00 68.03  ?  150 ARG B CD  1 
ATOM   3562 N NE  . ARG B 2 147 ? 129.453 124.109 164.312 1.00 62.00  ?  150 ARG B NE  1 
ATOM   3563 C CZ  . ARG B 2 147 ? 130.008 124.155 163.110 1.00 75.65  ?  150 ARG B CZ  1 
ATOM   3564 N NH1 . ARG B 2 147 ? 131.272 124.504 162.948 1.00 84.25  1  150 ARG B NH1 1 
ATOM   3565 N NH2 . ARG B 2 147 ? 129.278 123.843 162.046 1.00 70.25  ?  150 ARG B NH2 1 
ATOM   3566 N N   . PHE B 2 148 ? 133.330 126.292 168.202 1.00 76.26  ?  151 PHE B N   1 
ATOM   3567 C CA  . PHE B 2 148 ? 133.864 127.087 169.296 1.00 61.82  ?  151 PHE B CA  1 
ATOM   3568 C C   . PHE B 2 148 ? 132.946 127.009 170.505 1.00 67.51  ?  151 PHE B C   1 
ATOM   3569 O O   . PHE B 2 148 ? 131.722 127.079 170.381 1.00 77.72  ?  151 PHE B O   1 
ATOM   3570 C CB  . PHE B 2 148 ? 134.013 128.543 168.871 1.00 68.32  ?  151 PHE B CB  1 
ATOM   3571 C CG  . PHE B 2 148 ? 135.305 128.858 168.190 1.00 62.36  ?  151 PHE B CG  1 
ATOM   3572 C CD1 . PHE B 2 148 ? 136.427 129.176 168.922 1.00 65.52  ?  151 PHE B CD1 1 
ATOM   3573 C CD2 . PHE B 2 148 ? 135.388 128.868 166.813 1.00 60.53  ?  151 PHE B CD2 1 
ATOM   3574 C CE1 . PHE B 2 148 ? 137.610 129.479 168.295 1.00 68.38  ?  151 PHE B CE1 1 
ATOM   3575 C CE2 . PHE B 2 148 ? 136.565 129.172 166.185 1.00 60.87  ?  151 PHE B CE2 1 
ATOM   3576 C CZ  . PHE B 2 148 ? 137.678 129.478 166.926 1.00 68.60  ?  151 PHE B CZ  1 
ATOM   3577 N N   . LEU B 2 149 ? 133.544 126.864 171.682 1.00 83.19  ?  152 LEU B N   1 
ATOM   3578 C CA  . LEU B 2 149 ? 132.809 127.044 172.926 1.00 83.44  ?  152 LEU B CA  1 
ATOM   3579 C C   . LEU B 2 149 ? 132.894 128.484 173.407 1.00 92.46  ?  152 LEU B C   1 
ATOM   3580 O O   . LEU B 2 149 ? 131.883 129.071 173.805 1.00 89.46  ?  152 LEU B O   1 
ATOM   3581 C CB  . LEU B 2 149 ? 133.348 126.098 173.999 1.00 73.51  ?  152 LEU B CB  1 
ATOM   3582 C CG  . LEU B 2 149 ? 132.824 124.667 173.958 1.00 77.30  ?  152 LEU B CG  1 
ATOM   3583 C CD1 . LEU B 2 149 ? 133.929 123.705 174.300 1.00 87.71  ?  152 LEU B CD1 1 
ATOM   3584 C CD2 . LEU B 2 149 ? 131.686 124.509 174.931 1.00 88.74  ?  152 LEU B CD2 1 
ATOM   3585 N N   . ASP B 2 150 ? 134.090 129.055 173.368 1.00 102.23 ?  153 ASP B N   1 
ATOM   3586 C CA  . ASP B 2 150 ? 134.322 130.468 173.614 1.00 95.33  ?  153 ASP B CA  1 
ATOM   3587 C C   . ASP B 2 150 ? 135.617 130.839 172.899 1.00 96.02  ?  153 ASP B C   1 
ATOM   3588 O O   . ASP B 2 150 ? 136.101 130.091 172.046 1.00 97.90  ?  153 ASP B O   1 
ATOM   3589 C CB  . ASP B 2 150 ? 134.345 130.765 175.123 1.00 94.86  ?  153 ASP B CB  1 
ATOM   3590 C CG  . ASP B 2 150 ? 135.393 129.966 175.859 1.00 106.50 ?  153 ASP B CG  1 
ATOM   3591 O OD1 . ASP B 2 150 ? 136.588 130.310 175.751 1.00 109.66 ?  153 ASP B OD1 1 
ATOM   3592 O OD2 . ASP B 2 150 ? 135.022 128.998 176.554 1.00 107.65 -1 153 ASP B OD2 1 
ATOM   3593 N N   . ASP B 2 151 ? 136.178 131.999 173.237 1.00 100.79 ?  154 ASP B N   1 
ATOM   3594 C CA  . ASP B 2 151 ? 137.384 132.457 172.558 1.00 97.68  ?  154 ASP B CA  1 
ATOM   3595 C C   . ASP B 2 151 ? 138.579 131.550 172.812 1.00 101.77 ?  154 ASP B C   1 
ATOM   3596 O O   . ASP B 2 151 ? 139.535 131.575 172.031 1.00 107.03 ?  154 ASP B O   1 
ATOM   3597 C CB  . ASP B 2 151 ? 137.720 133.881 172.993 1.00 101.05 ?  154 ASP B CB  1 
ATOM   3598 C CG  . ASP B 2 151 ? 137.320 134.912 171.964 1.00 107.58 ?  154 ASP B CG  1 
ATOM   3599 O OD1 . ASP B 2 151 ? 136.377 134.645 171.191 1.00 111.85 ?  154 ASP B OD1 1 
ATOM   3600 O OD2 . ASP B 2 151 ? 137.946 135.992 171.930 1.00 107.09 -1 154 ASP B OD2 1 
ATOM   3601 N N   . ASN B 2 152 ? 138.552 130.752 173.878 1.00 98.78  ?  155 ASN B N   1 
ATOM   3602 C CA  . ASN B 2 152 ? 139.697 129.939 174.255 1.00 98.88  ?  155 ASN B CA  1 
ATOM   3603 C C   . ASN B 2 152 ? 139.456 128.441 174.156 1.00 103.86 ?  155 ASN B C   1 
ATOM   3604 O O   . ASN B 2 152 ? 140.424 127.677 174.193 1.00 107.20 ?  155 ASN B O   1 
ATOM   3605 C CB  . ASN B 2 152 ? 140.136 130.276 175.686 1.00 100.00 ?  155 ASN B CB  1 
ATOM   3606 C CG  . ASN B 2 152 ? 141.545 129.819 175.982 1.00 106.47 ?  155 ASN B CG  1 
ATOM   3607 O OD1 . ASN B 2 152 ? 142.452 130.017 175.177 1.00 104.58 ?  155 ASN B OD1 1 
ATOM   3608 N ND2 . ASN B 2 152 ? 141.736 129.196 177.137 1.00 104.67 ?  155 ASN B ND2 1 
ATOM   3609 N N   . GLN B 2 153 ? 138.209 127.999 174.032 1.00 95.87  ?  156 GLN B N   1 
ATOM   3610 C CA  . GLN B 2 153 ? 137.877 126.582 174.020 1.00 87.56  ?  156 GLN B CA  1 
ATOM   3611 C C   . GLN B 2 153 ? 137.171 126.230 172.722 1.00 88.71  ?  156 GLN B C   1 
ATOM   3612 O O   . GLN B 2 153 ? 136.204 126.893 172.338 1.00 95.99  ?  156 GLN B O   1 
ATOM   3613 C CB  . GLN B 2 153 ? 136.995 126.224 175.214 1.00 84.25  ?  156 GLN B CB  1 
ATOM   3614 C CG  . GLN B 2 153 ? 137.740 126.160 176.525 1.00 86.21  ?  156 GLN B CG  1 
ATOM   3615 C CD  . GLN B 2 153 ? 136.996 125.364 177.569 1.00 100.11 ?  156 GLN B CD  1 
ATOM   3616 O OE1 . GLN B 2 153 ? 135.783 125.498 177.717 1.00 99.95  ?  156 GLN B OE1 1 
ATOM   3617 N NE2 . GLN B 2 153 ? 137.718 124.524 178.297 1.00 99.23  ?  156 GLN B NE2 1 
ATOM   3618 N N   . ILE B 2 154 ? 137.652 125.189 172.052 1.00 71.49  ?  157 ILE B N   1 
ATOM   3619 C CA  . ILE B 2 154 ? 137.031 124.683 170.835 1.00 70.65  ?  157 ILE B CA  1 
ATOM   3620 C C   . ILE B 2 154 ? 137.047 123.163 170.886 1.00 70.23  ?  157 ILE B C   1 
ATOM   3621 O O   . ILE B 2 154 ? 138.034 122.556 171.313 1.00 82.59  ?  157 ILE B O   1 
ATOM   3622 C CB  . ILE B 2 154 ? 137.740 125.219 169.573 1.00 69.56  ?  157 ILE B CB  1 
ATOM   3623 C CG1 . ILE B 2 154 ? 137.001 124.787 168.311 1.00 67.31  ?  157 ILE B CG1 1 
ATOM   3624 C CG2 . ILE B 2 154 ? 139.184 124.771 169.525 1.00 74.64  ?  157 ILE B CG2 1 
ATOM   3625 C CD1 . ILE B 2 154 ? 137.623 125.304 167.051 1.00 71.25  ?  157 ILE B CD1 1 
ATOM   3626 N N   . VAL B 2 155 ? 135.945 122.545 170.474 1.00 67.96  ?  158 VAL B N   1 
ATOM   3627 C CA  . VAL B 2 155 ? 135.813 121.094 170.448 1.00 67.33  ?  158 VAL B CA  1 
ATOM   3628 C C   . VAL B 2 155 ? 135.817 120.644 168.995 1.00 67.26  ?  158 VAL B C   1 
ATOM   3629 O O   . VAL B 2 155 ? 135.063 121.174 168.172 1.00 70.54  ?  158 VAL B O   1 
ATOM   3630 C CB  . VAL B 2 155 ? 134.546 120.622 171.184 1.00 66.48  ?  158 VAL B CB  1 
ATOM   3631 C CG1 . VAL B 2 155 ? 133.333 121.408 170.739 1.00 68.94  ?  158 VAL B CG1 1 
ATOM   3632 C CG2 . VAL B 2 155 ? 134.327 119.143 170.964 1.00 69.08  ?  158 VAL B CG2 1 
ATOM   3633 N N   . THR B 2 156 ? 136.682 119.687 168.677 1.00 73.39  ?  159 THR B N   1 
ATOM   3634 C CA  . THR B 2 156 ? 136.856 119.206 167.317 1.00 70.83  ?  159 THR B CA  1 
ATOM   3635 C C   . THR B 2 156 ? 136.578 117.713 167.244 1.00 79.05  ?  159 THR B C   1 
ATOM   3636 O O   . THR B 2 156 ? 136.884 116.961 168.171 1.00 84.99  ?  159 THR B O   1 
ATOM   3637 C CB  . THR B 2 156 ? 138.270 119.477 166.802 1.00 71.97  ?  159 THR B CB  1 
ATOM   3638 O OG1 . THR B 2 156 ? 139.216 118.790 167.627 1.00 89.97  ?  159 THR B OG1 1 
ATOM   3639 C CG2 . THR B 2 156 ? 138.573 120.957 166.831 1.00 79.14  ?  159 THR B CG2 1 
ATOM   3640 N N   . SER B 2 157 ? 135.992 117.295 166.129 1.00 83.38  ?  160 SER B N   1 
ATOM   3641 C CA  . SER B 2 157 ? 135.760 115.892 165.828 1.00 69.76  ?  160 SER B CA  1 
ATOM   3642 C C   . SER B 2 157 ? 136.648 115.483 164.665 1.00 77.92  ?  160 SER B C   1 
ATOM   3643 O O   . SER B 2 157 ? 136.811 116.237 163.703 1.00 87.65  ?  160 SER B O   1 
ATOM   3644 C CB  . SER B 2 157 ? 134.298 115.636 165.478 1.00 71.82  ?  160 SER B CB  1 
ATOM   3645 O OG  . SER B 2 157 ? 134.061 115.898 164.110 1.00 87.99  ?  160 SER B OG  1 
ATOM   3646 N N   . SER B 2 158 ? 137.223 114.291 164.751 1.00 77.68  ?  161 SER B N   1 
ATOM   3647 C CA  . SER B 2 158 ? 138.185 113.847 163.761 1.00 86.14  ?  161 SER B CA  1 
ATOM   3648 C C   . SER B 2 158 ? 137.826 112.461 163.254 1.00 86.28  ?  161 SER B C   1 
ATOM   3649 O O   . SER B 2 158 ? 137.017 111.745 163.846 1.00 93.28  ?  161 SER B O   1 
ATOM   3650 C CB  . SER B 2 158 ? 139.601 113.836 164.327 1.00 88.01  ?  161 SER B CB  1 
ATOM   3651 O OG  . SER B 2 158 ? 140.283 112.664 163.932 1.00 96.64  ?  161 SER B OG  1 
ATOM   3652 N N   . GLY B 2 159 ? 138.453 112.091 162.144 1.00 78.72  ?  162 GLY B N   1 
ATOM   3653 C CA  . GLY B 2 159 ? 138.277 110.791 161.543 1.00 76.70  ?  162 GLY B CA  1 
ATOM   3654 C C   . GLY B 2 159 ? 139.038 109.675 162.208 1.00 88.65  ?  162 GLY B C   1 
ATOM   3655 O O   . GLY B 2 159 ? 138.962 108.531 161.758 1.00 98.32  ?  162 GLY B O   1 
ATOM   3656 N N   . ASP B 2 160 ? 139.783 109.973 163.271 1.00 90.12  ?  163 ASP B N   1 
ATOM   3657 C CA  . ASP B 2 160 ? 140.442 108.956 164.073 1.00 82.49  ?  163 ASP B CA  1 
ATOM   3658 C C   . ASP B 2 160 ? 139.537 108.409 165.169 1.00 87.51  ?  163 ASP B C   1 
ATOM   3659 O O   . ASP B 2 160 ? 140.038 107.897 166.176 1.00 93.22  ?  163 ASP B O   1 
ATOM   3660 C CB  . ASP B 2 160 ? 141.733 109.513 164.674 1.00 84.96  ?  163 ASP B CB  1 
ATOM   3661 C CG  . ASP B 2 160 ? 141.481 110.526 165.765 1.00 96.20  ?  163 ASP B CG  1 
ATOM   3662 O OD1 . ASP B 2 160 ? 140.442 111.206 165.714 1.00 104.22 ?  163 ASP B OD1 1 
ATOM   3663 O OD2 . ASP B 2 160 ? 142.326 110.650 166.674 1.00 97.97  -1 163 ASP B OD2 1 
ATOM   3664 N N   . THR B 2 161 ? 138.219 108.518 164.989 1.00 85.53  ?  164 THR B N   1 
ATOM   3665 C CA  . THR B 2 161 ? 137.195 107.971 165.876 1.00 90.33  ?  164 THR B CA  1 
ATOM   3666 C C   . THR B 2 161 ? 137.161 108.646 167.241 1.00 90.78  ?  164 THR B C   1 
ATOM   3667 O O   . THR B 2 161 ? 136.584 108.099 168.183 1.00 95.33  ?  164 THR B O   1 
ATOM   3668 C CB  . THR B 2 161 ? 137.350 106.456 166.060 1.00 91.67  ?  164 THR B CB  1 
ATOM   3669 O OG1 . THR B 2 161 ? 138.481 106.186 166.896 1.00 93.27  ?  164 THR B OG1 1 
ATOM   3670 C CG2 . THR B 2 161 ? 137.543 105.765 164.722 1.00 87.99  ?  164 THR B CG2 1 
ATOM   3671 N N   . THR B 2 162 ? 137.760 109.826 167.381 1.00 83.15  ?  165 THR B N   1 
ATOM   3672 C CA  . THR B 2 162 ? 137.777 110.533 168.652 1.00 83.90  ?  165 THR B CA  1 
ATOM   3673 C C   . THR B 2 162 ? 137.367 111.983 168.457 1.00 89.35  ?  165 THR B C   1 
ATOM   3674 O O   . THR B 2 162 ? 137.590 112.576 167.400 1.00 87.59  ?  165 THR B O   1 
ATOM   3675 C CB  . THR B 2 162 ? 139.160 110.500 169.320 1.00 78.52  ?  165 THR B CB  1 
ATOM   3676 O OG1 . THR B 2 162 ? 140.038 111.406 168.645 1.00 83.86  ?  165 THR B OG1 1 
ATOM   3677 C CG2 . THR B 2 162 ? 139.752 109.106 169.284 1.00 82.61  ?  165 THR B CG2 1 
ATOM   3678 N N   . CYS B 2 163 ? 136.759 112.543 169.497 1.00 97.58  ?  166 CYS B N   1 
ATOM   3679 C CA  . CYS B 2 163 ? 136.505 113.969 169.612 1.00 91.25  ?  166 CYS B CA  1 
ATOM   3680 C C   . CYS B 2 163 ? 137.401 114.537 170.703 1.00 92.89  ?  166 CYS B C   1 
ATOM   3681 O O   . CYS B 2 163 ? 137.690 113.867 171.698 1.00 100.73 ?  166 CYS B O   1 
ATOM   3682 C CB  . CYS B 2 163 ? 135.038 114.249 169.944 1.00 88.32  ?  166 CYS B CB  1 
ATOM   3683 S SG  . CYS B 2 163 ? 133.885 113.924 168.602 1.00 98.12  ?  166 CYS B SG  1 
ATOM   3684 N N   . ALA B 2 164 ? 137.854 115.769 170.511 1.00 86.41  ?  167 ALA B N   1 
ATOM   3685 C CA  . ALA B 2 164 ? 138.772 116.394 171.448 1.00 86.89  ?  167 ALA B CA  1 
ATOM   3686 C C   . ALA B 2 164 ? 138.293 117.791 171.803 1.00 86.55  ?  167 ALA B C   1 
ATOM   3687 O O   . ALA B 2 164 ? 137.669 118.476 170.992 1.00 88.17  ?  167 ALA B O   1 
ATOM   3688 C CB  . ALA B 2 164 ? 140.190 116.465 170.881 1.00 83.11  ?  167 ALA B CB  1 
ATOM   3689 N N   . LEU B 2 165 ? 138.592 118.202 173.030 1.00 87.87  ?  168 LEU B N   1 
ATOM   3690 C CA  . LEU B 2 165 ? 138.335 119.553 173.505 1.00 82.70  ?  168 LEU B CA  1 
ATOM   3691 C C   . LEU B 2 165 ? 139.677 120.225 173.748 1.00 84.87  ?  168 LEU B C   1 
ATOM   3692 O O   . LEU B 2 165 ? 140.507 119.703 174.497 1.00 90.65  ?  168 LEU B O   1 
ATOM   3693 C CB  . LEU B 2 165 ? 137.492 119.535 174.779 1.00 85.36  ?  168 LEU B CB  1 
ATOM   3694 C CG  . LEU B 2 165 ? 137.594 120.747 175.701 1.00 87.55  ?  168 LEU B CG  1 
ATOM   3695 C CD1 . LEU B 2 165 ? 136.933 121.944 175.064 1.00 81.63  ?  168 LEU B CD1 1 
ATOM   3696 C CD2 . LEU B 2 165 ? 136.953 120.443 177.036 1.00 90.66  ?  168 LEU B CD2 1 
ATOM   3697 N N   . TRP B 2 166 ? 139.888 121.374 173.119 1.00 87.37  ?  169 TRP B N   1 
ATOM   3698 C CA  . TRP B 2 166 ? 141.187 122.025 173.103 1.00 78.93  ?  169 TRP B CA  1 
ATOM   3699 C C   . TRP B 2 166 ? 141.193 123.268 173.979 1.00 86.25  ?  169 TRP B C   1 
ATOM   3700 O O   . TRP B 2 166 ? 140.150 123.809 174.348 1.00 91.11  ?  169 TRP B O   1 
ATOM   3701 C CB  . TRP B 2 166 ? 141.587 122.413 171.679 1.00 79.92  ?  169 TRP B CB  1 
ATOM   3702 C CG  . TRP B 2 166 ? 141.639 121.273 170.728 1.00 86.73  ?  169 TRP B CG  1 
ATOM   3703 C CD1 . TRP B 2 166 ? 140.592 120.713 170.067 1.00 87.14  ?  169 TRP B CD1 1 
ATOM   3704 C CD2 . TRP B 2 166 ? 142.805 120.558 170.315 1.00 90.03  ?  169 TRP B CD2 1 
ATOM   3705 N NE1 . TRP B 2 166 ? 141.030 119.687 169.271 1.00 90.04  ?  169 TRP B NE1 1 
ATOM   3706 C CE2 . TRP B 2 166 ? 142.387 119.572 169.406 1.00 88.82  ?  169 TRP B CE2 1 
ATOM   3707 C CE3 . TRP B 2 166 ? 144.161 120.654 170.629 1.00 86.47  ?  169 TRP B CE3 1 
ATOM   3708 C CZ2 . TRP B 2 166 ? 143.276 118.690 168.807 1.00 84.15  ?  169 TRP B CZ2 1 
ATOM   3709 C CZ3 . TRP B 2 166 ? 145.040 119.779 170.035 1.00 89.44  ?  169 TRP B CZ3 1 
ATOM   3710 C CH2 . TRP B 2 166 ? 144.595 118.809 169.135 1.00 89.25  ?  169 TRP B CH2 1 
ATOM   3711 N N   . ASP B 2 167 ? 142.402 123.711 174.304 1.00 106.57 ?  170 ASP B N   1 
ATOM   3712 C CA  . ASP B 2 167 ? 142.647 124.985 174.971 1.00 103.26 ?  170 ASP B CA  1 
ATOM   3713 C C   . ASP B 2 167 ? 143.503 125.809 174.016 1.00 102.30 ?  170 ASP B C   1 
ATOM   3714 O O   . ASP B 2 167 ? 144.711 125.582 173.906 1.00 103.18 ?  170 ASP B O   1 
ATOM   3715 C CB  . ASP B 2 167 ? 143.333 124.783 176.316 1.00 104.55 ?  170 ASP B CB  1 
ATOM   3716 C CG  . ASP B 2 167 ? 143.514 126.077 177.078 1.00 109.91 ?  170 ASP B CG  1 
ATOM   3717 O OD1 . ASP B 2 167 ? 142.706 127.005 176.874 1.00 108.04 ?  170 ASP B OD1 1 
ATOM   3718 O OD2 . ASP B 2 167 ? 144.463 126.166 177.881 1.00 110.08 -1 170 ASP B OD2 1 
ATOM   3719 N N   . ILE B 2 168 ? 142.874 126.758 173.320 1.00 90.56  ?  171 ILE B N   1 
ATOM   3720 C CA  . ILE B 2 168 ? 143.561 127.490 172.263 1.00 93.47  ?  171 ILE B CA  1 
ATOM   3721 C C   . ILE B 2 168 ? 144.710 128.334 172.799 1.00 102.13 ?  171 ILE B C   1 
ATOM   3722 O O   . ILE B 2 168 ? 145.642 128.645 172.052 1.00 105.00 ?  171 ILE B O   1 
ATOM   3723 C CB  . ILE B 2 168 ? 142.554 128.351 171.479 1.00 93.39  ?  171 ILE B CB  1 
ATOM   3724 C CG1 . ILE B 2 168 ? 141.328 127.522 171.110 1.00 93.04  ?  171 ILE B CG1 1 
ATOM   3725 C CG2 . ILE B 2 168 ? 143.182 128.898 170.217 1.00 98.86  ?  171 ILE B CG2 1 
ATOM   3726 C CD1 . ILE B 2 168 ? 140.274 128.298 170.370 1.00 93.51  ?  171 ILE B CD1 1 
ATOM   3727 N N   . GLU B 2 169 ? 144.677 128.719 174.075 1.00 114.11 ?  172 GLU B N   1 
ATOM   3728 C CA  . GLU B 2 169 ? 145.797 129.466 174.640 1.00 114.51 ?  172 GLU B CA  1 
ATOM   3729 C C   . GLU B 2 169 ? 147.072 128.632 174.615 1.00 113.56 ?  172 GLU B C   1 
ATOM   3730 O O   . GLU B 2 169 ? 148.107 129.071 174.102 1.00 109.36 ?  172 GLU B O   1 
ATOM   3731 C CB  . GLU B 2 169 ? 145.470 129.900 176.069 1.00 114.80 ?  172 GLU B CB  1 
ATOM   3732 C CG  . GLU B 2 169 ? 146.456 130.853 176.779 1.00 116.38 ?  172 GLU B CG  1 
ATOM   3733 C CD  . GLU B 2 169 ? 147.084 131.937 175.899 1.00 121.95 ?  172 GLU B CD  1 
ATOM   3734 O OE1 . GLU B 2 169 ? 146.949 133.124 176.262 1.00 120.88 ?  172 GLU B OE1 1 
ATOM   3735 O OE2 . GLU B 2 169 ? 147.765 131.632 174.898 1.00 119.34 -1 172 GLU B OE2 1 
ATOM   3736 N N   . THR B 2 170 ? 147.009 127.411 175.145 1.00 110.82 ?  173 THR B N   1 
ATOM   3737 C CA  . THR B 2 170 ? 148.178 126.547 175.223 1.00 112.44 ?  173 THR B CA  1 
ATOM   3738 C C   . THR B 2 170 ? 148.295 125.577 174.057 1.00 111.16 ?  173 THR B C   1 
ATOM   3739 O O   . THR B 2 170 ? 149.386 125.051 173.821 1.00 110.02 ?  173 THR B O   1 
ATOM   3740 C CB  . THR B 2 170 ? 148.164 125.749 176.531 1.00 110.08 ?  173 THR B CB  1 
ATOM   3741 O OG1 . THR B 2 170 ? 147.243 124.660 176.416 1.00 109.18 ?  173 THR B OG1 1 
ATOM   3742 C CG2 . THR B 2 170 ? 147.741 126.637 177.686 1.00 108.82 ?  173 THR B CG2 1 
ATOM   3743 N N   . GLY B 2 171 ? 147.210 125.328 173.329 1.00 111.93 ?  174 GLY B N   1 
ATOM   3744 C CA  . GLY B 2 171 ? 147.264 124.424 172.200 1.00 107.41 ?  174 GLY B CA  1 
ATOM   3745 C C   . GLY B 2 171 ? 147.237 122.957 172.552 1.00 109.14 ?  174 GLY B C   1 
ATOM   3746 O O   . GLY B 2 171 ? 147.559 122.124 171.700 1.00 109.13 ?  174 GLY B O   1 
ATOM   3747 N N   . GLN B 2 172 ? 146.863 122.612 173.777 1.00 109.10 ?  175 GLN B N   1 
ATOM   3748 C CA  . GLN B 2 172 ? 146.822 121.230 174.224 1.00 106.74 ?  175 GLN B CA  1 
ATOM   3749 C C   . GLN B 2 172 ? 145.387 120.726 174.286 1.00 108.81 ?  175 GLN B C   1 
ATOM   3750 O O   . GLN B 2 172 ? 144.429 121.499 174.314 1.00 109.89 ?  175 GLN B O   1 
ATOM   3751 C CB  . GLN B 2 172 ? 147.488 121.085 175.593 1.00 106.91 ?  175 GLN B CB  1 
ATOM   3752 C CG  . GLN B 2 172 ? 148.784 121.859 175.730 1.00 112.12 ?  175 GLN B CG  1 
ATOM   3753 C CD  . GLN B 2 172 ? 149.963 121.125 175.125 1.00 116.24 ?  175 GLN B CD  1 
ATOM   3754 O OE1 . GLN B 2 172 ? 150.144 121.111 173.908 1.00 109.44 ?  175 GLN B OE1 1 
ATOM   3755 N NE2 . GLN B 2 172 ? 150.773 120.506 175.975 1.00 114.27 ?  175 GLN B NE2 1 
ATOM   3756 N N   . GLN B 2 173 ? 145.253 119.403 174.303 1.00 102.05 ?  176 GLN B N   1 
ATOM   3757 C CA  . GLN B 2 173 ? 143.949 118.755 174.383 1.00 95.61  ?  176 GLN B CA  1 
ATOM   3758 C C   . GLN B 2 173 ? 143.539 118.653 175.845 1.00 94.98  ?  176 GLN B C   1 
ATOM   3759 O O   . GLN B 2 173 ? 144.092 117.845 176.597 1.00 95.40  ?  176 GLN B O   1 
ATOM   3760 C CB  . GLN B 2 173 ? 144.003 117.376 173.736 1.00 92.60  ?  176 GLN B CB  1 
ATOM   3761 C CG  . GLN B 2 173 ? 143.567 117.347 172.292 1.00 94.24  ?  176 GLN B CG  1 
ATOM   3762 C CD  . GLN B 2 173 ? 143.590 115.951 171.718 1.00 100.75 ?  176 GLN B CD  1 
ATOM   3763 O OE1 . GLN B 2 173 ? 143.536 114.966 172.451 1.00 100.87 ?  176 GLN B OE1 1 
ATOM   3764 N NE2 . GLN B 2 173 ? 143.663 115.855 170.399 1.00 102.02 ?  176 GLN B NE2 1 
ATOM   3765 N N   . THR B 2 174 ? 142.574 119.475 176.254 1.00 95.38  ?  177 THR B N   1 
ATOM   3766 C CA  . THR B 2 174 ? 142.089 119.413 177.627 1.00 96.26  ?  177 THR B CA  1 
ATOM   3767 C C   . THR B 2 174 ? 141.408 118.080 177.911 1.00 100.47 ?  177 THR B C   1 
ATOM   3768 O O   . THR B 2 174 ? 141.648 117.460 178.953 1.00 99.89  ?  177 THR B O   1 
ATOM   3769 C CB  . THR B 2 174 ? 141.131 120.572 177.895 1.00 100.40 ?  177 THR B CB  1 
ATOM   3770 O OG1 . THR B 2 174 ? 141.854 121.807 177.852 1.00 100.04 ?  177 THR B OG1 1 
ATOM   3771 C CG2 . THR B 2 174 ? 140.483 120.425 179.258 1.00 96.16  ?  177 THR B CG2 1 
ATOM   3772 N N   . THR B 2 175 ? 140.564 117.619 176.992 1.00 102.76 ?  178 THR B N   1 
ATOM   3773 C CA  . THR B 2 175 ? 139.820 116.382 177.164 1.00 100.10 ?  178 THR B CA  1 
ATOM   3774 C C   . THR B 2 175 ? 139.770 115.639 175.840 1.00 100.53 ?  178 THR B C   1 
ATOM   3775 O O   . THR B 2 175 ? 139.774 116.248 174.769 1.00 102.43 ?  178 THR B O   1 
ATOM   3776 C CB  . THR B 2 175 ? 138.394 116.648 177.665 1.00 104.91 ?  178 THR B CB  1 
ATOM   3777 O OG1 . THR B 2 175 ? 138.418 117.688 178.650 1.00 105.41 ?  178 THR B OG1 1 
ATOM   3778 C CG2 . THR B 2 175 ? 137.797 115.396 178.279 1.00 103.30 ?  178 THR B CG2 1 
ATOM   3779 N N   . THR B 2 176 ? 139.725 114.314 175.923 1.00 100.21 ?  179 THR B N   1 
ATOM   3780 C CA  . THR B 2 176 ? 139.589 113.455 174.757 1.00 97.16  ?  179 THR B CA  1 
ATOM   3781 C C   . THR B 2 176 ? 138.378 112.558 174.951 1.00 101.19 ?  179 THR B C   1 
ATOM   3782 O O   . THR B 2 176 ? 138.221 111.940 176.008 1.00 105.65 ?  179 THR B O   1 
ATOM   3783 C CB  . THR B 2 176 ? 140.847 112.615 174.536 1.00 99.23  ?  179 THR B CB  1 
ATOM   3784 O OG1 . THR B 2 176 ? 142.004 113.440 174.706 1.00 103.91 ?  179 THR B OG1 1 
ATOM   3785 C CG2 . THR B 2 176 ? 140.857 112.039 173.138 1.00 99.85  ?  179 THR B CG2 1 
ATOM   3786 N N   . PHE B 2 177 ? 137.524 112.496 173.939 1.00 96.66  ?  180 PHE B N   1 
ATOM   3787 C CA  . PHE B 2 177 ? 136.282 111.732 173.990 1.00 95.79  ?  180 PHE B CA  1 
ATOM   3788 C C   . PHE B 2 177 ? 136.433 110.525 173.073 1.00 101.34 ?  180 PHE B C   1 
ATOM   3789 O O   . PHE B 2 177 ? 136.284 110.639 171.854 1.00 104.71 ?  180 PHE B O   1 
ATOM   3790 C CB  . PHE B 2 177 ? 135.100 112.604 173.585 1.00 90.88  ?  180 PHE B CB  1 
ATOM   3791 C CG  . PHE B 2 177 ? 135.024 113.901 174.333 1.00 92.91  ?  180 PHE B CG  1 
ATOM   3792 C CD1 . PHE B 2 177 ? 134.461 113.956 175.592 1.00 96.25  ?  180 PHE B CD1 1 
ATOM   3793 C CD2 . PHE B 2 177 ? 135.517 115.065 173.778 1.00 94.40  ?  180 PHE B CD2 1 
ATOM   3794 C CE1 . PHE B 2 177 ? 134.390 115.144 176.279 1.00 92.94  ?  180 PHE B CE1 1 
ATOM   3795 C CE2 . PHE B 2 177 ? 135.448 116.256 174.464 1.00 94.39  ?  180 PHE B CE2 1 
ATOM   3796 C CZ  . PHE B 2 177 ? 134.884 116.294 175.715 1.00 92.97  ?  180 PHE B CZ  1 
ATOM   3797 N N   . THR B 2 178 ? 136.718 109.367 173.663 1.00 102.61 ?  181 THR B N   1 
ATOM   3798 C CA  . THR B 2 178 ? 137.018 108.145 172.921 1.00 103.82 ?  181 THR B CA  1 
ATOM   3799 C C   . THR B 2 178 ? 135.974 107.087 173.259 1.00 101.45 ?  181 THR B C   1 
ATOM   3800 O O   . THR B 2 178 ? 136.094 106.383 174.263 1.00 104.98 ?  181 THR B O   1 
ATOM   3801 C CB  . THR B 2 178 ? 138.418 107.646 173.244 1.00 105.35 ?  181 THR B CB  1 
ATOM   3802 O OG1 . THR B 2 178 ? 138.513 107.376 174.647 1.00 105.11 ?  181 THR B OG1 1 
ATOM   3803 C CG2 . THR B 2 178 ? 139.452 108.684 172.869 1.00 101.03 ?  181 THR B CG2 1 
ATOM   3804 N N   . GLY B 2 179 ? 134.943 106.984 172.428 1.00 90.42  ?  182 GLY B N   1 
ATOM   3805 C CA  . GLY B 2 179 ? 134.003 105.890 172.553 1.00 90.19  ?  182 GLY B CA  1 
ATOM   3806 C C   . GLY B 2 179 ? 133.415 105.435 171.235 1.00 92.15  ?  182 GLY B C   1 
ATOM   3807 O O   . GLY B 2 179 ? 132.512 104.596 171.211 1.00 99.74  ?  182 GLY B O   1 
ATOM   3808 N N   . HIS B 2 180 ? 133.930 105.959 170.130 1.00 87.32  ?  183 HIS B N   1 
ATOM   3809 C CA  . HIS B 2 180 ? 133.381 105.702 168.810 1.00 85.23  ?  183 HIS B CA  1 
ATOM   3810 C C   . HIS B 2 180 ? 134.263 104.665 168.131 1.00 91.40  ?  183 HIS B C   1 
ATOM   3811 O O   . HIS B 2 180 ? 135.489 104.680 168.272 1.00 101.83 ?  183 HIS B O   1 
ATOM   3812 C CB  . HIS B 2 180 ? 133.315 106.961 167.941 1.00 92.51  ?  183 HIS B CB  1 
ATOM   3813 C CG  . HIS B 2 180 ? 132.037 107.727 168.074 1.00 89.50  ?  183 HIS B CG  1 
ATOM   3814 N ND1 . HIS B 2 180 ? 130.803 107.164 167.841 1.00 87.73  ?  183 HIS B ND1 1 
ATOM   3815 C CD2 . HIS B 2 180 ? 131.804 109.018 168.405 1.00 90.04  ?  183 HIS B CD2 1 
ATOM   3816 C CE1 . HIS B 2 180 ? 129.864 108.074 168.028 1.00 86.33  ?  183 HIS B CE1 1 
ATOM   3817 N NE2 . HIS B 2 180 ? 130.445 109.207 168.372 1.00 76.02  ?  183 HIS B NE2 1 
ATOM   3818 N N   . THR B 2 181 ? 133.629 103.760 167.392 1.00 93.73  ?  184 THR B N   1 
ATOM   3819 C CA  . THR B 2 181 ? 134.341 102.759 166.613 1.00 95.57  ?  184 THR B CA  1 
ATOM   3820 C C   . THR B 2 181 ? 134.460 103.130 165.142 1.00 94.77  ?  184 THR B C   1 
ATOM   3821 O O   . THR B 2 181 ? 135.014 102.352 164.362 1.00 94.47  ?  184 THR B O   1 
ATOM   3822 C CB  . THR B 2 181 ? 133.658 101.396 166.752 1.00 95.55  ?  184 THR B CB  1 
ATOM   3823 O OG1 . THR B 2 181 ? 132.311 101.484 166.276 1.00 99.08  ?  184 THR B OG1 1 
ATOM   3824 C CG2 . THR B 2 181 ? 133.645 100.961 168.204 1.00 91.49  ?  184 THR B CG2 1 
ATOM   3825 N N   . GLY B 2 182 ? 133.951 104.297 164.745 1.00 94.69  ?  185 GLY B N   1 
ATOM   3826 C CA  . GLY B 2 182 ? 134.097 104.768 163.386 1.00 92.71  ?  185 GLY B CA  1 
ATOM   3827 C C   . GLY B 2 182 ? 134.454 106.240 163.380 1.00 91.05  ?  185 GLY B C   1 
ATOM   3828 O O   . GLY B 2 182 ? 134.443 106.901 164.418 1.00 102.13 ?  185 GLY B O   1 
ATOM   3829 N N   . ASP B 2 183 ? 134.782 106.742 162.193 1.00 89.46  ?  186 ASP B N   1 
ATOM   3830 C CA  . ASP B 2 183 ? 135.181 108.137 162.070 1.00 87.31  ?  186 ASP B CA  1 
ATOM   3831 C C   . ASP B 2 183 ? 134.035 109.051 162.469 1.00 89.30  ?  186 ASP B C   1 
ATOM   3832 O O   . ASP B 2 183 ? 132.907 108.886 162.003 1.00 99.42  ?  186 ASP B O   1 
ATOM   3833 C CB  . ASP B 2 183 ? 135.613 108.446 160.641 1.00 92.01  ?  186 ASP B CB  1 
ATOM   3834 C CG  . ASP B 2 183 ? 136.359 107.306 160.001 1.00 107.49 ?  186 ASP B CG  1 
ATOM   3835 O OD1 . ASP B 2 183 ? 137.192 106.677 160.683 1.00 106.81 ?  186 ASP B OD1 1 
ATOM   3836 O OD2 . ASP B 2 183 ? 136.116 107.044 158.810 1.00 109.12 -1 186 ASP B OD2 1 
ATOM   3837 N N   . VAL B 2 184 ? 134.330 110.025 163.321 1.00 79.87  ?  187 VAL B N   1 
ATOM   3838 C CA  . VAL B 2 184 ? 133.327 110.997 163.739 1.00 81.59  ?  187 VAL B CA  1 
ATOM   3839 C C   . VAL B 2 184 ? 133.202 112.054 162.652 1.00 76.40  ?  187 VAL B C   1 
ATOM   3840 O O   . VAL B 2 184 ? 134.172 112.746 162.330 1.00 90.56  ?  187 VAL B O   1 
ATOM   3841 C CB  . VAL B 2 184 ? 133.692 111.627 165.087 1.00 72.56  ?  187 VAL B CB  1 
ATOM   3842 C CG1 . VAL B 2 184 ? 132.534 112.432 165.609 1.00 76.44  ?  187 VAL B CG1 1 
ATOM   3843 C CG2 . VAL B 2 184 ? 134.065 110.550 166.074 1.00 69.59  ?  187 VAL B CG2 1 
ATOM   3844 N N   . MET B 2 185 ? 132.006 112.180 162.083 1.00 67.46  ?  188 MET B N   1 
ATOM   3845 C CA  . MET B 2 185 ? 131.802 113.038 160.928 1.00 77.09  ?  188 MET B CA  1 
ATOM   3846 C C   . MET B 2 185 ? 131.111 114.352 161.252 1.00 80.19  ?  188 MET B C   1 
ATOM   3847 O O   . MET B 2 185 ? 131.140 115.265 160.422 1.00 83.80  ?  188 MET B O   1 
ATOM   3848 C CB  . MET B 2 185 ? 130.985 112.301 159.861 1.00 78.27  ?  188 MET B CB  1 
ATOM   3849 C CG  . MET B 2 185 ? 131.586 110.987 159.416 1.00 78.56  ?  188 MET B CG  1 
ATOM   3850 S SD  . MET B 2 185 ? 133.130 111.220 158.529 1.00 107.55 ?  188 MET B SD  1 
ATOM   3851 C CE  . MET B 2 185 ? 132.677 112.549 157.422 1.00 86.04  ?  188 MET B CE  1 
ATOM   3852 N N   . SER B 2 186 ? 130.496 114.478 162.421 1.00 81.46  ?  189 SER B N   1 
ATOM   3853 C CA  . SER B 2 186 ? 129.733 115.673 162.733 1.00 79.18  ?  189 SER B CA  1 
ATOM   3854 C C   . SER B 2 186 ? 129.830 115.966 164.220 1.00 80.51  ?  189 SER B C   1 
ATOM   3855 O O   . SER B 2 186 ? 130.310 115.152 165.010 1.00 85.71  ?  189 SER B O   1 
ATOM   3856 C CB  . SER B 2 186 ? 128.272 115.534 162.308 1.00 85.70  ?  189 SER B CB  1 
ATOM   3857 O OG  . SER B 2 186 ? 127.739 116.793 161.939 1.00 86.20  ?  189 SER B OG  1 
ATOM   3858 N N   . LEU B 2 187 ? 129.357 117.151 164.587 1.00 83.69  ?  190 LEU B N   1 
ATOM   3859 C CA  . LEU B 2 187 ? 129.449 117.648 165.949 1.00 74.65  ?  190 LEU B CA  1 
ATOM   3860 C C   . LEU B 2 187 ? 128.408 118.741 166.125 1.00 75.78  ?  190 LEU B C   1 
ATOM   3861 O O   . LEU B 2 187 ? 128.162 119.519 165.202 1.00 80.72  ?  190 LEU B O   1 
ATOM   3862 C CB  . LEU B 2 187 ? 130.853 118.184 166.232 1.00 75.28  ?  190 LEU B CB  1 
ATOM   3863 C CG  . LEU B 2 187 ? 131.269 118.433 167.673 1.00 80.12  ?  190 LEU B CG  1 
ATOM   3864 C CD1 . LEU B 2 187 ? 132.618 117.814 167.923 1.00 72.70  ?  190 LEU B CD1 1 
ATOM   3865 C CD2 . LEU B 2 187 ? 131.312 119.920 167.935 1.00 86.71  ?  190 LEU B CD2 1 
ATOM   3866 N N   . SER B 2 188 ? 127.797 118.793 167.303 1.00 67.25  ?  191 SER B N   1 
ATOM   3867 C CA  . SER B 2 188 ? 126.816 119.829 167.592 1.00 70.93  ?  191 SER B CA  1 
ATOM   3868 C C   . SER B 2 188 ? 126.862 120.156 169.072 1.00 78.05  ?  191 SER B C   1 
ATOM   3869 O O   . SER B 2 188 ? 126.734 119.262 169.911 1.00 87.13  ?  191 SER B O   1 
ATOM   3870 C CB  . SER B 2 188 ? 125.408 119.390 167.192 1.00 77.47  ?  191 SER B CB  1 
ATOM   3871 O OG  . SER B 2 188 ? 124.551 120.507 167.057 1.00 78.59  ?  191 SER B OG  1 
ATOM   3872 N N   . LEU B 2 189 ? 127.035 121.433 169.385 1.00 87.52  ?  192 LEU B N   1 
ATOM   3873 C CA  . LEU B 2 189 ? 127.128 121.886 170.762 1.00 86.15  ?  192 LEU B CA  1 
ATOM   3874 C C   . LEU B 2 189 ? 125.743 122.179 171.317 1.00 82.49  ?  192 LEU B C   1 
ATOM   3875 O O   . LEU B 2 189 ? 124.892 122.746 170.629 1.00 88.39  ?  192 LEU B O   1 
ATOM   3876 C CB  . LEU B 2 189 ? 127.997 123.137 170.855 1.00 86.42  ?  192 LEU B CB  1 
ATOM   3877 C CG  . LEU B 2 189 ? 129.468 122.923 171.178 1.00 83.34  ?  192 LEU B CG  1 
ATOM   3878 C CD1 . LEU B 2 189 ? 130.207 124.231 171.045 1.00 84.05  ?  192 LEU B CD1 1 
ATOM   3879 C CD2 . LEU B 2 189 ? 129.615 122.365 172.574 1.00 78.05  ?  192 LEU B CD2 1 
ATOM   3880 N N   . ALA B 2 190 ? 125.526 121.792 172.569 1.00 82.64  ?  193 ALA B N   1 
ATOM   3881 C CA  . ALA B 2 190 ? 124.277 122.104 173.232 1.00 82.75  ?  193 ALA B CA  1 
ATOM   3882 C C   . ALA B 2 190 ? 124.146 123.615 173.405 1.00 92.99  ?  193 ALA B C   1 
ATOM   3883 O O   . ALA B 2 190 ? 125.150 124.324 173.495 1.00 98.70  ?  193 ALA B O   1 
ATOM   3884 C CB  . ALA B 2 190 ? 124.203 121.416 174.590 1.00 84.33  ?  193 ALA B CB  1 
ATOM   3885 N N   . PRO B 2 191 ? 122.916 124.135 173.431 1.00 99.62  ?  194 PRO B N   1 
ATOM   3886 C CA  . PRO B 2 191 ? 122.748 125.587 173.605 1.00 97.78  ?  194 PRO B CA  1 
ATOM   3887 C C   . PRO B 2 191 ? 123.390 126.124 174.873 1.00 100.91 ?  194 PRO B C   1 
ATOM   3888 O O   . PRO B 2 191 ? 123.901 127.250 174.870 1.00 100.09 ?  194 PRO B O   1 
ATOM   3889 C CB  . PRO B 2 191 ? 121.225 125.756 173.614 1.00 98.69  ?  194 PRO B CB  1 
ATOM   3890 C CG  . PRO B 2 191 ? 120.720 124.595 172.837 1.00 96.19  ?  194 PRO B CG  1 
ATOM   3891 C CD  . PRO B 2 191 ? 121.638 123.459 173.157 1.00 95.95  ?  194 PRO B CD  1 
ATOM   3892 N N   . ASP B 2 192 ? 123.385 125.352 175.958 1.00 104.11 ?  195 ASP B N   1 
ATOM   3893 C CA  . ASP B 2 192 ? 124.067 125.767 177.177 1.00 101.66 ?  195 ASP B CA  1 
ATOM   3894 C C   . ASP B 2 192 ? 125.548 125.414 177.178 1.00 105.83 ?  195 ASP B C   1 
ATOM   3895 O O   . ASP B 2 192 ? 126.240 125.723 178.153 1.00 106.34 ?  195 ASP B O   1 
ATOM   3896 C CB  . ASP B 2 192 ? 123.383 125.156 178.404 1.00 110.13 ?  195 ASP B CB  1 
ATOM   3897 C CG  . ASP B 2 192 ? 123.553 123.649 178.492 1.00 116.32 ?  195 ASP B CG  1 
ATOM   3898 O OD1 . ASP B 2 192 ? 124.002 123.024 177.509 1.00 114.54 ?  195 ASP B OD1 1 
ATOM   3899 O OD2 . ASP B 2 192 ? 123.232 123.084 179.557 1.00 112.23 -1 195 ASP B OD2 1 
ATOM   3900 N N   . THR B 2 193 ? 126.042 124.782 176.112 1.00 106.15 ?  196 THR B N   1 
ATOM   3901 C CA  . THR B 2 193 ? 127.440 124.378 175.944 1.00 104.96 ?  196 THR B CA  1 
ATOM   3902 C C   . THR B 2 193 ? 127.933 123.466 177.062 1.00 102.52 ?  196 THR B C   1 
ATOM   3903 O O   . THR B 2 193 ? 129.142 123.318 177.254 1.00 99.80  ?  196 THR B O   1 
ATOM   3904 C CB  . THR B 2 193 ? 128.380 125.585 175.807 1.00 110.90 ?  196 THR B CB  1 
ATOM   3905 O OG1 . THR B 2 193 ? 128.030 126.606 176.749 1.00 115.79 ?  196 THR B OG1 1 
ATOM   3906 C CG2 . THR B 2 193 ? 128.306 126.157 174.402 1.00 103.48 ?  196 THR B CG2 1 
ATOM   3907 N N   . ARG B 2 194 ? 127.023 122.842 177.806 1.00 107.69 ?  197 ARG B N   1 
ATOM   3908 C CA  . ARG B 2 194 ? 127.399 121.859 178.811 1.00 109.95 ?  197 ARG B CA  1 
ATOM   3909 C C   . ARG B 2 194 ? 127.538 120.456 178.241 1.00 109.33 ?  197 ARG B C   1 
ATOM   3910 O O   . ARG B 2 194 ? 128.114 119.588 178.904 1.00 106.86 ?  197 ARG B O   1 
ATOM   3911 C CB  . ARG B 2 194 ? 126.370 121.839 179.946 1.00 114.44 ?  197 ARG B CB  1 
ATOM   3912 C CG  . ARG B 2 194 ? 126.290 123.125 180.745 1.00 111.26 ?  197 ARG B CG  1 
ATOM   3913 C CD  . ARG B 2 194 ? 127.674 123.602 181.146 1.00 115.63 ?  197 ARG B CD  1 
ATOM   3914 N NE  . ARG B 2 194 ? 128.224 122.849 182.267 1.00 120.87 ?  197 ARG B NE  1 
ATOM   3915 C CZ  . ARG B 2 194 ? 127.754 122.879 183.508 1.00 121.02 ?  197 ARG B CZ  1 
ATOM   3916 N NH1 . ARG B 2 194 ? 126.727 123.642 183.843 1.00 118.72 1  197 ARG B NH1 1 
ATOM   3917 N NH2 . ARG B 2 194 ? 128.339 122.130 184.439 1.00 116.89 ?  197 ARG B NH2 1 
ATOM   3918 N N   . LEU B 2 195 ? 127.025 120.215 177.038 1.00 93.53  ?  198 LEU B N   1 
ATOM   3919 C CA  . LEU B 2 195 ? 127.081 118.912 176.399 1.00 84.61  ?  198 LEU B CA  1 
ATOM   3920 C C   . LEU B 2 195 ? 127.301 119.112 174.910 1.00 88.66  ?  198 LEU B C   1 
ATOM   3921 O O   . LEU B 2 195 ? 127.187 120.223 174.392 1.00 100.13 ?  198 LEU B O   1 
ATOM   3922 C CB  . LEU B 2 195 ? 125.794 118.109 176.627 1.00 85.87  ?  198 LEU B CB  1 
ATOM   3923 C CG  . LEU B 2 195 ? 125.319 117.871 178.060 1.00 90.89  ?  198 LEU B CG  1 
ATOM   3924 C CD1 . LEU B 2 195 ? 123.824 117.624 178.076 1.00 84.17  ?  198 LEU B CD1 1 
ATOM   3925 C CD2 . LEU B 2 195 ? 126.057 116.713 178.695 1.00 91.66  ?  198 LEU B CD2 1 
ATOM   3926 N N   . PHE B 2 196 ? 127.628 118.024 174.221 1.00 79.80  ?  199 PHE B N   1 
ATOM   3927 C CA  . PHE B 2 196 ? 127.645 118.039 172.768 1.00 79.42  ?  199 PHE B CA  1 
ATOM   3928 C C   . PHE B 2 196 ? 127.440 116.622 172.259 1.00 86.62  ?  199 PHE B C   1 
ATOM   3929 O O   . PHE B 2 196 ? 127.762 115.650 172.944 1.00 90.96  ?  199 PHE B O   1 
ATOM   3930 C CB  . PHE B 2 196 ? 128.939 118.656 172.219 1.00 74.73  ?  199 PHE B CB  1 
ATOM   3931 C CG  . PHE B 2 196 ? 130.110 117.721 172.193 1.00 80.02  ?  199 PHE B CG  1 
ATOM   3932 C CD1 . PHE B 2 196 ? 130.891 117.543 173.314 1.00 82.87  ?  199 PHE B CD1 1 
ATOM   3933 C CD2 . PHE B 2 196 ? 130.449 117.047 171.038 1.00 79.12  ?  199 PHE B CD2 1 
ATOM   3934 C CE1 . PHE B 2 196 ? 131.973 116.699 173.291 1.00 80.72  ?  199 PHE B CE1 1 
ATOM   3935 C CE2 . PHE B 2 196 ? 131.529 116.200 171.012 1.00 82.58  ?  199 PHE B CE2 1 
ATOM   3936 C CZ  . PHE B 2 196 ? 132.291 116.026 172.138 1.00 79.97  ?  199 PHE B CZ  1 
ATOM   3937 N N   . VAL B 2 197 ? 126.884 116.517 171.057 1.00 78.52  ?  200 VAL B N   1 
ATOM   3938 C CA  . VAL B 2 197 ? 126.617 115.233 170.425 1.00 69.42  ?  200 VAL B CA  1 
ATOM   3939 C C   . VAL B 2 197 ? 127.513 115.090 169.207 1.00 75.64  ?  200 VAL B C   1 
ATOM   3940 O O   . VAL B 2 197 ? 127.820 116.064 168.514 1.00 82.82  ?  200 VAL B O   1 
ATOM   3941 C CB  . VAL B 2 197 ? 125.137 115.071 170.026 1.00 69.96  ?  200 VAL B CB  1 
ATOM   3942 C CG1 . VAL B 2 197 ? 124.288 114.824 171.249 1.00 74.86  ?  200 VAL B CG1 1 
ATOM   3943 C CG2 . VAL B 2 197 ? 124.655 116.292 169.274 1.00 69.15  ?  200 VAL B CG2 1 
ATOM   3944 N N   . SER B 2 198 ? 127.936 113.858 168.950 1.00 67.07  ?  201 SER B N   1 
ATOM   3945 C CA  . SER B 2 198 ? 128.799 113.545 167.823 1.00 70.52  ?  201 SER B CA  1 
ATOM   3946 C C   . SER B 2 198 ? 128.217 112.365 167.066 1.00 71.32  ?  201 SER B C   1 
ATOM   3947 O O   . SER B 2 198 ? 127.821 111.369 167.676 1.00 80.56  ?  201 SER B O   1 
ATOM   3948 C CB  . SER B 2 198 ? 130.218 113.222 168.290 1.00 75.85  ?  201 SER B CB  1 
ATOM   3949 O OG  . SER B 2 198 ? 130.213 112.163 169.228 1.00 82.45  ?  201 SER B OG  1 
ATOM   3950 N N   . GLY B 2 199 ? 128.162 112.480 165.745 1.00 77.67  ?  202 GLY B N   1 
ATOM   3951 C CA  . GLY B 2 199 ? 127.718 111.383 164.913 1.00 81.28  ?  202 GLY B CA  1 
ATOM   3952 C C   . GLY B 2 199 ? 128.862 110.790 164.123 1.00 86.63  ?  202 GLY B C   1 
ATOM   3953 O O   . GLY B 2 199 ? 129.531 111.503 163.374 1.00 92.79  ?  202 GLY B O   1 
ATOM   3954 N N   . ALA B 2 200 ? 129.101 109.496 164.276 1.00 77.85  ?  203 ALA B N   1 
ATOM   3955 C CA  . ALA B 2 200 ? 130.247 108.847 163.664 1.00 73.52  ?  203 ALA B CA  1 
ATOM   3956 C C   . ALA B 2 200 ? 129.803 107.929 162.533 1.00 82.45  ?  203 ALA B C   1 
ATOM   3957 O O   . ALA B 2 200 ? 128.621 107.833 162.198 1.00 89.39  ?  203 ALA B O   1 
ATOM   3958 C CB  . ALA B 2 200 ? 131.047 108.076 164.711 1.00 79.95  ?  203 ALA B CB  1 
ATOM   3959 N N   . CYS B 2 201 ? 130.781 107.246 161.941 1.00 92.54  ?  204 CYS B N   1 
ATOM   3960 C CA  . CYS B 2 201 ? 130.528 106.340 160.830 1.00 91.47  ?  204 CYS B CA  1 
ATOM   3961 C C   . CYS B 2 201 ? 130.058 104.965 161.278 1.00 92.08  ?  204 CYS B C   1 
ATOM   3962 O O   . CYS B 2 201 ? 129.716 104.141 160.426 1.00 97.44  ?  204 CYS B O   1 
ATOM   3963 C CB  . CYS B 2 201 ? 131.787 106.196 159.975 1.00 93.58  ?  204 CYS B CB  1 
ATOM   3964 S SG  . CYS B 2 201 ? 131.941 107.423 158.666 1.00 109.37 ?  204 CYS B SG  1 
ATOM   3965 N N   . ASP B 2 202 ? 130.033 104.692 162.580 1.00 91.11  ?  205 ASP B N   1 
ATOM   3966 C CA  . ASP B 2 202 ? 129.495 103.442 163.094 1.00 98.39  ?  205 ASP B CA  1 
ATOM   3967 C C   . ASP B 2 202 ? 127.986 103.503 163.301 1.00 98.13  ?  205 ASP B C   1 
ATOM   3968 O O   . ASP B 2 202 ? 127.440 102.693 164.057 1.00 89.18  ?  205 ASP B O   1 
ATOM   3969 C CB  . ASP B 2 202 ? 130.195 103.060 164.398 1.00 94.22  ?  205 ASP B CB  1 
ATOM   3970 C CG  . ASP B 2 202 ? 130.056 104.118 165.465 1.00 99.78  ?  205 ASP B CG  1 
ATOM   3971 O OD1 . ASP B 2 202 ? 129.679 105.255 165.127 1.00 105.06 ?  205 ASP B OD1 1 
ATOM   3972 O OD2 . ASP B 2 202 ? 130.320 103.815 166.646 1.00 100.96 -1 205 ASP B OD2 1 
ATOM   3973 N N   . ALA B 2 203 ? 127.313 104.454 162.650 1.00 89.52  ?  206 ALA B N   1 
ATOM   3974 C CA  . ALA B 2 203 ? 125.857 104.582 162.679 1.00 87.29  ?  206 ALA B CA  1 
ATOM   3975 C C   . ALA B 2 203 ? 125.328 104.833 164.086 1.00 94.57  ?  206 ALA B C   1 
ATOM   3976 O O   . ALA B 2 203 ? 124.198 104.463 164.409 1.00 97.85  ?  206 ALA B O   1 
ATOM   3977 C CB  . ALA B 2 203 ? 125.180 103.353 162.070 1.00 91.35  ?  206 ALA B CB  1 
ATOM   3978 N N   . SER B 2 204 ? 126.129 105.471 164.933 1.00 91.06  ?  207 SER B N   1 
ATOM   3979 C CA  . SER B 2 204 ? 125.732 105.763 166.301 1.00 88.27  ?  207 SER B CA  1 
ATOM   3980 C C   . SER B 2 204 ? 126.081 107.200 166.646 1.00 84.38  ?  207 SER B C   1 
ATOM   3981 O O   . SER B 2 204 ? 127.112 107.721 166.212 1.00 86.87  ?  207 SER B O   1 
ATOM   3982 C CB  . SER B 2 204 ? 126.408 104.818 167.292 1.00 83.96  ?  207 SER B CB  1 
ATOM   3983 O OG  . SER B 2 204 ? 127.633 105.359 167.747 1.00 83.86  ?  207 SER B OG  1 
ATOM   3984 N N   . ALA B 2 205 ? 125.213 107.835 167.426 1.00 77.58  ?  208 ALA B N   1 
ATOM   3985 C CA  . ALA B 2 205 ? 125.444 109.168 167.955 1.00 71.49  ?  208 ALA B CA  1 
ATOM   3986 C C   . ALA B 2 205 ? 125.602 109.079 169.463 1.00 76.48  ?  208 ALA B C   1 
ATOM   3987 O O   . ALA B 2 205 ? 124.907 108.301 170.122 1.00 83.18  ?  208 ALA B O   1 
ATOM   3988 C CB  . ALA B 2 205 ? 124.295 110.113 167.602 1.00 71.49  ?  208 ALA B CB  1 
ATOM   3989 N N   . LYS B 2 206 ? 126.519 109.868 170.008 1.00 70.96  ?  209 LYS B N   1 
ATOM   3990 C CA  . LYS B 2 206 ? 126.841 109.807 171.422 1.00 72.91  ?  209 LYS B CA  1 
ATOM   3991 C C   . LYS B 2 206 ? 126.728 111.191 172.038 1.00 78.39  ?  209 LYS B C   1 
ATOM   3992 O O   . LYS B 2 206 ? 127.024 112.198 171.396 1.00 85.95  ?  209 LYS B O   1 
ATOM   3993 C CB  . LYS B 2 206 ? 128.245 109.249 171.646 1.00 73.07  ?  209 LYS B CB  1 
ATOM   3994 C CG  . LYS B 2 206 ? 128.354 107.772 171.351 1.00 76.33  ?  209 LYS B CG  1 
ATOM   3995 C CD  . LYS B 2 206 ? 129.742 107.248 171.609 1.00 73.63  ?  209 LYS B CD  1 
ATOM   3996 C CE  . LYS B 2 206 ? 129.773 105.747 171.449 1.00 77.37  ?  209 LYS B CE  1 
ATOM   3997 N NZ  . LYS B 2 206 ? 129.828 105.063 172.765 1.00 79.85  1  209 LYS B NZ  1 
ATOM   3998 N N   . LEU B 2 207 ? 126.289 111.227 173.291 1.00 83.79  ?  210 LEU B N   1 
ATOM   3999 C CA  . LEU B 2 207 ? 126.163 112.461 174.053 1.00 84.57  ?  210 LEU B CA  1 
ATOM   4000 C C   . LEU B 2 207 ? 127.294 112.520 175.069 1.00 86.30  ?  210 LEU B C   1 
ATOM   4001 O O   . LEU B 2 207 ? 127.434 111.616 175.898 1.00 93.69  ?  210 LEU B O   1 
ATOM   4002 C CB  . LEU B 2 207 ? 124.806 112.536 174.748 1.00 86.63  ?  210 LEU B CB  1 
ATOM   4003 C CG  . LEU B 2 207 ? 124.588 113.710 175.698 1.00 86.42  ?  210 LEU B CG  1 
ATOM   4004 C CD1 . LEU B 2 207 ? 124.439 114.997 174.919 1.00 88.04  ?  210 LEU B CD1 1 
ATOM   4005 C CD2 . LEU B 2 207 ? 123.376 113.465 176.569 1.00 88.82  ?  210 LEU B CD2 1 
ATOM   4006 N N   . TRP B 2 208 ? 128.091 113.581 175.008 1.00 82.00  ?  211 TRP B N   1 
ATOM   4007 C CA  . TRP B 2 208 ? 129.262 113.734 175.854 1.00 82.45  ?  211 TRP B CA  1 
ATOM   4008 C C   . TRP B 2 208 ? 129.075 114.883 176.832 1.00 89.92  ?  211 TRP B C   1 
ATOM   4009 O O   . TRP B 2 208 ? 128.313 115.818 176.581 1.00 99.26  ?  211 TRP B O   1 
ATOM   4010 C CB  . TRP B 2 208 ? 130.518 113.993 175.023 1.00 84.93  ?  211 TRP B CB  1 
ATOM   4011 C CG  . TRP B 2 208 ? 130.722 113.052 173.892 1.00 88.20  ?  211 TRP B CG  1 
ATOM   4012 C CD1 . TRP B 2 208 ? 130.253 113.185 172.623 1.00 84.05  ?  211 TRP B CD1 1 
ATOM   4013 C CD2 . TRP B 2 208 ? 131.468 111.835 173.920 1.00 82.51  ?  211 TRP B CD2 1 
ATOM   4014 N NE1 . TRP B 2 208 ? 130.656 112.123 171.857 1.00 83.39  ?  211 TRP B NE1 1 
ATOM   4015 C CE2 . TRP B 2 208 ? 131.404 111.278 172.632 1.00 81.49  ?  211 TRP B CE2 1 
ATOM   4016 C CE3 . TRP B 2 208 ? 132.181 111.160 174.911 1.00 81.33  ?  211 TRP B CE3 1 
ATOM   4017 C CZ2 . TRP B 2 208 ? 132.023 110.080 172.311 1.00 87.41  ?  211 TRP B CZ2 1 
ATOM   4018 C CZ3 . TRP B 2 208 ? 132.795 109.974 174.589 1.00 86.15  ?  211 TRP B CZ3 1 
ATOM   4019 C CH2 . TRP B 2 208 ? 132.713 109.445 173.301 1.00 90.54  ?  211 TRP B CH2 1 
ATOM   4020 N N   . ASP B 2 209 ? 129.788 114.804 177.950 1.00 109.52 ?  212 ASP B N   1 
ATOM   4021 C CA  . ASP B 2 209 ? 129.868 115.882 178.924 1.00 112.02 ?  212 ASP B CA  1 
ATOM   4022 C C   . ASP B 2 209 ? 131.219 116.555 178.719 1.00 113.59 ?  212 ASP B C   1 
ATOM   4023 O O   . ASP B 2 209 ? 132.261 115.912 178.867 1.00 117.84 ?  212 ASP B O   1 
ATOM   4024 C CB  . ASP B 2 209 ? 129.711 115.335 180.346 1.00 106.64 ?  212 ASP B CB  1 
ATOM   4025 C CG  . ASP B 2 209 ? 130.101 116.335 181.439 1.00 117.86 ?  212 ASP B CG  1 
ATOM   4026 O OD1 . ASP B 2 209 ? 130.536 117.469 181.152 1.00 124.23 ?  212 ASP B OD1 1 
ATOM   4027 O OD2 . ASP B 2 209 ? 129.966 115.968 182.624 1.00 117.29 -1 212 ASP B OD2 1 
ATOM   4028 N N   . VAL B 2 210 ? 131.198 117.843 178.376 1.00 99.30  ?  213 VAL B N   1 
ATOM   4029 C CA  . VAL B 2 210 ? 132.444 118.546 178.087 1.00 97.55  ?  213 VAL B CA  1 
ATOM   4030 C C   . VAL B 2 210 ? 133.258 118.770 179.352 1.00 104.04 ?  213 VAL B C   1 
ATOM   4031 O O   . VAL B 2 210 ? 134.494 118.806 179.302 1.00 107.71 ?  213 VAL B O   1 
ATOM   4032 C CB  . VAL B 2 210 ? 132.155 119.877 177.372 1.00 99.51  ?  213 VAL B CB  1 
ATOM   4033 C CG1 . VAL B 2 210 ? 131.789 119.634 175.927 1.00 100.93 ?  213 VAL B CG1 1 
ATOM   4034 C CG2 . VAL B 2 210 ? 131.046 120.623 178.078 1.00 104.65 ?  213 VAL B CG2 1 
ATOM   4035 N N   . ARG B 2 211 ? 132.594 118.929 180.499 1.00 121.02 ?  214 ARG B N   1 
ATOM   4036 C CA  . ARG B 2 211 ? 133.284 119.387 181.702 1.00 120.10 ?  214 ARG B CA  1 
ATOM   4037 C C   . ARG B 2 211 ? 134.334 118.387 182.169 1.00 121.52 ?  214 ARG B C   1 
ATOM   4038 O O   . ARG B 2 211 ? 135.431 118.781 182.579 1.00 123.28 ?  214 ARG B O   1 
ATOM   4039 C CB  . ARG B 2 211 ? 132.273 119.667 182.812 1.00 118.58 ?  214 ARG B CB  1 
ATOM   4040 C CG  . ARG B 2 211 ? 131.969 121.145 182.994 1.00 117.59 ?  214 ARG B CG  1 
ATOM   4041 C CD  . ARG B 2 211 ? 131.320 121.722 181.746 1.00 119.91 ?  214 ARG B CD  1 
ATOM   4042 N NE  . ARG B 2 211 ? 131.048 123.149 181.865 1.00 123.50 ?  214 ARG B NE  1 
ATOM   4043 C CZ  . ARG B 2 211 ? 131.108 124.010 180.857 1.00 124.60 ?  214 ARG B CZ  1 
ATOM   4044 N NH1 . ARG B 2 211 ? 131.441 123.623 179.637 1.00 123.34 1  214 ARG B NH1 1 
ATOM   4045 N NH2 . ARG B 2 211 ? 130.823 125.289 181.079 1.00 120.92 ?  214 ARG B NH2 1 
ATOM   4046 N N   . GLU B 2 212 ? 134.025 117.098 182.123 1.00 126.13 ?  215 GLU B N   1 
ATOM   4047 C CA  . GLU B 2 212 ? 134.986 116.082 182.530 1.00 129.23 ?  215 GLU B CA  1 
ATOM   4048 C C   . GLU B 2 212 ? 135.250 115.037 181.459 1.00 130.60 ?  215 GLU B C   1 
ATOM   4049 O O   . GLU B 2 212 ? 136.391 114.597 181.303 1.00 133.48 ?  215 GLU B O   1 
ATOM   4050 C CB  . GLU B 2 212 ? 134.514 115.399 183.817 1.00 129.82 ?  215 GLU B CB  1 
ATOM   4051 C CG  . GLU B 2 212 ? 133.018 115.227 183.906 1.00 128.66 ?  215 GLU B CG  1 
ATOM   4052 C CD  . GLU B 2 212 ? 132.590 113.851 183.476 1.00 133.67 ?  215 GLU B CD  1 
ATOM   4053 O OE1 . GLU B 2 212 ? 133.483 113.016 183.224 1.00 131.21 ?  215 GLU B OE1 1 
ATOM   4054 O OE2 . GLU B 2 212 ? 131.370 113.601 183.397 1.00 136.01 -1 215 GLU B OE2 1 
ATOM   4055 N N   . GLY B 2 213 ? 134.228 114.623 180.717 1.00 126.41 ?  216 GLY B N   1 
ATOM   4056 C CA  . GLY B 2 213 ? 134.437 113.800 179.543 1.00 125.31 ?  216 GLY B CA  1 
ATOM   4057 C C   . GLY B 2 213 ? 134.082 112.339 179.706 1.00 125.36 ?  216 GLY B C   1 
ATOM   4058 O O   . GLY B 2 213 ? 134.879 111.547 180.215 1.00 129.87 ?  216 GLY B O   1 
ATOM   4059 N N   . MET B 2 214 ? 132.885 111.973 179.255 1.00 118.31 ?  217 MET B N   1 
ATOM   4060 C CA  . MET B 2 214 ? 132.440 110.589 179.186 1.00 120.43 ?  217 MET B CA  1 
ATOM   4061 C C   . MET B 2 214 ? 131.158 110.554 178.375 1.00 118.17 ?  217 MET B C   1 
ATOM   4062 O O   . MET B 2 214 ? 130.356 111.486 178.445 1.00 119.64 ?  217 MET B O   1 
ATOM   4063 C CB  . MET B 2 214 ? 132.195 109.980 180.574 1.00 120.00 ?  217 MET B CB  1 
ATOM   4064 C CG  . MET B 2 214 ? 131.767 110.965 181.642 1.00 123.66 ?  217 MET B CG  1 
ATOM   4065 S SD  . MET B 2 214 ? 129.987 111.227 181.701 1.00 138.44 ?  217 MET B SD  1 
ATOM   4066 C CE  . MET B 2 214 ? 129.444 109.707 182.475 1.00 121.36 ?  217 MET B CE  1 
ATOM   4067 N N   . CYS B 2 215 ? 130.974 109.485 177.610 1.00 108.03 ?  218 CYS B N   1 
ATOM   4068 C CA  . CYS B 2 215 ? 129.756 109.320 176.828 1.00 104.80 ?  218 CYS B CA  1 
ATOM   4069 C C   . CYS B 2 215 ? 128.597 109.047 177.775 1.00 106.18 ?  218 CYS B C   1 
ATOM   4070 O O   . CYS B 2 215 ? 128.534 107.985 178.401 1.00 110.90 ?  218 CYS B O   1 
ATOM   4071 C CB  . CYS B 2 215 ? 129.925 108.189 175.821 1.00 104.34 ?  218 CYS B CB  1 
ATOM   4072 S SG  . CYS B 2 215 ? 128.404 107.678 175.015 1.00 111.39 ?  218 CYS B SG  1 
ATOM   4073 N N   . ARG B 2 216 ? 127.686 110.012 177.901 1.00 103.63 ?  219 ARG B N   1 
ATOM   4074 C CA  . ARG B 2 216 ? 126.556 109.836 178.804 1.00 103.95 ?  219 ARG B CA  1 
ATOM   4075 C C   . ARG B 2 216 ? 125.526 108.875 178.225 1.00 109.60 ?  219 ARG B C   1 
ATOM   4076 O O   . ARG B 2 216 ? 124.995 108.022 178.944 1.00 113.02 ?  219 ARG B O   1 
ATOM   4077 C CB  . ARG B 2 216 ? 125.916 111.186 179.116 1.00 103.05 ?  219 ARG B CB  1 
ATOM   4078 C CG  . ARG B 2 216 ? 126.730 112.044 180.060 1.00 110.37 ?  219 ARG B CG  1 
ATOM   4079 C CD  . ARG B 2 216 ? 125.837 112.925 180.914 1.00 111.63 ?  219 ARG B CD  1 
ATOM   4080 N NE  . ARG B 2 216 ? 126.595 113.652 181.925 1.00 113.39 ?  219 ARG B NE  1 
ATOM   4081 C CZ  . ARG B 2 216 ? 127.084 113.108 183.032 1.00 112.03 ?  219 ARG B CZ  1 
ATOM   4082 N NH1 . ARG B 2 216 ? 126.900 111.829 183.314 1.00 111.00 1  219 ARG B NH1 1 
ATOM   4083 N NH2 . ARG B 2 216 ? 127.773 113.868 183.878 1.00 110.39 ?  219 ARG B NH2 1 
ATOM   4084 N N   . GLN B 2 217 ? 125.227 109.000 176.934 1.00 99.38  ?  220 GLN B N   1 
ATOM   4085 C CA  . GLN B 2 217 ? 124.242 108.154 176.280 1.00 95.50  ?  220 GLN B CA  1 
ATOM   4086 C C   . GLN B 2 217 ? 124.700 107.850 174.863 1.00 98.03  ?  220 GLN B C   1 
ATOM   4087 O O   . GLN B 2 217 ? 125.457 108.615 174.263 1.00 104.33 ?  220 GLN B O   1 
ATOM   4088 C CB  . GLN B 2 217 ? 122.859 108.815 176.245 1.00 93.63  ?  220 GLN B CB  1 
ATOM   4089 C CG  . GLN B 2 217 ? 122.247 109.047 177.612 1.00 102.35 ?  220 GLN B CG  1 
ATOM   4090 C CD  . GLN B 2 217 ? 121.171 110.105 177.595 1.00 104.74 ?  220 GLN B CD  1 
ATOM   4091 O OE1 . GLN B 2 217 ? 120.609 110.415 176.550 1.00 103.47 ?  220 GLN B OE1 1 
ATOM   4092 N NE2 . GLN B 2 217 ? 120.883 110.674 178.757 1.00 105.04 ?  220 GLN B NE2 1 
ATOM   4093 N N   . THR B 2 218 ? 124.231 106.723 174.334 1.00 92.02  ?  221 THR B N   1 
ATOM   4094 C CA  . THR B 2 218 ? 124.524 106.310 172.969 1.00 89.88  ?  221 THR B CA  1 
ATOM   4095 C C   . THR B 2 218 ? 123.212 106.055 172.248 1.00 91.38  ?  221 THR B C   1 
ATOM   4096 O O   . THR B 2 218 ? 122.340 105.355 172.771 1.00 102.30 ?  221 THR B O   1 
ATOM   4097 C CB  . THR B 2 218 ? 125.395 105.053 172.938 1.00 95.67  ?  221 THR B CB  1 
ATOM   4098 O OG1 . THR B 2 218 ? 126.558 105.255 173.748 1.00 98.35  ?  221 THR B OG1 1 
ATOM   4099 C CG2 . THR B 2 218 ? 125.824 104.743 171.519 1.00 92.25  ?  221 THR B CG2 1 
ATOM   4100 N N   . PHE B 2 219 ? 123.074 106.619 171.054 1.00 83.14  ?  222 PHE B N   1 
ATOM   4101 C CA  . PHE B 2 219 ? 121.839 106.544 170.288 1.00 84.01  ?  222 PHE B CA  1 
ATOM   4102 C C   . PHE B 2 219 ? 122.091 105.792 168.993 1.00 86.61  ?  222 PHE B C   1 
ATOM   4103 O O   . PHE B 2 219 ? 122.998 106.142 168.233 1.00 95.23  ?  222 PHE B O   1 
ATOM   4104 C CB  . PHE B 2 219 ? 121.296 107.940 169.989 1.00 84.11  ?  222 PHE B CB  1 
ATOM   4105 C CG  . PHE B 2 219 ? 121.082 108.778 171.210 1.00 89.05  ?  222 PHE B CG  1 
ATOM   4106 C CD1 . PHE B 2 219 ? 122.103 109.560 171.715 1.00 86.01  ?  222 PHE B CD1 1 
ATOM   4107 C CD2 . PHE B 2 219 ? 119.858 108.788 171.850 1.00 86.06  ?  222 PHE B CD2 1 
ATOM   4108 C CE1 . PHE B 2 219 ? 121.909 110.330 172.835 1.00 86.36  ?  222 PHE B CE1 1 
ATOM   4109 C CE2 . PHE B 2 219 ? 119.660 109.558 172.970 1.00 84.53  ?  222 PHE B CE2 1 
ATOM   4110 C CZ  . PHE B 2 219 ? 120.686 110.329 173.463 1.00 89.72  ?  222 PHE B CZ  1 
ATOM   4111 N N   . THR B 2 220 ? 121.286 104.768 168.743 1.00 89.53  ?  223 THR B N   1 
ATOM   4112 C CA  . THR B 2 220 ? 121.396 103.953 167.547 1.00 94.60  ?  223 THR B CA  1 
ATOM   4113 C C   . THR B 2 220 ? 120.073 103.964 166.795 1.00 96.10  ?  223 THR B C   1 
ATOM   4114 O O   . THR B 2 220 ? 119.060 104.478 167.273 1.00 102.66 ?  223 THR B O   1 
ATOM   4115 C CB  . THR B 2 220 ? 121.796 102.515 167.893 1.00 100.65 ?  223 THR B CB  1 
ATOM   4116 O OG1 . THR B 2 220 ? 120.865 101.978 168.840 1.00 101.78 ?  223 THR B OG1 1 
ATOM   4117 C CG2 . THR B 2 220 ? 123.194 102.480 168.488 1.00 96.01  ?  223 THR B CG2 1 
ATOM   4118 N N   . GLY B 2 221 ? 120.092 103.381 165.603 1.00 92.89  ?  224 GLY B N   1 
ATOM   4119 C CA  . GLY B 2 221 ? 118.906 103.316 164.779 1.00 91.94  ?  224 GLY B CA  1 
ATOM   4120 C C   . GLY B 2 221 ? 119.212 103.547 163.317 1.00 96.70  ?  224 GLY B C   1 
ATOM   4121 O O   . GLY B 2 221 ? 118.495 103.058 162.440 1.00 98.10  ?  224 GLY B O   1 
ATOM   4122 N N   . HIS B 2 222 ? 120.278 104.289 163.043 1.00 89.59  ?  225 HIS B N   1 
ATOM   4123 C CA  . HIS B 2 222 ? 120.688 104.521 161.669 1.00 84.95  ?  225 HIS B CA  1 
ATOM   4124 C C   . HIS B 2 222 ? 121.321 103.265 161.086 1.00 92.33  ?  225 HIS B C   1 
ATOM   4125 O O   . HIS B 2 222 ? 121.907 102.447 161.799 1.00 95.68  ?  225 HIS B O   1 
ATOM   4126 C CB  . HIS B 2 222 ? 121.668 105.687 161.593 1.00 87.56  ?  225 HIS B CB  1 
ATOM   4127 C CG  . HIS B 2 222 ? 121.009 107.017 161.400 1.00 89.77  ?  225 HIS B CG  1 
ATOM   4128 N ND1 . HIS B 2 222 ? 120.322 107.348 160.254 1.00 88.18  ?  225 HIS B ND1 1 
ATOM   4129 C CD2 . HIS B 2 222 ? 120.933 108.099 162.208 1.00 90.62  ?  225 HIS B CD2 1 
ATOM   4130 C CE1 . HIS B 2 222 ? 119.857 108.578 160.362 1.00 81.78  ?  225 HIS B CE1 1 
ATOM   4131 N NE2 . HIS B 2 222 ? 120.211 109.055 161.540 1.00 84.11  ?  225 HIS B NE2 1 
ATOM   4132 N N   . GLU B 2 223 ? 121.191 103.113 159.772 1.00 104.86 ?  226 GLU B N   1 
ATOM   4133 C CA  . GLU B 2 223 ? 121.702 101.947 159.069 1.00 101.78 ?  226 GLU B CA  1 
ATOM   4134 C C   . GLU B 2 223 ? 123.016 102.208 158.349 1.00 101.61 ?  226 GLU B C   1 
ATOM   4135 O O   . GLU B 2 223 ? 123.538 101.299 157.700 1.00 106.09 ?  226 GLU B O   1 
ATOM   4136 C CB  . GLU B 2 223 ? 120.660 101.443 158.067 1.00 102.24 ?  226 GLU B CB  1 
ATOM   4137 C CG  . GLU B 2 223 ? 119.683 100.441 158.649 1.00 106.78 ?  226 GLU B CG  1 
ATOM   4138 C CD  . GLU B 2 223 ? 118.241 100.863 158.468 1.00 115.79 ?  226 GLU B CD  1 
ATOM   4139 O OE1 . GLU B 2 223 ? 117.957 101.624 157.520 1.00 114.19 ?  226 GLU B OE1 1 
ATOM   4140 O OE2 . GLU B 2 223 ? 117.389 100.436 159.275 1.00 113.90 -1 226 GLU B OE2 1 
ATOM   4141 N N   . SER B 2 224 ? 123.564 103.413 158.446 1.00 96.24  ?  227 SER B N   1 
ATOM   4142 C CA  . SER B 2 224 ? 124.786 103.756 157.732 1.00 96.91  ?  227 SER B CA  1 
ATOM   4143 C C   . SER B 2 224 ? 125.460 104.912 158.461 1.00 96.90  ?  227 SER B C   1 
ATOM   4144 O O   . SER B 2 224 ? 125.015 105.336 159.531 1.00 98.74  ?  227 SER B O   1 
ATOM   4145 C CB  . SER B 2 224 ? 124.485 104.095 156.270 1.00 101.59 ?  227 SER B CB  1 
ATOM   4146 O OG  . SER B 2 224 ? 125.621 103.876 155.455 1.00 107.70 ?  227 SER B OG  1 
ATOM   4147 N N   . ASP B 2 225 ? 126.538 105.425 157.873 1.00 94.70  ?  228 ASP B N   1 
ATOM   4148 C CA  . ASP B 2 225 ? 127.322 106.470 158.515 1.00 89.62  ?  228 ASP B CA  1 
ATOM   4149 C C   . ASP B 2 225 ? 126.494 107.731 158.704 1.00 94.45  ?  228 ASP B C   1 
ATOM   4150 O O   . ASP B 2 225 ? 125.767 108.156 157.805 1.00 103.15 ?  228 ASP B O   1 
ATOM   4151 C CB  . ASP B 2 225 ? 128.560 106.790 157.681 1.00 92.63  ?  228 ASP B CB  1 
ATOM   4152 C CG  . ASP B 2 225 ? 129.146 105.566 157.015 1.00 104.01 ?  228 ASP B CG  1 
ATOM   4153 O OD1 . ASP B 2 225 ? 129.256 104.516 157.679 1.00 105.50 ?  228 ASP B OD1 1 
ATOM   4154 O OD2 . ASP B 2 225 ? 129.504 105.655 155.825 1.00 102.61 -1 228 ASP B OD2 1 
ATOM   4155 N N   . ILE B 2 226 ? 126.616 108.335 159.881 1.00 85.16  ?  229 ILE B N   1 
ATOM   4156 C CA  . ILE B 2 226 ? 125.939 109.587 160.190 1.00 79.37  ?  229 ILE B CA  1 
ATOM   4157 C C   . ILE B 2 226 ? 126.833 110.733 159.742 1.00 78.37  ?  229 ILE B C   1 
ATOM   4158 O O   . ILE B 2 226 ? 127.961 110.875 160.223 1.00 80.19  ?  229 ILE B O   1 
ATOM   4159 C CB  . ILE B 2 226 ? 125.619 109.691 161.687 1.00 76.65  ?  229 ILE B CB  1 
ATOM   4160 C CG1 . ILE B 2 226 ? 124.500 108.725 162.059 1.00 70.09  ?  229 ILE B CG1 1 
ATOM   4161 C CG2 . ILE B 2 226 ? 125.231 111.104 162.048 1.00 79.37  ?  229 ILE B CG2 1 
ATOM   4162 C CD1 . ILE B 2 226 ? 124.172 108.729 163.519 1.00 72.97  ?  229 ILE B CD1 1 
ATOM   4163 N N   . ASN B 2 227 ? 126.335 111.551 158.819 1.00 78.13  ?  230 ASN B N   1 
ATOM   4164 C CA  . ASN B 2 227 ? 127.117 112.651 158.274 1.00 76.64  ?  230 ASN B CA  1 
ATOM   4165 C C   . ASN B 2 227 ? 126.832 113.983 158.942 1.00 84.01  ?  230 ASN B C   1 
ATOM   4166 O O   . ASN B 2 227 ? 127.695 114.864 158.930 1.00 88.87  ?  230 ASN B O   1 
ATOM   4167 C CB  . ASN B 2 227 ? 126.860 112.796 156.773 1.00 73.61  ?  230 ASN B CB  1 
ATOM   4168 C CG  . ASN B 2 227 ? 127.124 111.525 156.012 1.00 83.71  ?  230 ASN B CG  1 
ATOM   4169 O OD1 . ASN B 2 227 ? 128.128 110.854 156.231 1.00 94.38  ?  230 ASN B OD1 1 
ATOM   4170 N ND2 . ASN B 2 227 ? 126.221 111.184 155.105 1.00 78.92  ?  230 ASN B ND2 1 
ATOM   4171 N N   . ALA B 2 228 ? 125.646 114.155 159.516 1.00 78.54  ?  231 ALA B N   1 
ATOM   4172 C CA  . ALA B 2 228 ? 125.244 115.430 160.080 1.00 61.74  ?  231 ALA B CA  1 
ATOM   4173 C C   . ALA B 2 228 ? 124.518 115.214 161.395 1.00 69.33  ?  231 ALA B C   1 
ATOM   4174 O O   . ALA B 2 228 ? 123.864 114.191 161.604 1.00 80.81  ?  231 ALA B O   1 
ATOM   4175 C CB  . ALA B 2 228 ? 124.344 116.200 159.121 1.00 68.06  ?  231 ALA B CB  1 
ATOM   4176 N N   . ILE B 2 229 ? 124.635 116.201 162.278 1.00 68.22  ?  232 ILE B N   1 
ATOM   4177 C CA  . ILE B 2 229 ? 123.966 116.180 163.569 1.00 68.90  ?  232 ILE B CA  1 
ATOM   4178 C C   . ILE B 2 229 ? 123.700 117.621 163.975 1.00 70.22  ?  232 ILE B C   1 
ATOM   4179 O O   . ILE B 2 229 ? 124.475 118.526 163.660 1.00 73.64  ?  232 ILE B O   1 
ATOM   4180 C CB  . ILE B 2 229 ? 124.802 115.416 164.625 1.00 61.10  ?  232 ILE B CB  1 
ATOM   4181 C CG1 . ILE B 2 229 ? 123.923 114.951 165.780 1.00 65.21  ?  232 ILE B CG1 1 
ATOM   4182 C CG2 . ILE B 2 229 ? 125.940 116.259 165.140 1.00 67.15  ?  232 ILE B CG2 1 
ATOM   4183 C CD1 . ILE B 2 229 ? 124.502 113.792 166.532 1.00 69.02  ?  232 ILE B CD1 1 
ATOM   4184 N N   . CYS B 2 230 ? 122.574 117.839 164.646 1.00 72.08  ?  233 CYS B N   1 
ATOM   4185 C CA  . CYS B 2 230 ? 122.185 119.179 165.057 1.00 67.84  ?  233 CYS B CA  1 
ATOM   4186 C C   . CYS B 2 230 ? 121.307 119.089 166.290 1.00 70.15  ?  233 CYS B C   1 
ATOM   4187 O O   . CYS B 2 230 ? 120.447 118.215 166.381 1.00 79.13  ?  233 CYS B O   1 
ATOM   4188 C CB  . CYS B 2 230 ? 121.442 119.917 163.941 1.00 72.35  ?  233 CYS B CB  1 
ATOM   4189 S SG  . CYS B 2 230 ? 121.180 121.670 164.269 1.00 98.94  ?  233 CYS B SG  1 
ATOM   4190 N N   . PHE B 2 231 ? 121.524 120.003 167.228 1.00 67.28  ?  234 PHE B N   1 
ATOM   4191 C CA  . PHE B 2 231 ? 120.742 120.039 168.453 1.00 67.31  ?  234 PHE B CA  1 
ATOM   4192 C C   . PHE B 2 231 ? 119.422 120.764 168.235 1.00 70.52  ?  234 PHE B C   1 
ATOM   4193 O O   . PHE B 2 231 ? 119.360 121.779 167.538 1.00 73.67  ?  234 PHE B O   1 
ATOM   4194 C CB  . PHE B 2 231 ? 121.530 120.730 169.563 1.00 69.84  ?  234 PHE B CB  1 
ATOM   4195 C CG  . PHE B 2 231 ? 121.973 119.811 170.658 1.00 67.40  ?  234 PHE B CG  1 
ATOM   4196 C CD1 . PHE B 2 231 ? 121.062 119.293 171.553 1.00 69.46  ?  234 PHE B CD1 1 
ATOM   4197 C CD2 . PHE B 2 231 ? 123.302 119.477 170.801 1.00 63.02  ?  234 PHE B CD2 1 
ATOM   4198 C CE1 . PHE B 2 231 ? 121.468 118.454 172.563 1.00 68.42  ?  234 PHE B CE1 1 
ATOM   4199 C CE2 . PHE B 2 231 ? 123.710 118.640 171.810 1.00 72.39  ?  234 PHE B CE2 1 
ATOM   4200 C CZ  . PHE B 2 231 ? 122.793 118.128 172.690 1.00 67.64  ?  234 PHE B CZ  1 
ATOM   4201 N N   . PHE B 2 232 ? 118.365 120.233 168.838 1.00 79.31  ?  235 PHE B N   1 
ATOM   4202 C CA  . PHE B 2 232 ? 117.100 120.941 168.897 1.00 75.89  ?  235 PHE B CA  1 
ATOM   4203 C C   . PHE B 2 232 ? 117.283 122.230 169.696 1.00 87.94  ?  235 PHE B C   1 
ATOM   4204 O O   . PHE B 2 232 ? 118.072 122.271 170.644 1.00 94.71  ?  235 PHE B O   1 
ATOM   4205 C CB  . PHE B 2 232 ? 116.037 120.059 169.546 1.00 72.03  ?  235 PHE B CB  1 
ATOM   4206 C CG  . PHE B 2 232 ? 114.630 120.517 169.312 1.00 85.13  ?  235 PHE B CG  1 
ATOM   4207 C CD1 . PHE B 2 232 ? 114.008 120.304 168.100 1.00 86.50  ?  235 PHE B CD1 1 
ATOM   4208 C CD2 . PHE B 2 232 ? 113.922 121.148 170.315 1.00 84.55  ?  235 PHE B CD2 1 
ATOM   4209 C CE1 . PHE B 2 232 ? 112.716 120.721 167.892 1.00 82.10  ?  235 PHE B CE1 1 
ATOM   4210 C CE2 . PHE B 2 232 ? 112.631 121.567 170.110 1.00 79.69  ?  235 PHE B CE2 1 
ATOM   4211 C CZ  . PHE B 2 232 ? 112.027 121.352 168.899 1.00 79.26  ?  235 PHE B CZ  1 
ATOM   4212 N N   . PRO B 2 233 ? 116.580 123.305 169.328 1.00 79.73  ?  236 PRO B N   1 
ATOM   4213 C CA  . PRO B 2 233 ? 116.750 124.569 170.060 1.00 78.06  ?  236 PRO B CA  1 
ATOM   4214 C C   . PRO B 2 233 ? 116.467 124.450 171.544 1.00 80.30  ?  236 PRO B C   1 
ATOM   4215 O O   . PRO B 2 233 ? 117.063 125.183 172.342 1.00 85.24  ?  236 PRO B O   1 
ATOM   4216 C CB  . PRO B 2 233 ? 115.753 125.503 169.368 1.00 79.82  ?  236 PRO B CB  1 
ATOM   4217 C CG  . PRO B 2 233 ? 115.629 124.956 168.003 1.00 78.69  ?  236 PRO B CG  1 
ATOM   4218 C CD  . PRO B 2 233 ? 115.733 123.472 168.138 1.00 81.55  ?  236 PRO B CD  1 
ATOM   4219 N N   . ASN B 2 234 ? 115.572 123.545 171.937 1.00 92.46  ?  237 ASN B N   1 
ATOM   4220 C CA  . ASN B 2 234 ? 115.322 123.308 173.353 1.00 90.99  ?  237 ASN B CA  1 
ATOM   4221 C C   . ASN B 2 234 ? 116.562 122.779 174.059 1.00 90.71  ?  237 ASN B C   1 
ATOM   4222 O O   . ASN B 2 234 ? 116.750 123.027 175.254 1.00 92.70  ?  237 ASN B O   1 
ATOM   4223 C CB  . ASN B 2 234 ? 114.161 122.328 173.508 1.00 91.22  ?  237 ASN B CB  1 
ATOM   4224 C CG  . ASN B 2 234 ? 113.710 122.178 174.935 1.00 99.35  ?  237 ASN B CG  1 
ATOM   4225 O OD1 . ASN B 2 234 ? 113.908 123.071 175.757 1.00 104.64 ?  237 ASN B OD1 1 
ATOM   4226 N ND2 . ASN B 2 234 ? 113.090 121.047 175.242 1.00 97.16  ?  237 ASN B ND2 1 
ATOM   4227 N N   . GLY B 2 235 ? 117.422 122.063 173.339 1.00 91.79  ?  238 GLY B N   1 
ATOM   4228 C CA  . GLY B 2 235 ? 118.568 121.414 173.932 1.00 90.19  ?  238 GLY B CA  1 
ATOM   4229 C C   . GLY B 2 235 ? 118.298 120.035 174.486 1.00 95.06  ?  238 GLY B C   1 
ATOM   4230 O O   . GLY B 2 235 ? 119.224 119.406 175.012 1.00 93.10  ?  238 GLY B O   1 
ATOM   4231 N N   . ASN B 2 236 ? 117.063 119.547 174.391 1.00 95.47  ?  239 ASN B N   1 
ATOM   4232 C CA  . ASN B 2 236 ? 116.684 118.244 174.917 1.00 91.69  ?  239 ASN B CA  1 
ATOM   4233 C C   . ASN B 2 236 ? 116.464 117.210 173.823 1.00 91.40  ?  239 ASN B C   1 
ATOM   4234 O O   . ASN B 2 236 ? 115.920 116.138 174.100 1.00 98.55  ?  239 ASN B O   1 
ATOM   4235 C CB  . ASN B 2 236 ? 115.427 118.367 175.777 1.00 95.67  ?  239 ASN B CB  1 
ATOM   4236 C CG  . ASN B 2 236 ? 115.708 118.980 177.129 1.00 102.74 ?  239 ASN B CG  1 
ATOM   4237 O OD1 . ASN B 2 236 ? 116.733 118.700 177.748 1.00 102.88 ?  239 ASN B OD1 1 
ATOM   4238 N ND2 . ASN B 2 236 ? 114.796 119.819 177.598 1.00 97.95  ?  239 ASN B ND2 1 
ATOM   4239 N N   . ALA B 2 237 ? 116.862 117.506 172.592 1.00 84.85  ?  240 ALA B N   1 
ATOM   4240 C CA  . ALA B 2 237 ? 116.709 116.576 171.484 1.00 81.04  ?  240 ALA B CA  1 
ATOM   4241 C C   . ALA B 2 237 ? 117.715 116.956 170.411 1.00 87.25  ?  240 ALA B C   1 
ATOM   4242 O O   . ALA B 2 237 ? 118.323 118.026 170.456 1.00 95.44  ?  240 ALA B O   1 
ATOM   4243 C CB  . ALA B 2 237 ? 115.281 116.588 170.936 1.00 78.53  ?  240 ALA B CB  1 
ATOM   4244 N N   . PHE B 2 238 ? 117.900 116.057 169.450 1.00 73.28  ?  241 PHE B N   1 
ATOM   4245 C CA  . PHE B 2 238 ? 118.777 116.356 168.329 1.00 70.97  ?  241 PHE B CA  1 
ATOM   4246 C C   . PHE B 2 238 ? 118.368 115.513 167.133 1.00 70.41  ?  241 PHE B C   1 
ATOM   4247 O O   . PHE B 2 238 ? 117.695 114.490 167.270 1.00 78.42  ?  241 PHE B O   1 
ATOM   4248 C CB  . PHE B 2 238 ? 120.251 116.130 168.685 1.00 65.73  ?  241 PHE B CB  1 
ATOM   4249 C CG  . PHE B 2 238 ? 120.611 114.699 168.931 1.00 73.29  ?  241 PHE B CG  1 
ATOM   4250 C CD1 . PHE B 2 238 ? 120.411 114.127 170.169 1.00 75.92  ?  241 PHE B CD1 1 
ATOM   4251 C CD2 . PHE B 2 238 ? 121.170 113.930 167.930 1.00 69.57  ?  241 PHE B CD2 1 
ATOM   4252 C CE1 . PHE B 2 238 ? 120.748 112.818 170.400 1.00 69.04  ?  241 PHE B CE1 1 
ATOM   4253 C CE2 . PHE B 2 238 ? 121.507 112.619 168.158 1.00 67.48  ?  241 PHE B CE2 1 
ATOM   4254 C CZ  . PHE B 2 238 ? 121.297 112.064 169.393 1.00 65.98  ?  241 PHE B CZ  1 
ATOM   4255 N N   . ALA B 2 239 ? 118.779 115.966 165.955 1.00 66.83  ?  242 ALA B N   1 
ATOM   4256 C CA  . ALA B 2 239 ? 118.492 115.291 164.702 1.00 59.12  ?  242 ALA B CA  1 
ATOM   4257 C C   . ALA B 2 239 ? 119.790 114.834 164.057 1.00 71.57  ?  242 ALA B C   1 
ATOM   4258 O O   . ALA B 2 239 ? 120.822 115.499 164.164 1.00 80.77  ?  242 ALA B O   1 
ATOM   4259 C CB  . ALA B 2 239 ? 117.730 116.199 163.740 1.00 70.15  ?  242 ALA B CB  1 
ATOM   4260 N N   . THR B 2 240 ? 119.731 113.686 163.392 1.00 73.01  ?  243 THR B N   1 
ATOM   4261 C CA  . THR B 2 240 ? 120.879 113.108 162.714 1.00 70.55  ?  243 THR B CA  1 
ATOM   4262 C C   . THR B 2 240 ? 120.546 112.881 161.251 1.00 76.05  ?  243 THR B C   1 
ATOM   4263 O O   . THR B 2 240 ? 119.445 112.439 160.920 1.00 82.20  ?  243 THR B O   1 
ATOM   4264 C CB  . THR B 2 240 ? 121.294 111.779 163.346 1.00 81.66  ?  243 THR B CB  1 
ATOM   4265 O OG1 . THR B 2 240 ? 120.130 110.982 163.583 1.00 92.46  ?  243 THR B OG1 1 
ATOM   4266 C CG2 . THR B 2 240 ? 122.010 112.006 164.654 1.00 77.25  ?  243 THR B CG2 1 
ATOM   4267 N N   . GLY B 2 241 ? 121.500 113.181 160.380 1.00 78.90  ?  244 GLY B N   1 
ATOM   4268 C CA  . GLY B 2 241 ? 121.355 112.878 158.973 1.00 80.87  ?  244 GLY B CA  1 
ATOM   4269 C C   . GLY B 2 241 ? 122.433 111.920 158.521 1.00 79.72  ?  244 GLY B C   1 
ATOM   4270 O O   . GLY B 2 241 ? 123.620 112.194 158.706 1.00 83.07  ?  244 GLY B O   1 
ATOM   4271 N N   . SER B 2 242 ? 122.048 110.798 157.932 1.00 87.46  ?  245 SER B N   1 
ATOM   4272 C CA  . SER B 2 242 ? 122.998 109.746 157.618 1.00 85.01  ?  245 SER B CA  1 
ATOM   4273 C C   . SER B 2 242 ? 122.942 109.397 156.136 1.00 84.66  ?  245 SER B C   1 
ATOM   4274 O O   . SER B 2 242 ? 122.184 109.978 155.360 1.00 95.06  ?  245 SER B O   1 
ATOM   4275 C CB  . SER B 2 242 ? 122.733 108.508 158.472 1.00 89.71  ?  245 SER B CB  1 
ATOM   4276 O OG  . SER B 2 242 ? 121.995 107.555 157.744 1.00 92.39  ?  245 SER B OG  1 
ATOM   4277 N N   . ASP B 2 243 ? 123.767 108.422 155.755 1.00 91.98  ?  246 ASP B N   1 
ATOM   4278 C CA  . ASP B 2 243 ? 123.906 108.009 154.366 1.00 91.99  ?  246 ASP B CA  1 
ATOM   4279 C C   . ASP B 2 243 ? 122.778 107.108 153.887 1.00 94.64  ?  246 ASP B C   1 
ATOM   4280 O O   . ASP B 2 243 ? 122.684 106.856 152.683 1.00 92.94  ?  246 ASP B O   1 
ATOM   4281 C CB  . ASP B 2 243 ? 125.239 107.289 154.168 1.00 92.19  ?  246 ASP B CB  1 
ATOM   4282 C CG  . ASP B 2 243 ? 126.303 108.190 153.589 1.00 105.51 ?  246 ASP B CG  1 
ATOM   4283 O OD1 . ASP B 2 243 ? 125.969 109.316 153.172 1.00 103.91 ?  246 ASP B OD1 1 
ATOM   4284 O OD2 . ASP B 2 243 ? 127.478 107.771 153.550 1.00 109.24 -1 246 ASP B OD2 1 
ATOM   4285 N N   . ASP B 2 244 ? 121.927 106.614 154.785 1.00 91.00  ?  247 ASP B N   1 
ATOM   4286 C CA  . ASP B 2 244 ? 120.829 105.739 154.407 1.00 88.75  ?  247 ASP B CA  1 
ATOM   4287 C C   . ASP B 2 244 ? 119.572 106.509 154.028 1.00 95.00  ?  247 ASP B C   1 
ATOM   4288 O O   . ASP B 2 244 ? 118.469 105.961 154.126 1.00 96.89  ?  247 ASP B O   1 
ATOM   4289 C CB  . ASP B 2 244 ? 120.527 104.749 155.532 1.00 93.93  ?  247 ASP B CB  1 
ATOM   4290 C CG  . ASP B 2 244 ? 120.091 105.429 156.805 1.00 100.55 ?  247 ASP B CG  1 
ATOM   4291 O OD1 . ASP B 2 244 ? 120.328 106.641 156.937 1.00 104.40 ?  247 ASP B OD1 1 
ATOM   4292 O OD2 . ASP B 2 244 ? 119.515 104.753 157.680 1.00 102.02 -1 247 ASP B OD2 1 
ATOM   4293 N N   . ALA B 2 245 ? 119.719 107.767 153.610 1.00 92.62  ?  248 ALA B N   1 
ATOM   4294 C CA  . ALA B 2 245 ? 118.620 108.566 153.071 1.00 92.73  ?  248 ALA B CA  1 
ATOM   4295 C C   . ALA B 2 245 ? 117.510 108.775 154.093 1.00 99.82  ?  248 ALA B C   1 
ATOM   4296 O O   . ALA B 2 245 ? 116.324 108.746 153.760 1.00 105.21 ?  248 ALA B O   1 
ATOM   4297 C CB  . ALA B 2 245 ? 118.060 107.942 151.792 1.00 99.74  ?  248 ALA B CB  1 
ATOM   4298 N N   . THR B 2 246 ? 117.889 108.994 155.346 1.00 91.56  ?  249 THR B N   1 
ATOM   4299 C CA  . THR B 2 246 ? 116.907 109.235 156.386 1.00 87.16  ?  249 THR B CA  1 
ATOM   4300 C C   . THR B 2 246 ? 117.473 110.199 157.418 1.00 87.97  ?  249 THR B C   1 
ATOM   4301 O O   . THR B 2 246 ? 118.687 110.293 157.610 1.00 92.20  ?  249 THR B O   1 
ATOM   4302 C CB  . THR B 2 246 ? 116.468 107.923 157.051 1.00 83.99  ?  249 THR B CB  1 
ATOM   4303 O OG1 . THR B 2 246 ? 115.202 108.112 157.685 1.00 89.77  ?  249 THR B OG1 1 
ATOM   4304 C CG2 . THR B 2 246 ? 117.470 107.479 158.089 1.00 85.89  ?  249 THR B CG2 1 
ATOM   4305 N N   . CYS B 2 247 ? 116.571 110.935 158.058 1.00 85.79  ?  250 CYS B N   1 
ATOM   4306 C CA  . CYS B 2 247 ? 116.884 111.795 159.188 1.00 74.96  ?  250 CYS B CA  1 
ATOM   4307 C C   . CYS B 2 247 ? 116.063 111.326 160.375 1.00 80.89  ?  250 CYS B C   1 
ATOM   4308 O O   . CYS B 2 247 ? 114.874 111.033 160.236 1.00 96.86  ?  250 CYS B O   1 
ATOM   4309 C CB  . CYS B 2 247 ? 116.572 113.264 158.889 1.00 74.89  ?  250 CYS B CB  1 
ATOM   4310 S SG  . CYS B 2 247 ? 117.696 114.075 157.740 1.00 99.33  ?  250 CYS B SG  1 
ATOM   4311 N N   . ARG B 2 248 ? 116.694 111.239 161.538 1.00 73.91  ?  251 ARG B N   1 
ATOM   4312 C CA  . ARG B 2 248 ? 116.027 110.754 162.734 1.00 77.63  ?  251 ARG B CA  1 
ATOM   4313 C C   . ARG B 2 248 ? 116.160 111.776 163.849 1.00 79.89  ?  251 ARG B C   1 
ATOM   4314 O O   . ARG B 2 248 ? 117.211 112.399 164.009 1.00 88.21  ?  251 ARG B O   1 
ATOM   4315 C CB  . ARG B 2 248 ? 116.604 109.414 163.180 1.00 86.85  ?  251 ARG B CB  1 
ATOM   4316 C CG  . ARG B 2 248 ? 116.989 108.525 162.025 1.00 95.25  ?  251 ARG B CG  1 
ATOM   4317 C CD  . ARG B 2 248 ? 116.980 107.067 162.396 1.00 85.36  ?  251 ARG B CD  1 
ATOM   4318 N NE  . ARG B 2 248 ? 117.274 106.218 161.251 1.00 88.64  ?  251 ARG B NE  1 
ATOM   4319 C CZ  . ARG B 2 248 ? 116.581 105.138 160.923 1.00 95.42  ?  251 ARG B CZ  1 
ATOM   4320 N NH1 . ARG B 2 248 ? 115.542 104.743 161.638 1.00 90.04  1  251 ARG B NH1 1 
ATOM   4321 N NH2 . ARG B 2 248 ? 116.939 104.439 159.851 1.00 94.74  ?  251 ARG B NH2 1 
ATOM   4322 N N   . LEU B 2 249 ? 115.089 111.945 164.613 1.00 66.93  ?  252 LEU B N   1 
ATOM   4323 C CA  . LEU B 2 249 ? 115.080 112.823 165.773 1.00 71.55  ?  252 LEU B CA  1 
ATOM   4324 C C   . LEU B 2 249 ? 115.194 111.973 167.029 1.00 74.63  ?  252 LEU B C   1 
ATOM   4325 O O   . LEU B 2 249 ? 114.332 111.131 167.293 1.00 86.71  ?  252 LEU B O   1 
ATOM   4326 C CB  . LEU B 2 249 ? 113.811 113.674 165.803 1.00 73.12  ?  252 LEU B CB  1 
ATOM   4327 C CG  . LEU B 2 249 ? 113.824 114.894 166.720 1.00 67.43  ?  252 LEU B CG  1 
ATOM   4328 C CD1 . LEU B 2 249 ? 113.240 116.086 166.014 1.00 69.16  ?  252 LEU B CD1 1 
ATOM   4329 C CD2 . LEU B 2 249 ? 113.029 114.602 167.963 1.00 73.36  ?  252 LEU B CD2 1 
ATOM   4330 N N   . PHE B 2 250 ? 116.259 112.188 167.792 1.00 71.93  ?  253 PHE B N   1 
ATOM   4331 C CA  . PHE B 2 250 ? 116.486 111.478 169.038 1.00 69.33  ?  253 PHE B CA  1 
ATOM   4332 C C   . PHE B 2 250 ? 116.184 112.390 170.215 1.00 72.27  ?  253 PHE B C   1 
ATOM   4333 O O   . PHE B 2 250 ? 116.189 113.616 170.098 1.00 86.09  ?  253 PHE B O   1 
ATOM   4334 C CB  . PHE B 2 250 ? 117.924 110.964 169.131 1.00 75.58  ?  253 PHE B CB  1 
ATOM   4335 C CG  . PHE B 2 250 ? 118.251 109.908 168.126 1.00 75.73  ?  253 PHE B CG  1 
ATOM   4336 C CD1 . PHE B 2 250 ? 117.983 108.582 168.391 1.00 70.73  ?  253 PHE B CD1 1 
ATOM   4337 C CD2 . PHE B 2 250 ? 118.828 110.239 166.918 1.00 74.33  ?  253 PHE B CD2 1 
ATOM   4338 C CE1 . PHE B 2 250 ? 118.281 107.611 167.472 1.00 79.06  ?  253 PHE B CE1 1 
ATOM   4339 C CE2 . PHE B 2 250 ? 119.128 109.270 165.997 1.00 68.39  ?  253 PHE B CE2 1 
ATOM   4340 C CZ  . PHE B 2 250 ? 118.854 107.955 166.274 1.00 75.34  ?  253 PHE B CZ  1 
ATOM   4341 N N   . ASP B 2 251 ? 115.928 111.772 171.360 1.00 103.65 ?  254 ASP B N   1 
ATOM   4342 C CA  . ASP B 2 251 ? 115.480 112.478 172.551 1.00 105.58 ?  254 ASP B CA  1 
ATOM   4343 C C   . ASP B 2 251 ? 116.423 112.156 173.700 1.00 104.05 ?  254 ASP B C   1 
ATOM   4344 O O   . ASP B 2 251 ? 116.631 110.983 174.022 1.00 106.02 ?  254 ASP B O   1 
ATOM   4345 C CB  . ASP B 2 251 ? 114.048 112.079 172.889 1.00 104.31 ?  254 ASP B CB  1 
ATOM   4346 C CG  . ASP B 2 251 ? 113.380 113.050 173.820 1.00 114.86 ?  254 ASP B CG  1 
ATOM   4347 O OD1 . ASP B 2 251 ? 113.996 114.074 174.175 1.00 115.30 ?  254 ASP B OD1 1 
ATOM   4348 O OD2 . ASP B 2 251 ? 112.222 112.789 174.185 1.00 121.33 -1 254 ASP B OD2 1 
ATOM   4349 N N   . LEU B 2 252 ? 116.985 113.195 174.319 1.00 94.52  ?  255 LEU B N   1 
ATOM   4350 C CA  . LEU B 2 252 ? 117.974 112.984 175.371 1.00 91.42  ?  255 LEU B CA  1 
ATOM   4351 C C   . LEU B 2 252 ? 117.343 112.368 176.612 1.00 94.43  ?  255 LEU B C   1 
ATOM   4352 O O   . LEU B 2 252 ? 117.860 111.393 177.167 1.00 103.46 ?  255 LEU B O   1 
ATOM   4353 C CB  . LEU B 2 252 ? 118.657 114.304 175.723 1.00 92.56  ?  255 LEU B CB  1 
ATOM   4354 C CG  . LEU B 2 252 ? 120.002 114.606 175.066 1.00 96.91  ?  255 LEU B CG  1 
ATOM   4355 C CD1 . LEU B 2 252 ? 119.933 114.388 173.575 1.00 99.45  ?  255 LEU B CD1 1 
ATOM   4356 C CD2 . LEU B 2 252 ? 120.436 116.023 175.377 1.00 98.68  ?  255 LEU B CD2 1 
ATOM   4357 N N   . ARG B 2 253 ? 116.226 112.933 177.069 1.00 113.47 ?  256 ARG B N   1 
ATOM   4358 C CA  . ARG B 2 253 ? 115.621 112.471 178.313 1.00 117.06 ?  256 ARG B CA  1 
ATOM   4359 C C   . ARG B 2 253 ? 115.005 111.088 178.148 1.00 120.61 ?  256 ARG B C   1 
ATOM   4360 O O   . ARG B 2 253 ? 115.171 110.217 179.009 1.00 118.79 ?  256 ARG B O   1 
ATOM   4361 C CB  . ARG B 2 253 ? 114.575 113.478 178.788 1.00 119.31 ?  256 ARG B CB  1 
ATOM   4362 C CG  . ARG B 2 253 ? 115.140 114.577 179.666 1.00 120.96 ?  256 ARG B CG  1 
ATOM   4363 C CD  . ARG B 2 253 ? 114.116 115.669 179.889 1.00 117.30 ?  256 ARG B CD  1 
ATOM   4364 N NE  . ARG B 2 253 ? 113.419 116.010 178.656 1.00 117.52 ?  256 ARG B NE  1 
ATOM   4365 C CZ  . ARG B 2 253 ? 112.278 116.681 178.604 1.00 123.52 ?  256 ARG B CZ  1 
ATOM   4366 N NH1 . ARG B 2 253 ? 111.669 117.093 179.703 1.00 120.38 1  256 ARG B NH1 1 
ATOM   4367 N NH2 . ARG B 2 253 ? 111.733 116.942 177.420 1.00 125.05 ?  256 ARG B NH2 1 
ATOM   4368 N N   . ALA B 2 254 ? 114.288 110.866 177.047 1.00 115.90 ?  257 ALA B N   1 
ATOM   4369 C CA  . ALA B 2 254 ? 113.702 109.560 176.788 1.00 111.95 ?  257 ALA B CA  1 
ATOM   4370 C C   . ALA B 2 254 ? 114.723 108.549 176.289 1.00 110.79 ?  257 ALA B C   1 
ATOM   4371 O O   . ALA B 2 254 ? 114.441 107.347 176.311 1.00 112.39 ?  257 ALA B O   1 
ATOM   4372 C CB  . ALA B 2 254 ? 112.561 109.684 175.776 1.00 106.21 ?  257 ALA B CB  1 
ATOM   4373 N N   . ASP B 2 255 ? 115.896 109.009 175.847 1.00 111.58 ?  258 ASP B N   1 
ATOM   4374 C CA  . ASP B 2 255 ? 116.975 108.135 175.387 1.00 111.87 ?  258 ASP B CA  1 
ATOM   4375 C C   . ASP B 2 255 ? 116.504 107.217 174.262 1.00 109.12 ?  258 ASP B C   1 
ATOM   4376 O O   . ASP B 2 255 ? 116.791 106.020 174.243 1.00 117.73 ?  258 ASP B O   1 
ATOM   4377 C CB  . ASP B 2 255 ? 117.554 107.328 176.551 1.00 111.72 ?  258 ASP B CB  1 
ATOM   4378 C CG  . ASP B 2 255 ? 118.983 106.908 176.313 1.00 118.75 ?  258 ASP B CG  1 
ATOM   4379 O OD1 . ASP B 2 255 ? 119.803 107.779 175.963 1.00 119.25 ?  258 ASP B OD1 1 
ATOM   4380 O OD2 . ASP B 2 255 ? 119.291 105.710 176.485 1.00 118.85 -1 258 ASP B OD2 1 
ATOM   4381 N N   . GLN B 2 256 ? 115.778 107.792 173.309 1.00 103.03 ?  259 GLN B N   1 
ATOM   4382 C CA  . GLN B 2 256 ? 115.131 106.991 172.285 1.00 103.24 ?  259 GLN B CA  1 
ATOM   4383 C C   . GLN B 2 256 ? 115.023 107.780 170.993 1.00 108.57 ?  259 GLN B C   1 
ATOM   4384 O O   . GLN B 2 256 ? 115.089 109.011 170.980 1.00 115.07 ?  259 GLN B O   1 
ATOM   4385 C CB  . GLN B 2 256 ? 113.733 106.552 172.719 1.00 102.96 ?  259 GLN B CB  1 
ATOM   4386 C CG  . GLN B 2 256 ? 113.686 105.236 173.438 1.00 107.23 ?  259 GLN B CG  1 
ATOM   4387 C CD  . GLN B 2 256 ? 112.373 105.030 174.143 1.00 114.06 ?  259 GLN B CD  1 
ATOM   4388 O OE1 . GLN B 2 256 ? 111.399 104.592 173.538 1.00 115.63 ?  259 GLN B OE1 1 
ATOM   4389 N NE2 . GLN B 2 256 ? 112.332 105.351 175.429 1.00 117.23 ?  259 GLN B NE2 1 
ATOM   4390 N N   . GLU B 2 257 ? 114.849 107.044 169.904 1.00 105.90 ?  260 GLU B N   1 
ATOM   4391 C CA  . GLU B 2 257 ? 114.438 107.643 168.646 1.00 100.35 ?  260 GLU B CA  1 
ATOM   4392 C C   . GLU B 2 257 ? 113.009 108.144 168.777 1.00 105.63 ?  260 GLU B C   1 
ATOM   4393 O O   . GLU B 2 257 ? 112.151 107.452 169.330 1.00 111.74 ?  260 GLU B O   1 
ATOM   4394 C CB  . GLU B 2 257 ? 114.524 106.614 167.528 1.00 100.35 ?  260 GLU B CB  1 
ATOM   4395 C CG  . GLU B 2 257 ? 114.316 107.166 166.145 1.00 106.51 ?  260 GLU B CG  1 
ATOM   4396 C CD  . GLU B 2 257 ? 114.187 106.064 165.124 1.00 114.86 ?  260 GLU B CD  1 
ATOM   4397 O OE1 . GLU B 2 257 ? 115.144 105.837 164.365 1.00 108.85 ?  260 GLU B OE1 1 
ATOM   4398 O OE2 . GLU B 2 257 ? 113.115 105.426 165.074 1.00 117.84 -1 260 GLU B OE2 1 
ATOM   4399 N N   . LEU B 2 258 ? 112.747 109.344 168.269 1.00 92.76  ?  261 LEU B N   1 
ATOM   4400 C CA  . LEU B 2 258 ? 111.399 109.896 168.298 1.00 88.51  ?  261 LEU B CA  1 
ATOM   4401 C C   . LEU B 2 258 ? 110.703 109.793 166.949 1.00 94.11  ?  261 LEU B C   1 
ATOM   4402 O O   . LEU B 2 258 ? 109.568 109.319 166.870 1.00 100.76 ?  261 LEU B O   1 
ATOM   4403 C CB  . LEU B 2 258 ? 111.437 111.358 168.753 1.00 94.66  ?  261 LEU B CB  1 
ATOM   4404 C CG  . LEU B 2 258 ? 111.378 111.588 170.260 1.00 95.69  ?  261 LEU B CG  1 
ATOM   4405 C CD1 . LEU B 2 258 ? 111.063 113.034 170.570 1.00 99.22  ?  261 LEU B CD1 1 
ATOM   4406 C CD2 . LEU B 2 258 ? 110.352 110.678 170.881 1.00 96.05  ?  261 LEU B CD2 1 
ATOM   4407 N N   . MET B 2 259 ? 111.376 110.210 165.882 1.00 100.02 ?  262 MET B N   1 
ATOM   4408 C CA  . MET B 2 259 ? 110.775 110.276 164.561 1.00 99.44  ?  262 MET B CA  1 
ATOM   4409 C C   . MET B 2 259 ? 111.833 110.028 163.501 1.00 100.69 ?  262 MET B C   1 
ATOM   4410 O O   . MET B 2 259 ? 113.024 110.263 163.711 1.00 104.65 ?  262 MET B O   1 
ATOM   4411 C CB  . MET B 2 259 ? 110.084 111.625 164.338 1.00 97.96  ?  262 MET B CB  1 
ATOM   4412 C CG  . MET B 2 259 ? 109.115 111.647 163.180 1.00 101.65 ?  262 MET B CG  1 
ATOM   4413 S SD  . MET B 2 259 ? 107.519 112.398 163.513 1.00 121.92 ?  262 MET B SD  1 
ATOM   4414 C CE  . MET B 2 259 ? 106.689 111.012 164.263 1.00 108.63 ?  262 MET B CE  1 
ATOM   4415 N N   . THR B 2 260 ? 111.373 109.540 162.354 1.00 93.39  ?  263 THR B N   1 
ATOM   4416 C CA  . THR B 2 260 ? 112.215 109.277 161.198 1.00 93.89  ?  263 THR B CA  1 
ATOM   4417 C C   . THR B 2 260 ? 111.705 110.104 160.029 1.00 90.74  ?  263 THR B C   1 
ATOM   4418 O O   . THR B 2 260 ? 110.512 110.068 159.713 1.00 95.40  ?  263 THR B O   1 
ATOM   4419 C CB  . THR B 2 260 ? 112.205 107.793 160.841 1.00 96.98  ?  263 THR B CB  1 
ATOM   4420 O OG1 . THR B 2 260 ? 112.089 107.017 162.037 1.00 100.73 ?  263 THR B OG1 1 
ATOM   4421 C CG2 . THR B 2 260 ? 113.484 107.418 160.143 1.00 91.97  ?  263 THR B CG2 1 
ATOM   4422 N N   . TYR B 2 261 ? 112.603 110.845 159.395 1.00 77.54  ?  264 TYR B N   1 
ATOM   4423 C CA  . TYR B 2 261 ? 112.262 111.727 158.284 1.00 81.10  ?  264 TYR B CA  1 
ATOM   4424 C C   . TYR B 2 261 ? 112.785 111.078 157.007 1.00 88.47  ?  264 TYR B C   1 
ATOM   4425 O O   . TYR B 2 261 ? 113.912 111.325 156.580 1.00 83.63  ?  264 TYR B O   1 
ATOM   4426 C CB  . TYR B 2 261 ? 112.845 113.115 158.501 1.00 86.14  ?  264 TYR B CB  1 
ATOM   4427 C CG  . TYR B 2 261 ? 112.447 113.718 159.825 1.00 84.17  ?  264 TYR B CG  1 
ATOM   4428 C CD1 . TYR B 2 261 ? 111.224 114.344 159.981 1.00 88.76  ?  264 TYR B CD1 1 
ATOM   4429 C CD2 . TYR B 2 261 ? 113.291 113.654 160.919 1.00 84.16  ?  264 TYR B CD2 1 
ATOM   4430 C CE1 . TYR B 2 261 ? 110.857 114.887 161.186 1.00 88.26  ?  264 TYR B CE1 1 
ATOM   4431 C CE2 . TYR B 2 261 ? 112.930 114.196 162.127 1.00 80.66  ?  264 TYR B CE2 1 
ATOM   4432 C CZ  . TYR B 2 261 ? 111.713 114.810 162.255 1.00 82.30  ?  264 TYR B CZ  1 
ATOM   4433 O OH  . TYR B 2 261 ? 111.348 115.354 163.460 1.00 91.61  ?  264 TYR B OH  1 
ATOM   4434 N N   . SER B 2 262 ? 111.948 110.242 156.398 1.00 104.67 ?  265 SER B N   1 
ATOM   4435 C CA  . SER B 2 262 ? 112.336 109.471 155.230 1.00 101.83 ?  265 SER B CA  1 
ATOM   4436 C C   . SER B 2 262 ? 111.232 109.533 154.190 1.00 101.41 ?  265 SER B C   1 
ATOM   4437 O O   . SER B 2 262 ? 110.061 109.754 154.506 1.00 106.65 ?  265 SER B O   1 
ATOM   4438 C CB  . SER B 2 262 ? 112.623 108.011 155.591 1.00 104.73 ?  265 SER B CB  1 
ATOM   4439 O OG  . SER B 2 262 ? 111.463 107.388 156.114 1.00 102.97 ?  265 SER B OG  1 
ATOM   4440 N N   . HIS B 2 263 ? 111.623 109.331 152.936 1.00 113.10 ?  266 HIS B N   1 
ATOM   4441 C CA  . HIS B 2 263 ? 110.679 109.269 151.833 1.00 116.64 ?  266 HIS B CA  1 
ATOM   4442 C C   . HIS B 2 263 ? 111.218 108.299 150.794 1.00 120.42 ?  266 HIS B C   1 
ATOM   4443 O O   . HIS B 2 263 ? 112.431 108.130 150.655 1.00 124.80 ?  266 HIS B O   1 
ATOM   4444 C CB  . HIS B 2 263 ? 110.446 110.653 151.221 1.00 114.80 ?  266 HIS B CB  1 
ATOM   4445 C CG  . HIS B 2 263 ? 109.127 110.798 150.531 1.00 118.97 ?  266 HIS B CG  1 
ATOM   4446 N ND1 . HIS B 2 263 ? 108.209 109.774 150.454 1.00 118.43 ?  266 HIS B ND1 1 
ATOM   4447 C CD2 . HIS B 2 263 ? 108.565 111.855 149.899 1.00 114.33 ?  266 HIS B CD2 1 
ATOM   4448 C CE1 . HIS B 2 263 ? 107.143 110.190 149.795 1.00 118.39 ?  266 HIS B CE1 1 
ATOM   4449 N NE2 . HIS B 2 263 ? 107.334 111.449 149.447 1.00 116.42 ?  266 HIS B NE2 1 
ATOM   4450 N N   . ASP B 2 264 ? 110.301 107.660 150.066 1.00 118.05 ?  267 ASP B N   1 
ATOM   4451 C CA  . ASP B 2 264 ? 110.700 106.642 149.099 1.00 115.95 ?  267 ASP B CA  1 
ATOM   4452 C C   . ASP B 2 264 ? 111.478 107.235 147.932 1.00 116.54 ?  267 ASP B C   1 
ATOM   4453 O O   . ASP B 2 264 ? 112.394 106.590 147.411 1.00 116.24 ?  267 ASP B O   1 
ATOM   4454 C CB  . ASP B 2 264 ? 109.471 105.894 148.591 1.00 115.97 ?  267 ASP B CB  1 
ATOM   4455 C CG  . ASP B 2 264 ? 109.011 104.817 149.549 1.00 122.77 ?  267 ASP B CG  1 
ATOM   4456 O OD1 . ASP B 2 264 ? 109.738 103.816 149.709 1.00 122.56 ?  267 ASP B OD1 1 
ATOM   4457 O OD2 . ASP B 2 264 ? 107.925 104.969 150.145 1.00 124.71 -1 267 ASP B OD2 1 
ATOM   4458 N N   . ASN B 2 265 ? 111.124 108.446 147.500 1.00 118.32 ?  268 ASN B N   1 
ATOM   4459 C CA  . ASN B 2 265 ? 111.824 109.062 146.377 1.00 118.69 ?  268 ASN B CA  1 
ATOM   4460 C C   . ASN B 2 265 ? 113.272 109.383 146.728 1.00 118.52 ?  268 ASN B C   1 
ATOM   4461 O O   . ASN B 2 265 ? 114.158 109.286 145.872 1.00 118.08 ?  268 ASN B O   1 
ATOM   4462 C CB  . ASN B 2 265 ? 111.090 110.324 145.931 1.00 117.99 ?  268 ASN B CB  1 
ATOM   4463 C CG  . ASN B 2 265 ? 109.605 110.253 146.194 1.00 123.06 ?  268 ASN B CG  1 
ATOM   4464 O OD1 . ASN B 2 265 ? 109.132 110.677 147.245 1.00 123.77 ?  268 ASN B OD1 1 
ATOM   4465 N ND2 . ASN B 2 265 ? 108.857 109.714 145.239 1.00 120.49 ?  268 ASN B ND2 1 
ATOM   4466 N N   . ILE B 2 266 ? 113.533 109.777 147.970 1.00 111.93 ?  269 ILE B N   1 
ATOM   4467 C CA  . ILE B 2 266 ? 114.883 110.144 148.386 1.00 110.64 ?  269 ILE B CA  1 
ATOM   4468 C C   . ILE B 2 266 ? 115.674 108.882 148.698 1.00 111.50 ?  269 ILE B C   1 
ATOM   4469 O O   . ILE B 2 266 ? 115.260 108.064 149.525 1.00 105.79 ?  269 ILE B O   1 
ATOM   4470 C CB  . ILE B 2 266 ? 114.854 111.089 149.593 1.00 107.46 ?  269 ILE B CB  1 
ATOM   4471 C CG1 . ILE B 2 266 ? 113.896 112.251 149.334 1.00 111.15 ?  269 ILE B CG1 1 
ATOM   4472 C CG2 . ILE B 2 266 ? 116.238 111.607 149.870 1.00 108.05 ?  269 ILE B CG2 1 
ATOM   4473 C CD1 . ILE B 2 266 ? 113.207 112.757 150.566 1.00 105.95 ?  269 ILE B CD1 1 
ATOM   4474 N N   . ILE B 2 267 ? 116.818 108.726 148.037 1.00 112.93 ?  270 ILE B N   1 
ATOM   4475 C CA  . ILE B 2 267 ? 117.649 107.539 148.186 1.00 111.45 ?  270 ILE B CA  1 
ATOM   4476 C C   . ILE B 2 267 ? 119.107 107.932 148.386 1.00 113.15 ?  270 ILE B C   1 
ATOM   4477 O O   . ILE B 2 267 ? 119.994 107.073 148.379 1.00 111.62 ?  270 ILE B O   1 
ATOM   4478 C CB  . ILE B 2 267 ? 117.487 106.608 146.973 1.00 111.43 ?  270 ILE B CB  1 
ATOM   4479 C CG1 . ILE B 2 267 ? 117.418 107.433 145.689 1.00 111.60 ?  270 ILE B CG1 1 
ATOM   4480 C CG2 . ILE B 2 267 ? 116.245 105.756 147.124 1.00 107.56 ?  270 ILE B CG2 1 
ATOM   4481 C CD1 . ILE B 2 267 ? 117.104 106.628 144.459 1.00 112.52 ?  270 ILE B CD1 1 
ATOM   4482 N N   . CYS B 2 268 ? 119.368 109.221 148.562 1.00 109.40 ?  271 CYS B N   1 
ATOM   4483 C CA  . CYS B 2 268 ? 120.722 109.731 148.727 1.00 107.12 ?  271 CYS B CA  1 
ATOM   4484 C C   . CYS B 2 268 ? 120.999 110.031 150.192 1.00 108.70 ?  271 CYS B C   1 
ATOM   4485 O O   . CYS B 2 268 ? 120.085 110.226 150.993 1.00 109.13 ?  271 CYS B O   1 
ATOM   4486 C CB  . CYS B 2 268 ? 120.923 111.012 147.927 1.00 102.16 ?  271 CYS B CB  1 
ATOM   4487 S SG  . CYS B 2 268 ? 119.851 112.310 148.528 1.00 117.65 ?  271 CYS B SG  1 
ATOM   4488 N N   . GLY B 2 269 ? 122.277 110.108 150.527 1.00 88.03  ?  272 GLY B N   1 
ATOM   4489 C CA  . GLY B 2 269 ? 122.659 110.476 151.870 1.00 89.61  ?  272 GLY B CA  1 
ATOM   4490 C C   . GLY B 2 269 ? 122.386 111.937 152.172 1.00 85.68  ?  272 GLY B C   1 
ATOM   4491 O O   . GLY B 2 269 ? 122.156 112.765 151.293 1.00 95.09  ?  272 GLY B O   1 
ATOM   4492 N N   . ILE B 2 270 ? 122.414 112.250 153.462 1.00 74.05  ?  273 ILE B N   1 
ATOM   4493 C CA  . ILE B 2 270 ? 122.224 113.606 153.957 1.00 70.79  ?  273 ILE B CA  1 
ATOM   4494 C C   . ILE B 2 270 ? 123.584 114.161 154.343 1.00 76.12  ?  273 ILE B C   1 
ATOM   4495 O O   . ILE B 2 270 ? 124.352 113.501 155.051 1.00 84.82  ?  273 ILE B O   1 
ATOM   4496 C CB  . ILE B 2 270 ? 121.260 113.635 155.153 1.00 66.46  ?  273 ILE B CB  1 
ATOM   4497 C CG1 . ILE B 2 270 ? 119.846 113.297 154.703 1.00 65.40  ?  273 ILE B CG1 1 
ATOM   4498 C CG2 . ILE B 2 270 ? 121.270 114.991 155.808 1.00 70.24  ?  273 ILE B CG2 1 
ATOM   4499 C CD1 . ILE B 2 270 ? 119.490 111.858 154.875 1.00 79.38  ?  273 ILE B CD1 1 
ATOM   4500 N N   . THR B 2 271 ? 123.891 115.366 153.874 1.00 68.44  ?  274 THR B N   1 
ATOM   4501 C CA  . THR B 2 271 ? 125.176 115.983 154.164 1.00 66.43  ?  274 THR B CA  1 
ATOM   4502 C C   . THR B 2 271 ? 125.124 116.979 155.312 1.00 74.63  ?  274 THR B C   1 
ATOM   4503 O O   . THR B 2 271 ? 126.155 117.219 155.945 1.00 81.51  ?  274 THR B O   1 
ATOM   4504 C CB  . THR B 2 271 ? 125.716 116.688 152.919 1.00 73.19  ?  274 THR B CB  1 
ATOM   4505 O OG1 . THR B 2 271 ? 124.672 117.462 152.323 1.00 83.41  ?  274 THR B OG1 1 
ATOM   4506 C CG2 . THR B 2 271 ? 126.205 115.675 151.910 1.00 70.56  ?  274 THR B CG2 1 
ATOM   4507 N N   . SER B 2 272 ? 123.961 117.558 155.596 1.00 74.54  ?  275 SER B N   1 
ATOM   4508 C CA  . SER B 2 272 ? 123.852 118.585 156.620 1.00 67.59  ?  275 SER B CA  1 
ATOM   4509 C C   . SER B 2 272 ? 122.408 118.680 157.078 1.00 68.20  ?  275 SER B C   1 
ATOM   4510 O O   . SER B 2 272 ? 121.491 118.538 156.271 1.00 86.53  ?  275 SER B O   1 
ATOM   4511 C CB  . SER B 2 272 ? 124.329 119.937 156.091 1.00 77.71  ?  275 SER B CB  1 
ATOM   4512 O OG  . SER B 2 272 ? 123.812 120.172 154.795 1.00 86.34  ?  275 SER B OG  1 
ATOM   4513 N N   . VAL B 2 273 ? 122.214 118.915 158.376 1.00 65.19  ?  276 VAL B N   1 
ATOM   4514 C CA  . VAL B 2 273 ? 120.896 119.153 158.946 1.00 70.17  ?  276 VAL B CA  1 
ATOM   4515 C C   . VAL B 2 273 ? 120.962 120.398 159.817 1.00 74.22  ?  276 VAL B C   1 
ATOM   4516 O O   . VAL B 2 273 ? 122.019 120.777 160.322 1.00 87.05  ?  276 VAL B O   1 
ATOM   4517 C CB  . VAL B 2 273 ? 120.370 117.959 159.771 1.00 52.28  ?  276 VAL B CB  1 
ATOM   4518 C CG1 . VAL B 2 273 ? 120.094 116.772 158.881 1.00 66.37  ?  276 VAL B CG1 1 
ATOM   4519 C CG2 . VAL B 2 273 ? 121.354 117.595 160.852 1.00 71.28  ?  276 VAL B CG2 1 
ATOM   4520 N N   . SER B 2 274 ? 119.807 121.037 159.983 1.00 66.08  ?  277 SER B N   1 
ATOM   4521 C CA  . SER B 2 274 ? 119.676 122.178 160.875 1.00 60.88  ?  277 SER B CA  1 
ATOM   4522 C C   . SER B 2 274 ? 118.204 122.381 161.185 1.00 66.63  ?  277 SER B C   1 
ATOM   4523 O O   . SER B 2 274 ? 117.336 122.010 160.395 1.00 80.31  ?  277 SER B O   1 
ATOM   4524 C CB  . SER B 2 274 ? 120.267 123.451 160.267 1.00 73.23  ?  277 SER B CB  1 
ATOM   4525 O OG  . SER B 2 274 ? 120.867 124.265 161.258 1.00 84.81  ?  277 SER B OG  1 
ATOM   4526 N N   . PHE B 2 275 ? 117.938 122.974 162.339 1.00 61.72  ?  278 PHE B N   1 
ATOM   4527 C CA  . PHE B 2 275 ? 116.586 123.287 162.769 1.00 67.33  ?  278 PHE B CA  1 
ATOM   4528 C C   . PHE B 2 275 ? 116.289 124.761 162.533 1.00 77.62  ?  278 PHE B C   1 
ATOM   4529 O O   . PHE B 2 275 ? 117.193 125.585 162.384 1.00 92.13  ?  278 PHE B O   1 
ATOM   4530 C CB  . PHE B 2 275 ? 116.398 122.956 164.249 1.00 73.94  ?  278 PHE B CB  1 
ATOM   4531 C CG  . PHE B 2 275 ? 116.059 121.522 164.517 1.00 74.50  ?  278 PHE B CG  1 
ATOM   4532 C CD1 . PHE B 2 275 ? 114.765 121.066 164.373 1.00 72.99  ?  278 PHE B CD1 1 
ATOM   4533 C CD2 . PHE B 2 275 ? 117.031 120.635 164.929 1.00 74.17  ?  278 PHE B CD2 1 
ATOM   4534 C CE1 . PHE B 2 275 ? 114.452 119.753 164.628 1.00 73.64  ?  278 PHE B CE1 1 
ATOM   4535 C CE2 . PHE B 2 275 ? 116.722 119.324 165.183 1.00 72.22  ?  278 PHE B CE2 1 
ATOM   4536 C CZ  . PHE B 2 275 ? 115.433 118.881 165.034 1.00 72.76  ?  278 PHE B CZ  1 
ATOM   4537 N N   . SER B 2 276 ? 115.003 125.089 162.501 1.00 76.84  ?  279 SER B N   1 
ATOM   4538 C CA  . SER B 2 276 ? 114.599 126.481 162.437 1.00 74.90  ?  279 SER B CA  1 
ATOM   4539 C C   . SER B 2 276 ? 114.702 127.103 163.829 1.00 88.60  ?  279 SER B C   1 
ATOM   4540 O O   . SER B 2 276 ? 115.086 126.449 164.801 1.00 93.14  ?  279 SER B O   1 
ATOM   4541 C CB  . SER B 2 276 ? 113.190 126.601 161.865 1.00 82.28  ?  279 SER B CB  1 
ATOM   4542 O OG  . SER B 2 276 ? 112.233 126.738 162.896 1.00 95.37  ?  279 SER B OG  1 
ATOM   4543 N N   . LYS B 2 277 ? 114.360 128.388 163.930 1.00 99.02  ?  280 LYS B N   1 
ATOM   4544 C CA  . LYS B 2 277 ? 114.513 129.093 165.199 1.00 91.61  ?  280 LYS B CA  1 
ATOM   4545 C C   . LYS B 2 277 ? 113.653 128.468 166.289 1.00 91.13  ?  280 LYS B C   1 
ATOM   4546 O O   . LYS B 2 277 ? 114.097 128.322 167.433 1.00 91.42  ?  280 LYS B O   1 
ATOM   4547 C CB  . LYS B 2 277 ? 114.169 130.572 165.022 1.00 93.96  ?  280 LYS B CB  1 
ATOM   4548 C CG  . LYS B 2 277 ? 114.102 131.360 166.318 1.00 98.38  ?  280 LYS B CG  1 
ATOM   4549 C CD  . LYS B 2 277 ? 115.477 131.511 166.941 1.00 97.02  ?  280 LYS B CD  1 
ATOM   4550 C CE  . LYS B 2 277 ? 115.505 132.639 167.956 1.00 92.23  ?  280 LYS B CE  1 
ATOM   4551 N NZ  . LYS B 2 277 ? 115.522 133.970 167.303 1.00 94.87  1  280 LYS B NZ  1 
ATOM   4552 N N   . SER B 2 278 ? 112.420 128.095 165.958 1.00 82.31  ?  281 SER B N   1 
ATOM   4553 C CA  . SER B 2 278 ? 111.531 127.461 166.919 1.00 85.97  ?  281 SER B CA  1 
ATOM   4554 C C   . SER B 2 278 ? 111.690 125.950 166.976 1.00 90.03  ?  281 SER B C   1 
ATOM   4555 O O   . SER B 2 278 ? 111.141 125.322 167.884 1.00 90.76  ?  281 SER B O   1 
ATOM   4556 C CB  . SER B 2 278 ? 110.075 127.796 166.593 1.00 88.50  ?  281 SER B CB  1 
ATOM   4557 O OG  . SER B 2 278 ? 109.733 127.356 165.293 1.00 92.41  ?  281 SER B OG  1 
ATOM   4558 N N   . GLY B 2 279 ? 112.426 125.356 166.042 1.00 93.36  ?  282 GLY B N   1 
ATOM   4559 C CA  . GLY B 2 279 ? 112.555 123.919 165.976 1.00 88.89  ?  282 GLY B CA  1 
ATOM   4560 C C   . GLY B 2 279 ? 111.432 123.205 165.260 1.00 89.69  ?  282 GLY B C   1 
ATOM   4561 O O   . GLY B 2 279 ? 111.443 121.971 165.205 1.00 103.59 ?  282 GLY B O   1 
ATOM   4562 N N   . ARG B 2 280 ? 110.462 123.934 164.710 1.00 89.42  ?  283 ARG B N   1 
ATOM   4563 C CA  . ARG B 2 280 ? 109.356 123.293 164.011 1.00 86.54  ?  283 ARG B CA  1 
ATOM   4564 C C   . ARG B 2 280 ? 109.769 122.774 162.643 1.00 84.82  ?  283 ARG B C   1 
ATOM   4565 O O   . ARG B 2 280 ? 109.177 121.810 162.148 1.00 98.72  ?  283 ARG B O   1 
ATOM   4566 C CB  . ARG B 2 280 ? 108.189 124.269 163.871 1.00 86.71  ?  283 ARG B CB  1 
ATOM   4567 C CG  . ARG B 2 280 ? 106.956 123.677 163.227 1.00 80.06  ?  283 ARG B CG  1 
ATOM   4568 C CD  . ARG B 2 280 ? 106.404 122.534 164.043 1.00 86.09  ?  283 ARG B CD  1 
ATOM   4569 N NE  . ARG B 2 280 ? 105.352 121.825 163.328 1.00 92.15  ?  283 ARG B NE  1 
ATOM   4570 C CZ  . ARG B 2 280 ? 104.062 122.107 163.426 1.00 94.47  ?  283 ARG B CZ  1 
ATOM   4571 N NH1 . ARG B 2 280 ? 103.624 123.079 164.207 1.00 91.75  1  283 ARG B NH1 1 
ATOM   4572 N NH2 . ARG B 2 280 ? 103.188 121.398 162.720 1.00 97.35  ?  283 ARG B NH2 1 
ATOM   4573 N N   . LEU B 2 281 ? 110.770 123.383 162.021 1.00 73.21  ?  284 LEU B N   1 
ATOM   4574 C CA  . LEU B 2 281 ? 111.237 122.978 160.705 1.00 78.36  ?  284 LEU B CA  1 
ATOM   4575 C C   . LEU B 2 281 ? 112.608 122.335 160.831 1.00 80.73  ?  284 LEU B C   1 
ATOM   4576 O O   . LEU B 2 281 ? 113.477 122.854 161.536 1.00 95.83  ?  284 LEU B O   1 
ATOM   4577 C CB  . LEU B 2 281 ? 111.308 124.174 159.755 1.00 83.09  ?  284 LEU B CB  1 
ATOM   4578 C CG  . LEU B 2 281 ? 110.009 124.887 159.389 1.00 80.72  ?  284 LEU B CG  1 
ATOM   4579 C CD1 . LEU B 2 281 ? 110.293 125.941 158.344 1.00 81.74  ?  284 LEU B CD1 1 
ATOM   4580 C CD2 . LEU B 2 281 ? 108.970 123.906 158.892 1.00 79.59  ?  284 LEU B CD2 1 
ATOM   4581 N N   . LEU B 2 282 ? 112.796 121.209 160.156 1.00 73.63  ?  285 LEU B N   1 
ATOM   4582 C CA  . LEU B 2 282 ? 114.089 120.546 160.075 1.00 71.73  ?  285 LEU B CA  1 
ATOM   4583 C C   . LEU B 2 282 ? 114.545 120.575 158.625 1.00 68.28  ?  285 LEU B C   1 
ATOM   4584 O O   . LEU B 2 282 ? 113.885 120.004 157.754 1.00 75.80  ?  285 LEU B O   1 
ATOM   4585 C CB  . LEU B 2 282 ? 114.006 119.112 160.594 1.00 65.66  ?  285 LEU B CB  1 
ATOM   4586 C CG  . LEU B 2 282 ? 115.211 118.216 160.318 1.00 73.85  ?  285 LEU B CG  1 
ATOM   4587 C CD1 . LEU B 2 282 ? 116.443 118.745 161.019 1.00 71.66  ?  285 LEU B CD1 1 
ATOM   4588 C CD2 . LEU B 2 282 ? 114.921 116.805 160.759 1.00 70.15  ?  285 LEU B CD2 1 
ATOM   4589 N N   . LEU B 2 283 ? 115.662 121.242 158.370 1.00 62.45  ?  286 LEU B N   1 
ATOM   4590 C CA  . LEU B 2 283 ? 116.191 121.414 157.026 1.00 69.87  ?  286 LEU B CA  1 
ATOM   4591 C C   . LEU B 2 283 ? 117.400 120.512 156.841 1.00 75.82  ?  286 LEU B C   1 
ATOM   4592 O O   . LEU B 2 283 ? 118.350 120.579 157.624 1.00 91.83  ?  286 LEU B O   1 
ATOM   4593 C CB  . LEU B 2 283 ? 116.573 122.873 156.775 1.00 64.05  ?  286 LEU B CB  1 
ATOM   4594 C CG  . LEU B 2 283 ? 115.421 123.876 156.770 1.00 71.11  ?  286 LEU B CG  1 
ATOM   4595 C CD1 . LEU B 2 283 ? 115.298 124.561 158.112 1.00 75.16  ?  286 LEU B CD1 1 
ATOM   4596 C CD2 . LEU B 2 283 ? 115.620 124.894 155.671 1.00 79.55  ?  286 LEU B CD2 1 
ATOM   4597 N N   . ALA B 2 284 ? 117.366 119.680 155.806 1.00 65.25  ?  287 ALA B N   1 
ATOM   4598 C CA  . ALA B 2 284 ? 118.416 118.712 155.538 1.00 57.22  ?  287 ALA B CA  1 
ATOM   4599 C C   . ALA B 2 284 ? 118.948 118.898 154.127 1.00 69.29  ?  287 ALA B C   1 
ATOM   4600 O O   . ALA B 2 284 ? 118.177 119.115 153.191 1.00 87.87  ?  287 ALA B O   1 
ATOM   4601 C CB  . ALA B 2 284 ? 117.901 117.286 155.716 1.00 68.42  ?  287 ALA B CB  1 
ATOM   4602 N N   . GLY B 2 285 ? 120.267 118.809 153.976 1.00 74.91  ?  288 GLY B N   1 
ATOM   4603 C CA  . GLY B 2 285 ? 120.908 118.931 152.679 1.00 63.02  ?  288 GLY B CA  1 
ATOM   4604 C C   . GLY B 2 285 ? 121.293 117.565 152.142 1.00 77.53  ?  288 GLY B C   1 
ATOM   4605 O O   . GLY B 2 285 ? 121.983 116.795 152.811 1.00 88.99  ?  288 GLY B O   1 
ATOM   4606 N N   . TYR B 2 286 ? 120.848 117.282 150.924 1.00 80.20  ?  289 TYR B N   1 
ATOM   4607 C CA  . TYR B 2 286 ? 120.961 115.960 150.328 1.00 75.33  ?  289 TYR B CA  1 
ATOM   4608 C C   . TYR B 2 286 ? 121.950 115.961 149.171 1.00 76.98  ?  289 TYR B C   1 
ATOM   4609 O O   . TYR B 2 286 ? 122.484 116.997 148.774 1.00 84.78  ?  289 TYR B O   1 
ATOM   4610 C CB  . TYR B 2 286 ? 119.596 115.474 149.839 1.00 68.15  ?  289 TYR B CB  1 
ATOM   4611 C CG  . TYR B 2 286 ? 118.592 115.223 150.930 1.00 71.60  ?  289 TYR B CG  1 
ATOM   4612 C CD1 . TYR B 2 286 ? 117.919 116.267 151.534 1.00 75.72  ?  289 TYR B CD1 1 
ATOM   4613 C CD2 . TYR B 2 286 ? 118.320 113.939 151.357 1.00 79.92  ?  289 TYR B CD2 1 
ATOM   4614 C CE1 . TYR B 2 286 ? 117.002 116.034 152.529 1.00 80.28  ?  289 TYR B CE1 1 
ATOM   4615 C CE2 . TYR B 2 286 ? 117.405 113.698 152.348 1.00 80.91  ?  289 TYR B CE2 1 
ATOM   4616 C CZ  . TYR B 2 286 ? 116.750 114.748 152.932 1.00 83.25  ?  289 TYR B CZ  1 
ATOM   4617 O OH  . TYR B 2 286 ? 115.834 114.510 153.926 1.00 84.16  ?  289 TYR B OH  1 
ATOM   4618 N N   . ASP B 2 287 ? 122.195 114.765 148.636 1.00 89.90  ?  290 ASP B N   1 
ATOM   4619 C CA  . ASP B 2 287 ? 122.988 114.596 147.425 1.00 92.82  ?  290 ASP B CA  1 
ATOM   4620 C C   . ASP B 2 287 ? 122.168 114.718 146.147 1.00 99.34  ?  290 ASP B C   1 
ATOM   4621 O O   . ASP B 2 287 ? 122.751 114.700 145.060 1.00 99.59  ?  290 ASP B O   1 
ATOM   4622 C CB  . ASP B 2 287 ? 123.706 113.244 147.441 1.00 92.48  ?  290 ASP B CB  1 
ATOM   4623 C CG  . ASP B 2 287 ? 124.420 112.976 148.746 1.00 99.88  ?  290 ASP B CG  1 
ATOM   4624 O OD1 . ASP B 2 287 ? 124.953 113.932 149.341 1.00 103.11 ?  290 ASP B OD1 1 
ATOM   4625 O OD2 . ASP B 2 287 ? 124.460 111.805 149.173 1.00 98.98  -1 290 ASP B OD2 1 
ATOM   4626 N N   . ASP B 2 288 ? 120.846 114.836 146.244 1.00 107.79 ?  291 ASP B N   1 
ATOM   4627 C CA  . ASP B 2 288 ? 119.988 115.182 145.110 1.00 99.56  ?  291 ASP B CA  1 
ATOM   4628 C C   . ASP B 2 288 ? 120.156 116.578 144.622 1.00 106.92 ?  291 ASP B C   1 
ATOM   4629 O O   . ASP B 2 288 ? 119.355 116.964 143.756 1.00 116.92 ?  291 ASP B O   1 
ATOM   4630 C CB  . ASP B 2 288 ? 118.525 114.879 145.414 1.00 102.60 ?  291 ASP B CB  1 
ATOM   4631 C CG  . ASP B 2 288 ? 118.227 113.402 145.411 1.00 116.58 ?  291 ASP B CG  1 
ATOM   4632 O OD1 . ASP B 2 288 ? 119.107 112.611 145.790 1.00 117.91 ?  291 ASP B OD1 1 
ATOM   4633 O OD2 . ASP B 2 288 ? 117.097 113.024 145.035 1.00 118.40 -1 291 ASP B OD2 1 
ATOM   4634 N N   . PHE B 2 289 ? 121.109 117.334 145.160 1.00 89.30  ?  292 PHE B N   1 
ATOM   4635 C CA  . PHE B 2 289 ? 121.481 118.667 144.707 1.00 90.40  ?  292 PHE B CA  1 
ATOM   4636 C C   . PHE B 2 289 ? 120.521 119.673 145.324 1.00 95.72  ?  292 PHE B C   1 
ATOM   4637 O O   . PHE B 2 289 ? 120.542 120.850 144.947 1.00 102.32 ?  292 PHE B O   1 
ATOM   4638 C CB  . PHE B 2 289 ? 121.461 118.840 143.183 1.00 93.82  ?  292 PHE B CB  1 
ATOM   4639 C CG  . PHE B 2 289 ? 122.512 118.046 142.453 1.00 94.02  ?  292 PHE B CG  1 
ATOM   4640 C CD1 . PHE B 2 289 ? 123.319 117.141 143.115 1.00 96.67  ?  292 PHE B CD1 1 
ATOM   4641 C CD2 . PHE B 2 289 ? 122.673 118.197 141.090 1.00 93.79  ?  292 PHE B CD2 1 
ATOM   4642 C CE1 . PHE B 2 289 ? 124.269 116.417 142.431 1.00 97.91  ?  292 PHE B CE1 1 
ATOM   4643 C CE2 . PHE B 2 289 ? 123.623 117.478 140.405 1.00 99.53  ?  292 PHE B CE2 1 
ATOM   4644 C CZ  . PHE B 2 289 ? 124.421 116.587 141.074 1.00 98.45  ?  292 PHE B CZ  1 
ATOM   4645 N N   . ASN B 2 290 ? 119.670 119.250 146.254 1.00 83.75  ?  293 ASN B N   1 
ATOM   4646 C CA  . ASN B 2 290 ? 118.666 120.137 146.814 1.00 84.53  ?  293 ASN B CA  1 
ATOM   4647 C C   . ASN B 2 290 ? 118.481 119.832 148.291 1.00 87.86  ?  293 ASN B C   1 
ATOM   4648 O O   . ASN B 2 290 ? 118.854 118.765 148.779 1.00 91.98  ?  293 ASN B O   1 
ATOM   4649 C CB  . ASN B 2 290 ? 117.341 120.036 146.043 1.00 86.99  ?  293 ASN B CB  1 
ATOM   4650 C CG  . ASN B 2 290 ? 116.559 118.773 146.356 1.00 97.64  ?  293 ASN B CG  1 
ATOM   4651 O OD1 . ASN B 2 290 ? 117.097 117.793 146.872 1.00 106.77 ?  293 ASN B OD1 1 
ATOM   4652 N ND2 . ASN B 2 290 ? 115.276 118.789 146.031 1.00 91.06  ?  293 ASN B ND2 1 
ATOM   4653 N N   . CYS B 2 291 ? 117.913 120.798 149.002 1.00 80.60  ?  294 CYS B N   1 
ATOM   4654 C CA  . CYS B 2 291 ? 117.692 120.702 150.435 1.00 78.63  ?  294 CYS B CA  1 
ATOM   4655 C C   . CYS B 2 291 ? 116.203 120.579 150.710 1.00 78.57  ?  294 CYS B C   1 
ATOM   4656 O O   . CYS B 2 291 ? 115.405 121.355 150.180 1.00 91.64  ?  294 CYS B O   1 
ATOM   4657 C CB  . CYS B 2 291 ? 118.265 121.923 151.156 1.00 81.03  ?  294 CYS B CB  1 
ATOM   4658 S SG  . CYS B 2 291 ? 117.309 122.461 152.584 1.00 99.36  ?  294 CYS B SG  1 
ATOM   4659 N N   . ASN B 2 292 ? 115.834 119.606 151.534 1.00 73.67  ?  295 ASN B N   1 
ATOM   4660 C CA  . ASN B 2 292 ? 114.454 119.411 151.945 1.00 74.22  ?  295 ASN B CA  1 
ATOM   4661 C C   . ASN B 2 292 ? 114.236 120.038 153.313 1.00 78.41  ?  295 ASN B C   1 
ATOM   4662 O O   . ASN B 2 292 ? 115.134 120.037 154.157 1.00 95.40  ?  295 ASN B O   1 
ATOM   4663 C CB  . ASN B 2 292 ? 114.101 117.926 152.003 1.00 79.65  ?  295 ASN B CB  1 
ATOM   4664 C CG  . ASN B 2 292 ? 113.682 117.374 150.663 1.00 89.64  ?  295 ASN B CG  1 
ATOM   4665 O OD1 . ASN B 2 292 ? 112.497 117.177 150.406 1.00 93.32  ?  295 ASN B OD1 1 
ATOM   4666 N ND2 . ASN B 2 292 ? 114.654 117.111 149.802 1.00 86.10  ?  295 ASN B ND2 1 
ATOM   4667 N N   . VAL B 2 293 ? 113.043 120.580 153.526 1.00 74.79  ?  296 VAL B N   1 
ATOM   4668 C CA  . VAL B 2 293 ? 112.635 121.098 154.825 1.00 79.60  ?  296 VAL B CA  1 
ATOM   4669 C C   . VAL B 2 293 ? 111.468 120.257 155.315 1.00 77.87  ?  296 VAL B C   1 
ATOM   4670 O O   . VAL B 2 293 ? 110.471 120.088 154.604 1.00 80.93  ?  296 VAL B O   1 
ATOM   4671 C CB  . VAL B 2 293 ? 112.279 122.594 154.759 1.00 76.79  ?  296 VAL B CB  1 
ATOM   4672 C CG1 . VAL B 2 293 ? 111.935 122.999 153.351 1.00 76.87  ?  296 VAL B CG1 1 
ATOM   4673 C CG2 . VAL B 2 293 ? 111.146 122.930 155.711 1.00 73.67  ?  296 VAL B CG2 1 
ATOM   4674 N N   . TRP B 2 294 ? 111.606 119.710 156.518 1.00 81.40  ?  297 TRP B N   1 
ATOM   4675 C CA  . TRP B 2 294 ? 110.648 118.778 157.084 1.00 69.17  ?  297 TRP B CA  1 
ATOM   4676 C C   . TRP B 2 294 ? 109.876 119.433 158.218 1.00 70.51  ?  297 TRP B C   1 
ATOM   4677 O O   . TRP B 2 294 ? 110.384 120.318 158.907 1.00 93.41  ?  297 TRP B O   1 
ATOM   4678 C CB  . TRP B 2 294 ? 111.345 117.525 157.621 1.00 73.25  ?  297 TRP B CB  1 
ATOM   4679 C CG  . TRP B 2 294 ? 112.097 116.759 156.596 1.00 74.46  ?  297 TRP B CG  1 
ATOM   4680 C CD1 . TRP B 2 294 ? 113.349 117.020 156.137 1.00 73.83  ?  297 TRP B CD1 1 
ATOM   4681 C CD2 . TRP B 2 294 ? 111.646 115.598 155.899 1.00 71.94  ?  297 TRP B CD2 1 
ATOM   4682 N NE1 . TRP B 2 294 ? 113.708 116.094 155.194 1.00 69.85  ?  297 TRP B NE1 1 
ATOM   4683 C CE2 . TRP B 2 294 ? 112.676 115.210 155.029 1.00 74.51  ?  297 TRP B CE2 1 
ATOM   4684 C CE3 . TRP B 2 294 ? 110.468 114.850 155.925 1.00 71.66  ?  297 TRP B CE3 1 
ATOM   4685 C CZ2 . TRP B 2 294 ? 112.565 114.108 154.193 1.00 78.38  ?  297 TRP B CZ2 1 
ATOM   4686 C CZ3 . TRP B 2 294 ? 110.361 113.760 155.098 1.00 72.44  ?  297 TRP B CZ3 1 
ATOM   4687 C CH2 . TRP B 2 294 ? 111.401 113.397 154.243 1.00 78.76  ?  297 TRP B CH2 1 
ATOM   4688 N N   . ASP B 2 295 ? 108.643 118.983 158.408 1.00 81.76  ?  298 ASP B N   1 
ATOM   4689 C CA  . ASP B 2 295 ? 107.888 119.314 159.607 1.00 84.81  ?  298 ASP B CA  1 
ATOM   4690 C C   . ASP B 2 295 ? 108.413 118.438 160.735 1.00 92.16  ?  298 ASP B C   1 
ATOM   4691 O O   . ASP B 2 295 ? 108.167 117.229 160.754 1.00 100.21 ?  298 ASP B O   1 
ATOM   4692 C CB  . ASP B 2 295 ? 106.398 119.096 159.374 1.00 93.04  ?  298 ASP B CB  1 
ATOM   4693 C CG  . ASP B 2 295 ? 105.538 119.755 160.426 1.00 97.91  ?  298 ASP B CG  1 
ATOM   4694 O OD1 . ASP B 2 295 ? 106.070 120.125 161.491 1.00 99.60  ?  298 ASP B OD1 1 
ATOM   4695 O OD2 . ASP B 2 295 ? 104.324 119.903 160.190 1.00 101.49 -1 298 ASP B OD2 1 
ATOM   4696 N N   . ALA B 2 296 ? 109.142 119.043 161.675 1.00 88.30  ?  299 ALA B N   1 
ATOM   4697 C CA  . ALA B 2 296 ? 109.835 118.270 162.697 1.00 84.93  ?  299 ALA B CA  1 
ATOM   4698 C C   . ALA B 2 296 ? 108.887 117.460 163.566 1.00 87.03  ?  299 ALA B C   1 
ATOM   4699 O O   . ALA B 2 296 ? 109.304 116.451 164.140 1.00 99.51  ?  299 ALA B O   1 
ATOM   4700 C CB  . ALA B 2 296 ? 110.677 119.194 163.575 1.00 82.80  ?  299 ALA B CB  1 
ATOM   4701 N N   . LEU B 2 297 ? 107.629 117.873 163.680 1.00 87.14  ?  300 LEU B N   1 
ATOM   4702 C CA  . LEU B 2 297 ? 106.654 117.141 164.476 1.00 93.01  ?  300 LEU B CA  1 
ATOM   4703 C C   . LEU B 2 297 ? 105.760 116.236 163.645 1.00 101.82 ?  300 LEU B C   1 
ATOM   4704 O O   . LEU B 2 297 ? 105.161 115.306 164.192 1.00 107.41 ?  300 LEU B O   1 
ATOM   4705 C CB  . LEU B 2 297 ? 105.783 118.117 165.271 1.00 99.39  ?  300 LEU B CB  1 
ATOM   4706 C CG  . LEU B 2 297 ? 106.532 119.171 166.087 1.00 99.77  ?  300 LEU B CG  1 
ATOM   4707 C CD1 . LEU B 2 297 ? 105.557 120.067 166.823 1.00 102.77 ?  300 LEU B CD1 1 
ATOM   4708 C CD2 . LEU B 2 297 ? 107.486 118.512 167.060 1.00 96.26  ?  300 LEU B CD2 1 
ATOM   4709 N N   . LYS B 2 298 ? 105.651 116.488 162.342 1.00 105.19 ?  301 LYS B N   1 
ATOM   4710 C CA  . LYS B 2 298 ? 104.799 115.697 161.465 1.00 103.12 ?  301 LYS B CA  1 
ATOM   4711 C C   . LYS B 2 298 ? 105.576 114.730 160.583 1.00 101.14 ?  301 LYS B C   1 
ATOM   4712 O O   . LYS B 2 298 ? 105.000 113.735 160.131 1.00 104.46 ?  301 LYS B O   1 
ATOM   4713 C CB  . LYS B 2 298 ? 103.965 116.622 160.576 1.00 108.65 ?  301 LYS B CB  1 
ATOM   4714 C CG  . LYS B 2 298 ? 102.764 117.252 161.251 1.00 101.96 ?  301 LYS B CG  1 
ATOM   4715 C CD  . LYS B 2 298 ? 101.905 116.211 161.928 1.00 102.52 ?  301 LYS B CD  1 
ATOM   4716 C CE  . LYS B 2 298 ? 100.489 116.714 162.082 1.00 105.51 ?  301 LYS B CE  1 
ATOM   4717 N NZ  . LYS B 2 298 ? 100.476 118.038 162.748 1.00 112.45 1  301 LYS B NZ  1 
ATOM   4718 N N   . ALA B 2 299 ? 106.853 115.010 160.319 1.00 99.24  ?  302 ALA B N   1 
ATOM   4719 C CA  . ALA B 2 299 ? 107.716 114.159 159.495 1.00 103.59 ?  302 ALA B CA  1 
ATOM   4720 C C   . ALA B 2 299 ? 107.213 114.058 158.058 1.00 108.10 ?  302 ALA B C   1 
ATOM   4721 O O   . ALA B 2 299 ? 107.137 112.974 157.478 1.00 108.80 ?  302 ALA B O   1 
ATOM   4722 C CB  . ALA B 2 299 ? 107.879 112.768 160.106 1.00 101.18 ?  302 ALA B CB  1 
ATOM   4723 N N   . ASP B 2 300 ? 106.877 115.205 157.477 1.00 98.87  ?  303 ASP B N   1 
ATOM   4724 C CA  . ASP B 2 300 ? 106.537 115.274 156.065 1.00 99.65  ?  303 ASP B CA  1 
ATOM   4725 C C   . ASP B 2 300 ? 107.230 116.474 155.444 1.00 96.40  ?  303 ASP B C   1 
ATOM   4726 O O   . ASP B 2 300 ? 107.508 117.466 156.120 1.00 105.39 ?  303 ASP B O   1 
ATOM   4727 C CB  . ASP B 2 300 ? 105.026 115.362 155.845 1.00 100.36 ?  303 ASP B CB  1 
ATOM   4728 C CG  . ASP B 2 300 ? 104.344 116.232 156.865 1.00 102.18 ?  303 ASP B CG  1 
ATOM   4729 O OD1 . ASP B 2 300 ? 104.636 117.443 156.904 1.00 103.69 ?  303 ASP B OD1 1 
ATOM   4730 O OD2 . ASP B 2 300 ? 103.520 115.701 157.633 1.00 100.93 -1 303 ASP B OD2 1 
ATOM   4731 N N   . ARG B 2 301 ? 107.510 116.370 154.149 1.00 92.50  ?  304 ARG B N   1 
ATOM   4732 C CA  . ARG B 2 301 ? 108.220 117.424 153.435 1.00 94.15  ?  304 ARG B CA  1 
ATOM   4733 C C   . ARG B 2 301 ? 107.346 118.668 153.365 1.00 104.55 ?  304 ARG B C   1 
ATOM   4734 O O   . ARG B 2 301 ? 106.314 118.674 152.688 1.00 107.98 ?  304 ARG B O   1 
ATOM   4735 C CB  . ARG B 2 301 ? 108.601 116.948 152.039 1.00 92.27  ?  304 ARG B CB  1 
ATOM   4736 C CG  . ARG B 2 301 ? 109.837 116.083 152.000 1.00 95.88  ?  304 ARG B CG  1 
ATOM   4737 C CD  . ARG B 2 301 ? 109.891 115.261 150.728 1.00 99.70  ?  304 ARG B CD  1 
ATOM   4738 N NE  . ARG B 2 301 ? 110.380 116.040 149.598 1.00 107.95 ?  304 ARG B NE  1 
ATOM   4739 C CZ  . ARG B 2 301 ? 110.736 115.521 148.432 1.00 107.65 ?  304 ARG B CZ  1 
ATOM   4740 N NH1 . ARG B 2 301 ? 110.672 114.220 148.207 1.00 105.88 1  304 ARG B NH1 1 
ATOM   4741 N NH2 . ARG B 2 301 ? 111.168 116.327 147.467 1.00 101.29 ?  304 ARG B NH2 1 
ATOM   4742 N N   . ALA B 2 302 ? 107.751 119.721 154.070 1.00 101.09 ?  305 ALA B N   1 
ATOM   4743 C CA  . ALA B 2 302 ? 107.042 120.988 154.008 1.00 92.27  ?  305 ALA B CA  1 
ATOM   4744 C C   . ALA B 2 302 ? 107.489 121.857 152.844 1.00 97.47  ?  305 ALA B C   1 
ATOM   4745 O O   . ALA B 2 302 ? 106.827 122.856 152.550 1.00 103.33 ?  305 ALA B O   1 
ATOM   4746 C CB  . ALA B 2 302 ? 107.222 121.755 155.317 1.00 96.40  ?  305 ALA B CB  1 
ATOM   4747 N N   . GLY B 2 303 ? 108.580 121.505 152.179 1.00 86.24  ?  306 GLY B N   1 
ATOM   4748 C CA  . GLY B 2 303 ? 109.066 122.306 151.073 1.00 82.90  ?  306 GLY B CA  1 
ATOM   4749 C C   . GLY B 2 303 ? 110.367 121.742 150.555 1.00 82.54  ?  306 GLY B C   1 
ATOM   4750 O O   . GLY B 2 303 ? 110.884 120.743 151.059 1.00 95.43  ?  306 GLY B O   1 
ATOM   4751 N N   . VAL B 2 304 ? 110.890 122.402 149.529 1.00 73.88  ?  307 VAL B N   1 
ATOM   4752 C CA  . VAL B 2 304 ? 112.139 122.007 148.893 1.00 72.14  ?  307 VAL B CA  1 
ATOM   4753 C C   . VAL B 2 304 ? 112.936 123.265 148.584 1.00 84.12  ?  307 VAL B C   1 
ATOM   4754 O O   . VAL B 2 304 ? 112.380 124.266 148.122 1.00 90.85  ?  307 VAL B O   1 
ATOM   4755 C CB  . VAL B 2 304 ? 111.881 121.184 147.613 1.00 76.19  ?  307 VAL B CB  1 
ATOM   4756 C CG1 . VAL B 2 304 ? 113.092 121.196 146.711 1.00 83.07  ?  307 VAL B CG1 1 
ATOM   4757 C CG2 . VAL B 2 304 ? 111.505 119.761 147.966 1.00 79.63  ?  307 VAL B CG2 1 
ATOM   4758 N N   . LEU B 2 305 ? 114.237 123.221 148.854 1.00 78.30  ?  308 LEU B N   1 
ATOM   4759 C CA  . LEU B 2 305 ? 115.150 124.311 148.525 1.00 73.70  ?  308 LEU B CA  1 
ATOM   4760 C C   . LEU B 2 305 ? 116.034 123.832 147.379 1.00 80.37  ?  308 LEU B C   1 
ATOM   4761 O O   . LEU B 2 305 ? 117.151 123.358 147.583 1.00 88.98  ?  308 LEU B O   1 
ATOM   4762 C CB  . LEU B 2 305 ? 115.974 124.719 149.742 1.00 75.24  ?  308 LEU B CB  1 
ATOM   4763 C CG  . LEU B 2 305 ? 115.464 125.861 150.619 1.00 78.07  ?  308 LEU B CG  1 
ATOM   4764 C CD1 . LEU B 2 305 ? 114.015 125.656 150.996 1.00 74.34  ?  308 LEU B CD1 1 
ATOM   4765 C CD2 . LEU B 2 305 ? 116.321 125.979 151.859 1.00 83.34  ?  308 LEU B CD2 1 
ATOM   4766 N N   . ALA B 2 306 ? 115.531 123.978 146.159 1.00 83.19  ?  309 ALA B N   1 
ATOM   4767 C CA  . ALA B 2 306 ? 116.201 123.484 144.959 1.00 81.66  ?  309 ALA B CA  1 
ATOM   4768 C C   . ALA B 2 306 ? 116.757 124.671 144.184 1.00 79.24  ?  309 ALA B C   1 
ATOM   4769 O O   . ALA B 2 306 ? 116.033 125.319 143.425 1.00 86.86  ?  309 ALA B O   1 
ATOM   4770 C CB  . ALA B 2 306 ? 115.244 122.666 144.101 1.00 76.70  ?  309 ALA B CB  1 
ATOM   4771 N N   . GLY B 2 307 ? 118.037 124.960 144.383 1.00 85.42  ?  310 GLY B N   1 
ATOM   4772 C CA  . GLY B 2 307 ? 118.685 126.008 143.624 1.00 83.43  ?  310 GLY B CA  1 
ATOM   4773 C C   . GLY B 2 307 ? 120.137 125.732 143.304 1.00 86.98  ?  310 GLY B C   1 
ATOM   4774 O O   . GLY B 2 307 ? 120.828 126.596 142.760 1.00 91.33  ?  310 GLY B O   1 
ATOM   4775 N N   . HIS B 2 308 ? 120.612 124.534 143.619 1.00 82.66  ?  311 HIS B N   1 
ATOM   4776 C CA  . HIS B 2 308 ? 122.017 124.187 143.472 1.00 81.46  ?  311 HIS B CA  1 
ATOM   4777 C C   . HIS B 2 308 ? 122.190 123.155 142.368 1.00 81.37  ?  311 HIS B C   1 
ATOM   4778 O O   . HIS B 2 308 ? 121.347 122.272 142.191 1.00 86.21  ?  311 HIS B O   1 
ATOM   4779 C CB  . HIS B 2 308 ? 122.589 123.651 144.785 1.00 86.10  ?  311 HIS B CB  1 
ATOM   4780 C CG  . HIS B 2 308 ? 122.770 124.697 145.840 1.00 86.59  ?  311 HIS B CG  1 
ATOM   4781 N ND1 . HIS B 2 308 ? 123.748 125.665 145.771 1.00 78.67  ?  311 HIS B ND1 1 
ATOM   4782 C CD2 . HIS B 2 308 ? 122.096 124.927 146.991 1.00 83.75  ?  311 HIS B CD2 1 
ATOM   4783 C CE1 . HIS B 2 308 ? 123.670 126.443 146.834 1.00 74.70  ?  311 HIS B CE1 1 
ATOM   4784 N NE2 . HIS B 2 308 ? 122.675 126.017 147.590 1.00 86.28  ?  311 HIS B NE2 1 
ATOM   4785 N N   . ASP B 2 309 ? 123.285 123.279 141.624 1.00 98.92  ?  312 ASP B N   1 
ATOM   4786 C CA  . ASP B 2 309 ? 123.595 122.376 140.525 1.00 100.86 ?  312 ASP B CA  1 
ATOM   4787 C C   . ASP B 2 309 ? 124.484 121.217 140.945 1.00 101.44 ?  312 ASP B C   1 
ATOM   4788 O O   . ASP B 2 309 ? 124.877 120.416 140.091 1.00 107.17 ?  312 ASP B O   1 
ATOM   4789 C CB  . ASP B 2 309 ? 124.267 123.146 139.385 1.00 105.67 ?  312 ASP B CB  1 
ATOM   4790 C CG  . ASP B 2 309 ? 123.391 124.250 138.833 1.00 114.66 ?  312 ASP B CG  1 
ATOM   4791 O OD1 . ASP B 2 309 ? 122.183 124.007 138.626 1.00 111.87 ?  312 ASP B OD1 1 
ATOM   4792 O OD2 . ASP B 2 309 ? 123.910 125.362 138.609 1.00 118.52 -1 312 ASP B OD2 1 
ATOM   4793 N N   . ASN B 2 310 ? 124.822 121.114 142.225 1.00 83.99  ?  313 ASN B N   1 
ATOM   4794 C CA  . ASN B 2 310 ? 125.608 120.000 142.727 1.00 82.30  ?  313 ASN B CA  1 
ATOM   4795 C C   . ASN B 2 310 ? 125.147 119.690 144.143 1.00 90.89  ?  313 ASN B C   1 
ATOM   4796 O O   . ASN B 2 310 ? 124.203 120.295 144.655 1.00 88.74  ?  313 ASN B O   1 
ATOM   4797 C CB  . ASN B 2 310 ? 127.105 120.306 142.673 1.00 77.81  ?  313 ASN B CB  1 
ATOM   4798 C CG  . ASN B 2 310 ? 127.940 119.073 142.425 1.00 80.16  ?  313 ASN B CG  1 
ATOM   4799 O OD1 . ASN B 2 310 ? 127.557 117.969 142.799 1.00 88.09  ?  313 ASN B OD1 1 
ATOM   4800 N ND2 . ASN B 2 310 ? 129.090 119.253 141.794 1.00 85.81  ?  313 ASN B ND2 1 
ATOM   4801 N N   . ARG B 2 311 ? 125.826 118.738 144.774 1.00 97.82  ?  314 ARG B N   1 
ATOM   4802 C CA  . ARG B 2 311 ? 125.429 118.279 146.097 1.00 89.20  ?  314 ARG B CA  1 
ATOM   4803 C C   . ARG B 2 311 ? 125.527 119.408 147.113 1.00 90.49  ?  314 ARG B C   1 
ATOM   4804 O O   . ARG B 2 311 ? 126.511 120.148 147.143 1.00 106.11 ?  314 ARG B O   1 
ATOM   4805 C CB  . ARG B 2 311 ? 126.308 117.102 146.519 1.00 84.80  ?  314 ARG B CB  1 
ATOM   4806 C CG  . ARG B 2 311 ? 126.462 116.938 148.012 1.00 90.42  ?  314 ARG B CG  1 
ATOM   4807 C CD  . ARG B 2 311 ? 127.663 116.084 148.354 1.00 87.63  ?  314 ARG B CD  1 
ATOM   4808 N NE  . ARG B 2 311 ? 127.580 114.759 147.751 1.00 93.89  ?  314 ARG B NE  1 
ATOM   4809 C CZ  . ARG B 2 311 ? 128.150 113.674 148.254 1.00 94.55  ?  314 ARG B CZ  1 
ATOM   4810 N NH1 . ARG B 2 311 ? 128.841 113.716 149.380 1.00 93.88  1  314 ARG B NH1 1 
ATOM   4811 N NH2 . ARG B 2 311 ? 128.022 112.517 147.612 1.00 86.79  ?  314 ARG B NH2 1 
ATOM   4812 N N   . VAL B 2 312 ? 124.497 119.540 147.945 1.00 74.07  ?  315 VAL B N   1 
ATOM   4813 C CA  . VAL B 2 312 ? 124.488 120.532 149.016 1.00 77.12  ?  315 VAL B CA  1 
ATOM   4814 C C   . VAL B 2 312 ? 125.331 119.985 150.162 1.00 84.71  ?  315 VAL B C   1 
ATOM   4815 O O   . VAL B 2 312 ? 124.934 119.032 150.834 1.00 86.65  ?  315 VAL B O   1 
ATOM   4816 C CB  . VAL B 2 312 ? 123.062 120.848 149.477 1.00 70.89  ?  315 VAL B CB  1 
ATOM   4817 C CG1 . VAL B 2 312 ? 123.087 121.712 150.719 1.00 76.38  ?  315 VAL B CG1 1 
ATOM   4818 C CG2 . VAL B 2 312 ? 122.294 121.535 148.376 1.00 79.65  ?  315 VAL B CG2 1 
ATOM   4819 N N   . SER B 2 313 ? 126.495 120.588 150.391 1.00 76.58  ?  316 SER B N   1 
ATOM   4820 C CA  . SER B 2 313 ? 127.455 120.057 151.349 1.00 75.49  ?  316 SER B CA  1 
ATOM   4821 C C   . SER B 2 313 ? 127.345 120.673 152.733 1.00 78.81  ?  316 SER B C   1 
ATOM   4822 O O   . SER B 2 313 ? 127.651 119.999 153.720 1.00 88.14  ?  316 SER B O   1 
ATOM   4823 C CB  . SER B 2 313 ? 128.880 120.255 150.831 1.00 75.10  ?  316 SER B CB  1 
ATOM   4824 O OG  . SER B 2 313 ? 129.076 121.585 150.402 1.00 85.76  ?  316 SER B OG  1 
ATOM   4825 N N   . CYS B 2 314 ? 126.929 121.931 152.834 1.00 73.92  ?  317 CYS B N   1 
ATOM   4826 C CA  . CYS B 2 314 ? 126.813 122.605 154.116 1.00 69.39  ?  317 CYS B CA  1 
ATOM   4827 C C   . CYS B 2 314 ? 125.514 123.390 154.143 1.00 71.03  ?  317 CYS B C   1 
ATOM   4828 O O   . CYS B 2 314 ? 124.943 123.718 153.102 1.00 79.43  ?  317 CYS B O   1 
ATOM   4829 C CB  . CYS B 2 314 ? 128.001 123.534 154.377 1.00 73.72  ?  317 CYS B CB  1 
ATOM   4830 S SG  . CYS B 2 314 ? 128.584 124.419 152.925 1.00 95.26  ?  317 CYS B SG  1 
ATOM   4831 N N   . LEU B 2 315 ? 125.052 123.689 155.352 1.00 69.83  ?  318 LEU B N   1 
ATOM   4832 C CA  . LEU B 2 315 ? 123.762 124.339 155.522 1.00 69.60  ?  318 LEU B CA  1 
ATOM   4833 C C   . LEU B 2 315 ? 123.645 124.825 156.956 1.00 75.53  ?  318 LEU B C   1 
ATOM   4834 O O   . LEU B 2 315 ? 124.036 124.116 157.885 1.00 91.33  ?  318 LEU B O   1 
ATOM   4835 C CB  . LEU B 2 315 ? 122.629 123.369 155.156 1.00 65.62  ?  318 LEU B CB  1 
ATOM   4836 C CG  . LEU B 2 315 ? 121.162 123.568 155.514 1.00 66.83  ?  318 LEU B CG  1 
ATOM   4837 C CD1 . LEU B 2 315 ? 120.335 122.769 154.552 1.00 74.99  ?  318 LEU B CD1 1 
ATOM   4838 C CD2 . LEU B 2 315 ? 120.896 123.062 156.894 1.00 64.83  ?  318 LEU B CD2 1 
ATOM   4839 N N   . GLY B 2 316 ? 123.118 126.033 157.129 1.00 59.65  ?  319 GLY B N   1 
ATOM   4840 C CA  . GLY B 2 316 ? 122.963 126.602 158.454 1.00 60.95  ?  319 GLY B CA  1 
ATOM   4841 C C   . GLY B 2 316 ? 121.828 127.600 158.499 1.00 66.06  ?  319 GLY B C   1 
ATOM   4842 O O   . GLY B 2 316 ? 121.411 128.146 157.475 1.00 83.55  ?  319 GLY B O   1 
ATOM   4843 N N   . VAL B 2 317 ? 121.331 127.832 159.709 1.00 64.60  ?  320 VAL B N   1 
ATOM   4844 C CA  . VAL B 2 317 ? 120.246 128.770 159.963 1.00 63.73  ?  320 VAL B CA  1 
ATOM   4845 C C   . VAL B 2 317 ? 120.750 129.834 160.926 1.00 71.61  ?  320 VAL B C   1 
ATOM   4846 O O   . VAL B 2 317 ? 121.452 129.522 161.893 1.00 77.21  ?  320 VAL B O   1 
ATOM   4847 C CB  . VAL B 2 317 ? 119.001 128.059 160.530 1.00 58.48  ?  320 VAL B CB  1 
ATOM   4848 C CG1 . VAL B 2 317 ? 117.890 129.055 160.803 1.00 62.85  ?  320 VAL B CG1 1 
ATOM   4849 C CG2 . VAL B 2 317 ? 118.523 126.991 159.571 1.00 57.64  ?  320 VAL B CG2 1 
ATOM   4850 N N   . THR B 2 318 ? 120.401 131.089 160.655 1.00 79.24  ?  321 THR B N   1 
ATOM   4851 C CA  . THR B 2 318 ? 120.878 132.198 161.467 1.00 79.72  ?  321 THR B CA  1 
ATOM   4852 C C   . THR B 2 318 ? 120.358 132.089 162.896 1.00 84.07  ?  321 THR B C   1 
ATOM   4853 O O   . THR B 2 318 ? 119.386 131.390 163.185 1.00 86.08  ?  321 THR B O   1 
ATOM   4854 C CB  . THR B 2 318 ? 120.445 133.534 160.868 1.00 69.06  ?  321 THR B CB  1 
ATOM   4855 O OG1 . THR B 2 318 ? 119.023 133.659 160.963 1.00 84.57  ?  321 THR B OG1 1 
ATOM   4856 C CG2 . THR B 2 318 ? 120.855 133.629 159.421 1.00 68.90  ?  321 THR B CG2 1 
ATOM   4857 N N   . ASP B 2 319 ? 121.033 132.800 163.802 1.00 95.23  ?  322 ASP B N   1 
ATOM   4858 C CA  . ASP B 2 319 ? 120.640 132.777 165.206 1.00 96.56  ?  322 ASP B CA  1 
ATOM   4859 C C   . ASP B 2 319 ? 119.251 133.366 165.405 1.00 98.59  ?  322 ASP B C   1 
ATOM   4860 O O   . ASP B 2 319 ? 118.476 132.877 166.234 1.00 104.41 ?  322 ASP B O   1 
ATOM   4861 C CB  . ASP B 2 319 ? 121.666 133.524 166.052 1.00 99.33  ?  322 ASP B CB  1 
ATOM   4862 C CG  . ASP B 2 319 ? 122.670 132.598 166.695 1.00 108.42 ?  322 ASP B CG  1 
ATOM   4863 O OD1 . ASP B 2 319 ? 123.132 131.658 166.017 1.00 102.41 ?  322 ASP B OD1 1 
ATOM   4864 O OD2 . ASP B 2 319 ? 122.995 132.805 167.882 1.00 113.26 -1 322 ASP B OD2 1 
ATOM   4865 N N   . ASP B 2 320 ? 118.918 134.421 164.667 1.00 88.08  ?  323 ASP B N   1 
ATOM   4866 C CA  . ASP B 2 320 ? 117.579 134.987 164.746 1.00 82.91  ?  323 ASP B CA  1 
ATOM   4867 C C   . ASP B 2 320 ? 116.578 134.251 163.869 1.00 94.43  ?  323 ASP B C   1 
ATOM   4868 O O   . ASP B 2 320 ? 115.400 134.617 163.862 1.00 102.83 ?  323 ASP B O   1 
ATOM   4869 C CB  . ASP B 2 320 ? 117.600 136.471 164.374 1.00 95.23  ?  323 ASP B CB  1 
ATOM   4870 C CG  . ASP B 2 320 ? 118.325 136.741 163.076 1.00 103.24 ?  323 ASP B CG  1 
ATOM   4871 O OD1 . ASP B 2 320 ? 118.508 135.799 162.283 1.00 106.41 ?  323 ASP B OD1 1 
ATOM   4872 O OD2 . ASP B 2 320 ? 118.705 137.906 162.841 1.00 99.53  -1 323 ASP B OD2 1 
ATOM   4873 N N   . GLY B 2 321 ? 117.016 133.238 163.128 1.00 96.27  ?  324 GLY B N   1 
ATOM   4874 C CA  . GLY B 2 321 ? 116.111 132.444 162.328 1.00 96.06  ?  324 GLY B CA  1 
ATOM   4875 C C   . GLY B 2 321 ? 115.604 133.120 161.082 1.00 92.24  ?  324 GLY B C   1 
ATOM   4876 O O   . GLY B 2 321 ? 114.662 132.619 160.465 1.00 102.85 ?  324 GLY B O   1 
ATOM   4877 N N   . MET B 2 322 ? 116.201 134.242 160.688 1.00 92.32  ?  325 MET B N   1 
ATOM   4878 C CA  . MET B 2 322 ? 115.671 135.013 159.572 1.00 93.75  ?  325 MET B CA  1 
ATOM   4879 C C   . MET B 2 322 ? 115.975 134.375 158.225 1.00 97.60  ?  325 MET B C   1 
ATOM   4880 O O   . MET B 2 322 ? 115.219 134.576 157.272 1.00 107.17 ?  325 MET B O   1 
ATOM   4881 C CB  . MET B 2 322 ? 116.222 136.437 159.616 1.00 96.70  ?  325 MET B CB  1 
ATOM   4882 C CG  . MET B 2 322 ? 115.439 137.428 158.776 1.00 107.92 ?  325 MET B CG  1 
ATOM   4883 S SD  . MET B 2 322 ? 113.804 137.770 159.447 1.00 122.21 ?  325 MET B SD  1 
ATOM   4884 C CE  . MET B 2 322 ? 114.233 138.584 160.980 1.00 98.94  ?  325 MET B CE  1 
ATOM   4885 N N   . ALA B 2 323 ? 117.056 133.608 158.117 1.00 75.22  ?  326 ALA B N   1 
ATOM   4886 C CA  . ALA B 2 323 ? 117.436 133.046 156.832 1.00 65.17  ?  326 ALA B CA  1 
ATOM   4887 C C   . ALA B 2 323 ? 118.184 131.741 157.038 1.00 70.57  ?  326 ALA B C   1 
ATOM   4888 O O   . ALA B 2 323 ? 118.663 131.441 158.131 1.00 74.91  ?  326 ALA B O   1 
ATOM   4889 C CB  . ALA B 2 323 ? 118.298 134.021 156.028 1.00 68.83  ?  326 ALA B CB  1 
ATOM   4890 N N   . VAL B 2 324 ? 118.267 130.962 155.965 1.00 70.98  ?  327 VAL B N   1 
ATOM   4891 C CA  . VAL B 2 324 ? 119.104 129.773 155.912 1.00 68.29  ?  327 VAL B CA  1 
ATOM   4892 C C   . VAL B 2 324 ? 120.082 129.955 154.763 1.00 58.15  ?  327 VAL B C   1 
ATOM   4893 O O   . VAL B 2 324 ? 119.760 130.564 153.740 1.00 79.64  ?  327 VAL B O   1 
ATOM   4894 C CB  . VAL B 2 324 ? 118.284 128.471 155.746 1.00 64.93  ?  327 VAL B CB  1 
ATOM   4895 C CG1 . VAL B 2 324 ? 116.823 128.728 155.995 1.00 65.81  ?  327 VAL B CG1 1 
ATOM   4896 C CG2 . VAL B 2 324 ? 118.489 127.849 154.380 1.00 67.90  ?  327 VAL B CG2 1 
ATOM   4897 N N   . ALA B 2 325 ? 121.296 129.456 154.950 1.00 46.35  ?  328 ALA B N   1 
ATOM   4898 C CA  . ALA B 2 325 ? 122.325 129.506 153.925 1.00 53.31  ?  328 ALA B CA  1 
ATOM   4899 C C   . ALA B 2 325 ? 122.735 128.089 153.579 1.00 58.32  ?  328 ALA B C   1 
ATOM   4900 O O   . ALA B 2 325 ? 122.931 127.263 154.473 1.00 80.90  ?  328 ALA B O   1 
ATOM   4901 C CB  . ALA B 2 325 ? 123.538 130.310 154.386 1.00 62.44  ?  328 ALA B CB  1 
ATOM   4902 N N   . THR B 2 326 ? 122.844 127.803 152.288 1.00 60.83  ?  329 THR B N   1 
ATOM   4903 C CA  . THR B 2 326 ? 123.273 126.500 151.807 1.00 64.42  ?  329 THR B CA  1 
ATOM   4904 C C   . THR B 2 326 ? 124.469 126.683 150.889 1.00 64.91  ?  329 THR B C   1 
ATOM   4905 O O   . THR B 2 326 ? 124.439 127.522 149.987 1.00 82.20  ?  329 THR B O   1 
ATOM   4906 C CB  . THR B 2 326 ? 122.149 125.775 151.060 1.00 75.45  ?  329 THR B CB  1 
ATOM   4907 O OG1 . THR B 2 326 ? 121.877 126.451 149.829 1.00 82.63  ?  329 THR B OG1 1 
ATOM   4908 C CG2 . THR B 2 326 ? 120.885 125.726 151.894 1.00 71.00  ?  329 THR B CG2 1 
ATOM   4909 N N   . GLY B 2 327 ? 125.514 125.905 151.125 1.00 63.15  ?  330 GLY B N   1 
ATOM   4910 C CA  . GLY B 2 327 ? 126.657 125.833 150.231 1.00 65.70  ?  330 GLY B CA  1 
ATOM   4911 C C   . GLY B 2 327 ? 126.632 124.495 149.515 1.00 66.32  ?  330 GLY B C   1 
ATOM   4912 O O   . GLY B 2 327 ? 126.242 123.483 150.098 1.00 75.75  ?  330 GLY B O   1 
ATOM   4913 N N   . SER B 2 328 ? 127.026 124.499 148.253 1.00 76.58  ?  331 SER B N   1 
ATOM   4914 C CA  . SER B 2 328 ? 126.995 123.291 147.446 1.00 75.02  ?  331 SER B CA  1 
ATOM   4915 C C   . SER B 2 328 ? 128.378 123.005 146.888 1.00 71.45  ?  331 SER B C   1 
ATOM   4916 O O   . SER B 2 328 ? 129.328 123.761 147.090 1.00 81.28  ?  331 SER B O   1 
ATOM   4917 C CB  . SER B 2 328 ? 125.974 123.403 146.313 1.00 79.53  ?  331 SER B CB  1 
ATOM   4918 O OG  . SER B 2 328 ? 125.909 124.723 145.810 1.00 96.30  ?  331 SER B OG  1 
ATOM   4919 N N   . TRP B 2 329 ? 128.481 121.885 146.179 1.00 85.58  ?  332 TRP B N   1 
ATOM   4920 C CA  . TRP B 2 329 ? 129.731 121.532 145.530 1.00 85.71  ?  332 TRP B CA  1 
ATOM   4921 C C   . TRP B 2 329 ? 129.986 122.370 144.287 1.00 90.40  ?  332 TRP B C   1 
ATOM   4922 O O   . TRP B 2 329 ? 131.130 122.439 143.828 1.00 87.86  ?  332 TRP B O   1 
ATOM   4923 C CB  . TRP B 2 329 ? 129.737 120.045 145.197 1.00 88.06  ?  332 TRP B CB  1 
ATOM   4924 C CG  . TRP B 2 329 ? 130.225 119.215 146.332 1.00 84.42  ?  332 TRP B CG  1 
ATOM   4925 C CD1 . TRP B 2 329 ? 130.574 119.654 147.570 1.00 85.93  ?  332 TRP B CD1 1 
ATOM   4926 C CD2 . TRP B 2 329 ? 130.424 117.800 146.336 1.00 92.60  ?  332 TRP B CD2 1 
ATOM   4927 N NE1 . TRP B 2 329 ? 130.980 118.602 148.349 1.00 92.49  ?  332 TRP B NE1 1 
ATOM   4928 C CE2 . TRP B 2 329 ? 130.898 117.451 147.612 1.00 97.70  ?  332 TRP B CE2 1 
ATOM   4929 C CE3 . TRP B 2 329 ? 130.253 116.795 145.383 1.00 92.81  ?  332 TRP B CE3 1 
ATOM   4930 C CZ2 . TRP B 2 329 ? 131.198 116.141 147.961 1.00 91.00  ?  332 TRP B CZ2 1 
ATOM   4931 C CZ3 . TRP B 2 329 ? 130.550 115.499 145.732 1.00 92.46  ?  332 TRP B CZ3 1 
ATOM   4932 C CH2 . TRP B 2 329 ? 131.018 115.182 147.008 1.00 90.43  ?  332 TRP B CH2 1 
ATOM   4933 N N   . ASP B 2 330 ? 128.953 122.993 143.725 1.00 86.27  ?  333 ASP B N   1 
ATOM   4934 C CA  . ASP B 2 330 ? 129.191 124.159 142.895 1.00 82.42  ?  333 ASP B CA  1 
ATOM   4935 C C   . ASP B 2 330 ? 129.526 125.342 143.794 1.00 92.62  ?  333 ASP B C   1 
ATOM   4936 O O   . ASP B 2 330 ? 129.000 125.484 144.899 1.00 106.67 ?  333 ASP B O   1 
ATOM   4937 C CB  . ASP B 2 330 ? 127.983 124.470 142.011 1.00 85.17  ?  333 ASP B CB  1 
ATOM   4938 C CG  . ASP B 2 330 ? 126.682 124.502 142.778 1.00 92.39  ?  333 ASP B CG  1 
ATOM   4939 O OD1 . ASP B 2 330 ? 126.536 125.330 143.695 1.00 98.37  ?  333 ASP B OD1 1 
ATOM   4940 O OD2 . ASP B 2 330 ? 125.790 123.696 142.456 1.00 103.25 -1 333 ASP B OD2 1 
ATOM   4941 N N   . SER B 2 331 ? 130.410 126.202 143.315 1.00 77.15  ?  334 SER B N   1 
ATOM   4942 C CA  . SER B 2 331 ? 131.071 127.152 144.204 1.00 81.52  ?  334 SER B CA  1 
ATOM   4943 C C   . SER B 2 331 ? 130.184 128.344 144.546 1.00 91.62  ?  334 SER B C   1 
ATOM   4944 O O   . SER B 2 331 ? 130.602 129.494 144.437 1.00 102.22 ?  334 SER B O   1 
ATOM   4945 C CB  . SER B 2 331 ? 132.367 127.611 143.558 1.00 95.45  ?  334 SER B CB  1 
ATOM   4946 O OG  . SER B 2 331 ? 132.183 127.816 142.169 1.00 97.63  ?  334 SER B OG  1 
ATOM   4947 N N   . PHE B 2 332 ? 128.961 128.083 145.003 1.00 68.49  ?  335 PHE B N   1 
ATOM   4948 C CA  . PHE B 2 332 ? 128.014 129.139 145.327 1.00 76.38  ?  335 PHE B CA  1 
ATOM   4949 C C   . PHE B 2 332 ? 127.343 128.861 146.661 1.00 79.81  ?  335 PHE B C   1 
ATOM   4950 O O   . PHE B 2 332 ? 127.014 127.716 146.976 1.00 86.64  ?  335 PHE B O   1 
ATOM   4951 C CB  . PHE B 2 332 ? 126.931 129.289 144.251 1.00 80.15  ?  335 PHE B CB  1 
ATOM   4952 C CG  . PHE B 2 332 ? 127.467 129.452 142.865 1.00 80.61  ?  335 PHE B CG  1 
ATOM   4953 C CD1 . PHE B 2 332 ? 128.410 130.416 142.582 1.00 81.67  ?  335 PHE B CD1 1 
ATOM   4954 C CD2 . PHE B 2 332 ? 127.028 128.636 141.844 1.00 86.92  ?  335 PHE B CD2 1 
ATOM   4955 C CE1 . PHE B 2 332 ? 128.905 130.561 141.310 1.00 82.26  ?  335 PHE B CE1 1 
ATOM   4956 C CE2 . PHE B 2 332 ? 127.521 128.778 140.571 1.00 91.23  ?  335 PHE B CE2 1 
ATOM   4957 C CZ  . PHE B 2 332 ? 128.460 129.743 140.304 1.00 89.46  ?  335 PHE B CZ  1 
ATOM   4958 N N   . LEU B 2 333 ? 127.142 129.920 147.433 1.00 68.04  ?  336 LEU B N   1 
ATOM   4959 C CA  . LEU B 2 333 ? 126.283 129.896 148.603 1.00 61.97  ?  336 LEU B CA  1 
ATOM   4960 C C   . LEU B 2 333 ? 125.010 130.666 148.294 1.00 69.87  ?  336 LEU B C   1 
ATOM   4961 O O   . LEU B 2 333 ? 125.025 131.645 147.548 1.00 85.29  ?  336 LEU B O   1 
ATOM   4962 C CB  . LEU B 2 333 ? 126.977 130.511 149.817 1.00 59.96  ?  336 LEU B CB  1 
ATOM   4963 C CG  . LEU B 2 333 ? 128.146 129.751 150.430 1.00 69.23  ?  336 LEU B CG  1 
ATOM   4964 C CD1 . LEU B 2 333 ? 129.415 130.548 150.260 1.00 77.67  ?  336 LEU B CD1 1 
ATOM   4965 C CD2 . LEU B 2 333 ? 127.878 129.480 151.893 1.00 68.33  ?  336 LEU B CD2 1 
ATOM   4966 N N   . LYS B 2 334 ? 123.906 130.215 148.868 1.00 65.40  ?  337 LYS B N   1 
ATOM   4967 C CA  . LYS B 2 334 ? 122.621 130.847 148.630 1.00 65.96  ?  337 LYS B CA  1 
ATOM   4968 C C   . LYS B 2 334 ? 121.932 131.075 149.962 1.00 77.14  ?  337 LYS B C   1 
ATOM   4969 O O   . LYS B 2 334 ? 121.903 130.181 150.810 1.00 88.85  ?  337 LYS B O   1 
ATOM   4970 C CB  . LYS B 2 334 ? 121.739 129.988 147.722 1.00 75.49  ?  337 LYS B CB  1 
ATOM   4971 C CG  . LYS B 2 334 ? 122.221 129.899 146.290 1.00 79.92  ?  337 LYS B CG  1 
ATOM   4972 C CD  . LYS B 2 334 ? 121.153 129.311 145.395 1.00 78.33  ?  337 LYS B CD  1 
ATOM   4973 C CE  . LYS B 2 334 ? 121.493 129.510 143.935 1.00 75.89  ?  337 LYS B CE  1 
ATOM   4974 N NZ  . LYS B 2 334 ? 122.919 129.196 143.666 1.00 84.98  1  337 LYS B NZ  1 
ATOM   4975 N N   . ILE B 2 335 ? 121.375 132.267 150.141 1.00 68.00  ?  338 ILE B N   1 
ATOM   4976 C CA  . ILE B 2 335 ? 120.634 132.620 151.344 1.00 61.19  ?  338 ILE B CA  1 
ATOM   4977 C C   . ILE B 2 335 ? 119.154 132.589 151.001 1.00 65.81  ?  338 ILE B C   1 
ATOM   4978 O O   . ILE B 2 335 ? 118.719 133.240 150.046 1.00 85.64  ?  338 ILE B O   1 
ATOM   4979 C CB  . ILE B 2 335 ? 121.054 133.995 151.890 1.00 59.66  ?  338 ILE B CB  1 
ATOM   4980 C CG1 . ILE B 2 335 ? 122.337 133.882 152.711 1.00 62.38  ?  338 ILE B CG1 1 
ATOM   4981 C CG2 . ILE B 2 335 ? 119.962 134.571 152.757 1.00 68.74  ?  338 ILE B CG2 1 
ATOM   4982 C CD1 . ILE B 2 335 ? 123.596 133.876 151.890 1.00 60.76  ?  338 ILE B CD1 1 
ATOM   4983 N N   . TRP B 2 336 ? 118.387 131.822 151.765 1.00 75.95  ?  339 TRP B N   1 
ATOM   4984 C CA  . TRP B 2 336 ? 116.981 131.580 151.485 1.00 65.77  ?  339 TRP B CA  1 
ATOM   4985 C C   . TRP B 2 336 ? 116.131 132.170 152.596 1.00 74.34  ?  339 TRP B C   1 
ATOM   4986 O O   . TRP B 2 336 ? 116.492 132.096 153.772 1.00 93.05  ?  339 TRP B O   1 
ATOM   4987 C CB  . TRP B 2 336 ? 116.697 130.082 151.351 1.00 67.93  ?  339 TRP B CB  1 
ATOM   4988 C CG  . TRP B 2 336 ? 117.633 129.365 150.430 1.00 75.48  ?  339 TRP B CG  1 
ATOM   4989 C CD1 . TRP B 2 336 ? 118.950 129.101 150.643 1.00 75.24  ?  339 TRP B CD1 1 
ATOM   4990 C CD2 . TRP B 2 336 ? 117.315 128.808 149.153 1.00 84.65  ?  339 TRP B CD2 1 
ATOM   4991 N NE1 . TRP B 2 336 ? 119.477 128.424 149.577 1.00 71.32  ?  339 TRP B NE1 1 
ATOM   4992 C CE2 . TRP B 2 336 ? 118.492 128.230 148.647 1.00 77.49  ?  339 TRP B CE2 1 
ATOM   4993 C CE3 . TRP B 2 336 ? 116.150 128.743 148.387 1.00 79.97  ?  339 TRP B CE3 1 
ATOM   4994 C CZ2 . TRP B 2 336 ? 118.538 127.598 147.413 1.00 73.01  ?  339 TRP B CZ2 1 
ATOM   4995 C CZ3 . TRP B 2 336 ? 116.199 128.117 147.165 1.00 74.53  ?  339 TRP B CZ3 1 
ATOM   4996 C CH2 . TRP B 2 336 ? 117.383 127.553 146.688 1.00 81.43  ?  339 TRP B CH2 1 
ATOM   4997 N N   . ASN B 2 337 ? 115.001 132.754 152.222 1.00 97.34  ?  340 ASN B N   1 
ATOM   4998 C CA  . ASN B 2 337 ? 114.119 133.383 153.193 1.00 99.37  ?  340 ASN B CA  1 
ATOM   4999 C C   . ASN B 2 337 ? 112.659 133.070 152.903 1.00 108.18 ?  340 ASN B C   1 
ATOM   5000 O O   . ASN B 2 337 ? 111.838 132.977 153.813 1.00 106.13 ?  340 ASN B O   1 
ATOM   5001 C CB  . ASN B 2 337 ? 114.334 134.892 153.203 1.00 99.78  ?  340 ASN B CB  1 
ATOM   5002 C CG  . ASN B 2 337 ? 114.287 135.474 154.589 1.00 103.19 ?  340 ASN B CG  1 
ATOM   5003 O OD1 . ASN B 2 337 ? 113.287 135.348 155.292 1.00 102.01 ?  340 ASN B OD1 1 
ATOM   5004 N ND2 . ASN B 2 337 ? 115.370 136.120 154.995 1.00 104.82 ?  340 ASN B ND2 1 
ATOM   5005 O OXT . ASN B 2 337 ? 112.264 132.907 151.753 1.00 112.95 -1 340 ASN B OXT 1 
ATOM   5006 N N   . THR C 3 1   ? 123.424 155.210 146.099 1.00 100.19 ?  4   THR C N   1 
ATOM   5007 C CA  . THR C 3 1   ? 122.609 155.226 147.308 1.00 110.21 ?  4   THR C CA  1 
ATOM   5008 C C   . THR C 3 1   ? 123.411 154.785 148.528 1.00 111.35 ?  4   THR C C   1 
ATOM   5009 O O   . THR C 3 1   ? 123.011 155.030 149.664 1.00 106.14 ?  4   THR C O   1 
ATOM   5010 C CB  . THR C 3 1   ? 121.375 154.320 147.170 1.00 109.13 ?  4   THR C CB  1 
ATOM   5011 O OG1 . THR C 3 1   ? 120.819 154.070 148.465 1.00 103.47 ?  4   THR C OG1 1 
ATOM   5012 C CG2 . THR C 3 1   ? 121.754 153.000 146.521 1.00 105.62 ?  4   THR C CG2 1 
ATOM   5013 N N   . LEU C 3 2   ? 124.541 154.128 148.283 1.00 97.66  ?  5   LEU C N   1 
ATOM   5014 C CA  . LEU C 3 2   ? 125.401 153.683 149.367 1.00 92.04  ?  5   LEU C CA  1 
ATOM   5015 C C   . LEU C 3 2   ? 126.107 154.865 150.018 1.00 94.68  ?  5   LEU C C   1 
ATOM   5016 O O   . LEU C 3 2   ? 126.360 155.893 149.386 1.00 93.55  ?  5   LEU C O   1 
ATOM   5017 C CB  . LEU C 3 2   ? 126.437 152.686 148.854 1.00 89.70  ?  5   LEU C CB  1 
ATOM   5018 C CG  . LEU C 3 2   ? 125.965 151.626 147.864 1.00 91.50  ?  5   LEU C CG  1 
ATOM   5019 C CD1 . LEU C 3 2   ? 127.156 150.974 147.192 1.00 87.10  ?  5   LEU C CD1 1 
ATOM   5020 C CD2 . LEU C 3 2   ? 125.116 150.591 148.569 1.00 95.22  ?  5   LEU C CD2 1 
ATOM   5021 N N   . SER C 3 3   ? 126.428 154.709 151.299 1.00 86.47  ?  6   SER C N   1 
ATOM   5022 C CA  . SER C 3 3   ? 127.188 155.717 152.016 1.00 86.62  ?  6   SER C CA  1 
ATOM   5023 C C   . SER C 3 3   ? 128.662 155.624 151.632 1.00 89.45  ?  6   SER C C   1 
ATOM   5024 O O   . SER C 3 3   ? 129.076 154.756 150.862 1.00 93.01  ?  6   SER C O   1 
ATOM   5025 C CB  . SER C 3 3   ? 126.993 155.557 153.519 1.00 83.98  ?  6   SER C CB  1 
ATOM   5026 O OG  . SER C 3 3   ? 127.358 154.258 153.939 1.00 91.03  ?  6   SER C OG  1 
ATOM   5027 N N   . ALA C 3 4   ? 129.468 156.543 152.167 1.00 85.18  ?  7   ALA C N   1 
ATOM   5028 C CA  . ALA C 3 4   ? 130.891 156.547 151.847 1.00 83.94  ?  7   ALA C CA  1 
ATOM   5029 C C   . ALA C 3 4   ? 131.566 155.269 152.323 1.00 89.06  ?  7   ALA C C   1 
ATOM   5030 O O   . ALA C 3 4   ? 132.354 154.658 151.589 1.00 91.06  ?  7   ALA C O   1 
ATOM   5031 C CB  . ALA C 3 4   ? 131.562 157.770 152.467 1.00 78.36  ?  7   ALA C CB  1 
ATOM   5032 N N   . GLU C 3 5   ? 131.259 154.843 153.548 1.00 84.12  ?  8   GLU C N   1 
ATOM   5033 C CA  . GLU C 3 5   ? 131.839 153.615 154.073 1.00 77.30  ?  8   GLU C CA  1 
ATOM   5034 C C   . GLU C 3 5   ? 131.335 152.396 153.314 1.00 78.72  ?  8   GLU C C   1 
ATOM   5035 O O   . GLU C 3 5   ? 132.089 151.445 153.094 1.00 91.84  ?  8   GLU C O   1 
ATOM   5036 C CB  . GLU C 3 5   ? 131.531 153.496 155.560 1.00 79.82  ?  8   GLU C CB  1 
ATOM   5037 C CG  . GLU C 3 5   ? 131.915 154.722 156.351 1.00 71.92  ?  8   GLU C CG  1 
ATOM   5038 C CD  . GLU C 3 5   ? 132.435 154.380 157.720 1.00 88.99  ?  8   GLU C CD  1 
ATOM   5039 O OE1 . GLU C 3 5   ? 132.792 153.208 157.942 1.00 96.13  ?  8   GLU C OE1 1 
ATOM   5040 O OE2 . GLU C 3 5   ? 132.485 155.280 158.580 1.00 94.45  -1 8   GLU C OE2 1 
ATOM   5041 N N   . ASP C 3 6   ? 130.065 152.404 152.907 1.00 79.52  ?  9   ASP C N   1 
ATOM   5042 C CA  . ASP C 3 6   ? 129.547 151.314 152.087 1.00 74.42  ?  9   ASP C CA  1 
ATOM   5043 C C   . ASP C 3 6   ? 130.269 151.239 150.750 1.00 83.25  ?  9   ASP C C   1 
ATOM   5044 O O   . ASP C 3 6   ? 130.599 150.147 150.275 1.00 94.35  ?  9   ASP C O   1 
ATOM   5045 C CB  . ASP C 3 6   ? 128.047 151.489 151.868 1.00 83.26  ?  9   ASP C CB  1 
ATOM   5046 C CG  . ASP C 3 6   ? 127.228 151.020 153.045 1.00 100.61 ?  9   ASP C CG  1 
ATOM   5047 O OD1 . ASP C 3 6   ? 127.140 149.794 153.259 1.00 101.07 ?  9   ASP C OD1 1 
ATOM   5048 O OD2 . ASP C 3 6   ? 126.665 151.878 153.755 1.00 106.75 -1 9   ASP C OD2 1 
ATOM   5049 N N   . LYS C 3 7   ? 130.513 152.390 150.123 1.00 82.07  ?  10  LYS C N   1 
ATOM   5050 C CA  . LYS C 3 7   ? 131.238 152.406 148.858 1.00 73.33  ?  10  LYS C CA  1 
ATOM   5051 C C   . LYS C 3 7   ? 132.658 151.890 149.033 1.00 77.79  ?  10  LYS C C   1 
ATOM   5052 O O   . LYS C 3 7   ? 133.163 151.134 148.193 1.00 85.19  ?  10  LYS C O   1 
ATOM   5053 C CB  . LYS C 3 7   ? 131.252 153.819 148.281 1.00 76.81  ?  10  LYS C CB  1 
ATOM   5054 C CG  . LYS C 3 7   ? 129.924 154.269 147.711 1.00 82.00  ?  10  LYS C CG  1 
ATOM   5055 C CD  . LYS C 3 7   ? 130.105 155.448 146.775 1.00 86.18  ?  10  LYS C CD  1 
ATOM   5056 C CE  . LYS C 3 7   ? 129.698 156.749 147.440 1.00 85.87  ?  10  LYS C CE  1 
ATOM   5057 N NZ  . LYS C 3 7   ? 128.240 157.013 147.293 1.00 87.37  1  10  LYS C NZ  1 
ATOM   5058 N N   . ALA C 3 8   ? 133.321 152.285 150.119 1.00 69.11  ?  11  ALA C N   1 
ATOM   5059 C CA  . ALA C 3 8   ? 134.679 151.810 150.358 1.00 59.70  ?  11  ALA C CA  1 
ATOM   5060 C C   . ALA C 3 8   ? 134.702 150.312 150.642 1.00 67.60  ?  11  ALA C C   1 
ATOM   5061 O O   . ALA C 3 8   ? 135.629 149.608 150.223 1.00 75.65  ?  11  ALA C O   1 
ATOM   5062 C CB  . ALA C 3 8   ? 135.306 152.596 151.503 1.00 54.81  ?  11  ALA C CB  1 
ATOM   5063 N N   . ALA C 3 9   ? 133.691 149.804 151.349 1.00 70.37  ?  12  ALA C N   1 
ATOM   5064 C CA  . ALA C 3 9   ? 133.591 148.367 151.574 1.00 51.95  ?  12  ALA C CA  1 
ATOM   5065 C C   . ALA C 3 9   ? 133.364 147.618 150.268 1.00 70.80  ?  12  ALA C C   1 
ATOM   5066 O O   . ALA C 3 9   ? 133.923 146.535 150.064 1.00 86.82  ?  12  ALA C O   1 
ATOM   5067 C CB  . ALA C 3 9   ? 132.470 148.068 152.564 1.00 47.32  ?  12  ALA C CB  1 
ATOM   5068 N N   . VAL C 3 10  ? 132.544 148.174 149.376 1.00 69.49  ?  13  VAL C N   1 
ATOM   5069 C CA  . VAL C 3 10  ? 132.335 147.554 148.070 1.00 60.20  ?  13  VAL C CA  1 
ATOM   5070 C C   . VAL C 3 10  ? 133.634 147.541 147.275 1.00 67.28  ?  13  VAL C C   1 
ATOM   5071 O O   . VAL C 3 10  ? 133.946 146.567 146.581 1.00 77.67  ?  13  VAL C O   1 
ATOM   5072 C CB  . VAL C 3 10  ? 131.210 148.277 147.309 1.00 59.98  ?  13  VAL C CB  1 
ATOM   5073 C CG1 . VAL C 3 10  ? 131.180 147.837 145.864 1.00 62.60  ?  13  VAL C CG1 1 
ATOM   5074 C CG2 . VAL C 3 10  ? 129.876 148.007 147.965 1.00 69.78  ?  13  VAL C CG2 1 
ATOM   5075 N N   . GLU C 3 11  ? 134.410 148.620 147.361 1.00 75.12  ?  14  GLU C N   1 
ATOM   5076 C CA  . GLU C 3 11  ? 135.699 148.655 146.677 1.00 67.98  ?  14  GLU C CA  1 
ATOM   5077 C C   . GLU C 3 11  ? 136.650 147.600 147.230 1.00 74.62  ?  14  GLU C C   1 
ATOM   5078 O O   . GLU C 3 11  ? 137.369 146.937 146.471 1.00 90.71  ?  14  GLU C O   1 
ATOM   5079 C CB  . GLU C 3 11  ? 136.313 150.047 146.793 1.00 69.66  ?  14  GLU C CB  1 
ATOM   5080 C CG  . GLU C 3 11  ? 137.620 150.202 146.047 1.00 88.04  ?  14  GLU C CG  1 
ATOM   5081 C CD  . GLU C 3 11  ? 138.297 151.523 146.327 1.00 93.14  ?  14  GLU C CD  1 
ATOM   5082 O OE1 . GLU C 3 11  ? 137.645 152.411 146.913 1.00 89.58  ?  14  GLU C OE1 1 
ATOM   5083 O OE2 . GLU C 3 11  ? 139.481 151.675 145.963 1.00 91.74  -1 14  GLU C OE2 1 
ATOM   5084 N N   . ARG C 3 12  ? 136.674 147.434 148.554 1.00 70.13  ?  15  ARG C N   1 
ATOM   5085 C CA  . ARG C 3 12  ? 137.508 146.395 149.152 1.00 75.05  ?  15  ARG C CA  1 
ATOM   5086 C C   . ARG C 3 12  ? 137.063 145.010 148.705 1.00 71.23  ?  15  ARG C C   1 
ATOM   5087 O O   . ARG C 3 12  ? 137.895 144.136 148.433 1.00 77.74  ?  15  ARG C O   1 
ATOM   5088 C CB  . ARG C 3 12  ? 137.475 146.504 150.674 1.00 69.72  ?  15  ARG C CB  1 
ATOM   5089 C CG  . ARG C 3 12  ? 137.935 145.250 151.390 1.00 62.39  ?  15  ARG C CG  1 
ATOM   5090 C CD  . ARG C 3 12  ? 137.700 145.350 152.874 1.00 68.98  ?  15  ARG C CD  1 
ATOM   5091 N NE  . ARG C 3 12  ? 138.129 144.149 153.576 1.00 63.71  ?  15  ARG C NE  1 
ATOM   5092 C CZ  . ARG C 3 12  ? 139.344 143.962 154.068 1.00 64.42  ?  15  ARG C CZ  1 
ATOM   5093 N NH1 . ARG C 3 12  ? 140.287 144.879 153.949 1.00 69.80  1  15  ARG C NH1 1 
ATOM   5094 N NH2 . ARG C 3 12  ? 139.619 142.826 154.698 1.00 69.55  ?  15  ARG C NH2 1 
ATOM   5095 N N   . SER C 3 13  ? 135.751 144.789 148.628 1.00 68.21  ?  16  SER C N   1 
ATOM   5096 C CA  . SER C 3 13  ? 135.241 143.511 148.148 1.00 61.39  ?  16  SER C CA  1 
ATOM   5097 C C   . SER C 3 13  ? 135.644 143.265 146.701 1.00 75.61  ?  16  SER C C   1 
ATOM   5098 O O   . SER C 3 13  ? 135.957 142.133 146.322 1.00 79.78  ?  16  SER C O   1 
ATOM   5099 C CB  . SER C 3 13  ? 133.725 143.463 148.299 1.00 65.10  ?  16  SER C CB  1 
ATOM   5100 O OG  . SER C 3 13  ? 133.188 142.347 147.620 1.00 77.95  ?  16  SER C OG  1 
ATOM   5101 N N   . LYS C 3 14  ? 135.632 144.312 145.874 1.00 86.12  ?  17  LYS C N   1 
ATOM   5102 C CA  . LYS C 3 14  ? 136.074 144.173 144.488 1.00 77.99  ?  17  LYS C CA  1 
ATOM   5103 C C   . LYS C 3 14  ? 137.552 143.814 144.410 1.00 78.01  ?  17  LYS C C   1 
ATOM   5104 O O   . LYS C 3 14  ? 137.958 142.994 143.579 1.00 86.30  ?  17  LYS C O   1 
ATOM   5105 C CB  . LYS C 3 14  ? 135.800 145.463 143.720 1.00 76.78  ?  17  LYS C CB  1 
ATOM   5106 C CG  . LYS C 3 14  ? 134.649 145.371 142.746 1.00 83.09  ?  17  LYS C CG  1 
ATOM   5107 C CD  . LYS C 3 14  ? 133.325 145.272 143.473 1.00 91.49  ?  17  LYS C CD  1 
ATOM   5108 C CE  . LYS C 3 14  ? 132.173 145.609 142.548 1.00 94.33  ?  17  LYS C CE  1 
ATOM   5109 N NZ  . LYS C 3 14  ? 132.332 146.963 141.954 1.00 90.40  1  17  LYS C NZ  1 
ATOM   5110 N N   . MET C 3 15  ? 138.375 144.434 145.255 1.00 78.04  ?  18  MET C N   1 
ATOM   5111 C CA  . MET C 3 15  ? 139.793 144.085 145.291 1.00 72.83  ?  18  MET C CA  1 
ATOM   5112 C C   . MET C 3 15  ? 139.988 142.633 145.710 1.00 86.64  ?  18  MET C C   1 
ATOM   5113 O O   . MET C 3 15  ? 140.828 141.916 145.147 1.00 101.31 ?  18  MET C O   1 
ATOM   5114 C CB  . MET C 3 15  ? 140.533 145.022 146.241 1.00 86.49  ?  18  MET C CB  1 
ATOM   5115 C CG  . MET C 3 15  ? 140.964 146.331 145.612 1.00 90.21  ?  18  MET C CG  1 
ATOM   5116 S SD  . MET C 3 15  ? 142.555 146.911 146.222 1.00 116.54 ?  18  MET C SD  1 
ATOM   5117 C CE  . MET C 3 15  ? 143.531 145.420 146.093 1.00 94.25  ?  18  MET C CE  1 
ATOM   5118 N N   . ILE C 3 16  ? 139.215 142.182 146.699 1.00 90.85  ?  19  ILE C N   1 
ATOM   5119 C CA  . ILE C 3 16  ? 139.279 140.788 147.130 1.00 83.01  ?  19  ILE C CA  1 
ATOM   5120 C C   . ILE C 3 16  ? 138.869 139.862 145.994 1.00 78.51  ?  19  ILE C C   1 
ATOM   5121 O O   . ILE C 3 16  ? 139.482 138.811 145.780 1.00 88.88  ?  19  ILE C O   1 
ATOM   5122 C CB  . ILE C 3 16  ? 138.406 140.578 148.381 1.00 80.32  ?  19  ILE C CB  1 
ATOM   5123 C CG1 . ILE C 3 16  ? 139.122 141.100 149.623 1.00 79.09  ?  19  ILE C CG1 1 
ATOM   5124 C CG2 . ILE C 3 16  ? 138.061 139.118 148.561 1.00 80.70  ?  19  ILE C CG2 1 
ATOM   5125 C CD1 . ILE C 3 16  ? 138.284 141.051 150.859 1.00 75.24  ?  19  ILE C CD1 1 
ATOM   5126 N N   . ASP C 3 17  ? 137.826 140.234 145.252 1.00 78.24  ?  20  ASP C N   1 
ATOM   5127 C CA  . ASP C 3 17  ? 137.395 139.440 144.105 1.00 76.22  ?  20  ASP C CA  1 
ATOM   5128 C C   . ASP C 3 17  ? 138.490 139.342 143.054 1.00 81.94  ?  20  ASP C C   1 
ATOM   5129 O O   . ASP C 3 17  ? 138.711 138.274 142.474 1.00 88.88  ?  20  ASP C O   1 
ATOM   5130 C CB  . ASP C 3 17  ? 136.138 140.049 143.489 1.00 81.98  ?  20  ASP C CB  1 
ATOM   5131 C CG  . ASP C 3 17  ? 134.873 139.520 144.109 1.00 93.67  ?  20  ASP C CG  1 
ATOM   5132 O OD1 . ASP C 3 17  ? 134.795 138.298 144.334 1.00 102.41 ?  20  ASP C OD1 1 
ATOM   5133 O OD2 . ASP C 3 17  ? 133.955 140.324 144.370 1.00 90.17  -1 20  ASP C OD2 1 
ATOM   5134 N N   . ARG C 3 18  ? 139.169 140.454 142.778 1.00 91.92  ?  21  ARG C N   1 
ATOM   5135 C CA  . ARG C 3 18  ? 140.251 140.431 141.800 1.00 86.25  ?  21  ARG C CA  1 
ATOM   5136 C C   . ARG C 3 18  ? 141.379 139.515 142.251 1.00 84.92  ?  21  ARG C C   1 
ATOM   5137 O O   . ARG C 3 18  ? 141.922 138.742 141.451 1.00 99.76  ?  21  ARG C O   1 
ATOM   5138 C CB  . ARG C 3 18  ? 140.762 141.849 141.561 1.00 89.12  ?  21  ARG C CB  1 
ATOM   5139 C CG  . ARG C 3 18  ? 142.201 141.938 141.100 1.00 93.20  ?  21  ARG C CG  1 
ATOM   5140 C CD  . ARG C 3 18  ? 142.608 143.386 140.925 1.00 93.33  ?  21  ARG C CD  1 
ATOM   5141 N NE  . ARG C 3 18  ? 141.442 144.237 140.724 1.00 103.34 ?  21  ARG C NE  1 
ATOM   5142 C CZ  . ARG C 3 18  ? 141.251 145.404 141.322 1.00 104.83 ?  21  ARG C CZ  1 
ATOM   5143 N NH1 . ARG C 3 18  ? 142.147 145.908 142.155 1.00 103.06 1  21  ARG C NH1 1 
ATOM   5144 N NH2 . ARG C 3 18  ? 140.132 146.080 141.083 1.00 93.38  ?  21  ARG C NH2 1 
ATOM   5145 N N   . ASN C 3 19  ? 141.741 139.581 143.533 1.00 87.76  ?  22  ASN C N   1 
ATOM   5146 C CA  . ASN C 3 19  ? 142.778 138.690 144.045 1.00 88.71  ?  22  ASN C CA  1 
ATOM   5147 C C   . ASN C 3 19  ? 142.347 137.231 143.959 1.00 95.73  ?  22  ASN C C   1 
ATOM   5148 O O   . ASN C 3 19  ? 143.149 136.357 143.607 1.00 101.78 ?  22  ASN C O   1 
ATOM   5149 C CB  . ASN C 3 19  ? 143.128 139.064 145.481 1.00 95.82  ?  22  ASN C CB  1 
ATOM   5150 C CG  . ASN C 3 19  ? 144.364 139.924 145.567 1.00 101.91 ?  22  ASN C CG  1 
ATOM   5151 O OD1 . ASN C 3 19  ? 144.413 141.016 145.003 1.00 99.92  ?  22  ASN C OD1 1 
ATOM   5152 N ND2 . ASN C 3 19  ? 145.374 139.439 146.277 1.00 100.58 ?  22  ASN C ND2 1 
ATOM   5153 N N   . LEU C 3 20  ? 141.083 136.947 144.280 1.00 88.70  ?  23  LEU C N   1 
ATOM   5154 C CA  . LEU C 3 20  ? 140.579 135.583 144.175 1.00 78.67  ?  23  LEU C CA  1 
ATOM   5155 C C   . LEU C 3 20  ? 140.656 135.083 142.743 1.00 91.03  ?  23  LEU C C   1 
ATOM   5156 O O   . LEU C 3 20  ? 141.050 133.939 142.498 1.00 100.77 ?  23  LEU C O   1 
ATOM   5157 C CB  . LEU C 3 20  ? 139.139 135.507 144.674 1.00 78.92  ?  23  LEU C CB  1 
ATOM   5158 C CG  . LEU C 3 20  ? 138.886 135.661 146.168 1.00 82.66  ?  23  LEU C CG  1 
ATOM   5159 C CD1 . LEU C 3 20  ? 137.399 135.661 146.434 1.00 76.85  ?  23  LEU C CD1 1 
ATOM   5160 C CD2 . LEU C 3 20  ? 139.566 134.556 146.926 1.00 86.59  ?  23  LEU C CD2 1 
ATOM   5161 N N   . ARG C 3 21  ? 140.274 135.927 141.784 1.00 100.79 ?  24  ARG C N   1 
ATOM   5162 C CA  . ARG C 3 21  ? 140.338 135.538 140.381 1.00 97.69  ?  24  ARG C CA  1 
ATOM   5163 C C   . ARG C 3 21  ? 141.772 135.265 139.949 1.00 94.06  ?  24  ARG C C   1 
ATOM   5164 O O   . ARG C 3 21  ? 142.036 134.297 139.230 1.00 101.31 ?  24  ARG C O   1 
ATOM   5165 C CB  . ARG C 3 21  ? 139.715 136.627 139.511 1.00 101.08 ?  24  ARG C CB  1 
ATOM   5166 C CG  . ARG C 3 21  ? 138.721 136.119 138.494 1.00 100.37 ?  24  ARG C CG  1 
ATOM   5167 C CD  . ARG C 3 21  ? 138.096 137.262 137.714 1.00 105.69 ?  24  ARG C CD  1 
ATOM   5168 N NE  . ARG C 3 21  ? 137.687 138.366 138.576 1.00 110.97 ?  24  ARG C NE  1 
ATOM   5169 C CZ  . ARG C 3 21  ? 138.250 139.566 138.576 1.00 109.79 ?  24  ARG C CZ  1 
ATOM   5170 N NH1 . ARG C 3 21  ? 139.267 139.853 137.781 1.00 102.01 1  24  ARG C NH1 1 
ATOM   5171 N NH2 . ARG C 3 21  ? 137.781 140.503 139.395 1.00 104.51 ?  24  ARG C NH2 1 
ATOM   5172 N N   . GLU C 3 22  ? 142.712 136.110 140.374 1.00 93.75  ?  25  GLU C N   1 
ATOM   5173 C CA  . GLU C 3 22  ? 144.106 135.898 139.997 1.00 95.84  ?  25  GLU C CA  1 
ATOM   5174 C C   . GLU C 3 22  ? 144.647 134.596 140.578 1.00 104.59 ?  25  GLU C C   1 
ATOM   5175 O O   . GLU C 3 22  ? 145.320 133.828 139.877 1.00 112.64 ?  25  GLU C O   1 
ATOM   5176 C CB  . GLU C 3 22  ? 144.956 137.088 140.441 1.00 101.06 ?  25  GLU C CB  1 
ATOM   5177 C CG  . GLU C 3 22  ? 146.338 136.720 140.947 1.00 109.20 ?  25  GLU C CG  1 
ATOM   5178 C CD  . GLU C 3 22  ? 146.985 137.840 141.736 1.00 117.92 ?  25  GLU C CD  1 
ATOM   5179 O OE1 . GLU C 3 22  ? 146.969 137.778 142.983 1.00 114.71 ?  25  GLU C OE1 1 
ATOM   5180 O OE2 . GLU C 3 22  ? 147.509 138.784 141.108 1.00 117.03 -1 25  GLU C OE2 1 
ATOM   5181 N N   . ASP C 3 23  ? 144.355 134.319 141.852 1.00 105.25 ?  26  ASP C N   1 
ATOM   5182 C CA  . ASP C 3 23  ? 144.814 133.068 142.451 1.00 103.14 ?  26  ASP C CA  1 
ATOM   5183 C C   . ASP C 3 23  ? 144.147 131.857 141.811 1.00 101.02 ?  26  ASP C C   1 
ATOM   5184 O O   . ASP C 3 23  ? 144.785 130.814 141.640 1.00 104.62 ?  26  ASP C O   1 
ATOM   5185 C CB  . ASP C 3 23  ? 144.582 133.077 143.961 1.00 105.67 ?  26  ASP C CB  1 
ATOM   5186 C CG  . ASP C 3 23  ? 145.492 134.049 144.684 1.00 115.84 ?  26  ASP C CG  1 
ATOM   5187 O OD1 . ASP C 3 23  ? 145.414 135.264 144.420 1.00 118.26 ?  26  ASP C OD1 1 
ATOM   5188 O OD2 . ASP C 3 23  ? 146.292 133.592 145.526 1.00 113.70 -1 26  ASP C OD2 1 
ATOM   5189 N N   . GLY C 3 24  ? 142.870 131.969 141.448 1.00 93.72  ?  27  GLY C N   1 
ATOM   5190 C CA  . GLY C 3 24  ? 142.211 130.863 140.775 1.00 91.58  ?  27  GLY C CA  1 
ATOM   5191 C C   . GLY C 3 24  ? 142.787 130.593 139.400 1.00 98.28  ?  27  GLY C C   1 
ATOM   5192 O O   . GLY C 3 24  ? 142.945 129.436 139.001 1.00 110.48 ?  27  GLY C O   1 
ATOM   5193 N N   . GLU C 3 25  ? 143.104 131.653 138.655 1.00 107.49 ?  28  GLU C N   1 
ATOM   5194 C CA  . GLU C 3 25  ? 143.750 131.482 137.359 1.00 103.38 ?  28  GLU C CA  1 
ATOM   5195 C C   . GLU C 3 25  ? 145.125 130.850 137.513 1.00 101.05 ?  28  GLU C C   1 
ATOM   5196 O O   . GLU C 3 25  ? 145.519 130.000 136.709 1.00 105.02 ?  28  GLU C O   1 
ATOM   5197 C CB  . GLU C 3 25  ? 143.856 132.826 136.643 1.00 103.46 ?  28  GLU C CB  1 
ATOM   5198 C CG  . GLU C 3 25  ? 142.543 133.325 136.069 1.00 110.03 ?  28  GLU C CG  1 
ATOM   5199 C CD  . GLU C 3 25  ? 142.621 134.765 135.606 1.00 115.71 ?  28  GLU C CD  1 
ATOM   5200 O OE1 . GLU C 3 25  ? 143.694 135.384 135.765 1.00 113.66 ?  28  GLU C OE1 1 
ATOM   5201 O OE2 . GLU C 3 25  ? 141.610 135.279 135.085 1.00 113.69 -1 28  GLU C OE2 1 
ATOM   5202 N N   . LYS C 3 26  ? 145.876 131.263 138.535 1.00 102.12 ?  29  LYS C N   1 
ATOM   5203 C CA  . LYS C 3 26  ? 147.178 130.653 138.783 1.00 101.05 ?  29  LYS C CA  1 
ATOM   5204 C C   . LYS C 3 26  ? 147.039 129.178 139.141 1.00 100.36 ?  29  LYS C C   1 
ATOM   5205 O O   . LYS C 3 26  ? 147.837 128.346 138.695 1.00 99.73  ?  29  LYS C O   1 
ATOM   5206 C CB  . LYS C 3 26  ? 147.904 131.412 139.892 1.00 102.35 ?  29  LYS C CB  1 
ATOM   5207 C CG  . LYS C 3 26  ? 148.992 130.617 140.581 1.00 104.81 ?  29  LYS C CG  1 
ATOM   5208 C CD  . LYS C 3 26  ? 150.175 131.498 140.935 1.00 109.99 ?  29  LYS C CD  1 
ATOM   5209 C CE  . LYS C 3 26  ? 151.006 130.885 142.046 1.00 109.60 ?  29  LYS C CE  1 
ATOM   5210 N NZ  . LYS C 3 26  ? 150.807 129.414 142.145 1.00 105.97 1  29  LYS C NZ  1 
ATOM   5211 N N   . ALA C 3 27  ? 146.033 128.835 139.946 1.00 105.51 ?  30  ALA C N   1 
ATOM   5212 C CA  . ALA C 3 27  ? 145.861 127.452 140.375 1.00 100.42 ?  30  ALA C CA  1 
ATOM   5213 C C   . ALA C 3 27  ? 145.388 126.563 139.233 1.00 102.90 ?  30  ALA C C   1 
ATOM   5214 O O   . ALA C 3 27  ? 145.777 125.393 139.152 1.00 111.55 ?  30  ALA C O   1 
ATOM   5215 C CB  . ALA C 3 27  ? 144.880 127.383 141.543 1.00 99.78  ?  30  ALA C CB  1 
ATOM   5216 N N   . ALA C 3 28  ? 144.548 127.093 138.343 1.00 106.28 ?  31  ALA C N   1 
ATOM   5217 C CA  . ALA C 3 28  ? 144.028 126.298 137.237 1.00 105.06 ?  31  ALA C CA  1 
ATOM   5218 C C   . ALA C 3 28  ? 145.098 125.916 136.225 1.00 107.44 ?  31  ALA C C   1 
ATOM   5219 O O   . ALA C 3 28  ? 144.835 125.074 135.361 1.00 109.90 ?  31  ALA C O   1 
ATOM   5220 C CB  . ALA C 3 28  ? 142.901 127.052 136.532 1.00 102.55 ?  31  ALA C CB  1 
ATOM   5221 N N   . ARG C 3 29  ? 146.286 126.508 136.304 1.00 111.90 ?  32  ARG C N   1 
ATOM   5222 C CA  . ARG C 3 29  ? 147.392 126.168 135.424 1.00 109.91 ?  32  ARG C CA  1 
ATOM   5223 C C   . ARG C 3 29  ? 148.274 125.066 135.993 1.00 113.93 ?  32  ARG C C   1 
ATOM   5224 O O   . ARG C 3 29  ? 149.305 124.744 135.395 1.00 114.16 ?  32  ARG C O   1 
ATOM   5225 C CB  . ARG C 3 29  ? 148.237 127.411 135.135 1.00 109.39 ?  32  ARG C CB  1 
ATOM   5226 C CG  . ARG C 3 29  ? 147.526 128.456 134.296 1.00 112.04 ?  32  ARG C CG  1 
ATOM   5227 C CD  . ARG C 3 29  ? 148.470 129.566 133.879 1.00 112.38 ?  32  ARG C CD  1 
ATOM   5228 N NE  . ARG C 3 29  ? 149.434 129.889 134.924 1.00 117.34 ?  32  ARG C NE  1 
ATOM   5229 C CZ  . ARG C 3 29  ? 149.484 131.049 135.562 1.00 119.41 ?  32  ARG C CZ  1 
ATOM   5230 N NH1 . ARG C 3 29  ? 148.635 132.026 135.290 1.00 112.14 1  32  ARG C NH1 1 
ATOM   5231 N NH2 . ARG C 3 29  ? 150.411 131.235 136.497 1.00 117.07 ?  32  ARG C NH2 1 
ATOM   5232 N N   . GLU C 3 30  ? 147.900 124.492 137.129 1.00 113.99 ?  33  GLU C N   1 
ATOM   5233 C CA  . GLU C 3 30  ? 148.666 123.433 137.764 1.00 109.99 ?  33  GLU C CA  1 
ATOM   5234 C C   . GLU C 3 30  ? 148.013 122.083 137.508 1.00 113.46 ?  33  GLU C C   1 
ATOM   5235 O O   . GLU C 3 30  ? 146.794 121.980 137.357 1.00 111.18 ?  33  GLU C O   1 
ATOM   5236 C CB  . GLU C 3 30  ? 148.789 123.669 139.269 1.00 107.11 ?  33  GLU C CB  1 
ATOM   5237 C CG  . GLU C 3 30  ? 150.001 124.478 139.667 1.00 111.58 ?  33  GLU C CG  1 
ATOM   5238 C CD  . GLU C 3 30  ? 149.650 125.650 140.556 1.00 122.18 ?  33  GLU C CD  1 
ATOM   5239 O OE1 . GLU C 3 30  ? 148.796 125.483 141.451 1.00 124.60 ?  33  GLU C OE1 1 
ATOM   5240 O OE2 . GLU C 3 30  ? 150.226 126.741 140.361 1.00 120.20 -1 33  GLU C OE2 1 
ATOM   5241 N N   . VAL C 3 31  ? 148.841 121.047 137.459 1.00 102.88 ?  34  VAL C N   1 
ATOM   5242 C CA  . VAL C 3 31  ? 148.384 119.681 137.249 1.00 93.63  ?  34  VAL C CA  1 
ATOM   5243 C C   . VAL C 3 31  ? 148.369 118.980 138.598 1.00 93.60  ?  34  VAL C C   1 
ATOM   5244 O O   . VAL C 3 31  ? 149.417 118.812 139.231 1.00 97.58  ?  34  VAL C O   1 
ATOM   5245 C CB  . VAL C 3 31  ? 149.280 118.938 136.248 1.00 88.99  ?  34  VAL C CB  1 
ATOM   5246 C CG1 . VAL C 3 31  ? 148.832 117.503 136.108 1.00 96.22  ?  34  VAL C CG1 1 
ATOM   5247 C CG2 . VAL C 3 31  ? 149.257 119.634 134.906 1.00 90.59  ?  34  VAL C CG2 1 
ATOM   5248 N N   . LYS C 3 32  ? 147.186 118.572 139.041 1.00 81.28  ?  35  LYS C N   1 
ATOM   5249 C CA  . LYS C 3 32  ? 147.016 117.909 140.325 1.00 81.94  ?  35  LYS C CA  1 
ATOM   5250 C C   . LYS C 3 32  ? 146.997 116.405 140.102 1.00 82.38  ?  35  LYS C C   1 
ATOM   5251 O O   . LYS C 3 32  ? 146.153 115.895 139.361 1.00 97.18  ?  35  LYS C O   1 
ATOM   5252 C CB  . LYS C 3 32  ? 145.730 118.365 141.010 1.00 91.71  ?  35  LYS C CB  1 
ATOM   5253 C CG  . LYS C 3 32  ? 145.250 119.734 140.585 1.00 90.40  ?  35  LYS C CG  1 
ATOM   5254 C CD  . LYS C 3 32  ? 145.964 120.826 141.354 1.00 95.28  ?  35  LYS C CD  1 
ATOM   5255 C CE  . LYS C 3 32  ? 145.122 122.087 141.420 1.00 95.95  ?  35  LYS C CE  1 
ATOM   5256 N NZ  . LYS C 3 32  ? 144.546 122.438 140.094 1.00 95.05  1  35  LYS C NZ  1 
ATOM   5257 N N   . LEU C 3 33  ? 147.923 115.702 140.744 1.00 71.58  ?  36  LEU C N   1 
ATOM   5258 C CA  . LEU C 3 33  ? 148.036 114.256 140.633 1.00 71.79  ?  36  LEU C CA  1 
ATOM   5259 C C   . LEU C 3 33  ? 147.827 113.635 142.002 1.00 75.74  ?  36  LEU C C   1 
ATOM   5260 O O   . LEU C 3 33  ? 148.393 114.105 142.992 1.00 90.47  ?  36  LEU C O   1 
ATOM   5261 C CB  . LEU C 3 33  ? 149.400 113.849 140.080 1.00 72.53  ?  36  LEU C CB  1 
ATOM   5262 C CG  . LEU C 3 33  ? 149.830 114.487 138.766 1.00 68.74  ?  36  LEU C CG  1 
ATOM   5263 C CD1 . LEU C 3 33  ? 151.321 114.361 138.610 1.00 81.87  ?  36  LEU C CD1 1 
ATOM   5264 C CD2 . LEU C 3 33  ? 149.121 113.822 137.614 1.00 73.14  ?  36  LEU C CD2 1 
ATOM   5265 N N   . LEU C 3 34  ? 147.021 112.584 142.057 1.00 69.07  ?  37  LEU C N   1 
ATOM   5266 C CA  . LEU C 3 34  ? 146.799 111.830 143.281 1.00 64.09  ?  37  LEU C CA  1 
ATOM   5267 C C   . LEU C 3 34  ? 147.679 110.591 143.243 1.00 69.35  ?  37  LEU C C   1 
ATOM   5268 O O   . LEU C 3 34  ? 147.569 109.777 142.322 1.00 87.37  ?  37  LEU C O   1 
ATOM   5269 C CB  . LEU C 3 34  ? 145.326 111.453 143.429 1.00 74.04  ?  37  LEU C CB  1 
ATOM   5270 C CG  . LEU C 3 34  ? 144.946 110.547 144.596 1.00 77.35  ?  37  LEU C CG  1 
ATOM   5271 C CD1 . LEU C 3 34  ? 145.251 111.220 145.914 1.00 74.10  ?  37  LEU C CD1 1 
ATOM   5272 C CD2 . LEU C 3 34  ? 143.479 110.183 144.509 1.00 70.45  ?  37  LEU C CD2 1 
ATOM   5273 N N   . LEU C 3 35  ? 148.552 110.453 144.231 1.00 77.73  ?  38  LEU C N   1 
ATOM   5274 C CA  . LEU C 3 35  ? 149.503 109.354 144.288 1.00 77.57  ?  38  LEU C CA  1 
ATOM   5275 C C   . LEU C 3 35  ? 148.964 108.281 145.224 1.00 83.14  ?  38  LEU C C   1 
ATOM   5276 O O   . LEU C 3 35  ? 148.760 108.535 146.414 1.00 91.46  ?  38  LEU C O   1 
ATOM   5277 C CB  . LEU C 3 35  ? 150.869 109.850 144.754 1.00 75.53  ?  38  LEU C CB  1 
ATOM   5278 C CG  . LEU C 3 35  ? 151.979 108.816 144.914 1.00 85.75  ?  38  LEU C CG  1 
ATOM   5279 C CD1 . LEU C 3 35  ? 152.405 108.274 143.570 1.00 83.56  ?  38  LEU C CD1 1 
ATOM   5280 C CD2 . LEU C 3 35  ? 153.157 109.439 145.628 1.00 91.68  ?  38  LEU C CD2 1 
ATOM   5281 N N   . LEU C 3 36  ? 148.740 107.087 144.685 1.00 87.19  ?  39  LEU C N   1 
ATOM   5282 C CA  . LEU C 3 36  ? 148.164 105.983 145.433 1.00 79.84  ?  39  LEU C CA  1 
ATOM   5283 C C   . LEU C 3 36  ? 149.083 104.775 145.350 1.00 82.92  ?  39  LEU C C   1 
ATOM   5284 O O   . LEU C 3 36  ? 149.902 104.649 144.440 1.00 90.99  ?  39  LEU C O   1 
ATOM   5285 C CB  . LEU C 3 36  ? 146.771 105.617 144.915 1.00 81.95  ?  39  LEU C CB  1 
ATOM   5286 C CG  . LEU C 3 36  ? 145.640 106.551 145.336 1.00 80.74  ?  39  LEU C CG  1 
ATOM   5287 C CD1 . LEU C 3 36  ? 144.447 106.381 144.426 1.00 82.81  ?  39  LEU C CD1 1 
ATOM   5288 C CD2 . LEU C 3 36  ? 145.252 106.292 146.774 1.00 87.62  ?  39  LEU C CD2 1 
ATOM   5289 N N   . GLY C 3 37  ? 148.937 103.887 146.324 1.00 107.92 ?  40  GLY C N   1 
ATOM   5290 C CA  . GLY C 3 37  ? 149.784 102.716 146.392 1.00 109.80 ?  40  GLY C CA  1 
ATOM   5291 C C   . GLY C 3 37  ? 149.496 101.937 147.654 1.00 118.36 ?  40  GLY C C   1 
ATOM   5292 O O   . GLY C 3 37  ? 148.518 102.197 148.356 1.00 124.52 ?  40  GLY C O   1 
ATOM   5293 N N   . ALA C 3 38  ? 150.367 100.971 147.937 1.00 136.75 ?  41  ALA C N   1 
ATOM   5294 C CA  . ALA C 3 38  ? 150.220 100.113 149.106 1.00 136.54 ?  41  ALA C CA  1 
ATOM   5295 C C   . ALA C 3 38  ? 151.411 100.239 150.051 1.00 140.03 ?  41  ALA C C   1 
ATOM   5296 O O   . ALA C 3 38  ? 151.823 99.258  150.673 1.00 136.36 ?  41  ALA C O   1 
ATOM   5297 C CB  . ALA C 3 38  ? 150.019 98.658  148.686 1.00 133.16 ?  41  ALA C CB  1 
ATOM   5298 N N   . GLY C 3 39  ? 151.978 101.437 150.166 1.00 146.56 ?  42  GLY C N   1 
ATOM   5299 C CA  . GLY C 3 39  ? 153.079 101.646 151.084 1.00 144.08 ?  42  GLY C CA  1 
ATOM   5300 C C   . GLY C 3 39  ? 154.427 101.344 150.465 1.00 146.01 ?  42  GLY C C   1 
ATOM   5301 O O   . GLY C 3 39  ? 155.022 102.191 149.794 1.00 143.96 ?  42  GLY C O   1 
ATOM   5302 N N   . GLU C 3 40  ? 154.916 100.125 150.694 1.00 151.26 ?  43  GLU C N   1 
ATOM   5303 C CA  . GLU C 3 40  ? 156.194 99.667  150.163 1.00 151.70 ?  43  GLU C CA  1 
ATOM   5304 C C   . GLU C 3 40  ? 156.179 99.554  148.642 1.00 151.90 ?  43  GLU C C   1 
ATOM   5305 O O   . GLU C 3 40  ? 157.183 99.169  148.035 1.00 149.93 ?  43  GLU C O   1 
ATOM   5306 C CB  . GLU C 3 40  ? 156.557 98.314  150.776 1.00 149.85 ?  43  GLU C CB  1 
ATOM   5307 C CG  . GLU C 3 40  ? 155.867 97.140  150.099 1.00 152.25 ?  43  GLU C CG  1 
ATOM   5308 C CD  . GLU C 3 40  ? 154.398 97.049  150.455 1.00 152.69 ?  43  GLU C CD  1 
ATOM   5309 O OE1 . GLU C 3 40  ? 154.012 97.563  151.525 1.00 151.14 ?  43  GLU C OE1 1 
ATOM   5310 O OE2 . GLU C 3 40  ? 153.628 96.468  149.662 1.00 151.15 -1 43  GLU C OE2 1 
ATOM   5311 N N   . SER C 3 41  ? 155.045 99.886  148.021 1.00 140.34 ?  44  SER C N   1 
ATOM   5312 C CA  . SER C 3 41  ? 154.920 99.794  146.571 1.00 138.18 ?  44  SER C CA  1 
ATOM   5313 C C   . SER C 3 41  ? 155.931 100.668 145.842 1.00 139.78 ?  44  SER C C   1 
ATOM   5314 O O   . SER C 3 41  ? 156.237 100.398 144.677 1.00 139.52 ?  44  SER C O   1 
ATOM   5315 C CB  . SER C 3 41  ? 153.503 100.176 146.150 1.00 135.44 ?  44  SER C CB  1 
ATOM   5316 O OG  . SER C 3 41  ? 153.027 101.271 146.910 1.00 135.03 ?  44  SER C OG  1 
ATOM   5317 N N   . GLY C 3 42  ? 156.451 101.704 146.492 1.00 137.98 ?  45  GLY C N   1 
ATOM   5318 C CA  . GLY C 3 42  ? 157.476 102.527 145.883 1.00 134.63 ?  45  GLY C CA  1 
ATOM   5319 C C   . GLY C 3 42  ? 157.053 103.964 145.673 1.00 138.53 ?  45  GLY C C   1 
ATOM   5320 O O   . GLY C 3 42  ? 157.638 104.672 144.849 1.00 139.30 ?  45  GLY C O   1 
ATOM   5321 N N   . LYS C 3 43  ? 156.036 104.406 146.417 1.00 133.48 ?  46  LYS C N   1 
ATOM   5322 C CA  . LYS C 3 43  ? 155.572 105.783 146.287 1.00 132.33 ?  46  LYS C CA  1 
ATOM   5323 C C   . LYS C 3 43  ? 156.678 106.767 146.639 1.00 135.18 ?  46  LYS C C   1 
ATOM   5324 O O   . LYS C 3 43  ? 156.864 107.777 145.951 1.00 136.06 ?  46  LYS C O   1 
ATOM   5325 C CB  . LYS C 3 43  ? 154.351 106.011 147.176 1.00 128.71 ?  46  LYS C CB  1 
ATOM   5326 C CG  . LYS C 3 43  ? 153.174 105.112 146.861 1.00 129.16 ?  46  LYS C CG  1 
ATOM   5327 C CD  . LYS C 3 43  ? 151.890 105.691 147.420 1.00 130.06 ?  46  LYS C CD  1 
ATOM   5328 C CE  . LYS C 3 43  ? 151.890 105.672 148.936 1.00 130.70 ?  46  LYS C CE  1 
ATOM   5329 N NZ  . LYS C 3 43  ? 151.127 104.514 149.474 1.00 129.90 1  46  LYS C NZ  1 
ATOM   5330 N N   . SER C 3 44  ? 157.425 106.487 147.709 1.00 142.07 ?  47  SER C N   1 
ATOM   5331 C CA  . SER C 3 44  ? 158.562 107.332 148.056 1.00 142.46 ?  47  SER C CA  1 
ATOM   5332 C C   . SER C 3 44  ? 159.628 107.292 146.969 1.00 142.10 ?  47  SER C C   1 
ATOM   5333 O O   . SER C 3 44  ? 160.224 108.322 146.635 1.00 138.44 ?  47  SER C O   1 
ATOM   5334 C CB  . SER C 3 44  ? 159.144 106.897 149.400 1.00 140.24 ?  47  SER C CB  1 
ATOM   5335 O OG  . SER C 3 44  ? 159.791 105.641 149.290 1.00 140.35 ?  47  SER C OG  1 
ATOM   5336 N N   . THR C 3 45  ? 159.884 106.108 146.405 1.00 144.87 ?  48  THR C N   1 
ATOM   5337 C CA  . THR C 3 45  ? 160.884 105.995 145.349 1.00 144.23 ?  48  THR C CA  1 
ATOM   5338 C C   . THR C 3 45  ? 160.438 106.690 144.071 1.00 141.64 ?  48  THR C C   1 
ATOM   5339 O O   . THR C 3 45  ? 161.279 107.183 143.315 1.00 142.17 ?  48  THR C O   1 
ATOM   5340 C CB  . THR C 3 45  ? 161.198 104.526 145.068 1.00 144.93 ?  48  THR C CB  1 
ATOM   5341 O OG1 . THR C 3 45  ? 160.049 103.892 144.493 1.00 146.88 ?  48  THR C OG1 1 
ATOM   5342 C CG2 . THR C 3 45  ? 161.583 103.810 146.353 1.00 139.61 ?  48  THR C CG2 1 
ATOM   5343 N N   . ILE C 3 46  ? 159.132 106.713 143.796 1.00 136.38 ?  49  ILE C N   1 
ATOM   5344 C CA  . ILE C 3 46  ? 158.623 107.493 142.672 1.00 140.56 ?  49  ILE C CA  1 
ATOM   5345 C C   . ILE C 3 46  ? 158.758 108.984 142.955 1.00 141.99 ?  49  ILE C C   1 
ATOM   5346 O O   . ILE C 3 46  ? 159.064 109.778 142.058 1.00 140.64 ?  49  ILE C O   1 
ATOM   5347 C CB  . ILE C 3 46  ? 157.164 107.097 142.366 1.00 137.32 ?  49  ILE C CB  1 
ATOM   5348 C CG1 . ILE C 3 46  ? 157.121 105.973 141.333 1.00 136.69 ?  49  ILE C CG1 1 
ATOM   5349 C CG2 . ILE C 3 46  ? 156.356 108.292 141.877 1.00 133.59 ?  49  ILE C CG2 1 
ATOM   5350 C CD1 . ILE C 3 46  ? 157.417 106.434 139.928 1.00 135.81 ?  49  ILE C CD1 1 
ATOM   5351 N N   . VAL C 3 47  ? 158.535 109.386 144.208 1.00 144.31 ?  50  VAL C N   1 
ATOM   5352 C CA  . VAL C 3 47  ? 158.572 110.800 144.563 1.00 143.30 ?  50  VAL C CA  1 
ATOM   5353 C C   . VAL C 3 47  ? 159.990 111.357 144.478 1.00 144.77 ?  50  VAL C C   1 
ATOM   5354 O O   . VAL C 3 47  ? 160.181 112.532 144.139 1.00 147.06 ?  50  VAL C O   1 
ATOM   5355 C CB  . VAL C 3 47  ? 157.957 110.994 145.963 1.00 141.26 ?  50  VAL C CB  1 
ATOM   5356 C CG1 . VAL C 3 47  ? 158.531 112.217 146.659 1.00 142.15 ?  50  VAL C CG1 1 
ATOM   5357 C CG2 . VAL C 3 47  ? 156.446 111.099 145.863 1.00 140.12 ?  50  VAL C CG2 1 
ATOM   5358 N N   . LYS C 3 48  ? 161.003 110.526 144.743 1.00 147.53 ?  51  LYS C N   1 
ATOM   5359 C CA  . LYS C 3 48  ? 162.358 111.029 144.959 1.00 149.45 ?  51  LYS C CA  1 
ATOM   5360 C C   . LYS C 3 48  ? 162.915 111.792 143.761 1.00 150.11 ?  51  LYS C C   1 
ATOM   5361 O O   . LYS C 3 48  ? 163.837 112.596 143.936 1.00 148.54 ?  51  LYS C O   1 
ATOM   5362 C CB  . LYS C 3 48  ? 163.301 109.879 145.322 1.00 147.33 ?  51  LYS C CB  1 
ATOM   5363 C CG  . LYS C 3 48  ? 164.108 109.327 144.158 1.00 147.16 ?  51  LYS C CG  1 
ATOM   5364 C CD  . LYS C 3 48  ? 164.651 107.942 144.463 1.00 147.65 ?  51  LYS C CD  1 
ATOM   5365 C CE  . LYS C 3 48  ? 165.273 107.311 143.229 1.00 147.46 ?  51  LYS C CE  1 
ATOM   5366 N NZ  . LYS C 3 48  ? 164.287 106.493 142.470 1.00 149.23 1  51  LYS C NZ  1 
ATOM   5367 N N   . GLN C 3 49  ? 162.388 111.574 142.559 1.00 152.39 ?  52  GLN C N   1 
ATOM   5368 C CA  . GLN C 3 49  ? 162.826 112.313 141.383 1.00 151.15 ?  52  GLN C CA  1 
ATOM   5369 C C   . GLN C 3 49  ? 161.858 113.458 141.121 1.00 151.26 ?  52  GLN C C   1 
ATOM   5370 O O   . GLN C 3 49  ? 160.656 113.235 140.938 1.00 145.68 ?  52  GLN C O   1 
ATOM   5371 C CB  . GLN C 3 49  ? 162.933 111.419 140.142 1.00 148.30 ?  52  GLN C CB  1 
ATOM   5372 C CG  . GLN C 3 49  ? 161.774 110.458 139.893 1.00 147.91 ?  52  GLN C CG  1 
ATOM   5373 C CD  . GLN C 3 49  ? 161.791 109.263 140.817 1.00 149.66 ?  52  GLN C CD  1 
ATOM   5374 O OE1 . GLN C 3 49  ? 161.784 109.413 142.035 1.00 153.11 ?  52  GLN C OE1 1 
ATOM   5375 N NE2 . GLN C 3 49  ? 161.815 108.067 140.243 1.00 145.46 ?  52  GLN C NE2 1 
ATOM   5376 N N   . MET C 3 50  ? 162.386 114.677 141.106 1.00 164.09 ?  53  MET C N   1 
ATOM   5377 C CA  . MET C 3 50  ? 161.574 115.861 140.867 1.00 164.10 ?  53  MET C CA  1 
ATOM   5378 C C   . MET C 3 50  ? 162.417 116.970 140.248 1.00 161.35 ?  53  MET C C   1 
ATOM   5379 O O   . MET C 3 50  ? 163.639 116.852 140.153 1.00 159.69 ?  53  MET C O   1 
ATOM   5380 C CB  . MET C 3 50  ? 160.932 116.345 142.169 1.00 162.34 ?  53  MET C CB  1 
ATOM   5381 C CG  . MET C 3 50  ? 161.852 116.310 143.376 1.00 160.77 ?  53  MET C CG  1 
ATOM   5382 S SD  . MET C 3 50  ? 162.847 117.806 143.519 1.00 167.07 ?  53  MET C SD  1 
ATOM   5383 C CE  . MET C 3 50  ? 161.854 118.769 144.656 1.00 158.32 ?  53  MET C CE  1 
ATOM   5384 N N   . THR C 3 179 ? 151.330 114.887 159.372 1.00 116.80 ?  182 THR C N   1 
ATOM   5385 C CA  . THR C 3 179 ? 150.726 113.631 159.801 1.00 120.20 ?  182 THR C CA  1 
ATOM   5386 C C   . THR C 3 179 ? 149.486 113.315 158.972 1.00 121.01 ?  182 THR C C   1 
ATOM   5387 O O   . THR C 3 179 ? 148.920 112.227 159.072 1.00 117.78 ?  182 THR C O   1 
ATOM   5388 C CB  . THR C 3 179 ? 150.345 113.668 161.293 1.00 122.03 ?  182 THR C CB  1 
ATOM   5389 O OG1 . THR C 3 179 ? 149.560 112.515 161.619 1.00 121.26 ?  182 THR C OG1 1 
ATOM   5390 C CG2 . THR C 3 179 ? 149.551 114.922 161.607 1.00 114.51 ?  182 THR C CG2 1 
ATOM   5391 N N   . GLY C 3 180 ? 149.069 114.276 158.153 1.00 104.08 ?  183 GLY C N   1 
ATOM   5392 C CA  . GLY C 3 180 ? 147.899 114.099 157.319 1.00 98.40  ?  183 GLY C CA  1 
ATOM   5393 C C   . GLY C 3 180 ? 148.238 113.871 155.863 1.00 102.40 ?  183 GLY C C   1 
ATOM   5394 O O   . GLY C 3 180 ? 148.788 112.828 155.502 1.00 110.47 ?  183 GLY C O   1 
ATOM   5395 N N   . ILE C 3 181 ? 147.906 114.840 155.016 1.00 92.76  ?  184 ILE C N   1 
ATOM   5396 C CA  . ILE C 3 181 ? 148.218 114.736 153.598 1.00 94.98  ?  184 ILE C CA  1 
ATOM   5397 C C   . ILE C 3 181 ? 149.612 115.294 153.329 1.00 100.71 ?  184 ILE C C   1 
ATOM   5398 O O   . ILE C 3 181 ? 150.155 116.095 154.094 1.00 104.06 ?  184 ILE C O   1 
ATOM   5399 C CB  . ILE C 3 181 ? 147.152 115.451 152.751 1.00 91.70  ?  184 ILE C CB  1 
ATOM   5400 C CG1 . ILE C 3 181 ? 146.932 114.712 151.436 1.00 90.28  ?  184 ILE C CG1 1 
ATOM   5401 C CG2 . ILE C 3 181 ? 147.536 116.896 152.503 1.00 97.22  ?  184 ILE C CG2 1 
ATOM   5402 C CD1 . ILE C 3 181 ? 146.003 115.421 150.509 1.00 89.98  ?  184 ILE C CD1 1 
ATOM   5403 N N   . VAL C 3 182 ? 150.205 114.850 152.224 1.00 96.62  ?  185 VAL C N   1 
ATOM   5404 C CA  . VAL C 3 182 ? 151.533 115.280 151.805 1.00 90.55  ?  185 VAL C CA  1 
ATOM   5405 C C   . VAL C 3 182 ? 151.439 115.813 150.384 1.00 90.38  ?  185 VAL C C   1 
ATOM   5406 O O   . VAL C 3 182 ? 150.863 115.158 149.510 1.00 101.12 ?  185 VAL C O   1 
ATOM   5407 C CB  . VAL C 3 182 ? 152.559 114.135 151.884 1.00 93.24  ?  185 VAL C CB  1 
ATOM   5408 C CG1 . VAL C 3 182 ? 153.915 114.607 151.404 1.00 94.03  ?  185 VAL C CG1 1 
ATOM   5409 C CG2 . VAL C 3 182 ? 152.654 113.606 153.299 1.00 91.50  ?  185 VAL C CG2 1 
ATOM   5410 N N   . GLU C 3 183 ? 152.001 116.995 150.154 1.00 98.88  ?  186 GLU C N   1 
ATOM   5411 C CA  . GLU C 3 183 ? 152.002 117.631 148.845 1.00 95.47  ?  186 GLU C CA  1 
ATOM   5412 C C   . GLU C 3 183 ? 153.435 117.780 148.362 1.00 98.25  ?  186 GLU C C   1 
ATOM   5413 O O   . GLU C 3 183 ? 154.306 118.218 149.119 1.00 107.43 ?  186 GLU C O   1 
ATOM   5414 C CB  . GLU C 3 183 ? 151.319 118.996 148.895 1.00 97.96  ?  186 GLU C CB  1 
ATOM   5415 C CG  . GLU C 3 183 ? 149.872 118.946 149.336 1.00 102.12 ?  186 GLU C CG  1 
ATOM   5416 C CD  . GLU C 3 183 ? 149.135 120.236 149.047 1.00 110.34 ?  186 GLU C CD  1 
ATOM   5417 O OE1 . GLU C 3 183 ? 149.302 120.780 147.936 1.00 106.36 ?  186 GLU C OE1 1 
ATOM   5418 O OE2 . GLU C 3 183 ? 148.393 120.709 149.933 1.00 106.82 -1 186 GLU C OE2 1 
ATOM   5419 N N   . THR C 3 184 ? 153.676 117.412 147.108 1.00 96.01  ?  187 THR C N   1 
ATOM   5420 C CA  . THR C 3 184 ? 154.990 117.527 146.494 1.00 99.95  ?  187 THR C CA  1 
ATOM   5421 C C   . THR C 3 184 ? 154.858 118.325 145.208 1.00 101.20 ?  187 THR C C   1 
ATOM   5422 O O   . THR C 3 184 ? 153.985 118.037 144.385 1.00 109.17 ?  187 THR C O   1 
ATOM   5423 C CB  . THR C 3 184 ? 155.591 116.147 146.210 1.00 102.01 ?  187 THR C CB  1 
ATOM   5424 O OG1 . THR C 3 184 ? 156.019 115.551 147.440 1.00 99.77  ?  187 THR C OG1 1 
ATOM   5425 C CG2 . THR C 3 184 ? 156.777 116.258 145.272 1.00 101.23 ?  187 THR C CG2 1 
ATOM   5426 N N   . HIS C 3 185 ? 155.714 119.328 145.041 1.00 111.39 ?  188 HIS C N   1 
ATOM   5427 C CA  . HIS C 3 185 ? 155.691 120.199 143.876 1.00 112.31 ?  188 HIS C CA  1 
ATOM   5428 C C   . HIS C 3 185 ? 156.945 119.985 143.043 1.00 115.37 ?  188 HIS C C   1 
ATOM   5429 O O   . HIS C 3 185 ? 158.048 119.863 143.584 1.00 118.73 ?  188 HIS C O   1 
ATOM   5430 C CB  . HIS C 3 185 ? 155.594 121.673 144.279 1.00 110.78 ?  188 HIS C CB  1 
ATOM   5431 C CG  . HIS C 3 185 ? 154.386 122.008 145.097 1.00 120.18 ?  188 HIS C CG  1 
ATOM   5432 N ND1 . HIS C 3 185 ? 153.912 123.296 145.223 1.00 121.75 ?  188 HIS C ND1 1 
ATOM   5433 C CD2 . HIS C 3 185 ? 153.554 121.230 145.829 1.00 121.32 ?  188 HIS C CD2 1 
ATOM   5434 C CE1 . HIS C 3 185 ? 152.844 123.297 145.999 1.00 118.99 ?  188 HIS C CE1 1 
ATOM   5435 N NE2 . HIS C 3 185 ? 152.605 122.056 146.380 1.00 121.24 ?  188 HIS C NE2 1 
ATOM   5436 N N   . PHE C 3 186 ? 156.770 119.931 141.727 1.00 112.22 ?  189 PHE C N   1 
ATOM   5437 C CA  . PHE C 3 186 ? 157.897 119.888 140.809 1.00 110.34 ?  189 PHE C CA  1 
ATOM   5438 C C   . PHE C 3 186 ? 157.448 120.445 139.468 1.00 114.37 ?  189 PHE C C   1 
ATOM   5439 O O   . PHE C 3 186 ? 156.255 120.486 139.161 1.00 116.61 ?  189 PHE C O   1 
ATOM   5440 C CB  . PHE C 3 186 ? 158.458 118.471 140.660 1.00 108.88 ?  189 PHE C CB  1 
ATOM   5441 C CG  . PHE C 3 186 ? 157.525 117.510 139.986 1.00 111.96 ?  189 PHE C CG  1 
ATOM   5442 C CD1 . PHE C 3 186 ? 156.526 116.878 140.702 1.00 112.09 ?  189 PHE C CD1 1 
ATOM   5443 C CD2 . PHE C 3 186 ? 157.660 117.220 138.642 1.00 115.95 ?  189 PHE C CD2 1 
ATOM   5444 C CE1 . PHE C 3 186 ? 155.674 115.988 140.088 1.00 110.51 ?  189 PHE C CE1 1 
ATOM   5445 C CE2 . PHE C 3 186 ? 156.810 116.331 138.023 1.00 113.89 ?  189 PHE C CE2 1 
ATOM   5446 C CZ  . PHE C 3 186 ? 155.817 115.713 138.747 1.00 109.33 ?  189 PHE C CZ  1 
ATOM   5447 N N   . THR C 3 187 ? 158.423 120.879 138.675 1.00 121.23 ?  190 THR C N   1 
ATOM   5448 C CA  . THR C 3 187 ? 158.171 121.512 137.390 1.00 119.60 ?  190 THR C CA  1 
ATOM   5449 C C   . THR C 3 187 ? 158.851 120.722 136.284 1.00 114.84 ?  190 THR C C   1 
ATOM   5450 O O   . THR C 3 187 ? 159.984 120.260 136.444 1.00 114.21 ?  190 THR C O   1 
ATOM   5451 C CB  . THR C 3 187 ? 158.672 122.958 137.378 1.00 119.19 ?  190 THR C CB  1 
ATOM   5452 O OG1 . THR C 3 187 ? 158.488 123.537 138.675 1.00 119.03 ?  190 THR C OG1 1 
ATOM   5453 C CG2 . THR C 3 187 ? 157.903 123.777 136.360 1.00 117.97 ?  190 THR C CG2 1 
ATOM   5454 N N   . PHE C 3 188 ? 158.152 120.564 135.163 1.00 107.63 ?  191 PHE C N   1 
ATOM   5455 C CA  . PHE C 3 188 ? 158.689 119.857 134.007 1.00 107.44 ?  191 PHE C CA  1 
ATOM   5456 C C   . PHE C 3 188 ? 158.168 120.519 132.743 1.00 112.52 ?  191 PHE C C   1 
ATOM   5457 O O   . PHE C 3 188 ? 156.959 120.517 132.496 1.00 111.78 ?  191 PHE C O   1 
ATOM   5458 C CB  . PHE C 3 188 ? 158.304 118.377 134.034 1.00 101.80 ?  191 PHE C CB  1 
ATOM   5459 C CG  . PHE C 3 188 ? 159.146 117.522 133.139 1.00 104.12 ?  191 PHE C CG  1 
ATOM   5460 C CD1 . PHE C 3 188 ? 160.447 117.212 133.482 1.00 107.12 ?  191 PHE C CD1 1 
ATOM   5461 C CD2 . PHE C 3 188 ? 158.638 117.031 131.954 1.00 104.82 ?  191 PHE C CD2 1 
ATOM   5462 C CE1 . PHE C 3 188 ? 161.225 116.427 132.660 1.00 107.46 ?  191 PHE C CE1 1 
ATOM   5463 C CE2 . PHE C 3 188 ? 159.411 116.246 131.129 1.00 109.98 ?  191 PHE C CE2 1 
ATOM   5464 C CZ  . PHE C 3 188 ? 160.706 115.944 131.482 1.00 108.58 ?  191 PHE C CZ  1 
ATOM   5465 N N   . LYS C 3 189 ? 159.083 121.080 131.950 1.00 112.17 ?  192 LYS C N   1 
ATOM   5466 C CA  . LYS C 3 189 ? 158.753 121.727 130.680 1.00 108.25 ?  192 LYS C CA  1 
ATOM   5467 C C   . LYS C 3 189 ? 157.700 122.817 130.870 1.00 107.49 ?  192 LYS C C   1 
ATOM   5468 O O   . LYS C 3 189 ? 156.656 122.827 130.216 1.00 106.50 ?  192 LYS C O   1 
ATOM   5469 C CB  . LYS C 3 189 ? 158.299 120.699 129.643 1.00 107.84 ?  192 LYS C CB  1 
ATOM   5470 C CG  . LYS C 3 189 ? 159.285 119.568 129.428 1.00 109.30 ?  192 LYS C CG  1 
ATOM   5471 C CD  . LYS C 3 189 ? 158.742 118.552 128.443 1.00 113.83 ?  192 LYS C CD  1 
ATOM   5472 C CE  . LYS C 3 189 ? 159.459 118.635 127.110 1.00 112.24 ?  192 LYS C CE  1 
ATOM   5473 N NZ  . LYS C 3 189 ? 160.787 117.968 127.169 1.00 110.26 1  192 LYS C NZ  1 
ATOM   5474 N N   . ASP C 3 190 ? 157.985 123.739 131.789 1.00 115.86 ?  193 ASP C N   1 
ATOM   5475 C CA  . ASP C 3 190 ? 157.141 124.897 132.076 1.00 119.95 ?  193 ASP C CA  1 
ATOM   5476 C C   . ASP C 3 190 ? 155.752 124.502 132.562 1.00 122.50 ?  193 ASP C C   1 
ATOM   5477 O O   . ASP C 3 190 ? 154.807 125.290 132.455 1.00 126.00 ?  193 ASP C O   1 
ATOM   5478 C CB  . ASP C 3 190 ? 157.026 125.820 130.857 1.00 121.73 ?  193 ASP C CB  1 
ATOM   5479 C CG  . ASP C 3 190 ? 158.373 126.145 130.242 1.00 125.18 ?  193 ASP C CG  1 
ATOM   5480 O OD1 . ASP C 3 190 ? 159.379 126.160 130.982 1.00 127.87 ?  193 ASP C OD1 1 
ATOM   5481 O OD2 . ASP C 3 190 ? 158.426 126.386 129.018 1.00 121.08 -1 193 ASP C OD2 1 
ATOM   5482 N N   . LEU C 3 191 ? 155.607 123.295 133.099 1.00 107.17 ?  194 LEU C N   1 
ATOM   5483 C CA  . LEU C 3 191 ? 154.344 122.814 133.637 1.00 105.70 ?  194 LEU C CA  1 
ATOM   5484 C C   . LEU C 3 191 ? 154.535 122.490 135.109 1.00 108.85 ?  194 LEU C C   1 
ATOM   5485 O O   . LEU C 3 191 ? 155.472 121.772 135.471 1.00 103.45 ?  194 LEU C O   1 
ATOM   5486 C CB  . LEU C 3 191 ? 153.855 121.582 132.876 1.00 101.87 ?  194 LEU C CB  1 
ATOM   5487 C CG  . LEU C 3 191 ? 152.355 121.303 132.945 1.00 100.59 ?  194 LEU C CG  1 
ATOM   5488 C CD1 . LEU C 3 191 ? 151.573 122.502 132.451 1.00 101.52 ?  194 LEU C CD1 1 
ATOM   5489 C CD2 . LEU C 3 191 ? 152.005 120.064 132.149 1.00 103.46 ?  194 LEU C CD2 1 
ATOM   5490 N N   . HIS C 3 192 ? 153.654 123.018 135.952 1.00 116.28 ?  195 HIS C N   1 
ATOM   5491 C CA  . HIS C 3 192 ? 153.749 122.827 137.392 1.00 116.01 ?  195 HIS C CA  1 
ATOM   5492 C C   . HIS C 3 192 ? 152.877 121.654 137.815 1.00 118.24 ?  195 HIS C C   1 
ATOM   5493 O O   . HIS C 3 192 ? 151.691 121.601 137.477 1.00 116.77 ?  195 HIS C O   1 
ATOM   5494 C CB  . HIS C 3 192 ? 153.335 124.092 138.144 1.00 117.34 ?  195 HIS C CB  1 
ATOM   5495 C CG  . HIS C 3 192 ? 153.909 124.184 139.524 1.00 127.15 ?  195 HIS C CG  1 
ATOM   5496 N ND1 . HIS C 3 192 ? 153.154 124.523 140.625 1.00 125.65 ?  195 HIS C ND1 1 
ATOM   5497 C CD2 . HIS C 3 192 ? 155.167 123.975 139.981 1.00 124.36 ?  195 HIS C CD2 1 
ATOM   5498 C CE1 . HIS C 3 192 ? 153.920 124.520 141.700 1.00 119.24 ?  195 HIS C CE1 1 
ATOM   5499 N NE2 . HIS C 3 192 ? 155.147 124.192 141.337 1.00 122.80 ?  195 HIS C NE2 1 
ATOM   5500 N N   . PHE C 3 193 ? 153.469 120.725 138.557 1.00 105.16 ?  196 PHE C N   1 
ATOM   5501 C CA  . PHE C 3 193 ? 152.789 119.528 139.024 1.00 101.13 ?  196 PHE C CA  1 
ATOM   5502 C C   . PHE C 3 193 ? 152.655 119.562 140.538 1.00 101.85 ?  196 PHE C C   1 
ATOM   5503 O O   . PHE C 3 193 ? 153.597 119.930 141.245 1.00 110.06 ?  196 PHE C O   1 
ATOM   5504 C CB  . PHE C 3 193 ? 153.550 118.268 138.616 1.00 101.09 ?  196 PHE C CB  1 
ATOM   5505 C CG  . PHE C 3 193 ? 153.476 117.952 137.154 1.00 105.32 ?  196 PHE C CG  1 
ATOM   5506 C CD1 . PHE C 3 193 ? 152.379 117.299 136.630 1.00 105.81 ?  196 PHE C CD1 1 
ATOM   5507 C CD2 . PHE C 3 193 ? 154.513 118.291 136.308 1.00 102.11 ?  196 PHE C CD2 1 
ATOM   5508 C CE1 . PHE C 3 193 ? 152.312 117.004 135.289 1.00 104.60 ?  196 PHE C CE1 1 
ATOM   5509 C CE2 . PHE C 3 193 ? 154.451 117.995 134.968 1.00 105.66 ?  196 PHE C CE2 1 
ATOM   5510 C CZ  . PHE C 3 193 ? 153.350 117.352 134.458 1.00 105.31 ?  196 PHE C CZ  1 
ATOM   5511 N N   . LYS C 3 194 ? 151.483 119.177 141.030 1.00 94.52  ?  197 LYS C N   1 
ATOM   5512 C CA  . LYS C 3 194 ? 151.246 118.996 142.456 1.00 91.27  ?  197 LYS C CA  1 
ATOM   5513 C C   . LYS C 3 194 ? 150.821 117.555 142.682 1.00 93.83  ?  197 LYS C C   1 
ATOM   5514 O O   . LYS C 3 194 ? 149.782 117.127 142.171 1.00 106.91 ?  197 LYS C O   1 
ATOM   5515 C CB  . LYS C 3 194 ? 150.178 119.961 142.968 1.00 93.45  ?  197 LYS C CB  1 
ATOM   5516 C CG  . LYS C 3 194 ? 150.466 121.413 142.658 1.00 105.84 ?  197 LYS C CG  1 
ATOM   5517 C CD  . LYS C 3 194 ? 150.284 122.285 143.883 1.00 108.31 ?  197 LYS C CD  1 
ATOM   5518 C CE  . LYS C 3 194 ? 148.875 122.185 144.429 1.00 106.89 ?  197 LYS C CE  1 
ATOM   5519 N NZ  . LYS C 3 194 ? 148.520 123.373 145.252 1.00 103.18 1  197 LYS C NZ  1 
ATOM   5520 N N   . MET C 3 195 ? 151.620 116.811 143.437 1.00 92.48  ?  198 MET C N   1 
ATOM   5521 C CA  . MET C 3 195 ? 151.350 115.411 143.728 1.00 91.65  ?  198 MET C CA  1 
ATOM   5522 C C   . MET C 3 195 ? 150.909 115.285 145.178 1.00 96.39  ?  198 MET C C   1 
ATOM   5523 O O   . MET C 3 195 ? 151.660 115.642 146.089 1.00 107.26 ?  198 MET C O   1 
ATOM   5524 C CB  . MET C 3 195 ? 152.584 114.550 143.468 1.00 92.98  ?  198 MET C CB  1 
ATOM   5525 C CG  . MET C 3 195 ? 152.325 113.064 143.590 1.00 103.00 ?  198 MET C CG  1 
ATOM   5526 S SD  . MET C 3 195 ? 153.551 112.038 142.761 1.00 127.44 ?  198 MET C SD  1 
ATOM   5527 C CE  . MET C 3 195 ? 154.543 113.272 141.937 1.00 103.31 ?  198 MET C CE  1 
ATOM   5528 N N   . PHE C 3 196 ? 149.702 114.769 145.388 1.00 83.18  ?  199 PHE C N   1 
ATOM   5529 C CA  . PHE C 3 196 ? 149.143 114.591 146.722 1.00 80.74  ?  199 PHE C CA  1 
ATOM   5530 C C   . PHE C 3 196 ? 149.252 113.123 147.107 1.00 85.86  ?  199 PHE C C   1 
ATOM   5531 O O   . PHE C 3 196 ? 148.570 112.273 146.532 1.00 96.68  ?  199 PHE C O   1 
ATOM   5532 C CB  . PHE C 3 196 ? 147.691 115.053 146.773 1.00 77.85  ?  199 PHE C CB  1 
ATOM   5533 C CG  . PHE C 3 196 ? 147.457 116.376 146.124 1.00 83.23  ?  199 PHE C CG  1 
ATOM   5534 C CD1 . PHE C 3 196 ? 148.051 117.518 146.622 1.00 84.42  ?  199 PHE C CD1 1 
ATOM   5535 C CD2 . PHE C 3 196 ? 146.638 116.482 145.018 1.00 92.37  ?  199 PHE C CD2 1 
ATOM   5536 C CE1 . PHE C 3 196 ? 147.836 118.736 146.027 1.00 90.02  ?  199 PHE C CE1 1 
ATOM   5537 C CE2 . PHE C 3 196 ? 146.420 117.699 144.421 1.00 91.43  ?  199 PHE C CE2 1 
ATOM   5538 C CZ  . PHE C 3 196 ? 147.020 118.827 144.925 1.00 91.11  ?  199 PHE C CZ  1 
ATOM   5539 N N   . ASP C 3 197 ? 150.101 112.831 148.082 1.00 92.92  ?  200 ASP C N   1 
ATOM   5540 C CA  . ASP C 3 197 ? 150.249 111.484 148.617 1.00 89.83  ?  200 ASP C CA  1 
ATOM   5541 C C   . ASP C 3 197 ? 149.396 111.378 149.873 1.00 94.59  ?  200 ASP C C   1 
ATOM   5542 O O   . ASP C 3 197 ? 149.755 111.921 150.922 1.00 100.81 ?  200 ASP C O   1 
ATOM   5543 C CB  . ASP C 3 197 ? 151.712 111.174 148.919 1.00 92.99  ?  200 ASP C CB  1 
ATOM   5544 C CG  . ASP C 3 197 ? 151.892 109.833 149.590 1.00 104.39 ?  200 ASP C CG  1 
ATOM   5545 O OD1 . ASP C 3 197 ? 151.079 108.924 149.333 1.00 107.86 ?  200 ASP C OD1 1 
ATOM   5546 O OD2 . ASP C 3 197 ? 152.847 109.684 150.378 1.00 104.91 -1 200 ASP C OD2 1 
ATOM   5547 N N   . VAL C 3 198 ? 148.262 110.688 149.765 1.00 101.39 ?  201 VAL C N   1 
ATOM   5548 C CA  . VAL C 3 198 ? 147.387 110.528 150.921 1.00 105.75 ?  201 VAL C CA  1 
ATOM   5549 C C   . VAL C 3 198 ? 148.071 109.684 151.988 1.00 105.19 ?  201 VAL C C   1 
ATOM   5550 O O   . VAL C 3 198 ? 148.114 110.062 153.163 1.00 108.61 ?  201 VAL C O   1 
ATOM   5551 C CB  . VAL C 3 198 ? 146.037 109.932 150.492 1.00 102.90 ?  201 VAL C CB  1 
ATOM   5552 C CG1 . VAL C 3 198 ? 145.114 111.039 150.037 1.00 101.94 ?  201 VAL C CG1 1 
ATOM   5553 C CG2 . VAL C 3 198 ? 146.235 108.922 149.380 1.00 99.46  ?  201 VAL C CG2 1 
ATOM   5554 N N   . GLY C 3 199 ? 148.625 108.540 151.592 1.00 109.52 ?  202 GLY C N   1 
ATOM   5555 C CA  . GLY C 3 199 ? 149.529 107.790 152.442 1.00 114.91 ?  202 GLY C CA  1 
ATOM   5556 C C   . GLY C 3 199 ? 148.989 107.462 153.817 1.00 115.88 ?  202 GLY C C   1 
ATOM   5557 O O   . GLY C 3 199 ? 148.098 106.622 153.963 1.00 115.87 ?  202 GLY C O   1 
ATOM   5558 N N   . ALA C 3 200 ? 149.537 108.124 154.834 1.00 123.27 ?  203 ALA C N   1 
ATOM   5559 C CA  . ALA C 3 200 ? 149.164 107.868 156.219 1.00 125.28 ?  203 ALA C CA  1 
ATOM   5560 C C   . ALA C 3 200 ? 147.829 108.504 156.578 1.00 125.59 ?  203 ALA C C   1 
ATOM   5561 O O   . ALA C 3 200 ? 147.743 109.292 157.525 1.00 123.59 ?  203 ALA C O   1 
ATOM   5562 C CB  . ALA C 3 200 ? 150.258 108.374 157.160 1.00 122.11 ?  203 ALA C CB  1 
ATOM   5563 N N   . GLN C 3 201 ? 146.785 108.170 155.829 1.00 119.53 ?  204 GLN C N   1 
ATOM   5564 C CA  . GLN C 3 201 ? 145.414 108.550 156.146 1.00 115.66 ?  204 GLN C CA  1 
ATOM   5565 C C   . GLN C 3 201 ? 144.672 107.245 156.421 1.00 119.19 ?  204 GLN C C   1 
ATOM   5566 O O   . GLN C 3 201 ? 144.059 106.662 155.526 1.00 118.70 ?  204 GLN C O   1 
ATOM   5567 C CB  . GLN C 3 201 ? 144.774 109.340 155.008 1.00 115.68 ?  204 GLN C CB  1 
ATOM   5568 C CG  . GLN C 3 201 ? 144.687 110.840 155.245 1.00 116.33 ?  204 GLN C CG  1 
ATOM   5569 C CD  . GLN C 3 201 ? 143.706 111.216 156.340 1.00 120.63 ?  204 GLN C CD  1 
ATOM   5570 O OE1 . GLN C 3 201 ? 142.859 110.418 156.738 1.00 119.63 ?  204 GLN C OE1 1 
ATOM   5571 N NE2 . GLN C 3 201 ? 143.817 112.444 156.831 1.00 119.48 ?  204 GLN C NE2 1 
ATOM   5572 N N   . ARG C 3 202 ? 144.739 106.785 157.668 1.00 131.22 ?  205 ARG C N   1 
ATOM   5573 C CA  . ARG C 3 202 ? 144.173 105.490 158.045 1.00 131.90 ?  205 ARG C CA  1 
ATOM   5574 C C   . ARG C 3 202 ? 142.725 105.646 158.510 1.00 132.92 ?  205 ARG C C   1 
ATOM   5575 O O   . ARG C 3 202 ? 142.331 105.216 159.592 1.00 133.60 ?  205 ARG C O   1 
ATOM   5576 C CB  . ARG C 3 202 ? 145.035 104.832 159.116 1.00 131.05 ?  205 ARG C CB  1 
ATOM   5577 C CG  . ARG C 3 202 ? 146.384 104.351 158.611 1.00 131.54 ?  205 ARG C CG  1 
ATOM   5578 C CD  . ARG C 3 202 ? 146.275 103.801 157.200 1.00 133.81 ?  205 ARG C CD  1 
ATOM   5579 N NE  . ARG C 3 202 ? 147.540 103.875 156.480 1.00 137.35 ?  205 ARG C NE  1 
ATOM   5580 C CZ  . ARG C 3 202 ? 147.691 103.561 155.201 1.00 136.27 ?  205 ARG C CZ  1 
ATOM   5581 N NH1 . ARG C 3 202 ? 146.670 103.153 154.464 1.00 132.29 1  205 ARG C NH1 1 
ATOM   5582 N NH2 . ARG C 3 202 ? 148.895 103.660 154.646 1.00 134.11 ?  205 ARG C NH2 1 
ATOM   5583 N N   . SER C 3 203 ? 141.928 106.272 157.655 1.00 121.77 ?  206 SER C N   1 
ATOM   5584 C CA  . SER C 3 203 ? 140.508 106.480 157.893 1.00 116.36 ?  206 SER C CA  1 
ATOM   5585 C C   . SER C 3 203 ? 139.714 105.777 156.796 1.00 117.27 ?  206 SER C C   1 
ATOM   5586 O O   . SER C 3 203 ? 140.271 105.065 155.956 1.00 119.54 ?  206 SER C O   1 
ATOM   5587 C CB  . SER C 3 203 ? 140.187 107.973 157.954 1.00 114.60 ?  206 SER C CB  1 
ATOM   5588 O OG  . SER C 3 203 ? 141.248 108.696 158.551 1.00 119.39 ?  206 SER C OG  1 
ATOM   5589 N N   . GLU C 3 204 ? 138.400 105.976 156.807 1.00 113.28 ?  207 GLU C N   1 
ATOM   5590 C CA  . GLU C 3 204 ? 137.559 105.416 155.759 1.00 117.63 ?  207 GLU C CA  1 
ATOM   5591 C C   . GLU C 3 204 ? 137.804 106.174 154.464 1.00 115.13 ?  207 GLU C C   1 
ATOM   5592 O O   . GLU C 3 204 ? 137.574 107.385 154.391 1.00 113.36 ?  207 GLU C O   1 
ATOM   5593 C CB  . GLU C 3 204 ? 136.088 105.481 156.155 1.00 116.45 ?  207 GLU C CB  1 
ATOM   5594 C CG  . GLU C 3 204 ? 135.190 104.564 155.345 1.00 119.11 ?  207 GLU C CG  1 
ATOM   5595 C CD  . GLU C 3 204 ? 135.898 103.300 154.902 1.00 119.71 ?  207 GLU C CD  1 
ATOM   5596 O OE1 . GLU C 3 204 ? 136.126 102.414 155.753 1.00 116.43 ?  207 GLU C OE1 1 
ATOM   5597 O OE2 . GLU C 3 204 ? 136.227 103.190 153.703 1.00 117.80 -1 207 GLU C OE2 1 
ATOM   5598 N N   . ARG C 3 205 ? 138.272 105.457 153.442 1.00 99.39  ?  208 ARG C N   1 
ATOM   5599 C CA  . ARG C 3 205 ? 138.658 106.103 152.194 1.00 100.86 ?  208 ARG C CA  1 
ATOM   5600 C C   . ARG C 3 205 ? 137.471 106.785 151.531 1.00 99.76  ?  208 ARG C C   1 
ATOM   5601 O O   . ARG C 3 205 ? 137.612 107.868 150.956 1.00 101.50 ?  208 ARG C O   1 
ATOM   5602 C CB  . ARG C 3 205 ? 139.278 105.074 151.253 1.00 104.33 ?  208 ARG C CB  1 
ATOM   5603 C CG  . ARG C 3 205 ? 140.134 105.659 150.152 1.00 101.81 ?  208 ARG C CG  1 
ATOM   5604 C CD  . ARG C 3 205 ? 140.279 104.671 148.999 1.00 103.50 ?  208 ARG C CD  1 
ATOM   5605 N NE  . ARG C 3 205 ? 140.735 103.340 149.398 1.00 108.75 ?  208 ARG C NE  1 
ATOM   5606 C CZ  . ARG C 3 205 ? 141.784 103.072 150.168 1.00 111.90 ?  208 ARG C CZ  1 
ATOM   5607 N NH1 . ARG C 3 205 ? 142.609 104.022 150.580 1.00 103.94 1  208 ARG C NH1 1 
ATOM   5608 N NH2 . ARG C 3 205 ? 142.027 101.811 150.513 1.00 105.97 ?  208 ARG C NH2 1 
ATOM   5609 N N   . LYS C 3 206 ? 136.295 106.163 151.591 1.00 104.31 ?  209 LYS C N   1 
ATOM   5610 C CA  . LYS C 3 206 ? 135.125 106.710 150.920 1.00 107.41 ?  209 LYS C CA  1 
ATOM   5611 C C   . LYS C 3 206 ? 134.615 107.988 151.567 1.00 111.27 ?  209 LYS C C   1 
ATOM   5612 O O   . LYS C 3 206 ? 133.756 108.656 150.983 1.00 109.67 ?  209 LYS C O   1 
ATOM   5613 C CB  . LYS C 3 206 ? 134.010 105.667 150.883 1.00 107.28 ?  209 LYS C CB  1 
ATOM   5614 C CG  . LYS C 3 206 ? 133.145 105.639 152.123 1.00 106.51 ?  209 LYS C CG  1 
ATOM   5615 C CD  . LYS C 3 206 ? 131.750 105.144 151.795 1.00 110.19 ?  209 LYS C CD  1 
ATOM   5616 C CE  . LYS C 3 206 ? 130.784 105.438 152.924 1.00 111.84 ?  209 LYS C CE  1 
ATOM   5617 N NZ  . LYS C 3 206 ? 131.140 104.693 154.162 1.00 111.84 1  209 LYS C NZ  1 
ATOM   5618 N N   . LYS C 3 207 ? 135.109 108.336 152.755 1.00 101.16 ?  210 LYS C N   1 
ATOM   5619 C CA  . LYS C 3 207 ? 134.662 109.556 153.412 1.00 93.60  ?  210 LYS C CA  1 
ATOM   5620 C C   . LYS C 3 207 ? 135.348 110.796 152.856 1.00 97.86  ?  210 LYS C C   1 
ATOM   5621 O O   . LYS C 3 207 ? 134.732 111.865 152.804 1.00 105.86 ?  210 LYS C O   1 
ATOM   5622 C CB  . LYS C 3 207 ? 134.895 109.451 154.917 1.00 91.86  ?  210 LYS C CB  1 
ATOM   5623 C CG  . LYS C 3 207 ? 133.729 108.836 155.661 1.00 93.25  ?  210 LYS C CG  1 
ATOM   5624 C CD  . LYS C 3 207 ? 132.444 109.572 155.343 1.00 100.17 ?  210 LYS C CD  1 
ATOM   5625 C CE  . LYS C 3 207 ? 131.274 108.625 155.209 1.00 101.56 ?  210 LYS C CE  1 
ATOM   5626 N NZ  . LYS C 3 207 ? 130.021 109.357 154.895 1.00 92.99  1  210 LYS C NZ  1 
ATOM   5627 N N   . TRP C 3 208 ? 136.608 110.681 152.437 1.00 97.68  ?  211 TRP C N   1 
ATOM   5628 C CA  . TRP C 3 208 ? 137.356 111.820 151.930 1.00 90.08  ?  211 TRP C CA  1 
ATOM   5629 C C   . TRP C 3 208 ? 137.861 111.638 150.509 1.00 89.50  ?  211 TRP C C   1 
ATOM   5630 O O   . TRP C 3 208 ? 138.576 112.513 150.011 1.00 95.32  ?  211 TRP C O   1 
ATOM   5631 C CB  . TRP C 3 208 ? 138.548 112.128 152.845 1.00 85.42  ?  211 TRP C CB  1 
ATOM   5632 C CG  . TRP C 3 208 ? 139.379 110.937 153.176 1.00 90.65  ?  211 TRP C CG  1 
ATOM   5633 C CD1 . TRP C 3 208 ? 139.337 110.208 154.322 1.00 96.04  ?  211 TRP C CD1 1 
ATOM   5634 C CD2 . TRP C 3 208 ? 140.387 110.337 152.355 1.00 93.82  ?  211 TRP C CD2 1 
ATOM   5635 N NE1 . TRP C 3 208 ? 140.251 109.188 154.269 1.00 99.29  ?  211 TRP C NE1 1 
ATOM   5636 C CE2 . TRP C 3 208 ? 140.909 109.246 153.070 1.00 97.03  ?  211 TRP C CE2 1 
ATOM   5637 C CE3 . TRP C 3 208 ? 140.897 110.615 151.086 1.00 90.07  ?  211 TRP C CE3 1 
ATOM   5638 C CZ2 . TRP C 3 208 ? 141.913 108.433 152.558 1.00 94.17  ?  211 TRP C CZ2 1 
ATOM   5639 C CZ3 . TRP C 3 208 ? 141.890 109.806 150.580 1.00 91.35  ?  211 TRP C CZ3 1 
ATOM   5640 C CH2 . TRP C 3 208 ? 142.389 108.730 151.314 1.00 92.16  ?  211 TRP C CH2 1 
ATOM   5641 N N   . ILE C 3 209 ? 137.528 110.532 149.842 1.00 97.60  ?  212 ILE C N   1 
ATOM   5642 C CA  . ILE C 3 209 ? 138.039 110.316 148.496 1.00 95.04  ?  212 ILE C CA  1 
ATOM   5643 C C   . ILE C 3 209 ? 137.355 111.220 147.484 1.00 96.50  ?  212 ILE C C   1 
ATOM   5644 O O   . ILE C 3 209 ? 137.914 111.471 146.412 1.00 103.13 ?  212 ILE C O   1 
ATOM   5645 C CB  . ILE C 3 209 ? 137.902 108.834 148.100 1.00 97.69  ?  212 ILE C CB  1 
ATOM   5646 C CG1 . ILE C 3 209 ? 138.928 108.474 147.026 1.00 98.52  ?  212 ILE C CG1 1 
ATOM   5647 C CG2 . ILE C 3 209 ? 136.496 108.530 147.621 1.00 94.07  ?  212 ILE C CG2 1 
ATOM   5648 C CD1 . ILE C 3 209 ? 140.359 108.678 147.459 1.00 96.19  ?  212 ILE C CD1 1 
ATOM   5649 N N   . HIS C 3 210 ? 136.161 111.727 147.792 1.00 91.45  ?  213 HIS C N   1 
ATOM   5650 C CA  . HIS C 3 210 ? 135.503 112.662 146.890 1.00 89.43  ?  213 HIS C CA  1 
ATOM   5651 C C   . HIS C 3 210 ? 136.179 114.022 146.869 1.00 95.51  ?  213 HIS C C   1 
ATOM   5652 O O   . HIS C 3 210 ? 135.874 114.830 145.988 1.00 102.36 ?  213 HIS C O   1 
ATOM   5653 C CB  . HIS C 3 210 ? 134.034 112.827 147.273 1.00 97.82  ?  213 HIS C CB  1 
ATOM   5654 C CG  . HIS C 3 210 ? 133.814 113.087 148.730 1.00 96.02  ?  213 HIS C CG  1 
ATOM   5655 N ND1 . HIS C 3 210 ? 134.217 114.250 149.347 1.00 92.84  ?  213 HIS C ND1 1 
ATOM   5656 C CD2 . HIS C 3 210 ? 133.230 112.334 149.690 1.00 95.89  ?  213 HIS C CD2 1 
ATOM   5657 C CE1 . HIS C 3 210 ? 133.894 114.202 150.626 1.00 96.15  ?  213 HIS C CE1 1 
ATOM   5658 N NE2 . HIS C 3 210 ? 133.294 113.050 150.860 1.00 105.79 ?  213 HIS C NE2 1 
ATOM   5659 N N   . CYS C 3 211 ? 137.077 114.295 147.817 1.00 91.55  ?  214 CYS C N   1 
ATOM   5660 C CA  . CYS C 3 211 ? 137.805 115.557 147.806 1.00 86.34  ?  214 CYS C CA  1 
ATOM   5661 C C   . CYS C 3 211 ? 138.675 115.686 146.568 1.00 97.59  ?  214 CYS C C   1 
ATOM   5662 O O   . CYS C 3 211 ? 138.869 116.794 146.058 1.00 105.79 ?  214 CYS C O   1 
ATOM   5663 C CB  . CYS C 3 211 ? 138.663 115.681 149.064 1.00 88.56  ?  214 CYS C CB  1 
ATOM   5664 S SG  . CYS C 3 211 ? 137.741 115.713 150.607 1.00 111.53 ?  214 CYS C SG  1 
ATOM   5665 N N   . PHE C 3 212 ? 139.202 114.573 146.069 1.00 84.34  ?  215 PHE C N   1 
ATOM   5666 C CA  . PHE C 3 212 ? 140.110 114.579 144.934 1.00 77.75  ?  215 PHE C CA  1 
ATOM   5667 C C   . PHE C 3 212 ? 139.405 114.385 143.604 1.00 83.12  ?  215 PHE C C   1 
ATOM   5668 O O   . PHE C 3 212 ? 140.078 114.266 142.579 1.00 93.84  ?  215 PHE C O   1 
ATOM   5669 C CB  . PHE C 3 212 ? 141.175 113.502 145.115 1.00 73.95  ?  215 PHE C CB  1 
ATOM   5670 C CG  . PHE C 3 212 ? 142.001 113.685 146.343 1.00 76.90  ?  215 PHE C CG  1 
ATOM   5671 C CD1 . PHE C 3 212 ? 143.081 114.540 146.341 1.00 77.88  ?  215 PHE C CD1 1 
ATOM   5672 C CD2 . PHE C 3 212 ? 141.687 113.016 147.506 1.00 84.63  ?  215 PHE C CD2 1 
ATOM   5673 C CE1 . PHE C 3 212 ? 143.836 114.714 147.471 1.00 77.38  ?  215 PHE C CE1 1 
ATOM   5674 C CE2 . PHE C 3 212 ? 142.439 113.189 148.637 1.00 84.61  ?  215 PHE C CE2 1 
ATOM   5675 C CZ  . PHE C 3 212 ? 143.513 114.038 148.619 1.00 78.59  ?  215 PHE C CZ  1 
ATOM   5676 N N   . GLU C 3 213 ? 138.076 114.336 143.592 1.00 95.76  ?  216 GLU C N   1 
ATOM   5677 C CA  . GLU C 3 213 ? 137.349 114.293 142.333 1.00 92.02  ?  216 GLU C CA  1 
ATOM   5678 C C   . GLU C 3 213 ? 137.638 115.561 141.548 1.00 101.08 ?  216 GLU C C   1 
ATOM   5679 O O   . GLU C 3 213 ? 137.202 116.650 141.933 1.00 105.38 ?  216 GLU C O   1 
ATOM   5680 C CB  . GLU C 3 213 ? 135.850 114.142 142.574 1.00 93.93  ?  216 GLU C CB  1 
ATOM   5681 C CG  . GLU C 3 213 ? 135.021 114.249 141.312 1.00 98.28  ?  216 GLU C CG  1 
ATOM   5682 C CD  . GLU C 3 213 ? 133.605 114.695 141.586 1.00 106.72 ?  216 GLU C CD  1 
ATOM   5683 O OE1 . GLU C 3 213 ? 133.420 115.601 142.421 1.00 111.77 ?  216 GLU C OE1 1 
ATOM   5684 O OE2 . GLU C 3 213 ? 132.675 114.142 140.964 1.00 108.08 -1 216 GLU C OE2 1 
ATOM   5685 N N   . GLY C 3 214 ? 138.373 115.433 140.450 1.00 92.75  ?  217 GLY C N   1 
ATOM   5686 C CA  . GLY C 3 214 ? 138.825 116.582 139.688 1.00 89.66  ?  217 GLY C CA  1 
ATOM   5687 C C   . GLY C 3 214 ? 140.324 116.663 139.505 1.00 88.51  ?  217 GLY C C   1 
ATOM   5688 O O   . GLY C 3 214 ? 140.793 117.587 138.827 1.00 96.01  ?  217 GLY C O   1 
ATOM   5689 N N   . VAL C 3 215 ? 141.109 115.753 140.081 1.00 78.13  ?  218 VAL C N   1 
ATOM   5690 C CA  . VAL C 3 215 ? 142.534 115.725 139.798 1.00 83.54  ?  218 VAL C CA  1 
ATOM   5691 C C   . VAL C 3 215 ? 142.743 115.342 138.340 1.00 85.88  ?  218 VAL C C   1 
ATOM   5692 O O   . VAL C 3 215 ? 141.906 114.670 137.723 1.00 90.47  ?  218 VAL C O   1 
ATOM   5693 C CB  . VAL C 3 215 ? 143.269 114.752 140.737 1.00 68.84  ?  218 VAL C CB  1 
ATOM   5694 C CG1 . VAL C 3 215 ? 143.340 115.324 142.136 1.00 73.51  ?  218 VAL C CG1 1 
ATOM   5695 C CG2 . VAL C 3 215 ? 142.584 113.403 140.739 1.00 64.10  ?  218 VAL C CG2 1 
ATOM   5696 N N   . THR C 3 216 ? 143.864 115.788 137.775 1.00 76.73  ?  219 THR C N   1 
ATOM   5697 C CA  . THR C 3 216 ? 144.138 115.512 136.370 1.00 70.74  ?  219 THR C CA  1 
ATOM   5698 C C   . THR C 3 216 ? 144.288 114.018 136.124 1.00 77.86  ?  219 THR C C   1 
ATOM   5699 O O   . THR C 3 216 ? 143.718 113.473 135.173 1.00 95.28  ?  219 THR C O   1 
ATOM   5700 C CB  . THR C 3 216 ? 145.392 116.262 135.927 1.00 76.91  ?  219 THR C CB  1 
ATOM   5701 O OG1 . THR C 3 216 ? 145.219 117.661 136.178 1.00 83.06  ?  219 THR C OG1 1 
ATOM   5702 C CG2 . THR C 3 216 ? 145.643 116.053 134.449 1.00 80.26  ?  219 THR C CG2 1 
ATOM   5703 N N   . ALA C 3 217 ? 145.032 113.335 136.984 1.00 63.10  ?  220 ALA C N   1 
ATOM   5704 C CA  . ALA C 3 217 ? 145.264 111.910 136.818 1.00 70.53  ?  220 ALA C CA  1 
ATOM   5705 C C   . ALA C 3 217 ? 145.612 111.316 138.172 1.00 72.68  ?  220 ALA C C   1 
ATOM   5706 O O   . ALA C 3 217 ? 145.926 112.030 139.124 1.00 87.50  ?  220 ALA C O   1 
ATOM   5707 C CB  . ALA C 3 217 ? 146.372 111.641 135.798 1.00 71.73  ?  220 ALA C CB  1 
ATOM   5708 N N   . ILE C 3 218 ? 145.546 109.992 138.244 1.00 66.22  ?  221 ILE C N   1 
ATOM   5709 C CA  . ILE C 3 218 ? 145.899 109.240 139.440 1.00 64.53  ?  221 ILE C CA  1 
ATOM   5710 C C   . ILE C 3 218 ? 147.146 108.432 139.129 1.00 65.17  ?  221 ILE C C   1 
ATOM   5711 O O   . ILE C 3 218 ? 147.182 107.695 138.139 1.00 83.86  ?  221 ILE C O   1 
ATOM   5712 C CB  . ILE C 3 218 ? 144.751 108.321 139.888 1.00 66.81  ?  221 ILE C CB  1 
ATOM   5713 C CG1 . ILE C 3 218 ? 143.532 109.143 140.288 1.00 68.96  ?  221 ILE C CG1 1 
ATOM   5714 C CG2 . ILE C 3 218 ? 145.190 107.445 141.035 1.00 63.50  ?  221 ILE C CG2 1 
ATOM   5715 C CD1 . ILE C 3 218 ? 142.287 108.324 140.429 1.00 72.03  ?  221 ILE C CD1 1 
ATOM   5716 N N   . ILE C 3 219 ? 148.167 108.574 139.960 1.00 67.31  ?  222 ILE C N   1 
ATOM   5717 C CA  . ILE C 3 219 ? 149.389 107.794 139.831 1.00 70.96  ?  222 ILE C CA  1 
ATOM   5718 C C   . ILE C 3 219 ? 149.284 106.630 140.801 1.00 67.83  ?  222 ILE C C   1 
ATOM   5719 O O   . ILE C 3 219 ? 149.323 106.820 142.020 1.00 84.94  ?  222 ILE C O   1 
ATOM   5720 C CB  . ILE C 3 219 ? 150.638 108.638 140.108 1.00 71.72  ?  222 ILE C CB  1 
ATOM   5721 C CG1 . ILE C 3 219 ? 150.699 109.830 139.158 1.00 77.12  ?  222 ILE C CG1 1 
ATOM   5722 C CG2 . ILE C 3 219 ? 151.879 107.793 139.960 1.00 66.20  ?  222 ILE C CG2 1 
ATOM   5723 C CD1 . ILE C 3 219 ? 152.019 110.554 139.189 1.00 73.62  ?  222 ILE C CD1 1 
ATOM   5724 N N   . PHE C 3 220 ? 149.150 105.423 140.271 1.00 71.27  ?  223 PHE C N   1 
ATOM   5725 C CA  . PHE C 3 220 ? 149.048 104.217 141.079 1.00 72.33  ?  223 PHE C CA  1 
ATOM   5726 C C   . PHE C 3 220 ? 150.346 103.437 140.951 1.00 74.66  ?  223 PHE C C   1 
ATOM   5727 O O   . PHE C 3 220 ? 150.729 103.043 139.846 1.00 91.77  ?  223 PHE C O   1 
ATOM   5728 C CB  . PHE C 3 220 ? 147.859 103.365 140.642 1.00 81.19  ?  223 PHE C CB  1 
ATOM   5729 C CG  . PHE C 3 220 ? 147.395 102.400 141.685 1.00 84.36  ?  223 PHE C CG  1 
ATOM   5730 C CD1 . PHE C 3 220 ? 148.077 101.219 141.905 1.00 87.30  ?  223 PHE C CD1 1 
ATOM   5731 C CD2 . PHE C 3 220 ? 146.279 102.673 142.447 1.00 74.55  ?  223 PHE C CD2 1 
ATOM   5732 C CE1 . PHE C 3 220 ? 147.658 100.332 142.862 1.00 83.09  ?  223 PHE C CE1 1 
ATOM   5733 C CE2 . PHE C 3 220 ? 145.855 101.788 143.406 1.00 86.11  ?  223 PHE C CE2 1 
ATOM   5734 C CZ  . PHE C 3 220 ? 146.546 100.616 143.614 1.00 88.31  ?  223 PHE C CZ  1 
ATOM   5735 N N   . CYS C 3 221 ? 151.014 103.211 142.076 1.00 85.77  ?  224 CYS C N   1 
ATOM   5736 C CA  . CYS C 3 221 ? 152.289 102.512 142.105 1.00 92.28  ?  224 CYS C CA  1 
ATOM   5737 C C   . CYS C 3 221 ? 152.101 101.139 142.730 1.00 100.25 ?  224 CYS C C   1 
ATOM   5738 O O   . CYS C 3 221 ? 151.529 101.022 143.817 1.00 113.19 ?  224 CYS C O   1 
ATOM   5739 C CB  . CYS C 3 221 ? 153.335 103.306 142.888 1.00 95.38  ?  224 CYS C CB  1 
ATOM   5740 S SG  . CYS C 3 221 ? 153.550 105.009 142.341 1.00 116.38 ?  224 CYS C SG  1 
ATOM   5741 N N   . VAL C 3 222 ? 152.575 100.106 142.039 1.00 101.30 ?  225 VAL C N   1 
ATOM   5742 C CA  . VAL C 3 222 ? 152.605 98.754  142.575 1.00 100.69 ?  225 VAL C CA  1 
ATOM   5743 C C   . VAL C 3 222 ? 154.024 98.226  142.435 1.00 100.76 ?  225 VAL C C   1 
ATOM   5744 O O   . VAL C 3 222 ? 154.783 98.654  141.559 1.00 107.05 ?  225 VAL C O   1 
ATOM   5745 C CB  . VAL C 3 222 ? 151.591 97.816  141.876 1.00 99.37  ?  225 VAL C CB  1 
ATOM   5746 C CG1 . VAL C 3 222 ? 150.562 98.615  141.100 1.00 98.35  ?  225 VAL C CG1 1 
ATOM   5747 C CG2 . VAL C 3 222 ? 152.293 96.821  140.969 1.00 101.25 ?  225 VAL C CG2 1 
ATOM   5748 N N   . ALA C 3 223 ? 154.392 97.308  143.321 1.00 118.79 ?  226 ALA C N   1 
ATOM   5749 C CA  . ALA C 3 223 ? 155.706 96.682  143.295 1.00 122.92 ?  226 ALA C CA  1 
ATOM   5750 C C   . ALA C 3 223 ? 155.577 95.309  142.653 1.00 123.94 ?  226 ALA C C   1 
ATOM   5751 O O   . ALA C 3 223 ? 154.802 94.471  143.122 1.00 128.55 ?  226 ALA C O   1 
ATOM   5752 C CB  . ALA C 3 223 ? 156.288 96.568  144.702 1.00 125.65 ?  226 ALA C CB  1 
ATOM   5753 N N   . LEU C 3 224 ? 156.335 95.081  141.580 1.00 128.39 ?  227 LEU C N   1 
ATOM   5754 C CA  . LEU C 3 224 ? 156.275 93.798  140.894 1.00 128.80 ?  227 LEU C CA  1 
ATOM   5755 C C   . LEU C 3 224 ? 156.830 92.664  141.741 1.00 132.82 ?  227 LEU C C   1 
ATOM   5756 O O   . LEU C 3 224 ? 156.584 91.496  141.427 1.00 139.64 ?  227 LEU C O   1 
ATOM   5757 C CB  . LEU C 3 224 ? 157.031 93.873  139.570 1.00 128.75 ?  227 LEU C CB  1 
ATOM   5758 C CG  . LEU C 3 224 ? 156.363 94.672  138.454 1.00 129.28 ?  227 LEU C CG  1 
ATOM   5759 C CD1 . LEU C 3 224 ? 157.271 94.742  137.243 1.00 132.03 ?  227 LEU C CD1 1 
ATOM   5760 C CD2 . LEU C 3 224 ? 155.025 94.057  138.089 1.00 129.38 ?  227 LEU C CD2 1 
ATOM   5761 N N   . SER C 3 225 ? 157.562 92.977  142.804 1.00 140.08 ?  228 SER C N   1 
ATOM   5762 C CA  . SER C 3 225 ? 158.128 91.968  143.685 1.00 142.10 ?  228 SER C CA  1 
ATOM   5763 C C   . SER C 3 225 ? 157.190 91.578  144.818 1.00 139.99 ?  228 SER C C   1 
ATOM   5764 O O   . SER C 3 225 ? 157.586 90.796  145.687 1.00 140.47 ?  228 SER C O   1 
ATOM   5765 C CB  . SER C 3 225 ? 159.456 92.463  144.266 1.00 143.32 ?  228 SER C CB  1 
ATOM   5766 O OG  . SER C 3 225 ? 159.345 93.797  144.728 1.00 143.77 ?  228 SER C OG  1 
ATOM   5767 N N   . ASP C 3 226 ? 155.962 92.097  144.830 1.00 145.50 ?  229 ASP C N   1 
ATOM   5768 C CA  . ASP C 3 226 ? 155.019 91.854  145.914 1.00 146.85 ?  229 ASP C CA  1 
ATOM   5769 C C   . ASP C 3 226 ? 154.143 90.631  145.676 1.00 149.75 ?  229 ASP C C   1 
ATOM   5770 O O   . ASP C 3 226 ? 153.016 90.573  146.185 1.00 153.45 ?  229 ASP C O   1 
ATOM   5771 C CB  . ASP C 3 226 ? 154.150 93.090  146.144 1.00 148.06 ?  229 ASP C CB  1 
ATOM   5772 C CG  . ASP C 3 226 ? 154.876 94.175  146.910 1.00 149.66 ?  229 ASP C CG  1 
ATOM   5773 O OD1 . ASP C 3 226 ? 155.980 93.901  147.426 1.00 147.10 ?  229 ASP C OD1 1 
ATOM   5774 O OD2 . ASP C 3 226 ? 154.341 95.299  147.003 1.00 152.78 -1 229 ASP C OD2 1 
ATOM   5775 N N   . TYR C 3 227 ? 154.620 89.657  144.906 1.00 152.58 ?  230 TYR C N   1 
ATOM   5776 C CA  . TYR C 3 227 ? 153.933 88.384  144.750 1.00 154.16 ?  230 TYR C CA  1 
ATOM   5777 C C   . TYR C 3 227 ? 154.555 87.283  145.598 1.00 156.08 ?  230 TYR C C   1 
ATOM   5778 O O   . TYR C 3 227 ? 154.170 86.118  145.464 1.00 154.51 ?  230 TYR C O   1 
ATOM   5779 C CB  . TYR C 3 227 ? 153.910 87.971  143.278 1.00 149.46 ?  230 TYR C CB  1 
ATOM   5780 C CG  . TYR C 3 227 ? 155.226 87.471  142.735 1.00 152.06 ?  230 TYR C CG  1 
ATOM   5781 C CD1 . TYR C 3 227 ? 156.251 88.350  142.425 1.00 151.53 ?  230 TYR C CD1 1 
ATOM   5782 C CD2 . TYR C 3 227 ? 155.435 86.118  142.516 1.00 154.48 ?  230 TYR C CD2 1 
ATOM   5783 C CE1 . TYR C 3 227 ? 157.453 87.895  141.923 1.00 152.75 ?  230 TYR C CE1 1 
ATOM   5784 C CE2 . TYR C 3 227 ? 156.632 85.655  142.015 1.00 153.54 ?  230 TYR C CE2 1 
ATOM   5785 C CZ  . TYR C 3 227 ? 157.637 86.546  141.720 1.00 152.38 ?  230 TYR C CZ  1 
ATOM   5786 O OH  . TYR C 3 227 ? 158.830 86.083  141.219 1.00 152.19 ?  230 TYR C OH  1 
ATOM   5787 N N   . ASP C 3 228 ? 155.514 87.626  146.460 1.00 158.04 ?  231 ASP C N   1 
ATOM   5788 C CA  . ASP C 3 228 ? 156.186 86.620  147.275 1.00 153.63 ?  231 ASP C CA  1 
ATOM   5789 C C   . ASP C 3 228 ? 155.218 85.964  148.253 1.00 157.37 ?  231 ASP C C   1 
ATOM   5790 O O   . ASP C 3 228 ? 154.940 84.763  148.163 1.00 157.73 ?  231 ASP C O   1 
ATOM   5791 C CB  . ASP C 3 228 ? 157.361 87.256  148.022 1.00 155.60 ?  231 ASP C CB  1 
ATOM   5792 C CG  . ASP C 3 228 ? 156.996 88.581  148.669 1.00 158.16 ?  231 ASP C CG  1 
ATOM   5793 O OD1 . ASP C 3 228 ? 155.799 88.937  148.662 1.00 156.76 ?  231 ASP C OD1 1 
ATOM   5794 O OD2 . ASP C 3 228 ? 157.903 89.262  149.191 1.00 157.51 -1 231 ASP C OD2 1 
ATOM   5795 N N   . LEU C 3 229 ? 154.688 86.741  149.189 1.00 161.65 ?  232 LEU C N   1 
ATOM   5796 C CA  . LEU C 3 229 ? 153.859 86.229  150.278 1.00 161.42 ?  232 LEU C CA  1 
ATOM   5797 C C   . LEU C 3 229 ? 153.184 87.421  150.951 1.00 161.11 ?  232 LEU C C   1 
ATOM   5798 O O   . LEU C 3 229 ? 153.243 88.551  150.450 1.00 159.17 ?  232 LEU C O   1 
ATOM   5799 C CB  . LEU C 3 229 ? 154.688 85.408  151.267 1.00 159.24 ?  232 LEU C CB  1 
ATOM   5800 C CG  . LEU C 3 229 ? 154.042 84.147  151.844 1.00 158.77 ?  232 LEU C CG  1 
ATOM   5801 C CD1 . LEU C 3 229 ? 153.473 83.271  150.738 1.00 157.69 ?  232 LEU C CD1 1 
ATOM   5802 C CD2 . LEU C 3 229 ? 155.043 83.372  152.687 1.00 157.82 ?  232 LEU C CD2 1 
ATOM   5803 N N   . VAL C 3 230 ? 152.543 87.161  152.090 1.00 154.67 ?  233 VAL C N   1 
ATOM   5804 C CA  . VAL C 3 230 ? 151.848 88.175  152.882 1.00 154.33 ?  233 VAL C CA  1 
ATOM   5805 C C   . VAL C 3 230 ? 150.755 88.851  152.064 1.00 152.70 ?  233 VAL C C   1 
ATOM   5806 O O   . VAL C 3 230 ? 150.975 89.894  151.452 1.00 152.52 ?  233 VAL C O   1 
ATOM   5807 C CB  . VAL C 3 230 ? 152.831 89.220  153.447 1.00 154.61 ?  233 VAL C CB  1 
ATOM   5808 C CG1 . VAL C 3 230 ? 152.112 90.171  154.396 1.00 151.06 ?  233 VAL C CG1 1 
ATOM   5809 C CG2 . VAL C 3 230 ? 153.989 88.532  154.151 1.00 151.72 ?  233 VAL C CG2 1 
ATOM   5810 N N   . ASN C 3 238 ? 150.404 87.400  147.619 1.00 141.71 ?  241 ASN C N   1 
ATOM   5811 C CA  . ASN C 3 238 ? 149.174 87.856  148.254 1.00 147.10 ?  241 ASN C CA  1 
ATOM   5812 C C   . ASN C 3 238 ? 149.174 89.372  148.413 1.00 148.68 ?  241 ASN C C   1 
ATOM   5813 O O   . ASN C 3 238 ? 148.120 90.004  148.430 1.00 146.30 ?  241 ASN C O   1 
ATOM   5814 C CB  . ASN C 3 238 ? 148.990 87.183  149.615 1.00 149.62 ?  241 ASN C CB  1 
ATOM   5815 C CG  . ASN C 3 238 ? 147.718 87.619  150.315 1.00 148.52 ?  241 ASN C CG  1 
ATOM   5816 O OD1 . ASN C 3 238 ? 147.761 88.265  151.361 1.00 145.64 ?  241 ASN C OD1 1 
ATOM   5817 N ND2 . ASN C 3 238 ? 146.576 87.266  149.738 1.00 145.34 ?  241 ASN C ND2 1 
ATOM   5818 N N   . ARG C 3 239 ? 150.369 89.951  148.542 1.00 147.94 ?  242 ARG C N   1 
ATOM   5819 C CA  . ARG C 3 239 ? 150.477 91.403  148.638 1.00 146.22 ?  242 ARG C CA  1 
ATOM   5820 C C   . ARG C 3 239 ? 150.023 92.068  147.344 1.00 145.19 ?  242 ARG C C   1 
ATOM   5821 O O   . ARG C 3 239 ? 149.330 93.095  147.371 1.00 143.45 ?  242 ARG C O   1 
ATOM   5822 C CB  . ARG C 3 239 ? 151.912 91.791  148.987 1.00 144.46 ?  242 ARG C CB  1 
ATOM   5823 C CG  . ARG C 3 239 ? 152.029 92.910  150.003 1.00 144.15 ?  242 ARG C CG  1 
ATOM   5824 C CD  . ARG C 3 239 ? 153.479 93.316  150.207 1.00 145.51 ?  242 ARG C CD  1 
ATOM   5825 N NE  . ARG C 3 239 ? 154.060 92.672  151.379 1.00 147.64 ?  242 ARG C NE  1 
ATOM   5826 C CZ  . ARG C 3 239 ? 154.870 93.272  152.241 1.00 146.29 ?  242 ARG C CZ  1 
ATOM   5827 N NH1 . ARG C 3 239 ? 155.214 94.540  152.098 1.00 144.12 1  242 ARG C NH1 1 
ATOM   5828 N NH2 . ARG C 3 239 ? 155.347 92.581  153.272 1.00 145.09 ?  242 ARG C NH2 1 
ATOM   5829 N N   . MET C 3 240 ? 150.388 91.490  146.198 1.00 141.77 ?  243 MET C N   1 
ATOM   5830 C CA  . MET C 3 240 ? 149.857 91.999  144.943 1.00 140.27 ?  243 MET C CA  1 
ATOM   5831 C C   . MET C 3 240 ? 148.357 91.781  144.830 1.00 140.14 ?  243 MET C C   1 
ATOM   5832 O O   . MET C 3 240 ? 147.694 92.540  144.126 1.00 142.05 ?  243 MET C O   1 
ATOM   5833 C CB  . MET C 3 240 ? 150.566 91.371  143.743 1.00 138.95 ?  243 MET C CB  1 
ATOM   5834 C CG  . MET C 3 240 ? 150.283 92.123  142.444 1.00 139.79 ?  243 MET C CG  1 
ATOM   5835 S SD  . MET C 3 240 ? 151.597 92.134  141.214 1.00 147.65 ?  243 MET C SD  1 
ATOM   5836 C CE  . MET C 3 240 ? 152.541 90.707  141.704 1.00 143.96 ?  243 MET C CE  1 
ATOM   5837 N N   . HIS C 3 241 ? 147.801 90.778  145.509 1.00 140.04 ?  244 HIS C N   1 
ATOM   5838 C CA  . HIS C 3 241 ? 146.347 90.652  145.537 1.00 141.13 ?  244 HIS C CA  1 
ATOM   5839 C C   . HIS C 3 241 ? 145.710 91.855  146.219 1.00 142.38 ?  244 HIS C C   1 
ATOM   5840 O O   . HIS C 3 241 ? 144.687 92.371  145.756 1.00 140.01 ?  244 HIS C O   1 
ATOM   5841 C CB  . HIS C 3 241 ? 145.942 89.353  146.228 1.00 140.95 ?  244 HIS C CB  1 
ATOM   5842 C CG  . HIS C 3 241 ? 146.074 88.144  145.357 1.00 141.80 ?  244 HIS C CG  1 
ATOM   5843 N ND1 . HIS C 3 241 ? 145.961 88.203  143.986 1.00 141.73 ?  244 HIS C ND1 1 
ATOM   5844 C CD2 . HIS C 3 241 ? 146.317 86.847  145.660 1.00 140.60 ?  244 HIS C CD2 1 
ATOM   5845 C CE1 . HIS C 3 241 ? 146.123 86.994  143.480 1.00 141.25 ?  244 HIS C CE1 1 
ATOM   5846 N NE2 . HIS C 3 241 ? 146.342 86.153  144.475 1.00 141.45 ?  244 HIS C NE2 1 
ATOM   5847 N N   . GLU C 3 242 ? 146.314 92.328  147.311 1.00 139.14 ?  245 GLU C N   1 
ATOM   5848 C CA  . GLU C 3 242 ? 145.855 93.564  147.932 1.00 136.04 ?  245 GLU C CA  1 
ATOM   5849 C C   . GLU C 3 242 ? 146.047 94.750  146.996 1.00 135.33 ?  245 GLU C C   1 
ATOM   5850 O O   . GLU C 3 242 ? 145.213 95.665  146.961 1.00 134.85 ?  245 GLU C O   1 
ATOM   5851 C CB  . GLU C 3 242 ? 146.593 93.793  149.249 1.00 134.03 ?  245 GLU C CB  1 
ATOM   5852 C CG  . GLU C 3 242 ? 146.187 92.839  150.356 1.00 137.80 ?  245 GLU C CG  1 
ATOM   5853 C CD  . GLU C 3 242 ? 144.685 92.684  150.474 1.00 141.93 ?  245 GLU C CD  1 
ATOM   5854 O OE1 . GLU C 3 242 ? 144.019 93.651  150.900 1.00 141.29 ?  245 GLU C OE1 1 
ATOM   5855 O OE2 . GLU C 3 242 ? 144.168 91.597  150.141 1.00 140.57 -1 245 GLU C OE2 1 
ATOM   5856 N N   . SER C 3 243 ? 147.146 94.758  146.236 1.00 124.24 ?  246 SER C N   1 
ATOM   5857 C CA  . SER C 3 243 ? 147.357 95.830  145.267 1.00 119.72 ?  246 SER C CA  1 
ATOM   5858 C C   . SER C 3 243 ? 146.251 95.860  144.219 1.00 122.95 ?  246 SER C C   1 
ATOM   5859 O O   . SER C 3 243 ? 145.734 96.931  143.884 1.00 124.59 ?  246 SER C O   1 
ATOM   5860 C CB  . SER C 3 243 ? 148.720 95.677  144.597 1.00 120.37 ?  246 SER C CB  1 
ATOM   5861 O OG  . SER C 3 243 ? 149.769 95.913  145.517 1.00 118.73 ?  246 SER C OG  1 
ATOM   5862 N N   . MET C 3 244 ? 145.875 94.695  143.686 1.00 119.91 ?  247 MET C N   1 
ATOM   5863 C CA  . MET C 3 244 ? 144.783 94.649  142.715 1.00 117.69 ?  247 MET C CA  1 
ATOM   5864 C C   . MET C 3 244 ? 143.450 95.000  143.358 1.00 122.34 ?  247 MET C C   1 
ATOM   5865 O O   . MET C 3 244 ? 142.589 95.592  142.707 1.00 124.61 ?  247 MET C O   1 
ATOM   5866 C CB  . MET C 3 244 ? 144.691 93.284  142.031 1.00 118.50 ?  247 MET C CB  1 
ATOM   5867 C CG  . MET C 3 244 ? 146.004 92.610  141.732 1.00 122.66 ?  247 MET C CG  1 
ATOM   5868 S SD  . MET C 3 244 ? 145.882 91.429  140.377 1.00 134.50 ?  247 MET C SD  1 
ATOM   5869 C CE  . MET C 3 244 ? 144.185 90.886  140.552 1.00 124.48 ?  247 MET C CE  1 
ATOM   5870 N N   . LYS C 3 245 ? 143.249 94.636  144.626 1.00 119.03 ?  248 LYS C N   1 
ATOM   5871 C CA  . LYS C 3 245 ? 142.027 95.052  145.307 1.00 117.68 ?  248 LYS C CA  1 
ATOM   5872 C C   . LYS C 3 245 ? 141.937 96.570  145.392 1.00 118.80 ?  248 LYS C C   1 
ATOM   5873 O O   . LYS C 3 245 ? 140.888 97.159  145.101 1.00 116.55 ?  248 LYS C O   1 
ATOM   5874 C CB  . LYS C 3 245 ? 141.962 94.437  146.703 1.00 119.80 ?  248 LYS C CB  1 
ATOM   5875 C CG  . LYS C 3 245 ? 141.213 93.121  146.770 1.00 121.71 ?  248 LYS C CG  1 
ATOM   5876 C CD  . LYS C 3 245 ? 140.905 92.740  148.207 1.00 120.50 ?  248 LYS C CD  1 
ATOM   5877 C CE  . LYS C 3 245 ? 140.325 91.337  148.293 1.00 119.76 ?  248 LYS C CE  1 
ATOM   5878 N NZ  . LYS C 3 245 ? 140.261 90.678  146.960 1.00 119.95 1  248 LYS C NZ  1 
ATOM   5879 N N   . LEU C 3 246 ? 143.036 97.221  145.778 1.00 109.61 ?  249 LEU C N   1 
ATOM   5880 C CA  . LEU C 3 246 ? 143.045 98.678  145.855 1.00 107.14 ?  249 LEU C CA  1 
ATOM   5881 C C   . LEU C 3 246 ? 142.870 99.306  144.478 1.00 109.93 ?  249 LEU C C   1 
ATOM   5882 O O   . LEU C 3 246 ? 142.149 100.300 144.329 1.00 108.40 ?  249 LEU C O   1 
ATOM   5883 C CB  . LEU C 3 246 ? 144.339 99.161  146.506 1.00 100.22 ?  249 LEU C CB  1 
ATOM   5884 C CG  . LEU C 3 246 ? 144.436 100.664 146.771 1.00 105.28 ?  249 LEU C CG  1 
ATOM   5885 C CD1 . LEU C 3 246 ? 143.141 101.199 147.350 1.00 110.11 ?  249 LEU C CD1 1 
ATOM   5886 C CD2 . LEU C 3 246 ? 145.600 100.963 147.694 1.00 105.57 ?  249 LEU C CD2 1 
ATOM   5887 N N   . PHE C 3 247 ? 143.526 98.744  143.461 1.00 100.11 ?  250 PHE C N   1 
ATOM   5888 C CA  . PHE C 3 247 ? 143.381 99.265  142.107 1.00 99.35  ?  250 PHE C CA  1 
ATOM   5889 C C   . PHE C 3 247 ? 141.949 99.121  141.615 1.00 100.57 ?  250 PHE C C   1 
ATOM   5890 O O   . PHE C 3 247 ? 141.423 100.016 140.950 1.00 105.43 ?  250 PHE C O   1 
ATOM   5891 C CB  . PHE C 3 247 ? 144.344 98.552  141.159 1.00 98.97  ?  250 PHE C CB  1 
ATOM   5892 C CG  . PHE C 3 247 ? 144.396 99.156  139.786 1.00 98.91  ?  250 PHE C CG  1 
ATOM   5893 C CD1 . PHE C 3 247 ? 143.539 98.725  138.791 1.00 106.10 ?  250 PHE C CD1 1 
ATOM   5894 C CD2 . PHE C 3 247 ? 145.301 100.155 139.491 1.00 93.09  ?  250 PHE C CD2 1 
ATOM   5895 C CE1 . PHE C 3 247 ? 143.584 99.281  137.534 1.00 101.81 ?  250 PHE C CE1 1 
ATOM   5896 C CE2 . PHE C 3 247 ? 145.350 100.711 138.236 1.00 97.69  ?  250 PHE C CE2 1 
ATOM   5897 C CZ  . PHE C 3 247 ? 144.491 100.273 137.257 1.00 101.65 ?  250 PHE C CZ  1 
ATOM   5898 N N   . ASP C 3 248 ? 141.309 97.991  141.916 1.00 111.55 ?  251 ASP C N   1 
ATOM   5899 C CA  . ASP C 3 248 ? 139.922 97.790  141.523 1.00 112.15 ?  251 ASP C CA  1 
ATOM   5900 C C   . ASP C 3 248 ? 139.004 98.774  142.229 1.00 115.25 ?  251 ASP C C   1 
ATOM   5901 O O   . ASP C 3 248 ? 138.072 99.311  141.621 1.00 118.95 ?  251 ASP C O   1 
ATOM   5902 C CB  . ASP C 3 248 ? 139.504 96.353  141.824 1.00 111.93 ?  251 ASP C CB  1 
ATOM   5903 C CG  . ASP C 3 248 ? 138.250 95.948  141.089 1.00 117.88 ?  251 ASP C CG  1 
ATOM   5904 O OD1 . ASP C 3 248 ? 137.824 96.694  140.185 1.00 119.06 ?  251 ASP C OD1 1 
ATOM   5905 O OD2 . ASP C 3 248 ? 137.689 94.881  141.415 1.00 119.94 -1 251 ASP C OD2 1 
ATOM   5906 N N   . SER C 3 249 ? 139.244 99.015  143.519 1.00 111.48 ?  252 SER C N   1 
ATOM   5907 C CA  . SER C 3 249 ? 138.411 99.965  144.248 1.00 111.83 ?  252 SER C CA  1 
ATOM   5908 C C   . SER C 3 249 ? 138.577 101.381 143.709 1.00 110.20 ?  252 SER C C   1 
ATOM   5909 O O   . SER C 3 249 ? 137.592 102.110 143.556 1.00 108.83 ?  252 SER C O   1 
ATOM   5910 C CB  . SER C 3 249 ? 138.741 99.916  145.738 1.00 112.40 ?  252 SER C CB  1 
ATOM   5911 O OG  . SER C 3 249 ? 138.589 101.193 146.331 1.00 116.56 ?  252 SER C OG  1 
ATOM   5912 N N   . ILE C 3 250 ? 139.814 101.788 143.419 1.00 104.47 ?  253 ILE C N   1 
ATOM   5913 C CA  . ILE C 3 250 ? 140.066 103.159 142.981 1.00 105.11 ?  253 ILE C CA  1 
ATOM   5914 C C   . ILE C 3 250 ? 139.594 103.367 141.547 1.00 102.78 ?  253 ILE C C   1 
ATOM   5915 O O   . ILE C 3 250 ? 138.938 104.365 141.232 1.00 108.23 ?  253 ILE C O   1 
ATOM   5916 C CB  . ILE C 3 250 ? 141.557 103.501 143.137 1.00 105.72 ?  253 ILE C CB  1 
ATOM   5917 C CG1 . ILE C 3 250 ? 141.898 103.722 144.610 1.00 106.49 ?  253 ILE C CG1 1 
ATOM   5918 C CG2 . ILE C 3 250 ? 141.913 104.722 142.313 1.00 104.56 ?  253 ILE C CG2 1 
ATOM   5919 C CD1 . ILE C 3 250 ? 141.063 104.787 145.271 1.00 106.71 ?  253 ILE C CD1 1 
ATOM   5920 N N   . CYS C 3 251 ? 139.931 102.435 140.655 1.00 108.77 ?  254 CYS C N   1 
ATOM   5921 C CA  . CYS C 3 251 ? 139.602 102.591 139.243 1.00 111.27 ?  254 CYS C CA  1 
ATOM   5922 C C   . CYS C 3 251 ? 138.096 102.626 139.029 1.00 114.10 ?  254 CYS C C   1 
ATOM   5923 O O   . CYS C 3 251 ? 137.577 103.485 138.308 1.00 115.37 ?  254 CYS C O   1 
ATOM   5924 C CB  . CYS C 3 251 ? 140.233 101.454 138.439 1.00 109.48 ?  254 CYS C CB  1 
ATOM   5925 S SG  . CYS C 3 251 ? 140.270 101.716 136.660 1.00 128.96 ?  254 CYS C SG  1 
ATOM   5926 N N   . ASN C 3 252 ? 137.378 101.699 139.650 1.00 114.97 ?  255 ASN C N   1 
ATOM   5927 C CA  . ASN C 3 252 ? 135.927 101.612 139.510 1.00 113.25 ?  255 ASN C CA  1 
ATOM   5928 C C   . ASN C 3 252 ? 135.236 102.353 140.651 1.00 113.28 ?  255 ASN C C   1 
ATOM   5929 O O   . ASN C 3 252 ? 134.438 101.802 141.406 1.00 115.97 ?  255 ASN C O   1 
ATOM   5930 C CB  . ASN C 3 252 ? 135.498 100.152 139.451 1.00 114.10 ?  255 ASN C CB  1 
ATOM   5931 C CG  . ASN C 3 252 ? 136.245 99.376  138.392 1.00 113.37 ?  255 ASN C CG  1 
ATOM   5932 O OD1 . ASN C 3 252 ? 136.218 99.730  137.216 1.00 114.65 ?  255 ASN C OD1 1 
ATOM   5933 N ND2 . ASN C 3 252 ? 136.928 98.319  138.805 1.00 114.47 ?  255 ASN C ND2 1 
ATOM   5934 N N   . ASN C 3 253 ? 135.563 103.635 140.762 1.00 105.05 ?  256 ASN C N   1 
ATOM   5935 C CA  . ASN C 3 253 ? 134.992 104.519 141.764 1.00 106.31 ?  256 ASN C CA  1 
ATOM   5936 C C   . ASN C 3 253 ? 134.094 105.534 141.075 1.00 108.92 ?  256 ASN C C   1 
ATOM   5937 O O   . ASN C 3 253 ? 134.409 106.009 139.981 1.00 110.20 ?  256 ASN C O   1 
ATOM   5938 C CB  . ASN C 3 253 ? 136.091 105.233 142.552 1.00 104.00 ?  256 ASN C CB  1 
ATOM   5939 C CG  . ASN C 3 253 ? 135.717 105.459 143.996 1.00 104.27 ?  256 ASN C CG  1 
ATOM   5940 O OD1 . ASN C 3 253 ? 134.541 105.534 144.338 1.00 112.08 ?  256 ASN C OD1 1 
ATOM   5941 N ND2 . ASN C 3 253 ? 136.719 105.558 144.857 1.00 103.60 ?  256 ASN C ND2 1 
ATOM   5942 N N   . LYS C 3 254 ? 132.967 105.856 141.712 1.00 100.06 ?  257 LYS C N   1 
ATOM   5943 C CA  . LYS C 3 254 ? 132.026 106.784 141.095 1.00 100.07 ?  257 LYS C CA  1 
ATOM   5944 C C   . LYS C 3 254 ? 132.626 108.174 140.943 1.00 101.01 ?  257 LYS C C   1 
ATOM   5945 O O   . LYS C 3 254 ? 132.244 108.917 140.033 1.00 96.81  ?  257 LYS C O   1 
ATOM   5946 C CB  . LYS C 3 254 ? 130.734 106.847 141.908 1.00 98.13  ?  257 LYS C CB  1 
ATOM   5947 C CG  . LYS C 3 254 ? 130.932 107.052 143.395 1.00 99.89  ?  257 LYS C CG  1 
ATOM   5948 C CD  . LYS C 3 254 ? 129.754 107.803 143.990 1.00 99.32  ?  257 LYS C CD  1 
ATOM   5949 C CE  . LYS C 3 254 ? 129.680 107.616 145.493 1.00 99.70  ?  257 LYS C CE  1 
ATOM   5950 N NZ  . LYS C 3 254 ? 128.275 107.628 145.978 1.00 100.94 1  257 LYS C NZ  1 
ATOM   5951 N N   . TRP C 3 255 ? 133.553 108.547 141.823 1.00 97.37  ?  258 TRP C N   1 
ATOM   5952 C CA  . TRP C 3 255 ? 134.200 109.848 141.710 1.00 96.72  ?  258 TRP C CA  1 
ATOM   5953 C C   . TRP C 3 255 ? 135.230 109.872 140.589 1.00 103.11 ?  258 TRP C C   1 
ATOM   5954 O O   . TRP C 3 255 ? 135.305 110.848 139.835 1.00 103.21 ?  258 TRP C O   1 
ATOM   5955 C CB  . TRP C 3 255 ? 134.838 110.223 143.046 1.00 92.34  ?  258 TRP C CB  1 
ATOM   5956 C CG  . TRP C 3 255 ? 133.868 110.148 144.176 1.00 94.38  ?  258 TRP C CG  1 
ATOM   5957 C CD1 . TRP C 3 255 ? 133.931 109.322 145.255 1.00 96.09  ?  258 TRP C CD1 1 
ATOM   5958 C CD2 . TRP C 3 255 ? 132.677 110.923 144.332 1.00 95.42  ?  258 TRP C CD2 1 
ATOM   5959 N NE1 . TRP C 3 255 ? 132.855 109.537 146.078 1.00 93.38  ?  258 TRP C NE1 1 
ATOM   5960 C CE2 . TRP C 3 255 ? 132.070 110.516 145.532 1.00 97.90  ?  258 TRP C CE2 1 
ATOM   5961 C CE3 . TRP C 3 255 ? 132.065 111.924 143.574 1.00 88.79  ?  258 TRP C CE3 1 
ATOM   5962 C CZ2 . TRP C 3 255 ? 130.884 111.074 145.992 1.00 101.28 ?  258 TRP C CZ2 1 
ATOM   5963 C CZ3 . TRP C 3 255 ? 130.890 112.474 144.031 1.00 87.84  ?  258 TRP C CZ3 1 
ATOM   5964 C CH2 . TRP C 3 255 ? 130.311 112.050 145.228 1.00 98.15  ?  258 TRP C CH2 1 
ATOM   5965 N N   . PHE C 3 256 ? 136.023 108.816 140.459 1.00 100.23 ?  259 PHE C N   1 
ATOM   5966 C CA  . PHE C 3 256 ? 137.041 108.730 139.414 1.00 95.73  ?  259 PHE C CA  1 
ATOM   5967 C C   . PHE C 3 256 ? 136.496 107.988 138.197 1.00 102.51 ?  259 PHE C C   1 
ATOM   5968 O O   . PHE C 3 256 ? 137.034 106.979 137.749 1.00 109.74 ?  259 PHE C O   1 
ATOM   5969 C CB  . PHE C 3 256 ? 138.295 108.058 139.957 1.00 89.61  ?  259 PHE C CB  1 
ATOM   5970 C CG  . PHE C 3 256 ? 138.783 108.649 141.241 1.00 95.73  ?  259 PHE C CG  1 
ATOM   5971 C CD1 . PHE C 3 256 ? 138.927 110.015 141.376 1.00 94.05  ?  259 PHE C CD1 1 
ATOM   5972 C CD2 . PHE C 3 256 ? 139.097 107.840 142.314 1.00 102.83 ?  259 PHE C CD2 1 
ATOM   5973 C CE1 . PHE C 3 256 ? 139.376 110.560 142.553 1.00 89.28  ?  259 PHE C CE1 1 
ATOM   5974 C CE2 . PHE C 3 256 ? 139.545 108.382 143.494 1.00 101.35 ?  259 PHE C CE2 1 
ATOM   5975 C CZ  . PHE C 3 256 ? 139.684 109.744 143.613 1.00 96.35  ?  259 PHE C CZ  1 
ATOM   5976 N N   . THR C 3 257 ? 135.396 108.515 137.660 1.00 113.84 ?  260 THR C N   1 
ATOM   5977 C CA  . THR C 3 257 ? 134.774 107.891 136.498 1.00 114.59 ?  260 THR C CA  1 
ATOM   5978 C C   . THR C 3 257 ? 135.582 108.150 135.234 1.00 116.02 ?  260 THR C C   1 
ATOM   5979 O O   . THR C 3 257 ? 135.763 107.247 134.409 1.00 116.84 ?  260 THR C O   1 
ATOM   5980 C CB  . THR C 3 257 ? 133.339 108.396 136.340 1.00 116.95 ?  260 THR C CB  1 
ATOM   5981 O OG1 . THR C 3 257 ? 132.483 107.694 137.248 1.00 118.06 ?  260 THR C OG1 1 
ATOM   5982 C CG2 . THR C 3 257 ? 132.839 108.180 134.923 1.00 116.70 ?  260 THR C CG2 1 
ATOM   5983 N N   . ASP C 3 258 ? 136.096 109.369 135.073 1.00 118.59 ?  261 ASP C N   1 
ATOM   5984 C CA  . ASP C 3 258 ? 136.782 109.763 133.849 1.00 119.63 ?  261 ASP C CA  1 
ATOM   5985 C C   . ASP C 3 258 ? 138.202 110.256 134.087 1.00 119.27 ?  261 ASP C C   1 
ATOM   5986 O O   . ASP C 3 258 ? 138.807 110.818 133.167 1.00 118.26 ?  261 ASP C O   1 
ATOM   5987 C CB  . ASP C 3 258 ? 135.976 110.840 133.122 1.00 119.80 ?  261 ASP C CB  1 
ATOM   5988 C CG  . ASP C 3 258 ? 135.290 111.791 134.077 1.00 123.18 ?  261 ASP C CG  1 
ATOM   5989 O OD1 . ASP C 3 258 ? 135.615 111.758 135.282 1.00 120.41 ?  261 ASP C OD1 1 
ATOM   5990 O OD2 . ASP C 3 258 ? 134.424 112.569 133.625 1.00 121.16 -1 261 ASP C OD2 1 
ATOM   5991 N N   . THR C 3 259 ? 138.753 110.071 135.282 1.00 102.28 ?  262 THR C N   1 
ATOM   5992 C CA  . THR C 3 259 ? 140.123 110.479 135.562 1.00 99.33  ?  262 THR C CA  1 
ATOM   5993 C C   . THR C 3 259 ? 141.060 109.335 135.202 1.00 95.80  ?  262 THR C C   1 
ATOM   5994 O O   . THR C 3 259 ? 140.965 108.245 135.774 1.00 98.69  ?  262 THR C O   1 
ATOM   5995 C CB  . THR C 3 259 ? 140.301 110.873 137.026 1.00 92.23  ?  262 THR C CB  1 
ATOM   5996 O OG1 . THR C 3 259 ? 140.733 109.735 137.777 1.00 98.61  ?  262 THR C OG1 1 
ATOM   5997 C CG2 . THR C 3 259 ? 138.998 111.388 137.600 1.00 96.92  ?  262 THR C CG2 1 
ATOM   5998 N N   . SER C 3 260 ? 141.961 109.584 134.259 1.00 83.22  ?  263 SER C N   1 
ATOM   5999 C CA  . SER C 3 260 ? 142.873 108.551 133.799 1.00 79.83  ?  263 SER C CA  1 
ATOM   6000 C C   . SER C 3 260 ? 143.839 108.155 134.905 1.00 77.18  ?  263 SER C C   1 
ATOM   6001 O O   . SER C 3 260 ? 144.149 108.940 135.802 1.00 86.89  ?  263 SER C O   1 
ATOM   6002 C CB  . SER C 3 260 ? 143.646 109.031 132.576 1.00 89.32  ?  263 SER C CB  1 
ATOM   6003 O OG  . SER C 3 260 ? 142.767 109.556 131.598 1.00 97.13  ?  263 SER C OG  1 
ATOM   6004 N N   . ILE C 3 261 ? 144.313 106.917 134.836 1.00 67.16  ?  264 ILE C N   1 
ATOM   6005 C CA  . ILE C 3 261 ? 145.202 106.349 135.839 1.00 65.58  ?  264 ILE C CA  1 
ATOM   6006 C C   . ILE C 3 261 ? 146.542 106.062 135.184 1.00 71.31  ?  264 ILE C C   1 
ATOM   6007 O O   . ILE C 3 261 ? 146.603 105.362 134.169 1.00 85.00  ?  264 ILE C O   1 
ATOM   6008 C CB  . ILE C 3 261 ? 144.613 105.071 136.458 1.00 66.96  ?  264 ILE C CB  1 
ATOM   6009 C CG1 . ILE C 3 261 ? 143.256 105.370 137.092 1.00 71.34  ?  264 ILE C CG1 1 
ATOM   6010 C CG2 . ILE C 3 261 ? 145.573 104.481 137.470 1.00 69.06  ?  264 ILE C CG2 1 
ATOM   6011 C CD1 . ILE C 3 261 ? 142.844 104.384 138.147 1.00 74.88  ?  264 ILE C CD1 1 
ATOM   6012 N N   . ILE C 3 262 ? 147.607 106.604 135.758 1.00 71.72  ?  265 ILE C N   1 
ATOM   6013 C CA  . ILE C 3 262 ? 148.967 106.321 135.323 1.00 64.58  ?  265 ILE C CA  1 
ATOM   6014 C C   . ILE C 3 262 ? 149.511 105.241 136.243 1.00 67.30  ?  265 ILE C C   1 
ATOM   6015 O O   . ILE C 3 262 ? 149.824 105.506 137.406 1.00 84.55  ?  265 ILE C O   1 
ATOM   6016 C CB  . ILE C 3 262 ? 149.845 107.578 135.355 1.00 62.79  ?  265 ILE C CB  1 
ATOM   6017 C CG1 . ILE C 3 262 ? 149.252 108.662 134.459 1.00 63.16  ?  265 ILE C CG1 1 
ATOM   6018 C CG2 . ILE C 3 262 ? 151.257 107.248 134.924 1.00 67.93  ?  265 ILE C CG2 1 
ATOM   6019 C CD1 . ILE C 3 262 ? 149.626 110.056 134.869 1.00 69.29  ?  265 ILE C CD1 1 
ATOM   6020 N N   . LEU C 3 263 ? 149.624 104.022 135.733 1.00 77.05  ?  266 LEU C N   1 
ATOM   6021 C CA  . LEU C 3 263 ? 150.041 102.887 136.541 1.00 77.07  ?  266 LEU C CA  1 
ATOM   6022 C C   . LEU C 3 263 ? 151.550 102.709 136.453 1.00 73.81  ?  266 LEU C C   1 
ATOM   6023 O O   . LEU C 3 263 ? 152.109 102.625 135.357 1.00 89.66  ?  266 LEU C O   1 
ATOM   6024 C CB  . LEU C 3 263 ? 149.326 101.617 136.082 1.00 79.65  ?  266 LEU C CB  1 
ATOM   6025 C CG  . LEU C 3 263 ? 149.581 100.337 136.874 1.00 83.93  ?  266 LEU C CG  1 
ATOM   6026 C CD1 . LEU C 3 263 ? 148.961 100.430 138.248 1.00 87.26  ?  266 LEU C CD1 1 
ATOM   6027 C CD2 . LEU C 3 263 ? 149.036 99.142  136.125 1.00 82.74  ?  266 LEU C CD2 1 
ATOM   6028 N N   . PHE C 3 264 ? 152.203 102.656 137.606 1.00 78.26  ?  267 PHE C N   1 
ATOM   6029 C CA  . PHE C 3 264 ? 153.641 102.454 137.695 1.00 85.63  ?  267 PHE C CA  1 
ATOM   6030 C C   . PHE C 3 264 ? 153.909 101.093 138.314 1.00 94.41  ?  267 PHE C C   1 
ATOM   6031 O O   . PHE C 3 264 ? 153.371 100.778 139.379 1.00 110.66 ?  267 PHE C O   1 
ATOM   6032 C CB  . PHE C 3 264 ? 154.299 103.549 138.533 1.00 87.30  ?  267 PHE C CB  1 
ATOM   6033 C CG  . PHE C 3 264 ? 154.644 104.780 137.756 1.00 90.16  ?  267 PHE C CG  1 
ATOM   6034 C CD1 . PHE C 3 264 ? 155.353 104.695 136.577 1.00 97.42  ?  267 PHE C CD1 1 
ATOM   6035 C CD2 . PHE C 3 264 ? 154.253 106.023 138.203 1.00 91.53  ?  267 PHE C CD2 1 
ATOM   6036 C CE1 . PHE C 3 264 ? 155.668 105.827 135.862 1.00 95.90  ?  267 PHE C CE1 1 
ATOM   6037 C CE2 . PHE C 3 264 ? 154.565 107.157 137.491 1.00 94.01  ?  267 PHE C CE2 1 
ATOM   6038 C CZ  . PHE C 3 264 ? 155.273 107.059 136.321 1.00 92.98  ?  267 PHE C CZ  1 
ATOM   6039 N N   . LEU C 3 265 ? 154.735 100.292 137.654 1.00 97.13  ?  268 LEU C N   1 
ATOM   6040 C CA  . LEU C 3 265 ? 155.095 98.963  138.137 1.00 98.18  ?  268 LEU C CA  1 
ATOM   6041 C C   . LEU C 3 265 ? 156.559 99.013  138.563 1.00 99.81  ?  268 LEU C C   1 
ATOM   6042 O O   . LEU C 3 265 ? 157.465 98.769  137.767 1.00 111.17 ?  268 LEU C O   1 
ATOM   6043 C CB  . LEU C 3 265 ? 154.837 97.906  137.071 1.00 101.70 ?  268 LEU C CB  1 
ATOM   6044 C CG  . LEU C 3 265 ? 153.437 97.952  136.451 1.00 107.03 ?  268 LEU C CG  1 
ATOM   6045 C CD1 . LEU C 3 265 ? 153.251 96.858  135.426 1.00 106.71 ?  268 LEU C CD1 1 
ATOM   6046 C CD2 . LEU C 3 265 ? 152.368 97.845  137.519 1.00 104.08 ?  268 LEU C CD2 1 
ATOM   6047 N N   . ASN C 3 266 ? 156.780 99.329  139.835 1.00 113.72 ?  269 ASN C N   1 
ATOM   6048 C CA  . ASN C 3 266 ? 158.120 99.510  140.363 1.00 116.34 ?  269 ASN C CA  1 
ATOM   6049 C C   . ASN C 3 266 ? 158.832 98.167  140.507 1.00 117.85 ?  269 ASN C C   1 
ATOM   6050 O O   . ASN C 3 266 ? 158.242 97.095  140.351 1.00 122.67 ?  269 ASN C O   1 
ATOM   6051 C CB  . ASN C 3 266 ? 158.067 100.211 141.720 1.00 119.29 ?  269 ASN C CB  1 
ATOM   6052 C CG  . ASN C 3 266 ? 157.256 101.491 141.688 1.00 122.78 ?  269 ASN C CG  1 
ATOM   6053 O OD1 . ASN C 3 266 ? 156.167 101.566 142.248 1.00 119.75 ?  269 ASN C OD1 1 
ATOM   6054 N ND2 . ASN C 3 266 ? 157.791 102.511 141.030 1.00 124.07 ?  269 ASN C ND2 1 
ATOM   6055 N N   . LYS C 3 267 ? 160.128 98.245  140.812 1.00 135.51 ?  270 LYS C N   1 
ATOM   6056 C CA  . LYS C 3 267 ? 160.943 97.083  141.172 1.00 137.88 ?  270 LYS C CA  1 
ATOM   6057 C C   . LYS C 3 267 ? 160.937 96.019  140.075 1.00 137.86 ?  270 LYS C C   1 
ATOM   6058 O O   . LYS C 3 267 ? 160.619 94.853  140.312 1.00 141.89 ?  270 LYS C O   1 
ATOM   6059 C CB  . LYS C 3 267 ? 160.484 96.488  142.506 1.00 137.31 ?  270 LYS C CB  1 
ATOM   6060 C CG  . LYS C 3 267 ? 160.153 97.516  143.573 1.00 136.64 ?  270 LYS C CG  1 
ATOM   6061 C CD  . LYS C 3 267 ? 161.407 98.057  144.234 1.00 136.61 ?  270 LYS C CD  1 
ATOM   6062 C CE  . LYS C 3 267 ? 161.251 98.104  145.745 1.00 136.78 ?  270 LYS C CE  1 
ATOM   6063 N NZ  . LYS C 3 267 ? 159.824 98.222  146.153 1.00 136.62 1  270 LYS C NZ  1 
ATOM   6064 N N   . LYS C 3 268 ? 161.305 96.426  138.860 1.00 140.97 ?  271 LYS C N   1 
ATOM   6065 C CA  . LYS C 3 268 ? 161.376 95.459  137.770 1.00 143.83 ?  271 LYS C CA  1 
ATOM   6066 C C   . LYS C 3 268 ? 162.610 94.569  137.886 1.00 147.85 ?  271 LYS C C   1 
ATOM   6067 O O   . LYS C 3 268 ? 162.560 93.393  137.506 1.00 149.19 ?  271 LYS C O   1 
ATOM   6068 C CB  . LYS C 3 268 ? 161.337 96.179  136.420 1.00 143.82 ?  271 LYS C CB  1 
ATOM   6069 C CG  . LYS C 3 268 ? 162.679 96.661  135.900 1.00 145.67 ?  271 LYS C CG  1 
ATOM   6070 C CD  . LYS C 3 268 ? 162.519 97.918  135.066 1.00 145.76 ?  271 LYS C CD  1 
ATOM   6071 C CE  . LYS C 3 268 ? 162.437 97.593  133.586 1.00 144.96 ?  271 LYS C CE  1 
ATOM   6072 N NZ  . LYS C 3 268 ? 162.308 98.823  132.758 1.00 143.83 1  271 LYS C NZ  1 
ATOM   6073 N N   . ASP C 3 269 ? 163.717 95.097  138.416 1.00 152.56 ?  272 ASP C N   1 
ATOM   6074 C CA  . ASP C 3 269 ? 164.905 94.272  138.611 1.00 152.26 ?  272 ASP C CA  1 
ATOM   6075 C C   . ASP C 3 269 ? 164.689 93.243  139.715 1.00 152.60 ?  272 ASP C C   1 
ATOM   6076 O O   . ASP C 3 269 ? 165.105 92.084  139.585 1.00 151.97 ?  272 ASP C O   1 
ATOM   6077 C CB  . ASP C 3 269 ? 166.115 95.157  138.909 1.00 151.56 ?  272 ASP C CB  1 
ATOM   6078 C CG  . ASP C 3 269 ? 166.032 95.825  140.265 1.00 155.18 ?  272 ASP C CG  1 
ATOM   6079 O OD1 . ASP C 3 269 ? 165.199 96.741  140.425 1.00 154.13 ?  272 ASP C OD1 1 
ATOM   6080 O OD2 . ASP C 3 269 ? 166.800 95.434  141.170 1.00 155.16 -1 272 ASP C OD2 1 
ATOM   6081 N N   . LEU C 3 270 ? 164.033 93.644  140.807 1.00 148.51 ?  273 LEU C N   1 
ATOM   6082 C CA  . LEU C 3 270 ? 163.655 92.677  141.831 1.00 149.15 ?  273 LEU C CA  1 
ATOM   6083 C C   . LEU C 3 270 ? 162.690 91.645  141.269 1.00 149.89 ?  273 LEU C C   1 
ATOM   6084 O O   . LEU C 3 270 ? 162.746 90.466  141.638 1.00 151.98 ?  273 LEU C O   1 
ATOM   6085 C CB  . LEU C 3 270 ? 163.038 93.388  143.033 1.00 149.12 ?  273 LEU C CB  1 
ATOM   6086 C CG  . LEU C 3 270 ? 163.998 93.851  144.128 1.00 148.33 ?  273 LEU C CG  1 
ATOM   6087 C CD1 . LEU C 3 270 ? 164.939 92.720  144.516 1.00 147.41 ?  273 LEU C CD1 1 
ATOM   6088 C CD2 . LEU C 3 270 ? 164.776 95.084  143.698 1.00 149.12 ?  273 LEU C CD2 1 
ATOM   6089 N N   . PHE C 3 271 ? 161.793 92.070  140.378 1.00 146.18 ?  274 PHE C N   1 
ATOM   6090 C CA  . PHE C 3 271 ? 160.894 91.124  139.731 1.00 144.49 ?  274 PHE C CA  1 
ATOM   6091 C C   . PHE C 3 271 ? 161.670 90.101  138.915 1.00 147.91 ?  274 PHE C C   1 
ATOM   6092 O O   . PHE C 3 271 ? 161.372 88.903  138.966 1.00 150.19 ?  274 PHE C O   1 
ATOM   6093 C CB  . PHE C 3 271 ? 159.900 91.866  138.842 1.00 145.05 ?  274 PHE C CB  1 
ATOM   6094 C CG  . PHE C 3 271 ? 158.845 90.983  138.252 1.00 146.11 ?  274 PHE C CG  1 
ATOM   6095 C CD1 . PHE C 3 271 ? 158.139 90.103  139.051 1.00 145.78 ?  274 PHE C CD1 1 
ATOM   6096 C CD2 . PHE C 3 271 ? 158.564 91.026  136.900 1.00 147.77 ?  274 PHE C CD2 1 
ATOM   6097 C CE1 . PHE C 3 271 ? 157.165 89.287  138.513 1.00 147.17 ?  274 PHE C CE1 1 
ATOM   6098 C CE2 . PHE C 3 271 ? 157.593 90.211  136.356 1.00 147.15 ?  274 PHE C CE2 1 
ATOM   6099 C CZ  . PHE C 3 271 ? 156.893 89.340  137.165 1.00 147.00 ?  274 PHE C CZ  1 
ATOM   6100 N N   . GLU C 3 272 ? 162.670 90.556  138.156 1.00 153.62 ?  275 GLU C N   1 
ATOM   6101 C CA  . GLU C 3 272 ? 163.497 89.633  137.386 1.00 154.79 ?  275 GLU C CA  1 
ATOM   6102 C C   . GLU C 3 272 ? 164.219 88.654  138.302 1.00 156.22 ?  275 GLU C C   1 
ATOM   6103 O O   . GLU C 3 272 ? 164.253 87.444  138.042 1.00 156.06 ?  275 GLU C O   1 
ATOM   6104 C CB  . GLU C 3 272 ? 164.506 90.416  136.547 1.00 155.43 ?  275 GLU C CB  1 
ATOM   6105 C CG  . GLU C 3 272 ? 163.919 91.124  135.342 1.00 157.06 ?  275 GLU C CG  1 
ATOM   6106 C CD  . GLU C 3 272 ? 164.592 90.717  134.046 1.00 158.91 ?  275 GLU C CD  1 
ATOM   6107 O OE1 . GLU C 3 272 ? 165.138 89.595  133.985 1.00 158.63 ?  275 GLU C OE1 1 
ATOM   6108 O OE2 . GLU C 3 272 ? 164.583 91.522  133.092 1.00 157.89 -1 275 GLU C OE2 1 
ATOM   6109 N N   . GLU C 3 273 ? 164.799 89.167  139.390 1.00 161.93 ?  276 GLU C N   1 
ATOM   6110 C CA  . GLU C 3 273 ? 165.541 88.309  140.308 1.00 162.09 ?  276 GLU C CA  1 
ATOM   6111 C C   . GLU C 3 273 ? 164.634 87.266  140.950 1.00 161.02 ?  276 GLU C C   1 
ATOM   6112 O O   . GLU C 3 273 ? 165.016 86.097  141.081 1.00 160.06 ?  276 GLU C O   1 
ATOM   6113 C CB  . GLU C 3 273 ? 166.225 89.158  141.379 1.00 160.08 ?  276 GLU C CB  1 
ATOM   6114 C CG  . GLU C 3 273 ? 167.485 89.861  140.903 1.00 161.39 ?  276 GLU C CG  1 
ATOM   6115 C CD  . GLU C 3 273 ? 168.557 88.897  140.428 1.00 164.32 ?  276 GLU C CD  1 
ATOM   6116 O OE1 . GLU C 3 273 ? 168.604 87.754  140.930 1.00 164.07 ?  276 GLU C OE1 1 
ATOM   6117 O OE2 . GLU C 3 273 ? 169.356 89.284  139.550 1.00 164.00 -1 276 GLU C OE2 1 
ATOM   6118 N N   . LYS C 3 274 ? 163.429 87.669  141.360 1.00 154.16 ?  277 LYS C N   1 
ATOM   6119 C CA  . LYS C 3 274 ? 162.503 86.723  141.973 1.00 154.29 ?  277 LYS C CA  1 
ATOM   6120 C C   . LYS C 3 274 ? 161.997 85.703  140.960 1.00 154.30 ?  277 LYS C C   1 
ATOM   6121 O O   . LYS C 3 274 ? 161.841 84.521  141.288 1.00 156.13 ?  277 LYS C O   1 
ATOM   6122 C CB  . LYS C 3 274 ? 161.334 87.472  142.611 1.00 156.24 ?  277 LYS C CB  1 
ATOM   6123 C CG  . LYS C 3 274 ? 161.528 87.794  144.082 1.00 154.66 ?  277 LYS C CG  1 
ATOM   6124 C CD  . LYS C 3 274 ? 160.968 89.163  144.421 1.00 154.25 ?  277 LYS C CD  1 
ATOM   6125 C CE  . LYS C 3 274 ? 161.230 89.520  145.872 1.00 153.59 ?  277 LYS C CE  1 
ATOM   6126 N NZ  . LYS C 3 274 ? 161.098 88.336  146.762 1.00 152.52 1  277 LYS C NZ  1 
ATOM   6127 N N   . ILE C 3 275 ? 161.729 86.139  139.727 1.00 155.05 ?  278 ILE C N   1 
ATOM   6128 C CA  . ILE C 3 275 ? 161.233 85.224  138.705 1.00 157.17 ?  278 ILE C CA  1 
ATOM   6129 C C   . ILE C 3 275 ? 162.300 84.204  138.335 1.00 158.38 ?  278 ILE C C   1 
ATOM   6130 O O   . ILE C 3 275 ? 161.983 83.048  138.025 1.00 157.69 ?  278 ILE C O   1 
ATOM   6131 C CB  . ILE C 3 275 ? 160.740 86.020  137.482 1.00 155.36 ?  278 ILE C CB  1 
ATOM   6132 C CG1 . ILE C 3 275 ? 159.363 86.621  137.770 1.00 155.58 ?  278 ILE C CG1 1 
ATOM   6133 C CG2 . ILE C 3 275 ? 160.696 85.151  136.232 1.00 156.06 ?  278 ILE C CG2 1 
ATOM   6134 C CD1 . ILE C 3 275 ? 158.213 85.696  137.454 1.00 156.70 ?  278 ILE C CD1 1 
ATOM   6135 N N   . LYS C 3 276 ? 163.575 84.599  138.377 1.00 160.16 ?  279 LYS C N   1 
ATOM   6136 C CA  . LYS C 3 276 ? 164.649 83.665  138.049 1.00 159.34 ?  279 LYS C CA  1 
ATOM   6137 C C   . LYS C 3 276 ? 164.624 82.429  138.941 1.00 159.42 ?  279 LYS C C   1 
ATOM   6138 O O   . LYS C 3 276 ? 165.088 81.360  138.527 1.00 159.27 ?  279 LYS C O   1 
ATOM   6139 C CB  . LYS C 3 276 ? 166.002 84.366  138.155 1.00 159.19 ?  279 LYS C CB  1 
ATOM   6140 C CG  . LYS C 3 276 ? 166.466 85.011  136.862 1.00 157.39 ?  279 LYS C CG  1 
ATOM   6141 C CD  . LYS C 3 276 ? 167.442 86.140  137.139 1.00 158.92 ?  279 LYS C CD  1 
ATOM   6142 C CE  . LYS C 3 276 ? 168.639 85.648  137.933 1.00 159.03 ?  279 LYS C CE  1 
ATOM   6143 N NZ  . LYS C 3 276 ? 169.547 86.765  138.307 1.00 159.74 1  279 LYS C NZ  1 
ATOM   6144 N N   . LYS C 3 277 ? 164.095 82.545  140.159 1.00 161.67 ?  280 LYS C N   1 
ATOM   6145 C CA  . LYS C 3 277 ? 163.985 81.411  141.068 1.00 162.37 ?  280 LYS C CA  1 
ATOM   6146 C C   . LYS C 3 277 ? 162.536 81.026  141.336 1.00 162.35 ?  280 LYS C C   1 
ATOM   6147 O O   . LYS C 3 277 ? 162.149 79.877  141.104 1.00 161.03 ?  280 LYS C O   1 
ATOM   6148 C CB  . LYS C 3 277 ? 164.708 81.717  142.387 1.00 161.23 ?  280 LYS C CB  1 
ATOM   6149 C CG  . LYS C 3 277 ? 166.216 81.834  142.253 1.00 161.36 ?  280 LYS C CG  1 
ATOM   6150 C CD  . LYS C 3 277 ? 166.847 82.380  143.523 1.00 161.19 ?  280 LYS C CD  1 
ATOM   6151 C CE  . LYS C 3 277 ? 166.589 83.868  143.675 1.00 161.30 ?  280 LYS C CE  1 
ATOM   6152 N NZ  . LYS C 3 277 ? 167.363 84.448  144.808 1.00 160.58 1  280 LYS C NZ  1 
ATOM   6153 N N   . SER C 3 278 ? 161.712 81.965  141.822 1.00 164.50 ?  281 SER C N   1 
ATOM   6154 C CA  . SER C 3 278 ? 160.333 81.604  142.111 1.00 162.59 ?  281 SER C CA  1 
ATOM   6155 C C   . SER C 3 278 ? 159.450 81.829  140.888 1.00 164.21 ?  281 SER C C   1 
ATOM   6156 O O   . SER C 3 278 ? 159.732 82.705  140.064 1.00 162.87 ?  281 SER C O   1 
ATOM   6157 C CB  . SER C 3 278 ? 159.801 82.427  143.282 1.00 160.02 ?  281 SER C CB  1 
ATOM   6158 O OG  . SER C 3 278 ? 160.010 83.811  143.068 1.00 162.27 ?  281 SER C OG  1 
ATOM   6159 N N   . PRO C 3 279 ? 158.380 81.056  140.740 1.00 165.85 ?  282 PRO C N   1 
ATOM   6160 C CA  . PRO C 3 279 ? 157.462 81.251  139.619 1.00 164.88 ?  282 PRO C CA  1 
ATOM   6161 C C   . PRO C 3 279 ? 156.347 82.229  139.977 1.00 162.52 ?  282 PRO C C   1 
ATOM   6162 O O   . PRO C 3 279 ? 156.181 82.633  141.128 1.00 161.58 ?  282 PRO C O   1 
ATOM   6163 C CB  . PRO C 3 279 ? 156.897 79.841  139.376 1.00 162.88 ?  282 PRO C CB  1 
ATOM   6164 C CG  . PRO C 3 279 ? 157.297 79.012  140.588 1.00 161.76 ?  282 PRO C CG  1 
ATOM   6165 C CD  . PRO C 3 279 ? 157.985 79.908  141.570 1.00 162.56 ?  282 PRO C CD  1 
ATOM   6166 N N   . LEU C 3 280 ? 155.585 82.608  138.952 1.00 152.82 ?  283 LEU C N   1 
ATOM   6167 C CA  . LEU C 3 280 ? 154.433 83.477  139.146 1.00 154.88 ?  283 LEU C CA  1 
ATOM   6168 C C   . LEU C 3 280 ? 153.187 82.714  139.574 1.00 157.08 ?  283 LEU C C   1 
ATOM   6169 O O   . LEU C 3 280 ? 152.190 83.342  139.945 1.00 157.58 ?  283 LEU C O   1 
ATOM   6170 C CB  . LEU C 3 280 ? 154.142 84.259  137.861 1.00 153.41 ?  283 LEU C CB  1 
ATOM   6171 C CG  . LEU C 3 280 ? 153.355 85.565  138.013 1.00 152.22 ?  283 LEU C CG  1 
ATOM   6172 C CD1 . LEU C 3 280 ? 154.017 86.469  139.037 1.00 151.94 ?  283 LEU C CD1 1 
ATOM   6173 C CD2 . LEU C 3 280 ? 153.202 86.277  136.679 1.00 151.89 ?  283 LEU C CD2 1 
ATOM   6174 N N   . THR C 3 281 ? 153.224 81.381  139.542 1.00 161.59 ?  284 THR C N   1 
ATOM   6175 C CA  . THR C 3 281 ? 152.040 80.591  139.866 1.00 161.99 ?  284 THR C CA  1 
ATOM   6176 C C   . THR C 3 281 ? 151.643 80.742  141.332 1.00 160.73 ?  284 THR C C   1 
ATOM   6177 O O   . THR C 3 281 ? 150.453 80.660  141.661 1.00 159.23 ?  284 THR C O   1 
ATOM   6178 C CB  . THR C 3 281 ? 152.293 79.123  139.503 1.00 161.03 ?  284 THR C CB  1 
ATOM   6179 O OG1 . THR C 3 281 ? 152.070 78.936  138.099 1.00 160.41 ?  284 THR C OG1 1 
ATOM   6180 C CG2 . THR C 3 281 ? 151.382 78.181  140.277 1.00 158.72 ?  284 THR C CG2 1 
ATOM   6181 N N   . ILE C 3 282 ? 152.611 81.001  142.216 1.00 157.46 ?  285 ILE C N   1 
ATOM   6182 C CA  . ILE C 3 282 ? 152.313 81.076  143.645 1.00 157.84 ?  285 ILE C CA  1 
ATOM   6183 C C   . ILE C 3 282 ? 151.294 82.173  143.926 1.00 157.15 ?  285 ILE C C   1 
ATOM   6184 O O   . ILE C 3 282 ? 150.345 81.976  144.695 1.00 156.44 ?  285 ILE C O   1 
ATOM   6185 C CB  . ILE C 3 282 ? 153.608 81.279  144.454 1.00 156.47 ?  285 ILE C CB  1 
ATOM   6186 C CG1 . ILE C 3 282 ? 153.284 81.718  145.882 1.00 154.90 ?  285 ILE C CG1 1 
ATOM   6187 C CG2 . ILE C 3 282 ? 154.507 82.294  143.780 1.00 155.17 ?  285 ILE C CG2 1 
ATOM   6188 C CD1 . ILE C 3 282 ? 154.379 81.411  146.876 1.00 154.01 ?  285 ILE C CD1 1 
ATOM   6189 N N   . CYS C 3 283 ? 151.463 83.338  143.305 1.00 157.36 ?  286 CYS C N   1 
ATOM   6190 C CA  . CYS C 3 283 ? 150.513 84.427  143.480 1.00 157.26 ?  286 CYS C CA  1 
ATOM   6191 C C   . CYS C 3 283 ? 149.314 84.331  142.549 1.00 156.06 ?  286 CYS C C   1 
ATOM   6192 O O   . CYS C 3 283 ? 148.207 84.710  142.948 1.00 156.20 ?  286 CYS C O   1 
ATOM   6193 C CB  . CYS C 3 283 ? 151.203 85.774  143.263 1.00 158.71 ?  286 CYS C CB  1 
ATOM   6194 S SG  . CYS C 3 283 ? 150.231 87.201  143.797 1.00 165.77 ?  286 CYS C SG  1 
ATOM   6195 N N   . TYR C 3 284 ? 149.503 83.842  141.331 1.00 152.45 ?  287 TYR C N   1 
ATOM   6196 C CA  . TYR C 3 284 ? 148.413 83.715  140.364 1.00 154.70 ?  287 TYR C CA  1 
ATOM   6197 C C   . TYR C 3 284 ? 148.116 82.241  140.145 1.00 154.82 ?  287 TYR C C   1 
ATOM   6198 O O   . TYR C 3 284 ? 148.936 81.535  139.527 1.00 152.34 ?  287 TYR C O   1 
ATOM   6199 C CB  . TYR C 3 284 ? 148.772 84.399  139.045 1.00 153.69 ?  287 TYR C CB  1 
ATOM   6200 C CG  . TYR C 3 284 ? 148.624 85.907  139.071 1.00 152.45 ?  287 TYR C CG  1 
ATOM   6201 C CD1 . TYR C 3 284 ? 148.629 86.608  140.268 1.00 150.48 ?  287 TYR C CD1 1 
ATOM   6202 C CD2 . TYR C 3 284 ? 148.478 86.628  137.897 1.00 150.84 ?  287 TYR C CD2 1 
ATOM   6203 C CE1 . TYR C 3 284 ? 148.494 87.979  140.294 1.00 148.91 ?  287 TYR C CE1 1 
ATOM   6204 C CE2 . TYR C 3 284 ? 148.343 87.999  137.913 1.00 149.88 ?  287 TYR C CE2 1 
ATOM   6205 C CZ  . TYR C 3 284 ? 148.351 88.669  139.114 1.00 150.26 ?  287 TYR C CZ  1 
ATOM   6206 O OH  . TYR C 3 284 ? 148.216 90.036  139.137 1.00 152.44 ?  287 TYR C OH  1 
ATOM   6207 N N   . PRO C 3 285 ? 146.975 81.733  140.623 1.00 165.82 ?  288 PRO C N   1 
ATOM   6208 C CA  . PRO C 3 285 ? 146.740 80.278  140.569 1.00 164.46 ?  288 PRO C CA  1 
ATOM   6209 C C   . PRO C 3 285 ? 146.815 79.698  139.169 1.00 163.88 ?  288 PRO C C   1 
ATOM   6210 O O   . PRO C 3 285 ? 147.332 78.589  138.989 1.00 161.85 ?  288 PRO C O   1 
ATOM   6211 C CB  . PRO C 3 285 ? 145.331 80.132  141.165 1.00 163.54 ?  288 PRO C CB  1 
ATOM   6212 C CG  . PRO C 3 285 ? 145.116 81.375  141.964 1.00 163.49 ?  288 PRO C CG  1 
ATOM   6213 C CD  . PRO C 3 285 ? 145.851 82.457  141.238 1.00 162.83 ?  288 PRO C CD  1 
ATOM   6214 N N   . GLU C 3 286 ? 146.323 80.421  138.169 1.00 163.39 ?  289 GLU C N   1 
ATOM   6215 C CA  . GLU C 3 286 ? 146.362 79.975  136.784 1.00 161.44 ?  289 GLU C CA  1 
ATOM   6216 C C   . GLU C 3 286 ? 147.297 80.885  136.002 1.00 163.56 ?  289 GLU C C   1 
ATOM   6217 O O   . GLU C 3 286 ? 147.124 82.109  136.002 1.00 165.64 ?  289 GLU C O   1 
ATOM   6218 C CB  . GLU C 3 286 ? 144.961 79.973  136.171 1.00 160.85 ?  289 GLU C CB  1 
ATOM   6219 C CG  . GLU C 3 286 ? 144.135 81.203  136.501 1.00 163.22 ?  289 GLU C CG  1 
ATOM   6220 C CD  . GLU C 3 286 ? 144.172 82.238  135.397 1.00 166.14 ?  289 GLU C CD  1 
ATOM   6221 O OE1 . GLU C 3 286 ? 144.434 81.859  134.236 1.00 164.52 ?  289 GLU C OE1 1 
ATOM   6222 O OE2 . GLU C 3 286 ? 143.944 83.431  135.690 1.00 165.44 -1 289 GLU C OE2 1 
ATOM   6223 N N   . TYR C 3 287 ? 148.292 80.289  135.351 1.00 164.98 ?  290 TYR C N   1 
ATOM   6224 C CA  . TYR C 3 287 ? 149.229 81.048  134.528 1.00 165.93 ?  290 TYR C CA  1 
ATOM   6225 C C   . TYR C 3 287 ? 149.906 80.089  133.566 1.00 166.19 ?  290 TYR C C   1 
ATOM   6226 O O   . TYR C 3 287 ? 150.600 79.164  134.001 1.00 163.12 ?  290 TYR C O   1 
ATOM   6227 C CB  . TYR C 3 287 ? 150.263 81.770  135.388 1.00 163.66 ?  290 TYR C CB  1 
ATOM   6228 C CG  . TYR C 3 287 ? 151.360 82.422  134.581 1.00 164.09 ?  290 TYR C CG  1 
ATOM   6229 C CD1 . TYR C 3 287 ? 151.060 83.247  133.508 1.00 161.99 ?  290 TYR C CD1 1 
ATOM   6230 C CD2 . TYR C 3 287 ? 152.695 82.212  134.892 1.00 164.92 ?  290 TYR C CD2 1 
ATOM   6231 C CE1 . TYR C 3 287 ? 152.057 83.844  132.766 1.00 162.75 ?  290 TYR C CE1 1 
ATOM   6232 C CE2 . TYR C 3 287 ? 153.701 82.805  134.155 1.00 165.72 ?  290 TYR C CE2 1 
ATOM   6233 C CZ  . TYR C 3 287 ? 153.376 83.620  133.094 1.00 165.59 ?  290 TYR C CZ  1 
ATOM   6234 O OH  . TYR C 3 287 ? 154.374 84.212  132.357 1.00 165.04 ?  290 TYR C OH  1 
ATOM   6235 N N   . ALA C 3 288 ? 149.713 80.308  132.271 1.00 167.36 ?  291 ALA C N   1 
ATOM   6236 C CA  . ALA C 3 288 ? 150.316 79.489  131.224 1.00 165.81 ?  291 ALA C CA  1 
ATOM   6237 C C   . ALA C 3 288 ? 151.385 80.336  130.541 1.00 165.73 ?  291 ALA C C   1 
ATOM   6238 O O   . ALA C 3 288 ? 151.133 80.986  129.526 1.00 164.73 ?  291 ALA C O   1 
ATOM   6239 C CB  . ALA C 3 288 ? 149.264 78.999  130.234 1.00 162.93 ?  291 ALA C CB  1 
ATOM   6240 N N   . GLY C 3 289 ? 152.586 80.323  131.110 1.00 165.19 ?  292 GLY C N   1 
ATOM   6241 C CA  . GLY C 3 289 ? 153.693 81.076  130.557 1.00 164.72 ?  292 GLY C CA  1 
ATOM   6242 C C   . GLY C 3 289 ? 155.015 80.710  131.195 1.00 165.30 ?  292 GLY C C   1 
ATOM   6243 O O   . GLY C 3 289 ? 155.057 80.288  132.354 1.00 164.08 ?  292 GLY C O   1 
ATOM   6244 N N   . SER C 3 290 ? 156.102 80.872  130.449 1.00 170.38 ?  293 SER C N   1 
ATOM   6245 C CA  . SER C 3 290 ? 157.414 80.519  130.962 1.00 171.48 ?  293 SER C CA  1 
ATOM   6246 C C   . SER C 3 290 ? 157.862 81.523  132.020 1.00 170.87 ?  293 SER C C   1 
ATOM   6247 O O   . SER C 3 290 ? 157.408 82.670  132.062 1.00 168.82 ?  293 SER C O   1 
ATOM   6248 C CB  . SER C 3 290 ? 158.436 80.457  129.827 1.00 170.07 ?  293 SER C CB  1 
ATOM   6249 O OG  . SER C 3 290 ? 159.760 80.470  130.331 1.00 170.15 ?  293 SER C OG  1 
ATOM   6250 N N   . ASN C 3 291 ? 158.777 81.077  132.881 1.00 167.37 ?  294 ASN C N   1 
ATOM   6251 C CA  . ASN C 3 291 ? 159.303 81.914  133.958 1.00 166.65 ?  294 ASN C CA  1 
ATOM   6252 C C   . ASN C 3 291 ? 160.325 82.912  133.406 1.00 166.40 ?  294 ASN C C   1 
ATOM   6253 O O   . ASN C 3 291 ? 161.492 82.948  133.795 1.00 164.05 ?  294 ASN C O   1 
ATOM   6254 C CB  . ASN C 3 291 ? 159.909 81.044  135.050 1.00 165.74 ?  294 ASN C CB  1 
ATOM   6255 C CG  . ASN C 3 291 ? 158.960 80.821  136.209 1.00 166.11 ?  294 ASN C CG  1 
ATOM   6256 O OD1 . ASN C 3 291 ? 157.851 81.353  136.231 1.00 166.14 ?  294 ASN C OD1 1 
ATOM   6257 N ND2 . ASN C 3 291 ? 159.393 80.028  137.182 1.00 164.98 ?  294 ASN C ND2 1 
ATOM   6258 N N   . THR C 3 292 ? 159.852 83.735  132.476 1.00 169.96 ?  295 THR C N   1 
ATOM   6259 C CA  . THR C 3 292 ? 160.646 84.782  131.854 1.00 169.90 ?  295 THR C CA  1 
ATOM   6260 C C   . THR C 3 292 ? 160.070 86.137  132.238 1.00 170.21 ?  295 THR C C   1 
ATOM   6261 O O   . THR C 3 292 ? 158.853 86.280  132.393 1.00 169.85 ?  295 THR C O   1 
ATOM   6262 C CB  . THR C 3 292 ? 160.662 84.635  130.331 1.00 168.97 ?  295 THR C CB  1 
ATOM   6263 O OG1 . THR C 3 292 ? 159.317 84.633  129.837 1.00 168.29 ?  295 THR C OG1 1 
ATOM   6264 C CG2 . THR C 3 292 ? 161.343 83.336  129.932 1.00 166.31 ?  295 THR C CG2 1 
ATOM   6265 N N   . TYR C 3 293 ? 160.949 87.130  132.388 1.00 157.69 ?  296 TYR C N   1 
ATOM   6266 C CA  . TYR C 3 293 ? 160.506 88.435  132.866 1.00 155.97 ?  296 TYR C CA  1 
ATOM   6267 C C   . TYR C 3 293 ? 159.516 89.079  131.906 1.00 156.97 ?  296 TYR C C   1 
ATOM   6268 O O   . TYR C 3 293 ? 158.534 89.687  132.340 1.00 158.11 ?  296 TYR C O   1 
ATOM   6269 C CB  . TYR C 3 293 ? 161.699 89.361  133.078 1.00 154.30 ?  296 TYR C CB  1 
ATOM   6270 C CG  . TYR C 3 293 ? 161.336 90.825  132.965 1.00 158.03 ?  296 TYR C CG  1 
ATOM   6271 C CD1 . TYR C 3 293 ? 160.593 91.455  133.954 1.00 156.77 ?  296 TYR C CD1 1 
ATOM   6272 C CD2 . TYR C 3 293 ? 161.726 91.574  131.864 1.00 158.45 ?  296 TYR C CD2 1 
ATOM   6273 C CE1 . TYR C 3 293 ? 160.253 92.789  133.852 1.00 156.51 ?  296 TYR C CE1 1 
ATOM   6274 C CE2 . TYR C 3 293 ? 161.392 92.909  131.755 1.00 157.70 ?  296 TYR C CE2 1 
ATOM   6275 C CZ  . TYR C 3 293 ? 160.656 93.511  132.751 1.00 157.75 ?  296 TYR C CZ  1 
ATOM   6276 O OH  . TYR C 3 293 ? 160.323 94.841  132.643 1.00 156.58 ?  296 TYR C OH  1 
ATOM   6277 N N   . GLU C 3 294 ? 159.764 88.976  130.601 1.00 156.66 ?  297 GLU C N   1 
ATOM   6278 C CA  . GLU C 3 294 ? 158.919 89.676  129.639 1.00 156.88 ?  297 GLU C CA  1 
ATOM   6279 C C   . GLU C 3 294 ? 157.484 89.166  129.690 1.00 159.62 ?  297 GLU C C   1 
ATOM   6280 O O   . GLU C 3 294 ? 156.538 89.951  129.832 1.00 161.21 ?  297 GLU C O   1 
ATOM   6281 C CB  . GLU C 3 294 ? 159.494 89.529  128.232 1.00 157.64 ?  297 GLU C CB  1 
ATOM   6282 C CG  . GLU C 3 294 ? 158.739 90.318  127.181 1.00 159.88 ?  297 GLU C CG  1 
ATOM   6283 C CD  . GLU C 3 294 ? 158.467 91.743  127.614 1.00 161.31 ?  297 GLU C CD  1 
ATOM   6284 O OE1 . GLU C 3 294 ? 159.417 92.554  127.622 1.00 160.70 ?  297 GLU C OE1 1 
ATOM   6285 O OE2 . GLU C 3 294 ? 157.304 92.053  127.948 1.00 159.42 -1 297 GLU C OE2 1 
ATOM   6286 N N   . GLU C 3 295 ? 157.304 87.848  129.585 1.00 157.40 ?  298 GLU C N   1 
ATOM   6287 C CA  . GLU C 3 295 ? 155.957 87.285  129.588 1.00 157.15 ?  298 GLU C CA  1 
ATOM   6288 C C   . GLU C 3 295 ? 155.264 87.508  130.925 1.00 158.29 ?  298 GLU C C   1 
ATOM   6289 O O   . GLU C 3 295 ? 154.080 87.861  130.964 1.00 157.35 ?  298 GLU C O   1 
ATOM   6290 C CB  . GLU C 3 295 ? 156.011 85.796  129.252 1.00 158.78 ?  298 GLU C CB  1 
ATOM   6291 C CG  . GLU C 3 295 ? 155.332 85.431  127.945 1.00 158.91 ?  298 GLU C CG  1 
ATOM   6292 C CD  . GLU C 3 295 ? 155.318 83.937  127.694 1.00 160.73 ?  298 GLU C CD  1 
ATOM   6293 O OE1 . GLU C 3 295 ? 156.317 83.268  128.030 1.00 158.89 ?  298 GLU C OE1 1 
ATOM   6294 O OE2 . GLU C 3 295 ? 154.307 83.432  127.163 1.00 160.55 -1 298 GLU C OE2 1 
ATOM   6295 N N   . ALA C 3 296 ? 155.984 87.309  132.032 1.00 150.49 ?  299 ALA C N   1 
ATOM   6296 C CA  . ALA C 3 296 ? 155.383 87.499  133.348 1.00 148.97 ?  299 ALA C CA  1 
ATOM   6297 C C   . ALA C 3 296 ? 154.953 88.945  133.556 1.00 149.04 ?  299 ALA C C   1 
ATOM   6298 O O   . ALA C 3 296 ? 153.849 89.210  134.047 1.00 149.57 ?  299 ALA C O   1 
ATOM   6299 C CB  . ALA C 3 296 ? 156.364 87.071  134.438 1.00 145.21 ?  299 ALA C CB  1 
ATOM   6300 N N   . ALA C 3 297 ? 155.812 89.894  133.183 1.00 137.73 ?  300 ALA C N   1 
ATOM   6301 C CA  . ALA C 3 297 ? 155.485 91.305  133.334 1.00 133.32 ?  300 ALA C CA  1 
ATOM   6302 C C   . ALA C 3 297 ? 154.314 91.700  132.448 1.00 135.87 ?  300 ALA C C   1 
ATOM   6303 O O   . ALA C 3 297 ? 153.440 92.462  132.873 1.00 138.08 ?  300 ALA C O   1 
ATOM   6304 C CB  . ALA C 3 297 ? 156.710 92.159  133.018 1.00 137.01 ?  300 ALA C CB  1 
ATOM   6305 N N   . ALA C 3 298 ? 154.280 91.199  131.210 1.00 138.84 ?  301 ALA C N   1 
ATOM   6306 C CA  . ALA C 3 298 ? 153.150 91.492  130.336 1.00 135.95 ?  301 ALA C CA  1 
ATOM   6307 C C   . ALA C 3 298 ? 151.858 90.929  130.906 1.00 136.60 ?  301 ALA C C   1 
ATOM   6308 O O   . ALA C 3 298 ? 150.810 91.584  130.857 1.00 134.95 ?  301 ALA C O   1 
ATOM   6309 C CB  . ALA C 3 298 ? 153.409 90.936  128.938 1.00 134.43 ?  301 ALA C CB  1 
ATOM   6310 N N   . TYR C 3 299 ? 151.912 89.716  131.459 1.00 140.04 ?  302 TYR C N   1 
ATOM   6311 C CA  . TYR C 3 299 ? 150.715 89.121  132.039 1.00 141.74 ?  302 TYR C CA  1 
ATOM   6312 C C   . TYR C 3 299 ? 150.249 89.899  133.260 1.00 142.56 ?  302 TYR C C   1 
ATOM   6313 O O   . TYR C 3 299 ? 149.046 90.080  133.461 1.00 140.09 ?  302 TYR C O   1 
ATOM   6314 C CB  . TYR C 3 299 ? 150.974 87.659  132.398 1.00 141.32 ?  302 TYR C CB  1 
ATOM   6315 C CG  . TYR C 3 299 ? 149.768 86.958  132.974 1.00 142.57 ?  302 TYR C CG  1 
ATOM   6316 C CD1 . TYR C 3 299 ? 148.563 86.938  132.286 1.00 142.48 ?  302 TYR C CD1 1 
ATOM   6317 C CD2 . TYR C 3 299 ? 149.830 86.322  134.203 1.00 141.43 ?  302 TYR C CD2 1 
ATOM   6318 C CE1 . TYR C 3 299 ? 147.457 86.302  132.804 1.00 141.82 ?  302 TYR C CE1 1 
ATOM   6319 C CE2 . TYR C 3 299 ? 148.730 85.680  134.727 1.00 142.63 ?  302 TYR C CE2 1 
ATOM   6320 C CZ  . TYR C 3 299 ? 147.544 85.675  134.025 1.00 143.39 ?  302 TYR C CZ  1 
ATOM   6321 O OH  . TYR C 3 299 ? 146.441 85.038  134.544 1.00 142.14 ?  302 TYR C OH  1 
ATOM   6322 N N   . ILE C 3 300 ? 151.186 90.370  134.087 1.00 128.54 ?  303 ILE C N   1 
ATOM   6323 C CA  . ILE C 3 300 ? 150.809 91.154  135.259 1.00 124.29 ?  303 ILE C CA  1 
ATOM   6324 C C   . ILE C 3 300 ? 150.206 92.489  134.840 1.00 120.68 ?  303 ILE C C   1 
ATOM   6325 O O   . ILE C 3 300 ? 149.217 92.950  135.423 1.00 121.50 ?  303 ILE C O   1 
ATOM   6326 C CB  . ILE C 3 300 ? 152.020 91.342  136.190 1.00 119.35 ?  303 ILE C CB  1 
ATOM   6327 C CG1 . ILE C 3 300 ? 152.316 90.042  136.935 1.00 122.63 ?  303 ILE C CG1 1 
ATOM   6328 C CG2 . ILE C 3 300 ? 151.765 92.462  137.178 1.00 120.86 ?  303 ILE C CG2 1 
ATOM   6329 C CD1 . ILE C 3 300 ? 153.367 90.183  138.004 1.00 124.38 ?  303 ILE C CD1 1 
ATOM   6330 N N   . GLN C 3 301 ? 150.784 93.132  133.825 1.00 122.26 ?  304 GLN C N   1 
ATOM   6331 C CA  . GLN C 3 301 ? 150.209 94.372  133.320 1.00 119.70 ?  304 GLN C CA  1 
ATOM   6332 C C   . GLN C 3 301 ? 148.799 94.147  132.792 1.00 121.68 ?  304 GLN C C   1 
ATOM   6333 O O   . GLN C 3 301 ? 147.889 94.933  133.073 1.00 121.72 ?  304 GLN C O   1 
ATOM   6334 C CB  . GLN C 3 301 ? 151.100 94.959  132.228 1.00 118.19 ?  304 GLN C CB  1 
ATOM   6335 C CG  . GLN C 3 301 ? 150.674 96.337  131.770 1.00 117.40 ?  304 GLN C CG  1 
ATOM   6336 C CD  . GLN C 3 301 ? 150.885 96.554  130.290 1.00 121.63 ?  304 GLN C CD  1 
ATOM   6337 O OE1 . GLN C 3 301 ? 151.961 96.288  129.760 1.00 121.87 ?  304 GLN C OE1 1 
ATOM   6338 N NE2 . GLN C 3 301 ? 149.858 97.051  129.613 1.00 122.09 ?  304 GLN C NE2 1 
ATOM   6339 N N   . CYS C 3 302 ? 148.596 93.066  132.037 1.00 133.53 ?  305 CYS C N   1 
ATOM   6340 C CA  . CYS C 3 302 ? 147.267 92.769  131.519 1.00 132.20 ?  305 CYS C CA  1 
ATOM   6341 C C   . CYS C 3 302 ? 146.289 92.474  132.648 1.00 133.05 ?  305 CYS C C   1 
ATOM   6342 O O   . CYS C 3 302 ? 145.121 92.875  132.586 1.00 133.61 ?  305 CYS C O   1 
ATOM   6343 C CB  . CYS C 3 302 ? 147.336 91.593  130.546 1.00 134.30 ?  305 CYS C CB  1 
ATOM   6344 S SG  . CYS C 3 302 ? 145.729 90.915  130.077 1.00 144.03 ?  305 CYS C SG  1 
ATOM   6345 N N   . GLN C 3 303 ? 146.753 91.767  133.685 1.00 128.71 ?  306 GLN C N   1 
ATOM   6346 C CA  . GLN C 3 303 ? 145.894 91.395  134.805 1.00 131.28 ?  306 GLN C CA  1 
ATOM   6347 C C   . GLN C 3 303 ? 145.537 92.596  135.666 1.00 128.99 ?  306 GLN C C   1 
ATOM   6348 O O   . GLN C 3 303 ? 144.499 92.591  136.334 1.00 127.97 ?  306 GLN C O   1 
ATOM   6349 C CB  . GLN C 3 303 ? 146.572 90.321  135.653 1.00 128.13 ?  306 GLN C CB  1 
ATOM   6350 C CG  . GLN C 3 303 ? 146.111 88.907  135.343 1.00 132.15 ?  306 GLN C CG  1 
ATOM   6351 C CD  . GLN C 3 303 ? 144.601 88.786  135.288 1.00 134.15 ?  306 GLN C CD  1 
ATOM   6352 O OE1 . GLN C 3 303 ? 144.006 88.777  134.210 1.00 132.32 ?  306 GLN C OE1 1 
ATOM   6353 N NE2 . GLN C 3 303 ? 143.973 88.694  136.454 1.00 129.59 ?  306 GLN C NE2 1 
ATOM   6354 N N   . PHE C 3 304 ? 146.392 93.613  135.689 1.00 117.96 ?  307 PHE C N   1 
ATOM   6355 C CA  . PHE C 3 304 ? 146.011 94.865  136.328 1.00 112.09 ?  307 PHE C CA  1 
ATOM   6356 C C   . PHE C 3 304 ? 145.082 95.678  135.439 1.00 112.80 ?  307 PHE C C   1 
ATOM   6357 O O   . PHE C 3 304 ? 144.198 96.382  135.937 1.00 114.97 ?  307 PHE C O   1 
ATOM   6358 C CB  . PHE C 3 304 ? 147.253 95.676  136.681 1.00 106.98 ?  307 PHE C CB  1 
ATOM   6359 C CG  . PHE C 3 304 ? 147.632 95.591  138.121 1.00 105.35 ?  307 PHE C CG  1 
ATOM   6360 C CD1 . PHE C 3 304 ? 146.978 96.356  139.064 1.00 110.04 ?  307 PHE C CD1 1 
ATOM   6361 C CD2 . PHE C 3 304 ? 148.628 94.731  138.536 1.00 108.76 ?  307 PHE C CD2 1 
ATOM   6362 C CE1 . PHE C 3 304 ? 147.321 96.277  140.389 1.00 114.99 ?  307 PHE C CE1 1 
ATOM   6363 C CE2 . PHE C 3 304 ? 148.974 94.646  139.861 1.00 108.88 ?  307 PHE C CE2 1 
ATOM   6364 C CZ  . PHE C 3 304 ? 148.321 95.420  140.789 1.00 114.08 ?  307 PHE C CZ  1 
ATOM   6365 N N   . GLU C 3 305 ? 145.264 95.588  134.122 1.00 118.58 ?  308 GLU C N   1 
ATOM   6366 C CA  . GLU C 3 305 ? 144.513 96.449  133.219 1.00 115.10 ?  308 GLU C CA  1 
ATOM   6367 C C   . GLU C 3 305 ? 143.078 95.982  133.024 1.00 117.30 ?  308 GLU C C   1 
ATOM   6368 O O   . GLU C 3 305 ? 142.196 96.816  132.792 1.00 119.85 ?  308 GLU C O   1 
ATOM   6369 C CB  . GLU C 3 305 ? 145.224 96.547  131.874 1.00 116.98 ?  308 GLU C CB  1 
ATOM   6370 C CG  . GLU C 3 305 ? 145.014 97.877  131.182 1.00 120.68 ?  308 GLU C CG  1 
ATOM   6371 C CD  . GLU C 3 305 ? 146.182 98.270  130.308 1.00 124.00 ?  308 GLU C CD  1 
ATOM   6372 O OE1 . GLU C 3 305 ? 147.330 97.937  130.664 1.00 119.88 ?  308 GLU C OE1 1 
ATOM   6373 O OE2 . GLU C 3 305 ? 145.950 98.919  129.267 1.00 122.45 -1 308 GLU C OE2 1 
ATOM   6374 N N   . ASP C 3 306 ? 142.809 94.674  133.092 1.00 125.69 ?  309 ASP C N   1 
ATOM   6375 C CA  . ASP C 3 306 ? 141.430 94.263  132.826 1.00 129.88 ?  309 ASP C CA  1 
ATOM   6376 C C   . ASP C 3 306 ? 140.499 94.620  133.974 1.00 130.26 ?  309 ASP C C   1 
ATOM   6377 O O   . ASP C 3 306 ? 139.278 94.535  133.811 1.00 127.82 ?  309 ASP C O   1 
ATOM   6378 C CB  . ASP C 3 306 ? 141.309 92.759  132.574 1.00 131.69 ?  309 ASP C CB  1 
ATOM   6379 C CG  . ASP C 3 306 ? 142.177 91.948  133.484 1.00 135.84 ?  309 ASP C CG  1 
ATOM   6380 O OD1 . ASP C 3 306 ? 143.133 92.517  134.022 1.00 134.49 ?  309 ASP C OD1 1 
ATOM   6381 O OD2 . ASP C 3 306 ? 141.908 90.740  133.655 1.00 133.97 -1 309 ASP C OD2 1 
ATOM   6382 N N   . LEU C 3 307 ? 141.049 95.009  135.127 1.00 122.83 ?  310 LEU C N   1 
ATOM   6383 C CA  . LEU C 3 307 ? 140.236 95.421  136.263 1.00 119.11 ?  310 LEU C CA  1 
ATOM   6384 C C   . LEU C 3 307 ? 139.438 96.681  135.968 1.00 118.17 ?  310 LEU C C   1 
ATOM   6385 O O   . LEU C 3 307 ? 138.498 96.991  136.706 1.00 120.36 ?  310 LEU C O   1 
ATOM   6386 C CB  . LEU C 3 307 ? 141.126 95.648  137.485 1.00 115.14 ?  310 LEU C CB  1 
ATOM   6387 C CG  . LEU C 3 307 ? 141.692 94.405  138.170 1.00 115.54 ?  310 LEU C CG  1 
ATOM   6388 C CD1 . LEU C 3 307 ? 142.755 94.795  139.176 1.00 115.99 ?  310 LEU C CD1 1 
ATOM   6389 C CD2 . LEU C 3 307 ? 140.586 93.621  138.842 1.00 116.42 ?  310 LEU C CD2 1 
ATOM   6390 N N   . ASN C 3 308 ? 139.792 97.409  134.916 1.00 117.45 ?  311 ASN C N   1 
ATOM   6391 C CA  . ASN C 3 308 ? 139.050 98.595  134.522 1.00 118.24 ?  311 ASN C CA  1 
ATOM   6392 C C   . ASN C 3 308 ? 137.741 98.188  133.860 1.00 120.54 ?  311 ASN C C   1 
ATOM   6393 O O   . ASN C 3 308 ? 137.741 97.512  132.828 1.00 124.01 ?  311 ASN C O   1 
ATOM   6394 C CB  . ASN C 3 308 ? 139.890 99.442  133.568 1.00 116.19 ?  311 ASN C CB  1 
ATOM   6395 C CG  . ASN C 3 308 ? 139.204 100.727 133.171 1.00 119.31 ?  311 ASN C CG  1 
ATOM   6396 O OD1 . ASN C 3 308 ? 138.257 101.166 133.820 1.00 122.69 ?  311 ASN C OD1 1 
ATOM   6397 N ND2 . ASN C 3 308 ? 139.685 101.344 132.101 1.00 117.16 ?  311 ASN C ND2 1 
ATOM   6398 N N   . LYS C 3 309 ? 136.624 98.601  134.456 1.00 121.85 ?  312 LYS C N   1 
ATOM   6399 C CA  . LYS C 3 309 ? 135.318 98.284  133.895 1.00 121.79 ?  312 LYS C CA  1 
ATOM   6400 C C   . LYS C 3 309 ? 134.851 99.340  132.904 1.00 124.94 ?  312 LYS C C   1 
ATOM   6401 O O   . LYS C 3 309 ? 134.214 99.008  131.899 1.00 128.03 ?  312 LYS C O   1 
ATOM   6402 C CB  . LYS C 3 309 ? 134.284 98.128  135.014 1.00 123.80 ?  312 LYS C CB  1 
ATOM   6403 C CG  . LYS C 3 309 ? 134.661 97.114  136.083 1.00 125.89 ?  312 LYS C CG  1 
ATOM   6404 C CD  . LYS C 3 309 ? 135.146 95.810  135.476 1.00 123.51 ?  312 LYS C CD  1 
ATOM   6405 C CE  . LYS C 3 309 ? 135.874 94.963  136.507 1.00 124.44 ?  312 LYS C CE  1 
ATOM   6406 N NZ  . LYS C 3 309 ? 135.535 95.370  137.898 1.00 119.66 1  312 LYS C NZ  1 
ATOM   6407 N N   . ARG C 3 310 ? 135.154 100.609 133.168 1.00 132.18 ?  313 ARG C N   1 
ATOM   6408 C CA  . ARG C 3 310 ? 134.797 101.700 132.263 1.00 130.79 ?  313 ARG C CA  1 
ATOM   6409 C C   . ARG C 3 310 ? 135.950 101.945 131.289 1.00 131.95 ?  313 ARG C C   1 
ATOM   6410 O O   . ARG C 3 310 ? 136.649 102.958 131.328 1.00 130.12 ?  313 ARG C O   1 
ATOM   6411 C CB  . ARG C 3 310 ? 134.451 102.953 133.057 1.00 130.81 ?  313 ARG C CB  1 
ATOM   6412 C CG  . ARG C 3 310 ? 135.275 103.127 134.320 1.00 131.09 ?  313 ARG C CG  1 
ATOM   6413 C CD  . ARG C 3 310 ? 134.453 103.750 135.432 1.00 134.38 ?  313 ARG C CD  1 
ATOM   6414 N NE  . ARG C 3 310 ? 133.628 102.764 136.120 1.00 136.81 ?  313 ARG C NE  1 
ATOM   6415 C CZ  . ARG C 3 310 ? 132.646 103.064 136.958 1.00 133.56 ?  313 ARG C CZ  1 
ATOM   6416 N NH1 . ARG C 3 310 ? 132.334 104.319 137.237 1.00 132.60 1  313 ARG C NH1 1 
ATOM   6417 N NH2 . ARG C 3 310 ? 131.959 102.080 137.530 1.00 127.68 ?  313 ARG C NH2 1 
ATOM   6418 N N   . LYS C 3 311 ? 136.138 100.973 130.394 1.00 129.93 ?  314 LYS C N   1 
ATOM   6419 C CA  . LYS C 3 311 ? 137.246 101.033 129.449 1.00 130.41 ?  314 LYS C CA  1 
ATOM   6420 C C   . LYS C 3 311 ? 137.075 102.137 128.416 1.00 130.90 ?  314 LYS C C   1 
ATOM   6421 O O   . LYS C 3 311 ? 138.048 102.490 127.741 1.00 130.47 ?  314 LYS C O   1 
ATOM   6422 C CB  . LYS C 3 311 ? 137.406 99.689  128.739 1.00 128.29 ?  314 LYS C CB  1 
ATOM   6423 C CG  . LYS C 3 311 ? 138.109 98.629  129.564 1.00 128.62 ?  314 LYS C CG  1 
ATOM   6424 C CD  . LYS C 3 311 ? 139.235 97.983  128.780 1.00 129.78 ?  314 LYS C CD  1 
ATOM   6425 C CE  . LYS C 3 311 ? 139.767 96.755  129.495 1.00 131.49 ?  314 LYS C CE  1 
ATOM   6426 N NZ  . LYS C 3 311 ? 138.697 96.046  130.247 1.00 130.85 1  314 LYS C NZ  1 
ATOM   6427 N N   . ASP C 3 312 ? 135.872 102.690 128.277 1.00 136.55 ?  315 ASP C N   1 
ATOM   6428 C CA  . ASP C 3 312 ? 135.611 103.704 127.265 1.00 137.58 ?  315 ASP C CA  1 
ATOM   6429 C C   . ASP C 3 312 ? 135.977 105.106 127.741 1.00 138.96 ?  315 ASP C C   1 
ATOM   6430 O O   . ASP C 3 312 ? 136.632 105.859 127.015 1.00 139.62 ?  315 ASP C O   1 
ATOM   6431 C CB  . ASP C 3 312 ? 134.138 103.660 126.848 1.00 136.48 ?  315 ASP C CB  1 
ATOM   6432 C CG  . ASP C 3 312 ? 133.197 103.625 128.036 1.00 140.29 ?  315 ASP C CG  1 
ATOM   6433 O OD1 . ASP C 3 312 ? 133.681 103.732 129.182 1.00 142.89 ?  315 ASP C OD1 1 
ATOM   6434 O OD2 . ASP C 3 312 ? 131.974 103.492 127.826 1.00 137.14 -1 315 ASP C OD2 1 
ATOM   6435 N N   . THR C 3 313 ? 135.567 105.468 128.953 1.00 130.15 ?  316 THR C N   1 
ATOM   6436 C CA  . THR C 3 313 ? 135.702 106.832 129.445 1.00 130.14 ?  316 THR C CA  1 
ATOM   6437 C C   . THR C 3 313 ? 136.980 107.070 130.239 1.00 130.55 ?  316 THR C C   1 
ATOM   6438 O O   . THR C 3 313 ? 137.168 108.173 130.759 1.00 131.05 ?  316 THR C O   1 
ATOM   6439 C CB  . THR C 3 313 ? 134.492 107.200 130.309 1.00 129.42 ?  316 THR C CB  1 
ATOM   6440 O OG1 . THR C 3 313 ? 134.668 108.515 130.848 1.00 131.16 ?  316 THR C OG1 1 
ATOM   6441 C CG2 . THR C 3 313 ? 134.335 106.212 131.448 1.00 126.39 ?  316 THR C CG2 1 
ATOM   6442 N N   . LYS C 3 314 ? 137.860 106.078 130.344 1.00 116.34 ?  317 LYS C N   1 
ATOM   6443 C CA  . LYS C 3 314 ? 139.063 106.218 131.150 1.00 113.02 ?  317 LYS C CA  1 
ATOM   6444 C C   . LYS C 3 314 ? 140.162 105.342 130.572 1.00 114.59 ?  317 LYS C C   1 
ATOM   6445 O O   . LYS C 3 314 ? 139.919 104.190 130.208 1.00 118.66 ?  317 LYS C O   1 
ATOM   6446 C CB  . LYS C 3 314 ? 138.787 105.842 132.609 1.00 117.07 ?  317 LYS C CB  1 
ATOM   6447 C CG  . LYS C 3 314 ? 140.012 105.458 133.411 1.00 116.46 ?  317 LYS C CG  1 
ATOM   6448 C CD  . LYS C 3 314 ? 139.615 104.743 134.686 1.00 111.28 ?  317 LYS C CD  1 
ATOM   6449 C CE  . LYS C 3 314 ? 138.397 105.389 135.314 1.00 109.93 ?  317 LYS C CE  1 
ATOM   6450 N NZ  . LYS C 3 314 ? 138.372 105.220 136.787 1.00 114.41 1  317 LYS C NZ  1 
ATOM   6451 N N   . GLU C 3 315 ? 141.367 105.893 130.498 1.00 106.27 ?  318 GLU C N   1 
ATOM   6452 C CA  . GLU C 3 315 ? 142.518 105.204 129.937 1.00 108.79 ?  318 GLU C CA  1 
ATOM   6453 C C   . GLU C 3 315 ? 143.556 104.967 131.024 1.00 107.23 ?  318 GLU C C   1 
ATOM   6454 O O   . GLU C 3 315 ? 143.771 105.824 131.885 1.00 113.94 ?  318 GLU C O   1 
ATOM   6455 C CB  . GLU C 3 315 ? 143.126 106.014 128.791 1.00 108.72 ?  318 GLU C CB  1 
ATOM   6456 C CG  . GLU C 3 315 ? 144.398 105.429 128.211 1.00 113.14 ?  318 GLU C CG  1 
ATOM   6457 C CD  . GLU C 3 315 ? 144.598 105.809 126.761 1.00 117.46 ?  318 GLU C CD  1 
ATOM   6458 O OE1 . GLU C 3 315 ? 143.727 106.512 126.208 1.00 115.37 ?  318 GLU C OE1 1 
ATOM   6459 O OE2 . GLU C 3 315 ? 145.626 105.410 126.175 1.00 114.46 -1 318 GLU C OE2 1 
ATOM   6460 N N   . ILE C 3 316 ? 144.192 103.800 130.988 1.00 86.75  ?  319 ILE C N   1 
ATOM   6461 C CA  . ILE C 3 316 ? 145.232 103.434 131.941 1.00 89.73  ?  319 ILE C CA  1 
ATOM   6462 C C   . ILE C 3 316 ? 146.563 103.430 131.206 1.00 99.16  ?  319 ILE C C   1 
ATOM   6463 O O   . ILE C 3 316 ? 146.727 102.720 130.207 1.00 104.97 ?  319 ILE C O   1 
ATOM   6464 C CB  . ILE C 3 316 ? 144.957 102.070 132.589 1.00 83.23  ?  319 ILE C CB  1 
ATOM   6465 C CG1 . ILE C 3 316 ? 143.843 102.190 133.623 1.00 91.00  ?  319 ILE C CG1 1 
ATOM   6466 C CG2 . ILE C 3 316 ? 146.210 101.525 133.240 1.00 81.14  ?  319 ILE C CG2 1 
ATOM   6467 C CD1 . ILE C 3 316 ? 143.139 100.897 133.892 1.00 91.94  ?  319 ILE C CD1 1 
ATOM   6468 N N   . TYR C 3 317 ? 147.511 104.220 131.697 1.00 87.97  ?  320 TYR C N   1 
ATOM   6469 C CA  . TYR C 3 317 ? 148.854 104.283 131.139 1.00 78.97  ?  320 TYR C CA  1 
ATOM   6470 C C   . TYR C 3 317 ? 149.794 103.524 132.063 1.00 83.43  ?  320 TYR C C   1 
ATOM   6471 O O   . TYR C 3 317 ? 149.868 103.825 133.257 1.00 95.74  ?  320 TYR C O   1 
ATOM   6472 C CB  . TYR C 3 317 ? 149.315 105.730 130.982 1.00 83.07  ?  320 TYR C CB  1 
ATOM   6473 C CG  . TYR C 3 317 ? 148.311 106.633 130.309 1.00 86.28  ?  320 TYR C CG  1 
ATOM   6474 C CD1 . TYR C 3 317 ? 147.350 107.303 131.046 1.00 84.36  ?  320 TYR C CD1 1 
ATOM   6475 C CD2 . TYR C 3 317 ? 148.334 106.825 128.938 1.00 84.72  ?  320 TYR C CD2 1 
ATOM   6476 C CE1 . TYR C 3 317 ? 146.437 108.128 130.437 1.00 87.28  ?  320 TYR C CE1 1 
ATOM   6477 C CE2 . TYR C 3 317 ? 147.424 107.650 128.321 1.00 82.32  ?  320 TYR C CE2 1 
ATOM   6478 C CZ  . TYR C 3 317 ? 146.478 108.298 129.074 1.00 89.36  ?  320 TYR C CZ  1 
ATOM   6479 O OH  . TYR C 3 317 ? 145.568 109.123 128.462 1.00 96.11  ?  320 TYR C OH  1 
ATOM   6480 N N   . THR C 3 318 ? 150.510 102.549 131.515 1.00 86.85  ?  321 THR C N   1 
ATOM   6481 C CA  . THR C 3 318 ? 151.398 101.704 132.296 1.00 89.08  ?  321 THR C CA  1 
ATOM   6482 C C   . THR C 3 318 ? 152.845 101.952 131.901 1.00 89.43  ?  321 THR C C   1 
ATOM   6483 O O   . THR C 3 318 ? 153.161 102.090 130.717 1.00 95.27  ?  321 THR C O   1 
ATOM   6484 C CB  . THR C 3 318 ? 151.061 100.227 132.113 1.00 90.53  ?  321 THR C CB  1 
ATOM   6485 O OG1 . THR C 3 318 ? 149.643 100.074 131.990 1.00 93.58  ?  321 THR C OG1 1 
ATOM   6486 C CG2 . THR C 3 318 ? 151.545 99.431  133.305 1.00 86.81  ?  321 THR C CG2 1 
ATOM   6487 N N   . HIS C 3 319 ? 153.719 102.001 132.901 1.00 100.08 ?  322 HIS C N   1 
ATOM   6488 C CA  . HIS C 3 319 ? 155.139 102.245 132.686 1.00 103.11 ?  322 HIS C CA  1 
ATOM   6489 C C   . HIS C 3 319 ? 155.927 101.355 133.630 1.00 107.15 ?  322 HIS C C   1 
ATOM   6490 O O   . HIS C 3 319 ? 155.779 101.463 134.849 1.00 115.93 ?  322 HIS C O   1 
ATOM   6491 C CB  . HIS C 3 319 ? 155.480 103.718 132.922 1.00 108.59 ?  322 HIS C CB  1 
ATOM   6492 C CG  . HIS C 3 319 ? 156.889 104.078 132.572 1.00 113.89 ?  322 HIS C CG  1 
ATOM   6493 N ND1 . HIS C 3 319 ? 157.399 103.939 131.299 1.00 110.94 ?  322 HIS C ND1 1 
ATOM   6494 C CD2 . HIS C 3 319 ? 157.894 104.580 133.327 1.00 111.30 ?  322 HIS C CD2 1 
ATOM   6495 C CE1 . HIS C 3 319 ? 158.658 104.336 131.286 1.00 111.27 ?  322 HIS C CE1 1 
ATOM   6496 N NE2 . HIS C 3 319 ? 158.984 104.728 132.504 1.00 113.49 ?  322 HIS C NE2 1 
ATOM   6497 N N   . PHE C 3 320 ? 156.759 100.476 133.072 1.00 114.74 ?  323 PHE C N   1 
ATOM   6498 C CA  . PHE C 3 320 ? 157.600 99.593  133.878 1.00 116.52 ?  323 PHE C CA  1 
ATOM   6499 C C   . PHE C 3 320 ? 158.800 100.397 134.365 1.00 119.85 ?  323 PHE C C   1 
ATOM   6500 O O   . PHE C 3 320 ? 159.899 100.350 133.808 1.00 123.58 ?  323 PHE C O   1 
ATOM   6501 C CB  . PHE C 3 320 ? 158.022 98.371  133.079 1.00 116.62 ?  323 PHE C CB  1 
ATOM   6502 C CG  . PHE C 3 320 ? 156.916 97.387  132.860 1.00 119.53 ?  323 PHE C CG  1 
ATOM   6503 C CD1 . PHE C 3 320 ? 156.052 97.526  131.790 1.00 119.52 ?  323 PHE C CD1 1 
ATOM   6504 C CD2 . PHE C 3 320 ? 156.735 96.329  133.726 1.00 116.24 ?  323 PHE C CD2 1 
ATOM   6505 C CE1 . PHE C 3 320 ? 155.034 96.623  131.586 1.00 117.06 ?  323 PHE C CE1 1 
ATOM   6506 C CE2 . PHE C 3 320 ? 155.720 95.426  133.528 1.00 115.84 ?  323 PHE C CE2 1 
ATOM   6507 C CZ  . PHE C 3 320 ? 154.867 95.572  132.457 1.00 117.75 ?  323 PHE C CZ  1 
ATOM   6508 N N   . THR C 3 321 ? 158.574 101.150 135.434 1.00 124.62 ?  324 THR C N   1 
ATOM   6509 C CA  . THR C 3 321 ? 159.554 102.095 135.933 1.00 122.91 ?  324 THR C CA  1 
ATOM   6510 C C   . THR C 3 321 ? 160.646 101.390 136.734 1.00 124.11 ?  324 THR C C   1 
ATOM   6511 O O   . THR C 3 321 ? 160.551 100.208 137.073 1.00 126.90 ?  324 THR C O   1 
ATOM   6512 C CB  . THR C 3 321 ? 158.874 103.156 136.791 1.00 122.05 ?  324 THR C CB  1 
ATOM   6513 O OG1 . THR C 3 321 ? 159.755 104.271 136.959 1.00 131.15 ?  324 THR C OG1 1 
ATOM   6514 C CG2 . THR C 3 321 ? 158.530 102.591 138.142 1.00 118.74 ?  324 THR C CG2 1 
ATOM   6515 N N   . CYS C 3 322 ? 161.698 102.141 137.027 1.00 151.46 ?  325 CYS C N   1 
ATOM   6516 C CA  . CYS C 3 322 ? 162.828 101.698 137.840 1.00 154.72 ?  325 CYS C CA  1 
ATOM   6517 C C   . CYS C 3 322 ? 163.620 102.944 138.224 1.00 155.87 ?  325 CYS C C   1 
ATOM   6518 O O   . CYS C 3 322 ? 163.162 104.074 138.014 1.00 154.95 ?  325 CYS C O   1 
ATOM   6519 C CB  . CYS C 3 322 ? 163.690 100.677 137.095 1.00 155.11 ?  325 CYS C CB  1 
ATOM   6520 S SG  . CYS C 3 322 ? 165.234 100.250 137.931 1.00 155.15 ?  325 CYS C SG  1 
ATOM   6521 N N   . SER C 3 323 ? 164.807 102.741 138.799 1.00 158.04 ?  326 SER C N   1 
ATOM   6522 C CA  . SER C 3 323 ? 165.706 103.861 139.056 1.00 157.07 ?  326 SER C CA  1 
ATOM   6523 C C   . SER C 3 323 ? 166.018 104.604 137.762 1.00 159.16 ?  326 SER C C   1 
ATOM   6524 O O   . SER C 3 323 ? 165.673 105.782 137.608 1.00 157.45 ?  326 SER C O   1 
ATOM   6525 C CB  . SER C 3 323 ? 166.991 103.360 139.718 1.00 153.93 ?  326 SER C CB  1 
ATOM   6526 O OG  . SER C 3 323 ? 167.593 102.334 138.948 1.00 153.95 ?  326 SER C OG  1 
ATOM   6527 N N   . THR C 3 324 ? 166.653 103.912 136.812 1.00 160.11 ?  327 THR C N   1 
ATOM   6528 C CA  . THR C 3 324 ? 166.896 104.383 135.450 1.00 160.49 ?  327 THR C CA  1 
ATOM   6529 C C   . THR C 3 324 ? 167.271 105.858 135.374 1.00 158.59 ?  327 THR C C   1 
ATOM   6530 O O   . THR C 3 324 ? 168.159 106.324 136.095 1.00 154.97 ?  327 THR C O   1 
ATOM   6531 C CB  . THR C 3 324 ? 165.665 104.121 134.572 1.00 159.40 ?  327 THR C CB  1 
ATOM   6532 O OG1 . THR C 3 324 ? 164.474 104.498 135.274 1.00 156.34 ?  327 THR C OG1 1 
ATOM   6533 C CG2 . THR C 3 324 ? 165.579 102.648 134.199 1.00 154.30 ?  327 THR C CG2 1 
ATOM   6534 N N   . ASP C 3 325 ? 166.590 106.597 134.500 1.00 156.33 ?  328 ASP C N   1 
ATOM   6535 C CA  . ASP C 3 325 ? 166.809 108.027 134.335 1.00 155.73 ?  328 ASP C CA  1 
ATOM   6536 C C   . ASP C 3 325 ? 165.485 108.753 134.524 1.00 155.05 ?  328 ASP C C   1 
ATOM   6537 O O   . ASP C 3 325 ? 164.502 108.144 134.957 1.00 151.07 ?  328 ASP C O   1 
ATOM   6538 C CB  . ASP C 3 325 ? 167.406 108.331 132.960 1.00 154.41 ?  328 ASP C CB  1 
ATOM   6539 C CG  . ASP C 3 325 ? 168.257 109.586 132.958 1.00 155.55 ?  328 ASP C CG  1 
ATOM   6540 O OD1 . ASP C 3 325 ? 168.080 110.426 133.865 1.00 155.44 ?  328 ASP C OD1 1 
ATOM   6541 O OD2 . ASP C 3 325 ? 169.101 109.732 132.050 1.00 155.81 -1 328 ASP C OD2 1 
ATOM   6542 N N   . THR C 3 326 ? 165.436 110.043 134.205 1.00 149.66 ?  329 THR C N   1 
ATOM   6543 C CA  . THR C 3 326 ? 164.201 110.811 134.366 1.00 149.07 ?  329 THR C CA  1 
ATOM   6544 C C   . THR C 3 326 ? 163.206 110.498 133.253 1.00 148.34 ?  329 THR C C   1 
ATOM   6545 O O   . THR C 3 326 ? 162.701 111.385 132.567 1.00 147.23 ?  329 THR C O   1 
ATOM   6546 C CB  . THR C 3 326 ? 164.511 112.302 134.416 1.00 148.54 ?  329 THR C CB  1 
ATOM   6547 O OG1 . THR C 3 326 ? 164.510 112.837 133.086 1.00 146.78 ?  329 THR C OG1 1 
ATOM   6548 C CG2 . THR C 3 326 ? 165.869 112.545 135.057 1.00 146.63 ?  329 THR C CG2 1 
ATOM   6549 N N   . LYS C 3 327 ? 162.918 109.210 133.075 1.00 133.40 ?  330 LYS C N   1 
ATOM   6550 C CA  . LYS C 3 327 ? 161.907 108.768 132.129 1.00 129.38 ?  330 LYS C CA  1 
ATOM   6551 C C   . LYS C 3 327 ? 160.522 108.698 132.749 1.00 132.37 ?  330 LYS C C   1 
ATOM   6552 O O   . LYS C 3 327 ? 159.528 108.804 132.024 1.00 135.12 ?  330 LYS C O   1 
ATOM   6553 C CB  . LYS C 3 327 ? 162.276 107.394 131.565 1.00 129.90 ?  330 LYS C CB  1 
ATOM   6554 C CG  . LYS C 3 327 ? 163.768 107.173 131.404 1.00 132.51 ?  330 LYS C CG  1 
ATOM   6555 C CD  . LYS C 3 327 ? 164.261 107.706 130.074 1.00 132.40 ?  330 LYS C CD  1 
ATOM   6556 C CE  . LYS C 3 327 ? 163.598 106.976 128.920 1.00 130.97 ?  330 LYS C CE  1 
ATOM   6557 N NZ  . LYS C 3 327 ? 163.690 105.499 129.082 1.00 129.16 1  330 LYS C NZ  1 
ATOM   6558 N N   . ASN C 3 328 ? 160.437 108.513 134.067 1.00 121.12 ?  331 ASN C N   1 
ATOM   6559 C CA  . ASN C 3 328 ? 159.140 108.503 134.731 1.00 116.89 ?  331 ASN C CA  1 
ATOM   6560 C C   . ASN C 3 328 ? 158.463 109.861 134.638 1.00 119.60 ?  331 ASN C C   1 
ATOM   6561 O O   . ASN C 3 328 ? 157.254 109.942 134.395 1.00 122.94 ?  331 ASN C O   1 
ATOM   6562 C CB  . ASN C 3 328 ? 159.305 108.087 136.189 1.00 119.04 ?  331 ASN C CB  1 
ATOM   6563 C CG  . ASN C 3 328 ? 160.421 107.092 136.381 1.00 124.54 ?  331 ASN C CG  1 
ATOM   6564 O OD1 . ASN C 3 328 ? 160.516 106.105 135.654 1.00 126.46 ?  331 ASN C OD1 1 
ATOM   6565 N ND2 . ASN C 3 328 ? 161.277 107.343 137.361 1.00 126.45 ?  331 ASN C ND2 1 
ATOM   6566 N N   . VAL C 3 329 ? 159.224 110.939 134.830 1.00 111.92 ?  332 VAL C N   1 
ATOM   6567 C CA  . VAL C 3 329 ? 158.648 112.274 134.726 1.00 110.34 ?  332 VAL C CA  1 
ATOM   6568 C C   . VAL C 3 329 ? 158.187 112.542 133.301 1.00 112.09 ?  332 VAL C C   1 
ATOM   6569 O O   . VAL C 3 329 ? 157.135 113.151 133.081 1.00 111.11 ?  332 VAL C O   1 
ATOM   6570 C CB  . VAL C 3 329 ? 159.653 113.333 135.205 1.00 107.10 ?  332 VAL C CB  1 
ATOM   6571 C CG1 . VAL C 3 329 ? 158.923 114.590 135.627 1.00 105.60 ?  332 VAL C CG1 1 
ATOM   6572 C CG2 . VAL C 3 329 ? 160.487 112.790 136.347 1.00 112.69 ?  332 VAL C CG2 1 
ATOM   6573 N N   . GLN C 3 330 ? 158.961 112.093 132.312 1.00 108.78 ?  333 GLN C N   1 
ATOM   6574 C CA  . GLN C 3 330 ? 158.548 112.262 130.923 1.00 107.02 ?  333 GLN C CA  1 
ATOM   6575 C C   . GLN C 3 330 ? 157.281 111.474 130.623 1.00 108.38 ?  333 GLN C C   1 
ATOM   6576 O O   . GLN C 3 330 ? 156.392 111.961 129.914 1.00 112.88 ?  333 GLN C O   1 
ATOM   6577 C CB  . GLN C 3 330 ? 159.675 111.842 129.982 1.00 107.39 ?  333 GLN C CB  1 
ATOM   6578 C CG  . GLN C 3 330 ? 159.360 112.076 128.518 1.00 109.94 ?  333 GLN C CG  1 
ATOM   6579 C CD  . GLN C 3 330 ? 159.298 113.546 128.171 1.00 115.88 ?  333 GLN C CD  1 
ATOM   6580 O OE1 . GLN C 3 330 ? 160.064 114.350 128.698 1.00 116.98 ?  333 GLN C OE1 1 
ATOM   6581 N NE2 . GLN C 3 330 ? 158.376 113.908 127.289 1.00 107.91 ?  333 GLN C NE2 1 
ATOM   6582 N N   . PHE C 3 331 ? 157.182 110.250 131.142 1.00 96.58  ?  334 PHE C N   1 
ATOM   6583 C CA  . PHE C 3 331 ? 155.973 109.459 130.938 1.00 92.71  ?  334 PHE C CA  1 
ATOM   6584 C C   . PHE C 3 331 ? 154.766 110.127 131.579 1.00 97.01  ?  334 PHE C C   1 
ATOM   6585 O O   . PHE C 3 331 ? 153.680 110.168 130.987 1.00 106.67 ?  334 PHE C O   1 
ATOM   6586 C CB  . PHE C 3 331 ? 156.164 108.054 131.500 1.00 90.64  ?  334 PHE C CB  1 
ATOM   6587 C CG  . PHE C 3 331 ? 155.016 107.134 131.222 1.00 96.79  ?  334 PHE C CG  1 
ATOM   6588 C CD1 . PHE C 3 331 ? 154.972 106.396 130.057 1.00 98.54  ?  334 PHE C CD1 1 
ATOM   6589 C CD2 . PHE C 3 331 ? 153.976 107.013 132.124 1.00 97.89  ?  334 PHE C CD2 1 
ATOM   6590 C CE1 . PHE C 3 331 ? 153.917 105.553 129.798 1.00 100.13 ?  334 PHE C CE1 1 
ATOM   6591 C CE2 . PHE C 3 331 ? 152.921 106.175 131.869 1.00 98.32  ?  334 PHE C CE2 1 
ATOM   6592 C CZ  . PHE C 3 331 ? 152.891 105.443 130.705 1.00 102.66 ?  334 PHE C CZ  1 
ATOM   6593 N N   . VAL C 3 332 ? 154.934 110.650 132.793 1.00 85.07  ?  335 VAL C N   1 
ATOM   6594 C CA  . VAL C 3 332 ? 153.839 111.346 133.458 1.00 80.85  ?  335 VAL C CA  1 
ATOM   6595 C C   . VAL C 3 332 ? 153.444 112.581 132.665 1.00 88.88  ?  335 VAL C C   1 
ATOM   6596 O O   . VAL C 3 332 ? 152.259 112.898 132.535 1.00 91.27  ?  335 VAL C O   1 
ATOM   6597 C CB  . VAL C 3 332 ? 154.225 111.697 134.906 1.00 82.03  ?  335 VAL C CB  1 
ATOM   6598 C CG1 . VAL C 3 332 ? 153.208 112.642 135.512 1.00 82.71  ?  335 VAL C CG1 1 
ATOM   6599 C CG2 . VAL C 3 332 ? 154.332 110.442 135.739 1.00 87.12  ?  335 VAL C CG2 1 
ATOM   6600 N N   . PHE C 3 333 ? 154.429 113.294 132.112 1.00 100.17 ?  336 PHE C N   1 
ATOM   6601 C CA  . PHE C 3 333 ? 154.130 114.477 131.315 1.00 95.06  ?  336 PHE C CA  1 
ATOM   6602 C C   . PHE C 3 333 ? 153.360 114.117 130.052 1.00 95.91  ?  336 PHE C C   1 
ATOM   6603 O O   . PHE C 3 333 ? 152.416 114.816 129.678 1.00 99.75  ?  336 PHE C O   1 
ATOM   6604 C CB  . PHE C 3 333 ? 155.419 115.215 130.963 1.00 94.99  ?  336 PHE C CB  1 
ATOM   6605 C CG  . PHE C 3 333 ? 155.201 116.455 130.150 1.00 99.70  ?  336 PHE C CG  1 
ATOM   6606 C CD1 . PHE C 3 333 ? 154.715 117.606 130.738 1.00 101.54 ?  336 PHE C CD1 1 
ATOM   6607 C CD2 . PHE C 3 333 ? 155.476 116.469 128.797 1.00 97.77  ?  336 PHE C CD2 1 
ATOM   6608 C CE1 . PHE C 3 333 ? 154.510 118.743 129.994 1.00 95.74  ?  336 PHE C CE1 1 
ATOM   6609 C CE2 . PHE C 3 333 ? 155.270 117.604 128.050 1.00 99.39  ?  336 PHE C CE2 1 
ATOM   6610 C CZ  . PHE C 3 333 ? 154.787 118.742 128.650 1.00 95.13  ?  336 PHE C CZ  1 
ATOM   6611 N N   . ASP C 3 334 ? 153.747 113.031 129.382 1.00 94.71  ?  337 ASP C N   1 
ATOM   6612 C CA  . ASP C 3 334 ? 153.029 112.607 128.184 1.00 94.95  ?  337 ASP C CA  1 
ATOM   6613 C C   . ASP C 3 334 ? 151.597 112.203 128.513 1.00 98.20  ?  337 ASP C C   1 
ATOM   6614 O O   . ASP C 3 334 ? 150.650 112.587 127.813 1.00 107.61 ?  337 ASP C O   1 
ATOM   6615 C CB  . ASP C 3 334 ? 153.770 111.454 127.512 1.00 98.15  ?  337 ASP C CB  1 
ATOM   6616 C CG  . ASP C 3 334 ? 155.170 111.834 127.086 1.00 109.01 ?  337 ASP C CG  1 
ATOM   6617 O OD1 . ASP C 3 334 ? 155.494 113.037 127.116 1.00 111.97 ?  337 ASP C OD1 1 
ATOM   6618 O OD2 . ASP C 3 334 ? 155.948 110.929 126.721 1.00 105.63 -1 337 ASP C OD2 1 
ATOM   6619 N N   . ALA C 3 335 ? 151.418 111.427 129.584 1.00 82.99  ?  338 ALA C N   1 
ATOM   6620 C CA  . ALA C 3 335 ? 150.075 111.017 129.977 1.00 77.12  ?  338 ALA C CA  1 
ATOM   6621 C C   . ALA C 3 335 ? 149.223 112.217 130.367 1.00 86.90  ?  338 ALA C C   1 
ATOM   6622 O O   . ALA C 3 335 ? 148.038 112.290 130.019 1.00 90.99  ?  338 ALA C O   1 
ATOM   6623 C CB  . ALA C 3 335 ? 150.152 110.016 131.126 1.00 81.40  ?  338 ALA C CB  1 
ATOM   6624 N N   . VAL C 3 336 ? 149.812 113.172 131.086 1.00 88.78  ?  339 VAL C N   1 
ATOM   6625 C CA  . VAL C 3 336 ? 149.078 114.358 131.504 1.00 84.09  ?  339 VAL C CA  1 
ATOM   6626 C C   . VAL C 3 336 ? 148.721 115.218 130.300 1.00 95.78  ?  339 VAL C C   1 
ATOM   6627 O O   . VAL C 3 336 ? 147.638 115.807 130.246 1.00 98.09  ?  339 VAL C O   1 
ATOM   6628 C CB  . VAL C 3 336 ? 149.897 115.135 132.549 1.00 83.30  ?  339 VAL C CB  1 
ATOM   6629 C CG1 . VAL C 3 336 ? 149.536 116.604 132.540 1.00 93.64  ?  339 VAL C CG1 1 
ATOM   6630 C CG2 . VAL C 3 336 ? 149.675 114.541 133.922 1.00 88.69  ?  339 VAL C CG2 1 
ATOM   6631 N N   . THR C 3 337 ? 149.616 115.302 129.315 1.00 96.26  ?  340 THR C N   1 
ATOM   6632 C CA  . THR C 3 337 ? 149.301 116.030 128.091 1.00 84.94  ?  340 THR C CA  1 
ATOM   6633 C C   . THR C 3 337 ? 148.141 115.379 127.352 1.00 83.57  ?  340 THR C C   1 
ATOM   6634 O O   . THR C 3 337 ? 147.256 116.073 126.843 1.00 96.92  ?  340 THR C O   1 
ATOM   6635 C CB  . THR C 3 337 ? 150.532 116.107 127.194 1.00 88.16  ?  340 THR C CB  1 
ATOM   6636 O OG1 . THR C 3 337 ? 151.612 116.699 127.922 1.00 96.18  ?  340 THR C OG1 1 
ATOM   6637 C CG2 . THR C 3 337 ? 150.243 116.951 125.973 1.00 91.25  ?  340 THR C CG2 1 
ATOM   6638 N N   . ASP C 3 338 ? 148.124 114.047 127.289 1.00 82.19  ?  341 ASP C N   1 
ATOM   6639 C CA  . ASP C 3 338 ? 146.989 113.358 126.680 1.00 75.57  ?  341 ASP C CA  1 
ATOM   6640 C C   . ASP C 3 338 ? 145.697 113.667 127.425 1.00 81.03  ?  341 ASP C C   1 
ATOM   6641 O O   . ASP C 3 338 ? 144.667 113.972 126.811 1.00 96.19  ?  341 ASP C O   1 
ATOM   6642 C CB  . ASP C 3 338 ? 147.239 111.853 126.655 1.00 85.62  ?  341 ASP C CB  1 
ATOM   6643 C CG  . ASP C 3 338 ? 148.042 111.418 125.456 1.00 98.62  ?  341 ASP C CG  1 
ATOM   6644 O OD1 . ASP C 3 338 ? 149.032 112.102 125.127 1.00 98.81  ?  341 ASP C OD1 1 
ATOM   6645 O OD2 . ASP C 3 338 ? 147.688 110.390 124.844 1.00 99.17  -1 341 ASP C OD2 1 
ATOM   6646 N N   . VAL C 3 339 ? 145.737 113.604 128.757 1.00 84.88  ?  342 VAL C N   1 
ATOM   6647 C CA  . VAL C 3 339 ? 144.539 113.863 129.553 1.00 88.94  ?  342 VAL C CA  1 
ATOM   6648 C C   . VAL C 3 339 ? 144.060 115.294 129.347 1.00 88.02  ?  342 VAL C C   1 
ATOM   6649 O O   . VAL C 3 339 ? 142.857 115.553 129.236 1.00 92.08  ?  342 VAL C O   1 
ATOM   6650 C CB  . VAL C 3 339 ? 144.812 113.566 131.039 1.00 93.16  ?  342 VAL C CB  1 
ATOM   6651 C CG1 . VAL C 3 339 ? 143.635 113.993 131.892 1.00 87.08  ?  342 VAL C CG1 1 
ATOM   6652 C CG2 . VAL C 3 339 ? 145.106 112.095 131.237 1.00 84.87  ?  342 VAL C CG2 1 
ATOM   6653 N N   . ILE C 3 340 ? 144.993 116.243 129.293 1.00 85.07  ?  343 ILE C N   1 
ATOM   6654 C CA  . ILE C 3 340 ? 144.636 117.645 129.119 1.00 80.01  ?  343 ILE C CA  1 
ATOM   6655 C C   . ILE C 3 340 ? 144.065 117.884 127.729 1.00 88.91  ?  343 ILE C C   1 
ATOM   6656 O O   . ILE C 3 340 ? 143.148 118.691 127.554 1.00 98.27  ?  343 ILE C O   1 
ATOM   6657 C CB  . ILE C 3 340 ? 145.856 118.537 129.406 1.00 82.68  ?  343 ILE C CB  1 
ATOM   6658 C CG1 . ILE C 3 340 ? 146.144 118.559 130.906 1.00 90.29  ?  343 ILE C CG1 1 
ATOM   6659 C CG2 . ILE C 3 340 ? 145.625 119.943 128.901 1.00 85.83  ?  343 ILE C CG2 1 
ATOM   6660 C CD1 . ILE C 3 340 ? 147.338 119.391 131.289 1.00 87.11  ?  343 ILE C CD1 1 
ATOM   6661 N N   . ILE C 3 341 ? 144.591 117.192 126.718 1.00 90.90  ?  344 ILE C N   1 
ATOM   6662 C CA  . ILE C 3 341 ? 144.026 117.303 125.377 1.00 77.19  ?  344 ILE C CA  1 
ATOM   6663 C C   . ILE C 3 341 ? 142.594 116.786 125.363 1.00 85.84  ?  344 ILE C C   1 
ATOM   6664 O O   . ILE C 3 341 ? 141.702 117.403 124.767 1.00 98.50  ?  344 ILE C O   1 
ATOM   6665 C CB  . ILE C 3 341 ? 144.913 116.563 124.361 1.00 73.11  ?  344 ILE C CB  1 
ATOM   6666 C CG1 . ILE C 3 341 ? 146.165 117.384 124.068 1.00 75.95  ?  344 ILE C CG1 1 
ATOM   6667 C CG2 . ILE C 3 341 ? 144.158 116.305 123.081 1.00 80.37  ?  344 ILE C CG2 1 
ATOM   6668 C CD1 . ILE C 3 341 ? 147.011 116.832 122.963 1.00 82.18  ?  344 ILE C CD1 1 
ATOM   6669 N N   . LYS C 3 342 ? 142.347 115.654 126.028 1.00 88.88  ?  345 LYS C N   1 
ATOM   6670 C CA  . LYS C 3 342 ? 140.978 115.149 126.122 1.00 90.58  ?  345 LYS C CA  1 
ATOM   6671 C C   . LYS C 3 342 ? 140.070 116.143 126.837 1.00 90.56  ?  345 LYS C C   1 
ATOM   6672 O O   . LYS C 3 342 ? 138.930 116.369 126.417 1.00 97.79  ?  345 LYS C O   1 
ATOM   6673 C CB  . LYS C 3 342 ? 140.945 113.803 126.844 1.00 98.16  ?  345 LYS C CB  1 
ATOM   6674 C CG  . LYS C 3 342 ? 141.939 112.780 126.344 1.00 97.94  ?  345 LYS C CG  1 
ATOM   6675 C CD  . LYS C 3 342 ? 141.439 112.044 125.129 1.00 100.85 ?  345 LYS C CD  1 
ATOM   6676 C CE  . LYS C 3 342 ? 142.600 111.497 124.325 1.00 102.84 ?  345 LYS C CE  1 
ATOM   6677 N NZ  . LYS C 3 342 ? 143.604 112.554 124.034 1.00 100.04 1  345 LYS C NZ  1 
ATOM   6678 N N   . ASN C 3 343 ? 140.556 116.739 127.927 1.00 92.11  ?  346 ASN C N   1 
ATOM   6679 C CA  . ASN C 3 343 ? 139.748 117.705 128.666 1.00 92.17  ?  346 ASN C CA  1 
ATOM   6680 C C   . ASN C 3 343 ? 139.442 118.933 127.821 1.00 100.11 ?  346 ASN C C   1 
ATOM   6681 O O   . ASN C 3 343 ? 138.320 119.452 127.847 1.00 106.07 ?  346 ASN C O   1 
ATOM   6682 C CB  . ASN C 3 343 ? 140.464 118.112 129.951 1.00 94.87  ?  346 ASN C CB  1 
ATOM   6683 C CG  . ASN C 3 343 ? 140.609 116.967 130.923 1.00 101.66 ?  346 ASN C CG  1 
ATOM   6684 O OD1 . ASN C 3 343 ? 140.287 115.824 130.605 1.00 104.14 ?  346 ASN C OD1 1 
ATOM   6685 N ND2 . ASN C 3 343 ? 141.100 117.266 132.118 1.00 101.35 ?  346 ASN C ND2 1 
ATOM   6686 N N   . ASN C 3 344 ? 140.434 119.417 127.074 1.00 101.38 ?  347 ASN C N   1 
ATOM   6687 C CA  . ASN C 3 344 ? 140.221 120.559 126.194 1.00 94.99  ?  347 ASN C CA  1 
ATOM   6688 C C   . ASN C 3 344 ? 139.194 120.233 125.121 1.00 96.58  ?  347 ASN C C   1 
ATOM   6689 O O   . ASN C 3 344 ? 138.316 121.049 124.825 1.00 101.64 ?  347 ASN C O   1 
ATOM   6690 C CB  . ASN C 3 344 ? 141.543 120.983 125.560 1.00 91.55  ?  347 ASN C CB  1 
ATOM   6691 C CG  . ASN C 3 344 ? 142.444 121.707 126.529 1.00 96.06  ?  347 ASN C CG  1 
ATOM   6692 O OD1 . ASN C 3 344 ? 142.012 122.121 127.601 1.00 102.92 ?  347 ASN C OD1 1 
ATOM   6693 N ND2 . ASN C 3 344 ? 143.706 121.866 126.158 1.00 88.44  ?  347 ASN C ND2 1 
ATOM   6694 N N   . LEU C 3 345 ? 139.281 119.037 124.537 1.00 92.55  ?  348 LEU C N   1 
ATOM   6695 C CA  . LEU C 3 345 ? 138.288 118.625 123.552 1.00 90.41  ?  348 LEU C CA  1 
ATOM   6696 C C   . LEU C 3 345 ? 136.901 118.540 124.172 1.00 99.59  ?  348 LEU C C   1 
ATOM   6697 O O   . LEU C 3 345 ? 135.900 118.851 123.517 1.00 109.46 ?  348 LEU C O   1 
ATOM   6698 C CB  . LEU C 3 345 ? 138.690 117.289 122.935 1.00 92.27  ?  348 LEU C CB  1 
ATOM   6699 C CG  . LEU C 3 345 ? 139.859 117.383 121.960 1.00 94.05  ?  348 LEU C CG  1 
ATOM   6700 C CD1 . LEU C 3 345 ? 140.031 116.088 121.197 1.00 93.55  ?  348 LEU C CD1 1 
ATOM   6701 C CD2 . LEU C 3 345 ? 139.636 118.539 121.011 1.00 94.10  ?  348 LEU C CD2 1 
ATOM   6702 N N   . LYS C 3 346 ? 136.818 118.108 125.431 1.00 112.02 ?  349 LYS C N   1 
ATOM   6703 C CA  . LYS C 3 346 ? 135.537 118.127 126.130 1.00 109.12 ?  349 LYS C CA  1 
ATOM   6704 C C   . LYS C 3 346 ? 135.017 119.550 126.286 1.00 110.21 ?  349 LYS C C   1 
ATOM   6705 O O   . LYS C 3 346 ? 133.816 119.800 126.135 1.00 114.46 ?  349 LYS C O   1 
ATOM   6706 C CB  . LYS C 3 346 ? 135.667 117.464 127.501 1.00 112.30 ?  349 LYS C CB  1 
ATOM   6707 C CG  . LYS C 3 346 ? 135.026 116.093 127.605 1.00 113.80 ?  349 LYS C CG  1 
ATOM   6708 C CD  . LYS C 3 346 ? 136.063 114.989 127.540 1.00 114.63 ?  349 LYS C CD  1 
ATOM   6709 C CE  . LYS C 3 346 ? 136.868 114.908 128.828 1.00 112.60 ?  349 LYS C CE  1 
ATOM   6710 N NZ  . LYS C 3 346 ? 137.772 113.725 128.847 1.00 112.02 1  349 LYS C NZ  1 
ATOM   6711 N N   . ASP C 3 347 ? 135.906 120.495 126.600 1.00 115.42 ?  350 ASP C N   1 
ATOM   6712 C CA  . ASP C 3 347 ? 135.474 121.865 126.862 1.00 120.02 ?  350 ASP C CA  1 
ATOM   6713 C C   . ASP C 3 347 ? 134.849 122.504 125.628 1.00 121.70 ?  350 ASP C C   1 
ATOM   6714 O O   . ASP C 3 347 ? 133.836 123.204 125.730 1.00 124.18 ?  350 ASP C O   1 
ATOM   6715 C CB  . ASP C 3 347 ? 136.651 122.700 127.359 1.00 120.56 ?  350 ASP C CB  1 
ATOM   6716 C CG  . ASP C 3 347 ? 136.779 122.682 128.865 1.00 123.71 ?  350 ASP C CG  1 
ATOM   6717 O OD1 . ASP C 3 347 ? 135.872 122.140 129.530 1.00 123.49 ?  350 ASP C OD1 1 
ATOM   6718 O OD2 . ASP C 3 347 ? 137.785 123.208 129.385 1.00 121.76 -1 350 ASP C OD2 1 
ATOM   6719 N N   . CYS C 3 348 ? 135.436 122.282 124.455 1.00 120.75 ?  351 CYS C N   1 
ATOM   6720 C CA  . CYS C 3 348 ? 134.869 122.794 123.215 1.00 120.62 ?  351 CYS C CA  1 
ATOM   6721 C C   . CYS C 3 348 ? 133.869 121.834 122.588 1.00 120.41 ?  351 CYS C C   1 
ATOM   6722 O O   . CYS C 3 348 ? 133.355 122.118 121.502 1.00 121.93 ?  351 CYS C O   1 
ATOM   6723 C CB  . CYS C 3 348 ? 135.980 123.131 122.216 1.00 120.94 ?  351 CYS C CB  1 
ATOM   6724 S SG  . CYS C 3 348 ? 137.276 121.903 122.057 1.00 121.43 ?  351 CYS C SG  1 
ATOM   6725 N N   . GLY C 3 349 ? 133.589 120.711 123.243 1.00 127.52 ?  352 GLY C N   1 
ATOM   6726 C CA  . GLY C 3 349 ? 132.478 119.858 122.877 1.00 129.12 ?  352 GLY C CA  1 
ATOM   6727 C C   . GLY C 3 349 ? 132.533 119.189 121.521 1.00 131.59 ?  352 GLY C C   1 
ATOM   6728 O O   . GLY C 3 349 ? 131.544 119.214 120.784 1.00 136.07 ?  352 GLY C O   1 
ATOM   6729 N N   . LEU C 3 350 ? 133.670 118.589 121.165 1.00 120.93 ?  353 LEU C N   1 
ATOM   6730 C CA  . LEU C 3 350 ? 133.716 117.725 119.994 1.00 124.14 ?  353 LEU C CA  1 
ATOM   6731 C C   . LEU C 3 350 ? 134.367 116.380 120.291 1.00 124.53 ?  353 LEU C C   1 
ATOM   6732 O O   . LEU C 3 350 ? 134.568 115.588 119.365 1.00 124.98 ?  353 LEU C O   1 
ATOM   6733 C CB  . LEU C 3 350 ? 134.444 118.395 118.823 1.00 122.61 ?  353 LEU C CB  1 
ATOM   6734 C CG  . LEU C 3 350 ? 135.960 118.547 118.897 1.00 120.25 ?  353 LEU C CG  1 
ATOM   6735 C CD1 . LEU C 3 350 ? 136.549 118.548 117.505 1.00 118.29 ?  353 LEU C CD1 1 
ATOM   6736 C CD2 . LEU C 3 350 ? 136.300 119.826 119.593 1.00 120.44 ?  353 LEU C CD2 1 
ATOM   6737 N N   . PHE C 3 351 ? 134.691 116.096 121.546 1.00 134.64 ?  354 PHE C N   1 
ATOM   6738 C CA  . PHE C 3 351 ? 135.301 114.820 121.890 1.00 136.66 ?  354 PHE C CA  1 
ATOM   6739 C C   . PHE C 3 351 ? 134.285 113.689 121.777 1.00 141.19 ?  354 PHE C C   1 
ATOM   6740 O O   . PHE C 3 351 ? 134.200 113.012 120.753 1.00 139.47 ?  354 PHE C O   1 
ATOM   6741 C CB  . PHE C 3 351 ? 135.884 114.859 123.302 1.00 131.68 ?  354 PHE C CB  1 
ATOM   6742 C CG  . PHE C 3 351 ? 136.671 113.634 123.659 1.00 135.39 ?  354 PHE C CG  1 
ATOM   6743 C CD1 . PHE C 3 351 ? 137.669 113.170 122.823 1.00 135.26 ?  354 PHE C CD1 1 
ATOM   6744 C CD2 . PHE C 3 351 ? 136.405 112.939 124.824 1.00 134.65 ?  354 PHE C CD2 1 
ATOM   6745 C CE1 . PHE C 3 351 ? 138.392 112.044 123.146 1.00 134.00 ?  354 PHE C CE1 1 
ATOM   6746 C CE2 . PHE C 3 351 ? 137.127 111.812 125.153 1.00 136.27 ?  354 PHE C CE2 1 
ATOM   6747 C CZ  . PHE C 3 351 ? 138.119 111.362 124.311 1.00 135.09 ?  354 PHE C CZ  1 
ATOM   6748 O OXT . PHE C 3 351 ? 133.521 113.430 122.706 1.00 141.83 -1 354 PHE C OXT 1 
ATOM   6749 N N   . SER D 4 1   ? 145.803 92.397  175.714 1.00 181.42 ?  8   SER G N   1 
ATOM   6750 C CA  . SER D 4 1   ? 144.871 92.091  176.792 1.00 182.81 ?  8   SER G CA  1 
ATOM   6751 C C   . SER D 4 1   ? 143.426 92.239  176.324 1.00 184.46 ?  8   SER G C   1 
ATOM   6752 O O   . SER D 4 1   ? 143.163 92.432  175.137 1.00 182.70 ?  8   SER G O   1 
ATOM   6753 C CB  . SER D 4 1   ? 145.130 92.995  177.999 1.00 181.07 ?  8   SER G CB  1 
ATOM   6754 O OG  . SER D 4 1   ? 144.040 92.968  178.903 1.00 180.17 ?  8   SER G OG  1 
ATOM   6755 N N   . ILE D 4 2   ? 142.491 92.147  177.268 1.00 181.88 ?  9   ILE G N   1 
ATOM   6756 C CA  . ILE D 4 2   ? 141.069 92.247  176.962 1.00 179.03 ?  9   ILE G CA  1 
ATOM   6757 C C   . ILE D 4 2   ? 140.447 93.412  177.719 1.00 179.06 ?  9   ILE G C   1 
ATOM   6758 O O   . ILE D 4 2   ? 139.262 93.379  178.067 1.00 177.69 ?  9   ILE G O   1 
ATOM   6759 C CB  . ILE D 4 2   ? 140.342 90.921  177.266 1.00 178.59 ?  9   ILE G CB  1 
ATOM   6760 C CG1 . ILE D 4 2   ? 140.883 90.244  178.537 1.00 178.93 ?  9   ILE G CG1 1 
ATOM   6761 C CG2 . ILE D 4 2   ? 140.438 89.979  176.075 1.00 177.65 ?  9   ILE G CG2 1 
ATOM   6762 C CD1 . ILE D 4 2   ? 140.720 91.020  179.834 1.00 176.81 ?  9   ILE G CD1 1 
ATOM   6763 N N   . ALA D 4 3   ? 141.246 94.448  177.983 1.00 178.66 ?  10  ALA G N   1 
ATOM   6764 C CA  . ALA D 4 3   ? 140.744 95.604  178.717 1.00 177.86 ?  10  ALA G CA  1 
ATOM   6765 C C   . ALA D 4 3   ? 139.668 96.356  177.947 1.00 177.87 ?  10  ALA G C   1 
ATOM   6766 O O   . ALA D 4 3   ? 138.892 97.099  178.558 1.00 176.26 ?  10  ALA G O   1 
ATOM   6767 C CB  . ALA D 4 3   ? 141.896 96.548  179.064 1.00 176.94 ?  10  ALA G CB  1 
ATOM   6768 N N   . GLN D 4 4   ? 139.606 96.188  176.624 1.00 178.32 ?  11  GLN G N   1 
ATOM   6769 C CA  . GLN D 4 4   ? 138.557 96.843  175.850 1.00 175.96 ?  11  GLN G CA  1 
ATOM   6770 C C   . GLN D 4 4   ? 137.180 96.314  176.232 1.00 176.12 ?  11  GLN G C   1 
ATOM   6771 O O   . GLN D 4 4   ? 136.213 97.080  176.311 1.00 175.25 ?  11  GLN G O   1 
ATOM   6772 C CB  . GLN D 4 4   ? 138.819 96.678  174.350 1.00 174.89 ?  11  GLN G CB  1 
ATOM   6773 C CG  . GLN D 4 4   ? 138.641 95.268  173.796 1.00 176.38 ?  11  GLN G CG  1 
ATOM   6774 C CD  . GLN D 4 4   ? 139.828 94.364  174.083 1.00 177.30 ?  11  GLN G CD  1 
ATOM   6775 O OE1 . GLN D 4 4   ? 140.944 94.835  174.299 1.00 175.74 ?  11  GLN G OE1 1 
ATOM   6776 N NE2 . GLN D 4 4   ? 139.590 93.057  174.078 1.00 174.89 ?  11  GLN G NE2 1 
ATOM   6777 N N   . ALA D 4 5   ? 137.071 95.008  176.486 1.00 172.32 ?  12  ALA G N   1 
ATOM   6778 C CA  . ALA D 4 5   ? 135.801 94.447  176.934 1.00 171.04 ?  12  ALA G CA  1 
ATOM   6779 C C   . ALA D 4 5   ? 135.413 94.986  178.306 1.00 172.74 ?  12  ALA G C   1 
ATOM   6780 O O   . ALA D 4 5   ? 134.239 95.288  178.552 1.00 173.78 ?  12  ALA G O   1 
ATOM   6781 C CB  . ALA D 4 5   ? 135.879 92.921  176.954 1.00 168.85 ?  12  ALA G CB  1 
ATOM   6782 N N   . ARG D 4 6   ? 136.386 95.113  179.212 1.00 168.83 ?  13  ARG G N   1 
ATOM   6783 C CA  . ARG D 4 6   ? 136.106 95.696  180.519 1.00 169.59 ?  13  ARG G CA  1 
ATOM   6784 C C   . ARG D 4 6   ? 135.623 97.133  180.387 1.00 169.32 ?  13  ARG G C   1 
ATOM   6785 O O   . ARG D 4 6   ? 134.660 97.536  181.050 1.00 167.76 ?  13  ARG G O   1 
ATOM   6786 C CB  . ARG D 4 6   ? 137.354 95.632  181.400 1.00 168.53 ?  13  ARG G CB  1 
ATOM   6787 C CG  . ARG D 4 6   ? 137.350 94.512  182.426 1.00 169.55 ?  13  ARG G CG  1 
ATOM   6788 C CD  . ARG D 4 6   ? 138.196 93.337  181.965 1.00 171.32 ?  13  ARG G CD  1 
ATOM   6789 N NE  . ARG D 4 6   ? 139.584 93.715  181.727 1.00 173.05 ?  13  ARG G NE  1 
ATOM   6790 C CZ  . ARG D 4 6   ? 140.561 93.581  182.613 1.00 171.64 ?  13  ARG G CZ  1 
ATOM   6791 N NH1 . ARG D 4 6   ? 140.338 93.082  183.818 1.00 170.01 1  13  ARG G NH1 1 
ATOM   6792 N NH2 . ARG D 4 6   ? 141.793 93.956  182.282 1.00 169.32 ?  13  ARG G NH2 1 
ATOM   6793 N N   . LYS D 4 7   ? 136.281 97.921  179.533 1.00 164.03 ?  14  LYS G N   1 
ATOM   6794 C CA  . LYS D 4 7   ? 135.868 99.304  179.325 1.00 162.95 ?  14  LYS G CA  1 
ATOM   6795 C C   . LYS D 4 7   ? 134.466 99.376  178.734 1.00 163.29 ?  14  LYS G C   1 
ATOM   6796 O O   . LYS D 4 7   ? 133.657 100.225 179.132 1.00 162.53 ?  14  LYS G O   1 
ATOM   6797 C CB  . LYS D 4 7   ? 136.871 100.016 178.418 1.00 162.53 ?  14  LYS G CB  1 
ATOM   6798 C CG  . LYS D 4 7   ? 136.641 101.508 178.285 1.00 163.98 ?  14  LYS G CG  1 
ATOM   6799 C CD  . LYS D 4 7   ? 137.026 102.241 179.557 1.00 163.72 ?  14  LYS G CD  1 
ATOM   6800 C CE  . LYS D 4 7   ? 136.819 103.739 179.409 1.00 164.50 ?  14  LYS G CE  1 
ATOM   6801 N NZ  . LYS D 4 7   ? 137.695 104.316 178.352 1.00 164.73 1  14  LYS G NZ  1 
ATOM   6802 N N   . LEU D 4 8   ? 134.162 98.491  177.783 1.00 158.05 ?  15  LEU G N   1 
ATOM   6803 C CA  . LEU D 4 8   ? 132.824 98.453  177.205 1.00 157.26 ?  15  LEU G CA  1 
ATOM   6804 C C   . LEU D 4 8   ? 131.781 98.113  178.258 1.00 157.31 ?  15  LEU G C   1 
ATOM   6805 O O   . LEU D 4 8   ? 130.690 98.691  178.268 1.00 157.91 ?  15  LEU G O   1 
ATOM   6806 C CB  . LEU D 4 8   ? 132.775 97.444  176.059 1.00 157.20 ?  15  LEU G CB  1 
ATOM   6807 C CG  . LEU D 4 8   ? 131.790 97.764  174.934 1.00 157.62 ?  15  LEU G CG  1 
ATOM   6808 C CD1 . LEU D 4 8   ? 132.105 99.116  174.320 1.00 156.70 ?  15  LEU G CD1 1 
ATOM   6809 C CD2 . LEU D 4 8   ? 131.806 96.673  173.875 1.00 156.40 ?  15  LEU G CD2 1 
ATOM   6810 N N   . VAL D 4 9   ? 132.097 97.177  179.154 1.00 158.04 ?  16  VAL G N   1 
ATOM   6811 C CA  . VAL D 4 9   ? 131.161 96.824  180.218 1.00 158.32 ?  16  VAL G CA  1 
ATOM   6812 C C   . VAL D 4 9   ? 130.944 98.005  181.159 1.00 156.92 ?  16  VAL G C   1 
ATOM   6813 O O   . VAL D 4 9   ? 129.807 98.298  181.557 1.00 155.51 ?  16  VAL G O   1 
ATOM   6814 C CB  . VAL D 4 9   ? 131.658 95.577  180.970 1.00 157.40 ?  16  VAL G CB  1 
ATOM   6815 C CG1 . VAL D 4 9   ? 130.924 95.417  182.288 1.00 156.84 ?  16  VAL G CG1 1 
ATOM   6816 C CG2 . VAL D 4 9   ? 131.479 94.339  180.109 1.00 156.36 ?  16  VAL G CG2 1 
ATOM   6817 N N   . GLU D 4 10  ? 132.024 98.697  181.534 1.00 153.96 ?  17  GLU G N   1 
ATOM   6818 C CA  . GLU D 4 10  ? 131.884 99.873  182.392 1.00 154.08 ?  17  GLU G CA  1 
ATOM   6819 C C   . GLU D 4 10  ? 130.986 100.914 181.736 1.00 154.21 ?  17  GLU G C   1 
ATOM   6820 O O   . GLU D 4 10  ? 130.069 101.455 182.368 1.00 152.25 ?  17  GLU G O   1 
ATOM   6821 C CB  . GLU D 4 10  ? 133.254 100.489 182.697 1.00 153.83 ?  17  GLU G CB  1 
ATOM   6822 C CG  . GLU D 4 10  ? 134.380 99.595  183.266 1.00 155.56 ?  17  GLU G CG  1 
ATOM   6823 C CD  . GLU D 4 10  ? 133.942 98.356  184.045 1.00 157.82 ?  17  GLU G CD  1 
ATOM   6824 O OE1 . GLU D 4 10  ? 134.737 97.392  184.087 1.00 156.95 ?  17  GLU G OE1 1 
ATOM   6825 O OE2 . GLU D 4 10  ? 132.875 98.359  184.689 1.00 157.52 -1 17  GLU G OE2 1 
ATOM   6826 N N   . GLN D 4 11  ? 131.236 101.198 180.455 1.00 143.30 ?  18  GLN G N   1 
ATOM   6827 C CA  . GLN D 4 11  ? 130.439 102.186 179.737 1.00 140.80 ?  18  GLN G CA  1 
ATOM   6828 C C   . GLN D 4 11  ? 128.982 101.757 179.644 1.00 141.99 ?  18  GLN G C   1 
ATOM   6829 O O   . GLN D 4 11  ? 128.074 102.584 179.783 1.00 143.36 ?  18  GLN G O   1 
ATOM   6830 C CB  . GLN D 4 11  ? 131.023 102.409 178.342 1.00 139.03 ?  18  GLN G CB  1 
ATOM   6831 C CG  . GLN D 4 11  ? 130.486 103.629 177.613 1.00 139.27 ?  18  GLN G CG  1 
ATOM   6832 C CD  . GLN D 4 11  ? 130.307 104.825 178.522 1.00 138.42 ?  18  GLN G CD  1 
ATOM   6833 O OE1 . GLN D 4 11  ? 131.254 105.278 179.165 1.00 139.49 ?  18  GLN G OE1 1 
ATOM   6834 N NE2 . GLN D 4 11  ? 129.090 105.351 178.575 1.00 137.54 ?  18  GLN G NE2 1 
ATOM   6835 N N   . LEU D 4 12  ? 128.738 100.468 179.402 1.00 145.55 ?  19  LEU G N   1 
ATOM   6836 C CA  . LEU D 4 12  ? 127.369 99.985  179.276 1.00 143.49 ?  19  LEU G CA  1 
ATOM   6837 C C   . LEU D 4 12  ? 126.609 100.107 180.590 1.00 142.71 ?  19  LEU G C   1 
ATOM   6838 O O   . LEU D 4 12  ? 125.448 100.531 180.598 1.00 142.66 ?  19  LEU G O   1 
ATOM   6839 C CB  . LEU D 4 12  ? 127.367 98.540  178.784 1.00 144.95 ?  19  LEU G CB  1 
ATOM   6840 C CG  . LEU D 4 12  ? 127.004 98.357  177.310 1.00 144.87 ?  19  LEU G CG  1 
ATOM   6841 C CD1 . LEU D 4 12  ? 125.556 98.738  177.071 1.00 143.92 ?  19  LEU G CD1 1 
ATOM   6842 C CD2 . LEU D 4 12  ? 127.926 99.172  176.423 1.00 143.26 ?  19  LEU G CD2 1 
ATOM   6843 N N   . LYS D 4 13  ? 127.236 99.743  181.713 1.00 147.03 ?  20  LYS G N   1 
ATOM   6844 C CA  . LYS D 4 13  ? 126.536 99.911  182.985 1.00 147.75 ?  20  LYS G CA  1 
ATOM   6845 C C   . LYS D 4 13  ? 126.349 101.381 183.335 1.00 146.40 ?  20  LYS G C   1 
ATOM   6846 O O   . LYS D 4 13  ? 125.334 101.743 183.940 1.00 144.97 ?  20  LYS G O   1 
ATOM   6847 C CB  . LYS D 4 13  ? 127.249 99.187  184.129 1.00 147.72 ?  20  LYS G CB  1 
ATOM   6848 C CG  . LYS D 4 13  ? 127.739 97.790  183.815 1.00 149.33 ?  20  LYS G CG  1 
ATOM   6849 C CD  . LYS D 4 13  ? 128.536 97.237  184.984 1.00 149.63 ?  20  LYS G CD  1 
ATOM   6850 C CE  . LYS D 4 13  ? 129.871 97.934  185.131 1.00 149.22 ?  20  LYS G CE  1 
ATOM   6851 N NZ  . LYS D 4 13  ? 131.008 96.974  185.178 1.00 148.17 1  20  LYS G NZ  1 
ATOM   6852 N N   . MET D 4 14  ? 127.305 102.240 182.973 1.00 147.37 ?  21  MET G N   1 
ATOM   6853 C CA  . MET D 4 14  ? 127.116 103.671 183.191 1.00 146.37 ?  21  MET G CA  1 
ATOM   6854 C C   . MET D 4 14  ? 125.938 104.198 182.382 1.00 144.51 ?  21  MET G C   1 
ATOM   6855 O O   . MET D 4 14  ? 125.161 105.028 182.868 1.00 141.98 ?  21  MET G O   1 
ATOM   6856 C CB  . MET D 4 14  ? 128.393 104.433 182.838 1.00 144.59 ?  21  MET G CB  1 
ATOM   6857 C CG  . MET D 4 14  ? 129.384 104.549 183.982 1.00 144.65 ?  21  MET G CG  1 
ATOM   6858 S SD  . MET D 4 14  ? 128.697 105.403 185.413 1.00 154.05 ?  21  MET G SD  1 
ATOM   6859 C CE  . MET D 4 14  ? 128.654 104.072 186.611 1.00 144.50 ?  21  MET G CE  1 
ATOM   6860 N N   . GLU D 4 15  ? 125.791 103.727 181.143 1.00 135.36 ?  22  GLU G N   1 
ATOM   6861 C CA  . GLU D 4 15  ? 124.695 104.185 180.297 1.00 132.02 ?  22  GLU G CA  1 
ATOM   6862 C C   . GLU D 4 15  ? 123.357 103.609 180.737 1.00 134.41 ?  22  GLU G C   1 
ATOM   6863 O O   . GLU D 4 15  ? 122.317 104.246 180.540 1.00 134.81 ?  22  GLU G O   1 
ATOM   6864 C CB  . GLU D 4 15  ? 124.971 103.818 178.840 1.00 131.63 ?  22  GLU G CB  1 
ATOM   6865 C CG  . GLU D 4 15  ? 125.544 104.956 178.016 1.00 132.81 ?  22  GLU G CG  1 
ATOM   6866 C CD  . GLU D 4 15  ? 126.415 104.470 176.876 1.00 134.84 ?  22  GLU G CD  1 
ATOM   6867 O OE1 . GLU D 4 15  ? 125.917 103.693 176.036 1.00 135.20 ?  22  GLU G OE1 1 
ATOM   6868 O OE2 . GLU D 4 15  ? 127.597 104.867 176.821 1.00 131.88 -1 22  GLU G OE2 1 
ATOM   6869 N N   . ALA D 4 16  ? 123.355 102.408 181.316 1.00 143.06 ?  23  ALA G N   1 
ATOM   6870 C CA  . ALA D 4 16  ? 122.100 101.784 181.719 1.00 142.38 ?  23  ALA G CA  1 
ATOM   6871 C C   . ALA D 4 16  ? 121.536 102.383 183.000 1.00 143.74 ?  23  ALA G C   1 
ATOM   6872 O O   . ALA D 4 16  ? 120.317 102.366 183.199 1.00 144.44 ?  23  ALA G O   1 
ATOM   6873 C CB  . ALA D 4 16  ? 122.293 100.278 181.890 1.00 138.56 ?  23  ALA G CB  1 
ATOM   6874 N N   . ASN D 4 17  ? 122.390 102.910 183.874 1.00 145.30 ?  24  ASN G N   1 
ATOM   6875 C CA  . ASN D 4 17  ? 121.951 103.405 185.179 1.00 145.94 ?  24  ASN G CA  1 
ATOM   6876 C C   . ASN D 4 17  ? 121.656 104.905 185.126 1.00 144.78 ?  24  ASN G C   1 
ATOM   6877 O O   . ASN D 4 17  ? 122.242 105.715 185.842 1.00 146.48 ?  24  ASN G O   1 
ATOM   6878 C CB  . ASN D 4 17  ? 122.996 103.084 186.241 1.00 146.49 ?  24  ASN G CB  1 
ATOM   6879 C CG  . ASN D 4 17  ? 123.269 101.598 186.358 1.00 147.21 ?  24  ASN G CG  1 
ATOM   6880 O OD1 . ASN D 4 17  ? 122.384 100.773 186.134 1.00 144.64 ?  24  ASN G OD1 1 
ATOM   6881 N ND2 . ASN D 4 17  ? 124.501 101.250 186.713 1.00 147.16 ?  24  ASN G ND2 1 
ATOM   6882 N N   . ILE D 4 18  ? 120.717 105.269 184.252 1.00 135.60 ?  25  ILE G N   1 
ATOM   6883 C CA  . ILE D 4 18  ? 120.267 106.647 184.122 1.00 135.92 ?  25  ILE G CA  1 
ATOM   6884 C C   . ILE D 4 18  ? 118.749 106.681 184.233 1.00 137.13 ?  25  ILE G C   1 
ATOM   6885 O O   . ILE D 4 18  ? 118.061 105.679 184.027 1.00 134.15 ?  25  ILE G O   1 
ATOM   6886 C CB  . ILE D 4 18  ? 120.727 107.305 182.800 1.00 134.65 ?  25  ILE G CB  1 
ATOM   6887 C CG1 . ILE D 4 18  ? 119.732 107.017 181.675 1.00 134.37 ?  25  ILE G CG1 1 
ATOM   6888 C CG2 . ILE D 4 18  ? 122.129 106.855 182.427 1.00 135.84 ?  25  ILE G CG2 1 
ATOM   6889 C CD1 . ILE D 4 18  ? 120.178 107.521 180.325 1.00 132.25 ?  25  ILE G CD1 1 
ATOM   6890 N N   . ASP D 4 19  ? 118.234 107.859 184.574 1.00 145.91 ?  26  ASP G N   1 
ATOM   6891 C CA  . ASP D 4 19  ? 116.799 108.049 184.723 1.00 144.71 ?  26  ASP G CA  1 
ATOM   6892 C C   . ASP D 4 19  ? 116.158 108.255 183.358 1.00 143.70 ?  26  ASP G C   1 
ATOM   6893 O O   . ASP D 4 19  ? 116.605 109.095 182.572 1.00 146.23 ?  26  ASP G O   1 
ATOM   6894 C CB  . ASP D 4 19  ? 116.510 109.242 185.632 1.00 145.08 ?  26  ASP G CB  1 
ATOM   6895 C CG  . ASP D 4 19  ? 117.236 109.153 186.959 1.00 146.44 ?  26  ASP G CG  1 
ATOM   6896 O OD1 . ASP D 4 19  ? 117.703 108.050 187.310 1.00 145.41 ?  26  ASP G OD1 1 
ATOM   6897 O OD2 . ASP D 4 19  ? 117.341 110.187 187.651 1.00 145.19 -1 26  ASP G OD2 1 
ATOM   6898 N N   . ARG D 4 20  ? 115.107 107.492 183.083 1.00 125.91 ?  27  ARG G N   1 
ATOM   6899 C CA  . ARG D 4 20  ? 114.431 107.512 181.795 1.00 127.09 ?  27  ARG G CA  1 
ATOM   6900 C C   . ARG D 4 20  ? 113.068 108.171 181.946 1.00 126.21 ?  27  ARG G C   1 
ATOM   6901 O O   . ARG D 4 20  ? 112.290 107.803 182.832 1.00 126.47 ?  27  ARG G O   1 
ATOM   6902 C CB  . ARG D 4 20  ? 114.277 106.096 181.242 1.00 129.20 ?  27  ARG G CB  1 
ATOM   6903 C CG  . ARG D 4 20  ? 114.493 105.986 179.749 1.00 126.17 ?  27  ARG G CG  1 
ATOM   6904 C CD  . ARG D 4 20  ? 115.960 106.107 179.411 1.00 128.05 ?  27  ARG G CD  1 
ATOM   6905 N NE  . ARG D 4 20  ? 116.792 105.226 180.220 1.00 130.48 ?  27  ARG G NE  1 
ATOM   6906 C CZ  . ARG D 4 20  ? 117.066 103.966 179.915 1.00 129.17 ?  27  ARG G CZ  1 
ATOM   6907 N NH1 . ARG D 4 20  ? 116.583 103.401 178.821 1.00 131.45 1  27  ARG G NH1 1 
ATOM   6908 N NH2 . ARG D 4 20  ? 117.847 103.257 180.724 1.00 126.06 ?  27  ARG G NH2 1 
ATOM   6909 N N   . ILE D 4 21  ? 112.785 109.135 181.083 1.00 123.70 ?  28  ILE G N   1 
ATOM   6910 C CA  . ILE D 4 21  ? 111.524 109.865 181.088 1.00 126.40 ?  28  ILE G CA  1 
ATOM   6911 C C   . ILE D 4 21  ? 110.609 109.256 180.036 1.00 123.97 ?  28  ILE G C   1 
ATOM   6912 O O   . ILE D 4 21  ? 111.064 108.861 178.956 1.00 128.07 ?  28  ILE G O   1 
ATOM   6913 C CB  . ILE D 4 21  ? 111.760 111.368 180.836 1.00 128.33 ?  28  ILE G CB  1 
ATOM   6914 C CG1 . ILE D 4 21  ? 112.156 112.071 182.136 1.00 126.62 ?  28  ILE G CG1 1 
ATOM   6915 C CG2 . ILE D 4 21  ? 110.541 112.030 180.223 1.00 121.21 ?  28  ILE G CG2 1 
ATOM   6916 C CD1 . ILE D 4 21  ? 113.645 112.262 182.299 1.00 125.76 ?  28  ILE G CD1 1 
ATOM   6917 N N   . LYS D 4 22  ? 109.321 109.160 180.359 1.00 116.75 ?  29  LYS G N   1 
ATOM   6918 C CA  . LYS D 4 22  ? 108.353 108.592 179.432 1.00 121.08 ?  29  LYS G CA  1 
ATOM   6919 C C   . LYS D 4 22  ? 108.370 109.357 178.115 1.00 122.81 ?  29  LYS G C   1 
ATOM   6920 O O   . LYS D 4 22  ? 108.517 110.581 178.090 1.00 127.81 ?  29  LYS G O   1 
ATOM   6921 C CB  . LYS D 4 22  ? 106.955 108.633 180.046 1.00 122.91 ?  29  LYS G CB  1 
ATOM   6922 C CG  . LYS D 4 22  ? 105.988 107.613 179.480 1.00 121.42 ?  29  LYS G CG  1 
ATOM   6923 C CD  . LYS D 4 22  ? 106.401 106.205 179.860 1.00 124.18 ?  29  LYS G CD  1 
ATOM   6924 C CE  . LYS D 4 22  ? 105.916 105.856 181.256 1.00 120.39 ?  29  LYS G CE  1 
ATOM   6925 N NZ  . LYS D 4 22  ? 105.899 104.388 181.492 1.00 121.36 1  29  LYS G NZ  1 
ATOM   6926 N N   . VAL D 4 23  ? 108.233 108.622 177.010 1.00 119.49 ?  30  VAL G N   1 
ATOM   6927 C CA  . VAL D 4 23  ? 108.333 109.239 175.692 1.00 119.38 ?  30  VAL G CA  1 
ATOM   6928 C C   . VAL D 4 23  ? 107.178 110.200 175.442 1.00 121.34 ?  30  VAL G C   1 
ATOM   6929 O O   . VAL D 4 23  ? 107.352 111.228 174.777 1.00 125.57 ?  30  VAL G O   1 
ATOM   6930 C CB  . VAL D 4 23  ? 108.418 108.152 174.604 1.00 118.55 ?  30  VAL G CB  1 
ATOM   6931 C CG1 . VAL D 4 23  ? 107.201 107.260 174.648 1.00 124.84 ?  30  VAL G CG1 1 
ATOM   6932 C CG2 . VAL D 4 23  ? 108.557 108.776 173.235 1.00 115.10 ?  30  VAL G CG2 1 
ATOM   6933 N N   . SER D 4 24  ? 105.987 109.893 175.960 1.00 123.24 ?  31  SER G N   1 
ATOM   6934 C CA  . SER D 4 24  ? 104.821 110.728 175.684 1.00 125.80 ?  31  SER G CA  1 
ATOM   6935 C C   . SER D 4 24  ? 105.007 112.138 176.232 1.00 126.71 ?  31  SER G C   1 
ATOM   6936 O O   . SER D 4 24  ? 104.730 113.127 175.542 1.00 126.11 ?  31  SER G O   1 
ATOM   6937 C CB  . SER D 4 24  ? 103.567 110.081 176.270 1.00 125.99 ?  31  SER G CB  1 
ATOM   6938 O OG  . SER D 4 24  ? 102.648 111.061 176.716 1.00 124.88 ?  31  SER G OG  1 
ATOM   6939 N N   . LYS D 4 25  ? 105.498 112.256 177.467 1.00 122.99 ?  32  LYS G N   1 
ATOM   6940 C CA  . LYS D 4 25  ? 105.633 113.582 178.057 1.00 123.84 ?  32  LYS G CA  1 
ATOM   6941 C C   . LYS D 4 25  ? 106.795 114.354 177.446 1.00 123.27 ?  32  LYS G C   1 
ATOM   6942 O O   . LYS D 4 25  ? 106.742 115.584 177.366 1.00 127.90 ?  32  LYS G O   1 
ATOM   6943 C CB  . LYS D 4 25  ? 105.785 113.478 179.574 1.00 121.40 ?  32  LYS G CB  1 
ATOM   6944 C CG  . LYS D 4 25  ? 107.152 113.060 180.050 1.00 124.00 ?  32  LYS G CG  1 
ATOM   6945 C CD  . LYS D 4 25  ? 107.307 113.309 181.541 1.00 126.89 ?  32  LYS G CD  1 
ATOM   6946 C CE  . LYS D 4 25  ? 107.258 114.792 181.861 1.00 125.99 ?  32  LYS G CE  1 
ATOM   6947 N NZ  . LYS D 4 25  ? 108.025 115.600 180.876 1.00 123.17 1  32  LYS G NZ  1 
ATOM   6948 N N   . ALA D 4 26  ? 107.834 113.663 176.980 1.00 106.58 ?  33  ALA G N   1 
ATOM   6949 C CA  . ALA D 4 26  ? 108.924 114.362 176.308 1.00 106.02 ?  33  ALA G CA  1 
ATOM   6950 C C   . ALA D 4 26  ? 108.498 114.848 174.927 1.00 109.58 ?  33  ALA G C   1 
ATOM   6951 O O   . ALA D 4 26  ? 108.898 115.935 174.489 1.00 117.26 ?  33  ALA G O   1 
ATOM   6952 C CB  . ALA D 4 26  ? 110.142 113.452 176.219 1.00 109.46 ?  33  ALA G CB  1 
ATOM   6953 N N   . ALA D 4 27  ? 107.675 114.062 174.232 1.00 111.66 ?  34  ALA G N   1 
ATOM   6954 C CA  . ALA D 4 27  ? 107.068 114.542 172.997 1.00 109.88 ?  34  ALA G CA  1 
ATOM   6955 C C   . ALA D 4 27  ? 106.180 115.748 173.261 1.00 111.11 ?  34  ALA G C   1 
ATOM   6956 O O   . ALA D 4 27  ? 106.168 116.708 172.480 1.00 111.11 ?  34  ALA G O   1 
ATOM   6957 C CB  . ALA D 4 27  ? 106.264 113.422 172.343 1.00 105.39 ?  34  ALA G CB  1 
ATOM   6958 N N   . ALA D 4 28  ? 105.424 115.713 174.361 1.00 113.30 ?  35  ALA G N   1 
ATOM   6959 C CA  . ALA D 4 28  ? 104.622 116.867 174.747 1.00 110.62 ?  35  ALA G CA  1 
ATOM   6960 C C   . ALA D 4 28  ? 105.499 118.082 175.023 1.00 112.10 ?  35  ALA G C   1 
ATOM   6961 O O   . ALA D 4 28  ? 105.120 119.211 174.706 1.00 117.44 ?  35  ALA G O   1 
ATOM   6962 C CB  . ALA D 4 28  ? 103.771 116.528 175.969 1.00 108.01 ?  35  ALA G CB  1 
ATOM   6963 N N   . ASP D 4 29  ? 106.669 117.872 175.630 1.00 108.95 ?  36  ASP G N   1 
ATOM   6964 C CA  . ASP D 4 29  ? 107.590 118.978 175.882 1.00 107.17 ?  36  ASP G CA  1 
ATOM   6965 C C   . ASP D 4 29  ? 108.110 119.581 174.582 1.00 105.90 ?  36  ASP G C   1 
ATOM   6966 O O   . ASP D 4 29  ? 108.212 120.809 174.456 1.00 115.59 ?  36  ASP G O   1 
ATOM   6967 C CB  . ASP D 4 29  ? 108.755 118.504 176.746 1.00 110.54 ?  36  ASP G CB  1 
ATOM   6968 C CG  . ASP D 4 29  ? 108.416 118.487 178.219 1.00 115.83 ?  36  ASP G CG  1 
ATOM   6969 O OD1 . ASP D 4 29  ? 107.214 118.526 178.551 1.00 118.27 ?  36  ASP G OD1 1 
ATOM   6970 O OD2 . ASP D 4 29  ? 109.352 118.433 179.044 1.00 114.76 -1 36  ASP G OD2 1 
ATOM   6971 N N   . LEU D 4 30  ? 108.462 118.735 173.613 1.00 98.09  ?  37  LEU G N   1 
ATOM   6972 C CA  . LEU D 4 30  ? 108.882 119.250 172.312 1.00 100.27 ?  37  LEU G CA  1 
ATOM   6973 C C   . LEU D 4 30  ? 107.761 120.041 171.650 1.00 105.06 ?  37  LEU G C   1 
ATOM   6974 O O   . LEU D 4 30  ? 107.991 121.126 171.095 1.00 106.65 ?  37  LEU G O   1 
ATOM   6975 C CB  . LEU D 4 30  ? 109.330 118.102 171.410 1.00 101.54 ?  37  LEU G CB  1 
ATOM   6976 C CG  . LEU D 4 30  ? 110.832 117.934 171.194 1.00 103.89 ?  37  LEU G CG  1 
ATOM   6977 C CD1 . LEU D 4 30  ? 111.489 117.316 172.414 1.00 105.98 ?  37  LEU G CD1 1 
ATOM   6978 C CD2 . LEU D 4 30  ? 111.081 117.087 169.967 1.00 101.60 ?  37  LEU G CD2 1 
ATOM   6979 N N   . MET D 4 31  ? 106.536 119.514 171.710 1.00 109.86 ?  38  MET G N   1 
ATOM   6980 C CA  . MET D 4 31  ? 105.386 120.233 171.176 1.00 107.47 ?  38  MET G CA  1 
ATOM   6981 C C   . MET D 4 31  ? 105.210 121.578 171.864 1.00 108.28 ?  38  MET G C   1 
ATOM   6982 O O   . MET D 4 31  ? 104.919 122.586 171.211 1.00 111.03 ?  38  MET G O   1 
ATOM   6983 C CB  . MET D 4 31  ? 104.123 119.395 171.350 1.00 109.03 ?  38  MET G CB  1 
ATOM   6984 C CG  . MET D 4 31  ? 103.131 119.511 170.219 1.00 113.56 ?  38  MET G CG  1 
ATOM   6985 S SD  . MET D 4 31  ? 101.573 118.696 170.607 1.00 131.38 ?  38  MET G SD  1 
ATOM   6986 C CE  . MET D 4 31  ? 102.103 117.529 171.851 1.00 112.23 ?  38  MET G CE  1 
ATOM   6987 N N   . ALA D 4 32  ? 105.360 121.605 173.189 1.00 97.38  ?  39  ALA G N   1 
ATOM   6988 C CA  . ALA D 4 32  ? 105.187 122.840 173.939 1.00 97.29  ?  39  ALA G CA  1 
ATOM   6989 C C   . ALA D 4 32  ? 106.218 123.878 173.533 1.00 101.00 ?  39  ALA G C   1 
ATOM   6990 O O   . ALA D 4 32  ? 105.880 125.048 173.331 1.00 106.98 ?  39  ALA G O   1 
ATOM   6991 C CB  . ALA D 4 32  ? 105.273 122.559 175.438 1.00 95.07  ?  39  ALA G CB  1 
ATOM   6992 N N   . TYR D 4 33  ? 107.482 123.469 173.401 1.00 88.49  ?  40  TYR G N   1 
ATOM   6993 C CA  . TYR D 4 33  ? 108.511 124.413 172.976 1.00 84.05  ?  40  TYR G CA  1 
ATOM   6994 C C   . TYR D 4 33  ? 108.203 124.962 171.590 1.00 92.26  ?  40  TYR G C   1 
ATOM   6995 O O   . TYR D 4 33  ? 108.305 126.173 171.347 1.00 99.58  ?  40  TYR G O   1 
ATOM   6996 C CB  . TYR D 4 33  ? 109.885 123.746 172.994 1.00 85.24  ?  40  TYR G CB  1 
ATOM   6997 C CG  . TYR D 4 33  ? 111.017 124.690 172.660 1.00 89.46  ?  40  TYR G CG  1 
ATOM   6998 C CD1 . TYR D 4 33  ? 111.389 124.924 171.344 1.00 91.24  ?  40  TYR G CD1 1 
ATOM   6999 C CD2 . TYR D 4 33  ? 111.716 125.344 173.661 1.00 87.05  ?  40  TYR G CD2 1 
ATOM   7000 C CE1 . TYR D 4 33  ? 112.416 125.785 171.038 1.00 89.30  ?  40  TYR G CE1 1 
ATOM   7001 C CE2 . TYR D 4 33  ? 112.747 126.205 173.362 1.00 85.70  ?  40  TYR G CE2 1 
ATOM   7002 C CZ  . TYR D 4 33  ? 113.092 126.422 172.050 1.00 90.19  ?  40  TYR G CZ  1 
ATOM   7003 O OH  . TYR D 4 33  ? 114.119 127.281 171.747 1.00 90.82  ?  40  TYR G OH  1 
ATOM   7004 N N   . CYS D 4 34  ? 107.820 124.079 170.664 1.00 102.47 ?  41  CYS G N   1 
ATOM   7005 C CA  . CYS D 4 34  ? 107.544 124.527 169.304 1.00 100.06 ?  41  CYS G CA  1 
ATOM   7006 C C   . CYS D 4 34  ? 106.372 125.500 169.266 1.00 102.06 ?  41  CYS G C   1 
ATOM   7007 O O   . CYS D 4 34  ? 106.444 126.543 168.608 1.00 103.81 ?  41  CYS G O   1 
ATOM   7008 C CB  . CYS D 4 34  ? 107.275 123.324 168.404 1.00 102.97 ?  41  CYS G CB  1 
ATOM   7009 S SG  . CYS D 4 34  ? 108.743 122.689 167.580 1.00 105.65 ?  41  CYS G SG  1 
ATOM   7010 N N   . GLU D 4 35  ? 105.287 125.187 169.979 1.00 104.78 ?  42  GLU G N   1 
ATOM   7011 C CA  . GLU D 4 35  ? 104.119 126.061 169.950 1.00 102.40 ?  42  GLU G CA  1 
ATOM   7012 C C   . GLU D 4 35  ? 104.376 127.360 170.698 1.00 106.19 ?  42  GLU G C   1 
ATOM   7013 O O   . GLU D 4 35  ? 103.769 128.386 170.376 1.00 110.77 ?  42  GLU G O   1 
ATOM   7014 C CB  . GLU D 4 35  ? 102.889 125.295 170.474 1.00 100.07 ?  42  GLU G CB  1 
ATOM   7015 C CG  . GLU D 4 35  ? 102.817 124.863 171.963 1.00 106.19 ?  42  GLU G CG  1 
ATOM   7016 C CD  . GLU D 4 35  ? 102.805 125.967 173.020 1.00 112.67 ?  42  GLU G CD  1 
ATOM   7017 O OE1 . GLU D 4 35  ? 102.850 125.614 174.217 1.00 112.33 ?  42  GLU G OE1 1 
ATOM   7018 O OE2 . GLU D 4 35  ? 102.624 127.156 172.693 1.00 112.67 -1 42  GLU G OE2 1 
ATOM   7019 N N   . ALA D 4 36  ? 105.265 127.343 171.691 1.00 100.16 ?  43  ALA G N   1 
ATOM   7020 C CA  . ALA D 4 36  ? 105.574 128.569 172.413 1.00 97.59  ?  43  ALA G CA  1 
ATOM   7021 C C   . ALA D 4 36  ? 106.427 129.505 171.571 1.00 103.89 ?  43  ALA G C   1 
ATOM   7022 O O   . ALA D 4 36  ? 106.219 130.723 171.590 1.00 110.84 ?  43  ALA G O   1 
ATOM   7023 C CB  . ALA D 4 36  ? 106.277 128.243 173.728 1.00 91.44  ?  43  ALA G CB  1 
ATOM   7024 N N   . HIS D 4 37  ? 107.387 128.965 170.824 1.00 103.50 ?  44  HIS G N   1 
ATOM   7025 C CA  . HIS D 4 37  ? 108.307 129.807 170.075 1.00 99.14  ?  44  HIS G CA  1 
ATOM   7026 C C   . HIS D 4 37  ? 107.961 129.908 168.594 1.00 104.79 ?  44  HIS G C   1 
ATOM   7027 O O   . HIS D 4 37  ? 108.761 130.443 167.822 1.00 110.58 ?  44  HIS G O   1 
ATOM   7028 C CB  . HIS D 4 37  ? 109.739 129.305 170.248 1.00 98.76  ?  44  HIS G CB  1 
ATOM   7029 C CG  . HIS D 4 37  ? 110.266 129.470 171.637 1.00 101.97 ?  44  HIS G CG  1 
ATOM   7030 N ND1 . HIS D 4 37  ? 111.610 129.587 171.915 1.00 109.88 ?  44  HIS G ND1 1 
ATOM   7031 C CD2 . HIS D 4 37  ? 109.630 129.524 172.830 1.00 105.97 ?  44  HIS G CD2 1 
ATOM   7032 C CE1 . HIS D 4 37  ? 111.778 129.715 173.219 1.00 106.89 ?  44  HIS G CE1 1 
ATOM   7033 N NE2 . HIS D 4 37  ? 110.592 129.678 173.797 1.00 106.47 ?  44  HIS G NE2 1 
ATOM   7034 N N   . ALA D 4 38  ? 106.797 129.403 168.179 1.00 104.82 ?  45  ALA G N   1 
ATOM   7035 C CA  . ALA D 4 38  ? 106.403 129.527 166.779 1.00 105.89 ?  45  ALA G CA  1 
ATOM   7036 C C   . ALA D 4 38  ? 106.224 130.977 166.351 1.00 105.90 ?  45  ALA G C   1 
ATOM   7037 O O   . ALA D 4 38  ? 106.375 131.293 165.166 1.00 110.13 ?  45  ALA G O   1 
ATOM   7038 C CB  . ALA D 4 38  ? 105.112 128.748 166.528 1.00 106.44 ?  45  ALA G CB  1 
ATOM   7039 N N   . LYS D 4 39  ? 105.891 131.868 167.284 1.00 114.94 ?  46  LYS G N   1 
ATOM   7040 C CA  . LYS D 4 39  ? 105.595 133.245 166.904 1.00 117.70 ?  46  LYS G CA  1 
ATOM   7041 C C   . LYS D 4 39  ? 106.835 133.990 166.430 1.00 115.11 ?  46  LYS G C   1 
ATOM   7042 O O   . LYS D 4 39  ? 106.731 134.890 165.590 1.00 113.68 ?  46  LYS G O   1 
ATOM   7043 C CB  . LYS D 4 39  ? 104.948 133.985 168.072 1.00 116.81 ?  46  LYS G CB  1 
ATOM   7044 C CG  . LYS D 4 39  ? 103.646 134.673 167.710 1.00 118.08 ?  46  LYS G CG  1 
ATOM   7045 C CD  . LYS D 4 39  ? 102.743 133.750 166.911 1.00 120.24 ?  46  LYS G CD  1 
ATOM   7046 C CE  . LYS D 4 39  ? 101.368 134.361 166.713 1.00 117.69 ?  46  LYS G CE  1 
ATOM   7047 N NZ  . LYS D 4 39  ? 100.708 133.861 165.476 1.00 115.75 1  46  LYS G NZ  1 
ATOM   7048 N N   . GLU D 4 40  ? 108.008 133.636 166.945 1.00 116.48 ?  47  GLU G N   1 
ATOM   7049 C CA  . GLU D 4 40  ? 109.258 134.307 166.609 1.00 115.70 ?  47  GLU G CA  1 
ATOM   7050 C C   . GLU D 4 40  ? 110.122 133.460 165.680 1.00 119.00 ?  47  GLU G C   1 
ATOM   7051 O O   . GLU D 4 40  ? 111.347 133.432 165.798 1.00 121.49 ?  47  GLU G O   1 
ATOM   7052 C CB  . GLU D 4 40  ? 110.028 134.670 167.875 1.00 114.75 ?  47  GLU G CB  1 
ATOM   7053 C CG  . GLU D 4 40  ? 109.987 133.605 168.949 1.00 119.73 ?  47  GLU G CG  1 
ATOM   7054 C CD  . GLU D 4 40  ? 109.106 133.998 170.114 1.00 123.30 ?  47  GLU G CD  1 
ATOM   7055 O OE1 . GLU D 4 40  ? 108.012 134.547 169.868 1.00 120.49 ?  47  GLU G OE1 1 
ATOM   7056 O OE2 . GLU D 4 40  ? 109.503 133.762 171.273 1.00 122.75 -1 47  GLU G OE2 1 
ATOM   7057 N N   . ASP D 4 41  ? 109.487 132.762 164.738 1.00 101.94 ?  48  ASP G N   1 
ATOM   7058 C CA  . ASP D 4 41  ? 110.177 131.932 163.752 1.00 99.21  ?  48  ASP G CA  1 
ATOM   7059 C C   . ASP D 4 41  ? 109.855 132.474 162.366 1.00 101.00 ?  48  ASP G C   1 
ATOM   7060 O O   . ASP D 4 41  ? 108.854 132.077 161.751 1.00 102.46 ?  48  ASP G O   1 
ATOM   7061 C CB  . ASP D 4 41  ? 109.764 130.469 163.880 1.00 102.80 ?  48  ASP G CB  1 
ATOM   7062 C CG  . ASP D 4 41  ? 110.752 129.524 163.229 1.00 103.16 ?  48  ASP G CG  1 
ATOM   7063 O OD1 . ASP D 4 41  ? 111.708 130.009 162.590 1.00 100.77 ?  48  ASP G OD1 1 
ATOM   7064 O OD2 . ASP D 4 41  ? 110.571 128.296 163.355 1.00 102.34 -1 48  ASP G OD2 1 
ATOM   7065 N N   . PRO D 4 42  ? 110.669 133.390 161.840 1.00 96.95  ?  49  PRO G N   1 
ATOM   7066 C CA  . PRO D 4 42  ? 110.368 133.970 160.522 1.00 101.03 ?  49  PRO G CA  1 
ATOM   7067 C C   . PRO D 4 42  ? 110.390 132.970 159.381 1.00 104.05 ?  49  PRO G C   1 
ATOM   7068 O O   . PRO D 4 42  ? 109.773 133.232 158.343 1.00 111.88 ?  49  PRO G O   1 
ATOM   7069 C CB  . PRO D 4 42  ? 111.455 135.040 160.348 1.00 98.34  ?  49  PRO G CB  1 
ATOM   7070 C CG  . PRO D 4 42  ? 112.501 134.707 161.340 1.00 95.72  ?  49  PRO G CG  1 
ATOM   7071 C CD  . PRO D 4 42  ? 111.838 134.016 162.474 1.00 95.42  ?  49  PRO G CD  1 
ATOM   7072 N N   . LEU D 4 43  ? 111.091 131.846 159.522 1.00 102.19 ?  50  LEU G N   1 
ATOM   7073 C CA  . LEU D 4 43  ? 111.074 130.841 158.464 1.00 95.16  ?  50  LEU G CA  1 
ATOM   7074 C C   . LEU D 4 43  ? 109.724 130.145 158.393 1.00 97.63  ?  50  LEU G C   1 
ATOM   7075 O O   . LEU D 4 43  ? 109.232 129.838 157.302 1.00 99.75  ?  50  LEU G O   1 
ATOM   7076 C CB  . LEU D 4 43  ? 112.185 129.822 158.689 1.00 96.15  ?  50  LEU G CB  1 
ATOM   7077 C CG  . LEU D 4 43  ? 113.607 130.297 158.422 1.00 97.67  ?  50  LEU G CG  1 
ATOM   7078 C CD1 . LEU D 4 43  ? 114.561 129.154 158.653 1.00 101.96 ?  50  LEU G CD1 1 
ATOM   7079 C CD2 . LEU D 4 43  ? 113.737 130.832 157.014 1.00 93.64  ?  50  LEU G CD2 1 
ATOM   7080 N N   . LEU D 4 44  ? 109.117 129.879 159.548 1.00 100.30 ?  51  LEU G N   1 
ATOM   7081 C CA  . LEU D 4 44  ? 107.807 129.241 159.576 1.00 98.76  ?  51  LEU G CA  1 
ATOM   7082 C C   . LEU D 4 44  ? 106.744 130.165 159.001 1.00 104.42 ?  51  LEU G C   1 
ATOM   7083 O O   . LEU D 4 44  ? 106.093 129.841 158.002 1.00 108.92 ?  51  LEU G O   1 
ATOM   7084 C CB  . LEU D 4 44  ? 107.463 128.841 161.010 1.00 101.72 ?  51  LEU G CB  1 
ATOM   7085 C CG  . LEU D 4 44  ? 106.384 127.781 161.199 1.00 102.27 ?  51  LEU G CG  1 
ATOM   7086 C CD1 . LEU D 4 44  ? 106.918 126.433 160.786 1.00 108.30 ?  51  LEU G CD1 1 
ATOM   7087 C CD2 . LEU D 4 44  ? 105.926 127.756 162.642 1.00 97.87  ?  51  LEU G CD2 1 
ATOM   7088 N N   . THR D 4 45  ? 106.560 131.329 159.619 1.00 123.59 ?  52  THR G N   1 
ATOM   7089 C CA  . THR D 4 45  ? 105.617 132.321 159.132 1.00 125.71 ?  52  THR G CA  1 
ATOM   7090 C C   . THR D 4 45  ? 106.374 133.353 158.313 1.00 125.70 ?  52  THR G C   1 
ATOM   7091 O O   . THR D 4 45  ? 107.189 134.096 158.880 1.00 124.61 ?  52  THR G O   1 
ATOM   7092 C CB  . THR D 4 45  ? 104.894 132.992 160.296 1.00 127.07 ?  52  THR G CB  1 
ATOM   7093 O OG1 . THR D 4 45  ? 105.742 133.992 160.873 1.00 126.08 ?  52  THR G OG1 1 
ATOM   7094 C CG2 . THR D 4 45  ? 104.538 131.967 161.359 1.00 122.47 ?  52  THR G CG2 1 
ATOM   7095 N N   . PRO D 4 46  ? 106.149 133.442 157.003 1.00 133.50 ?  53  PRO G N   1 
ATOM   7096 C CA  . PRO D 4 46  ? 106.926 134.378 156.173 1.00 131.09 ?  53  PRO G CA  1 
ATOM   7097 C C   . PRO D 4 46  ? 106.770 135.812 156.655 1.00 133.67 ?  53  PRO G C   1 
ATOM   7098 O O   . PRO D 4 46  ? 105.674 136.376 156.645 1.00 132.80 ?  53  PRO G O   1 
ATOM   7099 C CB  . PRO D 4 46  ? 106.335 134.181 154.772 1.00 130.20 ?  53  PRO G CB  1 
ATOM   7100 C CG  . PRO D 4 46  ? 105.697 132.832 154.810 1.00 132.30 ?  53  PRO G CG  1 
ATOM   7101 C CD  . PRO D 4 46  ? 105.192 132.657 156.208 1.00 130.05 ?  53  PRO G CD  1 
ATOM   7102 N N   . VAL D 4 47  ? 107.883 136.395 157.087 1.00 132.84 ?  54  VAL G N   1 
ATOM   7103 C CA  . VAL D 4 47  ? 107.902 137.753 157.623 1.00 133.40 ?  54  VAL G CA  1 
ATOM   7104 C C   . VAL D 4 47  ? 107.670 138.729 156.474 1.00 135.05 ?  54  VAL G C   1 
ATOM   7105 O O   . VAL D 4 47  ? 108.064 138.444 155.332 1.00 131.32 ?  54  VAL G O   1 
ATOM   7106 C CB  . VAL D 4 47  ? 109.221 138.029 158.370 1.00 128.00 ?  54  VAL G CB  1 
ATOM   7107 C CG1 . VAL D 4 47  ? 110.191 138.835 157.516 1.00 128.19 ?  54  VAL G CG1 1 
ATOM   7108 C CG2 . VAL D 4 47  ? 108.957 138.715 159.702 1.00 124.64 ?  54  VAL G CG2 1 
ATOM   7109 N N   . PRO D 4 48  ? 107.007 139.860 156.707 1.00 139.52 ?  55  PRO G N   1 
ATOM   7110 C CA  . PRO D 4 48  ? 106.822 140.837 155.630 1.00 136.60 ?  55  PRO G CA  1 
ATOM   7111 C C   . PRO D 4 48  ? 108.139 141.468 155.212 1.00 137.62 ?  55  PRO G C   1 
ATOM   7112 O O   . PRO D 4 48  ? 109.091 141.558 155.991 1.00 137.67 ?  55  PRO G O   1 
ATOM   7113 C CB  . PRO D 4 48  ? 105.877 141.877 156.244 1.00 133.40 ?  55  PRO G CB  1 
ATOM   7114 C CG  . PRO D 4 48  ? 105.969 141.674 157.711 1.00 133.78 ?  55  PRO G CG  1 
ATOM   7115 C CD  . PRO D 4 48  ? 106.258 140.224 157.919 1.00 133.75 ?  55  PRO G CD  1 
ATOM   7116 N N   . ALA D 4 49  ? 108.179 141.921 153.959 1.00 133.76 ?  56  ALA G N   1 
ATOM   7117 C CA  . ALA D 4 49  ? 109.399 142.475 153.386 1.00 134.37 ?  56  ALA G CA  1 
ATOM   7118 C C   . ALA D 4 49  ? 109.800 143.805 154.006 1.00 134.18 ?  56  ALA G C   1 
ATOM   7119 O O   . ALA D 4 49  ? 110.903 144.286 153.726 1.00 129.82 ?  56  ALA G O   1 
ATOM   7120 C CB  . ALA D 4 49  ? 109.238 142.641 151.875 1.00 129.44 ?  56  ALA G CB  1 
ATOM   7121 N N   . SER D 4 50  ? 108.938 144.415 154.822 1.00 137.15 ?  57  SER G N   1 
ATOM   7122 C CA  . SER D 4 50  ? 109.278 145.699 155.426 1.00 136.77 ?  57  SER G CA  1 
ATOM   7123 C C   . SER D 4 50  ? 110.483 145.578 156.351 1.00 135.05 ?  57  SER G C   1 
ATOM   7124 O O   . SER D 4 50  ? 111.383 146.426 156.322 1.00 133.06 ?  57  SER G O   1 
ATOM   7125 C CB  . SER D 4 50  ? 108.076 146.256 156.186 1.00 135.17 ?  57  SER G CB  1 
ATOM   7126 O OG  . SER D 4 50  ? 107.933 145.620 157.442 1.00 135.78 ?  57  SER G OG  1 
ATOM   7127 N N   . GLU D 4 51  ? 110.525 144.530 157.176 1.00 133.00 ?  58  GLU G N   1 
ATOM   7128 C CA  . GLU D 4 51  ? 111.627 144.333 158.111 1.00 135.46 ?  58  GLU G CA  1 
ATOM   7129 C C   . GLU D 4 51  ? 112.440 143.082 157.793 1.00 135.10 ?  58  GLU G C   1 
ATOM   7130 O O   . GLU D 4 51  ? 113.218 142.620 158.633 1.00 134.06 ?  58  GLU G O   1 
ATOM   7131 C CB  . GLU D 4 51  ? 111.114 144.291 159.553 1.00 136.12 ?  58  GLU G CB  1 
ATOM   7132 C CG  . GLU D 4 51  ? 110.425 143.003 159.964 1.00 136.18 ?  58  GLU G CG  1 
ATOM   7133 C CD  . GLU D 4 51  ? 108.983 142.943 159.517 1.00 136.70 ?  58  GLU G CD  1 
ATOM   7134 O OE1 . GLU D 4 51  ? 108.481 143.949 158.974 1.00 135.50 ?  58  GLU G OE1 1 
ATOM   7135 O OE2 . GLU D 4 51  ? 108.343 141.894 159.728 1.00 137.50 -1 58  GLU G OE2 1 
ATOM   7136 N N   . ASN D 4 52  ? 112.286 142.533 156.596 1.00 121.69 ?  59  ASN G N   1 
ATOM   7137 C CA  . ASN D 4 52  ? 113.128 141.429 156.161 1.00 120.48 ?  59  ASN G CA  1 
ATOM   7138 C C   . ASN D 4 52  ? 114.474 141.973 155.701 1.00 118.88 ?  59  ASN G C   1 
ATOM   7139 O O   . ASN D 4 52  ? 114.522 142.725 154.722 1.00 118.84 ?  59  ASN G O   1 
ATOM   7140 C CB  . ASN D 4 52  ? 112.452 140.666 155.031 1.00 121.21 ?  59  ASN G CB  1 
ATOM   7141 C CG  . ASN D 4 52  ? 113.225 139.440 154.608 1.00 121.26 ?  59  ASN G CG  1 
ATOM   7142 O OD1 . ASN D 4 52  ? 114.166 139.023 155.278 1.00 122.86 ?  59  ASN G OD1 1 
ATOM   7143 N ND2 . ASN D 4 52  ? 112.831 138.852 153.487 1.00 119.38 ?  59  ASN G ND2 1 
ATOM   7144 N N   . PRO D 4 53  ? 115.579 141.630 156.367 1.00 104.09 ?  60  PRO G N   1 
ATOM   7145 C CA  . PRO D 4 53  ? 116.884 142.170 155.953 1.00 100.53 ?  60  PRO G CA  1 
ATOM   7146 C C   . PRO D 4 53  ? 117.332 141.706 154.582 1.00 101.91 ?  60  PRO G C   1 
ATOM   7147 O O   . PRO D 4 53  ? 118.188 142.358 153.974 1.00 103.29 ?  60  PRO G O   1 
ATOM   7148 C CB  . PRO D 4 53  ? 117.840 141.677 157.045 1.00 94.32  ?  60  PRO G CB  1 
ATOM   7149 C CG  . PRO D 4 53  ? 117.126 140.597 157.754 1.00 99.15  ?  60  PRO G CG  1 
ATOM   7150 C CD  . PRO D 4 53  ? 115.665 140.814 157.587 1.00 100.83 ?  60  PRO G CD  1 
ATOM   7151 N N   . PHE D 4 54  ? 116.793 140.600 154.077 1.00 97.38  ?  61  PHE G N   1 
ATOM   7152 C CA  . PHE D 4 54  ? 117.128 140.085 152.752 1.00 97.42  ?  61  PHE G CA  1 
ATOM   7153 C C   . PHE D 4 54  ? 116.017 140.359 151.751 1.00 101.14 ?  61  PHE G C   1 
ATOM   7154 O O   . PHE D 4 54  ? 115.725 139.526 150.891 1.00 105.93 ?  61  PHE G O   1 
ATOM   7155 C CB  . PHE D 4 54  ? 117.428 138.591 152.824 1.00 96.98  ?  61  PHE G CB  1 
ATOM   7156 C CG  . PHE D 4 54  ? 118.499 138.234 153.812 1.00 92.24  ?  61  PHE G CG  1 
ATOM   7157 C CD1 . PHE D 4 54  ? 119.831 138.276 153.453 1.00 85.62  ?  61  PHE G CD1 1 
ATOM   7158 C CD2 . PHE D 4 54  ? 118.172 137.854 155.100 1.00 92.89  ?  61  PHE G CD2 1 
ATOM   7159 C CE1 . PHE D 4 54  ? 120.812 137.949 154.357 1.00 88.85  ?  61  PHE G CE1 1 
ATOM   7160 C CE2 . PHE D 4 54  ? 119.152 137.529 156.008 1.00 88.00  ?  61  PHE G CE2 1 
ATOM   7161 C CZ  . PHE D 4 54  ? 120.473 137.576 155.636 1.00 91.78  ?  61  PHE G CZ  1 
ATOM   7162 N N   . ARG D 4 55  ? 115.379 141.529 151.851 1.00 125.59 ?  62  ARG G N   1 
ATOM   7163 C CA  . ARG D 4 55  ? 114.223 141.827 151.011 1.00 126.86 ?  62  ARG G CA  1 
ATOM   7164 C C   . ARG D 4 55  ? 114.578 141.822 149.530 1.00 129.74 ?  62  ARG G C   1 
ATOM   7165 O O   . ARG D 4 55  ? 113.725 141.509 148.692 1.00 129.67 ?  62  ARG G O   1 
ATOM   7166 C CB  . ARG D 4 55  ? 113.622 143.175 151.408 1.00 125.39 ?  62  ARG G CB  1 
ATOM   7167 C CG  . ARG D 4 55  ? 114.546 144.359 151.179 1.00 126.22 ?  62  ARG G CG  1 
ATOM   7168 C CD  . ARG D 4 55  ? 114.244 145.502 152.133 1.00 128.04 ?  62  ARG G CD  1 
ATOM   7169 N NE  . ARG D 4 55  ? 114.452 145.130 153.526 1.00 130.42 ?  62  ARG G NE  1 
ATOM   7170 C CZ  . ARG D 4 55  ? 114.589 145.999 154.518 1.00 130.37 ?  62  ARG G CZ  1 
ATOM   7171 N NH1 . ARG D 4 55  ? 114.550 147.303 154.304 1.00 124.85 1  62  ARG G NH1 1 
ATOM   7172 N NH2 . ARG D 4 55  ? 114.772 145.548 155.756 1.00 129.26 ?  62  ARG G NH2 1 
ATOM   7173 N N   . GLU D 4 56  ? 115.816 142.157 149.187 1.00 132.09 ?  63  GLU G N   1 
ATOM   7174 C CA  . GLU D 4 56  ? 116.249 142.133 147.795 1.00 135.73 ?  63  GLU G CA  1 
ATOM   7175 C C   . GLU D 4 56  ? 116.581 140.708 147.358 1.00 137.86 ?  63  GLU G C   1 
ATOM   7176 O O   . GLU D 4 56  ? 117.076 139.905 148.148 1.00 134.75 ?  63  GLU G O   1 
ATOM   7177 C CB  . GLU D 4 56  ? 117.459 143.046 147.591 1.00 131.38 ?  63  GLU G CB  1 
ATOM   7178 C CG  . GLU D 4 56  ? 117.868 143.221 146.138 1.00 130.15 ?  63  GLU G CG  1 
ATOM   7179 C CD  . GLU D 4 56  ? 116.697 143.567 145.242 1.00 134.47 ?  63  GLU G CD  1 
ATOM   7180 O OE1 . GLU D 4 56  ? 116.270 144.741 145.248 1.00 136.08 ?  63  GLU G OE1 1 
ATOM   7181 O OE2 . GLU D 4 56  ? 116.204 142.667 144.530 1.00 135.95 -1 63  GLU G OE2 1 
ATOM   7182 O OXT . GLU D 4 56  ? 116.364 140.321 146.210 1.00 133.04 -1 63  GLU G OXT 1 
ATOM   7183 N N   . ASP E 5 1   ? 155.270 147.771 166.362 1.00 114.25 ?  1   ASP S N   1 
ATOM   7184 C CA  . ASP E 5 1   ? 153.832 148.004 166.371 1.00 113.58 ?  1   ASP S CA  1 
ATOM   7185 C C   . ASP E 5 1   ? 153.430 148.916 165.222 1.00 117.12 ?  1   ASP S C   1 
ATOM   7186 O O   . ASP E 5 1   ? 154.236 149.204 164.340 1.00 117.34 ?  1   ASP S O   1 
ATOM   7187 C CB  . ASP E 5 1   ? 153.396 148.610 167.703 1.00 114.27 ?  1   ASP S CB  1 
ATOM   7188 C CG  . ASP E 5 1   ? 154.380 149.635 168.221 1.00 120.10 ?  1   ASP S CG  1 
ATOM   7189 O OD1 . ASP E 5 1   ? 155.393 149.883 167.534 1.00 117.34 ?  1   ASP S OD1 1 
ATOM   7190 O OD2 . ASP E 5 1   ? 154.142 150.194 169.311 1.00 120.05 -1 1   ASP S OD2 1 
ATOM   7191 N N   . VAL E 5 2   ? 152.178 149.371 165.242 1.00 103.33 ?  2   VAL S N   1 
ATOM   7192 C CA  . VAL E 5 2   ? 151.672 150.245 164.190 1.00 95.77  ?  2   VAL S CA  1 
ATOM   7193 C C   . VAL E 5 2   ? 152.313 151.617 164.340 1.00 93.03  ?  2   VAL S C   1 
ATOM   7194 O O   . VAL E 5 2   ? 152.214 152.252 165.395 1.00 92.75  ?  2   VAL S O   1 
ATOM   7195 C CB  . VAL E 5 2   ? 150.144 150.336 164.243 1.00 93.39  ?  2   VAL S CB  1 
ATOM   7196 C CG1 . VAL E 5 2   ? 149.635 151.243 163.148 1.00 95.20  ?  2   VAL S CG1 1 
ATOM   7197 C CG2 . VAL E 5 2   ? 149.531 148.957 164.116 1.00 90.21  ?  2   VAL S CG2 1 
ATOM   7198 N N   . GLN E 5 3   ? 152.974 152.080 163.283 1.00 91.50  ?  3   GLN S N   1 
ATOM   7199 C CA  . GLN E 5 3   ? 153.677 153.352 163.301 1.00 90.68  ?  3   GLN S CA  1 
ATOM   7200 C C   . GLN E 5 3   ? 153.414 154.102 162.005 1.00 99.22  ?  3   GLN S C   1 
ATOM   7201 O O   . GLN E 5 3   ? 153.244 153.500 160.943 1.00 101.08 ?  3   GLN S O   1 
ATOM   7202 C CB  . GLN E 5 3   ? 155.185 153.158 163.496 1.00 89.49  ?  3   GLN S CB  1 
ATOM   7203 C CG  . GLN E 5 3   ? 155.872 154.225 164.340 1.00 98.50  ?  3   GLN S CG  1 
ATOM   7204 C CD  . GLN E 5 3   ? 155.117 154.587 165.608 1.00 105.48 ?  3   GLN S CD  1 
ATOM   7205 O OE1 . GLN E 5 3   ? 154.454 153.750 166.220 1.00 107.68 ?  3   GLN S OE1 1 
ATOM   7206 N NE2 . GLN E 5 3   ? 155.217 155.849 166.008 1.00 100.17 ?  3   GLN S NE2 1 
ATOM   7207 N N   . LEU E 5 4   ? 153.382 155.429 162.107 1.00 98.66  ?  4   LEU S N   1 
ATOM   7208 C CA  . LEU E 5 4   ? 153.207 156.312 160.956 1.00 90.17  ?  4   LEU S CA  1 
ATOM   7209 C C   . LEU E 5 4   ? 154.059 157.547 161.200 1.00 91.76  ?  4   LEU S C   1 
ATOM   7210 O O   . LEU E 5 4   ? 153.697 158.396 162.019 1.00 99.68  ?  4   LEU S O   1 
ATOM   7211 C CB  . LEU E 5 4   ? 151.740 156.690 160.759 1.00 78.97  ?  4   LEU S CB  1 
ATOM   7212 C CG  . LEU E 5 4   ? 150.850 155.652 160.078 1.00 80.84  ?  4   LEU S CG  1 
ATOM   7213 C CD1 . LEU E 5 4   ? 149.394 156.040 160.191 1.00 81.33  ?  4   LEU S CD1 1 
ATOM   7214 C CD2 . LEU E 5 4   ? 151.239 155.496 158.630 1.00 86.07  ?  4   LEU S CD2 1 
ATOM   7215 N N   . VAL E 5 5   ? 155.185 157.647 160.503 1.00 93.09  ?  5   VAL S N   1 
ATOM   7216 C CA  . VAL E 5 5   ? 156.143 158.728 160.706 1.00 95.44  ?  5   VAL S CA  1 
ATOM   7217 C C   . VAL E 5 5   ? 156.017 159.715 159.557 1.00 101.49 ?  5   VAL S C   1 
ATOM   7218 O O   . VAL E 5 5   ? 155.982 159.317 158.386 1.00 103.14 ?  5   VAL S O   1 
ATOM   7219 C CB  . VAL E 5 5   ? 157.577 158.187 160.817 1.00 97.80  ?  5   VAL S CB  1 
ATOM   7220 C CG1 . VAL E 5 5   ? 158.566 159.331 160.911 1.00 95.70  ?  5   VAL S CG1 1 
ATOM   7221 C CG2 . VAL E 5 5   ? 157.700 157.276 162.021 1.00 98.58  ?  5   VAL S CG2 1 
ATOM   7222 N N   . GLU E 5 6   ? 155.951 161.000 159.889 1.00 109.09 ?  6   GLU S N   1 
ATOM   7223 C CA  . GLU E 5 6   ? 155.740 162.054 158.910 1.00 105.51 ?  6   GLU S CA  1 
ATOM   7224 C C   . GLU E 5 6   ? 157.045 162.796 158.666 1.00 110.23 ?  6   GLU S C   1 
ATOM   7225 O O   . GLU E 5 6   ? 157.794 163.080 159.604 1.00 112.14 ?  6   GLU S O   1 
ATOM   7226 C CB  . GLU E 5 6   ? 154.678 163.038 159.393 1.00 106.10 ?  6   GLU S CB  1 
ATOM   7227 C CG  . GLU E 5 6   ? 153.302 162.717 158.886 1.00 108.54 ?  6   GLU S CG  1 
ATOM   7228 C CD  . GLU E 5 6   ? 152.607 161.733 159.793 1.00 112.72 ?  6   GLU S CD  1 
ATOM   7229 O OE1 . GLU E 5 6   ? 152.261 160.641 159.324 1.00 116.85 ?  6   GLU S OE1 1 
ATOM   7230 O OE2 . GLU E 5 6   ? 152.395 162.053 160.978 1.00 104.28 -1 6   GLU S OE2 1 
ATOM   7231 N N   . SER E 5 7   ? 157.311 163.111 157.402 1.00 110.07 ?  7   SER S N   1 
ATOM   7232 C CA  . SER E 5 7   ? 158.512 163.847 157.044 1.00 105.37 ?  7   SER S CA  1 
ATOM   7233 C C   . SER E 5 7   ? 158.215 164.725 155.840 1.00 108.18 ?  7   SER S C   1 
ATOM   7234 O O   . SER E 5 7   ? 157.333 164.420 155.034 1.00 106.75 ?  7   SER S O   1 
ATOM   7235 C CB  . SER E 5 7   ? 159.680 162.903 156.743 1.00 104.40 ?  7   SER S CB  1 
ATOM   7236 O OG  . SER E 5 7   ? 159.458 162.187 155.543 1.00 107.89 ?  7   SER S OG  1 
ATOM   7237 N N   . GLY E 5 8   ? 158.963 165.819 155.728 1.00 109.30 ?  8   GLY S N   1 
ATOM   7238 C CA  . GLY E 5 8   ? 158.795 166.731 154.615 1.00 108.05 ?  8   GLY S CA  1 
ATOM   7239 C C   . GLY E 5 8   ? 158.251 168.085 155.015 1.00 109.40 ?  8   GLY S C   1 
ATOM   7240 O O   . GLY E 5 8   ? 157.658 168.788 154.194 1.00 110.37 ?  8   GLY S O   1 
ATOM   7241 N N   . GLY E 5 9   ? 158.436 168.463 156.279 1.00 117.57 ?  9   GLY S N   1 
ATOM   7242 C CA  . GLY E 5 9   ? 158.016 169.762 156.751 1.00 115.84 ?  9   GLY S CA  1 
ATOM   7243 C C   . GLY E 5 9   ? 159.098 170.810 156.578 1.00 119.37 ?  9   GLY S C   1 
ATOM   7244 O O   . GLY E 5 9   ? 160.176 170.557 156.042 1.00 118.56 ?  9   GLY S O   1 
ATOM   7245 N N   . GLY E 5 10  ? 158.794 172.010 157.045 1.00 120.79 ?  10  GLY S N   1 
ATOM   7246 C CA  . GLY E 5 10  ? 159.727 173.110 157.009 1.00 116.86 ?  10  GLY S CA  1 
ATOM   7247 C C   . GLY E 5 10  ? 159.037 174.383 156.578 1.00 118.43 ?  10  GLY S C   1 
ATOM   7248 O O   . GLY E 5 10  ? 157.813 174.448 156.478 1.00 120.27 ?  10  GLY S O   1 
ATOM   7249 N N   . LEU E 5 11  ? 159.843 175.407 156.320 1.00 118.84 ?  11  LEU S N   1 
ATOM   7250 C CA  . LEU E 5 11  ? 159.354 176.711 155.898 1.00 116.23 ?  11  LEU S CA  1 
ATOM   7251 C C   . LEU E 5 11  ? 159.390 176.790 154.378 1.00 116.83 ?  11  LEU S C   1 
ATOM   7252 O O   . LEU E 5 11  ? 160.417 176.494 153.761 1.00 118.68 ?  11  LEU S O   1 
ATOM   7253 C CB  . LEU E 5 11  ? 160.190 177.829 156.524 1.00 115.22 ?  11  LEU S CB  1 
ATOM   7254 C CG  . LEU E 5 11  ? 160.020 179.271 156.040 1.00 122.82 ?  11  LEU S CG  1 
ATOM   7255 C CD1 . LEU E 5 11  ? 160.190 180.224 157.208 1.00 119.36 ?  11  LEU S CD1 1 
ATOM   7256 C CD2 . LEU E 5 11  ? 161.022 179.612 154.947 1.00 121.26 ?  11  LEU S CD2 1 
ATOM   7257 N N   . VAL E 5 12  ? 158.269 177.184 153.781 1.00 117.42 ?  12  VAL S N   1 
ATOM   7258 C CA  . VAL E 5 12  ? 158.107 177.225 152.333 1.00 117.67 ?  12  VAL S CA  1 
ATOM   7259 C C   . VAL E 5 12  ? 157.677 178.626 151.928 1.00 119.76 ?  12  VAL S C   1 
ATOM   7260 O O   . VAL E 5 12  ? 156.779 179.208 152.546 1.00 124.41 ?  12  VAL S O   1 
ATOM   7261 C CB  . VAL E 5 12  ? 157.083 176.184 151.847 1.00 113.63 ?  12  VAL S CB  1 
ATOM   7262 C CG1 . VAL E 5 12  ? 157.121 176.073 150.337 1.00 113.67 ?  12  VAL S CG1 1 
ATOM   7263 C CG2 . VAL E 5 12  ? 157.358 174.839 152.482 1.00 116.16 ?  12  VAL S CG2 1 
ATOM   7264 N N   . GLN E 5 13  ? 158.323 179.167 150.901 1.00 122.11 ?  13  GLN S N   1 
ATOM   7265 C CA  . GLN E 5 13  ? 157.883 180.424 150.325 1.00 123.56 ?  13  GLN S CA  1 
ATOM   7266 C C   . GLN E 5 13  ? 156.551 180.223 149.603 1.00 124.66 ?  13  GLN S C   1 
ATOM   7267 O O   . GLN E 5 13  ? 156.289 179.144 149.066 1.00 124.07 ?  13  GLN S O   1 
ATOM   7268 C CB  . GLN E 5 13  ? 158.931 180.958 149.352 1.00 125.19 ?  13  GLN S CB  1 
ATOM   7269 C CG  . GLN E 5 13  ? 159.131 182.463 149.398 1.00 125.91 ?  13  GLN S CG  1 
ATOM   7270 C CD  . GLN E 5 13  ? 159.644 182.947 150.740 1.00 130.83 ?  13  GLN S CD  1 
ATOM   7271 O OE1 . GLN E 5 13  ? 160.259 182.193 151.493 1.00 131.71 ?  13  GLN S OE1 1 
ATOM   7272 N NE2 . GLN E 5 13  ? 159.388 184.213 151.047 1.00 127.62 ?  13  GLN S NE2 1 
ATOM   7273 N N   . PRO E 5 14  ? 155.687 181.238 149.589 1.00 115.68 ?  14  PRO S N   1 
ATOM   7274 C CA  . PRO E 5 14  ? 154.409 181.099 148.881 1.00 114.37 ?  14  PRO S CA  1 
ATOM   7275 C C   . PRO E 5 14  ? 154.622 180.778 147.410 1.00 112.27 ?  14  PRO S C   1 
ATOM   7276 O O   . PRO E 5 14  ? 155.526 181.308 146.762 1.00 112.23 ?  14  PRO S O   1 
ATOM   7277 C CB  . PRO E 5 14  ? 153.748 182.467 149.070 1.00 113.22 ?  14  PRO S CB  1 
ATOM   7278 C CG  . PRO E 5 14  ? 154.347 183.001 150.313 1.00 113.24 ?  14  PRO S CG  1 
ATOM   7279 C CD  . PRO E 5 14  ? 155.757 182.491 150.358 1.00 113.05 ?  14  PRO S CD  1 
ATOM   7280 N N   . GLY E 5 15  ? 153.771 179.902 146.885 1.00 110.68 ?  15  GLY S N   1 
ATOM   7281 C CA  . GLY E 5 15  ? 153.937 179.393 145.544 1.00 109.06 ?  15  GLY S CA  1 
ATOM   7282 C C   . GLY E 5 15  ? 154.869 178.209 145.422 1.00 117.05 ?  15  GLY S C   1 
ATOM   7283 O O   . GLY E 5 15  ? 155.105 177.744 144.301 1.00 118.13 ?  15  GLY S O   1 
ATOM   7284 N N   . GLY E 5 16  ? 155.399 177.702 146.530 1.00 118.17 ?  16  GLY S N   1 
ATOM   7285 C CA  . GLY E 5 16  ? 156.301 176.572 146.493 1.00 115.45 ?  16  GLY S CA  1 
ATOM   7286 C C   . GLY E 5 16  ? 155.581 175.273 146.182 1.00 118.73 ?  16  GLY S C   1 
ATOM   7287 O O   . GLY E 5 16  ? 154.360 175.206 146.043 1.00 118.58 ?  16  GLY S O   1 
ATOM   7288 N N   . SER E 5 17  ? 156.373 174.211 146.060 1.00 114.18 ?  17  SER S N   1 
ATOM   7289 C CA  . SER E 5 17  ? 155.858 172.902 145.675 1.00 115.37 ?  17  SER S CA  1 
ATOM   7290 C C   . SER E 5 17  ? 156.469 171.807 146.545 1.00 118.32 ?  17  SER S C   1 
ATOM   7291 O O   . SER E 5 17  ? 156.934 170.778 146.054 1.00 122.75 ?  17  SER S O   1 
ATOM   7292 C CB  . SER E 5 17  ? 156.115 172.635 144.194 1.00 117.24 ?  17  SER S CB  1 
ATOM   7293 O OG  . SER E 5 17  ? 155.222 173.378 143.385 1.00 118.21 ?  17  SER S OG  1 
ATOM   7294 N N   . ARG E 5 18  ? 156.475 172.022 147.857 1.00 114.21 ?  18  ARG S N   1 
ATOM   7295 C CA  . ARG E 5 18  ? 157.034 171.037 148.773 1.00 113.96 ?  18  ARG S CA  1 
ATOM   7296 C C   . ARG E 5 18  ? 156.162 169.787 148.820 1.00 113.25 ?  18  ARG S C   1 
ATOM   7297 O O   . ARG E 5 18  ? 154.934 169.864 148.740 1.00 111.96 ?  18  ARG S O   1 
ATOM   7298 C CB  . ARG E 5 18  ? 157.179 171.643 150.168 1.00 109.74 ?  18  ARG S CB  1 
ATOM   7299 C CG  . ARG E 5 18  ? 157.307 170.633 151.286 1.00 107.21 ?  18  ARG S CG  1 
ATOM   7300 C CD  . ARG E 5 18  ? 158.743 170.510 151.746 1.00 109.79 ?  18  ARG S CD  1 
ATOM   7301 N NE  . ARG E 5 18  ? 159.360 171.812 151.958 1.00 116.67 ?  18  ARG S NE  1 
ATOM   7302 C CZ  . ARG E 5 18  ? 160.531 171.995 152.551 1.00 118.10 ?  18  ARG S CZ  1 
ATOM   7303 N NH1 . ARG E 5 18  ? 161.239 170.978 153.014 1.00 115.30 1  18  ARG S NH1 1 
ATOM   7304 N NH2 . ARG E 5 18  ? 161.004 173.231 152.686 1.00 114.67 ?  18  ARG S NH2 1 
ATOM   7305 N N   . LYS E 5 19  ? 156.807 168.628 148.939 1.00 104.95 ?  19  LYS S N   1 
ATOM   7306 C CA  . LYS E 5 19  ? 156.131 167.339 148.975 1.00 106.43 ?  19  LYS S CA  1 
ATOM   7307 C C   . LYS E 5 19  ? 156.255 166.713 150.357 1.00 108.10 ?  19  LYS S C   1 
ATOM   7308 O O   . LYS E 5 19  ? 157.302 166.810 151.003 1.00 109.75 ?  19  LYS S O   1 
ATOM   7309 C CB  . LYS E 5 19  ? 156.706 166.389 147.923 1.00 101.79 ?  19  LYS S CB  1 
ATOM   7310 C CG  . LYS E 5 19  ? 156.011 165.043 147.851 1.00 99.93  ?  19  LYS S CG  1 
ATOM   7311 C CD  . LYS E 5 19  ? 156.390 164.297 146.589 1.00 105.34 ?  19  LYS S CD  1 
ATOM   7312 C CE  . LYS E 5 19  ? 156.922 162.915 146.906 1.00 108.91 ?  19  LYS S CE  1 
ATOM   7313 N NZ  . LYS E 5 19  ? 158.094 162.983 147.820 1.00 106.37 1  19  LYS S NZ  1 
ATOM   7314 N N   . LEU E 5 20  ? 155.182 166.065 150.801 1.00 97.37  ?  20  LEU S N   1 
ATOM   7315 C CA  . LEU E 5 20  ? 155.101 165.450 152.117 1.00 98.54  ?  20  LEU S CA  1 
ATOM   7316 C C   . LEU E 5 20  ? 155.079 163.934 151.999 1.00 99.98  ?  20  LEU S C   1 
ATOM   7317 O O   . LEU E 5 20  ? 154.407 163.379 151.126 1.00 98.27  ?  20  LEU S O   1 
ATOM   7318 C CB  . LEU E 5 20  ? 153.856 165.930 152.860 1.00 93.15  ?  20  LEU S CB  1 
ATOM   7319 C CG  . LEU E 5 20  ? 154.098 166.838 154.058 1.00 96.32  ?  20  LEU S CG  1 
ATOM   7320 C CD1 . LEU E 5 20  ? 154.575 168.191 153.620 1.00 98.89  ?  20  LEU S CD1 1 
ATOM   7321 C CD2 . LEU E 5 20  ? 152.813 166.970 154.825 1.00 98.95  ?  20  LEU S CD2 1 
ATOM   7322 N N   . SER E 5 21  ? 155.811 163.271 152.890 1.00 97.46  ?  21  SER S N   1 
ATOM   7323 C CA  . SER E 5 21  ? 155.937 161.823 152.890 1.00 99.26  ?  21  SER S CA  1 
ATOM   7324 C C   . SER E 5 21  ? 155.496 161.261 154.232 1.00 101.11 ?  21  SER S C   1 
ATOM   7325 O O   . SER E 5 21  ? 155.665 161.895 155.277 1.00 98.49  ?  21  SER S O   1 
ATOM   7326 C CB  . SER E 5 21  ? 157.377 161.390 152.600 1.00 104.85 ?  21  SER S CB  1 
ATOM   7327 O OG  . SER E 5 21  ? 157.578 161.178 151.215 1.00 105.60 ?  21  SER S OG  1 
ATOM   7328 N N   . CYS E 5 22  ? 154.926 160.060 154.189 1.00 105.70 ?  22  CYS S N   1 
ATOM   7329 C CA  . CYS E 5 22  ? 154.453 159.362 155.382 1.00 103.49 ?  22  CYS S CA  1 
ATOM   7330 C C   . CYS E 5 22  ? 154.743 157.881 155.196 1.00 104.34 ?  22  CYS S C   1 
ATOM   7331 O O   . CYS E 5 22  ? 154.170 157.243 154.309 1.00 102.96 ?  22  CYS S O   1 
ATOM   7332 C CB  . CYS E 5 22  ? 152.963 159.612 155.608 1.00 105.69 ?  22  CYS S CB  1 
ATOM   7333 S SG  . CYS E 5 22  ? 152.088 158.332 156.521 1.00 115.32 ?  22  CYS S SG  1 
ATOM   7334 N N   . SER E 5 23  ? 155.630 157.337 156.022 1.00 103.53 ?  23  SER S N   1 
ATOM   7335 C CA  . SER E 5 23  ? 156.076 155.956 155.892 1.00 103.20 ?  23  SER S CA  1 
ATOM   7336 C C   . SER E 5 23  ? 155.391 155.101 156.949 1.00 103.02 ?  23  SER S C   1 
ATOM   7337 O O   . SER E 5 23  ? 155.492 155.388 158.146 1.00 104.07 ?  23  SER S O   1 
ATOM   7338 C CB  . SER E 5 23  ? 157.594 155.861 156.028 1.00 101.74 ?  23  SER S CB  1 
ATOM   7339 O OG  . SER E 5 23  ? 157.992 156.029 157.375 1.00 108.40 ?  23  SER S OG  1 
ATOM   7340 N N   . ALA E 5 24  ? 154.712 154.050 156.507 1.00 94.37  ?  24  ALA S N   1 
ATOM   7341 C CA  . ALA E 5 24  ? 153.992 153.148 157.390 1.00 89.31  ?  24  ALA S CA  1 
ATOM   7342 C C   . ALA E 5 24  ? 154.841 151.922 157.689 1.00 101.64 ?  24  ALA S C   1 
ATOM   7343 O O   . ALA E 5 24  ? 155.504 151.382 156.801 1.00 110.92 ?  24  ALA S O   1 
ATOM   7344 C CB  . ALA E 5 24  ? 152.667 152.720 156.764 1.00 87.23  ?  24  ALA S CB  1 
ATOM   7345 N N   . SER E 5 25  ? 154.816 151.484 158.945 1.00 96.11  ?  25  SER S N   1 
ATOM   7346 C CA  . SER E 5 25  ? 155.614 150.335 159.359 1.00 94.53  ?  25  SER S CA  1 
ATOM   7347 C C   . SER E 5 25  ? 154.933 149.681 160.550 1.00 94.57  ?  25  SER S C   1 
ATOM   7348 O O   . SER E 5 25  ? 154.980 150.219 161.659 1.00 105.75 ?  25  SER S O   1 
ATOM   7349 C CB  . SER E 5 25  ? 157.035 150.756 159.713 1.00 96.26  ?  25  SER S CB  1 
ATOM   7350 O OG  . SER E 5 25  ? 157.136 151.069 161.090 1.00 98.21  ?  25  SER S OG  1 
ATOM   7351 N N   . GLY E 5 26  ? 154.316 148.525 160.327 1.00 82.87  ?  26  GLY S N   1 
ATOM   7352 C CA  . GLY E 5 26  ? 153.721 147.785 161.420 1.00 87.73  ?  26  GLY S CA  1 
ATOM   7353 C C   . GLY E 5 26  ? 152.328 147.270 161.141 1.00 90.65  ?  26  GLY S C   1 
ATOM   7354 O O   . GLY E 5 26  ? 151.680 146.718 162.034 1.00 91.03  ?  26  GLY S O   1 
ATOM   7355 N N   . PHE E 5 27  ? 151.851 147.442 159.914 1.00 80.49  ?  27  PHE S N   1 
ATOM   7356 C CA  . PHE E 5 27  ? 150.527 146.964 159.544 1.00 77.01  ?  27  PHE S CA  1 
ATOM   7357 C C   . PHE E 5 27  ? 150.487 146.765 158.037 1.00 76.91  ?  27  PHE S C   1 
ATOM   7358 O O   . PHE E 5 27  ? 151.375 147.208 157.307 1.00 82.66  ?  27  PHE S O   1 
ATOM   7359 C CB  . PHE E 5 27  ? 149.429 147.924 160.015 1.00 81.62  ?  27  PHE S CB  1 
ATOM   7360 C CG  . PHE E 5 27  ? 149.468 149.277 159.360 1.00 80.24  ?  27  PHE S CG  1 
ATOM   7361 C CD1 . PHE E 5 27  ? 150.328 150.257 159.815 1.00 73.29  ?  27  PHE S CD1 1 
ATOM   7362 C CD2 . PHE E 5 27  ? 148.630 149.574 158.303 1.00 78.59  ?  27  PHE S CD2 1 
ATOM   7363 C CE1 . PHE E 5 27  ? 150.358 151.494 159.222 1.00 71.95  ?  27  PHE S CE1 1 
ATOM   7364 C CE2 . PHE E 5 27  ? 148.660 150.811 157.706 1.00 74.76  ?  27  PHE S CE2 1 
ATOM   7365 C CZ  . PHE E 5 27  ? 149.523 151.771 158.167 1.00 76.14  ?  27  PHE S CZ  1 
ATOM   7366 N N   . ALA E 5 28  ? 149.440 146.080 157.581 1.00 72.57  ?  28  ALA S N   1 
ATOM   7367 C CA  . ALA E 5 28  ? 149.253 145.790 156.162 1.00 78.13  ?  28  ALA S CA  1 
ATOM   7368 C C   . ALA E 5 28  ? 148.809 147.068 155.459 1.00 84.89  ?  28  ALA S C   1 
ATOM   7369 O O   . ALA E 5 28  ? 147.625 147.304 155.211 1.00 91.79  ?  28  ALA S O   1 
ATOM   7370 C CB  . ALA E 5 28  ? 148.242 144.668 155.973 1.00 73.27  ?  28  ALA S CB  1 
ATOM   7371 N N   . PHE E 5 29  ? 149.795 147.900 155.117 1.00 80.56  ?  29  PHE S N   1 
ATOM   7372 C CA  . PHE E 5 29  ? 149.516 149.214 154.550 1.00 80.54  ?  29  PHE S CA  1 
ATOM   7373 C C   . PHE E 5 29  ? 148.739 149.119 153.245 1.00 77.69  ?  29  PHE S C   1 
ATOM   7374 O O   . PHE E 5 29  ? 147.964 150.022 152.919 1.00 90.03  ?  29  PHE S O   1 
ATOM   7375 C CB  . PHE E 5 29  ? 150.829 149.969 154.338 1.00 78.64  ?  29  PHE S CB  1 
ATOM   7376 C CG  . PHE E 5 29  ? 150.682 151.257 153.582 1.00 81.16  ?  29  PHE S CG  1 
ATOM   7377 C CD1 . PHE E 5 29  ? 150.304 152.414 154.231 1.00 81.90  ?  29  PHE S CD1 1 
ATOM   7378 C CD2 . PHE E 5 29  ? 150.936 151.313 152.225 1.00 86.06  ?  29  PHE S CD2 1 
ATOM   7379 C CE1 . PHE E 5 29  ? 150.176 153.596 153.541 1.00 81.47  ?  29  PHE S CE1 1 
ATOM   7380 C CE2 . PHE E 5 29  ? 150.804 152.493 151.533 1.00 82.39  ?  29  PHE S CE2 1 
ATOM   7381 C CZ  . PHE E 5 29  ? 150.423 153.634 152.191 1.00 80.60  ?  29  PHE S CZ  1 
ATOM   7382 N N   . SER E 5 30  ? 148.924 148.038 152.491 1.00 78.61  ?  30  SER S N   1 
ATOM   7383 C CA  . SER E 5 30  ? 148.273 147.919 151.194 1.00 87.20  ?  30  SER S CA  1 
ATOM   7384 C C   . SER E 5 30  ? 146.762 147.802 151.306 1.00 91.74  ?  30  SER S C   1 
ATOM   7385 O O   . SER E 5 30  ? 146.060 148.112 150.339 1.00 95.69  ?  30  SER S O   1 
ATOM   7386 C CB  . SER E 5 30  ? 148.829 146.713 150.440 1.00 92.31  ?  30  SER S CB  1 
ATOM   7387 O OG  . SER E 5 30  ? 150.174 146.464 150.808 1.00 95.72  ?  30  SER S OG  1 
ATOM   7388 N N   . SER E 5 31  ? 146.245 147.364 152.451 1.00 78.83  ?  31  SER S N   1 
ATOM   7389 C CA  . SER E 5 31  ? 144.815 147.163 152.636 1.00 79.00  ?  31  SER S CA  1 
ATOM   7390 C C   . SER E 5 31  ? 144.154 148.297 153.405 1.00 79.81  ?  31  SER S C   1 
ATOM   7391 O O   . SER E 5 31  ? 142.973 148.194 153.743 1.00 79.94  ?  31  SER S O   1 
ATOM   7392 C CB  . SER E 5 31  ? 144.558 145.835 153.344 1.00 78.66  ?  31  SER S CB  1 
ATOM   7393 O OG  . SER E 5 31  ? 145.415 145.686 154.459 1.00 87.36  ?  31  SER S OG  1 
ATOM   7394 N N   . PHE E 5 32  ? 144.878 149.374 153.678 1.00 75.42  ?  32  PHE S N   1 
ATOM   7395 C CA  . PHE E 5 32  ? 144.372 150.491 154.462 1.00 64.89  ?  32  PHE S CA  1 
ATOM   7396 C C   . PHE E 5 32  ? 144.202 151.702 153.559 1.00 71.00  ?  32  PHE S C   1 
ATOM   7397 O O   . PHE E 5 32  ? 145.155 152.119 152.894 1.00 86.13  ?  32  PHE S O   1 
ATOM   7398 C CB  . PHE E 5 32  ? 145.324 150.824 155.609 1.00 63.74  ?  32  PHE S CB  1 
ATOM   7399 C CG  . PHE E 5 32  ? 145.051 150.059 156.864 1.00 76.15  ?  32  PHE S CG  1 
ATOM   7400 C CD1 . PHE E 5 32  ? 145.576 148.796 157.046 1.00 68.19  ?  32  PHE S CD1 1 
ATOM   7401 C CD2 . PHE E 5 32  ? 144.275 150.603 157.864 1.00 82.47  ?  32  PHE S CD2 1 
ATOM   7402 C CE1 . PHE E 5 32  ? 145.328 148.093 158.198 1.00 70.83  ?  32  PHE S CE1 1 
ATOM   7403 C CE2 . PHE E 5 32  ? 144.024 149.902 159.017 1.00 75.95  ?  32  PHE S CE2 1 
ATOM   7404 C CZ  . PHE E 5 32  ? 144.551 148.647 159.184 1.00 72.38  ?  32  PHE S CZ  1 
ATOM   7405 N N   . GLY E 5 33  ? 142.997 152.262 153.535 1.00 67.60  ?  33  GLY S N   1 
ATOM   7406 C CA  . GLY E 5 33  ? 142.817 153.569 152.935 1.00 63.15  ?  33  GLY S CA  1 
ATOM   7407 C C   . GLY E 5 33  ? 143.449 154.637 153.808 1.00 61.45  ?  33  GLY S C   1 
ATOM   7408 O O   . GLY E 5 33  ? 143.384 154.582 155.035 1.00 81.70  ?  33  GLY S O   1 
ATOM   7409 N N   . MET E 5 34  ? 144.073 155.617 153.168 1.00 54.43  ?  34  MET S N   1 
ATOM   7410 C CA  . MET E 5 34  ? 144.844 156.624 153.880 1.00 63.06  ?  34  MET S CA  1 
ATOM   7411 C C   . MET E 5 34  ? 144.234 158.004 153.688 1.00 70.58  ?  34  MET S C   1 
ATOM   7412 O O   . MET E 5 34  ? 143.629 158.298 152.656 1.00 81.97  ?  34  MET S O   1 
ATOM   7413 C CB  . MET E 5 34  ? 146.298 156.633 153.418 1.00 56.70  ?  34  MET S CB  1 
ATOM   7414 C CG  . MET E 5 34  ? 146.993 155.295 153.539 1.00 70.53  ?  34  MET S CG  1 
ATOM   7415 S SD  . MET E 5 34  ? 147.068 154.674 155.225 1.00 95.97  ?  34  MET S SD  1 
ATOM   7416 C CE  . MET E 5 34  ? 148.265 155.789 155.941 1.00 62.94  ?  34  MET S CE  1 
ATOM   7417 N N   . HIS E 5 35  ? 144.397 158.845 154.704 1.00 69.35  ?  35  HIS S N   1 
ATOM   7418 C CA  . HIS E 5 35  ? 143.898 160.208 154.692 1.00 60.94  ?  35  HIS S CA  1 
ATOM   7419 C C   . HIS E 5 35  ? 145.018 161.159 155.079 1.00 64.30  ?  35  HIS S C   1 
ATOM   7420 O O   . HIS E 5 35  ? 145.971 160.785 155.764 1.00 69.04  ?  35  HIS S O   1 
ATOM   7421 C CB  . HIS E 5 35  ? 142.729 160.408 155.666 1.00 59.19  ?  35  HIS S CB  1 
ATOM   7422 C CG  . HIS E 5 35  ? 141.513 159.603 155.340 1.00 60.23  ?  35  HIS S CG  1 
ATOM   7423 N ND1 . HIS E 5 35  ? 140.370 160.164 154.816 1.00 72.64  ?  35  HIS S ND1 1 
ATOM   7424 C CD2 . HIS E 5 35  ? 141.249 158.286 155.491 1.00 57.42  ?  35  HIS S CD2 1 
ATOM   7425 C CE1 . HIS E 5 35  ? 139.459 159.225 154.645 1.00 64.42  ?  35  HIS S CE1 1 
ATOM   7426 N NE2 . HIS E 5 35  ? 139.968 158.075 155.046 1.00 62.08  ?  35  HIS S NE2 1 
ATOM   7427 N N   . TRP E 5 36  ? 144.893 162.401 154.630 1.00 55.16  ?  36  TRP S N   1 
ATOM   7428 C CA  . TRP E 5 36  ? 145.700 163.500 155.133 1.00 53.80  ?  36  TRP S CA  1 
ATOM   7429 C C   . TRP E 5 36  ? 144.766 164.474 155.827 1.00 66.64  ?  36  TRP S C   1 
ATOM   7430 O O   . TRP E 5 36  ? 143.763 164.892 155.247 1.00 81.49  ?  36  TRP S O   1 
ATOM   7431 C CB  . TRP E 5 36  ? 146.471 164.203 154.012 1.00 65.64  ?  36  TRP S CB  1 
ATOM   7432 C CG  . TRP E 5 36  ? 147.708 163.484 153.579 1.00 65.92  ?  36  TRP S CG  1 
ATOM   7433 C CD1 . TRP E 5 36  ? 147.840 162.680 152.496 1.00 69.29  ?  36  TRP S CD1 1 
ATOM   7434 C CD2 . TRP E 5 36  ? 148.987 163.510 154.217 1.00 65.02  ?  36  TRP S CD2 1 
ATOM   7435 N NE1 . TRP E 5 36  ? 149.116 162.197 152.415 1.00 58.15  ?  36  TRP S NE1 1 
ATOM   7436 C CE2 . TRP E 5 36  ? 149.843 162.691 153.463 1.00 57.94  ?  36  TRP S CE2 1 
ATOM   7437 C CE3 . TRP E 5 36  ? 149.492 164.144 155.351 1.00 77.95  ?  36  TRP S CE3 1 
ATOM   7438 C CZ2 . TRP E 5 36  ? 151.171 162.491 153.805 1.00 62.60  ?  36  TRP S CZ2 1 
ATOM   7439 C CZ3 . TRP E 5 36  ? 150.812 163.940 155.690 1.00 74.75  ?  36  TRP S CZ3 1 
ATOM   7440 C CH2 . TRP E 5 36  ? 151.636 163.122 154.920 1.00 68.69  ?  36  TRP S CH2 1 
ATOM   7441 N N   . VAL E 5 37  ? 145.078 164.812 157.072 1.00 68.36  ?  37  VAL S N   1 
ATOM   7442 C CA  . VAL E 5 37  ? 144.276 165.740 157.857 1.00 65.46  ?  37  VAL S CA  1 
ATOM   7443 C C   . VAL E 5 37  ? 145.214 166.796 158.413 1.00 70.05  ?  37  VAL S C   1 
ATOM   7444 O O   . VAL E 5 37  ? 146.196 166.465 159.084 1.00 86.90  ?  37  VAL S O   1 
ATOM   7445 C CB  . VAL E 5 37  ? 143.519 165.031 158.990 1.00 62.82  ?  37  VAL S CB  1 
ATOM   7446 C CG1 . VAL E 5 37  ? 142.838 166.039 159.884 1.00 62.99  ?  37  VAL S CG1 1 
ATOM   7447 C CG2 . VAL E 5 37  ? 142.508 164.060 158.421 1.00 54.77  ?  37  VAL S CG2 1 
ATOM   7448 N N   . ARG E 5 38  ? 144.922 168.057 158.132 1.00 80.58  ?  38  ARG S N   1 
ATOM   7449 C CA  . ARG E 5 38  ? 145.765 169.157 158.566 1.00 76.72  ?  38  ARG S CA  1 
ATOM   7450 C C   . ARG E 5 38  ? 145.147 169.857 159.766 1.00 82.13  ?  38  ARG S C   1 
ATOM   7451 O O   . ARG E 5 38  ? 143.939 169.795 160.001 1.00 83.60  ?  38  ARG S O   1 
ATOM   7452 C CB  . ARG E 5 38  ? 145.986 170.156 157.429 1.00 78.41  ?  38  ARG S CB  1 
ATOM   7453 C CG  . ARG E 5 38  ? 144.757 170.953 157.059 1.00 85.15  ?  38  ARG S CG  1 
ATOM   7454 C CD  . ARG E 5 38  ? 145.113 172.360 156.628 1.00 86.65  ?  38  ARG S CD  1 
ATOM   7455 N NE  . ARG E 5 38  ? 145.544 172.416 155.239 1.00 85.02  ?  38  ARG S NE  1 
ATOM   7456 C CZ  . ARG E 5 38  ? 144.919 173.098 154.291 1.00 85.35  ?  38  ARG S CZ  1 
ATOM   7457 N NH1 . ARG E 5 38  ? 143.816 173.781 154.544 1.00 87.47  1  38  ARG S NH1 1 
ATOM   7458 N NH2 . ARG E 5 38  ? 145.412 173.095 153.057 1.00 88.01  ?  38  ARG S NH2 1 
ATOM   7459 N N   . GLN E 5 39  ? 146.000 170.522 160.536 1.00 92.88  ?  39  GLN S N   1 
ATOM   7460 C CA  . GLN E 5 39  ? 145.567 171.261 161.712 1.00 86.22  ?  39  GLN S CA  1 
ATOM   7461 C C   . GLN E 5 39  ? 146.305 172.587 161.743 1.00 93.92  ?  39  GLN S C   1 
ATOM   7462 O O   . GLN E 5 39  ? 147.535 172.610 161.829 1.00 103.32 ?  39  GLN S O   1 
ATOM   7463 C CB  . GLN E 5 39  ? 145.829 170.462 162.991 1.00 92.16  ?  39  GLN S CB  1 
ATOM   7464 C CG  . GLN E 5 39  ? 145.993 171.309 164.232 1.00 95.33  ?  39  GLN S CG  1 
ATOM   7465 C CD  . GLN E 5 39  ? 145.442 170.637 165.465 1.00 99.06  ?  39  GLN S CD  1 
ATOM   7466 O OE1 . GLN E 5 39  ? 144.231 170.549 165.648 1.00 94.40  ?  39  GLN S OE1 1 
ATOM   7467 N NE2 . GLN E 5 39  ? 146.331 170.152 166.319 1.00 96.21  ?  39  GLN S NE2 1 
ATOM   7468 N N   . ALA E 5 40  ? 145.557 173.682 161.684 1.00 104.65 ?  40  ALA S N   1 
ATOM   7469 C CA  . ALA E 5 40  ? 146.152 175.003 161.697 1.00 103.22 ?  40  ALA S CA  1 
ATOM   7470 C C   . ALA E 5 40  ? 146.825 175.256 163.045 1.00 108.58 ?  40  ALA S C   1 
ATOM   7471 O O   . ALA E 5 40  ? 146.550 174.556 164.021 1.00 114.08 ?  40  ALA S O   1 
ATOM   7472 C CB  . ALA E 5 40  ? 145.087 176.058 161.416 1.00 106.57 ?  40  ALA S CB  1 
ATOM   7473 N N   . PRO E 5 41  ? 147.736 176.235 163.115 1.00 117.21 ?  41  PRO S N   1 
ATOM   7474 C CA  . PRO E 5 41  ? 148.491 176.445 164.365 1.00 120.49 ?  41  PRO S CA  1 
ATOM   7475 C C   . PRO E 5 41  ? 147.633 176.551 165.616 1.00 122.55 ?  41  PRO S C   1 
ATOM   7476 O O   . PRO E 5 41  ? 148.064 176.101 166.685 1.00 121.47 ?  41  PRO S O   1 
ATOM   7477 C CB  . PRO E 5 41  ? 149.247 177.750 164.090 1.00 115.91 ?  41  PRO S CB  1 
ATOM   7478 C CG  . PRO E 5 41  ? 149.440 177.765 162.627 1.00 117.34 ?  41  PRO S CG  1 
ATOM   7479 C CD  . PRO E 5 41  ? 148.289 177.027 162.002 1.00 114.98 ?  41  PRO S CD  1 
ATOM   7480 N N   . GLU E 5 42  ? 146.436 177.127 165.524 1.00 125.97 ?  42  GLU S N   1 
ATOM   7481 C CA  . GLU E 5 42  ? 145.540 177.184 166.669 1.00 125.30 ?  42  GLU S CA  1 
ATOM   7482 C C   . GLU E 5 42  ? 144.115 176.738 166.371 1.00 122.63 ?  42  GLU S C   1 
ATOM   7483 O O   . GLU E 5 42  ? 143.340 176.564 167.317 1.00 119.51 ?  42  GLU S O   1 
ATOM   7484 C CB  . GLU E 5 42  ? 145.502 178.603 167.254 1.00 124.29 ?  42  GLU S CB  1 
ATOM   7485 C CG  . GLU E 5 42  ? 146.742 178.985 168.042 1.00 126.65 ?  42  GLU S CG  1 
ATOM   7486 C CD  . GLU E 5 42  ? 146.936 178.131 169.279 1.00 128.54 ?  42  GLU S CD  1 
ATOM   7487 O OE1 . GLU E 5 42  ? 146.211 178.348 170.272 1.00 128.16 ?  42  GLU S OE1 1 
ATOM   7488 O OE2 . GLU E 5 42  ? 147.820 177.249 169.262 1.00 125.14 -1 42  GLU S OE2 1 
ATOM   7489 N N   . LYS E 5 43  ? 143.742 176.554 165.107 1.00 116.27 ?  43  LYS S N   1 
ATOM   7490 C CA  . LYS E 5 43  ? 142.399 176.105 164.763 1.00 116.59 ?  43  LYS S CA  1 
ATOM   7491 C C   . LYS E 5 43  ? 142.294 174.593 164.960 1.00 117.19 ?  43  LYS S C   1 
ATOM   7492 O O   . LYS E 5 43  ? 143.184 173.947 165.518 1.00 113.91 ?  43  LYS S O   1 
ATOM   7493 C CB  . LYS E 5 43  ? 142.030 176.506 163.334 1.00 116.02 ?  43  LYS S CB  1 
ATOM   7494 C CG  . LYS E 5 43  ? 142.336 177.933 162.791 1.00 117.34 ?  43  LYS S CG  1 
ATOM   7495 C CD  . LYS E 5 43  ? 142.065 179.142 163.714 1.00 120.75 ?  43  LYS S CD  1 
ATOM   7496 C CE  . LYS E 5 43  ? 143.154 179.471 164.718 1.00 121.26 ?  43  LYS S CE  1 
ATOM   7497 N NZ  . LYS E 5 43  ? 142.686 180.433 165.752 1.00 120.67 1  43  LYS S NZ  1 
ATOM   7498 N N   . GLY E 5 44  ? 141.187 174.013 164.498 1.00 106.18 ?  44  GLY S N   1 
ATOM   7499 C CA  . GLY E 5 44  ? 140.937 172.596 164.632 1.00 101.82 ?  44  GLY S CA  1 
ATOM   7500 C C   . GLY E 5 44  ? 141.337 171.809 163.397 1.00 104.45 ?  44  GLY S C   1 
ATOM   7501 O O   . GLY E 5 44  ? 141.946 172.322 162.457 1.00 111.37 ?  44  GLY S O   1 
ATOM   7502 N N   . LEU E 5 45  ? 140.974 170.530 163.410 1.00 85.66  ?  45  LEU S N   1 
ATOM   7503 C CA  . LEU E 5 45  ? 141.338 169.632 162.326 1.00 81.91  ?  45  LEU S CA  1 
ATOM   7504 C C   . LEU E 5 45  ? 140.532 169.932 161.069 1.00 86.48  ?  45  LEU S C   1 
ATOM   7505 O O   . LEU E 5 45  ? 139.384 170.378 161.127 1.00 87.05  ?  45  LEU S O   1 
ATOM   7506 C CB  . LEU E 5 45  ? 141.122 168.179 162.742 1.00 79.33  ?  45  LEU S CB  1 
ATOM   7507 C CG  . LEU E 5 45  ? 141.595 167.780 164.136 1.00 77.81  ?  45  LEU S CG  1 
ATOM   7508 C CD1 . LEU E 5 45  ? 141.049 166.418 164.502 1.00 72.96  ?  45  LEU S CD1 1 
ATOM   7509 C CD2 . LEU E 5 45  ? 143.104 167.788 164.205 1.00 86.48  ?  45  LEU S CD2 1 
ATOM   7510 N N   . GLU E 5 46  ? 141.150 169.673 159.919 1.00 97.26  ?  46  GLU S N   1 
ATOM   7511 C CA  . GLU E 5 46  ? 140.517 169.874 158.622 1.00 86.65  ?  46  GLU S CA  1 
ATOM   7512 C C   . GLU E 5 46  ? 140.996 168.785 157.678 1.00 87.83  ?  46  GLU S C   1 
ATOM   7513 O O   . GLU E 5 46  ? 142.200 168.650 157.446 1.00 97.85  ?  46  GLU S O   1 
ATOM   7514 C CB  . GLU E 5 46  ? 140.843 171.256 158.053 1.00 83.94  ?  46  GLU S CB  1 
ATOM   7515 C CG  . GLU E 5 46  ? 140.263 171.503 156.677 1.00 91.91  ?  46  GLU S CG  1 
ATOM   7516 C CD  . GLU E 5 46  ? 140.950 172.640 155.952 1.00 100.74 ?  46  GLU S CD  1 
ATOM   7517 O OE1 . GLU E 5 46  ? 141.343 173.621 156.617 1.00 99.42  ?  46  GLU S OE1 1 
ATOM   7518 O OE2 . GLU E 5 46  ? 141.100 172.552 154.717 1.00 104.90 -1 46  GLU S OE2 1 
ATOM   7519 N N   . TRP E 5 47  ? 140.060 168.014 157.140 1.00 67.01  ?  47  TRP S N   1 
ATOM   7520 C CA  . TRP E 5 47  ? 140.398 166.942 156.217 1.00 65.37  ?  47  TRP S CA  1 
ATOM   7521 C C   . TRP E 5 47  ? 140.949 167.514 154.916 1.00 71.07  ?  47  TRP S C   1 
ATOM   7522 O O   . TRP E 5 47  ? 140.513 168.569 154.453 1.00 89.49  ?  47  TRP S O   1 
ATOM   7523 C CB  . TRP E 5 47  ? 139.162 166.092 155.954 1.00 66.77  ?  47  TRP S CB  1 
ATOM   7524 C CG  . TRP E 5 47  ? 139.340 165.019 154.956 1.00 62.48  ?  47  TRP S CG  1 
ATOM   7525 C CD1 . TRP E 5 47  ? 139.985 163.839 155.133 1.00 68.27  ?  47  TRP S CD1 1 
ATOM   7526 C CD2 . TRP E 5 47  ? 138.837 165.007 153.621 1.00 65.37  ?  47  TRP S CD2 1 
ATOM   7527 N NE1 . TRP E 5 47  ? 139.927 163.093 153.986 1.00 66.04  ?  47  TRP S NE1 1 
ATOM   7528 C CE2 . TRP E 5 47  ? 139.226 163.791 153.041 1.00 63.85  ?  47  TRP S CE2 1 
ATOM   7529 C CE3 . TRP E 5 47  ? 138.098 165.911 152.856 1.00 69.90  ?  47  TRP S CE3 1 
ATOM   7530 C CZ2 . TRP E 5 47  ? 138.904 163.454 151.736 1.00 72.28  ?  47  TRP S CZ2 1 
ATOM   7531 C CZ3 . TRP E 5 47  ? 137.781 165.575 151.564 1.00 73.03  ?  47  TRP S CZ3 1 
ATOM   7532 C CH2 . TRP E 5 47  ? 138.182 164.358 151.015 1.00 76.86  ?  47  TRP S CH2 1 
ATOM   7533 N N   . VAL E 5 48  ? 141.918 166.814 154.326 1.00 67.29  ?  48  VAL S N   1 
ATOM   7534 C CA  . VAL E 5 48  ? 142.610 167.319 153.145 1.00 60.59  ?  48  VAL S CA  1 
ATOM   7535 C C   . VAL E 5 48  ? 142.391 166.406 151.947 1.00 64.22  ?  48  VAL S C   1 
ATOM   7536 O O   . VAL E 5 48  ? 141.817 166.824 150.938 1.00 84.72  ?  48  VAL S O   1 
ATOM   7537 C CB  . VAL E 5 48  ? 144.114 167.495 153.422 1.00 68.21  ?  48  VAL S CB  1 
ATOM   7538 C CG1 . VAL E 5 48  ? 144.873 167.680 152.128 1.00 68.83  ?  48  VAL S CG1 1 
ATOM   7539 C CG2 . VAL E 5 48  ? 144.343 168.673 154.337 1.00 71.88  ?  48  VAL S CG2 1 
ATOM   7540 N N   . ALA E 5 49  ? 142.843 165.158 152.041 1.00 62.82  ?  49  ALA S N   1 
ATOM   7541 C CA  . ALA E 5 49  ? 142.804 164.260 150.898 1.00 55.60  ?  49  ALA S CA  1 
ATOM   7542 C C   . ALA E 5 49  ? 142.683 162.824 151.376 1.00 69.41  ?  49  ALA S C   1 
ATOM   7543 O O   . ALA E 5 49  ? 143.034 162.494 152.509 1.00 91.29  ?  49  ALA S O   1 
ATOM   7544 C CB  . ALA E 5 49  ? 144.047 164.419 150.021 1.00 71.19  ?  49  ALA S CB  1 
ATOM   7545 N N   . TYR E 5 50  ? 142.196 161.966 150.484 1.00 64.64  ?  50  TYR S N   1 
ATOM   7546 C CA  . TYR E 5 50  ? 141.972 160.561 150.789 1.00 62.73  ?  50  TYR S CA  1 
ATOM   7547 C C   . TYR E 5 50  ? 142.310 159.727 149.567 1.00 74.31  ?  50  TYR S C   1 
ATOM   7548 O O   . TYR E 5 50  ? 141.913 160.076 148.454 1.00 90.18  ?  50  TYR S O   1 
ATOM   7549 C CB  . TYR E 5 50  ? 140.519 160.322 151.204 1.00 61.20  ?  50  TYR S CB  1 
ATOM   7550 C CG  . TYR E 5 50  ? 140.029 158.904 151.031 1.00 61.22  ?  50  TYR S CG  1 
ATOM   7551 C CD1 . TYR E 5 50  ? 140.454 157.894 151.876 1.00 72.85  ?  50  TYR S CD1 1 
ATOM   7552 C CD2 . TYR E 5 50  ? 139.127 158.581 150.037 1.00 59.13  ?  50  TYR S CD2 1 
ATOM   7553 C CE1 . TYR E 5 50  ? 140.001 156.607 151.733 1.00 70.53  ?  50  TYR S CE1 1 
ATOM   7554 C CE2 . TYR E 5 50  ? 138.669 157.294 149.886 1.00 65.56  ?  50  TYR S CE2 1 
ATOM   7555 C CZ  . TYR E 5 50  ? 139.110 156.312 150.737 1.00 71.30  ?  50  TYR S CZ  1 
ATOM   7556 O OH  . TYR E 5 50  ? 138.656 155.027 150.590 1.00 75.65  ?  50  TYR S OH  1 
ATOM   7557 N N   . ILE E 5 51  ? 143.044 158.637 149.769 1.00 68.73  ?  51  ILE S N   1 
ATOM   7558 C CA  . ILE E 5 51  ? 143.315 157.670 148.714 1.00 62.96  ?  51  ILE S CA  1 
ATOM   7559 C C   . ILE E 5 51  ? 143.014 156.280 149.255 1.00 67.90  ?  51  ILE S C   1 
ATOM   7560 O O   . ILE E 5 51  ? 143.517 155.897 150.315 1.00 85.46  ?  51  ILE S O   1 
ATOM   7561 C CB  . ILE E 5 51  ? 144.763 157.769 148.198 1.00 62.82  ?  51  ILE S CB  1 
ATOM   7562 C CG1 . ILE E 5 51  ? 145.027 156.701 147.141 1.00 69.98  ?  51  ILE S CG1 1 
ATOM   7563 C CG2 . ILE E 5 51  ? 145.761 157.671 149.331 1.00 61.26  ?  51  ILE S CG2 1 
ATOM   7564 C CD1 . ILE E 5 51  ? 146.099 157.080 146.163 1.00 73.91  ?  51  ILE S CD1 1 
ATOM   7565 N N   . SER E 5 52  ? 142.179 155.534 148.540 1.00 67.27  ?  52  SER S N   1 
ATOM   7566 C CA  . SER E 5 52  ? 141.742 154.236 149.020 1.00 74.14  ?  52  SER S CA  1 
ATOM   7567 C C   . SER E 5 52  ? 142.831 153.190 148.810 1.00 86.36  ?  52  SER S C   1 
ATOM   7568 O O   . SER E 5 52  ? 143.842 153.426 148.147 1.00 97.53  ?  52  SER S O   1 
ATOM   7569 C CB  . SER E 5 52  ? 140.459 153.807 148.317 1.00 77.68  ?  52  SER S CB  1 
ATOM   7570 O OG  . SER E 5 52  ? 140.616 153.826 146.914 1.00 84.81  ?  52  SER S OG  1 
ATOM   7571 N N   . SER E 5 53  ? 142.618 152.018 149.401 1.00 90.46  ?  53  SER S N   1 
ATOM   7572 C CA  . SER E 5 53  ? 143.514 150.896 149.169 1.00 90.65  ?  53  SER S CA  1 
ATOM   7573 C C   . SER E 5 53  ? 143.404 150.452 147.717 1.00 100.01 ?  53  SER S C   1 
ATOM   7574 O O   . SER E 5 53  ? 142.303 150.231 147.205 1.00 99.97  ?  53  SER S O   1 
ATOM   7575 C CB  . SER E 5 53  ? 143.177 149.744 150.109 1.00 90.78  ?  53  SER S CB  1 
ATOM   7576 O OG  . SER E 5 53  ? 142.017 149.061 149.674 1.00 98.89  ?  53  SER S OG  1 
ATOM   7577 N N   . GLY E 5 54  ? 144.546 150.319 147.052 1.00 98.54  ?  54  GLY S N   1 
ATOM   7578 C CA  . GLY E 5 54  ? 144.562 150.091 145.627 1.00 98.37  ?  54  GLY S CA  1 
ATOM   7579 C C   . GLY E 5 54  ? 144.491 151.344 144.786 1.00 103.52 ?  54  GLY S C   1 
ATOM   7580 O O   . GLY E 5 54  ? 144.530 151.244 143.554 1.00 105.35 ?  54  GLY S O   1 
ATOM   7581 N N   . SER E 5 55  ? 144.372 152.516 145.410 1.00 94.28  ?  55  SER S N   1 
ATOM   7582 C CA  . SER E 5 55  ? 144.396 153.815 144.740 1.00 86.89  ?  55  SER S CA  1 
ATOM   7583 C C   . SER E 5 55  ? 143.261 153.983 143.739 1.00 90.97  ?  55  SER S C   1 
ATOM   7584 O O   . SER E 5 55  ? 143.327 154.850 142.865 1.00 94.89  ?  55  SER S O   1 
ATOM   7585 C CB  . SER E 5 55  ? 145.742 154.054 144.051 1.00 90.08  ?  55  SER S CB  1 
ATOM   7586 O OG  . SER E 5 55  ? 146.803 153.548 144.838 1.00 90.45  ?  55  SER S OG  1 
ATOM   7587 N N   . GLY E 5 56  ? 142.206 153.177 143.851 1.00 86.19  ?  56  GLY S N   1 
ATOM   7588 C CA  . GLY E 5 56  ? 141.106 153.275 142.912 1.00 85.61  ?  56  GLY S CA  1 
ATOM   7589 C C   . GLY E 5 56  ? 140.217 154.481 143.118 1.00 91.13  ?  56  GLY S C   1 
ATOM   7590 O O   . GLY E 5 56  ? 139.528 154.895 142.182 1.00 91.66  ?  56  GLY S O   1 
ATOM   7591 N N   . THR E 5 57  ? 140.214 155.053 144.319 1.00 90.27  ?  57  THR S N   1 
ATOM   7592 C CA  . THR E 5 57  ? 139.377 156.199 144.640 1.00 83.71  ?  57  THR S CA  1 
ATOM   7593 C C   . THR E 5 57  ? 140.217 157.248 145.346 1.00 80.44  ?  57  THR S C   1 
ATOM   7594 O O   . THR E 5 57  ? 140.949 156.930 146.287 1.00 89.85  ?  57  THR S O   1 
ATOM   7595 C CB  . THR E 5 57  ? 138.194 155.794 145.520 1.00 82.98  ?  57  THR S CB  1 
ATOM   7596 O OG1 . THR E 5 57  ? 137.455 154.751 144.875 1.00 89.36  ?  57  THR S OG1 1 
ATOM   7597 C CG2 . THR E 5 57  ? 137.281 156.973 145.759 1.00 76.86  ?  57  THR S CG2 1 
ATOM   7598 N N   . ILE E 5 58  ? 140.115 158.491 144.888 1.00 73.56  ?  58  ILE S N   1 
ATOM   7599 C CA  . ILE E 5 58  ? 140.835 159.615 145.469 1.00 68.36  ?  58  ILE S CA  1 
ATOM   7600 C C   . ILE E 5 58  ? 139.860 160.767 145.653 1.00 74.50  ?  58  ILE S C   1 
ATOM   7601 O O   . ILE E 5 58  ? 139.057 161.059 144.761 1.00 88.78  ?  58  ILE S O   1 
ATOM   7602 C CB  . ILE E 5 58  ? 142.023 160.049 144.589 1.00 74.38  ?  58  ILE S CB  1 
ATOM   7603 C CG1 . ILE E 5 58  ? 142.989 158.887 144.379 1.00 74.83  ?  58  ILE S CG1 1 
ATOM   7604 C CG2 . ILE E 5 58  ? 142.743 161.214 145.218 1.00 68.81  ?  58  ILE S CG2 1 
ATOM   7605 C CD1 . ILE E 5 58  ? 144.336 159.308 143.858 1.00 80.41  ?  58  ILE S CD1 1 
ATOM   7606 N N   . TYR E 5 59  ? 139.923 161.416 146.811 1.00 70.99  ?  59  TYR S N   1 
ATOM   7607 C CA  . TYR E 5 59  ? 139.098 162.577 147.101 1.00 65.03  ?  59  TYR S CA  1 
ATOM   7608 C C   . TYR E 5 59  ? 139.970 163.693 147.646 1.00 75.64  ?  59  TYR S C   1 
ATOM   7609 O O   . TYR E 5 59  ? 140.977 163.445 148.311 1.00 88.07  ?  59  TYR S O   1 
ATOM   7610 C CB  . TYR E 5 59  ? 137.996 162.255 148.109 1.00 71.13  ?  59  TYR S CB  1 
ATOM   7611 C CG  . TYR E 5 59  ? 136.947 161.305 147.597 1.00 74.46  ?  59  TYR S CG  1 
ATOM   7612 C CD1 . TYR E 5 59  ? 136.270 161.559 146.418 1.00 80.73  ?  59  TYR S CD1 1 
ATOM   7613 C CD2 . TYR E 5 59  ? 136.630 160.155 148.295 1.00 79.05  ?  59  TYR S CD2 1 
ATOM   7614 C CE1 . TYR E 5 59  ? 135.310 160.692 145.949 1.00 86.73  ?  59  TYR S CE1 1 
ATOM   7615 C CE2 . TYR E 5 59  ? 135.673 159.284 147.834 1.00 79.02  ?  59  TYR S CE2 1 
ATOM   7616 C CZ  . TYR E 5 59  ? 135.017 159.556 146.661 1.00 88.13  ?  59  TYR S CZ  1 
ATOM   7617 O OH  . TYR E 5 59  ? 134.060 158.686 146.199 1.00 88.81  ?  59  TYR S OH  1 
ATOM   7618 N N   . TYR E 5 60  ? 139.573 164.928 147.360 1.00 71.45  ?  60  TYR S N   1 
ATOM   7619 C CA  . TYR E 5 60  ? 140.276 166.107 147.837 1.00 76.77  ?  60  TYR S CA  1 
ATOM   7620 C C   . TYR E 5 60  ? 139.282 167.077 148.452 1.00 76.06  ?  60  TYR S C   1 
ATOM   7621 O O   . TYR E 5 60  ? 138.103 167.091 148.094 1.00 79.95  ?  60  TYR S O   1 
ATOM   7622 C CB  . TYR E 5 60  ? 141.036 166.816 146.714 1.00 76.40  ?  60  TYR S CB  1 
ATOM   7623 C CG  . TYR E 5 60  ? 142.175 166.025 146.131 1.00 75.22  ?  60  TYR S CG  1 
ATOM   7624 C CD1 . TYR E 5 60  ? 143.414 166.000 146.746 1.00 65.44  ?  60  TYR S CD1 1 
ATOM   7625 C CD2 . TYR E 5 60  ? 142.013 165.310 144.959 1.00 78.02  ?  60  TYR S CD2 1 
ATOM   7626 C CE1 . TYR E 5 60  ? 144.453 165.280 146.213 1.00 71.00  ?  60  TYR S CE1 1 
ATOM   7627 C CE2 . TYR E 5 60  ? 143.047 164.590 144.420 1.00 81.21  ?  60  TYR S CE2 1 
ATOM   7628 C CZ  . TYR E 5 60  ? 144.264 164.577 145.050 1.00 82.23  ?  60  TYR S CZ  1 
ATOM   7629 O OH  . TYR E 5 60  ? 145.299 163.855 144.508 1.00 84.49  ?  60  TYR S OH  1 
ATOM   7630 N N   . ALA E 5 61  ? 139.768 167.881 149.389 1.00 80.15  ?  61  ALA S N   1 
ATOM   7631 C CA  . ALA E 5 61  ? 138.971 168.988 149.887 1.00 84.61  ?  61  ALA S CA  1 
ATOM   7632 C C   . ALA E 5 61  ? 138.908 170.090 148.838 1.00 95.03  ?  61  ALA S C   1 
ATOM   7633 O O   . ALA E 5 61  ? 139.824 170.261 148.031 1.00 107.35 ?  61  ALA S O   1 
ATOM   7634 C CB  . ALA E 5 61  ? 139.556 169.530 151.187 1.00 81.86  ?  61  ALA S CB  1 
ATOM   7635 N N   . ASP E 5 62  ? 137.807 170.842 148.851 1.00 106.08 ?  62  ASP S N   1 
ATOM   7636 C CA  . ASP E 5 62  ? 137.642 171.919 147.883 1.00 109.40 ?  62  ASP S CA  1 
ATOM   7637 C C   . ASP E 5 62  ? 138.706 172.996 148.031 1.00 107.79 ?  62  ASP S C   1 
ATOM   7638 O O   . ASP E 5 62  ? 138.968 173.728 147.072 1.00 109.63 ?  62  ASP S O   1 
ATOM   7639 C CB  . ASP E 5 62  ? 136.254 172.542 148.021 1.00 112.88 ?  62  ASP S CB  1 
ATOM   7640 C CG  . ASP E 5 62  ? 135.220 171.858 147.150 1.00 116.91 ?  62  ASP S CG  1 
ATOM   7641 O OD1 . ASP E 5 62  ? 135.594 171.336 146.079 1.00 115.84 ?  62  ASP S OD1 1 
ATOM   7642 O OD2 . ASP E 5 62  ? 134.033 171.843 147.537 1.00 113.47 -1 62  ASP S OD2 1 
ATOM   7643 N N   . THR E 5 63  ? 139.324 173.110 149.206 1.00 100.21 ?  63  THR S N   1 
ATOM   7644 C CA  . THR E 5 63  ? 140.344 174.128 149.416 1.00 100.52 ?  63  THR S CA  1 
ATOM   7645 C C   . THR E 5 63  ? 141.660 173.775 148.737 1.00 105.14 ?  63  THR S C   1 
ATOM   7646 O O   . THR E 5 63  ? 142.431 174.674 148.390 1.00 110.87 ?  63  THR S O   1 
ATOM   7647 C CB  . THR E 5 63  ? 140.576 174.338 150.911 1.00 104.90 ?  63  THR S CB  1 
ATOM   7648 O OG1 . THR E 5 63  ? 139.325 174.263 151.603 1.00 105.49 ?  63  THR S OG1 1 
ATOM   7649 C CG2 . THR E 5 63  ? 141.201 175.696 151.164 1.00 106.45 ?  63  THR S CG2 1 
ATOM   7650 N N   . VAL E 5 64  ? 141.937 172.487 148.542 1.00 99.96  ?  64  VAL S N   1 
ATOM   7651 C CA  . VAL E 5 64  ? 143.198 172.035 147.971 1.00 93.19  ?  64  VAL S CA  1 
ATOM   7652 C C   . VAL E 5 64  ? 143.020 171.309 146.650 1.00 100.16 ?  64  VAL S C   1 
ATOM   7653 O O   . VAL E 5 64  ? 144.014 170.882 146.058 1.00 110.98 ?  64  VAL S O   1 
ATOM   7654 C CB  . VAL E 5 64  ? 143.976 171.146 148.962 1.00 90.50  ?  64  VAL S CB  1 
ATOM   7655 C CG1 . VAL E 5 64  ? 144.037 171.799 150.325 1.00 89.22  ?  64  VAL S CG1 1 
ATOM   7656 C CG2 . VAL E 5 64  ? 143.337 169.775 149.055 1.00 90.53  ?  64  VAL S CG2 1 
ATOM   7657 N N   . LYS E 5 65  ? 141.789 171.145 146.173 1.00 96.85  ?  65  LYS S N   1 
ATOM   7658 C CA  . LYS E 5 65  ? 141.566 170.448 144.914 1.00 92.77  ?  65  LYS S CA  1 
ATOM   7659 C C   . LYS E 5 65  ? 142.225 171.201 143.768 1.00 99.34  ?  65  LYS S C   1 
ATOM   7660 O O   . LYS E 5 65  ? 142.085 172.420 143.646 1.00 97.94  ?  65  LYS S O   1 
ATOM   7661 C CB  . LYS E 5 65  ? 140.070 170.294 144.651 1.00 95.85  ?  65  LYS S CB  1 
ATOM   7662 C CG  . LYS E 5 65  ? 139.740 169.516 143.390 1.00 98.36  ?  65  LYS S CG  1 
ATOM   7663 C CD  . LYS E 5 65  ? 138.757 168.393 143.673 1.00 102.87 ?  65  LYS S CD  1 
ATOM   7664 C CE  . LYS E 5 65  ? 137.569 168.888 144.480 1.00 104.71 ?  65  LYS S CE  1 
ATOM   7665 N NZ  . LYS E 5 65  ? 136.741 167.767 145.000 1.00 98.84  1  65  LYS S NZ  1 
ATOM   7666 N N   . GLY E 5 66  ? 142.950 170.466 142.928 1.00 104.09 ?  66  GLY S N   1 
ATOM   7667 C CA  . GLY E 5 66  ? 143.676 171.040 141.823 1.00 102.05 ?  66  GLY S CA  1 
ATOM   7668 C C   . GLY E 5 66  ? 145.087 171.478 142.148 1.00 104.33 ?  66  GLY S C   1 
ATOM   7669 O O   . GLY E 5 66  ? 145.882 171.689 141.228 1.00 108.79 ?  66  GLY S O   1 
ATOM   7670 N N   . ARG E 5 67  ? 145.423 171.613 143.429 1.00 98.56  ?  67  ARG S N   1 
ATOM   7671 C CA  . ARG E 5 67  ? 146.756 172.014 143.851 1.00 95.38  ?  67  ARG S CA  1 
ATOM   7672 C C   . ARG E 5 67  ? 147.514 170.919 144.579 1.00 101.34 ?  67  ARG S C   1 
ATOM   7673 O O   . ARG E 5 67  ? 148.742 170.870 144.487 1.00 100.80 ?  67  ARG S O   1 
ATOM   7674 C CB  . ARG E 5 67  ? 146.676 173.246 144.759 1.00 90.22  ?  67  ARG S CB  1 
ATOM   7675 C CG  . ARG E 5 67  ? 145.600 174.229 144.352 1.00 93.56  ?  67  ARG S CG  1 
ATOM   7676 C CD  . ARG E 5 67  ? 145.382 175.293 145.410 1.00 98.57  ?  67  ARG S CD  1 
ATOM   7677 N NE  . ARG E 5 67  ? 146.506 175.397 146.330 1.00 100.08 ?  67  ARG S NE  1 
ATOM   7678 C CZ  . ARG E 5 67  ? 146.398 175.346 147.650 1.00 99.26  ?  67  ARG S CZ  1 
ATOM   7679 N NH1 . ARG E 5 67  ? 145.227 175.185 148.242 1.00 94.82  1  67  ARG S NH1 1 
ATOM   7680 N NH2 . ARG E 5 67  ? 147.493 175.462 148.394 1.00 99.52  ?  67  ARG S NH2 1 
ATOM   7681 N N   . PHE E 5 68  ? 146.816 170.044 145.296 1.00 93.14  ?  68  PHE S N   1 
ATOM   7682 C CA  . PHE E 5 68  ? 147.433 168.952 146.030 1.00 89.00  ?  68  PHE S CA  1 
ATOM   7683 C C   . PHE E 5 68  ? 147.267 167.655 145.250 1.00 92.91  ?  68  PHE S C   1 
ATOM   7684 O O   . PHE E 5 68  ? 146.300 167.478 144.508 1.00 95.34  ?  68  PHE S O   1 
ATOM   7685 C CB  . PHE E 5 68  ? 146.809 168.795 147.419 1.00 88.08  ?  68  PHE S CB  1 
ATOM   7686 C CG  . PHE E 5 68  ? 147.231 169.845 148.410 1.00 87.18  ?  68  PHE S CG  1 
ATOM   7687 C CD1 . PHE E 5 68  ? 147.709 171.071 147.993 1.00 92.00  ?  68  PHE S CD1 1 
ATOM   7688 C CD2 . PHE E 5 68  ? 147.134 169.602 149.765 1.00 92.91  ?  68  PHE S CD2 1 
ATOM   7689 C CE1 . PHE E 5 68  ? 148.083 172.029 148.907 1.00 92.14  ?  68  PHE S CE1 1 
ATOM   7690 C CE2 . PHE E 5 68  ? 147.509 170.558 150.681 1.00 91.48  ?  68  PHE S CE2 1 
ATOM   7691 C CZ  . PHE E 5 68  ? 147.985 171.771 150.251 1.00 87.28  ?  68  PHE S CZ  1 
ATOM   7692 N N   . THR E 5 69  ? 148.226 166.749 145.421 1.00 91.93  ?  69  THR S N   1 
ATOM   7693 C CA  . THR E 5 69  ? 148.167 165.437 144.788 1.00 87.39  ?  69  THR S CA  1 
ATOM   7694 C C   . THR E 5 69  ? 148.592 164.386 145.799 1.00 92.31  ?  69  THR S C   1 
ATOM   7695 O O   . THR E 5 69  ? 149.728 164.410 146.281 1.00 93.75  ?  69  THR S O   1 
ATOM   7696 C CB  . THR E 5 69  ? 149.058 165.372 143.546 1.00 94.00  ?  69  THR S CB  1 
ATOM   7697 O OG1 . THR E 5 69  ? 148.719 166.442 142.657 1.00 99.48  ?  69  THR S OG1 1 
ATOM   7698 C CG2 . THR E 5 69  ? 148.862 164.051 142.825 1.00 93.27  ?  69  THR S CG2 1 
ATOM   7699 N N   . ILE E 5 70  ? 147.686 163.469 146.110 1.00 88.82  ?  70  ILE S N   1 
ATOM   7700 C CA  . ILE E 5 70  ? 147.945 162.383 147.045 1.00 89.56  ?  70  ILE S CA  1 
ATOM   7701 C C   . ILE E 5 70  ? 148.196 161.113 146.248 1.00 90.92  ?  70  ILE S C   1 
ATOM   7702 O O   . ILE E 5 70  ? 147.612 160.898 145.180 1.00 90.31  ?  70  ILE S O   1 
ATOM   7703 C CB  . ILE E 5 70  ? 146.776 162.211 148.040 1.00 85.78  ?  70  ILE S CB  1 
ATOM   7704 C CG1 . ILE E 5 70  ? 147.188 161.336 149.220 1.00 81.31  ?  70  ILE S CG1 1 
ATOM   7705 C CG2 . ILE E 5 70  ? 145.560 161.625 147.360 1.00 80.14  ?  70  ILE S CG2 1 
ATOM   7706 C CD1 . ILE E 5 70  ? 146.074 161.096 150.194 1.00 83.18  ?  70  ILE S CD1 1 
ATOM   7707 N N   . SER E 5 71  ? 149.090 160.270 146.756 1.00 90.52  ?  71  SER S N   1 
ATOM   7708 C CA  . SER E 5 71  ? 149.420 159.034 146.064 1.00 86.71  ?  71  SER S CA  1 
ATOM   7709 C C   . SER E 5 71  ? 150.091 158.074 147.032 1.00 92.48  ?  71  SER S C   1 
ATOM   7710 O O   . SER E 5 71  ? 150.883 158.491 147.879 1.00 90.80  ?  71  SER S O   1 
ATOM   7711 C CB  . SER E 5 71  ? 150.338 159.299 144.868 1.00 85.41  ?  71  SER S CB  1 
ATOM   7712 O OG  . SER E 5 71  ? 151.489 160.021 145.267 1.00 89.86  ?  71  SER S OG  1 
ATOM   7713 N N   . ARG E 5 72  ? 149.768 156.794 146.897 1.00 91.86  ?  72  ARG S N   1 
ATOM   7714 C CA  . ARG E 5 72  ? 150.434 155.743 147.645 1.00 85.64  ?  72  ARG S CA  1 
ATOM   7715 C C   . ARG E 5 72  ? 151.572 155.168 146.819 1.00 92.73  ?  72  ARG S C   1 
ATOM   7716 O O   . ARG E 5 72  ? 151.610 155.296 145.594 1.00 102.05 ?  72  ARG S O   1 
ATOM   7717 C CB  . ARG E 5 72  ? 149.468 154.614 148.003 1.00 84.08  ?  72  ARG S CB  1 
ATOM   7718 C CG  . ARG E 5 72  ? 148.084 155.056 148.383 1.00 93.93  ?  72  ARG S CG  1 
ATOM   7719 C CD  . ARG E 5 72  ? 147.129 153.883 148.366 1.00 87.37  ?  72  ARG S CD  1 
ATOM   7720 N NE  . ARG E 5 72  ? 147.517 152.866 149.331 1.00 88.30  ?  72  ARG S NE  1 
ATOM   7721 C CZ  . ARG E 5 72  ? 146.950 152.715 150.518 1.00 82.08  ?  72  ARG S CZ  1 
ATOM   7722 N NH1 . ARG E 5 72  ? 145.943 153.477 150.902 1.00 81.67  1  72  ARG S NH1 1 
ATOM   7723 N NH2 . ARG E 5 72  ? 147.403 151.775 151.339 1.00 88.61  ?  72  ARG S NH2 1 
ATOM   7724 N N   . ASP E 5 73  ? 152.504 154.515 147.504 1.00 108.37 ?  73  ASP S N   1 
ATOM   7725 C CA  . ASP E 5 73  ? 153.501 153.680 146.834 1.00 110.42 ?  73  ASP S CA  1 
ATOM   7726 C C   . ASP E 5 73  ? 153.650 152.436 147.707 1.00 108.94 ?  73  ASP S C   1 
ATOM   7727 O O   . ASP E 5 73  ? 154.460 152.401 148.636 1.00 111.01 ?  73  ASP S O   1 
ATOM   7728 C CB  . ASP E 5 73  ? 154.810 154.427 146.622 1.00 115.14 ?  73  ASP S CB  1 
ATOM   7729 C CG  . ASP E 5 73  ? 155.915 153.536 146.105 1.00 118.20 ?  73  ASP S CG  1 
ATOM   7730 O OD1 . ASP E 5 73  ? 155.658 152.734 145.183 1.00 116.03 ?  73  ASP S OD1 1 
ATOM   7731 O OD2 . ASP E 5 73  ? 157.056 153.685 146.575 1.00 114.73 -1 73  ASP S OD2 1 
ATOM   7732 N N   . ASP E 5 74  ? 152.844 151.423 147.396 1.00 97.36  ?  74  ASP S N   1 
ATOM   7733 C CA  . ASP E 5 74  ? 152.676 150.282 148.292 1.00 103.53 ?  74  ASP S CA  1 
ATOM   7734 C C   . ASP E 5 74  ? 153.941 149.472 148.563 1.00 110.57 ?  74  ASP S C   1 
ATOM   7735 O O   . ASP E 5 74  ? 154.142 149.089 149.728 1.00 109.50 ?  74  ASP S O   1 
ATOM   7736 C CB  . ASP E 5 74  ? 151.569 149.374 147.746 1.00 105.02 ?  74  ASP S CB  1 
ATOM   7737 C CG  . ASP E 5 74  ? 150.187 149.930 148.001 1.00 104.05 ?  74  ASP S CG  1 
ATOM   7738 O OD1 . ASP E 5 74  ? 150.071 150.895 148.781 1.00 105.21 ?  74  ASP S OD1 1 
ATOM   7739 O OD2 . ASP E 5 74  ? 149.214 149.404 147.426 1.00 105.18 -1 74  ASP S OD2 1 
ATOM   7740 N N   . PRO E 5 75  ? 154.805 149.158 147.582 1.00 120.01 ?  75  PRO S N   1 
ATOM   7741 C CA  . PRO E 5 75  ? 155.886 148.190 147.850 1.00 112.92 ?  75  PRO S CA  1 
ATOM   7742 C C   . PRO E 5 75  ? 156.749 148.491 149.068 1.00 117.30 ?  75  PRO S C   1 
ATOM   7743 O O   . PRO E 5 75  ? 157.180 147.543 149.734 1.00 119.12 ?  75  PRO S O   1 
ATOM   7744 C CB  . PRO E 5 75  ? 156.710 148.221 146.553 1.00 113.74 ?  75  PRO S CB  1 
ATOM   7745 C CG  . PRO E 5 75  ? 156.158 149.341 145.732 1.00 118.19 ?  75  PRO S CG  1 
ATOM   7746 C CD  . PRO E 5 75  ? 154.747 149.488 146.150 1.00 119.42 ?  75  PRO S CD  1 
ATOM   7747 N N   . LYS E 5 76  ? 157.020 149.755 149.394 1.00 112.91 ?  76  LYS S N   1 
ATOM   7748 C CA  . LYS E 5 76  ? 157.745 150.054 150.626 1.00 119.07 ?  76  LYS S CA  1 
ATOM   7749 C C   . LYS E 5 76  ? 156.941 150.953 151.564 1.00 118.59 ?  76  LYS S C   1 
ATOM   7750 O O   . LYS E 5 76  ? 157.499 151.581 152.466 1.00 114.53 ?  76  LYS S O   1 
ATOM   7751 C CB  . LYS E 5 76  ? 159.129 150.640 150.335 1.00 119.15 ?  76  LYS S CB  1 
ATOM   7752 C CG  . LYS E 5 76  ? 159.203 152.128 150.080 1.00 116.59 ?  76  LYS S CG  1 
ATOM   7753 C CD  . LYS E 5 76  ? 158.689 152.456 148.711 1.00 114.77 ?  76  LYS S CD  1 
ATOM   7754 C CE  . LYS E 5 76  ? 159.749 152.178 147.659 1.00 118.21 ?  76  LYS S CE  1 
ATOM   7755 N NZ  . LYS E 5 76  ? 159.290 152.565 146.298 1.00 118.18 1  76  LYS S NZ  1 
ATOM   7756 N N   . ASN E 5 77  ? 155.620 150.985 151.386 1.00 108.79 ?  77  ASN S N   1 
ATOM   7757 C CA  . ASN E 5 77  ? 154.694 151.537 152.375 1.00 100.13 ?  77  ASN S CA  1 
ATOM   7758 C C   . ASN E 5 77  ? 154.980 153.012 152.660 1.00 101.20 ?  77  ASN S C   1 
ATOM   7759 O O   . ASN E 5 77  ? 155.352 153.399 153.767 1.00 103.13 ?  77  ASN S O   1 
ATOM   7760 C CB  . ASN E 5 77  ? 154.740 150.717 153.668 1.00 104.20 ?  77  ASN S CB  1 
ATOM   7761 C CG  . ASN E 5 77  ? 154.460 149.250 153.439 1.00 107.11 ?  77  ASN S CG  1 
ATOM   7762 O OD1 . ASN E 5 77  ? 153.780 148.875 152.487 1.00 109.47 ?  77  ASN S OD1 1 
ATOM   7763 N ND2 . ASN E 5 77  ? 154.992 148.408 154.313 1.00 99.05  ?  77  ASN S ND2 1 
ATOM   7764 N N   . THR E 5 78  ? 154.802 153.836 151.634 1.00 105.35 ?  78  THR S N   1 
ATOM   7765 C CA  . THR E 5 78  ? 154.964 155.276 151.767 1.00 100.88 ?  78  THR S CA  1 
ATOM   7766 C C   . THR E 5 78  ? 153.762 155.979 151.160 1.00 102.16 ?  78  THR S C   1 
ATOM   7767 O O   . THR E 5 78  ? 153.261 155.574 150.108 1.00 98.34  ?  78  THR S O   1 
ATOM   7768 C CB  . THR E 5 78  ? 156.250 155.766 151.094 1.00 104.51 ?  78  THR S CB  1 
ATOM   7769 O OG1 . THR E 5 78  ? 157.285 154.794 151.275 1.00 112.89 ?  78  THR S OG1 1 
ATOM   7770 C CG2 . THR E 5 78  ? 156.700 157.078 151.707 1.00 98.76  ?  78  THR S CG2 1 
ATOM   7771 N N   . LEU E 5 79  ? 153.300 157.028 151.834 1.00 97.48  ?  79  LEU S N   1 
ATOM   7772 C CA  . LEU E 5 79  ? 152.195 157.851 151.365 1.00 88.87  ?  79  LEU S CA  1 
ATOM   7773 C C   . LEU E 5 79  ? 152.708 159.260 151.115 1.00 88.57  ?  79  LEU S C   1 
ATOM   7774 O O   . LEU E 5 79  ? 153.412 159.825 151.957 1.00 84.59  ?  79  LEU S O   1 
ATOM   7775 C CB  . LEU E 5 79  ? 151.049 157.870 152.378 1.00 82.56  ?  79  LEU S CB  1 
ATOM   7776 C CG  . LEU E 5 79  ? 149.764 158.551 151.915 1.00 91.75  ?  79  LEU S CG  1 
ATOM   7777 C CD1 . LEU E 5 79  ? 148.947 157.613 151.057 1.00 92.10  ?  79  LEU S CD1 1 
ATOM   7778 C CD2 . LEU E 5 79  ? 148.956 159.021 153.099 1.00 84.51  ?  79  LEU S CD2 1 
ATOM   7779 N N   . PHE E 5 80  ? 152.356 159.820 149.963 1.00 87.17  ?  80  PHE S N   1 
ATOM   7780 C CA  . PHE E 5 80  ? 152.857 161.116 149.534 1.00 85.06  ?  80  PHE S CA  1 
ATOM   7781 C C   . PHE E 5 80  ? 151.717 162.112 149.401 1.00 94.05  ?  80  PHE S C   1 
ATOM   7782 O O   . PHE E 5 80  ? 150.578 161.745 149.103 1.00 94.84  ?  80  PHE S O   1 
ATOM   7783 C CB  . PHE E 5 80  ? 153.590 161.017 148.194 1.00 88.15  ?  80  PHE S CB  1 
ATOM   7784 C CG  . PHE E 5 80  ? 154.652 159.965 148.160 1.00 92.35  ?  80  PHE S CG  1 
ATOM   7785 C CD1 . PHE E 5 80  ? 155.844 160.147 148.832 1.00 89.92  ?  80  PHE S CD1 1 
ATOM   7786 C CD2 . PHE E 5 80  ? 154.460 158.795 147.454 1.00 91.38  ?  80  PHE S CD2 1 
ATOM   7787 C CE1 . PHE E 5 80  ? 156.821 159.184 148.802 1.00 87.31  ?  80  PHE S CE1 1 
ATOM   7788 C CE2 . PHE E 5 80  ? 155.433 157.828 147.422 1.00 93.48  ?  80  PHE S CE2 1 
ATOM   7789 C CZ  . PHE E 5 80  ? 156.616 158.023 148.096 1.00 91.42  ?  80  PHE S CZ  1 
ATOM   7790 N N   . LEU E 5 81  ? 152.040 163.383 149.622 1.00 89.59  ?  81  LEU S N   1 
ATOM   7791 C CA  . LEU E 5 81  ? 151.122 164.491 149.371 1.00 81.95  ?  81  LEU S CA  1 
ATOM   7792 C C   . LEU E 5 81  ? 151.898 165.548 148.594 1.00 90.98  ?  81  LEU S C   1 
ATOM   7793 O O   . LEU E 5 81  ? 152.650 166.329 149.181 1.00 94.02  ?  81  LEU S O   1 
ATOM   7794 C CB  . LEU E 5 81  ? 150.555 165.058 150.665 1.00 86.10  ?  81  LEU S CB  1 
ATOM   7795 C CG  . LEU E 5 81  ? 149.537 166.186 150.506 1.00 78.20  ?  81  LEU S CG  1 
ATOM   7796 C CD1 . LEU E 5 81  ? 148.252 165.666 149.895 1.00 79.90  ?  81  LEU S CD1 1 
ATOM   7797 C CD2 . LEU E 5 81  ? 149.265 166.840 151.841 1.00 82.69  ?  81  LEU S CD2 1 
ATOM   7798 N N   . GLN E 5 82  ? 151.727 165.559 147.276 1.00 102.47 ?  82  GLN S N   1 
ATOM   7799 C CA  . GLN E 5 82  ? 152.376 166.549 146.425 1.00 99.17  ?  82  GLN S CA  1 
ATOM   7800 C C   . GLN E 5 82  ? 151.519 167.804 146.410 1.00 102.09 ?  82  GLN S C   1 
ATOM   7801 O O   . GLN E 5 82  ? 150.401 167.791 145.888 1.00 106.20 ?  82  GLN S O   1 
ATOM   7802 C CB  . GLN E 5 82  ? 152.570 166.000 145.016 1.00 99.28  ?  82  GLN S CB  1 
ATOM   7803 C CG  . GLN E 5 82  ? 153.403 166.876 144.086 1.00 104.19 ?  82  GLN S CG  1 
ATOM   7804 C CD  . GLN E 5 82  ? 154.606 167.503 144.764 1.00 108.07 ?  82  GLN S CD  1 
ATOM   7805 O OE1 . GLN E 5 82  ? 154.510 168.569 145.371 1.00 107.20 ?  82  GLN S OE1 1 
ATOM   7806 N NE2 . GLN E 5 82  ? 155.753 166.850 144.646 1.00 104.05 ?  82  GLN S NE2 1 
ATOM   7807 N N   . MET E 5 83  ? 152.032 168.887 146.980 1.00 105.45 ?  83  MET S N   1 
ATOM   7808 C CA  . MET E 5 83  ? 151.309 170.146 147.041 1.00 107.92 ?  83  MET S CA  1 
ATOM   7809 C C   . MET E 5 83  ? 152.030 171.195 146.211 1.00 111.89 ?  83  MET S C   1 
ATOM   7810 O O   . MET E 5 83  ? 153.257 171.305 146.263 1.00 111.55 ?  83  MET S O   1 
ATOM   7811 C CB  . MET E 5 83  ? 151.158 170.642 148.477 1.00 110.03 ?  83  MET S CB  1 
ATOM   7812 C CG  . MET E 5 83  ? 151.289 169.575 149.538 1.00 112.43 ?  83  MET S CG  1 
ATOM   7813 S SD  . MET E 5 83  ? 150.990 170.269 151.168 1.00 120.17 ?  83  MET S SD  1 
ATOM   7814 C CE  . MET E 5 83  ? 152.655 170.422 151.771 1.00 103.31 ?  83  MET S CE  1 
ATOM   7815 N N   . THR E 5 84  ? 151.259 171.960 145.445 1.00 117.84 ?  84  THR S N   1 
ATOM   7816 C CA  . THR E 5 84  ? 151.785 173.020 144.601 1.00 113.40 ?  84  THR S CA  1 
ATOM   7817 C C   . THR E 5 84  ? 150.996 174.296 144.850 1.00 113.42 ?  84  THR S C   1 
ATOM   7818 O O   . THR E 5 84  ? 149.837 174.252 145.269 1.00 116.94 ?  84  THR S O   1 
ATOM   7819 C CB  . THR E 5 84  ? 151.714 172.650 143.115 1.00 111.53 ?  84  THR S CB  1 
ATOM   7820 O OG1 . THR E 5 84  ? 150.372 172.277 142.779 1.00 110.36 ?  84  THR S OG1 1 
ATOM   7821 C CG2 . THR E 5 84  ? 152.645 171.490 142.810 1.00 111.54 ?  84  THR S CG2 1 
ATOM   7822 N N   . SER E 5 85  ? 151.642 175.433 144.587 1.00 111.17 ?  85  SER S N   1 
ATOM   7823 C CA  . SER E 5 85  ? 151.039 176.752 144.784 1.00 112.66 ?  85  SER S CA  1 
ATOM   7824 C C   . SER E 5 85  ? 150.624 176.950 146.240 1.00 111.05 ?  85  SER S C   1 
ATOM   7825 O O   . SER E 5 85  ? 149.467 177.242 146.548 1.00 110.26 ?  85  SER S O   1 
ATOM   7826 C CB  . SER E 5 85  ? 149.853 176.964 143.840 1.00 110.92 ?  85  SER S CB  1 
ATOM   7827 O OG  . SER E 5 85  ? 150.229 176.750 142.492 1.00 111.94 ?  85  SER S OG  1 
ATOM   7828 N N   . LEU E 5 86  ? 151.587 176.786 147.142 1.00 109.21 ?  86  LEU S N   1 
ATOM   7829 C CA  . LEU E 5 86  ? 151.308 176.903 148.566 1.00 108.58 ?  86  LEU S CA  1 
ATOM   7830 C C   . LEU E 5 86  ? 150.991 178.346 148.931 1.00 110.40 ?  86  LEU S C   1 
ATOM   7831 O O   . LEU E 5 86  ? 151.724 179.267 148.563 1.00 119.18 ?  86  LEU S O   1 
ATOM   7832 C CB  . LEU E 5 86  ? 152.499 176.402 149.378 1.00 106.68 ?  86  LEU S CB  1 
ATOM   7833 C CG  . LEU E 5 86  ? 152.763 174.899 149.301 1.00 108.89 ?  86  LEU S CG  1 
ATOM   7834 C CD1 . LEU E 5 86  ? 153.814 174.491 150.310 1.00 110.38 ?  86  LEU S CD1 1 
ATOM   7835 C CD2 . LEU E 5 86  ? 151.481 174.128 149.527 1.00 109.86 ?  86  LEU S CD2 1 
ATOM   7836 N N   . ARG E 5 87  ? 149.898 178.541 149.658 1.00 106.86 ?  87  ARG S N   1 
ATOM   7837 C CA  . ARG E 5 87  ? 149.488 179.852 150.130 1.00 109.70 ?  87  ARG S CA  1 
ATOM   7838 C C   . ARG E 5 87  ? 149.607 179.905 151.646 1.00 113.04 ?  87  ARG S C   1 
ATOM   7839 O O   . ARG E 5 87  ? 149.877 178.901 152.307 1.00 117.59 ?  87  ARG S O   1 
ATOM   7840 C CB  . ARG E 5 87  ? 148.054 180.176 149.696 1.00 107.87 ?  87  ARG S CB  1 
ATOM   7841 C CG  . ARG E 5 87  ? 147.154 178.967 149.599 1.00 107.95 ?  87  ARG S CG  1 
ATOM   7842 C CD  . ARG E 5 87  ? 145.881 179.292 148.849 1.00 109.88 ?  87  ARG S CD  1 
ATOM   7843 N NE  . ARG E 5 87  ? 146.077 179.244 147.407 1.00 116.48 ?  87  ARG S NE  1 
ATOM   7844 C CZ  . ARG E 5 87  ? 145.159 178.837 146.542 1.00 117.84 ?  87  ARG S CZ  1 
ATOM   7845 N NH1 . ARG E 5 87  ? 143.962 178.439 146.940 1.00 111.50 1  87  ARG S NH1 1 
ATOM   7846 N NH2 . ARG E 5 87  ? 145.450 178.829 145.244 1.00 117.70 ?  87  ARG S NH2 1 
ATOM   7847 N N   . SER E 5 88  ? 149.400 181.102 152.198 1.00 117.45 ?  88  SER S N   1 
ATOM   7848 C CA  . SER E 5 88  ? 149.498 181.276 153.641 1.00 119.80 ?  88  SER S CA  1 
ATOM   7849 C C   . SER E 5 88  ? 148.424 180.504 154.393 1.00 116.21 ?  88  SER S C   1 
ATOM   7850 O O   . SER E 5 88  ? 148.590 180.243 155.588 1.00 111.56 ?  88  SER S O   1 
ATOM   7851 C CB  . SER E 5 88  ? 149.415 182.758 154.001 1.00 116.86 ?  88  SER S CB  1 
ATOM   7852 O OG  . SER E 5 88  ? 150.108 183.023 155.207 1.00 119.60 ?  88  SER S OG  1 
ATOM   7853 N N   . GLU E 5 89  ? 147.335 180.132 153.724 1.00 115.32 ?  89  GLU S N   1 
ATOM   7854 C CA  . GLU E 5 89  ? 146.269 179.372 154.358 1.00 112.81 ?  89  GLU S CA  1 
ATOM   7855 C C   . GLU E 5 89  ? 146.611 177.900 154.524 1.00 112.79 ?  89  GLU S C   1 
ATOM   7856 O O   . GLU E 5 89  ? 145.831 177.168 155.141 1.00 117.74 ?  89  GLU S O   1 
ATOM   7857 C CB  . GLU E 5 89  ? 144.978 179.507 153.550 1.00 116.21 ?  89  GLU S CB  1 
ATOM   7858 C CG  . GLU E 5 89  ? 144.559 180.943 153.277 1.00 118.78 ?  89  GLU S CG  1 
ATOM   7859 C CD  . GLU E 5 89  ? 144.408 181.762 154.545 1.00 124.02 ?  89  GLU S CD  1 
ATOM   7860 O OE1 . GLU E 5 89  ? 143.394 181.584 155.253 1.00 123.50 ?  89  GLU S OE1 1 
ATOM   7861 O OE2 . GLU E 5 89  ? 145.302 182.586 154.833 1.00 120.25 -1 89  GLU S OE2 1 
ATOM   7862 N N   . ASP E 5 90  ? 147.741 177.448 153.988 1.00 97.68  ?  90  ASP S N   1 
ATOM   7863 C CA  . ASP E 5 90  ? 148.148 176.055 154.084 1.00 98.29  ?  90  ASP S CA  1 
ATOM   7864 C C   . ASP E 5 90  ? 149.063 175.779 155.267 1.00 96.48  ?  90  ASP S C   1 
ATOM   7865 O O   . ASP E 5 90  ? 149.468 174.630 155.458 1.00 102.09 ?  90  ASP S O   1 
ATOM   7866 C CB  . ASP E 5 90  ? 148.842 175.619 152.794 1.00 97.74  ?  90  ASP S CB  1 
ATOM   7867 C CG  . ASP E 5 90  ? 147.880 175.475 151.642 1.00 104.74 ?  90  ASP S CG  1 
ATOM   7868 O OD1 . ASP E 5 90  ? 146.658 175.509 151.884 1.00 108.23 ?  90  ASP S OD1 1 
ATOM   7869 O OD2 . ASP E 5 90  ? 148.342 175.327 150.495 1.00 109.27 -1 90  ASP S OD2 1 
ATOM   7870 N N   . THR E 5 91  ? 149.400 176.793 156.059 1.00 87.04  ?  91  THR S N   1 
ATOM   7871 C CA  . THR E 5 91  ? 150.248 176.596 157.228 1.00 90.50  ?  91  THR S CA  1 
ATOM   7872 C C   . THR E 5 91  ? 149.499 175.753 158.249 1.00 95.30  ?  91  THR S C   1 
ATOM   7873 O O   . THR E 5 91  ? 148.499 176.201 158.817 1.00 101.97 ?  91  THR S O   1 
ATOM   7874 C CB  . THR E 5 91  ? 150.649 177.939 157.827 1.00 93.38  ?  91  THR S CB  1 
ATOM   7875 O OG1 . THR E 5 91  ? 151.410 178.681 156.868 1.00 102.84 ?  91  THR S OG1 1 
ATOM   7876 C CG2 . THR E 5 91  ? 151.486 177.733 159.075 1.00 91.57  ?  91  THR S CG2 1 
ATOM   7877 N N   . ALA E 5 92  ? 149.978 174.538 158.490 1.00 95.88  ?  92  ALA S N   1 
ATOM   7878 C CA  . ALA E 5 92  ? 149.279 173.607 159.363 1.00 95.41  ?  92  ALA S CA  1 
ATOM   7879 C C   . ALA E 5 92  ? 150.224 172.477 159.747 1.00 98.30  ?  92  ALA S C   1 
ATOM   7880 O O   . ALA E 5 92  ? 151.391 172.450 159.350 1.00 100.04 ?  92  ALA S O   1 
ATOM   7881 C CB  . ALA E 5 92  ? 148.020 173.062 158.686 1.00 87.61  ?  92  ALA S CB  1 
ATOM   7882 N N   . MET E 5 93  ? 149.703 171.546 160.540 1.00 97.78  ?  93  MET S N   1 
ATOM   7883 C CA  . MET E 5 93  ? 150.362 170.285 160.845 1.00 90.95  ?  93  MET S CA  1 
ATOM   7884 C C   . MET E 5 93  ? 149.564 169.164 160.198 1.00 91.53  ?  93  MET S C   1 
ATOM   7885 O O   . MET E 5 93  ? 148.360 169.043 160.434 1.00 96.55  ?  93  MET S O   1 
ATOM   7886 C CB  . MET E 5 93  ? 150.462 170.067 162.355 1.00 86.96  ?  93  MET S CB  1 
ATOM   7887 C CG  . MET E 5 93  ? 150.811 168.648 162.754 1.00 90.46  ?  93  MET S CG  1 
ATOM   7888 S SD  . MET E 5 93  ? 152.448 168.512 163.488 1.00 110.12 ?  93  MET S SD  1 
ATOM   7889 C CE  . MET E 5 93  ? 152.195 169.371 165.035 1.00 93.19  ?  93  MET S CE  1 
ATOM   7890 N N   . TYR E 5 94  ? 150.230 168.349 159.390 1.00 77.99  ?  94  TYR S N   1 
ATOM   7891 C CA  . TYR E 5 94  ? 149.560 167.364 158.553 1.00 79.46  ?  94  TYR S CA  1 
ATOM   7892 C C   . TYR E 5 94  ? 149.691 165.977 159.164 1.00 82.75  ?  94  TYR S C   1 
ATOM   7893 O O   . TYR E 5 94  ? 150.787 165.568 159.557 1.00 88.75  ?  94  TYR S O   1 
ATOM   7894 C CB  . TYR E 5 94  ? 150.139 167.379 157.138 1.00 76.77  ?  94  TYR S CB  1 
ATOM   7895 C CG  . TYR E 5 94  ? 149.795 168.623 156.354 1.00 78.99  ?  94  TYR S CG  1 
ATOM   7896 C CD1 . TYR E 5 94  ? 150.374 169.843 156.663 1.00 79.91  ?  94  TYR S CD1 1 
ATOM   7897 C CD2 . TYR E 5 94  ? 148.889 168.577 155.307 1.00 82.04  ?  94  TYR S CD2 1 
ATOM   7898 C CE1 . TYR E 5 94  ? 150.061 170.978 155.957 1.00 76.45  ?  94  TYR S CE1 1 
ATOM   7899 C CE2 . TYR E 5 94  ? 148.570 169.708 154.595 1.00 83.00  ?  94  TYR S CE2 1 
ATOM   7900 C CZ  . TYR E 5 94  ? 149.159 170.905 154.924 1.00 81.34  ?  94  TYR S CZ  1 
ATOM   7901 O OH  . TYR E 5 94  ? 148.844 172.037 154.216 1.00 81.17  ?  94  TYR S OH  1 
ATOM   7902 N N   . TYR E 5 95  ? 148.576 165.258 159.231 1.00 79.25  ?  95  TYR S N   1 
ATOM   7903 C CA  . TYR E 5 95  ? 148.518 163.918 159.790 1.00 72.61  ?  95  TYR S CA  1 
ATOM   7904 C C   . TYR E 5 95  ? 148.219 162.904 158.696 1.00 81.47  ?  95  TYR S C   1 
ATOM   7905 O O   . TYR E 5 95  ? 147.666 163.234 157.647 1.00 91.65  ?  95  TYR S O   1 
ATOM   7906 C CB  . TYR E 5 95  ? 147.455 163.827 160.887 1.00 75.50  ?  95  TYR S CB  1 
ATOM   7907 C CG  . TYR E 5 95  ? 147.711 164.741 162.058 1.00 73.72  ?  95  TYR S CG  1 
ATOM   7908 C CD1 . TYR E 5 95  ? 148.705 164.457 162.976 1.00 77.36  ?  95  TYR S CD1 1 
ATOM   7909 C CD2 . TYR E 5 95  ? 146.958 165.887 162.245 1.00 74.40  ?  95  TYR S CD2 1 
ATOM   7910 C CE1 . TYR E 5 95  ? 148.943 165.286 164.044 1.00 81.65  ?  95  TYR S CE1 1 
ATOM   7911 C CE2 . TYR E 5 95  ? 147.189 166.722 163.312 1.00 82.71  ?  95  TYR S CE2 1 
ATOM   7912 C CZ  . TYR E 5 95  ? 148.183 166.416 164.208 1.00 86.97  ?  95  TYR S CZ  1 
ATOM   7913 O OH  . TYR E 5 95  ? 148.421 167.245 165.276 1.00 84.41  ?  95  TYR S OH  1 
ATOM   7914 N N   . CYS E 5 96  ? 148.570 161.650 158.970 1.00 79.94  ?  96  CYS S N   1 
ATOM   7915 C CA  . CYS E 5 96  ? 148.522 160.583 157.979 1.00 77.98  ?  96  CYS S CA  1 
ATOM   7916 C C   . CYS E 5 96  ? 147.579 159.473 158.415 1.00 87.93  ?  96  CYS S C   1 
ATOM   7917 O O   . CYS E 5 96  ? 147.962 158.301 158.432 1.00 108.16 ?  96  CYS S O   1 
ATOM   7918 C CB  . CYS E 5 96  ? 149.923 160.028 157.742 1.00 83.52  ?  96  CYS S CB  1 
ATOM   7919 S SG  . CYS E 5 96  ? 150.138 158.883 156.375 1.00 121.48 ?  96  CYS S SG  1 
ATOM   7920 N N   . VAL E 5 97  ? 146.359 159.839 158.806 1.00 61.18  ?  97  VAL S N   1 
ATOM   7921 C CA  . VAL E 5 97  ? 145.413 158.872 159.343 1.00 59.54  ?  97  VAL S CA  1 
ATOM   7922 C C   . VAL E 5 97  ? 145.244 157.689 158.403 1.00 59.30  ?  97  VAL S C   1 
ATOM   7923 O O   . VAL E 5 97  ? 145.167 157.844 157.181 1.00 73.02  ?  97  VAL S O   1 
ATOM   7924 C CB  . VAL E 5 97  ? 144.063 159.558 159.600 1.00 57.73  ?  97  VAL S CB  1 
ATOM   7925 C CG1 . VAL E 5 97  ? 143.269 158.767 160.603 1.00 64.93  ?  97  VAL S CG1 1 
ATOM   7926 C CG2 . VAL E 5 97  ? 144.284 160.976 160.069 1.00 67.26  ?  97  VAL S CG2 1 
ATOM   7927 N N   . ARG E 5 98  ? 145.189 156.496 158.982 1.00 67.71  ?  98  ARG S N   1 
ATOM   7928 C CA  . ARG E 5 98  ? 144.857 155.276 158.265 1.00 65.86  ?  98  ARG S CA  1 
ATOM   7929 C C   . ARG E 5 98  ? 143.426 154.874 158.588 1.00 70.91  ?  98  ARG S C   1 
ATOM   7930 O O   . ARG E 5 98  ? 142.942 155.086 159.700 1.00 80.19  ?  98  ARG S O   1 
ATOM   7931 C CB  . ARG E 5 98  ? 145.813 154.141 158.633 1.00 69.60  ?  98  ARG S CB  1 
ATOM   7932 C CG  . ARG E 5 98  ? 145.739 153.712 160.085 1.00 66.38  ?  98  ARG S CG  1 
ATOM   7933 C CD  . ARG E 5 98  ? 146.266 152.306 160.286 1.00 70.69  ?  98  ARG S CD  1 
ATOM   7934 N NE  . ARG E 5 98  ? 145.593 151.629 161.386 1.00 72.08  ?  98  ARG S NE  1 
ATOM   7935 C CZ  . ARG E 5 98  ? 145.940 150.443 161.866 1.00 68.82  ?  98  ARG S CZ  1 
ATOM   7936 N NH1 . ARG E 5 98  ? 146.959 149.766 161.366 1.00 73.93  1  98  ARG S NH1 1 
ATOM   7937 N NH2 . ARG E 5 98  ? 145.250 149.924 162.875 1.00 72.75  ?  98  ARG S NH2 1 
ATOM   7938 N N   . SER E 5 99  ? 142.743 154.302 157.602 1.00 61.29  ?  99  SER S N   1 
ATOM   7939 C CA  . SER E 5 99  ? 141.355 153.904 157.794 1.00 63.25  ?  99  SER S CA  1 
ATOM   7940 C C   . SER E 5 99  ? 141.034 152.745 156.870 1.00 61.44  ?  99  SER S C   1 
ATOM   7941 O O   . SER E 5 99  ? 141.199 152.858 155.653 1.00 71.71  ?  99  SER S O   1 
ATOM   7942 C CB  . SER E 5 99  ? 140.410 155.074 157.535 1.00 63.03  ?  99  SER S CB  1 
ATOM   7943 O OG  . SER E 5 99  ? 140.367 155.392 156.160 1.00 74.97  ?  99  SER S OG  1 
ATOM   7944 N N   . ILE E 5 100 ? 140.570 151.642 157.445 1.00 63.12  ?  100 ILE S N   1 
ATOM   7945 C CA  . ILE E 5 100 ? 140.185 150.453 156.699 1.00 61.21  ?  100 ILE S CA  1 
ATOM   7946 C C   . ILE E 5 100 ? 138.668 150.339 156.745 1.00 62.14  ?  100 ILE S C   1 
ATOM   7947 O O   . ILE E 5 100 ? 138.042 150.676 157.755 1.00 63.16  ?  100 ILE S O   1 
ATOM   7948 C CB  . ILE E 5 100 ? 140.877 149.193 157.260 1.00 66.40  ?  100 ILE S CB  1 
ATOM   7949 C CG1 . ILE E 5 100 ? 140.805 148.041 156.264 1.00 65.92  ?  100 ILE S CG1 1 
ATOM   7950 C CG2 . ILE E 5 100 ? 140.293 148.790 158.601 1.00 72.91  ?  100 ILE S CG2 1 
ATOM   7951 C CD1 . ILE E 5 100 ? 141.732 146.910 156.602 1.00 59.57  ?  100 ILE S CD1 1 
ATOM   7952 N N   . TYR E 5 101 ? 138.073 149.903 155.638 1.00 61.02  ?  101 TYR S N   1 
ATOM   7953 C CA  . TYR E 5 101 ? 136.623 149.939 155.475 1.00 57.74  ?  101 TYR S CA  1 
ATOM   7954 C C   . TYR E 5 101 ? 136.098 148.556 155.127 1.00 64.82  ?  101 TYR S C   1 
ATOM   7955 O O   . TYR E 5 101 ? 136.279 148.083 154.002 1.00 73.36  ?  101 TYR S O   1 
ATOM   7956 C CB  . TYR E 5 101 ? 136.219 150.943 154.399 1.00 63.12  ?  101 TYR S CB  1 
ATOM   7957 C CG  . TYR E 5 101 ? 136.594 152.368 154.714 1.00 65.37  ?  101 TYR S CG  1 
ATOM   7958 C CD1 . TYR E 5 101 ? 135.836 153.126 155.587 1.00 66.58  ?  101 TYR S CD1 1 
ATOM   7959 C CD2 . TYR E 5 101 ? 137.705 152.953 154.136 1.00 61.98  ?  101 TYR S CD2 1 
ATOM   7960 C CE1 . TYR E 5 101 ? 136.177 154.420 155.875 1.00 62.49  ?  101 TYR S CE1 1 
ATOM   7961 C CE2 . TYR E 5 101 ? 138.051 154.248 154.419 1.00 53.26  ?  101 TYR S CE2 1 
ATOM   7962 C CZ  . TYR E 5 101 ? 137.284 154.976 155.289 1.00 60.04  ?  101 TYR S CZ  1 
ATOM   7963 O OH  . TYR E 5 101 ? 137.627 156.272 155.576 1.00 82.75  ?  101 TYR S OH  1 
ATOM   7964 N N   . TYR E 5 102 ? 135.446 147.918 156.091 1.00 64.39  ?  102 TYR S N   1 
ATOM   7965 C CA  . TYR E 5 102 ? 134.621 146.744 155.856 1.00 56.93  ?  102 TYR S CA  1 
ATOM   7966 C C   . TYR E 5 102 ? 133.529 146.753 156.913 1.00 67.43  ?  102 TYR S C   1 
ATOM   7967 O O   . TYR E 5 102 ? 133.451 147.669 157.734 1.00 76.13  ?  102 TYR S O   1 
ATOM   7968 C CB  . TYR E 5 102 ? 135.440 145.450 155.878 1.00 52.87  ?  102 TYR S CB  1 
ATOM   7969 C CG  . TYR E 5 102 ? 136.394 145.310 157.040 1.00 58.52  ?  102 TYR S CG  1 
ATOM   7970 C CD1 . TYR E 5 102 ? 135.978 144.769 158.245 1.00 56.55  ?  102 TYR S CD1 1 
ATOM   7971 C CD2 . TYR E 5 102 ? 137.713 145.704 156.926 1.00 62.26  ?  102 TYR S CD2 1 
ATOM   7972 C CE1 . TYR E 5 102 ? 136.844 144.636 159.300 1.00 54.58  ?  102 TYR S CE1 1 
ATOM   7973 C CE2 . TYR E 5 102 ? 138.583 145.575 157.975 1.00 69.75  ?  102 TYR S CE2 1 
ATOM   7974 C CZ  . TYR E 5 102 ? 138.145 145.042 159.159 1.00 69.95  ?  102 TYR S CZ  1 
ATOM   7975 O OH  . TYR E 5 102 ? 139.021 144.912 160.209 1.00 75.25  ?  102 TYR S OH  1 
ATOM   7976 N N   . TYR E 5 103 ? 132.674 145.738 156.889 1.00 70.46  ?  103 TYR S N   1 
ATOM   7977 C CA  . TYR E 5 103 ? 131.597 145.682 157.865 1.00 60.34  ?  103 TYR S CA  1 
ATOM   7978 C C   . TYR E 5 103 ? 132.164 145.509 159.266 1.00 71.46  ?  103 TYR S C   1 
ATOM   7979 O O   . TYR E 5 103 ? 132.874 144.539 159.543 1.00 79.10  ?  103 TYR S O   1 
ATOM   7980 C CB  . TYR E 5 103 ? 130.634 144.545 157.541 1.00 55.77  ?  103 TYR S CB  1 
ATOM   7981 C CG  . TYR E 5 103 ? 129.543 144.420 158.570 1.00 67.07  ?  103 TYR S CG  1 
ATOM   7982 C CD1 . TYR E 5 103 ? 128.504 145.331 158.615 1.00 68.75  ?  103 TYR S CD1 1 
ATOM   7983 C CD2 . TYR E 5 103 ? 129.568 143.411 159.517 1.00 72.76  ?  103 TYR S CD2 1 
ATOM   7984 C CE1 . TYR E 5 103 ? 127.513 145.231 159.560 1.00 70.39  ?  103 TYR S CE1 1 
ATOM   7985 C CE2 . TYR E 5 103 ? 128.584 143.306 160.466 1.00 69.84  ?  103 TYR S CE2 1 
ATOM   7986 C CZ  . TYR E 5 103 ? 127.558 144.217 160.484 1.00 76.89  ?  103 TYR S CZ  1 
ATOM   7987 O OH  . TYR E 5 103 ? 126.570 144.112 161.431 1.00 90.77  ?  103 TYR S OH  1 
ATOM   7988 N N   . GLY E 5 104 ? 131.840 146.444 160.153 1.00 65.31  ?  104 GLY S N   1 
ATOM   7989 C CA  . GLY E 5 104 ? 132.303 146.390 161.520 1.00 60.62  ?  104 GLY S CA  1 
ATOM   7990 C C   . GLY E 5 104 ? 133.678 146.965 161.761 1.00 67.57  ?  104 GLY S C   1 
ATOM   7991 O O   . GLY E 5 104 ? 134.166 146.902 162.895 1.00 77.78  ?  104 GLY S O   1 
ATOM   7992 N N   . SER E 5 105 ? 134.320 147.525 160.741 1.00 65.30  ?  105 SER S N   1 
ATOM   7993 C CA  . SER E 5 105 ? 135.649 148.083 160.905 1.00 65.86  ?  105 SER S CA  1 
ATOM   7994 C C   . SER E 5 105 ? 135.583 149.409 161.656 1.00 80.12  ?  105 SER S C   1 
ATOM   7995 O O   . SER E 5 105 ? 134.518 149.997 161.850 1.00 93.36  ?  105 SER S O   1 
ATOM   7996 C CB  . SER E 5 105 ? 136.316 148.279 159.549 1.00 76.02  ?  105 SER S CB  1 
ATOM   7997 O OG  . SER E 5 105 ? 135.474 149.008 158.677 1.00 82.82  ?  105 SER S OG  1 
ATOM   7998 N N   . SER E 5 106 ? 136.753 149.881 162.083 1.00 75.22  ?  106 SER S N   1 
ATOM   7999 C CA  . SER E 5 106 ? 136.891 151.153 162.787 1.00 66.75  ?  106 SER S CA  1 
ATOM   8000 C C   . SER E 5 106 ? 137.831 152.044 161.990 1.00 71.82  ?  106 SER S C   1 
ATOM   8001 O O   . SER E 5 106 ? 139.058 151.979 162.161 1.00 80.15  ?  106 SER S O   1 
ATOM   8002 C CB  . SER E 5 106 ? 137.406 150.943 164.208 1.00 74.65  ?  106 SER S CB  1 
ATOM   8003 O OG  . SER E 5 106 ? 138.728 150.445 164.199 1.00 80.76  ?  106 SER S OG  1 
ATOM   8004 N N   . PRO E 5 107 ? 137.306 152.880 161.101 1.00 75.50  ?  107 PRO S N   1 
ATOM   8005 C CA  . PRO E 5 107 ? 138.164 153.800 160.354 1.00 70.47  ?  107 PRO S CA  1 
ATOM   8006 C C   . PRO E 5 107 ? 138.745 154.877 161.255 1.00 75.83  ?  107 PRO S C   1 
ATOM   8007 O O   . PRO E 5 107 ? 138.238 155.160 162.341 1.00 90.98  ?  107 PRO S O   1 
ATOM   8008 C CB  . PRO E 5 107 ? 137.218 154.404 159.312 1.00 59.65  ?  107 PRO S CB  1 
ATOM   8009 C CG  . PRO E 5 107 ? 136.064 153.481 159.255 1.00 73.07  ?  107 PRO S CG  1 
ATOM   8010 C CD  . PRO E 5 107 ? 135.918 152.916 160.622 1.00 79.69  ?  107 PRO S CD  1 
ATOM   8011 N N   . PHE E 5 108 ? 139.840 155.470 160.781 1.00 61.83  ?  108 PHE S N   1 
ATOM   8012 C CA  . PHE E 5 108 ? 140.519 156.570 161.466 1.00 56.09  ?  108 PHE S CA  1 
ATOM   8013 C C   . PHE E 5 108 ? 141.062 156.152 162.826 1.00 65.64  ?  108 PHE S C   1 
ATOM   8014 O O   . PHE E 5 108 ? 141.144 156.967 163.744 1.00 77.51  ?  108 PHE S O   1 
ATOM   8015 C CB  . PHE E 5 108 ? 139.600 157.786 161.616 1.00 56.93  ?  108 PHE S CB  1 
ATOM   8016 C CG  . PHE E 5 108 ? 139.416 158.563 160.349 1.00 69.98  ?  108 PHE S CG  1 
ATOM   8017 C CD1 . PHE E 5 108 ? 138.632 158.068 159.328 1.00 67.56  ?  108 PHE S CD1 1 
ATOM   8018 C CD2 . PHE E 5 108 ? 140.028 159.789 160.180 1.00 69.87  ?  108 PHE S CD2 1 
ATOM   8019 C CE1 . PHE E 5 108 ? 138.467 158.776 158.168 1.00 67.61  ?  108 PHE S CE1 1 
ATOM   8020 C CE2 . PHE E 5 108 ? 139.867 160.500 159.018 1.00 68.14  ?  108 PHE S CE2 1 
ATOM   8021 C CZ  . PHE E 5 108 ? 139.086 159.993 158.011 1.00 72.80  ?  108 PHE S CZ  1 
ATOM   8022 N N   . ASP E 5 109 ? 141.450 154.884 162.967 1.00 77.23  ?  109 ASP S N   1 
ATOM   8023 C CA  . ASP E 5 109 ? 141.865 154.388 164.274 1.00 69.48  ?  109 ASP S CA  1 
ATOM   8024 C C   . ASP E 5 109 ? 143.265 154.843 164.660 1.00 75.82  ?  109 ASP S C   1 
ATOM   8025 O O   . ASP E 5 109 ? 143.522 155.080 165.845 1.00 81.32  ?  109 ASP S O   1 
ATOM   8026 C CB  . ASP E 5 109 ? 141.774 152.863 164.319 1.00 62.39  ?  109 ASP S CB  1 
ATOM   8027 C CG  . ASP E 5 109 ? 142.230 152.213 163.038 1.00 83.86  ?  109 ASP S CG  1 
ATOM   8028 O OD1 . ASP E 5 109 ? 141.930 152.751 161.955 1.00 89.23  ?  109 ASP S OD1 1 
ATOM   8029 O OD2 . ASP E 5 109 ? 142.886 151.154 163.111 1.00 90.39  -1 109 ASP S OD2 1 
ATOM   8030 N N   . PHE E 5 110 ? 144.179 154.976 163.705 1.00 77.09  ?  110 PHE S N   1 
ATOM   8031 C CA  . PHE E 5 110 ? 145.547 155.377 164.003 1.00 75.75  ?  110 PHE S CA  1 
ATOM   8032 C C   . PHE E 5 110 ? 145.899 156.655 163.258 1.00 70.54  ?  110 PHE S C   1 
ATOM   8033 O O   . PHE E 5 110 ? 145.612 156.783 162.066 1.00 83.21  ?  110 PHE S O   1 
ATOM   8034 C CB  . PHE E 5 110 ? 146.547 154.275 163.652 1.00 81.18  ?  110 PHE S CB  1 
ATOM   8035 C CG  . PHE E 5 110 ? 147.894 154.479 164.270 1.00 82.15  ?  110 PHE S CG  1 
ATOM   8036 C CD1 . PHE E 5 110 ? 148.075 154.311 165.627 1.00 78.89  ?  110 PHE S CD1 1 
ATOM   8037 C CD2 . PHE E 5 110 ? 148.970 154.872 163.503 1.00 83.50  ?  110 PHE S CD2 1 
ATOM   8038 C CE1 . PHE E 5 110 ? 149.306 154.513 166.201 1.00 84.81  ?  110 PHE S CE1 1 
ATOM   8039 C CE2 . PHE E 5 110 ? 150.202 155.078 164.073 1.00 84.30  ?  110 PHE S CE2 1 
ATOM   8040 C CZ  . PHE E 5 110 ? 150.370 154.898 165.423 1.00 87.46  ?  110 PHE S CZ  1 
ATOM   8041 N N   . TRP E 5 111 ? 146.531 157.587 163.964 1.00 65.20  ?  111 TRP S N   1 
ATOM   8042 C CA  . TRP E 5 111 ? 146.962 158.861 163.411 1.00 63.92  ?  111 TRP S CA  1 
ATOM   8043 C C   . TRP E 5 111 ? 148.475 158.971 163.512 1.00 69.62  ?  111 TRP S C   1 
ATOM   8044 O O   . TRP E 5 111 ? 149.071 158.545 164.503 1.00 87.59  ?  111 TRP S O   1 
ATOM   8045 C CB  . TRP E 5 111 ? 146.317 160.036 164.148 1.00 66.76  ?  111 TRP S CB  1 
ATOM   8046 C CG  . TRP E 5 111 ? 144.854 160.190 163.901 1.00 74.55  ?  111 TRP S CG  1 
ATOM   8047 C CD1 . TRP E 5 111 ? 143.895 159.237 164.047 1.00 74.28  ?  111 TRP S CD1 1 
ATOM   8048 C CD2 . TRP E 5 111 ? 144.179 161.374 163.473 1.00 64.08  ?  111 TRP S CD2 1 
ATOM   8049 N NE1 . TRP E 5 111 ? 142.666 159.749 163.732 1.00 73.98  ?  111 TRP S NE1 1 
ATOM   8050 C CE2 . TRP E 5 111 ? 142.813 161.063 163.376 1.00 73.42  ?  111 TRP S CE2 1 
ATOM   8051 C CE3 . TRP E 5 111 ? 144.598 162.668 163.158 1.00 64.72  ?  111 TRP S CE3 1 
ATOM   8052 C CZ2 . TRP E 5 111 ? 141.863 161.995 162.978 1.00 63.76  ?  111 TRP S CZ2 1 
ATOM   8053 C CZ3 . TRP E 5 111 ? 143.655 163.590 162.765 1.00 70.48  ?  111 TRP S CZ3 1 
ATOM   8054 C CH2 . TRP E 5 111 ? 142.303 163.251 162.679 1.00 64.35  ?  111 TRP S CH2 1 
ATOM   8055 N N   . GLY E 5 112 ? 149.092 159.549 162.494 1.00 78.03  ?  112 GLY S N   1 
ATOM   8056 C CA  . GLY E 5 112 ? 150.522 159.756 162.519 1.00 83.54  ?  112 GLY S CA  1 
ATOM   8057 C C   . GLY E 5 112 ? 150.924 160.837 163.501 1.00 79.70  ?  112 GLY S C   1 
ATOM   8058 O O   . GLY E 5 112 ? 150.101 161.548 164.072 1.00 84.67  ?  112 GLY S O   1 
ATOM   8059 N N   . GLN E 5 113 ? 152.236 160.954 163.709 1.00 90.23  ?  113 GLN S N   1 
ATOM   8060 C CA  . GLN E 5 113 ? 152.739 161.949 164.650 1.00 97.80  ?  113 GLN S CA  1 
ATOM   8061 C C   . GLN E 5 113 ? 152.554 163.367 164.128 1.00 99.21  ?  113 GLN S C   1 
ATOM   8062 O O   . GLN E 5 113 ? 152.313 164.288 164.916 1.00 93.02  ?  113 GLN S O   1 
ATOM   8063 C CB  . GLN E 5 113 ? 154.209 161.685 164.963 1.00 98.46  ?  113 GLN S CB  1 
ATOM   8064 C CG  . GLN E 5 113 ? 154.435 161.066 166.331 1.00 101.87 ?  113 GLN S CG  1 
ATOM   8065 C CD  . GLN E 5 113 ? 153.507 161.635 167.387 1.00 106.00 ?  113 GLN S CD  1 
ATOM   8066 O OE1 . GLN E 5 113 ? 153.532 162.831 167.674 1.00 103.25 ?  113 GLN S OE1 1 
ATOM   8067 N NE2 . GLN E 5 113 ? 152.675 160.778 167.967 1.00 99.92  ?  113 GLN S NE2 1 
ATOM   8068 N N   . GLY E 5 114 ? 152.669 163.566 162.820 1.00 101.50 ?  114 GLY S N   1 
ATOM   8069 C CA  . GLY E 5 114 ? 152.447 164.872 162.235 1.00 97.96  ?  114 GLY S CA  1 
ATOM   8070 C C   . GLY E 5 114 ? 153.719 165.632 161.936 1.00 100.80 ?  114 GLY S C   1 
ATOM   8071 O O   . GLY E 5 114 ? 154.666 165.608 162.726 1.00 105.73 ?  114 GLY S O   1 
ATOM   8072 N N   . THR E 5 115 ? 153.748 166.314 160.796 1.00 102.61 ?  115 THR S N   1 
ATOM   8073 C CA  . THR E 5 115 ? 154.858 167.176 160.422 1.00 99.58  ?  115 THR S CA  1 
ATOM   8074 C C   . THR E 5 115 ? 154.327 168.575 160.152 1.00 99.31  ?  115 THR S C   1 
ATOM   8075 O O   . THR E 5 115 ? 153.245 168.740 159.583 1.00 101.37 ?  115 THR S O   1 
ATOM   8076 C CB  . THR E 5 115 ? 155.613 166.629 159.200 1.00 104.73 ?  115 THR S CB  1 
ATOM   8077 O OG1 . THR E 5 115 ? 156.786 167.417 158.968 1.00 110.75 ?  115 THR S OG1 1 
ATOM   8078 C CG2 . THR E 5 115 ? 154.738 166.633 157.958 1.00 100.26 ?  115 THR S CG2 1 
ATOM   8079 N N   . THR E 5 116 ? 155.081 169.579 160.583 1.00 101.77 ?  116 THR S N   1 
ATOM   8080 C CA  . THR E 5 116 ? 154.637 170.964 160.540 1.00 104.69 ?  116 THR S CA  1 
ATOM   8081 C C   . THR E 5 116 ? 155.209 171.653 159.311 1.00 104.64 ?  116 THR S C   1 
ATOM   8082 O O   . THR E 5 116 ? 156.426 171.659 159.107 1.00 107.83 ?  116 THR S O   1 
ATOM   8083 C CB  . THR E 5 116 ? 155.064 171.712 161.803 1.00 107.42 ?  116 THR S CB  1 
ATOM   8084 O OG1 . THR E 5 116 ? 154.276 171.268 162.913 1.00 110.62 ?  116 THR S OG1 1 
ATOM   8085 C CG2 . THR E 5 116 ? 154.872 173.207 161.626 1.00 102.33 ?  116 THR S CG2 1 
ATOM   8086 N N   . LEU E 5 117 ? 154.329 172.229 158.497 1.00 103.06 ?  117 LEU S N   1 
ATOM   8087 C CA  . LEU E 5 117 ? 154.721 172.985 157.318 1.00 99.57  ?  117 LEU S CA  1 
ATOM   8088 C C   . LEU E 5 117 ? 154.253 174.424 157.469 1.00 99.64  ?  117 LEU S C   1 
ATOM   8089 O O   . LEU E 5 117 ? 153.069 174.674 157.711 1.00 100.63 ?  117 LEU S O   1 
ATOM   8090 C CB  . LEU E 5 117 ? 154.142 172.365 156.046 1.00 93.88  ?  117 LEU S CB  1 
ATOM   8091 C CG  . LEU E 5 117 ? 154.016 173.303 154.849 1.00 95.21  ?  117 LEU S CG  1 
ATOM   8092 C CD1 . LEU E 5 117 ? 154.649 172.676 153.632 1.00 102.27 ?  117 LEU S CD1 1 
ATOM   8093 C CD2 . LEU E 5 117 ? 152.561 173.613 154.578 1.00 97.41  ?  117 LEU S CD2 1 
ATOM   8094 N N   . THR E 5 118 ? 155.183 175.363 157.320 1.00 113.64 ?  118 THR S N   1 
ATOM   8095 C CA  . THR E 5 118 ? 154.908 176.784 157.475 1.00 112.33 ?  118 THR S CA  1 
ATOM   8096 C C   . THR E 5 118 ? 155.098 177.481 156.138 1.00 112.18 ?  118 THR S C   1 
ATOM   8097 O O   . THR E 5 118 ? 156.122 177.291 155.475 1.00 117.00 ?  118 THR S O   1 
ATOM   8098 C CB  . THR E 5 118 ? 155.825 177.414 158.524 1.00 111.54 ?  118 THR S CB  1 
ATOM   8099 O OG1 . THR E 5 118 ? 156.024 176.492 159.602 1.00 116.41 ?  118 THR S OG1 1 
ATOM   8100 C CG2 . THR E 5 118 ? 155.214 178.691 159.063 1.00 110.83 ?  118 THR S CG2 1 
ATOM   8101 N N   . VAL E 5 119 ? 154.114 178.283 155.747 1.00 109.75 ?  119 VAL S N   1 
ATOM   8102 C CA  . VAL E 5 119 ? 154.175 179.074 154.524 1.00 108.37 ?  119 VAL S CA  1 
ATOM   8103 C C   . VAL E 5 119 ? 154.301 180.534 154.929 1.00 111.65 ?  119 VAL S C   1 
ATOM   8104 O O   . VAL E 5 119 ? 153.445 181.062 155.650 1.00 111.74 ?  119 VAL S O   1 
ATOM   8105 C CB  . VAL E 5 119 ? 152.944 178.846 153.638 1.00 107.26 ?  119 VAL S CB  1 
ATOM   8106 C CG1 . VAL E 5 119 ? 153.047 179.677 152.378 1.00 109.92 ?  119 VAL S CG1 1 
ATOM   8107 C CG2 . VAL E 5 119 ? 152.806 177.375 153.297 1.00 103.46 ?  119 VAL S CG2 1 
ATOM   8108 N N   . SER E 5 120 ? 155.363 181.187 154.465 1.00 127.14 ?  120 SER S N   1 
ATOM   8109 C CA  . SER E 5 120 ? 155.646 182.557 154.862 1.00 128.56 ?  120 SER S CA  1 
ATOM   8110 C C   . SER E 5 120 ? 154.635 183.516 154.235 1.00 133.24 ?  120 SER S C   1 
ATOM   8111 O O   . SER E 5 120 ? 153.732 183.124 153.491 1.00 130.93 ?  120 SER S O   1 
ATOM   8112 C CB  . SER E 5 120 ? 157.071 182.936 154.470 1.00 126.08 ?  120 SER S CB  1 
ATOM   8113 O OG  . SER E 5 120 ? 157.335 184.294 154.771 1.00 128.42 ?  120 SER S OG  1 
ATOM   8114 N N   . SER E 5 121 ? 154.792 184.799 154.546 1.00 137.13 ?  121 SER S N   1 
ATOM   8115 C CA  . SER E 5 121 ? 153.905 185.828 154.018 1.00 136.47 ?  121 SER S CA  1 
ATOM   8116 C C   . SER E 5 121 ? 154.673 186.825 153.156 1.00 136.60 ?  121 SER S C   1 
ATOM   8117 O O   . SER E 5 121 ? 154.671 186.730 151.929 1.00 133.76 ?  121 SER S O   1 
ATOM   8118 C CB  . SER E 5 121 ? 153.192 186.558 155.157 1.00 133.06 ?  121 SER S CB  1 
ATOM   8119 O OG  . SER E 5 121 ? 152.404 187.626 154.662 1.00 135.03 ?  121 SER S OG  1 
ATOM   8120 N N   . SER E 5 137 ? 127.645 173.189 150.394 1.00 110.94 ?  124 SER S N   1 
ATOM   8121 C CA  . SER E 5 137 ? 126.810 171.994 150.439 1.00 121.27 ?  124 SER S CA  1 
ATOM   8122 C C   . SER E 5 137 ? 127.353 170.980 151.439 1.00 122.49 ?  124 SER S C   1 
ATOM   8123 O O   . SER E 5 137 ? 126.738 169.943 151.681 1.00 119.36 ?  124 SER S O   1 
ATOM   8124 C CB  . SER E 5 137 ? 126.706 171.359 149.053 1.00 119.61 ?  124 SER S CB  1 
ATOM   8125 O OG  . SER E 5 137 ? 127.977 170.946 148.585 1.00 117.02 ?  124 SER S OG  1 
ATOM   8126 N N   . ASP E 5 138 ? 128.511 171.288 152.014 1.00 120.96 ?  125 ASP S N   1 
ATOM   8127 C CA  . ASP E 5 138 ? 129.121 170.411 152.998 1.00 117.35 ?  125 ASP S CA  1 
ATOM   8128 C C   . ASP E 5 138 ? 128.351 170.465 154.314 1.00 118.65 ?  125 ASP S C   1 
ATOM   8129 O O   . ASP E 5 138 ? 127.625 171.419 154.602 1.00 120.56 ?  125 ASP S O   1 
ATOM   8130 C CB  . ASP E 5 138 ? 130.579 170.800 153.229 1.00 115.45 ?  125 ASP S CB  1 
ATOM   8131 C CG  . ASP E 5 138 ? 131.296 171.153 151.945 1.00 120.88 ?  125 ASP S CG  1 
ATOM   8132 O OD1 . ASP E 5 138 ? 131.108 170.440 150.938 1.00 115.48 ?  125 ASP S OD1 1 
ATOM   8133 O OD2 . ASP E 5 138 ? 132.050 172.147 151.942 1.00 123.15 -1 125 ASP S OD2 1 
ATOM   8134 N N   . ILE E 5 139 ? 128.520 169.422 155.117 1.00 103.64 ?  126 ILE S N   1 
ATOM   8135 C CA  . ILE E 5 139 ? 127.855 169.342 156.411 1.00 100.21 ?  126 ILE S CA  1 
ATOM   8136 C C   . ILE E 5 139 ? 128.607 170.210 157.407 1.00 102.64 ?  126 ILE S C   1 
ATOM   8137 O O   . ILE E 5 139 ? 129.815 170.044 157.604 1.00 105.43 ?  126 ILE S O   1 
ATOM   8138 C CB  . ILE E 5 139 ? 127.781 167.887 156.898 1.00 96.60  ?  126 ILE S CB  1 
ATOM   8139 C CG1 . ILE E 5 139 ? 126.752 167.105 156.093 1.00 102.12 ?  126 ILE S CG1 1 
ATOM   8140 C CG2 . ILE E 5 139 ? 127.422 167.839 158.364 1.00 97.47  ?  126 ILE S CG2 1 
ATOM   8141 C CD1 . ILE E 5 139 ? 127.338 166.364 154.941 1.00 102.00 ?  126 ILE S CD1 1 
ATOM   8142 N N   . VAL E 5 140 ? 127.900 171.139 158.037 1.00 98.28  ?  127 VAL S N   1 
ATOM   8143 C CA  . VAL E 5 140 ? 128.474 171.953 159.099 1.00 100.83 ?  127 VAL S CA  1 
ATOM   8144 C C   . VAL E 5 140 ? 128.306 171.193 160.405 1.00 98.99  ?  127 VAL S C   1 
ATOM   8145 O O   . VAL E 5 140 ? 127.183 170.891 160.818 1.00 104.98 ?  127 VAL S O   1 
ATOM   8146 C CB  . VAL E 5 140 ? 127.813 173.336 159.170 1.00 102.92 ?  127 VAL S CB  1 
ATOM   8147 C CG1 . VAL E 5 140 ? 128.120 173.999 160.499 1.00 101.59 ?  127 VAL S CG1 1 
ATOM   8148 C CG2 . VAL E 5 140 ? 128.288 174.202 158.020 1.00 103.10 ?  127 VAL S CG2 1 
ATOM   8149 N N   . MET E 5 141 ? 129.419 170.878 161.049 1.00 94.90  ?  128 MET S N   1 
ATOM   8150 C CA  . MET E 5 141 ? 129.432 170.030 162.232 1.00 95.22  ?  128 MET S CA  1 
ATOM   8151 C C   . MET E 5 141 ? 129.685 170.962 163.412 1.00 99.14  ?  128 MET S C   1 
ATOM   8152 O O   . MET E 5 141 ? 130.829 171.332 163.684 1.00 108.99 ?  128 MET S O   1 
ATOM   8153 C CB  . MET E 5 141 ? 130.512 168.959 162.104 1.00 97.97  ?  128 MET S CB  1 
ATOM   8154 C CG  . MET E 5 141 ? 130.139 167.779 161.201 1.00 100.08 ?  128 MET S CG  1 
ATOM   8155 S SD  . MET E 5 141 ? 128.749 166.743 161.670 1.00 114.96 ?  128 MET S SD  1 
ATOM   8156 C CE  . MET E 5 141 ? 128.922 166.719 163.436 1.00 98.32  ?  128 MET S CE  1 
ATOM   8157 N N   . THR E 5 142 ? 128.621 171.351 164.104 1.00 105.69 ?  129 THR S N   1 
ATOM   8158 C CA  . THR E 5 142 ? 128.691 172.392 165.122 1.00 109.05 ?  129 THR S CA  1 
ATOM   8159 C C   . THR E 5 142 ? 128.896 171.772 166.496 1.00 106.68 ?  129 THR S C   1 
ATOM   8160 O O   . THR E 5 142 ? 128.162 170.859 166.886 1.00 112.19 ?  129 THR S O   1 
ATOM   8161 C CB  . THR E 5 142 ? 127.419 173.241 165.120 1.00 105.32 ?  129 THR S CB  1 
ATOM   8162 O OG1 . THR E 5 142 ? 127.114 173.641 163.780 1.00 108.61 ?  129 THR S OG1 1 
ATOM   8163 C CG2 . THR E 5 142 ? 127.608 174.477 165.978 1.00 101.80 ?  129 THR S CG2 1 
ATOM   8164 N N   . GLN E 5 143 ? 129.889 172.272 167.229 1.00 106.93 ?  130 GLN S N   1 
ATOM   8165 C CA  . GLN E 5 143 ? 130.178 171.784 168.570 1.00 110.89 ?  130 GLN S CA  1 
ATOM   8166 C C   . GLN E 5 143 ? 129.837 172.793 169.658 1.00 114.87 ?  130 GLN S C   1 
ATOM   8167 O O   . GLN E 5 143 ? 130.185 172.567 170.822 1.00 114.59 ?  130 GLN S O   1 
ATOM   8168 C CB  . GLN E 5 143 ? 131.644 171.367 168.682 1.00 110.71 ?  130 GLN S CB  1 
ATOM   8169 C CG  . GLN E 5 143 ? 131.820 169.866 168.788 1.00 108.55 ?  130 GLN S CG  1 
ATOM   8170 C CD  . GLN E 5 143 ? 133.264 169.448 168.876 1.00 109.63 ?  130 GLN S CD  1 
ATOM   8171 O OE1 . GLN E 5 143 ? 133.915 169.222 167.861 1.00 110.05 ?  130 GLN S OE1 1 
ATOM   8172 N NE2 . GLN E 5 143 ? 133.773 169.334 170.093 1.00 114.40 ?  130 GLN S NE2 1 
ATOM   8173 N N   . ALA E 5 144 ? 129.171 173.895 169.309 1.00 135.22 ?  131 ALA S N   1 
ATOM   8174 C CA  . ALA E 5 144 ? 128.649 174.847 170.285 1.00 133.68 ?  131 ALA S CA  1 
ATOM   8175 C C   . ALA E 5 144 ? 129.812 175.175 171.212 1.00 133.00 ?  131 ALA S C   1 
ATOM   8176 O O   . ALA E 5 144 ? 130.841 175.694 170.768 1.00 131.39 ?  131 ALA S O   1 
ATOM   8177 C CB  . ALA E 5 144 ? 127.479 174.232 171.058 1.00 129.96 ?  131 ALA S CB  1 
ATOM   8178 N N   . THR E 5 145 ? 129.649 174.887 172.503 1.00 132.93 ?  132 THR S N   1 
ATOM   8179 C CA  . THR E 5 145 ? 130.694 175.172 173.475 1.00 131.74 ?  132 THR S CA  1 
ATOM   8180 C C   . THR E 5 145 ? 132.102 174.812 173.022 1.00 131.21 ?  132 THR S C   1 
ATOM   8181 O O   . THR E 5 145 ? 132.317 173.805 172.345 1.00 130.98 ?  132 THR S O   1 
ATOM   8182 C CB  . THR E 5 145 ? 130.387 174.499 174.814 1.00 132.39 ?  132 THR S CB  1 
ATOM   8183 O OG1 . THR E 5 145 ? 131.492 174.686 175.706 1.00 133.67 ?  132 THR S OG1 1 
ATOM   8184 C CG2 . THR E 5 145 ? 130.147 173.013 174.623 1.00 129.32 ?  132 THR S CG2 1 
ATOM   8185 N N   . SER E 5 146 ? 133.064 175.657 173.395 1.00 130.24 ?  133 SER S N   1 
ATOM   8186 C CA  . SER E 5 146 ? 134.453 175.462 173.013 1.00 131.99 ?  133 SER S CA  1 
ATOM   8187 C C   . SER E 5 146 ? 135.357 175.059 174.166 1.00 133.25 ?  133 SER S C   1 
ATOM   8188 O O   . SER E 5 146 ? 136.422 174.486 173.918 1.00 133.57 ?  133 SER S O   1 
ATOM   8189 C CB  . SER E 5 146 ? 135.011 176.739 172.370 1.00 130.17 ?  133 SER S CB  1 
ATOM   8190 O OG  . SER E 5 146 ? 134.003 177.420 171.643 1.00 131.17 ?  133 SER S OG  1 
ATOM   8191 N N   . SER E 5 147 ? 134.967 175.338 175.408 1.00 132.61 ?  134 SER S N   1 
ATOM   8192 C CA  . SER E 5 147 ? 135.791 174.996 176.559 1.00 132.48 ?  134 SER S CA  1 
ATOM   8193 C C   . SER E 5 147 ? 134.912 174.947 177.797 1.00 131.58 ?  134 SER S C   1 
ATOM   8194 O O   . SER E 5 147 ? 134.217 175.920 178.101 1.00 131.65 ?  134 SER S O   1 
ATOM   8195 C CB  . SER E 5 147 ? 136.921 176.012 176.749 1.00 131.60 ?  134 SER S CB  1 
ATOM   8196 O OG  . SER E 5 147 ? 137.419 175.973 178.074 1.00 132.34 ?  134 SER S OG  1 
ATOM   8197 N N   . VAL E 5 148 ? 134.945 173.821 178.504 1.00 140.60 ?  135 VAL S N   1 
ATOM   8198 C CA  . VAL E 5 148 ? 134.186 173.673 179.743 1.00 143.51 ?  135 VAL S CA  1 
ATOM   8199 C C   . VAL E 5 148 ? 135.133 173.243 180.857 1.00 142.75 ?  135 VAL S C   1 
ATOM   8200 O O   . VAL E 5 148 ? 136.038 172.430 180.624 1.00 140.84 ?  135 VAL S O   1 
ATOM   8201 C CB  . VAL E 5 148 ? 133.027 172.675 179.578 1.00 142.00 ?  135 VAL S CB  1 
ATOM   8202 C CG1 . VAL E 5 148 ? 132.025 173.190 178.561 1.00 140.81 ?  135 VAL S CG1 1 
ATOM   8203 C CG2 . VAL E 5 148 ? 133.546 171.311 179.165 1.00 141.09 ?  135 VAL S CG2 1 
ATOM   8204 N N   . PRO E 5 149 ? 134.973 173.762 182.073 1.00 152.64 ?  136 PRO S N   1 
ATOM   8205 C CA  . PRO E 5 149 ? 135.847 173.340 183.173 1.00 151.85 ?  136 PRO S CA  1 
ATOM   8206 C C   . PRO E 5 149 ? 135.351 172.065 183.832 1.00 151.10 ?  136 PRO S C   1 
ATOM   8207 O O   . PRO E 5 149 ? 134.153 171.918 184.093 1.00 150.24 ?  136 PRO S O   1 
ATOM   8208 C CB  . PRO E 5 149 ? 135.798 174.532 184.133 1.00 151.26 ?  136 PRO S CB  1 
ATOM   8209 C CG  . PRO E 5 149 ? 134.460 175.162 183.885 1.00 151.17 ?  136 PRO S CG  1 
ATOM   8210 C CD  . PRO E 5 149 ? 133.999 174.783 182.496 1.00 150.14 ?  136 PRO S CD  1 
ATOM   8211 N N   . VAL E 5 150 ? 136.265 171.133 184.102 1.00 152.07 ?  137 VAL S N   1 
ATOM   8212 C CA  . VAL E 5 150 ? 135.921 169.844 184.683 1.00 154.35 ?  137 VAL S CA  1 
ATOM   8213 C C   . VAL E 5 150 ? 136.843 169.569 185.861 1.00 152.99 ?  137 VAL S C   1 
ATOM   8214 O O   . VAL E 5 150 ? 137.890 170.198 186.026 1.00 152.54 ?  137 VAL S O   1 
ATOM   8215 C CB  . VAL E 5 150 ? 136.010 168.692 183.657 1.00 154.89 ?  137 VAL S CB  1 
ATOM   8216 C CG1 . VAL E 5 150 ? 135.032 168.914 182.516 1.00 153.29 ?  137 VAL S CG1 1 
ATOM   8217 C CG2 . VAL E 5 150 ? 137.427 168.565 183.129 1.00 152.80 ?  137 VAL S CG2 1 
ATOM   8218 N N   . THR E 5 151 ? 136.430 168.618 186.691 1.00 152.31 ?  138 THR S N   1 
ATOM   8219 C CA  . THR E 5 151 ? 137.203 168.163 187.832 1.00 153.42 ?  138 THR S CA  1 
ATOM   8220 C C   . THR E 5 151 ? 137.265 166.644 187.828 1.00 154.10 ?  138 THR S C   1 
ATOM   8221 O O   . THR E 5 151 ? 136.317 165.982 187.395 1.00 151.45 ?  138 THR S O   1 
ATOM   8222 C CB  . THR E 5 151 ? 136.588 168.652 189.152 1.00 153.44 ?  138 THR S CB  1 
ATOM   8223 O OG1 . THR E 5 151 ? 137.127 167.899 190.246 1.00 152.39 ?  138 THR S OG1 1 
ATOM   8224 C CG2 . THR E 5 151 ? 135.076 168.494 189.128 1.00 151.50 ?  138 THR S CG2 1 
ATOM   8225 N N   . PRO E 5 152 ? 138.373 166.066 188.293 1.00 153.23 ?  139 PRO S N   1 
ATOM   8226 C CA  . PRO E 5 152 ? 138.488 164.603 188.305 1.00 150.89 ?  139 PRO S CA  1 
ATOM   8227 C C   . PRO E 5 152 ? 137.394 163.960 189.144 1.00 150.56 ?  139 PRO S C   1 
ATOM   8228 O O   . PRO E 5 152 ? 136.980 164.491 190.176 1.00 150.22 ?  139 PRO S O   1 
ATOM   8229 C CB  . PRO E 5 152 ? 139.876 164.363 188.908 1.00 147.56 ?  139 PRO S CB  1 
ATOM   8230 C CG  . PRO E 5 152 ? 140.634 165.605 188.601 1.00 147.84 ?  139 PRO S CG  1 
ATOM   8231 C CD  . PRO E 5 152 ? 139.636 166.723 188.670 1.00 149.68 ?  139 PRO S CD  1 
ATOM   8232 N N   . GLY E 5 153 ? 136.923 162.804 188.682 1.00 148.81 ?  140 GLY S N   1 
ATOM   8233 C CA  . GLY E 5 153 ? 135.865 162.080 189.350 1.00 147.27 ?  140 GLY S CA  1 
ATOM   8234 C C   . GLY E 5 153 ? 134.461 162.480 188.957 1.00 148.81 ?  140 GLY S C   1 
ATOM   8235 O O   . GLY E 5 153 ? 133.504 161.846 189.417 1.00 148.44 ?  140 GLY S O   1 
ATOM   8236 N N   . GLU E 5 154 ? 134.304 163.501 188.121 1.00 145.79 ?  141 GLU S N   1 
ATOM   8237 C CA  . GLU E 5 154 ? 132.991 163.990 187.737 1.00 145.23 ?  141 GLU S CA  1 
ATOM   8238 C C   . GLU E 5 154 ? 132.562 163.345 186.419 1.00 146.59 ?  141 GLU S C   1 
ATOM   8239 O O   . GLU E 5 154 ? 133.237 162.464 185.881 1.00 145.07 ?  141 GLU S O   1 
ATOM   8240 C CB  . GLU E 5 154 ? 133.007 165.514 187.643 1.00 146.46 ?  141 GLU S CB  1 
ATOM   8241 C CG  . GLU E 5 154 ? 131.758 166.188 188.181 1.00 147.22 ?  141 GLU S CG  1 
ATOM   8242 C CD  . GLU E 5 154 ? 131.799 167.695 188.026 1.00 149.23 ?  141 GLU S CD  1 
ATOM   8243 O OE1 . GLU E 5 154 ? 131.919 168.172 186.879 1.00 149.27 ?  141 GLU S OE1 1 
ATOM   8244 O OE2 . GLU E 5 154 ? 131.715 168.403 189.051 1.00 148.08 -1 141 GLU S OE2 1 
ATOM   8245 N N   . SER E 5 155 ? 131.422 163.782 185.888 1.00 140.38 ?  142 SER S N   1 
ATOM   8246 C CA  . SER E 5 155 ? 130.920 163.323 184.601 1.00 140.37 ?  142 SER S CA  1 
ATOM   8247 C C   . SER E 5 155 ? 130.601 164.536 183.743 1.00 139.50 ?  142 SER S C   1 
ATOM   8248 O O   . SER E 5 155 ? 129.935 165.467 184.206 1.00 137.45 ?  142 SER S O   1 
ATOM   8249 C CB  . SER E 5 155 ? 129.676 162.448 184.768 1.00 138.70 ?  142 SER S CB  1 
ATOM   8250 O OG  . SER E 5 155 ? 130.030 161.116 185.090 1.00 139.47 ?  142 SER S OG  1 
ATOM   8251 N N   . VAL E 5 156 ? 131.075 164.526 182.500 1.00 131.71 ?  143 VAL S N   1 
ATOM   8252 C CA  . VAL E 5 156 ? 130.870 165.628 181.569 1.00 130.41 ?  143 VAL S CA  1 
ATOM   8253 C C   . VAL E 5 156 ? 130.334 165.062 180.263 1.00 128.01 ?  143 VAL S C   1 
ATOM   8254 O O   . VAL E 5 156 ? 130.833 164.044 179.771 1.00 127.79 ?  143 VAL S O   1 
ATOM   8255 C CB  . VAL E 5 156 ? 132.170 166.421 181.333 1.00 130.85 ?  143 VAL S CB  1 
ATOM   8256 C CG1 . VAL E 5 156 ? 133.330 165.478 181.085 1.00 128.39 ?  143 VAL S CG1 1 
ATOM   8257 C CG2 . VAL E 5 156 ? 132.006 167.392 180.176 1.00 128.94 ?  143 VAL S CG2 1 
ATOM   8258 N N   . SER E 5 157 ? 129.309 165.707 179.715 1.00 120.67 ?  144 SER S N   1 
ATOM   8259 C CA  . SER E 5 157 ? 128.711 165.318 178.444 1.00 120.96 ?  144 SER S CA  1 
ATOM   8260 C C   . SER E 5 157 ? 129.063 166.376 177.406 1.00 120.37 ?  144 SER S C   1 
ATOM   8261 O O   . SER E 5 157 ? 128.595 167.516 177.491 1.00 122.08 ?  144 SER S O   1 
ATOM   8262 C CB  . SER E 5 157 ? 127.199 165.161 178.576 1.00 122.12 ?  144 SER S CB  1 
ATOM   8263 O OG  . SER E 5 157 ? 126.872 163.969 179.266 1.00 123.91 ?  144 SER S OG  1 
ATOM   8264 N N   . ILE E 5 158 ? 129.885 166.000 176.433 1.00 114.16 ?  145 ILE S N   1 
ATOM   8265 C CA  . ILE E 5 158 ? 130.284 166.897 175.356 1.00 109.47 ?  145 ILE S CA  1 
ATOM   8266 C C   . ILE E 5 158 ? 129.280 166.767 174.221 1.00 107.22 ?  145 ILE S C   1 
ATOM   8267 O O   . ILE E 5 158 ? 129.037 165.665 173.719 1.00 109.23 ?  145 ILE S O   1 
ATOM   8268 C CB  . ILE E 5 158 ? 131.708 166.579 174.874 1.00 111.71 ?  145 ILE S CB  1 
ATOM   8269 C CG1 . ILE E 5 158 ? 132.713 166.831 175.996 1.00 113.01 ?  145 ILE S CG1 1 
ATOM   8270 C CG2 . ILE E 5 158 ? 132.051 167.406 173.653 1.00 109.51 ?  145 ILE S CG2 1 
ATOM   8271 C CD1 . ILE E 5 158 ? 134.147 166.827 175.540 1.00 112.05 ?  145 ILE S CD1 1 
ATOM   8272 N N   . SER E 5 159 ? 128.700 167.889 173.815 1.00 110.14 ?  146 SER S N   1 
ATOM   8273 C CA  . SER E 5 159 ? 127.628 167.900 172.833 1.00 110.81 ?  146 SER S CA  1 
ATOM   8274 C C   . SER E 5 159 ? 128.159 168.274 171.457 1.00 110.28 ?  146 SER S C   1 
ATOM   8275 O O   . SER E 5 159 ? 129.156 168.987 171.325 1.00 117.78 ?  146 SER S O   1 
ATOM   8276 C CB  . SER E 5 159 ? 126.527 168.879 173.241 1.00 114.49 ?  146 SER S CB  1 
ATOM   8277 O OG  . SER E 5 159 ? 127.079 170.071 173.771 1.00 114.30 ?  146 SER S OG  1 
ATOM   8278 N N   . CYS E 5 160 ? 127.479 167.778 170.429 1.00 103.63 ?  147 CYS S N   1 
ATOM   8279 C CA  . CYS E 5 160 ? 127.830 168.084 169.052 1.00 102.11 ?  147 CYS S CA  1 
ATOM   8280 C C   . CYS E 5 160 ? 126.565 168.026 168.213 1.00 108.79 ?  147 CYS S C   1 
ATOM   8281 O O   . CYS E 5 160 ? 125.690 167.193 168.459 1.00 117.68 ?  147 CYS S O   1 
ATOM   8282 C CB  . CYS E 5 160 ? 128.885 167.109 168.523 1.00 108.64 ?  147 CYS S CB  1 
ATOM   8283 S SG  . CYS E 5 160 ? 129.145 167.168 166.748 1.00 125.82 ?  147 CYS S SG  1 
ATOM   8284 N N   . ARG E 5 161 ? 126.467 168.919 167.233 1.00 112.62 ?  148 ARG S N   1 
ATOM   8285 C CA  . ARG E 5 161 ? 125.303 168.997 166.364 1.00 110.38 ?  148 ARG S CA  1 
ATOM   8286 C C   . ARG E 5 161 ? 125.745 168.929 164.913 1.00 109.06 ?  148 ARG S C   1 
ATOM   8287 O O   . ARG E 5 161 ? 126.861 169.321 164.567 1.00 115.31 ?  148 ARG S O   1 
ATOM   8288 C CB  . ARG E 5 161 ? 124.507 170.286 166.593 1.00 109.77 ?  148 ARG S CB  1 
ATOM   8289 C CG  . ARG E 5 161 ? 124.218 170.598 168.048 1.00 113.45 ?  148 ARG S CG  1 
ATOM   8290 C CD  . ARG E 5 161 ? 123.314 171.827 168.341 1.00 114.89 ?  148 ARG S CD  1 
ATOM   8291 N NE  . ARG E 5 161 ? 123.553 173.055 167.581 1.00 119.82 ?  148 ARG S NE  1 
ATOM   8292 C CZ  . ARG E 5 161 ? 123.281 173.253 166.296 1.00 118.17 ?  148 ARG S CZ  1 
ATOM   8293 N NH1 . ARG E 5 161 ? 122.599 172.370 165.584 1.00 116.21 1  148 ARG S NH1 1 
ATOM   8294 N NH2 . ARG E 5 161 ? 123.658 174.392 165.722 1.00 114.74 ?  148 ARG S NH2 1 
ATOM   8295 N N   . SER E 5 162 ? 124.854 168.433 164.064 1.00 92.17  ?  149 SER S N   1 
ATOM   8296 C CA  . SER E 5 162 ? 125.117 168.293 162.641 1.00 92.38  ?  149 SER S CA  1 
ATOM   8297 C C   . SER E 5 162 ? 124.066 169.052 161.847 1.00 100.20 ?  149 SER S C   1 
ATOM   8298 O O   . SER E 5 162 ? 122.889 169.070 162.216 1.00 107.71 ?  149 SER S O   1 
ATOM   8299 C CB  . SER E 5 162 ? 125.123 166.825 162.224 1.00 94.69  ?  149 SER S CB  1 
ATOM   8300 O OG  . SER E 5 162 ? 124.925 166.701 160.829 1.00 95.69  ?  149 SER S OG  1 
ATOM   8301 N N   . SER E 5 163 ? 124.499 169.688 160.758 1.00 95.69  ?  150 SER S N   1 
ATOM   8302 C CA  . SER E 5 163 ? 123.556 170.391 159.896 1.00 93.24  ?  150 SER S CA  1 
ATOM   8303 C C   . SER E 5 163 ? 122.659 169.413 159.149 1.00 97.72  ?  150 SER S C   1 
ATOM   8304 O O   . SER E 5 163 ? 121.490 169.713 158.882 1.00 99.43  ?  150 SER S O   1 
ATOM   8305 C CB  . SER E 5 163 ? 124.308 171.289 158.917 1.00 93.58  ?  150 SER S CB  1 
ATOM   8306 O OG  . SER E 5 163 ? 124.459 170.657 157.660 1.00 95.77  ?  150 SER S OG  1 
ATOM   8307 N N   . LYS E 5 164 ? 123.185 168.244 158.803 1.00 102.66 ?  151 LYS S N   1 
ATOM   8308 C CA  . LYS E 5 164 ? 122.441 167.212 158.100 1.00 101.97 ?  151 LYS S CA  1 
ATOM   8309 C C   . LYS E 5 164 ? 122.360 165.963 158.968 1.00 105.08 ?  151 LYS S C   1 
ATOM   8310 O O   . LYS E 5 164 ? 123.238 165.708 159.794 1.00 110.03 ?  151 LYS S O   1 
ATOM   8311 C CB  . LYS E 5 164 ? 123.100 166.877 156.757 1.00 97.87  ?  151 LYS S CB  1 
ATOM   8312 C CG  . LYS E 5 164 ? 122.250 166.030 155.835 1.00 96.56  ?  151 LYS S CG  1 
ATOM   8313 C CD  . LYS E 5 164 ? 123.113 165.129 154.977 1.00 102.17 ?  151 LYS S CD  1 
ATOM   8314 C CE  . LYS E 5 164 ? 122.939 165.435 153.503 1.00 100.71 ?  151 LYS S CE  1 
ATOM   8315 N NZ  . LYS E 5 164 ? 122.841 164.188 152.698 1.00 101.66 1  151 LYS S NZ  1 
ATOM   8316 N N   . SER E 5 165 ? 121.293 165.191 158.782 1.00 101.97 ?  152 SER S N   1 
ATOM   8317 C CA  . SER E 5 165 ? 121.122 163.954 159.533 1.00 103.60 ?  152 SER S CA  1 
ATOM   8318 C C   . SER E 5 165 ? 122.194 162.950 159.134 1.00 110.63 ?  152 SER S C   1 
ATOM   8319 O O   . SER E 5 165 ? 122.313 162.592 157.958 1.00 106.18 ?  152 SER S O   1 
ATOM   8320 C CB  . SER E 5 165 ? 119.732 163.376 159.292 1.00 105.48 ?  152 SER S CB  1 
ATOM   8321 O OG  . SER E 5 165 ? 119.416 162.395 160.264 1.00 106.64 ?  152 SER S OG  1 
ATOM   8322 N N   . LEU E 5 166 ? 122.971 162.491 160.114 1.00 102.05 ?  153 LEU S N   1 
ATOM   8323 C CA  . LEU E 5 166 ? 124.021 161.515 159.858 1.00 91.97  ?  153 LEU S CA  1 
ATOM   8324 C C   . LEU E 5 166 ? 123.504 160.086 159.834 1.00 92.49  ?  153 LEU S C   1 
ATOM   8325 O O   . LEU E 5 166 ? 124.266 159.177 159.491 1.00 96.17  ?  153 LEU S O   1 
ATOM   8326 C CB  . LEU E 5 166 ? 125.126 161.650 160.904 1.00 88.29  ?  153 LEU S CB  1 
ATOM   8327 C CG  . LEU E 5 166 ? 125.831 163.006 160.916 1.00 84.79  ?  153 LEU S CG  1 
ATOM   8328 C CD1 . LEU E 5 166 ? 127.081 162.958 161.760 1.00 82.49  ?  153 LEU S CD1 1 
ATOM   8329 C CD2 . LEU E 5 166 ? 126.162 163.441 159.503 1.00 89.97  ?  153 LEU S CD2 1 
ATOM   8330 N N   . LEU E 5 167 ? 122.240 159.867 160.183 1.00 100.93 ?  154 LEU S N   1 
ATOM   8331 C CA  . LEU E 5 167 ? 121.655 158.537 160.101 1.00 99.63  ?  154 LEU S CA  1 
ATOM   8332 C C   . LEU E 5 167 ? 121.462 158.148 158.642 1.00 97.10  ?  154 LEU S C   1 
ATOM   8333 O O   . LEU E 5 167 ? 120.944 158.932 157.843 1.00 98.67  ?  154 LEU S O   1 
ATOM   8334 C CB  . LEU E 5 167 ? 120.323 158.504 160.847 1.00 93.77  ?  154 LEU S CB  1 
ATOM   8335 C CG  . LEU E 5 167 ? 119.931 157.220 161.578 1.00 94.29  ?  154 LEU S CG  1 
ATOM   8336 C CD1 . LEU E 5 167 ? 118.808 157.501 162.556 1.00 96.22  ?  154 LEU S CD1 1 
ATOM   8337 C CD2 . LEU E 5 167 ? 119.520 156.137 160.609 1.00 92.67  ?  154 LEU S CD2 1 
ATOM   8338 N N   . HIS E 5 168 ? 121.880 156.939 158.295 1.00 92.26  ?  155 HIS S N   1 
ATOM   8339 C CA  . HIS E 5 168 ? 121.803 156.439 156.932 1.00 87.45  ?  155 HIS S CA  1 
ATOM   8340 C C   . HIS E 5 168 ? 120.779 155.316 156.843 1.00 97.20  ?  155 HIS S C   1 
ATOM   8341 O O   . HIS E 5 168 ? 120.282 154.808 157.850 1.00 105.46 ?  155 HIS S O   1 
ATOM   8342 C CB  . HIS E 5 168 ? 123.175 155.953 156.458 1.00 92.96  ?  155 HIS S CB  1 
ATOM   8343 C CG  . HIS E 5 168 ? 123.326 155.925 154.970 1.00 94.71  ?  155 HIS S CG  1 
ATOM   8344 N ND1 . HIS E 5 168 ? 123.091 154.794 154.221 1.00 96.84  ?  155 HIS S ND1 1 
ATOM   8345 C CD2 . HIS E 5 168 ? 123.691 156.888 154.093 1.00 97.53  ?  155 HIS S CD2 1 
ATOM   8346 C CE1 . HIS E 5 168 ? 123.305 155.061 152.946 1.00 94.06  ?  155 HIS S CE1 1 
ATOM   8347 N NE2 . HIS E 5 168 ? 123.670 156.325 152.841 1.00 99.14  ?  155 HIS S NE2 1 
ATOM   8348 N N   . SER E 5 169 ? 120.467 154.928 155.605 1.00 100.82 ?  156 SER S N   1 
ATOM   8349 C CA  . SER E 5 169 ? 119.510 153.850 155.389 1.00 104.33 ?  156 SER S CA  1 
ATOM   8350 C C   . SER E 5 169 ? 120.020 152.524 155.936 1.00 103.25 ?  156 SER S C   1 
ATOM   8351 O O   . SER E 5 169 ? 119.217 151.643 156.263 1.00 104.07 ?  156 SER S O   1 
ATOM   8352 C CB  . SER E 5 169 ? 119.191 153.724 153.901 1.00 101.82 ?  156 SER S CB  1 
ATOM   8353 O OG  . SER E 5 169 ? 120.254 153.101 153.204 1.00 101.63 ?  156 SER S OG  1 
ATOM   8354 N N   . ASN E 5 170 ? 121.342 152.356 156.040 1.00 93.49  ?  157 ASN S N   1 
ATOM   8355 C CA  . ASN E 5 170 ? 121.890 151.136 156.621 1.00 90.16  ?  157 ASN S CA  1 
ATOM   8356 C C   . ASN E 5 170 ? 121.543 150.992 158.093 1.00 95.45  ?  157 ASN S C   1 
ATOM   8357 O O   . ASN E 5 170 ? 121.597 149.878 158.623 1.00 101.70 ?  157 ASN S O   1 
ATOM   8358 C CB  . ASN E 5 170 ? 123.410 151.092 156.469 1.00 92.34  ?  157 ASN S CB  1 
ATOM   8359 C CG  . ASN E 5 170 ? 123.902 151.854 155.268 1.00 95.37  ?  157 ASN S CG  1 
ATOM   8360 O OD1 . ASN E 5 170 ? 124.504 152.914 155.403 1.00 94.80  ?  157 ASN S OD1 1 
ATOM   8361 N ND2 . ASN E 5 170 ? 123.665 151.311 154.083 1.00 100.15 ?  157 ASN S ND2 1 
ATOM   8362 N N   . GLY E 5 171 ? 121.203 152.085 158.767 1.00 78.73  ?  158 GLY S N   1 
ATOM   8363 C CA  . GLY E 5 171 ? 120.886 152.050 160.175 1.00 84.08  ?  158 GLY S CA  1 
ATOM   8364 C C   . GLY E 5 171 ? 121.997 152.497 161.095 1.00 87.64  ?  158 GLY S C   1 
ATOM   8365 O O   . GLY E 5 171 ? 121.818 152.450 162.317 1.00 94.58  ?  158 GLY S O   1 
ATOM   8366 N N   . ASN E 5 172 ? 123.133 152.928 160.557 1.00 85.76  ?  159 ASN S N   1 
ATOM   8367 C CA  . ASN E 5 172 ? 124.246 153.410 161.360 1.00 88.90  ?  159 ASN S CA  1 
ATOM   8368 C C   . ASN E 5 172 ? 124.467 154.885 161.072 1.00 83.25  ?  159 ASN S C   1 
ATOM   8369 O O   . ASN E 5 172 ? 124.497 155.296 159.909 1.00 83.12  ?  159 ASN S O   1 
ATOM   8370 C CB  . ASN E 5 172 ? 125.522 152.615 161.076 1.00 90.12  ?  159 ASN S CB  1 
ATOM   8371 C CG  . ASN E 5 172 ? 125.654 152.229 159.626 1.00 87.54  ?  159 ASN S CG  1 
ATOM   8372 O OD1 . ASN E 5 172 ? 124.944 152.749 158.770 1.00 87.56  ?  159 ASN S OD1 1 
ATOM   8373 N ND2 . ASN E 5 172 ? 126.561 151.307 159.339 1.00 79.30  ?  159 ASN S ND2 1 
ATOM   8374 N N   . THR E 5 173 ? 124.609 155.675 162.129 1.00 80.03  ?  160 THR S N   1 
ATOM   8375 C CA  . THR E 5 173 ? 124.912 157.093 162.003 1.00 88.67  ?  160 THR S CA  1 
ATOM   8376 C C   . THR E 5 173 ? 126.424 157.265 161.975 1.00 92.85  ?  160 THR S C   1 
ATOM   8377 O O   . THR E 5 173 ? 127.117 156.839 162.902 1.00 92.78  ?  160 THR S O   1 
ATOM   8378 C CB  . THR E 5 173 ? 124.301 157.888 163.153 1.00 89.92  ?  160 THR S CB  1 
ATOM   8379 O OG1 . THR E 5 173 ? 125.188 157.858 164.275 1.00 97.04  ?  160 THR S OG1 1 
ATOM   8380 C CG2 . THR E 5 173 ? 122.978 157.283 163.563 1.00 84.33  ?  160 THR S CG2 1 
ATOM   8381 N N   . TYR E 5 174 ? 126.931 157.892 160.917 1.00 84.40  ?  161 TYR S N   1 
ATOM   8382 C CA  . TYR E 5 174 ? 128.370 158.006 160.698 1.00 72.33  ?  161 TYR S CA  1 
ATOM   8383 C C   . TYR E 5 174 ? 128.893 159.257 161.394 1.00 78.89  ?  161 TYR S C   1 
ATOM   8384 O O   . TYR E 5 174 ? 129.096 160.309 160.789 1.00 90.20  ?  161 TYR S O   1 
ATOM   8385 C CB  . TYR E 5 174 ? 128.676 158.030 159.209 1.00 72.64  ?  161 TYR S CB  1 
ATOM   8386 C CG  . TYR E 5 174 ? 128.276 156.774 158.485 1.00 77.59  ?  161 TYR S CG  1 
ATOM   8387 C CD1 . TYR E 5 174 ? 129.043 155.629 158.572 1.00 85.64  ?  161 TYR S CD1 1 
ATOM   8388 C CD2 . TYR E 5 174 ? 127.132 156.735 157.711 1.00 78.95  ?  161 TYR S CD2 1 
ATOM   8389 C CE1 . TYR E 5 174 ? 128.683 154.482 157.910 1.00 83.89  ?  161 TYR S CE1 1 
ATOM   8390 C CE2 . TYR E 5 174 ? 126.765 155.592 157.045 1.00 80.12  ?  161 TYR S CE2 1 
ATOM   8391 C CZ  . TYR E 5 174 ? 127.545 154.468 157.147 1.00 85.50  ?  161 TYR S CZ  1 
ATOM   8392 O OH  . TYR E 5 174 ? 127.183 153.321 156.484 1.00 93.18  ?  161 TYR S OH  1 
ATOM   8393 N N   . LEU E 5 175 ? 129.124 159.130 162.696 1.00 66.95  ?  162 LEU S N   1 
ATOM   8394 C CA  . LEU E 5 175 ? 129.740 160.190 163.478 1.00 75.28  ?  162 LEU S CA  1 
ATOM   8395 C C   . LEU E 5 175 ? 130.857 159.608 164.328 1.00 80.08  ?  162 LEU S C   1 
ATOM   8396 O O   . LEU E 5 175 ? 130.666 158.590 164.997 1.00 85.09  ?  162 LEU S O   1 
ATOM   8397 C CB  . LEU E 5 175 ? 128.717 160.908 164.357 1.00 69.14  ?  162 LEU S CB  1 
ATOM   8398 C CG  . LEU E 5 175 ? 129.349 162.000 165.213 1.00 69.62  ?  162 LEU S CG  1 
ATOM   8399 C CD1 . LEU E 5 175 ? 128.623 163.304 165.041 1.00 85.47  ?  162 LEU S CD1 1 
ATOM   8400 C CD2 . LEU E 5 175 ? 129.330 161.583 166.659 1.00 75.35  ?  162 LEU S CD2 1 
ATOM   8401 N N   . TYR E 5 176 ? 132.012 160.265 164.308 1.00 79.76  ?  163 TYR S N   1 
ATOM   8402 C CA  . TYR E 5 176 ? 133.216 159.784 164.965 1.00 69.53  ?  163 TYR S CA  1 
ATOM   8403 C C   . TYR E 5 176 ? 133.668 160.801 166.001 1.00 70.99  ?  163 TYR S C   1 
ATOM   8404 O O   . TYR E 5 176 ? 133.529 162.009 165.798 1.00 80.87  ?  163 TYR S O   1 
ATOM   8405 C CB  . TYR E 5 176 ? 134.339 159.543 163.951 1.00 72.11  ?  163 TYR S CB  1 
ATOM   8406 C CG  . TYR E 5 176 ? 134.118 158.365 163.030 1.00 75.40  ?  163 TYR S CG  1 
ATOM   8407 C CD1 . TYR E 5 176 ? 132.999 158.291 162.218 1.00 73.61  ?  163 TYR S CD1 1 
ATOM   8408 C CD2 . TYR E 5 176 ? 135.036 157.335 162.965 1.00 70.66  ?  163 TYR S CD2 1 
ATOM   8409 C CE1 . TYR E 5 176 ? 132.796 157.224 161.384 1.00 72.08  ?  163 TYR S CE1 1 
ATOM   8410 C CE2 . TYR E 5 176 ? 134.842 156.265 162.128 1.00 68.20  ?  163 TYR S CE2 1 
ATOM   8411 C CZ  . TYR E 5 176 ? 133.720 156.214 161.342 1.00 78.96  ?  163 TYR S CZ  1 
ATOM   8412 O OH  . TYR E 5 176 ? 133.524 155.146 160.507 1.00 88.36  ?  163 TYR S OH  1 
ATOM   8413 N N   . TRP E 5 177 ? 134.212 160.310 167.109 1.00 73.83  ?  164 TRP S N   1 
ATOM   8414 C CA  . TRP E 5 177 ? 134.705 161.155 168.187 1.00 71.81  ?  164 TRP S CA  1 
ATOM   8415 C C   . TRP E 5 177 ? 136.202 160.945 168.335 1.00 72.39  ?  164 TRP S C   1 
ATOM   8416 O O   . TRP E 5 177 ? 136.663 159.806 168.445 1.00 84.34  ?  164 TRP S O   1 
ATOM   8417 C CB  . TRP E 5 177 ? 133.998 160.842 169.507 1.00 82.32  ?  164 TRP S CB  1 
ATOM   8418 C CG  . TRP E 5 177 ? 132.645 161.460 169.634 1.00 80.48  ?  164 TRP S CG  1 
ATOM   8419 C CD1 . TRP E 5 177 ? 131.447 160.842 169.464 1.00 78.68  ?  164 TRP S CD1 1 
ATOM   8420 C CD2 . TRP E 5 177 ? 132.351 162.819 169.968 1.00 77.37  ?  164 TRP S CD2 1 
ATOM   8421 N NE1 . TRP E 5 177 ? 130.422 161.729 169.667 1.00 83.71  ?  164 TRP S NE1 1 
ATOM   8422 C CE2 . TRP E 5 177 ? 130.952 162.952 169.975 1.00 80.81  ?  164 TRP S CE2 1 
ATOM   8423 C CE3 . TRP E 5 177 ? 133.134 163.937 170.256 1.00 79.79  ?  164 TRP S CE3 1 
ATOM   8424 C CZ2 . TRP E 5 177 ? 130.321 164.155 170.260 1.00 81.74  ?  164 TRP S CZ2 1 
ATOM   8425 C CZ3 . TRP E 5 177 ? 132.506 165.129 170.540 1.00 82.67  ?  164 TRP S CZ3 1 
ATOM   8426 C CH2 . TRP E 5 177 ? 131.114 165.229 170.540 1.00 83.72  ?  164 TRP S CH2 1 
ATOM   8427 N N   . PHE E 5 178 ? 136.954 162.040 168.344 1.00 69.55  ?  165 PHE S N   1 
ATOM   8428 C CA  . PHE E 5 178 ? 138.399 162.002 168.484 1.00 68.87  ?  165 PHE S CA  1 
ATOM   8429 C C   . PHE E 5 178 ? 138.815 162.832 169.686 1.00 73.83  ?  165 PHE S C   1 
ATOM   8430 O O   . PHE E 5 178 ? 138.165 163.819 170.032 1.00 89.87  ?  165 PHE S O   1 
ATOM   8431 C CB  . PHE E 5 178 ? 139.102 162.533 167.233 1.00 67.08  ?  165 PHE S CB  1 
ATOM   8432 C CG  . PHE E 5 178 ? 138.762 161.784 165.987 1.00 66.65  ?  165 PHE S CG  1 
ATOM   8433 C CD1 . PHE E 5 178 ? 139.455 160.645 165.642 1.00 63.55  ?  165 PHE S CD1 1 
ATOM   8434 C CD2 . PHE E 5 178 ? 137.751 162.220 165.159 1.00 68.94  ?  165 PHE S CD2 1 
ATOM   8435 C CE1 . PHE E 5 178 ? 139.144 159.956 164.500 1.00 65.51  ?  165 PHE S CE1 1 
ATOM   8436 C CE2 . PHE E 5 178 ? 137.438 161.532 164.017 1.00 68.55  ?  165 PHE S CE2 1 
ATOM   8437 C CZ  . PHE E 5 178 ? 138.134 160.399 163.688 1.00 65.62  ?  165 PHE S CZ  1 
ATOM   8438 N N   . LEU E 5 179 ? 139.903 162.419 170.323 1.00 79.74  ?  166 LEU S N   1 
ATOM   8439 C CA  . LEU E 5 179 ? 140.486 163.156 171.432 1.00 84.86  ?  166 LEU S CA  1 
ATOM   8440 C C   . LEU E 5 179 ? 141.919 163.516 171.082 1.00 93.63  ?  166 LEU S C   1 
ATOM   8441 O O   . LEU E 5 179 ? 142.717 162.638 170.743 1.00 103.07 ?  166 LEU S O   1 
ATOM   8442 C CB  . LEU E 5 179 ? 140.445 162.340 172.724 1.00 87.71  ?  166 LEU S CB  1 
ATOM   8443 C CG  . LEU E 5 179 ? 141.503 162.669 173.777 1.00 88.73  ?  166 LEU S CG  1 
ATOM   8444 C CD1 . LEU E 5 179 ? 141.214 163.998 174.442 1.00 88.31  ?  166 LEU S CD1 1 
ATOM   8445 C CD2 . LEU E 5 179 ? 141.572 161.567 174.809 1.00 93.25  ?  166 LEU S CD2 1 
ATOM   8446 N N   . GLN E 5 180 ? 142.240 164.798 171.161 1.00 97.80  ?  167 GLN S N   1 
ATOM   8447 C CA  . GLN E 5 180 ? 143.594 165.287 170.936 1.00 97.63  ?  167 GLN S CA  1 
ATOM   8448 C C   . GLN E 5 180 ? 144.147 165.738 172.281 1.00 103.18 ?  167 GLN S C   1 
ATOM   8449 O O   . GLN E 5 180 ? 143.849 166.840 172.749 1.00 104.11 ?  167 GLN S O   1 
ATOM   8450 C CB  . GLN E 5 180 ? 143.610 166.418 169.915 1.00 94.69  ?  167 GLN S CB  1 
ATOM   8451 C CG  . GLN E 5 180 ? 144.937 167.143 169.826 1.00 99.42  ?  167 GLN S CG  1 
ATOM   8452 C CD  . GLN E 5 180 ? 145.362 167.406 168.405 1.00 102.31 ?  167 GLN S CD  1 
ATOM   8453 O OE1 . GLN E 5 180 ? 144.530 167.591 167.523 1.00 105.51 ?  167 GLN S OE1 1 
ATOM   8454 N NE2 . GLN E 5 180 ? 146.665 167.428 168.173 1.00 100.24 ?  167 GLN S NE2 1 
ATOM   8455 N N   . ARG E 5 181 ? 144.937 164.876 172.909 1.00 103.85 ?  168 ARG S N   1 
ATOM   8456 C CA  . ARG E 5 181 ? 145.588 165.243 174.150 1.00 103.84 ?  168 ARG S CA  1 
ATOM   8457 C C   . ARG E 5 181 ? 146.692 166.262 173.873 1.00 109.71 ?  168 ARG S C   1 
ATOM   8458 O O   . ARG E 5 181 ? 147.265 166.283 172.782 1.00 115.18 ?  168 ARG S O   1 
ATOM   8459 C CB  . ARG E 5 181 ? 146.160 164.007 174.836 1.00 103.61 ?  168 ARG S CB  1 
ATOM   8460 C CG  . ARG E 5 181 ? 145.433 163.642 176.115 1.00 109.53 ?  168 ARG S CG  1 
ATOM   8461 C CD  . ARG E 5 181 ? 145.930 162.332 176.685 1.00 109.38 ?  168 ARG S CD  1 
ATOM   8462 N NE  . ARG E 5 181 ? 145.985 161.290 175.670 1.00 114.95 ?  168 ARG S NE  1 
ATOM   8463 C CZ  . ARG E 5 181 ? 145.119 160.291 175.578 1.00 113.05 ?  168 ARG S CZ  1 
ATOM   8464 N NH1 . ARG E 5 181 ? 144.115 160.167 176.430 1.00 106.18 1  168 ARG S NH1 1 
ATOM   8465 N NH2 . ARG E 5 181 ? 145.265 159.393 174.610 1.00 109.96 ?  168 ARG S NH2 1 
ATOM   8466 N N   . PRO E 5 182 ? 146.998 167.131 174.842 1.00 120.58 ?  169 PRO S N   1 
ATOM   8467 C CA  . PRO E 5 182 ? 147.963 168.209 174.588 1.00 117.99 ?  169 PRO S CA  1 
ATOM   8468 C C   . PRO E 5 182 ? 149.340 167.707 174.195 1.00 120.96 ?  169 PRO S C   1 
ATOM   8469 O O   . PRO E 5 182 ? 150.023 167.049 174.985 1.00 120.46 ?  169 PRO S O   1 
ATOM   8470 C CB  . PRO E 5 182 ? 148.009 168.960 175.925 1.00 116.76 ?  169 PRO S CB  1 
ATOM   8471 C CG  . PRO E 5 182 ? 146.735 168.615 176.601 1.00 117.96 ?  169 PRO S CG  1 
ATOM   8472 C CD  . PRO E 5 182 ? 146.423 167.216 176.194 1.00 118.88 ?  169 PRO S CD  1 
ATOM   8473 N N   . GLY E 5 183 ? 149.755 168.014 172.971 1.00 122.89 ?  170 GLY S N   1 
ATOM   8474 C CA  . GLY E 5 183 ? 151.081 167.682 172.505 1.00 122.46 ?  170 GLY S CA  1 
ATOM   8475 C C   . GLY E 5 183 ? 151.201 166.424 171.676 1.00 124.01 ?  170 GLY S C   1 
ATOM   8476 O O   . GLY E 5 183 ? 152.328 166.013 171.380 1.00 127.31 ?  170 GLY S O   1 
ATOM   8477 N N   . GLN E 5 184 ? 150.092 165.800 171.291 1.00 116.21 ?  171 GLN S N   1 
ATOM   8478 C CA  . GLN E 5 184 ? 150.157 164.577 170.506 1.00 114.85 ?  171 GLN S CA  1 
ATOM   8479 C C   . GLN E 5 184 ? 148.969 164.521 169.554 1.00 110.27 ?  171 GLN S C   1 
ATOM   8480 O O   . GLN E 5 184 ? 148.071 165.364 169.594 1.00 109.92 ?  171 GLN S O   1 
ATOM   8481 C CB  . GLN E 5 184 ? 150.219 163.346 171.412 1.00 109.97 ?  171 GLN S CB  1 
ATOM   8482 C CG  . GLN E 5 184 ? 148.975 163.106 172.233 1.00 112.23 ?  171 GLN S CG  1 
ATOM   8483 C CD  . GLN E 5 184 ? 149.274 162.354 173.510 1.00 116.03 ?  171 GLN S CD  1 
ATOM   8484 O OE1 . GLN E 5 184 ? 150.165 162.730 174.269 1.00 114.63 ?  171 GLN S OE1 1 
ATOM   8485 N NE2 . GLN E 5 184 ? 148.534 161.279 173.751 1.00 113.76 ?  171 GLN S NE2 1 
ATOM   8486 N N   . SER E 5 185 ? 148.981 163.510 168.691 1.00 100.70 ?  172 SER S N   1 
ATOM   8487 C CA  . SER E 5 185 ? 148.001 163.391 167.629 1.00 95.90  ?  172 SER S CA  1 
ATOM   8488 C C   . SER E 5 185 ? 146.641 162.976 168.179 1.00 94.60  ?  172 SER S C   1 
ATOM   8489 O O   . SER E 5 185 ? 146.548 162.402 169.265 1.00 99.85  ?  172 SER S O   1 
ATOM   8490 C CB  . SER E 5 185 ? 148.471 162.371 166.598 1.00 102.34 ?  172 SER S CB  1 
ATOM   8491 O OG  . SER E 5 185 ? 149.882 162.364 166.497 1.00 109.36 ?  172 SER S OG  1 
ATOM   8492 N N   . PRO E 5 186 ? 145.569 163.263 167.445 1.00 78.54  ?  173 PRO S N   1 
ATOM   8493 C CA  . PRO E 5 186 ? 144.246 162.795 167.864 1.00 81.64  ?  173 PRO S CA  1 
ATOM   8494 C C   . PRO E 5 186 ? 144.157 161.281 167.843 1.00 86.32  ?  173 PRO S C   1 
ATOM   8495 O O   . PRO E 5 186 ? 144.825 160.604 167.058 1.00 91.89  ?  173 PRO S O   1 
ATOM   8496 C CB  . PRO E 5 186 ? 143.302 163.418 166.829 1.00 81.62  ?  173 PRO S CB  1 
ATOM   8497 C CG  . PRO E 5 186 ? 144.064 164.542 166.240 1.00 82.30  ?  173 PRO S CG  1 
ATOM   8498 C CD  . PRO E 5 186 ? 145.494 164.135 166.263 1.00 81.46  ?  173 PRO S CD  1 
ATOM   8499 N N   . GLN E 5 187 ? 143.322 160.749 168.728 1.00 92.74  ?  174 GLN S N   1 
ATOM   8500 C CA  . GLN E 5 187 ? 143.078 159.318 168.804 1.00 83.77  ?  174 GLN S CA  1 
ATOM   8501 C C   . GLN E 5 187 ? 141.582 159.062 168.730 1.00 82.10  ?  174 GLN S C   1 
ATOM   8502 O O   . GLN E 5 187 ? 140.783 159.840 169.256 1.00 83.12  ?  174 GLN S O   1 
ATOM   8503 C CB  . GLN E 5 187 ? 143.668 158.714 170.086 1.00 86.49  ?  174 GLN S CB  1 
ATOM   8504 C CG  . GLN E 5 187 ? 142.888 159.013 171.350 1.00 89.60  ?  174 GLN S CG  1 
ATOM   8505 C CD  . GLN E 5 187 ? 142.824 157.827 172.290 1.00 99.23  ?  174 GLN S CD  1 
ATOM   8506 O OE1 . GLN E 5 187 ? 142.806 157.987 173.509 1.00 97.32  ?  174 GLN S OE1 1 
ATOM   8507 N NE2 . GLN E 5 187 ? 142.798 156.627 171.726 1.00 92.82  ?  174 GLN S NE2 1 
ATOM   8508 N N   . LEU E 5 188 ? 141.208 157.977 168.062 1.00 75.87  ?  175 LEU S N   1 
ATOM   8509 C CA  . LEU E 5 188 ? 139.801 157.643 167.908 1.00 66.77  ?  175 LEU S CA  1 
ATOM   8510 C C   . LEU E 5 188 ? 139.228 157.145 169.227 1.00 74.99  ?  175 LEU S C   1 
ATOM   8511 O O   . LEU E 5 188 ? 139.807 156.273 169.879 1.00 84.29  ?  175 LEU S O   1 
ATOM   8512 C CB  . LEU E 5 188 ? 139.627 156.583 166.825 1.00 62.45  ?  175 LEU S CB  1 
ATOM   8513 C CG  . LEU E 5 188 ? 138.210 156.079 166.574 1.00 59.91  ?  175 LEU S CG  1 
ATOM   8514 C CD1 . LEU E 5 188 ? 137.403 157.131 165.861 1.00 70.88  ?  175 LEU S CD1 1 
ATOM   8515 C CD2 . LEU E 5 188 ? 138.242 154.805 165.769 1.00 64.77  ?  175 LEU S CD2 1 
ATOM   8516 N N   . LEU E 5 189 ? 138.087 157.702 169.620 1.00 75.14  ?  176 LEU S N   1 
ATOM   8517 C CA  . LEU E 5 189 ? 137.376 157.279 170.817 1.00 74.49  ?  176 LEU S CA  1 
ATOM   8518 C C   . LEU E 5 189 ? 136.137 156.461 170.495 1.00 77.94  ?  176 LEU S C   1 
ATOM   8519 O O   . LEU E 5 189 ? 135.986 155.341 170.987 1.00 92.85  ?  176 LEU S O   1 
ATOM   8520 C CB  . LEU E 5 189 ? 136.983 158.502 171.655 1.00 77.64  ?  176 LEU S CB  1 
ATOM   8521 C CG  . LEU E 5 189 ? 138.111 159.240 172.372 1.00 83.99  ?  176 LEU S CG  1 
ATOM   8522 C CD1 . LEU E 5 189 ? 137.538 160.212 173.374 1.00 83.78  ?  176 LEU S CD1 1 
ATOM   8523 C CD2 . LEU E 5 189 ? 139.043 158.265 173.055 1.00 80.79  ?  176 LEU S CD2 1 
ATOM   8524 N N   . ILE E 5 190 ? 135.245 156.995 169.671 1.00 73.68  ?  177 ILE S N   1 
ATOM   8525 C CA  . ILE E 5 190 ? 134.013 156.326 169.283 1.00 74.30  ?  177 ILE S CA  1 
ATOM   8526 C C   . ILE E 5 190 ? 133.858 156.450 167.777 1.00 71.39  ?  177 ILE S C   1 
ATOM   8527 O O   . ILE E 5 190 ? 134.038 157.537 167.221 1.00 87.78  ?  177 ILE S O   1 
ATOM   8528 C CB  . ILE E 5 190 ? 132.793 156.924 170.009 1.00 81.37  ?  177 ILE S CB  1 
ATOM   8529 C CG1 . ILE E 5 190 ? 132.783 156.485 171.470 1.00 82.48  ?  177 ILE S CG1 1 
ATOM   8530 C CG2 . ILE E 5 190 ? 131.502 156.541 169.319 1.00 80.39  ?  177 ILE S CG2 1 
ATOM   8531 C CD1 . ILE E 5 190 ? 132.618 157.614 172.426 1.00 84.10  ?  177 ILE S CD1 1 
ATOM   8532 N N   . TYR E 5 191 ? 133.539 155.343 167.118 1.00 69.28  ?  178 TYR S N   1 
ATOM   8533 C CA  . TYR E 5 191 ? 133.264 155.345 165.692 1.00 75.84  ?  178 TYR S CA  1 
ATOM   8534 C C   . TYR E 5 191 ? 131.808 154.978 165.450 1.00 76.70  ?  178 TYR S C   1 
ATOM   8535 O O   . TYR E 5 191 ? 131.268 154.083 166.103 1.00 87.52  ?  178 TYR S O   1 
ATOM   8536 C CB  . TYR E 5 191 ? 134.194 154.391 164.935 1.00 82.46  ?  178 TYR S CB  1 
ATOM   8537 C CG  . TYR E 5 191 ? 134.234 152.969 165.433 1.00 74.20  ?  178 TYR S CG  1 
ATOM   8538 C CD1 . TYR E 5 191 ? 135.002 152.617 166.528 1.00 74.46  ?  178 TYR S CD1 1 
ATOM   8539 C CD2 . TYR E 5 191 ? 133.531 151.971 164.784 1.00 74.87  ?  178 TYR S CD2 1 
ATOM   8540 C CE1 . TYR E 5 191 ? 135.049 151.319 166.975 1.00 72.70  ?  178 TYR S CE1 1 
ATOM   8541 C CE2 . TYR E 5 191 ? 133.573 150.672 165.223 1.00 76.89  ?  178 TYR S CE2 1 
ATOM   8542 C CZ  . TYR E 5 191 ? 134.333 150.351 166.318 1.00 75.98  ?  178 TYR S CZ  1 
ATOM   8543 O OH  . TYR E 5 191 ? 134.375 149.051 166.758 1.00 82.96  ?  178 TYR S OH  1 
ATOM   8544 N N   . ARG E 5 192 ? 131.176 155.698 164.524 1.00 77.92  ?  179 ARG S N   1 
ATOM   8545 C CA  . ARG E 5 192 ? 129.761 155.534 164.192 1.00 79.60  ?  179 ARG S CA  1 
ATOM   8546 C C   . ARG E 5 192 ? 128.858 155.770 165.402 1.00 82.56  ?  179 ARG S C   1 
ATOM   8547 O O   . ARG E 5 192 ? 127.800 155.153 165.534 1.00 78.53  ?  179 ARG S O   1 
ATOM   8548 C CB  . ARG E 5 192 ? 129.494 154.168 163.558 1.00 77.58  ?  179 ARG S CB  1 
ATOM   8549 C CG  . ARG E 5 192 ? 129.715 154.168 162.057 1.00 70.05  ?  179 ARG S CG  1 
ATOM   8550 C CD  . ARG E 5 192 ? 129.608 152.783 161.463 1.00 76.14  ?  179 ARG S CD  1 
ATOM   8551 N NE  . ARG E 5 192 ? 130.438 151.819 162.173 1.00 86.15  ?  179 ARG S NE  1 
ATOM   8552 C CZ  . ARG E 5 192 ? 131.450 151.160 161.630 1.00 81.82  ?  179 ARG S CZ  1 
ATOM   8553 N NH1 . ARG E 5 192 ? 131.801 151.349 160.371 1.00 81.19  1  179 ARG S NH1 1 
ATOM   8554 N NH2 . ARG E 5 192 ? 132.127 150.290 162.370 1.00 80.67  ?  179 ARG S NH2 1 
ATOM   8555 N N   . MET E 5 193 ? 129.307 156.645 166.303 1.00 98.87  ?  180 MET S N   1 
ATOM   8556 C CA  . MET E 5 193 ? 128.499 157.311 167.322 1.00 96.62  ?  180 MET S CA  1 
ATOM   8557 C C   . MET E 5 193 ? 128.098 156.392 168.472 1.00 98.55  ?  180 MET S C   1 
ATOM   8558 O O   . MET E 5 193 ? 127.674 156.867 169.529 1.00 103.24 ?  180 MET S O   1 
ATOM   8559 C CB  . MET E 5 193 ? 127.265 157.935 166.651 1.00 93.17  ?  180 MET S CB  1 
ATOM   8560 C CG  . MET E 5 193 ? 126.100 158.314 167.554 1.00 96.87  ?  180 MET S CG  1 
ATOM   8561 S SD  . MET E 5 193 ? 124.500 157.831 166.886 1.00 117.92 ?  180 MET S SD  1 
ATOM   8562 C CE  . MET E 5 193 ? 124.226 156.282 167.731 1.00 96.53  ?  180 MET S CE  1 
ATOM   8563 N N   . SER E 5 194 ? 128.303 155.088 168.324 1.00 96.13  ?  181 SER S N   1 
ATOM   8564 C CA  . SER E 5 194 ? 127.992 154.151 169.397 1.00 90.32  ?  181 SER S CA  1 
ATOM   8565 C C   . SER E 5 194 ? 129.187 153.313 169.812 1.00 92.70  ?  181 SER S C   1 
ATOM   8566 O O   . SER E 5 194 ? 129.477 153.203 171.008 1.00 91.32  ?  181 SER S O   1 
ATOM   8567 C CB  . SER E 5 194 ? 126.833 153.234 168.979 1.00 91.18  ?  181 SER S CB  1 
ATOM   8568 O OG  . SER E 5 194 ? 125.584 153.800 169.330 1.00 95.92  ?  181 SER S OG  1 
ATOM   8569 N N   . ASN E 5 195 ? 129.892 152.722 168.853 1.00 90.81  ?  182 ASN S N   1 
ATOM   8570 C CA  . ASN E 5 195 ? 130.907 151.727 169.162 1.00 79.57  ?  182 ASN S CA  1 
ATOM   8571 C C   . ASN E 5 195 ? 132.145 152.371 169.765 1.00 81.70  ?  182 ASN S C   1 
ATOM   8572 O O   . ASN E 5 195 ? 132.615 153.408 169.293 1.00 89.33  ?  182 ASN S O   1 
ATOM   8573 C CB  . ASN E 5 195 ? 131.269 150.948 167.903 1.00 74.01  ?  182 ASN S CB  1 
ATOM   8574 C CG  . ASN E 5 195 ? 130.117 150.857 166.930 1.00 87.73  ?  182 ASN S CG  1 
ATOM   8575 O OD1 . ASN E 5 195 ? 129.299 149.947 166.999 1.00 97.75  ?  182 ASN S OD1 1 
ATOM   8576 N ND2 . ASN E 5 195 ? 130.049 151.807 166.010 1.00 87.45  ?  182 ASN S ND2 1 
ATOM   8577 N N   . LEU E 5 196 ? 132.672 151.748 170.812 1.00 87.17  ?  183 LEU S N   1 
ATOM   8578 C CA  . LEU E 5 196 ? 133.886 152.218 171.460 1.00 85.37  ?  183 LEU S CA  1 
ATOM   8579 C C   . LEU E 5 196 ? 135.104 151.627 170.765 1.00 89.33  ?  183 LEU S C   1 
ATOM   8580 O O   . LEU E 5 196 ? 135.152 150.423 170.499 1.00 93.28  ?  183 LEU S O   1 
ATOM   8581 C CB  . LEU E 5 196 ? 133.876 151.832 172.936 1.00 86.75  ?  183 LEU S CB  1 
ATOM   8582 C CG  . LEU E 5 196 ? 134.890 152.522 173.842 1.00 90.20  ?  183 LEU S CG  1 
ATOM   8583 C CD1 . LEU E 5 196 ? 134.415 153.915 174.186 1.00 93.88  ?  183 LEU S CD1 1 
ATOM   8584 C CD2 . LEU E 5 196 ? 135.110 151.705 175.097 1.00 89.02  ?  183 LEU S CD2 1 
ATOM   8585 N N   . ALA E 5 197 ? 136.086 152.473 170.473 1.00 88.03  ?  184 ALA S N   1 
ATOM   8586 C CA  . ALA E 5 197 ? 137.273 152.016 169.772 1.00 86.03  ?  184 ALA S CA  1 
ATOM   8587 C C   . ALA E 5 197 ? 138.117 151.119 170.671 1.00 90.25  ?  184 ALA S C   1 
ATOM   8588 O O   . ALA E 5 197 ? 138.066 151.198 171.900 1.00 97.76  ?  184 ALA S O   1 
ATOM   8589 C CB  . ALA E 5 197 ? 138.102 153.204 169.289 1.00 85.32  ?  184 ALA S CB  1 
ATOM   8590 N N   . SER E 5 198 ? 138.899 150.249 170.036 1.00 98.42  ?  185 SER S N   1 
ATOM   8591 C CA  . SER E 5 198 ? 139.727 149.308 170.776 1.00 103.16 ?  185 SER S CA  1 
ATOM   8592 C C   . SER E 5 198 ? 140.815 150.047 171.542 1.00 101.05 ?  185 SER S C   1 
ATOM   8593 O O   . SER E 5 198 ? 141.495 150.918 170.993 1.00 100.68 ?  185 SER S O   1 
ATOM   8594 C CB  . SER E 5 198 ? 140.347 148.288 169.825 1.00 100.00 ?  185 SER S CB  1 
ATOM   8595 O OG  . SER E 5 198 ? 141.714 148.577 169.592 1.00 102.58 ?  185 SER S OG  1 
ATOM   8596 N N   . GLY E 5 199 ? 140.982 149.692 172.814 1.00 93.82  ?  186 GLY S N   1 
ATOM   8597 C CA  . GLY E 5 199 ? 141.924 150.351 173.684 1.00 95.05  ?  186 GLY S CA  1 
ATOM   8598 C C   . GLY E 5 199 ? 141.347 151.492 174.491 1.00 101.13 ?  186 GLY S C   1 
ATOM   8599 O O   . GLY E 5 199 ? 141.953 151.896 175.488 1.00 100.89 ?  186 GLY S O   1 
ATOM   8600 N N   . VAL E 5 200 ? 140.202 152.022 174.087 1.00 101.87 ?  187 VAL S N   1 
ATOM   8601 C CA  . VAL E 5 200 ? 139.551 153.101 174.838 1.00 97.95  ?  187 VAL S CA  1 
ATOM   8602 C C   . VAL E 5 200 ? 138.903 152.516 176.087 1.00 102.01 ?  187 VAL S C   1 
ATOM   8603 O O   . VAL E 5 200 ? 138.248 151.463 176.005 1.00 106.89 ?  187 VAL S O   1 
ATOM   8604 C CB  . VAL E 5 200 ? 138.519 153.808 173.959 1.00 93.92  ?  187 VAL S CB  1 
ATOM   8605 C CG1 . VAL E 5 200 ? 137.948 155.016 174.668 1.00 94.45  ?  187 VAL S CG1 1 
ATOM   8606 C CG2 . VAL E 5 200 ? 139.146 154.219 172.645 1.00 98.25  ?  187 VAL S CG2 1 
ATOM   8607 N N   . PRO E 5 201 ? 139.061 153.138 177.254 1.00 109.69 ?  188 PRO S N   1 
ATOM   8608 C CA  . PRO E 5 201 ? 138.377 152.638 178.450 1.00 108.39 ?  188 PRO S CA  1 
ATOM   8609 C C   . PRO E 5 201 ? 136.866 152.718 178.300 1.00 110.82 ?  188 PRO S C   1 
ATOM   8610 O O   . PRO E 5 201 ? 136.333 153.571 177.590 1.00 114.78 ?  188 PRO S O   1 
ATOM   8611 C CB  . PRO E 5 201 ? 138.880 153.563 179.563 1.00 106.54 ?  188 PRO S CB  1 
ATOM   8612 C CG  . PRO E 5 201 ? 139.408 154.766 178.859 1.00 108.72 ?  188 PRO S CG  1 
ATOM   8613 C CD  . PRO E 5 201 ? 139.945 154.273 177.559 1.00 107.17 ?  188 PRO S CD  1 
ATOM   8614 N N   . ASP E 5 202 ? 136.174 151.810 178.990 1.00 119.53 ?  189 ASP S N   1 
ATOM   8615 C CA  . ASP E 5 202 ? 134.723 151.718 178.890 1.00 120.29 ?  189 ASP S CA  1 
ATOM   8616 C C   . ASP E 5 202 ? 134.010 152.913 179.506 1.00 122.25 ?  189 ASP S C   1 
ATOM   8617 O O   . ASP E 5 202 ? 132.788 153.023 179.359 1.00 117.08 ?  189 ASP S O   1 
ATOM   8618 C CB  . ASP E 5 202 ? 134.234 150.429 179.550 1.00 121.35 ?  189 ASP S CB  1 
ATOM   8619 C CG  . ASP E 5 202 ? 134.258 150.503 181.062 1.00 126.32 ?  189 ASP S CG  1 
ATOM   8620 O OD1 . ASP E 5 202 ? 135.261 150.996 181.618 1.00 127.50 ?  189 ASP S OD1 1 
ATOM   8621 O OD2 . ASP E 5 202 ? 133.274 150.067 181.696 1.00 123.44 -1 189 ASP S OD2 1 
ATOM   8622 N N   . ARG E 5 203 ? 134.734 153.792 180.200 1.00 122.90 ?  190 ARG S N   1 
ATOM   8623 C CA  . ARG E 5 203 ? 134.118 154.990 180.760 1.00 123.41 ?  190 ARG S CA  1 
ATOM   8624 C C   . ARG E 5 203 ? 133.533 155.874 179.667 1.00 124.04 ?  190 ARG S C   1 
ATOM   8625 O O   . ARG E 5 203 ? 132.451 156.447 179.835 1.00 123.44 ?  190 ARG S O   1 
ATOM   8626 C CB  . ARG E 5 203 ? 135.145 155.761 181.583 1.00 123.00 ?  190 ARG S CB  1 
ATOM   8627 C CG  . ARG E 5 203 ? 136.321 154.913 182.026 1.00 124.47 ?  190 ARG S CG  1 
ATOM   8628 C CD  . ARG E 5 203 ? 137.262 155.707 182.901 1.00 123.56 ?  190 ARG S CD  1 
ATOM   8629 N NE  . ARG E 5 203 ? 137.480 157.040 182.359 1.00 124.37 ?  190 ARG S NE  1 
ATOM   8630 C CZ  . ARG E 5 203 ? 138.610 157.442 181.798 1.00 124.25 ?  190 ARG S CZ  1 
ATOM   8631 N NH1 . ARG E 5 203 ? 139.653 156.637 181.691 1.00 122.89 1  190 ARG S NH1 1 
ATOM   8632 N NH2 . ARG E 5 203 ? 138.696 158.685 181.336 1.00 122.87 ?  190 ARG S NH2 1 
ATOM   8633 N N   . PHE E 5 204 ? 134.238 156.006 178.546 1.00 112.01 ?  191 PHE S N   1 
ATOM   8634 C CA  . PHE E 5 204 ? 133.722 156.776 177.425 1.00 108.87 ?  191 PHE S CA  1 
ATOM   8635 C C   . PHE E 5 204 ? 132.498 156.094 176.830 1.00 107.84 ?  191 PHE S C   1 
ATOM   8636 O O   . PHE E 5 204 ? 132.466 154.873 176.663 1.00 108.34 ?  191 PHE S O   1 
ATOM   8637 C CB  . PHE E 5 204 ? 134.796 156.943 176.354 1.00 104.18 ?  191 PHE S CB  1 
ATOM   8638 C CG  . PHE E 5 204 ? 135.962 157.776 176.790 1.00 108.30 ?  191 PHE S CG  1 
ATOM   8639 C CD1 . PHE E 5 204 ? 135.939 159.149 176.647 1.00 108.80 ?  191 PHE S CD1 1 
ATOM   8640 C CD2 . PHE E 5 204 ? 137.084 157.185 177.336 1.00 109.31 ?  191 PHE S CD2 1 
ATOM   8641 C CE1 . PHE E 5 204 ? 137.011 159.914 177.043 1.00 109.43 ?  191 PHE S CE1 1 
ATOM   8642 C CE2 . PHE E 5 204 ? 138.159 157.947 177.732 1.00 108.27 ?  191 PHE S CE2 1 
ATOM   8643 C CZ  . PHE E 5 204 ? 138.122 159.312 177.586 1.00 108.87 ?  191 PHE S CZ  1 
ATOM   8644 N N   . SER E 5 205 ? 131.483 156.891 176.512 1.00 110.40 ?  192 SER S N   1 
ATOM   8645 C CA  . SER E 5 205 ? 130.252 156.368 175.941 1.00 110.34 ?  192 SER S CA  1 
ATOM   8646 C C   . SER E 5 205 ? 129.697 157.380 174.953 1.00 114.33 ?  192 SER S C   1 
ATOM   8647 O O   . SER E 5 205 ? 129.676 158.581 175.232 1.00 114.32 ?  192 SER S O   1 
ATOM   8648 C CB  . SER E 5 205 ? 129.217 156.063 177.027 1.00 109.42 ?  192 SER S CB  1 
ATOM   8649 O OG  . SER E 5 205 ? 127.899 156.251 176.545 1.00 106.38 ?  192 SER S OG  1 
ATOM   8650 N N   . GLY E 5 206 ? 129.246 156.890 173.810 1.00 107.82 ?  193 GLY S N   1 
ATOM   8651 C CA  . GLY E 5 206 ? 128.686 157.736 172.769 1.00 107.66 ?  193 GLY S CA  1 
ATOM   8652 C C   . GLY E 5 206 ? 127.216 157.432 172.563 1.00 111.25 ?  193 GLY S C   1 
ATOM   8653 O O   . GLY E 5 206 ? 126.800 156.276 172.640 1.00 112.50 ?  193 GLY S O   1 
ATOM   8654 N N   . SER E 5 207 ? 126.437 158.477 172.304 1.00 111.22 ?  194 SER S N   1 
ATOM   8655 C CA  . SER E 5 207 ? 125.004 158.329 172.098 1.00 105.49 ?  194 SER S CA  1 
ATOM   8656 C C   . SER E 5 207 ? 124.494 159.542 171.339 1.00 105.35 ?  194 SER S C   1 
ATOM   8657 O O   . SER E 5 207 ? 125.186 160.553 171.205 1.00 110.82 ?  194 SER S O   1 
ATOM   8658 C CB  . SER E 5 207 ? 124.262 158.167 173.426 1.00 107.11 ?  194 SER S CB  1 
ATOM   8659 O OG  . SER E 5 207 ? 124.353 159.347 174.202 1.00 109.07 ?  194 SER S OG  1 
ATOM   8660 N N   . GLY E 5 208 ? 123.269 159.426 170.840 1.00 101.64 ?  195 GLY S N   1 
ATOM   8661 C CA  . GLY E 5 208 ? 122.635 160.526 170.145 1.00 100.23 ?  195 GLY S CA  1 
ATOM   8662 C C   . GLY E 5 208 ? 121.811 160.081 168.958 1.00 100.05 ?  195 GLY S C   1 
ATOM   8663 O O   . GLY E 5 208 ? 121.893 158.926 168.534 1.00 102.24 ?  195 GLY S O   1 
ATOM   8664 N N   . SER E 5 209 ? 121.017 160.990 168.411 1.00 113.30 ?  196 SER S N   1 
ATOM   8665 C CA  . SER E 5 209 ? 120.199 160.731 167.236 1.00 114.52 ?  196 SER S CA  1 
ATOM   8666 C C   . SER E 5 209 ? 120.671 161.637 166.103 1.00 118.51 ?  196 SER S C   1 
ATOM   8667 O O   . SER E 5 209 ? 121.682 162.330 166.219 1.00 124.55 ?  196 SER S O   1 
ATOM   8668 C CB  . SER E 5 209 ? 118.718 160.944 167.553 1.00 116.63 ?  196 SER S CB  1 
ATOM   8669 O OG  . SER E 5 209 ? 118.342 162.290 167.326 1.00 117.45 ?  196 SER S OG  1 
ATOM   8670 N N   . GLY E 5 210 ? 119.932 161.626 164.998 1.00 115.23 ?  197 GLY S N   1 
ATOM   8671 C CA  . GLY E 5 210 ? 120.281 162.464 163.868 1.00 115.01 ?  197 GLY S CA  1 
ATOM   8672 C C   . GLY E 5 210 ? 120.360 163.934 164.225 1.00 113.13 ?  197 GLY S C   1 
ATOM   8673 O O   . GLY E 5 210 ? 119.452 164.475 164.863 1.00 114.15 ?  197 GLY S O   1 
ATOM   8674 N N   . THR E 5 211 ? 121.455 164.583 163.828 1.00 109.18 ?  198 THR S N   1 
ATOM   8675 C CA  . THR E 5 211 ? 121.708 166.005 164.060 1.00 114.70 ?  198 THR S CA  1 
ATOM   8676 C C   . THR E 5 211 ? 121.799 166.360 165.540 1.00 113.20 ?  198 THR S C   1 
ATOM   8677 O O   . THR E 5 211 ? 121.675 167.533 165.902 1.00 118.92 ?  198 THR S O   1 
ATOM   8678 C CB  . THR E 5 211 ? 120.651 166.892 163.386 1.00 116.98 ?  198 THR S CB  1 
ATOM   8679 O OG1 . THR E 5 211 ? 119.400 166.761 164.072 1.00 120.94 ?  198 THR S OG1 1 
ATOM   8680 C CG2 . THR E 5 211 ? 120.471 166.506 161.934 1.00 112.02 ?  198 THR S CG2 1 
ATOM   8681 N N   . ALA E 5 212 ? 122.016 165.381 166.415 1.00 105.92 ?  199 ALA S N   1 
ATOM   8682 C CA  . ALA E 5 212 ? 122.183 165.673 167.837 1.00 108.30 ?  199 ALA S CA  1 
ATOM   8683 C C   . ALA E 5 212 ? 122.937 164.515 168.473 1.00 113.17 ?  199 ALA S C   1 
ATOM   8684 O O   . ALA E 5 212 ? 122.367 163.435 168.651 1.00 122.11 ?  199 ALA S O   1 
ATOM   8685 C CB  . ALA E 5 212 ? 120.835 165.889 168.513 1.00 109.33 ?  199 ALA S CB  1 
ATOM   8686 N N   . PHE E 5 213 ? 124.197 164.741 168.828 1.00 99.53  ?  200 PHE S N   1 
ATOM   8687 C CA  . PHE E 5 213 ? 125.048 163.692 169.362 1.00 100.15 ?  200 PHE S CA  1 
ATOM   8688 C C   . PHE E 5 213 ? 125.754 164.189 170.611 1.00 104.59 ?  200 PHE S C   1 
ATOM   8689 O O   . PHE E 5 213 ? 126.050 165.379 170.746 1.00 109.32 ?  200 PHE S O   1 
ATOM   8690 C CB  . PHE E 5 213 ? 126.080 163.232 168.330 1.00 95.73  ?  200 PHE S CB  1 
ATOM   8691 C CG  . PHE E 5 213 ? 125.499 162.965 166.976 1.00 93.63  ?  200 PHE S CG  1 
ATOM   8692 C CD1 . PHE E 5 213 ? 125.402 163.976 166.040 1.00 99.95  ?  200 PHE S CD1 1 
ATOM   8693 C CD2 . PHE E 5 213 ? 125.049 161.707 166.640 1.00 94.86  ?  200 PHE S CD2 1 
ATOM   8694 C CE1 . PHE E 5 213 ? 124.870 163.735 164.798 1.00 105.16 ?  200 PHE S CE1 1 
ATOM   8695 C CE2 . PHE E 5 213 ? 124.515 161.461 165.398 1.00 101.36 ?  200 PHE S CE2 1 
ATOM   8696 C CZ  . PHE E 5 213 ? 124.425 162.477 164.476 1.00 104.99 ?  200 PHE S CZ  1 
ATOM   8697 N N   . THR E 5 214 ? 126.021 163.264 171.528 1.00 102.03 ?  201 THR S N   1 
ATOM   8698 C CA  . THR E 5 214 ? 126.700 163.594 172.768 1.00 105.48 ?  201 THR S CA  1 
ATOM   8699 C C   . THR E 5 214 ? 127.735 162.524 173.077 1.00 103.74 ?  201 THR S C   1 
ATOM   8700 O O   . THR E 5 214 ? 127.619 161.377 172.640 1.00 107.48 ?  201 THR S O   1 
ATOM   8701 C CB  . THR E 5 214 ? 125.709 163.742 173.936 1.00 109.73 ?  201 THR S CB  1 
ATOM   8702 O OG1 . THR E 5 214 ? 126.264 164.606 174.934 1.00 110.34 ?  201 THR S OG1 1 
ATOM   8703 C CG2 . THR E 5 214 ? 125.395 162.398 174.564 1.00 107.49 ?  201 THR S CG2 1 
ATOM   8704 N N   . LEU E 5 215 ? 128.767 162.927 173.811 1.00 107.82 ?  202 LEU S N   1 
ATOM   8705 C CA  . LEU E 5 215 ? 129.801 162.025 174.300 1.00 107.57 ?  202 LEU S CA  1 
ATOM   8706 C C   . LEU E 5 215 ? 129.940 162.258 175.794 1.00 112.62 ?  202 LEU S C   1 
ATOM   8707 O O   . LEU E 5 215 ? 130.176 163.390 176.226 1.00 117.47 ?  202 LEU S O   1 
ATOM   8708 C CB  . LEU E 5 215 ? 131.132 162.266 173.581 1.00 110.80 ?  202 LEU S CB  1 
ATOM   8709 C CG  . LEU E 5 215 ? 132.429 161.928 174.321 1.00 111.59 ?  202 LEU S CG  1 
ATOM   8710 C CD1 . LEU E 5 215 ? 132.553 160.441 174.543 1.00 110.28 ?  202 LEU S CD1 1 
ATOM   8711 C CD2 . LEU E 5 215 ? 133.635 162.453 173.570 1.00 110.16 ?  202 LEU S CD2 1 
ATOM   8712 N N   . THR E 5 216 ? 129.788 161.197 176.580 1.00 117.11 ?  203 THR S N   1 
ATOM   8713 C CA  . THR E 5 216 ? 129.808 161.288 178.032 1.00 118.46 ?  203 THR S CA  1 
ATOM   8714 C C   . THR E 5 216 ? 131.035 160.575 178.577 1.00 118.38 ?  203 THR S C   1 
ATOM   8715 O O   . THR E 5 216 ? 131.274 159.407 178.254 1.00 115.82 ?  203 THR S O   1 
ATOM   8716 C CB  . THR E 5 216 ? 128.541 160.683 178.637 1.00 121.25 ?  203 THR S CB  1 
ATOM   8717 O OG1 . THR E 5 216 ? 128.686 159.260 178.722 1.00 122.11 ?  203 THR S OG1 1 
ATOM   8718 C CG2 . THR E 5 216 ? 127.331 161.012 177.780 1.00 119.94 ?  203 THR S CG2 1 
ATOM   8719 N N   . ILE E 5 217 ? 131.807 161.276 179.405 1.00 128.03 ?  204 ILE S N   1 
ATOM   8720 C CA  . ILE E 5 217 ? 132.956 160.676 180.071 1.00 129.19 ?  204 ILE S CA  1 
ATOM   8721 C C   . ILE E 5 217 ? 132.617 160.466 181.539 1.00 131.55 ?  204 ILE S C   1 
ATOM   8722 O O   . ILE E 5 217 ? 132.817 161.359 182.368 1.00 131.68 ?  204 ILE S O   1 
ATOM   8723 C CB  . ILE E 5 217 ? 134.218 161.544 179.920 1.00 128.57 ?  204 ILE S CB  1 
ATOM   8724 C CG1 . ILE E 5 217 ? 134.459 161.893 178.453 1.00 127.45 ?  204 ILE S CG1 1 
ATOM   8725 C CG2 . ILE E 5 217 ? 135.421 160.831 180.500 1.00 128.86 ?  204 ILE S CG2 1 
ATOM   8726 C CD1 . ILE E 5 217 ? 134.277 163.355 178.138 1.00 127.29 ?  204 ILE S CD1 1 
ATOM   8727 N N   . SER E 5 218 ? 132.101 159.286 181.869 1.00 140.48 ?  205 SER S N   1 
ATOM   8728 C CA  . SER E 5 218 ? 131.777 158.977 183.253 1.00 138.93 ?  205 SER S CA  1 
ATOM   8729 C C   . SER E 5 218 ? 133.050 158.742 184.053 1.00 140.95 ?  205 SER S C   1 
ATOM   8730 O O   . SER E 5 218 ? 133.994 158.108 183.575 1.00 142.00 ?  205 SER S O   1 
ATOM   8731 C CB  . SER E 5 218 ? 130.872 157.749 183.326 1.00 137.03 ?  205 SER S CB  1 
ATOM   8732 O OG  . SER E 5 218 ? 129.633 157.996 182.684 1.00 136.31 ?  205 SER S OG  1 
ATOM   8733 N N   . ARG E 5 219 ? 133.068 159.259 185.282 1.00 146.73 ?  206 ARG S N   1 
ATOM   8734 C CA  . ARG E 5 219 ? 134.220 159.154 186.176 1.00 147.69 ?  206 ARG S CA  1 
ATOM   8735 C C   . ARG E 5 219 ? 135.476 159.715 185.503 1.00 147.50 ?  206 ARG S C   1 
ATOM   8736 O O   . ARG E 5 219 ? 136.496 159.042 185.353 1.00 149.64 ?  206 ARG S O   1 
ATOM   8737 C CB  . ARG E 5 219 ? 134.422 157.704 186.636 1.00 146.82 ?  206 ARG S CB  1 
ATOM   8738 C CG  . ARG E 5 219 ? 135.377 157.528 187.810 1.00 145.53 ?  206 ARG S CG  1 
ATOM   8739 C CD  . ARG E 5 219 ? 135.172 158.598 188.868 1.00 147.96 ?  206 ARG S CD  1 
ATOM   8740 N NE  . ARG E 5 219 ? 133.839 158.547 189.456 1.00 152.88 ?  206 ARG S NE  1 
ATOM   8741 C CZ  . ARG E 5 219 ? 133.518 157.828 190.523 1.00 151.54 ?  206 ARG S CZ  1 
ATOM   8742 N NH1 . ARG E 5 219 ? 134.413 157.078 191.144 1.00 149.39 1  206 ARG S NH1 1 
ATOM   8743 N NH2 . ARG E 5 219 ? 132.270 157.863 190.978 1.00 148.37 ?  206 ARG S NH2 1 
ATOM   8744 N N   . LEU E 5 220 ? 135.371 160.972 185.085 1.00 143.12 ?  207 LEU S N   1 
ATOM   8745 C CA  . LEU E 5 220 ? 136.477 161.640 184.416 1.00 144.28 ?  207 LEU S CA  1 
ATOM   8746 C C   . LEU E 5 220 ? 137.628 161.876 185.386 1.00 148.16 ?  207 LEU S C   1 
ATOM   8747 O O   . LEU E 5 220 ? 137.426 162.114 186.578 1.00 151.34 ?  207 LEU S O   1 
ATOM   8748 C CB  . LEU E 5 220 ? 136.009 162.966 183.816 1.00 145.47 ?  207 LEU S CB  1 
ATOM   8749 C CG  . LEU E 5 220 ? 137.077 163.915 183.273 1.00 146.43 ?  207 LEU S CG  1 
ATOM   8750 C CD1 . LEU E 5 220 ? 136.700 164.415 181.894 1.00 146.74 ?  207 LEU S CD1 1 
ATOM   8751 C CD2 . LEU E 5 220 ? 137.286 165.079 184.225 1.00 145.22 ?  207 LEU S CD2 1 
ATOM   8752 N N   . GLU E 5 221 ? 138.846 161.800 184.865 1.00 146.53 ?  208 GLU S N   1 
ATOM   8753 C CA  . GLU E 5 221 ? 140.042 161.991 185.675 1.00 148.11 ?  208 GLU S CA  1 
ATOM   8754 C C   . GLU E 5 221 ? 141.126 162.589 184.785 1.00 147.83 ?  208 GLU S C   1 
ATOM   8755 O O   . GLU E 5 221 ? 140.836 163.133 183.715 1.00 144.67 ?  208 GLU S O   1 
ATOM   8756 C CB  . GLU E 5 221 ? 140.465 160.663 186.327 1.00 146.03 ?  208 GLU S CB  1 
ATOM   8757 C CG  . GLU E 5 221 ? 140.889 159.596 185.335 1.00 144.95 ?  208 GLU S CG  1 
ATOM   8758 C CD  . GLU E 5 221 ? 139.711 158.848 184.760 1.00 147.05 ?  208 GLU S CD  1 
ATOM   8759 O OE1 . GLU E 5 221 ? 138.961 159.452 183.966 1.00 145.54 ?  208 GLU S OE1 1 
ATOM   8760 O OE2 . GLU E 5 221 ? 139.531 157.662 185.103 1.00 149.26 -1 208 GLU S OE2 1 
ATOM   8761 N N   . ALA E 5 222 ? 142.376 162.492 185.228 1.00 152.46 ?  209 ALA S N   1 
ATOM   8762 C CA  . ALA E 5 222 ? 143.508 162.981 184.461 1.00 150.88 ?  209 ALA S CA  1 
ATOM   8763 C C   . ALA E 5 222 ? 143.683 162.161 183.187 1.00 151.77 ?  209 ALA S C   1 
ATOM   8764 O O   . ALA E 5 222 ? 142.909 161.245 182.897 1.00 150.57 ?  209 ALA S O   1 
ATOM   8765 C CB  . ALA E 5 222 ? 144.786 162.938 185.298 1.00 150.01 ?  209 ALA S CB  1 
ATOM   8766 N N   . GLU E 5 223 ? 144.720 162.513 182.419 1.00 145.94 ?  210 GLU S N   1 
ATOM   8767 C CA  . GLU E 5 223 ? 144.957 162.001 181.065 1.00 146.04 ?  210 GLU S CA  1 
ATOM   8768 C C   . GLU E 5 223 ? 143.673 161.948 180.239 1.00 146.34 ?  210 GLU S C   1 
ATOM   8769 O O   . GLU E 5 223 ? 143.499 161.070 179.392 1.00 145.82 ?  210 GLU S O   1 
ATOM   8770 C CB  . GLU E 5 223 ? 145.675 160.638 181.050 1.00 145.93 ?  210 GLU S CB  1 
ATOM   8771 C CG  . GLU E 5 223 ? 144.934 159.414 181.594 1.00 147.53 ?  210 GLU S CG  1 
ATOM   8772 C CD  . GLU E 5 223 ? 145.250 159.107 183.052 1.00 148.28 ?  210 GLU S CD  1 
ATOM   8773 O OE1 . GLU E 5 223 ? 145.357 160.038 183.873 1.00 147.20 ?  210 GLU S OE1 1 
ATOM   8774 O OE2 . GLU E 5 223 ? 145.389 157.910 183.378 1.00 146.72 -1 210 GLU S OE2 1 
ATOM   8775 N N   . ASP E 5 224 ? 142.773 162.901 180.481 1.00 133.91 ?  211 ASP S N   1 
ATOM   8776 C CA  . ASP E 5 224 ? 141.565 163.067 179.694 1.00 130.80 ?  211 ASP S CA  1 
ATOM   8777 C C   . ASP E 5 224 ? 141.377 164.488 179.196 1.00 129.08 ?  211 ASP S C   1 
ATOM   8778 O O   . ASP E 5 224 ? 140.494 164.718 178.364 1.00 128.72 ?  211 ASP S O   1 
ATOM   8779 C CB  . ASP E 5 224 ? 140.329 162.665 180.509 1.00 131.09 ?  211 ASP S CB  1 
ATOM   8780 C CG  . ASP E 5 224 ? 139.883 161.256 180.224 1.00 135.41 ?  211 ASP S CG  1 
ATOM   8781 O OD1 . ASP E 5 224 ? 140.755 160.369 180.114 1.00 135.88 ?  211 ASP S OD1 1 
ATOM   8782 O OD2 . ASP E 5 224 ? 138.661 161.031 180.110 1.00 137.64 -1 211 ASP S OD2 1 
ATOM   8783 N N   . VAL E 5 225 ? 142.164 165.445 179.685 1.00 125.71 ?  212 VAL S N   1 
ATOM   8784 C CA  . VAL E 5 225 ? 142.044 166.818 179.229 1.00 127.35 ?  212 VAL S CA  1 
ATOM   8785 C C   . VAL E 5 225 ? 142.568 166.931 177.804 1.00 125.24 ?  212 VAL S C   1 
ATOM   8786 O O   . VAL E 5 225 ? 143.478 166.203 177.385 1.00 124.83 ?  212 VAL S O   1 
ATOM   8787 C CB  . VAL E 5 225 ? 142.787 167.773 180.180 1.00 126.85 ?  212 VAL S CB  1 
ATOM   8788 C CG1 . VAL E 5 225 ? 142.285 167.589 181.599 1.00 125.13 ?  212 VAL S CG1 1 
ATOM   8789 C CG2 . VAL E 5 225 ? 144.285 167.539 180.113 1.00 122.92 ?  212 VAL S CG2 1 
ATOM   8790 N N   . GLY E 5 226 ? 141.977 167.845 177.046 1.00 113.08 ?  213 GLY S N   1 
ATOM   8791 C CA  . GLY E 5 226 ? 142.326 168.016 175.655 1.00 110.97 ?  213 GLY S CA  1 
ATOM   8792 C C   . GLY E 5 226 ? 141.110 168.368 174.831 1.00 112.39 ?  213 GLY S C   1 
ATOM   8793 O O   . GLY E 5 226 ? 140.009 168.504 175.369 1.00 115.63 ?  213 GLY S O   1 
ATOM   8794 N N   . VAL E 5 227 ? 141.287 168.504 173.537 1.00 99.66  ?  214 VAL S N   1 
ATOM   8795 C CA  . VAL E 5 227 ? 140.201 168.894 172.650 1.00 99.43  ?  214 VAL S CA  1 
ATOM   8796 C C   . VAL E 5 227 ? 139.522 167.643 172.119 1.00 101.46 ?  214 VAL S C   1 
ATOM   8797 O O   . VAL E 5 227 ? 140.182 166.671 171.740 1.00 107.03 ?  214 VAL S O   1 
ATOM   8798 C CB  . VAL E 5 227 ? 140.724 169.778 171.505 1.00 97.97  ?  214 VAL S CB  1 
ATOM   8799 C CG1 . VAL E 5 227 ? 139.584 170.542 170.879 1.00 98.79  ?  214 VAL S CG1 1 
ATOM   8800 C CG2 . VAL E 5 227 ? 141.781 170.731 172.024 1.00 100.20 ?  214 VAL S CG2 1 
ATOM   8801 N N   . TYR E 5 228 ? 138.194 167.660 172.110 1.00 95.29  ?  215 TYR S N   1 
ATOM   8802 C CA  . TYR E 5 228 ? 137.388 166.567 171.587 1.00 91.80  ?  215 TYR S CA  1 
ATOM   8803 C C   . TYR E 5 228 ? 136.711 167.042 170.312 1.00 94.11  ?  215 TYR S C   1 
ATOM   8804 O O   . TYR E 5 228 ? 136.010 168.058 170.321 1.00 102.98 ?  215 TYR S O   1 
ATOM   8805 C CB  . TYR E 5 228 ? 136.354 166.108 172.615 1.00 93.03  ?  215 TYR S CB  1 
ATOM   8806 C CG  . TYR E 5 228 ? 136.950 165.400 173.809 1.00 96.49  ?  215 TYR S CG  1 
ATOM   8807 C CD1 . TYR E 5 228 ? 137.576 166.111 174.821 1.00 97.77  ?  215 TYR S CD1 1 
ATOM   8808 C CD2 . TYR E 5 228 ? 136.889 164.022 173.924 1.00 97.31  ?  215 TYR S CD2 1 
ATOM   8809 C CE1 . TYR E 5 228 ? 138.123 165.471 175.909 1.00 98.59  ?  215 TYR S CE1 1 
ATOM   8810 C CE2 . TYR E 5 228 ? 137.434 163.373 175.010 1.00 101.03 ?  215 TYR S CE2 1 
ATOM   8811 C CZ  . TYR E 5 228 ? 138.050 164.103 175.998 1.00 101.56 ?  215 TYR S CZ  1 
ATOM   8812 O OH  . TYR E 5 228 ? 138.594 163.461 177.084 1.00 103.50 ?  215 TYR S OH  1 
ATOM   8813 N N   . TYR E 5 229 ? 136.920 166.313 169.222 1.00 79.42  ?  216 TYR S N   1 
ATOM   8814 C CA  . TYR E 5 229 ? 136.384 166.674 167.918 1.00 80.02  ?  216 TYR S CA  1 
ATOM   8815 C C   . TYR E 5 229 ? 135.345 165.651 167.493 1.00 78.68  ?  216 TYR S C   1 
ATOM   8816 O O   . TYR E 5 229 ? 135.595 164.445 167.559 1.00 90.40  ?  216 TYR S O   1 
ATOM   8817 C CB  . TYR E 5 229 ? 137.494 166.749 166.869 1.00 85.32  ?  216 TYR S CB  1 
ATOM   8818 C CG  . TYR E 5 229 ? 138.548 167.790 167.149 1.00 88.51  ?  216 TYR S CG  1 
ATOM   8819 C CD1 . TYR E 5 229 ? 138.382 169.100 166.734 1.00 84.88  ?  216 TYR S CD1 1 
ATOM   8820 C CD2 . TYR E 5 229 ? 139.710 167.462 167.824 1.00 87.63  ?  216 TYR S CD2 1 
ATOM   8821 C CE1 . TYR E 5 229 ? 139.341 170.051 166.986 1.00 87.67  ?  216 TYR S CE1 1 
ATOM   8822 C CE2 . TYR E 5 229 ? 140.673 168.408 168.080 1.00 87.86  ?  216 TYR S CE2 1 
ATOM   8823 C CZ  . TYR E 5 229 ? 140.484 169.700 167.659 1.00 89.53  ?  216 TYR S CZ  1 
ATOM   8824 O OH  . TYR E 5 229 ? 141.444 170.648 167.913 1.00 89.99  ?  216 TYR S OH  1 
ATOM   8825 N N   . CYS E 5 230 ? 134.186 166.129 167.058 1.00 90.33  ?  217 CYS S N   1 
ATOM   8826 C CA  . CYS E 5 230 ? 133.174 165.277 166.454 1.00 91.27  ?  217 CYS S CA  1 
ATOM   8827 C C   . CYS E 5 230 ? 133.278 165.401 164.942 1.00 97.18  ?  217 CYS S C   1 
ATOM   8828 O O   . CYS E 5 230 ? 133.323 166.511 164.407 1.00 109.93 ?  217 CYS S O   1 
ATOM   8829 C CB  . CYS E 5 230 ? 131.768 165.643 166.938 1.00 94.72  ?  217 CYS S CB  1 
ATOM   8830 S SG  . CYS E 5 230 ? 131.163 167.286 166.500 1.00 118.90 ?  217 CYS S SG  1 
ATOM   8831 N N   . MET E 5 231 ? 133.327 164.264 164.261 1.00 75.51  ?  218 MET S N   1 
ATOM   8832 C CA  . MET E 5 231 ? 133.591 164.228 162.835 1.00 71.49  ?  218 MET S CA  1 
ATOM   8833 C C   . MET E 5 231 ? 132.499 163.447 162.124 1.00 71.43  ?  218 MET S C   1 
ATOM   8834 O O   . MET E 5 231 ? 131.971 162.468 162.651 1.00 82.65  ?  218 MET S O   1 
ATOM   8835 C CB  . MET E 5 231 ? 134.953 163.601 162.554 1.00 79.79  ?  218 MET S CB  1 
ATOM   8836 C CG  . MET E 5 231 ? 135.301 163.487 161.096 1.00 80.20  ?  218 MET S CG  1 
ATOM   8837 S SD  . MET E 5 231 ? 136.105 161.929 160.721 1.00 90.90  ?  218 MET S SD  1 
ATOM   8838 C CE  . MET E 5 231 ? 136.975 162.410 159.252 1.00 80.25  ?  218 MET S CE  1 
ATOM   8839 N N   . GLN E 5 232 ? 132.166 163.894 160.921 1.00 75.30  ?  219 GLN S N   1 
ATOM   8840 C CA  . GLN E 5 232 ? 131.166 163.253 160.083 1.00 79.10  ?  219 GLN S CA  1 
ATOM   8841 C C   . GLN E 5 232 ? 131.843 162.445 158.986 1.00 84.95  ?  219 GLN S C   1 
ATOM   8842 O O   . GLN E 5 232 ? 132.782 162.918 158.343 1.00 99.16  ?  219 GLN S O   1 
ATOM   8843 C CB  . GLN E 5 232 ? 130.230 164.300 159.475 1.00 74.48  ?  219 GLN S CB  1 
ATOM   8844 C CG  . GLN E 5 232 ? 129.622 163.923 158.140 1.00 82.55  ?  219 GLN S CG  1 
ATOM   8845 C CD  . GLN E 5 232 ? 130.422 164.455 156.974 1.00 87.86  ?  219 GLN S CD  1 
ATOM   8846 O OE1 . GLN E 5 232 ? 131.183 165.407 157.117 1.00 83.46  ?  219 GLN S OE1 1 
ATOM   8847 N NE2 . GLN E 5 232 ? 130.263 163.838 155.813 1.00 89.45  ?  219 GLN S NE2 1 
ATOM   8848 N N   . HIS E 5 233 ? 131.368 161.218 158.780 1.00 72.26  ?  220 HIS S N   1 
ATOM   8849 C CA  . HIS E 5 233 ? 131.846 160.374 157.693 1.00 67.45  ?  220 HIS S CA  1 
ATOM   8850 C C   . HIS E 5 233 ? 130.712 159.940 156.774 1.00 79.48  ?  220 HIS S C   1 
ATOM   8851 O O   . HIS E 5 233 ? 130.830 158.920 156.091 1.00 91.75  ?  220 HIS S O   1 
ATOM   8852 C CB  . HIS E 5 233 ? 132.580 159.151 158.242 1.00 74.10  ?  220 HIS S CB  1 
ATOM   8853 C CG  . HIS E 5 233 ? 133.617 158.599 157.315 1.00 85.78  ?  220 HIS S CG  1 
ATOM   8854 N ND1 . HIS E 5 233 ? 133.329 158.199 156.029 1.00 81.51  ?  220 HIS S ND1 1 
ATOM   8855 C CD2 . HIS E 5 233 ? 134.940 158.376 157.489 1.00 82.66  ?  220 HIS S CD2 1 
ATOM   8856 C CE1 . HIS E 5 233 ? 134.430 157.755 155.450 1.00 67.18  ?  220 HIS S CE1 1 
ATOM   8857 N NE2 . HIS E 5 233 ? 135.422 157.852 156.315 1.00 70.61  ?  220 HIS S NE2 1 
ATOM   8858 N N   . LEU E 5 234 ? 129.611 160.692 156.749 1.00 84.55  ?  221 LEU S N   1 
ATOM   8859 C CA  . LEU E 5 234 ? 128.478 160.325 155.905 1.00 82.77  ?  221 LEU S CA  1 
ATOM   8860 C C   . LEU E 5 234 ? 128.857 160.364 154.432 1.00 82.61  ?  221 LEU S C   1 
ATOM   8861 O O   . LEU E 5 234 ? 128.583 159.421 153.682 1.00 93.56  ?  221 LEU S O   1 
ATOM   8862 C CB  . LEU E 5 234 ? 127.299 161.254 156.183 1.00 85.36  ?  221 LEU S CB  1 
ATOM   8863 C CG  . LEU E 5 234 ? 125.971 160.836 155.558 1.00 85.87  ?  221 LEU S CG  1 
ATOM   8864 C CD1 . LEU E 5 234 ? 125.671 159.390 155.878 1.00 78.31  ?  221 LEU S CD1 1 
ATOM   8865 C CD2 . LEU E 5 234 ? 124.856 161.735 156.042 1.00 89.27  ?  221 LEU S CD2 1 
ATOM   8866 N N   . GLU E 5 235 ? 129.482 161.454 153.997 1.00 82.18  ?  222 GLU S N   1 
ATOM   8867 C CA  . GLU E 5 235 ? 130.022 161.544 152.649 1.00 89.35  ?  222 GLU S CA  1 
ATOM   8868 C C   . GLU E 5 235 ? 131.045 162.666 152.614 1.00 90.77  ?  222 GLU S C   1 
ATOM   8869 O O   . GLU E 5 235 ? 131.090 163.518 153.503 1.00 87.78  ?  222 GLU S O   1 
ATOM   8870 C CB  . GLU E 5 235 ? 128.923 161.768 151.605 1.00 93.90  ?  222 GLU S CB  1 
ATOM   8871 C CG  . GLU E 5 235 ? 128.456 163.208 151.432 1.00 99.33  ?  222 GLU S CG  1 
ATOM   8872 C CD  . GLU E 5 235 ? 127.715 163.758 152.635 1.00 103.13 ?  222 GLU S CD  1 
ATOM   8873 O OE1 . GLU E 5 235 ? 128.218 163.638 153.770 1.00 102.33 ?  222 GLU S OE1 1 
ATOM   8874 O OE2 . GLU E 5 235 ? 126.612 164.309 152.441 1.00 100.09 -1 222 GLU S OE2 1 
ATOM   8875 N N   . TYR E 5 236 ? 131.867 162.646 151.579 1.00 82.43  ?  223 TYR S N   1 
ATOM   8876 C CA  . TYR E 5 236 ? 132.968 163.582 151.444 1.00 71.40  ?  223 TYR S CA  1 
ATOM   8877 C C   . TYR E 5 236 ? 132.474 164.940 150.951 1.00 80.61  ?  223 TYR S C   1 
ATOM   8878 O O   . TYR E 5 236 ? 131.492 165.019 150.209 1.00 90.20  ?  223 TYR S O   1 
ATOM   8879 C CB  . TYR E 5 236 ? 134.013 163.024 150.488 1.00 73.75  ?  223 TYR S CB  1 
ATOM   8880 C CG  . TYR E 5 236 ? 134.624 161.735 150.980 1.00 77.07  ?  223 TYR S CG  1 
ATOM   8881 C CD1 . TYR E 5 236 ? 134.026 160.517 150.707 1.00 76.28  ?  223 TYR S CD1 1 
ATOM   8882 C CD2 . TYR E 5 236 ? 135.792 161.738 151.724 1.00 78.82  ?  223 TYR S CD2 1 
ATOM   8883 C CE1 . TYR E 5 236 ? 134.573 159.343 151.157 1.00 79.91  ?  223 TYR S CE1 1 
ATOM   8884 C CE2 . TYR E 5 236 ? 136.346 160.565 152.177 1.00 76.06  ?  223 TYR S CE2 1 
ATOM   8885 C CZ  . TYR E 5 236 ? 135.734 159.371 151.890 1.00 84.54  ?  223 TYR S CZ  1 
ATOM   8886 O OH  . TYR E 5 236 ? 136.277 158.194 152.339 1.00 88.06  ?  223 TYR S OH  1 
ATOM   8887 N N   . PRO E 5 237 ? 133.139 166.031 151.349 1.00 81.34  ?  224 PRO S N   1 
ATOM   8888 C CA  . PRO E 5 237 ? 134.335 166.105 152.195 1.00 82.05  ?  224 PRO S CA  1 
ATOM   8889 C C   . PRO E 5 237 ? 134.030 165.840 153.660 1.00 85.48  ?  224 PRO S C   1 
ATOM   8890 O O   . PRO E 5 237 ? 132.983 166.232 154.161 1.00 89.97  ?  224 PRO S O   1 
ATOM   8891 C CB  . PRO E 5 237 ? 134.818 167.539 151.965 1.00 81.00  ?  224 PRO S CB  1 
ATOM   8892 C CG  . PRO E 5 237 ? 133.559 168.305 151.749 1.00 78.99  ?  224 PRO S CG  1 
ATOM   8893 C CD  . PRO E 5 237 ? 132.656 167.372 150.980 1.00 83.10  ?  224 PRO S CD  1 
ATOM   8894 N N   . LEU E 5 238 ? 134.930 165.170 154.371 1.00 75.06  ?  225 LEU S N   1 
ATOM   8895 C CA  . LEU E 5 238 ? 134.715 164.907 155.784 1.00 69.69  ?  225 LEU S CA  1 
ATOM   8896 C C   . LEU E 5 238 ? 134.936 166.180 156.585 1.00 71.93  ?  225 LEU S C   1 
ATOM   8897 O O   . LEU E 5 238 ? 135.937 166.876 156.400 1.00 78.23  ?  225 LEU S O   1 
ATOM   8898 C CB  . LEU E 5 238 ? 135.647 163.800 156.263 1.00 59.27  ?  225 LEU S CB  1 
ATOM   8899 C CG  . LEU E 5 238 ? 135.774 162.608 155.319 1.00 63.56  ?  225 LEU S CG  1 
ATOM   8900 C CD1 . LEU E 5 238 ? 136.945 161.744 155.713 1.00 65.03  ?  225 LEU S CD1 1 
ATOM   8901 C CD2 . LEU E 5 238 ? 134.500 161.802 155.313 1.00 70.39  ?  225 LEU S CD2 1 
ATOM   8902 N N   . THR E 5 239 ? 133.997 166.489 157.470 1.00 72.57  ?  226 THR S N   1 
ATOM   8903 C CA  . THR E 5 239 ? 133.995 167.745 158.199 1.00 77.52  ?  226 THR S CA  1 
ATOM   8904 C C   . THR E 5 239 ? 134.095 167.482 159.692 1.00 80.29  ?  226 THR S C   1 
ATOM   8905 O O   . THR E 5 239 ? 133.412 166.604 160.225 1.00 87.12  ?  226 THR S O   1 
ATOM   8906 C CB  . THR E 5 239 ? 132.733 168.551 157.903 1.00 85.01  ?  226 THR S CB  1 
ATOM   8907 O OG1 . THR E 5 239 ? 132.447 168.489 156.502 1.00 84.66  ?  226 THR S OG1 1 
ATOM   8908 C CG2 . THR E 5 239 ? 132.929 170.000 158.303 1.00 85.82  ?  226 THR S CG2 1 
ATOM   8909 N N   . PHE E 5 240 ? 134.948 168.247 160.360 1.00 73.97  ?  227 PHE S N   1 
ATOM   8910 C CA  . PHE E 5 240 ? 135.136 168.155 161.797 1.00 70.50  ?  227 PHE S CA  1 
ATOM   8911 C C   . PHE E 5 240 ? 134.385 169.276 162.500 1.00 79.42  ?  227 PHE S C   1 
ATOM   8912 O O   . PHE E 5 240 ? 134.014 170.284 161.897 1.00 86.20  ?  227 PHE S O   1 
ATOM   8913 C CB  . PHE E 5 240 ? 136.620 168.230 162.159 1.00 70.02  ?  227 PHE S CB  1 
ATOM   8914 C CG  . PHE E 5 240 ? 137.413 167.035 161.731 1.00 73.78  ?  227 PHE S CG  1 
ATOM   8915 C CD1 . PHE E 5 240 ? 137.836 166.901 160.426 1.00 74.44  ?  227 PHE S CD1 1 
ATOM   8916 C CD2 . PHE E 5 240 ? 137.746 166.051 162.638 1.00 79.77  ?  227 PHE S CD2 1 
ATOM   8917 C CE1 . PHE E 5 240 ? 138.567 165.809 160.033 1.00 75.22  ?  227 PHE S CE1 1 
ATOM   8918 C CE2 . PHE E 5 240 ? 138.477 164.958 162.248 1.00 78.83  ?  227 PHE S CE2 1 
ATOM   8919 C CZ  . PHE E 5 240 ? 138.887 164.838 160.944 1.00 80.90  ?  227 PHE S CZ  1 
ATOM   8920 N N   . GLY E 5 241 ? 134.164 169.086 163.792 1.00 94.36  ?  228 GLY S N   1 
ATOM   8921 C CA  . GLY E 5 241 ? 133.636 170.149 164.612 1.00 82.30  ?  228 GLY S CA  1 
ATOM   8922 C C   . GLY E 5 241 ? 134.710 171.143 164.984 1.00 85.51  ?  228 GLY S C   1 
ATOM   8923 O O   . GLY E 5 241 ? 135.887 170.973 164.677 1.00 97.91  ?  228 GLY S O   1 
ATOM   8924 N N   . ALA E 5 242 ? 134.285 172.213 165.655 1.00 91.40  ?  229 ALA S N   1 
ATOM   8925 C CA  . ALA E 5 242 ? 135.240 173.225 166.089 1.00 91.01  ?  229 ALA S CA  1 
ATOM   8926 C C   . ALA E 5 242 ? 136.189 172.683 167.149 1.00 94.04  ?  229 ALA S C   1 
ATOM   8927 O O   . ALA E 5 242 ? 137.354 173.090 167.202 1.00 91.40  ?  229 ALA S O   1 
ATOM   8928 C CB  . ALA E 5 242 ? 134.501 174.454 166.614 1.00 91.35  ?  229 ALA S CB  1 
ATOM   8929 N N   . GLY E 5 243 ? 135.714 171.775 167.995 1.00 100.20 ?  230 GLY S N   1 
ATOM   8930 C CA  . GLY E 5 243 ? 136.536 171.212 169.046 1.00 95.60  ?  230 GLY S CA  1 
ATOM   8931 C C   . GLY E 5 243 ? 136.201 171.764 170.415 1.00 100.48 ?  230 GLY S C   1 
ATOM   8932 O O   . GLY E 5 243 ? 136.128 172.981 170.598 1.00 103.24 ?  230 GLY S O   1 
ATOM   8933 N N   . THR E 5 244 ? 135.999 170.879 171.387 1.00 108.38 ?  231 THR S N   1 
ATOM   8934 C CA  . THR E 5 244 ? 135.647 171.264 172.747 1.00 106.38 ?  231 THR S CA  1 
ATOM   8935 C C   . THR E 5 244 ? 136.839 171.007 173.656 1.00 109.40 ?  231 THR S C   1 
ATOM   8936 O O   . THR E 5 244 ? 137.281 169.863 173.795 1.00 115.09 ?  231 THR S O   1 
ATOM   8937 C CB  . THR E 5 244 ? 134.425 170.490 173.239 1.00 109.43 ?  231 THR S CB  1 
ATOM   8938 O OG1 . THR E 5 244 ? 133.256 170.953 172.555 1.00 109.77 ?  231 THR S OG1 1 
ATOM   8939 C CG2 . THR E 5 244 ? 134.242 170.687 174.732 1.00 110.94 ?  231 THR S CG2 1 
ATOM   8940 N N   . LYS E 5 245 ? 137.345 172.065 174.277 1.00 120.77 ?  232 LYS S N   1 
ATOM   8941 C CA  . LYS E 5 245 ? 138.511 171.960 175.140 1.00 120.66 ?  232 LYS S CA  1 
ATOM   8942 C C   . LYS E 5 245 ? 138.103 171.563 176.552 1.00 123.77 ?  232 LYS S C   1 
ATOM   8943 O O   . LYS E 5 245 ? 137.120 172.070 177.097 1.00 125.52 ?  232 LYS S O   1 
ATOM   8944 C CB  . LYS E 5 245 ? 139.268 173.289 175.162 1.00 121.76 ?  232 LYS S CB  1 
ATOM   8945 C CG  . LYS E 5 245 ? 140.306 173.413 176.262 1.00 124.34 ?  232 LYS S CG  1 
ATOM   8946 C CD  . LYS E 5 245 ? 141.463 172.455 176.052 1.00 126.43 ?  232 LYS S CD  1 
ATOM   8947 C CE  . LYS E 5 245 ? 142.515 173.051 175.135 1.00 126.89 ?  232 LYS S CE  1 
ATOM   8948 N NZ  . LYS E 5 245 ? 143.729 172.189 175.057 1.00 124.64 1  232 LYS S NZ  1 
ATOM   8949 N N   . LEU E 5 246 ? 138.860 170.639 177.137 1.00 128.69 ?  233 LEU S N   1 
ATOM   8950 C CA  . LEU E 5 246 ? 138.690 170.231 178.525 1.00 127.73 ?  233 LEU S CA  1 
ATOM   8951 C C   . LEU E 5 246 ? 139.966 170.571 179.279 1.00 129.58 ?  233 LEU S C   1 
ATOM   8952 O O   . LEU E 5 246 ? 141.052 170.130 178.892 1.00 132.73 ?  233 LEU S O   1 
ATOM   8953 C CB  . LEU E 5 246 ? 138.387 168.736 178.627 1.00 129.41 ?  233 LEU S CB  1 
ATOM   8954 C CG  . LEU E 5 246 ? 136.956 168.341 178.985 1.00 133.06 ?  233 LEU S CG  1 
ATOM   8955 C CD1 . LEU E 5 246 ? 135.982 168.879 177.956 1.00 129.73 ?  233 LEU S CD1 1 
ATOM   8956 C CD2 . LEU E 5 246 ? 136.841 166.834 179.091 1.00 129.92 ?  233 LEU S CD2 1 
ATOM   8957 N N   . GLU E 5 247 ? 139.838 171.360 180.345 1.00 144.35 ?  234 GLU S N   1 
ATOM   8958 C CA  . GLU E 5 247 ? 141.002 171.731 181.141 1.00 146.58 ?  234 GLU S CA  1 
ATOM   8959 C C   . GLU E 5 247 ? 140.744 171.482 182.621 1.00 146.41 ?  234 GLU S C   1 
ATOM   8960 O O   . GLU E 5 247 ? 139.746 170.851 182.984 1.00 145.24 ?  234 GLU S O   1 
ATOM   8961 C CB  . GLU E 5 247 ? 141.400 173.196 180.914 1.00 143.93 ?  234 GLU S CB  1 
ATOM   8962 C CG  . GLU E 5 247 ? 140.351 174.282 181.216 1.00 144.16 ?  234 GLU S CG  1 
ATOM   8963 C CD  . GLU E 5 247 ? 139.114 174.260 180.327 1.00 147.15 ?  234 GLU S CD  1 
ATOM   8964 O OE1 . GLU E 5 247 ? 138.627 175.357 179.984 1.00 148.34 ?  234 GLU S OE1 1 
ATOM   8965 O OE2 . GLU E 5 247 ? 138.615 173.173 179.979 1.00 148.89 -1 234 GLU S OE2 1 
ATOM   8966 N N   . LEU E 5 248 ? 141.645 171.969 183.471 1.00 147.18 ?  235 LEU S N   1 
ATOM   8967 C CA  . LEU E 5 248 ? 141.573 171.772 184.917 1.00 146.92 ?  235 LEU S CA  1 
ATOM   8968 C C   . LEU E 5 248 ? 141.597 170.286 185.261 1.00 146.25 ?  235 LEU S C   1 
ATOM   8969 O O   . LEU E 5 248 ? 142.635 169.632 185.155 1.00 141.48 ?  235 LEU S O   1 
ATOM   8970 C CB  . LEU E 5 248 ? 140.321 172.439 185.498 1.00 147.51 ?  235 LEU S CB  1 
ATOM   8971 C CG  . LEU E 5 248 ? 140.287 172.650 187.013 1.00 146.13 ?  235 LEU S CG  1 
ATOM   8972 C CD1 . LEU E 5 248 ? 141.429 173.550 187.459 1.00 143.91 ?  235 LEU S CD1 1 
ATOM   8973 C CD2 . LEU E 5 248 ? 138.947 173.224 187.449 1.00 143.12 ?  235 LEU S CD2 1 
ATOM   8974 O OXT . LEU E 5 248 ? 140.587 169.701 185.646 1.00 146.90 -1 235 LEU S OXT 1 
HETATM 8975 C C1  . XOT F 6 .   ? 120.782 138.880 96.507  1.00 20.00  ?  401 XOT A C1  1 
HETATM 8976 C C2  . XOT F 6 .   ? 121.450 138.522 97.791  1.00 20.00  ?  401 XOT A C2  1 
HETATM 8977 C C3  . XOT F 6 .   ? 122.403 139.689 98.138  1.00 20.00  ?  401 XOT A C3  1 
HETATM 8978 C C4  . XOT F 6 .   ? 122.118 140.786 97.292  1.00 20.00  ?  401 XOT A C4  1 
HETATM 8979 C C5  . XOT F 6 .   ? 123.436 140.094 98.965  1.00 20.00  ?  401 XOT A C5  1 
HETATM 8980 C C6  . XOT F 6 .   ? 124.083 139.244 100.049 1.00 20.00  ?  401 XOT A C6  1 
HETATM 8981 C C7  . XOT F 6 .   ? 120.950 140.380 96.329  1.00 20.00  ?  401 XOT A C7  1 
HETATM 8982 C C8  . XOT F 6 .   ? 119.562 139.767 96.335  1.00 20.00  ?  401 XOT A C8  1 
HETATM 8983 N N1  . XOT F 6 .   ? 122.948 141.769 97.611  1.00 20.00  ?  401 XOT A N1  1 
HETATM 8984 N N2  . XOT F 6 .   ? 123.765 141.350 98.645  1.00 20.00  ?  401 XOT A N2  1 
HETATM 8985 O O1  . XOT F 6 .   ? 124.905 139.758 100.849 1.00 20.00  ?  401 XOT A O1  1 
HETATM 8986 O O2  . XOT F 6 .   ? 123.782 138.027 100.130 1.00 20.00  ?  401 XOT A O2  1 
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