data_9IXX
# 
_entry.id   9IXX 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9IXX         pdb_00009ixx 10.2210/pdb9ixx/pdb 
WWPDB D_1300049936 ?            ?                   
EMDB  EMD-60980    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-02 ? 
2 'EM metadata'     1 0 2025-04-02 ? 
3 'Additional map'  1 0 2025-04-02 1 
4 'Half map'        1 0 2025-04-02 1 
5 'Half map'        1 0 2025-04-02 2 
6 Image             1 0 2025-04-02 ? 
7 'Primary map'     1 0 2025-04-02 ? 
8 'Structure model' 1 1 2025-04-30 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 8 'Structure model' 'Data collection'     
2 8 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 8 'Structure model' citation        
2 8 'Structure model' citation_author 
3 8 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  8 'Structure model' '_citation.country'                 
2  8 'Structure model' '_citation.journal_abbrev'          
3  8 'Structure model' '_citation.journal_id_ASTM'         
4  8 'Structure model' '_citation.journal_id_CSD'          
5  8 'Structure model' '_citation.journal_id_ISSN'         
6  8 'Structure model' '_citation.journal_volume'          
7  8 'Structure model' '_citation.page_first'              
8  8 'Structure model' '_citation.page_last'               
9  8 'Structure model' '_citation.pdbx_database_id_DOI'    
10 8 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 8 'Structure model' '_citation.title'                   
12 8 'Structure model' '_citation.year'                    
13 8 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9IXX 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4' 
_pdbx_database_related.db_id          EMD-60980 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wcyin@simm.ac.cn 
_pdbx_contact_author.name_first         Wanchao 
_pdbx_contact_author.name_last          Yin 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6889-4907 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Jiang, M.' 1 ? 
'Xu, Y.'    2 ? 
'Yin, W.'   3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Proc.Natl.Acad.Sci.USA 
_citation.journal_id_ASTM           PNASA6 
_citation.journal_id_CSD            0040 
_citation.journal_id_ISSN           1091-6490 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            122 
_citation.language                  ? 
_citation.page_first                e2417148122 
_citation.page_last                 e2417148122 
_citation.title                     'Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1073/pnas.2417148122 
_citation.pdbx_database_id_PubMed   40193607 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Jiang, M.' 1 0009-0002-3004-8390 
primary 'Xu, Y.'    2 0000-0001-8069-7511 
primary 'Luan, X.'  3 0000-0002-1279-5432 
primary 'Wu, K.'    4 ?                   
primary 'Li, Z.'    5 ?                   
primary 'Xu, H.E.'  6 0000-0002-6829-8144 
primary 'Zhang, S.' 7 ?                   
primary 'Jiang, Y.' 8 ?                   
primary 'Yin, W.'   9 0000-0002-6889-4907 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'G-alpha q' 41724.383 1 ? ? ? ? 
2 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1' 38744.371 1 ? ? ? ? 
3 polymer     man scFv16 26408.492 1 ? ? ? ? 
4 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' 7861.143  1 ? ? ? ? 
5 polymer     man 'Cysteinyl leukotriene receptor 2' 38506.773 1 ? ? ? ? 
6 non-polymer syn 
;(5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid
;
496.660   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
4 'G gamma-I'                                                                                      
5 'CLTR2,CysLTR2,G-protein coupled receptor GPCR21,hGPCR21,G-protein coupled receptor HG57,HPN321' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGCTLSAEDKAAVERSKMIEKQLQKDKQVYRRTLRLLLLGADNSGKSTIVKQMRIYHVNGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDF
KSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASG
DGRHICYPHFTCSVDTENARRIFNDCKDIILQMNLREYNLV
;
;MGCTLSAEDKAAVERSKMIEKQLQKDKQVYRRTLRLLLLGADNSGKSTIVKQMRIYHVNGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTSGIFETKFQVDKVNFHMFDVGAQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDF
KSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASG
DGRHICYPHFTCSVDTENARRIFNDCKDIILQMNLREYNLV
;
A ? 
2 'polypeptide(L)' no no 
;MHHHHHHGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRL
LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCC
RFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDI
NAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA
GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
;MHHHHHHGSLLQSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRL
LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCC
RFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDI
NAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLA
GHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
B ? 
3 'polypeptide(L)' no no 
;MVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSAGGGGSGGGGSGGGGSADIVMTQATSSVPVTPGESVSISC
RSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTF
GAGTKLEL
;
;MVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSAGGGGSGGGGSGGGGSADIVMTQATSSVPVTPGESVSISC
RSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTF
GAGTKLEL
;
E ? 
4 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL G ? 
5 'polypeptide(L)' no no 
;MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNL
AISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCG
IIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRV
SHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLKSAL
RKGHPQKAKTKCVFPVS
;
;MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNL
AISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCG
IIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRV
SHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLKSAL
RKGHPQKAKTKCVFPVS
;
R ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        
;(5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid
;
_pdbx_entity_nonpoly.comp_id     LTD 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   CYS n 
1 4   THR n 
1 5   LEU n 
1 6   SER n 
1 7   ALA n 
1 8   GLU n 
1 9   ASP n 
1 10  LYS n 
1 11  ALA n 
1 12  ALA n 
1 13  VAL n 
1 14  GLU n 
1 15  ARG n 
1 16  SER n 
1 17  LYS n 
1 18  MET n 
1 19  ILE n 
1 20  GLU n 
1 21  LYS n 
1 22  GLN n 
1 23  LEU n 
1 24  GLN n 
1 25  LYS n 
1 26  ASP n 
1 27  LYS n 
1 28  GLN n 
1 29  VAL n 
1 30  TYR n 
1 31  ARG n 
1 32  ARG n 
1 33  THR n 
1 34  LEU n 
1 35  ARG n 
1 36  LEU n 
1 37  LEU n 
1 38  LEU n 
1 39  LEU n 
1 40  GLY n 
1 41  ALA n 
1 42  ASP n 
1 43  ASN n 
1 44  SER n 
1 45  GLY n 
1 46  LYS n 
1 47  SER n 
1 48  THR n 
1 49  ILE n 
1 50  VAL n 
1 51  LYS n 
1 52  GLN n 
1 53  MET n 
1 54  ARG n 
1 55  ILE n 
1 56  TYR n 
1 57  HIS n 
1 58  VAL n 
1 59  ASN n 
1 60  GLY n 
1 61  TYR n 
1 62  SER n 
1 63  GLU n 
1 64  GLU n 
1 65  GLU n 
1 66  CYS n 
1 67  LYS n 
1 68  GLN n 
1 69  TYR n 
1 70  LYS n 
1 71  ALA n 
1 72  VAL n 
1 73  VAL n 
1 74  TYR n 
1 75  SER n 
1 76  ASN n 
1 77  THR n 
1 78  ILE n 
1 79  GLN n 
1 80  SER n 
1 81  ILE n 
1 82  ILE n 
1 83  ALA n 
1 84  ILE n 
1 85  ILE n 
1 86  ARG n 
1 87  ALA n 
1 88  MET n 
1 89  GLY n 
1 90  ARG n 
1 91  LEU n 
1 92  LYS n 
1 93  ILE n 
1 94  ASP n 
1 95  PHE n 
1 96  GLY n 
1 97  ASP n 
1 98  SER n 
1 99  ALA n 
1 100 ARG n 
1 101 ALA n 
1 102 ASP n 
1 103 ASP n 
1 104 ALA n 
1 105 ARG n 
1 106 GLN n 
1 107 LEU n 
1 108 PHE n 
1 109 VAL n 
1 110 LEU n 
1 111 ALA n 
1 112 GLY n 
1 113 ALA n 
1 114 ALA n 
1 115 GLU n 
1 116 GLU n 
1 117 GLY n 
1 118 PHE n 
1 119 MET n 
1 120 THR n 
1 121 ALA n 
1 122 GLU n 
1 123 LEU n 
1 124 ALA n 
1 125 GLY n 
1 126 VAL n 
1 127 ILE n 
1 128 LYS n 
1 129 ARG n 
1 130 LEU n 
1 131 TRP n 
1 132 LYS n 
1 133 ASP n 
1 134 SER n 
1 135 GLY n 
1 136 VAL n 
1 137 GLN n 
1 138 ALA n 
1 139 CYS n 
1 140 PHE n 
1 141 ASN n 
1 142 ARG n 
1 143 SER n 
1 144 ARG n 
1 145 GLU n 
1 146 TYR n 
1 147 GLN n 
1 148 LEU n 
1 149 ASN n 
1 150 ASP n 
1 151 SER n 
1 152 ALA n 
1 153 ALA n 
1 154 TYR n 
1 155 TYR n 
1 156 LEU n 
1 157 ASN n 
1 158 ASP n 
1 159 LEU n 
1 160 ASP n 
1 161 ARG n 
1 162 ILE n 
1 163 ALA n 
1 164 GLN n 
1 165 PRO n 
1 166 ASN n 
1 167 TYR n 
1 168 ILE n 
1 169 PRO n 
1 170 THR n 
1 171 GLN n 
1 172 GLN n 
1 173 ASP n 
1 174 VAL n 
1 175 LEU n 
1 176 ARG n 
1 177 THR n 
1 178 ARG n 
1 179 VAL n 
1 180 LYS n 
1 181 THR n 
1 182 SER n 
1 183 GLY n 
1 184 ILE n 
1 185 PHE n 
1 186 GLU n 
1 187 THR n 
1 188 LYS n 
1 189 PHE n 
1 190 GLN n 
1 191 VAL n 
1 192 ASP n 
1 193 LYS n 
1 194 VAL n 
1 195 ASN n 
1 196 PHE n 
1 197 HIS n 
1 198 MET n 
1 199 PHE n 
1 200 ASP n 
1 201 VAL n 
1 202 GLY n 
1 203 ALA n 
1 204 GLN n 
1 205 ARG n 
1 206 ASP n 
1 207 GLU n 
1 208 ARG n 
1 209 ARG n 
1 210 LYS n 
1 211 TRP n 
1 212 ILE n 
1 213 GLN n 
1 214 CYS n 
1 215 PHE n 
1 216 ASN n 
1 217 ASP n 
1 218 VAL n 
1 219 THR n 
1 220 ALA n 
1 221 ILE n 
1 222 ILE n 
1 223 PHE n 
1 224 VAL n 
1 225 VAL n 
1 226 ASP n 
1 227 SER n 
1 228 SER n 
1 229 ASP n 
1 230 TYR n 
1 231 ASN n 
1 232 ARG n 
1 233 LEU n 
1 234 GLN n 
1 235 GLU n 
1 236 ALA n 
1 237 LEU n 
1 238 ASN n 
1 239 ASP n 
1 240 PHE n 
1 241 LYS n 
1 242 SER n 
1 243 ILE n 
1 244 TRP n 
1 245 ASN n 
1 246 ASN n 
1 247 ARG n 
1 248 TRP n 
1 249 LEU n 
1 250 ARG n 
1 251 THR n 
1 252 ILE n 
1 253 SER n 
1 254 VAL n 
1 255 ILE n 
1 256 LEU n 
1 257 PHE n 
1 258 LEU n 
1 259 ASN n 
1 260 LYS n 
1 261 GLN n 
1 262 ASP n 
1 263 LEU n 
1 264 LEU n 
1 265 ALA n 
1 266 GLU n 
1 267 LYS n 
1 268 VAL n 
1 269 LEU n 
1 270 ALA n 
1 271 GLY n 
1 272 LYS n 
1 273 SER n 
1 274 LYS n 
1 275 ILE n 
1 276 GLU n 
1 277 ASP n 
1 278 TYR n 
1 279 PHE n 
1 280 PRO n 
1 281 GLU n 
1 282 PHE n 
1 283 ALA n 
1 284 ARG n 
1 285 TYR n 
1 286 THR n 
1 287 THR n 
1 288 PRO n 
1 289 GLU n 
1 290 ASP n 
1 291 ALA n 
1 292 THR n 
1 293 PRO n 
1 294 GLU n 
1 295 PRO n 
1 296 GLY n 
1 297 GLU n 
1 298 ASP n 
1 299 PRO n 
1 300 ARG n 
1 301 VAL n 
1 302 THR n 
1 303 ARG n 
1 304 ALA n 
1 305 LYS n 
1 306 TYR n 
1 307 PHE n 
1 308 ILE n 
1 309 ARG n 
1 310 LYS n 
1 311 GLU n 
1 312 PHE n 
1 313 VAL n 
1 314 ASP n 
1 315 ILE n 
1 316 SER n 
1 317 THR n 
1 318 ALA n 
1 319 SER n 
1 320 GLY n 
1 321 ASP n 
1 322 GLY n 
1 323 ARG n 
1 324 HIS n 
1 325 ILE n 
1 326 CYS n 
1 327 TYR n 
1 328 PRO n 
1 329 HIS n 
1 330 PHE n 
1 331 THR n 
1 332 CYS n 
1 333 SER n 
1 334 VAL n 
1 335 ASP n 
1 336 THR n 
1 337 GLU n 
1 338 ASN n 
1 339 ALA n 
1 340 ARG n 
1 341 ARG n 
1 342 ILE n 
1 343 PHE n 
1 344 ASN n 
1 345 ASP n 
1 346 CYS n 
1 347 LYS n 
1 348 ASP n 
1 349 ILE n 
1 350 ILE n 
1 351 LEU n 
1 352 GLN n 
1 353 MET n 
1 354 ASN n 
1 355 LEU n 
1 356 ARG n 
1 357 GLU n 
1 358 TYR n 
1 359 ASN n 
1 360 LEU n 
1 361 VAL n 
2 1   MET n 
2 2   HIS n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   GLY n 
2 9   SER n 
2 10  LEU n 
2 11  LEU n 
2 12  GLN n 
2 13  SER n 
2 14  GLU n 
2 15  LEU n 
2 16  ASP n 
2 17  GLN n 
2 18  LEU n 
2 19  ARG n 
2 20  GLN n 
2 21  GLU n 
2 22  ALA n 
2 23  GLU n 
2 24  GLN n 
2 25  LEU n 
2 26  LYS n 
2 27  ASN n 
2 28  GLN n 
2 29  ILE n 
2 30  ARG n 
2 31  ASP n 
2 32  ALA n 
2 33  ARG n 
2 34  LYS n 
2 35  ALA n 
2 36  CYS n 
2 37  ALA n 
2 38  ASP n 
2 39  ALA n 
2 40  THR n 
2 41  LEU n 
2 42  SER n 
2 43  GLN n 
2 44  ILE n 
2 45  THR n 
2 46  ASN n 
2 47  ASN n 
2 48  ILE n 
2 49  ASP n 
2 50  PRO n 
2 51  VAL n 
2 52  GLY n 
2 53  ARG n 
2 54  ILE n 
2 55  GLN n 
2 56  MET n 
2 57  ARG n 
2 58  THR n 
2 59  ARG n 
2 60  ARG n 
2 61  THR n 
2 62  LEU n 
2 63  ARG n 
2 64  GLY n 
2 65  HIS n 
2 66  LEU n 
2 67  ALA n 
2 68  LYS n 
2 69  ILE n 
2 70  TYR n 
2 71  ALA n 
2 72  MET n 
2 73  HIS n 
2 74  TRP n 
2 75  GLY n 
2 76  THR n 
2 77  ASP n 
2 78  SER n 
2 79  ARG n 
2 80  LEU n 
2 81  LEU n 
2 82  VAL n 
2 83  SER n 
2 84  ALA n 
2 85  SER n 
2 86  GLN n 
2 87  ASP n 
2 88  GLY n 
2 89  LYS n 
2 90  LEU n 
2 91  ILE n 
2 92  ILE n 
2 93  TRP n 
2 94  ASP n 
2 95  SER n 
2 96  TYR n 
2 97  THR n 
2 98  THR n 
2 99  ASN n 
2 100 LYS n 
2 101 VAL n 
2 102 HIS n 
2 103 ALA n 
2 104 ILE n 
2 105 PRO n 
2 106 LEU n 
2 107 ARG n 
2 108 SER n 
2 109 SER n 
2 110 TRP n 
2 111 VAL n 
2 112 MET n 
2 113 THR n 
2 114 CYS n 
2 115 ALA n 
2 116 TYR n 
2 117 ALA n 
2 118 PRO n 
2 119 SER n 
2 120 GLY n 
2 121 ASN n 
2 122 TYR n 
2 123 VAL n 
2 124 ALA n 
2 125 CYS n 
2 126 GLY n 
2 127 GLY n 
2 128 LEU n 
2 129 ASP n 
2 130 ASN n 
2 131 ILE n 
2 132 CYS n 
2 133 SER n 
2 134 ILE n 
2 135 TYR n 
2 136 ASN n 
2 137 LEU n 
2 138 LYS n 
2 139 THR n 
2 140 ARG n 
2 141 GLU n 
2 142 GLY n 
2 143 ASN n 
2 144 VAL n 
2 145 ARG n 
2 146 VAL n 
2 147 SER n 
2 148 ARG n 
2 149 GLU n 
2 150 LEU n 
2 151 ALA n 
2 152 GLY n 
2 153 HIS n 
2 154 THR n 
2 155 GLY n 
2 156 TYR n 
2 157 LEU n 
2 158 SER n 
2 159 CYS n 
2 160 CYS n 
2 161 ARG n 
2 162 PHE n 
2 163 LEU n 
2 164 ASP n 
2 165 ASP n 
2 166 ASN n 
2 167 GLN n 
2 168 ILE n 
2 169 VAL n 
2 170 THR n 
2 171 SER n 
2 172 SER n 
2 173 GLY n 
2 174 ASP n 
2 175 THR n 
2 176 THR n 
2 177 CYS n 
2 178 ALA n 
2 179 LEU n 
2 180 TRP n 
2 181 ASP n 
2 182 ILE n 
2 183 GLU n 
2 184 THR n 
2 185 GLY n 
2 186 GLN n 
2 187 GLN n 
2 188 THR n 
2 189 THR n 
2 190 THR n 
2 191 PHE n 
2 192 THR n 
2 193 GLY n 
2 194 HIS n 
2 195 THR n 
2 196 GLY n 
2 197 ASP n 
2 198 VAL n 
2 199 MET n 
2 200 SER n 
2 201 LEU n 
2 202 SER n 
2 203 LEU n 
2 204 ALA n 
2 205 PRO n 
2 206 ASP n 
2 207 THR n 
2 208 ARG n 
2 209 LEU n 
2 210 PHE n 
2 211 VAL n 
2 212 SER n 
2 213 GLY n 
2 214 ALA n 
2 215 CYS n 
2 216 ASP n 
2 217 ALA n 
2 218 SER n 
2 219 ALA n 
2 220 LYS n 
2 221 LEU n 
2 222 TRP n 
2 223 ASP n 
2 224 VAL n 
2 225 ARG n 
2 226 GLU n 
2 227 GLY n 
2 228 MET n 
2 229 CYS n 
2 230 ARG n 
2 231 GLN n 
2 232 THR n 
2 233 PHE n 
2 234 THR n 
2 235 GLY n 
2 236 HIS n 
2 237 GLU n 
2 238 SER n 
2 239 ASP n 
2 240 ILE n 
2 241 ASN n 
2 242 ALA n 
2 243 ILE n 
2 244 CYS n 
2 245 PHE n 
2 246 PHE n 
2 247 PRO n 
2 248 ASN n 
2 249 GLY n 
2 250 ASN n 
2 251 ALA n 
2 252 PHE n 
2 253 ALA n 
2 254 THR n 
2 255 GLY n 
2 256 SER n 
2 257 ASP n 
2 258 ASP n 
2 259 ALA n 
2 260 THR n 
2 261 CYS n 
2 262 ARG n 
2 263 LEU n 
2 264 PHE n 
2 265 ASP n 
2 266 LEU n 
2 267 ARG n 
2 268 ALA n 
2 269 ASP n 
2 270 GLN n 
2 271 GLU n 
2 272 LEU n 
2 273 MET n 
2 274 THR n 
2 275 TYR n 
2 276 SER n 
2 277 HIS n 
2 278 ASP n 
2 279 ASN n 
2 280 ILE n 
2 281 ILE n 
2 282 CYS n 
2 283 GLY n 
2 284 ILE n 
2 285 THR n 
2 286 SER n 
2 287 VAL n 
2 288 SER n 
2 289 PHE n 
2 290 SER n 
2 291 LYS n 
2 292 SER n 
2 293 GLY n 
2 294 ARG n 
2 295 LEU n 
2 296 LEU n 
2 297 LEU n 
2 298 ALA n 
2 299 GLY n 
2 300 TYR n 
2 301 ASP n 
2 302 ASP n 
2 303 PHE n 
2 304 ASN n 
2 305 CYS n 
2 306 ASN n 
2 307 VAL n 
2 308 TRP n 
2 309 ASP n 
2 310 ALA n 
2 311 LEU n 
2 312 LYS n 
2 313 ALA n 
2 314 ASP n 
2 315 ARG n 
2 316 ALA n 
2 317 GLY n 
2 318 VAL n 
2 319 LEU n 
2 320 ALA n 
2 321 GLY n 
2 322 HIS n 
2 323 ASP n 
2 324 ASN n 
2 325 ARG n 
2 326 VAL n 
2 327 SER n 
2 328 CYS n 
2 329 LEU n 
2 330 GLY n 
2 331 VAL n 
2 332 THR n 
2 333 ASP n 
2 334 ASP n 
2 335 GLY n 
2 336 MET n 
2 337 ALA n 
2 338 VAL n 
2 339 ALA n 
2 340 THR n 
2 341 GLY n 
2 342 SER n 
2 343 TRP n 
2 344 ASP n 
2 345 SER n 
2 346 PHE n 
2 347 LEU n 
2 348 LYS n 
2 349 ILE n 
2 350 TRP n 
2 351 ASN n 
3 1   MET n 
3 2   VAL n 
3 3   GLN n 
3 4   LEU n 
3 5   VAL n 
3 6   GLU n 
3 7   SER n 
3 8   GLY n 
3 9   GLY n 
3 10  GLY n 
3 11  LEU n 
3 12  VAL n 
3 13  GLN n 
3 14  PRO n 
3 15  GLY n 
3 16  GLY n 
3 17  SER n 
3 18  ARG n 
3 19  LYS n 
3 20  LEU n 
3 21  SER n 
3 22  CYS n 
3 23  SER n 
3 24  ALA n 
3 25  SER n 
3 26  GLY n 
3 27  PHE n 
3 28  ALA n 
3 29  PHE n 
3 30  SER n 
3 31  SER n 
3 32  PHE n 
3 33  GLY n 
3 34  MET n 
3 35  HIS n 
3 36  TRP n 
3 37  VAL n 
3 38  ARG n 
3 39  GLN n 
3 40  ALA n 
3 41  PRO n 
3 42  GLU n 
3 43  LYS n 
3 44  GLY n 
3 45  LEU n 
3 46  GLU n 
3 47  TRP n 
3 48  VAL n 
3 49  ALA n 
3 50  TYR n 
3 51  ILE n 
3 52  SER n 
3 53  SER n 
3 54  GLY n 
3 55  SER n 
3 56  GLY n 
3 57  THR n 
3 58  ILE n 
3 59  TYR n 
3 60  TYR n 
3 61  ALA n 
3 62  ASP n 
3 63  THR n 
3 64  VAL n 
3 65  LYS n 
3 66  GLY n 
3 67  ARG n 
3 68  PHE n 
3 69  THR n 
3 70  ILE n 
3 71  SER n 
3 72  ARG n 
3 73  ASP n 
3 74  ASP n 
3 75  PRO n 
3 76  LYS n 
3 77  ASN n 
3 78  THR n 
3 79  LEU n 
3 80  PHE n 
3 81  LEU n 
3 82  GLN n 
3 83  MET n 
3 84  THR n 
3 85  SER n 
3 86  LEU n 
3 87  ARG n 
3 88  SER n 
3 89  GLU n 
3 90  ASP n 
3 91  THR n 
3 92  ALA n 
3 93  MET n 
3 94  TYR n 
3 95  TYR n 
3 96  CYS n 
3 97  VAL n 
3 98  ARG n 
3 99  SER n 
3 100 ILE n 
3 101 TYR n 
3 102 TYR n 
3 103 TYR n 
3 104 GLY n 
3 105 SER n 
3 106 SER n 
3 107 PRO n 
3 108 PHE n 
3 109 ASP n 
3 110 PHE n 
3 111 TRP n 
3 112 GLY n 
3 113 GLN n 
3 114 GLY n 
3 115 THR n 
3 116 THR n 
3 117 LEU n 
3 118 THR n 
3 119 VAL n 
3 120 SER n 
3 121 ALA n 
3 122 GLY n 
3 123 GLY n 
3 124 GLY n 
3 125 GLY n 
3 126 SER n 
3 127 GLY n 
3 128 GLY n 
3 129 GLY n 
3 130 GLY n 
3 131 SER n 
3 132 GLY n 
3 133 GLY n 
3 134 GLY n 
3 135 GLY n 
3 136 SER n 
3 137 ALA n 
3 138 ASP n 
3 139 ILE n 
3 140 VAL n 
3 141 MET n 
3 142 THR n 
3 143 GLN n 
3 144 ALA n 
3 145 THR n 
3 146 SER n 
3 147 SER n 
3 148 VAL n 
3 149 PRO n 
3 150 VAL n 
3 151 THR n 
3 152 PRO n 
3 153 GLY n 
3 154 GLU n 
3 155 SER n 
3 156 VAL n 
3 157 SER n 
3 158 ILE n 
3 159 SER n 
3 160 CYS n 
3 161 ARG n 
3 162 SER n 
3 163 SER n 
3 164 LYS n 
3 165 SER n 
3 166 LEU n 
3 167 LEU n 
3 168 HIS n 
3 169 SER n 
3 170 ASN n 
3 171 GLY n 
3 172 ASN n 
3 173 THR n 
3 174 TYR n 
3 175 LEU n 
3 176 TYR n 
3 177 TRP n 
3 178 PHE n 
3 179 LEU n 
3 180 GLN n 
3 181 ARG n 
3 182 PRO n 
3 183 GLY n 
3 184 GLN n 
3 185 SER n 
3 186 PRO n 
3 187 GLN n 
3 188 LEU n 
3 189 LEU n 
3 190 ILE n 
3 191 TYR n 
3 192 ARG n 
3 193 MET n 
3 194 SER n 
3 195 ASN n 
3 196 LEU n 
3 197 ALA n 
3 198 SER n 
3 199 GLY n 
3 200 VAL n 
3 201 PRO n 
3 202 ASP n 
3 203 ARG n 
3 204 PHE n 
3 205 SER n 
3 206 GLY n 
3 207 SER n 
3 208 GLY n 
3 209 SER n 
3 210 GLY n 
3 211 THR n 
3 212 ALA n 
3 213 PHE n 
3 214 THR n 
3 215 LEU n 
3 216 THR n 
3 217 ILE n 
3 218 SER n 
3 219 ARG n 
3 220 LEU n 
3 221 GLU n 
3 222 ALA n 
3 223 GLU n 
3 224 ASP n 
3 225 VAL n 
3 226 GLY n 
3 227 VAL n 
3 228 TYR n 
3 229 TYR n 
3 230 CYS n 
3 231 MET n 
3 232 GLN n 
3 233 HIS n 
3 234 LEU n 
3 235 GLU n 
3 236 TYR n 
3 237 PRO n 
3 238 LEU n 
3 239 THR n 
3 240 PHE n 
3 241 GLY n 
3 242 ALA n 
3 243 GLY n 
3 244 THR n 
3 245 LYS n 
3 246 LEU n 
3 247 GLU n 
3 248 LEU n 
4 1   MET n 
4 2   ALA n 
4 3   SER n 
4 4   ASN n 
4 5   ASN n 
4 6   THR n 
4 7   ALA n 
4 8   SER n 
4 9   ILE n 
4 10  ALA n 
4 11  GLN n 
4 12  ALA n 
4 13  ARG n 
4 14  LYS n 
4 15  LEU n 
4 16  VAL n 
4 17  GLU n 
4 18  GLN n 
4 19  LEU n 
4 20  LYS n 
4 21  MET n 
4 22  GLU n 
4 23  ALA n 
4 24  ASN n 
4 25  ILE n 
4 26  ASP n 
4 27  ARG n 
4 28  ILE n 
4 29  LYS n 
4 30  VAL n 
4 31  SER n 
4 32  LYS n 
4 33  ALA n 
4 34  ALA n 
4 35  ALA n 
4 36  ASP n 
4 37  LEU n 
4 38  MET n 
4 39  ALA n 
4 40  TYR n 
4 41  CYS n 
4 42  GLU n 
4 43  ALA n 
4 44  HIS n 
4 45  ALA n 
4 46  LYS n 
4 47  GLU n 
4 48  ASP n 
4 49  PRO n 
4 50  LEU n 
4 51  LEU n 
4 52  THR n 
4 53  PRO n 
4 54  VAL n 
4 55  PRO n 
4 56  ALA n 
4 57  SER n 
4 58  GLU n 
4 59  ASN n 
4 60  PRO n 
4 61  PHE n 
4 62  ARG n 
4 63  GLU n 
4 64  LYS n 
4 65  LYS n 
4 66  PHE n 
4 67  PHE n 
4 68  CYS n 
4 69  ALA n 
4 70  ILE n 
4 71  LEU n 
5 1   MET n 
5 2   GLU n 
5 3   ARG n 
5 4   LYS n 
5 5   PHE n 
5 6   MET n 
5 7   SER n 
5 8   LEU n 
5 9   GLN n 
5 10  PRO n 
5 11  SER n 
5 12  ILE n 
5 13  SER n 
5 14  VAL n 
5 15  SER n 
5 16  GLU n 
5 17  MET n 
5 18  GLU n 
5 19  PRO n 
5 20  ASN n 
5 21  GLY n 
5 22  THR n 
5 23  PHE n 
5 24  SER n 
5 25  ASN n 
5 26  ASN n 
5 27  ASN n 
5 28  SER n 
5 29  ARG n 
5 30  ASN n 
5 31  CYS n 
5 32  THR n 
5 33  ILE n 
5 34  GLU n 
5 35  ASN n 
5 36  PHE n 
5 37  LYS n 
5 38  ARG n 
5 39  GLU n 
5 40  PHE n 
5 41  PHE n 
5 42  PRO n 
5 43  ILE n 
5 44  VAL n 
5 45  TYR n 
5 46  LEU n 
5 47  ILE n 
5 48  ILE n 
5 49  PHE n 
5 50  PHE n 
5 51  TRP n 
5 52  GLY n 
5 53  VAL n 
5 54  LEU n 
5 55  GLY n 
5 56  ASN n 
5 57  GLY n 
5 58  LEU n 
5 59  SER n 
5 60  ILE n 
5 61  TYR n 
5 62  VAL n 
5 63  PHE n 
5 64  LEU n 
5 65  GLN n 
5 66  PRO n 
5 67  TYR n 
5 68  LYS n 
5 69  LYS n 
5 70  SER n 
5 71  THR n 
5 72  SER n 
5 73  VAL n 
5 74  ASN n 
5 75  VAL n 
5 76  PHE n 
5 77  MET n 
5 78  LEU n 
5 79  ASN n 
5 80  LEU n 
5 81  ALA n 
5 82  ILE n 
5 83  SER n 
5 84  ASP n 
5 85  LEU n 
5 86  LEU n 
5 87  PHE n 
5 88  ILE n 
5 89  SER n 
5 90  THR n 
5 91  LEU n 
5 92  PRO n 
5 93  PHE n 
5 94  ARG n 
5 95  ALA n 
5 96  ASP n 
5 97  TYR n 
5 98  TYR n 
5 99  LEU n 
5 100 ARG n 
5 101 GLY n 
5 102 SER n 
5 103 ASN n 
5 104 TRP n 
5 105 ILE n 
5 106 PHE n 
5 107 GLY n 
5 108 ASP n 
5 109 LEU n 
5 110 ALA n 
5 111 CYS n 
5 112 ARG n 
5 113 ILE n 
5 114 MET n 
5 115 SER n 
5 116 TYR n 
5 117 SER n 
5 118 LEU n 
5 119 TYR n 
5 120 VAL n 
5 121 ASN n 
5 122 MET n 
5 123 TYR n 
5 124 SER n 
5 125 SER n 
5 126 ILE n 
5 127 TYR n 
5 128 PHE n 
5 129 LEU n 
5 130 THR n 
5 131 VAL n 
5 132 LEU n 
5 133 SER n 
5 134 VAL n 
5 135 VAL n 
5 136 ARG n 
5 137 PHE n 
5 138 LEU n 
5 139 ALA n 
5 140 MET n 
5 141 VAL n 
5 142 HIS n 
5 143 PRO n 
5 144 PHE n 
5 145 ARG n 
5 146 LEU n 
5 147 LEU n 
5 148 HIS n 
5 149 VAL n 
5 150 THR n 
5 151 SER n 
5 152 ILE n 
5 153 ARG n 
5 154 SER n 
5 155 ALA n 
5 156 TRP n 
5 157 ILE n 
5 158 LEU n 
5 159 CYS n 
5 160 GLY n 
5 161 ILE n 
5 162 ILE n 
5 163 TRP n 
5 164 ILE n 
5 165 LEU n 
5 166 ILE n 
5 167 MET n 
5 168 ALA n 
5 169 SER n 
5 170 SER n 
5 171 ILE n 
5 172 MET n 
5 173 LEU n 
5 174 LEU n 
5 175 ASP n 
5 176 SER n 
5 177 GLY n 
5 178 SER n 
5 179 GLU n 
5 180 GLN n 
5 181 ASN n 
5 182 GLY n 
5 183 SER n 
5 184 VAL n 
5 185 THR n 
5 186 SER n 
5 187 CYS n 
5 188 LEU n 
5 189 GLU n 
5 190 LEU n 
5 191 ASN n 
5 192 LEU n 
5 193 TYR n 
5 194 LYS n 
5 195 ILE n 
5 196 ALA n 
5 197 LYS n 
5 198 LEU n 
5 199 GLN n 
5 200 THR n 
5 201 MET n 
5 202 ASN n 
5 203 TYR n 
5 204 ILE n 
5 205 ALA n 
5 206 LEU n 
5 207 VAL n 
5 208 VAL n 
5 209 GLY n 
5 210 CYS n 
5 211 LEU n 
5 212 LEU n 
5 213 PRO n 
5 214 PHE n 
5 215 PHE n 
5 216 THR n 
5 217 LEU n 
5 218 SER n 
5 219 ILE n 
5 220 CYS n 
5 221 TYR n 
5 222 LEU n 
5 223 LEU n 
5 224 ILE n 
5 225 ILE n 
5 226 ARG n 
5 227 VAL n 
5 228 LEU n 
5 229 LEU n 
5 230 LYS n 
5 231 VAL n 
5 232 GLU n 
5 233 VAL n 
5 234 PRO n 
5 235 GLU n 
5 236 SER n 
5 237 GLY n 
5 238 LEU n 
5 239 ARG n 
5 240 VAL n 
5 241 SER n 
5 242 HIS n 
5 243 ARG n 
5 244 LYS n 
5 245 ALA n 
5 246 LEU n 
5 247 THR n 
5 248 THR n 
5 249 ILE n 
5 250 ILE n 
5 251 ILE n 
5 252 THR n 
5 253 LEU n 
5 254 ILE n 
5 255 ILE n 
5 256 PHE n 
5 257 PHE n 
5 258 LEU n 
5 259 CYS n 
5 260 PHE n 
5 261 LEU n 
5 262 PRO n 
5 263 TYR n 
5 264 HIS n 
5 265 THR n 
5 266 LEU n 
5 267 ARG n 
5 268 THR n 
5 269 VAL n 
5 270 HIS n 
5 271 LEU n 
5 272 THR n 
5 273 THR n 
5 274 TRP n 
5 275 LYS n 
5 276 VAL n 
5 277 GLY n 
5 278 LEU n 
5 279 CYS n 
5 280 LYS n 
5 281 ASP n 
5 282 ARG n 
5 283 LEU n 
5 284 HIS n 
5 285 LYS n 
5 286 ALA n 
5 287 LEU n 
5 288 VAL n 
5 289 ILE n 
5 290 THR n 
5 291 LEU n 
5 292 ALA n 
5 293 LEU n 
5 294 ALA n 
5 295 ALA n 
5 296 ALA n 
5 297 ASN n 
5 298 ALA n 
5 299 CYS n 
5 300 PHE n 
5 301 ASN n 
5 302 PRO n 
5 303 LEU n 
5 304 LEU n 
5 305 TYR n 
5 306 TYR n 
5 307 PHE n 
5 308 ALA n 
5 309 GLY n 
5 310 GLU n 
5 311 ASN n 
5 312 PHE n 
5 313 LYS n 
5 314 ASP n 
5 315 ARG n 
5 316 LEU n 
5 317 LYS n 
5 318 SER n 
5 319 ALA n 
5 320 LEU n 
5 321 ARG n 
5 322 LYS n 
5 323 GLY n 
5 324 HIS n 
5 325 PRO n 
5 326 GLN n 
5 327 LYS n 
5 328 ALA n 
5 329 LYS n 
5 330 THR n 
5 331 LYS n 
5 332 CYS n 
5 333 VAL n 
5 334 PHE n 
5 335 PRO n 
5 336 VAL n 
5 337 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 361 human ? ?                                    ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? 
? ? ? ? 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 351 human ? GNB1                                 ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? 
? ? ? ? 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 248 ?     ? ?                                    ? ? ? ? ? ? 'Rattus norvegicus' 10116 ? ? ? ? 
? ? ? ? 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 71  human ? GNG2                                 ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? 
? ? ? ? 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 337 human ? 'CYSLTR2, CYSLT2, CYSLT2R, PSEC0146' ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? 
? ? ? ? 'Trichoplusia ni' 7111 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'    121.158 
GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'     131.173 
LTD non-polymer         . 
;(5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid
;
? 'C25 H40 N2 O6 S' 496.660 
LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLY 2   2   ?   ?   ?   A . n 
A 1 3   CYS 3   3   ?   ?   ?   A . n 
A 1 4   THR 4   4   ?   ?   ?   A . n 
A 1 5   LEU 5   5   5   LEU LEU A . n 
A 1 6   SER 6   6   6   SER SER A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   GLU 8   8   8   GLU GLU A . n 
A 1 9   ASP 9   9   9   ASP ASP A . n 
A 1 10  LYS 10  10  10  LYS LYS A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  ALA 12  12  12  ALA ALA A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  SER 16  16  16  SER SER A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  MET 18  18  18  MET MET A . n 
A 1 19  ILE 19  19  19  ILE ILE A . n 
A 1 20  GLU 20  20  20  GLU GLU A . n 
A 1 21  LYS 21  21  21  LYS LYS A . n 
A 1 22  GLN 22  22  22  GLN GLN A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  GLN 24  24  24  GLN GLN A . n 
A 1 25  LYS 25  25  25  LYS LYS A . n 
A 1 26  ASP 26  26  26  ASP ASP A . n 
A 1 27  LYS 27  27  27  LYS LYS A . n 
A 1 28  GLN 28  28  28  GLN GLN A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  TYR 30  30  30  TYR TYR A . n 
A 1 31  ARG 31  31  31  ARG ARG A . n 
A 1 32  ARG 32  32  32  ARG ARG A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  LEU 34  34  34  LEU LEU A . n 
A 1 35  ARG 35  35  35  ARG ARG A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  ASP 42  42  42  ASP ASP A . n 
A 1 43  ASN 43  43  43  ASN ASN A . n 
A 1 44  SER 44  44  44  SER SER A . n 
A 1 45  GLY 45  45  45  GLY GLY A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  SER 47  47  47  SER SER A . n 
A 1 48  THR 48  48  48  THR THR A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  GLN 52  52  52  GLN GLN A . n 
A 1 53  MET 53  53  53  MET MET A . n 
A 1 54  ARG 54  54  54  ARG ARG A . n 
A 1 55  ILE 55  55  55  ILE ILE A . n 
A 1 56  TYR 56  56  ?   ?   ?   A . n 
A 1 57  HIS 57  57  ?   ?   ?   A . n 
A 1 58  VAL 58  58  ?   ?   ?   A . n 
A 1 59  ASN 59  59  ?   ?   ?   A . n 
A 1 60  GLY 60  60  ?   ?   ?   A . n 
A 1 61  TYR 61  61  ?   ?   ?   A . n 
A 1 62  SER 62  62  ?   ?   ?   A . n 
A 1 63  GLU 63  63  ?   ?   ?   A . n 
A 1 64  GLU 64  64  ?   ?   ?   A . n 
A 1 65  GLU 65  65  ?   ?   ?   A . n 
A 1 66  CYS 66  66  ?   ?   ?   A . n 
A 1 67  LYS 67  67  ?   ?   ?   A . n 
A 1 68  GLN 68  68  ?   ?   ?   A . n 
A 1 69  TYR 69  69  ?   ?   ?   A . n 
A 1 70  LYS 70  70  ?   ?   ?   A . n 
A 1 71  ALA 71  71  ?   ?   ?   A . n 
A 1 72  VAL 72  72  ?   ?   ?   A . n 
A 1 73  VAL 73  73  ?   ?   ?   A . n 
A 1 74  TYR 74  74  ?   ?   ?   A . n 
A 1 75  SER 75  75  ?   ?   ?   A . n 
A 1 76  ASN 76  76  ?   ?   ?   A . n 
A 1 77  THR 77  77  ?   ?   ?   A . n 
A 1 78  ILE 78  78  ?   ?   ?   A . n 
A 1 79  GLN 79  79  ?   ?   ?   A . n 
A 1 80  SER 80  80  ?   ?   ?   A . n 
A 1 81  ILE 81  81  ?   ?   ?   A . n 
A 1 82  ILE 82  82  ?   ?   ?   A . n 
A 1 83  ALA 83  83  ?   ?   ?   A . n 
A 1 84  ILE 84  84  ?   ?   ?   A . n 
A 1 85  ILE 85  85  ?   ?   ?   A . n 
A 1 86  ARG 86  86  ?   ?   ?   A . n 
A 1 87  ALA 87  87  ?   ?   ?   A . n 
A 1 88  MET 88  88  ?   ?   ?   A . n 
A 1 89  GLY 89  89  ?   ?   ?   A . n 
A 1 90  ARG 90  90  ?   ?   ?   A . n 
A 1 91  LEU 91  91  ?   ?   ?   A . n 
A 1 92  LYS 92  92  ?   ?   ?   A . n 
A 1 93  ILE 93  93  ?   ?   ?   A . n 
A 1 94  ASP 94  94  ?   ?   ?   A . n 
A 1 95  PHE 95  95  ?   ?   ?   A . n 
A 1 96  GLY 96  96  ?   ?   ?   A . n 
A 1 97  ASP 97  97  ?   ?   ?   A . n 
A 1 98  SER 98  98  ?   ?   ?   A . n 
A 1 99  ALA 99  99  ?   ?   ?   A . n 
A 1 100 ARG 100 100 ?   ?   ?   A . n 
A 1 101 ALA 101 101 ?   ?   ?   A . n 
A 1 102 ASP 102 102 ?   ?   ?   A . n 
A 1 103 ASP 103 103 ?   ?   ?   A . n 
A 1 104 ALA 104 104 ?   ?   ?   A . n 
A 1 105 ARG 105 105 ?   ?   ?   A . n 
A 1 106 GLN 106 106 ?   ?   ?   A . n 
A 1 107 LEU 107 107 ?   ?   ?   A . n 
A 1 108 PHE 108 108 ?   ?   ?   A . n 
A 1 109 VAL 109 109 ?   ?   ?   A . n 
A 1 110 LEU 110 110 ?   ?   ?   A . n 
A 1 111 ALA 111 111 ?   ?   ?   A . n 
A 1 112 GLY 112 112 ?   ?   ?   A . n 
A 1 113 ALA 113 113 ?   ?   ?   A . n 
A 1 114 ALA 114 114 ?   ?   ?   A . n 
A 1 115 GLU 115 115 ?   ?   ?   A . n 
A 1 116 GLU 116 116 ?   ?   ?   A . n 
A 1 117 GLY 117 117 ?   ?   ?   A . n 
A 1 118 PHE 118 118 ?   ?   ?   A . n 
A 1 119 MET 119 119 ?   ?   ?   A . n 
A 1 120 THR 120 120 ?   ?   ?   A . n 
A 1 121 ALA 121 121 ?   ?   ?   A . n 
A 1 122 GLU 122 122 ?   ?   ?   A . n 
A 1 123 LEU 123 123 ?   ?   ?   A . n 
A 1 124 ALA 124 124 ?   ?   ?   A . n 
A 1 125 GLY 125 125 ?   ?   ?   A . n 
A 1 126 VAL 126 126 ?   ?   ?   A . n 
A 1 127 ILE 127 127 ?   ?   ?   A . n 
A 1 128 LYS 128 128 ?   ?   ?   A . n 
A 1 129 ARG 129 129 ?   ?   ?   A . n 
A 1 130 LEU 130 130 ?   ?   ?   A . n 
A 1 131 TRP 131 131 ?   ?   ?   A . n 
A 1 132 LYS 132 132 ?   ?   ?   A . n 
A 1 133 ASP 133 133 ?   ?   ?   A . n 
A 1 134 SER 134 134 ?   ?   ?   A . n 
A 1 135 GLY 135 135 ?   ?   ?   A . n 
A 1 136 VAL 136 136 ?   ?   ?   A . n 
A 1 137 GLN 137 137 ?   ?   ?   A . n 
A 1 138 ALA 138 138 ?   ?   ?   A . n 
A 1 139 CYS 139 139 ?   ?   ?   A . n 
A 1 140 PHE 140 140 ?   ?   ?   A . n 
A 1 141 ASN 141 141 ?   ?   ?   A . n 
A 1 142 ARG 142 142 ?   ?   ?   A . n 
A 1 143 SER 143 143 ?   ?   ?   A . n 
A 1 144 ARG 144 144 ?   ?   ?   A . n 
A 1 145 GLU 145 145 ?   ?   ?   A . n 
A 1 146 TYR 146 146 ?   ?   ?   A . n 
A 1 147 GLN 147 147 ?   ?   ?   A . n 
A 1 148 LEU 148 148 ?   ?   ?   A . n 
A 1 149 ASN 149 149 ?   ?   ?   A . n 
A 1 150 ASP 150 150 ?   ?   ?   A . n 
A 1 151 SER 151 151 ?   ?   ?   A . n 
A 1 152 ALA 152 152 ?   ?   ?   A . n 
A 1 153 ALA 153 153 ?   ?   ?   A . n 
A 1 154 TYR 154 154 ?   ?   ?   A . n 
A 1 155 TYR 155 155 ?   ?   ?   A . n 
A 1 156 LEU 156 156 ?   ?   ?   A . n 
A 1 157 ASN 157 157 ?   ?   ?   A . n 
A 1 158 ASP 158 158 ?   ?   ?   A . n 
A 1 159 LEU 159 159 ?   ?   ?   A . n 
A 1 160 ASP 160 160 ?   ?   ?   A . n 
A 1 161 ARG 161 161 ?   ?   ?   A . n 
A 1 162 ILE 162 162 ?   ?   ?   A . n 
A 1 163 ALA 163 163 ?   ?   ?   A . n 
A 1 164 GLN 164 164 ?   ?   ?   A . n 
A 1 165 PRO 165 165 ?   ?   ?   A . n 
A 1 166 ASN 166 166 ?   ?   ?   A . n 
A 1 167 TYR 167 167 ?   ?   ?   A . n 
A 1 168 ILE 168 168 ?   ?   ?   A . n 
A 1 169 PRO 169 169 ?   ?   ?   A . n 
A 1 170 THR 170 170 ?   ?   ?   A . n 
A 1 171 GLN 171 171 ?   ?   ?   A . n 
A 1 172 GLN 172 172 ?   ?   ?   A . n 
A 1 173 ASP 173 173 ?   ?   ?   A . n 
A 1 174 VAL 174 174 ?   ?   ?   A . n 
A 1 175 LEU 175 175 ?   ?   ?   A . n 
A 1 176 ARG 176 176 ?   ?   ?   A . n 
A 1 177 THR 177 177 ?   ?   ?   A . n 
A 1 178 ARG 178 178 ?   ?   ?   A . n 
A 1 179 VAL 179 179 ?   ?   ?   A . n 
A 1 180 LYS 180 180 ?   ?   ?   A . n 
A 1 181 THR 181 181 181 THR THR A . n 
A 1 182 SER 182 182 182 SER SER A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 ILE 184 184 184 ILE ILE A . n 
A 1 185 PHE 185 185 185 PHE PHE A . n 
A 1 186 GLU 186 186 186 GLU GLU A . n 
A 1 187 THR 187 187 187 THR THR A . n 
A 1 188 LYS 188 188 188 LYS LYS A . n 
A 1 189 PHE 189 189 189 PHE PHE A . n 
A 1 190 GLN 190 190 190 GLN GLN A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 ASP 192 192 192 ASP ASP A . n 
A 1 193 LYS 193 193 193 LYS LYS A . n 
A 1 194 VAL 194 194 194 VAL VAL A . n 
A 1 195 ASN 195 195 195 ASN ASN A . n 
A 1 196 PHE 196 196 196 PHE PHE A . n 
A 1 197 HIS 197 197 197 HIS HIS A . n 
A 1 198 MET 198 198 198 MET MET A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 ALA 203 203 203 ALA ALA A . n 
A 1 204 GLN 204 204 204 GLN GLN A . n 
A 1 205 ARG 205 205 205 ARG ARG A . n 
A 1 206 ASP 206 206 206 ASP ASP A . n 
A 1 207 GLU 207 207 207 GLU GLU A . n 
A 1 208 ARG 208 208 208 ARG ARG A . n 
A 1 209 ARG 209 209 209 ARG ARG A . n 
A 1 210 LYS 210 210 210 LYS LYS A . n 
A 1 211 TRP 211 211 211 TRP TRP A . n 
A 1 212 ILE 212 212 212 ILE ILE A . n 
A 1 213 GLN 213 213 213 GLN GLN A . n 
A 1 214 CYS 214 214 214 CYS CYS A . n 
A 1 215 PHE 215 215 215 PHE PHE A . n 
A 1 216 ASN 216 216 216 ASN ASN A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 VAL 218 218 218 VAL VAL A . n 
A 1 219 THR 219 219 219 THR THR A . n 
A 1 220 ALA 220 220 220 ALA ALA A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 ASP 226 226 226 ASP ASP A . n 
A 1 227 SER 227 227 227 SER SER A . n 
A 1 228 SER 228 228 228 SER SER A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 TYR 230 230 230 TYR TYR A . n 
A 1 231 ASN 231 231 231 ASN ASN A . n 
A 1 232 ARG 232 232 232 ARG ARG A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 GLN 234 234 234 GLN GLN A . n 
A 1 235 GLU 235 235 235 GLU GLU A . n 
A 1 236 ALA 236 236 236 ALA ALA A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 ASN 238 238 238 ASN ASN A . n 
A 1 239 ASP 239 239 239 ASP ASP A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 LYS 241 241 241 LYS LYS A . n 
A 1 242 SER 242 242 242 SER SER A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 TRP 244 244 244 TRP TRP A . n 
A 1 245 ASN 245 245 245 ASN ASN A . n 
A 1 246 ASN 246 246 246 ASN ASN A . n 
A 1 247 ARG 247 247 247 ARG ARG A . n 
A 1 248 TRP 248 248 248 TRP TRP A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 ARG 250 250 250 ARG ARG A . n 
A 1 251 THR 251 251 251 THR THR A . n 
A 1 252 ILE 252 252 252 ILE ILE A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 ILE 255 255 255 ILE ILE A . n 
A 1 256 LEU 256 256 256 LEU LEU A . n 
A 1 257 PHE 257 257 257 PHE PHE A . n 
A 1 258 LEU 258 258 258 LEU LEU A . n 
A 1 259 ASN 259 259 259 ASN ASN A . n 
A 1 260 LYS 260 260 260 LYS LYS A . n 
A 1 261 GLN 261 261 261 GLN GLN A . n 
A 1 262 ASP 262 262 262 ASP ASP A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 LEU 264 264 264 LEU LEU A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 GLU 266 266 266 GLU GLU A . n 
A 1 267 LYS 267 267 267 LYS LYS A . n 
A 1 268 VAL 268 268 268 VAL VAL A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 LYS 272 272 272 LYS LYS A . n 
A 1 273 SER 273 273 273 SER SER A . n 
A 1 274 LYS 274 274 274 LYS LYS A . n 
A 1 275 ILE 275 275 275 ILE ILE A . n 
A 1 276 GLU 276 276 276 GLU GLU A . n 
A 1 277 ASP 277 277 277 ASP ASP A . n 
A 1 278 TYR 278 278 278 TYR TYR A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 PRO 280 280 280 PRO PRO A . n 
A 1 281 GLU 281 281 281 GLU GLU A . n 
A 1 282 PHE 282 282 282 PHE PHE A . n 
A 1 283 ALA 283 283 283 ALA ALA A . n 
A 1 284 ARG 284 284 284 ARG ARG A . n 
A 1 285 TYR 285 285 285 TYR TYR A . n 
A 1 286 THR 286 286 286 THR THR A . n 
A 1 287 THR 287 287 287 THR THR A . n 
A 1 288 PRO 288 288 288 PRO PRO A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 ASP 290 290 290 ASP ASP A . n 
A 1 291 ALA 291 291 291 ALA ALA A . n 
A 1 292 THR 292 292 292 THR THR A . n 
A 1 293 PRO 293 293 293 PRO PRO A . n 
A 1 294 GLU 294 294 294 GLU GLU A . n 
A 1 295 PRO 295 295 295 PRO PRO A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 GLU 297 297 297 GLU GLU A . n 
A 1 298 ASP 298 298 298 ASP ASP A . n 
A 1 299 PRO 299 299 299 PRO PRO A . n 
A 1 300 ARG 300 300 300 ARG ARG A . n 
A 1 301 VAL 301 301 301 VAL VAL A . n 
A 1 302 THR 302 302 302 THR THR A . n 
A 1 303 ARG 303 303 303 ARG ARG A . n 
A 1 304 ALA 304 304 304 ALA ALA A . n 
A 1 305 LYS 305 305 305 LYS LYS A . n 
A 1 306 TYR 306 306 306 TYR TYR A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 ILE 308 308 308 ILE ILE A . n 
A 1 309 ARG 309 309 309 ARG ARG A . n 
A 1 310 LYS 310 310 310 LYS LYS A . n 
A 1 311 GLU 311 311 311 GLU GLU A . n 
A 1 312 PHE 312 312 312 PHE PHE A . n 
A 1 313 VAL 313 313 313 VAL VAL A . n 
A 1 314 ASP 314 314 314 ASP ASP A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 THR 317 317 317 THR THR A . n 
A 1 318 ALA 318 318 318 ALA ALA A . n 
A 1 319 SER 319 319 319 SER SER A . n 
A 1 320 GLY 320 320 320 GLY GLY A . n 
A 1 321 ASP 321 321 321 ASP ASP A . n 
A 1 322 GLY 322 322 322 GLY GLY A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 HIS 324 324 324 HIS HIS A . n 
A 1 325 ILE 325 325 325 ILE ILE A . n 
A 1 326 CYS 326 326 326 CYS CYS A . n 
A 1 327 TYR 327 327 327 TYR TYR A . n 
A 1 328 PRO 328 328 328 PRO PRO A . n 
A 1 329 HIS 329 329 329 HIS HIS A . n 
A 1 330 PHE 330 330 330 PHE PHE A . n 
A 1 331 THR 331 331 331 THR THR A . n 
A 1 332 CYS 332 332 332 CYS CYS A . n 
A 1 333 SER 333 333 333 SER SER A . n 
A 1 334 VAL 334 334 334 VAL VAL A . n 
A 1 335 ASP 335 335 335 ASP ASP A . n 
A 1 336 THR 336 336 336 THR THR A . n 
A 1 337 GLU 337 337 337 GLU GLU A . n 
A 1 338 ASN 338 338 338 ASN ASN A . n 
A 1 339 ALA 339 339 339 ALA ALA A . n 
A 1 340 ARG 340 340 340 ARG ARG A . n 
A 1 341 ARG 341 341 341 ARG ARG A . n 
A 1 342 ILE 342 342 342 ILE ILE A . n 
A 1 343 PHE 343 343 343 PHE PHE A . n 
A 1 344 ASN 344 344 344 ASN ASN A . n 
A 1 345 ASP 345 345 345 ASP ASP A . n 
A 1 346 CYS 346 346 346 CYS CYS A . n 
A 1 347 LYS 347 347 347 LYS LYS A . n 
A 1 348 ASP 348 348 348 ASP ASP A . n 
A 1 349 ILE 349 349 349 ILE ILE A . n 
A 1 350 ILE 350 350 350 ILE ILE A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 GLN 352 352 352 GLN GLN A . n 
A 1 353 MET 353 353 353 MET MET A . n 
A 1 354 ASN 354 354 354 ASN ASN A . n 
A 1 355 LEU 355 355 355 LEU LEU A . n 
A 1 356 ARG 356 356 356 ARG ARG A . n 
A 1 357 GLU 357 357 357 GLU GLU A . n 
A 1 358 TYR 358 358 358 TYR TYR A . n 
A 1 359 ASN 359 359 359 ASN ASN A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 VAL 361 361 361 VAL VAL A . n 
B 2 1   MET 1   -5  ?   ?   ?   B . n 
B 2 2   HIS 2   -4  ?   ?   ?   B . n 
B 2 3   HIS 3   -3  ?   ?   ?   B . n 
B 2 4   HIS 4   -2  ?   ?   ?   B . n 
B 2 5   HIS 5   -1  ?   ?   ?   B . n 
B 2 6   HIS 6   0   ?   ?   ?   B . n 
B 2 7   HIS 7   1   ?   ?   ?   B . n 
B 2 8   GLY 8   2   ?   ?   ?   B . n 
B 2 9   SER 9   3   ?   ?   ?   B . n 
B 2 10  LEU 10  4   ?   ?   ?   B . n 
B 2 11  LEU 11  5   ?   ?   ?   B . n 
B 2 12  GLN 12  6   ?   ?   ?   B . n 
B 2 13  SER 13  7   ?   ?   ?   B . n 
B 2 14  GLU 14  8   8   GLU GLU B . n 
B 2 15  LEU 15  9   9   LEU LEU B . n 
B 2 16  ASP 16  10  10  ASP ASP B . n 
B 2 17  GLN 17  11  11  GLN GLN B . n 
B 2 18  LEU 18  12  12  LEU LEU B . n 
B 2 19  ARG 19  13  13  ARG ARG B . n 
B 2 20  GLN 20  14  14  GLN GLN B . n 
B 2 21  GLU 21  15  15  GLU GLU B . n 
B 2 22  ALA 22  16  16  ALA ALA B . n 
B 2 23  GLU 23  17  17  GLU GLU B . n 
B 2 24  GLN 24  18  18  GLN GLN B . n 
B 2 25  LEU 25  19  19  LEU LEU B . n 
B 2 26  LYS 26  20  20  LYS LYS B . n 
B 2 27  ASN 27  21  21  ASN ASN B . n 
B 2 28  GLN 28  22  22  GLN GLN B . n 
B 2 29  ILE 29  23  23  ILE ILE B . n 
B 2 30  ARG 30  24  24  ARG ARG B . n 
B 2 31  ASP 31  25  25  ASP ASP B . n 
B 2 32  ALA 32  26  26  ALA ALA B . n 
B 2 33  ARG 33  27  27  ARG ARG B . n 
B 2 34  LYS 34  28  28  LYS LYS B . n 
B 2 35  ALA 35  29  29  ALA ALA B . n 
B 2 36  CYS 36  30  30  CYS CYS B . n 
B 2 37  ALA 37  31  31  ALA ALA B . n 
B 2 38  ASP 38  32  32  ASP ASP B . n 
B 2 39  ALA 39  33  33  ALA ALA B . n 
B 2 40  THR 40  34  34  THR THR B . n 
B 2 41  LEU 41  35  35  LEU LEU B . n 
B 2 42  SER 42  36  36  SER SER B . n 
B 2 43  GLN 43  37  37  GLN GLN B . n 
B 2 44  ILE 44  38  38  ILE ILE B . n 
B 2 45  THR 45  39  39  THR THR B . n 
B 2 46  ASN 46  40  40  ASN ASN B . n 
B 2 47  ASN 47  41  41  ASN ASN B . n 
B 2 48  ILE 48  42  42  ILE ILE B . n 
B 2 49  ASP 49  43  43  ASP ASP B . n 
B 2 50  PRO 50  44  44  PRO PRO B . n 
B 2 51  VAL 51  45  45  VAL VAL B . n 
B 2 52  GLY 52  46  46  GLY GLY B . n 
B 2 53  ARG 53  47  47  ARG ARG B . n 
B 2 54  ILE 54  48  48  ILE ILE B . n 
B 2 55  GLN 55  49  49  GLN GLN B . n 
B 2 56  MET 56  50  50  MET MET B . n 
B 2 57  ARG 57  51  51  ARG ARG B . n 
B 2 58  THR 58  52  52  THR THR B . n 
B 2 59  ARG 59  53  53  ARG ARG B . n 
B 2 60  ARG 60  54  54  ARG ARG B . n 
B 2 61  THR 61  55  55  THR THR B . n 
B 2 62  LEU 62  56  56  LEU LEU B . n 
B 2 63  ARG 63  57  57  ARG ARG B . n 
B 2 64  GLY 64  58  58  GLY GLY B . n 
B 2 65  HIS 65  59  59  HIS HIS B . n 
B 2 66  LEU 66  60  60  LEU LEU B . n 
B 2 67  ALA 67  61  61  ALA ALA B . n 
B 2 68  LYS 68  62  62  LYS LYS B . n 
B 2 69  ILE 69  63  63  ILE ILE B . n 
B 2 70  TYR 70  64  64  TYR TYR B . n 
B 2 71  ALA 71  65  65  ALA ALA B . n 
B 2 72  MET 72  66  66  MET MET B . n 
B 2 73  HIS 73  67  67  HIS HIS B . n 
B 2 74  TRP 74  68  68  TRP TRP B . n 
B 2 75  GLY 75  69  69  GLY GLY B . n 
B 2 76  THR 76  70  70  THR THR B . n 
B 2 77  ASP 77  71  71  ASP ASP B . n 
B 2 78  SER 78  72  72  SER SER B . n 
B 2 79  ARG 79  73  73  ARG ARG B . n 
B 2 80  LEU 80  74  74  LEU LEU B . n 
B 2 81  LEU 81  75  75  LEU LEU B . n 
B 2 82  VAL 82  76  76  VAL VAL B . n 
B 2 83  SER 83  77  77  SER SER B . n 
B 2 84  ALA 84  78  78  ALA ALA B . n 
B 2 85  SER 85  79  79  SER SER B . n 
B 2 86  GLN 86  80  80  GLN GLN B . n 
B 2 87  ASP 87  81  81  ASP ASP B . n 
B 2 88  GLY 88  82  82  GLY GLY B . n 
B 2 89  LYS 89  83  83  LYS LYS B . n 
B 2 90  LEU 90  84  84  LEU LEU B . n 
B 2 91  ILE 91  85  85  ILE ILE B . n 
B 2 92  ILE 92  86  86  ILE ILE B . n 
B 2 93  TRP 93  87  87  TRP TRP B . n 
B 2 94  ASP 94  88  88  ASP ASP B . n 
B 2 95  SER 95  89  89  SER SER B . n 
B 2 96  TYR 96  90  90  TYR TYR B . n 
B 2 97  THR 97  91  91  THR THR B . n 
B 2 98  THR 98  92  92  THR THR B . n 
B 2 99  ASN 99  93  93  ASN ASN B . n 
B 2 100 LYS 100 94  94  LYS LYS B . n 
B 2 101 VAL 101 95  95  VAL VAL B . n 
B 2 102 HIS 102 96  96  HIS HIS B . n 
B 2 103 ALA 103 97  97  ALA ALA B . n 
B 2 104 ILE 104 98  98  ILE ILE B . n 
B 2 105 PRO 105 99  99  PRO PRO B . n 
B 2 106 LEU 106 100 100 LEU LEU B . n 
B 2 107 ARG 107 101 101 ARG ARG B . n 
B 2 108 SER 108 102 102 SER SER B . n 
B 2 109 SER 109 103 103 SER SER B . n 
B 2 110 TRP 110 104 104 TRP TRP B . n 
B 2 111 VAL 111 105 105 VAL VAL B . n 
B 2 112 MET 112 106 106 MET MET B . n 
B 2 113 THR 113 107 107 THR THR B . n 
B 2 114 CYS 114 108 108 CYS CYS B . n 
B 2 115 ALA 115 109 109 ALA ALA B . n 
B 2 116 TYR 116 110 110 TYR TYR B . n 
B 2 117 ALA 117 111 111 ALA ALA B . n 
B 2 118 PRO 118 112 112 PRO PRO B . n 
B 2 119 SER 119 113 113 SER SER B . n 
B 2 120 GLY 120 114 114 GLY GLY B . n 
B 2 121 ASN 121 115 115 ASN ASN B . n 
B 2 122 TYR 122 116 116 TYR TYR B . n 
B 2 123 VAL 123 117 117 VAL VAL B . n 
B 2 124 ALA 124 118 118 ALA ALA B . n 
B 2 125 CYS 125 119 119 CYS CYS B . n 
B 2 126 GLY 126 120 120 GLY GLY B . n 
B 2 127 GLY 127 121 121 GLY GLY B . n 
B 2 128 LEU 128 122 122 LEU LEU B . n 
B 2 129 ASP 129 123 123 ASP ASP B . n 
B 2 130 ASN 130 124 124 ASN ASN B . n 
B 2 131 ILE 131 125 125 ILE ILE B . n 
B 2 132 CYS 132 126 126 CYS CYS B . n 
B 2 133 SER 133 127 127 SER SER B . n 
B 2 134 ILE 134 128 128 ILE ILE B . n 
B 2 135 TYR 135 129 129 TYR TYR B . n 
B 2 136 ASN 136 130 130 ASN ASN B . n 
B 2 137 LEU 137 131 131 LEU LEU B . n 
B 2 138 LYS 138 132 132 LYS LYS B . n 
B 2 139 THR 139 133 133 THR THR B . n 
B 2 140 ARG 140 134 134 ARG ARG B . n 
B 2 141 GLU 141 135 135 GLU GLU B . n 
B 2 142 GLY 142 136 136 GLY GLY B . n 
B 2 143 ASN 143 137 137 ASN ASN B . n 
B 2 144 VAL 144 138 138 VAL VAL B . n 
B 2 145 ARG 145 139 139 ARG ARG B . n 
B 2 146 VAL 146 140 140 VAL VAL B . n 
B 2 147 SER 147 141 141 SER SER B . n 
B 2 148 ARG 148 142 142 ARG ARG B . n 
B 2 149 GLU 149 143 143 GLU GLU B . n 
B 2 150 LEU 150 144 144 LEU LEU B . n 
B 2 151 ALA 151 145 145 ALA ALA B . n 
B 2 152 GLY 152 146 146 GLY GLY B . n 
B 2 153 HIS 153 147 147 HIS HIS B . n 
B 2 154 THR 154 148 148 THR THR B . n 
B 2 155 GLY 155 149 149 GLY GLY B . n 
B 2 156 TYR 156 150 150 TYR TYR B . n 
B 2 157 LEU 157 151 151 LEU LEU B . n 
B 2 158 SER 158 152 152 SER SER B . n 
B 2 159 CYS 159 153 153 CYS CYS B . n 
B 2 160 CYS 160 154 154 CYS CYS B . n 
B 2 161 ARG 161 155 155 ARG ARG B . n 
B 2 162 PHE 162 156 156 PHE PHE B . n 
B 2 163 LEU 163 157 157 LEU LEU B . n 
B 2 164 ASP 164 158 158 ASP ASP B . n 
B 2 165 ASP 165 159 159 ASP ASP B . n 
B 2 166 ASN 166 160 160 ASN ASN B . n 
B 2 167 GLN 167 161 161 GLN GLN B . n 
B 2 168 ILE 168 162 162 ILE ILE B . n 
B 2 169 VAL 169 163 163 VAL VAL B . n 
B 2 170 THR 170 164 164 THR THR B . n 
B 2 171 SER 171 165 165 SER SER B . n 
B 2 172 SER 172 166 166 SER SER B . n 
B 2 173 GLY 173 167 167 GLY GLY B . n 
B 2 174 ASP 174 168 168 ASP ASP B . n 
B 2 175 THR 175 169 169 THR THR B . n 
B 2 176 THR 176 170 170 THR THR B . n 
B 2 177 CYS 177 171 171 CYS CYS B . n 
B 2 178 ALA 178 172 172 ALA ALA B . n 
B 2 179 LEU 179 173 173 LEU LEU B . n 
B 2 180 TRP 180 174 174 TRP TRP B . n 
B 2 181 ASP 181 175 175 ASP ASP B . n 
B 2 182 ILE 182 176 176 ILE ILE B . n 
B 2 183 GLU 183 177 177 GLU GLU B . n 
B 2 184 THR 184 178 178 THR THR B . n 
B 2 185 GLY 185 179 179 GLY GLY B . n 
B 2 186 GLN 186 180 180 GLN GLN B . n 
B 2 187 GLN 187 181 181 GLN GLN B . n 
B 2 188 THR 188 182 182 THR THR B . n 
B 2 189 THR 189 183 183 THR THR B . n 
B 2 190 THR 190 184 184 THR THR B . n 
B 2 191 PHE 191 185 185 PHE PHE B . n 
B 2 192 THR 192 186 186 THR THR B . n 
B 2 193 GLY 193 187 187 GLY GLY B . n 
B 2 194 HIS 194 188 188 HIS HIS B . n 
B 2 195 THR 195 189 189 THR THR B . n 
B 2 196 GLY 196 190 190 GLY GLY B . n 
B 2 197 ASP 197 191 191 ASP ASP B . n 
B 2 198 VAL 198 192 192 VAL VAL B . n 
B 2 199 MET 199 193 193 MET MET B . n 
B 2 200 SER 200 194 194 SER SER B . n 
B 2 201 LEU 201 195 195 LEU LEU B . n 
B 2 202 SER 202 196 196 SER SER B . n 
B 2 203 LEU 203 197 197 LEU LEU B . n 
B 2 204 ALA 204 198 198 ALA ALA B . n 
B 2 205 PRO 205 199 199 PRO PRO B . n 
B 2 206 ASP 206 200 200 ASP ASP B . n 
B 2 207 THR 207 201 201 THR THR B . n 
B 2 208 ARG 208 202 202 ARG ARG B . n 
B 2 209 LEU 209 203 203 LEU LEU B . n 
B 2 210 PHE 210 204 204 PHE PHE B . n 
B 2 211 VAL 211 205 205 VAL VAL B . n 
B 2 212 SER 212 206 206 SER SER B . n 
B 2 213 GLY 213 207 207 GLY GLY B . n 
B 2 214 ALA 214 208 208 ALA ALA B . n 
B 2 215 CYS 215 209 209 CYS CYS B . n 
B 2 216 ASP 216 210 210 ASP ASP B . n 
B 2 217 ALA 217 211 211 ALA ALA B . n 
B 2 218 SER 218 212 212 SER SER B . n 
B 2 219 ALA 219 213 213 ALA ALA B . n 
B 2 220 LYS 220 214 214 LYS LYS B . n 
B 2 221 LEU 221 215 215 LEU LEU B . n 
B 2 222 TRP 222 216 216 TRP TRP B . n 
B 2 223 ASP 223 217 217 ASP ASP B . n 
B 2 224 VAL 224 218 218 VAL VAL B . n 
B 2 225 ARG 225 219 219 ARG ARG B . n 
B 2 226 GLU 226 220 220 GLU GLU B . n 
B 2 227 GLY 227 221 221 GLY GLY B . n 
B 2 228 MET 228 222 222 MET MET B . n 
B 2 229 CYS 229 223 223 CYS CYS B . n 
B 2 230 ARG 230 224 224 ARG ARG B . n 
B 2 231 GLN 231 225 225 GLN GLN B . n 
B 2 232 THR 232 226 226 THR THR B . n 
B 2 233 PHE 233 227 227 PHE PHE B . n 
B 2 234 THR 234 228 228 THR THR B . n 
B 2 235 GLY 235 229 229 GLY GLY B . n 
B 2 236 HIS 236 230 230 HIS HIS B . n 
B 2 237 GLU 237 231 231 GLU GLU B . n 
B 2 238 SER 238 232 232 SER SER B . n 
B 2 239 ASP 239 233 233 ASP ASP B . n 
B 2 240 ILE 240 234 234 ILE ILE B . n 
B 2 241 ASN 241 235 235 ASN ASN B . n 
B 2 242 ALA 242 236 236 ALA ALA B . n 
B 2 243 ILE 243 237 237 ILE ILE B . n 
B 2 244 CYS 244 238 238 CYS CYS B . n 
B 2 245 PHE 245 239 239 PHE PHE B . n 
B 2 246 PHE 246 240 240 PHE PHE B . n 
B 2 247 PRO 247 241 241 PRO PRO B . n 
B 2 248 ASN 248 242 242 ASN ASN B . n 
B 2 249 GLY 249 243 243 GLY GLY B . n 
B 2 250 ASN 250 244 244 ASN ASN B . n 
B 2 251 ALA 251 245 245 ALA ALA B . n 
B 2 252 PHE 252 246 246 PHE PHE B . n 
B 2 253 ALA 253 247 247 ALA ALA B . n 
B 2 254 THR 254 248 248 THR THR B . n 
B 2 255 GLY 255 249 249 GLY GLY B . n 
B 2 256 SER 256 250 250 SER SER B . n 
B 2 257 ASP 257 251 251 ASP ASP B . n 
B 2 258 ASP 258 252 252 ASP ASP B . n 
B 2 259 ALA 259 253 253 ALA ALA B . n 
B 2 260 THR 260 254 254 THR THR B . n 
B 2 261 CYS 261 255 255 CYS CYS B . n 
B 2 262 ARG 262 256 256 ARG ARG B . n 
B 2 263 LEU 263 257 257 LEU LEU B . n 
B 2 264 PHE 264 258 258 PHE PHE B . n 
B 2 265 ASP 265 259 259 ASP ASP B . n 
B 2 266 LEU 266 260 260 LEU LEU B . n 
B 2 267 ARG 267 261 261 ARG ARG B . n 
B 2 268 ALA 268 262 262 ALA ALA B . n 
B 2 269 ASP 269 263 263 ASP ASP B . n 
B 2 270 GLN 270 264 264 GLN GLN B . n 
B 2 271 GLU 271 265 265 GLU GLU B . n 
B 2 272 LEU 272 266 266 LEU LEU B . n 
B 2 273 MET 273 267 267 MET MET B . n 
B 2 274 THR 274 268 268 THR THR B . n 
B 2 275 TYR 275 269 269 TYR TYR B . n 
B 2 276 SER 276 270 270 SER SER B . n 
B 2 277 HIS 277 271 271 HIS HIS B . n 
B 2 278 ASP 278 272 272 ASP ASP B . n 
B 2 279 ASN 279 273 273 ASN ASN B . n 
B 2 280 ILE 280 274 274 ILE ILE B . n 
B 2 281 ILE 281 275 275 ILE ILE B . n 
B 2 282 CYS 282 276 276 CYS CYS B . n 
B 2 283 GLY 283 277 277 GLY GLY B . n 
B 2 284 ILE 284 278 278 ILE ILE B . n 
B 2 285 THR 285 279 279 THR THR B . n 
B 2 286 SER 286 280 280 SER SER B . n 
B 2 287 VAL 287 281 281 VAL VAL B . n 
B 2 288 SER 288 282 282 SER SER B . n 
B 2 289 PHE 289 283 283 PHE PHE B . n 
B 2 290 SER 290 284 284 SER SER B . n 
B 2 291 LYS 291 285 285 LYS LYS B . n 
B 2 292 SER 292 286 286 SER SER B . n 
B 2 293 GLY 293 287 287 GLY GLY B . n 
B 2 294 ARG 294 288 288 ARG ARG B . n 
B 2 295 LEU 295 289 289 LEU LEU B . n 
B 2 296 LEU 296 290 290 LEU LEU B . n 
B 2 297 LEU 297 291 291 LEU LEU B . n 
B 2 298 ALA 298 292 292 ALA ALA B . n 
B 2 299 GLY 299 293 293 GLY GLY B . n 
B 2 300 TYR 300 294 294 TYR TYR B . n 
B 2 301 ASP 301 295 295 ASP ASP B . n 
B 2 302 ASP 302 296 296 ASP ASP B . n 
B 2 303 PHE 303 297 297 PHE PHE B . n 
B 2 304 ASN 304 298 298 ASN ASN B . n 
B 2 305 CYS 305 299 299 CYS CYS B . n 
B 2 306 ASN 306 300 300 ASN ASN B . n 
B 2 307 VAL 307 301 301 VAL VAL B . n 
B 2 308 TRP 308 302 302 TRP TRP B . n 
B 2 309 ASP 309 303 303 ASP ASP B . n 
B 2 310 ALA 310 304 304 ALA ALA B . n 
B 2 311 LEU 311 305 305 LEU LEU B . n 
B 2 312 LYS 312 306 306 LYS LYS B . n 
B 2 313 ALA 313 307 307 ALA ALA B . n 
B 2 314 ASP 314 308 308 ASP ASP B . n 
B 2 315 ARG 315 309 309 ARG ARG B . n 
B 2 316 ALA 316 310 310 ALA ALA B . n 
B 2 317 GLY 317 311 311 GLY GLY B . n 
B 2 318 VAL 318 312 312 VAL VAL B . n 
B 2 319 LEU 319 313 313 LEU LEU B . n 
B 2 320 ALA 320 314 314 ALA ALA B . n 
B 2 321 GLY 321 315 315 GLY GLY B . n 
B 2 322 HIS 322 316 316 HIS HIS B . n 
B 2 323 ASP 323 317 317 ASP ASP B . n 
B 2 324 ASN 324 318 318 ASN ASN B . n 
B 2 325 ARG 325 319 319 ARG ARG B . n 
B 2 326 VAL 326 320 320 VAL VAL B . n 
B 2 327 SER 327 321 321 SER SER B . n 
B 2 328 CYS 328 322 322 CYS CYS B . n 
B 2 329 LEU 329 323 323 LEU LEU B . n 
B 2 330 GLY 330 324 324 GLY GLY B . n 
B 2 331 VAL 331 325 325 VAL VAL B . n 
B 2 332 THR 332 326 326 THR THR B . n 
B 2 333 ASP 333 327 327 ASP ASP B . n 
B 2 334 ASP 334 328 328 ASP ASP B . n 
B 2 335 GLY 335 329 329 GLY GLY B . n 
B 2 336 MET 336 330 330 MET MET B . n 
B 2 337 ALA 337 331 331 ALA ALA B . n 
B 2 338 VAL 338 332 332 VAL VAL B . n 
B 2 339 ALA 339 333 333 ALA ALA B . n 
B 2 340 THR 340 334 334 THR THR B . n 
B 2 341 GLY 341 335 335 GLY GLY B . n 
B 2 342 SER 342 336 336 SER SER B . n 
B 2 343 TRP 343 337 337 TRP TRP B . n 
B 2 344 ASP 344 338 338 ASP ASP B . n 
B 2 345 SER 345 339 339 SER SER B . n 
B 2 346 PHE 346 340 340 PHE PHE B . n 
B 2 347 LEU 347 341 341 LEU LEU B . n 
B 2 348 LYS 348 342 342 LYS LYS B . n 
B 2 349 ILE 349 343 343 ILE ILE B . n 
B 2 350 TRP 350 344 344 TRP TRP B . n 
B 2 351 ASN 351 345 345 ASN ASN B . n 
C 3 1   MET 1   0   ?   ?   ?   E . n 
C 3 2   VAL 2   1   1   VAL VAL E . n 
C 3 3   GLN 3   2   2   GLN GLN E . n 
C 3 4   LEU 4   3   3   LEU LEU E . n 
C 3 5   VAL 5   4   4   VAL VAL E . n 
C 3 6   GLU 6   5   5   GLU GLU E . n 
C 3 7   SER 7   6   6   SER SER E . n 
C 3 8   GLY 8   7   7   GLY GLY E . n 
C 3 9   GLY 9   8   8   GLY GLY E . n 
C 3 10  GLY 10  9   9   GLY GLY E . n 
C 3 11  LEU 11  10  10  LEU LEU E . n 
C 3 12  VAL 12  11  11  VAL VAL E . n 
C 3 13  GLN 13  12  12  GLN GLN E . n 
C 3 14  PRO 14  13  13  PRO PRO E . n 
C 3 15  GLY 15  14  14  GLY GLY E . n 
C 3 16  GLY 16  15  15  GLY GLY E . n 
C 3 17  SER 17  16  16  SER SER E . n 
C 3 18  ARG 18  17  17  ARG ARG E . n 
C 3 19  LYS 19  18  18  LYS LYS E . n 
C 3 20  LEU 20  19  19  LEU LEU E . n 
C 3 21  SER 21  20  20  SER SER E . n 
C 3 22  CYS 22  21  21  CYS CYS E . n 
C 3 23  SER 23  22  22  SER SER E . n 
C 3 24  ALA 24  23  23  ALA ALA E . n 
C 3 25  SER 25  24  24  SER SER E . n 
C 3 26  GLY 26  25  25  GLY GLY E . n 
C 3 27  PHE 27  26  26  PHE PHE E . n 
C 3 28  ALA 28  27  27  ALA ALA E . n 
C 3 29  PHE 29  28  28  PHE PHE E . n 
C 3 30  SER 30  29  29  SER SER E . n 
C 3 31  SER 31  30  30  SER SER E . n 
C 3 32  PHE 32  31  31  PHE PHE E . n 
C 3 33  GLY 33  32  32  GLY GLY E . n 
C 3 34  MET 34  33  33  MET MET E . n 
C 3 35  HIS 35  34  34  HIS HIS E . n 
C 3 36  TRP 36  35  35  TRP TRP E . n 
C 3 37  VAL 37  36  36  VAL VAL E . n 
C 3 38  ARG 38  37  37  ARG ARG E . n 
C 3 39  GLN 39  38  38  GLN GLN E . n 
C 3 40  ALA 40  39  39  ALA ALA E . n 
C 3 41  PRO 41  40  40  PRO PRO E . n 
C 3 42  GLU 42  41  41  GLU GLU E . n 
C 3 43  LYS 43  42  42  LYS LYS E . n 
C 3 44  GLY 44  43  43  GLY GLY E . n 
C 3 45  LEU 45  44  44  LEU LEU E . n 
C 3 46  GLU 46  45  45  GLU GLU E . n 
C 3 47  TRP 47  46  46  TRP TRP E . n 
C 3 48  VAL 48  47  47  VAL VAL E . n 
C 3 49  ALA 49  48  48  ALA ALA E . n 
C 3 50  TYR 50  49  49  TYR TYR E . n 
C 3 51  ILE 51  50  50  ILE ILE E . n 
C 3 52  SER 52  51  51  SER SER E . n 
C 3 53  SER 53  52  52  SER SER E . n 
C 3 54  GLY 54  53  53  GLY GLY E . n 
C 3 55  SER 55  54  54  SER SER E . n 
C 3 56  GLY 56  55  55  GLY GLY E . n 
C 3 57  THR 57  56  56  THR THR E . n 
C 3 58  ILE 58  57  57  ILE ILE E . n 
C 3 59  TYR 59  58  58  TYR TYR E . n 
C 3 60  TYR 60  59  59  TYR TYR E . n 
C 3 61  ALA 61  60  60  ALA ALA E . n 
C 3 62  ASP 62  61  61  ASP ASP E . n 
C 3 63  THR 63  62  62  THR THR E . n 
C 3 64  VAL 64  63  63  VAL VAL E . n 
C 3 65  LYS 65  64  64  LYS LYS E . n 
C 3 66  GLY 66  65  65  GLY GLY E . n 
C 3 67  ARG 67  66  66  ARG ARG E . n 
C 3 68  PHE 68  67  67  PHE PHE E . n 
C 3 69  THR 69  68  68  THR THR E . n 
C 3 70  ILE 70  69  69  ILE ILE E . n 
C 3 71  SER 71  70  70  SER SER E . n 
C 3 72  ARG 72  71  71  ARG ARG E . n 
C 3 73  ASP 73  72  72  ASP ASP E . n 
C 3 74  ASP 74  73  73  ASP ASP E . n 
C 3 75  PRO 75  74  74  PRO PRO E . n 
C 3 76  LYS 76  75  75  LYS LYS E . n 
C 3 77  ASN 77  76  76  ASN ASN E . n 
C 3 78  THR 78  77  77  THR THR E . n 
C 3 79  LEU 79  78  78  LEU LEU E . n 
C 3 80  PHE 80  79  79  PHE PHE E . n 
C 3 81  LEU 81  80  80  LEU LEU E . n 
C 3 82  GLN 82  81  81  GLN GLN E . n 
C 3 83  MET 83  82  82  MET MET E . n 
C 3 84  THR 84  83  83  THR THR E . n 
C 3 85  SER 85  84  84  SER SER E . n 
C 3 86  LEU 86  85  85  LEU LEU E . n 
C 3 87  ARG 87  86  86  ARG ARG E . n 
C 3 88  SER 88  87  87  SER SER E . n 
C 3 89  GLU 89  88  88  GLU GLU E . n 
C 3 90  ASP 90  89  89  ASP ASP E . n 
C 3 91  THR 91  90  90  THR THR E . n 
C 3 92  ALA 92  91  91  ALA ALA E . n 
C 3 93  MET 93  92  92  MET MET E . n 
C 3 94  TYR 94  93  93  TYR TYR E . n 
C 3 95  TYR 95  94  94  TYR TYR E . n 
C 3 96  CYS 96  95  95  CYS CYS E . n 
C 3 97  VAL 97  96  96  VAL VAL E . n 
C 3 98  ARG 98  97  97  ARG ARG E . n 
C 3 99  SER 99  98  98  SER SER E . n 
C 3 100 ILE 100 99  99  ILE ILE E . n 
C 3 101 TYR 101 100 100 TYR TYR E . n 
C 3 102 TYR 102 101 101 TYR TYR E . n 
C 3 103 TYR 103 102 102 TYR TYR E . n 
C 3 104 GLY 104 103 103 GLY GLY E . n 
C 3 105 SER 105 104 104 SER SER E . n 
C 3 106 SER 106 105 105 SER SER E . n 
C 3 107 PRO 107 106 106 PRO PRO E . n 
C 3 108 PHE 108 107 107 PHE PHE E . n 
C 3 109 ASP 109 108 108 ASP ASP E . n 
C 3 110 PHE 110 109 109 PHE PHE E . n 
C 3 111 TRP 111 110 110 TRP TRP E . n 
C 3 112 GLY 112 111 111 GLY GLY E . n 
C 3 113 GLN 113 112 112 GLN GLN E . n 
C 3 114 GLY 114 113 113 GLY GLY E . n 
C 3 115 THR 115 114 114 THR THR E . n 
C 3 116 THR 116 115 115 THR THR E . n 
C 3 117 LEU 117 116 116 LEU LEU E . n 
C 3 118 THR 118 117 117 THR THR E . n 
C 3 119 VAL 119 118 118 VAL VAL E . n 
C 3 120 SER 120 119 119 SER SER E . n 
C 3 121 ALA 121 120 ?   ?   ?   E . n 
C 3 122 GLY 122 121 ?   ?   ?   E . n 
C 3 123 GLY 123 122 ?   ?   ?   E . n 
C 3 124 GLY 124 123 ?   ?   ?   E . n 
C 3 125 GLY 125 124 ?   ?   ?   E . n 
C 3 126 SER 126 125 ?   ?   ?   E . n 
C 3 127 GLY 127 126 ?   ?   ?   E . n 
C 3 128 GLY 128 127 ?   ?   ?   E . n 
C 3 129 GLY 129 128 ?   ?   ?   E . n 
C 3 130 GLY 130 129 ?   ?   ?   E . n 
C 3 131 SER 131 130 ?   ?   ?   E . n 
C 3 132 GLY 132 131 ?   ?   ?   E . n 
C 3 133 GLY 133 132 ?   ?   ?   E . n 
C 3 134 GLY 134 133 ?   ?   ?   E . n 
C 3 135 GLY 135 134 ?   ?   ?   E . n 
C 3 136 SER 136 135 ?   ?   ?   E . n 
C 3 137 ALA 137 136 136 ALA ALA E . n 
C 3 138 ASP 138 137 137 ASP ASP E . n 
C 3 139 ILE 139 138 138 ILE ILE E . n 
C 3 140 VAL 140 139 139 VAL VAL E . n 
C 3 141 MET 141 140 140 MET MET E . n 
C 3 142 THR 142 141 141 THR THR E . n 
C 3 143 GLN 143 142 142 GLN GLN E . n 
C 3 144 ALA 144 143 143 ALA ALA E . n 
C 3 145 THR 145 144 144 THR THR E . n 
C 3 146 SER 146 145 145 SER SER E . n 
C 3 147 SER 147 146 146 SER SER E . n 
C 3 148 VAL 148 147 147 VAL VAL E . n 
C 3 149 PRO 149 148 148 PRO PRO E . n 
C 3 150 VAL 150 149 149 VAL VAL E . n 
C 3 151 THR 151 150 150 THR THR E . n 
C 3 152 PRO 152 151 151 PRO PRO E . n 
C 3 153 GLY 153 152 152 GLY GLY E . n 
C 3 154 GLU 154 153 153 GLU GLU E . n 
C 3 155 SER 155 154 154 SER SER E . n 
C 3 156 VAL 156 155 155 VAL VAL E . n 
C 3 157 SER 157 156 156 SER SER E . n 
C 3 158 ILE 158 157 157 ILE ILE E . n 
C 3 159 SER 159 158 158 SER SER E . n 
C 3 160 CYS 160 159 159 CYS CYS E . n 
C 3 161 ARG 161 160 160 ARG ARG E . n 
C 3 162 SER 162 161 161 SER SER E . n 
C 3 163 SER 163 162 162 SER SER E . n 
C 3 164 LYS 164 163 163 LYS LYS E . n 
C 3 165 SER 165 164 164 SER SER E . n 
C 3 166 LEU 166 165 165 LEU LEU E . n 
C 3 167 LEU 167 166 166 LEU LEU E . n 
C 3 168 HIS 168 167 167 HIS HIS E . n 
C 3 169 SER 169 168 168 SER SER E . n 
C 3 170 ASN 170 169 169 ASN ASN E . n 
C 3 171 GLY 171 170 170 GLY GLY E . n 
C 3 172 ASN 172 171 171 ASN ASN E . n 
C 3 173 THR 173 172 172 THR THR E . n 
C 3 174 TYR 174 173 173 TYR TYR E . n 
C 3 175 LEU 175 174 174 LEU LEU E . n 
C 3 176 TYR 176 175 175 TYR TYR E . n 
C 3 177 TRP 177 176 176 TRP TRP E . n 
C 3 178 PHE 178 177 177 PHE PHE E . n 
C 3 179 LEU 179 178 178 LEU LEU E . n 
C 3 180 GLN 180 179 179 GLN GLN E . n 
C 3 181 ARG 181 180 180 ARG ARG E . n 
C 3 182 PRO 182 181 181 PRO PRO E . n 
C 3 183 GLY 183 182 182 GLY GLY E . n 
C 3 184 GLN 184 183 183 GLN GLN E . n 
C 3 185 SER 185 184 184 SER SER E . n 
C 3 186 PRO 186 185 185 PRO PRO E . n 
C 3 187 GLN 187 186 186 GLN GLN E . n 
C 3 188 LEU 188 187 187 LEU LEU E . n 
C 3 189 LEU 189 188 188 LEU LEU E . n 
C 3 190 ILE 190 189 189 ILE ILE E . n 
C 3 191 TYR 191 190 190 TYR TYR E . n 
C 3 192 ARG 192 191 191 ARG ARG E . n 
C 3 193 MET 193 192 ?   ?   ?   E . n 
C 3 194 SER 194 193 193 SER SER E . n 
C 3 195 ASN 195 194 194 ASN ASN E . n 
C 3 196 LEU 196 195 195 LEU LEU E . n 
C 3 197 ALA 197 196 196 ALA ALA E . n 
C 3 198 SER 198 197 197 SER SER E . n 
C 3 199 GLY 199 198 198 GLY GLY E . n 
C 3 200 VAL 200 199 199 VAL VAL E . n 
C 3 201 PRO 201 200 200 PRO PRO E . n 
C 3 202 ASP 202 201 201 ASP ASP E . n 
C 3 203 ARG 203 202 202 ARG ARG E . n 
C 3 204 PHE 204 203 203 PHE PHE E . n 
C 3 205 SER 205 204 204 SER SER E . n 
C 3 206 GLY 206 205 205 GLY GLY E . n 
C 3 207 SER 207 206 206 SER SER E . n 
C 3 208 GLY 208 207 207 GLY GLY E . n 
C 3 209 SER 209 208 208 SER SER E . n 
C 3 210 GLY 210 209 209 GLY GLY E . n 
C 3 211 THR 211 210 210 THR THR E . n 
C 3 212 ALA 212 211 211 ALA ALA E . n 
C 3 213 PHE 213 212 212 PHE PHE E . n 
C 3 214 THR 214 213 213 THR THR E . n 
C 3 215 LEU 215 214 214 LEU LEU E . n 
C 3 216 THR 216 215 215 THR THR E . n 
C 3 217 ILE 217 216 216 ILE ILE E . n 
C 3 218 SER 218 217 217 SER SER E . n 
C 3 219 ARG 219 218 218 ARG ARG E . n 
C 3 220 LEU 220 219 219 LEU LEU E . n 
C 3 221 GLU 221 220 220 GLU GLU E . n 
C 3 222 ALA 222 221 221 ALA ALA E . n 
C 3 223 GLU 223 222 222 GLU GLU E . n 
C 3 224 ASP 224 223 223 ASP ASP E . n 
C 3 225 VAL 225 224 224 VAL VAL E . n 
C 3 226 GLY 226 225 225 GLY GLY E . n 
C 3 227 VAL 227 226 226 VAL VAL E . n 
C 3 228 TYR 228 227 227 TYR TYR E . n 
C 3 229 TYR 229 228 228 TYR TYR E . n 
C 3 230 CYS 230 229 229 CYS CYS E . n 
C 3 231 MET 231 230 230 MET MET E . n 
C 3 232 GLN 232 231 231 GLN GLN E . n 
C 3 233 HIS 233 232 232 HIS HIS E . n 
C 3 234 LEU 234 233 233 LEU LEU E . n 
C 3 235 GLU 235 234 234 GLU GLU E . n 
C 3 236 TYR 236 235 235 TYR TYR E . n 
C 3 237 PRO 237 236 236 PRO PRO E . n 
C 3 238 LEU 238 237 237 LEU LEU E . n 
C 3 239 THR 239 238 238 THR THR E . n 
C 3 240 PHE 240 239 239 PHE PHE E . n 
C 3 241 GLY 241 240 240 GLY GLY E . n 
C 3 242 ALA 242 241 241 ALA ALA E . n 
C 3 243 GLY 243 242 242 GLY GLY E . n 
C 3 244 THR 244 243 243 THR THR E . n 
C 3 245 LYS 245 244 244 LYS LYS E . n 
C 3 246 LEU 246 245 245 LEU LEU E . n 
C 3 247 GLU 247 246 246 GLU GLU E . n 
C 3 248 LEU 248 247 247 LEU LEU E . n 
D 4 1   MET 1   0   ?   ?   ?   G . n 
D 4 2   ALA 2   1   ?   ?   ?   G . n 
D 4 3   SER 3   2   ?   ?   ?   G . n 
D 4 4   ASN 4   3   ?   ?   ?   G . n 
D 4 5   ASN 5   4   ?   ?   ?   G . n 
D 4 6   THR 6   5   5   THR THR G . n 
D 4 7   ALA 7   6   6   ALA ALA G . n 
D 4 8   SER 8   7   7   SER SER G . n 
D 4 9   ILE 9   8   8   ILE ILE G . n 
D 4 10  ALA 10  9   9   ALA ALA G . n 
D 4 11  GLN 11  10  10  GLN GLN G . n 
D 4 12  ALA 12  11  11  ALA ALA G . n 
D 4 13  ARG 13  12  12  ARG ARG G . n 
D 4 14  LYS 14  13  13  LYS LYS G . n 
D 4 15  LEU 15  14  14  LEU LEU G . n 
D 4 16  VAL 16  15  15  VAL VAL G . n 
D 4 17  GLU 17  16  16  GLU GLU G . n 
D 4 18  GLN 18  17  17  GLN GLN G . n 
D 4 19  LEU 19  18  18  LEU LEU G . n 
D 4 20  LYS 20  19  19  LYS LYS G . n 
D 4 21  MET 21  20  20  MET MET G . n 
D 4 22  GLU 22  21  21  GLU GLU G . n 
D 4 23  ALA 23  22  22  ALA ALA G . n 
D 4 24  ASN 24  23  23  ASN ASN G . n 
D 4 25  ILE 25  24  24  ILE ILE G . n 
D 4 26  ASP 26  25  25  ASP ASP G . n 
D 4 27  ARG 27  26  26  ARG ARG G . n 
D 4 28  ILE 28  27  27  ILE ILE G . n 
D 4 29  LYS 29  28  28  LYS LYS G . n 
D 4 30  VAL 30  29  29  VAL VAL G . n 
D 4 31  SER 31  30  30  SER SER G . n 
D 4 32  LYS 32  31  31  LYS LYS G . n 
D 4 33  ALA 33  32  32  ALA ALA G . n 
D 4 34  ALA 34  33  33  ALA ALA G . n 
D 4 35  ALA 35  34  34  ALA ALA G . n 
D 4 36  ASP 36  35  35  ASP ASP G . n 
D 4 37  LEU 37  36  36  LEU LEU G . n 
D 4 38  MET 38  37  37  MET MET G . n 
D 4 39  ALA 39  38  38  ALA ALA G . n 
D 4 40  TYR 40  39  39  TYR TYR G . n 
D 4 41  CYS 41  40  40  CYS CYS G . n 
D 4 42  GLU 42  41  41  GLU GLU G . n 
D 4 43  ALA 43  42  42  ALA ALA G . n 
D 4 44  HIS 44  43  43  HIS HIS G . n 
D 4 45  ALA 45  44  44  ALA ALA G . n 
D 4 46  LYS 46  45  45  LYS LYS G . n 
D 4 47  GLU 47  46  46  GLU GLU G . n 
D 4 48  ASP 48  47  47  ASP ASP G . n 
D 4 49  PRO 49  48  48  PRO PRO G . n 
D 4 50  LEU 50  49  49  LEU LEU G . n 
D 4 51  LEU 51  50  50  LEU LEU G . n 
D 4 52  THR 52  51  51  THR THR G . n 
D 4 53  PRO 53  52  52  PRO PRO G . n 
D 4 54  VAL 54  53  53  VAL VAL G . n 
D 4 55  PRO 55  54  54  PRO PRO G . n 
D 4 56  ALA 56  55  55  ALA ALA G . n 
D 4 57  SER 57  56  56  SER SER G . n 
D 4 58  GLU 58  57  57  GLU GLU G . n 
D 4 59  ASN 59  58  58  ASN ASN G . n 
D 4 60  PRO 60  59  ?   ?   ?   G . n 
D 4 61  PHE 61  60  ?   ?   ?   G . n 
D 4 62  ARG 62  61  ?   ?   ?   G . n 
D 4 63  GLU 63  62  ?   ?   ?   G . n 
D 4 64  LYS 64  63  ?   ?   ?   G . n 
D 4 65  LYS 65  64  ?   ?   ?   G . n 
D 4 66  PHE 66  65  ?   ?   ?   G . n 
D 4 67  PHE 67  66  ?   ?   ?   G . n 
D 4 68  CYS 68  67  ?   ?   ?   G . n 
D 4 69  ALA 69  68  ?   ?   ?   G . n 
D 4 70  ILE 70  69  ?   ?   ?   G . n 
D 4 71  LEU 71  70  ?   ?   ?   G . n 
E 5 1   MET 1   1   ?   ?   ?   R . n 
E 5 2   GLU 2   2   ?   ?   ?   R . n 
E 5 3   ARG 3   3   ?   ?   ?   R . n 
E 5 4   LYS 4   4   ?   ?   ?   R . n 
E 5 5   PHE 5   5   ?   ?   ?   R . n 
E 5 6   MET 6   6   ?   ?   ?   R . n 
E 5 7   SER 7   7   ?   ?   ?   R . n 
E 5 8   LEU 8   8   ?   ?   ?   R . n 
E 5 9   GLN 9   9   ?   ?   ?   R . n 
E 5 10  PRO 10  10  ?   ?   ?   R . n 
E 5 11  SER 11  11  ?   ?   ?   R . n 
E 5 12  ILE 12  12  ?   ?   ?   R . n 
E 5 13  SER 13  13  ?   ?   ?   R . n 
E 5 14  VAL 14  14  ?   ?   ?   R . n 
E 5 15  SER 15  15  ?   ?   ?   R . n 
E 5 16  GLU 16  16  ?   ?   ?   R . n 
E 5 17  MET 17  17  ?   ?   ?   R . n 
E 5 18  GLU 18  18  ?   ?   ?   R . n 
E 5 19  PRO 19  19  ?   ?   ?   R . n 
E 5 20  ASN 20  20  ?   ?   ?   R . n 
E 5 21  GLY 21  21  ?   ?   ?   R . n 
E 5 22  THR 22  22  ?   ?   ?   R . n 
E 5 23  PHE 23  23  ?   ?   ?   R . n 
E 5 24  SER 24  24  ?   ?   ?   R . n 
E 5 25  ASN 25  25  ?   ?   ?   R . n 
E 5 26  ASN 26  26  ?   ?   ?   R . n 
E 5 27  ASN 27  27  ?   ?   ?   R . n 
E 5 28  SER 28  28  ?   ?   ?   R . n 
E 5 29  ARG 29  29  ?   ?   ?   R . n 
E 5 30  ASN 30  30  ?   ?   ?   R . n 
E 5 31  CYS 31  31  ?   ?   ?   R . n 
E 5 32  THR 32  32  32  THR THR R . n 
E 5 33  ILE 33  33  33  ILE ILE R . n 
E 5 34  GLU 34  34  34  GLU GLU R . n 
E 5 35  ASN 35  35  35  ASN ASN R . n 
E 5 36  PHE 36  36  36  PHE PHE R . n 
E 5 37  LYS 37  37  37  LYS LYS R . n 
E 5 38  ARG 38  38  38  ARG ARG R . n 
E 5 39  GLU 39  39  39  GLU GLU R . n 
E 5 40  PHE 40  40  40  PHE PHE R . n 
E 5 41  PHE 41  41  41  PHE PHE R . n 
E 5 42  PRO 42  42  42  PRO PRO R . n 
E 5 43  ILE 43  43  43  ILE ILE R . n 
E 5 44  VAL 44  44  44  VAL VAL R . n 
E 5 45  TYR 45  45  45  TYR TYR R . n 
E 5 46  LEU 46  46  46  LEU LEU R . n 
E 5 47  ILE 47  47  47  ILE ILE R . n 
E 5 48  ILE 48  48  48  ILE ILE R . n 
E 5 49  PHE 49  49  49  PHE PHE R . n 
E 5 50  PHE 50  50  50  PHE PHE R . n 
E 5 51  TRP 51  51  51  TRP TRP R . n 
E 5 52  GLY 52  52  52  GLY GLY R . n 
E 5 53  VAL 53  53  53  VAL VAL R . n 
E 5 54  LEU 54  54  54  LEU LEU R . n 
E 5 55  GLY 55  55  55  GLY GLY R . n 
E 5 56  ASN 56  56  56  ASN ASN R . n 
E 5 57  GLY 57  57  57  GLY GLY R . n 
E 5 58  LEU 58  58  58  LEU LEU R . n 
E 5 59  SER 59  59  59  SER SER R . n 
E 5 60  ILE 60  60  60  ILE ILE R . n 
E 5 61  TYR 61  61  61  TYR TYR R . n 
E 5 62  VAL 62  62  62  VAL VAL R . n 
E 5 63  PHE 63  63  63  PHE PHE R . n 
E 5 64  LEU 64  64  64  LEU LEU R . n 
E 5 65  GLN 65  65  65  GLN GLN R . n 
E 5 66  PRO 66  66  66  PRO PRO R . n 
E 5 67  TYR 67  67  67  TYR TYR R . n 
E 5 68  LYS 68  68  68  LYS LYS R . n 
E 5 69  LYS 69  69  69  LYS LYS R . n 
E 5 70  SER 70  70  70  SER SER R . n 
E 5 71  THR 71  71  71  THR THR R . n 
E 5 72  SER 72  72  72  SER SER R . n 
E 5 73  VAL 73  73  73  VAL VAL R . n 
E 5 74  ASN 74  74  74  ASN ASN R . n 
E 5 75  VAL 75  75  75  VAL VAL R . n 
E 5 76  PHE 76  76  76  PHE PHE R . n 
E 5 77  MET 77  77  77  MET MET R . n 
E 5 78  LEU 78  78  78  LEU LEU R . n 
E 5 79  ASN 79  79  79  ASN ASN R . n 
E 5 80  LEU 80  80  80  LEU LEU R . n 
E 5 81  ALA 81  81  81  ALA ALA R . n 
E 5 82  ILE 82  82  82  ILE ILE R . n 
E 5 83  SER 83  83  83  SER SER R . n 
E 5 84  ASP 84  84  84  ASP ASP R . n 
E 5 85  LEU 85  85  85  LEU LEU R . n 
E 5 86  LEU 86  86  86  LEU LEU R . n 
E 5 87  PHE 87  87  87  PHE PHE R . n 
E 5 88  ILE 88  88  88  ILE ILE R . n 
E 5 89  SER 89  89  89  SER SER R . n 
E 5 90  THR 90  90  90  THR THR R . n 
E 5 91  LEU 91  91  91  LEU LEU R . n 
E 5 92  PRO 92  92  92  PRO PRO R . n 
E 5 93  PHE 93  93  93  PHE PHE R . n 
E 5 94  ARG 94  94  94  ARG ARG R . n 
E 5 95  ALA 95  95  95  ALA ALA R . n 
E 5 96  ASP 96  96  96  ASP ASP R . n 
E 5 97  TYR 97  97  97  TYR TYR R . n 
E 5 98  TYR 98  98  98  TYR TYR R . n 
E 5 99  LEU 99  99  99  LEU LEU R . n 
E 5 100 ARG 100 100 100 ARG ARG R . n 
E 5 101 GLY 101 101 101 GLY GLY R . n 
E 5 102 SER 102 102 102 SER SER R . n 
E 5 103 ASN 103 103 103 ASN ASN R . n 
E 5 104 TRP 104 104 104 TRP TRP R . n 
E 5 105 ILE 105 105 105 ILE ILE R . n 
E 5 106 PHE 106 106 106 PHE PHE R . n 
E 5 107 GLY 107 107 107 GLY GLY R . n 
E 5 108 ASP 108 108 108 ASP ASP R . n 
E 5 109 LEU 109 109 109 LEU LEU R . n 
E 5 110 ALA 110 110 110 ALA ALA R . n 
E 5 111 CYS 111 111 111 CYS CYS R . n 
E 5 112 ARG 112 112 112 ARG ARG R . n 
E 5 113 ILE 113 113 113 ILE ILE R . n 
E 5 114 MET 114 114 114 MET MET R . n 
E 5 115 SER 115 115 115 SER SER R . n 
E 5 116 TYR 116 116 116 TYR TYR R . n 
E 5 117 SER 117 117 117 SER SER R . n 
E 5 118 LEU 118 118 118 LEU LEU R . n 
E 5 119 TYR 119 119 119 TYR TYR R . n 
E 5 120 VAL 120 120 120 VAL VAL R . n 
E 5 121 ASN 121 121 121 ASN ASN R . n 
E 5 122 MET 122 122 122 MET MET R . n 
E 5 123 TYR 123 123 123 TYR TYR R . n 
E 5 124 SER 124 124 124 SER SER R . n 
E 5 125 SER 125 125 125 SER SER R . n 
E 5 126 ILE 126 126 126 ILE ILE R . n 
E 5 127 TYR 127 127 127 TYR TYR R . n 
E 5 128 PHE 128 128 128 PHE PHE R . n 
E 5 129 LEU 129 129 129 LEU LEU R . n 
E 5 130 THR 130 130 130 THR THR R . n 
E 5 131 VAL 131 131 131 VAL VAL R . n 
E 5 132 LEU 132 132 132 LEU LEU R . n 
E 5 133 SER 133 133 133 SER SER R . n 
E 5 134 VAL 134 134 134 VAL VAL R . n 
E 5 135 VAL 135 135 135 VAL VAL R . n 
E 5 136 ARG 136 136 136 ARG ARG R . n 
E 5 137 PHE 137 137 137 PHE PHE R . n 
E 5 138 LEU 138 138 138 LEU LEU R . n 
E 5 139 ALA 139 139 139 ALA ALA R . n 
E 5 140 MET 140 140 140 MET MET R . n 
E 5 141 VAL 141 141 141 VAL VAL R . n 
E 5 142 HIS 142 142 142 HIS HIS R . n 
E 5 143 PRO 143 143 143 PRO PRO R . n 
E 5 144 PHE 144 144 144 PHE PHE R . n 
E 5 145 ARG 145 145 145 ARG ARG R . n 
E 5 146 LEU 146 146 146 LEU LEU R . n 
E 5 147 LEU 147 147 147 LEU LEU R . n 
E 5 148 HIS 148 148 148 HIS HIS R . n 
E 5 149 VAL 149 149 149 VAL VAL R . n 
E 5 150 THR 150 150 150 THR THR R . n 
E 5 151 SER 151 151 151 SER SER R . n 
E 5 152 ILE 152 152 152 ILE ILE R . n 
E 5 153 ARG 153 153 153 ARG ARG R . n 
E 5 154 SER 154 154 154 SER SER R . n 
E 5 155 ALA 155 155 155 ALA ALA R . n 
E 5 156 TRP 156 156 156 TRP TRP R . n 
E 5 157 ILE 157 157 157 ILE ILE R . n 
E 5 158 LEU 158 158 158 LEU LEU R . n 
E 5 159 CYS 159 159 159 CYS CYS R . n 
E 5 160 GLY 160 160 160 GLY GLY R . n 
E 5 161 ILE 161 161 161 ILE ILE R . n 
E 5 162 ILE 162 162 162 ILE ILE R . n 
E 5 163 TRP 163 163 163 TRP TRP R . n 
E 5 164 ILE 164 164 164 ILE ILE R . n 
E 5 165 LEU 165 165 165 LEU LEU R . n 
E 5 166 ILE 166 166 166 ILE ILE R . n 
E 5 167 MET 167 167 167 MET MET R . n 
E 5 168 ALA 168 168 168 ALA ALA R . n 
E 5 169 SER 169 169 169 SER SER R . n 
E 5 170 SER 170 170 170 SER SER R . n 
E 5 171 ILE 171 171 171 ILE ILE R . n 
E 5 172 MET 172 172 172 MET MET R . n 
E 5 173 LEU 173 173 173 LEU LEU R . n 
E 5 174 LEU 174 174 174 LEU LEU R . n 
E 5 175 ASP 175 175 175 ASP ASP R . n 
E 5 176 SER 176 176 176 SER SER R . n 
E 5 177 GLY 177 177 177 GLY GLY R . n 
E 5 178 SER 178 178 178 SER SER R . n 
E 5 179 GLU 179 179 179 GLU GLU R . n 
E 5 180 GLN 180 180 180 GLN GLN R . n 
E 5 181 ASN 181 181 181 ASN ASN R . n 
E 5 182 GLY 182 182 182 GLY GLY R . n 
E 5 183 SER 183 183 183 SER SER R . n 
E 5 184 VAL 184 184 184 VAL VAL R . n 
E 5 185 THR 185 185 185 THR THR R . n 
E 5 186 SER 186 186 186 SER SER R . n 
E 5 187 CYS 187 187 187 CYS CYS R . n 
E 5 188 LEU 188 188 188 LEU LEU R . n 
E 5 189 GLU 189 189 189 GLU GLU R . n 
E 5 190 LEU 190 190 190 LEU LEU R . n 
E 5 191 ASN 191 191 191 ASN ASN R . n 
E 5 192 LEU 192 192 192 LEU LEU R . n 
E 5 193 TYR 193 193 193 TYR TYR R . n 
E 5 194 LYS 194 194 194 LYS LYS R . n 
E 5 195 ILE 195 195 195 ILE ILE R . n 
E 5 196 ALA 196 196 196 ALA ALA R . n 
E 5 197 LYS 197 197 197 LYS LYS R . n 
E 5 198 LEU 198 198 198 LEU LEU R . n 
E 5 199 GLN 199 199 199 GLN GLN R . n 
E 5 200 THR 200 200 200 THR THR R . n 
E 5 201 MET 201 201 201 MET MET R . n 
E 5 202 ASN 202 202 202 ASN ASN R . n 
E 5 203 TYR 203 203 203 TYR TYR R . n 
E 5 204 ILE 204 204 204 ILE ILE R . n 
E 5 205 ALA 205 205 205 ALA ALA R . n 
E 5 206 LEU 206 206 206 LEU LEU R . n 
E 5 207 VAL 207 207 207 VAL VAL R . n 
E 5 208 VAL 208 208 208 VAL VAL R . n 
E 5 209 GLY 209 209 209 GLY GLY R . n 
E 5 210 CYS 210 210 210 CYS CYS R . n 
E 5 211 LEU 211 211 211 LEU LEU R . n 
E 5 212 LEU 212 212 212 LEU LEU R . n 
E 5 213 PRO 213 213 213 PRO PRO R . n 
E 5 214 PHE 214 214 214 PHE PHE R . n 
E 5 215 PHE 215 215 215 PHE PHE R . n 
E 5 216 THR 216 216 216 THR THR R . n 
E 5 217 LEU 217 217 217 LEU LEU R . n 
E 5 218 SER 218 218 218 SER SER R . n 
E 5 219 ILE 219 219 219 ILE ILE R . n 
E 5 220 CYS 220 220 220 CYS CYS R . n 
E 5 221 TYR 221 221 221 TYR TYR R . n 
E 5 222 LEU 222 222 222 LEU LEU R . n 
E 5 223 LEU 223 223 223 LEU LEU R . n 
E 5 224 ILE 224 224 224 ILE ILE R . n 
E 5 225 ILE 225 225 225 ILE ILE R . n 
E 5 226 ARG 226 226 226 ARG ARG R . n 
E 5 227 VAL 227 227 227 VAL VAL R . n 
E 5 228 LEU 228 228 228 LEU LEU R . n 
E 5 229 LEU 229 229 229 LEU LEU R . n 
E 5 230 LYS 230 230 230 LYS LYS R . n 
E 5 231 VAL 231 231 231 VAL VAL R . n 
E 5 232 GLU 232 232 232 GLU GLU R . n 
E 5 233 VAL 233 233 233 VAL VAL R . n 
E 5 234 PRO 234 234 ?   ?   ?   R . n 
E 5 235 GLU 235 235 ?   ?   ?   R . n 
E 5 236 SER 236 236 ?   ?   ?   R . n 
E 5 237 GLY 237 237 ?   ?   ?   R . n 
E 5 238 LEU 238 238 ?   ?   ?   R . n 
E 5 239 ARG 239 239 239 ARG ARG R . n 
E 5 240 VAL 240 240 240 VAL VAL R . n 
E 5 241 SER 241 241 241 SER SER R . n 
E 5 242 HIS 242 242 242 HIS HIS R . n 
E 5 243 ARG 243 243 243 ARG ARG R . n 
E 5 244 LYS 244 244 244 LYS LYS R . n 
E 5 245 ALA 245 245 245 ALA ALA R . n 
E 5 246 LEU 246 246 246 LEU LEU R . n 
E 5 247 THR 247 247 247 THR THR R . n 
E 5 248 THR 248 248 248 THR THR R . n 
E 5 249 ILE 249 249 249 ILE ILE R . n 
E 5 250 ILE 250 250 250 ILE ILE R . n 
E 5 251 ILE 251 251 251 ILE ILE R . n 
E 5 252 THR 252 252 252 THR THR R . n 
E 5 253 LEU 253 253 253 LEU LEU R . n 
E 5 254 ILE 254 254 254 ILE ILE R . n 
E 5 255 ILE 255 255 255 ILE ILE R . n 
E 5 256 PHE 256 256 256 PHE PHE R . n 
E 5 257 PHE 257 257 257 PHE PHE R . n 
E 5 258 LEU 258 258 258 LEU LEU R . n 
E 5 259 CYS 259 259 259 CYS CYS R . n 
E 5 260 PHE 260 260 260 PHE PHE R . n 
E 5 261 LEU 261 261 261 LEU LEU R . n 
E 5 262 PRO 262 262 262 PRO PRO R . n 
E 5 263 TYR 263 263 263 TYR TYR R . n 
E 5 264 HIS 264 264 264 HIS HIS R . n 
E 5 265 THR 265 265 265 THR THR R . n 
E 5 266 LEU 266 266 266 LEU LEU R . n 
E 5 267 ARG 267 267 267 ARG ARG R . n 
E 5 268 THR 268 268 268 THR THR R . n 
E 5 269 VAL 269 269 269 VAL VAL R . n 
E 5 270 HIS 270 270 270 HIS HIS R . n 
E 5 271 LEU 271 271 271 LEU LEU R . n 
E 5 272 THR 272 272 272 THR THR R . n 
E 5 273 THR 273 273 273 THR THR R . n 
E 5 274 TRP 274 274 274 TRP TRP R . n 
E 5 275 LYS 275 275 275 LYS LYS R . n 
E 5 276 VAL 276 276 276 VAL VAL R . n 
E 5 277 GLY 277 277 277 GLY GLY R . n 
E 5 278 LEU 278 278 278 LEU LEU R . n 
E 5 279 CYS 279 279 279 CYS CYS R . n 
E 5 280 LYS 280 280 280 LYS LYS R . n 
E 5 281 ASP 281 281 281 ASP ASP R . n 
E 5 282 ARG 282 282 282 ARG ARG R . n 
E 5 283 LEU 283 283 283 LEU LEU R . n 
E 5 284 HIS 284 284 284 HIS HIS R . n 
E 5 285 LYS 285 285 285 LYS LYS R . n 
E 5 286 ALA 286 286 286 ALA ALA R . n 
E 5 287 LEU 287 287 287 LEU LEU R . n 
E 5 288 VAL 288 288 288 VAL VAL R . n 
E 5 289 ILE 289 289 289 ILE ILE R . n 
E 5 290 THR 290 290 290 THR THR R . n 
E 5 291 LEU 291 291 291 LEU LEU R . n 
E 5 292 ALA 292 292 292 ALA ALA R . n 
E 5 293 LEU 293 293 293 LEU LEU R . n 
E 5 294 ALA 294 294 294 ALA ALA R . n 
E 5 295 ALA 295 295 295 ALA ALA R . n 
E 5 296 ALA 296 296 296 ALA ALA R . n 
E 5 297 ASN 297 297 297 ASN ASN R . n 
E 5 298 ALA 298 298 298 ALA ALA R . n 
E 5 299 CYS 299 299 299 CYS CYS R . n 
E 5 300 PHE 300 300 300 PHE PHE R . n 
E 5 301 ASN 301 301 301 ASN ASN R . n 
E 5 302 PRO 302 302 302 PRO PRO R . n 
E 5 303 LEU 303 303 303 LEU LEU R . n 
E 5 304 LEU 304 304 304 LEU LEU R . n 
E 5 305 TYR 305 305 305 TYR TYR R . n 
E 5 306 TYR 306 306 306 TYR TYR R . n 
E 5 307 PHE 307 307 307 PHE PHE R . n 
E 5 308 ALA 308 308 308 ALA ALA R . n 
E 5 309 GLY 309 309 309 GLY GLY R . n 
E 5 310 GLU 310 310 310 GLU GLU R . n 
E 5 311 ASN 311 311 311 ASN ASN R . n 
E 5 312 PHE 312 312 312 PHE PHE R . n 
E 5 313 LYS 313 313 313 LYS LYS R . n 
E 5 314 ASP 314 314 314 ASP ASP R . n 
E 5 315 ARG 315 315 315 ARG ARG R . n 
E 5 316 LEU 316 316 316 LEU LEU R . n 
E 5 317 LYS 317 317 317 LYS LYS R . n 
E 5 318 SER 318 318 318 SER SER R . n 
E 5 319 ALA 319 319 319 ALA ALA R . n 
E 5 320 LEU 320 320 320 LEU LEU R . n 
E 5 321 ARG 321 321 321 ARG ARG R . n 
E 5 322 LYS 322 322 322 LYS LYS R . n 
E 5 323 GLY 323 323 323 GLY GLY R . n 
E 5 324 HIS 324 324 ?   ?   ?   R . n 
E 5 325 PRO 325 325 ?   ?   ?   R . n 
E 5 326 GLN 326 326 ?   ?   ?   R . n 
E 5 327 LYS 327 327 ?   ?   ?   R . n 
E 5 328 ALA 328 328 ?   ?   ?   R . n 
E 5 329 LYS 329 329 ?   ?   ?   R . n 
E 5 330 THR 330 330 ?   ?   ?   R . n 
E 5 331 LYS 331 331 ?   ?   ?   R . n 
E 5 332 CYS 332 332 ?   ?   ?   R . n 
E 5 333 VAL 333 333 ?   ?   ?   R . n 
E 5 334 PHE 334 334 ?   ?   ?   R . n 
E 5 335 PRO 335 335 ?   ?   ?   R . n 
E 5 336 VAL 336 336 ?   ?   ?   R . n 
E 5 337 SER 337 337 ?   ?   ?   R . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        LTD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   LTD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          LTD 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      LTD 
_pdbx_nonpoly_scheme.auth_mon_id     LIG 
_pdbx_nonpoly_scheme.pdb_strand_id   R 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B ASP 295 ? CG  ? B ASP 301 CG  
2 1 Y 1 B ASP 295 ? OD1 ? B ASP 301 OD1 
3 1 Y 1 B ASP 295 ? OD2 ? B ASP 301 OD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9IXX 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9IXX 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9IXX 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9IXX 
_struct.title                        'Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9IXX 
_struct_keywords.text            'GPCR, CysLT2R, LTD4, MEMBRANE PROTEIN/IMMUNE SYSTEM, MEMBRANE PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9IXX        9IXX   ? 1 ? 1 
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2 
3 PDB 9IXX        9IXX   ? 3 ? 1 
4 UNP GBG2_HUMAN  P59768 ? 4 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1 
5 UNP CLTR2_HUMAN Q9NS75 ? 5 
;MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNL
AISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCG
IIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRV
SHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLKSAL
RKGHPQKAKTKCVFPVS
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9IXX A 1  ? 361 ? 9IXX   1 ? 361 ? 1 361 
2 2 9IXX B 13 ? 351 ? P62873 2 ? 340 ? 7 345 
3 3 9IXX E 1  ? 248 ? 9IXX   0 ? 247 ? 0 247 
4 4 9IXX G 1  ? 71  ? P59768 1 ? 71  ? 0 70  
5 5 9IXX R 1  ? 337 ? Q9NS75 1 ? 337 ? 1 337 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 9IXX MET B 1  ? UNP P62873 ? ? 'initiating methionine' -5 1  
2 9IXX HIS B 2  ? UNP P62873 ? ? 'expression tag'        -4 2  
2 9IXX HIS B 3  ? UNP P62873 ? ? 'expression tag'        -3 3  
2 9IXX HIS B 4  ? UNP P62873 ? ? 'expression tag'        -2 4  
2 9IXX HIS B 5  ? UNP P62873 ? ? 'expression tag'        -1 5  
2 9IXX HIS B 6  ? UNP P62873 ? ? 'expression tag'        0  6  
2 9IXX HIS B 7  ? UNP P62873 ? ? 'expression tag'        1  7  
2 9IXX GLY B 8  ? UNP P62873 ? ? 'expression tag'        2  8  
2 9IXX SER B 9  ? UNP P62873 ? ? 'expression tag'        3  9  
2 9IXX LEU B 10 ? UNP P62873 ? ? 'expression tag'        4  10 
2 9IXX LEU B 11 ? UNP P62873 ? ? 'expression tag'        5  11 
2 9IXX GLN B 12 ? UNP P62873 ? ? 'expression tag'        6  12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? THR A 33  ? SER A 6   THR A 33  1 ? 28 
HELX_P HELX_P2  AA2 GLY A 45  ? MET A 53  ? GLY A 45  MET A 53  1 ? 9  
HELX_P HELX_P3  AA3 ILE A 212 ? ASN A 216 ? ILE A 212 ASN A 216 5 ? 5  
HELX_P HELX_P4  AA4 ARG A 232 ? ASN A 245 ? ARG A 232 ASN A 245 1 ? 14 
HELX_P HELX_P5  AA5 TRP A 248 ? ILE A 252 ? TRP A 248 ILE A 252 5 ? 5  
HELX_P HELX_P6  AA6 LYS A 260 ? GLY A 271 ? LYS A 260 GLY A 271 1 ? 12 
HELX_P HELX_P7  AA7 LYS A 274 ? TYR A 278 ? LYS A 274 TYR A 278 5 ? 5  
HELX_P HELX_P8  AA8 PHE A 279 ? TYR A 285 ? PHE A 279 TYR A 285 5 ? 7  
HELX_P HELX_P9  AA9 ASP A 298 ? ALA A 318 ? ASP A 298 ALA A 318 1 ? 21 
HELX_P HELX_P10 AB1 ASN A 338 ? TYR A 358 ? ASN A 338 TYR A 358 1 ? 21 
HELX_P HELX_P11 AB2 LEU B 15  ? CYS B 36  ? LEU B 9   CYS B 30  1 ? 22 
HELX_P HELX_P12 AB3 THR B 40  ? THR B 45  ? THR B 34  THR B 39  1 ? 6  
HELX_P HELX_P13 AB4 SER C 53  ? GLY C 56  ? SER E 52  GLY E 55  5 ? 4  
HELX_P HELX_P14 AB5 ARG C 87  ? THR C 91  ? ARG E 86  THR E 90  5 ? 5  
HELX_P HELX_P15 AB6 ALA D 7   ? ASN D 24  ? ALA G 6   ASN G 23  1 ? 18 
HELX_P HELX_P16 AB7 LYS D 29  ? HIS D 44  ? LYS G 28  HIS G 43  1 ? 16 
HELX_P HELX_P17 AB8 ILE E 33  ? LEU E 64  ? ILE R 33  LEU R 64  1 ? 32 
HELX_P HELX_P18 AB9 THR E 71  ? THR E 90  ? THR R 71  THR R 90  1 ? 20 
HELX_P HELX_P19 AC1 THR E 90  ? ARG E 100 ? THR R 90  ARG R 100 1 ? 11 
HELX_P HELX_P20 AC2 GLY E 107 ? HIS E 142 ? GLY R 107 HIS R 142 1 ? 36 
HELX_P HELX_P21 AC3 ILE E 152 ? ILE E 171 ? ILE R 152 ILE R 171 1 ? 20 
HELX_P HELX_P22 AC4 MET E 172 ? SER E 176 ? MET R 172 SER R 176 5 ? 5  
HELX_P HELX_P23 AC5 ASN E 191 ? TYR E 193 ? ASN R 191 TYR R 193 5 ? 3  
HELX_P HELX_P24 AC6 LYS E 194 ? GLY E 209 ? LYS R 194 GLY R 209 1 ? 16 
HELX_P HELX_P25 AC7 CYS E 210 ? LEU E 229 ? CYS R 210 LEU R 229 1 ? 20 
HELX_P HELX_P26 AC8 VAL E 240 ? LEU E 258 ? VAL R 240 LEU R 258 1 ? 19 
HELX_P HELX_P27 AC9 PHE E 260 ? THR E 272 ? PHE R 260 THR R 272 1 ? 13 
HELX_P HELX_P28 AD1 ARG E 282 ? ALA E 296 ? ARG R 282 ALA R 296 1 ? 15 
HELX_P HELX_P29 AD2 ALA E 296 ? TYR E 306 ? ALA R 296 TYR R 306 1 ? 11 
HELX_P HELX_P30 AD3 GLY E 309 ? ARG E 321 ? GLY R 309 ARG R 321 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           E 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            111 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           E 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            187 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            R 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             111 
_struct_conn.ptnr2_auth_asym_id            R 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             187 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.027 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      E 
_pdbx_modification_feature.label_seq_id                       111 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     E 
_pdbx_modification_feature.modified_residue_label_seq_id      187 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       R 
_pdbx_modification_feature.auth_seq_id                        111 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      R 
_pdbx_modification_feature.modified_residue_auth_seq_id       187 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 5 ? 
AB5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE A 185 ? VAL A 191 ? PHE A 185 VAL A 191 
AA1 2 VAL A 194 ? ASP A 200 ? VAL A 194 ASP A 200 
AA1 3 ARG A 35  ? GLY A 40  ? ARG A 35  GLY A 40  
AA1 4 ALA A 220 ? VAL A 224 ? ALA A 220 VAL A 224 
AA1 5 VAL A 254 ? PHE A 257 ? VAL A 254 PHE A 257 
AA1 6 CYS A 326 ? HIS A 329 ? CYS A 326 HIS A 329 
AA2 1 ARG B 57  ? LEU B 62  ? ARG B 51  LEU B 56  
AA2 2 LEU B 347 ? ASN B 351 ? LEU B 341 ASN B 345 
AA2 3 VAL B 338 ? SER B 342 ? VAL B 332 SER B 336 
AA2 4 VAL B 326 ? VAL B 331 ? VAL B 320 VAL B 325 
AA3 1 ILE B 69  ? TRP B 74  ? ILE B 63  TRP B 68  
AA3 2 LEU B 80  ? SER B 85  ? LEU B 74  SER B 79  
AA3 3 LYS B 89  ? ASP B 94  ? LYS B 83  ASP B 88  
AA3 4 LYS B 100 ? PRO B 105 ? LYS B 94  PRO B 99  
AA4 1 VAL B 111 ? TYR B 116 ? VAL B 105 TYR B 110 
AA4 2 TYR B 122 ? GLY B 127 ? TYR B 116 GLY B 121 
AA4 3 ILE B 131 ? ASN B 136 ? ILE B 125 ASN B 130 
AA4 4 ARG B 145 ? ALA B 151 ? ARG B 139 ALA B 145 
AA5 1 LEU B 157 ? PHE B 162 ? LEU B 151 PHE B 156 
AA5 2 GLN B 167 ? SER B 172 ? GLN B 161 SER B 166 
AA5 3 CYS B 177 ? ASP B 181 ? CYS B 171 ASP B 175 
AA5 4 GLN B 187 ? THR B 190 ? GLN B 181 THR B 184 
AA6 1 VAL B 198 ? LEU B 203 ? VAL B 192 LEU B 197 
AA6 2 LEU B 209 ? ALA B 214 ? LEU B 203 ALA B 208 
AA6 3 ALA B 219 ? ASP B 223 ? ALA B 213 ASP B 217 
AA6 4 CYS B 229 ? PHE B 233 ? CYS B 223 PHE B 227 
AA7 1 ILE B 240 ? PHE B 245 ? ILE B 234 PHE B 239 
AA7 2 ALA B 251 ? SER B 256 ? ALA B 245 SER B 250 
AA7 3 THR B 260 ? ASP B 265 ? THR B 254 ASP B 259 
AA7 4 GLN B 270 ? SER B 276 ? GLN B 264 SER B 270 
AA8 1 ILE B 284 ? PHE B 289 ? ILE B 278 PHE B 283 
AA8 2 LEU B 295 ? TYR B 300 ? LEU B 289 TYR B 294 
AA8 3 ASN B 304 ? ASP B 309 ? ASN B 298 ASP B 303 
AA8 4 ARG B 315 ? LEU B 319 ? ARG B 309 LEU B 313 
AA9 1 GLN C 3   ? SER C 7   ? GLN E 2   SER E 6   
AA9 2 ARG C 18  ? SER C 25  ? ARG E 17  SER E 24  
AA9 3 THR C 78  ? MET C 83  ? THR E 77  MET E 82  
AA9 4 PHE C 68  ? ASP C 73  ? PHE E 67  ASP E 72  
AB1 1 GLY C 10  ? VAL C 12  ? GLY E 9   VAL E 11  
AB1 2 THR C 115 ? VAL C 119 ? THR E 114 VAL E 118 
AB1 3 ALA C 92  ? SER C 99  ? ALA E 91  SER E 98  
AB1 4 GLY C 33  ? GLN C 39  ? GLY E 32  GLN E 38  
AB1 5 LEU C 45  ? ILE C 51  ? LEU E 44  ILE E 50  
AB1 6 ILE C 58  ? TYR C 60  ? ILE E 57  TYR E 59  
AB2 1 GLY C 10  ? VAL C 12  ? GLY E 9   VAL E 11  
AB2 2 THR C 115 ? VAL C 119 ? THR E 114 VAL E 118 
AB2 3 ALA C 92  ? SER C 99  ? ALA E 91  SER E 98  
AB2 4 PHE C 110 ? TRP C 111 ? PHE E 109 TRP E 110 
AB3 1 MET C 141 ? THR C 142 ? MET E 140 THR E 141 
AB3 2 VAL C 156 ? SER C 162 ? VAL E 155 SER E 161 
AB3 3 ALA C 212 ? ILE C 217 ? ALA E 211 ILE E 216 
AB3 4 PHE C 204 ? GLY C 208 ? PHE E 203 GLY E 207 
AB4 1 SER C 147 ? PRO C 149 ? SER E 146 PRO E 148 
AB4 2 THR C 244 ? GLU C 247 ? THR E 243 GLU E 246 
AB4 3 GLY C 226 ? GLN C 232 ? GLY E 225 GLN E 231 
AB4 4 LEU C 175 ? GLN C 180 ? LEU E 174 GLN E 179 
AB4 5 GLN C 187 ? ILE C 190 ? GLN E 186 ILE E 189 
AB5 1 GLN E 180 ? ASN E 181 ? GLN R 180 ASN R 181 
AB5 2 VAL E 184 ? THR E 185 ? VAL R 184 THR R 185 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 191 ? N VAL A 191 O VAL A 194 ? O VAL A 194 
AA1 2 3 O PHE A 199 ? O PHE A 199 N LEU A 38  ? N LEU A 38  
AA1 3 4 N LEU A 39  ? N LEU A 39  O ILE A 222 ? O ILE A 222 
AA1 4 5 N PHE A 223 ? N PHE A 223 O ILE A 255 ? O ILE A 255 
AA1 5 6 N LEU A 256 ? N LEU A 256 O TYR A 327 ? O TYR A 327 
AA2 1 2 N ARG B 57  ? N ARG B 51  O ASN B 351 ? O ASN B 345 
AA2 2 3 O TRP B 350 ? O TRP B 344 N VAL B 338 ? N VAL B 332 
AA2 3 4 O GLY B 341 ? O GLY B 335 N CYS B 328 ? N CYS B 322 
AA3 1 2 N TYR B 70  ? N TYR B 64  O ALA B 84  ? O ALA B 78  
AA3 2 3 N LEU B 81  ? N LEU B 75  O TRP B 93  ? O TRP B 87  
AA3 3 4 N LEU B 90  ? N LEU B 84  O ILE B 104 ? O ILE B 98  
AA4 1 2 N MET B 112 ? N MET B 106 O GLY B 126 ? O GLY B 120 
AA4 2 3 N VAL B 123 ? N VAL B 117 O TYR B 135 ? O TYR B 129 
AA4 3 4 N ILE B 134 ? N ILE B 128 O ARG B 148 ? O ARG B 142 
AA5 1 2 N SER B 158 ? N SER B 152 O SER B 171 ? O SER B 165 
AA5 2 3 N ILE B 168 ? N ILE B 162 O TRP B 180 ? O TRP B 174 
AA5 3 4 N LEU B 179 ? N LEU B 173 O THR B 189 ? O THR B 183 
AA6 1 2 N MET B 199 ? N MET B 193 O GLY B 213 ? O GLY B 207 
AA6 2 3 N PHE B 210 ? N PHE B 204 O TRP B 222 ? O TRP B 216 
AA6 3 4 N LEU B 221 ? N LEU B 215 O GLN B 231 ? O GLN B 225 
AA7 1 2 N ALA B 242 ? N ALA B 236 O GLY B 255 ? O GLY B 249 
AA7 2 3 N PHE B 252 ? N PHE B 246 O PHE B 264 ? O PHE B 258 
AA7 3 4 N LEU B 263 ? N LEU B 257 O LEU B 272 ? O LEU B 266 
AA8 1 2 N SER B 288 ? N SER B 282 O LEU B 297 ? O LEU B 291 
AA8 2 3 N ALA B 298 ? N ALA B 292 O ASN B 306 ? O ASN B 300 
AA8 3 4 N CYS B 305 ? N CYS B 299 O LEU B 319 ? O LEU B 313 
AA9 1 2 N VAL C 5   ? N VAL E 4   O SER C 23  ? O SER E 22  
AA9 2 3 N ARG C 18  ? N ARG E 17  O MET C 83  ? O MET E 82  
AA9 3 4 O PHE C 80  ? O PHE E 79  N SER C 71  ? N SER E 70  
AB1 1 2 N GLY C 10  ? N GLY E 9   O THR C 118 ? O THR E 117 
AB1 2 3 O LEU C 117 ? O LEU E 116 N ALA C 92  ? N ALA E 91  
AB1 3 4 O MET C 93  ? O MET E 92  N GLN C 39  ? N GLN E 38  
AB1 4 5 N ARG C 38  ? N ARG E 37  O GLU C 46  ? O GLU E 45  
AB1 5 6 N TYR C 50  ? N TYR E 49  O TYR C 59  ? O TYR E 58  
AB2 1 2 N GLY C 10  ? N GLY E 9   O THR C 118 ? O THR E 117 
AB2 2 3 O LEU C 117 ? O LEU E 116 N ALA C 92  ? N ALA E 91  
AB2 3 4 N ARG C 98  ? N ARG E 97  O PHE C 110 ? O PHE E 109 
AB3 1 2 N THR C 142 ? N THR E 141 O ARG C 161 ? O ARG E 160 
AB3 2 3 N VAL C 156 ? N VAL E 155 O ILE C 217 ? O ILE E 216 
AB3 3 4 O THR C 214 ? O THR E 213 N SER C 207 ? N SER E 206 
AB4 1 2 N VAL C 148 ? N VAL E 147 O LYS C 245 ? O LYS E 244 
AB4 2 3 O THR C 244 ? O THR E 243 N TYR C 228 ? N TYR E 227 
AB4 3 4 O VAL C 227 ? O VAL E 226 N GLN C 180 ? N GLN E 179 
AB4 4 5 N LEU C 179 ? N LEU E 178 O GLN C 187 ? O GLN E 186 
AB5 1 2 N ASN E 181 ? N ASN R 181 O VAL E 184 ? O VAL R 184 
# 
_pdbx_entry_details.entry_id                   9IXX 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   B ILE 128 ? ? OG  B SER 141 ? ? 1.98 
2 1 CE1 R HIS 284 ? ? O31 R LTD 401 ? ? 2.04 
3 1 OG  B SER 79  ? ? OD1 B ASP 81  ? ? 2.13 
4 1 O   A ALA 41  ? ? OG  A SER 44  ? ? 2.15 
5 1 OG1 B THR 226 ? ? OE2 G GLU 21  ? ? 2.17 
6 1 OD1 A ASN 216 ? ? NZ  B LYS 62  ? ? 2.18 
7 1 NH1 E ARG 218 ? ? OE2 E GLU 220 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR B 92  ? ? 71.48   -2.02   
2  1 THR B 148 ? ? -92.61  54.39   
3  1 THR B 169 ? ? 77.10   -0.96   
4  1 SER B 232 ? ? -140.59 -156.41 
5  1 GLU E 45  ? ? -160.83 116.37  
6  1 LYS R 68  ? ? -90.93  -63.11  
7  1 HIS R 148 ? ? -90.75  53.46   
8  1 LYS R 280 ? ? 75.28   -3.90   
9  1 ASP R 281 ? ? 66.90   -5.47   
10 1 ARG R 321 ? ? -91.20  55.14   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9IXX 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9IXX 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.15 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               391827 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Structure of LTD4-CysLT2R G protein complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        9IXX 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             5000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9IXX 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9IXX 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A GLY 2   ? A GLY 2   
3   1 Y 1 A CYS 3   ? A CYS 3   
4   1 Y 1 A THR 4   ? A THR 4   
5   1 Y 1 A TYR 56  ? A TYR 56  
6   1 Y 1 A HIS 57  ? A HIS 57  
7   1 Y 1 A VAL 58  ? A VAL 58  
8   1 Y 1 A ASN 59  ? A ASN 59  
9   1 Y 1 A GLY 60  ? A GLY 60  
10  1 Y 1 A TYR 61  ? A TYR 61  
11  1 Y 1 A SER 62  ? A SER 62  
12  1 Y 1 A GLU 63  ? A GLU 63  
13  1 Y 1 A GLU 64  ? A GLU 64  
14  1 Y 1 A GLU 65  ? A GLU 65  
15  1 Y 1 A CYS 66  ? A CYS 66  
16  1 Y 1 A LYS 67  ? A LYS 67  
17  1 Y 1 A GLN 68  ? A GLN 68  
18  1 Y 1 A TYR 69  ? A TYR 69  
19  1 Y 1 A LYS 70  ? A LYS 70  
20  1 Y 1 A ALA 71  ? A ALA 71  
21  1 Y 1 A VAL 72  ? A VAL 72  
22  1 Y 1 A VAL 73  ? A VAL 73  
23  1 Y 1 A TYR 74  ? A TYR 74  
24  1 Y 1 A SER 75  ? A SER 75  
25  1 Y 1 A ASN 76  ? A ASN 76  
26  1 Y 1 A THR 77  ? A THR 77  
27  1 Y 1 A ILE 78  ? A ILE 78  
28  1 Y 1 A GLN 79  ? A GLN 79  
29  1 Y 1 A SER 80  ? A SER 80  
30  1 Y 1 A ILE 81  ? A ILE 81  
31  1 Y 1 A ILE 82  ? A ILE 82  
32  1 Y 1 A ALA 83  ? A ALA 83  
33  1 Y 1 A ILE 84  ? A ILE 84  
34  1 Y 1 A ILE 85  ? A ILE 85  
35  1 Y 1 A ARG 86  ? A ARG 86  
36  1 Y 1 A ALA 87  ? A ALA 87  
37  1 Y 1 A MET 88  ? A MET 88  
38  1 Y 1 A GLY 89  ? A GLY 89  
39  1 Y 1 A ARG 90  ? A ARG 90  
40  1 Y 1 A LEU 91  ? A LEU 91  
41  1 Y 1 A LYS 92  ? A LYS 92  
42  1 Y 1 A ILE 93  ? A ILE 93  
43  1 Y 1 A ASP 94  ? A ASP 94  
44  1 Y 1 A PHE 95  ? A PHE 95  
45  1 Y 1 A GLY 96  ? A GLY 96  
46  1 Y 1 A ASP 97  ? A ASP 97  
47  1 Y 1 A SER 98  ? A SER 98  
48  1 Y 1 A ALA 99  ? A ALA 99  
49  1 Y 1 A ARG 100 ? A ARG 100 
50  1 Y 1 A ALA 101 ? A ALA 101 
51  1 Y 1 A ASP 102 ? A ASP 102 
52  1 Y 1 A ASP 103 ? A ASP 103 
53  1 Y 1 A ALA 104 ? A ALA 104 
54  1 Y 1 A ARG 105 ? A ARG 105 
55  1 Y 1 A GLN 106 ? A GLN 106 
56  1 Y 1 A LEU 107 ? A LEU 107 
57  1 Y 1 A PHE 108 ? A PHE 108 
58  1 Y 1 A VAL 109 ? A VAL 109 
59  1 Y 1 A LEU 110 ? A LEU 110 
60  1 Y 1 A ALA 111 ? A ALA 111 
61  1 Y 1 A GLY 112 ? A GLY 112 
62  1 Y 1 A ALA 113 ? A ALA 113 
63  1 Y 1 A ALA 114 ? A ALA 114 
64  1 Y 1 A GLU 115 ? A GLU 115 
65  1 Y 1 A GLU 116 ? A GLU 116 
66  1 Y 1 A GLY 117 ? A GLY 117 
67  1 Y 1 A PHE 118 ? A PHE 118 
68  1 Y 1 A MET 119 ? A MET 119 
69  1 Y 1 A THR 120 ? A THR 120 
70  1 Y 1 A ALA 121 ? A ALA 121 
71  1 Y 1 A GLU 122 ? A GLU 122 
72  1 Y 1 A LEU 123 ? A LEU 123 
73  1 Y 1 A ALA 124 ? A ALA 124 
74  1 Y 1 A GLY 125 ? A GLY 125 
75  1 Y 1 A VAL 126 ? A VAL 126 
76  1 Y 1 A ILE 127 ? A ILE 127 
77  1 Y 1 A LYS 128 ? A LYS 128 
78  1 Y 1 A ARG 129 ? A ARG 129 
79  1 Y 1 A LEU 130 ? A LEU 130 
80  1 Y 1 A TRP 131 ? A TRP 131 
81  1 Y 1 A LYS 132 ? A LYS 132 
82  1 Y 1 A ASP 133 ? A ASP 133 
83  1 Y 1 A SER 134 ? A SER 134 
84  1 Y 1 A GLY 135 ? A GLY 135 
85  1 Y 1 A VAL 136 ? A VAL 136 
86  1 Y 1 A GLN 137 ? A GLN 137 
87  1 Y 1 A ALA 138 ? A ALA 138 
88  1 Y 1 A CYS 139 ? A CYS 139 
89  1 Y 1 A PHE 140 ? A PHE 140 
90  1 Y 1 A ASN 141 ? A ASN 141 
91  1 Y 1 A ARG 142 ? A ARG 142 
92  1 Y 1 A SER 143 ? A SER 143 
93  1 Y 1 A ARG 144 ? A ARG 144 
94  1 Y 1 A GLU 145 ? A GLU 145 
95  1 Y 1 A TYR 146 ? A TYR 146 
96  1 Y 1 A GLN 147 ? A GLN 147 
97  1 Y 1 A LEU 148 ? A LEU 148 
98  1 Y 1 A ASN 149 ? A ASN 149 
99  1 Y 1 A ASP 150 ? A ASP 150 
100 1 Y 1 A SER 151 ? A SER 151 
101 1 Y 1 A ALA 152 ? A ALA 152 
102 1 Y 1 A ALA 153 ? A ALA 153 
103 1 Y 1 A TYR 154 ? A TYR 154 
104 1 Y 1 A TYR 155 ? A TYR 155 
105 1 Y 1 A LEU 156 ? A LEU 156 
106 1 Y 1 A ASN 157 ? A ASN 157 
107 1 Y 1 A ASP 158 ? A ASP 158 
108 1 Y 1 A LEU 159 ? A LEU 159 
109 1 Y 1 A ASP 160 ? A ASP 160 
110 1 Y 1 A ARG 161 ? A ARG 161 
111 1 Y 1 A ILE 162 ? A ILE 162 
112 1 Y 1 A ALA 163 ? A ALA 163 
113 1 Y 1 A GLN 164 ? A GLN 164 
114 1 Y 1 A PRO 165 ? A PRO 165 
115 1 Y 1 A ASN 166 ? A ASN 166 
116 1 Y 1 A TYR 167 ? A TYR 167 
117 1 Y 1 A ILE 168 ? A ILE 168 
118 1 Y 1 A PRO 169 ? A PRO 169 
119 1 Y 1 A THR 170 ? A THR 170 
120 1 Y 1 A GLN 171 ? A GLN 171 
121 1 Y 1 A GLN 172 ? A GLN 172 
122 1 Y 1 A ASP 173 ? A ASP 173 
123 1 Y 1 A VAL 174 ? A VAL 174 
124 1 Y 1 A LEU 175 ? A LEU 175 
125 1 Y 1 A ARG 176 ? A ARG 176 
126 1 Y 1 A THR 177 ? A THR 177 
127 1 Y 1 A ARG 178 ? A ARG 178 
128 1 Y 1 A VAL 179 ? A VAL 179 
129 1 Y 1 A LYS 180 ? A LYS 180 
130 1 Y 1 B MET -5  ? B MET 1   
131 1 Y 1 B HIS -4  ? B HIS 2   
132 1 Y 1 B HIS -3  ? B HIS 3   
133 1 Y 1 B HIS -2  ? B HIS 4   
134 1 Y 1 B HIS -1  ? B HIS 5   
135 1 Y 1 B HIS 0   ? B HIS 6   
136 1 Y 1 B HIS 1   ? B HIS 7   
137 1 Y 1 B GLY 2   ? B GLY 8   
138 1 Y 1 B SER 3   ? B SER 9   
139 1 Y 1 B LEU 4   ? B LEU 10  
140 1 Y 1 B LEU 5   ? B LEU 11  
141 1 Y 1 B GLN 6   ? B GLN 12  
142 1 Y 1 B SER 7   ? B SER 13  
143 1 Y 1 E MET 0   ? C MET 1   
144 1 Y 1 E ALA 120 ? C ALA 121 
145 1 Y 1 E GLY 121 ? C GLY 122 
146 1 Y 1 E GLY 122 ? C GLY 123 
147 1 Y 1 E GLY 123 ? C GLY 124 
148 1 Y 1 E GLY 124 ? C GLY 125 
149 1 Y 1 E SER 125 ? C SER 126 
150 1 Y 1 E GLY 126 ? C GLY 127 
151 1 Y 1 E GLY 127 ? C GLY 128 
152 1 Y 1 E GLY 128 ? C GLY 129 
153 1 Y 1 E GLY 129 ? C GLY 130 
154 1 Y 1 E SER 130 ? C SER 131 
155 1 Y 1 E GLY 131 ? C GLY 132 
156 1 Y 1 E GLY 132 ? C GLY 133 
157 1 Y 1 E GLY 133 ? C GLY 134 
158 1 Y 1 E GLY 134 ? C GLY 135 
159 1 Y 1 E SER 135 ? C SER 136 
160 1 Y 1 E MET 192 ? C MET 193 
161 1 Y 1 G MET 0   ? D MET 1   
162 1 Y 1 G ALA 1   ? D ALA 2   
163 1 Y 1 G SER 2   ? D SER 3   
164 1 Y 1 G ASN 3   ? D ASN 4   
165 1 Y 1 G ASN 4   ? D ASN 5   
166 1 Y 1 G PRO 59  ? D PRO 60  
167 1 Y 1 G PHE 60  ? D PHE 61  
168 1 Y 1 G ARG 61  ? D ARG 62  
169 1 Y 1 G GLU 62  ? D GLU 63  
170 1 Y 1 G LYS 63  ? D LYS 64  
171 1 Y 1 G LYS 64  ? D LYS 65  
172 1 Y 1 G PHE 65  ? D PHE 66  
173 1 Y 1 G PHE 66  ? D PHE 67  
174 1 Y 1 G CYS 67  ? D CYS 68  
175 1 Y 1 G ALA 68  ? D ALA 69  
176 1 Y 1 G ILE 69  ? D ILE 70  
177 1 Y 1 G LEU 70  ? D LEU 71  
178 1 Y 1 R MET 1   ? E MET 1   
179 1 Y 1 R GLU 2   ? E GLU 2   
180 1 Y 1 R ARG 3   ? E ARG 3   
181 1 Y 1 R LYS 4   ? E LYS 4   
182 1 Y 1 R PHE 5   ? E PHE 5   
183 1 Y 1 R MET 6   ? E MET 6   
184 1 Y 1 R SER 7   ? E SER 7   
185 1 Y 1 R LEU 8   ? E LEU 8   
186 1 Y 1 R GLN 9   ? E GLN 9   
187 1 Y 1 R PRO 10  ? E PRO 10  
188 1 Y 1 R SER 11  ? E SER 11  
189 1 Y 1 R ILE 12  ? E ILE 12  
190 1 Y 1 R SER 13  ? E SER 13  
191 1 Y 1 R VAL 14  ? E VAL 14  
192 1 Y 1 R SER 15  ? E SER 15  
193 1 Y 1 R GLU 16  ? E GLU 16  
194 1 Y 1 R MET 17  ? E MET 17  
195 1 Y 1 R GLU 18  ? E GLU 18  
196 1 Y 1 R PRO 19  ? E PRO 19  
197 1 Y 1 R ASN 20  ? E ASN 20  
198 1 Y 1 R GLY 21  ? E GLY 21  
199 1 Y 1 R THR 22  ? E THR 22  
200 1 Y 1 R PHE 23  ? E PHE 23  
201 1 Y 1 R SER 24  ? E SER 24  
202 1 Y 1 R ASN 25  ? E ASN 25  
203 1 Y 1 R ASN 26  ? E ASN 26  
204 1 Y 1 R ASN 27  ? E ASN 27  
205 1 Y 1 R SER 28  ? E SER 28  
206 1 Y 1 R ARG 29  ? E ARG 29  
207 1 Y 1 R ASN 30  ? E ASN 30  
208 1 Y 1 R CYS 31  ? E CYS 31  
209 1 Y 1 R PRO 234 ? E PRO 234 
210 1 Y 1 R GLU 235 ? E GLU 235 
211 1 Y 1 R SER 236 ? E SER 236 
212 1 Y 1 R GLY 237 ? E GLY 237 
213 1 Y 1 R LEU 238 ? E LEU 238 
214 1 Y 1 R HIS 324 ? E HIS 324 
215 1 Y 1 R PRO 325 ? E PRO 325 
216 1 Y 1 R GLN 326 ? E GLN 326 
217 1 Y 1 R LYS 327 ? E LYS 327 
218 1 Y 1 R ALA 328 ? E ALA 328 
219 1 Y 1 R LYS 329 ? E LYS 329 
220 1 Y 1 R THR 330 ? E THR 330 
221 1 Y 1 R LYS 331 ? E LYS 331 
222 1 Y 1 R CYS 332 ? E CYS 332 
223 1 Y 1 R VAL 333 ? E VAL 333 
224 1 Y 1 R PHE 334 ? E PHE 334 
225 1 Y 1 R PRO 335 ? E PRO 335 
226 1 Y 1 R VAL 336 ? E VAL 336 
227 1 Y 1 R SER 337 ? E SER 337 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LTD O2   O N N 202 
LTD C1   C N N 203 
LTD O1   O N N 204 
LTD C2   C N N 205 
LTD C3   C N N 206 
LTD C4   C N N 207 
LTD C5   C N S 208 
LTD O3   O N N 209 
LTD C6   C N R 210 
LTD C7   C N N 211 
LTD C8   C N N 212 
LTD C9   C N N 213 
LTD C10  C N N 214 
LTD C11  C N N 215 
LTD C12  C N N 216 
LTD C13  C N N 217 
LTD C14  C N N 218 
LTD C15  C N N 219 
LTD C16  C N N 220 
LTD C17  C N N 221 
LTD C18  C N N 222 
LTD C19  C N N 223 
LTD C20  C N N 224 
LTD O32  O N N 225 
LTD C21  C N N 226 
LTD O31  O N N 227 
LTD CA3  C N N 228 
LTD N3   N N N 229 
LTD C22  C N N 230 
LTD O33  O N N 231 
LTD CA2  C N R 232 
LTD CB2  C N N 233 
LTD SG2  S N N 234 
LTD N2   N N N 235 
LTD H1   H N N 236 
LTD H2   H N N 237 
LTD H3   H N N 238 
LTD H4   H N N 239 
LTD H5   H N N 240 
LTD H6   H N N 241 
LTD H7   H N N 242 
LTD H8   H N N 243 
LTD H9   H N N 244 
LTD H10  H N N 245 
LTD H11  H N N 246 
LTD H12  H N N 247 
LTD H13  H N N 248 
LTD H14  H N N 249 
LTD H15  H N N 250 
LTD H16  H N N 251 
LTD H17  H N N 252 
LTD H18  H N N 253 
LTD H19  H N N 254 
LTD H20  H N N 255 
LTD H21  H N N 256 
LTD H22  H N N 257 
LTD H23  H N N 258 
LTD H24  H N N 259 
LTD H25  H N N 260 
LTD H26  H N N 261 
LTD H27  H N N 262 
LTD H28  H N N 263 
LTD H29  H N N 264 
LTD H30  H N N 265 
LTD H31  H N N 266 
LTD H32  H N N 267 
LTD H33  H N N 268 
LTD H34  H N N 269 
LTD H35  H N N 270 
LTD H36  H N N 271 
LTD H37  H N N 272 
LTD H38  H N N 273 
LTD H39  H N N 274 
LTD H40  H N N 275 
LYS N    N N N 276 
LYS CA   C N S 277 
LYS C    C N N 278 
LYS O    O N N 279 
LYS CB   C N N 280 
LYS CG   C N N 281 
LYS CD   C N N 282 
LYS CE   C N N 283 
LYS NZ   N N N 284 
LYS OXT  O N N 285 
LYS H    H N N 286 
LYS H2   H N N 287 
LYS HA   H N N 288 
LYS HB2  H N N 289 
LYS HB3  H N N 290 
LYS HG2  H N N 291 
LYS HG3  H N N 292 
LYS HD2  H N N 293 
LYS HD3  H N N 294 
LYS HE2  H N N 295 
LYS HE3  H N N 296 
LYS HZ1  H N N 297 
LYS HZ2  H N N 298 
LYS HZ3  H N N 299 
LYS HXT  H N N 300 
MET N    N N N 301 
MET CA   C N S 302 
MET C    C N N 303 
MET O    O N N 304 
MET CB   C N N 305 
MET CG   C N N 306 
MET SD   S N N 307 
MET CE   C N N 308 
MET OXT  O N N 309 
MET H    H N N 310 
MET H2   H N N 311 
MET HA   H N N 312 
MET HB2  H N N 313 
MET HB3  H N N 314 
MET HG2  H N N 315 
MET HG3  H N N 316 
MET HE1  H N N 317 
MET HE2  H N N 318 
MET HE3  H N N 319 
MET HXT  H N N 320 
PHE N    N N N 321 
PHE CA   C N S 322 
PHE C    C N N 323 
PHE O    O N N 324 
PHE CB   C N N 325 
PHE CG   C Y N 326 
PHE CD1  C Y N 327 
PHE CD2  C Y N 328 
PHE CE1  C Y N 329 
PHE CE2  C Y N 330 
PHE CZ   C Y N 331 
PHE OXT  O N N 332 
PHE H    H N N 333 
PHE H2   H N N 334 
PHE HA   H N N 335 
PHE HB2  H N N 336 
PHE HB3  H N N 337 
PHE HD1  H N N 338 
PHE HD2  H N N 339 
PHE HE1  H N N 340 
PHE HE2  H N N 341 
PHE HZ   H N N 342 
PHE HXT  H N N 343 
PRO N    N N N 344 
PRO CA   C N S 345 
PRO C    C N N 346 
PRO O    O N N 347 
PRO CB   C N N 348 
PRO CG   C N N 349 
PRO CD   C N N 350 
PRO OXT  O N N 351 
PRO H    H N N 352 
PRO HA   H N N 353 
PRO HB2  H N N 354 
PRO HB3  H N N 355 
PRO HG2  H N N 356 
PRO HG3  H N N 357 
PRO HD2  H N N 358 
PRO HD3  H N N 359 
PRO HXT  H N N 360 
SER N    N N N 361 
SER CA   C N S 362 
SER C    C N N 363 
SER O    O N N 364 
SER CB   C N N 365 
SER OG   O N N 366 
SER OXT  O N N 367 
SER H    H N N 368 
SER H2   H N N 369 
SER HA   H N N 370 
SER HB2  H N N 371 
SER HB3  H N N 372 
SER HG   H N N 373 
SER HXT  H N N 374 
THR N    N N N 375 
THR CA   C N S 376 
THR C    C N N 377 
THR O    O N N 378 
THR CB   C N R 379 
THR OG1  O N N 380 
THR CG2  C N N 381 
THR OXT  O N N 382 
THR H    H N N 383 
THR H2   H N N 384 
THR HA   H N N 385 
THR HB   H N N 386 
THR HG1  H N N 387 
THR HG21 H N N 388 
THR HG22 H N N 389 
THR HG23 H N N 390 
THR HXT  H N N 391 
TRP N    N N N 392 
TRP CA   C N S 393 
TRP C    C N N 394 
TRP O    O N N 395 
TRP CB   C N N 396 
TRP CG   C Y N 397 
TRP CD1  C Y N 398 
TRP CD2  C Y N 399 
TRP NE1  N Y N 400 
TRP CE2  C Y N 401 
TRP CE3  C Y N 402 
TRP CZ2  C Y N 403 
TRP CZ3  C Y N 404 
TRP CH2  C Y N 405 
TRP OXT  O N N 406 
TRP H    H N N 407 
TRP H2   H N N 408 
TRP HA   H N N 409 
TRP HB2  H N N 410 
TRP HB3  H N N 411 
TRP HD1  H N N 412 
TRP HE1  H N N 413 
TRP HE3  H N N 414 
TRP HZ2  H N N 415 
TRP HZ3  H N N 416 
TRP HH2  H N N 417 
TRP HXT  H N N 418 
TYR N    N N N 419 
TYR CA   C N S 420 
TYR C    C N N 421 
TYR O    O N N 422 
TYR CB   C N N 423 
TYR CG   C Y N 424 
TYR CD1  C Y N 425 
TYR CD2  C Y N 426 
TYR CE1  C Y N 427 
TYR CE2  C Y N 428 
TYR CZ   C Y N 429 
TYR OH   O N N 430 
TYR OXT  O N N 431 
TYR H    H N N 432 
TYR H2   H N N 433 
TYR HA   H N N 434 
TYR HB2  H N N 435 
TYR HB3  H N N 436 
TYR HD1  H N N 437 
TYR HD2  H N N 438 
TYR HE1  H N N 439 
TYR HE2  H N N 440 
TYR HH   H N N 441 
TYR HXT  H N N 442 
VAL N    N N N 443 
VAL CA   C N S 444 
VAL C    C N N 445 
VAL O    O N N 446 
VAL CB   C N N 447 
VAL CG1  C N N 448 
VAL CG2  C N N 449 
VAL OXT  O N N 450 
VAL H    H N N 451 
VAL H2   H N N 452 
VAL HA   H N N 453 
VAL HB   H N N 454 
VAL HG11 H N N 455 
VAL HG12 H N N 456 
VAL HG13 H N N 457 
VAL HG21 H N N 458 
VAL HG22 H N N 459 
VAL HG23 H N N 460 
VAL HXT  H N N 461 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LTD O32 C21  doub N N 192 
LTD C20 C19  sing N N 193 
LTD C21 O31  sing N N 194 
LTD C21 CA3  sing N N 195 
LTD C19 C18  sing N N 196 
LTD CA3 N3   sing N N 197 
LTD C18 C17  sing N N 198 
LTD C17 C16  sing N N 199 
LTD N3  C22  sing N N 200 
LTD C11 C12  doub N Z 201 
LTD C11 C10  sing N N 202 
LTD O3  C5   sing N N 203 
LTD O1  C1   doub N N 204 
LTD C12 C13  sing N N 205 
LTD O33 C22  doub N N 206 
LTD C9  C10  doub N E 207 
LTD C9  C8   sing N N 208 
LTD C22 CA2  sing N N 209 
LTD C16 C15  sing N N 210 
LTD C7  C8   doub N E 211 
LTD C7  C6   sing N N 212 
LTD C1  C2   sing N N 213 
LTD C1  O2   sing N N 214 
LTD C5  C4   sing N N 215 
LTD C5  C6   sing N N 216 
LTD SG2 C6   sing N N 217 
LTD SG2 CB2  sing N N 218 
LTD C3  C4   sing N N 219 
LTD C3  C2   sing N N 220 
LTD C13 C14  sing N N 221 
LTD C15 C14  doub N Z 222 
LTD CA2 N2   sing N N 223 
LTD CA2 CB2  sing N N 224 
LTD O2  H1   sing N N 225 
LTD C2  H2   sing N N 226 
LTD C2  H3   sing N N 227 
LTD C3  H4   sing N N 228 
LTD C3  H5   sing N N 229 
LTD C4  H6   sing N N 230 
LTD C4  H7   sing N N 231 
LTD C5  H8   sing N N 232 
LTD O3  H9   sing N N 233 
LTD C6  H10  sing N N 234 
LTD C7  H11  sing N N 235 
LTD C8  H12  sing N N 236 
LTD C9  H13  sing N N 237 
LTD C10 H14  sing N N 238 
LTD C11 H15  sing N N 239 
LTD C12 H16  sing N N 240 
LTD C13 H17  sing N N 241 
LTD C13 H18  sing N N 242 
LTD C14 H19  sing N N 243 
LTD C15 H20  sing N N 244 
LTD C16 H21  sing N N 245 
LTD C16 H22  sing N N 246 
LTD C17 H23  sing N N 247 
LTD C17 H24  sing N N 248 
LTD C18 H25  sing N N 249 
LTD C18 H26  sing N N 250 
LTD C19 H27  sing N N 251 
LTD C19 H28  sing N N 252 
LTD C20 H29  sing N N 253 
LTD C20 H30  sing N N 254 
LTD C20 H31  sing N N 255 
LTD O31 H32  sing N N 256 
LTD CA3 H33  sing N N 257 
LTD CA3 H34  sing N N 258 
LTD N3  H35  sing N N 259 
LTD CA2 H36  sing N N 260 
LTD CB2 H37  sing N N 261 
LTD CB2 H38  sing N N 262 
LTD N2  H39  sing N N 263 
LTD N2  H40  sing N N 264 
LYS N   CA   sing N N 265 
LYS N   H    sing N N 266 
LYS N   H2   sing N N 267 
LYS CA  C    sing N N 268 
LYS CA  CB   sing N N 269 
LYS CA  HA   sing N N 270 
LYS C   O    doub N N 271 
LYS C   OXT  sing N N 272 
LYS CB  CG   sing N N 273 
LYS CB  HB2  sing N N 274 
LYS CB  HB3  sing N N 275 
LYS CG  CD   sing N N 276 
LYS CG  HG2  sing N N 277 
LYS CG  HG3  sing N N 278 
LYS CD  CE   sing N N 279 
LYS CD  HD2  sing N N 280 
LYS CD  HD3  sing N N 281 
LYS CE  NZ   sing N N 282 
LYS CE  HE2  sing N N 283 
LYS CE  HE3  sing N N 284 
LYS NZ  HZ1  sing N N 285 
LYS NZ  HZ2  sing N N 286 
LYS NZ  HZ3  sing N N 287 
LYS OXT HXT  sing N N 288 
MET N   CA   sing N N 289 
MET N   H    sing N N 290 
MET N   H2   sing N N 291 
MET CA  C    sing N N 292 
MET CA  CB   sing N N 293 
MET CA  HA   sing N N 294 
MET C   O    doub N N 295 
MET C   OXT  sing N N 296 
MET CB  CG   sing N N 297 
MET CB  HB2  sing N N 298 
MET CB  HB3  sing N N 299 
MET CG  SD   sing N N 300 
MET CG  HG2  sing N N 301 
MET CG  HG3  sing N N 302 
MET SD  CE   sing N N 303 
MET CE  HE1  sing N N 304 
MET CE  HE2  sing N N 305 
MET CE  HE3  sing N N 306 
MET OXT HXT  sing N N 307 
PHE N   CA   sing N N 308 
PHE N   H    sing N N 309 
PHE N   H2   sing N N 310 
PHE CA  C    sing N N 311 
PHE CA  CB   sing N N 312 
PHE CA  HA   sing N N 313 
PHE C   O    doub N N 314 
PHE C   OXT  sing N N 315 
PHE CB  CG   sing N N 316 
PHE CB  HB2  sing N N 317 
PHE CB  HB3  sing N N 318 
PHE CG  CD1  doub Y N 319 
PHE CG  CD2  sing Y N 320 
PHE CD1 CE1  sing Y N 321 
PHE CD1 HD1  sing N N 322 
PHE CD2 CE2  doub Y N 323 
PHE CD2 HD2  sing N N 324 
PHE CE1 CZ   doub Y N 325 
PHE CE1 HE1  sing N N 326 
PHE CE2 CZ   sing Y N 327 
PHE CE2 HE2  sing N N 328 
PHE CZ  HZ   sing N N 329 
PHE OXT HXT  sing N N 330 
PRO N   CA   sing N N 331 
PRO N   CD   sing N N 332 
PRO N   H    sing N N 333 
PRO CA  C    sing N N 334 
PRO CA  CB   sing N N 335 
PRO CA  HA   sing N N 336 
PRO C   O    doub N N 337 
PRO C   OXT  sing N N 338 
PRO CB  CG   sing N N 339 
PRO CB  HB2  sing N N 340 
PRO CB  HB3  sing N N 341 
PRO CG  CD   sing N N 342 
PRO CG  HG2  sing N N 343 
PRO CG  HG3  sing N N 344 
PRO CD  HD2  sing N N 345 
PRO CD  HD3  sing N N 346 
PRO OXT HXT  sing N N 347 
SER N   CA   sing N N 348 
SER N   H    sing N N 349 
SER N   H2   sing N N 350 
SER CA  C    sing N N 351 
SER CA  CB   sing N N 352 
SER CA  HA   sing N N 353 
SER C   O    doub N N 354 
SER C   OXT  sing N N 355 
SER CB  OG   sing N N 356 
SER CB  HB2  sing N N 357 
SER CB  HB3  sing N N 358 
SER OG  HG   sing N N 359 
SER OXT HXT  sing N N 360 
THR N   CA   sing N N 361 
THR N   H    sing N N 362 
THR N   H2   sing N N 363 
THR CA  C    sing N N 364 
THR CA  CB   sing N N 365 
THR CA  HA   sing N N 366 
THR C   O    doub N N 367 
THR C   OXT  sing N N 368 
THR CB  OG1  sing N N 369 
THR CB  CG2  sing N N 370 
THR CB  HB   sing N N 371 
THR OG1 HG1  sing N N 372 
THR CG2 HG21 sing N N 373 
THR CG2 HG22 sing N N 374 
THR CG2 HG23 sing N N 375 
THR OXT HXT  sing N N 376 
TRP N   CA   sing N N 377 
TRP N   H    sing N N 378 
TRP N   H2   sing N N 379 
TRP CA  C    sing N N 380 
TRP CA  CB   sing N N 381 
TRP CA  HA   sing N N 382 
TRP C   O    doub N N 383 
TRP C   OXT  sing N N 384 
TRP CB  CG   sing N N 385 
TRP CB  HB2  sing N N 386 
TRP CB  HB3  sing N N 387 
TRP CG  CD1  doub Y N 388 
TRP CG  CD2  sing Y N 389 
TRP CD1 NE1  sing Y N 390 
TRP CD1 HD1  sing N N 391 
TRP CD2 CE2  doub Y N 392 
TRP CD2 CE3  sing Y N 393 
TRP NE1 CE2  sing Y N 394 
TRP NE1 HE1  sing N N 395 
TRP CE2 CZ2  sing Y N 396 
TRP CE3 CZ3  doub Y N 397 
TRP CE3 HE3  sing N N 398 
TRP CZ2 CH2  doub Y N 399 
TRP CZ2 HZ2  sing N N 400 
TRP CZ3 CH2  sing Y N 401 
TRP CZ3 HZ3  sing N N 402 
TRP CH2 HH2  sing N N 403 
TRP OXT HXT  sing N N 404 
TYR N   CA   sing N N 405 
TYR N   H    sing N N 406 
TYR N   H2   sing N N 407 
TYR CA  C    sing N N 408 
TYR CA  CB   sing N N 409 
TYR CA  HA   sing N N 410 
TYR C   O    doub N N 411 
TYR C   OXT  sing N N 412 
TYR CB  CG   sing N N 413 
TYR CB  HB2  sing N N 414 
TYR CB  HB3  sing N N 415 
TYR CG  CD1  doub Y N 416 
TYR CG  CD2  sing Y N 417 
TYR CD1 CE1  sing Y N 418 
TYR CD1 HD1  sing N N 419 
TYR CD2 CE2  doub Y N 420 
TYR CD2 HD2  sing N N 421 
TYR CE1 CZ   doub Y N 422 
TYR CE1 HE1  sing N N 423 
TYR CE2 CZ   sing Y N 424 
TYR CE2 HE2  sing N N 425 
TYR CZ  OH   sing N N 426 
TYR OH  HH   sing N N 427 
TYR OXT HXT  sing N N 428 
VAL N   CA   sing N N 429 
VAL N   H    sing N N 430 
VAL N   H2   sing N N 431 
VAL CA  C    sing N N 432 
VAL CA  CB   sing N N 433 
VAL CA  HA   sing N N 434 
VAL C   O    doub N N 435 
VAL C   OXT  sing N N 436 
VAL CB  CG1  sing N N 437 
VAL CB  CG2  sing N N 438 
VAL CB  HB   sing N N 439 
VAL CG1 HG11 sing N N 440 
VAL CG1 HG12 sing N N 441 
VAL CG1 HG13 sing N N 442 
VAL CG2 HG21 sing N N 443 
VAL CG2 HG22 sing N N 444 
VAL CG2 HG23 sing N N 445 
VAL OXT HXT  sing N N 446 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-29 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9IXX 
_em_admin.last_update        2025-04-30 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'Structural basis of the cysteinyl leukotriene receptor type 2 activation by LTD4' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 2 9606  'Homo sapiens'      ? ? ? ? ? 
? ? 1 3 10116 'Rattus norvegicus' ? ? ? ? ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7111 
_em_entity_assembly_recombinant.organism             'Trichoplusia ni' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9IXX 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . LEU A 1 5   ? 68.424  109.755 98.106  1.00 62.79  ?  5   LEU A N   1 
ATOM   2    C CA  . LEU A 1 5   ? 69.039  110.340 99.332  1.00 62.79  ?  5   LEU A CA  1 
ATOM   3    C C   . LEU A 1 5   ? 68.179  111.482 99.865  1.00 62.79  ?  5   LEU A C   1 
ATOM   4    O O   . LEU A 1 5   ? 67.812  112.394 99.123  1.00 62.79  ?  5   LEU A O   1 
ATOM   5    C CB  . LEU A 1 5   ? 70.456  110.836 99.034  1.00 62.79  ?  5   LEU A CB  1 
ATOM   6    C CG  . LEU A 1 5   ? 71.297  111.251 100.244 1.00 62.79  ?  5   LEU A CG  1 
ATOM   7    C CD1 . LEU A 1 5   ? 71.527  110.066 101.170 1.00 62.79  ?  5   LEU A CD1 1 
ATOM   8    C CD2 . LEU A 1 5   ? 72.622  111.846 99.794  1.00 62.79  ?  5   LEU A CD2 1 
ATOM   9    N N   . SER A 1 6   ? 67.860  111.426 101.155 1.00 62.54  ?  6   SER A N   1 
ATOM   10   C CA  . SER A 1 6   ? 67.006  112.436 101.760 1.00 62.54  ?  6   SER A CA  1 
ATOM   11   C C   . SER A 1 6   ? 67.691  113.801 101.742 1.00 62.54  ?  6   SER A C   1 
ATOM   12   O O   . SER A 1 6   ? 68.920  113.914 101.749 1.00 62.54  ?  6   SER A O   1 
ATOM   13   C CB  . SER A 1 6   ? 66.652  112.046 103.194 1.00 62.54  ?  6   SER A CB  1 
ATOM   14   O OG  . SER A 1 6   ? 67.818  111.907 103.987 1.00 62.54  ?  6   SER A OG  1 
ATOM   15   N N   . ALA A 1 7   ? 66.868  114.852 101.722 1.00 63.26  ?  7   ALA A N   1 
ATOM   16   C CA  . ALA A 1 7   ? 67.403  116.209 101.699 1.00 63.26  ?  7   ALA A CA  1 
ATOM   17   C C   . ALA A 1 7   ? 68.021  116.583 103.041 1.00 63.26  ?  7   ALA A C   1 
ATOM   18   O O   . ALA A 1 7   ? 69.052  117.266 103.086 1.00 63.26  ?  7   ALA A O   1 
ATOM   19   C CB  . ALA A 1 7   ? 66.301  117.199 101.322 1.00 63.26  ?  7   ALA A CB  1 
ATOM   20   N N   . GLU A 1 8   ? 67.403  116.155 104.144 1.00 62.56  ?  8   GLU A N   1 
ATOM   21   C CA  . GLU A 1 8   ? 67.972  116.434 105.458 1.00 62.56  ?  8   GLU A CA  1 
ATOM   22   C C   . GLU A 1 8   ? 69.348  115.796 105.602 1.00 62.56  ?  8   GLU A C   1 
ATOM   23   O O   . GLU A 1 8   ? 70.262  116.396 106.179 1.00 62.56  ?  8   GLU A O   1 
ATOM   24   C CB  . GLU A 1 8   ? 67.033  115.935 106.556 1.00 62.56  ?  8   GLU A CB  1 
ATOM   25   C CG  . GLU A 1 8   ? 65.668  116.603 106.555 1.00 62.56  ?  8   GLU A CG  1 
ATOM   26   C CD  . GLU A 1 8   ? 64.819  116.194 107.742 1.00 62.56  ?  8   GLU A CD  1 
ATOM   27   O OE1 . GLU A 1 8   ? 65.310  115.418 108.588 1.00 62.56  ?  8   GLU A OE1 1 
ATOM   28   O OE2 . GLU A 1 8   ? 63.659  116.649 107.830 1.00 62.56  ?  8   GLU A OE2 1 
ATOM   29   N N   . ASP A 1 9   ? 69.516  114.580 105.079 1.00 61.29  ?  9   ASP A N   1 
ATOM   30   C CA  . ASP A 1 9   ? 70.821  113.932 105.136 1.00 61.29  ?  9   ASP A CA  1 
ATOM   31   C C   . ASP A 1 9   ? 71.849  114.699 104.313 1.00 61.29  ?  9   ASP A C   1 
ATOM   32   O O   . ASP A 1 9   ? 73.009  114.823 104.719 1.00 61.29  ?  9   ASP A O   1 
ATOM   33   C CB  . ASP A 1 9   ? 70.714  112.488 104.649 1.00 61.29  ?  9   ASP A CB  1 
ATOM   34   C CG  . ASP A 1 9   ? 72.007  111.716 104.829 1.00 61.29  ?  9   ASP A CG  1 
ATOM   35   O OD1 . ASP A 1 9   ? 72.313  111.326 105.975 1.00 61.29  ?  9   ASP A OD1 1 
ATOM   36   O OD2 . ASP A 1 9   ? 72.719  111.504 103.826 1.00 61.29  ?  9   ASP A OD2 1 
ATOM   37   N N   . LYS A 1 10  ? 71.442  115.226 103.156 1.00 62.14  ?  10  LYS A N   1 
ATOM   38   C CA  . LYS A 1 10  ? 72.361  116.019 102.346 1.00 62.14  ?  10  LYS A CA  1 
ATOM   39   C C   . LYS A 1 10  ? 72.760  117.304 103.063 1.00 62.14  ?  10  LYS A C   1 
ATOM   40   O O   . LYS A 1 10  ? 73.928  117.708 103.025 1.00 62.14  ?  10  LYS A O   1 
ATOM   41   C CB  . LYS A 1 10  ? 71.725  116.334 100.993 1.00 62.14  ?  10  LYS A CB  1 
ATOM   42   C CG  . LYS A 1 10  ? 71.476  115.106 100.129 1.00 62.14  ?  10  LYS A CG  1 
ATOM   43   C CD  . LYS A 1 10  ? 70.627  115.433 98.910  1.00 62.14  ?  10  LYS A CD  1 
ATOM   44   C CE  . LYS A 1 10  ? 71.363  116.336 97.934  1.00 62.14  ?  10  LYS A CE  1 
ATOM   45   N NZ  . LYS A 1 10  ? 70.535  116.647 96.735  1.00 62.14  1  10  LYS A NZ  1 
ATOM   46   N N   . ALA A 1 11  ? 71.804  117.959 103.726 1.00 60.54  ?  11  ALA A N   1 
ATOM   47   C CA  . ALA A 1 11  ? 72.131  119.162 104.483 1.00 60.54  ?  11  ALA A CA  1 
ATOM   48   C C   . ALA A 1 11  ? 73.070  118.841 105.639 1.00 60.54  ?  11  ALA A C   1 
ATOM   49   O O   . ALA A 1 11  ? 74.000  119.606 105.928 1.00 60.54  ?  11  ALA A O   1 
ATOM   50   C CB  . ALA A 1 11  ? 70.853  119.823 104.996 1.00 60.54  ?  11  ALA A CB  1 
ATOM   51   N N   . ALA A 1 12  ? 72.846  117.710 106.311 1.00 58.88  ?  12  ALA A N   1 
ATOM   52   C CA  . ALA A 1 12  ? 73.744  117.303 107.386 1.00 58.88  ?  12  ALA A CA  1 
ATOM   53   C C   . ALA A 1 12  ? 75.140  117.009 106.851 1.00 58.88  ?  12  ALA A C   1 
ATOM   54   O O   . ALA A 1 12  ? 76.140  117.346 107.493 1.00 58.88  ?  12  ALA A O   1 
ATOM   55   C CB  . ALA A 1 12  ? 73.177  116.082 108.109 1.00 58.88  ?  12  ALA A CB  1 
ATOM   56   N N   . VAL A 1 13  ? 75.228  116.389 105.674 1.00 59.24  ?  13  VAL A N   1 
ATOM   57   C CA  . VAL A 1 13  ? 76.529  116.111 105.075 1.00 59.24  ?  13  VAL A CA  1 
ATOM   58   C C   . VAL A 1 13  ? 77.236  117.411 104.713 1.00 59.24  ?  13  VAL A C   1 
ATOM   59   O O   . VAL A 1 13  ? 78.454  117.537 104.878 1.00 59.24  ?  13  VAL A O   1 
ATOM   60   C CB  . VAL A 1 13  ? 76.367  115.195 103.848 1.00 59.24  ?  13  VAL A CB  1 
ATOM   61   C CG1 . VAL A 1 13  ? 77.704  114.998 103.147 1.00 59.24  ?  13  VAL A CG1 1 
ATOM   62   C CG2 . VAL A 1 13  ? 75.773  113.854 104.261 1.00 59.24  ?  13  VAL A CG2 1 
ATOM   63   N N   . GLU A 1 14  ? 76.489  118.398 104.217 1.00 60.77  ?  14  GLU A N   1 
ATOM   64   C CA  . GLU A 1 14  ? 77.091  119.689 103.896 1.00 60.77  ?  14  GLU A CA  1 
ATOM   65   C C   . GLU A 1 14  ? 77.595  120.385 105.156 1.00 60.77  ?  14  GLU A C   1 
ATOM   66   O O   . GLU A 1 14  ? 78.684  120.974 105.165 1.00 60.77  ?  14  GLU A O   1 
ATOM   67   C CB  . GLU A 1 14  ? 76.080  120.569 103.160 1.00 60.77  ?  14  GLU A CB  1 
ATOM   68   C CG  . GLU A 1 14  ? 76.632  121.918 102.727 1.00 60.77  ?  14  GLU A CG  1 
ATOM   69   C CD  . GLU A 1 14  ? 75.619  122.741 101.959 1.00 60.77  ?  14  GLU A CD  1 
ATOM   70   O OE1 . GLU A 1 14  ? 74.483  122.258 101.766 1.00 60.77  ?  14  GLU A OE1 1 
ATOM   71   O OE2 . GLU A 1 14  ? 75.957  123.871 101.548 1.00 60.77  ?  14  GLU A OE2 1 
ATOM   72   N N   . ARG A 1 15  ? 76.807  120.335 106.232 1.00 58.96  ?  15  ARG A N   1 
ATOM   73   C CA  . ARG A 1 15  ? 77.249  120.918 107.495 1.00 58.96  ?  15  ARG A CA  1 
ATOM   74   C C   . ARG A 1 15  ? 78.494  120.209 108.013 1.00 58.96  ?  15  ARG A C   1 
ATOM   75   O O   . ARG A 1 15  ? 79.412  120.848 108.541 1.00 58.96  ?  15  ARG A O   1 
ATOM   76   C CB  . ARG A 1 15  ? 76.121  120.849 108.525 1.00 58.96  ?  15  ARG A CB  1 
ATOM   77   C CG  . ARG A 1 15  ? 76.341  121.723 109.750 1.00 58.96  ?  15  ARG A CG  1 
ATOM   78   C CD  . ARG A 1 15  ? 75.139  121.682 110.682 1.00 58.96  ?  15  ARG A CD  1 
ATOM   79   N NE  . ARG A 1 15  ? 75.232  122.681 111.745 1.00 58.96  ?  15  ARG A NE  1 
ATOM   80   C CZ  . ARG A 1 15  ? 75.865  122.499 112.901 1.00 58.96  ?  15  ARG A CZ  1 
ATOM   81   N NH1 . ARG A 1 15  ? 76.477  121.351 113.161 1.00 58.96  1  15  ARG A NH1 1 
ATOM   82   N NH2 . ARG A 1 15  ? 75.889  123.473 113.801 1.00 58.96  ?  15  ARG A NH2 1 
ATOM   83   N N   . SER A 1 16  ? 78.547  118.884 107.861 1.00 58.12  ?  16  SER A N   1 
ATOM   84   C CA  . SER A 1 16  ? 79.730  118.137 108.274 1.00 58.12  ?  16  SER A CA  1 
ATOM   85   C C   . SER A 1 16  ? 80.939  118.519 107.432 1.00 58.12  ?  16  SER A C   1 
ATOM   86   O O   . SER A 1 16  ? 82.059  118.605 107.944 1.00 58.12  ?  16  SER A O   1 
ATOM   87   C CB  . SER A 1 16  ? 79.460  116.636 108.177 1.00 58.12  ?  16  SER A CB  1 
ATOM   88   O OG  . SER A 1 16  ? 80.590  115.887 108.591 1.00 58.12  ?  16  SER A OG  1 
ATOM   89   N N   . LYS A 1 17  ? 80.733  118.759 106.135 1.00 59.36  ?  17  LYS A N   1 
ATOM   90   C CA  . LYS A 1 17  ? 81.836  119.193 105.284 1.00 59.36  ?  17  LYS A CA  1 
ATOM   91   C C   . LYS A 1 17  ? 82.340  120.572 105.687 1.00 59.36  ?  17  LYS A C   1 
ATOM   92   O O   . LYS A 1 17  ? 83.551  120.816 105.676 1.00 59.36  ?  17  LYS A O   1 
ATOM   93   C CB  . LYS A 1 17  ? 81.402  119.194 103.818 1.00 59.36  ?  17  LYS A CB  1 
ATOM   94   C CG  . LYS A 1 17  ? 81.257  117.808 103.214 1.00 59.36  ?  17  LYS A CG  1 
ATOM   95   C CD  . LYS A 1 17  ? 80.777  117.879 101.773 1.00 59.36  ?  17  LYS A CD  1 
ATOM   96   C CE  . LYS A 1 17  ? 80.633  116.494 101.163 1.00 59.36  ?  17  LYS A CE  1 
ATOM   97   N NZ  . LYS A 1 17  ? 81.932  115.767 101.093 1.00 59.36  1  17  LYS A NZ  1 
ATOM   98   N N   . MET A 1 18  ? 81.435  121.482 106.047 1.00 61.16  ?  18  MET A N   1 
ATOM   99   C CA  . MET A 1 18  ? 81.864  122.785 106.549 1.00 61.16  ?  18  MET A CA  1 
ATOM   100  C C   . MET A 1 18  ? 82.626  122.659 107.864 1.00 61.16  ?  18  MET A C   1 
ATOM   101  O O   . MET A 1 18  ? 83.643  123.341 108.064 1.00 61.16  ?  18  MET A O   1 
ATOM   102  C CB  . MET A 1 18  ? 80.655  123.703 106.732 1.00 61.16  ?  18  MET A CB  1 
ATOM   103  C CG  . MET A 1 18  ? 79.935  124.047 105.438 1.00 61.16  ?  18  MET A CG  1 
ATOM   104  S SD  . MET A 1 18  ? 78.461  125.054 105.696 1.00 61.16  ?  18  MET A SD  1 
ATOM   105  C CE  . MET A 1 18  ? 79.173  126.540 106.398 1.00 61.16  ?  18  MET A CE  1 
ATOM   106  N N   . ILE A 1 19  ? 82.152  121.798 108.767 1.00 58.63  ?  19  ILE A N   1 
ATOM   107  C CA  . ILE A 1 19  ? 82.866  121.576 110.019 1.00 58.63  ?  19  ILE A CA  1 
ATOM   108  C C   . ILE A 1 19  ? 84.244  120.987 109.745 1.00 58.63  ?  19  ILE A C   1 
ATOM   109  O O   . ILE A 1 19  ? 85.217  121.312 110.431 1.00 58.63  ?  19  ILE A O   1 
ATOM   110  C CB  . ILE A 1 19  ? 82.038  120.676 110.955 1.00 58.63  ?  19  ILE A CB  1 
ATOM   111  C CG1 . ILE A 1 19  ? 80.740  121.383 111.357 1.00 58.63  ?  19  ILE A CG1 1 
ATOM   112  C CG2 . ILE A 1 19  ? 82.847  120.314 112.195 1.00 58.63  ?  19  ILE A CG2 1 
ATOM   113  C CD1 . ILE A 1 19  ? 79.743  120.488 112.065 1.00 58.63  ?  19  ILE A CD1 1 
ATOM   114  N N   . GLU A 1 20  ? 84.352  120.117 108.738 1.00 58.68  ?  20  GLU A N   1 
ATOM   115  C CA  . GLU A 1 20  ? 85.651  119.559 108.377 1.00 58.68  ?  20  GLU A CA  1 
ATOM   116  C C   . GLU A 1 20  ? 86.569  120.631 107.806 1.00 58.68  ?  20  GLU A C   1 
ATOM   117  O O   . GLU A 1 20  ? 87.774  120.639 108.080 1.00 58.68  ?  20  GLU A O   1 
ATOM   118  C CB  . GLU A 1 20  ? 85.474  118.420 107.373 1.00 58.68  ?  20  GLU A CB  1 
ATOM   119  C CG  . GLU A 1 20  ? 84.900  117.148 107.970 1.00 58.68  ?  20  GLU A CG  1 
ATOM   120  C CD  . GLU A 1 20  ? 84.666  116.072 106.929 1.00 58.68  ?  20  GLU A CD  1 
ATOM   121  O OE1 . GLU A 1 20  ? 84.953  116.322 105.739 1.00 58.68  ?  20  GLU A OE1 1 
ATOM   122  O OE2 . GLU A 1 20  ? 84.196  114.976 107.300 1.00 58.68  ?  20  GLU A OE2 1 
ATOM   123  N N   . LYS A 1 21  ? 86.019  121.537 106.996 1.00 60.01  ?  21  LYS A N   1 
ATOM   124  C CA  . LYS A 1 21  ? 86.800  122.668 106.507 1.00 60.01  ?  21  LYS A CA  1 
ATOM   125  C C   . LYS A 1 21  ? 87.369  123.471 107.670 1.00 60.01  ?  21  LYS A C   1 
ATOM   126  O O   . LYS A 1 21  ? 88.562  123.800 107.697 1.00 60.01  ?  21  LYS A O   1 
ATOM   127  C CB  . LYS A 1 21  ? 85.930  123.557 105.617 1.00 60.01  ?  21  LYS A CB  1 
ATOM   128  C CG  . LYS A 1 21  ? 85.530  122.924 104.294 1.00 60.01  ?  21  LYS A CG  1 
ATOM   129  C CD  . LYS A 1 21  ? 86.673  122.951 103.293 1.00 60.01  ?  21  LYS A CD  1 
ATOM   130  C CE  . LYS A 1 21  ? 86.262  122.342 101.961 1.00 60.01  ?  21  LYS A CE  1 
ATOM   131  N NZ  . LYS A 1 21  ? 85.104  123.052 101.349 1.00 60.01  1  21  LYS A NZ  1 
ATOM   132  N N   . GLN A 1 22  ? 86.519  123.795 108.648 1.00 59.59  ?  22  GLN A N   1 
ATOM   133  C CA  . GLN A 1 22  ? 86.984  124.564 109.800 1.00 59.59  ?  22  GLN A CA  1 
ATOM   134  C C   . GLN A 1 22  ? 88.017  123.783 110.607 1.00 59.59  ?  22  GLN A C   1 
ATOM   135  O O   . GLN A 1 22  ? 89.014  124.351 111.073 1.00 59.59  ?  22  GLN A O   1 
ATOM   136  C CB  . GLN A 1 22  ? 85.797  124.955 110.681 1.00 59.59  ?  22  GLN A CB  1 
ATOM   137  C CG  . GLN A 1 22  ? 86.173  125.776 111.909 1.00 59.59  ?  22  GLN A CG  1 
ATOM   138  C CD  . GLN A 1 22  ? 86.901  127.060 111.557 1.00 59.59  ?  22  GLN A CD  1 
ATOM   139  O OE1 . GLN A 1 22  ? 86.834  127.535 110.423 1.00 59.59  ?  22  GLN A OE1 1 
ATOM   140  N NE2 . GLN A 1 22  ? 87.604  127.628 112.530 1.00 59.59  ?  22  GLN A NE2 1 
ATOM   141  N N   . LEU A 1 23  ? 87.798  122.477 110.777 1.00 58.71  ?  23  LEU A N   1 
ATOM   142  C CA  . LEU A 1 23  ? 88.737  121.658 111.533 1.00 58.71  ?  23  LEU A CA  1 
ATOM   143  C C   . LEU A 1 23  ? 90.089  121.581 110.842 1.00 58.71  ?  23  LEU A C   1 
ATOM   144  O O   . LEU A 1 23  ? 91.123  121.581 111.511 1.00 58.71  ?  23  LEU A O   1 
ATOM   145  C CB  . LEU A 1 23  ? 88.160  120.257 111.737 1.00 58.71  ?  23  LEU A CB  1 
ATOM   146  C CG  . LEU A 1 23  ? 86.990  120.154 112.718 1.00 58.71  ?  23  LEU A CG  1 
ATOM   147  C CD1 . LEU A 1 23  ? 86.336  118.787 112.622 1.00 58.71  ?  23  LEU A CD1 1 
ATOM   148  C CD2 . LEU A 1 23  ? 87.453  120.427 114.141 1.00 58.71  ?  23  LEU A CD2 1 
ATOM   149  N N   . GLN A 1 24  ? 90.106  121.524 109.510 1.00 60.13  ?  24  GLN A N   1 
ATOM   150  C CA  . GLN A 1 24  ? 91.373  121.537 108.786 1.00 60.13  ?  24  GLN A CA  1 
ATOM   151  C C   . GLN A 1 24  ? 92.053  122.897 108.886 1.00 60.13  ?  24  GLN A C   1 
ATOM   152  O O   . GLN A 1 24  ? 93.278  122.974 109.050 1.00 60.13  ?  24  GLN A O   1 
ATOM   153  C CB  . GLN A 1 24  ? 91.144  121.162 107.321 1.00 60.13  ?  24  GLN A CB  1 
ATOM   154  C CG  . GLN A 1 24  ? 90.700  119.721 107.105 1.00 60.13  ?  24  GLN A CG  1 
ATOM   155  C CD  . GLN A 1 24  ? 91.719  118.703 107.587 1.00 60.13  ?  24  GLN A CD  1 
ATOM   156  O OE1 . GLN A 1 24  ? 91.358  117.665 108.142 1.00 60.13  ?  24  GLN A OE1 1 
ATOM   157  N NE2 . GLN A 1 24  ? 92.999  118.990 107.371 1.00 60.13  ?  24  GLN A NE2 1 
ATOM   158  N N   . LYS A 1 25  ? 91.277  123.980 108.784 1.00 60.12  ?  25  LYS A N   1 
ATOM   159  C CA  . LYS A 1 25  ? 91.849  125.310 108.966 1.00 60.12  ?  25  LYS A CA  1 
ATOM   160  C C   . LYS A 1 25  ? 92.496  125.450 110.337 1.00 60.12  ?  25  LYS A C   1 
ATOM   161  O O   . LYS A 1 25  ? 93.539  126.101 110.469 1.00 60.12  ?  25  LYS A O   1 
ATOM   162  C CB  . LYS A 1 25  ? 90.773  126.379 108.780 1.00 60.12  ?  25  LYS A CB  1 
ATOM   163  C CG  . LYS A 1 25  ? 90.295  126.538 107.346 1.00 60.12  ?  25  LYS A CG  1 
ATOM   164  C CD  . LYS A 1 25  ? 89.216  127.605 107.239 1.00 60.12  ?  25  LYS A CD  1 
ATOM   165  C CE  . LYS A 1 25  ? 88.717  127.756 105.810 1.00 60.12  ?  25  LYS A CE  1 
ATOM   166  N NZ  . LYS A 1 25  ? 88.106  126.500 105.294 1.00 60.12  1  25  LYS A NZ  1 
ATOM   167  N N   . ASP A 1 26  ? 91.895  124.850 111.366 1.00 60.31  ?  26  ASP A N   1 
ATOM   168  C CA  . ASP A 1 26  ? 92.480  124.904 112.702 1.00 60.31  ?  26  ASP A CA  1 
ATOM   169  C C   . ASP A 1 26  ? 93.664  123.952 112.844 1.00 60.31  ?  26  ASP A C   1 
ATOM   170  O O   . ASP A 1 26  ? 94.647  124.285 113.517 1.00 60.31  ?  26  ASP A O   1 
ATOM   171  C CB  . ASP A 1 26  ? 91.414  124.578 113.750 1.00 60.31  ?  26  ASP A CB  1 
ATOM   172  C CG  . ASP A 1 26  ? 91.849  124.931 115.162 1.00 60.31  ?  26  ASP A CG  1 
ATOM   173  O OD1 . ASP A 1 26  ? 93.065  124.908 115.444 1.00 60.31  ?  26  ASP A OD1 1 
ATOM   174  O OD2 . ASP A 1 26  ? 90.967  125.232 115.994 1.00 60.31  ?  26  ASP A OD2 1 
ATOM   175  N N   . LYS A 1 27  ? 93.593  122.777 112.214 1.00 59.41  ?  27  LYS A N   1 
ATOM   176  C CA  . LYS A 1 27  ? 94.678  121.809 112.302 1.00 59.41  ?  27  LYS A CA  1 
ATOM   177  C C   . LYS A 1 27  ? 95.935  122.320 111.616 1.00 59.41  ?  27  LYS A C   1 
ATOM   178  O O   . LYS A 1 27  ? 97.046  121.967 112.023 1.00 59.41  ?  27  LYS A O   1 
ATOM   179  C CB  . LYS A 1 27  ? 94.243  120.481 111.684 1.00 59.41  ?  27  LYS A CB  1 
ATOM   180  C CG  . LYS A 1 27  ? 95.150  119.308 112.017 1.00 59.41  ?  27  LYS A CG  1 
ATOM   181  C CD  . LYS A 1 27  ? 94.690  118.041 111.313 1.00 59.41  ?  27  LYS A CD  1 
ATOM   182  C CE  . LYS A 1 27  ? 95.393  116.811 111.861 1.00 59.41  ?  27  LYS A CE  1 
ATOM   183  N NZ  . LYS A 1 27  ? 94.914  115.560 111.209 1.00 59.41  1  27  LYS A NZ  1 
ATOM   184  N N   . GLN A 1 28  ? 95.783  123.133 110.570 1.00 61.35  ?  28  GLN A N   1 
ATOM   185  C CA  . GLN A 1 28  ? 96.943  123.780 109.967 1.00 61.35  ?  28  GLN A CA  1 
ATOM   186  C C   . GLN A 1 28  ? 97.756  124.514 111.028 1.00 61.35  ?  28  GLN A C   1 
ATOM   187  O O   . GLN A 1 28  ? 98.950  124.251 111.216 1.00 61.35  ?  28  GLN A O   1 
ATOM   188  C CB  . GLN A 1 28  ? 96.493  124.742 108.866 1.00 61.35  ?  28  GLN A CB  1 
ATOM   189  C CG  . GLN A 1 28  ? 96.002  124.057 107.601 1.00 61.35  ?  28  GLN A CG  1 
ATOM   190  C CD  . GLN A 1 28  ? 95.457  125.039 106.581 1.00 61.35  ?  28  GLN A CD  1 
ATOM   191  O OE1 . GLN A 1 28  ? 95.592  126.253 106.738 1.00 61.35  ?  28  GLN A OE1 1 
ATOM   192  N NE2 . GLN A 1 28  ? 94.834  124.517 105.531 1.00 61.35  ?  28  GLN A NE2 1 
ATOM   193  N N   . VAL A 1 29  ? 97.109  125.434 111.747 1.00 59.85  ?  29  VAL A N   1 
ATOM   194  C CA  . VAL A 1 29  ? 97.795  126.186 112.795 1.00 59.85  ?  29  VAL A CA  1 
ATOM   195  C C   . VAL A 1 29  ? 98.302  125.242 113.878 1.00 59.85  ?  29  VAL A C   1 
ATOM   196  O O   . VAL A 1 29  ? 99.440  125.362 114.346 1.00 59.85  ?  29  VAL A O   1 
ATOM   197  C CB  . VAL A 1 29  ? 96.863  127.263 113.379 1.00 59.85  ?  29  VAL A CB  1 
ATOM   198  C CG1 . VAL A 1 29  ? 97.535  127.964 114.555 1.00 59.85  ?  29  VAL A CG1 1 
ATOM   199  C CG2 . VAL A 1 29  ? 96.461  128.263 112.297 1.00 59.85  ?  29  VAL A CG2 1 
ATOM   200  N N   . TYR A 1 30  ? 97.461  124.294 114.298 1.00 59.56  ?  30  TYR A N   1 
ATOM   201  C CA  . TYR A 1 30  ? 97.855  123.347 115.338 1.00 59.56  ?  30  TYR A CA  1 
ATOM   202  C C   . TYR A 1 30  ? 99.190  122.690 115.004 1.00 59.56  ?  30  TYR A C   1 
ATOM   203  O O   . TYR A 1 30  ? 100.166 122.811 115.752 1.00 59.56  ?  30  TYR A O   1 
ATOM   204  C CB  . TYR A 1 30  ? 96.762  122.291 115.515 1.00 59.56  ?  30  TYR A CB  1 
ATOM   205  C CG  . TYR A 1 30  ? 97.098  121.219 116.529 1.00 59.56  ?  30  TYR A CG  1 
ATOM   206  C CD1 . TYR A 1 30  ? 96.860  121.417 117.883 1.00 59.56  ?  30  TYR A CD1 1 
ATOM   207  C CD2 . TYR A 1 30  ? 97.648  120.007 116.132 1.00 59.56  ?  30  TYR A CD2 1 
ATOM   208  C CE1 . TYR A 1 30  ? 97.163  120.440 118.813 1.00 59.56  ?  30  TYR A CE1 1 
ATOM   209  C CE2 . TYR A 1 30  ? 97.955  119.024 117.054 1.00 59.56  ?  30  TYR A CE2 1 
ATOM   210  C CZ  . TYR A 1 30  ? 97.710  119.246 118.392 1.00 59.56  ?  30  TYR A CZ  1 
ATOM   211  O OH  . TYR A 1 30  ? 98.014  118.270 119.314 1.00 59.56  ?  30  TYR A OH  1 
ATOM   212  N N   . ARG A 1 31  ? 99.244  121.987 113.872 1.00 60.35  ?  31  ARG A N   1 
ATOM   213  C CA  . ARG A 1 31  ? 100.481 121.356 113.428 1.00 60.35  ?  31  ARG A CA  1 
ATOM   214  C C   . ARG A 1 31  ? 101.613 122.369 113.321 1.00 60.35  ?  31  ARG A C   1 
ATOM   215  O O   . ARG A 1 31  ? 102.748 122.098 113.728 1.00 60.35  ?  31  ARG A O   1 
ATOM   216  C CB  . ARG A 1 31  ? 100.248 120.663 112.082 1.00 60.35  ?  31  ARG A CB  1 
ATOM   217  C CG  . ARG A 1 31  ? 101.488 120.010 111.490 1.00 60.35  ?  31  ARG A CG  1 
ATOM   218  C CD  . ARG A 1 31  ? 101.167 119.240 110.216 1.00 60.35  ?  31  ARG A CD  1 
ATOM   219  N NE  . ARG A 1 31  ? 100.573 120.090 109.185 1.00 60.35  ?  31  ARG A NE  1 
ATOM   220  C CZ  . ARG A 1 31  ? 99.266  120.274 109.013 1.00 60.35  ?  31  ARG A CZ  1 
ATOM   221  N NH1 . ARG A 1 31  ? 98.386  119.671 109.803 1.00 60.35  1  31  ARG A NH1 1 
ATOM   222  N NH2 . ARG A 1 31  ? 98.834  121.068 108.043 1.00 60.35  ?  31  ARG A NH2 1 
ATOM   223  N N   . ARG A 1 32  ? 101.320 123.550 112.774 1.00 60.47  ?  32  ARG A N   1 
ATOM   224  C CA  . ARG A 1 32  ? 102.342 124.572 112.588 1.00 60.47  ?  32  ARG A CA  1 
ATOM   225  C C   . ARG A 1 32  ? 102.742 125.262 113.887 1.00 60.47  ?  32  ARG A C   1 
ATOM   226  O O   . ARG A 1 32  ? 103.648 126.102 113.865 1.00 60.47  ?  32  ARG A O   1 
ATOM   227  C CB  . ARG A 1 32  ? 101.851 125.612 111.578 1.00 60.47  ?  32  ARG A CB  1 
ATOM   228  C CG  . ARG A 1 32  ? 101.675 125.054 110.173 1.00 60.47  ?  32  ARG A CG  1 
ATOM   229  C CD  . ARG A 1 32  ? 100.919 126.013 109.270 1.00 60.47  ?  32  ARG A CD  1 
ATOM   230  N NE  . ARG A 1 32  ? 100.694 125.442 107.944 1.00 60.47  ?  32  ARG A NE  1 
ATOM   231  C CZ  . ARG A 1 32  ? 99.976  126.023 106.987 1.00 60.47  ?  32  ARG A CZ  1 
ATOM   232  N NH1 . ARG A 1 32  ? 99.830  125.424 105.813 1.00 60.47  1  32  ARG A NH1 1 
ATOM   233  N NH2 . ARG A 1 32  ? 99.399  127.198 107.202 1.00 60.47  ?  32  ARG A NH2 1 
ATOM   234  N N   . THR A 1 33  ? 102.099 124.934 115.005 1.00 61.47  ?  33  THR A N   1 
ATOM   235  C CA  . THR A 1 33  ? 102.472 125.498 116.292 1.00 61.47  ?  33  THR A CA  1 
ATOM   236  C C   . THR A 1 33  ? 103.483 124.597 117.001 1.00 61.47  ?  33  THR A C   1 
ATOM   237  O O   . THR A 1 33  ? 103.795 123.489 116.556 1.00 61.47  ?  33  THR A O   1 
ATOM   238  C CB  . THR A 1 33  ? 101.237 125.700 117.170 1.00 61.47  ?  33  THR A CB  1 
ATOM   239  O OG1 . THR A 1 33  ? 100.405 124.535 117.111 1.00 61.47  ?  33  THR A OG1 1 
ATOM   240  C CG2 . THR A 1 33  ? 100.448 126.919 116.714 1.00 61.47  ?  33  THR A CG2 1 
ATOM   241  N N   . LEU A 1 34  ? 103.998 125.093 118.125 1.00 60.04  ?  34  LEU A N   1 
ATOM   242  C CA  . LEU A 1 34  ? 104.996 124.385 118.928 1.00 60.04  ?  34  LEU A CA  1 
ATOM   243  C C   . LEU A 1 34  ? 104.607 124.525 120.398 1.00 60.04  ?  34  LEU A C   1 
ATOM   244  O O   . LEU A 1 34  ? 104.685 125.619 120.965 1.00 60.04  ?  34  LEU A O   1 
ATOM   245  C CB  . LEU A 1 34  ? 106.396 124.933 118.669 1.00 60.04  ?  34  LEU A CB  1 
ATOM   246  C CG  . LEU A 1 34  ? 106.907 124.796 117.233 1.00 60.04  ?  34  LEU A CG  1 
ATOM   247  C CD1 . LEU A 1 34  ? 108.224 125.537 117.063 1.00 60.04  ?  34  LEU A CD1 1 
ATOM   248  C CD2 . LEU A 1 34  ? 107.063 123.332 116.847 1.00 60.04  ?  34  LEU A CD2 1 
ATOM   249  N N   . ARG A 1 35  ? 104.190 123.419 121.009 1.00 60.73  ?  35  ARG A N   1 
ATOM   250  C CA  . ARG A 1 35  ? 103.768 123.430 122.403 1.00 60.73  ?  35  ARG A CA  1 
ATOM   251  C C   . ARG A 1 35  ? 104.967 123.219 123.320 1.00 60.73  ?  35  ARG A C   1 
ATOM   252  O O   . ARG A 1 35  ? 105.784 122.321 123.093 1.00 60.73  ?  35  ARG A O   1 
ATOM   253  C CB  . ARG A 1 35  ? 102.718 122.346 122.653 1.00 60.73  ?  35  ARG A CB  1 
ATOM   254  C CG  . ARG A 1 35  ? 101.333 122.657 122.090 1.00 60.73  ?  35  ARG A CG  1 
ATOM   255  C CD  . ARG A 1 35  ? 101.278 122.548 120.570 1.00 60.73  ?  35  ARG A CD  1 
ATOM   256  N NE  . ARG A 1 35  ? 101.657 121.220 120.096 1.00 60.73  ?  35  ARG A NE  1 
ATOM   257  C CZ  . ARG A 1 35  ? 101.672 120.855 118.817 1.00 60.73  ?  35  ARG A CZ  1 
ATOM   258  N NH1 . ARG A 1 35  ? 102.031 119.623 118.484 1.00 60.73  1  35  ARG A NH1 1 
ATOM   259  N NH2 . ARG A 1 35  ? 101.328 121.719 117.870 1.00 60.73  ?  35  ARG A NH2 1 
ATOM   260  N N   . LEU A 1 36  ? 105.065 124.046 124.359 1.00 60.21  ?  36  LEU A N   1 
ATOM   261  C CA  . LEU A 1 36  ? 106.133 123.961 125.345 1.00 60.21  ?  36  LEU A CA  1 
ATOM   262  C C   . LEU A 1 36  ? 105.522 123.855 126.733 1.00 60.21  ?  36  LEU A C   1 
ATOM   263  O O   . LEU A 1 36  ? 104.501 124.489 127.019 1.00 60.21  ?  36  LEU A O   1 
ATOM   264  C CB  . LEU A 1 36  ? 107.058 125.183 125.275 1.00 60.21  ?  36  LEU A CB  1 
ATOM   265  C CG  . LEU A 1 36  ? 107.746 125.436 123.932 1.00 60.21  ?  36  LEU A CG  1 
ATOM   266  C CD1 . LEU A 1 36  ? 108.374 126.819 123.913 1.00 60.21  ?  36  LEU A CD1 1 
ATOM   267  C CD2 . LEU A 1 36  ? 108.795 124.373 123.654 1.00 60.21  ?  36  LEU A CD2 1 
ATOM   268  N N   . LEU A 1 37  ? 106.149 123.057 127.595 1.00 59.33  ?  37  LEU A N   1 
ATOM   269  C CA  . LEU A 1 37  ? 105.658 122.820 128.951 1.00 59.33  ?  37  LEU A CA  1 
ATOM   270  C C   . LEU A 1 37  ? 106.642 123.422 129.947 1.00 59.33  ?  37  LEU A C   1 
ATOM   271  O O   . LEU A 1 37  ? 107.767 122.936 130.084 1.00 59.33  ?  37  LEU A O   1 
ATOM   272  C CB  . LEU A 1 37  ? 105.470 121.326 129.208 1.00 59.33  ?  37  LEU A CB  1 
ATOM   273  C CG  . LEU A 1 37  ? 105.139 120.944 130.653 1.00 59.33  ?  37  LEU A CG  1 
ATOM   274  C CD1 . LEU A 1 37  ? 103.874 121.644 131.125 1.00 59.33  ?  37  LEU A CD1 1 
ATOM   275  C CD2 . LEU A 1 37  ? 105.004 119.440 130.791 1.00 59.33  ?  37  LEU A CD2 1 
ATOM   276  N N   . LEU A 1 38  ? 106.212 124.466 130.651 1.00 61.30  ?  38  LEU A N   1 
ATOM   277  C CA  . LEU A 1 38  ? 107.037 125.107 131.668 1.00 61.30  ?  38  LEU A CA  1 
ATOM   278  C C   . LEU A 1 38  ? 106.734 124.481 133.025 1.00 61.30  ?  38  LEU A C   1 
ATOM   279  O O   . LEU A 1 38  ? 105.578 124.465 133.462 1.00 61.30  ?  38  LEU A O   1 
ATOM   280  C CB  . LEU A 1 38  ? 106.781 126.613 131.701 1.00 61.30  ?  38  LEU A CB  1 
ATOM   281  C CG  . LEU A 1 38  ? 107.594 127.413 132.722 1.00 61.30  ?  38  LEU A CG  1 
ATOM   282  C CD1 . LEU A 1 38  ? 109.079 127.358 132.395 1.00 61.30  ?  38  LEU A CD1 1 
ATOM   283  C CD2 . LEU A 1 38  ? 107.111 128.854 132.786 1.00 61.30  ?  38  LEU A CD2 1 
ATOM   284  N N   . LEU A 1 39  ? 107.771 123.970 133.689 1.00 60.57  ?  39  LEU A N   1 
ATOM   285  C CA  . LEU A 1 39  ? 107.638 123.359 135.002 1.00 60.57  ?  39  LEU A CA  1 
ATOM   286  C C   . LEU A 1 39  ? 108.633 123.996 135.961 1.00 60.57  ?  39  LEU A C   1 
ATOM   287  O O   . LEU A 1 39  ? 109.710 124.444 135.557 1.00 60.57  ?  39  LEU A O   1 
ATOM   288  C CB  . LEU A 1 39  ? 107.872 121.842 134.945 1.00 60.57  ?  39  LEU A CB  1 
ATOM   289  C CG  . LEU A 1 39  ? 106.937 121.054 134.025 1.00 60.57  ?  39  LEU A CG  1 
ATOM   290  C CD1 . LEU A 1 39  ? 107.322 119.584 134.002 1.00 60.57  ?  39  LEU A CD1 1 
ATOM   291  C CD2 . LEU A 1 39  ? 105.486 121.221 134.452 1.00 60.57  ?  39  LEU A CD2 1 
ATOM   292  N N   . GLY A 1 40  ? 108.259 124.034 137.237 1.00 63.47  ?  40  GLY A N   1 
ATOM   293  C CA  . GLY A 1 40  ? 109.107 124.618 138.257 1.00 63.47  ?  40  GLY A CA  1 
ATOM   294  C C   . GLY A 1 40  ? 108.401 124.782 139.586 1.00 63.47  ?  40  GLY A C   1 
ATOM   295  O O   . GLY A 1 40  ? 107.200 125.062 139.629 1.00 63.47  ?  40  GLY A O   1 
ATOM   296  N N   . ALA A 1 41  ? 109.139 124.609 140.680 1.00 66.08  ?  41  ALA A N   1 
ATOM   297  C CA  . ALA A 1 41  ? 108.565 124.740 142.009 1.00 66.08  ?  41  ALA A CA  1 
ATOM   298  C C   . ALA A 1 41  ? 108.292 126.211 142.322 1.00 66.08  ?  41  ALA A C   1 
ATOM   299  O O   . ALA A 1 41  ? 108.596 127.114 141.537 1.00 66.08  ?  41  ALA A O   1 
ATOM   300  C CB  . ALA A 1 41  ? 109.495 124.123 143.050 1.00 66.08  ?  41  ALA A CB  1 
ATOM   301  N N   . ASP A 1 42  ? 107.703 126.452 143.496 1.00 68.03  ?  42  ASP A N   1 
ATOM   302  C CA  . ASP A 1 42  ? 107.397 127.820 143.900 1.00 68.03  ?  42  ASP A CA  1 
ATOM   303  C C   . ASP A 1 42  ? 108.666 128.655 144.022 1.00 68.03  ?  42  ASP A C   1 
ATOM   304  O O   . ASP A 1 42  ? 108.695 129.820 143.606 1.00 68.03  ?  42  ASP A O   1 
ATOM   305  C CB  . ASP A 1 42  ? 106.627 127.817 145.221 1.00 68.03  ?  42  ASP A CB  1 
ATOM   306  C CG  . ASP A 1 42  ? 107.377 127.107 146.332 1.00 68.03  ?  42  ASP A CG  1 
ATOM   307  O OD1 . ASP A 1 42  ? 108.473 126.572 146.066 1.00 68.03  ?  42  ASP A OD1 1 
ATOM   308  O OD2 . ASP A 1 42  ? 106.868 127.085 147.473 1.00 68.03  ?  42  ASP A OD2 1 
ATOM   309  N N   . ASN A 1 43  ? 109.727 128.078 144.591 1.00 67.14  ?  43  ASN A N   1 
ATOM   310  C CA  . ASN A 1 43  ? 110.982 128.811 144.719 1.00 67.14  ?  43  ASN A CA  1 
ATOM   311  C C   . ASN A 1 43  ? 111.587 129.121 143.356 1.00 67.14  ?  43  ASN A C   1 
ATOM   312  O O   . ASN A 1 43  ? 112.279 130.134 143.201 1.00 67.14  ?  43  ASN A O   1 
ATOM   313  C CB  . ASN A 1 43  ? 111.972 128.012 145.567 1.00 67.14  ?  43  ASN A CB  1 
ATOM   314  C CG  . ASN A 1 43  ? 113.291 128.734 145.757 1.00 67.14  ?  43  ASN A CG  1 
ATOM   315  O OD1 . ASN A 1 43  ? 113.363 129.959 145.655 1.00 67.14  ?  43  ASN A OD1 1 
ATOM   316  N ND2 . ASN A 1 43  ? 114.346 127.976 146.034 1.00 67.14  ?  43  ASN A ND2 1 
ATOM   317  N N   . SER A 1 44  ? 111.341 128.268 142.365 1.00 65.28  ?  44  SER A N   1 
ATOM   318  C CA  . SER A 1 44  ? 111.872 128.502 141.030 1.00 65.28  ?  44  SER A CA  1 
ATOM   319  C C   . SER A 1 44  ? 111.341 129.816 140.469 1.00 65.28  ?  44  SER A C   1 
ATOM   320  O O   . SER A 1 44  ? 110.233 130.254 140.787 1.00 65.28  ?  44  SER A O   1 
ATOM   321  C CB  . SER A 1 44  ? 111.500 127.345 140.102 1.00 65.28  ?  44  SER A CB  1 
ATOM   322  O OG  . SER A 1 44  ? 110.094 127.206 139.996 1.00 65.28  ?  44  SER A OG  1 
ATOM   323  N N   . GLY A 1 45  ? 112.150 130.447 139.621 1.00 64.95  ?  45  GLY A N   1 
ATOM   324  C CA  . GLY A 1 45  ? 111.789 131.724 139.039 1.00 64.95  ?  45  GLY A CA  1 
ATOM   325  C C   . GLY A 1 45  ? 111.009 131.595 137.748 1.00 64.95  ?  45  GLY A C   1 
ATOM   326  O O   . GLY A 1 45  ? 111.232 132.360 136.804 1.00 64.95  ?  45  GLY A O   1 
ATOM   327  N N   . LYS A 1 46  ? 110.089 130.629 137.690 1.00 64.10  ?  46  LYS A N   1 
ATOM   328  C CA  . LYS A 1 46  ? 109.284 130.455 136.486 1.00 64.10  ?  46  LYS A CA  1 
ATOM   329  C C   . LYS A 1 46  ? 108.391 131.662 136.233 1.00 64.10  ?  46  LYS A C   1 
ATOM   330  O O   . LYS A 1 46  ? 108.155 132.027 135.076 1.00 64.10  ?  46  LYS A O   1 
ATOM   331  C CB  . LYS A 1 46  ? 108.442 129.183 136.597 1.00 64.10  ?  46  LYS A CB  1 
ATOM   332  C CG  . LYS A 1 46  ? 107.481 129.167 137.776 1.00 64.10  ?  46  LYS A CG  1 
ATOM   333  C CD  . LYS A 1 46  ? 106.709 127.859 137.840 1.00 64.10  ?  46  LYS A CD  1 
ATOM   334  C CE  . LYS A 1 46  ? 105.752 127.832 139.020 1.00 64.10  ?  46  LYS A CE  1 
ATOM   335  N NZ  . LYS A 1 46  ? 104.995 126.552 139.096 1.00 64.10  1  46  LYS A NZ  1 
ATOM   336  N N   . SER A 1 47  ? 107.887 132.293 137.295 1.00 66.48  ?  47  SER A N   1 
ATOM   337  C CA  . SER A 1 47  ? 107.078 133.495 137.124 1.00 66.48  ?  47  SER A CA  1 
ATOM   338  C C   . SER A 1 47  ? 107.897 134.613 136.492 1.00 66.48  ?  47  SER A C   1 
ATOM   339  O O   . SER A 1 47  ? 107.438 135.288 135.561 1.00 66.48  ?  47  SER A O   1 
ATOM   340  C CB  . SER A 1 47  ? 106.509 133.938 138.473 1.00 66.48  ?  47  SER A CB  1 
ATOM   341  O OG  . SER A 1 47  ? 105.694 132.927 139.039 1.00 66.48  ?  47  SER A OG  1 
ATOM   342  N N   . THR A 1 48  ? 109.117 134.826 136.989 1.00 68.46  ?  48  THR A N   1 
ATOM   343  C CA  . THR A 1 48  ? 109.989 135.834 136.394 1.00 68.46  ?  48  THR A CA  1 
ATOM   344  C C   . THR A 1 48  ? 110.327 135.490 134.950 1.00 68.46  ?  48  THR A C   1 
ATOM   345  O O   . THR A 1 48  ? 110.453 136.389 134.111 1.00 68.46  ?  48  THR A O   1 
ATOM   346  C CB  . THR A 1 48  ? 111.270 135.974 137.218 1.00 68.46  ?  48  THR A CB  1 
ATOM   347  O OG1 . THR A 1 48  ? 110.938 136.316 138.570 1.00 68.46  ?  48  THR A OG1 1 
ATOM   348  C CG2 . THR A 1 48  ? 112.171 137.053 136.630 1.00 68.46  ?  48  THR A CG2 1 
ATOM   349  N N   . ILE A 1 49  ? 110.471 134.201 134.638 1.00 66.92  ?  49  ILE A N   1 
ATOM   350  C CA  . ILE A 1 49  ? 110.745 133.797 133.263 1.00 66.92  ?  49  ILE A CA  1 
ATOM   351  C C   . ILE A 1 49  ? 109.569 134.152 132.362 1.00 66.92  ?  49  ILE A C   1 
ATOM   352  O O   . ILE A 1 49  ? 109.743 134.730 131.283 1.00 66.92  ?  49  ILE A O   1 
ATOM   353  C CB  . ILE A 1 49  ? 111.073 132.295 133.202 1.00 66.92  ?  49  ILE A CB  1 
ATOM   354  C CG1 . ILE A 1 49  ? 112.469 132.040 133.775 1.00 66.92  ?  49  ILE A CG1 1 
ATOM   355  C CG2 . ILE A 1 49  ? 110.963 131.789 131.768 1.00 66.92  ?  49  ILE A CG2 1 
ATOM   356  C CD1 . ILE A 1 49  ? 112.811 130.575 133.951 1.00 66.92  ?  49  ILE A CD1 1 
ATOM   357  N N   . VAL A 1 50  ? 108.352 133.806 132.789 1.00 67.89  ?  50  VAL A N   1 
ATOM   358  C CA  . VAL A 1 50  ? 107.169 134.146 132.003 1.00 67.89  ?  50  VAL A CA  1 
ATOM   359  C C   . VAL A 1 50  ? 107.064 135.656 131.832 1.00 67.89  ?  50  VAL A C   1 
ATOM   360  O O   . VAL A 1 50  ? 106.679 136.151 130.766 1.00 67.89  ?  50  VAL A O   1 
ATOM   361  C CB  . VAL A 1 50  ? 105.904 133.561 132.658 1.00 67.89  ?  50  VAL A CB  1 
ATOM   362  C CG1 . VAL A 1 50  ? 104.656 134.040 131.930 1.00 67.89  ?  50  VAL A CG1 1 
ATOM   363  C CG2 . VAL A 1 50  ? 105.965 132.040 132.668 1.00 67.89  ?  50  VAL A CG2 1 
ATOM   364  N N   . LYS A 1 51  ? 107.403 136.412 132.879 1.00 70.98  ?  51  LYS A N   1 
ATOM   365  C CA  . LYS A 1 51  ? 107.369 137.867 132.779 1.00 70.98  ?  51  LYS A CA  1 
ATOM   366  C C   . LYS A 1 51  ? 108.438 138.387 131.827 1.00 70.98  ?  51  LYS A C   1 
ATOM   367  O O   . LYS A 1 51  ? 108.268 139.455 131.226 1.00 70.98  ?  51  LYS A O   1 
ATOM   368  C CB  . LYS A 1 51  ? 107.541 138.489 134.166 1.00 70.98  ?  51  LYS A CB  1 
ATOM   369  C CG  . LYS A 1 51  ? 107.646 140.010 134.172 1.00 70.98  ?  51  LYS A CG  1 
ATOM   370  C CD  . LYS A 1 51  ? 106.436 140.667 133.526 1.00 70.98  ?  51  LYS A CD  1 
ATOM   371  C CE  . LYS A 1 51  ? 106.525 142.183 133.593 1.00 70.98  ?  51  LYS A CE  1 
ATOM   372  N NZ  . LYS A 1 51  ? 107.726 142.707 132.885 1.00 70.98  1  51  LYS A NZ  1 
ATOM   373  N N   . GLN A 1 52  ? 109.541 137.654 131.676 1.00 71.34  ?  52  GLN A N   1 
ATOM   374  C CA  . GLN A 1 52  ? 110.637 138.090 130.820 1.00 71.34  ?  52  GLN A CA  1 
ATOM   375  C C   . GLN A 1 52  ? 110.468 137.646 129.374 1.00 71.34  ?  52  GLN A C   1 
ATOM   376  O O   . GLN A 1 52  ? 110.974 138.316 128.466 1.00 71.34  ?  52  GLN A O   1 
ATOM   377  C CB  . GLN A 1 52  ? 111.966 137.557 131.363 1.00 71.34  ?  52  GLN A CB  1 
ATOM   378  C CG  . GLN A 1 52  ? 113.191 138.048 130.605 1.00 71.34  ?  52  GLN A CG  1 
ATOM   379  C CD  . GLN A 1 52  ? 114.495 137.623 131.258 1.00 71.34  ?  52  GLN A CD  1 
ATOM   380  O OE1 . GLN A 1 52  ? 115.450 138.397 131.318 1.00 71.34  ?  52  GLN A OE1 1 
ATOM   381  N NE2 . GLN A 1 52  ? 114.542 136.388 131.745 1.00 71.34  ?  52  GLN A NE2 1 
ATOM   382  N N   . MET A 1 53  ? 109.769 136.535 129.136 1.00 68.53  ?  53  MET A N   1 
ATOM   383  C CA  . MET A 1 53  ? 109.533 136.037 127.781 1.00 68.53  ?  53  MET A CA  1 
ATOM   384  C C   . MET A 1 53  ? 108.315 136.752 127.192 1.00 68.53  ?  53  MET A C   1 
ATOM   385  O O   . MET A 1 53  ? 107.210 136.213 127.095 1.00 68.53  ?  53  MET A O   1 
ATOM   386  C CB  . MET A 1 53  ? 109.347 134.526 127.793 1.00 68.53  ?  53  MET A CB  1 
ATOM   387  C CG  . MET A 1 53  ? 110.592 133.756 128.207 1.00 68.53  ?  53  MET A CG  1 
ATOM   388  S SD  . MET A 1 53  ? 110.330 131.972 128.257 1.00 68.53  ?  53  MET A SD  1 
ATOM   389  C CE  . MET A 1 53  ? 111.989 131.393 128.608 1.00 68.53  ?  53  MET A CE  1 
ATOM   390  N N   . ARG A 1 54  ? 108.543 138.001 126.794 1.00 71.46  ?  54  ARG A N   1 
ATOM   391  C CA  . ARG A 1 54  ? 107.512 138.873 126.236 1.00 71.46  ?  54  ARG A CA  1 
ATOM   392  C C   . ARG A 1 54  ? 107.957 139.417 124.885 1.00 71.46  ?  54  ARG A C   1 
ATOM   393  O O   . ARG A 1 54  ? 107.855 140.611 124.599 1.00 71.46  ?  54  ARG A O   1 
ATOM   394  C CB  . ARG A 1 54  ? 107.192 140.014 127.199 1.00 71.46  ?  54  ARG A CB  1 
ATOM   395  C CG  . ARG A 1 54  ? 106.591 139.566 128.524 1.00 71.46  ?  54  ARG A CG  1 
ATOM   396  C CD  . ARG A 1 54  ? 105.070 139.520 128.471 1.00 71.46  ?  54  ARG A CD  1 
ATOM   397  N NE  . ARG A 1 54  ? 104.576 138.693 127.373 1.00 71.46  ?  54  ARG A NE  1 
ATOM   398  C CZ  . ARG A 1 54  ? 104.466 137.369 127.417 1.00 71.46  ?  54  ARG A CZ  1 
ATOM   399  N NH1 . ARG A 1 54  ? 104.820 136.700 128.507 1.00 71.46  1  54  ARG A NH1 1 
ATOM   400  N NH2 . ARG A 1 54  ? 104.005 136.709 126.363 1.00 71.46  ?  54  ARG A NH2 1 
ATOM   401  N N   . ILE A 1 55  ? 108.462 138.531 124.032 1.00 69.21  ?  55  ILE A N   1 
ATOM   402  C CA  . ILE A 1 55  ? 108.918 138.920 122.704 1.00 69.21  ?  55  ILE A CA  1 
ATOM   403  C C   . ILE A 1 55  ? 107.754 139.498 121.909 1.00 69.21  ?  55  ILE A C   1 
ATOM   404  O O   . ILE A 1 55  ? 106.975 138.759 121.306 1.00 69.21  ?  55  ILE A O   1 
ATOM   405  C CB  . ILE A 1 55  ? 109.550 137.730 121.957 1.00 69.21  ?  55  ILE A CB  1 
ATOM   406  C CG1 . ILE A 1 55  ? 110.702 137.128 122.770 1.00 69.21  ?  55  ILE A CG1 1 
ATOM   407  C CG2 . ILE A 1 55  ? 110.037 138.162 120.580 1.00 69.21  ?  55  ILE A CG2 1 
ATOM   408  C CD1 . ILE A 1 55  ? 111.822 138.102 123.085 1.00 69.21  ?  55  ILE A CD1 1 
ATOM   409  N N   . THR A 1 181 ? 91.773  130.202 140.181 1.00 63.85  ?  181 THR A N   1 
ATOM   410  C CA  . THR A 1 181 ? 91.927  128.770 140.404 1.00 63.85  ?  181 THR A CA  1 
ATOM   411  C C   . THR A 1 181 ? 92.256  128.049 139.100 1.00 63.85  ?  181 THR A C   1 
ATOM   412  O O   . THR A 1 181 ? 91.962  126.864 138.945 1.00 63.85  ?  181 THR A O   1 
ATOM   413  C CB  . THR A 1 181 ? 90.652  128.154 141.017 1.00 63.85  ?  181 THR A CB  1 
ATOM   414  O OG1 . THR A 1 181 ? 90.844  126.748 141.222 1.00 63.85  ?  181 THR A OG1 1 
ATOM   415  C CG2 . THR A 1 181 ? 89.451  128.374 140.104 1.00 63.85  ?  181 THR A CG2 1 
ATOM   416  N N   . SER A 1 182 ? 92.869  128.772 138.165 1.00 63.24  ?  182 SER A N   1 
ATOM   417  C CA  . SER A 1 182 ? 93.228  128.211 136.867 1.00 63.24  ?  182 SER A CA  1 
ATOM   418  C C   . SER A 1 182 ? 94.478  127.353 137.026 1.00 63.24  ?  182 SER A C   1 
ATOM   419  O O   . SER A 1 182 ? 95.569  127.873 137.282 1.00 63.24  ?  182 SER A O   1 
ATOM   420  C CB  . SER A 1 182 ? 93.453  129.325 135.849 1.00 63.24  ?  182 SER A CB  1 
ATOM   421  O OG  . SER A 1 182 ? 94.497  130.189 136.262 1.00 63.24  ?  182 SER A OG  1 
ATOM   422  N N   . GLY A 1 183 ? 94.322  126.040 136.875 1.00 64.03  ?  183 GLY A N   1 
ATOM   423  C CA  . GLY A 1 183 ? 95.431  125.116 136.983 1.00 64.03  ?  183 GLY A CA  1 
ATOM   424  C C   . GLY A 1 183 ? 96.341  125.054 135.780 1.00 64.03  ?  183 GLY A C   1 
ATOM   425  O O   . GLY A 1 183 ? 97.296  124.272 135.779 1.00 64.03  ?  183 GLY A O   1 
ATOM   426  N N   . ILE A 1 184 ? 96.077  125.854 134.751 1.00 62.57  ?  184 ILE A N   1 
ATOM   427  C CA  . ILE A 1 184 ? 96.887  125.878 133.539 1.00 62.57  ?  184 ILE A CA  1 
ATOM   428  C C   . ILE A 1 184 ? 96.970  127.316 133.049 1.00 62.57  ?  184 ILE A C   1 
ATOM   429  O O   . ILE A 1 184 ? 95.984  128.058 133.102 1.00 62.57  ?  184 ILE A O   1 
ATOM   430  C CB  . ILE A 1 184 ? 96.300  124.957 132.447 1.00 62.57  ?  184 ILE A CB  1 
ATOM   431  C CG1 . ILE A 1 184 ? 97.255  124.848 131.255 1.00 62.57  ?  184 ILE A CG1 1 
ATOM   432  C CG2 . ILE A 1 184 ? 94.945  125.473 131.985 1.00 62.57  ?  184 ILE A CG2 1 
ATOM   433  C CD1 . ILE A 1 184 ? 98.563  124.160 131.579 1.00 62.57  ?  184 ILE A CD1 1 
ATOM   434  N N   . PHE A 1 185 ? 98.151  127.709 132.573 1.00 62.62  ?  185 PHE A N   1 
ATOM   435  C CA  . PHE A 1 185 ? 98.387  129.061 132.073 1.00 62.62  ?  185 PHE A CA  1 
ATOM   436  C C   . PHE A 1 185 ? 99.110  128.960 130.737 1.00 62.62  ?  185 PHE A C   1 
ATOM   437  O O   . PHE A 1 185 ? 100.273 128.547 130.687 1.00 62.62  ?  185 PHE A O   1 
ATOM   438  C CB  . PHE A 1 185 ? 99.199  129.884 133.075 1.00 62.62  ?  185 PHE A CB  1 
ATOM   439  C CG  . PHE A 1 185 ? 99.263  131.348 132.745 1.00 62.62  ?  185 PHE A CG  1 
ATOM   440  C CD1 . PHE A 1 185 ? 98.273  132.212 133.180 1.00 62.62  ?  185 PHE A CD1 1 
ATOM   441  C CD2 . PHE A 1 185 ? 100.314 131.860 132.003 1.00 62.62  ?  185 PHE A CD2 1 
ATOM   442  C CE1 . PHE A 1 185 ? 98.328  133.560 132.880 1.00 62.62  ?  185 PHE A CE1 1 
ATOM   443  C CE2 . PHE A 1 185 ? 100.374 133.207 131.700 1.00 62.62  ?  185 PHE A CE2 1 
ATOM   444  C CZ  . PHE A 1 185 ? 99.380  134.058 132.139 1.00 62.62  ?  185 PHE A CZ  1 
ATOM   445  N N   . GLU A 1 186 ? 98.424  129.331 129.660 1.00 64.01  ?  186 GLU A N   1 
ATOM   446  C CA  . GLU A 1 186 ? 98.985  129.293 128.317 1.00 64.01  ?  186 GLU A CA  1 
ATOM   447  C C   . GLU A 1 186 ? 99.493  130.679 127.944 1.00 64.01  ?  186 GLU A C   1 
ATOM   448  O O   . GLU A 1 186 ? 98.807  131.680 128.176 1.00 64.01  ?  186 GLU A O   1 
ATOM   449  C CB  . GLU A 1 186 ? 97.939  128.815 127.306 1.00 64.01  ?  186 GLU A CB  1 
ATOM   450  C CG  . GLU A 1 186 ? 98.479  128.573 125.900 1.00 64.01  ?  186 GLU A CG  1 
ATOM   451  C CD  . GLU A 1 186 ? 98.621  129.847 125.085 1.00 64.01  ?  186 GLU A CD  1 
ATOM   452  O OE1 . GLU A 1 186 ? 98.010  130.871 125.460 1.00 64.01  ?  186 GLU A OE1 1 
ATOM   453  O OE2 . GLU A 1 186 ? 99.345  129.824 124.068 1.00 64.01  ?  186 GLU A OE2 1 
ATOM   454  N N   . THR A 1 187 ? 100.693 130.733 127.368 1.00 62.76  ?  187 THR A N   1 
ATOM   455  C CA  . THR A 1 187 ? 101.309 131.985 126.946 1.00 62.76  ?  187 THR A CA  1 
ATOM   456  C C   . THR A 1 187 ? 101.863 131.802 125.543 1.00 62.76  ?  187 THR A C   1 
ATOM   457  O O   . THR A 1 187 ? 102.736 130.956 125.325 1.00 62.76  ?  187 THR A O   1 
ATOM   458  C CB  . THR A 1 187 ? 102.422 132.407 127.911 1.00 62.76  ?  187 THR A CB  1 
ATOM   459  O OG1 . THR A 1 187 ? 101.898 132.494 129.242 1.00 62.76  ?  187 THR A OG1 1 
ATOM   460  C CG2 . THR A 1 187 ? 103.000 133.755 127.509 1.00 62.76  ?  187 THR A CG2 1 
ATOM   461  N N   . LYS A 1 188 ? 101.359 132.589 124.598 1.00 63.17  ?  188 LYS A N   1 
ATOM   462  C CA  . LYS A 1 188 ? 101.794 132.528 123.209 1.00 63.17  ?  188 LYS A CA  1 
ATOM   463  C C   . LYS A 1 188 ? 102.778 133.657 122.937 1.00 63.17  ?  188 LYS A C   1 
ATOM   464  O O   . LYS A 1 188 ? 102.490 134.822 123.231 1.00 63.17  ?  188 LYS A O   1 
ATOM   465  C CB  . LYS A 1 188 ? 100.598 132.629 122.261 1.00 63.17  ?  188 LYS A CB  1 
ATOM   466  C CG  . LYS A 1 188 ? 100.975 132.685 120.786 1.00 63.17  ?  188 LYS A CG  1 
ATOM   467  C CD  . LYS A 1 188 ? 99.749  132.607 119.883 1.00 63.17  ?  188 LYS A CD  1 
ATOM   468  C CE  . LYS A 1 188 ? 98.822  133.801 120.071 1.00 63.17  ?  188 LYS A CE  1 
ATOM   469  N NZ  . LYS A 1 188 ? 99.512  135.099 119.829 1.00 63.17  1  188 LYS A NZ  1 
ATOM   470  N N   . PHE A 1 189 ? 103.936 133.311 122.377 1.00 62.03  ?  189 PHE A N   1 
ATOM   471  C CA  . PHE A 1 189 ? 104.942 134.305 122.028 1.00 62.03  ?  189 PHE A CA  1 
ATOM   472  C C   . PHE A 1 189 ? 105.614 133.917 120.720 1.00 62.03  ?  189 PHE A C   1 
ATOM   473  O O   . PHE A 1 189 ? 105.897 132.740 120.484 1.00 62.03  ?  189 PHE A O   1 
ATOM   474  C CB  . PHE A 1 189 ? 105.990 134.464 123.140 1.00 62.03  ?  189 PHE A CB  1 
ATOM   475  C CG  . PHE A 1 189 ? 106.707 133.192 123.494 1.00 62.03  ?  189 PHE A CG  1 
ATOM   476  C CD1 . PHE A 1 189 ? 106.139 132.281 124.370 1.00 62.03  ?  189 PHE A CD1 1 
ATOM   477  C CD2 . PHE A 1 189 ? 107.957 132.916 122.966 1.00 62.03  ?  189 PHE A CD2 1 
ATOM   478  C CE1 . PHE A 1 189 ? 106.800 131.113 124.703 1.00 62.03  ?  189 PHE A CE1 1 
ATOM   479  C CE2 . PHE A 1 189 ? 108.623 131.750 123.296 1.00 62.03  ?  189 PHE A CE2 1 
ATOM   480  C CZ  . PHE A 1 189 ? 108.044 130.848 124.166 1.00 62.03  ?  189 PHE A CZ  1 
ATOM   481  N N   . GLN A 1 190 ? 105.862 134.912 119.874 1.00 62.74  ?  190 GLN A N   1 
ATOM   482  C CA  . GLN A 1 190 ? 106.431 134.697 118.550 1.00 62.74  ?  190 GLN A CA  1 
ATOM   483  C C   . GLN A 1 190 ? 107.909 135.064 118.558 1.00 62.74  ?  190 GLN A C   1 
ATOM   484  O O   . GLN A 1 190 ? 108.281 136.155 119.004 1.00 62.74  ?  190 GLN A O   1 
ATOM   485  C CB  . GLN A 1 190 ? 105.687 135.524 117.500 1.00 62.74  ?  190 GLN A CB  1 
ATOM   486  C CG  . GLN A 1 190 ? 106.145 135.274 116.069 1.00 62.74  ?  190 GLN A CG  1 
ATOM   487  C CD  . GLN A 1 190 ? 105.474 136.194 115.063 1.00 62.74  ?  190 GLN A CD  1 
ATOM   488  O OE1 . GLN A 1 190 ? 106.092 136.609 114.082 1.00 62.74  ?  190 GLN A OE1 1 
ATOM   489  N NE2 . GLN A 1 190 ? 104.204 136.511 115.295 1.00 62.74  ?  190 GLN A NE2 1 
ATOM   490  N N   . VAL A 1 191 ? 108.744 134.152 118.064 1.00 62.78  ?  191 VAL A N   1 
ATOM   491  C CA  . VAL A 1 191 ? 110.183 134.365 117.958 1.00 62.78  ?  191 VAL A CA  1 
ATOM   492  C C   . VAL A 1 191 ? 110.630 133.899 116.580 1.00 62.78  ?  191 VAL A C   1 
ATOM   493  O O   . VAL A 1 191 ? 110.213 132.832 116.116 1.00 62.78  ?  191 VAL A O   1 
ATOM   494  C CB  . VAL A 1 191 ? 110.961 133.614 119.057 1.00 62.78  ?  191 VAL A CB  1 
ATOM   495  C CG1 . VAL A 1 191 ? 112.463 133.722 118.812 1.00 62.78  ?  191 VAL A CG1 1 
ATOM   496  C CG2 . VAL A 1 191 ? 110.588 134.150 120.437 1.00 62.78  ?  191 VAL A CG2 1 
ATOM   497  N N   . ASP A 1 192 ? 111.469 134.700 115.923 1.00 63.93  ?  192 ASP A N   1 
ATOM   498  C CA  . ASP A 1 192 ? 111.999 134.364 114.601 1.00 63.93  ?  192 ASP A CA  1 
ATOM   499  C C   . ASP A 1 192 ? 110.882 133.964 113.639 1.00 63.93  ?  192 ASP A C   1 
ATOM   500  O O   . ASP A 1 192 ? 111.062 133.101 112.776 1.00 63.93  ?  192 ASP A O   1 
ATOM   501  C CB  . ASP A 1 192 ? 113.049 133.254 114.698 1.00 63.93  ?  192 ASP A CB  1 
ATOM   502  C CG  . ASP A 1 192 ? 113.854 133.097 113.421 1.00 63.93  ?  192 ASP A CG  1 
ATOM   503  O OD1 . ASP A 1 192 ? 113.593 133.845 112.456 1.00 63.93  ?  192 ASP A OD1 1 
ATOM   504  O OD2 . ASP A 1 192 ? 114.748 132.227 113.384 1.00 63.93  ?  192 ASP A OD2 1 
ATOM   505  N N   . LYS A 1 193 ? 109.714 134.588 113.790 1.00 63.21  ?  193 LYS A N   1 
ATOM   506  C CA  . LYS A 1 193 ? 108.573 134.368 112.904 1.00 63.21  ?  193 LYS A CA  1 
ATOM   507  C C   . LYS A 1 193 ? 107.975 132.973 113.071 1.00 63.21  ?  193 LYS A C   1 
ATOM   508  O O   . LYS A 1 193 ? 107.510 132.371 112.100 1.00 63.21  ?  193 LYS A O   1 
ATOM   509  C CB  . LYS A 1 193 ? 108.960 134.607 111.440 1.00 63.21  ?  193 LYS A CB  1 
ATOM   510  C CG  . LYS A 1 193 ? 107.782 134.852 110.503 1.00 63.21  ?  193 LYS A CG  1 
ATOM   511  C CD  . LYS A 1 193 ? 107.100 136.183 110.786 1.00 63.21  ?  193 LYS A CD  1 
ATOM   512  C CE  . LYS A 1 193 ? 105.978 136.452 109.797 1.00 63.21  ?  193 LYS A CE  1 
ATOM   513  N NZ  . LYS A 1 193 ? 105.305 137.755 110.056 1.00 63.21  1  193 LYS A NZ  1 
ATOM   514  N N   . VAL A 1 194 ? 107.981 132.441 114.291 1.00 60.87  ?  194 VAL A N   1 
ATOM   515  C CA  . VAL A 1 194 ? 107.299 131.190 114.601 1.00 60.87  ?  194 VAL A CA  1 
ATOM   516  C C   . VAL A 1 194 ? 106.764 131.282 116.022 1.00 60.87  ?  194 VAL A C   1 
ATOM   517  O O   . VAL A 1 194 ? 107.407 131.863 116.903 1.00 60.87  ?  194 VAL A O   1 
ATOM   518  C CB  . VAL A 1 194 ? 108.225 129.965 114.431 1.00 60.87  ?  194 VAL A CB  1 
ATOM   519  C CG1 . VAL A 1 194 ? 109.128 129.793 115.643 1.00 60.87  ?  194 VAL A CG1 1 
ATOM   520  C CG2 . VAL A 1 194 ? 107.403 128.705 114.189 1.00 60.87  ?  194 VAL A CG2 1 
ATOM   521  N N   . ASN A 1 195 ? 105.585 130.711 116.244 1.00 61.58  ?  195 ASN A N   1 
ATOM   522  C CA  . ASN A 1 195 ? 104.896 130.838 117.519 1.00 61.58  ?  195 ASN A CA  1 
ATOM   523  C C   . ASN A 1 195 ? 105.322 129.739 118.485 1.00 61.58  ?  195 ASN A C   1 
ATOM   524  O O   . ASN A 1 195 ? 105.750 128.655 118.080 1.00 61.58  ?  195 ASN A O   1 
ATOM   525  C CB  . ASN A 1 195 ? 103.381 130.785 117.316 1.00 61.58  ?  195 ASN A CB  1 
ATOM   526  C CG  . ASN A 1 195 ? 102.875 131.893 116.413 1.00 61.58  ?  195 ASN A CG  1 
ATOM   527  O OD1 . ASN A 1 195 ? 103.449 132.981 116.364 1.00 61.58  ?  195 ASN A OD1 1 
ATOM   528  N ND2 . ASN A 1 195 ? 101.795 131.620 115.690 1.00 61.58  ?  195 ASN A ND2 1 
ATOM   529  N N   . PHE A 1 196 ? 105.199 130.038 119.777 1.00 61.06  ?  196 PHE A N   1 
ATOM   530  C CA  . PHE A 1 196 ? 105.469 129.084 120.842 1.00 61.06  ?  196 PHE A CA  1 
ATOM   531  C C   . PHE A 1 196 ? 104.412 129.261 121.918 1.00 61.06  ?  196 PHE A C   1 
ATOM   532  O O   . PHE A 1 196 ? 104.184 130.382 122.387 1.00 61.06  ?  196 PHE A O   1 
ATOM   533  C CB  . PHE A 1 196 ? 106.866 129.288 121.440 1.00 61.06  ?  196 PHE A CB  1 
ATOM   534  C CG  . PHE A 1 196 ? 107.987 129.060 120.468 1.00 61.06  ?  196 PHE A CG  1 
ATOM   535  C CD1 . PHE A 1 196 ? 108.482 127.786 120.246 1.00 61.06  ?  196 PHE A CD1 1 
ATOM   536  C CD2 . PHE A 1 196 ? 108.554 130.122 119.784 1.00 61.06  ?  196 PHE A CD2 1 
ATOM   537  C CE1 . PHE A 1 196 ? 109.517 127.575 119.356 1.00 61.06  ?  196 PHE A CE1 1 
ATOM   538  C CE2 . PHE A 1 196 ? 109.589 129.917 118.894 1.00 61.06  ?  196 PHE A CE2 1 
ATOM   539  C CZ  . PHE A 1 196 ? 110.071 128.642 118.679 1.00 61.06  ?  196 PHE A CZ  1 
ATOM   540  N N   . HIS A 1 197 ? 103.772 128.159 122.302 1.00 62.31  ?  197 HIS A N   1 
ATOM   541  C CA  . HIS A 1 197 ? 102.725 128.149 123.320 1.00 62.31  ?  197 HIS A CA  1 
ATOM   542  C C   . HIS A 1 197 ? 103.286 127.469 124.565 1.00 62.31  ?  197 HIS A C   1 
ATOM   543  O O   . HIS A 1 197 ? 103.264 126.239 124.675 1.00 62.31  ?  197 HIS A O   1 
ATOM   544  C CB  . HIS A 1 197 ? 101.476 127.434 122.811 1.00 62.31  ?  197 HIS A CB  1 
ATOM   545  C CG  . HIS A 1 197 ? 100.861 128.074 121.605 1.00 62.31  ?  197 HIS A CG  1 
ATOM   546  N ND1 . HIS A 1 197 ? 99.757  127.550 120.967 1.00 62.31  ?  197 HIS A ND1 1 
ATOM   547  C CD2 . HIS A 1 197 ? 101.194 129.194 120.921 1.00 62.31  ?  197 HIS A CD2 1 
ATOM   548  C CE1 . HIS A 1 197 ? 99.438  128.319 119.942 1.00 62.31  ?  197 HIS A CE1 1 
ATOM   549  N NE2 . HIS A 1 197 ? 100.294 129.323 119.892 1.00 62.31  ?  197 HIS A NE2 1 
ATOM   550  N N   . MET A 1 198 ? 103.787 128.271 125.500 1.00 63.05  ?  198 MET A N   1 
ATOM   551  C CA  . MET A 1 198 ? 104.343 127.761 126.744 1.00 63.05  ?  198 MET A CA  1 
ATOM   552  C C   . MET A 1 198 ? 103.225 127.559 127.760 1.00 63.05  ?  198 MET A C   1 
ATOM   553  O O   . MET A 1 198 ? 102.376 128.438 127.944 1.00 63.05  ?  198 MET A O   1 
ATOM   554  C CB  . MET A 1 198 ? 105.396 128.724 127.294 1.00 63.05  ?  198 MET A CB  1 
ATOM   555  C CG  . MET A 1 198 ? 106.047 128.262 128.586 1.00 63.05  ?  198 MET A CG  1 
ATOM   556  S SD  . MET A 1 198 ? 107.463 129.276 129.052 1.00 63.05  ?  198 MET A SD  1 
ATOM   557  C CE  . MET A 1 198 ? 106.711 130.900 129.124 1.00 63.05  ?  198 MET A CE  1 
ATOM   558  N N   . PHE A 1 199 ? 103.230 126.401 128.416 1.00 61.39  ?  199 PHE A N   1 
ATOM   559  C CA  . PHE A 1 199 ? 102.198 126.027 129.378 1.00 61.39  ?  199 PHE A CA  1 
ATOM   560  C C   . PHE A 1 199 ? 102.826 125.956 130.765 1.00 61.39  ?  199 PHE A C   1 
ATOM   561  O O   . PHE A 1 199 ? 103.668 125.091 131.029 1.00 61.39  ?  199 PHE A O   1 
ATOM   562  C CB  . PHE A 1 199 ? 101.558 124.695 128.996 1.00 61.39  ?  199 PHE A CB  1 
ATOM   563  C CG  . PHE A 1 199 ? 100.917 124.699 127.638 1.00 61.39  ?  199 PHE A CG  1 
ATOM   564  C CD1 . PHE A 1 199 ? 99.694  125.318 127.437 1.00 61.39  ?  199 PHE A CD1 1 
ATOM   565  C CD2 . PHE A 1 199 ? 101.534 124.083 126.563 1.00 61.39  ?  199 PHE A CD2 1 
ATOM   566  C CE1 . PHE A 1 199 ? 99.101  125.324 126.189 1.00 61.39  ?  199 PHE A CE1 1 
ATOM   567  C CE2 . PHE A 1 199 ? 100.946 124.086 125.313 1.00 61.39  ?  199 PHE A CE2 1 
ATOM   568  C CZ  . PHE A 1 199 ? 99.728  124.707 125.126 1.00 61.39  ?  199 PHE A CZ  1 
ATOM   569  N N   . ASP A 1 200 ? 102.415 126.864 131.645 1.00 62.95  ?  200 ASP A N   1 
ATOM   570  C CA  . ASP A 1 200 ? 102.873 126.895 133.027 1.00 62.95  ?  200 ASP A CA  1 
ATOM   571  C C   . ASP A 1 200 ? 101.781 126.339 133.930 1.00 62.95  ?  200 ASP A C   1 
ATOM   572  O O   . ASP A 1 200 ? 100.599 126.657 133.752 1.00 62.95  ?  200 ASP A O   1 
ATOM   573  C CB  . ASP A 1 200 ? 103.236 128.320 133.449 1.00 62.95  ?  200 ASP A CB  1 
ATOM   574  C CG  . ASP A 1 200 ? 103.835 128.382 134.841 1.00 62.95  ?  200 ASP A CG  1 
ATOM   575  O OD1 . ASP A 1 200 ? 104.047 127.312 135.449 1.00 62.95  ?  200 ASP A OD1 1 
ATOM   576  O OD2 . ASP A 1 200 ? 104.094 129.503 135.327 1.00 62.95  ?  200 ASP A OD2 1 
ATOM   577  N N   . VAL A 1 201 ? 102.178 125.511 134.893 1.00 62.97  ?  201 VAL A N   1 
ATOM   578  C CA  . VAL A 1 201 ? 101.259 124.874 135.833 1.00 62.97  ?  201 VAL A CA  1 
ATOM   579  C C   . VAL A 1 201 ? 101.833 125.090 137.228 1.00 62.97  ?  201 VAL A C   1 
ATOM   580  O O   . VAL A 1 201 ? 102.745 124.369 137.650 1.00 62.97  ?  201 VAL A O   1 
ATOM   581  C CB  . VAL A 1 201 ? 101.064 123.383 135.540 1.00 62.97  ?  201 VAL A CB  1 
ATOM   582  C CG1 . VAL A 1 201 ? 100.162 122.748 136.589 1.00 62.97  ?  201 VAL A CG1 1 
ATOM   583  C CG2 . VAL A 1 201 ? 100.487 123.188 134.146 1.00 62.97  ?  201 VAL A CG2 1 
ATOM   584  N N   . GLY A 1 202 ? 101.305 126.078 137.946 1.00 64.78  ?  202 GLY A N   1 
ATOM   585  C CA  . GLY A 1 202 ? 101.759 126.369 139.292 1.00 64.78  ?  202 GLY A CA  1 
ATOM   586  C C   . GLY A 1 202 ? 100.621 126.527 140.279 1.00 64.78  ?  202 GLY A C   1 
ATOM   587  O O   . GLY A 1 202 ? 100.808 127.084 141.365 1.00 64.78  ?  202 GLY A O   1 
ATOM   588  N N   . ALA A 1 203 ? 99.436  126.042 139.915 1.00 66.05  ?  203 ALA A N   1 
ATOM   589  C CA  . ALA A 1 203 ? 98.241  126.135 140.747 1.00 66.05  ?  203 ALA A CA  1 
ATOM   590  C C   . ALA A 1 203 ? 97.555  124.779 140.841 1.00 66.05  ?  203 ALA A C   1 
ATOM   591  O O   . ALA A 1 203 ? 96.335  124.656 140.713 1.00 66.05  ?  203 ALA A O   1 
ATOM   592  C CB  . ALA A 1 203 ? 97.281  127.188 140.200 1.00 66.05  ?  203 ALA A CB  1 
ATOM   593  N N   . GLN A 1 204 ? 98.347  123.732 141.068 1.00 64.65  ?  204 GLN A N   1 
ATOM   594  C CA  . GLN A 1 204 ? 97.834  122.377 141.209 1.00 64.65  ?  204 GLN A CA  1 
ATOM   595  C C   . GLN A 1 204 ? 98.527  121.711 142.391 1.00 64.65  ?  204 GLN A C   1 
ATOM   596  O O   . GLN A 1 204 ? 99.427  122.283 143.015 1.00 64.65  ?  204 GLN A O   1 
ATOM   597  C CB  . GLN A 1 204 ? 98.037  121.570 139.920 1.00 64.65  ?  204 GLN A CB  1 
ATOM   598  C CG  . GLN A 1 204 ? 97.283  122.122 138.721 1.00 64.65  ?  204 GLN A CG  1 
ATOM   599  C CD  . GLN A 1 204 ? 97.426  121.248 137.491 1.00 64.65  ?  204 GLN A CD  1 
ATOM   600  O OE1 . GLN A 1 204 ? 98.078  120.205 137.529 1.00 64.65  ?  204 GLN A OE1 1 
ATOM   601  N NE2 . GLN A 1 204 ? 96.814  121.671 136.391 1.00 64.65  ?  204 GLN A NE2 1 
ATOM   602  N N   . ARG A 1 205 ? 98.098  120.490 142.701 1.00 68.62  ?  205 ARG A N   1 
ATOM   603  C CA  . ARG A 1 205 ? 98.664  119.756 143.819 1.00 68.62  ?  205 ARG A CA  1 
ATOM   604  C C   . ARG A 1 205 ? 100.158 119.515 143.593 1.00 68.62  ?  205 ARG A C   1 
ATOM   605  O O   . ARG A 1 205 ? 100.682 119.655 142.485 1.00 68.62  ?  205 ARG A O   1 
ATOM   606  C CB  . ARG A 1 205 ? 97.926  118.431 144.012 1.00 68.62  ?  205 ARG A CB  1 
ATOM   607  C CG  . ARG A 1 205 ? 98.206  117.745 145.340 1.00 68.62  ?  205 ARG A CG  1 
ATOM   608  C CD  . ARG A 1 205 ? 97.252  116.585 145.578 1.00 68.62  ?  205 ARG A CD  1 
ATOM   609  N NE  . ARG A 1 205 ? 97.414  115.526 144.585 1.00 68.62  ?  205 ARG A NE  1 
ATOM   610  C CZ  . ARG A 1 205 ? 98.275  114.517 144.692 1.00 68.62  ?  205 ARG A CZ  1 
ATOM   611  N NH1 . ARG A 1 205 ? 98.344  113.603 143.733 1.00 68.62  1  205 ARG A NH1 1 
ATOM   612  N NH2 . ARG A 1 205 ? 99.069  114.416 145.751 1.00 68.62  ?  205 ARG A NH2 1 
ATOM   613  N N   . ASP A 1 206 ? 100.846 119.147 144.675 1.00 69.88  ?  206 ASP A N   1 
ATOM   614  C CA  . ASP A 1 206 ? 102.289 118.935 144.607 1.00 69.88  ?  206 ASP A CA  1 
ATOM   615  C C   . ASP A 1 206 ? 102.634 117.833 143.611 1.00 69.88  ?  206 ASP A C   1 
ATOM   616  O O   . ASP A 1 206 ? 103.376 118.055 142.648 1.00 69.88  ?  206 ASP A O   1 
ATOM   617  C CB  . ASP A 1 206 ? 102.828 118.598 145.998 1.00 69.88  ?  206 ASP A CB  1 
ATOM   618  C CG  . ASP A 1 206 ? 104.340 118.483 146.027 1.00 69.88  ?  206 ASP A CG  1 
ATOM   619  O OD1 . ASP A 1 206 ? 104.983 118.772 144.996 1.00 69.88  ?  206 ASP A OD1 1 
ATOM   620  O OD2 . ASP A 1 206 ? 104.887 118.102 147.084 1.00 69.88  ?  206 ASP A OD2 1 
ATOM   621  N N   . GLU A 1 207 ? 102.104 116.633 143.831 1.00 68.40  ?  207 GLU A N   1 
ATOM   622  C CA  . GLU A 1 207 ? 102.399 115.513 142.948 1.00 68.40  ?  207 GLU A CA  1 
ATOM   623  C C   . GLU A 1 207 ? 101.842 115.773 141.554 1.00 68.40  ?  207 GLU A C   1 
ATOM   624  O O   . GLU A 1 207 ? 100.760 116.346 141.395 1.00 68.40  ?  207 GLU A O   1 
ATOM   625  C CB  . GLU A 1 207 ? 101.816 114.221 143.523 1.00 68.40  ?  207 GLU A CB  1 
ATOM   626  C CG  . GLU A 1 207 ? 101.996 112.980 142.651 1.00 68.40  ?  207 GLU A CG  1 
ATOM   627  C CD  . GLU A 1 207 ? 103.439 112.515 142.557 1.00 68.40  ?  207 GLU A CD  1 
ATOM   628  O OE1 . GLU A 1 207 ? 104.354 113.365 142.580 1.00 68.40  ?  207 GLU A OE1 1 
ATOM   629  O OE2 . GLU A 1 207 ? 103.661 111.290 142.461 1.00 68.40  ?  207 GLU A OE2 1 
ATOM   630  N N   . ARG A 1 208 ? 102.595 115.346 140.535 1.00 63.73  ?  208 ARG A N   1 
ATOM   631  C CA  . ARG A 1 208 ? 102.216 115.579 139.147 1.00 63.73  ?  208 ARG A CA  1 
ATOM   632  C C   . ARG A 1 208 ? 102.494 114.361 138.273 1.00 63.73  ?  208 ARG A C   1 
ATOM   633  O O   . ARG A 1 208 ? 102.846 114.505 137.098 1.00 63.73  ?  208 ARG A O   1 
ATOM   634  C CB  . ARG A 1 208 ? 102.946 116.799 138.579 1.00 63.73  ?  208 ARG A CB  1 
ATOM   635  C CG  . ARG A 1 208 ? 104.459 116.740 138.725 1.00 63.73  ?  208 ARG A CG  1 
ATOM   636  C CD  . ARG A 1 208 ? 105.130 117.917 138.034 1.00 63.73  ?  208 ARG A CD  1 
ATOM   637  N NE  . ARG A 1 208 ? 104.657 119.200 138.546 1.00 63.73  ?  208 ARG A NE  1 
ATOM   638  C CZ  . ARG A 1 208 ? 105.140 119.807 139.627 1.00 63.73  ?  208 ARG A CZ  1 
ATOM   639  N NH1 . ARG A 1 208 ? 106.119 119.252 140.330 1.00 63.73  1  208 ARG A NH1 1 
ATOM   640  N NH2 . ARG A 1 208 ? 104.640 120.974 140.009 1.00 63.73  ?  208 ARG A NH2 1 
ATOM   641  N N   . ARG A 1 209 ? 102.344 113.155 138.823 1.00 66.23  ?  209 ARG A N   1 
ATOM   642  C CA  . ARG A 1 209 ? 102.623 111.949 138.054 1.00 66.23  ?  209 ARG A CA  1 
ATOM   643  C C   . ARG A 1 209 ? 101.507 111.593 137.080 1.00 66.23  ?  209 ARG A C   1 
ATOM   644  O O   . ARG A 1 209 ? 101.747 110.821 136.145 1.00 66.23  ?  209 ARG A O   1 
ATOM   645  C CB  . ARG A 1 209 ? 102.873 110.765 138.993 1.00 66.23  ?  209 ARG A CB  1 
ATOM   646  C CG  . ARG A 1 209 ? 101.722 110.449 139.937 1.00 66.23  ?  209 ARG A CG  1 
ATOM   647  C CD  . ARG A 1 209 ? 101.928 109.107 140.624 1.00 66.23  ?  209 ARG A CD  1 
ATOM   648  N NE  . ARG A 1 209 ? 100.901 108.835 141.628 1.00 66.23  ?  209 ARG A NE  1 
ATOM   649  C CZ  . ARG A 1 209 ? 101.002 109.145 142.918 1.00 66.23  ?  209 ARG A CZ  1 
ATOM   650  N NH1 . ARG A 1 209 ? 102.088 109.746 143.388 1.00 66.23  1  209 ARG A NH1 1 
ATOM   651  N NH2 . ARG A 1 209 ? 100.008 108.852 143.746 1.00 66.23  ?  209 ARG A NH2 1 
ATOM   652  N N   . LYS A 1 210 ? 100.301 112.131 137.269 1.00 63.75  ?  210 LYS A N   1 
ATOM   653  C CA  . LYS A 1 210 ? 99.155  111.784 136.433 1.00 63.75  ?  210 LYS A CA  1 
ATOM   654  C C   . LYS A 1 210 ? 98.888  112.826 135.351 1.00 63.75  ?  210 LYS A C   1 
ATOM   655  O O   . LYS A 1 210 ? 98.888  112.500 134.161 1.00 63.75  ?  210 LYS A O   1 
ATOM   656  C CB  . LYS A 1 210 ? 97.908  111.592 137.307 1.00 63.75  ?  210 LYS A CB  1 
ATOM   657  C CG  . LYS A 1 210 ? 97.881  110.280 138.079 1.00 63.75  ?  210 LYS A CG  1 
ATOM   658  C CD  . LYS A 1 210 ? 97.746  109.084 137.146 1.00 63.75  ?  210 LYS A CD  1 
ATOM   659  C CE  . LYS A 1 210 ? 97.613  107.782 137.915 1.00 63.75  ?  210 LYS A CE  1 
ATOM   660  N NZ  . LYS A 1 210 ? 97.516  106.612 136.998 1.00 63.75  1  210 LYS A NZ  1 
ATOM   661  N N   . TRP A 1 211 ? 98.658  114.081 135.742 1.00 61.66  ?  211 TRP A N   1 
ATOM   662  C CA  . TRP A 1 211 ? 98.332  115.109 134.760 1.00 61.66  ?  211 TRP A CA  1 
ATOM   663  C C   . TRP A 1 211 ? 99.512  115.464 133.865 1.00 61.66  ?  211 TRP A C   1 
ATOM   664  O O   . TRP A 1 211 ? 99.327  116.206 132.894 1.00 61.66  ?  211 TRP A O   1 
ATOM   665  C CB  . TRP A 1 211 ? 97.815  116.368 135.460 1.00 61.66  ?  211 TRP A CB  1 
ATOM   666  C CG  . TRP A 1 211 ? 98.834  117.067 136.307 1.00 61.66  ?  211 TRP A CG  1 
ATOM   667  C CD1 . TRP A 1 211 ? 99.027  116.916 137.649 1.00 61.66  ?  211 TRP A CD1 1 
ATOM   668  C CD2 . TRP A 1 211 ? 99.794  118.037 135.871 1.00 61.66  ?  211 TRP A CD2 1 
ATOM   669  N NE1 . TRP A 1 211 ? 100.049 117.730 138.075 1.00 61.66  ?  211 TRP A NE1 1 
ATOM   670  C CE2 . TRP A 1 211 ? 100.537 118.428 137.002 1.00 61.66  ?  211 TRP A CE2 1 
ATOM   671  C CE3 . TRP A 1 211 ? 100.098 118.612 134.633 1.00 61.66  ?  211 TRP A CE3 1 
ATOM   672  C CZ2 . TRP A 1 211 ? 101.566 119.365 136.932 1.00 61.66  ?  211 TRP A CZ2 1 
ATOM   673  C CZ3 . TRP A 1 211 ? 101.120 119.542 134.566 1.00 61.66  ?  211 TRP A CZ3 1 
ATOM   674  C CH2 . TRP A 1 211 ? 101.841 119.909 135.708 1.00 61.66  ?  211 TRP A CH2 1 
ATOM   675  N N   . ILE A 1 212 ? 100.711 114.958 134.162 1.00 62.83  ?  212 ILE A N   1 
ATOM   676  C CA  . ILE A 1 212 ? 101.861 115.208 133.301 1.00 62.83  ?  212 ILE A CA  1 
ATOM   677  C C   . ILE A 1 212 ? 101.818 114.357 132.038 1.00 62.83  ?  212 ILE A C   1 
ATOM   678  O O   . ILE A 1 212 ? 102.461 114.708 131.040 1.00 62.83  ?  212 ILE A O   1 
ATOM   679  C CB  . ILE A 1 212 ? 103.169 114.950 134.069 1.00 62.83  ?  212 ILE A CB  1 
ATOM   680  C CG1 . ILE A 1 212 ? 104.384 115.421 133.264 1.00 62.83  ?  212 ILE A CG1 1 
ATOM   681  C CG2 . ILE A 1 212 ? 103.312 113.470 134.402 1.00 62.83  ?  212 ILE A CG2 1 
ATOM   682  C CD1 . ILE A 1 212 ? 104.411 116.910 133.004 1.00 62.83  ?  212 ILE A CD1 1 
ATOM   683  N N   . GLN A 1 213 ? 101.071 113.251 132.049 1.00 63.26  ?  213 GLN A N   1 
ATOM   684  C CA  . GLN A 1 213 ? 101.032 112.369 130.888 1.00 63.26  ?  213 GLN A CA  1 
ATOM   685  C C   . GLN A 1 213 ? 100.408 113.052 129.679 1.00 63.26  ?  213 GLN A C   1 
ATOM   686  O O   . GLN A 1 213 ? 100.817 112.792 128.542 1.00 63.26  ?  213 GLN A O   1 
ATOM   687  C CB  . GLN A 1 213 ? 100.259 111.094 131.226 1.00 63.26  ?  213 GLN A CB  1 
ATOM   688  C CG  . GLN A 1 213 ? 100.755 110.379 132.473 1.00 63.26  ?  213 GLN A CG  1 
ATOM   689  C CD  . GLN A 1 213 ? 100.006 109.089 132.741 1.00 63.26  ?  213 GLN A CD  1 
ATOM   690  O OE1 . GLN A 1 213 ? 99.147  108.682 131.959 1.00 63.26  ?  213 GLN A OE1 1 
ATOM   691  N NE2 . GLN A 1 213 ? 100.328 108.438 133.853 1.00 63.26  ?  213 GLN A NE2 1 
ATOM   692  N N   . CYS A 1 214 ? 99.422  113.924 129.900 1.00 62.51  ?  214 CYS A N   1 
ATOM   693  C CA  . CYS A 1 214 ? 98.735  114.572 128.788 1.00 62.51  ?  214 CYS A CA  1 
ATOM   694  C C   . CYS A 1 214 ? 99.654  115.488 127.992 1.00 62.51  ?  214 CYS A C   1 
ATOM   695  O O   . CYS A 1 214 ? 99.313  115.857 126.863 1.00 62.51  ?  214 CYS A O   1 
ATOM   696  C CB  . CYS A 1 214 ? 97.539  115.369 129.309 1.00 62.51  ?  214 CYS A CB  1 
ATOM   697  S SG  . CYS A 1 214 ? 96.364  114.389 130.267 1.00 62.51  ?  214 CYS A SG  1 
ATOM   698  N N   . PHE A 1 215 ? 100.810 115.859 128.546 1.00 61.41  ?  215 PHE A N   1 
ATOM   699  C CA  . PHE A 1 215 ? 101.735 116.777 127.891 1.00 61.41  ?  215 PHE A CA  1 
ATOM   700  C C   . PHE A 1 215 ? 102.771 116.059 127.034 1.00 61.41  ?  215 PHE A C   1 
ATOM   701  O O   . PHE A 1 215 ? 103.876 116.582 126.836 1.00 61.41  ?  215 PHE A O   1 
ATOM   702  C CB  . PHE A 1 215 ? 102.426 117.654 128.936 1.00 61.41  ?  215 PHE A CB  1 
ATOM   703  C CG  . PHE A 1 215 ? 101.521 118.676 129.562 1.00 61.41  ?  215 PHE A CG  1 
ATOM   704  C CD1 . PHE A 1 215 ? 101.373 119.929 128.991 1.00 61.41  ?  215 PHE A CD1 1 
ATOM   705  C CD2 . PHE A 1 215 ? 100.820 118.385 130.720 1.00 61.41  ?  215 PHE A CD2 1 
ATOM   706  C CE1 . PHE A 1 215 ? 100.542 120.872 129.564 1.00 61.41  ?  215 PHE A CE1 1 
ATOM   707  C CE2 . PHE A 1 215 ? 99.988  119.325 131.296 1.00 61.41  ?  215 PHE A CE2 1 
ATOM   708  C CZ  . PHE A 1 215 ? 99.849  120.570 130.717 1.00 61.41  ?  215 PHE A CZ  1 
ATOM   709  N N   . ASN A 1 216 ? 102.451 114.874 126.524 1.00 61.17  ?  216 ASN A N   1 
ATOM   710  C CA  . ASN A 1 216 ? 103.357 114.188 125.619 1.00 61.17  ?  216 ASN A CA  1 
ATOM   711  C C   . ASN A 1 216 ? 103.258 114.788 124.219 1.00 61.17  ?  216 ASN A C   1 
ATOM   712  O O   . ASN A 1 216 ? 102.301 115.490 123.878 1.00 61.17  ?  216 ASN A O   1 
ATOM   713  C CB  . ASN A 1 216 ? 103.046 112.692 125.572 1.00 61.17  ?  216 ASN A CB  1 
ATOM   714  C CG  . ASN A 1 216 ? 101.654 112.402 125.050 1.00 61.17  ?  216 ASN A CG  1 
ATOM   715  O OD1 . ASN A 1 216 ? 100.694 113.092 125.394 1.00 61.17  ?  216 ASN A OD1 1 
ATOM   716  N ND2 . ASN A 1 216 ? 101.537 111.380 124.210 1.00 61.17  ?  216 ASN A ND2 1 
ATOM   717  N N   . ASP A 1 217 ? 104.272 114.504 123.404 1.00 61.08  ?  217 ASP A N   1 
ATOM   718  C CA  . ASP A 1 217 ? 104.387 114.985 122.031 1.00 61.08  ?  217 ASP A CA  1 
ATOM   719  C C   . ASP A 1 217 ? 104.602 116.492 121.953 1.00 61.08  ?  217 ASP A C   1 
ATOM   720  O O   . ASP A 1 217 ? 104.584 117.056 120.851 1.00 61.08  ?  217 ASP A O   1 
ATOM   721  C CB  . ASP A 1 217 ? 103.155 114.604 121.200 1.00 61.08  ?  217 ASP A CB  1 
ATOM   722  C CG  . ASP A 1 217 ? 103.374 114.788 119.710 1.00 61.08  ?  217 ASP A CG  1 
ATOM   723  O OD1 . ASP A 1 217 ? 104.151 114.007 119.122 1.00 61.08  ?  217 ASP A OD1 1 
ATOM   724  O OD2 . ASP A 1 217 ? 102.769 115.713 119.129 1.00 61.08  ?  217 ASP A OD2 1 
ATOM   725  N N   . VAL A 1 218 ? 104.808 117.163 123.085 1.00 59.52  ?  218 VAL A N   1 
ATOM   726  C CA  . VAL A 1 218 ? 105.040 118.603 123.093 1.00 59.52  ?  218 VAL A CA  1 
ATOM   727  C C   . VAL A 1 218 ? 106.416 118.886 122.506 1.00 59.52  ?  218 VAL A C   1 
ATOM   728  O O   . VAL A 1 218 ? 107.233 117.973 122.342 1.00 59.52  ?  218 VAL A O   1 
ATOM   729  C CB  . VAL A 1 218 ? 104.916 119.189 124.512 1.00 59.52  ?  218 VAL A CB  1 
ATOM   730  C CG1 . VAL A 1 218 ? 103.506 118.987 125.050 1.00 59.52  ?  218 VAL A CG1 1 
ATOM   731  C CG2 . VAL A 1 218 ? 105.952 118.570 125.444 1.00 59.52  ?  218 VAL A CG2 1 
ATOM   732  N N   . THR A 1 219 ? 106.680 120.153 122.186 1.00 59.64  ?  219 THR A N   1 
ATOM   733  C CA  . THR A 1 219 ? 107.958 120.509 121.578 1.00 59.64  ?  219 THR A CA  1 
ATOM   734  C C   . THR A 1 219 ? 109.104 120.331 122.567 1.00 59.64  ?  219 THR A C   1 
ATOM   735  O O   . THR A 1 219 ? 110.131 119.726 122.238 1.00 59.64  ?  219 THR A O   1 
ATOM   736  C CB  . THR A 1 219 ? 107.912 121.947 121.060 1.00 59.64  ?  219 THR A CB  1 
ATOM   737  O OG1 . THR A 1 219 ? 106.797 122.103 120.172 1.00 59.64  ?  219 THR A OG1 1 
ATOM   738  C CG2 . THR A 1 219 ? 109.196 122.292 120.319 1.00 59.64  ?  219 THR A CG2 1 
ATOM   739  N N   . ALA A 1 220 ? 108.952 120.851 123.783 1.00 59.06  ?  220 ALA A N   1 
ATOM   740  C CA  . ALA A 1 220 ? 110.012 120.756 124.777 1.00 59.06  ?  220 ALA A CA  1 
ATOM   741  C C   . ALA A 1 220 ? 109.441 121.053 126.157 1.00 59.06  ?  220 ALA A C   1 
ATOM   742  O O   . ALA A 1 220 ? 108.326 121.564 126.301 1.00 59.06  ?  220 ALA A O   1 
ATOM   743  C CB  . ALA A 1 220 ? 111.167 121.708 124.450 1.00 59.06  ?  220 ALA A CB  1 
ATOM   744  N N   . ILE A 1 221 ? 110.235 120.723 127.174 1.00 58.75  ?  221 ILE A N   1 
ATOM   745  C CA  . ILE A 1 221 ? 109.889 120.949 128.572 1.00 58.75  ?  221 ILE A CA  1 
ATOM   746  C C   . ILE A 1 221 ? 110.988 121.804 129.187 1.00 58.75  ?  221 ILE A C   1 
ATOM   747  O O   . ILE A 1 221 ? 112.162 121.413 129.185 1.00 58.75  ?  221 ILE A O   1 
ATOM   748  C CB  . ILE A 1 221 ? 109.722 119.630 129.343 1.00 58.75  ?  221 ILE A CB  1 
ATOM   749  C CG1 . ILE A 1 221 ? 108.674 118.747 128.661 1.00 58.75  ?  221 ILE A CG1 1 
ATOM   750  C CG2 . ILE A 1 221 ? 109.328 119.907 130.791 1.00 58.75  ?  221 ILE A CG2 1 
ATOM   751  C CD1 . ILE A 1 221 ? 108.514 117.381 129.292 1.00 58.75  ?  221 ILE A CD1 1 
ATOM   752  N N   . ILE A 1 222 ? 110.607 122.964 129.707 1.00 59.52  ?  222 ILE A N   1 
ATOM   753  C CA  . ILE A 1 222 ? 111.532 123.908 130.323 1.00 59.52  ?  222 ILE A CA  1 
ATOM   754  C C   . ILE A 1 222 ? 111.386 123.776 131.833 1.00 59.52  ?  222 ILE A C   1 
ATOM   755  O O   . ILE A 1 222 ? 110.369 124.182 132.407 1.00 59.52  ?  222 ILE A O   1 
ATOM   756  C CB  . ILE A 1 222 ? 111.260 125.345 129.860 1.00 59.52  ?  222 ILE A CB  1 
ATOM   757  C CG1 . ILE A 1 222 ? 111.261 125.419 128.331 1.00 59.52  ?  222 ILE A CG1 1 
ATOM   758  C CG2 . ILE A 1 222 ? 112.300 126.296 130.441 1.00 59.52  ?  222 ILE A CG2 1 
ATOM   759  C CD1 . ILE A 1 222 ? 110.858 126.767 127.786 1.00 59.52  ?  222 ILE A CD1 1 
ATOM   760  N N   . PHE A 1 223 ? 112.402 123.210 132.479 1.00 59.88  ?  223 PHE A N   1 
ATOM   761  C CA  . PHE A 1 223 ? 112.426 123.048 133.926 1.00 59.88  ?  223 PHE A CA  1 
ATOM   762  C C   . PHE A 1 223 ? 113.193 124.206 134.550 1.00 59.88  ?  223 PHE A C   1 
ATOM   763  O O   . PHE A 1 223 ? 114.321 124.501 134.141 1.00 59.88  ?  223 PHE A O   1 
ATOM   764  C CB  . PHE A 1 223 ? 113.070 121.715 134.311 1.00 59.88  ?  223 PHE A CB  1 
ATOM   765  C CG  . PHE A 1 223 ? 113.083 121.450 135.790 1.00 59.88  ?  223 PHE A CG  1 
ATOM   766  C CD1 . PHE A 1 223 ? 114.180 121.799 136.560 1.00 59.88  ?  223 PHE A CD1 1 
ATOM   767  C CD2 . PHE A 1 223 ? 111.999 120.851 136.409 1.00 59.88  ?  223 PHE A CD2 1 
ATOM   768  C CE1 . PHE A 1 223 ? 114.195 121.556 137.921 1.00 59.88  ?  223 PHE A CE1 1 
ATOM   769  C CE2 . PHE A 1 223 ? 112.008 120.605 137.769 1.00 59.88  ?  223 PHE A CE2 1 
ATOM   770  C CZ  . PHE A 1 223 ? 113.108 120.958 138.525 1.00 59.88  ?  223 PHE A CZ  1 
ATOM   771  N N   . VAL A 1 224 ? 112.579 124.862 135.532 1.00 62.54  ?  224 VAL A N   1 
ATOM   772  C CA  . VAL A 1 224 ? 113.175 125.997 136.225 1.00 62.54  ?  224 VAL A CA  1 
ATOM   773  C C   . VAL A 1 224 ? 113.667 125.527 137.586 1.00 62.54  ?  224 VAL A C   1 
ATOM   774  O O   . VAL A 1 224 ? 113.025 124.693 138.236 1.00 62.54  ?  224 VAL A O   1 
ATOM   775  C CB  . VAL A 1 224 ? 112.169 127.157 136.371 1.00 62.54  ?  224 VAL A CB  1 
ATOM   776  C CG1 . VAL A 1 224 ? 112.866 128.422 136.862 1.00 62.54  ?  224 VAL A CG1 1 
ATOM   777  C CG2 . VAL A 1 224 ? 111.458 127.414 135.050 1.00 62.54  ?  224 VAL A CG2 1 
ATOM   778  N N   . VAL A 1 225 ? 114.807 126.062 138.014 1.00 63.43  ?  225 VAL A N   1 
ATOM   779  C CA  . VAL A 1 225 ? 115.412 125.691 139.289 1.00 63.43  ?  225 VAL A CA  1 
ATOM   780  C C   . VAL A 1 225 ? 116.138 126.904 139.850 1.00 63.43  ?  225 VAL A C   1 
ATOM   781  O O   . VAL A 1 225 ? 116.769 127.664 139.110 1.00 63.43  ?  225 VAL A O   1 
ATOM   782  C CB  . VAL A 1 225 ? 116.372 124.493 139.133 1.00 63.43  ?  225 VAL A CB  1 
ATOM   783  C CG1 . VAL A 1 225 ? 117.344 124.735 137.989 1.00 63.43  ?  225 VAL A CG1 1 
ATOM   784  C CG2 . VAL A 1 225 ? 117.127 124.245 140.430 1.00 63.43  ?  225 VAL A CG2 1 
ATOM   785  N N   . ASP A 1 226 ? 116.044 127.081 141.166 1.00 67.47  ?  226 ASP A N   1 
ATOM   786  C CA  . ASP A 1 226 ? 116.724 128.173 141.861 1.00 67.47  ?  226 ASP A CA  1 
ATOM   787  C C   . ASP A 1 226 ? 118.161 127.741 142.125 1.00 67.47  ?  226 ASP A C   1 
ATOM   788  O O   . ASP A 1 226 ? 118.474 127.123 143.143 1.00 67.47  ?  226 ASP A O   1 
ATOM   789  C CB  . ASP A 1 226 ? 115.997 128.524 143.153 1.00 67.47  ?  226 ASP A CB  1 
ATOM   790  C CG  . ASP A 1 226 ? 116.607 129.719 143.862 1.00 67.47  ?  226 ASP A CG  1 
ATOM   791  O OD1 . ASP A 1 226 ? 117.593 130.283 143.344 1.00 67.47  ?  226 ASP A OD1 1 
ATOM   792  O OD2 . ASP A 1 226 ? 116.098 130.095 144.939 1.00 67.47  ?  226 ASP A OD2 1 
ATOM   793  N N   . SER A 1 227 ? 119.049 128.072 141.186 1.00 67.50  ?  227 SER A N   1 
ATOM   794  C CA  . SER A 1 227 ? 120.451 127.692 141.306 1.00 67.50  ?  227 SER A CA  1 
ATOM   795  C C   . SER A 1 227 ? 121.169 128.423 142.432 1.00 67.50  ?  227 SER A C   1 
ATOM   796  O O   . SER A 1 227 ? 122.280 128.023 142.795 1.00 67.50  ?  227 SER A O   1 
ATOM   797  C CB  . SER A 1 227 ? 121.176 127.951 139.984 1.00 67.50  ?  227 SER A CB  1 
ATOM   798  O OG  . SER A 1 227 ? 121.111 129.320 139.627 1.00 67.50  ?  227 SER A OG  1 
ATOM   799  N N   . SER A 1 228 ? 120.570 129.475 142.990 1.00 68.40  ?  228 SER A N   1 
ATOM   800  C CA  . SER A 1 228 ? 121.195 130.230 144.070 1.00 68.40  ?  228 SER A CA  1 
ATOM   801  C C   . SER A 1 228 ? 120.906 129.612 145.434 1.00 68.40  ?  228 SER A C   1 
ATOM   802  O O   . SER A 1 228 ? 121.825 129.412 146.235 1.00 68.40  ?  228 SER A O   1 
ATOM   803  C CB  . SER A 1 228 ? 120.715 131.684 144.037 1.00 68.40  ?  228 SER A CB  1 
ATOM   804  O OG  . SER A 1 228 ? 119.310 131.763 144.204 1.00 68.40  ?  228 SER A OG  1 
ATOM   805  N N   . ASP A 1 229 ? 119.642 129.306 145.712 1.00 68.25  ?  229 ASP A N   1 
ATOM   806  C CA  . ASP A 1 229 ? 119.249 128.717 146.990 1.00 68.25  ?  229 ASP A CA  1 
ATOM   807  C C   . ASP A 1 229 ? 119.715 127.267 147.025 1.00 68.25  ?  229 ASP A C   1 
ATOM   808  O O   . ASP A 1 229 ? 119.111 126.390 146.405 1.00 68.25  ?  229 ASP A O   1 
ATOM   809  C CB  . ASP A 1 229 ? 117.740 128.818 147.178 1.00 68.25  ?  229 ASP A CB  1 
ATOM   810  C CG  . ASP A 1 229 ? 117.300 128.462 148.586 1.00 68.25  ?  229 ASP A CG  1 
ATOM   811  O OD1 . ASP A 1 229 ? 118.002 127.675 149.254 1.00 68.25  ?  229 ASP A OD1 1 
ATOM   812  O OD2 . ASP A 1 229 ? 116.248 128.972 149.026 1.00 68.25  ?  229 ASP A OD2 1 
ATOM   813  N N   . TYR A 1 230 ? 120.801 127.009 147.758 1.00 69.17  ?  230 TYR A N   1 
ATOM   814  C CA  . TYR A 1 230 ? 121.334 125.656 147.852 1.00 69.17  ?  230 TYR A CA  1 
ATOM   815  C C   . TYR A 1 230 ? 120.425 124.728 148.647 1.00 69.17  ?  230 TYR A C   1 
ATOM   816  O O   . TYR A 1 230 ? 120.474 123.510 148.443 1.00 69.17  ?  230 TYR A O   1 
ATOM   817  C CB  . TYR A 1 230 ? 122.724 125.683 148.491 1.00 69.17  ?  230 TYR A CB  1 
ATOM   818  C CG  . TYR A 1 230 ? 123.719 126.573 147.777 1.00 69.17  ?  230 TYR A CG  1 
ATOM   819  C CD1 . TYR A 1 230 ? 123.612 126.820 146.414 1.00 69.17  ?  230 TYR A CD1 1 
ATOM   820  C CD2 . TYR A 1 230 ? 124.766 127.169 148.469 1.00 69.17  ?  230 TYR A CD2 1 
ATOM   821  C CE1 . TYR A 1 230 ? 124.519 127.632 145.761 1.00 69.17  ?  230 TYR A CE1 1 
ATOM   822  C CE2 . TYR A 1 230 ? 125.677 127.983 147.824 1.00 69.17  ?  230 TYR A CE2 1 
ATOM   823  C CZ  . TYR A 1 230 ? 125.549 128.212 146.471 1.00 69.17  ?  230 TYR A CZ  1 
ATOM   824  O OH  . TYR A 1 230 ? 126.455 129.022 145.825 1.00 69.17  ?  230 TYR A OH  1 
ATOM   825  N N   . ASN A 1 231 ? 119.601 125.271 149.546 1.00 68.74  ?  231 ASN A N   1 
ATOM   826  C CA  . ASN A 1 231 ? 118.728 124.426 150.355 1.00 68.74  ?  231 ASN A CA  1 
ATOM   827  C C   . ASN A 1 231 ? 117.725 123.681 149.483 1.00 68.74  ?  231 ASN A C   1 
ATOM   828  O O   . ASN A 1 231 ? 117.551 122.464 149.616 1.00 68.74  ?  231 ASN A O   1 
ATOM   829  C CB  . ASN A 1 231 ? 118.006 125.274 151.402 1.00 68.74  ?  231 ASN A CB  1 
ATOM   830  C CG  . ASN A 1 231 ? 118.964 125.996 152.329 1.00 68.74  ?  231 ASN A CG  1 
ATOM   831  O OD1 . ASN A 1 231 ? 119.351 125.471 153.373 1.00 68.74  ?  231 ASN A OD1 1 
ATOM   832  N ND2 . ASN A 1 231 ? 119.352 127.209 151.952 1.00 68.74  ?  231 ASN A ND2 1 
ATOM   833  N N   . ARG A 1 232 ? 117.056 124.396 148.582 1.00 67.39  ?  232 ARG A N   1 
ATOM   834  C CA  . ARG A 1 232 ? 116.062 123.803 147.699 1.00 67.39  ?  232 ARG A CA  1 
ATOM   835  C C   . ARG A 1 232 ? 116.676 123.133 146.477 1.00 67.39  ?  232 ARG A C   1 
ATOM   836  O O   . ARG A 1 232 ? 115.935 122.604 145.642 1.00 67.39  ?  232 ARG A O   1 
ATOM   837  C CB  . ARG A 1 232 ? 115.061 124.871 147.242 1.00 67.39  ?  232 ARG A CB  1 
ATOM   838  C CG  . ARG A 1 232 ? 114.241 125.488 148.367 1.00 67.39  ?  232 ARG A CG  1 
ATOM   839  C CD  . ARG A 1 232 ? 113.339 124.465 149.043 1.00 67.39  ?  232 ARG A CD  1 
ATOM   840  N NE  . ARG A 1 232 ? 112.473 123.776 148.089 1.00 67.39  ?  232 ARG A NE  1 
ATOM   841  C CZ  . ARG A 1 232 ? 111.315 124.253 147.640 1.00 67.39  ?  232 ARG A CZ  1 
ATOM   842  N NH1 . ARG A 1 232 ? 110.869 125.434 148.050 1.00 67.39  1  232 ARG A NH1 1 
ATOM   843  N NH2 . ARG A 1 232 ? 110.602 123.548 146.773 1.00 67.39  ?  232 ARG A NH2 1 
ATOM   844  N N   . LEU A 1 233 ? 118.004 123.142 146.348 1.00 67.11  ?  233 LEU A N   1 
ATOM   845  C CA  . LEU A 1 233 ? 118.633 122.518 145.189 1.00 67.11  ?  233 LEU A CA  1 
ATOM   846  C C   . LEU A 1 233 ? 118.413 121.010 145.192 1.00 67.11  ?  233 LEU A C   1 
ATOM   847  O O   . LEU A 1 233 ? 118.244 120.400 144.129 1.00 67.11  ?  233 LEU A O   1 
ATOM   848  C CB  . LEU A 1 233 ? 120.126 122.850 145.164 1.00 67.11  ?  233 LEU A CB  1 
ATOM   849  C CG  . LEU A 1 233 ? 120.853 122.637 143.834 1.00 67.11  ?  233 LEU A CG  1 
ATOM   850  C CD1 . LEU A 1 233 ? 121.974 123.653 143.682 1.00 67.11  ?  233 LEU A CD1 1 
ATOM   851  C CD2 . LEU A 1 233 ? 121.408 121.226 143.722 1.00 67.11  ?  233 LEU A CD2 1 
ATOM   852  N N   . GLN A 1 234 ? 118.406 120.392 146.374 1.00 64.22  ?  234 GLN A N   1 
ATOM   853  C CA  . GLN A 1 234 ? 118.178 118.952 146.455 1.00 64.22  ?  234 GLN A CA  1 
ATOM   854  C C   . GLN A 1 234 ? 116.788 118.592 145.944 1.00 64.22  ?  234 GLN A C   1 
ATOM   855  O O   . GLN A 1 234 ? 116.628 117.667 145.138 1.00 64.22  ?  234 GLN A O   1 
ATOM   856  C CB  . GLN A 1 234 ? 118.365 118.475 147.896 1.00 64.22  ?  234 GLN A CB  1 
ATOM   857  C CG  . GLN A 1 234 ? 118.189 116.972 148.087 1.00 64.22  ?  234 GLN A CG  1 
ATOM   858  C CD  . GLN A 1 234 ? 119.123 116.148 147.219 1.00 64.22  ?  234 GLN A CD  1 
ATOM   859  O OE1 . GLN A 1 234 ? 118.743 115.094 146.708 1.00 64.22  ?  234 GLN A OE1 1 
ATOM   860  N NE2 . GLN A 1 234 ? 120.355 116.619 147.053 1.00 64.22  ?  234 GLN A NE2 1 
ATOM   861  N N   . GLU A 1 235 ? 115.764 119.313 146.408 1.00 65.12  ?  235 GLU A N   1 
ATOM   862  C CA  . GLU A 1 235 ? 114.407 119.046 145.945 1.00 65.12  ?  235 GLU A CA  1 
ATOM   863  C C   . GLU A 1 235 ? 114.270 119.333 144.456 1.00 65.12  ?  235 GLU A C   1 
ATOM   864  O O   . GLU A 1 235 ? 113.544 118.630 143.743 1.00 65.12  ?  235 GLU A O   1 
ATOM   865  C CB  . GLU A 1 235 ? 113.407 119.882 146.745 1.00 65.12  ?  235 GLU A CB  1 
ATOM   866  C CG  . GLU A 1 235 ? 113.410 119.595 148.239 1.00 65.12  ?  235 GLU A CG  1 
ATOM   867  C CD  . GLU A 1 235 ? 112.941 118.190 148.567 1.00 65.12  ?  235 GLU A CD  1 
ATOM   868  O OE1 . GLU A 1 235 ? 112.437 117.500 147.656 1.00 65.12  ?  235 GLU A OE1 1 
ATOM   869  O OE2 . GLU A 1 235 ? 113.076 117.775 149.737 1.00 65.12  ?  235 GLU A OE2 1 
ATOM   870  N N   . ALA A 1 236 ? 114.966 120.361 143.964 1.00 62.68  ?  236 ALA A N   1 
ATOM   871  C CA  . ALA A 1 236 ? 114.925 120.660 142.537 1.00 62.68  ?  236 ALA A CA  1 
ATOM   872  C C   . ALA A 1 236 ? 115.515 119.517 141.722 1.00 62.68  ?  236 ALA A C   1 
ATOM   873  O O   . ALA A 1 236 ? 114.943 119.112 140.703 1.00 62.68  ?  236 ALA A O   1 
ATOM   874  C CB  . ALA A 1 236 ? 115.670 121.963 142.253 1.00 62.68  ?  236 ALA A CB  1 
ATOM   875  N N   . LEU A 1 237 ? 116.660 118.985 142.154 1.00 64.26  ?  237 LEU A N   1 
ATOM   876  C CA  . LEU A 1 237 ? 117.258 117.855 141.450 1.00 64.26  ?  237 LEU A CA  1 
ATOM   877  C C   . LEU A 1 237 ? 116.364 116.624 141.528 1.00 64.26  ?  237 LEU A C   1 
ATOM   878  O O   . LEU A 1 237 ? 116.251 115.868 140.557 1.00 64.26  ?  237 LEU A O   1 
ATOM   879  C CB  . LEU A 1 237 ? 118.642 117.551 142.023 1.00 64.26  ?  237 LEU A CB  1 
ATOM   880  C CG  . LEU A 1 237 ? 119.819 118.221 141.310 1.00 64.26  ?  237 LEU A CG  1 
ATOM   881  C CD1 . LEU A 1 237 ? 119.622 119.727 141.220 1.00 64.26  ?  237 LEU A CD1 1 
ATOM   882  C CD2 . LEU A 1 237 ? 121.126 117.892 142.015 1.00 64.26  ?  237 LEU A CD2 1 
ATOM   883  N N   . ASN A 1 238 ? 115.722 116.403 142.677 1.00 62.56  ?  238 ASN A N   1 
ATOM   884  C CA  . ASN A 1 238 ? 114.804 115.276 142.802 1.00 62.56  ?  238 ASN A CA  1 
ATOM   885  C C   . ASN A 1 238 ? 113.647 115.406 141.818 1.00 62.56  ?  238 ASN A C   1 
ATOM   886  O O   . ASN A 1 238 ? 113.285 114.443 141.132 1.00 62.56  ?  238 ASN A O   1 
ATOM   887  C CB  . ASN A 1 238 ? 114.283 115.179 144.236 1.00 62.56  ?  238 ASN A CB  1 
ATOM   888  C CG  . ASN A 1 238 ? 115.373 114.829 145.231 1.00 62.56  ?  238 ASN A CG  1 
ATOM   889  O OD1 . ASN A 1 238 ? 115.590 115.545 146.209 1.00 62.56  ?  238 ASN A OD1 1 
ATOM   890  N ND2 . ASN A 1 238 ? 116.064 113.721 144.987 1.00 62.56  ?  238 ASN A ND2 1 
ATOM   891  N N   . ASP A 1 239 ? 113.053 116.599 141.735 1.00 61.41  ?  239 ASP A N   1 
ATOM   892  C CA  . ASP A 1 239 ? 111.947 116.812 140.809 1.00 61.41  ?  239 ASP A CA  1 
ATOM   893  C C   . ASP A 1 239 ? 112.405 116.661 139.363 1.00 61.41  ?  239 ASP A C   1 
ATOM   894  O O   . ASP A 1 239 ? 111.679 116.109 138.528 1.00 61.41  ?  239 ASP A O   1 
ATOM   895  C CB  . ASP A 1 239 ? 111.335 118.195 141.035 1.00 61.41  ?  239 ASP A CB  1 
ATOM   896  C CG  . ASP A 1 239 ? 110.082 118.422 140.210 1.00 61.41  ?  239 ASP A CG  1 
ATOM   897  O OD1 . ASP A 1 239 ? 109.617 117.467 139.554 1.00 61.41  ?  239 ASP A OD1 1 
ATOM   898  O OD2 . ASP A 1 239 ? 109.563 119.558 140.218 1.00 61.41  ?  239 ASP A OD2 1 
ATOM   899  N N   . PHE A 1 240 ? 113.609 117.144 139.049 1.00 59.64  ?  240 PHE A N   1 
ATOM   900  C CA  . PHE A 1 240 ? 114.125 117.005 137.692 1.00 59.64  ?  240 PHE A CA  1 
ATOM   901  C C   . PHE A 1 240 ? 114.333 115.539 137.334 1.00 59.64  ?  240 PHE A C   1 
ATOM   902  O O   . PHE A 1 240 ? 113.992 115.107 136.227 1.00 59.64  ?  240 PHE A O   1 
ATOM   903  C CB  . PHE A 1 240 ? 115.433 117.784 137.548 1.00 59.64  ?  240 PHE A CB  1 
ATOM   904  C CG  . PHE A 1 240 ? 116.006 117.755 136.160 1.00 59.64  ?  240 PHE A CG  1 
ATOM   905  C CD1 . PHE A 1 240 ? 115.638 118.707 135.224 1.00 59.64  ?  240 PHE A CD1 1 
ATOM   906  C CD2 . PHE A 1 240 ? 116.915 116.777 135.791 1.00 59.64  ?  240 PHE A CD2 1 
ATOM   907  C CE1 . PHE A 1 240 ? 116.165 118.684 133.947 1.00 59.64  ?  240 PHE A CE1 1 
ATOM   908  C CE2 . PHE A 1 240 ? 117.444 116.749 134.516 1.00 59.64  ?  240 PHE A CE2 1 
ATOM   909  C CZ  . PHE A 1 240 ? 117.069 117.703 133.593 1.00 59.64  ?  240 PHE A CZ  1 
ATOM   910  N N   . LYS A 1 241 ? 114.889 114.756 138.262 1.00 59.24  ?  241 LYS A N   1 
ATOM   911  C CA  . LYS A 1 241 ? 115.079 113.332 138.008 1.00 59.24  ?  241 LYS A CA  1 
ATOM   912  C C   . LYS A 1 241 ? 113.741 112.618 137.862 1.00 59.24  ?  241 LYS A C   1 
ATOM   913  O O   . LYS A 1 241 ? 113.603 111.709 137.035 1.00 59.24  ?  241 LYS A O   1 
ATOM   914  C CB  . LYS A 1 241 ? 115.901 112.705 139.134 1.00 59.24  ?  241 LYS A CB  1 
ATOM   915  C CG  . LYS A 1 241 ? 116.136 111.212 138.974 1.00 59.24  ?  241 LYS A CG  1 
ATOM   916  C CD  . LYS A 1 241 ? 116.946 110.653 140.132 1.00 59.24  ?  241 LYS A CD  1 
ATOM   917  C CE  . LYS A 1 241 ? 117.174 109.158 139.975 1.00 59.24  ?  241 LYS A CE  1 
ATOM   918  N NZ  . LYS A 1 241 ? 117.961 108.594 141.106 1.00 59.24  1  241 LYS A NZ  1 
ATOM   919  N N   . SER A 1 242 ? 112.744 113.014 138.656 1.00 60.53  ?  242 SER A N   1 
ATOM   920  C CA  . SER A 1 242 ? 111.424 112.402 138.538 1.00 60.53  ?  242 SER A CA  1 
ATOM   921  C C   . SER A 1 242 ? 110.792 112.715 137.188 1.00 60.53  ?  242 SER A C   1 
ATOM   922  O O   . SER A 1 242 ? 110.195 111.835 136.556 1.00 60.53  ?  242 SER A O   1 
ATOM   923  C CB  . SER A 1 242 ? 110.523 112.881 139.676 1.00 60.53  ?  242 SER A CB  1 
ATOM   924  O OG  . SER A 1 242 ? 111.064 112.529 140.937 1.00 60.53  ?  242 SER A OG  1 
ATOM   925  N N   . ILE A 1 243 ? 110.911 113.964 136.729 1.00 60.39  ?  243 ILE A N   1 
ATOM   926  C CA  . ILE A 1 243 ? 110.344 114.342 135.441 1.00 60.39  ?  243 ILE A CA  1 
ATOM   927  C C   . ILE A 1 243 ? 111.124 113.733 134.283 1.00 60.39  ?  243 ILE A C   1 
ATOM   928  O O   . ILE A 1 243 ? 110.563 113.536 133.199 1.00 60.39  ?  243 ILE A O   1 
ATOM   929  C CB  . ILE A 1 243 ? 110.296 115.876 135.308 1.00 60.39  ?  243 ILE A CB  1 
ATOM   930  C CG1 . ILE A 1 243 ? 109.370 116.473 136.372 1.00 60.39  ?  243 ILE A CG1 1 
ATOM   931  C CG2 . ILE A 1 243 ? 109.836 116.274 133.910 1.00 60.39  ?  243 ILE A CG2 1 
ATOM   932  C CD1 . ILE A 1 243 ? 109.501 117.976 136.531 1.00 60.39  ?  243 ILE A CD1 1 
ATOM   933  N N   . TRP A 1 244 ? 112.406 113.425 134.484 1.00 59.72  ?  244 TRP A N   1 
ATOM   934  C CA  . TRP A 1 244 ? 113.218 112.872 133.405 1.00 59.72  ?  244 TRP A CA  1 
ATOM   935  C C   . TRP A 1 244 ? 112.974 111.376 133.238 1.00 59.72  ?  244 TRP A C   1 
ATOM   936  O O   . TRP A 1 244 ? 112.824 110.886 132.113 1.00 59.72  ?  244 TRP A O   1 
ATOM   937  C CB  . TRP A 1 244 ? 114.699 113.146 133.675 1.00 59.72  ?  244 TRP A CB  1 
ATOM   938  C CG  . TRP A 1 244 ? 115.608 112.650 132.593 1.00 59.72  ?  244 TRP A CG  1 
ATOM   939  C CD1 . TRP A 1 244 ? 116.197 111.422 132.516 1.00 59.72  ?  244 TRP A CD1 1 
ATOM   940  C CD2 . TRP A 1 244 ? 116.033 113.373 131.432 1.00 59.72  ?  244 TRP A CD2 1 
ATOM   941  N NE1 . TRP A 1 244 ? 116.962 111.335 131.378 1.00 59.72  ?  244 TRP A NE1 1 
ATOM   942  C CE2 . TRP A 1 244 ? 116.878 112.520 130.695 1.00 59.72  ?  244 TRP A CE2 1 
ATOM   943  C CE3 . TRP A 1 244 ? 115.780 114.659 130.943 1.00 59.72  ?  244 TRP A CE3 1 
ATOM   944  C CZ2 . TRP A 1 244 ? 117.472 112.910 129.497 1.00 59.72  ?  244 TRP A CZ2 1 
ATOM   945  C CZ3 . TRP A 1 244 ? 116.371 115.044 129.753 1.00 59.72  ?  244 TRP A CZ3 1 
ATOM   946  C CH2 . TRP A 1 244 ? 117.207 114.173 129.044 1.00 59.72  ?  244 TRP A CH2 1 
ATOM   947  N N   . ASN A 1 245 ? 112.931 110.637 134.345 1.00 59.64  ?  245 ASN A N   1 
ATOM   948  C CA  . ASN A 1 245 ? 112.725 109.195 134.310 1.00 59.64  ?  245 ASN A CA  1 
ATOM   949  C C   . ASN A 1 245 ? 111.258 108.806 134.161 1.00 59.64  ?  245 ASN A C   1 
ATOM   950  O O   . ASN A 1 245 ? 110.926 107.629 134.337 1.00 59.64  ?  245 ASN A O   1 
ATOM   951  C CB  . ASN A 1 245 ? 113.302 108.555 135.575 1.00 59.64  ?  245 ASN A CB  1 
ATOM   952  C CG  . ASN A 1 245 ? 114.802 108.740 135.690 1.00 59.64  ?  245 ASN A CG  1 
ATOM   953  O OD1 . ASN A 1 245 ? 115.579 107.903 135.230 1.00 59.64  ?  245 ASN A OD1 1 
ATOM   954  N ND2 . ASN A 1 245 ? 115.217 109.841 136.305 1.00 59.64  ?  245 ASN A ND2 1 
ATOM   955  N N   . ASN A 1 246 ? 110.380 109.755 133.845 1.00 62.84  ?  246 ASN A N   1 
ATOM   956  C CA  . ASN A 1 246 ? 108.971 109.433 133.670 1.00 62.84  ?  246 ASN A CA  1 
ATOM   957  C C   . ASN A 1 246 ? 108.782 108.508 132.474 1.00 62.84  ?  246 ASN A C   1 
ATOM   958  O O   . ASN A 1 246 ? 109.450 108.648 131.446 1.00 62.84  ?  246 ASN A O   1 
ATOM   959  C CB  . ASN A 1 246 ? 108.156 110.713 133.481 1.00 62.84  ?  246 ASN A CB  1 
ATOM   960  C CG  . ASN A 1 246 ? 106.675 110.442 133.306 1.00 62.84  ?  246 ASN A CG  1 
ATOM   961  O OD1 . ASN A 1 246 ? 106.195 110.254 132.188 1.00 62.84  ?  246 ASN A OD1 1 
ATOM   962  N ND2 . ASN A 1 246 ? 105.942 110.420 134.413 1.00 62.84  ?  246 ASN A ND2 1 
ATOM   963  N N   . ARG A 1 247 ? 107.860 107.554 132.615 1.00 65.30  ?  247 ARG A N   1 
ATOM   964  C CA  . ARG A 1 247 ? 107.630 106.586 131.548 1.00 65.30  ?  247 ARG A CA  1 
ATOM   965  C C   . ARG A 1 247 ? 106.949 107.224 130.344 1.00 65.30  ?  247 ARG A C   1 
ATOM   966  O O   . ARG A 1 247 ? 107.223 106.835 129.203 1.00 65.30  ?  247 ARG A O   1 
ATOM   967  C CB  . ARG A 1 247 ? 106.792 105.420 132.074 1.00 65.30  ?  247 ARG A CB  1 
ATOM   968  C CG  . ARG A 1 247 ? 106.489 104.351 131.035 1.00 65.30  ?  247 ARG A CG  1 
ATOM   969  C CD  . ARG A 1 247 ? 105.792 103.152 131.658 1.00 65.30  ?  247 ARG A CD  1 
ATOM   970  N NE  . ARG A 1 247 ? 104.537 103.521 132.308 1.00 65.30  ?  247 ARG A NE  1 
ATOM   971  C CZ  . ARG A 1 247 ? 103.367 103.631 131.684 1.00 65.30  ?  247 ARG A CZ  1 
ATOM   972  N NH1 . ARG A 1 247 ? 102.283 103.972 132.368 1.00 65.30  1  247 ARG A NH1 1 
ATOM   973  N NH2 . ARG A 1 247 ? 103.275 103.406 130.380 1.00 65.30  ?  247 ARG A NH2 1 
ATOM   974  N N   . TRP A 1 248 ? 106.066 108.198 130.571 1.00 62.52  ?  248 TRP A N   1 
ATOM   975  C CA  . TRP A 1 248 ? 105.351 108.824 129.464 1.00 62.52  ?  248 TRP A CA  1 
ATOM   976  C C   . TRP A 1 248 ? 106.188 109.911 128.800 1.00 62.52  ?  248 TRP A C   1 
ATOM   977  O O   . TRP A 1 248 ? 106.175 110.042 127.571 1.00 62.52  ?  248 TRP A O   1 
ATOM   978  C CB  . TRP A 1 248 ? 104.024 109.396 129.960 1.00 62.52  ?  248 TRP A CB  1 
ATOM   979  C CG  . TRP A 1 248 ? 103.111 108.354 130.529 1.00 62.52  ?  248 TRP A CG  1 
ATOM   980  C CD1 . TRP A 1 248 ? 103.105 107.880 131.809 1.00 62.52  ?  248 TRP A CD1 1 
ATOM   981  C CD2 . TRP A 1 248 ? 102.071 107.652 129.837 1.00 62.52  ?  248 TRP A CD2 1 
ATOM   982  N NE1 . TRP A 1 248 ? 102.126 106.928 131.957 1.00 62.52  ?  248 TRP A NE1 1 
ATOM   983  C CE2 . TRP A 1 248 ? 101.477 106.769 130.761 1.00 62.52  ?  248 TRP A CE2 1 
ATOM   984  C CE3 . TRP A 1 248 ? 101.585 107.684 128.527 1.00 62.52  ?  248 TRP A CE3 1 
ATOM   985  C CZ2 . TRP A 1 248 ? 100.422 105.928 130.416 1.00 62.52  ?  248 TRP A CZ2 1 
ATOM   986  C CZ3 . TRP A 1 248 ? 100.538 106.848 128.187 1.00 62.52  ?  248 TRP A CZ3 1 
ATOM   987  C CH2 . TRP A 1 248 ? 99.967  105.982 129.128 1.00 62.52  ?  248 TRP A CH2 1 
ATOM   988  N N   . LEU A 1 249 ? 106.918 110.696 129.592 1.00 61.81  ?  249 LEU A N   1 
ATOM   989  C CA  . LEU A 1 249 ? 107.808 111.726 129.073 1.00 61.81  ?  249 LEU A CA  1 
ATOM   990  C C   . LEU A 1 249 ? 109.201 111.187 128.763 1.00 61.81  ?  249 LEU A C   1 
ATOM   991  O O   . LEU A 1 249 ? 110.154 111.970 128.671 1.00 61.81  ?  249 LEU A O   1 
ATOM   992  C CB  . LEU A 1 249 ? 107.901 112.888 130.066 1.00 61.81  ?  249 LEU A CB  1 
ATOM   993  C CG  . LEU A 1 249 ? 106.726 113.871 130.086 1.00 61.81  ?  249 LEU A CG  1 
ATOM   994  C CD1 . LEU A 1 249 ? 105.404 113.160 130.331 1.00 61.81  ?  249 LEU A CD1 1 
ATOM   995  C CD2 . LEU A 1 249 ? 106.958 114.944 131.138 1.00 61.81  ?  249 LEU A CD2 1 
ATOM   996  N N   . ARG A 1 250 ? 109.337 109.869 128.598 1.00 64.59  ?  250 ARG A N   1 
ATOM   997  C CA  . ARG A 1 250 ? 110.648 109.286 128.335 1.00 64.59  ?  250 ARG A CA  1 
ATOM   998  C C   . ARG A 1 250 ? 111.232 109.782 127.019 1.00 64.59  ?  250 ARG A C   1 
ATOM   999  O O   . ARG A 1 250 ? 112.457 109.844 126.870 1.00 64.59  ?  250 ARG A O   1 
ATOM   1000 C CB  . ARG A 1 250 ? 110.544 107.760 128.328 1.00 64.59  ?  250 ARG A CB  1 
ATOM   1001 C CG  . ARG A 1 250 ? 109.633 107.204 127.244 1.00 64.59  ?  250 ARG A CG  1 
ATOM   1002 C CD  . ARG A 1 250 ? 109.527 105.690 127.330 1.00 64.59  ?  250 ARG A CD  1 
ATOM   1003 N NE  . ARG A 1 250 ? 108.674 105.139 126.280 1.00 64.59  ?  250 ARG A NE  1 
ATOM   1004 C CZ  . ARG A 1 250 ? 108.412 103.844 126.129 1.00 64.59  ?  250 ARG A CZ  1 
ATOM   1005 N NH1 . ARG A 1 250 ? 107.623 103.439 125.143 1.00 64.59  1  250 ARG A NH1 1 
ATOM   1006 N NH2 . ARG A 1 250 ? 108.936 102.953 126.960 1.00 64.59  ?  250 ARG A NH2 1 
ATOM   1007 N N   . THR A 1 251 ? 110.380 110.137 126.057 1.00 61.20  ?  251 THR A N   1 
ATOM   1008 C CA  . THR A 1 251 ? 110.818 110.582 124.741 1.00 61.20  ?  251 THR A CA  1 
ATOM   1009 C C   . THR A 1 251 ? 110.616 112.080 124.534 1.00 61.20  ?  251 THR A C   1 
ATOM   1010 O O   . THR A 1 251 ? 110.478 112.527 123.390 1.00 61.20  ?  251 THR A O   1 
ATOM   1011 C CB  . THR A 1 251 ? 110.088 109.798 123.647 1.00 61.20  ?  251 THR A CB  1 
ATOM   1012 O OG1 . THR A 1 251 ? 110.551 110.221 122.358 1.00 61.20  ?  251 THR A OG1 1 
ATOM   1013 C CG2 . THR A 1 251 ? 108.579 110.011 123.737 1.00 61.20  ?  251 THR A CG2 1 
ATOM   1014 N N   . ILE A 1 252 ? 110.597 112.862 125.611 1.00 60.26  ?  252 ILE A N   1 
ATOM   1015 C CA  . ILE A 1 252 ? 110.378 114.303 125.544 1.00 60.26  ?  252 ILE A CA  1 
ATOM   1016 C C   . ILE A 1 252 ? 111.602 114.994 126.127 1.00 60.26  ?  252 ILE A C   1 
ATOM   1017 O O   . ILE A 1 252 ? 112.003 114.706 127.262 1.00 60.26  ?  252 ILE A O   1 
ATOM   1018 C CB  . ILE A 1 252 ? 109.104 114.723 126.294 1.00 60.26  ?  252 ILE A CB  1 
ATOM   1019 C CG1 . ILE A 1 252 ? 107.907 113.878 125.842 1.00 60.26  ?  252 ILE A CG1 1 
ATOM   1020 C CG2 . ILE A 1 252 ? 108.822 116.202 126.073 1.00 60.26  ?  252 ILE A CG2 1 
ATOM   1021 C CD1 . ILE A 1 252 ? 107.590 113.986 124.362 1.00 60.26  ?  252 ILE A CD1 1 
ATOM   1022 N N   . SER A 1 253 ? 112.192 115.902 125.354 1.00 59.62  ?  253 SER A N   1 
ATOM   1023 C CA  . SER A 1 253 ? 113.348 116.649 125.829 1.00 59.62  ?  253 SER A CA  1 
ATOM   1024 C C   . SER A 1 253 ? 112.958 117.541 127.002 1.00 59.62  ?  253 SER A C   1 
ATOM   1025 O O   . SER A 1 253 ? 111.804 117.956 127.140 1.00 59.62  ?  253 SER A O   1 
ATOM   1026 C CB  . SER A 1 253 ? 113.937 117.493 124.698 1.00 59.62  ?  253 SER A CB  1 
ATOM   1027 O OG  . SER A 1 253 ? 114.352 116.678 123.616 1.00 59.62  ?  253 SER A OG  1 
ATOM   1028 N N   . VAL A 1 254 ? 113.937 117.836 127.852 1.00 57.84  ?  254 VAL A N   1 
ATOM   1029 C CA  . VAL A 1 254 ? 113.730 118.629 129.060 1.00 57.84  ?  254 VAL A CA  1 
ATOM   1030 C C   . VAL A 1 254 ? 114.783 119.731 129.059 1.00 57.84  ?  254 VAL A C   1 
ATOM   1031 O O   . VAL A 1 254 ? 115.929 119.509 129.466 1.00 57.84  ?  254 VAL A O   1 
ATOM   1032 C CB  . VAL A 1 254 ? 113.812 117.779 130.333 1.00 57.84  ?  254 VAL A CB  1 
ATOM   1033 C CG1 . VAL A 1 254 ? 113.545 118.632 131.570 1.00 57.84  ?  254 VAL A CG1 1 
ATOM   1034 C CG2 . VAL A 1 254 ? 112.828 116.621 130.262 1.00 57.84  ?  254 VAL A CG2 1 
ATOM   1035 N N   . ILE A 1 255 ? 114.399 120.923 128.600 1.00 58.86  ?  255 ILE A N   1 
ATOM   1036 C CA  . ILE A 1 255 ? 115.292 122.073 128.658 1.00 58.86  ?  255 ILE A CA  1 
ATOM   1037 C C   . ILE A 1 255 ? 115.426 122.529 130.104 1.00 58.86  ?  255 ILE A C   1 
ATOM   1038 O O   . ILE A 1 255 ? 114.512 122.344 130.920 1.00 58.86  ?  255 ILE A O   1 
ATOM   1039 C CB  . ILE A 1 255 ? 114.768 123.206 127.759 1.00 58.86  ?  255 ILE A CB  1 
ATOM   1040 C CG1 . ILE A 1 255 ? 114.641 122.720 126.311 1.00 58.86  ?  255 ILE A CG1 1 
ATOM   1041 C CG2 . ILE A 1 255 ? 115.691 124.418 127.835 1.00 58.86  ?  255 ILE A CG2 1 
ATOM   1042 C CD1 . ILE A 1 255 ? 113.925 123.694 125.393 1.00 58.86  ?  255 ILE A CD1 1 
ATOM   1043 N N   . LEU A 1 256 ? 116.568 123.132 130.433 1.00 60.40  ?  256 LEU A N   1 
ATOM   1044 C CA  . LEU A 1 256 ? 116.861 123.573 131.791 1.00 60.40  ?  256 LEU A CA  1 
ATOM   1045 C C   . LEU A 1 256 ? 117.407 124.991 131.736 1.00 60.40  ?  256 LEU A C   1 
ATOM   1046 O O   . LEU A 1 256 ? 118.352 125.265 130.989 1.00 60.40  ?  256 LEU A O   1 
ATOM   1047 C CB  . LEU A 1 256 ? 117.866 122.635 132.466 1.00 60.40  ?  256 LEU A CB  1 
ATOM   1048 C CG  . LEU A 1 256 ? 118.314 123.010 133.880 1.00 60.40  ?  256 LEU A CG  1 
ATOM   1049 C CD1 . LEU A 1 256 ? 117.149 122.949 134.852 1.00 60.40  ?  256 LEU A CD1 1 
ATOM   1050 C CD2 . LEU A 1 256 ? 119.441 122.099 134.332 1.00 60.40  ?  256 LEU A CD2 1 
ATOM   1051 N N   . PHE A 1 257 ? 116.806 125.888 132.515 1.00 62.43  ?  257 PHE A N   1 
ATOM   1052 C CA  . PHE A 1 257 ? 117.257 127.271 132.635 1.00 62.43  ?  257 PHE A CA  1 
ATOM   1053 C C   . PHE A 1 257 ? 117.617 127.524 134.093 1.00 62.43  ?  257 PHE A C   1 
ATOM   1054 O O   . PHE A 1 257 ? 116.729 127.659 134.942 1.00 62.43  ?  257 PHE A O   1 
ATOM   1055 C CB  . PHE A 1 257 ? 116.181 128.248 132.160 1.00 62.43  ?  257 PHE A CB  1 
ATOM   1056 C CG  . PHE A 1 257 ? 115.863 128.146 130.691 1.00 62.43  ?  257 PHE A CG  1 
ATOM   1057 C CD1 . PHE A 1 257 ? 116.785 127.629 129.793 1.00 62.43  ?  257 PHE A CD1 1 
ATOM   1058 C CD2 . PHE A 1 257 ? 114.638 128.574 130.208 1.00 62.43  ?  257 PHE A CD2 1 
ATOM   1059 C CE1 . PHE A 1 257 ? 116.488 127.540 128.447 1.00 62.43  ?  257 PHE A CE1 1 
ATOM   1060 C CE2 . PHE A 1 257 ? 114.336 128.486 128.862 1.00 62.43  ?  257 PHE A CE2 1 
ATOM   1061 C CZ  . PHE A 1 257 ? 115.262 127.968 127.981 1.00 62.43  ?  257 PHE A CZ  1 
ATOM   1062 N N   . LEU A 1 258 ? 118.917 127.589 134.381 1.00 64.59  ?  258 LEU A N   1 
ATOM   1063 C CA  . LEU A 1 258 ? 119.400 127.845 135.738 1.00 64.59  ?  258 LEU A CA  1 
ATOM   1064 C C   . LEU A 1 258 ? 119.231 129.333 136.030 1.00 64.59  ?  258 LEU A C   1 
ATOM   1065 O O   . LEU A 1 258 ? 120.187 130.110 136.080 1.00 64.59  ?  258 LEU A O   1 
ATOM   1066 C CB  . LEU A 1 258 ? 120.848 127.396 135.887 1.00 64.59  ?  258 LEU A CB  1 
ATOM   1067 C CG  . LEU A 1 258 ? 121.128 125.917 135.605 1.00 64.59  ?  258 LEU A CG  1 
ATOM   1068 C CD1 . LEU A 1 258 ? 122.602 125.604 135.811 1.00 64.59  ?  258 LEU A CD1 1 
ATOM   1069 C CD2 . LEU A 1 258 ? 120.263 125.024 136.479 1.00 64.59  ?  258 LEU A CD2 1 
ATOM   1070 N N   . ASN A 1 259 ? 117.976 129.729 136.224 1.00 65.78  ?  259 ASN A N   1 
ATOM   1071 C CA  . ASN A 1 259 ? 117.650 131.124 136.468 1.00 65.78  ?  259 ASN A CA  1 
ATOM   1072 C C   . ASN A 1 259 ? 118.299 131.603 137.768 1.00 65.78  ?  259 ASN A C   1 
ATOM   1073 O O   . ASN A 1 259 ? 118.810 130.816 138.571 1.00 65.78  ?  259 ASN A O   1 
ATOM   1074 C CB  . ASN A 1 259 ? 116.134 131.311 136.525 1.00 65.78  ?  259 ASN A CB  1 
ATOM   1075 C CG  . ASN A 1 259 ? 115.719 132.768 136.455 1.00 65.78  ?  259 ASN A CG  1 
ATOM   1076 O OD1 . ASN A 1 259 ? 116.488 133.625 136.020 1.00 65.78  ?  259 ASN A OD1 1 
ATOM   1077 N ND2 . ASN A 1 259 ? 114.496 133.056 136.884 1.00 65.78  ?  259 ASN A ND2 1 
ATOM   1078 N N   . LYS A 1 260 ? 118.277 132.922 137.966 1.00 68.17  ?  260 LYS A N   1 
ATOM   1079 C CA  . LYS A 1 260 ? 118.818 133.547 139.174 1.00 68.17  ?  260 LYS A CA  1 
ATOM   1080 C C   . LYS A 1 260 ? 120.331 133.338 139.264 1.00 68.17  ?  260 LYS A C   1 
ATOM   1081 O O   . LYS A 1 260 ? 120.855 132.864 140.272 1.00 68.17  ?  260 LYS A O   1 
ATOM   1082 C CB  . LYS A 1 260 ? 118.116 133.015 140.427 1.00 68.17  ?  260 LYS A CB  1 
ATOM   1083 C CG  . LYS A 1 260 ? 116.598 133.098 140.366 1.00 68.17  ?  260 LYS A CG  1 
ATOM   1084 C CD  . LYS A 1 260 ? 115.958 132.532 141.623 1.00 68.17  ?  260 LYS A CD  1 
ATOM   1085 C CE  . LYS A 1 260 ? 114.441 132.518 141.518 1.00 68.17  ?  260 LYS A CE  1 
ATOM   1086 N NZ  . LYS A 1 260 ? 113.878 133.880 141.304 1.00 68.17  1  260 LYS A NZ  1 
ATOM   1087 N N   . GLN A 1 261 ? 121.034 133.702 138.189 1.00 68.71  ?  261 GLN A N   1 
ATOM   1088 C CA  . GLN A 1 261 ? 122.486 133.566 138.168 1.00 68.71  ?  261 GLN A CA  1 
ATOM   1089 C C   . GLN A 1 261 ? 123.174 134.656 138.979 1.00 68.71  ?  261 GLN A C   1 
ATOM   1090 O O   . GLN A 1 261 ? 124.206 134.395 139.606 1.00 68.71  ?  261 GLN A O   1 
ATOM   1091 C CB  . GLN A 1 261 ? 122.996 133.593 136.726 1.00 68.71  ?  261 GLN A CB  1 
ATOM   1092 C CG  . GLN A 1 261 ? 122.600 132.376 135.907 1.00 68.71  ?  261 GLN A CG  1 
ATOM   1093 C CD  . GLN A 1 261 ? 123.238 131.099 136.416 1.00 68.71  ?  261 GLN A CD  1 
ATOM   1094 O OE1 . GLN A 1 261 ? 124.126 131.132 137.268 1.00 68.71  ?  261 GLN A OE1 1 
ATOM   1095 N NE2 . GLN A 1 261 ? 122.786 129.964 135.897 1.00 68.71  ?  261 GLN A NE2 1 
ATOM   1096 N N   . ASP A 1 262 ? 122.627 135.874 138.980 1.00 69.34  ?  262 ASP A N   1 
ATOM   1097 C CA  . ASP A 1 262 ? 123.234 136.950 139.755 1.00 69.34  ?  262 ASP A CA  1 
ATOM   1098 C C   . ASP A 1 262 ? 123.188 136.647 141.247 1.00 69.34  ?  262 ASP A C   1 
ATOM   1099 O O   . ASP A 1 262 ? 124.161 136.898 141.969 1.00 69.34  ?  262 ASP A O   1 
ATOM   1100 C CB  . ASP A 1 262 ? 122.533 138.275 139.453 1.00 69.34  ?  262 ASP A CB  1 
ATOM   1101 C CG  . ASP A 1 262 ? 121.041 138.220 139.722 1.00 69.34  ?  262 ASP A CG  1 
ATOM   1102 O OD1 . ASP A 1 262 ? 120.541 137.138 140.093 1.00 69.34  ?  262 ASP A OD1 1 
ATOM   1103 O OD2 . ASP A 1 262 ? 120.369 139.260 139.561 1.00 69.34  ?  262 ASP A OD2 1 
ATOM   1104 N N   . LEU A 1 263 ? 122.066 136.106 141.729 1.00 68.77  ?  263 LEU A N   1 
ATOM   1105 C CA  . LEU A 1 263 ? 121.969 135.749 143.140 1.00 68.77  ?  263 LEU A CA  1 
ATOM   1106 C C   . LEU A 1 263 ? 122.971 134.660 143.498 1.00 68.77  ?  263 LEU A C   1 
ATOM   1107 O O   . LEU A 1 263 ? 123.630 134.732 144.542 1.00 68.77  ?  263 LEU A O   1 
ATOM   1108 C CB  . LEU A 1 263 ? 120.546 135.298 143.470 1.00 68.77  ?  263 LEU A CB  1 
ATOM   1109 C CG  . LEU A 1 263 ? 119.441 136.332 143.237 1.00 68.77  ?  263 LEU A CG  1 
ATOM   1110 C CD1 . LEU A 1 263 ? 118.077 135.732 143.540 1.00 68.77  ?  263 LEU A CD1 1 
ATOM   1111 C CD2 . LEU A 1 263 ? 119.676 137.579 144.077 1.00 68.77  ?  263 LEU A CD2 1 
ATOM   1112 N N   . LEU A 1 264 ? 123.099 133.641 142.645 1.00 68.92  ?  264 LEU A N   1 
ATOM   1113 C CA  . LEU A 1 264 ? 124.074 132.585 142.897 1.00 68.92  ?  264 LEU A CA  1 
ATOM   1114 C C   . LEU A 1 264 ? 125.491 133.142 142.926 1.00 68.92  ?  264 LEU A C   1 
ATOM   1115 O O   . LEU A 1 264 ? 126.300 132.761 143.781 1.00 68.92  ?  264 LEU A O   1 
ATOM   1116 C CB  . LEU A 1 264 ? 123.948 131.495 141.831 1.00 68.92  ?  264 LEU A CB  1 
ATOM   1117 C CG  . LEU A 1 264 ? 125.027 130.408 141.836 1.00 68.92  ?  264 LEU A CG  1 
ATOM   1118 C CD1 . LEU A 1 264 ? 125.113 129.729 143.194 1.00 68.92  ?  264 LEU A CD1 1 
ATOM   1119 C CD2 . LEU A 1 264 ? 124.755 129.387 140.742 1.00 68.92  ?  264 LEU A CD2 1 
ATOM   1120 N N   . ALA A 1 265 ? 125.813 134.041 141.994 1.00 69.97  ?  265 ALA A N   1 
ATOM   1121 C CA  . ALA A 1 265 ? 127.145 134.634 141.964 1.00 69.97  ?  265 ALA A CA  1 
ATOM   1122 C C   . ALA A 1 265 ? 127.415 135.429 143.235 1.00 69.97  ?  265 ALA A C   1 
ATOM   1123 O O   . ALA A 1 265 ? 128.474 135.289 143.857 1.00 69.97  ?  265 ALA A O   1 
ATOM   1124 C CB  . ALA A 1 265 ? 127.294 135.523 140.729 1.00 69.97  ?  265 ALA A CB  1 
ATOM   1125 N N   . GLU A 1 266 ? 126.463 136.274 143.637 1.00 68.85  ?  266 GLU A N   1 
ATOM   1126 C CA  . GLU A 1 266 ? 126.640 137.054 144.857 1.00 68.85  ?  266 GLU A CA  1 
ATOM   1127 C C   . GLU A 1 266 ? 126.799 136.147 146.071 1.00 68.85  ?  266 GLU A C   1 
ATOM   1128 O O   . GLU A 1 266 ? 127.622 136.417 146.954 1.00 68.85  ?  266 GLU A O   1 
ATOM   1129 C CB  . GLU A 1 266 ? 125.458 138.004 145.048 1.00 68.85  ?  266 GLU A CB  1 
ATOM   1130 C CG  . GLU A 1 266 ? 125.371 139.102 143.999 1.00 68.85  ?  266 GLU A CG  1 
ATOM   1131 C CD  . GLU A 1 266 ? 124.156 139.990 144.184 1.00 68.85  ?  266 GLU A CD  1 
ATOM   1132 O OE1 . GLU A 1 266 ? 123.380 139.749 145.133 1.00 68.85  ?  266 GLU A OE1 1 
ATOM   1133 O OE2 . GLU A 1 266 ? 123.976 140.928 143.380 1.00 68.85  ?  266 GLU A OE2 1 
ATOM   1134 N N   . LYS A 1 267 ? 126.027 135.060 146.128 1.00 69.62  ?  267 LYS A N   1 
ATOM   1135 C CA  . LYS A 1 267 ? 126.101 134.160 147.273 1.00 69.62  ?  267 LYS A CA  1 
ATOM   1136 C C   . LYS A 1 267 ? 127.453 133.460 147.333 1.00 69.62  ?  267 LYS A C   1 
ATOM   1137 O O   . LYS A 1 267 ? 128.087 133.404 148.393 1.00 69.62  ?  267 LYS A O   1 
ATOM   1138 C CB  . LYS A 1 267 ? 124.965 133.137 147.204 1.00 69.62  ?  267 LYS A CB  1 
ATOM   1139 C CG  . LYS A 1 267 ? 124.856 132.244 148.432 1.00 69.62  ?  267 LYS A CG  1 
ATOM   1140 C CD  . LYS A 1 267 ? 123.772 131.184 148.273 1.00 69.62  ?  267 LYS A CD  1 
ATOM   1141 C CE  . LYS A 1 267 ? 122.386 131.797 148.113 1.00 69.62  ?  267 LYS A CE  1 
ATOM   1142 N NZ  . LYS A 1 267 ? 122.037 132.714 149.233 1.00 69.62  1  267 LYS A NZ  1 
ATOM   1143 N N   . VAL A 1 268 ? 127.913 132.918 146.202 1.00 70.09  ?  268 VAL A N   1 
ATOM   1144 C CA  . VAL A 1 268 ? 129.190 132.214 146.195 1.00 70.09  ?  268 VAL A CA  1 
ATOM   1145 C C   . VAL A 1 268 ? 130.359 133.171 146.380 1.00 70.09  ?  268 VAL A C   1 
ATOM   1146 O O   . VAL A 1 268 ? 131.433 132.749 146.824 1.00 70.09  ?  268 VAL A O   1 
ATOM   1147 C CB  . VAL A 1 268 ? 129.353 131.399 144.897 1.00 70.09  ?  268 VAL A CB  1 
ATOM   1148 C CG1 . VAL A 1 268 ? 129.453 132.318 143.692 1.00 70.09  ?  268 VAL A CG1 1 
ATOM   1149 C CG2 . VAL A 1 268 ? 130.573 130.493 144.986 1.00 70.09  ?  268 VAL A CG2 1 
ATOM   1150 N N   . LEU A 1 269 ? 130.185 134.455 146.053 1.00 70.07  ?  269 LEU A N   1 
ATOM   1151 C CA  . LEU A 1 269 ? 131.246 135.425 146.298 1.00 70.07  ?  269 LEU A CA  1 
ATOM   1152 C C   . LEU A 1 269 ? 131.278 135.859 147.758 1.00 70.07  ?  269 LEU A C   1 
ATOM   1153 O O   . LEU A 1 269 ? 132.358 136.082 148.318 1.00 70.07  ?  269 LEU A O   1 
ATOM   1154 C CB  . LEU A 1 269 ? 131.067 136.640 145.387 1.00 70.07  ?  269 LEU A CB  1 
ATOM   1155 C CG  . LEU A 1 269 ? 131.352 136.418 143.900 1.00 70.07  ?  269 LEU A CG  1 
ATOM   1156 C CD1 . LEU A 1 269 ? 130.950 137.641 143.091 1.00 70.07  ?  269 LEU A CD1 1 
ATOM   1157 C CD2 . LEU A 1 269 ? 132.819 136.087 143.674 1.00 70.07  ?  269 LEU A CD2 1 
ATOM   1158 N N   . ALA A 1 270 ? 130.109 135.986 148.390 1.00 70.28  ?  270 ALA A N   1 
ATOM   1159 C CA  . ALA A 1 270 ? 130.072 136.372 149.796 1.00 70.28  ?  270 ALA A CA  1 
ATOM   1160 C C   . ALA A 1 270 ? 130.739 135.328 150.681 1.00 70.28  ?  270 ALA A C   1 
ATOM   1161 O O   . ALA A 1 270 ? 131.244 135.660 151.760 1.00 70.28  ?  270 ALA A O   1 
ATOM   1162 C CB  . ALA A 1 270 ? 128.627 136.598 150.240 1.00 70.28  ?  270 ALA A CB  1 
ATOM   1163 N N   . GLY A 1 271 ? 130.752 134.069 150.248 1.00 70.91  ?  271 GLY A N   1 
ATOM   1164 C CA  . GLY A 1 271 ? 131.375 133.007 151.008 1.00 70.91  ?  271 GLY A CA  1 
ATOM   1165 C C   . GLY A 1 271 ? 130.622 132.568 152.243 1.00 70.91  ?  271 GLY A C   1 
ATOM   1166 O O   . GLY A 1 271 ? 131.093 131.663 152.942 1.00 70.91  ?  271 GLY A O   1 
ATOM   1167 N N   . LYS A 1 272 ? 129.470 133.173 152.540 1.00 72.86  ?  272 LYS A N   1 
ATOM   1168 C CA  . LYS A 1 272 ? 128.714 132.789 153.726 1.00 72.86  ?  272 LYS A CA  1 
ATOM   1169 C C   . LYS A 1 272 ? 127.980 131.468 153.532 1.00 72.86  ?  272 LYS A C   1 
ATOM   1170 O O   . LYS A 1 272 ? 127.700 130.771 154.514 1.00 72.86  ?  272 LYS A O   1 
ATOM   1171 C CB  . LYS A 1 272 ? 127.716 133.890 154.091 1.00 72.86  ?  272 LYS A CB  1 
ATOM   1172 C CG  . LYS A 1 272 ? 128.325 135.285 154.190 1.00 72.86  ?  272 LYS A CG  1 
ATOM   1173 C CD  . LYS A 1 272 ? 129.510 135.342 155.149 1.00 72.86  ?  272 LYS A CD  1 
ATOM   1174 C CE  . LYS A 1 272 ? 129.117 134.959 156.568 1.00 72.86  ?  272 LYS A CE  1 
ATOM   1175 N NZ  . LYS A 1 272 ? 130.255 135.105 157.517 1.00 72.86  1  272 LYS A NZ  1 
ATOM   1176 N N   . SER A 1 273 ? 127.663 131.110 152.289 1.00 72.39  ?  273 SER A N   1 
ATOM   1177 C CA  . SER A 1 273 ? 126.972 129.866 151.971 1.00 72.39  ?  273 SER A CA  1 
ATOM   1178 C C   . SER A 1 273 ? 127.800 129.097 150.952 1.00 72.39  ?  273 SER A C   1 
ATOM   1179 O O   . SER A 1 273 ? 127.976 129.556 149.818 1.00 72.39  ?  273 SER A O   1 
ATOM   1180 C CB  . SER A 1 273 ? 125.568 130.140 151.427 1.00 72.39  ?  273 SER A CB  1 
ATOM   1181 O OG  . SER A 1 273 ? 124.783 130.843 152.375 1.00 72.39  ?  273 SER A OG  1 
ATOM   1182 N N   . LYS A 1 274 ? 128.304 127.935 151.356 1.00 72.52  ?  274 LYS A N   1 
ATOM   1183 C CA  . LYS A 1 274 ? 129.135 127.093 150.508 1.00 72.52  ?  274 LYS A CA  1 
ATOM   1184 C C   . LYS A 1 274 ? 128.366 125.844 150.102 1.00 72.52  ?  274 LYS A C   1 
ATOM   1185 O O   . LYS A 1 274 ? 127.674 125.234 150.924 1.00 72.52  ?  274 LYS A O   1 
ATOM   1186 C CB  . LYS A 1 274 ? 130.427 126.697 151.229 1.00 72.52  ?  274 LYS A CB  1 
ATOM   1187 C CG  . LYS A 1 274 ? 131.305 127.877 151.620 1.00 72.52  ?  274 LYS A CG  1 
ATOM   1188 C CD  . LYS A 1 274 ? 132.497 127.442 152.462 1.00 72.52  ?  274 LYS A CD  1 
ATOM   1189 C CE  . LYS A 1 274 ? 133.451 126.550 151.679 1.00 72.52  ?  274 LYS A CE  1 
ATOM   1190 N NZ  . LYS A 1 274 ? 134.655 126.188 152.476 1.00 72.52  1  274 LYS A NZ  1 
ATOM   1191 N N   . ILE A 1 275 ? 128.491 125.467 148.827 1.00 70.96  ?  275 ILE A N   1 
ATOM   1192 C CA  . ILE A 1 275 ? 127.824 124.268 148.337 1.00 70.96  ?  275 ILE A CA  1 
ATOM   1193 C C   . ILE A 1 275 ? 128.381 123.013 148.996 1.00 70.96  ?  275 ILE A C   1 
ATOM   1194 O O   . ILE A 1 275 ? 127.696 121.984 149.040 1.00 70.96  ?  275 ILE A O   1 
ATOM   1195 C CB  . ILE A 1 275 ? 127.947 124.175 146.804 1.00 70.96  ?  275 ILE A CB  1 
ATOM   1196 C CG1 . ILE A 1 275 ? 127.312 125.405 146.146 1.00 70.96  ?  275 ILE A CG1 1 
ATOM   1197 C CG2 . ILE A 1 275 ? 127.294 122.893 146.293 1.00 70.96  ?  275 ILE A CG2 1 
ATOM   1198 C CD1 . ILE A 1 275 ? 127.535 125.492 144.649 1.00 70.96  ?  275 ILE A CD1 1 
ATOM   1199 N N   . GLU A 1 276 ? 129.611 123.070 149.513 1.00 72.64  ?  276 GLU A N   1 
ATOM   1200 C CA  . GLU A 1 276 ? 130.197 121.901 150.160 1.00 72.64  ?  276 GLU A CA  1 
ATOM   1201 C C   . GLU A 1 276 ? 129.372 121.454 151.359 1.00 72.64  ?  276 GLU A C   1 
ATOM   1202 O O   . GLU A 1 276 ? 129.343 120.260 151.682 1.00 72.64  ?  276 GLU A O   1 
ATOM   1203 C CB  . GLU A 1 276 ? 131.635 122.208 150.583 1.00 72.64  ?  276 GLU A CB  1 
ATOM   1204 C CG  . GLU A 1 276 ? 132.395 121.023 151.172 1.00 72.64  ?  276 GLU A CG  1 
ATOM   1205 C CD  . GLU A 1 276 ? 132.104 120.797 152.646 1.00 72.64  ?  276 GLU A CD  1 
ATOM   1206 O OE1 . GLU A 1 276 ? 131.527 121.699 153.290 1.00 72.64  ?  276 GLU A OE1 1 
ATOM   1207 O OE2 . GLU A 1 276 ? 132.455 119.715 153.161 1.00 72.64  ?  276 GLU A OE2 1 
ATOM   1208 N N   . ASP A 1 277 ? 128.698 122.390 152.031 1.00 71.92  ?  277 ASP A N   1 
ATOM   1209 C CA  . ASP A 1 277 ? 127.904 122.031 153.202 1.00 71.92  ?  277 ASP A CA  1 
ATOM   1210 C C   . ASP A 1 277 ? 126.795 121.048 152.850 1.00 71.92  ?  277 ASP A C   1 
ATOM   1211 O O   . ASP A 1 277 ? 126.406 120.227 153.688 1.00 71.92  ?  277 ASP A O   1 
ATOM   1212 C CB  . ASP A 1 277 ? 127.313 123.289 153.839 1.00 71.92  ?  277 ASP A CB  1 
ATOM   1213 C CG  . ASP A 1 277 ? 128.378 124.271 154.285 1.00 71.92  ?  277 ASP A CG  1 
ATOM   1214 O OD1 . ASP A 1 277 ? 129.490 123.825 154.640 1.00 71.92  ?  277 ASP A OD1 1 
ATOM   1215 O OD2 . ASP A 1 277 ? 128.104 125.490 154.282 1.00 71.92  ?  277 ASP A OD2 1 
ATOM   1216 N N   . TYR A 1 278 ? 126.276 121.113 151.624 1.00 70.48  ?  278 TYR A N   1 
ATOM   1217 C CA  . TYR A 1 278 ? 125.193 120.243 151.183 1.00 70.48  ?  278 TYR A CA  1 
ATOM   1218 C C   . TYR A 1 278 ? 125.671 119.101 150.296 1.00 70.48  ?  278 TYR A C   1 
ATOM   1219 O O   . TYR A 1 278 ? 125.140 117.991 150.388 1.00 70.48  ?  278 TYR A O   1 
ATOM   1220 C CB  . TYR A 1 278 ? 124.138 121.058 150.429 1.00 70.48  ?  278 TYR A CB  1 
ATOM   1221 C CG  . TYR A 1 278 ? 123.491 122.140 151.265 1.00 70.48  ?  278 TYR A CG  1 
ATOM   1222 C CD1 . TYR A 1 278 ? 122.348 121.879 152.009 1.00 70.48  ?  278 TYR A CD1 1 
ATOM   1223 C CD2 . TYR A 1 278 ? 124.023 123.422 151.309 1.00 70.48  ?  278 TYR A CD2 1 
ATOM   1224 C CE1 . TYR A 1 278 ? 121.753 122.863 152.774 1.00 70.48  ?  278 TYR A CE1 1 
ATOM   1225 C CE2 . TYR A 1 278 ? 123.434 124.413 152.072 1.00 70.48  ?  278 TYR A CE2 1 
ATOM   1226 C CZ  . TYR A 1 278 ? 122.300 124.129 152.802 1.00 70.48  ?  278 TYR A CZ  1 
ATOM   1227 O OH  . TYR A 1 278 ? 121.711 125.112 153.562 1.00 70.48  ?  278 TYR A OH  1 
ATOM   1228 N N   . PHE A 1 279 ? 126.657 119.347 149.442 1.00 69.66  ?  279 PHE A N   1 
ATOM   1229 C CA  . PHE A 1 279 ? 127.174 118.332 148.523 1.00 69.66  ?  279 PHE A CA  1 
ATOM   1230 C C   . PHE A 1 279 ? 128.648 118.082 148.807 1.00 69.66  ?  279 PHE A C   1 
ATOM   1231 O O   . PHE A 1 279 ? 129.481 118.975 148.558 1.00 69.66  ?  279 PHE A O   1 
ATOM   1232 C CB  . PHE A 1 279 ? 126.979 118.773 147.073 1.00 69.66  ?  279 PHE A CB  1 
ATOM   1233 C CG  . PHE A 1 279 ? 125.541 118.817 146.643 1.00 69.66  ?  279 PHE A CG  1 
ATOM   1234 C CD1 . PHE A 1 279 ? 124.761 119.931 146.901 1.00 69.66  ?  279 PHE A CD1 1 
ATOM   1235 C CD2 . PHE A 1 279 ? 124.969 117.743 145.982 1.00 69.66  ?  279 PHE A CD2 1 
ATOM   1236 C CE1 . PHE A 1 279 ? 123.437 119.973 146.508 1.00 69.66  ?  279 PHE A CE1 1 
ATOM   1237 C CE2 . PHE A 1 279 ? 123.646 117.779 145.586 1.00 69.66  ?  279 PHE A CE2 1 
ATOM   1238 C CZ  . PHE A 1 279 ? 122.879 118.896 145.849 1.00 69.66  ?  279 PHE A CZ  1 
ATOM   1239 N N   . PRO A 1 280 ? 129.032 116.908 149.319 1.00 70.90  ?  280 PRO A N   1 
ATOM   1240 C CA  . PRO A 1 280 ? 130.462 116.668 149.568 1.00 70.90  ?  280 PRO A CA  1 
ATOM   1241 C C   . PRO A 1 280 ? 131.285 116.589 148.296 1.00 70.90  ?  280 PRO A C   1 
ATOM   1242 O O   . PRO A 1 280 ? 132.470 116.946 148.316 1.00 70.90  ?  280 PRO A O   1 
ATOM   1243 C CB  . PRO A 1 280 ? 130.468 115.337 150.332 1.00 70.90  ?  280 PRO A CB  1 
ATOM   1244 C CG  . PRO A 1 280 ? 129.219 114.654 149.904 1.00 70.90  ?  280 PRO A CG  1 
ATOM   1245 C CD  . PRO A 1 280 ? 128.207 115.741 149.681 1.00 70.90  ?  280 PRO A CD  1 
ATOM   1246 N N   . GLU A 1 281 ? 130.696 116.133 147.187 1.00 71.66  ?  281 GLU A N   1 
ATOM   1247 C CA  . GLU A 1 281 ? 131.439 116.056 145.934 1.00 71.66  ?  281 GLU A CA  1 
ATOM   1248 C C   . GLU A 1 281 ? 131.973 117.419 145.516 1.00 71.66  ?  281 GLU A C   1 
ATOM   1249 O O   . GLU A 1 281 ? 132.985 117.498 144.810 1.00 71.66  ?  281 GLU A O   1 
ATOM   1250 C CB  . GLU A 1 281 ? 130.550 115.476 144.833 1.00 71.66  ?  281 GLU A CB  1 
ATOM   1251 C CG  . GLU A 1 281 ? 130.053 114.068 145.116 1.00 71.66  ?  281 GLU A CG  1 
ATOM   1252 C CD  . GLU A 1 281 ? 129.186 113.521 143.998 1.00 71.66  ?  281 GLU A CD  1 
ATOM   1253 O OE1 . GLU A 1 281 ? 128.975 114.242 143.001 1.00 71.66  ?  281 GLU A OE1 1 
ATOM   1254 O OE2 . GLU A 1 281 ? 128.717 112.369 144.117 1.00 71.66  ?  281 GLU A OE2 1 
ATOM   1255 N N   . PHE A 1 282 ? 131.311 118.499 145.937 1.00 71.75  ?  282 PHE A N   1 
ATOM   1256 C CA  . PHE A 1 282 ? 131.785 119.837 145.608 1.00 71.75  ?  282 PHE A CA  1 
ATOM   1257 C C   . PHE A 1 282 ? 133.178 120.104 146.160 1.00 71.75  ?  282 PHE A C   1 
ATOM   1258 O O   . PHE A 1 282 ? 133.890 120.962 145.627 1.00 71.75  ?  282 PHE A O   1 
ATOM   1259 C CB  . PHE A 1 282 ? 130.803 120.882 146.143 1.00 71.75  ?  282 PHE A CB  1 
ATOM   1260 C CG  . PHE A 1 282 ? 131.167 122.296 145.790 1.00 71.75  ?  282 PHE A CG  1 
ATOM   1261 C CD1 . PHE A 1 282 ? 130.799 122.835 144.568 1.00 71.75  ?  282 PHE A CD1 1 
ATOM   1262 C CD2 . PHE A 1 282 ? 131.872 123.088 146.681 1.00 71.75  ?  282 PHE A CD2 1 
ATOM   1263 C CE1 . PHE A 1 282 ? 131.130 124.136 144.241 1.00 71.75  ?  282 PHE A CE1 1 
ATOM   1264 C CE2 . PHE A 1 282 ? 132.205 124.390 146.359 1.00 71.75  ?  282 PHE A CE2 1 
ATOM   1265 C CZ  . PHE A 1 282 ? 131.834 124.914 145.137 1.00 71.75  ?  282 PHE A CZ  1 
ATOM   1266 N N   . ALA A 1 283 ? 133.585 119.389 147.211 1.00 73.31  ?  283 ALA A N   1 
ATOM   1267 C CA  . ALA A 1 283 ? 134.916 119.580 147.773 1.00 73.31  ?  283 ALA A CA  1 
ATOM   1268 C C   . ALA A 1 283 ? 135.988 118.870 146.957 1.00 73.31  ?  283 ALA A C   1 
ATOM   1269 O O   . ALA A 1 283 ? 137.147 119.301 146.958 1.00 73.31  ?  283 ALA A O   1 
ATOM   1270 C CB  . ALA A 1 283 ? 134.952 119.086 149.220 1.00 73.31  ?  283 ALA A CB  1 
ATOM   1271 N N   . ARG A 1 284 ? 135.627 117.791 146.262 1.00 72.35  ?  284 ARG A N   1 
ATOM   1272 C CA  . ARG A 1 284 ? 136.561 117.019 145.452 1.00 72.35  ?  284 ARG A CA  1 
ATOM   1273 C C   . ARG A 1 284 ? 136.251 117.138 143.962 1.00 72.35  ?  284 ARG A C   1 
ATOM   1274 O O   . ARG A 1 284 ? 136.560 116.233 143.184 1.00 72.35  ?  284 ARG A O   1 
ATOM   1275 C CB  . ARG A 1 284 ? 136.547 115.552 145.881 1.00 72.35  ?  284 ARG A CB  1 
ATOM   1276 C CG  . ARG A 1 284 ? 135.188 114.880 145.745 1.00 72.35  ?  284 ARG A CG  1 
ATOM   1277 C CD  . ARG A 1 284 ? 135.243 113.419 146.161 1.00 72.35  ?  284 ARG A CD  1 
ATOM   1278 N NE  . ARG A 1 284 ? 135.619 113.259 147.563 1.00 72.35  ?  284 ARG A NE  1 
ATOM   1279 C CZ  . ARG A 1 284 ? 135.731 112.087 148.180 1.00 72.35  ?  284 ARG A CZ  1 
ATOM   1280 N NH1 . ARG A 1 284 ? 135.496 110.958 147.522 1.00 72.35  1  284 ARG A NH1 1 
ATOM   1281 N NH2 . ARG A 1 284 ? 136.078 112.041 149.459 1.00 72.35  ?  284 ARG A NH2 1 
ATOM   1282 N N   . TYR A 1 285 ? 135.643 118.248 143.554 1.00 72.54  ?  285 TYR A N   1 
ATOM   1283 C CA  . TYR A 1 285 ? 135.276 118.483 142.163 1.00 72.54  ?  285 TYR A CA  1 
ATOM   1284 C C   . TYR A 1 285 ? 136.250 119.483 141.553 1.00 72.54  ?  285 TYR A C   1 
ATOM   1285 O O   . TYR A 1 285 ? 136.416 120.591 142.074 1.00 72.54  ?  285 TYR A O   1 
ATOM   1286 C CB  . TYR A 1 285 ? 133.841 118.997 142.059 1.00 72.54  ?  285 TYR A CB  1 
ATOM   1287 C CG  . TYR A 1 285 ? 133.407 119.316 140.646 1.00 72.54  ?  285 TYR A CG  1 
ATOM   1288 C CD1 . TYR A 1 285 ? 132.897 118.328 139.816 1.00 72.54  ?  285 TYR A CD1 1 
ATOM   1289 C CD2 . TYR A 1 285 ? 133.504 120.607 140.143 1.00 72.54  ?  285 TYR A CD2 1 
ATOM   1290 C CE1 . TYR A 1 285 ? 132.498 118.615 138.524 1.00 72.54  ?  285 TYR A CE1 1 
ATOM   1291 C CE2 . TYR A 1 285 ? 133.108 120.904 138.853 1.00 72.54  ?  285 TYR A CE2 1 
ATOM   1292 C CZ  . TYR A 1 285 ? 132.606 119.904 138.048 1.00 72.54  ?  285 TYR A CZ  1 
ATOM   1293 O OH  . TYR A 1 285 ? 132.210 120.195 136.763 1.00 72.54  ?  285 TYR A OH  1 
ATOM   1294 N N   . THR A 1 286 ? 136.887 119.091 140.455 1.00 73.35  ?  286 THR A N   1 
ATOM   1295 C CA  . THR A 1 286 ? 137.822 119.955 139.752 1.00 73.35  ?  286 THR A CA  1 
ATOM   1296 C C   . THR A 1 286 ? 137.109 120.707 138.635 1.00 73.35  ?  286 THR A C   1 
ATOM   1297 O O   . THR A 1 286 ? 136.162 120.203 138.024 1.00 73.35  ?  286 THR A O   1 
ATOM   1298 C CB  . THR A 1 286 ? 138.986 119.146 139.172 1.00 73.35  ?  286 THR A CB  1 
ATOM   1299 O OG1 . THR A 1 286 ? 139.954 120.035 138.601 1.00 73.35  ?  286 THR A OG1 1 
ATOM   1300 C CG2 . THR A 1 286 ? 138.497 118.177 138.098 1.00 73.35  ?  286 THR A CG2 1 
ATOM   1301 N N   . THR A 1 287 ? 137.572 121.924 138.376 1.00 74.55  ?  287 THR A N   1 
ATOM   1302 C CA  . THR A 1 287 ? 136.971 122.738 137.331 1.00 74.55  ?  287 THR A CA  1 
ATOM   1303 C C   . THR A 1 287 ? 137.153 122.052 135.979 1.00 74.55  ?  287 THR A C   1 
ATOM   1304 O O   . THR A 1 287 ? 138.251 121.560 135.684 1.00 74.55  ?  287 THR A O   1 
ATOM   1305 C CB  . THR A 1 287 ? 137.604 124.129 137.304 1.00 74.55  ?  287 THR A CB  1 
ATOM   1306 O OG1 . THR A 1 287 ? 137.480 124.740 138.595 1.00 74.55  ?  287 THR A OG1 1 
ATOM   1307 C CG2 . THR A 1 287 ? 136.924 125.010 136.263 1.00 74.55  ?  287 THR A CG2 1 
ATOM   1308 N N   . PRO A 1 288 ? 136.118 121.990 135.138 1.00 77.59  ?  288 PRO A N   1 
ATOM   1309 C CA  . PRO A 1 288 ? 136.284 121.356 133.825 1.00 77.59  ?  288 PRO A CA  1 
ATOM   1310 C C   . PRO A 1 288 ? 137.395 122.017 133.023 1.00 77.59  ?  288 PRO A C   1 
ATOM   1311 O O   . PRO A 1 288 ? 137.545 123.241 133.022 1.00 77.59  ?  288 PRO A O   1 
ATOM   1312 C CB  . PRO A 1 288 ? 134.916 121.549 133.160 1.00 77.59  ?  288 PRO A CB  1 
ATOM   1313 C CG  . PRO A 1 288 ? 133.965 121.719 134.288 1.00 77.59  ?  288 PRO A CG  1 
ATOM   1314 C CD  . PRO A 1 288 ? 134.729 122.429 135.363 1.00 77.59  ?  288 PRO A CD  1 
ATOM   1315 N N   . GLU A 1 289 ? 138.181 121.187 132.333 1.00 82.26  ?  289 GLU A N   1 
ATOM   1316 C CA  . GLU A 1 289 ? 139.277 121.712 131.525 1.00 82.26  ?  289 GLU A CA  1 
ATOM   1317 C C   . GLU A 1 289 ? 138.759 122.354 130.244 1.00 82.26  ?  289 GLU A C   1 
ATOM   1318 O O   . GLU A 1 289 ? 139.319 123.350 129.773 1.00 82.26  ?  289 GLU A O   1 
ATOM   1319 C CB  . GLU A 1 289 ? 140.272 120.597 131.200 1.00 82.26  ?  289 GLU A CB  1 
ATOM   1320 C CG  . GLU A 1 289 ? 141.105 120.129 132.388 1.00 82.26  ?  289 GLU A CG  1 
ATOM   1321 C CD  . GLU A 1 289 ? 140.286 119.397 133.433 1.00 82.26  ?  289 GLU A CD  1 
ATOM   1322 O OE1 . GLU A 1 289 ? 139.068 119.218 133.219 1.00 82.26  ?  289 GLU A OE1 1 
ATOM   1323 O OE2 . GLU A 1 289 ? 140.859 119.000 134.469 1.00 82.26  ?  289 GLU A OE2 1 
ATOM   1324 N N   . ASP A 1 290 ? 137.693 121.799 129.668 1.00 83.38  ?  290 ASP A N   1 
ATOM   1325 C CA  . ASP A 1 290 ? 137.088 122.331 128.456 1.00 83.38  ?  290 ASP A CA  1 
ATOM   1326 C C   . ASP A 1 290 ? 136.048 123.408 128.744 1.00 83.38  ?  290 ASP A C   1 
ATOM   1327 O O   . ASP A 1 290 ? 135.204 123.689 127.884 1.00 83.38  ?  290 ASP A O   1 
ATOM   1328 C CB  . ASP A 1 290 ? 136.455 121.197 127.646 1.00 83.38  ?  290 ASP A CB  1 
ATOM   1329 C CG  . ASP A 1 290 ? 137.462 120.138 127.241 1.00 83.38  ?  290 ASP A CG  1 
ATOM   1330 O OD1 . ASP A 1 290 ? 137.937 119.397 128.128 1.00 83.38  ?  290 ASP A OD1 1 
ATOM   1331 O OD2 . ASP A 1 290 ? 137.778 120.045 126.036 1.00 83.38  ?  290 ASP A OD2 1 
ATOM   1332 N N   . ALA A 1 291 ? 136.088 124.013 129.928 1.00 79.86  ?  291 ALA A N   1 
ATOM   1333 C CA  . ALA A 1 291 ? 135.119 125.035 130.283 1.00 79.86  ?  291 ALA A CA  1 
ATOM   1334 C C   . ALA A 1 291 ? 135.284 126.264 129.388 1.00 79.86  ?  291 ALA A C   1 
ATOM   1335 O O   . ALA A 1 291 ? 136.240 126.391 128.620 1.00 79.86  ?  291 ALA A O   1 
ATOM   1336 C CB  . ALA A 1 291 ? 135.270 125.426 131.752 1.00 79.86  ?  291 ALA A CB  1 
ATOM   1337 N N   . THR A 1 292 ? 134.324 127.180 129.502 1.00 81.78  ?  292 THR A N   1 
ATOM   1338 C CA  . THR A 1 292 ? 134.322 128.431 128.741 1.00 81.78  ?  292 THR A CA  1 
ATOM   1339 C C   . THR A 1 292 ? 133.899 129.562 129.668 1.00 81.78  ?  292 THR A C   1 
ATOM   1340 O O   . THR A 1 292 ? 132.781 130.082 129.575 1.00 81.78  ?  292 THR A O   1 
ATOM   1341 C CB  . THR A 1 292 ? 133.392 128.333 127.530 1.00 81.78  ?  292 THR A CB  1 
ATOM   1342 O OG1 . THR A 1 292 ? 132.057 128.052 127.969 1.00 81.78  ?  292 THR A OG1 1 
ATOM   1343 C CG2 . THR A 1 292 ? 133.855 127.233 126.585 1.00 81.78  ?  292 THR A CG2 1 
ATOM   1344 N N   . PRO A 1 293 ? 134.776 129.967 130.585 1.00 81.79  ?  293 PRO A N   1 
ATOM   1345 C CA  . PRO A 1 293 ? 134.416 131.041 131.520 1.00 81.79  ?  293 PRO A CA  1 
ATOM   1346 C C   . PRO A 1 293 ? 134.059 132.323 130.783 1.00 81.79  ?  293 PRO A C   1 
ATOM   1347 O O   . PRO A 1 293 ? 134.770 132.759 129.875 1.00 81.79  ?  293 PRO A O   1 
ATOM   1348 C CB  . PRO A 1 293 ? 135.680 131.210 132.372 1.00 81.79  ?  293 PRO A CB  1 
ATOM   1349 C CG  . PRO A 1 293 ? 136.421 129.924 132.228 1.00 81.79  ?  293 PRO A CG  1 
ATOM   1350 C CD  . PRO A 1 293 ? 136.122 129.432 130.848 1.00 81.79  ?  293 PRO A CD  1 
ATOM   1351 N N   . GLU A 1 294 ? 132.943 132.927 131.182 1.00 84.61  ?  294 GLU A N   1 
ATOM   1352 C CA  . GLU A 1 294 ? 132.523 134.179 130.580 1.00 84.61  ?  294 GLU A CA  1 
ATOM   1353 C C   . GLU A 1 294 ? 133.412 135.322 131.071 1.00 84.61  ?  294 GLU A C   1 
ATOM   1354 O O   . GLU A 1 294 ? 133.997 135.243 132.154 1.00 84.61  ?  294 GLU A O   1 
ATOM   1355 C CB  . GLU A 1 294 ? 131.063 134.475 130.915 1.00 84.61  ?  294 GLU A CB  1 
ATOM   1356 C CG  . GLU A 1 294 ? 130.059 133.585 130.192 1.00 84.61  ?  294 GLU A CG  1 
ATOM   1357 C CD  . GLU A 1 294 ? 130.105 132.143 130.659 1.00 84.61  ?  294 GLU A CD  1 
ATOM   1358 O OE1 . GLU A 1 294 ? 130.899 131.837 131.573 1.00 84.61  ?  294 GLU A OE1 1 
ATOM   1359 O OE2 . GLU A 1 294 ? 129.347 131.315 130.111 1.00 84.61  ?  294 GLU A OE2 1 
ATOM   1360 N N   . PRO A 1 295 ? 133.532 136.397 130.291 1.00 85.54  ?  295 PRO A N   1 
ATOM   1361 C CA  . PRO A 1 295 ? 134.397 137.511 130.706 1.00 85.54  ?  295 PRO A CA  1 
ATOM   1362 C C   . PRO A 1 295 ? 133.857 138.192 131.956 1.00 85.54  ?  295 PRO A C   1 
ATOM   1363 O O   . PRO A 1 295 ? 132.684 138.563 132.022 1.00 85.54  ?  295 PRO A O   1 
ATOM   1364 C CB  . PRO A 1 295 ? 134.377 138.449 129.494 1.00 85.54  ?  295 PRO A CB  1 
ATOM   1365 C CG  . PRO A 1 295 ? 133.105 138.128 128.787 1.00 85.54  ?  295 PRO A CG  1 
ATOM   1366 C CD  . PRO A 1 295 ? 132.877 136.660 128.998 1.00 85.54  ?  295 PRO A CD  1 
ATOM   1367 N N   . GLY A 1 296 ? 134.728 138.353 132.949 1.00 84.81  ?  296 GLY A N   1 
ATOM   1368 C CA  . GLY A 1 296 ? 134.366 139.013 134.185 1.00 84.81  ?  296 GLY A CA  1 
ATOM   1369 C C   . GLY A 1 296 ? 133.810 138.111 135.263 1.00 84.81  ?  296 GLY A C   1 
ATOM   1370 O O   . GLY A 1 296 ? 133.326 138.620 136.281 1.00 84.81  ?  296 GLY A O   1 
ATOM   1371 N N   . GLU A 1 297 ? 133.859 136.794 135.078 1.00 79.95  ?  297 GLU A N   1 
ATOM   1372 C CA  . GLU A 1 297 ? 133.344 135.856 136.064 1.00 79.95  ?  297 GLU A CA  1 
ATOM   1373 C C   . GLU A 1 297 ? 134.457 135.409 137.003 1.00 79.95  ?  297 GLU A C   1 
ATOM   1374 O O   . GLU A 1 297 ? 135.575 135.118 136.569 1.00 79.95  ?  297 GLU A O   1 
ATOM   1375 C CB  . GLU A 1 297 ? 132.722 134.639 135.379 1.00 79.95  ?  297 GLU A CB  1 
ATOM   1376 C CG  . GLU A 1 297 ? 131.489 134.955 134.546 1.00 79.95  ?  297 GLU A CG  1 
ATOM   1377 C CD  . GLU A 1 297 ? 130.330 135.460 135.384 1.00 79.95  ?  297 GLU A CD  1 
ATOM   1378 O OE1 . GLU A 1 297 ? 130.405 135.365 136.627 1.00 79.95  ?  297 GLU A OE1 1 
ATOM   1379 O OE2 . GLU A 1 297 ? 129.343 135.953 134.798 1.00 79.95  ?  297 GLU A OE2 1 
ATOM   1380 N N   . ASP A 1 298 ? 134.139 135.356 138.293 1.00 74.60  ?  298 ASP A N   1 
ATOM   1381 C CA  . ASP A 1 298 ? 135.104 134.905 139.279 1.00 74.60  ?  298 ASP A CA  1 
ATOM   1382 C C   . ASP A 1 298 ? 135.294 133.391 139.172 1.00 74.60  ?  298 ASP A C   1 
ATOM   1383 O O   . ASP A 1 298 ? 134.346 132.661 138.873 1.00 74.60  ?  298 ASP A O   1 
ATOM   1384 C CB  . ASP A 1 298 ? 134.637 135.274 140.684 1.00 74.60  ?  298 ASP A CB  1 
ATOM   1385 C CG  . ASP A 1 298 ? 135.675 134.969 141.745 1.00 74.60  ?  298 ASP A CG  1 
ATOM   1386 O OD1 . ASP A 1 298 ? 136.671 135.716 141.835 1.00 74.60  ?  298 ASP A OD1 1 
ATOM   1387 O OD2 . ASP A 1 298 ? 135.495 133.982 142.489 1.00 74.60  ?  298 ASP A OD2 1 
ATOM   1388 N N   . PRO A 1 299 ? 136.515 132.892 139.400 1.00 74.57  ?  299 PRO A N   1 
ATOM   1389 C CA  . PRO A 1 299 ? 136.725 131.436 139.322 1.00 74.57  ?  299 PRO A CA  1 
ATOM   1390 C C   . PRO A 1 299 ? 135.746 130.632 140.161 1.00 74.57  ?  299 PRO A C   1 
ATOM   1391 O O   . PRO A 1 299 ? 135.321 129.550 139.738 1.00 74.57  ?  299 PRO A O   1 
ATOM   1392 C CB  . PRO A 1 299 ? 138.169 131.272 139.812 1.00 74.57  ?  299 PRO A CB  1 
ATOM   1393 C CG  . PRO A 1 299 ? 138.827 132.553 139.461 1.00 74.57  ?  299 PRO A CG  1 
ATOM   1394 C CD  . PRO A 1 299 ? 137.779 133.614 139.639 1.00 74.57  ?  299 PRO A CD  1 
ATOM   1395 N N   . ARG A 1 300 ? 135.371 131.130 141.342 1.00 73.61  ?  300 ARG A N   1 
ATOM   1396 C CA  . ARG A 1 300 ? 134.433 130.395 142.184 1.00 73.61  ?  300 ARG A CA  1 
ATOM   1397 C C   . ARG A 1 300 ? 133.054 130.319 141.539 1.00 73.61  ?  300 ARG A C   1 
ATOM   1398 O O   . ARG A 1 300 ? 132.411 129.264 141.561 1.00 73.61  ?  300 ARG A O   1 
ATOM   1399 C CB  . ARG A 1 300 ? 134.344 131.044 143.566 1.00 73.61  ?  300 ARG A CB  1 
ATOM   1400 C CG  . ARG A 1 300 ? 135.436 130.609 144.536 1.00 73.61  ?  300 ARG A CG  1 
ATOM   1401 C CD  . ARG A 1 300 ? 136.825 131.012 144.063 1.00 73.61  ?  300 ARG A CD  1 
ATOM   1402 N NE  . ARG A 1 300 ? 136.959 132.459 143.911 1.00 73.61  ?  300 ARG A NE  1 
ATOM   1403 C CZ  . ARG A 1 300 ? 137.259 133.296 144.901 1.00 73.61  ?  300 ARG A CZ  1 
ATOM   1404 N NH1 . ARG A 1 300 ? 137.457 132.842 146.132 1.00 73.61  1  300 ARG A NH1 1 
ATOM   1405 N NH2 . ARG A 1 300 ? 137.358 134.596 144.660 1.00 73.61  ?  300 ARG A NH2 1 
ATOM   1406 N N   . VAL A 1 301 ? 132.582 131.427 140.964 1.00 72.58  ?  301 VAL A N   1 
ATOM   1407 C CA  . VAL A 1 301 ? 131.284 131.424 140.293 1.00 72.58  ?  301 VAL A CA  1 
ATOM   1408 C C   . VAL A 1 301 ? 131.293 130.428 139.140 1.00 72.58  ?  301 VAL A C   1 
ATOM   1409 O O   . VAL A 1 301 ? 130.358 129.634 138.968 1.00 72.58  ?  301 VAL A O   1 
ATOM   1410 C CB  . VAL A 1 301 ? 130.928 132.840 139.804 1.00 72.58  ?  301 VAL A CB  1 
ATOM   1411 C CG1 . VAL A 1 301 ? 129.589 132.833 139.077 1.00 72.58  ?  301 VAL A CG1 1 
ATOM   1412 C CG2 . VAL A 1 301 ? 130.897 133.825 140.966 1.00 72.58  ?  301 VAL A CG2 1 
ATOM   1413 N N   . THR A 1 302 ? 132.348 130.469 138.323 1.00 73.18  ?  302 THR A N   1 
ATOM   1414 C CA  . THR A 1 302 ? 132.456 129.551 137.195 1.00 73.18  ?  302 THR A CA  1 
ATOM   1415 C C   . THR A 1 302 ? 132.458 128.104 137.671 1.00 73.18  ?  302 THR A C   1 
ATOM   1416 O O   . THR A 1 302 ? 131.748 127.255 137.120 1.00 73.18  ?  302 THR A O   1 
ATOM   1417 C CB  . THR A 1 302 ? 133.723 129.854 136.394 1.00 73.18  ?  302 THR A CB  1 
ATOM   1418 O OG1 . THR A 1 302 ? 133.711 131.225 135.975 1.00 73.18  ?  302 THR A OG1 1 
ATOM   1419 C CG2 . THR A 1 302 ? 133.813 128.955 135.168 1.00 73.18  ?  302 THR A CG2 1 
ATOM   1420 N N   . ARG A 1 303 ? 133.257 127.805 138.697 1.00 72.82  ?  303 ARG A N   1 
ATOM   1421 C CA  . ARG A 1 303 ? 133.337 126.436 139.192 1.00 72.82  ?  303 ARG A CA  1 
ATOM   1422 C C   . ARG A 1 303 ? 131.990 125.966 139.725 1.00 72.82  ?  303 ARG A C   1 
ATOM   1423 O O   . ARG A 1 303 ? 131.575 124.832 139.467 1.00 72.82  ?  303 ARG A O   1 
ATOM   1424 C CB  . ARG A 1 303 ? 134.411 126.333 140.275 1.00 72.82  ?  303 ARG A CB  1 
ATOM   1425 C CG  . ARG A 1 303 ? 134.664 124.916 140.763 1.00 72.82  ?  303 ARG A CG  1 
ATOM   1426 C CD  . ARG A 1 303 ? 135.859 124.856 141.701 1.00 72.82  ?  303 ARG A CD  1 
ATOM   1427 N NE  . ARG A 1 303 ? 135.643 125.632 142.920 1.00 72.82  ?  303 ARG A NE  1 
ATOM   1428 C CZ  . ARG A 1 303 ? 135.062 125.162 144.021 1.00 72.82  ?  303 ARG A CZ  1 
ATOM   1429 N NH1 . ARG A 1 303 ? 134.627 123.909 144.073 1.00 72.82  1  303 ARG A NH1 1 
ATOM   1430 N NH2 . ARG A 1 303 ? 134.913 125.950 145.077 1.00 72.82  ?  303 ARG A NH2 1 
ATOM   1431 N N   . ALA A 1 304 ? 131.284 126.830 140.457 1.00 71.52  ?  304 ALA A N   1 
ATOM   1432 C CA  . ALA A 1 304 ? 129.991 126.444 141.011 1.00 71.52  ?  304 ALA A CA  1 
ATOM   1433 C C   . ALA A 1 304 ? 128.975 126.183 139.906 1.00 71.52  ?  304 ALA A C   1 
ATOM   1434 O O   . ALA A 1 304 ? 128.262 125.171 139.928 1.00 71.52  ?  304 ALA A O   1 
ATOM   1435 C CB  . ALA A 1 304 ? 129.485 127.528 141.963 1.00 71.52  ?  304 ALA A CB  1 
ATOM   1436 N N   . LYS A 1 305 ? 128.889 127.090 138.928 1.00 70.58  ?  305 LYS A N   1 
ATOM   1437 C CA  . LYS A 1 305 ? 127.915 126.907 137.857 1.00 70.58  ?  305 LYS A CA  1 
ATOM   1438 C C   . LYS A 1 305 ? 128.238 125.669 137.030 1.00 70.58  ?  305 LYS A C   1 
ATOM   1439 O O   . LYS A 1 305 ? 127.332 124.932 136.623 1.00 70.58  ?  305 LYS A O   1 
ATOM   1440 C CB  . LYS A 1 305 ? 127.856 128.153 136.972 1.00 70.58  ?  305 LYS A CB  1 
ATOM   1441 C CG  . LYS A 1 305 ? 129.134 128.449 136.207 1.00 70.58  ?  305 LYS A CG  1 
ATOM   1442 C CD  . LYS A 1 305 ? 128.977 129.649 135.281 1.00 70.58  ?  305 LYS A CD  1 
ATOM   1443 C CE  . LYS A 1 305 ? 128.752 130.940 136.055 1.00 70.58  ?  305 LYS A CE  1 
ATOM   1444 N NZ  . LYS A 1 305 ? 128.680 132.123 135.154 1.00 70.58  1  305 LYS A NZ  1 
ATOM   1445 N N   . TYR A 1 306 ? 129.526 125.408 136.786 1.00 71.26  ?  306 TYR A N   1 
ATOM   1446 C CA  . TYR A 1 306 ? 129.892 124.223 136.019 1.00 71.26  ?  306 TYR A CA  1 
ATOM   1447 C C   . TYR A 1 306 ? 129.640 122.945 136.807 1.00 71.26  ?  306 TYR A C   1 
ATOM   1448 O O   . TYR A 1 306 ? 129.253 121.931 136.220 1.00 71.26  ?  306 TYR A O   1 
ATOM   1449 C CB  . TYR A 1 306 ? 131.353 124.308 135.580 1.00 71.26  ?  306 TYR A CB  1 
ATOM   1450 C CG  . TYR A 1 306 ? 131.535 124.993 134.244 1.00 71.26  ?  306 TYR A CG  1 
ATOM   1451 C CD1 . TYR A 1 306 ? 131.783 126.357 134.166 1.00 71.26  ?  306 TYR A CD1 1 
ATOM   1452 C CD2 . TYR A 1 306 ? 131.445 124.276 133.059 1.00 71.26  ?  306 TYR A CD2 1 
ATOM   1453 C CE1 . TYR A 1 306 ? 131.944 126.985 132.946 1.00 71.26  ?  306 TYR A CE1 1 
ATOM   1454 C CE2 . TYR A 1 306 ? 131.605 124.896 131.835 1.00 71.26  ?  306 TYR A CE2 1 
ATOM   1455 C CZ  . TYR A 1 306 ? 131.853 126.250 131.784 1.00 71.26  ?  306 TYR A CZ  1 
ATOM   1456 O OH  . TYR A 1 306 ? 132.012 126.870 130.566 1.00 71.26  ?  306 TYR A OH  1 
ATOM   1457 N N   . PHE A 1 307 ? 129.828 122.972 138.128 1.00 69.85  ?  307 PHE A N   1 
ATOM   1458 C CA  . PHE A 1 307 ? 129.477 121.812 138.940 1.00 69.85  ?  307 PHE A CA  1 
ATOM   1459 C C   . PHE A 1 307 ? 127.978 121.549 138.893 1.00 69.85  ?  307 PHE A C   1 
ATOM   1460 O O   . PHE A 1 307 ? 127.544 120.396 138.779 1.00 69.85  ?  307 PHE A O   1 
ATOM   1461 C CB  . PHE A 1 307 ? 129.940 122.024 140.382 1.00 69.85  ?  307 PHE A CB  1 
ATOM   1462 C CG  . PHE A 1 307 ? 129.428 120.987 141.342 1.00 69.85  ?  307 PHE A CG  1 
ATOM   1463 C CD1 . PHE A 1 307 ? 130.053 119.757 141.454 1.00 69.85  ?  307 PHE A CD1 1 
ATOM   1464 C CD2 . PHE A 1 307 ? 128.322 121.246 142.135 1.00 69.85  ?  307 PHE A CD2 1 
ATOM   1465 C CE1 . PHE A 1 307 ? 129.584 118.803 142.337 1.00 69.85  ?  307 PHE A CE1 1 
ATOM   1466 C CE2 . PHE A 1 307 ? 127.849 120.295 143.020 1.00 69.85  ?  307 PHE A CE2 1 
ATOM   1467 C CZ  . PHE A 1 307 ? 128.481 119.073 143.121 1.00 69.85  ?  307 PHE A CZ  1 
ATOM   1468 N N   . ILE A 1 308 ? 127.171 122.608 138.981 1.00 67.60  ?  308 ILE A N   1 
ATOM   1469 C CA  . ILE A 1 308 ? 125.721 122.443 138.892 1.00 67.60  ?  308 ILE A CA  1 
ATOM   1470 C C   . ILE A 1 308 ? 125.340 121.855 137.537 1.00 67.60  ?  308 ILE A C   1 
ATOM   1471 O O   . ILE A 1 308 ? 124.522 120.930 137.445 1.00 67.60  ?  308 ILE A O   1 
ATOM   1472 C CB  . ILE A 1 308 ? 125.012 123.785 139.146 1.00 67.60  ?  308 ILE A CB  1 
ATOM   1473 C CG1 . ILE A 1 308 ? 125.259 124.250 140.585 1.00 67.60  ?  308 ILE A CG1 1 
ATOM   1474 C CG2 . ILE A 1 308 ? 123.518 123.657 138.873 1.00 67.60  ?  308 ILE A CG2 1 
ATOM   1475 C CD1 . ILE A 1 308 ? 124.804 125.669 140.863 1.00 67.60  ?  308 ILE A CD1 1 
ATOM   1476 N N   . ARG A 1 309 ? 125.930 122.387 136.463 1.00 66.76  ?  309 ARG A N   1 
ATOM   1477 C CA  . ARG A 1 309 ? 125.611 121.890 135.129 1.00 66.76  ?  309 ARG A CA  1 
ATOM   1478 C C   . ARG A 1 309 ? 126.043 120.438 134.966 1.00 66.76  ?  309 ARG A C   1 
ATOM   1479 O O   . ARG A 1 309 ? 125.345 119.645 134.327 1.00 66.76  ?  309 ARG A O   1 
ATOM   1480 C CB  . ARG A 1 309 ? 126.274 122.764 134.065 1.00 66.76  ?  309 ARG A CB  1 
ATOM   1481 C CG  . ARG A 1 309 ? 125.760 122.506 132.656 1.00 66.76  ?  309 ARG A CG  1 
ATOM   1482 C CD  . ARG A 1 309 ? 126.591 123.226 131.607 1.00 66.76  ?  309 ARG A CD  1 
ATOM   1483 N NE  . ARG A 1 309 ? 127.930 122.658 131.482 1.00 66.76  ?  309 ARG A NE  1 
ATOM   1484 C CZ  . ARG A 1 309 ? 128.839 123.066 130.602 1.00 66.76  ?  309 ARG A CZ  1 
ATOM   1485 N NH1 . ARG A 1 309 ? 128.560 124.052 129.759 1.00 66.76  1  309 ARG A NH1 1 
ATOM   1486 N NH2 . ARG A 1 309 ? 130.030 122.485 130.563 1.00 66.76  ?  309 ARG A NH2 1 
ATOM   1487 N N   . LYS A 1 310 ? 127.189 120.069 135.541 1.00 69.68  ?  310 LYS A N   1 
ATOM   1488 C CA  . LYS A 1 310 ? 127.649 118.688 135.454 1.00 69.68  ?  310 LYS A CA  1 
ATOM   1489 C C   . LYS A 1 310 ? 126.719 117.755 136.216 1.00 69.68  ?  310 LYS A C   1 
ATOM   1490 O O   . LYS A 1 310 ? 126.408 116.658 135.740 1.00 69.68  ?  310 LYS A O   1 
ATOM   1491 C CB  . LYS A 1 310 ? 129.078 118.579 135.986 1.00 69.68  ?  310 LYS A CB  1 
ATOM   1492 C CG  . LYS A 1 310 ? 129.653 117.167 135.974 1.00 69.68  ?  310 LYS A CG  1 
ATOM   1493 C CD  . LYS A 1 310 ? 129.696 116.585 134.570 1.00 69.68  ?  310 LYS A CD  1 
ATOM   1494 C CE  . LYS A 1 310 ? 130.338 115.207 134.561 1.00 69.68  ?  310 LYS A CE  1 
ATOM   1495 N NZ  . LYS A 1 310 ? 130.386 114.622 133.192 1.00 69.68  1  310 LYS A NZ  1 
ATOM   1496 N N   . GLU A 1 311 ? 126.265 118.171 137.399 1.00 67.04  ?  311 GLU A N   1 
ATOM   1497 C CA  . GLU A 1 311 ? 125.305 117.361 138.141 1.00 67.04  ?  311 GLU A CA  1 
ATOM   1498 C C   . GLU A 1 311 ? 124.018 117.176 137.347 1.00 67.04  ?  311 GLU A C   1 
ATOM   1499 O O   . GLU A 1 311 ? 123.474 116.066 137.276 1.00 67.04  ?  311 GLU A O   1 
ATOM   1500 C CB  . GLU A 1 311 ? 125.010 118.005 139.496 1.00 67.04  ?  311 GLU A CB  1 
ATOM   1501 C CG  . GLU A 1 311 ? 126.189 118.001 140.458 1.00 67.04  ?  311 GLU A CG  1 
ATOM   1502 C CD  . GLU A 1 311 ? 126.566 116.605 140.917 1.00 67.04  ?  311 GLU A CD  1 
ATOM   1503 O OE1 . GLU A 1 311 ? 125.822 115.652 140.603 1.00 67.04  ?  311 GLU A OE1 1 
ATOM   1504 O OE2 . GLU A 1 311 ? 127.606 116.461 141.593 1.00 67.04  ?  311 GLU A OE2 1 
ATOM   1505 N N   . PHE A 1 312 ? 123.516 118.253 136.737 1.00 63.03  ?  312 PHE A N   1 
ATOM   1506 C CA  . PHE A 1 312 ? 122.290 118.141 135.953 1.00 63.03  ?  312 PHE A CA  1 
ATOM   1507 C C   . PHE A 1 312 ? 122.486 117.233 134.743 1.00 63.03  ?  312 PHE A C   1 
ATOM   1508 O O   . PHE A 1 312 ? 121.616 116.413 134.426 1.00 63.03  ?  312 PHE A O   1 
ATOM   1509 C CB  . PHE A 1 312 ? 121.815 119.526 135.513 1.00 63.03  ?  312 PHE A CB  1 
ATOM   1510 C CG  . PHE A 1 312 ? 120.980 120.234 136.543 1.00 63.03  ?  312 PHE A CG  1 
ATOM   1511 C CD1 . PHE A 1 312 ? 119.665 119.859 136.761 1.00 63.03  ?  312 PHE A CD1 1 
ATOM   1512 C CD2 . PHE A 1 312 ? 121.506 121.277 137.286 1.00 63.03  ?  312 PHE A CD2 1 
ATOM   1513 C CE1 . PHE A 1 312 ? 118.892 120.507 137.705 1.00 63.03  ?  312 PHE A CE1 1 
ATOM   1514 C CE2 . PHE A 1 312 ? 120.736 121.930 138.231 1.00 63.03  ?  312 PHE A CE2 1 
ATOM   1515 C CZ  . PHE A 1 312 ? 119.428 121.544 138.440 1.00 63.03  ?  312 PHE A CZ  1 
ATOM   1516 N N   . VAL A 1 313 ? 123.625 117.357 134.059 1.00 63.75  ?  313 VAL A N   1 
ATOM   1517 C CA  . VAL A 1 313 ? 123.877 116.519 132.891 1.00 63.75  ?  313 VAL A CA  1 
ATOM   1518 C C   . VAL A 1 313 ? 124.035 115.061 133.298 1.00 63.75  ?  313 VAL A C   1 
ATOM   1519 O O   . VAL A 1 313 ? 123.646 114.157 132.550 1.00 63.75  ?  313 VAL A O   1 
ATOM   1520 C CB  . VAL A 1 313 ? 125.115 117.028 132.128 1.00 63.75  ?  313 VAL A CB  1 
ATOM   1521 C CG1 . VAL A 1 313 ? 125.523 116.033 131.052 1.00 63.75  ?  313 VAL A CG1 1 
ATOM   1522 C CG2 . VAL A 1 313 ? 124.835 118.392 131.514 1.00 63.75  ?  313 VAL A CG2 1 
ATOM   1523 N N   . ASP A 1 314 ? 124.603 114.801 134.477 1.00 64.97  ?  314 ASP A N   1 
ATOM   1524 C CA  . ASP A 1 314 ? 124.717 113.427 134.950 1.00 64.97  ?  314 ASP A CA  1 
ATOM   1525 C C   . ASP A 1 314 ? 123.348 112.855 135.295 1.00 64.97  ?  314 ASP A C   1 
ATOM   1526 O O   . ASP A 1 314 ? 123.061 111.691 134.994 1.00 64.97  ?  314 ASP A O   1 
ATOM   1527 C CB  . ASP A 1 314 ? 125.647 113.368 136.162 1.00 64.97  ?  314 ASP A CB  1 
ATOM   1528 C CG  . ASP A 1 314 ? 126.060 111.950 136.517 1.00 64.97  ?  314 ASP A CG  1 
ATOM   1529 O OD1 . ASP A 1 314 ? 125.279 111.012 136.253 1.00 64.97  ?  314 ASP A OD1 1 
ATOM   1530 O OD2 . ASP A 1 314 ? 127.169 111.774 137.063 1.00 64.97  ?  314 ASP A OD2 1 
ATOM   1531 N N   . ILE A 1 315 ? 122.489 113.661 135.924 1.00 61.83  ?  315 ILE A N   1 
ATOM   1532 C CA  . ILE A 1 315 ? 121.143 113.193 136.236 1.00 61.83  ?  315 ILE A CA  1 
ATOM   1533 C C   . ILE A 1 315 ? 120.339 112.976 134.960 1.00 61.83  ?  315 ILE A C   1 
ATOM   1534 O O   . ILE A 1 315 ? 119.447 112.120 134.918 1.00 61.83  ?  315 ILE A O   1 
ATOM   1535 C CB  . ILE A 1 315 ? 120.440 114.184 137.182 1.00 61.83  ?  315 ILE A CB  1 
ATOM   1536 C CG1 . ILE A 1 315 ? 121.159 114.225 138.534 1.00 61.83  ?  315 ILE A CG1 1 
ATOM   1537 C CG2 . ILE A 1 315 ? 118.975 113.798 137.361 1.00 61.83  ?  315 ILE A CG2 1 
ATOM   1538 C CD1 . ILE A 1 315 ? 120.684 115.332 139.453 1.00 61.83  ?  315 ILE A CD1 1 
ATOM   1539 N N   . SER A 1 316 ? 120.635 113.736 133.904 1.00 62.68  ?  316 SER A N   1 
ATOM   1540 C CA  . SER A 1 316 ? 119.890 113.609 132.655 1.00 62.68  ?  316 SER A CA  1 
ATOM   1541 C C   . SER A 1 316 ? 120.351 112.397 131.852 1.00 62.68  ?  316 SER A C   1 
ATOM   1542 O O   . SER A 1 316 ? 119.549 111.521 131.511 1.00 62.68  ?  316 SER A O   1 
ATOM   1543 C CB  . SER A 1 316 ? 120.040 114.887 131.826 1.00 62.68  ?  316 SER A CB  1 
ATOM   1544 O OG  . SER A 1 316 ? 119.577 116.018 132.542 1.00 62.68  ?  316 SER A OG  1 
ATOM   1545 N N   . THR A 1 317 ? 121.649 112.333 131.539 1.00 63.24  ?  317 THR A N   1 
ATOM   1546 C CA  . THR A 1 317 ? 122.161 111.252 130.702 1.00 63.24  ?  317 THR A CA  1 
ATOM   1547 C C   . THR A 1 317 ? 121.861 109.882 131.296 1.00 63.24  ?  317 THR A C   1 
ATOM   1548 O O   . THR A 1 317 ? 121.842 108.883 130.567 1.00 63.24  ?  317 THR A O   1 
ATOM   1549 C CB  . THR A 1 317 ? 123.667 111.415 130.497 1.00 63.24  ?  317 THR A CB  1 
ATOM   1550 O OG1 . THR A 1 317 ? 124.324 111.474 131.769 1.00 63.24  ?  317 THR A OG1 1 
ATOM   1551 C CG2 . THR A 1 317 ? 123.967 112.685 129.711 1.00 63.24  ?  317 THR A CG2 1 
ATOM   1552 N N   . ALA A 1 318 ? 121.630 109.809 132.606 1.00 63.35  ?  318 ALA A N   1 
ATOM   1553 C CA  . ALA A 1 318 ? 121.292 108.544 133.245 1.00 63.35  ?  318 ALA A CA  1 
ATOM   1554 C C   . ALA A 1 318 ? 120.051 107.942 132.599 1.00 63.35  ?  318 ALA A C   1 
ATOM   1555 O O   . ALA A 1 318 ? 118.957 108.509 132.693 1.00 63.35  ?  318 ALA A O   1 
ATOM   1556 C CB  . ALA A 1 318 ? 121.070 108.742 134.746 1.00 63.35  ?  318 ALA A CB  1 
ATOM   1557 N N   . SER A 1 319 ? 120.213 106.796 131.938 1.00 67.84  ?  319 SER A N   1 
ATOM   1558 C CA  . SER A 1 319 ? 119.114 106.123 131.247 1.00 67.84  ?  319 SER A CA  1 
ATOM   1559 C C   . SER A 1 319 ? 118.535 106.993 130.135 1.00 67.84  ?  319 SER A C   1 
ATOM   1560 O O   . SER A 1 319 ? 117.342 106.917 129.831 1.00 67.84  ?  319 SER A O   1 
ATOM   1561 C CB  . SER A 1 319 ? 118.013 105.712 132.230 1.00 67.84  ?  319 SER A CB  1 
ATOM   1562 O OG  . SER A 1 319 ? 116.976 105.009 131.569 1.00 67.84  ?  319 SER A OG  1 
ATOM   1563 N N   . GLY A 1 320 ? 119.375 107.825 129.519 1.00 68.33  ?  320 GLY A N   1 
ATOM   1564 C CA  . GLY A 1 320 ? 118.892 108.684 128.449 1.00 68.33  ?  320 GLY A CA  1 
ATOM   1565 C C   . GLY A 1 320 ? 118.663 107.927 127.154 1.00 68.33  ?  320 GLY A C   1 
ATOM   1566 O O   . GLY A 1 320 ? 117.615 108.064 126.518 1.00 68.33  ?  320 GLY A O   1 
ATOM   1567 N N   . ASP A 1 321 ? 119.643 107.122 126.745 1.00 70.12  ?  321 ASP A N   1 
ATOM   1568 C CA  . ASP A 1 321 ? 119.593 106.300 125.540 1.00 70.12  ?  321 ASP A CA  1 
ATOM   1569 C C   . ASP A 1 321 ? 119.559 107.125 124.261 1.00 70.12  ?  321 ASP A C   1 
ATOM   1570 O O   . ASP A 1 321 ? 119.308 106.571 123.183 1.00 70.12  ?  321 ASP A O   1 
ATOM   1571 C CB  . ASP A 1 321 ? 118.389 105.351 125.556 1.00 70.12  ?  321 ASP A CB  1 
ATOM   1572 C CG  . ASP A 1 321 ? 118.375 104.448 126.773 1.00 70.12  ?  321 ASP A CG  1 
ATOM   1573 O OD1 . ASP A 1 321 ? 119.466 104.125 127.288 1.00 70.12  ?  321 ASP A OD1 1 
ATOM   1574 O OD2 . ASP A 1 321 ? 117.273 104.060 127.215 1.00 70.12  ?  321 ASP A OD2 1 
ATOM   1575 N N   . GLY A 1 322 ? 119.804 108.434 124.342 1.00 68.85  ?  322 GLY A N   1 
ATOM   1576 C CA  . GLY A 1 322 ? 119.797 109.294 123.179 1.00 68.85  ?  322 GLY A CA  1 
ATOM   1577 C C   . GLY A 1 322 ? 118.428 109.719 122.696 1.00 68.85  ?  322 GLY A C   1 
ATOM   1578 O O   . GLY A 1 322 ? 118.319 110.753 122.025 1.00 68.85  ?  322 GLY A O   1 
ATOM   1579 N N   . ARG A 1 323 ? 117.376 108.957 123.009 1.00 66.88  ?  323 ARG A N   1 
ATOM   1580 C CA  . ARG A 1 323 ? 116.033 109.344 122.589 1.00 66.88  ?  323 ARG A CA  1 
ATOM   1581 C C   . ARG A 1 323 ? 115.656 110.724 123.111 1.00 66.88  ?  323 ARG A C   1 
ATOM   1582 O O   . ARG A 1 323 ? 114.841 111.419 122.494 1.00 66.88  ?  323 ARG A O   1 
ATOM   1583 C CB  . ARG A 1 323 ? 115.015 108.302 123.057 1.00 66.88  ?  323 ARG A CB  1 
ATOM   1584 C CG  . ARG A 1 323 ? 115.145 107.907 124.521 1.00 66.88  ?  323 ARG A CG  1 
ATOM   1585 C CD  . ARG A 1 323 ? 114.053 106.934 124.932 1.00 66.88  ?  323 ARG A CD  1 
ATOM   1586 N NE  . ARG A 1 323 ? 114.357 106.273 126.199 1.00 66.88  ?  323 ARG A NE  1 
ATOM   1587 C CZ  . ARG A 1 323 ? 114.210 106.835 127.395 1.00 66.88  ?  323 ARG A CZ  1 
ATOM   1588 N NH1 . ARG A 1 323 ? 113.767 108.080 127.501 1.00 66.88  1  323 ARG A NH1 1 
ATOM   1589 N NH2 . ARG A 1 323 ? 114.513 106.151 128.489 1.00 66.88  ?  323 ARG A NH2 1 
ATOM   1590 N N   . HIS A 1 324 ? 116.232 111.138 124.237 1.00 62.11  ?  324 HIS A N   1 
ATOM   1591 C CA  . HIS A 1 324 ? 115.997 112.469 124.777 1.00 62.11  ?  324 HIS A CA  1 
ATOM   1592 C C   . HIS A 1 324 ? 117.250 112.929 125.505 1.00 62.11  ?  324 HIS A C   1 
ATOM   1593 O O   . HIS A 1 324 ? 117.825 112.180 126.300 1.00 62.11  ?  324 HIS A O   1 
ATOM   1594 C CB  . HIS A 1 324 ? 114.791 112.492 125.726 1.00 62.11  ?  324 HIS A CB  1 
ATOM   1595 C CG  . HIS A 1 324 ? 114.932 111.587 126.911 1.00 62.11  ?  324 HIS A CG  1 
ATOM   1596 N ND1 . HIS A 1 324 ? 114.801 110.218 126.825 1.00 62.11  ?  324 HIS A ND1 1 
ATOM   1597 C CD2 . HIS A 1 324 ? 115.198 111.859 128.211 1.00 62.11  ?  324 HIS A CD2 1 
ATOM   1598 C CE1 . HIS A 1 324 ? 114.978 109.685 128.020 1.00 62.11  ?  324 HIS A CE1 1 
ATOM   1599 N NE2 . HIS A 1 324 ? 115.220 110.658 128.880 1.00 62.11  ?  324 HIS A NE2 1 
ATOM   1600 N N   . ILE A 1 325 ? 117.669 114.161 125.225 1.00 60.34  ?  325 ILE A N   1 
ATOM   1601 C CA  . ILE A 1 325 ? 118.863 114.741 125.823 1.00 60.34  ?  325 ILE A CA  1 
ATOM   1602 C C   . ILE A 1 325 ? 118.498 116.079 126.447 1.00 60.34  ?  325 ILE A C   1 
ATOM   1603 O O   . ILE A 1 325 ? 117.584 116.772 125.990 1.00 60.34  ?  325 ILE A O   1 
ATOM   1604 C CB  . ILE A 1 325 ? 119.999 114.914 124.790 1.00 60.34  ?  325 ILE A CB  1 
ATOM   1605 C CG1 . ILE A 1 325 ? 119.520 115.754 123.602 1.00 60.34  ?  325 ILE A CG1 1 
ATOM   1606 C CG2 . ILE A 1 325 ? 120.494 113.555 124.320 1.00 60.34  ?  325 ILE A CG2 1 
ATOM   1607 C CD1 . ILE A 1 325 ? 120.585 116.002 122.555 1.00 60.34  ?  325 ILE A CD1 1 
ATOM   1608 N N   . CYS A 1 326 ? 119.223 116.439 127.501 1.00 59.60  ?  326 CYS A N   1 
ATOM   1609 C CA  . CYS A 1 326 ? 118.977 117.679 128.218 1.00 59.60  ?  326 CYS A CA  1 
ATOM   1610 C C   . CYS A 1 326 ? 119.693 118.844 127.541 1.00 59.60  ?  326 CYS A C   1 
ATOM   1611 O O   . CYS A 1 326 ? 120.701 118.674 126.851 1.00 59.60  ?  326 CYS A O   1 
ATOM   1612 C CB  . CYS A 1 326 ? 119.436 117.557 129.672 1.00 59.60  ?  326 CYS A CB  1 
ATOM   1613 S SG  . CYS A 1 326 ? 119.261 119.078 130.635 1.00 59.60  ?  326 CYS A SG  1 
ATOM   1614 N N   . TYR A 1 327 ? 119.150 120.042 127.750 1.00 59.91  ?  327 TYR A N   1 
ATOM   1615 C CA  . TYR A 1 327 ? 119.707 121.283 127.213 1.00 59.91  ?  327 TYR A CA  1 
ATOM   1616 C C   . TYR A 1 327 ? 119.809 122.280 128.359 1.00 59.91  ?  327 TYR A C   1 
ATOM   1617 O O   . TYR A 1 327 ? 118.854 123.015 128.644 1.00 59.91  ?  327 TYR A O   1 
ATOM   1618 C CB  . TYR A 1 327 ? 118.847 121.834 126.074 1.00 59.91  ?  327 TYR A CB  1 
ATOM   1619 C CG  . TYR A 1 327 ? 118.803 120.948 124.850 1.00 59.91  ?  327 TYR A CG  1 
ATOM   1620 C CD1 . TYR A 1 327 ? 117.854 119.941 124.732 1.00 59.91  ?  327 TYR A CD1 1 
ATOM   1621 C CD2 . TYR A 1 327 ? 119.706 121.121 123.810 1.00 59.91  ?  327 TYR A CD2 1 
ATOM   1622 C CE1 . TYR A 1 327 ? 117.808 119.131 123.615 1.00 59.91  ?  327 TYR A CE1 1 
ATOM   1623 C CE2 . TYR A 1 327 ? 119.668 120.316 122.689 1.00 59.91  ?  327 TYR A CE2 1 
ATOM   1624 C CZ  . TYR A 1 327 ? 118.717 119.322 122.597 1.00 59.91  ?  327 TYR A CZ  1 
ATOM   1625 O OH  . TYR A 1 327 ? 118.675 118.517 121.482 1.00 59.91  ?  327 TYR A OH  1 
ATOM   1626 N N   . PRO A 1 328 ? 120.938 122.301 129.068 1.00 61.06  ?  328 PRO A N   1 
ATOM   1627 C CA  . PRO A 1 328 ? 121.119 123.297 130.132 1.00 61.06  ?  328 PRO A CA  1 
ATOM   1628 C C   . PRO A 1 328 ? 121.605 124.625 129.569 1.00 61.06  ?  328 PRO A C   1 
ATOM   1629 O O   . PRO A 1 328 ? 122.434 124.667 128.657 1.00 61.06  ?  328 PRO A O   1 
ATOM   1630 C CB  . PRO A 1 328 ? 122.168 122.654 131.051 1.00 61.06  ?  328 PRO A CB  1 
ATOM   1631 C CG  . PRO A 1 328 ? 122.344 121.240 130.557 1.00 61.06  ?  328 PRO A CG  1 
ATOM   1632 C CD  . PRO A 1 328 ? 121.982 121.267 129.112 1.00 61.06  ?  328 PRO A CD  1 
ATOM   1633 N N   . HIS A 1 329 ? 121.081 125.717 130.123 1.00 62.68  ?  329 HIS A N   1 
ATOM   1634 C CA  . HIS A 1 329 ? 121.480 127.059 129.721 1.00 62.68  ?  329 HIS A CA  1 
ATOM   1635 C C   . HIS A 1 329 ? 121.415 127.981 130.929 1.00 62.68  ?  329 HIS A C   1 
ATOM   1636 O O   . HIS A 1 329 ? 120.410 127.998 131.646 1.00 62.68  ?  329 HIS A O   1 
ATOM   1637 C CB  . HIS A 1 329 ? 120.583 127.595 128.599 1.00 62.68  ?  329 HIS A CB  1 
ATOM   1638 C CG  . HIS A 1 329 ? 120.663 126.801 127.332 1.00 62.68  ?  329 HIS A CG  1 
ATOM   1639 N ND1 . HIS A 1 329 ? 121.574 127.078 126.337 1.00 62.68  ?  329 HIS A ND1 1 
ATOM   1640 C CD2 . HIS A 1 329 ? 119.946 125.736 126.900 1.00 62.68  ?  329 HIS A CD2 1 
ATOM   1641 C CE1 . HIS A 1 329 ? 121.415 126.220 125.345 1.00 62.68  ?  329 HIS A CE1 1 
ATOM   1642 N NE2 . HIS A 1 329 ? 120.434 125.395 125.662 1.00 62.68  ?  329 HIS A NE2 1 
ATOM   1643 N N   . PHE A 1 330 ? 122.485 128.742 131.149 1.00 66.74  ?  330 PHE A N   1 
ATOM   1644 C CA  . PHE A 1 330 ? 122.550 129.682 132.263 1.00 66.74  ?  330 PHE A CA  1 
ATOM   1645 C C   . PHE A 1 330 ? 121.775 130.939 131.891 1.00 66.74  ?  330 PHE A C   1 
ATOM   1646 O O   . PHE A 1 330 ? 122.226 131.733 131.058 1.00 66.74  ?  330 PHE A O   1 
ATOM   1647 C CB  . PHE A 1 330 ? 124.002 130.010 132.598 1.00 66.74  ?  330 PHE A CB  1 
ATOM   1648 C CG  . PHE A 1 330 ? 124.860 128.798 132.825 1.00 66.74  ?  330 PHE A CG  1 
ATOM   1649 C CD1 . PHE A 1 330 ? 124.849 128.144 134.045 1.00 66.74  ?  330 PHE A CD1 1 
ATOM   1650 C CD2 . PHE A 1 330 ? 125.680 128.315 131.819 1.00 66.74  ?  330 PHE A CD2 1 
ATOM   1651 C CE1 . PHE A 1 330 ? 125.637 127.029 134.256 1.00 66.74  ?  330 PHE A CE1 1 
ATOM   1652 C CE2 . PHE A 1 330 ? 126.471 127.200 132.026 1.00 66.74  ?  330 PHE A CE2 1 
ATOM   1653 C CZ  . PHE A 1 330 ? 126.449 126.558 133.246 1.00 66.74  ?  330 PHE A CZ  1 
ATOM   1654 N N   . THR A 1 331 ? 120.608 131.123 132.503 1.00 67.08  ?  331 THR A N   1 
ATOM   1655 C CA  . THR A 1 331 ? 119.735 132.254 132.221 1.00 67.08  ?  331 THR A CA  1 
ATOM   1656 C C   . THR A 1 331 ? 119.820 133.260 133.360 1.00 67.08  ?  331 THR A C   1 
ATOM   1657 O O   . THR A 1 331 ? 119.712 132.886 134.533 1.00 67.08  ?  331 THR A O   1 
ATOM   1658 C CB  . THR A 1 331 ? 118.287 131.796 132.035 1.00 67.08  ?  331 THR A CB  1 
ATOM   1659 O OG1 . THR A 1 331 ? 117.794 131.243 133.262 1.00 67.08  ?  331 THR A OG1 1 
ATOM   1660 C CG2 . THR A 1 331 ? 118.198 130.746 130.941 1.00 67.08  ?  331 THR A CG2 1 
ATOM   1661 N N   . CYS A 1 332 ? 120.016 134.529 133.013 1.00 70.86  ?  332 CYS A N   1 
ATOM   1662 C CA  . CYS A 1 332 ? 120.068 135.593 134.001 1.00 70.86  ?  332 CYS A CA  1 
ATOM   1663 C C   . CYS A 1 332 ? 118.656 136.087 134.313 1.00 70.86  ?  332 CYS A C   1 
ATOM   1664 O O   . CYS A 1 332 ? 117.663 135.624 133.744 1.00 70.86  ?  332 CYS A O   1 
ATOM   1665 C CB  . CYS A 1 332 ? 120.953 136.734 133.505 1.00 70.86  ?  332 CYS A CB  1 
ATOM   1666 S SG  . CYS A 1 332 ? 122.663 136.253 133.168 1.00 70.86  ?  332 CYS A SG  1 
ATOM   1667 N N   . SER A 1 333 ? 118.564 137.045 135.235 1.00 70.57  ?  333 SER A N   1 
ATOM   1668 C CA  . SER A 1 333 ? 117.279 137.602 135.634 1.00 70.57  ?  333 SER A CA  1 
ATOM   1669 C C   . SER A 1 333 ? 116.816 138.740 134.736 1.00 70.57  ?  333 SER A C   1 
ATOM   1670 O O   . SER A 1 333 ? 115.628 139.082 134.759 1.00 70.57  ?  333 SER A O   1 
ATOM   1671 C CB  . SER A 1 333 ? 117.349 138.103 137.081 1.00 70.57  ?  333 SER A CB  1 
ATOM   1672 O OG  . SER A 1 333 ? 117.670 137.048 137.971 1.00 70.57  ?  333 SER A OG  1 
ATOM   1673 N N   . VAL A 1 334 ? 117.719 139.333 133.951 1.00 72.39  ?  334 VAL A N   1 
ATOM   1674 C CA  . VAL A 1 334 ? 117.381 140.449 133.077 1.00 72.39  ?  334 VAL A CA  1 
ATOM   1675 C C   . VAL A 1 334 ? 117.781 140.204 131.631 1.00 72.39  ?  334 VAL A C   1 
ATOM   1676 O O   . VAL A 1 334 ? 117.482 141.033 130.770 1.00 72.39  ?  334 VAL A O   1 
ATOM   1677 C CB  . VAL A 1 334 ? 118.016 141.760 133.589 1.00 72.39  ?  334 VAL A CB  1 
ATOM   1678 C CG1 . VAL A 1 334 ? 119.533 141.715 133.444 1.00 72.39  ?  334 VAL A CG1 1 
ATOM   1679 C CG2 . VAL A 1 334 ? 117.433 142.966 132.861 1.00 72.39  ?  334 VAL A CG2 1 
ATOM   1680 N N   . ASP A 1 335 ? 118.442 139.086 131.328 1.00 71.68  ?  335 ASP A N   1 
ATOM   1681 C CA  . ASP A 1 335 ? 118.870 138.798 129.965 1.00 71.68  ?  335 ASP A CA  1 
ATOM   1682 C C   . ASP A 1 335 ? 117.679 138.760 129.015 1.00 71.68  ?  335 ASP A C   1 
ATOM   1683 O O   . ASP A 1 335 ? 116.816 137.883 129.123 1.00 71.68  ?  335 ASP A O   1 
ATOM   1684 C CB  . ASP A 1 335 ? 119.633 137.472 129.913 1.00 71.68  ?  335 ASP A CB  1 
ATOM   1685 C CG  . ASP A 1 335 ? 118.856 136.325 130.532 1.00 71.68  ?  335 ASP A CG  1 
ATOM   1686 O OD1 . ASP A 1 335 ? 117.793 136.581 131.136 1.00 71.68  ?  335 ASP A OD1 1 
ATOM   1687 O OD2 . ASP A 1 335 ? 119.309 135.167 130.414 1.00 71.68  ?  335 ASP A OD2 1 
ATOM   1688 N N   . THR A 1 336 ? 117.625 139.710 128.078 1.00 70.67  ?  336 THR A N   1 
ATOM   1689 C CA  . THR A 1 336 ? 116.521 139.743 127.126 1.00 70.67  ?  336 THR A CA  1 
ATOM   1690 C C   . THR A 1 336 ? 116.560 138.551 126.178 1.00 70.67  ?  336 THR A C   1 
ATOM   1691 O O   . THR A 1 336 ? 115.520 138.154 125.642 1.00 70.67  ?  336 THR A O   1 
ATOM   1692 C CB  . THR A 1 336 ? 116.550 141.049 126.330 1.00 70.67  ?  336 THR A CB  1 
ATOM   1693 O OG1 . THR A 1 336 ? 116.505 142.163 127.231 1.00 70.67  ?  336 THR A OG1 1 
ATOM   1694 C CG2 . THR A 1 336 ? 115.365 141.124 125.377 1.00 70.67  ?  336 THR A CG2 1 
ATOM   1695 N N   . GLU A 1 337 ? 117.740 137.970 125.960 1.00 68.69  ?  337 GLU A N   1 
ATOM   1696 C CA  . GLU A 1 337 ? 117.887 136.812 125.078 1.00 68.69  ?  337 GLU A CA  1 
ATOM   1697 C C   . GLU A 1 337 ? 117.445 135.535 125.800 1.00 68.69  ?  337 GLU A C   1 
ATOM   1698 O O   . GLU A 1 337 ? 118.205 134.587 125.993 1.00 68.69  ?  337 GLU A O   1 
ATOM   1699 C CB  . GLU A 1 337 ? 119.325 136.703 124.586 1.00 68.69  ?  337 GLU A CB  1 
ATOM   1700 C CG  . GLU A 1 337 ? 120.372 136.627 125.691 1.00 68.69  ?  337 GLU A CG  1 
ATOM   1701 C CD  . GLU A 1 337 ? 121.776 136.444 125.150 1.00 68.69  ?  337 GLU A CD  1 
ATOM   1702 O OE1 . GLU A 1 337 ? 121.934 136.377 123.913 1.00 68.69  ?  337 GLU A OE1 1 
ATOM   1703 O OE2 . GLU A 1 337 ? 122.722 136.365 125.962 1.00 68.69  ?  337 GLU A OE2 1 
ATOM   1704 N N   . ASN A 1 338 ? 116.172 135.527 126.193 1.00 66.52  ?  338 ASN A N   1 
ATOM   1705 C CA  . ASN A 1 338 ? 115.578 134.410 126.918 1.00 66.52  ?  338 ASN A CA  1 
ATOM   1706 C C   . ASN A 1 338 ? 114.798 133.476 126.001 1.00 66.52  ?  338 ASN A C   1 
ATOM   1707 O O   . ASN A 1 338 ? 114.986 132.258 126.052 1.00 66.52  ?  338 ASN A O   1 
ATOM   1708 C CB  . ASN A 1 338 ? 114.666 134.941 128.031 1.00 66.52  ?  338 ASN A CB  1 
ATOM   1709 C CG  . ASN A 1 338 ? 114.245 133.860 129.005 1.00 66.52  ?  338 ASN A CG  1 
ATOM   1710 O OD1 . ASN A 1 338 ? 114.740 132.734 128.955 1.00 66.52  ?  338 ASN A OD1 1 
ATOM   1711 N ND2 . ASN A 1 338 ? 113.332 134.201 129.907 1.00 66.52  ?  338 ASN A ND2 1 
ATOM   1712 N N   . ALA A 1 339 ? 113.919 134.027 125.159 1.00 64.82  ?  339 ALA A N   1 
ATOM   1713 C CA  . ALA A 1 339 ? 113.202 133.196 124.198 1.00 64.82  ?  339 ALA A CA  1 
ATOM   1714 C C   . ALA A 1 339 ? 114.130 132.674 123.109 1.00 64.82  ?  339 ALA A C   1 
ATOM   1715 O O   . ALA A 1 339 ? 113.859 131.623 122.515 1.00 64.82  ?  339 ALA A O   1 
ATOM   1716 C CB  . ALA A 1 339 ? 112.050 133.986 123.578 1.00 64.82  ?  339 ALA A CB  1 
ATOM   1717 N N   . ARG A 1 340 ? 115.219 133.393 122.827 1.00 63.49  ?  340 ARG A N   1 
ATOM   1718 C CA  . ARG A 1 340 ? 116.191 132.906 121.855 1.00 63.49  ?  340 ARG A CA  1 
ATOM   1719 C C   . ARG A 1 340 ? 116.768 131.566 122.290 1.00 63.49  ?  340 ARG A C   1 
ATOM   1720 O O   . ARG A 1 340 ? 117.068 130.707 121.452 1.00 63.49  ?  340 ARG A O   1 
ATOM   1721 C CB  . ARG A 1 340 ? 117.307 133.934 121.666 1.00 63.49  ?  340 ARG A CB  1 
ATOM   1722 C CG  . ARG A 1 340 ? 116.823 135.320 121.255 1.00 63.49  ?  340 ARG A CG  1 
ATOM   1723 C CD  . ARG A 1 340 ? 116.069 135.293 119.933 1.00 63.49  ?  340 ARG A CD  1 
ATOM   1724 N NE  . ARG A 1 340 ? 116.875 134.738 118.849 1.00 63.49  ?  340 ARG A NE  1 
ATOM   1725 C CZ  . ARG A 1 340 ? 116.454 134.604 117.595 1.00 63.49  ?  340 ARG A CZ  1 
ATOM   1726 N NH1 . ARG A 1 340 ? 115.230 134.985 117.254 1.00 63.49  1  340 ARG A NH1 1 
ATOM   1727 N NH2 . ARG A 1 340 ? 117.260 134.088 116.677 1.00 63.49  ?  340 ARG A NH2 1 
ATOM   1728 N N   . ARG A 1 341 ? 116.934 131.369 123.600 1.00 64.70  ?  341 ARG A N   1 
ATOM   1729 C CA  . ARG A 1 341 ? 117.394 130.077 124.097 1.00 64.70  ?  341 ARG A CA  1 
ATOM   1730 C C   . ARG A 1 341 ? 116.379 128.983 123.789 1.00 64.70  ?  341 ARG A C   1 
ATOM   1731 O O   . ARG A 1 341 ? 116.749 127.887 123.350 1.00 64.70  ?  341 ARG A O   1 
ATOM   1732 C CB  . ARG A 1 341 ? 117.655 130.160 125.601 1.00 64.70  ?  341 ARG A CB  1 
ATOM   1733 C CG  . ARG A 1 341 ? 118.658 131.231 125.996 1.00 64.70  ?  341 ARG A CG  1 
ATOM   1734 C CD  . ARG A 1 341 ? 118.799 131.324 127.504 1.00 64.70  ?  341 ARG A CD  1 
ATOM   1735 N NE  . ARG A 1 341 ? 119.698 132.402 127.911 1.00 64.70  ?  341 ARG A NE  1 
ATOM   1736 C CZ  . ARG A 1 341 ? 121.020 132.288 128.004 1.00 64.70  ?  341 ARG A CZ  1 
ATOM   1737 N NH1 . ARG A 1 341 ? 121.620 131.140 127.718 1.00 64.70  1  341 ARG A NH1 1 
ATOM   1738 N NH2 . ARG A 1 341 ? 121.747 133.330 128.384 1.00 64.70  ?  341 ARG A NH2 1 
ATOM   1739 N N   . ILE A 1 342 ? 115.094 129.261 124.023 1.00 62.22  ?  342 ILE A N   1 
ATOM   1740 C CA  . ILE A 1 342 ? 114.050 128.305 123.666 1.00 62.22  ?  342 ILE A CA  1 
ATOM   1741 C C   . ILE A 1 342 ? 114.124 127.973 122.184 1.00 62.22  ?  342 ILE A C   1 
ATOM   1742 O O   . ILE A 1 342 ? 114.007 126.808 121.786 1.00 62.22  ?  342 ILE A O   1 
ATOM   1743 C CB  . ILE A 1 342 ? 112.664 128.856 124.049 1.00 62.22  ?  342 ILE A CB  1 
ATOM   1744 C CG1 . ILE A 1 342 ? 112.472 128.801 125.566 1.00 62.22  ?  342 ILE A CG1 1 
ATOM   1745 C CG2 . ILE A 1 342 ? 111.565 128.078 123.320 1.00 62.22  ?  342 ILE A CG2 1 
ATOM   1746 C CD1 . ILE A 1 342 ? 111.203 129.477 126.058 1.00 62.22  ?  342 ILE A CD1 1 
ATOM   1747 N N   . PHE A 1 343 ? 114.302 128.992 121.342 1.00 61.91  ?  343 PHE A N   1 
ATOM   1748 C CA  . PHE A 1 343 ? 114.356 128.758 119.903 1.00 61.91  ?  343 PHE A CA  1 
ATOM   1749 C C   . PHE A 1 343 ? 115.537 127.867 119.539 1.00 61.91  ?  343 PHE A C   1 
ATOM   1750 O O   . PHE A 1 343 ? 115.388 126.887 118.800 1.00 61.91  ?  343 PHE A O   1 
ATOM   1751 C CB  . PHE A 1 343 ? 114.437 130.091 119.159 1.00 61.91  ?  343 PHE A CB  1 
ATOM   1752 C CG  . PHE A 1 343 ? 114.489 129.949 117.665 1.00 61.91  ?  343 PHE A CG  1 
ATOM   1753 C CD1 . PHE A 1 343 ? 113.322 129.868 116.922 1.00 61.91  ?  343 PHE A CD1 1 
ATOM   1754 C CD2 . PHE A 1 343 ? 115.704 129.896 117.002 1.00 61.91  ?  343 PHE A CD2 1 
ATOM   1755 C CE1 . PHE A 1 343 ? 113.367 129.736 115.548 1.00 61.91  ?  343 PHE A CE1 1 
ATOM   1756 C CE2 . PHE A 1 343 ? 115.754 129.765 115.627 1.00 61.91  ?  343 PHE A CE2 1 
ATOM   1757 C CZ  . PHE A 1 343 ? 114.584 129.684 114.900 1.00 61.91  ?  343 PHE A CZ  1 
ATOM   1758 N N   . ASN A 1 344 ? 116.726 128.197 120.052 1.00 62.64  ?  344 ASN A N   1 
ATOM   1759 C CA  . ASN A 1 344 ? 117.917 127.425 119.715 1.00 62.64  ?  344 ASN A CA  1 
ATOM   1760 C C   . ASN A 1 344 ? 117.826 125.995 120.231 1.00 62.64  ?  344 ASN A C   1 
ATOM   1761 O O   . ASN A 1 344 ? 118.349 125.073 119.594 1.00 62.64  ?  344 ASN A O   1 
ATOM   1762 C CB  . ASN A 1 344 ? 119.164 128.109 120.276 1.00 62.64  ?  344 ASN A CB  1 
ATOM   1763 C CG  . ASN A 1 344 ? 119.440 129.447 119.620 1.00 62.64  ?  344 ASN A CG  1 
ATOM   1764 O OD1 . ASN A 1 344 ? 119.973 129.510 118.512 1.00 62.64  ?  344 ASN A OD1 1 
ATOM   1765 N ND2 . ASN A 1 344 ? 119.084 130.527 120.305 1.00 62.64  ?  344 ASN A ND2 1 
ATOM   1766 N N   . ASP A 1 345 ? 117.172 125.786 121.375 1.00 61.34  ?  345 ASP A N   1 
ATOM   1767 C CA  . ASP A 1 345 ? 117.034 124.434 121.903 1.00 61.34  ?  345 ASP A CA  1 
ATOM   1768 C C   . ASP A 1 345 ? 116.015 123.628 121.106 1.00 61.34  ?  345 ASP A C   1 
ATOM   1769 O O   . ASP A 1 345 ? 116.282 122.478 120.733 1.00 61.34  ?  345 ASP A O   1 
ATOM   1770 C CB  . ASP A 1 345 ? 116.634 124.486 123.377 1.00 61.34  ?  345 ASP A CB  1 
ATOM   1771 C CG  . ASP A 1 345 ? 117.664 125.192 124.236 1.00 61.34  ?  345 ASP A CG  1 
ATOM   1772 O OD1 . ASP A 1 345 ? 118.864 125.140 123.892 1.00 61.34  ?  345 ASP A OD1 1 
ATOM   1773 O OD2 . ASP A 1 345 ? 117.274 125.801 125.254 1.00 61.34  ?  345 ASP A OD2 1 
ATOM   1774 N N   . CYS A 1 346 ? 114.846 124.214 120.835 1.00 60.51  ?  346 CYS A N   1 
ATOM   1775 C CA  . CYS A 1 346 ? 113.828 123.510 120.068 1.00 60.51  ?  346 CYS A CA  1 
ATOM   1776 C C   . CYS A 1 346 ? 114.296 123.223 118.649 1.00 60.51  ?  346 CYS A C   1 
ATOM   1777 O O   . CYS A 1 346 ? 113.889 122.217 118.060 1.00 60.51  ?  346 CYS A O   1 
ATOM   1778 C CB  . CYS A 1 346 ? 112.534 124.323 120.046 1.00 60.51  ?  346 CYS A CB  1 
ATOM   1779 S SG  . CYS A 1 346 ? 111.741 124.492 121.662 1.00 60.51  ?  346 CYS A SG  1 
ATOM   1780 N N   . LYS A 1 347 ? 115.148 124.080 118.083 1.00 59.59  ?  347 LYS A N   1 
ATOM   1781 C CA  . LYS A 1 347 ? 115.671 123.812 116.748 1.00 59.59  ?  347 LYS A CA  1 
ATOM   1782 C C   . LYS A 1 347 ? 116.453 122.506 116.730 1.00 59.59  ?  347 LYS A C   1 
ATOM   1783 O O   . LYS A 1 347 ? 116.212 121.635 115.887 1.00 59.59  ?  347 LYS A O   1 
ATOM   1784 C CB  . LYS A 1 347 ? 116.545 124.978 116.284 1.00 59.59  ?  347 LYS A CB  1 
ATOM   1785 C CG  . LYS A 1 347 ? 117.050 124.841 114.856 1.00 59.59  ?  347 LYS A CG  1 
ATOM   1786 C CD  . LYS A 1 347 ? 117.712 126.121 114.364 1.00 59.59  ?  347 LYS A CD  1 
ATOM   1787 C CE  . LYS A 1 347 ? 118.972 126.447 115.151 1.00 59.59  ?  347 LYS A CE  1 
ATOM   1788 N NZ  . LYS A 1 347 ? 119.650 127.667 114.633 1.00 59.59  1  347 LYS A NZ  1 
ATOM   1789 N N   . ASP A 1 348 ? 117.386 122.344 117.672 1.00 58.36  ?  348 ASP A N   1 
ATOM   1790 C CA  . ASP A 1 348 ? 118.149 121.103 117.750 1.00 58.36  ?  348 ASP A CA  1 
ATOM   1791 C C   . ASP A 1 348 ? 117.249 119.924 118.098 1.00 58.36  ?  348 ASP A C   1 
ATOM   1792 O O   . ASP A 1 348 ? 117.447 118.813 117.589 1.00 58.36  ?  348 ASP A O   1 
ATOM   1793 C CB  . ASP A 1 348 ? 119.269 121.245 118.781 1.00 58.36  ?  348 ASP A CB  1 
ATOM   1794 C CG  . ASP A 1 348 ? 120.197 120.045 118.805 1.00 58.36  ?  348 ASP A CG  1 
ATOM   1795 O OD1 . ASP A 1 348 ? 120.048 119.154 117.943 1.00 58.36  ?  348 ASP A OD1 1 
ATOM   1796 O OD2 . ASP A 1 348 ? 121.078 119.992 119.690 1.00 58.36  ?  348 ASP A OD2 1 
ATOM   1797 N N   . ILE A 1 349 ? 116.257 120.140 118.964 1.00 59.02  ?  349 ILE A N   1 
ATOM   1798 C CA  . ILE A 1 349 ? 115.351 119.055 119.332 1.00 59.02  ?  349 ILE A CA  1 
ATOM   1799 C C   . ILE A 1 349 ? 114.623 118.533 118.099 1.00 59.02  ?  349 ILE A C   1 
ATOM   1800 O O   . ILE A 1 349 ? 114.579 117.324 117.845 1.00 59.02  ?  349 ILE A O   1 
ATOM   1801 C CB  . ILE A 1 349 ? 114.364 119.523 120.416 1.00 59.02  ?  349 ILE A CB  1 
ATOM   1802 C CG1 . ILE A 1 349 ? 115.103 119.758 121.736 1.00 59.02  ?  349 ILE A CG1 1 
ATOM   1803 C CG2 . ILE A 1 349 ? 113.251 118.496 120.598 1.00 59.02  ?  349 ILE A CG2 1 
ATOM   1804 C CD1 . ILE A 1 349 ? 114.300 120.526 122.766 1.00 59.02  ?  349 ILE A CD1 1 
ATOM   1805 N N   . ILE A 1 350 ? 114.047 119.442 117.309 1.00 59.17  ?  350 ILE A N   1 
ATOM   1806 C CA  . ILE A 1 350 ? 113.323 119.032 116.111 1.00 59.17  ?  350 ILE A CA  1 
ATOM   1807 C C   . ILE A 1 350 ? 114.283 118.452 115.079 1.00 59.17  ?  350 ILE A C   1 
ATOM   1808 O O   . ILE A 1 350 ? 113.925 117.539 114.328 1.00 59.17  ?  350 ILE A O   1 
ATOM   1809 C CB  . ILE A 1 350 ? 112.522 120.215 115.537 1.00 59.17  ?  350 ILE A CB  1 
ATOM   1810 C CG1 . ILE A 1 350 ? 111.495 120.719 116.557 1.00 59.17  ?  350 ILE A CG1 1 
ATOM   1811 C CG2 . ILE A 1 350 ? 111.832 119.811 114.240 1.00 59.17  ?  350 ILE A CG2 1 
ATOM   1812 C CD1 . ILE A 1 350 ? 110.433 119.701 116.939 1.00 59.17  ?  350 ILE A CD1 1 
ATOM   1813 N N   . LEU A 1 351 ? 115.514 118.964 115.024 1.00 57.67  ?  351 LEU A N   1 
ATOM   1814 C CA  . LEU A 1 351 ? 116.501 118.406 114.107 1.00 57.67  ?  351 LEU A CA  1 
ATOM   1815 C C   . LEU A 1 351 ? 116.766 116.940 114.424 1.00 57.67  ?  351 LEU A C   1 
ATOM   1816 O O   . LEU A 1 351 ? 116.749 116.084 113.532 1.00 57.67  ?  351 LEU A O   1 
ATOM   1817 C CB  . LEU A 1 351 ? 117.795 119.218 114.177 1.00 57.67  ?  351 LEU A CB  1 
ATOM   1818 C CG  . LEU A 1 351 ? 118.966 118.712 113.332 1.00 57.67  ?  351 LEU A CG  1 
ATOM   1819 C CD1 . LEU A 1 351 ? 118.594 118.668 111.858 1.00 57.67  ?  351 LEU A CD1 1 
ATOM   1820 C CD2 . LEU A 1 351 ? 120.193 119.583 113.550 1.00 57.67  ?  351 LEU A CD2 1 
ATOM   1821 N N   . GLN A 1 352 ? 117.012 116.631 115.699 1.00 58.20  ?  352 GLN A N   1 
ATOM   1822 C CA  . GLN A 1 352 ? 117.236 115.242 116.084 1.00 58.20  ?  352 GLN A CA  1 
ATOM   1823 C C   . GLN A 1 352 ? 115.981 114.401 115.889 1.00 58.20  ?  352 GLN A C   1 
ATOM   1824 O O   . GLN A 1 352 ? 116.071 113.231 115.496 1.00 58.20  ?  352 GLN A O   1 
ATOM   1825 C CB  . GLN A 1 352 ? 117.708 115.161 117.537 1.00 58.20  ?  352 GLN A CB  1 
ATOM   1826 C CG  . GLN A 1 352 ? 118.945 115.995 117.844 1.00 58.20  ?  352 GLN A CG  1 
ATOM   1827 C CD  . GLN A 1 352 ? 120.090 115.723 116.892 1.00 58.20  ?  352 GLN A CD  1 
ATOM   1828 O OE1 . GLN A 1 352 ? 120.190 114.641 116.313 1.00 58.20  ?  352 GLN A OE1 1 
ATOM   1829 N NE2 . GLN A 1 352 ? 120.961 116.710 116.719 1.00 58.20  ?  352 GLN A NE2 1 
ATOM   1830 N N   . MET A 1 353 ? 114.804 114.977 116.143 1.00 60.18  ?  353 MET A N   1 
ATOM   1831 C CA  . MET A 1 353 ? 113.560 114.233 115.974 1.00 60.18  ?  353 MET A CA  1 
ATOM   1832 C C   . MET A 1 353 ? 113.314 113.883 114.511 1.00 60.18  ?  353 MET A C   1 
ATOM   1833 O O   . MET A 1 353 ? 112.767 112.817 114.210 1.00 60.18  ?  353 MET A O   1 
ATOM   1834 C CB  . MET A 1 353 ? 112.389 115.043 116.532 1.00 60.18  ?  353 MET A CB  1 
ATOM   1835 C CG  . MET A 1 353 ? 111.053 114.315 116.506 1.00 60.18  ?  353 MET A CG  1 
ATOM   1836 S SD  . MET A 1 353 ? 109.729 115.287 117.252 1.00 60.18  ?  353 MET A SD  1 
ATOM   1837 C CE  . MET A 1 353 ? 108.353 114.148 117.121 1.00 60.18  ?  353 MET A CE  1 
ATOM   1838 N N   . ASN A 1 354 ? 113.707 114.764 113.595 1.00 59.03  ?  354 ASN A N   1 
ATOM   1839 C CA  . ASN A 1 354 ? 113.570 114.516 112.167 1.00 59.03  ?  354 ASN A CA  1 
ATOM   1840 C C   . ASN A 1 354 ? 114.695 113.657 111.609 1.00 59.03  ?  354 ASN A C   1 
ATOM   1841 O O   . ASN A 1 354 ? 114.507 113.013 110.573 1.00 59.03  ?  354 ASN A O   1 
ATOM   1842 C CB  . ASN A 1 354 ? 113.508 115.842 111.402 1.00 59.03  ?  354 ASN A CB  1 
ATOM   1843 C CG  . ASN A 1 354 ? 112.341 116.708 111.832 1.00 59.03  ?  354 ASN A CG  1 
ATOM   1844 O OD1 . ASN A 1 354 ? 111.764 116.507 112.901 1.00 59.03  ?  354 ASN A OD1 1 
ATOM   1845 N ND2 . ASN A 1 354 ? 111.988 117.681 111.000 1.00 59.03  ?  354 ASN A ND2 1 
ATOM   1846 N N   . LEU A 1 355 ? 115.855 113.634 112.263 1.00 58.89  ?  355 LEU A N   1 
ATOM   1847 C CA  . LEU A 1 355 ? 116.923 112.721 111.877 1.00 58.89  ?  355 LEU A CA  1 
ATOM   1848 C C   . LEU A 1 355 ? 116.609 111.293 112.310 1.00 58.89  ?  355 LEU A C   1 
ATOM   1849 O O   . LEU A 1 355 ? 116.932 110.338 111.597 1.00 58.89  ?  355 LEU A O   1 
ATOM   1850 C CB  . LEU A 1 355 ? 118.256 113.178 112.480 1.00 58.89  ?  355 LEU A CB  1 
ATOM   1851 C CG  . LEU A 1 355 ? 118.882 114.437 111.876 1.00 58.89  ?  355 LEU A CG  1 
ATOM   1852 C CD1 . LEU A 1 355 ? 120.040 114.922 112.734 1.00 58.89  ?  355 LEU A CD1 1 
ATOM   1853 C CD2 . LEU A 1 355 ? 119.350 114.180 110.452 1.00 58.89  ?  355 LEU A CD2 1 
ATOM   1854 N N   . ARG A 1 356 ? 115.981 111.134 113.478 1.00 62.11  ?  356 ARG A N   1 
ATOM   1855 C CA  . ARG A 1 356 ? 115.610 109.804 113.948 1.00 62.11  ?  356 ARG A CA  1 
ATOM   1856 C C   . ARG A 1 356 ? 114.426 109.253 113.161 1.00 62.11  ?  356 ARG A C   1 
ATOM   1857 O O   . ARG A 1 356 ? 114.494 108.153 112.601 1.00 62.11  ?  356 ARG A O   1 
ATOM   1858 C CB  . ARG A 1 356 ? 115.283 109.852 115.442 1.00 62.11  ?  356 ARG A CB  1 
ATOM   1859 C CG  . ARG A 1 356 ? 115.163 108.479 116.088 1.00 62.11  ?  356 ARG A CG  1 
ATOM   1860 C CD  . ARG A 1 356 ? 114.676 108.564 117.528 1.00 62.11  ?  356 ARG A CD  1 
ATOM   1861 N NE  . ARG A 1 356 ? 113.222 108.444 117.628 1.00 62.11  ?  356 ARG A NE  1 
ATOM   1862 C CZ  . ARG A 1 356 ? 112.370 109.465 117.608 1.00 62.11  ?  356 ARG A CZ  1 
ATOM   1863 N NH1 . ARG A 1 356 ? 111.067 109.236 117.707 1.00 62.11  1  356 ARG A NH1 1 
ATOM   1864 N NH2 . ARG A 1 356 ? 112.806 110.713 117.493 1.00 62.11  ?  356 ARG A NH2 1 
ATOM   1865 N N   . GLU A 1 357 ? 113.327 110.009 113.110 1.00 62.24  ?  357 GLU A N   1 
ATOM   1866 C CA  . GLU A 1 357 ? 112.107 109.519 112.478 1.00 62.24  ?  357 GLU A CA  1 
ATOM   1867 C C   . GLU A 1 357 ? 112.290 109.222 110.996 1.00 62.24  ?  357 GLU A C   1 
ATOM   1868 O O   . GLU A 1 357 ? 111.624 108.322 110.473 1.00 62.24  ?  357 GLU A O   1 
ATOM   1869 C CB  . GLU A 1 357 ? 110.978 110.535 112.658 1.00 62.24  ?  357 GLU A CB  1 
ATOM   1870 C CG  . GLU A 1 357 ? 110.470 110.651 114.084 1.00 62.24  ?  357 GLU A CG  1 
ATOM   1871 C CD  . GLU A 1 357 ? 109.362 111.677 114.223 1.00 62.24  ?  357 GLU A CD  1 
ATOM   1872 O OE1 . GLU A 1 357 ? 109.072 112.380 113.232 1.00 62.24  ?  357 GLU A OE1 1 
ATOM   1873 O OE2 . GLU A 1 357 ? 108.780 111.779 115.323 1.00 62.24  ?  357 GLU A OE2 1 
ATOM   1874 N N   . TYR A 1 358 ? 113.169 109.948 110.309 1.00 57.90  ?  358 TYR A N   1 
ATOM   1875 C CA  . TYR A 1 358 ? 113.396 109.752 108.884 1.00 57.90  ?  358 TYR A CA  1 
ATOM   1876 C C   . TYR A 1 358 ? 114.586 108.844 108.601 1.00 57.90  ?  358 TYR A C   1 
ATOM   1877 O O   . TYR A 1 358 ? 115.013 108.740 107.446 1.00 57.90  ?  358 TYR A O   1 
ATOM   1878 C CB  . TYR A 1 358 ? 113.589 111.104 108.193 1.00 57.90  ?  358 TYR A CB  1 
ATOM   1879 C CG  . TYR A 1 358 ? 112.332 111.943 108.124 1.00 57.90  ?  358 TYR A CG  1 
ATOM   1880 C CD1 . TYR A 1 358 ? 111.861 112.617 109.243 1.00 57.90  ?  358 TYR A CD1 1 
ATOM   1881 C CD2 . TYR A 1 358 ? 111.620 112.067 106.939 1.00 57.90  ?  358 TYR A CD2 1 
ATOM   1882 C CE1 . TYR A 1 358 ? 110.715 113.386 109.185 1.00 57.90  ?  358 TYR A CE1 1 
ATOM   1883 C CE2 . TYR A 1 358 ? 110.472 112.834 106.871 1.00 57.90  ?  358 TYR A CE2 1 
ATOM   1884 C CZ  . TYR A 1 358 ? 110.024 113.492 107.997 1.00 57.90  ?  358 TYR A CZ  1 
ATOM   1885 O OH  . TYR A 1 358 ? 108.882 114.257 107.933 1.00 57.90  ?  358 TYR A OH  1 
ATOM   1886 N N   . ASN A 1 359 ? 115.126 108.184 109.622 1.00 60.12  ?  359 ASN A N   1 
ATOM   1887 C CA  . ASN A 1 359 ? 116.198 107.204 109.459 1.00 60.12  ?  359 ASN A CA  1 
ATOM   1888 C C   . ASN A 1 359 ? 117.433 107.836 108.814 1.00 60.12  ?  359 ASN A C   1 
ATOM   1889 O O   . ASN A 1 359 ? 117.842 107.487 107.705 1.00 60.12  ?  359 ASN A O   1 
ATOM   1890 C CB  . ASN A 1 359 ? 115.708 106.004 108.645 1.00 60.12  ?  359 ASN A CB  1 
ATOM   1891 C CG  . ASN A 1 359 ? 114.503 105.330 109.270 1.00 60.12  ?  359 ASN A CG  1 
ATOM   1892 O OD1 . ASN A 1 359 ? 113.421 105.298 108.683 1.00 60.12  ?  359 ASN A OD1 1 
ATOM   1893 N ND2 . ASN A 1 359 ? 114.683 104.788 110.468 1.00 60.12  ?  359 ASN A ND2 1 
ATOM   1894 N N   . LEU A 1 360 ? 118.026 108.790 109.537 1.00 58.53  ?  360 LEU A N   1 
ATOM   1895 C CA  . LEU A 1 360 ? 119.288 109.398 109.132 1.00 58.53  ?  360 LEU A CA  1 
ATOM   1896 C C   . LEU A 1 360 ? 120.299 109.459 110.272 1.00 58.53  ?  360 LEU A C   1 
ATOM   1897 O O   . LEU A 1 360 ? 121.379 110.034 110.092 1.00 58.53  ?  360 LEU A O   1 
ATOM   1898 C CB  . LEU A 1 360 ? 119.065 110.811 108.576 1.00 58.53  ?  360 LEU A CB  1 
ATOM   1899 C CG  . LEU A 1 360 ? 118.199 110.932 107.321 1.00 58.53  ?  360 LEU A CG  1 
ATOM   1900 C CD1 . LEU A 1 360 ? 116.750 111.169 107.695 1.00 58.53  ?  360 LEU A CD1 1 
ATOM   1901 C CD2 . LEU A 1 360 ? 118.712 112.046 106.421 1.00 58.53  ?  360 LEU A CD2 1 
ATOM   1902 N N   . VAL A 1 361 ? 119.986 108.889 111.431 1.00 61.69  ?  361 VAL A N   1 
ATOM   1903 C CA  . VAL A 1 361 ? 120.906 108.913 112.562 1.00 61.69  ?  361 VAL A CA  1 
ATOM   1904 C C   . VAL A 1 361 ? 120.672 107.700 113.458 1.00 61.69  ?  361 VAL A C   1 
ATOM   1905 O O   . VAL A 1 361 ? 119.569 107.486 113.960 1.00 61.69  ?  361 VAL A O   1 
ATOM   1906 C CB  . VAL A 1 361 ? 120.765 110.222 113.365 1.00 61.69  ?  361 VAL A CB  1 
ATOM   1907 C CG1 . VAL A 1 361 ? 119.397 110.304 114.032 1.00 61.69  ?  361 VAL A CG1 1 
ATOM   1908 C CG2 . VAL A 1 361 ? 121.878 110.336 114.397 1.00 61.69  ?  361 VAL A CG2 1 
ATOM   1909 N N   . GLU B 2 14  ? 96.501  110.374 172.736 1.00 122.93 ?  8   GLU B N   1 
ATOM   1910 C CA  . GLU B 2 14  ? 95.377  110.652 171.797 1.00 122.93 ?  8   GLU B CA  1 
ATOM   1911 C C   . GLU B 2 14  ? 95.692  110.130 170.400 1.00 122.93 ?  8   GLU B C   1 
ATOM   1912 O O   . GLU B 2 14  ? 95.039  109.207 169.912 1.00 122.93 ?  8   GLU B O   1 
ATOM   1913 C CB  . GLU B 2 14  ? 95.085  112.154 171.741 1.00 122.93 ?  8   GLU B CB  1 
ATOM   1914 C CG  . GLU B 2 14  ? 94.574  112.737 173.050 1.00 122.93 ?  8   GLU B CG  1 
ATOM   1915 C CD  . GLU B 2 14  ? 93.201  112.214 173.428 1.00 122.93 ?  8   GLU B CD  1 
ATOM   1916 O OE1 . GLU B 2 14  ? 92.578  111.519 172.598 1.00 122.93 ?  8   GLU B OE1 1 
ATOM   1917 O OE2 . GLU B 2 14  ? 92.745  112.499 174.555 1.00 122.93 ?  8   GLU B OE2 1 
ATOM   1918 N N   . LEU B 2 15  ? 96.699  110.728 169.758 1.00 123.60 ?  9   LEU B N   1 
ATOM   1919 C CA  . LEU B 2 15  ? 97.059  110.316 168.405 1.00 123.60 ?  9   LEU B CA  1 
ATOM   1920 C C   . LEU B 2 15  ? 97.374  108.826 168.347 1.00 123.60 ?  9   LEU B C   1 
ATOM   1921 O O   . LEU B 2 15  ? 96.932  108.127 167.428 1.00 123.60 ?  9   LEU B O   1 
ATOM   1922 C CB  . LEU B 2 15  ? 98.248  111.140 167.901 1.00 123.60 ?  9   LEU B CB  1 
ATOM   1923 C CG  . LEU B 2 15  ? 99.629  110.907 168.526 1.00 123.60 ?  9   LEU B CG  1 
ATOM   1924 C CD1 . LEU B 2 15  ? 100.686 111.678 167.752 1.00 123.60 ?  9   LEU B CD1 1 
ATOM   1925 C CD2 . LEU B 2 15  ? 99.661  111.301 169.997 1.00 123.60 ?  9   LEU B CD2 1 
ATOM   1926 N N   . ASP B 2 16  ? 98.125  108.318 169.326 1.00 123.36 ?  10  ASP B N   1 
ATOM   1927 C CA  . ASP B 2 16  ? 98.465  106.899 169.333 1.00 123.36 ?  10  ASP B CA  1 
ATOM   1928 C C   . ASP B 2 16  ? 97.223  106.042 169.550 1.00 123.36 ?  10  ASP B C   1 
ATOM   1929 O O   . ASP B 2 16  ? 97.039  105.016 168.884 1.00 123.36 ?  10  ASP B O   1 
ATOM   1930 C CB  . ASP B 2 16  ? 99.513  106.617 170.410 1.00 123.36 ?  10  ASP B CB  1 
ATOM   1931 C CG  . ASP B 2 16  ? 99.044  107.007 171.798 1.00 123.36 ?  10  ASP B CG  1 
ATOM   1932 O OD1 . ASP B 2 16  ? 98.239  107.956 171.910 1.00 123.36 ?  10  ASP B OD1 1 
ATOM   1933 O OD2 . ASP B 2 16  ? 99.479  106.365 172.777 1.00 123.36 ?  10  ASP B OD2 1 
ATOM   1934 N N   . GLN B 2 17  ? 96.357  106.449 170.481 1.00 122.97 ?  11  GLN B N   1 
ATOM   1935 C CA  . GLN B 2 17  ? 95.132  105.695 170.724 1.00 122.97 ?  11  GLN B CA  1 
ATOM   1936 C C   . GLN B 2 17  ? 94.233  105.706 169.495 1.00 122.97 ?  11  GLN B C   1 
ATOM   1937 O O   . GLN B 2 17  ? 93.637  104.681 169.143 1.00 122.97 ?  11  GLN B O   1 
ATOM   1938 C CB  . GLN B 2 17  ? 94.399  106.268 171.938 1.00 122.97 ?  11  GLN B CB  1 
ATOM   1939 C CG  . GLN B 2 17  ? 93.332  105.349 172.523 1.00 122.97 ?  11  GLN B CG  1 
ATOM   1940 C CD  . GLN B 2 17  ? 92.061  105.310 171.694 1.00 122.97 ?  11  GLN B CD  1 
ATOM   1941 O OE1 . GLN B 2 17  ? 91.775  106.232 170.930 1.00 122.97 ?  11  GLN B OE1 1 
ATOM   1942 N NE2 . GLN B 2 17  ? 91.292  104.238 171.842 1.00 122.97 ?  11  GLN B NE2 1 
ATOM   1943 N N   . LEU B 2 18  ? 94.124  106.856 168.826 1.00 122.51 ?  12  LEU B N   1 
ATOM   1944 C CA  . LEU B 2 18  ? 93.302  106.931 167.623 1.00 122.51 ?  12  LEU B CA  1 
ATOM   1945 C C   . LEU B 2 18  ? 93.874  106.062 166.510 1.00 122.51 ?  12  LEU B C   1 
ATOM   1946 O O   . LEU B 2 18  ? 93.124  105.391 165.792 1.00 122.51 ?  12  LEU B O   1 
ATOM   1947 C CB  . LEU B 2 18  ? 93.178  108.383 167.161 1.00 122.51 ?  12  LEU B CB  1 
ATOM   1948 C CG  . LEU B 2 18  ? 92.412  109.324 168.095 1.00 122.51 ?  12  LEU B CG  1 
ATOM   1949 C CD1 . LEU B 2 18  ? 92.498  110.757 167.594 1.00 122.51 ?  12  LEU B CD1 1 
ATOM   1950 C CD2 . LEU B 2 18  ? 90.960  108.891 168.229 1.00 122.51 ?  12  LEU B CD2 1 
ATOM   1951 N N   . ARG B 2 19  ? 95.200  106.060 166.349 1.00 121.70 ?  13  ARG B N   1 
ATOM   1952 C CA  . ARG B 2 19  ? 95.814  105.203 165.339 1.00 121.70 ?  13  ARG B CA  1 
ATOM   1953 C C   . ARG B 2 19  ? 95.570  103.731 165.646 1.00 121.70 ?  13  ARG B C   1 
ATOM   1954 O O   . ARG B 2 19  ? 95.265  102.942 164.744 1.00 121.70 ?  13  ARG B O   1 
ATOM   1955 C CB  . ARG B 2 19  ? 97.313  105.491 165.248 1.00 121.70 ?  13  ARG B CB  1 
ATOM   1956 C CG  . ARG B 2 19  ? 97.650  106.829 164.610 1.00 121.70 ?  13  ARG B CG  1 
ATOM   1957 C CD  . ARG B 2 19  ? 99.147  107.093 164.629 1.00 121.70 ?  13  ARG B CD  1 
ATOM   1958 N NE  . ARG B 2 19  ? 99.896  106.067 163.909 1.00 121.70 ?  13  ARG B NE  1 
ATOM   1959 C CZ  . ARG B 2 19  ? 101.220 106.051 163.786 1.00 121.70 ?  13  ARG B CZ  1 
ATOM   1960 N NH1 . ARG B 2 19  ? 101.955 107.009 164.335 1.00 121.70 1  13  ARG B NH1 1 
ATOM   1961 N NH2 . ARG B 2 19  ? 101.811 105.074 163.111 1.00 121.70 ?  13  ARG B NH2 1 
ATOM   1962 N N   . GLN B 2 20  ? 95.704  103.340 166.916 1.00 120.23 ?  14  GLN B N   1 
ATOM   1963 C CA  . GLN B 2 20  ? 95.448  101.952 167.288 1.00 120.23 ?  14  GLN B CA  1 
ATOM   1964 C C   . GLN B 2 20  ? 93.994  101.577 167.034 1.00 120.23 ?  14  GLN B C   1 
ATOM   1965 O O   . GLN B 2 20  ? 93.704  100.477 166.548 1.00 120.23 ?  14  GLN B O   1 
ATOM   1966 C CB  . GLN B 2 20  ? 95.814  101.726 168.755 1.00 120.23 ?  14  GLN B CB  1 
ATOM   1967 C CG  . GLN B 2 20  ? 97.304  101.826 169.047 1.00 120.23 ?  14  GLN B CG  1 
ATOM   1968 C CD  . GLN B 2 20  ? 98.105  100.717 168.392 1.00 120.23 ?  14  GLN B CD  1 
ATOM   1969 O OE1 . GLN B 2 20  ? 97.543  99.779  167.827 1.00 120.23 ?  14  GLN B OE1 1 
ATOM   1970 N NE2 . GLN B 2 20  ? 99.427  100.820 168.464 1.00 120.23 ?  14  GLN B NE2 1 
ATOM   1971 N N   . GLU B 2 21  ? 93.063  102.479 167.352 1.00 117.42 ?  15  GLU B N   1 
ATOM   1972 C CA  . GLU B 2 21  ? 91.652  102.200 167.107 1.00 117.42 ?  15  GLU B CA  1 
ATOM   1973 C C   . GLU B 2 21  ? 91.374  102.064 165.616 1.00 117.42 ?  15  GLU B C   1 
ATOM   1974 O O   . GLU B 2 21  ? 90.609  101.187 165.196 1.00 117.42 ?  15  GLU B O   1 
ATOM   1975 C CB  . GLU B 2 21  ? 90.788  103.304 167.717 1.00 117.42 ?  15  GLU B CB  1 
ATOM   1976 C CG  . GLU B 2 21  ? 89.288  103.073 167.587 1.00 117.42 ?  15  GLU B CG  1 
ATOM   1977 C CD  . GLU B 2 21  ? 88.816  101.843 168.337 1.00 117.42 ?  15  GLU B CD  1 
ATOM   1978 O OE1 . GLU B 2 21  ? 89.600  101.297 169.143 1.00 117.42 ?  15  GLU B OE1 1 
ATOM   1979 O OE2 . GLU B 2 21  ? 87.661  101.421 168.122 1.00 117.42 ?  15  GLU B OE2 1 
ATOM   1980 N N   . ALA B 2 22  ? 91.987  102.922 164.798 1.00 115.45 ?  16  ALA B N   1 
ATOM   1981 C CA  . ALA B 2 22  ? 91.798  102.825 163.355 1.00 115.45 ?  16  ALA B CA  1 
ATOM   1982 C C   . ALA B 2 22  ? 92.356  101.514 162.817 1.00 115.45 ?  16  ALA B C   1 
ATOM   1983 O O   . ALA B 2 22  ? 91.735  100.869 161.964 1.00 115.45 ?  16  ALA B O   1 
ATOM   1984 C CB  . ALA B 2 22  ? 92.458  104.015 162.659 1.00 115.45 ?  16  ALA B CB  1 
ATOM   1985 N N   . GLU B 2 23  ? 93.528  101.102 163.304 1.00 114.89 ?  17  GLU B N   1 
ATOM   1986 C CA  . GLU B 2 23  ? 94.097  99.830  162.871 1.00 114.89 ?  17  GLU B CA  1 
ATOM   1987 C C   . GLU B 2 23  ? 93.208  98.663  163.284 1.00 114.89 ?  17  GLU B C   1 
ATOM   1988 O O   . GLU B 2 23  ? 93.012  97.717  162.511 1.00 114.89 ?  17  GLU B O   1 
ATOM   1989 C CB  . GLU B 2 23  ? 95.504  99.662  163.445 1.00 114.89 ?  17  GLU B CB  1 
ATOM   1990 C CG  . GLU B 2 23  ? 96.528  100.625 162.866 1.00 114.89 ?  17  GLU B CG  1 
ATOM   1991 C CD  . GLU B 2 23  ? 97.903  100.453 163.480 1.00 114.89 ?  17  GLU B CD  1 
ATOM   1992 O OE1 . GLU B 2 23  ? 98.056  99.584  164.364 1.00 114.89 ?  17  GLU B OE1 1 
ATOM   1993 O OE2 . GLU B 2 23  ? 98.831  101.186 163.079 1.00 114.89 ?  17  GLU B OE2 1 
ATOM   1994 N N   . GLN B 2 24  ? 92.660  98.712  164.500 1.00 114.63 ?  18  GLN B N   1 
ATOM   1995 C CA  . GLN B 2 24  ? 91.771  97.645  164.948 1.00 114.63 ?  18  GLN B CA  1 
ATOM   1996 C C   . GLN B 2 24  ? 90.507  97.592  164.101 1.00 114.63 ?  18  GLN B C   1 
ATOM   1997 O O   . GLN B 2 24  ? 90.031  96.507  163.748 1.00 114.63 ?  18  GLN B O   1 
ATOM   1998 C CB  . GLN B 2 24  ? 91.420  97.840  166.424 1.00 114.63 ?  18  GLN B CB  1 
ATOM   1999 C CG  . GLN B 2 24  ? 92.584  97.610  167.375 1.00 114.63 ?  18  GLN B CG  1 
ATOM   2000 C CD  . GLN B 2 24  ? 93.042  96.165  167.402 1.00 114.63 ?  18  GLN B CD  1 
ATOM   2001 O OE1 . GLN B 2 24  ? 92.416  95.292  166.801 1.00 114.63 ?  18  GLN B OE1 1 
ATOM   2002 N NE2 . GLN B 2 24  ? 94.141  95.905  168.100 1.00 114.63 ?  18  GLN B NE2 1 
ATOM   2003 N N   . LEU B 2 25  ? 89.948  98.755  163.759 1.00 111.72 ?  19  LEU B N   1 
ATOM   2004 C CA  . LEU B 2 25  ? 88.762  98.776  162.909 1.00 111.72 ?  19  LEU B CA  1 
ATOM   2005 C C   . LEU B 2 25  ? 89.075  98.244  161.516 1.00 111.72 ?  19  LEU B C   1 
ATOM   2006 O O   . LEU B 2 25  ? 88.263  97.524  160.925 1.00 111.72 ?  19  LEU B O   1 
ATOM   2007 C CB  . LEU B 2 25  ? 88.197  100.194 162.826 1.00 111.72 ?  19  LEU B CB  1 
ATOM   2008 C CG  . LEU B 2 25  ? 87.573  100.754 164.106 1.00 111.72 ?  19  LEU B CG  1 
ATOM   2009 C CD1 . LEU B 2 25  ? 87.101  102.179 163.881 1.00 111.72 ?  19  LEU B CD1 1 
ATOM   2010 C CD2 . LEU B 2 25  ? 86.422  99.881  164.585 1.00 111.72 ?  19  LEU B CD2 1 
ATOM   2011 N N   . LYS B 2 26  ? 90.246  98.586  160.973 1.00 111.89 ?  20  LYS B N   1 
ATOM   2012 C CA  . LYS B 2 26  ? 90.632  98.054  159.670 1.00 111.89 ?  20  LYS B CA  1 
ATOM   2013 C C   . LYS B 2 26  ? 90.780  96.539  159.720 1.00 111.89 ?  20  LYS B C   1 
ATOM   2014 O O   . LYS B 2 26  ? 90.336  95.833  158.807 1.00 111.89 ?  20  LYS B O   1 
ATOM   2015 C CB  . LYS B 2 26  ? 91.932  98.705  159.197 1.00 111.89 ?  20  LYS B CB  1 
ATOM   2016 C CG  . LYS B 2 26  ? 91.770  100.145 158.730 1.00 111.89 ?  20  LYS B CG  1 
ATOM   2017 C CD  . LYS B 2 26  ? 93.023  100.655 158.028 1.00 111.89 ?  20  LYS B CD  1 
ATOM   2018 C CE  . LYS B 2 26  ? 94.187  100.836 158.991 1.00 111.89 ?  20  LYS B CE  1 
ATOM   2019 N NZ  . LYS B 2 26  ? 93.930  101.913 159.985 1.00 111.89 1  20  LYS B NZ  1 
ATOM   2020 N N   . ASN B 2 27  ? 91.399  96.018  160.783 1.00 108.82 ?  21  ASN B N   1 
ATOM   2021 C CA  . ASN B 2 27  ? 91.539  94.571  160.914 1.00 108.82 ?  21  ASN B CA  1 
ATOM   2022 C C   . ASN B 2 27  ? 90.178  93.899  161.051 1.00 108.82 ?  21  ASN B C   1 
ATOM   2023 O O   . ASN B 2 27  ? 89.949  92.822  160.488 1.00 108.82 ?  21  ASN B O   1 
ATOM   2024 C CB  . ASN B 2 27  ? 92.427  94.233  162.111 1.00 108.82 ?  21  ASN B CB  1 
ATOM   2025 C CG  . ASN B 2 27  ? 93.866  94.664  161.910 1.00 108.82 ?  21  ASN B CG  1 
ATOM   2026 O OD1 . ASN B 2 27  ? 94.629  94.009  161.200 1.00 108.82 ?  21  ASN B OD1 1 
ATOM   2027 N ND2 . ASN B 2 27  ? 94.247  95.768  162.541 1.00 108.82 ?  21  ASN B ND2 1 
ATOM   2028 N N   . GLN B 2 28  ? 89.260  94.520  161.794 1.00 105.47 ?  22  GLN B N   1 
ATOM   2029 C CA  . GLN B 2 28  ? 87.922  93.954  161.938 1.00 105.47 ?  22  GLN B CA  1 
ATOM   2030 C C   . GLN B 2 28  ? 87.185  93.942  160.605 1.00 105.47 ?  22  GLN B C   1 
ATOM   2031 O O   . GLN B 2 28  ? 86.507  92.963  160.272 1.00 105.47 ?  22  GLN B O   1 
ATOM   2032 C CB  . GLN B 2 28  ? 87.132  94.743  162.982 1.00 105.47 ?  22  GLN B CB  1 
ATOM   2033 C CG  . GLN B 2 28  ? 85.733  94.206  163.243 1.00 105.47 ?  22  GLN B CG  1 
ATOM   2034 C CD  . GLN B 2 28  ? 84.998  94.989  164.313 1.00 105.47 ?  22  GLN B CD  1 
ATOM   2035 O OE1 . GLN B 2 28  ? 85.542  95.929  164.894 1.00 105.47 ?  22  GLN B OE1 1 
ATOM   2036 N NE2 . GLN B 2 28  ? 83.755  94.605  164.580 1.00 105.47 ?  22  GLN B NE2 1 
ATOM   2037 N N   . ILE B 2 29  ? 87.303  95.022  159.830 1.00 103.29 ?  23  ILE B N   1 
ATOM   2038 C CA  . ILE B 2 29  ? 86.665  95.067  158.518 1.00 103.29 ?  23  ILE B CA  1 
ATOM   2039 C C   . ILE B 2 29  ? 87.260  94.004  157.604 1.00 103.29 ?  23  ILE B C   1 
ATOM   2040 O O   . ILE B 2 29  ? 86.541  93.340  156.848 1.00 103.29 ?  23  ILE B O   1 
ATOM   2041 C CB  . ILE B 2 29  ? 86.794  96.476  157.908 1.00 103.29 ?  23  ILE B CB  1 
ATOM   2042 C CG1 . ILE B 2 29  ? 85.977  97.481  158.726 1.00 103.29 ?  23  ILE B CG1 1 
ATOM   2043 C CG2 . ILE B 2 29  ? 86.340  96.470  156.452 1.00 103.29 ?  23  ILE B CG2 1 
ATOM   2044 C CD1 . ILE B 2 29  ? 86.235  98.929  158.362 1.00 103.29 ?  23  ILE B CD1 1 
ATOM   2045 N N   . ARG B 2 30  ? 88.582  93.825  157.659 1.00 102.87 ?  24  ARG B N   1 
ATOM   2046 C CA  . ARG B 2 30  ? 89.220  92.796  156.844 1.00 102.87 ?  24  ARG B CA  1 
ATOM   2047 C C   . ARG B 2 30  ? 88.733  91.407  157.236 1.00 102.87 ?  24  ARG B C   1 
ATOM   2048 O O   . ARG B 2 30  ? 88.455  90.570  156.369 1.00 102.87 ?  24  ARG B O   1 
ATOM   2049 C CB  . ARG B 2 30  ? 90.740  92.891  156.980 1.00 102.87 ?  24  ARG B CB  1 
ATOM   2050 C CG  . ARG B 2 30  ? 91.509  91.931  156.085 1.00 102.87 ?  24  ARG B CG  1 
ATOM   2051 C CD  . ARG B 2 30  ? 93.009  92.043  156.308 1.00 102.87 ?  24  ARG B CD  1 
ATOM   2052 N NE  . ARG B 2 30  ? 93.508  93.387  156.032 1.00 102.87 ?  24  ARG B NE  1 
ATOM   2053 C CZ  . ARG B 2 30  ? 94.777  93.759  156.172 1.00 102.87 ?  24  ARG B CZ  1 
ATOM   2054 N NH1 . ARG B 2 30  ? 95.689  92.889  156.587 1.00 102.87 1  24  ARG B NH1 1 
ATOM   2055 N NH2 . ARG B 2 30  ? 95.136  95.006  155.897 1.00 102.87 ?  24  ARG B NH2 1 
ATOM   2056 N N   . ASP B 2 31  ? 88.620  91.145  158.540 1.00 100.47 ?  25  ASP B N   1 
ATOM   2057 C CA  . ASP B 2 31  ? 88.141  89.842  158.992 1.00 100.47 ?  25  ASP B CA  1 
ATOM   2058 C C   . ASP B 2 31  ? 86.698  89.609  158.562 1.00 100.47 ?  25  ASP B C   1 
ATOM   2059 O O   . ASP B 2 31  ? 86.339  88.504  158.140 1.00 100.47 ?  25  ASP B O   1 
ATOM   2060 C CB  . ASP B 2 31  ? 88.272  89.736  160.511 1.00 100.47 ?  25  ASP B CB  1 
ATOM   2061 C CG  . ASP B 2 31  ? 89.706  89.869  160.983 1.00 100.47 ?  25  ASP B CG  1 
ATOM   2062 O OD1 . ASP B 2 31  ? 90.621  89.483  160.226 1.00 100.47 ?  25  ASP B OD1 1 
ATOM   2063 O OD2 . ASP B 2 31  ? 89.919  90.360  162.112 1.00 100.47 ?  25  ASP B OD2 1 
ATOM   2064 N N   . ALA B 2 32  ? 85.856  90.640  158.662 1.00 95.15  ?  26  ALA B N   1 
ATOM   2065 C CA  . ALA B 2 32  ? 84.467  90.498  158.238 1.00 95.15  ?  26  ALA B CA  1 
ATOM   2066 C C   . ALA B 2 32  ? 84.373  90.248  156.739 1.00 95.15  ?  26  ALA B C   1 
ATOM   2067 O O   . ALA B 2 32  ? 83.561  89.430  156.289 1.00 95.15  ?  26  ALA B O   1 
ATOM   2068 C CB  . ALA B 2 32  ? 83.671  91.744  158.625 1.00 95.15  ?  26  ALA B CB  1 
ATOM   2069 N N   . ARG B 2 33  ? 85.195  90.942  155.949 1.00 90.12  ?  27  ARG B N   1 
ATOM   2070 C CA  . ARG B 2 33  ? 85.192  90.728  154.506 1.00 90.12  ?  27  ARG B CA  1 
ATOM   2071 C C   . ARG B 2 33  ? 85.707  89.340  154.147 1.00 90.12  ?  27  ARG B C   1 
ATOM   2072 O O   . ARG B 2 33  ? 85.241  88.742  153.170 1.00 90.12  ?  27  ARG B O   1 
ATOM   2073 C CB  . ARG B 2 33  ? 86.036  91.803  153.821 1.00 90.12  ?  27  ARG B CB  1 
ATOM   2074 C CG  . ARG B 2 33  ? 86.029  91.728  152.305 1.00 90.12  ?  27  ARG B CG  1 
ATOM   2075 C CD  . ARG B 2 33  ? 86.834  92.863  151.689 1.00 90.12  ?  27  ARG B CD  1 
ATOM   2076 N NE  . ARG B 2 33  ? 86.268  94.172  152.004 1.00 90.12  ?  27  ARG B NE  1 
ATOM   2077 C CZ  . ARG B 2 33  ? 86.773  95.328  151.584 1.00 90.12  ?  27  ARG B CZ  1 
ATOM   2078 N NH1 . ARG B 2 33  ? 87.861  95.349  150.825 1.00 90.12  1  27  ARG B NH1 1 
ATOM   2079 N NH2 . ARG B 2 33  ? 86.187  96.469  151.923 1.00 90.12  ?  27  ARG B NH2 1 
ATOM   2080 N N   . LYS B 2 34  ? 86.661  88.815  154.918 1.00 92.43  ?  28  LYS B N   1 
ATOM   2081 C CA  . LYS B 2 34  ? 87.165  87.471  154.657 1.00 92.43  ?  28  LYS B CA  1 
ATOM   2082 C C   . LYS B 2 34  ? 86.140  86.414  155.049 1.00 92.43  ?  28  LYS B C   1 
ATOM   2083 O O   . LYS B 2 34  ? 86.038  85.368  154.398 1.00 92.43  ?  28  LYS B O   1 
ATOM   2084 C CB  . LYS B 2 34  ? 88.481  87.254  155.405 1.00 92.43  ?  28  LYS B CB  1 
ATOM   2085 C CG  . LYS B 2 34  ? 89.045  85.843  155.299 1.00 92.43  ?  28  LYS B CG  1 
ATOM   2086 C CD  . LYS B 2 34  ? 88.670  84.993  156.506 1.00 92.43  ?  28  LYS B CD  1 
ATOM   2087 C CE  . LYS B 2 34  ? 89.304  83.613  156.435 1.00 92.43  ?  28  LYS B CE  1 
ATOM   2088 N NZ  . LYS B 2 34  ? 88.857  82.848  155.238 1.00 92.43  1  28  LYS B NZ  1 
ATOM   2089 N N   . ALA B 2 35  ? 85.373  86.668  156.112 1.00 91.42  ?  29  ALA B N   1 
ATOM   2090 C CA  . ALA B 2 35  ? 84.358  85.708  156.532 1.00 91.42  ?  29  ALA B CA  1 
ATOM   2091 C C   . ALA B 2 35  ? 83.275  85.555  155.472 1.00 91.42  ?  29  ALA B C   1 
ATOM   2092 O O   . ALA B 2 35  ? 82.800  84.442  155.215 1.00 91.42  ?  29  ALA B O   1 
ATOM   2093 C CB  . ALA B 2 35  ? 83.747  86.141  157.865 1.00 91.42  ?  29  ALA B CB  1 
ATOM   2094 N N   . CYS B 2 36  ? 82.871  86.660  154.846 1.00 87.32  ?  30  CYS B N   1 
ATOM   2095 C CA  . CYS B 2 36  ? 81.866  86.616  153.792 1.00 87.32  ?  30  CYS B CA  1 
ATOM   2096 C C   . CYS B 2 36  ? 82.412  86.082  152.475 1.00 87.32  ?  30  CYS B C   1 
ATOM   2097 O O   . CYS B 2 36  ? 81.625  85.830  151.556 1.00 87.32  ?  30  CYS B O   1 
ATOM   2098 C CB  . CYS B 2 36  ? 81.278  88.012  153.570 1.00 87.32  ?  30  CYS B CB  1 
ATOM   2099 S SG  . CYS B 2 36  ? 80.418  88.693  155.008 1.00 87.32  ?  30  CYS B SG  1 
ATOM   2100 N N   . ALA B 2 37  ? 83.729  85.904  152.359 1.00 86.28  ?  31  ALA B N   1 
ATOM   2101 C CA  . ALA B 2 37  ? 84.341  85.384  151.136 1.00 86.28  ?  31  ALA B CA  1 
ATOM   2102 C C   . ALA B 2 37  ? 84.211  83.860  151.118 1.00 86.28  ?  31  ALA B C   1 
ATOM   2103 O O   . ALA B 2 37  ? 85.183  83.108  151.223 1.00 86.28  ?  31  ALA B O   1 
ATOM   2104 C CB  . ALA B 2 37  ? 85.795  85.825  151.039 1.00 86.28  ?  31  ALA B CB  1 
ATOM   2105 N N   . ASP B 2 38  ? 82.962  83.407  150.984 1.00 83.82  ?  32  ASP B N   1 
ATOM   2106 C CA  . ASP B 2 38  ? 82.697  81.973  150.954 1.00 83.82  ?  32  ASP B CA  1 
ATOM   2107 C C   . ASP B 2 38  ? 83.432  81.300  149.803 1.00 83.82  ?  32  ASP B C   1 
ATOM   2108 O O   . ASP B 2 38  ? 83.910  80.167  149.938 1.00 83.82  ?  32  ASP B O   1 
ATOM   2109 C CB  . ASP B 2 38  ? 81.192  81.722  150.848 1.00 83.82  ?  32  ASP B CB  1 
ATOM   2110 C CG  . ASP B 2 38  ? 80.849  80.246  150.807 1.00 83.82  ?  32  ASP B CG  1 
ATOM   2111 O OD1 . ASP B 2 38  ? 81.009  79.568  151.844 1.00 83.82  ?  32  ASP B OD1 1 
ATOM   2112 O OD2 . ASP B 2 38  ? 80.419  79.764  149.738 1.00 83.82  ?  32  ASP B OD2 1 
ATOM   2113 N N   . ALA B 2 39  ? 83.534  81.979  148.664 1.00 83.22  ?  33  ALA B N   1 
ATOM   2114 C CA  . ALA B 2 39  ? 84.219  81.436  147.498 1.00 83.22  ?  33  ALA B CA  1 
ATOM   2115 C C   . ALA B 2 39  ? 84.397  82.560  146.488 1.00 83.22  ?  33  ALA B C   1 
ATOM   2116 O O   . ALA B 2 39  ? 83.808  83.637  146.616 1.00 83.22  ?  33  ALA B O   1 
ATOM   2117 C CB  . ALA B 2 39  ? 83.448  80.264  146.886 1.00 83.22  ?  33  ALA B CB  1 
ATOM   2118 N N   . THR B 2 40  ? 85.218  82.294  145.479 1.00 79.89  ?  34  THR B N   1 
ATOM   2119 C CA  . THR B 2 40  ? 85.488  83.261  144.427 1.00 79.89  ?  34  THR B CA  1 
ATOM   2120 C C   . THR B 2 40  ? 84.483  83.108  143.289 1.00 79.89  ?  34  THR B C   1 
ATOM   2121 O O   . THR B 2 40  ? 83.796  82.092  143.163 1.00 79.89  ?  34  THR B O   1 
ATOM   2122 C CB  . THR B 2 40  ? 86.911  83.095  143.890 1.00 79.89  ?  34  THR B CB  1 
ATOM   2123 O OG1 . THR B 2 40  ? 87.077  81.772  143.364 1.00 79.89  ?  34  THR B OG1 1 
ATOM   2124 C CG2 . THR B 2 40  ? 87.932  83.333  144.994 1.00 79.89  ?  34  THR B CG2 1 
ATOM   2125 N N   . LEU B 2 41  ? 84.407  84.145  142.453 1.00 76.69  ?  35  LEU B N   1 
ATOM   2126 C CA  . LEU B 2 41  ? 83.490  84.121  141.320 1.00 76.69  ?  35  LEU B CA  1 
ATOM   2127 C C   . LEU B 2 41  ? 83.833  83.020  140.326 1.00 76.69  ?  35  LEU B C   1 
ATOM   2128 O O   . LEU B 2 41  ? 82.952  82.578  139.579 1.00 76.69  ?  35  LEU B O   1 
ATOM   2129 C CB  . LEU B 2 41  ? 83.499  85.481  140.617 1.00 76.69  ?  35  LEU B CB  1 
ATOM   2130 C CG  . LEU B 2 41  ? 82.564  85.640  139.415 1.00 76.69  ?  35  LEU B CG  1 
ATOM   2131 C CD1 . LEU B 2 41  ? 81.112  85.449  139.826 1.00 76.69  ?  35  LEU B CD1 1 
ATOM   2132 C CD2 . LEU B 2 41  ? 82.764  86.999  138.763 1.00 76.69  ?  35  LEU B CD2 1 
ATOM   2133 N N   . SER B 2 42  ? 85.087  82.566  140.300 1.00 78.76  ?  36  SER B N   1 
ATOM   2134 C CA  . SER B 2 42  ? 85.483  81.532  139.349 1.00 78.76  ?  36  SER B CA  1 
ATOM   2135 C C   . SER B 2 42  ? 84.732  80.231  139.609 1.00 78.76  ?  36  SER B C   1 
ATOM   2136 O O   . SER B 2 42  ? 84.185  79.621  138.683 1.00 78.76  ?  36  SER B O   1 
ATOM   2137 C CB  . SER B 2 42  ? 86.994  81.306  139.425 1.00 78.76  ?  36  SER B CB  1 
ATOM   2138 O OG  . SER B 2 42  ? 87.412  80.326  138.491 1.00 78.76  ?  36  SER B OG  1 
ATOM   2139 N N   . GLN B 2 43  ? 84.694  79.791  140.869 1.00 79.78  ?  37  GLN B N   1 
ATOM   2140 C CA  . GLN B 2 43  ? 84.043  78.527  141.196 1.00 79.78  ?  37  GLN B CA  1 
ATOM   2141 C C   . GLN B 2 43  ? 82.596  78.495  140.721 1.00 79.78  ?  37  GLN B C   1 
ATOM   2142 O O   . GLN B 2 43  ? 82.086  77.430  140.356 1.00 79.78  ?  37  GLN B O   1 
ATOM   2143 C CB  . GLN B 2 43  ? 84.104  78.281  142.704 1.00 79.78  ?  37  GLN B CB  1 
ATOM   2144 C CG  . GLN B 2 43  ? 85.516  78.198  143.262 1.00 79.78  ?  37  GLN B CG  1 
ATOM   2145 C CD  . GLN B 2 43  ? 85.538  77.896  144.748 1.00 79.78  ?  37  GLN B CD  1 
ATOM   2146 O OE1 . GLN B 2 43  ? 84.500  77.634  145.355 1.00 79.78  ?  37  GLN B OE1 1 
ATOM   2147 N NE2 . GLN B 2 43  ? 86.725  77.933  145.341 1.00 79.78  ?  37  GLN B NE2 1 
ATOM   2148 N N   . ILE B 2 44  ? 81.922  79.642  140.717 1.00 79.31  ?  38  ILE B N   1 
ATOM   2149 C CA  . ILE B 2 44  ? 80.522  79.685  140.310 1.00 79.31  ?  38  ILE B CA  1 
ATOM   2150 C C   . ILE B 2 44  ? 80.371  79.946  138.813 1.00 79.31  ?  38  ILE B C   1 
ATOM   2151 O O   . ILE B 2 44  ? 79.361  79.556  138.219 1.00 79.31  ?  38  ILE B O   1 
ATOM   2152 C CB  . ILE B 2 44  ? 79.767  80.744  141.131 1.00 79.31  ?  38  ILE B CB  1 
ATOM   2153 C CG1 . ILE B 2 44  ? 79.776  80.363  142.614 1.00 79.31  ?  38  ILE B CG1 1 
ATOM   2154 C CG2 . ILE B 2 44  ? 78.337  80.894  140.619 1.00 79.31  ?  38  ILE B CG2 1 
ATOM   2155 C CD1 . ILE B 2 44  ? 79.257  81.446  143.533 1.00 79.31  ?  38  ILE B CD1 1 
ATOM   2156 N N   . THR B 2 45  ? 81.353  80.594  138.185 1.00 78.41  ?  39  THR B N   1 
ATOM   2157 C CA  . THR B 2 45  ? 81.301  80.897  136.762 1.00 78.41  ?  39  THR B CA  1 
ATOM   2158 C C   . THR B 2 45  ? 81.976  79.829  135.908 1.00 78.41  ?  39  THR B C   1 
ATOM   2159 O O   . THR B 2 45  ? 82.267  80.081  134.733 1.00 78.41  ?  39  THR B O   1 
ATOM   2160 C CB  . THR B 2 45  ? 81.941  82.261  136.490 1.00 78.41  ?  39  THR B CB  1 
ATOM   2161 O OG1 . THR B 2 45  ? 83.280  82.278  136.999 1.00 78.41  ?  39  THR B OG1 1 
ATOM   2162 C CG2 . THR B 2 45  ? 81.133  83.371  137.149 1.00 78.41  ?  39  THR B CG2 1 
ATOM   2163 N N   . ASN B 2 46  ? 82.232  78.646  136.468 1.00 79.93  ?  40  ASN B N   1 
ATOM   2164 C CA  . ASN B 2 46  ? 82.823  77.553  135.708 1.00 79.93  ?  40  ASN B CA  1 
ATOM   2165 C C   . ASN B 2 46  ? 81.785  76.669  135.033 1.00 79.93  ?  40  ASN B C   1 
ATOM   2166 O O   . ASN B 2 46  ? 82.121  75.968  134.071 1.00 79.93  ?  40  ASN B O   1 
ATOM   2167 C CB  . ASN B 2 46  ? 83.703  76.691  136.619 1.00 79.93  ?  40  ASN B CB  1 
ATOM   2168 C CG  . ASN B 2 46  ? 85.034  77.345  136.935 1.00 79.93  ?  40  ASN B CG  1 
ATOM   2169 O OD1 . ASN B 2 46  ? 85.255  78.514  136.617 1.00 79.93  ?  40  ASN B OD1 1 
ATOM   2170 N ND2 . ASN B 2 46  ? 85.929  76.593  137.563 1.00 79.93  ?  40  ASN B ND2 1 
ATOM   2171 N N   . ASN B 2 47  ? 80.540  76.682  135.508 1.00 80.54  ?  41  ASN B N   1 
ATOM   2172 C CA  . ASN B 2 47  ? 79.486  75.874  134.908 1.00 80.54  ?  41  ASN B CA  1 
ATOM   2173 C C   . ASN B 2 47  ? 78.795  76.577  133.749 1.00 80.54  ?  41  ASN B C   1 
ATOM   2174 O O   . ASN B 2 47  ? 78.266  75.906  132.856 1.00 80.54  ?  41  ASN B O   1 
ATOM   2175 C CB  . ASN B 2 47  ? 78.445  75.495  135.966 1.00 80.54  ?  41  ASN B CB  1 
ATOM   2176 C CG  . ASN B 2 47  ? 77.766  76.706  136.576 1.00 80.54  ?  41  ASN B CG  1 
ATOM   2177 O OD1 . ASN B 2 47  ? 78.222  77.245  137.584 1.00 80.54  ?  41  ASN B OD1 1 
ATOM   2178 N ND2 . ASN B 2 47  ? 76.668  77.140  135.966 1.00 80.54  ?  41  ASN B ND2 1 
ATOM   2179 N N   . ILE B 2 48  ? 78.784  77.912  133.744 1.00 76.65  ?  42  ILE B N   1 
ATOM   2180 C CA  . ILE B 2 48  ? 78.156  78.645  132.653 1.00 76.65  ?  42  ILE B CA  1 
ATOM   2181 C C   . ILE B 2 48  ? 78.841  78.294  131.341 1.00 76.65  ?  42  ILE B C   1 
ATOM   2182 O O   . ILE B 2 48  ? 80.062  78.094  131.284 1.00 76.65  ?  42  ILE B O   1 
ATOM   2183 C CB  . ILE B 2 48  ? 78.209  80.158  132.921 1.00 76.65  ?  42  ILE B CB  1 
ATOM   2184 C CG1 . ILE B 2 48  ? 77.408  80.916  131.860 1.00 76.65  ?  42  ILE B CG1 1 
ATOM   2185 C CG2 . ILE B 2 48  ? 79.651  80.646  132.941 1.00 76.65  ?  42  ILE B CG2 1 
ATOM   2186 C CD1 . ILE B 2 48  ? 77.335  82.410  132.099 1.00 76.65  ?  42  ILE B CD1 1 
ATOM   2187 N N   . ASP B 2 49  ? 78.049  78.215  130.271 1.00 76.14  ?  43  ASP B N   1 
ATOM   2188 C CA  . ASP B 2 49  ? 78.590  77.891  128.963 1.00 76.14  ?  43  ASP B CA  1 
ATOM   2189 C C   . ASP B 2 49  ? 79.604  78.950  128.535 1.00 76.14  ?  43  ASP B C   1 
ATOM   2190 O O   . ASP B 2 49  ? 79.548  80.097  128.985 1.00 76.14  ?  43  ASP B O   1 
ATOM   2191 C CB  . ASP B 2 49  ? 77.466  77.790  127.934 1.00 76.14  ?  43  ASP B CB  1 
ATOM   2192 C CG  . ASP B 2 49  ? 76.665  79.073  127.817 1.00 76.14  ?  43  ASP B CG  1 
ATOM   2193 O OD1 . ASP B 2 49  ? 77.195  80.059  127.262 1.00 76.14  ?  43  ASP B OD1 1 
ATOM   2194 O OD2 . ASP B 2 49  ? 75.506  79.096  128.282 1.00 76.14  ?  43  ASP B OD2 1 
ATOM   2195 N N   . PRO B 2 50  ? 80.543  78.589  127.663 1.00 73.73  ?  44  PRO B N   1 
ATOM   2196 C CA  . PRO B 2 50  ? 81.538  79.568  127.213 1.00 73.73  ?  44  PRO B CA  1 
ATOM   2197 C C   . PRO B 2 50  ? 80.921  80.618  126.304 1.00 73.73  ?  44  PRO B C   1 
ATOM   2198 O O   . PRO B 2 50  ? 79.941  80.369  125.597 1.00 73.73  ?  44  PRO B O   1 
ATOM   2199 C CB  . PRO B 2 50  ? 82.565  78.713  126.463 1.00 73.73  ?  44  PRO B CB  1 
ATOM   2200 C CG  . PRO B 2 50  ? 81.795  77.527  125.999 1.00 73.73  ?  44  PRO B CG  1 
ATOM   2201 C CD  . PRO B 2 50  ? 80.764  77.262  127.060 1.00 73.73  ?  44  PRO B CD  1 
ATOM   2202 N N   . VAL B 2 51  ? 81.516  81.813  126.332 1.00 69.86  ?  45  VAL B N   1 
ATOM   2203 C CA  . VAL B 2 51  ? 81.013  82.914  125.518 1.00 69.86  ?  45  VAL B CA  1 
ATOM   2204 C C   . VAL B 2 51  ? 81.566  82.882  124.099 1.00 69.86  ?  45  VAL B C   1 
ATOM   2205 O O   . VAL B 2 51  ? 80.963  83.473  123.194 1.00 69.86  ?  45  VAL B O   1 
ATOM   2206 C CB  . VAL B 2 51  ? 81.344  84.266  126.174 1.00 69.86  ?  45  VAL B CB  1 
ATOM   2207 C CG1 . VAL B 2 51  ? 82.854  84.456  126.291 1.00 69.86  ?  45  VAL B CG1 1 
ATOM   2208 C CG2 . VAL B 2 51  ? 80.713  85.408  125.390 1.00 69.86  ?  45  VAL B CG2 1 
ATOM   2209 N N   . GLY B 2 52  ? 82.691  82.208  123.875 1.00 69.85  ?  46  GLY B N   1 
ATOM   2210 C CA  . GLY B 2 52  ? 83.292  82.160  122.559 1.00 69.85  ?  46  GLY B CA  1 
ATOM   2211 C C   . GLY B 2 52  ? 84.029  83.440  122.219 1.00 69.85  ?  46  GLY B C   1 
ATOM   2212 O O   . GLY B 2 52  ? 84.167  84.362  123.025 1.00 69.85  ?  46  GLY B O   1 
ATOM   2213 N N   . ARG B 2 53  ? 84.515  83.491  120.981 1.00 68.15  ?  47  ARG B N   1 
ATOM   2214 C CA  . ARG B 2 53  ? 85.254  84.650  120.502 1.00 68.15  ?  47  ARG B CA  1 
ATOM   2215 C C   . ARG B 2 53  ? 84.287  85.709  119.989 1.00 68.15  ?  47  ARG B C   1 
ATOM   2216 O O   . ARG B 2 53  ? 83.388  85.410  119.196 1.00 68.15  ?  47  ARG B O   1 
ATOM   2217 C CB  . ARG B 2 53  ? 86.227  84.242  119.396 1.00 68.15  ?  47  ARG B CB  1 
ATOM   2218 C CG  . ARG B 2 53  ? 87.164  85.357  118.953 1.00 68.15  ?  47  ARG B CG  1 
ATOM   2219 C CD  . ARG B 2 53  ? 87.998  84.943  117.751 1.00 68.15  ?  47  ARG B CD  1 
ATOM   2220 N NE  . ARG B 2 53  ? 87.175  84.714  116.566 1.00 68.15  ?  47  ARG B NE  1 
ATOM   2221 C CZ  . ARG B 2 53  ? 87.658  84.418  115.363 1.00 68.15  ?  47  ARG B CZ  1 
ATOM   2222 N NH1 . ARG B 2 53  ? 88.967  84.315  115.173 1.00 68.15  1  47  ARG B NH1 1 
ATOM   2223 N NH2 . ARG B 2 53  ? 86.830  84.227  114.345 1.00 68.15  ?  47  ARG B NH2 1 
ATOM   2224 N N   . ILE B 2 54  ? 84.474  86.948  120.442 1.00 65.60  ?  48  ILE B N   1 
ATOM   2225 C CA  . ILE B 2 54  ? 83.661  88.071  119.989 1.00 65.60  ?  48  ILE B CA  1 
ATOM   2226 C C   . ILE B 2 54  ? 84.507  88.939  119.068 1.00 65.60  ?  48  ILE B C   1 
ATOM   2227 O O   . ILE B 2 54  ? 85.225  89.835  119.526 1.00 65.60  ?  48  ILE B O   1 
ATOM   2228 C CB  . ILE B 2 54  ? 83.119  88.888  121.176 1.00 65.60  ?  48  ILE B CB  1 
ATOM   2229 C CG1 . ILE B 2 54  ? 82.327  87.990  122.134 1.00 65.60  ?  48  ILE B CG1 1 
ATOM   2230 C CG2 . ILE B 2 54  ? 82.251  90.036  120.680 1.00 65.60  ?  48  ILE B CG2 1 
ATOM   2231 C CD1 . ILE B 2 54  ? 81.126  87.308  121.504 1.00 65.60  ?  48  ILE B CD1 1 
ATOM   2232 N N   . GLN B 2 55  ? 84.427  88.680  117.765 1.00 64.82  ?  49  GLN B N   1 
ATOM   2233 C CA  . GLN B 2 55  ? 85.214  89.408  116.771 1.00 64.82  ?  49  GLN B CA  1 
ATOM   2234 C C   . GLN B 2 55  ? 84.388  90.594  116.290 1.00 64.82  ?  49  GLN B C   1 
ATOM   2235 O O   . GLN B 2 55  ? 83.505  90.449  115.441 1.00 64.82  ?  49  GLN B O   1 
ATOM   2236 C CB  . GLN B 2 55  ? 85.607  88.489  115.619 1.00 64.82  ?  49  GLN B CB  1 
ATOM   2237 C CG  . GLN B 2 55  ? 86.775  88.995  114.782 1.00 64.82  ?  49  GLN B CG  1 
ATOM   2238 C CD  . GLN B 2 55  ? 86.406  90.168  113.894 1.00 64.82  ?  49  GLN B CD  1 
ATOM   2239 O OE1 . GLN B 2 55  ? 85.250  90.325  113.500 1.00 64.82  ?  49  GLN B OE1 1 
ATOM   2240 N NE2 . GLN B 2 55  ? 87.390  91.000  113.575 1.00 64.82  ?  49  GLN B NE2 1 
ATOM   2241 N N   . MET B 2 56  ? 84.671  91.772  116.839 1.00 62.66  ?  50  MET B N   1 
ATOM   2242 C CA  . MET B 2 56  ? 83.979  92.994  116.454 1.00 62.66  ?  50  MET B CA  1 
ATOM   2243 C C   . MET B 2 56  ? 84.716  93.654  115.296 1.00 62.66  ?  50  MET B C   1 
ATOM   2244 O O   . MET B 2 56  ? 85.946  93.771  115.320 1.00 62.66  ?  50  MET B O   1 
ATOM   2245 C CB  . MET B 2 56  ? 83.886  93.956  117.638 1.00 62.66  ?  50  MET B CB  1 
ATOM   2246 C CG  . MET B 2 56  ? 83.147  93.389  118.838 1.00 62.66  ?  50  MET B CG  1 
ATOM   2247 S SD  . MET B 2 56  ? 83.046  94.555  120.210 1.00 62.66  ?  50  MET B SD  1 
ATOM   2248 C CE  . MET B 2 56  ? 82.149  93.582  121.416 1.00 62.66  ?  50  MET B CE  1 
ATOM   2249 N N   . ARG B 2 57  ? 83.963  94.081  114.287 1.00 62.75  ?  51  ARG B N   1 
ATOM   2250 C CA  . ARG B 2 57  ? 84.514  94.748  113.118 1.00 62.75  ?  51  ARG B CA  1 
ATOM   2251 C C   . ARG B 2 57  ? 84.184  96.234  113.164 1.00 62.75  ?  51  ARG B C   1 
ATOM   2252 O O   . ARG B 2 57  ? 83.175  96.647  113.743 1.00 62.75  ?  51  ARG B O   1 
ATOM   2253 C CB  . ARG B 2 57  ? 83.968  94.135  111.825 1.00 62.75  ?  51  ARG B CB  1 
ATOM   2254 C CG  . ARG B 2 57  ? 84.312  92.665  111.643 1.00 62.75  ?  51  ARG B CG  1 
ATOM   2255 C CD  . ARG B 2 57  ? 83.793  92.130  110.318 1.00 62.75  ?  51  ARG B CD  1 
ATOM   2256 N NE  . ARG B 2 57  ? 84.391  92.816  109.176 1.00 62.75  ?  51  ARG B NE  1 
ATOM   2257 C CZ  . ARG B 2 57  ? 84.126  92.529  107.905 1.00 62.75  ?  51  ARG B CZ  1 
ATOM   2258 N NH1 . ARG B 2 57  ? 84.720  93.209  106.934 1.00 62.75  1  51  ARG B NH1 1 
ATOM   2259 N NH2 . ARG B 2 57  ? 83.268  91.563  107.601 1.00 62.75  ?  51  ARG B NH2 1 
ATOM   2260 N N   . THR B 2 58  ? 85.049  97.034  112.544 1.00 59.46  ?  52  THR B N   1 
ATOM   2261 C CA  . THR B 2 58  ? 84.876  98.481  112.524 1.00 59.46  ?  52  THR B CA  1 
ATOM   2262 C C   . THR B 2 58  ? 83.803  98.852  111.508 1.00 59.46  ?  52  THR B C   1 
ATOM   2263 O O   . THR B 2 58  ? 83.960  98.599  110.308 1.00 59.46  ?  52  THR B O   1 
ATOM   2264 C CB  . THR B 2 58  ? 86.196  99.172  112.185 1.00 59.46  ?  52  THR B CB  1 
ATOM   2265 O OG1 . THR B 2 58  ? 87.194  98.802  113.144 1.00 59.46  ?  52  THR B OG1 1 
ATOM   2266 C CG2 . THR B 2 58  ? 86.027  100.686 112.192 1.00 59.46  ?  52  THR B CG2 1 
ATOM   2267 N N   . ARG B 2 59  ? 82.714  99.452  111.988 1.00 60.71  ?  53  ARG B N   1 
ATOM   2268 C CA  . ARG B 2 59  ? 81.632  99.880  111.112 1.00 60.71  ?  53  ARG B CA  1 
ATOM   2269 C C   . ARG B 2 59  ? 81.766  101.334 110.685 1.00 60.71  ?  53  ARG B C   1 
ATOM   2270 O O   . ARG B 2 59  ? 81.334  101.689 109.582 1.00 60.71  ?  53  ARG B O   1 
ATOM   2271 C CB  . ARG B 2 59  ? 80.281  99.680  111.807 1.00 60.71  ?  53  ARG B CB  1 
ATOM   2272 C CG  . ARG B 2 59  ? 80.048  98.270  112.329 1.00 60.71  ?  53  ARG B CG  1 
ATOM   2273 C CD  . ARG B 2 59  ? 80.096  97.236  111.215 1.00 60.71  ?  53  ARG B CD  1 
ATOM   2274 N NE  . ARG B 2 59  ? 79.826  95.887  111.707 1.00 60.71  ?  53  ARG B NE  1 
ATOM   2275 C CZ  . ARG B 2 59  ? 79.832  94.796  110.947 1.00 60.71  ?  53  ARG B CZ  1 
ATOM   2276 N NH1 . ARG B 2 59  ? 80.096  94.884  109.650 1.00 60.71  1  53  ARG B NH1 1 
ATOM   2277 N NH2 . ARG B 2 59  ? 79.574  93.612  111.486 1.00 60.71  ?  53  ARG B NH2 1 
ATOM   2278 N N   . ARG B 2 60  ? 82.356  102.180 111.527 1.00 58.34  ?  54  ARG B N   1 
ATOM   2279 C CA  . ARG B 2 60  ? 82.528  103.594 111.234 1.00 58.34  ?  54  ARG B CA  1 
ATOM   2280 C C   . ARG B 2 60  ? 83.963  104.003 111.531 1.00 58.34  ?  54  ARG B C   1 
ATOM   2281 O O   . ARG B 2 60  ? 84.644  103.387 112.356 1.00 58.34  ?  54  ARG B O   1 
ATOM   2282 C CB  . ARG B 2 60  ? 81.564  104.462 112.056 1.00 58.34  ?  54  ARG B CB  1 
ATOM   2283 C CG  . ARG B 2 60  ? 80.099  104.078 111.918 1.00 58.34  ?  54  ARG B CG  1 
ATOM   2284 C CD  . ARG B 2 60  ? 79.581  104.335 110.513 1.00 58.34  ?  54  ARG B CD  1 
ATOM   2285 N NE  . ARG B 2 60  ? 78.140  104.119 110.411 1.00 58.34  ?  54  ARG B NE  1 
ATOM   2286 C CZ  . ARG B 2 60  ? 77.567  102.940 110.183 1.00 58.34  ?  54  ARG B CZ  1 
ATOM   2287 N NH1 . ARG B 2 60  ? 78.306  101.849 110.032 1.00 58.34  1  54  ARG B NH1 1 
ATOM   2288 N NH2 . ARG B 2 60  ? 76.246  102.852 110.109 1.00 58.34  ?  54  ARG B NH2 1 
ATOM   2289 N N   . THR B 2 61  ? 84.416  105.052 110.848 1.00 58.58  ?  55  THR B N   1 
ATOM   2290 C CA  . THR B 2 61  ? 85.761  105.586 111.034 1.00 58.58  ?  55  THR B CA  1 
ATOM   2291 C C   . THR B 2 61  ? 85.679  107.104 111.026 1.00 58.58  ?  55  THR B C   1 
ATOM   2292 O O   . THR B 2 61  ? 85.300  107.700 110.014 1.00 58.58  ?  55  THR B O   1 
ATOM   2293 C CB  . THR B 2 61  ? 86.713  105.094 109.938 1.00 58.58  ?  55  THR B CB  1 
ATOM   2294 O OG1 . THR B 2 61  ? 86.722  103.661 109.917 1.00 58.58  ?  55  THR B OG1 1 
ATOM   2295 C CG2 . THR B 2 61  ? 88.126  105.603 110.187 1.00 58.58  ?  55  THR B CG2 1 
ATOM   2296 N N   . LEU B 2 62  ? 86.034  107.723 112.149 1.00 57.27  ?  56  LEU B N   1 
ATOM   2297 C CA  . LEU B 2 62  ? 85.977  109.170 112.302 1.00 57.27  ?  56  LEU B CA  1 
ATOM   2298 C C   . LEU B 2 62  ? 87.358  109.762 112.054 1.00 57.27  ?  56  LEU B C   1 
ATOM   2299 O O   . LEU B 2 62  ? 88.355  109.270 112.592 1.00 57.27  ?  56  LEU B O   1 
ATOM   2300 C CB  . LEU B 2 62  ? 85.479  109.548 113.698 1.00 57.27  ?  56  LEU B CB  1 
ATOM   2301 C CG  . LEU B 2 62  ? 84.262  108.765 114.198 1.00 57.27  ?  56  LEU B CG  1 
ATOM   2302 C CD1 . LEU B 2 62  ? 83.717  109.373 115.482 1.00 57.27  ?  56  LEU B CD1 1 
ATOM   2303 C CD2 . LEU B 2 62  ? 83.177  108.699 113.133 1.00 57.27  ?  56  LEU B CD2 1 
ATOM   2304 N N   . ARG B 2 63  ? 87.410  110.819 111.240 1.00 58.99  ?  57  ARG B N   1 
ATOM   2305 C CA  . ARG B 2 63  ? 88.662  111.476 110.881 1.00 58.99  ?  57  ARG B CA  1 
ATOM   2306 C C   . ARG B 2 63  ? 88.558  112.987 111.053 1.00 58.99  ?  57  ARG B C   1 
ATOM   2307 O O   . ARG B 2 63  ? 89.141  113.747 110.276 1.00 58.99  ?  57  ARG B O   1 
ATOM   2308 C CB  . ARG B 2 63  ? 89.063  111.134 109.445 1.00 58.99  ?  57  ARG B CB  1 
ATOM   2309 C CG  . ARG B 2 63  ? 89.212  109.645 109.170 1.00 58.99  ?  57  ARG B CG  1 
ATOM   2310 C CD  . ARG B 2 63  ? 90.369  109.042 109.951 1.00 58.99  ?  57  ARG B CD  1 
ATOM   2311 N NE  . ARG B 2 63  ? 90.572  107.632 109.628 1.00 58.99  ?  57  ARG B NE  1 
ATOM   2312 C CZ  . ARG B 2 63  ? 91.257  107.193 108.576 1.00 58.99  ?  57  ARG B CZ  1 
ATOM   2313 N NH1 . ARG B 2 63  ? 91.386  105.889 108.369 1.00 58.99  1  57  ARG B NH1 1 
ATOM   2314 N NH2 . ARG B 2 63  ? 91.811  108.049 107.727 1.00 58.99  ?  57  ARG B NH2 1 
ATOM   2315 N N   . GLY B 2 64  ? 87.822  113.436 112.067 1.00 58.19  ?  58  GLY B N   1 
ATOM   2316 C CA  . GLY B 2 64  ? 87.617  114.855 112.283 1.00 58.19  ?  58  GLY B CA  1 
ATOM   2317 C C   . GLY B 2 64  ? 88.480  115.433 113.384 1.00 58.19  ?  58  GLY B C   1 
ATOM   2318 O O   . GLY B 2 64  ? 88.882  116.599 113.317 1.00 58.19  ?  58  GLY B O   1 
ATOM   2319 N N   . HIS B 2 65  ? 88.769  114.633 114.407 1.00 58.88  ?  59  HIS B N   1 
ATOM   2320 C CA  . HIS B 2 65  ? 89.559  115.117 115.529 1.00 58.88  ?  59  HIS B CA  1 
ATOM   2321 C C   . HIS B 2 65  ? 90.943  115.557 115.065 1.00 58.88  ?  59  HIS B C   1 
ATOM   2322 O O   . HIS B 2 65  ? 91.521  114.993 114.131 1.00 58.88  ?  59  HIS B O   1 
ATOM   2323 C CB  . HIS B 2 65  ? 89.686  114.032 116.598 1.00 58.88  ?  59  HIS B CB  1 
ATOM   2324 C CG  . HIS B 2 65  ? 88.426  113.798 117.372 1.00 58.88  ?  59  HIS B CG  1 
ATOM   2325 N ND1 . HIS B 2 65  ? 88.118  114.498 118.518 1.00 58.88  ?  59  HIS B ND1 1 
ATOM   2326 C CD2 . HIS B 2 65  ? 87.396  112.945 117.163 1.00 58.88  ?  59  HIS B CD2 1 
ATOM   2327 C CE1 . HIS B 2 65  ? 86.953  114.086 118.983 1.00 58.88  ?  59  HIS B CE1 1 
ATOM   2328 N NE2 . HIS B 2 65  ? 86.493  113.143 118.180 1.00 58.88  ?  59  HIS B NE2 1 
ATOM   2329 N N   . LEU B 2 66  ? 91.473  116.581 115.733 1.00 59.69  ?  60  LEU B N   1 
ATOM   2330 C CA  . LEU B 2 66  ? 92.783  117.137 115.416 1.00 59.69  ?  60  LEU B CA  1 
ATOM   2331 C C   . LEU B 2 66  ? 93.872  116.620 116.347 1.00 59.69  ?  60  LEU B C   1 
ATOM   2332 O O   . LEU B 2 66  ? 94.925  116.174 115.882 1.00 59.69  ?  60  LEU B O   1 
ATOM   2333 C CB  . LEU B 2 66  ? 92.730  118.668 115.483 1.00 59.69  ?  60  LEU B CB  1 
ATOM   2334 C CG  . LEU B 2 66  ? 91.551  119.325 114.763 1.00 59.69  ?  60  LEU B CG  1 
ATOM   2335 C CD1 . LEU B 2 66  ? 91.714  120.837 114.730 1.00 59.69  ?  60  LEU B CD1 1 
ATOM   2336 C CD2 . LEU B 2 66  ? 91.402  118.764 113.359 1.00 59.69  ?  60  LEU B CD2 1 
ATOM   2337 N N   . ALA B 2 67  ? 93.638  116.672 117.654 1.00 59.21  ?  61  ALA B N   1 
ATOM   2338 C CA  . ALA B 2 67  ? 94.595  116.236 118.656 1.00 59.21  ?  61  ALA B CA  1 
ATOM   2339 C C   . ALA B 2 67  ? 94.137  114.915 119.270 1.00 59.21  ?  61  ALA B C   1 
ATOM   2340 O O   . ALA B 2 67  ? 93.138  114.318 118.851 1.00 59.21  ?  61  ALA B O   1 
ATOM   2341 C CB  . ALA B 2 67  ? 94.775  117.324 119.716 1.00 59.21  ?  61  ALA B CB  1 
ATOM   2342 N N   . LYS B 2 68  ? 94.880  114.456 120.274 1.00 60.81  ?  62  LYS B N   1 
ATOM   2343 C CA  . LYS B 2 68  ? 94.578  113.184 120.915 1.00 60.81  ?  62  LYS B CA  1 
ATOM   2344 C C   . LYS B 2 68  ? 93.193  113.217 121.550 1.00 60.81  ?  62  LYS B C   1 
ATOM   2345 O O   . LYS B 2 68  ? 92.871  114.123 122.323 1.00 60.81  ?  62  LYS B O   1 
ATOM   2346 C CB  . LYS B 2 68  ? 95.636  112.873 121.974 1.00 60.81  ?  62  LYS B CB  1 
ATOM   2347 C CG  . LYS B 2 68  ? 97.056  112.793 121.428 1.00 60.81  ?  62  LYS B CG  1 
ATOM   2348 C CD  . LYS B 2 68  ? 98.095  112.814 122.540 1.00 60.81  ?  62  LYS B CD  1 
ATOM   2349 C CE  . LYS B 2 68  ? 98.220  114.197 123.163 1.00 60.81  ?  62  LYS B CE  1 
ATOM   2350 N NZ  . LYS B 2 68  ? 99.302  114.260 124.182 1.00 60.81  1  62  LYS B NZ  1 
ATOM   2351 N N   . ILE B 2 69  ? 92.372  112.223 121.216 1.00 60.02  ?  63  ILE B N   1 
ATOM   2352 C CA  . ILE B 2 69  ? 91.059  112.088 121.837 1.00 60.02  ?  63  ILE B CA  1 
ATOM   2353 C C   . ILE B 2 69  ? 91.253  111.604 123.267 1.00 60.02  ?  63  ILE B C   1 
ATOM   2354 O O   . ILE B 2 69  ? 91.892  110.573 123.507 1.00 60.02  ?  63  ILE B O   1 
ATOM   2355 C CB  . ILE B 2 69  ? 90.169  111.128 121.037 1.00 60.02  ?  63  ILE B CB  1 
ATOM   2356 C CG1 . ILE B 2 69  ? 90.052  111.602 119.585 1.00 60.02  ?  63  ILE B CG1 1 
ATOM   2357 C CG2 . ILE B 2 69  ? 88.787  111.024 121.678 1.00 60.02  ?  63  ILE B CG2 1 
ATOM   2358 C CD1 . ILE B 2 69  ? 89.264  110.667 118.693 1.00 60.02  ?  63  ILE B CD1 1 
ATOM   2359 N N   . TYR B 2 70  ? 90.699  112.347 124.227 1.00 61.88  ?  64  TYR B N   1 
ATOM   2360 C CA  . TYR B 2 70  ? 90.932  112.075 125.641 1.00 61.88  ?  64  TYR B CA  1 
ATOM   2361 C C   . TYR B 2 70  ? 89.646  111.909 126.441 1.00 61.88  ?  64  TYR B C   1 
ATOM   2362 O O   . TYR B 2 70  ? 89.700  111.898 127.677 1.00 61.88  ?  64  TYR B O   1 
ATOM   2363 C CB  . TYR B 2 70  ? 91.783  113.189 126.257 1.00 61.88  ?  64  TYR B CB  1 
ATOM   2364 C CG  . TYR B 2 70  ? 92.884  112.680 127.161 1.00 61.88  ?  64  TYR B CG  1 
ATOM   2365 C CD1 . TYR B 2 70  ? 92.638  112.395 128.497 1.00 61.88  ?  64  TYR B CD1 1 
ATOM   2366 C CD2 . TYR B 2 70  ? 94.169  112.482 126.675 1.00 61.88  ?  64  TYR B CD2 1 
ATOM   2367 C CE1 . TYR B 2 70  ? 93.642  111.928 129.324 1.00 61.88  ?  64  TYR B CE1 1 
ATOM   2368 C CE2 . TYR B 2 70  ? 95.179  112.016 127.494 1.00 61.88  ?  64  TYR B CE2 1 
ATOM   2369 C CZ  . TYR B 2 70  ? 94.910  111.741 128.818 1.00 61.88  ?  64  TYR B CZ  1 
ATOM   2370 O OH  . TYR B 2 70  ? 95.914  111.277 129.637 1.00 61.88  ?  64  TYR B OH  1 
ATOM   2371 N N   . ALA B 2 71  ? 88.496  111.777 125.785 1.00 60.28  ?  65  ALA B N   1 
ATOM   2372 C CA  . ALA B 2 71  ? 87.243  111.583 126.501 1.00 60.28  ?  65  ALA B CA  1 
ATOM   2373 C C   . ALA B 2 71  ? 86.157  111.212 125.503 1.00 60.28  ?  65  ALA B C   1 
ATOM   2374 O O   . ALA B 2 71  ? 86.288  111.448 124.298 1.00 60.28  ?  65  ALA B O   1 
ATOM   2375 C CB  . ALA B 2 71  ? 86.843  112.835 127.289 1.00 60.28  ?  65  ALA B CB  1 
ATOM   2376 N N   . MET B 2 72  ? 85.082  110.629 126.025 1.00 60.08  ?  66  MET B N   1 
ATOM   2377 C CA  . MET B 2 72  ? 83.938  110.223 125.217 1.00 60.08  ?  66  MET B CA  1 
ATOM   2378 C C   . MET B 2 72  ? 82.825  109.800 126.164 1.00 60.08  ?  66  MET B C   1 
ATOM   2379 O O   . MET B 2 72  ? 83.051  109.571 127.355 1.00 60.08  ?  66  MET B O   1 
ATOM   2380 C CB  . MET B 2 72  ? 84.303  109.091 124.252 1.00 60.08  ?  66  MET B CB  1 
ATOM   2381 C CG  . MET B 2 72  ? 84.720  107.794 124.936 1.00 60.08  ?  66  MET B CG  1 
ATOM   2382 S SD  . MET B 2 72  ? 83.336  106.748 125.435 1.00 60.08  ?  66  MET B SD  1 
ATOM   2383 C CE  . MET B 2 72  ? 82.731  106.199 123.842 1.00 60.08  ?  66  MET B CE  1 
ATOM   2384 N N   . HIS B 2 73  ? 81.617  109.695 125.618 1.00 57.93  ?  67  HIS B N   1 
ATOM   2385 C CA  . HIS B 2 73  ? 80.455  109.285 126.396 1.00 57.93  ?  67  HIS B CA  1 
ATOM   2386 C C   . HIS B 2 73  ? 79.283  109.093 125.447 1.00 57.93  ?  67  HIS B C   1 
ATOM   2387 O O   . HIS B 2 73  ? 79.257  109.648 124.345 1.00 57.93  ?  67  HIS B O   1 
ATOM   2388 C CB  . HIS B 2 73  ? 80.110  110.314 127.479 1.00 57.93  ?  67  HIS B CB  1 
ATOM   2389 C CG  . HIS B 2 73  ? 79.061  109.851 128.441 1.00 57.93  ?  67  HIS B CG  1 
ATOM   2390 N ND1 . HIS B 2 73  ? 77.735  110.211 128.327 1.00 57.93  ?  67  HIS B ND1 1 
ATOM   2391 C CD2 . HIS B 2 73  ? 79.142  109.055 129.534 1.00 57.93  ?  67  HIS B CD2 1 
ATOM   2392 C CE1 . HIS B 2 73  ? 77.045  109.658 129.309 1.00 57.93  ?  67  HIS B CE1 1 
ATOM   2393 N NE2 . HIS B 2 73  ? 77.875  108.951 130.055 1.00 57.93  ?  67  HIS B NE2 1 
ATOM   2394 N N   . TRP B 2 74  ? 78.315  108.294 125.889 1.00 57.99  ?  68  TRP B N   1 
ATOM   2395 C CA  . TRP B 2 74  ? 77.097  108.026 125.134 1.00 57.99  ?  68  TRP B CA  1 
ATOM   2396 C C   . TRP B 2 74  ? 75.913  108.630 125.877 1.00 57.99  ?  68  TRP B C   1 
ATOM   2397 O O   . TRP B 2 74  ? 75.670  108.296 127.041 1.00 57.99  ?  68  TRP B O   1 
ATOM   2398 C CB  . TRP B 2 74  ? 76.894  106.524 124.934 1.00 57.99  ?  68  TRP B CB  1 
ATOM   2399 C CG  . TRP B 2 74  ? 77.814  105.924 123.918 1.00 57.99  ?  68  TRP B CG  1 
ATOM   2400 C CD1 . TRP B 2 74  ? 78.975  105.250 124.160 1.00 57.99  ?  68  TRP B CD1 1 
ATOM   2401 C CD2 . TRP B 2 74  ? 77.649  105.942 122.496 1.00 57.99  ?  68  TRP B CD2 1 
ATOM   2402 N NE1 . TRP B 2 74  ? 79.543  104.847 122.975 1.00 57.99  ?  68  TRP B NE1 1 
ATOM   2403 C CE2 . TRP B 2 74  ? 78.748  105.260 121.939 1.00 57.99  ?  68  TRP B CE2 1 
ATOM   2404 C CE3 . TRP B 2 74  ? 76.677  106.470 121.639 1.00 57.99  ?  68  TRP B CE3 1 
ATOM   2405 C CZ2 . TRP B 2 74  ? 78.903  105.092 120.564 1.00 57.99  ?  68  TRP B CZ2 1 
ATOM   2406 C CZ3 . TRP B 2 74  ? 76.834  106.301 120.275 1.00 57.99  ?  68  TRP B CZ3 1 
ATOM   2407 C CH2 . TRP B 2 74  ? 77.938  105.618 119.751 1.00 57.99  ?  68  TRP B CH2 1 
ATOM   2408 N N   . GLY B 2 75  ? 75.181  109.511 125.203 1.00 58.60  ?  69  GLY B N   1 
ATOM   2409 C CA  . GLY B 2 75  ? 74.006  110.128 125.777 1.00 58.60  ?  69  GLY B CA  1 
ATOM   2410 C C   . GLY B 2 75  ? 72.803  109.204 125.735 1.00 58.60  ?  69  GLY B C   1 
ATOM   2411 O O   . GLY B 2 75  ? 72.888  108.024 125.392 1.00 58.60  ?  69  GLY B O   1 
ATOM   2412 N N   . THR B 2 76  ? 71.650  109.771 126.099 1.00 60.47  ?  70  THR B N   1 
ATOM   2413 C CA  . THR B 2 76  ? 70.414  108.996 126.092 1.00 60.47  ?  70  THR B CA  1 
ATOM   2414 C C   . THR B 2 76  ? 70.136  108.397 124.720 1.00 60.47  ?  70  THR B C   1 
ATOM   2415 O O   . THR B 2 76  ? 69.592  107.291 124.624 1.00 60.47  ?  70  THR B O   1 
ATOM   2416 C CB  . THR B 2 76  ? 69.239  109.870 126.534 1.00 60.47  ?  70  THR B CB  1 
ATOM   2417 O OG1 . THR B 2 76  ? 68.036  109.090 126.548 1.00 60.47  ?  70  THR B OG1 1 
ATOM   2418 C CG2 . THR B 2 76  ? 69.059  111.060 125.594 1.00 60.47  ?  70  THR B CG2 1 
ATOM   2419 N N   . ASP B 2 77  ? 70.499  109.105 123.654 1.00 60.55  ?  71  ASP B N   1 
ATOM   2420 C CA  . ASP B 2 77  ? 70.320  108.613 122.294 1.00 60.55  ?  71  ASP B CA  1 
ATOM   2421 C C   . ASP B 2 77  ? 71.595  107.909 121.846 1.00 60.55  ?  71  ASP B C   1 
ATOM   2422 O O   . ASP B 2 77  ? 72.686  108.487 121.909 1.00 60.55  ?  71  ASP B O   1 
ATOM   2423 C CB  . ASP B 2 77  ? 69.969  109.758 121.343 1.00 60.55  ?  71  ASP B CB  1 
ATOM   2424 C CG  . ASP B 2 77  ? 70.957  110.907 121.419 1.00 60.55  ?  71  ASP B CG  1 
ATOM   2425 O OD1 . ASP B 2 77  ? 71.837  110.882 122.305 1.00 60.55  ?  71  ASP B OD1 1 
ATOM   2426 O OD2 . ASP B 2 77  ? 70.852  111.837 120.592 1.00 60.55  ?  71  ASP B OD2 1 
ATOM   2427 N N   . SER B 2 78  ? 71.457  106.662 121.396 1.00 59.30  ?  72  SER B N   1 
ATOM   2428 C CA  . SER B 2 78  ? 72.606  105.872 120.969 1.00 59.30  ?  72  SER B CA  1 
ATOM   2429 C C   . SER B 2 78  ? 73.144  106.289 119.607 1.00 59.30  ?  72  SER B C   1 
ATOM   2430 O O   . SER B 2 78  ? 74.052  105.622 119.096 1.00 59.30  ?  72  SER B O   1 
ATOM   2431 C CB  . SER B 2 78  ? 72.233  104.389 120.940 1.00 59.30  ?  72  SER B CB  1 
ATOM   2432 O OG  . SER B 2 78  ? 71.166  104.149 120.039 1.00 59.30  ?  72  SER B OG  1 
ATOM   2433 N N   . ARG B 2 79  ? 72.621  107.358 119.008 1.00 57.07  ?  73  ARG B N   1 
ATOM   2434 C CA  . ARG B 2 79  ? 73.074  107.809 117.699 1.00 57.07  ?  73  ARG B CA  1 
ATOM   2435 C C   . ARG B 2 79  ? 74.112  108.918 117.771 1.00 57.07  ?  73  ARG B C   1 
ATOM   2436 O O   . ARG B 2 79  ? 75.000  108.974 116.914 1.00 57.07  ?  73  ARG B O   1 
ATOM   2437 C CB  . ARG B 2 79  ? 71.881  108.294 116.867 1.00 57.07  ?  73  ARG B CB  1 
ATOM   2438 C CG  . ARG B 2 79  ? 72.240  108.689 115.444 1.00 57.07  ?  73  ARG B CG  1 
ATOM   2439 C CD  . ARG B 2 79  ? 71.003  109.026 114.631 1.00 57.07  ?  73  ARG B CD  1 
ATOM   2440 N NE  . ARG B 2 79  ? 71.332  109.363 113.248 1.00 57.07  ?  73  ARG B NE  1 
ATOM   2441 C CZ  . ARG B 2 79  ? 70.436  109.702 112.326 1.00 57.07  ?  73  ARG B CZ  1 
ATOM   2442 N NH1 . ARG B 2 79  ? 69.146  109.751 112.630 1.00 57.07  1  73  ARG B NH1 1 
ATOM   2443 N NH2 . ARG B 2 79  ? 70.832  109.992 111.094 1.00 57.07  ?  73  ARG B NH2 1 
ATOM   2444 N N   . LEU B 2 80  ? 74.027  109.797 118.765 1.00 57.01  ?  74  LEU B N   1 
ATOM   2445 C CA  . LEU B 2 80  ? 74.980  110.885 118.934 1.00 57.01  ?  74  LEU B CA  1 
ATOM   2446 C C   . LEU B 2 80  ? 76.106  110.445 119.860 1.00 57.01  ?  74  LEU B C   1 
ATOM   2447 O O   . LEU B 2 80  ? 75.868  109.774 120.869 1.00 57.01  ?  74  LEU B O   1 
ATOM   2448 C CB  . LEU B 2 80  ? 74.294  112.130 119.499 1.00 57.01  ?  74  LEU B CB  1 
ATOM   2449 C CG  . LEU B 2 80  ? 73.124  112.682 118.680 1.00 57.01  ?  74  LEU B CG  1 
ATOM   2450 C CD1 . LEU B 2 80  ? 72.565  113.940 119.326 1.00 57.01  ?  74  LEU B CD1 1 
ATOM   2451 C CD2 . LEU B 2 80  ? 73.547  112.960 117.246 1.00 57.01  ?  74  LEU B CD2 1 
ATOM   2452 N N   . LEU B 2 81  ? 77.333  110.828 119.511 1.00 57.44  ?  75  LEU B N   1 
ATOM   2453 C CA  . LEU B 2 81  ? 78.521  110.433 120.262 1.00 57.44  ?  75  LEU B CA  1 
ATOM   2454 C C   . LEU B 2 81  ? 79.387  111.659 120.507 1.00 57.44  ?  75  LEU B C   1 
ATOM   2455 O O   . LEU B 2 81  ? 79.857  112.286 119.554 1.00 57.44  ?  75  LEU B O   1 
ATOM   2456 C CB  . LEU B 2 81  ? 79.312  109.360 119.508 1.00 57.44  ?  75  LEU B CB  1 
ATOM   2457 C CG  . LEU B 2 81  ? 80.679  108.995 120.089 1.00 57.44  ?  75  LEU B CG  1 
ATOM   2458 C CD1 . LEU B 2 81  ? 80.548  108.521 121.527 1.00 57.44  ?  75  LEU B CD1 1 
ATOM   2459 C CD2 . LEU B 2 81  ? 81.350  107.935 119.233 1.00 57.44  ?  75  LEU B CD2 1 
ATOM   2460 N N   . VAL B 2 82  ? 79.603  111.992 121.775 1.00 57.24  ?  76  VAL B N   1 
ATOM   2461 C CA  . VAL B 2 82  ? 80.444  113.123 122.153 1.00 57.24  ?  76  VAL B CA  1 
ATOM   2462 C C   . VAL B 2 82  ? 81.881  112.643 122.298 1.00 57.24  ?  76  VAL B C   1 
ATOM   2463 O O   . VAL B 2 82  ? 82.138  111.557 122.831 1.00 57.24  ?  76  VAL B O   1 
ATOM   2464 C CB  . VAL B 2 82  ? 79.939  113.778 123.454 1.00 57.24  ?  76  VAL B CB  1 
ATOM   2465 C CG1 . VAL B 2 82  ? 79.972  112.789 124.615 1.00 57.24  ?  76  VAL B CG1 1 
ATOM   2466 C CG2 . VAL B 2 82  ? 80.761  115.017 123.781 1.00 57.24  ?  76  VAL B CG2 1 
ATOM   2467 N N   . SER B 2 83  ? 82.824  113.452 121.818 1.00 58.34  ?  77  SER B N   1 
ATOM   2468 C CA  . SER B 2 83  ? 84.239  113.115 121.919 1.00 58.34  ?  77  SER B CA  1 
ATOM   2469 C C   . SER B 2 83  ? 85.053  114.395 122.043 1.00 58.34  ?  77  SER B C   1 
ATOM   2470 O O   . SER B 2 83  ? 84.853  115.336 121.270 1.00 58.34  ?  77  SER B O   1 
ATOM   2471 C CB  . SER B 2 83  ? 84.698  112.305 120.701 1.00 58.34  ?  77  SER B CB  1 
ATOM   2472 O OG  . SER B 2 83  ? 84.323  112.945 119.494 1.00 58.34  ?  77  SER B OG  1 
ATOM   2473 N N   . ALA B 2 84  ? 85.970  114.420 123.007 1.00 58.84  ?  78  ALA B N   1 
ATOM   2474 C CA  . ALA B 2 84  ? 86.804  115.582 123.277 1.00 58.84  ?  78  ALA B CA  1 
ATOM   2475 C C   . ALA B 2 84  ? 88.242  115.301 122.864 1.00 58.84  ?  78  ALA B C   1 
ATOM   2476 O O   . ALA B 2 84  ? 88.764  114.207 123.104 1.00 58.84  ?  78  ALA B O   1 
ATOM   2477 C CB  . ALA B 2 84  ? 86.758  115.956 124.760 1.00 58.84  ?  78  ALA B CB  1 
ATOM   2478 N N   . SER B 2 85  ? 88.881  116.295 122.251 1.00 60.03  ?  79  SER B N   1 
ATOM   2479 C CA  . SER B 2 85  ? 90.266  116.193 121.820 1.00 60.03  ?  79  SER B CA  1 
ATOM   2480 C C   . SER B 2 85  ? 91.139  117.139 122.634 1.00 60.03  ?  79  SER B C   1 
ATOM   2481 O O   . SER B 2 85  ? 90.672  118.165 123.137 1.00 60.03  ?  79  SER B O   1 
ATOM   2482 C CB  . SER B 2 85  ? 90.403  116.512 120.328 1.00 60.03  ?  79  SER B CB  1 
ATOM   2483 O OG  . SER B 2 85  ? 89.829  117.769 120.023 1.00 60.03  ?  79  SER B OG  1 
ATOM   2484 N N   . GLN B 2 86  ? 92.421  116.788 122.749 1.00 61.14  ?  80  GLN B N   1 
ATOM   2485 C CA  . GLN B 2 86  ? 93.363  117.550 123.563 1.00 61.14  ?  80  GLN B CA  1 
ATOM   2486 C C   . GLN B 2 86  ? 93.653  118.941 123.012 1.00 61.14  ?  80  GLN B C   1 
ATOM   2487 O O   . GLN B 2 86  ? 94.443  119.668 123.626 1.00 61.14  ?  80  GLN B O   1 
ATOM   2488 C CB  . GLN B 2 86  ? 94.674  116.774 123.705 1.00 61.14  ?  80  GLN B CB  1 
ATOM   2489 C CG  . GLN B 2 86  ? 94.588  115.575 124.637 1.00 61.14  ?  80  GLN B CG  1 
ATOM   2490 C CD  . GLN B 2 86  ? 94.383  115.976 126.086 1.00 61.14  ?  80  GLN B CD  1 
ATOM   2491 O OE1 . GLN B 2 86  ? 95.341  116.260 126.804 1.00 61.14  ?  80  GLN B OE1 1 
ATOM   2492 N NE2 . GLN B 2 86  ? 93.129  116.001 126.521 1.00 61.14  ?  80  GLN B NE2 1 
ATOM   2493 N N   . ASP B 2 87  ? 93.059  119.331 121.887 1.00 59.92  ?  81  ASP B N   1 
ATOM   2494 C CA  . ASP B 2 87  ? 93.223  120.673 121.346 1.00 59.92  ?  81  ASP B CA  1 
ATOM   2495 C C   . ASP B 2 87  ? 92.111  121.620 121.779 1.00 59.92  ?  81  ASP B C   1 
ATOM   2496 O O   . ASP B 2 87  ? 92.002  122.721 121.229 1.00 59.92  ?  81  ASP B O   1 
ATOM   2497 C CB  . ASP B 2 87  ? 93.289  120.622 119.817 1.00 59.92  ?  81  ASP B CB  1 
ATOM   2498 C CG  . ASP B 2 87  ? 92.013  120.091 119.196 1.00 59.92  ?  81  ASP B CG  1 
ATOM   2499 O OD1 . ASP B 2 87  ? 91.347  119.249 119.832 1.00 59.92  ?  81  ASP B OD1 1 
ATOM   2500 O OD2 . ASP B 2 87  ? 91.675  120.517 118.071 1.00 59.92  ?  81  ASP B OD2 1 
ATOM   2501 N N   . GLY B 2 88  ? 91.288  121.221 122.747 1.00 60.20  ?  82  GLY B N   1 
ATOM   2502 C CA  . GLY B 2 88  ? 90.189  122.053 123.195 1.00 60.20  ?  82  GLY B CA  1 
ATOM   2503 C C   . GLY B 2 88  ? 89.041  122.064 122.208 1.00 60.20  ?  82  GLY B C   1 
ATOM   2504 O O   . GLY B 2 88  ? 88.537  123.130 121.841 1.00 60.20  ?  82  GLY B O   1 
ATOM   2505 N N   . LYS B 2 89  ? 88.619  120.879 121.771 1.00 58.26  ?  83  LYS B N   1 
ATOM   2506 C CA  . LYS B 2 89  ? 87.572  120.744 120.765 1.00 58.26  ?  83  LYS B CA  1 
ATOM   2507 C C   . LYS B 2 89  ? 86.674  119.574 121.135 1.00 58.26  ?  83  LYS B C   1 
ATOM   2508 O O   . LYS B 2 89  ? 87.152  118.443 121.280 1.00 58.26  ?  83  LYS B O   1 
ATOM   2509 C CB  . LYS B 2 89  ? 88.173  120.534 119.372 1.00 58.26  ?  83  LYS B CB  1 
ATOM   2510 C CG  . LYS B 2 89  ? 88.690  121.801 118.712 1.00 58.26  ?  83  LYS B CG  1 
ATOM   2511 C CD  . LYS B 2 89  ? 87.571  122.559 118.018 1.00 58.26  ?  83  LYS B CD  1 
ATOM   2512 C CE  . LYS B 2 89  ? 88.089  123.806 117.321 1.00 58.26  ?  83  LYS B CE  1 
ATOM   2513 N NZ  . LYS B 2 89  ? 87.032  124.472 116.511 1.00 58.26  1  83  LYS B NZ  1 
ATOM   2514 N N   . LEU B 2 90  ? 85.381  119.846 121.287 1.00 58.85  ?  84  LEU B N   1 
ATOM   2515 C CA  . LEU B 2 90  ? 84.376  118.809 121.458 1.00 58.85  ?  84  LEU B CA  1 
ATOM   2516 C C   . LEU B 2 90  ? 83.666  118.587 120.130 1.00 58.85  ?  84  LEU B C   1 
ATOM   2517 O O   . LEU B 2 90  ? 83.423  119.537 119.381 1.00 58.85  ?  84  LEU B O   1 
ATOM   2518 C CB  . LEU B 2 90  ? 83.356  119.192 122.532 1.00 58.85  ?  84  LEU B CB  1 
ATOM   2519 C CG  . LEU B 2 90  ? 83.911  119.589 123.900 1.00 58.85  ?  84  LEU B CG  1 
ATOM   2520 C CD1 . LEU B 2 90  ? 82.776  119.968 124.837 1.00 58.85  ?  84  LEU B CD1 1 
ATOM   2521 C CD2 . LEU B 2 90  ? 84.741  118.464 124.491 1.00 58.85  ?  84  LEU B CD2 1 
ATOM   2522 N N   . ILE B 2 91  ? 83.334  117.332 119.839 1.00 57.48  ?  85  ILE B N   1 
ATOM   2523 C CA  . ILE B 2 91  ? 82.670  116.982 118.590 1.00 57.48  ?  85  ILE B CA  1 
ATOM   2524 C C   . ILE B 2 91  ? 81.565  115.984 118.906 1.00 57.48  ?  85  ILE B C   1 
ATOM   2525 O O   . ILE B 2 91  ? 81.822  114.940 119.516 1.00 57.48  ?  85  ILE B O   1 
ATOM   2526 C CB  . ILE B 2 91  ? 83.642  116.394 117.552 1.00 57.48  ?  85  ILE B CB  1 
ATOM   2527 C CG1 . ILE B 2 91  ? 84.913  117.246 117.468 1.00 57.48  ?  85  ILE B CG1 1 
ATOM   2528 C CG2 . ILE B 2 91  ? 82.968  116.322 116.188 1.00 57.48  ?  85  ILE B CG2 1 
ATOM   2529 C CD1 . ILE B 2 91  ? 85.936  116.732 116.476 1.00 57.48  ?  85  ILE B CD1 1 
ATOM   2530 N N   . ILE B 2 92  ? 80.342  116.314 118.510 1.00 57.04  ?  86  ILE B N   1 
ATOM   2531 C CA  . ILE B 2 92  ? 79.202  115.412 118.599 1.00 57.04  ?  86  ILE B CA  1 
ATOM   2532 C C   . ILE B 2 92  ? 78.990  114.837 117.206 1.00 57.04  ?  86  ILE B C   1 
ATOM   2533 O O   . ILE B 2 92  ? 78.534  115.544 116.299 1.00 57.04  ?  86  ILE B O   1 
ATOM   2534 C CB  . ILE B 2 92  ? 77.942  116.130 119.103 1.00 57.04  ?  86  ILE B CB  1 
ATOM   2535 C CG1 . ILE B 2 92  ? 78.264  117.001 120.322 1.00 57.04  ?  86  ILE B CG1 1 
ATOM   2536 C CG2 . ILE B 2 92  ? 76.855  115.119 119.439 1.00 57.04  ?  86  ILE B CG2 1 
ATOM   2537 C CD1 . ILE B 2 92  ? 78.909  116.251 121.467 1.00 57.04  ?  86  ILE B CD1 1 
ATOM   2538 N N   . TRP B 2 93  ? 79.345  113.566 117.041 1.00 56.78  ?  87  TRP B N   1 
ATOM   2539 C CA  . TRP B 2 93  ? 79.227  112.855 115.778 1.00 56.78  ?  87  TRP B CA  1 
ATOM   2540 C C   . TRP B 2 93  ? 77.905  112.104 115.700 1.00 56.78  ?  87  TRP B C   1 
ATOM   2541 O O   . TRP B 2 93  ? 77.329  111.709 116.719 1.00 56.78  ?  87  TRP B O   1 
ATOM   2542 C CB  . TRP B 2 93  ? 80.370  111.851 115.611 1.00 56.78  ?  87  TRP B CB  1 
ATOM   2543 C CG  . TRP B 2 93  ? 81.740  112.444 115.578 1.00 56.78  ?  87  TRP B CG  1 
ATOM   2544 C CD1 . TRP B 2 93  ? 82.445  112.944 116.633 1.00 56.78  ?  87  TRP B CD1 1 
ATOM   2545 C CD2 . TRP B 2 93  ? 82.587  112.575 114.431 1.00 56.78  ?  87  TRP B CD2 1 
ATOM   2546 N NE1 . TRP B 2 93  ? 83.676  113.386 116.212 1.00 56.78  ?  87  TRP B NE1 1 
ATOM   2547 C CE2 . TRP B 2 93  ? 83.787  113.171 114.864 1.00 56.78  ?  87  TRP B CE2 1 
ATOM   2548 C CE3 . TRP B 2 93  ? 82.445  112.249 113.079 1.00 56.78  ?  87  TRP B CE3 1 
ATOM   2549 C CZ2 . TRP B 2 93  ? 84.837  113.450 113.993 1.00 56.78  ?  87  TRP B CZ2 1 
ATOM   2550 C CZ3 . TRP B 2 93  ? 83.488  112.527 112.217 1.00 56.78  ?  87  TRP B CZ3 1 
ATOM   2551 C CH2 . TRP B 2 93  ? 84.669  113.120 112.677 1.00 56.78  ?  87  TRP B CH2 1 
ATOM   2552 N N   . ASP B 2 94  ? 77.441  111.895 114.469 1.00 56.37  ?  88  ASP B N   1 
ATOM   2553 C CA  . ASP B 2 94  ? 76.305  111.019 114.188 1.00 56.37  ?  88  ASP B CA  1 
ATOM   2554 C C   . ASP B 2 94  ? 76.863  109.629 113.907 1.00 56.37  ?  88  ASP B C   1 
ATOM   2555 O O   . ASP B 2 94  ? 77.454  109.385 112.852 1.00 56.37  ?  88  ASP B O   1 
ATOM   2556 C CB  . ASP B 2 94  ? 75.491  111.549 113.012 1.00 56.37  ?  88  ASP B CB  1 
ATOM   2557 C CG  . ASP B 2 94  ? 74.283  110.687 112.700 1.00 56.37  ?  88  ASP B CG  1 
ATOM   2558 O OD1 . ASP B 2 94  ? 74.077  109.669 113.392 1.00 56.37  ?  88  ASP B OD1 1 
ATOM   2559 O OD2 . ASP B 2 94  ? 73.538  111.029 111.758 1.00 56.37  ?  88  ASP B OD2 1 
ATOM   2560 N N   . SER B 2 95  ? 76.676  108.711 114.858 1.00 57.07  ?  89  SER B N   1 
ATOM   2561 C CA  . SER B 2 95  ? 77.270  107.384 114.731 1.00 57.07  ?  89  SER B CA  1 
ATOM   2562 C C   . SER B 2 95  ? 76.777  106.670 113.477 1.00 57.07  ?  89  SER B C   1 
ATOM   2563 O O   . SER B 2 95  ? 77.542  105.954 112.821 1.00 57.07  ?  89  SER B O   1 
ATOM   2564 C CB  . SER B 2 95  ? 76.959  106.552 115.975 1.00 57.07  ?  89  SER B CB  1 
ATOM   2565 O OG  . SER B 2 95  ? 75.563  106.373 116.132 1.00 57.07  ?  89  SER B OG  1 
ATOM   2566 N N   . TYR B 2 96  ? 75.503  106.851 113.127 1.00 55.99  ?  90  TYR B N   1 
ATOM   2567 C CA  . TYR B 2 96  ? 74.941  106.139 111.983 1.00 55.99  ?  90  TYR B CA  1 
ATOM   2568 C C   . TYR B 2 96  ? 75.494  106.682 110.671 1.00 55.99  ?  90  TYR B C   1 
ATOM   2569 O O   . TYR B 2 96  ? 76.114  105.949 109.892 1.00 55.99  ?  90  TYR B O   1 
ATOM   2570 C CB  . TYR B 2 96  ? 73.413  106.233 112.005 1.00 55.99  ?  90  TYR B CB  1 
ATOM   2571 C CG  . TYR B 2 96  ? 72.761  105.604 113.220 1.00 55.99  ?  90  TYR B CG  1 
ATOM   2572 C CD1 . TYR B 2 96  ? 73.459  104.723 114.039 1.00 55.99  ?  90  TYR B CD1 1 
ATOM   2573 C CD2 . TYR B 2 96  ? 71.441  105.889 113.544 1.00 55.99  ?  90  TYR B CD2 1 
ATOM   2574 C CE1 . TYR B 2 96  ? 72.862  104.150 115.145 1.00 55.99  ?  90  TYR B CE1 1 
ATOM   2575 C CE2 . TYR B 2 96  ? 70.836  105.320 114.649 1.00 55.99  ?  90  TYR B CE2 1 
ATOM   2576 C CZ  . TYR B 2 96  ? 71.551  104.451 115.445 1.00 55.99  ?  90  TYR B CZ  1 
ATOM   2577 O OH  . TYR B 2 96  ? 70.952  103.882 116.546 1.00 55.99  ?  90  TYR B OH  1 
ATOM   2578 N N   . THR B 2 97  ? 75.280  107.970 110.407 1.00 55.80  ?  91  THR B N   1 
ATOM   2579 C CA  . THR B 2 97  ? 75.690  108.576 109.147 1.00 55.80  ?  91  THR B CA  1 
ATOM   2580 C C   . THR B 2 97  ? 77.133  109.063 109.154 1.00 55.80  ?  91  THR B C   1 
ATOM   2581 O O   . THR B 2 97  ? 77.632  109.478 108.103 1.00 55.80  ?  91  THR B O   1 
ATOM   2582 C CB  . THR B 2 97  ? 74.769  109.752 108.801 1.00 55.80  ?  91  THR B CB  1 
ATOM   2583 O OG1 . THR B 2 97  ? 74.855  110.750 109.827 1.00 55.80  ?  91  THR B OG1 1 
ATOM   2584 C CG2 . THR B 2 97  ? 73.327  109.284 108.669 1.00 55.80  ?  91  THR B CG2 1 
ATOM   2585 N N   . THR B 2 98  ? 77.811  109.028 110.301 1.00 56.37  ?  92  THR B N   1 
ATOM   2586 C CA  . THR B 2 98  ? 79.196  109.459 110.468 1.00 56.37  ?  92  THR B CA  1 
ATOM   2587 C C   . THR B 2 98  ? 79.349  110.973 110.386 1.00 56.37  ?  92  THR B C   1 
ATOM   2588 O O   . THR B 2 98  ? 80.465  111.478 110.559 1.00 56.37  ?  92  THR B O   1 
ATOM   2589 C CB  . THR B 2 98  ? 80.131  108.815 109.433 1.00 56.37  ?  92  THR B CB  1 
ATOM   2590 O OG1 . THR B 2 98  ? 79.788  107.435 109.266 1.00 56.37  ?  92  THR B OG1 1 
ATOM   2591 C CG2 . THR B 2 98  ? 81.585  108.916 109.877 1.00 56.37  ?  92  THR B CG2 1 
ATOM   2592 N N   . ASN B 2 99  ? 78.273  111.715 110.141 1.00 56.83  ?  93  ASN B N   1 
ATOM   2593 C CA  . ASN B 2 99  ? 78.375  113.159 110.008 1.00 56.83  ?  93  ASN B CA  1 
ATOM   2594 C C   . ASN B 2 99  ? 78.668  113.805 111.360 1.00 56.83  ?  93  ASN B C   1 
ATOM   2595 O O   . ASN B 2 99  ? 78.479  113.208 112.423 1.00 56.83  ?  93  ASN B O   1 
ATOM   2596 C CB  . ASN B 2 99  ? 77.086  113.734 109.422 1.00 56.83  ?  93  ASN B CB  1 
ATOM   2597 C CG  . ASN B 2 99  ? 76.750  113.148 108.065 1.00 56.83  ?  93  ASN B CG  1 
ATOM   2598 O OD1 . ASN B 2 99  ? 77.639  112.792 107.292 1.00 56.83  ?  93  ASN B OD1 1 
ATOM   2599 N ND2 . ASN B 2 99  ? 75.460  113.043 107.769 1.00 56.83  ?  93  ASN B ND2 1 
ATOM   2600 N N   . LYS B 2 100 ? 79.137  115.049 111.303 1.00 57.67  ?  94  LYS B N   1 
ATOM   2601 C CA  . LYS B 2 100 ? 79.447  115.826 112.498 1.00 57.67  ?  94  LYS B CA  1 
ATOM   2602 C C   . LYS B 2 100 ? 78.216  116.640 112.876 1.00 57.67  ?  94  LYS B C   1 
ATOM   2603 O O   . LYS B 2 100 ? 77.876  117.617 112.200 1.00 57.67  ?  94  LYS B O   1 
ATOM   2604 C CB  . LYS B 2 100 ? 80.652  116.730 112.254 1.00 57.67  ?  94  LYS B CB  1 
ATOM   2605 C CG  . LYS B 2 100 ? 81.920  115.981 111.889 1.00 57.67  ?  94  LYS B CG  1 
ATOM   2606 C CD  . LYS B 2 100 ? 83.037  116.937 111.513 1.00 57.67  ?  94  LYS B CD  1 
ATOM   2607 C CE  . LYS B 2 100 ? 84.323  116.195 111.196 1.00 57.67  ?  94  LYS B CE  1 
ATOM   2608 N NZ  . LYS B 2 100 ? 84.124  115.131 110.173 1.00 57.67  1  94  LYS B NZ  1 
ATOM   2609 N N   . VAL B 2 101 ? 77.548  116.240 113.959 1.00 56.49  ?  95  VAL B N   1 
ATOM   2610 C CA  . VAL B 2 101 ? 76.331  116.931 114.370 1.00 56.49  ?  95  VAL B CA  1 
ATOM   2611 C C   . VAL B 2 101 ? 76.669  118.280 114.993 1.00 56.49  ?  95  VAL B C   1 
ATOM   2612 O O   . VAL B 2 101 ? 75.983  119.279 114.749 1.00 56.49  ?  95  VAL B O   1 
ATOM   2613 C CB  . VAL B 2 101 ? 75.517  116.049 115.334 1.00 56.49  ?  95  VAL B CB  1 
ATOM   2614 C CG1 . VAL B 2 101 ? 74.145  116.667 115.599 1.00 56.49  ?  95  VAL B CG1 1 
ATOM   2615 C CG2 . VAL B 2 101 ? 75.386  114.637 114.778 1.00 56.49  ?  95  VAL B CG2 1 
ATOM   2616 N N   . HIS B 2 102 ? 77.724  118.334 115.804 1.00 57.77  ?  96  HIS B N   1 
ATOM   2617 C CA  . HIS B 2 102 ? 78.098  119.578 116.464 1.00 57.77  ?  96  HIS B CA  1 
ATOM   2618 C C   . HIS B 2 102 ? 79.607  119.648 116.640 1.00 57.77  ?  96  HIS B C   1 
ATOM   2619 O O   . HIS B 2 102 ? 80.277  118.626 116.802 1.00 57.77  ?  96  HIS B O   1 
ATOM   2620 C CB  . HIS B 2 102 ? 77.415  119.723 117.831 1.00 57.77  ?  96  HIS B CB  1 
ATOM   2621 C CG  . HIS B 2 102 ? 75.932  119.910 117.752 1.00 57.77  ?  96  HIS B CG  1 
ATOM   2622 N ND1 . HIS B 2 102 ? 75.056  118.858 117.599 1.00 57.77  ?  96  HIS B ND1 1 
ATOM   2623 C CD2 . HIS B 2 102 ? 75.172  121.029 117.804 1.00 57.77  ?  96  HIS B CD2 1 
ATOM   2624 C CE1 . HIS B 2 102 ? 73.819  119.321 117.562 1.00 57.77  ?  96  HIS B CE1 1 
ATOM   2625 N NE2 . HIS B 2 102 ? 73.861  120.635 117.684 1.00 57.77  ?  96  HIS B NE2 1 
ATOM   2626 N N   . ALA B 2 103 ? 80.130  120.874 116.625 1.00 57.07  ?  97  ALA B N   1 
ATOM   2627 C CA  . ALA B 2 103 ? 81.541  121.138 116.887 1.00 57.07  ?  97  ALA B CA  1 
ATOM   2628 C C   . ALA B 2 103 ? 81.634  122.336 117.819 1.00 57.07  ?  97  ALA B C   1 
ATOM   2629 O O   . ALA B 2 103 ? 81.114  123.410 117.500 1.00 57.07  ?  97  ALA B O   1 
ATOM   2630 C CB  . ALA B 2 103 ? 82.309  121.402 115.588 1.00 57.07  ?  97  ALA B CB  1 
ATOM   2631 N N   . ILE B 2 104 ? 82.291  122.155 118.960 1.00 58.08  ?  98  ILE B N   1 
ATOM   2632 C CA  . ILE B 2 104 ? 82.368  123.163 120.008 1.00 58.08  ?  98  ILE B CA  1 
ATOM   2633 C C   . ILE B 2 104 ? 83.840  123.474 120.262 1.00 58.08  ?  98  ILE B C   1 
ATOM   2634 O O   . ILE B 2 104 ? 84.587  122.595 120.704 1.00 58.08  ?  98  ILE B O   1 
ATOM   2635 C CB  . ILE B 2 104 ? 81.685  122.698 121.305 1.00 58.08  ?  98  ILE B CB  1 
ATOM   2636 C CG1 . ILE B 2 104 ? 80.273  122.181 121.013 1.00 58.08  ?  98  ILE B CG1 1 
ATOM   2637 C CG2 . ILE B 2 104 ? 81.637  123.838 122.316 1.00 58.08  ?  98  ILE B CG2 1 
ATOM   2638 C CD1 . ILE B 2 104 ? 79.593  121.539 122.206 1.00 58.08  ?  98  ILE B CD1 1 
ATOM   2639 N N   . PRO B 2 105 ? 84.310  124.696 119.997 1.00 58.40  ?  99  PRO B N   1 
ATOM   2640 C CA  . PRO B 2 105 ? 85.679  125.067 120.386 1.00 58.40  ?  99  PRO B CA  1 
ATOM   2641 C C   . PRO B 2 105 ? 85.727  125.467 121.854 1.00 58.40  ?  99  PRO B C   1 
ATOM   2642 O O   . PRO B 2 105 ? 84.994  126.357 122.291 1.00 58.40  ?  99  PRO B O   1 
ATOM   2643 C CB  . PRO B 2 105 ? 85.998  126.252 119.467 1.00 58.40  ?  99  PRO B CB  1 
ATOM   2644 C CG  . PRO B 2 105 ? 84.673  126.879 119.214 1.00 58.40  ?  99  PRO B CG  1 
ATOM   2645 C CD  . PRO B 2 105 ? 83.661  125.758 119.205 1.00 58.40  ?  99  PRO B CD  1 
ATOM   2646 N N   . LEU B 2 106 ? 86.595  124.807 122.616 1.00 59.20  ?  100 LEU B N   1 
ATOM   2647 C CA  . LEU B 2 106 ? 86.723  125.067 124.043 1.00 59.20  ?  100 LEU B CA  1 
ATOM   2648 C C   . LEU B 2 106 ? 87.781  126.130 124.298 1.00 59.20  ?  100 LEU B C   1 
ATOM   2649 O O   . LEU B 2 106 ? 88.787  126.210 123.586 1.00 59.20  ?  100 LEU B O   1 
ATOM   2650 C CB  . LEU B 2 106 ? 87.087  123.785 124.794 1.00 59.20  ?  100 LEU B CB  1 
ATOM   2651 C CG  . LEU B 2 106 ? 86.068  122.646 124.737 1.00 59.20  ?  100 LEU B CG  1 
ATOM   2652 C CD1 . LEU B 2 106 ? 86.578  121.446 125.518 1.00 59.20  ?  100 LEU B CD1 1 
ATOM   2653 C CD2 . LEU B 2 106 ? 84.716  123.098 125.268 1.00 59.20  ?  100 LEU B CD2 1 
ATOM   2654 N N   . ARG B 2 107 ? 87.546  126.950 125.325 1.00 63.22  ?  101 ARG B N   1 
ATOM   2655 C CA  . ARG B 2 107 ? 88.529  127.951 125.718 1.00 63.22  ?  101 ARG B CA  1 
ATOM   2656 C C   . ARG B 2 107 ? 89.741  127.328 126.397 1.00 63.22  ?  101 ARG B C   1 
ATOM   2657 O O   . ARG B 2 107 ? 90.776  127.991 126.521 1.00 63.22  ?  101 ARG B O   1 
ATOM   2658 C CB  . ARG B 2 107 ? 87.886  128.981 126.649 1.00 63.22  ?  101 ARG B CB  1 
ATOM   2659 C CG  . ARG B 2 107 ? 86.749  129.764 126.012 1.00 63.22  ?  101 ARG B CG  1 
ATOM   2660 C CD  . ARG B 2 107 ? 86.119  130.732 127.000 1.00 63.22  ?  101 ARG B CD  1 
ATOM   2661 N NE  . ARG B 2 107 ? 85.048  131.516 126.391 1.00 63.22  ?  101 ARG B NE  1 
ATOM   2662 C CZ  . ARG B 2 107 ? 84.313  132.414 127.041 1.00 63.22  ?  101 ARG B CZ  1 
ATOM   2663 N NH1 . ARG B 2 107 ? 84.526  132.648 128.329 1.00 63.22  1  101 ARG B NH1 1 
ATOM   2664 N NH2 . ARG B 2 107 ? 83.361  133.079 126.400 1.00 63.22  ?  101 ARG B NH2 1 
ATOM   2665 N N   . SER B 2 108 ? 89.635  126.076 126.836 1.00 61.67  ?  102 SER B N   1 
ATOM   2666 C CA  . SER B 2 108 ? 90.739  125.349 127.446 1.00 61.67  ?  102 SER B CA  1 
ATOM   2667 C C   . SER B 2 108 ? 91.224  124.280 126.479 1.00 61.67  ?  102 SER B C   1 
ATOM   2668 O O   . SER B 2 108 ? 90.424  123.484 125.974 1.00 61.67  ?  102 SER B O   1 
ATOM   2669 C CB  . SER B 2 108 ? 90.311  124.711 128.770 1.00 61.67  ?  102 SER B CB  1 
ATOM   2670 O OG  . SER B 2 108 ? 91.362  123.938 129.324 1.00 61.67  ?  102 SER B OG  1 
ATOM   2671 N N   . SER B 2 109 ? 92.533  124.263 126.222 1.00 61.51  ?  103 SER B N   1 
ATOM   2672 C CA  . SER B 2 109 ? 93.089  123.301 125.278 1.00 61.51  ?  103 SER B CA  1 
ATOM   2673 C C   . SER B 2 109 ? 93.161  121.902 125.878 1.00 61.51  ?  103 SER B C   1 
ATOM   2674 O O   . SER B 2 109 ? 92.841  120.918 125.203 1.00 61.51  ?  103 SER B O   1 
ATOM   2675 C CB  . SER B 2 109 ? 94.477  123.756 124.826 1.00 61.51  ?  103 SER B CB  1 
ATOM   2676 O OG  . SER B 2 109 ? 95.042  122.834 123.911 1.00 61.51  ?  103 SER B OG  1 
ATOM   2677 N N   . TRP B 2 110 ? 93.569  121.794 127.144 1.00 61.53  ?  104 TRP B N   1 
ATOM   2678 C CA  . TRP B 2 110 ? 93.759  120.495 127.790 1.00 61.53  ?  104 TRP B CA  1 
ATOM   2679 C C   . TRP B 2 110 ? 92.443  120.061 128.428 1.00 61.53  ?  104 TRP B C   1 
ATOM   2680 O O   . TRP B 2 110 ? 92.174  120.291 129.609 1.00 61.53  ?  104 TRP B O   1 
ATOM   2681 C CB  . TRP B 2 110 ? 94.885  120.569 128.813 1.00 61.53  ?  104 TRP B CB  1 
ATOM   2682 C CG  . TRP B 2 110 ? 96.180  121.053 128.239 1.00 61.53  ?  104 TRP B CG  1 
ATOM   2683 C CD1 . TRP B 2 110 ? 96.714  122.303 128.361 1.00 61.53  ?  104 TRP B CD1 1 
ATOM   2684 C CD2 . TRP B 2 110 ? 97.104  120.298 127.446 1.00 61.53  ?  104 TRP B CD2 1 
ATOM   2685 N NE1 . TRP B 2 110 ? 97.914  122.372 127.696 1.00 61.53  ?  104 TRP B NE1 1 
ATOM   2686 C CE2 . TRP B 2 110 ? 98.176  121.154 127.125 1.00 61.53  ?  104 TRP B CE2 1 
ATOM   2687 C CE3 . TRP B 2 110 ? 97.129  118.981 126.977 1.00 61.53  ?  104 TRP B CE3 1 
ATOM   2688 C CZ2 . TRP B 2 110 ? 99.261  120.737 126.358 1.00 61.53  ?  104 TRP B CZ2 1 
ATOM   2689 C CZ3 . TRP B 2 110 ? 98.208  118.569 126.215 1.00 61.53  ?  104 TRP B CZ3 1 
ATOM   2690 C CH2 . TRP B 2 110 ? 99.258  119.444 125.913 1.00 61.53  ?  104 TRP B CH2 1 
ATOM   2691 N N   . VAL B 2 111 ? 91.608  119.416 127.617 1.00 59.49  ?  105 VAL B N   1 
ATOM   2692 C CA  . VAL B 2 111 ? 90.344  118.845 128.067 1.00 59.49  ?  105 VAL B CA  1 
ATOM   2693 C C   . VAL B 2 111 ? 90.524  117.339 128.195 1.00 59.49  ?  105 VAL B C   1 
ATOM   2694 O O   . VAL B 2 111 ? 91.037  116.687 127.276 1.00 59.49  ?  105 VAL B O   1 
ATOM   2695 C CB  . VAL B 2 111 ? 89.197  119.189 127.100 1.00 59.49  ?  105 VAL B CB  1 
ATOM   2696 C CG1 . VAL B 2 111 ? 89.439  118.576 125.727 1.00 59.49  ?  105 VAL B CG1 1 
ATOM   2697 C CG2 . VAL B 2 111 ? 87.860  118.727 127.667 1.00 59.49  ?  105 VAL B CG2 1 
ATOM   2698 N N   . MET B 2 112 ? 90.109  116.786 129.335 1.00 60.18  ?  106 MET B N   1 
ATOM   2699 C CA  . MET B 2 112 ? 90.291  115.372 129.625 1.00 60.18  ?  106 MET B CA  1 
ATOM   2700 C C   . MET B 2 112 ? 88.991  114.649 129.943 1.00 60.18  ?  106 MET B C   1 
ATOM   2701 O O   . MET B 2 112 ? 89.015  113.430 130.154 1.00 60.18  ?  106 MET B O   1 
ATOM   2702 C CB  . MET B 2 112 ? 91.263  115.195 130.800 1.00 60.18  ?  106 MET B CB  1 
ATOM   2703 C CG  . MET B 2 112 ? 92.625  115.834 130.577 1.00 60.18  ?  106 MET B CG  1 
ATOM   2704 S SD  . MET B 2 112 ? 93.743  115.615 131.975 1.00 60.18  ?  106 MET B SD  1 
ATOM   2705 C CE  . MET B 2 112 ? 92.858  116.485 133.266 1.00 60.18  ?  106 MET B CE  1 
ATOM   2706 N N   . THR B 2 113 ? 87.861  115.353 129.986 1.00 60.10  ?  107 THR B N   1 
ATOM   2707 C CA  . THR B 2 113 ? 86.584  114.744 130.322 1.00 60.10  ?  107 THR B CA  1 
ATOM   2708 C C   . THR B 2 113 ? 85.485  115.352 129.464 1.00 60.10  ?  107 THR B C   1 
ATOM   2709 O O   . THR B 2 113 ? 85.553  116.520 129.073 1.00 60.10  ?  107 THR B O   1 
ATOM   2710 C CB  . THR B 2 113 ? 86.239  114.929 131.808 1.00 60.10  ?  107 THR B CB  1 
ATOM   2711 O OG1 . THR B 2 113 ? 84.901  114.478 132.051 1.00 60.10  ?  107 THR B OG1 1 
ATOM   2712 C CG2 . THR B 2 113 ? 86.364  116.392 132.214 1.00 60.10  ?  107 THR B CG2 1 
ATOM   2713 N N   . CYS B 2 114 ? 84.471  114.541 129.174 1.00 58.09  ?  108 CYS B N   1 
ATOM   2714 C CA  . CYS B 2 114 ? 83.310  114.999 128.426 1.00 58.09  ?  108 CYS B CA  1 
ATOM   2715 C C   . CYS B 2 114 ? 82.168  114.024 128.663 1.00 58.09  ?  108 CYS B C   1 
ATOM   2716 O O   . CYS B 2 114 ? 82.384  112.817 128.798 1.00 58.09  ?  108 CYS B O   1 
ATOM   2717 C CB  . CYS B 2 114 ? 83.611  115.118 126.928 1.00 58.09  ?  108 CYS B CB  1 
ATOM   2718 S SG  . CYS B 2 114 ? 83.835  113.535 126.086 1.00 58.09  ?  108 CYS B SG  1 
ATOM   2719 N N   . ALA B 2 115 ? 80.952  114.562 128.711 1.00 58.34  ?  109 ALA B N   1 
ATOM   2720 C CA  . ALA B 2 115 ? 79.767  113.753 128.948 1.00 58.34  ?  109 ALA B CA  1 
ATOM   2721 C C   . ALA B 2 115 ? 78.579  114.396 128.250 1.00 58.34  ?  109 ALA B C   1 
ATOM   2722 O O   . ALA B 2 115 ? 78.556  115.608 128.019 1.00 58.34  ?  109 ALA B O   1 
ATOM   2723 C CB  . ALA B 2 115 ? 79.481  113.597 130.446 1.00 58.34  ?  109 ALA B CB  1 
ATOM   2724 N N   . TYR B 2 116 ? 77.592  113.568 127.917 1.00 57.48  ?  110 TYR B N   1 
ATOM   2725 C CA  . TYR B 2 116 ? 76.379  114.008 127.241 1.00 57.48  ?  110 TYR B CA  1 
ATOM   2726 C C   . TYR B 2 116 ? 75.212  113.876 128.211 1.00 57.48  ?  110 TYR B C   1 
ATOM   2727 O O   . TYR B 2 116 ? 74.941  112.779 128.713 1.00 57.48  ?  110 TYR B O   1 
ATOM   2728 C CB  . TYR B 2 116 ? 76.130  113.184 125.977 1.00 57.48  ?  110 TYR B CB  1 
ATOM   2729 C CG  . TYR B 2 116 ? 75.393  113.923 124.879 1.00 57.48  ?  110 TYR B CG  1 
ATOM   2730 C CD1 . TYR B 2 116 ? 74.540  114.980 125.171 1.00 57.48  ?  110 TYR B CD1 1 
ATOM   2731 C CD2 . TYR B 2 116 ? 75.555  113.563 123.548 1.00 57.48  ?  110 TYR B CD2 1 
ATOM   2732 C CE1 . TYR B 2 116 ? 73.870  115.655 124.169 1.00 57.48  ?  110 TYR B CE1 1 
ATOM   2733 C CE2 . TYR B 2 116 ? 74.888  114.232 122.539 1.00 57.48  ?  110 TYR B CE2 1 
ATOM   2734 C CZ  . TYR B 2 116 ? 74.047  115.276 122.856 1.00 57.48  ?  110 TYR B CZ  1 
ATOM   2735 O OH  . TYR B 2 116 ? 73.381  115.946 121.855 1.00 57.48  ?  110 TYR B OH  1 
ATOM   2736 N N   . ALA B 2 117 ? 74.533  114.989 128.475 1.00 57.15  ?  111 ALA B N   1 
ATOM   2737 C CA  . ALA B 2 117 ? 73.437  114.983 129.429 1.00 57.15  ?  111 ALA B CA  1 
ATOM   2738 C C   . ALA B 2 117 ? 72.371  113.970 129.009 1.00 57.15  ?  111 ALA B C   1 
ATOM   2739 O O   . ALA B 2 117 ? 72.228  113.663 127.821 1.00 57.15  ?  111 ALA B O   1 
ATOM   2740 C CB  . ALA B 2 117 ? 72.819  116.375 129.541 1.00 57.15  ?  111 ALA B CB  1 
ATOM   2741 N N   . PRO B 2 118 ? 71.606  113.433 129.965 1.00 57.82  ?  112 PRO B N   1 
ATOM   2742 C CA  . PRO B 2 118 ? 70.563  112.457 129.611 1.00 57.82  ?  112 PRO B CA  1 
ATOM   2743 C C   . PRO B 2 118 ? 69.396  113.057 128.845 1.00 57.82  ?  112 PRO B C   1 
ATOM   2744 O O   . PRO B 2 118 ? 68.569  112.297 128.325 1.00 57.82  ?  112 PRO B O   1 
ATOM   2745 C CB  . PRO B 2 118 ? 70.112  111.917 130.973 1.00 57.82  ?  112 PRO B CB  1 
ATOM   2746 C CG  . PRO B 2 118 ? 70.409  113.019 131.928 1.00 57.82  ?  112 PRO B CG  1 
ATOM   2747 C CD  . PRO B 2 118 ? 71.652  113.688 131.416 1.00 57.82  ?  112 PRO B CD  1 
ATOM   2748 N N   . SER B 2 119 ? 69.298  114.383 128.761 1.00 58.95  ?  113 SER B N   1 
ATOM   2749 C CA  . SER B 2 119 ? 68.234  115.035 128.010 1.00 58.95  ?  113 SER B CA  1 
ATOM   2750 C C   . SER B 2 119 ? 68.646  115.393 126.589 1.00 58.95  ?  113 SER B C   1 
ATOM   2751 O O   . SER B 2 119 ? 67.797  115.841 125.810 1.00 58.95  ?  113 SER B O   1 
ATOM   2752 C CB  . SER B 2 119 ? 67.777  116.304 128.738 1.00 58.95  ?  113 SER B CB  1 
ATOM   2753 O OG  . SER B 2 119 ? 68.850  117.216 128.896 1.00 58.95  ?  113 SER B OG  1 
ATOM   2754 N N   . GLY B 2 120 ? 69.915  115.208 126.233 1.00 57.98  ?  114 GLY B N   1 
ATOM   2755 C CA  . GLY B 2 120 ? 70.379  115.537 124.901 1.00 57.98  ?  114 GLY B CA  1 
ATOM   2756 C C   . GLY B 2 120 ? 70.519  117.015 124.622 1.00 57.98  ?  114 GLY B C   1 
ATOM   2757 O O   . GLY B 2 120 ? 70.641  117.398 123.455 1.00 57.98  ?  114 GLY B O   1 
ATOM   2758 N N   . ASN B 2 121 ? 70.508  117.859 125.656 1.00 58.20  ?  115 ASN B N   1 
ATOM   2759 C CA  . ASN B 2 121 ? 70.578  119.303 125.481 1.00 58.20  ?  115 ASN B CA  1 
ATOM   2760 C C   . ASN B 2 121 ? 71.837  119.934 126.057 1.00 58.20  ?  115 ASN B C   1 
ATOM   2761 O O   . ASN B 2 121 ? 72.172  121.057 125.668 1.00 58.20  ?  115 ASN B O   1 
ATOM   2762 C CB  . ASN B 2 121 ? 69.357  119.975 126.126 1.00 58.20  ?  115 ASN B CB  1 
ATOM   2763 C CG  . ASN B 2 121 ? 68.047  119.509 125.523 1.00 58.20  ?  115 ASN B CG  1 
ATOM   2764 O OD1 . ASN B 2 121 ? 67.980  118.453 124.894 1.00 58.20  ?  115 ASN B OD1 1 
ATOM   2765 N ND2 . ASN B 2 121 ? 66.995  120.297 125.714 1.00 58.20  ?  115 ASN B ND2 1 
ATOM   2766 N N   . TYR B 2 122 ? 72.537  119.254 126.963 1.00 57.70  ?  116 TYR B N   1 
ATOM   2767 C CA  . TYR B 2 122 ? 73.714  119.806 127.616 1.00 57.70  ?  116 TYR B CA  1 
ATOM   2768 C C   . TYR B 2 122 ? 74.876  118.829 127.514 1.00 57.70  ?  116 TYR B C   1 
ATOM   2769 O O   . TYR B 2 122 ? 74.689  117.609 127.526 1.00 57.70  ?  116 TYR B O   1 
ATOM   2770 C CB  . TYR B 2 122 ? 73.438  120.128 129.091 1.00 57.70  ?  116 TYR B CB  1 
ATOM   2771 C CG  . TYR B 2 122 ? 72.424  121.231 129.296 1.00 57.70  ?  116 TYR B CG  1 
ATOM   2772 C CD1 . TYR B 2 122 ? 72.824  122.557 129.397 1.00 57.70  ?  116 TYR B CD1 1 
ATOM   2773 C CD2 . TYR B 2 122 ? 71.069  120.947 129.389 1.00 57.70  ?  116 TYR B CD2 1 
ATOM   2774 C CE1 . TYR B 2 122 ? 71.902  123.569 129.585 1.00 57.70  ?  116 TYR B CE1 1 
ATOM   2775 C CE2 . TYR B 2 122 ? 70.139  121.952 129.577 1.00 57.70  ?  116 TYR B CE2 1 
ATOM   2776 C CZ  . TYR B 2 122 ? 70.562  123.261 129.674 1.00 57.70  ?  116 TYR B CZ  1 
ATOM   2777 O OH  . TYR B 2 122 ? 69.640  124.266 129.860 1.00 57.70  ?  116 TYR B OH  1 
ATOM   2778 N N   . VAL B 2 123 ? 76.082  119.384 127.414 1.00 57.33  ?  117 VAL B N   1 
ATOM   2779 C CA  . VAL B 2 123 ? 77.314  118.602 127.350 1.00 57.33  ?  117 VAL B CA  1 
ATOM   2780 C C   . VAL B 2 123 ? 78.355  119.270 128.237 1.00 57.33  ?  117 VAL B C   1 
ATOM   2781 O O   . VAL B 2 123 ? 78.599  120.475 128.117 1.00 57.33  ?  117 VAL B O   1 
ATOM   2782 C CB  . VAL B 2 123 ? 77.841  118.467 125.907 1.00 57.33  ?  117 VAL B CB  1 
ATOM   2783 C CG1 . VAL B 2 123 ? 76.975  117.499 125.112 1.00 57.33  ?  117 VAL B CG1 1 
ATOM   2784 C CG2 . VAL B 2 123 ? 77.902  119.831 125.223 1.00 57.33  ?  117 VAL B CG2 1 
ATOM   2785 N N   . ALA B 2 124 ? 78.970  118.492 129.120 1.00 57.87  ?  118 ALA B N   1 
ATOM   2786 C CA  . ALA B 2 124 ? 79.965  118.995 130.055 1.00 57.87  ?  118 ALA B CA  1 
ATOM   2787 C C   . ALA B 2 124 ? 81.374  118.675 129.569 1.00 57.87  ?  118 ALA B C   1 
ATOM   2788 O O   . ALA B 2 124 ? 81.592  117.763 128.768 1.00 57.87  ?  118 ALA B O   1 
ATOM   2789 C CB  . ALA B 2 124 ? 79.749  118.398 131.448 1.00 57.87  ?  118 ALA B CB  1 
ATOM   2790 N N   . CYS B 2 125 ? 82.334  119.452 130.065 1.00 58.85  ?  119 CYS B N   1 
ATOM   2791 C CA  . CYS B 2 125 ? 83.736  119.226 129.748 1.00 58.85  ?  119 CYS B CA  1 
ATOM   2792 C C   . CYS B 2 125 ? 84.593  119.905 130.806 1.00 58.85  ?  119 CYS B C   1 
ATOM   2793 O O   . CYS B 2 125 ? 84.120  120.755 131.565 1.00 58.85  ?  119 CYS B O   1 
ATOM   2794 C CB  . CYS B 2 125 ? 84.088  119.748 128.351 1.00 58.85  ?  119 CYS B CB  1 
ATOM   2795 S SG  . CYS B 2 125 ? 83.899  121.534 128.160 1.00 58.85  ?  119 CYS B SG  1 
ATOM   2796 N N   . GLY B 2 126 ? 85.861  119.516 130.843 1.00 58.68  ?  120 GLY B N   1 
ATOM   2797 C CA  . GLY B 2 126 ? 86.789  120.083 131.804 1.00 58.68  ?  120 GLY B CA  1 
ATOM   2798 C C   . GLY B 2 126 ? 88.146  119.429 131.674 1.00 58.68  ?  120 GLY B C   1 
ATOM   2799 O O   . GLY B 2 126 ? 88.355  118.526 130.857 1.00 58.68  ?  120 GLY B O   1 
ATOM   2800 N N   . GLY B 2 127 ? 89.075  119.901 132.501 1.00 59.86  ?  121 GLY B N   1 
ATOM   2801 C CA  . GLY B 2 127 ? 90.424  119.371 132.492 1.00 59.86  ?  121 GLY B CA  1 
ATOM   2802 C C   . GLY B 2 127 ? 91.375  120.143 133.382 1.00 59.86  ?  121 GLY B C   1 
ATOM   2803 O O   . GLY B 2 127 ? 91.042  120.470 134.525 1.00 59.86  ?  121 GLY B O   1 
ATOM   2804 N N   . LEU B 2 128 ? 92.569  120.441 132.865 1.00 61.24  ?  122 LEU B N   1 
ATOM   2805 C CA  . LEU B 2 128 ? 93.570  121.159 133.645 1.00 61.24  ?  122 LEU B CA  1 
ATOM   2806 C C   . LEU B 2 128 ? 93.140  122.577 133.991 1.00 61.24  ?  122 LEU B C   1 
ATOM   2807 O O   . LEU B 2 128 ? 93.756  123.196 134.866 1.00 61.24  ?  122 LEU B O   1 
ATOM   2808 C CB  . LEU B 2 128 ? 94.895  121.199 132.881 1.00 61.24  ?  122 LEU B CB  1 
ATOM   2809 C CG  . LEU B 2 128 ? 95.453  119.848 132.427 1.00 61.24  ?  122 LEU B CG  1 
ATOM   2810 C CD1 . LEU B 2 128 ? 96.777  120.037 131.707 1.00 61.24  ?  122 LEU B CD1 1 
ATOM   2811 C CD2 . LEU B 2 128 ? 95.614  118.899 133.604 1.00 61.24  ?  122 LEU B CD2 1 
ATOM   2812 N N   . ASP B 2 129 ? 92.109  123.109 133.330 1.00 61.76  ?  123 ASP B N   1 
ATOM   2813 C CA  . ASP B 2 129 ? 91.649  124.460 133.631 1.00 61.76  ?  123 ASP B CA  1 
ATOM   2814 C C   . ASP B 2 129 ? 90.994  124.553 135.003 1.00 61.76  ?  123 ASP B C   1 
ATOM   2815 O O   . ASP B 2 129 ? 90.853  125.660 135.533 1.00 61.76  ?  123 ASP B O   1 
ATOM   2816 C CB  . ASP B 2 129 ? 90.668  124.928 132.555 1.00 61.76  ?  123 ASP B CB  1 
ATOM   2817 C CG  . ASP B 2 129 ? 90.341  126.406 132.664 1.00 61.76  ?  123 ASP B CG  1 
ATOM   2818 O OD1 . ASP B 2 129 ? 91.023  127.115 133.433 1.00 61.76  ?  123 ASP B OD1 1 
ATOM   2819 O OD2 . ASP B 2 129 ? 89.399  126.858 131.980 1.00 61.76  ?  123 ASP B OD2 1 
ATOM   2820 N N   . ASN B 2 130 ? 90.595  123.424 135.588 1.00 61.58  ?  124 ASN B N   1 
ATOM   2821 C CA  . ASN B 2 130 ? 89.942  123.387 136.894 1.00 61.58  ?  124 ASN B CA  1 
ATOM   2822 C C   . ASN B 2 130 ? 88.588  124.088 136.880 1.00 61.58  ?  124 ASN B C   1 
ATOM   2823 O O   . ASN B 2 130 ? 88.072  124.469 137.936 1.00 61.58  ?  124 ASN B O   1 
ATOM   2824 C CB  . ASN B 2 130 ? 90.837  123.999 137.977 1.00 61.58  ?  124 ASN B CB  1 
ATOM   2825 C CG  . ASN B 2 130 ? 92.196  123.333 138.057 1.00 61.58  ?  124 ASN B CG  1 
ATOM   2826 O OD1 . ASN B 2 130 ? 92.594  122.600 137.152 1.00 61.58  ?  124 ASN B OD1 1 
ATOM   2827 N ND2 . ASN B 2 130 ? 92.916  123.585 139.144 1.00 61.58  ?  124 ASN B ND2 1 
ATOM   2828 N N   . ILE B 2 131 ? 88.002  124.268 135.699 1.00 59.64  ?  125 ILE B N   1 
ATOM   2829 C CA  . ILE B 2 131 ? 86.709  124.925 135.542 1.00 59.64  ?  125 ILE B CA  1 
ATOM   2830 C C   . ILE B 2 131 ? 85.845  124.039 134.657 1.00 59.64  ?  125 ILE B C   1 
ATOM   2831 O O   . ILE B 2 131 ? 86.154  123.849 133.474 1.00 59.64  ?  125 ILE B O   1 
ATOM   2832 C CB  . ILE B 2 131 ? 86.845  126.333 134.936 1.00 59.64  ?  125 ILE B CB  1 
ATOM   2833 C CG1 . ILE B 2 131 ? 87.828  127.170 135.760 1.00 59.64  ?  125 ILE B CG1 1 
ATOM   2834 C CG2 . ILE B 2 131 ? 85.487  127.025 134.875 1.00 59.64  ?  125 ILE B CG2 1 
ATOM   2835 C CD1 . ILE B 2 131 ? 88.051  128.568 135.219 1.00 59.64  ?  125 ILE B CD1 1 
ATOM   2836 N N   . CYS B 2 132 ? 84.769  123.501 135.224 1.00 59.33  ?  126 CYS B N   1 
ATOM   2837 C CA  . CYS B 2 132 ? 83.858  122.644 134.476 1.00 59.33  ?  126 CYS B CA  1 
ATOM   2838 C C   . CYS B 2 132 ? 82.926  123.509 133.637 1.00 59.33  ?  126 CYS B C   1 
ATOM   2839 O O   . CYS B 2 132 ? 82.179  124.334 134.177 1.00 59.33  ?  126 CYS B O   1 
ATOM   2840 C CB  . CYS B 2 132 ? 83.062  121.754 135.428 1.00 59.33  ?  126 CYS B CB  1 
ATOM   2841 S SG  . CYS B 2 132 ? 81.939  120.603 134.602 1.00 59.33  ?  126 CYS B SG  1 
ATOM   2842 N N   . SER B 2 133 ? 82.974  123.324 132.321 1.00 58.65  ?  127 SER B N   1 
ATOM   2843 C CA  . SER B 2 133 ? 82.171  124.097 131.382 1.00 58.65  ?  127 SER B CA  1 
ATOM   2844 C C   . SER B 2 133 ? 81.076  123.202 130.818 1.00 58.65  ?  127 SER B C   1 
ATOM   2845 O O   . SER B 2 133 ? 81.368  122.178 130.192 1.00 58.65  ?  127 SER B O   1 
ATOM   2846 C CB  . SER B 2 133 ? 83.039  124.660 130.257 1.00 58.65  ?  127 SER B CB  1 
ATOM   2847 O OG  . SER B 2 133 ? 84.046  125.515 130.770 1.00 58.65  ?  127 SER B OG  1 
ATOM   2848 N N   . ILE B 2 134 ? 79.824  123.585 131.050 1.00 57.46  ?  128 ILE B N   1 
ATOM   2849 C CA  . ILE B 2 134 ? 78.660  122.891 130.516 1.00 57.46  ?  128 ILE B CA  1 
ATOM   2850 C C   . ILE B 2 134 ? 78.042  123.789 129.455 1.00 57.46  ?  128 ILE B C   1 
ATOM   2851 O O   . ILE B 2 134 ? 77.606  124.909 129.755 1.00 57.46  ?  128 ILE B O   1 
ATOM   2852 C CB  . ILE B 2 134 ? 77.640  122.553 131.616 1.00 57.46  ?  128 ILE B CB  1 
ATOM   2853 C CG1 . ILE B 2 134 ? 78.251  121.598 132.646 1.00 57.46  ?  128 ILE B CG1 1 
ATOM   2854 C CG2 . ILE B 2 134 ? 76.385  121.938 131.008 1.00 57.46  ?  128 ILE B CG2 1 
ATOM   2855 C CD1 . ILE B 2 134 ? 79.164  122.269 133.653 1.00 57.46  ?  128 ILE B CD1 1 
ATOM   2856 N N   . TYR B 2 135 ? 78.020  123.302 128.218 1.00 58.41  ?  129 TYR B N   1 
ATOM   2857 C CA  . TYR B 2 135 ? 77.430  124.004 127.090 1.00 58.41  ?  129 TYR B CA  1 
ATOM   2858 C C   . TYR B 2 135 ? 76.057  123.425 126.778 1.00 58.41  ?  129 TYR B C   1 
ATOM   2859 O O   . TYR B 2 135 ? 75.775  122.257 127.061 1.00 58.41  ?  129 TYR B O   1 
ATOM   2860 C CB  . TYR B 2 135 ? 78.324  123.899 125.852 1.00 58.41  ?  129 TYR B CB  1 
ATOM   2861 C CG  . TYR B 2 135 ? 79.715  124.462 126.037 1.00 58.41  ?  129 TYR B CG  1 
ATOM   2862 C CD1 . TYR B 2 135 ? 80.705  123.725 126.673 1.00 58.41  ?  129 TYR B CD1 1 
ATOM   2863 C CD2 . TYR B 2 135 ? 80.040  125.726 125.566 1.00 58.41  ?  129 TYR B CD2 1 
ATOM   2864 C CE1 . TYR B 2 135 ? 81.978  124.235 126.841 1.00 58.41  ?  129 TYR B CE1 1 
ATOM   2865 C CE2 . TYR B 2 135 ? 81.311  126.244 125.729 1.00 58.41  ?  129 TYR B CE2 1 
ATOM   2866 C CZ  . TYR B 2 135 ? 82.276  125.494 126.367 1.00 58.41  ?  129 TYR B CZ  1 
ATOM   2867 O OH  . TYR B 2 135 ? 83.543  126.006 126.531 1.00 58.41  ?  129 TYR B OH  1 
ATOM   2868 N N   . ASN B 2 136 ? 75.203  124.256 126.187 1.00 59.05  ?  130 ASN B N   1 
ATOM   2869 C CA  . ASN B 2 136 ? 73.864  123.854 125.785 1.00 59.05  ?  130 ASN B CA  1 
ATOM   2870 C C   . ASN B 2 136 ? 73.813  123.680 124.272 1.00 59.05  ?  130 ASN B C   1 
ATOM   2871 O O   . ASN B 2 136 ? 74.359  124.497 123.524 1.00 59.05  ?  130 ASN B O   1 
ATOM   2872 C CB  . ASN B 2 136 ? 72.828  124.889 126.231 1.00 59.05  ?  130 ASN B CB  1 
ATOM   2873 C CG  . ASN B 2 136 ? 71.400  124.419 126.020 1.00 59.05  ?  130 ASN B CG  1 
ATOM   2874 O OD1 . ASN B 2 136 ? 71.121  123.612 125.133 1.00 59.05  ?  130 ASN B OD1 1 
ATOM   2875 N ND2 . ASN B 2 136 ? 70.486  124.926 126.840 1.00 59.05  ?  130 ASN B ND2 1 
ATOM   2876 N N   . LEU B 2 137 ? 73.153  122.609 123.828 1.00 58.60  ?  131 LEU B N   1 
ATOM   2877 C CA  . LEU B 2 137 ? 73.062  122.292 122.410 1.00 58.60  ?  131 LEU B CA  1 
ATOM   2878 C C   . LEU B 2 137 ? 71.753  122.737 121.773 1.00 58.60  ?  131 LEU B C   1 
ATOM   2879 O O   . LEU B 2 137 ? 71.712  122.926 120.552 1.00 58.60  ?  131 LEU B O   1 
ATOM   2880 C CB  . LEU B 2 137 ? 73.225  120.782 122.194 1.00 58.60  ?  131 LEU B CB  1 
ATOM   2881 C CG  . LEU B 2 137 ? 74.529  120.161 122.700 1.00 58.60  ?  131 LEU B CG  1 
ATOM   2882 C CD1 . LEU B 2 137 ? 74.518  118.658 122.474 1.00 58.60  ?  131 LEU B CD1 1 
ATOM   2883 C CD2 . LEU B 2 137 ? 75.736  120.796 122.026 1.00 58.60  ?  131 LEU B CD2 1 
ATOM   2884 N N   . LYS B 2 138 ? 70.692  122.909 122.559 1.00 59.29  ?  132 LYS B N   1 
ATOM   2885 C CA  . LYS B 2 138 ? 69.379  123.297 122.046 1.00 59.29  ?  132 LYS B CA  1 
ATOM   2886 C C   . LYS B 2 138 ? 69.086  124.769 122.301 1.00 59.29  ?  132 LYS B C   1 
ATOM   2887 O O   . LYS B 2 138 ? 67.941  125.149 122.564 1.00 59.29  ?  132 LYS B O   1 
ATOM   2888 C CB  . LYS B 2 138 ? 68.293  122.421 122.665 1.00 59.29  ?  132 LYS B CB  1 
ATOM   2889 C CG  . LYS B 2 138 ? 68.506  120.925 122.471 1.00 59.29  ?  132 LYS B CG  1 
ATOM   2890 C CD  . LYS B 2 138 ? 68.501  120.537 120.999 1.00 59.29  ?  132 LYS B CD  1 
ATOM   2891 C CE  . LYS B 2 138 ? 68.692  119.039 120.817 1.00 59.29  ?  132 LYS B CE  1 
ATOM   2892 N NZ  . LYS B 2 138 ? 67.605  118.249 121.458 1.00 59.29  1  132 LYS B NZ  1 
ATOM   2893 N N   . THR B 2 139 ? 70.105  125.620 122.229 1.00 62.17  ?  133 THR B N   1 
ATOM   2894 C CA  . THR B 2 139 ? 69.906  127.046 122.438 1.00 62.17  ?  133 THR B CA  1 
ATOM   2895 C C   . THR B 2 139 ? 69.078  127.644 121.307 1.00 62.17  ?  133 THR B C   1 
ATOM   2896 O O   . THR B 2 139 ? 69.177  127.233 120.147 1.00 62.17  ?  133 THR B O   1 
ATOM   2897 C CB  . THR B 2 139 ? 71.251  127.768 122.529 1.00 62.17  ?  133 THR B CB  1 
ATOM   2898 O OG1 . THR B 2 139 ? 71.990  127.565 121.318 1.00 62.17  ?  133 THR B OG1 1 
ATOM   2899 C CG2 . THR B 2 139 ? 72.059  127.250 123.707 1.00 62.17  ?  133 THR B CG2 1 
ATOM   2900 N N   . ARG B 2 140 ? 68.249  128.629 121.659 1.00 65.70  ?  134 ARG B N   1 
ATOM   2901 C CA  . ARG B 2 140 ? 67.448  129.311 120.649 1.00 65.70  ?  134 ARG B CA  1 
ATOM   2902 C C   . ARG B 2 140 ? 68.326  129.975 119.596 1.00 65.70  ?  134 ARG B C   1 
ATOM   2903 O O   . ARG B 2 140 ? 67.904  130.133 118.445 1.00 65.70  ?  134 ARG B O   1 
ATOM   2904 C CB  . ARG B 2 140 ? 66.539  130.347 121.312 1.00 65.70  ?  134 ARG B CB  1 
ATOM   2905 C CG  . ARG B 2 140 ? 67.286  131.442 122.059 1.00 65.70  ?  134 ARG B CG  1 
ATOM   2906 C CD  . ARG B 2 140 ? 66.327  132.428 122.705 1.00 65.70  ?  134 ARG B CD  1 
ATOM   2907 N NE  . ARG B 2 140 ? 67.030  133.514 123.383 1.00 65.70  ?  134 ARG B NE  1 
ATOM   2908 C CZ  . ARG B 2 140 ? 67.470  134.617 122.784 1.00 65.70  ?  134 ARG B CZ  1 
ATOM   2909 N NH1 . ARG B 2 140 ? 67.287  134.796 121.482 1.00 65.70  1  134 ARG B NH1 1 
ATOM   2910 N NH2 . ARG B 2 140 ? 68.098  135.547 123.491 1.00 65.70  ?  134 ARG B NH2 1 
ATOM   2911 N N   . GLU B 2 141 ? 69.543  130.369 119.968 1.00 63.97  ?  135 GLU B N   1 
ATOM   2912 C CA  . GLU B 2 141 ? 70.470  131.002 119.040 1.00 63.97  ?  135 GLU B CA  1 
ATOM   2913 C C   . GLU B 2 141 ? 71.158  130.006 118.117 1.00 63.97  ?  135 GLU B C   1 
ATOM   2914 O O   . GLU B 2 141 ? 71.906  130.427 117.228 1.00 63.97  ?  135 GLU B O   1 
ATOM   2915 C CB  . GLU B 2 141 ? 71.527  131.792 119.816 1.00 63.97  ?  135 GLU B CB  1 
ATOM   2916 C CG  . GLU B 2 141 ? 70.953  132.824 120.774 1.00 63.97  ?  135 GLU B CG  1 
ATOM   2917 C CD  . GLU B 2 141 ? 72.029  133.601 121.507 1.00 63.97  ?  135 GLU B CD  1 
ATOM   2918 O OE1 . GLU B 2 141 ? 73.225  133.338 121.262 1.00 63.97  ?  135 GLU B OE1 1 
ATOM   2919 O OE2 . GLU B 2 141 ? 71.678  134.474 122.328 1.00 63.97  ?  135 GLU B OE2 1 
ATOM   2920 N N   . GLY B 2 142 ? 70.934  128.712 118.301 1.00 62.12  ?  136 GLY B N   1 
ATOM   2921 C CA  . GLY B 2 142 ? 71.566  127.702 117.454 1.00 62.12  ?  136 GLY B CA  1 
ATOM   2922 C C   . GLY B 2 142 ? 73.019  127.435 117.764 1.00 62.12  ?  136 GLY B C   1 
ATOM   2923 O O   . GLY B 2 142 ? 73.393  126.293 118.047 1.00 62.12  ?  136 GLY B O   1 
ATOM   2924 N N   . ASN B 2 143 ? 73.858  128.467 117.717 1.00 62.64  ?  137 ASN B N   1 
ATOM   2925 C CA  . ASN B 2 143 ? 75.269  128.292 118.027 1.00 62.64  ?  137 ASN B CA  1 
ATOM   2926 C C   . ASN B 2 143 ? 75.444  127.842 119.474 1.00 62.64  ?  137 ASN B C   1 
ATOM   2927 O O   . ASN B 2 143 ? 74.594  128.088 120.334 1.00 62.64  ?  137 ASN B O   1 
ATOM   2928 C CB  . ASN B 2 143 ? 76.035  129.594 117.784 1.00 62.64  ?  137 ASN B CB  1 
ATOM   2929 C CG  . ASN B 2 143 ? 75.443  130.772 118.536 1.00 62.64  ?  137 ASN B CG  1 
ATOM   2930 O OD1 . ASN B 2 143 ? 74.655  130.599 119.466 1.00 62.64  ?  137 ASN B OD1 1 
ATOM   2931 N ND2 . ASN B 2 143 ? 75.822  131.979 118.135 1.00 62.64  ?  137 ASN B ND2 1 
ATOM   2932 N N   . VAL B 2 144 ? 76.562  127.174 119.736 1.00 60.27  ?  138 VAL B N   1 
ATOM   2933 C CA  . VAL B 2 144 ? 76.853  126.670 121.073 1.00 60.27  ?  138 VAL B CA  1 
ATOM   2934 C C   . VAL B 2 144 ? 77.261  127.835 121.963 1.00 60.27  ?  138 VAL B C   1 
ATOM   2935 O O   . VAL B 2 144 ? 78.140  128.629 121.607 1.00 60.27  ?  138 VAL B O   1 
ATOM   2936 C CB  . VAL B 2 144 ? 77.951  125.596 121.022 1.00 60.27  ?  138 VAL B CB  1 
ATOM   2937 C CG1 . VAL B 2 144 ? 78.271  125.096 122.423 1.00 60.27  ?  138 VAL B CG1 1 
ATOM   2938 C CG2 . VAL B 2 144 ? 77.524  124.444 120.122 1.00 60.27  ?  138 VAL B CG2 1 
ATOM   2939 N N   . ARG B 2 145 ? 76.622  127.939 123.126 1.00 62.09  ?  139 ARG B N   1 
ATOM   2940 C CA  . ARG B 2 145 ? 76.873  129.009 124.077 1.00 62.09  ?  139 ARG B CA  1 
ATOM   2941 C C   . ARG B 2 145 ? 77.359  128.421 125.395 1.00 62.09  ?  139 ARG B C   1 
ATOM   2942 O O   . ARG B 2 145 ? 77.047  127.276 125.737 1.00 62.09  ?  139 ARG B O   1 
ATOM   2943 C CB  . ARG B 2 145 ? 75.608  129.846 124.311 1.00 62.09  ?  139 ARG B CB  1 
ATOM   2944 C CG  . ARG B 2 145 ? 75.802  131.037 125.237 1.00 62.09  ?  139 ARG B CG  1 
ATOM   2945 C CD  . ARG B 2 145 ? 74.516  131.833 125.392 1.00 62.09  ?  139 ARG B CD  1 
ATOM   2946 N NE  . ARG B 2 145 ? 73.442  131.031 125.971 1.00 62.09  ?  139 ARG B NE  1 
ATOM   2947 C CZ  . ARG B 2 145 ? 72.213  131.480 126.208 1.00 62.09  ?  139 ARG B CZ  1 
ATOM   2948 N NH1 . ARG B 2 145 ? 71.890  132.734 125.918 1.00 62.09  1  139 ARG B NH1 1 
ATOM   2949 N NH2 . ARG B 2 145 ? 71.304  130.673 126.738 1.00 62.09  ?  139 ARG B NH2 1 
ATOM   2950 N N   . VAL B 2 146 ? 78.129  129.218 126.135 1.00 59.12  ?  140 VAL B N   1 
ATOM   2951 C CA  . VAL B 2 146 ? 78.628  128.809 127.443 1.00 59.12  ?  140 VAL B CA  1 
ATOM   2952 C C   . VAL B 2 146 ? 77.482  128.882 128.441 1.00 59.12  ?  140 VAL B C   1 
ATOM   2953 O O   . VAL B 2 146 ? 77.147  129.963 128.940 1.00 59.12  ?  140 VAL B O   1 
ATOM   2954 C CB  . VAL B 2 146 ? 79.810  129.688 127.895 1.00 59.12  ?  140 VAL B CB  1 
ATOM   2955 C CG1 . VAL B 2 146 ? 80.327  129.229 129.250 1.00 59.12  ?  140 VAL B CG1 1 
ATOM   2956 C CG2 . VAL B 2 146 ? 80.924  129.665 126.858 1.00 59.12  ?  140 VAL B CG2 1 
ATOM   2957 N N   . SER B 2 147 ? 76.871  127.734 128.741 1.00 59.09  ?  141 SER B N   1 
ATOM   2958 C CA  . SER B 2 147 ? 75.725  127.727 129.644 1.00 59.09  ?  141 SER B CA  1 
ATOM   2959 C C   . SER B 2 147 ? 76.162  127.959 131.085 1.00 59.09  ?  141 SER B C   1 
ATOM   2960 O O   . SER B 2 147 ? 75.628  128.839 131.770 1.00 59.09  ?  141 SER B O   1 
ATOM   2961 C CB  . SER B 2 147 ? 74.960  126.409 129.515 1.00 59.09  ?  141 SER B CB  1 
ATOM   2962 O OG  . SER B 2 147 ? 75.698  125.328 130.056 1.00 59.09  ?  141 SER B OG  1 
ATOM   2963 N N   . ARG B 2 148 ? 77.136  127.185 131.563 1.00 59.90  ?  142 ARG B N   1 
ATOM   2964 C CA  . ARG B 2 148 ? 77.599  127.322 132.944 1.00 59.90  ?  142 ARG B CA  1 
ATOM   2965 C C   . ARG B 2 148 ? 79.075  126.955 133.013 1.00 59.90  ?  142 ARG B C   1 
ATOM   2966 O O   . ARG B 2 148 ? 79.432  125.789 132.832 1.00 59.90  ?  142 ARG B O   1 
ATOM   2967 C CB  . ARG B 2 148 ? 76.778  126.445 133.887 1.00 59.90  ?  142 ARG B CB  1 
ATOM   2968 C CG  . ARG B 2 148 ? 75.407  127.004 134.243 1.00 59.90  ?  142 ARG B CG  1 
ATOM   2969 C CD  . ARG B 2 148 ? 75.516  128.254 135.107 1.00 59.90  ?  142 ARG B CD  1 
ATOM   2970 N NE  . ARG B 2 148 ? 74.214  128.703 135.594 1.00 59.90  ?  142 ARG B NE  1 
ATOM   2971 C CZ  . ARG B 2 148 ? 73.385  129.494 134.916 1.00 59.90  ?  142 ARG B CZ  1 
ATOM   2972 N NH1 . ARG B 2 148 ? 73.710  129.933 133.707 1.00 59.90  1  142 ARG B NH1 1 
ATOM   2973 N NH2 . ARG B 2 148 ? 72.224  129.845 135.450 1.00 59.90  ?  142 ARG B NH2 1 
ATOM   2974 N N   . GLU B 2 149 ? 79.923  127.941 133.285 1.00 60.84  ?  143 GLU B N   1 
ATOM   2975 C CA  . GLU B 2 149 ? 81.357  127.729 133.482 1.00 60.84  ?  143 GLU B CA  1 
ATOM   2976 C C   . GLU B 2 149 ? 81.629  127.841 134.981 1.00 60.84  ?  143 GLU B C   1 
ATOM   2977 O O   . GLU B 2 149 ? 81.976  128.910 135.487 1.00 60.84  ?  143 GLU B O   1 
ATOM   2978 C CB  . GLU B 2 149 ? 82.184  128.731 132.672 1.00 60.84  ?  143 GLU B CB  1 
ATOM   2979 C CG  . GLU B 2 149 ? 81.733  130.180 132.802 1.00 60.84  ?  143 GLU B CG  1 
ATOM   2980 C CD  . GLU B 2 149 ? 82.599  131.132 132.000 1.00 60.84  ?  143 GLU B CD  1 
ATOM   2981 O OE1 . GLU B 2 149 ? 83.556  130.663 131.349 1.00 60.84  ?  143 GLU B OE1 1 
ATOM   2982 O OE2 . GLU B 2 149 ? 82.323  132.350 132.022 1.00 60.84  ?  143 GLU B OE2 1 
ATOM   2983 N N   . LEU B 2 150 ? 81.472  126.726 135.690 1.00 58.08  ?  144 LEU B N   1 
ATOM   2984 C CA  . LEU B 2 150 ? 81.586  126.719 137.142 1.00 58.08  ?  144 LEU B CA  1 
ATOM   2985 C C   . LEU B 2 150 ? 83.012  126.389 137.562 1.00 58.08  ?  144 LEU B C   1 
ATOM   2986 O O   . LEU B 2 150 ? 83.706  125.612 136.899 1.00 58.08  ?  144 LEU B O   1 
ATOM   2987 C CB  . LEU B 2 150 ? 80.607  125.714 137.754 1.00 58.08  ?  144 LEU B CB  1 
ATOM   2988 C CG  . LEU B 2 150 ? 80.796  124.232 137.412 1.00 58.08  ?  144 LEU B CG  1 
ATOM   2989 C CD1 . LEU B 2 150 ? 81.843  123.573 138.307 1.00 58.08  ?  144 LEU B CD1 1 
ATOM   2990 C CD2 . LEU B 2 150 ? 79.468  123.494 137.508 1.00 58.08  ?  144 LEU B CD2 1 
ATOM   2991 N N   . ALA B 2 151 ? 83.445  126.990 138.668 1.00 58.41  ?  145 ALA B N   1 
ATOM   2992 C CA  . ALA B 2 151 ? 84.779  126.790 139.209 1.00 58.41  ?  145 ALA B CA  1 
ATOM   2993 C C   . ALA B 2 151 ? 84.690  126.609 140.718 1.00 58.41  ?  145 ALA B C   1 
ATOM   2994 O O   . ALA B 2 151 ? 83.625  126.754 141.324 1.00 58.41  ?  145 ALA B O   1 
ATOM   2995 C CB  . ALA B 2 151 ? 85.704  127.966 138.867 1.00 58.41  ?  145 ALA B CB  1 
ATOM   2996 N N   . GLY B 2 152 ? 85.831  126.289 141.325 1.00 59.11  ?  146 GLY B N   1 
ATOM   2997 C CA  . GLY B 2 152 ? 85.899  126.094 142.760 1.00 59.11  ?  146 GLY B CA  1 
ATOM   2998 C C   . GLY B 2 152 ? 86.821  124.962 143.162 1.00 59.11  ?  146 GLY B C   1 
ATOM   2999 O O   . GLY B 2 152 ? 87.210  124.855 144.329 1.00 59.11  ?  146 GLY B O   1 
ATOM   3000 N N   . HIS B 2 153 ? 87.178  124.109 142.205 1.00 60.35  ?  147 HIS B N   1 
ATOM   3001 C CA  . HIS B 2 153 ? 88.065  122.982 142.461 1.00 60.35  ?  147 HIS B CA  1 
ATOM   3002 C C   . HIS B 2 153 ? 89.514  123.402 142.254 1.00 60.35  ?  147 HIS B C   1 
ATOM   3003 O O   . HIS B 2 153 ? 89.851  124.015 141.236 1.00 60.35  ?  147 HIS B O   1 
ATOM   3004 C CB  . HIS B 2 153 ? 87.722  121.808 141.544 1.00 60.35  ?  147 HIS B CB  1 
ATOM   3005 C CG  . HIS B 2 153 ? 86.481  121.071 141.941 1.00 60.35  ?  147 HIS B CG  1 
ATOM   3006 N ND1 . HIS B 2 153 ? 86.038  121.007 143.245 1.00 60.35  ?  147 HIS B ND1 1 
ATOM   3007 C CD2 . HIS B 2 153 ? 85.590  120.365 141.206 1.00 60.35  ?  147 HIS B CD2 1 
ATOM   3008 C CE1 . HIS B 2 153 ? 84.928  120.292 143.295 1.00 60.35  ?  147 HIS B CE1 1 
ATOM   3009 N NE2 . HIS B 2 153 ? 84.634  119.891 142.072 1.00 60.35  ?  147 HIS B NE2 1 
ATOM   3010 N N   . THR B 2 154 ? 90.363  123.073 143.223 1.00 62.10  ?  148 THR B N   1 
ATOM   3011 C CA  . THR B 2 154 ? 91.794  123.369 143.144 1.00 62.10  ?  148 THR B CA  1 
ATOM   3012 C C   . THR B 2 154 ? 92.569  122.197 142.548 1.00 62.10  ?  148 THR B C   1 
ATOM   3013 O O   . THR B 2 154 ? 93.526  121.694 143.134 1.00 62.10  ?  148 THR B O   1 
ATOM   3014 C CB  . THR B 2 154 ? 92.326  123.727 144.527 1.00 62.10  ?  148 THR B CB  1 
ATOM   3015 O OG1 . THR B 2 154 ? 92.093  122.638 145.430 1.00 62.10  ?  148 THR B OG1 1 
ATOM   3016 C CG2 . THR B 2 154 ? 91.640  124.979 145.057 1.00 62.10  ?  148 THR B CG2 1 
ATOM   3017 N N   . GLY B 2 155 ? 92.153  121.756 141.368 1.00 62.04  ?  149 GLY B N   1 
ATOM   3018 C CA  . GLY B 2 155 ? 92.811  120.641 140.716 1.00 62.04  ?  149 GLY B CA  1 
ATOM   3019 C C   . GLY B 2 155 ? 92.171  120.362 139.374 1.00 62.04  ?  149 GLY B C   1 
ATOM   3020 O O   . GLY B 2 155 ? 91.053  120.803 139.087 1.00 62.04  ?  149 GLY B O   1 
ATOM   3021 N N   . TYR B 2 156 ? 92.906  119.614 138.556 1.00 61.27  ?  150 TYR B N   1 
ATOM   3022 C CA  . TYR B 2 156 ? 92.432  119.274 137.222 1.00 61.27  ?  150 TYR B CA  1 
ATOM   3023 C C   . TYR B 2 156 ? 91.197  118.385 137.299 1.00 61.27  ?  150 TYR B C   1 
ATOM   3024 O O   . TYR B 2 156 ? 91.100  117.499 138.153 1.00 61.27  ?  150 TYR B O   1 
ATOM   3025 C CB  . TYR B 2 156 ? 93.535  118.569 136.431 1.00 61.27  ?  150 TYR B CB  1 
ATOM   3026 C CG  . TYR B 2 156 ? 94.033  117.291 137.071 1.00 61.27  ?  150 TYR B CG  1 
ATOM   3027 C CD1 . TYR B 2 156 ? 95.117  117.302 137.940 1.00 61.27  ?  150 TYR B CD1 1 
ATOM   3028 C CD2 . TYR B 2 156 ? 93.421  116.073 136.804 1.00 61.27  ?  150 TYR B CD2 1 
ATOM   3029 C CE1 . TYR B 2 156 ? 95.575  116.137 138.526 1.00 61.27  ?  150 TYR B CE1 1 
ATOM   3030 C CE2 . TYR B 2 156 ? 93.873  114.903 137.386 1.00 61.27  ?  150 TYR B CE2 1 
ATOM   3031 C CZ  . TYR B 2 156 ? 94.950  114.941 138.245 1.00 61.27  ?  150 TYR B CZ  1 
ATOM   3032 O OH  . TYR B 2 156 ? 95.403  113.779 138.826 1.00 61.27  ?  150 TYR B OH  1 
ATOM   3033 N N   . LEU B 2 157 ? 90.250  118.627 136.395 1.00 60.27  ?  151 LEU B N   1 
ATOM   3034 C CA  . LEU B 2 157 ? 89.042  117.816 136.321 1.00 60.27  ?  151 LEU B CA  1 
ATOM   3035 C C   . LEU B 2 157 ? 89.330  116.534 135.551 1.00 60.27  ?  151 LEU B C   1 
ATOM   3036 O O   . LEU B 2 157 ? 89.932  116.568 134.474 1.00 60.27  ?  151 LEU B O   1 
ATOM   3037 C CB  . LEU B 2 157 ? 87.915  118.600 135.649 1.00 60.27  ?  151 LEU B CB  1 
ATOM   3038 C CG  . LEU B 2 157 ? 87.539  119.926 136.315 1.00 60.27  ?  151 LEU B CG  1 
ATOM   3039 C CD1 . LEU B 2 157 ? 86.435  120.624 135.538 1.00 60.27  ?  151 LEU B CD1 1 
ATOM   3040 C CD2 . LEU B 2 157 ? 87.121  119.707 137.761 1.00 60.27  ?  151 LEU B CD2 1 
ATOM   3041 N N   . SER B 2 158 ? 88.894  115.404 136.103 1.00 61.00  ?  152 SER B N   1 
ATOM   3042 C CA  . SER B 2 158 ? 89.181  114.089 135.540 1.00 61.00  ?  152 SER B CA  1 
ATOM   3043 C C   . SER B 2 158 ? 87.997  113.462 134.823 1.00 61.00  ?  152 SER B C   1 
ATOM   3044 O O   . SER B 2 158 ? 88.180  112.837 133.776 1.00 61.00  ?  152 SER B O   1 
ATOM   3045 C CB  . SER B 2 158 ? 89.654  113.139 136.645 1.00 61.00  ?  152 SER B CB  1 
ATOM   3046 O OG  . SER B 2 158 ? 88.655  112.970 137.636 1.00 61.00  ?  152 SER B OG  1 
ATOM   3047 N N   . CYS B 2 159 ? 86.785  113.605 135.356 1.00 59.59  ?  153 CYS B N   1 
ATOM   3048 C CA  . CYS B 2 159 ? 85.611  113.002 134.744 1.00 59.59  ?  153 CYS B CA  1 
ATOM   3049 C C   . CYS B 2 159 ? 84.380  113.819 135.105 1.00 59.59  ?  153 CYS B C   1 
ATOM   3050 O O   . CYS B 2 159 ? 84.349  114.521 136.119 1.00 59.59  ?  153 CYS B O   1 
ATOM   3051 C CB  . CYS B 2 159 ? 85.432  111.545 135.186 1.00 59.59  ?  153 CYS B CB  1 
ATOM   3052 S SG  . CYS B 2 159 ? 84.026  110.710 134.415 1.00 59.59  ?  153 CYS B SG  1 
ATOM   3053 N N   . CYS B 2 160 ? 83.360  113.717 134.254 1.00 58.47  ?  154 CYS B N   1 
ATOM   3054 C CA  . CYS B 2 160 ? 82.102  114.421 134.450 1.00 58.47  ?  154 CYS B CA  1 
ATOM   3055 C C   . CYS B 2 160 ? 80.951  113.499 134.079 1.00 58.47  ?  154 CYS B C   1 
ATOM   3056 O O   . CYS B 2 160 ? 81.054  112.719 133.128 1.00 58.47  ?  154 CYS B O   1 
ATOM   3057 C CB  . CYS B 2 160 ? 82.040  115.702 133.607 1.00 58.47  ?  154 CYS B CB  1 
ATOM   3058 S SG  . CYS B 2 160 ? 83.368  116.879 133.950 1.00 58.47  ?  154 CYS B SG  1 
ATOM   3059 N N   . ARG B 2 161 ? 79.860  113.590 134.836 1.00 57.86  ?  155 ARG B N   1 
ATOM   3060 C CA  . ARG B 2 161 ? 78.683  112.765 134.596 1.00 57.86  ?  155 ARG B CA  1 
ATOM   3061 C C   . ARG B 2 161 ? 77.440  113.553 134.977 1.00 57.86  ?  155 ARG B C   1 
ATOM   3062 O O   . ARG B 2 161 ? 77.398  114.168 136.046 1.00 57.86  ?  155 ARG B O   1 
ATOM   3063 C CB  . ARG B 2 161 ? 78.750  111.458 135.396 1.00 57.86  ?  155 ARG B CB  1 
ATOM   3064 C CG  . ARG B 2 161 ? 79.829  110.487 134.935 1.00 57.86  ?  155 ARG B CG  1 
ATOM   3065 C CD  . ARG B 2 161 ? 79.530  109.930 133.551 1.00 57.86  ?  155 ARG B CD  1 
ATOM   3066 N NE  . ARG B 2 161 ? 80.513  108.932 133.136 1.00 57.86  ?  155 ARG B NE  1 
ATOM   3067 C CZ  . ARG B 2 161 ? 81.661  109.210 132.525 1.00 57.86  ?  155 ARG B CZ  1 
ATOM   3068 N NH1 . ARG B 2 161 ? 81.992  110.466 132.250 1.00 57.86  1  155 ARG B NH1 1 
ATOM   3069 N NH2 . ARG B 2 161 ? 82.485  108.228 132.188 1.00 57.86  ?  155 ARG B NH2 1 
ATOM   3070 N N   . PHE B 2 162 ? 76.438  113.533 134.102 1.00 56.80  ?  156 PHE B N   1 
ATOM   3071 C CA  . PHE B 2 162 ? 75.184  114.234 134.341 1.00 56.80  ?  156 PHE B CA  1 
ATOM   3072 C C   . PHE B 2 162 ? 74.219  113.339 135.108 1.00 56.80  ?  156 PHE B C   1 
ATOM   3073 O O   . PHE B 2 162 ? 74.047  112.164 134.768 1.00 56.80  ?  156 PHE B O   1 
ATOM   3074 C CB  . PHE B 2 162 ? 74.548  114.673 133.022 1.00 56.80  ?  156 PHE B CB  1 
ATOM   3075 C CG  . PHE B 2 162 ? 75.130  115.935 132.454 1.00 56.80  ?  156 PHE B CG  1 
ATOM   3076 C CD1 . PHE B 2 162 ? 74.645  117.172 132.844 1.00 56.80  ?  156 PHE B CD1 1 
ATOM   3077 C CD2 . PHE B 2 162 ? 76.155  115.885 131.525 1.00 56.80  ?  156 PHE B CD2 1 
ATOM   3078 C CE1 . PHE B 2 162 ? 75.174  118.335 132.322 1.00 56.80  ?  156 PHE B CE1 1 
ATOM   3079 C CE2 . PHE B 2 162 ? 76.689  117.046 131.000 1.00 56.80  ?  156 PHE B CE2 1 
ATOM   3080 C CZ  . PHE B 2 162 ? 76.197  118.272 131.399 1.00 56.80  ?  156 PHE B CZ  1 
ATOM   3081 N N   . LEU B 2 163 ? 73.593  113.900 136.142 1.00 60.20  ?  157 LEU B N   1 
ATOM   3082 C CA  . LEU B 2 163 ? 72.547  113.211 136.886 1.00 60.20  ?  157 LEU B CA  1 
ATOM   3083 C C   . LEU B 2 163 ? 71.148  113.638 136.471 1.00 60.20  ?  157 LEU B C   1 
ATOM   3084 O O   . LEU B 2 163 ? 70.206  112.849 136.602 1.00 60.20  ?  157 LEU B O   1 
ATOM   3085 C CB  . LEU B 2 163 ? 72.712  113.455 138.391 1.00 60.20  ?  157 LEU B CB  1 
ATOM   3086 C CG  . LEU B 2 163 ? 73.879  112.747 139.083 1.00 60.20  ?  157 LEU B CG  1 
ATOM   3087 C CD1 . LEU B 2 163 ? 75.218  113.280 138.600 1.00 60.20  ?  157 LEU B CD1 1 
ATOM   3088 C CD2 . LEU B 2 163 ? 73.759  112.888 140.592 1.00 60.20  ?  157 LEU B CD2 1 
ATOM   3089 N N   . ASP B 2 164 ? 70.993  114.858 135.978 1.00 60.90  ?  158 ASP B N   1 
ATOM   3090 C CA  . ASP B 2 164 ? 69.707  115.387 135.532 1.00 60.90  ?  158 ASP B CA  1 
ATOM   3091 C C   . ASP B 2 164 ? 69.991  116.664 134.747 1.00 60.90  ?  158 ASP B C   1 
ATOM   3092 O O   . ASP B 2 164 ? 71.151  117.009 134.492 1.00 60.90  ?  158 ASP B O   1 
ATOM   3093 C CB  . ASP B 2 164 ? 68.766  115.627 136.714 1.00 60.90  ?  158 ASP B CB  1 
ATOM   3094 C CG  . ASP B 2 164 ? 69.355  116.565 137.749 1.00 60.90  ?  158 ASP B CG  1 
ATOM   3095 O OD1 . ASP B 2 164 ? 69.484  117.772 137.456 1.00 60.90  ?  158 ASP B OD1 1 
ATOM   3096 O OD2 . ASP B 2 164 ? 69.689  116.095 138.856 1.00 60.90  ?  158 ASP B OD2 1 
ATOM   3097 N N   . ASP B 2 165 ? 68.930  117.370 134.361 1.00 60.41  ?  159 ASP B N   1 
ATOM   3098 C CA  . ASP B 2 165 ? 69.065  118.597 133.588 1.00 60.41  ?  159 ASP B CA  1 
ATOM   3099 C C   . ASP B 2 165 ? 69.458  119.798 134.439 1.00 60.41  ?  159 ASP B C   1 
ATOM   3100 O O   . ASP B 2 165 ? 69.544  120.909 133.905 1.00 60.41  ?  159 ASP B O   1 
ATOM   3101 C CB  . ASP B 2 165 ? 67.755  118.899 132.856 1.00 60.41  ?  159 ASP B CB  1 
ATOM   3102 C CG  . ASP B 2 165 ? 67.331  117.773 131.934 1.00 60.41  ?  159 ASP B CG  1 
ATOM   3103 O OD1 . ASP B 2 165 ? 68.033  116.742 131.894 1.00 60.41  ?  159 ASP B OD1 1 
ATOM   3104 O OD2 . ASP B 2 165 ? 66.296  117.920 131.251 1.00 60.41  ?  159 ASP B OD2 1 
ATOM   3105 N N   . ASN B 2 166 ? 69.697  119.609 135.739 1.00 61.34  ?  160 ASN B N   1 
ATOM   3106 C CA  . ASN B 2 166 ? 70.060  120.717 136.614 1.00 61.34  ?  160 ASN B CA  1 
ATOM   3107 C C   . ASN B 2 166 ? 71.222  120.414 137.550 1.00 61.34  ?  160 ASN B C   1 
ATOM   3108 O O   . ASN B 2 166 ? 71.734  121.350 138.172 1.00 61.34  ?  160 ASN B O   1 
ATOM   3109 C CB  . ASN B 2 166 ? 68.848  121.144 137.456 1.00 61.34  ?  160 ASN B CB  1 
ATOM   3110 C CG  . ASN B 2 166 ? 69.049  122.489 138.125 1.00 61.34  ?  160 ASN B CG  1 
ATOM   3111 O OD1 . ASN B 2 166 ? 69.786  123.340 137.626 1.00 61.34  ?  160 ASN B OD1 1 
ATOM   3112 N ND2 . ASN B 2 166 ? 68.392  122.689 139.261 1.00 61.34  ?  160 ASN B ND2 1 
ATOM   3113 N N   . GLN B 2 167 ? 71.658  119.162 137.677 1.00 59.45  ?  161 GLN B N   1 
ATOM   3114 C CA  . GLN B 2 167 ? 72.757  118.796 138.557 1.00 59.45  ?  161 GLN B CA  1 
ATOM   3115 C C   . GLN B 2 167 ? 73.779  117.978 137.782 1.00 59.45  ?  161 GLN B C   1 
ATOM   3116 O O   . GLN B 2 167 ? 73.440  117.278 136.824 1.00 59.45  ?  161 GLN B O   1 
ATOM   3117 C CB  . GLN B 2 167 ? 72.262  117.997 139.771 1.00 59.45  ?  161 GLN B CB  1 
ATOM   3118 C CG  . GLN B 2 167 ? 71.239  118.736 140.621 1.00 59.45  ?  161 GLN B CG  1 
ATOM   3119 C CD  . GLN B 2 167 ? 70.839  117.968 141.869 1.00 59.45  ?  161 GLN B CD  1 
ATOM   3120 O OE1 . GLN B 2 167 ? 70.640  118.556 142.932 1.00 59.45  ?  161 GLN B OE1 1 
ATOM   3121 N NE2 . GLN B 2 167 ? 70.712  116.651 141.744 1.00 59.45  ?  161 GLN B NE2 1 
ATOM   3122 N N   . ILE B 2 168 ? 75.036  118.072 138.207 1.00 58.13  ?  162 ILE B N   1 
ATOM   3123 C CA  . ILE B 2 168 ? 76.128  117.362 137.544 1.00 58.13  ?  162 ILE B CA  1 
ATOM   3124 C C   . ILE B 2 168 ? 77.212  117.064 138.569 1.00 58.13  ?  162 ILE B C   1 
ATOM   3125 O O   . ILE B 2 168 ? 77.627  117.950 139.321 1.00 58.13  ?  162 ILE B O   1 
ATOM   3126 C CB  . ILE B 2 168 ? 76.703  118.173 136.363 1.00 58.13  ?  162 ILE B CB  1 
ATOM   3127 C CG1 . ILE B 2 168 ? 77.772  117.359 135.629 1.00 58.13  ?  162 ILE B CG1 1 
ATOM   3128 C CG2 . ILE B 2 168 ? 77.282  119.495 136.852 1.00 58.13  ?  162 ILE B CG2 1 
ATOM   3129 C CD1 . ILE B 2 168 ? 78.354  118.062 134.423 1.00 58.13  ?  162 ILE B CD1 1 
ATOM   3130 N N   . VAL B 2 169 ? 77.675  115.819 138.597 1.00 58.89  ?  163 VAL B N   1 
ATOM   3131 C CA  . VAL B 2 169 ? 78.756  115.410 139.487 1.00 58.89  ?  163 VAL B CA  1 
ATOM   3132 C C   . VAL B 2 169 ? 80.076  115.547 138.744 1.00 58.89  ?  163 VAL B C   1 
ATOM   3133 O O   . VAL B 2 169 ? 80.157  115.284 137.538 1.00 58.89  ?  163 VAL B O   1 
ATOM   3134 C CB  . VAL B 2 169 ? 78.543  113.969 139.991 1.00 58.89  ?  163 VAL B CB  1 
ATOM   3135 C CG1 . VAL B 2 169 ? 78.641  112.968 138.843 1.00 58.89  ?  163 VAL B CG1 1 
ATOM   3136 C CG2 . VAL B 2 169 ? 79.546  113.633 141.086 1.00 58.89  ?  163 VAL B CG2 1 
ATOM   3137 N N   . THR B 2 170 ? 81.119  115.961 139.462 1.00 58.59  ?  164 THR B N   1 
ATOM   3138 C CA  . THR B 2 170 ? 82.433  116.155 138.872 1.00 58.59  ?  164 THR B CA  1 
ATOM   3139 C C   . THR B 2 170 ? 83.503  115.720 139.863 1.00 58.59  ?  164 THR B C   1 
ATOM   3140 O O   . THR B 2 170 ? 83.307  115.772 141.081 1.00 58.59  ?  164 THR B O   1 
ATOM   3141 C CB  . THR B 2 170 ? 82.668  117.619 138.470 1.00 58.59  ?  164 THR B CB  1 
ATOM   3142 O OG1 . THR B 2 170 ? 82.526  118.464 139.618 1.00 58.59  ?  164 THR B OG1 1 
ATOM   3143 C CG2 . THR B 2 170 ? 81.675  118.047 137.399 1.00 58.59  ?  164 THR B CG2 1 
ATOM   3144 N N   . SER B 2 171 ? 84.634  115.279 139.319 1.00 60.53  ?  165 SER B N   1 
ATOM   3145 C CA  . SER B 2 171 ? 85.793  114.872 140.100 1.00 60.53  ?  165 SER B CA  1 
ATOM   3146 C C   . SER B 2 171 ? 86.995  115.690 139.654 1.00 60.53  ?  165 SER B C   1 
ATOM   3147 O O   . SER B 2 171 ? 87.247  115.822 138.451 1.00 60.53  ?  165 SER B O   1 
ATOM   3148 C CB  . SER B 2 171 ? 86.076  113.378 139.932 1.00 60.53  ?  165 SER B CB  1 
ATOM   3149 O OG  . SER B 2 171 ? 86.215  113.035 138.564 1.00 60.53  ?  165 SER B OG  1 
ATOM   3150 N N   . SER B 2 172 ? 87.733  116.231 140.617 1.00 62.38  ?  166 SER B N   1 
ATOM   3151 C CA  . SER B 2 172 ? 88.873  117.092 140.345 1.00 62.38  ?  166 SER B CA  1 
ATOM   3152 C C   . SER B 2 172 ? 90.128  116.517 140.988 1.00 62.38  ?  166 SER B C   1 
ATOM   3153 O O   . SER B 2 172 ? 90.074  115.610 141.822 1.00 62.38  ?  166 SER B O   1 
ATOM   3154 C CB  . SER B 2 172 ? 88.618  118.514 140.859 1.00 62.38  ?  166 SER B CB  1 
ATOM   3155 O OG  . SER B 2 172 ? 89.701  119.370 140.540 1.00 62.38  ?  166 SER B OG  1 
ATOM   3156 N N   . GLY B 2 173 ? 91.274  117.065 140.582 1.00 63.65  ?  167 GLY B N   1 
ATOM   3157 C CA  . GLY B 2 173 ? 92.550  116.640 141.128 1.00 63.65  ?  167 GLY B CA  1 
ATOM   3158 C C   . GLY B 2 173 ? 92.779  117.034 142.571 1.00 63.65  ?  167 GLY B C   1 
ATOM   3159 O O   . GLY B 2 173 ? 93.792  116.628 143.151 1.00 63.65  ?  167 GLY B O   1 
ATOM   3160 N N   . ASP B 2 174 ? 91.872  117.809 143.162 1.00 63.60  ?  168 ASP B N   1 
ATOM   3161 C CA  . ASP B 2 174 ? 91.983  118.214 144.557 1.00 63.60  ?  168 ASP B CA  1 
ATOM   3162 C C   . ASP B 2 174 ? 91.581  117.110 145.529 1.00 63.60  ?  168 ASP B C   1 
ATOM   3163 O O   . ASP B 2 174 ? 91.507  117.366 146.736 1.00 63.60  ?  168 ASP B O   1 
ATOM   3164 C CB  . ASP B 2 174 ? 91.131  119.461 144.810 1.00 63.60  ?  168 ASP B CB  1 
ATOM   3165 C CG  . ASP B 2 174 ? 89.667  119.247 144.475 1.00 63.60  ?  168 ASP B CG  1 
ATOM   3166 O OD1 . ASP B 2 174 ? 89.303  118.119 144.082 1.00 63.60  ?  168 ASP B OD1 1 
ATOM   3167 O OD2 . ASP B 2 174 ? 88.880  120.209 144.605 1.00 63.60  ?  168 ASP B OD2 1 
ATOM   3168 N N   . THR B 2 175 ? 91.319  115.900 145.038 1.00 63.50  ?  169 THR B N   1 
ATOM   3169 C CA  . THR B 2 175 ? 90.968  114.715 145.813 1.00 63.50  ?  169 THR B CA  1 
ATOM   3170 C C   . THR B 2 175 ? 89.517  114.748 146.283 1.00 63.50  ?  169 THR B C   1 
ATOM   3171 O O   . THR B 2 175 ? 89.079  113.791 146.933 1.00 63.50  ?  169 THR B O   1 
ATOM   3172 C CB  . THR B 2 175 ? 91.871  114.519 147.042 1.00 63.50  ?  169 THR B CB  1 
ATOM   3173 O OG1 . THR B 2 175 ? 91.614  115.554 148.000 1.00 63.50  ?  169 THR B OG1 1 
ATOM   3174 C CG2 . THR B 2 175 ? 93.338  114.560 146.640 1.00 63.50  ?  169 THR B CG2 1 
ATOM   3175 N N   . THR B 2 176 ? 88.758  115.799 145.979 1.00 63.07  ?  170 THR B N   1 
ATOM   3176 C CA  . THR B 2 176 ? 87.380  115.937 146.430 1.00 63.07  ?  170 THR B CA  1 
ATOM   3177 C C   . THR B 2 176 ? 86.453  116.016 145.226 1.00 63.07  ?  170 THR B C   1 
ATOM   3178 O O   . THR B 2 176 ? 86.631  116.873 144.355 1.00 63.07  ?  170 THR B O   1 
ATOM   3179 C CB  . THR B 2 176 ? 87.204  117.186 147.300 1.00 63.07  ?  170 THR B CB  1 
ATOM   3180 O OG1 . THR B 2 176 ? 87.683  118.338 146.595 1.00 63.07  ?  170 THR B OG1 1 
ATOM   3181 C CG2 . THR B 2 176 ? 87.962  117.045 148.610 1.00 63.07  ?  170 THR B CG2 1 
ATOM   3182 N N   . CYS B 2 177 ? 85.469  115.124 145.183 1.00 61.90  ?  171 CYS B N   1 
ATOM   3183 C CA  . CYS B 2 177 ? 84.403  115.198 144.196 1.00 61.90  ?  171 CYS B CA  1 
ATOM   3184 C C   . CYS B 2 177 ? 83.315  116.145 144.689 1.00 61.90  ?  171 CYS B C   1 
ATOM   3185 O O   . CYS B 2 177 ? 83.221  116.455 145.879 1.00 61.90  ?  171 CYS B O   1 
ATOM   3186 C CB  . CYS B 2 177 ? 83.815  113.813 143.926 1.00 61.90  ?  171 CYS B CB  1 
ATOM   3187 S SG  . CYS B 2 177 ? 85.021  112.589 143.366 1.00 61.90  ?  171 CYS B SG  1 
ATOM   3188 N N   . ALA B 2 178 ? 82.486  116.608 143.757 1.00 59.54  ?  172 ALA B N   1 
ATOM   3189 C CA  . ALA B 2 178 ? 81.453  117.570 144.113 1.00 59.54  ?  172 ALA B CA  1 
ATOM   3190 C C   . ALA B 2 178 ? 80.300  117.486 143.125 1.00 59.54  ?  172 ALA B C   1 
ATOM   3191 O O   . ALA B 2 178 ? 80.515  117.372 141.916 1.00 59.54  ?  172 ALA B O   1 
ATOM   3192 C CB  . ALA B 2 178 ? 82.013  118.996 144.146 1.00 59.54  ?  172 ALA B CB  1 
ATOM   3193 N N   . LEU B 2 179 ? 79.082  117.547 143.654 1.00 59.76  ?  173 LEU B N   1 
ATOM   3194 C CA  . LEU B 2 179 ? 77.875  117.657 142.847 1.00 59.76  ?  173 LEU B CA  1 
ATOM   3195 C C   . LEU B 2 179 ? 77.474  119.126 142.797 1.00 59.76  ?  173 LEU B C   1 
ATOM   3196 O O   . LEU B 2 179 ? 77.189  119.729 143.839 1.00 59.76  ?  173 LEU B O   1 
ATOM   3197 C CB  . LEU B 2 179 ? 76.746  116.808 143.430 1.00 59.76  ?  173 LEU B CB  1 
ATOM   3198 C CG  . LEU B 2 179 ? 75.464  116.717 142.600 1.00 59.76  ?  173 LEU B CG  1 
ATOM   3199 C CD1 . LEU B 2 179 ? 75.663  115.813 141.395 1.00 59.76  ?  173 LEU B CD1 1 
ATOM   3200 C CD2 . LEU B 2 179 ? 74.311  116.224 143.457 1.00 59.76  ?  173 LEU B CD2 1 
ATOM   3201 N N   . TRP B 2 180 ? 77.473  119.696 141.595 1.00 58.33  ?  174 TRP B N   1 
ATOM   3202 C CA  . TRP B 2 180 ? 77.134  121.089 141.358 1.00 58.33  ?  174 TRP B CA  1 
ATOM   3203 C C   . TRP B 2 180 ? 75.738  121.200 140.757 1.00 58.33  ?  174 TRP B C   1 
ATOM   3204 O O   . TRP B 2 180 ? 75.221  120.262 140.142 1.00 58.33  ?  174 TRP B O   1 
ATOM   3205 C CB  . TRP B 2 180 ? 78.146  121.743 140.411 1.00 58.33  ?  174 TRP B CB  1 
ATOM   3206 C CG  . TRP B 2 180 ? 79.579  121.579 140.813 1.00 58.33  ?  174 TRP B CG  1 
ATOM   3207 C CD1 . TRP B 2 180 ? 80.317  120.432 140.773 1.00 58.33  ?  174 TRP B CD1 1 
ATOM   3208 C CD2 . TRP B 2 180 ? 80.456  122.603 141.297 1.00 58.33  ?  174 TRP B CD2 1 
ATOM   3209 N NE1 . TRP B 2 180 ? 81.596  120.676 141.210 1.00 58.33  ?  174 TRP B NE1 1 
ATOM   3210 C CE2 . TRP B 2 180 ? 81.707  122.001 141.537 1.00 58.33  ?  174 TRP B CE2 1 
ATOM   3211 C CE3 . TRP B 2 180 ? 80.304  123.969 141.554 1.00 58.33  ?  174 TRP B CE3 1 
ATOM   3212 C CZ2 . TRP B 2 180 ? 82.799  122.717 142.022 1.00 58.33  ?  174 TRP B CZ2 1 
ATOM   3213 C CZ3 . TRP B 2 180 ? 81.389  124.678 142.036 1.00 58.33  ?  174 TRP B CZ3 1 
ATOM   3214 C CH2 . TRP B 2 180 ? 82.620  124.051 142.266 1.00 58.33  ?  174 TRP B CH2 1 
ATOM   3215 N N   . ASP B 2 181 ? 75.139  122.375 140.933 1.00 60.02  ?  175 ASP B N   1 
ATOM   3216 C CA  . ASP B 2 181 ? 73.847  122.703 140.348 1.00 60.02  ?  175 ASP B CA  1 
ATOM   3217 C C   . ASP B 2 181 ? 74.062  123.613 139.146 1.00 60.02  ?  175 ASP B C   1 
ATOM   3218 O O   . ASP B 2 181 ? 74.797  124.602 139.234 1.00 60.02  ?  175 ASP B O   1 
ATOM   3219 C CB  . ASP B 2 181 ? 72.940  123.386 141.375 1.00 60.02  ?  175 ASP B CB  1 
ATOM   3220 C CG  . ASP B 2 181 ? 71.514  123.550 140.882 1.00 60.02  ?  175 ASP B CG  1 
ATOM   3221 O OD1 . ASP B 2 181 ? 71.317  123.774 139.670 1.00 60.02  ?  175 ASP B OD1 1 
ATOM   3222 O OD2 . ASP B 2 181 ? 70.585  123.453 141.712 1.00 60.02  ?  175 ASP B OD2 1 
ATOM   3223 N N   . ILE B 2 182 ? 73.421  123.276 138.027 1.00 59.61  ?  176 ILE B N   1 
ATOM   3224 C CA  . ILE B 2 182 ? 73.565  124.081 136.818 1.00 59.61  ?  176 ILE B CA  1 
ATOM   3225 C C   . ILE B 2 182 ? 72.928  125.451 137.016 1.00 59.61  ?  176 ILE B C   1 
ATOM   3226 O O   . ILE B 2 182 ? 73.546  126.487 136.741 1.00 59.61  ?  176 ILE B O   1 
ATOM   3227 C CB  . ILE B 2 182 ? 72.959  123.344 135.609 1.00 59.61  ?  176 ILE B CB  1 
ATOM   3228 C CG1 . ILE B 2 182 ? 73.620  121.972 135.439 1.00 59.61  ?  176 ILE B CG1 1 
ATOM   3229 C CG2 . ILE B 2 182 ? 73.124  124.172 134.337 1.00 59.61  ?  176 ILE B CG2 1 
ATOM   3230 C CD1 . ILE B 2 182 ? 73.047  121.147 134.304 1.00 59.61  ?  176 ILE B CD1 1 
ATOM   3231 N N   . GLU B 2 183 ? 71.684  125.478 137.497 1.00 62.95  ?  177 GLU B N   1 
ATOM   3232 C CA  . GLU B 2 183 ? 70.983  126.747 137.668 1.00 62.95  ?  177 GLU B CA  1 
ATOM   3233 C C   . GLU B 2 183 ? 71.716  127.652 138.650 1.00 62.95  ?  177 GLU B C   1 
ATOM   3234 O O   . GLU B 2 183 ? 71.933  128.839 138.377 1.00 62.95  ?  177 GLU B O   1 
ATOM   3235 C CB  . GLU B 2 183 ? 69.549  126.489 138.137 1.00 62.95  ?  177 GLU B CB  1 
ATOM   3236 C CG  . GLU B 2 183 ? 68.693  127.742 138.255 1.00 62.95  ?  177 GLU B CG  1 
ATOM   3237 C CD  . GLU B 2 183 ? 68.486  128.441 136.925 1.00 62.95  ?  177 GLU B CD  1 
ATOM   3238 O OE1 . GLU B 2 183 ? 68.817  127.844 135.878 1.00 62.95  ?  177 GLU B OE1 1 
ATOM   3239 O OE2 . GLU B 2 183 ? 67.993  129.589 136.925 1.00 62.95  ?  177 GLU B OE2 1 
ATOM   3240 N N   . THR B 2 184 ? 72.108  127.108 139.804 1.00 61.67  ?  178 THR B N   1 
ATOM   3241 C CA  . THR B 2 184 ? 72.789  127.915 140.810 1.00 61.67  ?  178 THR B CA  1 
ATOM   3242 C C   . THR B 2 184 ? 74.269  128.091 140.496 1.00 61.67  ?  178 THR B C   1 
ATOM   3243 O O   . THR B 2 184 ? 74.858  129.114 140.864 1.00 61.67  ?  178 THR B O   1 
ATOM   3244 C CB  . THR B 2 184 ? 72.626  127.281 142.193 1.00 61.67  ?  178 THR B CB  1 
ATOM   3245 O OG1 . THR B 2 184 ? 71.232  127.119 142.487 1.00 61.67  ?  178 THR B OG1 1 
ATOM   3246 C CG2 . THR B 2 184 ? 73.269  128.153 143.264 1.00 61.67  ?  178 THR B CG2 1 
ATOM   3247 N N   . GLY B 2 185 ? 74.882  127.121 139.824 1.00 61.23  ?  179 GLY B N   1 
ATOM   3248 C CA  . GLY B 2 185 ? 76.291  127.222 139.492 1.00 61.23  ?  179 GLY B CA  1 
ATOM   3249 C C   . GLY B 2 185 ? 77.218  127.088 140.678 1.00 61.23  ?  179 GLY B C   1 
ATOM   3250 O O   . GLY B 2 185 ? 78.314  127.656 140.665 1.00 61.23  ?  179 GLY B O   1 
ATOM   3251 N N   . GLN B 2 186 ? 76.808  126.349 141.707 1.00 60.50  ?  180 GLN B N   1 
ATOM   3252 C CA  . GLN B 2 186 ? 77.623  126.143 142.894 1.00 60.50  ?  180 GLN B CA  1 
ATOM   3253 C C   . GLN B 2 186 ? 77.512  124.687 143.325 1.00 60.50  ?  180 GLN B C   1 
ATOM   3254 O O   . GLN B 2 186 ? 76.686  123.925 142.815 1.00 60.50  ?  180 GLN B O   1 
ATOM   3255 C CB  . GLN B 2 186 ? 77.200  127.076 144.036 1.00 60.50  ?  180 GLN B CB  1 
ATOM   3256 C CG  . GLN B 2 186 ? 77.404  128.554 143.739 1.00 60.50  ?  180 GLN B CG  1 
ATOM   3257 C CD  . GLN B 2 186 ? 78.867  128.923 143.584 1.00 60.50  ?  180 GLN B CD  1 
ATOM   3258 O OE1 . GLN B 2 186 ? 79.755  128.112 143.844 1.00 60.50  ?  180 GLN B OE1 1 
ATOM   3259 N NE2 . GLN B 2 186 ? 79.124  130.154 143.159 1.00 60.50  ?  180 GLN B NE2 1 
ATOM   3260 N N   . GLN B 2 187 ? 78.359  124.306 144.278 1.00 59.05  ?  181 GLN B N   1 
ATOM   3261 C CA  . GLN B 2 187 ? 78.397  122.931 144.764 1.00 59.05  ?  181 GLN B CA  1 
ATOM   3262 C C   . GLN B 2 187 ? 77.110  122.616 145.516 1.00 59.05  ?  181 GLN B C   1 
ATOM   3263 O O   . GLN B 2 187 ? 76.897  123.106 146.629 1.00 59.05  ?  181 GLN B O   1 
ATOM   3264 C CB  . GLN B 2 187 ? 79.609  122.723 145.667 1.00 59.05  ?  181 GLN B CB  1 
ATOM   3265 C CG  . GLN B 2 187 ? 80.950  122.920 144.983 1.00 59.05  ?  181 GLN B CG  1 
ATOM   3266 C CD  . GLN B 2 187 ? 82.118  122.656 145.914 1.00 59.05  ?  181 GLN B CD  1 
ATOM   3267 O OE1 . GLN B 2 187 ? 81.931  122.394 147.102 1.00 59.05  ?  181 GLN B OE1 1 
ATOM   3268 N NE2 . GLN B 2 187 ? 83.331  122.723 145.378 1.00 59.05  ?  181 GLN B NE2 1 
ATOM   3269 N N   . THR B 2 188 ? 76.245  121.797 144.911 1.00 59.52  ?  182 THR B N   1 
ATOM   3270 C CA  . THR B 2 188 ? 75.102  121.274 145.652 1.00 59.52  ?  182 THR B CA  1 
ATOM   3271 C C   . THR B 2 188 ? 75.561  120.470 146.858 1.00 59.52  ?  182 THR B C   1 
ATOM   3272 O O   . THR B 2 188 ? 74.893  120.467 147.898 1.00 59.52  ?  182 THR B O   1 
ATOM   3273 C CB  . THR B 2 188 ? 74.230  120.408 144.742 1.00 59.52  ?  182 THR B CB  1 
ATOM   3274 O OG1 . THR B 2 188 ? 73.751  121.193 143.645 1.00 59.52  ?  182 THR B OG1 1 
ATOM   3275 C CG2 . THR B 2 188 ? 73.044  119.843 145.512 1.00 59.52  ?  182 THR B CG2 1 
ATOM   3276 N N   . THR B 2 189 ? 76.695  119.784 146.735 1.00 59.95  ?  183 THR B N   1 
ATOM   3277 C CA  . THR B 2 189 ? 77.274  119.058 147.857 1.00 59.95  ?  183 THR B CA  1 
ATOM   3278 C C   . THR B 2 189 ? 78.717  118.704 147.528 1.00 59.95  ?  183 THR B C   1 
ATOM   3279 O O   . THR B 2 189 ? 79.088  118.579 146.359 1.00 59.95  ?  183 THR B O   1 
ATOM   3280 C CB  . THR B 2 189 ? 76.475  117.791 148.191 1.00 59.95  ?  183 THR B CB  1 
ATOM   3281 O OG1 . THR B 2 189 ? 77.173  117.029 149.184 1.00 59.95  ?  183 THR B OG1 1 
ATOM   3282 C CG2 . THR B 2 189 ? 76.265  116.936 146.951 1.00 59.95  ?  183 THR B CG2 1 
ATOM   3283 N N   . THR B 2 190 ? 79.524  118.554 148.576 1.00 60.92  ?  184 THR B N   1 
ATOM   3284 C CA  . THR B 2 190 ? 80.937  118.229 148.445 1.00 60.92  ?  184 THR B CA  1 
ATOM   3285 C C   . THR B 2 190 ? 81.265  117.025 149.314 1.00 60.92  ?  184 THR B C   1 
ATOM   3286 O O   . THR B 2 190 ? 80.750  116.893 150.429 1.00 60.92  ?  184 THR B O   1 
ATOM   3287 C CB  . THR B 2 190 ? 81.827  119.417 148.843 1.00 60.92  ?  184 THR B CB  1 
ATOM   3288 O OG1 . THR B 2 190 ? 83.206  119.047 148.723 1.00 60.92  ?  184 THR B OG1 1 
ATOM   3289 C CG2 . THR B 2 190 ? 81.542  119.853 150.276 1.00 60.92  ?  184 THR B CG2 1 
ATOM   3290 N N   . PHE B 2 191 ? 82.122  116.150 148.798 1.00 64.19  ?  185 PHE B N   1 
ATOM   3291 C CA  . PHE B 2 191 ? 82.531  114.941 149.496 1.00 64.19  ?  185 PHE B CA  1 
ATOM   3292 C C   . PHE B 2 191 ? 83.925  115.118 150.085 1.00 64.19  ?  185 PHE B C   1 
ATOM   3293 O O   . PHE B 2 191 ? 84.738  115.900 149.585 1.00 64.19  ?  185 PHE B O   1 
ATOM   3294 C CB  . PHE B 2 191 ? 82.512  113.740 148.549 1.00 64.19  ?  185 PHE B CB  1 
ATOM   3295 C CG  . PHE B 2 191 ? 81.229  113.597 147.781 1.00 64.19  ?  185 PHE B CG  1 
ATOM   3296 C CD1 . PHE B 2 191 ? 81.094  114.158 146.522 1.00 64.19  ?  185 PHE B CD1 1 
ATOM   3297 C CD2 . PHE B 2 191 ? 80.155  112.908 148.320 1.00 64.19  ?  185 PHE B CD2 1 
ATOM   3298 C CE1 . PHE B 2 191 ? 79.915  114.031 145.814 1.00 64.19  ?  185 PHE B CE1 1 
ATOM   3299 C CE2 . PHE B 2 191 ? 78.973  112.779 147.615 1.00 64.19  ?  185 PHE B CE2 1 
ATOM   3300 C CZ  . PHE B 2 191 ? 78.853  113.341 146.361 1.00 64.19  ?  185 PHE B CZ  1 
ATOM   3301 N N   . THR B 2 192 ? 84.194  114.380 151.161 1.00 65.96  ?  186 THR B N   1 
ATOM   3302 C CA  . THR B 2 192 ? 85.493  114.463 151.814 1.00 65.96  ?  186 THR B CA  1 
ATOM   3303 C C   . THR B 2 192 ? 86.599  114.031 150.857 1.00 65.96  ?  186 THR B C   1 
ATOM   3304 O O   . THR B 2 192 ? 86.398  113.195 149.972 1.00 65.96  ?  186 THR B O   1 
ATOM   3305 C CB  . THR B 2 192 ? 85.519  113.591 153.071 1.00 65.96  ?  186 THR B CB  1 
ATOM   3306 O OG1 . THR B 2 192 ? 85.274  112.225 152.717 1.00 65.96  ?  186 THR B OG1 1 
ATOM   3307 C CG2 . THR B 2 192 ? 84.463  114.053 154.066 1.00 65.96  ?  186 THR B CG2 1 
ATOM   3308 N N   . GLY B 2 193 ? 87.780  114.614 151.044 1.00 65.92  ?  187 GLY B N   1 
ATOM   3309 C CA  . GLY B 2 193 ? 88.887  114.330 150.153 1.00 65.92  ?  187 GLY B CA  1 
ATOM   3310 C C   . GLY B 2 193 ? 89.408  112.915 150.315 1.00 65.92  ?  187 GLY B C   1 
ATOM   3311 O O   . GLY B 2 193 ? 89.350  112.318 151.390 1.00 65.92  ?  187 GLY B O   1 
ATOM   3312 N N   . HIS B 2 194 ? 89.929  112.375 149.217 1.00 65.67  ?  188 HIS B N   1 
ATOM   3313 C CA  . HIS B 2 194 ? 90.512  111.043 149.207 1.00 65.67  ?  188 HIS B CA  1 
ATOM   3314 C C   . HIS B 2 194 ? 91.990  111.137 149.583 1.00 65.67  ?  188 HIS B C   1 
ATOM   3315 O O   . HIS B 2 194 ? 92.492  112.199 149.962 1.00 65.67  ?  188 HIS B O   1 
ATOM   3316 C CB  . HIS B 2 194 ? 90.327  110.390 147.837 1.00 65.67  ?  188 HIS B CB  1 
ATOM   3317 C CG  . HIS B 2 194 ? 88.902  110.314 147.383 1.00 65.67  ?  188 HIS B CG  1 
ATOM   3318 N ND1 . HIS B 2 194 ? 88.535  109.730 146.191 1.00 65.67  ?  188 HIS B ND1 1 
ATOM   3319 C CD2 . HIS B 2 194 ? 87.755  110.749 147.958 1.00 65.67  ?  188 HIS B CD2 1 
ATOM   3320 C CE1 . HIS B 2 194 ? 87.224  109.807 146.050 1.00 65.67  ?  188 HIS B CE1 1 
ATOM   3321 N NE2 . HIS B 2 194 ? 86.727  110.422 147.108 1.00 65.67  ?  188 HIS B NE2 1 
ATOM   3322 N N   . THR B 2 195 ? 92.706  110.017 149.480 1.00 65.66  ?  189 THR B N   1 
ATOM   3323 C CA  . THR B 2 195 ? 94.148  110.024 149.688 1.00 65.66  ?  189 THR B CA  1 
ATOM   3324 C C   . THR B 2 195 ? 94.908  110.442 148.436 1.00 65.66  ?  189 THR B C   1 
ATOM   3325 O O   . THR B 2 195 ? 96.061  110.874 148.542 1.00 65.66  ?  189 THR B O   1 
ATOM   3326 C CB  . THR B 2 195 ? 94.623  108.641 150.142 1.00 65.66  ?  189 THR B CB  1 
ATOM   3327 O OG1 . THR B 2 195 ? 93.932  108.264 151.340 1.00 65.66  ?  189 THR B OG1 1 
ATOM   3328 C CG2 . THR B 2 195 ? 96.123  108.645 150.406 1.00 65.66  ?  189 THR B CG2 1 
ATOM   3329 N N   . GLY B 2 196 ? 94.288  110.326 147.260 1.00 64.30  ?  190 GLY B N   1 
ATOM   3330 C CA  . GLY B 2 196 ? 94.904  110.741 146.017 1.00 64.30  ?  190 GLY B CA  1 
ATOM   3331 C C   . GLY B 2 196 ? 93.900  111.449 145.128 1.00 64.30  ?  190 GLY B C   1 
ATOM   3332 O O   . GLY B 2 196 ? 92.743  111.650 145.505 1.00 64.30  ?  190 GLY B O   1 
ATOM   3333 N N   . ASP B 2 197 ? 94.364  111.821 143.939 1.00 64.82  ?  191 ASP B N   1 
ATOM   3334 C CA  . ASP B 2 197 ? 93.513  112.532 142.995 1.00 64.82  ?  191 ASP B CA  1 
ATOM   3335 C C   . ASP B 2 197 ? 92.514  111.579 142.351 1.00 64.82  ?  191 ASP B C   1 
ATOM   3336 O O   . ASP B 2 197 ? 92.866  110.474 141.929 1.00 64.82  ?  191 ASP B O   1 
ATOM   3337 C CB  . ASP B 2 197 ? 94.363  113.205 141.917 1.00 64.82  ?  191 ASP B CB  1 
ATOM   3338 C CG  . ASP B 2 197 ? 95.340  114.211 142.490 1.00 64.82  ?  191 ASP B CG  1 
ATOM   3339 O OD1 . ASP B 2 197 ? 95.357  114.389 143.726 1.00 64.82  ?  191 ASP B OD1 1 
ATOM   3340 O OD2 . ASP B 2 197 ? 96.093  114.825 141.704 1.00 64.82  ?  191 ASP B OD2 1 
ATOM   3341 N N   . VAL B 2 198 ? 91.261  112.016 142.275 1.00 62.83  ?  192 VAL B N   1 
ATOM   3342 C CA  . VAL B 2 198 ? 90.210  111.216 141.655 1.00 62.83  ?  192 VAL B CA  1 
ATOM   3343 C C   . VAL B 2 198 ? 90.370  111.292 140.143 1.00 62.83  ?  192 VAL B C   1 
ATOM   3344 O O   . VAL B 2 198 ? 90.520  112.381 139.576 1.00 62.83  ?  192 VAL B O   1 
ATOM   3345 C CB  . VAL B 2 198 ? 88.821  111.703 142.098 1.00 62.83  ?  192 VAL B CB  1 
ATOM   3346 C CG1 . VAL B 2 198 ? 87.743  110.711 141.665 1.00 62.83  ?  192 VAL B CG1 1 
ATOM   3347 C CG2 . VAL B 2 198 ? 88.787  111.919 143.606 1.00 62.83  ?  192 VAL B CG2 1 
ATOM   3348 N N   . MET B 2 199 ? 90.336  110.130 139.484 1.00 63.95  ?  193 MET B N   1 
ATOM   3349 C CA  . MET B 2 199 ? 90.627  110.041 138.061 1.00 63.95  ?  193 MET B CA  1 
ATOM   3350 C C   . MET B 2 199 ? 89.440  109.625 137.206 1.00 63.95  ?  193 MET B C   1 
ATOM   3351 O O   . MET B 2 199 ? 89.473  109.848 135.992 1.00 63.95  ?  193 MET B O   1 
ATOM   3352 C CB  . MET B 2 199 ? 91.773  109.046 137.819 1.00 63.95  ?  193 MET B CB  1 
ATOM   3353 C CG  . MET B 2 199 ? 93.078  109.421 138.505 1.00 63.95  ?  193 MET B CG  1 
ATOM   3354 S SD  . MET B 2 199 ? 93.767  110.983 137.922 1.00 63.95  ?  193 MET B SD  1 
ATOM   3355 C CE  . MET B 2 199 ? 94.098  110.595 136.205 1.00 63.95  ?  193 MET B CE  1 
ATOM   3356 N N   . SER B 2 200 ? 88.403  109.029 137.791 1.00 63.03  ?  194 SER B N   1 
ATOM   3357 C CA  . SER B 2 200 ? 87.274  108.550 137.008 1.00 63.03  ?  194 SER B CA  1 
ATOM   3358 C C   . SER B 2 200 ? 86.014  108.564 137.861 1.00 63.03  ?  194 SER B C   1 
ATOM   3359 O O   . SER B 2 200 ? 86.069  108.674 139.089 1.00 63.03  ?  194 SER B O   1 
ATOM   3360 C CB  . SER B 2 200 ? 87.532  107.139 136.464 1.00 63.03  ?  194 SER B CB  1 
ATOM   3361 O OG  . SER B 2 200 ? 87.799  106.228 137.516 1.00 63.03  ?  194 SER B OG  1 
ATOM   3362 N N   . LEU B 2 201 ? 84.872  108.448 137.185 1.00 61.16  ?  195 LEU B N   1 
ATOM   3363 C CA  . LEU B 2 201 ? 83.573  108.422 137.841 1.00 61.16  ?  195 LEU B CA  1 
ATOM   3364 C C   . LEU B 2 201 ? 82.668  107.454 137.094 1.00 61.16  ?  195 LEU B C   1 
ATOM   3365 O O   . LEU B 2 201 ? 82.943  107.069 135.955 1.00 61.16  ?  195 LEU B O   1 
ATOM   3366 C CB  . LEU B 2 201 ? 82.931  109.815 137.886 1.00 61.16  ?  195 LEU B CB  1 
ATOM   3367 C CG  . LEU B 2 201 ? 83.635  110.887 138.720 1.00 61.16  ?  195 LEU B CG  1 
ATOM   3368 C CD1 . LEU B 2 201 ? 82.952  112.232 138.532 1.00 61.16  ?  195 LEU B CD1 1 
ATOM   3369 C CD2 . LEU B 2 201 ? 83.657  110.500 140.189 1.00 61.16  ?  195 LEU B CD2 1 
ATOM   3370 N N   . SER B 2 202 ? 81.579  107.062 137.753 1.00 62.68  ?  196 SER B N   1 
ATOM   3371 C CA  . SER B 2 202 ? 80.607  106.155 137.147 1.00 62.68  ?  196 SER B CA  1 
ATOM   3372 C C   . SER B 2 202 ? 79.307  106.251 137.926 1.00 62.68  ?  196 SER B C   1 
ATOM   3373 O O   . SER B 2 202 ? 79.297  106.023 139.140 1.00 62.68  ?  196 SER B O   1 
ATOM   3374 C CB  . SER B 2 202 ? 81.130  104.718 137.140 1.00 62.68  ?  196 SER B CB  1 
ATOM   3375 O OG  . SER B 2 202 ? 81.433  104.280 138.453 1.00 62.68  ?  196 SER B OG  1 
ATOM   3376 N N   . LEU B 2 203 ? 78.219  106.582 137.237 1.00 61.13  ?  197 LEU B N   1 
ATOM   3377 C CA  . LEU B 2 203 ? 76.913  106.703 137.865 1.00 61.13  ?  197 LEU B CA  1 
ATOM   3378 C C   . LEU B 2 203 ? 76.183  105.366 137.850 1.00 61.13  ?  197 LEU B C   1 
ATOM   3379 O O   . LEU B 2 203 ? 76.329  104.563 136.924 1.00 61.13  ?  197 LEU B O   1 
ATOM   3380 C CB  . LEU B 2 203 ? 76.063  107.759 137.155 1.00 61.13  ?  197 LEU B CB  1 
ATOM   3381 C CG  . LEU B 2 203 ? 76.544  109.208 137.241 1.00 61.13  ?  197 LEU B CG  1 
ATOM   3382 C CD1 . LEU B 2 203 ? 75.604  110.120 136.469 1.00 61.13  ?  197 LEU B CD1 1 
ATOM   3383 C CD2 . LEU B 2 203 ? 76.658  109.659 138.689 1.00 61.13  ?  197 LEU B CD2 1 
ATOM   3384 N N   . ALA B 2 204 ? 75.390  105.137 138.891 1.00 66.60  ?  198 ALA B N   1 
ATOM   3385 C CA  . ALA B 2 204 ? 74.575  103.940 138.984 1.00 66.60  ?  198 ALA B CA  1 
ATOM   3386 C C   . ALA B 2 204 ? 73.268  104.128 138.219 1.00 66.60  ?  198 ALA B C   1 
ATOM   3387 O O   . ALA B 2 204 ? 72.836  105.258 137.978 1.00 66.60  ?  198 ALA B O   1 
ATOM   3388 C CB  . ALA B 2 204 ? 74.290  103.615 140.446 1.00 66.60  ?  198 ALA B CB  1 
ATOM   3389 N N   . PRO B 2 205 ? 72.616  103.032 137.821 1.00 67.26  ?  199 PRO B N   1 
ATOM   3390 C CA  . PRO B 2 205 ? 71.346  103.177 137.090 1.00 67.26  ?  199 PRO B CA  1 
ATOM   3391 C C   . PRO B 2 205 ? 70.279  103.915 137.877 1.00 67.26  ?  199 PRO B C   1 
ATOM   3392 O O   . PRO B 2 205 ? 69.402  104.545 137.273 1.00 67.26  ?  199 PRO B O   1 
ATOM   3393 C CB  . PRO B 2 205 ? 70.938  101.724 136.800 1.00 67.26  ?  199 PRO B CB  1 
ATOM   3394 C CG  . PRO B 2 205 ? 71.699  100.899 137.784 1.00 67.26  ?  199 PRO B CG  1 
ATOM   3395 C CD  . PRO B 2 205 ? 72.990  101.619 138.000 1.00 67.26  ?  199 PRO B CD  1 
ATOM   3396 N N   . ASP B 2 206 ? 70.324  103.859 139.209 1.00 67.74  ?  200 ASP B N   1 
ATOM   3397 C CA  . ASP B 2 206 ? 69.358  104.584 140.026 1.00 67.74  ?  200 ASP B CA  1 
ATOM   3398 C C   . ASP B 2 206 ? 69.728  106.050 140.206 1.00 67.74  ?  200 ASP B C   1 
ATOM   3399 O O   . ASP B 2 206 ? 68.872  106.844 140.610 1.00 67.74  ?  200 ASP B O   1 
ATOM   3400 C CB  . ASP B 2 206 ? 69.222  103.917 141.397 1.00 67.74  ?  200 ASP B CB  1 
ATOM   3401 C CG  . ASP B 2 206 ? 70.533  103.871 142.158 1.00 67.74  ?  200 ASP B CG  1 
ATOM   3402 O OD1 . ASP B 2 206 ? 71.562  104.307 141.602 1.00 67.74  ?  200 ASP B OD1 1 
ATOM   3403 O OD2 . ASP B 2 206 ? 70.533  103.398 143.314 1.00 67.74  ?  200 ASP B OD2 1 
ATOM   3404 N N   . THR B 2 207 ? 70.976  106.423 139.923 1.00 65.74  ?  201 THR B N   1 
ATOM   3405 C CA  . THR B 2 207 ? 71.479  107.789 140.034 1.00 65.74  ?  201 THR B CA  1 
ATOM   3406 C C   . THR B 2 207 ? 71.596  108.254 141.480 1.00 65.74  ?  201 THR B C   1 
ATOM   3407 O O   . THR B 2 207 ? 71.940  109.417 141.725 1.00 65.74  ?  201 THR B O   1 
ATOM   3408 C CB  . THR B 2 207 ? 70.599  108.776 139.253 1.00 65.74  ?  201 THR B CB  1 
ATOM   3409 O OG1 . THR B 2 207 ? 70.281  108.224 137.969 1.00 65.74  ?  201 THR B OG1 1 
ATOM   3410 C CG2 . THR B 2 207 ? 71.316  110.107 139.055 1.00 65.74  ?  201 THR B CG2 1 
ATOM   3411 N N   . ARG B 2 208 ? 71.333  107.378 142.451 1.00 69.81  ?  202 ARG B N   1 
ATOM   3412 C CA  . ARG B 2 208 ? 71.414  107.750 143.858 1.00 69.81  ?  202 ARG B CA  1 
ATOM   3413 C C   . ARG B 2 208 ? 72.818  107.569 144.421 1.00 69.81  ?  202 ARG B C   1 
ATOM   3414 O O   . ARG B 2 208 ? 73.247  108.354 145.274 1.00 69.81  ?  202 ARG B O   1 
ATOM   3415 C CB  . ARG B 2 208 ? 70.417  106.925 144.677 1.00 69.81  ?  202 ARG B CB  1 
ATOM   3416 C CG  . ARG B 2 208 ? 68.984  106.983 144.161 1.00 69.81  ?  202 ARG B CG  1 
ATOM   3417 C CD  . ARG B 2 208 ? 68.442  108.405 144.149 1.00 69.81  ?  202 ARG B CD  1 
ATOM   3418 N NE  . ARG B 2 208 ? 67.056  108.460 143.695 1.00 69.81  ?  202 ARG B NE  1 
ATOM   3419 C CZ  . ARG B 2 208 ? 66.354  109.581 143.559 1.00 69.81  ?  202 ARG B CZ  1 
ATOM   3420 N NH1 . ARG B 2 208 ? 66.904  110.755 143.842 1.00 69.81  1  202 ARG B NH1 1 
ATOM   3421 N NH2 . ARG B 2 208 ? 65.097  109.529 143.139 1.00 69.81  ?  202 ARG B NH2 1 
ATOM   3422 N N   . LEU B 2 209 ? 73.542  106.550 143.964 1.00 67.97  ?  203 LEU B N   1 
ATOM   3423 C CA  . LEU B 2 209 ? 74.899  106.278 144.410 1.00 67.97  ?  203 LEU B CA  1 
ATOM   3424 C C   . LEU B 2 209 ? 75.837  106.248 143.211 1.00 67.97  ?  203 LEU B C   1 
ATOM   3425 O O   . LEU B 2 209 ? 75.424  105.982 142.079 1.00 67.97  ?  203 LEU B O   1 
ATOM   3426 C CB  . LEU B 2 209 ? 74.978  104.943 145.165 1.00 67.97  ?  203 LEU B CB  1 
ATOM   3427 C CG  . LEU B 2 209 ? 74.001  104.766 146.330 1.00 67.97  ?  203 LEU B CG  1 
ATOM   3428 C CD1 . LEU B 2 209 ? 74.165  103.390 146.957 1.00 67.97  ?  203 LEU B CD1 1 
ATOM   3429 C CD2 . LEU B 2 209 ? 74.193  105.857 147.370 1.00 67.97  ?  203 LEU B CD2 1 
ATOM   3430 N N   . PHE B 2 210 ? 77.113  106.527 143.470 1.00 65.15  ?  204 PHE B N   1 
ATOM   3431 C CA  . PHE B 2 210 ? 78.124  106.482 142.424 1.00 65.15  ?  204 PHE B CA  1 
ATOM   3432 C C   . PHE B 2 210 ? 79.475  106.167 143.049 1.00 65.15  ?  204 PHE B C   1 
ATOM   3433 O O   . PHE B 2 210 ? 79.821  106.709 144.100 1.00 65.15  ?  204 PHE B O   1 
ATOM   3434 C CB  . PHE B 2 210 ? 78.190  107.803 141.646 1.00 65.15  ?  204 PHE B CB  1 
ATOM   3435 C CG  . PHE B 2 210 ? 78.725  108.956 142.446 1.00 65.15  ?  204 PHE B CG  1 
ATOM   3436 C CD1 . PHE B 2 210 ? 77.888  109.700 143.261 1.00 65.15  ?  204 PHE B CD1 1 
ATOM   3437 C CD2 . PHE B 2 210 ? 80.064  109.303 142.374 1.00 65.15  ?  204 PHE B CD2 1 
ATOM   3438 C CE1 . PHE B 2 210 ? 78.379  110.764 143.995 1.00 65.15  ?  204 PHE B CE1 1 
ATOM   3439 C CE2 . PHE B 2 210 ? 80.560  110.365 143.105 1.00 65.15  ?  204 PHE B CE2 1 
ATOM   3440 C CZ  . PHE B 2 210 ? 79.716  111.097 143.915 1.00 65.15  ?  204 PHE B CZ  1 
ATOM   3441 N N   . VAL B 2 211 ? 80.229  105.287 142.397 1.00 65.10  ?  205 VAL B N   1 
ATOM   3442 C CA  . VAL B 2 211 ? 81.531  104.847 142.885 1.00 65.10  ?  205 VAL B CA  1 
ATOM   3443 C C   . VAL B 2 211 ? 82.618  105.591 142.124 1.00 65.10  ?  205 VAL B C   1 
ATOM   3444 O O   . VAL B 2 211 ? 82.501  105.821 140.913 1.00 65.10  ?  205 VAL B O   1 
ATOM   3445 C CB  . VAL B 2 211 ? 81.692  103.322 142.737 1.00 65.10  ?  205 VAL B CB  1 
ATOM   3446 C CG1 . VAL B 2 211 ? 81.740  102.925 141.266 1.00 65.10  ?  205 VAL B CG1 1 
ATOM   3447 C CG2 . VAL B 2 211 ? 82.932  102.841 143.477 1.00 65.10  ?  205 VAL B CG2 1 
ATOM   3448 N N   . SER B 2 212 ? 83.680  105.970 142.834 1.00 64.39  ?  206 SER B N   1 
ATOM   3449 C CA  . SER B 2 212 ? 84.774  106.733 142.252 1.00 64.39  ?  206 SER B CA  1 
ATOM   3450 C C   . SER B 2 212 ? 86.098  106.256 142.828 1.00 64.39  ?  206 SER B C   1 
ATOM   3451 O O   . SER B 2 212 ? 86.202  105.988 144.029 1.00 64.39  ?  206 SER B O   1 
ATOM   3452 C CB  . SER B 2 212 ? 84.605  108.235 142.514 1.00 64.39  ?  206 SER B CB  1 
ATOM   3453 O OG  . SER B 2 212 ? 84.592  108.512 143.903 1.00 64.39  ?  206 SER B OG  1 
ATOM   3454 N N   . GLY B 2 213 ? 87.106  106.160 141.965 1.00 63.51  ?  207 GLY B N   1 
ATOM   3455 C CA  . GLY B 2 213 ? 88.440  105.767 142.374 1.00 63.51  ?  207 GLY B CA  1 
ATOM   3456 C C   . GLY B 2 213 ? 89.428  106.896 142.152 1.00 63.51  ?  207 GLY B C   1 
ATOM   3457 O O   . GLY B 2 213 ? 89.215  107.772 141.312 1.00 63.51  ?  207 GLY B O   1 
ATOM   3458 N N   . ALA B 2 214 ? 90.516  106.868 142.918 1.00 63.84  ?  208 ALA B N   1 
ATOM   3459 C CA  . ALA B 2 214 ? 91.552  107.890 142.860 1.00 63.84  ?  208 ALA B CA  1 
ATOM   3460 C C   . ALA B 2 214 ? 92.918  107.218 142.762 1.00 63.84  ?  208 ALA B C   1 
ATOM   3461 O O   . ALA B 2 214 ? 93.027  105.992 142.663 1.00 63.84  ?  208 ALA B O   1 
ATOM   3462 C CB  . ALA B 2 214 ? 91.479  108.817 144.080 1.00 63.84  ?  208 ALA B CB  1 
ATOM   3463 N N   . CYS B 2 215 ? 93.970  108.040 142.785 1.00 64.86  ?  209 CYS B N   1 
ATOM   3464 C CA  . CYS B 2 215 ? 95.327  107.511 142.679 1.00 64.86  ?  209 CYS B CA  1 
ATOM   3465 C C   . CYS B 2 215 ? 95.595  106.460 143.748 1.00 64.86  ?  209 CYS B C   1 
ATOM   3466 O O   . CYS B 2 215 ? 96.287  105.467 143.493 1.00 64.86  ?  209 CYS B O   1 
ATOM   3467 C CB  . CYS B 2 215 ? 96.343  108.648 142.782 1.00 64.86  ?  209 CYS B CB  1 
ATOM   3468 S SG  . CYS B 2 215 ? 96.310  109.804 141.394 1.00 64.86  ?  209 CYS B SG  1 
ATOM   3469 N N   . ASP B 2 216 ? 95.065  106.660 144.951 1.00 65.24  ?  210 ASP B N   1 
ATOM   3470 C CA  . ASP B 2 216 ? 95.230  105.668 146.002 1.00 65.24  ?  210 ASP B CA  1 
ATOM   3471 C C   . ASP B 2 216 ? 94.515  104.376 145.622 1.00 65.24  ?  210 ASP B C   1 
ATOM   3472 O O   . ASP B 2 216 ? 93.484  104.385 144.943 1.00 65.24  ?  210 ASP B O   1 
ATOM   3473 C CB  . ASP B 2 216 ? 94.689  106.201 147.329 1.00 65.24  ?  210 ASP B CB  1 
ATOM   3474 C CG  . ASP B 2 216 ? 93.197  106.458 147.289 1.00 65.24  ?  210 ASP B CG  1 
ATOM   3475 O OD1 . ASP B 2 216 ? 92.655  106.646 146.181 1.00 65.24  ?  210 ASP B OD1 1 
ATOM   3476 O OD2 . ASP B 2 216 ? 92.565  106.471 148.367 1.00 65.24  ?  210 ASP B OD2 1 
ATOM   3477 N N   . ALA B 2 217 ? 95.076  103.253 146.068 1.00 67.28  ?  211 ALA B N   1 
ATOM   3478 C CA  . ALA B 2 217 ? 94.537  101.932 145.745 1.00 67.28  ?  211 ALA B CA  1 
ATOM   3479 C C   . ALA B 2 217 ? 93.270  101.706 146.564 1.00 67.28  ?  211 ALA B C   1 
ATOM   3480 O O   . ALA B 2 217 ? 93.243  100.956 147.544 1.00 67.28  ?  211 ALA B O   1 
ATOM   3481 C CB  . ALA B 2 217 ? 95.576  100.850 146.011 1.00 67.28  ?  211 ALA B CB  1 
ATOM   3482 N N   . SER B 2 218 ? 92.196  102.372 146.149 1.00 67.36  ?  212 SER B N   1 
ATOM   3483 C CA  . SER B 2 218 ? 90.913  102.255 146.828 1.00 67.36  ?  212 SER B CA  1 
ATOM   3484 C C   . SER B 2 218 ? 89.853  102.965 146.000 1.00 67.36  ?  212 SER B C   1 
ATOM   3485 O O   . SER B 2 218 ? 90.162  103.824 145.169 1.00 67.36  ?  212 SER B O   1 
ATOM   3486 C CB  . SER B 2 218 ? 90.971  102.840 148.244 1.00 67.36  ?  212 SER B CB  1 
ATOM   3487 O OG  . SER B 2 218 ? 91.449  104.174 148.224 1.00 67.36  ?  212 SER B OG  1 
ATOM   3488 N N   . ALA B 2 219 ? 88.597  102.592 146.240 1.00 67.57  ?  213 ALA B N   1 
ATOM   3489 C CA  . ALA B 2 219 ? 87.457  103.186 145.555 1.00 67.57  ?  213 ALA B CA  1 
ATOM   3490 C C   . ALA B 2 219 ? 86.328  103.391 146.553 1.00 67.57  ?  213 ALA B C   1 
ATOM   3491 O O   . ALA B 2 219 ? 86.006  102.488 147.330 1.00 67.57  ?  213 ALA B O   1 
ATOM   3492 C CB  . ALA B 2 219 ? 86.979  102.307 144.393 1.00 67.57  ?  213 ALA B CB  1 
ATOM   3493 N N   . LYS B 2 220 ? 85.722  104.574 146.521 1.00 69.15  ?  214 LYS B N   1 
ATOM   3494 C CA  . LYS B 2 220 ? 84.694  104.959 147.477 1.00 69.15  ?  214 LYS B CA  1 
ATOM   3495 C C   . LYS B 2 220 ? 83.346  105.090 146.780 1.00 69.15  ?  214 LYS B C   1 
ATOM   3496 O O   . LYS B 2 220 ? 83.256  105.650 145.683 1.00 69.15  ?  214 LYS B O   1 
ATOM   3497 C CB  . LYS B 2 220 ? 85.057  106.278 148.164 1.00 69.15  ?  214 LYS B CB  1 
ATOM   3498 C CG  . LYS B 2 220 ? 86.399  106.250 148.880 1.00 69.15  ?  214 LYS B CG  1 
ATOM   3499 C CD  . LYS B 2 220 ? 86.723  107.594 149.510 1.00 69.15  ?  214 LYS B CD  1 
ATOM   3500 C CE  . LYS B 2 220 ? 88.099  107.592 150.156 1.00 69.15  ?  214 LYS B CE  1 
ATOM   3501 N NZ  . LYS B 2 220 ? 88.214  106.571 151.234 1.00 69.15  1  214 LYS B NZ  1 
ATOM   3502 N N   . LEU B 2 221 ? 82.301  104.575 147.427 1.00 69.73  ?  215 LEU B N   1 
ATOM   3503 C CA  . LEU B 2 221 ? 80.936  104.624 146.903 1.00 69.73  ?  215 LEU B CA  1 
ATOM   3504 C C   . LEU B 2 221 ? 80.196  105.751 147.614 1.00 69.73  ?  215 LEU B C   1 
ATOM   3505 O O   . LEU B 2 221 ? 79.702  105.576 148.731 1.00 69.73  ?  215 LEU B O   1 
ATOM   3506 C CB  . LEU B 2 221 ? 80.233  103.285 147.102 1.00 69.73  ?  215 LEU B CB  1 
ATOM   3507 C CG  . LEU B 2 221 ? 78.796  103.194 146.583 1.00 69.73  ?  215 LEU B CG  1 
ATOM   3508 C CD1 . LEU B 2 221 ? 78.768  103.194 145.063 1.00 69.73  ?  215 LEU B CD1 1 
ATOM   3509 C CD2 . LEU B 2 221 ? 78.104  101.959 147.138 1.00 69.73  ?  215 LEU B CD2 1 
ATOM   3510 N N   . TRP B 2 222 ? 80.113  106.906 146.962 1.00 68.22  ?  216 TRP B N   1 
ATOM   3511 C CA  . TRP B 2 222 ? 79.455  108.069 147.533 1.00 68.22  ?  216 TRP B CA  1 
ATOM   3512 C C   . TRP B 2 222 ? 77.972  108.080 147.173 1.00 68.22  ?  216 TRP B C   1 
ATOM   3513 O O   . TRP B 2 222 ? 77.528  107.434 146.220 1.00 68.22  ?  216 TRP B O   1 
ATOM   3514 C CB  . TRP B 2 222 ? 80.120  109.355 147.042 1.00 68.22  ?  216 TRP B CB  1 
ATOM   3515 C CG  . TRP B 2 222 ? 81.586  109.410 147.327 1.00 68.22  ?  216 TRP B CG  1 
ATOM   3516 C CD1 . TRP B 2 222 ? 82.600  109.071 146.480 1.00 68.22  ?  216 TRP B CD1 1 
ATOM   3517 C CD2 . TRP B 2 222 ? 82.207  109.827 148.549 1.00 68.22  ?  216 TRP B CD2 1 
ATOM   3518 N NE1 . TRP B 2 222 ? 83.814  109.253 147.097 1.00 68.22  ?  216 TRP B NE1 1 
ATOM   3519 C CE2 . TRP B 2 222 ? 83.599  109.715 148.369 1.00 68.22  ?  216 TRP B CE2 1 
ATOM   3520 C CE3 . TRP B 2 222 ? 81.720  110.284 149.777 1.00 68.22  ?  216 TRP B CE3 1 
ATOM   3521 C CZ2 . TRP B 2 222 ? 84.510  110.044 149.370 1.00 68.22  ?  216 TRP B CZ2 1 
ATOM   3522 C CZ3 . TRP B 2 222 ? 82.626  110.609 150.770 1.00 68.22  ?  216 TRP B CZ3 1 
ATOM   3523 C CH2 . TRP B 2 222 ? 84.004  110.488 150.560 1.00 68.22  ?  216 TRP B CH2 1 
ATOM   3524 N N   . ASP B 2 223 ? 77.206  108.832 147.960 1.00 69.35  ?  217 ASP B N   1 
ATOM   3525 C CA  . ASP B 2 223 ? 75.768  108.965 147.786 1.00 69.35  ?  217 ASP B CA  1 
ATOM   3526 C C   . ASP B 2 223 ? 75.432  110.391 147.371 1.00 69.35  ?  217 ASP B C   1 
ATOM   3527 O O   . ASP B 2 223 ? 76.061  111.348 147.833 1.00 69.35  ?  217 ASP B O   1 
ATOM   3528 C CB  . ASP B 2 223 ? 75.026  108.606 149.077 1.00 69.35  ?  217 ASP B CB  1 
ATOM   3529 C CG  . ASP B 2 223 ? 73.518  108.679 148.928 1.00 69.35  ?  217 ASP B CG  1 
ATOM   3530 O OD1 . ASP B 2 223 ? 73.036  108.925 147.803 1.00 69.35  ?  217 ASP B OD1 1 
ATOM   3531 O OD2 . ASP B 2 223 ? 72.811  108.489 149.941 1.00 69.35  ?  217 ASP B OD2 1 
ATOM   3532 N N   . VAL B 2 224 ? 74.436  110.527 146.495 1.00 65.80  ?  218 VAL B N   1 
ATOM   3533 C CA  . VAL B 2 224 ? 74.028  111.851 146.040 1.00 65.80  ?  218 VAL B CA  1 
ATOM   3534 C C   . VAL B 2 224 ? 73.222  112.574 147.113 1.00 65.80  ?  218 VAL B C   1 
ATOM   3535 O O   . VAL B 2 224 ? 73.250  113.808 147.188 1.00 65.80  ?  218 VAL B O   1 
ATOM   3536 C CB  . VAL B 2 224 ? 73.233  111.736 144.727 1.00 65.80  ?  218 VAL B CB  1 
ATOM   3537 C CG1 . VAL B 2 224 ? 72.771  113.112 144.258 1.00 65.80  ?  218 VAL B CG1 1 
ATOM   3538 C CG2 . VAL B 2 224 ? 74.075  111.049 143.659 1.00 65.80  ?  218 VAL B CG2 1 
ATOM   3539 N N   . ARG B 2 225 ? 72.499  111.835 147.956 1.00 70.60  ?  219 ARG B N   1 
ATOM   3540 C CA  . ARG B 2 225 ? 71.682  112.473 148.984 1.00 70.60  ?  219 ARG B CA  1 
ATOM   3541 C C   . ARG B 2 225 ? 72.549  113.032 150.107 1.00 70.60  ?  219 ARG B C   1 
ATOM   3542 O O   . ARG B 2 225 ? 72.368  114.179 150.531 1.00 70.60  ?  219 ARG B O   1 
ATOM   3543 C CB  . ARG B 2 225 ? 70.663  111.474 149.533 1.00 70.60  ?  219 ARG B CB  1 
ATOM   3544 C CG  . ARG B 2 225 ? 69.626  111.032 148.513 1.00 70.60  ?  219 ARG B CG  1 
ATOM   3545 C CD  . ARG B 2 225 ? 68.641  110.041 149.113 1.00 70.60  ?  219 ARG B CD  1 
ATOM   3546 N NE  . ARG B 2 225 ? 67.631  109.621 148.146 1.00 70.60  ?  219 ARG B NE  1 
ATOM   3547 C CZ  . ARG B 2 225 ? 66.654  108.758 148.409 1.00 70.60  ?  219 ARG B CZ  1 
ATOM   3548 N NH1 . ARG B 2 225 ? 66.547  108.214 149.614 1.00 70.60  1  219 ARG B NH1 1 
ATOM   3549 N NH2 . ARG B 2 225 ? 65.781  108.438 147.463 1.00 70.60  ?  219 ARG B NH2 1 
ATOM   3550 N N   . GLU B 2 226 ? 73.496  112.236 150.600 1.00 71.81  ?  220 GLU B N   1 
ATOM   3551 C CA  . GLU B 2 226 ? 74.400  112.653 151.663 1.00 71.81  ?  220 GLU B CA  1 
ATOM   3552 C C   . GLU B 2 226 ? 75.839  112.476 151.202 1.00 71.81  ?  220 GLU B C   1 
ATOM   3553 O O   . GLU B 2 226 ? 76.159  111.521 150.489 1.00 71.81  ?  220 GLU B O   1 
ATOM   3554 C CB  . GLU B 2 226 ? 74.167  111.851 152.952 1.00 71.81  ?  220 GLU B CB  1 
ATOM   3555 C CG  . GLU B 2 226 ? 72.805  112.077 153.595 1.00 71.81  ?  220 GLU B CG  1 
ATOM   3556 C CD  . GLU B 2 226 ? 71.680  111.380 152.854 1.00 71.81  ?  220 GLU B CD  1 
ATOM   3557 O OE1 . GLU B 2 226 ? 71.967  110.448 152.075 1.00 71.81  ?  220 GLU B OE1 1 
ATOM   3558 O OE2 . GLU B 2 226 ? 70.508  111.766 153.051 1.00 71.81  ?  220 GLU B OE2 1 
ATOM   3559 N N   . GLY B 2 227 ? 76.701  113.402 151.615 1.00 69.60  ?  221 GLY B N   1 
ATOM   3560 C CA  . GLY B 2 227 ? 78.102  113.345 151.249 1.00 69.60  ?  221 GLY B CA  1 
ATOM   3561 C C   . GLY B 2 227 ? 78.901  112.416 152.138 1.00 69.60  ?  221 GLY B C   1 
ATOM   3562 O O   . GLY B 2 227 ? 79.683  112.868 152.980 1.00 69.60  ?  221 GLY B O   1 
ATOM   3563 N N   . MET B 2 228 ? 78.713  111.110 151.958 1.00 75.89  ?  222 MET B N   1 
ATOM   3564 C CA  . MET B 2 228 ? 79.411  110.112 152.758 1.00 75.89  ?  222 MET B CA  1 
ATOM   3565 C C   . MET B 2 228 ? 79.579  108.850 151.927 1.00 75.89  ?  222 MET B C   1 
ATOM   3566 O O   . MET B 2 228 ? 78.632  108.411 151.267 1.00 75.89  ?  222 MET B O   1 
ATOM   3567 C CB  . MET B 2 228 ? 78.642  109.804 154.048 1.00 75.89  ?  222 MET B CB  1 
ATOM   3568 C CG  . MET B 2 228 ? 77.230  109.286 153.820 1.00 75.89  ?  222 MET B CG  1 
ATOM   3569 S SD  . MET B 2 228 ? 76.321  109.033 155.357 1.00 75.89  ?  222 MET B SD  1 
ATOM   3570 C CE  . MET B 2 228 ? 74.767  108.398 154.733 1.00 75.89  ?  222 MET B CE  1 
ATOM   3571 N N   . CYS B 2 229 ? 80.779  108.275 151.960 1.00 76.03  ?  223 CYS B N   1 
ATOM   3572 C CA  . CYS B 2 229 ? 81.070  107.058 151.210 1.00 76.03  ?  223 CYS B CA  1 
ATOM   3573 C C   . CYS B 2 229 ? 80.565  105.858 152.002 1.00 76.03  ?  223 CYS B C   1 
ATOM   3574 O O   . CYS B 2 229 ? 81.128  105.508 153.044 1.00 76.03  ?  223 CYS B O   1 
ATOM   3575 C CB  . CYS B 2 229 ? 82.566  106.949 150.926 1.00 76.03  ?  223 CYS B CB  1 
ATOM   3576 S SG  . CYS B 2 229 ? 83.629  107.103 152.380 1.00 76.03  ?  223 CYS B SG  1 
ATOM   3577 N N   . ARG B 2 230 ? 79.495  105.228 151.510 1.00 76.13  ?  224 ARG B N   1 
ATOM   3578 C CA  . ARG B 2 230 ? 78.915  104.094 152.221 1.00 76.13  ?  224 ARG B CA  1 
ATOM   3579 C C   . ARG B 2 230 ? 79.868  102.907 152.261 1.00 76.13  ?  224 ARG B C   1 
ATOM   3580 O O   . ARG B 2 230 ? 79.841  102.123 153.217 1.00 76.13  ?  224 ARG B O   1 
ATOM   3581 C CB  . ARG B 2 230 ? 77.592  103.690 151.569 1.00 76.13  ?  224 ARG B CB  1 
ATOM   3582 C CG  . ARG B 2 230 ? 76.555  104.802 151.544 1.00 76.13  ?  224 ARG B CG  1 
ATOM   3583 C CD  . ARG B 2 230 ? 75.257  104.343 150.899 1.00 76.13  ?  224 ARG B CD  1 
ATOM   3584 N NE  . ARG B 2 230 ? 74.632  103.249 151.638 1.00 76.13  ?  224 ARG B NE  1 
ATOM   3585 C CZ  . ARG B 2 230 ? 73.476  102.682 151.304 1.00 76.13  ?  224 ARG B CZ  1 
ATOM   3586 N NH1 . ARG B 2 230 ? 72.807  103.103 150.239 1.00 76.13  1  224 ARG B NH1 1 
ATOM   3587 N NH2 . ARG B 2 230 ? 72.987  101.693 152.038 1.00 76.13  ?  224 ARG B NH2 1 
ATOM   3588 N N   . GLN B 2 231 ? 80.712  102.757 151.243 1.00 75.35  ?  225 GLN B N   1 
ATOM   3589 C CA  . GLN B 2 231 ? 81.668  101.662 151.181 1.00 75.35  ?  225 GLN B CA  1 
ATOM   3590 C C   . GLN B 2 231 ? 82.989  102.178 150.633 1.00 75.35  ?  225 GLN B C   1 
ATOM   3591 O O   . GLN B 2 231 ? 83.025  103.126 149.843 1.00 75.35  ?  225 GLN B O   1 
ATOM   3592 C CB  . GLN B 2 231 ? 81.152  100.509 150.308 1.00 75.35  ?  225 GLN B CB  1 
ATOM   3593 C CG  . GLN B 2 231 ? 79.883  99.858  150.834 1.00 75.35  ?  225 GLN B CG  1 
ATOM   3594 C CD  . GLN B 2 231 ? 79.418  98.703  149.969 1.00 75.35  ?  225 GLN B CD  1 
ATOM   3595 O OE1 . GLN B 2 231 ? 80.010  98.415  148.928 1.00 75.35  ?  225 GLN B OE1 1 
ATOM   3596 N NE2 . GLN B 2 231 ? 78.354  98.034  150.396 1.00 75.35  ?  225 GLN B NE2 1 
ATOM   3597 N N   . THR B 2 232 ? 84.078  101.539 151.060 1.00 74.78  ?  226 THR B N   1 
ATOM   3598 C CA  . THR B 2 232 ? 85.429  101.934 150.658 1.00 74.78  ?  226 THR B CA  1 
ATOM   3599 C C   . THR B 2 232 ? 86.239  100.663 150.422 1.00 74.78  ?  226 THR B C   1 
ATOM   3600 O O   . THR B 2 232 ? 86.723  100.041 151.373 1.00 74.78  ?  226 THR B O   1 
ATOM   3601 C CB  . THR B 2 232 ? 86.084  102.819 151.713 1.00 74.78  ?  226 THR B CB  1 
ATOM   3602 O OG1 . THR B 2 232 ? 85.291  103.997 151.914 1.00 74.78  ?  226 THR B OG1 1 
ATOM   3603 C CG2 . THR B 2 232 ? 87.488  103.223 151.280 1.00 74.78  ?  226 THR B CG2 1 
ATOM   3604 N N   . PHE B 2 233 ? 86.447  100.303 149.161 1.00 71.93  ?  227 PHE B N   1 
ATOM   3605 C CA  . PHE B 2 233 ? 87.156  99.081  148.832 1.00 71.93  ?  227 PHE B CA  1 
ATOM   3606 C C   . PHE B 2 233 ? 88.592  99.516  148.873 1.00 71.93  ?  227 PHE B C   1 
ATOM   3607 O O   . PHE B 2 233 ? 88.871  100.634 148.498 1.00 71.93  ?  227 PHE B O   1 
ATOM   3608 C CB  . PHE B 2 233 ? 86.759  98.609  147.437 1.00 71.93  ?  227 PHE B CB  1 
ATOM   3609 C CG  . PHE B 2 233 ? 85.290  98.303  147.301 1.00 71.93  ?  227 PHE B CG  1 
ATOM   3610 C CD1 . PHE B 2 233 ? 84.350  99.314  147.121 1.00 71.93  ?  227 PHE B CD1 1 
ATOM   3611 C CD2 . PHE B 2 233 ? 84.846  97.004  147.371 1.00 71.93  ?  227 PHE B CD2 1 
ATOM   3612 C CE1 . PHE B 2 233 ? 83.010  99.024  147.008 1.00 71.93  ?  227 PHE B CE1 1 
ATOM   3613 C CE2 . PHE B 2 233 ? 83.512  96.713  147.249 1.00 71.93  ?  227 PHE B CE2 1 
ATOM   3614 C CZ  . PHE B 2 233 ? 82.590  97.718  147.067 1.00 71.93  ?  227 PHE B CZ  1 
ATOM   3615 N N   . THR B 2 234 ? 89.487  98.676  149.376 1.00 73.00  ?  228 THR B N   1 
ATOM   3616 C CA  . THR B 2 234 ? 90.898  99.019  149.474 1.00 73.00  ?  228 THR B CA  1 
ATOM   3617 C C   . THR B 2 234 ? 91.663  97.839  148.921 1.00 73.00  ?  228 THR B C   1 
ATOM   3618 O O   . THR B 2 234 ? 92.405  97.180  149.651 1.00 73.00  ?  228 THR B O   1 
ATOM   3619 C CB  . THR B 2 234 ? 91.288  99.319  150.939 1.00 73.00  ?  228 THR B CB  1 
ATOM   3620 O OG1 . THR B 2 234 ? 90.816  98.270  151.797 1.00 73.00  ?  228 THR B OG1 1 
ATOM   3621 C CG2 . THR B 2 234 ? 90.664  100.627 151.409 1.00 73.00  ?  228 THR B CG2 1 
ATOM   3622 N N   . GLY B 2 235 ? 91.477  97.567  147.632 1.00 67.99  ?  229 GLY B N   1 
ATOM   3623 C CA  . GLY B 2 235 ? 92.135  96.440  146.994 1.00 67.99  ?  229 GLY B CA  1 
ATOM   3624 C C   . GLY B 2 235 ? 92.722  96.749  145.642 1.00 67.99  ?  229 GLY B C   1 
ATOM   3625 O O   . GLY B 2 235 ? 92.079  96.451  144.650 1.00 67.99  ?  229 GLY B O   1 
ATOM   3626 N N   . HIS B 2 236 ? 93.880  97.392  145.566 1.00 67.22  ?  230 HIS B N   1 
ATOM   3627 C CA  . HIS B 2 236 ? 94.523  97.576  144.260 1.00 67.22  ?  230 HIS B CA  1 
ATOM   3628 C C   . HIS B 2 236 ? 96.035  97.638  144.321 1.00 67.22  ?  230 HIS B C   1 
ATOM   3629 O O   . HIS B 2 236 ? 96.608  98.070  145.316 1.00 67.22  ?  230 HIS B O   1 
ATOM   3630 C CB  . HIS B 2 236 ? 93.961  98.793  143.518 1.00 67.22  ?  230 HIS B CB  1 
ATOM   3631 C CG  . HIS B 2 236 ? 93.197  98.429  142.283 1.00 67.22  ?  230 HIS B CG  1 
ATOM   3632 N ND1 . HIS B 2 236 ? 93.816  98.086  141.100 1.00 67.22  ?  230 HIS B ND1 1 
ATOM   3633 C CD2 . HIS B 2 236 ? 91.866  98.327  142.054 1.00 67.22  ?  230 HIS B CD2 1 
ATOM   3634 C CE1 . HIS B 2 236 ? 92.899  97.799  140.193 1.00 67.22  ?  230 HIS B CE1 1 
ATOM   3635 N NE2 . HIS B 2 236 ? 91.709  97.937  140.746 1.00 67.22  ?  230 HIS B NE2 1 
ATOM   3636 N N   . GLU B 2 237 ? 96.691  97.128  143.292 1.00 69.43  ?  231 GLU B N   1 
ATOM   3637 C CA  . GLU B 2 237 ? 98.147  97.221  143.217 1.00 69.43  ?  231 GLU B CA  1 
ATOM   3638 C C   . GLU B 2 237 ? 98.674  98.621  142.946 1.00 69.43  ?  231 GLU B C   1 
ATOM   3639 O O   . GLU B 2 237 ? 99.701  98.994  143.513 1.00 69.43  ?  231 GLU B O   1 
ATOM   3640 C CB  . GLU B 2 237 ? 98.680  96.267  142.158 1.00 69.43  ?  231 GLU B CB  1 
ATOM   3641 C CG  . GLU B 2 237 ? 98.334  94.802  142.410 1.00 69.43  ?  231 GLU B CG  1 
ATOM   3642 C CD  . GLU B 2 237 ? 99.484  93.844  142.149 1.00 69.43  ?  231 GLU B CD  1 
ATOM   3643 O OE1 . GLU B 2 237 ? 100.603 94.081  142.651 1.00 69.43  ?  231 GLU B OE1 1 
ATOM   3644 O OE2 . GLU B 2 237 ? 99.257  92.832  141.454 1.00 69.43  ?  231 GLU B OE2 1 
ATOM   3645 N N   . SER B 2 238 ? 97.998  99.390  142.086 1.00 66.78  ?  232 SER B N   1 
ATOM   3646 C CA  . SER B 2 238 ? 98.518  100.703 141.663 1.00 66.78  ?  232 SER B CA  1 
ATOM   3647 C C   . SER B 2 238 ? 97.445  101.797 141.535 1.00 66.78  ?  232 SER B C   1 
ATOM   3648 O O   . SER B 2 238 ? 96.390  101.667 142.161 1.00 66.78  ?  232 SER B O   1 
ATOM   3649 C CB  . SER B 2 238 ? 99.237  100.487 140.337 1.00 66.78  ?  232 SER B CB  1 
ATOM   3650 O OG  . SER B 2 238 ? 98.288  100.296 139.311 1.00 66.78  ?  232 SER B OG  1 
ATOM   3651 N N   . ASP B 2 239 ? 97.676  102.853 140.731 1.00 64.49  ?  233 ASP B N   1 
ATOM   3652 C CA  . ASP B 2 239 ? 96.734  103.963 140.683 1.00 64.49  ?  233 ASP B CA  1 
ATOM   3653 C C   . ASP B 2 239 ? 95.599  103.638 139.720 1.00 64.49  ?  233 ASP B C   1 
ATOM   3654 O O   . ASP B 2 239 ? 95.838  103.343 138.545 1.00 64.49  ?  233 ASP B O   1 
ATOM   3655 C CB  . ASP B 2 239 ? 97.440  105.249 140.252 1.00 64.49  ?  233 ASP B CB  1 
ATOM   3656 C CG  . ASP B 2 239 ? 98.618  105.594 141.143 1.00 64.49  ?  233 ASP B CG  1 
ATOM   3657 O OD1 . ASP B 2 239 ? 98.619  105.177 142.320 1.00 64.49  ?  233 ASP B OD1 1 
ATOM   3658 O OD2 . ASP B 2 239 ? 99.543  106.283 140.665 1.00 64.49  ?  233 ASP B OD2 1 
ATOM   3659 N N   . ILE B 2 240 ? 94.369  103.700 140.221 1.00 63.57  ?  234 ILE B N   1 
ATOM   3660 C CA  . ILE B 2 240 ? 93.194  103.416 139.405 1.00 63.57  ?  234 ILE B CA  1 
ATOM   3661 C C   . ILE B 2 240 ? 93.038  104.518 138.367 1.00 63.57  ?  234 ILE B C   1 
ATOM   3662 O O   . ILE B 2 240 ? 93.124  105.709 138.689 1.00 63.57  ?  234 ILE B O   1 
ATOM   3663 C CB  . ILE B 2 240 ? 91.938  103.295 140.282 1.00 63.57  ?  234 ILE B CB  1 
ATOM   3664 C CG1 . ILE B 2 240 ? 92.102  102.152 141.288 1.00 63.57  ?  234 ILE B CG1 1 
ATOM   3665 C CG2 . ILE B 2 240 ? 90.701  103.076 139.413 1.00 63.57  ?  234 ILE B CG2 1 
ATOM   3666 C CD1 . ILE B 2 240 ? 90.977  102.049 142.299 1.00 63.57  ?  234 ILE B CD1 1 
ATOM   3667 N N   . ASN B 2 241 ? 92.809  104.122 137.113 1.00 63.88  ?  235 ASN B N   1 
ATOM   3668 C CA  . ASN B 2 241 ? 92.651  105.064 136.017 1.00 63.88  ?  235 ASN B CA  1 
ATOM   3669 C C   . ASN B 2 241 ? 91.279  105.023 135.363 1.00 63.88  ?  235 ASN B C   1 
ATOM   3670 O O   . ASN B 2 241 ? 90.952  105.943 134.604 1.00 63.88  ?  235 ASN B O   1 
ATOM   3671 C CB  . ASN B 2 241 ? 93.717  104.813 134.938 1.00 63.88  ?  235 ASN B CB  1 
ATOM   3672 C CG  . ASN B 2 241 ? 95.124  105.075 135.436 1.00 63.88  ?  235 ASN B CG  1 
ATOM   3673 O OD1 . ASN B 2 241 ? 95.330  105.856 136.365 1.00 63.88  ?  235 ASN B OD1 1 
ATOM   3674 N ND2 . ASN B 2 241 ? 96.102  104.426 134.816 1.00 63.88  ?  235 ASN B ND2 1 
ATOM   3675 N N   . ALA B 2 242 ? 90.469  104.000 135.627 1.00 62.96  ?  236 ALA B N   1 
ATOM   3676 C CA  . ALA B 2 242 ? 89.143  103.919 135.034 1.00 62.96  ?  236 ALA B CA  1 
ATOM   3677 C C   . ALA B 2 242 ? 88.224  103.139 135.961 1.00 62.96  ?  236 ALA B C   1 
ATOM   3678 O O   . ALA B 2 242 ? 88.663  102.267 136.714 1.00 62.96  ?  236 ALA B O   1 
ATOM   3679 C CB  . ALA B 2 242 ? 89.186  103.263 133.650 1.00 62.96  ?  236 ALA B CB  1 
ATOM   3680 N N   . ILE B 2 243 ? 86.935  103.454 135.883 1.00 63.92  ?  237 ILE B N   1 
ATOM   3681 C CA  . ILE B 2 243 ? 85.931  102.787 136.703 1.00 63.92  ?  237 ILE B CA  1 
ATOM   3682 C C   . ILE B 2 243 ? 84.610  102.826 135.950 1.00 63.92  ?  237 ILE B C   1 
ATOM   3683 O O   . ILE B 2 243 ? 84.274  103.824 135.308 1.00 63.92  ?  237 ILE B O   1 
ATOM   3684 C CB  . ILE B 2 243 ? 85.817  103.448 138.097 1.00 63.92  ?  237 ILE B CB  1 
ATOM   3685 C CG1 . ILE B 2 243 ? 84.995  102.568 139.037 1.00 63.92  ?  237 ILE B CG1 1 
ATOM   3686 C CG2 . ILE B 2 243 ? 85.184  104.827 137.985 1.00 63.92  ?  237 ILE B CG2 1 
ATOM   3687 C CD1 . ILE B 2 243 ? 85.205  102.889 140.498 1.00 63.92  ?  237 ILE B CD1 1 
ATOM   3688 N N   . CYS B 2 244 ? 83.864  101.727 136.032 1.00 66.37  ?  238 CYS B N   1 
ATOM   3689 C CA  . CYS B 2 244 ? 82.588  101.621 135.341 1.00 66.37  ?  238 CYS B CA  1 
ATOM   3690 C C   . CYS B 2 244 ? 81.600  100.874 136.223 1.00 66.37  ?  238 CYS B C   1 
ATOM   3691 O O   . CYS B 2 244 ? 81.974  99.961  136.963 1.00 66.37  ?  238 CYS B O   1 
ATOM   3692 C CB  . CYS B 2 244 ? 82.733  100.909 133.992 1.00 66.37  ?  238 CYS B CB  1 
ATOM   3693 S SG  . CYS B 2 244 ? 81.183  100.739 133.080 1.00 66.37  ?  238 CYS B SG  1 
ATOM   3694 N N   . PHE B 2 245 ? 80.335  101.274 136.138 1.00 66.24  ?  239 PHE B N   1 
ATOM   3695 C CA  . PHE B 2 245 ? 79.277  100.666 136.929 1.00 66.24  ?  239 PHE B CA  1 
ATOM   3696 C C   . PHE B 2 245 ? 78.589  99.557  136.142 1.00 66.24  ?  239 PHE B C   1 
ATOM   3697 O O   . PHE B 2 245 ? 78.408  99.651  134.925 1.00 66.24  ?  239 PHE B O   1 
ATOM   3698 C CB  . PHE B 2 245 ? 78.247  101.715 137.350 1.00 66.24  ?  239 PHE B CB  1 
ATOM   3699 C CG  . PHE B 2 245 ? 77.969  101.734 138.825 1.00 66.24  ?  239 PHE B CG  1 
ATOM   3700 C CD1 . PHE B 2 245 ? 77.174  100.762 139.407 1.00 66.24  ?  239 PHE B CD1 1 
ATOM   3701 C CD2 . PHE B 2 245 ? 78.501  102.728 139.630 1.00 66.24  ?  239 PHE B CD2 1 
ATOM   3702 C CE1 . PHE B 2 245 ? 76.917  100.778 140.764 1.00 66.24  ?  239 PHE B CE1 1 
ATOM   3703 C CE2 . PHE B 2 245 ? 78.246  102.749 140.988 1.00 66.24  ?  239 PHE B CE2 1 
ATOM   3704 C CZ  . PHE B 2 245 ? 77.453  101.773 141.555 1.00 66.24  ?  239 PHE B CZ  1 
ATOM   3705 N N   . PHE B 2 246 ? 78.201  98.505  136.854 1.00 68.76  ?  240 PHE B N   1 
ATOM   3706 C CA  . PHE B 2 246 ? 77.517  97.393  136.213 1.00 68.76  ?  240 PHE B CA  1 
ATOM   3707 C C   . PHE B 2 246 ? 76.106  97.822  135.808 1.00 68.76  ?  240 PHE B C   1 
ATOM   3708 O O   . PHE B 2 246 ? 75.473  98.612  136.515 1.00 68.76  ?  240 PHE B O   1 
ATOM   3709 C CB  . PHE B 2 246 ? 77.455  96.192  137.156 1.00 68.76  ?  240 PHE B CB  1 
ATOM   3710 C CG  . PHE B 2 246 ? 77.408  94.866  136.452 1.00 68.76  ?  240 PHE B CG  1 
ATOM   3711 C CD1 . PHE B 2 246 ? 78.564  94.297  135.945 1.00 68.76  ?  240 PHE B CD1 1 
ATOM   3712 C CD2 . PHE B 2 246 ? 76.212  94.184  136.306 1.00 68.76  ?  240 PHE B CD2 1 
ATOM   3713 C CE1 . PHE B 2 246 ? 78.527  93.077  135.298 1.00 68.76  ?  240 PHE B CE1 1 
ATOM   3714 C CE2 . PHE B 2 246 ? 76.169  92.963  135.660 1.00 68.76  ?  240 PHE B CE2 1 
ATOM   3715 C CZ  . PHE B 2 246 ? 77.328  92.409  135.156 1.00 68.76  ?  240 PHE B CZ  1 
ATOM   3716 N N   . PRO B 2 247 ? 75.589  97.331  134.677 1.00 67.71  ?  241 PRO B N   1 
ATOM   3717 C CA  . PRO B 2 247 ? 74.248  97.760  134.243 1.00 67.71  ?  241 PRO B CA  1 
ATOM   3718 C C   . PRO B 2 247 ? 73.176  97.633  135.312 1.00 67.71  ?  241 PRO B C   1 
ATOM   3719 O O   . PRO B 2 247 ? 72.215  98.414  135.305 1.00 67.71  ?  241 PRO B O   1 
ATOM   3720 C CB  . PRO B 2 247 ? 73.965  96.839  133.050 1.00 67.71  ?  241 PRO B CB  1 
ATOM   3721 C CG  . PRO B 2 247 ? 75.307  96.533  132.495 1.00 67.71  ?  241 PRO B CG  1 
ATOM   3722 C CD  . PRO B 2 247 ? 76.237  96.465  133.674 1.00 67.71  ?  241 PRO B CD  1 
ATOM   3723 N N   . ASN B 2 248 ? 73.304  96.677  136.235 1.00 70.33  ?  242 ASN B N   1 
ATOM   3724 C CA  . ASN B 2 248 ? 72.297  96.522  137.280 1.00 70.33  ?  242 ASN B CA  1 
ATOM   3725 C C   . ASN B 2 248 ? 72.523  97.483  138.440 1.00 70.33  ?  242 ASN B C   1 
ATOM   3726 O O   . ASN B 2 248 ? 71.553  97.962  139.038 1.00 70.33  ?  242 ASN B O   1 
ATOM   3727 C CB  . ASN B 2 248 ? 72.284  95.080  137.793 1.00 70.33  ?  242 ASN B CB  1 
ATOM   3728 C CG  . ASN B 2 248 ? 73.623  94.646  138.358 1.00 70.33  ?  242 ASN B CG  1 
ATOM   3729 O OD1 . ASN B 2 248 ? 74.464  95.473  138.710 1.00 70.33  ?  242 ASN B OD1 1 
ATOM   3730 N ND2 . ASN B 2 248 ? 73.828  93.337  138.444 1.00 70.33  ?  242 ASN B ND2 1 
ATOM   3731 N N   . GLY B 2 249 ? 73.780  97.774  138.769 1.00 69.27  ?  243 GLY B N   1 
ATOM   3732 C CA  . GLY B 2 249 ? 74.109  98.669  139.858 1.00 69.27  ?  243 GLY B CA  1 
ATOM   3733 C C   . GLY B 2 249 ? 74.580  97.990  141.125 1.00 69.27  ?  243 GLY B C   1 
ATOM   3734 O O   . GLY B 2 249 ? 74.794  98.678  142.130 1.00 69.27  ?  243 GLY B O   1 
ATOM   3735 N N   . ASN B 2 250 ? 74.749  96.668  141.113 1.00 72.34  ?  244 ASN B N   1 
ATOM   3736 C CA  . ASN B 2 250 ? 75.195  95.933  142.287 1.00 72.34  ?  244 ASN B CA  1 
ATOM   3737 C C   . ASN B 2 250 ? 76.699  95.693  142.307 1.00 72.34  ?  244 ASN B C   1 
ATOM   3738 O O   . ASN B 2 250 ? 77.233  95.299  143.350 1.00 72.34  ?  244 ASN B O   1 
ATOM   3739 C CB  . ASN B 2 250 ? 74.470  94.585  142.370 1.00 72.34  ?  244 ASN B CB  1 
ATOM   3740 C CG  . ASN B 2 250 ? 72.966  94.738  142.481 1.00 72.34  ?  244 ASN B CG  1 
ATOM   3741 O OD1 . ASN B 2 250 ? 72.470  95.722  143.029 1.00 72.34  ?  244 ASN B OD1 1 
ATOM   3742 N ND2 . ASN B 2 250 ? 72.232  93.762  141.959 1.00 72.34  ?  244 ASN B ND2 1 
ATOM   3743 N N   . ALA B 2 251 ? 77.392  95.918  141.192 1.00 70.13  ?  245 ALA B N   1 
ATOM   3744 C CA  . ALA B 2 251 ? 78.829  95.707  141.106 1.00 70.13  ?  245 ALA B CA  1 
ATOM   3745 C C   . ALA B 2 251 ? 79.431  96.798  140.229 1.00 70.13  ?  245 ALA B C   1 
ATOM   3746 O O   . ALA B 2 251 ? 78.718  97.626  139.653 1.00 70.13  ?  245 ALA B O   1 
ATOM   3747 C CB  . ALA B 2 251 ? 79.152  94.312  140.559 1.00 70.13  ?  245 ALA B CB  1 
ATOM   3748 N N   . PHE B 2 252 ? 80.759  96.798  140.132 1.00 68.17  ?  246 PHE B N   1 
ATOM   3749 C CA  . PHE B 2 252 ? 81.456  97.789  139.324 1.00 68.17  ?  246 PHE B CA  1 
ATOM   3750 C C   . PHE B 2 252 ? 82.889  97.334  139.097 1.00 68.17  ?  246 PHE B C   1 
ATOM   3751 O O   . PHE B 2 252 ? 83.501  96.730  139.980 1.00 68.17  ?  246 PHE B O   1 
ATOM   3752 C CB  . PHE B 2 252 ? 81.437  99.168  139.998 1.00 68.17  ?  246 PHE B CB  1 
ATOM   3753 C CG  . PHE B 2 252 ? 82.234  99.235  141.269 1.00 68.17  ?  246 PHE B CG  1 
ATOM   3754 C CD1 . PHE B 2 252 ? 81.665  98.876  142.479 1.00 68.17  ?  246 PHE B CD1 1 
ATOM   3755 C CD2 . PHE B 2 252 ? 83.550  99.664  141.254 1.00 68.17  ?  246 PHE B CD2 1 
ATOM   3756 C CE1 . PHE B 2 252 ? 82.397  98.940  143.649 1.00 68.17  ?  246 PHE B CE1 1 
ATOM   3757 C CE2 . PHE B 2 252 ? 84.286  99.730  142.421 1.00 68.17  ?  246 PHE B CE2 1 
ATOM   3758 C CZ  . PHE B 2 252 ? 83.708  99.369  143.619 1.00 68.17  ?  246 PHE B CZ  1 
ATOM   3759 N N   . ALA B 2 253 ? 83.418  97.645  137.917 1.00 66.02  ?  247 ALA B N   1 
ATOM   3760 C CA  . ALA B 2 253 ? 84.772  97.271  137.537 1.00 66.02  ?  247 ALA B CA  1 
ATOM   3761 C C   . ALA B 2 253 ? 85.712  98.460  137.680 1.00 66.02  ?  247 ALA B C   1 
ATOM   3762 O O   . ALA B 2 253 ? 85.334  99.604  137.402 1.00 66.02  ?  247 ALA B O   1 
ATOM   3763 C CB  . ALA B 2 253 ? 84.811  96.749  136.100 1.00 66.02  ?  247 ALA B CB  1 
ATOM   3764 N N   . THR B 2 254 ? 86.939  98.179  138.114 1.00 66.45  ?  248 THR B N   1 
ATOM   3765 C CA  . THR B 2 254 ? 87.981  99.181  138.286 1.00 66.45  ?  248 THR B CA  1 
ATOM   3766 C C   . THR B 2 254 ? 89.233  98.723  137.553 1.00 66.45  ?  248 THR B C   1 
ATOM   3767 O O   . THR B 2 254 ? 89.641  97.563  137.679 1.00 66.45  ?  248 THR B O   1 
ATOM   3768 C CB  . THR B 2 254 ? 88.300  99.406  139.769 1.00 66.45  ?  248 THR B CB  1 
ATOM   3769 O OG1 . THR B 2 254 ? 88.890  98.221  140.318 1.00 66.45  ?  248 THR B OG1 1 
ATOM   3770 C CG2 . THR B 2 254 ? 87.038  99.746  140.548 1.00 66.45  ?  248 THR B CG2 1 
ATOM   3771 N N   . GLY B 2 255 ? 89.838  99.631  136.800 1.00 64.95  ?  249 GLY B N   1 
ATOM   3772 C CA  . GLY B 2 255 ? 91.058  99.343  136.059 1.00 64.95  ?  249 GLY B CA  1 
ATOM   3773 C C   . GLY B 2 255 ? 92.134  100.359 136.383 1.00 64.95  ?  249 GLY B C   1 
ATOM   3774 O O   . GLY B 2 255 ? 91.876  101.566 136.394 1.00 64.95  ?  249 GLY B O   1 
ATOM   3775 N N   . SER B 2 256 ? 93.341  99.862  136.646 1.00 65.82  ?  250 SER B N   1 
ATOM   3776 C CA  . SER B 2 256 ? 94.483  100.687 137.012 1.00 65.82  ?  250 SER B CA  1 
ATOM   3777 C C   . SER B 2 256 ? 95.595  100.480 135.989 1.00 65.82  ?  250 SER B C   1 
ATOM   3778 O O   . SER B 2 256 ? 95.431  99.767  134.994 1.00 65.82  ?  250 SER B O   1 
ATOM   3779 C CB  . SER B 2 256 ? 94.968  100.355 138.429 1.00 65.82  ?  250 SER B CB  1 
ATOM   3780 O OG  . SER B 2 256 ? 95.358  98.997  138.530 1.00 65.82  ?  250 SER B OG  1 
ATOM   3781 N N   . ASP B 2 257 ? 96.739  101.113 136.240 1.00 66.18  ?  251 ASP B N   1 
ATOM   3782 C CA  . ASP B 2 257 ? 97.885  101.036 135.343 1.00 66.18  ?  251 ASP B CA  1 
ATOM   3783 C C   . ASP B 2 257 ? 98.673  99.739  135.492 1.00 66.18  ?  251 ASP B C   1 
ATOM   3784 O O   . ASP B 2 257 ? 99.713  99.589  134.842 1.00 66.18  ?  251 ASP B O   1 
ATOM   3785 C CB  . ASP B 2 257 ? 98.814  102.230 135.577 1.00 66.18  ?  251 ASP B CB  1 
ATOM   3786 C CG  . ASP B 2 257 ? 99.380  102.262 136.984 1.00 66.18  ?  251 ASP B CG  1 
ATOM   3787 O OD1 . ASP B 2 257 ? 100.258 101.430 137.293 1.00 66.18  ?  251 ASP B OD1 1 
ATOM   3788 O OD2 . ASP B 2 257 ? 98.947  103.121 137.781 1.00 66.18  ?  251 ASP B OD2 1 
ATOM   3789 N N   . ASP B 2 258 ? 98.211  98.807  136.322 1.00 66.85  ?  252 ASP B N   1 
ATOM   3790 C CA  . ASP B 2 258 ? 98.889  97.534  136.523 1.00 66.85  ?  252 ASP B CA  1 
ATOM   3791 C C   . ASP B 2 258 ? 98.441  96.469  135.528 1.00 66.85  ?  252 ASP B C   1 
ATOM   3792 O O   . ASP B 2 258 ? 98.816  95.302  135.676 1.00 66.85  ?  252 ASP B O   1 
ATOM   3793 C CB  . ASP B 2 258 ? 98.660  97.038  137.954 1.00 66.85  ?  252 ASP B CB  1 
ATOM   3794 C CG  . ASP B 2 258 ? 99.602  95.915  138.345 1.00 66.85  ?  252 ASP B CG  1 
ATOM   3795 O OD1 . ASP B 2 258 ? 100.541 95.624  137.573 1.00 66.85  ?  252 ASP B OD1 1 
ATOM   3796 O OD2 . ASP B 2 258 ? 99.403  95.321  139.425 1.00 66.85  ?  252 ASP B OD2 1 
ATOM   3797 N N   . ALA B 2 259 ? 97.649  96.843  134.522 1.00 66.71  ?  253 ALA B N   1 
ATOM   3798 C CA  . ALA B 2 259 ? 97.180  95.915  133.496 1.00 66.71  ?  253 ALA B CA  1 
ATOM   3799 C C   . ALA B 2 259 ? 96.282  94.828  134.078 1.00 66.71  ?  253 ALA B C   1 
ATOM   3800 O O   . ALA B 2 259 ? 96.265  93.699  133.582 1.00 66.71  ?  253 ALA B O   1 
ATOM   3801 C CB  . ALA B 2 259 ? 98.355  95.280  132.746 1.00 66.71  ?  253 ALA B CB  1 
ATOM   3802 N N   . THR B 2 260 ? 95.532  95.152  135.129 1.00 66.15  ?  254 THR B N   1 
ATOM   3803 C CA  . THR B 2 260 ? 94.651  94.192  135.780 1.00 66.15  ?  254 THR B CA  1 
ATOM   3804 C C   . THR B 2 260 ? 93.374  94.892  136.215 1.00 66.15  ?  254 THR B C   1 
ATOM   3805 O O   . THR B 2 260 ? 93.427  95.888  136.943 1.00 66.15  ?  254 THR B O   1 
ATOM   3806 C CB  . THR B 2 260 ? 95.330  93.546  136.995 1.00 66.15  ?  254 THR B CB  1 
ATOM   3807 O OG1 . THR B 2 260 ? 95.594  94.546  137.987 1.00 66.15  ?  254 THR B OG1 1 
ATOM   3808 C CG2 . THR B 2 260 ? 96.637  92.882  136.590 1.00 66.15  ?  254 THR B CG2 1 
ATOM   3809 N N   . CYS B 2 261 ? 92.235  94.372  135.770 1.00 66.33  ?  255 CYS B N   1 
ATOM   3810 C CA  . CYS B 2 261 ? 90.937  94.874  136.189 1.00 66.33  ?  255 CYS B CA  1 
ATOM   3811 C C   . CYS B 2 261 ? 90.411  94.056  137.364 1.00 66.33  ?  255 CYS B C   1 
ATOM   3812 O O   . CYS B 2 261 ? 90.770  92.892  137.554 1.00 66.33  ?  255 CYS B O   1 
ATOM   3813 C CB  . CYS B 2 261 ? 89.936  94.826  135.033 1.00 66.33  ?  255 CYS B CB  1 
ATOM   3814 S SG  . CYS B 2 261 ? 90.323  95.932  133.659 1.00 66.33  ?  255 CYS B SG  1 
ATOM   3815 N N   . ARG B 2 262 ? 89.548  94.686  138.158 1.00 68.32  ?  256 ARG B N   1 
ATOM   3816 C CA  . ARG B 2 262 ? 88.957  94.033  139.319 1.00 68.32  ?  256 ARG B CA  1 
ATOM   3817 C C   . ARG B 2 262 ? 87.487  94.406  139.414 1.00 68.32  ?  256 ARG B C   1 
ATOM   3818 O O   . ARG B 2 262 ? 87.141  95.590  139.382 1.00 68.32  ?  256 ARG B O   1 
ATOM   3819 C CB  . ARG B 2 262 ? 89.693  94.422  140.607 1.00 68.32  ?  256 ARG B CB  1 
ATOM   3820 C CG  . ARG B 2 262 ? 91.166  94.042  140.602 1.00 68.32  ?  256 ARG B CG  1 
ATOM   3821 C CD  . ARG B 2 262 ? 91.800  94.215  141.972 1.00 68.32  ?  256 ARG B CD  1 
ATOM   3822 N NE  . ARG B 2 262 ? 93.212  93.839  141.968 1.00 68.32  ?  256 ARG B NE  1 
ATOM   3823 C CZ  . ARG B 2 262 ? 93.977  93.781  143.053 1.00 68.32  ?  256 ARG B CZ  1 
ATOM   3824 N NH1 . ARG B 2 262 ? 93.473  94.071  144.245 1.00 68.32  1  256 ARG B NH1 1 
ATOM   3825 N NH2 . ARG B 2 262 ? 95.251  93.428  142.947 1.00 68.32  ?  256 ARG B NH2 1 
ATOM   3826 N N   . LEU B 2 263 ? 86.630  93.394  139.528 1.00 70.46  ?  257 LEU B N   1 
ATOM   3827 C CA  . LEU B 2 263 ? 85.183  93.581  139.605 1.00 70.46  ?  257 LEU B CA  1 
ATOM   3828 C C   . LEU B 2 263 ? 84.766  93.479  141.068 1.00 70.46  ?  257 LEU B C   1 
ATOM   3829 O O   . LEU B 2 263 ? 84.671  92.382  141.623 1.00 70.46  ?  257 LEU B O   1 
ATOM   3830 C CB  . LEU B 2 263 ? 84.461  92.548  138.744 1.00 70.46  ?  257 LEU B CB  1 
ATOM   3831 C CG  . LEU B 2 263 ? 82.932  92.562  138.798 1.00 70.46  ?  257 LEU B CG  1 
ATOM   3832 C CD1 . LEU B 2 263 ? 82.383  93.897  138.322 1.00 70.46  ?  257 LEU B CD1 1 
ATOM   3833 C CD2 . LEU B 2 263 ? 82.361  91.420  137.971 1.00 70.46  ?  257 LEU B CD2 1 
ATOM   3834 N N   . PHE B 2 264 ? 84.517  94.627  141.691 1.00 70.71  ?  258 PHE B N   1 
ATOM   3835 C CA  . PHE B 2 264 ? 84.048  94.671  143.065 1.00 70.71  ?  258 PHE B CA  1 
ATOM   3836 C C   . PHE B 2 264 ? 82.523  94.653  143.098 1.00 70.71  ?  258 PHE B C   1 
ATOM   3837 O O   . PHE B 2 264 ? 81.852  94.984  142.118 1.00 70.71  ?  258 PHE B O   1 
ATOM   3838 C CB  . PHE B 2 264 ? 84.573  95.919  143.775 1.00 70.71  ?  258 PHE B CB  1 
ATOM   3839 C CG  . PHE B 2 264 ? 86.071  95.978  143.870 1.00 70.71  ?  258 PHE B CG  1 
ATOM   3840 C CD1 . PHE B 2 264 ? 86.726  95.498  144.991 1.00 70.71  ?  258 PHE B CD1 1 
ATOM   3841 C CD2 . PHE B 2 264 ? 86.823  96.515  142.839 1.00 70.71  ?  258 PHE B CD2 1 
ATOM   3842 C CE1 . PHE B 2 264 ? 88.103  95.552  145.082 1.00 70.71  ?  258 PHE B CE1 1 
ATOM   3843 C CE2 . PHE B 2 264 ? 88.201  96.571  142.925 1.00 70.71  ?  258 PHE B CE2 1 
ATOM   3844 C CZ  . PHE B 2 264 ? 88.841  96.089  144.047 1.00 70.71  ?  258 PHE B CZ  1 
ATOM   3845 N N   . ASP B 2 265 ? 81.981  94.260  144.249 1.00 74.38  ?  259 ASP B N   1 
ATOM   3846 C CA  . ASP B 2 265 ? 80.543  94.142  144.439 1.00 74.38  ?  259 ASP B CA  1 
ATOM   3847 C C   . ASP B 2 265 ? 80.115  94.982  145.633 1.00 74.38  ?  259 ASP B C   1 
ATOM   3848 O O   . ASP B 2 265 ? 80.801  95.014  146.659 1.00 74.38  ?  259 ASP B O   1 
ATOM   3849 C CB  . ASP B 2 265 ? 80.131  92.681  144.653 1.00 74.38  ?  259 ASP B CB  1 
ATOM   3850 C CG  . ASP B 2 265 ? 78.629  92.509  144.760 1.00 74.38  ?  259 ASP B CG  1 
ATOM   3851 O OD1 . ASP B 2 265 ? 77.932  92.716  143.744 1.00 74.38  ?  259 ASP B OD1 1 
ATOM   3852 O OD2 . ASP B 2 265 ? 78.146  92.164  145.858 1.00 74.38  ?  259 ASP B OD2 1 
ATOM   3853 N N   . LEU B 2 266 ? 78.975  95.662  145.492 1.00 71.73  ?  260 LEU B N   1 
ATOM   3854 C CA  . LEU B 2 266 ? 78.464  96.492  146.576 1.00 71.73  ?  260 LEU B CA  1 
ATOM   3855 C C   . LEU B 2 266 ? 77.758  95.666  147.642 1.00 71.73  ?  260 LEU B C   1 
ATOM   3856 O O   . LEU B 2 266 ? 77.755  96.051  148.816 1.00 71.73  ?  260 LEU B O   1 
ATOM   3857 C CB  . LEU B 2 266 ? 77.507  97.549  146.022 1.00 71.73  ?  260 LEU B CB  1 
ATOM   3858 C CG  . LEU B 2 266 ? 78.014  98.347  144.819 1.00 71.73  ?  260 LEU B CG  1 
ATOM   3859 C CD1 . LEU B 2 266 ? 77.033  99.454  144.464 1.00 71.73  ?  260 LEU B CD1 1 
ATOM   3860 C CD2 . LEU B 2 266 ? 79.399  98.916  145.086 1.00 71.73  ?  260 LEU B CD2 1 
ATOM   3861 N N   . ARG B 2 267 ? 77.160  94.536  147.259 1.00 77.86  ?  261 ARG B N   1 
ATOM   3862 C CA  . ARG B 2 267 ? 76.473  93.692  148.229 1.00 77.86  ?  261 ARG B CA  1 
ATOM   3863 C C   . ARG B 2 267 ? 77.460  92.858  149.036 1.00 77.86  ?  261 ARG B C   1 
ATOM   3864 O O   . ARG B 2 267 ? 77.330  92.750  150.260 1.00 77.86  ?  261 ARG B O   1 
ATOM   3865 C CB  . ARG B 2 267 ? 75.467  92.788  147.514 1.00 77.86  ?  261 ARG B CB  1 
ATOM   3866 C CG  . ARG B 2 267 ? 74.448  93.544  146.674 1.00 77.86  ?  261 ARG B CG  1 
ATOM   3867 C CD  . ARG B 2 267 ? 73.587  92.599  145.853 1.00 77.86  ?  261 ARG B CD  1 
ATOM   3868 N NE  . ARG B 2 267 ? 72.792  91.706  146.691 1.00 77.86  ?  261 ARG B NE  1 
ATOM   3869 C CZ  . ARG B 2 267 ? 71.939  90.801  146.222 1.00 77.86  ?  261 ARG B CZ  1 
ATOM   3870 N NH1 . ARG B 2 267 ? 71.258  90.034  147.062 1.00 77.86  1  261 ARG B NH1 1 
ATOM   3871 N NH2 . ARG B 2 267 ? 71.763  90.660  144.915 1.00 77.86  ?  261 ARG B NH2 1 
ATOM   3872 N N   . ALA B 2 268 ? 78.450  92.262  148.369 1.00 79.57  ?  262 ALA B N   1 
ATOM   3873 C CA  . ALA B 2 268 ? 79.480  91.503  149.066 1.00 79.57  ?  262 ALA B CA  1 
ATOM   3874 C C   . ALA B 2 268 ? 80.590  92.392  149.610 1.00 79.57  ?  262 ALA B C   1 
ATOM   3875 O O   . ALA B 2 268 ? 81.252  92.010  150.580 1.00 79.57  ?  262 ALA B O   1 
ATOM   3876 C CB  . ALA B 2 268 ? 80.080  90.449  148.133 1.00 79.57  ?  262 ALA B CB  1 
ATOM   3877 N N   . ASP B 2 269 ? 80.806  93.562  149.009 1.00 80.95  ?  263 ASP B N   1 
ATOM   3878 C CA  . ASP B 2 269 ? 81.810  94.515  149.480 1.00 80.95  ?  263 ASP B CA  1 
ATOM   3879 C C   . ASP B 2 269 ? 83.212  93.910  149.410 1.00 80.95  ?  263 ASP B C   1 
ATOM   3880 O O   . ASP B 2 269 ? 83.958  93.895  150.392 1.00 80.95  ?  263 ASP B O   1 
ATOM   3881 C CB  . ASP B 2 269 ? 81.486  94.988  150.899 1.00 80.95  ?  263 ASP B CB  1 
ATOM   3882 C CG  . ASP B 2 269 ? 82.277  96.219  151.302 1.00 80.95  ?  263 ASP B CG  1 
ATOM   3883 O OD1 . ASP B 2 269 ? 83.377  96.434  150.750 1.00 80.95  ?  263 ASP B OD1 1 
ATOM   3884 O OD2 . ASP B 2 269 ? 81.797  96.975  152.173 1.00 80.95  ?  263 ASP B OD2 1 
ATOM   3885 N N   . GLN B 2 270 ? 83.569  93.409  148.231 1.00 79.96  ?  264 GLN B N   1 
ATOM   3886 C CA  . GLN B 2 270 ? 84.894  92.843  148.007 1.00 79.96  ?  264 GLN B CA  1 
ATOM   3887 C C   . GLN B 2 270 ? 85.040  92.534  146.523 1.00 79.96  ?  264 GLN B C   1 
ATOM   3888 O O   . GLN B 2 270 ? 84.079  92.612  145.753 1.00 79.96  ?  264 GLN B O   1 
ATOM   3889 C CB  . GLN B 2 270 ? 85.122  91.585  148.850 1.00 79.96  ?  264 GLN B CB  1 
ATOM   3890 C CG  . GLN B 2 270 ? 84.217  90.417  148.495 1.00 79.96  ?  264 GLN B CG  1 
ATOM   3891 C CD  . GLN B 2 270 ? 84.430  89.223  149.404 1.00 79.96  ?  264 GLN B CD  1 
ATOM   3892 O OE1 . GLN B 2 270 ? 84.758  88.129  148.945 1.00 79.96  ?  264 GLN B OE1 1 
ATOM   3893 N NE2 . GLN B 2 270 ? 84.243  89.427  150.703 1.00 79.96  ?  264 GLN B NE2 1 
ATOM   3894 N N   . GLU B 2 271 ? 86.263  92.181  146.135 1.00 73.96  ?  265 GLU B N   1 
ATOM   3895 C CA  . GLU B 2 271 ? 86.543  91.838  144.749 1.00 73.96  ?  265 GLU B CA  1 
ATOM   3896 C C   . GLU B 2 271 ? 86.010  90.448  144.425 1.00 73.96  ?  265 GLU B C   1 
ATOM   3897 O O   . GLU B 2 271 ? 86.151  89.510  145.215 1.00 73.96  ?  265 GLU B O   1 
ATOM   3898 C CB  . GLU B 2 271 ? 88.048  91.907  144.485 1.00 73.96  ?  265 GLU B CB  1 
ATOM   3899 C CG  . GLU B 2 271 ? 88.487  91.331  143.143 1.00 73.96  ?  265 GLU B CG  1 
ATOM   3900 C CD  . GLU B 2 271 ? 88.830  89.852  143.214 1.00 73.96  ?  265 GLU B CD  1 
ATOM   3901 O OE1 . GLU B 2 271 ? 88.643  89.241  144.288 1.00 73.96  ?  265 GLU B OE1 1 
ATOM   3902 O OE2 . GLU B 2 271 ? 89.292  89.300  142.194 1.00 73.96  ?  265 GLU B OE2 1 
ATOM   3903 N N   . LEU B 2 272 ? 85.391  90.321  143.253 1.00 74.18  ?  266 LEU B N   1 
ATOM   3904 C CA  . LEU B 2 272 ? 84.849  89.050  142.785 1.00 74.18  ?  266 LEU B CA  1 
ATOM   3905 C C   . LEU B 2 272 ? 85.809  88.297  141.876 1.00 74.18  ?  266 LEU B C   1 
ATOM   3906 O O   . LEU B 2 272 ? 86.024  87.097  142.070 1.00 74.18  ?  266 LEU B O   1 
ATOM   3907 C CB  . LEU B 2 272 ? 83.529  89.281  142.042 1.00 74.18  ?  266 LEU B CB  1 
ATOM   3908 C CG  . LEU B 2 272 ? 82.409  89.965  142.828 1.00 74.18  ?  266 LEU B CG  1 
ATOM   3909 C CD1 . LEU B 2 272 ? 81.165  90.093  141.962 1.00 74.18  ?  266 LEU B CD1 1 
ATOM   3910 C CD2 . LEU B 2 272 ? 82.096  89.209  144.110 1.00 74.18  ?  266 LEU B CD2 1 
ATOM   3911 N N   . MET B 2 273 ? 86.390  88.972  140.887 1.00 73.12  ?  267 MET B N   1 
ATOM   3912 C CA  . MET B 2 273 ? 87.322  88.339  139.967 1.00 73.12  ?  267 MET B CA  1 
ATOM   3913 C C   . MET B 2 273 ? 88.311  89.383  139.473 1.00 73.12  ?  267 MET B C   1 
ATOM   3914 O O   . MET B 2 273 ? 87.958  90.549  139.274 1.00 73.12  ?  267 MET B O   1 
ATOM   3915 C CB  . MET B 2 273 ? 86.591  87.693  138.782 1.00 73.12  ?  267 MET B CB  1 
ATOM   3916 C CG  . MET B 2 273 ? 87.507  86.998  137.785 1.00 73.12  ?  267 MET B CG  1 
ATOM   3917 S SD  . MET B 2 273 ? 88.492  85.684  138.531 1.00 73.12  ?  267 MET B SD  1 
ATOM   3918 C CE  . MET B 2 273 ? 89.436  85.123  137.116 1.00 73.12  ?  267 MET B CE  1 
ATOM   3919 N N   . THR B 2 274 ? 89.554  88.950  139.276 1.00 69.39  ?  268 THR B N   1 
ATOM   3920 C CA  . THR B 2 274 ? 90.638  89.815  138.823 1.00 69.39  ?  268 THR B CA  1 
ATOM   3921 C C   . THR B 2 274 ? 91.003  89.415  137.398 1.00 69.39  ?  268 THR B C   1 
ATOM   3922 O O   . THR B 2 274 ? 91.570  88.340  137.175 1.00 69.39  ?  268 THR B O   1 
ATOM   3923 C CB  . THR B 2 274 ? 91.848  89.708  139.749 1.00 69.39  ?  268 THR B CB  1 
ATOM   3924 O OG1 . THR B 2 274 ? 91.461  90.043  141.088 1.00 69.39  ?  268 THR B OG1 1 
ATOM   3925 C CG2 . THR B 2 274 ? 92.958  90.648  139.295 1.00 69.39  ?  268 THR B CG2 1 
ATOM   3926 N N   . TYR B 2 275 ? 90.678  90.279  136.440 1.00 68.15  ?  269 TYR B N   1 
ATOM   3927 C CA  . TYR B 2 275 ? 90.966  90.031  135.032 1.00 68.15  ?  269 TYR B CA  1 
ATOM   3928 C C   . TYR B 2 275 ? 92.400  90.465  134.751 1.00 68.15  ?  269 TYR B C   1 
ATOM   3929 O O   . TYR B 2 275 ? 92.704  91.663  134.742 1.00 68.15  ?  269 TYR B O   1 
ATOM   3930 C CB  . TYR B 2 275 ? 89.979  90.779  134.140 1.00 68.15  ?  269 TYR B CB  1 
ATOM   3931 C CG  . TYR B 2 275 ? 88.537  90.635  134.572 1.00 68.15  ?  269 TYR B CG  1 
ATOM   3932 C CD1 . TYR B 2 275 ? 87.772  89.552  134.160 1.00 68.15  ?  269 TYR B CD1 1 
ATOM   3933 C CD2 . TYR B 2 275 ? 87.941  91.584  135.392 1.00 68.15  ?  269 TYR B CD2 1 
ATOM   3934 C CE1 . TYR B 2 275 ? 86.454  89.418  134.554 1.00 68.15  ?  269 TYR B CE1 1 
ATOM   3935 C CE2 . TYR B 2 275 ? 86.624  91.458  135.791 1.00 68.15  ?  269 TYR B CE2 1 
ATOM   3936 C CZ  . TYR B 2 275 ? 85.886  90.374  135.369 1.00 68.15  ?  269 TYR B CZ  1 
ATOM   3937 O OH  . TYR B 2 275 ? 84.574  90.245  135.765 1.00 68.15  ?  269 TYR B OH  1 
ATOM   3938 N N   . SER B 2 276 ? 93.281  89.494  134.523 1.00 67.67  ?  270 SER B N   1 
ATOM   3939 C CA  . SER B 2 276 ? 94.689  89.780  134.295 1.00 67.67  ?  270 SER B CA  1 
ATOM   3940 C C   . SER B 2 276 ? 95.287  88.686  133.424 1.00 67.67  ?  270 SER B C   1 
ATOM   3941 O O   . SER B 2 276 ? 94.770  87.568  133.353 1.00 67.67  ?  270 SER B O   1 
ATOM   3942 C CB  . SER B 2 276 ? 95.460  89.891  135.616 1.00 67.67  ?  270 SER B CB  1 
ATOM   3943 O OG  . SER B 2 276 ? 95.389  88.681  136.350 1.00 67.67  ?  270 SER B OG  1 
ATOM   3944 N N   . HIS B 2 277 ? 96.389  89.026  132.759 1.00 69.18  ?  271 HIS B N   1 
ATOM   3945 C CA  . HIS B 2 277 ? 97.095  88.083  131.904 1.00 69.18  ?  271 HIS B CA  1 
ATOM   3946 C C   . HIS B 2 277 ? 98.578  88.422  131.921 1.00 69.18  ?  271 HIS B C   1 
ATOM   3947 O O   . HIS B 2 277 ? 98.962  89.585  132.067 1.00 69.18  ?  271 HIS B O   1 
ATOM   3948 C CB  . HIS B 2 277 ? 96.554  88.111  130.470 1.00 69.18  ?  271 HIS B CB  1 
ATOM   3949 C CG  . HIS B 2 277 ? 97.113  87.035  129.593 1.00 69.18  ?  271 HIS B CG  1 
ATOM   3950 N ND1 . HIS B 2 277 ? 97.147  85.710  129.972 1.00 69.18  ?  271 HIS B ND1 1 
ATOM   3951 C CD2 . HIS B 2 277 ? 97.657  87.086  128.355 1.00 69.18  ?  271 HIS B CD2 1 
ATOM   3952 C CE1 . HIS B 2 277 ? 97.690  84.992  129.005 1.00 69.18  ?  271 HIS B CE1 1 
ATOM   3953 N NE2 . HIS B 2 277 ? 98.009  85.803  128.012 1.00 69.18  ?  271 HIS B NE2 1 
ATOM   3954 N N   . ASP B 2 278 ? 99.409  87.388  131.769 1.00 69.70  ?  272 ASP B N   1 
ATOM   3955 C CA  . ASP B 2 278 ? 100.853 87.586  131.840 1.00 69.70  ?  272 ASP B CA  1 
ATOM   3956 C C   . ASP B 2 278 ? 101.379 88.366  130.642 1.00 69.70  ?  272 ASP B C   1 
ATOM   3957 O O   . ASP B 2 278 ? 102.292 89.186  130.794 1.00 69.70  ?  272 ASP B O   1 
ATOM   3958 C CB  . ASP B 2 278 ? 101.560 86.234  131.940 1.00 69.70  ?  272 ASP B CB  1 
ATOM   3959 C CG  . ASP B 2 278 ? 101.148 85.450  133.170 1.00 69.70  ?  272 ASP B CG  1 
ATOM   3960 O OD1 . ASP B 2 278 ? 100.314 85.958  133.949 1.00 69.70  ?  272 ASP B OD1 1 
ATOM   3961 O OD2 . ASP B 2 278 ? 101.656 84.325  133.357 1.00 69.70  ?  272 ASP B OD2 1 
ATOM   3962 N N   . ASN B 2 279 ? 100.825 88.130  129.452 1.00 69.73  ?  273 ASN B N   1 
ATOM   3963 C CA  . ASN B 2 279 ? 101.307 88.806  128.253 1.00 69.73  ?  273 ASN B CA  1 
ATOM   3964 C C   . ASN B 2 279 ? 100.911 90.275  128.200 1.00 69.73  ?  273 ASN B C   1 
ATOM   3965 O O   . ASN B 2 279 ? 101.379 90.990  127.306 1.00 69.73  ?  273 ASN B O   1 
ATOM   3966 C CB  . ASN B 2 279 ? 100.784 88.093  127.005 1.00 69.73  ?  273 ASN B CB  1 
ATOM   3967 C CG  . ASN B 2 279 ? 101.183 86.632  126.957 1.00 69.73  ?  273 ASN B CG  1 
ATOM   3968 O OD1 . ASN B 2 279 ? 100.331 85.744  126.924 1.00 69.73  ?  273 ASN B OD1 1 
ATOM   3969 N ND2 . ASN B 2 279 ? 102.486 86.375  126.953 1.00 69.73  ?  273 ASN B ND2 1 
ATOM   3970 N N   . ILE B 2 280 ? 100.073 90.741  129.119 1.00 67.46  ?  274 ILE B N   1 
ATOM   3971 C CA  . ILE B 2 280 ? 99.620  92.127  129.149 1.00 67.46  ?  274 ILE B CA  1 
ATOM   3972 C C   . ILE B 2 280 ? 100.387 92.836  130.258 1.00 67.46  ?  274 ILE B C   1 
ATOM   3973 O O   . ILE B 2 280 ? 100.182 92.560  131.444 1.00 67.46  ?  274 ILE B O   1 
ATOM   3974 C CB  . ILE B 2 280 ? 98.104  92.223  129.367 1.00 67.46  ?  274 ILE B CB  1 
ATOM   3975 C CG1 . ILE B 2 280 ? 97.364  91.344  128.354 1.00 67.46  ?  274 ILE B CG1 1 
ATOM   3976 C CG2 . ILE B 2 280 ? 97.640  93.668  129.242 1.00 67.46  ?  274 ILE B CG2 1 
ATOM   3977 C CD1 . ILE B 2 280 ? 95.857  91.363  128.509 1.00 67.46  ?  274 ILE B CD1 1 
ATOM   3978 N N   . ILE B 2 281 ? 101.271 93.753  129.872 1.00 68.20  ?  275 ILE B N   1 
ATOM   3979 C CA  . ILE B 2 281 ? 102.070 94.515  130.826 1.00 68.20  ?  275 ILE B CA  1 
ATOM   3980 C C   . ILE B 2 281 ? 101.765 96.004  130.796 1.00 68.20  ?  275 ILE B C   1 
ATOM   3981 O O   . ILE B 2 281 ? 102.195 96.724  131.711 1.00 68.20  ?  275 ILE B O   1 
ATOM   3982 C CB  . ILE B 2 281 ? 103.581 94.287  130.600 1.00 68.20  ?  275 ILE B CB  1 
ATOM   3983 C CG1 . ILE B 2 281 ? 103.972 94.666  129.169 1.00 68.20  ?  275 ILE B CG1 1 
ATOM   3984 C CG2 . ILE B 2 281 ? 103.945 92.839  130.890 1.00 68.20  ?  275 ILE B CG2 1 
ATOM   3985 C CD1 . ILE B 2 281 ? 105.455 94.541  128.884 1.00 68.20  ?  275 ILE B CD1 1 
ATOM   3986 N N   . CYS B 2 282 ? 101.046 96.494  129.791 1.00 66.75  ?  276 CYS B N   1 
ATOM   3987 C CA  . CYS B 2 282 ? 100.743 97.913  129.675 1.00 66.75  ?  276 CYS B CA  1 
ATOM   3988 C C   . CYS B 2 282 ? 99.505  98.258  130.491 1.00 66.75  ?  276 CYS B C   1 
ATOM   3989 O O   . CYS B 2 282 ? 98.539  97.490  130.536 1.00 66.75  ?  276 CYS B O   1 
ATOM   3990 C CB  . CYS B 2 282 ? 100.531 98.296  128.210 1.00 66.75  ?  276 CYS B CB  1 
ATOM   3991 S SG  . CYS B 2 282 ? 101.963 97.981  127.153 1.00 66.75  ?  276 CYS B SG  1 
ATOM   3992 N N   . GLY B 2 283 ? 99.539  99.421  131.131 1.00 64.82  ?  277 GLY B N   1 
ATOM   3993 C CA  . GLY B 2 283 ? 98.447  99.841  131.988 1.00 64.82  ?  277 GLY B CA  1 
ATOM   3994 C C   . GLY B 2 283 ? 97.135  99.965  131.236 1.00 64.82  ?  277 GLY B C   1 
ATOM   3995 O O   . GLY B 2 283 ? 97.057  99.892  130.010 1.00 64.82  ?  277 GLY B O   1 
ATOM   3996 N N   . ILE B 2 284 ? 96.073  100.162 132.014 1.00 63.83  ?  278 ILE B N   1 
ATOM   3997 C CA  . ILE B 2 284 ? 94.718  100.290 131.491 1.00 63.83  ?  278 ILE B CA  1 
ATOM   3998 C C   . ILE B 2 284 ? 94.308  101.753 131.562 1.00 63.83  ?  278 ILE B C   1 
ATOM   3999 O O   . ILE B 2 284 ? 94.744  102.500 132.446 1.00 63.83  ?  278 ILE B O   1 
ATOM   4000 C CB  . ILE B 2 284 ? 93.724  99.402  132.268 1.00 63.83  ?  278 ILE B CB  1 
ATOM   4001 C CG1 . ILE B 2 284 ? 94.336  98.020  132.513 1.00 63.83  ?  278 ILE B CG1 1 
ATOM   4002 C CG2 . ILE B 2 284 ? 92.408  99.281  131.506 1.00 63.83  ?  278 ILE B CG2 1 
ATOM   4003 C CD1 . ILE B 2 284 ? 93.386  97.022  133.131 1.00 63.83  ?  278 ILE B CD1 1 
ATOM   4004 N N   . THR B 2 285 ? 93.458  102.162 130.620 1.00 62.11  ?  279 THR B N   1 
ATOM   4005 C CA  . THR B 2 285 ? 92.996  103.543 130.543 1.00 62.11  ?  279 THR B CA  1 
ATOM   4006 C C   . THR B 2 285 ? 91.484  103.698 130.609 1.00 62.11  ?  279 THR B C   1 
ATOM   4007 O O   . THR B 2 285 ? 91.016  104.791 130.953 1.00 62.11  ?  279 THR B O   1 
ATOM   4008 C CB  . THR B 2 285 ? 93.492  104.201 129.247 1.00 62.11  ?  279 THR B CB  1 
ATOM   4009 O OG1 . THR B 2 285 ? 94.856  103.829 129.011 1.00 62.11  ?  279 THR B OG1 1 
ATOM   4010 C CG2 . THR B 2 285 ? 93.396  105.718 129.346 1.00 62.11  ?  279 THR B CG2 1 
ATOM   4011 N N   . SER B 2 286 ? 90.707  102.661 130.303 1.00 61.83  ?  280 SER B N   1 
ATOM   4012 C CA  . SER B 2 286 ? 89.257  102.771 130.297 1.00 61.83  ?  280 SER B CA  1 
ATOM   4013 C C   . SER B 2 286 ? 88.645  101.409 130.586 1.00 61.83  ?  280 SER B C   1 
ATOM   4014 O O   . SER B 2 286 ? 89.267  100.369 130.350 1.00 61.83  ?  280 SER B O   1 
ATOM   4015 C CB  . SER B 2 286 ? 88.743  103.308 128.957 1.00 61.83  ?  280 SER B CB  1 
ATOM   4016 O OG  . SER B 2 286 ? 87.328  103.366 128.939 1.00 61.83  ?  280 SER B OG  1 
ATOM   4017 N N   . VAL B 2 287 ? 87.422  101.429 131.109 1.00 63.03  ?  281 VAL B N   1 
ATOM   4018 C CA  . VAL B 2 287 ? 86.667  100.213 131.397 1.00 63.03  ?  281 VAL B CA  1 
ATOM   4019 C C   . VAL B 2 287 ? 85.204  100.482 131.077 1.00 63.03  ?  281 VAL B C   1 
ATOM   4020 O O   . VAL B 2 287 ? 84.692  101.577 131.330 1.00 63.03  ?  281 VAL B O   1 
ATOM   4021 C CB  . VAL B 2 287 ? 86.840  99.766  132.865 1.00 63.03  ?  281 VAL B CB  1 
ATOM   4022 C CG1 . VAL B 2 287 ? 86.007  98.523  133.146 1.00 63.03  ?  281 VAL B CG1 1 
ATOM   4023 C CG2 . VAL B 2 287 ? 88.306  99.508  133.182 1.00 63.03  ?  281 VAL B CG2 1 
ATOM   4024 N N   . SER B 2 288 ? 84.530  99.480  130.516 1.00 63.73  ?  282 SER B N   1 
ATOM   4025 C CA  . SER B 2 288 ? 83.130  99.629  130.147 1.00 63.73  ?  282 SER B CA  1 
ATOM   4026 C C   . SER B 2 288 ? 82.488  98.254  130.049 1.00 63.73  ?  282 SER B C   1 
ATOM   4027 O O   . SER B 2 288 ? 83.160  97.257  129.772 1.00 63.73  ?  282 SER B O   1 
ATOM   4028 C CB  . SER B 2 288 ? 82.979  100.382 128.820 1.00 63.73  ?  282 SER B CB  1 
ATOM   4029 O OG  . SER B 2 288 ? 81.614  100.606 128.513 1.00 63.73  ?  282 SER B OG  1 
ATOM   4030 N N   . PHE B 2 289 ? 81.178  98.218  130.279 1.00 65.34  ?  283 PHE B N   1 
ATOM   4031 C CA  . PHE B 2 289 ? 80.378  97.007  130.183 1.00 65.34  ?  283 PHE B CA  1 
ATOM   4032 C C   . PHE B 2 289 ? 79.369  97.141  129.050 1.00 65.34  ?  283 PHE B C   1 
ATOM   4033 O O   . PHE B 2 289 ? 79.112  98.233  128.537 1.00 65.34  ?  283 PHE B O   1 
ATOM   4034 C CB  . PHE B 2 289 ? 79.645  96.719  131.501 1.00 65.34  ?  283 PHE B CB  1 
ATOM   4035 C CG  . PHE B 2 289 ? 80.521  96.138  132.571 1.00 65.34  ?  283 PHE B CG  1 
ATOM   4036 C CD1 . PHE B 2 289 ? 80.725  94.770  132.648 1.00 65.34  ?  283 PHE B CD1 1 
ATOM   4037 C CD2 . PHE B 2 289 ? 81.133  96.955  133.506 1.00 65.34  ?  283 PHE B CD2 1 
ATOM   4038 C CE1 . PHE B 2 289 ? 81.526  94.229  133.633 1.00 65.34  ?  283 PHE B CE1 1 
ATOM   4039 C CE2 . PHE B 2 289 ? 81.936  96.420  134.493 1.00 65.34  ?  283 PHE B CE2 1 
ATOM   4040 C CZ  . PHE B 2 289 ? 82.132  95.055  134.557 1.00 65.34  ?  283 PHE B CZ  1 
ATOM   4041 N N   . SER B 2 290 ? 78.793  96.006  128.665 1.00 66.13  ?  284 SER B N   1 
ATOM   4042 C CA  . SER B 2 290 ? 77.735  95.975  127.671 1.00 66.13  ?  284 SER B CA  1 
ATOM   4043 C C   . SER B 2 290 ? 76.382  96.170  128.353 1.00 66.13  ?  284 SER B C   1 
ATOM   4044 O O   . SER B 2 290 ? 76.287  96.321  129.573 1.00 66.13  ?  284 SER B O   1 
ATOM   4045 C CB  . SER B 2 290 ? 77.778  94.662  126.890 1.00 66.13  ?  284 SER B CB  1 
ATOM   4046 O OG  . SER B 2 290 ? 77.591  93.551  127.749 1.00 66.13  ?  284 SER B OG  1 
ATOM   4047 N N   . LYS B 2 291 ? 75.314  96.168  127.552 1.00 66.19  ?  285 LYS B N   1 
ATOM   4048 C CA  . LYS B 2 291 ? 73.979  96.338  128.115 1.00 66.19  ?  285 LYS B CA  1 
ATOM   4049 C C   . LYS B 2 291 ? 73.618  95.192  129.051 1.00 66.19  ?  285 LYS B C   1 
ATOM   4050 O O   . LYS B 2 291 ? 72.810  95.372  129.970 1.00 66.19  ?  285 LYS B O   1 
ATOM   4051 C CB  . LYS B 2 291 ? 72.946  96.452  126.993 1.00 66.19  ?  285 LYS B CB  1 
ATOM   4052 C CG  . LYS B 2 291 ? 71.551  96.817  127.474 1.00 66.19  ?  285 LYS B CG  1 
ATOM   4053 C CD  . LYS B 2 291 ? 70.588  96.991  126.311 1.00 66.19  ?  285 LYS B CD  1 
ATOM   4054 C CE  . LYS B 2 291 ? 69.207  97.413  126.786 1.00 66.19  ?  285 LYS B CE  1 
ATOM   4055 N NZ  . LYS B 2 291 ? 69.226  98.733  127.475 1.00 66.19  1  285 LYS B NZ  1 
ATOM   4056 N N   . SER B 2 292 ? 74.202  94.012  128.839 1.00 68.86  ?  286 SER B N   1 
ATOM   4057 C CA  . SER B 2 292 ? 73.941  92.859  129.691 1.00 68.86  ?  286 SER B CA  1 
ATOM   4058 C C   . SER B 2 292 ? 74.982  92.710  130.794 1.00 68.86  ?  286 SER B C   1 
ATOM   4059 O O   . SER B 2 292 ? 74.647  92.287  131.906 1.00 68.86  ?  286 SER B O   1 
ATOM   4060 C CB  . SER B 2 292 ? 73.896  91.582  128.847 1.00 68.86  ?  286 SER B CB  1 
ATOM   4061 O OG  . SER B 2 292 ? 75.103  91.404  128.127 1.00 68.86  ?  286 SER B OG  1 
ATOM   4062 N N   . GLY B 2 293 ? 76.238  93.050  130.510 1.00 68.03  ?  287 GLY B N   1 
ATOM   4063 C CA  . GLY B 2 293 ? 77.312  92.969  131.480 1.00 68.03  ?  287 GLY B CA  1 
ATOM   4064 C C   . GLY B 2 293 ? 78.262  91.811  131.271 1.00 68.03  ?  287 GLY B C   1 
ATOM   4065 O O   . GLY B 2 293 ? 79.301  91.759  131.943 1.00 68.03  ?  287 GLY B O   1 
ATOM   4066 N N   . ARG B 2 294 ? 77.948  90.881  130.367 1.00 70.54  ?  288 ARG B N   1 
ATOM   4067 C CA  . ARG B 2 294 ? 78.839  89.750  130.133 1.00 70.54  ?  288 ARG B CA  1 
ATOM   4068 C C   . ARG B 2 294 ? 80.184  90.209  129.586 1.00 70.54  ?  288 ARG B C   1 
ATOM   4069 O O   . ARG B 2 294 ? 81.237  89.714  130.007 1.00 70.54  ?  288 ARG B O   1 
ATOM   4070 C CB  . ARG B 2 294 ? 78.186  88.757  129.171 1.00 70.54  ?  288 ARG B CB  1 
ATOM   4071 C CG  . ARG B 2 294 ? 77.043  87.953  129.774 1.00 70.54  ?  288 ARG B CG  1 
ATOM   4072 C CD  . ARG B 2 294 ? 77.538  86.949  130.808 1.00 70.54  ?  288 ARG B CD  1 
ATOM   4073 N NE  . ARG B 2 294 ? 78.512  86.015  130.249 1.00 70.54  ?  288 ARG B NE  1 
ATOM   4074 C CZ  . ARG B 2 294 ? 78.199  84.907  129.583 1.00 70.54  ?  288 ARG B CZ  1 
ATOM   4075 N NH1 . ARG B 2 294 ? 76.929  84.580  129.378 1.00 70.54  1  288 ARG B NH1 1 
ATOM   4076 N NH2 . ARG B 2 294 ? 79.161  84.123  129.115 1.00 70.54  ?  288 ARG B NH2 1 
ATOM   4077 N N   . LEU B 2 295 ? 80.172  91.153  128.648 1.00 66.91  ?  289 LEU B N   1 
ATOM   4078 C CA  . LEU B 2 295 ? 81.381  91.611  127.972 1.00 66.91  ?  289 LEU B CA  1 
ATOM   4079 C C   . LEU B 2 295 ? 81.918  92.843  128.692 1.00 66.91  ?  289 LEU B C   1 
ATOM   4080 O O   . LEU B 2 295 ? 81.304  93.914  128.646 1.00 66.91  ?  289 LEU B O   1 
ATOM   4081 C CB  . LEU B 2 295 ? 81.094  91.916  126.504 1.00 66.91  ?  289 LEU B CB  1 
ATOM   4082 C CG  . LEU B 2 295 ? 80.556  90.750  125.671 1.00 66.91  ?  289 LEU B CG  1 
ATOM   4083 C CD1 . LEU B 2 295 ? 80.274  91.199  124.246 1.00 66.91  ?  289 LEU B CD1 1 
ATOM   4084 C CD2 . LEU B 2 295 ? 81.526  89.579  125.682 1.00 66.91  ?  289 LEU B CD2 1 
ATOM   4085 N N   . LEU B 2 296 ? 83.062  92.687  129.353 1.00 65.00  ?  290 LEU B N   1 
ATOM   4086 C CA  . LEU B 2 296 ? 83.761  93.789  130.000 1.00 65.00  ?  290 LEU B CA  1 
ATOM   4087 C C   . LEU B 2 296 ? 84.858  94.273  129.059 1.00 65.00  ?  290 LEU B C   1 
ATOM   4088 O O   . LEU B 2 296 ? 85.791  93.523  128.751 1.00 65.00  ?  290 LEU B O   1 
ATOM   4089 C CB  . LEU B 2 296 ? 84.348  93.350  131.342 1.00 65.00  ?  290 LEU B CB  1 
ATOM   4090 C CG  . LEU B 2 296 ? 84.779  94.450  132.318 1.00 65.00  ?  290 LEU B CG  1 
ATOM   4091 C CD1 . LEU B 2 296 ? 85.133  93.843  133.667 1.00 65.00  ?  290 LEU B CD1 1 
ATOM   4092 C CD2 . LEU B 2 296 ? 85.951  95.258  131.779 1.00 65.00  ?  290 LEU B CD2 1 
ATOM   4093 N N   . LEU B 2 297 ? 84.738  95.515  128.600 1.00 63.07  ?  291 LEU B N   1 
ATOM   4094 C CA  . LEU B 2 297 ? 85.662  96.093  127.634 1.00 63.07  ?  291 LEU B CA  1 
ATOM   4095 C C   . LEU B 2 297 ? 86.612  97.047  128.345 1.00 63.07  ?  291 LEU B C   1 
ATOM   4096 O O   . LEU B 2 297 ? 86.178  97.869  129.159 1.00 63.07  ?  291 LEU B O   1 
ATOM   4097 C CB  . LEU B 2 297 ? 84.903  96.830  126.528 1.00 63.07  ?  291 LEU B CB  1 
ATOM   4098 C CG  . LEU B 2 297 ? 83.981  95.980  125.646 1.00 63.07  ?  291 LEU B CG  1 
ATOM   4099 C CD1 . LEU B 2 297 ? 82.750  95.505  126.408 1.00 63.07  ?  291 LEU B CD1 1 
ATOM   4100 C CD2 . LEU B 2 297 ? 83.570  96.754  124.406 1.00 63.07  ?  291 LEU B CD2 1 
ATOM   4101 N N   . ALA B 2 298 ? 87.904  96.937  128.036 1.00 63.03  ?  292 ALA B N   1 
ATOM   4102 C CA  . ALA B 2 298 ? 88.915  97.784  128.658 1.00 63.03  ?  292 ALA B CA  1 
ATOM   4103 C C   . ALA B 2 298 ? 90.039  98.061  127.673 1.00 63.03  ?  292 ALA B C   1 
ATOM   4104 O O   . ALA B 2 298 ? 90.561  97.134  127.047 1.00 63.03  ?  292 ALA B O   1 
ATOM   4105 C CB  . ALA B 2 298 ? 89.477  97.133  129.926 1.00 63.03  ?  292 ALA B CB  1 
ATOM   4106 N N   . GLY B 2 299 ? 90.410  99.333  127.542 1.00 62.87  ?  293 GLY B N   1 
ATOM   4107 C CA  . GLY B 2 299 ? 91.504  99.721  126.670 1.00 62.87  ?  293 GLY B CA  1 
ATOM   4108 C C   . GLY B 2 299 ? 92.817  99.720  127.426 1.00 62.87  ?  293 GLY B C   1 
ATOM   4109 O O   . GLY B 2 299 ? 92.888  100.191 128.565 1.00 62.87  ?  293 GLY B O   1 
ATOM   4110 N N   . TYR B 2 300 ? 93.857  99.182  126.792 1.00 63.33  ?  294 TYR B N   1 
ATOM   4111 C CA  . TYR B 2 300 ? 95.171  99.063  127.404 1.00 63.33  ?  294 TYR B CA  1 
ATOM   4112 C C   . TYR B 2 300 ? 96.162  99.961  126.678 1.00 63.33  ?  294 TYR B C   1 
ATOM   4113 O O   . TYR B 2 300 ? 95.942  100.354 125.528 1.00 63.33  ?  294 TYR B O   1 
ATOM   4114 C CB  . TYR B 2 300 ? 95.662  97.610  127.375 1.00 63.33  ?  294 TYR B CB  1 
ATOM   4115 C CG  . TYR B 2 300 ? 94.831  96.674  128.223 1.00 63.33  ?  294 TYR B CG  1 
ATOM   4116 C CD1 . TYR B 2 300 ? 93.560  96.286  127.821 1.00 63.33  ?  294 TYR B CD1 1 
ATOM   4117 C CD2 . TYR B 2 300 ? 95.319  96.176  129.423 1.00 63.33  ?  294 TYR B CD2 1 
ATOM   4118 C CE1 . TYR B 2 300 ? 92.797  95.431  128.592 1.00 63.33  ?  294 TYR B CE1 1 
ATOM   4119 C CE2 . TYR B 2 300 ? 94.563  95.320  130.200 1.00 63.33  ?  294 TYR B CE2 1 
ATOM   4120 C CZ  . TYR B 2 300 ? 93.304  94.951  129.780 1.00 63.33  ?  294 TYR B CZ  1 
ATOM   4121 O OH  . TYR B 2 300 ? 92.548  94.098  130.552 1.00 63.33  ?  294 TYR B OH  1 
ATOM   4122 N N   . ASP B 2 301 ? 97.260  100.279 127.359 1.00 65.06  ?  295 ASP B N   1 
ATOM   4123 C CA  . ASP B 2 301 ? 98.298  101.133 126.786 1.00 65.06  ?  295 ASP B CA  1 
ATOM   4124 C C   . ASP B 2 301 ? 99.132  100.423 125.726 1.00 65.06  ?  295 ASP B C   1 
ATOM   4125 O O   . ASP B 2 301 ? 100.124 101.003 125.262 1.00 65.06  ?  295 ASP B O   1 
ATOM   4126 C CB  . ASP B 2 301 ? 99.208  101.659 127.897 1.00 65.06  ?  295 ASP B CB  1 
ATOM   4127 N N   . ASP B 2 302 ? 98.773  99.202  125.329 1.00 66.15  ?  296 ASP B N   1 
ATOM   4128 C CA  . ASP B 2 302 ? 99.452  98.488  124.258 1.00 66.15  ?  296 ASP B CA  1 
ATOM   4129 C C   . ASP B 2 302 ? 98.870  98.814  122.886 1.00 66.15  ?  296 ASP B C   1 
ATOM   4130 O O   . ASP B 2 302 ? 99.012  98.014  121.954 1.00 66.15  ?  296 ASP B O   1 
ATOM   4131 C CB  . ASP B 2 302 ? 99.391  96.980  124.514 1.00 66.15  ?  296 ASP B CB  1 
ATOM   4132 C CG  . ASP B 2 302 ? 100.373 96.200  123.660 1.00 66.15  ?  296 ASP B CG  1 
ATOM   4133 O OD1 . ASP B 2 302 ? 101.150 96.831  122.913 1.00 66.15  ?  296 ASP B OD1 1 
ATOM   4134 O OD2 . ASP B 2 302 ? 100.368 94.953  123.737 1.00 66.15  ?  296 ASP B OD2 1 
ATOM   4135 N N   . PHE B 2 303 ? 98.209  99.964  122.747 1.00 65.16  ?  297 PHE B N   1 
ATOM   4136 C CA  . PHE B 2 303 ? 97.634  100.397 121.475 1.00 65.16  ?  297 PHE B CA  1 
ATOM   4137 C C   . PHE B 2 303 ? 96.495  99.475  121.041 1.00 65.16  ?  297 PHE B C   1 
ATOM   4138 O O   . PHE B 2 303 ? 96.400  99.096  119.873 1.00 65.16  ?  297 PHE B O   1 
ATOM   4139 C CB  . PHE B 2 303 ? 98.702  100.476 120.378 1.00 65.16  ?  297 PHE B CB  1 
ATOM   4140 C CG  . PHE B 2 303 ? 99.926  101.260 120.767 1.00 65.16  ?  297 PHE B CG  1 
ATOM   4141 C CD1 . PHE B 2 303 ? 99.854  102.278 121.704 1.00 65.16  ?  297 PHE B CD1 1 
ATOM   4142 C CD2 . PHE B 2 303 ? 101.153 100.977 120.189 1.00 65.16  ?  297 PHE B CD2 1 
ATOM   4143 C CE1 . PHE B 2 303 ? 100.981 102.996 122.057 1.00 65.16  ?  297 PHE B CE1 1 
ATOM   4144 C CE2 . PHE B 2 303 ? 102.282 101.692 120.538 1.00 65.16  ?  297 PHE B CE2 1 
ATOM   4145 C CZ  . PHE B 2 303 ? 102.196 102.703 121.473 1.00 65.16  ?  297 PHE B CZ  1 
ATOM   4146 N N   . ASN B 2 304 ? 95.623  99.114  121.980 1.00 65.65  ?  298 ASN B N   1 
ATOM   4147 C CA  . ASN B 2 304 ? 94.533  98.202  121.661 1.00 65.65  ?  298 ASN B CA  1 
ATOM   4148 C C   . ASN B 2 304 ? 93.563  98.124  122.831 1.00 65.65  ?  298 ASN B C   1 
ATOM   4149 O O   . ASN B 2 304 ? 93.814  98.678  123.907 1.00 65.65  ?  298 ASN B O   1 
ATOM   4150 C CB  . ASN B 2 304 ? 95.064  96.802  121.320 1.00 65.65  ?  298 ASN B CB  1 
ATOM   4151 C CG  . ASN B 2 304 ? 95.953  96.233  122.409 1.00 65.65  ?  298 ASN B CG  1 
ATOM   4152 O OD1 . ASN B 2 304 ? 95.952  96.711  123.543 1.00 65.65  ?  298 ASN B OD1 1 
ATOM   4153 N ND2 . ASN B 2 304 ? 96.718  95.203  122.067 1.00 65.65  ?  298 ASN B ND2 1 
ATOM   4154 N N   . CYS B 2 305 ? 92.448  97.443  122.594 1.00 64.23  ?  299 CYS B N   1 
ATOM   4155 C CA  . CYS B 2 305 ? 91.436  97.175  123.604 1.00 64.23  ?  299 CYS B CA  1 
ATOM   4156 C C   . CYS B 2 305 ? 91.162  95.679  123.691 1.00 64.23  ?  299 CYS B C   1 
ATOM   4157 O O   . CYS B 2 305 ? 91.333  94.935  122.723 1.00 64.23  ?  299 CYS B O   1 
ATOM   4158 C CB  . CYS B 2 305 ? 90.142  97.928  123.281 1.00 64.23  ?  299 CYS B CB  1 
ATOM   4159 S SG  . CYS B 2 305 ? 88.685  97.340  124.177 1.00 64.23  ?  299 CYS B SG  1 
ATOM   4160 N N   . ASN B 2 306 ? 90.729  95.244  124.870 1.00 64.58  ?  300 ASN B N   1 
ATOM   4161 C CA  . ASN B 2 306 ? 90.351  93.862  125.107 1.00 64.58  ?  300 ASN B CA  1 
ATOM   4162 C C   . ASN B 2 306 ? 88.908  93.804  125.589 1.00 64.58  ?  300 ASN B C   1 
ATOM   4163 O O   . ASN B 2 306 ? 88.367  94.774  126.129 1.00 64.58  ?  300 ASN B O   1 
ATOM   4164 C CB  . ASN B 2 306 ? 91.272  93.195  126.138 1.00 64.58  ?  300 ASN B CB  1 
ATOM   4165 C CG  . ASN B 2 306 ? 92.716  93.132  125.677 1.00 64.58  ?  300 ASN B CG  1 
ATOM   4166 O OD1 . ASN B 2 306 ? 93.483  94.074  125.870 1.00 64.58  ?  300 ASN B OD1 1 
ATOM   4167 N ND2 . ASN B 2 306 ? 93.094  92.014  125.068 1.00 64.58  ?  300 ASN B ND2 1 
ATOM   4168 N N   . VAL B 2 307 ? 88.289  92.644  125.381 1.00 64.27  ?  301 VAL B N   1 
ATOM   4169 C CA  . VAL B 2 307 ? 86.914  92.387  125.789 1.00 64.27  ?  301 VAL B CA  1 
ATOM   4170 C C   . VAL B 2 307 ? 86.908  91.011  126.437 1.00 64.27  ?  301 VAL B C   1 
ATOM   4171 O O   . VAL B 2 307 ? 87.065  89.998  125.745 1.00 64.27  ?  301 VAL B O   1 
ATOM   4172 C CB  . VAL B 2 307 ? 85.930  92.433  124.610 1.00 64.27  ?  301 VAL B CB  1 
ATOM   4173 C CG1 . VAL B 2 307 ? 84.494  92.292  125.110 1.00 64.27  ?  301 VAL B CG1 1 
ATOM   4174 C CG2 . VAL B 2 307 ? 86.123  93.717  123.805 1.00 64.27  ?  301 VAL B CG2 1 
ATOM   4175 N N   . TRP B 2 308 ? 86.740  90.972  127.754 1.00 66.17  ?  302 TRP B N   1 
ATOM   4176 C CA  . TRP B 2 308 ? 86.737  89.739  128.525 1.00 66.17  ?  302 TRP B CA  1 
ATOM   4177 C C   . TRP B 2 308 ? 85.315  89.397  128.950 1.00 66.17  ?  302 TRP B C   1 
ATOM   4178 O O   . TRP B 2 308 ? 84.377  90.177  128.765 1.00 66.17  ?  302 TRP B O   1 
ATOM   4179 C CB  . TRP B 2 308 ? 87.641  89.868  129.758 1.00 66.17  ?  302 TRP B CB  1 
ATOM   4180 C CG  . TRP B 2 308 ? 89.045  90.288  129.441 1.00 66.17  ?  302 TRP B CG  1 
ATOM   4181 C CD1 . TRP B 2 308 ? 89.477  91.551  129.154 1.00 66.17  ?  302 TRP B CD1 1 
ATOM   4182 C CD2 . TRP B 2 308 ? 90.203  89.446  129.387 1.00 66.17  ?  302 TRP B CD2 1 
ATOM   4183 N NE1 . TRP B 2 308 ? 90.831  91.546  128.922 1.00 66.17  ?  302 TRP B NE1 1 
ATOM   4184 C CE2 . TRP B 2 308 ? 91.301  90.267  129.059 1.00 66.17  ?  302 TRP B CE2 1 
ATOM   4185 C CE3 . TRP B 2 308 ? 90.418  88.079  129.584 1.00 66.17  ?  302 TRP B CE3 1 
ATOM   4186 C CZ2 . TRP B 2 308 ? 92.593  89.765  128.922 1.00 66.17  ?  302 TRP B CZ2 1 
ATOM   4187 C CZ3 . TRP B 2 308 ? 91.702  87.582  129.447 1.00 66.17  ?  302 TRP B CZ3 1 
ATOM   4188 C CH2 . TRP B 2 308 ? 92.773  88.423  129.119 1.00 66.17  ?  302 TRP B CH2 1 
ATOM   4189 N N   . ASP B 2 309 ? 85.166  88.213  129.536 1.00 70.41  ?  303 ASP B N   1 
ATOM   4190 C CA  . ASP B 2 309 ? 83.884  87.739  130.038 1.00 70.41  ?  303 ASP B CA  1 
ATOM   4191 C C   . ASP B 2 309 ? 83.785  88.078  131.520 1.00 70.41  ?  303 ASP B C   1 
ATOM   4192 O O   . ASP B 2 309 ? 84.609  87.623  132.321 1.00 70.41  ?  303 ASP B O   1 
ATOM   4193 C CB  . ASP B 2 309 ? 83.734  86.235  129.815 1.00 70.41  ?  303 ASP B CB  1 
ATOM   4194 C CG  . ASP B 2 309 ? 82.319  85.745  130.056 1.00 70.41  ?  303 ASP B CG  1 
ATOM   4195 O OD1 . ASP B 2 309 ? 81.597  86.369  130.862 1.00 70.41  ?  303 ASP B OD1 1 
ATOM   4196 O OD2 . ASP B 2 309 ? 81.927  84.733  129.438 1.00 70.41  ?  303 ASP B OD2 1 
ATOM   4197 N N   . ALA B 2 310 ? 82.778  88.876  131.882 1.00 69.17  ?  304 ALA B N   1 
ATOM   4198 C CA  . ALA B 2 310 ? 82.616  89.275  133.276 1.00 69.17  ?  304 ALA B CA  1 
ATOM   4199 C C   . ALA B 2 310 ? 82.490  88.069  134.196 1.00 69.17  ?  304 ALA B C   1 
ATOM   4200 O O   . ALA B 2 310 ? 82.831  88.155  135.382 1.00 69.17  ?  304 ALA B O   1 
ATOM   4201 C CB  . ALA B 2 310 ? 81.395  90.183  133.423 1.00 69.17  ?  304 ALA B CB  1 
ATOM   4202 N N   . LEU B 2 311 ? 82.006  86.940  133.676 1.00 74.14  ?  305 LEU B N   1 
ATOM   4203 C CA  . LEU B 2 311 ? 81.831  85.725  134.466 1.00 74.14  ?  305 LEU B CA  1 
ATOM   4204 C C   . LEU B 2 311 ? 82.981  84.745  134.259 1.00 74.14  ?  305 LEU B C   1 
ATOM   4205 O O   . LEU B 2 311 ? 83.631  84.332  135.224 1.00 74.14  ?  305 LEU B O   1 
ATOM   4206 C CB  . LEU B 2 311 ? 80.492  85.065  134.110 1.00 74.14  ?  305 LEU B CB  1 
ATOM   4207 C CG  . LEU B 2 311 ? 79.246  85.932  134.313 1.00 74.14  ?  305 LEU B CG  1 
ATOM   4208 C CD1 . LEU B 2 311 ? 77.999  85.189  133.861 1.00 74.14  ?  305 LEU B CD1 1 
ATOM   4209 C CD2 . LEU B 2 311 ? 79.116  86.367  135.766 1.00 74.14  ?  305 LEU B CD2 1 
ATOM   4210 N N   . LYS B 2 312 ? 83.246  84.364  133.008 1.00 74.43  ?  306 LYS B N   1 
ATOM   4211 C CA  . LYS B 2 312 ? 84.311  83.412  132.717 1.00 74.43  ?  306 LYS B CA  1 
ATOM   4212 C C   . LYS B 2 312 ? 85.701  84.025  132.835 1.00 74.43  ?  306 LYS B C   1 
ATOM   4213 O O   . LYS B 2 312 ? 86.666  83.290  133.074 1.00 74.43  ?  306 LYS B O   1 
ATOM   4214 C CB  . LYS B 2 312 ? 84.130  82.836  131.310 1.00 74.43  ?  306 LYS B CB  1 
ATOM   4215 C CG  . LYS B 2 312 ? 82.903  81.947  131.151 1.00 74.43  ?  306 LYS B CG  1 
ATOM   4216 C CD  . LYS B 2 312 ? 83.086  80.591  131.821 1.00 74.43  ?  306 LYS B CD  1 
ATOM   4217 C CE  . LYS B 2 312 ? 84.055  79.705  131.051 1.00 74.43  ?  306 LYS B CE  1 
ATOM   4218 N NZ  . LYS B 2 312 ? 84.179  78.353  131.662 1.00 74.43  1  306 LYS B NZ  1 
ATOM   4219 N N   . ALA B 2 313 ? 85.827  85.341  132.670 1.00 70.06  ?  307 ALA B N   1 
ATOM   4220 C CA  . ALA B 2 313 ? 87.092  86.066  132.746 1.00 70.06  ?  307 ALA B CA  1 
ATOM   4221 C C   . ALA B 2 313 ? 88.050  85.697  131.622 1.00 70.06  ?  307 ALA B C   1 
ATOM   4222 O O   . ALA B 2 313 ? 89.236  86.043  131.691 1.00 70.06  ?  307 ALA B O   1 
ATOM   4223 C CB  . ALA B 2 313 ? 87.789  85.846  134.094 1.00 70.06  ?  307 ALA B CB  1 
ATOM   4224 N N   . ASP B 2 314 ? 87.575  85.008  130.588 1.00 69.46  ?  308 ASP B N   1 
ATOM   4225 C CA  . ASP B 2 314 ? 88.427  84.624  129.475 1.00 69.46  ?  308 ASP B CA  1 
ATOM   4226 C C   . ASP B 2 314 ? 88.431  85.710  128.402 1.00 69.46  ?  308 ASP B C   1 
ATOM   4227 O O   . ASP B 2 314 ? 87.499  86.509  128.283 1.00 69.46  ?  308 ASP B O   1 
ATOM   4228 C CB  . ASP B 2 314 ? 87.962  83.298  128.874 1.00 69.46  ?  308 ASP B CB  1 
ATOM   4229 C CG  . ASP B 2 314 ? 87.983  82.163  129.879 1.00 69.46  ?  308 ASP B CG  1 
ATOM   4230 O OD1 . ASP B 2 314 ? 88.830  82.196  130.797 1.00 69.46  ?  308 ASP B OD1 1 
ATOM   4231 O OD2 . ASP B 2 314 ? 87.153  81.239  129.752 1.00 69.46  ?  308 ASP B OD2 1 
ATOM   4232 N N   . ARG B 2 315 ? 89.504  85.729  127.615 1.00 65.78  ?  309 ARG B N   1 
ATOM   4233 C CA  . ARG B 2 315 ? 89.645  86.703  126.538 1.00 65.78  ?  309 ARG B CA  1 
ATOM   4234 C C   . ARG B 2 315 ? 88.630  86.395  125.444 1.00 65.78  ?  309 ARG B C   1 
ATOM   4235 O O   . ARG B 2 315 ? 88.786  85.425  124.696 1.00 65.78  ?  309 ARG B O   1 
ATOM   4236 C CB  . ARG B 2 315 ? 91.068  86.677  125.986 1.00 65.78  ?  309 ARG B CB  1 
ATOM   4237 C CG  . ARG B 2 315 ? 91.308  87.654  124.845 1.00 65.78  ?  309 ARG B CG  1 
ATOM   4238 C CD  . ARG B 2 315 ? 92.753  87.617  124.374 1.00 65.78  ?  309 ARG B CD  1 
ATOM   4239 N NE  . ARG B 2 315 ? 93.682  88.044  125.416 1.00 65.78  ?  309 ARG B NE  1 
ATOM   4240 C CZ  . ARG B 2 315 ? 94.999  88.133  125.255 1.00 65.78  ?  309 ARG B CZ  1 
ATOM   4241 N NH1 . ARG B 2 315 ? 95.554  87.825  124.090 1.00 65.78  1  309 ARG B NH1 1 
ATOM   4242 N NH2 . ARG B 2 315 ? 95.764  88.531  126.262 1.00 65.78  ?  309 ARG B NH2 1 
ATOM   4243 N N   . ALA B 2 316 ? 87.589  87.221  125.348 1.00 66.33  ?  310 ALA B N   1 
ATOM   4244 C CA  . ALA B 2 316 ? 86.550  87.022  124.346 1.00 66.33  ?  310 ALA B CA  1 
ATOM   4245 C C   . ALA B 2 316 ? 86.854  87.728  123.033 1.00 66.33  ?  310 ALA B C   1 
ATOM   4246 O O   . ALA B 2 316 ? 86.493  87.216  121.967 1.00 66.33  ?  310 ALA B O   1 
ATOM   4247 C CB  . ALA B 2 316 ? 85.201  87.508  124.882 1.00 66.33  ?  310 ALA B CB  1 
ATOM   4248 N N   . GLY B 2 317 ? 87.504  88.885  123.079 1.00 63.62  ?  311 GLY B N   1 
ATOM   4249 C CA  . GLY B 2 317 ? 87.799  89.612  121.858 1.00 63.62  ?  311 GLY B CA  1 
ATOM   4250 C C   . GLY B 2 317 ? 88.914  90.610  122.059 1.00 63.62  ?  311 GLY B C   1 
ATOM   4251 O O   . GLY B 2 317 ? 89.214  91.022  123.184 1.00 63.62  ?  311 GLY B O   1 
ATOM   4252 N N   . VAL B 2 318 ? 89.518  91.006  120.941 1.00 63.77  ?  312 VAL B N   1 
ATOM   4253 C CA  . VAL B 2 318 ? 90.602  91.981  120.931 1.00 63.77  ?  312 VAL B CA  1 
ATOM   4254 C C   . VAL B 2 318 ? 90.384  92.939  119.768 1.00 63.77  ?  312 VAL B C   1 
ATOM   4255 O O   . VAL B 2 318 ? 90.082  92.515  118.647 1.00 63.77  ?  312 VAL B O   1 
ATOM   4256 C CB  . VAL B 2 318 ? 91.982  91.299  120.827 1.00 63.77  ?  312 VAL B CB  1 
ATOM   4257 C CG1 . VAL B 2 318 ? 92.226  90.409  122.036 1.00 63.77  ?  312 VAL B CG1 1 
ATOM   4258 C CG2 . VAL B 2 318 ? 92.091  90.495  119.536 1.00 63.77  ?  312 VAL B CG2 1 
ATOM   4259 N N   . LEU B 2 319 ? 90.536  94.233  120.038 1.00 63.51  ?  313 LEU B N   1 
ATOM   4260 C CA  . LEU B 2 319 ? 90.378  95.289  119.040 1.00 63.51  ?  313 LEU B CA  1 
ATOM   4261 C C   . LEU B 2 319 ? 91.729  95.981  118.891 1.00 63.51  ?  313 LEU B C   1 
ATOM   4262 O O   . LEU B 2 319 ? 92.172  96.693  119.799 1.00 63.51  ?  313 LEU B O   1 
ATOM   4263 C CB  . LEU B 2 319 ? 89.289  96.279  119.447 1.00 63.51  ?  313 LEU B CB  1 
ATOM   4264 C CG  . LEU B 2 319 ? 87.845  95.771  119.511 1.00 63.51  ?  313 LEU B CG  1 
ATOM   4265 C CD1 . LEU B 2 319 ? 87.665  94.728  120.605 1.00 63.51  ?  313 LEU B CD1 1 
ATOM   4266 C CD2 . LEU B 2 319 ? 86.889  96.934  119.727 1.00 63.51  ?  313 LEU B CD2 1 
ATOM   4267 N N   . ALA B 2 320 ? 92.385  95.764  117.751 1.00 64.90  ?  314 ALA B N   1 
ATOM   4268 C CA  . ALA B 2 320 ? 93.693  96.340  117.466 1.00 64.90  ?  314 ALA B CA  1 
ATOM   4269 C C   . ALA B 2 320 ? 93.664  97.229  116.226 1.00 64.90  ?  314 ALA B C   1 
ATOM   4270 O O   . ALA B 2 320 ? 94.656  97.326  115.500 1.00 64.90  ?  314 ALA B O   1 
ATOM   4271 C CB  . ALA B 2 320 ? 94.735  95.235  117.302 1.00 64.90  ?  314 ALA B CB  1 
ATOM   4272 N N   . GLY B 2 321 ? 92.533  97.883  115.972 1.00 61.69  ?  315 GLY B N   1 
ATOM   4273 C CA  . GLY B 2 321 ? 92.407  98.745  114.814 1.00 61.69  ?  315 GLY B CA  1 
ATOM   4274 C C   . GLY B 2 321 ? 93.157  100.051 114.968 1.00 61.69  ?  315 GLY B C   1 
ATOM   4275 O O   . GLY B 2 321 ? 93.703  100.579 113.995 1.00 61.69  ?  315 GLY B O   1 
ATOM   4276 N N   . HIS B 2 322 ? 93.194  100.581 116.188 1.00 61.93  ?  316 HIS B N   1 
ATOM   4277 C CA  . HIS B 2 322 ? 93.890  101.831 116.439 1.00 61.93  ?  316 HIS B CA  1 
ATOM   4278 C C   . HIS B 2 322 ? 95.399  101.640 116.291 1.00 61.93  ?  316 HIS B C   1 
ATOM   4279 O O   . HIS B 2 322 ? 95.915  100.519 116.251 1.00 61.93  ?  316 HIS B O   1 
ATOM   4280 C CB  . HIS B 2 322 ? 93.557  102.357 117.835 1.00 61.93  ?  316 HIS B CB  1 
ATOM   4281 C CG  . HIS B 2 322 ? 92.101  102.631 118.045 1.00 61.93  ?  316 HIS B CG  1 
ATOM   4282 N ND1 . HIS B 2 322 ? 91.525  103.853 117.769 1.00 61.93  ?  316 HIS B ND1 1 
ATOM   4283 C CD2 . HIS B 2 322 ? 91.103  101.841 118.506 1.00 61.93  ?  316 HIS B CD2 1 
ATOM   4284 C CE1 . HIS B 2 322 ? 90.235  103.803 118.050 1.00 61.93  ?  316 HIS B CE1 1 
ATOM   4285 N NE2 . HIS B 2 322 ? 89.953  102.593 118.499 1.00 61.93  ?  316 HIS B NE2 1 
ATOM   4286 N N   . ASP B 2 323 ? 96.111  102.765 116.209 1.00 64.13  ?  317 ASP B N   1 
ATOM   4287 C CA  . ASP B 2 323 ? 97.559  102.764 116.071 1.00 64.13  ?  317 ASP B CA  1 
ATOM   4288 C C   . ASP B 2 323 ? 98.282  103.428 117.234 1.00 64.13  ?  317 ASP B C   1 
ATOM   4289 O O   . ASP B 2 323 ? 99.511  103.313 117.316 1.00 64.13  ?  317 ASP B O   1 
ATOM   4290 C CB  . ASP B 2 323 ? 97.972  103.465 114.767 1.00 64.13  ?  317 ASP B CB  1 
ATOM   4291 C CG  . ASP B 2 323 ? 97.521  104.912 114.714 1.00 64.13  ?  317 ASP B CG  1 
ATOM   4292 O OD1 . ASP B 2 323 ? 98.122  105.750 115.418 1.00 64.13  ?  317 ASP B OD1 1 
ATOM   4293 O OD2 . ASP B 2 323 ? 96.565  105.211 113.968 1.00 64.13  ?  317 ASP B OD2 1 
ATOM   4294 N N   . ASN B 2 324 ? 97.570  104.111 118.126 1.00 62.76  ?  318 ASN B N   1 
ATOM   4295 C CA  . ASN B 2 324 ? 98.166  104.795 119.265 1.00 62.76  ?  318 ASN B CA  1 
ATOM   4296 C C   . ASN B 2 324 ? 97.492  104.305 120.543 1.00 62.76  ?  318 ASN B C   1 
ATOM   4297 O O   . ASN B 2 324 ? 96.552  103.505 120.510 1.00 62.76  ?  318 ASN B O   1 
ATOM   4298 C CB  . ASN B 2 324 ? 98.038  106.317 119.118 1.00 62.76  ?  318 ASN B CB  1 
ATOM   4299 C CG  . ASN B 2 324 ? 99.057  107.073 119.950 1.00 62.76  ?  318 ASN B CG  1 
ATOM   4300 O OD1 . ASN B 2 324 ? 99.498  106.597 120.996 1.00 62.76  ?  318 ASN B OD1 1 
ATOM   4301 N ND2 . ASN B 2 324 ? 99.437  108.258 119.486 1.00 62.76  ?  318 ASN B ND2 1 
ATOM   4302 N N   . ARG B 2 325 ? 97.984  104.791 121.681 1.00 62.71  ?  319 ARG B N   1 
ATOM   4303 C CA  . ARG B 2 325 ? 97.451  104.379 122.973 1.00 62.71  ?  319 ARG B CA  1 
ATOM   4304 C C   . ARG B 2 325 ? 95.976  104.744 123.081 1.00 62.71  ?  319 ARG B C   1 
ATOM   4305 O O   . ARG B 2 325 ? 95.607  105.917 122.967 1.00 62.71  ?  319 ARG B O   1 
ATOM   4306 C CB  . ARG B 2 325 ? 98.249  105.038 124.096 1.00 62.71  ?  319 ARG B CB  1 
ATOM   4307 C CG  . ARG B 2 325 ? 97.863  104.576 125.492 1.00 62.71  ?  319 ARG B CG  1 
ATOM   4308 C CD  . ARG B 2 325 ? 97.298  105.716 126.325 1.00 62.71  ?  319 ARG B CD  1 
ATOM   4309 N NE  . ARG B 2 325 ? 97.122  105.334 127.724 1.00 62.71  ?  319 ARG B NE  1 
ATOM   4310 C CZ  . ARG B 2 325 ? 96.623  106.132 128.663 1.00 62.71  ?  319 ARG B CZ  1 
ATOM   4311 N NH1 . ARG B 2 325 ? 96.241  107.365 128.362 1.00 62.71  1  319 ARG B NH1 1 
ATOM   4312 N NH2 . ARG B 2 325 ? 96.504  105.693 129.909 1.00 62.71  ?  319 ARG B NH2 1 
ATOM   4313 N N   . VAL B 2 326 ? 95.134  103.734 123.302 1.00 62.22  ?  320 VAL B N   1 
ATOM   4314 C CA  . VAL B 2 326 ? 93.706  103.973 123.470 1.00 62.22  ?  320 VAL B CA  1 
ATOM   4315 C C   . VAL B 2 326 ? 93.485  104.798 124.730 1.00 62.22  ?  320 VAL B C   1 
ATOM   4316 O O   . VAL B 2 326 ? 94.073  104.523 125.784 1.00 62.22  ?  320 VAL B O   1 
ATOM   4317 C CB  . VAL B 2 326 ? 92.940  102.644 123.534 1.00 62.22  ?  320 VAL B CB  1 
ATOM   4318 C CG1 . VAL B 2 326 ? 93.283  101.894 124.814 1.00 62.22  ?  320 VAL B CG1 1 
ATOM   4319 C CG2 . VAL B 2 326 ? 91.438  102.887 123.423 1.00 62.22  ?  320 VAL B CG2 1 
ATOM   4320 N N   . SER B 2 327 ? 92.634  105.816 124.627 1.00 61.87  ?  321 SER B N   1 
ATOM   4321 C CA  . SER B 2 327 ? 92.376  106.729 125.733 1.00 61.87  ?  321 SER B CA  1 
ATOM   4322 C C   . SER B 2 327 ? 91.038  106.481 126.414 1.00 61.87  ?  321 SER B C   1 
ATOM   4323 O O   . SER B 2 327 ? 90.950  106.579 127.641 1.00 61.87  ?  321 SER B O   1 
ATOM   4324 C CB  . SER B 2 327 ? 92.430  108.178 125.243 1.00 61.87  ?  321 SER B CB  1 
ATOM   4325 O OG  . SER B 2 327 ? 92.399  109.082 126.333 1.00 61.87  ?  321 SER B OG  1 
ATOM   4326 N N   . CYS B 2 328 ? 89.991  106.165 125.654 1.00 61.46  ?  322 CYS B N   1 
ATOM   4327 C CA  . CYS B 2 328 ? 88.672  105.982 126.240 1.00 61.46  ?  322 CYS B CA  1 
ATOM   4328 C C   . CYS B 2 328 ? 87.835  105.083 125.343 1.00 61.46  ?  322 CYS B C   1 
ATOM   4329 O O   . CYS B 2 328 ? 88.102  104.938 124.149 1.00 61.46  ?  322 CYS B O   1 
ATOM   4330 C CB  . CYS B 2 328 ? 87.971  107.328 126.454 1.00 61.46  ?  322 CYS B CB  1 
ATOM   4331 S SG  . CYS B 2 328 ? 87.954  108.390 124.991 1.00 61.46  ?  322 CYS B SG  1 
ATOM   4332 N N   . LEU B 2 329 ? 86.809  104.481 125.941 1.00 61.56  ?  323 LEU B N   1 
ATOM   4333 C CA  . LEU B 2 329 ? 85.874  103.644 125.205 1.00 61.56  ?  323 LEU B CA  1 
ATOM   4334 C C   . LEU B 2 329 ? 84.530  103.663 125.917 1.00 61.56  ?  323 LEU B C   1 
ATOM   4335 O O   . LEU B 2 329 ? 84.445  103.922 127.120 1.00 61.56  ?  323 LEU B O   1 
ATOM   4336 C CB  . LEU B 2 329 ? 86.395  102.207 125.056 1.00 61.56  ?  323 LEU B CB  1 
ATOM   4337 C CG  . LEU B 2 329 ? 86.880  101.480 126.314 1.00 61.56  ?  323 LEU B CG  1 
ATOM   4338 C CD1 . LEU B 2 329 ? 85.729  101.122 127.244 1.00 61.56  ?  323 LEU B CD1 1 
ATOM   4339 C CD2 . LEU B 2 329 ? 87.662  100.233 125.929 1.00 61.56  ?  323 LEU B CD2 1 
ATOM   4340 N N   . GLY B 2 330 ? 83.476  103.393 125.152 1.00 60.81  ?  324 GLY B N   1 
ATOM   4341 C CA  . GLY B 2 330 ? 82.132  103.407 125.695 1.00 60.81  ?  324 GLY B CA  1 
ATOM   4342 C C   . GLY B 2 330 ? 81.135  102.596 124.893 1.00 60.81  ?  324 GLY B C   1 
ATOM   4343 O O   . GLY B 2 330 ? 81.153  102.610 123.657 1.00 60.81  ?  324 GLY B O   1 
ATOM   4344 N N   . VAL B 2 331 ? 80.250  101.893 125.594 1.00 61.40  ?  325 VAL B N   1 
ATOM   4345 C CA  . VAL B 2 331 ? 79.213  101.074 124.978 1.00 61.40  ?  325 VAL B CA  1 
ATOM   4346 C C   . VAL B 2 331 ? 77.917  101.870 124.942 1.00 61.40  ?  325 VAL B C   1 
ATOM   4347 O O   . VAL B 2 331 ? 77.595  102.600 125.888 1.00 61.40  ?  325 VAL B O   1 
ATOM   4348 C CB  . VAL B 2 331 ? 79.023  99.750  125.744 1.00 61.40  ?  325 VAL B CB  1 
ATOM   4349 C CG1 . VAL B 2 331 ? 77.956  98.895  125.076 1.00 61.40  ?  325 VAL B CG1 1 
ATOM   4350 C CG2 . VAL B 2 331 ? 80.341  98.996  125.837 1.00 61.40  ?  325 VAL B CG2 1 
ATOM   4351 N N   . THR B 2 332 ? 77.173  101.733 123.848 1.00 61.78  ?  326 THR B N   1 
ATOM   4352 C CA  . THR B 2 332 ? 75.901  102.426 123.719 1.00 61.78  ?  326 THR B CA  1 
ATOM   4353 C C   . THR B 2 332 ? 74.917  101.938 124.779 1.00 61.78  ?  326 THR B C   1 
ATOM   4354 O O   . THR B 2 332 ? 75.034  100.833 125.317 1.00 61.78  ?  326 THR B O   1 
ATOM   4355 C CB  . THR B 2 332 ? 75.308  102.211 122.326 1.00 61.78  ?  326 THR B CB  1 
ATOM   4356 O OG1 . THR B 2 332 ? 75.090  100.811 122.106 1.00 61.78  ?  326 THR B OG1 1 
ATOM   4357 C CG2 . THR B 2 332 ? 76.241  102.752 121.253 1.00 61.78  ?  326 THR B CG2 1 
ATOM   4358 N N   . ASP B 2 333 ? 73.931  102.787 125.079 1.00 62.58  ?  327 ASP B N   1 
ATOM   4359 C CA  . ASP B 2 333 ? 72.901  102.404 126.039 1.00 62.58  ?  327 ASP B CA  1 
ATOM   4360 C C   . ASP B 2 333 ? 72.123  101.184 125.565 1.00 62.58  ?  327 ASP B C   1 
ATOM   4361 O O   . ASP B 2 333 ? 71.614  100.414 126.387 1.00 62.58  ?  327 ASP B O   1 
ATOM   4362 C CB  . ASP B 2 333 ? 71.949  103.575 126.284 1.00 62.58  ?  327 ASP B CB  1 
ATOM   4363 C CG  . ASP B 2 333 ? 72.643  104.769 126.910 1.00 62.58  ?  327 ASP B CG  1 
ATOM   4364 O OD1 . ASP B 2 333 ? 73.673  104.572 127.589 1.00 62.58  ?  327 ASP B OD1 1 
ATOM   4365 O OD2 . ASP B 2 333 ? 72.156  105.904 126.726 1.00 62.58  ?  327 ASP B OD2 1 
ATOM   4366 N N   . ASP B 2 334 ? 72.021  100.991 124.250 1.00 63.13  ?  328 ASP B N   1 
ATOM   4367 C CA  . ASP B 2 334 ? 71.331  99.842  123.681 1.00 63.13  ?  328 ASP B CA  1 
ATOM   4368 C C   . ASP B 2 334 ? 72.276  98.715  123.285 1.00 63.13  ?  328 ASP B C   1 
ATOM   4369 O O   . ASP B 2 334 ? 71.806  97.618  122.964 1.00 63.13  ?  328 ASP B O   1 
ATOM   4370 C CB  . ASP B 2 334 ? 70.511  100.271 122.456 1.00 63.13  ?  328 ASP B CB  1 
ATOM   4371 C CG  . ASP B 2 334 ? 71.349  100.983 121.412 1.00 63.13  ?  328 ASP B CG  1 
ATOM   4372 O OD1 . ASP B 2 334 ? 72.565  101.157 121.641 1.00 63.13  ?  328 ASP B OD1 1 
ATOM   4373 O OD2 . ASP B 2 334 ? 70.792  101.368 120.363 1.00 63.13  ?  328 ASP B OD2 1 
ATOM   4374 N N   . GLY B 2 335 ? 73.586  98.953  123.298 1.00 63.10  ?  329 GLY B N   1 
ATOM   4375 C CA  . GLY B 2 335 ? 74.543  97.907  123.001 1.00 63.10  ?  329 GLY B CA  1 
ATOM   4376 C C   . GLY B 2 335 ? 74.688  97.567  121.537 1.00 63.10  ?  329 GLY B C   1 
ATOM   4377 O O   . GLY B 2 335 ? 75.153  96.469  121.213 1.00 63.10  ?  329 GLY B O   1 
ATOM   4378 N N   . MET B 2 336 ? 74.308  98.473  120.634 1.00 64.37  ?  330 MET B N   1 
ATOM   4379 C CA  . MET B 2 336 ? 74.424  98.183  119.209 1.00 64.37  ?  330 MET B CA  1 
ATOM   4380 C C   . MET B 2 336 ? 75.876  98.236  118.749 1.00 64.37  ?  330 MET B C   1 
ATOM   4381 O O   . MET B 2 336 ? 76.293  97.436  117.903 1.00 64.37  ?  330 MET B O   1 
ATOM   4382 C CB  . MET B 2 336 ? 73.571  99.163  118.403 1.00 64.37  ?  330 MET B CB  1 
ATOM   4383 C CG  . MET B 2 336 ? 72.073  99.007  118.620 1.00 64.37  ?  330 MET B CG  1 
ATOM   4384 S SD  . MET B 2 336 ? 71.435  97.407  118.084 1.00 64.37  ?  330 MET B SD  1 
ATOM   4385 C CE  . MET B 2 336 ? 71.775  97.469  116.326 1.00 64.37  ?  330 MET B CE  1 
ATOM   4386 N N   . ALA B 2 337 ? 76.658  99.167  119.289 1.00 61.61  ?  331 ALA B N   1 
ATOM   4387 C CA  . ALA B 2 337 ? 78.056  99.314  118.910 1.00 61.61  ?  331 ALA B CA  1 
ATOM   4388 C C   . ALA B 2 337 ? 78.834  99.847  120.106 1.00 61.61  ?  331 ALA B C   1 
ATOM   4389 O O   . ALA B 2 337 ? 78.268  100.135 121.165 1.00 61.61  ?  331 ALA B O   1 
ATOM   4390 C CB  . ALA B 2 337 ? 78.201  100.234 117.694 1.00 61.61  ?  331 ALA B CB  1 
ATOM   4391 N N   . VAL B 2 338 ? 80.148  99.974  119.930 1.00 60.53  ?  332 VAL B N   1 
ATOM   4392 C CA  . VAL B 2 338 ? 81.045  100.471 120.966 1.00 60.53  ?  332 VAL B CA  1 
ATOM   4393 C C   . VAL B 2 338 ? 82.007  101.463 120.330 1.00 60.53  ?  332 VAL B C   1 
ATOM   4394 O O   . VAL B 2 338 ? 82.668  101.142 119.337 1.00 60.53  ?  332 VAL B O   1 
ATOM   4395 C CB  . VAL B 2 338 ? 81.827  99.329  121.643 1.00 60.53  ?  332 VAL B CB  1 
ATOM   4396 C CG1 . VAL B 2 338 ? 82.681  99.870  122.784 1.00 60.53  ?  332 VAL B CG1 1 
ATOM   4397 C CG2 . VAL B 2 338 ? 80.875  98.253  122.143 1.00 60.53  ?  332 VAL B CG2 1 
ATOM   4398 N N   . ALA B 2 339 ? 82.089  102.660 120.901 1.00 59.58  ?  333 ALA B N   1 
ATOM   4399 C CA  . ALA B 2 339 ? 83.011  103.675 120.418 1.00 59.58  ?  333 ALA B CA  1 
ATOM   4400 C C   . ALA B 2 339 ? 84.317  103.614 121.200 1.00 59.58  ?  333 ALA B C   1 
ATOM   4401 O O   . ALA B 2 339 ? 84.335  103.288 122.389 1.00 59.58  ?  333 ALA B O   1 
ATOM   4402 C CB  . ALA B 2 339 ? 82.394  105.069 120.538 1.00 59.58  ?  333 ALA B CB  1 
ATOM   4403 N N   . THR B 2 340 ? 85.416  103.926 120.515 1.00 59.91  ?  334 THR B N   1 
ATOM   4404 C CA  . THR B 2 340 ? 86.743  103.898 121.120 1.00 59.91  ?  334 THR B CA  1 
ATOM   4405 C C   . THR B 2 340 ? 87.563  105.047 120.555 1.00 59.91  ?  334 THR B C   1 
ATOM   4406 O O   . THR B 2 340 ? 87.753  105.135 119.337 1.00 59.91  ?  334 THR B O   1 
ATOM   4407 C CB  . THR B 2 340 ? 87.447  102.563 120.855 1.00 59.91  ?  334 THR B CB  1 
ATOM   4408 O OG1 . THR B 2 340 ? 87.610  102.376 119.443 1.00 59.91  ?  334 THR B OG1 1 
ATOM   4409 C CG2 . THR B 2 340 ? 86.641  101.405 121.427 1.00 59.91  ?  334 THR B CG2 1 
ATOM   4410 N N   . GLY B 2 341 ? 88.043  105.919 121.437 1.00 61.51  ?  335 GLY B N   1 
ATOM   4411 C CA  . GLY B 2 341 ? 88.886  107.040 121.059 1.00 61.51  ?  335 GLY B CA  1 
ATOM   4412 C C   . GLY B 2 341 ? 90.289  106.858 121.612 1.00 61.51  ?  335 GLY B C   1 
ATOM   4413 O O   . GLY B 2 341 ? 90.472  106.623 122.810 1.00 61.51  ?  335 GLY B O   1 
ATOM   4414 N N   . SER B 2 342 ? 91.270  106.968 120.723 1.00 61.34  ?  336 SER B N   1 
ATOM   4415 C CA  . SER B 2 342 ? 92.677  106.790 121.051 1.00 61.34  ?  336 SER B CA  1 
ATOM   4416 C C   . SER B 2 342 ? 93.435  108.089 120.791 1.00 61.34  ?  336 SER B C   1 
ATOM   4417 O O   . SER B 2 342 ? 92.876  109.080 120.315 1.00 61.34  ?  336 SER B O   1 
ATOM   4418 C CB  . SER B 2 342 ? 93.280  105.638 120.242 1.00 61.34  ?  336 SER B CB  1 
ATOM   4419 O OG  . SER B 2 342 ? 94.656  105.472 120.538 1.00 61.34  ?  336 SER B OG  1 
ATOM   4420 N N   . TRP B 2 343 ? 94.729  108.073 121.113 1.00 61.32  ?  337 TRP B N   1 
ATOM   4421 C CA  . TRP B 2 343 ? 95.590  109.226 120.884 1.00 61.32  ?  337 TRP B CA  1 
ATOM   4422 C C   . TRP B 2 343 ? 95.962  109.409 119.419 1.00 61.32  ?  337 TRP B C   1 
ATOM   4423 O O   . TRP B 2 343 ? 96.698  110.350 119.102 1.00 61.32  ?  337 TRP B O   1 
ATOM   4424 C CB  . TRP B 2 343 ? 96.865  109.100 121.723 1.00 61.32  ?  337 TRP B CB  1 
ATOM   4425 C CG  . TRP B 2 343 ? 96.656  109.338 123.190 1.00 61.32  ?  337 TRP B CG  1 
ATOM   4426 C CD1 . TRP B 2 343 ? 95.478  109.617 123.818 1.00 61.32  ?  337 TRP B CD1 1 
ATOM   4427 C CD2 . TRP B 2 343 ? 97.660  109.319 124.212 1.00 61.32  ?  337 TRP B CD2 1 
ATOM   4428 N NE1 . TRP B 2 343 ? 95.685  109.773 125.167 1.00 61.32  ?  337 TRP B NE1 1 
ATOM   4429 C CE2 . TRP B 2 343 ? 97.016  109.595 125.435 1.00 61.32  ?  337 TRP B CE2 1 
ATOM   4430 C CE3 . TRP B 2 343 ? 99.040  109.096 124.212 1.00 61.32  ?  337 TRP B CE3 1 
ATOM   4431 C CZ2 . TRP B 2 343 ? 97.705  109.654 126.644 1.00 61.32  ?  337 TRP B CZ2 1 
ATOM   4432 C CZ3 . TRP B 2 343 ? 99.722  109.154 125.414 1.00 61.32  ?  337 TRP B CZ3 1 
ATOM   4433 C CH2 . TRP B 2 343 ? 99.054  109.431 126.613 1.00 61.32  ?  337 TRP B CH2 1 
ATOM   4434 N N   . ASP B 2 344 ? 95.480  108.548 118.525 1.00 62.49  ?  338 ASP B N   1 
ATOM   4435 C CA  . ASP B 2 344 ? 95.758  108.671 117.100 1.00 62.49  ?  338 ASP B CA  1 
ATOM   4436 C C   . ASP B 2 344 ? 94.827  109.653 116.398 1.00 62.49  ?  338 ASP B C   1 
ATOM   4437 O O   . ASP B 2 344 ? 94.794  109.675 115.163 1.00 62.49  ?  338 ASP B O   1 
ATOM   4438 C CB  . ASP B 2 344 ? 95.662  107.299 116.427 1.00 62.49  ?  338 ASP B CB  1 
ATOM   4439 C CG  . ASP B 2 344 ? 94.288  106.672 116.571 1.00 62.49  ?  338 ASP B CG  1 
ATOM   4440 O OD1 . ASP B 2 344 ? 93.427  107.269 117.250 1.00 62.49  ?  338 ASP B OD1 1 
ATOM   4441 O OD2 . ASP B 2 344 ? 94.070  105.580 116.006 1.00 62.49  ?  338 ASP B OD2 1 
ATOM   4442 N N   . SER B 2 345 ? 94.073  110.455 117.149 1.00 60.86  ?  339 SER B N   1 
ATOM   4443 C CA  . SER B 2 345 ? 93.136  111.426 116.591 1.00 60.86  ?  339 SER B CA  1 
ATOM   4444 C C   . SER B 2 345 ? 92.043  110.762 115.760 1.00 60.86  ?  339 SER B C   1 
ATOM   4445 O O   . SER B 2 345 ? 91.364  111.432 114.975 1.00 60.86  ?  339 SER B O   1 
ATOM   4446 C CB  . SER B 2 345 ? 93.867  112.476 115.746 1.00 60.86  ?  339 SER B CB  1 
ATOM   4447 O OG  . SER B 2 345 ? 94.880  113.120 116.498 1.00 60.86  ?  339 SER B OG  1 
ATOM   4448 N N   . PHE B 2 346 ? 91.856  109.453 115.921 1.00 59.82  ?  340 PHE B N   1 
ATOM   4449 C CA  . PHE B 2 346 ? 90.876  108.693 115.153 1.00 59.82  ?  340 PHE B CA  1 
ATOM   4450 C C   . PHE B 2 346 ? 90.004  107.906 116.119 1.00 59.82  ?  340 PHE B C   1 
ATOM   4451 O O   . PHE B 2 346 ? 90.515  107.105 116.908 1.00 59.82  ?  340 PHE B O   1 
ATOM   4452 C CB  . PHE B 2 346 ? 91.563  107.746 114.163 1.00 59.82  ?  340 PHE B CB  1 
ATOM   4453 C CG  . PHE B 2 346 ? 92.490  108.437 113.200 1.00 59.82  ?  340 PHE B CG  1 
ATOM   4454 C CD1 . PHE B 2 346 ? 92.201  109.704 112.721 1.00 59.82  ?  340 PHE B CD1 1 
ATOM   4455 C CD2 . PHE B 2 346 ? 93.652  107.815 112.775 1.00 59.82  ?  340 PHE B CD2 1 
ATOM   4456 C CE1 . PHE B 2 346 ? 93.054  110.337 111.836 1.00 59.82  ?  340 PHE B CE1 1 
ATOM   4457 C CE2 . PHE B 2 346 ? 94.508  108.443 111.891 1.00 59.82  ?  340 PHE B CE2 1 
ATOM   4458 C CZ  . PHE B 2 346 ? 94.208  109.706 111.421 1.00 59.82  ?  340 PHE B CZ  1 
ATOM   4459 N N   . LEU B 2 347 ? 88.696  108.134 116.054 1.00 58.74  ?  341 LEU B N   1 
ATOM   4460 C CA  . LEU B 2 347 ? 87.726  107.406 116.861 1.00 58.74  ?  341 LEU B CA  1 
ATOM   4461 C C   . LEU B 2 347 ? 87.077  106.333 115.998 1.00 58.74  ?  341 LEU B C   1 
ATOM   4462 O O   . LEU B 2 347 ? 86.634  106.614 114.880 1.00 58.74  ?  341 LEU B O   1 
ATOM   4463 C CB  . LEU B 2 347 ? 86.668  108.355 117.427 1.00 58.74  ?  341 LEU B CB  1 
ATOM   4464 C CG  . LEU B 2 347 ? 85.778  107.829 118.558 1.00 58.74  ?  341 LEU B CG  1 
ATOM   4465 C CD1 . LEU B 2 347 ? 85.012  108.977 119.199 1.00 58.74  ?  341 LEU B CD1 1 
ATOM   4466 C CD2 . LEU B 2 347 ? 84.813  106.761 118.064 1.00 58.74  ?  341 LEU B CD2 1 
ATOM   4467 N N   . LYS B 2 348 ? 87.023  105.109 116.518 1.00 59.61  ?  342 LYS B N   1 
ATOM   4468 C CA  . LYS B 2 348 ? 86.517  103.961 115.776 1.00 59.61  ?  342 LYS B CA  1 
ATOM   4469 C C   . LYS B 2 348 ? 85.306  103.375 116.486 1.00 59.61  ?  342 LYS B C   1 
ATOM   4470 O O   . LYS B 2 348 ? 85.318  103.207 117.710 1.00 59.61  ?  342 LYS B O   1 
ATOM   4471 C CB  . LYS B 2 348 ? 87.602  102.892 115.615 1.00 59.61  ?  342 LYS B CB  1 
ATOM   4472 C CG  . LYS B 2 348 ? 88.788  103.340 114.776 1.00 59.61  ?  342 LYS B CG  1 
ATOM   4473 C CD  . LYS B 2 348 ? 89.794  102.217 114.589 1.00 59.61  ?  342 LYS B CD  1 
ATOM   4474 C CE  . LYS B 2 348 ? 90.966  102.658 113.724 1.00 59.61  ?  342 LYS B CE  1 
ATOM   4475 N NZ  . LYS B 2 348 ? 90.535  103.064 112.358 1.00 59.61  1  342 LYS B NZ  1 
ATOM   4476 N N   . ILE B 2 349 ? 84.267  103.065 115.715 1.00 58.32  ?  343 ILE B N   1 
ATOM   4477 C CA  . ILE B 2 349 ? 83.067  102.407 116.217 1.00 58.32  ?  343 ILE B CA  1 
ATOM   4478 C C   . ILE B 2 349 ? 83.098  100.959 115.751 1.00 58.32  ?  343 ILE B C   1 
ATOM   4479 O O   . ILE B 2 349 ? 83.258  100.688 114.554 1.00 58.32  ?  343 ILE B O   1 
ATOM   4480 C CB  . ILE B 2 349 ? 81.788  103.116 115.737 1.00 58.32  ?  343 ILE B CB  1 
ATOM   4481 C CG1 . ILE B 2 349 ? 81.831  104.599 116.119 1.00 58.32  ?  343 ILE B CG1 1 
ATOM   4482 C CG2 . ILE B 2 349 ? 80.553  102.447 116.331 1.00 58.32  ?  343 ILE B CG2 1 
ATOM   4483 C CD1 . ILE B 2 349 ? 80.632  105.396 115.645 1.00 58.32  ?  343 ILE B CD1 1 
ATOM   4484 N N   . TRP B 2 350 ? 82.951  100.033 116.695 1.00 60.70  ?  344 TRP B N   1 
ATOM   4485 C CA  . TRP B 2 350 ? 83.017  98.607  116.426 1.00 60.70  ?  344 TRP B CA  1 
ATOM   4486 C C   . TRP B 2 350 ? 81.674  97.959  116.732 1.00 60.70  ?  344 TRP B C   1 
ATOM   4487 O O   . TRP B 2 350 ? 80.921  98.424  117.594 1.00 60.70  ?  344 TRP B O   1 
ATOM   4488 C CB  . TRP B 2 350 ? 84.115  97.936  117.261 1.00 60.70  ?  344 TRP B CB  1 
ATOM   4489 C CG  . TRP B 2 350 ? 85.480  98.514  117.040 1.00 60.70  ?  344 TRP B CG  1 
ATOM   4490 C CD1 . TRP B 2 350 ? 85.953  99.704  117.514 1.00 60.70  ?  344 TRP B CD1 1 
ATOM   4491 C CD2 . TRP B 2 350 ? 86.553  97.924  116.296 1.00 60.70  ?  344 TRP B CD2 1 
ATOM   4492 N NE1 . TRP B 2 350 ? 87.251  99.892  117.108 1.00 60.70  ?  344 TRP B NE1 1 
ATOM   4493 C CE2 . TRP B 2 350 ? 87.644  98.814  116.359 1.00 60.70  ?  344 TRP B CE2 1 
ATOM   4494 C CE3 . TRP B 2 350 ? 86.696  96.731  115.581 1.00 60.70  ?  344 TRP B CE3 1 
ATOM   4495 C CZ2 . TRP B 2 350 ? 88.861  98.549  115.735 1.00 60.70  ?  344 TRP B CZ2 1 
ATOM   4496 C CZ3 . TRP B 2 350 ? 87.906  96.469  114.962 1.00 60.70  ?  344 TRP B CZ3 1 
ATOM   4497 C CH2 . TRP B 2 350 ? 88.972  97.374  115.044 1.00 60.70  ?  344 TRP B CH2 1 
ATOM   4498 N N   . ASN B 2 351 ? 81.384  96.877  116.016 1.00 61.33  ?  345 ASN B N   1 
ATOM   4499 C CA  . ASN B 2 351 ? 80.145  96.134  116.213 1.00 61.33  ?  345 ASN B CA  1 
ATOM   4500 C C   . ASN B 2 351 ? 80.306  94.688  115.757 1.00 61.33  ?  345 ASN B C   1 
ATOM   4501 O O   . ASN B 2 351 ? 81.147  94.383  114.911 1.00 61.33  ?  345 ASN B O   1 
ATOM   4502 C CB  . ASN B 2 351 ? 78.994  96.798  115.456 1.00 61.33  ?  345 ASN B CB  1 
ATOM   4503 C CG  . ASN B 2 351 ? 77.674  96.082  115.659 1.00 61.33  ?  345 ASN B CG  1 
ATOM   4504 O OD1 . ASN B 2 351 ? 77.505  95.326  116.615 1.00 61.33  ?  345 ASN B OD1 1 
ATOM   4505 N ND2 . ASN B 2 351 ? 76.728  96.318  114.757 1.00 61.33  ?  345 ASN B ND2 1 
ATOM   4506 N N   . VAL C 3 2   ? 66.188  136.384 118.564 1.00 64.97  ?  1   VAL E N   1 
ATOM   4507 C CA  . VAL C 3 2   ? 65.850  135.743 117.261 1.00 64.97  ?  1   VAL E CA  1 
ATOM   4508 C C   . VAL C 3 2   ? 64.814  136.583 116.522 1.00 64.97  ?  1   VAL E C   1 
ATOM   4509 O O   . VAL C 3 2   ? 63.673  136.713 116.965 1.00 64.97  ?  1   VAL E O   1 
ATOM   4510 C CB  . VAL C 3 2   ? 65.346  134.297 117.465 1.00 64.97  ?  1   VAL E CB  1 
ATOM   4511 C CG1 . VAL C 3 2   ? 64.147  134.264 118.408 1.00 64.97  ?  1   VAL E CG1 1 
ATOM   4512 C CG2 . VAL C 3 2   ? 65.001  133.658 116.127 1.00 64.97  ?  1   VAL E CG2 1 
ATOM   4513 N N   . GLN C 3 3   ? 65.219  137.158 115.391 1.00 66.18  ?  2   GLN E N   1 
ATOM   4514 C CA  . GLN C 3 3   ? 64.333  137.994 114.595 1.00 66.18  ?  2   GLN E CA  1 
ATOM   4515 C C   . GLN C 3 3   ? 64.741  137.913 113.132 1.00 66.18  ?  2   GLN E C   1 
ATOM   4516 O O   . GLN C 3 3   ? 65.932  137.859 112.812 1.00 66.18  ?  2   GLN E O   1 
ATOM   4517 C CB  . GLN C 3 3   ? 64.361  139.452 115.068 1.00 66.18  ?  2   GLN E CB  1 
ATOM   4518 C CG  . GLN C 3 3   ? 63.800  139.666 116.465 1.00 66.18  ?  2   GLN E CG  1 
ATOM   4519 C CD  . GLN C 3 3   ? 63.749  141.130 116.855 1.00 66.18  ?  2   GLN E CD  1 
ATOM   4520 O OE1 . GLN C 3 3   ? 64.209  141.998 116.113 1.00 66.18  ?  2   GLN E OE1 1 
ATOM   4521 N NE2 . GLN C 3 3   ? 63.187  141.412 118.024 1.00 66.18  ?  2   GLN E NE2 1 
ATOM   4522 N N   . LEU C 3 4   ? 63.740  137.907 112.253 1.00 64.88  ?  3   LEU E N   1 
ATOM   4523 C CA  . LEU C 3 4   ? 63.937  137.900 110.804 1.00 64.88  ?  3   LEU E CA  1 
ATOM   4524 C C   . LEU C 3 4   ? 63.039  138.987 110.220 1.00 64.88  ?  3   LEU E C   1 
ATOM   4525 O O   . LEU C 3 4   ? 61.842  138.763 110.014 1.00 64.88  ?  3   LEU E O   1 
ATOM   4526 C CB  . LEU C 3 4   ? 63.613  136.535 110.204 1.00 64.88  ?  3   LEU E CB  1 
ATOM   4527 C CG  . LEU C 3 4   ? 64.513  135.369 110.618 1.00 64.88  ?  3   LEU E CG  1 
ATOM   4528 C CD1 . LEU C 3 4   ? 63.986  134.062 110.048 1.00 64.88  ?  3   LEU E CD1 1 
ATOM   4529 C CD2 . LEU C 3 4   ? 65.942  135.612 110.166 1.00 64.88  ?  3   LEU E CD2 1 
ATOM   4530 N N   . VAL C 3 5   ? 63.610  140.158 109.957 1.00 66.66  ?  4   VAL E N   1 
ATOM   4531 C CA  . VAL C 3 5   ? 62.859  141.307 109.464 1.00 66.66  ?  4   VAL E CA  1 
ATOM   4532 C C   . VAL C 3 5   ? 63.043  141.386 107.955 1.00 66.66  ?  4   VAL E C   1 
ATOM   4533 O O   . VAL C 3 5   ? 64.157  141.612 107.468 1.00 66.66  ?  4   VAL E O   1 
ATOM   4534 C CB  . VAL C 3 5   ? 63.313  142.608 110.144 1.00 66.66  ?  4   VAL E CB  1 
ATOM   4535 C CG1 . VAL C 3 5   ? 62.470  143.782 109.667 1.00 66.66  ?  4   VAL E CG1 1 
ATOM   4536 C CG2 . VAL C 3 5   ? 63.238  142.470 111.659 1.00 66.66  ?  4   VAL E CG2 1 
ATOM   4537 N N   . GLU C 3 6   ? 61.955  141.202 107.215 1.00 67.48  ?  5   GLU E N   1 
ATOM   4538 C CA  . GLU C 3 6   ? 61.973  141.266 105.761 1.00 67.48  ?  5   GLU E CA  1 
ATOM   4539 C C   . GLU C 3 6   ? 61.530  142.645 105.286 1.00 67.48  ?  5   GLU E C   1 
ATOM   4540 O O   . GLU C 3 6   ? 60.800  143.363 105.974 1.00 67.48  ?  5   GLU E O   1 
ATOM   4541 C CB  . GLU C 3 6   ? 61.068  140.189 105.155 1.00 67.48  ?  5   GLU E CB  1 
ATOM   4542 C CG  . GLU C 3 6   ? 61.551  138.761 105.378 1.00 67.48  ?  5   GLU E CG  1 
ATOM   4543 C CD  . GLU C 3 6   ? 61.418  138.313 106.820 1.00 67.48  ?  5   GLU E CD  1 
ATOM   4544 O OE1 . GLU C 3 6   ? 60.817  139.058 107.622 1.00 67.48  ?  5   GLU E OE1 1 
ATOM   4545 O OE2 . GLU C 3 6   ? 61.914  137.216 107.151 1.00 67.48  ?  5   GLU E OE2 1 
ATOM   4546 N N   . SER C 3 7   ? 61.984  143.007 104.089 1.00 68.20  ?  6   SER E N   1 
ATOM   4547 C CA  . SER C 3 7   ? 61.644  144.295 103.502 1.00 68.20  ?  6   SER E CA  1 
ATOM   4548 C C   . SER C 3 7   ? 61.946  144.245 102.011 1.00 68.20  ?  6   SER E C   1 
ATOM   4549 O O   . SER C 3 7   ? 62.567  143.304 101.511 1.00 68.20  ?  6   SER E O   1 
ATOM   4550 C CB  . SER C 3 7   ? 62.410  145.437 104.179 1.00 68.20  ?  6   SER E CB  1 
ATOM   4551 O OG  . SER C 3 7   ? 62.073  146.687 103.605 1.00 68.20  ?  6   SER E OG  1 
ATOM   4552 N N   . GLY C 3 8   ? 61.500  145.283 101.306 1.00 69.09  ?  7   GLY E N   1 
ATOM   4553 C CA  . GLY C 3 8   ? 61.685  145.397 99.873  1.00 69.09  ?  7   GLY E CA  1 
ATOM   4554 C C   . GLY C 3 8   ? 60.417  145.227 99.066  1.00 69.09  ?  7   GLY E C   1 
ATOM   4555 O O   . GLY C 3 8   ? 60.428  145.515 97.862  1.00 69.09  ?  7   GLY E O   1 
ATOM   4556 N N   . GLY C 3 9   ? 59.330  144.774 99.680  1.00 69.48  ?  8   GLY E N   1 
ATOM   4557 C CA  . GLY C 3 9   ? 58.082  144.592 98.973  1.00 69.48  ?  8   GLY E CA  1 
ATOM   4558 C C   . GLY C 3 9   ? 57.499  145.908 98.492  1.00 69.48  ?  8   GLY E C   1 
ATOM   4559 O O   . GLY C 3 9   ? 58.044  146.993 98.699  1.00 69.48  ?  8   GLY E O   1 
ATOM   4560 N N   . GLY C 3 10  ? 56.354  145.798 97.832  1.00 70.99  ?  9   GLY E N   1 
ATOM   4561 C CA  . GLY C 3 10  ? 55.657  146.939 97.285  1.00 70.99  ?  9   GLY E CA  1 
ATOM   4562 C C   . GLY C 3 10  ? 55.061  146.598 95.938  1.00 70.99  ?  9   GLY E C   1 
ATOM   4563 O O   . GLY C 3 10  ? 54.918  145.430 95.584  1.00 70.99  ?  9   GLY E O   1 
ATOM   4564 N N   . LEU C 3 11  ? 54.712  147.638 95.186  1.00 72.38  ?  10  LEU E N   1 
ATOM   4565 C CA  . LEU C 3 11  ? 54.110  147.476 93.870  1.00 72.38  ?  10  LEU E CA  1 
ATOM   4566 C C   . LEU C 3 11  ? 55.188  147.469 92.794  1.00 72.38  ?  10  LEU E C   1 
ATOM   4567 O O   . LEU C 3 11  ? 56.108  148.291 92.814  1.00 72.38  ?  10  LEU E O   1 
ATOM   4568 C CB  . LEU C 3 11  ? 53.110  148.600 93.595  1.00 72.38  ?  10  LEU E CB  1 
ATOM   4569 C CG  . LEU C 3 11  ? 52.033  148.820 94.660  1.00 72.38  ?  10  LEU E CG  1 
ATOM   4570 C CD1 . LEU C 3 11  ? 51.105  149.954 94.253  1.00 72.38  ?  10  LEU E CD1 1 
ATOM   4571 C CD2 . LEU C 3 11  ? 51.245  147.543 94.908  1.00 72.38  ?  10  LEU E CD2 1 
ATOM   4572 N N   . VAL C 3 12  ? 55.069  146.532 91.855  1.00 72.10  ?  11  VAL E N   1 
ATOM   4573 C CA  . VAL C 3 12  ? 56.003  146.416 90.740  1.00 72.10  ?  11  VAL E CA  1 
ATOM   4574 C C   . VAL C 3 12  ? 55.205  146.179 89.466  1.00 72.10  ?  11  VAL E C   1 
ATOM   4575 O O   . VAL C 3 12  ? 54.196  145.466 89.475  1.00 72.10  ?  11  VAL E O   1 
ATOM   4576 C CB  . VAL C 3 12  ? 57.023  145.278 90.959  1.00 72.10  ?  11  VAL E CB  1 
ATOM   4577 C CG1 . VAL C 3 12  ? 57.953  145.160 89.760  1.00 72.10  ?  11  VAL E CG1 1 
ATOM   4578 C CG2 . VAL C 3 12  ? 57.824  145.511 92.232  1.00 72.10  ?  11  VAL E CG2 1 
ATOM   4579 N N   . GLN C 3 13  ? 55.654  146.782 88.371  1.00 72.95  ?  12  GLN E N   1 
ATOM   4580 C CA  . GLN C 3 13  ? 55.002  146.598 87.087  1.00 72.95  ?  12  GLN E CA  1 
ATOM   4581 C C   . GLN C 3 13  ? 55.461  145.295 86.438  1.00 72.95  ?  12  GLN E C   1 
ATOM   4582 O O   . GLN C 3 13  ? 56.510  144.750 86.790  1.00 72.95  ?  12  GLN E O   1 
ATOM   4583 C CB  . GLN C 3 13  ? 55.304  147.776 86.166  1.00 72.95  ?  12  GLN E CB  1 
ATOM   4584 C CG  . GLN C 3 13  ? 54.564  149.059 86.523  1.00 72.95  ?  12  GLN E CG  1 
ATOM   4585 C CD  . GLN C 3 13  ? 54.987  149.630 87.863  1.00 72.95  ?  12  GLN E CD  1 
ATOM   4586 O OE1 . GLN C 3 13  ? 55.893  149.110 88.515  1.00 72.95  ?  12  GLN E OE1 1 
ATOM   4587 N NE2 . GLN C 3 13  ? 54.331  150.707 88.281  1.00 72.95  ?  12  GLN E NE2 1 
ATOM   4588 N N   . PRO C 3 14  ? 54.687  144.770 85.488  1.00 74.06  ?  13  PRO E N   1 
ATOM   4589 C CA  . PRO C 3 14  ? 55.092  143.525 84.823  1.00 74.06  ?  13  PRO E CA  1 
ATOM   4590 C C   . PRO C 3 14  ? 56.447  143.669 84.147  1.00 74.06  ?  13  PRO E C   1 
ATOM   4591 O O   . PRO C 3 14  ? 56.753  144.695 83.536  1.00 74.06  ?  13  PRO E O   1 
ATOM   4592 C CB  . PRO C 3 14  ? 53.974  143.286 83.802  1.00 74.06  ?  13  PRO E CB  1 
ATOM   4593 C CG  . PRO C 3 14  ? 52.806  144.048 84.323  1.00 74.06  ?  13  PRO E CG  1 
ATOM   4594 C CD  . PRO C 3 14  ? 53.377  145.248 85.012  1.00 74.06  ?  13  PRO E CD  1 
ATOM   4595 N N   . GLY C 3 15  ? 57.263  142.622 84.265  1.00 73.75  ?  14  GLY E N   1 
ATOM   4596 C CA  . GLY C 3 15  ? 58.579  142.603 83.664  1.00 73.75  ?  14  GLY E CA  1 
ATOM   4597 C C   . GLY C 3 15  ? 59.666  143.276 84.471  1.00 73.75  ?  14  GLY E C   1 
ATOM   4598 O O   . GLY C 3 15  ? 60.839  143.197 84.083  1.00 73.75  ?  14  GLY E O   1 
ATOM   4599 N N   . GLY C 3 16  ? 59.328  143.933 85.577  1.00 72.69  ?  15  GLY E N   1 
ATOM   4600 C CA  . GLY C 3 16  ? 60.309  144.609 86.395  1.00 72.69  ?  15  GLY E CA  1 
ATOM   4601 C C   . GLY C 3 16  ? 61.110  143.642 87.246  1.00 72.69  ?  15  GLY E C   1 
ATOM   4602 O O   . GLY C 3 16  ? 61.030  142.420 87.113  1.00 72.69  ?  15  GLY E O   1 
ATOM   4603 N N   . SER C 3 17  ? 61.906  144.220 88.145  1.00 72.45  ?  16  SER E N   1 
ATOM   4604 C CA  . SER C 3 17  ? 62.750  143.452 89.048  1.00 72.45  ?  16  SER E CA  1 
ATOM   4605 C C   . SER C 3 17  ? 62.643  144.043 90.447  1.00 72.45  ?  16  SER E C   1 
ATOM   4606 O O   . SER C 3 17  ? 62.126  145.147 90.641  1.00 72.45  ?  16  SER E O   1 
ATOM   4607 C CB  . SER C 3 17  ? 64.210  143.442 88.577  1.00 72.45  ?  16  SER E CB  1 
ATOM   4608 O OG  . SER C 3 17  ? 64.322  142.888 87.278  1.00 72.45  ?  16  SER E OG  1 
ATOM   4609 N N   . ARG C 3 18  ? 63.141  143.297 91.432  1.00 70.59  ?  17  ARG E N   1 
ATOM   4610 C CA  . ARG C 3 18  ? 63.098  143.764 92.811  1.00 70.59  ?  17  ARG E CA  1 
ATOM   4611 C C   . ARG C 3 18  ? 63.997  142.887 93.670  1.00 70.59  ?  17  ARG E C   1 
ATOM   4612 O O   . ARG C 3 18  ? 64.049  141.670 93.478  1.00 70.59  ?  17  ARG E O   1 
ATOM   4613 C CB  . ARG C 3 18  ? 61.662  143.748 93.356  1.00 70.59  ?  17  ARG E CB  1 
ATOM   4614 C CG  . ARG C 3 18  ? 61.529  144.211 94.803  1.00 70.59  ?  17  ARG E CG  1 
ATOM   4615 C CD  . ARG C 3 18  ? 62.038  145.633 94.998  1.00 70.59  ?  17  ARG E CD  1 
ATOM   4616 N NE  . ARG C 3 18  ? 61.353  146.590 94.132  1.00 70.59  ?  17  ARG E NE  1 
ATOM   4617 C CZ  . ARG C 3 18  ? 60.197  147.181 94.424  1.00 70.59  ?  17  ARG E CZ  1 
ATOM   4618 N NH1 . ARG C 3 18  ? 59.575  146.918 95.566  1.00 70.59  1  17  ARG E NH1 1 
ATOM   4619 N NH2 . ARG C 3 18  ? 59.659  148.037 93.567  1.00 70.59  ?  17  ARG E NH2 1 
ATOM   4620 N N   . LYS C 3 19  ? 64.691  143.511 94.618  1.00 69.35  ?  18  LYS E N   1 
ATOM   4621 C CA  . LYS C 3 19  ? 65.594  142.820 95.536  1.00 69.35  ?  18  LYS E CA  1 
ATOM   4622 C C   . LYS C 3 19  ? 64.967  142.837 96.926  1.00 69.35  ?  18  LYS E C   1 
ATOM   4623 O O   . LYS C 3 19  ? 65.024  143.850 97.630  1.00 69.35  ?  18  LYS E O   1 
ATOM   4624 C CB  . LYS C 3 19  ? 66.971  143.477 95.541  1.00 69.35  ?  18  LYS E CB  1 
ATOM   4625 C CG  . LYS C 3 19  ? 67.991  142.765 96.420  1.00 69.35  ?  18  LYS E CG  1 
ATOM   4626 C CD  . LYS C 3 19  ? 69.358  143.433 96.361  1.00 69.35  ?  18  LYS E CD  1 
ATOM   4627 C CE  . LYS C 3 19  ? 69.341  144.814 97.000  1.00 69.35  ?  18  LYS E CE  1 
ATOM   4628 N NZ  . LYS C 3 19  ? 70.696  145.428 97.037  1.00 69.35  1  18  LYS E NZ  1 
ATOM   4629 N N   . LEU C 3 20  ? 64.369  141.715 97.320  1.00 68.90  ?  19  LEU E N   1 
ATOM   4630 C CA  . LEU C 3 20  ? 63.799  141.581 98.655  1.00 68.90  ?  19  LEU E CA  1 
ATOM   4631 C C   . LEU C 3 20  ? 64.908  141.229 99.640  1.00 68.90  ?  19  LEU E C   1 
ATOM   4632 O O   . LEU C 3 20  ? 65.631  140.246 99.443  1.00 68.90  ?  19  LEU E O   1 
ATOM   4633 C CB  . LEU C 3 20  ? 62.709  140.512 98.666  1.00 68.90  ?  19  LEU E CB  1 
ATOM   4634 C CG  . LEU C 3 20  ? 61.545  140.722 97.694  1.00 68.90  ?  19  LEU E CG  1 
ATOM   4635 C CD1 . LEU C 3 20  ? 60.544  139.584 97.812  1.00 68.90  ?  19  LEU E CD1 1 
ATOM   4636 C CD2 . LEU C 3 20  ? 60.866  142.061 97.937  1.00 68.90  ?  19  LEU E CD2 1 
ATOM   4637 N N   . SER C 3 21  ? 65.042  142.027 100.695 1.00 67.89  ?  20  SER E N   1 
ATOM   4638 C CA  . SER C 3 21  ? 66.086  141.845 101.692 1.00 67.89  ?  20  SER E CA  1 
ATOM   4639 C C   . SER C 3 21  ? 65.490  141.294 102.981 1.00 67.89  ?  20  SER E C   1 
ATOM   4640 O O   . SER C 3 21  ? 64.302  141.474 103.265 1.00 67.89  ?  20  SER E O   1 
ATOM   4641 C CB  . SER C 3 21  ? 66.807  143.166 101.977 1.00 67.89  ?  20  SER E CB  1 
ATOM   4642 O OG  . SER C 3 21  ? 67.842  142.989 102.930 1.00 67.89  ?  20  SER E OG  1 
ATOM   4643 N N   . CYS C 3 22  ? 66.331  140.615 103.759 1.00 66.52  ?  21  CYS E N   1 
ATOM   4644 C CA  . CYS C 3 22  ? 65.921  140.036 105.033 1.00 66.52  ?  21  CYS E CA  1 
ATOM   4645 C C   . CYS C 3 22  ? 67.089  140.116 106.002 1.00 66.52  ?  21  CYS E C   1 
ATOM   4646 O O   . CYS C 3 22  ? 68.126  139.483 105.780 1.00 66.52  ?  21  CYS E O   1 
ATOM   4647 C CB  . CYS C 3 22  ? 65.464  138.584 104.861 1.00 66.52  ?  21  CYS E CB  1 
ATOM   4648 S SG  . CYS C 3 22  ? 64.973  137.775 106.401 1.00 66.52  ?  21  CYS E SG  1 
ATOM   4649 N N   . SER C 3 23  ? 66.920  140.895 107.066 1.00 66.08  ?  22  SER E N   1 
ATOM   4650 C CA  . SER C 3 23  ? 67.928  141.021 108.109 1.00 66.08  ?  22  SER E CA  1 
ATOM   4651 C C   . SER C 3 23  ? 67.631  140.030 109.227 1.00 66.08  ?  22  SER E C   1 
ATOM   4652 O O   . SER C 3 23  ? 66.516  139.999 109.760 1.00 66.08  ?  22  SER E O   1 
ATOM   4653 C CB  . SER C 3 23  ? 67.961  142.447 108.659 1.00 66.08  ?  22  SER E CB  1 
ATOM   4654 O OG  . SER C 3 23  ? 66.710  142.807 109.218 1.00 66.08  ?  22  SER E OG  1 
ATOM   4655 N N   . ALA C 3 24  ? 68.629  139.225 109.576 1.00 65.18  ?  23  ALA E N   1 
ATOM   4656 C CA  . ALA C 3 24  ? 68.511  138.222 110.624 1.00 65.18  ?  23  ALA E CA  1 
ATOM   4657 C C   . ALA C 3 24  ? 69.323  138.648 111.839 1.00 65.18  ?  23  ALA E C   1 
ATOM   4658 O O   . ALA C 3 24  ? 70.406  139.227 111.703 1.00 65.18  ?  23  ALA E O   1 
ATOM   4659 C CB  . ALA C 3 24  ? 68.991  136.855 110.131 1.00 65.18  ?  23  ALA E CB  1 
ATOM   4660 N N   . SER C 3 25  ? 68.794  138.361 113.026 1.00 65.12  ?  24  SER E N   1 
ATOM   4661 C CA  . SER C 3 25  ? 69.475  138.709 114.263 1.00 65.12  ?  24  SER E CA  1 
ATOM   4662 C C   . SER C 3 25  ? 69.093  137.708 115.342 1.00 65.12  ?  24  SER E C   1 
ATOM   4663 O O   . SER C 3 25  ? 68.106  136.978 115.220 1.00 65.12  ?  24  SER E O   1 
ATOM   4664 C CB  . SER C 3 25  ? 69.132  140.136 114.712 1.00 65.12  ?  24  SER E CB  1 
ATOM   4665 O OG  . SER C 3 25  ? 67.738  140.284 114.921 1.00 65.12  ?  24  SER E OG  1 
ATOM   4666 N N   . GLY C 3 26  ? 69.896  137.680 116.404 1.00 64.16  ?  25  GLY E N   1 
ATOM   4667 C CA  . GLY C 3 26  ? 69.630  136.814 117.533 1.00 64.16  ?  25  GLY E CA  1 
ATOM   4668 C C   . GLY C 3 26  ? 70.110  135.389 117.382 1.00 64.16  ?  25  GLY E C   1 
ATOM   4669 O O   . GLY C 3 26  ? 69.734  134.540 118.198 1.00 64.16  ?  25  GLY E O   1 
ATOM   4670 N N   . PHE C 3 27  ? 70.922  135.094 116.372 1.00 63.36  ?  26  PHE E N   1 
ATOM   4671 C CA  . PHE C 3 27  ? 71.430  133.744 116.164 1.00 63.36  ?  26  PHE E CA  1 
ATOM   4672 C C   . PHE C 3 27  ? 72.490  133.795 115.073 1.00 63.36  ?  26  PHE E C   1 
ATOM   4673 O O   . PHE C 3 27  ? 72.687  134.822 114.417 1.00 63.36  ?  26  PHE E O   1 
ATOM   4674 C CB  . PHE C 3 27  ? 70.308  132.772 115.789 1.00 63.36  ?  26  PHE E CB  1 
ATOM   4675 C CG  . PHE C 3 27  ? 69.624  133.106 114.495 1.00 63.36  ?  26  PHE E CG  1 
ATOM   4676 C CD1 . PHE C 3 27  ? 68.563  133.996 114.467 1.00 63.36  ?  26  PHE E CD1 1 
ATOM   4677 C CD2 . PHE C 3 27  ? 70.039  132.527 113.308 1.00 63.36  ?  26  PHE E CD2 1 
ATOM   4678 C CE1 . PHE C 3 27  ? 67.932  134.304 113.277 1.00 63.36  ?  26  PHE E CE1 1 
ATOM   4679 C CE2 . PHE C 3 27  ? 69.411  132.832 112.116 1.00 63.36  ?  26  PHE E CE2 1 
ATOM   4680 C CZ  . PHE C 3 27  ? 68.357  133.721 112.101 1.00 63.36  ?  26  PHE E CZ  1 
ATOM   4681 N N   . ALA C 3 28  ? 73.174  132.668 114.889 1.00 62.74  ?  27  ALA E N   1 
ATOM   4682 C CA  . ALA C 3 28  ? 74.202  132.539 113.859 1.00 62.74  ?  27  ALA E CA  1 
ATOM   4683 C C   . ALA C 3 28  ? 73.512  132.363 112.512 1.00 62.74  ?  27  ALA E C   1 
ATOM   4684 O O   . ALA C 3 28  ? 73.018  131.280 112.189 1.00 62.74  ?  27  ALA E O   1 
ATOM   4685 C CB  . ALA C 3 28  ? 75.128  131.369 114.167 1.00 62.74  ?  27  ALA E CB  1 
ATOM   4686 N N   . PHE C 3 29  ? 73.479  133.435 111.719 1.00 64.72  ?  28  PHE E N   1 
ATOM   4687 C CA  . PHE C 3 29  ? 72.800  133.377 110.428 1.00 64.72  ?  28  PHE E CA  1 
ATOM   4688 C C   . PHE C 3 29  ? 73.460  132.364 109.500 1.00 64.72  ?  28  PHE E C   1 
ATOM   4689 O O   . PHE C 3 29  ? 72.773  131.654 108.756 1.00 64.72  ?  28  PHE E O   1 
ATOM   4690 C CB  . PHE C 3 29  ? 72.787  134.765 109.786 1.00 64.72  ?  28  PHE E CB  1 
ATOM   4691 C CG  . PHE C 3 29  ? 72.216  134.784 108.397 1.00 64.72  ?  28  PHE E CG  1 
ATOM   4692 C CD1 . PHE C 3 29  ? 70.847  134.823 108.196 1.00 64.72  ?  28  PHE E CD1 1 
ATOM   4693 C CD2 . PHE C 3 29  ? 73.050  134.769 107.292 1.00 64.72  ?  28  PHE E CD2 1 
ATOM   4694 C CE1 . PHE C 3 29  ? 70.320  134.842 106.919 1.00 64.72  ?  28  PHE E CE1 1 
ATOM   4695 C CE2 . PHE C 3 29  ? 72.530  134.788 106.014 1.00 64.72  ?  28  PHE E CE2 1 
ATOM   4696 C CZ  . PHE C 3 29  ? 71.163  134.825 105.827 1.00 64.72  ?  28  PHE E CZ  1 
ATOM   4697 N N   . SER C 3 30  ? 74.792  132.283 109.527 1.00 63.29  ?  29  SER E N   1 
ATOM   4698 C CA  . SER C 3 30  ? 75.492  131.361 108.640 1.00 63.29  ?  29  SER E CA  1 
ATOM   4699 C C   . SER C 3 30  ? 75.210  129.907 108.998 1.00 63.29  ?  29  SER E C   1 
ATOM   4700 O O   . SER C 3 30  ? 75.210  129.042 108.115 1.00 63.29  ?  29  SER E O   1 
ATOM   4701 C CB  . SER C 3 30  ? 76.995  131.632 108.684 1.00 63.29  ?  29  SER E CB  1 
ATOM   4702 O OG  . SER C 3 30  ? 77.698  130.746 107.830 1.00 63.29  ?  29  SER E OG  1 
ATOM   4703 N N   . SER C 3 31  ? 74.970  129.617 110.279 1.00 62.18  ?  30  SER E N   1 
ATOM   4704 C CA  . SER C 3 31  ? 74.746  128.240 110.703 1.00 62.18  ?  30  SER E CA  1 
ATOM   4705 C C   . SER C 3 31  ? 73.397  127.699 110.248 1.00 62.18  ?  30  SER E C   1 
ATOM   4706 O O   . SER C 3 31  ? 73.215  126.477 110.218 1.00 62.18  ?  30  SER E O   1 
ATOM   4707 C CB  . SER C 3 31  ? 74.854  128.138 112.225 1.00 62.18  ?  30  SER E CB  1 
ATOM   4708 O OG  . SER C 3 31  ? 76.135  128.542 112.674 1.00 62.18  ?  30  SER E OG  1 
ATOM   4709 N N   . PHE C 3 32  ? 72.455  128.569 109.896 1.00 62.23  ?  31  PHE E N   1 
ATOM   4710 C CA  . PHE C 3 32  ? 71.112  128.167 109.499 1.00 62.23  ?  31  PHE E CA  1 
ATOM   4711 C C   . PHE C 3 32  ? 70.925  128.389 108.005 1.00 62.23  ?  31  PHE E C   1 
ATOM   4712 O O   . PHE C 3 32  ? 71.210  129.477 107.494 1.00 62.23  ?  31  PHE E O   1 
ATOM   4713 C CB  . PHE C 3 32  ? 70.053  128.953 110.275 1.00 62.23  ?  31  PHE E CB  1 
ATOM   4714 C CG  . PHE C 3 32  ? 69.931  128.551 111.716 1.00 62.23  ?  31  PHE E CG  1 
ATOM   4715 C CD1 . PHE C 3 32  ? 68.980  127.625 112.111 1.00 62.23  ?  31  PHE E CD1 1 
ATOM   4716 C CD2 . PHE C 3 32  ? 70.764  129.099 112.676 1.00 62.23  ?  31  PHE E CD2 1 
ATOM   4717 C CE1 . PHE C 3 32  ? 68.863  127.253 113.436 1.00 62.23  ?  31  PHE E CE1 1 
ATOM   4718 C CE2 . PHE C 3 32  ? 70.652  128.731 114.002 1.00 62.23  ?  31  PHE E CE2 1 
ATOM   4719 C CZ  . PHE C 3 32  ? 69.700  127.807 114.383 1.00 62.23  ?  31  PHE E CZ  1 
ATOM   4720 N N   . GLY C 3 33  ? 70.446  127.358 107.312 1.00 63.51  ?  32  GLY E N   1 
ATOM   4721 C CA  . GLY C 3 33  ? 70.055  127.528 105.928 1.00 63.51  ?  32  GLY E CA  1 
ATOM   4722 C C   . GLY C 3 33  ? 68.760  128.309 105.812 1.00 63.51  ?  32  GLY E C   1 
ATOM   4723 O O   . GLY C 3 33  ? 67.884  128.242 106.674 1.00 63.51  ?  32  GLY E O   1 
ATOM   4724 N N   . MET C 3 34  ? 68.639  129.064 104.724 1.00 64.61  ?  33  MET E N   1 
ATOM   4725 C CA  . MET C 3 34  ? 67.522  129.978 104.533 1.00 64.61  ?  33  MET E CA  1 
ATOM   4726 C C   . MET C 3 34  ? 66.585  129.449 103.456 1.00 64.61  ?  33  MET E C   1 
ATOM   4727 O O   . MET C 3 34  ? 67.026  128.843 102.475 1.00 64.61  ?  33  MET E O   1 
ATOM   4728 C CB  . MET C 3 34  ? 68.017  131.375 104.153 1.00 64.61  ?  33  MET E CB  1 
ATOM   4729 C CG  . MET C 3 34  ? 69.201  131.858 104.978 1.00 64.61  ?  33  MET E CG  1 
ATOM   4730 S SD  . MET C 3 34  ? 68.958  131.658 106.755 1.00 64.61  ?  33  MET E SD  1 
ATOM   4731 C CE  . MET C 3 34  ? 67.491  132.650 107.016 1.00 64.61  ?  33  MET E CE  1 
ATOM   4732 N N   . HIS C 3 35  ? 65.288  129.676 103.655 1.00 63.81  ?  34  HIS E N   1 
ATOM   4733 C CA  . HIS C 3 35  ? 64.256  129.266 102.709 1.00 63.81  ?  34  HIS E CA  1 
ATOM   4734 C C   . HIS C 3 35  ? 63.333  130.446 102.452 1.00 63.81  ?  34  HIS E C   1 
ATOM   4735 O O   . HIS C 3 35  ? 62.760  131.003 103.394 1.00 63.81  ?  34  HIS E O   1 
ATOM   4736 C CB  . HIS C 3 35  ? 63.452  128.076 103.242 1.00 63.81  ?  34  HIS E CB  1 
ATOM   4737 C CG  . HIS C 3 35  ? 64.278  126.861 103.527 1.00 63.81  ?  34  HIS E CG  1 
ATOM   4738 N ND1 . HIS C 3 35  ? 65.219  126.818 104.533 1.00 63.81  ?  34  HIS E ND1 1 
ATOM   4739 C CD2 . HIS C 3 35  ? 64.298  125.639 102.942 1.00 63.81  ?  34  HIS E CD2 1 
ATOM   4740 C CE1 . HIS C 3 35  ? 65.785  125.625 104.553 1.00 63.81  ?  34  HIS E CE1 1 
ATOM   4741 N NE2 . HIS C 3 35  ? 65.244  124.890 103.599 1.00 63.81  ?  34  HIS E NE2 1 
ATOM   4742 N N   . TRP C 3 36  ? 63.197  130.829 101.186 1.00 65.80  ?  35  TRP E N   1 
ATOM   4743 C CA  . TRP C 3 36  ? 62.217  131.820 100.762 1.00 65.80  ?  35  TRP E CA  1 
ATOM   4744 C C   . TRP C 3 36  ? 60.969  131.086 100.290 1.00 65.80  ?  35  TRP E C   1 
ATOM   4745 O O   . TRP C 3 36  ? 61.039  130.278 99.355  1.00 65.80  ?  35  TRP E O   1 
ATOM   4746 C CB  . TRP C 3 36  ? 62.770  132.709 99.648  1.00 65.80  ?  35  TRP E CB  1 
ATOM   4747 C CG  . TRP C 3 36  ? 63.506  133.916 100.142 1.00 65.80  ?  35  TRP E CG  1 
ATOM   4748 C CD1 . TRP C 3 36  ? 64.848  134.145 100.069 1.00 65.80  ?  35  TRP E CD1 1 
ATOM   4749 C CD2 . TRP C 3 36  ? 62.937  135.063 100.786 1.00 65.80  ?  35  TRP E CD2 1 
ATOM   4750 N NE1 . TRP C 3 36  ? 65.151  135.364 100.625 1.00 65.80  ?  35  TRP E NE1 1 
ATOM   4751 C CE2 . TRP C 3 36  ? 63.996  135.947 101.074 1.00 65.80  ?  35  TRP E CE2 1 
ATOM   4752 C CE3 . TRP C 3 36  ? 61.637  135.428 101.147 1.00 65.80  ?  35  TRP E CE3 1 
ATOM   4753 C CZ2 . TRP C 3 36  ? 63.794  137.172 101.706 1.00 65.80  ?  35  TRP E CZ2 1 
ATOM   4754 C CZ3 . TRP C 3 36  ? 61.438  136.645 101.774 1.00 65.80  ?  35  TRP E CZ3 1 
ATOM   4755 C CH2 . TRP C 3 36  ? 62.511  137.502 102.047 1.00 65.80  ?  35  TRP E CH2 1 
ATOM   4756 N N   . VAL C 3 37  ? 59.838  131.369 100.937 1.00 65.85  ?  36  VAL E N   1 
ATOM   4757 C CA  . VAL C 3 37  ? 58.571  130.701 100.662 1.00 65.85  ?  36  VAL E CA  1 
ATOM   4758 C C   . VAL C 3 37  ? 57.514  131.763 100.395 1.00 65.85  ?  36  VAL E C   1 
ATOM   4759 O O   . VAL C 3 37  ? 57.381  132.719 101.165 1.00 65.85  ?  36  VAL E O   1 
ATOM   4760 C CB  . VAL C 3 37  ? 58.141  129.795 101.833 1.00 65.85  ?  36  VAL E CB  1 
ATOM   4761 C CG1 . VAL C 3 37  ? 56.717  129.295 101.629 1.00 65.85  ?  36  VAL E CG1 1 
ATOM   4762 C CG2 . VAL C 3 37  ? 59.115  128.632 101.989 1.00 65.85  ?  36  VAL E CG2 1 
ATOM   4763 N N   . ARG C 3 38  ? 56.758  131.592 99.314  1.00 68.03  ?  37  ARG E N   1 
ATOM   4764 C CA  . ARG C 3 38  ? 55.742  132.554 98.916  1.00 68.03  ?  37  ARG E CA  1 
ATOM   4765 C C   . ARG C 3 38  ? 54.355  132.065 99.314  1.00 68.03  ?  37  ARG E C   1 
ATOM   4766 O O   . ARG C 3 38  ? 54.096  130.861 99.391  1.00 68.03  ?  37  ARG E O   1 
ATOM   4767 C CB  . ARG C 3 38  ? 55.786  132.804 97.407  1.00 68.03  ?  37  ARG E CB  1 
ATOM   4768 C CG  . ARG C 3 38  ? 55.139  131.707 96.574  1.00 68.03  ?  37  ARG E CG  1 
ATOM   4769 C CD  . ARG C 3 38  ? 55.589  131.762 95.122  1.00 68.03  ?  37  ARG E CD  1 
ATOM   4770 N NE  . ARG C 3 38  ? 55.617  133.125 94.601  1.00 68.03  ?  37  ARG E NE  1 
ATOM   4771 C CZ  . ARG C 3 38  ? 56.061  133.453 93.392  1.00 68.03  ?  37  ARG E CZ  1 
ATOM   4772 N NH1 . ARG C 3 38  ? 56.518  132.518 92.569  1.00 68.03  1  37  ARG E NH1 1 
ATOM   4773 N NH2 . ARG C 3 38  ? 56.050  134.721 93.004  1.00 68.03  ?  37  ARG E NH2 1 
ATOM   4774 N N   . GLN C 3 39  ? 53.462  133.020 99.568  1.00 69.04  ?  38  GLN E N   1 
ATOM   4775 C CA  . GLN C 3 39  ? 52.070  132.742 99.895  1.00 69.04  ?  38  GLN E CA  1 
ATOM   4776 C C   . GLN C 3 39  ? 51.198  133.696 99.095  1.00 69.04  ?  38  GLN E C   1 
ATOM   4777 O O   . GLN C 3 39  ? 51.275  134.915 99.285  1.00 69.04  ?  38  GLN E O   1 
ATOM   4778 C CB  . GLN C 3 39  ? 51.811  132.903 101.396 1.00 69.04  ?  38  GLN E CB  1 
ATOM   4779 C CG  . GLN C 3 39  ? 50.386  132.580 101.822 1.00 69.04  ?  38  GLN E CG  1 
ATOM   4780 C CD  . GLN C 3 39  ? 50.169  132.761 103.312 1.00 69.04  ?  38  GLN E CD  1 
ATOM   4781 O OE1 . GLN C 3 39  ? 51.079  133.155 104.040 1.00 69.04  ?  38  GLN E OE1 1 
ATOM   4782 N NE2 . GLN C 3 39  ? 48.957  132.473 103.772 1.00 69.04  ?  38  GLN E NE2 1 
ATOM   4783 N N   . ALA C 3 40  ? 50.387  133.146 98.195  1.00 70.86  ?  39  ALA E N   1 
ATOM   4784 C CA  . ALA C 3 40  ? 49.520  133.964 97.370  1.00 70.86  ?  39  ALA E CA  1 
ATOM   4785 C C   . ALA C 3 40  ? 48.335  134.473 98.188  1.00 70.86  ?  39  ALA E C   1 
ATOM   4786 O O   . ALA C 3 40  ? 47.949  133.862 99.187  1.00 70.86  ?  39  ALA E O   1 
ATOM   4787 C CB  . ALA C 3 40  ? 49.028  133.166 96.166  1.00 70.86  ?  39  ALA E CB  1 
ATOM   4788 N N   . PRO C 3 41  ? 47.740  135.594 97.784  1.00 71.95  ?  40  PRO E N   1 
ATOM   4789 C CA  . PRO C 3 41  ? 46.603  136.132 98.541  1.00 71.95  ?  40  PRO E CA  1 
ATOM   4790 C C   . PRO C 3 41  ? 45.422  135.172 98.524  1.00 71.95  ?  40  PRO E C   1 
ATOM   4791 O O   . PRO C 3 41  ? 45.029  134.661 97.473  1.00 71.95  ?  40  PRO E O   1 
ATOM   4792 C CB  . PRO C 3 41  ? 46.282  137.446 97.817  1.00 71.95  ?  40  PRO E CB  1 
ATOM   4793 C CG  . PRO C 3 41  ? 46.846  137.279 96.449  1.00 71.95  ?  40  PRO E CG  1 
ATOM   4794 C CD  . PRO C 3 41  ? 48.066  136.427 96.613  1.00 71.95  ?  40  PRO E CD  1 
ATOM   4795 N N   . GLU C 3 42  ? 44.860  134.927 99.708  1.00 75.63  ?  41  GLU E N   1 
ATOM   4796 C CA  . GLU C 3 42  ? 43.718  134.028 99.867  1.00 75.63  ?  41  GLU E CA  1 
ATOM   4797 C C   . GLU C 3 42  ? 44.056  132.608 99.423  1.00 75.63  ?  41  GLU E C   1 
ATOM   4798 O O   . GLU C 3 42  ? 43.208  131.896 98.880  1.00 75.63  ?  41  GLU E O   1 
ATOM   4799 C CB  . GLU C 3 42  ? 42.496  134.545 99.103  1.00 75.63  ?  41  GLU E CB  1 
ATOM   4800 C CG  . GLU C 3 42  ? 42.059  135.943 99.509  1.00 75.63  ?  41  GLU E CG  1 
ATOM   4801 C CD  . GLU C 3 42  ? 40.851  136.426 98.731  1.00 75.63  ?  41  GLU E CD  1 
ATOM   4802 O OE1 . GLU C 3 42  ? 40.351  135.665 97.876  1.00 75.63  ?  41  GLU E OE1 1 
ATOM   4803 O OE2 . GLU C 3 42  ? 40.402  137.565 98.973  1.00 75.63  ?  41  GLU E OE2 1 
ATOM   4804 N N   . LYS C 3 43  ? 45.298  132.186 99.650  1.00 72.39  ?  42  LYS E N   1 
ATOM   4805 C CA  . LYS C 3 43  ? 45.741  130.846 99.291  1.00 72.39  ?  42  LYS E CA  1 
ATOM   4806 C C   . LYS C 3 43  ? 46.763  130.383 100.322 1.00 72.39  ?  42  LYS E C   1 
ATOM   4807 O O   . LYS C 3 43  ? 47.046  131.077 101.302 1.00 72.39  ?  42  LYS E O   1 
ATOM   4808 C CB  . LYS C 3 43  ? 46.320  130.816 97.873  1.00 72.39  ?  42  LYS E CB  1 
ATOM   4809 C CG  . LYS C 3 43  ? 45.311  131.154 96.783  1.00 72.39  ?  42  LYS E CG  1 
ATOM   4810 C CD  . LYS C 3 43  ? 45.931  131.096 95.392  1.00 72.39  ?  42  LYS E CD  1 
ATOM   4811 C CE  . LYS C 3 43  ? 46.325  129.679 95.002  1.00 72.39  ?  42  LYS E CE  1 
ATOM   4812 N NZ  . LYS C 3 43  ? 46.832  129.606 93.604  1.00 72.39  1  42  LYS E NZ  1 
ATOM   4813 N N   . GLY C 3 44  ? 47.320  129.195 100.091 1.00 70.70  ?  43  GLY E N   1 
ATOM   4814 C CA  . GLY C 3 44  ? 48.279  128.604 100.997 1.00 70.70  ?  43  GLY E CA  1 
ATOM   4815 C C   . GLY C 3 44  ? 49.709  128.983 100.658 1.00 70.70  ?  43  GLY E C   1 
ATOM   4816 O O   . GLY C 3 44  ? 49.980  129.856 99.833  1.00 70.70  ?  43  GLY E O   1 
ATOM   4817 N N   . LEU C 3 45  ? 50.638  128.299 101.320 1.00 68.19  ?  44  LEU E N   1 
ATOM   4818 C CA  . LEU C 3 45  ? 52.055  128.558 101.132 1.00 68.19  ?  44  LEU E CA  1 
ATOM   4819 C C   . LEU C 3 45  ? 52.568  127.854 99.877  1.00 68.19  ?  44  LEU E C   1 
ATOM   4820 O O   . LEU C 3 45  ? 51.907  126.988 99.298  1.00 68.19  ?  44  LEU E O   1 
ATOM   4821 C CB  . LEU C 3 45  ? 52.848  128.098 102.356 1.00 68.19  ?  44  LEU E CB  1 
ATOM   4822 C CG  . LEU C 3 45  ? 52.394  128.659 103.705 1.00 68.19  ?  44  LEU E CG  1 
ATOM   4823 C CD1 . LEU C 3 45  ? 53.246  128.096 104.830 1.00 68.19  ?  44  LEU E CD1 1 
ATOM   4824 C CD2 . LEU C 3 45  ? 52.442  130.178 103.702 1.00 68.19  ?  44  LEU E CD2 1 
ATOM   4825 N N   . GLU C 3 46  ? 53.769  128.244 99.456  1.00 66.99  ?  45  GLU E N   1 
ATOM   4826 C CA  . GLU C 3 46  ? 54.413  127.625 98.299  1.00 66.99  ?  45  GLU E CA  1 
ATOM   4827 C C   . GLU C 3 46  ? 55.901  127.927 98.363  1.00 66.99  ?  45  GLU E C   1 
ATOM   4828 O O   . GLU C 3 46  ? 56.298  129.094 98.284  1.00 66.99  ?  45  GLU E O   1 
ATOM   4829 C CB  . GLU C 3 46  ? 53.808  128.143 96.994  1.00 66.99  ?  45  GLU E CB  1 
ATOM   4830 C CG  . GLU C 3 46  ? 54.408  127.521 95.742  1.00 66.99  ?  45  GLU E CG  1 
ATOM   4831 C CD  . GLU C 3 46  ? 53.758  128.028 94.470  1.00 66.99  ?  45  GLU E CD  1 
ATOM   4832 O OE1 . GLU C 3 46  ? 52.839  128.869 94.565  1.00 66.99  ?  45  GLU E OE1 1 
ATOM   4833 O OE2 . GLU C 3 46  ? 54.165  127.586 93.376  1.00 66.99  ?  45  GLU E OE2 1 
ATOM   4834 N N   . TRP C 3 47  ? 56.718  126.886 98.504  1.00 65.51  ?  46  TRP E N   1 
ATOM   4835 C CA  . TRP C 3 47  ? 58.160  127.076 98.578  1.00 65.51  ?  46  TRP E CA  1 
ATOM   4836 C C   . TRP C 3 47  ? 58.683  127.683 97.283  1.00 65.51  ?  46  TRP E C   1 
ATOM   4837 O O   . TRP C 3 47  ? 58.183  127.391 96.193  1.00 65.51  ?  46  TRP E O   1 
ATOM   4838 C CB  . TRP C 3 47  ? 58.852  125.740 98.855  1.00 65.51  ?  46  TRP E CB  1 
ATOM   4839 C CG  . TRP C 3 47  ? 60.346  125.816 98.816  1.00 65.51  ?  46  TRP E CG  1 
ATOM   4840 C CD1 . TRP C 3 47  ? 61.171  126.262 99.806  1.00 65.51  ?  46  TRP E CD1 1 
ATOM   4841 C CD2 . TRP C 3 47  ? 61.196  125.430 97.729  1.00 65.51  ?  46  TRP E CD2 1 
ATOM   4842 N NE1 . TRP C 3 47  ? 62.482  126.179 99.404  1.00 65.51  ?  46  TRP E NE1 1 
ATOM   4843 C CE2 . TRP C 3 47  ? 62.525  125.671 98.132  1.00 65.51  ?  46  TRP E CE2 1 
ATOM   4844 C CE3 . TRP C 3 47  ? 60.963  124.904 96.455  1.00 65.51  ?  46  TRP E CE3 1 
ATOM   4845 C CZ2 . TRP C 3 47  ? 63.615  125.405 97.307  1.00 65.51  ?  46  TRP E CZ2 1 
ATOM   4846 C CZ3 . TRP C 3 47  ? 62.047  124.640 95.637  1.00 65.51  ?  46  TRP E CZ3 1 
ATOM   4847 C CH2 . TRP C 3 47  ? 63.356  124.891 96.066  1.00 65.51  ?  46  TRP E CH2 1 
ATOM   4848 N N   . VAL C 3 48  ? 59.700  128.536 97.407  1.00 65.98  ?  47  VAL E N   1 
ATOM   4849 C CA  . VAL C 3 48  ? 60.270  129.226 96.254  1.00 65.98  ?  47  VAL E CA  1 
ATOM   4850 C C   . VAL C 3 48  ? 61.732  128.838 96.090  1.00 65.98  ?  47  VAL E C   1 
ATOM   4851 O O   . VAL C 3 48  ? 62.121  128.267 95.065  1.00 65.98  ?  47  VAL E O   1 
ATOM   4852 C CB  . VAL C 3 48  ? 60.129  130.754 96.391  1.00 65.98  ?  47  VAL E CB  1 
ATOM   4853 C CG1 . VAL C 3 48  ? 60.646  131.451 95.138  1.00 65.98  ?  47  VAL E CG1 1 
ATOM   4854 C CG2 . VAL C 3 48  ? 58.686  131.132 96.659  1.00 65.98  ?  47  VAL E CG2 1 
ATOM   4855 N N   . ALA C 3 49  ? 62.553  129.143 97.094  1.00 64.92  ?  48  ALA E N   1 
ATOM   4856 C CA  . ALA C 3 49  ? 63.991  128.952 96.960  1.00 64.92  ?  48  ALA E CA  1 
ATOM   4857 C C   . ALA C 3 49  ? 64.591  128.543 98.297  1.00 64.92  ?  48  ALA E C   1 
ATOM   4858 O O   . ALA C 3 49  ? 63.999  128.752 99.357  1.00 64.92  ?  48  ALA E O   1 
ATOM   4859 C CB  . ALA C 3 49  ? 64.677  130.221 96.441  1.00 64.92  ?  48  ALA E CB  1 
ATOM   4860 N N   . TYR C 3 50  ? 65.792  127.970 98.227  1.00 63.97  ?  49  TYR E N   1 
ATOM   4861 C CA  . TYR C 3 50  ? 66.520  127.541 99.412  1.00 63.97  ?  49  TYR E CA  1 
ATOM   4862 C C   . TYR C 3 50  ? 68.012  127.717 99.175  1.00 63.97  ?  49  TYR E C   1 
ATOM   4863 O O   . TYR C 3 50  ? 68.519  127.390 98.098  1.00 63.97  ?  49  TYR E O   1 
ATOM   4864 C CB  . TYR C 3 50  ? 66.215  126.080 99.760  1.00 63.97  ?  49  TYR E CB  1 
ATOM   4865 C CG  . TYR C 3 50  ? 67.312  125.403 100.552 1.00 63.97  ?  49  TYR E CG  1 
ATOM   4866 C CD1 . TYR C 3 50  ? 67.594  125.789 101.854 1.00 63.97  ?  49  TYR E CD1 1 
ATOM   4867 C CD2 . TYR C 3 50  ? 68.063  124.377 99.996  1.00 63.97  ?  49  TYR E CD2 1 
ATOM   4868 C CE1 . TYR C 3 50  ? 68.594  125.173 102.582 1.00 63.97  ?  49  TYR E CE1 1 
ATOM   4869 C CE2 . TYR C 3 50  ? 69.066  123.755 100.715 1.00 63.97  ?  49  TYR E CE2 1 
ATOM   4870 C CZ  . TYR C 3 50  ? 69.327  124.157 102.008 1.00 63.97  ?  49  TYR E CZ  1 
ATOM   4871 O OH  . TYR C 3 50  ? 70.324  123.541 102.729 1.00 63.97  ?  49  TYR E OH  1 
ATOM   4872 N N   . ILE C 3 51  ? 68.705  128.234 100.188 1.00 63.88  ?  50  ILE E N   1 
ATOM   4873 C CA  . ILE C 3 51  ? 70.151  128.418 100.151 1.00 63.88  ?  50  ILE E CA  1 
ATOM   4874 C C   . ILE C 3 51  ? 70.742  127.810 101.416 1.00 63.88  ?  50  ILE E C   1 
ATOM   4875 O O   . ILE C 3 51  ? 70.331  128.155 102.530 1.00 63.88  ?  50  ILE E O   1 
ATOM   4876 C CB  . ILE C 3 51  ? 70.540  129.905 100.025 1.00 63.88  ?  50  ILE E CB  1 
ATOM   4877 C CG1 . ILE C 3 51  ? 72.061  130.051 99.930  1.00 63.88  ?  50  ILE E CG1 1 
ATOM   4878 C CG2 . ILE C 3 51  ? 70.006  130.705 101.203 1.00 63.88  ?  50  ILE E CG2 1 
ATOM   4879 C CD1 . ILE C 3 51  ? 72.518  131.451 99.577  1.00 63.88  ?  50  ILE E CD1 1 
ATOM   4880 N N   . SER C 3 52  ? 71.705  126.908 101.241 1.00 63.69  ?  51  SER E N   1 
ATOM   4881 C CA  . SER C 3 52  ? 72.321  126.213 102.359 1.00 63.69  ?  51  SER E CA  1 
ATOM   4882 C C   . SER C 3 52  ? 73.351  127.113 103.041 1.00 63.69  ?  51  SER E C   1 
ATOM   4883 O O   . SER C 3 52  ? 73.566  128.266 102.657 1.00 63.69  ?  51  SER E O   1 
ATOM   4884 C CB  . SER C 3 52  ? 72.964  124.914 101.881 1.00 63.69  ?  51  SER E CB  1 
ATOM   4885 O OG  . SER C 3 52  ? 73.979  125.173 100.926 1.00 63.69  ?  51  SER E OG  1 
ATOM   4886 N N   . SER C 3 53  ? 73.998  126.573 104.071 1.00 63.71  ?  52  SER E N   1 
ATOM   4887 C CA  . SER C 3 53  ? 75.012  127.325 104.796 1.00 63.71  ?  52  SER E CA  1 
ATOM   4888 C C   . SER C 3 53  ? 76.269  127.481 103.949 1.00 63.71  ?  52  SER E C   1 
ATOM   4889 O O   . SER C 3 53  ? 76.676  126.562 103.234 1.00 63.71  ?  52  SER E O   1 
ATOM   4890 C CB  . SER C 3 53  ? 75.349  126.625 106.112 1.00 63.71  ?  52  SER E CB  1 
ATOM   4891 O OG  . SER C 3 53  ? 75.844  125.317 105.881 1.00 63.71  ?  52  SER E OG  1 
ATOM   4892 N N   . GLY C 3 54  ? 76.882  128.659 104.032 1.00 65.19  ?  53  GLY E N   1 
ATOM   4893 C CA  . GLY C 3 54  ? 78.093  128.937 103.285 1.00 65.19  ?  53  GLY E CA  1 
ATOM   4894 C C   . GLY C 3 54  ? 77.874  129.010 101.788 1.00 65.19  ?  53  GLY E C   1 
ATOM   4895 O O   . GLY C 3 54  ? 78.836  128.999 101.014 1.00 65.19  ?  53  GLY E O   1 
ATOM   4896 N N   . SER C 3 55  ? 76.612  129.090 101.365 1.00 64.64  ?  54  SER E N   1 
ATOM   4897 C CA  . SER C 3 55  ? 76.262  129.165 99.947  1.00 64.64  ?  54  SER E CA  1 
ATOM   4898 C C   . SER C 3 55  ? 76.810  127.973 99.168  1.00 64.64  ?  54  SER E C   1 
ATOM   4899 O O   . SER C 3 55  ? 77.098  128.078 97.973  1.00 64.64  ?  54  SER E O   1 
ATOM   4900 C CB  . SER C 3 55  ? 76.755  130.476 99.327  1.00 64.64  ?  54  SER E CB  1 
ATOM   4901 O OG  . SER C 3 55  ? 78.168  130.566 99.377  1.00 64.64  ?  54  SER E OG  1 
ATOM   4902 N N   . GLY C 3 56  ? 76.956  126.827 99.837  1.00 63.99  ?  55  GLY E N   1 
ATOM   4903 C CA  . GLY C 3 56  ? 77.474  125.642 99.176  1.00 63.99  ?  55  GLY E CA  1 
ATOM   4904 C C   . GLY C 3 56  ? 76.476  124.933 98.289  1.00 63.99  ?  55  GLY E C   1 
ATOM   4905 O O   . GLY C 3 56  ? 76.882  124.153 97.421  1.00 63.99  ?  55  GLY E O   1 
ATOM   4906 N N   . THR C 3 57  ? 75.183  125.182 98.484  1.00 64.05  ?  56  THR E N   1 
ATOM   4907 C CA  . THR C 3 57  ? 74.147  124.548 97.683  1.00 64.05  ?  56  THR E CA  1 
ATOM   4908 C C   . THR C 3 57  ? 72.945  125.477 97.612  1.00 64.05  ?  56  THR E C   1 
ATOM   4909 O O   . THR C 3 57  ? 72.595  126.126 98.602  1.00 64.05  ?  56  THR E O   1 
ATOM   4910 C CB  . THR C 3 57  ? 73.732  123.192 98.267  1.00 64.05  ?  56  THR E CB  1 
ATOM   4911 O OG1 . THR C 3 57  ? 74.888  122.360 98.424  1.00 64.05  ?  56  THR E OG1 1 
ATOM   4912 C CG2 . THR C 3 57  ? 72.735  122.499 97.354  1.00 64.05  ?  56  THR E CG2 1 
ATOM   4913 N N   . ILE C 3 58  ? 72.320  125.536 96.439  1.00 64.27  ?  57  ILE E N   1 
ATOM   4914 C CA  . ILE C 3 58  ? 71.161  126.389 96.203  1.00 64.27  ?  57  ILE E CA  1 
ATOM   4915 C C   . ILE C 3 58  ? 70.151  125.605 95.378  1.00 64.27  ?  57  ILE E C   1 
ATOM   4916 O O   . ILE C 3 58  ? 70.523  124.856 94.469  1.00 64.27  ?  57  ILE E O   1 
ATOM   4917 C CB  . ILE C 3 58  ? 71.551  127.700 95.488  1.00 64.27  ?  57  ILE E CB  1 
ATOM   4918 C CG1 . ILE C 3 58  ? 72.691  128.397 96.236  1.00 64.27  ?  57  ILE E CG1 1 
ATOM   4919 C CG2 . ILE C 3 58  ? 70.344  128.625 95.377  1.00 64.27  ?  57  ILE E CG2 1 
ATOM   4920 C CD1 . ILE C 3 58  ? 73.157  129.687 95.590  1.00 64.27  ?  57  ILE E CD1 1 
ATOM   4921 N N   . TYR C 3 59  ? 68.869  125.779 95.697  1.00 64.38  ?  58  TYR E N   1 
ATOM   4922 C CA  . TYR C 3 59  ? 67.795  125.114 94.976  1.00 64.38  ?  58  TYR E CA  1 
ATOM   4923 C C   . TYR C 3 59  ? 66.642  126.084 94.767  1.00 64.38  ?  58  TYR E C   1 
ATOM   4924 O O   . TYR C 3 59  ? 66.419  126.992 95.573  1.00 64.38  ?  58  TYR E O   1 
ATOM   4925 C CB  . TYR C 3 59  ? 67.295  123.867 95.720  1.00 64.38  ?  58  TYR E CB  1 
ATOM   4926 C CG  . TYR C 3 59  ? 68.171  122.649 95.535  1.00 64.38  ?  58  TYR E CG  1 
ATOM   4927 C CD1 . TYR C 3 59  ? 68.017  121.822 94.430  1.00 64.38  ?  58  TYR E CD1 1 
ATOM   4928 C CD2 . TYR C 3 59  ? 69.149  122.323 96.465  1.00 64.38  ?  58  TYR E CD2 1 
ATOM   4929 C CE1 . TYR C 3 59  ? 68.813  120.706 94.255  1.00 64.38  ?  58  TYR E CE1 1 
ATOM   4930 C CE2 . TYR C 3 59  ? 69.949  121.209 96.298  1.00 64.38  ?  58  TYR E CE2 1 
ATOM   4931 C CZ  . TYR C 3 59  ? 69.777  120.405 95.192  1.00 64.38  ?  58  TYR E CZ  1 
ATOM   4932 O OH  . TYR C 3 59  ? 70.573  119.295 95.023  1.00 64.38  ?  58  TYR E OH  1 
ATOM   4933 N N   . TYR C 3 60  ? 65.909  125.877 93.675  1.00 65.71  ?  59  TYR E N   1 
ATOM   4934 C CA  . TYR C 3 60  ? 64.749  126.690 93.345  1.00 65.71  ?  59  TYR E CA  1 
ATOM   4935 C C   . TYR C 3 60  ? 63.622  125.778 92.883  1.00 65.71  ?  59  TYR E C   1 
ATOM   4936 O O   . TYR C 3 60  ? 63.841  124.616 92.531  1.00 65.71  ?  59  TYR E O   1 
ATOM   4937 C CB  . TYR C 3 60  ? 65.067  127.721 92.254  1.00 65.71  ?  59  TYR E CB  1 
ATOM   4938 C CG  . TYR C 3 60  ? 66.241  128.620 92.570  1.00 65.71  ?  59  TYR E CG  1 
ATOM   4939 C CD1 . TYR C 3 60  ? 66.065  129.805 93.271  1.00 65.71  ?  59  TYR E CD1 1 
ATOM   4940 C CD2 . TYR C 3 60  ? 67.525  128.286 92.159  1.00 65.71  ?  59  TYR E CD2 1 
ATOM   4941 C CE1 . TYR C 3 60  ? 67.135  130.631 93.559  1.00 65.71  ?  59  TYR E CE1 1 
ATOM   4942 C CE2 . TYR C 3 60  ? 68.601  129.105 92.442  1.00 65.71  ?  59  TYR E CE2 1 
ATOM   4943 C CZ  . TYR C 3 60  ? 68.400  130.276 93.142  1.00 65.71  ?  59  TYR E CZ  1 
ATOM   4944 O OH  . TYR C 3 60  ? 69.470  131.094 93.425  1.00 65.71  ?  59  TYR E OH  1 
ATOM   4945 N N   . ALA C 3 61  ? 62.408  126.320 92.886  1.00 67.87  ?  60  ALA E N   1 
ATOM   4946 C CA  . ALA C 3 61  ? 61.252  125.577 92.412  1.00 67.87  ?  60  ALA E CA  1 
ATOM   4947 C C   . ALA C 3 61  ? 61.233  125.542 90.889  1.00 67.87  ?  60  ALA E C   1 
ATOM   4948 O O   . ALA C 3 61  ? 61.720  126.457 90.218  1.00 67.87  ?  60  ALA E O   1 
ATOM   4949 C CB  . ALA C 3 61  ? 59.958  126.200 92.937  1.00 67.87  ?  60  ALA E CB  1 
ATOM   4950 N N   . ASP C 3 62  ? 60.657  124.468 90.344  1.00 69.31  ?  61  ASP E N   1 
ATOM   4951 C CA  . ASP C 3 62  ? 60.630  124.301 88.894  1.00 69.31  ?  61  ASP E CA  1 
ATOM   4952 C C   . ASP C 3 62  ? 59.938  125.470 88.204  1.00 69.31  ?  61  ASP E C   1 
ATOM   4953 O O   . ASP C 3 62  ? 60.226  125.759 87.037  1.00 69.31  ?  61  ASP E O   1 
ATOM   4954 C CB  . ASP C 3 62  ? 59.935  122.988 88.532  1.00 69.31  ?  61  ASP E CB  1 
ATOM   4955 C CG  . ASP C 3 62  ? 60.638  121.777 89.113  1.00 69.31  ?  61  ASP E CG  1 
ATOM   4956 O OD1 . ASP C 3 62  ? 61.874  121.830 89.283  1.00 69.31  ?  61  ASP E OD1 1 
ATOM   4957 O OD2 . ASP C 3 62  ? 59.954  120.772 89.400  1.00 69.31  ?  61  ASP E OD2 1 
ATOM   4958 N N   . THR C 3 63  ? 59.030  126.151 88.901  1.00 69.34  ?  62  THR E N   1 
ATOM   4959 C CA  . THR C 3 63  ? 58.298  127.267 88.320  1.00 69.34  ?  62  THR E CA  1 
ATOM   4960 C C   . THR C 3 63  ? 59.020  128.599 88.468  1.00 69.34  ?  62  THR E C   1 
ATOM   4961 O O   . THR C 3 63  ? 58.709  129.541 87.729  1.00 69.34  ?  62  THR E O   1 
ATOM   4962 C CB  . THR C 3 63  ? 56.909  127.377 88.962  1.00 69.34  ?  62  THR E CB  1 
ATOM   4963 O OG1 . THR C 3 63  ? 56.224  126.124 88.842  1.00 69.34  ?  62  THR E OG1 1 
ATOM   4964 C CG2 . THR C 3 63  ? 56.085  128.466 88.288  1.00 69.34  ?  62  THR E CG2 1 
ATOM   4965 N N   . VAL C 3 64  ? 59.977  128.702 89.392  1.00 68.42  ?  63  VAL E N   1 
ATOM   4966 C CA  . VAL C 3 64  ? 60.666  129.957 89.672  1.00 68.42  ?  63  VAL E CA  1 
ATOM   4967 C C   . VAL C 3 64  ? 62.105  129.954 89.186  1.00 68.42  ?  63  VAL E C   1 
ATOM   4968 O O   . VAL C 3 64  ? 62.800  130.969 89.346  1.00 68.42  ?  63  VAL E O   1 
ATOM   4969 C CB  . VAL C 3 64  ? 60.618  130.296 91.174  1.00 68.42  ?  63  VAL E CB  1 
ATOM   4970 C CG1 . VAL C 3 64  ? 59.180  130.277 91.680  1.00 68.42  ?  63  VAL E CG1 1 
ATOM   4971 C CG2 . VAL C 3 64  ? 61.492  129.336 91.969  1.00 68.42  ?  63  VAL E CG2 1 
ATOM   4972 N N   . LYS C 3 65  ? 62.580  128.857 88.601  1.00 69.40  ?  64  LYS E N   1 
ATOM   4973 C CA  . LYS C 3 65  ? 63.950  128.816 88.111  1.00 69.40  ?  64  LYS E CA  1 
ATOM   4974 C C   . LYS C 3 65  ? 64.155  129.845 87.005  1.00 69.40  ?  64  LYS E C   1 
ATOM   4975 O O   . LYS C 3 65  ? 63.261  130.112 86.197  1.00 69.40  ?  64  LYS E O   1 
ATOM   4976 C CB  . LYS C 3 65  ? 64.293  127.418 87.593  1.00 69.40  ?  64  LYS E CB  1 
ATOM   4977 C CG  . LYS C 3 65  ? 64.652  126.423 88.684  1.00 69.40  ?  64  LYS E CG  1 
ATOM   4978 C CD  . LYS C 3 65  ? 65.025  125.069 88.102  1.00 69.40  ?  64  LYS E CD  1 
ATOM   4979 C CE  . LYS C 3 65  ? 65.429  124.088 89.191  1.00 69.40  ?  64  LYS E CE  1 
ATOM   4980 N NZ  . LYS C 3 65  ? 65.823  122.764 88.635  1.00 69.40  1  64  LYS E NZ  1 
ATOM   4981 N N   . GLY C 3 66  ? 65.349  130.424 86.976  1.00 69.76  ?  65  GLY E N   1 
ATOM   4982 C CA  . GLY C 3 66  ? 65.730  131.406 85.974  1.00 69.76  ?  65  GLY E CA  1 
ATOM   4983 C C   . GLY C 3 66  ? 65.469  132.846 86.365  1.00 69.76  ?  65  GLY E C   1 
ATOM   4984 O O   . GLY C 3 66  ? 66.321  133.711 86.151  1.00 69.76  ?  65  GLY E O   1 
ATOM   4985 N N   . ARG C 3 67  ? 64.298  133.122 86.939  1.00 71.06  ?  66  ARG E N   1 
ATOM   4986 C CA  . ARG C 3 67  ? 63.925  134.485 87.297  1.00 71.06  ?  66  ARG E CA  1 
ATOM   4987 C C   . ARG C 3 67  ? 64.468  134.890 88.664  1.00 71.06  ?  66  ARG E C   1 
ATOM   4988 O O   . ARG C 3 67  ? 65.130  135.924 88.789  1.00 71.06  ?  66  ARG E O   1 
ATOM   4989 C CB  . ARG C 3 67  ? 62.400  134.633 87.275  1.00 71.06  ?  66  ARG E CB  1 
ATOM   4990 C CG  . ARG C 3 67  ? 61.764  134.311 85.933  1.00 71.06  ?  66  ARG E CG  1 
ATOM   4991 C CD  . ARG C 3 67  ? 60.280  134.644 85.927  1.00 71.06  ?  66  ARG E CD  1 
ATOM   4992 N NE  . ARG C 3 67  ? 59.552  133.941 86.981  1.00 71.06  ?  66  ARG E NE  1 
ATOM   4993 C CZ  . ARG C 3 67  ? 59.069  132.706 86.871  1.00 71.06  ?  66  ARG E CZ  1 
ATOM   4994 N NH1 . ARG C 3 67  ? 59.232  132.015 85.749  1.00 71.06  1  66  ARG E NH1 1 
ATOM   4995 N NH2 . ARG C 3 67  ? 58.420  132.158 87.889  1.00 71.06  ?  66  ARG E NH2 1 
ATOM   4996 N N   . PHE C 3 68  ? 64.199  134.090 89.692  1.00 69.34  ?  67  PHE E N   1 
ATOM   4997 C CA  . PHE C 3 68  ? 64.591  134.425 91.054  1.00 69.34  ?  67  PHE E CA  1 
ATOM   4998 C C   . PHE C 3 68  ? 65.970  133.858 91.361  1.00 69.34  ?  67  PHE E C   1 
ATOM   4999 O O   . PHE C 3 68  ? 66.296  132.735 90.965  1.00 69.34  ?  67  PHE E O   1 
ATOM   5000 C CB  . PHE C 3 68  ? 63.574  133.884 92.062  1.00 69.34  ?  67  PHE E CB  1 
ATOM   5001 C CG  . PHE C 3 68  ? 62.154  134.325 91.807  1.00 69.34  ?  67  PHE E CG  1 
ATOM   5002 C CD1 . PHE C 3 68  ? 61.871  135.380 90.953  1.00 69.34  ?  67  PHE E CD1 1 
ATOM   5003 C CD2 . PHE C 3 68  ? 61.100  133.681 92.434  1.00 69.34  ?  67  PHE E CD2 1 
ATOM   5004 C CE1 . PHE C 3 68  ? 60.566  135.775 90.726  1.00 69.34  ?  67  PHE E CE1 1 
ATOM   5005 C CE2 . PHE C 3 68  ? 59.795  134.074 92.211  1.00 69.34  ?  67  PHE E CE2 1 
ATOM   5006 C CZ  . PHE C 3 68  ? 59.528  135.123 91.357  1.00 69.34  ?  67  PHE E CZ  1 
ATOM   5007 N N   . THR C 3 69  ? 66.779  134.643 92.071  1.00 69.11  ?  68  THR E N   1 
ATOM   5008 C CA  . THR C 3 69  ? 68.105  134.209 92.495  1.00 69.11  ?  68  THR E CA  1 
ATOM   5009 C C   . THR C 3 69  ? 68.328  134.631 93.939  1.00 69.11  ?  68  THR E C   1 
ATOM   5010 O O   . THR C 3 69  ? 68.119  135.796 94.288  1.00 69.11  ?  68  THR E O   1 
ATOM   5011 C CB  . THR C 3 69  ? 69.204  134.788 91.593  1.00 69.11  ?  68  THR E CB  1 
ATOM   5012 O OG1 . THR C 3 69  ? 70.487  134.343 92.051  1.00 69.11  ?  68  THR E OG1 1 
ATOM   5013 C CG2 . THR C 3 69  ? 69.168  136.309 91.596  1.00 69.11  ?  68  THR E CG2 1 
ATOM   5014 N N   . ILE C 3 70  ? 68.753  133.683 94.770  1.00 65.44  ?  69  ILE E N   1 
ATOM   5015 C CA  . ILE C 3 70  ? 68.931  133.907 96.199  1.00 65.44  ?  69  ILE E CA  1 
ATOM   5016 C C   . ILE C 3 70  ? 70.418  134.014 96.506  1.00 65.44  ?  69  ILE E C   1 
ATOM   5017 O O   . ILE C 3 70  ? 71.255  133.354 95.879  1.00 65.44  ?  69  ILE E O   1 
ATOM   5018 C CB  . ILE C 3 70  ? 68.278  132.783 97.032  1.00 65.44  ?  69  ILE E CB  1 
ATOM   5019 C CG1 . ILE C 3 70  ? 68.308  133.132 98.521  1.00 65.44  ?  69  ILE E CG1 1 
ATOM   5020 C CG2 . ILE C 3 70  ? 68.983  131.454 96.789  1.00 65.44  ?  69  ILE E CG2 1 
ATOM   5021 C CD1 . ILE C 3 70  ? 67.590  132.126 99.396  1.00 65.44  ?  69  ILE E CD1 1 
ATOM   5022 N N   . SER C 3 71  ? 70.744  134.857 97.484  1.00 65.56  ?  70  SER E N   1 
ATOM   5023 C CA  . SER C 3 71  ? 72.117  135.024 97.936  1.00 65.56  ?  70  SER E CA  1 
ATOM   5024 C C   . SER C 3 71  ? 72.100  135.405 99.408  1.00 65.56  ?  70  SER E C   1 
ATOM   5025 O O   . SER C 3 71  ? 71.078  135.840 99.944  1.00 65.56  ?  70  SER E O   1 
ATOM   5026 C CB  . SER C 3 71  ? 72.857  136.085 97.113  1.00 65.56  ?  70  SER E CB  1 
ATOM   5027 O OG  . SER C 3 71  ? 72.216  137.345 97.212  1.00 65.56  ?  70  SER E OG  1 
ATOM   5028 N N   . ARG C 3 72  ? 73.249  135.239 100.061 1.00 64.34  ?  71  ARG E N   1 
ATOM   5029 C CA  . ARG C 3 72  ? 73.361  135.515 101.487 1.00 64.34  ?  71  ARG E CA  1 
ATOM   5030 C C   . ARG C 3 72  ? 74.702  136.167 101.782 1.00 64.34  ?  71  ARG E C   1 
ATOM   5031 O O   . ARG C 3 72  ? 75.747  135.676 101.345 1.00 64.34  ?  71  ARG E O   1 
ATOM   5032 C CB  . ARG C 3 72  ? 73.203  134.231 102.310 1.00 64.34  ?  71  ARG E CB  1 
ATOM   5033 C CG  . ARG C 3 72  ? 74.267  133.178 102.050 1.00 64.34  ?  71  ARG E CG  1 
ATOM   5034 C CD  . ARG C 3 72  ? 73.911  131.867 102.730 1.00 64.34  ?  71  ARG E CD  1 
ATOM   5035 N NE  . ARG C 3 72  ? 73.684  132.036 104.163 1.00 64.34  ?  71  ARG E NE  1 
ATOM   5036 C CZ  . ARG C 3 72  ? 73.175  131.100 104.958 1.00 64.34  ?  71  ARG E CZ  1 
ATOM   5037 N NH1 . ARG C 3 72  ? 72.831  129.917 104.466 1.00 64.34  1  71  ARG E NH1 1 
ATOM   5038 N NH2 . ARG C 3 72  ? 73.006  131.348 106.250 1.00 64.34  ?  71  ARG E NH2 1 
ATOM   5039 N N   . ASP C 3 73  ? 74.663  137.273 102.522 1.00 66.97  ?  72  ASP E N   1 
ATOM   5040 C CA  . ASP C 3 73  ? 75.857  137.985 102.967 1.00 66.97  ?  72  ASP E CA  1 
ATOM   5041 C C   . ASP C 3 73  ? 76.069  137.628 104.434 1.00 66.97  ?  72  ASP E C   1 
ATOM   5042 O O   . ASP C 3 73  ? 75.361  138.124 105.316 1.00 66.97  ?  72  ASP E O   1 
ATOM   5043 C CB  . ASP C 3 73  ? 75.694  139.489 102.766 1.00 66.97  ?  72  ASP E CB  1 
ATOM   5044 C CG  . ASP C 3 73  ? 76.985  140.253 102.984 1.00 66.97  ?  72  ASP E CG  1 
ATOM   5045 O OD1 . ASP C 3 73  ? 78.048  139.610 103.097 1.00 66.97  ?  72  ASP E OD1 1 
ATOM   5046 O OD2 . ASP C 3 73  ? 76.935  141.500 103.042 1.00 66.97  ?  72  ASP E OD2 1 
ATOM   5047 N N   . ASP C 3 74  ? 77.040  136.751 104.692 1.00 66.26  ?  73  ASP E N   1 
ATOM   5048 C CA  . ASP C 3 74  ? 77.295  136.251 106.037 1.00 66.26  ?  73  ASP E CA  1 
ATOM   5049 C C   . ASP C 3 74  ? 77.995  137.301 106.895 1.00 66.26  ?  73  ASP E C   1 
ATOM   5050 O O   . ASP C 3 74  ? 77.630  137.474 108.065 1.00 66.26  ?  73  ASP E O   1 
ATOM   5051 C CB  . ASP C 3 74  ? 78.127  134.967 105.981 1.00 66.26  ?  73  ASP E CB  1 
ATOM   5052 C CG  . ASP C 3 74  ? 77.375  133.815 105.345 1.00 66.26  ?  73  ASP E CG  1 
ATOM   5053 O OD1 . ASP C 3 74  ? 76.208  134.012 104.947 1.00 66.26  ?  73  ASP E OD1 1 
ATOM   5054 O OD2 . ASP C 3 74  ? 77.952  132.711 105.243 1.00 66.26  ?  73  ASP E OD2 1 
ATOM   5055 N N   . PRO C 3 75  ? 79.003  138.009 106.375 1.00 66.89  ?  74  PRO E N   1 
ATOM   5056 C CA  . PRO C 3 75  ? 79.614  139.086 107.172 1.00 66.89  ?  74  PRO E CA  1 
ATOM   5057 C C   . PRO C 3 75  ? 78.607  140.049 107.778 1.00 66.89  ?  74  PRO E C   1 
ATOM   5058 O O   . PRO C 3 75  ? 78.841  140.565 108.878 1.00 66.89  ?  74  PRO E O   1 
ATOM   5059 C CB  . PRO C 3 75  ? 80.526  139.786 106.157 1.00 66.89  ?  74  PRO E CB  1 
ATOM   5060 C CG  . PRO C 3 75  ? 80.919  138.711 105.218 1.00 66.89  ?  74  PRO E CG  1 
ATOM   5061 C CD  . PRO C 3 75  ? 79.743  137.774 105.121 1.00 66.89  ?  74  PRO E CD  1 
ATOM   5062 N N   . LYS C 3 76  ? 77.492  140.307 107.096 1.00 67.51  ?  75  LYS E N   1 
ATOM   5063 C CA  . LYS C 3 76  ? 76.461  141.211 107.588 1.00 67.51  ?  75  LYS E CA  1 
ATOM   5064 C C   . LYS C 3 76  ? 75.231  140.481 108.111 1.00 67.51  ?  75  LYS E C   1 
ATOM   5065 O O   . LYS C 3 76  ? 74.314  141.132 108.620 1.00 67.51  ?  75  LYS E O   1 
ATOM   5066 C CB  . LYS C 3 76  ? 76.041  142.186 106.482 1.00 67.51  ?  75  LYS E CB  1 
ATOM   5067 C CG  . LYS C 3 76  ? 76.977  143.373 106.295 1.00 67.51  ?  75  LYS E CG  1 
ATOM   5068 C CD  . LYS C 3 76  ? 78.353  142.948 105.807 1.00 67.51  ?  75  LYS E CD  1 
ATOM   5069 C CE  . LYS C 3 76  ? 79.223  144.152 105.482 1.00 67.51  ?  75  LYS E CE  1 
ATOM   5070 N NZ  . LYS C 3 76  ? 79.433  145.028 106.667 1.00 67.51  1  75  LYS E NZ  1 
ATOM   5071 N N   . ASN C 3 77  ? 75.187  139.155 108.004 1.00 66.65  ?  76  ASN E N   1 
ATOM   5072 C CA  . ASN C 3 77  ? 74.039  138.366 108.442 1.00 66.65  ?  76  ASN E CA  1 
ATOM   5073 C C   . ASN C 3 77  ? 72.758  138.862 107.771 1.00 66.65  ?  76  ASN E C   1 
ATOM   5074 O O   . ASN C 3 77  ? 71.813  139.313 108.421 1.00 66.65  ?  76  ASN E O   1 
ATOM   5075 C CB  . ASN C 3 77  ? 73.903  138.400 109.967 1.00 66.65  ?  76  ASN E CB  1 
ATOM   5076 C CG  . ASN C 3 77  ? 75.110  137.816 110.676 1.00 66.65  ?  76  ASN E CG  1 
ATOM   5077 O OD1 . ASN C 3 77  ? 76.218  137.816 110.142 1.00 66.65  ?  76  ASN E OD1 1 
ATOM   5078 N ND2 . ASN C 3 77  ? 74.898  137.314 111.887 1.00 66.65  ?  76  ASN E ND2 1 
ATOM   5079 N N   . THR C 3 78  ? 72.742  138.771 106.443 1.00 66.44  ?  77  THR E N   1 
ATOM   5080 C CA  . THR C 3 78  ? 71.615  139.246 105.654 1.00 66.44  ?  77  THR E CA  1 
ATOM   5081 C C   . THR C 3 78  ? 71.353  138.277 104.511 1.00 66.44  ?  77  THR E C   1 
ATOM   5082 O O   . THR C 3 78  ? 72.251  137.557 104.069 1.00 66.44  ?  77  THR E O   1 
ATOM   5083 C CB  . THR C 3 78  ? 71.872  140.656 105.099 1.00 66.44  ?  77  THR E CB  1 
ATOM   5084 O OG1 . THR C 3 78  ? 72.285  141.523 106.163 1.00 66.44  ?  77  THR E OG1 1 
ATOM   5085 C CG2 . THR C 3 78  ? 70.615  141.222 104.453 1.00 66.44  ?  77  THR E CG2 1 
ATOM   5086 N N   . LEU C 3 79  ? 70.109  138.263 104.038 1.00 66.02  ?  78  LEU E N   1 
ATOM   5087 C CA  . LEU C 3 79  ? 69.700  137.444 102.907 1.00 66.02  ?  78  LEU E CA  1 
ATOM   5088 C C   . LEU C 3 79  ? 69.053  138.334 101.856 1.00 66.02  ?  78  LEU E C   1 
ATOM   5089 O O   . LEU C 3 79  ? 68.382  139.314 102.193 1.00 66.02  ?  78  LEU E O   1 
ATOM   5090 C CB  . LEU C 3 79  ? 68.723  136.348 103.348 1.00 66.02  ?  78  LEU E CB  1 
ATOM   5091 C CG  . LEU C 3 79  ? 68.331  135.306 102.299 1.00 66.02  ?  78  LEU E CG  1 
ATOM   5092 C CD1 . LEU C 3 79  ? 69.491  134.369 101.996 1.00 66.02  ?  78  LEU E CD1 1 
ATOM   5093 C CD2 . LEU C 3 79  ? 67.123  134.522 102.777 1.00 66.02  ?  78  LEU E CD2 1 
ATOM   5094 N N   . PHE C 3 80  ? 69.257  137.997 100.584 1.00 67.21  ?  79  PHE E N   1 
ATOM   5095 C CA  . PHE C 3 80  ? 68.719  138.770 99.476  1.00 67.21  ?  79  PHE E CA  1 
ATOM   5096 C C   . PHE C 3 80  ? 68.123  137.832 98.439  1.00 67.21  ?  79  PHE E C   1 
ATOM   5097 O O   . PHE C 3 80  ? 68.652  136.743 98.192  1.00 67.21  ?  79  PHE E O   1 
ATOM   5098 C CB  . PHE C 3 80  ? 69.802  139.642 98.828  1.00 67.21  ?  79  PHE E CB  1 
ATOM   5099 C CG  . PHE C 3 80  ? 70.381  140.676 99.750  1.00 67.21  ?  79  PHE E CG  1 
ATOM   5100 C CD1 . PHE C 3 80  ? 69.797  141.927 99.863  1.00 67.21  ?  79  PHE E CD1 1 
ATOM   5101 C CD2 . PHE C 3 80  ? 71.509  140.399 100.504 1.00 67.21  ?  79  PHE E CD2 1 
ATOM   5102 C CE1 . PHE C 3 80  ? 70.327  142.882 100.710 1.00 67.21  ?  79  PHE E CE1 1 
ATOM   5103 C CE2 . PHE C 3 80  ? 72.043  141.349 101.353 1.00 67.21  ?  79  PHE E CE2 1 
ATOM   5104 C CZ  . PHE C 3 80  ? 71.451  142.592 101.456 1.00 67.21  ?  79  PHE E CZ  1 
ATOM   5105 N N   . LEU C 3 81  ? 67.013  138.259 97.842  1.00 68.20  ?  80  LEU E N   1 
ATOM   5106 C CA  . LEU C 3 81  ? 66.355  137.522 96.768  1.00 68.20  ?  80  LEU E CA  1 
ATOM   5107 C C   . LEU C 3 81  ? 66.068  138.505 95.643  1.00 68.20  ?  80  LEU E C   1 
ATOM   5108 O O   . LEU C 3 81  ? 65.231  139.401 95.797  1.00 68.20  ?  80  LEU E O   1 
ATOM   5109 C CB  . LEU C 3 81  ? 65.069  136.855 97.260  1.00 68.20  ?  80  LEU E CB  1 
ATOM   5110 C CG  . LEU C 3 81  ? 64.293  136.037 96.225  1.00 68.20  ?  80  LEU E CG  1 
ATOM   5111 C CD1 . LEU C 3 81  ? 65.148  134.906 95.675  1.00 68.20  ?  80  LEU E CD1 1 
ATOM   5112 C CD2 . LEU C 3 81  ? 63.010  135.491 96.830  1.00 68.20  ?  80  LEU E CD2 1 
ATOM   5113 N N   . GLN C 3 82  ? 66.773  138.353 94.526  1.00 71.00  ?  81  GLN E N   1 
ATOM   5114 C CA  . GLN C 3 82  ? 66.613  139.224 93.369  1.00 71.00  ?  81  GLN E CA  1 
ATOM   5115 C C   . GLN C 3 82  ? 65.682  138.548 92.372  1.00 71.00  ?  81  GLN E C   1 
ATOM   5116 O O   . GLN C 3 82  ? 65.960  137.435 91.911  1.00 71.00  ?  81  GLN E O   1 
ATOM   5117 C CB  . GLN C 3 82  ? 67.967  139.532 92.729  1.00 71.00  ?  81  GLN E CB  1 
ATOM   5118 C CG  . GLN C 3 82  ? 67.892  140.306 91.418  1.00 71.00  ?  81  GLN E CG  1 
ATOM   5119 C CD  . GLN C 3 82  ? 67.238  141.666 91.572  1.00 71.00  ?  81  GLN E CD  1 
ATOM   5120 O OE1 . GLN C 3 82  ? 66.956  142.111 92.684  1.00 71.00  ?  81  GLN E OE1 1 
ATOM   5121 N NE2 . GLN C 3 82  ? 66.994  142.334 90.451  1.00 71.00  ?  81  GLN E NE2 1 
ATOM   5122 N N   . MET C 3 83  ? 64.579  139.218 92.051  1.00 70.52  ?  82  MET E N   1 
ATOM   5123 C CA  . MET C 3 83  ? 63.596  138.729 91.098  1.00 70.52  ?  82  MET E CA  1 
ATOM   5124 C C   . MET C 3 83  ? 63.627  139.603 89.853  1.00 70.52  ?  82  MET E C   1 
ATOM   5125 O O   . MET C 3 83  ? 63.699  140.833 89.949  1.00 70.52  ?  82  MET E O   1 
ATOM   5126 C CB  . MET C 3 83  ? 62.192  138.742 91.707  1.00 70.52  ?  82  MET E CB  1 
ATOM   5127 C CG  . MET C 3 83  ? 62.097  138.068 93.066  1.00 70.52  ?  82  MET E CG  1 
ATOM   5128 S SD  . MET C 3 83  ? 60.422  138.080 93.730  1.00 70.52  ?  82  MET E SD  1 
ATOM   5129 C CE  . MET C 3 83  ? 60.676  137.248 95.295  1.00 70.52  ?  82  MET E CE  1 
ATOM   5130 N N   . THR C 3 84  ? 63.576  138.961 88.688  1.00 72.33  ?  83  THR E N   1 
ATOM   5131 C CA  . THR C 3 84  ? 63.587  139.648 87.407  1.00 72.33  ?  83  THR E CA  1 
ATOM   5132 C C   . THR C 3 84  ? 62.464  139.109 86.533  1.00 72.33  ?  83  THR E C   1 
ATOM   5133 O O   . THR C 3 84  ? 62.061  137.950 86.658  1.00 72.33  ?  83  THR E O   1 
ATOM   5134 C CB  . THR C 3 84  ? 64.932  139.477 86.684  1.00 72.33  ?  83  THR E CB  1 
ATOM   5135 O OG1 . THR C 3 84  ? 65.173  138.087 86.435  1.00 72.33  ?  83  THR E OG1 1 
ATOM   5136 C CG2 . THR C 3 84  ? 66.068  140.044 87.523  1.00 72.33  ?  83  THR E CG2 1 
ATOM   5137 N N   . SER C 3 85  ? 61.964  139.965 85.642  1.00 73.25  ?  84  SER E N   1 
ATOM   5138 C CA  . SER C 3 85  ? 60.864  139.610 84.747  1.00 73.25  ?  84  SER E CA  1 
ATOM   5139 C C   . SER C 3 85  ? 59.654  139.125 85.546  1.00 73.25  ?  84  SER E C   1 
ATOM   5140 O O   . SER C 3 85  ? 59.079  138.069 85.273  1.00 73.25  ?  84  SER E O   1 
ATOM   5141 C CB  . SER C 3 85  ? 61.307  138.557 83.728  1.00 73.25  ?  84  SER E CB  1 
ATOM   5142 O OG  . SER C 3 85  ? 61.675  137.347 84.367  1.00 73.25  ?  84  SER E OG  1 
ATOM   5143 N N   . LEU C 3 86  ? 59.272  139.913 86.548  1.00 72.30  ?  85  LEU E N   1 
ATOM   5144 C CA  . LEU C 3 86  ? 58.152  139.547 87.404  1.00 72.30  ?  85  LEU E CA  1 
ATOM   5145 C C   . LEU C 3 86  ? 56.869  139.434 86.591  1.00 72.30  ?  85  LEU E C   1 
ATOM   5146 O O   . LEU C 3 86  ? 56.538  140.322 85.800  1.00 72.30  ?  85  LEU E O   1 
ATOM   5147 C CB  . LEU C 3 86  ? 57.981  140.580 88.518  1.00 72.30  ?  85  LEU E CB  1 
ATOM   5148 C CG  . LEU C 3 86  ? 59.068  140.592 89.595  1.00 72.30  ?  85  LEU E CG  1 
ATOM   5149 C CD1 . LEU C 3 86  ? 58.888  141.785 90.521  1.00 72.30  ?  85  LEU E CD1 1 
ATOM   5150 C CD2 . LEU C 3 86  ? 59.051  139.294 90.387  1.00 72.30  ?  85  LEU E CD2 1 
ATOM   5151 N N   . ARG C 3 87  ? 56.146  138.334 86.791  1.00 72.42  ?  86  ARG E N   1 
ATOM   5152 C CA  . ARG C 3 87  ? 54.886  138.098 86.109  1.00 72.42  ?  86  ARG E CA  1 
ATOM   5153 C C   . ARG C 3 87  ? 53.723  138.584 86.974  1.00 72.42  ?  86  ARG E C   1 
ATOM   5154 O O   . ARG C 3 87  ? 53.898  139.015 88.116  1.00 72.42  ?  86  ARG E O   1 
ATOM   5155 C CB  . ARG C 3 87  ? 54.738  136.616 85.769  1.00 72.42  ?  86  ARG E CB  1 
ATOM   5156 C CG  . ARG C 3 87  ? 55.856  136.070 84.897  1.00 72.42  ?  86  ARG E CG  1 
ATOM   5157 C CD  . ARG C 3 87  ? 55.682  134.585 84.625  1.00 72.42  ?  86  ARG E CD  1 
ATOM   5158 N NE  . ARG C 3 87  ? 56.767  134.049 83.808  1.00 72.42  ?  86  ARG E NE  1 
ATOM   5159 C CZ  . ARG C 3 87  ? 56.871  132.776 83.437  1.00 72.42  ?  86  ARG E CZ  1 
ATOM   5160 N NH1 . ARG C 3 87  ? 55.953  131.893 83.809  1.00 72.42  1  86  ARG E NH1 1 
ATOM   5161 N NH2 . ARG C 3 87  ? 57.895  132.385 82.692  1.00 72.42  ?  86  ARG E NH2 1 
ATOM   5162 N N   . SER C 3 88  ? 52.511  138.514 86.417  1.00 73.63  ?  87  SER E N   1 
ATOM   5163 C CA  . SER C 3 88  ? 51.335  138.969 87.151  1.00 73.63  ?  87  SER E CA  1 
ATOM   5164 C C   . SER C 3 88  ? 51.034  138.075 88.347  1.00 73.63  ?  87  SER E C   1 
ATOM   5165 O O   . SER C 3 88  ? 50.583  138.567 89.388  1.00 73.63  ?  87  SER E O   1 
ATOM   5166 C CB  . SER C 3 88  ? 50.126  139.025 86.217  1.00 73.63  ?  87  SER E CB  1 
ATOM   5167 O OG  . SER C 3 88  ? 48.969  139.466 86.906  1.00 73.63  ?  87  SER E OG  1 
ATOM   5168 N N   . GLU C 3 89  ? 51.275  136.769 88.222  1.00 73.40  ?  88  GLU E N   1 
ATOM   5169 C CA  . GLU C 3 89  ? 50.992  135.838 89.308  1.00 73.40  ?  88  GLU E CA  1 
ATOM   5170 C C   . GLU C 3 89  ? 51.931  136.013 90.494  1.00 73.40  ?  88  GLU E C   1 
ATOM   5171 O O   . GLU C 3 89  ? 51.640  135.486 91.574  1.00 73.40  ?  88  GLU E O   1 
ATOM   5172 C CB  . GLU C 3 89  ? 51.071  134.401 88.783  1.00 73.40  ?  88  GLU E CB  1 
ATOM   5173 C CG  . GLU C 3 89  ? 50.751  133.323 89.816  1.00 73.40  ?  88  GLU E CG  1 
ATOM   5174 C CD  . GLU C 3 89  ? 51.974  132.848 90.584  1.00 73.40  ?  88  GLU E CD  1 
ATOM   5175 O OE1 . GLU C 3 89  ? 53.089  133.336 90.303  1.00 73.40  ?  88  GLU E OE1 1 
ATOM   5176 O OE2 . GLU C 3 89  ? 51.817  131.983 91.471  1.00 73.40  ?  88  GLU E OE2 1 
ATOM   5177 N N   . ASP C 3 90  ? 53.035  136.745 90.331  1.00 71.83  ?  89  ASP E N   1 
ATOM   5178 C CA  . ASP C 3 90  ? 54.009  136.888 91.406  1.00 71.83  ?  89  ASP E CA  1 
ATOM   5179 C C   . ASP C 3 90  ? 53.461  137.636 92.614  1.00 71.83  ?  89  ASP E C   1 
ATOM   5180 O O   . ASP C 3 90  ? 54.119  137.647 93.660  1.00 71.83  ?  89  ASP E O   1 
ATOM   5181 C CB  . ASP C 3 90  ? 55.258  137.601 90.885  1.00 71.83  ?  89  ASP E CB  1 
ATOM   5182 C CG  . ASP C 3 90  ? 55.994  136.794 89.835  1.00 71.83  ?  89  ASP E CG  1 
ATOM   5183 O OD1 . ASP C 3 90  ? 55.917  135.549 89.877  1.00 71.83  ?  89  ASP E OD1 1 
ATOM   5184 O OD2 . ASP C 3 90  ? 56.650  137.406 88.966  1.00 71.83  ?  89  ASP E OD2 1 
ATOM   5185 N N   . THR C 3 91  ? 52.288  138.260 92.502  1.00 71.08  ?  90  THR E N   1 
ATOM   5186 C CA  . THR C 3 91  ? 51.698  138.962 93.636  1.00 71.08  ?  90  THR E CA  1 
ATOM   5187 C C   . THR C 3 91  ? 51.503  138.003 94.804  1.00 71.08  ?  90  THR E C   1 
ATOM   5188 O O   . THR C 3 91  ? 50.711  137.060 94.716  1.00 71.08  ?  90  THR E O   1 
ATOM   5189 C CB  . THR C 3 91  ? 50.365  139.610 93.242  1.00 71.08  ?  90  THR E CB  1 
ATOM   5190 O OG1 . THR C 3 91  ? 49.804  140.283 94.376  1.00 71.08  ?  90  THR E OG1 1 
ATOM   5191 C CG2 . THR C 3 91  ? 49.371  138.570 92.729  1.00 71.08  ?  90  THR E CG2 1 
ATOM   5192 N N   . ALA C 3 92  ? 52.226  138.227 95.899  1.00 70.68  ?  91  ALA E N   1 
ATOM   5193 C CA  . ALA C 3 92  ? 52.179  137.326 97.045  1.00 70.68  ?  91  ALA E CA  1 
ATOM   5194 C C   . ALA C 3 92  ? 53.043  137.911 98.156  1.00 70.68  ?  91  ALA E C   1 
ATOM   5195 O O   . ALA C 3 92  ? 53.741  138.911 97.968  1.00 70.68  ?  91  ALA E O   1 
ATOM   5196 C CB  . ALA C 3 92  ? 52.658  135.921 96.674  1.00 70.68  ?  91  ALA E CB  1 
ATOM   5197 N N   . MET C 3 93  ? 52.989  137.267 99.319  1.00 71.23  ?  92  MET E N   1 
ATOM   5198 C CA  . MET C 3 93  ? 53.807  137.635 100.466 1.00 71.23  ?  92  MET E CA  1 
ATOM   5199 C C   . MET C 3 93  ? 54.904  136.595 100.644 1.00 71.23  ?  92  MET E C   1 
ATOM   5200 O O   . MET C 3 93  ? 54.620  135.396 100.729 1.00 71.23  ?  92  MET E O   1 
ATOM   5201 C CB  . MET C 3 93  ? 52.958  137.739 101.735 1.00 71.23  ?  92  MET E CB  1 
ATOM   5202 C CG  . MET C 3 93  ? 53.712  138.274 102.943 1.00 71.23  ?  92  MET E CG  1 
ATOM   5203 S SD  . MET C 3 93  ? 52.661  138.505 104.392 1.00 71.23  ?  92  MET E SD  1 
ATOM   5204 C CE  . MET C 3 93  ? 51.562  139.800 103.824 1.00 71.23  ?  92  MET E CE  1 
ATOM   5205 N N   . TYR C 3 94  ? 56.151  137.053 100.687 1.00 68.41  ?  93  TYR E N   1 
ATOM   5206 C CA  . TYR C 3 94  ? 57.306  136.175 100.799 1.00 68.41  ?  93  TYR E CA  1 
ATOM   5207 C C   . TYR C 3 94  ? 57.828  136.176 102.229 1.00 68.41  ?  93  TYR E C   1 
ATOM   5208 O O   . TYR C 3 94  ? 57.859  137.218 102.891 1.00 68.41  ?  93  TYR E O   1 
ATOM   5209 C CB  . TYR C 3 94  ? 58.412  136.610 99.836  1.00 68.41  ?  93  TYR E CB  1 
ATOM   5210 C CG  . TYR C 3 94  ? 57.997  136.576 98.382  1.00 68.41  ?  93  TYR E CG  1 
ATOM   5211 C CD1 . TYR C 3 94  ? 57.408  137.681 97.782  1.00 68.41  ?  93  TYR E CD1 1 
ATOM   5212 C CD2 . TYR C 3 94  ? 58.190  135.438 97.611  1.00 68.41  ?  93  TYR E CD2 1 
ATOM   5213 C CE1 . TYR C 3 94  ? 57.026  137.654 96.454  1.00 68.41  ?  93  TYR E CE1 1 
ATOM   5214 C CE2 . TYR C 3 94  ? 57.811  135.401 96.283  1.00 68.41  ?  93  TYR E CE2 1 
ATOM   5215 C CZ  . TYR C 3 94  ? 57.229  136.512 95.710  1.00 68.41  ?  93  TYR E CZ  1 
ATOM   5216 O OH  . TYR C 3 94  ? 56.850  136.481 94.387  1.00 68.41  ?  93  TYR E OH  1 
ATOM   5217 N N   . TYR C 3 95  ? 58.236  134.999 102.699 1.00 66.91  ?  94  TYR E N   1 
ATOM   5218 C CA  . TYR C 3 95  ? 58.743  134.810 104.048 1.00 66.91  ?  94  TYR E CA  1 
ATOM   5219 C C   . TYR C 3 95  ? 60.092  134.108 103.994 1.00 66.91  ?  94  TYR E C   1 
ATOM   5220 O O   . TYR C 3 95  ? 60.299  133.195 103.186 1.00 66.91  ?  94  TYR E O   1 
ATOM   5221 C CB  . TYR C 3 95  ? 57.771  133.982 104.897 1.00 66.91  ?  94  TYR E CB  1 
ATOM   5222 C CG  . TYR C 3 95  ? 56.343  134.476 104.868 1.00 66.91  ?  94  TYR E CG  1 
ATOM   5223 C CD1 . TYR C 3 95  ? 55.881  135.383 105.812 1.00 66.91  ?  94  TYR E CD1 1 
ATOM   5224 C CD2 . TYR C 3 95  ? 55.453  134.028 103.901 1.00 66.91  ?  94  TYR E CD2 1 
ATOM   5225 C CE1 . TYR C 3 95  ? 54.575  135.834 105.791 1.00 66.91  ?  94  TYR E CE1 1 
ATOM   5226 C CE2 . TYR C 3 95  ? 54.146  134.473 103.871 1.00 66.91  ?  94  TYR E CE2 1 
ATOM   5227 C CZ  . TYR C 3 95  ? 53.712  135.375 104.818 1.00 66.91  ?  94  TYR E CZ  1 
ATOM   5228 O OH  . TYR C 3 95  ? 52.411  135.822 104.793 1.00 66.91  ?  94  TYR E OH  1 
ATOM   5229 N N   . CYS C 3 96  ? 61.003  134.542 104.860 1.00 65.72  ?  95  CYS E N   1 
ATOM   5230 C CA  . CYS C 3 96  ? 62.306  133.913 105.023 1.00 65.72  ?  95  CYS E CA  1 
ATOM   5231 C C   . CYS C 3 96  ? 62.298  133.075 106.294 1.00 65.72  ?  95  CYS E C   1 
ATOM   5232 O O   . CYS C 3 96  ? 61.922  133.567 107.364 1.00 65.72  ?  95  CYS E O   1 
ATOM   5233 C CB  . CYS C 3 96  ? 63.416  134.963 105.085 1.00 65.72  ?  95  CYS E CB  1 
ATOM   5234 S SG  . CYS C 3 96  ? 65.055  134.285 105.424 1.00 65.72  ?  95  CYS E SG  1 
ATOM   5235 N N   . VAL C 3 97  ? 62.711  131.816 106.174 1.00 63.55  ?  96  VAL E N   1 
ATOM   5236 C CA  . VAL C 3 97  ? 62.664  130.862 107.275 1.00 63.55  ?  96  VAL E CA  1 
ATOM   5237 C C   . VAL C 3 97  ? 64.048  130.259 107.462 1.00 63.55  ?  96  VAL E C   1 
ATOM   5238 O O   . VAL C 3 97  ? 64.749  129.971 106.486 1.00 63.55  ?  96  VAL E O   1 
ATOM   5239 C CB  . VAL C 3 97  ? 61.622  129.753 107.018 1.00 63.55  ?  96  VAL E CB  1 
ATOM   5240 C CG1 . VAL C 3 97  ? 61.515  128.829 108.221 1.00 63.55  ?  96  VAL E CG1 1 
ATOM   5241 C CG2 . VAL C 3 97  ? 60.267  130.359 106.681 1.00 63.55  ?  96  VAL E CG2 1 
ATOM   5242 N N   . ARG C 3 98  ? 64.438  130.069 108.719 1.00 62.43  ?  97  ARG E N   1 
ATOM   5243 C CA  . ARG C 3 98  ? 65.703  129.439 109.067 1.00 62.43  ?  97  ARG E CA  1 
ATOM   5244 C C   . ARG C 3 98  ? 65.489  127.955 109.335 1.00 62.43  ?  97  ARG E C   1 
ATOM   5245 O O   . ARG C 3 98  ? 64.450  127.544 109.858 1.00 62.43  ?  97  ARG E O   1 
ATOM   5246 C CB  . ARG C 3 98  ? 66.325  130.105 110.297 1.00 62.43  ?  97  ARG E CB  1 
ATOM   5247 C CG  . ARG C 3 98  ? 65.510  129.941 111.574 1.00 62.43  ?  97  ARG E CG  1 
ATOM   5248 C CD  . ARG C 3 98  ? 66.241  130.507 112.779 1.00 62.43  ?  97  ARG E CD  1 
ATOM   5249 N NE  . ARG C 3 98  ? 65.569  130.168 114.031 1.00 62.43  ?  97  ARG E NE  1 
ATOM   5250 C CZ  . ARG C 3 98  ? 66.034  130.474 115.239 1.00 62.43  ?  97  ARG E CZ  1 
ATOM   5251 N NH1 . ARG C 3 98  ? 67.180  131.130 115.369 1.00 62.43  1  97  ARG E NH1 1 
ATOM   5252 N NH2 . ARG C 3 98  ? 65.352  130.123 116.320 1.00 62.43  ?  97  ARG E NH2 1 
ATOM   5253 N N   . SER C 3 99  ? 66.485  127.150 108.970 1.00 61.45  ?  98  SER E N   1 
ATOM   5254 C CA  . SER C 3 99  ? 66.412  125.712 109.191 1.00 61.45  ?  98  SER E CA  1 
ATOM   5255 C C   . SER C 3 99  ? 67.817  125.145 109.308 1.00 61.45  ?  98  SER E C   1 
ATOM   5256 O O   . SER C 3 99  ? 68.655  125.370 108.430 1.00 61.45  ?  98  SER E O   1 
ATOM   5257 C CB  . SER C 3 99  ? 65.656  125.018 108.054 1.00 61.45  ?  98  SER E CB  1 
ATOM   5258 O OG  . SER C 3 99  ? 64.340  125.527 107.926 1.00 61.45  ?  98  SER E OG  1 
ATOM   5259 N N   . ILE C 3 100 ? 68.066  124.414 110.392 1.00 60.33  ?  99  ILE E N   1 
ATOM   5260 C CA  . ILE C 3 100 ? 69.319  123.699 110.607 1.00 60.33  ?  99  ILE E CA  1 
ATOM   5261 C C   . ILE C 3 100 ? 69.003  122.210 110.627 1.00 60.33  ?  99  ILE E C   1 
ATOM   5262 O O   . ILE C 3 100 ? 68.046  121.784 111.285 1.00 60.33  ?  99  ILE E O   1 
ATOM   5263 C CB  . ILE C 3 100 ? 70.012  124.138 111.910 1.00 60.33  ?  99  ILE E CB  1 
ATOM   5264 C CG1 . ILE C 3 100 ? 71.404  123.511 112.008 1.00 60.33  ?  99  ILE E CG1 1 
ATOM   5265 C CG2 . ILE C 3 100 ? 69.167  123.764 113.122 1.00 60.33  ?  99  ILE E CG2 1 
ATOM   5266 C CD1 . ILE C 3 100 ? 72.223  124.018 113.176 1.00 60.33  ?  99  ILE E CD1 1 
ATOM   5267 N N   . TYR C 3 101 ? 69.801  121.425 109.908 1.00 60.36  ?  100 TYR E N   1 
ATOM   5268 C CA  . TYR C 3 101 ? 69.523  120.010 109.680 1.00 60.36  ?  100 TYR E CA  1 
ATOM   5269 C C   . TYR C 3 101 ? 70.537  119.164 110.443 1.00 60.36  ?  100 TYR E C   1 
ATOM   5270 O O   . TYR C 3 101 ? 71.731  119.178 110.127 1.00 60.36  ?  100 TYR E O   1 
ATOM   5271 C CB  . TYR C 3 101 ? 69.558  119.690 108.188 1.00 60.36  ?  100 TYR E CB  1 
ATOM   5272 C CG  . TYR C 3 101 ? 68.537  120.459 107.379 1.00 60.36  ?  100 TYR E CG  1 
ATOM   5273 C CD1 . TYR C 3 101 ? 67.270  119.939 107.151 1.00 60.36  ?  100 TYR E CD1 1 
ATOM   5274 C CD2 . TYR C 3 101 ? 68.839  121.706 106.848 1.00 60.36  ?  100 TYR E CD2 1 
ATOM   5275 C CE1 . TYR C 3 101 ? 66.333  120.638 106.414 1.00 60.36  ?  100 TYR E CE1 1 
ATOM   5276 C CE2 . TYR C 3 101 ? 67.909  122.412 106.110 1.00 60.36  ?  100 TYR E CE2 1 
ATOM   5277 C CZ  . TYR C 3 101 ? 66.658  121.874 105.896 1.00 60.36  ?  100 TYR E CZ  1 
ATOM   5278 O OH  . TYR C 3 101 ? 65.728  122.574 105.161 1.00 60.36  ?  100 TYR E OH  1 
ATOM   5279 N N   . TYR C 3 102 ? 70.054  118.432 111.444 1.00 57.50  ?  101 TYR E N   1 
ATOM   5280 C CA  . TYR C 3 102 ? 70.858  117.456 112.168 1.00 57.50  ?  101 TYR E CA  1 
ATOM   5281 C C   . TYR C 3 102 ? 69.922  116.638 113.043 1.00 57.50  ?  101 TYR E C   1 
ATOM   5282 O O   . TYR C 3 102 ? 68.780  117.034 113.297 1.00 57.50  ?  101 TYR E O   1 
ATOM   5283 C CB  . TYR C 3 102 ? 71.953  118.123 113.011 1.00 57.50  ?  101 TYR E CB  1 
ATOM   5284 C CG  . TYR C 3 102 ? 71.438  119.018 114.116 1.00 57.50  ?  101 TYR E CG  1 
ATOM   5285 C CD1 . TYR C 3 102 ? 71.113  118.499 115.363 1.00 57.50  ?  101 TYR E CD1 1 
ATOM   5286 C CD2 . TYR C 3 102 ? 71.288  120.383 113.917 1.00 57.50  ?  101 TYR E CD2 1 
ATOM   5287 C CE1 . TYR C 3 102 ? 70.645  119.313 116.377 1.00 57.50  ?  101 TYR E CE1 1 
ATOM   5288 C CE2 . TYR C 3 102 ? 70.821  121.206 114.926 1.00 57.50  ?  101 TYR E CE2 1 
ATOM   5289 C CZ  . TYR C 3 102 ? 70.502  120.665 116.153 1.00 57.50  ?  101 TYR E CZ  1 
ATOM   5290 O OH  . TYR C 3 102 ? 70.037  121.480 117.160 1.00 57.50  ?  101 TYR E OH  1 
ATOM   5291 N N   . TYR C 3 103 ? 70.417  115.488 113.498 1.00 56.53  ?  102 TYR E N   1 
ATOM   5292 C CA  . TYR C 3 103 ? 69.598  114.594 114.305 1.00 56.53  ?  102 TYR E CA  1 
ATOM   5293 C C   . TYR C 3 103 ? 69.115  115.302 115.564 1.00 56.53  ?  102 TYR E C   1 
ATOM   5294 O O   . TYR C 3 103 ? 69.909  115.875 116.315 1.00 56.53  ?  102 TYR E O   1 
ATOM   5295 C CB  . TYR C 3 103 ? 70.389  113.340 114.675 1.00 56.53  ?  102 TYR E CB  1 
ATOM   5296 C CG  . TYR C 3 103 ? 69.646  112.409 115.605 1.00 56.53  ?  102 TYR E CG  1 
ATOM   5297 C CD1 . TYR C 3 103 ? 68.570  111.657 115.152 1.00 56.53  ?  102 TYR E CD1 1 
ATOM   5298 C CD2 . TYR C 3 103 ? 70.019  112.282 116.936 1.00 56.53  ?  102 TYR E CD2 1 
ATOM   5299 C CE1 . TYR C 3 103 ? 67.887  110.804 115.998 1.00 56.53  ?  102 TYR E CE1 1 
ATOM   5300 C CE2 . TYR C 3 103 ? 69.342  111.432 117.790 1.00 56.53  ?  102 TYR E CE2 1 
ATOM   5301 C CZ  . TYR C 3 103 ? 68.277  110.696 117.316 1.00 56.53  ?  102 TYR E CZ  1 
ATOM   5302 O OH  . TYR C 3 103 ? 67.600  109.848 118.163 1.00 56.53  ?  102 TYR E OH  1 
ATOM   5303 N N   . GLY C 3 104 ? 67.804  115.258 115.792 1.00 59.52  ?  103 GLY E N   1 
ATOM   5304 C CA  . GLY C 3 104 ? 67.200  115.927 116.924 1.00 59.52  ?  103 GLY E CA  1 
ATOM   5305 C C   . GLY C 3 104 ? 66.872  117.386 116.699 1.00 59.52  ?  103 GLY E C   1 
ATOM   5306 O O   . GLY C 3 104 ? 66.379  118.041 117.627 1.00 59.52  ?  103 GLY E O   1 
ATOM   5307 N N   . SER C 3 105 ? 67.125  117.916 115.506 1.00 59.39  ?  104 SER E N   1 
ATOM   5308 C CA  . SER C 3 105 ? 66.862  119.315 115.215 1.00 59.39  ?  104 SER E CA  1 
ATOM   5309 C C   . SER C 3 105 ? 65.378  119.526 114.922 1.00 59.39  ?  104 SER E C   1 
ATOM   5310 O O   . SER C 3 105 ? 64.563  118.602 114.982 1.00 59.39  ?  104 SER E O   1 
ATOM   5311 C CB  . SER C 3 105 ? 67.720  119.780 114.041 1.00 59.39  ?  104 SER E CB  1 
ATOM   5312 O OG  . SER C 3 105 ? 67.376  119.086 112.853 1.00 59.39  ?  104 SER E OG  1 
ATOM   5313 N N   . SER C 3 106 ? 65.025  120.768 114.599 1.00 61.51  ?  105 SER E N   1 
ATOM   5314 C CA  . SER C 3 106 ? 63.652  121.139 114.257 1.00 61.51  ?  105 SER E CA  1 
ATOM   5315 C C   . SER C 3 106 ? 63.699  122.142 113.115 1.00 61.51  ?  105 SER E C   1 
ATOM   5316 O O   . SER C 3 106 ? 63.529  123.350 113.316 1.00 61.51  ?  105 SER E O   1 
ATOM   5317 C CB  . SER C 3 106 ? 62.918  121.716 115.470 1.00 61.51  ?  105 SER E CB  1 
ATOM   5318 O OG  . SER C 3 106 ? 63.593  122.852 115.983 1.00 61.51  ?  105 SER E OG  1 
ATOM   5319 N N   . PRO C 3 107 ? 63.941  121.672 111.891 1.00 61.34  ?  106 PRO E N   1 
ATOM   5320 C CA  . PRO C 3 107 ? 64.004  122.593 110.751 1.00 61.34  ?  106 PRO E CA  1 
ATOM   5321 C C   . PRO C 3 107 ? 62.739  123.430 110.631 1.00 61.34  ?  106 PRO E C   1 
ATOM   5322 O O   . PRO C 3 107 ? 61.641  122.996 110.986 1.00 61.34  ?  106 PRO E O   1 
ATOM   5323 C CB  . PRO C 3 107 ? 64.174  121.657 109.548 1.00 61.34  ?  106 PRO E CB  1 
ATOM   5324 C CG  . PRO C 3 107 ? 64.802  120.430 110.114 1.00 61.34  ?  106 PRO E CG  1 
ATOM   5325 C CD  . PRO C 3 107 ? 64.241  120.284 111.499 1.00 61.34  ?  106 PRO E CD  1 
ATOM   5326 N N   . PHE C 3 108 ? 62.910  124.650 110.121 1.00 62.97  ?  107 PHE E N   1 
ATOM   5327 C CA  . PHE C 3 108 ? 61.802  125.588 109.941 1.00 62.97  ?  107 PHE E CA  1 
ATOM   5328 C C   . PHE C 3 108 ? 61.145  125.913 111.282 1.00 62.97  ?  107 PHE E C   1 
ATOM   5329 O O   . PHE C 3 108 ? 59.925  125.839 111.438 1.00 62.97  ?  107 PHE E O   1 
ATOM   5330 C CB  . PHE C 3 108 ? 60.775  125.037 108.949 1.00 62.97  ?  107 PHE E CB  1 
ATOM   5331 C CG  . PHE C 3 108 ? 61.362  124.648 107.621 1.00 62.97  ?  107 PHE E CG  1 
ATOM   5332 C CD1 . PHE C 3 108 ? 61.864  123.373 107.418 1.00 62.97  ?  107 PHE E CD1 1 
ATOM   5333 C CD2 . PHE C 3 108 ? 61.407  125.555 106.576 1.00 62.97  ?  107 PHE E CD2 1 
ATOM   5334 C CE1 . PHE C 3 108 ? 62.403  123.012 106.198 1.00 62.97  ?  107 PHE E CE1 1 
ATOM   5335 C CE2 . PHE C 3 108 ? 61.944  125.198 105.354 1.00 62.97  ?  107 PHE E CE2 1 
ATOM   5336 C CZ  . PHE C 3 108 ? 62.442  123.925 105.165 1.00 62.97  ?  107 PHE E CZ  1 
ATOM   5337 N N   . ASP C 3 109 ? 61.973  126.284 112.259 1.00 63.36  ?  108 ASP E N   1 
ATOM   5338 C CA  . ASP C 3 109 ? 61.487  126.554 113.606 1.00 63.36  ?  108 ASP E CA  1 
ATOM   5339 C C   . ASP C 3 109 ? 61.061  128.001 113.807 1.00 63.36  ?  108 ASP E C   1 
ATOM   5340 O O   . ASP C 3 109 ? 60.227  128.276 114.677 1.00 63.36  ?  108 ASP E O   1 
ATOM   5341 C CB  . ASP C 3 109 ? 62.565  126.201 114.636 1.00 63.36  ?  108 ASP E CB  1 
ATOM   5342 C CG  . ASP C 3 109 ? 63.859  126.961 114.412 1.00 63.36  ?  108 ASP E CG  1 
ATOM   5343 O OD1 . ASP C 3 109 ? 63.942  127.722 113.425 1.00 63.36  ?  108 ASP E OD1 1 
ATOM   5344 O OD2 . ASP C 3 109 ? 64.793  126.797 115.225 1.00 63.36  ?  108 ASP E OD2 1 
ATOM   5345 N N   . PHE C 3 110 ? 61.609  128.932 113.028 1.00 63.13  ?  109 PHE E N   1 
ATOM   5346 C CA  . PHE C 3 110 ? 61.307  130.352 113.169 1.00 63.13  ?  109 PHE E CA  1 
ATOM   5347 C C   . PHE C 3 110 ? 60.964  130.919 111.800 1.00 63.13  ?  109 PHE E C   1 
ATOM   5348 O O   . PHE C 3 110 ? 61.764  130.814 110.865 1.00 63.13  ?  109 PHE E O   1 
ATOM   5349 C CB  . PHE C 3 110 ? 62.487  131.109 113.785 1.00 63.13  ?  109 PHE E CB  1 
ATOM   5350 C CG  . PHE C 3 110 ? 62.174  132.535 114.138 1.00 63.13  ?  109 PHE E CG  1 
ATOM   5351 C CD1 . PHE C 3 110 ? 61.624  132.851 115.369 1.00 63.13  ?  109 PHE E CD1 1 
ATOM   5352 C CD2 . PHE C 3 110 ? 62.431  133.558 113.241 1.00 63.13  ?  109 PHE E CD2 1 
ATOM   5353 C CE1 . PHE C 3 110 ? 61.335  134.162 115.698 1.00 63.13  ?  109 PHE E CE1 1 
ATOM   5354 C CE2 . PHE C 3 110 ? 62.145  134.870 113.565 1.00 63.13  ?  109 PHE E CE2 1 
ATOM   5355 C CZ  . PHE C 3 110 ? 61.596  135.172 114.795 1.00 63.13  ?  109 PHE E CZ  1 
ATOM   5356 N N   . TRP C 3 111 ? 59.781  131.516 111.687 1.00 64.04  ?  110 TRP E N   1 
ATOM   5357 C CA  . TRP C 3 111 ? 59.304  132.114 110.448 1.00 64.04  ?  110 TRP E CA  1 
ATOM   5358 C C   . TRP C 3 111 ? 59.319  133.630 110.579 1.00 64.04  ?  110 TRP E C   1 
ATOM   5359 O O   . TRP C 3 111 ? 58.795  134.179 111.554 1.00 64.04  ?  110 TRP E O   1 
ATOM   5360 C CB  . TRP C 3 111 ? 57.892  131.628 110.116 1.00 64.04  ?  110 TRP E CB  1 
ATOM   5361 C CG  . TRP C 3 111 ? 57.849  130.232 109.576 1.00 64.04  ?  110 TRP E CG  1 
ATOM   5362 C CD1 . TRP C 3 111 ? 58.178  129.086 110.239 1.00 64.04  ?  110 TRP E CD1 1 
ATOM   5363 C CD2 . TRP C 3 111 ? 57.445  129.833 108.261 1.00 64.04  ?  110 TRP E CD2 1 
ATOM   5364 N NE1 . TRP C 3 111 ? 58.009  127.998 109.416 1.00 64.04  ?  110 TRP E NE1 1 
ATOM   5365 C CE2 . TRP C 3 111 ? 57.559  128.431 108.196 1.00 64.04  ?  110 TRP E CE2 1 
ATOM   5366 C CE3 . TRP C 3 111 ? 57.000  130.527 107.131 1.00 64.04  ?  110 TRP E CE3 1 
ATOM   5367 C CZ2 . TRP C 3 111 ? 57.245  127.709 107.046 1.00 64.04  ?  110 TRP E CZ2 1 
ATOM   5368 C CZ3 . TRP C 3 111 ? 56.689  129.808 105.991 1.00 64.04  ?  110 TRP E CZ3 1 
ATOM   5369 C CH2 . TRP C 3 111 ? 56.813  128.414 105.957 1.00 64.04  ?  110 TRP E CH2 1 
ATOM   5370 N N   . GLY C 3 112 ? 59.916  134.300 109.598 1.00 65.20  ?  111 GLY E N   1 
ATOM   5371 C CA  . GLY C 3 112 ? 59.970  135.745 109.608 1.00 65.20  ?  111 GLY E CA  1 
ATOM   5372 C C   . GLY C 3 112 ? 58.624  136.372 109.295 1.00 65.20  ?  111 GLY E C   1 
ATOM   5373 O O   . GLY C 3 112 ? 57.666  135.717 108.884 1.00 65.20  ?  111 GLY E O   1 
ATOM   5374 N N   . GLN C 3 113 ? 58.559  137.690 109.500 1.00 67.31  ?  112 GLN E N   1 
ATOM   5375 C CA  . GLN C 3 113 ? 57.319  138.414 109.243 1.00 67.31  ?  112 GLN E CA  1 
ATOM   5376 C C   . GLN C 3 113 ? 56.995  138.461 107.755 1.00 67.31  ?  112 GLN E C   1 
ATOM   5377 O O   . GLN C 3 113 ? 55.817  138.488 107.380 1.00 67.31  ?  112 GLN E O   1 
ATOM   5378 C CB  . GLN C 3 113 ? 57.413  139.831 109.808 1.00 67.31  ?  112 GLN E CB  1 
ATOM   5379 C CG  . GLN C 3 113 ? 57.727  139.888 111.296 1.00 67.31  ?  112 GLN E CG  1 
ATOM   5380 C CD  . GLN C 3 113 ? 56.650  139.245 112.148 1.00 67.31  ?  112 GLN E CD  1 
ATOM   5381 O OE1 . GLN C 3 113 ? 55.554  138.952 111.669 1.00 67.31  ?  112 GLN E OE1 1 
ATOM   5382 N NE2 . GLN C 3 113 ? 56.958  139.021 113.420 1.00 67.31  ?  112 GLN E NE2 1 
ATOM   5383 N N   . GLY C 3 114 ? 58.014  138.473 106.900 1.00 67.52  ?  113 GLY E N   1 
ATOM   5384 C CA  . GLY C 3 114 ? 57.800  138.500 105.469 1.00 67.52  ?  113 GLY E CA  1 
ATOM   5385 C C   . GLY C 3 114 ? 57.446  139.885 104.962 1.00 67.52  ?  113 GLY E C   1 
ATOM   5386 O O   . GLY C 3 114 ? 57.267  140.843 105.715 1.00 67.52  ?  113 GLY E O   1 
ATOM   5387 N N   . THR C 3 115 ? 57.344  139.982 103.637 1.00 69.16  ?  114 THR E N   1 
ATOM   5388 C CA  . THR C 3 115 ? 57.010  141.233 102.971 1.00 69.16  ?  114 THR E CA  1 
ATOM   5389 C C   . THR C 3 115 ? 56.125  140.937 101.771 1.00 69.16  ?  114 THR E C   1 
ATOM   5390 O O   . THR C 3 115 ? 56.289  139.909 101.109 1.00 69.16  ?  114 THR E O   1 
ATOM   5391 C CB  . THR C 3 115 ? 58.271  141.987 102.523 1.00 69.16  ?  114 THR E CB  1 
ATOM   5392 O OG1 . THR C 3 115 ? 57.902  143.251 101.959 1.00 69.16  ?  114 THR E OG1 1 
ATOM   5393 C CG2 . THR C 3 115 ? 59.047  141.178 101.490 1.00 69.16  ?  114 THR E CG2 1 
ATOM   5394 N N   . THR C 3 116 ? 55.190  141.842 101.494 1.00 71.40  ?  115 THR E N   1 
ATOM   5395 C CA  . THR C 3 116 ? 54.235  141.663 100.407 1.00 71.40  ?  115 THR E CA  1 
ATOM   5396 C C   . THR C 3 116 ? 54.737  142.361 99.150  1.00 71.40  ?  115 THR E C   1 
ATOM   5397 O O   . THR C 3 116 ? 55.145  143.527 99.198  1.00 71.40  ?  115 THR E O   1 
ATOM   5398 C CB  . THR C 3 116 ? 52.858  142.204 100.798 1.00 71.40  ?  115 THR E CB  1 
ATOM   5399 O OG1 . THR C 3 116 ? 51.914  141.910 99.760  1.00 71.40  ?  115 THR E OG1 1 
ATOM   5400 C CG2 . THR C 3 116 ? 52.902  143.714 101.023 1.00 71.40  ?  115 THR E CG2 1 
ATOM   5401 N N   . LEU C 3 117 ? 54.708  141.644 98.027  1.00 70.94  ?  116 LEU E N   1 
ATOM   5402 C CA  . LEU C 3 117 ? 55.097  142.182 96.731  1.00 70.94  ?  116 LEU E CA  1 
ATOM   5403 C C   . LEU C 3 117 ? 53.954  141.931 95.762  1.00 70.94  ?  116 LEU E C   1 
ATOM   5404 O O   . LEU C 3 117 ? 53.589  140.775 95.518  1.00 70.94  ?  116 LEU E O   1 
ATOM   5405 C CB  . LEU C 3 117 ? 56.389  141.530 96.227  1.00 70.94  ?  116 LEU E CB  1 
ATOM   5406 C CG  . LEU C 3 117 ? 57.022  142.151 94.980  1.00 70.94  ?  116 LEU E CG  1 
ATOM   5407 C CD1 . LEU C 3 117 ? 57.640  143.501 95.309  1.00 70.94  ?  116 LEU E CD1 1 
ATOM   5408 C CD2 . LEU C 3 117 ? 58.060  141.214 94.383  1.00 70.94  ?  116 LEU E CD2 1 
ATOM   5409 N N   . THR C 3 118 ? 53.385  143.005 95.224  1.00 71.53  ?  117 THR E N   1 
ATOM   5410 C CA  . THR C 3 118 ? 52.253  142.931 94.315  1.00 71.53  ?  117 THR E CA  1 
ATOM   5411 C C   . THR C 3 118 ? 52.676  143.373 92.920  1.00 71.53  ?  117 THR E C   1 
ATOM   5412 O O   . THR C 3 118 ? 53.586  144.193 92.758  1.00 71.53  ?  117 THR E O   1 
ATOM   5413 C CB  . THR C 3 118 ? 51.094  143.805 94.807  1.00 71.53  ?  117 THR E CB  1 
ATOM   5414 O OG1 . THR C 3 118 ? 50.744  143.432 96.146  1.00 71.53  ?  117 THR E OG1 1 
ATOM   5415 C CG2 . THR C 3 118 ? 49.876  143.647 93.907  1.00 71.53  ?  117 THR E CG2 1 
ATOM   5416 N N   . VAL C 3 119 ? 52.008  142.814 91.915  1.00 72.91  ?  118 VAL E N   1 
ATOM   5417 C CA  . VAL C 3 119 ? 52.282  143.119 90.517  1.00 72.91  ?  118 VAL E CA  1 
ATOM   5418 C C   . VAL C 3 119 ? 51.107  143.901 89.950  1.00 72.91  ?  118 VAL E C   1 
ATOM   5419 O O   . VAL C 3 119 ? 49.953  143.711 90.352  1.00 72.91  ?  118 VAL E O   1 
ATOM   5420 C CB  . VAL C 3 119 ? 52.537  141.839 89.693  1.00 72.91  ?  118 VAL E CB  1 
ATOM   5421 C CG1 . VAL C 3 119 ? 52.801  142.189 88.233  1.00 72.91  ?  118 VAL E CG1 1 
ATOM   5422 C CG2 . VAL C 3 119 ? 53.698  141.045 90.288  1.00 72.91  ?  118 VAL E CG2 1 
ATOM   5423 N N   . SER C 3 120 ? 51.409  144.788 89.006  1.00 73.71  ?  119 SER E N   1 
ATOM   5424 C CA  . SER C 3 120 ? 50.389  145.614 88.370  1.00 73.71  ?  119 SER E CA  1 
ATOM   5425 C C   . SER C 3 120 ? 49.623  146.428 89.407  1.00 73.71  ?  119 SER E C   1 
ATOM   5426 O O   . SER C 3 120 ? 49.711  147.655 89.436  1.00 73.71  ?  119 SER E O   1 
ATOM   5427 C CB  . SER C 3 120 ? 49.421  144.745 87.563  1.00 73.71  ?  119 SER E CB  1 
ATOM   5428 O OG  . SER C 3 120 ? 48.442  145.540 86.916  1.00 73.71  ?  119 SER E OG  1 
ATOM   5429 N N   . ALA C 3 137 ? 56.884  117.383 88.898  1.00 70.84  ?  136 ALA E N   1 
ATOM   5430 C CA  . ALA C 3 137 ? 56.513  116.022 89.268  1.00 70.84  ?  136 ALA E CA  1 
ATOM   5431 C C   . ALA C 3 137 ? 56.881  115.728 90.719  1.00 70.84  ?  136 ALA E C   1 
ATOM   5432 O O   . ALA C 3 137 ? 56.907  114.571 91.139  1.00 70.84  ?  136 ALA E O   1 
ATOM   5433 C CB  . ALA C 3 137 ? 57.186  115.023 88.340  1.00 70.84  ?  136 ALA E CB  1 
ATOM   5434 N N   . ASP C 3 138 ? 57.165  116.781 91.483  1.00 68.63  ?  137 ASP E N   1 
ATOM   5435 C CA  . ASP C 3 138 ? 57.524  116.616 92.881  1.00 68.63  ?  137 ASP E CA  1 
ATOM   5436 C C   . ASP C 3 138 ? 56.337  116.076 93.676  1.00 68.63  ?  137 ASP E C   1 
ATOM   5437 O O   . ASP C 3 138 ? 55.209  115.977 93.183  1.00 68.63  ?  137 ASP E O   1 
ATOM   5438 C CB  . ASP C 3 138 ? 57.999  117.944 93.471  1.00 68.63  ?  137 ASP E CB  1 
ATOM   5439 C CG  . ASP C 3 138 ? 56.937  119.025 93.403  1.00 68.63  ?  137 ASP E CG  1 
ATOM   5440 O OD1 . ASP C 3 138 ? 55.958  118.949 94.175  1.00 68.63  ?  137 ASP E OD1 1 
ATOM   5441 O OD2 . ASP C 3 138 ? 57.082  119.951 92.578  1.00 68.63  ?  137 ASP E OD2 1 
ATOM   5442 N N   . ILE C 3 139 ? 56.606  115.721 94.935  1.00 66.74  ?  138 ILE E N   1 
ATOM   5443 C CA  . ILE C 3 139 ? 55.554  115.202 95.798  1.00 66.74  ?  138 ILE E CA  1 
ATOM   5444 C C   . ILE C 3 139 ? 54.518  116.290 96.042  1.00 66.74  ?  138 ILE E C   1 
ATOM   5445 O O   . ILE C 3 139 ? 54.853  117.450 96.312  1.00 66.74  ?  138 ILE E O   1 
ATOM   5446 C CB  . ILE C 3 139 ? 56.147  114.690 97.122  1.00 66.74  ?  138 ILE E CB  1 
ATOM   5447 C CG1 . ILE C 3 139 ? 57.182  113.594 96.852  1.00 66.74  ?  138 ILE E CG1 1 
ATOM   5448 C CG2 . ILE C 3 139 ? 55.040  114.168 98.034  1.00 66.74  ?  138 ILE E CG2 1 
ATOM   5449 C CD1 . ILE C 3 139 ? 57.927  113.132 98.088  1.00 66.74  ?  138 ILE E CD1 1 
ATOM   5450 N N   . VAL C 3 140 ? 53.245  115.914 95.947  1.00 68.00  ?  139 VAL E N   1 
ATOM   5451 C CA  . VAL C 3 140 ? 52.127  116.831 96.139  1.00 68.00  ?  139 VAL E CA  1 
ATOM   5452 C C   . VAL C 3 140 ? 51.388  116.436 97.408  1.00 68.00  ?  139 VAL E C   1 
ATOM   5453 O O   . VAL C 3 140 ? 51.177  115.246 97.673  1.00 68.00  ?  139 VAL E O   1 
ATOM   5454 C CB  . VAL C 3 140 ? 51.177  116.828 94.924  1.00 68.00  ?  139 VAL E CB  1 
ATOM   5455 C CG1 . VAL C 3 140 ? 50.587  115.440 94.700  1.00 68.00  ?  139 VAL E CG1 1 
ATOM   5456 C CG2 . VAL C 3 140 ? 50.073  117.860 95.109  1.00 68.00  ?  139 VAL E CG2 1 
ATOM   5457 N N   . MET C 3 141 ? 50.997  117.437 98.192  1.00 69.51  ?  140 MET E N   1 
ATOM   5458 C CA  . MET C 3 141 ? 50.267  117.237 99.438  1.00 69.51  ?  140 MET E CA  1 
ATOM   5459 C C   . MET C 3 141 ? 48.838  117.725 99.246  1.00 69.51  ?  140 MET E C   1 
ATOM   5460 O O   . MET C 3 141 ? 48.619  118.885 98.881  1.00 69.51  ?  140 MET E O   1 
ATOM   5461 C CB  . MET C 3 141 ? 50.941  117.981 100.591 1.00 69.51  ?  140 MET E CB  1 
ATOM   5462 C CG  . MET C 3 141 ? 52.421  117.669 100.752 1.00 69.51  ?  140 MET E CG  1 
ATOM   5463 S SD  . MET C 3 141 ? 52.754  115.920 101.038 1.00 69.51  ?  140 MET E SD  1 
ATOM   5464 C CE  . MET C 3 141 ? 51.931  115.666 102.608 1.00 69.51  ?  140 MET E CE  1 
ATOM   5465 N N   . THR C 3 142 ? 47.873  116.842 99.492  1.00 72.96  ?  141 THR E N   1 
ATOM   5466 C CA  . THR C 3 142 ? 46.456  117.146 99.325  1.00 72.96  ?  141 THR E CA  1 
ATOM   5467 C C   . THR C 3 142 ? 45.734  116.857 100.633 1.00 72.96  ?  141 THR E C   1 
ATOM   5468 O O   . THR C 3 142 ? 45.828  115.745 101.165 1.00 72.96  ?  141 THR E O   1 
ATOM   5469 C CB  . THR C 3 142 ? 45.847  116.327 98.185  1.00 72.96  ?  141 THR E CB  1 
ATOM   5470 O OG1 . THR C 3 142 ? 46.007  114.929 98.455  1.00 72.96  ?  141 THR E OG1 1 
ATOM   5471 C CG2 . THR C 3 142 ? 46.520  116.667 96.863  1.00 72.96  ?  141 THR E CG2 1 
ATOM   5472 N N   . GLN C 3 143 ? 45.016  117.853 101.144 1.00 75.05  ?  142 GLN E N   1 
ATOM   5473 C CA  . GLN C 3 143 ? 44.247  117.720 102.372 1.00 75.05  ?  142 GLN E CA  1 
ATOM   5474 C C   . GLN C 3 143 ? 42.777  117.502 102.041 1.00 75.05  ?  142 GLN E C   1 
ATOM   5475 O O   . GLN C 3 143 ? 42.275  118.007 101.032 1.00 75.05  ?  142 GLN E O   1 
ATOM   5476 C CB  . GLN C 3 143 ? 44.408  118.959 103.254 1.00 75.05  ?  142 GLN E CB  1 
ATOM   5477 C CG  . GLN C 3 143 ? 45.844  119.229 103.681 1.00 75.05  ?  142 GLN E CG  1 
ATOM   5478 C CD  . GLN C 3 143 ? 45.979  120.463 104.554 1.00 75.05  ?  142 GLN E CD  1 
ATOM   5479 O OE1 . GLN C 3 143 ? 46.884  121.274 104.362 1.00 75.05  ?  142 GLN E OE1 1 
ATOM   5480 N NE2 . GLN C 3 143 ? 45.082  120.607 105.524 1.00 75.05  ?  142 GLN E NE2 1 
ATOM   5481 N N   . ALA C 3 144 ? 42.090  116.745 102.898 1.00 79.89  ?  143 ALA E N   1 
ATOM   5482 C CA  . ALA C 3 144 ? 40.691  116.418 102.641 1.00 79.89  ?  143 ALA E CA  1 
ATOM   5483 C C   . ALA C 3 144 ? 39.794  117.635 102.837 1.00 79.89  ?  143 ALA E C   1 
ATOM   5484 O O   . ALA C 3 144 ? 39.075  118.043 101.917 1.00 79.89  ?  143 ALA E O   1 
ATOM   5485 C CB  . ALA C 3 144 ? 40.248  115.272 103.549 1.00 79.89  ?  143 ALA E CB  1 
ATOM   5486 N N   . THR C 3 145 ? 39.823  118.228 104.027 1.00 80.63  ?  144 THR E N   1 
ATOM   5487 C CA  . THR C 3 145 ? 38.971  119.356 104.371 1.00 80.63  ?  144 THR E CA  1 
ATOM   5488 C C   . THR C 3 145 ? 39.808  120.620 104.506 1.00 80.63  ?  144 THR E C   1 
ATOM   5489 O O   . THR C 3 145 ? 40.930  120.583 105.022 1.00 80.63  ?  144 THR E O   1 
ATOM   5490 C CB  . THR C 3 145 ? 38.214  119.095 105.677 1.00 80.63  ?  144 THR E CB  1 
ATOM   5491 O OG1 . THR C 3 145 ? 37.459  117.882 105.563 1.00 80.63  ?  144 THR E OG1 1 
ATOM   5492 C CG2 . THR C 3 145 ? 37.269  120.248 105.990 1.00 80.63  ?  144 THR E CG2 1 
ATOM   5493 N N   . SER C 3 146 ? 39.255  121.740 104.038 1.00 80.60  ?  145 SER E N   1 
ATOM   5494 C CA  . SER C 3 146 ? 39.930  123.028 104.113 1.00 80.60  ?  145 SER E CA  1 
ATOM   5495 C C   . SER C 3 146 ? 39.468  123.882 105.285 1.00 80.60  ?  145 SER E C   1 
ATOM   5496 O O   . SER C 3 146 ? 40.212  124.771 105.713 1.00 80.60  ?  145 SER E O   1 
ATOM   5497 C CB  . SER C 3 146 ? 39.719  123.813 102.812 1.00 80.60  ?  145 SER E CB  1 
ATOM   5498 O OG  . SER C 3 146 ? 40.366  125.072 102.866 1.00 80.60  ?  145 SER E OG  1 
ATOM   5499 N N   . SER C 3 147 ? 38.267  123.640 105.807 1.00 80.90  ?  146 SER E N   1 
ATOM   5500 C CA  . SER C 3 147 ? 37.752  124.393 106.941 1.00 80.90  ?  146 SER E CA  1 
ATOM   5501 C C   . SER C 3 147 ? 36.922  123.463 107.811 1.00 80.90  ?  146 SER E C   1 
ATOM   5502 O O   . SER C 3 147 ? 36.069  122.727 107.307 1.00 80.90  ?  146 SER E O   1 
ATOM   5503 C CB  . SER C 3 147 ? 36.907  125.587 106.483 1.00 80.90  ?  146 SER E CB  1 
ATOM   5504 O OG  . SER C 3 147 ? 37.671  126.479 105.690 1.00 80.90  ?  146 SER E OG  1 
ATOM   5505 N N   . VAL C 3 148 ? 37.177  123.503 109.120 1.00 80.96  ?  147 VAL E N   1 
ATOM   5506 C CA  . VAL C 3 148 ? 36.486  122.662 110.085 1.00 80.96  ?  147 VAL E CA  1 
ATOM   5507 C C   . VAL C 3 148 ? 36.000  123.549 111.225 1.00 80.96  ?  147 VAL E C   1 
ATOM   5508 O O   . VAL C 3 148 ? 36.814  124.052 112.004 1.00 80.96  ?  147 VAL E O   1 
ATOM   5509 C CB  . VAL C 3 148 ? 37.385  121.540 110.635 1.00 80.96  ?  147 VAL E CB  1 
ATOM   5510 C CG1 . VAL C 3 148 ? 36.664  120.775 111.739 1.00 80.96  ?  147 VAL E CG1 1 
ATOM   5511 C CG2 . VAL C 3 148 ? 37.820  120.604 109.511 1.00 80.96  ?  147 VAL E CG2 1 
ATOM   5512 N N   . PRO C 3 149 ? 34.694  123.777 111.372 1.00 81.52  ?  148 PRO E N   1 
ATOM   5513 C CA  . PRO C 3 149 ? 34.217  124.592 112.495 1.00 81.52  ?  148 PRO E CA  1 
ATOM   5514 C C   . PRO C 3 149 ? 34.281  123.829 113.808 1.00 81.52  ?  148 PRO E C   1 
ATOM   5515 O O   . PRO C 3 149 ? 33.931  122.649 113.886 1.00 81.52  ?  148 PRO E O   1 
ATOM   5516 C CB  . PRO C 3 149 ? 32.769  124.914 112.106 1.00 81.52  ?  148 PRO E CB  1 
ATOM   5517 C CG  . PRO C 3 149 ? 32.356  123.773 111.248 1.00 81.52  ?  148 PRO E CG  1 
ATOM   5518 C CD  . PRO C 3 149 ? 33.588  123.349 110.496 1.00 81.52  ?  148 PRO E CD  1 
ATOM   5519 N N   . VAL C 3 150 ? 34.738  124.522 114.851 1.00 81.03  ?  149 VAL E N   1 
ATOM   5520 C CA  . VAL C 3 150 ? 34.884  123.921 116.171 1.00 81.03  ?  149 VAL E CA  1 
ATOM   5521 C C   . VAL C 3 150 ? 35.002  125.045 117.187 1.00 81.03  ?  149 VAL E C   1 
ATOM   5522 O O   . VAL C 3 150 ? 35.498  126.131 116.878 1.00 81.03  ?  149 VAL E O   1 
ATOM   5523 C CB  . VAL C 3 150 ? 36.105  122.967 116.219 1.00 81.03  ?  149 VAL E CB  1 
ATOM   5524 C CG1 . VAL C 3 150 ? 37.381  123.703 115.824 1.00 81.03  ?  149 VAL E CG1 1 
ATOM   5525 C CG2 . VAL C 3 150 ? 36.244  122.344 117.601 1.00 81.03  ?  149 VAL E CG2 1 
ATOM   5526 N N   . THR C 3 151 ? 34.544  124.780 118.405 1.00 81.72  ?  150 THR E N   1 
ATOM   5527 C CA  . THR C 3 151 ? 34.564  125.733 119.500 1.00 81.72  ?  150 THR E CA  1 
ATOM   5528 C C   . THR C 3 151 ? 35.570  125.295 120.557 1.00 81.72  ?  150 THR E C   1 
ATOM   5529 O O   . THR C 3 151 ? 35.992  124.133 120.580 1.00 81.72  ?  150 THR E O   1 
ATOM   5530 C CB  . THR C 3 151 ? 33.174  125.867 120.139 1.00 81.72  ?  150 THR E CB  1 
ATOM   5531 O OG1 . THR C 3 151 ? 32.746  124.591 120.632 1.00 81.72  ?  150 THR E OG1 1 
ATOM   5532 C CG2 . THR C 3 151 ? 32.164  126.381 119.123 1.00 81.72  ?  150 THR E CG2 1 
ATOM   5533 N N   . PRO C 3 152 ? 35.979  126.200 121.446 1.00 81.42  ?  151 PRO E N   1 
ATOM   5534 C CA  . PRO C 3 152 ? 36.937  125.818 122.490 1.00 81.42  ?  151 PRO E CA  1 
ATOM   5535 C C   . PRO C 3 152 ? 36.395  124.694 123.361 1.00 81.42  ?  151 PRO E C   1 
ATOM   5536 O O   . PRO C 3 152 ? 35.195  124.613 123.630 1.00 81.42  ?  151 PRO E O   1 
ATOM   5537 C CB  . PRO C 3 152 ? 37.126  127.112 123.291 1.00 81.42  ?  151 PRO E CB  1 
ATOM   5538 C CG  . PRO C 3 152 ? 36.734  128.204 122.358 1.00 81.42  ?  151 PRO E CG  1 
ATOM   5539 C CD  . PRO C 3 152 ? 35.647  127.634 121.501 1.00 81.42  ?  151 PRO E CD  1 
ATOM   5540 N N   . GLY C 3 153 ? 37.302  123.817 123.802 1.00 79.63  ?  152 GLY E N   1 
ATOM   5541 C CA  . GLY C 3 153 ? 36.979  122.696 124.658 1.00 79.63  ?  152 GLY E CA  1 
ATOM   5542 C C   . GLY C 3 153 ? 37.013  121.356 123.948 1.00 79.63  ?  152 GLY E C   1 
ATOM   5543 O O   . GLY C 3 153 ? 37.367  120.345 124.568 1.00 79.63  ?  152 GLY E O   1 
ATOM   5544 N N   . GLU C 3 154 ? 36.657  121.327 122.668 1.00 80.90  ?  153 GLU E N   1 
ATOM   5545 C CA  . GLU C 3 154 ? 36.638  120.093 121.900 1.00 80.90  ?  153 GLU E CA  1 
ATOM   5546 C C   . GLU C 3 154 ? 37.999  119.844 121.254 1.00 80.90  ?  153 GLU E C   1 
ATOM   5547 O O   . GLU C 3 154 ? 38.867  120.718 121.206 1.00 80.90  ?  153 GLU E O   1 
ATOM   5548 C CB  . GLU C 3 154 ? 35.544  120.142 120.832 1.00 80.90  ?  153 GLU E CB  1 
ATOM   5549 C CG  . GLU C 3 154 ? 34.123  120.118 121.382 1.00 80.90  ?  153 GLU E CG  1 
ATOM   5550 C CD  . GLU C 3 154 ? 33.750  121.395 122.111 1.00 80.90  ?  153 GLU E CD  1 
ATOM   5551 O OE1 . GLU C 3 154 ? 34.600  122.307 122.188 1.00 80.90  ?  153 GLU E OE1 1 
ATOM   5552 O OE2 . GLU C 3 154 ? 32.607  121.486 122.606 1.00 80.90  ?  153 GLU E OE2 1 
ATOM   5553 N N   . SER C 3 155 ? 38.176  118.626 120.752 1.00 77.89  ?  154 SER E N   1 
ATOM   5554 C CA  . SER C 3 155 ? 39.403  118.218 120.087 1.00 77.89  ?  154 SER E CA  1 
ATOM   5555 C C   . SER C 3 155 ? 39.209  118.233 118.576 1.00 77.89  ?  154 SER E C   1 
ATOM   5556 O O   . SER C 3 155 ? 38.093  118.083 118.072 1.00 77.89  ?  154 SER E O   1 
ATOM   5557 C CB  . SER C 3 155 ? 39.832  116.822 120.542 1.00 77.89  ?  154 SER E CB  1 
ATOM   5558 O OG  . SER C 3 155 ? 41.035  116.425 119.907 1.00 77.89  ?  154 SER E OG  1 
ATOM   5559 N N   . VAL C 3 156 ? 40.313  118.415 117.855 1.00 77.22  ?  155 VAL E N   1 
ATOM   5560 C CA  . VAL C 3 156 ? 40.297  118.481 116.399 1.00 77.22  ?  155 VAL E CA  1 
ATOM   5561 C C   . VAL C 3 156 ? 41.250  117.429 115.852 1.00 77.22  ?  155 VAL E C   1 
ATOM   5562 O O   . VAL C 3 156 ? 42.267  117.103 116.471 1.00 77.22  ?  155 VAL E O   1 
ATOM   5563 C CB  . VAL C 3 156 ? 40.683  119.887 115.886 1.00 77.22  ?  155 VAL E CB  1 
ATOM   5564 C CG1 . VAL C 3 156 ? 40.635  119.934 114.364 1.00 77.22  ?  155 VAL E CG1 1 
ATOM   5565 C CG2 . VAL C 3 156 ? 39.766  120.944 116.487 1.00 77.22  ?  155 VAL E CG2 1 
ATOM   5566 N N   . SER C 3 157 ? 40.911  116.895 114.677 1.00 75.22  ?  156 SER E N   1 
ATOM   5567 C CA  . SER C 3 157 ? 41.715  115.863 114.014 1.00 75.22  ?  156 SER E CA  1 
ATOM   5568 C C   . SER C 3 157 ? 41.772  116.205 112.525 1.00 75.22  ?  156 SER E C   1 
ATOM   5569 O O   . SER C 3 157 ? 40.869  115.854 111.761 1.00 75.22  ?  156 SER E O   1 
ATOM   5570 C CB  . SER C 3 157 ? 41.137  114.475 114.252 1.00 75.22  ?  156 SER E CB  1 
ATOM   5571 O OG  . SER C 3 157 ? 41.103  114.167 115.635 1.00 75.22  ?  156 SER E OG  1 
ATOM   5572 N N   . ILE C 3 158 ? 42.838  116.891 112.123 1.00 74.17  ?  157 ILE E N   1 
ATOM   5573 C CA  . ILE C 3 158 ? 43.028  117.257 110.724 1.00 74.17  ?  157 ILE E CA  1 
ATOM   5574 C C   . ILE C 3 158 ? 43.742  116.119 110.009 1.00 74.17  ?  157 ILE E C   1 
ATOM   5575 O O   . ILE C 3 158 ? 44.723  115.566 110.521 1.00 74.17  ?  157 ILE E O   1 
ATOM   5576 C CB  . ILE C 3 158 ? 43.818  118.570 110.606 1.00 74.17  ?  157 ILE E CB  1 
ATOM   5577 C CG1 . ILE C 3 158 ? 43.064  119.707 111.304 1.00 74.17  ?  157 ILE E CG1 1 
ATOM   5578 C CG2 . ILE C 3 158 ? 44.067  118.909 109.140 1.00 74.17  ?  157 ILE E CG2 1 
ATOM   5579 C CD1 . ILE C 3 158 ? 43.840  121.007 111.380 1.00 74.17  ?  157 ILE E CD1 1 
ATOM   5580 N N   . SER C 3 159 ? 43.255  115.767 108.824 1.00 75.30  ?  158 SER E N   1 
ATOM   5581 C CA  . SER C 3 159 ? 43.826  114.696 108.023 1.00 75.30  ?  158 SER E CA  1 
ATOM   5582 C C   . SER C 3 159 ? 44.657  115.270 106.880 1.00 75.30  ?  158 SER E C   1 
ATOM   5583 O O   . SER C 3 159 ? 44.465  116.410 106.449 1.00 75.30  ?  158 SER E O   1 
ATOM   5584 C CB  . SER C 3 159 ? 42.724  113.792 107.465 1.00 75.30  ?  158 SER E CB  1 
ATOM   5585 O OG  . SER C 3 159 ? 41.833  114.524 106.641 1.00 75.30  ?  158 SER E OG  1 
ATOM   5586 N N   . CYS C 3 160 ? 45.592  114.457 106.392 1.00 72.93  ?  159 CYS E N   1 
ATOM   5587 C CA  . CYS C 3 160 ? 46.456  114.857 105.292 1.00 72.93  ?  159 CYS E CA  1 
ATOM   5588 C C   . CYS C 3 160 ? 46.828  113.628 104.476 1.00 72.93  ?  159 CYS E C   1 
ATOM   5589 O O   . CYS C 3 160 ? 47.146  112.575 105.037 1.00 72.93  ?  159 CYS E O   1 
ATOM   5590 C CB  . CYS C 3 160 ? 47.723  115.553 105.803 1.00 72.93  ?  159 CYS E CB  1 
ATOM   5591 S SG  . CYS C 3 160 ? 48.938  115.912 104.515 1.00 72.93  ?  159 CYS E SG  1 
ATOM   5592 N N   . ARG C 3 161 ? 46.791  113.774 103.154 1.00 72.93  ?  160 ARG E N   1 
ATOM   5593 C CA  . ARG C 3 161 ? 47.112  112.701 102.227 1.00 72.93  ?  160 ARG E CA  1 
ATOM   5594 C C   . ARG C 3 161 ? 48.250  113.133 101.313 1.00 72.93  ?  160 ARG E C   1 
ATOM   5595 O O   . ARG C 3 161 ? 48.400  114.317 100.998 1.00 72.93  ?  160 ARG E O   1 
ATOM   5596 C CB  . ARG C 3 161 ? 45.888  112.310 101.387 1.00 72.93  ?  160 ARG E CB  1 
ATOM   5597 C CG  . ARG C 3 161 ? 46.125  111.137 100.447 1.00 72.93  ?  160 ARG E CG  1 
ATOM   5598 C CD  . ARG C 3 161 ? 44.861  110.754 99.690  1.00 72.93  ?  160 ARG E CD  1 
ATOM   5599 N NE  . ARG C 3 161 ? 44.398  111.820 98.801  1.00 72.93  ?  160 ARG E NE  1 
ATOM   5600 C CZ  . ARG C 3 161 ? 43.535  112.773 99.143  1.00 72.93  ?  160 ARG E CZ  1 
ATOM   5601 N NH1 . ARG C 3 161 ? 43.182  113.692 98.256  1.00 72.93  1  160 ARG E NH1 1 
ATOM   5602 N NH2 . ARG C 3 161 ? 43.021  112.815 100.367 1.00 72.93  ?  160 ARG E NH2 1 
ATOM   5603 N N   . SER C 3 162 ? 49.052  112.158 100.890 1.00 69.02  ?  161 SER E N   1 
ATOM   5604 C CA  . SER C 3 162 ? 50.183  112.398 100.008 1.00 69.02  ?  161 SER E CA  1 
ATOM   5605 C C   . SER C 3 162 ? 50.195  111.356 98.899  1.00 69.02  ?  161 SER E C   1 
ATOM   5606 O O   . SER C 3 162 ? 49.692  110.242 99.066  1.00 69.02  ?  161 SER E O   1 
ATOM   5607 C CB  . SER C 3 162 ? 51.513  112.359 100.775 1.00 69.02  ?  161 SER E CB  1 
ATOM   5608 O OG  . SER C 3 162 ? 51.700  111.105 101.407 1.00 69.02  ?  161 SER E OG  1 
ATOM   5609 N N   . SER C 3 163 ? 50.777  111.732 97.761  1.00 67.38  ?  162 SER E N   1 
ATOM   5610 C CA  . SER C 3 163 ? 50.862  110.838 96.614  1.00 67.38  ?  162 SER E CA  1 
ATOM   5611 C C   . SER C 3 163 ? 52.060  109.900 96.677  1.00 67.38  ?  162 SER E C   1 
ATOM   5612 O O   . SER C 3 163 ? 52.059  108.873 95.989  1.00 67.38  ?  162 SER E O   1 
ATOM   5613 C CB  . SER C 3 163 ? 50.930  111.651 95.317  1.00 67.38  ?  162 SER E CB  1 
ATOM   5614 O OG  . SER C 3 163 ? 52.062  112.503 95.307  1.00 67.38  ?  162 SER E OG  1 
ATOM   5615 N N   . LYS C 3 164 ? 53.072  110.225 97.478  1.00 66.10  ?  163 LYS E N   1 
ATOM   5616 C CA  . LYS C 3 164 ? 54.263  109.400 97.620  1.00 66.10  ?  163 LYS E CA  1 
ATOM   5617 C C   . LYS C 3 164 ? 54.563  109.199 99.097  1.00 66.10  ?  163 LYS E C   1 
ATOM   5618 O O   . LYS C 3 164 ? 54.451  110.135 99.895  1.00 66.10  ?  163 LYS E O   1 
ATOM   5619 C CB  . LYS C 3 164 ? 55.470  110.038 96.920  1.00 66.10  ?  163 LYS E CB  1 
ATOM   5620 C CG  . LYS C 3 164 ? 56.739  109.201 96.982  1.00 66.10  ?  163 LYS E CG  1 
ATOM   5621 C CD  . LYS C 3 164 ? 57.877  109.862 96.221  1.00 66.10  ?  163 LYS E CD  1 
ATOM   5622 C CE  . LYS C 3 164 ? 59.150  109.033 96.295  1.00 66.10  ?  163 LYS E CE  1 
ATOM   5623 N NZ  . LYS C 3 164 ? 60.275  109.668 95.553  1.00 66.10  1  163 LYS E NZ  1 
ATOM   5624 N N   . SER C 3 165 ? 54.944  107.976 99.455  1.00 66.27  ?  164 SER E N   1 
ATOM   5625 C CA  . SER C 3 165 ? 55.257  107.658 100.843 1.00 66.27  ?  164 SER E CA  1 
ATOM   5626 C C   . SER C 3 165 ? 56.490  108.437 101.286 1.00 66.27  ?  164 SER E C   1 
ATOM   5627 O O   . SER C 3 165 ? 57.578  108.263 100.727 1.00 66.27  ?  164 SER E O   1 
ATOM   5628 C CB  . SER C 3 165 ? 55.484  106.157 101.001 1.00 66.27  ?  164 SER E CB  1 
ATOM   5629 O OG  . SER C 3 165 ? 55.788  105.827 102.345 1.00 66.27  ?  164 SER E OG  1 
ATOM   5630 N N   . LEU C 3 166 ? 56.319  109.294 102.290 1.00 65.72  ?  165 LEU E N   1 
ATOM   5631 C CA  . LEU C 3 166 ? 57.418  110.095 102.815 1.00 65.72  ?  165 LEU E CA  1 
ATOM   5632 C C   . LEU C 3 166 ? 58.346  109.303 103.727 1.00 65.72  ?  165 LEU E C   1 
ATOM   5633 O O   . LEU C 3 166 ? 59.362  109.848 104.171 1.00 65.72  ?  165 LEU E O   1 
ATOM   5634 C CB  . LEU C 3 166 ? 56.867  111.306 103.573 1.00 65.72  ?  165 LEU E CB  1 
ATOM   5635 C CG  . LEU C 3 166 ? 55.904  112.202 102.791 1.00 65.72  ?  165 LEU E CG  1 
ATOM   5636 C CD1 . LEU C 3 166 ? 55.440  113.367 103.650 1.00 65.72  ?  165 LEU E CD1 1 
ATOM   5637 C CD2 . LEU C 3 166 ? 56.549  112.706 101.508 1.00 65.72  ?  165 LEU E CD2 1 
ATOM   5638 N N   . LEU C 3 167 ? 58.029  108.043 104.015 1.00 62.76  ?  166 LEU E N   1 
ATOM   5639 C CA  . LEU C 3 167 ? 58.861  107.212 104.882 1.00 62.76  ?  166 LEU E CA  1 
ATOM   5640 C C   . LEU C 3 167 ? 60.109  106.796 104.115 1.00 62.76  ?  166 LEU E C   1 
ATOM   5641 O O   . LEU C 3 167 ? 60.071  105.886 103.284 1.00 62.76  ?  166 LEU E O   1 
ATOM   5642 C CB  . LEU C 3 167 ? 58.077  105.996 105.362 1.00 62.76  ?  166 LEU E CB  1 
ATOM   5643 C CG  . LEU C 3 167 ? 58.828  105.024 106.275 1.00 62.76  ?  166 LEU E CG  1 
ATOM   5644 C CD1 . LEU C 3 167 ? 59.272  105.714 107.556 1.00 62.76  ?  166 LEU E CD1 1 
ATOM   5645 C CD2 . LEU C 3 167 ? 57.965  103.812 106.588 1.00 62.76  ?  166 LEU E CD2 1 
ATOM   5646 N N   . HIS C 3 168 ? 61.225  107.464 104.392 1.00 61.86  ?  167 HIS E N   1 
ATOM   5647 C CA  . HIS C 3 168 ? 62.481  107.153 103.731 1.00 61.86  ?  167 HIS E CA  1 
ATOM   5648 C C   . HIS C 3 168 ? 63.106  105.901 104.345 1.00 61.86  ?  167 HIS E C   1 
ATOM   5649 O O   . HIS C 3 168 ? 62.727  105.448 105.428 1.00 61.86  ?  167 HIS E O   1 
ATOM   5650 C CB  . HIS C 3 168 ? 63.440  108.340 103.831 1.00 61.86  ?  167 HIS E CB  1 
ATOM   5651 C CG  . HIS C 3 168 ? 64.641  108.226 102.945 1.00 61.86  ?  167 HIS E CG  1 
ATOM   5652 N ND1 . HIS C 3 168 ? 64.547  108.143 101.572 1.00 61.86  ?  167 HIS E ND1 1 
ATOM   5653 C CD2 . HIS C 3 168 ? 65.962  108.182 103.235 1.00 61.86  ?  167 HIS E CD2 1 
ATOM   5654 C CE1 . HIS C 3 168 ? 65.759  108.053 101.055 1.00 61.86  ?  167 HIS E CE1 1 
ATOM   5655 N NE2 . HIS C 3 168 ? 66.636  108.073 102.043 1.00 61.86  ?  167 HIS E NE2 1 
ATOM   5656 N N   . SER C 3 169 ? 64.081  105.335 103.629 1.00 61.64  ?  168 SER E N   1 
ATOM   5657 C CA  . SER C 3 169 ? 64.744  104.124 104.098 1.00 61.64  ?  168 SER E CA  1 
ATOM   5658 C C   . SER C 3 169 ? 65.366  104.299 105.477 1.00 61.64  ?  168 SER E C   1 
ATOM   5659 O O   . SER C 3 169 ? 65.566  103.305 106.184 1.00 61.64  ?  168 SER E O   1 
ATOM   5660 C CB  . SER C 3 169 ? 65.820  103.697 103.097 1.00 61.64  ?  168 SER E CB  1 
ATOM   5661 O OG  . SER C 3 169 ? 66.799  104.709 102.939 1.00 61.64  ?  168 SER E OG  1 
ATOM   5662 N N   . ASN C 3 170 ? 65.675  105.534 105.877 1.00 61.23  ?  169 ASN E N   1 
ATOM   5663 C CA  . ASN C 3 170 ? 66.267  105.772 107.187 1.00 61.23  ?  169 ASN E CA  1 
ATOM   5664 C C   . ASN C 3 170 ? 65.241  105.733 108.312 1.00 61.23  ?  169 ASN E C   1 
ATOM   5665 O O   . ASN C 3 170 ? 65.629  105.632 109.481 1.00 61.23  ?  169 ASN E O   1 
ATOM   5666 C CB  . ASN C 3 170 ? 66.992  107.121 107.200 1.00 61.23  ?  169 ASN E CB  1 
ATOM   5667 C CG  . ASN C 3 170 ? 66.085  108.278 106.819 1.00 61.23  ?  169 ASN E CG  1 
ATOM   5668 O OD1 . ASN C 3 170 ? 64.863  108.191 106.937 1.00 61.23  ?  169 ASN E OD1 1 
ATOM   5669 N ND2 . ASN C 3 170 ? 66.684  109.369 106.358 1.00 61.23  ?  169 ASN E ND2 1 
ATOM   5670 N N   . GLY C 3 171 ? 63.951  105.811 107.991 1.00 61.32  ?  170 GLY E N   1 
ATOM   5671 C CA  . GLY C 3 171 ? 62.902  105.751 108.986 1.00 61.32  ?  170 GLY E CA  1 
ATOM   5672 C C   . GLY C 3 171 ? 62.401  107.092 109.475 1.00 61.32  ?  170 GLY E C   1 
ATOM   5673 O O   . GLY C 3 171 ? 61.524  107.123 110.347 1.00 61.32  ?  170 GLY E O   1 
ATOM   5674 N N   . ASN C 3 172 ? 62.922  108.196 108.947 1.00 61.34  ?  171 ASN E N   1 
ATOM   5675 C CA  . ASN C 3 172 ? 62.494  109.519 109.379 1.00 61.34  ?  171 ASN E CA  1 
ATOM   5676 C C   . ASN C 3 172 ? 61.247  109.951 108.619 1.00 61.34  ?  171 ASN E C   1 
ATOM   5677 O O   . ASN C 3 172 ? 61.157  109.791 107.399 1.00 61.34  ?  171 ASN E O   1 
ATOM   5678 C CB  . ASN C 3 172 ? 63.614  110.537 109.166 1.00 61.34  ?  171 ASN E CB  1 
ATOM   5679 C CG  . ASN C 3 172 ? 64.854  110.217 109.978 1.00 61.34  ?  171 ASN E CG  1 
ATOM   5680 O OD1 . ASN C 3 172 ? 65.748  109.509 109.515 1.00 61.34  ?  171 ASN E OD1 1 
ATOM   5681 N ND2 . ASN C 3 172 ? 64.914  110.740 111.197 1.00 61.34  ?  171 ASN E ND2 1 
ATOM   5682 N N   . THR C 3 173 ? 60.282  110.502 109.353 1.00 63.22  ?  172 THR E N   1 
ATOM   5683 C CA  . THR C 3 173 ? 59.028  110.978 108.772 1.00 63.22  ?  172 THR E CA  1 
ATOM   5684 C C   . THR C 3 173 ? 59.205  112.445 108.398 1.00 63.22  ?  172 THR E C   1 
ATOM   5685 O O   . THR C 3 173 ? 59.121  113.331 109.252 1.00 63.22  ?  172 THR E O   1 
ATOM   5686 C CB  . THR C 3 173 ? 57.872  110.787 109.748 1.00 63.22  ?  172 THR E CB  1 
ATOM   5687 O OG1 . THR C 3 173 ? 57.765  109.403 110.103 1.00 63.22  ?  172 THR E OG1 1 
ATOM   5688 C CG2 . THR C 3 173 ? 56.561  111.251 109.126 1.00 63.22  ?  172 THR E CG2 1 
ATOM   5689 N N   . TYR C 3 174 ? 59.451  112.702 107.113 1.00 61.87  ?  173 TYR E N   1 
ATOM   5690 C CA  . TYR C 3 174 ? 59.674  114.061 106.616 1.00 61.87  ?  173 TYR E CA  1 
ATOM   5691 C C   . TYR C 3 174 ? 58.326  114.756 106.420 1.00 61.87  ?  173 TYR E C   1 
ATOM   5692 O O   . TYR C 3 174 ? 57.823  114.930 105.308 1.00 61.87  ?  173 TYR E O   1 
ATOM   5693 C CB  . TYR C 3 174 ? 60.482  114.027 105.327 1.00 61.87  ?  173 TYR E CB  1 
ATOM   5694 C CG  . TYR C 3 174 ? 61.839  113.378 105.480 1.00 61.87  ?  173 TYR E CG  1 
ATOM   5695 C CD1 . TYR C 3 174 ? 62.961  114.135 105.788 1.00 61.87  ?  173 TYR E CD1 1 
ATOM   5696 C CD2 . TYR C 3 174 ? 61.998  112.008 105.320 1.00 61.87  ?  173 TYR E CD2 1 
ATOM   5697 C CE1 . TYR C 3 174 ? 64.203  113.547 105.930 1.00 61.87  ?  173 TYR E CE1 1 
ATOM   5698 C CE2 . TYR C 3 174 ? 63.236  111.411 105.461 1.00 61.87  ?  173 TYR E CE2 1 
ATOM   5699 C CZ  . TYR C 3 174 ? 64.335  112.185 105.766 1.00 61.87  ?  173 TYR E CZ  1 
ATOM   5700 O OH  . TYR C 3 174 ? 65.570  111.597 105.907 1.00 61.87  ?  173 TYR E OH  1 
ATOM   5701 N N   . LEU C 3 175 ? 57.738  115.160 107.545 1.00 66.43  ?  174 LEU E N   1 
ATOM   5702 C CA  . LEU C 3 175 ? 56.457  115.854 107.564 1.00 66.43  ?  174 LEU E CA  1 
ATOM   5703 C C   . LEU C 3 175 ? 56.562  117.055 108.490 1.00 66.43  ?  174 LEU E C   1 
ATOM   5704 O O   . LEU C 3 175 ? 56.998  116.920 109.637 1.00 66.43  ?  174 LEU E O   1 
ATOM   5705 C CB  . LEU C 3 175 ? 55.329  114.926 108.027 1.00 66.43  ?  174 LEU E CB  1 
ATOM   5706 C CG  . LEU C 3 175 ? 53.926  115.538 108.053 1.00 66.43  ?  174 LEU E CG  1 
ATOM   5707 C CD1 . LEU C 3 175 ? 53.431  115.818 106.641 1.00 66.43  ?  174 LEU E CD1 1 
ATOM   5708 C CD2 . LEU C 3 175 ? 52.964  114.626 108.795 1.00 66.43  ?  174 LEU E CD2 1 
ATOM   5709 N N   . TYR C 3 176 ? 56.158  118.222 107.994 1.00 64.80  ?  175 TYR E N   1 
ATOM   5710 C CA  . TYR C 3 176 ? 56.199  119.461 108.756 1.00 64.80  ?  175 TYR E CA  1 
ATOM   5711 C C   . TYR C 3 176 ? 54.818  120.100 108.773 1.00 64.80  ?  175 TYR E C   1 
ATOM   5712 O O   . TYR C 3 176 ? 54.130  120.143 107.748 1.00 64.80  ?  175 TYR E O   1 
ATOM   5713 C CB  . TYR C 3 176 ? 57.218  120.440 108.163 1.00 64.80  ?  175 TYR E CB  1 
ATOM   5714 C CG  . TYR C 3 176 ? 58.650  119.963 108.257 1.00 64.80  ?  175 TYR E CG  1 
ATOM   5715 C CD1 . TYR C 3 176 ? 59.150  119.024 107.365 1.00 64.80  ?  175 TYR E CD1 1 
ATOM   5716 C CD2 . TYR C 3 176 ? 59.503  120.456 109.235 1.00 64.80  ?  175 TYR E CD2 1 
ATOM   5717 C CE1 . TYR C 3 176 ? 60.457  118.587 107.447 1.00 64.80  ?  175 TYR E CE1 1 
ATOM   5718 C CE2 . TYR C 3 176 ? 60.812  120.025 109.325 1.00 64.80  ?  175 TYR E CE2 1 
ATOM   5719 C CZ  . TYR C 3 176 ? 61.284  119.090 108.428 1.00 64.80  ?  175 TYR E CZ  1 
ATOM   5720 O OH  . TYR C 3 176 ? 62.587  118.657 108.512 1.00 64.80  ?  175 TYR E OH  1 
ATOM   5721 N N   . TRP C 3 177 ? 54.419  120.593 109.942 1.00 68.22  ?  176 TRP E N   1 
ATOM   5722 C CA  . TRP C 3 177 ? 53.149  121.282 110.126 1.00 68.22  ?  176 TRP E CA  1 
ATOM   5723 C C   . TRP C 3 177 ? 53.419  122.721 110.537 1.00 68.22  ?  176 TRP E C   1 
ATOM   5724 O O   . TRP C 3 177 ? 54.193  122.968 111.468 1.00 68.22  ?  176 TRP E O   1 
ATOM   5725 C CB  . TRP C 3 177 ? 52.286  120.583 111.181 1.00 68.22  ?  176 TRP E CB  1 
ATOM   5726 C CG  . TRP C 3 177 ? 51.765  119.249 110.744 1.00 68.22  ?  176 TRP E CG  1 
ATOM   5727 C CD1 . TRP C 3 177 ? 52.329  118.030 110.983 1.00 68.22  ?  176 TRP E CD1 1 
ATOM   5728 C CD2 . TRP C 3 177 ? 50.573  118.998 109.990 1.00 68.22  ?  176 TRP E CD2 1 
ATOM   5729 N NE1 . TRP C 3 177 ? 51.562  117.035 110.426 1.00 68.22  ?  176 TRP E NE1 1 
ATOM   5730 C CE2 . TRP C 3 177 ? 50.478  117.604 109.810 1.00 68.22  ?  176 TRP E CE2 1 
ATOM   5731 C CE3 . TRP C 3 177 ? 49.576  119.817 109.450 1.00 68.22  ?  176 TRP E CE3 1 
ATOM   5732 C CZ2 . TRP C 3 177 ? 49.427  117.010 109.114 1.00 68.22  ?  176 TRP E CZ2 1 
ATOM   5733 C CZ3 . TRP C 3 177 ? 48.534  119.226 108.759 1.00 68.22  ?  176 TRP E CZ3 1 
ATOM   5734 C CH2 . TRP C 3 177 ? 48.468  117.836 108.597 1.00 68.22  ?  176 TRP E CH2 1 
ATOM   5735 N N   . PHE C 3 178 ? 52.782  123.664 109.847 1.00 66.91  ?  177 PHE E N   1 
ATOM   5736 C CA  . PHE C 3 178 ? 52.960  125.087 110.107 1.00 66.91  ?  177 PHE E CA  1 
ATOM   5737 C C   . PHE C 3 178 ? 51.605  125.726 110.376 1.00 66.91  ?  177 PHE E C   1 
ATOM   5738 O O   . PHE C 3 178 ? 50.682  125.593 109.567 1.00 66.91  ?  177 PHE E O   1 
ATOM   5739 C CB  . PHE C 3 178 ? 53.647  125.778 108.926 1.00 66.91  ?  177 PHE E CB  1 
ATOM   5740 C CG  . PHE C 3 178 ? 54.941  125.135 108.518 1.00 66.91  ?  177 PHE E CG  1 
ATOM   5741 C CD1 . PHE C 3 178 ? 56.111  125.403 109.208 1.00 66.91  ?  177 PHE E CD1 1 
ATOM   5742 C CD2 . PHE C 3 178 ? 54.987  124.264 107.442 1.00 66.91  ?  177 PHE E CD2 1 
ATOM   5743 C CE1 . PHE C 3 178 ? 57.303  124.812 108.834 1.00 66.91  ?  177 PHE E CE1 1 
ATOM   5744 C CE2 . PHE C 3 178 ? 56.176  123.671 107.064 1.00 66.91  ?  177 PHE E CE2 1 
ATOM   5745 C CZ  . PHE C 3 178 ? 57.335  123.946 107.760 1.00 66.91  ?  177 PHE E CZ  1 
ATOM   5746 N N   . LEU C 3 179 ? 51.491  126.422 111.504 1.00 70.33  ?  178 LEU E N   1 
ATOM   5747 C CA  . LEU C 3 179 ? 50.249  127.066 111.918 1.00 70.33  ?  178 LEU E CA  1 
ATOM   5748 C C   . LEU C 3 179 ? 50.392  128.572 111.733 1.00 70.33  ?  178 LEU E C   1 
ATOM   5749 O O   . LEU C 3 179 ? 51.185  129.216 112.427 1.00 70.33  ?  178 LEU E O   1 
ATOM   5750 C CB  . LEU C 3 179 ? 49.915  126.722 113.369 1.00 70.33  ?  178 LEU E CB  1 
ATOM   5751 C CG  . LEU C 3 179 ? 48.746  127.491 113.989 1.00 70.33  ?  178 LEU E CG  1 
ATOM   5752 C CD1 . LEU C 3 179 ? 47.506  127.393 113.113 1.00 70.33  ?  178 LEU E CD1 1 
ATOM   5753 C CD2 . LEU C 3 179 ? 48.455  126.977 115.390 1.00 70.33  ?  178 LEU E CD2 1 
ATOM   5754 N N   . GLN C 3 180 ? 49.623  129.127 110.800 1.00 69.76  ?  179 GLN E N   1 
ATOM   5755 C CA  . GLN C 3 180 ? 49.606  130.560 110.537 1.00 69.76  ?  179 GLN E CA  1 
ATOM   5756 C C   . GLN C 3 180 ? 48.350  131.157 111.159 1.00 69.76  ?  179 GLN E C   1 
ATOM   5757 O O   . GLN C 3 180 ? 47.232  130.748 110.825 1.00 69.76  ?  179 GLN E O   1 
ATOM   5758 C CB  . GLN C 3 180 ? 49.648  130.838 109.034 1.00 69.76  ?  179 GLN E CB  1 
ATOM   5759 C CG  . GLN C 3 180 ? 49.704  132.315 108.677 1.00 69.76  ?  179 GLN E CG  1 
ATOM   5760 C CD  . GLN C 3 180 ? 49.777  132.550 107.181 1.00 69.76  ?  179 GLN E CD  1 
ATOM   5761 O OE1 . GLN C 3 180 ? 49.768  131.605 106.391 1.00 69.76  ?  179 GLN E OE1 1 
ATOM   5762 N NE2 . GLN C 3 180 ? 49.850  133.815 106.783 1.00 69.76  ?  179 GLN E NE2 1 
ATOM   5763 N N   . ARG C 3 181 ? 48.538  132.111 112.063 1.00 72.61  ?  180 ARG E N   1 
ATOM   5764 C CA  . ARG C 3 181 ? 47.447  132.779 112.751 1.00 72.61  ?  180 ARG E CA  1 
ATOM   5765 C C   . ARG C 3 181 ? 47.151  134.125 112.107 1.00 72.61  ?  180 ARG E C   1 
ATOM   5766 O O   . ARG C 3 181 ? 47.961  134.649 111.337 1.00 72.61  ?  180 ARG E O   1 
ATOM   5767 C CB  . ARG C 3 181 ? 47.797  132.977 114.230 1.00 72.61  ?  180 ARG E CB  1 
ATOM   5768 C CG  . ARG C 3 181 ? 48.003  131.679 114.994 1.00 72.61  ?  180 ARG E CG  1 
ATOM   5769 C CD  . ARG C 3 181 ? 48.442  131.939 116.426 1.00 72.61  ?  180 ARG E CD  1 
ATOM   5770 N NE  . ARG C 3 181 ? 48.602  130.701 117.184 1.00 72.61  ?  180 ARG E NE  1 
ATOM   5771 C CZ  . ARG C 3 181 ? 49.680  129.924 117.138 1.00 72.61  ?  180 ARG E CZ  1 
ATOM   5772 N NH1 . ARG C 3 181 ? 50.709  130.245 116.364 1.00 72.61  1  180 ARG E NH1 1 
ATOM   5773 N NH2 . ARG C 3 181 ? 49.729  128.817 117.867 1.00 72.61  ?  180 ARG E NH2 1 
ATOM   5774 N N   . PRO C 3 182 ? 45.992  134.715 112.396 1.00 74.37  ?  181 PRO E N   1 
ATOM   5775 C CA  . PRO C 3 182 ? 45.666  136.026 111.811 1.00 74.37  ?  181 PRO E CA  1 
ATOM   5776 C C   . PRO C 3 182 ? 46.701  137.075 112.188 1.00 74.37  ?  181 PRO E C   1 
ATOM   5777 O O   . PRO C 3 182 ? 46.883  137.402 113.363 1.00 74.37  ?  181 PRO E O   1 
ATOM   5778 C CB  . PRO C 3 182 ? 44.288  136.345 112.403 1.00 74.37  ?  181 PRO E CB  1 
ATOM   5779 C CG  . PRO C 3 182 ? 43.716  135.022 112.777 1.00 74.37  ?  181 PRO E CG  1 
ATOM   5780 C CD  . PRO C 3 182 ? 44.879  134.181 113.200 1.00 74.37  ?  181 PRO E CD  1 
ATOM   5781 N N   . GLY C 3 183 ? 47.385  137.604 111.173 1.00 75.00  ?  182 GLY E N   1 
ATOM   5782 C CA  . GLY C 3 183 ? 48.379  138.633 111.361 1.00 75.00  ?  182 GLY E CA  1 
ATOM   5783 C C   . GLY C 3 183 ? 49.776  138.129 111.660 1.00 75.00  ?  182 GLY E C   1 
ATOM   5784 O O   . GLY C 3 183 ? 50.733  138.905 111.556 1.00 75.00  ?  182 GLY E O   1 
ATOM   5785 N N   . GLN C 3 184 ? 49.923  136.860 112.024 1.00 72.63  ?  183 GLN E N   1 
ATOM   5786 C CA  . GLN C 3 184 ? 51.214  136.271 112.344 1.00 72.63  ?  183 GLN E CA  1 
ATOM   5787 C C   . GLN C 3 184 ? 51.659  135.340 111.223 1.00 72.63  ?  183 GLN E C   1 
ATOM   5788 O O   . GLN C 3 184 ? 50.891  134.993 110.322 1.00 72.63  ?  183 GLN E O   1 
ATOM   5789 C CB  . GLN C 3 184 ? 51.148  135.510 113.674 1.00 72.63  ?  183 GLN E CB  1 
ATOM   5790 C CG  . GLN C 3 184 ? 50.803  136.382 114.869 1.00 72.63  ?  183 GLN E CG  1 
ATOM   5791 C CD  . GLN C 3 184 ? 50.770  135.602 116.169 1.00 72.63  ?  183 GLN E CD  1 
ATOM   5792 O OE1 . GLN C 3 184 ? 50.973  134.388 116.183 1.00 72.63  ?  183 GLN E OE1 1 
ATOM   5793 N NE2 . GLN C 3 184 ? 50.514  136.299 117.271 1.00 72.63  ?  183 GLN E NE2 1 
ATOM   5794 N N   . SER C 3 185 ? 52.923  134.936 111.293 1.00 68.84  ?  184 SER E N   1 
ATOM   5795 C CA  . SER C 3 185 ? 53.506  134.037 110.311 1.00 68.84  ?  184 SER E CA  1 
ATOM   5796 C C   . SER C 3 185 ? 53.303  132.588 110.728 1.00 68.84  ?  184 SER E C   1 
ATOM   5797 O O   . SER C 3 185 ? 52.993  132.300 111.888 1.00 68.84  ?  184 SER E O   1 
ATOM   5798 C CB  . SER C 3 185 ? 54.996  134.332 110.152 1.00 68.84  ?  184 SER E CB  1 
ATOM   5799 O OG  . SER C 3 185 ? 55.688  134.135 111.373 1.00 68.84  ?  184 SER E OG  1 
ATOM   5800 N N   . PRO C 3 186 ? 53.463  131.645 109.800 1.00 67.16  ?  185 PRO E N   1 
ATOM   5801 C CA  . PRO C 3 186 ? 53.296  130.230 110.157 1.00 67.16  ?  185 PRO E CA  1 
ATOM   5802 C C   . PRO C 3 186 ? 54.243  129.826 111.279 1.00 67.16  ?  185 PRO E C   1 
ATOM   5803 O O   . PRO C 3 186 ? 55.435  130.136 111.251 1.00 67.16  ?  185 PRO E O   1 
ATOM   5804 C CB  . PRO C 3 186 ? 53.615  129.493 108.851 1.00 67.16  ?  185 PRO E CB  1 
ATOM   5805 C CG  . PRO C 3 186 ? 53.379  130.496 107.776 1.00 67.16  ?  185 PRO E CG  1 
ATOM   5806 C CD  . PRO C 3 186 ? 53.746  131.822 108.365 1.00 67.16  ?  185 PRO E CD  1 
ATOM   5807 N N   . GLN C 3 187 ? 53.697  129.130 112.273 1.00 67.88  ?  186 GLN E N   1 
ATOM   5808 C CA  . GLN C 3 187 ? 54.458  128.657 113.422 1.00 67.88  ?  186 GLN E CA  1 
ATOM   5809 C C   . GLN C 3 187 ? 54.607  127.145 113.337 1.00 67.88  ?  186 GLN E C   1 
ATOM   5810 O O   . GLN C 3 187 ? 53.636  126.436 113.050 1.00 67.88  ?  186 GLN E O   1 
ATOM   5811 C CB  . GLN C 3 187 ? 53.772  129.051 114.733 1.00 67.88  ?  186 GLN E CB  1 
ATOM   5812 C CG  . GLN C 3 187 ? 54.549  128.656 115.979 1.00 67.88  ?  186 GLN E CG  1 
ATOM   5813 C CD  . GLN C 3 187 ? 53.890  129.140 117.256 1.00 67.88  ?  186 GLN E CD  1 
ATOM   5814 O OE1 . GLN C 3 187 ? 52.857  129.809 117.220 1.00 67.88  ?  186 GLN E OE1 1 
ATOM   5815 N NE2 . GLN C 3 187 ? 54.486  128.805 118.394 1.00 67.88  ?  186 GLN E NE2 1 
ATOM   5816 N N   . LEU C 3 188 ? 55.819  126.658 113.588 1.00 65.38  ?  187 LEU E N   1 
ATOM   5817 C CA  . LEU C 3 188 ? 56.088  125.230 113.498 1.00 65.38  ?  187 LEU E CA  1 
ATOM   5818 C C   . LEU C 3 188 ? 55.432  124.491 114.658 1.00 65.38  ?  187 LEU E C   1 
ATOM   5819 O O   . LEU C 3 188 ? 55.626  124.847 115.825 1.00 65.38  ?  187 LEU E O   1 
ATOM   5820 C CB  . LEU C 3 188 ? 57.595  124.976 113.497 1.00 65.38  ?  187 LEU E CB  1 
ATOM   5821 C CG  . LEU C 3 188 ? 58.036  123.516 113.373 1.00 65.38  ?  187 LEU E CG  1 
ATOM   5822 C CD1 . LEU C 3 188 ? 57.641  122.944 112.020 1.00 65.38  ?  187 LEU E CD1 1 
ATOM   5823 C CD2 . LEU C 3 188 ? 59.536  123.388 113.595 1.00 65.38  ?  187 LEU E CD2 1 
ATOM   5824 N N   . LEU C 3 189 ? 54.654  123.460 114.333 1.00 68.44  ?  188 LEU E N   1 
ATOM   5825 C CA  . LEU C 3 189 ? 54.034  122.592 115.328 1.00 68.44  ?  188 LEU E CA  1 
ATOM   5826 C C   . LEU C 3 189 ? 54.755  121.256 115.451 1.00 68.44  ?  188 LEU E C   1 
ATOM   5827 O O   . LEU C 3 189 ? 55.132  120.852 116.555 1.00 68.44  ?  188 LEU E O   1 
ATOM   5828 C CB  . LEU C 3 189 ? 52.561  122.355 114.975 1.00 68.44  ?  188 LEU E CB  1 
ATOM   5829 C CG  . LEU C 3 189 ? 51.670  123.597 114.896 1.00 68.44  ?  188 LEU E CG  1 
ATOM   5830 C CD1 . LEU C 3 189 ? 50.263  123.205 114.476 1.00 68.44  ?  188 LEU E CD1 1 
ATOM   5831 C CD2 . LEU C 3 189 ? 51.645  124.341 116.223 1.00 68.44  ?  188 LEU E CD2 1 
ATOM   5832 N N   . ILE C 3 190 ? 54.953  120.561 114.334 1.00 66.48  ?  189 ILE E N   1 
ATOM   5833 C CA  . ILE C 3 190 ? 55.661  119.287 114.306 1.00 66.48  ?  189 ILE E CA  1 
ATOM   5834 C C   . ILE C 3 190 ? 56.610  119.301 113.116 1.00 66.48  ?  189 ILE E C   1 
ATOM   5835 O O   . ILE C 3 190 ? 56.269  119.813 112.044 1.00 66.48  ?  189 ILE E O   1 
ATOM   5836 C CB  . ILE C 3 190 ? 54.687  118.093 114.219 1.00 66.48  ?  189 ILE E CB  1 
ATOM   5837 C CG1 . ILE C 3 190 ? 53.686  118.139 115.377 1.00 66.48  ?  189 ILE E CG1 1 
ATOM   5838 C CG2 . ILE C 3 190 ? 55.456  116.774 114.228 1.00 66.48  ?  189 ILE E CG2 1 
ATOM   5839 C CD1 . ILE C 3 190 ? 52.644  117.041 115.338 1.00 66.48  ?  189 ILE E CD1 1 
ATOM   5840 N N   . TYR C 3 191 ? 57.805  118.742 113.309 1.00 64.13  ?  190 TYR E N   1 
ATOM   5841 C CA  . TYR C 3 191 ? 58.821  118.688 112.266 1.00 64.13  ?  190 TYR E CA  1 
ATOM   5842 C C   . TYR C 3 191 ? 59.099  117.284 111.756 1.00 64.13  ?  190 TYR E C   1 
ATOM   5843 O O   . TYR C 3 191 ? 59.413  117.123 110.575 1.00 64.13  ?  190 TYR E O   1 
ATOM   5844 C CB  . TYR C 3 191 ? 60.135  119.300 112.769 1.00 64.13  ?  190 TYR E CB  1 
ATOM   5845 C CG  . TYR C 3 191 ? 60.644  118.699 114.060 1.00 64.13  ?  190 TYR E CG  1 
ATOM   5846 C CD1 . TYR C 3 191 ? 60.288  119.239 115.288 1.00 64.13  ?  190 TYR E CD1 1 
ATOM   5847 C CD2 . TYR C 3 191 ? 61.485  117.594 114.051 1.00 64.13  ?  190 TYR E CD2 1 
ATOM   5848 C CE1 . TYR C 3 191 ? 60.752  118.694 116.471 1.00 64.13  ?  190 TYR E CE1 1 
ATOM   5849 C CE2 . TYR C 3 191 ? 61.953  117.042 115.228 1.00 64.13  ?  190 TYR E CE2 1 
ATOM   5850 C CZ  . TYR C 3 191 ? 61.584  117.596 116.434 1.00 64.13  ?  190 TYR E CZ  1 
ATOM   5851 O OH  . TYR C 3 191 ? 62.049  117.051 117.609 1.00 64.13  ?  190 TYR E OH  1 
ATOM   5852 N N   . ARG C 3 192 ? 58.998  116.270 112.610 1.00 62.73  ?  191 ARG E N   1 
ATOM   5853 C CA  . ARG C 3 192 ? 59.208  114.888 112.190 1.00 62.73  ?  191 ARG E CA  1 
ATOM   5854 C C   . ARG C 3 192 ? 58.386  113.935 113.051 1.00 62.73  ?  191 ARG E C   1 
ATOM   5855 O O   . ARG C 3 192 ? 58.501  112.716 112.927 1.00 62.73  ?  191 ARG E O   1 
ATOM   5856 C CB  . ARG C 3 192 ? 60.691  114.517 112.266 1.00 62.73  ?  191 ARG E CB  1 
ATOM   5857 C CG  . ARG C 3 192 ? 61.563  115.215 111.234 1.00 62.73  ?  191 ARG E CG  1 
ATOM   5858 C CD  . ARG C 3 192 ? 62.989  114.687 111.261 1.00 62.73  ?  191 ARG E CD  1 
ATOM   5859 N NE  . ARG C 3 192 ? 63.626  114.885 112.562 1.00 62.73  ?  191 ARG E NE  1 
ATOM   5860 C CZ  . ARG C 3 192 ? 64.246  116.000 112.936 1.00 62.73  ?  191 ARG E CZ  1 
ATOM   5861 N NH1 . ARG C 3 192 ? 64.794  116.078 114.141 1.00 62.73  1  191 ARG E NH1 1 
ATOM   5862 N NH2 . ARG C 3 192 ? 64.319  117.040 112.115 1.00 62.73  ?  191 ARG E NH2 1 
ATOM   5863 N N   . SER C 3 194 ? 55.704  113.351 114.534 1.00 65.97  ?  193 SER E N   1 
ATOM   5864 C CA  . SER C 3 194 ? 55.236  113.086 115.889 1.00 65.97  ?  193 SER E CA  1 
ATOM   5865 C C   . SER C 3 194 ? 56.057  113.868 116.910 1.00 65.97  ?  193 SER E C   1 
ATOM   5866 O O   . SER C 3 194 ? 55.550  114.248 117.966 1.00 65.97  ?  193 SER E O   1 
ATOM   5867 C CB  . SER C 3 194 ? 55.304  111.589 116.195 1.00 65.97  ?  193 SER E CB  1 
ATOM   5868 O OG  . SER C 3 194 ? 56.630  111.103 116.078 1.00 65.97  ?  193 SER E OG  1 
ATOM   5869 N N   . ASN C 3 195 ? 57.326  114.104 116.589 1.00 64.32  ?  194 ASN E N   1 
ATOM   5870 C CA  . ASN C 3 195 ? 58.215  114.845 117.479 1.00 64.32  ?  194 ASN E CA  1 
ATOM   5871 C C   . ASN C 3 195 ? 57.737  116.288 117.583 1.00 64.32  ?  194 ASN E C   1 
ATOM   5872 O O   . ASN C 3 195 ? 57.856  117.061 116.627 1.00 64.32  ?  194 ASN E O   1 
ATOM   5873 C CB  . ASN C 3 195 ? 59.650  114.780 116.965 1.00 64.32  ?  194 ASN E CB  1 
ATOM   5874 C CG  . ASN C 3 195 ? 60.199  113.367 116.950 1.00 64.32  ?  194 ASN E CG  1 
ATOM   5875 O OD1 . ASN C 3 195 ? 60.784  112.905 117.929 1.00 64.32  ?  194 ASN E OD1 1 
ATOM   5876 N ND2 . ASN C 3 195 ? 60.013  112.671 115.834 1.00 64.32  ?  194 ASN E ND2 1 
ATOM   5877 N N   . LEU C 3 196 ? 57.194  116.652 118.742 1.00 67.01  ?  195 LEU E N   1 
ATOM   5878 C CA  . LEU C 3 196 ? 56.691  118.003 118.942 1.00 67.01  ?  195 LEU E CA  1 
ATOM   5879 C C   . LEU C 3 196 ? 57.809  119.023 118.755 1.00 67.01  ?  195 LEU E C   1 
ATOM   5880 O O   . LEU C 3 196 ? 58.985  118.745 119.003 1.00 67.01  ?  195 LEU E O   1 
ATOM   5881 C CB  . LEU C 3 196 ? 56.082  118.139 120.338 1.00 67.01  ?  195 LEU E CB  1 
ATOM   5882 C CG  . LEU C 3 196 ? 55.411  119.476 120.663 1.00 67.01  ?  195 LEU E CG  1 
ATOM   5883 C CD1 . LEU C 3 196 ? 54.225  119.725 119.744 1.00 67.01  ?  195 LEU E CD1 1 
ATOM   5884 C CD2 . LEU C 3 196 ? 54.982  119.512 122.120 1.00 67.01  ?  195 LEU E CD2 1 
ATOM   5885 N N   . ALA C 3 197 ? 57.428  120.218 118.315 1.00 65.43  ?  196 ALA E N   1 
ATOM   5886 C CA  . ALA C 3 197 ? 58.376  121.294 118.083 1.00 65.43  ?  196 ALA E CA  1 
ATOM   5887 C C   . ALA C 3 197 ? 58.585  122.108 119.358 1.00 65.43  ?  196 ALA E C   1 
ATOM   5888 O O   . ALA C 3 197 ? 57.880  121.948 120.357 1.00 65.43  ?  196 ALA E O   1 
ATOM   5889 C CB  . ALA C 3 197 ? 57.893  122.197 116.948 1.00 65.43  ?  196 ALA E CB  1 
ATOM   5890 N N   . SER C 3 198 ? 59.576  122.994 119.313 1.00 65.76  ?  197 SER E N   1 
ATOM   5891 C CA  . SER C 3 198 ? 59.896  123.831 120.458 1.00 65.76  ?  197 SER E CA  1 
ATOM   5892 C C   . SER C 3 198 ? 58.904  124.981 120.579 1.00 65.76  ?  197 SER E C   1 
ATOM   5893 O O   . SER C 3 198 ? 58.370  125.480 119.584 1.00 65.76  ?  197 SER E O   1 
ATOM   5894 C CB  . SER C 3 198 ? 61.317  124.383 120.337 1.00 65.76  ?  197 SER E CB  1 
ATOM   5895 O OG  . SER C 3 198 ? 61.462  125.166 119.164 1.00 65.76  ?  197 SER E OG  1 
ATOM   5896 N N   . GLY C 3 199 ? 58.660  125.400 121.819 1.00 67.47  ?  198 GLY E N   1 
ATOM   5897 C CA  . GLY C 3 199 ? 57.757  126.498 122.093 1.00 67.47  ?  198 GLY E CA  1 
ATOM   5898 C C   . GLY C 3 199 ? 56.294  126.214 121.838 1.00 67.47  ?  198 GLY E C   1 
ATOM   5899 O O   . GLY C 3 199 ? 55.473  127.126 121.991 1.00 67.47  ?  198 GLY E O   1 
ATOM   5900 N N   . VAL C 3 200 ? 55.939  124.995 121.461 1.00 68.53  ?  199 VAL E N   1 
ATOM   5901 C CA  . VAL C 3 200 ? 54.555  124.620 121.178 1.00 68.53  ?  199 VAL E CA  1 
ATOM   5902 C C   . VAL C 3 200 ? 54.057  123.742 122.322 1.00 68.53  ?  199 VAL E C   1 
ATOM   5903 O O   . VAL C 3 200 ? 54.756  122.792 122.701 1.00 68.53  ?  199 VAL E O   1 
ATOM   5904 C CB  . VAL C 3 200 ? 54.434  123.880 119.834 1.00 68.53  ?  199 VAL E CB  1 
ATOM   5905 C CG1 . VAL C 3 200 ? 52.989  123.461 119.589 1.00 68.53  ?  199 VAL E CG1 1 
ATOM   5906 C CG2 . VAL C 3 200 ? 54.952  124.755 118.698 1.00 68.53  ?  199 VAL E CG2 1 
ATOM   5907 N N   . PRO C 3 201 ? 52.884  124.016 122.894 1.00 71.37  ?  200 PRO E N   1 
ATOM   5908 C CA  . PRO C 3 201 ? 52.369  123.145 123.955 1.00 71.37  ?  200 PRO E CA  1 
ATOM   5909 C C   . PRO C 3 201 ? 52.199  121.712 123.472 1.00 71.37  ?  200 PRO E C   1 
ATOM   5910 O O   . PRO C 3 201 ? 52.214  121.421 122.274 1.00 71.37  ?  200 PRO E O   1 
ATOM   5911 C CB  . PRO C 3 201 ? 51.018  123.776 124.315 1.00 71.37  ?  200 PRO E CB  1 
ATOM   5912 C CG  . PRO C 3 201 ? 51.130  125.192 123.880 1.00 71.37  ?  200 PRO E CG  1 
ATOM   5913 C CD  . PRO C 3 201 ? 52.005  125.178 122.665 1.00 71.37  ?  200 PRO E CD  1 
ATOM   5914 N N   . ASP C 3 202 ? 52.033  120.806 124.437 1.00 72.84  ?  201 ASP E N   1 
ATOM   5915 C CA  . ASP C 3 202 ? 51.848  119.391 124.136 1.00 72.84  ?  201 ASP E CA  1 
ATOM   5916 C C   . ASP C 3 202 ? 50.468  119.078 123.573 1.00 72.84  ?  201 ASP E C   1 
ATOM   5917 O O   . ASP C 3 202 ? 50.193  117.908 123.283 1.00 72.84  ?  201 ASP E O   1 
ATOM   5918 C CB  . ASP C 3 202 ? 52.089  118.557 125.396 1.00 72.84  ?  201 ASP E CB  1 
ATOM   5919 C CG  . ASP C 3 202 ? 53.488  118.731 125.952 1.00 72.84  ?  201 ASP E CG  1 
ATOM   5920 O OD1 . ASP C 3 202 ? 54.274  119.499 125.358 1.00 72.84  ?  201 ASP E OD1 1 
ATOM   5921 O OD2 . ASP C 3 202 ? 53.802  118.101 126.984 1.00 72.84  ?  201 ASP E OD2 1 
ATOM   5922 N N   . ARG C 3 203 ? 49.600  120.079 123.411 1.00 75.09  ?  202 ARG E N   1 
ATOM   5923 C CA  . ARG C 3 203 ? 48.261  119.819 122.892 1.00 75.09  ?  202 ARG E CA  1 
ATOM   5924 C C   . ARG C 3 203 ? 48.317  119.263 121.474 1.00 75.09  ?  202 ARG E C   1 
ATOM   5925 O O   . ARG C 3 203 ? 47.514  118.397 121.107 1.00 75.09  ?  202 ARG E O   1 
ATOM   5926 C CB  . ARG C 3 203 ? 47.430  121.101 122.935 1.00 75.09  ?  202 ARG E CB  1 
ATOM   5927 C CG  . ARG C 3 203 ? 47.286  121.692 124.329 1.00 75.09  ?  202 ARG E CG  1 
ATOM   5928 C CD  . ARG C 3 203 ? 46.428  122.949 124.331 1.00 75.09  ?  202 ARG E CD  1 
ATOM   5929 N NE  . ARG C 3 203 ? 47.030  124.039 123.564 1.00 75.09  ?  202 ARG E NE  1 
ATOM   5930 C CZ  . ARG C 3 203 ? 46.805  124.273 122.273 1.00 75.09  ?  202 ARG E CZ  1 
ATOM   5931 N NH1 . ARG C 3 203 ? 45.987  123.496 121.575 1.00 75.09  1  202 ARG E NH1 1 
ATOM   5932 N NH2 . ARG C 3 203 ? 47.406  125.293 121.675 1.00 75.09  ?  202 ARG E NH2 1 
ATOM   5933 N N   . PHE C 3 204 ? 49.255  119.746 120.664 1.00 72.09  ?  203 PHE E N   1 
ATOM   5934 C CA  . PHE C 3 204 ? 49.391  119.280 119.291 1.00 72.09  ?  203 PHE E CA  1 
ATOM   5935 C C   . PHE C 3 204 ? 50.162  117.967 119.258 1.00 72.09  ?  203 PHE E C   1 
ATOM   5936 O O   . PHE C 3 204 ? 51.191  117.824 119.926 1.00 72.09  ?  203 PHE E O   1 
ATOM   5937 C CB  . PHE C 3 204 ? 50.105  120.330 118.440 1.00 72.09  ?  203 PHE E CB  1 
ATOM   5938 C CG  . PHE C 3 204 ? 49.397  121.654 118.387 1.00 72.09  ?  203 PHE E CG  1 
ATOM   5939 C CD1 . PHE C 3 204 ? 49.611  122.609 119.367 1.00 72.09  ?  203 PHE E CD1 1 
ATOM   5940 C CD2 . PHE C 3 204 ? 48.523  121.946 117.354 1.00 72.09  ?  203 PHE E CD2 1 
ATOM   5941 C CE1 . PHE C 3 204 ? 48.962  123.828 119.320 1.00 72.09  ?  203 PHE E CE1 1 
ATOM   5942 C CE2 . PHE C 3 204 ? 47.872  123.164 117.301 1.00 72.09  ?  203 PHE E CE2 1 
ATOM   5943 C CZ  . PHE C 3 204 ? 48.092  124.106 118.285 1.00 72.09  ?  203 PHE E CZ  1 
ATOM   5944 N N   . SER C 3 205 ? 49.663  117.008 118.481 1.00 72.32  ?  204 SER E N   1 
ATOM   5945 C CA  . SER C 3 205 ? 50.336  115.729 118.306 1.00 72.32  ?  204 SER E CA  1 
ATOM   5946 C C   . SER C 3 205 ? 50.167  115.271 116.865 1.00 72.32  ?  204 SER E C   1 
ATOM   5947 O O   . SER C 3 205 ? 49.235  115.679 116.169 1.00 72.32  ?  204 SER E O   1 
ATOM   5948 C CB  . SER C 3 205 ? 49.791  114.666 119.269 1.00 72.32  ?  204 SER E CB  1 
ATOM   5949 O OG  . SER C 3 205 ? 50.453  113.427 119.087 1.00 72.32  ?  204 SER E OG  1 
ATOM   5950 N N   . GLY C 3 206 ? 51.081  114.417 116.424 1.00 71.09  ?  205 GLY E N   1 
ATOM   5951 C CA  . GLY C 3 206 ? 51.044  113.896 115.072 1.00 71.09  ?  205 GLY E CA  1 
ATOM   5952 C C   . GLY C 3 206 ? 51.083  112.384 115.065 1.00 71.09  ?  205 GLY E C   1 
ATOM   5953 O O   . GLY C 3 206 ? 51.722  111.752 115.907 1.00 71.09  ?  205 GLY E O   1 
ATOM   5954 N N   . SER C 3 207 ? 50.384  111.805 114.091 1.00 72.75  ?  206 SER E N   1 
ATOM   5955 C CA  . SER C 3 207 ? 50.324  110.356 113.953 1.00 72.75  ?  206 SER E CA  1 
ATOM   5956 C C   . SER C 3 207 ? 50.079  110.011 112.489 1.00 72.75  ?  206 SER E C   1 
ATOM   5957 O O   . SER C 3 207 ? 49.876  110.889 111.648 1.00 72.75  ?  206 SER E O   1 
ATOM   5958 C CB  . SER C 3 207 ? 49.236  109.764 114.854 1.00 72.75  ?  206 SER E CB  1 
ATOM   5959 O OG  . SER C 3 207 ? 47.960  110.283 114.522 1.00 72.75  ?  206 SER E OG  1 
ATOM   5960 N N   . GLY C 3 208 ? 50.097  108.719 112.192 1.00 72.62  ?  207 GLY E N   1 
ATOM   5961 C CA  . GLY C 3 208 ? 49.829  108.215 110.861 1.00 72.62  ?  207 GLY E CA  1 
ATOM   5962 C C   . GLY C 3 208 ? 51.022  107.478 110.284 1.00 72.62  ?  207 GLY E C   1 
ATOM   5963 O O   . GLY C 3 208 ? 52.069  107.332 110.913 1.00 72.62  ?  207 GLY E O   1 
ATOM   5964 N N   . SER C 3 209 ? 50.836  107.010 109.054 1.00 71.56  ?  208 SER E N   1 
ATOM   5965 C CA  . SER C 3 209 ? 51.856  106.280 108.322 1.00 71.56  ?  208 SER E CA  1 
ATOM   5966 C C   . SER C 3 209 ? 52.532  107.212 107.318 1.00 71.56  ?  208 SER E C   1 
ATOM   5967 O O   . SER C 3 209 ? 52.280  108.420 107.287 1.00 71.56  ?  208 SER E O   1 
ATOM   5968 C CB  . SER C 3 209 ? 51.234  105.060 107.638 1.00 71.56  ?  208 SER E CB  1 
ATOM   5969 O OG  . SER C 3 209 ? 50.237  105.450 106.709 1.00 71.56  ?  208 SER E OG  1 
ATOM   5970 N N   . GLY C 3 210 ? 53.405  106.646 106.481 1.00 70.30  ?  209 GLY E N   1 
ATOM   5971 C CA  . GLY C 3 210 ? 54.116  107.444 105.497 1.00 70.30  ?  209 GLY E CA  1 
ATOM   5972 C C   . GLY C 3 210 ? 53.231  108.021 104.412 1.00 70.30  ?  209 GLY E C   1 
ATOM   5973 O O   . GLY C 3 210 ? 53.658  108.940 103.705 1.00 70.30  ?  209 GLY E O   1 
ATOM   5974 N N   . THR C 3 211 ? 52.010  107.505 104.263 1.00 69.88  ?  210 THR E N   1 
ATOM   5975 C CA  . THR C 3 211 ? 51.077  107.984 103.247 1.00 69.88  ?  210 THR E CA  1 
ATOM   5976 C C   . THR C 3 211 ? 50.061  108.960 103.832 1.00 69.88  ?  210 THR E C   1 
ATOM   5977 O O   . THR C 3 211 ? 49.941  110.095 103.362 1.00 69.88  ?  210 THR E O   1 
ATOM   5978 C CB  . THR C 3 211 ? 50.359  106.796 102.592 1.00 69.88  ?  210 THR E CB  1 
ATOM   5979 O OG1 . THR C 3 211 ? 51.326  105.894 102.039 1.00 69.88  ?  210 THR E OG1 1 
ATOM   5980 C CG2 . THR C 3 211 ? 49.427  107.275 101.486 1.00 69.88  ?  210 THR E CG2 1 
ATOM   5981 N N   . ALA C 3 212 ? 49.326  108.535 104.855 1.00 70.86  ?  211 ALA E N   1 
ATOM   5982 C CA  . ALA C 3 212 ? 48.341  109.373 105.519 1.00 70.86  ?  211 ALA E CA  1 
ATOM   5983 C C   . ALA C 3 212 ? 48.911  109.920 106.822 1.00 70.86  ?  211 ALA E C   1 
ATOM   5984 O O   . ALA C 3 212 ? 49.711  109.264 107.495 1.00 70.86  ?  211 ALA E O   1 
ATOM   5985 C CB  . ALA C 3 212 ? 47.058  108.589 105.802 1.00 70.86  ?  211 ALA E CB  1 
ATOM   5986 N N   . PHE C 3 213 ? 48.490  111.134 107.172 1.00 70.26  ?  212 PHE E N   1 
ATOM   5987 C CA  . PHE C 3 213 ? 48.966  111.801 108.374 1.00 70.26  ?  212 PHE E CA  1 
ATOM   5988 C C   . PHE C 3 213 ? 47.787  112.447 109.086 1.00 70.26  ?  212 PHE E C   1 
ATOM   5989 O O   . PHE C 3 213 ? 46.790  112.815 108.459 1.00 70.26  ?  212 PHE E O   1 
ATOM   5990 C CB  . PHE C 3 213 ? 50.029  112.857 108.045 1.00 70.26  ?  212 PHE E CB  1 
ATOM   5991 C CG  . PHE C 3 213 ? 50.996  112.428 106.978 1.00 70.26  ?  212 PHE E CG  1 
ATOM   5992 C CD1 . PHE C 3 213 ? 52.026  111.549 107.268 1.00 70.26  ?  212 PHE E CD1 1 
ATOM   5993 C CD2 . PHE C 3 213 ? 50.872  112.902 105.683 1.00 70.26  ?  212 PHE E CD2 1 
ATOM   5994 C CE1 . PHE C 3 213 ? 52.915  111.154 106.287 1.00 70.26  ?  212 PHE E CE1 1 
ATOM   5995 C CE2 . PHE C 3 213 ? 51.758  112.510 104.698 1.00 70.26  ?  212 PHE E CE2 1 
ATOM   5996 C CZ  . PHE C 3 213 ? 52.780  111.635 105.000 1.00 70.26  ?  212 PHE E CZ  1 
ATOM   5997 N N   . THR C 3 214 ? 47.915  112.590 110.404 1.00 72.16  ?  213 THR E N   1 
ATOM   5998 C CA  . THR C 3 214 ? 46.847  113.130 111.233 1.00 72.16  ?  213 THR E CA  1 
ATOM   5999 C C   . THR C 3 214 ? 47.443  114.036 112.298 1.00 72.16  ?  213 THR E C   1 
ATOM   6000 O O   . THR C 3 214 ? 48.349  113.628 113.034 1.00 72.16  ?  213 THR E O   1 
ATOM   6001 C CB  . THR C 3 214 ? 46.036  112.009 111.896 1.00 72.16  ?  213 THR E CB  1 
ATOM   6002 O OG1 . THR C 3 214 ? 46.901  111.198 112.701 1.00 72.16  ?  213 THR E OG1 1 
ATOM   6003 C CG2 . THR C 3 214 ? 45.362  111.139 110.844 1.00 72.16  ?  213 THR E CG2 1 
ATOM   6004 N N   . LEU C 3 215 ? 46.930  115.262 112.370 1.00 72.30  ?  214 LEU E N   1 
ATOM   6005 C CA  . LEU C 3 215 ? 47.305  116.235 113.388 1.00 72.30  ?  214 LEU E CA  1 
ATOM   6006 C C   . LEU C 3 215 ? 46.156  116.347 114.380 1.00 72.30  ?  214 LEU E C   1 
ATOM   6007 O O   . LEU C 3 215 ? 45.043  116.730 114.004 1.00 72.30  ?  214 LEU E O   1 
ATOM   6008 C CB  . LEU C 3 215 ? 47.613  117.594 112.757 1.00 72.30  ?  214 LEU E CB  1 
ATOM   6009 C CG  . LEU C 3 215 ? 48.108  118.693 113.701 1.00 72.30  ?  214 LEU E CG  1 
ATOM   6010 C CD1 . LEU C 3 215 ? 49.510  118.384 114.203 1.00 72.30  ?  214 LEU E CD1 1 
ATOM   6011 C CD2 . LEU C 3 215 ? 48.071  120.047 113.011 1.00 72.30  ?  214 LEU E CD2 1 
ATOM   6012 N N   . THR C 3 216 ? 46.426  116.014 115.639 1.00 73.82  ?  215 THR E N   1 
ATOM   6013 C CA  . THR C 3 216 ? 45.408  115.950 116.678 1.00 73.82  ?  215 THR E CA  1 
ATOM   6014 C C   . THR C 3 216 ? 45.651  117.038 117.715 1.00 73.82  ?  215 THR E C   1 
ATOM   6015 O O   . THR C 3 216 ? 46.758  117.154 118.255 1.00 73.82  ?  215 THR E O   1 
ATOM   6016 C CB  . THR C 3 216 ? 45.402  114.577 117.354 1.00 73.82  ?  215 THR E CB  1 
ATOM   6017 O OG1 . THR C 3 216 ? 46.685  114.322 117.940 1.00 73.82  ?  215 THR E OG1 1 
ATOM   6018 C CG2 . THR C 3 216 ? 45.082  113.484 116.343 1.00 73.82  ?  215 THR E CG2 1 
ATOM   6019 N N   . ILE C 3 217 ? 44.617  117.830 117.981 1.00 75.17  ?  216 ILE E N   1 
ATOM   6020 C CA  . ILE C 3 217 ? 44.612  118.820 119.052 1.00 75.17  ?  216 ILE E CA  1 
ATOM   6021 C C   . ILE C 3 217 ? 43.636  118.333 120.113 1.00 75.17  ?  216 ILE E C   1 
ATOM   6022 O O   . ILE C 3 217 ? 42.433  118.207 119.849 1.00 75.17  ?  216 ILE E O   1 
ATOM   6023 C CB  . ILE C 3 217 ? 44.223  120.216 118.541 1.00 75.17  ?  216 ILE E CB  1 
ATOM   6024 C CG1 . ILE C 3 217 ? 45.353  120.822 117.703 1.00 75.17  ?  216 ILE E CG1 1 
ATOM   6025 C CG2 . ILE C 3 217 ? 43.882  121.136 119.707 1.00 75.17  ?  216 ILE E CG2 1 
ATOM   6026 C CD1 . ILE C 3 217 ? 45.555  120.159 116.357 1.00 75.17  ?  216 ILE E CD1 1 
ATOM   6027 N N   . SER C 3 218 ? 44.153  118.056 121.311 1.00 76.50  ?  217 SER E N   1 
ATOM   6028 C CA  . SER C 3 218 ? 43.323  117.489 122.368 1.00 76.50  ?  217 SER E CA  1 
ATOM   6029 C C   . SER C 3 218 ? 42.363  118.520 122.949 1.00 76.50  ?  217 SER E C   1 
ATOM   6030 O O   . SER C 3 218 ? 41.189  118.214 123.184 1.00 76.50  ?  217 SER E O   1 
ATOM   6031 C CB  . SER C 3 218 ? 44.208  116.909 123.472 1.00 76.50  ?  217 SER E CB  1 
ATOM   6032 O OG  . SER C 3 218 ? 45.048  115.885 122.968 1.00 76.50  ?  217 SER E OG  1 
ATOM   6033 N N   . ARG C 3 219 ? 42.840  119.741 123.188 1.00 78.23  ?  218 ARG E N   1 
ATOM   6034 C CA  . ARG C 3 219 ? 42.021  120.796 123.776 1.00 78.23  ?  218 ARG E CA  1 
ATOM   6035 C C   . ARG C 3 219 ? 42.243  122.076 122.989 1.00 78.23  ?  218 ARG E C   1 
ATOM   6036 O O   . ARG C 3 219 ? 43.376  122.556 122.888 1.00 78.23  ?  218 ARG E O   1 
ATOM   6037 C CB  . ARG C 3 219 ? 42.366  121.001 125.255 1.00 78.23  ?  218 ARG E CB  1 
ATOM   6038 C CG  . ARG C 3 219 ? 41.420  121.935 125.991 1.00 78.23  ?  218 ARG E CG  1 
ATOM   6039 C CD  . ARG C 3 219 ? 41.662  121.897 127.491 1.00 78.23  ?  218 ARG E CD  1 
ATOM   6040 N NE  . ARG C 3 219 ? 42.998  122.372 127.847 1.00 78.23  ?  218 ARG E NE  1 
ATOM   6041 C CZ  . ARG C 3 219 ? 43.306  123.641 128.098 1.00 78.23  ?  218 ARG E CZ  1 
ATOM   6042 N NH1 . ARG C 3 219 ? 42.378  124.587 128.034 1.00 78.23  1  218 ARG E NH1 1 
ATOM   6043 N NH2 . ARG C 3 219 ? 44.552  123.968 128.413 1.00 78.23  ?  218 ARG E NH2 1 
ATOM   6044 N N   . LEU C 3 220 ? 41.166  122.624 122.433 1.00 78.95  ?  219 LEU E N   1 
ATOM   6045 C CA  . LEU C 3 220 ? 41.259  123.822 121.615 1.00 78.95  ?  219 LEU E CA  1 
ATOM   6046 C C   . LEU C 3 220 ? 41.322  125.069 122.490 1.00 78.95  ?  219 LEU E C   1 
ATOM   6047 O O   . LEU C 3 220 ? 40.789  125.104 123.602 1.00 78.95  ?  219 LEU E O   1 
ATOM   6048 C CB  . LEU C 3 220 ? 40.063  123.912 120.666 1.00 78.95  ?  219 LEU E CB  1 
ATOM   6049 C CG  . LEU C 3 220 ? 40.119  125.007 119.597 1.00 78.95  ?  219 LEU E CG  1 
ATOM   6050 C CD1 . LEU C 3 220 ? 41.197  124.704 118.567 1.00 78.95  ?  219 LEU E CD1 1 
ATOM   6051 C CD2 . LEU C 3 220 ? 38.764  125.166 118.928 1.00 78.95  ?  219 LEU E CD2 1 
ATOM   6052 N N   . GLU C 3 221 ? 41.986  126.100 121.970 1.00 79.14  ?  220 GLU E N   1 
ATOM   6053 C CA  . GLU C 3 221 ? 42.112  127.377 122.656 1.00 79.14  ?  220 GLU E CA  1 
ATOM   6054 C C   . GLU C 3 221 ? 41.851  128.499 121.662 1.00 79.14  ?  220 GLU E C   1 
ATOM   6055 O O   . GLU C 3 221 ? 41.786  128.284 120.448 1.00 79.14  ?  220 GLU E O   1 
ATOM   6056 C CB  . GLU C 3 221 ? 43.496  127.539 123.297 1.00 79.14  ?  220 GLU E CB  1 
ATOM   6057 C CG  . GLU C 3 221 ? 43.750  126.611 124.474 1.00 79.14  ?  220 GLU E CG  1 
ATOM   6058 C CD  . GLU C 3 221 ? 42.896  126.951 125.680 1.00 79.14  ?  220 GLU E CD  1 
ATOM   6059 O OE1 . GLU C 3 221 ? 42.158  127.957 125.626 1.00 79.14  ?  220 GLU E OE1 1 
ATOM   6060 O OE2 . GLU C 3 221 ? 42.963  126.212 126.685 1.00 79.14  ?  220 GLU E OE2 1 
ATOM   6061 N N   . ALA C 3 222 ? 41.700  129.715 122.193 1.00 79.58  ?  221 ALA E N   1 
ATOM   6062 C CA  . ALA C 3 222 ? 41.458  130.873 121.343 1.00 79.58  ?  221 ALA E CA  1 
ATOM   6063 C C   . ALA C 3 222 ? 42.659  131.209 120.468 1.00 79.58  ?  221 ALA E C   1 
ATOM   6064 O O   . ALA C 3 222 ? 42.494  131.878 119.443 1.00 79.58  ?  221 ALA E O   1 
ATOM   6065 C CB  . ALA C 3 222 ? 41.087  132.085 122.199 1.00 79.58  ?  221 ALA E CB  1 
ATOM   6066 N N   . GLU C 3 223 ? 43.855  130.765 120.847 1.00 78.48  ?  222 GLU E N   1 
ATOM   6067 C CA  . GLU C 3 223 ? 45.063  131.018 120.074 1.00 78.48  ?  222 GLU E CA  1 
ATOM   6068 C C   . GLU C 3 223 ? 45.328  129.949 119.022 1.00 78.48  ?  222 GLU E C   1 
ATOM   6069 O O   . GLU C 3 223 ? 46.276  130.089 118.243 1.00 78.48  ?  222 GLU E O   1 
ATOM   6070 C CB  . GLU C 3 223 ? 46.272  131.121 121.011 1.00 78.48  ?  222 GLU E CB  1 
ATOM   6071 C CG  . GLU C 3 223 ? 46.158  132.217 122.059 1.00 78.48  ?  222 GLU E CG  1 
ATOM   6072 C CD  . GLU C 3 223 ? 46.126  133.607 121.453 1.00 78.48  ?  222 GLU E CD  1 
ATOM   6073 O OE1 . GLU C 3 223 ? 46.399  133.737 120.241 1.00 78.48  ?  222 GLU E OE1 1 
ATOM   6074 O OE2 . GLU C 3 223 ? 45.828  134.571 122.189 1.00 78.48  ?  222 GLU E OE2 1 
ATOM   6075 N N   . ASP C 3 224 ? 44.518  128.891 118.978 1.00 77.82  ?  223 ASP E N   1 
ATOM   6076 C CA  . ASP C 3 224 ? 44.710  127.820 118.010 1.00 77.82  ?  223 ASP E CA  1 
ATOM   6077 C C   . ASP C 3 224 ? 44.039  128.098 116.673 1.00 77.82  ?  223 ASP E C   1 
ATOM   6078 O O   . ASP C 3 224 ? 44.371  127.438 115.681 1.00 77.82  ?  223 ASP E O   1 
ATOM   6079 C CB  . ASP C 3 224 ? 44.176  126.500 118.574 1.00 77.82  ?  223 ASP E CB  1 
ATOM   6080 C CG  . ASP C 3 224 ? 44.884  126.080 119.847 1.00 77.82  ?  223 ASP E CG  1 
ATOM   6081 O OD1 . ASP C 3 224 ? 45.792  126.813 120.292 1.00 77.82  ?  223 ASP E OD1 1 
ATOM   6082 O OD2 . ASP C 3 224 ? 44.532  125.018 120.402 1.00 77.82  ?  223 ASP E OD2 1 
ATOM   6083 N N   . VAL C 3 225 ? 43.105  129.050 116.620 1.00 78.09  ?  224 VAL E N   1 
ATOM   6084 C CA  . VAL C 3 225 ? 42.443  129.374 115.363 1.00 78.09  ?  224 VAL E CA  1 
ATOM   6085 C C   . VAL C 3 225 ? 43.484  129.823 114.349 1.00 78.09  ?  224 VAL E C   1 
ATOM   6086 O O   . VAL C 3 225 ? 44.362  130.641 114.652 1.00 78.09  ?  224 VAL E O   1 
ATOM   6087 C CB  . VAL C 3 225 ? 41.369  130.450 115.582 1.00 78.09  ?  224 VAL E CB  1 
ATOM   6088 C CG1 . VAL C 3 225 ? 40.314  129.956 116.561 1.00 78.09  ?  224 VAL E CG1 1 
ATOM   6089 C CG2 . VAL C 3 225 ? 41.998  131.749 116.074 1.00 78.09  ?  224 VAL E CG2 1 
ATOM   6090 N N   . GLY C 3 226 ? 43.391  129.289 113.140 1.00 75.79  ?  225 GLY E N   1 
ATOM   6091 C CA  . GLY C 3 226 ? 44.344  129.617 112.102 1.00 75.79  ?  225 GLY E CA  1 
ATOM   6092 C C   . GLY C 3 226 ? 44.343  128.552 111.022 1.00 75.79  ?  225 GLY E C   1 
ATOM   6093 O O   . GLY C 3 226 ? 43.495  127.661 111.000 1.00 75.79  ?  225 GLY E O   1 
ATOM   6094 N N   . VAL C 3 227 ? 45.321  128.669 110.128 1.00 73.47  ?  226 VAL E N   1 
ATOM   6095 C CA  . VAL C 3 227 ? 45.461  127.772 108.987 1.00 73.47  ?  226 VAL E CA  1 
ATOM   6096 C C   . VAL C 3 227 ? 46.651  126.856 109.234 1.00 73.47  ?  226 VAL E C   1 
ATOM   6097 O O   . VAL C 3 227 ? 47.761  127.326 109.512 1.00 73.47  ?  226 VAL E O   1 
ATOM   6098 C CB  . VAL C 3 227 ? 45.632  128.552 107.672 1.00 73.47  ?  226 VAL E CB  1 
ATOM   6099 C CG1 . VAL C 3 227 ? 45.477  127.618 106.481 1.00 73.47  ?  226 VAL E CG1 1 
ATOM   6100 C CG2 . VAL C 3 227 ? 44.629  129.695 107.596 1.00 73.47  ?  226 VAL E CG2 1 
ATOM   6101 N N   . TYR C 3 228 ? 46.419  125.551 109.129 1.00 72.72  ?  227 TYR E N   1 
ATOM   6102 C CA  . TYR C 3 228 ? 47.456  124.541 109.284 1.00 72.72  ?  227 TYR E CA  1 
ATOM   6103 C C   . TYR C 3 228 ? 47.864  124.047 107.902 1.00 72.72  ?  227 TYR E C   1 
ATOM   6104 O O   . TYR C 3 228 ? 47.024  123.544 107.146 1.00 72.72  ?  227 TYR E O   1 
ATOM   6105 C CB  . TYR C 3 228 ? 46.962  123.378 110.144 1.00 72.72  ?  227 TYR E CB  1 
ATOM   6106 C CG  . TYR C 3 228 ? 46.537  123.779 111.539 1.00 72.72  ?  227 TYR E CG  1 
ATOM   6107 C CD1 . TYR C 3 228 ? 45.311  124.392 111.763 1.00 72.72  ?  227 TYR E CD1 1 
ATOM   6108 C CD2 . TYR C 3 228 ? 47.357  123.536 112.633 1.00 72.72  ?  227 TYR E CD2 1 
ATOM   6109 C CE1 . TYR C 3 228 ? 44.918  124.758 113.036 1.00 72.72  ?  227 TYR E CE1 1 
ATOM   6110 C CE2 . TYR C 3 228 ? 46.971  123.897 113.909 1.00 72.72  ?  227 TYR E CE2 1 
ATOM   6111 C CZ  . TYR C 3 228 ? 45.751  124.508 114.105 1.00 72.72  ?  227 TYR E CZ  1 
ATOM   6112 O OH  . TYR C 3 228 ? 45.362  124.870 115.374 1.00 72.72  ?  227 TYR E OH  1 
ATOM   6113 N N   . TYR C 3 229 ? 49.145  124.198 107.577 1.00 69.07  ?  228 TYR E N   1 
ATOM   6114 C CA  . TYR C 3 229 ? 49.707  123.762 106.308 1.00 69.07  ?  228 TYR E CA  1 
ATOM   6115 C C   . TYR C 3 229 ? 50.644  122.585 106.540 1.00 69.07  ?  228 TYR E C   1 
ATOM   6116 O O   . TYR C 3 229 ? 51.397  122.561 107.520 1.00 69.07  ?  228 TYR E O   1 
ATOM   6117 C CB  . TYR C 3 229 ? 50.473  124.897 105.622 1.00 69.07  ?  228 TYR E CB  1 
ATOM   6118 C CG  . TYR C 3 229 ? 49.694  126.184 105.486 1.00 69.07  ?  228 TYR E CG  1 
ATOM   6119 C CD1 . TYR C 3 229 ? 48.798  126.370 104.442 1.00 69.07  ?  228 TYR E CD1 1 
ATOM   6120 C CD2 . TYR C 3 229 ? 49.863  127.219 106.395 1.00 69.07  ?  228 TYR E CD2 1 
ATOM   6121 C CE1 . TYR C 3 229 ? 48.087  127.547 104.313 1.00 69.07  ?  228 TYR E CE1 1 
ATOM   6122 C CE2 . TYR C 3 229 ? 49.158  128.400 106.274 1.00 69.07  ?  228 TYR E CE2 1 
ATOM   6123 C CZ  . TYR C 3 229 ? 48.272  128.560 105.230 1.00 69.07  ?  228 TYR E CZ  1 
ATOM   6124 O OH  . TYR C 3 229 ? 47.566  129.734 105.104 1.00 69.07  ?  228 TYR E OH  1 
ATOM   6125 N N   . CYS C 3 230 ? 50.593  121.617 105.630 1.00 68.60  ?  229 CYS E N   1 
ATOM   6126 C CA  . CYS C 3 230 ? 51.459  120.450 105.659 1.00 68.60  ?  229 CYS E CA  1 
ATOM   6127 C C   . CYS C 3 230 ? 52.530  120.575 104.582 1.00 68.60  ?  229 CYS E C   1 
ATOM   6128 O O   . CYS C 3 230 ? 52.292  121.137 103.509 1.00 68.60  ?  229 CYS E O   1 
ATOM   6129 C CB  . CYS C 3 230 ? 50.655  119.166 105.443 1.00 68.60  ?  229 CYS E CB  1 
ATOM   6130 S SG  . CYS C 3 230 ? 49.653  119.175 103.939 1.00 68.60  ?  229 CYS E SG  1 
ATOM   6131 N N   . MET C 3 231 ? 53.715  120.047 104.880 1.00 66.57  ?  230 MET E N   1 
ATOM   6132 C CA  . MET C 3 231 ? 54.839  120.107 103.958 1.00 66.57  ?  230 MET E CA  1 
ATOM   6133 C C   . MET C 3 231 ? 55.633  118.813 104.036 1.00 66.57  ?  230 MET E C   1 
ATOM   6134 O O   . MET C 3 231 ? 55.806  118.244 105.118 1.00 66.57  ?  230 MET E O   1 
ATOM   6135 C CB  . MET C 3 231 ? 55.755  121.297 104.273 1.00 66.57  ?  230 MET E CB  1 
ATOM   6136 C CG  . MET C 3 231 ? 56.880  121.499 103.267 1.00 66.57  ?  230 MET E CG  1 
ATOM   6137 S SD  . MET C 3 231 ? 58.012  122.822 103.733 1.00 66.57  ?  230 MET E SD  1 
ATOM   6138 C CE  . MET C 3 231 ? 58.812  122.104 105.166 1.00 66.57  ?  230 MET E CE  1 
ATOM   6139 N N   . GLN C 3 232 ? 56.110  118.355 102.883 1.00 66.35  ?  231 GLN E N   1 
ATOM   6140 C CA  . GLN C 3 232 ? 56.975  117.189 102.787 1.00 66.35  ?  231 GLN E CA  1 
ATOM   6141 C C   . GLN C 3 232 ? 58.403  117.645 102.524 1.00 66.35  ?  231 GLN E C   1 
ATOM   6142 O O   . GLN C 3 232 ? 58.627  118.638 101.824 1.00 66.35  ?  231 GLN E O   1 
ATOM   6143 C CB  . GLN C 3 232 ? 56.505  116.241 101.677 1.00 66.35  ?  231 GLN E CB  1 
ATOM   6144 C CG  . GLN C 3 232 ? 56.489  116.848 100.275 1.00 66.35  ?  231 GLN E CG  1 
ATOM   6145 C CD  . GLN C 3 232 ? 57.851  116.833 99.603  1.00 66.35  ?  231 GLN E CD  1 
ATOM   6146 O OE1 . GLN C 3 232 ? 58.772  116.152 100.053 1.00 66.35  ?  231 GLN E OE1 1 
ATOM   6147 N NE2 . GLN C 3 232 ? 57.983  117.589 98.519  1.00 66.35  ?  231 GLN E NE2 1 
ATOM   6148 N N   . HIS C 3 233 ? 59.370  116.917 103.091 1.00 63.65  ?  232 HIS E N   1 
ATOM   6149 C CA  . HIS C 3 233 ? 60.779  117.269 102.957 1.00 63.65  ?  232 HIS E CA  1 
ATOM   6150 C C   . HIS C 3 233 ? 61.618  116.085 102.489 1.00 63.65  ?  232 HIS E C   1 
ATOM   6151 O O   . HIS C 3 233 ? 62.842  116.093 102.661 1.00 63.65  ?  232 HIS E O   1 
ATOM   6152 C CB  . HIS C 3 233 ? 61.323  117.812 104.282 1.00 63.65  ?  232 HIS E CB  1 
ATOM   6153 C CG  . HIS C 3 233 ? 62.607  118.569 104.143 1.00 63.65  ?  232 HIS E CG  1 
ATOM   6154 N ND1 . HIS C 3 233 ? 63.838  117.950 104.118 1.00 63.65  ?  232 HIS E ND1 1 
ATOM   6155 C CD2 . HIS C 3 233 ? 62.851  119.896 104.024 1.00 63.65  ?  232 HIS E CD2 1 
ATOM   6156 C CE1 . HIS C 3 233 ? 64.785  118.862 103.989 1.00 63.65  ?  232 HIS E CE1 1 
ATOM   6157 N NE2 . HIS C 3 233 ? 64.212  120.051 103.929 1.00 63.65  ?  232 HIS E NE2 1 
ATOM   6158 N N   . LEU C 3 234 ? 60.990  115.066 101.899 1.00 64.08  ?  233 LEU E N   1 
ATOM   6159 C CA  . LEU C 3 234 ? 61.750  113.935 101.378 1.00 64.08  ?  233 LEU E CA  1 
ATOM   6160 C C   . LEU C 3 234 ? 62.688  114.381 100.263 1.00 64.08  ?  233 LEU E C   1 
ATOM   6161 O O   . LEU C 3 234 ? 63.869  114.015 100.244 1.00 64.08  ?  233 LEU E O   1 
ATOM   6162 C CB  . LEU C 3 234 ? 60.794  112.849 100.880 1.00 64.08  ?  233 LEU E CB  1 
ATOM   6163 C CG  . LEU C 3 234 ? 61.442  111.584 100.311 1.00 64.08  ?  233 LEU E CG  1 
ATOM   6164 C CD1 . LEU C 3 234 ? 62.318  110.904 101.352 1.00 64.08  ?  233 LEU E CD1 1 
ATOM   6165 C CD2 . LEU C 3 234 ? 60.377  110.626 99.798  1.00 64.08  ?  233 LEU E CD2 1 
ATOM   6166 N N   . GLU C 3 235 ? 62.177  115.173 99.326  1.00 65.38  ?  234 GLU E N   1 
ATOM   6167 C CA  . GLU C 3 235 ? 62.962  115.724 98.233  1.00 65.38  ?  234 GLU E CA  1 
ATOM   6168 C C   . GLU C 3 235 ? 63.103  117.231 98.408  1.00 65.38  ?  234 GLU E C   1 
ATOM   6169 O O   . GLU C 3 235 ? 62.233  117.890 98.983  1.00 65.38  ?  234 GLU E O   1 
ATOM   6170 C CB  . GLU C 3 235 ? 62.316  115.417 96.879  1.00 65.38  ?  234 GLU E CB  1 
ATOM   6171 C CG  . GLU C 3 235 ? 62.155  113.933 96.592  1.00 65.38  ?  234 GLU E CG  1 
ATOM   6172 C CD  . GLU C 3 235 ? 61.503  113.667 95.250  1.00 65.38  ?  234 GLU E CD  1 
ATOM   6173 O OE1 . GLU C 3 235 ? 61.172  114.643 94.545  1.00 65.38  ?  234 GLU E OE1 1 
ATOM   6174 O OE2 . GLU C 3 235 ? 61.322  112.482 94.900  1.00 65.38  ?  234 GLU E OE2 1 
ATOM   6175 N N   . TYR C 3 236 ? 64.215  117.770 97.908  1.00 65.84  ?  235 TYR E N   1 
ATOM   6176 C CA  . TYR C 3 236 ? 64.461  119.208 98.000  1.00 65.84  ?  235 TYR E CA  1 
ATOM   6177 C C   . TYR C 3 236 ? 63.313  120.047 97.456  1.00 65.84  ?  235 TYR E C   1 
ATOM   6178 O O   . TYR C 3 236 ? 62.856  120.956 98.167  1.00 65.84  ?  235 TYR E O   1 
ATOM   6179 C CB  . TYR C 3 236 ? 65.773  119.545 97.277  1.00 65.84  ?  235 TYR E CB  1 
ATOM   6180 C CG  . TYR C 3 236 ? 66.974  119.652 98.194  1.00 65.84  ?  235 TYR E CG  1 
ATOM   6181 C CD1 . TYR C 3 236 ? 66.948  120.473 99.315  1.00 65.84  ?  235 TYR E CD1 1 
ATOM   6182 C CD2 . TYR C 3 236 ? 68.133  118.930 97.941  1.00 65.84  ?  235 TYR E CD2 1 
ATOM   6183 C CE1 . TYR C 3 236 ? 68.039  120.574 100.155 1.00 65.84  ?  235 TYR E CE1 1 
ATOM   6184 C CE2 . TYR C 3 236 ? 69.231  119.025 98.776  1.00 65.84  ?  235 TYR E CE2 1 
ATOM   6185 C CZ  . TYR C 3 236 ? 69.178  119.848 99.881  1.00 65.84  ?  235 TYR E CZ  1 
ATOM   6186 O OH  . TYR C 3 236 ? 70.267  119.946 100.716 1.00 65.84  ?  235 TYR E OH  1 
ATOM   6187 N N   . PRO C 3 237 ? 62.806  119.819 96.239  1.00 65.17  ?  236 PRO E N   1 
ATOM   6188 C CA  . PRO C 3 237 ? 61.655  120.605 95.775  1.00 65.17  ?  236 PRO E CA  1 
ATOM   6189 C C   . PRO C 3 237 ? 60.421  120.353 96.626  1.00 65.17  ?  236 PRO E C   1 
ATOM   6190 O O   . PRO C 3 237 ? 59.869  119.247 96.625  1.00 65.17  ?  236 PRO E O   1 
ATOM   6191 C CB  . PRO C 3 237 ? 61.459  120.133 94.328  1.00 65.17  ?  236 PRO E CB  1 
ATOM   6192 C CG  . PRO C 3 237 ? 62.122  118.802 94.261  1.00 65.17  ?  236 PRO E CG  1 
ATOM   6193 C CD  . PRO C 3 237 ? 63.274  118.870 95.214  1.00 65.17  ?  236 PRO E CD  1 
ATOM   6194 N N   . LEU C 3 238 ? 59.983  121.373 97.355  1.00 66.12  ?  237 LEU E N   1 
ATOM   6195 C CA  . LEU C 3 238 ? 58.894  121.248 98.311  1.00 66.12  ?  237 LEU E CA  1 
ATOM   6196 C C   . LEU C 3 238 ? 57.570  121.658 97.674  1.00 66.12  ?  237 LEU E C   1 
ATOM   6197 O O   . LEU C 3 238 ? 57.521  122.257 96.597  1.00 66.12  ?  237 LEU E O   1 
ATOM   6198 C CB  . LEU C 3 238 ? 59.177  122.102 99.551  1.00 66.12  ?  237 LEU E CB  1 
ATOM   6199 C CG  . LEU C 3 238 ? 60.599  122.003 100.111 1.00 66.12  ?  237 LEU E CG  1 
ATOM   6200 C CD1 . LEU C 3 238 ? 60.761  122.895 101.330 1.00 66.12  ?  237 LEU E CD1 1 
ATOM   6201 C CD2 . LEU C 3 238 ? 60.953  120.562 100.450 1.00 66.12  ?  237 LEU E CD2 1 
ATOM   6202 N N   . THR C 3 239 ? 56.482  121.322 98.364  1.00 66.94  ?  238 THR E N   1 
ATOM   6203 C CA  . THR C 3 239 ? 55.140  121.660 97.896  1.00 66.94  ?  238 THR E CA  1 
ATOM   6204 C C   . THR C 3 239 ? 54.197  121.616 99.086  1.00 66.94  ?  238 THR E C   1 
ATOM   6205 O O   . THR C 3 239 ? 54.003  120.551 99.681  1.00 66.94  ?  238 THR E O   1 
ATOM   6206 C CB  . THR C 3 239 ? 54.676  120.694 96.803  1.00 66.94  ?  238 THR E CB  1 
ATOM   6207 O OG1 . THR C 3 239 ? 55.602  120.721 95.709  1.00 66.94  ?  238 THR E OG1 1 
ATOM   6208 C CG2 . THR C 3 239 ? 53.290  121.076 96.300  1.00 66.94  ?  238 THR E CG2 1 
ATOM   6209 N N   . PHE C 3 240 ? 53.614  122.760 99.431  1.00 67.09  ?  239 PHE E N   1 
ATOM   6210 C CA  . PHE C 3 240 ? 52.693  122.832 100.553 1.00 67.09  ?  239 PHE E CA  1 
ATOM   6211 C C   . PHE C 3 240 ? 51.292  122.404 100.126 1.00 67.09  ?  239 PHE E C   1 
ATOM   6212 O O   . PHE C 3 240 ? 50.930  122.444 98.947  1.00 67.09  ?  239 PHE E O   1 
ATOM   6213 C CB  . PHE C 3 240 ? 52.650  124.250 101.124 1.00 67.09  ?  239 PHE E CB  1 
ATOM   6214 C CG  . PHE C 3 240 ? 53.959  124.713 101.697 1.00 67.09  ?  239 PHE E CG  1 
ATOM   6215 C CD1 . PHE C 3 240 ? 54.934  125.259 100.880 1.00 67.09  ?  239 PHE E CD1 1 
ATOM   6216 C CD2 . PHE C 3 240 ? 54.211  124.610 103.055 1.00 67.09  ?  239 PHE E CD2 1 
ATOM   6217 C CE1 . PHE C 3 240 ? 56.138  125.688 101.405 1.00 67.09  ?  239 PHE E CE1 1 
ATOM   6218 C CE2 . PHE C 3 240 ? 55.412  125.038 103.586 1.00 67.09  ?  239 PHE E CE2 1 
ATOM   6219 C CZ  . PHE C 3 240 ? 56.377  125.578 102.760 1.00 67.09  ?  239 PHE E CZ  1 
ATOM   6220 N N   . GLY C 3 241 ? 50.499  121.988 101.112 1.00 69.18  ?  240 GLY E N   1 
ATOM   6221 C CA  . GLY C 3 241 ? 49.137  121.569 100.867 1.00 69.18  ?  240 GLY E CA  1 
ATOM   6222 C C   . GLY C 3 241 ? 48.177  122.739 100.774 1.00 69.18  ?  240 GLY E C   1 
ATOM   6223 O O   . GLY C 3 241 ? 48.557  123.910 100.800 1.00 69.18  ?  240 GLY E O   1 
ATOM   6224 N N   . ALA C 3 242 ? 46.891  122.401 100.662 1.00 71.79  ?  241 ALA E N   1 
ATOM   6225 C CA  . ALA C 3 242 ? 45.864  123.434 100.569 1.00 71.79  ?  241 ALA E CA  1 
ATOM   6226 C C   . ALA C 3 242 ? 45.721  124.190 101.883 1.00 71.79  ?  241 ALA E C   1 
ATOM   6227 O O   . ALA C 3 242 ? 45.505  125.408 101.884 1.00 71.79  ?  241 ALA E O   1 
ATOM   6228 C CB  . ALA C 3 242 ? 44.529  122.809 100.163 1.00 71.79  ?  241 ALA E CB  1 
ATOM   6229 N N   . GLY C 3 243 ? 45.836  123.490 103.009 1.00 73.97  ?  242 GLY E N   1 
ATOM   6230 C CA  . GLY C 3 243 ? 45.726  124.120 104.310 1.00 73.97  ?  242 GLY E CA  1 
ATOM   6231 C C   . GLY C 3 243 ? 44.340  124.000 104.907 1.00 73.97  ?  242 GLY E C   1 
ATOM   6232 O O   . GLY C 3 243 ? 43.343  124.274 104.233 1.00 73.97  ?  242 GLY E O   1 
ATOM   6233 N N   . THR C 3 244 ? 44.261  123.591 106.172 1.00 76.38  ?  243 THR E N   1 
ATOM   6234 C CA  . THR C 3 244 ? 42.989  123.422 106.864 1.00 76.38  ?  243 THR E CA  1 
ATOM   6235 C C   . THR C 3 244 ? 42.785  124.574 107.839 1.00 76.38  ?  243 THR E C   1 
ATOM   6236 O O   . THR C 3 244 ? 43.676  124.882 108.636 1.00 76.38  ?  243 THR E O   1 
ATOM   6237 C CB  . THR C 3 244 ? 42.945  122.086 107.608 1.00 76.38  ?  243 THR E CB  1 
ATOM   6238 O OG1 . THR C 3 244 ? 43.141  121.012 106.680 1.00 76.38  ?  243 THR E OG1 1 
ATOM   6239 C CG2 . THR C 3 244 ? 41.607  121.906 108.313 1.00 76.38  ?  243 THR E CG2 1 
ATOM   6240 N N   . LYS C 3 245 ? 41.615  125.202 107.779 1.00 78.24  ?  244 LYS E N   1 
ATOM   6241 C CA  . LYS C 3 245 ? 41.317  126.376 108.586 1.00 78.24  ?  244 LYS E CA  1 
ATOM   6242 C C   . LYS C 3 245 ? 40.463  125.995 109.788 1.00 78.24  ?  244 LYS E C   1 
ATOM   6243 O O   . LYS C 3 245 ? 39.488  125.248 109.660 1.00 78.24  ?  244 LYS E O   1 
ATOM   6244 C CB  . LYS C 3 245 ? 40.595  127.436 107.751 1.00 78.24  ?  244 LYS E CB  1 
ATOM   6245 C CG  . LYS C 3 245 ? 40.333  128.739 108.490 1.00 78.24  ?  244 LYS E CG  1 
ATOM   6246 C CD  . LYS C 3 245 ? 39.658  129.761 107.590 1.00 78.24  ?  244 LYS E CD  1 
ATOM   6247 C CE  . LYS C 3 245 ? 39.417  131.072 108.319 1.00 78.24  ?  244 LYS E CE  1 
ATOM   6248 N NZ  . LYS C 3 245 ? 38.752  132.082 107.449 1.00 78.24  1  244 LYS E NZ  1 
ATOM   6249 N N   . LEU C 3 246 ? 40.836  126.515 110.956 1.00 77.88  ?  245 LEU E N   1 
ATOM   6250 C CA  . LEU C 3 246 ? 40.078  126.338 112.189 1.00 77.88  ?  245 LEU E CA  1 
ATOM   6251 C C   . LEU C 3 246 ? 39.703  127.713 112.720 1.00 77.88  ?  245 LEU E C   1 
ATOM   6252 O O   . LEU C 3 246 ? 40.580  128.554 112.947 1.00 77.88  ?  245 LEU E O   1 
ATOM   6253 C CB  . LEU C 3 246 ? 40.883  125.562 113.234 1.00 77.88  ?  245 LEU E CB  1 
ATOM   6254 C CG  . LEU C 3 246 ? 41.328  124.145 112.865 1.00 77.88  ?  245 LEU E CG  1 
ATOM   6255 C CD1 . LEU C 3 246 ? 41.995  123.478 114.058 1.00 77.88  ?  245 LEU E CD1 1 
ATOM   6256 C CD2 . LEU C 3 246 ? 40.156  123.310 112.373 1.00 77.88  ?  245 LEU E CD2 1 
ATOM   6257 N N   . GLU C 3 247 ? 38.407  127.937 112.915 1.00 80.72  ?  246 GLU E N   1 
ATOM   6258 C CA  . GLU C 3 247 ? 37.882  129.206 113.394 1.00 80.72  ?  246 GLU E CA  1 
ATOM   6259 C C   . GLU C 3 247 ? 37.106  128.987 114.687 1.00 80.72  ?  246 GLU E C   1 
ATOM   6260 O O   . GLU C 3 247 ? 36.860  127.855 115.112 1.00 80.72  ?  246 GLU E O   1 
ATOM   6261 C CB  . GLU C 3 247 ? 36.986  129.872 112.339 1.00 80.72  ?  246 GLU E CB  1 
ATOM   6262 C CG  . GLU C 3 247 ? 35.764  129.057 111.923 1.00 80.72  ?  246 GLU E CG  1 
ATOM   6263 C CD  . GLU C 3 247 ? 36.110  127.897 111.008 1.00 80.72  ?  246 GLU E CD  1 
ATOM   6264 O OE1 . GLU C 3 247 ? 37.309  127.702 110.719 1.00 80.72  ?  246 GLU E OE1 1 
ATOM   6265 O OE2 . GLU C 3 247 ? 35.182  127.180 110.578 1.00 80.72  ?  246 GLU E OE2 1 
ATOM   6266 N N   . LEU C 3 248 ? 36.721  130.094 115.313 1.00 81.79  ?  247 LEU E N   1 
ATOM   6267 C CA  . LEU C 3 248 ? 35.970  130.049 116.562 1.00 81.79  ?  247 LEU E CA  1 
ATOM   6268 C C   . LEU C 3 248 ? 34.644  129.321 116.369 1.00 81.79  ?  247 LEU E C   1 
ATOM   6269 O O   . LEU C 3 248 ? 34.134  129.225 115.253 1.00 81.79  ?  247 LEU E O   1 
ATOM   6270 C CB  . LEU C 3 248 ? 35.723  131.465 117.089 1.00 81.79  ?  247 LEU E CB  1 
ATOM   6271 C CG  . LEU C 3 248 ? 34.978  131.574 118.422 1.00 81.79  ?  247 LEU E CG  1 
ATOM   6272 C CD1 . LEU C 3 248 ? 35.768  130.912 119.541 1.00 81.79  ?  247 LEU E CD1 1 
ATOM   6273 C CD2 . LEU C 3 248 ? 34.691  133.030 118.755 1.00 81.79  ?  247 LEU E CD2 1 
ATOM   6274 N N   . THR D 4 6   ? 95.064  120.404 165.913 1.00 126.95 ?  5   THR G N   1 
ATOM   6275 C CA  . THR D 4 6   ? 94.433  119.068 166.116 1.00 126.95 ?  5   THR G CA  1 
ATOM   6276 C C   . THR D 4 6   ? 94.186  118.368 164.783 1.00 126.95 ?  5   THR G C   1 
ATOM   6277 O O   . THR D 4 6   ? 93.410  117.416 164.709 1.00 126.95 ?  5   THR G O   1 
ATOM   6278 C CB  . THR D 4 6   ? 93.096  119.185 166.873 1.00 126.95 ?  5   THR G CB  1 
ATOM   6279 O OG1 . THR D 4 6   ? 92.203  120.037 166.146 1.00 126.95 ?  5   THR G OG1 1 
ATOM   6280 C CG2 . THR D 4 6   ? 93.317  119.753 168.267 1.00 126.95 ?  5   THR G CG2 1 
ATOM   6281 N N   . ALA D 4 7   ? 94.855  118.847 163.731 1.00 126.26 ?  6   ALA G N   1 
ATOM   6282 C CA  . ALA D 4 7   ? 94.665  118.274 162.402 1.00 126.26 ?  6   ALA G CA  1 
ATOM   6283 C C   . ALA D 4 7   ? 94.929  116.773 162.405 1.00 126.26 ?  6   ALA G C   1 
ATOM   6284 O O   . ALA D 4 7   ? 94.165  115.994 161.823 1.00 126.26 ?  6   ALA G O   1 
ATOM   6285 C CB  . ALA D 4 7   ? 95.579  118.978 161.397 1.00 126.26 ?  6   ALA G CB  1 
ATOM   6286 N N   . SER D 4 8   ? 96.012  116.350 163.058 1.00 125.84 ?  7   SER G N   1 
ATOM   6287 C CA  . SER D 4 8   ? 96.346  114.930 163.105 1.00 125.84 ?  7   SER G CA  1 
ATOM   6288 C C   . SER D 4 8   ? 95.220  114.127 163.747 1.00 125.84 ?  7   SER G C   1 
ATOM   6289 O O   . SER D 4 8   ? 94.646  113.226 163.125 1.00 125.84 ?  7   SER G O   1 
ATOM   6290 C CB  . SER D 4 8   ? 97.657  114.729 163.868 1.00 125.84 ?  7   SER G CB  1 
ATOM   6291 O OG  . SER D 4 8   ? 97.551  115.208 165.197 1.00 125.84 ?  7   SER G OG  1 
ATOM   6292 N N   . ILE D 4 9   ? 94.894  114.441 165.003 1.00 125.19 ?  8   ILE G N   1 
ATOM   6293 C CA  . ILE D 4 9   ? 93.827  113.718 165.685 1.00 125.19 ?  8   ILE G CA  1 
ATOM   6294 C C   . ILE D 4 9   ? 92.491  113.955 164.993 1.00 125.19 ?  8   ILE G C   1 
ATOM   6295 O O   . ILE D 4 9   ? 91.612  113.086 165.017 1.00 125.19 ?  8   ILE G O   1 
ATOM   6296 C CB  . ILE D 4 9   ? 93.771  114.118 167.172 1.00 125.19 ?  8   ILE G CB  1 
ATOM   6297 C CG1 . ILE D 4 9   ? 93.502  115.618 167.321 1.00 125.19 ?  8   ILE G CG1 1 
ATOM   6298 C CG2 . ILE D 4 9   ? 95.069  113.736 167.868 1.00 125.19 ?  8   ILE G CG2 1 
ATOM   6299 C CD1 . ILE D 4 9   ? 93.390  116.075 168.762 1.00 125.19 ?  8   ILE G CD1 1 
ATOM   6300 N N   . ALA D 4 10  ? 92.316  115.115 164.358 1.00 124.58 ?  9   ALA G N   1 
ATOM   6301 C CA  . ALA D 4 10  ? 91.075  115.387 163.640 1.00 124.58 ?  9   ALA G CA  1 
ATOM   6302 C C   . ALA D 4 10  ? 90.865  114.378 162.517 1.00 124.58 ?  9   ALA G C   1 
ATOM   6303 O O   . ALA D 4 10  ? 89.835  113.695 162.459 1.00 124.58 ?  9   ALA G O   1 
ATOM   6304 C CB  . ALA D 4 10  ? 91.092  116.814 163.090 1.00 124.58 ?  9   ALA G CB  1 
ATOM   6305 N N   . GLN D 4 11  ? 91.835  114.275 161.605 1.00 123.11 ?  10  GLN G N   1 
ATOM   6306 C CA  . GLN D 4 11  ? 91.710  113.310 160.519 1.00 123.11 ?  10  GLN G CA  1 
ATOM   6307 C C   . GLN D 4 11  ? 91.709  111.881 161.046 1.00 123.11 ?  10  GLN G C   1 
ATOM   6308 O O   . GLN D 4 11  ? 91.061  111.006 160.460 1.00 123.11 ?  10  GLN G O   1 
ATOM   6309 C CB  . GLN D 4 11  ? 92.831  113.512 159.493 1.00 123.11 ?  10  GLN G CB  1 
ATOM   6310 C CG  . GLN D 4 11  ? 94.248  113.355 160.033 1.00 123.11 ?  10  GLN G CG  1 
ATOM   6311 C CD  . GLN D 4 11  ? 94.686  111.906 160.149 1.00 123.11 ?  10  GLN G CD  1 
ATOM   6312 O OE1 . GLN D 4 11  ? 94.057  111.007 159.590 1.00 123.11 ?  10  GLN G OE1 1 
ATOM   6313 N NE2 . GLN D 4 11  ? 95.772  111.673 160.877 1.00 123.11 ?  10  GLN G NE2 1 
ATOM   6314 N N   . ALA D 4 12  ? 92.405  111.626 162.157 1.00 121.85 ?  11  ALA G N   1 
ATOM   6315 C CA  . ALA D 4 12  ? 92.383  110.292 162.745 1.00 121.85 ?  11  ALA G CA  1 
ATOM   6316 C C   . ALA D 4 12  ? 90.968  109.901 163.152 1.00 121.85 ?  11  ALA G C   1 
ATOM   6317 O O   . ALA D 4 12  ? 90.477  108.828 162.785 1.00 121.85 ?  11  ALA G O   1 
ATOM   6318 C CB  . ALA D 4 12  ? 93.327  110.235 163.946 1.00 121.85 ?  11  ALA G CB  1 
ATOM   6319 N N   . ARG D 4 13  ? 90.291  110.768 163.910 1.00 121.10 ?  12  ARG G N   1 
ATOM   6320 C CA  . ARG D 4 13  ? 88.926  110.469 164.329 1.00 121.10 ?  12  ARG G CA  1 
ATOM   6321 C C   . ARG D 4 13  ? 87.968  110.456 163.145 1.00 121.10 ?  12  ARG G C   1 
ATOM   6322 O O   . ARG D 4 13  ? 87.000  109.687 163.145 1.00 121.10 ?  12  ARG G O   1 
ATOM   6323 C CB  . ARG D 4 13  ? 88.459  111.475 165.383 1.00 121.10 ?  12  ARG G CB  1 
ATOM   6324 C CG  . ARG D 4 13  ? 88.375  112.914 164.897 1.00 121.10 ?  12  ARG G CG  1 
ATOM   6325 C CD  . ARG D 4 13  ? 87.773  113.832 165.953 1.00 121.10 ?  12  ARG G CD  1 
ATOM   6326 N NE  . ARG D 4 13  ? 88.564  113.863 167.182 1.00 121.10 ?  12  ARG G NE  1 
ATOM   6327 C CZ  . ARG D 4 13  ? 88.376  113.060 168.226 1.00 121.10 ?  12  ARG G CZ  1 
ATOM   6328 N NH1 . ARG D 4 13  ? 87.418  112.142 168.211 1.00 121.10 1  12  ARG G NH1 1 
ATOM   6329 N NH2 . ARG D 4 13  ? 89.154  113.174 169.294 1.00 121.10 ?  12  ARG G NH2 1 
ATOM   6330 N N   . LYS D 4 14  ? 88.215  111.288 162.131 1.00 119.44 ?  13  LYS G N   1 
ATOM   6331 C CA  . LYS D 4 14  ? 87.380  111.248 160.934 1.00 119.44 ?  13  LYS G CA  1 
ATOM   6332 C C   . LYS D 4 14  ? 87.464  109.884 160.261 1.00 119.44 ?  13  LYS G C   1 
ATOM   6333 O O   . LYS D 4 14  ? 86.438  109.274 159.933 1.00 119.44 ?  13  LYS G O   1 
ATOM   6334 C CB  . LYS D 4 14  ? 87.794  112.356 159.964 1.00 119.44 ?  13  LYS G CB  1 
ATOM   6335 C CG  . LYS D 4 14  ? 87.417  113.767 160.410 1.00 119.44 ?  13  LYS G CG  1 
ATOM   6336 C CD  . LYS D 4 14  ? 85.907  113.983 160.485 1.00 119.44 ?  13  LYS G CD  1 
ATOM   6337 C CE  . LYS D 4 14  ? 85.233  113.824 159.130 1.00 119.44 ?  13  LYS G CE  1 
ATOM   6338 N NZ  . LYS D 4 14  ? 83.783  114.158 159.188 1.00 119.44 1  13  LYS G NZ  1 
ATOM   6339 N N   . LEU D 4 15  ? 88.684  109.385 160.048 1.00 116.82 ?  14  LEU G N   1 
ATOM   6340 C CA  . LEU D 4 15  ? 88.845  108.064 159.450 1.00 116.82 ?  14  LEU G CA  1 
ATOM   6341 C C   . LEU D 4 15  ? 88.291  106.970 160.353 1.00 116.82 ?  14  LEU G C   1 
ATOM   6342 O O   . LEU D 4 15  ? 87.753  105.973 159.858 1.00 116.82 ?  14  LEU G O   1 
ATOM   6343 C CB  . LEU D 4 15  ? 90.320  107.802 159.143 1.00 116.82 ?  14  LEU G CB  1 
ATOM   6344 C CG  . LEU D 4 15  ? 90.971  108.737 158.121 1.00 116.82 ?  14  LEU G CG  1 
ATOM   6345 C CD1 . LEU D 4 15  ? 92.450  108.416 157.974 1.00 116.82 ?  14  LEU G CD1 1 
ATOM   6346 C CD2 . LEU D 4 15  ? 90.267  108.649 156.774 1.00 116.82 ?  14  LEU G CD2 1 
ATOM   6347 N N   . VAL D 4 16  ? 88.403  107.138 161.672 1.00 114.47 ?  15  VAL G N   1 
ATOM   6348 C CA  . VAL D 4 16  ? 87.844  106.156 162.597 1.00 114.47 ?  15  VAL G CA  1 
ATOM   6349 C C   . VAL D 4 16  ? 86.333  106.070 162.421 1.00 114.47 ?  15  VAL G C   1 
ATOM   6350 O O   . VAL D 4 16  ? 85.766  104.980 162.273 1.00 114.47 ?  15  VAL G O   1 
ATOM   6351 C CB  . VAL D 4 16  ? 88.225  106.510 164.046 1.00 114.47 ?  15  VAL G CB  1 
ATOM   6352 C CG1 . VAL D 4 16  ? 87.479  105.621 165.033 1.00 114.47 ?  15  VAL G CG1 1 
ATOM   6353 C CG2 . VAL D 4 16  ? 89.729  106.385 164.244 1.00 114.47 ?  15  VAL G CG2 1 
ATOM   6354 N N   . GLU D 4 17  ? 85.659  107.222 162.438 1.00 111.11 ?  16  GLU G N   1 
ATOM   6355 C CA  . GLU D 4 17  ? 84.212  107.236 162.251 1.00 111.11 ?  16  GLU G CA  1 
ATOM   6356 C C   . GLU D 4 17  ? 83.822  106.718 160.874 1.00 111.11 ?  16  GLU G C   1 
ATOM   6357 O O   . GLU D 4 17  ? 82.785  106.058 160.731 1.00 111.11 ?  16  GLU G O   1 
ATOM   6358 C CB  . GLU D 4 17  ? 83.671  108.650 162.458 1.00 111.11 ?  16  GLU G CB  1 
ATOM   6359 C CG  . GLU D 4 17  ? 83.846  109.179 163.873 1.00 111.11 ?  16  GLU G CG  1 
ATOM   6360 C CD  . GLU D 4 17  ? 83.315  110.590 164.038 1.00 111.11 ?  16  GLU G CD  1 
ATOM   6361 O OE1 . GLU D 4 17  ? 82.816  111.158 163.045 1.00 111.11 ?  16  GLU G OE1 1 
ATOM   6362 O OE2 . GLU D 4 17  ? 83.398  111.130 165.161 1.00 111.11 ?  16  GLU G OE2 1 
ATOM   6363 N N   . GLN D 4 18  ? 84.633  107.000 159.852 1.00 103.36 ?  17  GLN G N   1 
ATOM   6364 C CA  . GLN D 4 18  ? 84.329  106.505 158.514 1.00 103.36 ?  17  GLN G CA  1 
ATOM   6365 C C   . GLN D 4 18  ? 84.392  104.983 158.472 1.00 103.36 ?  17  GLN G C   1 
ATOM   6366 O O   . GLN D 4 18  ? 83.479  104.324 157.959 1.00 103.36 ?  17  GLN G O   1 
ATOM   6367 C CB  . GLN D 4 18  ? 85.297  107.114 157.499 1.00 103.36 ?  17  GLN G CB  1 
ATOM   6368 C CG  . GLN D 4 18  ? 84.877  106.918 156.050 1.00 103.36 ?  17  GLN G CG  1 
ATOM   6369 C CD  . GLN D 4 18  ? 83.581  107.635 155.718 1.00 103.36 ?  17  GLN G CD  1 
ATOM   6370 O OE1 . GLN D 4 18  ? 82.622  107.022 155.250 1.00 103.36 ?  17  GLN G OE1 1 
ATOM   6371 N NE2 . GLN D 4 18  ? 83.549  108.941 155.958 1.00 103.36 ?  17  GLN G NE2 1 
ATOM   6372 N N   . LEU D 4 19  ? 85.469  104.406 159.007 1.00 107.17 ?  18  LEU G N   1 
ATOM   6373 C CA  . LEU D 4 19  ? 85.577  102.952 159.060 1.00 107.17 ?  18  LEU G CA  1 
ATOM   6374 C C   . LEU D 4 19  ? 84.453  102.350 159.893 1.00 107.17 ?  18  LEU G C   1 
ATOM   6375 O O   . LEU D 4 19  ? 83.940  101.272 159.571 1.00 107.17 ?  18  LEU G O   1 
ATOM   6376 C CB  . LEU D 4 19  ? 86.939  102.547 159.625 1.00 107.17 ?  18  LEU G CB  1 
ATOM   6377 C CG  . LEU D 4 19  ? 88.159  102.939 158.787 1.00 107.17 ?  18  LEU G CG  1 
ATOM   6378 C CD1 . LEU D 4 19  ? 89.443  102.605 159.529 1.00 107.17 ?  18  LEU G CD1 1 
ATOM   6379 C CD2 . LEU D 4 19  ? 88.131  102.251 157.430 1.00 107.17 ?  18  LEU G CD2 1 
ATOM   6380 N N   . LYS D 4 20  ? 84.051  103.035 160.966 1.00 104.78 ?  19  LYS G N   1 
ATOM   6381 C CA  . LYS D 4 20  ? 82.963  102.533 161.798 1.00 104.78 ?  19  LYS G CA  1 
ATOM   6382 C C   . LYS D 4 20  ? 81.658  102.481 161.014 1.00 104.78 ?  19  LYS G C   1 
ATOM   6383 O O   . LYS D 4 20  ? 80.989  101.442 160.965 1.00 104.78 ?  19  LYS G O   1 
ATOM   6384 C CB  . LYS D 4 20  ? 82.810  103.408 163.042 1.00 104.78 ?  19  LYS G CB  1 
ATOM   6385 C CG  . LYS D 4 20  ? 81.745  102.923 164.016 1.00 104.78 ?  19  LYS G CG  1 
ATOM   6386 C CD  . LYS D 4 20  ? 81.667  103.799 165.260 1.00 104.78 ?  19  LYS G CD  1 
ATOM   6387 C CE  . LYS D 4 20  ? 81.165  105.203 164.943 1.00 104.78 ?  19  LYS G CE  1 
ATOM   6388 N NZ  . LYS D 4 20  ? 79.821  105.194 164.301 1.00 104.78 1  19  LYS G NZ  1 
ATOM   6389 N N   . MET D 4 21  ? 81.278  103.599 160.391 1.00 101.25 ?  20  MET G N   1 
ATOM   6390 C CA  . MET D 4 21  ? 80.040  103.634 159.621 1.00 101.25 ?  20  MET G CA  1 
ATOM   6391 C C   . MET D 4 21  ? 80.089  102.714 158.408 1.00 101.25 ?  20  MET G C   1 
ATOM   6392 O O   . MET D 4 21  ? 79.034  102.274 157.939 1.00 101.25 ?  20  MET G O   1 
ATOM   6393 C CB  . MET D 4 21  ? 79.735  105.066 159.176 1.00 101.25 ?  20  MET G CB  1 
ATOM   6394 C CG  . MET D 4 21  ? 80.774  105.665 158.247 1.00 101.25 ?  20  MET G CG  1 
ATOM   6395 S SD  . MET D 4 21  ? 80.478  107.407 157.883 1.00 101.25 ?  20  MET G SD  1 
ATOM   6396 C CE  . MET D 4 21  ? 78.877  107.325 157.085 1.00 101.25 ?  20  MET G CE  1 
ATOM   6397 N N   . GLU D 4 22  ? 81.282  102.412 157.890 1.00 96.57  ?  21  GLU G N   1 
ATOM   6398 C CA  . GLU D 4 22  ? 81.384  101.460 156.789 1.00 96.57  ?  21  GLU G CA  1 
ATOM   6399 C C   . GLU D 4 22  ? 81.221  100.025 157.277 1.00 96.57  ?  21  GLU G C   1 
ATOM   6400 O O   . GLU D 4 22  ? 80.597  99.204  156.596 1.00 96.57  ?  21  GLU G O   1 
ATOM   6401 C CB  . GLU D 4 22  ? 82.724  101.626 156.072 1.00 96.57  ?  21  GLU G CB  1 
ATOM   6402 C CG  . GLU D 4 22  ? 82.831  102.892 155.238 1.00 96.57  ?  21  GLU G CG  1 
ATOM   6403 C CD  . GLU D 4 22  ? 84.200  103.060 154.610 1.00 96.57  ?  21  GLU G CD  1 
ATOM   6404 O OE1 . GLU D 4 22  ? 85.067  102.189 154.830 1.00 96.57  ?  21  GLU G OE1 1 
ATOM   6405 O OE2 . GLU D 4 22  ? 84.410  104.063 153.896 1.00 96.57  ?  21  GLU G OE2 1 
ATOM   6406 N N   . ALA D 4 23  ? 81.774  99.706  158.449 1.00 99.36  ?  22  ALA G N   1 
ATOM   6407 C CA  . ALA D 4 23  ? 81.643  98.355  158.983 1.00 99.36  ?  22  ALA G CA  1 
ATOM   6408 C C   . ALA D 4 23  ? 80.194  98.019  159.313 1.00 99.36  ?  22  ALA G C   1 
ATOM   6409 O O   . ALA D 4 23  ? 79.795  96.853  159.223 1.00 99.36  ?  22  ALA G O   1 
ATOM   6410 C CB  . ALA D 4 23  ? 82.518  98.195  160.226 1.00 99.36  ?  22  ALA G CB  1 
ATOM   6411 N N   . ASN D 4 24  ? 79.396  99.020  159.693 1.00 99.61  ?  23  ASN G N   1 
ATOM   6412 C CA  . ASN D 4 24  ? 77.998  98.774  160.026 1.00 99.61  ?  23  ASN G CA  1 
ATOM   6413 C C   . ASN D 4 24  ? 77.178  98.356  158.813 1.00 99.61  ?  23  ASN G C   1 
ATOM   6414 O O   . ASN D 4 24  ? 76.078  97.818  158.981 1.00 99.61  ?  23  ASN G O   1 
ATOM   6415 C CB  . ASN D 4 24  ? 77.384  100.024 160.658 1.00 99.61  ?  23  ASN G CB  1 
ATOM   6416 C CG  . ASN D 4 24  ? 78.100  100.448 161.925 1.00 99.61  ?  23  ASN G CG  1 
ATOM   6417 O OD1 . ASN D 4 24  ? 78.646  99.618  162.651 1.00 99.61  ?  23  ASN G OD1 1 
ATOM   6418 N ND2 . ASN D 4 24  ? 78.101  101.748 162.196 1.00 99.61  ?  23  ASN G ND2 1 
ATOM   6419 N N   . ILE D 4 25  ? 77.682  98.588  157.600 1.00 93.50  ?  24  ILE G N   1 
ATOM   6420 C CA  . ILE D 4 25  ? 76.943  98.220  156.400 1.00 93.50  ?  24  ILE G CA  1 
ATOM   6421 C C   . ILE D 4 25  ? 76.916  96.704  156.263 1.00 93.50  ?  24  ILE G C   1 
ATOM   6422 O O   . ILE D 4 25  ? 77.908  96.016  156.543 1.00 93.50  ?  24  ILE G O   1 
ATOM   6423 C CB  . ILE D 4 25  ? 77.570  98.878  155.159 1.00 93.50  ?  24  ILE G CB  1 
ATOM   6424 C CG1 . ILE D 4 25  ? 77.634  100.401 155.328 1.00 93.50  ?  24  ILE G CG1 1 
ATOM   6425 C CG2 . ILE D 4 25  ? 76.784  98.511  153.907 1.00 93.50  ?  24  ILE G CG2 1 
ATOM   6426 C CD1 . ILE D 4 25  ? 76.286  101.064 155.546 1.00 93.50  ?  24  ILE G CD1 1 
ATOM   6427 N N   . ASP D 4 26  ? 75.776  96.175  155.829 1.00 91.20  ?  25  ASP G N   1 
ATOM   6428 C CA  . ASP D 4 26  ? 75.633  94.737  155.663 1.00 91.20  ?  25  ASP G CA  1 
ATOM   6429 C C   . ASP D 4 26  ? 76.493  94.241  154.506 1.00 91.20  ?  25  ASP G C   1 
ATOM   6430 O O   . ASP D 4 26  ? 76.742  94.956  153.532 1.00 91.20  ?  25  ASP G O   1 
ATOM   6431 C CB  . ASP D 4 26  ? 74.169  94.370  155.420 1.00 91.20  ?  25  ASP G CB  1 
ATOM   6432 C CG  . ASP D 4 26  ? 73.580  95.080  154.216 1.00 91.20  ?  25  ASP G CG  1 
ATOM   6433 O OD1 . ASP D 4 26  ? 74.276  95.931  153.624 1.00 91.20  ?  25  ASP G OD1 1 
ATOM   6434 O OD2 . ASP D 4 26  ? 72.419  94.786  153.861 1.00 91.20  ?  25  ASP G OD2 1 
ATOM   6435 N N   . ARG D 4 27  ? 76.951  92.996  154.624 1.00 88.19  ?  26  ARG G N   1 
ATOM   6436 C CA  . ARG D 4 27  ? 77.789  92.368  153.605 1.00 88.19  ?  26  ARG G CA  1 
ATOM   6437 C C   . ARG D 4 27  ? 77.372  90.909  153.477 1.00 88.19  ?  26  ARG G C   1 
ATOM   6438 O O   . ARG D 4 27  ? 77.629  90.107  154.380 1.00 88.19  ?  26  ARG G O   1 
ATOM   6439 C CB  . ARG D 4 27  ? 79.272  92.483  153.958 1.00 88.19  ?  26  ARG G CB  1 
ATOM   6440 C CG  . ARG D 4 27  ? 79.825  93.894  153.840 1.00 88.19  ?  26  ARG G CG  1 
ATOM   6441 C CD  . ARG D 4 27  ? 81.296  93.951  154.219 1.00 88.19  ?  26  ARG G CD  1 
ATOM   6442 N NE  . ARG D 4 27  ? 81.504  93.751  155.650 1.00 88.19  ?  26  ARG G NE  1 
ATOM   6443 C CZ  . ARG D 4 27  ? 81.419  94.713  156.565 1.00 88.19  ?  26  ARG G CZ  1 
ATOM   6444 N NH1 . ARG D 4 27  ? 81.126  95.957  156.207 1.00 88.19  1  26  ARG G NH1 1 
ATOM   6445 N NH2 . ARG D 4 27  ? 81.627  94.430  157.844 1.00 88.19  ?  26  ARG G NH2 1 
ATOM   6446 N N   . ILE D 4 28  ? 76.733  90.569  152.359 1.00 81.39  ?  27  ILE G N   1 
ATOM   6447 C CA  . ILE D 4 28  ? 76.315  89.193  152.123 1.00 81.39  ?  27  ILE G CA  1 
ATOM   6448 C C   . ILE D 4 28  ? 77.472  88.399  151.523 1.00 81.39  ?  27  ILE G C   1 
ATOM   6449 O O   . ILE D 4 28  ? 78.459  88.952  151.032 1.00 81.39  ?  27  ILE G O   1 
ATOM   6450 C CB  . ILE D 4 28  ? 75.071  89.138  151.218 1.00 81.39  ?  27  ILE G CB  1 
ATOM   6451 C CG1 . ILE D 4 28  ? 75.366  89.762  149.850 1.00 81.39  ?  27  ILE G CG1 1 
ATOM   6452 C CG2 . ILE D 4 28  ? 73.903  89.849  151.886 1.00 81.39  ?  27  ILE G CG2 1 
ATOM   6453 C CD1 . ILE D 4 28  ? 74.209  89.678  148.877 1.00 81.39  ?  27  ILE G CD1 1 
ATOM   6454 N N   . LYS D 4 29  ? 77.342  87.075  151.567 1.00 82.12  ?  28  LYS G N   1 
ATOM   6455 C CA  . LYS D 4 29  ? 78.380  86.208  151.036 1.00 82.12  ?  28  LYS G CA  1 
ATOM   6456 C C   . LYS D 4 29  ? 78.528  86.417  149.529 1.00 82.12  ?  28  LYS G C   1 
ATOM   6457 O O   . LYS D 4 29  ? 77.676  87.012  148.864 1.00 82.12  ?  28  LYS G O   1 
ATOM   6458 C CB  . LYS D 4 29  ? 78.064  84.745  151.345 1.00 82.12  ?  28  LYS G CB  1 
ATOM   6459 C CG  . LYS D 4 29  ? 76.822  84.213  150.645 1.00 82.12  ?  28  LYS G CG  1 
ATOM   6460 C CD  . LYS D 4 29  ? 76.431  82.832  151.157 1.00 82.12  ?  28  LYS G CD  1 
ATOM   6461 C CE  . LYS D 4 29  ? 77.546  81.814  150.961 1.00 82.12  ?  28  LYS G CE  1 
ATOM   6462 N NZ  . LYS D 4 29  ? 77.110  80.434  151.310 1.00 82.12  1  28  LYS G NZ  1 
ATOM   6463 N N   . VAL D 4 30  ? 79.639  85.911  148.991 1.00 81.04  ?  29  VAL G N   1 
ATOM   6464 C CA  . VAL D 4 30  ? 79.924  86.080  147.570 1.00 81.04  ?  29  VAL G CA  1 
ATOM   6465 C C   . VAL D 4 30  ? 79.070  85.172  146.695 1.00 81.04  ?  29  VAL G C   1 
ATOM   6466 O O   . VAL D 4 30  ? 78.847  85.490  145.520 1.00 81.04  ?  29  VAL G O   1 
ATOM   6467 C CB  . VAL D 4 30  ? 81.412  85.819  147.283 1.00 81.04  ?  29  VAL G CB  1 
ATOM   6468 C CG1 . VAL D 4 30  ? 81.708  85.989  145.799 1.00 81.04  ?  29  VAL G CG1 1 
ATOM   6469 C CG2 . VAL D 4 30  ? 82.284  86.748  148.113 1.00 81.04  ?  29  VAL G CG2 1 
ATOM   6470 N N   . SER D 4 31  ? 78.585  84.050  147.230 1.00 80.74  ?  30  SER G N   1 
ATOM   6471 C CA  . SER D 4 31  ? 77.810  83.118  146.417 1.00 80.74  ?  30  SER G CA  1 
ATOM   6472 C C   . SER D 4 31  ? 76.528  83.766  145.910 1.00 80.74  ?  30  SER G C   1 
ATOM   6473 O O   . SER D 4 31  ? 76.202  83.680  144.720 1.00 80.74  ?  30  SER G O   1 
ATOM   6474 C CB  . SER D 4 31  ? 77.493  81.859  147.225 1.00 80.74  ?  30  SER G CB  1 
ATOM   6475 O OG  . SER D 4 31  ? 76.798  80.909  146.436 1.00 80.74  ?  30  SER G OG  1 
ATOM   6476 N N   . LYS D 4 32  ? 75.781  84.416  146.805 1.00 79.78  ?  31  LYS G N   1 
ATOM   6477 C CA  . LYS D 4 32  ? 74.523  85.038  146.403 1.00 79.78  ?  31  LYS G CA  1 
ATOM   6478 C C   . LYS D 4 32  ? 74.763  86.169  145.411 1.00 79.78  ?  31  LYS G C   1 
ATOM   6479 O O   . LYS D 4 32  ? 74.010  86.326  144.442 1.00 79.78  ?  31  LYS G O   1 
ATOM   6480 C CB  . LYS D 4 32  ? 73.778  85.551  147.634 1.00 79.78  ?  31  LYS G CB  1 
ATOM   6481 C CG  . LYS D 4 32  ? 72.373  86.055  147.345 1.00 79.78  ?  31  LYS G CG  1 
ATOM   6482 C CD  . LYS D 4 32  ? 71.663  86.480  148.620 1.00 79.78  ?  31  LYS G CD  1 
ATOM   6483 C CE  . LYS D 4 32  ? 70.230  86.903  148.345 1.00 79.78  ?  31  LYS G CE  1 
ATOM   6484 N NZ  . LYS D 4 32  ? 69.530  87.345  149.583 1.00 79.78  1  31  LYS G NZ  1 
ATOM   6485 N N   . ALA D 4 33  ? 75.806  86.970  145.635 1.00 77.78  ?  32  ALA G N   1 
ATOM   6486 C CA  . ALA D 4 33  ? 76.114  88.059  144.715 1.00 77.78  ?  32  ALA G CA  1 
ATOM   6487 C C   . ALA D 4 33  ? 76.465  87.521  143.333 1.00 77.78  ?  32  ALA G C   1 
ATOM   6488 O O   . ALA D 4 33  ? 75.994  88.038  142.313 1.00 77.78  ?  32  ALA G O   1 
ATOM   6489 C CB  . ALA D 4 33  ? 77.258  88.906  145.271 1.00 77.78  ?  32  ALA G CB  1 
ATOM   6490 N N   . ALA D 4 34  ? 77.299  86.480  143.280 1.00 78.09  ?  33  ALA G N   1 
ATOM   6491 C CA  . ALA D 4 34  ? 77.664  85.892  141.996 1.00 78.09  ?  33  ALA G CA  1 
ATOM   6492 C C   . ALA D 4 34  ? 76.446  85.305  141.296 1.00 78.09  ?  33  ALA G C   1 
ATOM   6493 O O   . ALA D 4 34  ? 76.293  85.445  140.076 1.00 78.09  ?  33  ALA G O   1 
ATOM   6494 C CB  . ALA D 4 34  ? 78.736  84.822  142.196 1.00 78.09  ?  33  ALA G CB  1 
ATOM   6495 N N   . ALA D 4 35  ? 75.566  84.642  142.051 1.00 78.42  ?  34  ALA G N   1 
ATOM   6496 C CA  . ALA D 4 35  ? 74.358  84.084  141.452 1.00 78.42  ?  34  ALA G CA  1 
ATOM   6497 C C   . ALA D 4 35  ? 73.470  85.183  140.887 1.00 78.42  ?  34  ALA G C   1 
ATOM   6498 O O   . ALA D 4 35  ? 72.930  85.050  139.782 1.00 78.42  ?  34  ALA G O   1 
ATOM   6499 C CB  . ALA D 4 35  ? 73.596  83.256  142.486 1.00 78.42  ?  34  ALA G CB  1 
ATOM   6500 N N   . ASP D 4 36  ? 73.308  86.282  141.628 1.00 77.18  ?  35  ASP G N   1 
ATOM   6501 C CA  . ASP D 4 36  ? 72.488  87.386  141.142 1.00 77.18  ?  35  ASP G CA  1 
ATOM   6502 C C   . ASP D 4 36  ? 73.095  88.006  139.890 1.00 77.18  ?  35  ASP G C   1 
ATOM   6503 O O   . ASP D 4 36  ? 72.376  88.338  138.940 1.00 77.18  ?  35  ASP G O   1 
ATOM   6504 C CB  . ASP D 4 36  ? 72.325  88.437  142.240 1.00 77.18  ?  35  ASP G CB  1 
ATOM   6505 C CG  . ASP D 4 36  ? 71.244  89.455  141.923 1.00 77.18  ?  35  ASP G CG  1 
ATOM   6506 O OD1 . ASP D 4 36  ? 71.000  89.722  140.728 1.00 77.18  ?  35  ASP G OD1 1 
ATOM   6507 O OD2 . ASP D 4 36  ? 70.636  89.990  142.874 1.00 77.18  ?  35  ASP G OD2 1 
ATOM   6508 N N   . LEU D 4 37  ? 74.420  88.171  139.870 1.00 74.17  ?  36  LEU G N   1 
ATOM   6509 C CA  . LEU D 4 37  ? 75.076  88.725  138.690 1.00 74.17  ?  36  LEU G CA  1 
ATOM   6510 C C   . LEU D 4 37  ? 74.878  87.817  137.482 1.00 74.17  ?  36  LEU G C   1 
ATOM   6511 O O   . LEU D 4 37  ? 74.564  88.285  136.382 1.00 74.17  ?  36  LEU G O   1 
ATOM   6512 C CB  . LEU D 4 37  ? 76.565  88.935  138.966 1.00 74.17  ?  36  LEU G CB  1 
ATOM   6513 C CG  . LEU D 4 37  ? 76.928  90.017  139.986 1.00 74.17  ?  36  LEU G CG  1 
ATOM   6514 C CD1 . LEU D 4 37  ? 78.431  90.052  140.211 1.00 74.17  ?  36  LEU G CD1 1 
ATOM   6515 C CD2 . LEU D 4 37  ? 76.423  91.378  139.539 1.00 74.17  ?  36  LEU G CD2 1 
ATOM   6516 N N   . MET D 4 38  ? 75.059  86.507  137.671 1.00 77.09  ?  37  MET G N   1 
ATOM   6517 C CA  . MET D 4 38  ? 74.881  85.573  136.565 1.00 77.09  ?  37  MET G CA  1 
ATOM   6518 C C   . MET D 4 38  ? 73.441  85.581  136.067 1.00 77.09  ?  37  MET G C   1 
ATOM   6519 O O   . MET D 4 38  ? 73.194  85.515  134.857 1.00 77.09  ?  37  MET G O   1 
ATOM   6520 C CB  . MET D 4 38  ? 75.292  84.166  136.999 1.00 77.09  ?  37  MET G CB  1 
ATOM   6521 C CG  . MET D 4 38  ? 75.203  83.124  135.894 1.00 77.09  ?  37  MET G CG  1 
ATOM   6522 S SD  . MET D 4 38  ? 75.870  81.521  136.383 1.00 77.09  ?  37  MET G SD  1 
ATOM   6523 C CE  . MET D 4 38  ? 74.798  81.105  137.756 1.00 77.09  ?  37  MET G CE  1 
ATOM   6524 N N   . ALA D 4 39  ? 72.476  85.666  136.985 1.00 74.99  ?  38  ALA G N   1 
ATOM   6525 C CA  . ALA D 4 39  ? 71.075  85.707  136.582 1.00 74.99  ?  38  ALA G CA  1 
ATOM   6526 C C   . ALA D 4 39  ? 70.773  86.972  135.789 1.00 74.99  ?  38  ALA G C   1 
ATOM   6527 O O   . ALA D 4 39  ? 70.107  86.921  134.748 1.00 74.99  ?  38  ALA G O   1 
ATOM   6528 C CB  . ALA D 4 39  ? 70.173  85.613  137.812 1.00 74.99  ?  38  ALA G CB  1 
ATOM   6529 N N   . TYR D 4 40  ? 71.256  88.121  136.266 1.00 71.53  ?  39  TYR G N   1 
ATOM   6530 C CA  . TYR D 4 40  ? 71.027  89.369  135.545 1.00 71.53  ?  39  TYR G CA  1 
ATOM   6531 C C   . TYR D 4 40  ? 71.682  89.335  134.171 1.00 71.53  ?  39  TYR G C   1 
ATOM   6532 O O   . TYR D 4 40  ? 71.133  89.868  133.199 1.00 71.53  ?  39  TYR G O   1 
ATOM   6533 C CB  . TYR D 4 40  ? 71.551  90.551  136.360 1.00 71.53  ?  39  TYR G CB  1 
ATOM   6534 C CG  . TYR D 4 40  ? 71.296  91.895  135.715 1.00 71.53  ?  39  TYR G CG  1 
ATOM   6535 C CD1 . TYR D 4 40  ? 70.109  92.579  135.937 1.00 71.53  ?  39  TYR G CD1 1 
ATOM   6536 C CD2 . TYR D 4 40  ? 72.242  92.479  134.882 1.00 71.53  ?  39  TYR G CD2 1 
ATOM   6537 C CE1 . TYR D 4 40  ? 69.870  93.807  135.349 1.00 71.53  ?  39  TYR G CE1 1 
ATOM   6538 C CE2 . TYR D 4 40  ? 72.012  93.706  134.289 1.00 71.53  ?  39  TYR G CE2 1 
ATOM   6539 C CZ  . TYR D 4 40  ? 70.824  94.365  134.526 1.00 71.53  ?  39  TYR G CZ  1 
ATOM   6540 O OH  . TYR D 4 40  ? 70.591  95.587  133.938 1.00 71.53  ?  39  TYR G OH  1 
ATOM   6541 N N   . CYS D 4 41  ? 72.858  88.713  134.068 1.00 73.68  ?  40  CYS G N   1 
ATOM   6542 C CA  . CYS D 4 41  ? 73.531  88.617  132.777 1.00 73.68  ?  40  CYS G CA  1 
ATOM   6543 C C   . CYS D 4 41  ? 72.754  87.720  131.821 1.00 73.68  ?  40  CYS G C   1 
ATOM   6544 O O   . CYS D 4 41  ? 72.564  88.063  130.648 1.00 73.68  ?  40  CYS G O   1 
ATOM   6545 C CB  . CYS D 4 41  ? 74.955  88.096  132.969 1.00 73.68  ?  40  CYS G CB  1 
ATOM   6546 S SG  . CYS D 4 41  ? 76.034  89.207  133.902 1.00 73.68  ?  40  CYS G SG  1 
ATOM   6547 N N   . GLU D 4 42  ? 72.297  86.563  132.305 1.00 75.69  ?  41  GLU G N   1 
ATOM   6548 C CA  . GLU D 4 42  ? 71.531  85.654  131.461 1.00 75.69  ?  41  GLU G CA  1 
ATOM   6549 C C   . GLU D 4 42  ? 70.158  86.209  131.109 1.00 75.69  ?  41  GLU G C   1 
ATOM   6550 O O   . GLU D 4 42  ? 69.562  85.769  130.120 1.00 75.69  ?  41  GLU G O   1 
ATOM   6551 C CB  . GLU D 4 42  ? 71.377  84.299  132.155 1.00 75.69  ?  41  GLU G CB  1 
ATOM   6552 C CG  . GLU D 4 42  ? 72.680  83.535  132.328 1.00 75.69  ?  41  GLU G CG  1 
ATOM   6553 C CD  . GLU D 4 42  ? 73.255  83.053  131.010 1.00 75.69  ?  41  GLU G CD  1 
ATOM   6554 O OE1 . GLU D 4 42  ? 72.597  83.244  129.965 1.00 75.69  ?  41  GLU G OE1 1 
ATOM   6555 O OE2 . GLU D 4 42  ? 74.365  82.481  131.018 1.00 75.69  ?  41  GLU G OE2 1 
ATOM   6556 N N   . ALA D 4 43  ? 69.643  87.161  131.890 1.00 73.78  ?  42  ALA G N   1 
ATOM   6557 C CA  . ALA D 4 43  ? 68.330  87.724  131.593 1.00 73.78  ?  42  ALA G CA  1 
ATOM   6558 C C   . ALA D 4 43  ? 68.377  88.624  130.365 1.00 73.78  ?  42  ALA G C   1 
ATOM   6559 O O   . ALA D 4 43  ? 67.465  88.593  129.531 1.00 73.78  ?  42  ALA G O   1 
ATOM   6560 C CB  . ALA D 4 43  ? 67.807  88.496  132.803 1.00 73.78  ?  42  ALA G CB  1 
ATOM   6561 N N   . HIS D 4 44  ? 69.431  89.431  130.234 1.00 72.28  ?  43  HIS G N   1 
ATOM   6562 C CA  . HIS D 4 44  ? 69.583  90.357  129.121 1.00 72.28  ?  43  HIS G CA  1 
ATOM   6563 C C   . HIS D 4 44  ? 70.534  89.831  128.051 1.00 72.28  ?  43  HIS G C   1 
ATOM   6564 O O   . HIS D 4 44  ? 71.105  90.624  127.295 1.00 72.28  ?  43  HIS G O   1 
ATOM   6565 C CB  . HIS D 4 44  ? 70.068  91.715  129.632 1.00 72.28  ?  43  HIS G CB  1 
ATOM   6566 C CG  . HIS D 4 44  ? 69.170  92.329  130.660 1.00 72.28  ?  43  HIS G CG  1 
ATOM   6567 N ND1 . HIS D 4 44  ? 68.120  93.160  130.331 1.00 72.28  ?  43  HIS G ND1 1 
ATOM   6568 C CD2 . HIS D 4 44  ? 69.164  92.234  132.011 1.00 72.28  ?  43  HIS G CD2 1 
ATOM   6569 C CE1 . HIS D 4 44  ? 67.507  93.550  131.434 1.00 72.28  ?  43  HIS G CE1 1 
ATOM   6570 N NE2 . HIS D 4 44  ? 68.121  93.002  132.467 1.00 72.28  ?  43  HIS G NE2 1 
ATOM   6571 N N   . ALA D 4 45  ? 70.714  88.511  127.972 1.00 71.66  ?  44  ALA G N   1 
ATOM   6572 C CA  . ALA D 4 45  ? 71.630  87.950  126.984 1.00 71.66  ?  44  ALA G CA  1 
ATOM   6573 C C   . ALA D 4 45  ? 71.183  88.279  125.565 1.00 71.66  ?  44  ALA G C   1 
ATOM   6574 O O   . ALA D 4 45  ? 72.005  88.643  124.716 1.00 71.66  ?  44  ALA G O   1 
ATOM   6575 C CB  . ALA D 4 45  ? 71.742  86.438  127.173 1.00 71.66  ?  44  ALA G CB  1 
ATOM   6576 N N   . LYS D 4 46  ? 69.882  88.158  125.289 1.00 72.53  ?  45  LYS G N   1 
ATOM   6577 C CA  . LYS D 4 46  ? 69.378  88.430  123.948 1.00 72.53  ?  45  LYS G CA  1 
ATOM   6578 C C   . LYS D 4 46  ? 69.365  89.918  123.623 1.00 72.53  ?  45  LYS G C   1 
ATOM   6579 O O   . LYS D 4 46  ? 69.408  90.280  122.442 1.00 72.53  ?  45  LYS G O   1 
ATOM   6580 C CB  . LYS D 4 46  ? 67.970  87.856  123.791 1.00 72.53  ?  45  LYS G CB  1 
ATOM   6581 C CG  . LYS D 4 46  ? 67.902  86.343  123.923 1.00 72.53  ?  45  LYS G CG  1 
ATOM   6582 C CD  . LYS D 4 46  ? 66.486  85.830  123.715 1.00 72.53  ?  45  LYS G CD  1 
ATOM   6583 C CE  . LYS D 4 46  ? 66.418  84.316  123.836 1.00 72.53  ?  45  LYS G CE  1 
ATOM   6584 N NZ  . LYS D 4 46  ? 67.259  83.631  122.816 1.00 72.53  1  45  LYS G NZ  1 
ATOM   6585 N N   . GLU D 4 47  ? 69.307  90.784  124.635 1.00 72.13  ?  46  GLU G N   1 
ATOM   6586 C CA  . GLU D 4 47  ? 69.279  92.225  124.433 1.00 72.13  ?  46  GLU G CA  1 
ATOM   6587 C C   . GLU D 4 47  ? 70.674  92.840  124.402 1.00 72.13  ?  46  GLU G C   1 
ATOM   6588 O O   . GLU D 4 47  ? 70.818  94.039  124.666 1.00 72.13  ?  46  GLU G O   1 
ATOM   6589 C CB  . GLU D 4 47  ? 68.439  92.891  125.526 1.00 72.13  ?  46  GLU G CB  1 
ATOM   6590 C CG  . GLU D 4 47  ? 66.993  92.426  125.564 1.00 72.13  ?  46  GLU G CG  1 
ATOM   6591 C CD  . GLU D 4 47  ? 66.188  93.113  126.650 1.00 72.13  ?  46  GLU G CD  1 
ATOM   6592 O OE1 . GLU D 4 47  ? 66.762  93.953  127.375 1.00 72.13  ?  46  GLU G OE1 1 
ATOM   6593 O OE2 . GLU D 4 47  ? 64.983  92.813  126.779 1.00 72.13  ?  46  GLU G OE2 1 
ATOM   6594 N N   . ASP D 4 48  ? 71.699  92.050  124.084 1.00 68.91  ?  47  ASP G N   1 
ATOM   6595 C CA  . ASP D 4 48  ? 73.081  92.522  124.025 1.00 68.91  ?  47  ASP G CA  1 
ATOM   6596 C C   . ASP D 4 48  ? 73.641  92.184  122.650 1.00 68.91  ?  47  ASP G C   1 
ATOM   6597 O O   . ASP D 4 48  ? 74.194  91.094  122.444 1.00 68.91  ?  47  ASP G O   1 
ATOM   6598 C CB  . ASP D 4 48  ? 73.926  91.898  125.134 1.00 68.91  ?  47  ASP G CB  1 
ATOM   6599 C CG  . ASP D 4 48  ? 75.339  92.447  125.172 1.00 68.91  ?  47  ASP G CG  1 
ATOM   6600 O OD1 . ASP D 4 48  ? 75.647  93.362  124.379 1.00 68.91  ?  47  ASP G OD1 1 
ATOM   6601 O OD2 . ASP D 4 48  ? 76.143  91.963  125.996 1.00 68.91  ?  47  ASP G OD2 1 
ATOM   6602 N N   . PRO D 4 49  ? 73.510  93.091  121.678 1.00 66.03  ?  48  PRO G N   1 
ATOM   6603 C CA  . PRO D 4 49  ? 74.066  92.808  120.344 1.00 66.03  ?  48  PRO G CA  1 
ATOM   6604 C C   . PRO D 4 49  ? 75.544  92.467  120.368 1.00 66.03  ?  48  PRO G C   1 
ATOM   6605 O O   . PRO D 4 49  ? 76.011  91.716  119.502 1.00 66.03  ?  48  PRO G O   1 
ATOM   6606 C CB  . PRO D 4 49  ? 73.796  94.107  119.571 1.00 66.03  ?  48  PRO G CB  1 
ATOM   6607 C CG  . PRO D 4 49  ? 72.637  94.730  120.267 1.00 66.03  ?  48  PRO G CG  1 
ATOM   6608 C CD  . PRO D 4 49  ? 72.788  94.375  121.716 1.00 66.03  ?  48  PRO G CD  1 
ATOM   6609 N N   . LEU D 4 50  ? 76.298  92.995  121.334 1.00 65.04  ?  49  LEU G N   1 
ATOM   6610 C CA  . LEU D 4 50  ? 77.716  92.664  121.424 1.00 65.04  ?  49  LEU G CA  1 
ATOM   6611 C C   . LEU D 4 50  ? 77.914  91.207  121.820 1.00 65.04  ?  49  LEU G C   1 
ATOM   6612 O O   . LEU D 4 50  ? 78.822  90.537  121.313 1.00 65.04  ?  49  LEU G O   1 
ATOM   6613 C CB  . LEU D 4 50  ? 78.405  93.590  122.427 1.00 65.04  ?  49  LEU G CB  1 
ATOM   6614 C CG  . LEU D 4 50  ? 78.259  95.090  122.162 1.00 65.04  ?  49  LEU G CG  1 
ATOM   6615 C CD1 . LEU D 4 50  ? 78.906  95.890  123.280 1.00 65.04  ?  49  LEU G CD1 1 
ATOM   6616 C CD2 . LEU D 4 50  ? 78.858  95.465  120.815 1.00 65.04  ?  49  LEU G CD2 1 
ATOM   6617 N N   . LEU D 4 51  ? 77.075  90.698  122.724 1.00 68.61  ?  50  LEU G N   1 
ATOM   6618 C CA  . LEU D 4 51  ? 77.172  89.302  123.134 1.00 68.61  ?  50  LEU G CA  1 
ATOM   6619 C C   . LEU D 4 51  ? 76.548  88.379  122.094 1.00 68.61  ?  50  LEU G C   1 
ATOM   6620 O O   . LEU D 4 51  ? 77.159  87.386  121.687 1.00 68.61  ?  50  LEU G O   1 
ATOM   6621 C CB  . LEU D 4 51  ? 76.499  89.111  124.495 1.00 68.61  ?  50  LEU G CB  1 
ATOM   6622 C CG  . LEU D 4 51  ? 76.553  87.703  125.092 1.00 68.61  ?  50  LEU G CG  1 
ATOM   6623 C CD1 . LEU D 4 51  ? 77.988  87.289  125.371 1.00 68.61  ?  50  LEU G CD1 1 
ATOM   6624 C CD2 . LEU D 4 51  ? 75.716  87.631  126.359 1.00 68.61  ?  50  LEU G CD2 1 
ATOM   6625 N N   . THR D 4 52  ? 75.331  88.694  121.657 1.00 69.10  ?  51  THR G N   1 
ATOM   6626 C CA  . THR D 4 52  ? 74.633  87.904  120.648 1.00 69.10  ?  51  THR G CA  1 
ATOM   6627 C C   . THR D 4 52  ? 74.651  88.652  119.322 1.00 69.10  ?  51  THR G C   1 
ATOM   6628 O O   . THR D 4 52  ? 73.909  89.635  119.167 1.00 69.10  ?  51  THR G O   1 
ATOM   6629 C CB  . THR D 4 52  ? 73.193  87.626  121.082 1.00 69.10  ?  51  THR G CB  1 
ATOM   6630 O OG1 . THR D 4 52  ? 72.504  88.865  121.293 1.00 69.10  ?  51  THR G OG1 1 
ATOM   6631 C CG2 . THR D 4 52  ? 73.169  86.808  122.366 1.00 69.10  ?  51  THR G CG2 1 
ATOM   6632 N N   . PRO D 4 53  ? 75.467  88.247  118.348 1.00 69.21  ?  52  PRO G N   1 
ATOM   6633 C CA  . PRO D 4 53  ? 75.487  88.960  117.061 1.00 69.21  ?  52  PRO G CA  1 
ATOM   6634 C C   . PRO D 4 53  ? 74.106  88.998  116.425 1.00 69.21  ?  52  PRO G C   1 
ATOM   6635 O O   . PRO D 4 53  ? 73.535  87.963  116.072 1.00 69.21  ?  52  PRO G O   1 
ATOM   6636 C CB  . PRO D 4 53  ? 76.480  88.146  116.222 1.00 69.21  ?  52  PRO G CB  1 
ATOM   6637 C CG  . PRO D 4 53  ? 77.352  87.468  117.219 1.00 69.21  ?  52  PRO G CG  1 
ATOM   6638 C CD  . PRO D 4 53  ? 76.472  87.170  118.395 1.00 69.21  ?  52  PRO G CD  1 
ATOM   6639 N N   . VAL D 4 54  ? 73.570  90.206  116.282 1.00 68.63  ?  53  VAL G N   1 
ATOM   6640 C CA  . VAL D 4 54  ? 72.253  90.409  115.684 1.00 68.63  ?  53  VAL G CA  1 
ATOM   6641 C C   . VAL D 4 54  ? 72.402  90.430  114.167 1.00 68.63  ?  53  VAL G C   1 
ATOM   6642 O O   . VAL D 4 54  ? 73.490  90.736  113.658 1.00 68.63  ?  53  VAL G O   1 
ATOM   6643 C CB  . VAL D 4 54  ? 71.602  91.705  116.195 1.00 68.63  ?  53  VAL G CB  1 
ATOM   6644 C CG1 . VAL D 4 54  ? 71.407  91.642  117.703 1.00 68.63  ?  53  VAL G CG1 1 
ATOM   6645 C CG2 . VAL D 4 54  ? 72.439  92.919  115.809 1.00 68.63  ?  53  VAL G CG2 1 
ATOM   6646 N N   . PRO D 4 55  ? 71.353  90.115  113.408 1.00 69.75  ?  54  PRO G N   1 
ATOM   6647 C CA  . PRO D 4 55  ? 71.470  90.148  111.947 1.00 69.75  ?  54  PRO G CA  1 
ATOM   6648 C C   . PRO D 4 55  ? 71.715  91.561  111.438 1.00 69.75  ?  54  PRO G C   1 
ATOM   6649 O O   . PRO D 4 55  ? 71.510  92.553  112.140 1.00 69.75  ?  54  PRO G O   1 
ATOM   6650 C CB  . PRO D 4 55  ? 70.118  89.605  111.466 1.00 69.75  ?  54  PRO G CB  1 
ATOM   6651 C CG  . PRO D 4 55  ? 69.182  89.857  112.598 1.00 69.75  ?  54  PRO G CG  1 
ATOM   6652 C CD  . PRO D 4 55  ? 70.003  89.718  113.845 1.00 69.75  ?  54  PRO G CD  1 
ATOM   6653 N N   . ALA D 4 56  ? 72.166  91.640  110.183 1.00 68.83  ?  55  ALA G N   1 
ATOM   6654 C CA  . ALA D 4 56  ? 72.463  92.934  109.581 1.00 68.83  ?  55  ALA G CA  1 
ATOM   6655 C C   . ALA D 4 56  ? 71.219  93.796  109.416 1.00 68.83  ?  55  ALA G C   1 
ATOM   6656 O O   . ALA D 4 56  ? 71.342  95.007  109.199 1.00 68.83  ?  55  ALA G O   1 
ATOM   6657 C CB  . ALA D 4 56  ? 73.140  92.737  108.224 1.00 68.83  ?  55  ALA G CB  1 
ATOM   6658 N N   . SER D 4 57  ? 70.026  93.206  109.513 1.00 69.55  ?  56  SER G N   1 
ATOM   6659 C CA  . SER D 4 57  ? 68.795  93.972  109.369 1.00 69.55  ?  56  SER G CA  1 
ATOM   6660 C C   . SER D 4 57  ? 68.510  94.859  110.573 1.00 69.55  ?  56  SER G C   1 
ATOM   6661 O O   . SER D 4 57  ? 67.759  95.832  110.443 1.00 69.55  ?  56  SER G O   1 
ATOM   6662 C CB  . SER D 4 57  ? 67.613  93.026  109.142 1.00 69.55  ?  56  SER G CB  1 
ATOM   6663 O OG  . SER D 4 57  ? 67.459  92.134  110.232 1.00 69.55  ?  56  SER G OG  1 
ATOM   6664 N N   . GLU D 4 58  ? 69.086  94.549  111.733 1.00 70.14  ?  57  GLU G N   1 
ATOM   6665 C CA  . GLU D 4 58  ? 68.871  95.337  112.939 1.00 70.14  ?  57  GLU G CA  1 
ATOM   6666 C C   . GLU D 4 58  ? 69.953  96.384  113.169 1.00 70.14  ?  57  GLU G C   1 
ATOM   6667 O O   . GLU D 4 58  ? 69.763  97.272  114.007 1.00 70.14  ?  57  GLU G O   1 
ATOM   6668 C CB  . GLU D 4 58  ? 68.793  94.415  114.161 1.00 70.14  ?  57  GLU G CB  1 
ATOM   6669 C CG  . GLU D 4 58  ? 67.665  93.398  114.096 1.00 70.14  ?  57  GLU G CG  1 
ATOM   6670 C CD  . GLU D 4 58  ? 67.599  92.519  115.329 1.00 70.14  ?  57  GLU G CD  1 
ATOM   6671 O OE1 . GLU D 4 58  ? 68.415  92.726  116.252 1.00 70.14  ?  57  GLU G OE1 1 
ATOM   6672 O OE2 . GLU D 4 58  ? 66.732  91.622  115.376 1.00 70.14  ?  57  GLU G OE2 1 
ATOM   6673 N N   . ASN D 4 59  ? 71.071  96.305  112.455 1.00 67.69  ?  58  ASN G N   1 
ATOM   6674 C CA  . ASN D 4 59  ? 72.152  97.271  112.612 1.00 67.69  ?  58  ASN G CA  1 
ATOM   6675 C C   . ASN D 4 59  ? 71.963  98.453  111.667 1.00 67.69  ?  58  ASN G C   1 
ATOM   6676 O O   . ASN D 4 59  ? 71.009  99.220  111.801 1.00 67.69  ?  58  ASN G O   1 
ATOM   6677 C CB  . ASN D 4 59  ? 73.506  96.607  112.359 1.00 67.69  ?  58  ASN G CB  1 
ATOM   6678 C CG  . ASN D 4 59  ? 73.790  95.474  113.325 1.00 67.69  ?  58  ASN G CG  1 
ATOM   6679 O OD1 . ASN D 4 59  ? 73.331  95.488  114.468 1.00 67.69  ?  58  ASN G OD1 1 
ATOM   6680 N ND2 . ASN D 4 59  ? 74.550  94.484  112.871 1.00 67.69  ?  58  ASN G ND2 1 
ATOM   6681 N N   . THR E 5 32  ? 134.483 87.632  72.002  1.00 90.04  ?  32  THR R N   1 
ATOM   6682 C CA  . THR E 5 32  ? 133.143 87.264  72.541  1.00 90.04  ?  32  THR R CA  1 
ATOM   6683 C C   . THR E 5 32  ? 133.169 87.214  74.065  1.00 90.04  ?  32  THR R C   1 
ATOM   6684 O O   . THR E 5 32  ? 134.080 86.640  74.661  1.00 90.04  ?  32  THR R O   1 
ATOM   6685 C CB  . THR E 5 32  ? 132.672 85.901  71.999  1.00 90.04  ?  32  THR R CB  1 
ATOM   6686 O OG1 . THR E 5 32  ? 133.619 84.887  72.355  1.00 90.04  ?  32  THR R OG1 1 
ATOM   6687 C CG2 . THR E 5 32  ? 132.524 85.949  70.486  1.00 90.04  ?  32  THR R CG2 1 
ATOM   6688 N N   . ILE E 5 33  ? 132.158 87.823  74.690  1.00 90.74  ?  33  ILE R N   1 
ATOM   6689 C CA  . ILE E 5 33  ? 132.060 87.862  76.146  1.00 90.74  ?  33  ILE R CA  1 
ATOM   6690 C C   . ILE E 5 33  ? 131.003 86.906  76.685  1.00 90.74  ?  33  ILE R C   1 
ATOM   6691 O O   . ILE E 5 33  ? 130.913 86.729  77.912  1.00 90.74  ?  33  ILE R O   1 
ATOM   6692 C CB  . ILE E 5 33  ? 131.767 89.296  76.640  1.00 90.74  ?  33  ILE R CB  1 
ATOM   6693 C CG1 . ILE E 5 33  ? 132.721 90.297  75.981  1.00 90.74  ?  33  ILE R CG1 1 
ATOM   6694 C CG2 . ILE E 5 33  ? 131.884 89.381  78.156  1.00 90.74  ?  33  ILE R CG2 1 
ATOM   6695 C CD1 . ILE E 5 33  ? 134.192 89.984  76.190  1.00 90.74  ?  33  ILE R CD1 1 
ATOM   6696 N N   . GLU E 5 34  ? 130.208 86.277  75.815  1.00 88.58  ?  34  GLU R N   1 
ATOM   6697 C CA  . GLU E 5 34  ? 129.188 85.342  76.277  1.00 88.58  ?  34  GLU R CA  1 
ATOM   6698 C C   . GLU E 5 34  ? 129.784 84.247  77.151  1.00 88.58  ?  34  GLU R C   1 
ATOM   6699 O O   . GLU E 5 34  ? 129.135 83.783  78.097  1.00 88.58  ?  34  GLU R O   1 
ATOM   6700 C CB  . GLU E 5 34  ? 128.463 84.734  75.073  1.00 88.58  ?  34  GLU R CB  1 
ATOM   6701 C CG  . GLU E 5 34  ? 127.481 83.623  75.416  1.00 88.58  ?  34  GLU R CG  1 
ATOM   6702 C CD  . GLU E 5 34  ? 128.089 82.238  75.288  1.00 88.58  ?  34  GLU R CD  1 
ATOM   6703 O OE1 . GLU E 5 34  ? 129.333 82.127  75.264  1.00 88.58  ?  34  GLU R OE1 1 
ATOM   6704 O OE2 . GLU E 5 34  ? 127.320 81.258  75.204  1.00 88.58  ?  34  GLU R OE2 1 
ATOM   6705 N N   . ASN E 5 35  ? 131.013 83.819  76.852  1.00 92.34  ?  35  ASN R N   1 
ATOM   6706 C CA  . ASN E 5 35  ? 131.667 82.817  77.687  1.00 92.34  ?  35  ASN R CA  1 
ATOM   6707 C C   . ASN E 5 35  ? 131.809 83.306  79.122  1.00 92.34  ?  35  ASN R C   1 
ATOM   6708 O O   . ASN E 5 35  ? 131.644 82.528  80.069  1.00 92.34  ?  35  ASN R O   1 
ATOM   6709 C CB  . ASN E 5 35  ? 133.034 82.461  77.103  1.00 92.34  ?  35  ASN R CB  1 
ATOM   6710 C CG  . ASN E 5 35  ? 132.939 81.903  75.697  1.00 92.34  ?  35  ASN R CG  1 
ATOM   6711 O OD1 . ASN E 5 35  ? 132.795 80.696  75.504  1.00 92.34  ?  35  ASN R OD1 1 
ATOM   6712 N ND2 . ASN E 5 35  ? 133.021 82.782  74.705  1.00 92.34  ?  35  ASN R ND2 1 
ATOM   6713 N N   . PHE E 5 36  ? 132.114 84.592  79.305  1.00 94.84  ?  36  PHE R N   1 
ATOM   6714 C CA  . PHE E 5 36  ? 132.207 85.152  80.648  1.00 94.84  ?  36  PHE R CA  1 
ATOM   6715 C C   . PHE E 5 36  ? 130.834 85.395  81.258  1.00 94.84  ?  36  PHE R C   1 
ATOM   6716 O O   . PHE E 5 36  ? 130.669 85.249  82.474  1.00 94.84  ?  36  PHE R O   1 
ATOM   6717 C CB  . PHE E 5 36  ? 133.003 86.458  80.621  1.00 94.84  ?  36  PHE R CB  1 
ATOM   6718 C CG  . PHE E 5 36  ? 133.025 87.181  81.940  1.00 94.84  ?  36  PHE R CG  1 
ATOM   6719 C CD1 . PHE E 5 36  ? 133.944 86.839  82.917  1.00 94.84  ?  36  PHE R CD1 1 
ATOM   6720 C CD2 . PHE E 5 36  ? 132.127 88.203  82.200  1.00 94.84  ?  36  PHE R CD2 1 
ATOM   6721 C CE1 . PHE E 5 36  ? 133.966 87.501  84.131  1.00 94.84  ?  36  PHE R CE1 1 
ATOM   6722 C CE2 . PHE E 5 36  ? 132.144 88.868  83.411  1.00 94.84  ?  36  PHE R CE2 1 
ATOM   6723 C CZ  . PHE E 5 36  ? 133.065 88.517  84.377  1.00 94.84  ?  36  PHE R CZ  1 
ATOM   6724 N N   . LYS E 5 37  ? 129.848 85.773  80.441  1.00 94.88  ?  37  LYS R N   1 
ATOM   6725 C CA  . LYS E 5 37  ? 128.505 86.004  80.961  1.00 94.88  ?  37  LYS R CA  1 
ATOM   6726 C C   . LYS E 5 37  ? 127.909 84.722  81.529  1.00 94.88  ?  37  LYS R C   1 
ATOM   6727 O O   . LYS E 5 37  ? 127.342 84.725  82.630  1.00 94.88  ?  37  LYS R O   1 
ATOM   6728 C CB  . LYS E 5 37  ? 127.609 86.568  79.857  1.00 94.88  ?  37  LYS R CB  1 
ATOM   6729 C CG  . LYS E 5 37  ? 128.067 87.914  79.315  1.00 94.88  ?  37  LYS R CG  1 
ATOM   6730 C CD  . LYS E 5 37  ? 127.287 88.322  78.071  1.00 94.88  ?  37  LYS R CD  1 
ATOM   6731 C CE  . LYS E 5 37  ? 125.813 88.541  78.368  1.00 94.88  ?  37  LYS R CE  1 
ATOM   6732 N NZ  . LYS E 5 37  ? 125.059 88.993  77.166  1.00 94.88  1  37  LYS R NZ  1 
ATOM   6733 N N   . ARG E 5 38  ? 128.027 83.615  80.791  1.00 95.08  ?  38  ARG R N   1 
ATOM   6734 C CA  . ARG E 5 38  ? 127.475 82.346  81.251  1.00 95.08  ?  38  ARG R CA  1 
ATOM   6735 C C   . ARG E 5 38  ? 128.011 81.938  82.616  1.00 95.08  ?  38  ARG R C   1 
ATOM   6736 O O   . ARG E 5 38  ? 127.311 81.240  83.357  1.00 95.08  ?  38  ARG R O   1 
ATOM   6737 C CB  . ARG E 5 38  ? 127.775 81.240  80.238  1.00 95.08  ?  38  ARG R CB  1 
ATOM   6738 C CG  . ARG E 5 38  ? 126.993 81.350  78.942  1.00 95.08  ?  38  ARG R CG  1 
ATOM   6739 C CD  . ARG E 5 38  ? 127.210 80.131  78.056  1.00 95.08  ?  38  ARG R CD  1 
ATOM   6740 N NE  . ARG E 5 38  ? 128.600 79.998  77.623  1.00 95.08  ?  38  ARG R NE  1 
ATOM   6741 C CZ  . ARG E 5 38  ? 129.535 79.306  78.270  1.00 95.08  ?  38  ARG R CZ  1 
ATOM   6742 N NH1 . ARG E 5 38  ? 129.247 78.669  79.399  1.00 95.08  1  38  ARG R NH1 1 
ATOM   6743 N NH2 . ARG E 5 38  ? 130.768 79.251  77.786  1.00 95.08  ?  38  ARG R NH2 1 
ATOM   6744 N N   . GLU E 5 39  ? 129.231 82.347  82.961  1.00 95.64  ?  39  GLU R N   1 
ATOM   6745 C CA  . GLU E 5 39  ? 129.819 81.995  84.247  1.00 95.64  ?  39  GLU R CA  1 
ATOM   6746 C C   . GLU E 5 39  ? 129.600 83.066  85.305  1.00 95.64  ?  39  GLU R C   1 
ATOM   6747 O O   . GLU E 5 39  ? 129.623 82.757  86.502  1.00 95.64  ?  39  GLU R O   1 
ATOM   6748 C CB  . GLU E 5 39  ? 131.321 81.740  84.083  1.00 95.64  ?  39  GLU R CB  1 
ATOM   6749 C CG  . GLU E 5 39  ? 132.027 81.308  85.360  1.00 95.64  ?  39  GLU R CG  1 
ATOM   6750 C CD  . GLU E 5 39  ? 133.495 81.004  85.139  1.00 95.64  ?  39  GLU R CD  1 
ATOM   6751 O OE1 . GLU E 5 39  ? 133.962 81.126  83.987  1.00 95.64  ?  39  GLU R OE1 1 
ATOM   6752 O OE2 . GLU E 5 39  ? 134.183 80.644  86.117  1.00 95.64  ?  39  GLU R OE2 1 
ATOM   6753 N N   . PHE E 5 40  ? 129.388 84.317  84.893  1.00 97.54  ?  40  PHE R N   1 
ATOM   6754 C CA  . PHE E 5 40  ? 129.251 85.403  85.857  1.00 97.54  ?  40  PHE R CA  1 
ATOM   6755 C C   . PHE E 5 40  ? 127.807 85.559  86.323  1.00 97.54  ?  40  PHE R C   1 
ATOM   6756 O O   . PHE E 5 40  ? 127.547 85.677  87.525  1.00 97.54  ?  40  PHE R O   1 
ATOM   6757 C CB  . PHE E 5 40  ? 129.763 86.707  85.241  1.00 97.54  ?  40  PHE R CB  1 
ATOM   6758 C CG  . PHE E 5 40  ? 129.884 87.835  86.223  1.00 97.54  ?  40  PHE R CG  1 
ATOM   6759 C CD1 . PHE E 5 40  ? 130.923 87.864  87.138  1.00 97.54  ?  40  PHE R CD1 1 
ATOM   6760 C CD2 . PHE E 5 40  ? 128.966 88.871  86.226  1.00 97.54  ?  40  PHE R CD2 1 
ATOM   6761 C CE1 . PHE E 5 40  ? 131.040 88.902  88.042  1.00 97.54  ?  40  PHE R CE1 1 
ATOM   6762 C CE2 . PHE E 5 40  ? 129.079 89.911  87.126  1.00 97.54  ?  40  PHE R CE2 1 
ATOM   6763 C CZ  . PHE E 5 40  ? 130.117 89.927  88.035  1.00 97.54  ?  40  PHE R CZ  1 
ATOM   6764 N N   . PHE E 5 41  ? 126.855 85.559  85.388  1.00 97.53  ?  41  PHE R N   1 
ATOM   6765 C CA  . PHE E 5 41  ? 125.460 85.791  85.760  1.00 97.53  ?  41  PHE R CA  1 
ATOM   6766 C C   . PHE E 5 41  ? 124.937 84.776  86.766  1.00 97.53  ?  41  PHE R C   1 
ATOM   6767 O O   . PHE E 5 41  ? 124.360 85.193  87.786  1.00 97.53  ?  41  PHE R O   1 
ATOM   6768 C CB  . PHE E 5 41  ? 124.586 85.803  84.499  1.00 97.53  ?  41  PHE R CB  1 
ATOM   6769 C CG  . PHE E 5 41  ? 124.682 87.072  83.690  1.00 97.53  ?  41  PHE R CG  1 
ATOM   6770 C CD1 . PHE E 5 41  ? 124.779 88.310  84.306  1.00 97.53  ?  41  PHE R CD1 1 
ATOM   6771 C CD2 . PHE E 5 41  ? 124.664 87.021  82.307  1.00 97.53  ?  41  PHE R CD2 1 
ATOM   6772 C CE1 . PHE E 5 41  ? 124.860 89.468  83.559  1.00 97.53  ?  41  PHE R CE1 1 
ATOM   6773 C CE2 . PHE E 5 41  ? 124.745 88.177  81.556  1.00 97.53  ?  41  PHE R CE2 1 
ATOM   6774 C CZ  . PHE E 5 41  ? 124.844 89.400  82.182  1.00 97.53  ?  41  PHE R CZ  1 
ATOM   6775 N N   . PRO E 5 42  ? 125.087 83.464  86.561  1.00 98.19  ?  42  PRO R N   1 
ATOM   6776 C CA  . PRO E 5 42  ? 124.415 82.507  87.458  1.00 98.19  ?  42  PRO R CA  1 
ATOM   6777 C C   . PRO E 5 42  ? 124.727 82.712  88.930  1.00 98.19  ?  42  PRO R C   1 
ATOM   6778 O O   . PRO E 5 42  ? 123.817 82.613  89.762  1.00 98.19  ?  42  PRO R O   1 
ATOM   6779 C CB  . PRO E 5 42  ? 124.926 81.146  86.963  1.00 98.19  ?  42  PRO R CB  1 
ATOM   6780 C CG  . PRO E 5 42  ? 125.327 81.377  85.553  1.00 98.19  ?  42  PRO R CG  1 
ATOM   6781 C CD  . PRO E 5 42  ? 125.845 82.782  85.498  1.00 98.19  ?  42  PRO R CD  1 
ATOM   6782 N N   . ILE E 5 43  ? 125.978 82.997  89.281  1.00 98.19  ?  43  ILE R N   1 
ATOM   6783 C CA  . ILE E 5 43  ? 126.351 83.126  90.687  1.00 98.19  ?  43  ILE R CA  1 
ATOM   6784 C C   . ILE E 5 43  ? 126.011 84.510  91.228  1.00 98.19  ?  43  ILE R C   1 
ATOM   6785 O O   . ILE E 5 43  ? 125.461 84.633  92.326  1.00 98.19  ?  43  ILE R O   1 
ATOM   6786 C CB  . ILE E 5 43  ? 127.850 82.801  90.865  1.00 98.19  ?  43  ILE R CB  1 
ATOM   6787 C CG1 . ILE E 5 43  ? 128.223 82.760  92.351  1.00 98.19  ?  43  ILE R CG1 1 
ATOM   6788 C CG2 . ILE E 5 43  ? 128.723 83.822  90.144  1.00 98.19  ?  43  ILE R CG2 1 
ATOM   6789 C CD1 . ILE E 5 43  ? 127.519 81.673  93.136  1.00 98.19  ?  43  ILE R CD1 1 
ATOM   6790 N N   . VAL E 5 44  ? 126.323 85.565  90.473  1.00 98.13  ?  44  VAL R N   1 
ATOM   6791 C CA  . VAL E 5 44  ? 126.097 86.919  90.968  1.00 98.13  ?  44  VAL R CA  1 
ATOM   6792 C C   . VAL E 5 44  ? 124.605 87.182  91.135  1.00 98.13  ?  44  VAL R C   1 
ATOM   6793 O O   . VAL E 5 44  ? 124.159 87.672  92.179  1.00 98.13  ?  44  VAL R O   1 
ATOM   6794 C CB  . VAL E 5 44  ? 126.759 87.953  90.036  1.00 98.13  ?  44  VAL R CB  1 
ATOM   6795 C CG1 . VAL E 5 44  ? 126.077 87.983  88.675  1.00 98.13  ?  44  VAL R CG1 1 
ATOM   6796 C CG2 . VAL E 5 44  ? 126.740 89.333  90.678  1.00 98.13  ?  44  VAL R CG2 1 
ATOM   6797 N N   . TYR E 5 45  ? 123.807 86.850  90.116  1.00 98.16  ?  45  TYR R N   1 
ATOM   6798 C CA  . TYR E 5 45  ? 122.369 87.066  90.220  1.00 98.16  ?  45  TYR R CA  1 
ATOM   6799 C C   . TYR E 5 45  ? 121.761 86.184  91.301  1.00 98.16  ?  45  TYR R C   1 
ATOM   6800 O O   . TYR E 5 45  ? 120.838 86.605  92.006  1.00 98.16  ?  45  TYR R O   1 
ATOM   6801 C CB  . TYR E 5 45  ? 121.695 86.805  88.871  1.00 98.16  ?  45  TYR R CB  1 
ATOM   6802 C CG  . TYR E 5 45  ? 121.928 87.876  87.821  1.00 98.16  ?  45  TYR R CG  1 
ATOM   6803 C CD1 . TYR E 5 45  ? 122.581 89.065  88.131  1.00 98.16  ?  45  TYR R CD1 1 
ATOM   6804 C CD2 . TYR E 5 45  ? 121.481 87.699  86.518  1.00 98.16  ?  45  TYR R CD2 1 
ATOM   6805 C CE1 . TYR E 5 45  ? 122.787 90.039  87.173  1.00 98.16  ?  45  TYR R CE1 1 
ATOM   6806 C CE2 . TYR E 5 45  ? 121.682 88.669  85.554  1.00 98.16  ?  45  TYR R CE2 1 
ATOM   6807 C CZ  . TYR E 5 45  ? 122.335 89.836  85.887  1.00 98.16  ?  45  TYR R CZ  1 
ATOM   6808 O OH  . TYR E 5 45  ? 122.539 90.804  84.931  1.00 98.16  ?  45  TYR R OH  1 
ATOM   6809 N N   . LEU E 5 46  ? 122.277 84.965  91.464  1.00 98.24  ?  46  LEU R N   1 
ATOM   6810 C CA  . LEU E 5 46  ? 121.751 84.076  92.495  1.00 98.24  ?  46  LEU R CA  1 
ATOM   6811 C C   . LEU E 5 46  ? 121.994 84.648  93.887  1.00 98.24  ?  46  LEU R C   1 
ATOM   6812 O O   . LEU E 5 46  ? 121.078 84.700  94.718  1.00 98.24  ?  46  LEU R O   1 
ATOM   6813 C CB  . LEU E 5 46  ? 122.383 82.690  92.362  1.00 98.24  ?  46  LEU R CB  1 
ATOM   6814 C CG  . LEU E 5 46  ? 121.964 81.651  93.405  1.00 98.24  ?  46  LEU R CG  1 
ATOM   6815 C CD1 . LEU E 5 46  ? 120.459 81.426  93.374  1.00 98.24  ?  46  LEU R CD1 1 
ATOM   6816 C CD2 . LEU E 5 46  ? 122.706 80.343  93.180  1.00 98.24  ?  46  LEU R CD2 1 
ATOM   6817 N N   . ILE E 5 47  ? 123.225 85.084  94.163  1.00 98.01  ?  47  ILE R N   1 
ATOM   6818 C CA  . ILE E 5 47  ? 123.532 85.621  95.486  1.00 98.01  ?  47  ILE R CA  1 
ATOM   6819 C C   . ILE E 5 47  ? 122.784 86.930  95.715  1.00 98.01  ?  47  ILE R C   1 
ATOM   6820 O O   . ILE E 5 47  ? 122.323 87.213  96.831  1.00 98.01  ?  47  ILE R O   1 
ATOM   6821 C CB  . ILE E 5 47  ? 125.055 85.790  95.655  1.00 98.01  ?  47  ILE R CB  1 
ATOM   6822 C CG1 . ILE E 5 47  ? 125.402 86.204  97.087  1.00 98.01  ?  47  ILE R CG1 1 
ATOM   6823 C CG2 . ILE E 5 47  ? 125.604 86.816  94.676  1.00 98.01  ?  47  ILE R CG2 1 
ATOM   6824 C CD1 . ILE E 5 47  ? 124.976 85.203  98.142  1.00 98.01  ?  47  ILE R CD1 1 
ATOM   6825 N N   . ILE E 5 48  ? 122.639 87.746  94.666  1.00 98.34  ?  48  ILE R N   1 
ATOM   6826 C CA  . ILE E 5 48  ? 121.887 88.990  94.800  1.00 98.34  ?  48  ILE R CA  1 
ATOM   6827 C C   . ILE E 5 48  ? 120.434 88.693  95.139  1.00 98.34  ?  48  ILE R C   1 
ATOM   6828 O O   . ILE E 5 48  ? 119.848 89.328  96.020  1.00 98.34  ?  48  ILE R O   1 
ATOM   6829 C CB  . ILE E 5 48  ? 122.012 89.833  93.517  1.00 98.34  ?  48  ILE R CB  1 
ATOM   6830 C CG1 . ILE E 5 48  ? 123.434 90.388  93.390  1.00 98.34  ?  48  ILE R CG1 1 
ATOM   6831 C CG2 . ILE E 5 48  ? 120.991 90.967  93.524  1.00 98.34  ?  48  ILE R CG2 1 
ATOM   6832 C CD1 . ILE E 5 48  ? 123.735 91.019  92.046  1.00 98.34  ?  48  ILE R CD1 1 
ATOM   6833 N N   . PHE E 5 49  ? 119.826 87.730  94.443  1.00 98.51  ?  49  PHE R N   1 
ATOM   6834 C CA  . PHE E 5 49  ? 118.454 87.342  94.752  1.00 98.51  ?  49  PHE R CA  1 
ATOM   6835 C C   . PHE E 5 49  ? 118.340 86.849  96.188  1.00 98.51  ?  49  PHE R C   1 
ATOM   6836 O O   . PHE E 5 49  ? 117.412 87.224  96.915  1.00 98.51  ?  49  PHE R O   1 
ATOM   6837 C CB  . PHE E 5 49  ? 117.986 86.266  93.771  1.00 98.51  ?  49  PHE R CB  1 
ATOM   6838 C CG  . PHE E 5 49  ? 116.767 85.514  94.227  1.00 98.51  ?  49  PHE R CG  1 
ATOM   6839 C CD1 . PHE E 5 49  ? 115.498 86.025  94.010  1.00 98.51  ?  49  PHE R CD1 1 
ATOM   6840 C CD2 . PHE E 5 49  ? 116.890 84.291  94.866  1.00 98.51  ?  49  PHE R CD2 1 
ATOM   6841 C CE1 . PHE E 5 49  ? 114.376 85.333  94.426  1.00 98.51  ?  49  PHE R CE1 1 
ATOM   6842 C CE2 . PHE E 5 49  ? 115.771 83.595  95.285  1.00 98.51  ?  49  PHE R CE2 1 
ATOM   6843 C CZ  . PHE E 5 49  ? 114.513 84.117  95.064  1.00 98.51  ?  49  PHE R CZ  1 
ATOM   6844 N N   . PHE E 5 50  ? 119.278 86.001  96.613  1.00 97.71  ?  50  PHE R N   1 
ATOM   6845 C CA  . PHE E 5 50  ? 119.238 85.474  97.973  1.00 97.71  ?  50  PHE R CA  1 
ATOM   6846 C C   . PHE E 5 50  ? 119.244 86.602  98.997  1.00 97.71  ?  50  PHE R C   1 
ATOM   6847 O O   . PHE E 5 50  ? 118.363 86.677  99.864  1.00 97.71  ?  50  PHE R O   1 
ATOM   6848 C CB  . PHE E 5 50  ? 120.420 84.531  98.201  1.00 97.71  ?  50  PHE R CB  1 
ATOM   6849 C CG  . PHE E 5 50  ? 120.479 83.956  99.588  1.00 97.71  ?  50  PHE R CG  1 
ATOM   6850 C CD1 . PHE E 5 50  ? 119.763 82.816  99.911  1.00 97.71  ?  50  PHE R CD1 1 
ATOM   6851 C CD2 . PHE E 5 50  ? 121.254 84.555  100.568 1.00 97.71  ?  50  PHE R CD2 1 
ATOM   6852 C CE1 . PHE E 5 50  ? 119.816 82.285  101.185 1.00 97.71  ?  50  PHE R CE1 1 
ATOM   6853 C CE2 . PHE E 5 50  ? 121.311 84.028  101.844 1.00 97.71  ?  50  PHE R CE2 1 
ATOM   6854 C CZ  . PHE E 5 50  ? 120.591 82.892  102.153 1.00 97.71  ?  50  PHE R CZ  1 
ATOM   6855 N N   . TRP E 5 51  ? 120.238 87.491  98.915  1.00 97.46  ?  51  TRP R N   1 
ATOM   6856 C CA  . TRP E 5 51  ? 120.338 88.566  99.899  1.00 97.46  ?  51  TRP R CA  1 
ATOM   6857 C C   . TRP E 5 51  ? 119.148 89.514  99.809  1.00 97.46  ?  51  TRP R C   1 
ATOM   6858 O O   . TRP E 5 51  ? 118.614 89.952  100.837 1.00 97.46  ?  51  TRP R O   1 
ATOM   6859 C CB  . TRP E 5 51  ? 121.647 89.334  99.715  1.00 97.46  ?  51  TRP R CB  1 
ATOM   6860 C CG  . TRP E 5 51  ? 122.837 88.636  100.298 1.00 97.46  ?  51  TRP R CG  1 
ATOM   6861 C CD1 . TRP E 5 51  ? 123.870 88.070  99.614  1.00 97.46  ?  51  TRP R CD1 1 
ATOM   6862 C CD2 . TRP E 5 51  ? 123.113 88.425  101.688 1.00 97.46  ?  51  TRP R CD2 1 
ATOM   6863 N NE1 . TRP E 5 51  ? 124.776 87.522  100.489 1.00 97.46  ?  51  TRP R NE1 1 
ATOM   6864 C CE2 . TRP E 5 51  ? 124.334 87.726  101.770 1.00 97.46  ?  51  TRP R CE2 1 
ATOM   6865 C CE3 . TRP E 5 51  ? 122.448 88.761  102.872 1.00 97.46  ?  51  TRP R CE3 1 
ATOM   6866 C CZ2 . TRP E 5 51  ? 124.903 87.357  102.987 1.00 97.46  ?  51  TRP R CZ2 1 
ATOM   6867 C CZ3 . TRP E 5 51  ? 123.015 88.393  104.079 1.00 97.46  ?  51  TRP R CZ3 1 
ATOM   6868 C CH2 . TRP E 5 51  ? 124.230 87.698  104.127 1.00 97.46  ?  51  TRP R CH2 1 
ATOM   6869 N N   . GLY E 5 52  ? 118.716 89.844  98.590  1.00 98.08  ?  52  GLY R N   1 
ATOM   6870 C CA  . GLY E 5 52  ? 117.601 90.758  98.436  1.00 98.08  ?  52  GLY R CA  1 
ATOM   6871 C C   . GLY E 5 52  ? 116.321 90.216  99.036  1.00 98.08  ?  52  GLY R C   1 
ATOM   6872 O O   . GLY E 5 52  ? 115.569 90.950  99.675  1.00 98.08  ?  52  GLY R O   1 
ATOM   6873 N N   . VAL E 5 53  ? 116.052 88.924  98.838  1.00 97.99  ?  53  VAL R N   1 
ATOM   6874 C CA  . VAL E 5 53  ? 114.886 88.313  99.468  1.00 97.99  ?  53  VAL R CA  1 
ATOM   6875 C C   . VAL E 5 53  ? 115.046 88.323  100.982 1.00 97.99  ?  53  VAL R C   1 
ATOM   6876 O O   . VAL E 5 53  ? 114.170 88.802  101.716 1.00 97.99  ?  53  VAL R O   1 
ATOM   6877 C CB  . VAL E 5 53  ? 114.670 86.886  98.932  1.00 97.99  ?  53  VAL R CB  1 
ATOM   6878 C CG1 . VAL E 5 53  ? 113.597 86.170  99.740  1.00 97.99  ?  53  VAL R CG1 1 
ATOM   6879 C CG2 . VAL E 5 53  ? 114.291 86.926  97.461  1.00 97.99  ?  53  VAL R CG2 1 
ATOM   6880 N N   . LEU E 5 54  ? 116.176 87.802  101.474 1.00 97.09  ?  54  LEU R N   1 
ATOM   6881 C CA  . LEU E 5 54  ? 116.405 87.750  102.914 1.00 97.09  ?  54  LEU R CA  1 
ATOM   6882 C C   . LEU E 5 54  ? 116.185 89.107  103.568 1.00 97.09  ?  54  LEU R C   1 
ATOM   6883 O O   . LEU E 5 54  ? 115.713 89.179  104.708 1.00 97.09  ?  54  LEU R O   1 
ATOM   6884 C CB  . LEU E 5 54  ? 117.823 87.250  103.199 1.00 97.09  ?  54  LEU R CB  1 
ATOM   6885 C CG  . LEU E 5 54  ? 118.229 87.158  104.673 1.00 97.09  ?  54  LEU R CG  1 
ATOM   6886 C CD1 . LEU E 5 54  ? 117.305 86.219  105.434 1.00 97.09  ?  54  LEU R CD1 1 
ATOM   6887 C CD2 . LEU E 5 54  ? 119.675 86.706  104.798 1.00 97.09  ?  54  LEU R CD2 1 
ATOM   6888 N N   . GLY E 5 55  ? 116.518 90.189  102.869 1.00 97.35  ?  55  GLY R N   1 
ATOM   6889 C CA  . GLY E 5 55  ? 116.321 91.517  103.414 1.00 97.35  ?  55  GLY R CA  1 
ATOM   6890 C C   . GLY E 5 55  ? 114.902 92.030  103.270 1.00 97.35  ?  55  GLY R C   1 
ATOM   6891 O O   . GLY E 5 55  ? 114.280 92.441  104.256 1.00 97.35  ?  55  GLY R O   1 
ATOM   6892 N N   . ASN E 5 56  ? 114.376 91.999  102.043 1.00 98.12  ?  56  ASN R N   1 
ATOM   6893 C CA  . ASN E 5 56  ? 113.095 92.632  101.755 1.00 98.12  ?  56  ASN R CA  1 
ATOM   6894 C C   . ASN E 5 56  ? 111.934 91.911  102.422 1.00 98.12  ?  56  ASN R C   1 
ATOM   6895 O O   . ASN E 5 56  ? 110.951 92.556  102.797 1.00 98.12  ?  56  ASN R O   1 
ATOM   6896 C CB  . ASN E 5 56  ? 112.875 92.695  100.244 1.00 98.12  ?  56  ASN R CB  1 
ATOM   6897 C CG  . ASN E 5 56  ? 113.974 93.451  99.527  1.00 98.12  ?  56  ASN R CG  1 
ATOM   6898 O OD1 . ASN E 5 56  ? 115.068 93.634  100.061 1.00 98.12  ?  56  ASN R OD1 1 
ATOM   6899 N ND2 . ASN E 5 56  ? 113.690 93.894  98.309  1.00 98.12  ?  56  ASN R ND2 1 
ATOM   6900 N N   . GLY E 5 57  ? 112.007 90.589  102.569 1.00 97.67  ?  57  GLY R N   1 
ATOM   6901 C CA  . GLY E 5 57  ? 110.951 89.884  103.267 1.00 97.67  ?  57  GLY R CA  1 
ATOM   6902 C C   . GLY E 5 57  ? 110.727 90.463  104.648 1.00 97.67  ?  57  GLY R C   1 
ATOM   6903 O O   . GLY E 5 57  ? 109.615 90.882  104.991 1.00 97.67  ?  57  GLY R O   1 
ATOM   6904 N N   . LEU E 5 58  ? 111.798 90.512  105.444 1.00 96.82  ?  58  LEU R N   1 
ATOM   6905 C CA  . LEU E 5 58  ? 111.695 91.056  106.792 1.00 96.82  ?  58  LEU R CA  1 
ATOM   6906 C C   . LEU E 5 58  ? 111.404 92.551  106.774 1.00 96.82  ?  58  LEU R C   1 
ATOM   6907 O O   . LEU E 5 58  ? 110.673 93.047  107.638 1.00 96.82  ?  58  LEU R O   1 
ATOM   6908 C CB  . LEU E 5 58  ? 112.982 90.770  107.566 1.00 96.82  ?  58  LEU R CB  1 
ATOM   6909 C CG  . LEU E 5 58  ? 112.984 91.125  109.055 1.00 96.82  ?  58  LEU R CG  1 
ATOM   6910 C CD1 . LEU E 5 58  ? 111.861 90.408  109.790 1.00 96.82  ?  58  LEU R CD1 1 
ATOM   6911 C CD2 . LEU E 5 58  ? 114.333 90.785  109.670 1.00 96.82  ?  58  LEU R CD2 1 
ATOM   6912 N N   . SER E 5 59  ? 111.953 93.283  105.802 1.00 97.48  ?  59  SER R N   1 
ATOM   6913 C CA  . SER E 5 59  ? 111.677 94.714  105.714 1.00 97.48  ?  59  SER R CA  1 
ATOM   6914 C C   . SER E 5 59  ? 110.183 94.971  105.552 1.00 97.48  ?  59  SER R C   1 
ATOM   6915 O O   . SER E 5 59  ? 109.609 95.829  106.233 1.00 97.48  ?  59  SER R O   1 
ATOM   6916 C CB  . SER E 5 59  ? 112.459 95.324  104.550 1.00 97.48  ?  59  SER R CB  1 
ATOM   6917 O OG  . SER E 5 59  ? 112.259 96.724  104.478 1.00 97.48  ?  59  SER R OG  1 
ATOM   6918 N N   . ILE E 5 60  ? 109.535 94.227  104.654 1.00 97.34  ?  60  ILE R N   1 
ATOM   6919 C CA  . ILE E 5 60  ? 108.106 94.409  104.427 1.00 97.34  ?  60  ILE R CA  1 
ATOM   6920 C C   . ILE E 5 60  ? 107.307 93.892  105.616 1.00 97.34  ?  60  ILE R C   1 
ATOM   6921 O O   . ILE E 5 60  ? 106.301 94.493  106.012 1.00 97.34  ?  60  ILE R O   1 
ATOM   6922 C CB  . ILE E 5 60  ? 107.683 93.721  103.116 1.00 97.34  ?  60  ILE R CB  1 
ATOM   6923 C CG1 . ILE E 5 60  ? 108.419 94.351  101.929 1.00 97.34  ?  60  ILE R CG1 1 
ATOM   6924 C CG2 . ILE E 5 60  ? 106.172 93.819  102.926 1.00 97.34  ?  60  ILE R CG2 1 
ATOM   6925 C CD1 . ILE E 5 60  ? 108.202 93.633  100.614 1.00 97.34  ?  60  ILE R CD1 1 
ATOM   6926 N N   . TYR E 5 61  ? 107.735 92.771  106.206 1.00 96.46  ?  61  TYR R N   1 
ATOM   6927 C CA  . TYR E 5 61  ? 107.051 92.269  107.393 1.00 96.46  ?  61  TYR R CA  1 
ATOM   6928 C C   . TYR E 5 61  ? 107.079 93.290  108.522 1.00 96.46  ?  61  TYR R C   1 
ATOM   6929 O O   . TYR E 5 61  ? 106.136 93.361  109.319 1.00 96.46  ?  61  TYR R O   1 
ATOM   6930 C CB  . TYR E 5 61  ? 107.686 90.955  107.848 1.00 96.46  ?  61  TYR R CB  1 
ATOM   6931 C CG  . TYR E 5 61  ? 107.083 90.393  109.115 1.00 96.46  ?  61  TYR R CG  1 
ATOM   6932 C CD1 . TYR E 5 61  ? 105.916 89.642  109.078 1.00 96.46  ?  61  TYR R CD1 1 
ATOM   6933 C CD2 . TYR E 5 61  ? 107.683 90.610  110.349 1.00 96.46  ?  61  TYR R CD2 1 
ATOM   6934 C CE1 . TYR E 5 61  ? 105.361 89.126  110.234 1.00 96.46  ?  61  TYR R CE1 1 
ATOM   6935 C CE2 . TYR E 5 61  ? 107.136 90.097  111.510 1.00 96.46  ?  61  TYR R CE2 1 
ATOM   6936 C CZ  . TYR E 5 61  ? 105.976 89.356  111.447 1.00 96.46  ?  61  TYR R CZ  1 
ATOM   6937 O OH  . TYR E 5 61  ? 105.428 88.844  112.600 1.00 96.46  ?  61  TYR R OH  1 
ATOM   6938 N N   . VAL E 5 62  ? 108.146 94.084  108.607 1.00 95.94  ?  62  VAL R N   1 
ATOM   6939 C CA  . VAL E 5 62  ? 108.246 95.092  109.657 1.00 95.94  ?  62  VAL R CA  1 
ATOM   6940 C C   . VAL E 5 62  ? 107.465 96.347  109.283 1.00 95.94  ?  62  VAL R C   1 
ATOM   6941 O O   . VAL E 5 62  ? 106.827 96.969  110.139 1.00 95.94  ?  62  VAL R O   1 
ATOM   6942 C CB  . VAL E 5 62  ? 109.725 95.405  109.943 1.00 95.94  ?  62  VAL R CB  1 
ATOM   6943 C CG1 . VAL E 5 62  ? 109.848 96.590  110.884 1.00 95.94  ?  62  VAL R CG1 1 
ATOM   6944 C CG2 . VAL E 5 62  ? 110.421 94.187  110.530 1.00 95.94  ?  62  VAL R CG2 1 
ATOM   6945 N N   . PHE E 5 63  ? 107.500 96.742  108.007 1.00 94.69  ?  63  PHE R N   1 
ATOM   6946 C CA  . PHE E 5 63  ? 106.765 97.931  107.587 1.00 94.69  ?  63  PHE R CA  1 
ATOM   6947 C C   . PHE E 5 63  ? 105.262 97.752  107.754 1.00 94.69  ?  63  PHE R C   1 
ATOM   6948 O O   . PHE E 5 63  ? 104.582 98.664  108.239 1.00 94.69  ?  63  PHE R O   1 
ATOM   6949 C CB  . PHE E 5 63  ? 107.087 98.268  106.129 1.00 94.69  ?  63  PHE R CB  1 
ATOM   6950 C CG  . PHE E 5 63  ? 108.459 98.852  105.920 1.00 94.69  ?  63  PHE R CG  1 
ATOM   6951 C CD1 . PHE E 5 63  ? 108.999 99.753  106.824 1.00 94.69  ?  63  PHE R CD1 1 
ATOM   6952 C CD2 . PHE E 5 63  ? 109.206 98.502  104.808 1.00 94.69  ?  63  PHE R CD2 1 
ATOM   6953 C CE1 . PHE E 5 63  ? 110.256 100.288 106.626 1.00 94.69  ?  63  PHE R CE1 1 
ATOM   6954 C CE2 . PHE E 5 63  ? 110.464 99.035  104.604 1.00 94.69  ?  63  PHE R CE2 1 
ATOM   6955 C CZ  . PHE E 5 63  ? 110.990 99.928  105.515 1.00 94.69  ?  63  PHE R CZ  1 
ATOM   6956 N N   . LEU E 5 64  ? 104.726 96.595  107.365 1.00 93.65  ?  64  LEU R N   1 
ATOM   6957 C CA  . LEU E 5 64  ? 103.297 96.340  107.489 1.00 93.65  ?  64  LEU R CA  1 
ATOM   6958 C C   . LEU E 5 64  ? 102.836 96.239  108.937 1.00 93.65  ?  64  LEU R C   1 
ATOM   6959 O O   . LEU E 5 64  ? 101.626 96.185  109.180 1.00 93.65  ?  64  LEU R O   1 
ATOM   6960 C CB  . LEU E 5 64  ? 102.929 95.051  106.748 1.00 93.65  ?  64  LEU R CB  1 
ATOM   6961 C CG  . LEU E 5 64  ? 103.191 95.036  105.240 1.00 93.65  ?  64  LEU R CG  1 
ATOM   6962 C CD1 . LEU E 5 64  ? 102.885 93.662  104.662 1.00 93.65  ?  64  LEU R CD1 1 
ATOM   6963 C CD2 . LEU E 5 64  ? 102.371 96.107  104.537 1.00 93.65  ?  64  LEU R CD2 1 
ATOM   6964 N N   . GLN E 5 65  ? 103.758 96.212  109.892 1.00 91.63  ?  65  GLN R N   1 
ATOM   6965 C CA  . GLN E 5 65  ? 103.375 96.126  111.293 1.00 91.63  ?  65  GLN R CA  1 
ATOM   6966 C C   . GLN E 5 65  ? 102.665 97.412  111.714 1.00 91.63  ?  65  GLN R C   1 
ATOM   6967 O O   . GLN E 5 65  ? 103.155 98.510  111.412 1.00 91.63  ?  65  GLN R O   1 
ATOM   6968 C CB  . GLN E 5 65  ? 104.609 95.896  112.164 1.00 91.63  ?  65  GLN R CB  1 
ATOM   6969 C CG  . GLN E 5 65  ? 104.296 95.465  113.587 1.00 91.63  ?  65  GLN R CG  1 
ATOM   6970 C CD  . GLN E 5 65  ? 105.539 95.354  114.446 1.00 91.63  ?  65  GLN R CD  1 
ATOM   6971 O OE1 . GLN E 5 65  ? 106.598 95.876  114.096 1.00 91.63  ?  65  GLN R OE1 1 
ATOM   6972 N NE2 . GLN E 5 65  ? 105.418 94.670  115.577 1.00 91.63  ?  65  GLN R NE2 1 
ATOM   6973 N N   . PRO E 5 66  ? 101.516 97.329  112.406 1.00 87.66  ?  66  PRO R N   1 
ATOM   6974 C CA  . PRO E 5 66  ? 100.858 98.556  112.878 1.00 87.66  ?  66  PRO R CA  1 
ATOM   6975 C C   . PRO E 5 66  ? 101.400 99.034  114.216 1.00 87.66  ?  66  PRO R C   1 
ATOM   6976 O O   . PRO E 5 66  ? 100.756 99.831  114.905 1.00 87.66  ?  66  PRO R O   1 
ATOM   6977 C CB  . PRO E 5 66  ? 99.380  98.148  112.986 1.00 87.66  ?  66  PRO R CB  1 
ATOM   6978 C CG  . PRO E 5 66  ? 99.332  96.644  112.758 1.00 87.66  ?  66  PRO R CG  1 
ATOM   6979 C CD  . PRO E 5 66  ? 100.736 96.137  112.772 1.00 87.66  ?  66  PRO R CD  1 
ATOM   6980 N N   . TYR E 5 67  ? 102.585 98.550  114.593 1.00 88.37  ?  67  TYR R N   1 
ATOM   6981 C CA  . TYR E 5 67  ? 103.098 98.795  115.938 1.00 88.37  ?  67  TYR R CA  1 
ATOM   6982 C C   . TYR E 5 67  ? 103.230 100.287 116.225 1.00 88.37  ?  67  TYR R C   1 
ATOM   6983 O O   . TYR E 5 67  ? 102.616 100.804 117.165 1.00 88.37  ?  67  TYR R O   1 
ATOM   6984 C CB  . TYR E 5 67  ? 104.444 98.091  116.117 1.00 88.37  ?  67  TYR R CB  1 
ATOM   6985 C CG  . TYR E 5 67  ? 105.111 98.379  117.442 1.00 88.37  ?  67  TYR R CG  1 
ATOM   6986 C CD1 . TYR E 5 67  ? 104.714 97.723  118.600 1.00 88.37  ?  67  TYR R CD1 1 
ATOM   6987 C CD2 . TYR E 5 67  ? 106.141 99.304  117.534 1.00 88.37  ?  67  TYR R CD2 1 
ATOM   6988 C CE1 . TYR E 5 67  ? 105.323 97.984  119.813 1.00 88.37  ?  67  TYR R CE1 1 
ATOM   6989 C CE2 . TYR E 5 67  ? 106.756 99.571  118.742 1.00 88.37  ?  67  TYR R CE2 1 
ATOM   6990 C CZ  . TYR E 5 67  ? 106.344 98.908  119.878 1.00 88.37  ?  67  TYR R CZ  1 
ATOM   6991 O OH  . TYR E 5 67  ? 106.954 99.172  121.083 1.00 88.37  ?  67  TYR R OH  1 
ATOM   6992 N N   . LYS E 5 68  ? 104.027 100.999 115.427 1.00 84.15  ?  68  LYS R N   1 
ATOM   6993 C CA  . LYS E 5 68  ? 104.345 102.384 115.753 1.00 84.15  ?  68  LYS R CA  1 
ATOM   6994 C C   . LYS E 5 68  ? 103.364 103.370 115.129 1.00 84.15  ?  68  LYS R C   1 
ATOM   6995 O O   . LYS E 5 68  ? 102.652 104.076 115.850 1.00 84.15  ?  68  LYS R O   1 
ATOM   6996 C CB  . LYS E 5 68  ? 105.766 102.723 115.294 1.00 84.15  ?  68  LYS R CB  1 
ATOM   6997 C CG  . LYS E 5 68  ? 106.813 102.702 116.397 1.00 84.15  ?  68  LYS R CG  1 
ATOM   6998 C CD  . LYS E 5 68  ? 108.156 103.199 115.883 1.00 84.15  ?  68  LYS R CD  1 
ATOM   6999 C CE  . LYS E 5 68  ? 109.221 103.179 116.967 1.00 84.15  ?  68  LYS R CE  1 
ATOM   7000 N NZ  . LYS E 5 68  ? 109.499 101.799 117.451 1.00 84.15  1  68  LYS R NZ  1 
ATOM   7001 N N   . LYS E 5 69  ? 103.309 103.423 113.797 1.00 83.91  ?  69  LYS R N   1 
ATOM   7002 C CA  . LYS E 5 69  ? 102.471 104.405 113.116 1.00 83.91  ?  69  LYS R CA  1 
ATOM   7003 C C   . LYS E 5 69  ? 102.555 104.260 111.602 1.00 83.91  ?  69  LYS R C   1 
ATOM   7004 O O   . LYS E 5 69  ? 103.303 103.420 111.090 1.00 83.91  ?  69  LYS R O   1 
ATOM   7005 C CB  . LYS E 5 69  ? 102.879 105.823 113.527 1.00 83.91  ?  69  LYS R CB  1 
ATOM   7006 C CG  . LYS E 5 69  ? 102.708 106.117 115.013 1.00 83.91  ?  69  LYS R CG  1 
ATOM   7007 C CD  . LYS E 5 69  ? 101.239 106.152 115.419 1.00 83.91  ?  69  LYS R CD  1 
ATOM   7008 C CE  . LYS E 5 69  ? 101.064 106.446 116.904 1.00 83.91  ?  69  LYS R CE  1 
ATOM   7009 N NZ  . LYS E 5 69  ? 101.538 107.810 117.270 1.00 83.91  1  69  LYS R NZ  1 
ATOM   7010 N N   . SER E 5 70  ? 101.791 105.079 110.881 1.00 86.56  ?  70  SER R N   1 
ATOM   7011 C CA  . SER E 5 70  ? 101.846 105.154 109.426 1.00 86.56  ?  70  SER R CA  1 
ATOM   7012 C C   . SER E 5 70  ? 102.174 106.586 109.031 1.00 86.56  ?  70  SER R C   1 
ATOM   7013 O O   . SER E 5 70  ? 101.394 107.504 109.310 1.00 86.56  ?  70  SER R O   1 
ATOM   7014 C CB  . SER E 5 70  ? 100.521 104.712 108.800 1.00 86.56  ?  70  SER R CB  1 
ATOM   7015 O OG  . SER E 5 70  ? 100.205 103.378 109.155 1.00 86.56  ?  70  SER R OG  1 
ATOM   7016 N N   . THR E 5 71  ? 103.322 106.775 108.388 1.00 89.15  ?  71  THR R N   1 
ATOM   7017 C CA  . THR E 5 71  ? 103.802 108.087 107.980 1.00 89.15  ?  71  THR R CA  1 
ATOM   7018 C C   . THR E 5 71  ? 104.166 108.063 106.500 1.00 89.15  ?  71  THR R C   1 
ATOM   7019 O O   . THR E 5 71  ? 104.301 107.002 105.885 1.00 89.15  ?  71  THR R O   1 
ATOM   7020 C CB  . THR E 5 71  ? 105.015 108.510 108.822 1.00 89.15  ?  71  THR R CB  1 
ATOM   7021 O OG1 . THR E 5 71  ? 104.752 108.252 110.207 1.00 89.15  ?  71  THR R OG1 1 
ATOM   7022 C CG2 . THR E 5 71  ? 105.321 109.992 108.638 1.00 89.15  ?  71  THR R CG2 1 
ATOM   7023 N N   . SER E 5 72  ? 104.321 109.259 105.925 1.00 91.68  ?  72  SER R N   1 
ATOM   7024 C CA  . SER E 5 72  ? 104.692 109.360 104.517 1.00 91.68  ?  72  SER R CA  1 
ATOM   7025 C C   . SER E 5 72  ? 106.008 108.644 104.240 1.00 91.68  ?  72  SER R C   1 
ATOM   7026 O O   . SER E 5 72  ? 106.140 107.949 103.225 1.00 91.68  ?  72  SER R O   1 
ATOM   7027 C CB  . SER E 5 72  ? 104.788 110.828 104.104 1.00 91.68  ?  72  SER R CB  1 
ATOM   7028 O OG  . SER E 5 72  ? 105.729 111.521 104.906 1.00 91.68  ?  72  SER R OG  1 
ATOM   7029 N N   . VAL E 5 73  ? 106.996 108.810 105.122 1.00 92.64  ?  73  VAL R N   1 
ATOM   7030 C CA  . VAL E 5 73  ? 108.267 108.115 104.942 1.00 92.64  ?  73  VAL R CA  1 
ATOM   7031 C C   . VAL E 5 73  ? 108.053 106.608 104.974 1.00 92.64  ?  73  VAL R C   1 
ATOM   7032 O O   . VAL E 5 73  ? 108.694 105.858 104.228 1.00 92.64  ?  73  VAL R O   1 
ATOM   7033 C CB  . VAL E 5 73  ? 109.282 108.566 106.009 1.00 92.64  ?  73  VAL R CB  1 
ATOM   7034 C CG1 . VAL E 5 73  ? 108.806 108.182 107.405 1.00 92.64  ?  73  VAL R CG1 1 
ATOM   7035 C CG2 . VAL E 5 73  ? 110.653 107.971 105.722 1.00 92.64  ?  73  VAL R CG2 1 
ATOM   7036 N N   . ASN E 5 74  ? 107.143 106.141 105.833 1.00 93.79  ?  74  ASN R N   1 
ATOM   7037 C CA  . ASN E 5 74  ? 106.854 104.713 105.891 1.00 93.79  ?  74  ASN R CA  1 
ATOM   7038 C C   . ASN E 5 74  ? 106.250 104.222 104.582 1.00 93.79  ?  74  ASN R C   1 
ATOM   7039 O O   . ASN E 5 74  ? 106.621 103.155 104.084 1.00 93.79  ?  74  ASN R O   1 
ATOM   7040 C CB  . ASN E 5 74  ? 105.915 104.414 107.059 1.00 93.79  ?  74  ASN R CB  1 
ATOM   7041 C CG  . ASN E 5 74  ? 106.526 104.762 108.402 1.00 93.79  ?  74  ASN R CG  1 
ATOM   7042 O OD1 . ASN E 5 74  ? 105.984 105.573 109.152 1.00 93.79  ?  74  ASN R OD1 1 
ATOM   7043 N ND2 . ASN E 5 74  ? 107.661 104.147 108.711 1.00 93.79  ?  74  ASN R ND2 1 
ATOM   7044 N N   . VAL E 5 75  ? 105.324 104.992 104.006 1.00 95.64  ?  75  VAL R N   1 
ATOM   7045 C CA  . VAL E 5 75  ? 104.720 104.599 102.737 1.00 95.64  ?  75  VAL R CA  1 
ATOM   7046 C C   . VAL E 5 75  ? 105.767 104.583 101.630 1.00 95.64  ?  75  VAL R C   1 
ATOM   7047 O O   . VAL E 5 75  ? 105.791 103.674 100.790 1.00 95.64  ?  75  VAL R O   1 
ATOM   7048 C CB  . VAL E 5 75  ? 103.550 105.539 102.395 1.00 95.64  ?  75  VAL R CB  1 
ATOM   7049 C CG1 . VAL E 5 75  ? 102.968 105.195 101.031 1.00 95.64  ?  75  VAL R CG1 1 
ATOM   7050 C CG2 . VAL E 5 75  ? 102.476 105.466 103.471 1.00 95.64  ?  75  VAL R CG2 1 
ATOM   7051 N N   . PHE E 5 76  ? 106.642 105.590 101.605 1.00 96.16  ?  76  PHE R N   1 
ATOM   7052 C CA  . PHE E 5 76  ? 107.686 105.633 100.586 1.00 96.16  ?  76  PHE R CA  1 
ATOM   7053 C C   . PHE E 5 76  ? 108.627 104.442 100.712 1.00 96.16  ?  76  PHE R C   1 
ATOM   7054 O O   . PHE E 5 76  ? 108.975 103.810 99.707  1.00 96.16  ?  76  PHE R O   1 
ATOM   7055 C CB  . PHE E 5 76  ? 108.464 106.945 100.692 1.00 96.16  ?  76  PHE R CB  1 
ATOM   7056 C CG  . PHE E 5 76  ? 107.627 108.172 100.452 1.00 96.16  ?  76  PHE R CG  1 
ATOM   7057 C CD1 . PHE E 5 76  ? 106.616 108.170 99.505  1.00 96.16  ?  76  PHE R CD1 1 
ATOM   7058 C CD2 . PHE E 5 76  ? 107.853 109.329 101.179 1.00 96.16  ?  76  PHE R CD2 1 
ATOM   7059 C CE1 . PHE E 5 76  ? 105.850 109.299 99.286  1.00 96.16  ?  76  PHE R CE1 1 
ATOM   7060 C CE2 . PHE E 5 76  ? 107.089 110.460 100.965 1.00 96.16  ?  76  PHE R CE2 1 
ATOM   7061 C CZ  . PHE E 5 76  ? 106.086 110.444 100.018 1.00 96.16  ?  76  PHE R CZ  1 
ATOM   7062 N N   . MET E 5 77  ? 109.046 104.115 101.936 1.00 96.66  ?  77  MET R N   1 
ATOM   7063 C CA  . MET E 5 77  ? 109.929 102.971 102.127 1.00 96.66  ?  77  MET R CA  1 
ATOM   7064 C C   . MET E 5 77  ? 109.225 101.661 101.800 1.00 96.66  ?  77  MET R C   1 
ATOM   7065 O O   . MET E 5 77  ? 109.859 100.733 101.288 1.00 96.66  ?  77  MET R O   1 
ATOM   7066 C CB  . MET E 5 77  ? 110.458 102.950 103.561 1.00 96.66  ?  77  MET R CB  1 
ATOM   7067 C CG  . MET E 5 77  ? 111.416 104.087 103.874 1.00 96.66  ?  77  MET R CG  1 
ATOM   7068 S SD  . MET E 5 77  ? 112.113 103.987 105.533 1.00 96.66  ?  77  MET R SD  1 
ATOM   7069 C CE  . MET E 5 77  ? 113.296 105.331 105.477 1.00 96.66  ?  77  MET R CE  1 
ATOM   7070 N N   . LEU E 5 78  ? 107.921 101.568 102.068 1.00 97.39  ?  78  LEU R N   1 
ATOM   7071 C CA  . LEU E 5 78  ? 107.181 100.364 101.707 1.00 97.39  ?  78  LEU R CA  1 
ATOM   7072 C C   . LEU E 5 78  ? 107.108 100.202 100.194 1.00 97.39  ?  78  LEU R C   1 
ATOM   7073 O O   . LEU E 5 78  ? 107.291 99.095  99.674  1.00 97.39  ?  78  LEU R O   1 
ATOM   7074 C CB  . LEU E 5 78  ? 105.777 100.413 102.311 1.00 97.39  ?  78  LEU R CB  1 
ATOM   7075 C CG  . LEU E 5 78  ? 104.861 99.226  102.004 1.00 97.39  ?  78  LEU R CG  1 
ATOM   7076 C CD1 . LEU E 5 78  ? 105.466 97.928  102.516 1.00 97.39  ?  78  LEU R CD1 1 
ATOM   7077 C CD2 . LEU E 5 78  ? 103.482 99.450  102.604 1.00 97.39  ?  78  LEU R CD2 1 
ATOM   7078 N N   . ASN E 5 79  ? 106.842 101.292 99.472  1.00 98.27  ?  79  ASN R N   1 
ATOM   7079 C CA  . ASN E 5 79  ? 106.839 101.221 98.014  1.00 98.27  ?  79  ASN R CA  1 
ATOM   7080 C C   . ASN E 5 79  ? 108.219 100.857 97.481  1.00 98.27  ?  79  ASN R C   1 
ATOM   7081 O O   . ASN E 5 79  ? 108.339 100.069 96.535  1.00 98.27  ?  79  ASN R O   1 
ATOM   7082 C CB  . ASN E 5 79  ? 106.366 102.548 97.422  1.00 98.27  ?  79  ASN R CB  1 
ATOM   7083 C CG  . ASN E 5 79  ? 104.902 102.822 97.704  1.00 98.27  ?  79  ASN R CG  1 
ATOM   7084 O OD1 . ASN E 5 79  ? 104.020 102.321 97.007  1.00 98.27  ?  79  ASN R OD1 1 
ATOM   7085 N ND2 . ASN E 5 79  ? 104.637 103.625 98.727  1.00 98.27  ?  79  ASN R ND2 1 
ATOM   7086 N N   . LEU E 5 80  ? 109.273 101.421 98.076  1.00 98.24  ?  80  LEU R N   1 
ATOM   7087 C CA  . LEU E 5 80  ? 110.630 101.074 97.665  1.00 98.24  ?  80  LEU R CA  1 
ATOM   7088 C C   . LEU E 5 80  ? 110.906 99.591  97.881  1.00 98.24  ?  80  LEU R C   1 
ATOM   7089 O O   . LEU E 5 80  ? 111.475 98.922  97.009  1.00 98.24  ?  80  LEU R O   1 
ATOM   7090 C CB  . LEU E 5 80  ? 111.638 101.927 98.436  1.00 98.24  ?  80  LEU R CB  1 
ATOM   7091 C CG  . LEU E 5 80  ? 113.121 101.640 98.189  1.00 98.24  ?  80  LEU R CG  1 
ATOM   7092 C CD1 . LEU E 5 80  ? 113.473 101.850 96.727  1.00 98.24  ?  80  LEU R CD1 1 
ATOM   7093 C CD2 . LEU E 5 80  ? 113.987 102.515 99.081  1.00 98.24  ?  80  LEU R CD2 1 
ATOM   7094 N N   . ALA E 5 81  ? 110.511 99.060  99.040  1.00 98.36  ?  81  ALA R N   1 
ATOM   7095 C CA  . ALA E 5 81  ? 110.735 97.647  99.323  1.00 98.36  ?  81  ALA R CA  1 
ATOM   7096 C C   . ALA E 5 81  ? 109.940 96.763  98.371  1.00 98.36  ?  81  ALA R C   1 
ATOM   7097 O O   . ALA E 5 81  ? 110.433 95.724  97.921  1.00 98.36  ?  81  ALA R O   1 
ATOM   7098 C CB  . ALA E 5 81  ? 110.367 97.339  100.774 1.00 98.36  ?  81  ALA R CB  1 
ATOM   7099 N N   . ILE E 5 82  ? 108.707 97.160  98.051  1.00 98.25  ?  82  ILE R N   1 
ATOM   7100 C CA  . ILE E 5 82  ? 107.900 96.379  97.118  1.00 98.25  ?  82  ILE R CA  1 
ATOM   7101 C C   . ILE E 5 82  ? 108.539 96.377  95.735  1.00 98.25  ?  82  ILE R C   1 
ATOM   7102 O O   . ILE E 5 82  ? 108.607 95.337  95.068  1.00 98.25  ?  82  ILE R O   1 
ATOM   7103 C CB  . ILE E 5 82  ? 106.459 96.919  97.077  1.00 98.25  ?  82  ILE R CB  1 
ATOM   7104 C CG1 . ILE E 5 82  ? 105.758 96.656  98.413  1.00 98.25  ?  82  ILE R CG1 1 
ATOM   7105 C CG2 . ILE E 5 82  ? 105.687 96.282  95.926  1.00 98.25  ?  82  ILE R CG2 1 
ATOM   7106 C CD1 . ILE E 5 82  ? 104.436 97.382  98.571  1.00 98.25  ?  82  ILE R CD1 1 
ATOM   7107 N N   . SER E 5 83  ? 109.017 97.538  95.281  1.00 98.31  ?  83  SER R N   1 
ATOM   7108 C CA  . SER E 5 83  ? 109.676 97.603  93.981  1.00 98.31  ?  83  SER R CA  1 
ATOM   7109 C C   . SER E 5 83  ? 110.934 96.746  93.962  1.00 98.31  ?  83  SER R C   1 
ATOM   7110 O O   . SER E 5 83  ? 111.198 96.035  92.985  1.00 98.31  ?  83  SER R O   1 
ATOM   7111 C CB  . SER E 5 83  ? 110.012 99.054  93.636  1.00 98.31  ?  83  SER R CB  1 
ATOM   7112 O OG  . SER E 5 83  ? 110.905 99.610  94.587  1.00 98.31  ?  83  SER R OG  1 
ATOM   7113 N N   . ASP E 5 84  ? 111.724 96.797  95.038  1.00 98.32  ?  84  ASP R N   1 
ATOM   7114 C CA  . ASP E 5 84  ? 112.936 95.988  95.099  1.00 98.32  ?  84  ASP R CA  1 
ATOM   7115 C C   . ASP E 5 84  ? 112.605 94.501  95.099  1.00 98.32  ?  84  ASP R C   1 
ATOM   7116 O O   . ASP E 5 84  ? 113.281 93.707  94.436  1.00 98.32  ?  84  ASP R O   1 
ATOM   7117 C CB  . ASP E 5 84  ? 113.750 96.358  96.339  1.00 98.32  ?  84  ASP R CB  1 
ATOM   7118 C CG  . ASP E 5 84  ? 114.187 97.809  96.338  1.00 98.32  ?  84  ASP R CG  1 
ATOM   7119 O OD1 . ASP E 5 84  ? 113.856 98.531  95.374  1.00 98.32  ?  84  ASP R OD1 1 
ATOM   7120 O OD2 . ASP E 5 84  ? 114.863 98.229  97.302  1.00 98.32  ?  84  ASP R OD2 1 
ATOM   7121 N N   . LEU E 5 85  ? 111.562 94.105  95.832  1.00 98.07  ?  85  LEU R N   1 
ATOM   7122 C CA  . LEU E 5 85  ? 111.174 92.699  95.862  1.00 98.07  ?  85  LEU R CA  1 
ATOM   7123 C C   . LEU E 5 85  ? 110.684 92.236  94.497  1.00 98.07  ?  85  LEU R C   1 
ATOM   7124 O O   . LEU E 5 85  ? 110.970 91.110  94.075  1.00 98.07  ?  85  LEU R O   1 
ATOM   7125 C CB  . LEU E 5 85  ? 110.096 92.477  96.924  1.00 98.07  ?  85  LEU R CB  1 
ATOM   7126 C CG  . LEU E 5 85  ? 109.625 91.033  97.116  1.00 98.07  ?  85  LEU R CG  1 
ATOM   7127 C CD1 . LEU E 5 85  ? 110.776 90.144  97.562  1.00 98.07  ?  85  LEU R CD1 1 
ATOM   7128 C CD2 . LEU E 5 85  ? 108.482 90.974  98.117  1.00 98.07  ?  85  LEU R CD2 1 
ATOM   7129 N N   . LEU E 5 86  ? 109.938 93.089  93.791  1.00 97.84  ?  86  LEU R N   1 
ATOM   7130 C CA  . LEU E 5 86  ? 109.490 92.737  92.448  1.00 97.84  ?  86  LEU R CA  1 
ATOM   7131 C C   . LEU E 5 86  ? 110.674 92.599  91.499  1.00 97.84  ?  86  LEU R C   1 
ATOM   7132 O O   . LEU E 5 86  ? 110.725 91.671  90.684  1.00 97.84  ?  86  LEU R O   1 
ATOM   7133 C CB  . LEU E 5 86  ? 108.503 93.785  91.932  1.00 97.84  ?  86  LEU R CB  1 
ATOM   7134 C CG  . LEU E 5 86  ? 107.145 93.840  92.638  1.00 97.84  ?  86  LEU R CG  1 
ATOM   7135 C CD1 . LEU E 5 86  ? 106.316 94.999  92.109  1.00 97.84  ?  86  LEU R CD1 1 
ATOM   7136 C CD2 . LEU E 5 86  ? 106.393 92.527  92.476  1.00 97.84  ?  86  LEU R CD2 1 
ATOM   7137 N N   . PHE E 5 87  ? 111.639 93.517  91.592  1.00 98.30  ?  87  PHE R N   1 
ATOM   7138 C CA  . PHE E 5 87  ? 112.841 93.412  90.771  1.00 98.30  ?  87  PHE R CA  1 
ATOM   7139 C C   . PHE E 5 87  ? 113.604 92.129  91.076  1.00 98.30  ?  87  PHE R C   1 
ATOM   7140 O O   . PHE E 5 87  ? 114.137 91.482  90.167  1.00 98.30  ?  87  PHE R O   1 
ATOM   7141 C CB  . PHE E 5 87  ? 113.733 94.633  90.999  1.00 98.30  ?  87  PHE R CB  1 
ATOM   7142 C CG  . PHE E 5 87  ? 115.076 94.539  90.333  1.00 98.30  ?  87  PHE R CG  1 
ATOM   7143 C CD1 . PHE E 5 87  ? 116.174 94.052  91.023  1.00 98.30  ?  87  PHE R CD1 1 
ATOM   7144 C CD2 . PHE E 5 87  ? 115.242 94.942  89.019  1.00 98.30  ?  87  PHE R CD2 1 
ATOM   7145 C CE1 . PHE E 5 87  ? 117.411 93.966  90.413  1.00 98.30  ?  87  PHE R CE1 1 
ATOM   7146 C CE2 . PHE E 5 87  ? 116.476 94.858  88.406  1.00 98.30  ?  87  PHE R CE2 1 
ATOM   7147 C CZ  . PHE E 5 87  ? 117.562 94.369  89.103  1.00 98.30  ?  87  PHE R CZ  1 
ATOM   7148 N N   . ILE E 5 88  ? 113.665 91.745  92.351  1.00 98.33  ?  88  ILE R N   1 
ATOM   7149 C CA  . ILE E 5 88  ? 114.426 90.564  92.743  1.00 98.33  ?  88  ILE R CA  1 
ATOM   7150 C C   . ILE E 5 88  ? 113.732 89.296  92.260  1.00 98.33  ?  88  ILE R C   1 
ATOM   7151 O O   . ILE E 5 88  ? 114.378 88.367  91.762  1.00 98.33  ?  88  ILE R O   1 
ATOM   7152 C CB  . ILE E 5 88  ? 114.631 90.548  94.268  1.00 98.33  ?  88  ILE R CB  1 
ATOM   7153 C CG1 . ILE E 5 88  ? 115.547 91.698  94.693  1.00 98.33  ?  88  ILE R CG1 1 
ATOM   7154 C CG2 . ILE E 5 88  ? 115.211 89.215  94.713  1.00 98.33  ?  88  ILE R CG2 1 
ATOM   7155 C CD1 . ILE E 5 88  ? 115.395 92.088  96.145  1.00 98.33  ?  88  ILE R CD1 1 
ATOM   7156 N N   . SER E 5 89  ? 112.406 89.236  92.405  1.00 97.74  ?  89  SER R N   1 
ATOM   7157 C CA  . SER E 5 89  ? 111.671 88.043  91.997  1.00 97.74  ?  89  SER R CA  1 
ATOM   7158 C C   . SER E 5 89  ? 111.896 87.720  90.526  1.00 97.74  ?  89  SER R C   1 
ATOM   7159 O O   . SER E 5 89  ? 111.842 86.549  90.133  1.00 97.74  ?  89  SER R O   1 
ATOM   7160 C CB  . SER E 5 89  ? 110.179 88.227  92.277  1.00 97.74  ?  89  SER R CB  1 
ATOM   7161 O OG  . SER E 5 89  ? 109.941 88.436  93.658  1.00 97.74  ?  89  SER R OG  1 
ATOM   7162 N N   . THR E 5 90  ? 112.146 88.735  89.703  1.00 97.70  ?  90  THR R N   1 
ATOM   7163 C CA  . THR E 5 90  ? 112.414 88.544  88.285  1.00 97.70  ?  90  THR R CA  1 
ATOM   7164 C C   . THR E 5 90  ? 113.892 88.321  87.988  1.00 97.70  ?  90  THR R C   1 
ATOM   7165 O O   . THR E 5 90  ? 114.258 88.168  86.818  1.00 97.70  ?  90  THR R O   1 
ATOM   7166 C CB  . THR E 5 90  ? 111.912 89.753  87.488  1.00 97.70  ?  90  THR R CB  1 
ATOM   7167 O OG1 . THR E 5 90  ? 112.588 90.937  87.931  1.00 97.70  ?  90  THR R OG1 1 
ATOM   7168 C CG2 . THR E 5 90  ? 110.411 89.929  87.672  1.00 97.70  ?  90  THR R CG2 1 
ATOM   7169 N N   . LEU E 5 91  ? 114.743 88.300  89.011  1.00 98.06  ?  91  LEU R N   1 
ATOM   7170 C CA  . LEU E 5 91  ? 116.180 88.136  88.830  1.00 98.06  ?  91  LEU R CA  1 
ATOM   7171 C C   . LEU E 5 91  ? 116.562 86.680  88.573  1.00 98.06  ?  91  LEU R C   1 
ATOM   7172 O O   . LEU E 5 91  ? 117.293 86.402  87.613  1.00 98.06  ?  91  LEU R O   1 
ATOM   7173 C CB  . LEU E 5 91  ? 116.928 88.664  90.056  1.00 98.06  ?  91  LEU R CB  1 
ATOM   7174 C CG  . LEU E 5 91  ? 118.456 88.666  89.961  1.00 98.06  ?  91  LEU R CG  1 
ATOM   7175 C CD1 . LEU E 5 91  ? 118.927 89.553  88.818  1.00 98.06  ?  91  LEU R CD1 1 
ATOM   7176 C CD2 . LEU E 5 91  ? 119.070 89.116  91.277  1.00 98.06  ?  91  LEU R CD2 1 
ATOM   7177 N N   . PRO E 5 92  ? 116.105 85.723  89.389  1.00 98.14  ?  92  PRO R N   1 
ATOM   7178 C CA  . PRO E 5 92  ? 116.584 84.342  89.204  1.00 98.14  ?  92  PRO R CA  1 
ATOM   7179 C C   . PRO E 5 92  ? 116.186 83.735  87.872  1.00 98.14  ?  92  PRO R C   1 
ATOM   7180 O O   . PRO E 5 92  ? 116.832 82.780  87.422  1.00 98.14  ?  92  PRO R O   1 
ATOM   7181 C CB  . PRO E 5 92  ? 115.954 83.588  90.384  1.00 98.14  ?  92  PRO R CB  1 
ATOM   7182 C CG  . PRO E 5 92  ? 114.775 84.389  90.766  1.00 98.14  ?  92  PRO R CG  1 
ATOM   7183 C CD  . PRO E 5 92  ? 115.133 85.817  90.493  1.00 98.14  ?  92  PRO R CD  1 
ATOM   7184 N N   . PHE E 5 93  ? 115.144 84.256  87.222  1.00 97.92  ?  93  PHE R N   1 
ATOM   7185 C CA  . PHE E 5 93  ? 114.784 83.756  85.899  1.00 97.92  ?  93  PHE R CA  1 
ATOM   7186 C C   . PHE E 5 93  ? 115.908 84.000  84.901  1.00 97.92  ?  93  PHE R C   1 
ATOM   7187 O O   . PHE E 5 93  ? 116.268 83.106  84.126  1.00 97.92  ?  93  PHE R O   1 
ATOM   7188 C CB  . PHE E 5 93  ? 113.490 84.414  85.423  1.00 97.92  ?  93  PHE R CB  1 
ATOM   7189 C CG  . PHE E 5 93  ? 112.281 84.023  86.225  1.00 97.92  ?  93  PHE R CG  1 
ATOM   7190 C CD1 . PHE E 5 93  ? 111.912 84.747  87.346  1.00 97.92  ?  93  PHE R CD1 1 
ATOM   7191 C CD2 . PHE E 5 93  ? 111.514 82.930  85.857  1.00 97.92  ?  93  PHE R CD2 1 
ATOM   7192 C CE1 . PHE E 5 93  ? 110.800 84.389  88.085  1.00 97.92  ?  93  PHE R CE1 1 
ATOM   7193 C CE2 . PHE E 5 93  ? 110.402 82.567  86.591  1.00 97.92  ?  93  PHE R CE2 1 
ATOM   7194 C CZ  . PHE E 5 93  ? 110.044 83.297  87.706  1.00 97.92  ?  93  PHE R CZ  1 
ATOM   7195 N N   . ARG E 5 94  ? 116.485 85.204  84.913  1.00 97.54  ?  94  ARG R N   1 
ATOM   7196 C CA  . ARG E 5 94  ? 117.587 85.501  84.005  1.00 97.54  ?  94  ARG R CA  1 
ATOM   7197 C C   . ARG E 5 94  ? 118.821 84.678  84.356  1.00 97.54  ?  94  ARG R C   1 
ATOM   7198 O O   . ARG E 5 94  ? 119.565 84.251  83.464  1.00 97.54  ?  94  ARG R O   1 
ATOM   7199 C CB  . ARG E 5 94  ? 117.908 86.996  84.041  1.00 97.54  ?  94  ARG R CB  1 
ATOM   7200 C CG  . ARG E 5 94  ? 116.679 87.896  84.019  1.00 97.54  ?  94  ARG R CG  1 
ATOM   7201 C CD  . ARG E 5 94  ? 116.934 89.185  83.252  1.00 97.54  ?  94  ARG R CD  1 
ATOM   7202 N NE  . ARG E 5 94  ? 118.208 89.803  83.605  1.00 97.54  ?  94  ARG R NE  1 
ATOM   7203 C CZ  . ARG E 5 94  ? 118.742 90.835  82.958  1.00 97.54  ?  94  ARG R CZ  1 
ATOM   7204 N NH1 . ARG E 5 94  ? 118.115 91.369  81.918  1.00 97.54  1  94  ARG R NH1 1 
ATOM   7205 N NH2 . ARG E 5 94  ? 119.907 91.332  83.350  1.00 97.54  ?  94  ARG R NH2 1 
ATOM   7206 N N   . ALA E 5 95  ? 119.056 84.449  85.650  1.00 97.87  ?  95  ALA R N   1 
ATOM   7207 C CA  . ALA E 5 95  ? 120.171 83.601  86.056  1.00 97.87  ?  95  ALA R CA  1 
ATOM   7208 C C   . ALA E 5 95  ? 120.007 82.188  85.513  1.00 97.87  ?  95  ALA R C   1 
ATOM   7209 O O   . ALA E 5 95  ? 120.954 81.610  84.967  1.00 97.87  ?  95  ALA R O   1 
ATOM   7210 C CB  . ALA E 5 95  ? 120.285 83.580  87.580  1.00 97.87  ?  95  ALA R CB  1 
ATOM   7211 N N   . ASP E 5 96  ? 118.809 81.616  85.652  1.00 98.02  ?  96  ASP R N   1 
ATOM   7212 C CA  . ASP E 5 96  ? 118.561 80.285  85.109  1.00 98.02  ?  96  ASP R CA  1 
ATOM   7213 C C   . ASP E 5 96  ? 118.714 80.277  83.593  1.00 98.02  ?  96  ASP R C   1 
ATOM   7214 O O   . ASP E 5 96  ? 119.271 79.333  83.022  1.00 98.02  ?  96  ASP R O   1 
ATOM   7215 C CB  . ASP E 5 96  ? 117.165 79.809  85.513  1.00 98.02  ?  96  ASP R CB  1 
ATOM   7216 C CG  . ASP E 5 96  ? 116.951 78.328  85.254  1.00 98.02  ?  96  ASP R CG  1 
ATOM   7217 O OD1 . ASP E 5 96  ? 117.578 77.782  84.322  1.00 98.02  ?  96  ASP R OD1 1 
ATOM   7218 O OD2 . ASP E 5 96  ? 116.151 77.708  85.986  1.00 98.02  ?  96  ASP R OD2 1 
ATOM   7219 N N   . TYR E 5 97  ? 118.223 81.323  82.924  1.00 97.19  ?  97  TYR R N   1 
ATOM   7220 C CA  . TYR E 5 97  ? 118.376 81.416  81.476  1.00 97.19  ?  97  TYR R CA  1 
ATOM   7221 C C   . TYR E 5 97  ? 119.846 81.368  81.077  1.00 97.19  ?  97  TYR R C   1 
ATOM   7222 O O   . TYR E 5 97  ? 120.250 80.548  80.244  1.00 97.19  ?  97  TYR R O   1 
ATOM   7223 C CB  . TYR E 5 97  ? 117.723 82.701  80.964  1.00 97.19  ?  97  TYR R CB  1 
ATOM   7224 C CG  . TYR E 5 97  ? 118.101 83.055  79.543  1.00 97.19  ?  97  TYR R CG  1 
ATOM   7225 C CD1 . TYR E 5 97  ? 117.444 82.479  78.466  1.00 97.19  ?  97  TYR R CD1 1 
ATOM   7226 C CD2 . TYR E 5 97  ? 119.115 83.967  79.280  1.00 97.19  ?  97  TYR R CD2 1 
ATOM   7227 C CE1 . TYR E 5 97  ? 117.786 82.798  77.165  1.00 97.19  ?  97  TYR R CE1 1 
ATOM   7228 C CE2 . TYR E 5 97  ? 119.464 84.293  77.983  1.00 97.19  ?  97  TYR R CE2 1 
ATOM   7229 C CZ  . TYR E 5 97  ? 118.797 83.705  76.930  1.00 97.19  ?  97  TYR R CZ  1 
ATOM   7230 O OH  . TYR E 5 97  ? 119.140 84.026  75.637  1.00 97.19  ?  97  TYR R OH  1 
ATOM   7231 N N   . TYR E 5 98  ? 120.664 82.244  81.665  1.00 96.36  ?  98  TYR R N   1 
ATOM   7232 C CA  . TYR E 5 98  ? 122.081 82.287  81.320  1.00 96.36  ?  98  TYR R CA  1 
ATOM   7233 C C   . TYR E 5 98  ? 122.836 81.054  81.799  1.00 96.36  ?  98  TYR R C   1 
ATOM   7234 O O   . TYR E 5 98  ? 123.933 80.784  81.299  1.00 96.36  ?  98  TYR R O   1 
ATOM   7235 C CB  . TYR E 5 98  ? 122.729 83.545  81.901  1.00 96.36  ?  98  TYR R CB  1 
ATOM   7236 C CG  . TYR E 5 98  ? 122.412 84.810  81.134  1.00 96.36  ?  98  TYR R CG  1 
ATOM   7237 C CD1 . TYR E 5 98  ? 123.057 85.099  79.939  1.00 96.36  ?  98  TYR R CD1 1 
ATOM   7238 C CD2 . TYR E 5 98  ? 121.474 85.718  81.608  1.00 96.36  ?  98  TYR R CD2 1 
ATOM   7239 C CE1 . TYR E 5 98  ? 122.773 86.254  79.234  1.00 96.36  ?  98  TYR R CE1 1 
ATOM   7240 C CE2 . TYR E 5 98  ? 121.184 86.875  80.911  1.00 96.36  ?  98  TYR R CE2 1 
ATOM   7241 C CZ  . TYR E 5 98  ? 121.836 87.139  79.725  1.00 96.36  ?  98  TYR R CZ  1 
ATOM   7242 O OH  . TYR E 5 98  ? 121.551 88.290  79.028  1.00 96.36  ?  98  TYR R OH  1 
ATOM   7243 N N   . LEU E 5 99  ? 122.279 80.301  82.750  1.00 97.03  ?  99  LEU R N   1 
ATOM   7244 C CA  . LEU E 5 99  ? 122.980 79.129  83.265  1.00 97.03  ?  99  LEU R CA  1 
ATOM   7245 C C   . LEU E 5 99  ? 123.004 78.001  82.240  1.00 97.03  ?  99  LEU R C   1 
ATOM   7246 O O   . LEU E 5 99  ? 124.000 77.277  82.131  1.00 97.03  ?  99  LEU R O   1 
ATOM   7247 C CB  . LEU E 5 99  ? 122.324 78.659  84.564  1.00 97.03  ?  99  LEU R CB  1 
ATOM   7248 C CG  . LEU E 5 99  ? 122.924 77.409  85.213  1.00 97.03  ?  99  LEU R CG  1 
ATOM   7249 C CD1 . LEU E 5 99  ? 124.393 77.620  85.548  1.00 97.03  ?  99  LEU R CD1 1 
ATOM   7250 C CD2 . LEU E 5 99  ? 122.139 77.030  86.459  1.00 97.03  ?  99  LEU R CD2 1 
ATOM   7251 N N   . ARG E 5 100 ? 121.920 77.836  81.479  1.00 95.71  ?  100 ARG R N   1 
ATOM   7252 C CA  . ARG E 5 100 ? 121.798 76.750  80.512  1.00 95.71  ?  100 ARG R CA  1 
ATOM   7253 C C   . ARG E 5 100 ? 122.232 77.159  79.109  1.00 95.71  ?  100 ARG R C   1 
ATOM   7254 O O   . ARG E 5 100 ? 121.728 76.606  78.122  1.00 95.71  ?  100 ARG R O   1 
ATOM   7255 C CB  . ARG E 5 100 ? 120.362 76.222  80.494  1.00 95.71  ?  100 ARG R CB  1 
ATOM   7256 C CG  . ARG E 5 100 ? 119.303 77.284  80.245  1.00 95.71  ?  100 ARG R CG  1 
ATOM   7257 C CD  . ARG E 5 100 ? 117.918 76.671  80.086  1.00 95.71  ?  100 ARG R CD  1 
ATOM   7258 N NE  . ARG E 5 100 ? 117.523 75.878  81.249  1.00 95.71  ?  100 ARG R NE  1 
ATOM   7259 C CZ  . ARG E 5 100 ? 117.721 74.568  81.378  1.00 95.71  ?  100 ARG R CZ  1 
ATOM   7260 N NH1 . ARG E 5 100 ? 118.316 73.874  80.415  1.00 95.71  1  100 ARG R NH1 1 
ATOM   7261 N NH2 . ARG E 5 100 ? 117.321 73.946  82.479  1.00 95.71  ?  100 ARG R NH2 1 
ATOM   7262 N N   . GLY E 5 101 ? 123.153 78.111  78.992  1.00 93.53  ?  101 GLY R N   1 
ATOM   7263 C CA  . GLY E 5 101 ? 123.680 78.501  77.698  1.00 93.53  ?  101 GLY R CA  1 
ATOM   7264 C C   . GLY E 5 101 ? 122.733 79.362  76.888  1.00 93.53  ?  101 GLY R C   1 
ATOM   7265 O O   . GLY E 5 101 ? 122.532 79.120  75.694  1.00 93.53  ?  101 GLY R O   1 
ATOM   7266 N N   . SER E 5 102 ? 122.147 80.374  77.527  1.00 93.67  ?  102 SER R N   1 
ATOM   7267 C CA  . SER E 5 102 ? 121.271 81.328  76.849  1.00 93.67  ?  102 SER R CA  1 
ATOM   7268 C C   . SER E 5 102 ? 120.106 80.616  76.162  1.00 93.67  ?  102 SER R C   1 
ATOM   7269 O O   . SER E 5 102 ? 119.859 80.786  74.966  1.00 93.67  ?  102 SER R O   1 
ATOM   7270 C CB  . SER E 5 102 ? 122.062 82.174  75.848  1.00 93.67  ?  102 SER R CB  1 
ATOM   7271 O OG  . SER E 5 102 ? 123.092 82.900  76.496  1.00 93.67  ?  102 SER R OG  1 
ATOM   7272 N N   . ASN E 5 103 ? 119.385 79.807  76.935  1.00 95.30  ?  103 ASN R N   1 
ATOM   7273 C CA  . ASN E 5 103 ? 118.205 79.095  76.458  1.00 95.30  ?  103 ASN R CA  1 
ATOM   7274 C C   . ASN E 5 103 ? 117.015 79.501  77.314  1.00 95.30  ?  103 ASN R C   1 
ATOM   7275 O O   . ASN E 5 103 ? 117.022 79.289  78.531  1.00 95.30  ?  103 ASN R O   1 
ATOM   7276 C CB  . ASN E 5 103 ? 118.416 77.580  76.511  1.00 95.30  ?  103 ASN R CB  1 
ATOM   7277 C CG  . ASN E 5 103 ? 119.499 77.108  75.562  1.00 95.30  ?  103 ASN R CG  1 
ATOM   7278 O OD1 . ASN E 5 103 ? 119.222 76.733  74.423  1.00 95.30  ?  103 ASN R OD1 1 
ATOM   7279 N ND2 . ASN E 5 103 ? 120.742 77.126  76.027  1.00 95.30  ?  103 ASN R ND2 1 
ATOM   7280 N N   . TRP E 5 104 ? 116.002 80.086  76.680  1.00 96.09  ?  104 TRP R N   1 
ATOM   7281 C CA  . TRP E 5 104 ? 114.796 80.539  77.365  1.00 96.09  ?  104 TRP R CA  1 
ATOM   7282 C C   . TRP E 5 104 ? 113.738 79.449  77.243  1.00 96.09  ?  104 TRP R C   1 
ATOM   7283 O O   . TRP E 5 104 ? 113.209 79.206  76.153  1.00 96.09  ?  104 TRP R O   1 
ATOM   7284 C CB  . TRP E 5 104 ? 114.303 81.859  76.777  1.00 96.09  ?  104 TRP R CB  1 
ATOM   7285 C CG  . TRP E 5 104 ? 113.142 82.451  77.513  1.00 96.09  ?  104 TRP R CG  1 
ATOM   7286 C CD1 . TRP E 5 104 ? 111.823 82.347  77.183  1.00 96.09  ?  104 TRP R CD1 1 
ATOM   7287 C CD2 . TRP E 5 104 ? 113.196 83.243  78.706  1.00 96.09  ?  104 TRP R CD2 1 
ATOM   7288 N NE1 . TRP E 5 104 ? 111.051 83.024  78.095  1.00 96.09  ?  104 TRP R NE1 1 
ATOM   7289 C CE2 . TRP E 5 104 ? 111.870 83.583  79.041  1.00 96.09  ?  104 TRP R CE2 1 
ATOM   7290 C CE3 . TRP E 5 104 ? 114.235 83.697  79.523  1.00 96.09  ?  104 TRP R CE3 1 
ATOM   7291 C CZ2 . TRP E 5 104 ? 111.557 84.355  80.158  1.00 96.09  ?  104 TRP R CZ2 1 
ATOM   7292 C CZ3 . TRP E 5 104 ? 113.922 84.464  80.631  1.00 96.09  ?  104 TRP R CZ3 1 
ATOM   7293 C CH2 . TRP E 5 104 ? 112.594 84.785  80.938  1.00 96.09  ?  104 TRP R CH2 1 
ATOM   7294 N N   . ILE E 5 105 ? 113.431 78.793  78.363  1.00 96.40  ?  105 ILE R N   1 
ATOM   7295 C CA  . ILE E 5 105 ? 112.467 77.698  78.355  1.00 96.40  ?  105 ILE R CA  1 
ATOM   7296 C C   . ILE E 5 105 ? 111.032 78.173  78.559  1.00 96.40  ?  105 ILE R C   1 
ATOM   7297 O O   . ILE E 5 105 ? 110.094 77.433  78.230  1.00 96.40  ?  105 ILE R O   1 
ATOM   7298 C CB  . ILE E 5 105 ? 112.819 76.651  79.428  1.00 96.40  ?  105 ILE R CB  1 
ATOM   7299 C CG1 . ILE E 5 105 ? 112.805 77.279  80.826  1.00 96.40  ?  105 ILE R CG1 1 
ATOM   7300 C CG2 . ILE E 5 105 ? 114.179 76.034  79.134  1.00 96.40  ?  105 ILE R CG2 1 
ATOM   7301 C CD1 . ILE E 5 105 ? 113.071 76.289  81.942  1.00 96.40  ?  105 ILE R CD1 1 
ATOM   7302 N N   . PHE E 5 106 ? 110.833 79.376  79.088  1.00 96.07  ?  106 PHE R N   1 
ATOM   7303 C CA  . PHE E 5 106 ? 109.494 79.899  79.295  1.00 96.07  ?  106 PHE R CA  1 
ATOM   7304 C C   . PHE E 5 106 ? 108.937 80.465  77.990  1.00 96.07  ?  106 PHE R C   1 
ATOM   7305 O O   . PHE E 5 106 ? 109.588 80.448  76.942  1.00 96.07  ?  106 PHE R O   1 
ATOM   7306 C CB  . PHE E 5 106 ? 109.501 80.972  80.384  1.00 96.07  ?  106 PHE R CB  1 
ATOM   7307 C CG  . PHE E 5 106 ? 110.096 80.511  81.684  1.00 96.07  ?  106 PHE R CG  1 
ATOM   7308 C CD1 . PHE E 5 106 ? 109.303 79.921  82.654  1.00 96.07  ?  106 PHE R CD1 1 
ATOM   7309 C CD2 . PHE E 5 106 ? 111.449 80.669  81.937  1.00 96.07  ?  106 PHE R CD2 1 
ATOM   7310 C CE1 . PHE E 5 106 ? 109.848 79.497  83.852  1.00 96.07  ?  106 PHE R CE1 1 
ATOM   7311 C CE2 . PHE E 5 106 ? 111.999 80.246  83.132  1.00 96.07  ?  106 PHE R CE2 1 
ATOM   7312 C CZ  . PHE E 5 106 ? 111.198 79.660  84.090  1.00 96.07  ?  106 PHE R CZ  1 
ATOM   7313 N N   . GLY E 5 107 ? 107.709 80.968  78.063  1.00 94.78  ?  107 GLY R N   1 
ATOM   7314 C CA  . GLY E 5 107 ? 107.073 81.549  76.900  1.00 94.78  ?  107 GLY R CA  1 
ATOM   7315 C C   . GLY E 5 107 ? 107.589 82.943  76.596  1.00 94.78  ?  107 GLY R C   1 
ATOM   7316 O O   . GLY E 5 107 ? 108.305 83.571  77.378  1.00 94.78  ?  107 GLY R O   1 
ATOM   7317 N N   . ASP E 5 108 ? 107.206 83.437  75.416  1.00 94.00  ?  108 ASP R N   1 
ATOM   7318 C CA  . ASP E 5 108 ? 107.609 84.781  75.018  1.00 94.00  ?  108 ASP R CA  1 
ATOM   7319 C C   . ASP E 5 108 ? 107.003 85.829  75.942  1.00 94.00  ?  108 ASP R C   1 
ATOM   7320 O O   . ASP E 5 108 ? 107.644 86.841  76.253  1.00 94.00  ?  108 ASP R O   1 
ATOM   7321 C CB  . ASP E 5 108 ? 107.200 85.042  73.568  1.00 94.00  ?  108 ASP R CB  1 
ATOM   7322 C CG  . ASP E 5 108 ? 107.732 86.361  73.040  1.00 94.00  ?  108 ASP R CG  1 
ATOM   7323 O OD1 . ASP E 5 108 ? 108.508 87.023  73.761  1.00 94.00  ?  108 ASP R OD1 1 
ATOM   7324 O OD2 . ASP E 5 108 ? 107.374 86.735  71.904  1.00 94.00  ?  108 ASP R OD2 1 
ATOM   7325 N N   . LEU E 5 109 ? 105.763 85.608  76.387  1.00 94.87  ?  109 LEU R N   1 
ATOM   7326 C CA  . LEU E 5 109 ? 105.148 86.529  77.334  1.00 94.87  ?  109 LEU R CA  1 
ATOM   7327 C C   . LEU E 5 109 ? 105.969 86.636  78.611  1.00 94.87  ?  109 LEU R C   1 
ATOM   7328 O O   . LEU E 5 109 ? 106.087 87.725  79.183  1.00 94.87  ?  109 LEU R O   1 
ATOM   7329 C CB  . LEU E 5 109 ? 103.722 86.079  77.656  1.00 94.87  ?  109 LEU R CB  1 
ATOM   7330 C CG  . LEU E 5 109 ? 102.927 86.978  78.607  1.00 94.87  ?  109 LEU R CG  1 
ATOM   7331 C CD1 . LEU E 5 109 ? 102.756 88.373  78.023  1.00 94.87  ?  109 LEU R CD1 1 
ATOM   7332 C CD2 . LEU E 5 109 ? 101.574 86.360  78.923  1.00 94.87  ?  109 LEU R CD2 1 
ATOM   7333 N N   . ALA E 5 110 ? 106.547 85.523  79.069  1.00 95.86  ?  110 ALA R N   1 
ATOM   7334 C CA  . ALA E 5 110 ? 107.396 85.570  80.254  1.00 95.86  ?  110 ALA R CA  1 
ATOM   7335 C C   . ALA E 5 110 ? 108.628 86.431  80.010  1.00 95.86  ?  110 ALA R C   1 
ATOM   7336 O O   . ALA E 5 110 ? 109.011 87.237  80.865  1.00 95.86  ?  110 ALA R O   1 
ATOM   7337 C CB  . ALA E 5 110 ? 107.803 84.155  80.663  1.00 95.86  ?  110 ALA R CB  1 
ATOM   7338 N N   . CYS E 5 111 ? 109.265 86.272  78.847  1.00 95.55  ?  111 CYS R N   1 
ATOM   7339 C CA  . CYS E 5 111 ? 110.422 87.097  78.511  1.00 95.55  ?  111 CYS R CA  1 
ATOM   7340 C C   . CYS E 5 111 ? 110.050 88.575  78.502  1.00 95.55  ?  111 CYS R C   1 
ATOM   7341 O O   . CYS E 5 111 ? 110.770 89.415  79.057  1.00 95.55  ?  111 CYS R O   1 
ATOM   7342 C CB  . CYS E 5 111 ? 110.983 86.668  77.152  1.00 95.55  ?  111 CYS R CB  1 
ATOM   7343 S SG  . CYS E 5 111 ? 112.428 87.602  76.588  1.00 95.55  ?  111 CYS R SG  1 
ATOM   7344 N N   . ARG E 5 112 ? 108.922 88.908  77.871  1.00 94.40  ?  112 ARG R N   1 
ATOM   7345 C CA  . ARG E 5 112 ? 108.478 90.298  77.822  1.00 94.40  ?  112 ARG R CA  1 
ATOM   7346 C C   . ARG E 5 112 ? 108.241 90.844  79.224  1.00 94.40  ?  112 ARG R C   1 
ATOM   7347 O O   . ARG E 5 112 ? 108.717 91.933  79.571  1.00 94.40  ?  112 ARG R O   1 
ATOM   7348 C CB  . ARG E 5 112 ? 107.203 90.411  76.985  1.00 94.40  ?  112 ARG R CB  1 
ATOM   7349 C CG  . ARG E 5 112 ? 107.355 89.963  75.540  1.00 94.40  ?  112 ARG R CG  1 
ATOM   7350 C CD  . ARG E 5 112 ? 105.997 89.771  74.880  1.00 94.40  ?  112 ARG R CD  1 
ATOM   7351 N NE  . ARG E 5 112 ? 106.106 89.183  73.546  1.00 94.40  ?  112 ARG R NE  1 
ATOM   7352 C CZ  . ARG E 5 112 ? 106.267 89.878  72.423  1.00 94.40  ?  112 ARG R CZ  1 
ATOM   7353 N NH1 . ARG E 5 112 ? 106.346 91.202  72.453  1.00 94.40  1  112 ARG R NH1 1 
ATOM   7354 N NH2 . ARG E 5 112 ? 106.353 89.244  71.262  1.00 94.40  ?  112 ARG R NH2 1 
ATOM   7355 N N   . ILE E 5 113 ? 107.495 90.100  80.045  1.00 95.92  ?  113 ILE R N   1 
ATOM   7356 C CA  . ILE E 5 113 ? 107.160 90.575  81.384  1.00 95.92  ?  113 ILE R CA  1 
ATOM   7357 C C   . ILE E 5 113 ? 108.421 90.750  82.218  1.00 95.92  ?  113 ILE R C   1 
ATOM   7358 O O   . ILE E 5 113 ? 108.541 91.708  82.989  1.00 95.92  ?  113 ILE R O   1 
ATOM   7359 C CB  . ILE E 5 113 ? 106.165 89.611  82.059  1.00 95.92  ?  113 ILE R CB  1 
ATOM   7360 C CG1 . ILE E 5 113 ? 104.815 89.632  81.332  1.00 95.92  ?  113 ILE R CG1 1 
ATOM   7361 C CG2 . ILE E 5 113 ? 105.990 89.965  83.529  1.00 95.92  ?  113 ILE R CG2 1 
ATOM   7362 C CD1 . ILE E 5 113 ? 104.056 90.944  81.446  1.00 95.92  ?  113 ILE R CD1 1 
ATOM   7363 N N   . MET E 5 114 ? 109.385 89.838  82.076  1.00 95.28  ?  114 MET R N   1 
ATOM   7364 C CA  . MET E 5 114 ? 110.619 89.950  82.847  1.00 95.28  ?  114 MET R CA  1 
ATOM   7365 C C   . MET E 5 114 ? 111.425 91.169  82.418  1.00 95.28  ?  114 MET R C   1 
ATOM   7366 O O   . MET E 5 114 ? 111.878 91.953  83.264  1.00 95.28  ?  114 MET R O   1 
ATOM   7367 C CB  . MET E 5 114 ? 111.450 88.677  82.685  1.00 95.28  ?  114 MET R CB  1 
ATOM   7368 C CG  . MET E 5 114 ? 112.020 88.133  83.986  1.00 95.28  ?  114 MET R CG  1 
ATOM   7369 S SD  . MET E 5 114 ? 110.747 87.565  85.133  1.00 95.28  ?  114 MET R SD  1 
ATOM   7370 C CE  . MET E 5 114 ? 110.007 86.227  84.199  1.00 95.28  ?  114 MET R CE  1 
ATOM   7371 N N   . SER E 5 115 ? 111.625 91.337  81.107  1.00 91.39  ?  115 SER R N   1 
ATOM   7372 C CA  . SER E 5 115 ? 112.375 92.488  80.616  1.00 91.39  ?  115 SER R CA  1 
ATOM   7373 C C   . SER E 5 115 ? 111.704 93.793  81.024  1.00 91.39  ?  115 SER R C   1 
ATOM   7374 O O   . SER E 5 115 ? 112.382 94.793  81.287  1.00 91.39  ?  115 SER R O   1 
ATOM   7375 C CB  . SER E 5 115 ? 112.516 92.411  79.096  1.00 91.39  ?  115 SER R CB  1 
ATOM   7376 O OG  . SER E 5 115 ? 113.205 91.236  78.706  1.00 91.39  ?  115 SER R OG  1 
ATOM   7377 N N   . TYR E 5 116 ? 110.372 93.802  81.083  1.00 94.92  ?  116 TYR R N   1 
ATOM   7378 C CA  . TYR E 5 116 ? 109.656 95.013  81.469  1.00 94.92  ?  116 TYR R CA  1 
ATOM   7379 C C   . TYR E 5 116 ? 109.797 95.285  82.963  1.00 94.92  ?  116 TYR R C   1 
ATOM   7380 O O   . TYR E 5 116 ? 110.109 96.411  83.374  1.00 94.92  ?  116 TYR R O   1 
ATOM   7381 C CB  . TYR E 5 116 ? 108.185 94.878  81.072  1.00 94.92  ?  116 TYR R CB  1 
ATOM   7382 C CG  . TYR E 5 116 ? 107.287 95.991  81.557  1.00 94.92  ?  116 TYR R CG  1 
ATOM   7383 C CD1 . TYR E 5 116 ? 107.187 97.185  80.856  1.00 94.92  ?  116 TYR R CD1 1 
ATOM   7384 C CD2 . TYR E 5 116 ? 106.523 95.839  82.706  1.00 94.92  ?  116 TYR R CD2 1 
ATOM   7385 C CE1 . TYR E 5 116 ? 106.360 98.201  81.293  1.00 94.92  ?  116 TYR R CE1 1 
ATOM   7386 C CE2 . TYR E 5 116 ? 105.694 96.849  83.150  1.00 94.92  ?  116 TYR R CE2 1 
ATOM   7387 C CZ  . TYR E 5 116 ? 105.615 98.027  82.440  1.00 94.92  ?  116 TYR R CZ  1 
ATOM   7388 O OH  . TYR E 5 116 ? 104.789 99.033  82.880  1.00 94.92  ?  116 TYR R OH  1 
ATOM   7389 N N   . SER E 5 117 ? 109.562 94.260  83.788  1.00 96.42  ?  117 SER R N   1 
ATOM   7390 C CA  . SER E 5 117 ? 109.588 94.414  85.235  1.00 96.42  ?  117 SER R CA  1 
ATOM   7391 C C   . SER E 5 117 ? 110.976 94.748  85.757  1.00 96.42  ?  117 SER R C   1 
ATOM   7392 O O   . SER E 5 117 ? 111.088 95.459  86.762  1.00 96.42  ?  117 SER R O   1 
ATOM   7393 C CB  . SER E 5 117 ? 109.080 93.134  85.903  1.00 96.42  ?  117 SER R CB  1 
ATOM   7394 O OG  . SER E 5 117 ? 109.198 93.210  87.313  1.00 96.42  ?  117 SER R OG  1 
ATOM   7395 N N   . LEU E 5 118 ? 112.030 94.255  85.110  1.00 95.27  ?  118 LEU R N   1 
ATOM   7396 C CA  . LEU E 5 118 ? 113.382 94.580  85.543  1.00 95.27  ?  118 LEU R CA  1 
ATOM   7397 C C   . LEU E 5 118 ? 113.578 96.092  85.538  1.00 95.27  ?  118 LEU R C   1 
ATOM   7398 O O   . LEU E 5 118 ? 113.819 96.704  86.586  1.00 95.27  ?  118 LEU R O   1 
ATOM   7399 C CB  . LEU E 5 118 ? 114.410 93.894  84.636  1.00 95.27  ?  118 LEU R CB  1 
ATOM   7400 C CG  . LEU E 5 118 ? 115.882 93.931  85.060  1.00 95.27  ?  118 LEU R CG  1 
ATOM   7401 C CD1 . LEU E 5 118 ? 116.672 92.884  84.293  1.00 95.27  ?  118 LEU R CD1 1 
ATOM   7402 C CD2 . LEU E 5 118 ? 116.499 95.309  84.851  1.00 95.27  ?  118 LEU R CD2 1 
ATOM   7403 N N   . TYR E 5 119 ? 113.446 96.705  84.361  1.00 94.66  ?  119 TYR R N   1 
ATOM   7404 C CA  . TYR E 5 119 ? 113.781 98.116  84.219  1.00 94.66  ?  119 TYR R CA  1 
ATOM   7405 C C   . TYR E 5 119 ? 112.723 99.032  84.822  1.00 94.66  ?  119 TYR R C   1 
ATOM   7406 O O   . TYR E 5 119 ? 113.075 100.067 85.404  1.00 94.66  ?  119 TYR R O   1 
ATOM   7407 C CB  . TYR E 5 119 ? 114.004 98.450  82.744  1.00 94.66  ?  119 TYR R CB  1 
ATOM   7408 C CG  . TYR E 5 119 ? 115.154 97.679  82.139  1.00 94.66  ?  119 TYR R CG  1 
ATOM   7409 C CD1 . TYR E 5 119 ? 116.460 98.129  82.266  1.00 94.66  ?  119 TYR R CD1 1 
ATOM   7410 C CD2 . TYR E 5 119 ? 114.934 96.493  81.455  1.00 94.66  ?  119 TYR R CD2 1 
ATOM   7411 C CE1 . TYR E 5 119 ? 117.514 97.422  81.721  1.00 94.66  ?  119 TYR R CE1 1 
ATOM   7412 C CE2 . TYR E 5 119 ? 115.980 95.780  80.908  1.00 94.66  ?  119 TYR R CE2 1 
ATOM   7413 C CZ  . TYR E 5 119 ? 117.268 96.248  81.044  1.00 94.66  ?  119 TYR R CZ  1 
ATOM   7414 O OH  . TYR E 5 119 ? 118.313 95.540  80.497  1.00 94.66  ?  119 TYR R OH  1 
ATOM   7415 N N   . VAL E 5 120 ? 111.434 98.692  84.708  1.00 97.12  ?  120 VAL R N   1 
ATOM   7416 C CA  . VAL E 5 120 ? 110.421 99.534  85.333  1.00 97.12  ?  120 VAL R CA  1 
ATOM   7417 C C   . VAL E 5 120 ? 110.632 99.574  86.841  1.00 97.12  ?  120 VAL R C   1 
ATOM   7418 O O   . VAL E 5 120 ? 110.528 100.635 87.468  1.00 97.12  ?  120 VAL R O   1 
ATOM   7419 C CB  . VAL E 5 120 ? 109.007 99.046  84.965  1.00 97.12  ?  120 VAL R CB  1 
ATOM   7420 C CG1 . VAL E 5 120 ? 108.694 97.729  85.647  1.00 97.12  ?  120 VAL R CG1 1 
ATOM   7421 C CG2 . VAL E 5 120 ? 107.966 100.098 85.321  1.00 97.12  ?  120 VAL R CG2 1 
ATOM   7422 N N   . ASN E 5 121 ? 110.966 98.430  87.442  1.00 98.13  ?  121 ASN R N   1 
ATOM   7423 C CA  . ASN E 5 121 ? 111.218 98.393  88.877  1.00 98.13  ?  121 ASN R CA  1 
ATOM   7424 C C   . ASN E 5 121 ? 112.510 99.108  89.244  1.00 98.13  ?  121 ASN R C   1 
ATOM   7425 O O   . ASN E 5 121 ? 112.559 99.787  90.273  1.00 98.13  ?  121 ASN R O   1 
ATOM   7426 C CB  . ASN E 5 121 ? 111.266 96.947  89.371  1.00 98.13  ?  121 ASN R CB  1 
ATOM   7427 C CG  . ASN E 5 121 ? 109.919 96.258  89.286  1.00 98.13  ?  121 ASN R CG  1 
ATOM   7428 O OD1 . ASN E 5 121 ? 108.873 96.908  89.307  1.00 98.13  ?  121 ASN R OD1 1 
ATOM   7429 N ND2 . ASN E 5 121 ? 109.937 94.935  89.193  1.00 98.13  ?  121 ASN R ND2 1 
ATOM   7430 N N   . MET E 5 122 ? 113.558 98.976  88.427  1.00 97.30  ?  122 MET R N   1 
ATOM   7431 C CA  . MET E 5 122 ? 114.791 99.710  88.696  1.00 97.30  ?  122 MET R CA  1 
ATOM   7432 C C   . MET E 5 122 ? 114.534 101.213 88.722  1.00 97.30  ?  122 MET R C   1 
ATOM   7433 O O   . MET E 5 122 ? 114.955 101.915 89.652  1.00 97.30  ?  122 MET R O   1 
ATOM   7434 C CB  . MET E 5 122 ? 115.844 99.362  87.644  1.00 97.30  ?  122 MET R CB  1 
ATOM   7435 C CG  . MET E 5 122 ? 117.202 100.005 87.884  1.00 97.30  ?  122 MET R CG  1 
ATOM   7436 S SD  . MET E 5 122 ? 118.382 99.678  86.559  1.00 97.30  ?  122 MET R SD  1 
ATOM   7437 C CE  . MET E 5 122 ? 118.512 97.894  86.643  1.00 97.30  ?  122 MET R CE  1 
ATOM   7438 N N   . TYR E 5 123 ? 113.837 101.727 87.708  1.00 97.47  ?  123 TYR R N   1 
ATOM   7439 C CA  . TYR E 5 123 ? 113.544 103.153 87.651  1.00 97.47  ?  123 TYR R CA  1 
ATOM   7440 C C   . TYR E 5 123 ? 112.580 103.604 88.741  1.00 97.47  ?  123 TYR R C   1 
ATOM   7441 O O   . TYR E 5 123 ? 112.740 104.712 89.265  1.00 97.47  ?  123 TYR R O   1 
ATOM   7442 C CB  . TYR E 5 123 ? 112.981 103.512 86.275  1.00 97.47  ?  123 TYR R CB  1 
ATOM   7443 C CG  . TYR E 5 123 ? 113.941 103.246 85.136  1.00 97.47  ?  123 TYR R CG  1 
ATOM   7444 C CD1 . TYR E 5 123 ? 115.314 103.379 85.310  1.00 97.47  ?  123 TYR R CD1 1 
ATOM   7445 C CD2 . TYR E 5 123 ? 113.475 102.857 83.889  1.00 97.47  ?  123 TYR R CD2 1 
ATOM   7446 C CE1 . TYR E 5 123 ? 116.192 103.137 84.274  1.00 97.47  ?  123 TYR R CE1 1 
ATOM   7447 C CE2 . TYR E 5 123 ? 114.346 102.611 82.847  1.00 97.47  ?  123 TYR R CE2 1 
ATOM   7448 C CZ  . TYR E 5 123 ? 115.703 102.752 83.045  1.00 97.47  ?  123 TYR R CZ  1 
ATOM   7449 O OH  . TYR E 5 123 ? 116.574 102.508 82.008  1.00 97.47  ?  123 TYR R OH  1 
ATOM   7450 N N   . SER E 5 124 ? 111.599 102.777 89.112  1.00 97.80  ?  124 SER R N   1 
ATOM   7451 C CA  . SER E 5 124 ? 110.734 103.123 90.233  1.00 97.80  ?  124 SER R CA  1 
ATOM   7452 C C   . SER E 5 124 ? 111.519 103.182 91.538  1.00 97.80  ?  124 SER R C   1 
ATOM   7453 O O   . SER E 5 124 ? 111.267 104.052 92.378  1.00 97.80  ?  124 SER R O   1 
ATOM   7454 C CB  . SER E 5 124 ? 109.592 102.114 90.341  1.00 97.80  ?  124 SER R CB  1 
ATOM   7455 O OG  . SER E 5 124 ? 108.668 102.495 91.344  1.00 97.80  ?  124 SER R OG  1 
ATOM   7456 N N   . SER E 5 125 ? 112.476 102.271 91.719  1.00 97.67  ?  125 SER R N   1 
ATOM   7457 C CA  . SER E 5 125 ? 113.332 102.310 92.900  1.00 97.67  ?  125 SER R CA  1 
ATOM   7458 C C   . SER E 5 125 ? 114.167 103.583 92.924  1.00 97.67  ?  125 SER R C   1 
ATOM   7459 O O   . SER E 5 125 ? 114.323 104.220 93.972  1.00 97.67  ?  125 SER R O   1 
ATOM   7460 C CB  . SER E 5 125 ? 114.232 101.075 92.928  1.00 97.67  ?  125 SER R CB  1 
ATOM   7461 O OG  . SER E 5 125 ? 115.219 101.181 93.938  1.00 97.67  ?  125 SER R OG  1 
ATOM   7462 N N   . ILE E 5 126 ? 114.723 103.966 91.772  1.00 97.79  ?  126 ILE R N   1 
ATOM   7463 C CA  . ILE E 5 126 ? 115.502 105.202 91.703  1.00 97.79  ?  126 ILE R CA  1 
ATOM   7464 C C   . ILE E 5 126 ? 114.627 106.398 92.066  1.00 97.79  ?  126 ILE R C   1 
ATOM   7465 O O   . ILE E 5 126 ? 115.031 107.282 92.835  1.00 97.79  ?  126 ILE R O   1 
ATOM   7466 C CB  . ILE E 5 126 ? 116.130 105.363 90.307  1.00 97.79  ?  126 ILE R CB  1 
ATOM   7467 C CG1 . ILE E 5 126 ? 117.162 104.259 90.062  1.00 97.79  ?  126 ILE R CG1 1 
ATOM   7468 C CG2 . ILE E 5 126 ? 116.771 106.740 90.167  1.00 97.79  ?  126 ILE R CG2 1 
ATOM   7469 C CD1 . ILE E 5 126 ? 117.691 104.215 88.642  1.00 97.79  ?  126 ILE R CD1 1 
ATOM   7470 N N   . TYR E 5 127 ? 113.411 106.442 91.518  1.00 97.86  ?  127 TYR R N   1 
ATOM   7471 C CA  . TYR E 5 127 ? 112.519 107.560 91.807  1.00 97.86  ?  127 TYR R CA  1 
ATOM   7472 C C   . TYR E 5 127 ? 112.105 107.585 93.273  1.00 97.86  ?  127 TYR R C   1 
ATOM   7473 O O   . TYR E 5 127 ? 111.977 108.665 93.857  1.00 97.86  ?  127 TYR R O   1 
ATOM   7474 C CB  . TYR E 5 127 ? 111.287 107.498 90.906  1.00 97.86  ?  127 TYR R CB  1 
ATOM   7475 C CG  . TYR E 5 127 ? 111.351 108.445 89.731  1.00 97.86  ?  127 TYR R CG  1 
ATOM   7476 C CD1 . TYR E 5 127 ? 110.919 109.758 89.851  1.00 97.86  ?  127 TYR R CD1 1 
ATOM   7477 C CD2 . TYR E 5 127 ? 111.845 108.027 88.503  1.00 97.86  ?  127 TYR R CD2 1 
ATOM   7478 C CE1 . TYR E 5 127 ? 110.976 110.629 88.782  1.00 97.86  ?  127 TYR R CE1 1 
ATOM   7479 C CE2 . TYR E 5 127 ? 111.906 108.891 87.427  1.00 97.86  ?  127 TYR R CE2 1 
ATOM   7480 C CZ  . TYR E 5 127 ? 111.470 110.191 87.573  1.00 97.86  ?  127 TYR R CZ  1 
ATOM   7481 O OH  . TYR E 5 127 ? 111.528 111.057 86.506  1.00 97.86  ?  127 TYR R OH  1 
ATOM   7482 N N   . PHE E 5 128 ? 111.905 106.420 93.889  1.00 97.66  ?  128 PHE R N   1 
ATOM   7483 C CA  . PHE E 5 128 ? 111.563 106.388 95.307  1.00 97.66  ?  128 PHE R CA  1 
ATOM   7484 C C   . PHE E 5 128 ? 112.741 106.818 96.173  1.00 97.66  ?  128 PHE R C   1 
ATOM   7485 O O   . PHE E 5 128 ? 112.550 107.476 97.202  1.00 97.66  ?  128 PHE R O   1 
ATOM   7486 C CB  . PHE E 5 128 ? 111.089 104.989 95.704  1.00 97.66  ?  128 PHE R CB  1 
ATOM   7487 C CG  . PHE E 5 128 ? 109.823 104.555 95.016  1.00 97.66  ?  128 PHE R CG  1 
ATOM   7488 C CD1 . PHE E 5 128 ? 108.937 105.486 94.497  1.00 97.66  ?  128 PHE R CD1 1 
ATOM   7489 C CD2 . PHE E 5 128 ? 109.517 103.211 94.894  1.00 97.66  ?  128 PHE R CD2 1 
ATOM   7490 C CE1 . PHE E 5 128 ? 107.776 105.085 93.869  1.00 97.66  ?  128 PHE R CE1 1 
ATOM   7491 C CE2 . PHE E 5 128 ? 108.356 102.804 94.267  1.00 97.66  ?  128 PHE R CE2 1 
ATOM   7492 C CZ  . PHE E 5 128 ? 107.485 103.744 93.754  1.00 97.66  ?  128 PHE R CZ  1 
ATOM   7493 N N   . LEU E 5 129 ? 113.963 106.455 95.779  1.00 96.59  ?  129 LEU R N   1 
ATOM   7494 C CA  . LEU E 5 129 ? 115.137 106.948 96.491  1.00 96.59  ?  129 LEU R CA  1 
ATOM   7495 C C   . LEU E 5 129 ? 115.245 108.462 96.392  1.00 96.59  ?  129 LEU R C   1 
ATOM   7496 O O   . LEU E 5 129 ? 115.613 109.124 97.369  1.00 96.59  ?  129 LEU R O   1 
ATOM   7497 C CB  . LEU E 5 129 ? 116.403 106.288 95.945  1.00 96.59  ?  129 LEU R CB  1 
ATOM   7498 C CG  . LEU E 5 129 ? 116.552 104.787 96.204  1.00 96.59  ?  129 LEU R CG  1 
ATOM   7499 C CD1 . LEU E 5 129 ? 117.778 104.242 95.489  1.00 96.59  ?  129 LEU R CD1 1 
ATOM   7500 C CD2 . LEU E 5 129 ? 116.633 104.500 97.697  1.00 96.59  ?  129 LEU R CD2 1 
ATOM   7501 N N   . THR E 5 130 ? 114.932 109.029 95.225  1.00 96.88  ?  130 THR R N   1 
ATOM   7502 C CA  . THR E 5 130 ? 114.933 110.484 95.092  1.00 96.88  ?  130 THR R CA  1 
ATOM   7503 C C   . THR E 5 130 ? 113.826 111.120 95.929  1.00 96.88  ?  130 THR R C   1 
ATOM   7504 O O   . THR E 5 130 ? 114.022 112.193 96.517  1.00 96.88  ?  130 THR R O   1 
ATOM   7505 C CB  . THR E 5 130 ? 114.778 110.878 93.622  1.00 96.88  ?  130 THR R CB  1 
ATOM   7506 O OG1 . THR E 5 130 ? 115.831 110.284 92.851  1.00 96.88  ?  130 THR R OG1 1 
ATOM   7507 C CG2 . THR E 5 130 ? 114.830 112.392 93.464  1.00 96.88  ?  130 THR R CG2 1 
ATOM   7508 N N   . VAL E 5 131 ? 112.658 110.477 95.983  1.00 95.74  ?  131 VAL R N   1 
ATOM   7509 C CA  . VAL E 5 131 ? 111.553 110.995 96.784  1.00 95.74  ?  131 VAL R CA  1 
ATOM   7510 C C   . VAL E 5 131 ? 111.932 111.020 98.258  1.00 95.74  ?  131 VAL R C   1 
ATOM   7511 O O   . VAL E 5 131 ? 111.711 112.017 98.953  1.00 95.74  ?  131 VAL R O   1 
ATOM   7512 C CB  . VAL E 5 131 ? 110.280 110.162 96.540  1.00 95.74  ?  131 VAL R CB  1 
ATOM   7513 C CG1 . VAL E 5 131 ? 109.218 110.494 97.577  1.00 95.74  ?  131 VAL R CG1 1 
ATOM   7514 C CG2 . VAL E 5 131 ? 109.746 110.409 95.138  1.00 95.74  ?  131 VAL R CG2 1 
ATOM   7515 N N   . LEU E 5 132 ? 112.496 109.920 98.762  1.00 94.44  ?  132 LEU R N   1 
ATOM   7516 C CA  . LEU E 5 132 ? 112.976 109.895 100.139 1.00 94.44  ?  132 LEU R CA  1 
ATOM   7517 C C   . LEU E 5 132 ? 114.036 110.957 100.392 1.00 94.44  ?  132 LEU R C   1 
ATOM   7518 O O   . LEU E 5 132 ? 114.035 111.580 101.462 1.00 94.44  ?  132 LEU R O   1 
ATOM   7519 C CB  . LEU E 5 132 ? 113.545 108.515 100.476 1.00 94.44  ?  132 LEU R CB  1 
ATOM   7520 C CG  . LEU E 5 132 ? 112.550 107.355 100.511 1.00 94.44  ?  132 LEU R CG  1 
ATOM   7521 C CD1 . LEU E 5 132 ? 113.283 106.031 100.663 1.00 94.44  ?  132 LEU R CD1 1 
ATOM   7522 C CD2 . LEU E 5 132 ? 111.550 107.544 101.637 1.00 94.44  ?  132 LEU R CD2 1 
ATOM   7523 N N   . SER E 5 133 ? 114.939 111.169 99.433  1.00 94.11  ?  133 SER R N   1 
ATOM   7524 C CA  . SER E 5 133 ? 115.961 112.197 99.586  1.00 94.11  ?  133 SER R CA  1 
ATOM   7525 C C   . SER E 5 133 ? 115.330 113.570 99.761  1.00 94.11  ?  133 SER R C   1 
ATOM   7526 O O   . SER E 5 133 ? 115.647 114.293 100.712 1.00 94.11  ?  133 SER R O   1 
ATOM   7527 C CB  . SER E 5 133 ? 116.890 112.193 98.375  1.00 94.11  ?  133 SER R CB  1 
ATOM   7528 O OG  . SER E 5 133 ? 116.174 112.511 97.194  1.00 94.11  ?  133 SER R OG  1 
ATOM   7529 N N   . VAL E 5 134 ? 114.440 113.953 98.843  1.00 93.64  ?  134 VAL R N   1 
ATOM   7530 C CA  . VAL E 5 134 ? 113.814 115.269 98.944  1.00 93.64  ?  134 VAL R CA  1 
ATOM   7531 C C   . VAL E 5 134 ? 112.978 115.367 100.212 1.00 93.64  ?  134 VAL R C   1 
ATOM   7532 O O   . VAL E 5 134 ? 112.896 116.436 100.831 1.00 93.64  ?  134 VAL R O   1 
ATOM   7533 C CB  . VAL E 5 134 ? 112.975 115.572 97.685  1.00 93.64  ?  134 VAL R CB  1 
ATOM   7534 C CG1 . VAL E 5 134 ? 111.869 114.546 97.507  1.00 93.64  ?  134 VAL R CG1 1 
ATOM   7535 C CG2 . VAL E 5 134 ? 112.399 116.979 97.760  1.00 93.64  ?  134 VAL R CG2 1 
ATOM   7536 N N   . VAL E 5 135 ? 112.365 114.260 100.636 1.00 91.26  ?  135 VAL R N   1 
ATOM   7537 C CA  . VAL E 5 135 ? 111.542 114.276 101.842 1.00 91.26  ?  135 VAL R CA  1 
ATOM   7538 C C   . VAL E 5 135 ? 112.396 114.592 103.063 1.00 91.26  ?  135 VAL R C   1 
ATOM   7539 O O   . VAL E 5 135 ? 112.106 115.527 103.820 1.00 91.26  ?  135 VAL R O   1 
ATOM   7540 C CB  . VAL E 5 135 ? 110.804 112.934 102.001 1.00 91.26  ?  135 VAL R CB  1 
ATOM   7541 C CG1 . VAL E 5 135 ? 110.261 112.784 103.413 1.00 91.26  ?  135 VAL R CG1 1 
ATOM   7542 C CG2 . VAL E 5 135 ? 109.681 112.826 100.982 1.00 91.26  ?  135 VAL R CG2 1 
ATOM   7543 N N   . ARG E 5 136 ? 113.454 113.813 103.278 1.00 90.23  ?  136 ARG R N   1 
ATOM   7544 C CA  . ARG E 5 136 ? 114.324 114.020 104.428 1.00 90.23  ?  136 ARG R CA  1 
ATOM   7545 C C   . ARG E 5 136 ? 115.234 115.231 104.265 1.00 90.23  ?  136 ARG R C   1 
ATOM   7546 O O   . ARG E 5 136 ? 115.945 115.587 105.210 1.00 90.23  ?  136 ARG R O   1 
ATOM   7547 C CB  . ARG E 5 136 ? 115.161 112.763 104.696 1.00 90.23  ?  136 ARG R CB  1 
ATOM   7548 C CG  . ARG E 5 136 ? 116.190 112.423 103.632 1.00 90.23  ?  136 ARG R CG  1 
ATOM   7549 C CD  . ARG E 5 136 ? 116.590 110.956 103.740 1.00 90.23  ?  136 ARG R CD  1 
ATOM   7550 N NE  . ARG E 5 136 ? 117.918 110.678 103.200 1.00 90.23  ?  136 ARG R NE  1 
ATOM   7551 C CZ  . ARG E 5 136 ? 118.489 109.476 103.209 1.00 90.23  ?  136 ARG R CZ  1 
ATOM   7552 N NH1 . ARG E 5 136 ? 117.847 108.436 103.726 1.00 90.23  1  136 ARG R NH1 1 
ATOM   7553 N NH2 . ARG E 5 136 ? 119.702 109.309 102.700 1.00 90.23  ?  136 ARG R NH2 1 
ATOM   7554 N N   . PHE E 5 137 ? 115.231 115.866 103.092 1.00 89.02  ?  137 PHE R N   1 
ATOM   7555 C CA  . PHE E 5 137 ? 115.883 117.161 102.935 1.00 89.02  ?  137 PHE R CA  1 
ATOM   7556 C C   . PHE E 5 137 ? 114.963 118.288 103.391 1.00 89.02  ?  137 PHE R C   1 
ATOM   7557 O O   . PHE E 5 137 ? 115.377 119.181 104.138 1.00 89.02  ?  137 PHE R O   1 
ATOM   7558 C CB  . PHE E 5 137 ? 116.300 117.359 101.475 1.00 89.02  ?  137 PHE R CB  1 
ATOM   7559 C CG  . PHE E 5 137 ? 116.339 118.797 101.043 1.00 89.02  ?  137 PHE R CG  1 
ATOM   7560 C CD1 . PHE E 5 137 ? 117.420 119.602 101.359 1.00 89.02  ?  137 PHE R CD1 1 
ATOM   7561 C CD2 . PHE E 5 137 ? 115.296 119.342 100.313 1.00 89.02  ?  137 PHE R CD2 1 
ATOM   7562 C CE1 . PHE E 5 137 ? 117.456 120.924 100.960 1.00 89.02  ?  137 PHE R CE1 1 
ATOM   7563 C CE2 . PHE E 5 137 ? 115.327 120.663 99.911  1.00 89.02  ?  137 PHE R CE2 1 
ATOM   7564 C CZ  . PHE E 5 137 ? 116.408 121.455 100.235 1.00 89.02  ?  137 PHE R CZ  1 
ATOM   7565 N N   . LEU E 5 138 ? 113.707 118.265 102.936 1.00 87.83  ?  138 LEU R N   1 
ATOM   7566 C CA  . LEU E 5 138 ? 112.741 119.258 103.390 1.00 87.83  ?  138 LEU R CA  1 
ATOM   7567 C C   . LEU E 5 138 ? 112.482 119.139 104.885 1.00 87.83  ?  138 LEU R C   1 
ATOM   7568 O O   . LEU E 5 138 ? 112.231 120.147 105.554 1.00 87.83  ?  138 LEU R O   1 
ATOM   7569 C CB  . LEU E 5 138 ? 111.431 119.110 102.614 1.00 87.83  ?  138 LEU R CB  1 
ATOM   7570 C CG  . LEU E 5 138 ? 111.505 119.360 101.106 1.00 87.83  ?  138 LEU R CG  1 
ATOM   7571 C CD1 . LEU E 5 138 ? 110.171 119.037 100.451 1.00 87.83  ?  138 LEU R CD1 1 
ATOM   7572 C CD2 . LEU E 5 138 ? 111.913 120.795 100.809 1.00 87.83  ?  138 LEU R CD2 1 
ATOM   7573 N N   . ALA E 5 139 ? 112.538 117.920 105.427 1.00 83.97  ?  139 ALA R N   1 
ATOM   7574 C CA  . ALA E 5 139 ? 112.308 117.742 106.856 1.00 83.97  ?  139 ALA R CA  1 
ATOM   7575 C C   . ALA E 5 139 ? 113.439 118.345 107.679 1.00 83.97  ?  139 ALA R C   1 
ATOM   7576 O O   . ALA E 5 139 ? 113.214 118.825 108.796 1.00 83.97  ?  139 ALA R O   1 
ATOM   7577 C CB  . ALA E 5 139 ? 112.146 116.257 107.178 1.00 83.97  ?  139 ALA R CB  1 
ATOM   7578 N N   . MET E 5 140 ? 114.660 118.332 107.146 1.00 82.86  ?  140 MET R N   1 
ATOM   7579 C CA  . MET E 5 140 ? 115.831 118.773 107.894 1.00 82.86  ?  140 MET R CA  1 
ATOM   7580 C C   . MET E 5 140 ? 116.100 120.265 107.721 1.00 82.86  ?  140 MET R C   1 
ATOM   7581 O O   . MET E 5 140 ? 116.311 120.977 108.707 1.00 82.86  ?  140 MET R O   1 
ATOM   7582 C CB  . MET E 5 140 ? 117.057 117.964 107.459 1.00 82.86  ?  140 MET R CB  1 
ATOM   7583 C CG  . MET E 5 140 ? 117.809 117.310 108.607 1.00 82.86  ?  140 MET R CG  1 
ATOM   7584 S SD  . MET E 5 140 ? 116.791 116.167 109.564 1.00 82.86  ?  140 MET R SD  1 
ATOM   7585 C CE  . MET E 5 140 ? 116.343 114.967 108.312 1.00 82.86  ?  140 MET R CE  1 
ATOM   7586 N N   . VAL E 5 141 ? 116.095 120.753 106.480 1.00 81.66  ?  141 VAL R N   1 
ATOM   7587 C CA  . VAL E 5 141 ? 116.439 122.151 106.243 1.00 81.66  ?  141 VAL R CA  1 
ATOM   7588 C C   . VAL E 5 141 ? 115.342 123.083 106.746 1.00 81.66  ?  141 VAL R C   1 
ATOM   7589 O O   . VAL E 5 141 ? 115.596 124.269 106.988 1.00 81.66  ?  141 VAL R O   1 
ATOM   7590 C CB  . VAL E 5 141 ? 116.722 122.386 104.749 1.00 81.66  ?  141 VAL R CB  1 
ATOM   7591 C CG1 . VAL E 5 141 ? 117.781 121.414 104.250 1.00 81.66  ?  141 VAL R CG1 1 
ATOM   7592 C CG2 . VAL E 5 141 ? 115.441 122.264 103.938 1.00 81.66  ?  141 VAL R CG2 1 
ATOM   7593 N N   . HIS E 5 142 ? 114.121 122.580 106.915 1.00 77.50  ?  142 HIS R N   1 
ATOM   7594 C CA  . HIS E 5 142 ? 112.983 123.376 107.374 1.00 77.50  ?  142 HIS R CA  1 
ATOM   7595 C C   . HIS E 5 142 ? 112.279 122.629 108.500 1.00 77.50  ?  142 HIS R C   1 
ATOM   7596 O O   . HIS E 5 142 ? 111.149 122.153 108.339 1.00 77.50  ?  142 HIS R O   1 
ATOM   7597 C CB  . HIS E 5 142 ? 112.021 123.667 106.221 1.00 77.50  ?  142 HIS R CB  1 
ATOM   7598 C CG  . HIS E 5 142 ? 112.641 124.432 105.094 1.00 77.50  ?  142 HIS R CG  1 
ATOM   7599 N ND1 . HIS E 5 142 ? 113.724 125.268 105.267 1.00 77.50  ?  142 HIS R ND1 1 
ATOM   7600 C CD2 . HIS E 5 142 ? 112.331 124.486 103.777 1.00 77.50  ?  142 HIS R CD2 1 
ATOM   7601 C CE1 . HIS E 5 142 ? 114.052 125.805 104.106 1.00 77.50  ?  142 HIS R CE1 1 
ATOM   7602 N NE2 . HIS E 5 142 ? 113.223 125.347 103.186 1.00 77.50  ?  142 HIS R NE2 1 
ATOM   7603 N N   . PRO E 5 143 ? 112.924 122.511 109.664 1.00 71.55  ?  143 PRO R N   1 
ATOM   7604 C CA  . PRO E 5 143 ? 112.300 121.785 110.778 1.00 71.55  ?  143 PRO R CA  1 
ATOM   7605 C C   . PRO E 5 143 ? 111.098 122.512 111.363 1.00 71.55  ?  143 PRO R C   1 
ATOM   7606 O O   . PRO E 5 143 ? 110.031 121.915 111.536 1.00 71.55  ?  143 PRO R O   1 
ATOM   7607 C CB  . PRO E 5 143 ? 113.439 121.656 111.800 1.00 71.55  ?  143 PRO R CB  1 
ATOM   7608 C CG  . PRO E 5 143 ? 114.467 122.680 111.418 1.00 71.55  ?  143 PRO R CG  1 
ATOM   7609 C CD  . PRO E 5 143 ? 114.107 123.276 110.088 1.00 71.55  ?  143 PRO R CD  1 
ATOM   7610 N N   . PHE E 5 144 ? 111.259 123.800 111.674 1.00 67.45  ?  144 PHE R N   1 
ATOM   7611 C CA  . PHE E 5 144 ? 110.173 124.554 112.294 1.00 67.45  ?  144 PHE R CA  1 
ATOM   7612 C C   . PHE E 5 144 ? 109.087 124.906 111.285 1.00 67.45  ?  144 PHE R C   1 
ATOM   7613 O O   . PHE E 5 144 ? 107.943 124.453 111.402 1.00 67.45  ?  144 PHE R O   1 
ATOM   7614 C CB  . PHE E 5 144 ? 110.723 125.829 112.941 1.00 67.45  ?  144 PHE R CB  1 
ATOM   7615 C CG  . PHE E 5 144 ? 111.388 125.611 114.276 1.00 67.45  ?  144 PHE R CG  1 
ATOM   7616 C CD1 . PHE E 5 144 ? 111.563 124.337 114.796 1.00 67.45  ?  144 PHE R CD1 1 
ATOM   7617 C CD2 . PHE E 5 144 ? 111.826 126.694 115.017 1.00 67.45  ?  144 PHE R CD2 1 
ATOM   7618 C CE1 . PHE E 5 144 ? 112.167 124.153 116.023 1.00 67.45  ?  144 PHE R CE1 1 
ATOM   7619 C CE2 . PHE E 5 144 ? 112.431 126.514 116.243 1.00 67.45  ?  144 PHE R CE2 1 
ATOM   7620 C CZ  . PHE E 5 144 ? 112.601 125.244 116.746 1.00 67.45  ?  144 PHE R CZ  1 
ATOM   7621 N N   . ARG E 5 145 ? 109.427 125.716 110.290 1.00 61.02  ?  145 ARG R N   1 
ATOM   7622 C CA  . ARG E 5 145 ? 108.447 126.241 109.354 1.00 61.02  ?  145 ARG R CA  1 
ATOM   7623 C C   . ARG E 5 145 ? 108.379 125.377 108.098 1.00 61.02  ?  145 ARG R C   1 
ATOM   7624 O O   . ARG E 5 145 ? 109.242 124.534 107.842 1.00 61.02  ?  145 ARG R O   1 
ATOM   7625 C CB  . ARG E 5 145 ? 108.789 127.685 108.980 1.00 61.02  ?  145 ARG R CB  1 
ATOM   7626 C CG  . ARG E 5 145 ? 109.087 128.581 110.175 1.00 61.02  ?  145 ARG R CG  1 
ATOM   7627 C CD  . ARG E 5 145 ? 109.362 130.014 109.748 1.00 61.02  ?  145 ARG R CD  1 
ATOM   7628 N NE  . ARG E 5 145 ? 108.180 130.654 109.178 1.00 61.02  ?  145 ARG R NE  1 
ATOM   7629 C CZ  . ARG E 5 145 ? 108.158 131.893 108.696 1.00 61.02  ?  145 ARG R CZ  1 
ATOM   7630 N NH1 . ARG E 5 145 ? 109.257 132.636 108.709 1.00 61.02  1  145 ARG R NH1 1 
ATOM   7631 N NH2 . ARG E 5 145 ? 107.034 132.390 108.199 1.00 61.02  ?  145 ARG R NH2 1 
ATOM   7632 N N   . LEU E 5 146 ? 107.325 125.601 107.311 1.00 63.35  ?  146 LEU R N   1 
ATOM   7633 C CA  . LEU E 5 146 ? 107.132 124.886 106.056 1.00 63.35  ?  146 LEU R CA  1 
ATOM   7634 C C   . LEU E 5 146 ? 107.068 123.384 106.299 1.00 63.35  ?  146 LEU R C   1 
ATOM   7635 O O   . LEU E 5 146 ? 107.927 122.637 105.818 1.00 63.35  ?  146 LEU R O   1 
ATOM   7636 C CB  . LEU E 5 146 ? 108.256 125.218 105.070 1.00 63.35  ?  146 LEU R CB  1 
ATOM   7637 C CG  . LEU E 5 146 ? 108.500 126.709 104.815 1.00 63.35  ?  146 LEU R CG  1 
ATOM   7638 C CD1 . LEU E 5 146 ? 109.678 126.912 103.875 1.00 63.35  ?  146 LEU R CD1 1 
ATOM   7639 C CD2 . LEU E 5 146 ? 107.253 127.392 104.262 1.00 63.35  ?  146 LEU R CD2 1 
ATOM   7640 N N   . LEU E 5 147 ? 106.059 122.928 107.042 1.00 61.14  ?  147 LEU R N   1 
ATOM   7641 C CA  . LEU E 5 147 ? 105.903 121.501 107.328 1.00 61.14  ?  147 LEU R CA  1 
ATOM   7642 C C   . LEU E 5 147 ? 105.138 120.830 106.188 1.00 61.14  ?  147 LEU R C   1 
ATOM   7643 O O   . LEU E 5 147 ? 104.139 120.135 106.379 1.00 61.14  ?  147 LEU R O   1 
ATOM   7644 C CB  . LEU E 5 147 ? 105.201 121.289 108.664 1.00 61.14  ?  147 LEU R CB  1 
ATOM   7645 C CG  . LEU E 5 147 ? 105.839 121.898 109.913 1.00 61.14  ?  147 LEU R CG  1 
ATOM   7646 C CD1 . LEU E 5 147 ? 105.516 123.382 110.034 1.00 61.14  ?  147 LEU R CD1 1 
ATOM   7647 C CD2 . LEU E 5 147 ? 105.377 121.140 111.147 1.00 61.14  ?  147 LEU R CD2 1 
ATOM   7648 N N   . HIS E 5 148 ? 105.639 121.051 104.974 1.00 59.83  ?  148 HIS R N   1 
ATOM   7649 C CA  . HIS E 5 148 ? 105.091 120.383 103.800 1.00 59.83  ?  148 HIS R CA  1 
ATOM   7650 C C   . HIS E 5 148 ? 105.836 119.076 103.563 1.00 59.83  ?  148 HIS R C   1 
ATOM   7651 O O   . HIS E 5 148 ? 106.358 118.843 102.467 1.00 59.83  ?  148 HIS R O   1 
ATOM   7652 C CB  . HIS E 5 148 ? 105.180 121.289 102.566 1.00 59.83  ?  148 HIS R CB  1 
ATOM   7653 C CG  . HIS E 5 148 ? 106.555 121.819 102.303 1.00 59.83  ?  148 HIS R CG  1 
ATOM   7654 N ND1 . HIS E 5 148 ? 106.799 122.875 101.453 1.00 59.83  ?  148 HIS R ND1 1 
ATOM   7655 C CD2 . HIS E 5 148 ? 107.761 121.440 102.785 1.00 59.83  ?  148 HIS R CD2 1 
ATOM   7656 C CE1 . HIS E 5 148 ? 108.095 123.124 101.422 1.00 59.83  ?  148 HIS R CE1 1 
ATOM   7657 N NE2 . HIS E 5 148 ? 108.702 122.267 102.222 1.00 59.83  ?  148 HIS R NE2 1 
ATOM   7658 N N   . VAL E 5 149 ? 105.907 118.229 104.591 1.00 59.82  ?  149 VAL R N   1 
ATOM   7659 C CA  . VAL E 5 149 ? 106.578 116.937 104.495 1.00 59.82  ?  149 VAL R CA  1 
ATOM   7660 C C   . VAL E 5 149 ? 105.641 115.845 104.996 1.00 59.82  ?  149 VAL R C   1 
ATOM   7661 O O   . VAL E 5 149 ? 105.520 114.782 104.378 1.00 59.82  ?  149 VAL R O   1 
ATOM   7662 C CB  . VAL E 5 149 ? 107.906 116.931 105.277 1.00 59.82  ?  149 VAL R CB  1 
ATOM   7663 C CG1 . VAL E 5 149 ? 107.672 117.211 106.761 1.00 59.82  ?  149 VAL R CG1 1 
ATOM   7664 C CG2 . VAL E 5 149 ? 108.626 115.603 105.081 1.00 59.82  ?  149 VAL R CG2 1 
ATOM   7665 N N   . THR E 5 150 ? 104.975 116.100 106.119 1.00 71.36  ?  150 THR R N   1 
ATOM   7666 C CA  . THR E 5 150 ? 104.111 115.106 106.745 1.00 71.36  ?  150 THR R CA  1 
ATOM   7667 C C   . THR E 5 150 ? 102.852 114.916 105.907 1.00 71.36  ?  150 THR R C   1 
ATOM   7668 O O   . THR E 5 150 ? 102.223 115.894 105.489 1.00 71.36  ?  150 THR R O   1 
ATOM   7669 C CB  . THR E 5 150 ? 103.746 115.538 108.164 1.00 71.36  ?  150 THR R CB  1 
ATOM   7670 O OG1 . THR E 5 150 ? 103.087 116.810 108.125 1.00 71.36  ?  150 THR R OG1 1 
ATOM   7671 C CG2 . THR E 5 150 ? 104.995 115.642 109.031 1.00 71.36  ?  150 THR R CG2 1 
ATOM   7672 N N   . SER E 5 151 ? 102.487 113.660 105.662 1.00 84.90  ?  151 SER R N   1 
ATOM   7673 C CA  . SER E 5 151 ? 101.280 113.335 104.913 1.00 84.90  ?  151 SER R CA  1 
ATOM   7674 C C   . SER E 5 151 ? 100.994 111.851 105.082 1.00 84.90  ?  151 SER R C   1 
ATOM   7675 O O   . SER E 5 151 ? 101.860 111.078 105.503 1.00 84.90  ?  151 SER R O   1 
ATOM   7676 C CB  . SER E 5 151 ? 101.418 113.689 103.428 1.00 84.90  ?  151 SER R CB  1 
ATOM   7677 O OG  . SER E 5 151 ? 101.623 115.080 103.247 1.00 84.90  ?  151 SER R OG  1 
ATOM   7678 N N   . ILE E 5 152 ? 99.762  111.465 104.752 1.00 89.54  ?  152 ILE R N   1 
ATOM   7679 C CA  . ILE E 5 152 ? 99.340  110.071 104.833 1.00 89.54  ?  152 ILE R CA  1 
ATOM   7680 C C   . ILE E 5 152 ? 98.844  109.615 103.467 1.00 89.54  ?  152 ILE R C   1 
ATOM   7681 O O   . ILE E 5 152 ? 99.231  108.547 102.979 1.00 89.54  ?  152 ILE R O   1 
ATOM   7682 C CB  . ILE E 5 152 ? 98.263  109.874 105.919 1.00 89.54  ?  152 ILE R CB  1 
ATOM   7683 C CG1 . ILE E 5 152 ? 97.853  108.400 106.021 1.00 89.54  ?  152 ILE R CG1 1 
ATOM   7684 C CG2 . ILE E 5 152 ? 97.038  110.742 105.643 1.00 89.54  ?  152 ILE R CG2 1 
ATOM   7685 C CD1 . ILE E 5 152 ? 98.997  107.463 106.350 1.00 89.54  ?  152 ILE R CD1 1 
ATOM   7686 N N   . ARG E 5 153 ? 97.987  110.423 102.838 1.00 91.38  ?  153 ARG R N   1 
ATOM   7687 C CA  . ARG E 5 153 ? 97.412  110.049 101.550 1.00 91.38  ?  153 ARG R CA  1 
ATOM   7688 C C   . ARG E 5 153 ? 98.243  110.581 100.388 1.00 91.38  ?  153 ARG R C   1 
ATOM   7689 O O   . ARG E 5 153 ? 98.343  109.926 99.343  1.00 91.38  ?  153 ARG R O   1 
ATOM   7690 C CB  . ARG E 5 153 ? 95.974  110.563 101.454 1.00 91.38  ?  153 ARG R CB  1 
ATOM   7691 C CG  . ARG E 5 153 ? 95.246  110.180 100.172 1.00 91.38  ?  153 ARG R CG  1 
ATOM   7692 C CD  . ARG E 5 153 ? 95.138  108.672 100.015 1.00 91.38  ?  153 ARG R CD  1 
ATOM   7693 N NE  . ARG E 5 153 ? 94.375  108.295 98.829  1.00 91.38  ?  153 ARG R NE  1 
ATOM   7694 C CZ  . ARG E 5 153 ? 94.150  107.041 98.450  1.00 91.38  ?  153 ARG R CZ  1 
ATOM   7695 N NH1 . ARG E 5 153 ? 94.629  106.030 99.164  1.00 91.38  1  153 ARG R NH1 1 
ATOM   7696 N NH2 . ARG E 5 153 ? 93.444  106.796 97.355  1.00 91.38  ?  153 ARG R NH2 1 
ATOM   7697 N N   . SER E 5 154 ? 98.834  111.769 100.545 1.00 91.36  ?  154 SER R N   1 
ATOM   7698 C CA  . SER E 5 154 ? 99.645  112.335 99.472  1.00 91.36  ?  154 SER R CA  1 
ATOM   7699 C C   . SER E 5 154 ? 100.801 111.415 99.104  1.00 91.36  ?  154 SER R C   1 
ATOM   7700 O O   . SER E 5 154 ? 101.192 111.348 97.933  1.00 91.36  ?  154 SER R O   1 
ATOM   7701 C CB  . SER E 5 154 ? 100.171 113.711 99.880  1.00 91.36  ?  154 SER R CB  1 
ATOM   7702 O OG  . SER E 5 154 ? 99.106  114.596 100.177 1.00 91.36  ?  154 SER R OG  1 
ATOM   7703 N N   . ALA E 5 155 ? 101.353 110.694 100.081 1.00 94.08  ?  155 ALA R N   1 
ATOM   7704 C CA  . ALA E 5 155 ? 102.435 109.760 99.789  1.00 94.08  ?  155 ALA R CA  1 
ATOM   7705 C C   . ALA E 5 155 ? 101.963 108.660 98.847  1.00 94.08  ?  155 ALA R C   1 
ATOM   7706 O O   . ALA E 5 155 ? 102.620 108.362 97.842  1.00 94.08  ?  155 ALA R O   1 
ATOM   7707 C CB  . ALA E 5 155 ? 102.974 109.164 101.089 1.00 94.08  ?  155 ALA R CB  1 
ATOM   7708 N N   . TRP E 5 156 ? 100.823 108.040 99.160  1.00 95.70  ?  156 TRP R N   1 
ATOM   7709 C CA  . TRP E 5 156 ? 100.286 107.002 98.287  1.00 95.70  ?  156 TRP R CA  1 
ATOM   7710 C C   . TRP E 5 156 ? 99.936  107.566 96.916  1.00 95.70  ?  156 TRP R C   1 
ATOM   7711 O O   . TRP E 5 156 ? 100.150 106.906 95.893  1.00 95.70  ?  156 TRP R O   1 
ATOM   7712 C CB  . TRP E 5 156 ? 99.056  106.356 98.926  1.00 95.70  ?  156 TRP R CB  1 
ATOM   7713 C CG  . TRP E 5 156 ? 99.370  105.510 100.120 1.00 95.70  ?  156 TRP R CG  1 
ATOM   7714 C CD1 . TRP E 5 156 ? 99.259  105.869 101.431 1.00 95.70  ?  156 TRP R CD1 1 
ATOM   7715 C CD2 . TRP E 5 156 ? 99.846  104.158 100.114 1.00 95.70  ?  156 TRP R CD2 1 
ATOM   7716 N NE1 . TRP E 5 156 ? 99.636  104.826 102.242 1.00 95.70  ?  156 TRP R NE1 1 
ATOM   7717 C CE2 . TRP E 5 156 ? 100.001 103.764 101.458 1.00 95.70  ?  156 TRP R CE2 1 
ATOM   7718 C CE3 . TRP E 5 156 ? 100.157 103.243 99.103  1.00 95.70  ?  156 TRP R CE3 1 
ATOM   7719 C CZ2 . TRP E 5 156 ? 100.453 102.496 101.816 1.00 95.70  ?  156 TRP R CZ2 1 
ATOM   7720 C CZ3 . TRP E 5 156 ? 100.605 101.985 99.461  1.00 95.70  ?  156 TRP R CZ3 1 
ATOM   7721 C CH2 . TRP E 5 156 ? 100.749 101.623 100.806 1.00 95.70  ?  156 TRP R CH2 1 
ATOM   7722 N N   . ILE E 5 157 ? 99.393  108.784 96.875  1.00 95.73  ?  157 ILE R N   1 
ATOM   7723 C CA  . ILE E 5 157 ? 99.046  109.395 95.594  1.00 95.73  ?  157 ILE R CA  1 
ATOM   7724 C C   . ILE E 5 157 ? 100.294 109.564 94.736  1.00 95.73  ?  157 ILE R C   1 
ATOM   7725 O O   . ILE E 5 157 ? 100.304 109.221 93.547  1.00 95.73  ?  157 ILE R O   1 
ATOM   7726 C CB  . ILE E 5 157 ? 98.328  110.739 95.816  1.00 95.73  ?  157 ILE R CB  1 
ATOM   7727 C CG1 . ILE E 5 157 ? 96.948  110.502 96.438  1.00 95.73  ?  157 ILE R CG1 1 
ATOM   7728 C CG2 . ILE E 5 157 ? 98.208  111.500 94.499  1.00 95.73  ?  157 ILE R CG2 1 
ATOM   7729 C CD1 . ILE E 5 157 ? 96.247  111.769 96.895  1.00 95.73  ?  157 ILE R CD1 1 
ATOM   7730 N N   . LEU E 5 158 ? 101.366 110.097 95.327  1.00 95.78  ?  158 LEU R N   1 
ATOM   7731 C CA  . LEU E 5 158 ? 102.597 110.304 94.573  1.00 95.78  ?  158 LEU R CA  1 
ATOM   7732 C C   . LEU E 5 158 ? 103.199 108.978 94.127  1.00 95.78  ?  158 LEU R C   1 
ATOM   7733 O O   . LEU E 5 158 ? 103.679 108.854 92.993  1.00 95.78  ?  158 LEU R O   1 
ATOM   7734 C CB  . LEU E 5 158 ? 103.599 111.093 95.417  1.00 95.78  ?  158 LEU R CB  1 
ATOM   7735 C CG  . LEU E 5 158 ? 104.948 111.403 94.763  1.00 95.78  ?  158 LEU R CG  1 
ATOM   7736 C CD1 . LEU E 5 158 ? 104.765 112.232 93.500  1.00 95.78  ?  158 LEU R CD1 1 
ATOM   7737 C CD2 . LEU E 5 158 ? 105.861 112.117 95.746  1.00 95.78  ?  158 LEU R CD2 1 
ATOM   7738 N N   . CYS E 5 159 ? 103.186 107.973 95.006  1.00 97.68  ?  159 CYS R N   1 
ATOM   7739 C CA  . CYS E 5 159 ? 103.721 106.666 94.638  1.00 97.68  ?  159 CYS R CA  1 
ATOM   7740 C C   . CYS E 5 159 ? 102.947 106.072 93.467  1.00 97.68  ?  159 CYS R C   1 
ATOM   7741 O O   . CYS E 5 159 ? 103.539 105.556 92.513  1.00 97.68  ?  159 CYS R O   1 
ATOM   7742 C CB  . CYS E 5 159 ? 103.685 105.726 95.843  1.00 97.68  ?  159 CYS R CB  1 
ATOM   7743 S SG  . CYS E 5 159 ? 104.894 106.121 97.128  1.00 97.68  ?  159 CYS R SG  1 
ATOM   7744 N N   . GLY E 5 160 ? 101.615 106.141 93.522  1.00 98.02  ?  160 GLY R N   1 
ATOM   7745 C CA  . GLY E 5 160 ? 100.814 105.615 92.430  1.00 98.02  ?  160 GLY R CA  1 
ATOM   7746 C C   . GLY E 5 160 ? 101.030 106.374 91.136  1.00 98.02  ?  160 GLY R C   1 
ATOM   7747 O O   . GLY E 5 160 ? 101.081 105.778 90.057  1.00 98.02  ?  160 GLY R O   1 
ATOM   7748 N N   . ILE E 5 161 ? 101.156 107.700 91.222  1.00 97.74  ?  161 ILE R N   1 
ATOM   7749 C CA  . ILE E 5 161 ? 101.422 108.494 90.027  1.00 97.74  ?  161 ILE R CA  1 
ATOM   7750 C C   . ILE E 5 161 ? 102.747 108.079 89.403  1.00 97.74  ?  161 ILE R C   1 
ATOM   7751 O O   . ILE E 5 161 ? 102.843 107.888 88.184  1.00 97.74  ?  161 ILE R O   1 
ATOM   7752 C CB  . ILE E 5 161 ? 101.400 109.996 90.367  1.00 97.74  ?  161 ILE R CB  1 
ATOM   7753 C CG1 . ILE E 5 161 ? 99.974  110.440 90.704  1.00 97.74  ?  161 ILE R CG1 1 
ATOM   7754 C CG2 . ILE E 5 161 ? 101.961 110.812 89.208  1.00 97.74  ?  161 ILE R CG2 1 
ATOM   7755 C CD1 . ILE E 5 161 ? 99.886  111.818 91.328  1.00 97.74  ?  161 ILE R CD1 1 
ATOM   7756 N N   . ILE E 5 162 ? 103.789 107.938 90.224  1.00 97.79  ?  162 ILE R N   1 
ATOM   7757 C CA  . ILE E 5 162 ? 105.093 107.533 89.705  1.00 97.79  ?  162 ILE R CA  1 
ATOM   7758 C C   . ILE E 5 162 ? 104.998 106.156 89.058  1.00 97.79  ?  162 ILE R C   1 
ATOM   7759 O O   . ILE E 5 162 ? 105.512 105.931 87.955  1.00 97.79  ?  162 ILE R O   1 
ATOM   7760 C CB  . ILE E 5 162 ? 106.149 107.562 90.825  1.00 97.79  ?  162 ILE R CB  1 
ATOM   7761 C CG1 . ILE E 5 162 ? 106.362 108.998 91.315  1.00 97.79  ?  162 ILE R CG1 1 
ATOM   7762 C CG2 . ILE E 5 162 ? 107.461 106.965 90.334  1.00 97.79  ?  162 ILE R CG2 1 
ATOM   7763 C CD1 . ILE E 5 162 ? 107.192 109.105 92.580  1.00 97.79  ?  162 ILE R CD1 1 
ATOM   7764 N N   . TRP E 5 163 ? 104.349 105.211 89.743  1.00 98.28  ?  163 TRP R N   1 
ATOM   7765 C CA  . TRP E 5 163 ? 104.182 103.874 89.183  1.00 98.28  ?  163 TRP R CA  1 
ATOM   7766 C C   . TRP E 5 163 ? 103.513 103.934 87.816  1.00 98.28  ?  163 TRP R C   1 
ATOM   7767 O O   . TRP E 5 163 ? 104.027 103.383 86.835  1.00 98.28  ?  163 TRP R O   1 
ATOM   7768 C CB  . TRP E 5 163 ? 103.362 103.000 90.134  1.00 98.28  ?  163 TRP R CB  1 
ATOM   7769 C CG  . TRP E 5 163 ? 104.150 102.386 91.252  1.00 98.28  ?  163 TRP R CG  1 
ATOM   7770 C CD1 . TRP E 5 163 ? 104.054 102.680 92.581  1.00 98.28  ?  163 TRP R CD1 1 
ATOM   7771 C CD2 . TRP E 5 163 ? 105.149 101.366 91.138  1.00 98.28  ?  163 TRP R CD2 1 
ATOM   7772 N NE1 . TRP E 5 163 ? 104.932 101.907 93.301  1.00 98.28  ?  163 TRP R NE1 1 
ATOM   7773 C CE2 . TRP E 5 163 ? 105.617 101.092 92.439  1.00 98.28  ?  163 TRP R CE2 1 
ATOM   7774 C CE3 . TRP E 5 163 ? 105.694 100.658 90.063  1.00 98.28  ?  163 TRP R CE3 1 
ATOM   7775 C CZ2 . TRP E 5 163 ? 106.604 100.142 92.692  1.00 98.28  ?  163 TRP R CZ2 1 
ATOM   7776 C CZ3 . TRP E 5 163 ? 106.673 99.716  90.317  1.00 98.28  ?  163 TRP R CZ3 1 
ATOM   7777 C CH2 . TRP E 5 163 ? 107.118 99.466  91.621  1.00 98.28  ?  163 TRP R CH2 1 
ATOM   7778 N N   . ILE E 5 164 ? 102.359 104.598 87.737  1.00 97.93  ?  164 ILE R N   1 
ATOM   7779 C CA  . ILE E 5 164 ? 101.590 104.615 86.496  1.00 97.93  ?  164 ILE R CA  1 
ATOM   7780 C C   . ILE E 5 164 ? 102.384 105.291 85.385  1.00 97.93  ?  164 ILE R C   1 
ATOM   7781 O O   . ILE E 5 164 ? 102.400 104.821 84.243  1.00 97.93  ?  164 ILE R O   1 
ATOM   7782 C CB  . ILE E 5 164 ? 100.227 105.297 86.719  1.00 97.93  ?  164 ILE R CB  1 
ATOM   7783 C CG1 . ILE E 5 164 ? 99.180  104.270 87.163  1.00 97.93  ?  164 ILE R CG1 1 
ATOM   7784 C CG2 . ILE E 5 164 ? 99.748  105.999 85.451  1.00 97.93  ?  164 ILE R CG2 1 
ATOM   7785 C CD1 . ILE E 5 164 ? 99.493  103.586 88.477  1.00 97.93  ?  164 ILE R CD1 1 
ATOM   7786 N N   . LEU E 5 165 ? 103.052 106.404 85.696  1.00 96.74  ?  165 LEU R N   1 
ATOM   7787 C CA  . LEU E 5 165 ? 103.815 107.116 84.677  1.00 96.74  ?  165 LEU R CA  1 
ATOM   7788 C C   . LEU E 5 165 ? 104.955 106.255 84.143  1.00 96.74  ?  165 LEU R C   1 
ATOM   7789 O O   . LEU E 5 165 ? 105.115 106.096 82.926  1.00 96.74  ?  165 LEU R O   1 
ATOM   7790 C CB  . LEU E 5 165 ? 104.347 108.432 85.247  1.00 96.74  ?  165 LEU R CB  1 
ATOM   7791 C CG  . LEU E 5 165 ? 103.471 109.663 84.999  1.00 96.74  ?  165 LEU R CG  1 
ATOM   7792 C CD1 . LEU E 5 165 ? 102.028 109.415 85.422  1.00 96.74  ?  165 LEU R CD1 1 
ATOM   7793 C CD2 . LEU E 5 165 ? 104.038 110.874 85.726  1.00 96.74  ?  165 LEU R CD2 1 
ATOM   7794 N N   . ILE E 5 166 ? 105.767 105.694 85.044  1.00 96.73  ?  166 ILE R N   1 
ATOM   7795 C CA  . ILE E 5 166 ? 106.906 104.888 84.611  1.00 96.73  ?  166 ILE R CA  1 
ATOM   7796 C C   . ILE E 5 166 ? 106.422 103.679 83.819  1.00 96.73  ?  166 ILE R C   1 
ATOM   7797 O O   . ILE E 5 166 ? 107.035 103.281 82.820  1.00 96.73  ?  166 ILE R O   1 
ATOM   7798 C CB  . ILE E 5 166 ? 107.763 104.472 85.821  1.00 96.73  ?  166 ILE R CB  1 
ATOM   7799 C CG1 . ILE E 5 166 ? 108.299 105.717 86.535  1.00 96.73  ?  166 ILE R CG1 1 
ATOM   7800 C CG2 . ILE E 5 166 ? 108.924 103.585 85.380  1.00 96.73  ?  166 ILE R CG2 1 
ATOM   7801 C CD1 . ILE E 5 166 ? 109.057 105.423 87.815  1.00 96.73  ?  166 ILE R CD1 1 
ATOM   7802 N N   . MET E 5 167 ? 105.306 103.081 84.244  1.00 96.43  ?  167 MET R N   1 
ATOM   7803 C CA  . MET E 5 167 ? 104.775 101.916 83.546  1.00 96.43  ?  167 MET R CA  1 
ATOM   7804 C C   . MET E 5 167 ? 104.303 102.283 82.144  1.00 96.43  ?  167 MET R C   1 
ATOM   7805 O O   . MET E 5 167 ? 104.637 101.609 81.164  1.00 96.43  ?  167 MET R O   1 
ATOM   7806 C CB  . MET E 5 167 ? 103.632 101.299 84.356  1.00 96.43  ?  167 MET R CB  1 
ATOM   7807 C CG  . MET E 5 167 ? 104.088 100.505 85.571  1.00 96.43  ?  167 MET R CG  1 
ATOM   7808 S SD  . MET E 5 167 ? 102.710 99.753  86.458  1.00 96.43  ?  167 MET R SD  1 
ATOM   7809 C CE  . MET E 5 167 ? 103.583 98.766  87.671  1.00 96.43  ?  167 MET R CE  1 
ATOM   7810 N N   . ALA E 5 168 ? 103.496 103.341 82.034  1.00 94.78  ?  168 ALA R N   1 
ATOM   7811 C CA  . ALA E 5 168 ? 103.012 103.767 80.726  1.00 94.78  ?  168 ALA R CA  1 
ATOM   7812 C C   . ALA E 5 168 ? 104.169 104.134 79.807  1.00 94.78  ?  168 ALA R C   1 
ATOM   7813 O O   . ALA E 5 168 ? 104.091 103.937 78.589  1.00 94.78  ?  168 ALA R O   1 
ATOM   7814 C CB  . ALA E 5 168 ? 102.056 104.949 80.879  1.00 94.78  ?  168 ALA R CB  1 
ATOM   7815 N N   . SER E 5 169 ? 105.254 104.669 80.372  1.00 92.02  ?  169 SER R N   1 
ATOM   7816 C CA  . SER E 5 169 ? 106.400 105.031 79.546  1.00 92.02  ?  169 SER R CA  1 
ATOM   7817 C C   . SER E 5 169 ? 107.145 103.793 79.062  1.00 92.02  ?  169 SER R C   1 
ATOM   7818 O O   . SER E 5 169 ? 107.455 103.673 77.870  1.00 92.02  ?  169 SER R O   1 
ATOM   7819 C CB  . SER E 5 169 ? 107.338 105.947 80.330  1.00 92.02  ?  169 SER R CB  1 
ATOM   7820 O OG  . SER E 5 169 ? 108.367 106.455 79.500  1.00 92.02  ?  169 SER R OG  1 
ATOM   7821 N N   . SER E 5 170 ? 107.437 102.856 79.969  1.00 91.68  ?  170 SER R N   1 
ATOM   7822 C CA  . SER E 5 170 ? 108.228 101.685 79.606  1.00 91.68  ?  170 SER R CA  1 
ATOM   7823 C C   . SER E 5 170 ? 107.401 100.597 78.931  1.00 91.68  ?  170 SER R C   1 
ATOM   7824 O O   . SER E 5 170 ? 107.966 99.576  78.525  1.00 91.68  ?  170 SER R O   1 
ATOM   7825 C CB  . SER E 5 170 ? 108.908 101.113 80.850  1.00 91.68  ?  170 SER R CB  1 
ATOM   7826 O OG  . SER E 5 170 ? 107.953 100.731 81.825  1.00 91.68  ?  170 SER R OG  1 
ATOM   7827 N N   . ILE E 5 171 ? 106.088 100.786 78.805  1.00 90.52  ?  171 ILE R N   1 
ATOM   7828 C CA  . ILE E 5 171 ? 105.214 99.799  78.177  1.00 90.52  ?  171 ILE R CA  1 
ATOM   7829 C C   . ILE E 5 171 ? 105.757 99.375  76.818  1.00 90.52  ?  171 ILE R C   1 
ATOM   7830 O O   . ILE E 5 171 ? 105.545 98.238  76.382  1.00 90.52  ?  171 ILE R O   1 
ATOM   7831 C CB  . ILE E 5 171 ? 103.783 100.354 78.041  1.00 90.52  ?  171 ILE R CB  1 
ATOM   7832 C CG1 . ILE E 5 171 ? 102.788 99.225  77.761  1.00 90.52  ?  171 ILE R CG1 1 
ATOM   7833 C CG2 . ILE E 5 171 ? 103.719 101.401 76.936  1.00 90.52  ?  171 ILE R CG2 1 
ATOM   7834 C CD1 . ILE E 5 171 ? 102.479 98.367  78.972  1.00 90.52  ?  171 ILE R CD1 1 
ATOM   7835 N N   . MET E 5 172 ? 106.460 100.284 76.138  1.00 86.44  ?  172 MET R N   1 
ATOM   7836 C CA  . MET E 5 172 ? 106.936 99.999  74.788  1.00 86.44  ?  172 MET R CA  1 
ATOM   7837 C C   . MET E 5 172 ? 107.796 98.740  74.755  1.00 86.44  ?  172 MET R C   1 
ATOM   7838 O O   . MET E 5 172 ? 107.782 97.989  73.773  1.00 86.44  ?  172 MET R O   1 
ATOM   7839 C CB  . MET E 5 172 ? 107.719 101.196 74.247  1.00 86.44  ?  172 MET R CB  1 
ATOM   7840 C CG  . MET E 5 172 ? 106.933 102.497 74.234  1.00 86.44  ?  172 MET R CG  1 
ATOM   7841 S SD  . MET E 5 172 ? 107.720 103.778 73.238  1.00 86.44  ?  172 MET R SD  1 
ATOM   7842 C CE  . MET E 5 172 ? 109.358 103.817 73.961  1.00 86.44  ?  172 MET R CE  1 
ATOM   7843 N N   . LEU E 5 173 ? 108.555 98.493  75.825  1.00 85.39  ?  173 LEU R N   1 
ATOM   7844 C CA  . LEU E 5 173 ? 109.473 97.359  75.837  1.00 85.39  ?  173 LEU R CA  1 
ATOM   7845 C C   . LEU E 5 173 ? 108.756 96.022  75.689  1.00 85.39  ?  173 LEU R C   1 
ATOM   7846 O O   . LEU E 5 173 ? 109.401 95.023  75.351  1.00 85.39  ?  173 LEU R O   1 
ATOM   7847 C CB  . LEU E 5 173 ? 110.293 97.367  77.130  1.00 85.39  ?  173 LEU R CB  1 
ATOM   7848 C CG  . LEU E 5 173 ? 111.294 96.222  77.307  1.00 85.39  ?  173 LEU R CG  1 
ATOM   7849 C CD1 . LEU E 5 173 ? 112.237 96.131  76.116  1.00 85.39  ?  173 LEU R CD1 1 
ATOM   7850 C CD2 . LEU E 5 173 ? 112.079 96.401  78.597  1.00 85.39  ?  173 LEU R CD2 1 
ATOM   7851 N N   . LEU E 5 174 ? 107.444 95.976  75.927  1.00 88.51  ?  174 LEU R N   1 
ATOM   7852 C CA  . LEU E 5 174 ? 106.711 94.717  75.842  1.00 88.51  ?  174 LEU R CA  1 
ATOM   7853 C C   . LEU E 5 174 ? 106.715 94.119  74.441  1.00 88.51  ?  174 LEU R C   1 
ATOM   7854 O O   . LEU E 5 174 ? 106.352 92.948  74.289  1.00 88.51  ?  174 LEU R O   1 
ATOM   7855 C CB  . LEU E 5 174 ? 105.264 94.919  76.299  1.00 88.51  ?  174 LEU R CB  1 
ATOM   7856 C CG  . LEU E 5 174 ? 105.045 95.261  77.774  1.00 88.51  ?  174 LEU R CG  1 
ATOM   7857 C CD1 . LEU E 5 174 ? 103.563 95.453  78.047  1.00 88.51  ?  174 LEU R CD1 1 
ATOM   7858 C CD2 . LEU E 5 174 ? 105.619 94.184  78.683  1.00 88.51  ?  174 LEU R CD2 1 
ATOM   7859 N N   . ASP E 5 175 ? 107.111 94.880  73.422  1.00 84.26  ?  175 ASP R N   1 
ATOM   7860 C CA  . ASP E 5 175 ? 107.121 94.377  72.054  1.00 84.26  ?  175 ASP R CA  1 
ATOM   7861 C C   . ASP E 5 175 ? 108.324 93.492  71.752  1.00 84.26  ?  175 ASP R C   1 
ATOM   7862 O O   . ASP E 5 175 ? 108.477 93.058  70.605  1.00 84.26  ?  175 ASP R O   1 
ATOM   7863 C CB  . ASP E 5 175 ? 107.084 95.547  71.065  1.00 84.26  ?  175 ASP R CB  1 
ATOM   7864 C CG  . ASP E 5 175 ? 108.243 96.506  71.249  1.00 84.26  ?  175 ASP R CG  1 
ATOM   7865 O OD1 . ASP E 5 175 ? 109.076 96.273  72.151  1.00 84.26  ?  175 ASP R OD1 1 
ATOM   7866 O OD2 . ASP E 5 175 ? 108.321 97.496  70.491  1.00 84.26  ?  175 ASP R OD2 1 
ATOM   7867 N N   . SER E 5 176 ? 109.202 93.275  72.741  1.00 79.27  ?  176 SER R N   1 
ATOM   7868 C CA  . SER E 5 176 ? 110.392 92.455  72.550  1.00 79.27  ?  176 SER R CA  1 
ATOM   7869 C C   . SER E 5 176 ? 110.024 91.061  72.088  1.00 79.27  ?  176 SER R C   1 
ATOM   7870 O O   . SER E 5 176 ? 109.333 90.331  72.796  1.00 79.27  ?  176 SER R O   1 
ATOM   7871 C CB  . SER E 5 176 ? 111.193 92.379  73.853  1.00 79.27  ?  176 SER R CB  1 
ATOM   7872 O OG  . SER E 5 176 ? 110.353 92.081  74.956  1.00 79.27  ?  176 SER R OG  1 
ATOM   7873 N N   . GLY E 5 177 ? 110.501 90.676  70.913  1.00 85.06  ?  177 GLY R N   1 
ATOM   7874 C CA  . GLY E 5 177 ? 110.180 89.374  70.367  1.00 85.06  ?  177 GLY R CA  1 
ATOM   7875 C C   . GLY E 5 177 ? 110.901 88.254  71.071  1.00 85.06  ?  177 GLY R C   1 
ATOM   7876 O O   . GLY E 5 177 ? 111.863 88.494  71.803  1.00 85.06  ?  177 GLY R O   1 
ATOM   7877 N N   . SER E 5 178 ? 110.432 87.028  70.876  1.00 87.93  ?  178 SER R N   1 
ATOM   7878 C CA  . SER E 5 178 ? 111.113 85.871  71.447  1.00 87.93  ?  178 SER R CA  1 
ATOM   7879 C C   . SER E 5 178 ? 112.502 85.838  70.835  1.00 87.93  ?  178 SER R C   1 
ATOM   7880 O O   . SER E 5 178 ? 113.455 85.435  71.503  1.00 87.93  ?  178 SER R O   1 
ATOM   7881 C CB  . SER E 5 178 ? 110.364 84.573  71.125  1.00 87.93  ?  178 SER R CB  1 
ATOM   7882 O OG  . SER E 5 178 ? 110.852 83.475  71.876  1.00 87.93  ?  178 SER R OG  1 
ATOM   7883 N N   . GLU E 5 179 ? 112.612 86.223  69.561  1.00 87.19  ?  179 GLU R N   1 
ATOM   7884 C CA  . GLU E 5 179 ? 113.900 86.241  68.860  1.00 87.19  ?  179 GLU R CA  1 
ATOM   7885 C C   . GLU E 5 179 ? 114.505 84.846  68.836  1.00 87.19  ?  179 GLU R C   1 
ATOM   7886 O O   . GLU E 5 179 ? 115.716 84.680  68.964  1.00 87.19  ?  179 GLU R O   1 
ATOM   7887 C CB  . GLU E 5 179 ? 114.881 87.267  69.473  1.00 87.19  ?  179 GLU R CB  1 
ATOM   7888 C CG  . GLU E 5 179 ? 114.383 88.707  69.532  1.00 87.19  ?  179 GLU R CG  1 
ATOM   7889 C CD  . GLU E 5 179 ? 114.596 89.496  68.249  1.00 87.19  ?  179 GLU R CD  1 
ATOM   7890 O OE1 . GLU E 5 179 ? 114.853 88.892  67.186  1.00 87.19  ?  179 GLU R OE1 1 
ATOM   7891 O OE2 . GLU E 5 179 ? 114.492 90.739  68.305  1.00 87.19  ?  179 GLU R OE2 1 
ATOM   7892 N N   . GLN E 5 180 ? 113.658 83.838  68.659  1.00 86.38  ?  180 GLN R N   1 
ATOM   7893 C CA  . GLN E 5 180 ? 114.159 82.474  68.605  1.00 86.38  ?  180 GLN R CA  1 
ATOM   7894 C C   . GLN E 5 180 ? 115.063 82.292  67.403  1.00 86.38  ?  180 GLN R C   1 
ATOM   7895 O O   . GLN E 5 180 ? 114.710 82.720  66.303  1.00 86.38  ?  180 GLN R O   1 
ATOM   7896 C CB  . GLN E 5 180 ? 113.019 81.453  68.560  1.00 86.38  ?  180 GLN R CB  1 
ATOM   7897 C CG  . GLN E 5 180 ? 113.510 80.011  68.626  1.00 86.38  ?  180 GLN R CG  1 
ATOM   7898 C CD  . GLN E 5 180 ? 112.409 79.010  68.919  1.00 86.38  ?  180 GLN R CD  1 
ATOM   7899 O OE1 . GLN E 5 180 ? 111.223 79.302  68.763  1.00 86.38  ?  180 GLN R OE1 1 
ATOM   7900 N NE2 . GLN E 5 180 ? 112.801 77.809  69.335  1.00 86.38  ?  180 GLN R NE2 1 
ATOM   7901 N N   . ASN E 5 181 ? 116.221 81.668  67.607  1.00 82.77  ?  181 ASN R N   1 
ATOM   7902 C CA  . ASN E 5 181 ? 117.152 81.395  66.514  1.00 82.77  ?  181 ASN R CA  1 
ATOM   7903 C C   . ASN E 5 181 ? 117.538 79.925  66.598  1.00 82.77  ?  181 ASN R C   1 
ATOM   7904 O O   . ASN E 5 181 ? 118.095 79.485  67.600  1.00 82.77  ?  181 ASN R O   1 
ATOM   7905 C CB  . ASN E 5 181 ? 118.385 82.309  66.601  1.00 82.77  ?  181 ASN R CB  1 
ATOM   7906 C CG  . ASN E 5 181 ? 118.964 82.405  68.009  1.00 82.77  ?  181 ASN R CG  1 
ATOM   7907 O OD1 . ASN E 5 181 ? 118.394 83.060  68.882  1.00 82.77  ?  181 ASN R OD1 1 
ATOM   7908 N ND2 . ASN E 5 181 ? 120.105 81.763  68.230  1.00 82.77  ?  181 ASN R ND2 1 
ATOM   7909 N N   . GLY E 5 182 ? 117.272 79.159  65.548  1.00 84.13  ?  182 GLY R N   1 
ATOM   7910 C CA  . GLY E 5 182 ? 117.559 77.739  65.594  1.00 84.13  ?  182 GLY R CA  1 
ATOM   7911 C C   . GLY E 5 182 ? 116.845 77.078  66.759  1.00 84.13  ?  182 GLY R C   1 
ATOM   7912 O O   . GLY E 5 182 ? 115.643 77.289  66.936  1.00 84.13  ?  182 GLY R O   1 
ATOM   7913 N N   . SER E 5 183 ? 117.569 76.297  67.560  1.00 87.81  ?  183 SER R N   1 
ATOM   7914 C CA  . SER E 5 183 ? 116.977 75.583  68.696  1.00 87.81  ?  183 SER R CA  1 
ATOM   7915 C C   . SER E 5 183 ? 117.004 76.366  70.003  1.00 87.81  ?  183 SER R C   1 
ATOM   7916 O O   . SER E 5 183 ? 116.489 75.872  71.009  1.00 87.81  ?  183 SER R O   1 
ATOM   7917 C CB  . SER E 5 183 ? 117.729 74.269  68.901  1.00 87.81  ?  183 SER R CB  1 
ATOM   7918 O OG  . SER E 5 183 ? 119.078 74.521  69.254  1.00 87.81  ?  183 SER R OG  1 
ATOM   7919 N N   . VAL E 5 184 ? 117.577 77.570  70.002  1.00 89.56  ?  184 VAL R N   1 
ATOM   7920 C CA  . VAL E 5 184 ? 117.727 78.358  71.236  1.00 89.56  ?  184 VAL R CA  1 
ATOM   7921 C C   . VAL E 5 184 ? 117.026 79.694  71.087  1.00 89.56  ?  184 VAL R C   1 
ATOM   7922 O O   . VAL E 5 184 ? 116.808 80.145  69.970  1.00 89.56  ?  184 VAL R O   1 
ATOM   7923 C CB  . VAL E 5 184 ? 119.217 78.579  71.610  1.00 89.56  ?  184 VAL R CB  1 
ATOM   7924 C CG1 . VAL E 5 184 ? 120.009 77.290  71.436  1.00 89.56  ?  184 VAL R CG1 1 
ATOM   7925 C CG2 . VAL E 5 184 ? 119.856 79.700  70.796  1.00 89.56  ?  184 VAL R CG2 1 
ATOM   7926 N N   . THR E 5 185 ? 116.652 80.310  72.204  1.00 92.36  ?  185 THR R N   1 
ATOM   7927 C CA  . THR E 5 185 ? 115.952 81.589  72.175  1.00 92.36  ?  185 THR R CA  1 
ATOM   7928 C C   . THR E 5 185 ? 116.833 82.669  72.770  1.00 92.36  ?  185 THR R C   1 
ATOM   7929 O O   . THR E 5 185 ? 117.337 82.492  73.874  1.00 92.36  ?  185 THR R O   1 
ATOM   7930 C CB  . THR E 5 185 ? 114.666 81.486  72.999  1.00 92.36  ?  185 THR R CB  1 
ATOM   7931 O OG1 . THR E 5 185 ? 115.011 81.127  74.344  1.00 92.36  ?  185 THR R OG1 1 
ATOM   7932 C CG2 . THR E 5 185 ? 113.743 80.433  72.428  1.00 92.36  ?  185 THR R CG2 1 
ATOM   7933 N N   . SER E 5 186 ? 117.037 83.771  72.045  1.00 89.47  ?  186 SER R N   1 
ATOM   7934 C CA  . SER E 5 186 ? 117.840 84.883  72.559  1.00 89.47  ?  186 SER R CA  1 
ATOM   7935 C C   . SER E 5 186 ? 117.008 85.878  73.365  1.00 89.47  ?  186 SER R C   1 
ATOM   7936 O O   . SER E 5 186 ? 116.905 87.049  72.991  1.00 89.47  ?  186 SER R O   1 
ATOM   7937 C CB  . SER E 5 186 ? 118.586 85.584  71.418  1.00 89.47  ?  186 SER R CB  1 
ATOM   7938 O OG  . SER E 5 186 ? 117.707 86.084  70.432  1.00 89.47  ?  186 SER R OG  1 
ATOM   7939 N N   . CYS E 5 187 ? 116.416 85.431  74.469  1.00 89.41  ?  187 CYS R N   1 
ATOM   7940 C CA  . CYS E 5 187 ? 115.683 86.345  75.349  1.00 89.41  ?  187 CYS R CA  1 
ATOM   7941 C C   . CYS E 5 187 ? 116.718 87.103  76.163  1.00 89.41  ?  187 CYS R C   1 
ATOM   7942 O O   . CYS E 5 187 ? 117.816 86.593  76.364  1.00 89.41  ?  187 CYS R O   1 
ATOM   7943 C CB  . CYS E 5 187 ? 114.720 85.589  76.267  1.00 89.41  ?  187 CYS R CB  1 
ATOM   7944 S SG  . CYS E 5 187 ? 113.928 86.615  77.528  1.00 89.41  ?  187 CYS R SG  1 
ATOM   7945 N N   . LEU E 5 188 ? 116.398 88.315  76.613  1.00 80.90  ?  188 LEU R N   1 
ATOM   7946 C CA  . LEU E 5 188 ? 117.313 89.105  77.450  1.00 80.90  ?  188 LEU R CA  1 
ATOM   7947 C C   . LEU E 5 188 ? 118.588 89.462  76.699  1.00 80.90  ?  188 LEU R C   1 
ATOM   7948 O O   . LEU E 5 188 ? 119.619 89.699  77.329  1.00 80.90  ?  188 LEU R O   1 
ATOM   7949 C CB  . LEU E 5 188 ? 117.666 88.375  78.762  1.00 80.90  ?  188 LEU R CB  1 
ATOM   7950 C CG  . LEU E 5 188 ? 116.564 87.595  79.486  1.00 80.90  ?  188 LEU R CG  1 
ATOM   7951 C CD1 . LEU E 5 188 ? 117.139 86.761  80.616  1.00 80.90  ?  188 LEU R CD1 1 
ATOM   7952 C CD2 . LEU E 5 188 ? 115.407 88.493  79.927  1.00 80.90  ?  188 LEU R CD2 1 
ATOM   7953 N N   . GLU E 5 189 ? 118.521 89.531  75.370  1.00 79.96  ?  189 GLU R N   1 
ATOM   7954 C CA  . GLU E 5 189 ? 119.704 89.815  74.555  1.00 79.96  ?  189 GLU R CA  1 
ATOM   7955 C C   . GLU E 5 189 ? 119.380 90.826  73.471  1.00 79.96  ?  189 GLU R C   1 
ATOM   7956 O O   . GLU E 5 189 ? 118.248 90.873  72.988  1.00 79.96  ?  189 GLU R O   1 
ATOM   7957 C CB  . GLU E 5 189 ? 120.253 88.525  73.944  1.00 79.96  ?  189 GLU R CB  1 
ATOM   7958 C CG  . GLU E 5 189 ? 120.921 87.605  74.961  1.00 79.96  ?  189 GLU R CG  1 
ATOM   7959 C CD  . GLU E 5 189 ? 121.569 86.379  74.344  1.00 79.96  ?  189 GLU R CD  1 
ATOM   7960 O OE1 . GLU E 5 189 ? 121.491 86.196  73.111  1.00 79.96  ?  189 GLU R OE1 1 
ATOM   7961 O OE2 . GLU E 5 189 ? 122.161 85.587  75.106  1.00 79.96  ?  189 GLU R OE2 1 
ATOM   7962 N N   . LEU E 5 190 ? 120.369 91.624  73.079  1.00 77.69  ?  190 LEU R N   1 
ATOM   7963 C CA  . LEU E 5 190 ? 120.143 92.675  72.087  1.00 77.69  ?  190 LEU R CA  1 
ATOM   7964 C C   . LEU E 5 190 ? 120.131 92.159  70.656  1.00 77.69  ?  190 LEU R C   1 
ATOM   7965 O O   . LEU E 5 190 ? 120.958 91.309  70.320  1.00 77.69  ?  190 LEU R O   1 
ATOM   7966 C CB  . LEU E 5 190 ? 121.224 93.760  72.217  1.00 77.69  ?  190 LEU R CB  1 
ATOM   7967 C CG  . LEU E 5 190 ? 121.187 94.980  71.282  1.00 77.69  ?  190 LEU R CG  1 
ATOM   7968 C CD1 . LEU E 5 190 ? 119.880 95.746  71.405  1.00 77.69  ?  190 LEU R CD1 1 
ATOM   7969 C CD2 . LEU E 5 190 ? 122.366 95.903  71.559  1.00 77.69  ?  190 LEU R CD2 1 
ATOM   7970 N N   . ASN E 5 191 ? 119.209 92.648  69.821  1.00 75.00  ?  191 ASN R N   1 
ATOM   7971 C CA  . ASN E 5 191 ? 119.175 92.301  68.409  1.00 75.00  ?  191 ASN R CA  1 
ATOM   7972 C C   . ASN E 5 191 ? 118.916 93.562  67.598  1.00 75.00  ?  191 ASN R C   1 
ATOM   7973 O O   . ASN E 5 191 ? 118.608 94.627  68.142  1.00 75.00  ?  191 ASN R O   1 
ATOM   7974 C CB  . ASN E 5 191 ? 118.105 91.241  68.116  1.00 75.00  ?  191 ASN R CB  1 
ATOM   7975 C CG  . ASN E 5 191 ? 118.346 89.945  68.866  1.00 75.00  ?  191 ASN R CG  1 
ATOM   7976 O OD1 . ASN E 5 191 ? 119.037 89.050  68.377  1.00 75.00  ?  191 ASN R OD1 1 
ATOM   7977 N ND2 . ASN E 5 191 ? 117.774 89.837  70.059  1.00 75.00  ?  191 ASN R ND2 1 
ATOM   7978 N N   . LEU E 5 192 ? 119.045 93.433  66.276  1.00 74.89  ?  192 LEU R N   1 
ATOM   7979 C CA  . LEU E 5 192 ? 118.829 94.580  65.400  1.00 74.89  ?  192 LEU R CA  1 
ATOM   7980 C C   . LEU E 5 192 ? 117.408 95.114  65.520  1.00 74.89  ?  192 LEU R C   1 
ATOM   7981 O O   . LEU E 5 192 ? 117.205 96.334  65.565  1.00 74.89  ?  192 LEU R O   1 
ATOM   7982 C CB  . LEU E 5 192 ? 119.130 94.195  63.951  1.00 74.89  ?  192 LEU R CB  1 
ATOM   7983 C CG  . LEU E 5 192 ? 118.971 95.303  62.906  1.00 74.89  ?  192 LEU R CG  1 
ATOM   7984 C CD1 . LEU E 5 192 ? 119.905 96.467  63.200  1.00 74.89  ?  192 LEU R CD1 1 
ATOM   7985 C CD2 . LEU E 5 192 ? 119.219 94.755  61.510  1.00 74.89  ?  192 LEU R CD2 1 
ATOM   7986 N N   . TYR E 5 193 ? 116.416 94.223  65.582  1.00 76.17  ?  193 TYR R N   1 
ATOM   7987 C CA  . TYR E 5 193 ? 115.028 94.664  65.678  1.00 76.17  ?  193 TYR R CA  1 
ATOM   7988 C C   . TYR E 5 193 ? 114.799 95.534  66.906  1.00 76.17  ?  193 TYR R C   1 
ATOM   7989 O O   . TYR E 5 193 ? 113.909 96.392  66.899  1.00 76.17  ?  193 TYR R O   1 
ATOM   7990 C CB  . TYR E 5 193 ? 114.094 93.453  65.710  1.00 76.17  ?  193 TYR R CB  1 
ATOM   7991 C CG  . TYR E 5 193 ? 114.267 92.504  64.542  1.00 76.17  ?  193 TYR R CG  1 
ATOM   7992 C CD1 . TYR E 5 193 ? 114.721 92.959  63.310  1.00 76.17  ?  193 TYR R CD1 1 
ATOM   7993 C CD2 . TYR E 5 193 ? 113.978 91.153  64.674  1.00 76.17  ?  193 TYR R CD2 1 
ATOM   7994 C CE1 . TYR E 5 193 ? 114.880 92.095  62.244  1.00 76.17  ?  193 TYR R CE1 1 
ATOM   7995 C CE2 . TYR E 5 193 ? 114.134 90.281  63.613  1.00 76.17  ?  193 TYR R CE2 1 
ATOM   7996 C CZ  . TYR E 5 193 ? 114.585 90.757  62.401  1.00 76.17  ?  193 TYR R CZ  1 
ATOM   7997 O OH  . TYR E 5 193 ? 114.742 89.892  61.342  1.00 76.17  ?  193 TYR R OH  1 
ATOM   7998 N N   . LYS E 5 194 ? 115.584 95.331  67.964  1.00 79.96  ?  194 LYS R N   1 
ATOM   7999 C CA  . LYS E 5 194 ? 115.462 96.105  69.191  1.00 79.96  ?  194 LYS R CA  1 
ATOM   8000 C C   . LYS E 5 194 ? 116.326 97.362  69.191  1.00 79.96  ?  194 LYS R C   1 
ATOM   8001 O O   . LYS E 5 194 ? 116.592 97.910  70.266  1.00 79.96  ?  194 LYS R O   1 
ATOM   8002 C CB  . LYS E 5 194 ? 115.821 95.231  70.396  1.00 79.96  ?  194 LYS R CB  1 
ATOM   8003 C CG  . LYS E 5 194 ? 114.971 93.977  70.525  1.00 79.96  ?  194 LYS R CG  1 
ATOM   8004 C CD  . LYS E 5 194 ? 115.369 93.154  71.740  1.00 79.96  ?  194 LYS R CD  1 
ATOM   8005 C CE  . LYS E 5 194 ? 114.551 91.877  71.835  1.00 79.96  ?  194 LYS R CE  1 
ATOM   8006 N NZ  . LYS E 5 194 ? 114.916 91.062  73.027  1.00 79.96  1  194 LYS R NZ  1 
ATOM   8007 N N   . ILE E 5 195 ? 116.769 97.832  68.024  1.00 81.28  ?  195 ILE R N   1 
ATOM   8008 C CA  . ILE E 5 195 ? 117.621 99.016  67.976  1.00 81.28  ?  195 ILE R CA  1 
ATOM   8009 C C   . ILE E 5 195 ? 116.784 100.278 67.806  1.00 81.28  ?  195 ILE R C   1 
ATOM   8010 O O   . ILE E 5 195 ? 116.882 101.215 68.606  1.00 81.28  ?  195 ILE R O   1 
ATOM   8011 C CB  . ILE E 5 195 ? 118.662 98.875  66.849  1.00 81.28  ?  195 ILE R CB  1 
ATOM   8012 C CG1 . ILE E 5 195 ? 119.574 97.669  67.104  1.00 81.28  ?  195 ILE R CG1 1 
ATOM   8013 C CG2 . ILE E 5 195 ? 119.484 100.150 66.720  1.00 81.28  ?  195 ILE R CG2 1 
ATOM   8014 C CD1 . ILE E 5 195 ? 120.439 97.784  68.346  1.00 81.28  ?  195 ILE R CD1 1 
ATOM   8015 N N   . ALA E 5 196 ? 115.944 100.316 66.767  1.00 84.18  ?  196 ALA R N   1 
ATOM   8016 C CA  . ALA E 5 196 ? 115.180 101.523 66.465  1.00 84.18  ?  196 ALA R CA  1 
ATOM   8017 C C   . ALA E 5 196 ? 114.441 102.051 67.687  1.00 84.18  ?  196 ALA R C   1 
ATOM   8018 O O   . ALA E 5 196 ? 114.210 103.261 67.797  1.00 84.18  ?  196 ALA R O   1 
ATOM   8019 C CB  . ALA E 5 196 ? 114.194 101.246 65.331  1.00 84.18  ?  196 ALA R CB  1 
ATOM   8020 N N   . LYS E 5 197 ? 114.064 101.169 68.614  1.00 85.49  ?  197 LYS R N   1 
ATOM   8021 C CA  . LYS E 5 197 ? 113.379 101.610 69.824  1.00 85.49  ?  197 LYS R CA  1 
ATOM   8022 C C   . LYS E 5 197 ? 114.374 102.056 70.889  1.00 85.49  ?  197 LYS R C   1 
ATOM   8023 O O   . LYS E 5 197 ? 114.212 103.122 71.494  1.00 85.49  ?  197 LYS R O   1 
ATOM   8024 C CB  . LYS E 5 197 ? 112.479 100.491 70.356  1.00 85.49  ?  197 LYS R CB  1 
ATOM   8025 C CG  . LYS E 5 197 ? 113.206 99.185  70.670  1.00 85.49  ?  197 LYS R CG  1 
ATOM   8026 C CD  . LYS E 5 197 ? 112.247 98.086  71.114  1.00 85.49  ?  197 LYS R CD  1 
ATOM   8027 C CE  . LYS E 5 197 ? 111.254 97.706  70.021  1.00 85.49  ?  197 LYS R CE  1 
ATOM   8028 N NZ  . LYS E 5 197 ? 111.916 97.371  68.729  1.00 85.49  1  197 LYS R NZ  1 
ATOM   8029 N N   . LEU E 5 198 ? 115.419 101.258 71.125  1.00 85.52  ?  198 LEU R N   1 
ATOM   8030 C CA  . LEU E 5 198 ? 116.388 101.603 72.160  1.00 85.52  ?  198 LEU R CA  1 
ATOM   8031 C C   . LEU E 5 198 ? 117.088 102.919 71.856  1.00 85.52  ?  198 LEU R C   1 
ATOM   8032 O O   . LEU E 5 198 ? 117.433 103.665 72.778  1.00 85.52  ?  198 LEU R O   1 
ATOM   8033 C CB  . LEU E 5 198 ? 117.413 100.479 72.317  1.00 85.52  ?  198 LEU R CB  1 
ATOM   8034 C CG  . LEU E 5 198 ? 116.886 99.177  72.924  1.00 85.52  ?  198 LEU R CG  1 
ATOM   8035 C CD1 . LEU E 5 198 ? 117.968 98.110  72.918  1.00 85.52  ?  198 LEU R CD1 1 
ATOM   8036 C CD2 . LEU E 5 198 ? 116.370 99.406  74.334  1.00 85.52  ?  198 LEU R CD2 1 
ATOM   8037 N N   . GLN E 5 199 ? 117.305 103.224 70.575  1.00 87.61  ?  199 GLN R N   1 
ATOM   8038 C CA  . GLN E 5 199 ? 117.945 104.484 70.216  1.00 87.61  ?  199 GLN R CA  1 
ATOM   8039 C C   . GLN E 5 199 ? 117.089 105.689 70.580  1.00 87.61  ?  199 GLN R C   1 
ATOM   8040 O O   . GLN E 5 199 ? 117.590 106.819 70.557  1.00 87.61  ?  199 GLN R O   1 
ATOM   8041 C CB  . GLN E 5 199 ? 118.259 104.503 68.719  1.00 87.61  ?  199 GLN R CB  1 
ATOM   8042 C CG  . GLN E 5 199 ? 119.237 103.425 68.273  1.00 87.61  ?  199 GLN R CG  1 
ATOM   8043 C CD  . GLN E 5 199 ? 120.625 103.614 68.854  1.00 87.61  ?  199 GLN R CD  1 
ATOM   8044 O OE1 . GLN E 5 199 ? 120.911 104.625 69.495  1.00 87.61  ?  199 GLN R OE1 1 
ATOM   8045 N NE2 . GLN E 5 199 ? 121.497 102.638 68.631  1.00 87.61  ?  199 GLN R NE2 1 
ATOM   8046 N N   . THR E 5 200 ? 115.815 105.480 70.916  1.00 88.23  ?  200 THR R N   1 
ATOM   8047 C CA  . THR E 5 200 ? 114.905 106.570 71.251  1.00 88.23  ?  200 THR R CA  1 
ATOM   8048 C C   . THR E 5 200 ? 114.664 106.697 72.750  1.00 88.23  ?  200 THR R C   1 
ATOM   8049 O O   . THR E 5 200 ? 114.872 107.771 73.321  1.00 88.23  ?  200 THR R O   1 
ATOM   8050 C CB  . THR E 5 200 ? 113.565 106.374 70.530  1.00 88.23  ?  200 THR R CB  1 
ATOM   8051 O OG1 . THR E 5 200 ? 112.989 105.119 70.914  1.00 88.23  ?  200 THR R OG1 1 
ATOM   8052 C CG2 . THR E 5 200 ? 113.759 106.401 69.020  1.00 88.23  ?  200 THR R CG2 1 
ATOM   8053 N N   . MET E 5 201 ? 114.231 105.617 73.405  1.00 89.45  ?  201 MET R N   1 
ATOM   8054 C CA  . MET E 5 201 ? 113.887 105.687 74.821  1.00 89.45  ?  201 MET R CA  1 
ATOM   8055 C C   . MET E 5 201 ? 115.095 105.542 75.737  1.00 89.45  ?  201 MET R C   1 
ATOM   8056 O O   . MET E 5 201 ? 114.933 105.630 76.959  1.00 89.45  ?  201 MET R O   1 
ATOM   8057 C CB  . MET E 5 201 ? 112.851 104.611 75.161  1.00 89.45  ?  201 MET R CB  1 
ATOM   8058 C CG  . MET E 5 201 ? 113.309 103.181 74.908  1.00 89.45  ?  201 MET R CG  1 
ATOM   8059 S SD  . MET E 5 201 ? 112.016 101.983 75.291  1.00 89.45  ?  201 MET R SD  1 
ATOM   8060 C CE  . MET E 5 201 ? 112.815 100.445 74.840  1.00 89.45  ?  201 MET R CE  1 
ATOM   8061 N N   . ASN E 5 202 ? 116.292 105.326 75.189  1.00 92.51  ?  202 ASN R N   1 
ATOM   8062 C CA  . ASN E 5 202 ? 117.475 105.194 76.034  1.00 92.51  ?  202 ASN R CA  1 
ATOM   8063 C C   . ASN E 5 202 ? 117.891 106.543 76.607  1.00 92.51  ?  202 ASN R C   1 
ATOM   8064 O O   . ASN E 5 202 ? 117.920 106.728 77.830  1.00 92.51  ?  202 ASN R O   1 
ATOM   8065 C CB  . ASN E 5 202 ? 118.621 104.573 75.235  1.00 92.51  ?  202 ASN R CB  1 
ATOM   8066 C CG  . ASN E 5 202 ? 119.907 104.482 76.033  1.00 92.51  ?  202 ASN R CG  1 
ATOM   8067 O OD1 . ASN E 5 202 ? 120.178 103.473 76.683  1.00 92.51  ?  202 ASN R OD1 1 
ATOM   8068 N ND2 . ASN E 5 202 ? 120.711 105.539 75.983  1.00 92.51  ?  202 ASN R ND2 1 
ATOM   8069 N N   . TYR E 5 203 ? 118.213 107.503 75.735  1.00 91.41  ?  203 TYR R N   1 
ATOM   8070 C CA  . TYR E 5 203 ? 118.669 108.808 76.203  1.00 91.41  ?  203 TYR R CA  1 
ATOM   8071 C C   . TYR E 5 203 ? 117.678 109.436 77.174  1.00 91.41  ?  203 TYR R C   1 
ATOM   8072 O O   . TYR E 5 203 ? 118.089 110.112 78.124  1.00 91.41  ?  203 TYR R O   1 
ATOM   8073 C CB  . TYR E 5 203 ? 118.903 109.738 75.014  1.00 91.41  ?  203 TYR R CB  1 
ATOM   8074 C CG  . TYR E 5 203 ? 120.064 109.326 74.137  1.00 91.41  ?  203 TYR R CG  1 
ATOM   8075 C CD1 . TYR E 5 203 ? 121.339 109.829 74.360  1.00 91.41  ?  203 TYR R CD1 1 
ATOM   8076 C CD2 . TYR E 5 203 ? 119.886 108.436 73.087  1.00 91.41  ?  203 TYR R CD2 1 
ATOM   8077 C CE1 . TYR E 5 203 ? 122.404 109.457 73.563  1.00 91.41  ?  203 TYR R CE1 1 
ATOM   8078 C CE2 . TYR E 5 203 ? 120.945 108.057 72.284  1.00 91.41  ?  203 TYR R CE2 1 
ATOM   8079 C CZ  . TYR E 5 203 ? 122.202 108.571 72.526  1.00 91.41  ?  203 TYR R CZ  1 
ATOM   8080 O OH  . TYR E 5 203 ? 123.259 108.197 71.729  1.00 91.41  ?  203 TYR R OH  1 
ATOM   8081 N N   . ILE E 5 204 ? 116.379 109.225 76.958  1.00 91.93  ?  204 ILE R N   1 
ATOM   8082 C CA  . ILE E 5 204 ? 115.383 109.735 77.894  1.00 91.93  ?  204 ILE R CA  1 
ATOM   8083 C C   . ILE E 5 204 ? 115.691 109.245 79.303  1.00 91.93  ?  204 ILE R C   1 
ATOM   8084 O O   . ILE E 5 204 ? 115.823 110.040 80.242  1.00 91.93  ?  204 ILE R O   1 
ATOM   8085 C CB  . ILE E 5 204 ? 113.968 109.324 77.449  1.00 91.93  ?  204 ILE R CB  1 
ATOM   8086 C CG1 . ILE E 5 204 ? 113.647 109.926 76.078  1.00 91.93  ?  204 ILE R CG1 1 
ATOM   8087 C CG2 . ILE E 5 204 ? 112.935 109.762 78.486  1.00 91.93  ?  204 ILE R CG2 1 
ATOM   8088 C CD1 . ILE E 5 204 ? 112.336 109.450 75.485  1.00 91.93  ?  204 ILE R CD1 1 
ATOM   8089 N N   . ALA E 5 205 ? 115.830 107.927 79.467  1.00 92.45  ?  205 ALA R N   1 
ATOM   8090 C CA  . ALA E 5 205 ? 116.136 107.375 80.782  1.00 92.45  ?  205 ALA R CA  1 
ATOM   8091 C C   . ALA E 5 205 ? 117.433 107.945 81.338  1.00 92.45  ?  205 ALA R C   1 
ATOM   8092 O O   . ALA E 5 205 ? 117.621 107.982 82.560  1.00 92.45  ?  205 ALA R O   1 
ATOM   8093 C CB  . ALA E 5 205 ? 116.217 105.850 80.705  1.00 92.45  ?  205 ALA R CB  1 
ATOM   8094 N N   . LEU E 5 206 ? 118.338 108.392 80.465  1.00 93.31  ?  206 LEU R N   1 
ATOM   8095 C CA  . LEU E 5 206 ? 119.586 108.981 80.940  1.00 93.31  ?  206 LEU R CA  1 
ATOM   8096 C C   . LEU E 5 206 ? 119.345 110.350 81.563  1.00 93.31  ?  206 LEU R C   1 
ATOM   8097 O O   . LEU E 5 206 ? 119.985 110.709 82.558  1.00 93.31  ?  206 LEU R O   1 
ATOM   8098 C CB  . LEU E 5 206 ? 120.587 109.083 79.789  1.00 93.31  ?  206 LEU R CB  1 
ATOM   8099 C CG  . LEU E 5 206 ? 121.972 109.640 80.132  1.00 93.31  ?  206 LEU R CG  1 
ATOM   8100 C CD1 . LEU E 5 206 ? 122.696 108.738 81.118  1.00 93.31  ?  206 LEU R CD1 1 
ATOM   8101 C CD2 . LEU E 5 206 ? 122.796 109.822 78.866  1.00 93.31  ?  206 LEU R CD2 1 
ATOM   8102 N N   . VAL E 5 207 ? 118.420 111.125 80.997  1.00 93.28  ?  207 VAL R N   1 
ATOM   8103 C CA  . VAL E 5 207 ? 118.194 112.487 81.472  1.00 93.28  ?  207 VAL R CA  1 
ATOM   8104 C C   . VAL E 5 207 ? 117.340 112.484 82.734  1.00 93.28  ?  207 VAL R C   1 
ATOM   8105 O O   . VAL E 5 207 ? 117.772 112.939 83.800  1.00 93.28  ?  207 VAL R O   1 
ATOM   8106 C CB  . VAL E 5 207 ? 117.550 113.341 80.364  1.00 93.28  ?  207 VAL R CB  1 
ATOM   8107 C CG1 . VAL E 5 207 ? 117.283 114.753 80.866  1.00 93.28  ?  207 VAL R CG1 1 
ATOM   8108 C CG2 . VAL E 5 207 ? 118.441 113.368 79.131  1.00 93.28  ?  207 VAL R CG2 1 
ATOM   8109 N N   . VAL E 5 208 ? 116.113 111.969 82.632  1.00 93.60  ?  208 VAL R N   1 
ATOM   8110 C CA  . VAL E 5 208 ? 115.190 112.010 83.762  1.00 93.60  ?  208 VAL R CA  1 
ATOM   8111 C C   . VAL E 5 208 ? 115.358 110.816 84.693  1.00 93.60  ?  208 VAL R C   1 
ATOM   8112 O O   . VAL E 5 208 ? 114.875 110.858 85.832  1.00 93.60  ?  208 VAL R O   1 
ATOM   8113 C CB  . VAL E 5 208 ? 113.733 112.081 83.272  1.00 93.60  ?  208 VAL R CB  1 
ATOM   8114 C CG1 . VAL E 5 208 ? 113.533 113.296 82.376  1.00 93.60  ?  208 VAL R CG1 1 
ATOM   8115 C CG2 . VAL E 5 208 ? 113.343 110.800 82.548  1.00 93.60  ?  208 VAL R CG2 1 
ATOM   8116 N N   . GLY E 5 209 ? 116.024 109.755 84.246  1.00 92.87  ?  209 GLY R N   1 
ATOM   8117 C CA  . GLY E 5 209 ? 116.177 108.563 85.058  1.00 92.87  ?  209 GLY R CA  1 
ATOM   8118 C C   . GLY E 5 209 ? 117.492 108.503 85.808  1.00 92.87  ?  209 GLY R C   1 
ATOM   8119 O O   . GLY E 5 209 ? 117.560 107.926 86.898  1.00 92.87  ?  209 GLY R O   1 
ATOM   8120 N N   . CYS E 5 210 ? 118.543 109.088 85.237  1.00 94.31  ?  210 CYS R N   1 
ATOM   8121 C CA  . CYS E 5 210 ? 119.878 109.042 85.823  1.00 94.31  ?  210 CYS R CA  1 
ATOM   8122 C C   . CYS E 5 210 ? 120.424 110.420 86.157  1.00 94.31  ?  210 CYS R C   1 
ATOM   8123 O O   . CYS E 5 210 ? 120.925 110.630 87.268  1.00 94.31  ?  210 CYS R O   1 
ATOM   8124 C CB  . CYS E 5 210 ? 120.840 108.321 84.866  1.00 94.31  ?  210 CYS R CB  1 
ATOM   8125 S SG  . CYS E 5 210 ? 122.523 108.136 85.501  1.00 94.31  ?  210 CYS R SG  1 
ATOM   8126 N N   . LEU E 5 211 ? 120.341 111.373 85.226  1.00 95.26  ?  211 LEU R N   1 
ATOM   8127 C CA  . LEU E 5 211 ? 120.952 112.679 85.451  1.00 95.26  ?  211 LEU R CA  1 
ATOM   8128 C C   . LEU E 5 211 ? 120.144 113.507 86.443  1.00 95.26  ?  211 LEU R C   1 
ATOM   8129 O O   . LEU E 5 211 ? 120.677 113.969 87.458  1.00 95.26  ?  211 LEU R O   1 
ATOM   8130 C CB  . LEU E 5 211 ? 121.101 113.422 84.122  1.00 95.26  ?  211 LEU R CB  1 
ATOM   8131 C CG  . LEU E 5 211 ? 122.170 112.877 83.170  1.00 95.26  ?  211 LEU R CG  1 
ATOM   8132 C CD1 . LEU E 5 211 ? 122.116 113.601 81.834  1.00 95.26  ?  211 LEU R CD1 1 
ATOM   8133 C CD2 . LEU E 5 211 ? 123.558 112.993 83.784  1.00 95.26  ?  211 LEU R CD2 1 
ATOM   8134 N N   . LEU E 5 212 ? 118.856 113.713 86.165  1.00 96.33  ?  212 LEU R N   1 
ATOM   8135 C CA  . LEU E 5 212 ? 118.043 114.550 87.045  1.00 96.33  ?  212 LEU R CA  1 
ATOM   8136 C C   . LEU E 5 212 ? 117.928 113.970 88.448  1.00 96.33  ?  212 LEU R C   1 
ATOM   8137 O O   . LEU E 5 212 ? 118.098 114.727 89.421  1.00 96.33  ?  212 LEU R O   1 
ATOM   8138 C CB  . LEU E 5 212 ? 116.666 114.773 86.412  1.00 96.33  ?  212 LEU R CB  1 
ATOM   8139 C CG  . LEU E 5 212 ? 115.611 115.447 87.293  1.00 96.33  ?  212 LEU R CG  1 
ATOM   8140 C CD1 . LEU E 5 212 ? 116.094 116.807 87.771  1.00 96.33  ?  212 LEU R CD1 1 
ATOM   8141 C CD2 . LEU E 5 212 ? 114.296 115.578 86.541  1.00 96.33  ?  212 LEU R CD2 1 
ATOM   8142 N N   . PRO E 5 213 ? 117.638 112.679 88.636  1.00 96.27  ?  213 PRO R N   1 
ATOM   8143 C CA  . PRO E 5 213 ? 117.617 112.144 90.008  1.00 96.27  ?  213 PRO R CA  1 
ATOM   8144 C C   . PRO E 5 213 ? 118.962 112.249 90.703  1.00 96.27  ?  213 PRO R C   1 
ATOM   8145 O O   . PRO E 5 213 ? 119.012 112.516 91.909  1.00 96.27  ?  213 PRO R O   1 
ATOM   8146 C CB  . PRO E 5 213 ? 117.187 110.683 89.809  1.00 96.27  ?  213 PRO R CB  1 
ATOM   8147 C CG  . PRO E 5 213 ? 116.507 110.658 88.486  1.00 96.27  ?  213 PRO R CG  1 
ATOM   8148 C CD  . PRO E 5 213 ? 117.231 111.663 87.651  1.00 96.27  ?  213 PRO R CD  1 
ATOM   8149 N N   . PHE E 5 214 ? 120.060 112.043 89.974  1.00 95.49  ?  214 PHE R N   1 
ATOM   8150 C CA  . PHE E 5 214 ? 121.381 112.160 90.582  1.00 95.49  ?  214 PHE R CA  1 
ATOM   8151 C C   . PHE E 5 214 ? 121.639 113.584 91.057  1.00 95.49  ?  214 PHE R C   1 
ATOM   8152 O O   . PHE E 5 214 ? 122.133 113.800 92.169  1.00 95.49  ?  214 PHE R O   1 
ATOM   8153 C CB  . PHE E 5 214 ? 122.457 111.722 89.589  1.00 95.49  ?  214 PHE R CB  1 
ATOM   8154 C CG  . PHE E 5 214 ? 123.859 111.957 90.075  1.00 95.49  ?  214 PHE R CG  1 
ATOM   8155 C CD1 . PHE E 5 214 ? 124.454 111.080 90.966  1.00 95.49  ?  214 PHE R CD1 1 
ATOM   8156 C CD2 . PHE E 5 214 ? 124.581 113.057 89.642  1.00 95.49  ?  214 PHE R CD2 1 
ATOM   8157 C CE1 . PHE E 5 214 ? 125.743 111.295 91.416  1.00 95.49  ?  214 PHE R CE1 1 
ATOM   8158 C CE2 . PHE E 5 214 ? 125.871 113.276 90.088  1.00 95.49  ?  214 PHE R CE2 1 
ATOM   8159 C CZ  . PHE E 5 214 ? 126.452 112.394 90.976  1.00 95.49  ?  214 PHE R CZ  1 
ATOM   8160 N N   . PHE E 5 215 ? 121.315 114.572 90.220  1.00 96.17  ?  215 PHE R N   1 
ATOM   8161 C CA  . PHE E 5 215 ? 121.496 115.963 90.624  1.00 96.17  ?  215 PHE R CA  1 
ATOM   8162 C C   . PHE E 5 215 ? 120.604 116.308 91.809  1.00 96.17  ?  215 PHE R C   1 
ATOM   8163 O O   . PHE E 5 215 ? 121.018 117.042 92.714  1.00 96.17  ?  215 PHE R O   1 
ATOM   8164 C CB  . PHE E 5 215 ? 121.211 116.898 89.448  1.00 96.17  ?  215 PHE R CB  1 
ATOM   8165 C CG  . PHE E 5 215 ? 122.323 116.959 88.437  1.00 96.17  ?  215 PHE R CG  1 
ATOM   8166 C CD1 . PHE E 5 215 ? 123.536 117.545 88.758  1.00 96.17  ?  215 PHE R CD1 1 
ATOM   8167 C CD2 . PHE E 5 215 ? 122.152 116.442 87.165  1.00 96.17  ?  215 PHE R CD2 1 
ATOM   8168 C CE1 . PHE E 5 215 ? 124.560 117.604 87.832  1.00 96.17  ?  215 PHE R CE1 1 
ATOM   8169 C CE2 . PHE E 5 215 ? 123.171 116.499 86.234  1.00 96.17  ?  215 PHE R CE2 1 
ATOM   8170 C CZ  . PHE E 5 215 ? 124.377 117.082 86.568  1.00 96.17  ?  215 PHE R CZ  1 
ATOM   8171 N N   . THR E 5 216 ? 119.373 115.791 91.822  1.00 96.10  ?  216 THR R N   1 
ATOM   8172 C CA  . THR E 5 216 ? 118.485 116.036 92.953  1.00 96.10  ?  216 THR R CA  1 
ATOM   8173 C C   . THR E 5 216 ? 119.077 115.471 94.239  1.00 96.10  ?  216 THR R C   1 
ATOM   8174 O O   . THR E 5 216 ? 119.136 116.159 95.266  1.00 96.10  ?  216 THR R O   1 
ATOM   8175 C CB  . THR E 5 216 ? 117.109 115.426 92.681  1.00 96.10  ?  216 THR R CB  1 
ATOM   8176 O OG1 . THR E 5 216 ? 116.569 115.975 91.472  1.00 96.10  ?  216 THR R OG1 1 
ATOM   8177 C CG2 . THR E 5 216 ? 116.156 115.713 93.835  1.00 96.10  ?  216 THR R CG2 1 
ATOM   8178 N N   . LEU E 5 217 ? 119.509 114.208 94.202  1.00 95.31  ?  217 LEU R N   1 
ATOM   8179 C CA  . LEU E 5 217 ? 120.158 113.607 95.363  1.00 95.31  ?  217 LEU R CA  1 
ATOM   8180 C C   . LEU E 5 217 ? 121.346 114.443 95.818  1.00 95.31  ?  217 LEU R C   1 
ATOM   8181 O O   . LEU E 5 217 ? 121.489 114.740 97.011  1.00 95.31  ?  217 LEU R O   1 
ATOM   8182 C CB  . LEU E 5 217 ? 120.616 112.185 95.032  1.00 95.31  ?  217 LEU R CB  1 
ATOM   8183 C CG  . LEU E 5 217 ? 119.543 111.145 94.703  1.00 95.31  ?  217 LEU R CG  1 
ATOM   8184 C CD1 . LEU E 5 217 ? 120.180 109.873 94.167  1.00 95.31  ?  217 LEU R CD1 1 
ATOM   8185 C CD2 . LEU E 5 217 ? 118.703 110.841 95.924  1.00 95.31  ?  217 LEU R CD2 1 
ATOM   8186 N N   . SER E 5 218 ? 122.213 114.826 94.878  1.00 94.35  ?  218 SER R N   1 
ATOM   8187 C CA  . SER E 5 218 ? 123.417 115.567 95.233  1.00 94.35  ?  218 SER R CA  1 
ATOM   8188 C C   . SER E 5 218 ? 123.069 116.883 95.912  1.00 94.35  ?  218 SER R C   1 
ATOM   8189 O O   . SER E 5 218 ? 123.596 117.198 96.983  1.00 94.35  ?  218 SER R O   1 
ATOM   8190 C CB  . SER E 5 218 ? 124.264 115.814 93.984  1.00 94.35  ?  218 SER R CB  1 
ATOM   8191 O OG  . SER E 5 218 ? 124.655 114.591 93.384  1.00 94.35  ?  218 SER R OG  1 
ATOM   8192 N N   . ILE E 5 219 ? 122.181 117.669 95.301  1.00 94.75  ?  219 ILE R N   1 
ATOM   8193 C CA  . ILE E 5 219 ? 121.827 118.971 95.863  1.00 94.75  ?  219 ILE R CA  1 
ATOM   8194 C C   . ILE E 5 219 ? 121.199 118.798 97.241  1.00 94.75  ?  219 ILE R C   1 
ATOM   8195 O O   . ILE E 5 219 ? 121.581 119.467 98.210  1.00 94.75  ?  219 ILE R O   1 
ATOM   8196 C CB  . ILE E 5 219 ? 120.891 119.733 94.908  1.00 94.75  ?  219 ILE R CB  1 
ATOM   8197 C CG1 . ILE E 5 219 ? 121.612 120.032 93.590  1.00 94.75  ?  219 ILE R CG1 1 
ATOM   8198 C CG2 . ILE E 5 219 ? 120.403 121.024 95.559  1.00 94.75  ?  219 ILE R CG2 1 
ATOM   8199 C CD1 . ILE E 5 219 ? 120.710 120.579 92.501  1.00 94.75  ?  219 ILE R CD1 1 
ATOM   8200 N N   . CYS E 5 220 ? 120.216 117.897 97.346  1.00 92.16  ?  220 CYS R N   1 
ATOM   8201 C CA  . CYS E 5 220 ? 119.519 117.711 98.613  1.00 92.16  ?  220 CYS R CA  1 
ATOM   8202 C C   . CYS E 5 220 ? 120.481 117.310 99.723  1.00 92.16  ?  220 CYS R C   1 
ATOM   8203 O O   . CYS E 5 220 ? 120.468 117.900 100.810 1.00 92.16  ?  220 CYS R O   1 
ATOM   8204 C CB  . CYS E 5 220 ? 118.420 116.658 98.453  1.00 92.16  ?  220 CYS R CB  1 
ATOM   8205 S SG  . CYS E 5 220 ? 117.024 117.191 97.436  1.00 92.16  ?  220 CYS R SG  1 
ATOM   8206 N N   . TYR E 5 221 ? 121.333 116.318 99.471  1.00 91.96  ?  221 TYR R N   1 
ATOM   8207 C CA  . TYR E 5 221 ? 122.225 115.838 100.517 1.00 91.96  ?  221 TYR R CA  1 
ATOM   8208 C C   . TYR E 5 221 ? 123.368 116.801 100.803 1.00 91.96  ?  221 TYR R C   1 
ATOM   8209 O O   . TYR E 5 221 ? 123.844 116.855 101.941 1.00 91.96  ?  221 TYR R O   1 
ATOM   8210 C CB  . TYR E 5 221 ? 122.777 114.457 100.148 1.00 91.96  ?  221 TYR R CB  1 
ATOM   8211 C CG  . TYR E 5 221 ? 121.737 113.349 100.179 1.00 91.96  ?  221 TYR R CG  1 
ATOM   8212 C CD1 . TYR E 5 221 ? 122.093 112.030 99.936  1.00 91.96  ?  221 TYR R CD1 1 
ATOM   8213 C CD2 . TYR E 5 221 ? 120.400 113.623 100.447 1.00 91.96  ?  221 TYR R CD2 1 
ATOM   8214 C CE1 . TYR E 5 221 ? 121.152 111.017 99.962  1.00 91.96  ?  221 TYR R CE1 1 
ATOM   8215 C CE2 . TYR E 5 221 ? 119.455 112.618 100.475 1.00 91.96  ?  221 TYR R CE2 1 
ATOM   8216 C CZ  . TYR E 5 221 ? 119.835 111.318 100.230 1.00 91.96  ?  221 TYR R CZ  1 
ATOM   8217 O OH  . TYR E 5 221 ? 118.896 110.313 100.257 1.00 91.96  ?  221 TYR R OH  1 
ATOM   8218 N N   . LEU E 5 222 ? 123.799 117.596 99.821  1.00 93.36  ?  222 LEU R N   1 
ATOM   8219 C CA  . LEU E 5 222 ? 124.782 118.636 100.102 1.00 93.36  ?  222 LEU R CA  1 
ATOM   8220 C C   . LEU E 5 222 ? 124.185 119.707 101.004 1.00 93.36  ?  222 LEU R C   1 
ATOM   8221 O O   . LEU E 5 222 ? 124.840 120.192 101.933 1.00 93.36  ?  222 LEU R O   1 
ATOM   8222 C CB  . LEU E 5 222 ? 125.288 119.247 98.794  1.00 93.36  ?  222 LEU R CB  1 
ATOM   8223 C CG  . LEU E 5 222 ? 126.222 118.368 97.958  1.00 93.36  ?  222 LEU R CG  1 
ATOM   8224 C CD1 . LEU E 5 222 ? 126.460 118.989 96.591  1.00 93.36  ?  222 LEU R CD1 1 
ATOM   8225 C CD2 . LEU E 5 222 ? 127.542 118.140 98.677  1.00 93.36  ?  222 LEU R CD2 1 
ATOM   8226 N N   . LEU E 5 223 ? 122.929 120.084 100.751 1.00 91.18  ?  223 LEU R N   1 
ATOM   8227 C CA  . LEU E 5 223 ? 122.263 121.032 101.638 1.00 91.18  ?  223 LEU R CA  1 
ATOM   8228 C C   . LEU E 5 223 ? 122.071 120.437 103.029 1.00 91.18  ?  223 LEU R C   1 
ATOM   8229 O O   . LEU E 5 223 ? 122.205 121.142 104.037 1.00 91.18  ?  223 LEU R O   1 
ATOM   8230 C CB  . LEU E 5 223 ? 120.923 121.457 101.037 1.00 91.18  ?  223 LEU R CB  1 
ATOM   8231 C CG  . LEU E 5 223 ? 121.024 122.266 99.741  1.00 91.18  ?  223 LEU R CG  1 
ATOM   8232 C CD1 . LEU E 5 223 ? 119.647 122.521 99.149  1.00 91.18  ?  223 LEU R CD1 1 
ATOM   8233 C CD2 . LEU E 5 223 ? 121.757 123.579 99.981  1.00 91.18  ?  223 LEU R CD2 1 
ATOM   8234 N N   . ILE E 5 224 ? 121.769 119.139 103.104 1.00 87.47  ?  224 ILE R N   1 
ATOM   8235 C CA  . ILE E 5 224 ? 121.643 118.482 104.404 1.00 87.47  ?  224 ILE R CA  1 
ATOM   8236 C C   . ILE E 5 224 ? 122.971 118.521 105.150 1.00 87.47  ?  224 ILE R C   1 
ATOM   8237 O O   . ILE E 5 224 ? 123.015 118.788 106.357 1.00 87.47  ?  224 ILE R O   1 
ATOM   8238 C CB  . ILE E 5 224 ? 121.141 117.037 104.227 1.00 87.47  ?  224 ILE R CB  1 
ATOM   8239 C CG1 . ILE E 5 224 ? 119.684 117.032 103.757 1.00 87.47  ?  224 ILE R CG1 1 
ATOM   8240 C CG2 . ILE E 5 224 ? 121.289 116.260 105.531 1.00 87.47  ?  224 ILE R CG2 1 
ATOM   8241 C CD1 . ILE E 5 224 ? 119.187 115.668 103.319 1.00 87.47  ?  224 ILE R CD1 1 
ATOM   8242 N N   . ILE E 5 225 ? 124.072 118.247 104.448 1.00 87.59  ?  225 ILE R N   1 
ATOM   8243 C CA  . ILE E 5 225 ? 125.386 118.279 105.082 1.00 87.59  ?  225 ILE R CA  1 
ATOM   8244 C C   . ILE E 5 225 ? 125.718 119.692 105.544 1.00 87.59  ?  225 ILE R C   1 
ATOM   8245 O O   . ILE E 5 225 ? 126.306 119.888 106.614 1.00 87.59  ?  225 ILE R O   1 
ATOM   8246 C CB  . ILE E 5 225 ? 126.455 117.734 104.117 1.00 87.59  ?  225 ILE R CB  1 
ATOM   8247 C CG1 . ILE E 5 225 ? 126.218 116.247 103.835 1.00 87.59  ?  225 ILE R CG1 1 
ATOM   8248 C CG2 . ILE E 5 225 ? 127.849 117.953 104.687 1.00 87.59  ?  225 ILE R CG2 1 
ATOM   8249 C CD1 . ILE E 5 225 ? 126.615 115.330 104.972 1.00 87.59  ?  225 ILE R CD1 1 
ATOM   8250 N N   . ARG E 5 226 ? 125.358 120.697 104.743 1.00 89.25  ?  226 ARG R N   1 
ATOM   8251 C CA  . ARG E 5 226 ? 125.581 122.079 105.154 1.00 89.25  ?  226 ARG R CA  1 
ATOM   8252 C C   . ARG E 5 226 ? 124.808 122.400 106.427 1.00 89.25  ?  226 ARG R C   1 
ATOM   8253 O O   . ARG E 5 226 ? 125.350 123.009 107.357 1.00 89.25  ?  226 ARG R O   1 
ATOM   8254 C CB  . ARG E 5 226 ? 125.176 123.034 104.031 1.00 89.25  ?  226 ARG R CB  1 
ATOM   8255 C CG  . ARG E 5 226 ? 125.571 124.484 104.277 1.00 89.25  ?  226 ARG R CG  1 
ATOM   8256 C CD  . ARG E 5 226 ? 124.729 125.443 103.452 1.00 89.25  ?  226 ARG R CD  1 
ATOM   8257 N NE  . ARG E 5 226 ? 124.840 125.190 102.018 1.00 89.25  ?  226 ARG R NE  1 
ATOM   8258 C CZ  . ARG E 5 226 ? 124.206 125.892 101.084 1.00 89.25  ?  226 ARG R CZ  1 
ATOM   8259 N NH1 . ARG E 5 226 ? 124.367 125.590 99.803  1.00 89.25  1  226 ARG R NH1 1 
ATOM   8260 N NH2 . ARG E 5 226 ? 123.411 126.898 101.426 1.00 89.25  ?  226 ARG R NH2 1 
ATOM   8261 N N   . VAL E 5 227 ? 123.538 121.996 106.486 1.00 85.12  ?  227 VAL R N   1 
ATOM   8262 C CA  . VAL E 5 227 ? 122.736 122.255 107.678 1.00 85.12  ?  227 VAL R CA  1 
ATOM   8263 C C   . VAL E 5 227 ? 123.322 121.531 108.884 1.00 85.12  ?  227 VAL R C   1 
ATOM   8264 O O   . VAL E 5 227 ? 123.326 122.061 110.002 1.00 85.12  ?  227 VAL R O   1 
ATOM   8265 C CB  . VAL E 5 227 ? 121.270 121.853 107.432 1.00 85.12  ?  227 VAL R CB  1 
ATOM   8266 C CG1 . VAL E 5 227 ? 120.483 121.886 108.734 1.00 85.12  ?  227 VAL R CG1 1 
ATOM   8267 C CG2 . VAL E 5 227 ? 120.636 122.775 106.401 1.00 85.12  ?  227 VAL R CG2 1 
ATOM   8268 N N   . LEU E 5 228 ? 123.822 120.309 108.683 1.00 83.46  ?  228 LEU R N   1 
ATOM   8269 C CA  . LEU E 5 228 ? 124.415 119.566 109.790 1.00 83.46  ?  228 LEU R CA  1 
ATOM   8270 C C   . LEU E 5 228 ? 125.691 120.230 110.290 1.00 83.46  ?  228 LEU R C   1 
ATOM   8271 O O   . LEU E 5 228 ? 125.917 120.304 111.503 1.00 83.46  ?  228 LEU R O   1 
ATOM   8272 C CB  . LEU E 5 228 ? 124.703 118.125 109.364 1.00 83.46  ?  228 LEU R CB  1 
ATOM   8273 C CG  . LEU E 5 228 ? 123.488 117.227 109.118 1.00 83.46  ?  228 LEU R CG  1 
ATOM   8274 C CD1 . LEU E 5 228 ? 123.926 115.891 108.542 1.00 83.46  ?  228 LEU R CD1 1 
ATOM   8275 C CD2 . LEU E 5 228 ? 122.691 117.021 110.398 1.00 83.46  ?  228 LEU R CD2 1 
ATOM   8276 N N   . LEU E 5 229 ? 126.533 120.716 109.381 1.00 85.63  ?  229 LEU R N   1 
ATOM   8277 C CA  . LEU E 5 229 ? 127.761 121.410 109.745 1.00 85.63  ?  229 LEU R CA  1 
ATOM   8278 C C   . LEU E 5 229 ? 127.523 122.873 110.102 1.00 85.63  ?  229 LEU R C   1 
ATOM   8279 O O   . LEU E 5 229 ? 128.485 123.595 110.382 1.00 85.63  ?  229 LEU R O   1 
ATOM   8280 C CB  . LEU E 5 229 ? 128.778 121.316 108.604 1.00 85.63  ?  229 LEU R CB  1 
ATOM   8281 C CG  . LEU E 5 229 ? 129.200 119.908 108.175 1.00 85.63  ?  229 LEU R CG  1 
ATOM   8282 C CD1 . LEU E 5 229 ? 130.140 119.978 106.980 1.00 85.63  ?  229 LEU R CD1 1 
ATOM   8283 C CD2 . LEU E 5 229 ? 129.855 119.156 109.324 1.00 85.63  ?  229 LEU R CD2 1 
ATOM   8284 N N   . LYS E 5 230 ? 126.266 123.324 110.092 1.00 83.79  ?  230 LYS R N   1 
ATOM   8285 C CA  . LYS E 5 230 ? 125.968 124.704 110.461 1.00 83.79  ?  230 LYS R CA  1 
ATOM   8286 C C   . LYS E 5 230 ? 126.426 125.023 111.878 1.00 83.79  ?  230 LYS R C   1 
ATOM   8287 O O   . LYS E 5 230 ? 126.672 126.192 112.198 1.00 83.79  ?  230 LYS R O   1 
ATOM   8288 C CB  . LYS E 5 230 ? 124.467 124.967 110.320 1.00 83.79  ?  230 LYS R CB  1 
ATOM   8289 C CG  . LYS E 5 230 ? 124.042 126.412 110.574 1.00 83.79  ?  230 LYS R CG  1 
ATOM   8290 C CD  . LYS E 5 230 ? 124.557 127.369 109.504 1.00 83.79  ?  230 LYS R CD  1 
ATOM   8291 C CE  . LYS E 5 230 ? 123.906 127.112 108.152 1.00 83.79  ?  230 LYS R CE  1 
ATOM   8292 N NZ  . LYS E 5 230 ? 124.306 128.124 107.135 1.00 83.79  1  230 LYS R NZ  1 
ATOM   8293 N N   . VAL E 5 231 ? 126.540 124.009 112.739 1.00 74.63  ?  231 VAL R N   1 
ATOM   8294 C CA  . VAL E 5 231 ? 126.938 124.239 114.123 1.00 74.63  ?  231 VAL R CA  1 
ATOM   8295 C C   . VAL E 5 231 ? 128.265 124.980 114.154 1.00 74.63  ?  231 VAL R C   1 
ATOM   8296 O O   . VAL E 5 231 ? 129.219 124.607 113.463 1.00 74.63  ?  231 VAL R O   1 
ATOM   8297 C CB  . VAL E 5 231 ? 127.017 122.903 114.884 1.00 74.63  ?  231 VAL R CB  1 
ATOM   8298 C CG1 . VAL E 5 231 ? 128.085 121.998 114.278 1.00 74.63  ?  231 VAL R CG1 1 
ATOM   8299 C CG2 . VAL E 5 231 ? 127.289 123.145 116.363 1.00 74.63  ?  231 VAL R CG2 1 
ATOM   8300 N N   . GLU E 5 232 ? 128.327 126.041 114.960 1.00 67.95  ?  232 GLU R N   1 
ATOM   8301 C CA  . GLU E 5 232 ? 129.540 126.836 115.099 1.00 67.95  ?  232 GLU R CA  1 
ATOM   8302 C C   . GLU E 5 232 ? 130.333 126.507 116.355 1.00 67.95  ?  232 GLU R C   1 
ATOM   8303 O O   . GLU E 5 232 ? 131.549 126.729 116.374 1.00 67.95  ?  232 GLU R O   1 
ATOM   8304 C CB  . GLU E 5 232 ? 129.200 128.333 115.111 1.00 67.95  ?  232 GLU R CB  1 
ATOM   8305 C CG  . GLU E 5 232 ? 128.468 128.829 113.871 1.00 67.95  ?  232 GLU R CG  1 
ATOM   8306 C CD  . GLU E 5 232 ? 126.991 128.484 113.880 1.00 67.95  ?  232 GLU R CD  1 
ATOM   8307 O OE1 . GLU E 5 232 ? 126.543 127.800 114.825 1.00 67.95  ?  232 GLU R OE1 1 
ATOM   8308 O OE2 . GLU E 5 232 ? 126.277 128.896 112.942 1.00 67.95  ?  232 GLU R OE2 1 
ATOM   8309 N N   . VAL E 5 233 ? 129.684 125.990 117.394 1.00 65.86  ?  233 VAL R N   1 
ATOM   8310 C CA  . VAL E 5 233 ? 130.368 125.662 118.638 1.00 65.86  ?  233 VAL R CA  1 
ATOM   8311 C C   . VAL E 5 233 ? 129.720 124.442 119.282 1.00 65.86  ?  233 VAL R C   1 
ATOM   8312 O O   . VAL E 5 233 ? 128.525 124.201 119.114 1.00 65.86  ?  233 VAL R O   1 
ATOM   8313 C CB  . VAL E 5 233 ? 130.362 126.859 119.608 1.00 65.86  ?  233 VAL R CB  1 
ATOM   8314 C CG1 . VAL E 5 233 ? 128.938 127.191 120.043 1.00 65.86  ?  233 VAL R CG1 1 
ATOM   8315 C CG2 . VAL E 5 233 ? 131.249 126.574 120.814 1.00 65.86  ?  233 VAL R CG2 1 
ATOM   8316 N N   . ARG E 5 239 ? 129.556 116.402 117.375 1.00 80.50  ?  239 ARG R N   1 
ATOM   8317 C CA  . ARG E 5 239 ? 128.393 115.936 118.119 1.00 80.50  ?  239 ARG R CA  1 
ATOM   8318 C C   . ARG E 5 239 ? 128.128 114.462 117.825 1.00 80.50  ?  239 ARG R C   1 
ATOM   8319 O O   . ARG E 5 239 ? 128.243 114.018 116.683 1.00 80.50  ?  239 ARG R O   1 
ATOM   8320 C CB  . ARG E 5 239 ? 127.162 116.776 117.770 1.00 80.50  ?  239 ARG R CB  1 
ATOM   8321 C CG  . ARG E 5 239 ? 125.938 116.473 118.620 1.00 80.50  ?  239 ARG R CG  1 
ATOM   8322 C CD  . ARG E 5 239 ? 124.730 117.273 118.158 1.00 80.50  ?  239 ARG R CD  1 
ATOM   8323 N NE  . ARG E 5 239 ? 124.968 118.712 118.212 1.00 80.50  ?  239 ARG R NE  1 
ATOM   8324 C CZ  . ARG E 5 239 ? 124.085 119.633 117.836 1.00 80.50  ?  239 ARG R CZ  1 
ATOM   8325 N NH1 . ARG E 5 239 ? 122.895 119.271 117.374 1.00 80.50  1  239 ARG R NH1 1 
ATOM   8326 N NH2 . ARG E 5 239 ? 124.393 120.920 117.922 1.00 80.50  ?  239 ARG R NH2 1 
ATOM   8327 N N   . VAL E 5 240 ? 127.773 113.706 118.866 1.00 82.92  ?  240 VAL R N   1 
ATOM   8328 C CA  . VAL E 5 240 ? 127.521 112.278 118.695 1.00 82.92  ?  240 VAL R CA  1 
ATOM   8329 C C   . VAL E 5 240 ? 126.333 112.055 117.769 1.00 82.92  ?  240 VAL R C   1 
ATOM   8330 O O   . VAL E 5 240 ? 126.350 111.159 116.916 1.00 82.92  ?  240 VAL R O   1 
ATOM   8331 C CB  . VAL E 5 240 ? 127.308 111.607 120.065 1.00 82.92  ?  240 VAL R CB  1 
ATOM   8332 C CG1 . VAL E 5 240 ? 127.010 110.125 119.892 1.00 82.92  ?  240 VAL R CG1 1 
ATOM   8333 C CG2 . VAL E 5 240 ? 128.529 111.811 120.951 1.00 82.92  ?  240 VAL R CG2 1 
ATOM   8334 N N   . SER E 5 241 ? 125.312 112.889 117.634 1.00 82.27  ?  241 SER R N   1 
ATOM   8335 C CA  . SER E 5 241 ? 124.275 112.661 116.557 1.00 82.27  ?  241 SER R CA  1 
ATOM   8336 C C   . SER E 5 241 ? 124.717 113.029 115.090 1.00 82.27  ?  241 SER R C   1 
ATOM   8337 O O   . SER E 5 241 ? 124.553 112.241 114.067 1.00 82.27  ?  241 SER R O   1 
ATOM   8338 C CB  . SER E 5 241 ? 123.024 113.460 116.896 1.00 82.27  ?  241 SER R CB  1 
ATOM   8339 O OG  . SER E 5 241 ? 122.758 113.419 118.285 1.00 82.27  ?  241 SER R OG  1 
ATOM   8340 N N   . HIS E 5 242 ? 125.311 114.210 114.954 1.00 86.17  ?  242 HIS R N   1 
ATOM   8341 C CA  . HIS E 5 242 ? 125.687 114.703 113.613 1.00 86.17  ?  242 HIS R CA  1 
ATOM   8342 C C   . HIS E 5 242 ? 126.696 113.867 112.843 1.00 86.17  ?  242 HIS R C   1 
ATOM   8343 O O   . HIS E 5 242 ? 126.611 113.791 111.633 1.00 86.17  ?  242 HIS R O   1 
ATOM   8344 C CB  . HIS E 5 242 ? 126.193 116.149 113.691 1.00 86.17  ?  242 HIS R CB  1 
ATOM   8345 C CG  . HIS E 5 242 ? 125.127 117.154 114.011 1.00 86.17  ?  242 HIS R CG  1 
ATOM   8346 N ND1 . HIS E 5 242 ? 125.402 118.495 114.167 1.00 86.17  ?  242 HIS R ND1 1 
ATOM   8347 C CD2 . HIS E 5 242 ? 123.791 117.021 114.194 1.00 86.17  ?  242 HIS R CD2 1 
ATOM   8348 C CE1 . HIS E 5 242 ? 124.284 119.144 114.434 1.00 86.17  ?  242 HIS R CE1 1 
ATOM   8349 N NE2 . HIS E 5 242 ? 123.292 118.273 114.457 1.00 86.17  ?  242 HIS R NE2 1 
ATOM   8350 N N   . ARG E 5 243 ? 127.630 113.232 113.549 1.00 88.50  ?  243 ARG R N   1 
ATOM   8351 C CA  . ARG E 5 243 ? 128.659 112.414 112.907 1.00 88.50  ?  243 ARG R CA  1 
ATOM   8352 C C   . ARG E 5 243 ? 128.031 111.187 112.269 1.00 88.50  ?  243 ARG R C   1 
ATOM   8353 O O   . ARG E 5 243 ? 128.389 110.799 111.152 1.00 88.50  ?  243 ARG R O   1 
ATOM   8354 C CB  . ARG E 5 243 ? 129.690 111.997 113.957 1.00 88.50  ?  243 ARG R CB  1 
ATOM   8355 C CG  . ARG E 5 243 ? 130.974 111.382 113.424 1.00 88.50  ?  243 ARG R CG  1 
ATOM   8356 C CD  . ARG E 5 243 ? 131.802 110.744 114.538 1.00 88.50  ?  243 ARG R CD  1 
ATOM   8357 N NE  . ARG E 5 243 ? 131.518 111.289 115.874 1.00 88.50  ?  243 ARG R NE  1 
ATOM   8358 C CZ  . ARG E 5 243 ? 131.960 112.454 116.365 1.00 88.50  ?  243 ARG R CZ  1 
ATOM   8359 N NH1 . ARG E 5 243 ? 131.610 112.818 117.602 1.00 88.50  1  243 ARG R NH1 1 
ATOM   8360 N NH2 . ARG E 5 243 ? 132.728 113.275 115.639 1.00 88.50  ?  243 ARG R NH2 1 
ATOM   8361 N N   . LYS E 5 244 ? 127.108 110.554 112.983 1.00 90.06  ?  244 LYS R N   1 
ATOM   8362 C CA  . LYS E 5 244 ? 126.414 109.408 112.414 1.00 90.06  ?  244 LYS R CA  1 
ATOM   8363 C C   . LYS E 5 244 ? 125.590 109.850 111.216 1.00 90.06  ?  244 LYS R C   1 
ATOM   8364 O O   . LYS E 5 244 ? 125.558 109.172 110.206 1.00 90.06  ?  244 LYS R O   1 
ATOM   8365 C CB  . LYS E 5 244 ? 125.530 108.709 113.444 1.00 90.06  ?  244 LYS R CB  1 
ATOM   8366 C CG  . LYS E 5 244 ? 124.965 107.398 112.928 1.00 90.06  ?  244 LYS R CG  1 
ATOM   8367 C CD  . LYS E 5 244 ? 124.304 106.569 114.012 1.00 90.06  ?  244 LYS R CD  1 
ATOM   8368 C CE  . LYS E 5 244 ? 124.297 105.103 113.614 1.00 90.06  ?  244 LYS R CE  1 
ATOM   8369 N NZ  . LYS E 5 244 ? 123.228 104.334 114.293 1.00 90.06  1  244 LYS R NZ  1 
ATOM   8370 N N   . ALA E 5 245 ? 124.937 111.000 111.318 1.00 91.17  ?  245 ALA R N   1 
ATOM   8371 C CA  . ALA E 5 245 ? 124.177 111.515 110.185 1.00 91.17  ?  245 ALA R CA  1 
ATOM   8372 C C   . ALA E 5 245 ? 125.106 111.785 109.031 1.00 91.17  ?  245 ALA R C   1 
ATOM   8373 O O   . ALA E 5 245 ? 124.784 111.470 107.897 1.00 91.17  ?  245 ALA R O   1 
ATOM   8374 C CB  . ALA E 5 245 ? 123.395 112.767 110.564 1.00 91.17  ?  245 ALA R CB  1 
ATOM   8375 N N   . LEU E 5 246 ? 126.279 112.321 109.324 1.00 92.47  ?  246 LEU R N   1 
ATOM   8376 C CA  . LEU E 5 246 ? 127.256 112.618 108.290 1.00 92.47  ?  246 LEU R CA  1 
ATOM   8377 C C   . LEU E 5 246 ? 127.677 111.339 107.570 1.00 92.47  ?  246 LEU R C   1 
ATOM   8378 O O   . LEU E 5 246 ? 127.781 111.335 106.340 1.00 92.47  ?  246 LEU R O   1 
ATOM   8379 C CB  . LEU E 5 246 ? 128.472 113.316 108.923 1.00 92.47  ?  246 LEU R CB  1 
ATOM   8380 C CG  . LEU E 5 246 ? 129.733 113.632 108.119 1.00 92.47  ?  246 LEU R CG  1 
ATOM   8381 C CD1 . LEU E 5 246 ? 129.412 114.524 106.939 1.00 92.47  ?  246 LEU R CD1 1 
ATOM   8382 C CD2 . LEU E 5 246 ? 130.778 114.284 109.014 1.00 92.47  ?  246 LEU R CD2 1 
ATOM   8383 N N   . THR E 5 247 ? 127.887 110.252 108.316 1.00 92.94  ?  247 THR R N   1 
ATOM   8384 C CA  . THR E 5 247 ? 128.359 109.012 107.684 1.00 92.94  ?  247 THR R CA  1 
ATOM   8385 C C   . THR E 5 247 ? 127.219 108.359 106.895 1.00 92.94  ?  247 THR R C   1 
ATOM   8386 O O   . THR E 5 247 ? 127.472 107.768 105.852 1.00 92.94  ?  247 THR R O   1 
ATOM   8387 C CB  . THR E 5 247 ? 129.042 108.028 108.674 1.00 92.94  ?  247 THR R CB  1 
ATOM   8388 O OG1 . THR E 5 247 ? 129.646 106.962 107.929 1.00 92.94  ?  247 THR R OG1 1 
ATOM   8389 C CG2 . THR E 5 247 ? 128.071 107.433 109.700 1.00 92.94  ?  247 THR R CG2 1 
ATOM   8390 N N   . THR E 5 248 ? 125.977 108.470 107.370 1.00 94.26  ?  248 THR R N   1 
ATOM   8391 C CA  . THR E 5 248 ? 124.822 107.945 106.626 1.00 94.26  ?  248 THR R CA  1 
ATOM   8392 C C   . THR E 5 248 ? 124.667 108.619 105.248 1.00 94.26  ?  248 THR R C   1 
ATOM   8393 O O   . THR E 5 248 ? 124.344 107.946 104.270 1.00 94.26  ?  248 THR R O   1 
ATOM   8394 C CB  . THR E 5 248 ? 123.502 108.090 107.430 1.00 94.26  ?  248 THR R CB  1 
ATOM   8395 O OG1 . THR E 5 248 ? 123.561 107.290 108.619 1.00 94.26  ?  248 THR R OG1 1 
ATOM   8396 C CG2 . THR E 5 248 ? 122.285 107.653 106.611 1.00 94.26  ?  248 THR R CG2 1 
ATOM   8397 N N   . ILE E 5 249 ? 124.885 109.933 105.164 1.00 94.32  ?  249 ILE R N   1 
ATOM   8398 C CA  . ILE E 5 249 ? 124.682 110.646 103.871 1.00 94.32  ?  249 ILE R CA  1 
ATOM   8399 C C   . ILE E 5 249 ? 125.719 110.432 102.735 1.00 94.32  ?  249 ILE R C   1 
ATOM   8400 O O   . ILE E 5 249 ? 125.331 110.422 101.599 1.00 94.32  ?  249 ILE R O   1 
ATOM   8401 C CB  . ILE E 5 249 ? 124.651 112.189 104.117 1.00 94.32  ?  249 ILE R CB  1 
ATOM   8402 C CG1 . ILE E 5 249 ? 123.547 112.655 105.099 1.00 94.32  ?  249 ILE R CG1 1 
ATOM   8403 C CG2 . ILE E 5 249 ? 124.531 112.975 102.818 1.00 94.32  ?  249 ILE R CG2 1 
ATOM   8404 C CD1 . ILE E 5 249 ? 122.290 111.821 105.196 1.00 94.32  ?  249 ILE R CD1 1 
ATOM   8405 N N   . ILE E 5 250 ? 127.007 110.293 103.001 1.00 94.51  ?  250 ILE R N   1 
ATOM   8406 C CA  . ILE E 5 250 ? 128.096 110.234 102.031 1.00 94.51  ?  250 ILE R CA  1 
ATOM   8407 C C   . ILE E 5 250 ? 128.264 108.816 101.501 1.00 94.51  ?  250 ILE R C   1 
ATOM   8408 O O   . ILE E 5 250 ? 128.583 108.612 100.323 1.00 94.51  ?  250 ILE R O   1 
ATOM   8409 C CB  . ILE E 5 250 ? 129.399 110.763 102.659 1.00 94.51  ?  250 ILE R CB  1 
ATOM   8410 C CG1 . ILE E 5 250 ? 129.204 112.202 103.150 1.00 94.51  ?  250 ILE R CG1 1 
ATOM   8411 C CG2 . ILE E 5 250 ? 130.542 110.687 101.651 1.00 94.51  ?  250 ILE R CG2 1 
ATOM   8412 C CD1 . ILE E 5 250 ? 130.391 112.763 103.901 1.00 94.51  ?  250 ILE R CD1 1 
ATOM   8413 N N   . ILE E 5 251 ? 128.065 107.812 102.360 1.00 95.29  ?  251 ILE R N   1 
ATOM   8414 C CA  . ILE E 5 251 ? 128.144 106.432 101.901 1.00 95.29  ?  251 ILE R CA  1 
ATOM   8415 C C   . ILE E 5 251 ? 127.092 106.157 100.837 1.00 95.29  ?  251 ILE R C   1 
ATOM   8416 O O   . ILE E 5 251 ? 127.386 105.499 99.831  1.00 95.29  ?  251 ILE R O   1 
ATOM   8417 C CB  . ILE E 5 251 ? 128.001 105.454 103.083 1.00 95.29  ?  251 ILE R CB  1 
ATOM   8418 C CG1 . ILE E 5 251 ? 128.314 104.026 102.630 1.00 95.29  ?  251 ILE R CG1 1 
ATOM   8419 C CG2 . ILE E 5 251 ? 126.602 105.521 103.669 1.00 95.29  ?  251 ILE R CG2 1 
ATOM   8420 C CD1 . ILE E 5 251 ? 128.384 103.025 103.765 1.00 95.29  ?  251 ILE R CD1 1 
ATOM   8421 N N   . THR E 5 252 ? 125.871 106.663 101.022 1.00 95.78  ?  252 THR R N   1 
ATOM   8422 C CA  . THR E 5 252 ? 124.846 106.524 99.996  1.00 95.78  ?  252 THR R CA  1 
ATOM   8423 C C   . THR E 5 252 ? 125.253 107.235 98.712  1.00 95.78  ?  252 THR R C   1 
ATOM   8424 O O   . THR E 5 252 ? 124.993 106.734 97.614  1.00 95.78  ?  252 THR R O   1 
ATOM   8425 C CB  . THR E 5 252 ? 123.510 107.071 100.502 1.00 95.78  ?  252 THR R CB  1 
ATOM   8426 O OG1 . THR E 5 252 ? 123.688 108.406 100.990 1.00 95.78  ?  252 THR R OG1 1 
ATOM   8427 C CG2 . THR E 5 252 ? 122.953 106.192 101.614 1.00 95.78  ?  252 THR R CG2 1 
ATOM   8428 N N   . LEU E 5 253 ? 125.899 108.399 98.828  1.00 95.63  ?  253 LEU R N   1 
ATOM   8429 C CA  . LEU E 5 253 ? 126.357 109.106 97.637  1.00 95.63  ?  253 LEU R CA  1 
ATOM   8430 C C   . LEU E 5 253 ? 127.383 108.292 96.863  1.00 95.63  ?  253 LEU R C   1 
ATOM   8431 O O   . LEU E 5 253 ? 127.288 108.184 95.635  1.00 95.63  ?  253 LEU R O   1 
ATOM   8432 C CB  . LEU E 5 253 ? 126.953 110.461 98.020  1.00 95.63  ?  253 LEU R CB  1 
ATOM   8433 C CG  . LEU E 5 253 ? 125.992 111.484 98.631  1.00 95.63  ?  253 LEU R CG  1 
ATOM   8434 C CD1 . LEU E 5 253 ? 126.736 112.728 99.100  1.00 95.63  ?  253 LEU R CD1 1 
ATOM   8435 C CD2 . LEU E 5 253 ? 124.913 111.845 97.631  1.00 95.63  ?  253 LEU R CD2 1 
ATOM   8436 N N   . ILE E 5 254 ? 128.364 107.713 97.556  1.00 95.63  ?  254 ILE R N   1 
ATOM   8437 C CA  . ILE E 5 254 ? 129.398 106.959 96.856  1.00 95.63  ?  254 ILE R CA  1 
ATOM   8438 C C   . ILE E 5 254 ? 128.851 105.636 96.332  1.00 95.63  ?  254 ILE R C   1 
ATOM   8439 O O   . ILE E 5 254 ? 129.360 105.102 95.340  1.00 95.63  ?  254 ILE R O   1 
ATOM   8440 C CB  . ILE E 5 254 ? 130.619 106.738 97.766  1.00 95.63  ?  254 ILE R CB  1 
ATOM   8441 C CG1 . ILE E 5 254 ? 130.234 105.911 98.993  1.00 95.63  ?  254 ILE R CG1 1 
ATOM   8442 C CG2 . ILE E 5 254 ? 131.210 108.075 98.189  1.00 95.63  ?  254 ILE R CG2 1 
ATOM   8443 C CD1 . ILE E 5 254 ? 131.386 105.638 99.936  1.00 95.63  ?  254 ILE R CD1 1 
ATOM   8444 N N   . ILE E 5 255 ? 127.816 105.083 96.974  1.00 95.94  ?  255 ILE R N   1 
ATOM   8445 C CA  . ILE E 5 255 ? 127.201 103.855 96.472  1.00 95.94  ?  255 ILE R CA  1 
ATOM   8446 C C   . ILE E 5 255 ? 126.271 104.108 95.298  1.00 95.94  ?  255 ILE R C   1 
ATOM   8447 O O   . ILE E 5 255 ? 126.097 103.219 94.455  1.00 95.94  ?  255 ILE R O   1 
ATOM   8448 C CB  . ILE E 5 255 ? 126.422 103.137 97.591  1.00 95.94  ?  255 ILE R CB  1 
ATOM   8449 C CG1 . ILE E 5 255 ? 127.380 102.637 98.680  1.00 95.94  ?  255 ILE R CG1 1 
ATOM   8450 C CG2 . ILE E 5 255 ? 125.609 101.982 97.022  1.00 95.94  ?  255 ILE R CG2 1 
ATOM   8451 C CD1 . ILE E 5 255 ? 128.304 101.513 98.241  1.00 95.94  ?  255 ILE R CD1 1 
ATOM   8452 N N   . PHE E 5 256 ? 125.673 105.295 95.212  1.00 95.65  ?  256 PHE R N   1 
ATOM   8453 C CA  . PHE E 5 256 ? 124.798 105.661 94.105  1.00 95.65  ?  256 PHE R CA  1 
ATOM   8454 C C   . PHE E 5 256 ? 125.567 106.170 92.895  1.00 95.65  ?  256 PHE R C   1 
ATOM   8455 O O   . PHE E 5 256 ? 125.147 105.939 91.757  1.00 95.65  ?  256 PHE R O   1 
ATOM   8456 C CB  . PHE E 5 256 ? 123.803 106.733 94.565  1.00 95.65  ?  256 PHE R CB  1 
ATOM   8457 C CG  . PHE E 5 256 ? 122.676 106.977 93.601  1.00 95.65  ?  256 PHE R CG  1 
ATOM   8458 C CD1 . PHE E 5 256 ? 122.842 107.818 92.513  1.00 95.65  ?  256 PHE R CD1 1 
ATOM   8459 C CD2 . PHE E 5 256 ? 121.443 106.375 93.792  1.00 95.65  ?  256 PHE R CD2 1 
ATOM   8460 C CE1 . PHE E 5 256 ? 121.804 108.046 91.629  1.00 95.65  ?  256 PHE R CE1 1 
ATOM   8461 C CE2 . PHE E 5 256 ? 120.401 106.601 92.913  1.00 95.65  ?  256 PHE R CE2 1 
ATOM   8462 C CZ  . PHE E 5 256 ? 120.582 107.437 91.830  1.00 95.65  ?  256 PHE R CZ  1 
ATOM   8463 N N   . PHE E 5 257 ? 126.687 106.861 93.117  1.00 96.25  ?  257 PHE R N   1 
ATOM   8464 C CA  . PHE E 5 257 ? 127.482 107.383 92.012  1.00 96.25  ?  257 PHE R CA  1 
ATOM   8465 C C   . PHE E 5 257 ? 128.297 106.299 91.319  1.00 96.25  ?  257 PHE R C   1 
ATOM   8466 O O   . PHE E 5 257 ? 128.765 106.519 90.197  1.00 96.25  ?  257 PHE R O   1 
ATOM   8467 C CB  . PHE E 5 257 ? 128.408 108.491 92.522  1.00 96.25  ?  257 PHE R CB  1 
ATOM   8468 C CG  . PHE E 5 257 ? 129.359 109.016 91.484  1.00 96.25  ?  257 PHE R CG  1 
ATOM   8469 C CD1 . PHE E 5 257 ? 128.954 109.983 90.579  1.00 96.25  ?  257 PHE R CD1 1 
ATOM   8470 C CD2 . PHE E 5 257 ? 130.660 108.547 91.417  1.00 96.25  ?  257 PHE R CD2 1 
ATOM   8471 C CE1 . PHE E 5 257 ? 129.827 110.468 89.624  1.00 96.25  ?  257 PHE R CE1 1 
ATOM   8472 C CE2 . PHE E 5 257 ? 131.538 109.029 90.465  1.00 96.25  ?  257 PHE R CE2 1 
ATOM   8473 C CZ  . PHE E 5 257 ? 131.120 109.990 89.568  1.00 96.25  ?  257 PHE R CZ  1 
ATOM   8474 N N   . LEU E 5 258 ? 128.473 105.138 91.950  1.00 96.25  ?  258 LEU R N   1 
ATOM   8475 C CA  . LEU E 5 258 ? 129.296 104.065 91.406  1.00 96.25  ?  258 LEU R CA  1 
ATOM   8476 C C   . LEU E 5 258 ? 128.478 102.849 90.986  1.00 96.25  ?  258 LEU R C   1 
ATOM   8477 O O   . LEU E 5 258 ? 129.055 101.782 90.749  1.00 96.25  ?  258 LEU R O   1 
ATOM   8478 C CB  . LEU E 5 258 ? 130.356 103.650 92.429  1.00 96.25  ?  258 LEU R CB  1 
ATOM   8479 C CG  . LEU E 5 258 ? 131.293 104.761 92.909  1.00 96.25  ?  258 LEU R CG  1 
ATOM   8480 C CD1 . LEU E 5 258 ? 132.229 104.242 93.989  1.00 96.25  ?  258 LEU R CD1 1 
ATOM   8481 C CD2 . LEU E 5 258 ? 132.084 105.343 91.748  1.00 96.25  ?  258 LEU R CD2 1 
ATOM   8482 N N   . CYS E 5 259 ? 127.160 102.978 90.890  1.00 96.81  ?  259 CYS R N   1 
ATOM   8483 C CA  . CYS E 5 259 ? 126.303 101.861 90.505  1.00 96.81  ?  259 CYS R CA  1 
ATOM   8484 C C   . CYS E 5 259 ? 125.367 102.191 89.352  1.00 96.81  ?  259 CYS R C   1 
ATOM   8485 O O   . CYS E 5 259 ? 125.118 101.326 88.509  1.00 96.81  ?  259 CYS R O   1 
ATOM   8486 C CB  . CYS E 5 259 ? 125.483 101.391 91.718  1.00 96.81  ?  259 CYS R CB  1 
ATOM   8487 S SG  . CYS E 5 259 ? 126.467 100.617 93.024  1.00 96.81  ?  259 CYS R SG  1 
ATOM   8488 N N   . PHE E 5 260 ? 124.844 103.415 89.291  1.00 96.92  ?  260 PHE R N   1 
ATOM   8489 C CA  . PHE E 5 260 ? 123.895 103.808 88.256  1.00 96.92  ?  260 PHE R CA  1 
ATOM   8490 C C   . PHE E 5 260 ? 124.534 104.657 87.164  1.00 96.92  ?  260 PHE R C   1 
ATOM   8491 O O   . PHE E 5 260 ? 124.425 104.323 85.981  1.00 96.92  ?  260 PHE R O   1 
ATOM   8492 C CB  . PHE E 5 260 ? 122.720 104.571 88.884  1.00 96.92  ?  260 PHE R CB  1 
ATOM   8493 C CG  . PHE E 5 260 ? 121.792 103.706 89.695  1.00 96.92  ?  260 PHE R CG  1 
ATOM   8494 C CD1 . PHE E 5 260 ? 121.401 102.457 89.240  1.00 96.92  ?  260 PHE R CD1 1 
ATOM   8495 C CD2 . PHE E 5 260 ? 121.311 104.147 90.915  1.00 96.92  ?  260 PHE R CD2 1 
ATOM   8496 C CE1 . PHE E 5 260 ? 120.548 101.667 89.987  1.00 96.92  ?  260 PHE R CE1 1 
ATOM   8497 C CE2 . PHE E 5 260 ? 120.458 103.362 91.666  1.00 96.92  ?  260 PHE R CE2 1 
ATOM   8498 C CZ  . PHE E 5 260 ? 120.077 102.120 91.201  1.00 96.92  ?  260 PHE R CZ  1 
ATOM   8499 N N   . LEU E 5 261 ? 125.198 105.752 87.534  1.00 95.66  ?  261 LEU R N   1 
ATOM   8500 C CA  . LEU E 5 261 ? 125.810 106.613 86.524  1.00 95.66  ?  261 LEU R CA  1 
ATOM   8501 C C   . LEU E 5 261 ? 126.796 105.855 85.648  1.00 95.66  ?  261 LEU R C   1 
ATOM   8502 O O   . LEU E 5 261 ? 126.731 105.999 84.415  1.00 95.66  ?  261 LEU R O   1 
ATOM   8503 C CB  . LEU E 5 261 ? 126.474 107.815 87.203  1.00 95.66  ?  261 LEU R CB  1 
ATOM   8504 C CG  . LEU E 5 261 ? 125.535 108.969 87.564  1.00 95.66  ?  261 LEU R CG  1 
ATOM   8505 C CD1 . LEU E 5 261 ? 124.527 108.544 88.621  1.00 95.66  ?  261 LEU R CD1 1 
ATOM   8506 C CD2 . LEU E 5 261 ? 126.328 110.177 88.032  1.00 95.66  ?  261 LEU R CD2 1 
ATOM   8507 N N   . PRO E 5 262 ? 127.718 105.053 86.188  1.00 97.04  ?  262 PRO R N   1 
ATOM   8508 C CA  . PRO E 5 262 ? 128.567 104.237 85.307  1.00 97.04  ?  262 PRO R CA  1 
ATOM   8509 C C   . PRO E 5 262 ? 127.770 103.301 84.420  1.00 97.04  ?  262 PRO R C   1 
ATOM   8510 O O   . PRO E 5 262 ? 128.074 103.179 83.228  1.00 97.04  ?  262 PRO R O   1 
ATOM   8511 C CB  . PRO E 5 262 ? 129.455 103.463 86.292  1.00 97.04  ?  262 PRO R CB  1 
ATOM   8512 C CG  . PRO E 5 262 ? 129.442 104.269 87.542  1.00 97.04  ?  262 PRO R CG  1 
ATOM   8513 C CD  . PRO E 5 262 ? 128.084 104.899 87.605  1.00 97.04  ?  262 PRO R CD  1 
ATOM   8514 N N   . TYR E 5 263 ? 126.748 102.641 84.970  1.00 97.49  ?  263 TYR R N   1 
ATOM   8515 C CA  . TYR E 5 263 ? 125.918 101.743 84.175  1.00 97.49  ?  263 TYR R CA  1 
ATOM   8516 C C   . TYR E 5 263 ? 125.217 102.485 83.045  1.00 97.49  ?  263 TYR R C   1 
ATOM   8517 O O   . TYR E 5 263 ? 125.213 102.018 81.899  1.00 97.49  ?  263 TYR R O   1 
ATOM   8518 C CB  . TYR E 5 263 ? 124.894 101.050 85.076  1.00 97.49  ?  263 TYR R CB  1 
ATOM   8519 C CG  . TYR E 5 263 ? 123.730 100.428 84.334  1.00 97.49  ?  263 TYR R CG  1 
ATOM   8520 C CD1 . TYR E 5 263 ? 123.847 99.181  83.736  1.00 97.49  ?  263 TYR R CD1 1 
ATOM   8521 C CD2 . TYR E 5 263 ? 122.511 101.087 84.241  1.00 97.49  ?  263 TYR R CD2 1 
ATOM   8522 C CE1 . TYR E 5 263 ? 122.784 98.610  83.060  1.00 97.49  ?  263 TYR R CE1 1 
ATOM   8523 C CE2 . TYR E 5 263 ? 121.443 100.524 83.569  1.00 97.49  ?  263 TYR R CE2 1 
ATOM   8524 C CZ  . TYR E 5 263 ? 121.585 99.286  82.981  1.00 97.49  ?  263 TYR R CZ  1 
ATOM   8525 O OH  . TYR E 5 263 ? 120.523 98.723  82.310  1.00 97.49  ?  263 TYR R OH  1 
ATOM   8526 N N   . HIS E 5 264 ? 124.623 103.642 83.350  1.00 96.94  ?  264 HIS R N   1 
ATOM   8527 C CA  . HIS E 5 264 ? 123.926 104.405 82.322  1.00 96.94  ?  264 HIS R CA  1 
ATOM   8528 C C   . HIS E 5 264 ? 124.890 104.889 81.246  1.00 96.94  ?  264 HIS R C   1 
ATOM   8529 O O   . HIS E 5 264 ? 124.597 104.777 80.050  1.00 96.94  ?  264 HIS R O   1 
ATOM   8530 C CB  . HIS E 5 264 ? 123.187 105.583 82.956  1.00 96.94  ?  264 HIS R CB  1 
ATOM   8531 C CG  . HIS E 5 264 ? 122.032 105.174 83.816  1.00 96.94  ?  264 HIS R CG  1 
ATOM   8532 N ND1 . HIS E 5 264 ? 122.158 104.937 85.168  1.00 96.94  ?  264 HIS R ND1 1 
ATOM   8533 C CD2 . HIS E 5 264 ? 120.731 104.949 83.515  1.00 96.94  ?  264 HIS R CD2 1 
ATOM   8534 C CE1 . HIS E 5 264 ? 120.983 104.591 85.664  1.00 96.94  ?  264 HIS R CE1 1 
ATOM   8535 N NE2 . HIS E 5 264 ? 120.100 104.591 84.681  1.00 96.94  ?  264 HIS R NE2 1 
ATOM   8536 N N   . THR E 5 265 ? 126.046 105.421 81.648  1.00 96.06  ?  265 THR R N   1 
ATOM   8537 C CA  . THR E 5 265 ? 127.022 105.882 80.666  1.00 96.06  ?  265 THR R CA  1 
ATOM   8538 C C   . THR E 5 265 ? 127.498 104.735 79.783  1.00 96.06  ?  265 THR R C   1 
ATOM   8539 O O   . THR E 5 265 ? 127.652 104.900 78.567  1.00 96.06  ?  265 THR R O   1 
ATOM   8540 C CB  . THR E 5 265 ? 128.210 106.539 81.369  1.00 96.06  ?  265 THR R CB  1 
ATOM   8541 O OG1 . THR E 5 265 ? 128.751 105.640 82.344  1.00 96.06  ?  265 THR R OG1 1 
ATOM   8542 C CG2 . THR E 5 265 ? 127.783 107.834 82.049  1.00 96.06  ?  265 THR R CG2 1 
ATOM   8543 N N   . LEU E 5 266 ? 127.732 103.561 80.375  1.00 96.53  ?  266 LEU R N   1 
ATOM   8544 C CA  . LEU E 5 266 ? 128.230 102.430 79.601  1.00 96.53  ?  266 LEU R CA  1 
ATOM   8545 C C   . LEU E 5 266 ? 127.181 101.938 78.612  1.00 96.53  ?  266 LEU R C   1 
ATOM   8546 O O   . LEU E 5 266 ? 127.484 101.696 77.438  1.00 96.53  ?  266 LEU R O   1 
ATOM   8547 C CB  . LEU E 5 266 ? 128.664 101.306 80.543  1.00 96.53  ?  266 LEU R CB  1 
ATOM   8548 C CG  . LEU E 5 266 ? 129.962 101.577 81.312  1.00 96.53  ?  266 LEU R CG  1 
ATOM   8549 C CD1 . LEU E 5 266 ? 130.182 100.536 82.398  1.00 96.53  ?  266 LEU R CD1 1 
ATOM   8550 C CD2 . LEU E 5 266 ? 131.153 101.617 80.364  1.00 96.53  ?  266 LEU R CD2 1 
ATOM   8551 N N   . ARG E 5 267 ? 125.932 101.790 79.063  1.00 95.36  ?  267 ARG R N   1 
ATOM   8552 C CA  . ARG E 5 267 ? 124.887 101.356 78.142  1.00 95.36  ?  267 ARG R CA  1 
ATOM   8553 C C   . ARG E 5 267 ? 124.641 102.392 77.054  1.00 95.36  ?  267 ARG R C   1 
ATOM   8554 O O   . ARG E 5 267 ? 124.320 102.031 75.916  1.00 95.36  ?  267 ARG R O   1 
ATOM   8555 C CB  . ARG E 5 267 ? 123.592 101.059 78.899  1.00 95.36  ?  267 ARG R CB  1 
ATOM   8556 C CG  . ARG E 5 267 ? 123.023 102.239 79.657  1.00 95.36  ?  267 ARG R CG  1 
ATOM   8557 C CD  . ARG E 5 267 ? 121.803 101.837 80.470  1.00 95.36  ?  267 ARG R CD  1 
ATOM   8558 N NE  . ARG E 5 267 ? 120.587 101.799 79.661  1.00 95.36  ?  267 ARG R NE  1 
ATOM   8559 C CZ  . ARG E 5 267 ? 119.769 102.833 79.478  1.00 95.36  ?  267 ARG R CZ  1 
ATOM   8560 N NH1 . ARG E 5 267 ? 118.688 102.694 78.723  1.00 95.36  1  267 ARG R NH1 1 
ATOM   8561 N NH2 . ARG E 5 267 ? 120.027 104.006 80.043  1.00 95.36  ?  267 ARG R NH2 1 
ATOM   8562 N N   . THR E 5 268 ? 124.805 103.679 77.370  1.00 95.27  ?  268 THR R N   1 
ATOM   8563 C CA  . THR E 5 268 ? 124.625 104.714 76.357  1.00 95.27  ?  268 THR R CA  1 
ATOM   8564 C C   . THR E 5 268 ? 125.728 104.647 75.308  1.00 95.27  ?  268 THR R C   1 
ATOM   8565 O O   . THR E 5 268 ? 125.452 104.652 74.103  1.00 95.27  ?  268 THR R O   1 
ATOM   8566 C CB  . THR E 5 268 ? 124.593 106.094 77.017  1.00 95.27  ?  268 THR R CB  1 
ATOM   8567 O OG1 . THR E 5 268 ? 123.546 106.136 77.994  1.00 95.27  ?  268 THR R OG1 1 
ATOM   8568 C CG2 . THR E 5 268 ? 124.358 107.182 75.977  1.00 95.27  ?  268 THR R CG2 1 
ATOM   8569 N N   . VAL E 5 269 ? 126.989 104.585 75.747  1.00 95.06  ?  269 VAL R N   1 
ATOM   8570 C CA  . VAL E 5 269 ? 128.092 104.506 74.797  1.00 95.06  ?  269 VAL R CA  1 
ATOM   8571 C C   . VAL E 5 269 ? 128.069 103.194 74.024  1.00 95.06  ?  269 VAL R C   1 
ATOM   8572 O O   . VAL E 5 269 ? 128.627 103.121 72.922  1.00 95.06  ?  269 VAL R O   1 
ATOM   8573 C CB  . VAL E 5 269 ? 129.445 104.689 75.513  1.00 95.06  ?  269 VAL R CB  1 
ATOM   8574 C CG1 . VAL E 5 269 ? 129.704 103.546 76.478  1.00 95.06  ?  269 VAL R CG1 1 
ATOM   8575 C CG2 . VAL E 5 269 ? 130.573 104.804 74.498  1.00 95.06  ?  269 VAL R CG2 1 
ATOM   8576 N N   . HIS E 5 270 ? 127.437 102.151 74.568  1.00 92.57  ?  270 HIS R N   1 
ATOM   8577 C CA  . HIS E 5 270 ? 127.338 100.890 73.842  1.00 92.57  ?  270 HIS R CA  1 
ATOM   8578 C C   . HIS E 5 270 ? 126.210 100.918 72.818  1.00 92.57  ?  270 HIS R C   1 
ATOM   8579 O O   . HIS E 5 270 ? 126.355 100.374 71.717  1.00 92.57  ?  270 HIS R O   1 
ATOM   8580 C CB  . HIS E 5 270 ? 127.132 99.736  74.825  1.00 92.57  ?  270 HIS R CB  1 
ATOM   8581 C CG  . HIS E 5 270 ? 127.038 98.394  74.168  1.00 92.57  ?  270 HIS R CG  1 
ATOM   8582 N ND1 . HIS E 5 270 ? 128.059 97.863  73.410  1.00 92.57  ?  270 HIS R ND1 1 
ATOM   8583 C CD2 . HIS E 5 270 ? 126.043 97.476  74.156  1.00 92.57  ?  270 HIS R CD2 1 
ATOM   8584 C CE1 . HIS E 5 270 ? 127.698 96.675  72.960  1.00 92.57  ?  270 HIS R CE1 1 
ATOM   8585 N NE2 . HIS E 5 270 ? 126.479 96.416  73.398  1.00 92.57  ?  270 HIS R NE2 1 
ATOM   8586 N N   . LEU E 5 271 ? 125.082 101.546 73.158  1.00 91.83  ?  271 LEU R N   1 
ATOM   8587 C CA  . LEU E 5 271 ? 123.946 101.584 72.243  1.00 91.83  ?  271 LEU R CA  1 
ATOM   8588 C C   . LEU E 5 271 ? 124.054 102.719 71.234  1.00 91.83  ?  271 LEU R C   1 
ATOM   8589 O O   . LEU E 5 271 ? 123.562 102.586 70.108  1.00 91.83  ?  271 LEU R O   1 
ATOM   8590 C CB  . LEU E 5 271 ? 122.641 101.713 73.031  1.00 91.83  ?  271 LEU R CB  1 
ATOM   8591 C CG  . LEU E 5 271 ? 122.237 100.494 73.861  1.00 91.83  ?  271 LEU R CG  1 
ATOM   8592 C CD1 . LEU E 5 271 ? 121.005 100.801 74.697  1.00 91.83  ?  271 LEU R CD1 1 
ATOM   8593 C CD2 . LEU E 5 271 ? 121.989 99.292  72.962  1.00 91.83  ?  271 LEU R CD2 1 
ATOM   8594 N N   . THR E 5 272 ? 124.683 103.836 71.610  1.00 90.25  ?  272 THR R N   1 
ATOM   8595 C CA  . THR E 5 272 ? 124.800 104.959 70.685  1.00 90.25  ?  272 THR R CA  1 
ATOM   8596 C C   . THR E 5 272 ? 125.535 104.561 69.413  1.00 90.25  ?  272 THR R C   1 
ATOM   8597 O O   . THR E 5 272 ? 125.277 105.126 68.344  1.00 90.25  ?  272 THR R O   1 
ATOM   8598 C CB  . THR E 5 272 ? 125.514 106.130 71.363  1.00 90.25  ?  272 THR R CB  1 
ATOM   8599 O OG1 . THR E 5 272 ? 125.505 107.269 70.493  1.00 90.25  ?  272 THR R OG1 1 
ATOM   8600 C CG2 . THR E 5 272 ? 126.954 105.765 71.697  1.00 90.25  ?  272 THR R CG2 1 
ATOM   8601 N N   . THR E 5 273 ? 126.451 103.596 69.504  1.00 90.96  ?  273 THR R N   1 
ATOM   8602 C CA  . THR E 5 273 ? 127.199 103.085 68.354  1.00 90.96  ?  273 THR R CA  1 
ATOM   8603 C C   . THR E 5 273 ? 127.178 101.561 68.437  1.00 90.96  ?  273 THR R C   1 
ATOM   8604 O O   . THR E 5 273 ? 128.059 100.951 69.048  1.00 90.96  ?  273 THR R O   1 
ATOM   8605 C CB  . THR E 5 273 ? 128.626 103.629 68.334  1.00 90.96  ?  273 THR R CB  1 
ATOM   8606 O OG1 . THR E 5 273 ? 129.259 103.372 69.595  1.00 90.96  ?  273 THR R OG1 1 
ATOM   8607 C CG2 . THR E 5 273 ? 128.625 105.127 68.060  1.00 90.96  ?  273 THR R CG2 1 
ATOM   8608 N N   . TRP E 5 274 ? 126.167 100.951 67.820  1.00 87.96  ?  274 TRP R N   1 
ATOM   8609 C CA  . TRP E 5 274 ? 126.006 99.498  67.801  1.00 87.96  ?  274 TRP R CA  1 
ATOM   8610 C C   . TRP E 5 274 ? 125.809 99.069  66.350  1.00 87.96  ?  274 TRP R C   1 
ATOM   8611 O O   . TRP E 5 274 ? 124.713 99.206  65.799  1.00 87.96  ?  274 TRP R O   1 
ATOM   8612 C CB  . TRP E 5 274 ? 124.834 99.060  68.674  1.00 87.96  ?  274 TRP R CB  1 
ATOM   8613 C CG  . TRP E 5 274 ? 124.744 97.574  68.852  1.00 87.96  ?  274 TRP R CG  1 
ATOM   8614 C CD1 . TRP E 5 274 ? 125.301 96.834  69.854  1.00 87.96  ?  274 TRP R CD1 1 
ATOM   8615 C CD2 . TRP E 5 274 ? 124.057 96.646  68.003  1.00 87.96  ?  274 TRP R CD2 1 
ATOM   8616 N NE1 . TRP E 5 274 ? 125.004 95.504  69.683  1.00 87.96  ?  274 TRP R NE1 1 
ATOM   8617 C CE2 . TRP E 5 274 ? 124.241 95.362  68.554  1.00 87.96  ?  274 TRP R CE2 1 
ATOM   8618 C CE3 . TRP E 5 274 ? 123.304 96.776  66.832  1.00 87.96  ?  274 TRP R CE3 1 
ATOM   8619 C CZ2 . TRP E 5 274 ? 123.700 94.216  67.974  1.00 87.96  ?  274 TRP R CZ2 1 
ATOM   8620 C CZ3 . TRP E 5 274 ? 122.768 95.637  66.258  1.00 87.96  ?  274 TRP R CZ3 1 
ATOM   8621 C CH2 . TRP E 5 274 ? 122.968 94.374  66.829  1.00 87.96  ?  274 TRP R CH2 1 
ATOM   8622 N N   . LYS E 5 275 ? 126.871 98.556  65.736  1.00 84.84  ?  275 LYS R N   1 
ATOM   8623 C CA  . LYS E 5 275 ? 126.842 98.091  64.359  1.00 84.84  ?  275 LYS R CA  1 
ATOM   8624 C C   . LYS E 5 275 ? 127.085 96.588  64.314  1.00 84.84  ?  275 LYS R C   1 
ATOM   8625 O O   . LYS E 5 275 ? 127.718 96.018  65.207  1.00 84.84  ?  275 LYS R O   1 
ATOM   8626 C CB  . LYS E 5 275 ? 127.893 98.816  63.511  1.00 84.84  ?  275 LYS R CB  1 
ATOM   8627 C CG  . LYS E 5 275 ? 129.322 98.642  64.008  1.00 84.84  ?  275 LYS R CG  1 
ATOM   8628 C CD  . LYS E 5 275 ? 130.301 99.524  63.242  1.00 84.84  ?  275 LYS R CD  1 
ATOM   8629 C CE  . LYS E 5 275 ? 130.390 99.140  61.771  1.00 84.84  ?  275 LYS R CE  1 
ATOM   8630 N NZ  . LYS E 5 275 ? 130.814 97.726  61.580  1.00 84.84  1  275 LYS R NZ  1 
ATOM   8631 N N   . VAL E 5 276 ? 126.566 95.950  63.263  1.00 80.49  ?  276 VAL R N   1 
ATOM   8632 C CA  . VAL E 5 276 ? 126.729 94.510  63.111  1.00 80.49  ?  276 VAL R CA  1 
ATOM   8633 C C   . VAL E 5 276 ? 128.209 94.164  63.142  1.00 80.49  ?  276 VAL R C   1 
ATOM   8634 O O   . VAL E 5 276 ? 129.020 94.772  62.436  1.00 80.49  ?  276 VAL R O   1 
ATOM   8635 C CB  . VAL E 5 276 ? 126.061 94.028  61.810  1.00 80.49  ?  276 VAL R CB  1 
ATOM   8636 C CG1 . VAL E 5 276 ? 124.566 94.318  61.840  1.00 80.49  ?  276 VAL R CG1 1 
ATOM   8637 C CG2 . VAL E 5 276 ? 126.714 94.674  60.594  1.00 80.49  ?  276 VAL R CG2 1 
ATOM   8638 N N   . GLY E 5 277 ? 128.564 93.183  63.969  1.00 79.54  ?  277 GLY R N   1 
ATOM   8639 C CA  . GLY E 5 277 ? 129.945 92.765  64.103  1.00 79.54  ?  277 GLY R CA  1 
ATOM   8640 C C   . GLY E 5 277 ? 130.320 92.442  65.534  1.00 79.54  ?  277 GLY R C   1 
ATOM   8641 O O   . GLY E 5 277 ? 129.511 91.893  66.288  1.00 79.54  ?  277 GLY R O   1 
ATOM   8642 N N   . LEU E 5 278 ? 131.547 92.779  65.919  1.00 86.31  ?  278 LEU R N   1 
ATOM   8643 C CA  . LEU E 5 278 ? 132.022 92.501  67.263  1.00 86.31  ?  278 LEU R CA  1 
ATOM   8644 C C   . LEU E 5 278 ? 131.594 93.607  68.224  1.00 86.31  ?  278 LEU R C   1 
ATOM   8645 O O   . LEU E 5 278 ? 131.354 94.753  67.833  1.00 86.31  ?  278 LEU R O   1 
ATOM   8646 C CB  . LEU E 5 278 ? 133.545 92.358  67.271  1.00 86.31  ?  278 LEU R CB  1 
ATOM   8647 C CG  . LEU E 5 278 ? 134.119 91.300  66.324  1.00 86.31  ?  278 LEU R CG  1 
ATOM   8648 C CD1 . LEU E 5 278 ? 135.639 91.302  66.378  1.00 86.31  ?  278 LEU R CD1 1 
ATOM   8649 C CD2 . LEU E 5 278 ? 133.571 89.922  66.660  1.00 86.31  ?  278 LEU R CD2 1 
ATOM   8650 N N   . CYS E 5 279 ? 131.504 93.248  69.506  1.00 82.82  ?  279 CYS R N   1 
ATOM   8651 C CA  . CYS E 5 279 ? 131.154 94.188  70.561  1.00 82.82  ?  279 CYS R CA  1 
ATOM   8652 C C   . CYS E 5 279 ? 132.367 94.934  71.101  1.00 82.82  ?  279 CYS R C   1 
ATOM   8653 O O   . CYS E 5 279 ? 132.293 95.510  72.192  1.00 82.82  ?  279 CYS R O   1 
ATOM   8654 C CB  . CYS E 5 279 ? 130.444 93.459  71.704  1.00 82.82  ?  279 CYS R CB  1 
ATOM   8655 S SG  . CYS E 5 279 ? 131.428 92.156  72.477  1.00 82.82  ?  279 CYS R SG  1 
ATOM   8656 N N   . LYS E 5 280 ? 133.482 94.915  70.369  1.00 87.85  ?  280 LYS R N   1 
ATOM   8657 C CA  . LYS E 5 280 ? 134.702 95.624  70.740  1.00 87.85  ?  280 LYS R CA  1 
ATOM   8658 C C   . LYS E 5 280 ? 135.446 94.917  71.869  1.00 87.85  ?  280 LYS R C   1 
ATOM   8659 O O   . LYS E 5 280 ? 136.539 95.347  72.253  1.00 87.85  ?  280 LYS R O   1 
ATOM   8660 C CB  . LYS E 5 280 ? 134.391 97.071  71.138  1.00 87.85  ?  280 LYS R CB  1 
ATOM   8661 C CG  . LYS E 5 280 ? 133.563 97.846  70.111  1.00 87.85  ?  280 LYS R CG  1 
ATOM   8662 C CD  . LYS E 5 280 ? 134.270 97.969  68.766  1.00 87.85  ?  280 LYS R CD  1 
ATOM   8663 C CE  . LYS E 5 280 ? 135.524 98.827  68.851  1.00 87.85  ?  280 LYS R CE  1 
ATOM   8664 N NZ  . LYS E 5 280 ? 135.237 100.198 69.348  1.00 87.85  1  280 LYS R NZ  1 
ATOM   8665 N N   . ASP E 5 281 ? 134.875 93.838  72.407  1.00 87.43  ?  281 ASP R N   1 
ATOM   8666 C CA  . ASP E 5 281 ? 135.474 92.992  73.436  1.00 87.43  ?  281 ASP R CA  1 
ATOM   8667 C C   . ASP E 5 281 ? 135.639 93.696  74.777  1.00 87.43  ?  281 ASP R C   1 
ATOM   8668 O O   . ASP E 5 281 ? 136.034 93.043  75.751  1.00 87.43  ?  281 ASP R O   1 
ATOM   8669 C CB  . ASP E 5 281 ? 136.845 92.448  73.008  1.00 87.43  ?  281 ASP R CB  1 
ATOM   8670 C CG  . ASP E 5 281 ? 136.759 91.518  71.816  1.00 87.43  ?  281 ASP R CG  1 
ATOM   8671 O OD1 . ASP E 5 281 ? 135.681 90.928  71.596  1.00 87.43  ?  281 ASP R OD1 1 
ATOM   8672 O OD2 . ASP E 5 281 ? 137.772 91.375  71.098  1.00 87.43  ?  281 ASP R OD2 1 
ATOM   8673 N N   . ARG E 5 282 ? 135.347 94.993  74.870  1.00 93.07  ?  282 ARG R N   1 
ATOM   8674 C CA  . ARG E 5 282 ? 135.600 95.770  76.077  1.00 93.07  ?  282 ARG R CA  1 
ATOM   8675 C C   . ARG E 5 282 ? 134.349 96.450  76.606  1.00 93.07  ?  282 ARG R C   1 
ATOM   8676 O O   . ARG E 5 282 ? 134.084 96.396  77.813  1.00 93.07  ?  282 ARG R O   1 
ATOM   8677 C CB  . ARG E 5 282 ? 136.695 96.815  75.800  1.00 93.07  ?  282 ARG R CB  1 
ATOM   8678 C CG  . ARG E 5 282 ? 137.139 97.612  77.021  1.00 93.07  ?  282 ARG R CG  1 
ATOM   8679 C CD  . ARG E 5 282 ? 136.397 98.936  77.126  1.00 93.07  ?  282 ARG R CD  1 
ATOM   8680 N NE  . ARG E 5 282 ? 136.849 99.743  78.257  1.00 93.07  ?  282 ARG R NE  1 
ATOM   8681 C CZ  . ARG E 5 282 ? 136.315 100.912 78.600  1.00 93.07  ?  282 ARG R CZ  1 
ATOM   8682 N NH1 . ARG E 5 282 ? 135.305 101.414 77.903  1.00 93.07  1  282 ARG R NH1 1 
ATOM   8683 N NH2 . ARG E 5 282 ? 136.790 101.580 79.642  1.00 93.07  ?  282 ARG R NH2 1 
ATOM   8684 N N   . LEU E 5 283 ? 133.570 97.099  75.738  1.00 94.77  ?  283 LEU R N   1 
ATOM   8685 C CA  . LEU E 5 283 ? 132.368 97.782  76.205  1.00 94.77  ?  283 LEU R CA  1 
ATOM   8686 C C   . LEU E 5 283 ? 131.379 96.795  76.809  1.00 94.77  ?  283 LEU R C   1 
ATOM   8687 O O   . LEU E 5 283 ? 130.690 97.112  77.784  1.00 94.77  ?  283 LEU R O   1 
ATOM   8688 C CB  . LEU E 5 283 ? 131.717 98.558  75.059  1.00 94.77  ?  283 LEU R CB  1 
ATOM   8689 C CG  . LEU E 5 283 ? 132.385 99.872  74.644  1.00 94.77  ?  283 LEU R CG  1 
ATOM   8690 C CD1 . LEU E 5 283 ? 133.802 99.641  74.136  1.00 94.77  ?  283 LEU R CD1 1 
ATOM   8691 C CD2 . LEU E 5 283 ? 131.547 100.587 73.593  1.00 94.77  ?  283 LEU R CD2 1 
ATOM   8692 N N   . HIS E 5 284 ? 131.300 95.587  76.246  1.00 93.07  ?  284 HIS R N   1 
ATOM   8693 C CA  . HIS E 5 284 ? 130.353 94.599  76.752  1.00 93.07  ?  284 HIS R CA  1 
ATOM   8694 C C   . HIS E 5 284 ? 130.745 94.121  78.146  1.00 93.07  ?  284 HIS R C   1 
ATOM   8695 O O   . HIS E 5 284 ? 129.879 93.912  79.003  1.00 93.07  ?  284 HIS R O   1 
ATOM   8696 C CB  . HIS E 5 284 ? 130.265 93.421  75.783  1.00 93.07  ?  284 HIS R CB  1 
ATOM   8697 C CG  . HIS E 5 284 ? 128.983 92.655  75.879  1.00 93.07  ?  284 HIS R CG  1 
ATOM   8698 N ND1 . HIS E 5 284 ? 127.790 93.138  75.384  1.00 93.07  ?  284 HIS R ND1 1 
ATOM   8699 C CD2 . HIS E 5 284 ? 128.706 91.442  76.410  1.00 93.07  ?  284 HIS R CD2 1 
ATOM   8700 C CE1 . HIS E 5 284 ? 126.834 92.254  75.607  1.00 93.07  ?  284 HIS R CE1 1 
ATOM   8701 N NE2 . HIS E 5 284 ? 127.363 91.216  76.228  1.00 93.07  ?  284 HIS R NE2 1 
ATOM   8702 N N   . LYS E 5 285 ? 132.045 93.938  78.389  1.00 95.37  ?  285 LYS R N   1 
ATOM   8703 C CA  . LYS E 5 285 ? 132.508 93.538  79.715  1.00 95.37  ?  285 LYS R CA  1 
ATOM   8704 C C   . LYS E 5 285 ? 132.153 94.596  80.755  1.00 95.37  ?  285 LYS R C   1 
ATOM   8705 O O   . LYS E 5 285 ? 131.600 94.284  81.820  1.00 95.37  ?  285 LYS R O   1 
ATOM   8706 C CB  . LYS E 5 285 ? 134.018 93.298  79.683  1.00 95.37  ?  285 LYS R CB  1 
ATOM   8707 C CG  . LYS E 5 285 ? 134.593 92.692  80.954  1.00 95.37  ?  285 LYS R CG  1 
ATOM   8708 C CD  . LYS E 5 285 ? 134.198 91.232  81.103  1.00 95.37  ?  285 LYS R CD  1 
ATOM   8709 C CE  . LYS E 5 285 ? 134.870 90.590  82.307  1.00 95.37  ?  285 LYS R CE  1 
ATOM   8710 N NZ  . LYS E 5 285 ? 136.355 90.655  82.230  1.00 95.37  1  285 LYS R NZ  1 
ATOM   8711 N N   . ALA E 5 286 ? 132.489 95.856  80.468  1.00 97.09  ?  286 ALA R N   1 
ATOM   8712 C CA  . ALA E 5 286 ? 132.126 96.942  81.369  1.00 97.09  ?  286 ALA R CA  1 
ATOM   8713 C C   . ALA E 5 286 ? 130.621 96.985  81.591  1.00 97.09  ?  286 ALA R C   1 
ATOM   8714 O O   . ALA E 5 286 ? 130.157 97.180  82.721  1.00 97.09  ?  286 ALA R O   1 
ATOM   8715 C CB  . ALA E 5 286 ? 132.624 98.275  80.810  1.00 97.09  ?  286 ALA R CB  1 
ATOM   8716 N N   . LEU E 5 287 ? 129.843 96.791  80.524  1.00 96.14  ?  287 LEU R N   1 
ATOM   8717 C CA  . LEU E 5 287 ? 128.392 96.850  80.644  1.00 96.14  ?  287 LEU R CA  1 
ATOM   8718 C C   . LEU E 5 287 ? 127.869 95.753  81.561  1.00 96.14  ?  287 LEU R C   1 
ATOM   8719 O O   . LEU E 5 287 ? 127.019 96.007  82.421  1.00 96.14  ?  287 LEU R O   1 
ATOM   8720 C CB  . LEU E 5 287 ? 127.749 96.744  79.261  1.00 96.14  ?  287 LEU R CB  1 
ATOM   8721 C CG  . LEU E 5 287 ? 126.221 96.817  79.219  1.00 96.14  ?  287 LEU R CG  1 
ATOM   8722 C CD1 . LEU E 5 287 ? 125.720 98.123  79.820  1.00 96.14  ?  287 LEU R CD1 1 
ATOM   8723 C CD2 . LEU E 5 287 ? 125.724 96.659  77.792  1.00 96.14  ?  287 LEU R CD2 1 
ATOM   8724 N N   . VAL E 5 288 ? 128.366 94.525  81.401  1.00 96.13  ?  288 VAL R N   1 
ATOM   8725 C CA  . VAL E 5 288 ? 127.867 93.431  82.228  1.00 96.13  ?  288 VAL R CA  1 
ATOM   8726 C C   . VAL E 5 288 ? 128.276 93.629  83.684  1.00 96.13  ?  288 VAL R C   1 
ATOM   8727 O O   . VAL E 5 288 ? 127.474 93.408  84.601  1.00 96.13  ?  288 VAL R O   1 
ATOM   8728 C CB  . VAL E 5 288 ? 128.339 92.069  81.682  1.00 96.13  ?  288 VAL R CB  1 
ATOM   8729 C CG1 . VAL E 5 288 ? 129.854 91.990  81.619  1.00 96.13  ?  288 VAL R CG1 1 
ATOM   8730 C CG2 . VAL E 5 288 ? 127.787 90.942  82.539  1.00 96.13  ?  288 VAL R CG2 1 
ATOM   8731 N N   . ILE E 5 289 ? 129.516 94.063  83.929  1.00 97.69  ?  289 ILE R N   1 
ATOM   8732 C CA  . ILE E 5 289 ? 129.950 94.223  85.315  1.00 97.69  ?  289 ILE R CA  1 
ATOM   8733 C C   . ILE E 5 289 ? 129.186 95.358  85.987  1.00 97.69  ?  289 ILE R C   1 
ATOM   8734 O O   . ILE E 5 289 ? 128.789 95.249  87.155  1.00 97.69  ?  289 ILE R O   1 
ATOM   8735 C CB  . ILE E 5 289 ? 131.475 94.432  85.398  1.00 97.69  ?  289 ILE R CB  1 
ATOM   8736 C CG1 . ILE E 5 289 ? 131.893 95.709  84.668  1.00 97.69  ?  289 ILE R CG1 1 
ATOM   8737 C CG2 . ILE E 5 289 ? 132.204 93.218  84.838  1.00 97.69  ?  289 ILE R CG2 1 
ATOM   8738 C CD1 . ILE E 5 289 ? 133.387 95.968  84.691  1.00 97.69  ?  289 ILE R CD1 1 
ATOM   8739 N N   . THR E 5 290 ? 128.942 96.457  85.266  1.00 97.95  ?  290 THR R N   1 
ATOM   8740 C CA  . THR E 5 290 ? 128.194 97.556  85.864  1.00 97.95  ?  290 THR R CA  1 
ATOM   8741 C C   . THR E 5 290 ? 126.724 97.198  86.040  1.00 97.95  ?  290 THR R C   1 
ATOM   8742 O O   . THR E 5 290 ? 126.091 97.649  86.999  1.00 97.95  ?  290 THR R O   1 
ATOM   8743 C CB  . THR E 5 290 ? 128.340 98.825  85.021  1.00 97.95  ?  290 THR R CB  1 
ATOM   8744 O OG1 . THR E 5 290 ? 127.762 99.935  85.718  1.00 97.95  ?  290 THR R OG1 1 
ATOM   8745 C CG2 . THR E 5 290 ? 127.654 98.665  83.675  1.00 97.95  ?  290 THR R CG2 1 
ATOM   8746 N N   . LEU E 5 291 ? 126.167 96.377  85.145  1.00 97.29  ?  291 LEU R N   1 
ATOM   8747 C CA  . LEU E 5 291 ? 124.802 95.903  85.337  1.00 97.29  ?  291 LEU R CA  1 
ATOM   8748 C C   . LEU E 5 291 ? 124.700 95.024  86.576  1.00 97.29  ?  291 LEU R C   1 
ATOM   8749 O O   . LEU E 5 291 ? 123.718 95.103  87.322  1.00 97.29  ?  291 LEU R O   1 
ATOM   8750 C CB  . LEU E 5 291 ? 124.334 95.144  84.096  1.00 97.29  ?  291 LEU R CB  1 
ATOM   8751 C CG  . LEU E 5 291 ? 122.972 94.450  84.182  1.00 97.29  ?  291 LEU R CG  1 
ATOM   8752 C CD1 . LEU E 5 291 ? 121.867 95.440  84.516  1.00 97.29  ?  291 LEU R CD1 1 
ATOM   8753 C CD2 . LEU E 5 291 ? 122.670 93.732  82.878  1.00 97.29  ?  291 LEU R CD2 1 
ATOM   8754 N N   . ALA E 5 292 ? 125.708 94.182  86.815  1.00 97.46  ?  292 ALA R N   1 
ATOM   8755 C CA  . ALA E 5 292 ? 125.716 93.383  88.036  1.00 97.46  ?  292 ALA R CA  1 
ATOM   8756 C C   . ALA E 5 292 ? 125.838 94.270  89.270  1.00 97.46  ?  292 ALA R C   1 
ATOM   8757 O O   . ALA E 5 292 ? 125.140 94.058  90.270  1.00 97.46  ?  292 ALA R O   1 
ATOM   8758 C CB  . ALA E 5 292 ? 126.857 92.368  87.990  1.00 97.46  ?  292 ALA R CB  1 
ATOM   8759 N N   . LEU E 5 293 ? 126.720 95.271  89.218  1.00 97.64  ?  293 LEU R N   1 
ATOM   8760 C CA  . LEU E 5 293 ? 126.856 96.190  90.344  1.00 97.64  ?  293 LEU R CA  1 
ATOM   8761 C C   . LEU E 5 293 ? 125.551 96.935  90.609  1.00 97.64  ?  293 LEU R C   1 
ATOM   8762 O O   . LEU E 5 293 ? 125.205 97.200  91.766  1.00 97.64  ?  293 LEU R O   1 
ATOM   8763 C CB  . LEU E 5 293 ? 127.993 97.178  90.081  1.00 97.64  ?  293 LEU R CB  1 
ATOM   8764 C CG  . LEU E 5 293 ? 129.406 96.590  90.044  1.00 97.64  ?  293 LEU R CG  1 
ATOM   8765 C CD1 . LEU E 5 293 ? 130.417 97.655  89.646  1.00 97.64  ?  293 LEU R CD1 1 
ATOM   8766 C CD2 . LEU E 5 293 ? 129.779 95.975  91.385  1.00 97.64  ?  293 LEU R CD2 1 
ATOM   8767 N N   . ALA E 5 294 ? 124.816 97.281  89.550  1.00 97.75  ?  294 ALA R N   1 
ATOM   8768 C CA  . ALA E 5 294 ? 123.539 97.965  89.727  1.00 97.75  ?  294 ALA R CA  1 
ATOM   8769 C C   . ALA E 5 294 ? 122.489 97.028  90.307  1.00 97.75  ?  294 ALA R C   1 
ATOM   8770 O O   . ALA E 5 294 ? 121.734 97.414  91.207  1.00 97.75  ?  294 ALA R O   1 
ATOM   8771 C CB  . ALA E 5 294 ? 123.065 98.543  88.395  1.00 97.75  ?  294 ALA R CB  1 
ATOM   8772 N N   . ALA E 5 295 ? 122.419 95.794  89.802  1.00 97.36  ?  295 ALA R N   1 
ATOM   8773 C CA  . ALA E 5 295 ? 121.505 94.814  90.376  1.00 97.36  ?  295 ALA R CA  1 
ATOM   8774 C C   . ALA E 5 295 ? 121.807 94.578  91.848  1.00 97.36  ?  295 ALA R C   1 
ATOM   8775 O O   . ALA E 5 295 ? 120.896 94.289  92.632  1.00 97.36  ?  295 ALA R O   1 
ATOM   8776 C CB  . ALA E 5 295 ? 121.585 93.500  89.598  1.00 97.36  ?  295 ALA R CB  1 
ATOM   8777 N N   . ALA E 5 296 ? 123.077 94.695  92.241  1.00 97.10  ?  296 ALA R N   1 
ATOM   8778 C CA  . ALA E 5 296 ? 123.430 94.631  93.654  1.00 97.10  ?  296 ALA R CA  1 
ATOM   8779 C C   . ALA E 5 296 ? 122.848 95.789  94.453  1.00 97.10  ?  296 ALA R C   1 
ATOM   8780 O O   . ALA E 5 296 ? 122.865 95.743  95.689  1.00 97.10  ?  296 ALA R O   1 
ATOM   8781 C CB  . ALA E 5 296 ? 124.951 94.606  93.813  1.00 97.10  ?  296 ALA R CB  1 
ATOM   8782 N N   . ASN E 5 297 ? 122.340 96.828  93.785  1.00 96.70  ?  297 ASN R N   1 
ATOM   8783 C CA  . ASN E 5 297 ? 121.684 97.911  94.506  1.00 96.70  ?  297 ASN R CA  1 
ATOM   8784 C C   . ASN E 5 297 ? 120.408 97.428  95.184  1.00 96.70  ?  297 ASN R C   1 
ATOM   8785 O O   . ASN E 5 297 ? 120.023 97.959  96.231  1.00 96.70  ?  297 ASN R O   1 
ATOM   8786 C CB  . ASN E 5 297 ? 121.381 99.067  93.553  1.00 96.70  ?  297 ASN R CB  1 
ATOM   8787 C CG  . ASN E 5 297 ? 121.001 100.342 94.281  1.00 96.70  ?  297 ASN R CG  1 
ATOM   8788 O OD1 . ASN E 5 297 ? 120.198 100.323 95.213  1.00 96.70  ?  297 ASN R OD1 1 
ATOM   8789 N ND2 . ASN E 5 297 ? 121.586 101.458 93.862  1.00 96.70  ?  297 ASN R ND2 1 
ATOM   8790 N N   . ALA E 5 298 ? 119.745 96.421  94.610  1.00 96.27  ?  298 ALA R N   1 
ATOM   8791 C CA  . ALA E 5 298 ? 118.564 95.851  95.247  1.00 96.27  ?  298 ALA R CA  1 
ATOM   8792 C C   . ALA E 5 298 ? 118.869 95.320  96.641  1.00 96.27  ?  298 ALA R C   1 
ATOM   8793 O O   . ALA E 5 298 ? 117.973 95.293  97.492  1.00 96.27  ?  298 ALA R O   1 
ATOM   8794 C CB  . ALA E 5 298 ? 117.987 94.732  94.379  1.00 96.27  ?  298 ALA R CB  1 
ATOM   8795 N N   . CYS E 5 299 ? 120.108 94.898  96.892  1.00 95.11  ?  299 CYS R N   1 
ATOM   8796 C CA  . CYS E 5 299 ? 120.531 94.456  98.215  1.00 95.11  ?  299 CYS R CA  1 
ATOM   8797 C C   . CYS E 5 299 ? 121.219 95.552  99.011  1.00 95.11  ?  299 CYS R C   1 
ATOM   8798 O O   . CYS E 5 299 ? 121.152 95.542  100.245 1.00 95.11  ?  299 CYS R O   1 
ATOM   8799 C CB  . CYS E 5 299 ? 121.480 93.260  98.094  1.00 95.11  ?  299 CYS R CB  1 
ATOM   8800 S SG  . CYS E 5 299 ? 120.777 91.849  97.219  1.00 95.11  ?  299 CYS R SG  1 
ATOM   8801 N N   . PHE E 5 300 ? 121.814 96.564  98.374  1.00 94.15  ?  300 PHE R N   1 
ATOM   8802 C CA  . PHE E 5 300 ? 122.377 97.691  99.138  1.00 94.15  ?  300 PHE R CA  1 
ATOM   8803 C C   . PHE E 5 300 ? 121.273 98.594  99.661  1.00 94.15  ?  300 PHE R C   1 
ATOM   8804 O O   . PHE E 5 300 ? 121.257 98.942  100.853 1.00 94.15  ?  300 PHE R O   1 
ATOM   8805 C CB  . PHE E 5 300 ? 123.315 98.564  98.286  1.00 94.15  ?  300 PHE R CB  1 
ATOM   8806 C CG  . PHE E 5 300 ? 124.422 97.815  97.582  1.00 94.15  ?  300 PHE R CG  1 
ATOM   8807 C CD1 . PHE E 5 300 ? 125.033 96.702  98.147  1.00 94.15  ?  300 PHE R CD1 1 
ATOM   8808 C CD2 . PHE E 5 300 ? 124.877 98.262  96.350  1.00 94.15  ?  300 PHE R CD2 1 
ATOM   8809 C CE1 . PHE E 5 300 ? 126.048 96.043  97.483  1.00 94.15  ?  300 PHE R CE1 1 
ATOM   8810 C CE2 . PHE E 5 300 ? 125.892 97.605  95.686  1.00 94.15  ?  300 PHE R CE2 1 
ATOM   8811 C CZ  . PHE E 5 300 ? 126.481 96.498  96.255  1.00 94.15  ?  300 PHE R CZ  1 
ATOM   8812 N N   . ASN E 5 301 ? 120.296 98.906  98.816  1.00 94.46  ?  301 ASN R N   1 
ATOM   8813 C CA  . ASN E 5 301 ? 119.270 99.880  99.200  1.00 94.46  ?  301 ASN R CA  1 
ATOM   8814 C C   . ASN E 5 301 ? 118.480 99.612  100.418 1.00 94.46  ?  301 ASN R C   1 
ATOM   8815 O O   . ASN E 5 301 ? 118.361 100.508 101.245 1.00 94.46  ?  301 ASN R O   1 
ATOM   8816 C CB  . ASN E 5 301 ? 118.149 99.934  98.155  1.00 94.46  ?  301 ASN R CB  1 
ATOM   8817 C CG  . ASN E 5 301 ? 118.325 101.013 97.142  1.00 94.46  ?  301 ASN R CG  1 
ATOM   8818 O OD1 . ASN E 5 301 ? 119.103 101.954 97.311  1.00 94.46  ?  301 ASN R OD1 1 
ATOM   8819 N ND2 . ASN E 5 301 ? 117.581 100.878 96.055  1.00 94.46  ?  301 ASN R ND2 1 
ATOM   8820 N N   . PRO E 5 302 ? 117.977 98.374  100.571 1.00 94.74  ?  302 PRO R N   1 
ATOM   8821 C CA  . PRO E 5 302 ? 117.125 98.249  101.737 1.00 94.74  ?  302 PRO R CA  1 
ATOM   8822 C C   . PRO E 5 302 ? 117.939 98.563  102.935 1.00 94.74  ?  302 PRO R C   1 
ATOM   8823 O O   . PRO E 5 302 ? 117.541 99.463  103.647 1.00 94.74  ?  302 PRO R O   1 
ATOM   8824 C CB  . PRO E 5 302 ? 116.707 96.771  101.736 1.00 94.74  ?  302 PRO R CB  1 
ATOM   8825 C CG  . PRO E 5 302 ? 117.604 96.095  100.760 1.00 94.74  ?  302 PRO R CG  1 
ATOM   8826 C CD  . PRO E 5 302 ? 117.946 97.148  99.761  1.00 94.74  ?  302 PRO R CD  1 
ATOM   8827 N N   . LEU E 5 303 ? 119.135 98.005  103.044 1.00 93.54  ?  303 LEU R N   1 
ATOM   8828 C CA  . LEU E 5 303 ? 119.892 98.201  104.259 1.00 93.54  ?  303 LEU R CA  1 
ATOM   8829 C C   . LEU E 5 303 ? 120.227 99.656  104.439 1.00 93.54  ?  303 LEU R C   1 
ATOM   8830 O O   . LEU E 5 303 ? 119.868 100.243 105.463 1.00 93.54  ?  303 LEU R O   1 
ATOM   8831 C CB  . LEU E 5 303 ? 121.178 97.367  104.236 1.00 93.54  ?  303 LEU R CB  1 
ATOM   8832 C CG  . LEU E 5 303 ? 121.049 95.838  104.132 1.00 93.54  ?  303 LEU R CG  1 
ATOM   8833 C CD1 . LEU E 5 303 ? 122.415 95.202  103.925 1.00 93.54  ?  303 LEU R CD1 1 
ATOM   8834 C CD2 . LEU E 5 303 ? 120.349 95.242  105.348 1.00 93.54  ?  303 LEU R CD2 1 
ATOM   8835 N N   . LEU E 5 304 ? 120.865 100.286 103.436 1.00 94.41  ?  304 LEU R N   1 
ATOM   8836 C CA  . LEU E 5 304 ? 121.276 101.693 103.535 1.00 94.41  ?  304 LEU R CA  1 
ATOM   8837 C C   . LEU E 5 304 ? 120.163 102.569 104.049 1.00 94.41  ?  304 LEU R C   1 
ATOM   8838 O O   . LEU E 5 304 ? 120.398 103.399 104.929 1.00 94.41  ?  304 LEU R O   1 
ATOM   8839 C CB  . LEU E 5 304 ? 121.701 102.264 102.166 1.00 94.41  ?  304 LEU R CB  1 
ATOM   8840 C CG  . LEU E 5 304 ? 123.077 101.936 101.557 1.00 94.41  ?  304 LEU R CG  1 
ATOM   8841 C CD1 . LEU E 5 304 ? 123.021 102.063 100.038 1.00 94.41  ?  304 LEU R CD1 1 
ATOM   8842 C CD2 . LEU E 5 304 ? 124.207 102.804 102.117 1.00 94.41  ?  304 LEU R CD2 1 
ATOM   8843 N N   . TYR E 5 305 ? 118.953 102.373 103.530 1.00 95.43  ?  305 TYR R N   1 
ATOM   8844 C CA  . TYR E 5 305 ? 117.831 103.247 103.888 1.00 95.43  ?  305 TYR R CA  1 
ATOM   8845 C C   . TYR E 5 305 ? 117.088 102.886 105.190 1.00 95.43  ?  305 TYR R C   1 
ATOM   8846 O O   . TYR E 5 305 ? 116.648 103.831 105.853 1.00 95.43  ?  305 TYR R O   1 
ATOM   8847 C CB  . TYR E 5 305 ? 116.876 103.447 102.699 1.00 95.43  ?  305 TYR R CB  1 
ATOM   8848 C CG  . TYR E 5 305 ? 117.420 104.510 101.756 1.00 95.43  ?  305 TYR R CG  1 
ATOM   8849 C CD1 . TYR E 5 305 ? 116.843 105.775 101.681 1.00 95.43  ?  305 TYR R CD1 1 
ATOM   8850 C CD2 . TYR E 5 305 ? 118.552 104.266 100.983 1.00 95.43  ?  305 TYR R CD2 1 
ATOM   8851 C CE1 . TYR E 5 305 ? 117.355 106.747 100.844 1.00 95.43  ?  305 TYR R CE1 1 
ATOM   8852 C CE2 . TYR E 5 305 ? 119.076 105.234 100.158 1.00 95.43  ?  305 TYR R CE2 1 
ATOM   8853 C CZ  . TYR E 5 305 ? 118.476 106.472 100.092 1.00 95.43  ?  305 TYR R CZ  1 
ATOM   8854 O OH  . TYR E 5 305 ? 118.993 107.415 99.240  1.00 95.43  ?  305 TYR R OH  1 
ATOM   8855 N N   . TYR E 5 306 ? 116.951 101.593 105.563 1.00 94.92  ?  306 TYR R N   1 
ATOM   8856 C CA  . TYR E 5 306 ? 116.175 101.248 106.784 1.00 94.92  ?  306 TYR R CA  1 
ATOM   8857 C C   . TYR E 5 306 ? 116.892 100.496 107.884 1.00 94.92  ?  306 TYR R C   1 
ATOM   8858 O O   . TYR E 5 306 ? 116.730 100.847 109.092 1.00 94.92  ?  306 TYR R O   1 
ATOM   8859 C CB  . TYR E 5 306 ? 114.922 100.430 106.449 1.00 94.92  ?  306 TYR R CB  1 
ATOM   8860 C CG  . TYR E 5 306 ? 114.533 100.310 104.993 1.00 94.92  ?  306 TYR R CG  1 
ATOM   8861 C CD1 . TYR E 5 306 ? 114.173 101.424 104.248 1.00 94.92  ?  306 TYR R CD1 1 
ATOM   8862 C CD2 . TYR E 5 306 ? 114.449 99.067  104.385 1.00 94.92  ?  306 TYR R CD2 1 
ATOM   8863 C CE1 . TYR E 5 306 ? 113.790 101.308 102.929 1.00 94.92  ?  306 TYR R CE1 1 
ATOM   8864 C CE2 . TYR E 5 306 ? 114.056 98.942  103.072 1.00 94.92  ?  306 TYR R CE2 1 
ATOM   8865 C CZ  . TYR E 5 306 ? 113.732 100.063 102.348 1.00 94.92  ?  306 TYR R CZ  1 
ATOM   8866 O OH  . TYR E 5 306 ? 113.353 99.931  101.037 1.00 94.92  ?  306 TYR R OH  1 
ATOM   8867 N N   . PHE E 5 307 ? 117.647 99.455  107.518 1.00 93.44  ?  307 PHE R N   1 
ATOM   8868 C CA  . PHE E 5 307 ? 118.245 98.654  108.590 1.00 93.44  ?  307 PHE R CA  1 
ATOM   8869 C C   . PHE E 5 307 ? 119.254 99.381  109.470 1.00 93.44  ?  307 PHE R C   1 
ATOM   8870 O O   . PHE E 5 307 ? 119.505 98.910  110.567 1.00 93.44  ?  307 PHE R O   1 
ATOM   8871 C CB  . PHE E 5 307 ? 118.773 97.307  108.067 1.00 93.44  ?  307 PHE R CB  1 
ATOM   8872 C CG  . PHE E 5 307 ? 117.683 96.287  107.831 1.00 93.44  ?  307 PHE R CG  1 
ATOM   8873 C CD1 . PHE E 5 307 ? 117.371 95.344  108.800 1.00 93.44  ?  307 PHE R CD1 1 
ATOM   8874 C CD2 . PHE E 5 307 ? 116.956 96.283  106.651 1.00 93.44  ?  307 PHE R CD2 1 
ATOM   8875 C CE1 . PHE E 5 307 ? 116.368 94.413  108.588 1.00 93.44  ?  307 PHE R CE1 1 
ATOM   8876 C CE2 . PHE E 5 307 ? 115.956 95.359  106.435 1.00 93.44  ?  307 PHE R CE2 1 
ATOM   8877 C CZ  . PHE E 5 307 ? 115.659 94.421  107.403 1.00 93.44  ?  307 PHE R CZ  1 
ATOM   8878 N N   . ALA E 5 308 ? 119.800 100.508 108.998 1.00 91.20  ?  308 ALA R N   1 
ATOM   8879 C CA  . ALA E 5 308 ? 120.748 101.306 109.781 1.00 91.20  ?  308 ALA R CA  1 
ATOM   8880 C C   . ALA E 5 308 ? 120.064 102.348 110.662 1.00 91.20  ?  308 ALA R C   1 
ATOM   8881 O O   . ALA E 5 308 ? 120.542 102.635 111.759 1.00 91.20  ?  308 ALA R O   1 
ATOM   8882 C CB  . ALA E 5 308 ? 121.728 102.001 108.847 1.00 91.20  ?  308 ALA R CB  1 
ATOM   8883 N N   . GLY E 5 309 ? 118.969 102.933 110.186 1.00 89.65  ?  309 GLY R N   1 
ATOM   8884 C CA  . GLY E 5 309 ? 118.285 103.974 110.939 1.00 89.65  ?  309 GLY R CA  1 
ATOM   8885 C C   . GLY E 5 309 ? 117.653 103.488 112.228 1.00 89.65  ?  309 GLY R C   1 
ATOM   8886 O O   . GLY E 5 309 ? 117.039 102.430 112.236 1.00 89.65  ?  309 GLY R O   1 
ATOM   8887 N N   . GLU E 5 310 ? 117.743 104.273 113.299 1.00 89.59  ?  310 GLU R N   1 
ATOM   8888 C CA  . GLU E 5 310 ? 117.238 103.843 114.613 1.00 89.59  ?  310 GLU R CA  1 
ATOM   8889 C C   . GLU E 5 310 ? 115.736 103.584 114.715 1.00 89.59  ?  310 GLU R C   1 
ATOM   8890 O O   . GLU E 5 310 ? 115.329 102.593 115.317 1.00 89.59  ?  310 GLU R O   1 
ATOM   8891 C CB  . GLU E 5 310 ? 117.621 104.900 115.664 1.00 89.59  ?  310 GLU R CB  1 
ATOM   8892 C CG  . GLU E 5 310 ? 117.142 104.617 117.085 1.00 89.59  ?  310 GLU R CG  1 
ATOM   8893 C CD  . GLU E 5 310 ? 117.607 105.656 118.091 1.00 89.59  ?  310 GLU R CD  1 
ATOM   8894 O OE1 . GLU E 5 310 ? 118.214 106.671 117.689 1.00 89.59  ?  310 GLU R OE1 1 
ATOM   8895 O OE2 . GLU E 5 310 ? 117.354 105.460 119.298 1.00 89.59  ?  310 GLU R OE2 1 
ATOM   8896 N N   . ASN E 5 311 ? 114.910 104.450 114.138 1.00 30.00  ?  311 ASN R N   1 
ATOM   8897 C CA  . ASN E 5 311 ? 113.454 104.309 114.283 1.00 30.00  ?  311 ASN R CA  1 
ATOM   8898 C C   . ASN E 5 311 ? 112.945 102.969 113.757 1.00 30.00  ?  311 ASN R C   1 
ATOM   8899 O O   . ASN E 5 311 ? 112.039 102.384 114.353 1.00 30.00  ?  311 ASN R O   1 
ATOM   8900 C CB  . ASN E 5 311 ? 112.736 105.469 113.578 1.00 30.00  ?  311 ASN R CB  1 
ATOM   8901 C CG  . ASN E 5 311 ? 111.225 105.344 113.629 1.00 30.00  ?  311 ASN R CG  1 
ATOM   8902 O OD1 . ASN E 5 311 ? 110.604 105.668 114.642 1.00 30.00  ?  311 ASN R OD1 1 
ATOM   8903 N ND2 . ASN E 5 311 ? 110.622 104.879 112.537 1.00 30.00  ?  311 ASN R ND2 1 
ATOM   8904 N N   . PHE E 5 312 ? 113.532 102.466 112.674 1.00 91.89  ?  312 PHE R N   1 
ATOM   8905 C CA  . PHE E 5 312 ? 113.087 101.224 112.053 1.00 91.89  ?  312 PHE R CA  1 
ATOM   8906 C C   . PHE E 5 312 ? 113.782 100.084 112.735 1.00 91.89  ?  312 PHE R C   1 
ATOM   8907 O O   . PHE E 5 312 ? 113.241 98.998  112.766 1.00 91.89  ?  312 PHE R O   1 
ATOM   8908 C CB  . PHE E 5 312 ? 113.448 101.190 110.558 1.00 91.89  ?  312 PHE R CB  1 
ATOM   8909 C CG  . PHE E 5 312 ? 113.301 99.826  109.914 1.00 91.89  ?  312 PHE R CG  1 
ATOM   8910 C CD1 . PHE E 5 312 ? 112.102 99.437  109.343 1.00 91.89  ?  312 PHE R CD1 1 
ATOM   8911 C CD2 . PHE E 5 312 ? 114.370 98.937  109.870 1.00 91.89  ?  312 PHE R CD2 1 
ATOM   8912 C CE1 . PHE E 5 312 ? 111.970 98.196  108.746 1.00 91.89  ?  312 PHE R CE1 1 
ATOM   8913 C CE2 . PHE E 5 312 ? 114.240 97.695  109.283 1.00 91.89  ?  312 PHE R CE2 1 
ATOM   8914 C CZ  . PHE E 5 312 ? 113.039 97.323  108.719 1.00 91.89  ?  312 PHE R CZ  1 
ATOM   8915 N N   . LYS E 5 313 ? 114.986 100.299 113.267 1.00 93.60  ?  313 LYS R N   1 
ATOM   8916 C CA  . LYS E 5 313 ? 115.609 99.213  114.014 1.00 93.60  ?  313 LYS R CA  1 
ATOM   8917 C C   . LYS E 5 313 ? 114.864 98.885  115.300 1.00 93.60  ?  313 LYS R C   1 
ATOM   8918 O O   . LYS E 5 313 ? 115.068 97.798  115.851 1.00 93.60  ?  313 LYS R O   1 
ATOM   8919 C CB  . LYS E 5 313 ? 117.061 99.569  114.338 1.00 93.60  ?  313 LYS R CB  1 
ATOM   8920 C CG  . LYS E 5 313 ? 117.996 99.508  113.140 1.00 93.60  ?  313 LYS R CG  1 
ATOM   8921 C CD  . LYS E 5 313 ? 119.322 100.200 113.422 1.00 93.60  ?  313 LYS R CD  1 
ATOM   8922 C CE  . LYS E 5 313 ? 120.056 99.571  114.597 1.00 93.60  ?  313 LYS R CE  1 
ATOM   8923 N NZ  . LYS E 5 313 ? 121.383 100.206 114.826 1.00 93.60  1  313 LYS R NZ  1 
ATOM   8924 N N   . ASP E 5 314 ? 114.014 99.788  115.789 1.00 93.17  ?  314 ASP R N   1 
ATOM   8925 C CA  . ASP E 5 314 ? 113.167 99.499  116.939 1.00 93.17  ?  314 ASP R CA  1 
ATOM   8926 C C   . ASP E 5 314 ? 111.898 98.766  116.525 1.00 93.17  ?  314 ASP R C   1 
ATOM   8927 O O   . ASP E 5 314 ? 111.500 97.794  117.178 1.00 93.17  ?  314 ASP R O   1 
ATOM   8928 C CB  . ASP E 5 314 ? 112.810 100.796 117.670 1.00 93.17  ?  314 ASP R CB  1 
ATOM   8929 C CG  . ASP E 5 314 ? 114.034 101.530 118.184 1.00 93.17  ?  314 ASP R CG  1 
ATOM   8930 O OD1 . ASP E 5 314 ? 115.160 101.032 117.973 1.00 93.17  ?  314 ASP R OD1 1 
ATOM   8931 O OD2 . ASP E 5 314 ? 113.870 102.604 118.800 1.00 93.17  ?  314 ASP R OD2 1 
ATOM   8932 N N   . ARG E 5 315 ? 111.255 99.220  115.445 1.00 93.41  ?  315 ARG R N   1 
ATOM   8933 C CA  . ARG E 5 315 ? 110.130 98.478  114.890 1.00 93.41  ?  315 ARG R CA  1 
ATOM   8934 C C   . ARG E 5 315 ? 110.546 97.070  114.490 1.00 93.41  ?  315 ARG R C   1 
ATOM   8935 O O   . ARG E 5 315 ? 109.752 96.130  114.603 1.00 93.41  ?  315 ARG R O   1 
ATOM   8936 C CB  . ARG E 5 315 ? 109.559 99.228  113.685 1.00 93.41  ?  315 ARG R CB  1 
ATOM   8937 C CG  . ARG E 5 315 ? 108.181 98.760  113.247 1.00 93.41  ?  315 ARG R CG  1 
ATOM   8938 C CD  . ARG E 5 315 ? 107.825 99.315  111.875 1.00 93.41  ?  315 ARG R CD  1 
ATOM   8939 N NE  . ARG E 5 315 ? 107.897 100.775 111.832 1.00 93.41  ?  315 ARG R NE  1 
ATOM   8940 C CZ  . ARG E 5 315 ? 106.864 101.593 112.018 1.00 93.41  ?  315 ARG R CZ  1 
ATOM   8941 N NH1 . ARG E 5 315 ? 105.652 101.111 112.263 1.00 93.41  1  315 ARG R NH1 1 
ATOM   8942 N NH2 . ARG E 5 315 ? 107.045 102.905 111.956 1.00 93.41  ?  315 ARG R NH2 1 
ATOM   8943 N N   . LEU E 5 316 ? 111.788 96.903  114.030 1.00 94.17  ?  316 LEU R N   1 
ATOM   8944 C CA  . LEU E 5 316 ? 112.285 95.577  113.679 1.00 94.17  ?  316 LEU R CA  1 
ATOM   8945 C C   . LEU E 5 316 ? 112.314 94.665  114.898 1.00 94.17  ?  316 LEU R C   1 
ATOM   8946 O O   . LEU E 5 316 ? 111.755 93.561  114.875 1.00 94.17  ?  316 LEU R O   1 
ATOM   8947 C CB  . LEU E 5 316 ? 113.678 95.695  113.057 1.00 94.17  ?  316 LEU R CB  1 
ATOM   8948 C CG  . LEU E 5 316 ? 114.431 94.391  112.779 1.00 94.17  ?  316 LEU R CG  1 
ATOM   8949 C CD1 . LEU E 5 316 ? 113.668 93.520  111.795 1.00 94.17  ?  316 LEU R CD1 1 
ATOM   8950 C CD2 . LEU E 5 316 ? 115.830 94.686  112.258 1.00 94.17  ?  316 LEU R CD2 1 
ATOM   8951 N N   . LYS E 5 317 ? 112.967 95.107  115.976 1.00 93.75  ?  317 LYS R N   1 
ATOM   8952 C CA  . LYS E 5 317 ? 113.010 94.300  117.190 1.00 93.75  ?  317 LYS R CA  1 
ATOM   8953 C C   . LYS E 5 317 ? 111.614 94.052  117.742 1.00 93.75  ?  317 LYS R C   1 
ATOM   8954 O O   . LYS E 5 317 ? 111.349 92.980  118.298 1.00 93.75  ?  317 LYS R O   1 
ATOM   8955 C CB  . LYS E 5 317 ? 113.884 94.978  118.245 1.00 93.75  ?  317 LYS R CB  1 
ATOM   8956 C CG  . LYS E 5 317 ? 115.351 95.084  117.859 1.00 93.75  ?  317 LYS R CG  1 
ATOM   8957 C CD  . LYS E 5 317 ? 116.219 95.494  119.041 1.00 93.75  ?  317 LYS R CD  1 
ATOM   8958 C CE  . LYS E 5 317 ? 115.855 96.877  119.562 1.00 93.75  ?  317 LYS R CE  1 
ATOM   8959 N NZ  . LYS E 5 317 ? 116.736 97.294  120.688 1.00 93.75  1  317 LYS R NZ  1 
ATOM   8960 N N   . SER E 5 318 ? 110.710 95.023  117.601 1.00 91.04  ?  318 SER R N   1 
ATOM   8961 C CA  . SER E 5 318 ? 109.335 94.816  118.042 1.00 91.04  ?  318 SER R CA  1 
ATOM   8962 C C   . SER E 5 318 ? 108.679 93.687  117.256 1.00 91.04  ?  318 SER R C   1 
ATOM   8963 O O   . SER E 5 318 ? 108.133 92.745  117.840 1.00 91.04  ?  318 SER R O   1 
ATOM   8964 C CB  . SER E 5 318 ? 108.535 96.110  117.893 1.00 91.04  ?  318 SER R CB  1 
ATOM   8965 O OG  . SER E 5 318 ? 108.396 96.467  116.529 1.00 91.04  ?  318 SER R OG  1 
ATOM   8966 N N   . ALA E 5 319 ? 108.729 93.765  115.923 1.00 90.52  ?  319 ALA R N   1 
ATOM   8967 C CA  . ALA E 5 319 ? 108.141 92.718  115.096 1.00 90.52  ?  319 ALA R CA  1 
ATOM   8968 C C   . ALA E 5 319 ? 108.766 91.360  115.382 1.00 90.52  ?  319 ALA R C   1 
ATOM   8969 O O   . ALA E 5 319 ? 108.070 90.338  115.356 1.00 90.52  ?  319 ALA R O   1 
ATOM   8970 C CB  . ALA E 5 319 ? 108.299 93.068  113.616 1.00 90.52  ?  319 ALA R CB  1 
ATOM   8971 N N   . LEU E 5 320 ? 110.071 91.324  115.659 1.00 91.42  ?  320 LEU R N   1 
ATOM   8972 C CA  . LEU E 5 320 ? 110.732 90.057  115.952 1.00 91.42  ?  320 LEU R CA  1 
ATOM   8973 C C   . LEU E 5 320 ? 110.245 89.480  117.276 1.00 91.42  ?  320 LEU R C   1 
ATOM   8974 O O   . LEU E 5 320 ? 109.724 88.360  117.328 1.00 91.42  ?  320 LEU R O   1 
ATOM   8975 C CB  . LEU E 5 320 ? 112.251 90.250  115.975 1.00 91.42  ?  320 LEU R CB  1 
ATOM   8976 C CG  . LEU E 5 320 ? 113.016 89.909  114.692 1.00 91.42  ?  320 LEU R CG  1 
ATOM   8977 C CD1 . LEU E 5 320 ? 112.941 88.417  114.397 1.00 91.42  ?  320 LEU R CD1 1 
ATOM   8978 C CD2 . LEU E 5 320 ? 112.498 90.714  113.510 1.00 91.42  ?  320 LEU R CD2 1 
ATOM   8979 N N   . ARG E 5 321 ? 110.405 90.234  118.359 1.00 89.42  ?  321 ARG R N   1 
ATOM   8980 C CA  . ARG E 5 321 ? 110.039 89.770  119.697 1.00 89.42  ?  321 ARG R CA  1 
ATOM   8981 C C   . ARG E 5 321 ? 108.602 90.144  120.050 1.00 89.42  ?  321 ARG R C   1 
ATOM   8982 O O   . ARG E 5 321 ? 108.334 90.782  121.067 1.00 89.42  ?  321 ARG R O   1 
ATOM   8983 C CB  . ARG E 5 321 ? 111.018 90.334  120.720 1.00 89.42  ?  321 ARG R CB  1 
ATOM   8984 C CG  . ARG E 5 321 ? 112.464 89.932  120.472 1.00 89.42  ?  321 ARG R CG  1 
ATOM   8985 C CD  . ARG E 5 321 ? 113.411 90.610  121.448 1.00 89.42  ?  321 ARG R CD  1 
ATOM   8986 N NE  . ARG E 5 321 ? 114.803 90.244  121.199 1.00 89.42  ?  321 ARG R NE  1 
ATOM   8987 C CZ  . ARG E 5 321 ? 115.841 90.735  121.871 1.00 89.42  ?  321 ARG R CZ  1 
ATOM   8988 N NH1 . ARG E 5 321 ? 115.653 91.621  122.841 1.00 89.42  1  321 ARG R NH1 1 
ATOM   8989 N NH2 . ARG E 5 321 ? 117.070 90.340  121.570 1.00 89.42  ?  321 ARG R NH2 1 
ATOM   8990 N N   . LYS E 5 322 ? 107.661 89.741  119.198 1.00 72.60  ?  322 LYS R N   1 
ATOM   8991 C CA  . LYS E 5 322 ? 106.237 89.975  119.417 1.00 72.60  ?  322 LYS R CA  1 
ATOM   8992 C C   . LYS E 5 322 ? 105.441 88.694  119.601 1.00 72.60  ?  322 LYS R C   1 
ATOM   8993 O O   . LYS E 5 322 ? 104.609 88.617  120.508 1.00 72.60  ?  322 LYS R O   1 
ATOM   8994 C CB  . LYS E 5 322 ? 105.647 90.769  118.245 1.00 72.60  ?  322 LYS R CB  1 
ATOM   8995 C CG  . LYS E 5 322 ? 104.147 91.021  118.349 1.00 72.60  ?  322 LYS R CG  1 
ATOM   8996 C CD  . LYS E 5 322 ? 103.342 90.055  117.490 1.00 72.60  ?  322 LYS R CD  1 
ATOM   8997 C CE  . LYS E 5 322 ? 103.465 90.384  116.008 1.00 72.60  ?  322 LYS R CE  1 
ATOM   8998 N NZ  . LYS E 5 322 ? 102.643 89.475  115.163 1.00 72.60  1  322 LYS R NZ  1 
ATOM   8999 N N   . GLY E 5 323 ? 105.673 87.686  118.766 1.00 60.18  ?  323 GLY R N   1 
ATOM   9000 C CA  . GLY E 5 323 ? 104.955 86.429  118.870 1.00 60.18  ?  323 GLY R CA  1 
ATOM   9001 C C   . GLY E 5 323 ? 105.362 85.434  117.801 1.00 60.18  ?  323 GLY R C   1 
ATOM   9002 O O   . GLY E 5 323 ? 105.594 84.260  118.089 1.00 60.18  ?  323 GLY R O   1 
HETATM 9003 O O2  . LTD F 6 .   ? 118.716 92.516  77.951  1.00 20.00  -1 401 LTD R O2  1 
HETATM 9004 C C1  . LTD F 6 .   ? 117.667 92.758  77.302  1.00 20.00  ?  401 LTD R C1  1 
HETATM 9005 O O1  . LTD F 6 .   ? 117.540 92.295  76.138  1.00 20.00  ?  401 LTD R O1  1 
HETATM 9006 C C2  . LTD F 6 .   ? 116.585 93.589  77.925  1.00 20.00  ?  401 LTD R C2  1 
HETATM 9007 C C3  . LTD F 6 .   ? 115.907 94.737  77.134  1.00 20.00  ?  401 LTD R C3  1 
HETATM 9008 C C4  . LTD F 6 .   ? 116.323 96.211  77.302  1.00 20.00  ?  401 LTD R C4  1 
HETATM 9009 C C5  . LTD F 6 .   ? 117.464 97.058  76.729  1.00 20.00  ?  401 LTD R C5  1 
HETATM 9010 O O3  . LTD F 6 .   ? 118.272 96.250  75.860  1.00 20.00  ?  401 LTD R O3  1 
HETATM 9011 C C6  . LTD F 6 .   ? 118.160 97.898  77.847  1.00 20.00  ?  401 LTD R C6  1 
HETATM 9012 C C7  . LTD F 6 .   ? 117.022 98.569  78.680  1.00 20.00  ?  401 LTD R C7  1 
HETATM 9013 C C8  . LTD F 6 .   ? 116.681 99.843  78.607  1.00 20.00  ?  401 LTD R C8  1 
HETATM 9014 C C9  . LTD F 6 .   ? 115.516 100.269 79.507  1.00 20.00  ?  401 LTD R C9  1 
HETATM 9015 C C10 . LTD F 6 .   ? 114.396 100.781 79.037  1.00 20.00  ?  401 LTD R C10 1 
HETATM 9016 C C11 . LTD F 6 .   ? 113.275 101.133 80.028  1.00 20.00  ?  401 LTD R C11 1 
HETATM 9017 C C12 . LTD F 6 .   ? 112.897 102.339 80.432  1.00 20.00  ?  401 LTD R C12 1 
HETATM 9018 C C13 . LTD F 6 .   ? 113.511 103.676 79.994  1.00 20.00  ?  401 LTD R C13 1 
HETATM 9019 C C14 . LTD F 6 .   ? 112.430 104.596 79.435  1.00 20.00  ?  401 LTD R C14 1 
HETATM 9020 C C15 . LTD F 6 .   ? 111.439 105.182 80.100  1.00 20.00  ?  401 LTD R C15 1 
HETATM 9021 C C16 . LTD F 6 .   ? 111.072 105.069 81.609  1.00 20.00  ?  401 LTD R C16 1 
HETATM 9022 C C17 . LTD F 6 .   ? 110.464 106.275 82.392  1.00 20.00  ?  401 LTD R C17 1 
HETATM 9023 C C18 . LTD F 6 .   ? 109.920 107.474 81.660  1.00 20.00  ?  401 LTD R C18 1 
HETATM 9024 C C19 . LTD F 6 .   ? 110.338 108.832 82.290  1.00 20.00  ?  401 LTD R C19 1 
HETATM 9025 C C20 . LTD F 6 .   ? 109.520 109.998 81.737  1.00 20.00  ?  401 LTD R C20 1 
HETATM 9026 O O32 . LTD F 6 .   ? 123.426 91.269  77.313  1.00 20.00  -1 401 LTD R O32 1 
HETATM 9027 C C21 . LTD F 6 .   ? 124.261 92.201  77.182  1.00 20.00  ?  401 LTD R C21 1 
HETATM 9028 O O31 . LTD F 6 .   ? 125.457 92.160  77.103  1.00 20.00  ?  401 LTD R O31 1 
HETATM 9029 C CA3 . LTD F 6 .   ? 124.036 93.634  77.084  1.00 20.00  ?  401 LTD R CA3 1 
HETATM 9030 N N3  . LTD F 6 .   ? 122.686 93.922  77.270  1.00 20.00  ?  401 LTD R N3  1 
HETATM 9031 C C22 . LTD F 6 .   ? 122.387 95.304  77.124  1.00 20.00  ?  401 LTD R C22 1 
HETATM 9032 O O33 . LTD F 6 .   ? 123.201 96.115  76.826  1.00 20.00  ?  401 LTD R O33 1 
HETATM 9033 C CA2 . LTD F 6 .   ? 120.964 95.663  77.306  1.00 20.00  ?  401 LTD R CA2 1 
HETATM 9034 C CB2 . LTD F 6 .   ? 120.858 97.130  77.683  1.00 20.00  ?  401 LTD R CB2 1 
HETATM 9035 S SG2 . LTD F 6 .   ? 119.456 97.111  78.816  1.00 20.00  ?  401 LTD R SG2 1 
HETATM 9036 N N2  . LTD F 6 .   ? 120.328 95.036  78.451  1.00 20.00  ?  401 LTD R N2  1 
HETATM 9037 H H2  . LTD F 6 .   ? 115.780 92.889  78.119  1.00 20.00  ?  401 LTD R H2  1 
HETATM 9038 H H3  . LTD F 6 .   ? 116.927 93.895  78.901  1.00 20.00  ?  401 LTD R H3  1 
HETATM 9039 H H4  . LTD F 6 .   ? 115.992 94.515  76.078  1.00 20.00  ?  401 LTD R H4  1 
HETATM 9040 H H5  . LTD F 6 .   ? 114.852 94.693  77.383  1.00 20.00  ?  401 LTD R H5  1 
HETATM 9041 H H6  . LTD F 6 .   ? 116.368 96.008  76.239  1.00 20.00  ?  401 LTD R H6  1 
HETATM 9042 H H7  . LTD F 6 .   ? 116.974 95.939  78.027  1.00 20.00  ?  401 LTD R H7  1 
HETATM 9043 H H8  . LTD F 6 .   ? 116.974 97.769  76.114  1.00 20.00  ?  401 LTD R H8  1 
HETATM 9044 H H9  . LTD F 6 .   ? 118.870 96.678  75.209  1.00 20.00  ?  401 LTD R H9  1 
HETATM 9045 H H10 . LTD F 6 .   ? 118.638 98.715  77.325  1.00 20.00  ?  401 LTD R H10 1 
HETATM 9046 H H11 . LTD F 6 .   ? 116.408 97.999  79.340  1.00 20.00  ?  401 LTD R H11 1 
HETATM 9047 H H12 . LTD F 6 .   ? 117.191 100.544 77.963  1.00 20.00  ?  401 LTD R H12 1 
HETATM 9048 H H13 . LTD F 6 .   ? 115.598 100.133 80.574  1.00 20.00  ?  401 LTD R H13 1 
HETATM 9049 H H14 . LTD F 6 .   ? 114.257 100.921 77.973  1.00 20.00  ?  401 LTD R H14 1 
HETATM 9050 H H15 . LTD F 6 .   ? 112.727 100.297 80.444  1.00 20.00  ?  401 LTD R H15 1 
HETATM 9051 H H16 . LTD F 6 .   ? 112.076 102.366 81.138  1.00 20.00  ?  401 LTD R H16 1 
HETATM 9052 H H17 . LTD F 6 .   ? 113.968 104.189 80.822  1.00 20.00  ?  401 LTD R H17 1 
HETATM 9053 H H18 . LTD F 6 .   ? 114.264 103.530 79.230  1.00 20.00  ?  401 LTD R H18 1 
HETATM 9054 H H19 . LTD F 6 .   ? 112.488 104.812 78.376  1.00 20.00  ?  401 LTD R H19 1 
HETATM 9055 H H20 . LTD F 6 .   ? 110.829 105.767 79.446  1.00 20.00  ?  401 LTD R H20 1 
HETATM 9056 H H21 . LTD F 6 .   ? 111.960 104.781 82.158  1.00 20.00  ?  401 LTD R H21 1 
HETATM 9057 H H22 . LTD F 6 .   ? 110.359 104.255 81.694  1.00 20.00  ?  401 LTD R H22 1 
HETATM 9058 H H23 . LTD F 6 .   ? 111.240 106.618 83.067  1.00 20.00  ?  401 LTD R H23 1 
HETATM 9059 H H24 . LTD F 6 .   ? 109.653 105.883 82.998  1.00 20.00  ?  401 LTD R H24 1 
HETATM 9060 H H25 . LTD F 6 .   ? 110.285 107.587 80.655  1.00 20.00  ?  401 LTD R H25 1 
HETATM 9061 H H26 . LTD F 6 .   ? 108.849 107.496 81.771  1.00 20.00  ?  401 LTD R H26 1 
HETATM 9062 H H27 . LTD F 6 .   ? 111.388 109.008 82.079  1.00 20.00  ?  401 LTD R H27 1 
HETATM 9063 H H28 . LTD F 6 .   ? 110.190 108.791 83.364  1.00 20.00  ?  401 LTD R H28 1 
HETATM 9064 H H29 . LTD F 6 .   ? 110.041 110.929 81.936  1.00 20.00  ?  401 LTD R H29 1 
HETATM 9065 H H30 . LTD F 6 .   ? 109.385 109.882 80.665  1.00 20.00  ?  401 LTD R H30 1 
HETATM 9066 H H31 . LTD F 6 .   ? 108.548 110.017 82.222  1.00 20.00  ?  401 LTD R H31 1 
HETATM 9067 H H33 . LTD F 6 .   ? 124.626 94.107  77.862  1.00 20.00  ?  401 LTD R H33 1 
HETATM 9068 H H34 . LTD F 6 .   ? 124.377 93.949  76.102  1.00 20.00  ?  401 LTD R H34 1 
HETATM 9069 H H35 . LTD F 6 .   ? 122.028 93.207  77.503  1.00 20.00  ?  401 LTD R H35 1 
HETATM 9070 H H36 . LTD F 6 .   ? 120.485 95.388  76.390  1.00 20.00  ?  401 LTD R H36 1 
HETATM 9071 H H37 . LTD F 6 .   ? 120.688 97.737  76.802  1.00 20.00  ?  401 LTD R H37 1 
HETATM 9072 H H38 . LTD F 6 .   ? 121.702 97.505  78.252  1.00 20.00  ?  401 LTD R H38 1 
HETATM 9073 H H39 . LTD F 6 .   ? 120.980 94.910  79.201  1.00 20.00  ?  401 LTD R H39 1 
HETATM 9074 H H40 . LTD F 6 .   ? 119.894 94.174  78.201  1.00 20.00  ?  401 LTD R H40 1 
# 
