data_9INF
# 
_entry.id   9INF 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9INF         pdb_00009inf 10.2210/pdb9inf/pdb 
WWPDB D_1300049169 ?            ?                   
EMDB  EMD-60705    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9INF 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-06 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'cryo-EM structure of human XPR1-KIDINS220-1-432 in addition of phosphate in the closed state' 
_pdbx_database_related.db_id          EMD-60705 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yinyuxin@hsc.pku.edu.cn 
_pdbx_contact_author.name_first         Yuxin 
_pdbx_contact_author.name_last          Yin 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4102-0043 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yin, Y.'   1 0000-0003-4102-0043 
'Zuo, P.'   2 0000-0002-5631-9534 
'Liang, L.' 3 0000-0002-3115-2563 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                2879 
_citation.page_last                 2879 
_citation.title                     
'Synergistic activation of the human phosphate exporter XPR1 by KIDINS220 and inositol pyrophosphate.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-58200-y 
_citation.pdbx_database_id_PubMed   40128258 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zuo, P.'   1 0000-0002-5631-9534 
primary 'Wang, W.'  2 0000-0001-7258-0356 
primary 'Dai, Z.'   3 0000-0002-4005-1297 
primary 'Zheng, J.' 4 ?                   
primary 'Yu, S.'    5 0009-0002-2665-8882 
primary 'Wang, G.'  6 0000-0002-4884-2990 
primary 'Yin, Y.'   7 ?                   
primary 'Liang, L.' 8 0000-0002-3115-2563 
primary 'Yin, Y.'   9 0000-0003-3646-8548 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Solute carrier family 53 member 1'          82673.992 2 ? ? ? ? 
2 non-polymer syn CHOLESTEROL                                  386.654   8 ? ? ? ? 
3 non-polymer syn 1,2-Distearoyl-sn-glycerophosphoethanolamine 748.065   6 ? ? ? ? 
4 non-polymer syn 'PALMITIC ACID'                              256.424   2 ? ? ? ? 
5 non-polymer syn 'ARACHIDONIC ACID'                           304.467   2 ? ? ? ? 
6 water       nat water                                        18.015    6 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Phosphate exporter SLC53A1,Protein SYG1 homolog,Xenotropic and polytropic murine leukemia virus receptor X3,X-receptor,Xenotropic and polytropic retrovirus receptor 1
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANTSRENLYFQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANTSRENLYFQ
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 CHOLESTEROL                                  CLR 
3 1,2-Distearoyl-sn-glycerophosphoethanolamine 3PE 
4 'PALMITIC ACID'                              PLM 
5 'ARACHIDONIC ACID'                           ACD 
6 water                                        HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   PHE n 
1 4   ALA n 
1 5   GLU n 
1 6   HIS n 
1 7   LEU n 
1 8   SER n 
1 9   ALA n 
1 10  HIS n 
1 11  ILE n 
1 12  THR n 
1 13  PRO n 
1 14  GLU n 
1 15  TRP n 
1 16  ARG n 
1 17  LYS n 
1 18  GLN n 
1 19  TYR n 
1 20  ILE n 
1 21  GLN n 
1 22  TYR n 
1 23  GLU n 
1 24  ALA n 
1 25  PHE n 
1 26  LYS n 
1 27  ASP n 
1 28  MET n 
1 29  LEU n 
1 30  TYR n 
1 31  SER n 
1 32  ALA n 
1 33  GLN n 
1 34  ASP n 
1 35  GLN n 
1 36  ALA n 
1 37  PRO n 
1 38  SER n 
1 39  VAL n 
1 40  GLU n 
1 41  VAL n 
1 42  THR n 
1 43  ASP n 
1 44  GLU n 
1 45  ASP n 
1 46  THR n 
1 47  VAL n 
1 48  LYS n 
1 49  ARG n 
1 50  TYR n 
1 51  PHE n 
1 52  ALA n 
1 53  LYS n 
1 54  PHE n 
1 55  GLU n 
1 56  GLU n 
1 57  LYS n 
1 58  PHE n 
1 59  PHE n 
1 60  GLN n 
1 61  THR n 
1 62  CYS n 
1 63  GLU n 
1 64  LYS n 
1 65  GLU n 
1 66  LEU n 
1 67  ALA n 
1 68  LYS n 
1 69  ILE n 
1 70  ASN n 
1 71  THR n 
1 72  PHE n 
1 73  TYR n 
1 74  SER n 
1 75  GLU n 
1 76  LYS n 
1 77  LEU n 
1 78  ALA n 
1 79  GLU n 
1 80  ALA n 
1 81  GLN n 
1 82  ARG n 
1 83  ARG n 
1 84  PHE n 
1 85  ALA n 
1 86  THR n 
1 87  LEU n 
1 88  GLN n 
1 89  ASN n 
1 90  GLU n 
1 91  LEU n 
1 92  GLN n 
1 93  SER n 
1 94  SER n 
1 95  LEU n 
1 96  ASP n 
1 97  ALA n 
1 98  GLN n 
1 99  LYS n 
1 100 GLU n 
1 101 SER n 
1 102 THR n 
1 103 GLY n 
1 104 VAL n 
1 105 THR n 
1 106 THR n 
1 107 LEU n 
1 108 ARG n 
1 109 GLN n 
1 110 ARG n 
1 111 ARG n 
1 112 LYS n 
1 113 PRO n 
1 114 VAL n 
1 115 PHE n 
1 116 HIS n 
1 117 LEU n 
1 118 SER n 
1 119 HIS n 
1 120 GLU n 
1 121 GLU n 
1 122 ARG n 
1 123 VAL n 
1 124 GLN n 
1 125 HIS n 
1 126 ARG n 
1 127 ASN n 
1 128 ILE n 
1 129 LYS n 
1 130 ASP n 
1 131 LEU n 
1 132 LYS n 
1 133 LEU n 
1 134 ALA n 
1 135 PHE n 
1 136 SER n 
1 137 GLU n 
1 138 PHE n 
1 139 TYR n 
1 140 LEU n 
1 141 SER n 
1 142 LEU n 
1 143 ILE n 
1 144 LEU n 
1 145 LEU n 
1 146 GLN n 
1 147 ASN n 
1 148 TYR n 
1 149 GLN n 
1 150 ASN n 
1 151 LEU n 
1 152 ASN n 
1 153 PHE n 
1 154 THR n 
1 155 GLY n 
1 156 PHE n 
1 157 ARG n 
1 158 LYS n 
1 159 ILE n 
1 160 LEU n 
1 161 LYS n 
1 162 LYS n 
1 163 HIS n 
1 164 ASP n 
1 165 LYS n 
1 166 ILE n 
1 167 LEU n 
1 168 GLU n 
1 169 THR n 
1 170 SER n 
1 171 ARG n 
1 172 GLY n 
1 173 ALA n 
1 174 ASP n 
1 175 TRP n 
1 176 ARG n 
1 177 VAL n 
1 178 ALA n 
1 179 HIS n 
1 180 VAL n 
1 181 GLU n 
1 182 VAL n 
1 183 ALA n 
1 184 PRO n 
1 185 PHE n 
1 186 TYR n 
1 187 THR n 
1 188 CYS n 
1 189 LYS n 
1 190 LYS n 
1 191 ILE n 
1 192 ASN n 
1 193 GLN n 
1 194 LEU n 
1 195 ILE n 
1 196 SER n 
1 197 GLU n 
1 198 THR n 
1 199 GLU n 
1 200 ALA n 
1 201 VAL n 
1 202 VAL n 
1 203 THR n 
1 204 ASN n 
1 205 GLU n 
1 206 LEU n 
1 207 GLU n 
1 208 ASP n 
1 209 GLY n 
1 210 ASP n 
1 211 ARG n 
1 212 GLN n 
1 213 LYS n 
1 214 ALA n 
1 215 MET n 
1 216 LYS n 
1 217 ARG n 
1 218 LEU n 
1 219 ARG n 
1 220 VAL n 
1 221 PRO n 
1 222 PRO n 
1 223 LEU n 
1 224 GLY n 
1 225 ALA n 
1 226 ALA n 
1 227 GLN n 
1 228 PRO n 
1 229 ALA n 
1 230 PRO n 
1 231 ALA n 
1 232 TRP n 
1 233 THR n 
1 234 THR n 
1 235 PHE n 
1 236 ARG n 
1 237 VAL n 
1 238 GLY n 
1 239 LEU n 
1 240 PHE n 
1 241 CYS n 
1 242 GLY n 
1 243 ILE n 
1 244 PHE n 
1 245 ILE n 
1 246 VAL n 
1 247 LEU n 
1 248 ASN n 
1 249 ILE n 
1 250 THR n 
1 251 LEU n 
1 252 VAL n 
1 253 LEU n 
1 254 ALA n 
1 255 ALA n 
1 256 VAL n 
1 257 PHE n 
1 258 LYS n 
1 259 LEU n 
1 260 GLU n 
1 261 THR n 
1 262 ASP n 
1 263 ARG n 
1 264 SER n 
1 265 ILE n 
1 266 TRP n 
1 267 PRO n 
1 268 LEU n 
1 269 ILE n 
1 270 ARG n 
1 271 ILE n 
1 272 TYR n 
1 273 ARG n 
1 274 GLY n 
1 275 GLY n 
1 276 PHE n 
1 277 LEU n 
1 278 LEU n 
1 279 ILE n 
1 280 GLU n 
1 281 PHE n 
1 282 LEU n 
1 283 PHE n 
1 284 LEU n 
1 285 LEU n 
1 286 GLY n 
1 287 ILE n 
1 288 ASN n 
1 289 THR n 
1 290 TYR n 
1 291 GLY n 
1 292 TRP n 
1 293 ARG n 
1 294 GLN n 
1 295 ALA n 
1 296 GLY n 
1 297 VAL n 
1 298 ASN n 
1 299 HIS n 
1 300 VAL n 
1 301 LEU n 
1 302 ILE n 
1 303 PHE n 
1 304 GLU n 
1 305 LEU n 
1 306 ASN n 
1 307 PRO n 
1 308 ARG n 
1 309 SER n 
1 310 ASN n 
1 311 LEU n 
1 312 SER n 
1 313 HIS n 
1 314 GLN n 
1 315 HIS n 
1 316 LEU n 
1 317 PHE n 
1 318 GLU n 
1 319 ILE n 
1 320 ALA n 
1 321 GLY n 
1 322 PHE n 
1 323 LEU n 
1 324 GLY n 
1 325 ILE n 
1 326 LEU n 
1 327 TRP n 
1 328 CYS n 
1 329 LEU n 
1 330 SER n 
1 331 LEU n 
1 332 LEU n 
1 333 ALA n 
1 334 CYS n 
1 335 PHE n 
1 336 PHE n 
1 337 ALA n 
1 338 PRO n 
1 339 ILE n 
1 340 SER n 
1 341 VAL n 
1 342 ILE n 
1 343 PRO n 
1 344 THR n 
1 345 TYR n 
1 346 VAL n 
1 347 TYR n 
1 348 PRO n 
1 349 LEU n 
1 350 ALA n 
1 351 LEU n 
1 352 TYR n 
1 353 GLY n 
1 354 PHE n 
1 355 MET n 
1 356 VAL n 
1 357 PHE n 
1 358 PHE n 
1 359 LEU n 
1 360 ILE n 
1 361 ASN n 
1 362 PRO n 
1 363 THR n 
1 364 LYS n 
1 365 THR n 
1 366 PHE n 
1 367 TYR n 
1 368 TYR n 
1 369 LYS n 
1 370 SER n 
1 371 ARG n 
1 372 PHE n 
1 373 TRP n 
1 374 LEU n 
1 375 LEU n 
1 376 LYS n 
1 377 LEU n 
1 378 LEU n 
1 379 PHE n 
1 380 ARG n 
1 381 VAL n 
1 382 PHE n 
1 383 THR n 
1 384 ALA n 
1 385 PRO n 
1 386 PHE n 
1 387 HIS n 
1 388 LYS n 
1 389 VAL n 
1 390 GLY n 
1 391 PHE n 
1 392 ALA n 
1 393 ASP n 
1 394 PHE n 
1 395 TRP n 
1 396 LEU n 
1 397 ALA n 
1 398 ASP n 
1 399 GLN n 
1 400 LEU n 
1 401 ASN n 
1 402 SER n 
1 403 LEU n 
1 404 SER n 
1 405 VAL n 
1 406 ILE n 
1 407 LEU n 
1 408 MET n 
1 409 ASP n 
1 410 LEU n 
1 411 GLU n 
1 412 TYR n 
1 413 MET n 
1 414 ILE n 
1 415 CYS n 
1 416 PHE n 
1 417 TYR n 
1 418 SER n 
1 419 LEU n 
1 420 GLU n 
1 421 LEU n 
1 422 LYS n 
1 423 TRP n 
1 424 ASP n 
1 425 GLU n 
1 426 SER n 
1 427 LYS n 
1 428 GLY n 
1 429 LEU n 
1 430 LEU n 
1 431 PRO n 
1 432 ASN n 
1 433 ASN n 
1 434 SER n 
1 435 GLU n 
1 436 GLU n 
1 437 SER n 
1 438 GLY n 
1 439 ILE n 
1 440 CYS n 
1 441 HIS n 
1 442 LYS n 
1 443 TYR n 
1 444 THR n 
1 445 TYR n 
1 446 GLY n 
1 447 VAL n 
1 448 ARG n 
1 449 ALA n 
1 450 ILE n 
1 451 VAL n 
1 452 GLN n 
1 453 CYS n 
1 454 ILE n 
1 455 PRO n 
1 456 ALA n 
1 457 TRP n 
1 458 LEU n 
1 459 ARG n 
1 460 PHE n 
1 461 ILE n 
1 462 GLN n 
1 463 CYS n 
1 464 LEU n 
1 465 ARG n 
1 466 ARG n 
1 467 TYR n 
1 468 ARG n 
1 469 ASP n 
1 470 THR n 
1 471 LYS n 
1 472 ARG n 
1 473 ALA n 
1 474 PHE n 
1 475 PRO n 
1 476 HIS n 
1 477 LEU n 
1 478 VAL n 
1 479 ASN n 
1 480 ALA n 
1 481 GLY n 
1 482 LYS n 
1 483 TYR n 
1 484 SER n 
1 485 THR n 
1 486 THR n 
1 487 PHE n 
1 488 PHE n 
1 489 MET n 
1 490 VAL n 
1 491 THR n 
1 492 PHE n 
1 493 ALA n 
1 494 ALA n 
1 495 LEU n 
1 496 TYR n 
1 497 SER n 
1 498 THR n 
1 499 HIS n 
1 500 LYS n 
1 501 GLU n 
1 502 ARG n 
1 503 GLY n 
1 504 HIS n 
1 505 SER n 
1 506 ASP n 
1 507 THR n 
1 508 MET n 
1 509 VAL n 
1 510 PHE n 
1 511 PHE n 
1 512 TYR n 
1 513 LEU n 
1 514 TRP n 
1 515 ILE n 
1 516 VAL n 
1 517 PHE n 
1 518 TYR n 
1 519 ILE n 
1 520 ILE n 
1 521 SER n 
1 522 SER n 
1 523 CYS n 
1 524 TYR n 
1 525 THR n 
1 526 LEU n 
1 527 ILE n 
1 528 TRP n 
1 529 ASP n 
1 530 LEU n 
1 531 LYS n 
1 532 MET n 
1 533 ASP n 
1 534 TRP n 
1 535 GLY n 
1 536 LEU n 
1 537 PHE n 
1 538 ASP n 
1 539 LYS n 
1 540 ASN n 
1 541 ALA n 
1 542 GLY n 
1 543 GLU n 
1 544 ASN n 
1 545 THR n 
1 546 PHE n 
1 547 LEU n 
1 548 ARG n 
1 549 GLU n 
1 550 GLU n 
1 551 ILE n 
1 552 VAL n 
1 553 TYR n 
1 554 PRO n 
1 555 GLN n 
1 556 LYS n 
1 557 ALA n 
1 558 TYR n 
1 559 TYR n 
1 560 TYR n 
1 561 CYS n 
1 562 ALA n 
1 563 ILE n 
1 564 ILE n 
1 565 GLU n 
1 566 ASP n 
1 567 VAL n 
1 568 ILE n 
1 569 LEU n 
1 570 ARG n 
1 571 PHE n 
1 572 ALA n 
1 573 TRP n 
1 574 THR n 
1 575 ILE n 
1 576 GLN n 
1 577 ILE n 
1 578 SER n 
1 579 ILE n 
1 580 THR n 
1 581 SER n 
1 582 THR n 
1 583 THR n 
1 584 LEU n 
1 585 LEU n 
1 586 PRO n 
1 587 HIS n 
1 588 SER n 
1 589 GLY n 
1 590 ASP n 
1 591 ILE n 
1 592 ILE n 
1 593 ALA n 
1 594 THR n 
1 595 VAL n 
1 596 PHE n 
1 597 ALA n 
1 598 PRO n 
1 599 LEU n 
1 600 GLU n 
1 601 VAL n 
1 602 PHE n 
1 603 ARG n 
1 604 ARG n 
1 605 PHE n 
1 606 VAL n 
1 607 TRP n 
1 608 ASN n 
1 609 PHE n 
1 610 PHE n 
1 611 ARG n 
1 612 LEU n 
1 613 GLU n 
1 614 ASN n 
1 615 GLU n 
1 616 HIS n 
1 617 LEU n 
1 618 ASN n 
1 619 ASN n 
1 620 CYS n 
1 621 GLY n 
1 622 GLU n 
1 623 PHE n 
1 624 ARG n 
1 625 ALA n 
1 626 VAL n 
1 627 ARG n 
1 628 ASP n 
1 629 ILE n 
1 630 SER n 
1 631 VAL n 
1 632 ALA n 
1 633 PRO n 
1 634 LEU n 
1 635 ASN n 
1 636 ALA n 
1 637 ASP n 
1 638 ASP n 
1 639 GLN n 
1 640 THR n 
1 641 LEU n 
1 642 LEU n 
1 643 GLU n 
1 644 GLN n 
1 645 MET n 
1 646 MET n 
1 647 ASP n 
1 648 GLN n 
1 649 ASP n 
1 650 ASP n 
1 651 GLY n 
1 652 VAL n 
1 653 ARG n 
1 654 ASN n 
1 655 ARG n 
1 656 GLN n 
1 657 LYS n 
1 658 ASN n 
1 659 ARG n 
1 660 SER n 
1 661 TRP n 
1 662 LYS n 
1 663 TYR n 
1 664 ASN n 
1 665 GLN n 
1 666 SER n 
1 667 ILE n 
1 668 SER n 
1 669 LEU n 
1 670 ARG n 
1 671 ARG n 
1 672 PRO n 
1 673 ARG n 
1 674 LEU n 
1 675 ALA n 
1 676 SER n 
1 677 GLN n 
1 678 SER n 
1 679 LYS n 
1 680 ALA n 
1 681 ARG n 
1 682 ASP n 
1 683 THR n 
1 684 LYS n 
1 685 VAL n 
1 686 LEU n 
1 687 ILE n 
1 688 GLU n 
1 689 ASP n 
1 690 THR n 
1 691 ASP n 
1 692 ASP n 
1 693 GLU n 
1 694 ALA n 
1 695 ASN n 
1 696 THR n 
1 697 SER n 
1 698 ARG n 
1 699 GLU n 
1 700 ASN n 
1 701 LEU n 
1 702 TYR n 
1 703 PHE n 
1 704 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   704 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'XPR1, SLC53A1, SYG1, X3' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
3PE non-polymer         . 1,2-Distearoyl-sn-glycerophosphoethanolamine 
'3-SN-PHOSPHATIDYLETHANOLAMINE; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE' 'C41 H82 N O8 P' 748.065 
ACD non-polymer         . 'ARACHIDONIC ACID'                           ? 'C20 H32 O2'     304.467 
ALA 'L-peptide linking' y ALANINE                                      ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                     ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                   ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                              ? 'C4 H7 N O4'     133.103 
CLR non-polymer         . CHOLESTEROL                                  ? 'C27 H46 O'      386.654 
CYS 'L-peptide linking' y CYSTEINE                                     ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                    ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                              ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                      ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                    ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                        ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                   ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                      ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                       ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                   ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                ? 'C9 H11 N O2'    165.189 
PLM non-polymer         . 'PALMITIC ACID'                              ? 'C16 H32 O2'     256.424 
PRO 'L-peptide linking' y PROLINE                                      ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                       ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                    ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                   ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                     ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                       ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   LYS 2   2   ?   ?   ?   A . n 
A 1 3   PHE 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   GLU 5   5   ?   ?   ?   A . n 
A 1 6   HIS 6   6   ?   ?   ?   A . n 
A 1 7   LEU 7   7   ?   ?   ?   A . n 
A 1 8   SER 8   8   ?   ?   ?   A . n 
A 1 9   ALA 9   9   ?   ?   ?   A . n 
A 1 10  HIS 10  10  ?   ?   ?   A . n 
A 1 11  ILE 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  ?   ?   ?   A . n 
A 1 13  PRO 13  13  ?   ?   ?   A . n 
A 1 14  GLU 14  14  ?   ?   ?   A . n 
A 1 15  TRP 15  15  ?   ?   ?   A . n 
A 1 16  ARG 16  16  ?   ?   ?   A . n 
A 1 17  LYS 17  17  ?   ?   ?   A . n 
A 1 18  GLN 18  18  ?   ?   ?   A . n 
A 1 19  TYR 19  19  ?   ?   ?   A . n 
A 1 20  ILE 20  20  ?   ?   ?   A . n 
A 1 21  GLN 21  21  ?   ?   ?   A . n 
A 1 22  TYR 22  22  ?   ?   ?   A . n 
A 1 23  GLU 23  23  ?   ?   ?   A . n 
A 1 24  ALA 24  24  ?   ?   ?   A . n 
A 1 25  PHE 25  25  ?   ?   ?   A . n 
A 1 26  LYS 26  26  ?   ?   ?   A . n 
A 1 27  ASP 27  27  ?   ?   ?   A . n 
A 1 28  MET 28  28  ?   ?   ?   A . n 
A 1 29  LEU 29  29  ?   ?   ?   A . n 
A 1 30  TYR 30  30  ?   ?   ?   A . n 
A 1 31  SER 31  31  ?   ?   ?   A . n 
A 1 32  ALA 32  32  ?   ?   ?   A . n 
A 1 33  GLN 33  33  ?   ?   ?   A . n 
A 1 34  ASP 34  34  ?   ?   ?   A . n 
A 1 35  GLN 35  35  ?   ?   ?   A . n 
A 1 36  ALA 36  36  ?   ?   ?   A . n 
A 1 37  PRO 37  37  ?   ?   ?   A . n 
A 1 38  SER 38  38  ?   ?   ?   A . n 
A 1 39  VAL 39  39  ?   ?   ?   A . n 
A 1 40  GLU 40  40  ?   ?   ?   A . n 
A 1 41  VAL 41  41  ?   ?   ?   A . n 
A 1 42  THR 42  42  ?   ?   ?   A . n 
A 1 43  ASP 43  43  ?   ?   ?   A . n 
A 1 44  GLU 44  44  ?   ?   ?   A . n 
A 1 45  ASP 45  45  ?   ?   ?   A . n 
A 1 46  THR 46  46  ?   ?   ?   A . n 
A 1 47  VAL 47  47  ?   ?   ?   A . n 
A 1 48  LYS 48  48  ?   ?   ?   A . n 
A 1 49  ARG 49  49  ?   ?   ?   A . n 
A 1 50  TYR 50  50  ?   ?   ?   A . n 
A 1 51  PHE 51  51  ?   ?   ?   A . n 
A 1 52  ALA 52  52  ?   ?   ?   A . n 
A 1 53  LYS 53  53  ?   ?   ?   A . n 
A 1 54  PHE 54  54  ?   ?   ?   A . n 
A 1 55  GLU 55  55  ?   ?   ?   A . n 
A 1 56  GLU 56  56  ?   ?   ?   A . n 
A 1 57  LYS 57  57  ?   ?   ?   A . n 
A 1 58  PHE 58  58  ?   ?   ?   A . n 
A 1 59  PHE 59  59  ?   ?   ?   A . n 
A 1 60  GLN 60  60  ?   ?   ?   A . n 
A 1 61  THR 61  61  ?   ?   ?   A . n 
A 1 62  CYS 62  62  ?   ?   ?   A . n 
A 1 63  GLU 63  63  ?   ?   ?   A . n 
A 1 64  LYS 64  64  ?   ?   ?   A . n 
A 1 65  GLU 65  65  ?   ?   ?   A . n 
A 1 66  LEU 66  66  ?   ?   ?   A . n 
A 1 67  ALA 67  67  ?   ?   ?   A . n 
A 1 68  LYS 68  68  ?   ?   ?   A . n 
A 1 69  ILE 69  69  ?   ?   ?   A . n 
A 1 70  ASN 70  70  ?   ?   ?   A . n 
A 1 71  THR 71  71  ?   ?   ?   A . n 
A 1 72  PHE 72  72  ?   ?   ?   A . n 
A 1 73  TYR 73  73  ?   ?   ?   A . n 
A 1 74  SER 74  74  ?   ?   ?   A . n 
A 1 75  GLU 75  75  ?   ?   ?   A . n 
A 1 76  LYS 76  76  ?   ?   ?   A . n 
A 1 77  LEU 77  77  ?   ?   ?   A . n 
A 1 78  ALA 78  78  ?   ?   ?   A . n 
A 1 79  GLU 79  79  ?   ?   ?   A . n 
A 1 80  ALA 80  80  ?   ?   ?   A . n 
A 1 81  GLN 81  81  ?   ?   ?   A . n 
A 1 82  ARG 82  82  ?   ?   ?   A . n 
A 1 83  ARG 83  83  ?   ?   ?   A . n 
A 1 84  PHE 84  84  ?   ?   ?   A . n 
A 1 85  ALA 85  85  ?   ?   ?   A . n 
A 1 86  THR 86  86  ?   ?   ?   A . n 
A 1 87  LEU 87  87  ?   ?   ?   A . n 
A 1 88  GLN 88  88  ?   ?   ?   A . n 
A 1 89  ASN 89  89  ?   ?   ?   A . n 
A 1 90  GLU 90  90  ?   ?   ?   A . n 
A 1 91  LEU 91  91  ?   ?   ?   A . n 
A 1 92  GLN 92  92  ?   ?   ?   A . n 
A 1 93  SER 93  93  ?   ?   ?   A . n 
A 1 94  SER 94  94  ?   ?   ?   A . n 
A 1 95  LEU 95  95  ?   ?   ?   A . n 
A 1 96  ASP 96  96  ?   ?   ?   A . n 
A 1 97  ALA 97  97  ?   ?   ?   A . n 
A 1 98  GLN 98  98  ?   ?   ?   A . n 
A 1 99  LYS 99  99  ?   ?   ?   A . n 
A 1 100 GLU 100 100 ?   ?   ?   A . n 
A 1 101 SER 101 101 ?   ?   ?   A . n 
A 1 102 THR 102 102 ?   ?   ?   A . n 
A 1 103 GLY 103 103 ?   ?   ?   A . n 
A 1 104 VAL 104 104 ?   ?   ?   A . n 
A 1 105 THR 105 105 ?   ?   ?   A . n 
A 1 106 THR 106 106 ?   ?   ?   A . n 
A 1 107 LEU 107 107 ?   ?   ?   A . n 
A 1 108 ARG 108 108 ?   ?   ?   A . n 
A 1 109 GLN 109 109 ?   ?   ?   A . n 
A 1 110 ARG 110 110 ?   ?   ?   A . n 
A 1 111 ARG 111 111 ?   ?   ?   A . n 
A 1 112 LYS 112 112 ?   ?   ?   A . n 
A 1 113 PRO 113 113 ?   ?   ?   A . n 
A 1 114 VAL 114 114 ?   ?   ?   A . n 
A 1 115 PHE 115 115 ?   ?   ?   A . n 
A 1 116 HIS 116 116 ?   ?   ?   A . n 
A 1 117 LEU 117 117 ?   ?   ?   A . n 
A 1 118 SER 118 118 ?   ?   ?   A . n 
A 1 119 HIS 119 119 ?   ?   ?   A . n 
A 1 120 GLU 120 120 ?   ?   ?   A . n 
A 1 121 GLU 121 121 ?   ?   ?   A . n 
A 1 122 ARG 122 122 ?   ?   ?   A . n 
A 1 123 VAL 123 123 ?   ?   ?   A . n 
A 1 124 GLN 124 124 ?   ?   ?   A . n 
A 1 125 HIS 125 125 ?   ?   ?   A . n 
A 1 126 ARG 126 126 ?   ?   ?   A . n 
A 1 127 ASN 127 127 ?   ?   ?   A . n 
A 1 128 ILE 128 128 ?   ?   ?   A . n 
A 1 129 LYS 129 129 ?   ?   ?   A . n 
A 1 130 ASP 130 130 ?   ?   ?   A . n 
A 1 131 LEU 131 131 ?   ?   ?   A . n 
A 1 132 LYS 132 132 ?   ?   ?   A . n 
A 1 133 LEU 133 133 ?   ?   ?   A . n 
A 1 134 ALA 134 134 ?   ?   ?   A . n 
A 1 135 PHE 135 135 ?   ?   ?   A . n 
A 1 136 SER 136 136 ?   ?   ?   A . n 
A 1 137 GLU 137 137 ?   ?   ?   A . n 
A 1 138 PHE 138 138 ?   ?   ?   A . n 
A 1 139 TYR 139 139 ?   ?   ?   A . n 
A 1 140 LEU 140 140 ?   ?   ?   A . n 
A 1 141 SER 141 141 ?   ?   ?   A . n 
A 1 142 LEU 142 142 ?   ?   ?   A . n 
A 1 143 ILE 143 143 ?   ?   ?   A . n 
A 1 144 LEU 144 144 ?   ?   ?   A . n 
A 1 145 LEU 145 145 ?   ?   ?   A . n 
A 1 146 GLN 146 146 ?   ?   ?   A . n 
A 1 147 ASN 147 147 ?   ?   ?   A . n 
A 1 148 TYR 148 148 ?   ?   ?   A . n 
A 1 149 GLN 149 149 ?   ?   ?   A . n 
A 1 150 ASN 150 150 ?   ?   ?   A . n 
A 1 151 LEU 151 151 ?   ?   ?   A . n 
A 1 152 ASN 152 152 ?   ?   ?   A . n 
A 1 153 PHE 153 153 ?   ?   ?   A . n 
A 1 154 THR 154 154 ?   ?   ?   A . n 
A 1 155 GLY 155 155 ?   ?   ?   A . n 
A 1 156 PHE 156 156 ?   ?   ?   A . n 
A 1 157 ARG 157 157 ?   ?   ?   A . n 
A 1 158 LYS 158 158 ?   ?   ?   A . n 
A 1 159 ILE 159 159 ?   ?   ?   A . n 
A 1 160 LEU 160 160 ?   ?   ?   A . n 
A 1 161 LYS 161 161 ?   ?   ?   A . n 
A 1 162 LYS 162 162 ?   ?   ?   A . n 
A 1 163 HIS 163 163 ?   ?   ?   A . n 
A 1 164 ASP 164 164 ?   ?   ?   A . n 
A 1 165 LYS 165 165 ?   ?   ?   A . n 
A 1 166 ILE 166 166 ?   ?   ?   A . n 
A 1 167 LEU 167 167 ?   ?   ?   A . n 
A 1 168 GLU 168 168 ?   ?   ?   A . n 
A 1 169 THR 169 169 ?   ?   ?   A . n 
A 1 170 SER 170 170 ?   ?   ?   A . n 
A 1 171 ARG 171 171 ?   ?   ?   A . n 
A 1 172 GLY 172 172 ?   ?   ?   A . n 
A 1 173 ALA 173 173 ?   ?   ?   A . n 
A 1 174 ASP 174 174 ?   ?   ?   A . n 
A 1 175 TRP 175 175 ?   ?   ?   A . n 
A 1 176 ARG 176 176 ?   ?   ?   A . n 
A 1 177 VAL 177 177 ?   ?   ?   A . n 
A 1 178 ALA 178 178 ?   ?   ?   A . n 
A 1 179 HIS 179 179 ?   ?   ?   A . n 
A 1 180 VAL 180 180 ?   ?   ?   A . n 
A 1 181 GLU 181 181 ?   ?   ?   A . n 
A 1 182 VAL 182 182 ?   ?   ?   A . n 
A 1 183 ALA 183 183 ?   ?   ?   A . n 
A 1 184 PRO 184 184 ?   ?   ?   A . n 
A 1 185 PHE 185 185 ?   ?   ?   A . n 
A 1 186 TYR 186 186 ?   ?   ?   A . n 
A 1 187 THR 187 187 ?   ?   ?   A . n 
A 1 188 CYS 188 188 ?   ?   ?   A . n 
A 1 189 LYS 189 189 ?   ?   ?   A . n 
A 1 190 LYS 190 190 ?   ?   ?   A . n 
A 1 191 ILE 191 191 ?   ?   ?   A . n 
A 1 192 ASN 192 192 ?   ?   ?   A . n 
A 1 193 GLN 193 193 ?   ?   ?   A . n 
A 1 194 LEU 194 194 ?   ?   ?   A . n 
A 1 195 ILE 195 195 ?   ?   ?   A . n 
A 1 196 SER 196 196 ?   ?   ?   A . n 
A 1 197 GLU 197 197 ?   ?   ?   A . n 
A 1 198 THR 198 198 ?   ?   ?   A . n 
A 1 199 GLU 199 199 ?   ?   ?   A . n 
A 1 200 ALA 200 200 ?   ?   ?   A . n 
A 1 201 VAL 201 201 ?   ?   ?   A . n 
A 1 202 VAL 202 202 ?   ?   ?   A . n 
A 1 203 THR 203 203 ?   ?   ?   A . n 
A 1 204 ASN 204 204 ?   ?   ?   A . n 
A 1 205 GLU 205 205 ?   ?   ?   A . n 
A 1 206 LEU 206 206 ?   ?   ?   A . n 
A 1 207 GLU 207 207 ?   ?   ?   A . n 
A 1 208 ASP 208 208 ?   ?   ?   A . n 
A 1 209 GLY 209 209 ?   ?   ?   A . n 
A 1 210 ASP 210 210 ?   ?   ?   A . n 
A 1 211 ARG 211 211 ?   ?   ?   A . n 
A 1 212 GLN 212 212 ?   ?   ?   A . n 
A 1 213 LYS 213 213 ?   ?   ?   A . n 
A 1 214 ALA 214 214 ?   ?   ?   A . n 
A 1 215 MET 215 215 ?   ?   ?   A . n 
A 1 216 LYS 216 216 ?   ?   ?   A . n 
A 1 217 ARG 217 217 ?   ?   ?   A . n 
A 1 218 LEU 218 218 ?   ?   ?   A . n 
A 1 219 ARG 219 219 ?   ?   ?   A . n 
A 1 220 VAL 220 220 ?   ?   ?   A . n 
A 1 221 PRO 221 221 ?   ?   ?   A . n 
A 1 222 PRO 222 222 ?   ?   ?   A . n 
A 1 223 LEU 223 223 ?   ?   ?   A . n 
A 1 224 GLY 224 224 ?   ?   ?   A . n 
A 1 225 ALA 225 225 ?   ?   ?   A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 PRO 228 228 228 PRO PRO A . n 
A 1 229 ALA 229 229 229 ALA ALA A . n 
A 1 230 PRO 230 230 230 PRO PRO A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 TRP 232 232 232 TRP TRP A . n 
A 1 233 THR 233 233 233 THR THR A . n 
A 1 234 THR 234 234 234 THR THR A . n 
A 1 235 PHE 235 235 235 PHE PHE A . n 
A 1 236 ARG 236 236 236 ARG ARG A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 CYS 241 241 241 CYS CYS A . n 
A 1 242 GLY 242 242 242 GLY GLY A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 ILE 249 249 249 ILE ILE A . n 
A 1 250 THR 250 250 250 THR THR A . n 
A 1 251 LEU 251 251 251 LEU LEU A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 VAL 256 256 256 VAL VAL A . n 
A 1 257 PHE 257 257 257 PHE PHE A . n 
A 1 258 LYS 258 258 258 LYS LYS A . n 
A 1 259 LEU 259 259 259 LEU LEU A . n 
A 1 260 GLU 260 260 260 GLU GLU A . n 
A 1 261 THR 261 261 261 THR THR A . n 
A 1 262 ASP 262 262 262 ASP ASP A . n 
A 1 263 ARG 263 263 263 ARG ARG A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 ILE 265 265 265 ILE ILE A . n 
A 1 266 TRP 266 266 266 TRP TRP A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 ARG 270 270 270 ARG ARG A . n 
A 1 271 ILE 271 271 271 ILE ILE A . n 
A 1 272 TYR 272 272 272 TYR TYR A . n 
A 1 273 ARG 273 273 273 ARG ARG A . n 
A 1 274 GLY 274 274 274 GLY GLY A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 PHE 276 276 276 PHE PHE A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 LEU 278 278 278 LEU LEU A . n 
A 1 279 ILE 279 279 279 ILE ILE A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 PHE 283 283 283 PHE PHE A . n 
A 1 284 LEU 284 284 284 LEU LEU A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 GLY 286 286 286 GLY GLY A . n 
A 1 287 ILE 287 287 287 ILE ILE A . n 
A 1 288 ASN 288 288 288 ASN ASN A . n 
A 1 289 THR 289 289 289 THR THR A . n 
A 1 290 TYR 290 290 290 TYR TYR A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 TRP 292 292 292 TRP TRP A . n 
A 1 293 ARG 293 293 293 ARG ARG A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 GLY 296 296 296 GLY GLY A . n 
A 1 297 VAL 297 297 297 VAL VAL A . n 
A 1 298 ASN 298 298 298 ASN ASN A . n 
A 1 299 HIS 299 299 299 HIS HIS A . n 
A 1 300 VAL 300 300 300 VAL VAL A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 ILE 302 302 302 ILE ILE A . n 
A 1 303 PHE 303 303 303 PHE PHE A . n 
A 1 304 GLU 304 304 304 GLU GLU A . n 
A 1 305 LEU 305 305 305 LEU LEU A . n 
A 1 306 ASN 306 306 306 ASN ASN A . n 
A 1 307 PRO 307 307 307 PRO PRO A . n 
A 1 308 ARG 308 308 308 ARG ARG A . n 
A 1 309 SER 309 309 309 SER SER A . n 
A 1 310 ASN 310 310 310 ASN ASN A . n 
A 1 311 LEU 311 311 311 LEU LEU A . n 
A 1 312 SER 312 312 312 SER SER A . n 
A 1 313 HIS 313 313 313 HIS HIS A . n 
A 1 314 GLN 314 314 314 GLN GLN A . n 
A 1 315 HIS 315 315 315 HIS HIS A . n 
A 1 316 LEU 316 316 316 LEU LEU A . n 
A 1 317 PHE 317 317 317 PHE PHE A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 GLY 321 321 321 GLY GLY A . n 
A 1 322 PHE 322 322 322 PHE PHE A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 GLY 324 324 324 GLY GLY A . n 
A 1 325 ILE 325 325 325 ILE ILE A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 TRP 327 327 327 TRP TRP A . n 
A 1 328 CYS 328 328 328 CYS CYS A . n 
A 1 329 LEU 329 329 329 LEU LEU A . n 
A 1 330 SER 330 330 330 SER SER A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 ALA 333 333 333 ALA ALA A . n 
A 1 334 CYS 334 334 334 CYS CYS A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 PRO 338 338 338 PRO PRO A . n 
A 1 339 ILE 339 339 339 ILE ILE A . n 
A 1 340 SER 340 340 340 SER SER A . n 
A 1 341 VAL 341 341 341 VAL VAL A . n 
A 1 342 ILE 342 342 342 ILE ILE A . n 
A 1 343 PRO 343 343 343 PRO PRO A . n 
A 1 344 THR 344 344 344 THR THR A . n 
A 1 345 TYR 345 345 345 TYR TYR A . n 
A 1 346 VAL 346 346 346 VAL VAL A . n 
A 1 347 TYR 347 347 347 TYR TYR A . n 
A 1 348 PRO 348 348 348 PRO PRO A . n 
A 1 349 LEU 349 349 349 LEU LEU A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 TYR 352 352 352 TYR TYR A . n 
A 1 353 GLY 353 353 353 GLY GLY A . n 
A 1 354 PHE 354 354 354 PHE PHE A . n 
A 1 355 MET 355 355 355 MET MET A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 PHE 357 357 357 PHE PHE A . n 
A 1 358 PHE 358 358 358 PHE PHE A . n 
A 1 359 LEU 359 359 359 LEU LEU A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 ASN 361 361 361 ASN ASN A . n 
A 1 362 PRO 362 362 362 PRO PRO A . n 
A 1 363 THR 363 363 363 THR THR A . n 
A 1 364 LYS 364 364 364 LYS LYS A . n 
A 1 365 THR 365 365 365 THR THR A . n 
A 1 366 PHE 366 366 366 PHE PHE A . n 
A 1 367 TYR 367 367 367 TYR TYR A . n 
A 1 368 TYR 368 368 368 TYR TYR A . n 
A 1 369 LYS 369 369 369 LYS LYS A . n 
A 1 370 SER 370 370 370 SER SER A . n 
A 1 371 ARG 371 371 371 ARG ARG A . n 
A 1 372 PHE 372 372 372 PHE PHE A . n 
A 1 373 TRP 373 373 373 TRP TRP A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 LYS 376 376 376 LYS LYS A . n 
A 1 377 LEU 377 377 377 LEU LEU A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 PHE 379 379 379 PHE PHE A . n 
A 1 380 ARG 380 380 380 ARG ARG A . n 
A 1 381 VAL 381 381 381 VAL VAL A . n 
A 1 382 PHE 382 382 382 PHE PHE A . n 
A 1 383 THR 383 383 383 THR THR A . n 
A 1 384 ALA 384 384 384 ALA ALA A . n 
A 1 385 PRO 385 385 385 PRO PRO A . n 
A 1 386 PHE 386 386 386 PHE PHE A . n 
A 1 387 HIS 387 387 387 HIS HIS A . n 
A 1 388 LYS 388 388 388 LYS LYS A . n 
A 1 389 VAL 389 389 389 VAL VAL A . n 
A 1 390 GLY 390 390 390 GLY GLY A . n 
A 1 391 PHE 391 391 391 PHE PHE A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 ASP 393 393 393 ASP ASP A . n 
A 1 394 PHE 394 394 394 PHE PHE A . n 
A 1 395 TRP 395 395 395 TRP TRP A . n 
A 1 396 LEU 396 396 396 LEU LEU A . n 
A 1 397 ALA 397 397 397 ALA ALA A . n 
A 1 398 ASP 398 398 398 ASP ASP A . n 
A 1 399 GLN 399 399 399 GLN GLN A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 ASN 401 401 401 ASN ASN A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 SER 404 404 404 SER SER A . n 
A 1 405 VAL 405 405 405 VAL VAL A . n 
A 1 406 ILE 406 406 406 ILE ILE A . n 
A 1 407 LEU 407 407 407 LEU LEU A . n 
A 1 408 MET 408 408 408 MET MET A . n 
A 1 409 ASP 409 409 409 ASP ASP A . n 
A 1 410 LEU 410 410 410 LEU LEU A . n 
A 1 411 GLU 411 411 411 GLU GLU A . n 
A 1 412 TYR 412 412 412 TYR TYR A . n 
A 1 413 MET 413 413 413 MET MET A . n 
A 1 414 ILE 414 414 414 ILE ILE A . n 
A 1 415 CYS 415 415 415 CYS CYS A . n 
A 1 416 PHE 416 416 416 PHE PHE A . n 
A 1 417 TYR 417 417 417 TYR TYR A . n 
A 1 418 SER 418 418 418 SER SER A . n 
A 1 419 LEU 419 419 419 LEU LEU A . n 
A 1 420 GLU 420 420 420 GLU GLU A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 LYS 422 422 422 LYS LYS A . n 
A 1 423 TRP 423 423 423 TRP TRP A . n 
A 1 424 ASP 424 424 424 ASP ASP A . n 
A 1 425 GLU 425 425 425 GLU GLU A . n 
A 1 426 SER 426 426 426 SER SER A . n 
A 1 427 LYS 427 427 427 LYS LYS A . n 
A 1 428 GLY 428 428 428 GLY GLY A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 LEU 430 430 430 LEU LEU A . n 
A 1 431 PRO 431 431 431 PRO PRO A . n 
A 1 432 ASN 432 432 432 ASN ASN A . n 
A 1 433 ASN 433 433 433 ASN ASN A . n 
A 1 434 SER 434 434 434 SER SER A . n 
A 1 435 GLU 435 435 435 GLU GLU A . n 
A 1 436 GLU 436 436 436 GLU GLU A . n 
A 1 437 SER 437 437 437 SER SER A . n 
A 1 438 GLY 438 438 438 GLY GLY A . n 
A 1 439 ILE 439 439 439 ILE ILE A . n 
A 1 440 CYS 440 440 440 CYS CYS A . n 
A 1 441 HIS 441 441 441 HIS HIS A . n 
A 1 442 LYS 442 442 442 LYS LYS A . n 
A 1 443 TYR 443 443 443 TYR TYR A . n 
A 1 444 THR 444 444 444 THR THR A . n 
A 1 445 TYR 445 445 445 TYR TYR A . n 
A 1 446 GLY 446 446 446 GLY GLY A . n 
A 1 447 VAL 447 447 447 VAL VAL A . n 
A 1 448 ARG 448 448 448 ARG ARG A . n 
A 1 449 ALA 449 449 449 ALA ALA A . n 
A 1 450 ILE 450 450 450 ILE ILE A . n 
A 1 451 VAL 451 451 451 VAL VAL A . n 
A 1 452 GLN 452 452 452 GLN GLN A . n 
A 1 453 CYS 453 453 453 CYS CYS A . n 
A 1 454 ILE 454 454 454 ILE ILE A . n 
A 1 455 PRO 455 455 455 PRO PRO A . n 
A 1 456 ALA 456 456 456 ALA ALA A . n 
A 1 457 TRP 457 457 457 TRP TRP A . n 
A 1 458 LEU 458 458 458 LEU LEU A . n 
A 1 459 ARG 459 459 459 ARG ARG A . n 
A 1 460 PHE 460 460 460 PHE PHE A . n 
A 1 461 ILE 461 461 461 ILE ILE A . n 
A 1 462 GLN 462 462 462 GLN GLN A . n 
A 1 463 CYS 463 463 463 CYS CYS A . n 
A 1 464 LEU 464 464 464 LEU LEU A . n 
A 1 465 ARG 465 465 465 ARG ARG A . n 
A 1 466 ARG 466 466 466 ARG ARG A . n 
A 1 467 TYR 467 467 467 TYR TYR A . n 
A 1 468 ARG 468 468 468 ARG ARG A . n 
A 1 469 ASP 469 469 469 ASP ASP A . n 
A 1 470 THR 470 470 470 THR THR A . n 
A 1 471 LYS 471 471 471 LYS LYS A . n 
A 1 472 ARG 472 472 472 ARG ARG A . n 
A 1 473 ALA 473 473 473 ALA ALA A . n 
A 1 474 PHE 474 474 474 PHE PHE A . n 
A 1 475 PRO 475 475 475 PRO PRO A . n 
A 1 476 HIS 476 476 476 HIS HIS A . n 
A 1 477 LEU 477 477 477 LEU LEU A . n 
A 1 478 VAL 478 478 478 VAL VAL A . n 
A 1 479 ASN 479 479 479 ASN ASN A . n 
A 1 480 ALA 480 480 480 ALA ALA A . n 
A 1 481 GLY 481 481 481 GLY GLY A . n 
A 1 482 LYS 482 482 482 LYS LYS A . n 
A 1 483 TYR 483 483 483 TYR TYR A . n 
A 1 484 SER 484 484 484 SER SER A . n 
A 1 485 THR 485 485 485 THR THR A . n 
A 1 486 THR 486 486 486 THR THR A . n 
A 1 487 PHE 487 487 487 PHE PHE A . n 
A 1 488 PHE 488 488 488 PHE PHE A . n 
A 1 489 MET 489 489 489 MET MET A . n 
A 1 490 VAL 490 490 490 VAL VAL A . n 
A 1 491 THR 491 491 491 THR THR A . n 
A 1 492 PHE 492 492 492 PHE PHE A . n 
A 1 493 ALA 493 493 493 ALA ALA A . n 
A 1 494 ALA 494 494 494 ALA ALA A . n 
A 1 495 LEU 495 495 495 LEU LEU A . n 
A 1 496 TYR 496 496 496 TYR TYR A . n 
A 1 497 SER 497 497 497 SER SER A . n 
A 1 498 THR 498 498 498 THR THR A . n 
A 1 499 HIS 499 499 499 HIS HIS A . n 
A 1 500 LYS 500 500 500 LYS LYS A . n 
A 1 501 GLU 501 501 501 GLU GLU A . n 
A 1 502 ARG 502 502 502 ARG ARG A . n 
A 1 503 GLY 503 503 503 GLY GLY A . n 
A 1 504 HIS 504 504 504 HIS HIS A . n 
A 1 505 SER 505 505 505 SER SER A . n 
A 1 506 ASP 506 506 506 ASP ASP A . n 
A 1 507 THR 507 507 507 THR THR A . n 
A 1 508 MET 508 508 508 MET MET A . n 
A 1 509 VAL 509 509 509 VAL VAL A . n 
A 1 510 PHE 510 510 510 PHE PHE A . n 
A 1 511 PHE 511 511 511 PHE PHE A . n 
A 1 512 TYR 512 512 512 TYR TYR A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 TRP 514 514 514 TRP TRP A . n 
A 1 515 ILE 515 515 515 ILE ILE A . n 
A 1 516 VAL 516 516 516 VAL VAL A . n 
A 1 517 PHE 517 517 517 PHE PHE A . n 
A 1 518 TYR 518 518 518 TYR TYR A . n 
A 1 519 ILE 519 519 519 ILE ILE A . n 
A 1 520 ILE 520 520 520 ILE ILE A . n 
A 1 521 SER 521 521 521 SER SER A . n 
A 1 522 SER 522 522 522 SER SER A . n 
A 1 523 CYS 523 523 523 CYS CYS A . n 
A 1 524 TYR 524 524 524 TYR TYR A . n 
A 1 525 THR 525 525 525 THR THR A . n 
A 1 526 LEU 526 526 526 LEU LEU A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 TRP 528 528 528 TRP TRP A . n 
A 1 529 ASP 529 529 529 ASP ASP A . n 
A 1 530 LEU 530 530 530 LEU LEU A . n 
A 1 531 LYS 531 531 531 LYS LYS A . n 
A 1 532 MET 532 532 532 MET MET A . n 
A 1 533 ASP 533 533 533 ASP ASP A . n 
A 1 534 TRP 534 534 534 TRP TRP A . n 
A 1 535 GLY 535 535 535 GLY GLY A . n 
A 1 536 LEU 536 536 536 LEU LEU A . n 
A 1 537 PHE 537 537 537 PHE PHE A . n 
A 1 538 ASP 538 538 538 ASP ASP A . n 
A 1 539 LYS 539 539 539 LYS LYS A . n 
A 1 540 ASN 540 540 540 ASN ASN A . n 
A 1 541 ALA 541 541 541 ALA ALA A . n 
A 1 542 GLY 542 542 542 GLY GLY A . n 
A 1 543 GLU 543 543 543 GLU GLU A . n 
A 1 544 ASN 544 544 544 ASN ASN A . n 
A 1 545 THR 545 545 545 THR THR A . n 
A 1 546 PHE 546 546 546 PHE PHE A . n 
A 1 547 LEU 547 547 547 LEU LEU A . n 
A 1 548 ARG 548 548 548 ARG ARG A . n 
A 1 549 GLU 549 549 549 GLU GLU A . n 
A 1 550 GLU 550 550 550 GLU GLU A . n 
A 1 551 ILE 551 551 551 ILE ILE A . n 
A 1 552 VAL 552 552 552 VAL VAL A . n 
A 1 553 TYR 553 553 553 TYR TYR A . n 
A 1 554 PRO 554 554 554 PRO PRO A . n 
A 1 555 GLN 555 555 555 GLN GLN A . n 
A 1 556 LYS 556 556 556 LYS LYS A . n 
A 1 557 ALA 557 557 557 ALA ALA A . n 
A 1 558 TYR 558 558 558 TYR TYR A . n 
A 1 559 TYR 559 559 559 TYR TYR A . n 
A 1 560 TYR 560 560 560 TYR TYR A . n 
A 1 561 CYS 561 561 561 CYS CYS A . n 
A 1 562 ALA 562 562 562 ALA ALA A . n 
A 1 563 ILE 563 563 563 ILE ILE A . n 
A 1 564 ILE 564 564 564 ILE ILE A . n 
A 1 565 GLU 565 565 565 GLU GLU A . n 
A 1 566 ASP 566 566 566 ASP ASP A . n 
A 1 567 VAL 567 567 567 VAL VAL A . n 
A 1 568 ILE 568 568 568 ILE ILE A . n 
A 1 569 LEU 569 569 569 LEU LEU A . n 
A 1 570 ARG 570 570 570 ARG ARG A . n 
A 1 571 PHE 571 571 571 PHE PHE A . n 
A 1 572 ALA 572 572 572 ALA ALA A . n 
A 1 573 TRP 573 573 573 TRP TRP A . n 
A 1 574 THR 574 574 574 THR THR A . n 
A 1 575 ILE 575 575 575 ILE ILE A . n 
A 1 576 GLN 576 576 576 GLN GLN A . n 
A 1 577 ILE 577 577 577 ILE ILE A . n 
A 1 578 SER 578 578 578 SER SER A . n 
A 1 579 ILE 579 579 579 ILE ILE A . n 
A 1 580 THR 580 580 580 THR THR A . n 
A 1 581 SER 581 581 581 SER SER A . n 
A 1 582 THR 582 582 582 THR THR A . n 
A 1 583 THR 583 583 583 THR THR A . n 
A 1 584 LEU 584 584 584 LEU LEU A . n 
A 1 585 LEU 585 585 585 LEU LEU A . n 
A 1 586 PRO 586 586 586 PRO PRO A . n 
A 1 587 HIS 587 587 587 HIS HIS A . n 
A 1 588 SER 588 588 588 SER SER A . n 
A 1 589 GLY 589 589 589 GLY GLY A . n 
A 1 590 ASP 590 590 590 ASP ASP A . n 
A 1 591 ILE 591 591 591 ILE ILE A . n 
A 1 592 ILE 592 592 592 ILE ILE A . n 
A 1 593 ALA 593 593 593 ALA ALA A . n 
A 1 594 THR 594 594 594 THR THR A . n 
A 1 595 VAL 595 595 595 VAL VAL A . n 
A 1 596 PHE 596 596 596 PHE PHE A . n 
A 1 597 ALA 597 597 597 ALA ALA A . n 
A 1 598 PRO 598 598 598 PRO PRO A . n 
A 1 599 LEU 599 599 599 LEU LEU A . n 
A 1 600 GLU 600 600 600 GLU GLU A . n 
A 1 601 VAL 601 601 601 VAL VAL A . n 
A 1 602 PHE 602 602 602 PHE PHE A . n 
A 1 603 ARG 603 603 603 ARG ARG A . n 
A 1 604 ARG 604 604 604 ARG ARG A . n 
A 1 605 PHE 605 605 605 PHE PHE A . n 
A 1 606 VAL 606 606 606 VAL VAL A . n 
A 1 607 TRP 607 607 607 TRP TRP A . n 
A 1 608 ASN 608 608 608 ASN ASN A . n 
A 1 609 PHE 609 609 609 PHE PHE A . n 
A 1 610 PHE 610 610 610 PHE PHE A . n 
A 1 611 ARG 611 611 611 ARG ARG A . n 
A 1 612 LEU 612 612 612 LEU LEU A . n 
A 1 613 GLU 613 613 613 GLU GLU A . n 
A 1 614 ASN 614 614 614 ASN ASN A . n 
A 1 615 GLU 615 615 615 GLU GLU A . n 
A 1 616 HIS 616 616 616 HIS HIS A . n 
A 1 617 LEU 617 617 617 LEU LEU A . n 
A 1 618 ASN 618 618 618 ASN ASN A . n 
A 1 619 ASN 619 619 619 ASN ASN A . n 
A 1 620 CYS 620 620 620 CYS CYS A . n 
A 1 621 GLY 621 621 621 GLY GLY A . n 
A 1 622 GLU 622 622 622 GLU GLU A . n 
A 1 623 PHE 623 623 623 PHE PHE A . n 
A 1 624 ARG 624 624 624 ARG ARG A . n 
A 1 625 ALA 625 625 625 ALA ALA A . n 
A 1 626 VAL 626 626 626 VAL VAL A . n 
A 1 627 ARG 627 627 ?   ?   ?   A . n 
A 1 628 ASP 628 628 ?   ?   ?   A . n 
A 1 629 ILE 629 629 ?   ?   ?   A . n 
A 1 630 SER 630 630 ?   ?   ?   A . n 
A 1 631 VAL 631 631 ?   ?   ?   A . n 
A 1 632 ALA 632 632 ?   ?   ?   A . n 
A 1 633 PRO 633 633 ?   ?   ?   A . n 
A 1 634 LEU 634 634 ?   ?   ?   A . n 
A 1 635 ASN 635 635 ?   ?   ?   A . n 
A 1 636 ALA 636 636 ?   ?   ?   A . n 
A 1 637 ASP 637 637 ?   ?   ?   A . n 
A 1 638 ASP 638 638 ?   ?   ?   A . n 
A 1 639 GLN 639 639 ?   ?   ?   A . n 
A 1 640 THR 640 640 ?   ?   ?   A . n 
A 1 641 LEU 641 641 ?   ?   ?   A . n 
A 1 642 LEU 642 642 ?   ?   ?   A . n 
A 1 643 GLU 643 643 ?   ?   ?   A . n 
A 1 644 GLN 644 644 ?   ?   ?   A . n 
A 1 645 MET 645 645 ?   ?   ?   A . n 
A 1 646 MET 646 646 ?   ?   ?   A . n 
A 1 647 ASP 647 647 ?   ?   ?   A . n 
A 1 648 GLN 648 648 ?   ?   ?   A . n 
A 1 649 ASP 649 649 ?   ?   ?   A . n 
A 1 650 ASP 650 650 ?   ?   ?   A . n 
A 1 651 GLY 651 651 ?   ?   ?   A . n 
A 1 652 VAL 652 652 ?   ?   ?   A . n 
A 1 653 ARG 653 653 ?   ?   ?   A . n 
A 1 654 ASN 654 654 ?   ?   ?   A . n 
A 1 655 ARG 655 655 ?   ?   ?   A . n 
A 1 656 GLN 656 656 ?   ?   ?   A . n 
A 1 657 LYS 657 657 ?   ?   ?   A . n 
A 1 658 ASN 658 658 ?   ?   ?   A . n 
A 1 659 ARG 659 659 ?   ?   ?   A . n 
A 1 660 SER 660 660 ?   ?   ?   A . n 
A 1 661 TRP 661 661 ?   ?   ?   A . n 
A 1 662 LYS 662 662 ?   ?   ?   A . n 
A 1 663 TYR 663 663 ?   ?   ?   A . n 
A 1 664 ASN 664 664 ?   ?   ?   A . n 
A 1 665 GLN 665 665 ?   ?   ?   A . n 
A 1 666 SER 666 666 ?   ?   ?   A . n 
A 1 667 ILE 667 667 ?   ?   ?   A . n 
A 1 668 SER 668 668 ?   ?   ?   A . n 
A 1 669 LEU 669 669 ?   ?   ?   A . n 
A 1 670 ARG 670 670 ?   ?   ?   A . n 
A 1 671 ARG 671 671 ?   ?   ?   A . n 
A 1 672 PRO 672 672 ?   ?   ?   A . n 
A 1 673 ARG 673 673 ?   ?   ?   A . n 
A 1 674 LEU 674 674 ?   ?   ?   A . n 
A 1 675 ALA 675 675 ?   ?   ?   A . n 
A 1 676 SER 676 676 ?   ?   ?   A . n 
A 1 677 GLN 677 677 ?   ?   ?   A . n 
A 1 678 SER 678 678 ?   ?   ?   A . n 
A 1 679 LYS 679 679 ?   ?   ?   A . n 
A 1 680 ALA 680 680 ?   ?   ?   A . n 
A 1 681 ARG 681 681 ?   ?   ?   A . n 
A 1 682 ASP 682 682 ?   ?   ?   A . n 
A 1 683 THR 683 683 ?   ?   ?   A . n 
A 1 684 LYS 684 684 ?   ?   ?   A . n 
A 1 685 VAL 685 685 ?   ?   ?   A . n 
A 1 686 LEU 686 686 ?   ?   ?   A . n 
A 1 687 ILE 687 687 ?   ?   ?   A . n 
A 1 688 GLU 688 688 ?   ?   ?   A . n 
A 1 689 ASP 689 689 ?   ?   ?   A . n 
A 1 690 THR 690 690 ?   ?   ?   A . n 
A 1 691 ASP 691 691 ?   ?   ?   A . n 
A 1 692 ASP 692 692 ?   ?   ?   A . n 
A 1 693 GLU 693 693 ?   ?   ?   A . n 
A 1 694 ALA 694 694 ?   ?   ?   A . n 
A 1 695 ASN 695 695 ?   ?   ?   A . n 
A 1 696 THR 696 696 ?   ?   ?   A . n 
A 1 697 SER 697 697 ?   ?   ?   A . n 
A 1 698 ARG 698 698 ?   ?   ?   A . n 
A 1 699 GLU 699 699 ?   ?   ?   A . n 
A 1 700 ASN 700 700 ?   ?   ?   A . n 
A 1 701 LEU 701 701 ?   ?   ?   A . n 
A 1 702 TYR 702 702 ?   ?   ?   A . n 
A 1 703 PHE 703 703 ?   ?   ?   A . n 
A 1 704 GLN 704 704 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   LYS 2   2   ?   ?   ?   B . n 
B 1 3   PHE 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   GLU 5   5   ?   ?   ?   B . n 
B 1 6   HIS 6   6   ?   ?   ?   B . n 
B 1 7   LEU 7   7   ?   ?   ?   B . n 
B 1 8   SER 8   8   ?   ?   ?   B . n 
B 1 9   ALA 9   9   ?   ?   ?   B . n 
B 1 10  HIS 10  10  ?   ?   ?   B . n 
B 1 11  ILE 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  ?   ?   ?   B . n 
B 1 13  PRO 13  13  ?   ?   ?   B . n 
B 1 14  GLU 14  14  ?   ?   ?   B . n 
B 1 15  TRP 15  15  ?   ?   ?   B . n 
B 1 16  ARG 16  16  ?   ?   ?   B . n 
B 1 17  LYS 17  17  ?   ?   ?   B . n 
B 1 18  GLN 18  18  ?   ?   ?   B . n 
B 1 19  TYR 19  19  ?   ?   ?   B . n 
B 1 20  ILE 20  20  ?   ?   ?   B . n 
B 1 21  GLN 21  21  ?   ?   ?   B . n 
B 1 22  TYR 22  22  ?   ?   ?   B . n 
B 1 23  GLU 23  23  ?   ?   ?   B . n 
B 1 24  ALA 24  24  ?   ?   ?   B . n 
B 1 25  PHE 25  25  ?   ?   ?   B . n 
B 1 26  LYS 26  26  ?   ?   ?   B . n 
B 1 27  ASP 27  27  ?   ?   ?   B . n 
B 1 28  MET 28  28  ?   ?   ?   B . n 
B 1 29  LEU 29  29  ?   ?   ?   B . n 
B 1 30  TYR 30  30  ?   ?   ?   B . n 
B 1 31  SER 31  31  ?   ?   ?   B . n 
B 1 32  ALA 32  32  ?   ?   ?   B . n 
B 1 33  GLN 33  33  ?   ?   ?   B . n 
B 1 34  ASP 34  34  ?   ?   ?   B . n 
B 1 35  GLN 35  35  ?   ?   ?   B . n 
B 1 36  ALA 36  36  ?   ?   ?   B . n 
B 1 37  PRO 37  37  ?   ?   ?   B . n 
B 1 38  SER 38  38  ?   ?   ?   B . n 
B 1 39  VAL 39  39  ?   ?   ?   B . n 
B 1 40  GLU 40  40  ?   ?   ?   B . n 
B 1 41  VAL 41  41  ?   ?   ?   B . n 
B 1 42  THR 42  42  ?   ?   ?   B . n 
B 1 43  ASP 43  43  ?   ?   ?   B . n 
B 1 44  GLU 44  44  ?   ?   ?   B . n 
B 1 45  ASP 45  45  ?   ?   ?   B . n 
B 1 46  THR 46  46  ?   ?   ?   B . n 
B 1 47  VAL 47  47  ?   ?   ?   B . n 
B 1 48  LYS 48  48  ?   ?   ?   B . n 
B 1 49  ARG 49  49  ?   ?   ?   B . n 
B 1 50  TYR 50  50  ?   ?   ?   B . n 
B 1 51  PHE 51  51  ?   ?   ?   B . n 
B 1 52  ALA 52  52  ?   ?   ?   B . n 
B 1 53  LYS 53  53  ?   ?   ?   B . n 
B 1 54  PHE 54  54  ?   ?   ?   B . n 
B 1 55  GLU 55  55  ?   ?   ?   B . n 
B 1 56  GLU 56  56  ?   ?   ?   B . n 
B 1 57  LYS 57  57  ?   ?   ?   B . n 
B 1 58  PHE 58  58  ?   ?   ?   B . n 
B 1 59  PHE 59  59  ?   ?   ?   B . n 
B 1 60  GLN 60  60  ?   ?   ?   B . n 
B 1 61  THR 61  61  ?   ?   ?   B . n 
B 1 62  CYS 62  62  ?   ?   ?   B . n 
B 1 63  GLU 63  63  ?   ?   ?   B . n 
B 1 64  LYS 64  64  ?   ?   ?   B . n 
B 1 65  GLU 65  65  ?   ?   ?   B . n 
B 1 66  LEU 66  66  ?   ?   ?   B . n 
B 1 67  ALA 67  67  ?   ?   ?   B . n 
B 1 68  LYS 68  68  ?   ?   ?   B . n 
B 1 69  ILE 69  69  ?   ?   ?   B . n 
B 1 70  ASN 70  70  ?   ?   ?   B . n 
B 1 71  THR 71  71  ?   ?   ?   B . n 
B 1 72  PHE 72  72  ?   ?   ?   B . n 
B 1 73  TYR 73  73  ?   ?   ?   B . n 
B 1 74  SER 74  74  ?   ?   ?   B . n 
B 1 75  GLU 75  75  ?   ?   ?   B . n 
B 1 76  LYS 76  76  ?   ?   ?   B . n 
B 1 77  LEU 77  77  ?   ?   ?   B . n 
B 1 78  ALA 78  78  ?   ?   ?   B . n 
B 1 79  GLU 79  79  ?   ?   ?   B . n 
B 1 80  ALA 80  80  ?   ?   ?   B . n 
B 1 81  GLN 81  81  ?   ?   ?   B . n 
B 1 82  ARG 82  82  ?   ?   ?   B . n 
B 1 83  ARG 83  83  ?   ?   ?   B . n 
B 1 84  PHE 84  84  ?   ?   ?   B . n 
B 1 85  ALA 85  85  ?   ?   ?   B . n 
B 1 86  THR 86  86  ?   ?   ?   B . n 
B 1 87  LEU 87  87  ?   ?   ?   B . n 
B 1 88  GLN 88  88  ?   ?   ?   B . n 
B 1 89  ASN 89  89  ?   ?   ?   B . n 
B 1 90  GLU 90  90  ?   ?   ?   B . n 
B 1 91  LEU 91  91  ?   ?   ?   B . n 
B 1 92  GLN 92  92  ?   ?   ?   B . n 
B 1 93  SER 93  93  ?   ?   ?   B . n 
B 1 94  SER 94  94  ?   ?   ?   B . n 
B 1 95  LEU 95  95  ?   ?   ?   B . n 
B 1 96  ASP 96  96  ?   ?   ?   B . n 
B 1 97  ALA 97  97  ?   ?   ?   B . n 
B 1 98  GLN 98  98  ?   ?   ?   B . n 
B 1 99  LYS 99  99  ?   ?   ?   B . n 
B 1 100 GLU 100 100 ?   ?   ?   B . n 
B 1 101 SER 101 101 ?   ?   ?   B . n 
B 1 102 THR 102 102 ?   ?   ?   B . n 
B 1 103 GLY 103 103 ?   ?   ?   B . n 
B 1 104 VAL 104 104 ?   ?   ?   B . n 
B 1 105 THR 105 105 ?   ?   ?   B . n 
B 1 106 THR 106 106 ?   ?   ?   B . n 
B 1 107 LEU 107 107 ?   ?   ?   B . n 
B 1 108 ARG 108 108 ?   ?   ?   B . n 
B 1 109 GLN 109 109 ?   ?   ?   B . n 
B 1 110 ARG 110 110 ?   ?   ?   B . n 
B 1 111 ARG 111 111 ?   ?   ?   B . n 
B 1 112 LYS 112 112 ?   ?   ?   B . n 
B 1 113 PRO 113 113 ?   ?   ?   B . n 
B 1 114 VAL 114 114 ?   ?   ?   B . n 
B 1 115 PHE 115 115 ?   ?   ?   B . n 
B 1 116 HIS 116 116 ?   ?   ?   B . n 
B 1 117 LEU 117 117 ?   ?   ?   B . n 
B 1 118 SER 118 118 ?   ?   ?   B . n 
B 1 119 HIS 119 119 ?   ?   ?   B . n 
B 1 120 GLU 120 120 ?   ?   ?   B . n 
B 1 121 GLU 121 121 ?   ?   ?   B . n 
B 1 122 ARG 122 122 ?   ?   ?   B . n 
B 1 123 VAL 123 123 ?   ?   ?   B . n 
B 1 124 GLN 124 124 ?   ?   ?   B . n 
B 1 125 HIS 125 125 ?   ?   ?   B . n 
B 1 126 ARG 126 126 ?   ?   ?   B . n 
B 1 127 ASN 127 127 ?   ?   ?   B . n 
B 1 128 ILE 128 128 ?   ?   ?   B . n 
B 1 129 LYS 129 129 ?   ?   ?   B . n 
B 1 130 ASP 130 130 ?   ?   ?   B . n 
B 1 131 LEU 131 131 ?   ?   ?   B . n 
B 1 132 LYS 132 132 ?   ?   ?   B . n 
B 1 133 LEU 133 133 ?   ?   ?   B . n 
B 1 134 ALA 134 134 ?   ?   ?   B . n 
B 1 135 PHE 135 135 ?   ?   ?   B . n 
B 1 136 SER 136 136 ?   ?   ?   B . n 
B 1 137 GLU 137 137 ?   ?   ?   B . n 
B 1 138 PHE 138 138 ?   ?   ?   B . n 
B 1 139 TYR 139 139 ?   ?   ?   B . n 
B 1 140 LEU 140 140 ?   ?   ?   B . n 
B 1 141 SER 141 141 ?   ?   ?   B . n 
B 1 142 LEU 142 142 ?   ?   ?   B . n 
B 1 143 ILE 143 143 ?   ?   ?   B . n 
B 1 144 LEU 144 144 ?   ?   ?   B . n 
B 1 145 LEU 145 145 ?   ?   ?   B . n 
B 1 146 GLN 146 146 ?   ?   ?   B . n 
B 1 147 ASN 147 147 ?   ?   ?   B . n 
B 1 148 TYR 148 148 ?   ?   ?   B . n 
B 1 149 GLN 149 149 ?   ?   ?   B . n 
B 1 150 ASN 150 150 ?   ?   ?   B . n 
B 1 151 LEU 151 151 ?   ?   ?   B . n 
B 1 152 ASN 152 152 ?   ?   ?   B . n 
B 1 153 PHE 153 153 ?   ?   ?   B . n 
B 1 154 THR 154 154 ?   ?   ?   B . n 
B 1 155 GLY 155 155 ?   ?   ?   B . n 
B 1 156 PHE 156 156 ?   ?   ?   B . n 
B 1 157 ARG 157 157 ?   ?   ?   B . n 
B 1 158 LYS 158 158 ?   ?   ?   B . n 
B 1 159 ILE 159 159 ?   ?   ?   B . n 
B 1 160 LEU 160 160 ?   ?   ?   B . n 
B 1 161 LYS 161 161 ?   ?   ?   B . n 
B 1 162 LYS 162 162 ?   ?   ?   B . n 
B 1 163 HIS 163 163 ?   ?   ?   B . n 
B 1 164 ASP 164 164 ?   ?   ?   B . n 
B 1 165 LYS 165 165 ?   ?   ?   B . n 
B 1 166 ILE 166 166 ?   ?   ?   B . n 
B 1 167 LEU 167 167 ?   ?   ?   B . n 
B 1 168 GLU 168 168 ?   ?   ?   B . n 
B 1 169 THR 169 169 ?   ?   ?   B . n 
B 1 170 SER 170 170 ?   ?   ?   B . n 
B 1 171 ARG 171 171 ?   ?   ?   B . n 
B 1 172 GLY 172 172 ?   ?   ?   B . n 
B 1 173 ALA 173 173 ?   ?   ?   B . n 
B 1 174 ASP 174 174 ?   ?   ?   B . n 
B 1 175 TRP 175 175 ?   ?   ?   B . n 
B 1 176 ARG 176 176 ?   ?   ?   B . n 
B 1 177 VAL 177 177 ?   ?   ?   B . n 
B 1 178 ALA 178 178 ?   ?   ?   B . n 
B 1 179 HIS 179 179 ?   ?   ?   B . n 
B 1 180 VAL 180 180 ?   ?   ?   B . n 
B 1 181 GLU 181 181 ?   ?   ?   B . n 
B 1 182 VAL 182 182 ?   ?   ?   B . n 
B 1 183 ALA 183 183 ?   ?   ?   B . n 
B 1 184 PRO 184 184 ?   ?   ?   B . n 
B 1 185 PHE 185 185 ?   ?   ?   B . n 
B 1 186 TYR 186 186 ?   ?   ?   B . n 
B 1 187 THR 187 187 ?   ?   ?   B . n 
B 1 188 CYS 188 188 ?   ?   ?   B . n 
B 1 189 LYS 189 189 ?   ?   ?   B . n 
B 1 190 LYS 190 190 ?   ?   ?   B . n 
B 1 191 ILE 191 191 ?   ?   ?   B . n 
B 1 192 ASN 192 192 ?   ?   ?   B . n 
B 1 193 GLN 193 193 ?   ?   ?   B . n 
B 1 194 LEU 194 194 ?   ?   ?   B . n 
B 1 195 ILE 195 195 ?   ?   ?   B . n 
B 1 196 SER 196 196 ?   ?   ?   B . n 
B 1 197 GLU 197 197 ?   ?   ?   B . n 
B 1 198 THR 198 198 ?   ?   ?   B . n 
B 1 199 GLU 199 199 ?   ?   ?   B . n 
B 1 200 ALA 200 200 ?   ?   ?   B . n 
B 1 201 VAL 201 201 ?   ?   ?   B . n 
B 1 202 VAL 202 202 ?   ?   ?   B . n 
B 1 203 THR 203 203 ?   ?   ?   B . n 
B 1 204 ASN 204 204 ?   ?   ?   B . n 
B 1 205 GLU 205 205 ?   ?   ?   B . n 
B 1 206 LEU 206 206 ?   ?   ?   B . n 
B 1 207 GLU 207 207 ?   ?   ?   B . n 
B 1 208 ASP 208 208 ?   ?   ?   B . n 
B 1 209 GLY 209 209 ?   ?   ?   B . n 
B 1 210 ASP 210 210 ?   ?   ?   B . n 
B 1 211 ARG 211 211 ?   ?   ?   B . n 
B 1 212 GLN 212 212 ?   ?   ?   B . n 
B 1 213 LYS 213 213 ?   ?   ?   B . n 
B 1 214 ALA 214 214 ?   ?   ?   B . n 
B 1 215 MET 215 215 ?   ?   ?   B . n 
B 1 216 LYS 216 216 ?   ?   ?   B . n 
B 1 217 ARG 217 217 ?   ?   ?   B . n 
B 1 218 LEU 218 218 ?   ?   ?   B . n 
B 1 219 ARG 219 219 ?   ?   ?   B . n 
B 1 220 VAL 220 220 ?   ?   ?   B . n 
B 1 221 PRO 221 221 ?   ?   ?   B . n 
B 1 222 PRO 222 222 ?   ?   ?   B . n 
B 1 223 LEU 223 223 ?   ?   ?   B . n 
B 1 224 GLY 224 224 ?   ?   ?   B . n 
B 1 225 ALA 225 225 ?   ?   ?   B . n 
B 1 226 ALA 226 226 226 ALA ALA B . n 
B 1 227 GLN 227 227 227 GLN GLN B . n 
B 1 228 PRO 228 228 228 PRO PRO B . n 
B 1 229 ALA 229 229 229 ALA ALA B . n 
B 1 230 PRO 230 230 230 PRO PRO B . n 
B 1 231 ALA 231 231 231 ALA ALA B . n 
B 1 232 TRP 232 232 232 TRP TRP B . n 
B 1 233 THR 233 233 233 THR THR B . n 
B 1 234 THR 234 234 234 THR THR B . n 
B 1 235 PHE 235 235 235 PHE PHE B . n 
B 1 236 ARG 236 236 236 ARG ARG B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 GLY 238 238 238 GLY GLY B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 PHE 240 240 240 PHE PHE B . n 
B 1 241 CYS 241 241 241 CYS CYS B . n 
B 1 242 GLY 242 242 242 GLY GLY B . n 
B 1 243 ILE 243 243 243 ILE ILE B . n 
B 1 244 PHE 244 244 244 PHE PHE B . n 
B 1 245 ILE 245 245 245 ILE ILE B . n 
B 1 246 VAL 246 246 246 VAL VAL B . n 
B 1 247 LEU 247 247 247 LEU LEU B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 ILE 249 249 249 ILE ILE B . n 
B 1 250 THR 250 250 250 THR THR B . n 
B 1 251 LEU 251 251 251 LEU LEU B . n 
B 1 252 VAL 252 252 252 VAL VAL B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 ALA 254 254 254 ALA ALA B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 VAL 256 256 256 VAL VAL B . n 
B 1 257 PHE 257 257 257 PHE PHE B . n 
B 1 258 LYS 258 258 258 LYS LYS B . n 
B 1 259 LEU 259 259 259 LEU LEU B . n 
B 1 260 GLU 260 260 260 GLU GLU B . n 
B 1 261 THR 261 261 261 THR THR B . n 
B 1 262 ASP 262 262 262 ASP ASP B . n 
B 1 263 ARG 263 263 263 ARG ARG B . n 
B 1 264 SER 264 264 264 SER SER B . n 
B 1 265 ILE 265 265 265 ILE ILE B . n 
B 1 266 TRP 266 266 266 TRP TRP B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 ARG 270 270 270 ARG ARG B . n 
B 1 271 ILE 271 271 271 ILE ILE B . n 
B 1 272 TYR 272 272 272 TYR TYR B . n 
B 1 273 ARG 273 273 273 ARG ARG B . n 
B 1 274 GLY 274 274 274 GLY GLY B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 PHE 276 276 276 PHE PHE B . n 
B 1 277 LEU 277 277 277 LEU LEU B . n 
B 1 278 LEU 278 278 278 LEU LEU B . n 
B 1 279 ILE 279 279 279 ILE ILE B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 PHE 281 281 281 PHE PHE B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 PHE 283 283 283 PHE PHE B . n 
B 1 284 LEU 284 284 284 LEU LEU B . n 
B 1 285 LEU 285 285 285 LEU LEU B . n 
B 1 286 GLY 286 286 286 GLY GLY B . n 
B 1 287 ILE 287 287 287 ILE ILE B . n 
B 1 288 ASN 288 288 288 ASN ASN B . n 
B 1 289 THR 289 289 289 THR THR B . n 
B 1 290 TYR 290 290 290 TYR TYR B . n 
B 1 291 GLY 291 291 291 GLY GLY B . n 
B 1 292 TRP 292 292 292 TRP TRP B . n 
B 1 293 ARG 293 293 293 ARG ARG B . n 
B 1 294 GLN 294 294 294 GLN GLN B . n 
B 1 295 ALA 295 295 295 ALA ALA B . n 
B 1 296 GLY 296 296 296 GLY GLY B . n 
B 1 297 VAL 297 297 297 VAL VAL B . n 
B 1 298 ASN 298 298 298 ASN ASN B . n 
B 1 299 HIS 299 299 299 HIS HIS B . n 
B 1 300 VAL 300 300 300 VAL VAL B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 ILE 302 302 302 ILE ILE B . n 
B 1 303 PHE 303 303 303 PHE PHE B . n 
B 1 304 GLU 304 304 304 GLU GLU B . n 
B 1 305 LEU 305 305 305 LEU LEU B . n 
B 1 306 ASN 306 306 306 ASN ASN B . n 
B 1 307 PRO 307 307 307 PRO PRO B . n 
B 1 308 ARG 308 308 308 ARG ARG B . n 
B 1 309 SER 309 309 309 SER SER B . n 
B 1 310 ASN 310 310 310 ASN ASN B . n 
B 1 311 LEU 311 311 311 LEU LEU B . n 
B 1 312 SER 312 312 312 SER SER B . n 
B 1 313 HIS 313 313 313 HIS HIS B . n 
B 1 314 GLN 314 314 314 GLN GLN B . n 
B 1 315 HIS 315 315 315 HIS HIS B . n 
B 1 316 LEU 316 316 316 LEU LEU B . n 
B 1 317 PHE 317 317 317 PHE PHE B . n 
B 1 318 GLU 318 318 318 GLU GLU B . n 
B 1 319 ILE 319 319 319 ILE ILE B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 GLY 321 321 321 GLY GLY B . n 
B 1 322 PHE 322 322 322 PHE PHE B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 GLY 324 324 324 GLY GLY B . n 
B 1 325 ILE 325 325 325 ILE ILE B . n 
B 1 326 LEU 326 326 326 LEU LEU B . n 
B 1 327 TRP 327 327 327 TRP TRP B . n 
B 1 328 CYS 328 328 328 CYS CYS B . n 
B 1 329 LEU 329 329 329 LEU LEU B . n 
B 1 330 SER 330 330 330 SER SER B . n 
B 1 331 LEU 331 331 331 LEU LEU B . n 
B 1 332 LEU 332 332 332 LEU LEU B . n 
B 1 333 ALA 333 333 333 ALA ALA B . n 
B 1 334 CYS 334 334 334 CYS CYS B . n 
B 1 335 PHE 335 335 335 PHE PHE B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 ALA 337 337 337 ALA ALA B . n 
B 1 338 PRO 338 338 338 PRO PRO B . n 
B 1 339 ILE 339 339 339 ILE ILE B . n 
B 1 340 SER 340 340 340 SER SER B . n 
B 1 341 VAL 341 341 341 VAL VAL B . n 
B 1 342 ILE 342 342 342 ILE ILE B . n 
B 1 343 PRO 343 343 343 PRO PRO B . n 
B 1 344 THR 344 344 344 THR THR B . n 
B 1 345 TYR 345 345 345 TYR TYR B . n 
B 1 346 VAL 346 346 346 VAL VAL B . n 
B 1 347 TYR 347 347 347 TYR TYR B . n 
B 1 348 PRO 348 348 348 PRO PRO B . n 
B 1 349 LEU 349 349 349 LEU LEU B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 LEU 351 351 351 LEU LEU B . n 
B 1 352 TYR 352 352 352 TYR TYR B . n 
B 1 353 GLY 353 353 353 GLY GLY B . n 
B 1 354 PHE 354 354 354 PHE PHE B . n 
B 1 355 MET 355 355 355 MET MET B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 PHE 357 357 357 PHE PHE B . n 
B 1 358 PHE 358 358 358 PHE PHE B . n 
B 1 359 LEU 359 359 359 LEU LEU B . n 
B 1 360 ILE 360 360 360 ILE ILE B . n 
B 1 361 ASN 361 361 361 ASN ASN B . n 
B 1 362 PRO 362 362 362 PRO PRO B . n 
B 1 363 THR 363 363 363 THR THR B . n 
B 1 364 LYS 364 364 364 LYS LYS B . n 
B 1 365 THR 365 365 365 THR THR B . n 
B 1 366 PHE 366 366 366 PHE PHE B . n 
B 1 367 TYR 367 367 367 TYR TYR B . n 
B 1 368 TYR 368 368 368 TYR TYR B . n 
B 1 369 LYS 369 369 369 LYS LYS B . n 
B 1 370 SER 370 370 370 SER SER B . n 
B 1 371 ARG 371 371 371 ARG ARG B . n 
B 1 372 PHE 372 372 372 PHE PHE B . n 
B 1 373 TRP 373 373 373 TRP TRP B . n 
B 1 374 LEU 374 374 374 LEU LEU B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 LYS 376 376 376 LYS LYS B . n 
B 1 377 LEU 377 377 377 LEU LEU B . n 
B 1 378 LEU 378 378 378 LEU LEU B . n 
B 1 379 PHE 379 379 379 PHE PHE B . n 
B 1 380 ARG 380 380 380 ARG ARG B . n 
B 1 381 VAL 381 381 381 VAL VAL B . n 
B 1 382 PHE 382 382 382 PHE PHE B . n 
B 1 383 THR 383 383 383 THR THR B . n 
B 1 384 ALA 384 384 384 ALA ALA B . n 
B 1 385 PRO 385 385 385 PRO PRO B . n 
B 1 386 PHE 386 386 386 PHE PHE B . n 
B 1 387 HIS 387 387 387 HIS HIS B . n 
B 1 388 LYS 388 388 388 LYS LYS B . n 
B 1 389 VAL 389 389 389 VAL VAL B . n 
B 1 390 GLY 390 390 390 GLY GLY B . n 
B 1 391 PHE 391 391 391 PHE PHE B . n 
B 1 392 ALA 392 392 392 ALA ALA B . n 
B 1 393 ASP 393 393 393 ASP ASP B . n 
B 1 394 PHE 394 394 394 PHE PHE B . n 
B 1 395 TRP 395 395 395 TRP TRP B . n 
B 1 396 LEU 396 396 396 LEU LEU B . n 
B 1 397 ALA 397 397 397 ALA ALA B . n 
B 1 398 ASP 398 398 398 ASP ASP B . n 
B 1 399 GLN 399 399 399 GLN GLN B . n 
B 1 400 LEU 400 400 400 LEU LEU B . n 
B 1 401 ASN 401 401 401 ASN ASN B . n 
B 1 402 SER 402 402 402 SER SER B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 SER 404 404 404 SER SER B . n 
B 1 405 VAL 405 405 405 VAL VAL B . n 
B 1 406 ILE 406 406 406 ILE ILE B . n 
B 1 407 LEU 407 407 407 LEU LEU B . n 
B 1 408 MET 408 408 408 MET MET B . n 
B 1 409 ASP 409 409 409 ASP ASP B . n 
B 1 410 LEU 410 410 410 LEU LEU B . n 
B 1 411 GLU 411 411 411 GLU GLU B . n 
B 1 412 TYR 412 412 412 TYR TYR B . n 
B 1 413 MET 413 413 413 MET MET B . n 
B 1 414 ILE 414 414 414 ILE ILE B . n 
B 1 415 CYS 415 415 415 CYS CYS B . n 
B 1 416 PHE 416 416 416 PHE PHE B . n 
B 1 417 TYR 417 417 417 TYR TYR B . n 
B 1 418 SER 418 418 418 SER SER B . n 
B 1 419 LEU 419 419 419 LEU LEU B . n 
B 1 420 GLU 420 420 420 GLU GLU B . n 
B 1 421 LEU 421 421 421 LEU LEU B . n 
B 1 422 LYS 422 422 422 LYS LYS B . n 
B 1 423 TRP 423 423 423 TRP TRP B . n 
B 1 424 ASP 424 424 424 ASP ASP B . n 
B 1 425 GLU 425 425 425 GLU GLU B . n 
B 1 426 SER 426 426 426 SER SER B . n 
B 1 427 LYS 427 427 427 LYS LYS B . n 
B 1 428 GLY 428 428 428 GLY GLY B . n 
B 1 429 LEU 429 429 429 LEU LEU B . n 
B 1 430 LEU 430 430 430 LEU LEU B . n 
B 1 431 PRO 431 431 431 PRO PRO B . n 
B 1 432 ASN 432 432 432 ASN ASN B . n 
B 1 433 ASN 433 433 433 ASN ASN B . n 
B 1 434 SER 434 434 434 SER SER B . n 
B 1 435 GLU 435 435 435 GLU GLU B . n 
B 1 436 GLU 436 436 436 GLU GLU B . n 
B 1 437 SER 437 437 437 SER SER B . n 
B 1 438 GLY 438 438 438 GLY GLY B . n 
B 1 439 ILE 439 439 439 ILE ILE B . n 
B 1 440 CYS 440 440 440 CYS CYS B . n 
B 1 441 HIS 441 441 441 HIS HIS B . n 
B 1 442 LYS 442 442 442 LYS LYS B . n 
B 1 443 TYR 443 443 443 TYR TYR B . n 
B 1 444 THR 444 444 444 THR THR B . n 
B 1 445 TYR 445 445 445 TYR TYR B . n 
B 1 446 GLY 446 446 446 GLY GLY B . n 
B 1 447 VAL 447 447 447 VAL VAL B . n 
B 1 448 ARG 448 448 448 ARG ARG B . n 
B 1 449 ALA 449 449 449 ALA ALA B . n 
B 1 450 ILE 450 450 450 ILE ILE B . n 
B 1 451 VAL 451 451 451 VAL VAL B . n 
B 1 452 GLN 452 452 452 GLN GLN B . n 
B 1 453 CYS 453 453 453 CYS CYS B . n 
B 1 454 ILE 454 454 454 ILE ILE B . n 
B 1 455 PRO 455 455 455 PRO PRO B . n 
B 1 456 ALA 456 456 456 ALA ALA B . n 
B 1 457 TRP 457 457 457 TRP TRP B . n 
B 1 458 LEU 458 458 458 LEU LEU B . n 
B 1 459 ARG 459 459 459 ARG ARG B . n 
B 1 460 PHE 460 460 460 PHE PHE B . n 
B 1 461 ILE 461 461 461 ILE ILE B . n 
B 1 462 GLN 462 462 462 GLN GLN B . n 
B 1 463 CYS 463 463 463 CYS CYS B . n 
B 1 464 LEU 464 464 464 LEU LEU B . n 
B 1 465 ARG 465 465 465 ARG ARG B . n 
B 1 466 ARG 466 466 466 ARG ARG B . n 
B 1 467 TYR 467 467 467 TYR TYR B . n 
B 1 468 ARG 468 468 468 ARG ARG B . n 
B 1 469 ASP 469 469 469 ASP ASP B . n 
B 1 470 THR 470 470 470 THR THR B . n 
B 1 471 LYS 471 471 471 LYS LYS B . n 
B 1 472 ARG 472 472 472 ARG ARG B . n 
B 1 473 ALA 473 473 473 ALA ALA B . n 
B 1 474 PHE 474 474 474 PHE PHE B . n 
B 1 475 PRO 475 475 475 PRO PRO B . n 
B 1 476 HIS 476 476 476 HIS HIS B . n 
B 1 477 LEU 477 477 477 LEU LEU B . n 
B 1 478 VAL 478 478 478 VAL VAL B . n 
B 1 479 ASN 479 479 479 ASN ASN B . n 
B 1 480 ALA 480 480 480 ALA ALA B . n 
B 1 481 GLY 481 481 481 GLY GLY B . n 
B 1 482 LYS 482 482 482 LYS LYS B . n 
B 1 483 TYR 483 483 483 TYR TYR B . n 
B 1 484 SER 484 484 484 SER SER B . n 
B 1 485 THR 485 485 485 THR THR B . n 
B 1 486 THR 486 486 486 THR THR B . n 
B 1 487 PHE 487 487 487 PHE PHE B . n 
B 1 488 PHE 488 488 488 PHE PHE B . n 
B 1 489 MET 489 489 489 MET MET B . n 
B 1 490 VAL 490 490 490 VAL VAL B . n 
B 1 491 THR 491 491 491 THR THR B . n 
B 1 492 PHE 492 492 492 PHE PHE B . n 
B 1 493 ALA 493 493 493 ALA ALA B . n 
B 1 494 ALA 494 494 494 ALA ALA B . n 
B 1 495 LEU 495 495 495 LEU LEU B . n 
B 1 496 TYR 496 496 496 TYR TYR B . n 
B 1 497 SER 497 497 497 SER SER B . n 
B 1 498 THR 498 498 498 THR THR B . n 
B 1 499 HIS 499 499 499 HIS HIS B . n 
B 1 500 LYS 500 500 500 LYS LYS B . n 
B 1 501 GLU 501 501 501 GLU GLU B . n 
B 1 502 ARG 502 502 502 ARG ARG B . n 
B 1 503 GLY 503 503 503 GLY GLY B . n 
B 1 504 HIS 504 504 504 HIS HIS B . n 
B 1 505 SER 505 505 505 SER SER B . n 
B 1 506 ASP 506 506 506 ASP ASP B . n 
B 1 507 THR 507 507 507 THR THR B . n 
B 1 508 MET 508 508 508 MET MET B . n 
B 1 509 VAL 509 509 509 VAL VAL B . n 
B 1 510 PHE 510 510 510 PHE PHE B . n 
B 1 511 PHE 511 511 511 PHE PHE B . n 
B 1 512 TYR 512 512 512 TYR TYR B . n 
B 1 513 LEU 513 513 513 LEU LEU B . n 
B 1 514 TRP 514 514 514 TRP TRP B . n 
B 1 515 ILE 515 515 515 ILE ILE B . n 
B 1 516 VAL 516 516 516 VAL VAL B . n 
B 1 517 PHE 517 517 517 PHE PHE B . n 
B 1 518 TYR 518 518 518 TYR TYR B . n 
B 1 519 ILE 519 519 519 ILE ILE B . n 
B 1 520 ILE 520 520 520 ILE ILE B . n 
B 1 521 SER 521 521 521 SER SER B . n 
B 1 522 SER 522 522 522 SER SER B . n 
B 1 523 CYS 523 523 523 CYS CYS B . n 
B 1 524 TYR 524 524 524 TYR TYR B . n 
B 1 525 THR 525 525 525 THR THR B . n 
B 1 526 LEU 526 526 526 LEU LEU B . n 
B 1 527 ILE 527 527 527 ILE ILE B . n 
B 1 528 TRP 528 528 528 TRP TRP B . n 
B 1 529 ASP 529 529 529 ASP ASP B . n 
B 1 530 LEU 530 530 530 LEU LEU B . n 
B 1 531 LYS 531 531 531 LYS LYS B . n 
B 1 532 MET 532 532 532 MET MET B . n 
B 1 533 ASP 533 533 533 ASP ASP B . n 
B 1 534 TRP 534 534 534 TRP TRP B . n 
B 1 535 GLY 535 535 535 GLY GLY B . n 
B 1 536 LEU 536 536 536 LEU LEU B . n 
B 1 537 PHE 537 537 537 PHE PHE B . n 
B 1 538 ASP 538 538 538 ASP ASP B . n 
B 1 539 LYS 539 539 539 LYS LYS B . n 
B 1 540 ASN 540 540 540 ASN ASN B . n 
B 1 541 ALA 541 541 541 ALA ALA B . n 
B 1 542 GLY 542 542 542 GLY GLY B . n 
B 1 543 GLU 543 543 543 GLU GLU B . n 
B 1 544 ASN 544 544 544 ASN ASN B . n 
B 1 545 THR 545 545 545 THR THR B . n 
B 1 546 PHE 546 546 546 PHE PHE B . n 
B 1 547 LEU 547 547 547 LEU LEU B . n 
B 1 548 ARG 548 548 548 ARG ARG B . n 
B 1 549 GLU 549 549 549 GLU GLU B . n 
B 1 550 GLU 550 550 550 GLU GLU B . n 
B 1 551 ILE 551 551 551 ILE ILE B . n 
B 1 552 VAL 552 552 552 VAL VAL B . n 
B 1 553 TYR 553 553 553 TYR TYR B . n 
B 1 554 PRO 554 554 554 PRO PRO B . n 
B 1 555 GLN 555 555 555 GLN GLN B . n 
B 1 556 LYS 556 556 556 LYS LYS B . n 
B 1 557 ALA 557 557 557 ALA ALA B . n 
B 1 558 TYR 558 558 558 TYR TYR B . n 
B 1 559 TYR 559 559 559 TYR TYR B . n 
B 1 560 TYR 560 560 560 TYR TYR B . n 
B 1 561 CYS 561 561 561 CYS CYS B . n 
B 1 562 ALA 562 562 562 ALA ALA B . n 
B 1 563 ILE 563 563 563 ILE ILE B . n 
B 1 564 ILE 564 564 564 ILE ILE B . n 
B 1 565 GLU 565 565 565 GLU GLU B . n 
B 1 566 ASP 566 566 566 ASP ASP B . n 
B 1 567 VAL 567 567 567 VAL VAL B . n 
B 1 568 ILE 568 568 568 ILE ILE B . n 
B 1 569 LEU 569 569 569 LEU LEU B . n 
B 1 570 ARG 570 570 570 ARG ARG B . n 
B 1 571 PHE 571 571 571 PHE PHE B . n 
B 1 572 ALA 572 572 572 ALA ALA B . n 
B 1 573 TRP 573 573 573 TRP TRP B . n 
B 1 574 THR 574 574 574 THR THR B . n 
B 1 575 ILE 575 575 575 ILE ILE B . n 
B 1 576 GLN 576 576 576 GLN GLN B . n 
B 1 577 ILE 577 577 577 ILE ILE B . n 
B 1 578 SER 578 578 578 SER SER B . n 
B 1 579 ILE 579 579 579 ILE ILE B . n 
B 1 580 THR 580 580 580 THR THR B . n 
B 1 581 SER 581 581 581 SER SER B . n 
B 1 582 THR 582 582 582 THR THR B . n 
B 1 583 THR 583 583 583 THR THR B . n 
B 1 584 LEU 584 584 584 LEU LEU B . n 
B 1 585 LEU 585 585 585 LEU LEU B . n 
B 1 586 PRO 586 586 586 PRO PRO B . n 
B 1 587 HIS 587 587 587 HIS HIS B . n 
B 1 588 SER 588 588 588 SER SER B . n 
B 1 589 GLY 589 589 589 GLY GLY B . n 
B 1 590 ASP 590 590 590 ASP ASP B . n 
B 1 591 ILE 591 591 591 ILE ILE B . n 
B 1 592 ILE 592 592 592 ILE ILE B . n 
B 1 593 ALA 593 593 593 ALA ALA B . n 
B 1 594 THR 594 594 594 THR THR B . n 
B 1 595 VAL 595 595 595 VAL VAL B . n 
B 1 596 PHE 596 596 596 PHE PHE B . n 
B 1 597 ALA 597 597 597 ALA ALA B . n 
B 1 598 PRO 598 598 598 PRO PRO B . n 
B 1 599 LEU 599 599 599 LEU LEU B . n 
B 1 600 GLU 600 600 600 GLU GLU B . n 
B 1 601 VAL 601 601 601 VAL VAL B . n 
B 1 602 PHE 602 602 602 PHE PHE B . n 
B 1 603 ARG 603 603 603 ARG ARG B . n 
B 1 604 ARG 604 604 604 ARG ARG B . n 
B 1 605 PHE 605 605 605 PHE PHE B . n 
B 1 606 VAL 606 606 606 VAL VAL B . n 
B 1 607 TRP 607 607 607 TRP TRP B . n 
B 1 608 ASN 608 608 608 ASN ASN B . n 
B 1 609 PHE 609 609 609 PHE PHE B . n 
B 1 610 PHE 610 610 610 PHE PHE B . n 
B 1 611 ARG 611 611 611 ARG ARG B . n 
B 1 612 LEU 612 612 612 LEU LEU B . n 
B 1 613 GLU 613 613 613 GLU GLU B . n 
B 1 614 ASN 614 614 614 ASN ASN B . n 
B 1 615 GLU 615 615 615 GLU GLU B . n 
B 1 616 HIS 616 616 616 HIS HIS B . n 
B 1 617 LEU 617 617 617 LEU LEU B . n 
B 1 618 ASN 618 618 618 ASN ASN B . n 
B 1 619 ASN 619 619 619 ASN ASN B . n 
B 1 620 CYS 620 620 620 CYS CYS B . n 
B 1 621 GLY 621 621 621 GLY GLY B . n 
B 1 622 GLU 622 622 622 GLU GLU B . n 
B 1 623 PHE 623 623 623 PHE PHE B . n 
B 1 624 ARG 624 624 624 ARG ARG B . n 
B 1 625 ALA 625 625 625 ALA ALA B . n 
B 1 626 VAL 626 626 626 VAL VAL B . n 
B 1 627 ARG 627 627 ?   ?   ?   B . n 
B 1 628 ASP 628 628 ?   ?   ?   B . n 
B 1 629 ILE 629 629 ?   ?   ?   B . n 
B 1 630 SER 630 630 ?   ?   ?   B . n 
B 1 631 VAL 631 631 ?   ?   ?   B . n 
B 1 632 ALA 632 632 ?   ?   ?   B . n 
B 1 633 PRO 633 633 ?   ?   ?   B . n 
B 1 634 LEU 634 634 ?   ?   ?   B . n 
B 1 635 ASN 635 635 ?   ?   ?   B . n 
B 1 636 ALA 636 636 ?   ?   ?   B . n 
B 1 637 ASP 637 637 ?   ?   ?   B . n 
B 1 638 ASP 638 638 ?   ?   ?   B . n 
B 1 639 GLN 639 639 ?   ?   ?   B . n 
B 1 640 THR 640 640 ?   ?   ?   B . n 
B 1 641 LEU 641 641 ?   ?   ?   B . n 
B 1 642 LEU 642 642 ?   ?   ?   B . n 
B 1 643 GLU 643 643 ?   ?   ?   B . n 
B 1 644 GLN 644 644 ?   ?   ?   B . n 
B 1 645 MET 645 645 ?   ?   ?   B . n 
B 1 646 MET 646 646 ?   ?   ?   B . n 
B 1 647 ASP 647 647 ?   ?   ?   B . n 
B 1 648 GLN 648 648 ?   ?   ?   B . n 
B 1 649 ASP 649 649 ?   ?   ?   B . n 
B 1 650 ASP 650 650 ?   ?   ?   B . n 
B 1 651 GLY 651 651 ?   ?   ?   B . n 
B 1 652 VAL 652 652 ?   ?   ?   B . n 
B 1 653 ARG 653 653 ?   ?   ?   B . n 
B 1 654 ASN 654 654 ?   ?   ?   B . n 
B 1 655 ARG 655 655 ?   ?   ?   B . n 
B 1 656 GLN 656 656 ?   ?   ?   B . n 
B 1 657 LYS 657 657 ?   ?   ?   B . n 
B 1 658 ASN 658 658 ?   ?   ?   B . n 
B 1 659 ARG 659 659 ?   ?   ?   B . n 
B 1 660 SER 660 660 ?   ?   ?   B . n 
B 1 661 TRP 661 661 ?   ?   ?   B . n 
B 1 662 LYS 662 662 ?   ?   ?   B . n 
B 1 663 TYR 663 663 ?   ?   ?   B . n 
B 1 664 ASN 664 664 ?   ?   ?   B . n 
B 1 665 GLN 665 665 ?   ?   ?   B . n 
B 1 666 SER 666 666 ?   ?   ?   B . n 
B 1 667 ILE 667 667 ?   ?   ?   B . n 
B 1 668 SER 668 668 ?   ?   ?   B . n 
B 1 669 LEU 669 669 ?   ?   ?   B . n 
B 1 670 ARG 670 670 ?   ?   ?   B . n 
B 1 671 ARG 671 671 ?   ?   ?   B . n 
B 1 672 PRO 672 672 ?   ?   ?   B . n 
B 1 673 ARG 673 673 ?   ?   ?   B . n 
B 1 674 LEU 674 674 ?   ?   ?   B . n 
B 1 675 ALA 675 675 ?   ?   ?   B . n 
B 1 676 SER 676 676 ?   ?   ?   B . n 
B 1 677 GLN 677 677 ?   ?   ?   B . n 
B 1 678 SER 678 678 ?   ?   ?   B . n 
B 1 679 LYS 679 679 ?   ?   ?   B . n 
B 1 680 ALA 680 680 ?   ?   ?   B . n 
B 1 681 ARG 681 681 ?   ?   ?   B . n 
B 1 682 ASP 682 682 ?   ?   ?   B . n 
B 1 683 THR 683 683 ?   ?   ?   B . n 
B 1 684 LYS 684 684 ?   ?   ?   B . n 
B 1 685 VAL 685 685 ?   ?   ?   B . n 
B 1 686 LEU 686 686 ?   ?   ?   B . n 
B 1 687 ILE 687 687 ?   ?   ?   B . n 
B 1 688 GLU 688 688 ?   ?   ?   B . n 
B 1 689 ASP 689 689 ?   ?   ?   B . n 
B 1 690 THR 690 690 ?   ?   ?   B . n 
B 1 691 ASP 691 691 ?   ?   ?   B . n 
B 1 692 ASP 692 692 ?   ?   ?   B . n 
B 1 693 GLU 693 693 ?   ?   ?   B . n 
B 1 694 ALA 694 694 ?   ?   ?   B . n 
B 1 695 ASN 695 695 ?   ?   ?   B . n 
B 1 696 THR 696 696 ?   ?   ?   B . n 
B 1 697 SER 697 697 ?   ?   ?   B . n 
B 1 698 ARG 698 698 ?   ?   ?   B . n 
B 1 699 GLU 699 699 ?   ?   ?   B . n 
B 1 700 ASN 700 700 ?   ?   ?   B . n 
B 1 701 LEU 701 701 ?   ?   ?   B . n 
B 1 702 TYR 702 702 ?   ?   ?   B . n 
B 1 703 PHE 703 703 ?   ?   ?   B . n 
B 1 704 GLN 704 704 ?   ?   ?   B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 3PE ? ? 3PE ? ? 'SUBJECT OF INVESTIGATION' ? 
2 ACD ? ? ACD ? ? 'SUBJECT OF INVESTIGATION' ? 
3 CLR ? ? CLR ? ? 'SUBJECT OF INVESTIGATION' ? 
4 PLM ? ? PLM ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 CLR 1 801 701  CLR CLR A . 
D 3 3PE 1 802 801  3PE 3PE A . 
E 3 3PE 1 803 901  3PE 3PE A . 
F 2 CLR 1 804 1001 CLR CLR A . 
G 2 CLR 1 805 1301 CLR CLR A . 
H 3 3PE 1 806 1701 3PE 3PE A . 
I 2 CLR 1 807 1801 CLR CLR A . 
J 2 CLR 1 808 1901 CLR CLR A . 
K 4 PLM 1 809 2101 PLM PLM A . 
L 5 ACD 1 810 2301 ACD ACD A . 
M 2 CLR 1 801 701  CLR CLR B . 
N 3 3PE 1 802 801  3PE 3PE B . 
O 3 3PE 1 803 901  3PE 3PE B . 
P 2 CLR 1 804 1301 CLR CLR B . 
Q 3 3PE 1 805 1701 3PE 3PE B . 
R 2 CLR 1 806 1801 CLR CLR B . 
S 4 PLM 1 807 2101 PLM PLM B . 
T 5 ACD 1 808 2301 ACD ACD B . 
U 6 HOH 1 901 1    HOH HOH A . 
U 6 HOH 2 902 2    HOH HOH A . 
U 6 HOH 3 903 3    HOH HOH A . 
V 6 HOH 1 901 4    HOH HOH B . 
V 6 HOH 2 902 5    HOH HOH B . 
V 6 HOH 3 903 6    HOH HOH B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9INF 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9INF 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9INF 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9INF 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 7512  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.672  ? 10166 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 17.234 ? 2734  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.043  ? 1094  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1172  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9INF 
_struct.title                        
'Cryo-EM structure of human XPR1 in closed state in the presence of KIDINS220-1-432 and 10 mM KH2PO4' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9INF 
_struct_keywords.text            'SLC53A1, transporter, phosphate, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 2 ? 
G N N 2 ? 
H N N 3 ? 
I N N 2 ? 
J N N 2 ? 
K N N 4 ? 
L N N 5 ? 
M N N 2 ? 
N N N 3 ? 
O N N 3 ? 
P N N 2 ? 
Q N N 3 ? 
R N N 2 ? 
S N N 4 ? 
T N N 5 ? 
U N N 6 ? 
V N N 6 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    S53A1_HUMAN 
_struct_ref.pdbx_db_accession          Q9UBH6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9INF A 1 ? 696 ? Q9UBH6 1 ? 696 ? 1 696 
2 1 9INF B 1 ? 696 ? Q9UBH6 1 ? 696 ? 1 696 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9INF SER A 697 ? UNP Q9UBH6 ? ? 'expression tag' 697 1  
1 9INF ARG A 698 ? UNP Q9UBH6 ? ? 'expression tag' 698 2  
1 9INF GLU A 699 ? UNP Q9UBH6 ? ? 'expression tag' 699 3  
1 9INF ASN A 700 ? UNP Q9UBH6 ? ? 'expression tag' 700 4  
1 9INF LEU A 701 ? UNP Q9UBH6 ? ? 'expression tag' 701 5  
1 9INF TYR A 702 ? UNP Q9UBH6 ? ? 'expression tag' 702 6  
1 9INF PHE A 703 ? UNP Q9UBH6 ? ? 'expression tag' 703 7  
1 9INF GLN A 704 ? UNP Q9UBH6 ? ? 'expression tag' 704 8  
2 9INF SER B 697 ? UNP Q9UBH6 ? ? 'expression tag' 697 9  
2 9INF ARG B 698 ? UNP Q9UBH6 ? ? 'expression tag' 698 10 
2 9INF GLU B 699 ? UNP Q9UBH6 ? ? 'expression tag' 699 11 
2 9INF ASN B 700 ? UNP Q9UBH6 ? ? 'expression tag' 700 12 
2 9INF LEU B 701 ? UNP Q9UBH6 ? ? 'expression tag' 701 13 
2 9INF TYR B 702 ? UNP Q9UBH6 ? ? 'expression tag' 702 14 
2 9INF PHE B 703 ? UNP Q9UBH6 ? ? 'expression tag' 703 15 
2 9INF GLN B 704 ? UNP Q9UBH6 ? ? 'expression tag' 704 16 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 230 ? LYS A 258 ? PRO A 230 LYS A 258 1 ? 29 
HELX_P HELX_P2  AA2 ILE A 265 ? GLY A 296 ? ILE A 265 GLY A 296 1 ? 32 
HELX_P HELX_P3  AA3 ASN A 298 ? GLU A 304 ? ASN A 298 GLU A 304 1 ? 7  
HELX_P HELX_P4  AA4 SER A 312 ? PHE A 336 ? SER A 312 PHE A 336 1 ? 25 
HELX_P HELX_P5  AA5 TYR A 345 ? ASN A 361 ? TYR A 345 ASN A 361 1 ? 17 
HELX_P HELX_P6  AA6 TYR A 367 ? THR A 383 ? TYR A 367 THR A 383 1 ? 17 
HELX_P HELX_P7  AA7 ALA A 384 ? HIS A 387 ? ALA A 384 HIS A 387 5 ? 4  
HELX_P HELX_P8  AA8 GLY A 390 ? SER A 402 ? GLY A 390 SER A 402 1 ? 13 
HELX_P HELX_P9  AA9 LEU A 403 ? GLU A 420 ? LEU A 403 GLU A 420 1 ? 18 
HELX_P HELX_P10 AB1 GLY A 446 ? LYS A 471 ? GLY A 446 LYS A 471 1 ? 26 
HELX_P HELX_P11 AB2 ARG A 472 ? GLY A 503 ? ARG A 472 GLY A 503 1 ? 32 
HELX_P HELX_P12 AB3 ASP A 506 ? MET A 532 ? ASP A 506 MET A 532 1 ? 27 
HELX_P HELX_P13 AB4 ASP A 538 ? GLY A 542 ? ASP A 538 GLY A 542 5 ? 5  
HELX_P HELX_P14 AB5 GLN A 555 ? THR A 580 ? GLN A 555 THR A 580 1 ? 26 
HELX_P HELX_P15 AB6 PRO A 586 ? ASN A 618 ? PRO A 586 ASN A 618 1 ? 33 
HELX_P HELX_P16 AB7 PRO B 230 ? LYS B 258 ? PRO B 230 LYS B 258 1 ? 29 
HELX_P HELX_P17 AB8 ILE B 265 ? GLY B 296 ? ILE B 265 GLY B 296 1 ? 32 
HELX_P HELX_P18 AB9 ASN B 298 ? GLU B 304 ? ASN B 298 GLU B 304 1 ? 7  
HELX_P HELX_P19 AC1 SER B 312 ? PHE B 336 ? SER B 312 PHE B 336 1 ? 25 
HELX_P HELX_P20 AC2 VAL B 346 ? ASN B 361 ? VAL B 346 ASN B 361 1 ? 16 
HELX_P HELX_P21 AC3 TYR B 367 ? THR B 383 ? TYR B 367 THR B 383 1 ? 17 
HELX_P HELX_P22 AC4 ALA B 384 ? HIS B 387 ? ALA B 384 HIS B 387 5 ? 4  
HELX_P HELX_P23 AC5 GLY B 390 ? SER B 402 ? GLY B 390 SER B 402 1 ? 13 
HELX_P HELX_P24 AC6 LEU B 403 ? GLU B 420 ? LEU B 403 GLU B 420 1 ? 18 
HELX_P HELX_P25 AC7 GLY B 446 ? LYS B 471 ? GLY B 446 LYS B 471 1 ? 26 
HELX_P HELX_P26 AC8 ARG B 472 ? ARG B 502 ? ARG B 472 ARG B 502 1 ? 31 
HELX_P HELX_P27 AC9 GLY B 503 ? SER B 505 ? GLY B 503 SER B 505 5 ? 3  
HELX_P HELX_P28 AD1 ASP B 506 ? MET B 532 ? ASP B 506 MET B 532 1 ? 27 
HELX_P HELX_P29 AD2 ASP B 538 ? GLY B 542 ? ASP B 538 GLY B 542 5 ? 5  
HELX_P HELX_P30 AD3 GLN B 555 ? SER B 581 ? GLN B 555 SER B 581 1 ? 27 
HELX_P HELX_P31 AD4 PRO B 586 ? ASN B 618 ? PRO B 586 ASN B 618 1 ? 33 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 415 SG ? ? ? 1_555 A CYS 440 SG ? ? A CYS 415 A CYS 440 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf2 disulf ? ? B CYS 415 SG ? ? ? 1_555 B CYS 440 SG ? ? B CYS 415 B CYS 440 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 415 ? CYS A 440 ? CYS A 415 ? 1_555 CYS A 440 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 415 ? CYS B 440 ? CYS B 415 ? 1_555 CYS B 440 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 474 A . ? PHE 474 A PRO 475 A ? PRO 475 A 1 4.00 
2 PHE 474 B . ? PHE 474 B PRO 475 B ? PRO 475 B 1 1.66 
# 
_pdbx_entry_details.entry_id                   9INF 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 420 ? ? -105.75 42.08   
2 1 SER A 434 ? ? 67.51   -3.82   
3 1 SER A 581 ? ? -102.72 40.34   
4 1 THR A 582 ? ? 37.08   52.02   
5 1 SER B 434 ? ? 68.27   -2.44   
6 1 LEU B 536 ? ? -69.22  -179.28 
7 1 THR B 582 ? ? 36.18   50.31   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9INF 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9INF 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.36 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               230260 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 XPR1-KIDINS220-1-432 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9INF 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9INF 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9INF 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A LYS 2   ? A LYS 2   
3   1 Y 1 A PHE 3   ? A PHE 3   
4   1 Y 1 A ALA 4   ? A ALA 4   
5   1 Y 1 A GLU 5   ? A GLU 5   
6   1 Y 1 A HIS 6   ? A HIS 6   
7   1 Y 1 A LEU 7   ? A LEU 7   
8   1 Y 1 A SER 8   ? A SER 8   
9   1 Y 1 A ALA 9   ? A ALA 9   
10  1 Y 1 A HIS 10  ? A HIS 10  
11  1 Y 1 A ILE 11  ? A ILE 11  
12  1 Y 1 A THR 12  ? A THR 12  
13  1 Y 1 A PRO 13  ? A PRO 13  
14  1 Y 1 A GLU 14  ? A GLU 14  
15  1 Y 1 A TRP 15  ? A TRP 15  
16  1 Y 1 A ARG 16  ? A ARG 16  
17  1 Y 1 A LYS 17  ? A LYS 17  
18  1 Y 1 A GLN 18  ? A GLN 18  
19  1 Y 1 A TYR 19  ? A TYR 19  
20  1 Y 1 A ILE 20  ? A ILE 20  
21  1 Y 1 A GLN 21  ? A GLN 21  
22  1 Y 1 A TYR 22  ? A TYR 22  
23  1 Y 1 A GLU 23  ? A GLU 23  
24  1 Y 1 A ALA 24  ? A ALA 24  
25  1 Y 1 A PHE 25  ? A PHE 25  
26  1 Y 1 A LYS 26  ? A LYS 26  
27  1 Y 1 A ASP 27  ? A ASP 27  
28  1 Y 1 A MET 28  ? A MET 28  
29  1 Y 1 A LEU 29  ? A LEU 29  
30  1 Y 1 A TYR 30  ? A TYR 30  
31  1 Y 1 A SER 31  ? A SER 31  
32  1 Y 1 A ALA 32  ? A ALA 32  
33  1 Y 1 A GLN 33  ? A GLN 33  
34  1 Y 1 A ASP 34  ? A ASP 34  
35  1 Y 1 A GLN 35  ? A GLN 35  
36  1 Y 1 A ALA 36  ? A ALA 36  
37  1 Y 1 A PRO 37  ? A PRO 37  
38  1 Y 1 A SER 38  ? A SER 38  
39  1 Y 1 A VAL 39  ? A VAL 39  
40  1 Y 1 A GLU 40  ? A GLU 40  
41  1 Y 1 A VAL 41  ? A VAL 41  
42  1 Y 1 A THR 42  ? A THR 42  
43  1 Y 1 A ASP 43  ? A ASP 43  
44  1 Y 1 A GLU 44  ? A GLU 44  
45  1 Y 1 A ASP 45  ? A ASP 45  
46  1 Y 1 A THR 46  ? A THR 46  
47  1 Y 1 A VAL 47  ? A VAL 47  
48  1 Y 1 A LYS 48  ? A LYS 48  
49  1 Y 1 A ARG 49  ? A ARG 49  
50  1 Y 1 A TYR 50  ? A TYR 50  
51  1 Y 1 A PHE 51  ? A PHE 51  
52  1 Y 1 A ALA 52  ? A ALA 52  
53  1 Y 1 A LYS 53  ? A LYS 53  
54  1 Y 1 A PHE 54  ? A PHE 54  
55  1 Y 1 A GLU 55  ? A GLU 55  
56  1 Y 1 A GLU 56  ? A GLU 56  
57  1 Y 1 A LYS 57  ? A LYS 57  
58  1 Y 1 A PHE 58  ? A PHE 58  
59  1 Y 1 A PHE 59  ? A PHE 59  
60  1 Y 1 A GLN 60  ? A GLN 60  
61  1 Y 1 A THR 61  ? A THR 61  
62  1 Y 1 A CYS 62  ? A CYS 62  
63  1 Y 1 A GLU 63  ? A GLU 63  
64  1 Y 1 A LYS 64  ? A LYS 64  
65  1 Y 1 A GLU 65  ? A GLU 65  
66  1 Y 1 A LEU 66  ? A LEU 66  
67  1 Y 1 A ALA 67  ? A ALA 67  
68  1 Y 1 A LYS 68  ? A LYS 68  
69  1 Y 1 A ILE 69  ? A ILE 69  
70  1 Y 1 A ASN 70  ? A ASN 70  
71  1 Y 1 A THR 71  ? A THR 71  
72  1 Y 1 A PHE 72  ? A PHE 72  
73  1 Y 1 A TYR 73  ? A TYR 73  
74  1 Y 1 A SER 74  ? A SER 74  
75  1 Y 1 A GLU 75  ? A GLU 75  
76  1 Y 1 A LYS 76  ? A LYS 76  
77  1 Y 1 A LEU 77  ? A LEU 77  
78  1 Y 1 A ALA 78  ? A ALA 78  
79  1 Y 1 A GLU 79  ? A GLU 79  
80  1 Y 1 A ALA 80  ? A ALA 80  
81  1 Y 1 A GLN 81  ? A GLN 81  
82  1 Y 1 A ARG 82  ? A ARG 82  
83  1 Y 1 A ARG 83  ? A ARG 83  
84  1 Y 1 A PHE 84  ? A PHE 84  
85  1 Y 1 A ALA 85  ? A ALA 85  
86  1 Y 1 A THR 86  ? A THR 86  
87  1 Y 1 A LEU 87  ? A LEU 87  
88  1 Y 1 A GLN 88  ? A GLN 88  
89  1 Y 1 A ASN 89  ? A ASN 89  
90  1 Y 1 A GLU 90  ? A GLU 90  
91  1 Y 1 A LEU 91  ? A LEU 91  
92  1 Y 1 A GLN 92  ? A GLN 92  
93  1 Y 1 A SER 93  ? A SER 93  
94  1 Y 1 A SER 94  ? A SER 94  
95  1 Y 1 A LEU 95  ? A LEU 95  
96  1 Y 1 A ASP 96  ? A ASP 96  
97  1 Y 1 A ALA 97  ? A ALA 97  
98  1 Y 1 A GLN 98  ? A GLN 98  
99  1 Y 1 A LYS 99  ? A LYS 99  
100 1 Y 1 A GLU 100 ? A GLU 100 
101 1 Y 1 A SER 101 ? A SER 101 
102 1 Y 1 A THR 102 ? A THR 102 
103 1 Y 1 A GLY 103 ? A GLY 103 
104 1 Y 1 A VAL 104 ? A VAL 104 
105 1 Y 1 A THR 105 ? A THR 105 
106 1 Y 1 A THR 106 ? A THR 106 
107 1 Y 1 A LEU 107 ? A LEU 107 
108 1 Y 1 A ARG 108 ? A ARG 108 
109 1 Y 1 A GLN 109 ? A GLN 109 
110 1 Y 1 A ARG 110 ? A ARG 110 
111 1 Y 1 A ARG 111 ? A ARG 111 
112 1 Y 1 A LYS 112 ? A LYS 112 
113 1 Y 1 A PRO 113 ? A PRO 113 
114 1 Y 1 A VAL 114 ? A VAL 114 
115 1 Y 1 A PHE 115 ? A PHE 115 
116 1 Y 1 A HIS 116 ? A HIS 116 
117 1 Y 1 A LEU 117 ? A LEU 117 
118 1 Y 1 A SER 118 ? A SER 118 
119 1 Y 1 A HIS 119 ? A HIS 119 
120 1 Y 1 A GLU 120 ? A GLU 120 
121 1 Y 1 A GLU 121 ? A GLU 121 
122 1 Y 1 A ARG 122 ? A ARG 122 
123 1 Y 1 A VAL 123 ? A VAL 123 
124 1 Y 1 A GLN 124 ? A GLN 124 
125 1 Y 1 A HIS 125 ? A HIS 125 
126 1 Y 1 A ARG 126 ? A ARG 126 
127 1 Y 1 A ASN 127 ? A ASN 127 
128 1 Y 1 A ILE 128 ? A ILE 128 
129 1 Y 1 A LYS 129 ? A LYS 129 
130 1 Y 1 A ASP 130 ? A ASP 130 
131 1 Y 1 A LEU 131 ? A LEU 131 
132 1 Y 1 A LYS 132 ? A LYS 132 
133 1 Y 1 A LEU 133 ? A LEU 133 
134 1 Y 1 A ALA 134 ? A ALA 134 
135 1 Y 1 A PHE 135 ? A PHE 135 
136 1 Y 1 A SER 136 ? A SER 136 
137 1 Y 1 A GLU 137 ? A GLU 137 
138 1 Y 1 A PHE 138 ? A PHE 138 
139 1 Y 1 A TYR 139 ? A TYR 139 
140 1 Y 1 A LEU 140 ? A LEU 140 
141 1 Y 1 A SER 141 ? A SER 141 
142 1 Y 1 A LEU 142 ? A LEU 142 
143 1 Y 1 A ILE 143 ? A ILE 143 
144 1 Y 1 A LEU 144 ? A LEU 144 
145 1 Y 1 A LEU 145 ? A LEU 145 
146 1 Y 1 A GLN 146 ? A GLN 146 
147 1 Y 1 A ASN 147 ? A ASN 147 
148 1 Y 1 A TYR 148 ? A TYR 148 
149 1 Y 1 A GLN 149 ? A GLN 149 
150 1 Y 1 A ASN 150 ? A ASN 150 
151 1 Y 1 A LEU 151 ? A LEU 151 
152 1 Y 1 A ASN 152 ? A ASN 152 
153 1 Y 1 A PHE 153 ? A PHE 153 
154 1 Y 1 A THR 154 ? A THR 154 
155 1 Y 1 A GLY 155 ? A GLY 155 
156 1 Y 1 A PHE 156 ? A PHE 156 
157 1 Y 1 A ARG 157 ? A ARG 157 
158 1 Y 1 A LYS 158 ? A LYS 158 
159 1 Y 1 A ILE 159 ? A ILE 159 
160 1 Y 1 A LEU 160 ? A LEU 160 
161 1 Y 1 A LYS 161 ? A LYS 161 
162 1 Y 1 A LYS 162 ? A LYS 162 
163 1 Y 1 A HIS 163 ? A HIS 163 
164 1 Y 1 A ASP 164 ? A ASP 164 
165 1 Y 1 A LYS 165 ? A LYS 165 
166 1 Y 1 A ILE 166 ? A ILE 166 
167 1 Y 1 A LEU 167 ? A LEU 167 
168 1 Y 1 A GLU 168 ? A GLU 168 
169 1 Y 1 A THR 169 ? A THR 169 
170 1 Y 1 A SER 170 ? A SER 170 
171 1 Y 1 A ARG 171 ? A ARG 171 
172 1 Y 1 A GLY 172 ? A GLY 172 
173 1 Y 1 A ALA 173 ? A ALA 173 
174 1 Y 1 A ASP 174 ? A ASP 174 
175 1 Y 1 A TRP 175 ? A TRP 175 
176 1 Y 1 A ARG 176 ? A ARG 176 
177 1 Y 1 A VAL 177 ? A VAL 177 
178 1 Y 1 A ALA 178 ? A ALA 178 
179 1 Y 1 A HIS 179 ? A HIS 179 
180 1 Y 1 A VAL 180 ? A VAL 180 
181 1 Y 1 A GLU 181 ? A GLU 181 
182 1 Y 1 A VAL 182 ? A VAL 182 
183 1 Y 1 A ALA 183 ? A ALA 183 
184 1 Y 1 A PRO 184 ? A PRO 184 
185 1 Y 1 A PHE 185 ? A PHE 185 
186 1 Y 1 A TYR 186 ? A TYR 186 
187 1 Y 1 A THR 187 ? A THR 187 
188 1 Y 1 A CYS 188 ? A CYS 188 
189 1 Y 1 A LYS 189 ? A LYS 189 
190 1 Y 1 A LYS 190 ? A LYS 190 
191 1 Y 1 A ILE 191 ? A ILE 191 
192 1 Y 1 A ASN 192 ? A ASN 192 
193 1 Y 1 A GLN 193 ? A GLN 193 
194 1 Y 1 A LEU 194 ? A LEU 194 
195 1 Y 1 A ILE 195 ? A ILE 195 
196 1 Y 1 A SER 196 ? A SER 196 
197 1 Y 1 A GLU 197 ? A GLU 197 
198 1 Y 1 A THR 198 ? A THR 198 
199 1 Y 1 A GLU 199 ? A GLU 199 
200 1 Y 1 A ALA 200 ? A ALA 200 
201 1 Y 1 A VAL 201 ? A VAL 201 
202 1 Y 1 A VAL 202 ? A VAL 202 
203 1 Y 1 A THR 203 ? A THR 203 
204 1 Y 1 A ASN 204 ? A ASN 204 
205 1 Y 1 A GLU 205 ? A GLU 205 
206 1 Y 1 A LEU 206 ? A LEU 206 
207 1 Y 1 A GLU 207 ? A GLU 207 
208 1 Y 1 A ASP 208 ? A ASP 208 
209 1 Y 1 A GLY 209 ? A GLY 209 
210 1 Y 1 A ASP 210 ? A ASP 210 
211 1 Y 1 A ARG 211 ? A ARG 211 
212 1 Y 1 A GLN 212 ? A GLN 212 
213 1 Y 1 A LYS 213 ? A LYS 213 
214 1 Y 1 A ALA 214 ? A ALA 214 
215 1 Y 1 A MET 215 ? A MET 215 
216 1 Y 1 A LYS 216 ? A LYS 216 
217 1 Y 1 A ARG 217 ? A ARG 217 
218 1 Y 1 A LEU 218 ? A LEU 218 
219 1 Y 1 A ARG 219 ? A ARG 219 
220 1 Y 1 A VAL 220 ? A VAL 220 
221 1 Y 1 A PRO 221 ? A PRO 221 
222 1 Y 1 A PRO 222 ? A PRO 222 
223 1 Y 1 A LEU 223 ? A LEU 223 
224 1 Y 1 A GLY 224 ? A GLY 224 
225 1 Y 1 A ALA 225 ? A ALA 225 
226 1 Y 1 A ARG 627 ? A ARG 627 
227 1 Y 1 A ASP 628 ? A ASP 628 
228 1 Y 1 A ILE 629 ? A ILE 629 
229 1 Y 1 A SER 630 ? A SER 630 
230 1 Y 1 A VAL 631 ? A VAL 631 
231 1 Y 1 A ALA 632 ? A ALA 632 
232 1 Y 1 A PRO 633 ? A PRO 633 
233 1 Y 1 A LEU 634 ? A LEU 634 
234 1 Y 1 A ASN 635 ? A ASN 635 
235 1 Y 1 A ALA 636 ? A ALA 636 
236 1 Y 1 A ASP 637 ? A ASP 637 
237 1 Y 1 A ASP 638 ? A ASP 638 
238 1 Y 1 A GLN 639 ? A GLN 639 
239 1 Y 1 A THR 640 ? A THR 640 
240 1 Y 1 A LEU 641 ? A LEU 641 
241 1 Y 1 A LEU 642 ? A LEU 642 
242 1 Y 1 A GLU 643 ? A GLU 643 
243 1 Y 1 A GLN 644 ? A GLN 644 
244 1 Y 1 A MET 645 ? A MET 645 
245 1 Y 1 A MET 646 ? A MET 646 
246 1 Y 1 A ASP 647 ? A ASP 647 
247 1 Y 1 A GLN 648 ? A GLN 648 
248 1 Y 1 A ASP 649 ? A ASP 649 
249 1 Y 1 A ASP 650 ? A ASP 650 
250 1 Y 1 A GLY 651 ? A GLY 651 
251 1 Y 1 A VAL 652 ? A VAL 652 
252 1 Y 1 A ARG 653 ? A ARG 653 
253 1 Y 1 A ASN 654 ? A ASN 654 
254 1 Y 1 A ARG 655 ? A ARG 655 
255 1 Y 1 A GLN 656 ? A GLN 656 
256 1 Y 1 A LYS 657 ? A LYS 657 
257 1 Y 1 A ASN 658 ? A ASN 658 
258 1 Y 1 A ARG 659 ? A ARG 659 
259 1 Y 1 A SER 660 ? A SER 660 
260 1 Y 1 A TRP 661 ? A TRP 661 
261 1 Y 1 A LYS 662 ? A LYS 662 
262 1 Y 1 A TYR 663 ? A TYR 663 
263 1 Y 1 A ASN 664 ? A ASN 664 
264 1 Y 1 A GLN 665 ? A GLN 665 
265 1 Y 1 A SER 666 ? A SER 666 
266 1 Y 1 A ILE 667 ? A ILE 667 
267 1 Y 1 A SER 668 ? A SER 668 
268 1 Y 1 A LEU 669 ? A LEU 669 
269 1 Y 1 A ARG 670 ? A ARG 670 
270 1 Y 1 A ARG 671 ? A ARG 671 
271 1 Y 1 A PRO 672 ? A PRO 672 
272 1 Y 1 A ARG 673 ? A ARG 673 
273 1 Y 1 A LEU 674 ? A LEU 674 
274 1 Y 1 A ALA 675 ? A ALA 675 
275 1 Y 1 A SER 676 ? A SER 676 
276 1 Y 1 A GLN 677 ? A GLN 677 
277 1 Y 1 A SER 678 ? A SER 678 
278 1 Y 1 A LYS 679 ? A LYS 679 
279 1 Y 1 A ALA 680 ? A ALA 680 
280 1 Y 1 A ARG 681 ? A ARG 681 
281 1 Y 1 A ASP 682 ? A ASP 682 
282 1 Y 1 A THR 683 ? A THR 683 
283 1 Y 1 A LYS 684 ? A LYS 684 
284 1 Y 1 A VAL 685 ? A VAL 685 
285 1 Y 1 A LEU 686 ? A LEU 686 
286 1 Y 1 A ILE 687 ? A ILE 687 
287 1 Y 1 A GLU 688 ? A GLU 688 
288 1 Y 1 A ASP 689 ? A ASP 689 
289 1 Y 1 A THR 690 ? A THR 690 
290 1 Y 1 A ASP 691 ? A ASP 691 
291 1 Y 1 A ASP 692 ? A ASP 692 
292 1 Y 1 A GLU 693 ? A GLU 693 
293 1 Y 1 A ALA 694 ? A ALA 694 
294 1 Y 1 A ASN 695 ? A ASN 695 
295 1 Y 1 A THR 696 ? A THR 696 
296 1 Y 1 A SER 697 ? A SER 697 
297 1 Y 1 A ARG 698 ? A ARG 698 
298 1 Y 1 A GLU 699 ? A GLU 699 
299 1 Y 1 A ASN 700 ? A ASN 700 
300 1 Y 1 A LEU 701 ? A LEU 701 
301 1 Y 1 A TYR 702 ? A TYR 702 
302 1 Y 1 A PHE 703 ? A PHE 703 
303 1 Y 1 A GLN 704 ? A GLN 704 
304 1 Y 1 B MET 1   ? B MET 1   
305 1 Y 1 B LYS 2   ? B LYS 2   
306 1 Y 1 B PHE 3   ? B PHE 3   
307 1 Y 1 B ALA 4   ? B ALA 4   
308 1 Y 1 B GLU 5   ? B GLU 5   
309 1 Y 1 B HIS 6   ? B HIS 6   
310 1 Y 1 B LEU 7   ? B LEU 7   
311 1 Y 1 B SER 8   ? B SER 8   
312 1 Y 1 B ALA 9   ? B ALA 9   
313 1 Y 1 B HIS 10  ? B HIS 10  
314 1 Y 1 B ILE 11  ? B ILE 11  
315 1 Y 1 B THR 12  ? B THR 12  
316 1 Y 1 B PRO 13  ? B PRO 13  
317 1 Y 1 B GLU 14  ? B GLU 14  
318 1 Y 1 B TRP 15  ? B TRP 15  
319 1 Y 1 B ARG 16  ? B ARG 16  
320 1 Y 1 B LYS 17  ? B LYS 17  
321 1 Y 1 B GLN 18  ? B GLN 18  
322 1 Y 1 B TYR 19  ? B TYR 19  
323 1 Y 1 B ILE 20  ? B ILE 20  
324 1 Y 1 B GLN 21  ? B GLN 21  
325 1 Y 1 B TYR 22  ? B TYR 22  
326 1 Y 1 B GLU 23  ? B GLU 23  
327 1 Y 1 B ALA 24  ? B ALA 24  
328 1 Y 1 B PHE 25  ? B PHE 25  
329 1 Y 1 B LYS 26  ? B LYS 26  
330 1 Y 1 B ASP 27  ? B ASP 27  
331 1 Y 1 B MET 28  ? B MET 28  
332 1 Y 1 B LEU 29  ? B LEU 29  
333 1 Y 1 B TYR 30  ? B TYR 30  
334 1 Y 1 B SER 31  ? B SER 31  
335 1 Y 1 B ALA 32  ? B ALA 32  
336 1 Y 1 B GLN 33  ? B GLN 33  
337 1 Y 1 B ASP 34  ? B ASP 34  
338 1 Y 1 B GLN 35  ? B GLN 35  
339 1 Y 1 B ALA 36  ? B ALA 36  
340 1 Y 1 B PRO 37  ? B PRO 37  
341 1 Y 1 B SER 38  ? B SER 38  
342 1 Y 1 B VAL 39  ? B VAL 39  
343 1 Y 1 B GLU 40  ? B GLU 40  
344 1 Y 1 B VAL 41  ? B VAL 41  
345 1 Y 1 B THR 42  ? B THR 42  
346 1 Y 1 B ASP 43  ? B ASP 43  
347 1 Y 1 B GLU 44  ? B GLU 44  
348 1 Y 1 B ASP 45  ? B ASP 45  
349 1 Y 1 B THR 46  ? B THR 46  
350 1 Y 1 B VAL 47  ? B VAL 47  
351 1 Y 1 B LYS 48  ? B LYS 48  
352 1 Y 1 B ARG 49  ? B ARG 49  
353 1 Y 1 B TYR 50  ? B TYR 50  
354 1 Y 1 B PHE 51  ? B PHE 51  
355 1 Y 1 B ALA 52  ? B ALA 52  
356 1 Y 1 B LYS 53  ? B LYS 53  
357 1 Y 1 B PHE 54  ? B PHE 54  
358 1 Y 1 B GLU 55  ? B GLU 55  
359 1 Y 1 B GLU 56  ? B GLU 56  
360 1 Y 1 B LYS 57  ? B LYS 57  
361 1 Y 1 B PHE 58  ? B PHE 58  
362 1 Y 1 B PHE 59  ? B PHE 59  
363 1 Y 1 B GLN 60  ? B GLN 60  
364 1 Y 1 B THR 61  ? B THR 61  
365 1 Y 1 B CYS 62  ? B CYS 62  
366 1 Y 1 B GLU 63  ? B GLU 63  
367 1 Y 1 B LYS 64  ? B LYS 64  
368 1 Y 1 B GLU 65  ? B GLU 65  
369 1 Y 1 B LEU 66  ? B LEU 66  
370 1 Y 1 B ALA 67  ? B ALA 67  
371 1 Y 1 B LYS 68  ? B LYS 68  
372 1 Y 1 B ILE 69  ? B ILE 69  
373 1 Y 1 B ASN 70  ? B ASN 70  
374 1 Y 1 B THR 71  ? B THR 71  
375 1 Y 1 B PHE 72  ? B PHE 72  
376 1 Y 1 B TYR 73  ? B TYR 73  
377 1 Y 1 B SER 74  ? B SER 74  
378 1 Y 1 B GLU 75  ? B GLU 75  
379 1 Y 1 B LYS 76  ? B LYS 76  
380 1 Y 1 B LEU 77  ? B LEU 77  
381 1 Y 1 B ALA 78  ? B ALA 78  
382 1 Y 1 B GLU 79  ? B GLU 79  
383 1 Y 1 B ALA 80  ? B ALA 80  
384 1 Y 1 B GLN 81  ? B GLN 81  
385 1 Y 1 B ARG 82  ? B ARG 82  
386 1 Y 1 B ARG 83  ? B ARG 83  
387 1 Y 1 B PHE 84  ? B PHE 84  
388 1 Y 1 B ALA 85  ? B ALA 85  
389 1 Y 1 B THR 86  ? B THR 86  
390 1 Y 1 B LEU 87  ? B LEU 87  
391 1 Y 1 B GLN 88  ? B GLN 88  
392 1 Y 1 B ASN 89  ? B ASN 89  
393 1 Y 1 B GLU 90  ? B GLU 90  
394 1 Y 1 B LEU 91  ? B LEU 91  
395 1 Y 1 B GLN 92  ? B GLN 92  
396 1 Y 1 B SER 93  ? B SER 93  
397 1 Y 1 B SER 94  ? B SER 94  
398 1 Y 1 B LEU 95  ? B LEU 95  
399 1 Y 1 B ASP 96  ? B ASP 96  
400 1 Y 1 B ALA 97  ? B ALA 97  
401 1 Y 1 B GLN 98  ? B GLN 98  
402 1 Y 1 B LYS 99  ? B LYS 99  
403 1 Y 1 B GLU 100 ? B GLU 100 
404 1 Y 1 B SER 101 ? B SER 101 
405 1 Y 1 B THR 102 ? B THR 102 
406 1 Y 1 B GLY 103 ? B GLY 103 
407 1 Y 1 B VAL 104 ? B VAL 104 
408 1 Y 1 B THR 105 ? B THR 105 
409 1 Y 1 B THR 106 ? B THR 106 
410 1 Y 1 B LEU 107 ? B LEU 107 
411 1 Y 1 B ARG 108 ? B ARG 108 
412 1 Y 1 B GLN 109 ? B GLN 109 
413 1 Y 1 B ARG 110 ? B ARG 110 
414 1 Y 1 B ARG 111 ? B ARG 111 
415 1 Y 1 B LYS 112 ? B LYS 112 
416 1 Y 1 B PRO 113 ? B PRO 113 
417 1 Y 1 B VAL 114 ? B VAL 114 
418 1 Y 1 B PHE 115 ? B PHE 115 
419 1 Y 1 B HIS 116 ? B HIS 116 
420 1 Y 1 B LEU 117 ? B LEU 117 
421 1 Y 1 B SER 118 ? B SER 118 
422 1 Y 1 B HIS 119 ? B HIS 119 
423 1 Y 1 B GLU 120 ? B GLU 120 
424 1 Y 1 B GLU 121 ? B GLU 121 
425 1 Y 1 B ARG 122 ? B ARG 122 
426 1 Y 1 B VAL 123 ? B VAL 123 
427 1 Y 1 B GLN 124 ? B GLN 124 
428 1 Y 1 B HIS 125 ? B HIS 125 
429 1 Y 1 B ARG 126 ? B ARG 126 
430 1 Y 1 B ASN 127 ? B ASN 127 
431 1 Y 1 B ILE 128 ? B ILE 128 
432 1 Y 1 B LYS 129 ? B LYS 129 
433 1 Y 1 B ASP 130 ? B ASP 130 
434 1 Y 1 B LEU 131 ? B LEU 131 
435 1 Y 1 B LYS 132 ? B LYS 132 
436 1 Y 1 B LEU 133 ? B LEU 133 
437 1 Y 1 B ALA 134 ? B ALA 134 
438 1 Y 1 B PHE 135 ? B PHE 135 
439 1 Y 1 B SER 136 ? B SER 136 
440 1 Y 1 B GLU 137 ? B GLU 137 
441 1 Y 1 B PHE 138 ? B PHE 138 
442 1 Y 1 B TYR 139 ? B TYR 139 
443 1 Y 1 B LEU 140 ? B LEU 140 
444 1 Y 1 B SER 141 ? B SER 141 
445 1 Y 1 B LEU 142 ? B LEU 142 
446 1 Y 1 B ILE 143 ? B ILE 143 
447 1 Y 1 B LEU 144 ? B LEU 144 
448 1 Y 1 B LEU 145 ? B LEU 145 
449 1 Y 1 B GLN 146 ? B GLN 146 
450 1 Y 1 B ASN 147 ? B ASN 147 
451 1 Y 1 B TYR 148 ? B TYR 148 
452 1 Y 1 B GLN 149 ? B GLN 149 
453 1 Y 1 B ASN 150 ? B ASN 150 
454 1 Y 1 B LEU 151 ? B LEU 151 
455 1 Y 1 B ASN 152 ? B ASN 152 
456 1 Y 1 B PHE 153 ? B PHE 153 
457 1 Y 1 B THR 154 ? B THR 154 
458 1 Y 1 B GLY 155 ? B GLY 155 
459 1 Y 1 B PHE 156 ? B PHE 156 
460 1 Y 1 B ARG 157 ? B ARG 157 
461 1 Y 1 B LYS 158 ? B LYS 158 
462 1 Y 1 B ILE 159 ? B ILE 159 
463 1 Y 1 B LEU 160 ? B LEU 160 
464 1 Y 1 B LYS 161 ? B LYS 161 
465 1 Y 1 B LYS 162 ? B LYS 162 
466 1 Y 1 B HIS 163 ? B HIS 163 
467 1 Y 1 B ASP 164 ? B ASP 164 
468 1 Y 1 B LYS 165 ? B LYS 165 
469 1 Y 1 B ILE 166 ? B ILE 166 
470 1 Y 1 B LEU 167 ? B LEU 167 
471 1 Y 1 B GLU 168 ? B GLU 168 
472 1 Y 1 B THR 169 ? B THR 169 
473 1 Y 1 B SER 170 ? B SER 170 
474 1 Y 1 B ARG 171 ? B ARG 171 
475 1 Y 1 B GLY 172 ? B GLY 172 
476 1 Y 1 B ALA 173 ? B ALA 173 
477 1 Y 1 B ASP 174 ? B ASP 174 
478 1 Y 1 B TRP 175 ? B TRP 175 
479 1 Y 1 B ARG 176 ? B ARG 176 
480 1 Y 1 B VAL 177 ? B VAL 177 
481 1 Y 1 B ALA 178 ? B ALA 178 
482 1 Y 1 B HIS 179 ? B HIS 179 
483 1 Y 1 B VAL 180 ? B VAL 180 
484 1 Y 1 B GLU 181 ? B GLU 181 
485 1 Y 1 B VAL 182 ? B VAL 182 
486 1 Y 1 B ALA 183 ? B ALA 183 
487 1 Y 1 B PRO 184 ? B PRO 184 
488 1 Y 1 B PHE 185 ? B PHE 185 
489 1 Y 1 B TYR 186 ? B TYR 186 
490 1 Y 1 B THR 187 ? B THR 187 
491 1 Y 1 B CYS 188 ? B CYS 188 
492 1 Y 1 B LYS 189 ? B LYS 189 
493 1 Y 1 B LYS 190 ? B LYS 190 
494 1 Y 1 B ILE 191 ? B ILE 191 
495 1 Y 1 B ASN 192 ? B ASN 192 
496 1 Y 1 B GLN 193 ? B GLN 193 
497 1 Y 1 B LEU 194 ? B LEU 194 
498 1 Y 1 B ILE 195 ? B ILE 195 
499 1 Y 1 B SER 196 ? B SER 196 
500 1 Y 1 B GLU 197 ? B GLU 197 
501 1 Y 1 B THR 198 ? B THR 198 
502 1 Y 1 B GLU 199 ? B GLU 199 
503 1 Y 1 B ALA 200 ? B ALA 200 
504 1 Y 1 B VAL 201 ? B VAL 201 
505 1 Y 1 B VAL 202 ? B VAL 202 
506 1 Y 1 B THR 203 ? B THR 203 
507 1 Y 1 B ASN 204 ? B ASN 204 
508 1 Y 1 B GLU 205 ? B GLU 205 
509 1 Y 1 B LEU 206 ? B LEU 206 
510 1 Y 1 B GLU 207 ? B GLU 207 
511 1 Y 1 B ASP 208 ? B ASP 208 
512 1 Y 1 B GLY 209 ? B GLY 209 
513 1 Y 1 B ASP 210 ? B ASP 210 
514 1 Y 1 B ARG 211 ? B ARG 211 
515 1 Y 1 B GLN 212 ? B GLN 212 
516 1 Y 1 B LYS 213 ? B LYS 213 
517 1 Y 1 B ALA 214 ? B ALA 214 
518 1 Y 1 B MET 215 ? B MET 215 
519 1 Y 1 B LYS 216 ? B LYS 216 
520 1 Y 1 B ARG 217 ? B ARG 217 
521 1 Y 1 B LEU 218 ? B LEU 218 
522 1 Y 1 B ARG 219 ? B ARG 219 
523 1 Y 1 B VAL 220 ? B VAL 220 
524 1 Y 1 B PRO 221 ? B PRO 221 
525 1 Y 1 B PRO 222 ? B PRO 222 
526 1 Y 1 B LEU 223 ? B LEU 223 
527 1 Y 1 B GLY 224 ? B GLY 224 
528 1 Y 1 B ALA 225 ? B ALA 225 
529 1 Y 1 B ARG 627 ? B ARG 627 
530 1 Y 1 B ASP 628 ? B ASP 628 
531 1 Y 1 B ILE 629 ? B ILE 629 
532 1 Y 1 B SER 630 ? B SER 630 
533 1 Y 1 B VAL 631 ? B VAL 631 
534 1 Y 1 B ALA 632 ? B ALA 632 
535 1 Y 1 B PRO 633 ? B PRO 633 
536 1 Y 1 B LEU 634 ? B LEU 634 
537 1 Y 1 B ASN 635 ? B ASN 635 
538 1 Y 1 B ALA 636 ? B ALA 636 
539 1 Y 1 B ASP 637 ? B ASP 637 
540 1 Y 1 B ASP 638 ? B ASP 638 
541 1 Y 1 B GLN 639 ? B GLN 639 
542 1 Y 1 B THR 640 ? B THR 640 
543 1 Y 1 B LEU 641 ? B LEU 641 
544 1 Y 1 B LEU 642 ? B LEU 642 
545 1 Y 1 B GLU 643 ? B GLU 643 
546 1 Y 1 B GLN 644 ? B GLN 644 
547 1 Y 1 B MET 645 ? B MET 645 
548 1 Y 1 B MET 646 ? B MET 646 
549 1 Y 1 B ASP 647 ? B ASP 647 
550 1 Y 1 B GLN 648 ? B GLN 648 
551 1 Y 1 B ASP 649 ? B ASP 649 
552 1 Y 1 B ASP 650 ? B ASP 650 
553 1 Y 1 B GLY 651 ? B GLY 651 
554 1 Y 1 B VAL 652 ? B VAL 652 
555 1 Y 1 B ARG 653 ? B ARG 653 
556 1 Y 1 B ASN 654 ? B ASN 654 
557 1 Y 1 B ARG 655 ? B ARG 655 
558 1 Y 1 B GLN 656 ? B GLN 656 
559 1 Y 1 B LYS 657 ? B LYS 657 
560 1 Y 1 B ASN 658 ? B ASN 658 
561 1 Y 1 B ARG 659 ? B ARG 659 
562 1 Y 1 B SER 660 ? B SER 660 
563 1 Y 1 B TRP 661 ? B TRP 661 
564 1 Y 1 B LYS 662 ? B LYS 662 
565 1 Y 1 B TYR 663 ? B TYR 663 
566 1 Y 1 B ASN 664 ? B ASN 664 
567 1 Y 1 B GLN 665 ? B GLN 665 
568 1 Y 1 B SER 666 ? B SER 666 
569 1 Y 1 B ILE 667 ? B ILE 667 
570 1 Y 1 B SER 668 ? B SER 668 
571 1 Y 1 B LEU 669 ? B LEU 669 
572 1 Y 1 B ARG 670 ? B ARG 670 
573 1 Y 1 B ARG 671 ? B ARG 671 
574 1 Y 1 B PRO 672 ? B PRO 672 
575 1 Y 1 B ARG 673 ? B ARG 673 
576 1 Y 1 B LEU 674 ? B LEU 674 
577 1 Y 1 B ALA 675 ? B ALA 675 
578 1 Y 1 B SER 676 ? B SER 676 
579 1 Y 1 B GLN 677 ? B GLN 677 
580 1 Y 1 B SER 678 ? B SER 678 
581 1 Y 1 B LYS 679 ? B LYS 679 
582 1 Y 1 B ALA 680 ? B ALA 680 
583 1 Y 1 B ARG 681 ? B ARG 681 
584 1 Y 1 B ASP 682 ? B ASP 682 
585 1 Y 1 B THR 683 ? B THR 683 
586 1 Y 1 B LYS 684 ? B LYS 684 
587 1 Y 1 B VAL 685 ? B VAL 685 
588 1 Y 1 B LEU 686 ? B LEU 686 
589 1 Y 1 B ILE 687 ? B ILE 687 
590 1 Y 1 B GLU 688 ? B GLU 688 
591 1 Y 1 B ASP 689 ? B ASP 689 
592 1 Y 1 B THR 690 ? B THR 690 
593 1 Y 1 B ASP 691 ? B ASP 691 
594 1 Y 1 B ASP 692 ? B ASP 692 
595 1 Y 1 B GLU 693 ? B GLU 693 
596 1 Y 1 B ALA 694 ? B ALA 694 
597 1 Y 1 B ASN 695 ? B ASN 695 
598 1 Y 1 B THR 696 ? B THR 696 
599 1 Y 1 B SER 697 ? B SER 697 
600 1 Y 1 B ARG 698 ? B ARG 698 
601 1 Y 1 B GLU 699 ? B GLU 699 
602 1 Y 1 B ASN 700 ? B ASN 700 
603 1 Y 1 B LEU 701 ? B LEU 701 
604 1 Y 1 B TYR 702 ? B TYR 702 
605 1 Y 1 B PHE 703 ? B PHE 703 
606 1 Y 1 B GLN 704 ? B GLN 704 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
3PE P    P N N 1   
3PE N    N N N 2   
3PE O11  O N N 3   
3PE O12  O N N 4   
3PE O13  O N N 5   
3PE O14  O N N 6   
3PE C11  C N N 7   
3PE C12  C N N 8   
3PE C1   C N N 9   
3PE C2   C N R 10  
3PE C3   C N N 11  
3PE O31  O N N 12  
3PE O32  O N N 13  
3PE C31  C N N 14  
3PE C32  C N N 15  
3PE C33  C N N 16  
3PE C34  C N N 17  
3PE C35  C N N 18  
3PE C36  C N N 19  
3PE C37  C N N 20  
3PE C38  C N N 21  
3PE C39  C N N 22  
3PE C3A  C N N 23  
3PE C3B  C N N 24  
3PE C3C  C N N 25  
3PE C3D  C N N 26  
3PE C3E  C N N 27  
3PE C3F  C N N 28  
3PE C3G  C N N 29  
3PE C3H  C N N 30  
3PE C3I  C N N 31  
3PE O21  O N N 32  
3PE O22  O N N 33  
3PE C21  C N N 34  
3PE C22  C N N 35  
3PE C23  C N N 36  
3PE C24  C N N 37  
3PE C25  C N N 38  
3PE C26  C N N 39  
3PE C27  C N N 40  
3PE C28  C N N 41  
3PE C29  C N N 42  
3PE C2A  C N N 43  
3PE C2B  C N N 44  
3PE C2C  C N N 45  
3PE C2D  C N N 46  
3PE C2E  C N N 47  
3PE C2F  C N N 48  
3PE C2G  C N N 49  
3PE C2H  C N N 50  
3PE C2I  C N N 51  
3PE HN1  H N N 52  
3PE HN2  H N N 53  
3PE H111 H N N 54  
3PE H112 H N N 55  
3PE H121 H N N 56  
3PE H122 H N N 57  
3PE H11  H N N 58  
3PE H12  H N N 59  
3PE H2   H N N 60  
3PE H31  H N N 61  
3PE H32  H N N 62  
3PE H321 H N N 63  
3PE H322 H N N 64  
3PE H331 H N N 65  
3PE H332 H N N 66  
3PE H341 H N N 67  
3PE H342 H N N 68  
3PE H351 H N N 69  
3PE H352 H N N 70  
3PE H361 H N N 71  
3PE H362 H N N 72  
3PE H371 H N N 73  
3PE H372 H N N 74  
3PE H381 H N N 75  
3PE H382 H N N 76  
3PE H391 H N N 77  
3PE H392 H N N 78  
3PE H3A1 H N N 79  
3PE H3A2 H N N 80  
3PE H3B1 H N N 81  
3PE H3B2 H N N 82  
3PE H3C1 H N N 83  
3PE H3C2 H N N 84  
3PE H3D1 H N N 85  
3PE H3D2 H N N 86  
3PE H3E1 H N N 87  
3PE H3E2 H N N 88  
3PE H3F1 H N N 89  
3PE H3F2 H N N 90  
3PE H3G1 H N N 91  
3PE H3G2 H N N 92  
3PE H3H1 H N N 93  
3PE H3H2 H N N 94  
3PE H3I1 H N N 95  
3PE H3I2 H N N 96  
3PE H3I3 H N N 97  
3PE H221 H N N 98  
3PE H222 H N N 99  
3PE H231 H N N 100 
3PE H232 H N N 101 
3PE H241 H N N 102 
3PE H242 H N N 103 
3PE H251 H N N 104 
3PE H252 H N N 105 
3PE H261 H N N 106 
3PE H262 H N N 107 
3PE H271 H N N 108 
3PE H272 H N N 109 
3PE H281 H N N 110 
3PE H282 H N N 111 
3PE H291 H N N 112 
3PE H292 H N N 113 
3PE H2A1 H N N 114 
3PE H2A2 H N N 115 
3PE H2B1 H N N 116 
3PE H2B2 H N N 117 
3PE H2C1 H N N 118 
3PE H2C2 H N N 119 
3PE H2D1 H N N 120 
3PE H2D2 H N N 121 
3PE H2E1 H N N 122 
3PE H2E2 H N N 123 
3PE H2F1 H N N 124 
3PE H2F2 H N N 125 
3PE H2G1 H N N 126 
3PE H2G2 H N N 127 
3PE H2H1 H N N 128 
3PE H2H2 H N N 129 
3PE H2I1 H N N 130 
3PE H2I2 H N N 131 
3PE H2I3 H N N 132 
3PE H1   H N N 133 
ACD C1   C N N 134 
ACD C2   C N N 135 
ACD C3   C N N 136 
ACD C4   C N N 137 
ACD C5   C N N 138 
ACD C6   C N N 139 
ACD C7   C N N 140 
ACD C8   C N N 141 
ACD C9   C N N 142 
ACD C10  C N N 143 
ACD C11  C N N 144 
ACD C12  C N N 145 
ACD C13  C N N 146 
ACD C14  C N N 147 
ACD C15  C N N 148 
ACD C16  C N N 149 
ACD C17  C N N 150 
ACD C18  C N N 151 
ACD C19  C N N 152 
ACD C20  C N N 153 
ACD O1   O N N 154 
ACD O2   O N N 155 
ACD H21  H N N 156 
ACD H22  H N N 157 
ACD H31  H N N 158 
ACD H32  H N N 159 
ACD H41  H N N 160 
ACD H42  H N N 161 
ACD H5   H N N 162 
ACD H6   H N N 163 
ACD H71  H N N 164 
ACD H72  H N N 165 
ACD H8   H N N 166 
ACD H9   H N N 167 
ACD H101 H N N 168 
ACD H102 H N N 169 
ACD H11  H N N 170 
ACD H12  H N N 171 
ACD H131 H N N 172 
ACD H132 H N N 173 
ACD H14  H N N 174 
ACD H15  H N N 175 
ACD H161 H N N 176 
ACD H162 H N N 177 
ACD H171 H N N 178 
ACD H172 H N N 179 
ACD H181 H N N 180 
ACD H182 H N N 181 
ACD H191 H N N 182 
ACD H192 H N N 183 
ACD H201 H N N 184 
ACD H202 H N N 185 
ACD H203 H N N 186 
ACD HO2  H N N 187 
ALA N    N N N 188 
ALA CA   C N S 189 
ALA C    C N N 190 
ALA O    O N N 191 
ALA CB   C N N 192 
ALA OXT  O N N 193 
ALA H    H N N 194 
ALA H2   H N N 195 
ALA HA   H N N 196 
ALA HB1  H N N 197 
ALA HB2  H N N 198 
ALA HB3  H N N 199 
ALA HXT  H N N 200 
ARG N    N N N 201 
ARG CA   C N S 202 
ARG C    C N N 203 
ARG O    O N N 204 
ARG CB   C N N 205 
ARG CG   C N N 206 
ARG CD   C N N 207 
ARG NE   N N N 208 
ARG CZ   C N N 209 
ARG NH1  N N N 210 
ARG NH2  N N N 211 
ARG OXT  O N N 212 
ARG H    H N N 213 
ARG H2   H N N 214 
ARG HA   H N N 215 
ARG HB2  H N N 216 
ARG HB3  H N N 217 
ARG HG2  H N N 218 
ARG HG3  H N N 219 
ARG HD2  H N N 220 
ARG HD3  H N N 221 
ARG HE   H N N 222 
ARG HH11 H N N 223 
ARG HH12 H N N 224 
ARG HH21 H N N 225 
ARG HH22 H N N 226 
ARG HXT  H N N 227 
ASN N    N N N 228 
ASN CA   C N S 229 
ASN C    C N N 230 
ASN O    O N N 231 
ASN CB   C N N 232 
ASN CG   C N N 233 
ASN OD1  O N N 234 
ASN ND2  N N N 235 
ASN OXT  O N N 236 
ASN H    H N N 237 
ASN H2   H N N 238 
ASN HA   H N N 239 
ASN HB2  H N N 240 
ASN HB3  H N N 241 
ASN HD21 H N N 242 
ASN HD22 H N N 243 
ASN HXT  H N N 244 
ASP N    N N N 245 
ASP CA   C N S 246 
ASP C    C N N 247 
ASP O    O N N 248 
ASP CB   C N N 249 
ASP CG   C N N 250 
ASP OD1  O N N 251 
ASP OD2  O N N 252 
ASP OXT  O N N 253 
ASP H    H N N 254 
ASP H2   H N N 255 
ASP HA   H N N 256 
ASP HB2  H N N 257 
ASP HB3  H N N 258 
ASP HD2  H N N 259 
ASP HXT  H N N 260 
CLR C1   C N N 261 
CLR C2   C N N 262 
CLR C3   C N S 263 
CLR C4   C N N 264 
CLR C5   C N N 265 
CLR C6   C N N 266 
CLR C7   C N N 267 
CLR C8   C N S 268 
CLR C9   C N S 269 
CLR C10  C N R 270 
CLR C11  C N N 271 
CLR C12  C N N 272 
CLR C13  C N R 273 
CLR C14  C N S 274 
CLR C15  C N N 275 
CLR C16  C N N 276 
CLR C17  C N R 277 
CLR C18  C N N 278 
CLR C19  C N N 279 
CLR C20  C N R 280 
CLR C21  C N N 281 
CLR C22  C N N 282 
CLR C23  C N N 283 
CLR C24  C N N 284 
CLR C25  C N N 285 
CLR C26  C N N 286 
CLR C27  C N N 287 
CLR O1   O N N 288 
CLR H11  H N N 289 
CLR H12  H N N 290 
CLR H21  H N N 291 
CLR H22  H N N 292 
CLR H3   H N N 293 
CLR H41  H N N 294 
CLR H42  H N N 295 
CLR H6   H N N 296 
CLR H71  H N N 297 
CLR H72  H N N 298 
CLR H8   H N N 299 
CLR H9   H N N 300 
CLR H111 H N N 301 
CLR H112 H N N 302 
CLR H121 H N N 303 
CLR H122 H N N 304 
CLR H14  H N N 305 
CLR H151 H N N 306 
CLR H152 H N N 307 
CLR H161 H N N 308 
CLR H162 H N N 309 
CLR H17  H N N 310 
CLR H181 H N N 311 
CLR H182 H N N 312 
CLR H183 H N N 313 
CLR H191 H N N 314 
CLR H192 H N N 315 
CLR H193 H N N 316 
CLR H20  H N N 317 
CLR H211 H N N 318 
CLR H212 H N N 319 
CLR H213 H N N 320 
CLR H221 H N N 321 
CLR H222 H N N 322 
CLR H231 H N N 323 
CLR H232 H N N 324 
CLR H241 H N N 325 
CLR H242 H N N 326 
CLR H25  H N N 327 
CLR H261 H N N 328 
CLR H262 H N N 329 
CLR H263 H N N 330 
CLR H271 H N N 331 
CLR H272 H N N 332 
CLR H273 H N N 333 
CLR H1   H N N 334 
CYS N    N N N 335 
CYS CA   C N R 336 
CYS C    C N N 337 
CYS O    O N N 338 
CYS CB   C N N 339 
CYS SG   S N N 340 
CYS OXT  O N N 341 
CYS H    H N N 342 
CYS H2   H N N 343 
CYS HA   H N N 344 
CYS HB2  H N N 345 
CYS HB3  H N N 346 
CYS HG   H N N 347 
CYS HXT  H N N 348 
GLN N    N N N 349 
GLN CA   C N S 350 
GLN C    C N N 351 
GLN O    O N N 352 
GLN CB   C N N 353 
GLN CG   C N N 354 
GLN CD   C N N 355 
GLN OE1  O N N 356 
GLN NE2  N N N 357 
GLN OXT  O N N 358 
GLN H    H N N 359 
GLN H2   H N N 360 
GLN HA   H N N 361 
GLN HB2  H N N 362 
GLN HB3  H N N 363 
GLN HG2  H N N 364 
GLN HG3  H N N 365 
GLN HE21 H N N 366 
GLN HE22 H N N 367 
GLN HXT  H N N 368 
GLU N    N N N 369 
GLU CA   C N S 370 
GLU C    C N N 371 
GLU O    O N N 372 
GLU CB   C N N 373 
GLU CG   C N N 374 
GLU CD   C N N 375 
GLU OE1  O N N 376 
GLU OE2  O N N 377 
GLU OXT  O N N 378 
GLU H    H N N 379 
GLU H2   H N N 380 
GLU HA   H N N 381 
GLU HB2  H N N 382 
GLU HB3  H N N 383 
GLU HG2  H N N 384 
GLU HG3  H N N 385 
GLU HE2  H N N 386 
GLU HXT  H N N 387 
GLY N    N N N 388 
GLY CA   C N N 389 
GLY C    C N N 390 
GLY O    O N N 391 
GLY OXT  O N N 392 
GLY H    H N N 393 
GLY H2   H N N 394 
GLY HA2  H N N 395 
GLY HA3  H N N 396 
GLY HXT  H N N 397 
HIS N    N N N 398 
HIS CA   C N S 399 
HIS C    C N N 400 
HIS O    O N N 401 
HIS CB   C N N 402 
HIS CG   C Y N 403 
HIS ND1  N Y N 404 
HIS CD2  C Y N 405 
HIS CE1  C Y N 406 
HIS NE2  N Y N 407 
HIS OXT  O N N 408 
HIS H    H N N 409 
HIS H2   H N N 410 
HIS HA   H N N 411 
HIS HB2  H N N 412 
HIS HB3  H N N 413 
HIS HD1  H N N 414 
HIS HD2  H N N 415 
HIS HE1  H N N 416 
HIS HE2  H N N 417 
HIS HXT  H N N 418 
HOH O    O N N 419 
HOH H1   H N N 420 
HOH H2   H N N 421 
ILE N    N N N 422 
ILE CA   C N S 423 
ILE C    C N N 424 
ILE O    O N N 425 
ILE CB   C N S 426 
ILE CG1  C N N 427 
ILE CG2  C N N 428 
ILE CD1  C N N 429 
ILE OXT  O N N 430 
ILE H    H N N 431 
ILE H2   H N N 432 
ILE HA   H N N 433 
ILE HB   H N N 434 
ILE HG12 H N N 435 
ILE HG13 H N N 436 
ILE HG21 H N N 437 
ILE HG22 H N N 438 
ILE HG23 H N N 439 
ILE HD11 H N N 440 
ILE HD12 H N N 441 
ILE HD13 H N N 442 
ILE HXT  H N N 443 
LEU N    N N N 444 
LEU CA   C N S 445 
LEU C    C N N 446 
LEU O    O N N 447 
LEU CB   C N N 448 
LEU CG   C N N 449 
LEU CD1  C N N 450 
LEU CD2  C N N 451 
LEU OXT  O N N 452 
LEU H    H N N 453 
LEU H2   H N N 454 
LEU HA   H N N 455 
LEU HB2  H N N 456 
LEU HB3  H N N 457 
LEU HG   H N N 458 
LEU HD11 H N N 459 
LEU HD12 H N N 460 
LEU HD13 H N N 461 
LEU HD21 H N N 462 
LEU HD22 H N N 463 
LEU HD23 H N N 464 
LEU HXT  H N N 465 
LYS N    N N N 466 
LYS CA   C N S 467 
LYS C    C N N 468 
LYS O    O N N 469 
LYS CB   C N N 470 
LYS CG   C N N 471 
LYS CD   C N N 472 
LYS CE   C N N 473 
LYS NZ   N N N 474 
LYS OXT  O N N 475 
LYS H    H N N 476 
LYS H2   H N N 477 
LYS HA   H N N 478 
LYS HB2  H N N 479 
LYS HB3  H N N 480 
LYS HG2  H N N 481 
LYS HG3  H N N 482 
LYS HD2  H N N 483 
LYS HD3  H N N 484 
LYS HE2  H N N 485 
LYS HE3  H N N 486 
LYS HZ1  H N N 487 
LYS HZ2  H N N 488 
LYS HZ3  H N N 489 
LYS HXT  H N N 490 
MET N    N N N 491 
MET CA   C N S 492 
MET C    C N N 493 
MET O    O N N 494 
MET CB   C N N 495 
MET CG   C N N 496 
MET SD   S N N 497 
MET CE   C N N 498 
MET OXT  O N N 499 
MET H    H N N 500 
MET H2   H N N 501 
MET HA   H N N 502 
MET HB2  H N N 503 
MET HB3  H N N 504 
MET HG2  H N N 505 
MET HG3  H N N 506 
MET HE1  H N N 507 
MET HE2  H N N 508 
MET HE3  H N N 509 
MET HXT  H N N 510 
PHE N    N N N 511 
PHE CA   C N S 512 
PHE C    C N N 513 
PHE O    O N N 514 
PHE CB   C N N 515 
PHE CG   C Y N 516 
PHE CD1  C Y N 517 
PHE CD2  C Y N 518 
PHE CE1  C Y N 519 
PHE CE2  C Y N 520 
PHE CZ   C Y N 521 
PHE OXT  O N N 522 
PHE H    H N N 523 
PHE H2   H N N 524 
PHE HA   H N N 525 
PHE HB2  H N N 526 
PHE HB3  H N N 527 
PHE HD1  H N N 528 
PHE HD2  H N N 529 
PHE HE1  H N N 530 
PHE HE2  H N N 531 
PHE HZ   H N N 532 
PHE HXT  H N N 533 
PLM C1   C N N 534 
PLM O1   O N N 535 
PLM O2   O N N 536 
PLM C2   C N N 537 
PLM C3   C N N 538 
PLM C4   C N N 539 
PLM C5   C N N 540 
PLM C6   C N N 541 
PLM C7   C N N 542 
PLM C8   C N N 543 
PLM C9   C N N 544 
PLM CA   C N N 545 
PLM CB   C N N 546 
PLM CC   C N N 547 
PLM CD   C N N 548 
PLM CE   C N N 549 
PLM CF   C N N 550 
PLM CG   C N N 551 
PLM H    H N N 552 
PLM H21  H N N 553 
PLM H22  H N N 554 
PLM H31  H N N 555 
PLM H32  H N N 556 
PLM H41  H N N 557 
PLM H42  H N N 558 
PLM H51  H N N 559 
PLM H52  H N N 560 
PLM H61  H N N 561 
PLM H62  H N N 562 
PLM H71  H N N 563 
PLM H72  H N N 564 
PLM H81  H N N 565 
PLM H82  H N N 566 
PLM H91  H N N 567 
PLM H92  H N N 568 
PLM HA1  H N N 569 
PLM HA2  H N N 570 
PLM HB1  H N N 571 
PLM HB2  H N N 572 
PLM HC1  H N N 573 
PLM HC2  H N N 574 
PLM HD1  H N N 575 
PLM HD2  H N N 576 
PLM HE1  H N N 577 
PLM HE2  H N N 578 
PLM HF1  H N N 579 
PLM HF2  H N N 580 
PLM HG1  H N N 581 
PLM HG2  H N N 582 
PLM HG3  H N N 583 
PRO N    N N N 584 
PRO CA   C N S 585 
PRO C    C N N 586 
PRO O    O N N 587 
PRO CB   C N N 588 
PRO CG   C N N 589 
PRO CD   C N N 590 
PRO OXT  O N N 591 
PRO H    H N N 592 
PRO HA   H N N 593 
PRO HB2  H N N 594 
PRO HB3  H N N 595 
PRO HG2  H N N 596 
PRO HG3  H N N 597 
PRO HD2  H N N 598 
PRO HD3  H N N 599 
PRO HXT  H N N 600 
SER N    N N N 601 
SER CA   C N S 602 
SER C    C N N 603 
SER O    O N N 604 
SER CB   C N N 605 
SER OG   O N N 606 
SER OXT  O N N 607 
SER H    H N N 608 
SER H2   H N N 609 
SER HA   H N N 610 
SER HB2  H N N 611 
SER HB3  H N N 612 
SER HG   H N N 613 
SER HXT  H N N 614 
THR N    N N N 615 
THR CA   C N S 616 
THR C    C N N 617 
THR O    O N N 618 
THR CB   C N R 619 
THR OG1  O N N 620 
THR CG2  C N N 621 
THR OXT  O N N 622 
THR H    H N N 623 
THR H2   H N N 624 
THR HA   H N N 625 
THR HB   H N N 626 
THR HG1  H N N 627 
THR HG21 H N N 628 
THR HG22 H N N 629 
THR HG23 H N N 630 
THR HXT  H N N 631 
TRP N    N N N 632 
TRP CA   C N S 633 
TRP C    C N N 634 
TRP O    O N N 635 
TRP CB   C N N 636 
TRP CG   C Y N 637 
TRP CD1  C Y N 638 
TRP CD2  C Y N 639 
TRP NE1  N Y N 640 
TRP CE2  C Y N 641 
TRP CE3  C Y N 642 
TRP CZ2  C Y N 643 
TRP CZ3  C Y N 644 
TRP CH2  C Y N 645 
TRP OXT  O N N 646 
TRP H    H N N 647 
TRP H2   H N N 648 
TRP HA   H N N 649 
TRP HB2  H N N 650 
TRP HB3  H N N 651 
TRP HD1  H N N 652 
TRP HE1  H N N 653 
TRP HE3  H N N 654 
TRP HZ2  H N N 655 
TRP HZ3  H N N 656 
TRP HH2  H N N 657 
TRP HXT  H N N 658 
TYR N    N N N 659 
TYR CA   C N S 660 
TYR C    C N N 661 
TYR O    O N N 662 
TYR CB   C N N 663 
TYR CG   C Y N 664 
TYR CD1  C Y N 665 
TYR CD2  C Y N 666 
TYR CE1  C Y N 667 
TYR CE2  C Y N 668 
TYR CZ   C Y N 669 
TYR OH   O N N 670 
TYR OXT  O N N 671 
TYR H    H N N 672 
TYR H2   H N N 673 
TYR HA   H N N 674 
TYR HB2  H N N 675 
TYR HB3  H N N 676 
TYR HD1  H N N 677 
TYR HD2  H N N 678 
TYR HE1  H N N 679 
TYR HE2  H N N 680 
TYR HH   H N N 681 
TYR HXT  H N N 682 
VAL N    N N N 683 
VAL CA   C N S 684 
VAL C    C N N 685 
VAL O    O N N 686 
VAL CB   C N N 687 
VAL CG1  C N N 688 
VAL CG2  C N N 689 
VAL OXT  O N N 690 
VAL H    H N N 691 
VAL H2   H N N 692 
VAL HA   H N N 693 
VAL HB   H N N 694 
VAL HG11 H N N 695 
VAL HG12 H N N 696 
VAL HG13 H N N 697 
VAL HG21 H N N 698 
VAL HG22 H N N 699 
VAL HG23 H N N 700 
VAL HXT  H N N 701 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
3PE P   O11  sing N N 1   
3PE P   O12  sing N N 2   
3PE P   O13  sing N N 3   
3PE P   O14  doub N N 4   
3PE N   C12  sing N N 5   
3PE N   HN1  sing N N 6   
3PE N   HN2  sing N N 7   
3PE O11 C1   sing N N 8   
3PE O13 C11  sing N N 9   
3PE C11 C12  sing N N 10  
3PE C11 H111 sing N N 11  
3PE C11 H112 sing N N 12  
3PE C12 H121 sing N N 13  
3PE C12 H122 sing N N 14  
3PE C1  C2   sing N N 15  
3PE C1  H11  sing N N 16  
3PE C1  H12  sing N N 17  
3PE C2  C3   sing N N 18  
3PE C2  O21  sing N N 19  
3PE C2  H2   sing N N 20  
3PE C3  O31  sing N N 21  
3PE C3  H31  sing N N 22  
3PE C3  H32  sing N N 23  
3PE O31 C31  sing N N 24  
3PE O32 C31  doub N N 25  
3PE C31 C32  sing N N 26  
3PE C32 C33  sing N N 27  
3PE C32 H321 sing N N 28  
3PE C32 H322 sing N N 29  
3PE C33 C34  sing N N 30  
3PE C33 H331 sing N N 31  
3PE C33 H332 sing N N 32  
3PE C34 C35  sing N N 33  
3PE C34 H341 sing N N 34  
3PE C34 H342 sing N N 35  
3PE C35 C36  sing N N 36  
3PE C35 H351 sing N N 37  
3PE C35 H352 sing N N 38  
3PE C36 C37  sing N N 39  
3PE C36 H361 sing N N 40  
3PE C36 H362 sing N N 41  
3PE C37 C38  sing N N 42  
3PE C37 H371 sing N N 43  
3PE C37 H372 sing N N 44  
3PE C38 C39  sing N N 45  
3PE C38 H381 sing N N 46  
3PE C38 H382 sing N N 47  
3PE C39 C3A  sing N N 48  
3PE C39 H391 sing N N 49  
3PE C39 H392 sing N N 50  
3PE C3A C3B  sing N N 51  
3PE C3A H3A1 sing N N 52  
3PE C3A H3A2 sing N N 53  
3PE C3B C3C  sing N N 54  
3PE C3B H3B1 sing N N 55  
3PE C3B H3B2 sing N N 56  
3PE C3C C3D  sing N N 57  
3PE C3C H3C1 sing N N 58  
3PE C3C H3C2 sing N N 59  
3PE C3D C3E  sing N N 60  
3PE C3D H3D1 sing N N 61  
3PE C3D H3D2 sing N N 62  
3PE C3E C3F  sing N N 63  
3PE C3E H3E1 sing N N 64  
3PE C3E H3E2 sing N N 65  
3PE C3F C3G  sing N N 66  
3PE C3F H3F1 sing N N 67  
3PE C3F H3F2 sing N N 68  
3PE C3G C3H  sing N N 69  
3PE C3G H3G1 sing N N 70  
3PE C3G H3G2 sing N N 71  
3PE C3H C3I  sing N N 72  
3PE C3H H3H1 sing N N 73  
3PE C3H H3H2 sing N N 74  
3PE C3I H3I1 sing N N 75  
3PE C3I H3I2 sing N N 76  
3PE C3I H3I3 sing N N 77  
3PE O21 C21  sing N N 78  
3PE O22 C21  doub N N 79  
3PE C21 C22  sing N N 80  
3PE C22 C23  sing N N 81  
3PE C22 H221 sing N N 82  
3PE C22 H222 sing N N 83  
3PE C23 C24  sing N N 84  
3PE C23 H231 sing N N 85  
3PE C23 H232 sing N N 86  
3PE C24 C25  sing N N 87  
3PE C24 H241 sing N N 88  
3PE C24 H242 sing N N 89  
3PE C25 C26  sing N N 90  
3PE C25 H251 sing N N 91  
3PE C25 H252 sing N N 92  
3PE C26 C27  sing N N 93  
3PE C26 H261 sing N N 94  
3PE C26 H262 sing N N 95  
3PE C27 C28  sing N N 96  
3PE C27 H271 sing N N 97  
3PE C27 H272 sing N N 98  
3PE C28 C29  sing N N 99  
3PE C28 H281 sing N N 100 
3PE C28 H282 sing N N 101 
3PE C29 C2A  sing N N 102 
3PE C29 H291 sing N N 103 
3PE C29 H292 sing N N 104 
3PE C2A C2B  sing N N 105 
3PE C2A H2A1 sing N N 106 
3PE C2A H2A2 sing N N 107 
3PE C2B C2C  sing N N 108 
3PE C2B H2B1 sing N N 109 
3PE C2B H2B2 sing N N 110 
3PE C2C C2D  sing N N 111 
3PE C2C H2C1 sing N N 112 
3PE C2C H2C2 sing N N 113 
3PE C2D C2E  sing N N 114 
3PE C2D H2D1 sing N N 115 
3PE C2D H2D2 sing N N 116 
3PE C2E C2F  sing N N 117 
3PE C2E H2E1 sing N N 118 
3PE C2E H2E2 sing N N 119 
3PE C2F C2G  sing N N 120 
3PE C2F H2F1 sing N N 121 
3PE C2F H2F2 sing N N 122 
3PE C2G C2H  sing N N 123 
3PE C2G H2G1 sing N N 124 
3PE C2G H2G2 sing N N 125 
3PE C2H C2I  sing N N 126 
3PE C2H H2H1 sing N N 127 
3PE C2H H2H2 sing N N 128 
3PE C2I H2I1 sing N N 129 
3PE C2I H2I2 sing N N 130 
3PE C2I H2I3 sing N N 131 
3PE O12 H1   sing N N 132 
ACD C1  C2   sing N N 133 
ACD C1  O1   doub N N 134 
ACD C1  O2   sing N N 135 
ACD C2  C3   sing N N 136 
ACD C2  H21  sing N N 137 
ACD C2  H22  sing N N 138 
ACD C3  C4   sing N N 139 
ACD C3  H31  sing N N 140 
ACD C3  H32  sing N N 141 
ACD C4  C5   sing N N 142 
ACD C4  H41  sing N N 143 
ACD C4  H42  sing N N 144 
ACD C5  C6   doub N Z 145 
ACD C5  H5   sing N N 146 
ACD C6  C7   sing N N 147 
ACD C6  H6   sing N N 148 
ACD C7  C8   sing N N 149 
ACD C7  H71  sing N N 150 
ACD C7  H72  sing N N 151 
ACD C8  C9   doub N Z 152 
ACD C8  H8   sing N N 153 
ACD C9  C10  sing N N 154 
ACD C9  H9   sing N N 155 
ACD C10 C11  sing N N 156 
ACD C10 H101 sing N N 157 
ACD C10 H102 sing N N 158 
ACD C11 C12  doub N Z 159 
ACD C11 H11  sing N N 160 
ACD C12 C13  sing N N 161 
ACD C12 H12  sing N N 162 
ACD C13 C14  sing N N 163 
ACD C13 H131 sing N N 164 
ACD C13 H132 sing N N 165 
ACD C14 C15  doub N Z 166 
ACD C14 H14  sing N N 167 
ACD C15 C16  sing N N 168 
ACD C15 H15  sing N N 169 
ACD C16 C17  sing N N 170 
ACD C16 H161 sing N N 171 
ACD C16 H162 sing N N 172 
ACD C17 C18  sing N N 173 
ACD C17 H171 sing N N 174 
ACD C17 H172 sing N N 175 
ACD C18 C19  sing N N 176 
ACD C18 H181 sing N N 177 
ACD C18 H182 sing N N 178 
ACD C19 C20  sing N N 179 
ACD C19 H191 sing N N 180 
ACD C19 H192 sing N N 181 
ACD C20 H201 sing N N 182 
ACD C20 H202 sing N N 183 
ACD C20 H203 sing N N 184 
ACD O2  HO2  sing N N 185 
ALA N   CA   sing N N 186 
ALA N   H    sing N N 187 
ALA N   H2   sing N N 188 
ALA CA  C    sing N N 189 
ALA CA  CB   sing N N 190 
ALA CA  HA   sing N N 191 
ALA C   O    doub N N 192 
ALA C   OXT  sing N N 193 
ALA CB  HB1  sing N N 194 
ALA CB  HB2  sing N N 195 
ALA CB  HB3  sing N N 196 
ALA OXT HXT  sing N N 197 
ARG N   CA   sing N N 198 
ARG N   H    sing N N 199 
ARG N   H2   sing N N 200 
ARG CA  C    sing N N 201 
ARG CA  CB   sing N N 202 
ARG CA  HA   sing N N 203 
ARG C   O    doub N N 204 
ARG C   OXT  sing N N 205 
ARG CB  CG   sing N N 206 
ARG CB  HB2  sing N N 207 
ARG CB  HB3  sing N N 208 
ARG CG  CD   sing N N 209 
ARG CG  HG2  sing N N 210 
ARG CG  HG3  sing N N 211 
ARG CD  NE   sing N N 212 
ARG CD  HD2  sing N N 213 
ARG CD  HD3  sing N N 214 
ARG NE  CZ   sing N N 215 
ARG NE  HE   sing N N 216 
ARG CZ  NH1  sing N N 217 
ARG CZ  NH2  doub N N 218 
ARG NH1 HH11 sing N N 219 
ARG NH1 HH12 sing N N 220 
ARG NH2 HH21 sing N N 221 
ARG NH2 HH22 sing N N 222 
ARG OXT HXT  sing N N 223 
ASN N   CA   sing N N 224 
ASN N   H    sing N N 225 
ASN N   H2   sing N N 226 
ASN CA  C    sing N N 227 
ASN CA  CB   sing N N 228 
ASN CA  HA   sing N N 229 
ASN C   O    doub N N 230 
ASN C   OXT  sing N N 231 
ASN CB  CG   sing N N 232 
ASN CB  HB2  sing N N 233 
ASN CB  HB3  sing N N 234 
ASN CG  OD1  doub N N 235 
ASN CG  ND2  sing N N 236 
ASN ND2 HD21 sing N N 237 
ASN ND2 HD22 sing N N 238 
ASN OXT HXT  sing N N 239 
ASP N   CA   sing N N 240 
ASP N   H    sing N N 241 
ASP N   H2   sing N N 242 
ASP CA  C    sing N N 243 
ASP CA  CB   sing N N 244 
ASP CA  HA   sing N N 245 
ASP C   O    doub N N 246 
ASP C   OXT  sing N N 247 
ASP CB  CG   sing N N 248 
ASP CB  HB2  sing N N 249 
ASP CB  HB3  sing N N 250 
ASP CG  OD1  doub N N 251 
ASP CG  OD2  sing N N 252 
ASP OD2 HD2  sing N N 253 
ASP OXT HXT  sing N N 254 
CLR C1  C2   sing N N 255 
CLR C1  C10  sing N N 256 
CLR C1  H11  sing N N 257 
CLR C1  H12  sing N N 258 
CLR C2  C3   sing N N 259 
CLR C2  H21  sing N N 260 
CLR C2  H22  sing N N 261 
CLR C3  C4   sing N N 262 
CLR C3  O1   sing N N 263 
CLR C3  H3   sing N N 264 
CLR C4  C5   sing N N 265 
CLR C4  H41  sing N N 266 
CLR C4  H42  sing N N 267 
CLR C5  C6   doub N N 268 
CLR C5  C10  sing N N 269 
CLR C6  C7   sing N N 270 
CLR C6  H6   sing N N 271 
CLR C7  C8   sing N N 272 
CLR C7  H71  sing N N 273 
CLR C7  H72  sing N N 274 
CLR C8  C9   sing N N 275 
CLR C8  C14  sing N N 276 
CLR C8  H8   sing N N 277 
CLR C9  C10  sing N N 278 
CLR C9  C11  sing N N 279 
CLR C9  H9   sing N N 280 
CLR C10 C19  sing N N 281 
CLR C11 C12  sing N N 282 
CLR C11 H111 sing N N 283 
CLR C11 H112 sing N N 284 
CLR C12 C13  sing N N 285 
CLR C12 H121 sing N N 286 
CLR C12 H122 sing N N 287 
CLR C13 C14  sing N N 288 
CLR C13 C17  sing N N 289 
CLR C13 C18  sing N N 290 
CLR C14 C15  sing N N 291 
CLR C14 H14  sing N N 292 
CLR C15 C16  sing N N 293 
CLR C15 H151 sing N N 294 
CLR C15 H152 sing N N 295 
CLR C16 C17  sing N N 296 
CLR C16 H161 sing N N 297 
CLR C16 H162 sing N N 298 
CLR C17 C20  sing N N 299 
CLR C17 H17  sing N N 300 
CLR C18 H181 sing N N 301 
CLR C18 H182 sing N N 302 
CLR C18 H183 sing N N 303 
CLR C19 H191 sing N N 304 
CLR C19 H192 sing N N 305 
CLR C19 H193 sing N N 306 
CLR C20 C21  sing N N 307 
CLR C20 C22  sing N N 308 
CLR C20 H20  sing N N 309 
CLR C21 H211 sing N N 310 
CLR C21 H212 sing N N 311 
CLR C21 H213 sing N N 312 
CLR C22 C23  sing N N 313 
CLR C22 H221 sing N N 314 
CLR C22 H222 sing N N 315 
CLR C23 C24  sing N N 316 
CLR C23 H231 sing N N 317 
CLR C23 H232 sing N N 318 
CLR C24 C25  sing N N 319 
CLR C24 H241 sing N N 320 
CLR C24 H242 sing N N 321 
CLR C25 C26  sing N N 322 
CLR C25 C27  sing N N 323 
CLR C25 H25  sing N N 324 
CLR C26 H261 sing N N 325 
CLR C26 H262 sing N N 326 
CLR C26 H263 sing N N 327 
CLR C27 H271 sing N N 328 
CLR C27 H272 sing N N 329 
CLR C27 H273 sing N N 330 
CLR O1  H1   sing N N 331 
CYS N   CA   sing N N 332 
CYS N   H    sing N N 333 
CYS N   H2   sing N N 334 
CYS CA  C    sing N N 335 
CYS CA  CB   sing N N 336 
CYS CA  HA   sing N N 337 
CYS C   O    doub N N 338 
CYS C   OXT  sing N N 339 
CYS CB  SG   sing N N 340 
CYS CB  HB2  sing N N 341 
CYS CB  HB3  sing N N 342 
CYS SG  HG   sing N N 343 
CYS OXT HXT  sing N N 344 
GLN N   CA   sing N N 345 
GLN N   H    sing N N 346 
GLN N   H2   sing N N 347 
GLN CA  C    sing N N 348 
GLN CA  CB   sing N N 349 
GLN CA  HA   sing N N 350 
GLN C   O    doub N N 351 
GLN C   OXT  sing N N 352 
GLN CB  CG   sing N N 353 
GLN CB  HB2  sing N N 354 
GLN CB  HB3  sing N N 355 
GLN CG  CD   sing N N 356 
GLN CG  HG2  sing N N 357 
GLN CG  HG3  sing N N 358 
GLN CD  OE1  doub N N 359 
GLN CD  NE2  sing N N 360 
GLN NE2 HE21 sing N N 361 
GLN NE2 HE22 sing N N 362 
GLN OXT HXT  sing N N 363 
GLU N   CA   sing N N 364 
GLU N   H    sing N N 365 
GLU N   H2   sing N N 366 
GLU CA  C    sing N N 367 
GLU CA  CB   sing N N 368 
GLU CA  HA   sing N N 369 
GLU C   O    doub N N 370 
GLU C   OXT  sing N N 371 
GLU CB  CG   sing N N 372 
GLU CB  HB2  sing N N 373 
GLU CB  HB3  sing N N 374 
GLU CG  CD   sing N N 375 
GLU CG  HG2  sing N N 376 
GLU CG  HG3  sing N N 377 
GLU CD  OE1  doub N N 378 
GLU CD  OE2  sing N N 379 
GLU OE2 HE2  sing N N 380 
GLU OXT HXT  sing N N 381 
GLY N   CA   sing N N 382 
GLY N   H    sing N N 383 
GLY N   H2   sing N N 384 
GLY CA  C    sing N N 385 
GLY CA  HA2  sing N N 386 
GLY CA  HA3  sing N N 387 
GLY C   O    doub N N 388 
GLY C   OXT  sing N N 389 
GLY OXT HXT  sing N N 390 
HIS N   CA   sing N N 391 
HIS N   H    sing N N 392 
HIS N   H2   sing N N 393 
HIS CA  C    sing N N 394 
HIS CA  CB   sing N N 395 
HIS CA  HA   sing N N 396 
HIS C   O    doub N N 397 
HIS C   OXT  sing N N 398 
HIS CB  CG   sing N N 399 
HIS CB  HB2  sing N N 400 
HIS CB  HB3  sing N N 401 
HIS CG  ND1  sing Y N 402 
HIS CG  CD2  doub Y N 403 
HIS ND1 CE1  doub Y N 404 
HIS ND1 HD1  sing N N 405 
HIS CD2 NE2  sing Y N 406 
HIS CD2 HD2  sing N N 407 
HIS CE1 NE2  sing Y N 408 
HIS CE1 HE1  sing N N 409 
HIS NE2 HE2  sing N N 410 
HIS OXT HXT  sing N N 411 
HOH O   H1   sing N N 412 
HOH O   H2   sing N N 413 
ILE N   CA   sing N N 414 
ILE N   H    sing N N 415 
ILE N   H2   sing N N 416 
ILE CA  C    sing N N 417 
ILE CA  CB   sing N N 418 
ILE CA  HA   sing N N 419 
ILE C   O    doub N N 420 
ILE C   OXT  sing N N 421 
ILE CB  CG1  sing N N 422 
ILE CB  CG2  sing N N 423 
ILE CB  HB   sing N N 424 
ILE CG1 CD1  sing N N 425 
ILE CG1 HG12 sing N N 426 
ILE CG1 HG13 sing N N 427 
ILE CG2 HG21 sing N N 428 
ILE CG2 HG22 sing N N 429 
ILE CG2 HG23 sing N N 430 
ILE CD1 HD11 sing N N 431 
ILE CD1 HD12 sing N N 432 
ILE CD1 HD13 sing N N 433 
ILE OXT HXT  sing N N 434 
LEU N   CA   sing N N 435 
LEU N   H    sing N N 436 
LEU N   H2   sing N N 437 
LEU CA  C    sing N N 438 
LEU CA  CB   sing N N 439 
LEU CA  HA   sing N N 440 
LEU C   O    doub N N 441 
LEU C   OXT  sing N N 442 
LEU CB  CG   sing N N 443 
LEU CB  HB2  sing N N 444 
LEU CB  HB3  sing N N 445 
LEU CG  CD1  sing N N 446 
LEU CG  CD2  sing N N 447 
LEU CG  HG   sing N N 448 
LEU CD1 HD11 sing N N 449 
LEU CD1 HD12 sing N N 450 
LEU CD1 HD13 sing N N 451 
LEU CD2 HD21 sing N N 452 
LEU CD2 HD22 sing N N 453 
LEU CD2 HD23 sing N N 454 
LEU OXT HXT  sing N N 455 
LYS N   CA   sing N N 456 
LYS N   H    sing N N 457 
LYS N   H2   sing N N 458 
LYS CA  C    sing N N 459 
LYS CA  CB   sing N N 460 
LYS CA  HA   sing N N 461 
LYS C   O    doub N N 462 
LYS C   OXT  sing N N 463 
LYS CB  CG   sing N N 464 
LYS CB  HB2  sing N N 465 
LYS CB  HB3  sing N N 466 
LYS CG  CD   sing N N 467 
LYS CG  HG2  sing N N 468 
LYS CG  HG3  sing N N 469 
LYS CD  CE   sing N N 470 
LYS CD  HD2  sing N N 471 
LYS CD  HD3  sing N N 472 
LYS CE  NZ   sing N N 473 
LYS CE  HE2  sing N N 474 
LYS CE  HE3  sing N N 475 
LYS NZ  HZ1  sing N N 476 
LYS NZ  HZ2  sing N N 477 
LYS NZ  HZ3  sing N N 478 
LYS OXT HXT  sing N N 479 
MET N   CA   sing N N 480 
MET N   H    sing N N 481 
MET N   H2   sing N N 482 
MET CA  C    sing N N 483 
MET CA  CB   sing N N 484 
MET CA  HA   sing N N 485 
MET C   O    doub N N 486 
MET C   OXT  sing N N 487 
MET CB  CG   sing N N 488 
MET CB  HB2  sing N N 489 
MET CB  HB3  sing N N 490 
MET CG  SD   sing N N 491 
MET CG  HG2  sing N N 492 
MET CG  HG3  sing N N 493 
MET SD  CE   sing N N 494 
MET CE  HE1  sing N N 495 
MET CE  HE2  sing N N 496 
MET CE  HE3  sing N N 497 
MET OXT HXT  sing N N 498 
PHE N   CA   sing N N 499 
PHE N   H    sing N N 500 
PHE N   H2   sing N N 501 
PHE CA  C    sing N N 502 
PHE CA  CB   sing N N 503 
PHE CA  HA   sing N N 504 
PHE C   O    doub N N 505 
PHE C   OXT  sing N N 506 
PHE CB  CG   sing N N 507 
PHE CB  HB2  sing N N 508 
PHE CB  HB3  sing N N 509 
PHE CG  CD1  doub Y N 510 
PHE CG  CD2  sing Y N 511 
PHE CD1 CE1  sing Y N 512 
PHE CD1 HD1  sing N N 513 
PHE CD2 CE2  doub Y N 514 
PHE CD2 HD2  sing N N 515 
PHE CE1 CZ   doub Y N 516 
PHE CE1 HE1  sing N N 517 
PHE CE2 CZ   sing Y N 518 
PHE CE2 HE2  sing N N 519 
PHE CZ  HZ   sing N N 520 
PHE OXT HXT  sing N N 521 
PLM C1  O1   sing N N 522 
PLM C1  O2   doub N N 523 
PLM C1  C2   sing N N 524 
PLM O1  H    sing N N 525 
PLM C2  C3   sing N N 526 
PLM C2  H21  sing N N 527 
PLM C2  H22  sing N N 528 
PLM C3  C4   sing N N 529 
PLM C3  H31  sing N N 530 
PLM C3  H32  sing N N 531 
PLM C4  C5   sing N N 532 
PLM C4  H41  sing N N 533 
PLM C4  H42  sing N N 534 
PLM C5  C6   sing N N 535 
PLM C5  H51  sing N N 536 
PLM C5  H52  sing N N 537 
PLM C6  C7   sing N N 538 
PLM C6  H61  sing N N 539 
PLM C6  H62  sing N N 540 
PLM C7  C8   sing N N 541 
PLM C7  H71  sing N N 542 
PLM C7  H72  sing N N 543 
PLM C8  C9   sing N N 544 
PLM C8  H81  sing N N 545 
PLM C8  H82  sing N N 546 
PLM C9  CA   sing N N 547 
PLM C9  H91  sing N N 548 
PLM C9  H92  sing N N 549 
PLM CA  CB   sing N N 550 
PLM CA  HA1  sing N N 551 
PLM CA  HA2  sing N N 552 
PLM CB  CC   sing N N 553 
PLM CB  HB1  sing N N 554 
PLM CB  HB2  sing N N 555 
PLM CC  CD   sing N N 556 
PLM CC  HC1  sing N N 557 
PLM CC  HC2  sing N N 558 
PLM CD  CE   sing N N 559 
PLM CD  HD1  sing N N 560 
PLM CD  HD2  sing N N 561 
PLM CE  CF   sing N N 562 
PLM CE  HE1  sing N N 563 
PLM CE  HE2  sing N N 564 
PLM CF  CG   sing N N 565 
PLM CF  HF1  sing N N 566 
PLM CF  HF2  sing N N 567 
PLM CG  HG1  sing N N 568 
PLM CG  HG2  sing N N 569 
PLM CG  HG3  sing N N 570 
PRO N   CA   sing N N 571 
PRO N   CD   sing N N 572 
PRO N   H    sing N N 573 
PRO CA  C    sing N N 574 
PRO CA  CB   sing N N 575 
PRO CA  HA   sing N N 576 
PRO C   O    doub N N 577 
PRO C   OXT  sing N N 578 
PRO CB  CG   sing N N 579 
PRO CB  HB2  sing N N 580 
PRO CB  HB3  sing N N 581 
PRO CG  CD   sing N N 582 
PRO CG  HG2  sing N N 583 
PRO CG  HG3  sing N N 584 
PRO CD  HD2  sing N N 585 
PRO CD  HD3  sing N N 586 
PRO OXT HXT  sing N N 587 
SER N   CA   sing N N 588 
SER N   H    sing N N 589 
SER N   H2   sing N N 590 
SER CA  C    sing N N 591 
SER CA  CB   sing N N 592 
SER CA  HA   sing N N 593 
SER C   O    doub N N 594 
SER C   OXT  sing N N 595 
SER CB  OG   sing N N 596 
SER CB  HB2  sing N N 597 
SER CB  HB3  sing N N 598 
SER OG  HG   sing N N 599 
SER OXT HXT  sing N N 600 
THR N   CA   sing N N 601 
THR N   H    sing N N 602 
THR N   H2   sing N N 603 
THR CA  C    sing N N 604 
THR CA  CB   sing N N 605 
THR CA  HA   sing N N 606 
THR C   O    doub N N 607 
THR C   OXT  sing N N 608 
THR CB  OG1  sing N N 609 
THR CB  CG2  sing N N 610 
THR CB  HB   sing N N 611 
THR OG1 HG1  sing N N 612 
THR CG2 HG21 sing N N 613 
THR CG2 HG22 sing N N 614 
THR CG2 HG23 sing N N 615 
THR OXT HXT  sing N N 616 
TRP N   CA   sing N N 617 
TRP N   H    sing N N 618 
TRP N   H2   sing N N 619 
TRP CA  C    sing N N 620 
TRP CA  CB   sing N N 621 
TRP CA  HA   sing N N 622 
TRP C   O    doub N N 623 
TRP C   OXT  sing N N 624 
TRP CB  CG   sing N N 625 
TRP CB  HB2  sing N N 626 
TRP CB  HB3  sing N N 627 
TRP CG  CD1  doub Y N 628 
TRP CG  CD2  sing Y N 629 
TRP CD1 NE1  sing Y N 630 
TRP CD1 HD1  sing N N 631 
TRP CD2 CE2  doub Y N 632 
TRP CD2 CE3  sing Y N 633 
TRP NE1 CE2  sing Y N 634 
TRP NE1 HE1  sing N N 635 
TRP CE2 CZ2  sing Y N 636 
TRP CE3 CZ3  doub Y N 637 
TRP CE3 HE3  sing N N 638 
TRP CZ2 CH2  doub Y N 639 
TRP CZ2 HZ2  sing N N 640 
TRP CZ3 CH2  sing Y N 641 
TRP CZ3 HZ3  sing N N 642 
TRP CH2 HH2  sing N N 643 
TRP OXT HXT  sing N N 644 
TYR N   CA   sing N N 645 
TYR N   H    sing N N 646 
TYR N   H2   sing N N 647 
TYR CA  C    sing N N 648 
TYR CA  CB   sing N N 649 
TYR CA  HA   sing N N 650 
TYR C   O    doub N N 651 
TYR C   OXT  sing N N 652 
TYR CB  CG   sing N N 653 
TYR CB  HB2  sing N N 654 
TYR CB  HB3  sing N N 655 
TYR CG  CD1  doub Y N 656 
TYR CG  CD2  sing Y N 657 
TYR CD1 CE1  sing Y N 658 
TYR CD1 HD1  sing N N 659 
TYR CD2 CE2  doub Y N 660 
TYR CD2 HD2  sing N N 661 
TYR CE1 CZ   doub Y N 662 
TYR CE1 HE1  sing N N 663 
TYR CE2 CZ   sing Y N 664 
TYR CE2 HE2  sing N N 665 
TYR CZ  OH   sing N N 666 
TYR OH  HH   sing N N 667 
TYR OXT HXT  sing N N 668 
VAL N   CA   sing N N 669 
VAL N   H    sing N N 670 
VAL N   H2   sing N N 671 
VAL CA  C    sing N N 672 
VAL CA  CB   sing N N 673 
VAL CA  HA   sing N N 674 
VAL C   O    doub N N 675 
VAL C   OXT  sing N N 676 
VAL CB  CG1  sing N N 677 
VAL CB  CG2  sing N N 678 
VAL CB  HB   sing N N 679 
VAL CG1 HG11 sing N N 680 
VAL CG1 HG12 sing N N 681 
VAL CG1 HG13 sing N N 682 
VAL CG2 HG21 sing N N 683 
VAL CG2 HG22 sing N N 684 
VAL CG2 HG23 sing N N 685 
VAL OXT HXT  sing N N 686 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-06 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9INF 
_em_admin.last_update        2025-04-02 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'Cryo-EM structure of human XPR1 in closed state in the presence of KIDINS220-1-432 and 10 mM KH2PO4' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9INF 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ALA A 1 226 ? 208.181 190.977 216.885 1.00 85.57  ? 226 ALA A N   1 
ATOM   2    C CA  . ALA A 1 226 ? 206.953 190.624 216.183 1.00 86.61  ? 226 ALA A CA  1 
ATOM   3    C C   . ALA A 1 226 ? 205.964 191.786 216.196 1.00 87.31  ? 226 ALA A C   1 
ATOM   4    O O   . ALA A 1 226 ? 204.750 191.579 216.205 1.00 85.85  ? 226 ALA A O   1 
ATOM   5    C CB  . ALA A 1 226 ? 206.324 189.386 216.803 1.00 85.81  ? 226 ALA A CB  1 
ATOM   6    N N   . GLN A 1 227 ? 206.493 193.005 216.200 1.00 89.03  ? 227 GLN A N   1 
ATOM   7    C CA  . GLN A 1 227 ? 205.640 194.183 216.193 1.00 91.00  ? 227 GLN A CA  1 
ATOM   8    C C   . GLN A 1 227 ? 204.887 194.278 214.868 1.00 92.27  ? 227 GLN A C   1 
ATOM   9    O O   . GLN A 1 227 ? 205.481 194.088 213.801 1.00 91.32  ? 227 GLN A O   1 
ATOM   10   C CB  . GLN A 1 227 ? 206.469 195.448 216.415 1.00 90.86  ? 227 GLN A CB  1 
ATOM   11   C CG  . GLN A 1 227 ? 207.014 195.593 217.826 1.00 90.88  ? 227 GLN A CG  1 
ATOM   12   C CD  . GLN A 1 227 ? 207.731 196.911 218.041 1.00 89.68  ? 227 GLN A CD  1 
ATOM   13   O OE1 . GLN A 1 227 ? 207.847 197.725 217.125 1.00 88.72  ? 227 GLN A OE1 1 
ATOM   14   N NE2 . GLN A 1 227 ? 208.218 197.129 219.257 1.00 88.98  ? 227 GLN A NE2 1 
ATOM   15   N N   . PRO A 1 228 ? 203.587 194.560 214.900 1.00 83.94  ? 228 PRO A N   1 
ATOM   16   C CA  . PRO A 1 228 ? 202.828 194.667 213.651 1.00 81.12  ? 228 PRO A CA  1 
ATOM   17   C C   . PRO A 1 228 ? 203.283 195.855 212.819 1.00 80.31  ? 228 PRO A C   1 
ATOM   18   O O   . PRO A 1 228 ? 203.723 196.882 213.340 1.00 78.34  ? 228 PRO A O   1 
ATOM   19   C CB  . PRO A 1 228 ? 201.382 194.843 214.127 1.00 77.11  ? 228 PRO A CB  1 
ATOM   20   C CG  . PRO A 1 228 ? 201.508 195.428 215.493 1.00 78.21  ? 228 PRO A CG  1 
ATOM   21   C CD  . PRO A 1 228 ? 202.752 194.826 216.083 1.00 79.35  ? 228 PRO A CD  1 
ATOM   22   N N   . ALA A 1 229 ? 203.171 195.699 211.505 1.00 77.19  ? 229 ALA A N   1 
ATOM   23   C CA  . ALA A 1 229 ? 203.561 196.742 210.574 1.00 73.26  ? 229 ALA A CA  1 
ATOM   24   C C   . ALA A 1 229 ? 202.496 197.832 210.509 1.00 68.77  ? 229 ALA A C   1 
ATOM   25   O O   . ALA A 1 229 ? 201.327 197.592 210.824 1.00 69.18  ? 229 ALA A O   1 
ATOM   26   C CB  . ALA A 1 229 ? 203.790 196.147 209.189 1.00 71.54  ? 229 ALA A CB  1 
ATOM   27   N N   . PRO A 1 230 ? 202.877 199.046 210.112 1.00 61.82  ? 230 PRO A N   1 
ATOM   28   C CA  . PRO A 1 230 ? 201.878 200.106 209.936 1.00 61.37  ? 230 PRO A CA  1 
ATOM   29   C C   . PRO A 1 230 ? 200.866 199.736 208.862 1.00 60.32  ? 230 PRO A C   1 
ATOM   30   O O   . PRO A 1 230 ? 201.166 198.997 207.922 1.00 66.57  ? 230 PRO A O   1 
ATOM   31   C CB  . PRO A 1 230 ? 202.714 201.323 209.522 1.00 57.97  ? 230 PRO A CB  1 
ATOM   32   C CG  . PRO A 1 230 ? 204.089 201.030 210.015 1.00 62.65  ? 230 PRO A CG  1 
ATOM   33   C CD  . PRO A 1 230 ? 204.252 199.544 209.932 1.00 60.25  ? 230 PRO A CD  1 
ATOM   34   N N   . ALA A 1 231 ? 199.647 200.255 209.023 1.00 46.25  ? 231 ALA A N   1 
ATOM   35   C CA  . ALA A 1 231 ? 198.580 199.944 208.076 1.00 49.86  ? 231 ALA A CA  1 
ATOM   36   C C   . ALA A 1 231 ? 198.911 200.455 206.680 1.00 49.37  ? 231 ALA A C   1 
ATOM   37   O O   . ALA A 1 231 ? 198.578 199.809 205.678 1.00 51.13  ? 231 ALA A O   1 
ATOM   38   C CB  . ALA A 1 231 ? 197.256 200.531 208.566 1.00 50.36  ? 231 ALA A CB  1 
ATOM   39   N N   . TRP A 1 232 ? 199.566 201.615 206.589 1.00 42.95  ? 232 TRP A N   1 
ATOM   40   C CA  . TRP A 1 232 ? 199.928 202.136 205.277 1.00 45.32  ? 232 TRP A CA  1 
ATOM   41   C C   . TRP A 1 232 ? 200.965 201.261 204.589 1.00 51.20  ? 232 TRP A C   1 
ATOM   42   O O   . TRP A 1 232 ? 200.995 201.198 203.357 1.00 40.72  ? 232 TRP A O   1 
ATOM   43   C CB  . TRP A 1 232 ? 200.437 203.572 205.385 1.00 41.00  ? 232 TRP A CB  1 
ATOM   44   C CG  . TRP A 1 232 ? 200.043 204.398 204.201 1.00 43.91  ? 232 TRP A CG  1 
ATOM   45   C CD1 . TRP A 1 232 ? 200.536 204.295 202.933 1.00 52.87  ? 232 TRP A CD1 1 
ATOM   46   C CD2 . TRP A 1 232 ? 199.067 205.445 204.167 1.00 40.51  ? 232 TRP A CD2 1 
ATOM   47   N NE1 . TRP A 1 232 ? 199.929 205.213 202.113 1.00 47.34  ? 232 TRP A NE1 1 
ATOM   48   C CE2 . TRP A 1 232 ? 199.024 205.933 202.847 1.00 45.37  ? 232 TRP A CE2 1 
ATOM   49   C CE3 . TRP A 1 232 ? 198.228 206.019 205.126 1.00 40.71  ? 232 TRP A CE3 1 
ATOM   50   C CZ2 . TRP A 1 232 ? 198.176 206.967 202.460 1.00 43.36  ? 232 TRP A CZ2 1 
ATOM   51   C CZ3 . TRP A 1 232 ? 197.387 207.045 204.740 1.00 50.45  ? 232 TRP A CZ3 1 
ATOM   52   C CH2 . TRP A 1 232 ? 197.367 207.509 203.419 1.00 47.77  ? 232 TRP A CH2 1 
ATOM   53   N N   . THR A 1 233 ? 201.818 200.576 205.354 1.00 50.58  ? 233 THR A N   1 
ATOM   54   C CA  . THR A 1 233 ? 202.749 199.635 204.740 1.00 35.63  ? 233 THR A CA  1 
ATOM   55   C C   . THR A 1 233 ? 202.002 198.486 204.071 1.00 39.47  ? 233 THR A C   1 
ATOM   56   O O   . THR A 1 233 ? 202.321 198.102 202.938 1.00 56.08  ? 233 THR A O   1 
ATOM   57   C CB  . THR A 1 233 ? 203.730 199.107 205.787 1.00 43.02  ? 233 THR A CB  1 
ATOM   58   O OG1 . THR A 1 233 ? 204.686 200.127 206.103 1.00 54.84  ? 233 THR A OG1 1 
ATOM   59   C CG2 . THR A 1 233 ? 204.466 197.884 205.266 1.00 44.42  ? 233 THR A CG2 1 
ATOM   60   N N   . THR A 1 234 ? 200.993 197.937 204.751 1.00 19.69  ? 234 THR A N   1 
ATOM   61   C CA  . THR A 1 234 ? 200.177 196.889 204.147 1.00 16.50  ? 234 THR A CA  1 
ATOM   62   C C   . THR A 1 234 ? 199.420 197.414 202.934 1.00 22.23  ? 234 THR A C   1 
ATOM   63   O O   . THR A 1 234 ? 199.283 196.713 201.924 1.00 24.91  ? 234 THR A O   1 
ATOM   64   C CB  . THR A 1 234 ? 199.205 196.316 205.177 1.00 14.63  ? 234 THR A CB  1 
ATOM   65   O OG1 . THR A 1 234 ? 199.858 196.219 206.449 1.00 24.63  ? 234 THR A OG1 1 
ATOM   66   C CG2 . THR A 1 234 ? 198.739 194.936 204.753 1.00 23.62  ? 234 THR A CG2 1 
ATOM   67   N N   . PHE A 1 235 ? 198.918 198.647 203.016 1.00 31.31  ? 235 PHE A N   1 
ATOM   68   C CA  . PHE A 1 235 ? 198.260 199.245 201.858 1.00 29.52  ? 235 PHE A CA  1 
ATOM   69   C C   . PHE A 1 235 ? 199.222 199.365 200.684 1.00 32.22  ? 235 PHE A C   1 
ATOM   70   O O   . PHE A 1 235 ? 198.842 199.124 199.533 1.00 43.40  ? 235 PHE A O   1 
ATOM   71   C CB  . PHE A 1 235 ? 197.685 200.613 202.223 1.00 35.80  ? 235 PHE A CB  1 
ATOM   72   C CG  . PHE A 1 235 ? 197.385 201.479 201.034 1.00 32.34  ? 235 PHE A CG  1 
ATOM   73   C CD1 . PHE A 1 235 ? 196.246 201.267 200.278 1.00 23.71  ? 235 PHE A CD1 1 
ATOM   74   C CD2 . PHE A 1 235 ? 198.240 202.507 200.673 1.00 30.16  ? 235 PHE A CD2 1 
ATOM   75   C CE1 . PHE A 1 235 ? 195.967 202.058 199.183 1.00 24.29  ? 235 PHE A CE1 1 
ATOM   76   C CE2 . PHE A 1 235 ? 197.966 203.302 199.579 1.00 24.62  ? 235 PHE A CE2 1 
ATOM   77   C CZ  . PHE A 1 235 ? 196.828 203.078 198.834 1.00 30.94  ? 235 PHE A CZ  1 
ATOM   78   N N   . ARG A 1 236 ? 200.472 199.744 200.954 1.00 26.37  ? 236 ARG A N   1 
ATOM   79   C CA  . ARG A 1 236 ? 201.461 199.869 199.889 1.00 34.36  ? 236 ARG A CA  1 
ATOM   80   C C   . ARG A 1 236 ? 201.787 198.517 199.268 1.00 33.95  ? 236 ARG A C   1 
ATOM   81   O O   . ARG A 1 236 ? 201.915 198.410 198.042 1.00 38.07  ? 236 ARG A O   1 
ATOM   82   C CB  . ARG A 1 236 ? 202.727 200.535 200.425 1.00 28.92  ? 236 ARG A CB  1 
ATOM   83   C CG  . ARG A 1 236 ? 202.800 202.027 200.158 1.00 28.08  ? 236 ARG A CG  1 
ATOM   84   C CD  . ARG A 1 236 ? 204.018 202.646 200.817 1.00 24.73  ? 236 ARG A CD  1 
ATOM   85   N NE  . ARG A 1 236 ? 204.037 202.404 202.254 1.00 39.57  ? 236 ARG A NE  1 
ATOM   86   C CZ  . ARG A 1 236 ? 204.964 202.868 203.080 1.00 44.41  ? 236 ARG A CZ  1 
ATOM   87   N NH1 . ARG A 1 236 ? 205.968 203.612 202.644 1.00 43.98  ? 236 ARG A NH1 1 
ATOM   88   N NH2 . ARG A 1 236 ? 204.883 202.578 204.375 1.00 38.91  ? 236 ARG A NH2 1 
ATOM   89   N N   . VAL A 1 237 ? 201.936 197.474 200.090 1.00 31.72  ? 237 VAL A N   1 
ATOM   90   C CA  . VAL A 1 237 ? 202.220 196.158 199.520 1.00 28.43  ? 237 VAL A CA  1 
ATOM   91   C C   . VAL A 1 237 ? 201.031 195.667 198.703 1.00 30.94  ? 237 VAL A C   1 
ATOM   92   O O   . VAL A 1 237 ? 201.206 195.038 197.654 1.00 39.26  ? 237 VAL A O   1 
ATOM   93   C CB  . VAL A 1 237 ? 202.637 195.139 200.604 1.00 11.47  ? 237 VAL A CB  1 
ATOM   94   C CG1 . VAL A 1 237 ? 203.645 195.745 201.554 1.00 17.68  ? 237 VAL A CG1 1 
ATOM   95   C CG2 . VAL A 1 237 ? 201.442 194.580 201.359 1.00 32.96  ? 237 VAL A CG2 1 
ATOM   96   N N   . GLY A 1 238 ? 199.808 195.977 199.140 1.00 20.71  ? 238 GLY A N   1 
ATOM   97   C CA  . GLY A 1 238 ? 198.645 195.616 198.347 1.00 30.72  ? 238 GLY A CA  1 
ATOM   98   C C   . GLY A 1 238 ? 198.583 196.363 197.029 1.00 30.66  ? 238 GLY A C   1 
ATOM   99   O O   . GLY A 1 238 ? 198.278 195.778 195.985 1.00 26.63  ? 238 GLY A O   1 
ATOM   100  N N   . LEU A 1 239 ? 198.876 197.664 197.058 1.00 16.43  ? 239 LEU A N   1 
ATOM   101  C CA  . LEU A 1 239 ? 198.888 198.460 195.835 1.00 15.95  ? 239 LEU A CA  1 
ATOM   102  C C   . LEU A 1 239 ? 199.921 197.927 194.852 1.00 32.86  ? 239 LEU A C   1 
ATOM   103  O O   . LEU A 1 239 ? 199.641 197.775 193.656 1.00 44.05  ? 239 LEU A O   1 
ATOM   104  C CB  . LEU A 1 239 ? 199.168 199.924 196.178 1.00 18.12  ? 239 LEU A CB  1 
ATOM   105  C CG  . LEU A 1 239 ? 199.530 200.880 195.041 1.00 29.54  ? 239 LEU A CG  1 
ATOM   106  C CD1 . LEU A 1 239 ? 198.280 201.491 194.434 1.00 38.99  ? 239 LEU A CD1 1 
ATOM   107  C CD2 . LEU A 1 239 ? 200.472 201.964 195.536 1.00 26.86  ? 239 LEU A CD2 1 
ATOM   108  N N   . PHE A 1 240 ? 201.123 197.626 195.346 1.00 25.05  ? 240 PHE A N   1 
ATOM   109  C CA  . PHE A 1 240 ? 202.163 197.090 194.477 1.00 18.56  ? 240 PHE A CA  1 
ATOM   110  C C   . PHE A 1 240 ? 201.786 195.713 193.946 1.00 20.09  ? 240 PHE A C   1 
ATOM   111  O O   . PHE A 1 240 ? 202.043 195.407 192.779 1.00 30.90  ? 240 PHE A O   1 
ATOM   112  C CB  . PHE A 1 240 ? 203.497 197.045 195.217 1.00 25.91  ? 240 PHE A CB  1 
ATOM   113  C CG  . PHE A 1 240 ? 204.084 198.401 195.484 1.00 25.32  ? 240 PHE A CG  1 
ATOM   114  C CD1 . PHE A 1 240 ? 203.953 199.418 194.554 1.00 25.54  ? 240 PHE A CD1 1 
ATOM   115  C CD2 . PHE A 1 240 ? 204.769 198.659 196.658 1.00 33.13  ? 240 PHE A CD2 1 
ATOM   116  C CE1 . PHE A 1 240 ? 204.491 200.667 194.792 1.00 29.61  ? 240 PHE A CE1 1 
ATOM   117  C CE2 . PHE A 1 240 ? 205.310 199.907 196.901 1.00 26.57  ? 240 PHE A CE2 1 
ATOM   118  C CZ  . PHE A 1 240 ? 205.171 200.912 195.967 1.00 24.52  ? 240 PHE A CZ  1 
ATOM   119  N N   . CYS A 1 241 ? 201.161 194.876 194.778 1.00 25.97  ? 241 CYS A N   1 
ATOM   120  C CA  . CYS A 1 241 ? 200.718 193.563 194.319 1.00 28.04  ? 241 CYS A CA  1 
ATOM   121  C C   . CYS A 1 241 ? 199.686 193.686 193.204 1.00 26.35  ? 241 CYS A C   1 
ATOM   122  O O   . CYS A 1 241 ? 199.749 192.963 192.203 1.00 38.11  ? 241 CYS A O   1 
ATOM   123  C CB  . CYS A 1 241 ? 200.147 192.767 195.491 1.00 41.53  ? 241 CYS A CB  1 
ATOM   124  S SG  . CYS A 1 241 ? 199.340 191.225 195.012 1.00 56.54  ? 241 CYS A SG  1 
ATOM   125  N N   . GLY A 1 242 ? 198.721 194.592 193.365 1.00 19.95  ? 242 GLY A N   1 
ATOM   126  C CA  . GLY A 1 242 ? 197.710 194.768 192.335 1.00 31.76  ? 242 GLY A CA  1 
ATOM   127  C C   . GLY A 1 242 ? 198.284 195.312 191.041 1.00 24.70  ? 242 GLY A C   1 
ATOM   128  O O   . GLY A 1 242 ? 197.971 194.815 189.950 1.00 21.17  ? 242 GLY A O   1 
ATOM   129  N N   . ILE A 1 243 ? 199.142 196.330 191.142 1.00 23.87  ? 243 ILE A N   1 
ATOM   130  C CA  . ILE A 1 243 ? 199.783 196.867 189.948 1.00 26.47  ? 243 ILE A CA  1 
ATOM   131  C C   . ILE A 1 243 ? 200.605 195.783 189.265 1.00 37.66  ? 243 ILE A C   1 
ATOM   132  O O   . ILE A 1 243 ? 200.586 195.654 188.036 1.00 34.08  ? 243 ILE A O   1 
ATOM   133  C CB  . ILE A 1 243 ? 200.638 198.098 190.304 1.00 23.37  ? 243 ILE A CB  1 
ATOM   134  C CG1 . ILE A 1 243 ? 199.761 199.213 190.873 1.00 25.73  ? 243 ILE A CG1 1 
ATOM   135  C CG2 . ILE A 1 243 ? 201.372 198.612 189.078 1.00 28.98  ? 243 ILE A CG2 1 
ATOM   136  C CD1 . ILE A 1 243 ? 200.536 200.437 191.312 1.00 31.30  ? 243 ILE A CD1 1 
ATOM   137  N N   . PHE A 1 244 ? 201.306 194.960 190.051 1.00 41.37  ? 244 PHE A N   1 
ATOM   138  C CA  . PHE A 1 244 ? 202.148 193.916 189.482 1.00 25.47  ? 244 PHE A CA  1 
ATOM   139  C C   . PHE A 1 244 ? 201.324 192.842 188.788 1.00 34.06  ? 244 PHE A C   1 
ATOM   140  O O   . PHE A 1 244 ? 201.687 192.394 187.697 1.00 47.52  ? 244 PHE A O   1 
ATOM   141  C CB  . PHE A 1 244 ? 203.024 193.296 190.570 1.00 30.67  ? 244 PHE A CB  1 
ATOM   142  C CG  . PHE A 1 244 ? 204.040 192.323 190.046 1.00 31.54  ? 244 PHE A CG  1 
ATOM   143  C CD1 . PHE A 1 244 ? 205.086 192.757 189.251 1.00 32.02  ? 244 PHE A CD1 1 
ATOM   144  C CD2 . PHE A 1 244 ? 203.950 190.976 190.349 1.00 36.19  ? 244 PHE A CD2 1 
ATOM   145  C CE1 . PHE A 1 244 ? 206.023 191.866 188.766 1.00 34.64  ? 244 PHE A CE1 1 
ATOM   146  C CE2 . PHE A 1 244 ? 204.884 190.080 189.867 1.00 37.82  ? 244 PHE A CE2 1 
ATOM   147  C CZ  . PHE A 1 244 ? 205.921 190.526 189.075 1.00 35.96  ? 244 PHE A CZ  1 
ATOM   148  N N   . ILE A 1 245 ? 200.218 192.410 189.395 1.00 35.61  ? 245 ILE A N   1 
ATOM   149  C CA  . ILE A 1 245 ? 199.435 191.346 188.774 1.00 37.49  ? 245 ILE A CA  1 
ATOM   150  C C   . ILE A 1 245 ? 198.765 191.849 187.500 1.00 43.01  ? 245 ILE A C   1 
ATOM   151  O O   . ILE A 1 245 ? 198.725 191.139 186.484 1.00 50.04  ? 245 ILE A O   1 
ATOM   152  C CB  . ILE A 1 245 ? 198.420 190.747 189.768 1.00 31.71  ? 245 ILE A CB  1 
ATOM   153  C CG1 . ILE A 1 245 ? 197.642 189.607 189.108 1.00 34.45  ? 245 ILE A CG1 1 
ATOM   154  C CG2 . ILE A 1 245 ? 197.457 191.794 190.286 1.00 37.65  ? 245 ILE A CG2 1 
ATOM   155  C CD1 . ILE A 1 245 ? 196.498 189.082 189.945 1.00 40.55  ? 245 ILE A CD1 1 
ATOM   156  N N   . VAL A 1 246 ? 198.260 193.087 187.508 1.00 34.53  ? 246 VAL A N   1 
ATOM   157  C CA  . VAL A 1 246 ? 197.635 193.602 186.293 1.00 24.61  ? 246 VAL A CA  1 
ATOM   158  C C   . VAL A 1 246 ? 198.681 193.822 185.207 1.00 30.45  ? 246 VAL A C   1 
ATOM   159  O O   . VAL A 1 246 ? 198.446 193.520 184.030 1.00 35.75  ? 246 VAL A O   1 
ATOM   160  C CB  . VAL A 1 246 ? 196.842 194.885 186.588 1.00 28.90  ? 246 VAL A CB  1 
ATOM   161  C CG1 . VAL A 1 246 ? 196.244 195.433 185.305 1.00 28.15  ? 246 VAL A CG1 1 
ATOM   162  C CG2 . VAL A 1 246 ? 195.756 194.599 187.591 1.00 43.10  ? 246 VAL A CG2 1 
ATOM   163  N N   . LEU A 1 247 ? 199.856 194.340 185.579 1.00 39.34  ? 247 LEU A N   1 
ATOM   164  C CA  . LEU A 1 247 ? 200.927 194.519 184.609 1.00 36.56  ? 247 LEU A CA  1 
ATOM   165  C C   . LEU A 1 247 ? 201.409 193.186 184.054 1.00 43.41  ? 247 LEU A C   1 
ATOM   166  O O   . LEU A 1 247 ? 201.755 193.102 182.874 1.00 50.14  ? 247 LEU A O   1 
ATOM   167  C CB  . LEU A 1 247 ? 202.087 195.281 185.248 1.00 31.31  ? 247 LEU A CB  1 
ATOM   168  C CG  . LEU A 1 247 ? 201.973 196.805 185.232 1.00 23.96  ? 247 LEU A CG  1 
ATOM   169  C CD1 . LEU A 1 247 ? 203.162 197.440 185.930 1.00 34.66  ? 247 LEU A CD1 1 
ATOM   170  C CD2 . LEU A 1 247 ? 201.854 197.310 183.808 1.00 30.04  ? 247 LEU A CD2 1 
ATOM   171  N N   . ASN A 1 248 ? 201.431 192.138 184.877 1.00 43.83  ? 248 ASN A N   1 
ATOM   172  C CA  . ASN A 1 248 ? 201.841 190.823 184.396 1.00 37.02  ? 248 ASN A CA  1 
ATOM   173  C C   . ASN A 1 248 ? 200.809 190.241 183.439 1.00 47.33  ? 248 ASN A C   1 
ATOM   174  O O   . ASN A 1 248 ? 201.169 189.621 182.432 1.00 52.49  ? 248 ASN A O   1 
ATOM   175  C CB  . ASN A 1 248 ? 202.072 189.885 185.580 1.00 41.42  ? 248 ASN A CB  1 
ATOM   176  C CG  . ASN A 1 248 ? 203.079 188.798 185.273 1.00 58.15  ? 248 ASN A CG  1 
ATOM   177  O OD1 . ASN A 1 248 ? 202.863 187.964 184.393 1.00 62.08  ? 248 ASN A OD1 1 
ATOM   178  N ND2 . ASN A 1 248 ? 204.192 188.800 185.998 1.00 59.85  ? 248 ASN A ND2 1 
ATOM   179  N N   . ILE A 1 249 ? 199.520 190.431 183.733 1.00 40.25  ? 249 ILE A N   1 
ATOM   180  C CA  . ILE A 1 249 ? 198.483 189.988 182.804 1.00 36.27  ? 249 ILE A CA  1 
ATOM   181  C C   . ILE A 1 249 ? 198.605 190.737 181.481 1.00 37.86  ? 249 ILE A C   1 
ATOM   182  O O   . ILE A 1 249 ? 198.498 190.145 180.398 1.00 42.00  ? 249 ILE A O   1 
ATOM   183  C CB  . ILE A 1 249 ? 197.089 190.163 183.435 1.00 37.11  ? 249 ILE A CB  1 
ATOM   184  C CG1 . ILE A 1 249 ? 196.822 189.048 184.448 1.00 41.70  ? 249 ILE A CG1 1 
ATOM   185  C CG2 . ILE A 1 249 ? 196.012 190.173 182.361 1.00 41.29  ? 249 ILE A CG2 1 
ATOM   186  C CD1 . ILE A 1 249 ? 195.377 188.947 184.888 1.00 44.55  ? 249 ILE A CD1 1 
ATOM   187  N N   . THR A 1 250 ? 198.845 192.048 181.550 1.00 38.83  ? 250 THR A N   1 
ATOM   188  C CA  . THR A 1 250 ? 199.035 192.836 180.336 1.00 37.74  ? 250 THR A CA  1 
ATOM   189  C C   . THR A 1 250 ? 200.269 192.374 179.570 1.00 44.77  ? 250 THR A C   1 
ATOM   190  O O   . THR A 1 250 ? 200.261 192.329 178.336 1.00 47.31  ? 250 THR A O   1 
ATOM   191  C CB  . THR A 1 250 ? 199.140 194.321 180.690 1.00 41.39  ? 250 THR A CB  1 
ATOM   192  O OG1 . THR A 1 250 ? 197.852 194.809 181.084 1.00 50.72  ? 250 THR A OG1 1 
ATOM   193  C CG2 . THR A 1 250 ? 199.625 195.127 179.498 1.00 43.10  ? 250 THR A CG2 1 
ATOM   194  N N   . LEU A 1 251 ? 201.339 192.027 180.287 1.00 46.84  ? 251 LEU A N   1 
ATOM   195  C CA  . LEU A 1 251 ? 202.549 191.523 179.646 1.00 44.46  ? 251 LEU A CA  1 
ATOM   196  C C   . LEU A 1 251 ? 202.289 190.205 178.930 1.00 40.91  ? 251 LEU A C   1 
ATOM   197  O O   . LEU A 1 251 ? 202.775 189.990 177.815 1.00 53.14  ? 251 LEU A O   1 
ATOM   198  C CB  . LEU A 1 251 ? 203.654 191.358 180.690 1.00 44.65  ? 251 LEU A CB  1 
ATOM   199  C CG  . LEU A 1 251 ? 204.850 192.303 180.596 1.00 40.75  ? 251 LEU A CG  1 
ATOM   200  C CD1 . LEU A 1 251 ? 205.896 191.923 181.623 1.00 40.11  ? 251 LEU A CD1 1 
ATOM   201  C CD2 . LEU A 1 251 ? 205.438 192.270 179.196 1.00 41.14  ? 251 LEU A CD2 1 
ATOM   202  N N   . VAL A 1 252 ? 201.530 189.307 179.561 1.00 31.17  ? 252 VAL A N   1 
ATOM   203  C CA  . VAL A 1 252 ? 201.187 188.039 178.918 1.00 30.42  ? 252 VAL A CA  1 
ATOM   204  C C   . VAL A 1 252 ? 200.361 188.290 177.662 1.00 45.20  ? 252 VAL A C   1 
ATOM   205  O O   . VAL A 1 252 ? 200.600 187.686 176.607 1.00 50.35  ? 252 VAL A O   1 
ATOM   206  C CB  . VAL A 1 252 ? 200.450 187.115 179.904 1.00 28.97  ? 252 VAL A CB  1 
ATOM   207  C CG1 . VAL A 1 252 ? 199.975 185.859 179.195 1.00 27.75  ? 252 VAL A CG1 1 
ATOM   208  C CG2 . VAL A 1 252 ? 201.359 186.752 181.064 1.00 39.37  ? 252 VAL A CG2 1 
ATOM   209  N N   . LEU A 1 253 ? 199.377 189.189 177.754 1.00 51.52  ? 253 LEU A N   1 
ATOM   210  C CA  . LEU A 1 253 ? 198.554 189.500 176.588 1.00 44.29  ? 253 LEU A CA  1 
ATOM   211  C C   . LEU A 1 253 ? 199.387 190.113 175.467 1.00 47.26  ? 253 LEU A C   1 
ATOM   212  O O   . LEU A 1 253 ? 199.190 189.791 174.289 1.00 54.07  ? 253 LEU A O   1 
ATOM   213  C CB  . LEU A 1 253 ? 197.411 190.436 176.982 1.00 40.99  ? 253 LEU A CB  1 
ATOM   214  C CG  . LEU A 1 253 ? 196.075 189.792 177.367 1.00 48.22  ? 253 LEU A CG  1 
ATOM   215  C CD1 . LEU A 1 253 ? 195.475 189.069 176.174 1.00 46.01  ? 253 LEU A CD1 1 
ATOM   216  C CD2 . LEU A 1 253 ? 196.221 188.845 178.547 1.00 49.25  ? 253 LEU A CD2 1 
ATOM   217  N N   . ALA A 1 254 ? 200.316 191.005 175.815 1.00 45.11  ? 254 ALA A N   1 
ATOM   218  C CA  . ALA A 1 254 ? 201.177 191.621 174.811 1.00 48.93  ? 254 ALA A CA  1 
ATOM   219  C C   . ALA A 1 254 ? 202.088 190.591 174.159 1.00 50.48  ? 254 ALA A C   1 
ATOM   220  O O   . ALA A 1 254 ? 202.301 190.624 172.944 1.00 57.01  ? 254 ALA A O   1 
ATOM   221  C CB  . ALA A 1 254 ? 201.998 192.744 175.442 1.00 41.80  ? 254 ALA A CB  1 
ATOM   222  N N   . ALA A 1 255 ? 202.635 189.667 174.950 1.00 45.04  ? 255 ALA A N   1 
ATOM   223  C CA  . ALA A 1 255 ? 203.456 188.605 174.381 1.00 47.00  ? 255 ALA A CA  1 
ATOM   224  C C   . ALA A 1 255 ? 202.642 187.730 173.440 1.00 50.40  ? 255 ALA A C   1 
ATOM   225  O O   . ALA A 1 255 ? 203.136 187.308 172.388 1.00 56.92  ? 255 ALA A O   1 
ATOM   226  C CB  . ALA A 1 255 ? 204.079 187.766 175.496 1.00 49.27  ? 255 ALA A CB  1 
ATOM   227  N N   . VAL A 1 256 ? 201.391 187.444 173.803 1.00 44.32  ? 256 VAL A N   1 
ATOM   228  C CA  . VAL A 1 256 ? 200.549 186.605 172.957 1.00 49.35  ? 256 VAL A CA  1 
ATOM   229  C C   . VAL A 1 256 ? 200.216 187.312 171.647 1.00 53.84  ? 256 VAL A C   1 
ATOM   230  O O   . VAL A 1 256 ? 200.312 186.717 170.566 1.00 56.10  ? 256 VAL A O   1 
ATOM   231  C CB  . VAL A 1 256 ? 199.277 186.189 173.719 1.00 45.66  ? 256 VAL A CB  1 
ATOM   232  C CG1 . VAL A 1 256 ? 198.238 185.631 172.759 1.00 50.68  ? 256 VAL A CG1 1 
ATOM   233  C CG2 . VAL A 1 256 ? 199.614 185.168 174.792 1.00 46.56  ? 256 VAL A CG2 1 
ATOM   234  N N   . PHE A 1 257 ? 199.831 188.588 171.711 1.00 52.35  ? 257 PHE A N   1 
ATOM   235  C CA  . PHE A 1 257 ? 199.276 189.278 170.548 1.00 53.08  ? 257 PHE A CA  1 
ATOM   236  C C   . PHE A 1 257 ? 200.296 190.149 169.820 1.00 58.03  ? 257 PHE A C   1 
ATOM   237  O O   . PHE A 1 257 ? 200.556 189.939 168.632 1.00 67.56  ? 257 PHE A O   1 
ATOM   238  C CB  . PHE A 1 257 ? 198.067 190.121 170.975 1.00 50.65  ? 257 PHE A CB  1 
ATOM   239  C CG  . PHE A 1 257 ? 196.836 189.312 171.259 1.00 57.64  ? 257 PHE A CG  1 
ATOM   240  C CD1 . PHE A 1 257 ? 196.432 188.315 170.388 1.00 58.19  ? 257 PHE A CD1 1 
ATOM   241  C CD2 . PHE A 1 257 ? 196.084 189.544 172.398 1.00 58.19  ? 257 PHE A CD2 1 
ATOM   242  C CE1 . PHE A 1 257 ? 195.300 187.566 170.645 1.00 57.76  ? 257 PHE A CE1 1 
ATOM   243  C CE2 . PHE A 1 257 ? 194.950 188.798 172.660 1.00 56.31  ? 257 PHE A CE2 1 
ATOM   244  C CZ  . PHE A 1 257 ? 194.558 187.808 171.782 1.00 56.47  ? 257 PHE A CZ  1 
ATOM   245  N N   . LYS A 1 258 ? 200.881 191.128 170.509 1.00 60.24  ? 258 LYS A N   1 
ATOM   246  C CA  . LYS A 1 258 ? 201.783 192.091 169.878 1.00 64.96  ? 258 LYS A CA  1 
ATOM   247  C C   . LYS A 1 258 ? 203.225 191.662 170.134 1.00 69.00  ? 258 LYS A C   1 
ATOM   248  O O   . LYS A 1 258 ? 203.896 192.135 171.051 1.00 75.72  ? 258 LYS A O   1 
ATOM   249  C CB  . LYS A 1 258 ? 201.513 193.500 170.394 1.00 64.46  ? 258 LYS A CB  1 
ATOM   250  C CG  . LYS A 1 258 ? 202.203 194.587 169.587 1.00 70.99  ? 258 LYS A CG  1 
ATOM   251  C CD  . LYS A 1 258 ? 201.766 195.974 170.025 1.00 75.20  ? 258 LYS A CD  1 
ATOM   252  C CE  . LYS A 1 258 ? 202.487 197.050 169.229 1.00 73.18  ? 258 LYS A CE  1 
ATOM   253  N NZ  . LYS A 1 258 ? 202.161 198.418 169.717 1.00 71.05  ? 258 LYS A NZ  1 
ATOM   254  N N   . LEU A 1 259 ? 203.702 190.746 169.296 1.00 82.41  ? 259 LEU A N   1 
ATOM   255  C CA  . LEU A 1 259 ? 205.091 190.314 169.335 1.00 84.98  ? 259 LEU A CA  1 
ATOM   256  C C   . LEU A 1 259 ? 205.500 189.882 167.936 1.00 84.67  ? 259 LEU A C   1 
ATOM   257  O O   . LEU A 1 259 ? 204.707 189.275 167.211 1.00 82.63  ? 259 LEU A O   1 
ATOM   258  C CB  . LEU A 1 259 ? 205.301 189.171 170.335 1.00 82.82  ? 259 LEU A CB  1 
ATOM   259  C CG  . LEU A 1 259 ? 206.747 188.734 170.576 1.00 82.33  ? 259 LEU A CG  1 
ATOM   260  C CD1 . LEU A 1 259 ? 207.602 189.917 171.004 1.00 77.45  ? 259 LEU A CD1 1 
ATOM   261  C CD2 . LEU A 1 259 ? 206.808 187.623 171.612 1.00 81.58  ? 259 LEU A CD2 1 
ATOM   262  N N   . GLU A 1 260 ? 206.736 190.198 167.563 1.00 103.04 ? 260 GLU A N   1 
ATOM   263  C CA  . GLU A 1 260 ? 207.254 189.896 166.236 1.00 102.53 ? 260 GLU A CA  1 
ATOM   264  C C   . GLU A 1 260 ? 208.093 188.627 166.291 1.00 104.87 ? 260 GLU A C   1 
ATOM   265  O O   . GLU A 1 260 ? 209.017 188.522 167.104 1.00 105.50 ? 260 GLU A O   1 
ATOM   266  C CB  . GLU A 1 260 ? 208.088 191.060 165.698 1.00 102.29 ? 260 GLU A CB  1 
ATOM   267  C CG  . GLU A 1 260 ? 207.433 192.426 165.842 1.00 102.75 ? 260 GLU A CG  1 
ATOM   268  C CD  . GLU A 1 260 ? 207.804 193.119 167.139 1.00 104.50 ? 260 GLU A CD  1 
ATOM   269  O OE1 . GLU A 1 260 ? 207.502 192.567 168.218 1.00 103.79 ? 260 GLU A OE1 1 
ATOM   270  O OE2 . GLU A 1 260 ? 208.398 194.216 167.079 1.00 104.34 ? 260 GLU A OE2 1 
ATOM   271  N N   . THR A 1 261 ? 207.769 187.668 165.423 1.00 119.20 ? 261 THR A N   1 
ATOM   272  C CA  . THR A 1 261 ? 208.483 186.400 165.366 1.00 119.57 ? 261 THR A CA  1 
ATOM   273  C C   . THR A 1 261 ? 209.674 186.425 164.418 1.00 120.35 ? 261 THR A C   1 
ATOM   274  O O   . THR A 1 261 ? 210.497 185.505 164.462 1.00 121.83 ? 261 THR A O   1 
ATOM   275  C CB  . THR A 1 261 ? 207.532 185.271 164.946 1.00 120.71 ? 261 THR A CB  1 
ATOM   276  O OG1 . THR A 1 261 ? 207.007 185.546 163.641 1.00 119.81 ? 261 THR A OG1 1 
ATOM   277  C CG2 . THR A 1 261 ? 206.382 185.147 165.934 1.00 119.45 ? 261 THR A CG2 1 
ATOM   278  N N   . ASP A 1 262 ? 209.788 187.448 163.568 1.00 121.63 ? 262 ASP A N   1 
ATOM   279  C CA  . ASP A 1 262 ? 210.937 187.543 162.677 1.00 123.03 ? 262 ASP A CA  1 
ATOM   280  C C   . ASP A 1 262 ? 212.215 187.892 163.425 1.00 123.34 ? 262 ASP A C   1 
ATOM   281  O O   . ASP A 1 262 ? 213.309 187.693 162.886 1.00 121.86 ? 262 ASP A O   1 
ATOM   282  C CB  . ASP A 1 262 ? 210.675 188.580 161.583 1.00 121.61 ? 262 ASP A CB  1 
ATOM   283  C CG  . ASP A 1 262 ? 210.195 189.905 162.139 1.00 122.52 ? 262 ASP A CG  1 
ATOM   284  O OD1 . ASP A 1 262 ? 209.910 189.971 163.352 1.00 122.61 ? 262 ASP A OD1 1 
ATOM   285  O OD2 . ASP A 1 262 ? 210.104 190.881 161.365 1.00 123.97 ? 262 ASP A OD2 1 
ATOM   286  N N   . ARG A 1 263 ? 212.106 188.404 164.647 1.00 119.18 ? 263 ARG A N   1 
ATOM   287  C CA  . ARG A 1 263 ? 213.260 188.780 165.447 1.00 117.68 ? 263 ARG A CA  1 
ATOM   288  C C   . ARG A 1 263 ? 213.353 187.878 166.670 1.00 117.08 ? 263 ARG A C   1 
ATOM   289  O O   . ARG A 1 263 ? 212.334 187.520 167.269 1.00 116.92 ? 263 ARG A O   1 
ATOM   290  C CB  . ARG A 1 263 ? 213.178 190.247 165.878 1.00 116.27 ? 263 ARG A CB  1 
ATOM   291  C CG  . ARG A 1 263 ? 212.784 191.186 164.750 1.00 117.09 ? 263 ARG A CG  1 
ATOM   292  C CD  . ARG A 1 263 ? 212.274 192.519 165.272 1.00 116.64 ? 263 ARG A CD  1 
ATOM   293  N NE  . ARG A 1 263 ? 213.377 193.405 165.631 1.00 119.78 ? 263 ARG A NE  1 
ATOM   294  C CZ  . ARG A 1 263 ? 214.305 193.841 164.787 1.00 119.41 ? 263 ARG A CZ  1 
ATOM   295  N NH1 . ARG A 1 263 ? 214.232 193.602 163.488 1.00 118.12 ? 263 ARG A NH1 1 
ATOM   296  N NH2 . ARG A 1 263 ? 215.330 194.544 165.257 1.00 118.71 ? 263 ARG A NH2 1 
ATOM   297  N N   . SER A 1 264 ? 214.580 187.513 167.033 1.00 100.19 ? 264 SER A N   1 
ATOM   298  C CA  . SER A 1 264 ? 214.796 186.620 168.162 1.00 97.96  ? 264 SER A CA  1 
ATOM   299  C C   . SER A 1 264 ? 214.545 187.362 169.469 1.00 99.31  ? 264 SER A C   1 
ATOM   300  O O   . SER A 1 264 ? 215.218 188.354 169.769 1.00 99.03  ? 264 SER A O   1 
ATOM   301  C CB  . SER A 1 264 ? 216.215 186.058 168.127 1.00 94.12  ? 264 SER A CB  1 
ATOM   302  O OG  . SER A 1 264 ? 217.173 187.086 168.306 1.00 93.02  ? 264 SER A OG  1 
ATOM   303  N N   . ILE A 1 265 ? 213.572 186.878 170.248 1.00 89.32  ? 265 ILE A N   1 
ATOM   304  C CA  . ILE A 1 265 ? 213.275 187.461 171.555 1.00 87.32  ? 265 ILE A CA  1 
ATOM   305  C C   . ILE A 1 265 ? 214.159 186.904 172.654 1.00 85.00  ? 265 ILE A C   1 
ATOM   306  O O   . ILE A 1 265 ? 214.029 187.323 173.812 1.00 88.78  ? 265 ILE A O   1 
ATOM   307  C CB  . ILE A 1 265 ? 211.802 187.231 171.943 1.00 89.94  ? 265 ILE A CB  1 
ATOM   308  C CG1 . ILE A 1 265 ? 211.548 185.742 172.186 1.00 84.03  ? 265 ILE A CG1 1 
ATOM   309  C CG2 . ILE A 1 265 ? 210.875 187.766 170.863 1.00 91.12  ? 265 ILE A CG2 1 
ATOM   310  C CD1 . ILE A 1 265 ? 210.238 185.449 172.879 1.00 85.84  ? 265 ILE A CD1 1 
ATOM   311  N N   . TRP A 1 266 ? 215.046 185.965 172.331 1.00 82.57  ? 266 TRP A N   1 
ATOM   312  C CA  . TRP A 1 266 ? 215.855 185.323 173.363 1.00 80.55  ? 266 TRP A CA  1 
ATOM   313  C C   . TRP A 1 266 ? 216.783 186.272 174.114 1.00 81.50  ? 266 TRP A C   1 
ATOM   314  O O   . TRP A 1 266 ? 216.903 186.113 175.342 1.00 89.88  ? 266 TRP A O   1 
ATOM   315  C CB  . TRP A 1 266 ? 216.638 184.155 172.753 1.00 81.61  ? 266 TRP A CB  1 
ATOM   316  C CG  . TRP A 1 266 ? 215.854 182.886 172.775 1.00 84.99  ? 266 TRP A CG  1 
ATOM   317  C CD1 . TRP A 1 266 ? 215.512 182.111 171.707 1.00 87.29  ? 266 TRP A CD1 1 
ATOM   318  C CD2 . TRP A 1 266 ? 215.289 182.253 173.928 1.00 85.25  ? 266 TRP A CD2 1 
ATOM   319  N NE1 . TRP A 1 266 ? 214.779 181.027 172.125 1.00 89.42  ? 266 TRP A NE1 1 
ATOM   320  C CE2 . TRP A 1 266 ? 214.628 181.093 173.484 1.00 86.90  ? 266 TRP A CE2 1 
ATOM   321  C CE3 . TRP A 1 266 ? 215.284 182.552 175.294 1.00 86.43  ? 266 TRP A CE3 1 
ATOM   322  C CZ2 . TRP A 1 266 ? 213.970 180.234 174.356 1.00 85.80  ? 266 TRP A CZ2 1 
ATOM   323  C CZ3 . TRP A 1 266 ? 214.629 181.699 176.156 1.00 87.25  ? 266 TRP A CZ3 1 
ATOM   324  C CH2 . TRP A 1 266 ? 213.981 180.555 175.685 1.00 88.01  ? 266 TRP A CH2 1 
ATOM   325  N N   . PRO A 1 267 ? 217.489 187.218 173.480 1.00 69.98  ? 267 PRO A N   1 
ATOM   326  C CA  . PRO A 1 267 ? 218.286 188.159 174.286 1.00 68.48  ? 267 PRO A CA  1 
ATOM   327  C C   . PRO A 1 267 ? 217.458 188.919 175.307 1.00 76.11  ? 267 PRO A C   1 
ATOM   328  O O   . PRO A 1 267 ? 217.905 189.103 176.446 1.00 77.85  ? 267 PRO A O   1 
ATOM   329  C CB  . PRO A 1 267 ? 218.892 189.092 173.230 1.00 67.72  ? 267 PRO A CB  1 
ATOM   330  C CG  . PRO A 1 267 ? 218.957 188.264 172.004 1.00 78.11  ? 267 PRO A CG  1 
ATOM   331  C CD  . PRO A 1 267 ? 217.726 187.409 172.037 1.00 77.93  ? 267 PRO A CD  1 
ATOM   332  N N   . LEU A 1 268 ? 216.246 189.339 174.939 1.00 73.24  ? 268 LEU A N   1 
ATOM   333  C CA  . LEU A 1 268 ? 215.380 190.046 175.879 1.00 66.08  ? 268 LEU A CA  1 
ATOM   334  C C   . LEU A 1 268 ? 215.020 189.159 177.064 1.00 62.17  ? 268 LEU A C   1 
ATOM   335  O O   . LEU A 1 268 ? 215.075 189.591 178.224 1.00 65.06  ? 268 LEU A O   1 
ATOM   336  C CB  . LEU A 1 268 ? 214.118 190.520 175.158 1.00 60.63  ? 268 LEU A CB  1 
ATOM   337  C CG  . LEU A 1 268 ? 213.024 191.186 175.992 1.00 62.97  ? 268 LEU A CG  1 
ATOM   338  C CD1 . LEU A 1 268 ? 213.162 192.696 175.942 1.00 66.73  ? 268 LEU A CD1 1 
ATOM   339  C CD2 . LEU A 1 268 ? 211.648 190.752 175.512 1.00 64.73  ? 268 LEU A CD2 1 
ATOM   340  N N   . ILE A 1 269 ? 214.653 187.906 176.787 1.00 52.85  ? 269 ILE A N   1 
ATOM   341  C CA  . ILE A 1 269 ? 214.287 186.980 177.853 1.00 49.33  ? 269 ILE A CA  1 
ATOM   342  C C   . ILE A 1 269 ? 215.477 186.731 178.768 1.00 47.07  ? 269 ILE A C   1 
ATOM   343  O O   . ILE A 1 269 ? 215.341 186.715 179.996 1.00 58.30  ? 269 ILE A O   1 
ATOM   344  C CB  . ILE A 1 269 ? 213.742 185.669 177.257 1.00 52.01  ? 269 ILE A CB  1 
ATOM   345  C CG1 . ILE A 1 269 ? 212.256 185.813 176.926 1.00 55.70  ? 269 ILE A CG1 1 
ATOM   346  C CG2 . ILE A 1 269 ? 213.957 184.508 178.214 1.00 50.99  ? 269 ILE A CG2 1 
ATOM   347  C CD1 . ILE A 1 269 ? 211.405 186.230 178.105 1.00 57.10  ? 269 ILE A CD1 1 
ATOM   348  N N   . ARG A 1 270 ? 216.663 186.545 178.187 1.00 61.38  ? 270 ARG A N   1 
ATOM   349  C CA  . ARG A 1 270 ? 217.846 186.281 178.998 1.00 67.58  ? 270 ARG A CA  1 
ATOM   350  C C   . ARG A 1 270 ? 218.218 187.487 179.853 1.00 69.06  ? 270 ARG A C   1 
ATOM   351  O O   . ARG A 1 270 ? 218.663 187.328 180.995 1.00 80.14  ? 270 ARG A O   1 
ATOM   352  C CB  . ARG A 1 270 ? 219.015 185.869 178.105 1.00 69.49  ? 270 ARG A CB  1 
ATOM   353  C CG  . ARG A 1 270 ? 218.872 184.479 177.505 1.00 68.10  ? 270 ARG A CG  1 
ATOM   354  C CD  . ARG A 1 270 ? 220.054 184.131 176.619 1.00 68.95  ? 270 ARG A CD  1 
ATOM   355  N NE  . ARG A 1 270 ? 219.756 183.021 175.722 1.00 74.80  ? 270 ARG A NE  1 
ATOM   356  C CZ  . ARG A 1 270 ? 219.881 183.071 174.403 1.00 80.01  ? 270 ARG A CZ  1 
ATOM   357  N NH1 . ARG A 1 270 ? 220.300 184.166 173.789 1.00 76.88  ? 270 ARG A NH1 1 
ATOM   358  N NH2 . ARG A 1 270 ? 219.578 181.996 173.681 1.00 82.28  ? 270 ARG A NH2 1 
ATOM   359  N N   . ILE A 1 271 ? 218.051 188.701 179.322 1.00 48.13  ? 271 ILE A N   1 
ATOM   360  C CA  . ILE A 1 271 ? 218.362 189.886 180.116 1.00 51.48  ? 271 ILE A CA  1 
ATOM   361  C C   . ILE A 1 271 ? 217.370 190.044 181.263 1.00 54.30  ? 271 ILE A C   1 
ATOM   362  O O   . ILE A 1 271 ? 217.763 190.318 182.403 1.00 54.47  ? 271 ILE A O   1 
ATOM   363  C CB  . ILE A 1 271 ? 218.407 191.146 179.231 1.00 57.16  ? 271 ILE A CB  1 
ATOM   364  C CG1 . ILE A 1 271 ? 219.594 191.093 178.266 1.00 62.42  ? 271 ILE A CG1 1 
ATOM   365  C CG2 . ILE A 1 271 ? 218.493 192.396 180.087 1.00 57.88  ? 271 ILE A CG2 1 
ATOM   366  C CD1 . ILE A 1 271 ? 219.345 191.803 176.950 1.00 58.07  ? 271 ILE A CD1 1 
ATOM   367  N N   . TYR A 1 272 ? 216.076 189.864 180.994 1.00 48.45  ? 272 TYR A N   1 
ATOM   368  C CA  . TYR A 1 272 ? 215.072 190.103 182.027 1.00 42.27  ? 272 TYR A CA  1 
ATOM   369  C C   . TYR A 1 272 ? 214.892 188.928 182.983 1.00 43.98  ? 272 TYR A C   1 
ATOM   370  O O   . TYR A 1 272 ? 214.229 189.088 184.018 1.00 50.65  ? 272 TYR A O   1 
ATOM   371  C CB  . TYR A 1 272 ? 213.731 190.458 181.380 1.00 45.20  ? 272 TYR A CB  1 
ATOM   372  C CG  . TYR A 1 272 ? 213.676 191.876 180.855 1.00 42.91  ? 272 TYR A CG  1 
ATOM   373  C CD1 . TYR A 1 272 ? 214.285 192.218 179.656 1.00 40.63  ? 272 TYR A CD1 1 
ATOM   374  C CD2 . TYR A 1 272 ? 213.023 192.874 181.563 1.00 48.67  ? 272 TYR A CD2 1 
ATOM   375  C CE1 . TYR A 1 272 ? 214.242 193.511 179.176 1.00 33.43  ? 272 TYR A CE1 1 
ATOM   376  C CE2 . TYR A 1 272 ? 212.974 194.170 181.090 1.00 46.06  ? 272 TYR A CE2 1 
ATOM   377  C CZ  . TYR A 1 272 ? 213.585 194.482 179.896 1.00 38.12  ? 272 TYR A CZ  1 
ATOM   378  O OH  . TYR A 1 272 ? 213.538 195.772 179.421 1.00 51.78  ? 272 TYR A OH  1 
ATOM   379  N N   . ARG A 1 273 ? 215.466 187.764 182.668 1.00 41.35  ? 273 ARG A N   1 
ATOM   380  C CA  . ARG A 1 273 ? 215.332 186.606 183.543 1.00 37.40  ? 273 ARG A CA  1 
ATOM   381  C C   . ARG A 1 273 ? 215.976 186.856 184.900 1.00 41.38  ? 273 ARG A C   1 
ATOM   382  O O   . ARG A 1 273 ? 215.426 186.466 185.936 1.00 50.20  ? 273 ARG A O   1 
ATOM   383  C CB  . ARG A 1 273 ? 215.945 185.380 182.867 1.00 35.11  ? 273 ARG A CB  1 
ATOM   384  C CG  . ARG A 1 273 ? 215.881 184.107 183.685 1.00 39.52  ? 273 ARG A CG  1 
ATOM   385  C CD  . ARG A 1 273 ? 216.393 182.920 182.886 1.00 43.73  ? 273 ARG A CD  1 
ATOM   386  N NE  . ARG A 1 273 ? 217.797 183.073 182.525 1.00 34.51  ? 273 ARG A NE  1 
ATOM   387  C CZ  . ARG A 1 273 ? 218.362 182.519 181.461 1.00 43.47  ? 273 ARG A CZ  1 
ATOM   388  N NH1 . ARG A 1 273 ? 217.669 181.764 180.625 1.00 47.78  ? 273 ARG A NH1 1 
ATOM   389  N NH2 . ARG A 1 273 ? 219.655 182.727 181.230 1.00 49.02  ? 273 ARG A NH2 1 
ATOM   390  N N   . GLY A 1 274 ? 217.145 187.499 184.915 1.00 28.02  ? 274 GLY A N   1 
ATOM   391  C CA  . GLY A 1 274 ? 217.797 187.795 186.181 1.00 41.53  ? 274 GLY A CA  1 
ATOM   392  C C   . GLY A 1 274 ? 216.975 188.718 187.059 1.00 37.41  ? 274 GLY A C   1 
ATOM   393  O O   . GLY A 1 274 ? 216.847 188.493 188.266 1.00 44.04  ? 274 GLY A O   1 
ATOM   394  N N   . GLY A 1 275 ? 216.407 189.769 186.467 1.00 28.85  ? 275 GLY A N   1 
ATOM   395  C CA  . GLY A 1 275 ? 215.539 190.651 187.229 1.00 26.29  ? 275 GLY A CA  1 
ATOM   396  C C   . GLY A 1 275 ? 214.311 189.939 187.761 1.00 27.23  ? 275 GLY A C   1 
ATOM   397  O O   . GLY A 1 275 ? 213.927 190.127 188.920 1.00 41.07  ? 275 GLY A O   1 
ATOM   398  N N   . PHE A 1 276 ? 213.683 189.104 186.928 1.00 19.85  ? 276 PHE A N   1 
ATOM   399  C CA  . PHE A 1 276 ? 212.511 188.365 187.387 1.00 15.49  ? 276 PHE A CA  1 
ATOM   400  C C   . PHE A 1 276 ? 212.865 187.430 188.535 1.00 21.22  ? 276 PHE A C   1 
ATOM   401  O O   . PHE A 1 276 ? 212.101 187.296 189.499 1.00 41.83  ? 276 PHE A O   1 
ATOM   402  C CB  . PHE A 1 276 ? 211.892 187.578 186.235 1.00 25.85  ? 276 PHE A CB  1 
ATOM   403  C CG  . PHE A 1 276 ? 210.823 186.619 186.669 1.00 18.58  ? 276 PHE A CG  1 
ATOM   404  C CD1 . PHE A 1 276 ? 209.678 187.076 187.298 1.00 20.94  ? 276 PHE A CD1 1 
ATOM   405  C CD2 . PHE A 1 276 ? 210.966 185.259 186.457 1.00 27.11  ? 276 PHE A CD2 1 
ATOM   406  C CE1 . PHE A 1 276 ? 208.693 186.197 187.701 1.00 24.09  ? 276 PHE A CE1 1 
ATOM   407  C CE2 . PHE A 1 276 ? 209.985 184.374 186.859 1.00 32.69  ? 276 PHE A CE2 1 
ATOM   408  C CZ  . PHE A 1 276 ? 208.847 184.844 187.482 1.00 23.50  ? 276 PHE A CZ  1 
ATOM   409  N N   . LEU A 1 277 ? 214.024 186.774 188.451 1.00 32.18  ? 277 LEU A N   1 
ATOM   410  C CA  . LEU A 1 277 ? 214.432 185.873 189.521 1.00 37.99  ? 277 LEU A CA  1 
ATOM   411  C C   . LEU A 1 277 ? 214.765 186.639 190.793 1.00 39.99  ? 277 LEU A C   1 
ATOM   412  O O   . LEU A 1 277 ? 214.519 186.147 191.897 1.00 34.70  ? 277 LEU A O   1 
ATOM   413  C CB  . LEU A 1 277 ? 215.616 185.024 189.070 1.00 9.51   ? 277 LEU A CB  1 
ATOM   414  C CG  . LEU A 1 277 ? 215.221 183.960 188.049 1.00 21.88  ? 277 LEU A CG  1 
ATOM   415  C CD1 . LEU A 1 277 ? 216.396 183.600 187.182 1.00 33.08  ? 277 LEU A CD1 1 
ATOM   416  C CD2 . LEU A 1 277 ? 214.668 182.732 188.739 1.00 29.55  ? 277 LEU A CD2 1 
ATOM   417  N N   . LEU A 1 278 ? 215.322 187.845 190.664 1.00 42.23  ? 278 LEU A N   1 
ATOM   418  C CA  . LEU A 1 278 ? 215.539 188.676 191.844 1.00 26.36  ? 278 LEU A CA  1 
ATOM   419  C C   . LEU A 1 278 ? 214.215 189.050 192.502 1.00 17.82  ? 278 LEU A C   1 
ATOM   420  O O   . LEU A 1 278 ? 214.093 189.022 193.734 1.00 31.46  ? 278 LEU A O   1 
ATOM   421  C CB  . LEU A 1 278 ? 216.326 189.931 191.468 1.00 33.23  ? 278 LEU A CB  1 
ATOM   422  C CG  . LEU A 1 278 ? 216.732 190.842 192.627 1.00 25.48  ? 278 LEU A CG  1 
ATOM   423  C CD1 . LEU A 1 278 ? 217.582 190.085 193.632 1.00 24.70  ? 278 LEU A CD1 1 
ATOM   424  C CD2 . LEU A 1 278 ? 217.469 192.064 192.111 1.00 31.26  ? 278 LEU A CD2 1 
ATOM   425  N N   . ILE A 1 279 ? 213.209 189.399 191.694 1.00 15.17  ? 279 ILE A N   1 
ATOM   426  C CA  . ILE A 1 279 ? 211.891 189.720 192.245 1.00 15.47  ? 279 ILE A CA  1 
ATOM   427  C C   . ILE A 1 279 ? 211.317 188.510 192.971 1.00 22.10  ? 279 ILE A C   1 
ATOM   428  O O   . ILE A 1 279 ? 210.779 188.619 194.082 1.00 50.28  ? 279 ILE A O   1 
ATOM   429  C CB  . ILE A 1 279 ? 210.935 190.202 191.137 1.00 26.54  ? 279 ILE A CB  1 
ATOM   430  C CG1 . ILE A 1 279 ? 211.541 191.350 190.330 1.00 29.19  ? 279 ILE A CG1 1 
ATOM   431  C CG2 . ILE A 1 279 ? 209.600 190.619 191.733 1.00 24.33  ? 279 ILE A CG2 1 
ATOM   432  C CD1 . ILE A 1 279 ? 212.285 192.360 191.149 1.00 29.46  ? 279 ILE A CD1 1 
ATOM   433  N N   . GLU A 1 280 ? 211.418 187.338 192.342 1.00 12.80  ? 280 GLU A N   1 
ATOM   434  C CA  . GLU A 1 280 ? 210.905 186.117 192.952 1.00 14.83  ? 280 GLU A CA  1 
ATOM   435  C C   . GLU A 1 280 ? 211.634 185.803 194.252 1.00 24.63  ? 280 GLU A C   1 
ATOM   436  O O   . GLU A 1 280 ? 211.012 185.384 195.234 1.00 26.21  ? 280 GLU A O   1 
ATOM   437  C CB  . GLU A 1 280 ? 211.028 184.955 191.970 1.00 20.71  ? 280 GLU A CB  1 
ATOM   438  C CG  . GLU A 1 280 ? 210.971 183.585 192.614 1.00 30.05  ? 280 GLU A CG  1 
ATOM   439  C CD  . GLU A 1 280 ? 210.420 182.537 191.677 1.00 42.69  ? 280 GLU A CD  1 
ATOM   440  O OE1 . GLU A 1 280 ? 210.857 182.504 190.509 1.00 42.72  ? 280 GLU A OE1 1 
ATOM   441  O OE2 . GLU A 1 280 ? 209.550 181.748 192.103 1.00 45.56  ? 280 GLU A OE2 1 
ATOM   442  N N   . PHE A 1 281 ? 212.955 185.993 194.274 1.00 26.37  ? 281 PHE A N   1 
ATOM   443  C CA  . PHE A 1 281 ? 213.719 185.745 195.489 1.00 25.10  ? 281 PHE A CA  1 
ATOM   444  C C   . PHE A 1 281 ? 213.296 186.687 196.606 1.00 37.07  ? 281 PHE A C   1 
ATOM   445  O O   . PHE A 1 281 ? 213.167 186.268 197.758 1.00 41.74  ? 281 PHE A O   1 
ATOM   446  C CB  . PHE A 1 281 ? 215.215 185.886 195.218 1.00 19.86  ? 281 PHE A CB  1 
ATOM   447  C CG  . PHE A 1 281 ? 216.071 185.627 196.423 1.00 28.46  ? 281 PHE A CG  1 
ATOM   448  C CD1 . PHE A 1 281 ? 215.862 184.505 197.208 1.00 36.20  ? 281 PHE A CD1 1 
ATOM   449  C CD2 . PHE A 1 281 ? 217.073 186.511 196.782 1.00 29.96  ? 281 PHE A CD2 1 
ATOM   450  C CE1 . PHE A 1 281 ? 216.643 184.265 198.320 1.00 27.96  ? 281 PHE A CE1 1 
ATOM   451  C CE2 . PHE A 1 281 ? 217.858 186.275 197.893 1.00 34.10  ? 281 PHE A CE2 1 
ATOM   452  C CZ  . PHE A 1 281 ? 217.642 185.152 198.663 1.00 27.43  ? 281 PHE A CZ  1 
ATOM   453  N N   . LEU A 1 282 ? 213.079 187.965 196.287 1.00 35.38  ? 282 LEU A N   1 
ATOM   454  C CA  . LEU A 1 282 ? 212.634 188.905 197.313 1.00 6.37   ? 282 LEU A CA  1 
ATOM   455  C C   . LEU A 1 282 ? 211.255 188.531 197.849 1.00 9.83   ? 282 LEU A C   1 
ATOM   456  O O   . LEU A 1 282 ? 211.009 188.601 199.060 1.00 35.74  ? 282 LEU A O   1 
ATOM   457  C CB  . LEU A 1 282 ? 212.629 190.328 196.757 1.00 6.55   ? 282 LEU A CB  1 
ATOM   458  C CG  . LEU A 1 282 ? 213.826 191.204 197.131 1.00 0.00   ? 282 LEU A CG  1 
ATOM   459  C CD1 . LEU A 1 282 ? 213.937 191.336 198.639 1.00 10.66  ? 282 LEU A CD1 1 
ATOM   460  C CD2 . LEU A 1 282 ? 215.111 190.646 196.545 1.00 21.58  ? 282 LEU A CD2 1 
ATOM   461  N N   . PHE A 1 283 ? 210.342 188.126 196.963 1.00 17.00  ? 283 PHE A N   1 
ATOM   462  C CA  . PHE A 1 283 ? 209.003 187.743 197.406 1.00 13.37  ? 283 PHE A CA  1 
ATOM   463  C C   . PHE A 1 283 ? 209.046 186.491 198.281 1.00 23.47  ? 283 PHE A C   1 
ATOM   464  O O   . PHE A 1 283 ? 208.411 186.436 199.347 1.00 37.37  ? 283 PHE A O   1 
ATOM   465  C CB  . PHE A 1 283 ? 208.107 187.537 196.183 1.00 24.81  ? 283 PHE A CB  1 
ATOM   466  C CG  . PHE A 1 283 ? 206.822 186.817 196.471 1.00 21.25  ? 283 PHE A CG  1 
ATOM   467  C CD1 . PHE A 1 283 ? 205.937 187.299 197.420 1.00 24.01  ? 283 PHE A CD1 1 
ATOM   468  C CD2 . PHE A 1 283 ? 206.487 185.669 195.774 1.00 32.55  ? 283 PHE A CD2 1 
ATOM   469  C CE1 . PHE A 1 283 ? 204.751 186.641 197.678 1.00 32.95  ? 283 PHE A CE1 1 
ATOM   470  C CE2 . PHE A 1 283 ? 205.301 185.008 196.027 1.00 30.36  ? 283 PHE A CE2 1 
ATOM   471  C CZ  . PHE A 1 283 ? 204.432 185.495 196.979 1.00 31.65  ? 283 PHE A CZ  1 
ATOM   472  N N   . LEU A 1 284 ? 209.811 185.480 197.861 1.00 21.05  ? 284 LEU A N   1 
ATOM   473  C CA  . LEU A 1 284 ? 209.934 184.270 198.666 1.00 27.68  ? 284 LEU A CA  1 
ATOM   474  C C   . LEU A 1 284 ? 210.691 184.532 199.960 1.00 30.28  ? 284 LEU A C   1 
ATOM   475  O O   . LEU A 1 284 ? 210.465 183.839 200.952 1.00 34.43  ? 284 LEU A O   1 
ATOM   476  C CB  . LEU A 1 284 ? 210.611 183.162 197.860 1.00 27.62  ? 284 LEU A CB  1 
ATOM   477  C CG  . LEU A 1 284 ? 209.887 182.725 196.586 1.00 23.33  ? 284 LEU A CG  1 
ATOM   478  C CD1 . LEU A 1 284 ? 210.736 181.749 195.794 1.00 35.47  ? 284 LEU A CD1 1 
ATOM   479  C CD2 . LEU A 1 284 ? 208.537 182.116 196.919 1.00 30.15  ? 284 LEU A CD2 1 
ATOM   480  N N   . LEU A 1 285 ? 211.571 185.534 199.985 1.00 27.00  ? 285 LEU A N   1 
ATOM   481  C CA  . LEU A 1 285 ? 212.236 185.905 201.229 1.00 24.43  ? 285 LEU A CA  1 
ATOM   482  C C   . LEU A 1 285 ? 211.282 186.612 202.181 1.00 29.21  ? 285 LEU A C   1 
ATOM   483  O O   . LEU A 1 285 ? 211.392 186.455 203.402 1.00 31.01  ? 285 LEU A O   1 
ATOM   484  C CB  . LEU A 1 285 ? 213.445 186.785 200.925 1.00 14.56  ? 285 LEU A CB  1 
ATOM   485  C CG  . LEU A 1 285 ? 214.567 186.825 201.959 1.00 19.69  ? 285 LEU A CG  1 
ATOM   486  C CD1 . LEU A 1 285 ? 214.689 185.497 202.685 1.00 28.21  ? 285 LEU A CD1 1 
ATOM   487  C CD2 . LEU A 1 285 ? 215.864 187.165 201.262 1.00 27.27  ? 285 LEU A CD2 1 
ATOM   488  N N   . GLY A 1 286 ? 210.352 187.403 201.648 1.00 29.43  ? 286 GLY A N   1 
ATOM   489  C CA  . GLY A 1 286 ? 209.283 187.923 202.485 1.00 15.40  ? 286 GLY A CA  1 
ATOM   490  C C   . GLY A 1 286 ? 208.441 186.812 203.082 1.00 19.35  ? 286 GLY A C   1 
ATOM   491  O O   . GLY A 1 286 ? 208.100 186.840 204.270 1.00 42.42  ? 286 GLY A O   1 
ATOM   492  N N   . ILE A 1 287 ? 208.106 185.809 202.267 1.00 10.73  ? 287 ILE A N   1 
ATOM   493  C CA  . ILE A 1 287 ? 207.406 184.638 202.796 1.00 11.63  ? 287 ILE A CA  1 
ATOM   494  C C   . ILE A 1 287 ? 208.261 183.940 203.850 1.00 35.80  ? 287 ILE A C   1 
ATOM   495  O O   . ILE A 1 287 ? 207.747 183.437 204.858 1.00 39.96  ? 287 ILE A O   1 
ATOM   496  C CB  . ILE A 1 287 ? 207.017 183.678 201.657 1.00 20.24  ? 287 ILE A CB  1 
ATOM   497  C CG1 . ILE A 1 287 ? 206.163 184.397 200.614 1.00 28.82  ? 287 ILE A CG1 1 
ATOM   498  C CG2 . ILE A 1 287 ? 206.263 182.479 202.207 1.00 24.66  ? 287 ILE A CG2 1 
ATOM   499  C CD1 . ILE A 1 287 ? 205.603 183.474 199.557 1.00 24.82  ? 287 ILE A CD1 1 
ATOM   500  N N   . ASN A 1 288 ? 209.577 183.895 203.626 1.00 41.06  ? 288 ASN A N   1 
ATOM   501  C CA  . ASN A 1 288 ? 210.503 183.322 204.598 1.00 30.12  ? 288 ASN A CA  1 
ATOM   502  C C   . ASN A 1 288 ? 210.391 184.033 205.937 1.00 40.54  ? 288 ASN A C   1 
ATOM   503  O O   . ASN A 1 288 ? 210.286 183.394 206.988 1.00 50.16  ? 288 ASN A O   1 
ATOM   504  C CB  . ASN A 1 288 ? 211.938 183.432 204.077 1.00 29.53  ? 288 ASN A CB  1 
ATOM   505  C CG  . ASN A 1 288 ? 212.333 182.280 203.188 1.00 37.94  ? 288 ASN A CG  1 
ATOM   506  O OD1 . ASN A 1 288 ? 211.599 181.313 203.052 1.00 33.43  ? 288 ASN A OD1 1 
ATOM   507  N ND2 . ASN A 1 288 ? 213.500 182.383 202.569 1.00 49.81  ? 288 ASN A ND2 1 
ATOM   508  N N   . THR A 1 289 ? 210.435 185.365 205.910 1.00 35.34  ? 289 THR A N   1 
ATOM   509  C CA  . THR A 1 289 ? 210.366 186.139 207.144 1.00 21.82  ? 289 THR A CA  1 
ATOM   510  C C   . THR A 1 289 ? 209.031 185.930 207.848 1.00 19.99  ? 289 THR A C   1 
ATOM   511  O O   . THR A 1 289 ? 208.986 185.784 209.076 1.00 30.37  ? 289 THR A O   1 
ATOM   512  C CB  . THR A 1 289 ? 210.596 187.621 206.848 1.00 27.85  ? 289 THR A CB  1 
ATOM   513  O OG1 . THR A 1 289 ? 211.947 187.816 206.413 1.00 31.73  ? 289 THR A OG1 1 
ATOM   514  C CG2 . THR A 1 289 ? 210.351 188.460 208.091 1.00 28.33  ? 289 THR A CG2 1 
ATOM   515  N N   . TYR A 1 290 ? 207.934 185.903 207.086 1.00 35.39  ? 290 TYR A N   1 
ATOM   516  C CA  . TYR A 1 290 ? 206.627 185.665 207.695 1.00 36.71  ? 290 TYR A CA  1 
ATOM   517  C C   . TYR A 1 290 ? 206.576 184.300 208.372 1.00 30.75  ? 290 TYR A C   1 
ATOM   518  O O   . TYR A 1 290 ? 206.114 184.173 209.515 1.00 52.20  ? 290 TYR A O   1 
ATOM   519  C CB  . TYR A 1 290 ? 205.523 185.780 206.644 1.00 45.27  ? 290 TYR A CB  1 
ATOM   520  C CG  . TYR A 1 290 ? 204.257 185.037 207.014 1.00 45.51  ? 290 TYR A CG  1 
ATOM   521  C CD1 . TYR A 1 290 ? 203.349 185.580 207.912 1.00 43.92  ? 290 TYR A CD1 1 
ATOM   522  C CD2 . TYR A 1 290 ? 203.971 183.794 206.465 1.00 51.22  ? 290 TYR A CD2 1 
ATOM   523  C CE1 . TYR A 1 290 ? 202.193 184.905 208.254 1.00 43.82  ? 290 TYR A CE1 1 
ATOM   524  C CE2 . TYR A 1 290 ? 202.817 183.112 206.803 1.00 44.46  ? 290 TYR A CE2 1 
ATOM   525  C CZ  . TYR A 1 290 ? 201.932 183.673 207.697 1.00 42.42  ? 290 TYR A CZ  1 
ATOM   526  O OH  . TYR A 1 290 ? 200.782 183.000 208.035 1.00 46.61  ? 290 TYR A OH  1 
ATOM   527  N N   . GLY A 1 291 ? 207.044 183.263 207.674 1.00 25.26  ? 291 GLY A N   1 
ATOM   528  C CA  . GLY A 1 291 ? 207.033 181.930 208.250 1.00 41.83  ? 291 GLY A CA  1 
ATOM   529  C C   . GLY A 1 291 ? 207.919 181.820 209.474 1.00 43.40  ? 291 GLY A C   1 
ATOM   530  O O   . GLY A 1 291 ? 207.564 181.160 210.452 1.00 40.63  ? 291 GLY A O   1 
ATOM   531  N N   . TRP A 1 292 ? 209.086 182.467 209.437 1.00 47.00  ? 292 TRP A N   1 
ATOM   532  C CA  . TRP A 1 292 ? 209.979 182.448 210.589 1.00 38.65  ? 292 TRP A CA  1 
ATOM   533  C C   . TRP A 1 292 ? 209.341 183.134 211.788 1.00 45.47  ? 292 TRP A C   1 
ATOM   534  O O   . TRP A 1 292 ? 209.407 182.630 212.915 1.00 48.85  ? 292 TRP A O   1 
ATOM   535  C CB  . TRP A 1 292 ? 211.310 183.112 210.237 1.00 31.54  ? 292 TRP A CB  1 
ATOM   536  C CG  . TRP A 1 292 ? 212.057 182.419 209.147 1.00 30.23  ? 292 TRP A CG  1 
ATOM   537  C CD1 . TRP A 1 292 ? 211.857 181.147 208.698 1.00 35.42  ? 292 TRP A CD1 1 
ATOM   538  C CD2 . TRP A 1 292 ? 213.117 182.963 208.355 1.00 36.74  ? 292 TRP A CD2 1 
ATOM   539  N NE1 . TRP A 1 292 ? 212.732 180.863 207.679 1.00 41.80  ? 292 TRP A NE1 1 
ATOM   540  C CE2 . TRP A 1 292 ? 213.516 181.963 207.449 1.00 41.70  ? 292 TRP A CE2 1 
ATOM   541  C CE3 . TRP A 1 292 ? 213.770 184.198 208.326 1.00 43.80  ? 292 TRP A CE3 1 
ATOM   542  C CZ2 . TRP A 1 292 ? 214.537 182.160 206.524 1.00 49.24  ? 292 TRP A CZ2 1 
ATOM   543  C CZ3 . TRP A 1 292 ? 214.784 184.391 207.408 1.00 41.05  ? 292 TRP A CZ3 1 
ATOM   544  C CH2 . TRP A 1 292 ? 215.158 183.378 206.521 1.00 50.33  ? 292 TRP A CH2 1 
ATOM   545  N N   . ARG A 1 293 ? 208.720 184.294 211.565 1.00 50.45  ? 293 ARG A N   1 
ATOM   546  C CA  . ARG A 1 293 ? 208.108 185.021 212.671 1.00 47.26  ? 293 ARG A CA  1 
ATOM   547  C C   . ARG A 1 293 ? 206.944 184.244 213.273 1.00 48.33  ? 293 ARG A C   1 
ATOM   548  O O   . ARG A 1 293 ? 206.812 184.167 214.500 1.00 55.42  ? 293 ARG A O   1 
ATOM   549  C CB  . ARG A 1 293 ? 207.649 186.400 212.203 1.00 50.05  ? 293 ARG A CB  1 
ATOM   550  C CG  . ARG A 1 293 ? 207.408 187.377 213.338 1.00 53.60  ? 293 ARG A CG  1 
ATOM   551  C CD  . ARG A 1 293 ? 208.714 187.990 213.818 1.00 55.81  ? 293 ARG A CD  1 
ATOM   552  N NE  . ARG A 1 293 ? 209.375 188.766 212.776 1.00 56.08  ? 293 ARG A NE  1 
ATOM   553  C CZ  . ARG A 1 293 ? 208.955 189.943 212.333 1.00 61.20  ? 293 ARG A CZ  1 
ATOM   554  N NH1 . ARG A 1 293 ? 207.876 190.526 212.830 1.00 59.09  ? 293 ARG A NH1 1 
ATOM   555  N NH2 . ARG A 1 293 ? 209.638 190.554 211.369 1.00 61.84  ? 293 ARG A NH2 1 
ATOM   556  N N   . GLN A 1 294 ? 206.091 183.657 212.431 1.00 52.73  ? 294 GLN A N   1 
ATOM   557  C CA  . GLN A 1 294 ? 204.913 182.978 212.963 1.00 51.50  ? 294 GLN A CA  1 
ATOM   558  C C   . GLN A 1 294 ? 205.235 181.609 213.554 1.00 57.03  ? 294 GLN A C   1 
ATOM   559  O O   . GLN A 1 294 ? 204.594 181.199 214.527 1.00 64.80  ? 294 GLN A O   1 
ATOM   560  C CB  . GLN A 1 294 ? 203.842 182.847 211.881 1.00 56.03  ? 294 GLN A CB  1 
ATOM   561  C CG  . GLN A 1 294 ? 203.268 184.179 211.432 1.00 58.40  ? 294 GLN A CG  1 
ATOM   562  C CD  . GLN A 1 294 ? 202.443 184.856 212.513 1.00 60.77  ? 294 GLN A CD  1 
ATOM   563  O OE1 . GLN A 1 294 ? 201.957 184.207 213.440 1.00 62.11  ? 294 GLN A OE1 1 
ATOM   564  N NE2 . GLN A 1 294 ? 202.281 186.169 212.397 1.00 57.99  ? 294 GLN A NE2 1 
ATOM   565  N N   . ALA A 1 295 ? 206.206 180.888 212.987 1.00 56.87  ? 295 ALA A N   1 
ATOM   566  C CA  . ALA A 1 295 ? 206.511 179.548 213.481 1.00 61.63  ? 295 ALA A CA  1 
ATOM   567  C C   . ALA A 1 295 ? 207.103 179.589 214.885 1.00 56.30  ? 295 ALA A C   1 
ATOM   568  O O   . ALA A 1 295 ? 206.723 178.788 215.747 1.00 54.77  ? 295 ALA A O   1 
ATOM   569  C CB  . ALA A 1 295 ? 207.462 178.840 212.518 1.00 64.84  ? 295 ALA A CB  1 
ATOM   570  N N   . GLY A 1 296 ? 208.030 180.509 215.134 1.00 54.32  ? 296 GLY A N   1 
ATOM   571  C CA  . GLY A 1 296 ? 208.651 180.609 216.439 1.00 55.89  ? 296 GLY A CA  1 
ATOM   572  C C   . GLY A 1 296 ? 210.160 180.723 216.385 1.00 59.81  ? 296 GLY A C   1 
ATOM   573  O O   . GLY A 1 296 ? 210.794 181.112 217.370 1.00 64.11  ? 296 GLY A O   1 
ATOM   574  N N   . VAL A 1 297 ? 210.748 180.381 215.236 1.00 53.94  ? 297 VAL A N   1 
ATOM   575  C CA  . VAL A 1 297 ? 212.192 180.498 215.074 1.00 54.87  ? 297 VAL A CA  1 
ATOM   576  C C   . VAL A 1 297 ? 212.608 181.958 215.175 1.00 52.16  ? 297 VAL A C   1 
ATOM   577  O O   . VAL A 1 297 ? 212.043 182.837 214.511 1.00 58.21  ? 297 VAL A O   1 
ATOM   578  C CB  . VAL A 1 297 ? 212.631 179.858 213.749 1.00 44.78  ? 297 VAL A CB  1 
ATOM   579  C CG1 . VAL A 1 297 ? 211.731 180.295 212.632 1.00 52.48  ? 297 VAL A CG1 1 
ATOM   580  C CG2 . VAL A 1 297 ? 214.055 180.258 213.417 1.00 42.51  ? 297 VAL A CG2 1 
ATOM   581  N N   . ASN A 1 298 ? 213.600 182.222 216.025 1.00 55.94  ? 298 ASN A N   1 
ATOM   582  C CA  . ASN A 1 298 ? 214.076 183.576 216.304 1.00 49.25  ? 298 ASN A CA  1 
ATOM   583  C C   . ASN A 1 298 ? 215.129 183.926 215.261 1.00 45.39  ? 298 ASN A C   1 
ATOM   584  O O   . ASN A 1 298 ? 216.332 183.806 215.495 1.00 54.49  ? 298 ASN A O   1 
ATOM   585  C CB  . ASN A 1 298 ? 214.624 183.660 217.724 1.00 56.11  ? 298 ASN A CB  1 
ATOM   586  C CG  . ASN A 1 298 ? 214.888 185.085 218.170 1.00 62.06  ? 298 ASN A CG  1 
ATOM   587  O OD1 . ASN A 1 298 ? 214.955 186.002 217.356 1.00 63.41  ? 298 ASN A OD1 1 
ATOM   588  N ND2 . ASN A 1 298 ? 215.040 185.275 219.476 1.00 58.21  ? 298 ASN A ND2 1 
ATOM   589  N N   . HIS A 1 299 ? 214.667 184.367 214.089 1.00 46.98  ? 299 HIS A N   1 
ATOM   590  C CA  . HIS A 1 299 ? 215.583 184.621 212.981 1.00 53.60  ? 299 HIS A CA  1 
ATOM   591  C C   . HIS A 1 299 ? 216.438 185.861 213.225 1.00 54.10  ? 299 HIS A C   1 
ATOM   592  O O   . HIS A 1 299 ? 217.604 185.903 212.815 1.00 52.37  ? 299 HIS A O   1 
ATOM   593  C CB  . HIS A 1 299 ? 214.802 184.755 211.674 1.00 51.70  ? 299 HIS A CB  1 
ATOM   594  C CG  . HIS A 1 299 ? 214.083 186.059 211.529 1.00 47.20  ? 299 HIS A CG  1 
ATOM   595  N ND1 . HIS A 1 299 ? 214.482 187.034 210.640 1.00 49.71  ? 299 HIS A ND1 1 
ATOM   596  C CD2 . HIS A 1 299 ? 212.988 186.549 212.157 1.00 50.79  ? 299 HIS A CD2 1 
ATOM   597  C CE1 . HIS A 1 299 ? 213.666 188.069 210.729 1.00 57.38  ? 299 HIS A CE1 1 
ATOM   598  N NE2 . HIS A 1 299 ? 212.751 187.800 211.642 1.00 57.09  ? 299 HIS A NE2 1 
ATOM   599  N N   . VAL A 1 300 ? 215.880 186.883 213.880 1.00 60.09  ? 300 VAL A N   1 
ATOM   600  C CA  . VAL A 1 300 ? 216.638 188.112 214.105 1.00 57.64  ? 300 VAL A CA  1 
ATOM   601  C C   . VAL A 1 300 ? 217.827 187.851 215.020 1.00 61.32  ? 300 VAL A C   1 
ATOM   602  O O   . VAL A 1 300 ? 218.914 188.406 214.813 1.00 63.90  ? 300 VAL A O   1 
ATOM   603  C CB  . VAL A 1 300 ? 215.718 189.223 214.655 1.00 57.54  ? 300 VAL A CB  1 
ATOM   604  C CG1 . VAL A 1 300 ? 214.885 188.716 215.818 1.00 55.06  ? 300 VAL A CG1 1 
ATOM   605  C CG2 . VAL A 1 300 ? 216.530 190.443 215.066 1.00 60.47  ? 300 VAL A CG2 1 
ATOM   606  N N   . LEU A 1 301 ? 217.653 187.001 216.033 1.00 59.57  ? 301 LEU A N   1 
ATOM   607  C CA  . LEU A 1 301 ? 218.780 186.603 216.870 1.00 56.08  ? 301 LEU A CA  1 
ATOM   608  C C   . LEU A 1 301 ? 219.811 185.824 216.062 1.00 47.56  ? 301 LEU A C   1 
ATOM   609  O O   . LEU A 1 301 ? 221.021 186.029 216.216 1.00 49.40  ? 301 LEU A O   1 
ATOM   610  C CB  . LEU A 1 301 ? 218.284 185.774 218.055 1.00 50.93  ? 301 LEU A CB  1 
ATOM   611  C CG  . LEU A 1 301 ? 219.309 184.906 218.790 1.00 51.65  ? 301 LEU A CG  1 
ATOM   612  C CD1 . LEU A 1 301 ? 220.371 185.765 219.463 1.00 54.26  ? 301 LEU A CD1 1 
ATOM   613  C CD2 . LEU A 1 301 ? 218.621 184.002 219.801 1.00 55.63  ? 301 LEU A CD2 1 
ATOM   614  N N   . ILE A 1 302 ? 219.348 184.923 215.194 1.00 36.05  ? 302 ILE A N   1 
ATOM   615  C CA  . ILE A 1 302 ? 220.263 184.102 214.407 1.00 38.35  ? 302 ILE A CA  1 
ATOM   616  C C   . ILE A 1 302 ? 221.040 184.964 213.419 1.00 40.30  ? 302 ILE A C   1 
ATOM   617  O O   . ILE A 1 302 ? 222.268 184.865 213.315 1.00 43.43  ? 302 ILE A O   1 
ATOM   618  C CB  . ILE A 1 302 ? 219.489 182.979 213.693 1.00 36.76  ? 302 ILE A CB  1 
ATOM   619  C CG1 . ILE A 1 302 ? 218.939 181.981 214.711 1.00 37.96  ? 302 ILE A CG1 1 
ATOM   620  C CG2 . ILE A 1 302 ? 220.385 182.261 212.710 1.00 43.05  ? 302 ILE A CG2 1 
ATOM   621  C CD1 . ILE A 1 302 ? 217.917 181.031 214.133 1.00 39.36  ? 302 ILE A CD1 1 
ATOM   622  N N   . PHE A 1 303 ? 220.338 185.827 212.683 1.00 46.08  ? 303 PHE A N   1 
ATOM   623  C CA  . PHE A 1 303 ? 220.988 186.726 211.736 1.00 49.05  ? 303 PHE A CA  1 
ATOM   624  C C   . PHE A 1 303 ? 221.755 187.854 212.415 1.00 53.78  ? 303 PHE A C   1 
ATOM   625  O O   . PHE A 1 303 ? 222.479 188.581 211.726 1.00 51.63  ? 303 PHE A O   1 
ATOM   626  C CB  . PHE A 1 303 ? 219.959 187.323 210.777 1.00 52.27  ? 303 PHE A CB  1 
ATOM   627  C CG  . PHE A 1 303 ? 219.606 186.432 209.624 1.00 43.46  ? 303 PHE A CG  1 
ATOM   628  C CD1 . PHE A 1 303 ? 218.888 185.267 209.820 1.00 46.83  ? 303 PHE A CD1 1 
ATOM   629  C CD2 . PHE A 1 303 ? 219.989 186.767 208.338 1.00 40.61  ? 303 PHE A CD2 1 
ATOM   630  C CE1 . PHE A 1 303 ? 218.562 184.454 208.755 1.00 47.67  ? 303 PHE A CE1 1 
ATOM   631  C CE2 . PHE A 1 303 ? 219.666 185.957 207.271 1.00 42.52  ? 303 PHE A CE2 1 
ATOM   632  C CZ  . PHE A 1 303 ? 218.952 184.798 207.480 1.00 46.40  ? 303 PHE A CZ  1 
ATOM   633  N N   . GLU A 1 304 ? 221.602 188.022 213.730 1.00 62.51  ? 304 GLU A N   1 
ATOM   634  C CA  . GLU A 1 304 ? 222.277 189.079 214.488 1.00 62.65  ? 304 GLU A CA  1 
ATOM   635  C C   . GLU A 1 304 ? 221.872 190.469 214.000 1.00 63.82  ? 304 GLU A C   1 
ATOM   636  O O   . GLU A 1 304 ? 222.700 191.376 213.893 1.00 66.74  ? 304 GLU A O   1 
ATOM   637  C CB  . GLU A 1 304 ? 223.799 188.913 214.447 1.00 59.29  ? 304 GLU A CB  1 
ATOM   638  C CG  . GLU A 1 304 ? 224.299 187.581 214.980 1.00 59.20  ? 304 GLU A CG  1 
ATOM   639  C CD  . GLU A 1 304 ? 225.518 187.078 214.232 1.00 63.15  ? 304 GLU A CD  1 
ATOM   640  O OE1 . GLU A 1 304 ? 226.195 187.898 213.576 1.00 63.64  ? 304 GLU A OE1 1 
ATOM   641  O OE2 . GLU A 1 304 ? 225.799 185.864 214.299 1.00 63.78  ? 304 GLU A OE2 1 
ATOM   642  N N   . LEU A 1 305 ? 220.589 190.639 213.697 1.00 61.65  ? 305 LEU A N   1 
ATOM   643  C CA  . LEU A 1 305 ? 220.044 191.948 213.376 1.00 62.77  ? 305 LEU A CA  1 
ATOM   644  C C   . LEU A 1 305 ? 219.702 192.712 214.652 1.00 64.83  ? 305 LEU A C   1 
ATOM   645  O O   . LEU A 1 305 ? 219.711 192.170 215.759 1.00 61.21  ? 305 LEU A O   1 
ATOM   646  C CB  . LEU A 1 305 ? 218.802 191.823 212.494 1.00 62.26  ? 305 LEU A CB  1 
ATOM   647  C CG  . LEU A 1 305 ? 218.712 190.637 211.539 1.00 57.47  ? 305 LEU A CG  1 
ATOM   648  C CD1 . LEU A 1 305 ? 217.318 190.538 210.956 1.00 53.87  ? 305 LEU A CD1 1 
ATOM   649  C CD2 . LEU A 1 305 ? 219.731 190.817 210.431 1.00 64.53  ? 305 LEU A CD2 1 
ATOM   650  N N   . ASN A 1 306 ? 219.398 193.993 214.483 1.00 83.50  ? 306 ASN A N   1 
ATOM   651  C CA  . ASN A 1 306 ? 218.941 194.807 215.599 1.00 86.50  ? 306 ASN A CA  1 
ATOM   652  C C   . ASN A 1 306 ? 217.504 194.431 215.938 1.00 86.57  ? 306 ASN A C   1 
ATOM   653  O O   . ASN A 1 306 ? 216.632 194.516 215.066 1.00 84.25  ? 306 ASN A O   1 
ATOM   654  C CB  . ASN A 1 306 ? 219.033 196.288 215.256 1.00 85.35  ? 306 ASN A CB  1 
ATOM   655  C CG  . ASN A 1 306 ? 219.490 197.130 216.429 1.00 85.69  ? 306 ASN A CG  1 
ATOM   656  O OD1 . ASN A 1 306 ? 219.665 196.627 217.539 1.00 86.12  ? 306 ASN A OD1 1 
ATOM   657  N ND2 . ASN A 1 306 ? 219.689 198.421 216.189 1.00 85.35  ? 306 ASN A ND2 1 
ATOM   658  N N   . PRO A 1 307 ? 217.216 194.003 217.170 1.00 87.38  ? 307 PRO A N   1 
ATOM   659  C CA  . PRO A 1 307 ? 215.845 193.581 217.500 1.00 86.94  ? 307 PRO A CA  1 
ATOM   660  C C   . PRO A 1 307 ? 214.809 194.679 217.343 1.00 92.81  ? 307 PRO A C   1 
ATOM   661  O O   . PRO A 1 307 ? 213.634 194.371 217.106 1.00 96.26  ? 307 PRO A O   1 
ATOM   662  C CB  . PRO A 1 307 ? 215.961 193.128 218.962 1.00 87.80  ? 307 PRO A CB  1 
ATOM   663  C CG  . PRO A 1 307 ? 217.413 192.810 219.148 1.00 89.42  ? 307 PRO A CG  1 
ATOM   664  C CD  . PRO A 1 307 ? 218.141 193.805 218.297 1.00 88.34  ? 307 PRO A CD  1 
ATOM   665  N N   . ARG A 1 308 ? 215.199 195.946 217.463 1.00 98.15  ? 308 ARG A N   1 
ATOM   666  C CA  . ARG A 1 308 ? 214.265 197.060 217.391 1.00 98.34  ? 308 ARG A CA  1 
ATOM   667  C C   . ARG A 1 308 ? 214.152 197.658 215.995 1.00 95.87  ? 308 ARG A C   1 
ATOM   668  O O   . ARG A 1 308 ? 213.388 198.610 215.806 1.00 97.64  ? 308 ARG A O   1 
ATOM   669  C CB  . ARG A 1 308 ? 214.668 198.155 218.386 1.00 99.61  ? 308 ARG A CB  1 
ATOM   670  C CG  . ARG A 1 308 ? 215.474 197.663 219.582 1.00 97.29  ? 308 ARG A CG  1 
ATOM   671  C CD  . ARG A 1 308 ? 214.641 196.774 220.497 1.00 96.52  ? 308 ARG A CD  1 
ATOM   672  N NE  . ARG A 1 308 ? 213.588 197.519 221.177 1.00 97.78  ? 308 ARG A NE  1 
ATOM   673  C CZ  . ARG A 1 308 ? 212.470 196.978 221.641 1.00 99.57  ? 308 ARG A CZ  1 
ATOM   674  N NH1 . ARG A 1 308 ? 212.224 195.685 221.515 1.00 97.00  ? 308 ARG A NH1 1 
ATOM   675  N NH2 . ARG A 1 308 ? 211.576 197.755 222.247 1.00 99.91  ? 308 ARG A NH2 1 
ATOM   676  N N   . SER A 1 309 ? 214.888 197.130 215.013 1.00 83.48  ? 309 SER A N   1 
ATOM   677  C CA  . SER A 1 309 ? 214.867 197.676 213.662 1.00 86.64  ? 309 SER A CA  1 
ATOM   678  C C   . SER A 1 309 ? 214.769 196.601 212.586 1.00 89.49  ? 309 SER A C   1 
ATOM   679  O O   . SER A 1 309 ? 215.034 196.892 211.414 1.00 91.19  ? 309 SER A O   1 
ATOM   680  C CB  . SER A 1 309 ? 216.108 198.542 213.414 1.00 89.42  ? 309 SER A CB  1 
ATOM   681  O OG  . SER A 1 309 ? 215.884 199.464 212.363 1.00 91.56  ? 309 SER A OG  1 
ATOM   682  N N   . ASN A 1 310 ? 214.401 195.374 212.946 1.00 76.19  ? 310 ASN A N   1 
ATOM   683  C CA  . ASN A 1 310 ? 214.287 194.312 211.957 1.00 76.02  ? 310 ASN A CA  1 
ATOM   684  C C   . ASN A 1 310 ? 213.129 194.589 211.003 1.00 79.15  ? 310 ASN A C   1 
ATOM   685  O O   . ASN A 1 310 ? 212.119 195.195 211.372 1.00 77.27  ? 310 ASN A O   1 
ATOM   686  C CB  . ASN A 1 310 ? 214.093 192.961 212.646 1.00 67.32  ? 310 ASN A CB  1 
ATOM   687  C CG  . ASN A 1 310 ? 212.680 192.761 213.153 1.00 64.59  ? 310 ASN A CG  1 
ATOM   688  O OD1 . ASN A 1 310 ? 212.155 193.585 213.901 1.00 68.26  ? 310 ASN A OD1 1 
ATOM   689  N ND2 . ASN A 1 310 ? 212.057 191.661 212.749 1.00 63.13  ? 310 ASN A ND2 1 
ATOM   690  N N   . LEU A 1 311 ? 213.287 194.141 209.760 1.00 71.80  ? 311 LEU A N   1 
ATOM   691  C CA  . LEU A 1 311 ? 212.277 194.334 208.728 1.00 65.03  ? 311 LEU A CA  1 
ATOM   692  C C   . LEU A 1 311 ? 211.264 193.198 208.787 1.00 68.90  ? 311 LEU A C   1 
ATOM   693  O O   . LEU A 1 311 ? 211.638 192.022 208.728 1.00 67.58  ? 311 LEU A O   1 
ATOM   694  C CB  . LEU A 1 311 ? 212.917 194.399 207.342 1.00 59.02  ? 311 LEU A CB  1 
ATOM   695  C CG  . LEU A 1 311 ? 213.745 195.633 206.985 1.00 62.16  ? 311 LEU A CG  1 
ATOM   696  C CD1 . LEU A 1 311 ? 213.717 195.858 205.482 1.00 60.63  ? 311 LEU A CD1 1 
ATOM   697  C CD2 . LEU A 1 311 ? 213.240 196.863 207.722 1.00 66.55  ? 311 LEU A CD2 1 
ATOM   698  N N   . SER A 1 312 ? 209.987 193.551 208.903 1.00 61.39  ? 312 SER A N   1 
ATOM   699  C CA  . SER A 1 312 ? 208.935 192.553 208.836 1.00 54.80  ? 312 SER A CA  1 
ATOM   700  C C   . SER A 1 312 ? 208.777 192.058 207.400 1.00 50.99  ? 312 SER A C   1 
ATOM   701  O O   . SER A 1 312 ? 209.350 192.606 206.455 1.00 51.39  ? 312 SER A O   1 
ATOM   702  C CB  . SER A 1 312 ? 207.616 193.127 209.352 1.00 53.54  ? 312 SER A CB  1 
ATOM   703  O OG  . SER A 1 312 ? 207.834 194.010 210.438 1.00 59.11  ? 312 SER A OG  1 
ATOM   704  N N   . HIS A 1 313 ? 207.984 190.997 207.243 1.00 38.10  ? 313 HIS A N   1 
ATOM   705  C CA  . HIS A 1 313 ? 207.722 190.468 205.911 1.00 41.57  ? 313 HIS A CA  1 
ATOM   706  C C   . HIS A 1 313 ? 206.979 191.464 205.033 1.00 43.15  ? 313 HIS A C   1 
ATOM   707  O O   . HIS A 1 313 ? 207.072 191.379 203.804 1.00 47.32  ? 313 HIS A O   1 
ATOM   708  C CB  . HIS A 1 313 ? 206.929 189.164 206.002 1.00 38.62  ? 313 HIS A CB  1 
ATOM   709  C CG  . HIS A 1 313 ? 205.709 189.251 206.863 1.00 40.92  ? 313 HIS A CG  1 
ATOM   710  N ND1 . HIS A 1 313 ? 205.772 189.380 208.234 1.00 52.24  ? 313 HIS A ND1 1 
ATOM   711  C CD2 . HIS A 1 313 ? 204.393 189.221 206.548 1.00 44.57  ? 313 HIS A CD2 1 
ATOM   712  C CE1 . HIS A 1 313 ? 204.547 189.429 208.726 1.00 55.54  ? 313 HIS A CE1 1 
ATOM   713  N NE2 . HIS A 1 313 ? 203.691 189.335 207.724 1.00 54.33  ? 313 HIS A NE2 1 
ATOM   714  N N   . GLN A 1 314 ? 206.251 192.407 205.636 1.00 52.79  ? 314 GLN A N   1 
ATOM   715  C CA  . GLN A 1 314 ? 205.550 193.417 204.851 1.00 50.03  ? 314 GLN A CA  1 
ATOM   716  C C   . GLN A 1 314 ? 206.527 194.295 204.081 1.00 49.74  ? 314 GLN A C   1 
ATOM   717  O O   . GLN A 1 314 ? 206.280 194.636 202.921 1.00 57.10  ? 314 GLN A O   1 
ATOM   718  C CB  . GLN A 1 314 ? 204.662 194.264 205.762 1.00 50.40  ? 314 GLN A CB  1 
ATOM   719  C CG  . GLN A 1 314 ? 203.915 193.463 206.816 1.00 55.09  ? 314 GLN A CG  1 
ATOM   720  C CD  . GLN A 1 314 ? 202.605 192.890 206.308 1.00 54.36  ? 314 GLN A CD  1 
ATOM   721  O OE1 . GLN A 1 314 ? 201.885 192.218 207.045 1.00 60.38  ? 314 GLN A OE1 1 
ATOM   722  N NE2 . GLN A 1 314 ? 202.287 193.160 205.048 1.00 40.60  ? 314 GLN A NE2 1 
ATOM   723  N N   . HIS A 1 315 ? 207.645 194.674 204.707 1.00 39.46  ? 315 HIS A N   1 
ATOM   724  C CA  . HIS A 1 315 ? 208.635 195.494 204.014 1.00 33.49  ? 315 HIS A CA  1 
ATOM   725  C C   . HIS A 1 315 ? 209.258 194.743 202.842 1.00 42.78  ? 315 HIS A C   1 
ATOM   726  O O   . HIS A 1 315 ? 209.481 195.322 201.770 1.00 49.49  ? 315 HIS A O   1 
ATOM   727  C CB  . HIS A 1 315 ? 209.717 195.954 204.990 1.00 36.23  ? 315 HIS A CB  1 
ATOM   728  C CG  . HIS A 1 315 ? 209.209 196.833 206.091 1.00 52.62  ? 315 HIS A CG  1 
ATOM   729  N ND1 . HIS A 1 315 ? 208.128 196.497 206.877 1.00 52.92  ? 315 HIS A ND1 1 
ATOM   730  C CD2 . HIS A 1 315 ? 209.637 198.038 206.537 1.00 53.81  ? 315 HIS A CD2 1 
ATOM   731  C CE1 . HIS A 1 315 ? 207.912 197.456 207.759 1.00 51.58  ? 315 HIS A CE1 1 
ATOM   732  N NE2 . HIS A 1 315 ? 208.814 198.403 207.574 1.00 51.96  ? 315 HIS A NE2 1 
ATOM   733  N N   . LEU A 1 316 ? 209.559 193.456 203.034 1.00 40.08  ? 316 LEU A N   1 
ATOM   734  C CA  . LEU A 1 316 ? 210.106 192.655 201.944 1.00 34.92  ? 316 LEU A CA  1 
ATOM   735  C C   . LEU A 1 316 ? 209.100 192.510 200.811 1.00 25.58  ? 316 LEU A C   1 
ATOM   736  O O   . LEU A 1 316 ? 209.465 192.606 199.634 1.00 30.05  ? 316 LEU A O   1 
ATOM   737  C CB  . LEU A 1 316 ? 210.543 191.287 202.464 1.00 24.08  ? 316 LEU A CB  1 
ATOM   738  C CG  . LEU A 1 316 ? 211.942 191.219 203.078 1.00 20.89  ? 316 LEU A CG  1 
ATOM   739  C CD1 . LEU A 1 316 ? 212.393 189.778 203.230 1.00 25.38  ? 316 LEU A CD1 1 
ATOM   740  C CD2 . LEU A 1 316 ? 212.939 192.008 202.243 1.00 19.83  ? 316 LEU A CD2 1 
ATOM   741  N N   . PHE A 1 317 ? 207.826 192.286 201.145 1.00 21.47  ? 317 PHE A N   1 
ATOM   742  C CA  . PHE A 1 317 ? 206.795 192.245 200.114 1.00 23.20  ? 317 PHE A CA  1 
ATOM   743  C C   . PHE A 1 317 ? 206.703 193.577 199.382 1.00 33.25  ? 317 PHE A C   1 
ATOM   744  O O   . PHE A 1 317 ? 206.524 193.611 198.161 1.00 20.56  ? 317 PHE A O   1 
ATOM   745  C CB  . PHE A 1 317 ? 205.444 191.881 200.728 1.00 31.98  ? 317 PHE A CB  1 
ATOM   746  C CG  . PHE A 1 317 ? 205.328 190.443 201.136 1.00 16.58  ? 317 PHE A CG  1 
ATOM   747  C CD1 . PHE A 1 317 ? 205.859 189.440 200.346 1.00 16.18  ? 317 PHE A CD1 1 
ATOM   748  C CD2 . PHE A 1 317 ? 204.676 190.093 202.305 1.00 41.23  ? 317 PHE A CD2 1 
ATOM   749  C CE1 . PHE A 1 317 ? 205.750 188.116 200.721 1.00 36.04  ? 317 PHE A CE1 1 
ATOM   750  C CE2 . PHE A 1 317 ? 204.564 188.771 202.684 1.00 37.02  ? 317 PHE A CE2 1 
ATOM   751  C CZ  . PHE A 1 317 ? 205.101 187.781 201.891 1.00 36.85  ? 317 PHE A CZ  1 
ATOM   752  N N   . GLU A 1 318 ? 206.830 194.685 200.115 1.00 49.71  ? 318 GLU A N   1 
ATOM   753  C CA  . GLU A 1 318 ? 206.753 196.008 199.506 1.00 38.77  ? 318 GLU A CA  1 
ATOM   754  C C   . GLU A 1 318 ? 207.880 196.224 198.506 1.00 39.75  ? 318 GLU A C   1 
ATOM   755  O O   . GLU A 1 318 ? 207.648 196.677 197.378 1.00 44.88  ? 318 GLU A O   1 
ATOM   756  C CB  . GLU A 1 318 ? 206.794 197.079 200.594 1.00 29.77  ? 318 GLU A CB  1 
ATOM   757  C CG  . GLU A 1 318 ? 206.393 198.463 200.131 1.00 37.17  ? 318 GLU A CG  1 
ATOM   758  C CD  . GLU A 1 318 ? 206.493 199.489 201.240 1.00 50.11  ? 318 GLU A CD  1 
ATOM   759  O OE1 . GLU A 1 318 ? 205.854 199.290 202.294 1.00 45.77  ? 318 GLU A OE1 1 
ATOM   760  O OE2 . GLU A 1 318 ? 207.215 200.492 201.059 1.00 53.04  ? 318 GLU A OE2 1 
ATOM   761  N N   . ILE A 1 319 ? 209.115 195.917 198.906 1.00 30.32  ? 319 ILE A N   1 
ATOM   762  C CA  . ILE A 1 319 ? 210.242 196.149 198.006 1.00 30.72  ? 319 ILE A CA  1 
ATOM   763  C C   . ILE A 1 319 ? 210.187 195.188 196.823 1.00 37.89  ? 319 ILE A C   1 
ATOM   764  O O   . ILE A 1 319 ? 210.488 195.570 195.683 1.00 41.33  ? 319 ILE A O   1 
ATOM   765  C CB  . ILE A 1 319 ? 211.582 196.063 198.762 1.00 31.06  ? 319 ILE A CB  1 
ATOM   766  C CG1 . ILE A 1 319 ? 212.752 196.206 197.789 1.00 32.77  ? 319 ILE A CG1 1 
ATOM   767  C CG2 . ILE A 1 319 ? 211.704 194.764 199.525 1.00 35.37  ? 319 ILE A CG2 1 
ATOM   768  C CD1 . ILE A 1 319 ? 212.720 197.487 196.990 1.00 30.66  ? 319 ILE A CD1 1 
ATOM   769  N N   . ALA A 1 320 ? 209.777 193.937 197.060 1.00 29.59  ? 320 ALA A N   1 
ATOM   770  C CA  . ALA A 1 320 ? 209.613 192.999 195.955 1.00 20.99  ? 320 ALA A CA  1 
ATOM   771  C C   . ALA A 1 320 ? 208.564 193.495 194.971 1.00 34.02  ? 320 ALA A C   1 
ATOM   772  O O   . ALA A 1 320 ? 208.771 193.441 193.755 1.00 40.51  ? 320 ALA A O   1 
ATOM   773  C CB  . ALA A 1 320 ? 209.239 191.617 196.487 1.00 17.99  ? 320 ALA A CB  1 
ATOM   774  N N   . GLY A 1 321 ? 207.442 194.006 195.481 1.00 32.77  ? 321 GLY A N   1 
ATOM   775  C CA  . GLY A 1 321 ? 206.404 194.513 194.602 1.00 21.16  ? 321 GLY A CA  1 
ATOM   776  C C   . GLY A 1 321 ? 206.842 195.732 193.816 1.00 20.39  ? 321 GLY A C   1 
ATOM   777  O O   . GLY A 1 321 ? 206.550 195.844 192.627 1.00 24.32  ? 321 GLY A O   1 
ATOM   778  N N   . PHE A 1 322 ? 207.551 196.659 194.464 1.00 20.45  ? 322 PHE A N   1 
ATOM   779  C CA  . PHE A 1 322 ? 208.008 197.856 193.759 1.00 19.09  ? 322 PHE A CA  1 
ATOM   780  C C   . PHE A 1 322 ? 209.026 197.511 192.676 1.00 34.07  ? 322 PHE A C   1 
ATOM   781  O O   . PHE A 1 322 ? 208.949 198.024 191.548 1.00 51.72  ? 322 PHE A O   1 
ATOM   782  C CB  . PHE A 1 322 ? 208.598 198.853 194.754 1.00 21.29  ? 322 PHE A CB  1 
ATOM   783  C CG  . PHE A 1 322 ? 209.365 199.969 194.109 1.00 28.62  ? 322 PHE A CG  1 
ATOM   784  C CD1 . PHE A 1 322 ? 208.724 200.887 193.295 1.00 39.73  ? 322 PHE A CD1 1 
ATOM   785  C CD2 . PHE A 1 322 ? 210.726 200.102 194.319 1.00 23.98  ? 322 PHE A CD2 1 
ATOM   786  C CE1 . PHE A 1 322 ? 209.426 201.916 192.701 1.00 40.76  ? 322 PHE A CE1 1 
ATOM   787  C CE2 . PHE A 1 322 ? 211.434 201.130 193.727 1.00 30.91  ? 322 PHE A CE2 1 
ATOM   788  C CZ  . PHE A 1 322 ? 210.783 202.038 192.917 1.00 40.61  ? 322 PHE A CZ  1 
ATOM   789  N N   . LEU A 1 323 ? 209.988 196.643 192.995 1.00 36.40  ? 323 LEU A N   1 
ATOM   790  C CA  . LEU A 1 323 ? 210.957 196.234 191.987 1.00 39.59  ? 323 LEU A CA  1 
ATOM   791  C C   . LEU A 1 323 ? 210.292 195.445 190.866 1.00 34.96  ? 323 LEU A C   1 
ATOM   792  O O   . LEU A 1 323 ? 210.691 195.570 189.702 1.00 38.68  ? 323 LEU A O   1 
ATOM   793  C CB  . LEU A 1 323 ? 212.077 195.428 192.640 1.00 39.10  ? 323 LEU A CB  1 
ATOM   794  C CG  . LEU A 1 323 ? 213.053 196.221 193.509 1.00 44.34  ? 323 LEU A CG  1 
ATOM   795  C CD1 . LEU A 1 323 ? 214.115 195.306 194.095 1.00 42.22  ? 323 LEU A CD1 1 
ATOM   796  C CD2 . LEU A 1 323 ? 213.688 197.342 192.704 1.00 44.30  ? 323 LEU A CD2 1 
ATOM   797  N N   . GLY A 1 324 ? 209.272 194.645 191.185 1.00 36.28  ? 324 GLY A N   1 
ATOM   798  C CA  . GLY A 1 324 ? 208.496 193.997 190.145 1.00 30.17  ? 324 GLY A CA  1 
ATOM   799  C C   . GLY A 1 324 ? 207.730 194.977 189.283 1.00 32.82  ? 324 GLY A C   1 
ATOM   800  O O   . GLY A 1 324 ? 207.568 194.753 188.083 1.00 38.73  ? 324 GLY A O   1 
ATOM   801  N N   . ILE A 1 325 ? 207.244 196.069 189.878 1.00 32.20  ? 325 ILE A N   1 
ATOM   802  C CA  . ILE A 1 325 ? 206.605 197.125 189.097 1.00 36.51  ? 325 ILE A CA  1 
ATOM   803  C C   . ILE A 1 325 ? 207.593 197.689 188.090 1.00 35.82  ? 325 ILE A C   1 
ATOM   804  O O   . ILE A 1 325 ? 207.281 197.854 186.904 1.00 41.53  ? 325 ILE A O   1 
ATOM   805  C CB  . ILE A 1 325 ? 206.068 198.237 190.018 1.00 37.10  ? 325 ILE A CB  1 
ATOM   806  C CG1 . ILE A 1 325 ? 204.932 197.726 190.898 1.00 40.75  ? 325 ILE A CG1 1 
ATOM   807  C CG2 . ILE A 1 325 ? 205.603 199.431 189.199 1.00 28.01  ? 325 ILE A CG2 1 
ATOM   808  C CD1 . ILE A 1 325 ? 204.058 196.735 190.225 1.00 41.13  ? 325 ILE A CD1 1 
ATOM   809  N N   . LEU A 1 326 ? 208.806 197.989 188.558 1.00 26.41  ? 326 LEU A N   1 
ATOM   810  C CA  . LEU A 1 326 ? 209.829 198.520 187.662 1.00 26.84  ? 326 LEU A CA  1 
ATOM   811  C C   . LEU A 1 326 ? 210.160 197.530 186.551 1.00 36.71  ? 326 LEU A C   1 
ATOM   812  O O   . LEU A 1 326 ? 210.262 197.909 185.377 1.00 42.30  ? 326 LEU A O   1 
ATOM   813  C CB  . LEU A 1 326 ? 211.083 198.875 188.456 1.00 19.60  ? 326 LEU A CB  1 
ATOM   814  C CG  . LEU A 1 326 ? 210.934 200.057 189.411 1.00 35.00  ? 326 LEU A CG  1 
ATOM   815  C CD1 . LEU A 1 326 ? 212.256 200.355 190.090 1.00 39.33  ? 326 LEU A CD1 1 
ATOM   816  C CD2 . LEU A 1 326 ? 210.419 201.280 188.671 1.00 32.65  ? 326 LEU A CD2 1 
ATOM   817  N N   . TRP A 1 327 ? 210.322 196.252 186.904 1.00 38.02  ? 327 TRP A N   1 
ATOM   818  C CA  . TRP A 1 327 ? 210.657 195.238 185.909 1.00 22.61  ? 327 TRP A CA  1 
ATOM   819  C C   . TRP A 1 327 ? 209.546 195.077 184.878 1.00 27.56  ? 327 TRP A C   1 
ATOM   820  O O   . TRP A 1 327 ? 209.815 194.986 183.674 1.00 41.06  ? 327 TRP A O   1 
ATOM   821  C CB  . TRP A 1 327 ? 210.943 193.906 186.603 1.00 28.53  ? 327 TRP A CB  1 
ATOM   822  C CG  . TRP A 1 327 ? 211.144 192.761 185.665 1.00 20.42  ? 327 TRP A CG  1 
ATOM   823  C CD1 . TRP A 1 327 ? 212.272 192.469 184.959 1.00 30.26  ? 327 TRP A CD1 1 
ATOM   824  C CD2 . TRP A 1 327 ? 210.189 191.746 185.333 1.00 23.08  ? 327 TRP A CD2 1 
ATOM   825  N NE1 . TRP A 1 327 ? 212.080 191.337 184.207 1.00 38.77  ? 327 TRP A NE1 1 
ATOM   826  C CE2 . TRP A 1 327 ? 210.808 190.874 184.419 1.00 34.17  ? 327 TRP A CE2 1 
ATOM   827  C CE3 . TRP A 1 327 ? 208.871 191.492 185.721 1.00 28.20  ? 327 TRP A CE3 1 
ATOM   828  C CZ2 . TRP A 1 327 ? 210.155 189.767 183.885 1.00 32.91  ? 327 TRP A CZ2 1 
ATOM   829  C CZ3 . TRP A 1 327 ? 208.224 190.392 185.190 1.00 24.40  ? 327 TRP A CZ3 1 
ATOM   830  C CH2 . TRP A 1 327 ? 208.866 189.544 184.282 1.00 26.31  ? 327 TRP A CH2 1 
ATOM   831  N N   . CYS A 1 328 ? 208.291 195.035 185.331 1.00 32.42  ? 328 CYS A N   1 
ATOM   832  C CA  . CYS A 1 328 ? 207.171 194.880 184.410 1.00 34.11  ? 328 CYS A CA  1 
ATOM   833  C C   . CYS A 1 328 ? 207.032 196.092 183.501 1.00 39.39  ? 328 CYS A C   1 
ATOM   834  O O   . CYS A 1 328 ? 206.750 195.945 182.307 1.00 39.68  ? 328 CYS A O   1 
ATOM   835  C CB  . CYS A 1 328 ? 205.879 194.639 185.188 1.00 32.83  ? 328 CYS A CB  1 
ATOM   836  S SG  . CYS A 1 328 ? 205.445 192.897 185.386 1.00 34.73  ? 328 CYS A SG  1 
ATOM   837  N N   . LEU A 1 329 ? 207.223 197.298 184.043 1.00 47.67  ? 329 LEU A N   1 
ATOM   838  C CA  . LEU A 1 329 ? 207.170 198.491 183.205 1.00 45.59  ? 329 LEU A CA  1 
ATOM   839  C C   . LEU A 1 329 ? 208.278 198.475 182.161 1.00 46.07  ? 329 LEU A C   1 
ATOM   840  O O   . LEU A 1 329 ? 208.043 198.808 180.993 1.00 49.87  ? 329 LEU A O   1 
ATOM   841  C CB  . LEU A 1 329 ? 207.262 199.749 184.069 1.00 38.08  ? 329 LEU A CB  1 
ATOM   842  C CG  . LEU A 1 329 ? 206.018 200.099 184.888 1.00 28.51  ? 329 LEU A CG  1 
ATOM   843  C CD1 . LEU A 1 329 ? 206.221 201.405 185.637 1.00 35.91  ? 329 LEU A CD1 1 
ATOM   844  C CD2 . LEU A 1 329 ? 204.793 200.175 183.994 1.00 42.12  ? 329 LEU A CD2 1 
ATOM   845  N N   . SER A 1 330 ? 209.490 198.078 182.559 1.00 39.51  ? 330 SER A N   1 
ATOM   846  C CA  . SER A 1 330 ? 210.590 198.010 181.603 1.00 46.07  ? 330 SER A CA  1 
ATOM   847  C C   . SER A 1 330 ? 210.311 196.985 180.511 1.00 48.67  ? 330 SER A C   1 
ATOM   848  O O   . SER A 1 330 ? 210.545 197.252 179.327 1.00 53.49  ? 330 SER A O   1 
ATOM   849  C CB  . SER A 1 330 ? 211.895 197.681 182.327 1.00 50.04  ? 330 SER A CB  1 
ATOM   850  O OG  . SER A 1 330 ? 212.992 197.697 181.430 1.00 53.99  ? 330 SER A OG  1 
ATOM   851  N N   . LEU A 1 331 ? 209.798 195.811 180.886 1.00 36.38  ? 331 LEU A N   1 
ATOM   852  C CA  . LEU A 1 331 ? 209.498 194.786 179.890 1.00 37.88  ? 331 LEU A CA  1 
ATOM   853  C C   . LEU A 1 331 ? 208.391 195.236 178.945 1.00 50.84  ? 331 LEU A C   1 
ATOM   854  O O   . LEU A 1 331 ? 208.478 195.023 177.729 1.00 50.92  ? 331 LEU A O   1 
ATOM   855  C CB  . LEU A 1 331 ? 209.117 193.477 180.581 1.00 35.19  ? 331 LEU A CB  1 
ATOM   856  C CG  . LEU A 1 331 ? 209.287 192.206 179.745 1.00 41.20  ? 331 LEU A CG  1 
ATOM   857  C CD1 . LEU A 1 331 ? 210.590 192.248 178.965 1.00 47.10  ? 331 LEU A CD1 1 
ATOM   858  C CD2 . LEU A 1 331 ? 209.231 190.969 180.623 1.00 44.89  ? 331 LEU A CD2 1 
ATOM   859  N N   . LEU A 1 332 ? 207.338 195.856 179.484 1.00 50.25  ? 332 LEU A N   1 
ATOM   860  C CA  . LEU A 1 332 ? 206.247 196.334 178.643 1.00 45.46  ? 332 LEU A CA  1 
ATOM   861  C C   . LEU A 1 332 ? 206.724 197.410 177.679 1.00 47.20  ? 332 LEU A C   1 
ATOM   862  O O   . LEU A 1 332 ? 206.344 197.414 176.502 1.00 57.55  ? 332 LEU A O   1 
ATOM   863  C CB  . LEU A 1 332 ? 205.108 196.862 179.513 1.00 53.27  ? 332 LEU A CB  1 
ATOM   864  C CG  . LEU A 1 332 ? 203.893 195.946 179.650 1.00 53.42  ? 332 LEU A CG  1 
ATOM   865  C CD1 . LEU A 1 332 ? 202.770 196.674 180.359 1.00 46.56  ? 332 LEU A CD1 1 
ATOM   866  C CD2 . LEU A 1 332 ? 203.441 195.444 178.289 1.00 51.91  ? 332 LEU A CD2 1 
ATOM   867  N N   . ALA A 1 333 ? 207.555 198.337 178.161 1.00 49.36  ? 333 ALA A N   1 
ATOM   868  C CA  . ALA A 1 333 ? 208.089 199.371 177.284 1.00 57.10  ? 333 ALA A CA  1 
ATOM   869  C C   . ALA A 1 333 ? 209.033 198.784 176.242 1.00 65.47  ? 333 ALA A C   1 
ATOM   870  O O   . ALA A 1 333 ? 209.126 199.306 175.125 1.00 72.78  ? 333 ALA A O   1 
ATOM   871  C CB  . ALA A 1 333 ? 208.794 200.441 178.114 1.00 56.99  ? 333 ALA A CB  1 
ATOM   872  N N   . CYS A 1 334 ? 209.741 197.705 176.586 1.00 64.64  ? 334 CYS A N   1 
ATOM   873  C CA  . CYS A 1 334 ? 210.581 197.027 175.606 1.00 65.93  ? 334 CYS A CA  1 
ATOM   874  C C   . CYS A 1 334 ? 209.740 196.332 174.543 1.00 65.44  ? 334 CYS A C   1 
ATOM   875  O O   . CYS A 1 334 ? 210.152 196.240 173.381 1.00 65.66  ? 334 CYS A O   1 
ATOM   876  C CB  . CYS A 1 334 ? 211.494 196.020 176.304 1.00 65.22  ? 334 CYS A CB  1 
ATOM   877  S SG  . CYS A 1 334 ? 213.167 196.612 176.622 1.00 81.67  ? 334 CYS A SG  1 
ATOM   878  N N   . PHE A 1 335 ? 208.566 195.824 174.926 1.00 59.25  ? 335 PHE A N   1 
ATOM   879  C CA  . PHE A 1 335 ? 207.712 195.129 173.968 1.00 58.81  ? 335 PHE A CA  1 
ATOM   880  C C   . PHE A 1 335 ? 207.265 196.066 172.852 1.00 61.05  ? 335 PHE A C   1 
ATOM   881  O O   . PHE A 1 335 ? 207.383 195.740 171.665 1.00 64.48  ? 335 PHE A O   1 
ATOM   882  C CB  . PHE A 1 335 ? 206.506 194.526 174.686 1.00 58.23  ? 335 PHE A CB  1 
ATOM   883  C CG  . PHE A 1 335 ? 206.627 193.052 174.933 1.00 55.54  ? 335 PHE A CG  1 
ATOM   884  C CD1 . PHE A 1 335 ? 207.316 192.578 176.035 1.00 57.89  ? 335 PHE A CD1 1 
ATOM   885  C CD2 . PHE A 1 335 ? 206.061 192.141 174.059 1.00 57.38  ? 335 PHE A CD2 1 
ATOM   886  C CE1 . PHE A 1 335 ? 207.433 191.222 176.266 1.00 57.70  ? 335 PHE A CE1 1 
ATOM   887  C CE2 . PHE A 1 335 ? 206.177 190.784 174.284 1.00 59.88  ? 335 PHE A CE2 1 
ATOM   888  C CZ  . PHE A 1 335 ? 206.862 190.324 175.390 1.00 59.85  ? 335 PHE A CZ  1 
ATOM   889  N N   . PHE A 1 336 ? 206.748 197.238 173.214 1.00 62.93  ? 336 PHE A N   1 
ATOM   890  C CA  . PHE A 1 336 ? 206.432 198.295 172.257 1.00 65.21  ? 336 PHE A CA  1 
ATOM   891  C C   . PHE A 1 336 ? 206.967 199.606 172.816 1.00 67.12  ? 336 PHE A C   1 
ATOM   892  O O   . PHE A 1 336 ? 206.541 200.048 173.887 1.00 63.80  ? 336 PHE A O   1 
ATOM   893  C CB  . PHE A 1 336 ? 204.928 198.379 171.984 1.00 65.49  ? 336 PHE A CB  1 
ATOM   894  C CG  . PHE A 1 336 ? 204.067 197.926 173.131 1.00 63.46  ? 336 PHE A CG  1 
ATOM   895  C CD1 . PHE A 1 336 ? 203.838 198.754 174.216 1.00 62.38  ? 336 PHE A CD1 1 
ATOM   896  C CD2 . PHE A 1 336 ? 203.478 196.674 173.116 1.00 62.16  ? 336 PHE A CD2 1 
ATOM   897  C CE1 . PHE A 1 336 ? 203.044 198.339 175.267 1.00 62.56  ? 336 PHE A CE1 1 
ATOM   898  C CE2 . PHE A 1 336 ? 202.683 196.254 174.165 1.00 64.95  ? 336 PHE A CE2 1 
ATOM   899  C CZ  . PHE A 1 336 ? 202.466 197.088 175.241 1.00 63.81  ? 336 PHE A CZ  1 
ATOM   900  N N   . ALA A 1 337 ? 207.901 200.218 172.103 1.00 79.31  ? 337 ALA A N   1 
ATOM   901  C CA  . ALA A 1 337 ? 208.535 201.434 172.594 1.00 80.47  ? 337 ALA A CA  1 
ATOM   902  C C   . ALA A 1 337 ? 207.550 202.594 172.553 1.00 80.86  ? 337 ALA A C   1 
ATOM   903  O O   . ALA A 1 337 ? 207.055 202.936 171.470 1.00 79.92  ? 337 ALA A O   1 
ATOM   904  C CB  . ALA A 1 337 ? 209.773 201.759 171.763 1.00 79.02  ? 337 ALA A CB  1 
ATOM   905  N N   . PRO A 1 338 ? 207.228 203.216 173.690 1.00 87.36  ? 338 PRO A N   1 
ATOM   906  C CA  . PRO A 1 338 ? 206.339 204.388 173.643 1.00 89.50  ? 338 PRO A CA  1 
ATOM   907  C C   . PRO A 1 338 ? 206.937 205.556 172.882 1.00 89.91  ? 338 PRO A C   1 
ATOM   908  O O   . PRO A 1 338 ? 206.202 206.298 172.218 1.00 88.23  ? 338 PRO A O   1 
ATOM   909  C CB  . PRO A 1 338 ? 206.117 204.724 175.127 1.00 85.86  ? 338 PRO A CB  1 
ATOM   910  C CG  . PRO A 1 338 ? 206.574 203.510 175.887 1.00 84.23  ? 338 PRO A CG  1 
ATOM   911  C CD  . PRO A 1 338 ? 207.654 202.897 175.061 1.00 83.94  ? 338 PRO A CD  1 
ATOM   912  N N   . ILE A 1 339 ? 208.251 205.741 172.957 1.00 93.99  ? 339 ILE A N   1 
ATOM   913  C CA  . ILE A 1 339 ? 208.931 206.863 172.320 1.00 92.03  ? 339 ILE A CA  1 
ATOM   914  C C   . ILE A 1 339 ? 209.829 206.317 171.219 1.00 93.57  ? 339 ILE A C   1 
ATOM   915  O O   . ILE A 1 339 ? 210.683 205.459 171.471 1.00 91.81  ? 339 ILE A O   1 
ATOM   916  C CB  . ILE A 1 339 ? 209.740 207.681 173.338 1.00 88.63  ? 339 ILE A CB  1 
ATOM   917  C CG1 . ILE A 1 339 ? 208.807 208.406 174.310 1.00 90.59  ? 339 ILE A CG1 1 
ATOM   918  C CG2 . ILE A 1 339 ? 210.639 208.678 172.623 1.00 90.05  ? 339 ILE A CG2 1 
ATOM   919  C CD1 . ILE A 1 339 ? 208.530 207.641 175.588 1.00 88.81  ? 339 ILE A CD1 1 
ATOM   920  N N   . SER A 1 340 ? 209.633 206.812 169.995 1.00 99.35  ? 340 SER A N   1 
ATOM   921  C CA  . SER A 1 340 ? 210.466 206.378 168.878 1.00 97.52  ? 340 SER A CA  1 
ATOM   922  C C   . SER A 1 340 ? 211.906 206.849 169.031 1.00 98.77  ? 340 SER A C   1 
ATOM   923  O O   . SER A 1 340 ? 212.834 206.138 168.630 1.00 97.57  ? 340 SER A O   1 
ATOM   924  C CB  . SER A 1 340 ? 209.880 206.883 167.560 1.00 98.34  ? 340 SER A CB  1 
ATOM   925  O OG  . SER A 1 340 ? 208.529 206.483 167.415 1.00 99.97  ? 340 SER A OG  1 
ATOM   926  N N   . VAL A 1 341 ? 212.111 208.042 169.596 1.00 101.71 ? 341 VAL A N   1 
ATOM   927  C CA  . VAL A 1 341 ? 213.462 208.576 169.748 1.00 101.98 ? 341 VAL A CA  1 
ATOM   928  C C   . VAL A 1 341 ? 214.280 207.708 170.697 1.00 102.72 ? 341 VAL A C   1 
ATOM   929  O O   . VAL A 1 341 ? 215.444 207.391 170.423 1.00 101.84 ? 341 VAL A O   1 
ATOM   930  C CB  . VAL A 1 341 ? 213.406 210.039 170.226 1.00 99.45  ? 341 VAL A CB  1 
ATOM   931  C CG1 . VAL A 1 341 ? 214.811 210.599 170.390 1.00 100.64 ? 341 VAL A CG1 1 
ATOM   932  C CG2 . VAL A 1 341 ? 212.599 210.884 169.254 1.00 98.64  ? 341 VAL A CG2 1 
ATOM   933  N N   . ILE A 1 342 ? 213.689 207.310 171.819 1.00 102.16 ? 342 ILE A N   1 
ATOM   934  C CA  . ILE A 1 342 ? 214.395 206.521 172.825 1.00 100.98 ? 342 ILE A CA  1 
ATOM   935  C C   . ILE A 1 342 ? 214.555 205.092 172.320 1.00 101.49 ? 342 ILE A C   1 
ATOM   936  O O   . ILE A 1 342 ? 213.557 204.437 171.985 1.00 100.98 ? 342 ILE A O   1 
ATOM   937  C CB  . ILE A 1 342 ? 213.661 206.551 174.174 1.00 99.13  ? 342 ILE A CB  1 
ATOM   938  C CG1 . ILE A 1 342 ? 213.570 207.984 174.700 1.00 100.30 ? 342 ILE A CG1 1 
ATOM   939  C CG2 . ILE A 1 342 ? 214.377 205.675 175.182 1.00 98.32  ? 342 ILE A CG2 1 
ATOM   940  C CD1 . ILE A 1 342 ? 212.721 208.122 175.944 1.00 100.85 ? 342 ILE A CD1 1 
ATOM   941  N N   . PRO A 1 343 ? 215.778 204.573 172.244 1.00 106.86 ? 343 PRO A N   1 
ATOM   942  C CA  . PRO A 1 343 ? 215.973 203.199 171.769 1.00 106.91 ? 343 PRO A CA  1 
ATOM   943  C C   . PRO A 1 343 ? 215.388 202.182 172.736 1.00 104.48 ? 343 PRO A C   1 
ATOM   944  O O   . PRO A 1 343 ? 215.294 202.405 173.945 1.00 102.17 ? 343 PRO A O   1 
ATOM   945  C CB  . PRO A 1 343 ? 217.498 203.061 171.677 1.00 105.09 ? 343 PRO A CB  1 
ATOM   946  C CG  . PRO A 1 343 ? 218.037 204.460 171.755 1.00 105.65 ? 343 PRO A CG  1 
ATOM   947  C CD  . PRO A 1 343 ? 217.052 205.236 172.563 1.00 106.13 ? 343 PRO A CD  1 
ATOM   948  N N   . THR A 1 344 ? 214.988 201.040 172.175 1.00 100.53 ? 344 THR A N   1 
ATOM   949  C CA  . THR A 1 344 ? 214.387 199.981 172.975 1.00 99.66  ? 344 THR A CA  1 
ATOM   950  C C   . THR A 1 344 ? 215.407 199.209 173.802 1.00 102.52 ? 344 THR A C   1 
ATOM   951  O O   . THR A 1 344 ? 215.015 198.503 174.737 1.00 102.45 ? 344 THR A O   1 
ATOM   952  C CB  . THR A 1 344 ? 213.623 199.004 172.078 1.00 100.18 ? 344 THR A CB  1 
ATOM   953  O OG1 . THR A 1 344 ? 212.867 198.098 172.890 1.00 97.49  ? 344 THR A OG1 1 
ATOM   954  C CG2 . THR A 1 344 ? 214.589 198.210 171.215 1.00 102.15 ? 344 THR A CG2 1 
ATOM   955  N N   . TYR A 1 345 ? 216.698 199.320 173.485 1.00 105.35 ? 345 TYR A N   1 
ATOM   956  C CA  . TYR A 1 345 ? 217.710 198.583 174.230 1.00 103.19 ? 345 TYR A CA  1 
ATOM   957  C C   . TYR A 1 345 ? 218.169 199.301 175.492 1.00 101.44 ? 345 TYR A C   1 
ATOM   958  O O   . TYR A 1 345 ? 218.829 198.678 176.329 1.00 104.82 ? 345 TYR A O   1 
ATOM   959  C CB  . TYR A 1 345 ? 218.916 198.279 173.332 1.00 103.72 ? 345 TYR A CB  1 
ATOM   960  C CG  . TYR A 1 345 ? 219.560 199.485 172.679 1.00 104.33 ? 345 TYR A CG  1 
ATOM   961  C CD1 . TYR A 1 345 ? 220.318 200.386 173.417 1.00 104.01 ? 345 TYR A CD1 1 
ATOM   962  C CD2 . TYR A 1 345 ? 219.421 199.712 171.316 1.00 103.72 ? 345 TYR A CD2 1 
ATOM   963  C CE1 . TYR A 1 345 ? 220.908 201.482 172.819 1.00 105.60 ? 345 TYR A CE1 1 
ATOM   964  C CE2 . TYR A 1 345 ? 220.009 200.804 170.709 1.00 103.95 ? 345 TYR A CE2 1 
ATOM   965  C CZ  . TYR A 1 345 ? 220.751 201.686 171.465 1.00 104.92 ? 345 TYR A CZ  1 
ATOM   966  O OH  . TYR A 1 345 ? 221.338 202.776 170.865 1.00 104.95 ? 345 TYR A OH  1 
ATOM   967  N N   . VAL A 1 346 ? 217.842 200.586 175.654 1.00 89.61  ? 346 VAL A N   1 
ATOM   968  C CA  . VAL A 1 346 ? 218.235 201.315 176.858 1.00 91.73  ? 346 VAL A CA  1 
ATOM   969  C C   . VAL A 1 346 ? 217.316 201.022 178.035 1.00 91.18  ? 346 VAL A C   1 
ATOM   970  O O   . VAL A 1 346 ? 217.650 201.381 179.174 1.00 89.19  ? 346 VAL A O   1 
ATOM   971  C CB  . VAL A 1 346 ? 218.274 202.834 176.589 1.00 93.03  ? 346 VAL A CB  1 
ATOM   972  C CG1 . VAL A 1 346 ? 216.875 203.426 176.652 1.00 91.01  ? 346 VAL A CG1 1 
ATOM   973  C CG2 . VAL A 1 346 ? 219.218 203.535 177.561 1.00 90.83  ? 346 VAL A CG2 1 
ATOM   974  N N   . TYR A 1 347 ? 216.168 200.392 177.798 1.00 84.32  ? 347 TYR A N   1 
ATOM   975  C CA  . TYR A 1 347 ? 215.234 200.096 178.883 1.00 84.29  ? 347 TYR A CA  1 
ATOM   976  C C   . TYR A 1 347 ? 215.789 199.102 179.899 1.00 82.31  ? 347 TYR A C   1 
ATOM   977  O O   . TYR A 1 347 ? 215.634 199.345 181.110 1.00 79.29  ? 347 TYR A O   1 
ATOM   978  C CB  . TYR A 1 347 ? 213.907 199.624 178.281 1.00 80.70  ? 347 TYR A CB  1 
ATOM   979  C CG  . TYR A 1 347 ? 213.166 200.710 177.531 1.00 82.22  ? 347 TYR A CG  1 
ATOM   980  C CD1 . TYR A 1 347 ? 213.590 202.031 177.582 1.00 83.63  ? 347 TYR A CD1 1 
ATOM   981  C CD2 . TYR A 1 347 ? 212.026 200.419 176.796 1.00 82.56  ? 347 TYR A CD2 1 
ATOM   982  C CE1 . TYR A 1 347 ? 212.917 203.025 176.905 1.00 86.93  ? 347 TYR A CE1 1 
ATOM   983  C CE2 . TYR A 1 347 ? 211.349 201.409 176.108 1.00 85.94  ? 347 TYR A CE2 1 
ATOM   984  C CZ  . TYR A 1 347 ? 211.795 202.709 176.171 1.00 88.44  ? 347 TYR A CZ  1 
ATOM   985  O OH  . TYR A 1 347 ? 211.120 203.698 175.495 1.00 90.63  ? 347 TYR A OH  1 
ATOM   986  N N   . PRO A 1 348 ? 216.396 197.970 179.508 1.00 76.42  ? 348 PRO A N   1 
ATOM   987  C CA  . PRO A 1 348 ? 217.047 197.128 180.527 1.00 70.35  ? 348 PRO A CA  1 
ATOM   988  C C   . PRO A 1 348 ? 218.159 197.849 181.266 1.00 75.79  ? 348 PRO A C   1 
ATOM   989  O O   . PRO A 1 348 ? 218.334 197.641 182.475 1.00 84.12  ? 348 PRO A O   1 
ATOM   990  C CB  . PRO A 1 348 ? 217.576 195.933 179.720 1.00 67.20  ? 348 PRO A CB  1 
ATOM   991  C CG  . PRO A 1 348 ? 216.814 195.942 178.452 1.00 75.47  ? 348 PRO A CG  1 
ATOM   992  C CD  . PRO A 1 348 ? 216.485 197.367 178.166 1.00 79.47  ? 348 PRO A CD  1 
ATOM   993  N N   . LEU A 1 349 ? 218.916 198.702 180.568 1.00 75.61  ? 349 LEU A N   1 
ATOM   994  C CA  . LEU A 1 349 ? 219.923 199.509 181.247 1.00 80.63  ? 349 LEU A CA  1 
ATOM   995  C C   . LEU A 1 349 ? 219.286 200.384 182.312 1.00 80.10  ? 349 LEU A C   1 
ATOM   996  O O   . LEU A 1 349 ? 219.783 200.457 183.439 1.00 80.96  ? 349 LEU A O   1 
ATOM   997  C CB  . LEU A 1 349 ? 220.688 200.376 180.246 1.00 79.49  ? 349 LEU A CB  1 
ATOM   998  C CG  . LEU A 1 349 ? 222.146 200.692 180.605 1.00 79.19  ? 349 LEU A CG  1 
ATOM   999  C CD1 . LEU A 1 349 ? 222.973 200.979 179.364 1.00 80.66  ? 349 LEU A CD1 1 
ATOM   1000 C CD2 . LEU A 1 349 ? 222.238 201.858 181.582 1.00 76.94  ? 349 LEU A CD2 1 
ATOM   1001 N N   . ALA A 1 350 ? 218.179 201.048 181.976 1.00 67.34  ? 350 ALA A N   1 
ATOM   1002 C CA  . ALA A 1 350 ? 217.509 201.906 182.946 1.00 71.91  ? 350 ALA A CA  1 
ATOM   1003 C C   . ALA A 1 350 ? 217.002 201.101 184.133 1.00 76.91  ? 350 ALA A C   1 
ATOM   1004 O O   . ALA A 1 350 ? 217.169 201.512 185.285 1.00 78.23  ? 350 ALA A O   1 
ATOM   1005 C CB  . ALA A 1 350 ? 216.359 202.659 182.276 1.00 73.81  ? 350 ALA A CB  1 
ATOM   1006 N N   . LEU A 1 351 ? 216.400 199.939 183.871 1.00 70.01  ? 351 LEU A N   1 
ATOM   1007 C CA  . LEU A 1 351 ? 215.851 199.128 184.955 1.00 63.51  ? 351 LEU A CA  1 
ATOM   1008 C C   . LEU A 1 351 ? 216.947 198.663 185.909 1.00 60.27  ? 351 LEU A C   1 
ATOM   1009 O O   . LEU A 1 351 ? 216.846 198.845 187.130 1.00 63.03  ? 351 LEU A O   1 
ATOM   1010 C CB  . LEU A 1 351 ? 215.092 197.931 184.382 1.00 60.23  ? 351 LEU A CB  1 
ATOM   1011 C CG  . LEU A 1 351 ? 214.852 196.759 185.337 1.00 51.44  ? 351 LEU A CG  1 
ATOM   1012 C CD1 . LEU A 1 351 ? 213.851 197.142 186.414 1.00 52.95  ? 351 LEU A CD1 1 
ATOM   1013 C CD2 . LEU A 1 351 ? 214.379 195.531 184.577 1.00 53.32  ? 351 LEU A CD2 1 
ATOM   1014 N N   . TYR A 1 352 ? 218.014 198.071 185.368 1.00 57.55  ? 352 TYR A N   1 
ATOM   1015 C CA  . TYR A 1 352 ? 219.063 197.546 186.235 1.00 59.53  ? 352 TYR A CA  1 
ATOM   1016 C C   . TYR A 1 352 ? 219.882 198.659 186.878 1.00 68.53  ? 352 TYR A C   1 
ATOM   1017 O O   . TYR A 1 352 ? 220.341 198.504 188.016 1.00 75.58  ? 352 TYR A O   1 
ATOM   1018 C CB  . TYR A 1 352 ? 219.955 196.582 185.456 1.00 58.56  ? 352 TYR A CB  1 
ATOM   1019 C CG  . TYR A 1 352 ? 219.234 195.313 185.062 1.00 59.36  ? 352 TYR A CG  1 
ATOM   1020 C CD1 . TYR A 1 352 ? 218.672 194.487 186.026 1.00 60.29  ? 352 TYR A CD1 1 
ATOM   1021 C CD2 . TYR A 1 352 ? 219.101 194.949 183.732 1.00 66.87  ? 352 TYR A CD2 1 
ATOM   1022 C CE1 . TYR A 1 352 ? 218.008 193.329 185.674 1.00 67.09  ? 352 TYR A CE1 1 
ATOM   1023 C CE2 . TYR A 1 352 ? 218.438 193.793 183.370 1.00 68.89  ? 352 TYR A CE2 1 
ATOM   1024 C CZ  . TYR A 1 352 ? 217.893 192.987 184.345 1.00 71.29  ? 352 TYR A CZ  1 
ATOM   1025 O OH  . TYR A 1 352 ? 217.232 191.835 183.989 1.00 70.66  ? 352 TYR A OH  1 
ATOM   1026 N N   . GLY A 1 353 ? 220.062 199.787 186.190 1.00 67.60  ? 353 GLY A N   1 
ATOM   1027 C CA  . GLY A 1 353 ? 220.715 200.922 186.814 1.00 70.61  ? 353 GLY A CA  1 
ATOM   1028 C C   . GLY A 1 353 ? 219.904 201.493 187.959 1.00 72.75  ? 353 GLY A C   1 
ATOM   1029 O O   . GLY A 1 353 ? 220.459 201.867 188.992 1.00 71.83  ? 353 GLY A O   1 
ATOM   1030 N N   . PHE A 1 354 ? 218.580 201.563 187.798 1.00 68.81  ? 354 PHE A N   1 
ATOM   1031 C CA  . PHE A 1 354 ? 217.731 202.001 188.898 1.00 65.49  ? 354 PHE A CA  1 
ATOM   1032 C C   . PHE A 1 354 ? 217.802 201.023 190.062 1.00 68.99  ? 354 PHE A C   1 
ATOM   1033 O O   . PHE A 1 354 ? 217.840 201.438 191.225 1.00 72.89  ? 354 PHE A O   1 
ATOM   1034 C CB  . PHE A 1 354 ? 216.289 202.164 188.417 1.00 61.96  ? 354 PHE A CB  1 
ATOM   1035 C CG  . PHE A 1 354 ? 215.440 203.014 189.320 1.00 64.14  ? 354 PHE A CG  1 
ATOM   1036 C CD1 . PHE A 1 354 ? 214.940 202.508 190.508 1.00 66.82  ? 354 PHE A CD1 1 
ATOM   1037 C CD2 . PHE A 1 354 ? 215.142 204.322 188.979 1.00 69.59  ? 354 PHE A CD2 1 
ATOM   1038 C CE1 . PHE A 1 354 ? 214.160 203.289 191.338 1.00 71.57  ? 354 PHE A CE1 1 
ATOM   1039 C CE2 . PHE A 1 354 ? 214.362 205.109 189.805 1.00 69.41  ? 354 PHE A CE2 1 
ATOM   1040 C CZ  . PHE A 1 354 ? 213.871 204.592 190.986 1.00 71.85  ? 354 PHE A CZ  1 
ATOM   1041 N N   . MET A 1 355 ? 217.822 199.721 189.767 1.00 66.48  ? 355 MET A N   1 
ATOM   1042 C CA  . MET A 1 355 ? 217.949 198.726 190.829 1.00 62.33  ? 355 MET A CA  1 
ATOM   1043 C C   . MET A 1 355 ? 219.256 198.906 191.594 1.00 67.08  ? 355 MET A C   1 
ATOM   1044 O O   . MET A 1 355 ? 219.269 198.941 192.832 1.00 73.26  ? 355 MET A O   1 
ATOM   1045 C CB  . MET A 1 355 ? 217.863 197.319 190.237 1.00 59.27  ? 355 MET A CB  1 
ATOM   1046 C CG  . MET A 1 355 ? 216.527 196.631 190.447 1.00 60.89  ? 355 MET A CG  1 
ATOM   1047 S SD  . MET A 1 355 ? 216.444 195.038 189.607 1.00 76.78  ? 355 MET A SD  1 
ATOM   1048 C CE  . MET A 1 355 ? 214.678 194.744 189.607 1.00 56.01  ? 355 MET A CE  1 
ATOM   1049 N N   . VAL A 1 356 ? 220.368 199.046 190.869 1.00 70.26  ? 356 VAL A N   1 
ATOM   1050 C CA  . VAL A 1 356 ? 221.661 199.186 191.531 1.00 71.70  ? 356 VAL A CA  1 
ATOM   1051 C C   . VAL A 1 356 ? 221.749 200.513 192.278 1.00 76.29  ? 356 VAL A C   1 
ATOM   1052 O O   . VAL A 1 356 ? 222.358 200.583 193.351 1.00 74.02  ? 356 VAL A O   1 
ATOM   1053 C CB  . VAL A 1 356 ? 222.812 199.001 190.519 1.00 72.67  ? 356 VAL A CB  1 
ATOM   1054 C CG1 . VAL A 1 356 ? 223.159 200.303 189.809 1.00 72.45  ? 356 VAL A CG1 1 
ATOM   1055 C CG2 . VAL A 1 356 ? 224.038 198.426 191.214 1.00 72.82  ? 356 VAL A CG2 1 
ATOM   1056 N N   . PHE A 1 357 ? 221.138 201.578 191.745 1.00 82.49  ? 357 PHE A N   1 
ATOM   1057 C CA  . PHE A 1 357 ? 221.144 202.863 192.435 1.00 81.65  ? 357 PHE A CA  1 
ATOM   1058 C C   . PHE A 1 357 ? 220.339 202.793 193.723 1.00 81.44  ? 357 PHE A C   1 
ATOM   1059 O O   . PHE A 1 357 ? 220.743 203.355 194.747 1.00 80.70  ? 357 PHE A O   1 
ATOM   1060 C CB  . PHE A 1 357 ? 220.601 203.958 191.517 1.00 78.11  ? 357 PHE A CB  1 
ATOM   1061 C CG  . PHE A 1 357 ? 221.579 204.409 190.470 1.00 83.05  ? 357 PHE A CG  1 
ATOM   1062 C CD1 . PHE A 1 357 ? 222.942 204.358 190.711 1.00 84.22  ? 357 PHE A CD1 1 
ATOM   1063 C CD2 . PHE A 1 357 ? 221.136 204.889 189.249 1.00 81.91  ? 357 PHE A CD2 1 
ATOM   1064 C CE1 . PHE A 1 357 ? 223.845 204.772 189.751 1.00 82.37  ? 357 PHE A CE1 1 
ATOM   1065 C CE2 . PHE A 1 357 ? 222.034 205.305 188.285 1.00 82.24  ? 357 PHE A CE2 1 
ATOM   1066 C CZ  . PHE A 1 357 ? 223.390 205.247 188.537 1.00 81.82  ? 357 PHE A CZ  1 
ATOM   1067 N N   . PHE A 1 358 ? 219.193 202.111 193.689 1.00 74.27  ? 358 PHE A N   1 
ATOM   1068 C CA  . PHE A 1 358 ? 218.454 201.852 194.917 1.00 70.77  ? 358 PHE A CA  1 
ATOM   1069 C C   . PHE A 1 358 ? 219.282 201.020 195.885 1.00 71.01  ? 358 PHE A C   1 
ATOM   1070 O O   . PHE A 1 358 ? 219.134 201.156 197.105 1.00 70.74  ? 358 PHE A O   1 
ATOM   1071 C CB  . PHE A 1 358 ? 217.133 201.152 194.594 1.00 68.55  ? 358 PHE A CB  1 
ATOM   1072 C CG  . PHE A 1 358 ? 216.351 200.736 195.808 1.00 74.77  ? 358 PHE A CG  1 
ATOM   1073 C CD1 . PHE A 1 358 ? 215.453 201.609 196.397 1.00 77.42  ? 358 PHE A CD1 1 
ATOM   1074 C CD2 . PHE A 1 358 ? 216.504 199.471 196.352 1.00 73.48  ? 358 PHE A CD2 1 
ATOM   1075 C CE1 . PHE A 1 358 ? 214.731 201.231 197.510 1.00 75.75  ? 358 PHE A CE1 1 
ATOM   1076 C CE2 . PHE A 1 358 ? 215.787 199.092 197.467 1.00 72.47  ? 358 PHE A CE2 1 
ATOM   1077 C CZ  . PHE A 1 358 ? 214.898 199.973 198.047 1.00 74.20  ? 358 PHE A CZ  1 
ATOM   1078 N N   . LEU A 1 359 ? 220.153 200.155 195.363 1.00 74.65  ? 359 LEU A N   1 
ATOM   1079 C CA  . LEU A 1 359 ? 221.011 199.355 196.229 1.00 74.46  ? 359 LEU A CA  1 
ATOM   1080 C C   . LEU A 1 359 ? 222.171 200.161 196.808 1.00 77.56  ? 359 LEU A C   1 
ATOM   1081 O O   . LEU A 1 359 ? 222.618 199.874 197.923 1.00 76.27  ? 359 LEU A O   1 
ATOM   1082 C CB  . LEU A 1 359 ? 221.542 198.142 195.462 1.00 74.71  ? 359 LEU A CB  1 
ATOM   1083 C CG  . LEU A 1 359 ? 222.363 197.135 196.269 1.00 75.26  ? 359 LEU A CG  1 
ATOM   1084 C CD1 . LEU A 1 359 ? 221.559 196.634 197.456 1.00 70.29  ? 359 LEU A CD1 1 
ATOM   1085 C CD2 . LEU A 1 359 ? 222.810 195.976 195.394 1.00 80.10  ? 359 LEU A CD2 1 
ATOM   1086 N N   . ILE A 1 360 ? 222.670 201.166 196.081 1.00 85.60  ? 360 ILE A N   1 
ATOM   1087 C CA  . ILE A 1 360 ? 223.819 201.945 196.542 1.00 85.52  ? 360 ILE A CA  1 
ATOM   1088 C C   . ILE A 1 360 ? 223.397 203.295 197.122 1.00 87.14  ? 360 ILE A C   1 
ATOM   1089 O O   . ILE A 1 360 ? 224.236 203.994 197.714 1.00 90.51  ? 360 ILE A O   1 
ATOM   1090 C CB  . ILE A 1 360 ? 224.843 202.129 195.394 1.00 82.75  ? 360 ILE A CB  1 
ATOM   1091 C CG1 . ILE A 1 360 ? 226.087 202.910 195.827 1.00 83.16  ? 360 ILE A CG1 1 
ATOM   1092 C CG2 . ILE A 1 360 ? 224.215 202.882 194.243 1.00 79.99  ? 360 ILE A CG2 1 
ATOM   1093 C CD1 . ILE A 1 360 ? 226.920 202.206 196.873 1.00 82.44  ? 360 ILE A CD1 1 
ATOM   1094 N N   . ASN A 1 361 ? 222.111 203.654 197.024 1.00 90.21  ? 361 ASN A N   1 
ATOM   1095 C CA  . ASN A 1 361 ? 221.561 204.957 197.393 1.00 89.49  ? 361 ASN A CA  1 
ATOM   1096 C C   . ASN A 1 361 ? 222.109 205.452 198.727 1.00 92.13  ? 361 ASN A C   1 
ATOM   1097 O O   . ASN A 1 361 ? 221.820 204.865 199.777 1.00 92.73  ? 361 ASN A O   1 
ATOM   1098 C CB  . ASN A 1 361 ? 220.033 204.881 197.450 1.00 88.20  ? 361 ASN A CB  1 
ATOM   1099 C CG  . ASN A 1 361 ? 219.375 206.247 197.393 1.00 91.97  ? 361 ASN A CG  1 
ATOM   1100 O OD1 . ASN A 1 361 ? 219.809 207.188 198.055 1.00 92.45  ? 361 ASN A OD1 1 
ATOM   1101 N ND2 . ASN A 1 361 ? 218.318 206.358 196.598 1.00 92.63  ? 361 ASN A ND2 1 
ATOM   1102 N N   . PRO A 1 362 ? 222.901 206.526 198.724 1.00 90.75  ? 362 PRO A N   1 
ATOM   1103 C CA  . PRO A 1 362 ? 223.459 207.039 199.982 1.00 91.15  ? 362 PRO A CA  1 
ATOM   1104 C C   . PRO A 1 362 ? 222.451 207.853 200.777 1.00 90.06  ? 362 PRO A C   1 
ATOM   1105 O O   . PRO A 1 362 ? 222.550 207.944 202.005 1.00 87.43  ? 362 PRO A O   1 
ATOM   1106 C CB  . PRO A 1 362 ? 224.635 207.902 199.512 1.00 88.34  ? 362 PRO A CB  1 
ATOM   1107 C CG  . PRO A 1 362 ? 224.225 208.373 198.158 1.00 86.95  ? 362 PRO A CG  1 
ATOM   1108 C CD  . PRO A 1 362 ? 223.388 207.275 197.551 1.00 86.99  ? 362 PRO A CD  1 
ATOM   1109 N N   . THR A 1 363 ? 221.484 208.453 200.087 1.00 89.29  ? 363 THR A N   1 
ATOM   1110 C CA  . THR A 1 363 ? 220.447 209.219 200.765 1.00 89.34  ? 363 THR A CA  1 
ATOM   1111 C C   . THR A 1 363 ? 219.598 208.304 201.640 1.00 88.99  ? 363 THR A C   1 
ATOM   1112 O O   . THR A 1 363 ? 219.174 207.228 201.210 1.00 87.89  ? 363 THR A O   1 
ATOM   1113 C CB  . THR A 1 363 ? 219.573 209.947 199.744 1.00 90.98  ? 363 THR A CB  1 
ATOM   1114 O OG1 . THR A 1 363 ? 218.500 209.091 199.333 1.00 93.39  ? 363 THR A OG1 1 
ATOM   1115 C CG2 . THR A 1 363 ? 220.395 210.352 198.528 1.00 91.41  ? 363 THR A CG2 1 
ATOM   1116 N N   . LYS A 1 364 ? 219.352 208.741 202.874 1.00 95.73  ? 364 LYS A N   1 
ATOM   1117 C CA  . LYS A 1 364 ? 218.699 207.906 203.883 1.00 98.14  ? 364 LYS A CA  1 
ATOM   1118 C C   . LYS A 1 364 ? 217.180 208.071 203.804 1.00 98.79  ? 364 LYS A C   1 
ATOM   1119 O O   . LYS A 1 364 ? 216.524 208.605 204.700 1.00 97.88  ? 364 LYS A O   1 
ATOM   1120 C CB  . LYS A 1 364 ? 219.229 208.246 205.270 1.00 97.11  ? 364 LYS A CB  1 
ATOM   1121 C CG  . LYS A 1 364 ? 220.680 208.702 205.276 1.00 96.62  ? 364 LYS A CG  1 
ATOM   1122 C CD  . LYS A 1 364 ? 221.095 209.231 206.639 1.00 97.85  ? 364 LYS A CD  1 
ATOM   1123 C CE  . LYS A 1 364 ? 220.816 208.217 207.736 1.00 95.12  ? 364 LYS A CE  1 
ATOM   1124 N NZ  . LYS A 1 364 ? 220.944 208.815 209.093 1.00 94.20  ? 364 LYS A NZ  1 
ATOM   1125 N N   . THR A 1 365 ? 216.620 207.591 202.693 1.00 92.77  ? 365 THR A N   1 
ATOM   1126 C CA  . THR A 1 365 ? 215.177 207.637 202.478 1.00 92.70  ? 365 THR A CA  1 
ATOM   1127 C C   . THR A 1 365 ? 214.558 206.248 202.390 1.00 90.60  ? 365 THR A C   1 
ATOM   1128 O O   . THR A 1 365 ? 213.617 205.953 203.135 1.00 89.14  ? 365 THR A O   1 
ATOM   1129 C CB  . THR A 1 365 ? 214.851 208.443 201.213 1.00 92.62  ? 365 THR A CB  1 
ATOM   1130 O OG1 . THR A 1 365 ? 214.859 207.575 200.072 1.00 86.05  ? 365 THR A OG1 1 
ATOM   1131 C CG2 . THR A 1 365 ? 215.859 209.563 201.010 1.00 90.62  ? 365 THR A CG2 1 
ATOM   1132 N N   . PHE A 1 366 ? 215.053 205.384 201.507 1.00 81.34  ? 366 PHE A N   1 
ATOM   1133 C CA  . PHE A 1 366 ? 214.415 204.100 201.216 1.00 81.19  ? 366 PHE A CA  1 
ATOM   1134 C C   . PHE A 1 366 ? 215.177 202.987 201.930 1.00 83.49  ? 366 PHE A C   1 
ATOM   1135 O O   . PHE A 1 366 ? 216.168 202.463 201.420 1.00 82.62  ? 366 PHE A O   1 
ATOM   1136 C CB  . PHE A 1 366 ? 214.362 203.861 199.712 1.00 77.95  ? 366 PHE A CB  1 
ATOM   1137 C CG  . PHE A 1 366 ? 213.302 204.656 199.008 1.00 81.76  ? 366 PHE A CG  1 
ATOM   1138 C CD1 . PHE A 1 366 ? 212.189 205.114 199.693 1.00 82.44  ? 366 PHE A CD1 1 
ATOM   1139 C CD2 . PHE A 1 366 ? 213.419 204.948 197.659 1.00 83.83  ? 366 PHE A CD2 1 
ATOM   1140 C CE1 . PHE A 1 366 ? 211.213 205.846 199.046 1.00 80.97  ? 366 PHE A CE1 1 
ATOM   1141 C CE2 . PHE A 1 366 ? 212.446 205.680 197.006 1.00 79.87  ? 366 PHE A CE2 1 
ATOM   1142 C CZ  . PHE A 1 366 ? 211.342 206.130 197.701 1.00 77.43  ? 366 PHE A CZ  1 
ATOM   1143 N N   . TYR A 1 367 ? 214.692 202.618 203.117 1.00 80.61  ? 367 TYR A N   1 
ATOM   1144 C CA  . TYR A 1 367 ? 215.249 201.514 203.902 1.00 78.09  ? 367 TYR A CA  1 
ATOM   1145 C C   . TYR A 1 367 ? 216.757 201.669 204.081 1.00 74.50  ? 367 TYR A C   1 
ATOM   1146 O O   . TYR A 1 367 ? 217.541 200.770 203.772 1.00 76.79  ? 367 TYR A O   1 
ATOM   1147 C CB  . TYR A 1 367 ? 214.914 200.162 203.268 1.00 76.80  ? 367 TYR A CB  1 
ATOM   1148 C CG  . TYR A 1 367 ? 213.485 200.021 202.794 1.00 73.49  ? 367 TYR A CG  1 
ATOM   1149 C CD1 . TYR A 1 367 ? 212.493 199.561 203.649 1.00 72.68  ? 367 TYR A CD1 1 
ATOM   1150 C CD2 . TYR A 1 367 ? 213.132 200.330 201.487 1.00 72.47  ? 367 TYR A CD2 1 
ATOM   1151 C CE1 . TYR A 1 367 ? 211.187 199.425 203.219 1.00 76.92  ? 367 TYR A CE1 1 
ATOM   1152 C CE2 . TYR A 1 367 ? 211.830 200.197 201.049 1.00 74.99  ? 367 TYR A CE2 1 
ATOM   1153 C CZ  . TYR A 1 367 ? 210.862 199.744 201.918 1.00 78.26  ? 367 TYR A CZ  1 
ATOM   1154 O OH  . TYR A 1 367 ? 209.563 199.611 201.484 1.00 77.91  ? 367 TYR A OH  1 
ATOM   1155 N N   . TYR A 1 368 ? 217.164 202.837 204.585 1.00 78.21  ? 368 TYR A N   1 
ATOM   1156 C CA  . TYR A 1 368 ? 218.588 203.147 204.664 1.00 76.91  ? 368 TYR A CA  1 
ATOM   1157 C C   . TYR A 1 368 ? 219.326 202.182 205.583 1.00 81.98  ? 368 TYR A C   1 
ATOM   1158 O O   . TYR A 1 368 ? 220.426 201.727 205.254 1.00 85.67  ? 368 TYR A O   1 
ATOM   1159 C CB  . TYR A 1 368 ? 218.789 204.595 205.114 1.00 79.55  ? 368 TYR A CB  1 
ATOM   1160 C CG  . TYR A 1 368 ? 218.371 204.888 206.537 1.00 79.96  ? 368 TYR A CG  1 
ATOM   1161 C CD1 . TYR A 1 368 ? 217.032 205.042 206.870 1.00 82.80  ? 368 TYR A CD1 1 
ATOM   1162 C CD2 . TYR A 1 368 ? 219.316 205.028 207.543 1.00 79.00  ? 368 TYR A CD2 1 
ATOM   1163 C CE1 . TYR A 1 368 ? 216.646 205.317 208.168 1.00 85.50  ? 368 TYR A CE1 1 
ATOM   1164 C CE2 . TYR A 1 368 ? 218.940 205.305 208.843 1.00 79.23  ? 368 TYR A CE2 1 
ATOM   1165 C CZ  . TYR A 1 368 ? 217.604 205.446 209.150 1.00 84.13  ? 368 TYR A CZ  1 
ATOM   1166 O OH  . TYR A 1 368 ? 217.224 205.720 210.443 1.00 85.34  ? 368 TYR A OH  1 
ATOM   1167 N N   . LYS A 1 369 ? 218.737 201.846 206.733 1.00 83.65  ? 369 LYS A N   1 
ATOM   1168 C CA  . LYS A 1 369 ? 219.369 200.880 207.628 1.00 86.23  ? 369 LYS A CA  1 
ATOM   1169 C C   . LYS A 1 369 ? 219.524 199.528 206.944 1.00 83.34  ? 369 LYS A C   1 
ATOM   1170 O O   . LYS A 1 369 ? 220.618 198.948 206.918 1.00 80.87  ? 369 LYS A O   1 
ATOM   1171 C CB  . LYS A 1 369 ? 218.548 200.739 208.910 1.00 83.11  ? 369 LYS A CB  1 
ATOM   1172 C CG  . LYS A 1 369 ? 218.534 201.974 209.791 1.00 83.67  ? 369 LYS A CG  1 
ATOM   1173 C CD  . LYS A 1 369 ? 219.891 202.219 210.427 1.00 86.01  ? 369 LYS A CD  1 
ATOM   1174 C CE  . LYS A 1 369 ? 219.771 203.135 211.633 1.00 85.02  ? 369 LYS A CE  1 
ATOM   1175 N NZ  . LYS A 1 369 ? 218.688 202.694 212.556 1.00 85.76  ? 369 LYS A NZ  1 
ATOM   1176 N N   . SER A 1 370 ? 218.432 199.018 206.373 1.00 76.26  ? 370 SER A N   1 
ATOM   1177 C CA  . SER A 1 370 ? 218.463 197.721 205.706 1.00 75.63  ? 370 SER A CA  1 
ATOM   1178 C C   . SER A 1 370 ? 219.399 197.732 204.504 1.00 75.50  ? 370 SER A C   1 
ATOM   1179 O O   . SER A 1 370 ? 220.180 196.793 204.308 1.00 78.54  ? 370 SER A O   1 
ATOM   1180 C CB  . SER A 1 370 ? 217.048 197.332 205.285 1.00 78.06  ? 370 SER A CB  1 
ATOM   1181 O OG  . SER A 1 370 ? 217.062 196.519 204.129 1.00 77.02  ? 370 SER A OG  1 
ATOM   1182 N N   . ARG A 1 371 ? 219.333 198.786 203.688 1.00 83.46  ? 371 ARG A N   1 
ATOM   1183 C CA  . ARG A 1 371 ? 220.183 198.860 202.504 1.00 82.78  ? 371 ARG A CA  1 
ATOM   1184 C C   . ARG A 1 371 ? 221.658 198.929 202.880 1.00 83.73  ? 371 ARG A C   1 
ATOM   1185 O O   . ARG A 1 371 ? 222.497 198.273 202.252 1.00 86.00  ? 371 ARG A O   1 
ATOM   1186 C CB  . ARG A 1 371 ? 219.785 200.065 201.653 1.00 80.24  ? 371 ARG A CB  1 
ATOM   1187 C CG  . ARG A 1 371 ? 220.500 200.151 200.321 1.00 81.42  ? 371 ARG A CG  1 
ATOM   1188 C CD  . ARG A 1 371 ? 220.602 201.592 199.849 1.00 84.34  ? 371 ARG A CD  1 
ATOM   1189 N NE  . ARG A 1 371 ? 219.353 202.320 200.041 1.00 81.95  ? 371 ARG A NE  1 
ATOM   1190 C CZ  . ARG A 1 371 ? 219.225 203.408 200.788 1.00 84.74  ? 371 ARG A CZ  1 
ATOM   1191 N NH1 . ARG A 1 371 ? 220.254 203.925 201.437 1.00 87.04  ? 371 ARG A NH1 1 
ATOM   1192 N NH2 . ARG A 1 371 ? 218.034 203.991 200.885 1.00 86.33  ? 371 ARG A NH2 1 
ATOM   1193 N N   . PHE A 1 372 ? 221.996 199.717 203.903 1.00 79.77  ? 372 PHE A N   1 
ATOM   1194 C CA  . PHE A 1 372 ? 223.389 199.816 204.323 1.00 80.58  ? 372 PHE A CA  1 
ATOM   1195 C C   . PHE A 1 372 ? 223.881 198.505 204.923 1.00 84.11  ? 372 PHE A C   1 
ATOM   1196 O O   . PHE A 1 372 ? 225.031 198.110 204.699 1.00 83.21  ? 372 PHE A O   1 
ATOM   1197 C CB  . PHE A 1 372 ? 223.563 200.965 205.315 1.00 83.59  ? 372 PHE A CB  1 
ATOM   1198 C CG  . PHE A 1 372 ? 223.364 202.323 204.706 1.00 87.36  ? 372 PHE A CG  1 
ATOM   1199 C CD1 . PHE A 1 372 ? 223.558 202.521 203.350 1.00 85.33  ? 372 PHE A CD1 1 
ATOM   1200 C CD2 . PHE A 1 372 ? 222.993 203.402 205.490 1.00 84.41  ? 372 PHE A CD2 1 
ATOM   1201 C CE1 . PHE A 1 372 ? 223.377 203.768 202.785 1.00 86.28  ? 372 PHE A CE1 1 
ATOM   1202 C CE2 . PHE A 1 372 ? 222.811 204.651 204.931 1.00 84.27  ? 372 PHE A CE2 1 
ATOM   1203 C CZ  . PHE A 1 372 ? 223.003 204.835 203.577 1.00 87.77  ? 372 PHE A CZ  1 
ATOM   1204 N N   . TRP A 1 373 ? 223.031 197.819 205.694 1.00 79.08  ? 373 TRP A N   1 
ATOM   1205 C CA  . TRP A 1 373 ? 223.426 196.522 206.232 1.00 75.29  ? 373 TRP A CA  1 
ATOM   1206 C C   . TRP A 1 373 ? 223.653 195.517 205.109 1.00 74.87  ? 373 TRP A C   1 
ATOM   1207 O O   . TRP A 1 373 ? 224.620 194.744 205.144 1.00 74.77  ? 373 TRP A O   1 
ATOM   1208 C CB  . TRP A 1 373 ? 222.378 196.046 207.247 1.00 69.23  ? 373 TRP A CB  1 
ATOM   1209 C CG  . TRP A 1 373 ? 222.448 194.601 207.688 1.00 69.68  ? 373 TRP A CG  1 
ATOM   1210 C CD1 . TRP A 1 373 ? 222.813 194.154 208.925 1.00 76.27  ? 373 TRP A CD1 1 
ATOM   1211 C CD2 . TRP A 1 373 ? 222.009 193.439 206.963 1.00 73.28  ? 373 TRP A CD2 1 
ATOM   1212 N NE1 . TRP A 1 373 ? 222.711 192.788 208.989 1.00 79.71  ? 373 TRP A NE1 1 
ATOM   1213 C CE2 . TRP A 1 373 ? 222.211 192.324 207.802 1.00 78.26  ? 373 TRP A CE2 1 
ATOM   1214 C CE3 . TRP A 1 373 ? 221.496 193.230 205.681 1.00 75.14  ? 373 TRP A CE3 1 
ATOM   1215 C CZ2 . TRP A 1 373 ? 221.920 191.023 207.398 1.00 75.83  ? 373 TRP A CZ2 1 
ATOM   1216 C CZ3 . TRP A 1 373 ? 221.213 191.937 205.281 1.00 78.16  ? 373 TRP A CZ3 1 
ATOM   1217 C CH2 . TRP A 1 373 ? 221.423 190.851 206.137 1.00 74.69  ? 373 TRP A CH2 1 
ATOM   1218 N N   . LEU A 1 374 ? 222.796 195.543 204.083 1.00 72.29  ? 374 LEU A N   1 
ATOM   1219 C CA  . LEU A 1 374 ? 222.996 194.664 202.936 1.00 64.37  ? 374 LEU A CA  1 
ATOM   1220 C C   . LEU A 1 374 ? 224.288 194.996 202.202 1.00 65.86  ? 374 LEU A C   1 
ATOM   1221 O O   . LEU A 1 374 ? 225.009 194.091 201.777 1.00 72.63  ? 374 LEU A O   1 
ATOM   1222 C CB  . LEU A 1 374 ? 221.808 194.748 201.979 1.00 64.54  ? 374 LEU A CB  1 
ATOM   1223 C CG  . LEU A 1 374 ? 221.877 193.714 200.852 1.00 63.92  ? 374 LEU A CG  1 
ATOM   1224 C CD1 . LEU A 1 374 ? 221.784 192.307 201.420 1.00 63.20  ? 374 LEU A CD1 1 
ATOM   1225 C CD2 . LEU A 1 374 ? 220.809 193.945 199.795 1.00 71.39  ? 374 LEU A CD2 1 
ATOM   1226 N N   . LEU A 1 375 ? 224.593 196.283 202.032 1.00 67.27  ? 375 LEU A N   1 
ATOM   1227 C CA  . LEU A 1 375 ? 225.825 196.668 201.348 1.00 70.42  ? 375 LEU A CA  1 
ATOM   1228 C C   . LEU A 1 375 ? 227.056 196.224 202.131 1.00 78.31  ? 375 LEU A C   1 
ATOM   1229 O O   . LEU A 1 375 ? 228.011 195.684 201.557 1.00 78.99  ? 375 LEU A O   1 
ATOM   1230 C CB  . LEU A 1 375 ? 225.847 198.180 201.123 1.00 73.47  ? 375 LEU A CB  1 
ATOM   1231 C CG  . LEU A 1 375 ? 224.995 198.721 199.975 1.00 78.27  ? 375 LEU A CG  1 
ATOM   1232 C CD1 . LEU A 1 375 ? 225.524 200.069 199.517 1.00 80.26  ? 375 LEU A CD1 1 
ATOM   1233 C CD2 . LEU A 1 375 ? 224.969 197.737 198.817 1.00 75.84  ? 375 LEU A CD2 1 
ATOM   1234 N N   . LYS A 1 376 ? 227.049 196.445 203.449 1.00 79.53  ? 376 LYS A N   1 
ATOM   1235 C CA  . LYS A 1 376 ? 228.178 196.033 204.275 1.00 77.29  ? 376 LYS A CA  1 
ATOM   1236 C C   . LYS A 1 376 ? 228.369 194.524 204.228 1.00 74.26  ? 376 LYS A C   1 
ATOM   1237 O O   . LYS A 1 376 ? 229.500 194.033 204.110 1.00 72.29  ? 376 LYS A O   1 
ATOM   1238 C CB  . LYS A 1 376 ? 227.973 196.499 205.717 1.00 74.57  ? 376 LYS A CB  1 
ATOM   1239 C CG  . LYS A 1 376 ? 228.727 197.766 206.080 1.00 76.67  ? 376 LYS A CG  1 
ATOM   1240 C CD  . LYS A 1 376 ? 227.826 198.986 205.986 1.00 76.24  ? 376 LYS A CD  1 
ATOM   1241 C CE  . LYS A 1 376 ? 228.568 200.256 206.362 1.00 76.34  ? 376 LYS A CE  1 
ATOM   1242 N NZ  . LYS A 1 376 ? 227.929 201.461 205.765 1.00 72.67  ? 376 LYS A NZ  1 
ATOM   1243 N N   . LEU A 1 377 ? 227.273 193.770 204.297 1.00 66.80  ? 377 LEU A N   1 
ATOM   1244 C CA  . LEU A 1 377 ? 227.392 192.320 204.277 1.00 63.27  ? 377 LEU A CA  1 
ATOM   1245 C C   . LEU A 1 377 ? 227.760 191.799 202.890 1.00 65.53  ? 377 LEU A C   1 
ATOM   1246 O O   . LEU A 1 377 ? 228.455 190.786 202.787 1.00 68.90  ? 377 LEU A O   1 
ATOM   1247 C CB  . LEU A 1 377 ? 226.098 191.701 204.811 1.00 62.14  ? 377 LEU A CB  1 
ATOM   1248 C CG  . LEU A 1 377 ? 225.723 190.240 204.598 1.00 62.69  ? 377 LEU A CG  1 
ATOM   1249 C CD1 . LEU A 1 377 ? 224.817 189.814 205.718 1.00 65.98  ? 377 LEU A CD1 1 
ATOM   1250 C CD2 . LEU A 1 377 ? 224.977 190.102 203.306 1.00 62.76  ? 377 LEU A CD2 1 
ATOM   1251 N N   . LEU A 1 378 ? 227.339 192.485 201.823 1.00 64.56  ? 378 LEU A N   1 
ATOM   1252 C CA  . LEU A 1 378 ? 227.815 192.151 200.483 1.00 63.42  ? 378 LEU A CA  1 
ATOM   1253 C C   . LEU A 1 378 ? 229.322 192.330 200.385 1.00 70.00  ? 378 LEU A C   1 
ATOM   1254 O O   . LEU A 1 378 ? 230.035 191.465 199.859 1.00 72.41  ? 378 LEU A O   1 
ATOM   1255 C CB  . LEU A 1 378 ? 227.121 193.030 199.440 1.00 64.54  ? 378 LEU A CB  1 
ATOM   1256 C CG  . LEU A 1 378 ? 226.006 192.476 198.549 1.00 67.13  ? 378 LEU A CG  1 
ATOM   1257 C CD1 . LEU A 1 378 ? 226.534 191.390 197.618 1.00 68.04  ? 378 LEU A CD1 1 
ATOM   1258 C CD2 . LEU A 1 378 ? 224.825 191.987 199.362 1.00 68.84  ? 378 LEU A CD2 1 
ATOM   1259 N N   . PHE A 1 379 ? 229.824 193.462 200.887 1.00 78.21  ? 379 PHE A N   1 
ATOM   1260 C CA  . PHE A 1 379 ? 231.261 193.709 200.867 1.00 80.24  ? 379 PHE A CA  1 
ATOM   1261 C C   . PHE A 1 379 ? 232.009 192.650 201.664 1.00 79.67  ? 379 PHE A C   1 
ATOM   1262 O O   . PHE A 1 379 ? 233.060 192.163 201.232 1.00 77.87  ? 379 PHE A O   1 
ATOM   1263 C CB  . PHE A 1 379 ? 231.562 195.104 201.415 1.00 81.06  ? 379 PHE A CB  1 
ATOM   1264 C CG  . PHE A 1 379 ? 233.019 195.347 201.690 1.00 83.19  ? 379 PHE A CG  1 
ATOM   1265 C CD1 . PHE A 1 379 ? 233.969 195.158 200.700 1.00 81.10  ? 379 PHE A CD1 1 
ATOM   1266 C CD2 . PHE A 1 379 ? 233.439 195.759 202.944 1.00 81.45  ? 379 PHE A CD2 1 
ATOM   1267 C CE1 . PHE A 1 379 ? 235.309 195.377 200.955 1.00 80.38  ? 379 PHE A CE1 1 
ATOM   1268 C CE2 . PHE A 1 379 ? 234.777 195.982 203.204 1.00 81.04  ? 379 PHE A CE2 1 
ATOM   1269 C CZ  . PHE A 1 379 ? 235.713 195.790 202.208 1.00 80.06  ? 379 PHE A CZ  1 
ATOM   1270 N N   . ARG A 1 380 ? 231.484 192.285 202.835 1.00 73.51  ? 380 ARG A N   1 
ATOM   1271 C CA  . ARG A 1 380 ? 232.129 191.253 203.640 1.00 70.60  ? 380 ARG A CA  1 
ATOM   1272 C C   . ARG A 1 380 ? 232.115 189.902 202.931 1.00 68.47  ? 380 ARG A C   1 
ATOM   1273 O O   . ARG A 1 380 ? 233.108 189.166 202.963 1.00 70.37  ? 380 ARG A O   1 
ATOM   1274 C CB  . ARG A 1 380 ? 231.447 191.152 205.003 1.00 67.30  ? 380 ARG A CB  1 
ATOM   1275 C CG  . ARG A 1 380 ? 231.997 190.050 205.889 1.00 68.02  ? 380 ARG A CG  1 
ATOM   1276 C CD  . ARG A 1 380 ? 232.033 190.445 207.365 1.00 69.44  ? 380 ARG A CD  1 
ATOM   1277 N NE  . ARG A 1 380 ? 230.708 190.678 207.931 1.00 70.02  ? 380 ARG A NE  1 
ATOM   1278 C CZ  . ARG A 1 380 ? 230.103 191.857 207.984 1.00 70.16  ? 380 ARG A CZ  1 
ATOM   1279 N NH1 . ARG A 1 380 ? 230.689 192.956 207.538 1.00 71.67  ? 380 ARG A NH1 1 
ATOM   1280 N NH2 . ARG A 1 380 ? 228.883 191.937 208.507 1.00 72.63  ? 380 ARG A NH2 1 
ATOM   1281 N N   . VAL A 1 381 ? 230.999 189.560 202.283 1.00 65.07  ? 381 VAL A N   1 
ATOM   1282 C CA  . VAL A 1 381 ? 230.863 188.246 201.662 1.00 65.00  ? 381 VAL A CA  1 
ATOM   1283 C C   . VAL A 1 381 ? 231.786 188.120 200.456 1.00 61.92  ? 381 VAL A C   1 
ATOM   1284 O O   . VAL A 1 381 ? 232.486 187.113 200.295 1.00 68.67  ? 381 VAL A O   1 
ATOM   1285 C CB  . VAL A 1 381 ? 229.394 187.983 201.283 1.00 65.11  ? 381 VAL A CB  1 
ATOM   1286 C CG1 . VAL A 1 381 ? 229.301 186.984 200.138 1.00 59.83  ? 381 VAL A CG1 1 
ATOM   1287 C CG2 . VAL A 1 381 ? 228.617 187.486 202.489 1.00 68.33  ? 381 VAL A CG2 1 
ATOM   1288 N N   . PHE A 1 382 ? 231.807 189.138 199.588 1.00 65.09  ? 382 PHE A N   1 
ATOM   1289 C CA  . PHE A 1 382 ? 232.619 189.035 198.378 1.00 70.08  ? 382 PHE A CA  1 
ATOM   1290 C C   . PHE A 1 382 ? 234.108 188.991 198.692 1.00 75.26  ? 382 PHE A C   1 
ATOM   1291 O O   . PHE A 1 382 ? 234.871 188.335 197.975 1.00 72.49  ? 382 PHE A O   1 
ATOM   1292 C CB  . PHE A 1 382 ? 232.303 190.185 197.424 1.00 75.01  ? 382 PHE A CB  1 
ATOM   1293 C CG  . PHE A 1 382 ? 231.273 189.840 196.390 1.00 71.48  ? 382 PHE A CG  1 
ATOM   1294 C CD1 . PHE A 1 382 ? 230.036 189.346 196.765 1.00 70.12  ? 382 PHE A CD1 1 
ATOM   1295 C CD2 . PHE A 1 382 ? 231.545 189.999 195.042 1.00 72.50  ? 382 PHE A CD2 1 
ATOM   1296 C CE1 . PHE A 1 382 ? 229.087 189.022 195.815 1.00 67.54  ? 382 PHE A CE1 1 
ATOM   1297 C CE2 . PHE A 1 382 ? 230.599 189.677 194.086 1.00 73.78  ? 382 PHE A CE2 1 
ATOM   1298 C CZ  . PHE A 1 382 ? 229.369 189.187 194.474 1.00 72.54  ? 382 PHE A CZ  1 
ATOM   1299 N N   . THR A 1 383 ? 234.540 189.669 199.749 1.00 86.21  ? 383 THR A N   1 
ATOM   1300 C CA  . THR A 1 383 ? 235.908 189.541 200.251 1.00 84.98  ? 383 THR A CA  1 
ATOM   1301 C C   . THR A 1 383 ? 235.949 188.538 201.402 1.00 82.71  ? 383 THR A C   1 
ATOM   1302 O O   . THR A 1 383 ? 236.188 188.871 202.562 1.00 82.60  ? 383 THR A O   1 
ATOM   1303 C CB  . THR A 1 383 ? 236.449 190.904 200.671 1.00 85.28  ? 383 THR A CB  1 
ATOM   1304 O OG1 . THR A 1 383 ? 235.847 191.300 201.908 1.00 84.25  ? 383 THR A OG1 1 
ATOM   1305 C CG2 . THR A 1 383 ? 236.143 191.948 199.605 1.00 80.54  ? 383 THR A CG2 1 
ATOM   1306 N N   . ALA A 1 384 ? 235.707 187.279 201.042 1.00 82.13  ? 384 ALA A N   1 
ATOM   1307 C CA  . ALA A 1 384 ? 235.484 186.183 201.979 1.00 85.04  ? 384 ALA A CA  1 
ATOM   1308 C C   . ALA A 1 384 ? 236.644 185.915 202.939 1.00 91.62  ? 384 ALA A C   1 
ATOM   1309 O O   . ALA A 1 384 ? 236.423 185.878 204.156 1.00 89.36  ? 384 ALA A O   1 
ATOM   1310 C CB  . ALA A 1 384 ? 235.159 184.906 201.201 1.00 83.24  ? 384 ALA A CB  1 
ATOM   1311 N N   . PRO A 1 385 ? 237.893 185.735 202.462 1.00 99.27  ? 385 PRO A N   1 
ATOM   1312 C CA  . PRO A 1 385 ? 238.921 185.171 203.348 1.00 93.38  ? 385 PRO A CA  1 
ATOM   1313 C C   . PRO A 1 385 ? 239.540 186.170 204.313 1.00 92.87  ? 385 PRO A C   1 
ATOM   1314 O O   . PRO A 1 385 ? 240.609 185.903 204.871 1.00 91.57  ? 385 PRO A O   1 
ATOM   1315 C CB  . PRO A 1 385 ? 239.965 184.645 202.359 1.00 89.19  ? 385 PRO A CB  1 
ATOM   1316 C CG  . PRO A 1 385 ? 239.906 185.626 201.250 1.00 91.06  ? 385 PRO A CG  1 
ATOM   1317 C CD  . PRO A 1 385 ? 238.451 186.027 201.125 1.00 93.45  ? 385 PRO A CD  1 
ATOM   1318 N N   . PHE A 1 386 ? 238.894 187.315 204.525 1.00 96.58  ? 386 PHE A N   1 
ATOM   1319 C CA  . PHE A 1 386 ? 239.463 188.361 205.362 1.00 97.48  ? 386 PHE A CA  1 
ATOM   1320 C C   . PHE A 1 386 ? 238.647 188.677 206.611 1.00 99.47  ? 386 PHE A C   1 
ATOM   1321 O O   . PHE A 1 386 ? 239.112 189.461 207.447 1.00 100.19 ? 386 PHE A O   1 
ATOM   1322 C CB  . PHE A 1 386 ? 239.666 189.639 204.536 1.00 96.73  ? 386 PHE A CB  1 
ATOM   1323 C CG  . PHE A 1 386 ? 240.253 189.389 203.173 1.00 98.01  ? 386 PHE A CG  1 
ATOM   1324 C CD1 . PHE A 1 386 ? 241.446 188.697 203.036 1.00 97.10  ? 386 PHE A CD1 1 
ATOM   1325 C CD2 . PHE A 1 386 ? 239.614 189.842 202.031 1.00 95.56  ? 386 PHE A CD2 1 
ATOM   1326 C CE1 . PHE A 1 386 ? 241.990 188.463 201.787 1.00 95.95  ? 386 PHE A CE1 1 
ATOM   1327 C CE2 . PHE A 1 386 ? 240.154 189.610 200.778 1.00 92.37  ? 386 PHE A CE2 1 
ATOM   1328 C CZ  . PHE A 1 386 ? 241.343 188.920 200.656 1.00 93.20  ? 386 PHE A CZ  1 
ATOM   1329 N N   . HIS A 1 387 ? 237.458 188.098 206.771 1.00 94.66  ? 387 HIS A N   1 
ATOM   1330 C CA  . HIS A 1 387 ? 236.667 188.290 207.980 1.00 91.88  ? 387 HIS A CA  1 
ATOM   1331 C C   . HIS A 1 387 ? 236.003 186.983 208.386 1.00 92.25  ? 387 HIS A C   1 
ATOM   1332 O O   . HIS A 1 387 ? 235.803 186.085 207.564 1.00 93.01  ? 387 HIS A O   1 
ATOM   1333 C CB  . HIS A 1 387 ? 235.597 189.380 207.812 1.00 88.78  ? 387 HIS A CB  1 
ATOM   1334 C CG  . HIS A 1 387 ? 235.983 190.469 206.862 1.00 91.45  ? 387 HIS A CG  1 
ATOM   1335 N ND1 . HIS A 1 387 ? 236.639 191.612 207.263 1.00 92.27  ? 387 HIS A ND1 1 
ATOM   1336 C CD2 . HIS A 1 387 ? 235.810 190.584 205.524 1.00 92.64  ? 387 HIS A CD2 1 
ATOM   1337 C CE1 . HIS A 1 387 ? 236.850 192.387 206.214 1.00 94.57  ? 387 HIS A CE1 1 
ATOM   1338 N NE2 . HIS A 1 387 ? 236.356 191.786 205.147 1.00 94.65  ? 387 HIS A NE2 1 
ATOM   1339 N N   . LYS A 1 388 ? 235.667 186.892 209.671 1.00 84.64  ? 388 LYS A N   1 
ATOM   1340 C CA  . LYS A 1 388 ? 235.035 185.698 210.213 1.00 83.71  ? 388 LYS A CA  1 
ATOM   1341 C C   . LYS A 1 388 ? 233.669 185.481 209.573 1.00 84.77  ? 388 LYS A C   1 
ATOM   1342 O O   . LYS A 1 388 ? 232.930 186.433 209.307 1.00 84.45  ? 388 LYS A O   1 
ATOM   1343 C CB  . LYS A 1 388 ? 234.895 185.823 211.731 1.00 84.29  ? 388 LYS A CB  1 
ATOM   1344 C CG  . LYS A 1 388 ? 234.266 184.622 212.419 1.00 84.81  ? 388 LYS A CG  1 
ATOM   1345 C CD  . LYS A 1 388 ? 234.129 184.857 213.917 1.00 85.14  ? 388 LYS A CD  1 
ATOM   1346 C CE  . LYS A 1 388 ? 235.436 185.335 214.534 1.00 87.55  ? 388 LYS A CE  1 
ATOM   1347 N NZ  . LYS A 1 388 ? 236.565 184.397 214.286 1.00 88.66  ? 388 LYS A NZ  1 
ATOM   1348 N N   . VAL A 1 389 ? 233.337 184.216 209.323 1.00 70.21  ? 389 VAL A N   1 
ATOM   1349 C CA  . VAL A 1 389 ? 232.093 183.860 208.649 1.00 69.80  ? 389 VAL A CA  1 
ATOM   1350 C C   . VAL A 1 389 ? 230.965 183.726 209.663 1.00 68.53  ? 389 VAL A C   1 
ATOM   1351 O O   . VAL A 1 389 ? 230.821 182.687 210.316 1.00 66.36  ? 389 VAL A O   1 
ATOM   1352 C CB  . VAL A 1 389 ? 232.257 182.562 207.837 1.00 70.34  ? 389 VAL A CB  1 
ATOM   1353 C CG1 . VAL A 1 389 ? 230.976 182.242 207.085 1.00 69.82  ? 389 VAL A CG1 1 
ATOM   1354 C CG2 . VAL A 1 389 ? 233.428 182.684 206.877 1.00 71.57  ? 389 VAL A CG2 1 
ATOM   1355 N N   . GLY A 1 390 ? 230.163 184.776 209.805 1.00 62.93  ? 390 GLY A N   1 
ATOM   1356 C CA  . GLY A 1 390 ? 228.961 184.706 210.605 1.00 62.51  ? 390 GLY A CA  1 
ATOM   1357 C C   . GLY A 1 390 ? 227.856 183.972 209.867 1.00 60.59  ? 390 GLY A C   1 
ATOM   1358 O O   . GLY A 1 390 ? 227.996 183.555 208.717 1.00 65.81  ? 390 GLY A O   1 
ATOM   1359 N N   . PHE A 1 391 ? 226.726 183.805 210.558 1.00 48.60  ? 391 PHE A N   1 
ATOM   1360 C CA  . PHE A 1 391 ? 225.606 183.092 209.951 1.00 48.96  ? 391 PHE A CA  1 
ATOM   1361 C C   . PHE A 1 391 ? 225.062 183.843 208.745 1.00 44.31  ? 391 PHE A C   1 
ATOM   1362 O O   . PHE A 1 391 ? 224.703 183.228 207.736 1.00 56.12  ? 391 PHE A O   1 
ATOM   1363 C CB  . PHE A 1 391 ? 224.492 182.860 210.971 1.00 54.08  ? 391 PHE A CB  1 
ATOM   1364 C CG  . PHE A 1 391 ? 223.321 182.092 210.417 1.00 50.77  ? 391 PHE A CG  1 
ATOM   1365 C CD1 . PHE A 1 391 ? 222.262 182.750 209.811 1.00 44.75  ? 391 PHE A CD1 1 
ATOM   1366 C CD2 . PHE A 1 391 ? 223.287 180.711 210.491 1.00 50.66  ? 391 PHE A CD2 1 
ATOM   1367 C CE1 . PHE A 1 391 ? 221.192 182.044 209.296 1.00 41.91  ? 391 PHE A CE1 1 
ATOM   1368 C CE2 . PHE A 1 391 ? 222.218 180.001 209.979 1.00 43.12  ? 391 PHE A CE2 1 
ATOM   1369 C CZ  . PHE A 1 391 ? 221.171 180.669 209.381 1.00 43.83  ? 391 PHE A CZ  1 
ATOM   1370 N N   . ALA A 1 392 ? 224.971 185.170 208.838 1.00 36.58  ? 392 ALA A N   1 
ATOM   1371 C CA  . ALA A 1 392 ? 224.409 185.953 207.743 1.00 42.12  ? 392 ALA A CA  1 
ATOM   1372 C C   . ALA A 1 392 ? 225.283 185.879 206.496 1.00 48.45  ? 392 ALA A C   1 
ATOM   1373 O O   . ALA A 1 392 ? 224.769 185.827 205.371 1.00 42.18  ? 392 ALA A O   1 
ATOM   1374 C CB  . ALA A 1 392 ? 224.215 187.400 208.190 1.00 42.97  ? 392 ALA A CB  1 
ATOM   1375 N N   . ASP A 1 393 ? 226.606 185.880 206.675 1.00 61.80  ? 393 ASP A N   1 
ATOM   1376 C CA  . ASP A 1 393 ? 227.512 185.820 205.532 1.00 58.04  ? 393 ASP A CA  1 
ATOM   1377 C C   . ASP A 1 393 ? 227.385 184.487 204.804 1.00 48.49  ? 393 ASP A C   1 
ATOM   1378 O O   . ASP A 1 393 ? 227.237 184.446 203.577 1.00 55.44  ? 393 ASP A O   1 
ATOM   1379 C CB  . ASP A 1 393 ? 228.948 186.041 206.003 1.00 59.84  ? 393 ASP A CB  1 
ATOM   1380 C CG  . ASP A 1 393 ? 229.051 187.125 207.057 1.00 63.22  ? 393 ASP A CG  1 
ATOM   1381 O OD1 . ASP A 1 393 ? 228.446 186.961 208.137 1.00 57.57  ? 393 ASP A OD1 1 
ATOM   1382 O OD2 . ASP A 1 393 ? 229.727 188.141 206.806 1.00 64.63  ? 393 ASP A OD2 1 
ATOM   1383 N N   . PHE A 1 394 ? 227.447 183.385 205.555 1.00 27.56  ? 394 PHE A N   1 
ATOM   1384 C CA  . PHE A 1 394 ? 227.180 182.063 204.997 1.00 31.35  ? 394 PHE A CA  1 
ATOM   1385 C C   . PHE A 1 394 ? 225.824 182.019 204.308 1.00 39.00  ? 394 PHE A C   1 
ATOM   1386 O O   . PHE A 1 394 ? 225.680 181.447 203.221 1.00 50.47  ? 394 PHE A O   1 
ATOM   1387 C CB  . PHE A 1 394 ? 227.244 181.016 206.111 1.00 37.10  ? 394 PHE A CB  1 
ATOM   1388 C CG  . PHE A 1 394 ? 226.363 179.823 205.873 1.00 44.46  ? 394 PHE A CG  1 
ATOM   1389 C CD1 . PHE A 1 394 ? 226.660 178.901 204.886 1.00 57.56  ? 394 PHE A CD1 1 
ATOM   1390 C CD2 . PHE A 1 394 ? 225.224 179.635 206.636 1.00 35.49  ? 394 PHE A CD2 1 
ATOM   1391 C CE1 . PHE A 1 394 ? 225.841 177.809 204.669 1.00 51.72  ? 394 PHE A CE1 1 
ATOM   1392 C CE2 . PHE A 1 394 ? 224.402 178.548 206.423 1.00 34.37  ? 394 PHE A CE2 1 
ATOM   1393 C CZ  . PHE A 1 394 ? 224.711 177.633 205.440 1.00 41.18  ? 394 PHE A CZ  1 
ATOM   1394 N N   . TRP A 1 395 ? 224.816 182.618 204.939 1.00 42.61  ? 395 TRP A N   1 
ATOM   1395 C CA  . TRP A 1 395 ? 223.456 182.571 204.423 1.00 40.37  ? 395 TRP A CA  1 
ATOM   1396 C C   . TRP A 1 395 ? 223.369 183.236 203.054 1.00 49.00  ? 395 TRP A C   1 
ATOM   1397 O O   . TRP A 1 395 ? 222.879 182.640 202.088 1.00 54.11  ? 395 TRP A O   1 
ATOM   1398 C CB  . TRP A 1 395 ? 222.520 183.240 205.430 1.00 42.63  ? 395 TRP A CB  1 
ATOM   1399 C CG  . TRP A 1 395 ? 221.102 183.338 204.998 1.00 43.14  ? 395 TRP A CG  1 
ATOM   1400 C CD1 . TRP A 1 395 ? 220.124 182.407 205.182 1.00 41.25  ? 395 TRP A CD1 1 
ATOM   1401 C CD2 . TRP A 1 395 ? 220.488 184.439 204.321 1.00 50.22  ? 395 TRP A CD2 1 
ATOM   1402 N NE1 . TRP A 1 395 ? 218.940 182.858 204.656 1.00 55.24  ? 395 TRP A NE1 1 
ATOM   1403 C CE2 . TRP A 1 395 ? 219.137 184.103 204.121 1.00 48.98  ? 395 TRP A CE2 1 
ATOM   1404 C CE3 . TRP A 1 395 ? 220.952 185.674 203.862 1.00 49.59  ? 395 TRP A CE3 1 
ATOM   1405 C CZ2 . TRP A 1 395 ? 218.244 184.958 203.483 1.00 40.40  ? 395 TRP A CZ2 1 
ATOM   1406 C CZ3 . TRP A 1 395 ? 220.066 186.519 203.227 1.00 47.94  ? 395 TRP A CZ3 1 
ATOM   1407 C CH2 . TRP A 1 395 ? 218.728 186.157 203.041 1.00 46.13  ? 395 TRP A CH2 1 
ATOM   1408 N N   . LEU A 1 396 ? 223.878 184.466 202.944 1.00 51.33  ? 396 LEU A N   1 
ATOM   1409 C CA  . LEU A 1 396 ? 223.826 185.149 201.655 1.00 47.47  ? 396 LEU A CA  1 
ATOM   1410 C C   . LEU A 1 396 ? 224.727 184.486 200.622 1.00 48.05  ? 396 LEU A C   1 
ATOM   1411 O O   . LEU A 1 396 ? 224.386 184.465 199.435 1.00 48.66  ? 396 LEU A O   1 
ATOM   1412 C CB  . LEU A 1 396 ? 224.215 186.622 201.778 1.00 40.48  ? 396 LEU A CB  1 
ATOM   1413 C CG  . LEU A 1 396 ? 224.034 187.282 200.401 1.00 43.03  ? 396 LEU A CG  1 
ATOM   1414 C CD1 . LEU A 1 396 ? 222.555 187.346 200.017 1.00 44.38  ? 396 LEU A CD1 1 
ATOM   1415 C CD2 . LEU A 1 396 ? 224.709 188.622 200.249 1.00 47.44  ? 396 LEU A CD2 1 
ATOM   1416 N N   . ALA A 1 397 ? 225.880 183.956 201.035 1.00 41.45  ? 397 ALA A N   1 
ATOM   1417 C CA  . ALA A 1 397 ? 226.738 183.270 200.077 1.00 33.20  ? 397 ALA A CA  1 
ATOM   1418 C C   . ALA A 1 397 ? 226.041 182.042 199.505 1.00 39.45  ? 397 ALA A C   1 
ATOM   1419 O O   . ALA A 1 397 ? 226.146 181.760 198.306 1.00 54.06  ? 397 ALA A O   1 
ATOM   1420 C CB  . ALA A 1 397 ? 228.064 182.896 200.735 1.00 43.21  ? 397 ALA A CB  1 
ATOM   1421 N N   . ASP A 1 398 ? 225.304 181.311 200.342 1.00 31.70  ? 398 ASP A N   1 
ATOM   1422 C CA  . ASP A 1 398 ? 224.520 180.187 199.839 1.00 37.31  ? 398 ASP A CA  1 
ATOM   1423 C C   . ASP A 1 398 ? 223.387 180.664 198.934 1.00 44.74  ? 398 ASP A C   1 
ATOM   1424 O O   . ASP A 1 398 ? 223.080 180.025 197.919 1.00 49.19  ? 398 ASP A O   1 
ATOM   1425 C CB  . ASP A 1 398 ? 223.977 179.367 201.007 1.00 41.43  ? 398 ASP A CB  1 
ATOM   1426 C CG  . ASP A 1 398 ? 224.016 177.879 200.737 1.00 47.99  ? 398 ASP A CG  1 
ATOM   1427 O OD1 . ASP A 1 398 ? 224.302 177.492 199.585 1.00 49.30  ? 398 ASP A OD1 1 
ATOM   1428 O OD2 . ASP A 1 398 ? 223.763 177.095 201.675 1.00 49.63  ? 398 ASP A OD2 1 
ATOM   1429 N N   . GLN A 1 399 ? 222.751 181.786 199.288 1.00 38.95  ? 399 GLN A N   1 
ATOM   1430 C CA  . GLN A 1 399 ? 221.735 182.369 198.414 1.00 38.46  ? 399 GLN A CA  1 
ATOM   1431 C C   . GLN A 1 399 ? 222.307 182.660 197.033 1.00 41.96  ? 399 GLN A C   1 
ATOM   1432 O O   . GLN A 1 399 ? 221.693 182.339 196.009 1.00 41.89  ? 399 GLN A O   1 
ATOM   1433 C CB  . GLN A 1 399 ? 221.166 183.646 199.038 1.00 40.27  ? 399 GLN A CB  1 
ATOM   1434 C CG  . GLN A 1 399 ? 220.528 183.469 200.408 1.00 37.80  ? 399 GLN A CG  1 
ATOM   1435 C CD  . GLN A 1 399 ? 219.240 182.671 200.370 1.00 45.17  ? 399 GLN A CD  1 
ATOM   1436 O OE1 . GLN A 1 399 ? 218.868 182.117 199.342 1.00 53.66  ? 399 GLN A OE1 1 
ATOM   1437 N NE2 . GLN A 1 399 ? 218.564 182.590 201.505 1.00 40.78  ? 399 GLN A NE2 1 
ATOM   1438 N N   . LEU A 1 400 ? 223.493 183.268 196.990 1.00 39.30  ? 400 LEU A N   1 
ATOM   1439 C CA  . LEU A 1 400 ? 224.158 183.527 195.718 1.00 40.08  ? 400 LEU A CA  1 
ATOM   1440 C C   . LEU A 1 400 ? 224.490 182.225 195.001 1.00 43.96  ? 400 LEU A C   1 
ATOM   1441 O O   . LEU A 1 400 ? 224.386 182.140 193.771 1.00 53.34  ? 400 LEU A O   1 
ATOM   1442 C CB  . LEU A 1 400 ? 225.423 184.352 195.945 1.00 39.09  ? 400 LEU A CB  1 
ATOM   1443 C CG  . LEU A 1 400 ? 225.321 185.840 195.615 1.00 40.85  ? 400 LEU A CG  1 
ATOM   1444 C CD1 . LEU A 1 400 ? 224.429 186.552 196.619 1.00 42.72  ? 400 LEU A CD1 1 
ATOM   1445 C CD2 . LEU A 1 400 ? 226.701 186.469 195.578 1.00 36.71  ? 400 LEU A CD2 1 
ATOM   1446 N N   . ASN A 1 401 ? 224.903 181.204 195.755 1.00 49.71  ? 401 ASN A N   1 
ATOM   1447 C CA  . ASN A 1 401 ? 225.135 179.887 195.171 1.00 53.73  ? 401 ASN A CA  1 
ATOM   1448 C C   . ASN A 1 401 ? 223.881 179.366 194.484 1.00 45.47  ? 401 ASN A C   1 
ATOM   1449 O O   . ASN A 1 401 ? 223.962 178.662 193.471 1.00 50.57  ? 401 ASN A O   1 
ATOM   1450 C CB  . ASN A 1 401 ? 225.614 178.915 196.253 1.00 54.99  ? 401 ASN A CB  1 
ATOM   1451 C CG  . ASN A 1 401 ? 225.264 177.471 195.944 1.00 52.81  ? 401 ASN A CG  1 
ATOM   1452 O OD1 . ASN A 1 401 ? 224.164 177.006 196.245 1.00 52.84  ? 401 ASN A OD1 1 
ATOM   1453 N ND2 . ASN A 1 401 ? 226.204 176.752 195.342 1.00 52.23  ? 401 ASN A ND2 1 
ATOM   1454 N N   . SER A 1 402 ? 222.711 179.711 195.014 1.00 39.69  ? 402 SER A N   1 
ATOM   1455 C CA  . SER A 1 402 ? 221.450 179.378 194.363 1.00 48.45  ? 402 SER A CA  1 
ATOM   1456 C C   . SER A 1 402 ? 220.970 180.458 193.401 1.00 58.80  ? 402 SER A C   1 
ATOM   1457 O O   . SER A 1 402 ? 219.927 180.278 192.764 1.00 53.12  ? 402 SER A O   1 
ATOM   1458 C CB  . SER A 1 402 ? 220.366 179.112 195.407 1.00 45.64  ? 402 SER A CB  1 
ATOM   1459 O OG  . SER A 1 402 ? 220.425 177.775 195.869 1.00 55.43  ? 402 SER A OG  1 
ATOM   1460 N N   . LEU A 1 403 ? 221.696 181.569 193.279 1.00 57.19  ? 403 LEU A N   1 
ATOM   1461 C CA  . LEU A 1 403 ? 221.333 182.650 192.371 1.00 39.58  ? 403 LEU A CA  1 
ATOM   1462 C C   . LEU A 1 403 ? 222.419 182.895 191.329 1.00 36.50  ? 403 LEU A C   1 
ATOM   1463 O O   . LEU A 1 403 ? 222.622 184.029 190.893 1.00 43.56  ? 403 LEU A O   1 
ATOM   1464 C CB  . LEU A 1 403 ? 221.043 183.936 193.144 1.00 39.30  ? 403 LEU A CB  1 
ATOM   1465 C CG  . LEU A 1 403 ? 219.759 183.982 193.972 1.00 38.80  ? 403 LEU A CG  1 
ATOM   1466 C CD1 . LEU A 1 403 ? 219.617 185.338 194.638 1.00 35.68  ? 403 LEU A CD1 1 
ATOM   1467 C CD2 . LEU A 1 403 ? 218.549 183.676 193.106 1.00 39.36  ? 403 LEU A CD2 1 
ATOM   1468 N N   . SER A 1 404 ? 223.122 181.835 190.920 1.00 38.31  ? 404 SER A N   1 
ATOM   1469 C CA  . SER A 1 404 ? 224.197 181.988 189.944 1.00 41.61  ? 404 SER A CA  1 
ATOM   1470 C C   . SER A 1 404 ? 223.678 182.505 188.610 1.00 50.94  ? 404 SER A C   1 
ATOM   1471 O O   . SER A 1 404 ? 224.424 183.147 187.858 1.00 53.11  ? 404 SER A O   1 
ATOM   1472 C CB  . SER A 1 404 ? 224.921 180.656 189.750 1.00 48.47  ? 404 SER A CB  1 
ATOM   1473 O OG  . SER A 1 404 ? 224.054 179.686 189.189 1.00 50.50  ? 404 SER A OG  1 
ATOM   1474 N N   . VAL A 1 405 ? 222.406 182.242 188.303 1.00 59.20  ? 405 VAL A N   1 
ATOM   1475 C CA  . VAL A 1 405 ? 221.838 182.684 187.034 1.00 52.12  ? 405 VAL A CA  1 
ATOM   1476 C C   . VAL A 1 405 ? 221.819 184.205 186.960 1.00 45.48  ? 405 VAL A C   1 
ATOM   1477 O O   . VAL A 1 405 ? 221.982 184.789 185.884 1.00 49.42  ? 405 VAL A O   1 
ATOM   1478 C CB  . VAL A 1 405 ? 220.434 182.080 186.840 1.00 45.12  ? 405 VAL A CB  1 
ATOM   1479 C CG1 . VAL A 1 405 ? 219.579 182.967 185.958 1.00 46.36  ? 405 VAL A CG1 1 
ATOM   1480 C CG2 . VAL A 1 405 ? 220.536 180.690 186.249 1.00 52.24  ? 405 VAL A CG2 1 
ATOM   1481 N N   . ILE A 1 406 ? 221.633 184.873 188.101 1.00 42.53  ? 406 ILE A N   1 
ATOM   1482 C CA  . ILE A 1 406 ? 221.579 186.334 188.105 1.00 42.36  ? 406 ILE A CA  1 
ATOM   1483 C C   . ILE A 1 406 ? 222.914 186.922 187.654 1.00 51.88  ? 406 ILE A C   1 
ATOM   1484 O O   . ILE A 1 406 ? 222.965 187.772 186.756 1.00 57.95  ? 406 ILE A O   1 
ATOM   1485 C CB  . ILE A 1 406 ? 221.170 186.851 189.496 1.00 43.51  ? 406 ILE A CB  1 
ATOM   1486 C CG1 . ILE A 1 406 ? 219.651 186.789 189.656 1.00 40.31  ? 406 ILE A CG1 1 
ATOM   1487 C CG2 . ILE A 1 406 ? 221.661 188.274 189.707 1.00 42.24  ? 406 ILE A CG2 1 
ATOM   1488 C CD1 . ILE A 1 406 ? 219.183 186.932 191.085 1.00 45.73  ? 406 ILE A CD1 1 
ATOM   1489 N N   . LEU A 1 407 ? 224.017 186.465 188.256 1.00 59.18  ? 407 LEU A N   1 
ATOM   1490 C CA  . LEU A 1 407 ? 225.329 186.965 187.851 1.00 58.10  ? 407 LEU A CA  1 
ATOM   1491 C C   . LEU A 1 407 ? 225.677 186.517 186.437 1.00 54.56  ? 407 LEU A C   1 
ATOM   1492 O O   . LEU A 1 407 ? 226.323 187.258 185.686 1.00 60.35  ? 407 LEU A O   1 
ATOM   1493 C CB  . LEU A 1 407 ? 226.413 186.517 188.835 1.00 54.15  ? 407 LEU A CB  1 
ATOM   1494 C CG  . LEU A 1 407 ? 226.157 186.536 190.345 1.00 55.64  ? 407 LEU A CG  1 
ATOM   1495 C CD1 . LEU A 1 407 ? 225.526 185.245 190.829 1.00 53.37  ? 407 LEU A CD1 1 
ATOM   1496 C CD2 . LEU A 1 407 ? 227.450 186.813 191.096 1.00 57.62  ? 407 LEU A CD2 1 
ATOM   1497 N N   . MET A 1 408 ? 225.264 185.306 186.061 1.00 58.05  ? 408 MET A N   1 
ATOM   1498 C CA  . MET A 1 408 ? 225.497 184.834 184.700 1.00 65.54  ? 408 MET A CA  1 
ATOM   1499 C C   . MET A 1 408 ? 224.820 185.737 183.676 1.00 73.84  ? 408 MET A C   1 
ATOM   1500 O O   . MET A 1 408 ? 225.429 186.121 182.671 1.00 73.42  ? 408 MET A O   1 
ATOM   1501 C CB  . MET A 1 408 ? 224.987 183.405 184.564 1.00 65.78  ? 408 MET A CB  1 
ATOM   1502 C CG  . MET A 1 408 ? 226.032 182.330 184.741 1.00 64.13  ? 408 MET A CG  1 
ATOM   1503 S SD  . MET A 1 408 ? 225.184 180.749 184.746 1.00 75.03  ? 408 MET A SD  1 
ATOM   1504 C CE  . MET A 1 408 ? 224.156 180.989 183.303 1.00 73.39  ? 408 MET A CE  1 
ATOM   1505 N N   . ASP A 1 409 ? 223.559 186.095 183.923 1.00 67.53  ? 409 ASP A N   1 
ATOM   1506 C CA  . ASP A 1 409 ? 222.833 186.967 183.010 1.00 55.66  ? 409 ASP A CA  1 
ATOM   1507 C C   . ASP A 1 409 ? 223.374 188.387 183.048 1.00 52.87  ? 409 ASP A C   1 
ATOM   1508 O O   . ASP A 1 409 ? 223.334 189.087 182.034 1.00 61.99  ? 409 ASP A O   1 
ATOM   1509 C CB  . ASP A 1 409 ? 221.342 186.950 183.346 1.00 50.75  ? 409 ASP A CB  1 
ATOM   1510 C CG  . ASP A 1 409 ? 220.658 185.673 182.896 1.00 48.53  ? 409 ASP A CG  1 
ATOM   1511 O OD1 . ASP A 1 409 ? 221.351 184.780 182.365 1.00 48.20  ? 409 ASP A OD1 1 
ATOM   1512 O OD2 . ASP A 1 409 ? 219.428 185.559 183.077 1.00 47.46  ? 409 ASP A OD2 1 
ATOM   1513 N N   . LEU A 1 410 ? 223.890 188.828 184.196 1.00 60.83  ? 410 LEU A N   1 
ATOM   1514 C CA  . LEU A 1 410 ? 224.531 190.138 184.253 1.00 62.46  ? 410 LEU A CA  1 
ATOM   1515 C C   . LEU A 1 410 ? 225.786 190.169 183.383 1.00 61.09  ? 410 LEU A C   1 
ATOM   1516 O O   . LEU A 1 410 ? 226.009 191.130 182.633 1.00 61.50  ? 410 LEU A O   1 
ATOM   1517 C CB  . LEU A 1 410 ? 224.838 190.488 185.713 1.00 69.07  ? 410 LEU A CB  1 
ATOM   1518 C CG  . LEU A 1 410 ? 225.270 191.886 186.168 1.00 70.91  ? 410 LEU A CG  1 
ATOM   1519 C CD1 . LEU A 1 410 ? 225.080 192.003 187.670 1.00 68.43  ? 410 LEU A CD1 1 
ATOM   1520 C CD2 . LEU A 1 410 ? 226.713 192.183 185.824 1.00 66.90  ? 410 LEU A CD2 1 
ATOM   1521 N N   . GLU A 1 411 ? 226.608 189.118 183.455 1.00 79.31  ? 411 GLU A N   1 
ATOM   1522 C CA  . GLU A 1 411 ? 227.781 189.031 182.587 1.00 83.18  ? 411 GLU A CA  1 
ATOM   1523 C C   . GLU A 1 411 ? 227.378 188.940 181.120 1.00 86.00  ? 411 GLU A C   1 
ATOM   1524 O O   . GLU A 1 411 ? 228.028 189.535 180.246 1.00 87.96  ? 411 GLU A O   1 
ATOM   1525 C CB  . GLU A 1 411 ? 228.642 187.832 182.982 1.00 82.13  ? 411 GLU A CB  1 
ATOM   1526 C CG  . GLU A 1 411 ? 230.126 188.031 182.727 1.00 84.65  ? 411 GLU A CG  1 
ATOM   1527 C CD  . GLU A 1 411 ? 230.778 188.941 183.750 1.00 84.96  ? 411 GLU A CD  1 
ATOM   1528 O OE1 . GLU A 1 411 ? 230.432 188.841 184.945 1.00 82.17  ? 411 GLU A OE1 1 
ATOM   1529 O OE2 . GLU A 1 411 ? 231.635 189.761 183.357 1.00 83.57  ? 411 GLU A OE2 1 
ATOM   1530 N N   . TYR A 1 412 ? 226.316 188.183 180.830 1.00 86.80  ? 412 TYR A N   1 
ATOM   1531 C CA  . TYR A 1 412 ? 225.779 188.151 179.475 1.00 85.71  ? 412 TYR A CA  1 
ATOM   1532 C C   . TYR A 1 412 ? 225.371 189.544 179.023 1.00 81.14  ? 412 TYR A C   1 
ATOM   1533 O O   . TYR A 1 412 ? 225.591 189.917 177.869 1.00 75.71  ? 412 TYR A O   1 
ATOM   1534 C CB  . TYR A 1 412 ? 224.584 187.201 179.400 1.00 81.67  ? 412 TYR A CB  1 
ATOM   1535 C CG  . TYR A 1 412 ? 223.927 187.154 178.038 1.00 78.96  ? 412 TYR A CG  1 
ATOM   1536 C CD1 . TYR A 1 412 ? 224.687 187.144 176.876 1.00 83.69  ? 412 TYR A CD1 1 
ATOM   1537 C CD2 . TYR A 1 412 ? 222.545 187.141 177.915 1.00 74.32  ? 412 TYR A CD2 1 
ATOM   1538 C CE1 . TYR A 1 412 ? 224.089 187.109 175.631 1.00 84.11  ? 412 TYR A CE1 1 
ATOM   1539 C CE2 . TYR A 1 412 ? 221.940 187.107 176.675 1.00 78.56  ? 412 TYR A CE2 1 
ATOM   1540 C CZ  . TYR A 1 412 ? 222.715 187.090 175.537 1.00 81.25  ? 412 TYR A CZ  1 
ATOM   1541 O OH  . TYR A 1 412 ? 222.114 187.055 174.300 1.00 78.95  ? 412 TYR A OH  1 
ATOM   1542 N N   . MET A 1 413 ? 224.765 190.322 179.919 1.00 85.99  ? 413 MET A N   1 
ATOM   1543 C CA  . MET A 1 413 ? 224.380 191.687 179.585 1.00 86.20  ? 413 MET A CA  1 
ATOM   1544 C C   . MET A 1 413 ? 225.599 192.534 179.251 1.00 91.20  ? 413 MET A C   1 
ATOM   1545 O O   . MET A 1 413 ? 225.585 193.299 178.281 1.00 96.24  ? 413 MET A O   1 
ATOM   1546 C CB  . MET A 1 413 ? 223.592 192.306 180.738 1.00 83.75  ? 413 MET A CB  1 
ATOM   1547 C CG  . MET A 1 413 ? 222.268 192.916 180.322 1.00 80.65  ? 413 MET A CG  1 
ATOM   1548 S SD  . MET A 1 413 ? 221.563 193.949 181.616 1.00 84.07  ? 413 MET A SD  1 
ATOM   1549 C CE  . MET A 1 413 ? 222.540 195.438 181.432 1.00 85.75  ? 413 MET A CE  1 
ATOM   1550 N N   . ILE A 1 414 ? 226.667 192.414 180.045 1.00 91.00  ? 414 ILE A N   1 
ATOM   1551 C CA  . ILE A 1 414 ? 227.872 193.196 179.761 1.00 88.59  ? 414 ILE A CA  1 
ATOM   1552 C C   . ILE A 1 414 ? 228.439 192.832 178.394 1.00 86.97  ? 414 ILE A C   1 
ATOM   1553 O O   . ILE A 1 414 ? 228.739 193.710 177.574 1.00 90.29  ? 414 ILE A O   1 
ATOM   1554 C CB  . ILE A 1 414 ? 228.933 193.022 180.865 1.00 91.18  ? 414 ILE A CB  1 
ATOM   1555 C CG1 . ILE A 1 414 ? 228.311 193.053 182.256 1.00 92.72  ? 414 ILE A CG1 1 
ATOM   1556 C CG2 . ILE A 1 414 ? 230.007 194.093 180.742 1.00 91.16  ? 414 ILE A CG2 1 
ATOM   1557 C CD1 . ILE A 1 414 ? 229.130 192.307 183.281 1.00 89.52  ? 414 ILE A CD1 1 
ATOM   1558 N N   . CYS A 1 415 ? 228.590 191.533 178.122 1.00 96.51  ? 415 CYS A N   1 
ATOM   1559 C CA  . CYS A 1 415 ? 229.186 191.128 176.849 1.00 104.89 ? 415 CYS A CA  1 
ATOM   1560 C C   . CYS A 1 415 ? 228.288 191.500 175.671 1.00 106.44 ? 415 CYS A C   1 
ATOM   1561 O O   . CYS A 1 415 ? 228.773 191.959 174.625 1.00 106.02 ? 415 CYS A O   1 
ATOM   1562 C CB  . CYS A 1 415 ? 229.476 189.628 176.856 1.00 104.09 ? 415 CYS A CB  1 
ATOM   1563 S SG  . CYS A 1 415 ? 228.082 188.592 176.377 1.00 107.33 ? 415 CYS A SG  1 
ATOM   1564 N N   . PHE A 1 416 ? 226.976 191.308 175.826 1.00 101.16 ? 416 PHE A N   1 
ATOM   1565 C CA  . PHE A 1 416 ? 226.023 191.670 174.785 1.00 99.40  ? 416 PHE A CA  1 
ATOM   1566 C C   . PHE A 1 416 ? 226.074 193.161 174.493 1.00 100.89 ? 416 PHE A C   1 
ATOM   1567 O O   . PHE A 1 416 ? 226.151 193.567 173.330 1.00 106.27 ? 416 PHE A O   1 
ATOM   1568 C CB  . PHE A 1 416 ? 224.619 191.242 175.219 1.00 100.55 ? 416 PHE A CB  1 
ATOM   1569 C CG  . PHE A 1 416 ? 223.612 191.210 174.108 1.00 103.21 ? 416 PHE A CG  1 
ATOM   1570 C CD1 . PHE A 1 416 ? 223.584 190.162 173.205 1.00 100.08 ? 416 PHE A CD1 1 
ATOM   1571 C CD2 . PHE A 1 416 ? 222.662 192.209 173.993 1.00 102.60 ? 416 PHE A CD2 1 
ATOM   1572 C CE1 . PHE A 1 416 ? 222.648 190.129 172.189 1.00 100.83 ? 416 PHE A CE1 1 
ATOM   1573 C CE2 . PHE A 1 416 ? 221.724 192.182 172.981 1.00 101.72 ? 416 PHE A CE2 1 
ATOM   1574 C CZ  . PHE A 1 416 ? 221.716 191.140 172.079 1.00 101.95 ? 416 PHE A CZ  1 
ATOM   1575 N N   . TYR A 1 417 ? 226.115 193.972 175.542 1.00 99.76  ? 417 TYR A N   1 
ATOM   1576 C CA  . TYR A 1 417 ? 226.148 195.420 175.360 1.00 100.80 ? 417 TYR A CA  1 
ATOM   1577 C C   . TYR A 1 417 ? 227.479 195.856 174.777 1.00 103.66 ? 417 TYR A C   1 
ATOM   1578 O O   . TYR A 1 417 ? 227.551 196.880 174.105 1.00 106.77 ? 417 TYR A O   1 
ATOM   1579 C CB  . TYR A 1 417 ? 225.811 196.167 176.649 1.00 102.08 ? 417 TYR A CB  1 
ATOM   1580 C CG  . TYR A 1 417 ? 224.321 196.319 176.892 1.00 105.67 ? 417 TYR A CG  1 
ATOM   1581 C CD1 . TYR A 1 417 ? 223.454 195.241 176.751 1.00 103.92 ? 417 TYR A CD1 1 
ATOM   1582 C CD2 . TYR A 1 417 ? 223.780 197.542 177.261 1.00 106.38 ? 417 TYR A CD2 1 
ATOM   1583 C CE1 . TYR A 1 417 ? 222.101 195.373 176.970 1.00 104.03 ? 417 TYR A CE1 1 
ATOM   1584 C CE2 . TYR A 1 417 ? 222.423 197.683 177.481 1.00 104.82 ? 417 TYR A CE2 1 
ATOM   1585 C CZ  . TYR A 1 417 ? 221.593 196.595 177.335 1.00 105.66 ? 417 TYR A CZ  1 
ATOM   1586 O OH  . TYR A 1 417 ? 220.247 196.722 177.556 1.00 107.88 ? 417 TYR A OH  1 
ATOM   1587 N N   . SER A 1 418 ? 228.531 195.081 175.014 1.00 107.69 ? 418 SER A N   1 
ATOM   1588 C CA  . SER A 1 418 ? 229.823 195.390 174.419 1.00 108.98 ? 418 SER A CA  1 
ATOM   1589 C C   . SER A 1 418 ? 229.840 195.084 172.926 1.00 112.38 ? 418 SER A C   1 
ATOM   1590 O O   . SER A 1 418 ? 230.442 195.831 172.145 1.00 113.13 ? 418 SER A O   1 
ATOM   1591 C CB  . SER A 1 418 ? 230.928 194.616 175.137 1.00 108.29 ? 418 SER A CB  1 
ATOM   1592 O OG  . SER A 1 418 ? 231.092 193.324 174.579 1.00 109.49 ? 418 SER A OG  1 
ATOM   1593 N N   . LEU A 1 419 ? 229.193 193.995 172.503 1.00 111.40 ? 419 LEU A N   1 
ATOM   1594 C CA  . LEU A 1 419 ? 229.430 193.555 171.129 1.00 108.63 ? 419 LEU A CA  1 
ATOM   1595 C C   . LEU A 1 419 ? 228.183 193.551 170.238 1.00 108.76 ? 419 LEU A C   1 
ATOM   1596 O O   . LEU A 1 419 ? 228.220 194.101 169.132 1.00 110.81 ? 419 LEU A O   1 
ATOM   1597 C CB  . LEU A 1 419 ? 230.080 192.166 171.149 1.00 107.55 ? 419 LEU A CB  1 
ATOM   1598 C CG  . LEU A 1 419 ? 230.017 191.185 169.971 1.00 110.01 ? 419 LEU A CG  1 
ATOM   1599 C CD1 . LEU A 1 419 ? 230.442 191.823 168.647 1.00 108.12 ? 419 LEU A CD1 1 
ATOM   1600 C CD2 . LEU A 1 419 ? 230.865 189.959 170.267 1.00 110.54 ? 419 LEU A CD2 1 
ATOM   1601 N N   . GLU A 1 420 ? 227.078 192.954 170.691 1.00 108.35 ? 420 GLU A N   1 
ATOM   1602 C CA  . GLU A 1 420 ? 225.976 192.583 169.807 1.00 108.22 ? 420 GLU A CA  1 
ATOM   1603 C C   . GLU A 1 420 ? 224.746 193.485 169.925 1.00 106.38 ? 420 GLU A C   1 
ATOM   1604 O O   . GLU A 1 420 ? 223.620 192.976 169.928 1.00 106.96 ? 420 GLU A O   1 
ATOM   1605 C CB  . GLU A 1 420 ? 225.564 191.131 170.061 1.00 108.68 ? 420 GLU A CB  1 
ATOM   1606 C CG  . GLU A 1 420 ? 226.664 190.115 169.837 1.00 110.32 ? 420 GLU A CG  1 
ATOM   1607 C CD  . GLU A 1 420 ? 226.633 188.999 170.856 1.00 110.09 ? 420 GLU A CD  1 
ATOM   1608 O OE1 . GLU A 1 420 ? 226.291 189.280 172.022 1.00 108.53 ? 420 GLU A OE1 1 
ATOM   1609 O OE2 . GLU A 1 420 ? 226.947 187.845 170.495 1.00 109.76 ? 420 GLU A OE2 1 
ATOM   1610 N N   . LEU A 1 421 ? 224.922 194.805 170.023 1.00 107.47 ? 421 LEU A N   1 
ATOM   1611 C CA  . LEU A 1 421 ? 223.760 195.691 169.948 1.00 111.66 ? 421 LEU A CA  1 
ATOM   1612 C C   . LEU A 1 421 ? 223.520 196.235 168.546 1.00 113.01 ? 421 LEU A C   1 
ATOM   1613 O O   . LEU A 1 421 ? 222.371 196.276 168.091 1.00 111.95 ? 421 LEU A O   1 
ATOM   1614 C CB  . LEU A 1 421 ? 223.883 196.847 170.941 1.00 110.45 ? 421 LEU A CB  1 
ATOM   1615 C CG  . LEU A 1 421 ? 223.316 196.626 172.345 1.00 109.82 ? 421 LEU A CG  1 
ATOM   1616 C CD1 . LEU A 1 421 ? 223.655 195.268 172.878 1.00 109.50 ? 421 LEU A CD1 1 
ATOM   1617 C CD2 . LEU A 1 421 ? 223.813 197.705 173.290 1.00 109.51 ? 421 LEU A CD2 1 
ATOM   1618 N N   . LYS A 1 422 ? 224.577 196.665 167.854 1.00 116.00 ? 422 LYS A N   1 
ATOM   1619 C CA  . LYS A 1 422 ? 224.450 197.437 166.617 1.00 115.25 ? 422 LYS A CA  1 
ATOM   1620 C C   . LYS A 1 422 ? 223.638 198.710 166.881 1.00 116.50 ? 422 LYS A C   1 
ATOM   1621 O O   . LYS A 1 422 ? 222.523 198.897 166.388 1.00 118.23 ? 422 LYS A O   1 
ATOM   1622 C CB  . LYS A 1 422 ? 223.824 196.598 165.495 1.00 115.25 ? 422 LYS A CB  1 
ATOM   1623 C CG  . LYS A 1 422 ? 224.798 195.694 164.759 1.00 114.77 ? 422 LYS A CG  1 
ATOM   1624 C CD  . LYS A 1 422 ? 224.060 194.768 163.804 1.00 116.25 ? 422 LYS A CD  1 
ATOM   1625 C CE  . LYS A 1 422 ? 225.022 193.899 163.011 1.00 115.71 ? 422 LYS A CE  1 
ATOM   1626 N NZ  . LYS A 1 422 ? 225.041 192.496 163.510 1.00 113.86 ? 422 LYS A NZ  1 
ATOM   1627 N N   . TRP A 1 423 ? 224.244 199.577 167.699 1.00 119.54 ? 423 TRP A N   1 
ATOM   1628 C CA  . TRP A 1 423 ? 223.621 200.780 168.248 1.00 121.42 ? 423 TRP A CA  1 
ATOM   1629 C C   . TRP A 1 423 ? 222.808 201.576 167.234 1.00 122.76 ? 423 TRP A C   1 
ATOM   1630 O O   . TRP A 1 423 ? 221.833 202.240 167.601 1.00 122.13 ? 423 TRP A O   1 
ATOM   1631 C CB  . TRP A 1 423 ? 224.694 201.691 168.852 1.00 122.59 ? 423 TRP A CB  1 
ATOM   1632 C CG  . TRP A 1 423 ? 225.636 201.000 169.789 1.00 123.47 ? 423 TRP A CG  1 
ATOM   1633 C CD1 . TRP A 1 423 ? 226.792 200.354 169.461 1.00 123.17 ? 423 TRP A CD1 1 
ATOM   1634 C CD2 . TRP A 1 423 ? 225.524 200.922 171.216 1.00 122.32 ? 423 TRP A CD2 1 
ATOM   1635 N NE1 . TRP A 1 423 ? 227.396 199.859 170.592 1.00 123.18 ? 423 TRP A NE1 1 
ATOM   1636 C CE2 . TRP A 1 423 ? 226.638 200.197 171.683 1.00 122.46 ? 423 TRP A CE2 1 
ATOM   1637 C CE3 . TRP A 1 423 ? 224.586 201.387 172.142 1.00 119.79 ? 423 TRP A CE3 1 
ATOM   1638 C CZ2 . TRP A 1 423 ? 226.839 199.927 173.035 1.00 120.82 ? 423 TRP A CZ2 1 
ATOM   1639 C CZ3 . TRP A 1 423 ? 224.787 201.118 173.484 1.00 118.76 ? 423 TRP A CZ3 1 
ATOM   1640 C CH2 . TRP A 1 423 ? 225.905 200.396 173.917 1.00 118.19 ? 423 TRP A CH2 1 
ATOM   1641 N N   . ASP A 1 424 ? 223.203 201.527 165.960 1.00 130.25 ? 424 ASP A N   1 
ATOM   1642 C CA  . ASP A 1 424 ? 222.477 202.266 164.933 1.00 130.71 ? 424 ASP A CA  1 
ATOM   1643 C C   . ASP A 1 424 ? 221.048 201.757 164.789 1.00 130.05 ? 424 ASP A C   1 
ATOM   1644 O O   . ASP A 1 424 ? 220.116 202.546 164.593 1.00 129.06 ? 424 ASP A O   1 
ATOM   1645 C CB  . ASP A 1 424 ? 223.220 202.174 163.601 1.00 132.52 ? 424 ASP A CB  1 
ATOM   1646 C CG  . ASP A 1 424 ? 224.671 202.602 163.714 1.00 132.26 ? 424 ASP A CG  1 
ATOM   1647 O OD1 . ASP A 1 424 ? 225.093 202.988 164.824 1.00 129.99 ? 424 ASP A OD1 1 
ATOM   1648 O OD2 . ASP A 1 424 ? 225.388 202.552 162.693 1.00 131.72 ? 424 ASP A OD2 1 
ATOM   1649 N N   . GLU A 1 425 ? 220.856 200.443 164.880 1.00 128.01 ? 425 GLU A N   1 
ATOM   1650 C CA  . GLU A 1 425 ? 219.527 199.863 164.748 1.00 127.05 ? 425 GLU A CA  1 
ATOM   1651 C C   . GLU A 1 425 ? 218.630 200.294 165.903 1.00 125.05 ? 425 GLU A C   1 
ATOM   1652 O O   . GLU A 1 425 ? 219.037 200.277 167.068 1.00 124.25 ? 425 GLU A O   1 
ATOM   1653 C CB  . GLU A 1 425 ? 219.624 198.339 164.690 1.00 127.88 ? 425 GLU A CB  1 
ATOM   1654 C CG  . GLU A 1 425 ? 218.288 197.619 164.671 1.00 127.75 ? 425 GLU A CG  1 
ATOM   1655 C CD  . GLU A 1 425 ? 218.434 196.125 164.876 1.00 129.05 ? 425 GLU A CD  1 
ATOM   1656 O OE1 . GLU A 1 425 ? 219.582 195.650 165.002 1.00 128.78 ? 425 GLU A OE1 1 
ATOM   1657 O OE2 . GLU A 1 425 ? 217.401 195.424 164.911 1.00 128.59 ? 425 GLU A OE2 1 
ATOM   1658 N N   . SER A 1 426 ? 217.398 200.688 165.569 1.00 122.07 ? 426 SER A N   1 
ATOM   1659 C CA  . SER A 1 426 ? 216.455 201.132 166.592 1.00 124.56 ? 426 SER A CA  1 
ATOM   1660 C C   . SER A 1 426 ? 216.045 199.986 167.509 1.00 123.43 ? 426 SER A C   1 
ATOM   1661 O O   . SER A 1 426 ? 215.903 200.174 168.723 1.00 122.18 ? 426 SER A O   1 
ATOM   1662 C CB  . SER A 1 426 ? 215.225 201.756 165.934 1.00 125.56 ? 426 SER A CB  1 
ATOM   1663 O OG  . SER A 1 426 ? 214.443 200.773 165.278 1.00 126.77 ? 426 SER A OG  1 
ATOM   1664 N N   . LYS A 1 427 ? 215.847 198.796 166.948 1.00 117.23 ? 427 LYS A N   1 
ATOM   1665 C CA  . LYS A 1 427 ? 215.456 197.608 167.704 1.00 117.94 ? 427 LYS A CA  1 
ATOM   1666 C C   . LYS A 1 427 ? 216.632 196.661 167.908 1.00 121.04 ? 427 LYS A C   1 
ATOM   1667 O O   . LYS A 1 427 ? 216.481 195.438 167.823 1.00 121.41 ? 427 LYS A O   1 
ATOM   1668 C CB  . LYS A 1 427 ? 214.304 196.893 167.006 1.00 116.04 ? 427 LYS A CB  1 
ATOM   1669 C CG  . LYS A 1 427 ? 213.098 197.766 166.708 1.00 118.21 ? 427 LYS A CG  1 
ATOM   1670 C CD  . LYS A 1 427 ? 212.631 198.509 167.945 1.00 118.00 ? 427 LYS A CD  1 
ATOM   1671 C CE  . LYS A 1 427 ? 211.870 197.578 168.877 1.00 118.34 ? 427 LYS A CE  1 
ATOM   1672 N NZ  . LYS A 1 427 ? 210.569 197.148 168.294 1.00 116.85 ? 427 LYS A NZ  1 
ATOM   1673 N N   . GLY A 1 428 ? 217.820 197.211 168.171 1.00 121.37 ? 428 GLY A N   1 
ATOM   1674 C CA  . GLY A 1 428 ? 219.019 196.402 168.318 1.00 117.65 ? 428 GLY A CA  1 
ATOM   1675 C C   . GLY A 1 428 ? 218.950 195.378 169.431 1.00 116.59 ? 428 GLY A C   1 
ATOM   1676 O O   . GLY A 1 428 ? 219.669 194.374 169.382 1.00 117.12 ? 428 GLY A O   1 
ATOM   1677 N N   . LEU A 1 429 ? 218.106 195.607 170.440 1.00 102.84 ? 429 LEU A N   1 
ATOM   1678 C CA  . LEU A 1 429 ? 217.939 194.627 171.506 1.00 103.75 ? 429 LEU A CA  1 
ATOM   1679 C C   . LEU A 1 429 ? 217.329 193.326 171.000 1.00 104.65 ? 429 LEU A C   1 
ATOM   1680 O O   . LEU A 1 429 ? 217.535 192.277 171.620 1.00 106.14 ? 429 LEU A O   1 
ATOM   1681 C CB  . LEU A 1 429 ? 217.077 195.213 172.626 1.00 104.05 ? 429 LEU A CB  1 
ATOM   1682 C CG  . LEU A 1 429 ? 217.060 194.469 173.962 1.00 101.22 ? 429 LEU A CG  1 
ATOM   1683 C CD1 . LEU A 1 429 ? 218.354 194.705 174.722 1.00 103.33 ? 429 LEU A CD1 1 
ATOM   1684 C CD2 . LEU A 1 429 ? 215.866 194.900 174.795 1.00 96.71  ? 429 LEU A CD2 1 
ATOM   1685 N N   . LEU A 1 430 ? 216.594 193.370 169.888 1.00 108.20 ? 430 LEU A N   1 
ATOM   1686 C CA  . LEU A 1 430 ? 215.970 192.192 169.285 1.00 108.61 ? 430 LEU A CA  1 
ATOM   1687 C C   . LEU A 1 430 ? 216.517 192.034 167.872 1.00 110.91 ? 430 LEU A C   1 
ATOM   1688 O O   . LEU A 1 430 ? 215.987 192.632 166.923 1.00 112.49 ? 430 LEU A O   1 
ATOM   1689 C CB  . LEU A 1 430 ? 214.448 192.323 169.274 1.00 106.43 ? 430 LEU A CB  1 
ATOM   1690 C CG  . LEU A 1 430 ? 213.729 192.213 170.620 1.00 107.59 ? 430 LEU A CG  1 
ATOM   1691 C CD1 . LEU A 1 430 ? 212.227 192.098 170.417 1.00 108.01 ? 430 LEU A CD1 1 
ATOM   1692 C CD2 . LEU A 1 430 ? 214.256 191.034 171.423 1.00 106.08 ? 430 LEU A CD2 1 
ATOM   1693 N N   . PRO A 1 431 ? 217.580 191.253 167.686 1.00 110.81 ? 431 PRO A N   1 
ATOM   1694 C CA  . PRO A 1 431 ? 218.153 191.096 166.342 1.00 111.37 ? 431 PRO A CA  1 
ATOM   1695 C C   . PRO A 1 431 ? 217.182 190.412 165.390 1.00 111.40 ? 431 PRO A C   1 
ATOM   1696 O O   . PRO A 1 431 ? 216.379 189.566 165.790 1.00 113.46 ? 431 PRO A O   1 
ATOM   1697 C CB  . PRO A 1 431 ? 219.403 190.242 166.585 1.00 111.63 ? 431 PRO A CB  1 
ATOM   1698 C CG  . PRO A 1 431 ? 219.147 189.549 167.881 1.00 107.41 ? 431 PRO A CG  1 
ATOM   1699 C CD  . PRO A 1 431 ? 218.333 190.499 168.702 1.00 106.38 ? 431 PRO A CD  1 
ATOM   1700 N N   . ASN A 1 432 ? 217.269 190.786 164.114 1.00 118.48 ? 432 ASN A N   1 
ATOM   1701 C CA  . ASN A 1 432 ? 216.402 190.258 163.068 1.00 121.54 ? 432 ASN A CA  1 
ATOM   1702 C C   . ASN A 1 432 ? 216.961 189.010 162.399 1.00 124.38 ? 432 ASN A C   1 
ATOM   1703 O O   . ASN A 1 432 ? 216.359 188.516 161.440 1.00 126.45 ? 432 ASN A O   1 
ATOM   1704 C CB  . ASN A 1 432 ? 216.142 191.333 162.008 1.00 122.65 ? 432 ASN A CB  1 
ATOM   1705 C CG  . ASN A 1 432 ? 214.730 191.280 161.458 1.00 122.17 ? 432 ASN A CG  1 
ATOM   1706 O OD1 . ASN A 1 432 ? 213.894 190.515 161.936 1.00 122.05 ? 432 ASN A OD1 1 
ATOM   1707 N ND2 . ASN A 1 432 ? 214.458 192.098 160.448 1.00 122.30 ? 432 ASN A ND2 1 
ATOM   1708 N N   . ASN A 1 433 ? 218.097 188.495 162.873 1.00 122.77 ? 433 ASN A N   1 
ATOM   1709 C CA  . ASN A 1 433 ? 218.681 187.308 162.258 1.00 123.25 ? 433 ASN A CA  1 
ATOM   1710 C C   . ASN A 1 433 ? 217.761 186.101 162.396 1.00 122.22 ? 433 ASN A C   1 
ATOM   1711 O O   . ASN A 1 433 ? 217.639 185.296 161.465 1.00 121.86 ? 433 ASN A O   1 
ATOM   1712 C CB  . ASN A 1 433 ? 220.047 187.013 162.879 1.00 123.26 ? 433 ASN A CB  1 
ATOM   1713 C CG  . ASN A 1 433 ? 220.964 188.221 162.876 1.00 123.74 ? 433 ASN A CG  1 
ATOM   1714 O OD1 . ASN A 1 433 ? 220.613 189.280 162.356 1.00 124.10 ? 433 ASN A OD1 1 
ATOM   1715 N ND2 . ASN A 1 433 ? 222.147 188.067 163.459 1.00 120.74 ? 433 ASN A ND2 1 
ATOM   1716 N N   . SER A 1 434 ? 217.125 185.948 163.559 1.00 123.10 ? 434 SER A N   1 
ATOM   1717 C CA  . SER A 1 434 ? 216.257 184.833 163.932 1.00 124.91 ? 434 SER A CA  1 
ATOM   1718 C C   . SER A 1 434 ? 217.025 183.527 164.075 1.00 127.55 ? 434 SER A C   1 
ATOM   1719 O O   . SER A 1 434 ? 216.431 182.511 164.458 1.00 127.88 ? 434 SER A O   1 
ATOM   1720 C CB  . SER A 1 434 ? 215.094 184.628 162.949 1.00 124.24 ? 434 SER A CB  1 
ATOM   1721 O OG  . SER A 1 434 ? 214.167 183.680 163.446 1.00 123.49 ? 434 SER A OG  1 
ATOM   1722 N N   . GLU A 1 435 ? 218.323 183.516 163.783 1.00 137.05 ? 435 GLU A N   1 
ATOM   1723 C CA  . GLU A 1 435 ? 219.194 182.370 164.006 1.00 135.51 ? 435 GLU A CA  1 
ATOM   1724 C C   . GLU A 1 435 ? 220.345 182.836 164.883 1.00 135.08 ? 435 GLU A C   1 
ATOM   1725 O O   . GLU A 1 435 ? 221.109 183.723 164.488 1.00 136.34 ? 435 GLU A O   1 
ATOM   1726 C CB  . GLU A 1 435 ? 219.709 181.799 162.684 1.00 134.75 ? 435 GLU A CB  1 
ATOM   1727 C CG  . GLU A 1 435 ? 218.611 181.411 161.706 1.00 134.94 ? 435 GLU A CG  1 
ATOM   1728 C CD  . GLU A 1 435 ? 219.155 180.802 160.430 1.00 136.08 ? 435 GLU A CD  1 
ATOM   1729 O OE1 . GLU A 1 435 ? 220.389 180.645 160.324 1.00 136.38 ? 435 GLU A OE1 1 
ATOM   1730 O OE2 . GLU A 1 435 ? 218.348 180.479 159.532 1.00 136.98 ? 435 GLU A OE2 1 
ATOM   1731 N N   . GLU A 1 436 ? 220.467 182.244 166.066 1.00 118.68 ? 436 GLU A N   1 
ATOM   1732 C CA  . GLU A 1 436 ? 221.388 182.721 167.090 1.00 119.31 ? 436 GLU A CA  1 
ATOM   1733 C C   . GLU A 1 436 ? 222.743 182.050 166.905 1.00 120.87 ? 436 GLU A C   1 
ATOM   1734 O O   . GLU A 1 436 ? 222.887 180.846 167.137 1.00 120.73 ? 436 GLU A O   1 
ATOM   1735 C CB  . GLU A 1 436 ? 220.821 182.455 168.482 1.00 120.39 ? 436 GLU A CB  1 
ATOM   1736 C CG  . GLU A 1 436 ? 219.530 183.199 168.759 1.00 120.96 ? 436 GLU A CG  1 
ATOM   1737 C CD  . GLU A 1 436 ? 218.578 182.409 169.628 1.00 121.99 ? 436 GLU A CD  1 
ATOM   1738 O OE1 . GLU A 1 436 ? 219.051 181.635 170.486 1.00 121.42 ? 436 GLU A OE1 1 
ATOM   1739 O OE2 . GLU A 1 436 ? 217.352 182.557 169.444 1.00 118.96 ? 436 GLU A OE2 1 
ATOM   1740 N N   . SER A 1 437 ? 223.735 182.839 166.485 1.00 127.17 ? 437 SER A N   1 
ATOM   1741 C CA  . SER A 1 437 ? 225.108 182.371 166.345 1.00 126.84 ? 437 SER A CA  1 
ATOM   1742 C C   . SER A 1 437 ? 226.091 183.411 166.868 1.00 126.49 ? 437 SER A C   1 
ATOM   1743 O O   . SER A 1 437 ? 227.245 183.458 166.427 1.00 126.14 ? 437 SER A O   1 
ATOM   1744 C CB  . SER A 1 437 ? 225.429 182.029 164.889 1.00 124.57 ? 437 SER A CB  1 
ATOM   1745 O OG  . SER A 1 437 ? 225.357 183.181 164.067 1.00 125.27 ? 437 SER A OG  1 
ATOM   1746 N N   . GLY A 1 438 ? 225.650 184.249 167.803 1.00 122.59 ? 438 GLY A N   1 
ATOM   1747 C CA  . GLY A 1 438 ? 226.502 185.301 168.313 1.00 122.86 ? 438 GLY A CA  1 
ATOM   1748 C C   . GLY A 1 438 ? 227.617 184.774 169.195 1.00 123.90 ? 438 GLY A C   1 
ATOM   1749 O O   . GLY A 1 438 ? 227.589 183.647 169.691 1.00 122.73 ? 438 GLY A O   1 
ATOM   1750 N N   . ILE A 1 439 ? 228.627 185.625 169.386 1.00 123.87 ? 439 ILE A N   1 
ATOM   1751 C CA  . ILE A 1 439 ? 229.771 185.253 170.211 1.00 125.12 ? 439 ILE A CA  1 
ATOM   1752 C C   . ILE A 1 439 ? 229.350 185.074 171.665 1.00 123.88 ? 439 ILE A C   1 
ATOM   1753 O O   . ILE A 1 439 ? 229.884 184.218 172.378 1.00 124.35 ? 439 ILE A O   1 
ATOM   1754 C CB  . ILE A 1 439 ? 230.893 186.298 170.067 1.00 124.17 ? 439 ILE A CB  1 
ATOM   1755 C CG1 . ILE A 1 439 ? 231.220 186.527 168.590 1.00 121.66 ? 439 ILE A CG1 1 
ATOM   1756 C CG2 . ILE A 1 439 ? 232.138 185.859 170.822 1.00 125.11 ? 439 ILE A CG2 1 
ATOM   1757 C CD1 . ILE A 1 439 ? 231.659 185.276 167.860 1.00 123.14 ? 439 ILE A CD1 1 
ATOM   1758 N N   . CYS A 1 440 ? 228.396 185.882 172.132 1.00 117.72 ? 440 CYS A N   1 
ATOM   1759 C CA  . CYS A 1 440 ? 227.953 185.766 173.517 1.00 117.61 ? 440 CYS A CA  1 
ATOM   1760 C C   . CYS A 1 440 ? 227.073 184.541 173.724 1.00 118.18 ? 440 CYS A C   1 
ATOM   1761 O O   . CYS A 1 440 ? 227.109 183.922 174.794 1.00 115.03 ? 440 CYS A O   1 
ATOM   1762 C CB  . CYS A 1 440 ? 227.212 187.030 173.943 1.00 119.55 ? 440 CYS A CB  1 
ATOM   1763 S SG  . CYS A 1 440 ? 228.291 188.406 174.367 1.00 124.49 ? 440 CYS A SG  1 
ATOM   1764 N N   . HIS A 1 441 ? 226.264 184.181 172.722 1.00 120.83 ? 441 HIS A N   1 
ATOM   1765 C CA  . HIS A 1 441 ? 225.397 183.016 172.867 1.00 119.69 ? 441 HIS A CA  1 
ATOM   1766 C C   . HIS A 1 441 ? 226.214 181.747 173.063 1.00 121.34 ? 441 HIS A C   1 
ATOM   1767 O O   . HIS A 1 441 ? 225.892 180.917 173.921 1.00 121.32 ? 441 HIS A O   1 
ATOM   1768 C CB  . HIS A 1 441 ? 224.480 182.879 171.654 1.00 119.38 ? 441 HIS A CB  1 
ATOM   1769 C CG  . HIS A 1 441 ? 223.421 181.833 171.819 1.00 120.21 ? 441 HIS A CG  1 
ATOM   1770 N ND1 . HIS A 1 441 ? 222.776 181.250 170.750 1.00 121.60 ? 441 HIS A ND1 1 
ATOM   1771 C CD2 . HIS A 1 441 ? 222.894 181.267 172.930 1.00 119.31 ? 441 HIS A CD2 1 
ATOM   1772 C CE1 . HIS A 1 441 ? 221.898 180.370 171.195 1.00 119.45 ? 441 HIS A CE1 1 
ATOM   1773 N NE2 . HIS A 1 441 ? 221.950 180.360 172.515 1.00 119.09 ? 441 HIS A NE2 1 
ATOM   1774 N N   . LYS A 1 442 ? 227.270 181.573 172.274 1.00 123.75 ? 442 LYS A N   1 
ATOM   1775 C CA  . LYS A 1 442 ? 228.229 180.516 172.548 1.00 123.17 ? 442 LYS A CA  1 
ATOM   1776 C C   . LYS A 1 442 ? 229.090 180.902 173.745 1.00 123.49 ? 442 LYS A C   1 
ATOM   1777 O O   . LYS A 1 442 ? 229.337 182.081 174.009 1.00 124.98 ? 442 LYS A O   1 
ATOM   1778 C CB  . LYS A 1 442 ? 229.101 180.246 171.320 1.00 120.53 ? 442 LYS A CB  1 
ATOM   1779 C CG  . LYS A 1 442 ? 230.071 181.363 170.977 1.00 120.80 ? 442 LYS A CG  1 
ATOM   1780 C CD  . LYS A 1 442 ? 230.664 181.176 169.590 1.00 120.68 ? 442 LYS A CD  1 
ATOM   1781 C CE  . LYS A 1 442 ? 229.592 181.266 168.515 1.00 121.07 ? 442 LYS A CE  1 
ATOM   1782 N NZ  . LYS A 1 442 ? 230.174 181.240 167.145 1.00 120.18 ? 442 LYS A NZ  1 
ATOM   1783 N N   . TYR A 1 443 ? 229.534 179.895 174.488 1.00 121.66 ? 443 TYR A N   1 
ATOM   1784 C CA  . TYR A 1 443 ? 230.303 180.106 175.707 1.00 121.05 ? 443 TYR A CA  1 
ATOM   1785 C C   . TYR A 1 443 ? 231.671 179.443 175.611 1.00 121.28 ? 443 TYR A C   1 
ATOM   1786 O O   . TYR A 1 443 ? 232.181 178.875 176.579 1.00 119.07 ? 443 TYR A O   1 
ATOM   1787 C CB  . TYR A 1 443 ? 229.530 179.605 176.924 1.00 120.51 ? 443 TYR A CB  1 
ATOM   1788 C CG  . TYR A 1 443 ? 228.083 180.048 176.936 1.00 120.30 ? 443 TYR A CG  1 
ATOM   1789 C CD1 . TYR A 1 443 ? 227.750 181.395 176.894 1.00 121.13 ? 443 TYR A CD1 1 
ATOM   1790 C CD2 . TYR A 1 443 ? 227.052 179.121 176.984 1.00 120.16 ? 443 TYR A CD2 1 
ATOM   1791 C CE1 . TYR A 1 443 ? 226.429 181.806 176.905 1.00 120.92 ? 443 TYR A CE1 1 
ATOM   1792 C CE2 . TYR A 1 443 ? 225.728 179.522 176.993 1.00 121.80 ? 443 TYR A CE2 1 
ATOM   1793 C CZ  . TYR A 1 443 ? 225.423 180.865 176.954 1.00 122.35 ? 443 TYR A CZ  1 
ATOM   1794 O OH  . TYR A 1 443 ? 224.108 181.270 176.963 1.00 121.94 ? 443 TYR A OH  1 
ATOM   1795 N N   . THR A 1 444 ? 232.281 179.513 174.425 1.00 132.32 ? 444 THR A N   1 
ATOM   1796 C CA  . THR A 1 444 ? 233.615 178.959 174.231 1.00 134.65 ? 444 THR A CA  1 
ATOM   1797 C C   . THR A 1 444 ? 234.691 179.790 174.918 1.00 133.70 ? 444 THR A C   1 
ATOM   1798 O O   . THR A 1 444 ? 235.781 179.272 175.186 1.00 132.22 ? 444 THR A O   1 
ATOM   1799 C CB  . THR A 1 444 ? 233.920 178.843 172.735 1.00 134.54 ? 444 THR A CB  1 
ATOM   1800 O OG1 . THR A 1 444 ? 232.738 178.428 172.038 1.00 133.82 ? 444 THR A OG1 1 
ATOM   1801 C CG2 . THR A 1 444 ? 235.022 177.822 172.487 1.00 131.69 ? 444 THR A CG2 1 
ATOM   1802 N N   . TYR A 1 445 ? 234.411 181.063 175.211 1.00 123.15 ? 445 TYR A N   1 
ATOM   1803 C CA  . TYR A 1 445 ? 235.404 181.910 175.864 1.00 121.28 ? 445 TYR A CA  1 
ATOM   1804 C C   . TYR A 1 445 ? 235.749 181.389 177.254 1.00 122.45 ? 445 TYR A C   1 
ATOM   1805 O O   . TYR A 1 445 ? 236.920 181.391 177.653 1.00 124.83 ? 445 TYR A O   1 
ATOM   1806 C CB  . TYR A 1 445 ? 234.898 183.351 175.940 1.00 120.47 ? 445 TYR A CB  1 
ATOM   1807 C CG  . TYR A 1 445 ? 235.970 184.390 175.698 1.00 123.42 ? 445 TYR A CG  1 
ATOM   1808 C CD1 . TYR A 1 445 ? 236.807 184.308 174.593 1.00 123.49 ? 445 TYR A CD1 1 
ATOM   1809 C CD2 . TYR A 1 445 ? 236.143 185.454 176.574 1.00 122.64 ? 445 TYR A CD2 1 
ATOM   1810 C CE1 . TYR A 1 445 ? 237.788 185.255 174.368 1.00 124.43 ? 445 TYR A CE1 1 
ATOM   1811 C CE2 . TYR A 1 445 ? 237.122 186.406 176.357 1.00 122.24 ? 445 TYR A CE2 1 
ATOM   1812 C CZ  . TYR A 1 445 ? 237.941 186.302 175.253 1.00 123.80 ? 445 TYR A CZ  1 
ATOM   1813 O OH  . TYR A 1 445 ? 238.916 187.248 175.032 1.00 122.88 ? 445 TYR A OH  1 
ATOM   1814 N N   . GLY A 1 446 ? 234.746 180.938 178.005 1.00 107.16 ? 446 GLY A N   1 
ATOM   1815 C CA  . GLY A 1 446 ? 234.956 180.376 179.321 1.00 106.27 ? 446 GLY A CA  1 
ATOM   1816 C C   . GLY A 1 446 ? 234.638 181.301 180.476 1.00 105.59 ? 446 GLY A C   1 
ATOM   1817 O O   . GLY A 1 446 ? 234.648 180.847 181.627 1.00 102.02 ? 446 GLY A O   1 
ATOM   1818 N N   . VAL A 1 447 ? 234.363 182.581 180.211 1.00 95.80  ? 447 VAL A N   1 
ATOM   1819 C CA  . VAL A 1 447 ? 234.028 183.501 181.295 1.00 89.04  ? 447 VAL A CA  1 
ATOM   1820 C C   . VAL A 1 447 ? 232.712 183.104 181.954 1.00 90.10  ? 447 VAL A C   1 
ATOM   1821 O O   . VAL A 1 447 ? 232.493 183.385 183.142 1.00 93.38  ? 447 VAL A O   1 
ATOM   1822 C CB  . VAL A 1 447 ? 234.001 184.952 180.777 1.00 89.72  ? 447 VAL A CB  1 
ATOM   1823 C CG1 . VAL A 1 447 ? 232.688 185.257 180.067 1.00 90.67  ? 447 VAL A CG1 1 
ATOM   1824 C CG2 . VAL A 1 447 ? 234.236 185.928 181.920 1.00 92.41  ? 447 VAL A CG2 1 
ATOM   1825 N N   . ARG A 1 448 ? 231.819 182.443 181.210 1.00 86.69  ? 448 ARG A N   1 
ATOM   1826 C CA  . ARG A 1 448 ? 230.576 181.966 181.803 1.00 86.49  ? 448 ARG A CA  1 
ATOM   1827 C C   . ARG A 1 448 ? 230.851 180.932 182.885 1.00 89.96  ? 448 ARG A C   1 
ATOM   1828 O O   . ARG A 1 448 ? 230.179 180.911 183.922 1.00 91.77  ? 448 ARG A O   1 
ATOM   1829 C CB  . ARG A 1 448 ? 229.657 181.387 180.729 1.00 85.31  ? 448 ARG A CB  1 
ATOM   1830 C CG  . ARG A 1 448 ? 228.292 180.982 181.259 1.00 85.97  ? 448 ARG A CG  1 
ATOM   1831 C CD  . ARG A 1 448 ? 227.190 181.438 180.326 1.00 88.92  ? 448 ARG A CD  1 
ATOM   1832 N NE  . ARG A 1 448 ? 227.447 182.778 179.813 1.00 92.00  ? 448 ARG A NE  1 
ATOM   1833 C CZ  . ARG A 1 448 ? 226.680 183.834 180.048 1.00 86.62  ? 448 ARG A CZ  1 
ATOM   1834 N NH1 . ARG A 1 448 ? 225.584 183.743 180.783 1.00 83.92  ? 448 ARG A NH1 1 
ATOM   1835 N NH2 . ARG A 1 448 ? 227.022 185.010 179.532 1.00 82.69  ? 448 ARG A NH2 1 
ATOM   1836 N N   . ALA A 1 449 ? 231.846 180.072 182.666 1.00 80.22  ? 449 ALA A N   1 
ATOM   1837 C CA  . ALA A 1 449 ? 232.212 179.106 183.694 1.00 75.90  ? 449 ALA A CA  1 
ATOM   1838 C C   . ALA A 1 449 ? 232.660 179.807 184.971 1.00 77.37  ? 449 ALA A C   1 
ATOM   1839 O O   . ALA A 1 449 ? 232.235 179.435 186.070 1.00 78.72  ? 449 ALA A O   1 
ATOM   1840 C CB  . ALA A 1 449 ? 233.308 178.179 183.173 1.00 76.86  ? 449 ALA A CB  1 
ATOM   1841 N N   . ILE A 1 450 ? 233.496 180.839 184.845 1.00 87.04  ? 450 ILE A N   1 
ATOM   1842 C CA  . ILE A 1 450 ? 233.992 181.543 186.026 1.00 91.14  ? 450 ILE A CA  1 
ATOM   1843 C C   . ILE A 1 450 ? 232.857 182.260 186.749 1.00 90.07  ? 450 ILE A C   1 
ATOM   1844 O O   . ILE A 1 450 ? 232.779 182.239 187.986 1.00 91.00  ? 450 ILE A O   1 
ATOM   1845 C CB  . ILE A 1 450 ? 235.120 182.513 185.634 1.00 90.16  ? 450 ILE A CB  1 
ATOM   1846 C CG1 . ILE A 1 450 ? 235.938 181.939 184.477 1.00 89.56  ? 450 ILE A CG1 1 
ATOM   1847 C CG2 . ILE A 1 450 ? 236.015 182.798 186.830 1.00 90.22  ? 450 ILE A CG2 1 
ATOM   1848 C CD1 . ILE A 1 450 ? 236.775 182.967 183.752 1.00 91.82  ? 450 ILE A CD1 1 
ATOM   1849 N N   . VAL A 1 451 ? 231.971 182.925 186.000 1.00 74.38  ? 451 VAL A N   1 
ATOM   1850 C CA  . VAL A 1 451 ? 230.849 183.605 186.639 1.00 71.10  ? 451 VAL A CA  1 
ATOM   1851 C C   . VAL A 1 451 ? 229.800 182.629 187.144 1.00 73.97  ? 451 VAL A C   1 
ATOM   1852 O O   . VAL A 1 451 ? 228.874 183.038 187.852 1.00 87.90  ? 451 VAL A O   1 
ATOM   1853 C CB  . VAL A 1 451 ? 230.191 184.634 185.698 1.00 80.09  ? 451 VAL A CB  1 
ATOM   1854 C CG1 . VAL A 1 451 ? 231.208 185.678 185.262 1.00 81.60  ? 451 VAL A CG1 1 
ATOM   1855 C CG2 . VAL A 1 451 ? 229.544 183.954 184.513 1.00 79.41  ? 451 VAL A CG2 1 
ATOM   1856 N N   . GLN A 1 452 ? 229.906 181.352 186.775 1.00 64.57  ? 452 GLN A N   1 
ATOM   1857 C CA  . GLN A 1 452 ? 229.102 180.328 187.429 1.00 68.79  ? 452 GLN A CA  1 
ATOM   1858 C C   . GLN A 1 452 ? 229.762 179.825 188.709 1.00 71.01  ? 452 GLN A C   1 
ATOM   1859 O O   . GLN A 1 452 ? 229.063 179.514 189.680 1.00 70.42  ? 452 GLN A O   1 
ATOM   1860 C CB  . GLN A 1 452 ? 228.851 179.166 186.467 1.00 72.00  ? 452 GLN A CB  1 
ATOM   1861 C CG  . GLN A 1 452 ? 227.516 178.467 186.665 1.00 69.46  ? 452 GLN A CG  1 
ATOM   1862 C CD  . GLN A 1 452 ? 227.519 177.527 187.853 1.00 74.34  ? 452 GLN A CD  1 
ATOM   1863 O OE1 . GLN A 1 452 ? 226.635 177.585 188.707 1.00 75.15  ? 452 GLN A OE1 1 
ATOM   1864 N NE2 . GLN A 1 452 ? 228.516 176.653 187.913 1.00 76.45  ? 452 GLN A NE2 1 
ATOM   1865 N N   . CYS A 1 453 ? 231.096 179.735 188.730 1.00 68.20  ? 453 CYS A N   1 
ATOM   1866 C CA  . CYS A 1 453 ? 231.796 179.289 189.933 1.00 62.71  ? 453 CYS A CA  1 
ATOM   1867 C C   . CYS A 1 453 ? 231.848 180.339 191.034 1.00 68.87  ? 453 CYS A C   1 
ATOM   1868 O O   . CYS A 1 453 ? 231.980 179.964 192.204 1.00 68.52  ? 453 CYS A O   1 
ATOM   1869 C CB  . CYS A 1 453 ? 233.239 178.865 189.638 1.00 63.45  ? 453 CYS A CB  1 
ATOM   1870 S SG  . CYS A 1 453 ? 233.555 177.932 188.142 1.00 84.71  ? 453 CYS A SG  1 
ATOM   1871 N N   . ILE A 1 454 ? 231.768 181.625 190.697 1.00 70.55  ? 454 ILE A N   1 
ATOM   1872 C CA  . ILE A 1 454 ? 232.061 182.685 191.668 1.00 67.49  ? 454 ILE A CA  1 
ATOM   1873 C C   . ILE A 1 454 ? 231.259 182.538 192.966 1.00 67.22  ? 454 ILE A C   1 
ATOM   1874 O O   . ILE A 1 454 ? 231.855 182.694 194.041 1.00 72.57  ? 454 ILE A O   1 
ATOM   1875 C CB  . ILE A 1 454 ? 231.888 184.086 191.040 1.00 66.93  ? 454 ILE A CB  1 
ATOM   1876 C CG1 . ILE A 1 454 ? 231.840 185.196 192.100 1.00 64.71  ? 454 ILE A CG1 1 
ATOM   1877 C CG2 . ILE A 1 454 ? 230.697 184.168 190.115 1.00 68.83  ? 454 ILE A CG2 1 
ATOM   1878 C CD1 . ILE A 1 454 ? 233.097 185.316 192.943 1.00 66.36  ? 454 ILE A CD1 1 
ATOM   1879 N N   . PRO A 1 455 ? 229.953 182.223 192.969 1.00 59.79  ? 455 PRO A N   1 
ATOM   1880 C CA  . PRO A 1 455 ? 229.296 182.050 194.278 1.00 56.76  ? 455 PRO A CA  1 
ATOM   1881 C C   . PRO A 1 455 ? 229.789 180.823 195.024 1.00 63.66  ? 455 PRO A C   1 
ATOM   1882 O O   . PRO A 1 455 ? 230.027 180.886 196.239 1.00 60.57  ? 455 PRO A O   1 
ATOM   1883 C CB  . PRO A 1 455 ? 227.811 181.945 193.915 1.00 49.60  ? 455 PRO A CB  1 
ATOM   1884 C CG  . PRO A 1 455 ? 227.811 181.365 192.568 1.00 52.27  ? 455 PRO A CG  1 
ATOM   1885 C CD  . PRO A 1 455 ? 229.005 181.943 191.871 1.00 56.28  ? 455 PRO A CD  1 
ATOM   1886 N N   . ALA A 1 456 ? 229.955 179.700 194.321 1.00 66.40  ? 456 ALA A N   1 
ATOM   1887 C CA  . ALA A 1 456 ? 230.570 178.530 194.933 1.00 60.33  ? 456 ALA A CA  1 
ATOM   1888 C C   . ALA A 1 456 ? 232.010 178.810 195.336 1.00 57.25  ? 456 ALA A C   1 
ATOM   1889 O O   . ALA A 1 456 ? 232.490 178.261 196.331 1.00 64.27  ? 456 ALA A O   1 
ATOM   1890 C CB  . ALA A 1 456 ? 230.508 177.345 193.974 1.00 58.87  ? 456 ALA A CB  1 
ATOM   1891 N N   . TRP A 1 457 ? 232.708 179.657 194.578 1.00 57.48  ? 457 TRP A N   1 
ATOM   1892 C CA  . TRP A 1 457 ? 234.057 180.069 194.953 1.00 61.42  ? 457 TRP A CA  1 
ATOM   1893 C C   . TRP A 1 457 ? 234.052 180.798 196.291 1.00 67.00  ? 457 TRP A C   1 
ATOM   1894 O O   . TRP A 1 457 ? 234.873 180.509 197.175 1.00 78.73  ? 457 TRP A O   1 
ATOM   1895 C CB  . TRP A 1 457 ? 234.631 180.943 193.838 1.00 67.69  ? 457 TRP A CB  1 
ATOM   1896 C CG  . TRP A 1 457 ? 236.022 181.447 194.032 1.00 70.81  ? 457 TRP A CG  1 
ATOM   1897 C CD1 . TRP A 1 457 ? 237.180 180.775 193.773 1.00 69.89  ? 457 TRP A CD1 1 
ATOM   1898 C CD2 . TRP A 1 457 ? 236.406 182.757 194.466 1.00 70.86  ? 457 TRP A CD2 1 
ATOM   1899 N NE1 . TRP A 1 457 ? 238.262 181.576 194.045 1.00 67.83  ? 457 TRP A NE1 1 
ATOM   1900 C CE2 . TRP A 1 457 ? 237.814 182.800 194.465 1.00 70.86  ? 457 TRP A CE2 1 
ATOM   1901 C CE3 . TRP A 1 457 ? 235.697 183.893 194.864 1.00 71.06  ? 457 TRP A CE3 1 
ATOM   1902 C CZ2 . TRP A 1 457 ? 238.526 183.932 194.857 1.00 71.11  ? 457 TRP A CZ2 1 
ATOM   1903 C CZ3 . TRP A 1 457 ? 236.405 185.017 195.247 1.00 71.83  ? 457 TRP A CZ3 1 
ATOM   1904 C CH2 . TRP A 1 457 ? 237.805 185.028 195.242 1.00 71.89  ? 457 TRP A CH2 1 
ATOM   1905 N N   . LEU A 1 458 ? 233.111 181.729 196.465 1.00 60.10  ? 458 LEU A N   1 
ATOM   1906 C CA  . LEU A 1 458 ? 232.992 182.448 197.727 1.00 56.58  ? 458 LEU A CA  1 
ATOM   1907 C C   . LEU A 1 458 ? 232.642 181.502 198.867 1.00 58.89  ? 458 LEU A C   1 
ATOM   1908 O O   . LEU A 1 458 ? 233.201 181.608 199.963 1.00 65.25  ? 458 LEU A O   1 
ATOM   1909 C CB  . LEU A 1 458 ? 231.946 183.556 197.606 1.00 58.88  ? 458 LEU A CB  1 
ATOM   1910 C CG  . LEU A 1 458 ? 232.201 184.611 196.529 1.00 64.89  ? 458 LEU A CG  1 
ATOM   1911 C CD1 . LEU A 1 458 ? 230.893 185.220 196.050 1.00 61.91  ? 458 LEU A CD1 1 
ATOM   1912 C CD2 . LEU A 1 458 ? 233.146 185.682 197.042 1.00 68.27  ? 458 LEU A CD2 1 
ATOM   1913 N N   . ARG A 1 459 ? 231.717 180.568 198.629 1.00 54.65  ? 459 ARG A N   1 
ATOM   1914 C CA  . ARG A 1 459 ? 231.345 179.627 199.684 1.00 57.87  ? 459 ARG A CA  1 
ATOM   1915 C C   . ARG A 1 459 ? 232.518 178.731 200.068 1.00 60.56  ? 459 ARG A C   1 
ATOM   1916 O O   . ARG A 1 459 ? 232.751 178.476 201.256 1.00 64.79  ? 459 ARG A O   1 
ATOM   1917 C CB  . ARG A 1 459 ? 230.150 178.780 199.249 1.00 57.10  ? 459 ARG A CB  1 
ATOM   1918 C CG  . ARG A 1 459 ? 228.820 179.281 199.781 1.00 55.04  ? 459 ARG A CG  1 
ATOM   1919 C CD  . ARG A 1 459 ? 228.896 179.586 201.269 1.00 42.03  ? 459 ARG A CD  1 
ATOM   1920 N NE  . ARG A 1 459 ? 229.262 178.436 202.083 1.00 36.10  ? 459 ARG A NE  1 
ATOM   1921 C CZ  . ARG A 1 459 ? 229.556 178.502 203.374 1.00 47.22  ? 459 ARG A CZ  1 
ATOM   1922 N NH1 . ARG A 1 459 ? 229.596 179.659 204.014 1.00 55.31  ? 459 ARG A NH1 1 
ATOM   1923 N NH2 . ARG A 1 459 ? 229.818 177.382 204.039 1.00 55.14  ? 459 ARG A NH2 1 
ATOM   1924 N N   . PHE A 1 460 ? 233.267 178.248 199.076 1.00 56.27  ? 460 PHE A N   1 
ATOM   1925 C CA  . PHE A 1 460 ? 234.410 177.381 199.333 1.00 54.96  ? 460 PHE A CA  1 
ATOM   1926 C C   . PHE A 1 460 ? 235.478 178.105 200.143 1.00 56.60  ? 460 PHE A C   1 
ATOM   1927 O O   . PHE A 1 460 ? 235.997 177.567 201.130 1.00 64.28  ? 460 PHE A O   1 
ATOM   1928 C CB  . PHE A 1 460 ? 234.968 176.882 197.998 1.00 59.37  ? 460 PHE A CB  1 
ATOM   1929 C CG  . PHE A 1 460 ? 236.264 176.135 198.108 1.00 63.52  ? 460 PHE A CG  1 
ATOM   1930 C CD1 . PHE A 1 460 ? 236.305 174.857 198.639 1.00 66.76  ? 460 PHE A CD1 1 
ATOM   1931 C CD2 . PHE A 1 460 ? 237.441 176.703 197.650 1.00 64.01  ? 460 PHE A CD2 1 
ATOM   1932 C CE1 . PHE A 1 460 ? 237.499 174.168 198.726 1.00 65.02  ? 460 PHE A CE1 1 
ATOM   1933 C CE2 . PHE A 1 460 ? 238.636 176.019 197.734 1.00 65.54  ? 460 PHE A CE2 1 
ATOM   1934 C CZ  . PHE A 1 460 ? 238.665 174.750 198.273 1.00 65.21  ? 460 PHE A CZ  1 
ATOM   1935 N N   . ILE A 1 461 ? 235.810 179.338 199.752 1.00 57.46  ? 461 ILE A N   1 
ATOM   1936 C CA  . ILE A 1 461 ? 236.813 180.083 200.504 1.00 61.21  ? 461 ILE A CA  1 
ATOM   1937 C C   . ILE A 1 461 ? 236.312 180.490 201.887 1.00 63.87  ? 461 ILE A C   1 
ATOM   1938 O O   . ILE A 1 461 ? 237.095 180.487 202.845 1.00 65.22  ? 461 ILE A O   1 
ATOM   1939 C CB  . ILE A 1 461 ? 237.304 181.284 199.677 1.00 63.75  ? 461 ILE A CB  1 
ATOM   1940 C CG1 . ILE A 1 461 ? 238.334 180.797 198.660 1.00 62.88  ? 461 ILE A CG1 1 
ATOM   1941 C CG2 . ILE A 1 461 ? 237.901 182.359 200.562 1.00 66.88  ? 461 ILE A CG2 1 
ATOM   1942 C CD1 . ILE A 1 461 ? 238.419 181.632 197.440 1.00 64.61  ? 461 ILE A CD1 1 
ATOM   1943 N N   . GLN A 1 462 ? 235.026 180.819 202.033 1.00 64.51  ? 462 GLN A N   1 
ATOM   1944 C CA  . GLN A 1 462 ? 234.481 181.075 203.361 1.00 65.19  ? 462 GLN A CA  1 
ATOM   1945 C C   . GLN A 1 462 ? 234.580 179.850 204.256 1.00 68.60  ? 462 GLN A C   1 
ATOM   1946 O O   . GLN A 1 462 ? 234.920 179.977 205.437 1.00 72.59  ? 462 GLN A O   1 
ATOM   1947 C CB  . GLN A 1 462 ? 233.020 181.519 203.263 1.00 61.39  ? 462 GLN A CB  1 
ATOM   1948 C CG  . GLN A 1 462 ? 232.828 183.001 203.013 1.00 64.05  ? 462 GLN A CG  1 
ATOM   1949 C CD  . GLN A 1 462 ? 231.385 183.361 202.727 1.00 67.76  ? 462 GLN A CD  1 
ATOM   1950 O OE1 . GLN A 1 462 ? 231.070 183.931 201.683 1.00 73.87  ? 462 GLN A OE1 1 
ATOM   1951 N NE2 . GLN A 1 462 ? 230.498 183.028 203.657 1.00 69.08  ? 462 GLN A NE2 1 
ATOM   1952 N N   . CYS A 1 463 ? 234.290 178.666 203.717 1.00 62.72  ? 463 CYS A N   1 
ATOM   1953 C CA  . CYS A 1 463 ? 234.404 177.448 204.510 1.00 61.90  ? 463 CYS A CA  1 
ATOM   1954 C C   . CYS A 1 463 ? 235.854 177.160 204.883 1.00 65.90  ? 463 CYS A C   1 
ATOM   1955 O O   . CYS A 1 463 ? 236.134 176.716 206.002 1.00 66.97  ? 463 CYS A O   1 
ATOM   1956 C CB  . CYS A 1 463 ? 233.792 176.275 203.752 1.00 55.39  ? 463 CYS A CB  1 
ATOM   1957 S SG  . CYS A 1 463 ? 232.070 176.002 204.186 1.00 67.42  ? 463 CYS A SG  1 
ATOM   1958 N N   . LEU A 1 464 ? 236.789 177.398 203.959 1.00 72.34  ? 464 LEU A N   1 
ATOM   1959 C CA  . LEU A 1 464 ? 238.201 177.229 204.294 1.00 69.74  ? 464 LEU A CA  1 
ATOM   1960 C C   . LEU A 1 464 ? 238.629 178.195 205.393 1.00 69.50  ? 464 LEU A C   1 
ATOM   1961 O O   . LEU A 1 464 ? 239.373 177.817 206.307 1.00 72.40  ? 464 LEU A O   1 
ATOM   1962 C CB  . LEU A 1 464 ? 239.073 177.419 203.053 1.00 69.17  ? 464 LEU A CB  1 
ATOM   1963 C CG  . LEU A 1 464 ? 238.925 176.413 201.912 1.00 65.73  ? 464 LEU A CG  1 
ATOM   1964 C CD1 . LEU A 1 464 ? 240.109 176.522 200.966 1.00 69.38  ? 464 LEU A CD1 1 
ATOM   1965 C CD2 . LEU A 1 464 ? 238.790 174.998 202.447 1.00 65.46  ? 464 LEU A CD2 1 
ATOM   1966 N N   . ARG A 1 465 ? 238.175 179.448 205.318 1.00 79.62  ? 465 ARG A N   1 
ATOM   1967 C CA  . ARG A 1 465 ? 238.497 180.419 206.358 1.00 82.42  ? 465 ARG A CA  1 
ATOM   1968 C C   . ARG A 1 465 ? 237.894 180.013 207.697 1.00 83.24  ? 465 ARG A C   1 
ATOM   1969 O O   . ARG A 1 465 ? 238.534 180.161 208.745 1.00 84.77  ? 465 ARG A O   1 
ATOM   1970 C CB  . ARG A 1 465 ? 238.010 181.807 205.942 1.00 85.45  ? 465 ARG A CB  1 
ATOM   1971 C CG  . ARG A 1 465 ? 238.068 182.852 207.044 1.00 85.71  ? 465 ARG A CG  1 
ATOM   1972 C CD  . ARG A 1 465 ? 239.483 183.024 207.576 1.00 87.65  ? 465 ARG A CD  1 
ATOM   1973 N NE  . ARG A 1 465 ? 239.508 183.730 208.852 1.00 85.12  ? 465 ARG A NE  1 
ATOM   1974 C CZ  . ARG A 1 465 ? 239.275 185.027 208.999 1.00 85.61  ? 465 ARG A CZ  1 
ATOM   1975 N NH1 . ARG A 1 465 ? 239.017 185.806 207.962 1.00 87.22  ? 465 ARG A NH1 1 
ATOM   1976 N NH2 . ARG A 1 465 ? 239.306 185.557 210.218 1.00 82.90  ? 465 ARG A NH2 1 
ATOM   1977 N N   . ARG A 1 466 ? 236.665 179.498 207.684 1.00 80.76  ? 466 ARG A N   1 
ATOM   1978 C CA  . ARG A 1 466 ? 236.046 179.031 208.918 1.00 79.38  ? 466 ARG A CA  1 
ATOM   1979 C C   . ARG A 1 466 ? 236.793 177.841 209.505 1.00 78.45  ? 466 ARG A C   1 
ATOM   1980 O O   . ARG A 1 466 ? 236.944 177.754 210.729 1.00 78.80  ? 466 ARG A O   1 
ATOM   1981 C CB  . ARG A 1 466 ? 234.580 178.672 208.673 1.00 76.94  ? 466 ARG A CB  1 
ATOM   1982 C CG  . ARG A 1 466 ? 233.660 179.109 209.797 1.00 76.73  ? 466 ARG A CG  1 
ATOM   1983 C CD  . ARG A 1 466 ? 232.273 178.502 209.670 1.00 76.86  ? 466 ARG A CD  1 
ATOM   1984 N NE  . ARG A 1 466 ? 231.390 178.937 210.747 1.00 75.48  ? 466 ARG A NE  1 
ATOM   1985 C CZ  . ARG A 1 466 ? 231.543 178.624 212.027 1.00 76.44  ? 466 ARG A CZ  1 
ATOM   1986 N NH1 . ARG A 1 466 ? 232.519 177.830 212.436 1.00 78.17  ? 466 ARG A NH1 1 
ATOM   1987 N NH2 . ARG A 1 466 ? 230.689 179.114 212.921 1.00 76.56  ? 466 ARG A NH2 1 
ATOM   1988 N N   . TYR A 1 467 ? 237.262 176.922 208.657 1.00 79.76  ? 467 TYR A N   1 
ATOM   1989 C CA  . TYR A 1 467 ? 238.113 175.834 209.127 1.00 81.65  ? 467 TYR A CA  1 
ATOM   1990 C C   . TYR A 1 467 ? 239.403 176.351 209.743 1.00 81.43  ? 467 TYR A C   1 
ATOM   1991 O O   . TYR A 1 467 ? 239.816 175.868 210.802 1.00 80.45  ? 467 TYR A O   1 
ATOM   1992 C CB  . TYR A 1 467 ? 238.450 174.879 207.983 1.00 79.79  ? 467 TYR A CB  1 
ATOM   1993 C CG  . TYR A 1 467 ? 239.567 173.915 208.316 1.00 80.87  ? 467 TYR A CG  1 
ATOM   1994 C CD1 . TYR A 1 467 ? 239.461 173.046 209.395 1.00 82.41  ? 467 TYR A CD1 1 
ATOM   1995 C CD2 . TYR A 1 467 ? 240.729 173.878 207.558 1.00 81.85  ? 467 TYR A CD2 1 
ATOM   1996 C CE1 . TYR A 1 467 ? 240.479 172.165 209.706 1.00 82.46  ? 467 TYR A CE1 1 
ATOM   1997 C CE2 . TYR A 1 467 ? 241.753 173.000 207.861 1.00 84.47  ? 467 TYR A CE2 1 
ATOM   1998 C CZ  . TYR A 1 467 ? 241.622 172.146 208.936 1.00 85.59  ? 467 TYR A CZ  1 
ATOM   1999 O OH  . TYR A 1 467 ? 242.638 171.270 209.242 1.00 85.90  ? 467 TYR A OH  1 
ATOM   2000 N N   . ARG A 1 468 ? 240.049 177.322 209.096 1.00 81.97  ? 468 ARG A N   1 
ATOM   2001 C CA  . ARG A 1 468 ? 241.256 177.912 209.663 1.00 81.82  ? 468 ARG A CA  1 
ATOM   2002 C C   . ARG A 1 468 ? 240.976 178.549 211.017 1.00 82.01  ? 468 ARG A C   1 
ATOM   2003 O O   . ARG A 1 468 ? 241.800 178.448 211.934 1.00 84.27  ? 468 ARG A O   1 
ATOM   2004 C CB  . ARG A 1 468 ? 241.836 178.940 208.691 1.00 81.04  ? 468 ARG A CB  1 
ATOM   2005 C CG  . ARG A 1 468 ? 242.792 179.939 209.317 1.00 79.95  ? 468 ARG A CG  1 
ATOM   2006 C CD  . ARG A 1 468 ? 242.742 181.271 208.588 1.00 82.66  ? 468 ARG A CD  1 
ATOM   2007 N NE  . ARG A 1 468 ? 242.909 181.111 207.148 1.00 82.59  ? 468 ARG A NE  1 
ATOM   2008 C CZ  . ARG A 1 468 ? 242.889 182.109 206.275 1.00 80.69  ? 468 ARG A CZ  1 
ATOM   2009 N NH1 . ARG A 1 468 ? 242.719 183.363 206.663 1.00 81.85  ? 468 ARG A NH1 1 
ATOM   2010 N NH2 . ARG A 1 468 ? 243.044 181.843 204.982 1.00 78.09  ? 468 ARG A NH2 1 
ATOM   2011 N N   . ASP A 1 469 ? 239.821 179.198 211.162 1.00 90.08  ? 469 ASP A N   1 
ATOM   2012 C CA  . ASP A 1 469 ? 239.443 179.792 212.440 1.00 93.20  ? 469 ASP A CA  1 
ATOM   2013 C C   . ASP A 1 469 ? 239.203 178.730 213.509 1.00 93.54  ? 469 ASP A C   1 
ATOM   2014 O O   . ASP A 1 469 ? 239.605 178.903 214.665 1.00 93.68  ? 469 ASP A O   1 
ATOM   2015 C CB  . ASP A 1 469 ? 238.199 180.665 212.265 1.00 92.94  ? 469 ASP A CB  1 
ATOM   2016 C CG  . ASP A 1 469 ? 238.459 181.888 211.408 1.00 94.00  ? 469 ASP A CG  1 
ATOM   2017 O OD1 . ASP A 1 469 ? 239.629 182.117 211.036 1.00 94.16  ? 469 ASP A OD1 1 
ATOM   2018 O OD2 . ASP A 1 469 ? 237.494 182.620 211.105 1.00 91.21  ? 469 ASP A OD2 1 
ATOM   2019 N N   . THR A 1 470 ? 238.548 177.624 213.146 1.00 91.54  ? 470 THR A N   1 
ATOM   2020 C CA  . THR A 1 470 ? 238.138 176.631 214.133 1.00 91.31  ? 470 THR A CA  1 
ATOM   2021 C C   . THR A 1 470 ? 239.038 175.403 214.192 1.00 87.92  ? 470 THR A C   1 
ATOM   2022 O O   . THR A 1 470 ? 239.011 174.692 215.203 1.00 86.98  ? 470 THR A O   1 
ATOM   2023 C CB  . THR A 1 470 ? 236.695 176.176 213.867 1.00 91.61  ? 470 THR A CB  1 
ATOM   2024 O OG1 . THR A 1 470 ? 236.184 175.505 215.026 1.00 94.27  ? 470 THR A OG1 1 
ATOM   2025 C CG2 . THR A 1 470 ? 236.638 175.229 212.680 1.00 88.81  ? 470 THR A CG2 1 
ATOM   2026 N N   . LYS A 1 471 ? 239.828 175.138 213.148 1.00 90.17  ? 471 LYS A N   1 
ATOM   2027 C CA  . LYS A 1 471 ? 240.722 173.977 213.100 1.00 91.69  ? 471 LYS A CA  1 
ATOM   2028 C C   . LYS A 1 471 ? 239.958 172.675 213.345 1.00 93.79  ? 471 LYS A C   1 
ATOM   2029 O O   . LYS A 1 471 ? 240.413 171.785 214.067 1.00 97.73  ? 471 LYS A O   1 
ATOM   2030 C CB  . LYS A 1 471 ? 241.877 174.132 214.093 1.00 92.44  ? 471 LYS A CB  1 
ATOM   2031 C CG  . LYS A 1 471 ? 242.784 175.320 213.812 1.00 92.58  ? 471 LYS A CG  1 
ATOM   2032 C CD  . LYS A 1 471 ? 243.756 175.022 212.683 1.00 93.28  ? 471 LYS A CD  1 
ATOM   2033 C CE  . LYS A 1 471 ? 245.064 175.775 212.870 1.00 94.03  ? 471 LYS A CE  1 
ATOM   2034 N NZ  . LYS A 1 471 ? 244.838 177.195 213.257 1.00 92.26  ? 471 LYS A NZ  1 
ATOM   2035 N N   . ARG A 1 472 ? 238.779 172.567 212.734 1.00 86.77  ? 472 ARG A N   1 
ATOM   2036 C CA  . ARG A 1 472 ? 237.927 171.391 212.869 1.00 86.61  ? 472 ARG A CA  1 
ATOM   2037 C C   . ARG A 1 472 ? 237.547 170.898 211.481 1.00 85.61  ? 472 ARG A C   1 
ATOM   2038 O O   . ARG A 1 472 ? 237.000 171.661 210.678 1.00 85.59  ? 472 ARG A O   1 
ATOM   2039 C CB  . ARG A 1 472 ? 236.678 171.708 213.695 1.00 82.19  ? 472 ARG A CB  1 
ATOM   2040 C CG  . ARG A 1 472 ? 235.575 170.678 213.567 1.00 85.01  ? 472 ARG A CG  1 
ATOM   2041 C CD  . ARG A 1 472 ? 234.459 170.930 214.569 1.00 83.50  ? 472 ARG A CD  1 
ATOM   2042 N NE  . ARG A 1 472 ? 233.520 169.815 214.625 1.00 84.43  ? 472 ARG A NE  1 
ATOM   2043 C CZ  . ARG A 1 472 ? 232.354 169.847 215.254 1.00 83.97  ? 472 ARG A CZ  1 
ATOM   2044 N NH1 . ARG A 1 472 ? 231.943 170.930 215.894 1.00 82.37  ? 472 ARG A NH1 1 
ATOM   2045 N NH2 . ARG A 1 472 ? 231.579 168.766 215.241 1.00 82.57  ? 472 ARG A NH2 1 
ATOM   2046 N N   . ALA A 1 473 ? 237.833 169.624 211.203 1.00 82.49  ? 473 ALA A N   1 
ATOM   2047 C CA  . ALA A 1 473 ? 237.608 169.089 209.863 1.00 77.85  ? 473 ALA A CA  1 
ATOM   2048 C C   . ALA A 1 473 ? 236.128 168.850 209.590 1.00 80.80  ? 473 ALA A C   1 
ATOM   2049 O O   . ALA A 1 473 ? 235.643 169.121 208.486 1.00 84.01  ? 473 ALA A O   1 
ATOM   2050 C CB  . ALA A 1 473 ? 238.403 167.798 209.676 1.00 80.95  ? 473 ALA A CB  1 
ATOM   2051 N N   . PHE A 1 474 ? 235.394 168.346 210.578 1.00 85.68  ? 474 PHE A N   1 
ATOM   2052 C CA  . PHE A 1 474 ? 233.984 168.031 210.395 1.00 85.79  ? 474 PHE A CA  1 
ATOM   2053 C C   . PHE A 1 474 ? 233.151 169.242 210.791 1.00 87.71  ? 474 PHE A C   1 
ATOM   2054 O O   . PHE A 1 474 ? 233.132 169.602 211.974 1.00 89.10  ? 474 PHE A O   1 
ATOM   2055 C CB  . PHE A 1 474 ? 233.599 166.825 211.241 1.00 86.34  ? 474 PHE A CB  1 
ATOM   2056 C CG  . PHE A 1 474 ? 232.492 165.987 210.656 1.00 89.86  ? 474 PHE A CG  1 
ATOM   2057 C CD1 . PHE A 1 474 ? 231.487 166.557 209.896 1.00 88.34  ? 474 PHE A CD1 1 
ATOM   2058 C CD2 . PHE A 1 474 ? 232.465 164.617 210.868 1.00 90.40  ? 474 PHE A CD2 1 
ATOM   2059 C CE1 . PHE A 1 474 ? 230.475 165.783 209.362 1.00 90.52  ? 474 PHE A CE1 1 
ATOM   2060 C CE2 . PHE A 1 474 ? 231.457 163.837 210.336 1.00 89.99  ? 474 PHE A CE2 1 
ATOM   2061 C CZ  . PHE A 1 474 ? 230.460 164.421 209.582 1.00 93.76  ? 474 PHE A CZ  1 
ATOM   2062 N N   . PRO A 1 475 ? 232.428 169.880 209.861 1.00 73.64  ? 475 PRO A N   1 
ATOM   2063 C CA  . PRO A 1 475 ? 232.236 169.540 208.452 1.00 75.03  ? 475 PRO A CA  1 
ATOM   2064 C C   . PRO A 1 475 ? 232.932 170.491 207.490 1.00 76.15  ? 475 PRO A C   1 
ATOM   2065 O O   . PRO A 1 475 ? 232.584 170.532 206.312 1.00 76.83  ? 475 PRO A O   1 
ATOM   2066 C CB  . PRO A 1 475 ? 230.724 169.668 208.312 1.00 75.39  ? 475 PRO A CB  1 
ATOM   2067 C CG  . PRO A 1 475 ? 230.436 170.916 209.145 1.00 71.53  ? 475 PRO A CG  1 
ATOM   2068 C CD  . PRO A 1 475 ? 231.470 170.924 210.265 1.00 68.25  ? 475 PRO A CD  1 
ATOM   2069 N N   . HIS A 1 476 ? 233.905 171.272 207.963 1.00 72.37  ? 476 HIS A N   1 
ATOM   2070 C CA  . HIS A 1 476 ? 234.434 172.373 207.164 1.00 72.67  ? 476 HIS A CA  1 
ATOM   2071 C C   . HIS A 1 476 ? 235.108 171.880 205.888 1.00 73.50  ? 476 HIS A C   1 
ATOM   2072 O O   . HIS A 1 476 ? 234.892 172.436 204.807 1.00 75.24  ? 476 HIS A O   1 
ATOM   2073 C CB  . HIS A 1 476 ? 235.395 173.208 208.007 1.00 69.87  ? 476 HIS A CB  1 
ATOM   2074 C CG  . HIS A 1 476 ? 234.733 173.917 209.147 1.00 64.96  ? 476 HIS A CG  1 
ATOM   2075 N ND1 . HIS A 1 476 ? 234.771 175.287 209.295 1.00 69.45  ? 476 HIS A ND1 1 
ATOM   2076 C CD2 . HIS A 1 476 ? 234.010 173.447 210.191 1.00 65.46  ? 476 HIS A CD2 1 
ATOM   2077 C CE1 . HIS A 1 476 ? 234.104 175.629 210.382 1.00 73.03  ? 476 HIS A CE1 1 
ATOM   2078 N NE2 . HIS A 1 476 ? 233.632 174.531 210.945 1.00 72.15  ? 476 HIS A NE2 1 
ATOM   2079 N N   . LEU A 1 477 ? 235.918 170.826 205.987 1.00 69.61  ? 477 LEU A N   1 
ATOM   2080 C CA  . LEU A 1 477 ? 236.503 170.256 204.778 1.00 68.41  ? 477 LEU A CA  1 
ATOM   2081 C C   . LEU A 1 477 ? 235.463 169.489 203.969 1.00 68.67  ? 477 LEU A C   1 
ATOM   2082 O O   . LEU A 1 477 ? 235.527 169.461 202.735 1.00 73.00  ? 477 LEU A O   1 
ATOM   2083 C CB  . LEU A 1 477 ? 237.697 169.367 205.128 1.00 77.82  ? 477 LEU A CB  1 
ATOM   2084 C CG  . LEU A 1 477 ? 239.000 170.102 205.458 1.00 80.27  ? 477 LEU A CG  1 
ATOM   2085 C CD1 . LEU A 1 477 ? 239.218 171.260 204.495 1.00 73.65  ? 477 LEU A CD1 1 
ATOM   2086 C CD2 . LEU A 1 477 ? 239.027 170.597 206.892 1.00 75.17  ? 477 LEU A CD2 1 
ATOM   2087 N N   . VAL A 1 478 ? 234.491 168.870 204.644 1.00 66.70  ? 478 VAL A N   1 
ATOM   2088 C CA  . VAL A 1 478 ? 233.381 168.241 203.933 1.00 71.73  ? 478 VAL A CA  1 
ATOM   2089 C C   . VAL A 1 478 ? 232.583 169.290 203.169 1.00 76.67  ? 478 VAL A C   1 
ATOM   2090 O O   . VAL A 1 478 ? 232.181 169.077 202.016 1.00 72.41  ? 478 VAL A O   1 
ATOM   2091 C CB  . VAL A 1 478 ? 232.491 167.460 204.918 1.00 68.10  ? 478 VAL A CB  1 
ATOM   2092 C CG1 . VAL A 1 478 ? 231.618 166.456 204.181 1.00 63.11  ? 478 VAL A CG1 1 
ATOM   2093 C CG2 . VAL A 1 478 ? 233.332 166.778 205.970 1.00 65.95  ? 478 VAL A CG2 1 
ATOM   2094 N N   . ASN A 1 479 ? 232.333 170.438 203.806 1.00 75.41  ? 479 ASN A N   1 
ATOM   2095 C CA  . ASN A 1 479 ? 231.658 171.537 203.124 1.00 68.19  ? 479 ASN A CA  1 
ATOM   2096 C C   . ASN A 1 479 ? 232.501 172.070 201.973 1.00 71.81  ? 479 ASN A C   1 
ATOM   2097 O O   . ASN A 1 479 ? 231.968 172.463 200.928 1.00 76.69  ? 479 ASN A O   1 
ATOM   2098 C CB  . ASN A 1 479 ? 231.349 172.655 204.115 1.00 60.19  ? 479 ASN A CB  1 
ATOM   2099 C CG  . ASN A 1 479 ? 230.031 173.344 203.819 1.00 66.12  ? 479 ASN A CG  1 
ATOM   2100 O OD1 . ASN A 1 479 ? 229.293 172.927 202.932 1.00 69.00  ? 479 ASN A OD1 1 
ATOM   2101 N ND2 . ASN A 1 479 ? 229.745 174.422 204.538 1.00 69.63  ? 479 ASN A ND2 1 
ATOM   2102 N N   . ALA A 1 480 ? 233.822 172.114 202.161 1.00 65.43  ? 480 ALA A N   1 
ATOM   2103 C CA  . ALA A 1 480 ? 234.713 172.532 201.087 1.00 62.47  ? 480 ALA A CA  1 
ATOM   2104 C C   . ALA A 1 480 ? 234.599 171.595 199.896 1.00 54.92  ? 480 ALA A C   1 
ATOM   2105 O O   . ALA A 1 480 ? 234.584 172.039 198.745 1.00 50.46  ? 480 ALA A O   1 
ATOM   2106 C CB  . ALA A 1 480 ? 236.157 172.583 201.590 1.00 63.32  ? 480 ALA A CB  1 
ATOM   2107 N N   . GLY A 1 481 ? 234.524 170.292 200.158 1.00 58.63  ? 481 GLY A N   1 
ATOM   2108 C CA  . GLY A 1 481 ? 234.325 169.340 199.078 1.00 60.57  ? 481 GLY A CA  1 
ATOM   2109 C C   . GLY A 1 481 ? 232.985 169.517 198.390 1.00 62.64  ? 481 GLY A C   1 
ATOM   2110 O O   . GLY A 1 481 ? 232.892 169.438 197.160 1.00 69.55  ? 481 GLY A O   1 
ATOM   2111 N N   . LYS A 1 482 ? 231.927 169.751 199.172 1.00 62.40  ? 482 LYS A N   1 
ATOM   2112 C CA  . LYS A 1 482 ? 230.605 169.952 198.585 1.00 67.77  ? 482 LYS A CA  1 
ATOM   2113 C C   . LYS A 1 482 ? 230.557 171.198 197.708 1.00 66.05  ? 482 LYS A C   1 
ATOM   2114 O O   . LYS A 1 482 ? 229.916 171.184 196.652 1.00 61.19  ? 482 LYS A O   1 
ATOM   2115 C CB  . LYS A 1 482 ? 229.539 170.033 199.677 1.00 68.28  ? 482 LYS A CB  1 
ATOM   2116 C CG  . LYS A 1 482 ? 228.112 169.975 199.139 1.00 65.20  ? 482 LYS A CG  1 
ATOM   2117 C CD  . LYS A 1 482 ? 227.089 170.263 200.223 1.00 71.57  ? 482 LYS A CD  1 
ATOM   2118 C CE  . LYS A 1 482 ? 227.223 171.683 200.741 1.00 65.97  ? 482 LYS A CE  1 
ATOM   2119 N NZ  . LYS A 1 482 ? 227.098 172.693 199.655 1.00 65.59  ? 482 LYS A NZ  1 
ATOM   2120 N N   . TYR A 1 483 ? 231.212 172.279 198.125 1.00 62.50  ? 483 TYR A N   1 
ATOM   2121 C CA  . TYR A 1 483 ? 231.271 173.488 197.313 1.00 55.82  ? 483 TYR A CA  1 
ATOM   2122 C C   . TYR A 1 483 ? 232.367 173.450 196.259 1.00 62.45  ? 483 TYR A C   1 
ATOM   2123 O O   . TYR A 1 483 ? 232.448 174.370 195.437 1.00 74.61  ? 483 TYR A O   1 
ATOM   2124 C CB  . TYR A 1 483 ? 231.474 174.718 198.200 1.00 54.60  ? 483 TYR A CB  1 
ATOM   2125 C CG  . TYR A 1 483 ? 230.252 175.104 198.994 1.00 53.01  ? 483 TYR A CG  1 
ATOM   2126 C CD1 . TYR A 1 483 ? 229.064 175.437 198.359 1.00 56.83  ? 483 TYR A CD1 1 
ATOM   2127 C CD2 . TYR A 1 483 ? 230.282 175.124 200.380 1.00 55.68  ? 483 TYR A CD2 1 
ATOM   2128 C CE1 . TYR A 1 483 ? 227.944 175.790 199.082 1.00 58.14  ? 483 TYR A CE1 1 
ATOM   2129 C CE2 . TYR A 1 483 ? 229.167 175.472 201.112 1.00 59.30  ? 483 TYR A CE2 1 
ATOM   2130 C CZ  . TYR A 1 483 ? 228.001 175.805 200.460 1.00 59.37  ? 483 TYR A CZ  1 
ATOM   2131 O OH  . TYR A 1 483 ? 226.888 176.153 201.191 1.00 65.28  ? 483 TYR A OH  1 
ATOM   2132 N N   . SER A 1 484 ? 233.223 172.430 196.280 1.00 70.98  ? 484 SER A N   1 
ATOM   2133 C CA  . SER A 1 484 ? 234.293 172.306 195.302 1.00 67.95  ? 484 SER A CA  1 
ATOM   2134 C C   . SER A 1 484 ? 233.930 171.380 194.150 1.00 63.04  ? 484 SER A C   1 
ATOM   2135 O O   . SER A 1 484 ? 234.471 171.523 193.048 1.00 60.31  ? 484 SER A O   1 
ATOM   2136 C CB  . SER A 1 484 ? 235.569 171.812 195.988 1.00 72.48  ? 484 SER A CB  1 
ATOM   2137 O OG  . SER A 1 484 ? 236.556 171.461 195.036 1.00 80.12  ? 484 SER A OG  1 
ATOM   2138 N N   . THR A 1 485 ? 233.029 170.424 194.389 1.00 65.15  ? 485 THR A N   1 
ATOM   2139 C CA  . THR A 1 485 ? 232.613 169.525 193.316 1.00 68.92  ? 485 THR A CA  1 
ATOM   2140 C C   . THR A 1 485 ? 231.966 170.282 192.161 1.00 70.75  ? 485 THR A C   1 
ATOM   2141 O O   . THR A 1 485 ? 232.053 169.847 191.006 1.00 77.10  ? 485 THR A O   1 
ATOM   2142 C CB  . THR A 1 485 ? 231.664 168.455 193.861 1.00 65.54  ? 485 THR A CB  1 
ATOM   2143 O OG1 . THR A 1 485 ? 231.399 167.481 192.843 1.00 69.81  ? 485 THR A OG1 1 
ATOM   2144 C CG2 . THR A 1 485 ? 230.360 169.072 194.338 1.00 65.18  ? 485 THR A CG2 1 
ATOM   2145 N N   . THR A 1 486 ? 231.339 171.426 192.440 1.00 65.46  ? 486 THR A N   1 
ATOM   2146 C CA  . THR A 1 486 ? 230.680 172.194 191.391 1.00 68.34  ? 486 THR A CA  1 
ATOM   2147 C C   . THR A 1 486 ? 231.661 172.920 190.476 1.00 74.10  ? 486 THR A C   1 
ATOM   2148 O O   . THR A 1 486 ? 231.333 173.143 189.303 1.00 81.30  ? 486 THR A O   1 
ATOM   2149 C CB  . THR A 1 486 ? 229.695 173.189 192.009 1.00 70.16  ? 486 THR A CB  1 
ATOM   2150 O OG1 . THR A 1 486 ? 229.215 174.089 191.002 1.00 73.69  ? 486 THR A OG1 1 
ATOM   2151 C CG2 . THR A 1 486 ? 230.358 173.965 193.121 1.00 70.80  ? 486 THR A CG2 1 
ATOM   2152 N N   . PHE A 1 487 ? 232.851 173.285 190.968 1.00 70.57  ? 487 PHE A N   1 
ATOM   2153 C CA  . PHE A 1 487 ? 233.883 173.785 190.063 1.00 73.50  ? 487 PHE A CA  1 
ATOM   2154 C C   . PHE A 1 487 ? 234.194 172.764 188.982 1.00 72.10  ? 487 PHE A C   1 
ATOM   2155 O O   . PHE A 1 487 ? 234.229 173.096 187.795 1.00 69.11  ? 487 PHE A O   1 
ATOM   2156 C CB  . PHE A 1 487 ? 235.165 174.146 190.817 1.00 68.61  ? 487 PHE A CB  1 
ATOM   2157 C CG  . PHE A 1 487 ? 234.963 175.106 191.943 1.00 68.95  ? 487 PHE A CG  1 
ATOM   2158 C CD1 . PHE A 1 487 ? 234.578 176.409 191.692 1.00 75.84  ? 487 PHE A CD1 1 
ATOM   2159 C CD2 . PHE A 1 487 ? 235.210 174.724 193.245 1.00 71.09  ? 487 PHE A CD2 1 
ATOM   2160 C CE1 . PHE A 1 487 ? 234.404 177.301 192.720 1.00 77.68  ? 487 PHE A CE1 1 
ATOM   2161 C CE2 . PHE A 1 487 ? 235.041 175.608 194.282 1.00 78.98  ? 487 PHE A CE2 1 
ATOM   2162 C CZ  . PHE A 1 487 ? 234.639 176.898 194.021 1.00 76.00  ? 487 PHE A CZ  1 
ATOM   2163 N N   . PHE A 1 488 ? 234.429 171.513 189.376 1.00 73.33  ? 488 PHE A N   1 
ATOM   2164 C CA  . PHE A 1 488 ? 234.721 170.485 188.387 1.00 75.48  ? 488 PHE A CA  1 
ATOM   2165 C C   . PHE A 1 488 ? 233.497 170.164 187.541 1.00 71.04  ? 488 PHE A C   1 
ATOM   2166 O O   . PHE A 1 488 ? 233.635 169.862 186.352 1.00 80.73  ? 488 PHE A O   1 
ATOM   2167 C CB  . PHE A 1 488 ? 235.255 169.235 189.081 1.00 75.82  ? 488 PHE A CB  1 
ATOM   2168 C CG  . PHE A 1 488 ? 236.440 169.497 189.963 1.00 75.74  ? 488 PHE A CG  1 
ATOM   2169 C CD1 . PHE A 1 488 ? 237.424 170.392 189.574 1.00 73.90  ? 488 PHE A CD1 1 
ATOM   2170 C CD2 . PHE A 1 488 ? 236.569 168.856 191.184 1.00 75.09  ? 488 PHE A CD2 1 
ATOM   2171 C CE1 . PHE A 1 488 ? 238.515 170.641 190.382 1.00 73.64  ? 488 PHE A CE1 1 
ATOM   2172 C CE2 . PHE A 1 488 ? 237.660 169.102 191.998 1.00 75.89  ? 488 PHE A CE2 1 
ATOM   2173 C CZ  . PHE A 1 488 ? 238.633 169.995 191.595 1.00 76.19  ? 488 PHE A CZ  1 
ATOM   2174 N N   . MET A 1 489 ? 232.302 170.227 188.131 1.00 64.24  ? 489 MET A N   1 
ATOM   2175 C CA  . MET A 1 489 ? 231.067 170.150 187.356 1.00 71.89  ? 489 MET A CA  1 
ATOM   2176 C C   . MET A 1 489 ? 231.080 171.112 186.173 1.00 78.19  ? 489 MET A C   1 
ATOM   2177 O O   . MET A 1 489 ? 231.010 170.695 185.010 1.00 82.70  ? 489 MET A O   1 
ATOM   2178 C CB  . MET A 1 489 ? 229.870 170.443 188.262 1.00 75.89  ? 489 MET A CB  1 
ATOM   2179 C CG  . MET A 1 489 ? 228.533 170.270 187.578 1.00 77.83  ? 489 MET A CG  1 
ATOM   2180 S SD  . MET A 1 489 ? 228.163 168.560 187.184 1.00 81.61  ? 489 MET A SD  1 
ATOM   2181 C CE  . MET A 1 489 ? 226.576 168.753 186.380 1.00 74.46  ? 489 MET A CE  1 
ATOM   2182 N N   . VAL A 1 490 ? 231.172 172.411 186.461 1.00 80.14  ? 490 VAL A N   1 
ATOM   2183 C CA  . VAL A 1 490 ? 231.085 173.404 185.394 1.00 79.09  ? 490 VAL A CA  1 
ATOM   2184 C C   . VAL A 1 490 ? 232.309 173.334 184.487 1.00 82.93  ? 490 VAL A C   1 
ATOM   2185 O O   . VAL A 1 490 ? 232.204 173.572 183.277 1.00 86.25  ? 490 VAL A O   1 
ATOM   2186 C CB  . VAL A 1 490 ? 230.878 174.814 185.980 1.00 75.06  ? 490 VAL A CB  1 
ATOM   2187 C CG1 . VAL A 1 490 ? 231.976 175.151 186.957 1.00 78.98  ? 490 VAL A CG1 1 
ATOM   2188 C CG2 . VAL A 1 490 ? 230.795 175.856 184.871 1.00 79.43  ? 490 VAL A CG2 1 
ATOM   2189 N N   . THR A 1 491 ? 233.472 172.951 185.028 1.00 80.14  ? 491 THR A N   1 
ATOM   2190 C CA  . THR A 1 491 ? 234.675 172.810 184.200 1.00 81.73  ? 491 THR A CA  1 
ATOM   2191 C C   . THR A 1 491 ? 234.392 171.780 183.152 1.00 82.96  ? 491 THR A C   1 
ATOM   2192 O O   . THR A 1 491 ? 234.462 172.062 181.961 1.00 86.29  ? 491 THR A O   1 
ATOM   2193 C CB  . THR A 1 491 ? 235.906 172.287 184.965 1.00 82.47  ? 491 THR A CB  1 
ATOM   2194 O OG1 . THR A 1 491 ? 236.197 173.132 186.078 1.00 81.00  ? 491 THR A OG1 1 
ATOM   2195 C CG2 . THR A 1 491 ? 237.129 172.253 184.056 1.00 83.89  ? 491 THR A CG2 1 
ATOM   2196 N N   . PHE A 1 492 ? 234.060 170.580 183.598 1.00 81.85  ? 492 PHE A N   1 
ATOM   2197 C CA  . PHE A 1 492 ? 233.828 169.494 182.657 1.00 81.66  ? 492 PHE A CA  1 
ATOM   2198 C C   . PHE A 1 492 ? 232.720 169.848 181.677 1.00 84.35  ? 492 PHE A C   1 
ATOM   2199 O O   . PHE A 1 492 ? 232.828 169.552 180.484 1.00 90.27  ? 492 PHE A O   1 
ATOM   2200 C CB  . PHE A 1 492 ? 233.498 168.206 183.410 1.00 81.53  ? 492 PHE A CB  1 
ATOM   2201 C CG  . PHE A 1 492 ? 234.682 167.591 184.101 1.00 83.78  ? 492 PHE A CG  1 
ATOM   2202 C CD1 . PHE A 1 492 ? 235.957 167.746 183.583 1.00 83.47  ? 492 PHE A CD1 1 
ATOM   2203 C CD2 . PHE A 1 492 ? 234.522 166.862 185.267 1.00 84.58  ? 492 PHE A CD2 1 
ATOM   2204 C CE1 . PHE A 1 492 ? 237.050 167.184 184.214 1.00 84.66  ? 492 PHE A CE1 1 
ATOM   2205 C CE2 . PHE A 1 492 ? 235.612 166.298 185.902 1.00 83.12  ? 492 PHE A CE2 1 
ATOM   2206 C CZ  . PHE A 1 492 ? 236.877 166.459 185.375 1.00 84.80  ? 492 PHE A CZ  1 
ATOM   2207 N N   . ALA A 1 493 ? 231.659 170.505 182.153 1.00 86.98  ? 493 ALA A N   1 
ATOM   2208 C CA  . ALA A 1 493 ? 230.566 170.876 181.260 1.00 90.76  ? 493 ALA A CA  1 
ATOM   2209 C C   . ALA A 1 493 ? 231.051 171.793 180.143 1.00 91.51  ? 493 ALA A C   1 
ATOM   2210 O O   . ALA A 1 493 ? 230.840 171.514 178.957 1.00 93.01  ? 493 ALA A O   1 
ATOM   2211 C CB  . ALA A 1 493 ? 229.444 171.543 182.056 1.00 93.10  ? 493 ALA A CB  1 
ATOM   2212 N N   . ALA A 1 494 ? 231.730 172.885 180.504 1.00 93.13  ? 494 ALA A N   1 
ATOM   2213 C CA  . ALA A 1 494 ? 232.187 173.841 179.500 1.00 96.63  ? 494 ALA A CA  1 
ATOM   2214 C C   . ALA A 1 494 ? 233.255 173.238 178.596 1.00 99.76  ? 494 ALA A C   1 
ATOM   2215 O O   . ALA A 1 494 ? 233.240 173.455 177.376 1.00 104.00 ? 494 ALA A O   1 
ATOM   2216 C CB  . ALA A 1 494 ? 232.710 175.105 180.182 1.00 95.87  ? 494 ALA A CB  1 
ATOM   2217 N N   . LEU A 1 495 ? 234.197 172.486 179.172 1.00 104.70 ? 495 LEU A N   1 
ATOM   2218 C CA  . LEU A 1 495 ? 235.263 171.904 178.368 1.00 106.57 ? 495 LEU A CA  1 
ATOM   2219 C C   . LEU A 1 495 ? 234.710 170.879 177.386 1.00 105.78 ? 495 LEU A C   1 
ATOM   2220 O O   . LEU A 1 495 ? 235.136 170.835 176.229 1.00 108.35 ? 495 LEU A O   1 
ATOM   2221 C CB  . LEU A 1 495 ? 236.329 171.299 179.287 1.00 106.82 ? 495 LEU A CB  1 
ATOM   2222 C CG  . LEU A 1 495 ? 237.385 170.313 178.782 1.00 107.11 ? 495 LEU A CG  1 
ATOM   2223 C CD1 . LEU A 1 495 ? 238.592 170.359 179.700 1.00 107.90 ? 495 LEU A CD1 1 
ATOM   2224 C CD2 . LEU A 1 495 ? 236.839 168.901 178.741 1.00 105.34 ? 495 LEU A CD2 1 
ATOM   2225 N N   . TYR A 1 496 ? 233.754 170.053 177.823 1.00 108.48 ? 496 TYR A N   1 
ATOM   2226 C CA  . TYR A 1 496 ? 233.105 169.118 176.913 1.00 109.22 ? 496 TYR A CA  1 
ATOM   2227 C C   . TYR A 1 496 ? 232.281 169.844 175.861 1.00 108.87 ? 496 TYR A C   1 
ATOM   2228 O O   . TYR A 1 496 ? 232.192 169.380 174.720 1.00 111.86 ? 496 TYR A O   1 
ATOM   2229 C CB  . TYR A 1 496 ? 232.233 168.143 177.707 1.00 110.69 ? 496 TYR A CB  1 
ATOM   2230 C CG  . TYR A 1 496 ? 230.985 167.685 176.985 1.00 112.51 ? 496 TYR A CG  1 
ATOM   2231 C CD1 . TYR A 1 496 ? 231.026 166.624 176.092 1.00 113.76 ? 496 TYR A CD1 1 
ATOM   2232 C CD2 . TYR A 1 496 ? 229.761 168.304 177.209 1.00 112.65 ? 496 TYR A CD2 1 
ATOM   2233 C CE1 . TYR A 1 496 ? 229.888 166.200 175.434 1.00 113.82 ? 496 TYR A CE1 1 
ATOM   2234 C CE2 . TYR A 1 496 ? 228.619 167.888 176.555 1.00 111.70 ? 496 TYR A CE2 1 
ATOM   2235 C CZ  . TYR A 1 496 ? 228.688 166.836 175.669 1.00 113.21 ? 496 TYR A CZ  1 
ATOM   2236 O OH  . TYR A 1 496 ? 227.551 166.417 175.017 1.00 114.67 ? 496 TYR A OH  1 
ATOM   2237 N N   . SER A 1 497 ? 231.675 170.978 176.219 1.00 109.76 ? 497 SER A N   1 
ATOM   2238 C CA  . SER A 1 497 ? 230.955 171.772 175.230 1.00 113.63 ? 497 SER A CA  1 
ATOM   2239 C C   . SER A 1 497 ? 231.888 172.240 174.121 1.00 115.51 ? 497 SER A C   1 
ATOM   2240 O O   . SER A 1 497 ? 231.591 172.077 172.933 1.00 117.22 ? 497 SER A O   1 
ATOM   2241 C CB  . SER A 1 497 ? 230.287 172.965 175.908 1.00 114.83 ? 497 SER A CB  1 
ATOM   2242 O OG  . SER A 1 497 ? 231.088 174.127 175.786 1.00 115.46 ? 497 SER A OG  1 
ATOM   2243 N N   . THR A 1 498 ? 233.034 172.814 174.495 1.00 116.57 ? 498 THR A N   1 
ATOM   2244 C CA  . THR A 1 498 ? 234.002 173.240 173.484 1.00 119.19 ? 498 THR A CA  1 
ATOM   2245 C C   . THR A 1 498 ? 234.562 172.048 172.714 1.00 120.04 ? 498 THR A C   1 
ATOM   2246 O O   . THR A 1 498 ? 234.812 172.142 171.505 1.00 118.18 ? 498 THR A O   1 
ATOM   2247 C CB  . THR A 1 498 ? 235.136 174.042 174.124 1.00 118.97 ? 498 THR A CB  1 
ATOM   2248 O OG1 . THR A 1 498 ? 236.045 173.153 174.786 1.00 120.21 ? 498 THR A OG1 1 
ATOM   2249 C CG2 . THR A 1 498 ? 234.593 175.064 175.111 1.00 117.03 ? 498 THR A CG2 1 
ATOM   2250 N N   . HIS A 1 499 ? 234.765 170.921 173.400 1.00 129.27 ? 499 HIS A N   1 
ATOM   2251 C CA  . HIS A 1 499 ? 235.294 169.726 172.755 1.00 126.92 ? 499 HIS A CA  1 
ATOM   2252 C C   . HIS A 1 499 ? 234.343 169.226 171.675 1.00 127.73 ? 499 HIS A C   1 
ATOM   2253 O O   . HIS A 1 499 ? 234.774 168.844 170.581 1.00 128.73 ? 499 HIS A O   1 
ATOM   2254 C CB  . HIS A 1 499 ? 235.525 168.645 173.813 1.00 128.33 ? 499 HIS A CB  1 
ATOM   2255 C CG  . HIS A 1 499 ? 236.581 167.648 173.453 1.00 126.45 ? 499 HIS A CG  1 
ATOM   2256 N ND1 . HIS A 1 499 ? 237.888 168.008 173.208 1.00 127.95 ? 499 HIS A ND1 1 
ATOM   2257 C CD2 . HIS A 1 499 ? 236.526 166.304 173.303 1.00 126.54 ? 499 HIS A CD2 1 
ATOM   2258 C CE1 . HIS A 1 499 ? 238.594 166.927 172.926 1.00 130.72 ? 499 HIS A CE1 1 
ATOM   2259 N NE2 . HIS A 1 499 ? 237.790 165.881 172.972 1.00 129.28 ? 499 HIS A NE2 1 
ATOM   2260 N N   . LYS A 1 500 ? 233.041 169.220 171.971 1.00 126.18 ? 500 LYS A N   1 
ATOM   2261 C CA  . LYS A 1 500 ? 232.044 168.836 170.978 1.00 126.04 ? 500 LYS A CA  1 
ATOM   2262 C C   . LYS A 1 500 ? 231.929 169.882 169.877 1.00 127.40 ? 500 LYS A C   1 
ATOM   2263 O O   . LYS A 1 500 ? 231.694 169.540 168.712 1.00 127.62 ? 500 LYS A O   1 
ATOM   2264 C CB  . LYS A 1 500 ? 230.691 168.614 171.656 1.00 123.65 ? 500 LYS A CB  1 
ATOM   2265 C CG  . LYS A 1 500 ? 229.568 168.227 170.707 1.00 124.20 ? 500 LYS A CG  1 
ATOM   2266 C CD  . LYS A 1 500 ? 229.682 166.776 170.275 1.00 125.10 ? 500 LYS A CD  1 
ATOM   2267 C CE  . LYS A 1 500 ? 229.197 166.586 168.847 1.00 125.05 ? 500 LYS A CE  1 
ATOM   2268 N NZ  . LYS A 1 500 ? 229.939 167.454 167.890 1.00 125.00 ? 500 LYS A NZ  1 
ATOM   2269 N N   . GLU A 1 501 ? 232.084 171.163 170.225 1.00 133.47 ? 501 GLU A N   1 
ATOM   2270 C CA  . GLU A 1 501 ? 232.039 172.212 169.212 1.00 133.43 ? 501 GLU A CA  1 
ATOM   2271 C C   . GLU A 1 501 ? 233.152 172.034 168.188 1.00 136.40 ? 501 GLU A C   1 
ATOM   2272 O O   . GLU A 1 501 ? 232.924 172.184 166.981 1.00 136.41 ? 501 GLU A O   1 
ATOM   2273 C CB  . GLU A 1 501 ? 232.133 173.589 169.872 1.00 132.09 ? 501 GLU A CB  1 
ATOM   2274 C CG  . GLU A 1 501 ? 230.846 174.053 170.536 1.00 133.76 ? 501 GLU A CG  1 
ATOM   2275 C CD  . GLU A 1 501 ? 231.088 175.101 171.605 1.00 136.18 ? 501 GLU A CD  1 
ATOM   2276 O OE1 . GLU A 1 501 ? 232.243 175.553 171.745 1.00 138.36 ? 501 GLU A OE1 1 
ATOM   2277 O OE2 . GLU A 1 501 ? 230.122 175.473 172.304 1.00 135.69 ? 501 GLU A OE2 1 
ATOM   2278 N N   . ARG A 1 502 ? 234.361 171.714 168.645 1.00 143.68 ? 502 ARG A N   1 
ATOM   2279 C CA  . ARG A 1 502 ? 235.457 171.417 167.733 1.00 142.81 ? 502 ARG A CA  1 
ATOM   2280 C C   . ARG A 1 502 ? 235.512 169.948 167.328 1.00 141.16 ? 502 ARG A C   1 
ATOM   2281 O O   . ARG A 1 502 ? 236.285 169.598 166.429 1.00 140.55 ? 502 ARG A O   1 
ATOM   2282 C CB  . ARG A 1 502 ? 236.792 171.840 168.351 1.00 141.66 ? 502 ARG A CB  1 
ATOM   2283 C CG  . ARG A 1 502 ? 236.852 173.306 168.749 1.00 142.20 ? 502 ARG A CG  1 
ATOM   2284 C CD  . ARG A 1 502 ? 238.058 173.595 169.629 1.00 141.68 ? 502 ARG A CD  1 
ATOM   2285 N NE  . ARG A 1 502 ? 238.039 174.957 170.150 1.00 142.01 ? 502 ARG A NE  1 
ATOM   2286 C CZ  . ARG A 1 502 ? 238.964 175.466 170.952 1.00 141.70 ? 502 ARG A CZ  1 
ATOM   2287 N NH1 . ARG A 1 502 ? 240.004 174.751 171.350 1.00 141.87 ? 502 ARG A NH1 1 
ATOM   2288 N NH2 . ARG A 1 502 ? 238.842 176.724 171.367 1.00 139.82 ? 502 ARG A NH2 1 
ATOM   2289 N N   . GLY A 1 503 ? 234.716 169.088 167.962 1.00 138.86 ? 503 GLY A N   1 
ATOM   2290 C CA  . GLY A 1 503 ? 234.497 167.734 167.487 1.00 137.80 ? 503 GLY A CA  1 
ATOM   2291 C C   . GLY A 1 503 ? 235.675 166.778 167.470 1.00 139.00 ? 503 GLY A C   1 
ATOM   2292 O O   . GLY A 1 503 ? 235.897 166.100 166.463 1.00 140.00 ? 503 GLY A O   1 
ATOM   2293 N N   . HIS A 1 504 ? 236.437 166.703 168.559 1.00 136.89 ? 504 HIS A N   1 
ATOM   2294 C CA  . HIS A 1 504 ? 237.479 165.689 168.671 1.00 136.54 ? 504 HIS A CA  1 
ATOM   2295 C C   . HIS A 1 504 ? 236.856 164.357 169.091 1.00 135.83 ? 504 HIS A C   1 
ATOM   2296 O O   . HIS A 1 504 ? 235.635 164.182 169.088 1.00 134.87 ? 504 HIS A O   1 
ATOM   2297 C CB  . HIS A 1 504 ? 238.576 166.129 169.638 1.00 135.77 ? 504 HIS A CB  1 
ATOM   2298 C CG  . HIS A 1 504 ? 238.788 167.609 169.697 1.00 137.13 ? 504 HIS A CG  1 
ATOM   2299 N ND1 . HIS A 1 504 ? 237.924 168.462 170.349 1.00 138.06 ? 504 HIS A ND1 1 
ATOM   2300 C CD2 . HIS A 1 504 ? 239.778 168.387 169.197 1.00 135.90 ? 504 HIS A CD2 1 
ATOM   2301 C CE1 . HIS A 1 504 ? 238.372 169.700 170.249 1.00 136.18 ? 504 HIS A CE1 1 
ATOM   2302 N NE2 . HIS A 1 504 ? 239.492 169.683 169.550 1.00 136.73 ? 504 HIS A NE2 1 
ATOM   2303 N N   . SER A 1 505 ? 237.703 163.393 169.464 1.00 135.01 ? 505 SER A N   1 
ATOM   2304 C CA  . SER A 1 505 ? 237.224 162.042 169.741 1.00 136.02 ? 505 SER A CA  1 
ATOM   2305 C C   . SER A 1 505 ? 236.933 161.809 171.220 1.00 137.07 ? 505 SER A C   1 
ATOM   2306 O O   . SER A 1 505 ? 236.147 160.915 171.553 1.00 137.31 ? 505 SER A O   1 
ATOM   2307 C CB  . SER A 1 505 ? 238.243 161.014 169.246 1.00 135.24 ? 505 SER A CB  1 
ATOM   2308 O OG  . SER A 1 505 ? 239.414 161.032 170.044 1.00 134.17 ? 505 SER A OG  1 
ATOM   2309 N N   . ASP A 1 506 ? 237.543 162.587 172.116 1.00 135.63 ? 506 ASP A N   1 
ATOM   2310 C CA  . ASP A 1 506 ? 237.349 162.411 173.551 1.00 134.85 ? 506 ASP A CA  1 
ATOM   2311 C C   . ASP A 1 506 ? 236.047 163.029 174.057 1.00 132.29 ? 506 ASP A C   1 
ATOM   2312 O O   . ASP A 1 506 ? 235.864 163.157 175.277 1.00 129.82 ? 506 ASP A O   1 
ATOM   2313 C CB  . ASP A 1 506 ? 238.537 162.996 174.319 1.00 134.30 ? 506 ASP A CB  1 
ATOM   2314 C CG  . ASP A 1 506 ? 239.870 162.485 173.809 1.00 134.38 ? 506 ASP A CG  1 
ATOM   2315 O OD1 . ASP A 1 506 ? 239.872 161.648 172.881 1.00 134.40 ? 506 ASP A OD1 1 
ATOM   2316 O OD2 . ASP A 1 506 ? 240.916 162.920 174.335 1.00 133.61 ? 506 ASP A OD2 1 
ATOM   2317 N N   . THR A 1 507 ? 235.149 163.409 173.145 1.00 128.13 ? 507 THR A N   1 
ATOM   2318 C CA  . THR A 1 507 ? 233.894 164.036 173.544 1.00 128.48 ? 507 THR A CA  1 
ATOM   2319 C C   . THR A 1 507 ? 233.049 163.090 174.388 1.00 129.50 ? 507 THR A C   1 
ATOM   2320 O O   . THR A 1 507 ? 232.503 163.486 175.422 1.00 131.07 ? 507 THR A O   1 
ATOM   2321 C CB  . THR A 1 507 ? 233.123 164.495 172.304 1.00 127.83 ? 507 THR A CB  1 
ATOM   2322 O OG1 . THR A 1 507 ? 233.732 165.679 171.774 1.00 127.61 ? 507 THR A OG1 1 
ATOM   2323 C CG2 . THR A 1 507 ? 231.671 164.789 172.648 1.00 126.77 ? 507 THR A CG2 1 
ATOM   2324 N N   . MET A 1 508 ? 232.942 161.826 173.969 1.00 124.78 ? 508 MET A N   1 
ATOM   2325 C CA  . MET A 1 508 ? 232.147 160.863 174.727 1.00 123.74 ? 508 MET A CA  1 
ATOM   2326 C C   . MET A 1 508 ? 232.766 160.574 176.089 1.00 122.78 ? 508 MET A C   1 
ATOM   2327 O O   . MET A 1 508 ? 232.049 160.450 177.090 1.00 122.86 ? 508 MET A O   1 
ATOM   2328 C CB  . MET A 1 508 ? 231.982 159.570 173.926 1.00 123.42 ? 508 MET A CB  1 
ATOM   2329 C CG  . MET A 1 508 ? 230.585 158.935 173.975 1.00 123.79 ? 508 MET A CG  1 
ATOM   2330 S SD  . MET A 1 508 ? 229.122 160.007 174.027 1.00 126.36 ? 508 MET A SD  1 
ATOM   2331 C CE  . MET A 1 508 ? 229.442 161.210 172.731 1.00 123.26 ? 508 MET A CE  1 
ATOM   2332 N N   . VAL A 1 509 ? 234.095 160.463 176.148 1.00 123.86 ? 509 VAL A N   1 
ATOM   2333 C CA  . VAL A 1 509 ? 234.765 160.206 177.421 1.00 126.25 ? 509 VAL A CA  1 
ATOM   2334 C C   . VAL A 1 509 ? 234.528 161.362 178.386 1.00 126.83 ? 509 VAL A C   1 
ATOM   2335 O O   . VAL A 1 509 ? 234.228 161.160 179.571 1.00 124.77 ? 509 VAL A O   1 
ATOM   2336 C CB  . VAL A 1 509 ? 236.268 159.959 177.197 1.00 125.70 ? 509 VAL A CB  1 
ATOM   2337 C CG1 . VAL A 1 509 ? 236.976 159.749 178.526 1.00 124.66 ? 509 VAL A CG1 1 
ATOM   2338 C CG2 . VAL A 1 509 ? 236.478 158.765 176.278 1.00 124.48 ? 509 VAL A CG2 1 
ATOM   2339 N N   . PHE A 1 510 ? 234.647 162.595 177.890 1.00 123.62 ? 510 PHE A N   1 
ATOM   2340 C CA  . PHE A 1 510 ? 234.457 163.740 178.769 1.00 121.94 ? 510 PHE A CA  1 
ATOM   2341 C C   . PHE A 1 510 ? 232.989 163.923 179.135 1.00 119.21 ? 510 PHE A C   1 
ATOM   2342 O O   . PHE A 1 510 ? 232.683 164.412 180.226 1.00 120.13 ? 510 PHE A O   1 
ATOM   2343 C CB  . PHE A 1 510 ? 235.031 164.996 178.118 1.00 119.85 ? 510 PHE A CB  1 
ATOM   2344 C CG  . PHE A 1 510 ? 236.348 165.420 178.701 1.00 121.72 ? 510 PHE A CG  1 
ATOM   2345 C CD1 . PHE A 1 510 ? 236.487 165.617 180.066 1.00 121.85 ? 510 PHE A CD1 1 
ATOM   2346 C CD2 . PHE A 1 510 ? 237.458 165.584 177.889 1.00 122.32 ? 510 PHE A CD2 1 
ATOM   2347 C CE1 . PHE A 1 510 ? 237.703 165.994 180.606 1.00 120.40 ? 510 PHE A CE1 1 
ATOM   2348 C CE2 . PHE A 1 510 ? 238.677 165.959 178.423 1.00 123.06 ? 510 PHE A CE2 1 
ATOM   2349 C CZ  . PHE A 1 510 ? 238.800 166.165 179.783 1.00 121.43 ? 510 PHE A CZ  1 
ATOM   2350 N N   . PHE A 1 511 ? 232.071 163.515 178.256 1.00 109.31 ? 511 PHE A N   1 
ATOM   2351 C CA  . PHE A 1 511 ? 230.656 163.496 178.614 1.00 108.87 ? 511 PHE A CA  1 
ATOM   2352 C C   . PHE A 1 511 ? 230.389 162.499 179.735 1.00 110.87 ? 511 PHE A C   1 
ATOM   2353 O O   . PHE A 1 511 ? 229.605 162.776 180.650 1.00 111.03 ? 511 PHE A O   1 
ATOM   2354 C CB  . PHE A 1 511 ? 229.811 163.165 177.383 1.00 109.85 ? 511 PHE A CB  1 
ATOM   2355 C CG  . PHE A 1 511 ? 228.331 163.137 177.646 1.00 108.55 ? 511 PHE A CG  1 
ATOM   2356 C CD1 . PHE A 1 511 ? 227.568 164.283 177.504 1.00 107.93 ? 511 PHE A CD1 1 
ATOM   2357 C CD2 . PHE A 1 511 ? 227.700 161.963 178.028 1.00 108.99 ? 511 PHE A CD2 1 
ATOM   2358 C CE1 . PHE A 1 511 ? 226.207 164.262 177.742 1.00 110.33 ? 511 PHE A CE1 1 
ATOM   2359 C CE2 . PHE A 1 511 ? 226.341 161.936 178.268 1.00 108.91 ? 511 PHE A CE2 1 
ATOM   2360 C CZ  . PHE A 1 511 ? 225.593 163.086 178.125 1.00 110.15 ? 511 PHE A CZ  1 
ATOM   2361 N N   . TYR A 1 512 ? 231.021 161.325 179.672 1.00 116.96 ? 512 TYR A N   1 
ATOM   2362 C CA  . TYR A 1 512 ? 230.885 160.356 180.756 1.00 117.81 ? 512 TYR A CA  1 
ATOM   2363 C C   . TYR A 1 512 ? 231.448 160.910 182.059 1.00 119.36 ? 512 TYR A C   1 
ATOM   2364 O O   . TYR A 1 512 ? 230.846 160.743 183.128 1.00 118.99 ? 512 TYR A O   1 
ATOM   2365 C CB  . TYR A 1 512 ? 231.582 159.047 180.383 1.00 118.21 ? 512 TYR A CB  1 
ATOM   2366 C CG  . TYR A 1 512 ? 231.230 157.883 181.284 1.00 120.30 ? 512 TYR A CG  1 
ATOM   2367 C CD1 . TYR A 1 512 ? 229.986 157.802 181.895 1.00 118.92 ? 512 TYR A CD1 1 
ATOM   2368 C CD2 . TYR A 1 512 ? 232.144 156.865 181.522 1.00 118.95 ? 512 TYR A CD2 1 
ATOM   2369 C CE1 . TYR A 1 512 ? 229.662 156.740 182.719 1.00 117.64 ? 512 TYR A CE1 1 
ATOM   2370 C CE2 . TYR A 1 512 ? 231.829 155.799 182.344 1.00 119.85 ? 512 TYR A CE2 1 
ATOM   2371 C CZ  . TYR A 1 512 ? 230.587 155.741 182.940 1.00 120.44 ? 512 TYR A CZ  1 
ATOM   2372 O OH  . TYR A 1 512 ? 230.268 154.682 183.759 1.00 120.26 ? 512 TYR A OH  1 
ATOM   2373 N N   . LEU A 1 513 ? 232.602 161.576 181.987 1.00 108.42 ? 513 LEU A N   1 
ATOM   2374 C CA  . LEU A 1 513 ? 233.167 162.204 183.179 1.00 106.70 ? 513 LEU A CA  1 
ATOM   2375 C C   . LEU A 1 513 ? 232.218 163.256 183.744 1.00 105.56 ? 513 LEU A C   1 
ATOM   2376 O O   . LEU A 1 513 ? 232.007 163.333 184.963 1.00 104.68 ? 513 LEU A O   1 
ATOM   2377 C CB  . LEU A 1 513 ? 234.524 162.826 182.852 1.00 105.04 ? 513 LEU A CB  1 
ATOM   2378 C CG  . LEU A 1 513 ? 235.765 162.078 183.343 1.00 107.25 ? 513 LEU A CG  1 
ATOM   2379 C CD1 . LEU A 1 513 ? 237.014 162.922 183.138 1.00 106.84 ? 513 LEU A CD1 1 
ATOM   2380 C CD2 . LEU A 1 513 ? 235.615 161.682 184.803 1.00 106.14 ? 513 LEU A CD2 1 
ATOM   2381 N N   . TRP A 1 514 ? 231.621 164.063 182.867 1.00 97.77  ? 514 TRP A N   1 
ATOM   2382 C CA  . TRP A 1 514 ? 230.712 165.103 183.322 1.00 94.69  ? 514 TRP A CA  1 
ATOM   2383 C C   . TRP A 1 514 ? 229.438 164.518 183.915 1.00 93.32  ? 514 TRP A C   1 
ATOM   2384 O O   . TRP A 1 514 ? 228.905 165.076 184.874 1.00 97.10  ? 514 TRP A O   1 
ATOM   2385 C CB  . TRP A 1 514 ? 230.414 166.069 182.171 1.00 96.26  ? 514 TRP A CB  1 
ATOM   2386 C CG  . TRP A 1 514 ? 229.135 166.845 182.294 1.00 94.74  ? 514 TRP A CG  1 
ATOM   2387 C CD1 . TRP A 1 514 ? 229.003 168.134 182.718 1.00 96.27  ? 514 TRP A CD1 1 
ATOM   2388 C CD2 . TRP A 1 514 ? 227.825 166.417 181.901 1.00 96.47  ? 514 TRP A CD2 1 
ATOM   2389 N NE1 . TRP A 1 514 ? 227.686 168.519 182.664 1.00 97.81  ? 514 TRP A NE1 1 
ATOM   2390 C CE2 . TRP A 1 514 ? 226.942 167.484 182.160 1.00 96.95  ? 514 TRP A CE2 1 
ATOM   2391 C CE3 . TRP A 1 514 ? 227.309 165.229 181.376 1.00 97.11  ? 514 TRP A CE3 1 
ATOM   2392 C CZ2 . TRP A 1 514 ? 225.575 167.399 181.912 1.00 95.87  ? 514 TRP A CZ2 1 
ATOM   2393 C CZ3 . TRP A 1 514 ? 225.952 165.147 181.130 1.00 97.38  ? 514 TRP A CZ3 1 
ATOM   2394 C CH2 . TRP A 1 514 ? 225.100 166.225 181.400 1.00 94.84  ? 514 TRP A CH2 1 
ATOM   2395 N N   . ILE A 1 515 ? 228.947 163.390 183.393 1.00 89.96  ? 515 ILE A N   1 
ATOM   2396 C CA  . ILE A 1 515 ? 227.735 162.799 183.960 1.00 91.46  ? 515 ILE A CA  1 
ATOM   2397 C C   . ILE A 1 515 ? 228.022 162.144 185.312 1.00 92.40  ? 515 ILE A C   1 
ATOM   2398 O O   . ILE A 1 515 ? 227.199 162.221 186.235 1.00 92.36  ? 515 ILE A O   1 
ATOM   2399 C CB  . ILE A 1 515 ? 227.072 161.821 182.966 1.00 96.49  ? 515 ILE A CB  1 
ATOM   2400 C CG1 . ILE A 1 515 ? 225.627 161.532 183.383 1.00 97.23  ? 515 ILE A CG1 1 
ATOM   2401 C CG2 . ILE A 1 515 ? 227.829 160.514 182.856 1.00 97.44  ? 515 ILE A CG2 1 
ATOM   2402 C CD1 . ILE A 1 515 ? 224.662 162.662 183.118 1.00 91.99  ? 515 ILE A CD1 1 
ATOM   2403 N N   . VAL A 1 516 ? 229.185 161.501 185.471 1.00 87.56  ? 516 VAL A N   1 
ATOM   2404 C CA  . VAL A 1 516 ? 229.467 160.908 186.778 1.00 89.01  ? 516 VAL A CA  1 
ATOM   2405 C C   . VAL A 1 516 ? 229.692 162.006 187.813 1.00 88.63  ? 516 VAL A C   1 
ATOM   2406 O O   . VAL A 1 516 ? 229.258 161.890 188.969 1.00 87.47  ? 516 VAL A O   1 
ATOM   2407 C CB  . VAL A 1 516 ? 230.652 159.921 186.721 1.00 91.39  ? 516 VAL A CB  1 
ATOM   2408 C CG1 . VAL A 1 516 ? 231.829 160.497 185.982 1.00 89.56  ? 516 VAL A CG1 1 
ATOM   2409 C CG2 . VAL A 1 516 ? 231.061 159.481 188.123 1.00 89.49  ? 516 VAL A CG2 1 
ATOM   2410 N N   . PHE A 1 517 ? 230.344 163.105 187.413 1.00 86.28  ? 517 PHE A N   1 
ATOM   2411 C CA  . PHE A 1 517 ? 230.519 164.209 188.351 1.00 83.79  ? 517 PHE A CA  1 
ATOM   2412 C C   . PHE A 1 517 ? 229.196 164.911 188.641 1.00 80.31  ? 517 PHE A C   1 
ATOM   2413 O O   . PHE A 1 517 ? 228.963 165.336 189.775 1.00 79.78  ? 517 PHE A O   1 
ATOM   2414 C CB  . PHE A 1 517 ? 231.566 165.188 187.827 1.00 85.60  ? 517 PHE A CB  1 
ATOM   2415 C CG  . PHE A 1 517 ? 232.918 165.001 188.453 1.00 86.16  ? 517 PHE A CG  1 
ATOM   2416 C CD1 . PHE A 1 517 ? 233.378 163.729 188.754 1.00 86.37  ? 517 PHE A CD1 1 
ATOM   2417 C CD2 . PHE A 1 517 ? 233.722 166.084 188.753 1.00 83.07  ? 517 PHE A CD2 1 
ATOM   2418 C CE1 . PHE A 1 517 ? 234.617 163.541 189.334 1.00 88.35  ? 517 PHE A CE1 1 
ATOM   2419 C CE2 . PHE A 1 517 ? 234.964 165.899 189.334 1.00 82.15  ? 517 PHE A CE2 1 
ATOM   2420 C CZ  . PHE A 1 517 ? 235.410 164.629 189.624 1.00 86.67  ? 517 PHE A CZ  1 
ATOM   2421 N N   . TYR A 1 518 ? 228.333 165.047 187.631 1.00 74.18  ? 518 TYR A N   1 
ATOM   2422 C CA  . TYR A 1 518 ? 226.930 165.394 187.834 1.00 68.65  ? 518 TYR A CA  1 
ATOM   2423 C C   . TYR A 1 518 ? 226.321 164.597 188.976 1.00 69.85  ? 518 TYR A C   1 
ATOM   2424 O O   . TYR A 1 518 ? 225.817 165.166 189.954 1.00 76.63  ? 518 TYR A O   1 
ATOM   2425 C CB  . TYR A 1 518 ? 226.178 165.140 186.521 1.00 75.30  ? 518 TYR A CB  1 
ATOM   2426 C CG  . TYR A 1 518 ? 224.666 165.259 186.543 1.00 74.02  ? 518 TYR A CG  1 
ATOM   2427 C CD1 . TYR A 1 518 ? 223.878 164.227 187.042 1.00 74.91  ? 518 TYR A CD1 1 
ATOM   2428 C CD2 . TYR A 1 518 ? 224.024 166.360 185.997 1.00 75.15  ? 518 TYR A CD2 1 
ATOM   2429 C CE1 . TYR A 1 518 ? 222.504 164.312 187.046 1.00 71.59  ? 518 TYR A CE1 1 
ATOM   2430 C CE2 . TYR A 1 518 ? 222.645 166.449 185.989 1.00 75.98  ? 518 TYR A CE2 1 
ATOM   2431 C CZ  . TYR A 1 518 ? 221.891 165.422 186.518 1.00 71.83  ? 518 TYR A CZ  1 
ATOM   2432 O OH  . TYR A 1 518 ? 220.518 165.498 186.521 1.00 71.46  ? 518 TYR A OH  1 
ATOM   2433 N N   . ILE A 1 519 ? 226.352 163.270 188.855 1.00 67.46  ? 519 ILE A N   1 
ATOM   2434 C CA  . ILE A 1 519 ? 225.668 162.419 189.824 1.00 69.81  ? 519 ILE A CA  1 
ATOM   2435 C C   . ILE A 1 519 ? 226.264 162.609 191.213 1.00 72.77  ? 519 ILE A C   1 
ATOM   2436 O O   . ILE A 1 519 ? 225.537 162.792 192.198 1.00 70.33  ? 519 ILE A O   1 
ATOM   2437 C CB  . ILE A 1 519 ? 225.718 160.947 189.377 1.00 74.70  ? 519 ILE A CB  1 
ATOM   2438 C CG1 . ILE A 1 519 ? 224.549 160.642 188.438 1.00 73.85  ? 519 ILE A CG1 1 
ATOM   2439 C CG2 . ILE A 1 519 ? 225.689 160.013 190.579 1.00 76.55  ? 519 ILE A CG2 1 
ATOM   2440 C CD1 . ILE A 1 519 ? 223.201 160.613 189.128 1.00 68.35  ? 519 ILE A CD1 1 
ATOM   2441 N N   . ILE A 1 520 ? 227.597 162.596 191.313 1.00 74.88  ? 520 ILE A N   1 
ATOM   2442 C CA  . ILE A 1 520 ? 228.217 162.657 192.634 1.00 74.18  ? 520 ILE A CA  1 
ATOM   2443 C C   . ILE A 1 520 ? 227.994 164.023 193.278 1.00 71.24  ? 520 ILE A C   1 
ATOM   2444 O O   . ILE A 1 520 ? 227.705 164.111 194.476 1.00 65.21  ? 520 ILE A O   1 
ATOM   2445 C CB  . ILE A 1 520 ? 229.711 162.285 192.567 1.00 70.21  ? 520 ILE A CB  1 
ATOM   2446 C CG1 . ILE A 1 520 ? 230.483 163.233 191.653 1.00 69.17  ? 520 ILE A CG1 1 
ATOM   2447 C CG2 . ILE A 1 520 ? 229.879 160.842 192.113 1.00 70.35  ? 520 ILE A CG2 1 
ATOM   2448 C CD1 . ILE A 1 520 ? 231.760 163.763 192.259 1.00 65.94  ? 520 ILE A CD1 1 
ATOM   2449 N N   . SER A 1 521 ? 228.108 165.108 192.504 1.00 67.09  ? 521 SER A N   1 
ATOM   2450 C CA  . SER A 1 521 ? 227.901 166.443 193.056 1.00 64.98  ? 521 SER A CA  1 
ATOM   2451 C C   . SER A 1 521 ? 226.463 166.632 193.518 1.00 62.26  ? 521 SER A C   1 
ATOM   2452 O O   . SER A 1 521 ? 226.212 167.154 194.615 1.00 65.19  ? 521 SER A O   1 
ATOM   2453 C CB  . SER A 1 521 ? 228.267 167.498 192.012 1.00 64.46  ? 521 SER A CB  1 
ATOM   2454 O OG  . SER A 1 521 ? 227.501 168.677 192.190 1.00 53.27  ? 521 SER A OG  1 
ATOM   2455 N N   . SER A 1 522 ? 225.500 166.219 192.690 1.00 57.68  ? 522 SER A N   1 
ATOM   2456 C CA  . SER A 1 522 ? 224.103 166.389 193.064 1.00 52.14  ? 522 SER A CA  1 
ATOM   2457 C C   . SER A 1 522 ? 223.756 165.546 194.282 1.00 57.13  ? 522 SER A C   1 
ATOM   2458 O O   . SER A 1 522 ? 223.028 166.002 195.171 1.00 62.27  ? 522 SER A O   1 
ATOM   2459 C CB  . SER A 1 522 ? 223.195 166.043 191.888 1.00 51.59  ? 522 SER A CB  1 
ATOM   2460 O OG  . SER A 1 522 ? 221.839 166.139 192.275 1.00 50.52  ? 522 SER A OG  1 
ATOM   2461 N N   . CYS A 1 523 ? 224.268 164.313 194.346 1.00 66.85  ? 523 CYS A N   1 
ATOM   2462 C CA  . CYS A 1 523 ? 224.025 163.480 195.519 1.00 69.18  ? 523 CYS A CA  1 
ATOM   2463 C C   . CYS A 1 523 ? 224.662 164.084 196.764 1.00 70.02  ? 523 CYS A C   1 
ATOM   2464 O O   . CYS A 1 523 ? 224.051 164.088 197.837 1.00 66.99  ? 523 CYS A O   1 
ATOM   2465 C CB  . CYS A 1 523 ? 224.549 162.065 195.273 1.00 72.44  ? 523 CYS A CB  1 
ATOM   2466 S SG  . CYS A 1 523 ? 223.274 160.874 194.798 1.00 85.30  ? 523 CYS A SG  1 
ATOM   2467 N N   . TYR A 1 524 ? 225.885 164.602 196.638 1.00 68.09  ? 524 TYR A N   1 
ATOM   2468 C CA  . TYR A 1 524 ? 226.560 165.274 197.743 1.00 68.20  ? 524 TYR A CA  1 
ATOM   2469 C C   . TYR A 1 524 ? 225.690 166.393 198.303 1.00 72.03  ? 524 TYR A C   1 
ATOM   2470 O O   . TYR A 1 524 ? 225.404 166.445 199.508 1.00 69.24  ? 524 TYR A O   1 
ATOM   2471 C CB  . TYR A 1 524 ? 227.896 165.822 197.230 1.00 63.67  ? 524 TYR A CB  1 
ATOM   2472 C CG  . TYR A 1 524 ? 228.970 166.102 198.260 1.00 66.75  ? 524 TYR A CG  1 
ATOM   2473 C CD1 . TYR A 1 524 ? 228.674 166.224 199.610 1.00 72.45  ? 524 TYR A CD1 1 
ATOM   2474 C CD2 . TYR A 1 524 ? 230.292 166.262 197.863 1.00 65.25  ? 524 TYR A CD2 1 
ATOM   2475 C CE1 . TYR A 1 524 ? 229.671 166.488 200.536 1.00 75.74  ? 524 TYR A CE1 1 
ATOM   2476 C CE2 . TYR A 1 524 ? 231.289 166.522 198.776 1.00 68.73  ? 524 TYR A CE2 1 
ATOM   2477 C CZ  . TYR A 1 524 ? 230.976 166.635 200.110 1.00 73.47  ? 524 TYR A CZ  1 
ATOM   2478 O OH  . TYR A 1 524 ? 231.977 166.897 201.016 1.00 67.18  ? 524 TYR A OH  1 
ATOM   2479 N N   . THR A 1 525 ? 225.234 167.284 197.418 1.00 64.87  ? 525 THR A N   1 
ATOM   2480 C CA  . THR A 1 525 ? 224.423 168.414 197.859 1.00 52.31  ? 525 THR A CA  1 
ATOM   2481 C C   . THR A 1 525 ? 223.094 167.962 198.452 1.00 51.11  ? 525 THR A C   1 
ATOM   2482 O O   . THR A 1 525 ? 222.673 168.483 199.491 1.00 61.65  ? 525 THR A O   1 
ATOM   2483 C CB  . THR A 1 525 ? 224.181 169.376 196.696 1.00 55.50  ? 525 THR A CB  1 
ATOM   2484 O OG1 . THR A 1 525 ? 224.032 168.632 195.481 1.00 67.19  ? 525 THR A OG1 1 
ATOM   2485 C CG2 . THR A 1 525 ? 225.348 170.340 196.553 1.00 54.58  ? 525 THR A CG2 1 
ATOM   2486 N N   . LEU A 1 526 ? 222.425 166.998 197.814 1.00 42.46  ? 526 LEU A N   1 
ATOM   2487 C CA  . LEU A 1 526 ? 221.123 166.548 198.294 1.00 46.31  ? 526 LEU A CA  1 
ATOM   2488 C C   . LEU A 1 526 ? 221.242 165.928 199.679 1.00 54.78  ? 526 LEU A C   1 
ATOM   2489 O O   . LEU A 1 526 ? 220.447 166.231 200.577 1.00 61.40  ? 526 LEU A O   1 
ATOM   2490 C CB  . LEU A 1 526 ? 220.521 165.560 197.289 1.00 50.95  ? 526 LEU A CB  1 
ATOM   2491 C CG  . LEU A 1 526 ? 219.062 165.077 197.325 1.00 52.89  ? 526 LEU A CG  1 
ATOM   2492 C CD1 . LEU A 1 526 ? 218.779 164.250 196.080 1.00 55.75  ? 526 LEU A CD1 1 
ATOM   2493 C CD2 . LEU A 1 526 ? 218.719 164.261 198.561 1.00 50.84  ? 526 LEU A CD2 1 
ATOM   2494 N N   . ILE A 1 527 ? 222.239 165.063 199.876 1.00 63.86  ? 527 ILE A N   1 
ATOM   2495 C CA  . ILE A 1 527 ? 222.379 164.391 201.162 1.00 62.80  ? 527 ILE A CA  1 
ATOM   2496 C C   . ILE A 1 527 ? 222.784 165.379 202.243 1.00 62.56  ? 527 ILE A C   1 
ATOM   2497 O O   . ILE A 1 527 ? 222.312 165.289 203.382 1.00 59.14  ? 527 ILE A O   1 
ATOM   2498 C CB  . ILE A 1 527 ? 223.369 163.217 201.060 1.00 64.82  ? 527 ILE A CB  1 
ATOM   2499 C CG1 . ILE A 1 527 ? 222.922 162.248 199.969 1.00 63.10  ? 527 ILE A CG1 1 
ATOM   2500 C CG2 . ILE A 1 527 ? 223.456 162.480 202.383 1.00 64.18  ? 527 ILE A CG2 1 
ATOM   2501 C CD1 . ILE A 1 527 ? 224.016 161.305 199.509 1.00 61.14  ? 527 ILE A CD1 1 
ATOM   2502 N N   . TRP A 1 528 ? 223.654 166.342 201.923 1.00 66.49  ? 528 TRP A N   1 
ATOM   2503 C CA  . TRP A 1 528 ? 224.007 167.298 202.967 1.00 63.38  ? 528 TRP A CA  1 
ATOM   2504 C C   . TRP A 1 528 ? 222.807 168.165 203.331 1.00 66.27  ? 528 TRP A C   1 
ATOM   2505 O O   . TRP A 1 528 ? 222.524 168.364 204.517 1.00 66.04  ? 528 TRP A O   1 
ATOM   2506 C CB  . TRP A 1 528 ? 225.217 168.138 202.549 1.00 60.75  ? 528 TRP A CB  1 
ATOM   2507 C CG  . TRP A 1 528 ? 225.677 169.147 203.580 1.00 64.13  ? 528 TRP A CG  1 
ATOM   2508 C CD1 . TRP A 1 528 ? 224.905 169.971 204.368 1.00 71.54  ? 528 TRP A CD1 1 
ATOM   2509 C CD2 . TRP A 1 528 ? 227.026 169.325 204.042 1.00 65.33  ? 528 TRP A CD2 1 
ATOM   2510 N NE1 . TRP A 1 528 ? 225.701 170.697 205.222 1.00 73.07  ? 528 TRP A NE1 1 
ATOM   2511 C CE2 . TRP A 1 528 ? 227.002 170.308 205.052 1.00 66.82  ? 528 TRP A CE2 1 
ATOM   2512 C CE3 . TRP A 1 528 ? 228.250 168.765 203.679 1.00 68.79  ? 528 TRP A CE3 1 
ATOM   2513 C CZ2 . TRP A 1 528 ? 228.154 170.745 205.688 1.00 66.16  ? 528 TRP A CZ2 1 
ATOM   2514 C CZ3 . TRP A 1 528 ? 229.381 169.188 204.309 1.00 68.90  ? 528 TRP A CZ3 1 
ATOM   2515 C CH2 . TRP A 1 528 ? 229.332 170.169 205.310 1.00 66.76  ? 528 TRP A CH2 1 
ATOM   2516 N N   . ASP A 1 529 ? 222.060 168.646 202.334 1.00 56.34  ? 529 ASP A N   1 
ATOM   2517 C CA  . ASP A 1 529 ? 220.866 169.429 202.633 1.00 48.66  ? 529 ASP A CA  1 
ATOM   2518 C C   . ASP A 1 529 ? 219.879 168.630 203.474 1.00 56.22  ? 529 ASP A C   1 
ATOM   2519 O O   . ASP A 1 529 ? 219.237 169.178 204.377 1.00 58.29  ? 529 ASP A O   1 
ATOM   2520 C CB  . ASP A 1 529 ? 220.209 169.901 201.337 1.00 48.65  ? 529 ASP A CB  1 
ATOM   2521 C CG  . ASP A 1 529 ? 220.996 170.996 200.654 1.00 50.74  ? 529 ASP A CG  1 
ATOM   2522 O OD1 . ASP A 1 529 ? 222.057 171.382 201.184 1.00 50.59  ? 529 ASP A OD1 1 
ATOM   2523 O OD2 . ASP A 1 529 ? 220.554 171.473 199.588 1.00 45.86  ? 529 ASP A OD2 1 
ATOM   2524 N N   . LEU A 1 530 ? 219.746 167.332 203.199 1.00 55.47  ? 530 LEU A N   1 
ATOM   2525 C CA  . LEU A 1 530 ? 218.800 166.517 203.947 1.00 53.61  ? 530 LEU A CA  1 
ATOM   2526 C C   . LEU A 1 530 ? 219.296 166.138 205.338 1.00 59.24  ? 530 LEU A C   1 
ATOM   2527 O O   . LEU A 1 530 ? 218.472 165.858 206.216 1.00 61.32  ? 530 LEU A O   1 
ATOM   2528 C CB  . LEU A 1 530 ? 218.473 165.246 203.165 1.00 59.57  ? 530 LEU A CB  1 
ATOM   2529 C CG  . LEU A 1 530 ? 217.315 165.398 202.181 1.00 63.59  ? 530 LEU A CG  1 
ATOM   2530 C CD1 . LEU A 1 530 ? 216.838 164.036 201.696 1.00 71.08  ? 530 LEU A CD1 1 
ATOM   2531 C CD2 . LEU A 1 530 ? 216.182 166.215 202.786 1.00 57.56  ? 530 LEU A CD2 1 
ATOM   2532 N N   . LYS A 1 531 ? 220.608 166.123 205.564 1.00 70.25  ? 531 LYS A N   1 
ATOM   2533 C CA  . LYS A 1 531 ? 221.173 165.593 206.800 1.00 73.09  ? 531 LYS A CA  1 
ATOM   2534 C C   . LYS A 1 531 ? 221.682 166.662 207.755 1.00 74.07  ? 531 LYS A C   1 
ATOM   2535 O O   . LYS A 1 531 ? 221.333 166.641 208.938 1.00 68.73  ? 531 LYS A O   1 
ATOM   2536 C CB  . LYS A 1 531 ? 222.311 164.617 206.468 1.00 70.18  ? 531 LYS A CB  1 
ATOM   2537 C CG  . LYS A 1 531 ? 222.903 163.903 207.674 1.00 71.42  ? 531 LYS A CG  1 
ATOM   2538 C CD  . LYS A 1 531 ? 221.842 163.338 208.608 1.00 70.40  ? 531 LYS A CD  1 
ATOM   2539 C CE  . LYS A 1 531 ? 221.335 161.992 208.120 1.00 73.55  ? 531 LYS A CE  1 
ATOM   2540 N NZ  . LYS A 1 531 ? 220.842 161.148 209.245 1.00 75.87  ? 531 LYS A NZ  1 
ATOM   2541 N N   . MET A 1 532 ? 222.518 167.589 207.291 1.00 74.23  ? 532 MET A N   1 
ATOM   2542 C CA  . MET A 1 532 ? 223.120 168.538 208.218 1.00 71.43  ? 532 MET A CA  1 
ATOM   2543 C C   . MET A 1 532 ? 222.435 169.900 208.199 1.00 76.06  ? 532 MET A C   1 
ATOM   2544 O O   . MET A 1 532 ? 222.264 170.517 209.256 1.00 75.30  ? 532 MET A O   1 
ATOM   2545 C CB  . MET A 1 532 ? 224.610 168.700 207.914 1.00 69.60  ? 532 MET A CB  1 
ATOM   2546 C CG  . MET A 1 532 ? 225.490 167.699 208.644 1.00 79.82  ? 532 MET A CG  1 
ATOM   2547 S SD  . MET A 1 532 ? 226.245 168.410 210.114 1.00 93.24  ? 532 MET A SD  1 
ATOM   2548 C CE  . MET A 1 532 ? 227.224 169.706 209.379 1.00 74.41  ? 532 MET A CE  1 
ATOM   2549 N N   . ASP A 1 533 ? 222.028 170.383 207.024 1.00 62.38  ? 533 ASP A N   1 
ATOM   2550 C CA  . ASP A 1 533 ? 221.357 171.677 206.948 1.00 50.96  ? 533 ASP A CA  1 
ATOM   2551 C C   . ASP A 1 533 ? 219.964 171.607 207.561 1.00 55.36  ? 533 ASP A C   1 
ATOM   2552 O O   . ASP A 1 533 ? 219.643 172.353 208.492 1.00 60.70  ? 533 ASP A O   1 
ATOM   2553 C CB  . ASP A 1 533 ? 221.287 172.152 205.494 1.00 50.90  ? 533 ASP A CB  1 
ATOM   2554 C CG  . ASP A 1 533 ? 222.521 172.925 205.073 1.00 55.87  ? 533 ASP A CG  1 
ATOM   2555 O OD1 . ASP A 1 533 ? 223.343 173.253 205.953 1.00 53.01  ? 533 ASP A OD1 1 
ATOM   2556 O OD2 . ASP A 1 533 ? 222.669 173.206 203.865 1.00 58.49  ? 533 ASP A OD2 1 
ATOM   2557 N N   . TRP A 1 534 ? 219.119 170.712 207.047 1.00 48.54  ? 534 TRP A N   1 
ATOM   2558 C CA  . TRP A 1 534 ? 217.789 170.541 207.621 1.00 48.38  ? 534 TRP A CA  1 
ATOM   2559 C C   . TRP A 1 534 ? 217.835 169.752 208.922 1.00 48.66  ? 534 TRP A C   1 
ATOM   2560 O O   . TRP A 1 534 ? 216.984 169.952 209.796 1.00 49.91  ? 534 TRP A O   1 
ATOM   2561 C CB  . TRP A 1 534 ? 216.862 169.860 206.614 1.00 47.94  ? 534 TRP A CB  1 
ATOM   2562 C CG  . TRP A 1 534 ? 216.651 170.644 205.350 1.00 47.65  ? 534 TRP A CG  1 
ATOM   2563 C CD1 . TRP A 1 534 ? 217.351 171.740 204.934 1.00 50.17  ? 534 TRP A CD1 1 
ATOM   2564 C CD2 . TRP A 1 534 ? 215.674 170.386 204.336 1.00 46.54  ? 534 TRP A CD2 1 
ATOM   2565 N NE1 . TRP A 1 534 ? 216.869 172.180 203.727 1.00 45.17  ? 534 TRP A NE1 1 
ATOM   2566 C CE2 . TRP A 1 534 ? 215.840 171.366 203.337 1.00 45.55  ? 534 TRP A CE2 1 
ATOM   2567 C CE3 . TRP A 1 534 ? 214.675 169.423 204.175 1.00 47.76  ? 534 TRP A CE3 1 
ATOM   2568 C CZ2 . TRP A 1 534 ? 215.044 171.410 202.197 1.00 45.79  ? 534 TRP A CZ2 1 
ATOM   2569 C CZ3 . TRP A 1 534 ? 213.887 169.468 203.041 1.00 55.03  ? 534 TRP A CZ3 1 
ATOM   2570 C CH2 . TRP A 1 534 ? 214.075 170.455 202.067 1.00 52.96  ? 534 TRP A CH2 1 
ATOM   2571 N N   . GLY A 1 535 ? 218.809 168.857 209.069 1.00 60.52  ? 535 GLY A N   1 
ATOM   2572 C CA  . GLY A 1 535 ? 218.911 168.050 210.267 1.00 65.52  ? 535 GLY A CA  1 
ATOM   2573 C C   . GLY A 1 535 ? 218.008 166.840 210.301 1.00 69.96  ? 535 GLY A C   1 
ATOM   2574 O O   . GLY A 1 535 ? 217.883 166.205 211.351 1.00 74.33  ? 535 GLY A O   1 
ATOM   2575 N N   . LEU A 1 536 ? 217.386 166.490 209.179 1.00 77.66  ? 536 LEU A N   1 
ATOM   2576 C CA  . LEU A 1 536 ? 216.428 165.397 209.142 1.00 79.80  ? 536 LEU A CA  1 
ATOM   2577 C C   . LEU A 1 536 ? 217.143 164.050 209.249 1.00 84.96  ? 536 LEU A C   1 
ATOM   2578 O O   . LEU A 1 536 ? 218.368 163.970 209.376 1.00 86.03  ? 536 LEU A O   1 
ATOM   2579 C CB  . LEU A 1 536 ? 215.589 165.476 207.869 1.00 82.67  ? 536 LEU A CB  1 
ATOM   2580 C CG  . LEU A 1 536 ? 214.819 166.783 207.674 1.00 79.21  ? 536 LEU A CG  1 
ATOM   2581 C CD1 . LEU A 1 536 ? 213.918 166.697 206.456 1.00 76.72  ? 536 LEU A CD1 1 
ATOM   2582 C CD2 . LEU A 1 536 ? 214.014 167.120 208.917 1.00 80.06  ? 536 LEU A CD2 1 
ATOM   2583 N N   . PHE A 1 537 ? 216.352 162.974 209.195 1.00 92.36  ? 537 PHE A N   1 
ATOM   2584 C CA  . PHE A 1 537 ? 216.854 161.605 209.343 1.00 91.66  ? 537 PHE A CA  1 
ATOM   2585 C C   . PHE A 1 537 ? 217.607 161.435 210.661 1.00 93.27  ? 537 PHE A C   1 
ATOM   2586 O O   . PHE A 1 537 ? 218.625 160.745 210.733 1.00 93.06  ? 537 PHE A O   1 
ATOM   2587 C CB  . PHE A 1 537 ? 217.734 161.188 208.159 1.00 87.29  ? 537 PHE A CB  1 
ATOM   2588 C CG  . PHE A 1 537 ? 217.060 161.293 206.813 1.00 88.08  ? 537 PHE A CG  1 
ATOM   2589 C CD1 . PHE A 1 537 ? 215.694 161.494 206.706 1.00 92.98  ? 537 PHE A CD1 1 
ATOM   2590 C CD2 . PHE A 1 537 ? 217.799 161.145 205.651 1.00 91.58  ? 537 PHE A CD2 1 
ATOM   2591 C CE1 . PHE A 1 537 ? 215.085 161.579 205.469 1.00 93.61  ? 537 PHE A CE1 1 
ATOM   2592 C CE2 . PHE A 1 537 ? 217.195 161.229 204.410 1.00 94.62  ? 537 PHE A CE2 1 
ATOM   2593 C CZ  . PHE A 1 537 ? 215.837 161.445 204.319 1.00 91.46  ? 537 PHE A CZ  1 
ATOM   2594 N N   . ASP A 1 538 ? 217.102 162.076 211.712 1.00 102.05 ? 538 ASP A N   1 
ATOM   2595 C CA  . ASP A 1 538 ? 217.742 161.990 213.017 1.00 101.57 ? 538 ASP A CA  1 
ATOM   2596 C C   . ASP A 1 538 ? 217.453 160.643 213.666 1.00 102.79 ? 538 ASP A C   1 
ATOM   2597 O O   . ASP A 1 538 ? 216.329 160.136 213.611 1.00 101.55 ? 538 ASP A O   1 
ATOM   2598 C CB  . ASP A 1 538 ? 217.261 163.126 213.919 1.00 102.62 ? 538 ASP A CB  1 
ATOM   2599 C CG  . ASP A 1 538 ? 217.678 162.939 215.363 1.00 107.13 ? 538 ASP A CG  1 
ATOM   2600 O OD1 . ASP A 1 538 ? 218.878 162.696 215.609 1.00 108.72 ? 538 ASP A OD1 1 
ATOM   2601 O OD2 . ASP A 1 538 ? 216.807 163.037 216.253 1.00 107.88 ? 538 ASP A OD2 1 
ATOM   2602 N N   . LYS A 1 539 ? 218.484 160.057 214.278 1.00 109.47 ? 539 LYS A N   1 
ATOM   2603 C CA  . LYS A 1 539 ? 218.316 158.769 214.944 1.00 110.00 ? 539 LYS A CA  1 
ATOM   2604 C C   . LYS A 1 539 ? 217.424 158.892 216.173 1.00 110.03 ? 539 LYS A C   1 
ATOM   2605 O O   . LYS A 1 539 ? 216.634 157.988 216.467 1.00 110.09 ? 539 LYS A O   1 
ATOM   2606 C CB  . LYS A 1 539 ? 219.680 158.192 215.321 1.00 107.98 ? 539 LYS A CB  1 
ATOM   2607 C CG  . LYS A 1 539 ? 220.329 157.311 214.252 1.00 109.71 ? 539 LYS A CG  1 
ATOM   2608 C CD  . LYS A 1 539 ? 219.314 156.462 213.491 1.00 110.16 ? 539 LYS A CD  1 
ATOM   2609 C CE  . LYS A 1 539 ? 219.116 156.958 212.062 1.00 107.42 ? 539 LYS A CE  1 
ATOM   2610 N NZ  . LYS A 1 539 ? 218.279 156.024 211.260 1.00 105.55 ? 539 LYS A NZ  1 
ATOM   2611 N N   . ASN A 1 540 ? 217.535 160.002 216.904 1.00 106.16 ? 540 ASN A N   1 
ATOM   2612 C CA  . ASN A 1 540 ? 216.748 160.237 218.107 1.00 105.08 ? 540 ASN A CA  1 
ATOM   2613 C C   . ASN A 1 540 ? 215.350 160.771 217.810 1.00 106.68 ? 540 ASN A C   1 
ATOM   2614 O O   . ASN A 1 540 ? 214.705 161.315 218.715 1.00 107.63 ? 540 ASN A O   1 
ATOM   2615 C CB  . ASN A 1 540 ? 217.487 161.206 219.035 1.00 104.08 ? 540 ASN A CB  1 
ATOM   2616 C CG  . ASN A 1 540 ? 218.960 160.878 219.166 1.00 105.61 ? 540 ASN A CG  1 
ATOM   2617 O OD1 . ASN A 1 540 ? 219.378 159.743 218.940 1.00 108.45 ? 540 ASN A OD1 1 
ATOM   2618 N ND2 . ASN A 1 540 ? 219.758 161.875 219.531 1.00 105.62 ? 540 ASN A ND2 1 
ATOM   2619 N N   . ALA A 1 541 ? 214.877 160.634 216.569 1.00 100.98 ? 541 ALA A N   1 
ATOM   2620 C CA  . ALA A 1 541 ? 213.578 161.188 216.200 1.00 101.04 ? 541 ALA A CA  1 
ATOM   2621 C C   . ALA A 1 541 ? 212.444 160.527 216.972 1.00 102.48 ? 541 ALA A C   1 
ATOM   2622 O O   . ALA A 1 541 ? 211.544 161.211 217.474 1.00 101.44 ? 541 ALA A O   1 
ATOM   2623 C CB  . ALA A 1 541 ? 213.356 161.036 214.697 1.00 101.12 ? 541 ALA A CB  1 
ATOM   2624 N N   . GLY A 1 542 ? 212.467 159.202 217.080 1.00 114.24 ? 542 GLY A N   1 
ATOM   2625 C CA  . GLY A 1 542 ? 211.397 158.489 217.746 1.00 113.67 ? 542 GLY A CA  1 
ATOM   2626 C C   . GLY A 1 542 ? 210.138 158.393 216.908 1.00 115.97 ? 542 GLY A C   1 
ATOM   2627 O O   . GLY A 1 542 ? 210.110 157.684 215.898 1.00 116.55 ? 542 GLY A O   1 
ATOM   2628 N N   . GLU A 1 543 ? 209.085 159.101 217.324 1.00 120.89 ? 543 GLU A N   1 
ATOM   2629 C CA  . GLU A 1 543 ? 207.820 159.047 216.597 1.00 120.52 ? 543 GLU A CA  1 
ATOM   2630 C C   . GLU A 1 543 ? 207.951 159.636 215.197 1.00 121.57 ? 543 GLU A C   1 
ATOM   2631 O O   . GLU A 1 543 ? 207.422 159.074 214.230 1.00 119.85 ? 543 GLU A O   1 
ATOM   2632 C CB  . GLU A 1 543 ? 206.730 159.774 217.386 1.00 119.30 ? 543 GLU A CB  1 
ATOM   2633 C CG  . GLU A 1 543 ? 205.546 160.235 216.545 1.00 120.57 ? 543 GLU A CG  1 
ATOM   2634 C CD  . GLU A 1 543 ? 204.709 159.083 216.018 1.00 121.65 ? 543 GLU A CD  1 
ATOM   2635 O OE1 . GLU A 1 543 ? 204.820 157.963 216.560 1.00 121.35 ? 543 GLU A OE1 1 
ATOM   2636 O OE2 . GLU A 1 543 ? 203.940 159.299 215.058 1.00 121.14 ? 543 GLU A OE2 1 
ATOM   2637 N N   . ASN A 1 544 ? 208.650 160.765 215.067 1.00 110.89 ? 544 ASN A N   1 
ATOM   2638 C CA  . ASN A 1 544 ? 208.801 161.427 213.777 1.00 107.92 ? 544 ASN A CA  1 
ATOM   2639 C C   . ASN A 1 544 ? 209.564 160.546 212.796 1.00 105.13 ? 544 ASN A C   1 
ATOM   2640 O O   . ASN A 1 544 ? 210.751 160.267 212.994 1.00 101.02 ? 544 ASN A O   1 
ATOM   2641 C CB  . ASN A 1 544 ? 209.509 162.773 213.944 1.00 105.20 ? 544 ASN A CB  1 
ATOM   2642 C CG  . ASN A 1 544 ? 208.777 163.702 214.890 1.00 104.10 ? 544 ASN A CG  1 
ATOM   2643 O OD1 . ASN A 1 544 ? 209.354 164.206 215.853 1.00 103.23 ? 544 ASN A OD1 1 
ATOM   2644 N ND2 . ASN A 1 544 ? 207.497 163.933 214.621 1.00 103.45 ? 544 ASN A ND2 1 
ATOM   2645 N N   . THR A 1 545 ? 208.891 160.104 211.738 1.00 104.00 ? 545 THR A N   1 
ATOM   2646 C CA  . THR A 1 545 ? 209.498 159.207 210.764 1.00 105.29 ? 545 THR A CA  1 
ATOM   2647 C C   . THR A 1 545 ? 210.439 159.990 209.856 1.00 105.38 ? 545 THR A C   1 
ATOM   2648 O O   . THR A 1 545 ? 210.009 160.910 209.153 1.00 105.85 ? 545 THR A O   1 
ATOM   2649 C CB  . THR A 1 545 ? 208.419 158.505 209.942 1.00 104.95 ? 545 THR A CB  1 
ATOM   2650 O OG1 . THR A 1 545 ? 207.772 159.456 209.088 1.00 102.97 ? 545 THR A OG1 1 
ATOM   2651 C CG2 . THR A 1 545 ? 207.384 157.869 210.859 1.00 104.83 ? 545 THR A CG2 1 
ATOM   2652 N N   . PHE A 1 546 ? 211.723 159.621 209.877 1.00 104.27 ? 546 PHE A N   1 
ATOM   2653 C CA  . PHE A 1 546 ? 212.744 160.210 209.005 1.00 102.60 ? 546 PHE A CA  1 
ATOM   2654 C C   . PHE A 1 546 ? 212.844 161.724 209.178 1.00 104.80 ? 546 PHE A C   1 
ATOM   2655 O O   . PHE A 1 546 ? 213.144 162.448 208.226 1.00 107.84 ? 546 PHE A O   1 
ATOM   2656 C CB  . PHE A 1 546 ? 212.492 159.854 207.535 1.00 104.27 ? 546 PHE A CB  1 
ATOM   2657 C CG  . PHE A 1 546 ? 211.805 158.530 207.339 1.00 104.32 ? 546 PHE A CG  1 
ATOM   2658 C CD1 . PHE A 1 546 ? 212.450 157.346 207.658 1.00 105.55 ? 546 PHE A CD1 1 
ATOM   2659 C CD2 . PHE A 1 546 ? 210.515 158.471 206.840 1.00 104.29 ? 546 PHE A CD2 1 
ATOM   2660 C CE1 . PHE A 1 546 ? 211.821 156.128 207.480 1.00 106.04 ? 546 PHE A CE1 1 
ATOM   2661 C CE2 . PHE A 1 546 ? 209.880 157.256 206.661 1.00 105.45 ? 546 PHE A CE2 1 
ATOM   2662 C CZ  . PHE A 1 546 ? 210.534 156.084 206.981 1.00 106.65 ? 546 PHE A CZ  1 
ATOM   2663 N N   . LEU A 1 547 ? 212.598 162.214 210.392 1.00 95.49  ? 547 LEU A N   1 
ATOM   2664 C CA  . LEU A 1 547 ? 212.648 163.646 210.664 1.00 93.61  ? 547 LEU A CA  1 
ATOM   2665 C C   . LEU A 1 547 ? 213.465 163.935 211.916 1.00 92.63  ? 547 LEU A C   1 
ATOM   2666 O O   . LEU A 1 547 ? 214.162 163.053 212.427 1.00 95.26  ? 547 LEU A O   1 
ATOM   2667 C CB  . LEU A 1 547 ? 211.236 164.216 210.810 1.00 95.61  ? 547 LEU A CB  1 
ATOM   2668 C CG  . LEU A 1 547 ? 210.360 164.187 209.557 1.00 92.37  ? 547 LEU A CG  1 
ATOM   2669 C CD1 . LEU A 1 547 ? 208.984 164.765 209.847 1.00 91.49  ? 547 LEU A CD1 1 
ATOM   2670 C CD2 . LEU A 1 547 ? 211.032 164.934 208.417 1.00 88.43  ? 547 LEU A CD2 1 
ATOM   2671 N N   . ARG A 1 548 ? 213.407 165.171 212.401 1.00 81.51  ? 548 ARG A N   1 
ATOM   2672 C CA  . ARG A 1 548 ? 214.051 165.524 213.655 1.00 81.28  ? 548 ARG A CA  1 
ATOM   2673 C C   . ARG A 1 548 ? 213.198 165.074 214.838 1.00 80.73  ? 548 ARG A C   1 
ATOM   2674 O O   . ARG A 1 548 ? 212.018 164.743 214.700 1.00 79.54  ? 548 ARG A O   1 
ATOM   2675 C CB  . ARG A 1 548 ? 214.296 167.030 213.734 1.00 83.18  ? 548 ARG A CB  1 
ATOM   2676 C CG  . ARG A 1 548 ? 215.632 167.474 213.169 1.00 80.93  ? 548 ARG A CG  1 
ATOM   2677 C CD  . ARG A 1 548 ? 215.927 168.924 213.528 1.00 80.70  ? 548 ARG A CD  1 
ATOM   2678 N NE  . ARG A 1 548 ? 214.816 169.814 213.206 1.00 79.22  ? 548 ARG A NE  1 
ATOM   2679 C CZ  . ARG A 1 548 ? 214.390 170.081 211.978 1.00 75.74  ? 548 ARG A CZ  1 
ATOM   2680 N NH1 . ARG A 1 548 ? 214.991 169.580 210.911 1.00 77.38  ? 548 ARG A NH1 1 
ATOM   2681 N NH2 . ARG A 1 548 ? 213.340 170.879 211.816 1.00 74.97  ? 548 ARG A NH2 1 
ATOM   2682 N N   . GLU A 1 549 ? 213.822 165.059 216.019 1.00 86.49  ? 549 GLU A N   1 
ATOM   2683 C CA  . GLU A 1 549 ? 213.101 164.676 217.229 1.00 87.27  ? 549 GLU A CA  1 
ATOM   2684 C C   . GLU A 1 549 ? 212.004 165.681 217.561 1.00 87.57  ? 549 GLU A C   1 
ATOM   2685 O O   . GLU A 1 549 ? 210.899 165.294 217.959 1.00 86.32  ? 549 GLU A O   1 
ATOM   2686 C CB  . GLU A 1 549 ? 214.075 164.530 218.398 1.00 86.67  ? 549 GLU A CB  1 
ATOM   2687 C CG  . GLU A 1 549 ? 213.408 164.291 219.746 1.00 88.09  ? 549 GLU A CG  1 
ATOM   2688 C CD  . GLU A 1 549 ? 213.306 165.549 220.586 1.00 88.05  ? 549 GLU A CD  1 
ATOM   2689 O OE1 . GLU A 1 549 ? 214.341 166.220 220.783 1.00 90.23  ? 549 GLU A OE1 1 
ATOM   2690 O OE2 . GLU A 1 549 ? 212.191 165.866 221.050 1.00 87.64  ? 549 GLU A OE2 1 
ATOM   2691 N N   . GLU A 1 550 ? 212.287 166.971 217.403 1.00 84.31  ? 550 GLU A N   1 
ATOM   2692 C CA  . GLU A 1 550 ? 211.326 168.031 217.672 1.00 80.82  ? 550 GLU A CA  1 
ATOM   2693 C C   . GLU A 1 550 ? 211.154 168.877 216.419 1.00 82.54  ? 550 GLU A C   1 
ATOM   2694 O O   . GLU A 1 550 ? 212.126 169.136 215.701 1.00 82.66  ? 550 GLU A O   1 
ATOM   2695 C CB  . GLU A 1 550 ? 211.772 168.897 218.860 1.00 78.54  ? 550 GLU A CB  1 
ATOM   2696 C CG  . GLU A 1 550 ? 212.986 169.791 218.611 1.00 80.49  ? 550 GLU A CG  1 
ATOM   2697 C CD  . GLU A 1 550 ? 214.309 169.038 218.580 1.00 82.49  ? 550 GLU A CD  1 
ATOM   2698 O OE1 . GLU A 1 550 ? 214.305 167.799 218.427 1.00 84.76  ? 550 GLU A OE1 1 
ATOM   2699 O OE2 . GLU A 1 550 ? 215.363 169.695 218.710 1.00 83.15  ? 550 GLU A OE2 1 
ATOM   2700 N N   . ILE A 1 551 ? 209.918 169.288 216.149 1.00 76.48  ? 551 ILE A N   1 
ATOM   2701 C CA  . ILE A 1 551 ? 209.583 170.057 214.957 1.00 74.99  ? 551 ILE A CA  1 
ATOM   2702 C C   . ILE A 1 551 ? 208.783 171.284 215.373 1.00 74.97  ? 551 ILE A C   1 
ATOM   2703 O O   . ILE A 1 551 ? 207.933 171.211 216.266 1.00 74.60  ? 551 ILE A O   1 
ATOM   2704 C CB  . ILE A 1 551 ? 208.794 169.210 213.936 1.00 73.56  ? 551 ILE A CB  1 
ATOM   2705 C CG1 . ILE A 1 551 ? 207.647 168.472 214.626 1.00 78.51  ? 551 ILE A CG1 1 
ATOM   2706 C CG2 . ILE A 1 551 ? 209.717 168.225 213.239 1.00 69.25  ? 551 ILE A CG2 1 
ATOM   2707 C CD1 . ILE A 1 551 ? 206.746 167.720 213.674 1.00 74.74  ? 551 ILE A CD1 1 
ATOM   2708 N N   . VAL A 1 552 ? 209.064 172.412 214.726 1.00 65.97  ? 552 VAL A N   1 
ATOM   2709 C CA  . VAL A 1 552 ? 208.370 173.660 215.032 1.00 62.30  ? 552 VAL A CA  1 
ATOM   2710 C C   . VAL A 1 552 ? 207.197 173.892 214.087 1.00 64.89  ? 552 VAL A C   1 
ATOM   2711 O O   . VAL A 1 552 ? 206.134 174.352 214.511 1.00 68.59  ? 552 VAL A O   1 
ATOM   2712 C CB  . VAL A 1 552 ? 209.371 174.833 214.995 1.00 59.14  ? 552 VAL A CB  1 
ATOM   2713 C CG1 . VAL A 1 552 ? 208.650 176.157 214.803 1.00 59.05  ? 552 VAL A CG1 1 
ATOM   2714 C CG2 . VAL A 1 552 ? 210.196 174.858 216.269 1.00 61.54  ? 552 VAL A CG2 1 
ATOM   2715 N N   . TYR A 1 553 ? 207.366 173.564 212.809 1.00 65.41  ? 553 TYR A N   1 
ATOM   2716 C CA  . TYR A 1 553 ? 206.336 173.841 211.822 1.00 65.68  ? 553 TYR A CA  1 
ATOM   2717 C C   . TYR A 1 553 ? 205.090 172.999 212.105 1.00 67.42  ? 553 TYR A C   1 
ATOM   2718 O O   . TYR A 1 553 ? 205.189 171.885 212.625 1.00 69.61  ? 553 TYR A O   1 
ATOM   2719 C CB  . TYR A 1 553 ? 206.866 173.565 210.417 1.00 60.13  ? 553 TYR A CB  1 
ATOM   2720 C CG  . TYR A 1 553 ? 207.923 174.554 209.971 1.00 60.50  ? 553 TYR A CG  1 
ATOM   2721 C CD1 . TYR A 1 553 ? 208.195 175.693 210.719 1.00 59.35  ? 553 TYR A CD1 1 
ATOM   2722 C CD2 . TYR A 1 553 ? 208.660 174.341 208.816 1.00 67.25  ? 553 TYR A CD2 1 
ATOM   2723 C CE1 . TYR A 1 553 ? 209.161 176.595 210.325 1.00 55.28  ? 553 TYR A CE1 1 
ATOM   2724 C CE2 . TYR A 1 553 ? 209.631 175.240 208.413 1.00 68.86  ? 553 TYR A CE2 1 
ATOM   2725 C CZ  . TYR A 1 553 ? 209.876 176.365 209.173 1.00 55.70  ? 553 TYR A CZ  1 
ATOM   2726 O OH  . TYR A 1 553 ? 210.840 177.266 208.783 1.00 52.67  ? 553 TYR A OH  1 
ATOM   2727 N N   . PRO A 1 554 ? 203.902 173.521 211.782 1.00 81.15  ? 554 PRO A N   1 
ATOM   2728 C CA  . PRO A 1 554 ? 202.663 172.885 212.265 1.00 82.38  ? 554 PRO A CA  1 
ATOM   2729 C C   . PRO A 1 554 ? 202.459 171.452 211.803 1.00 81.54  ? 554 PRO A C   1 
ATOM   2730 O O   . PRO A 1 554 ? 201.897 170.650 212.560 1.00 80.71  ? 554 PRO A O   1 
ATOM   2731 C CB  . PRO A 1 554 ? 201.562 173.809 211.722 1.00 79.56  ? 554 PRO A CB  1 
ATOM   2732 C CG  . PRO A 1 554 ? 202.200 174.560 210.600 1.00 78.54  ? 554 PRO A CG  1 
ATOM   2733 C CD  . PRO A 1 554 ? 203.628 174.738 211.000 1.00 79.14  ? 554 PRO A CD  1 
ATOM   2734 N N   . GLN A 1 555 ? 202.889 171.095 210.596 1.00 84.94  ? 555 GLN A N   1 
ATOM   2735 C CA  . GLN A 1 555 ? 202.585 169.785 210.036 1.00 88.71  ? 555 GLN A CA  1 
ATOM   2736 C C   . GLN A 1 555 ? 203.855 169.100 209.555 1.00 88.53  ? 555 GLN A C   1 
ATOM   2737 O O   . GLN A 1 555 ? 204.732 169.737 208.963 1.00 89.81  ? 555 GLN A O   1 
ATOM   2738 C CB  . GLN A 1 555 ? 201.584 169.899 208.879 1.00 90.49  ? 555 GLN A CB  1 
ATOM   2739 C CG  . GLN A 1 555 ? 200.978 168.572 208.451 1.00 92.17  ? 555 GLN A CG  1 
ATOM   2740 C CD  . GLN A 1 555 ? 200.043 167.992 209.496 1.00 92.24  ? 555 GLN A CD  1 
ATOM   2741 O OE1 . GLN A 1 555 ? 199.511 168.713 210.340 1.00 86.89  ? 555 GLN A OE1 1 
ATOM   2742 N NE2 . GLN A 1 555 ? 199.840 166.681 209.444 1.00 91.99  ? 555 GLN A NE2 1 
ATOM   2743 N N   . LYS A 1 556 ? 203.945 167.792 209.817 1.00 85.86  ? 556 LYS A N   1 
ATOM   2744 C CA  . LYS A 1 556 ? 205.072 167.008 209.322 1.00 84.19  ? 556 LYS A CA  1 
ATOM   2745 C C   . LYS A 1 556 ? 204.949 166.730 207.829 1.00 84.52  ? 556 LYS A C   1 
ATOM   2746 O O   . LYS A 1 556 ? 205.955 166.441 207.168 1.00 84.76  ? 556 LYS A O   1 
ATOM   2747 C CB  . LYS A 1 556 ? 205.181 165.697 210.099 1.00 85.91  ? 556 LYS A CB  1 
ATOM   2748 C CG  . LYS A 1 556 ? 204.540 165.736 211.476 1.00 87.02  ? 556 LYS A CG  1 
ATOM   2749 C CD  . LYS A 1 556 ? 205.016 164.581 212.340 1.00 85.85  ? 556 LYS A CD  1 
ATOM   2750 C CE  . LYS A 1 556 ? 204.494 163.252 211.821 1.00 87.12  ? 556 LYS A CE  1 
ATOM   2751 N NZ  . LYS A 1 556 ? 204.879 162.119 212.707 1.00 84.37  ? 556 LYS A NZ  1 
ATOM   2752 N N   . ALA A 1 557 ? 203.730 166.796 207.287 1.00 83.35  ? 557 ALA A N   1 
ATOM   2753 C CA  . ALA A 1 557 ? 203.554 166.663 205.845 1.00 83.52  ? 557 ALA A CA  1 
ATOM   2754 C C   . ALA A 1 557 ? 204.314 167.753 205.105 1.00 82.87  ? 557 ALA A C   1 
ATOM   2755 O O   . ALA A 1 557 ? 204.810 167.534 203.994 1.00 77.90  ? 557 ALA A O   1 
ATOM   2756 C CB  . ALA A 1 557 ? 202.068 166.703 205.487 1.00 79.88  ? 557 ALA A CB  1 
ATOM   2757 N N   . TYR A 1 558 ? 204.418 168.937 205.712 1.00 82.05  ? 558 TYR A N   1 
ATOM   2758 C CA  . TYR A 1 558 ? 205.263 169.987 205.156 1.00 78.94  ? 558 TYR A CA  1 
ATOM   2759 C C   . TYR A 1 558 ? 206.709 169.520 205.065 1.00 75.97  ? 558 TYR A C   1 
ATOM   2760 O O   . TYR A 1 558 ? 207.377 169.717 204.044 1.00 77.88  ? 558 TYR A O   1 
ATOM   2761 C CB  . TYR A 1 558 ? 205.158 171.249 206.013 1.00 80.22  ? 558 TYR A CB  1 
ATOM   2762 C CG  . TYR A 1 558 ? 203.923 172.079 205.748 1.00 81.50  ? 558 TYR A CG  1 
ATOM   2763 C CD1 . TYR A 1 558 ? 203.042 171.744 204.729 1.00 78.71  ? 558 TYR A CD1 1 
ATOM   2764 C CD2 . TYR A 1 558 ? 203.634 173.192 206.525 1.00 79.24  ? 558 TYR A CD2 1 
ATOM   2765 C CE1 . TYR A 1 558 ? 201.911 172.500 204.487 1.00 77.58  ? 558 TYR A CE1 1 
ATOM   2766 C CE2 . TYR A 1 558 ? 202.506 173.952 206.292 1.00 76.73  ? 558 TYR A CE2 1 
ATOM   2767 C CZ  . TYR A 1 558 ? 201.648 173.603 205.272 1.00 79.41  ? 558 TYR A CZ  1 
ATOM   2768 O OH  . TYR A 1 558 ? 200.523 174.359 205.036 1.00 83.55  ? 558 TYR A OH  1 
ATOM   2769 N N   . TYR A 1 559 ? 207.204 168.875 206.124 1.00 69.44  ? 559 TYR A N   1 
ATOM   2770 C CA  . TYR A 1 559 ? 208.566 168.353 206.106 1.00 71.46  ? 559 TYR A CA  1 
ATOM   2771 C C   . TYR A 1 559 ? 208.740 167.322 205.000 1.00 78.75  ? 559 TYR A C   1 
ATOM   2772 O O   . TYR A 1 559 ? 209.720 167.361 204.247 1.00 75.53  ? 559 TYR A O   1 
ATOM   2773 C CB  . TYR A 1 559 ? 208.913 167.738 207.462 1.00 71.19  ? 559 TYR A CB  1 
ATOM   2774 C CG  . TYR A 1 559 ? 209.087 168.736 208.583 1.00 71.82  ? 559 TYR A CG  1 
ATOM   2775 C CD1 . TYR A 1 559 ? 207.994 169.400 209.120 1.00 74.24  ? 559 TYR A CD1 1 
ATOM   2776 C CD2 . TYR A 1 559 ? 210.343 169.006 209.110 1.00 72.30  ? 559 TYR A CD2 1 
ATOM   2777 C CE1 . TYR A 1 559 ? 208.146 170.308 210.145 1.00 75.07  ? 559 TYR A CE1 1 
ATOM   2778 C CE2 . TYR A 1 559 ? 210.504 169.916 210.136 1.00 72.58  ? 559 TYR A CE2 1 
ATOM   2779 C CZ  . TYR A 1 559 ? 209.401 170.563 210.648 1.00 73.43  ? 559 TYR A CZ  1 
ATOM   2780 O OH  . TYR A 1 559 ? 209.548 171.469 211.671 1.00 76.97  ? 559 TYR A OH  1 
ATOM   2781 N N   . TYR A 1 560 ? 207.791 166.389 204.884 1.00 90.20  ? 560 TYR A N   1 
ATOM   2782 C CA  . TYR A 1 560 ? 207.920 165.324 203.892 1.00 86.19  ? 560 TYR A CA  1 
ATOM   2783 C C   . TYR A 1 560 ? 207.893 165.881 202.473 1.00 83.14  ? 560 TYR A C   1 
ATOM   2784 O O   . TYR A 1 560 ? 208.715 165.500 201.627 1.00 80.01  ? 560 TYR A O   1 
ATOM   2785 C CB  . TYR A 1 560 ? 206.818 164.283 204.091 1.00 85.69  ? 560 TYR A CB  1 
ATOM   2786 C CG  . TYR A 1 560 ? 206.857 163.611 205.445 1.00 87.01  ? 560 TYR A CG  1 
ATOM   2787 C CD1 . TYR A 1 560 ? 208.043 163.091 205.947 1.00 85.40  ? 560 TYR A CD1 1 
ATOM   2788 C CD2 . TYR A 1 560 ? 205.710 163.488 206.216 1.00 85.64  ? 560 TYR A CD2 1 
ATOM   2789 C CE1 . TYR A 1 560 ? 208.087 162.474 207.182 1.00 83.66  ? 560 TYR A CE1 1 
ATOM   2790 C CE2 . TYR A 1 560 ? 205.744 162.872 207.453 1.00 86.42  ? 560 TYR A CE2 1 
ATOM   2791 C CZ  . TYR A 1 560 ? 206.935 162.367 207.931 1.00 85.96  ? 560 TYR A CZ  1 
ATOM   2792 O OH  . TYR A 1 560 ? 206.975 161.752 209.161 1.00 85.41  ? 560 TYR A OH  1 
ATOM   2793 N N   . CYS A 1 561 ? 206.958 166.792 202.194 1.00 81.33  ? 561 CYS A N   1 
ATOM   2794 C CA  . CYS A 1 561 ? 206.904 167.393 200.867 1.00 82.82  ? 561 CYS A CA  1 
ATOM   2795 C C   . CYS A 1 561 ? 208.152 168.222 200.600 1.00 83.20  ? 561 CYS A C   1 
ATOM   2796 O O   . CYS A 1 561 ? 208.603 168.320 199.455 1.00 86.69  ? 561 CYS A O   1 
ATOM   2797 C CB  . CYS A 1 561 ? 205.639 168.238 200.713 1.00 82.64  ? 561 CYS A CB  1 
ATOM   2798 S SG  . CYS A 1 561 ? 205.698 169.866 201.484 1.00 94.47  ? 561 CYS A SG  1 
ATOM   2799 N N   . ALA A 1 562 ? 208.739 168.808 201.647 1.00 65.15  ? 562 ALA A N   1 
ATOM   2800 C CA  . ALA A 1 562 ? 210.014 169.497 201.485 1.00 59.50  ? 562 ALA A CA  1 
ATOM   2801 C C   . ALA A 1 562 ? 211.115 168.528 201.075 1.00 64.25  ? 562 ALA A C   1 
ATOM   2802 O O   . ALA A 1 562 ? 211.937 168.844 200.208 1.00 72.87  ? 562 ALA A O   1 
ATOM   2803 C CB  . ALA A 1 562 ? 210.387 170.219 202.777 1.00 60.39  ? 562 ALA A CB  1 
ATOM   2804 N N   . ILE A 1 563 ? 211.155 167.346 201.696 1.00 66.56  ? 563 ILE A N   1 
ATOM   2805 C CA  . ILE A 1 563 ? 212.146 166.343 201.300 1.00 75.36  ? 563 ILE A CA  1 
ATOM   2806 C C   . ILE A 1 563 ? 211.966 165.956 199.839 1.00 73.56  ? 563 ILE A C   1 
ATOM   2807 O O   . ILE A 1 563 ? 212.935 165.906 199.070 1.00 65.12  ? 563 ILE A O   1 
ATOM   2808 C CB  . ILE A 1 563 ? 212.094 165.105 202.217 1.00 75.51  ? 563 ILE A CB  1 
ATOM   2809 C CG1 . ILE A 1 563 ? 211.925 165.495 203.684 1.00 74.07  ? 563 ILE A CG1 1 
ATOM   2810 C CG2 . ILE A 1 563 ? 213.310 164.223 202.007 1.00 73.69  ? 563 ILE A CG2 1 
ATOM   2811 C CD1 . ILE A 1 563 ? 211.284 164.422 204.532 1.00 76.95  ? 563 ILE A CD1 1 
ATOM   2812 N N   . ILE A 1 564 ? 210.726 165.677 199.430 1.00 77.30  ? 564 ILE A N   1 
ATOM   2813 C CA  . ILE A 1 564 ? 210.495 165.272 198.042 1.00 74.35  ? 564 ILE A CA  1 
ATOM   2814 C C   . ILE A 1 564 ? 210.879 166.395 197.083 1.00 71.16  ? 564 ILE A C   1 
ATOM   2815 O O   . ILE A 1 564 ? 211.526 166.163 196.054 1.00 71.80  ? 564 ILE A O   1 
ATOM   2816 C CB  . ILE A 1 564 ? 209.039 164.819 197.828 1.00 77.17  ? 564 ILE A CB  1 
ATOM   2817 C CG1 . ILE A 1 564 ? 208.534 164.014 199.024 1.00 77.40  ? 564 ILE A CG1 1 
ATOM   2818 C CG2 . ILE A 1 564 ? 208.918 164.004 196.550 1.00 77.26  ? 564 ILE A CG2 1 
ATOM   2819 C CD1 . ILE A 1 564 ? 207.035 164.073 199.210 1.00 77.31  ? 564 ILE A CD1 1 
ATOM   2820 N N   . GLU A 1 565 ? 210.488 167.628 197.407 1.00 65.06  ? 565 GLU A N   1 
ATOM   2821 C CA  . GLU A 1 565 ? 210.777 168.762 196.537 1.00 63.95  ? 565 GLU A CA  1 
ATOM   2822 C C   . GLU A 1 565 ? 212.278 168.997 196.416 1.00 64.66  ? 565 GLU A C   1 
ATOM   2823 O O   . GLU A 1 565 ? 212.790 169.265 195.322 1.00 72.98  ? 565 GLU A O   1 
ATOM   2824 C CB  . GLU A 1 565 ? 210.064 170.004 197.070 1.00 66.35  ? 565 GLU A CB  1 
ATOM   2825 C CG  . GLU A 1 565 ? 210.240 171.255 196.236 1.00 67.68  ? 565 GLU A CG  1 
ATOM   2826 C CD  . GLU A 1 565 ? 211.297 172.178 196.799 1.00 67.38  ? 565 GLU A CD  1 
ATOM   2827 O OE1 . GLU A 1 565 ? 211.968 171.792 197.779 1.00 65.64  ? 565 GLU A OE1 1 
ATOM   2828 O OE2 . GLU A 1 565 ? 211.441 173.299 196.273 1.00 71.76  ? 565 GLU A OE2 1 
ATOM   2829 N N   . ASP A 1 566 ? 213.000 168.903 197.536 1.00 60.94  ? 566 ASP A N   1 
ATOM   2830 C CA  . ASP A 1 566 ? 214.448 169.069 197.500 1.00 64.31  ? 566 ASP A CA  1 
ATOM   2831 C C   . ASP A 1 566 ? 215.106 167.958 196.695 1.00 72.45  ? 566 ASP A C   1 
ATOM   2832 O O   . ASP A 1 566 ? 216.062 168.206 195.954 1.00 70.68  ? 566 ASP A O   1 
ATOM   2833 C CB  . ASP A 1 566 ? 215.008 169.110 198.922 1.00 64.07  ? 566 ASP A CB  1 
ATOM   2834 C CG  . ASP A 1 566 ? 216.448 169.591 198.971 1.00 66.70  ? 566 ASP A CG  1 
ATOM   2835 O OD1 . ASP A 1 566 ? 217.335 168.894 198.435 1.00 68.76  ? 566 ASP A OD1 1 
ATOM   2836 O OD2 . ASP A 1 566 ? 216.694 170.670 199.548 1.00 69.10  ? 566 ASP A OD2 1 
ATOM   2837 N N   . VAL A 1 567 ? 214.610 166.726 196.827 1.00 72.49  ? 567 VAL A N   1 
ATOM   2838 C CA  . VAL A 1 567 ? 215.172 165.619 196.059 1.00 70.29  ? 567 VAL A CA  1 
ATOM   2839 C C   . VAL A 1 567 ? 214.974 165.850 194.566 1.00 63.48  ? 567 VAL A C   1 
ATOM   2840 O O   . VAL A 1 567 ? 215.899 165.662 193.766 1.00 61.04  ? 567 VAL A O   1 
ATOM   2841 C CB  . VAL A 1 567 ? 214.556 164.283 196.515 1.00 71.06  ? 567 VAL A CB  1 
ATOM   2842 C CG1 . VAL A 1 567 ? 214.806 163.199 195.478 1.00 68.41  ? 567 VAL A CG1 1 
ATOM   2843 C CG2 . VAL A 1 567 ? 215.123 163.873 197.864 1.00 66.48  ? 567 VAL A CG2 1 
ATOM   2844 N N   . ILE A 1 568 ? 213.771 166.269 194.166 1.00 62.85  ? 568 ILE A N   1 
ATOM   2845 C CA  . ILE A 1 568 ? 213.503 166.467 192.743 1.00 64.43  ? 568 ILE A CA  1 
ATOM   2846 C C   . ILE A 1 568 ? 214.311 167.636 192.189 1.00 64.56  ? 568 ILE A C   1 
ATOM   2847 O O   . ILE A 1 568 ? 214.958 167.513 191.142 1.00 70.92  ? 568 ILE A O   1 
ATOM   2848 C CB  . ILE A 1 568 ? 211.996 166.652 192.488 1.00 64.16  ? 568 ILE A CB  1 
ATOM   2849 C CG1 . ILE A 1 568 ? 211.197 165.511 193.117 1.00 65.13  ? 568 ILE A CG1 1 
ATOM   2850 C CG2 . ILE A 1 568 ? 211.718 166.742 190.995 1.00 65.96  ? 568 ILE A CG2 1 
ATOM   2851 C CD1 . ILE A 1 568 ? 209.714 165.567 192.823 1.00 68.36  ? 568 ILE A CD1 1 
ATOM   2852 N N   . LEU A 1 569 ? 214.296 168.783 192.870 1.00 58.45  ? 569 LEU A N   1 
ATOM   2853 C CA  . LEU A 1 569 ? 214.919 169.978 192.316 1.00 58.60  ? 569 LEU A CA  1 
ATOM   2854 C C   . LEU A 1 569 ? 216.418 170.058 192.562 1.00 60.41  ? 569 LEU A C   1 
ATOM   2855 O O   . LEU A 1 569 ? 217.081 170.916 191.968 1.00 61.79  ? 569 LEU A O   1 
ATOM   2856 C CB  . LEU A 1 569 ? 214.243 171.235 192.869 1.00 57.70  ? 569 LEU A CB  1 
ATOM   2857 C CG  . LEU A 1 569 ? 212.775 171.367 192.467 1.00 58.23  ? 569 LEU A CG  1 
ATOM   2858 C CD1 . LEU A 1 569 ? 212.086 172.464 193.257 1.00 58.40  ? 569 LEU A CD1 1 
ATOM   2859 C CD2 . LEU A 1 569 ? 212.667 171.619 190.973 1.00 57.51  ? 569 LEU A CD2 1 
ATOM   2860 N N   . ARG A 1 570 ? 216.971 169.197 193.414 1.00 52.87  ? 570 ARG A N   1 
ATOM   2861 C CA  . ARG A 1 570 ? 218.415 169.134 193.581 1.00 49.37  ? 570 ARG A CA  1 
ATOM   2862 C C   . ARG A 1 570 ? 219.092 168.415 192.422 1.00 59.49  ? 570 ARG A C   1 
ATOM   2863 O O   . ARG A 1 570 ? 220.295 168.602 192.206 1.00 64.15  ? 570 ARG A O   1 
ATOM   2864 C CB  . ARG A 1 570 ? 218.749 168.452 194.913 1.00 45.98  ? 570 ARG A CB  1 
ATOM   2865 C CG  . ARG A 1 570 ? 220.224 168.425 195.274 1.00 54.66  ? 570 ARG A CG  1 
ATOM   2866 C CD  . ARG A 1 570 ? 220.856 169.801 195.168 1.00 52.74  ? 570 ARG A CD  1 
ATOM   2867 N NE  . ARG A 1 570 ? 220.619 170.629 196.344 1.00 57.15  ? 570 ARG A NE  1 
ATOM   2868 C CZ  . ARG A 1 570 ? 221.174 171.816 196.545 1.00 57.84  ? 570 ARG A CZ  1 
ATOM   2869 N NH1 . ARG A 1 570 ? 222.020 172.340 195.675 1.00 54.70  ? 570 ARG A NH1 1 
ATOM   2870 N NH2 . ARG A 1 570 ? 220.875 172.495 197.649 1.00 54.67  ? 570 ARG A NH2 1 
ATOM   2871 N N   . PHE A 1 571 ? 218.347 167.612 191.667 1.00 68.32  ? 571 PHE A N   1 
ATOM   2872 C CA  . PHE A 1 571 ? 218.822 167.014 190.426 1.00 64.98  ? 571 PHE A CA  1 
ATOM   2873 C C   . PHE A 1 571 ? 218.744 167.964 189.244 1.00 66.39  ? 571 PHE A C   1 
ATOM   2874 O O   . PHE A 1 571 ? 219.647 167.977 188.407 1.00 70.41  ? 571 PHE A O   1 
ATOM   2875 C CB  . PHE A 1 571 ? 218.010 165.753 190.102 1.00 65.97  ? 571 PHE A CB  1 
ATOM   2876 C CG  . PHE A 1 571 ? 218.382 164.556 190.929 1.00 67.18  ? 571 PHE A CG  1 
ATOM   2877 C CD1 . PHE A 1 571 ? 219.672 164.394 191.395 1.00 61.49  ? 571 PHE A CD1 1 
ATOM   2878 C CD2 . PHE A 1 571 ? 217.442 163.586 191.230 1.00 68.75  ? 571 PHE A CD2 1 
ATOM   2879 C CE1 . PHE A 1 571 ? 220.020 163.297 192.155 1.00 62.39  ? 571 PHE A CE1 1 
ATOM   2880 C CE2 . PHE A 1 571 ? 217.783 162.482 191.989 1.00 65.54  ? 571 PHE A CE2 1 
ATOM   2881 C CZ  . PHE A 1 571 ? 219.075 162.338 192.452 1.00 65.15  ? 571 PHE A CZ  1 
ATOM   2882 N N   . ALA A 1 572 ? 217.680 168.769 189.166 1.00 70.29  ? 572 ALA A N   1 
ATOM   2883 C CA  . ALA A 1 572 ? 217.465 169.613 187.996 1.00 69.58  ? 572 ALA A CA  1 
ATOM   2884 C C   . ALA A 1 572 ? 218.347 170.855 188.007 1.00 73.96  ? 572 ALA A C   1 
ATOM   2885 O O   . ALA A 1 572 ? 218.645 171.408 186.943 1.00 73.63  ? 572 ALA A O   1 
ATOM   2886 C CB  . ALA A 1 572 ? 215.993 170.012 187.906 1.00 67.77  ? 572 ALA A CB  1 
ATOM   2887 N N   . TRP A 1 573 ? 218.760 171.324 189.187 1.00 82.79  ? 573 TRP A N   1 
ATOM   2888 C CA  . TRP A 1 573 ? 219.527 172.565 189.255 1.00 83.29  ? 573 TRP A CA  1 
ATOM   2889 C C   . TRP A 1 573 ? 220.935 172.369 188.700 1.00 80.42  ? 573 TRP A C   1 
ATOM   2890 O O   . TRP A 1 573 ? 221.493 173.277 188.070 1.00 77.66  ? 573 TRP A O   1 
ATOM   2891 C CB  . TRP A 1 573 ? 219.545 173.066 190.702 1.00 78.04  ? 573 TRP A CB  1 
ATOM   2892 C CG  . TRP A 1 573 ? 220.742 172.669 191.498 1.00 80.78  ? 573 TRP A CG  1 
ATOM   2893 C CD1 . TRP A 1 573 ? 220.916 171.511 192.189 1.00 77.02  ? 573 TRP A CD1 1 
ATOM   2894 C CD2 . TRP A 1 573 ? 221.860 173.503 191.831 1.00 83.76  ? 573 TRP A CD2 1 
ATOM   2895 N NE1 . TRP A 1 573 ? 222.123 171.526 192.844 1.00 78.75  ? 573 TRP A NE1 1 
ATOM   2896 C CE2 . TRP A 1 573 ? 222.714 172.746 192.655 1.00 82.50  ? 573 TRP A CE2 1 
ATOM   2897 C CE3 . TRP A 1 573 ? 222.236 174.804 191.484 1.00 79.39  ? 573 TRP A CE3 1 
ATOM   2898 C CZ2 . TRP A 1 573 ? 223.923 173.244 193.135 1.00 80.15  ? 573 TRP A CZ2 1 
ATOM   2899 C CZ3 . TRP A 1 573 ? 223.438 175.298 191.963 1.00 78.34  ? 573 TRP A CZ3 1 
ATOM   2900 C CH2 . TRP A 1 573 ? 224.267 174.518 192.777 1.00 78.46  ? 573 TRP A CH2 1 
ATOM   2901 N N   . THR A 1 574 ? 221.512 171.181 188.892 1.00 78.40  ? 574 THR A N   1 
ATOM   2902 C CA  . THR A 1 574 ? 222.778 170.859 188.239 1.00 81.03  ? 574 THR A CA  1 
ATOM   2903 C C   . THR A 1 574 ? 222.619 170.814 186.723 1.00 81.55  ? 574 THR A C   1 
ATOM   2904 O O   . THR A 1 574 ? 223.513 171.245 185.984 1.00 83.67  ? 574 THR A O   1 
ATOM   2905 C CB  . THR A 1 574 ? 223.322 169.534 188.771 1.00 80.89  ? 574 THR A CB  1 
ATOM   2906 O OG1 . THR A 1 574 ? 222.621 168.449 188.156 1.00 80.70  ? 574 THR A OG1 1 
ATOM   2907 C CG2 . THR A 1 574 ? 223.152 169.453 190.280 1.00 77.56  ? 574 THR A CG2 1 
ATOM   2908 N N   . ILE A 1 575 ? 221.487 170.296 186.238 1.00 80.89  ? 575 ILE A N   1 
ATOM   2909 C CA  . ILE A 1 575 ? 221.197 170.382 184.810 1.00 81.59  ? 575 ILE A CA  1 
ATOM   2910 C C   . ILE A 1 575 ? 221.109 171.838 184.378 1.00 83.39  ? 575 ILE A C   1 
ATOM   2911 O O   . ILE A 1 575 ? 221.511 172.194 183.265 1.00 80.82  ? 575 ILE A O   1 
ATOM   2912 C CB  . ILE A 1 575 ? 219.906 169.618 184.462 1.00 83.14  ? 575 ILE A CB  1 
ATOM   2913 C CG1 . ILE A 1 575 ? 219.800 168.329 185.272 1.00 80.54  ? 575 ILE A CG1 1 
ATOM   2914 C CG2 . ILE A 1 575 ? 219.853 169.313 182.973 1.00 82.66  ? 575 ILE A CG2 1 
ATOM   2915 C CD1 . ILE A 1 575 ? 218.469 167.622 185.115 1.00 77.68  ? 575 ILE A CD1 1 
ATOM   2916 N N   . GLN A 1 576 ? 220.565 172.697 185.243 1.00 87.08  ? 576 GLN A N   1 
ATOM   2917 C CA  . GLN A 1 576 ? 220.500 174.122 184.937 1.00 85.90  ? 576 GLN A CA  1 
ATOM   2918 C C   . GLN A 1 576 ? 221.895 174.711 184.779 1.00 85.53  ? 576 GLN A C   1 
ATOM   2919 O O   . GLN A 1 576 ? 222.129 175.541 183.895 1.00 84.07  ? 576 GLN A O   1 
ATOM   2920 C CB  . GLN A 1 576 ? 219.718 174.858 186.025 1.00 85.39  ? 576 GLN A CB  1 
ATOM   2921 C CG  . GLN A 1 576 ? 219.523 176.339 185.761 1.00 84.91  ? 576 GLN A CG  1 
ATOM   2922 C CD  . GLN A 1 576 ? 220.628 177.183 186.362 1.00 87.44  ? 576 GLN A CD  1 
ATOM   2923 O OE1 . GLN A 1 576 ? 221.468 177.725 185.644 1.00 85.87  ? 576 GLN A OE1 1 
ATOM   2924 N NE2 . GLN A 1 576 ? 220.635 177.296 187.685 1.00 84.70  ? 576 GLN A NE2 1 
ATOM   2925 N N   . ILE A 1 577 ? 222.833 174.302 185.635 1.00 88.76  ? 577 ILE A N   1 
ATOM   2926 C CA  . ILE A 1 577 ? 224.225 174.711 185.436 1.00 89.21  ? 577 ILE A CA  1 
ATOM   2927 C C   . ILE A 1 577 ? 224.739 174.202 184.095 1.00 93.15  ? 577 ILE A C   1 
ATOM   2928 O O   . ILE A 1 577 ? 225.363 174.940 183.323 1.00 90.39  ? 577 ILE A O   1 
ATOM   2929 C CB  . ILE A 1 577 ? 225.127 174.219 186.583 1.00 90.40  ? 577 ILE A CB  1 
ATOM   2930 C CG1 . ILE A 1 577 ? 224.857 174.974 187.878 1.00 85.95  ? 577 ILE A CG1 1 
ATOM   2931 C CG2 . ILE A 1 577 ? 226.596 174.342 186.203 1.00 92.68  ? 577 ILE A CG2 1 
ATOM   2932 C CD1 . ILE A 1 577 ? 224.278 174.108 188.928 1.00 85.52  ? 577 ILE A CD1 1 
ATOM   2933 N N   . SER A 1 578 ? 224.481 172.926 183.801 1.00 102.98 ? 578 SER A N   1 
ATOM   2934 C CA  . SER A 1 578 ? 225.077 172.293 182.628 1.00 102.17 ? 578 SER A CA  1 
ATOM   2935 C C   . SER A 1 578 ? 224.593 172.926 181.328 1.00 102.07 ? 578 SER A C   1 
ATOM   2936 O O   . SER A 1 578 ? 225.396 173.184 180.423 1.00 100.86 ? 578 SER A O   1 
ATOM   2937 C CB  . SER A 1 578 ? 224.774 170.795 182.635 1.00 103.93 ? 578 SER A CB  1 
ATOM   2938 O OG  . SER A 1 578 ? 223.507 170.531 182.058 1.00 106.00 ? 578 SER A OG  1 
ATOM   2939 N N   . ILE A 1 579 ? 223.289 173.189 181.217 1.00 99.55  ? 579 ILE A N   1 
ATOM   2940 C CA  . ILE A 1 579 ? 222.716 173.616 179.942 1.00 98.67  ? 579 ILE A CA  1 
ATOM   2941 C C   . ILE A 1 579 ? 223.248 174.985 179.535 1.00 98.68  ? 579 ILE A C   1 
ATOM   2942 O O   . ILE A 1 579 ? 223.506 175.237 178.352 1.00 100.42 ? 579 ILE A O   1 
ATOM   2943 C CB  . ILE A 1 579 ? 221.178 173.606 180.018 1.00 97.46  ? 579 ILE A CB  1 
ATOM   2944 C CG1 . ILE A 1 579 ? 220.702 174.409 181.230 1.00 99.42  ? 579 ILE A CG1 1 
ATOM   2945 C CG2 . ILE A 1 579 ? 220.658 172.176 180.070 1.00 95.02  ? 579 ILE A CG2 1 
ATOM   2946 C CD1 . ILE A 1 579 ? 219.264 174.178 181.590 1.00 99.55  ? 579 ILE A CD1 1 
ATOM   2947 N N   . THR A 1 580 ? 223.423 175.886 180.498 1.00 101.75 ? 580 THR A N   1 
ATOM   2948 C CA  . THR A 1 580 ? 223.929 177.225 180.224 1.00 102.02 ? 580 THR A CA  1 
ATOM   2949 C C   . THR A 1 580 ? 225.434 177.259 180.000 1.00 105.32 ? 580 THR A C   1 
ATOM   2950 O O   . THR A 1 580 ? 226.011 178.348 179.910 1.00 102.54 ? 580 THR A O   1 
ATOM   2951 C CB  . THR A 1 580 ? 223.554 178.171 181.362 1.00 104.24 ? 580 THR A CB  1 
ATOM   2952 O OG1 . THR A 1 580 ? 224.491 178.017 182.436 1.00 109.96 ? 580 THR A OG1 1 
ATOM   2953 C CG2 . THR A 1 580 ? 222.144 177.893 181.855 1.00 103.96 ? 580 THR A CG2 1 
ATOM   2954 N N   . SER A 1 581 ? 226.076 176.097 179.917 1.00 110.80 ? 581 SER A N   1 
ATOM   2955 C CA  . SER A 1 581 ? 227.470 175.974 179.501 1.00 109.50 ? 581 SER A CA  1 
ATOM   2956 C C   . SER A 1 581 ? 227.562 175.488 178.062 1.00 107.25 ? 581 SER A C   1 
ATOM   2957 O O   . SER A 1 581 ? 228.409 174.655 177.731 1.00 104.01 ? 581 SER A O   1 
ATOM   2958 C CB  . SER A 1 581 ? 228.228 175.042 180.440 1.00 106.02 ? 581 SER A CB  1 
ATOM   2959 O OG  . SER A 1 581 ? 228.002 175.393 181.794 1.00 101.10 ? 581 SER A OG  1 
ATOM   2960 N N   . THR A 1 582 ? 226.674 176.009 177.209 1.00 117.21 ? 582 THR A N   1 
ATOM   2961 C CA  . THR A 1 582 ? 226.455 175.568 175.823 1.00 117.74 ? 582 THR A CA  1 
ATOM   2962 C C   . THR A 1 582 ? 226.587 174.053 175.684 1.00 117.27 ? 582 THR A C   1 
ATOM   2963 O O   . THR A 1 582 ? 227.313 173.532 174.834 1.00 115.23 ? 582 THR A O   1 
ATOM   2964 C CB  . THR A 1 582 ? 227.360 176.308 174.821 1.00 118.66 ? 582 THR A CB  1 
ATOM   2965 O OG1 . THR A 1 582 ? 227.259 175.683 173.535 1.00 119.76 ? 582 THR A OG1 1 
ATOM   2966 C CG2 . THR A 1 582 ? 228.826 176.339 175.241 1.00 117.59 ? 582 THR A CG2 1 
ATOM   2967 N N   . THR A 1 583 ? 225.851 173.341 176.537 1.00 115.88 ? 583 THR A N   1 
ATOM   2968 C CA  . THR A 1 583 ? 225.739 171.892 176.444 1.00 115.87 ? 583 THR A CA  1 
ATOM   2969 C C   . THR A 1 583 ? 224.571 171.474 175.559 1.00 112.27 ? 583 THR A C   1 
ATOM   2970 O O   . THR A 1 583 ? 224.660 170.465 174.850 1.00 111.82 ? 583 THR A O   1 
ATOM   2971 C CB  . THR A 1 583 ? 225.578 171.282 177.840 1.00 116.73 ? 583 THR A CB  1 
ATOM   2972 O OG1 . THR A 1 583 ? 226.532 171.870 178.733 1.00 115.33 ? 583 THR A OG1 1 
ATOM   2973 C CG2 . THR A 1 583 ? 225.795 169.777 177.797 1.00 115.72 ? 583 THR A CG2 1 
ATOM   2974 N N   . LEU A 1 584 ? 223.481 172.236 175.584 1.00 112.98 ? 584 LEU A N   1 
ATOM   2975 C CA  . LEU A 1 584 ? 222.309 172.001 174.743 1.00 115.43 ? 584 LEU A CA  1 
ATOM   2976 C C   . LEU A 1 584 ? 222.073 173.275 173.936 1.00 118.59 ? 584 LEU A C   1 
ATOM   2977 O O   . LEU A 1 584 ? 221.296 174.145 174.337 1.00 119.79 ? 584 LEU A O   1 
ATOM   2978 C CB  . LEU A 1 584 ? 221.091 171.627 175.586 1.00 117.53 ? 584 LEU A CB  1 
ATOM   2979 C CG  . LEU A 1 584 ? 220.527 170.221 175.377 1.00 116.54 ? 584 LEU A CG  1 
ATOM   2980 C CD1 . LEU A 1 584 ? 219.362 169.962 176.320 1.00 116.14 ? 584 LEU A CD1 1 
ATOM   2981 C CD2 . LEU A 1 584 ? 220.105 170.019 173.930 1.00 116.04 ? 584 LEU A CD2 1 
ATOM   2982 N N   . LEU A 1 585 ? 222.751 173.378 172.794 1.00 122.63 ? 585 LEU A N   1 
ATOM   2983 C CA  . LEU A 1 585 ? 222.678 174.555 171.934 1.00 123.06 ? 585 LEU A CA  1 
ATOM   2984 C C   . LEU A 1 585 ? 221.306 174.776 171.289 1.00 123.86 ? 585 LEU A C   1 
ATOM   2985 O O   . LEU A 1 585 ? 220.987 175.926 170.957 1.00 124.56 ? 585 LEU A O   1 
ATOM   2986 C CB  . LEU A 1 585 ? 223.785 174.493 170.868 1.00 122.69 ? 585 LEU A CB  1 
ATOM   2987 C CG  . LEU A 1 585 ? 223.768 173.612 169.612 1.00 123.57 ? 585 LEU A CG  1 
ATOM   2988 C CD1 . LEU A 1 585 ? 222.944 174.224 168.481 1.00 123.72 ? 585 LEU A CD1 1 
ATOM   2989 C CD2 . LEU A 1 585 ? 225.188 173.322 169.146 1.00 122.26 ? 585 LEU A CD2 1 
ATOM   2990 N N   . PRO A 1 586 ? 220.474 173.750 171.065 1.00 119.18 ? 586 PRO A N   1 
ATOM   2991 C CA  . PRO A 1 586 ? 219.104 174.022 170.605 1.00 117.89 ? 586 PRO A CA  1 
ATOM   2992 C C   . PRO A 1 586 ? 218.356 174.946 171.556 1.00 117.24 ? 586 PRO A C   1 
ATOM   2993 O O   . PRO A 1 586 ? 218.733 175.154 172.712 1.00 115.89 ? 586 PRO A O   1 
ATOM   2994 C CB  . PRO A 1 586 ? 218.442 172.640 170.554 1.00 118.14 ? 586 PRO A CB  1 
ATOM   2995 C CG  . PRO A 1 586 ? 219.528 171.650 170.626 1.00 118.30 ? 586 PRO A CG  1 
ATOM   2996 C CD  . PRO A 1 586 ? 220.834 172.333 170.857 1.00 117.48 ? 586 PRO A CD  1 
ATOM   2997 N N   . HIS A 1 587 ? 217.258 175.506 171.041 1.00 109.85 ? 587 HIS A N   1 
ATOM   2998 C CA  . HIS A 1 587 ? 216.455 176.445 171.816 1.00 110.66 ? 587 HIS A CA  1 
ATOM   2999 C C   . HIS A 1 587 ? 215.804 175.794 173.029 1.00 109.61 ? 587 HIS A C   1 
ATOM   3000 O O   . HIS A 1 587 ? 215.372 176.507 173.941 1.00 109.10 ? 587 HIS A O   1 
ATOM   3001 C CB  . HIS A 1 587 ? 215.381 177.075 170.929 1.00 108.73 ? 587 HIS A CB  1 
ATOM   3002 C CG  . HIS A 1 587 ? 215.907 178.113 169.987 1.00 106.88 ? 587 HIS A CG  1 
ATOM   3003 N ND1 . HIS A 1 587 ? 215.723 178.042 168.623 1.00 108.20 ? 587 HIS A ND1 1 
ATOM   3004 C CD2 . HIS A 1 587 ? 216.612 179.246 170.213 1.00 106.62 ? 587 HIS A CD2 1 
ATOM   3005 C CE1 . HIS A 1 587 ? 216.292 179.087 168.049 1.00 109.05 ? 587 HIS A CE1 1 
ATOM   3006 N NE2 . HIS A 1 587 ? 216.838 179.833 168.992 1.00 110.53 ? 587 HIS A NE2 1 
ATOM   3007 N N   . SER A 1 588 ? 215.716 174.461 173.057 1.00 98.70  ? 588 SER A N   1 
ATOM   3008 C CA  . SER A 1 588 ? 215.145 173.784 174.217 1.00 99.25  ? 588 SER A CA  1 
ATOM   3009 C C   . SER A 1 588 ? 215.974 174.025 175.471 1.00 98.41  ? 588 SER A C   1 
ATOM   3010 O O   . SER A 1 588 ? 215.433 174.016 176.583 1.00 95.73  ? 588 SER A O   1 
ATOM   3011 C CB  . SER A 1 588 ? 215.021 172.286 173.943 1.00 101.35 ? 588 SER A CB  1 
ATOM   3012 O OG  . SER A 1 588 ? 214.822 171.563 175.146 1.00 102.94 ? 588 SER A OG  1 
ATOM   3013 N N   . GLY A 1 589 ? 217.281 174.242 175.314 1.00 90.40  ? 589 GLY A N   1 
ATOM   3014 C CA  . GLY A 1 589 ? 218.116 174.524 176.471 1.00 92.13  ? 589 GLY A CA  1 
ATOM   3015 C C   . GLY A 1 589 ? 217.721 175.811 177.170 1.00 95.19  ? 589 GLY A C   1 
ATOM   3016 O O   . GLY A 1 589 ? 217.613 175.858 178.397 1.00 96.88  ? 589 GLY A O   1 
ATOM   3017 N N   . ASP A 1 590 ? 217.497 176.873 176.394 1.00 89.72  ? 590 ASP A N   1 
ATOM   3018 C CA  . ASP A 1 590 ? 217.086 178.142 176.986 1.00 87.50  ? 590 ASP A CA  1 
ATOM   3019 C C   . ASP A 1 590 ? 215.698 178.041 177.611 1.00 83.83  ? 590 ASP A C   1 
ATOM   3020 O O   . ASP A 1 590 ? 215.460 178.592 178.693 1.00 86.68  ? 590 ASP A O   1 
ATOM   3021 C CB  . ASP A 1 590 ? 217.131 179.249 175.934 1.00 86.86  ? 590 ASP A CB  1 
ATOM   3022 C CG  . ASP A 1 590 ? 218.495 179.384 175.289 1.00 91.22  ? 590 ASP A CG  1 
ATOM   3023 O OD1 . ASP A 1 590 ? 219.443 179.806 175.984 1.00 86.83  ? 590 ASP A OD1 1 
ATOM   3024 O OD2 . ASP A 1 590 ? 218.620 179.069 174.087 1.00 92.41  ? 590 ASP A OD2 1 
ATOM   3025 N N   . ILE A 1 591 ? 214.774 177.338 176.950 1.00 74.91  ? 591 ILE A N   1 
ATOM   3026 C CA  . ILE A 1 591 ? 213.447 177.112 177.523 1.00 76.42  ? 591 ILE A CA  1 
ATOM   3027 C C   . ILE A 1 591 ? 213.564 176.423 178.876 1.00 79.27  ? 591 ILE A C   1 
ATOM   3028 O O   . ILE A 1 591 ? 212.991 176.873 179.877 1.00 78.80  ? 591 ILE A O   1 
ATOM   3029 C CB  . ILE A 1 591 ? 212.576 176.286 176.557 1.00 78.41  ? 591 ILE A CB  1 
ATOM   3030 C CG1 . ILE A 1 591 ? 212.135 177.114 175.349 1.00 80.31  ? 591 ILE A CG1 1 
ATOM   3031 C CG2 . ILE A 1 591 ? 211.360 175.726 177.282 1.00 76.39  ? 591 ILE A CG2 1 
ATOM   3032 C CD1 . ILE A 1 591 ? 211.400 178.380 175.722 1.00 81.66  ? 591 ILE A CD1 1 
ATOM   3033 N N   . ILE A 1 592 ? 214.320 175.326 178.928 1.00 80.30  ? 592 ILE A N   1 
ATOM   3034 C CA  . ILE A 1 592 ? 214.386 174.547 180.157 1.00 81.61  ? 592 ILE A CA  1 
ATOM   3035 C C   . ILE A 1 592 ? 215.150 175.301 181.242 1.00 80.04  ? 592 ILE A C   1 
ATOM   3036 O O   . ILE A 1 592 ? 214.826 175.179 182.428 1.00 80.90  ? 592 ILE A O   1 
ATOM   3037 C CB  . ILE A 1 592 ? 214.975 173.150 179.869 1.00 82.64  ? 592 ILE A CB  1 
ATOM   3038 C CG1 . ILE A 1 592 ? 214.519 172.146 180.929 1.00 78.56  ? 592 ILE A CG1 1 
ATOM   3039 C CG2 . ILE A 1 592 ? 216.484 173.188 179.746 1.00 82.12  ? 592 ILE A CG2 1 
ATOM   3040 C CD1 . ILE A 1 592 ? 213.078 171.710 180.776 1.00 78.14  ? 592 ILE A CD1 1 
ATOM   3041 N N   . ALA A 1 593 ? 216.137 176.120 180.869 1.00 73.95  ? 593 ALA A N   1 
ATOM   3042 C CA  . ALA A 1 593 ? 216.837 176.931 181.862 1.00 73.66  ? 593 ALA A CA  1 
ATOM   3043 C C   . ALA A 1 593 ? 215.919 177.996 182.449 1.00 78.95  ? 593 ALA A C   1 
ATOM   3044 O O   . ALA A 1 593 ? 215.891 178.206 183.670 1.00 83.81  ? 593 ALA A O   1 
ATOM   3045 C CB  . ALA A 1 593 ? 218.075 177.574 181.237 1.00 67.99  ? 593 ALA A CB  1 
ATOM   3046 N N   . THR A 1 594 ? 215.163 178.687 181.590 1.00 69.54  ? 594 THR A N   1 
ATOM   3047 C CA  . THR A 1 594 ? 214.247 179.716 182.068 1.00 62.47  ? 594 THR A CA  1 
ATOM   3048 C C   . THR A 1 594 ? 213.110 179.114 182.884 1.00 64.12  ? 594 THR A C   1 
ATOM   3049 O O   . THR A 1 594 ? 212.534 179.797 183.737 1.00 69.35  ? 594 THR A O   1 
ATOM   3050 C CB  . THR A 1 594 ? 213.694 180.515 180.887 1.00 67.67  ? 594 THR A CB  1 
ATOM   3051 O OG1 . THR A 1 594 ? 214.758 180.821 179.978 1.00 69.35  ? 594 THR A OG1 1 
ATOM   3052 C CG2 . THR A 1 594 ? 213.067 181.816 181.366 1.00 71.72  ? 594 THR A CG2 1 
ATOM   3053 N N   . VAL A 1 595 ? 212.769 177.849 182.635 1.00 59.02  ? 595 VAL A N   1 
ATOM   3054 C CA  . VAL A 1 595 ? 211.750 177.204 183.456 1.00 63.18  ? 595 VAL A CA  1 
ATOM   3055 C C   . VAL A 1 595 ? 212.333 176.704 184.778 1.00 66.95  ? 595 VAL A C   1 
ATOM   3056 O O   . VAL A 1 595 ? 211.654 176.742 185.811 1.00 69.00  ? 595 VAL A O   1 
ATOM   3057 C CB  . VAL A 1 595 ? 211.074 176.068 182.669 1.00 64.77  ? 595 VAL A CB  1 
ATOM   3058 C CG1 . VAL A 1 595 ? 210.128 175.281 183.562 1.00 68.08  ? 595 VAL A CG1 1 
ATOM   3059 C CG2 . VAL A 1 595 ? 210.312 176.635 181.485 1.00 66.92  ? 595 VAL A CG2 1 
ATOM   3060 N N   . PHE A 1 596 ? 213.590 176.259 184.786 1.00 74.41  ? 596 PHE A N   1 
ATOM   3061 C CA  . PHE A 1 596 ? 214.152 175.628 185.973 1.00 68.86  ? 596 PHE A CA  1 
ATOM   3062 C C   . PHE A 1 596 ? 214.750 176.618 186.963 1.00 69.87  ? 596 PHE A C   1 
ATOM   3063 O O   . PHE A 1 596 ? 214.807 176.314 188.161 1.00 70.79  ? 596 PHE A O   1 
ATOM   3064 C CB  . PHE A 1 596 ? 215.222 174.609 185.572 1.00 64.85  ? 596 PHE A CB  1 
ATOM   3065 C CG  . PHE A 1 596 ? 214.697 173.212 185.420 1.00 71.07  ? 596 PHE A CG  1 
ATOM   3066 C CD1 . PHE A 1 596 ? 213.748 172.716 186.298 1.00 70.43  ? 596 PHE A CD1 1 
ATOM   3067 C CD2 . PHE A 1 596 ? 215.156 172.391 184.406 1.00 75.67  ? 596 PHE A CD2 1 
ATOM   3068 C CE1 . PHE A 1 596 ? 213.260 171.431 186.162 1.00 71.18  ? 596 PHE A CE1 1 
ATOM   3069 C CE2 . PHE A 1 596 ? 214.674 171.103 184.266 1.00 78.30  ? 596 PHE A CE2 1 
ATOM   3070 C CZ  . PHE A 1 596 ? 213.725 170.623 185.145 1.00 78.16  ? 596 PHE A CZ  1 
ATOM   3071 N N   . ALA A 1 597 ? 215.207 177.785 186.505 1.00 59.06  ? 597 ALA A N   1 
ATOM   3072 C CA  . ALA A 1 597 ? 215.768 178.761 187.439 1.00 59.37  ? 597 ALA A CA  1 
ATOM   3073 C C   . ALA A 1 597 ? 214.761 179.214 188.493 1.00 59.59  ? 597 ALA A C   1 
ATOM   3074 O O   . ALA A 1 597 ? 215.126 179.259 189.683 1.00 55.70  ? 597 ALA A O   1 
ATOM   3075 C CB  . ALA A 1 597 ? 216.353 179.944 186.661 1.00 49.99  ? 597 ALA A CB  1 
ATOM   3076 N N   . PRO A 1 598 ? 213.512 179.568 188.154 1.00 51.93  ? 598 PRO A N   1 
ATOM   3077 C CA  . PRO A 1 598 ? 212.532 179.834 189.220 1.00 48.72  ? 598 PRO A CA  1 
ATOM   3078 C C   . PRO A 1 598 ? 212.321 178.649 190.142 1.00 57.62  ? 598 PRO A C   1 
ATOM   3079 O O   . PRO A 1 598 ? 212.114 178.833 191.348 1.00 65.48  ? 598 PRO A O   1 
ATOM   3080 C CB  . PRO A 1 598 ? 211.258 180.182 188.439 1.00 52.25  ? 598 PRO A CB  1 
ATOM   3081 C CG  . PRO A 1 598 ? 211.750 180.709 187.148 1.00 57.60  ? 598 PRO A CG  1 
ATOM   3082 C CD  . PRO A 1 598 ? 212.953 179.880 186.826 1.00 54.08  ? 598 PRO A CD  1 
ATOM   3083 N N   . LEU A 1 599 ? 212.364 177.430 189.604 1.00 53.80  ? 599 LEU A N   1 
ATOM   3084 C CA  . LEU A 1 599 ? 212.257 176.249 190.453 1.00 54.43  ? 599 LEU A CA  1 
ATOM   3085 C C   . LEU A 1 599 ? 213.446 176.151 191.400 1.00 52.68  ? 599 LEU A C   1 
ATOM   3086 O O   . LEU A 1 599 ? 213.293 175.748 192.559 1.00 56.70  ? 599 LEU A O   1 
ATOM   3087 C CB  . LEU A 1 599 ? 212.142 174.990 189.594 1.00 56.94  ? 599 LEU A CB  1 
ATOM   3088 C CG  . LEU A 1 599 ? 210.723 174.510 189.273 1.00 59.45  ? 599 LEU A CG  1 
ATOM   3089 C CD1 . LEU A 1 599 ? 210.015 174.034 190.532 1.00 54.50  ? 599 LEU A CD1 1 
ATOM   3090 C CD2 . LEU A 1 599 ? 209.911 175.589 188.572 1.00 62.18  ? 599 LEU A CD2 1 
ATOM   3091 N N   . GLU A 1 600 ? 214.639 176.520 190.926 1.00 52.34  ? 600 GLU A N   1 
ATOM   3092 C CA  . GLU A 1 600 ? 215.807 176.543 191.800 1.00 55.38  ? 600 GLU A CA  1 
ATOM   3093 C C   . GLU A 1 600 ? 215.640 177.568 192.915 1.00 65.31  ? 600 GLU A C   1 
ATOM   3094 O O   . GLU A 1 600 ? 215.996 177.305 194.070 1.00 67.56  ? 600 GLU A O   1 
ATOM   3095 C CB  . GLU A 1 600 ? 217.065 176.835 190.983 1.00 61.31  ? 600 GLU A CB  1 
ATOM   3096 C CG  . GLU A 1 600 ? 218.320 177.026 191.817 1.00 68.96  ? 600 GLU A CG  1 
ATOM   3097 C CD  . GLU A 1 600 ? 219.509 177.464 190.984 1.00 74.52  ? 600 GLU A CD  1 
ATOM   3098 O OE1 . GLU A 1 600 ? 219.349 177.627 189.757 1.00 70.10  ? 600 GLU A OE1 1 
ATOM   3099 O OE2 . GLU A 1 600 ? 220.602 177.647 191.558 1.00 78.88  ? 600 GLU A OE2 1 
ATOM   3100 N N   . VAL A 1 601 ? 215.094 178.742 192.590 1.00 56.16  ? 601 VAL A N   1 
ATOM   3101 C CA  . VAL A 1 601 ? 214.874 179.756 193.620 1.00 42.61  ? 601 VAL A CA  1 
ATOM   3102 C C   . VAL A 1 601 ? 213.833 179.282 194.630 1.00 37.20  ? 601 VAL A C   1 
ATOM   3103 O O   . VAL A 1 601 ? 213.960 179.529 195.834 1.00 51.10  ? 601 VAL A O   1 
ATOM   3104 C CB  . VAL A 1 601 ? 214.478 181.096 192.976 1.00 36.69  ? 601 VAL A CB  1 
ATOM   3105 C CG1 . VAL A 1 601 ? 214.223 182.143 194.046 1.00 33.82  ? 601 VAL A CG1 1 
ATOM   3106 C CG2 . VAL A 1 601 ? 215.570 181.565 192.033 1.00 47.31  ? 601 VAL A CG2 1 
ATOM   3107 N N   . PHE A 1 602 ? 212.791 178.595 194.159 1.00 29.28  ? 602 PHE A N   1 
ATOM   3108 C CA  . PHE A 1 602 ? 211.792 178.036 195.069 1.00 30.61  ? 602 PHE A CA  1 
ATOM   3109 C C   . PHE A 1 602 ? 212.404 176.978 195.983 1.00 47.22  ? 602 PHE A C   1 
ATOM   3110 O O   . PHE A 1 602 ? 212.099 176.921 197.185 1.00 50.74  ? 602 PHE A O   1 
ATOM   3111 C CB  . PHE A 1 602 ? 210.634 177.455 194.257 1.00 30.43  ? 602 PHE A CB  1 
ATOM   3112 C CG  . PHE A 1 602 ? 209.617 176.725 195.080 1.00 37.26  ? 602 PHE A CG  1 
ATOM   3113 C CD1 . PHE A 1 602 ? 208.789 177.410 195.951 1.00 51.98  ? 602 PHE A CD1 1 
ATOM   3114 C CD2 . PHE A 1 602 ? 209.478 175.353 194.972 1.00 38.42  ? 602 PHE A CD2 1 
ATOM   3115 C CE1 . PHE A 1 602 ? 207.848 176.739 196.706 1.00 55.75  ? 602 PHE A CE1 1 
ATOM   3116 C CE2 . PHE A 1 602 ? 208.540 174.676 195.723 1.00 41.70  ? 602 PHE A CE2 1 
ATOM   3117 C CZ  . PHE A 1 602 ? 207.723 175.370 196.592 1.00 52.75  ? 602 PHE A CZ  1 
ATOM   3118 N N   . ARG A 1 603 ? 213.268 176.126 195.426 1.00 50.27  ? 603 ARG A N   1 
ATOM   3119 C CA  . ARG A 1 603 ? 213.969 175.134 196.234 1.00 50.66  ? 603 ARG A CA  1 
ATOM   3120 C C   . ARG A 1 603 ? 214.827 175.807 197.294 1.00 44.68  ? 603 ARG A C   1 
ATOM   3121 O O   . ARG A 1 603 ? 214.870 175.368 198.448 1.00 54.88  ? 603 ARG A O   1 
ATOM   3122 C CB  . ARG A 1 603 ? 214.828 174.241 195.340 1.00 50.36  ? 603 ARG A CB  1 
ATOM   3123 C CG  . ARG A 1 603 ? 215.314 172.975 196.019 1.00 43.18  ? 603 ARG A CG  1 
ATOM   3124 C CD  . ARG A 1 603 ? 216.596 172.473 195.376 1.00 52.68  ? 603 ARG A CD  1 
ATOM   3125 N NE  . ARG A 1 603 ? 217.645 173.488 195.370 1.00 51.19  ? 603 ARG A NE  1 
ATOM   3126 C CZ  . ARG A 1 603 ? 218.273 173.933 196.450 1.00 50.59  ? 603 ARG A CZ  1 
ATOM   3127 N NH1 . ARG A 1 603 ? 217.998 173.462 197.655 1.00 43.71  ? 603 ARG A NH1 1 
ATOM   3128 N NH2 . ARG A 1 603 ? 219.206 174.870 196.316 1.00 54.63  ? 603 ARG A NH2 1 
ATOM   3129 N N   . ARG A 1 604 ? 215.523 176.878 196.914 1.00 23.63  ? 604 ARG A N   1 
ATOM   3130 C CA  . ARG A 1 604 ? 216.330 177.615 197.877 1.00 23.67  ? 604 ARG A CA  1 
ATOM   3131 C C   . ARG A 1 604 ? 215.465 178.276 198.944 1.00 31.26  ? 604 ARG A C   1 
ATOM   3132 O O   . ARG A 1 604 ? 215.881 178.380 200.099 1.00 35.21  ? 604 ARG A O   1 
ATOM   3133 C CB  . ARG A 1 604 ? 217.184 178.649 197.148 1.00 24.83  ? 604 ARG A CB  1 
ATOM   3134 C CG  . ARG A 1 604 ? 217.954 179.570 198.059 1.00 32.53  ? 604 ARG A CG  1 
ATOM   3135 C CD  . ARG A 1 604 ? 218.886 178.803 198.983 1.00 28.47  ? 604 ARG A CD  1 
ATOM   3136 N NE  . ARG A 1 604 ? 219.697 177.827 198.266 1.00 36.80  ? 604 ARG A NE  1 
ATOM   3137 C CZ  . ARG A 1 604 ? 220.733 177.186 198.789 1.00 39.46  ? 604 ARG A CZ  1 
ATOM   3138 N NH1 . ARG A 1 604 ? 221.114 177.393 200.037 1.00 25.48  ? 604 ARG A NH1 1 
ATOM   3139 N NH2 . ARG A 1 604 ? 221.403 176.317 198.039 1.00 43.33  ? 604 ARG A NH2 1 
ATOM   3140 N N   . PHE A 1 605 ? 214.262 178.719 198.579 1.00 40.35  ? 605 PHE A N   1 
ATOM   3141 C CA  . PHE A 1 605 ? 213.330 179.284 199.552 1.00 33.15  ? 605 PHE A CA  1 
ATOM   3142 C C   . PHE A 1 605 ? 212.917 178.244 200.594 1.00 39.82  ? 605 PHE A C   1 
ATOM   3143 O O   . PHE A 1 605 ? 212.935 178.512 201.806 1.00 53.13  ? 605 PHE A O   1 
ATOM   3144 C CB  . PHE A 1 605 ? 212.122 179.851 198.798 1.00 37.68  ? 605 PHE A CB  1 
ATOM   3145 C CG  . PHE A 1 605 ? 210.799 179.629 199.472 1.00 42.76  ? 605 PHE A CG  1 
ATOM   3146 C CD1 . PHE A 1 605 ? 210.387 180.438 200.512 1.00 41.33  ? 605 PHE A CD1 1 
ATOM   3147 C CD2 . PHE A 1 605 ? 209.953 178.622 199.040 1.00 44.09  ? 605 PHE A CD2 1 
ATOM   3148 C CE1 . PHE A 1 605 ? 209.164 180.237 201.122 1.00 41.68  ? 605 PHE A CE1 1 
ATOM   3149 C CE2 . PHE A 1 605 ? 208.730 178.416 199.646 1.00 34.24  ? 605 PHE A CE2 1 
ATOM   3150 C CZ  . PHE A 1 605 ? 208.335 179.224 200.688 1.00 33.46  ? 605 PHE A CZ  1 
ATOM   3151 N N   . VAL A 1 606 ? 212.566 177.039 200.137 1.00 30.62  ? 606 VAL A N   1 
ATOM   3152 C CA  . VAL A 1 606 ? 212.216 175.967 201.071 1.00 37.41  ? 606 VAL A CA  1 
ATOM   3153 C C   . VAL A 1 606 ? 213.418 175.598 201.936 1.00 37.41  ? 606 VAL A C   1 
ATOM   3154 O O   . VAL A 1 606 ? 213.293 175.368 203.152 1.00 37.53  ? 606 VAL A O   1 
ATOM   3155 C CB  . VAL A 1 606 ? 211.675 174.746 200.304 1.00 35.33  ? 606 VAL A CB  1 
ATOM   3156 C CG1 . VAL A 1 606 ? 211.356 173.614 201.267 1.00 37.61  ? 606 VAL A CG1 1 
ATOM   3157 C CG2 . VAL A 1 606 ? 210.445 175.127 199.500 1.00 33.63  ? 606 VAL A CG2 1 
ATOM   3158 N N   . TRP A 1 607 ? 214.599 175.524 201.318 1.00 41.93  ? 607 TRP A N   1 
ATOM   3159 C CA  . TRP A 1 607 ? 215.809 175.218 202.068 1.00 36.30  ? 607 TRP A CA  1 
ATOM   3160 C C   . TRP A 1 607 ? 216.085 176.281 203.116 1.00 34.21  ? 607 TRP A C   1 
ATOM   3161 O O   . TRP A 1 607 ? 216.570 175.961 204.199 1.00 47.38  ? 607 TRP A O   1 
ATOM   3162 C CB  . TRP A 1 607 ? 217.004 175.086 201.122 1.00 42.07  ? 607 TRP A CB  1 
ATOM   3163 C CG  . TRP A 1 607 ? 218.332 174.977 201.825 1.00 37.45  ? 607 TRP A CG  1 
ATOM   3164 C CD1 . TRP A 1 607 ? 219.006 173.827 202.112 1.00 43.80  ? 607 TRP A CD1 1 
ATOM   3165 C CD2 . TRP A 1 607 ? 219.143 176.051 202.324 1.00 36.26  ? 607 TRP A CD2 1 
ATOM   3166 N NE1 . TRP A 1 607 ? 220.182 174.115 202.759 1.00 46.16  ? 607 TRP A NE1 1 
ATOM   3167 C CE2 . TRP A 1 607 ? 220.289 175.473 202.902 1.00 39.60  ? 607 TRP A CE2 1 
ATOM   3168 C CE3 . TRP A 1 607 ? 219.009 177.442 202.341 1.00 40.23  ? 607 TRP A CE3 1 
ATOM   3169 C CZ2 . TRP A 1 607 ? 221.295 176.236 203.488 1.00 45.94  ? 607 TRP A CZ2 1 
ATOM   3170 C CZ3 . TRP A 1 607 ? 220.009 178.198 202.925 1.00 39.05  ? 607 TRP A CZ3 1 
ATOM   3171 C CH2 . TRP A 1 607 ? 221.136 177.594 203.489 1.00 45.80  ? 607 TRP A CH2 1 
ATOM   3172 N N   . ASN A 1 608 ? 215.808 177.547 202.806 1.00 26.53  ? 608 ASN A N   1 
ATOM   3173 C CA  . ASN A 1 608 ? 215.990 178.611 203.787 1.00 36.71  ? 608 ASN A CA  1 
ATOM   3174 C C   . ASN A 1 608 ? 215.048 178.425 204.966 1.00 34.87  ? 608 ASN A C   1 
ATOM   3175 O O   . ASN A 1 608 ? 215.466 178.520 206.128 1.00 35.63  ? 608 ASN A O   1 
ATOM   3176 C CB  . ASN A 1 608 ? 215.770 179.972 203.128 1.00 40.97  ? 608 ASN A CB  1 
ATOM   3177 C CG  . ASN A 1 608 ? 216.545 181.078 203.808 1.00 44.40  ? 608 ASN A CG  1 
ATOM   3178 O OD1 . ASN A 1 608 ? 217.343 180.827 204.710 1.00 42.40  ? 608 ASN A OD1 1 
ATOM   3179 N ND2 . ASN A 1 608 ? 216.310 182.312 203.382 1.00 34.41  ? 608 ASN A ND2 1 
ATOM   3180 N N   . PHE A 1 609 ? 213.770 178.152 204.678 1.00 38.05  ? 609 PHE A N   1 
ATOM   3181 C CA  . PHE A 1 609 ? 212.823 177.786 205.730 1.00 40.35  ? 609 PHE A CA  1 
ATOM   3182 C C   . PHE A 1 609 ? 213.429 176.760 206.680 1.00 53.60  ? 609 PHE A C   1 
ATOM   3183 O O   . PHE A 1 609 ? 213.609 177.015 207.881 1.00 58.61  ? 609 PHE A O   1 
ATOM   3184 C CB  . PHE A 1 609 ? 211.536 177.220 205.117 1.00 33.67  ? 609 PHE A CB  1 
ATOM   3185 C CG  . PHE A 1 609 ? 210.344 178.126 205.234 1.00 38.35  ? 609 PHE A CG  1 
ATOM   3186 C CD1 . PHE A 1 609 ? 210.203 179.221 204.411 1.00 44.03  ? 609 PHE A CD1 1 
ATOM   3187 C CD2 . PHE A 1 609 ? 209.355 177.869 206.165 1.00 44.50  ? 609 PHE A CD2 1 
ATOM   3188 C CE1 . PHE A 1 609 ? 209.106 180.053 204.518 1.00 42.95  ? 609 PHE A CE1 1 
ATOM   3189 C CE2 . PHE A 1 609 ? 208.256 178.695 206.278 1.00 52.97  ? 609 PHE A CE2 1 
ATOM   3190 C CZ  . PHE A 1 609 ? 208.132 179.789 205.452 1.00 49.83  ? 609 PHE A CZ  1 
ATOM   3191 N N   . PHE A 1 610 ? 213.780 175.595 206.138 1.00 47.20  ? 610 PHE A N   1 
ATOM   3192 C CA  . PHE A 1 610 ? 214.152 174.485 207.010 1.00 29.01  ? 610 PHE A CA  1 
ATOM   3193 C C   . PHE A 1 610 ? 215.541 174.649 207.615 1.00 23.47  ? 610 PHE A C   1 
ATOM   3194 O O   . PHE A 1 610 ? 215.769 174.202 208.744 1.00 37.29  ? 610 PHE A O   1 
ATOM   3195 C CB  . PHE A 1 610 ? 214.023 173.166 206.252 1.00 35.83  ? 610 PHE A CB  1 
ATOM   3196 C CG  . PHE A 1 610 ? 212.600 172.730 206.071 1.00 40.31  ? 610 PHE A CG  1 
ATOM   3197 C CD1 . PHE A 1 610 ? 211.815 173.284 205.075 1.00 45.93  ? 610 PHE A CD1 1 
ATOM   3198 C CD2 . PHE A 1 610 ? 212.037 171.792 206.916 1.00 36.98  ? 610 PHE A CD2 1 
ATOM   3199 C CE1 . PHE A 1 610 ? 210.500 172.900 204.917 1.00 38.78  ? 610 PHE A CE1 1 
ATOM   3200 C CE2 . PHE A 1 610 ? 210.724 171.401 206.759 1.00 44.87  ? 610 PHE A CE2 1 
ATOM   3201 C CZ  . PHE A 1 610 ? 209.954 171.956 205.759 1.00 44.00  ? 610 PHE A CZ  1 
ATOM   3202 N N   . ARG A 1 611 ? 216.467 175.305 206.914 1.00 25.18  ? 611 ARG A N   1 
ATOM   3203 C CA  . ARG A 1 611 ? 217.780 175.575 207.485 1.00 18.82  ? 611 ARG A CA  1 
ATOM   3204 C C   . ARG A 1 611 ? 217.680 176.520 208.672 1.00 36.33  ? 611 ARG A C   1 
ATOM   3205 O O   . ARG A 1 611 ? 218.311 176.283 209.706 1.00 51.16  ? 611 ARG A O   1 
ATOM   3206 C CB  . ARG A 1 611 ? 218.712 176.150 206.417 1.00 34.27  ? 611 ARG A CB  1 
ATOM   3207 C CG  . ARG A 1 611 ? 219.976 176.798 206.968 1.00 23.14  ? 611 ARG A CG  1 
ATOM   3208 C CD  . ARG A 1 611 ? 220.820 175.812 207.763 1.00 34.75  ? 611 ARG A CD  1 
ATOM   3209 N NE  . ARG A 1 611 ? 222.165 176.315 208.013 1.00 44.39  ? 611 ARG A NE  1 
ATOM   3210 C CZ  . ARG A 1 611 ? 223.234 175.547 208.173 1.00 51.64  ? 611 ARG A CZ  1 
ATOM   3211 N NH1 . ARG A 1 611 ? 223.155 174.229 208.101 1.00 48.01  ? 611 ARG A NH1 1 
ATOM   3212 N NH2 . ARG A 1 611 ? 224.411 176.114 208.418 1.00 52.68  ? 611 ARG A NH2 1 
ATOM   3213 N N   . LEU A 1 612 ? 216.896 177.597 208.552 1.00 48.87  ? 612 LEU A N   1 
ATOM   3214 C CA  . LEU A 1 612 ? 216.724 178.483 209.698 1.00 36.26  ? 612 LEU A CA  1 
ATOM   3215 C C   . LEU A 1 612 ? 216.026 177.767 210.847 1.00 38.13  ? 612 LEU A C   1 
ATOM   3216 O O   . LEU A 1 612 ? 216.410 177.933 212.014 1.00 42.94  ? 612 LEU A O   1 
ATOM   3217 C CB  . LEU A 1 612 ? 215.949 179.736 209.295 1.00 37.88  ? 612 LEU A CB  1 
ATOM   3218 C CG  . LEU A 1 612 ? 216.801 180.959 208.956 1.00 37.74  ? 612 LEU A CG  1 
ATOM   3219 C CD1 . LEU A 1 612 ? 217.421 181.513 210.227 1.00 31.92  ? 612 LEU A CD1 1 
ATOM   3220 C CD2 . LEU A 1 612 ? 217.872 180.634 207.930 1.00 44.43  ? 612 LEU A CD2 1 
ATOM   3221 N N   . GLU A 1 613 ? 215.010 176.956 210.537 1.00 50.26  ? 613 GLU A N   1 
ATOM   3222 C CA  . GLU A 1 613 ? 214.310 176.237 211.597 1.00 56.89  ? 613 GLU A CA  1 
ATOM   3223 C C   . GLU A 1 613 ? 215.252 175.293 212.337 1.00 48.31  ? 613 GLU A C   1 
ATOM   3224 O O   . GLU A 1 613 ? 215.221 175.209 213.570 1.00 54.95  ? 613 GLU A O   1 
ATOM   3225 C CB  . GLU A 1 613 ? 213.121 175.472 211.020 1.00 57.56  ? 613 GLU A CB  1 
ATOM   3226 C CG  . GLU A 1 613 ? 212.163 174.971 212.082 1.00 62.63  ? 613 GLU A CG  1 
ATOM   3227 C CD  . GLU A 1 613 ? 211.746 173.538 211.857 1.00 59.90  ? 613 GLU A CD  1 
ATOM   3228 O OE1 . GLU A 1 613 ? 212.373 172.860 211.018 1.00 60.53  ? 613 GLU A OE1 1 
ATOM   3229 O OE2 . GLU A 1 613 ? 210.793 173.085 212.525 1.00 65.40  ? 613 GLU A OE2 1 
ATOM   3230 N N   . ASN A 1 614 ? 216.096 174.567 211.599 1.00 42.00  ? 614 ASN A N   1 
ATOM   3231 C CA  . ASN A 1 614 ? 217.062 173.680 212.237 1.00 41.77  ? 614 ASN A CA  1 
ATOM   3232 C C   . ASN A 1 614 ? 218.103 174.466 213.024 1.00 43.27  ? 614 ASN A C   1 
ATOM   3233 O O   . ASN A 1 614 ? 218.496 174.059 214.124 1.00 61.12  ? 614 ASN A O   1 
ATOM   3234 C CB  . ASN A 1 614 ? 217.732 172.790 211.188 1.00 48.60  ? 614 ASN A CB  1 
ATOM   3235 C CG  . ASN A 1 614 ? 218.801 171.886 211.778 1.00 50.18  ? 614 ASN A CG  1 
ATOM   3236 O OD1 . ASN A 1 614 ? 219.927 172.319 212.020 1.00 48.45  ? 614 ASN A OD1 1 
ATOM   3237 N ND2 . ASN A 1 614 ? 218.443 170.636 212.048 1.00 56.85  ? 614 ASN A ND2 1 
ATOM   3238 N N   . GLU A 1 615 ? 218.565 175.593 212.476 1.00 35.10  ? 615 GLU A N   1 
ATOM   3239 C CA  . GLU A 1 615 ? 219.594 176.379 213.147 1.00 41.40  ? 615 GLU A CA  1 
ATOM   3240 C C   . GLU A 1 615 ? 219.099 176.906 214.486 1.00 56.20  ? 615 GLU A C   1 
ATOM   3241 O O   . GLU A 1 615 ? 219.852 176.936 215.466 1.00 59.98  ? 615 GLU A O   1 
ATOM   3242 C CB  . GLU A 1 615 ? 220.040 177.531 212.247 1.00 40.20  ? 615 GLU A CB  1 
ATOM   3243 C CG  . GLU A 1 615 ? 220.946 178.540 212.928 1.00 43.22  ? 615 GLU A CG  1 
ATOM   3244 C CD  . GLU A 1 615 ? 222.399 178.113 212.927 1.00 48.74  ? 615 GLU A CD  1 
ATOM   3245 O OE1 . GLU A 1 615 ? 222.704 177.044 212.359 1.00 55.55  ? 615 GLU A OE1 1 
ATOM   3246 O OE2 . GLU A 1 615 ? 223.236 178.848 213.492 1.00 49.44  ? 615 GLU A OE2 1 
ATOM   3247 N N   . HIS A 1 616 ? 217.836 177.334 214.548 1.00 53.53  ? 616 HIS A N   1 
ATOM   3248 C CA  . HIS A 1 616 ? 217.285 177.774 215.826 1.00 46.98  ? 616 HIS A CA  1 
ATOM   3249 C C   . HIS A 1 616 ? 217.249 176.632 216.835 1.00 49.69  ? 616 HIS A C   1 
ATOM   3250 O O   . HIS A 1 616 ? 217.580 176.821 218.011 1.00 51.80  ? 616 HIS A O   1 
ATOM   3251 C CB  . HIS A 1 616 ? 215.886 178.348 215.631 1.00 42.45  ? 616 HIS A CB  1 
ATOM   3252 C CG  . HIS A 1 616 ? 215.125 178.534 216.906 1.00 49.65  ? 616 HIS A CG  1 
ATOM   3253 N ND1 . HIS A 1 616 ? 213.935 177.890 217.164 1.00 50.85  ? 616 HIS A ND1 1 
ATOM   3254 C CD2 . HIS A 1 616 ? 215.385 179.295 217.996 1.00 54.38  ? 616 HIS A CD2 1 
ATOM   3255 C CE1 . HIS A 1 616 ? 213.494 178.244 218.358 1.00 51.86  ? 616 HIS A CE1 1 
ATOM   3256 N NE2 . HIS A 1 616 ? 214.356 179.096 218.884 1.00 55.83  ? 616 HIS A NE2 1 
ATOM   3257 N N   . LEU A 1 617 ? 216.854 175.438 216.391 1.00 48.46  ? 617 LEU A N   1 
ATOM   3258 C CA  . LEU A 1 617 ? 216.685 174.318 217.311 1.00 51.19  ? 617 LEU A CA  1 
ATOM   3259 C C   . LEU A 1 617 ? 218.032 173.787 217.786 1.00 52.46  ? 617 LEU A C   1 
ATOM   3260 O O   . LEU A 1 617 ? 218.352 173.843 218.979 1.00 56.18  ? 617 LEU A O   1 
ATOM   3261 C CB  . LEU A 1 617 ? 215.873 173.212 216.634 1.00 55.78  ? 617 LEU A CB  1 
ATOM   3262 C CG  . LEU A 1 617 ? 214.378 173.164 216.947 1.00 50.30  ? 617 LEU A CG  1 
ATOM   3263 C CD1 . LEU A 1 617 ? 213.757 174.541 216.808 1.00 49.84  ? 617 LEU A CD1 1 
ATOM   3264 C CD2 . LEU A 1 617 ? 213.685 172.176 216.026 1.00 55.77  ? 617 LEU A CD2 1 
ATOM   3265 N N   . ASN A 1 618 ? 218.838 173.269 216.862 1.00 51.74  ? 618 ASN A N   1 
ATOM   3266 C CA  . ASN A 1 618 ? 220.167 172.748 217.168 1.00 47.39  ? 618 ASN A CA  1 
ATOM   3267 C C   . ASN A 1 618 ? 221.187 173.606 216.434 1.00 45.06  ? 618 ASN A C   1 
ATOM   3268 O O   . ASN A 1 618 ? 221.117 173.746 215.209 1.00 57.16  ? 618 ASN A O   1 
ATOM   3269 C CB  . ASN A 1 618 ? 220.290 171.280 216.763 1.00 45.49  ? 618 ASN A CB  1 
ATOM   3270 C CG  . ASN A 1 618 ? 218.972 170.538 216.850 1.00 49.64  ? 618 ASN A CG  1 
ATOM   3271 O OD1 . ASN A 1 618 ? 218.462 170.036 215.848 1.00 41.15  ? 618 ASN A OD1 1 
ATOM   3272 N ND2 . ASN A 1 618 ? 218.413 170.464 218.051 1.00 50.71  ? 618 ASN A ND2 1 
ATOM   3273 N N   . ASN A 1 619 ? 222.129 174.180 217.182 1.00 42.55  ? 619 ASN A N   1 
ATOM   3274 C CA  . ASN A 1 619 ? 223.155 175.029 216.591 1.00 47.92  ? 619 ASN A CA  1 
ATOM   3275 C C   . ASN A 1 619 ? 223.958 174.243 215.562 1.00 55.02  ? 619 ASN A C   1 
ATOM   3276 O O   . ASN A 1 619 ? 224.698 173.319 215.915 1.00 65.85  ? 619 ASN A O   1 
ATOM   3277 C CB  . ASN A 1 619 ? 224.074 175.594 217.678 1.00 54.31  ? 619 ASN A CB  1 
ATOM   3278 C CG  . ASN A 1 619 ? 225.095 176.578 217.133 1.00 52.47  ? 619 ASN A CG  1 
ATOM   3279 O OD1 . ASN A 1 619 ? 225.056 176.952 215.961 1.00 49.66  ? 619 ASN A OD1 1 
ATOM   3280 N ND2 . ASN A 1 619 ? 226.017 177.003 217.989 1.00 56.49  ? 619 ASN A ND2 1 
ATOM   3281 N N   . CYS A 1 620 ? 223.818 174.605 214.291 1.00 56.30  ? 620 CYS A N   1 
ATOM   3282 C CA  . CYS A 1 620 ? 224.497 173.930 213.196 1.00 56.68  ? 620 CYS A CA  1 
ATOM   3283 C C   . CYS A 1 620 ? 225.595 174.828 212.646 1.00 53.39  ? 620 CYS A C   1 
ATOM   3284 O O   . CYS A 1 620 ? 225.399 176.035 212.477 1.00 51.73  ? 620 CYS A O   1 
ATOM   3285 C CB  . CYS A 1 620 ? 223.514 173.560 212.083 1.00 48.31  ? 620 CYS A CB  1 
ATOM   3286 S SG  . CYS A 1 620 ? 222.809 171.902 212.231 1.00 71.35  ? 620 CYS A SG  1 
ATOM   3287 N N   . GLY A 1 621 ? 226.751 174.232 212.367 1.00 66.17  ? 621 GLY A N   1 
ATOM   3288 C CA  . GLY A 1 621 ? 227.895 174.991 211.912 1.00 65.23  ? 621 GLY A CA  1 
ATOM   3289 C C   . GLY A 1 621 ? 228.669 175.689 213.005 1.00 68.15  ? 621 GLY A C   1 
ATOM   3290 O O   . GLY A 1 621 ? 229.655 176.370 212.702 1.00 70.80  ? 621 GLY A O   1 
ATOM   3291 N N   . GLU A 1 622 ? 228.257 175.535 214.266 1.00 73.78  ? 622 GLU A N   1 
ATOM   3292 C CA  . GLU A 1 622 ? 228.939 176.142 215.410 1.00 78.41  ? 622 GLU A CA  1 
ATOM   3293 C C   . GLU A 1 622 ? 229.058 177.656 215.238 1.00 77.50  ? 622 GLU A C   1 
ATOM   3294 O O   . GLU A 1 622 ? 230.122 178.249 215.427 1.00 79.59  ? 622 GLU A O   1 
ATOM   3295 C CB  . GLU A 1 622 ? 230.310 175.495 215.633 1.00 77.14  ? 622 GLU A CB  1 
ATOM   3296 C CG  . GLU A 1 622 ? 230.931 175.764 217.000 1.00 77.13  ? 622 GLU A CG  1 
ATOM   3297 C CD  . GLU A 1 622 ? 230.158 175.114 218.130 1.00 78.22  ? 622 GLU A CD  1 
ATOM   3298 O OE1 . GLU A 1 622 ? 229.858 173.906 218.029 1.00 80.56  ? 622 GLU A OE1 1 
ATOM   3299 O OE2 . GLU A 1 622 ? 229.850 175.811 219.120 1.00 75.37  ? 622 GLU A OE2 1 
ATOM   3300 N N   . PHE A 1 623 ? 227.948 178.291 214.854 1.00 63.29  ? 623 PHE A N   1 
ATOM   3301 C CA  . PHE A 1 623 ? 227.945 179.741 214.693 1.00 63.80  ? 623 PHE A CA  1 
ATOM   3302 C C   . PHE A 1 623 ? 227.813 180.438 216.042 1.00 68.16  ? 623 PHE A C   1 
ATOM   3303 O O   . PHE A 1 623 ? 228.693 181.204 216.450 1.00 73.96  ? 623 PHE A O   1 
ATOM   3304 C CB  . PHE A 1 623 ? 226.818 180.163 213.749 1.00 59.27  ? 623 PHE A CB  1 
ATOM   3305 C CG  . PHE A 1 623 ? 227.135 179.955 212.296 1.00 60.19  ? 623 PHE A CG  1 
ATOM   3306 C CD1 . PHE A 1 623 ? 227.969 180.833 211.623 1.00 60.38  ? 623 PHE A CD1 1 
ATOM   3307 C CD2 . PHE A 1 623 ? 226.598 178.885 211.602 1.00 64.86  ? 623 PHE A CD2 1 
ATOM   3308 C CE1 . PHE A 1 623 ? 228.263 180.644 210.287 1.00 63.90  ? 623 PHE A CE1 1 
ATOM   3309 C CE2 . PHE A 1 623 ? 226.889 178.692 210.265 1.00 65.56  ? 623 PHE A CE2 1 
ATOM   3310 C CZ  . PHE A 1 623 ? 227.722 179.573 209.607 1.00 67.05  ? 623 PHE A CZ  1 
ATOM   3311 N N   . ARG A 1 624 ? 226.716 180.185 216.748 1.00 70.24  ? 624 ARG A N   1 
ATOM   3312 C CA  . ARG A 1 624 ? 226.523 180.752 218.072 1.00 66.00  ? 624 ARG A CA  1 
ATOM   3313 C C   . ARG A 1 624 ? 227.387 180.025 219.095 1.00 66.46  ? 624 ARG A C   1 
ATOM   3314 O O   . ARG A 1 624 ? 227.768 178.866 218.909 1.00 68.03  ? 624 ARG A O   1 
ATOM   3315 C CB  . ARG A 1 624 ? 225.052 180.674 218.482 1.00 64.69  ? 624 ARG A CB  1 
ATOM   3316 C CG  . ARG A 1 624 ? 224.112 181.435 217.563 1.00 63.96  ? 624 ARG A CG  1 
ATOM   3317 C CD  . ARG A 1 624 ? 222.731 181.582 218.182 1.00 65.93  ? 624 ARG A CD  1 
ATOM   3318 N NE  . ARG A 1 624 ? 222.127 180.292 218.491 1.00 67.83  ? 624 ARG A NE  1 
ATOM   3319 C CZ  . ARG A 1 624 ? 221.631 179.457 217.587 1.00 65.35  ? 624 ARG A CZ  1 
ATOM   3320 N NH1 . ARG A 1 624 ? 221.644 179.748 216.297 1.00 60.75  ? 624 ARG A NH1 1 
ATOM   3321 N NH2 . ARG A 1 624 ? 221.108 178.302 217.989 1.00 63.30  ? 624 ARG A NH2 1 
ATOM   3322 N N   . ALA A 1 625 ? 227.701 180.728 220.186 1.00 79.62  ? 625 ALA A N   1 
ATOM   3323 C CA  . ALA A 1 625 ? 228.496 180.123 221.249 1.00 83.62  ? 625 ALA A CA  1 
ATOM   3324 C C   . ALA A 1 625 ? 227.746 178.992 221.940 1.00 85.50  ? 625 ALA A C   1 
ATOM   3325 O O   . ALA A 1 625 ? 228.359 177.992 222.331 1.00 81.32  ? 625 ALA A O   1 
ATOM   3326 C CB  . ALA A 1 625 ? 228.910 181.185 222.268 1.00 82.79  ? 625 ALA A CB  1 
ATOM   3327 N N   . VAL A 1 626 ? 226.434 179.129 222.099 1.00 94.47  ? 626 VAL A N   1 
ATOM   3328 C CA  . VAL A 1 626 ? 225.623 178.100 222.737 1.00 95.61  ? 626 VAL A CA  1 
ATOM   3329 C C   . VAL A 1 626 ? 225.563 176.852 221.864 1.00 87.15  ? 626 VAL A C   1 
ATOM   3330 O O   . VAL A 1 626 ? 224.867 175.889 222.187 1.00 84.11  ? 626 VAL A O   1 
ATOM   3331 C CB  . VAL A 1 626 ? 224.206 178.617 223.039 1.00 93.10  ? 626 VAL A CB  1 
ATOM   3332 C CG1 . VAL A 1 626 ? 224.272 179.878 223.888 1.00 88.80  ? 626 VAL A CG1 1 
ATOM   3333 C CG2 . VAL A 1 626 ? 223.450 178.878 221.745 1.00 86.82  ? 626 VAL A CG2 1 
ATOM   3334 N N   . ALA B 1 226 ? 185.923 202.546 217.732 1.00 113.10 ? 226 ALA B N   1 
ATOM   3335 C CA  . ALA B 1 226 ? 186.817 202.849 216.621 1.00 114.36 ? 226 ALA B CA  1 
ATOM   3336 C C   . ALA B 1 226 ? 187.948 201.829 216.536 1.00 113.69 ? 226 ALA B C   1 
ATOM   3337 O O   . ALA B 1 226 ? 189.124 202.192 216.536 1.00 113.05 ? 226 ALA B O   1 
ATOM   3338 C CB  . ALA B 1 226 ? 187.379 204.255 216.761 1.00 114.06 ? 226 ALA B CB  1 
ATOM   3339 N N   . GLN B 1 227 ? 187.582 200.555 216.471 1.00 111.56 ? 227 GLN B N   1 
ATOM   3340 C CA  . GLN B 1 227 ? 188.579 199.498 216.364 1.00 113.75 ? 227 GLN B CA  1 
ATOM   3341 C C   . GLN B 1 227 ? 189.290 199.590 215.019 1.00 113.80 ? 227 GLN B C   1 
ATOM   3342 O O   . GLN B 1 227 ? 188.630 199.748 213.985 1.00 112.33 ? 227 GLN B O   1 
ATOM   3343 C CB  . GLN B 1 227 ? 187.925 198.128 216.524 1.00 115.24 ? 227 GLN B CB  1 
ATOM   3344 C CG  . GLN B 1 227 ? 187.282 197.901 217.883 1.00 112.90 ? 227 GLN B CG  1 
ATOM   3345 C CD  . GLN B 1 227 ? 186.652 196.528 218.008 1.00 112.49 ? 227 GLN B CD  1 
ATOM   3346 O OE1 . GLN B 1 227 ? 186.748 195.703 217.100 1.00 114.95 ? 227 GLN B OE1 1 
ATOM   3347 N NE2 . GLN B 1 227 ? 186.003 196.275 219.139 1.00 109.42 ? 227 GLN B NE2 1 
ATOM   3348 N N   . PRO B 1 228 ? 190.619 199.508 214.987 1.00 95.71  ? 228 PRO B N   1 
ATOM   3349 C CA  . PRO B 1 228 ? 191.329 199.588 213.707 1.00 92.63  ? 228 PRO B CA  1 
ATOM   3350 C C   . PRO B 1 228 ? 190.994 198.411 212.806 1.00 92.42  ? 228 PRO B C   1 
ATOM   3351 O O   . PRO B 1 228 ? 190.729 197.297 213.266 1.00 90.69  ? 228 PRO B O   1 
ATOM   3352 C CB  . PRO B 1 228 ? 192.806 199.572 214.117 1.00 89.99  ? 228 PRO B CB  1 
ATOM   3353 C CG  . PRO B 1 228 ? 192.820 198.913 215.455 1.00 90.91  ? 228 PRO B CG  1 
ATOM   3354 C CD  . PRO B 1 228 ? 191.536 199.314 216.122 1.00 92.88  ? 228 PRO B CD  1 
ATOM   3355 N N   . ALA B 1 229 ? 191.007 198.675 211.502 1.00 84.54  ? 229 ALA B N   1 
ATOM   3356 C CA  . ALA B 1 229 ? 190.695 197.642 210.531 1.00 80.73  ? 229 ALA B CA  1 
ATOM   3357 C C   . ALA B 1 229 ? 191.819 196.609 210.469 1.00 76.42  ? 229 ALA B C   1 
ATOM   3358 O O   . ALA B 1 229 ? 192.987 196.934 210.696 1.00 77.90  ? 229 ALA B O   1 
ATOM   3359 C CB  . ALA B 1 229 ? 190.477 198.255 209.151 1.00 78.58  ? 229 ALA B CB  1 
ATOM   3360 N N   . PRO B 1 230 ? 191.489 195.352 210.171 1.00 63.95  ? 230 PRO B N   1 
ATOM   3361 C CA  . PRO B 1 230 ? 192.533 194.329 210.043 1.00 64.65  ? 230 PRO B CA  1 
ATOM   3362 C C   . PRO B 1 230 ? 193.473 194.641 208.890 1.00 64.93  ? 230 PRO B C   1 
ATOM   3363 O O   . PRO B 1 230 ? 193.095 195.278 207.904 1.00 69.55  ? 230 PRO B O   1 
ATOM   3364 C CB  . PRO B 1 230 ? 191.743 193.040 209.787 1.00 59.48  ? 230 PRO B CB  1 
ATOM   3365 C CG  . PRO B 1 230 ? 190.353 193.330 210.254 1.00 62.63  ? 230 PRO B CG  1 
ATOM   3366 C CD  . PRO B 1 230 ? 190.137 194.790 210.018 1.00 60.70  ? 230 PRO B CD  1 
ATOM   3367 N N   . ALA B 1 231 ? 194.722 194.189 209.031 1.00 49.38  ? 231 ALA B N   1 
ATOM   3368 C CA  . ALA B 1 231 ? 195.709 194.407 207.979 1.00 52.34  ? 231 ALA B CA  1 
ATOM   3369 C C   . ALA B 1 231 ? 195.316 193.706 206.685 1.00 48.85  ? 231 ALA B C   1 
ATOM   3370 O O   . ALA B 1 231 ? 195.705 194.147 205.598 1.00 45.66  ? 231 ALA B O   1 
ATOM   3371 C CB  . ALA B 1 231 ? 197.087 193.937 208.444 1.00 52.68  ? 231 ALA B CB  1 
ATOM   3372 N N   . TRP B 1 232 ? 194.550 192.618 206.780 1.00 48.31  ? 232 TRP B N   1 
ATOM   3373 C CA  . TRP B 1 232 ? 194.078 191.942 205.576 1.00 50.42  ? 232 TRP B CA  1 
ATOM   3374 C C   . TRP B 1 232 ? 193.152 192.843 204.767 1.00 55.85  ? 232 TRP B C   1 
ATOM   3375 O O   . TRP B 1 232 ? 193.234 192.884 203.534 1.00 46.53  ? 232 TRP B O   1 
ATOM   3376 C CB  . TRP B 1 232 ? 193.371 190.640 205.949 1.00 50.92  ? 232 TRP B CB  1 
ATOM   3377 C CG  . TRP B 1 232 ? 193.480 189.576 204.900 1.00 55.04  ? 232 TRP B CG  1 
ATOM   3378 C CD1 . TRP B 1 232 ? 192.453 188.988 204.225 1.00 55.68  ? 232 TRP B CD1 1 
ATOM   3379 C CD2 . TRP B 1 232 ? 194.682 188.969 204.411 1.00 52.53  ? 232 TRP B CD2 1 
ATOM   3380 N NE1 . TRP B 1 232 ? 192.939 188.055 203.342 1.00 53.59  ? 232 TRP B NE1 1 
ATOM   3381 C CE2 . TRP B 1 232 ? 194.305 188.024 203.438 1.00 53.41  ? 232 TRP B CE2 1 
ATOM   3382 C CE3 . TRP B 1 232 ? 196.039 189.133 204.701 1.00 47.52  ? 232 TRP B CE3 1 
ATOM   3383 C CZ2 . TRP B 1 232 ? 195.236 187.247 202.752 1.00 53.12  ? 232 TRP B CZ2 1 
ATOM   3384 C CZ3 . TRP B 1 232 ? 196.960 188.362 204.019 1.00 48.17  ? 232 TRP B CZ3 1 
ATOM   3385 C CH2 . TRP B 1 232 ? 196.555 187.431 203.057 1.00 49.72  ? 232 TRP B CH2 1 
ATOM   3386 N N   . THR B 1 233 ? 192.264 193.573 205.445 1.00 57.21  ? 233 THR B N   1 
ATOM   3387 C CA  . THR B 1 233 ? 191.379 194.500 204.746 1.00 42.68  ? 233 THR B CA  1 
ATOM   3388 C C   . THR B 1 233 ? 192.168 195.626 204.088 1.00 46.39  ? 233 THR B C   1 
ATOM   3389 O O   . THR B 1 233 ? 191.853 196.040 202.965 1.00 62.42  ? 233 THR B O   1 
ATOM   3390 C CB  . THR B 1 233 ? 190.339 195.062 205.715 1.00 47.30  ? 233 THR B CB  1 
ATOM   3391 O OG1 . THR B 1 233 ? 189.485 194.003 206.167 1.00 62.02  ? 233 THR B OG1 1 
ATOM   3392 C CG2 . THR B 1 233 ? 189.490 196.127 205.038 1.00 51.52  ? 233 THR B CG2 1 
ATOM   3393 N N   . THR B 1 234 ? 193.194 196.137 204.774 1.00 28.43  ? 234 THR B N   1 
ATOM   3394 C CA  . THR B 1 234 ? 194.037 197.170 204.182 1.00 23.22  ? 234 THR B CA  1 
ATOM   3395 C C   . THR B 1 234 ? 194.766 196.646 202.951 1.00 32.09  ? 234 THR B C   1 
ATOM   3396 O O   . THR B 1 234 ? 194.867 197.342 201.933 1.00 31.50  ? 234 THR B O   1 
ATOM   3397 C CB  . THR B 1 234 ? 195.035 197.694 205.213 1.00 26.14  ? 234 THR B CB  1 
ATOM   3398 O OG1 . THR B 1 234 ? 194.387 197.823 206.484 1.00 30.82  ? 234 THR B OG1 1 
ATOM   3399 C CG2 . THR B 1 234 ? 195.567 199.050 204.789 1.00 27.42  ? 234 THR B CG2 1 
ATOM   3400 N N   . PHE B 1 235 ? 195.274 195.415 203.021 1.00 40.29  ? 235 PHE B N   1 
ATOM   3401 C CA  . PHE B 1 235 ? 195.911 194.820 201.852 1.00 37.30  ? 235 PHE B CA  1 
ATOM   3402 C C   . PHE B 1 235 ? 194.917 194.661 200.710 1.00 38.95  ? 235 PHE B C   1 
ATOM   3403 O O   . PHE B 1 235 ? 195.254 194.905 199.547 1.00 49.09  ? 235 PHE B O   1 
ATOM   3404 C CB  . PHE B 1 235 ? 196.530 193.471 202.218 1.00 43.74  ? 235 PHE B CB  1 
ATOM   3405 C CG  . PHE B 1 235 ? 196.781 192.581 201.035 1.00 41.02  ? 235 PHE B CG  1 
ATOM   3406 C CD1 . PHE B 1 235 ? 197.882 192.784 200.222 1.00 29.92  ? 235 PHE B CD1 1 
ATOM   3407 C CD2 . PHE B 1 235 ? 195.920 191.537 200.740 1.00 36.99  ? 235 PHE B CD2 1 
ATOM   3408 C CE1 . PHE B 1 235 ? 198.116 191.970 199.134 1.00 29.41  ? 235 PHE B CE1 1 
ATOM   3409 C CE2 . PHE B 1 235 ? 196.150 190.720 199.653 1.00 29.28  ? 235 PHE B CE2 1 
ATOM   3410 C CZ  . PHE B 1 235 ? 197.250 190.936 198.849 1.00 36.77  ? 235 PHE B CZ  1 
ATOM   3411 N N   . ARG B 1 236 ? 193.686 194.251 201.023 1.00 30.71  ? 236 ARG B N   1 
ATOM   3412 C CA  . ARG B 1 236 ? 192.680 194.066 199.982 1.00 40.51  ? 236 ARG B CA  1 
ATOM   3413 C C   . ARG B 1 236 ? 192.330 195.386 199.304 1.00 37.50  ? 236 ARG B C   1 
ATOM   3414 O O   . ARG B 1 236 ? 192.225 195.450 198.072 1.00 42.17  ? 236 ARG B O   1 
ATOM   3415 C CB  . ARG B 1 236 ? 191.428 193.418 200.572 1.00 37.41  ? 236 ARG B CB  1 
ATOM   3416 C CG  . ARG B 1 236 ? 191.176 192.003 200.084 1.00 39.25  ? 236 ARG B CG  1 
ATOM   3417 C CD  . ARG B 1 236 ? 189.945 191.404 200.740 1.00 34.68  ? 236 ARG B CD  1 
ATOM   3418 N NE  . ARG B 1 236 ? 189.983 191.538 202.191 1.00 46.93  ? 236 ARG B NE  1 
ATOM   3419 C CZ  . ARG B 1 236 ? 189.031 191.110 203.009 1.00 51.75  ? 236 ARG B CZ  1 
ATOM   3420 N NH1 . ARG B 1 236 ? 187.946 190.508 202.550 1.00 50.39  ? 236 ARG B NH1 1 
ATOM   3421 N NH2 . ARG B 1 236 ? 189.172 191.291 204.319 1.00 47.77  ? 236 ARG B NH2 1 
ATOM   3422 N N   . VAL B 1 237 ? 192.143 196.452 200.087 1.00 37.73  ? 237 VAL B N   1 
ATOM   3423 C CA  . VAL B 1 237 ? 191.799 197.734 199.479 1.00 37.07  ? 237 VAL B CA  1 
ATOM   3424 C C   . VAL B 1 237 ? 192.978 198.279 198.683 1.00 39.62  ? 237 VAL B C   1 
ATOM   3425 O O   . VAL B 1 237 ? 192.795 198.880 197.620 1.00 44.41  ? 237 VAL B O   1 
ATOM   3426 C CB  . VAL B 1 237 ? 191.298 198.746 200.529 1.00 14.93  ? 237 VAL B CB  1 
ATOM   3427 C CG1 . VAL B 1 237 ? 192.267 198.890 201.667 1.00 36.94  ? 237 VAL B CG1 1 
ATOM   3428 C CG2 . VAL B 1 237 ? 191.063 200.095 199.881 1.00 26.58  ? 237 VAL B CG2 1 
ATOM   3429 N N   . GLY B 1 238 ? 194.206 198.069 199.166 1.00 31.38  ? 238 GLY B N   1 
ATOM   3430 C CA  . GLY B 1 238 ? 195.364 198.463 198.379 1.00 38.44  ? 238 GLY B CA  1 
ATOM   3431 C C   . GLY B 1 238 ? 195.451 197.718 197.060 1.00 40.34  ? 238 GLY B C   1 
ATOM   3432 O O   . GLY B 1 238 ? 195.744 198.310 196.018 1.00 35.40  ? 238 GLY B O   1 
ATOM   3433 N N   . LEU B 1 239 ? 195.190 196.409 197.088 1.00 28.32  ? 239 LEU B N   1 
ATOM   3434 C CA  . LEU B 1 239 ? 195.190 195.613 195.865 1.00 27.77  ? 239 LEU B CA  1 
ATOM   3435 C C   . LEU B 1 239 ? 194.143 196.122 194.885 1.00 39.40  ? 239 LEU B C   1 
ATOM   3436 O O   . LEU B 1 239 ? 194.419 196.291 193.690 1.00 44.44  ? 239 LEU B O   1 
ATOM   3437 C CB  . LEU B 1 239 ? 194.942 194.144 196.211 1.00 24.89  ? 239 LEU B CB  1 
ATOM   3438 C CG  . LEU B 1 239 ? 194.512 193.191 195.095 1.00 34.08  ? 239 LEU B CG  1 
ATOM   3439 C CD1 . LEU B 1 239 ? 195.719 192.637 194.362 1.00 42.19  ? 239 LEU B CD1 1 
ATOM   3440 C CD2 . LEU B 1 239 ? 193.660 192.065 195.657 1.00 31.15  ? 239 LEU B CD2 1 
ATOM   3441 N N   . PHE B 1 240 ? 192.931 196.380 195.381 1.00 33.71  ? 240 PHE B N   1 
ATOM   3442 C CA  . PHE B 1 240 ? 191.870 196.871 194.510 1.00 23.37  ? 240 PHE B CA  1 
ATOM   3443 C C   . PHE B 1 240 ? 192.211 198.244 193.945 1.00 25.09  ? 240 PHE B C   1 
ATOM   3444 O O   . PHE B 1 240 ? 191.958 198.515 192.767 1.00 40.19  ? 240 PHE B O   1 
ATOM   3445 C CB  . PHE B 1 240 ? 190.544 196.905 195.266 1.00 29.00  ? 240 PHE B CB  1 
ATOM   3446 C CG  . PHE B 1 240 ? 189.957 195.545 195.512 1.00 31.58  ? 240 PHE B CG  1 
ATOM   3447 C CD1 . PHE B 1 240 ? 190.016 194.566 194.537 1.00 31.50  ? 240 PHE B CD1 1 
ATOM   3448 C CD2 . PHE B 1 240 ? 189.345 195.246 196.717 1.00 37.95  ? 240 PHE B CD2 1 
ATOM   3449 C CE1 . PHE B 1 240 ? 189.478 193.313 194.758 1.00 33.11  ? 240 PHE B CE1 1 
ATOM   3450 C CE2 . PHE B 1 240 ? 188.805 193.995 196.944 1.00 31.63  ? 240 PHE B CE2 1 
ATOM   3451 C CZ  . PHE B 1 240 ? 188.871 193.028 195.963 1.00 28.91  ? 240 PHE B CZ  1 
ATOM   3452 N N   . CYS B 1 241 ? 192.799 199.120 194.764 1.00 29.91  ? 241 CYS B N   1 
ATOM   3453 C CA  . CYS B 1 241 ? 193.172 200.448 194.289 1.00 34.68  ? 241 CYS B CA  1 
ATOM   3454 C C   . CYS B 1 241 ? 194.252 200.375 193.217 1.00 32.69  ? 241 CYS B C   1 
ATOM   3455 O O   . CYS B 1 241 ? 194.200 201.109 192.224 1.00 39.68  ? 241 CYS B O   1 
ATOM   3456 C CB  . CYS B 1 241 ? 193.641 201.311 195.460 1.00 45.18  ? 241 CYS B CB  1 
ATOM   3457 S SG  . CYS B 1 241 ? 194.716 202.684 194.987 1.00 58.54  ? 241 CYS B SG  1 
ATOM   3458 N N   . GLY B 1 242 ? 195.245 199.503 193.403 1.00 26.06  ? 242 GLY B N   1 
ATOM   3459 C CA  . GLY B 1 242 ? 196.279 199.357 192.390 1.00 38.61  ? 242 GLY B CA  1 
ATOM   3460 C C   . GLY B 1 242 ? 195.739 198.799 191.087 1.00 34.50  ? 242 GLY B C   1 
ATOM   3461 O O   . GLY B 1 242 ? 196.057 199.303 190.001 1.00 31.40  ? 242 GLY B O   1 
ATOM   3462 N N   . ILE B 1 243 ? 194.904 197.761 191.176 1.00 32.40  ? 243 ILE B N   1 
ATOM   3463 C CA  . ILE B 1 243 ? 194.278 197.219 189.975 1.00 32.85  ? 243 ILE B CA  1 
ATOM   3464 C C   . ILE B 1 243 ? 193.449 198.296 189.287 1.00 39.74  ? 243 ILE B C   1 
ATOM   3465 O O   . ILE B 1 243 ? 193.475 198.428 188.058 1.00 36.50  ? 243 ILE B O   1 
ATOM   3466 C CB  . ILE B 1 243 ? 193.433 195.980 190.323 1.00 31.32  ? 243 ILE B CB  1 
ATOM   3467 C CG1 . ILE B 1 243 ? 194.321 194.865 190.877 1.00 32.92  ? 243 ILE B CG1 1 
ATOM   3468 C CG2 . ILE B 1 243 ? 192.692 195.476 189.096 1.00 36.45  ? 243 ILE B CG2 1 
ATOM   3469 C CD1 . ILE B 1 243 ? 193.575 193.585 191.187 1.00 36.70  ? 243 ILE B CD1 1 
ATOM   3470 N N   . PHE B 1 244 ? 192.729 199.104 190.070 1.00 40.92  ? 244 PHE B N   1 
ATOM   3471 C CA  . PHE B 1 244 ? 191.876 200.141 189.499 1.00 27.99  ? 244 PHE B CA  1 
ATOM   3472 C C   . PHE B 1 244 ? 192.693 201.212 188.793 1.00 36.18  ? 244 PHE B C   1 
ATOM   3473 O O   . PHE B 1 244 ? 192.339 201.646 187.694 1.00 54.04  ? 244 PHE B O   1 
ATOM   3474 C CB  . PHE B 1 244 ? 191.005 200.765 190.589 1.00 38.02  ? 244 PHE B CB  1 
ATOM   3475 C CG  . PHE B 1 244 ? 190.005 201.756 190.066 1.00 38.25  ? 244 PHE B CG  1 
ATOM   3476 C CD1 . PHE B 1 244 ? 188.977 201.349 189.233 1.00 39.90  ? 244 PHE B CD1 1 
ATOM   3477 C CD2 . PHE B 1 244 ? 190.094 203.095 190.405 1.00 42.81  ? 244 PHE B CD2 1 
ATOM   3478 C CE1 . PHE B 1 244 ? 188.058 202.258 188.749 1.00 40.10  ? 244 PHE B CE1 1 
ATOM   3479 C CE2 . PHE B 1 244 ? 189.177 204.008 189.924 1.00 45.91  ? 244 PHE B CE2 1 
ATOM   3480 C CZ  . PHE B 1 244 ? 188.157 203.589 189.095 1.00 42.76  ? 244 PHE B CZ  1 
ATOM   3481 N N   . ILE B 1 245 ? 193.787 201.662 189.410 1.00 34.02  ? 245 ILE B N   1 
ATOM   3482 C CA  . ILE B 1 245 ? 194.563 202.738 188.799 1.00 37.31  ? 245 ILE B CA  1 
ATOM   3483 C C   . ILE B 1 245 ? 195.252 202.246 187.531 1.00 45.19  ? 245 ILE B C   1 
ATOM   3484 O O   . ILE B 1 245 ? 195.305 202.960 186.520 1.00 53.99  ? 245 ILE B O   1 
ATOM   3485 C CB  . ILE B 1 245 ? 195.559 203.346 189.808 1.00 33.45  ? 245 ILE B CB  1 
ATOM   3486 C CG1 . ILE B 1 245 ? 196.283 204.541 189.184 1.00 37.58  ? 245 ILE B CG1 1 
ATOM   3487 C CG2 . ILE B 1 245 ? 196.566 202.325 190.293 1.00 42.05  ? 245 ILE B CG2 1 
ATOM   3488 C CD1 . ILE B 1 245 ? 197.281 205.198 190.108 1.00 47.68  ? 245 ILE B CD1 1 
ATOM   3489 N N   . VAL B 1 246 ? 195.759 201.009 187.543 1.00 39.98  ? 246 VAL B N   1 
ATOM   3490 C CA  . VAL B 1 246 ? 196.397 200.487 186.337 1.00 31.92  ? 246 VAL B CA  1 
ATOM   3491 C C   . VAL B 1 246 ? 195.362 200.278 185.236 1.00 35.03  ? 246 VAL B C   1 
ATOM   3492 O O   . VAL B 1 246 ? 195.606 200.591 184.064 1.00 35.59  ? 246 VAL B O   1 
ATOM   3493 C CB  . VAL B 1 246 ? 197.168 199.193 186.644 1.00 30.54  ? 246 VAL B CB  1 
ATOM   3494 C CG1 . VAL B 1 246 ? 197.731 198.605 185.364 1.00 31.18  ? 246 VAL B CG1 1 
ATOM   3495 C CG2 . VAL B 1 246 ? 198.277 199.477 187.623 1.00 43.55  ? 246 VAL B CG2 1 
ATOM   3496 N N   . LEU B 1 247 ? 194.188 199.752 185.597 1.00 42.12  ? 247 LEU B N   1 
ATOM   3497 C CA  . LEU B 1 247 ? 193.131 199.554 184.613 1.00 39.57  ? 247 LEU B CA  1 
ATOM   3498 C C   . LEU B 1 247 ? 192.640 200.884 184.056 1.00 45.99  ? 247 LEU B C   1 
ATOM   3499 O O   . LEU B 1 247 ? 192.274 200.973 182.883 1.00 55.24  ? 247 LEU B O   1 
ATOM   3500 C CB  . LEU B 1 247 ? 191.978 198.773 185.240 1.00 33.00  ? 247 LEU B CB  1 
ATOM   3501 C CG  . LEU B 1 247 ? 192.087 197.250 185.160 1.00 26.97  ? 247 LEU B CG  1 
ATOM   3502 C CD1 . LEU B 1 247 ? 190.842 196.590 185.725 1.00 33.95  ? 247 LEU B CD1 1 
ATOM   3503 C CD2 . LEU B 1 247 ? 192.326 196.811 183.729 1.00 35.31  ? 247 LEU B CD2 1 
ATOM   3504 N N   . ASN B 1 248 ? 192.632 201.931 184.882 1.00 42.80  ? 248 ASN B N   1 
ATOM   3505 C CA  . ASN B 1 248 ? 192.215 203.246 184.407 1.00 33.20  ? 248 ASN B CA  1 
ATOM   3506 C C   . ASN B 1 248 ? 193.246 203.840 183.456 1.00 46.44  ? 248 ASN B C   1 
ATOM   3507 O O   . ASN B 1 248 ? 192.885 204.463 182.451 1.00 52.91  ? 248 ASN B O   1 
ATOM   3508 C CB  . ASN B 1 248 ? 191.974 204.175 185.596 1.00 39.71  ? 248 ASN B CB  1 
ATOM   3509 C CG  . ASN B 1 248 ? 191.203 205.423 185.216 1.00 58.71  ? 248 ASN B CG  1 
ATOM   3510 O OD1 . ASN B 1 248 ? 191.677 206.248 184.435 1.00 63.33  ? 248 ASN B OD1 1 
ATOM   3511 N ND2 . ASN B 1 248 ? 190.004 205.568 185.770 1.00 62.14  ? 248 ASN B ND2 1 
ATOM   3512 N N   . ILE B 1 249 ? 194.535 203.659 183.757 1.00 41.70  ? 249 ILE B N   1 
ATOM   3513 C CA  . ILE B 1 249 ? 195.566 204.107 182.824 1.00 39.43  ? 249 ILE B CA  1 
ATOM   3514 C C   . ILE B 1 249 ? 195.451 203.354 181.503 1.00 40.31  ? 249 ILE B C   1 
ATOM   3515 O O   . ILE B 1 249 ? 195.564 203.952 180.423 1.00 44.78  ? 249 ILE B O   1 
ATOM   3516 C CB  . ILE B 1 249 ? 196.963 203.947 183.451 1.00 38.36  ? 249 ILE B CB  1 
ATOM   3517 C CG1 . ILE B 1 249 ? 197.149 204.950 184.591 1.00 45.62  ? 249 ILE B CG1 1 
ATOM   3518 C CG2 . ILE B 1 249 ? 198.043 204.140 182.399 1.00 40.61  ? 249 ILE B CG2 1 
ATOM   3519 C CD1 . ILE B 1 249 ? 198.573 205.050 185.095 1.00 46.65  ? 249 ILE B CD1 1 
ATOM   3520 N N   . THR B 1 250 ? 195.212 202.043 181.563 1.00 40.05  ? 250 THR B N   1 
ATOM   3521 C CA  . THR B 1 250 ? 194.975 201.252 180.362 1.00 39.84  ? 250 THR B CA  1 
ATOM   3522 C C   . THR B 1 250 ? 193.746 201.717 179.591 1.00 46.76  ? 250 THR B C   1 
ATOM   3523 O O   . THR B 1 250 ? 193.790 201.778 178.360 1.00 46.13  ? 250 THR B O   1 
ATOM   3524 C CB  . THR B 1 250 ? 194.830 199.772 180.733 1.00 43.09  ? 250 THR B CB  1 
ATOM   3525 O OG1 . THR B 1 250 ? 196.105 199.250 181.124 1.00 52.79  ? 250 THR B OG1 1 
ATOM   3526 C CG2 . THR B 1 250 ? 194.300 198.964 179.559 1.00 45.12  ? 250 THR B CG2 1 
ATOM   3527 N N   . LEU B 1 251 ? 192.659 202.051 180.289 1.00 49.67  ? 251 LEU B N   1 
ATOM   3528 C CA  . LEU B 1 251 ? 191.461 202.590 179.656 1.00 43.70  ? 251 LEU B CA  1 
ATOM   3529 C C   . LEU B 1 251 ? 191.748 203.899 178.936 1.00 42.39  ? 251 LEU B C   1 
ATOM   3530 O O   . LEU B 1 251 ? 191.302 204.096 177.800 1.00 53.92  ? 251 LEU B O   1 
ATOM   3531 C CB  . LEU B 1 251 ? 190.373 202.798 180.710 1.00 42.25  ? 251 LEU B CB  1 
ATOM   3532 C CG  . LEU B 1 251 ? 188.936 202.373 180.412 1.00 36.37  ? 251 LEU B CG  1 
ATOM   3533 C CD1 . LEU B 1 251 ? 188.897 201.107 179.587 1.00 44.22  ? 251 LEU B CD1 1 
ATOM   3534 C CD2 . LEU B 1 251 ? 188.187 202.179 181.719 1.00 41.81  ? 251 LEU B CD2 1 
ATOM   3535 N N   . VAL B 1 252 ? 192.486 204.803 179.582 1.00 33.39  ? 252 VAL B N   1 
ATOM   3536 C CA  . VAL B 1 252 ? 192.832 206.071 178.948 1.00 33.83  ? 252 VAL B CA  1 
ATOM   3537 C C   . VAL B 1 252 ? 193.682 205.833 177.706 1.00 46.80  ? 252 VAL B C   1 
ATOM   3538 O O   . VAL B 1 252 ? 193.449 206.439 176.651 1.00 51.81  ? 252 VAL B O   1 
ATOM   3539 C CB  . VAL B 1 252 ? 193.541 206.996 179.953 1.00 30.29  ? 252 VAL B CB  1 
ATOM   3540 C CG1 . VAL B 1 252 ? 194.060 208.242 179.254 1.00 31.03  ? 252 VAL B CG1 1 
ATOM   3541 C CG2 . VAL B 1 252 ? 192.596 207.373 181.081 1.00 40.11  ? 252 VAL B CG2 1 
ATOM   3542 N N   . LEU B 1 253 ? 194.676 204.946 177.806 1.00 55.51  ? 253 LEU B N   1 
ATOM   3543 C CA  . LEU B 1 253 ? 195.532 204.669 176.656 1.00 46.76  ? 253 LEU B CA  1 
ATOM   3544 C C   . LEU B 1 253 ? 194.743 204.040 175.514 1.00 49.30  ? 253 LEU B C   1 
ATOM   3545 O O   . LEU B 1 253 ? 194.955 204.379 174.344 1.00 55.54  ? 253 LEU B O   1 
ATOM   3546 C CB  . LEU B 1 253 ? 196.694 203.767 177.070 1.00 41.00  ? 253 LEU B CB  1 
ATOM   3547 C CG  . LEU B 1 253 ? 197.914 204.508 177.617 1.00 47.76  ? 253 LEU B CG  1 
ATOM   3548 C CD1 . LEU B 1 253 ? 198.856 203.552 178.330 1.00 54.31  ? 253 LEU B CD1 1 
ATOM   3549 C CD2 . LEU B 1 253 ? 198.630 205.244 176.498 1.00 47.28  ? 253 LEU B CD2 1 
ATOM   3550 N N   . ALA B 1 254 ? 193.831 203.118 175.832 1.00 48.42  ? 254 ALA B N   1 
ATOM   3551 C CA  . ALA B 1 254 ? 193.007 202.500 174.799 1.00 53.05  ? 254 ALA B CA  1 
ATOM   3552 C C   . ALA B 1 254 ? 192.091 203.520 174.139 1.00 50.31  ? 254 ALA B C   1 
ATOM   3553 O O   . ALA B 1 254 ? 191.907 203.497 172.917 1.00 56.32  ? 254 ALA B O   1 
ATOM   3554 C CB  . ALA B 1 254 ? 192.194 201.351 175.394 1.00 49.13  ? 254 ALA B CB  1 
ATOM   3555 N N   . ALA B 1 255 ? 191.505 204.422 174.929 1.00 44.86  ? 255 ALA B N   1 
ATOM   3556 C CA  . ALA B 1 255 ? 190.657 205.463 174.358 1.00 49.56  ? 255 ALA B CA  1 
ATOM   3557 C C   . ALA B 1 255 ? 191.455 206.376 173.439 1.00 52.42  ? 255 ALA B C   1 
ATOM   3558 O O   . ALA B 1 255 ? 190.972 206.772 172.372 1.00 57.39  ? 255 ALA B O   1 
ATOM   3559 C CB  . ALA B 1 255 ? 189.991 206.269 175.473 1.00 50.72  ? 255 ALA B CB  1 
ATOM   3560 N N   . VAL B 1 256 ? 192.680 206.724 173.837 1.00 44.37  ? 256 VAL B N   1 
ATOM   3561 C CA  . VAL B 1 256 ? 193.519 207.566 172.991 1.00 47.98  ? 256 VAL B CA  1 
ATOM   3562 C C   . VAL B 1 256 ? 193.889 206.839 171.702 1.00 54.88  ? 256 VAL B C   1 
ATOM   3563 O O   . VAL B 1 256 ? 193.859 207.425 170.613 1.00 56.08  ? 256 VAL B O   1 
ATOM   3564 C CB  . VAL B 1 256 ? 194.769 208.023 173.765 1.00 44.85  ? 256 VAL B CB  1 
ATOM   3565 C CG1 . VAL B 1 256 ? 195.748 208.721 172.834 1.00 49.16  ? 256 VAL B CG1 1 
ATOM   3566 C CG2 . VAL B 1 256 ? 194.375 208.947 174.904 1.00 47.72  ? 256 VAL B CG2 1 
ATOM   3567 N N   . PHE B 1 257 ? 194.230 205.552 171.796 1.00 57.84  ? 257 PHE B N   1 
ATOM   3568 C CA  . PHE B 1 257 ? 194.792 204.816 170.667 1.00 55.74  ? 257 PHE B CA  1 
ATOM   3569 C C   . PHE B 1 257 ? 193.756 203.965 169.938 1.00 59.80  ? 257 PHE B C   1 
ATOM   3570 O O   . PHE B 1 257 ? 193.538 204.145 168.737 1.00 67.49  ? 257 PHE B O   1 
ATOM   3571 C CB  . PHE B 1 257 ? 195.954 203.938 171.151 1.00 50.93  ? 257 PHE B CB  1 
ATOM   3572 C CG  . PHE B 1 257 ? 197.211 204.706 171.437 1.00 58.64  ? 257 PHE B CG  1 
ATOM   3573 C CD1 . PHE B 1 257 ? 197.641 205.702 170.577 1.00 59.26  ? 257 PHE B CD1 1 
ATOM   3574 C CD2 . PHE B 1 257 ? 197.961 204.436 172.569 1.00 61.10  ? 257 PHE B CD2 1 
ATOM   3575 C CE1 . PHE B 1 257 ? 198.798 206.412 170.838 1.00 57.98  ? 257 PHE B CE1 1 
ATOM   3576 C CE2 . PHE B 1 257 ? 199.119 205.142 172.836 1.00 60.49  ? 257 PHE B CE2 1 
ATOM   3577 C CZ  . PHE B 1 257 ? 199.537 206.131 171.969 1.00 58.66  ? 257 PHE B CZ  1 
ATOM   3578 N N   . LYS B 1 258 ? 193.113 203.035 170.641 1.00 64.52  ? 258 LYS B N   1 
ATOM   3579 C CA  . LYS B 1 258 ? 192.215 202.064 170.012 1.00 67.99  ? 258 LYS B CA  1 
ATOM   3580 C C   . LYS B 1 258 ? 190.773 202.521 170.215 1.00 72.83  ? 258 LYS B C   1 
ATOM   3581 O O   . LYS B 1 258 ? 190.117 202.162 171.193 1.00 79.29  ? 258 LYS B O   1 
ATOM   3582 C CB  . LYS B 1 258 ? 192.445 200.667 170.575 1.00 65.89  ? 258 LYS B CB  1 
ATOM   3583 C CG  . LYS B 1 258 ? 191.609 199.592 169.901 1.00 70.85  ? 258 LYS B CG  1 
ATOM   3584 C CD  . LYS B 1 258 ? 192.228 198.216 170.062 1.00 76.77  ? 258 LYS B CD  1 
ATOM   3585 C CE  . LYS B 1 258 ? 191.495 197.186 169.217 1.00 76.94  ? 258 LYS B CE  1 
ATOM   3586 N NZ  . LYS B 1 258 ? 192.187 195.868 169.218 1.00 74.79  ? 258 LYS B NZ  1 
ATOM   3587 N N   . LEU B 1 259 ? 190.279 203.318 169.272 1.00 80.30  ? 259 LEU B N   1 
ATOM   3588 C CA  . LEU B 1 259 ? 188.886 203.738 169.274 1.00 80.81  ? 259 LEU B CA  1 
ATOM   3589 C C   . LEU B 1 259 ? 188.496 204.116 167.853 1.00 81.57  ? 259 LEU B C   1 
ATOM   3590 O O   . LEU B 1 259 ? 189.332 204.572 167.068 1.00 80.41  ? 259 LEU B O   1 
ATOM   3591 C CB  . LEU B 1 259 ? 188.648 204.911 170.232 1.00 79.12  ? 259 LEU B CB  1 
ATOM   3592 C CG  . LEU B 1 259 ? 187.191 205.208 170.593 1.00 80.71  ? 259 LEU B CG  1 
ATOM   3593 C CD1 . LEU B 1 259 ? 186.492 203.948 171.079 1.00 74.73  ? 259 LEU B CD1 1 
ATOM   3594 C CD2 . LEU B 1 259 ? 187.109 206.306 171.641 1.00 79.59  ? 259 LEU B CD2 1 
ATOM   3595 N N   . GLU B 1 260 ? 187.220 203.922 167.534 1.00 101.12 ? 260 GLU B N   1 
ATOM   3596 C CA  . GLU B 1 260 ? 186.687 204.201 166.207 1.00 100.95 ? 260 GLU B CA  1 
ATOM   3597 C C   . GLU B 1 260 ? 185.885 205.494 166.257 1.00 103.31 ? 260 GLU B C   1 
ATOM   3598 O O   . GLU B 1 260 ? 184.947 205.616 167.052 1.00 101.50 ? 260 GLU B O   1 
ATOM   3599 C CB  . GLU B 1 260 ? 185.815 203.047 165.712 1.00 101.79 ? 260 GLU B CB  1 
ATOM   3600 C CG  . GLU B 1 260 ? 186.549 201.723 165.577 1.00 100.58 ? 260 GLU B CG  1 
ATOM   3601 C CD  . GLU B 1 260 ? 186.354 200.822 166.781 1.00 103.28 ? 260 GLU B CD  1 
ATOM   3602 O OE1 . GLU B 1 260 ? 186.386 201.334 167.920 1.00 103.15 ? 260 GLU B OE1 1 
ATOM   3603 O OE2 . GLU B 1 260 ? 186.168 199.602 166.589 1.00 104.04 ? 260 GLU B OE2 1 
ATOM   3604 N N   . THR B 1 261 ? 186.256 206.453 165.411 1.00 118.12 ? 261 THR B N   1 
ATOM   3605 C CA  . THR B 1 261 ? 185.533 207.713 165.310 1.00 117.49 ? 261 THR B CA  1 
ATOM   3606 C C   . THR B 1 261 ? 184.354 207.643 164.351 1.00 117.84 ? 261 THR B C   1 
ATOM   3607 O O   . THR B 1 261 ? 183.567 208.594 164.290 1.00 119.85 ? 261 THR B O   1 
ATOM   3608 C CB  . THR B 1 261 ? 186.478 208.836 164.868 1.00 118.75 ? 261 THR B CB  1 
ATOM   3609 O OG1 . THR B 1 261 ? 186.959 208.565 163.545 1.00 118.40 ? 261 THR B OG1 1 
ATOM   3610 C CG2 . THR B 1 261 ? 187.659 208.944 165.820 1.00 117.90 ? 261 THR B CG2 1 
ATOM   3611 N N   . ASP B 1 262 ? 184.213 206.546 163.603 1.00 118.74 ? 262 ASP B N   1 
ATOM   3612 C CA  . ASP B 1 262 ? 183.073 206.406 162.705 1.00 120.43 ? 262 ASP B CA  1 
ATOM   3613 C C   . ASP B 1 262 ? 181.786 206.134 163.472 1.00 122.06 ? 262 ASP B C   1 
ATOM   3614 O O   . ASP B 1 262 ? 180.702 206.511 163.015 1.00 121.97 ? 262 ASP B O   1 
ATOM   3615 C CB  . ASP B 1 262 ? 183.333 205.287 161.697 1.00 119.25 ? 262 ASP B CB  1 
ATOM   3616 C CG  . ASP B 1 262 ? 184.678 205.421 161.013 1.00 119.70 ? 262 ASP B CG  1 
ATOM   3617 O OD1 . ASP B 1 262 ? 184.889 206.426 160.303 1.00 120.16 ? 262 ASP B OD1 1 
ATOM   3618 O OD2 . ASP B 1 262 ? 185.527 204.521 161.188 1.00 120.64 ? 262 ASP B OD2 1 
ATOM   3619 N N   . ARG B 1 263 ? 181.885 205.489 164.630 1.00 123.42 ? 263 ARG B N   1 
ATOM   3620 C CA  . ARG B 1 263 ? 180.728 205.142 165.439 1.00 122.88 ? 263 ARG B CA  1 
ATOM   3621 C C   . ARG B 1 263 ? 180.640 206.076 166.639 1.00 120.58 ? 263 ARG B C   1 
ATOM   3622 O O   . ARG B 1 263 ? 181.657 206.535 167.166 1.00 121.69 ? 263 ARG B O   1 
ATOM   3623 C CB  . ARG B 1 263 ? 180.805 203.685 165.907 1.00 121.65 ? 263 ARG B CB  1 
ATOM   3624 C CG  . ARG B 1 263 ? 181.424 202.747 164.880 1.00 120.15 ? 263 ARG B CG  1 
ATOM   3625 C CD  . ARG B 1 263 ? 181.679 201.362 165.463 1.00 121.01 ? 263 ARG B CD  1 
ATOM   3626 N NE  . ARG B 1 263 ? 180.447 200.616 165.704 1.00 124.89 ? 263 ARG B NE  1 
ATOM   3627 C CZ  . ARG B 1 263 ? 179.570 200.275 164.768 1.00 123.78 ? 263 ARG B CZ  1 
ATOM   3628 N NH1 . ARG B 1 263 ? 179.792 200.514 163.486 1.00 122.11 ? 263 ARG B NH1 1 
ATOM   3629 N NH2 . ARG B 1 263 ? 178.447 199.659 165.127 1.00 123.76 ? 263 ARG B NH2 1 
ATOM   3630 N N   . SER B 1 264 ? 179.411 206.356 167.065 1.00 100.82 ? 264 SER B N   1 
ATOM   3631 C CA  . SER B 1 264 ? 179.170 207.303 168.149 1.00 99.22  ? 264 SER B CA  1 
ATOM   3632 C C   . SER B 1 264 ? 179.440 206.619 169.483 1.00 102.56 ? 264 SER B C   1 
ATOM   3633 O O   . SER B 1 264 ? 178.741 205.672 169.858 1.00 104.16 ? 264 SER B O   1 
ATOM   3634 C CB  . SER B 1 264 ? 177.741 207.835 168.085 1.00 98.58  ? 264 SER B CB  1 
ATOM   3635 O OG  . SER B 1 264 ? 176.814 206.854 168.514 1.00 97.19  ? 264 SER B OG  1 
ATOM   3636 N N   . ILE B 1 265 ? 180.459 207.101 170.204 1.00 93.98  ? 265 ILE B N   1 
ATOM   3637 C CA  . ILE B 1 265 ? 180.782 206.569 171.527 1.00 92.59  ? 265 ILE B CA  1 
ATOM   3638 C C   . ILE B 1 265 ? 179.888 207.128 172.619 1.00 87.68  ? 265 ILE B C   1 
ATOM   3639 O O   . ILE B 1 265 ? 180.012 206.712 173.779 1.00 91.89  ? 265 ILE B O   1 
ATOM   3640 C CB  . ILE B 1 265 ? 182.249 206.858 171.900 1.00 94.97  ? 265 ILE B CB  1 
ATOM   3641 C CG1 . ILE B 1 265 ? 182.431 208.342 172.224 1.00 89.91  ? 265 ILE B CG1 1 
ATOM   3642 C CG2 . ILE B 1 265 ? 183.177 206.439 170.772 1.00 97.32  ? 265 ILE B CG2 1 
ATOM   3643 C CD1 . ILE B 1 265 ? 183.791 208.682 172.790 1.00 92.11  ? 265 ILE B CD1 1 
ATOM   3644 N N   . TRP B 1 266 ? 178.998 208.062 172.288 1.00 83.91  ? 266 TRP B N   1 
ATOM   3645 C CA  . TRP B 1 266 ? 178.190 208.714 173.314 1.00 84.58  ? 266 TRP B CA  1 
ATOM   3646 C C   . TRP B 1 266 ? 177.273 207.774 174.088 1.00 83.68  ? 266 TRP B C   1 
ATOM   3647 O O   . TRP B 1 266 ? 177.171 207.943 175.316 1.00 90.29  ? 266 TRP B O   1 
ATOM   3648 C CB  . TRP B 1 266 ? 177.393 209.864 172.689 1.00 88.22  ? 266 TRP B CB  1 
ATOM   3649 C CG  . TRP B 1 266 ? 178.156 211.144 172.687 1.00 90.94  ? 266 TRP B CG  1 
ATOM   3650 C CD1 . TRP B 1 266 ? 178.478 211.909 171.605 1.00 91.92  ? 266 TRP B CD1 1 
ATOM   3651 C CD2 . TRP B 1 266 ? 178.713 211.806 173.828 1.00 88.69  ? 266 TRP B CD2 1 
ATOM   3652 N NE1 . TRP B 1 266 ? 179.196 213.011 172.003 1.00 93.38  ? 266 TRP B NE1 1 
ATOM   3653 C CE2 . TRP B 1 266 ? 179.352 212.970 173.364 1.00 89.50  ? 266 TRP B CE2 1 
ATOM   3654 C CE3 . TRP B 1 266 ? 178.727 211.530 175.198 1.00 88.65  ? 266 TRP B CE3 1 
ATOM   3655 C CZ2 . TRP B 1 266 ? 179.999 213.854 174.220 1.00 88.48  ? 266 TRP B CZ2 1 
ATOM   3656 C CZ3 . TRP B 1 266 ? 179.370 212.407 176.045 1.00 89.22  ? 266 TRP B CZ3 1 
ATOM   3657 C CH2 . TRP B 1 266 ? 179.997 213.554 175.554 1.00 89.65  ? 266 TRP B CH2 1 
ATOM   3658 N N   . PRO B 1 267 ? 176.560 206.821 173.472 1.00 71.08  ? 267 PRO B N   1 
ATOM   3659 C CA  . PRO B 1 267 ? 175.766 205.893 174.297 1.00 70.53  ? 267 PRO B CA  1 
ATOM   3660 C C   . PRO B 1 267 ? 176.599 205.147 175.323 1.00 79.19  ? 267 PRO B C   1 
ATOM   3661 O O   . PRO B 1 267 ? 176.160 204.978 176.467 1.00 78.83  ? 267 PRO B O   1 
ATOM   3662 C CB  . PRO B 1 267 ? 175.151 204.945 173.259 1.00 70.65  ? 267 PRO B CB  1 
ATOM   3663 C CG  . PRO B 1 267 ? 175.085 205.753 172.019 1.00 80.96  ? 267 PRO B CG  1 
ATOM   3664 C CD  . PRO B 1 267 ? 176.317 206.607 172.034 1.00 79.34  ? 267 PRO B CD  1 
ATOM   3665 N N   . LEU B 1 268 ? 177.810 204.725 174.952 1.00 77.59  ? 268 LEU B N   1 
ATOM   3666 C CA  . LEU B 1 268 ? 178.682 204.032 175.895 1.00 68.35  ? 268 LEU B CA  1 
ATOM   3667 C C   . LEU B 1 268 ? 179.049 204.934 177.067 1.00 63.09  ? 268 LEU B C   1 
ATOM   3668 O O   . LEU B 1 268 ? 179.004 204.516 178.232 1.00 65.01  ? 268 LEU B O   1 
ATOM   3669 C CB  . LEU B 1 268 ? 179.940 203.550 175.174 1.00 62.44  ? 268 LEU B CB  1 
ATOM   3670 C CG  . LEU B 1 268 ? 180.927 202.690 175.962 1.00 64.09  ? 268 LEU B CG  1 
ATOM   3671 C CD1 . LEU B 1 268 ? 180.623 201.220 175.751 1.00 65.70  ? 268 LEU B CD1 1 
ATOM   3672 C CD2 . LEU B 1 268 ? 182.357 203.011 175.557 1.00 66.65  ? 268 LEU B CD2 1 
ATOM   3673 N N   . ILE B 1 269 ? 179.412 206.184 176.772 1.00 54.94  ? 269 ILE B N   1 
ATOM   3674 C CA  . ILE B 1 269 ? 179.788 207.121 177.825 1.00 50.92  ? 269 ILE B CA  1 
ATOM   3675 C C   . ILE B 1 269 ? 178.608 207.378 178.751 1.00 49.39  ? 269 ILE B C   1 
ATOM   3676 O O   . ILE B 1 269 ? 178.756 207.393 179.978 1.00 60.23  ? 269 ILE B O   1 
ATOM   3677 C CB  . ILE B 1 269 ? 180.325 208.427 177.210 1.00 54.26  ? 269 ILE B CB  1 
ATOM   3678 C CG1 . ILE B 1 269 ? 181.803 208.275 176.845 1.00 55.81  ? 269 ILE B CG1 1 
ATOM   3679 C CG2 . ILE B 1 269 ? 180.134 209.594 178.165 1.00 52.44  ? 269 ILE B CG2 1 
ATOM   3680 C CD1 . ILE B 1 269 ? 182.678 207.853 178.004 1.00 54.57  ? 269 ILE B CD1 1 
ATOM   3681 N N   . ARG B 1 270 ? 177.418 207.572 178.181 1.00 64.36  ? 270 ARG B N   1 
ATOM   3682 C CA  . ARG B 1 270 ? 176.242 207.841 179.002 1.00 70.21  ? 270 ARG B CA  1 
ATOM   3683 C C   . ARG B 1 270 ? 175.893 206.643 179.876 1.00 70.30  ? 270 ARG B C   1 
ATOM   3684 O O   . ARG B 1 270 ? 175.491 206.803 181.034 1.00 79.44  ? 270 ARG B O   1 
ATOM   3685 C CB  . ARG B 1 270 ? 175.058 208.230 178.117 1.00 75.36  ? 270 ARG B CB  1 
ATOM   3686 C CG  . ARG B 1 270 ? 175.185 209.600 177.471 1.00 71.87  ? 270 ARG B CG  1 
ATOM   3687 C CD  . ARG B 1 270 ? 173.956 209.928 176.641 1.00 69.64  ? 270 ARG B CD  1 
ATOM   3688 N NE  . ARG B 1 270 ? 174.251 210.860 175.560 1.00 77.91  ? 270 ARG B NE  1 
ATOM   3689 C CZ  . ARG B 1 270 ? 174.115 210.578 174.272 1.00 82.06  ? 270 ARG B CZ  1 
ATOM   3690 N NH1 . ARG B 1 270 ? 173.687 209.394 173.866 1.00 79.97  ? 270 ARG B NH1 1 
ATOM   3691 N NH2 . ARG B 1 270 ? 174.414 211.507 173.369 1.00 82.17  ? 270 ARG B NH2 1 
ATOM   3692 N N   . ILE B 1 271 ? 176.031 205.429 179.336 1.00 48.62  ? 271 ILE B N   1 
ATOM   3693 C CA  . ILE B 1 271 ? 175.717 204.242 180.126 1.00 51.82  ? 271 ILE B CA  1 
ATOM   3694 C C   . ILE B 1 271 ? 176.713 204.073 181.269 1.00 54.73  ? 271 ILE B C   1 
ATOM   3695 O O   . ILE B 1 271 ? 176.323 203.793 182.409 1.00 53.63  ? 271 ILE B O   1 
ATOM   3696 C CB  . ILE B 1 271 ? 175.664 202.991 179.230 1.00 56.08  ? 271 ILE B CB  1 
ATOM   3697 C CG1 . ILE B 1 271 ? 174.455 203.046 178.295 1.00 60.11  ? 271 ILE B CG1 1 
ATOM   3698 C CG2 . ILE B 1 271 ? 175.604 201.734 180.075 1.00 56.10  ? 271 ILE B CG2 1 
ATOM   3699 C CD1 . ILE B 1 271 ? 174.643 202.271 177.006 1.00 57.70  ? 271 ILE B CD1 1 
ATOM   3700 N N   . TYR B 1 272 ? 178.007 204.249 180.995 1.00 51.91  ? 272 TYR B N   1 
ATOM   3701 C CA  . TYR B 1 272 ? 179.013 204.018 182.027 1.00 45.57  ? 272 TYR B CA  1 
ATOM   3702 C C   . TYR B 1 272 ? 179.182 205.195 182.982 1.00 48.34  ? 272 TYR B C   1 
ATOM   3703 O O   . TYR B 1 272 ? 179.845 205.042 184.018 1.00 54.43  ? 272 TYR B O   1 
ATOM   3704 C CB  . TYR B 1 272 ? 180.360 203.679 181.383 1.00 43.40  ? 272 TYR B CB  1 
ATOM   3705 C CG  . TYR B 1 272 ? 180.438 202.263 180.855 1.00 42.76  ? 272 TYR B CG  1 
ATOM   3706 C CD1 . TYR B 1 272 ? 179.873 201.924 179.635 1.00 42.85  ? 272 TYR B CD1 1 
ATOM   3707 C CD2 . TYR B 1 272 ? 181.069 201.265 181.583 1.00 51.13  ? 272 TYR B CD2 1 
ATOM   3708 C CE1 . TYR B 1 272 ? 179.940 200.633 179.152 1.00 38.45  ? 272 TYR B CE1 1 
ATOM   3709 C CE2 . TYR B 1 272 ? 181.140 199.971 181.108 1.00 49.40  ? 272 TYR B CE2 1 
ATOM   3710 C CZ  . TYR B 1 272 ? 180.573 199.661 179.893 1.00 41.97  ? 272 TYR B CZ  1 
ATOM   3711 O OH  . TYR B 1 272 ? 180.642 198.372 179.416 1.00 52.67  ? 272 TYR B OH  1 
ATOM   3712 N N   . ARG B 1 273 ? 178.601 206.355 182.665 1.00 44.33  ? 273 ARG B N   1 
ATOM   3713 C CA  . ARG B 1 273 ? 178.723 207.510 183.546 1.00 39.71  ? 273 ARG B CA  1 
ATOM   3714 C C   . ARG B 1 273 ? 178.073 207.250 184.898 1.00 44.39  ? 273 ARG B C   1 
ATOM   3715 O O   . ARG B 1 273 ? 178.610 207.649 185.936 1.00 53.75  ? 273 ARG B O   1 
ATOM   3716 C CB  . ARG B 1 273 ? 178.108 208.739 182.878 1.00 39.61  ? 273 ARG B CB  1 
ATOM   3717 C CG  . ARG B 1 273 ? 178.129 209.994 183.728 1.00 44.06  ? 273 ARG B CG  1 
ATOM   3718 C CD  . ARG B 1 273 ? 177.608 211.188 182.947 1.00 45.96  ? 273 ARG B CD  1 
ATOM   3719 N NE  . ARG B 1 273 ? 176.270 210.952 182.419 1.00 38.17  ? 273 ARG B NE  1 
ATOM   3720 C CZ  . ARG B 1 273 ? 175.712 211.661 181.448 1.00 47.54  ? 273 ARG B CZ  1 
ATOM   3721 N NH1 . ARG B 1 273 ? 176.352 212.663 180.869 1.00 51.71  ? 273 ARG B NH1 1 
ATOM   3722 N NH2 . ARG B 1 273 ? 174.481 211.356 181.048 1.00 53.36  ? 273 ARG B NH2 1 
ATOM   3723 N N   . GLY B 1 274 ? 176.915 206.587 184.908 1.00 32.15  ? 274 GLY B N   1 
ATOM   3724 C CA  . GLY B 1 274 ? 176.266 206.280 186.173 1.00 43.79  ? 274 GLY B CA  1 
ATOM   3725 C C   . GLY B 1 274 ? 177.102 205.370 187.052 1.00 41.02  ? 274 GLY B C   1 
ATOM   3726 O O   . GLY B 1 274 ? 177.230 205.598 188.258 1.00 46.68  ? 274 GLY B O   1 
ATOM   3727 N N   . GLY B 1 275 ? 177.687 204.328 186.459 1.00 33.63  ? 275 GLY B N   1 
ATOM   3728 C CA  . GLY B 1 275 ? 178.568 203.459 187.219 1.00 32.20  ? 275 GLY B CA  1 
ATOM   3729 C C   . GLY B 1 275 ? 179.783 204.190 187.756 1.00 29.30  ? 275 GLY B C   1 
ATOM   3730 O O   . GLY B 1 275 ? 180.171 204.002 188.913 1.00 38.89  ? 275 GLY B O   1 
ATOM   3731 N N   . PHE B 1 276 ? 180.398 205.039 186.928 1.00 21.27  ? 276 PHE B N   1 
ATOM   3732 C CA  . PHE B 1 276 ? 181.557 205.796 187.393 1.00 15.36  ? 276 PHE B CA  1 
ATOM   3733 C C   . PHE B 1 276 ? 181.180 206.731 188.534 1.00 26.14  ? 276 PHE B C   1 
ATOM   3734 O O   . PHE B 1 276 ? 181.939 206.886 189.500 1.00 48.16  ? 276 PHE B O   1 
ATOM   3735 C CB  . PHE B 1 276 ? 182.177 206.584 186.243 1.00 26.55  ? 276 PHE B CB  1 
ATOM   3736 C CG  . PHE B 1 276 ? 183.259 207.528 186.678 1.00 24.07  ? 276 PHE B CG  1 
ATOM   3737 C CD1 . PHE B 1 276 ? 184.383 207.056 187.333 1.00 22.88  ? 276 PHE B CD1 1 
ATOM   3738 C CD2 . PHE B 1 276 ? 183.152 208.886 186.438 1.00 29.47  ? 276 PHE B CD2 1 
ATOM   3739 C CE1 . PHE B 1 276 ? 185.381 207.919 187.738 1.00 25.12  ? 276 PHE B CE1 1 
ATOM   3740 C CE2 . PHE B 1 276 ? 184.147 209.755 186.841 1.00 32.82  ? 276 PHE B CE2 1 
ATOM   3741 C CZ  . PHE B 1 276 ? 185.263 209.270 187.491 1.00 27.65  ? 276 PHE B CZ  1 
ATOM   3742 N N   . LEU B 1 277 ? 180.012 207.369 188.439 1.00 35.42  ? 277 LEU B N   1 
ATOM   3743 C CA  . LEU B 1 277 ? 179.557 208.246 189.511 1.00 39.13  ? 277 LEU B CA  1 
ATOM   3744 C C   . LEU B 1 277 ? 179.302 207.463 190.790 1.00 38.41  ? 277 LEU B C   1 
ATOM   3745 O O   . LEU B 1 277 ? 179.599 207.946 191.885 1.00 27.68  ? 277 LEU B O   1 
ATOM   3746 C CB  . LEU B 1 277 ? 178.301 208.999 189.079 1.00 14.61  ? 277 LEU B CB  1 
ATOM   3747 C CG  . LEU B 1 277 ? 178.519 210.060 188.001 1.00 22.09  ? 277 LEU B CG  1 
ATOM   3748 C CD1 . LEU B 1 277 ? 177.199 210.448 187.365 1.00 38.88  ? 277 LEU B CD1 1 
ATOM   3749 C CD2 . LEU B 1 277 ? 179.225 211.275 188.570 1.00 30.71  ? 277 LEU B CD2 1 
ATOM   3750 N N   . LEU B 1 278 ? 178.748 206.253 190.674 1.00 40.24  ? 278 LEU B N   1 
ATOM   3751 C CA  . LEU B 1 278 ? 178.554 205.421 191.858 1.00 28.35  ? 278 LEU B CA  1 
ATOM   3752 C C   . LEU B 1 278 ? 179.888 205.052 192.499 1.00 24.98  ? 278 LEU B C   1 
ATOM   3753 O O   . LEU B 1 278 ? 180.020 205.066 193.730 1.00 35.75  ? 278 LEU B O   1 
ATOM   3754 C CB  . LEU B 1 278 ? 177.765 204.164 191.494 1.00 35.87  ? 278 LEU B CB  1 
ATOM   3755 C CG  . LEU B 1 278 ? 177.359 203.262 192.660 1.00 30.48  ? 278 LEU B CG  1 
ATOM   3756 C CD1 . LEU B 1 278 ? 176.410 203.991 193.595 1.00 29.12  ? 278 LEU B CD1 1 
ATOM   3757 C CD2 . LEU B 1 278 ? 176.730 201.979 192.148 1.00 35.03  ? 278 LEU B CD2 1 
ATOM   3758 N N   . ILE B 1 279 ? 180.888 204.714 191.680 1.00 25.14  ? 279 ILE B N   1 
ATOM   3759 C CA  . ILE B 1 279 ? 182.209 204.381 192.218 1.00 22.43  ? 279 ILE B CA  1 
ATOM   3760 C C   . ILE B 1 279 ? 182.798 205.582 192.947 1.00 27.26  ? 279 ILE B C   1 
ATOM   3761 O O   . ILE B 1 279 ? 183.333 205.464 194.060 1.00 51.00  ? 279 ILE B O   1 
ATOM   3762 C CB  . ILE B 1 279 ? 183.152 203.898 191.100 1.00 32.38  ? 279 ILE B CB  1 
ATOM   3763 C CG1 . ILE B 1 279 ? 182.543 202.737 190.312 1.00 35.80  ? 279 ILE B CG1 1 
ATOM   3764 C CG2 . ILE B 1 279 ? 184.498 203.496 191.679 1.00 30.07  ? 279 ILE B CG2 1 
ATOM   3765 C CD1 . ILE B 1 279 ? 181.790 201.746 191.147 1.00 30.89  ? 279 ILE B CD1 1 
ATOM   3766 N N   . GLU B 1 280 ? 182.715 206.758 192.319 1.00 21.06  ? 280 GLU B N   1 
ATOM   3767 C CA  . GLU B 1 280 ? 183.236 207.970 192.938 1.00 21.23  ? 280 GLU B CA  1 
ATOM   3768 C C   . GLU B 1 280 ? 182.504 208.281 194.235 1.00 30.44  ? 280 GLU B C   1 
ATOM   3769 O O   . GLU B 1 280 ? 183.121 208.701 195.220 1.00 30.49  ? 280 GLU B O   1 
ATOM   3770 C CB  . GLU B 1 280 ? 183.125 209.141 191.965 1.00 20.12  ? 280 GLU B CB  1 
ATOM   3771 C CG  . GLU B 1 280 ? 183.176 210.506 192.625 1.00 30.99  ? 280 GLU B CG  1 
ATOM   3772 C CD  . GLU B 1 280 ? 183.698 211.572 191.693 1.00 42.24  ? 280 GLU B CD  1 
ATOM   3773 O OE1 . GLU B 1 280 ? 183.225 211.625 190.540 1.00 42.23  ? 280 GLU B OE1 1 
ATOM   3774 O OE2 . GLU B 1 280 ? 184.580 212.353 192.108 1.00 48.35  ? 280 GLU B OE2 1 
ATOM   3775 N N   . PHE B 1 281 ? 181.185 208.081 194.253 1.00 30.84  ? 281 PHE B N   1 
ATOM   3776 C CA  . PHE B 1 281 ? 180.414 208.321 195.465 1.00 28.67  ? 281 PHE B CA  1 
ATOM   3777 C C   . PHE B 1 281 ? 180.833 207.381 196.585 1.00 39.50  ? 281 PHE B C   1 
ATOM   3778 O O   . PHE B 1 281 ? 180.959 207.805 197.736 1.00 46.12  ? 281 PHE B O   1 
ATOM   3779 C CB  . PHE B 1 281 ? 178.922 208.175 195.181 1.00 25.56  ? 281 PHE B CB  1 
ATOM   3780 C CG  . PHE B 1 281 ? 178.064 208.337 196.397 1.00 29.74  ? 281 PHE B CG  1 
ATOM   3781 C CD1 . PHE B 1 281 ? 178.230 209.425 197.233 1.00 36.20  ? 281 PHE B CD1 1 
ATOM   3782 C CD2 . PHE B 1 281 ? 177.099 207.397 196.711 1.00 32.15  ? 281 PHE B CD2 1 
ATOM   3783 C CE1 . PHE B 1 281 ? 177.452 209.575 198.356 1.00 29.79  ? 281 PHE B CE1 1 
ATOM   3784 C CE2 . PHE B 1 281 ? 176.312 207.545 197.834 1.00 39.33  ? 281 PHE B CE2 1 
ATOM   3785 C CZ  . PHE B 1 281 ? 176.488 208.635 198.657 1.00 32.15  ? 281 PHE B CZ  1 
ATOM   3786 N N   . LEU B 1 282 ? 181.048 206.102 196.273 1.00 40.95  ? 282 LEU B N   1 
ATOM   3787 C CA  . LEU B 1 282 ? 181.485 205.166 197.306 1.00 12.85  ? 282 LEU B CA  1 
ATOM   3788 C C   . LEU B 1 282 ? 182.864 205.537 197.844 1.00 12.77  ? 282 LEU B C   1 
ATOM   3789 O O   . LEU B 1 282 ? 183.096 205.494 199.060 1.00 34.74  ? 282 LEU B O   1 
ATOM   3790 C CB  . LEU B 1 282 ? 181.482 203.739 196.760 1.00 9.16   ? 282 LEU B CB  1 
ATOM   3791 C CG  . LEU B 1 282 ? 180.263 202.885 197.112 1.00 2.92   ? 282 LEU B CG  1 
ATOM   3792 C CD1 . LEU B 1 282 ? 180.115 202.765 198.618 1.00 11.94  ? 282 LEU B CD1 1 
ATOM   3793 C CD2 . LEU B 1 282 ? 179.001 203.458 196.493 1.00 27.16  ? 282 LEU B CD2 1 
ATOM   3794 N N   . PHE B 1 283 ? 183.789 205.910 196.958 1.00 22.22  ? 283 PHE B N   1 
ATOM   3795 C CA  . PHE B 1 283 ? 185.126 206.301 197.404 1.00 16.80  ? 283 PHE B CA  1 
ATOM   3796 C C   . PHE B 1 283 ? 185.072 207.556 198.274 1.00 26.91  ? 283 PHE B C   1 
ATOM   3797 O O   . PHE B 1 283 ? 185.709 207.628 199.336 1.00 38.80  ? 283 PHE B O   1 
ATOM   3798 C CB  . PHE B 1 283 ? 186.029 206.514 196.189 1.00 28.71  ? 283 PHE B CB  1 
ATOM   3799 C CG  . PHE B 1 283 ? 187.368 207.105 196.517 1.00 26.45  ? 283 PHE B CG  1 
ATOM   3800 C CD1 . PHE B 1 283 ? 188.237 206.453 197.373 1.00 34.71  ? 283 PHE B CD1 1 
ATOM   3801 C CD2 . PHE B 1 283 ? 187.763 208.309 195.959 1.00 33.37  ? 283 PHE B CD2 1 
ATOM   3802 C CE1 . PHE B 1 283 ? 189.472 206.994 197.673 1.00 42.83  ? 283 PHE B CE1 1 
ATOM   3803 C CE2 . PHE B 1 283 ? 188.996 208.854 196.255 1.00 33.17  ? 283 PHE B CE2 1 
ATOM   3804 C CZ  . PHE B 1 283 ? 189.852 208.196 197.112 1.00 38.29  ? 283 PHE B CZ  1 
ATOM   3805 N N   . LEU B 1 284 ? 184.297 208.554 197.845 1.00 27.07  ? 284 LEU B N   1 
ATOM   3806 C CA  . LEU B 1 284 ? 184.169 209.782 198.619 1.00 31.59  ? 284 LEU B CA  1 
ATOM   3807 C C   . LEU B 1 284 ? 183.450 209.537 199.936 1.00 35.31  ? 284 LEU B C   1 
ATOM   3808 O O   . LEU B 1 284 ? 183.732 210.209 200.930 1.00 42.14  ? 284 LEU B O   1 
ATOM   3809 C CB  . LEU B 1 284 ? 183.439 210.844 197.796 1.00 32.74  ? 284 LEU B CB  1 
ATOM   3810 C CG  . LEU B 1 284 ? 184.303 211.865 197.050 1.00 29.40  ? 284 LEU B CG  1 
ATOM   3811 C CD1 . LEU B 1 284 ? 185.526 211.214 196.429 1.00 34.34  ? 284 LEU B CD1 1 
ATOM   3812 C CD2 . LEU B 1 284 ? 183.482 212.565 195.984 1.00 35.20  ? 284 LEU B CD2 1 
ATOM   3813 N N   . LEU B 1 285 ? 182.531 208.571 199.973 1.00 30.99  ? 285 LEU B N   1 
ATOM   3814 C CA  . LEU B 1 285 ? 181.868 208.224 201.223 1.00 31.44  ? 285 LEU B CA  1 
ATOM   3815 C C   . LEU B 1 285 ? 182.827 207.533 202.181 1.00 34.51  ? 285 LEU B C   1 
ATOM   3816 O O   . LEU B 1 285 ? 182.742 207.722 203.399 1.00 36.37  ? 285 LEU B O   1 
ATOM   3817 C CB  . LEU B 1 285 ? 180.659 207.339 200.938 1.00 19.07  ? 285 LEU B CB  1 
ATOM   3818 C CG  . LEU B 1 285 ? 179.549 207.338 201.984 1.00 20.94  ? 285 LEU B CG  1 
ATOM   3819 C CD1 . LEU B 1 285 ? 179.466 208.680 202.693 1.00 29.74  ? 285 LEU B CD1 1 
ATOM   3820 C CD2 . LEU B 1 285 ? 178.246 207.022 201.297 1.00 25.88  ? 285 LEU B CD2 1 
ATOM   3821 N N   . GLY B 1 286 ? 183.737 206.714 201.653 1.00 27.24  ? 286 GLY B N   1 
ATOM   3822 C CA  . GLY B 1 286 ? 184.796 206.178 202.492 1.00 11.96  ? 286 GLY B CA  1 
ATOM   3823 C C   . GLY B 1 286 ? 185.674 207.271 203.073 1.00 17.16  ? 286 GLY B C   1 
ATOM   3824 O O   . GLY B 1 286 ? 186.016 207.248 204.261 1.00 45.76  ? 286 GLY B O   1 
ATOM   3825 N N   . ILE B 1 287 ? 186.045 208.249 202.242 1.00 8.75   ? 287 ILE B N   1 
ATOM   3826 C CA  . ILE B 1 287 ? 186.799 209.397 202.746 1.00 11.14  ? 287 ILE B CA  1 
ATOM   3827 C C   . ILE B 1 287 ? 185.998 210.130 203.817 1.00 40.88  ? 287 ILE B C   1 
ATOM   3828 O O   . ILE B 1 287 ? 186.549 210.586 204.828 1.00 47.29  ? 287 ILE B O   1 
ATOM   3829 C CB  . ILE B 1 287 ? 187.187 210.339 201.591 1.00 18.87  ? 287 ILE B CB  1 
ATOM   3830 C CG1 . ILE B 1 287 ? 188.004 209.595 200.536 1.00 35.40  ? 287 ILE B CG1 1 
ATOM   3831 C CG2 . ILE B 1 287 ? 187.975 211.528 202.117 1.00 23.89  ? 287 ILE B CG2 1 
ATOM   3832 C CD1 . ILE B 1 287 ? 188.494 210.485 199.418 1.00 29.74  ? 287 ILE B CD1 1 
ATOM   3833 N N   . ASN B 1 288 ? 184.686 210.257 203.606 1.00 47.76  ? 288 ASN B N   1 
ATOM   3834 C CA  . ASN B 1 288 ? 183.818 210.904 204.584 1.00 32.63  ? 288 ASN B CA  1 
ATOM   3835 C C   . ASN B 1 288 ? 183.825 210.158 205.909 1.00 43.01  ? 288 ASN B C   1 
ATOM   3836 O O   . ASN B 1 288 ? 183.900 210.775 206.974 1.00 54.41  ? 288 ASN B O   1 
ATOM   3837 C CB  . ASN B 1 288 ? 182.391 210.988 204.043 1.00 26.17  ? 288 ASN B CB  1 
ATOM   3838 C CG  . ASN B 1 288 ? 182.081 212.328 203.424 1.00 36.10  ? 288 ASN B CG  1 
ATOM   3839 O OD1 . ASN B 1 288 ? 182.773 213.310 203.670 1.00 39.66  ? 288 ASN B OD1 1 
ATOM   3840 N ND2 . ASN B 1 288 ? 181.034 212.376 202.610 1.00 48.94  ? 288 ASN B ND2 1 
ATOM   3841 N N   . THR B 1 289 ? 183.726 208.830 205.860 1.00 37.61  ? 289 THR B N   1 
ATOM   3842 C CA  . THR B 1 289 ? 183.730 208.041 207.088 1.00 23.82  ? 289 THR B CA  1 
ATOM   3843 C C   . THR B 1 289 ? 185.056 208.180 207.822 1.00 18.19  ? 289 THR B C   1 
ATOM   3844 O O   . THR B 1 289 ? 185.083 208.299 209.054 1.00 27.96  ? 289 THR B O   1 
ATOM   3845 C CB  . THR B 1 289 ? 183.438 206.575 206.773 1.00 30.73  ? 289 THR B CB  1 
ATOM   3846 O OG1 . THR B 1 289 ? 182.177 206.473 206.100 1.00 38.47  ? 289 THR B OG1 1 
ATOM   3847 C CG2 . THR B 1 289 ? 183.384 205.757 208.051 1.00 28.13  ? 289 THR B CG2 1 
ATOM   3848 N N   . TYR B 1 290 ? 186.168 208.173 207.082 1.00 35.55  ? 290 TYR B N   1 
ATOM   3849 C CA  . TYR B 1 290 ? 187.469 208.386 207.713 1.00 37.88  ? 290 TYR B CA  1 
ATOM   3850 C C   . TYR B 1 290 ? 187.532 209.747 208.395 1.00 32.85  ? 290 TYR B C   1 
ATOM   3851 O O   . TYR B 1 290 ? 187.944 209.857 209.559 1.00 53.98  ? 290 TYR B O   1 
ATOM   3852 C CB  . TYR B 1 290 ? 188.588 208.257 206.680 1.00 45.51  ? 290 TYR B CB  1 
ATOM   3853 C CG  . TYR B 1 290 ? 189.837 209.028 207.049 1.00 46.64  ? 290 TYR B CG  1 
ATOM   3854 C CD1 . TYR B 1 290 ? 190.728 208.535 207.991 1.00 45.45  ? 290 TYR B CD1 1 
ATOM   3855 C CD2 . TYR B 1 290 ? 190.128 210.247 206.449 1.00 51.32  ? 290 TYR B CD2 1 
ATOM   3856 C CE1 . TYR B 1 290 ? 191.869 209.237 208.330 1.00 45.49  ? 290 TYR B CE1 1 
ATOM   3857 C CE2 . TYR B 1 290 ? 191.267 210.954 206.782 1.00 44.10  ? 290 TYR B CE2 1 
ATOM   3858 C CZ  . TYR B 1 290 ? 192.134 210.444 207.723 1.00 43.38  ? 290 TYR B CZ  1 
ATOM   3859 O OH  . TYR B 1 290 ? 193.270 211.143 208.058 1.00 49.07  ? 290 TYR B OH  1 
ATOM   3860 N N   . GLY B 1 291 ? 187.129 210.799 207.679 1.00 27.23  ? 291 GLY B N   1 
ATOM   3861 C CA  . GLY B 1 291 ? 187.164 212.132 208.257 1.00 44.66  ? 291 GLY B CA  1 
ATOM   3862 C C   . GLY B 1 291 ? 186.258 212.262 209.464 1.00 46.97  ? 291 GLY B C   1 
ATOM   3863 O O   . GLY B 1 291 ? 186.595 212.944 210.434 1.00 44.83  ? 291 GLY B O   1 
ATOM   3864 N N   . TRP B 1 292 ? 185.100 211.604 209.425 1.00 52.62  ? 292 TRP B N   1 
ATOM   3865 C CA  . TRP B 1 292 ? 184.186 211.640 210.559 1.00 44.73  ? 292 TRP B CA  1 
ATOM   3866 C C   . TRP B 1 292 ? 184.792 210.956 211.775 1.00 49.39  ? 292 TRP B C   1 
ATOM   3867 O O   . TRP B 1 292 ? 184.785 211.508 212.881 1.00 52.74  ? 292 TRP B O   1 
ATOM   3868 C CB  . TRP B 1 292 ? 182.853 210.989 210.190 1.00 38.77  ? 292 TRP B CB  1 
ATOM   3869 C CG  . TRP B 1 292 ? 182.102 211.699 209.114 1.00 37.94  ? 292 TRP B CG  1 
ATOM   3870 C CD1 . TRP B 1 292 ? 182.301 212.976 208.680 1.00 41.83  ? 292 TRP B CD1 1 
ATOM   3871 C CD2 . TRP B 1 292 ? 181.022 211.174 208.335 1.00 41.57  ? 292 TRP B CD2 1 
ATOM   3872 N NE1 . TRP B 1 292 ? 181.415 213.277 207.675 1.00 45.41  ? 292 TRP B NE1 1 
ATOM   3873 C CE2 . TRP B 1 292 ? 180.619 212.187 207.445 1.00 47.61  ? 292 TRP B CE2 1 
ATOM   3874 C CE3 . TRP B 1 292 ? 180.358 209.944 208.303 1.00 46.01  ? 292 TRP B CE3 1 
ATOM   3875 C CZ2 . TRP B 1 292 ? 179.582 212.008 206.534 1.00 57.17  ? 292 TRP B CZ2 1 
ATOM   3876 C CZ3 . TRP B 1 292 ? 179.330 209.769 207.397 1.00 45.41  ? 292 TRP B CZ3 1 
ATOM   3877 C CH2 . TRP B 1 292 ? 178.952 210.795 206.526 1.00 57.91  ? 292 TRP B CH2 1 
ATOM   3878 N N   . ARG B 1 293 ? 185.322 209.746 211.590 1.00 51.25  ? 293 ARG B N   1 
ATOM   3879 C CA  . ARG B 1 293 ? 185.839 209.006 212.735 1.00 48.52  ? 293 ARG B CA  1 
ATOM   3880 C C   . ARG B 1 293 ? 187.110 209.632 213.291 1.00 50.87  ? 293 ARG B C   1 
ATOM   3881 O O   . ARG B 1 293 ? 187.419 209.443 214.473 1.00 61.01  ? 293 ARG B O   1 
ATOM   3882 C CB  . ARG B 1 293 ? 186.087 207.547 212.360 1.00 54.71  ? 293 ARG B CB  1 
ATOM   3883 C CG  . ARG B 1 293 ? 184.941 206.622 212.733 1.00 53.39  ? 293 ARG B CG  1 
ATOM   3884 C CD  . ARG B 1 293 ? 185.457 205.349 213.375 1.00 57.28  ? 293 ARG B CD  1 
ATOM   3885 N NE  . ARG B 1 293 ? 186.455 204.693 212.541 1.00 61.58  ? 293 ARG B NE  1 
ATOM   3886 C CZ  . ARG B 1 293 ? 186.174 203.832 211.574 1.00 65.04  ? 293 ARG B CZ  1 
ATOM   3887 N NH1 . ARG B 1 293 ? 184.927 203.489 211.296 1.00 63.39  ? 293 ARG B NH1 1 
ATOM   3888 N NH2 . ARG B 1 293 ? 187.168 203.304 210.867 1.00 62.86  ? 293 ARG B NH2 1 
ATOM   3889 N N   . GLN B 1 294 ? 187.858 210.375 212.475 1.00 49.43  ? 294 GLN B N   1 
ATOM   3890 C CA  . GLN B 1 294 ? 189.076 210.991 212.987 1.00 51.54  ? 294 GLN B CA  1 
ATOM   3891 C C   . GLN B 1 294 ? 188.864 212.403 213.518 1.00 56.57  ? 294 GLN B C   1 
ATOM   3892 O O   . GLN B 1 294 ? 189.632 212.851 214.376 1.00 61.92  ? 294 GLN B O   1 
ATOM   3893 C CB  . GLN B 1 294 ? 190.159 211.004 211.905 1.00 54.91  ? 294 GLN B CB  1 
ATOM   3894 C CG  . GLN B 1 294 ? 190.666 209.620 211.539 1.00 59.36  ? 294 GLN B CG  1 
ATOM   3895 C CD  . GLN B 1 294 ? 191.513 208.995 212.633 1.00 59.87  ? 294 GLN B CD  1 
ATOM   3896 O OE1 . GLN B 1 294 ? 191.998 209.685 213.530 1.00 59.96  ? 294 GLN B OE1 1 
ATOM   3897 N NE2 . GLN B 1 294 ? 191.691 207.681 212.564 1.00 58.38  ? 294 GLN B NE2 1 
ATOM   3898 N N   . ALA B 1 295 ? 187.847 213.119 213.033 1.00 61.81  ? 295 ALA B N   1 
ATOM   3899 C CA  . ALA B 1 295 ? 187.620 214.481 213.505 1.00 65.18  ? 295 ALA B CA  1 
ATOM   3900 C C   . ALA B 1 295 ? 187.017 214.497 214.904 1.00 60.34  ? 295 ALA B C   1 
ATOM   3901 O O   . ALA B 1 295 ? 187.428 215.296 215.754 1.00 59.36  ? 295 ALA B O   1 
ATOM   3902 C CB  . ALA B 1 295 ? 186.722 215.232 212.524 1.00 67.72  ? 295 ALA B CB  1 
ATOM   3903 N N   . GLY B 1 296 ? 186.046 213.626 215.166 1.00 57.85  ? 296 GLY B N   1 
ATOM   3904 C CA  . GLY B 1 296 ? 185.397 213.593 216.461 1.00 59.16  ? 296 GLY B CA  1 
ATOM   3905 C C   . GLY B 1 296 ? 183.891 213.448 216.379 1.00 62.17  ? 296 GLY B C   1 
ATOM   3906 O O   . GLY B 1 296 ? 183.245 213.056 217.355 1.00 64.99  ? 296 GLY B O   1 
ATOM   3907 N N   . VAL B 1 297 ? 183.321 213.772 215.216 1.00 56.80  ? 297 VAL B N   1 
ATOM   3908 C CA  . VAL B 1 297 ? 181.885 213.620 215.016 1.00 58.69  ? 297 VAL B CA  1 
ATOM   3909 C C   . VAL B 1 297 ? 181.491 212.156 215.147 1.00 57.40  ? 297 VAL B C   1 
ATOM   3910 O O   . VAL B 1 297 ? 182.121 211.263 214.565 1.00 62.60  ? 297 VAL B O   1 
ATOM   3911 C CB  . VAL B 1 297 ? 181.474 214.220 213.662 1.00 49.65  ? 297 VAL B CB  1 
ATOM   3912 C CG1 . VAL B 1 297 ? 182.286 213.629 212.561 1.00 56.18  ? 297 VAL B CG1 1 
ATOM   3913 C CG2 . VAL B 1 297 ? 180.018 213.926 213.377 1.00 48.24  ? 297 VAL B CG2 1 
ATOM   3914 N N   . ASN B 1 298 ? 180.448 211.903 215.939 1.00 62.48  ? 298 ASN B N   1 
ATOM   3915 C CA  . ASN B 1 298 ? 179.991 210.548 216.247 1.00 56.19  ? 298 ASN B CA  1 
ATOM   3916 C C   . ASN B 1 298 ? 178.933 210.149 215.223 1.00 53.55  ? 298 ASN B C   1 
ATOM   3917 O O   . ASN B 1 298 ? 177.726 210.204 215.467 1.00 63.40  ? 298 ASN B O   1 
ATOM   3918 C CB  . ASN B 1 298 ? 179.461 210.486 217.675 1.00 61.69  ? 298 ASN B CB  1 
ATOM   3919 C CG  . ASN B 1 298 ? 179.263 209.068 218.166 1.00 68.59  ? 298 ASN B CG  1 
ATOM   3920 O OD1 . ASN B 1 298 ? 179.341 208.115 217.396 1.00 70.49  ? 298 ASN B OD1 1 
ATOM   3921 N ND2 . ASN B 1 298 ? 179.007 208.923 219.461 1.00 64.14  ? 298 ASN B ND2 1 
ATOM   3922 N N   . HIS B 1 299 ? 179.408 209.732 214.046 1.00 49.47  ? 299 HIS B N   1 
ATOM   3923 C CA  . HIS B 1 299 ? 178.498 209.443 212.941 1.00 55.98  ? 299 HIS B CA  1 
ATOM   3924 C C   . HIS B 1 299 ? 177.663 208.195 213.205 1.00 57.91  ? 299 HIS B C   1 
ATOM   3925 O O   . HIS B 1 299 ? 176.498 208.127 212.797 1.00 59.25  ? 299 HIS B O   1 
ATOM   3926 C CB  . HIS B 1 299 ? 179.282 209.299 211.637 1.00 55.40  ? 299 HIS B CB  1 
ATOM   3927 C CG  . HIS B 1 299 ? 180.068 208.029 211.540 1.00 52.60  ? 299 HIS B CG  1 
ATOM   3928 N ND1 . HIS B 1 299 ? 179.765 207.035 210.635 1.00 54.42  ? 299 HIS B ND1 1 
ATOM   3929 C CD2 . HIS B 1 299 ? 181.147 207.593 212.231 1.00 55.27  ? 299 HIS B CD2 1 
ATOM   3930 C CE1 . HIS B 1 299 ? 180.622 206.040 210.774 1.00 60.98  ? 299 HIS B CE1 1 
ATOM   3931 N NE2 . HIS B 1 299 ? 181.471 206.353 211.736 1.00 62.13  ? 299 HIS B NE2 1 
ATOM   3932 N N   . VAL B 1 300 ? 178.238 207.192 213.876 1.00 61.90  ? 300 VAL B N   1 
ATOM   3933 C CA  . VAL B 1 300 ? 177.501 205.954 214.120 1.00 60.17  ? 300 VAL B CA  1 
ATOM   3934 C C   . VAL B 1 300 ? 176.304 206.207 215.027 1.00 63.06  ? 300 VAL B C   1 
ATOM   3935 O O   . VAL B 1 300 ? 175.225 205.639 214.818 1.00 64.32  ? 300 VAL B O   1 
ATOM   3936 C CB  . VAL B 1 300 ? 178.440 204.869 214.690 1.00 62.10  ? 300 VAL B CB  1 
ATOM   3937 C CG1 . VAL B 1 300 ? 179.237 205.399 215.867 1.00 59.46  ? 300 VAL B CG1 1 
ATOM   3938 C CG2 . VAL B 1 300 ? 177.652 203.629 215.089 1.00 64.41  ? 300 VAL B CG2 1 
ATOM   3939 N N   . LEU B 1 301 ? 176.464 207.064 216.037 1.00 61.60  ? 301 LEU B N   1 
ATOM   3940 C CA  . LEU B 1 301 ? 175.331 207.449 216.871 1.00 58.12  ? 301 LEU B CA  1 
ATOM   3941 C C   . LEU B 1 301 ? 174.296 208.236 216.076 1.00 52.35  ? 301 LEU B C   1 
ATOM   3942 O O   . LEU B 1 301 ? 173.089 208.017 216.235 1.00 54.85  ? 301 LEU B O   1 
ATOM   3943 C CB  . LEU B 1 301 ? 175.817 208.265 218.070 1.00 53.88  ? 301 LEU B CB  1 
ATOM   3944 C CG  . LEU B 1 301 ? 174.805 209.198 218.741 1.00 54.31  ? 301 LEU B CG  1 
ATOM   3945 C CD1 . LEU B 1 301 ? 173.747 208.403 219.493 1.00 55.52  ? 301 LEU B CD1 1 
ATOM   3946 C CD2 . LEU B 1 301 ? 175.507 210.178 219.669 1.00 57.86  ? 301 LEU B CD2 1 
ATOM   3947 N N   . ILE B 1 302 ? 174.749 209.153 215.219 1.00 42.38  ? 302 ILE B N   1 
ATOM   3948 C CA  . ILE B 1 302 ? 173.827 209.983 214.446 1.00 41.31  ? 302 ILE B CA  1 
ATOM   3949 C C   . ILE B 1 302 ? 173.051 209.126 213.452 1.00 41.26  ? 302 ILE B C   1 
ATOM   3950 O O   . ILE B 1 302 ? 171.825 209.232 213.333 1.00 45.22  ? 302 ILE B O   1 
ATOM   3951 C CB  . ILE B 1 302 ? 174.590 211.115 213.738 1.00 36.64  ? 302 ILE B CB  1 
ATOM   3952 C CG1 . ILE B 1 302 ? 175.175 212.085 214.762 1.00 36.80  ? 302 ILE B CG1 1 
ATOM   3953 C CG2 . ILE B 1 302 ? 173.672 211.869 212.804 1.00 49.02  ? 302 ILE B CG2 1 
ATOM   3954 C CD1 . ILE B 1 302 ? 176.222 213.006 214.186 1.00 40.77  ? 302 ILE B CD1 1 
ATOM   3955 N N   . PHE B 1 303 ? 173.758 208.257 212.726 1.00 46.42  ? 303 PHE B N   1 
ATOM   3956 C CA  . PHE B 1 303 ? 173.104 207.375 211.766 1.00 50.98  ? 303 PHE B CA  1 
ATOM   3957 C C   . PHE B 1 303 ? 172.304 206.270 212.441 1.00 57.33  ? 303 PHE B C   1 
ATOM   3958 O O   . PHE B 1 303 ? 171.587 205.535 211.753 1.00 58.75  ? 303 PHE B O   1 
ATOM   3959 C CB  . PHE B 1 303 ? 174.137 206.750 210.827 1.00 54.79  ? 303 PHE B CB  1 
ATOM   3960 C CG  . PHE B 1 303 ? 174.488 207.606 209.646 1.00 44.38  ? 303 PHE B CG  1 
ATOM   3961 C CD1 . PHE B 1 303 ? 175.306 208.712 209.791 1.00 49.75  ? 303 PHE B CD1 1 
ATOM   3962 C CD2 . PHE B 1 303 ? 174.004 207.298 208.387 1.00 40.67  ? 303 PHE B CD2 1 
ATOM   3963 C CE1 . PHE B 1 303 ? 175.632 209.495 208.703 1.00 48.62  ? 303 PHE B CE1 1 
ATOM   3964 C CE2 . PHE B 1 303 ? 174.326 208.079 207.297 1.00 44.65  ? 303 PHE B CE2 1 
ATOM   3965 C CZ  . PHE B 1 303 ? 175.141 209.178 207.455 1.00 46.67  ? 303 PHE B CZ  1 
ATOM   3966 N N   . GLU B 1 304 ? 172.425 206.128 213.763 1.00 65.61  ? 304 GLU B N   1 
ATOM   3967 C CA  . GLU B 1 304 ? 171.779 205.059 214.525 1.00 66.20  ? 304 GLU B CA  1 
ATOM   3968 C C   . GLU B 1 304 ? 172.248 203.677 214.080 1.00 66.14  ? 304 GLU B C   1 
ATOM   3969 O O   . GLU B 1 304 ? 171.474 202.718 214.091 1.00 67.71  ? 304 GLU B O   1 
ATOM   3970 C CB  . GLU B 1 304 ? 170.251 205.150 214.445 1.00 62.31  ? 304 GLU B CB  1 
ATOM   3971 C CG  . GLU B 1 304 ? 169.673 206.459 214.954 1.00 62.19  ? 304 GLU B CG  1 
ATOM   3972 C CD  . GLU B 1 304 ? 168.443 206.890 214.179 1.00 65.68  ? 304 GLU B CD  1 
ATOM   3973 O OE1 . GLU B 1 304 ? 167.825 206.029 213.519 1.00 67.88  ? 304 GLU B OE1 1 
ATOM   3974 O OE2 . GLU B 1 304 ? 168.095 208.088 214.231 1.00 64.14  ? 304 GLU B OE2 1 
ATOM   3975 N N   . LEU B 1 305 ? 173.513 203.564 213.686 1.00 66.14  ? 305 LEU B N   1 
ATOM   3976 C CA  . LEU B 1 305 ? 174.076 202.277 213.316 1.00 67.17  ? 305 LEU B CA  1 
ATOM   3977 C C   . LEU B 1 305 ? 174.394 201.457 214.563 1.00 69.47  ? 305 LEU B C   1 
ATOM   3978 O O   . LEU B 1 305 ? 174.362 201.953 215.692 1.00 68.48  ? 305 LEU B O   1 
ATOM   3979 C CB  . LEU B 1 305 ? 175.345 202.455 212.481 1.00 67.69  ? 305 LEU B CB  1 
ATOM   3980 C CG  . LEU B 1 305 ? 175.276 203.349 211.244 1.00 66.69  ? 305 LEU B CG  1 
ATOM   3981 C CD1 . LEU B 1 305 ? 176.619 204.016 210.998 1.00 62.13  ? 305 LEU B CD1 1 
ATOM   3982 C CD2 . LEU B 1 305 ? 174.843 202.549 210.027 1.00 70.93  ? 305 LEU B CD2 1 
ATOM   3983 N N   . ASN B 1 306 ? 174.701 200.189 214.344 1.00 81.86  ? 306 ASN B N   1 
ATOM   3984 C CA  . ASN B 1 306 ? 175.136 199.325 215.431 1.00 83.73  ? 306 ASN B CA  1 
ATOM   3985 C C   . ASN B 1 306 ? 176.551 199.715 215.835 1.00 85.63  ? 306 ASN B C   1 
ATOM   3986 O O   . ASN B 1 306 ? 177.453 199.673 214.987 1.00 83.80  ? 306 ASN B O   1 
ATOM   3987 C CB  . ASN B 1 306 ? 175.080 197.861 214.997 1.00 82.68  ? 306 ASN B CB  1 
ATOM   3988 C CG  . ASN B 1 306 ? 175.318 196.897 216.144 1.00 84.90  ? 306 ASN B CG  1 
ATOM   3989 O OD1 . ASN B 1 306 ? 175.450 197.303 217.298 1.00 86.88  ? 306 ASN B OD1 1 
ATOM   3990 N ND2 . ASN B 1 306 ? 175.371 195.608 215.829 1.00 85.24  ? 306 ASN B ND2 1 
ATOM   3991 N N   . PRO B 1 307 ? 176.794 200.109 217.088 1.00 87.48  ? 307 PRO B N   1 
ATOM   3992 C CA  . PRO B 1 307 ? 178.153 200.530 217.472 1.00 87.10  ? 307 PRO B CA  1 
ATOM   3993 C C   . PRO B 1 307 ? 179.207 199.451 217.284 1.00 90.20  ? 307 PRO B C   1 
ATOM   3994 O O   . PRO B 1 307 ? 180.365 199.769 216.986 1.00 92.37  ? 307 PRO B O   1 
ATOM   3995 C CB  . PRO B 1 307 ? 177.989 200.911 218.950 1.00 86.79  ? 307 PRO B CB  1 
ATOM   3996 C CG  . PRO B 1 307 ? 176.545 201.255 219.095 1.00 84.40  ? 307 PRO B CG  1 
ATOM   3997 C CD  . PRO B 1 307 ? 175.818 200.327 218.169 1.00 84.89  ? 307 PRO B CD  1 
ATOM   3998 N N   . ARG B 1 308 ? 178.839 198.182 217.450 1.00 92.36  ? 308 ARG B N   1 
ATOM   3999 C CA  . ARG B 1 308 ? 179.802 197.093 217.342 1.00 91.78  ? 308 ARG B CA  1 
ATOM   4000 C C   . ARG B 1 308 ? 180.014 196.624 215.910 1.00 89.61  ? 308 ARG B C   1 
ATOM   4001 O O   . ARG B 1 308 ? 181.087 196.098 215.592 1.00 90.57  ? 308 ARG B O   1 
ATOM   4002 C CB  . ARG B 1 308 ? 179.358 195.907 218.204 1.00 92.68  ? 308 ARG B CB  1 
ATOM   4003 C CG  . ARG B 1 308 ? 178.618 196.290 219.480 1.00 90.81  ? 308 ARG B CG  1 
ATOM   4004 C CD  . ARG B 1 308 ? 179.483 197.138 220.403 1.00 90.19  ? 308 ARG B CD  1 
ATOM   4005 N NE  . ARG B 1 308 ? 180.521 196.352 221.060 1.00 91.55  ? 308 ARG B NE  1 
ATOM   4006 C CZ  . ARG B 1 308 ? 181.645 196.858 221.549 1.00 93.08  ? 308 ARG B CZ  1 
ATOM   4007 N NH1 . ARG B 1 308 ? 181.911 198.151 221.472 1.00 90.43  ? 308 ARG B NH1 1 
ATOM   4008 N NH2 . ARG B 1 308 ? 182.523 196.045 222.129 1.00 93.66  ? 308 ARG B NH2 1 
ATOM   4009 N N   . SER B 1 309 ? 179.021 196.799 215.036 1.00 83.37  ? 309 SER B N   1 
ATOM   4010 C CA  . SER B 1 309 ? 179.086 196.301 213.668 1.00 86.43  ? 309 SER B CA  1 
ATOM   4011 C C   . SER B 1 309 ? 179.183 197.423 212.638 1.00 89.66  ? 309 SER B C   1 
ATOM   4012 O O   . SER B 1 309 ? 178.809 197.226 211.478 1.00 91.28  ? 309 SER B O   1 
ATOM   4013 C CB  . SER B 1 309 ? 177.875 195.416 213.370 1.00 89.37  ? 309 SER B CB  1 
ATOM   4014 O OG  . SER B 1 309 ? 177.903 194.947 212.034 1.00 90.59  ? 309 SER B OG  1 
ATOM   4015 N N   . ASN B 1 310 ? 179.675 198.594 213.036 1.00 84.11  ? 310 ASN B N   1 
ATOM   4016 C CA  . ASN B 1 310 ? 179.813 199.697 212.095 1.00 84.56  ? 310 ASN B CA  1 
ATOM   4017 C C   . ASN B 1 310 ? 180.895 199.389 211.066 1.00 85.63  ? 310 ASN B C   1 
ATOM   4018 O O   . ASN B 1 310 ? 181.841 198.640 211.328 1.00 82.19  ? 310 ASN B O   1 
ATOM   4019 C CB  . ASN B 1 310 ? 180.142 200.993 212.836 1.00 77.64  ? 310 ASN B CB  1 
ATOM   4020 C CG  . ASN B 1 310 ? 181.592 201.065 213.270 1.00 78.36  ? 310 ASN B CG  1 
ATOM   4021 O OD1 . ASN B 1 310 ? 182.079 200.197 213.993 1.00 83.74  ? 310 ASN B OD1 1 
ATOM   4022 N ND2 . ASN B 1 310 ? 182.290 202.105 212.829 1.00 74.37  ? 310 ASN B ND2 1 
ATOM   4023 N N   . LEU B 1 311 ? 180.747 199.975 209.881 1.00 75.63  ? 311 LEU B N   1 
ATOM   4024 C CA  . LEU B 1 311 ? 181.674 199.764 208.777 1.00 70.43  ? 311 LEU B CA  1 
ATOM   4025 C C   . LEU B 1 311 ? 182.760 200.831 208.816 1.00 74.47  ? 311 LEU B C   1 
ATOM   4026 O O   . LEU B 1 311 ? 182.461 202.029 208.796 1.00 73.87  ? 311 LEU B O   1 
ATOM   4027 C CB  . LEU B 1 311 ? 180.946 199.799 207.433 1.00 65.53  ? 311 LEU B CB  1 
ATOM   4028 C CG  . LEU B 1 311 ? 180.375 198.483 206.905 1.00 69.73  ? 311 LEU B CG  1 
ATOM   4029 C CD1 . LEU B 1 311 ? 180.209 198.554 205.396 1.00 68.67  ? 311 LEU B CD1 1 
ATOM   4030 C CD2 . LEU B 1 311 ? 181.261 197.311 207.294 1.00 73.61  ? 311 LEU B CD2 1 
ATOM   4031 N N   . SER B 1 312 ? 184.014 200.392 208.870 1.00 66.72  ? 312 SER B N   1 
ATOM   4032 C CA  . SER B 1 312 ? 185.130 201.316 208.795 1.00 61.94  ? 312 SER B CA  1 
ATOM   4033 C C   . SER B 1 312 ? 185.255 201.872 207.377 1.00 57.03  ? 312 SER B C   1 
ATOM   4034 O O   . SER B 1 312 ? 184.688 201.343 206.418 1.00 56.36  ? 312 SER B O   1 
ATOM   4035 C CB  . SER B 1 312 ? 186.426 200.623 209.212 1.00 57.95  ? 312 SER B CB  1 
ATOM   4036 O OG  . SER B 1 312 ? 186.280 199.980 210.466 1.00 61.91  ? 312 SER B OG  1 
ATOM   4037 N N   . HIS B 1 313 ? 186.011 202.964 207.253 1.00 43.19  ? 313 HIS B N   1 
ATOM   4038 C CA  . HIS B 1 313 ? 186.252 203.540 205.936 1.00 46.68  ? 313 HIS B CA  1 
ATOM   4039 C C   . HIS B 1 313 ? 187.032 202.597 205.033 1.00 48.56  ? 313 HIS B C   1 
ATOM   4040 O O   . HIS B 1 313 ? 186.934 202.710 203.806 1.00 53.88  ? 313 HIS B O   1 
ATOM   4041 C CB  . HIS B 1 313 ? 186.991 204.872 206.065 1.00 42.09  ? 313 HIS B CB  1 
ATOM   4042 C CG  . HIS B 1 313 ? 188.268 204.786 206.840 1.00 44.72  ? 313 HIS B CG  1 
ATOM   4043 N ND1 . HIS B 1 313 ? 188.300 204.591 208.203 1.00 57.32  ? 313 HIS B ND1 1 
ATOM   4044 C CD2 . HIS B 1 313 ? 189.559 204.876 206.442 1.00 47.47  ? 313 HIS B CD2 1 
ATOM   4045 C CE1 . HIS B 1 313 ? 189.555 204.562 208.613 1.00 59.36  ? 313 HIS B CE1 1 
ATOM   4046 N NE2 . HIS B 1 313 ? 190.339 204.732 207.563 1.00 58.44  ? 313 HIS B NE2 1 
ATOM   4047 N N   . GLN B 1 314 ? 187.794 201.666 205.611 1.00 53.59  ? 314 GLN B N   1 
ATOM   4048 C CA  . GLN B 1 314 ? 188.491 200.673 204.805 1.00 49.01  ? 314 GLN B CA  1 
ATOM   4049 C C   . GLN B 1 314 ? 187.517 199.778 204.050 1.00 48.29  ? 314 GLN B C   1 
ATOM   4050 O O   . GLN B 1 314 ? 187.770 199.433 202.893 1.00 57.75  ? 314 GLN B O   1 
ATOM   4051 C CB  . GLN B 1 314 ? 189.414 199.832 205.687 1.00 50.70  ? 314 GLN B CB  1 
ATOM   4052 C CG  . GLN B 1 314 ? 190.477 200.634 206.422 1.00 54.18  ? 314 GLN B CG  1 
ATOM   4053 C CD  . GLN B 1 314 ? 191.585 201.127 205.510 1.00 50.77  ? 314 GLN B CD  1 
ATOM   4054 O OE1 . GLN B 1 314 ? 191.619 200.806 204.322 1.00 40.93  ? 314 GLN B OE1 1 
ATOM   4055 N NE2 . GLN B 1 314 ? 192.500 201.912 206.064 1.00 54.84  ? 314 GLN B NE2 1 
ATOM   4056 N N   . HIS B 1 315 ? 186.405 199.393 204.681 1.00 42.72  ? 315 HIS B N   1 
ATOM   4057 C CA  . HIS B 1 315 ? 185.420 198.559 203.998 1.00 39.03  ? 315 HIS B CA  1 
ATOM   4058 C C   . HIS B 1 315 ? 184.766 199.304 202.839 1.00 50.16  ? 315 HIS B C   1 
ATOM   4059 O O   . HIS B 1 315 ? 184.557 198.731 201.762 1.00 57.90  ? 315 HIS B O   1 
ATOM   4060 C CB  . HIS B 1 315 ? 184.362 198.071 204.987 1.00 42.11  ? 315 HIS B CB  1 
ATOM   4061 C CG  . HIS B 1 315 ? 184.913 197.251 206.112 1.00 56.92  ? 315 HIS B CG  1 
ATOM   4062 N ND1 . HIS B 1 315 ? 184.357 196.050 206.496 1.00 61.13  ? 315 HIS B ND1 1 
ATOM   4063 C CD2 . HIS B 1 315 ? 185.963 197.461 206.941 1.00 55.49  ? 315 HIS B CD2 1 
ATOM   4064 C CE1 . HIS B 1 315 ? 185.044 195.552 207.510 1.00 54.91  ? 315 HIS B CE1 1 
ATOM   4065 N NE2 . HIS B 1 315 ? 186.023 196.389 207.799 1.00 55.36  ? 315 HIS B NE2 1 
ATOM   4066 N N   . LEU B 1 316 ? 184.428 200.580 203.042 1.00 47.29  ? 316 LEU B N   1 
ATOM   4067 C CA  . LEU B 1 316 ? 183.863 201.374 201.956 1.00 37.85  ? 316 LEU B CA  1 
ATOM   4068 C C   . LEU B 1 316 ? 184.866 201.541 200.824 1.00 28.86  ? 316 LEU B C   1 
ATOM   4069 O O   . LEU B 1 316 ? 184.506 201.446 199.644 1.00 32.24  ? 316 LEU B O   1 
ATOM   4070 C CB  . LEU B 1 316 ? 183.411 202.737 202.479 1.00 24.14  ? 316 LEU B CB  1 
ATOM   4071 C CG  . LEU B 1 316 ? 182.015 202.807 203.098 1.00 22.00  ? 316 LEU B CG  1 
ATOM   4072 C CD1 . LEU B 1 316 ? 181.585 204.253 203.272 1.00 27.90  ? 316 LEU B CD1 1 
ATOM   4073 C CD2 . LEU B 1 316 ? 181.009 202.046 202.250 1.00 24.90  ? 316 LEU B CD2 1 
ATOM   4074 N N   . PHE B 1 317 ? 186.133 201.790 201.165 1.00 24.40  ? 317 PHE B N   1 
ATOM   4075 C CA  . PHE B 1 317 ? 187.171 201.888 200.146 1.00 21.49  ? 317 PHE B CA  1 
ATOM   4076 C C   . PHE B 1 317 ? 187.307 200.581 199.375 1.00 29.78  ? 317 PHE B C   1 
ATOM   4077 O O   . PHE B 1 317 ? 187.475 200.589 198.152 1.00 22.10  ? 317 PHE B O   1 
ATOM   4078 C CB  . PHE B 1 317 ? 188.504 202.263 200.792 1.00 24.73  ? 317 PHE B CB  1 
ATOM   4079 C CG  . PHE B 1 317 ? 188.615 203.709 201.167 1.00 16.94  ? 317 PHE B CG  1 
ATOM   4080 C CD1 . PHE B 1 317 ? 188.002 204.687 200.407 1.00 25.79  ? 317 PHE B CD1 1 
ATOM   4081 C CD2 . PHE B 1 317 ? 189.344 204.091 202.279 1.00 40.26  ? 317 PHE B CD2 1 
ATOM   4082 C CE1 . PHE B 1 317 ? 188.108 206.019 200.755 1.00 42.76  ? 317 PHE B CE1 1 
ATOM   4083 C CE2 . PHE B 1 317 ? 189.454 205.420 202.631 1.00 35.93  ? 317 PHE B CE2 1 
ATOM   4084 C CZ  . PHE B 1 317 ? 188.836 206.385 201.867 1.00 39.25  ? 317 PHE B CZ  1 
ATOM   4085 N N   . GLU B 1 318 ? 187.243 199.448 200.077 1.00 50.25  ? 318 GLU B N   1 
ATOM   4086 C CA  . GLU B 1 318 ? 187.354 198.147 199.424 1.00 42.21  ? 318 GLU B CA  1 
ATOM   4087 C C   . GLU B 1 318 ? 186.186 197.903 198.476 1.00 44.77  ? 318 GLU B C   1 
ATOM   4088 O O   . GLU B 1 318 ? 186.371 197.403 197.360 1.00 50.80  ? 318 GLU B O   1 
ATOM   4089 C CB  . GLU B 1 318 ? 187.427 197.047 200.482 1.00 38.20  ? 318 GLU B CB  1 
ATOM   4090 C CG  . GLU B 1 318 ? 187.768 195.676 199.937 1.00 45.60  ? 318 GLU B CG  1 
ATOM   4091 C CD  . GLU B 1 318 ? 187.554 194.582 200.961 1.00 55.88  ? 318 GLU B CD  1 
ATOM   4092 O OE1 . GLU B 1 318 ? 188.154 194.663 202.053 1.00 54.43  ? 318 GLU B OE1 1 
ATOM   4093 O OE2 . GLU B 1 318 ? 186.781 193.643 200.676 1.00 57.30  ? 318 GLU B OE2 1 
ATOM   4094 N N   . ILE B 1 319 ? 184.970 198.238 198.913 1.00 43.81  ? 319 ILE B N   1 
ATOM   4095 C CA  . ILE B 1 319 ? 183.800 198.057 198.057 1.00 42.31  ? 319 ILE B CA  1 
ATOM   4096 C C   . ILE B 1 319 ? 183.903 198.944 196.823 1.00 48.52  ? 319 ILE B C   1 
ATOM   4097 O O   . ILE B 1 319 ? 183.630 198.505 195.696 1.00 50.61  ? 319 ILE B O   1 
ATOM   4098 C CB  . ILE B 1 319 ? 182.508 198.336 198.847 1.00 44.75  ? 319 ILE B CB  1 
ATOM   4099 C CG1 . ILE B 1 319 ? 182.221 197.194 199.822 1.00 55.95  ? 319 ILE B CG1 1 
ATOM   4100 C CG2 . ILE B 1 319 ? 181.335 198.529 197.901 1.00 50.28  ? 319 ILE B CG2 1 
ATOM   4101 C CD1 . ILE B 1 319 ? 180.856 197.274 200.472 1.00 58.86  ? 319 ILE B CD1 1 
ATOM   4102 N N   . ALA B 1 320 ? 184.306 200.203 197.015 1.00 40.71  ? 320 ALA B N   1 
ATOM   4103 C CA  . ALA B 1 320 ? 184.481 201.107 195.885 1.00 30.35  ? 320 ALA B CA  1 
ATOM   4104 C C   . ALA B 1 320 ? 185.540 200.585 194.927 1.00 39.54  ? 320 ALA B C   1 
ATOM   4105 O O   . ALA B 1 320 ? 185.358 200.630 193.707 1.00 47.10  ? 320 ALA B O   1 
ATOM   4106 C CB  . ALA B 1 320 ? 184.850 202.505 196.380 1.00 25.82  ? 320 ALA B CB  1 
ATOM   4107 N N   . GLY B 1 321 ? 186.649 200.073 195.462 1.00 36.51  ? 321 GLY B N   1 
ATOM   4108 C CA  . GLY B 1 321 ? 187.698 199.544 194.609 1.00 28.51  ? 321 GLY B CA  1 
ATOM   4109 C C   . GLY B 1 321 ? 187.255 198.332 193.813 1.00 28.08  ? 321 GLY B C   1 
ATOM   4110 O O   . GLY B 1 321 ? 187.542 198.230 192.621 1.00 32.40  ? 321 GLY B O   1 
ATOM   4111 N N   . PHE B 1 322 ? 186.548 197.400 194.456 1.00 26.12  ? 322 PHE B N   1 
ATOM   4112 C CA  . PHE B 1 322 ? 186.086 196.209 193.747 1.00 21.75  ? 322 PHE B CA  1 
ATOM   4113 C C   . PHE B 1 322 ? 185.069 196.563 192.666 1.00 36.92  ? 322 PHE B C   1 
ATOM   4114 O O   . PHE B 1 322 ? 185.135 196.045 191.541 1.00 54.18  ? 322 PHE B O   1 
ATOM   4115 C CB  . PHE B 1 322 ? 185.491 195.209 194.736 1.00 21.56  ? 322 PHE B CB  1 
ATOM   4116 C CG  . PHE B 1 322 ? 184.717 194.101 194.086 1.00 28.03  ? 322 PHE B CG  1 
ATOM   4117 C CD1 . PHE B 1 322 ? 185.346 193.202 193.242 1.00 38.76  ? 322 PHE B CD1 1 
ATOM   4118 C CD2 . PHE B 1 322 ? 183.360 193.958 194.318 1.00 27.46  ? 322 PHE B CD2 1 
ATOM   4119 C CE1 . PHE B 1 322 ? 184.636 192.180 192.643 1.00 41.68  ? 322 PHE B CE1 1 
ATOM   4120 C CE2 . PHE B 1 322 ? 182.645 192.938 193.721 1.00 31.43  ? 322 PHE B CE2 1 
ATOM   4121 C CZ  . PHE B 1 322 ? 183.284 192.049 192.882 1.00 39.95  ? 322 PHE B CZ  1 
ATOM   4122 N N   . LEU B 1 323 ? 184.119 197.444 192.986 1.00 42.13  ? 323 LEU B N   1 
ATOM   4123 C CA  . LEU B 1 323 ? 183.152 197.857 191.978 1.00 43.36  ? 323 LEU B CA  1 
ATOM   4124 C C   . LEU B 1 323 ? 183.822 198.632 190.849 1.00 40.06  ? 323 LEU B C   1 
ATOM   4125 O O   . LEU B 1 323 ? 183.412 198.513 189.689 1.00 45.72  ? 323 LEU B O   1 
ATOM   4126 C CB  . LEU B 1 323 ? 182.041 198.675 192.629 1.00 45.44  ? 323 LEU B CB  1 
ATOM   4127 C CG  . LEU B 1 323 ? 181.066 197.892 193.509 1.00 52.01  ? 323 LEU B CG  1 
ATOM   4128 C CD1 . LEU B 1 323 ? 180.006 198.814 194.088 1.00 49.75  ? 323 LEU B CD1 1 
ATOM   4129 C CD2 . LEU B 1 323 ? 180.427 196.765 192.715 1.00 48.86  ? 323 LEU B CD2 1 
ATOM   4130 N N   . GLY B 1 324 ? 184.862 199.409 191.159 1.00 38.42  ? 324 GLY B N   1 
ATOM   4131 C CA  . GLY B 1 324 ? 185.631 200.052 190.109 1.00 33.50  ? 324 GLY B CA  1 
ATOM   4132 C C   . GLY B 1 324 ? 186.386 199.057 189.251 1.00 39.54  ? 324 GLY B C   1 
ATOM   4133 O O   . GLY B 1 324 ? 186.547 199.263 188.047 1.00 41.81  ? 324 GLY B O   1 
ATOM   4134 N N   . ILE B 1 325 ? 186.868 197.970 189.858 1.00 39.08  ? 325 ILE B N   1 
ATOM   4135 C CA  . ILE B 1 325 ? 187.490 196.898 189.084 1.00 37.68  ? 325 ILE B CA  1 
ATOM   4136 C C   . ILE B 1 325 ? 186.493 196.344 188.081 1.00 39.40  ? 325 ILE B C   1 
ATOM   4137 O O   . ILE B 1 325 ? 186.801 196.169 186.895 1.00 47.25  ? 325 ILE B O   1 
ATOM   4138 C CB  . ILE B 1 325 ? 188.008 195.782 190.012 1.00 36.31  ? 325 ILE B CB  1 
ATOM   4139 C CG1 . ILE B 1 325 ? 189.119 196.285 190.930 1.00 39.61  ? 325 ILE B CG1 1 
ATOM   4140 C CG2 . ILE B 1 325 ? 188.497 194.595 189.197 1.00 32.88  ? 325 ILE B CG2 1 
ATOM   4141 C CD1 . ILE B 1 325 ? 189.996 197.308 190.306 1.00 37.82  ? 325 ILE B CD1 1 
ATOM   4142 N N   . LEU B 1 326 ? 185.276 196.064 188.550 1.00 30.51  ? 326 LEU B N   1 
ATOM   4143 C CA  . LEU B 1 326 ? 184.243 195.543 187.660 1.00 31.44  ? 326 LEU B CA  1 
ATOM   4144 C C   . LEU B 1 326 ? 183.918 196.535 186.549 1.00 37.55  ? 326 LEU B C   1 
ATOM   4145 O O   . LEU B 1 326 ? 183.793 196.152 185.378 1.00 42.55  ? 326 LEU B O   1 
ATOM   4146 C CB  . LEU B 1 326 ? 182.989 195.203 188.461 1.00 25.69  ? 326 LEU B CB  1 
ATOM   4147 C CG  . LEU B 1 326 ? 183.087 193.943 189.319 1.00 35.51  ? 326 LEU B CG  1 
ATOM   4148 C CD1 . LEU B 1 326 ? 181.746 193.632 189.954 1.00 42.09  ? 326 LEU B CD1 1 
ATOM   4149 C CD2 . LEU B 1 326 ? 183.576 192.768 188.488 1.00 32.81  ? 326 LEU B CD2 1 
ATOM   4150 N N   . TRP B 1 327 ? 183.787 197.817 186.897 1.00 36.14  ? 327 TRP B N   1 
ATOM   4151 C CA  . TRP B 1 327 ? 183.455 198.836 185.905 1.00 24.96  ? 327 TRP B CA  1 
ATOM   4152 C C   . TRP B 1 327 ? 184.554 198.964 184.855 1.00 33.22  ? 327 TRP B C   1 
ATOM   4153 O O   . TRP B 1 327 ? 184.275 199.049 183.654 1.00 46.95  ? 327 TRP B O   1 
ATOM   4154 C CB  . TRP B 1 327 ? 183.212 200.174 186.602 1.00 30.91  ? 327 TRP B CB  1 
ATOM   4155 C CG  . TRP B 1 327 ? 182.969 201.317 185.670 1.00 23.90  ? 327 TRP B CG  1 
ATOM   4156 C CD1 . TRP B 1 327 ? 181.816 201.595 184.998 1.00 34.09  ? 327 TRP B CD1 1 
ATOM   4157 C CD2 . TRP B 1 327 ? 183.900 202.344 185.311 1.00 27.23  ? 327 TRP B CD2 1 
ATOM   4158 N NE1 . TRP B 1 327 ? 181.971 202.730 184.242 1.00 42.26  ? 327 TRP B NE1 1 
ATOM   4159 C CE2 . TRP B 1 327 ? 183.243 203.208 184.415 1.00 38.35  ? 327 TRP B CE2 1 
ATOM   4160 C CE3 . TRP B 1 327 ? 185.226 202.615 185.658 1.00 30.85  ? 327 TRP B CE3 1 
ATOM   4161 C CZ2 . TRP B 1 327 ? 183.866 204.324 183.862 1.00 34.49  ? 327 TRP B CZ2 1 
ATOM   4162 C CZ3 . TRP B 1 327 ? 185.843 203.723 185.108 1.00 25.54  ? 327 TRP B CZ3 1 
ATOM   4163 C CH2 . TRP B 1 327 ? 185.163 204.564 184.221 1.00 24.61  ? 327 TRP B CH2 1 
ATOM   4164 N N   . CYS B 1 328 ? 185.815 198.982 185.294 1.00 33.65  ? 328 CYS B N   1 
ATOM   4165 C CA  . CYS B 1 328 ? 186.926 199.111 184.359 1.00 34.89  ? 328 CYS B CA  1 
ATOM   4166 C C   . CYS B 1 328 ? 187.042 197.885 183.465 1.00 40.32  ? 328 CYS B C   1 
ATOM   4167 O O   . CYS B 1 328 ? 187.329 198.011 182.270 1.00 40.84  ? 328 CYS B O   1 
ATOM   4168 C CB  . CYS B 1 328 ? 188.229 199.349 185.120 1.00 33.28  ? 328 CYS B CB  1 
ATOM   4169 S SG  . CYS B 1 328 ? 188.606 201.090 185.422 1.00 29.41  ? 328 CYS B SG  1 
ATOM   4170 N N   . LEU B 1 329 ? 186.828 196.690 184.022 1.00 52.88  ? 329 LEU B N   1 
ATOM   4171 C CA  . LEU B 1 329 ? 186.854 195.487 183.198 1.00 50.74  ? 329 LEU B CA  1 
ATOM   4172 C C   . LEU B 1 329 ? 185.742 195.512 182.158 1.00 50.52  ? 329 LEU B C   1 
ATOM   4173 O O   . LEU B 1 329 ? 185.963 195.155 180.994 1.00 56.27  ? 329 LEU B O   1 
ATOM   4174 C CB  . LEU B 1 329 ? 186.742 194.243 184.079 1.00 42.05  ? 329 LEU B CB  1 
ATOM   4175 C CG  . LEU B 1 329 ? 188.000 193.856 184.858 1.00 29.90  ? 329 LEU B CG  1 
ATOM   4176 C CD1 . LEU B 1 329 ? 187.787 192.549 185.604 1.00 42.61  ? 329 LEU B CD1 1 
ATOM   4177 C CD2 . LEU B 1 329 ? 189.197 193.759 183.929 1.00 46.76  ? 329 LEU B CD2 1 
ATOM   4178 N N   . SER B 1 330 ? 184.541 195.941 182.556 1.00 40.55  ? 330 SER B N   1 
ATOM   4179 C CA  . SER B 1 330 ? 183.439 196.027 181.603 1.00 47.35  ? 330 SER B CA  1 
ATOM   4180 C C   . SER B 1 330 ? 183.735 197.042 180.506 1.00 51.81  ? 330 SER B C   1 
ATOM   4181 O O   . SER B 1 330 ? 183.465 196.789 179.327 1.00 55.65  ? 330 SER B O   1 
ATOM   4182 C CB  . SER B 1 330 ? 182.144 196.386 182.330 1.00 53.89  ? 330 SER B CB  1 
ATOM   4183 O OG  . SER B 1 330 ? 181.044 196.384 181.437 1.00 59.64  ? 330 SER B OG  1 
ATOM   4184 N N   . LEU B 1 331 ? 184.296 198.197 180.873 1.00 41.13  ? 331 LEU B N   1 
ATOM   4185 C CA  . LEU B 1 331 ? 184.618 199.208 179.871 1.00 42.81  ? 331 LEU B CA  1 
ATOM   4186 C C   . LEU B 1 331 ? 185.707 198.722 178.920 1.00 53.06  ? 331 LEU B C   1 
ATOM   4187 O O   . LEU B 1 331 ? 185.633 198.965 177.709 1.00 51.16  ? 331 LEU B O   1 
ATOM   4188 C CB  . LEU B 1 331 ? 185.032 200.512 180.551 1.00 37.87  ? 331 LEU B CB  1 
ATOM   4189 C CG  . LEU B 1 331 ? 184.843 201.780 179.716 1.00 44.02  ? 331 LEU B CG  1 
ATOM   4190 C CD1 . LEU B 1 331 ? 183.544 201.713 178.931 1.00 50.55  ? 331 LEU B CD1 1 
ATOM   4191 C CD2 . LEU B 1 331 ? 184.864 203.016 180.598 1.00 46.59  ? 331 LEU B CD2 1 
ATOM   4192 N N   . LEU B 1 332 ? 186.727 198.040 179.448 1.00 52.69  ? 332 LEU B N   1 
ATOM   4193 C CA  . LEU B 1 332 ? 187.772 197.487 178.591 1.00 48.22  ? 332 LEU B CA  1 
ATOM   4194 C C   . LEU B 1 332 ? 187.207 196.446 177.635 1.00 50.68  ? 332 LEU B C   1 
ATOM   4195 O O   . LEU B 1 332 ? 187.570 196.417 176.453 1.00 61.60  ? 332 LEU B O   1 
ATOM   4196 C CB  . LEU B 1 332 ? 188.886 196.879 179.442 1.00 54.43  ? 332 LEU B CB  1 
ATOM   4197 C CG  . LEU B 1 332 ? 190.159 197.708 179.616 1.00 53.07  ? 332 LEU B CG  1 
ATOM   4198 C CD1 . LEU B 1 332 ? 191.240 196.885 180.288 1.00 52.54  ? 332 LEU B CD1 1 
ATOM   4199 C CD2 . LEU B 1 332 ? 190.643 198.232 178.276 1.00 53.92  ? 332 LEU B CD2 1 
ATOM   4200 N N   . ALA B 1 333 ? 186.321 195.578 178.128 1.00 52.53  ? 333 ALA B N   1 
ATOM   4201 C CA  . ALA B 1 333 ? 185.695 194.590 177.257 1.00 59.91  ? 333 ALA B CA  1 
ATOM   4202 C C   . ALA B 1 333 ? 184.840 195.263 176.190 1.00 68.20  ? 333 ALA B C   1 
ATOM   4203 O O   . ALA B 1 333 ? 184.779 194.798 175.046 1.00 75.24  ? 333 ALA B O   1 
ATOM   4204 C CB  . ALA B 1 333 ? 184.860 193.616 178.085 1.00 60.53  ? 333 ALA B CB  1 
ATOM   4205 N N   . CYS B 1 334 ? 184.166 196.357 176.550 1.00 69.19  ? 334 CYS B N   1 
ATOM   4206 C CA  . CYS B 1 334 ? 183.365 197.092 175.577 1.00 71.00  ? 334 CYS B CA  1 
ATOM   4207 C C   . CYS B 1 334 ? 184.239 197.747 174.515 1.00 70.82  ? 334 CYS B C   1 
ATOM   4208 O O   . CYS B 1 334 ? 183.845 197.830 173.345 1.00 70.81  ? 334 CYS B O   1 
ATOM   4209 C CB  . CYS B 1 334 ? 182.515 198.143 176.287 1.00 69.66  ? 334 CYS B CB  1 
ATOM   4210 S SG  . CYS B 1 334 ? 180.806 197.652 176.573 1.00 84.03  ? 334 CYS B SG  1 
ATOM   4211 N N   . PHE B 1 335 ? 185.421 198.230 174.905 1.00 61.73  ? 335 PHE B N   1 
ATOM   4212 C CA  . PHE B 1 335 ? 186.294 198.913 173.955 1.00 60.72  ? 335 PHE B CA  1 
ATOM   4213 C C   . PHE B 1 335 ? 186.729 197.974 172.836 1.00 64.74  ? 335 PHE B C   1 
ATOM   4214 O O   . PHE B 1 335 ? 186.596 198.297 171.650 1.00 66.93  ? 335 PHE B O   1 
ATOM   4215 C CB  . PHE B 1 335 ? 187.507 199.489 174.684 1.00 59.94  ? 335 PHE B CB  1 
ATOM   4216 C CG  . PHE B 1 335 ? 187.412 200.964 174.938 1.00 57.45  ? 335 PHE B CG  1 
ATOM   4217 C CD1 . PHE B 1 335 ? 186.648 201.451 175.985 1.00 57.18  ? 335 PHE B CD1 1 
ATOM   4218 C CD2 . PHE B 1 335 ? 188.082 201.865 174.130 1.00 59.78  ? 335 PHE B CD2 1 
ATOM   4219 C CE1 . PHE B 1 335 ? 186.557 202.807 176.223 1.00 58.04  ? 335 PHE B CE1 1 
ATOM   4220 C CE2 . PHE B 1 335 ? 187.993 203.222 174.362 1.00 60.89  ? 335 PHE B CE2 1 
ATOM   4221 C CZ  . PHE B 1 335 ? 187.230 203.694 175.411 1.00 60.96  ? 335 PHE B CZ  1 
ATOM   4222 N N   . PHE B 1 336 ? 187.254 196.805 173.195 1.00 68.52  ? 336 PHE B N   1 
ATOM   4223 C CA  . PHE B 1 336 ? 187.548 195.745 172.236 1.00 69.00  ? 336 PHE B CA  1 
ATOM   4224 C C   . PHE B 1 336 ? 187.020 194.435 172.799 1.00 70.58  ? 336 PHE B C   1 
ATOM   4225 O O   . PHE B 1 336 ? 187.393 194.038 173.907 1.00 67.91  ? 336 PHE B O   1 
ATOM   4226 C CB  . PHE B 1 336 ? 189.049 195.651 171.936 1.00 68.36  ? 336 PHE B CB  1 
ATOM   4227 C CG  . PHE B 1 336 ? 189.934 196.063 173.080 1.00 66.57  ? 336 PHE B CG  1 
ATOM   4228 C CD1 . PHE B 1 336 ? 190.154 195.212 174.150 1.00 65.34  ? 336 PHE B CD1 1 
ATOM   4229 C CD2 . PHE B 1 336 ? 190.557 197.299 173.077 1.00 65.54  ? 336 PHE B CD2 1 
ATOM   4230 C CE1 . PHE B 1 336 ? 190.971 195.590 175.197 1.00 66.43  ? 336 PHE B CE1 1 
ATOM   4231 C CE2 . PHE B 1 336 ? 191.376 197.681 174.122 1.00 66.56  ? 336 PHE B CE2 1 
ATOM   4232 C CZ  . PHE B 1 336 ? 191.583 196.825 175.182 1.00 66.15  ? 336 PHE B CZ  1 
ATOM   4233 N N   . ALA B 1 337 ? 186.150 193.778 172.047 1.00 86.39  ? 337 ALA B N   1 
ATOM   4234 C CA  . ALA B 1 337 ? 185.518 192.558 172.532 1.00 87.24  ? 337 ALA B CA  1 
ATOM   4235 C C   . ALA B 1 337 ? 186.523 191.414 172.551 1.00 87.08  ? 337 ALA B C   1 
ATOM   4236 O O   . ALA B 1 337 ? 187.066 191.062 171.496 1.00 86.39  ? 337 ALA B O   1 
ATOM   4237 C CB  . ALA B 1 337 ? 184.322 192.197 171.658 1.00 85.61  ? 337 ALA B CB  1 
ATOM   4238 N N   . PRO B 1 338 ? 186.810 190.818 173.712 1.00 93.41  ? 338 PRO B N   1 
ATOM   4239 C CA  . PRO B 1 338 ? 187.695 189.642 173.717 1.00 94.92  ? 338 PRO B CA  1 
ATOM   4240 C C   . PRO B 1 338 ? 187.109 188.459 172.970 1.00 94.18  ? 338 PRO B C   1 
ATOM   4241 O O   . PRO B 1 338 ? 187.858 187.675 172.374 1.00 92.74  ? 338 PRO B O   1 
ATOM   4242 C CB  . PRO B 1 338 ? 187.879 189.342 175.214 1.00 93.92  ? 338 PRO B CB  1 
ATOM   4243 C CG  . PRO B 1 338 ? 187.371 190.559 175.937 1.00 92.97  ? 338 PRO B CG  1 
ATOM   4244 C CD  . PRO B 1 338 ? 186.323 191.152 175.059 1.00 92.29  ? 338 PRO B CD  1 
ATOM   4245 N N   . ILE B 1 339 ? 185.788 188.307 172.985 1.00 99.23  ? 339 ILE B N   1 
ATOM   4246 C CA  . ILE B 1 339 ? 185.105 187.190 172.344 1.00 98.17  ? 339 ILE B CA  1 
ATOM   4247 C C   . ILE B 1 339 ? 184.218 187.749 171.241 1.00 101.02 ? 339 ILE B C   1 
ATOM   4248 O O   . ILE B 1 339 ? 183.391 188.636 171.488 1.00 100.40 ? 339 ILE B O   1 
ATOM   4249 C CB  . ILE B 1 339 ? 184.281 186.373 173.352 1.00 95.92  ? 339 ILE B CB  1 
ATOM   4250 C CG1 . ILE B 1 339 ? 185.195 185.724 174.394 1.00 95.96  ? 339 ILE B CG1 1 
ATOM   4251 C CG2 . ILE B 1 339 ? 183.455 185.318 172.633 1.00 95.97  ? 339 ILE B CG2 1 
ATOM   4252 C CD1 . ILE B 1 339 ? 185.332 186.518 175.676 1.00 95.53  ? 339 ILE B CD1 1 
ATOM   4253 N N   . SER B 1 340 ? 184.393 187.233 170.022 1.00 107.69 ? 340 SER B N   1 
ATOM   4254 C CA  . SER B 1 340 ? 183.564 187.676 168.906 1.00 106.53 ? 340 SER B CA  1 
ATOM   4255 C C   . SER B 1 340 ? 182.112 187.247 169.078 1.00 107.40 ? 340 SER B C   1 
ATOM   4256 O O   . SER B 1 340 ? 181.201 187.968 168.655 1.00 105.76 ? 340 SER B O   1 
ATOM   4257 C CB  . SER B 1 340 ? 184.124 187.138 167.590 1.00 105.23 ? 340 SER B CB  1 
ATOM   4258 O OG  . SER B 1 340 ? 185.482 187.504 167.426 1.00 105.80 ? 340 SER B OG  1 
ATOM   4259 N N   . VAL B 1 341 ? 181.879 186.080 169.683 1.00 110.29 ? 341 VAL B N   1 
ATOM   4260 C CA  . VAL B 1 341 ? 180.514 185.598 169.878 1.00 110.74 ? 341 VAL B CA  1 
ATOM   4261 C C   . VAL B 1 341 ? 179.750 186.516 170.823 1.00 111.08 ? 341 VAL B C   1 
ATOM   4262 O O   . VAL B 1 341 ? 178.585 186.855 170.578 1.00 109.47 ? 341 VAL B O   1 
ATOM   4263 C CB  . VAL B 1 341 ? 180.530 184.146 170.389 1.00 108.80 ? 341 VAL B CB  1 
ATOM   4264 C CG1 . VAL B 1 341 ? 179.110 183.632 170.578 1.00 110.25 ? 341 VAL B CG1 1 
ATOM   4265 C CG2 . VAL B 1 341 ? 181.302 183.254 169.430 1.00 107.30 ? 341 VAL B CG2 1 
ATOM   4266 N N   . ILE B 1 342 ? 180.387 186.934 171.913 1.00 108.83 ? 342 ILE B N   1 
ATOM   4267 C CA  . ILE B 1 342 ? 179.740 187.776 172.915 1.00 107.06 ? 342 ILE B CA  1 
ATOM   4268 C C   . ILE B 1 342 ? 179.576 189.187 172.361 1.00 107.45 ? 342 ILE B C   1 
ATOM   4269 O O   . ILE B 1 342 ? 180.571 189.827 171.991 1.00 105.86 ? 342 ILE B O   1 
ATOM   4270 C CB  . ILE B 1 342 ? 180.537 187.791 174.229 1.00 104.75 ? 342 ILE B CB  1 
ATOM   4271 C CG1 . ILE B 1 342 ? 180.662 186.375 174.793 1.00 104.86 ? 342 ILE B CG1 1 
ATOM   4272 C CG2 . ILE B 1 342 ? 179.876 188.711 175.241 1.00 104.57 ? 342 ILE B CG2 1 
ATOM   4273 C CD1 . ILE B 1 342 ? 181.515 186.289 176.039 1.00 105.99 ? 342 ILE B CD1 1 
ATOM   4274 N N   . PRO B 1 343 ? 178.354 189.707 172.284 1.00 111.77 ? 343 PRO B N   1 
ATOM   4275 C CA  . PRO B 1 343 ? 178.163 191.080 171.809 1.00 111.15 ? 343 PRO B CA  1 
ATOM   4276 C C   . PRO B 1 343 ? 178.716 192.092 172.799 1.00 108.44 ? 343 PRO B C   1 
ATOM   4277 O O   . PRO B 1 343 ? 178.830 191.838 174.000 1.00 106.77 ? 343 PRO B O   1 
ATOM   4278 C CB  . PRO B 1 343 ? 176.640 191.209 171.678 1.00 108.45 ? 343 PRO B CB  1 
ATOM   4279 C CG  . PRO B 1 343 ? 176.118 189.799 171.701 1.00 108.40 ? 343 PRO B CG  1 
ATOM   4280 C CD  . PRO B 1 343 ? 177.074 189.035 172.556 1.00 109.71 ? 343 PRO B CD  1 
ATOM   4281 N N   . THR B 1 344 ? 179.070 193.262 172.269 1.00 103.16 ? 344 THR B N   1 
ATOM   4282 C CA  . THR B 1 344 ? 179.601 194.335 173.099 1.00 101.96 ? 344 THR B CA  1 
ATOM   4283 C C   . THR B 1 344 ? 178.524 195.069 173.887 1.00 104.54 ? 344 THR B C   1 
ATOM   4284 O O   . THR B 1 344 ? 178.862 195.845 174.787 1.00 105.79 ? 344 THR B O   1 
ATOM   4285 C CB  . THR B 1 344 ? 180.371 195.340 172.238 1.00 102.85 ? 344 THR B CB  1 
ATOM   4286 O OG1 . THR B 1 344 ? 179.726 195.475 170.965 1.00 106.84 ? 344 THR B OG1 1 
ATOM   4287 C CG2 . THR B 1 344 ? 181.802 194.875 172.030 1.00 103.00 ? 344 THR B CG2 1 
ATOM   4288 N N   . TYR B 1 345 ? 177.248 194.846 173.581 1.00 111.27 ? 345 TYR B N   1 
ATOM   4289 C CA  . TYR B 1 345 ? 176.158 195.530 174.262 1.00 111.54 ? 345 TYR B CA  1 
ATOM   4290 C C   . TYR B 1 345 ? 175.707 194.829 175.538 1.00 110.08 ? 345 TYR B C   1 
ATOM   4291 O O   . TYR B 1 345 ? 174.835 195.353 176.238 1.00 110.79 ? 345 TYR B O   1 
ATOM   4292 C CB  . TYR B 1 345 ? 174.979 195.730 173.288 1.00 111.30 ? 345 TYR B CB  1 
ATOM   4293 C CG  . TYR B 1 345 ? 174.222 194.484 172.834 1.00 112.71 ? 345 TYR B CG  1 
ATOM   4294 C CD1 . TYR B 1 345 ? 173.661 193.590 173.741 1.00 112.36 ? 345 TYR B CD1 1 
ATOM   4295 C CD2 . TYR B 1 345 ? 174.074 194.211 171.480 1.00 111.44 ? 345 TYR B CD2 1 
ATOM   4296 C CE1 . TYR B 1 345 ? 172.980 192.468 173.315 1.00 114.06 ? 345 TYR B CE1 1 
ATOM   4297 C CE2 . TYR B 1 345 ? 173.393 193.090 171.045 1.00 111.51 ? 345 TYR B CE2 1 
ATOM   4298 C CZ  . TYR B 1 345 ? 172.849 192.223 171.966 1.00 113.90 ? 345 TYR B CZ  1 
ATOM   4299 O OH  . TYR B 1 345 ? 172.170 191.106 171.537 1.00 111.80 ? 345 TYR B OH  1 
ATOM   4300 N N   . VAL B 1 346 ? 176.268 193.661 175.853 1.00 94.93  ? 346 VAL B N   1 
ATOM   4301 C CA  . VAL B 1 346 ? 175.899 192.964 177.080 1.00 95.86  ? 346 VAL B CA  1 
ATOM   4302 C C   . VAL B 1 346 ? 176.859 193.275 178.224 1.00 95.18  ? 346 VAL B C   1 
ATOM   4303 O O   . VAL B 1 346 ? 176.495 193.091 179.395 1.00 91.96  ? 346 VAL B O   1 
ATOM   4304 C CB  . VAL B 1 346 ? 175.825 191.443 176.838 1.00 95.80  ? 346 VAL B CB  1 
ATOM   4305 C CG1 . VAL B 1 346 ? 177.211 190.867 176.599 1.00 94.39  ? 346 VAL B CG1 1 
ATOM   4306 C CG2 . VAL B 1 346 ? 175.117 190.733 177.989 1.00 93.51  ? 346 VAL B CG2 1 
ATOM   4307 N N   . TYR B 1 347 ? 178.067 193.755 177.922 1.00 87.86  ? 347 TYR B N   1 
ATOM   4308 C CA  . TYR B 1 347 ? 179.025 194.083 178.975 1.00 86.96  ? 347 TYR B CA  1 
ATOM   4309 C C   . TYR B 1 347 ? 178.506 195.134 179.950 1.00 85.34  ? 347 TYR B C   1 
ATOM   4310 O O   . TYR B 1 347 ? 178.634 194.923 181.168 1.00 84.93  ? 347 TYR B O   1 
ATOM   4311 C CB  . TYR B 1 347 ? 180.355 194.508 178.343 1.00 83.49  ? 347 TYR B CB  1 
ATOM   4312 C CG  . TYR B 1 347 ? 181.069 193.385 177.628 1.00 84.30  ? 347 TYR B CG  1 
ATOM   4313 C CD1 . TYR B 1 347 ? 181.080 192.100 178.152 1.00 83.80  ? 347 TYR B CD1 1 
ATOM   4314 C CD2 . TYR B 1 347 ? 181.725 193.608 176.425 1.00 86.29  ? 347 TYR B CD2 1 
ATOM   4315 C CE1 . TYR B 1 347 ? 181.730 191.070 177.502 1.00 85.84  ? 347 TYR B CE1 1 
ATOM   4316 C CE2 . TYR B 1 347 ? 182.377 192.583 175.767 1.00 89.63  ? 347 TYR B CE2 1 
ATOM   4317 C CZ  . TYR B 1 347 ? 182.376 191.317 176.311 1.00 88.95  ? 347 TYR B CZ  1 
ATOM   4318 O OH  . TYR B 1 347 ? 183.024 190.293 175.659 1.00 90.95  ? 347 TYR B OH  1 
ATOM   4319 N N   . PRO B 1 348 ? 177.939 196.271 179.517 1.00 77.65  ? 348 PRO B N   1 
ATOM   4320 C CA  . PRO B 1 348 ? 177.308 197.161 180.507 1.00 73.46  ? 348 PRO B CA  1 
ATOM   4321 C C   . PRO B 1 348 ? 176.149 196.497 181.225 1.00 79.44  ? 348 PRO B C   1 
ATOM   4322 O O   . PRO B 1 348 ? 175.976 196.682 182.438 1.00 88.43  ? 348 PRO B O   1 
ATOM   4323 C CB  . PRO B 1 348 ? 176.847 198.364 179.671 1.00 70.85  ? 348 PRO B CB  1 
ATOM   4324 C CG  . PRO B 1 348 ? 177.511 198.229 178.351 1.00 78.78  ? 348 PRO B CG  1 
ATOM   4325 C CD  . PRO B 1 348 ? 177.779 196.783 178.145 1.00 80.43  ? 348 PRO B CD  1 
ATOM   4326 N N   . LEU B 1 349 ? 175.353 195.711 180.496 1.00 77.55  ? 349 LEU B N   1 
ATOM   4327 C CA  . LEU B 1 349 ? 174.262 194.975 181.121 1.00 82.67  ? 349 LEU B CA  1 
ATOM   4328 C C   . LEU B 1 349 ? 174.803 193.994 182.150 1.00 82.11  ? 349 LEU B C   1 
ATOM   4329 O O   . LEU B 1 349 ? 174.264 193.887 183.256 1.00 82.75  ? 349 LEU B O   1 
ATOM   4330 C CB  . LEU B 1 349 ? 173.441 194.256 180.046 1.00 81.04  ? 349 LEU B CB  1 
ATOM   4331 C CG  . LEU B 1 349 ? 171.988 193.799 180.259 1.00 82.01  ? 349 LEU B CG  1 
ATOM   4332 C CD1 . LEU B 1 349 ? 171.525 192.996 179.052 1.00 84.35  ? 349 LEU B CD1 1 
ATOM   4333 C CD2 . LEU B 1 349 ? 171.762 192.995 181.534 1.00 81.58  ? 349 LEU B CD2 1 
ATOM   4334 N N   . ALA B 1 350 ? 175.881 193.284 181.811 1.00 72.23  ? 350 ALA B N   1 
ATOM   4335 C CA  . ALA B 1 350 ? 176.478 192.347 182.758 1.00 75.38  ? 350 ALA B CA  1 
ATOM   4336 C C   . ALA B 1 350 ? 177.007 193.067 183.991 1.00 80.06  ? 350 ALA B C   1 
ATOM   4337 O O   . ALA B 1 350 ? 176.817 192.599 185.119 1.00 82.22  ? 350 ALA B O   1 
ATOM   4338 C CB  . ALA B 1 350 ? 177.594 191.553 182.080 1.00 76.58  ? 350 ALA B CB  1 
ATOM   4339 N N   . LEU B 1 351 ? 177.670 194.210 183.799 1.00 73.67  ? 351 LEU B N   1 
ATOM   4340 C CA  . LEU B 1 351 ? 178.231 194.944 184.930 1.00 66.76  ? 351 LEU B CA  1 
ATOM   4341 C C   . LEU B 1 351 ? 177.135 195.438 185.866 1.00 62.82  ? 351 LEU B C   1 
ATOM   4342 O O   . LEU B 1 351 ? 177.224 195.273 187.089 1.00 67.72  ? 351 LEU B O   1 
ATOM   4343 C CB  . LEU B 1 351 ? 179.077 196.115 184.426 1.00 62.51  ? 351 LEU B CB  1 
ATOM   4344 C CG  . LEU B 1 351 ? 179.248 197.296 185.383 1.00 55.20  ? 351 LEU B CG  1 
ATOM   4345 C CD1 . LEU B 1 351 ? 180.240 196.956 186.483 1.00 57.85  ? 351 LEU B CD1 1 
ATOM   4346 C CD2 . LEU B 1 351 ? 179.686 198.542 184.632 1.00 59.50  ? 351 LEU B CD2 1 
ATOM   4347 N N   . TYR B 1 352 ? 176.082 196.040 185.309 1.00 61.26  ? 352 TYR B N   1 
ATOM   4348 C CA  . TYR B 1 352 ? 175.017 196.556 186.163 1.00 64.52  ? 352 TYR B CA  1 
ATOM   4349 C C   . TYR B 1 352 ? 174.195 195.434 186.784 1.00 71.91  ? 352 TYR B C   1 
ATOM   4350 O O   . TYR B 1 352 ? 173.727 195.572 187.921 1.00 77.80  ? 352 TYR B O   1 
ATOM   4351 C CB  . TYR B 1 352 ? 174.132 197.521 185.376 1.00 64.71  ? 352 TYR B CB  1 
ATOM   4352 C CG  . TYR B 1 352 ? 174.855 198.793 185.001 1.00 65.36  ? 352 TYR B CG  1 
ATOM   4353 C CD1 . TYR B 1 352 ? 175.530 199.534 185.961 1.00 63.96  ? 352 TYR B CD1 1 
ATOM   4354 C CD2 . TYR B 1 352 ? 174.872 199.249 183.692 1.00 71.93  ? 352 TYR B CD2 1 
ATOM   4355 C CE1 . TYR B 1 352 ? 176.198 200.695 185.628 1.00 71.69  ? 352 TYR B CE1 1 
ATOM   4356 C CE2 . TYR B 1 352 ? 175.537 200.409 183.349 1.00 73.79  ? 352 TYR B CE2 1 
ATOM   4357 C CZ  . TYR B 1 352 ? 176.198 201.128 184.321 1.00 76.49  ? 352 TYR B CZ  1 
ATOM   4358 O OH  . TYR B 1 352 ? 176.861 202.285 183.984 1.00 75.38  ? 352 TYR B OH  1 
ATOM   4359 N N   . GLY B 1 353 ? 174.020 194.317 186.077 1.00 68.86  ? 353 GLY B N   1 
ATOM   4360 C CA  . GLY B 1 353 ? 173.379 193.166 186.686 1.00 70.57  ? 353 GLY B CA  1 
ATOM   4361 C C   . GLY B 1 353 ? 174.184 192.603 187.839 1.00 72.66  ? 353 GLY B C   1 
ATOM   4362 O O   . GLY B 1 353 ? 173.626 192.227 188.870 1.00 73.61  ? 353 GLY B O   1 
ATOM   4363 N N   . PHE B 1 354 ? 175.509 192.543 187.684 1.00 71.23  ? 354 PHE B N   1 
ATOM   4364 C CA  . PHE B 1 354 ? 176.359 192.103 188.783 1.00 69.80  ? 354 PHE B CA  1 
ATOM   4365 C C   . PHE B 1 354 ? 176.268 193.064 189.960 1.00 73.20  ? 354 PHE B C   1 
ATOM   4366 O O   . PHE B 1 354 ? 176.236 192.636 191.117 1.00 74.20  ? 354 PHE B O   1 
ATOM   4367 C CB  . PHE B 1 354 ? 177.807 191.966 188.310 1.00 67.10  ? 354 PHE B CB  1 
ATOM   4368 C CG  . PHE B 1 354 ? 178.645 191.064 189.172 1.00 69.66  ? 354 PHE B CG  1 
ATOM   4369 C CD1 . PHE B 1 354 ? 179.066 191.472 190.427 1.00 71.60  ? 354 PHE B CD1 1 
ATOM   4370 C CD2 . PHE B 1 354 ? 179.013 189.806 188.726 1.00 75.06  ? 354 PHE B CD2 1 
ATOM   4371 C CE1 . PHE B 1 354 ? 179.837 190.643 191.220 1.00 76.76  ? 354 PHE B CE1 1 
ATOM   4372 C CE2 . PHE B 1 354 ? 179.783 188.972 189.514 1.00 74.68  ? 354 PHE B CE2 1 
ATOM   4373 C CZ  . PHE B 1 354 ? 180.196 189.391 190.763 1.00 77.30  ? 354 PHE B CZ  1 
ATOM   4374 N N   . MET B 1 355 ? 176.233 194.370 189.684 1.00 73.86  ? 355 MET B N   1 
ATOM   4375 C CA  . MET B 1 355 ? 176.100 195.349 190.759 1.00 69.29  ? 355 MET B CA  1 
ATOM   4376 C C   . MET B 1 355 ? 174.784 195.169 191.509 1.00 70.69  ? 355 MET B C   1 
ATOM   4377 O O   . MET B 1 355 ? 174.754 195.154 192.746 1.00 77.79  ? 355 MET B O   1 
ATOM   4378 C CB  . MET B 1 355 ? 176.205 196.765 190.192 1.00 62.98  ? 355 MET B CB  1 
ATOM   4379 C CG  . MET B 1 355 ? 177.544 197.437 190.432 1.00 65.25  ? 355 MET B CG  1 
ATOM   4380 S SD  . MET B 1 355 ? 177.660 199.039 189.613 1.00 79.41  ? 355 MET B SD  1 
ATOM   4381 C CE  . MET B 1 355 ? 179.430 199.300 189.626 1.00 60.23  ? 355 MET B CE  1 
ATOM   4382 N N   . VAL B 1 356 ? 173.682 195.016 190.771 1.00 71.74  ? 356 VAL B N   1 
ATOM   4383 C CA  . VAL B 1 356 ? 172.380 194.877 191.416 1.00 73.79  ? 356 VAL B CA  1 
ATOM   4384 C C   . VAL B 1 356 ? 172.291 193.551 192.165 1.00 77.04  ? 356 VAL B C   1 
ATOM   4385 O O   . VAL B 1 356 ? 171.667 193.470 193.229 1.00 74.80  ? 356 VAL B O   1 
ATOM   4386 C CB  . VAL B 1 356 ? 171.242 195.053 190.390 1.00 76.87  ? 356 VAL B CB  1 
ATOM   4387 C CG1 . VAL B 1 356 ? 170.915 193.750 189.673 1.00 76.25  ? 356 VAL B CG1 1 
ATOM   4388 C CG2 . VAL B 1 356 ? 170.001 195.615 191.070 1.00 76.75  ? 356 VAL B CG2 1 
ATOM   4389 N N   . PHE B 1 357 ? 172.921 192.496 191.636 1.00 86.62  ? 357 PHE B N   1 
ATOM   4390 C CA  . PHE B 1 357 ? 172.954 191.221 192.344 1.00 87.62  ? 357 PHE B CA  1 
ATOM   4391 C C   . PHE B 1 357 ? 173.763 191.334 193.627 1.00 87.34  ? 357 PHE B C   1 
ATOM   4392 O O   . PHE B 1 357 ? 173.374 190.788 194.664 1.00 85.79  ? 357 PHE B O   1 
ATOM   4393 C CB  . PHE B 1 357 ? 173.524 190.129 191.440 1.00 85.58  ? 357 PHE B CB  1 
ATOM   4394 C CG  . PHE B 1 357 ? 172.555 189.634 190.405 1.00 87.89  ? 357 PHE B CG  1 
ATOM   4395 C CD1 . PHE B 1 357 ? 171.192 189.648 190.652 1.00 89.03  ? 357 PHE B CD1 1 
ATOM   4396 C CD2 . PHE B 1 357 ? 173.006 189.156 189.186 1.00 86.38  ? 357 PHE B CD2 1 
ATOM   4397 C CE1 . PHE B 1 357 ? 170.297 189.195 189.703 1.00 88.08  ? 357 PHE B CE1 1 
ATOM   4398 C CE2 . PHE B 1 357 ? 172.115 188.701 188.233 1.00 87.25  ? 357 PHE B CE2 1 
ATOM   4399 C CZ  . PHE B 1 357 ? 170.759 188.720 188.492 1.00 87.52  ? 357 PHE B CZ  1 
ATOM   4400 N N   . PHE B 1 358 ? 174.893 192.042 193.574 1.00 81.24  ? 358 PHE B N   1 
ATOM   4401 C CA  . PHE B 1 358 ? 175.648 192.343 194.783 1.00 77.40  ? 358 PHE B CA  1 
ATOM   4402 C C   . PHE B 1 358 ? 174.786 193.081 195.794 1.00 77.65  ? 358 PHE B C   1 
ATOM   4403 O O   . PHE B 1 358 ? 174.865 192.806 196.995 1.00 74.92  ? 358 PHE B O   1 
ATOM   4404 C CB  . PHE B 1 358 ? 176.888 193.165 194.425 1.00 75.80  ? 358 PHE B CB  1 
ATOM   4405 C CG  . PHE B 1 358 ? 177.796 193.448 195.589 1.00 80.79  ? 358 PHE B CG  1 
ATOM   4406 C CD1 . PHE B 1 358 ? 178.816 192.572 195.918 1.00 83.71  ? 358 PHE B CD1 1 
ATOM   4407 C CD2 . PHE B 1 358 ? 177.638 194.598 196.347 1.00 79.94  ? 358 PHE B CD2 1 
ATOM   4408 C CE1 . PHE B 1 358 ? 179.656 192.832 196.985 1.00 83.47  ? 358 PHE B CE1 1 
ATOM   4409 C CE2 . PHE B 1 358 ? 178.474 194.863 197.414 1.00 78.55  ? 358 PHE B CE2 1 
ATOM   4410 C CZ  . PHE B 1 358 ? 179.484 193.979 197.733 1.00 81.26  ? 358 PHE B CZ  1 
ATOM   4411 N N   . LEU B 1 359 ? 173.946 194.003 195.328 1.00 83.01  ? 359 LEU B N   1 
ATOM   4412 C CA  . LEU B 1 359 ? 173.061 194.742 196.217 1.00 81.35  ? 359 LEU B CA  1 
ATOM   4413 C C   . LEU B 1 359 ? 171.939 193.890 196.799 1.00 83.65  ? 359 LEU B C   1 
ATOM   4414 O O   . LEU B 1 359 ? 171.512 194.147 197.931 1.00 81.88  ? 359 LEU B O   1 
ATOM   4415 C CB  . LEU B 1 359 ? 172.459 195.941 195.478 1.00 80.58  ? 359 LEU B CB  1 
ATOM   4416 C CG  . LEU B 1 359 ? 171.692 196.951 196.331 1.00 81.55  ? 359 LEU B CG  1 
ATOM   4417 C CD1 . LEU B 1 359 ? 172.632 197.642 197.300 1.00 78.10  ? 359 LEU B CD1 1 
ATOM   4418 C CD2 . LEU B 1 359 ? 170.980 197.968 195.453 1.00 87.68  ? 359 LEU B CD2 1 
ATOM   4419 N N   . ILE B 1 360 ? 171.459 192.882 196.069 1.00 93.44  ? 360 ILE B N   1 
ATOM   4420 C CA  . ILE B 1 360 ? 170.307 192.087 196.485 1.00 92.56  ? 360 ILE B CA  1 
ATOM   4421 C C   . ILE B 1 360 ? 170.711 190.707 196.991 1.00 94.14  ? 360 ILE B C   1 
ATOM   4422 O O   . ILE B 1 360 ? 169.857 189.971 197.507 1.00 96.19  ? 360 ILE B O   1 
ATOM   4423 C CB  . ILE B 1 360 ? 169.282 191.970 195.336 1.00 90.69  ? 360 ILE B CB  1 
ATOM   4424 C CG1 . ILE B 1 360 ? 167.968 191.326 195.787 1.00 91.07  ? 360 ILE B CG1 1 
ATOM   4425 C CG2 . ILE B 1 360 ? 169.851 191.138 194.205 1.00 89.11  ? 360 ILE B CG2 1 
ATOM   4426 C CD1 . ILE B 1 360 ? 167.198 192.144 196.795 1.00 89.81  ? 360 ILE B CD1 1 
ATOM   4427 N N   . ASN B 1 361 ? 171.999 190.348 196.895 1.00 97.48  ? 361 ASN B N   1 
ATOM   4428 C CA  . ASN B 1 361 ? 172.522 189.012 197.180 1.00 97.42  ? 361 ASN B CA  1 
ATOM   4429 C C   . ASN B 1 361 ? 172.026 188.578 198.555 1.00 99.74  ? 361 ASN B C   1 
ATOM   4430 O O   . ASN B 1 361 ? 172.400 189.177 199.571 1.00 98.17  ? 361 ASN B O   1 
ATOM   4431 C CB  . ASN B 1 361 ? 174.059 189.031 197.082 1.00 95.92  ? 361 ASN B CB  1 
ATOM   4432 C CG  . ASN B 1 361 ? 174.754 187.826 197.740 1.00 98.67  ? 361 ASN B CG  1 
ATOM   4433 O OD1 . ASN B 1 361 ? 174.191 187.092 198.547 1.00 99.23  ? 361 ASN B OD1 1 
ATOM   4434 N ND2 . ASN B 1 361 ? 176.015 187.633 197.372 1.00 99.82  ? 361 ASN B ND2 1 
ATOM   4435 N N   . PRO B 1 362 ? 171.185 187.542 198.625 1.00 100.42 ? 362 PRO B N   1 
ATOM   4436 C CA  . PRO B 1 362 ? 170.644 187.113 199.922 1.00 99.94  ? 362 PRO B CA  1 
ATOM   4437 C C   . PRO B 1 362 ? 171.642 186.320 200.750 1.00 97.57  ? 362 PRO B C   1 
ATOM   4438 O O   . PRO B 1 362 ? 171.548 186.289 201.981 1.00 94.51  ? 362 PRO B O   1 
ATOM   4439 C CB  . PRO B 1 362 ? 169.437 186.255 199.525 1.00 98.08  ? 362 PRO B CB  1 
ATOM   4440 C CG  . PRO B 1 362 ? 169.800 185.708 198.187 1.00 97.57  ? 362 PRO B CG  1 
ATOM   4441 C CD  . PRO B 1 362 ? 170.644 186.754 197.504 1.00 97.71  ? 362 PRO B CD  1 
ATOM   4442 N N   . THR B 1 363 ? 172.596 185.670 200.086 1.00 99.93  ? 363 THR B N   1 
ATOM   4443 C CA  . THR B 1 363 ? 173.598 184.879 200.789 1.00 100.82 ? 363 THR B CA  1 
ATOM   4444 C C   . THR B 1 363 ? 174.485 185.781 201.641 1.00 99.83  ? 363 THR B C   1 
ATOM   4445 O O   . THR B 1 363 ? 174.935 186.838 201.188 1.00 99.29  ? 363 THR B O   1 
ATOM   4446 C CB  . THR B 1 363 ? 174.441 184.086 199.792 1.00 102.56 ? 363 THR B CB  1 
ATOM   4447 O OG1 . THR B 1 363 ? 175.554 184.881 199.366 1.00 104.47 ? 363 THR B OG1 1 
ATOM   4448 C CG2 . THR B 1 363 ? 173.607 183.696 198.580 1.00 102.18 ? 363 THR B CG2 1 
ATOM   4449 N N   . LYS B 1 364 ? 174.737 185.358 202.879 1.00 100.54 ? 364 LYS B N   1 
ATOM   4450 C CA  . LYS B 1 364 ? 175.436 186.189 203.859 1.00 101.92 ? 364 LYS B CA  1 
ATOM   4451 C C   . LYS B 1 364 ? 176.948 185.985 203.747 1.00 101.66 ? 364 LYS B C   1 
ATOM   4452 O O   . LYS B 1 364 ? 177.599 185.376 204.598 1.00 103.49 ? 364 LYS B O   1 
ATOM   4453 C CB  . LYS B 1 364 ? 174.930 185.884 205.263 1.00 100.39 ? 364 LYS B CB  1 
ATOM   4454 C CG  . LYS B 1 364 ? 173.471 185.457 205.308 1.00 100.24 ? 364 LYS B CG  1 
ATOM   4455 C CD  . LYS B 1 364 ? 173.155 184.693 206.583 1.00 101.96 ? 364 LYS B CD  1 
ATOM   4456 C CE  . LYS B 1 364 ? 173.499 185.511 207.817 1.00 100.30 ? 364 LYS B CE  1 
ATOM   4457 N NZ  . LYS B 1 364 ? 172.480 185.353 208.890 1.00 100.74 ? 364 LYS B NZ  1 
ATOM   4458 N N   . THR B 1 365 ? 177.507 186.517 202.661 1.00 94.74  ? 365 THR B N   1 
ATOM   4459 C CA  . THR B 1 365 ? 178.947 186.478 202.434 1.00 97.17  ? 365 THR B CA  1 
ATOM   4460 C C   . THR B 1 365 ? 179.575 187.860 202.357 1.00 96.01  ? 365 THR B C   1 
ATOM   4461 O O   . THR B 1 365 ? 180.544 188.135 203.075 1.00 93.79  ? 365 THR B O   1 
ATOM   4462 C CB  . THR B 1 365 ? 179.268 185.693 201.150 1.00 96.95  ? 365 THR B CB  1 
ATOM   4463 O OG1 . THR B 1 365 ? 179.254 186.582 200.026 1.00 92.75  ? 365 THR B OG1 1 
ATOM   4464 C CG2 . THR B 1 365 ? 178.265 184.573 200.933 1.00 94.80  ? 365 THR B CG2 1 
ATOM   4465 N N   . PHE B 1 366 ? 179.052 188.744 201.508 1.00 87.57  ? 366 PHE B N   1 
ATOM   4466 C CA  . PHE B 1 366 ? 179.672 190.042 201.241 1.00 86.39  ? 366 PHE B CA  1 
ATOM   4467 C C   . PHE B 1 366 ? 178.895 191.128 201.979 1.00 86.32  ? 366 PHE B C   1 
ATOM   4468 O O   . PHE B 1 366 ? 177.891 191.641 201.484 1.00 84.48  ? 366 PHE B O   1 
ATOM   4469 C CB  . PHE B 1 366 ? 179.720 190.317 199.742 1.00 83.11  ? 366 PHE B CB  1 
ATOM   4470 C CG  . PHE B 1 366 ? 180.748 189.506 199.009 1.00 86.98  ? 366 PHE B CG  1 
ATOM   4471 C CD1 . PHE B 1 366 ? 182.076 189.528 199.400 1.00 88.55  ? 366 PHE B CD1 1 
ATOM   4472 C CD2 . PHE B 1 366 ? 180.387 188.724 197.924 1.00 87.40  ? 366 PHE B CD2 1 
ATOM   4473 C CE1 . PHE B 1 366 ? 183.024 188.784 198.725 1.00 85.14  ? 366 PHE B CE1 1 
ATOM   4474 C CE2 . PHE B 1 366 ? 181.331 187.977 197.246 1.00 86.62  ? 366 PHE B CE2 1 
ATOM   4475 C CZ  . PHE B 1 366 ? 182.651 188.008 197.647 1.00 83.36  ? 366 PHE B CZ  1 
ATOM   4476 N N   . TYR B 1 367 ? 179.379 191.486 203.169 1.00 81.31  ? 367 TYR B N   1 
ATOM   4477 C CA  . TYR B 1 367 ? 178.832 192.593 203.957 1.00 79.57  ? 367 TYR B CA  1 
ATOM   4478 C C   . TYR B 1 367 ? 177.322 192.455 204.136 1.00 77.80  ? 367 TYR B C   1 
ATOM   4479 O O   . TYR B 1 367 ? 176.553 193.383 203.878 1.00 79.91  ? 367 TYR B O   1 
ATOM   4480 C CB  . TYR B 1 367 ? 179.178 193.942 203.321 1.00 78.87  ? 367 TYR B CB  1 
ATOM   4481 C CG  . TYR B 1 367 ? 180.620 194.087 202.890 1.00 73.59  ? 367 TYR B CG  1 
ATOM   4482 C CD1 . TYR B 1 367 ? 181.579 194.584 203.762 1.00 72.50  ? 367 TYR B CD1 1 
ATOM   4483 C CD2 . TYR B 1 367 ? 181.019 193.743 201.605 1.00 72.71  ? 367 TYR B CD2 1 
ATOM   4484 C CE1 . TYR B 1 367 ? 182.896 194.723 203.370 1.00 76.11  ? 367 TYR B CE1 1 
ATOM   4485 C CE2 . TYR B 1 367 ? 182.333 193.878 201.205 1.00 76.33  ? 367 TYR B CE2 1 
ATOM   4486 C CZ  . TYR B 1 367 ? 183.267 194.369 202.091 1.00 78.18  ? 367 TYR B CZ  1 
ATOM   4487 O OH  . TYR B 1 367 ? 184.577 194.506 201.695 1.00 79.10  ? 367 TYR B OH  1 
ATOM   4488 N N   . TYR B 1 368 ? 176.896 191.273 204.588 1.00 82.97  ? 368 TYR B N   1 
ATOM   4489 C CA  . TYR B 1 368 ? 175.467 190.977 204.640 1.00 82.31  ? 368 TYR B CA  1 
ATOM   4490 C C   . TYR B 1 368 ? 174.729 191.920 205.583 1.00 86.23  ? 368 TYR B C   1 
ATOM   4491 O O   . TYR B 1 368 ? 173.629 192.384 205.266 1.00 87.93  ? 368 TYR B O   1 
ATOM   4492 C CB  . TYR B 1 368 ? 175.244 189.518 205.036 1.00 84.86  ? 368 TYR B CB  1 
ATOM   4493 C CG  . TYR B 1 368 ? 175.585 189.183 206.470 1.00 83.53  ? 368 TYR B CG  1 
ATOM   4494 C CD1 . TYR B 1 368 ? 176.906 189.040 206.875 1.00 83.16  ? 368 TYR B CD1 1 
ATOM   4495 C CD2 . TYR B 1 368 ? 174.586 188.992 207.415 1.00 83.85  ? 368 TYR B CD2 1 
ATOM   4496 C CE1 . TYR B 1 368 ? 177.222 188.727 208.182 1.00 86.18  ? 368 TYR B CE1 1 
ATOM   4497 C CE2 . TYR B 1 368 ? 174.892 188.678 208.724 1.00 83.32  ? 368 TYR B CE2 1 
ATOM   4498 C CZ  . TYR B 1 368 ? 176.212 188.548 209.103 1.00 85.72  ? 368 TYR B CZ  1 
ATOM   4499 O OH  . TYR B 1 368 ? 176.522 188.236 210.406 1.00 86.57  ? 368 TYR B OH  1 
ATOM   4500 N N   . LYS B 1 369 ? 175.317 192.225 206.742 1.00 88.72  ? 369 LYS B N   1 
ATOM   4501 C CA  . LYS B 1 369 ? 174.689 193.166 207.664 1.00 89.58  ? 369 LYS B CA  1 
ATOM   4502 C C   . LYS B 1 369 ? 174.533 194.538 207.018 1.00 87.07  ? 369 LYS B C   1 
ATOM   4503 O O   . LYS B 1 369 ? 173.441 195.121 207.006 1.00 86.84  ? 369 LYS B O   1 
ATOM   4504 C CB  . LYS B 1 369 ? 175.515 193.268 208.948 1.00 87.56  ? 369 LYS B CB  1 
ATOM   4505 C CG  . LYS B 1 369 ? 175.633 191.968 209.724 1.00 88.46  ? 369 LYS B CG  1 
ATOM   4506 C CD  . LYS B 1 369 ? 174.377 191.689 210.531 1.00 90.14  ? 369 LYS B CD  1 
ATOM   4507 C CE  . LYS B 1 369 ? 174.481 192.281 211.927 1.00 88.00  ? 369 LYS B CE  1 
ATOM   4508 N NZ  . LYS B 1 369 ? 175.461 191.543 212.771 1.00 88.83  ? 369 LYS B NZ  1 
ATOM   4509 N N   . SER B 1 370 ? 175.626 195.062 206.461 1.00 78.18  ? 370 SER B N   1 
ATOM   4510 C CA  . SER B 1 370 ? 175.599 196.380 205.837 1.00 77.64  ? 370 SER B CA  1 
ATOM   4511 C C   . SER B 1 370 ? 174.666 196.406 204.633 1.00 78.66  ? 370 SER B C   1 
ATOM   4512 O O   . SER B 1 370 ? 173.892 197.354 204.450 1.00 85.66  ? 370 SER B O   1 
ATOM   4513 C CB  . SER B 1 370 ? 177.018 196.781 205.434 1.00 80.34  ? 370 SER B CB  1 
ATOM   4514 O OG  . SER B 1 370 ? 177.005 197.705 204.363 1.00 79.75  ? 370 SER B OG  1 
ATOM   4515 N N   . ARG B 1 371 ? 174.726 195.367 203.798 1.00 81.29  ? 371 ARG B N   1 
ATOM   4516 C CA  . ARG B 1 371 ? 173.889 195.326 202.604 1.00 82.40  ? 371 ARG B CA  1 
ATOM   4517 C C   . ARG B 1 371 ? 172.413 195.251 202.968 1.00 83.59  ? 371 ARG B C   1 
ATOM   4518 O O   . ARG B 1 371 ? 171.573 195.907 202.343 1.00 85.16  ? 371 ARG B O   1 
ATOM   4519 C CB  . ARG B 1 371 ? 174.289 194.143 201.726 1.00 82.33  ? 371 ARG B CB  1 
ATOM   4520 C CG  . ARG B 1 371 ? 175.605 194.335 201.001 1.00 82.66  ? 371 ARG B CG  1 
ATOM   4521 C CD  . ARG B 1 371 ? 175.748 193.339 199.872 1.00 85.10  ? 371 ARG B CD  1 
ATOM   4522 N NE  . ARG B 1 371 ? 175.874 191.972 200.363 1.00 87.23  ? 371 ARG B NE  1 
ATOM   4523 C CZ  . ARG B 1 371 ? 174.936 191.043 200.238 1.00 86.83  ? 371 ARG B CZ  1 
ATOM   4524 N NH1 . ARG B 1 371 ? 173.784 191.299 199.640 1.00 86.33  ? 371 ARG B NH1 1 
ATOM   4525 N NH2 . ARG B 1 371 ? 175.160 189.826 200.727 1.00 85.88  ? 371 ARG B NH2 1 
ATOM   4526 N N   . PHE B 1 372 ? 172.074 194.449 203.980 1.00 82.60  ? 372 PHE B N   1 
ATOM   4527 C CA  . PHE B 1 372 ? 170.680 194.345 204.395 1.00 85.00  ? 372 PHE B CA  1 
ATOM   4528 C C   . PHE B 1 372 ? 170.192 195.645 205.019 1.00 87.93  ? 372 PHE B C   1 
ATOM   4529 O O   . PHE B 1 372 ? 169.043 196.049 204.805 1.00 88.33  ? 372 PHE B O   1 
ATOM   4530 C CB  . PHE B 1 372 ? 170.503 193.178 205.366 1.00 87.03  ? 372 PHE B CB  1 
ATOM   4531 C CG  . PHE B 1 372 ? 170.695 191.830 204.732 1.00 90.38  ? 372 PHE B CG  1 
ATOM   4532 C CD1 . PHE B 1 372 ? 170.547 191.667 203.365 1.00 88.58  ? 372 PHE B CD1 1 
ATOM   4533 C CD2 . PHE B 1 372 ? 171.018 190.726 205.503 1.00 87.89  ? 372 PHE B CD2 1 
ATOM   4534 C CE1 . PHE B 1 372 ? 170.723 190.430 202.778 1.00 89.06  ? 372 PHE B CE1 1 
ATOM   4535 C CE2 . PHE B 1 372 ? 171.195 189.486 204.921 1.00 87.41  ? 372 PHE B CE2 1 
ATOM   4536 C CZ  . PHE B 1 372 ? 171.047 189.338 203.557 1.00 90.89  ? 372 PHE B CZ  1 
ATOM   4537 N N   . TRP B 1 373 ? 171.048 196.317 205.795 1.00 80.90  ? 373 TRP B N   1 
ATOM   4538 C CA  . TRP B 1 373 ? 170.654 197.605 206.357 1.00 76.63  ? 373 TRP B CA  1 
ATOM   4539 C C   . TRP B 1 373 ? 170.420 198.626 205.251 1.00 75.25  ? 373 TRP B C   1 
ATOM   4540 O O   . TRP B 1 373 ? 169.446 199.389 205.295 1.00 74.93  ? 373 TRP B O   1 
ATOM   4541 C CB  . TRP B 1 373 ? 171.706 198.072 207.372 1.00 73.03  ? 373 TRP B CB  1 
ATOM   4542 C CG  . TRP B 1 373 ? 171.673 199.533 207.768 1.00 74.71  ? 373 TRP B CG  1 
ATOM   4543 C CD1 . TRP B 1 373 ? 171.266 200.033 208.971 1.00 81.19  ? 373 TRP B CD1 1 
ATOM   4544 C CD2 . TRP B 1 373 ? 172.189 200.654 207.030 1.00 77.06  ? 373 TRP B CD2 1 
ATOM   4545 N NE1 . TRP B 1 373 ? 171.418 201.396 208.998 1.00 83.22  ? 373 TRP B NE1 1 
ATOM   4546 C CE2 . TRP B 1 373 ? 171.991 201.802 207.823 1.00 80.90  ? 373 TRP B CE2 1 
ATOM   4547 C CE3 . TRP B 1 373 ? 172.771 200.803 205.768 1.00 78.42  ? 373 TRP B CE3 1 
ATOM   4548 C CZ2 . TRP B 1 373 ? 172.351 203.078 207.395 1.00 77.88  ? 373 TRP B CZ2 1 
ATOM   4549 C CZ3 . TRP B 1 373 ? 173.122 202.072 205.343 1.00 82.34  ? 373 TRP B CZ3 1 
ATOM   4550 C CH2 . TRP B 1 373 ? 172.913 203.192 206.155 1.00 78.17  ? 373 TRP B CH2 1 
ATOM   4551 N N   . LEU B 1 374 ? 171.277 198.625 204.226 1.00 72.12  ? 374 LEU B N   1 
ATOM   4552 C CA  . LEU B 1 374 ? 171.077 199.530 203.098 1.00 66.30  ? 374 LEU B CA  1 
ATOM   4553 C C   . LEU B 1 374 ? 169.798 199.200 202.341 1.00 70.60  ? 374 LEU B C   1 
ATOM   4554 O O   . LEU B 1 374 ? 169.067 200.106 201.932 1.00 78.24  ? 374 LEU B O   1 
ATOM   4555 C CB  . LEU B 1 374 ? 172.278 199.488 202.156 1.00 66.24  ? 374 LEU B CB  1 
ATOM   4556 C CG  . LEU B 1 374 ? 172.158 200.464 200.984 1.00 64.96  ? 374 LEU B CG  1 
ATOM   4557 C CD1 . LEU B 1 374 ? 172.336 201.891 201.470 1.00 66.63  ? 374 LEU B CD1 1 
ATOM   4558 C CD2 . LEU B 1 374 ? 173.155 200.143 199.884 1.00 69.99  ? 374 LEU B CD2 1 
ATOM   4559 N N   . LEU B 1 375 ? 169.515 197.912 202.135 1.00 70.50  ? 375 LEU B N   1 
ATOM   4560 C CA  . LEU B 1 375 ? 168.298 197.527 201.429 1.00 71.94  ? 375 LEU B CA  1 
ATOM   4561 C C   . LEU B 1 375 ? 167.053 197.950 202.198 1.00 80.18  ? 375 LEU B C   1 
ATOM   4562 O O   . LEU B 1 375 ? 166.117 198.516 201.619 1.00 79.89  ? 375 LEU B O   1 
ATOM   4563 C CB  . LEU B 1 375 ? 168.291 196.018 201.189 1.00 70.19  ? 375 LEU B CB  1 
ATOM   4564 C CG  . LEU B 1 375 ? 169.085 195.504 199.988 1.00 76.48  ? 375 LEU B CG  1 
ATOM   4565 C CD1 . LEU B 1 375 ? 168.497 194.196 199.492 1.00 80.20  ? 375 LEU B CD1 1 
ATOM   4566 C CD2 . LEU B 1 375 ? 169.100 196.537 198.874 1.00 77.16  ? 375 LEU B CD2 1 
ATOM   4567 N N   . LYS B 1 376 ? 167.030 197.693 203.509 1.00 80.60  ? 376 LYS B N   1 
ATOM   4568 C CA  . LYS B 1 376 ? 165.887 198.090 204.324 1.00 77.19  ? 376 LYS B CA  1 
ATOM   4569 C C   . LYS B 1 376 ? 165.704 199.601 204.314 1.00 75.32  ? 376 LYS B C   1 
ATOM   4570 O O   . LYS B 1 376 ? 164.581 200.099 204.158 1.00 73.31  ? 376 LYS B O   1 
ATOM   4571 C CB  . LYS B 1 376 ? 166.063 197.586 205.757 1.00 74.27  ? 376 LYS B CB  1 
ATOM   4572 C CG  . LYS B 1 376 ? 165.302 196.311 206.080 1.00 76.08  ? 376 LYS B CG  1 
ATOM   4573 C CD  . LYS B 1 376 ? 166.095 195.079 205.677 1.00 77.46  ? 376 LYS B CD  1 
ATOM   4574 C CE  . LYS B 1 376 ? 165.380 193.801 206.083 1.00 76.85  ? 376 LYS B CE  1 
ATOM   4575 N NZ  . LYS B 1 376 ? 166.128 192.587 205.654 1.00 74.09  ? 376 LYS B NZ  1 
ATOM   4576 N N   . LEU B 1 377 ? 166.799 200.349 204.463 1.00 69.97  ? 377 LEU B N   1 
ATOM   4577 C CA  . LEU B 1 377 ? 166.704 201.800 204.502 1.00 65.04  ? 377 LEU B CA  1 
ATOM   4578 C C   . LEU B 1 377 ? 166.302 202.381 203.151 1.00 66.50  ? 377 LEU B C   1 
ATOM   4579 O O   . LEU B 1 377 ? 165.548 203.356 203.105 1.00 71.25  ? 377 LEU B O   1 
ATOM   4580 C CB  . LEU B 1 377 ? 168.033 202.378 204.991 1.00 65.85  ? 377 LEU B CB  1 
ATOM   4581 C CG  . LEU B 1 377 ? 168.373 203.858 204.863 1.00 66.18  ? 377 LEU B CG  1 
ATOM   4582 C CD1 . LEU B 1 377 ? 169.320 204.205 205.975 1.00 70.60  ? 377 LEU B CD1 1 
ATOM   4583 C CD2 . LEU B 1 377 ? 169.034 204.149 203.547 1.00 65.42  ? 377 LEU B CD2 1 
ATOM   4584 N N   . LEU B 1 378 ? 166.781 201.801 202.047 1.00 64.12  ? 378 LEU B N   1 
ATOM   4585 C CA  . LEU B 1 378 ? 166.356 202.245 200.725 1.00 64.82  ? 378 LEU B CA  1 
ATOM   4586 C C   . LEU B 1 378 ? 164.881 201.955 200.483 1.00 72.99  ? 378 LEU B C   1 
ATOM   4587 O O   . LEU B 1 378 ? 164.175 202.787 199.900 1.00 76.50  ? 378 LEU B O   1 
ATOM   4588 C CB  . LEU B 1 378 ? 167.213 201.579 199.649 1.00 60.54  ? 378 LEU B CB  1 
ATOM   4589 C CG  . LEU B 1 378 ? 167.363 202.320 198.319 1.00 68.10  ? 378 LEU B CG  1 
ATOM   4590 C CD1 . LEU B 1 378 ? 168.774 202.162 197.775 1.00 69.44  ? 378 LEU B CD1 1 
ATOM   4591 C CD2 . LEU B 1 378 ? 166.340 201.825 197.309 1.00 72.14  ? 378 LEU B CD2 1 
ATOM   4592 N N   . PHE B 1 379 ? 164.401 200.785 200.913 1.00 78.64  ? 379 PHE B N   1 
ATOM   4593 C CA  . PHE B 1 379 ? 162.977 200.487 200.800 1.00 80.11  ? 379 PHE B CA  1 
ATOM   4594 C C   . PHE B 1 379 ? 162.152 201.478 201.612 1.00 79.50  ? 379 PHE B C   1 
ATOM   4595 O O   . PHE B 1 379 ? 161.094 201.935 201.165 1.00 77.70  ? 379 PHE B O   1 
ATOM   4596 C CB  . PHE B 1 379 ? 162.703 199.053 201.254 1.00 79.57  ? 379 PHE B CB  1 
ATOM   4597 C CG  . PHE B 1 379 ? 161.269 198.795 201.625 1.00 82.32  ? 379 PHE B CG  1 
ATOM   4598 C CD1 . PHE B 1 379 ? 160.261 198.920 200.682 1.00 81.01  ? 379 PHE B CD1 1 
ATOM   4599 C CD2 . PHE B 1 379 ? 160.930 198.430 202.917 1.00 80.90  ? 379 PHE B CD2 1 
ATOM   4600 C CE1 . PHE B 1 379 ? 158.943 198.684 201.022 1.00 79.87  ? 379 PHE B CE1 1 
ATOM   4601 C CE2 . PHE B 1 379 ? 159.613 198.193 203.262 1.00 79.84  ? 379 PHE B CE2 1 
ATOM   4602 C CZ  . PHE B 1 379 ? 158.618 198.320 202.313 1.00 79.18  ? 379 PHE B CZ  1 
ATOM   4603 N N   . ARG B 1 380 ? 162.623 201.817 202.814 1.00 75.14  ? 380 ARG B N   1 
ATOM   4604 C CA  . ARG B 1 380 ? 161.936 202.818 203.624 1.00 71.91  ? 380 ARG B CA  1 
ATOM   4605 C C   . ARG B 1 380 ? 161.938 204.181 202.940 1.00 69.96  ? 380 ARG B C   1 
ATOM   4606 O O   . ARG B 1 380 ? 160.931 204.898 202.964 1.00 70.79  ? 380 ARG B O   1 
ATOM   4607 C CB  . ARG B 1 380 ? 162.588 202.905 205.004 1.00 68.82  ? 380 ARG B CB  1 
ATOM   4608 C CG  . ARG B 1 380 ? 162.081 204.043 205.871 1.00 69.66  ? 380 ARG B CG  1 
ATOM   4609 C CD  . ARG B 1 380 ? 162.088 203.663 207.344 1.00 71.95  ? 380 ARG B CD  1 
ATOM   4610 N NE  . ARG B 1 380 ? 163.439 203.474 207.859 1.00 73.42  ? 380 ARG B NE  1 
ATOM   4611 C CZ  . ARG B 1 380 ? 164.007 202.293 208.059 1.00 72.65  ? 380 ARG B CZ  1 
ATOM   4612 N NH1 . ARG B 1 380 ? 163.366 201.165 207.798 1.00 73.04  ? 380 ARG B NH1 1 
ATOM   4613 N NH2 . ARG B 1 380 ? 165.248 202.242 208.534 1.00 74.04  ? 380 ARG B NH2 1 
ATOM   4614 N N   . VAL B 1 381 ? 163.064 204.556 202.330 1.00 67.12  ? 381 VAL B N   1 
ATOM   4615 C CA  . VAL B 1 381 ? 163.176 205.863 201.688 1.00 67.42  ? 381 VAL B CA  1 
ATOM   4616 C C   . VAL B 1 381 ? 162.228 205.959 200.499 1.00 64.72  ? 381 VAL B C   1 
ATOM   4617 O O   . VAL B 1 381 ? 161.518 206.958 200.331 1.00 71.69  ? 381 VAL B O   1 
ATOM   4618 C CB  . VAL B 1 381 ? 164.634 206.128 201.269 1.00 64.06  ? 381 VAL B CB  1 
ATOM   4619 C CG1 . VAL B 1 381 ? 164.693 207.126 200.121 1.00 60.30  ? 381 VAL B CG1 1 
ATOM   4620 C CG2 . VAL B 1 381 ? 165.440 206.625 202.452 1.00 68.75  ? 381 VAL B CG2 1 
ATOM   4621 N N   . PHE B 1 382 ? 162.200 204.923 199.657 1.00 67.09  ? 382 PHE B N   1 
ATOM   4622 C CA  . PHE B 1 382 ? 161.348 204.969 198.473 1.00 72.24  ? 382 PHE B CA  1 
ATOM   4623 C C   . PHE B 1 382 ? 159.872 205.012 198.847 1.00 77.31  ? 382 PHE B C   1 
ATOM   4624 O O   . PHE B 1 382 ? 159.059 205.570 198.103 1.00 76.92  ? 382 PHE B O   1 
ATOM   4625 C CB  . PHE B 1 382 ? 161.644 203.777 197.563 1.00 77.35  ? 382 PHE B CB  1 
ATOM   4626 C CG  . PHE B 1 382 ? 162.576 204.101 196.430 1.00 76.93  ? 382 PHE B CG  1 
ATOM   4627 C CD1 . PHE B 1 382 ? 163.426 205.192 196.509 1.00 73.75  ? 382 PHE B CD1 1 
ATOM   4628 C CD2 . PHE B 1 382 ? 162.601 203.320 195.288 1.00 76.30  ? 382 PHE B CD2 1 
ATOM   4629 C CE1 . PHE B 1 382 ? 164.286 205.497 195.471 1.00 71.56  ? 382 PHE B CE1 1 
ATOM   4630 C CE2 . PHE B 1 382 ? 163.459 203.621 194.245 1.00 75.50  ? 382 PHE B CE2 1 
ATOM   4631 C CZ  . PHE B 1 382 ? 164.302 204.711 194.338 1.00 74.74  ? 382 PHE B CZ  1 
ATOM   4632 N N   . THR B 1 383 ? 159.509 204.430 199.989 1.00 82.67  ? 383 THR B N   1 
ATOM   4633 C CA  . THR B 1 383 ? 158.163 204.577 200.546 1.00 81.87  ? 383 THR B CA  1 
ATOM   4634 C C   . THR B 1 383 ? 158.170 205.736 201.545 1.00 79.35  ? 383 THR B C   1 
ATOM   4635 O O   . THR B 1 383 ? 158.093 205.565 202.762 1.00 81.04  ? 383 THR B O   1 
ATOM   4636 C CB  . THR B 1 383 ? 157.706 203.274 201.188 1.00 81.96  ? 383 THR B CB  1 
ATOM   4637 O OG1 . THR B 1 383 ? 158.661 202.865 202.174 1.00 82.04  ? 383 THR B OG1 1 
ATOM   4638 C CG2 . THR B 1 383 ? 157.574 202.183 200.137 1.00 79.92  ? 383 THR B CG2 1 
ATOM   4639 N N   . ALA B 1 384 ? 158.269 206.943 200.987 1.00 80.68  ? 384 ALA B N   1 
ATOM   4640 C CA  . ALA B 1 384 ? 158.515 208.131 201.803 1.00 84.95  ? 384 ALA B CA  1 
ATOM   4641 C C   . ALA B 1 384 ? 157.420 208.427 202.825 1.00 90.60  ? 384 ALA B C   1 
ATOM   4642 O O   . ALA B 1 384 ? 157.750 208.589 204.012 1.00 88.47  ? 384 ALA B O   1 
ATOM   4643 C CB  . ALA B 1 384 ? 158.753 209.335 200.885 1.00 82.51  ? 384 ALA B CB  1 
ATOM   4644 N N   . PRO B 1 385 ? 156.135 208.513 202.468 1.00 96.60  ? 385 PRO B N   1 
ATOM   4645 C CA  . PRO B 1 385 ? 155.137 209.004 203.424 1.00 90.87  ? 385 PRO B CA  1 
ATOM   4646 C C   . PRO B 1 385 ? 154.593 207.958 204.386 1.00 91.35  ? 385 PRO B C   1 
ATOM   4647 O O   . PRO B 1 385 ? 153.646 208.261 205.116 1.00 91.85  ? 385 PRO B O   1 
ATOM   4648 C CB  . PRO B 1 385 ? 154.022 209.517 202.502 1.00 87.24  ? 385 PRO B CB  1 
ATOM   4649 C CG  . PRO B 1 385 ? 154.072 208.601 201.342 1.00 88.97  ? 385 PRO B CG  1 
ATOM   4650 C CD  . PRO B 1 385 ? 155.510 208.170 201.175 1.00 91.76  ? 385 PRO B CD  1 
ATOM   4651 N N   . PHE B 1 386 ? 155.148 206.748 204.421 1.00 91.04  ? 386 PHE B N   1 
ATOM   4652 C CA  . PHE B 1 386 ? 154.604 205.681 205.250 1.00 91.68  ? 386 PHE B CA  1 
ATOM   4653 C C   . PHE B 1 386 ? 155.475 205.333 206.450 1.00 92.26  ? 386 PHE B C   1 
ATOM   4654 O O   . PHE B 1 386 ? 155.097 204.457 207.235 1.00 93.13  ? 386 PHE B O   1 
ATOM   4655 C CB  . PHE B 1 386 ? 154.365 204.426 204.401 1.00 90.98  ? 386 PHE B CB  1 
ATOM   4656 C CG  . PHE B 1 386 ? 153.757 204.712 203.056 1.00 91.99  ? 386 PHE B CG  1 
ATOM   4657 C CD1 . PHE B 1 386 ? 152.588 205.448 202.952 1.00 91.50  ? 386 PHE B CD1 1 
ATOM   4658 C CD2 . PHE B 1 386 ? 154.352 204.244 201.897 1.00 90.27  ? 386 PHE B CD2 1 
ATOM   4659 C CE1 . PHE B 1 386 ? 152.026 205.712 201.718 1.00 92.10  ? 386 PHE B CE1 1 
ATOM   4660 C CE2 . PHE B 1 386 ? 153.795 204.505 200.660 1.00 87.90  ? 386 PHE B CE2 1 
ATOM   4661 C CZ  . PHE B 1 386 ? 152.630 205.240 200.570 1.00 89.71  ? 386 PHE B CZ  1 
ATOM   4662 N N   . HIS B 1 387 ? 156.624 205.986 206.620 1.00 89.94  ? 387 HIS B N   1 
ATOM   4663 C CA  . HIS B 1 387 ? 157.479 205.746 207.774 1.00 90.04  ? 387 HIS B CA  1 
ATOM   4664 C C   . HIS B 1 387 ? 158.047 207.065 208.276 1.00 91.65  ? 387 HIS B C   1 
ATOM   4665 O O   . HIS B 1 387 ? 158.156 208.038 207.526 1.00 91.50  ? 387 HIS B O   1 
ATOM   4666 C CB  . HIS B 1 387 ? 158.626 204.778 207.450 1.00 88.23  ? 387 HIS B CB  1 
ATOM   4667 C CG  . HIS B 1 387 ? 158.270 203.734 206.439 1.00 91.47  ? 387 HIS B CG  1 
ATOM   4668 N ND1 . HIS B 1 387 ? 157.638 202.557 206.775 1.00 92.73  ? 387 HIS B ND1 1 
ATOM   4669 C CD2 . HIS B 1 387 ? 158.459 203.690 205.099 1.00 93.09  ? 387 HIS B CD2 1 
ATOM   4670 C CE1 . HIS B 1 387 ? 157.452 201.832 205.687 1.00 94.64  ? 387 HIS B CE1 1 
ATOM   4671 N NE2 . HIS B 1 387 ? 157.941 202.497 204.655 1.00 94.11  ? 387 HIS B NE2 1 
ATOM   4672 N N   . LYS B 1 388 ? 158.405 207.084 209.557 1.00 89.85  ? 388 LYS B N   1 
ATOM   4673 C CA  . LYS B 1 388 ? 159.009 208.267 210.152 1.00 87.49  ? 388 LYS B CA  1 
ATOM   4674 C C   . LYS B 1 388 ? 160.380 208.525 209.539 1.00 89.85  ? 388 LYS B C   1 
ATOM   4675 O O   . LYS B 1 388 ? 161.158 207.596 209.305 1.00 89.71  ? 388 LYS B O   1 
ATOM   4676 C CB  . LYS B 1 388 ? 159.127 208.099 211.667 1.00 88.75  ? 388 LYS B CB  1 
ATOM   4677 C CG  . LYS B 1 388 ? 159.758 209.284 212.381 1.00 90.44  ? 388 LYS B CG  1 
ATOM   4678 C CD  . LYS B 1 388 ? 159.873 209.035 213.877 1.00 90.45  ? 388 LYS B CD  1 
ATOM   4679 C CE  . LYS B 1 388 ? 158.549 208.578 214.467 1.00 92.60  ? 388 LYS B CE  1 
ATOM   4680 N NZ  . LYS B 1 388 ? 157.453 209.548 214.193 1.00 93.15  ? 388 LYS B NZ  1 
ATOM   4681 N N   . VAL B 1 389 ? 160.674 209.796 209.281 1.00 74.22  ? 389 VAL B N   1 
ATOM   4682 C CA  . VAL B 1 389 ? 161.900 210.191 208.598 1.00 76.21  ? 389 VAL B CA  1 
ATOM   4683 C C   . VAL B 1 389 ? 162.994 210.343 209.650 1.00 74.93  ? 389 VAL B C   1 
ATOM   4684 O O   . VAL B 1 389 ? 163.094 211.373 210.319 1.00 72.04  ? 389 VAL B O   1 
ATOM   4685 C CB  . VAL B 1 389 ? 161.710 211.476 207.791 1.00 73.17  ? 389 VAL B CB  1 
ATOM   4686 C CG1 . VAL B 1 389 ? 162.956 211.775 206.973 1.00 73.49  ? 389 VAL B CG1 1 
ATOM   4687 C CG2 . VAL B 1 389 ? 160.492 211.358 206.890 1.00 74.52  ? 389 VAL B CG2 1 
ATOM   4688 N N   . GLY B 1 390 ? 163.819 209.308 209.798 1.00 66.50  ? 390 GLY B N   1 
ATOM   4689 C CA  . GLY B 1 390 ? 165.013 209.400 210.607 1.00 64.00  ? 390 GLY B CA  1 
ATOM   4690 C C   . GLY B 1 390 ? 166.116 210.136 209.875 1.00 63.34  ? 390 GLY B C   1 
ATOM   4691 O O   . GLY B 1 390 ? 165.973 210.555 208.726 1.00 69.27  ? 390 GLY B O   1 
ATOM   4692 N N   . PHE B 1 391 ? 167.246 210.305 210.565 1.00 52.67  ? 391 PHE B N   1 
ATOM   4693 C CA  . PHE B 1 391 ? 168.366 211.010 209.950 1.00 53.83  ? 391 PHE B CA  1 
ATOM   4694 C C   . PHE B 1 391 ? 168.903 210.257 208.743 1.00 48.94  ? 391 PHE B C   1 
ATOM   4695 O O   . PHE B 1 391 ? 169.249 210.869 207.729 1.00 58.41  ? 391 PHE B O   1 
ATOM   4696 C CB  . PHE B 1 391 ? 169.492 211.237 210.955 1.00 55.64  ? 391 PHE B CB  1 
ATOM   4697 C CG  . PHE B 1 391 ? 170.706 211.881 210.346 1.00 49.46  ? 391 PHE B CG  1 
ATOM   4698 C CD1 . PHE B 1 391 ? 170.738 213.243 210.112 1.00 50.12  ? 391 PHE B CD1 1 
ATOM   4699 C CD2 . PHE B 1 391 ? 171.799 211.118 209.972 1.00 49.10  ? 391 PHE B CD2 1 
ATOM   4700 C CE1 . PHE B 1 391 ? 171.844 213.834 209.537 1.00 46.06  ? 391 PHE B CE1 1 
ATOM   4701 C CE2 . PHE B 1 391 ? 172.908 211.706 209.397 1.00 47.98  ? 391 PHE B CE2 1 
ATOM   4702 C CZ  . PHE B 1 391 ? 172.931 213.066 209.182 1.00 46.66  ? 391 PHE B CZ  1 
ATOM   4703 N N   . ALA B 1 392 ? 169.006 208.933 208.843 1.00 37.71  ? 392 ALA B N   1 
ATOM   4704 C CA  . ALA B 1 392 ? 169.614 208.156 207.769 1.00 42.39  ? 392 ALA B CA  1 
ATOM   4705 C C   . ALA B 1 392 ? 168.753 208.167 206.510 1.00 49.10  ? 392 ALA B C   1 
ATOM   4706 O O   . ALA B 1 392 ? 169.280 208.217 205.389 1.00 43.84  ? 392 ALA B O   1 
ATOM   4707 C CB  . ALA B 1 392 ? 169.869 206.729 208.249 1.00 41.79  ? 392 ALA B CB  1 
ATOM   4708 N N   . ASP B 1 393 ? 167.428 208.116 206.671 1.00 61.59  ? 393 ASP B N   1 
ATOM   4709 C CA  . ASP B 1 393 ? 166.538 208.152 205.515 1.00 58.57  ? 393 ASP B CA  1 
ATOM   4710 C C   . ASP B 1 393 ? 166.654 209.480 204.776 1.00 49.01  ? 393 ASP B C   1 
ATOM   4711 O O   . ASP B 1 393 ? 166.818 209.508 203.550 1.00 59.29  ? 393 ASP B O   1 
ATOM   4712 C CB  . ASP B 1 393 ? 165.096 207.906 205.957 1.00 58.48  ? 393 ASP B CB  1 
ATOM   4713 C CG  . ASP B 1 393 ? 164.969 206.724 206.896 1.00 64.86  ? 393 ASP B CG  1 
ATOM   4714 O OD1 . ASP B 1 393 ? 164.921 205.576 206.407 1.00 67.26  ? 393 ASP B OD1 1 
ATOM   4715 O OD2 . ASP B 1 393 ? 164.918 206.942 208.125 1.00 59.95  ? 393 ASP B OD2 1 
ATOM   4716 N N   . PHE B 1 394 ? 166.570 210.591 205.513 1.00 26.53  ? 394 PHE B N   1 
ATOM   4717 C CA  . PHE B 1 394 ? 166.807 211.905 204.925 1.00 32.47  ? 394 PHE B CA  1 
ATOM   4718 C C   . PHE B 1 394 ? 168.181 211.984 204.279 1.00 38.59  ? 394 PHE B C   1 
ATOM   4719 O O   . PHE B 1 394 ? 168.331 212.575 203.203 1.00 47.77  ? 394 PHE B O   1 
ATOM   4720 C CB  . PHE B 1 394 ? 166.664 212.985 206.000 1.00 40.03  ? 394 PHE B CB  1 
ATOM   4721 C CG  . PHE B 1 394 ? 167.689 214.084 205.906 1.00 43.46  ? 394 PHE B CG  1 
ATOM   4722 C CD1 . PHE B 1 394 ? 167.610 215.053 204.919 1.00 54.33  ? 394 PHE B CD1 1 
ATOM   4723 C CD2 . PHE B 1 394 ? 168.743 214.137 206.802 1.00 36.98  ? 394 PHE B CD2 1 
ATOM   4724 C CE1 . PHE B 1 394 ? 168.557 216.056 204.834 1.00 47.69  ? 394 PHE B CE1 1 
ATOM   4725 C CE2 . PHE B 1 394 ? 169.692 215.136 206.720 1.00 35.87  ? 394 PHE B CE2 1 
ATOM   4726 C CZ  . PHE B 1 394 ? 169.599 216.096 205.735 1.00 36.27  ? 394 PHE B CZ  1 
ATOM   4727 N N   . TRP B 1 395 ? 169.190 211.399 204.922 1.00 42.60  ? 395 TRP B N   1 
ATOM   4728 C CA  . TRP B 1 395 ? 170.550 211.475 204.408 1.00 42.02  ? 395 TRP B CA  1 
ATOM   4729 C C   . TRP B 1 395 ? 170.657 210.801 203.047 1.00 47.79  ? 395 TRP B C   1 
ATOM   4730 O O   . TRP B 1 395 ? 171.144 211.405 202.086 1.00 52.64  ? 395 TRP B O   1 
ATOM   4731 C CB  . TRP B 1 395 ? 171.511 210.845 205.416 1.00 43.15  ? 395 TRP B CB  1 
ATOM   4732 C CG  . TRP B 1 395 ? 172.928 210.804 204.964 1.00 43.42  ? 395 TRP B CG  1 
ATOM   4733 C CD1 . TRP B 1 395 ? 173.873 211.767 205.149 1.00 41.76  ? 395 TRP B CD1 1 
ATOM   4734 C CD2 . TRP B 1 395 ? 173.572 209.736 204.264 1.00 50.65  ? 395 TRP B CD2 1 
ATOM   4735 N NE1 . TRP B 1 395 ? 175.066 211.370 204.600 1.00 54.93  ? 395 TRP B NE1 1 
ATOM   4736 C CE2 . TRP B 1 395 ? 174.908 210.125 204.050 1.00 48.69  ? 395 TRP B CE2 1 
ATOM   4737 C CE3 . TRP B 1 395 ? 173.149 208.491 203.793 1.00 49.73  ? 395 TRP B CE3 1 
ATOM   4738 C CZ2 . TRP B 1 395 ? 175.822 209.315 203.387 1.00 37.92  ? 395 TRP B CZ2 1 
ATOM   4739 C CZ3 . TRP B 1 395 ? 174.056 207.689 203.135 1.00 46.01  ? 395 TRP B CZ3 1 
ATOM   4740 C CH2 . TRP B 1 395 ? 175.378 208.103 202.938 1.00 44.94  ? 395 TRP B CH2 1 
ATOM   4741 N N   . LEU B 1 396 ? 170.171 209.560 202.934 1.00 51.33  ? 396 LEU B N   1 
ATOM   4742 C CA  . LEU B 1 396 ? 170.249 208.883 201.642 1.00 48.69  ? 396 LEU B CA  1 
ATOM   4743 C C   . LEU B 1 396 ? 169.332 209.530 200.611 1.00 52.06  ? 396 LEU B C   1 
ATOM   4744 O O   . LEU B 1 396 ? 169.653 209.532 199.418 1.00 54.92  ? 396 LEU B O   1 
ATOM   4745 C CB  . LEU B 1 396 ? 169.921 207.394 201.764 1.00 39.11  ? 396 LEU B CB  1 
ATOM   4746 C CG  . LEU B 1 396 ? 170.256 206.682 200.442 1.00 42.40  ? 396 LEU B CG  1 
ATOM   4747 C CD1 . LEU B 1 396 ? 171.738 206.841 200.112 1.00 46.83  ? 396 LEU B CD1 1 
ATOM   4748 C CD2 . LEU B 1 396 ? 169.848 205.221 200.399 1.00 49.88  ? 396 LEU B CD2 1 
ATOM   4749 N N   . ALA B 1 397 ? 168.193 210.082 201.038 1.00 41.11  ? 397 ALA B N   1 
ATOM   4750 C CA  . ALA B 1 397 ? 167.336 210.788 200.093 1.00 30.29  ? 397 ALA B CA  1 
ATOM   4751 C C   . ALA B 1 397 ? 168.052 211.999 199.509 1.00 37.58  ? 397 ALA B C   1 
ATOM   4752 O O   . ALA B 1 397 ? 167.954 212.271 198.308 1.00 53.00  ? 397 ALA B O   1 
ATOM   4753 C CB  . ALA B 1 397 ? 166.032 211.198 200.772 1.00 42.73  ? 397 ALA B CB  1 
ATOM   4754 N N   . ASP B 1 398 ? 168.800 212.727 200.339 1.00 32.43  ? 398 ASP B N   1 
ATOM   4755 C CA  . ASP B 1 398 ? 169.579 213.851 199.828 1.00 40.23  ? 398 ASP B CA  1 
ATOM   4756 C C   . ASP B 1 398 ? 170.725 213.373 198.940 1.00 47.72  ? 398 ASP B C   1 
ATOM   4757 O O   . ASP B 1 398 ? 171.054 214.018 197.934 1.00 53.92  ? 398 ASP B O   1 
ATOM   4758 C CB  . ASP B 1 398 ? 170.103 214.691 200.990 1.00 44.38  ? 398 ASP B CB  1 
ATOM   4759 C CG  . ASP B 1 398 ? 170.217 216.158 200.639 1.00 50.51  ? 398 ASP B CG  1 
ATOM   4760 O OD1 . ASP B 1 398 ? 169.893 216.520 199.489 1.00 51.41  ? 398 ASP B OD1 1 
ATOM   4761 O OD2 . ASP B 1 398 ? 170.629 216.950 201.511 1.00 52.04  ? 398 ASP B OD2 1 
ATOM   4762 N N   . GLN B 1 399 ? 171.349 212.246 199.296 1.00 44.79  ? 399 GLN B N   1 
ATOM   4763 C CA  . GLN B 1 399 ? 172.386 211.681 198.436 1.00 39.73  ? 399 GLN B CA  1 
ATOM   4764 C C   . GLN B 1 399 ? 171.826 211.375 197.053 1.00 42.84  ? 399 GLN B C   1 
ATOM   4765 O O   . GLN B 1 399 ? 172.451 211.684 196.032 1.00 44.10  ? 399 GLN B O   1 
ATOM   4766 C CB  . GLN B 1 399 ? 172.977 210.415 199.062 1.00 42.15  ? 399 GLN B CB  1 
ATOM   4767 C CG  . GLN B 1 399 ? 173.494 210.572 200.480 1.00 39.77  ? 399 GLN B CG  1 
ATOM   4768 C CD  . GLN B 1 399 ? 174.707 211.467 200.581 1.00 45.87  ? 399 GLN B CD  1 
ATOM   4769 O OE1 . GLN B 1 399 ? 174.974 212.051 201.629 1.00 49.31  ? 399 GLN B OE1 1 
ATOM   4770 N NE2 . GLN B 1 399 ? 175.453 211.576 199.495 1.00 53.02  ? 399 GLN B NE2 1 
ATOM   4771 N N   . LEU B 1 400 ? 170.637 210.770 197.007 1.00 44.51  ? 400 LEU B N   1 
ATOM   4772 C CA  . LEU B 1 400 ? 169.960 210.542 195.735 1.00 45.76  ? 400 LEU B CA  1 
ATOM   4773 C C   . LEU B 1 400 ? 169.636 211.855 195.038 1.00 47.21  ? 400 LEU B C   1 
ATOM   4774 O O   . LEU B 1 400 ? 169.715 211.941 193.807 1.00 52.23  ? 400 LEU B O   1 
ATOM   4775 C CB  . LEU B 1 400 ? 168.684 209.730 195.956 1.00 42.69  ? 400 LEU B CB  1 
ATOM   4776 C CG  . LEU B 1 400 ? 168.767 208.230 195.676 1.00 47.52  ? 400 LEU B CG  1 
ATOM   4777 C CD1 . LEU B 1 400 ? 169.639 207.538 196.711 1.00 47.13  ? 400 LEU B CD1 1 
ATOM   4778 C CD2 . LEU B 1 400 ? 167.377 207.615 195.643 1.00 41.82  ? 400 LEU B CD2 1 
ATOM   4779 N N   . ASN B 1 401 ? 169.261 212.882 195.806 1.00 55.85  ? 401 ASN B N   1 
ATOM   4780 C CA  . ASN B 1 401 ? 169.068 214.211 195.236 1.00 57.47  ? 401 ASN B CA  1 
ATOM   4781 C C   . ASN B 1 401 ? 170.320 214.695 194.522 1.00 51.67  ? 401 ASN B C   1 
ATOM   4782 O O   . ASN B 1 401 ? 170.226 215.414 193.521 1.00 57.20  ? 401 ASN B O   1 
ATOM   4783 C CB  . ASN B 1 401 ? 168.664 215.202 196.328 1.00 56.58  ? 401 ASN B CB  1 
ATOM   4784 C CG  . ASN B 1 401 ? 167.636 216.206 195.854 1.00 59.78  ? 401 ASN B CG  1 
ATOM   4785 O OD1 . ASN B 1 401 ? 166.594 215.836 195.316 1.00 62.03  ? 401 ASN B OD1 1 
ATOM   4786 N ND2 . ASN B 1 401 ? 167.926 217.486 196.051 1.00 61.33  ? 401 ASN B ND2 1 
ATOM   4787 N N   . SER B 1 402 ? 171.496 214.315 195.016 1.00 42.82  ? 402 SER B N   1 
ATOM   4788 C CA  . SER B 1 402 ? 172.745 214.601 194.322 1.00 47.12  ? 402 SER B CA  1 
ATOM   4789 C C   . SER B 1 402 ? 173.208 213.462 193.425 1.00 59.42  ? 402 SER B C   1 
ATOM   4790 O O   . SER B 1 402 ? 174.306 213.542 192.865 1.00 54.22  ? 402 SER B O   1 
ATOM   4791 C CB  . SER B 1 402 ? 173.848 214.939 195.323 1.00 44.64  ? 402 SER B CB  1 
ATOM   4792 O OG  . SER B 1 402 ? 173.659 216.232 195.866 1.00 51.59  ? 402 SER B OG  1 
ATOM   4793 N N   . LEU B 1 403 ? 172.415 212.402 193.283 1.00 59.74  ? 403 LEU B N   1 
ATOM   4794 C CA  . LEU B 1 403 ? 172.741 211.295 192.392 1.00 43.90  ? 403 LEU B CA  1 
ATOM   4795 C C   . LEU B 1 403 ? 171.648 211.077 191.351 1.00 41.84  ? 403 LEU B C   1 
ATOM   4796 O O   . LEU B 1 403 ? 171.440 209.955 190.888 1.00 53.41  ? 403 LEU B O   1 
ATOM   4797 C CB  . LEU B 1 403 ? 172.989 210.012 193.183 1.00 42.30  ? 403 LEU B CB  1 
ATOM   4798 C CG  . LEU B 1 403 ? 174.274 209.957 194.009 1.00 39.30  ? 403 LEU B CG  1 
ATOM   4799 C CD1 . LEU B 1 403 ? 174.432 208.591 194.652 1.00 40.13  ? 403 LEU B CD1 1 
ATOM   4800 C CD2 . LEU B 1 403 ? 175.479 210.290 193.145 1.00 41.16  ? 403 LEU B CD2 1 
ATOM   4801 N N   . SER B 1 404 ? 170.946 212.149 190.974 1.00 40.37  ? 404 SER B N   1 
ATOM   4802 C CA  . SER B 1 404 ? 169.893 212.031 189.970 1.00 44.32  ? 404 SER B CA  1 
ATOM   4803 C C   . SER B 1 404 ? 170.442 211.552 188.635 1.00 50.63  ? 404 SER B C   1 
ATOM   4804 O O   . SER B 1 404 ? 169.717 210.923 187.854 1.00 50.43  ? 404 SER B O   1 
ATOM   4805 C CB  . SER B 1 404 ? 169.180 213.372 189.796 1.00 51.34  ? 404 SER B CB  1 
ATOM   4806 O OG  . SER B 1 404 ? 170.079 214.372 189.351 1.00 52.40  ? 404 SER B OG  1 
ATOM   4807 N N   . VAL B 1 405 ? 171.717 211.837 188.357 1.00 60.69  ? 405 VAL B N   1 
ATOM   4808 C CA  . VAL B 1 405 ? 172.322 211.402 187.104 1.00 55.58  ? 405 VAL B CA  1 
ATOM   4809 C C   . VAL B 1 405 ? 172.345 209.883 187.016 1.00 49.95  ? 405 VAL B C   1 
ATOM   4810 O O   . VAL B 1 405 ? 172.204 209.320 185.927 1.00 54.08  ? 405 VAL B O   1 
ATOM   4811 C CB  . VAL B 1 405 ? 173.734 212.000 186.952 1.00 49.00  ? 405 VAL B CB  1 
ATOM   4812 C CG1 . VAL B 1 405 ? 174.319 211.639 185.596 1.00 51.75  ? 405 VAL B CG1 1 
ATOM   4813 C CG2 . VAL B 1 405 ? 173.690 213.508 187.130 1.00 57.65  ? 405 VAL B CG2 1 
ATOM   4814 N N   . ILE B 1 406 ? 172.509 209.195 188.147 1.00 44.66  ? 406 ILE B N   1 
ATOM   4815 C CA  . ILE B 1 406 ? 172.552 207.734 188.125 1.00 40.94  ? 406 ILE B CA  1 
ATOM   4816 C C   . ILE B 1 406 ? 171.214 207.163 187.663 1.00 49.58  ? 406 ILE B C   1 
ATOM   4817 O O   . ILE B 1 406 ? 171.159 206.331 186.749 1.00 54.28  ? 406 ILE B O   1 
ATOM   4818 C CB  . ILE B 1 406 ? 172.959 207.190 189.506 1.00 43.73  ? 406 ILE B CB  1 
ATOM   4819 C CG1 . ILE B 1 406 ? 174.481 207.222 189.657 1.00 43.26  ? 406 ILE B CG1 1 
ATOM   4820 C CG2 . ILE B 1 406 ? 172.441 205.774 189.702 1.00 44.17  ? 406 ILE B CG2 1 
ATOM   4821 C CD1 . ILE B 1 406 ? 174.957 207.051 191.080 1.00 50.66  ? 406 ILE B CD1 1 
ATOM   4822 N N   . LEU B 1 407 ? 170.112 207.616 188.270 1.00 62.09  ? 407 LEU B N   1 
ATOM   4823 C CA  . LEU B 1 407 ? 168.796 207.139 187.852 1.00 61.91  ? 407 LEU B CA  1 
ATOM   4824 C C   . LEU B 1 407 ? 168.463 207.576 186.431 1.00 58.99  ? 407 LEU B C   1 
ATOM   4825 O O   . LEU B 1 407 ? 167.851 206.814 185.675 1.00 63.23  ? 407 LEU B O   1 
ATOM   4826 C CB  . LEU B 1 407 ? 167.708 207.625 188.814 1.00 56.71  ? 407 LEU B CB  1 
ATOM   4827 C CG  . LEU B 1 407 ? 167.896 207.482 190.327 1.00 59.58  ? 407 LEU B CG  1 
ATOM   4828 C CD1 . LEU B 1 407 ? 168.516 208.727 190.933 1.00 54.66  ? 407 LEU B CD1 1 
ATOM   4829 C CD2 . LEU B 1 407 ? 166.566 207.168 191.000 1.00 62.02  ? 407 LEU B CD2 1 
ATOM   4830 N N   . MET B 1 408 ? 168.843 208.798 186.057 1.00 63.18  ? 408 MET B N   1 
ATOM   4831 C CA  . MET B 1 408 ? 168.578 209.283 184.707 1.00 67.71  ? 408 MET B CA  1 
ATOM   4832 C C   . MET B 1 408 ? 169.321 208.459 183.659 1.00 72.88  ? 408 MET B C   1 
ATOM   4833 O O   . MET B 1 408 ? 168.757 208.117 182.612 1.00 71.83  ? 408 MET B O   1 
ATOM   4834 C CB  . MET B 1 408 ? 168.957 210.758 184.625 1.00 65.58  ? 408 MET B CB  1 
ATOM   4835 C CG  . MET B 1 408 ? 167.811 211.696 184.953 1.00 67.63  ? 408 MET B CG  1 
ATOM   4836 S SD  . MET B 1 408 ? 168.327 213.420 184.992 1.00 75.47  ? 408 MET B SD  1 
ATOM   4837 C CE  . MET B 1 408 ? 169.890 213.325 184.139 1.00 71.85  ? 408 MET B CE  1 
ATOM   4838 N N   . ASP B 1 409 ? 170.583 208.117 183.929 1.00 71.04  ? 409 ASP B N   1 
ATOM   4839 C CA  . ASP B 1 409 ? 171.340 207.266 183.022 1.00 61.10  ? 409 ASP B CA  1 
ATOM   4840 C C   . ASP B 1 409 ? 170.788 205.849 183.000 1.00 58.57  ? 409 ASP B C   1 
ATOM   4841 O O   . ASP B 1 409 ? 170.819 205.193 181.956 1.00 63.56  ? 409 ASP B O   1 
ATOM   4842 C CB  . ASP B 1 409 ? 172.816 207.258 183.419 1.00 55.49  ? 409 ASP B CB  1 
ATOM   4843 C CG  . ASP B 1 409 ? 173.544 208.515 182.984 1.00 53.67  ? 409 ASP B CG  1 
ATOM   4844 O OD1 . ASP B 1 409 ? 172.892 209.425 182.432 1.00 52.14  ? 409 ASP B OD1 1 
ATOM   4845 O OD2 . ASP B 1 409 ? 174.771 208.593 183.199 1.00 55.01  ? 409 ASP B OD2 1 
ATOM   4846 N N   . LEU B 1 410 ? 170.274 205.362 184.133 1.00 68.16  ? 410 LEU B N   1 
ATOM   4847 C CA  . LEU B 1 410 ? 169.619 204.058 184.135 1.00 66.71  ? 410 LEU B CA  1 
ATOM   4848 C C   . LEU B 1 410 ? 168.382 204.067 183.243 1.00 68.13  ? 410 LEU B C   1 
ATOM   4849 O O   . LEU B 1 410 ? 168.134 203.107 182.502 1.00 68.56  ? 410 LEU B O   1 
ATOM   4850 C CB  . LEU B 1 410 ? 169.260 203.658 185.568 1.00 70.95  ? 410 LEU B CB  1 
ATOM   4851 C CG  . LEU B 1 410 ? 168.805 202.225 185.866 1.00 72.02  ? 410 LEU B CG  1 
ATOM   4852 C CD1 . LEU B 1 410 ? 169.144 201.871 187.304 1.00 72.88  ? 410 LEU B CD1 1 
ATOM   4853 C CD2 . LEU B 1 410 ? 167.313 202.042 185.629 1.00 69.25  ? 410 LEU B CD2 1 
ATOM   4854 N N   . GLU B 1 411 ? 167.589 205.139 183.310 1.00 85.78  ? 411 GLU B N   1 
ATOM   4855 C CA  . GLU B 1 411 ? 166.420 205.254 182.439 1.00 88.87  ? 411 GLU B CA  1 
ATOM   4856 C C   . GLU B 1 411 ? 166.830 205.333 180.973 1.00 93.21  ? 411 GLU B C   1 
ATOM   4857 O O   . GLU B 1 411 ? 166.214 204.695 180.106 1.00 94.51  ? 411 GLU B O   1 
ATOM   4858 C CB  . GLU B 1 411 ? 165.586 206.472 182.833 1.00 87.04  ? 411 GLU B CB  1 
ATOM   4859 C CG  . GLU B 1 411 ? 164.096 206.309 182.578 1.00 90.65  ? 411 GLU B CG  1 
ATOM   4860 C CD  . GLU B 1 411 ? 163.464 205.250 183.462 1.00 92.51  ? 411 GLU B CD  1 
ATOM   4861 O OE1 . GLU B 1 411 ? 163.775 205.218 184.671 1.00 89.93  ? 411 GLU B OE1 1 
ATOM   4862 O OE2 . GLU B 1 411 ? 162.651 204.453 182.949 1.00 91.79  ? 411 GLU B OE2 1 
ATOM   4863 N N   . TYR B 1 412 ? 167.873 206.113 180.679 1.00 93.73  ? 412 TYR B N   1 
ATOM   4864 C CA  . TYR B 1 412 ? 168.391 206.160 179.318 1.00 91.29  ? 412 TYR B CA  1 
ATOM   4865 C C   . TYR B 1 412 ? 168.810 204.774 178.852 1.00 87.89  ? 412 TYR B C   1 
ATOM   4866 O O   . TYR B 1 412 ? 168.517 204.376 177.721 1.00 85.80  ? 412 TYR B O   1 
ATOM   4867 C CB  . TYR B 1 412 ? 169.571 207.125 179.232 1.00 88.50  ? 412 TYR B CB  1 
ATOM   4868 C CG  . TYR B 1 412 ? 170.267 207.097 177.894 1.00 87.80  ? 412 TYR B CG  1 
ATOM   4869 C CD1 . TYR B 1 412 ? 169.551 207.250 176.715 1.00 91.45  ? 412 TYR B CD1 1 
ATOM   4870 C CD2 . TYR B 1 412 ? 171.636 206.895 177.807 1.00 83.66  ? 412 TYR B CD2 1 
ATOM   4871 C CE1 . TYR B 1 412 ? 170.181 207.219 175.488 1.00 89.98  ? 412 TYR B CE1 1 
ATOM   4872 C CE2 . TYR B 1 412 ? 172.273 206.859 176.584 1.00 86.91  ? 412 TYR B CE2 1 
ATOM   4873 C CZ  . TYR B 1 412 ? 171.543 207.023 175.429 1.00 87.81  ? 412 TYR B CZ  1 
ATOM   4874 O OH  . TYR B 1 412 ? 172.179 206.990 174.211 1.00 86.18  ? 412 TYR B OH  1 
ATOM   4875 N N   . MET B 1 413 ? 169.484 204.020 179.722 1.00 89.87  ? 413 MET B N   1 
ATOM   4876 C CA  . MET B 1 413 ? 169.944 202.684 179.363 1.00 89.63  ? 413 MET B CA  1 
ATOM   4877 C C   . MET B 1 413 ? 168.777 201.740 179.097 1.00 94.35  ? 413 MET B C   1 
ATOM   4878 O O   . MET B 1 413 ? 168.812 200.960 178.140 1.00 98.30  ? 413 MET B O   1 
ATOM   4879 C CB  . MET B 1 413 ? 170.840 202.127 180.466 1.00 88.34  ? 413 MET B CB  1 
ATOM   4880 C CG  . MET B 1 413 ? 171.510 200.818 180.098 1.00 87.74  ? 413 MET B CG  1 
ATOM   4881 S SD  . MET B 1 413 ? 172.386 200.090 181.489 1.00 90.79  ? 413 MET B SD  1 
ATOM   4882 C CE  . MET B 1 413 ? 171.227 198.810 181.961 1.00 89.17  ? 413 MET B CE  1 
ATOM   4883 N N   . ILE B 1 414 ? 167.739 201.778 179.938 1.00 100.04 ? 414 ILE B N   1 
ATOM   4884 C CA  . ILE B 1 414 ? 166.653 200.816 179.756 1.00 100.17 ? 414 ILE B CA  1 
ATOM   4885 C C   . ILE B 1 414 ? 165.868 201.149 178.490 1.00 98.26  ? 414 ILE B C   1 
ATOM   4886 O O   . ILE B 1 414 ? 165.514 200.254 177.715 1.00 102.18 ? 414 ILE B O   1 
ATOM   4887 C CB  . ILE B 1 414 ? 165.742 200.743 181.001 1.00 101.75 ? 414 ILE B CB  1 
ATOM   4888 C CG1 . ILE B 1 414 ? 164.467 199.937 180.722 1.00 102.89 ? 414 ILE B CG1 1 
ATOM   4889 C CG2 . ILE B 1 414 ? 165.324 202.109 181.460 1.00 101.96 ? 414 ILE B CG2 1 
ATOM   4890 C CD1 . ILE B 1 414 ? 164.707 198.532 180.181 1.00 101.87 ? 414 ILE B CD1 1 
ATOM   4891 N N   . CYS B 1 415 ? 165.615 202.437 178.232 1.00 101.40 ? 415 CYS B N   1 
ATOM   4892 C CA  . CYS B 1 415 ? 164.936 202.800 176.988 1.00 108.84 ? 415 CYS B CA  1 
ATOM   4893 C C   . CYS B 1 415 ? 165.798 202.480 175.766 1.00 110.74 ? 415 CYS B C   1 
ATOM   4894 O O   . CYS B 1 415 ? 165.285 202.036 174.726 1.00 110.45 ? 415 CYS B O   1 
ATOM   4895 C CB  . CYS B 1 415 ? 164.553 204.279 177.013 1.00 109.37 ? 415 CYS B CB  1 
ATOM   4896 S SG  . CYS B 1 415 ? 165.847 205.389 176.432 1.00 111.46 ? 415 CYS B SG  1 
ATOM   4897 N N   . PHE B 1 416 ? 167.107 202.705 175.874 1.00 106.22 ? 416 PHE B N   1 
ATOM   4898 C CA  . PHE B 1 416 ? 168.023 202.422 174.778 1.00 104.29 ? 416 PHE B CA  1 
ATOM   4899 C C   . PHE B 1 416 ? 168.028 200.933 174.467 1.00 104.83 ? 416 PHE B C   1 
ATOM   4900 O O   . PHE B 1 416 ? 167.993 200.528 173.300 1.00 108.10 ? 416 PHE B O   1 
ATOM   4901 C CB  . PHE B 1 416 ? 169.420 202.908 175.170 1.00 105.80 ? 416 PHE B CB  1 
ATOM   4902 C CG  . PHE B 1 416 ? 170.367 203.065 174.020 1.00 106.90 ? 416 PHE B CG  1 
ATOM   4903 C CD1 . PHE B 1 416 ? 171.004 201.975 173.463 1.00 106.05 ? 416 PHE B CD1 1 
ATOM   4904 C CD2 . PHE B 1 416 ? 170.656 204.325 173.527 1.00 105.71 ? 416 PHE B CD2 1 
ATOM   4905 C CE1 . PHE B 1 416 ? 171.881 202.136 172.406 1.00 105.09 ? 416 PHE B CE1 1 
ATOM   4906 C CE2 . PHE B 1 416 ? 171.532 204.491 172.478 1.00 106.90 ? 416 PHE B CE2 1 
ATOM   4907 C CZ  . PHE B 1 416 ? 172.147 203.393 171.917 1.00 107.25 ? 416 PHE B CZ  1 
ATOM   4908 N N   . TYR B 1 417 ? 168.056 200.101 175.512 1.00 105.30 ? 417 TYR B N   1 
ATOM   4909 C CA  . TYR B 1 417 ? 167.956 198.657 175.328 1.00 107.05 ? 417 TYR B CA  1 
ATOM   4910 C C   . TYR B 1 417 ? 166.602 198.275 174.749 1.00 109.69 ? 417 TYR B C   1 
ATOM   4911 O O   . TYR B 1 417 ? 166.495 197.316 173.974 1.00 113.59 ? 417 TYR B O   1 
ATOM   4912 C CB  . TYR B 1 417 ? 168.213 197.935 176.655 1.00 107.42 ? 417 TYR B CB  1 
ATOM   4913 C CG  . TYR B 1 417 ? 169.685 197.765 176.966 1.00 110.72 ? 417 TYR B CG  1 
ATOM   4914 C CD1 . TYR B 1 417 ? 170.598 198.757 176.641 1.00 109.49 ? 417 TYR B CD1 1 
ATOM   4915 C CD2 . TYR B 1 417 ? 170.168 196.597 177.540 1.00 110.03 ? 417 TYR B CD2 1 
ATOM   4916 C CE1 . TYR B 1 417 ? 171.936 198.615 176.906 1.00 107.86 ? 417 TYR B CE1 1 
ATOM   4917 C CE2 . TYR B 1 417 ? 171.519 196.439 177.807 1.00 108.91 ? 417 TYR B CE2 1 
ATOM   4918 C CZ  . TYR B 1 417 ? 172.398 197.456 177.486 1.00 109.79 ? 417 TYR B CZ  1 
ATOM   4919 O OH  . TYR B 1 417 ? 173.746 197.323 177.740 1.00 112.33 ? 417 TYR B OH  1 
ATOM   4920 N N   . SER B 1 418 ? 165.557 199.016 175.117 1.00 111.78 ? 418 SER B N   1 
ATOM   4921 C CA  . SER B 1 418 ? 164.229 198.752 174.583 1.00 111.05 ? 418 SER B CA  1 
ATOM   4922 C C   . SER B 1 418 ? 164.179 198.973 173.078 1.00 113.63 ? 418 SER B C   1 
ATOM   4923 O O   . SER B 1 418 ? 163.515 198.215 172.362 1.00 114.72 ? 418 SER B O   1 
ATOM   4924 C CB  . SER B 1 418 ? 163.197 199.635 175.285 1.00 111.48 ? 418 SER B CB  1 
ATOM   4925 O OG  . SER B 1 418 ? 163.174 200.940 174.730 1.00 114.41 ? 418 SER B OG  1 
ATOM   4926 N N   . LEU B 1 419 ? 164.858 200.004 172.573 1.00 116.57 ? 419 LEU B N   1 
ATOM   4927 C CA  . LEU B 1 419 ? 164.616 200.351 171.175 1.00 116.41 ? 419 LEU B CA  1 
ATOM   4928 C C   . LEU B 1 419 ? 165.843 200.258 170.274 1.00 117.07 ? 419 LEU B C   1 
ATOM   4929 O O   . LEU B 1 419 ? 165.773 199.591 169.233 1.00 118.25 ? 419 LEU B O   1 
ATOM   4930 C CB  . LEU B 1 419 ? 163.975 201.750 171.089 1.00 114.89 ? 419 LEU B CB  1 
ATOM   4931 C CG  . LEU B 1 419 ? 164.162 202.666 169.877 1.00 117.16 ? 419 LEU B CG  1 
ATOM   4932 C CD1 . LEU B 1 419 ? 163.572 202.043 168.615 1.00 115.61 ? 419 LEU B CD1 1 
ATOM   4933 C CD2 . LEU B 1 419 ? 163.514 204.014 170.153 1.00 117.46 ? 419 LEU B CD2 1 
ATOM   4934 N N   . GLU B 1 420 ? 166.975 200.888 170.617 1.00 116.38 ? 420 GLU B N   1 
ATOM   4935 C CA  . GLU B 1 420 ? 167.977 201.193 169.594 1.00 116.01 ? 420 GLU B CA  1 
ATOM   4936 C C   . GLU B 1 420 ? 169.251 200.341 169.661 1.00 113.64 ? 420 GLU B C   1 
ATOM   4937 O O   . GLU B 1 420 ? 170.284 200.777 169.146 1.00 114.51 ? 420 GLU B O   1 
ATOM   4938 C CB  . GLU B 1 420 ? 168.395 202.665 169.644 1.00 115.75 ? 420 GLU B CB  1 
ATOM   4939 C CG  . GLU B 1 420 ? 168.612 203.234 171.028 1.00 116.29 ? 420 GLU B CG  1 
ATOM   4940 C CD  . GLU B 1 420 ? 167.599 204.274 171.432 1.00 115.91 ? 420 GLU B CD  1 
ATOM   4941 O OE1 . GLU B 1 420 ? 166.388 203.997 171.378 1.00 115.53 ? 420 GLU B OE1 1 
ATOM   4942 O OE2 . GLU B 1 420 ? 168.028 205.369 171.844 1.00 116.27 ? 420 GLU B OE2 1 
ATOM   4943 N N   . LEU B 1 421 ? 169.233 199.158 170.283 1.00 114.14 ? 421 LEU B N   1 
ATOM   4944 C CA  . LEU B 1 421 ? 170.413 198.296 170.177 1.00 118.78 ? 421 LEU B CA  1 
ATOM   4945 C C   . LEU B 1 421 ? 170.629 197.714 168.792 1.00 120.46 ? 421 LEU B C   1 
ATOM   4946 O O   . LEU B 1 421 ? 171.785 197.500 168.417 1.00 120.40 ? 421 LEU B O   1 
ATOM   4947 C CB  . LEU B 1 421 ? 170.394 197.142 171.183 1.00 117.69 ? 421 LEU B CB  1 
ATOM   4948 C CG  . LEU B 1 421 ? 170.868 197.370 172.619 1.00 117.11 ? 421 LEU B CG  1 
ATOM   4949 C CD1 . LEU B 1 421 ? 170.547 198.718 173.131 1.00 116.68 ? 421 LEU B CD1 1 
ATOM   4950 C CD2 . LEU B 1 421 ? 170.322 196.286 173.539 1.00 116.46 ? 421 LEU B CD2 1 
ATOM   4951 N N   . LYS B 1 422 ? 169.571 197.426 168.040 1.00 124.82 ? 422 LYS B N   1 
ATOM   4952 C CA  . LYS B 1 422 ? 169.704 196.680 166.792 1.00 124.30 ? 422 LYS B CA  1 
ATOM   4953 C C   . LYS B 1 422 ? 170.414 195.350 167.062 1.00 126.60 ? 422 LYS B C   1 
ATOM   4954 O O   . LYS B 1 422 ? 171.551 195.125 166.648 1.00 127.55 ? 422 LYS B O   1 
ATOM   4955 C CB  . LYS B 1 422 ? 170.460 197.497 165.737 1.00 123.49 ? 422 LYS B CB  1 
ATOM   4956 C CG  . LYS B 1 422 ? 169.598 198.203 164.701 1.00 122.93 ? 422 LYS B CG  1 
ATOM   4957 C CD  . LYS B 1 422 ? 170.469 198.741 163.569 1.00 124.19 ? 422 LYS B CD  1 
ATOM   4958 C CE  . LYS B 1 422 ? 169.767 199.818 162.748 1.00 124.77 ? 422 LYS B CE  1 
ATOM   4959 N NZ  . LYS B 1 422 ? 169.134 200.868 163.598 1.00 123.26 ? 422 LYS B NZ  1 
ATOM   4960 N N   . TRP B 1 423 ? 169.704 194.487 167.805 1.00 128.63 ? 423 TRP B N   1 
ATOM   4961 C CA  . TRP B 1 423 ? 170.280 193.242 168.318 1.00 128.41 ? 423 TRP B CA  1 
ATOM   4962 C C   . TRP B 1 423 ? 171.125 192.499 167.291 1.00 129.26 ? 423 TRP B C   1 
ATOM   4963 O O   . TRP B 1 423 ? 172.106 191.841 167.657 1.00 129.45 ? 423 TRP B O   1 
ATOM   4964 C CB  . TRP B 1 423 ? 169.171 192.317 168.827 1.00 129.11 ? 423 TRP B CB  1 
ATOM   4965 C CG  . TRP B 1 423 ? 168.207 192.955 169.780 1.00 130.83 ? 423 TRP B CG  1 
ATOM   4966 C CD1 . TRP B 1 423 ? 166.989 193.493 169.483 1.00 129.60 ? 423 TRP B CD1 1 
ATOM   4967 C CD2 . TRP B 1 423 ? 168.364 193.075 171.199 1.00 130.01 ? 423 TRP B CD2 1 
ATOM   4968 N NE1 . TRP B 1 423 ? 166.388 193.964 170.628 1.00 129.42 ? 423 TRP B NE1 1 
ATOM   4969 C CE2 . TRP B 1 423 ? 167.212 193.717 171.695 1.00 129.44 ? 423 TRP B CE2 1 
ATOM   4970 C CE3 . TRP B 1 423 ? 169.372 192.711 172.097 1.00 127.48 ? 423 TRP B CE3 1 
ATOM   4971 C CZ2 . TRP B 1 423 ? 167.040 194.002 173.048 1.00 127.80 ? 423 TRP B CZ2 1 
ATOM   4972 C CZ3 . TRP B 1 423 ? 169.200 192.993 173.439 1.00 125.31 ? 423 TRP B CZ3 1 
ATOM   4973 C CH2 . TRP B 1 423 ? 168.045 193.635 173.902 1.00 125.59 ? 423 TRP B CH2 1 
ATOM   4974 N N   . ASP B 1 424 ? 170.763 192.579 166.010 1.00 135.25 ? 424 ASP B N   1 
ATOM   4975 C CA  . ASP B 1 424 ? 171.547 191.902 164.982 1.00 135.97 ? 424 ASP B CA  1 
ATOM   4976 C C   . ASP B 1 424 ? 172.957 192.476 164.890 1.00 136.52 ? 424 ASP B C   1 
ATOM   4977 O O   . ASP B 1 424 ? 173.921 191.734 164.669 1.00 135.61 ? 424 ASP B O   1 
ATOM   4978 C CB  . ASP B 1 424 ? 170.832 191.995 163.635 1.00 137.64 ? 424 ASP B CB  1 
ATOM   4979 C CG  . ASP B 1 424 ? 169.364 191.620 163.729 1.00 137.34 ? 424 ASP B CG  1 
ATOM   4980 O OD1 . ASP B 1 424 ? 168.905 191.292 164.843 1.00 134.59 ? 424 ASP B OD1 1 
ATOM   4981 O OD2 . ASP B 1 424 ? 168.673 191.645 162.689 1.00 137.68 ? 424 ASP B OD2 1 
ATOM   4982 N N   . GLU B 1 425 ? 173.096 193.791 165.052 1.00 137.77 ? 425 GLU B N   1 
ATOM   4983 C CA  . GLU B 1 425 ? 174.403 194.430 164.948 1.00 137.21 ? 425 GLU B CA  1 
ATOM   4984 C C   . GLU B 1 425 ? 175.335 193.946 166.053 1.00 135.79 ? 425 GLU B C   1 
ATOM   4985 O O   . GLU B 1 425 ? 174.935 193.827 167.215 1.00 135.12 ? 425 GLU B O   1 
ATOM   4986 C CB  . GLU B 1 425 ? 174.252 195.950 165.015 1.00 136.95 ? 425 GLU B CB  1 
ATOM   4987 C CG  . GLU B 1 425 ? 175.470 196.723 164.534 1.00 137.62 ? 425 GLU B CG  1 
ATOM   4988 C CD  . GLU B 1 425 ? 175.232 198.221 164.497 1.00 139.41 ? 425 GLU B CD  1 
ATOM   4989 O OE1 . GLU B 1 425 ? 174.161 198.664 164.962 1.00 138.05 ? 425 GLU B OE1 1 
ATOM   4990 O OE2 . GLU B 1 425 ? 176.115 198.955 164.003 1.00 140.60 ? 425 GLU B OE2 1 
ATOM   4991 N N   . SER B 1 426 ? 176.587 193.661 165.683 1.00 132.53 ? 426 SER B N   1 
ATOM   4992 C CA  . SER B 1 426 ? 177.569 193.218 166.667 1.00 133.96 ? 426 SER B CA  1 
ATOM   4993 C C   . SER B 1 426 ? 178.006 194.356 167.581 1.00 133.37 ? 426 SER B C   1 
ATOM   4994 O O   . SER B 1 426 ? 178.320 194.122 168.753 1.00 132.76 ? 426 SER B O   1 
ATOM   4995 C CB  . SER B 1 426 ? 178.782 192.609 165.963 1.00 134.86 ? 426 SER B CB  1 
ATOM   4996 O OG  . SER B 1 426 ? 179.448 193.574 165.166 1.00 136.77 ? 426 SER B OG  1 
ATOM   4997 N N   . LYS B 1 427 ? 178.035 195.585 167.068 1.00 123.04 ? 427 LYS B N   1 
ATOM   4998 C CA  . LYS B 1 427 ? 178.418 196.747 167.859 1.00 123.96 ? 427 LYS B CA  1 
ATOM   4999 C C   . LYS B 1 427 ? 177.230 197.689 168.003 1.00 126.22 ? 427 LYS B C   1 
ATOM   5000 O O   . LYS B 1 427 ? 177.365 198.905 167.834 1.00 126.65 ? 427 LYS B O   1 
ATOM   5001 C CB  . LYS B 1 427 ? 179.605 197.471 167.220 1.00 121.93 ? 427 LYS B CB  1 
ATOM   5002 C CG  . LYS B 1 427 ? 180.706 196.549 166.727 1.00 122.53 ? 427 LYS B CG  1 
ATOM   5003 C CD  . LYS B 1 427 ? 181.309 195.756 167.873 1.00 122.96 ? 427 LYS B CD  1 
ATOM   5004 C CE  . LYS B 1 427 ? 182.083 196.662 168.815 1.00 124.31 ? 427 LYS B CE  1 
ATOM   5005 N NZ  . LYS B 1 427 ? 183.192 197.372 168.118 1.00 122.54 ? 427 LYS B NZ  1 
ATOM   5006 N N   . GLY B 1 428 ? 176.060 197.122 168.308 1.00 126.66 ? 428 GLY B N   1 
ATOM   5007 C CA  . GLY B 1 428 ? 174.840 197.913 168.331 1.00 123.99 ? 428 GLY B CA  1 
ATOM   5008 C C   . GLY B 1 428 ? 174.865 199.033 169.353 1.00 122.91 ? 428 GLY B C   1 
ATOM   5009 O O   . GLY B 1 428 ? 174.290 200.101 169.130 1.00 124.01 ? 428 GLY B O   1 
ATOM   5010 N N   . LEU B 1 429 ? 175.527 198.808 170.491 1.00 108.66 ? 429 LEU B N   1 
ATOM   5011 C CA  . LEU B 1 429 ? 175.616 199.847 171.510 1.00 110.56 ? 429 LEU B CA  1 
ATOM   5012 C C   . LEU B 1 429 ? 176.455 201.035 171.062 1.00 111.58 ? 429 LEU B C   1 
ATOM   5013 O O   . LEU B 1 429 ? 176.440 202.072 171.733 1.00 112.98 ? 429 LEU B O   1 
ATOM   5014 C CB  . LEU B 1 429 ? 176.180 199.269 172.810 1.00 110.64 ? 429 LEU B CB  1 
ATOM   5015 C CG  . LEU B 1 429 ? 177.689 199.356 173.045 1.00 110.97 ? 429 LEU B CG  1 
ATOM   5016 C CD1 . LEU B 1 429 ? 178.015 198.976 174.478 1.00 104.13 ? 429 LEU B CD1 1 
ATOM   5017 C CD2 . LEU B 1 429 ? 178.446 198.466 172.071 1.00 112.84 ? 429 LEU B CD2 1 
ATOM   5018 N N   . LEU B 1 430 ? 177.179 200.910 169.947 1.00 108.92 ? 430 LEU B N   1 
ATOM   5019 C CA  . LEU B 1 430 ? 177.966 201.992 169.363 1.00 108.98 ? 430 LEU B CA  1 
ATOM   5020 C C   . LEU B 1 430 ? 177.489 202.174 167.927 1.00 111.10 ? 430 LEU B C   1 
ATOM   5021 O O   . LEU B 1 430 ? 178.117 201.666 166.985 1.00 112.53 ? 430 LEU B O   1 
ATOM   5022 C CB  . LEU B 1 430 ? 179.462 201.686 169.414 1.00 106.24 ? 430 LEU B CB  1 
ATOM   5023 C CG  . LEU B 1 430 ? 180.157 201.787 170.773 1.00 108.87 ? 430 LEU B CG  1 
ATOM   5024 C CD1 . LEU B 1 430 ? 181.668 201.792 170.601 1.00 108.86 ? 430 LEU B CD1 1 
ATOM   5025 C CD2 . LEU B 1 430 ? 179.696 203.023 171.525 1.00 106.78 ? 430 LEU B CD2 1 
ATOM   5026 N N   . PRO B 1 431 ? 176.375 202.878 167.722 1.00 117.02 ? 431 PRO B N   1 
ATOM   5027 C CA  . PRO B 1 431 ? 175.834 203.021 166.365 1.00 118.11 ? 431 PRO B CA  1 
ATOM   5028 C C   . PRO B 1 431 ? 176.795 203.760 165.446 1.00 118.86 ? 431 PRO B C   1 
ATOM   5029 O O   . PRO B 1 431 ? 177.523 204.664 165.864 1.00 120.72 ? 431 PRO B O   1 
ATOM   5030 C CB  . PRO B 1 431 ? 174.539 203.815 166.578 1.00 118.17 ? 431 PRO B CB  1 
ATOM   5031 C CG  . PRO B 1 431 ? 174.721 204.503 167.888 1.00 115.15 ? 431 PRO B CG  1 
ATOM   5032 C CD  . PRO B 1 431 ? 175.564 203.589 168.723 1.00 114.35 ? 431 PRO B CD  1 
ATOM   5033 N N   . ASN B 1 432 ? 176.785 203.363 164.175 1.00 124.09 ? 432 ASN B N   1 
ATOM   5034 C CA  . ASN B 1 432 ? 177.673 203.922 163.165 1.00 126.10 ? 432 ASN B CA  1 
ATOM   5035 C C   . ASN B 1 432 ? 177.109 205.166 162.495 1.00 127.04 ? 432 ASN B C   1 
ATOM   5036 O O   . ASN B 1 432 ? 177.729 205.682 161.559 1.00 129.00 ? 432 ASN B O   1 
ATOM   5037 C CB  . ASN B 1 432 ? 177.987 202.868 162.098 1.00 126.79 ? 432 ASN B CB  1 
ATOM   5038 C CG  . ASN B 1 432 ? 179.399 202.986 161.560 1.00 126.93 ? 432 ASN B CG  1 
ATOM   5039 O OD1 . ASN B 1 432 ? 180.198 203.783 162.050 1.00 126.63 ? 432 ASN B OD1 1 
ATOM   5040 N ND2 . ASN B 1 432 ? 179.714 202.188 160.546 1.00 126.77 ? 432 ASN B ND2 1 
ATOM   5041 N N   . ASN B 1 433 ? 175.948 205.652 162.940 1.00 128.86 ? 433 ASN B N   1 
ATOM   5042 C CA  . ASN B 1 433 ? 175.365 206.845 162.335 1.00 130.89 ? 433 ASN B CA  1 
ATOM   5043 C C   . ASN B 1 433 ? 176.262 208.061 162.532 1.00 129.80 ? 433 ASN B C   1 
ATOM   5044 O O   . ASN B 1 433 ? 176.396 208.894 161.627 1.00 129.94 ? 433 ASN B O   1 
ATOM   5045 C CB  . ASN B 1 433 ? 173.977 207.105 162.921 1.00 132.68 ? 433 ASN B CB  1 
ATOM   5046 C CG  . ASN B 1 433 ? 173.084 205.881 162.869 1.00 133.07 ? 433 ASN B CG  1 
ATOM   5047 O OD1 . ASN B 1 433 ? 173.472 204.836 162.348 1.00 132.53 ? 433 ASN B OD1 1 
ATOM   5048 N ND2 . ASN B 1 433 ? 171.878 206.005 163.412 1.00 130.44 ? 433 ASN B ND2 1 
ATOM   5049 N N   . SER B 1 434 ? 176.867 208.187 163.714 1.00 127.37 ? 434 SER B N   1 
ATOM   5050 C CA  . SER B 1 434 ? 177.734 209.286 164.134 1.00 129.75 ? 434 SER B CA  1 
ATOM   5051 C C   . SER B 1 434 ? 176.977 210.596 164.302 1.00 132.02 ? 434 SER B C   1 
ATOM   5052 O O   . SER B 1 434 ? 177.583 211.599 164.699 1.00 132.24 ? 434 SER B O   1 
ATOM   5053 C CB  . SER B 1 434 ? 178.915 209.509 163.177 1.00 127.94 ? 434 SER B CB  1 
ATOM   5054 O OG  . SER B 1 434 ? 179.755 210.552 163.639 1.00 127.08 ? 434 SER B OG  1 
ATOM   5055 N N   . GLU B 1 435 ? 175.678 210.626 164.016 1.00 140.78 ? 435 GLU B N   1 
ATOM   5056 C CA  . GLU B 1 435 ? 174.836 211.793 164.233 1.00 139.63 ? 435 GLU B CA  1 
ATOM   5057 C C   . GLU B 1 435 ? 173.709 211.404 165.176 1.00 138.83 ? 435 GLU B C   1 
ATOM   5058 O O   . GLU B 1 435 ? 172.999 210.423 164.929 1.00 140.31 ? 435 GLU B O   1 
ATOM   5059 C CB  . GLU B 1 435 ? 174.275 212.325 162.911 1.00 139.48 ? 435 GLU B CB  1 
ATOM   5060 C CG  . GLU B 1 435 ? 175.338 212.630 161.868 1.00 139.47 ? 435 GLU B CG  1 
ATOM   5061 C CD  . GLU B 1 435 ? 174.753 213.185 160.584 1.00 140.09 ? 435 GLU B CD  1 
ATOM   5062 O OE1 . GLU B 1 435 ? 173.519 213.360 160.518 1.00 140.41 ? 435 GLU B OE1 1 
ATOM   5063 O OE2 . GLU B 1 435 ? 175.529 213.445 159.640 1.00 140.51 ? 435 GLU B OE2 1 
ATOM   5064 N N   . GLU B 1 436 ? 173.546 212.170 166.251 1.00 119.95 ? 436 GLU B N   1 
ATOM   5065 C CA  . GLU B 1 436 ? 172.588 211.830 167.298 1.00 120.84 ? 436 GLU B CA  1 
ATOM   5066 C C   . GLU B 1 436 ? 171.192 212.262 166.869 1.00 122.39 ? 436 GLU B C   1 
ATOM   5067 O O   . GLU B 1 436 ? 170.876 213.456 166.859 1.00 122.53 ? 436 GLU B O   1 
ATOM   5068 C CB  . GLU B 1 436 ? 172.989 212.487 168.615 1.00 123.23 ? 436 GLU B CB  1 
ATOM   5069 C CG  . GLU B 1 436 ? 174.459 212.324 168.958 1.00 124.00 ? 436 GLU B CG  1 
ATOM   5070 C CD  . GLU B 1 436 ? 174.757 212.642 170.409 1.00 123.39 ? 436 GLU B CD  1 
ATOM   5071 O OE1 . GLU B 1 436 ? 174.402 213.749 170.863 1.00 121.27 ? 436 GLU B OE1 1 
ATOM   5072 O OE2 . GLU B 1 436 ? 175.346 211.782 171.096 1.00 121.07 ? 436 GLU B OE2 1 
ATOM   5073 N N   . SER B 1 437 ? 170.353 211.285 166.514 1.00 133.15 ? 437 SER B N   1 
ATOM   5074 C CA  . SER B 1 437 ? 168.959 211.535 166.167 1.00 133.77 ? 437 SER B CA  1 
ATOM   5075 C C   . SER B 1 437 ? 168.037 210.474 166.758 1.00 133.07 ? 437 SER B C   1 
ATOM   5076 O O   . SER B 1 437 ? 166.898 210.326 166.301 1.00 132.61 ? 437 SER B O   1 
ATOM   5077 C CB  . SER B 1 437 ? 168.780 211.606 164.648 1.00 132.14 ? 437 SER B CB  1 
ATOM   5078 O OG  . SER B 1 437 ? 169.200 210.404 164.028 1.00 134.54 ? 437 SER B OG  1 
ATOM   5079 N N   . GLY B 1 438 ? 168.506 209.734 167.760 1.00 128.53 ? 438 GLY B N   1 
ATOM   5080 C CA  . GLY B 1 438 ? 167.697 208.689 168.348 1.00 129.80 ? 438 GLY B CA  1 
ATOM   5081 C C   . GLY B 1 438 ? 166.529 209.233 169.148 1.00 130.85 ? 438 GLY B C   1 
ATOM   5082 O O   . GLY B 1 438 ? 166.516 210.380 169.598 1.00 129.68 ? 438 GLY B O   1 
ATOM   5083 N N   . ILE B 1 439 ? 165.521 208.376 169.320 1.00 131.66 ? 439 ILE B N   1 
ATOM   5084 C CA  . ILE B 1 439 ? 164.332 208.766 170.069 1.00 132.30 ? 439 ILE B CA  1 
ATOM   5085 C C   . ILE B 1 439 ? 164.668 208.969 171.541 1.00 130.99 ? 439 ILE B C   1 
ATOM   5086 O O   . ILE B 1 439 ? 164.124 209.865 172.197 1.00 131.61 ? 439 ILE B O   1 
ATOM   5087 C CB  . ILE B 1 439 ? 163.216 207.722 169.880 1.00 131.13 ? 439 ILE B CB  1 
ATOM   5088 C CG1 . ILE B 1 439 ? 162.998 207.442 168.392 1.00 130.07 ? 439 ILE B CG1 1 
ATOM   5089 C CG2 . ILE B 1 439 ? 161.924 208.196 170.527 1.00 132.25 ? 439 ILE B CG2 1 
ATOM   5090 C CD1 . ILE B 1 439 ? 162.578 208.659 167.598 1.00 131.26 ? 439 ILE B CD1 1 
ATOM   5091 N N   . CYS B 1 440 ? 165.557 208.139 172.087 1.00 122.88 ? 440 CYS B N   1 
ATOM   5092 C CA  . CYS B 1 440 ? 165.936 208.281 173.488 1.00 122.38 ? 440 CYS B CA  1 
ATOM   5093 C C   . CYS B 1 440 ? 166.875 209.458 173.717 1.00 122.58 ? 440 CYS B C   1 
ATOM   5094 O O   . CYS B 1 440 ? 166.877 210.034 174.811 1.00 120.10 ? 440 CYS B O   1 
ATOM   5095 C CB  . CYS B 1 440 ? 166.581 206.993 173.997 1.00 124.49 ? 440 CYS B CB  1 
ATOM   5096 S SG  . CYS B 1 440 ? 165.410 205.708 174.476 1.00 131.04 ? 440 CYS B SG  1 
ATOM   5097 N N   . HIS B 1 441 ? 167.685 209.820 172.717 1.00 121.89 ? 441 HIS B N   1 
ATOM   5098 C CA  . HIS B 1 441 ? 168.581 210.962 172.873 1.00 120.71 ? 441 HIS B CA  1 
ATOM   5099 C C   . HIS B 1 441 ? 167.798 212.244 173.125 1.00 121.57 ? 441 HIS B C   1 
ATOM   5100 O O   . HIS B 1 441 ? 168.158 213.039 174.001 1.00 121.51 ? 441 HIS B O   1 
ATOM   5101 C CB  . HIS B 1 441 ? 169.467 211.115 171.638 1.00 121.32 ? 441 HIS B CB  1 
ATOM   5102 C CG  . HIS B 1 441 ? 170.416 212.270 171.718 1.00 120.43 ? 441 HIS B CG  1 
ATOM   5103 N ND1 . HIS B 1 441 ? 170.431 213.287 170.789 1.00 121.23 ? 441 HIS B ND1 1 
ATOM   5104 C CD2 . HIS B 1 441 ? 171.381 212.570 172.619 1.00 118.15 ? 441 HIS B CD2 1 
ATOM   5105 C CE1 . HIS B 1 441 ? 171.363 214.165 171.114 1.00 121.17 ? 441 HIS B CE1 1 
ATOM   5106 N NE2 . HIS B 1 441 ? 171.956 213.752 172.220 1.00 118.60 ? 441 HIS B NE2 1 
ATOM   5107 N N   . LYS B 1 442 ? 166.728 212.463 172.367 1.00 124.81 ? 442 LYS B N   1 
ATOM   5108 C CA  . LYS B 1 442 ? 165.815 213.557 172.653 1.00 124.88 ? 442 LYS B CA  1 
ATOM   5109 C C   . LYS B 1 442 ? 164.874 213.155 173.780 1.00 124.97 ? 442 LYS B C   1 
ATOM   5110 O O   . LYS B 1 442 ? 164.342 212.042 173.800 1.00 126.31 ? 442 LYS B O   1 
ATOM   5111 C CB  . LYS B 1 442 ? 165.023 213.940 171.401 1.00 123.61 ? 442 LYS B CB  1 
ATOM   5112 C CG  . LYS B 1 442 ? 164.268 212.789 170.755 1.00 124.02 ? 442 LYS B CG  1 
ATOM   5113 C CD  . LYS B 1 442 ? 163.693 213.189 169.406 1.00 124.14 ? 442 LYS B CD  1 
ATOM   5114 C CE  . LYS B 1 442 ? 164.674 212.902 168.280 1.00 123.71 ? 442 LYS B CE  1 
ATOM   5115 N NZ  . LYS B 1 442 ? 164.102 213.238 166.947 1.00 123.53 ? 442 LYS B NZ  1 
ATOM   5116 N N   . TYR B 1 443 ? 164.682 214.060 174.733 1.00 123.83 ? 443 TYR B N   1 
ATOM   5117 C CA  . TYR B 1 443 ? 163.857 213.800 175.907 1.00 123.81 ? 443 TYR B CA  1 
ATOM   5118 C C   . TYR B 1 443 ? 162.501 214.489 175.788 1.00 124.73 ? 443 TYR B C   1 
ATOM   5119 O O   . TYR B 1 443 ? 161.949 214.994 176.767 1.00 122.73 ? 443 TYR B O   1 
ATOM   5120 C CB  . TYR B 1 443 ? 164.587 214.223 177.178 1.00 123.05 ? 443 TYR B CB  1 
ATOM   5121 C CG  . TYR B 1 443 ? 166.033 213.773 177.211 1.00 124.38 ? 443 TYR B CG  1 
ATOM   5122 C CD1 . TYR B 1 443 ? 166.369 212.438 177.030 1.00 124.51 ? 443 TYR B CD1 1 
ATOM   5123 C CD2 . TYR B 1 443 ? 167.061 214.682 177.418 1.00 125.08 ? 443 TYR B CD2 1 
ATOM   5124 C CE1 . TYR B 1 443 ? 167.688 212.024 177.055 1.00 122.90 ? 443 TYR B CE1 1 
ATOM   5125 C CE2 . TYR B 1 443 ? 168.381 214.277 177.442 1.00 125.51 ? 443 TYR B CE2 1 
ATOM   5126 C CZ  . TYR B 1 443 ? 168.689 212.947 177.262 1.00 124.05 ? 443 TYR B CZ  1 
ATOM   5127 O OH  . TYR B 1 443 ? 170.003 212.540 177.289 1.00 123.64 ? 443 TYR B OH  1 
ATOM   5128 N N   . THR B 1 444 ? 161.955 214.512 174.569 1.00 137.28 ? 444 THR B N   1 
ATOM   5129 C CA  . THR B 1 444 ? 160.641 215.097 174.332 1.00 138.34 ? 444 THR B CA  1 
ATOM   5130 C C   . THR B 1 444 ? 159.519 214.268 174.944 1.00 137.85 ? 444 THR B C   1 
ATOM   5131 O O   . THR B 1 444 ? 158.426 214.798 175.171 1.00 136.47 ? 444 THR B O   1 
ATOM   5132 C CB  . THR B 1 444 ? 160.406 215.261 172.828 1.00 138.56 ? 444 THR B CB  1 
ATOM   5133 O OG1 . THR B 1 444 ? 161.618 215.698 172.199 1.00 138.15 ? 444 THR B OG1 1 
ATOM   5134 C CG2 . THR B 1 444 ? 159.311 216.285 172.560 1.00 136.85 ? 444 THR B CG2 1 
ATOM   5135 N N   . TYR B 1 445 ? 159.763 212.983 175.217 1.00 132.06 ? 445 TYR B N   1 
ATOM   5136 C CA  . TYR B 1 445 ? 158.726 212.141 175.804 1.00 130.58 ? 445 TYR B CA  1 
ATOM   5137 C C   . TYR B 1 445 ? 158.314 212.653 177.178 1.00 131.02 ? 445 TYR B C   1 
ATOM   5138 O O   . TYR B 1 445 ? 157.129 212.626 177.530 1.00 132.34 ? 445 TYR B O   1 
ATOM   5139 C CB  . TYR B 1 445 ? 159.211 210.694 175.892 1.00 129.88 ? 445 TYR B CB  1 
ATOM   5140 C CG  . TYR B 1 445 ? 158.118 209.665 175.701 1.00 133.20 ? 445 TYR B CG  1 
ATOM   5141 C CD1 . TYR B 1 445 ? 156.780 210.035 175.698 1.00 133.46 ? 445 TYR B CD1 1 
ATOM   5142 C CD2 . TYR B 1 445 ? 158.426 208.322 175.525 1.00 133.02 ? 445 TYR B CD2 1 
ATOM   5143 C CE1 . TYR B 1 445 ? 155.779 209.098 175.524 1.00 133.32 ? 445 TYR B CE1 1 
ATOM   5144 C CE2 . TYR B 1 445 ? 157.432 207.377 175.351 1.00 132.05 ? 445 TYR B CE2 1 
ATOM   5145 C CZ  . TYR B 1 445 ? 156.110 207.771 175.351 1.00 133.42 ? 445 TYR B CZ  1 
ATOM   5146 O OH  . TYR B 1 445 ? 155.117 206.834 175.177 1.00 133.31 ? 445 TYR B OH  1 
ATOM   5147 N N   . GLY B 1 446 ? 159.277 213.123 177.967 1.00 113.56 ? 446 GLY B N   1 
ATOM   5148 C CA  . GLY B 1 446 ? 159.006 213.670 179.277 1.00 112.39 ? 446 GLY B CA  1 
ATOM   5149 C C   . GLY B 1 446 ? 159.333 212.753 180.435 1.00 110.23 ? 446 GLY B C   1 
ATOM   5150 O O   . GLY B 1 446 ? 159.321 213.212 181.584 1.00 105.93 ? 446 GLY B O   1 
ATOM   5151 N N   . VAL B 1 447 ? 159.622 211.475 180.174 1.00 101.40 ? 447 VAL B N   1 
ATOM   5152 C CA  . VAL B 1 447 ? 159.975 210.564 181.259 1.00 96.42  ? 447 VAL B CA  1 
ATOM   5153 C C   . VAL B 1 447 ? 161.292 210.975 181.903 1.00 96.73  ? 447 VAL B C   1 
ATOM   5154 O O   . VAL B 1 447 ? 161.513 210.726 183.096 1.00 99.83  ? 447 VAL B O   1 
ATOM   5155 C CB  . VAL B 1 447 ? 160.010 209.107 180.752 1.00 97.22  ? 447 VAL B CB  1 
ATOM   5156 C CG1 . VAL B 1 447 ? 161.353 208.777 180.114 1.00 96.82  ? 447 VAL B CG1 1 
ATOM   5157 C CG2 . VAL B 1 447 ? 159.709 208.145 181.890 1.00 97.88  ? 447 VAL B CG2 1 
ATOM   5158 N N   . ARG B 1 448 ? 162.177 211.620 181.136 1.00 93.56  ? 448 ARG B N   1 
ATOM   5159 C CA  . ARG B 1 448 ? 163.428 212.117 181.699 1.00 92.94  ? 448 ARG B CA  1 
ATOM   5160 C C   . ARG B 1 448 ? 163.161 213.121 182.808 1.00 96.47  ? 448 ARG B C   1 
ATOM   5161 O O   . ARG B 1 448 ? 163.796 213.074 183.870 1.00 96.72  ? 448 ARG B O   1 
ATOM   5162 C CB  . ARG B 1 448 ? 164.284 212.748 180.602 1.00 93.16  ? 448 ARG B CB  1 
ATOM   5163 C CG  . ARG B 1 448 ? 165.627 213.271 181.083 1.00 93.28  ? 448 ARG B CG  1 
ATOM   5164 C CD  . ARG B 1 448 ? 166.632 212.145 181.219 1.00 96.61  ? 448 ARG B CD  1 
ATOM   5165 N NE  . ARG B 1 448 ? 166.508 211.179 180.135 1.00 97.18  ? 448 ARG B NE  1 
ATOM   5166 C CZ  . ARG B 1 448 ? 167.376 210.207 179.895 1.00 92.93  ? 448 ARG B CZ  1 
ATOM   5167 N NH1 . ARG B 1 448 ? 168.455 210.043 180.643 1.00 90.79  ? 448 ARG B NH1 1 
ATOM   5168 N NH2 . ARG B 1 448 ? 167.157 209.378 178.879 1.00 92.58  ? 448 ARG B NH2 1 
ATOM   5169 N N   . ALA B 1 449 ? 162.204 214.024 182.589 1.00 82.71  ? 449 ALA B N   1 
ATOM   5170 C CA  . ALA B 1 449 ? 161.857 214.995 183.617 1.00 76.38  ? 449 ALA B CA  1 
ATOM   5171 C C   . ALA B 1 449 ? 161.377 214.300 184.883 1.00 76.62  ? 449 ALA B C   1 
ATOM   5172 O O   . ALA B 1 449 ? 161.811 214.635 185.991 1.00 77.45  ? 449 ALA B O   1 
ATOM   5173 C CB  . ALA B 1 449 ? 160.793 215.959 183.089 1.00 79.98  ? 449 ALA B CB  1 
ATOM   5174 N N   . ILE B 1 450 ? 160.502 213.302 184.737 1.00 84.31  ? 450 ILE B N   1 
ATOM   5175 C CA  . ILE B 1 450 ? 159.969 212.624 185.915 1.00 88.41  ? 450 ILE B CA  1 
ATOM   5176 C C   . ILE B 1 450 ? 161.088 211.932 186.683 1.00 88.75  ? 450 ILE B C   1 
ATOM   5177 O O   . ILE B 1 450 ? 161.266 212.169 187.884 1.00 89.34  ? 450 ILE B O   1 
ATOM   5178 C CB  . ILE B 1 450 ? 158.854 211.640 185.520 1.00 88.45  ? 450 ILE B CB  1 
ATOM   5179 C CG1 . ILE B 1 450 ? 158.058 212.183 184.333 1.00 87.93  ? 450 ILE B CG1 1 
ATOM   5180 C CG2 . ILE B 1 450 ? 157.930 211.381 186.701 1.00 87.15  ? 450 ILE B CG2 1 
ATOM   5181 C CD1 . ILE B 1 450 ? 157.243 211.134 183.606 1.00 88.49  ? 450 ILE B CD1 1 
ATOM   5182 N N   . VAL B 1 451 ? 161.895 211.117 185.993 1.00 74.16  ? 451 VAL B N   1 
ATOM   5183 C CA  . VAL B 1 451 ? 162.946 210.384 186.691 1.00 68.79  ? 451 VAL B CA  1 
ATOM   5184 C C   . VAL B 1 451 ? 163.971 211.336 187.279 1.00 71.33  ? 451 VAL B C   1 
ATOM   5185 O O   . VAL B 1 451 ? 164.681 210.975 188.223 1.00 81.85  ? 451 VAL B O   1 
ATOM   5186 C CB  . VAL B 1 451 ? 163.639 209.350 185.774 1.00 74.60  ? 451 VAL B CB  1 
ATOM   5187 C CG1 . VAL B 1 451 ? 162.712 208.177 185.493 1.00 78.21  ? 451 VAL B CG1 1 
ATOM   5188 C CG2 . VAL B 1 451 ? 164.150 209.991 184.500 1.00 73.83  ? 451 VAL B CG2 1 
ATOM   5189 N N   . GLN B 1 452 ? 164.071 212.553 186.743 1.00 66.18  ? 452 GLN B N   1 
ATOM   5190 C CA  . GLN B 1 452 ? 164.948 213.542 187.353 1.00 69.95  ? 452 GLN B CA  1 
ATOM   5191 C C   . GLN B 1 452 ? 164.314 214.138 188.608 1.00 74.69  ? 452 GLN B C   1 
ATOM   5192 O O   . GLN B 1 452 ? 165.025 214.539 189.536 1.00 71.48  ? 452 GLN B O   1 
ATOM   5193 C CB  . GLN B 1 452 ? 165.290 214.623 186.328 1.00 72.06  ? 452 GLN B CB  1 
ATOM   5194 C CG  . GLN B 1 452 ? 166.071 215.796 186.874 1.00 71.44  ? 452 GLN B CG  1 
ATOM   5195 C CD  . GLN B 1 452 ? 167.083 216.316 185.872 1.00 75.31  ? 452 GLN B CD  1 
ATOM   5196 O OE1 . GLN B 1 452 ? 166.755 216.566 184.711 1.00 78.75  ? 452 GLN B OE1 1 
ATOM   5197 N NE2 . GLN B 1 452 ? 168.332 216.433 186.303 1.00 69.63  ? 452 GLN B NE2 1 
ATOM   5198 N N   . CYS B 1 453 ? 162.977 214.211 188.657 1.00 74.52  ? 453 CYS B N   1 
ATOM   5199 C CA  . CYS B 1 453 ? 162.318 214.755 189.845 1.00 66.14  ? 453 CYS B CA  1 
ATOM   5200 C C   . CYS B 1 453 ? 162.091 213.740 190.965 1.00 70.44  ? 453 CYS B C   1 
ATOM   5201 O O   . CYS B 1 453 ? 161.823 214.163 192.095 1.00 72.44  ? 453 CYS B O   1 
ATOM   5202 C CB  . CYS B 1 453 ? 160.966 215.392 189.500 1.00 64.79  ? 453 CYS B CB  1 
ATOM   5203 S SG  . CYS B 1 453 ? 160.903 216.464 188.053 1.00 83.51  ? 453 CYS B SG  1 
ATOM   5204 N N   . ILE B 1 454 ? 162.168 212.428 190.696 1.00 70.59  ? 454 ILE B N   1 
ATOM   5205 C CA  . ILE B 1 454 ? 162.052 211.448 191.792 1.00 68.42  ? 454 ILE B CA  1 
ATOM   5206 C C   . ILE B 1 454 ? 162.995 211.725 192.959 1.00 68.18  ? 454 ILE B C   1 
ATOM   5207 O O   . ILE B 1 454 ? 162.546 211.652 194.113 1.00 73.21  ? 454 ILE B O   1 
ATOM   5208 C CB  . ILE B 1 454 ? 162.177 210.011 191.258 1.00 65.05  ? 454 ILE B CB  1 
ATOM   5209 C CG1 . ILE B 1 454 ? 161.535 209.805 189.887 1.00 72.07  ? 454 ILE B CG1 1 
ATOM   5210 C CG2 . ILE B 1 454 ? 161.575 209.027 192.253 1.00 64.28  ? 454 ILE B CG2 1 
ATOM   5211 C CD1 . ILE B 1 454 ? 160.103 210.342 189.805 1.00 76.28  ? 454 ILE B CD1 1 
ATOM   5212 N N   . PRO B 1 455 ? 164.286 212.019 192.760 1.00 58.64  ? 455 PRO B N   1 
ATOM   5213 C CA  . PRO B 1 455 ? 165.122 212.361 193.923 1.00 53.75  ? 455 PRO B CA  1 
ATOM   5214 C C   . PRO B 1 455 ? 164.616 213.567 194.696 1.00 62.62  ? 455 PRO B C   1 
ATOM   5215 O O   . PRO B 1 455 ? 164.739 213.599 195.927 1.00 52.20  ? 455 PRO B O   1 
ATOM   5216 C CB  . PRO B 1 455 ? 166.505 212.615 193.305 1.00 49.76  ? 455 PRO B CB  1 
ATOM   5217 C CG  . PRO B 1 455 ? 166.249 212.860 191.868 1.00 55.22  ? 455 PRO B CG  1 
ATOM   5218 C CD  . PRO B 1 455 ? 165.079 212.001 191.518 1.00 56.19  ? 455 PRO B CD  1 
ATOM   5219 N N   . ALA B 1 456 ? 164.050 214.564 194.014 1.00 71.81  ? 456 ALA B N   1 
ATOM   5220 C CA  . ALA B 1 456 ? 163.421 215.685 194.704 1.00 63.43  ? 456 ALA B CA  1 
ATOM   5221 C C   . ALA B 1 456 ? 162.042 215.329 195.239 1.00 61.94  ? 456 ALA B C   1 
ATOM   5222 O O   . ALA B 1 456 ? 161.640 215.836 196.291 1.00 69.65  ? 456 ALA B O   1 
ATOM   5223 C CB  . ALA B 1 456 ? 163.316 216.884 193.767 1.00 61.78  ? 456 ALA B CB  1 
ATOM   5224 N N   . TRP B 1 457 ? 161.306 214.484 194.515 1.00 61.13  ? 457 TRP B N   1 
ATOM   5225 C CA  . TRP B 1 457 ? 159.970 214.075 194.937 1.00 62.94  ? 457 TRP B CA  1 
ATOM   5226 C C   . TRP B 1 457 ? 160.013 213.344 196.274 1.00 68.28  ? 457 TRP B C   1 
ATOM   5227 O O   . TRP B 1 457 ? 159.192 213.606 197.168 1.00 77.57  ? 457 TRP B O   1 
ATOM   5228 C CB  . TRP B 1 457 ? 159.366 213.203 193.834 1.00 69.11  ? 457 TRP B CB  1 
ATOM   5229 C CG  . TRP B 1 457 ? 157.986 212.682 194.044 1.00 70.51  ? 457 TRP B CG  1 
ATOM   5230 C CD1 . TRP B 1 457 ? 156.816 213.333 193.787 1.00 71.33  ? 457 TRP B CD1 1 
ATOM   5231 C CD2 . TRP B 1 457 ? 157.626 211.364 194.470 1.00 71.10  ? 457 TRP B CD2 1 
ATOM   5232 N NE1 . TRP B 1 457 ? 155.748 212.515 194.067 1.00 70.75  ? 457 TRP B NE1 1 
ATOM   5233 C CE2 . TRP B 1 457 ? 156.220 211.297 194.480 1.00 71.71  ? 457 TRP B CE2 1 
ATOM   5234 C CE3 . TRP B 1 457 ? 158.358 210.237 194.859 1.00 72.77  ? 457 TRP B CE3 1 
ATOM   5235 C CZ2 . TRP B 1 457 ? 155.530 210.152 194.874 1.00 72.54  ? 457 TRP B CZ2 1 
ATOM   5236 C CZ3 . TRP B 1 457 ? 157.671 209.101 195.246 1.00 74.17  ? 457 TRP B CZ3 1 
ATOM   5237 C CH2 . TRP B 1 457 ? 156.271 209.067 195.251 1.00 73.47  ? 457 TRP B CH2 1 
ATOM   5238 N N   . LEU B 1 458 ? 160.982 212.438 196.435 1.00 64.10  ? 458 LEU B N   1 
ATOM   5239 C CA  . LEU B 1 458 ? 161.119 211.703 197.688 1.00 62.38  ? 458 LEU B CA  1 
ATOM   5240 C C   . LEU B 1 458 ? 161.420 212.645 198.846 1.00 64.09  ? 458 LEU B C   1 
ATOM   5241 O O   . LEU B 1 458 ? 160.824 212.530 199.921 1.00 69.18  ? 458 LEU B O   1 
ATOM   5242 C CB  . LEU B 1 458 ? 162.212 210.643 197.558 1.00 61.48  ? 458 LEU B CB  1 
ATOM   5243 C CG  . LEU B 1 458 ? 161.989 209.555 196.508 1.00 66.17  ? 458 LEU B CG  1 
ATOM   5244 C CD1 . LEU B 1 458 ? 163.318 209.024 195.996 1.00 64.61  ? 458 LEU B CD1 1 
ATOM   5245 C CD2 . LEU B 1 458 ? 161.139 208.429 197.073 1.00 69.24  ? 458 LEU B CD2 1 
ATOM   5246 N N   . ARG B 1 459 ? 162.342 213.590 198.643 1.00 57.39  ? 459 ARG B N   1 
ATOM   5247 C CA  . ARG B 1 459 ? 162.670 214.546 199.698 1.00 58.35  ? 459 ARG B CA  1 
ATOM   5248 C C   . ARG B 1 459 ? 161.477 215.427 200.044 1.00 60.96  ? 459 ARG B C   1 
ATOM   5249 O O   . ARG B 1 459 ? 161.221 215.702 201.223 1.00 66.34  ? 459 ARG B O   1 
ATOM   5250 C CB  . ARG B 1 459 ? 163.862 215.404 199.274 1.00 57.20  ? 459 ARG B CB  1 
ATOM   5251 C CG  . ARG B 1 459 ? 165.197 214.929 199.815 1.00 54.33  ? 459 ARG B CG  1 
ATOM   5252 C CD  . ARG B 1 459 ? 165.085 214.551 201.282 1.00 42.78  ? 459 ARG B CD  1 
ATOM   5253 N NE  . ARG B 1 459 ? 165.117 215.714 202.159 1.00 39.42  ? 459 ARG B NE  1 
ATOM   5254 C CZ  . ARG B 1 459 ? 164.740 215.700 203.430 1.00 47.56  ? 459 ARG B CZ  1 
ATOM   5255 N NH1 . ARG B 1 459 ? 164.280 214.600 204.002 1.00 53.94  ? 459 ARG B NH1 1 
ATOM   5256 N NH2 . ARG B 1 459 ? 164.831 216.816 204.147 1.00 50.93  ? 459 ARG B NH2 1 
ATOM   5257 N N   . PHE B 1 460 ? 160.739 215.879 199.029 1.00 51.99  ? 460 PHE B N   1 
ATOM   5258 C CA  . PHE B 1 460 ? 159.579 216.731 199.263 1.00 53.14  ? 460 PHE B CA  1 
ATOM   5259 C C   . PHE B 1 460 ? 158.538 216.014 200.112 1.00 55.88  ? 460 PHE B C   1 
ATOM   5260 O O   . PHE B 1 460 ? 158.055 216.554 201.117 1.00 64.47  ? 460 PHE B O   1 
ATOM   5261 C CB  . PHE B 1 460 ? 158.995 217.166 197.916 1.00 60.13  ? 460 PHE B CB  1 
ATOM   5262 C CG  . PHE B 1 460 ? 157.680 217.883 198.015 1.00 60.72  ? 460 PHE B CG  1 
ATOM   5263 C CD1 . PHE B 1 460 ? 157.631 219.225 198.349 1.00 63.13  ? 460 PHE B CD1 1 
ATOM   5264 C CD2 . PHE B 1 460 ? 156.494 217.221 197.746 1.00 61.26  ? 460 PHE B CD2 1 
ATOM   5265 C CE1 . PHE B 1 460 ? 156.422 219.889 198.429 1.00 64.98  ? 460 PHE B CE1 1 
ATOM   5266 C CE2 . PHE B 1 460 ? 155.283 217.880 197.825 1.00 63.19  ? 460 PHE B CE2 1 
ATOM   5267 C CZ  . PHE B 1 460 ? 155.248 219.215 198.167 1.00 64.79  ? 460 PHE B CZ  1 
ATOM   5268 N N   . ILE B 1 461 ? 158.196 214.778 199.739 1.00 56.97  ? 461 ILE B N   1 
ATOM   5269 C CA  . ILE B 1 461 ? 157.186 214.057 200.508 1.00 60.60  ? 461 ILE B CA  1 
ATOM   5270 C C   . ILE B 1 461 ? 157.718 213.636 201.876 1.00 63.85  ? 461 ILE B C   1 
ATOM   5271 O O   . ILE B 1 461 ? 156.962 213.605 202.855 1.00 66.21  ? 461 ILE B O   1 
ATOM   5272 C CB  . ILE B 1 461 ? 156.645 212.868 199.695 1.00 62.73  ? 461 ILE B CB  1 
ATOM   5273 C CG1 . ILE B 1 461 ? 155.720 213.392 198.600 1.00 64.82  ? 461 ILE B CG1 1 
ATOM   5274 C CG2 . ILE B 1 461 ? 155.905 211.883 200.578 1.00 66.50  ? 461 ILE B CG2 1 
ATOM   5275 C CD1 . ILE B 1 461 ? 155.602 212.489 197.434 1.00 65.90  ? 461 ILE B CD1 1 
ATOM   5276 N N   . GLN B 1 462 ? 159.013 213.333 201.985 1.00 67.03  ? 462 GLN B N   1 
ATOM   5277 C CA  . GLN B 1 462 ? 159.584 213.020 203.290 1.00 67.63  ? 462 GLN B CA  1 
ATOM   5278 C C   . GLN B 1 462 ? 159.480 214.210 204.232 1.00 71.03  ? 462 GLN B C   1 
ATOM   5279 O O   . GLN B 1 462 ? 159.129 214.055 205.407 1.00 73.81  ? 462 GLN B O   1 
ATOM   5280 C CB  . GLN B 1 462 ? 161.043 212.588 203.137 1.00 62.42  ? 462 GLN B CB  1 
ATOM   5281 C CG  . GLN B 1 462 ? 161.230 211.121 202.805 1.00 64.72  ? 462 GLN B CG  1 
ATOM   5282 C CD  . GLN B 1 462 ? 162.668 210.673 202.956 1.00 70.18  ? 462 GLN B CD  1 
ATOM   5283 O OE1 . GLN B 1 462 ? 163.484 211.362 203.568 1.00 73.28  ? 462 GLN B OE1 1 
ATOM   5284 N NE2 . GLN B 1 462 ? 162.989 209.514 202.393 1.00 75.07  ? 462 GLN B NE2 1 
ATOM   5285 N N   . CYS B 1 463 ? 159.769 215.412 203.730 1.00 66.45  ? 463 CYS B N   1 
ATOM   5286 C CA  . CYS B 1 463 ? 159.665 216.595 204.574 1.00 64.45  ? 463 CYS B CA  1 
ATOM   5287 C C   . CYS B 1 463 ? 158.213 216.930 204.894 1.00 67.16  ? 463 CYS B C   1 
ATOM   5288 O O   . CYS B 1 463 ? 157.920 217.406 205.997 1.00 69.58  ? 463 CYS B O   1 
ATOM   5289 C CB  . CYS B 1 463 ? 160.363 217.776 203.905 1.00 58.43  ? 463 CYS B CB  1 
ATOM   5290 S SG  . CYS B 1 463 ? 162.101 217.918 204.372 1.00 71.21  ? 463 CYS B SG  1 
ATOM   5291 N N   . LEU B 1 464 ? 157.292 216.678 203.960 1.00 72.14  ? 464 LEU B N   1 
ATOM   5292 C CA  . LEU B 1 464 ? 155.875 216.852 204.273 1.00 68.68  ? 464 LEU B CA  1 
ATOM   5293 C C   . LEU B 1 464 ? 155.433 215.901 205.381 1.00 68.52  ? 464 LEU B C   1 
ATOM   5294 O O   . LEU B 1 464 ? 154.695 216.296 206.293 1.00 71.91  ? 464 LEU B O   1 
ATOM   5295 C CB  . LEU B 1 464 ? 155.024 216.643 203.022 1.00 66.62  ? 464 LEU B CB  1 
ATOM   5296 C CG  . LEU B 1 464 ? 155.074 217.737 201.956 1.00 63.79  ? 464 LEU B CG  1 
ATOM   5297 C CD1 . LEU B 1 464 ? 153.864 217.629 201.046 1.00 69.99  ? 464 LEU B CD1 1 
ATOM   5298 C CD2 . LEU B 1 464 ? 155.144 219.113 202.598 1.00 65.86  ? 464 LEU B CD2 1 
ATOM   5299 N N   . ARG B 1 465 ? 155.873 214.642 205.318 1.00 78.89  ? 465 ARG B N   1 
ATOM   5300 C CA  . ARG B 1 465 ? 155.543 213.686 206.371 1.00 81.22  ? 465 ARG B CA  1 
ATOM   5301 C C   . ARG B 1 465 ? 156.168 214.095 207.698 1.00 81.93  ? 465 ARG B C   1 
ATOM   5302 O O   . ARG B 1 465 ? 155.547 213.952 208.758 1.00 83.60  ? 465 ARG B O   1 
ATOM   5303 C CB  . ARG B 1 465 ? 155.999 212.284 205.968 1.00 84.59  ? 465 ARG B CB  1 
ATOM   5304 C CG  . ARG B 1 465 ? 156.013 211.279 207.109 1.00 84.98  ? 465 ARG B CG  1 
ATOM   5305 C CD  . ARG B 1 465 ? 154.617 211.052 207.669 1.00 84.76  ? 465 ARG B CD  1 
ATOM   5306 N NE  . ARG B 1 465 ? 154.631 210.162 208.824 1.00 84.65  ? 465 ARG B NE  1 
ATOM   5307 C CZ  . ARG B 1 465 ? 154.731 208.842 208.752 1.00 87.00  ? 465 ARG B CZ  1 
ATOM   5308 N NH1 . ARG B 1 465 ? 154.817 208.218 207.589 1.00 88.34  ? 465 ARG B NH1 1 
ATOM   5309 N NH2 . ARG B 1 465 ? 154.743 208.130 209.876 1.00 84.42  ? 465 ARG B NH2 1 
ATOM   5310 N N   . ARG B 1 466 ? 157.398 214.608 207.660 1.00 81.52  ? 466 ARG B N   1 
ATOM   5311 C CA  . ARG B 1 466 ? 158.035 215.083 208.883 1.00 82.00  ? 466 ARG B CA  1 
ATOM   5312 C C   . ARG B 1 466 ? 157.256 216.244 209.489 1.00 80.17  ? 466 ARG B C   1 
ATOM   5313 O O   . ARG B 1 466 ? 157.082 216.315 210.712 1.00 80.14  ? 466 ARG B O   1 
ATOM   5314 C CB  . ARG B 1 466 ? 159.480 215.486 208.597 1.00 79.49  ? 466 ARG B CB  1 
ATOM   5315 C CG  . ARG B 1 466 ? 160.479 214.936 209.597 1.00 80.68  ? 466 ARG B CG  1 
ATOM   5316 C CD  . ARG B 1 466 ? 161.801 215.684 209.536 1.00 79.55  ? 466 ARG B CD  1 
ATOM   5317 N NE  . ARG B 1 466 ? 162.710 215.277 210.602 1.00 78.44  ? 466 ARG B NE  1 
ATOM   5318 C CZ  . ARG B 1 466 ? 162.525 215.534 211.890 1.00 78.82  ? 466 ARG B CZ  1 
ATOM   5319 N NH1 . ARG B 1 466 ? 161.475 216.218 212.316 1.00 79.23  ? 466 ARG B NH1 1 
ATOM   5320 N NH2 . ARG B 1 466 ? 163.419 215.099 212.772 1.00 79.99  ? 466 ARG B NH2 1 
ATOM   5321 N N   . TYR B 1 467 ? 156.775 217.164 208.646 1.00 80.57  ? 467 TYR B N   1 
ATOM   5322 C CA  . TYR B 1 467 ? 155.931 218.248 209.139 1.00 82.04  ? 467 TYR B CA  1 
ATOM   5323 C C   . TYR B 1 467 ? 154.647 217.711 209.752 1.00 81.46  ? 467 TYR B C   1 
ATOM   5324 O O   . TYR B 1 467 ? 154.225 218.164 210.821 1.00 81.04  ? 467 TYR B O   1 
ATOM   5325 C CB  . TYR B 1 467 ? 155.597 219.223 208.013 1.00 80.13  ? 467 TYR B CB  1 
ATOM   5326 C CG  . TYR B 1 467 ? 154.465 220.163 208.362 1.00 80.47  ? 467 TYR B CG  1 
ATOM   5327 C CD1 . TYR B 1 467 ? 154.576 221.049 209.425 1.00 82.34  ? 467 TYR B CD1 1 
ATOM   5328 C CD2 . TYR B 1 467 ? 153.281 220.152 207.638 1.00 80.70  ? 467 TYR B CD2 1 
ATOM   5329 C CE1 . TYR B 1 467 ? 153.542 221.906 209.752 1.00 81.75  ? 467 TYR B CE1 1 
ATOM   5330 C CE2 . TYR B 1 467 ? 152.241 221.004 207.958 1.00 83.26  ? 467 TYR B CE2 1 
ATOM   5331 C CZ  . TYR B 1 467 ? 152.377 221.879 209.015 1.00 84.21  ? 467 TYR B CZ  1 
ATOM   5332 O OH  . TYR B 1 467 ? 151.344 222.730 209.336 1.00 84.72  ? 467 TYR B OH  1 
ATOM   5333 N N   . ARG B 1 468 ? 154.010 216.749 209.084 1.00 83.64  ? 468 ARG B N   1 
ATOM   5334 C CA  . ARG B 1 468 ? 152.803 216.142 209.635 1.00 83.19  ? 468 ARG B CA  1 
ATOM   5335 C C   . ARG B 1 468 ? 153.083 215.514 210.994 1.00 84.08  ? 468 ARG B C   1 
ATOM   5336 O O   . ARG B 1 468 ? 152.234 215.546 211.893 1.00 87.84  ? 468 ARG B O   1 
ATOM   5337 C CB  . ARG B 1 468 ? 152.252 215.104 208.657 1.00 82.31  ? 468 ARG B CB  1 
ATOM   5338 C CG  . ARG B 1 468 ? 151.172 214.202 209.226 1.00 80.82  ? 468 ARG B CG  1 
ATOM   5339 C CD  . ARG B 1 468 ? 151.164 212.859 208.516 1.00 84.31  ? 468 ARG B CD  1 
ATOM   5340 N NE  . ARG B 1 468 ? 151.070 213.013 207.069 1.00 84.04  ? 468 ARG B NE  1 
ATOM   5341 C CZ  . ARG B 1 468 ? 151.073 212.006 206.206 1.00 82.46  ? 468 ARG B CZ  1 
ATOM   5342 N NH1 . ARG B 1 468 ? 151.163 210.749 206.610 1.00 81.58  ? 468 ARG B NH1 1 
ATOM   5343 N NH2 . ARG B 1 468 ? 150.985 212.267 204.905 1.00 81.19  ? 468 ARG B NH2 1 
ATOM   5344 N N   . ASP B 1 469 ? 154.278 214.949 211.163 1.00 92.08  ? 469 ASP B N   1 
ATOM   5345 C CA  . ASP B 1 469 ? 154.656 214.371 212.449 1.00 94.50  ? 469 ASP B CA  1 
ATOM   5346 C C   . ASP B 1 469 ? 154.844 215.449 213.511 1.00 95.27  ? 469 ASP B C   1 
ATOM   5347 O O   . ASP B 1 469 ? 154.402 215.289 214.654 1.00 94.50  ? 469 ASP B O   1 
ATOM   5348 C CB  . ASP B 1 469 ? 155.929 213.538 212.294 1.00 94.21  ? 469 ASP B CB  1 
ATOM   5349 C CG  . ASP B 1 469 ? 155.720 212.309 211.432 1.00 96.65  ? 469 ASP B CG  1 
ATOM   5350 O OD1 . ASP B 1 469 ? 154.562 212.037 211.053 1.00 98.02  ? 469 ASP B OD1 1 
ATOM   5351 O OD2 . ASP B 1 469 ? 156.715 211.615 211.132 1.00 94.73  ? 469 ASP B OD2 1 
ATOM   5352 N N   . THR B 1 470 ? 155.501 216.557 213.157 1.00 94.40  ? 470 THR B N   1 
ATOM   5353 C CA  . THR B 1 470 ? 155.840 217.574 214.148 1.00 94.21  ? 470 THR B CA  1 
ATOM   5354 C C   . THR B 1 470 ? 154.894 218.768 214.161 1.00 91.06  ? 470 THR B C   1 
ATOM   5355 O O   . THR B 1 470 ? 154.834 219.470 215.177 1.00 91.01  ? 470 THR B O   1 
ATOM   5356 C CB  . THR B 1 470 ? 157.270 218.086 213.930 1.00 93.07  ? 470 THR B CB  1 
ATOM   5357 O OG1 . THR B 1 470 ? 157.620 218.986 214.989 1.00 91.43  ? 470 THR B OG1 1 
ATOM   5358 C CG2 . THR B 1 470 ? 157.377 218.827 212.610 1.00 90.67  ? 470 THR B CG2 1 
ATOM   5359 N N   . LYS B 1 471 ? 154.161 219.016 213.072 1.00 89.01  ? 471 LYS B N   1 
ATOM   5360 C CA  . LYS B 1 471 ? 153.267 220.171 212.959 1.00 89.26  ? 471 LYS B CA  1 
ATOM   5361 C C   . LYS B 1 471 ? 154.014 221.479 213.222 1.00 91.96  ? 471 LYS B C   1 
ATOM   5362 O O   . LYS B 1 471 ? 153.514 222.388 213.888 1.00 94.44  ? 471 LYS B O   1 
ATOM   5363 C CB  . LYS B 1 471 ? 152.058 220.026 213.887 1.00 90.17  ? 471 LYS B CB  1 
ATOM   5364 C CG  . LYS B 1 471 ? 151.287 218.734 213.684 1.00 90.58  ? 471 LYS B CG  1 
ATOM   5365 C CD  . LYS B 1 471 ? 149.787 218.972 213.720 1.00 91.39  ? 471 LYS B CD  1 
ATOM   5366 C CE  . LYS B 1 471 ? 149.025 217.693 213.418 1.00 91.05  ? 471 LYS B CE  1 
ATOM   5367 N NZ  . LYS B 1 471 ? 149.396 216.595 214.352 1.00 88.97  ? 471 LYS B NZ  1 
ATOM   5368 N N   . ARG B 1 472 ? 155.230 221.566 212.688 1.00 89.68  ? 472 ARG B N   1 
ATOM   5369 C CA  . ARG B 1 472 ? 156.066 222.755 212.809 1.00 89.33  ? 472 ARG B CA  1 
ATOM   5370 C C   . ARG B 1 472 ? 156.535 223.151 211.418 1.00 87.95  ? 472 ARG B C   1 
ATOM   5371 O O   . ARG B 1 472 ? 157.200 222.363 210.737 1.00 88.85  ? 472 ARG B O   1 
ATOM   5372 C CB  . ARG B 1 472 ? 157.249 222.492 213.747 1.00 86.11  ? 472 ARG B CB  1 
ATOM   5373 C CG  . ARG B 1 472 ? 158.266 223.614 213.840 1.00 87.84  ? 472 ARG B CG  1 
ATOM   5374 C CD  . ARG B 1 472 ? 159.600 223.086 214.351 1.00 88.64  ? 472 ARG B CD  1 
ATOM   5375 N NE  . ARG B 1 472 ? 160.661 224.080 214.247 1.00 89.32  ? 472 ARG B NE  1 
ATOM   5376 C CZ  . ARG B 1 472 ? 161.603 224.271 215.160 1.00 87.97  ? 472 ARG B CZ  1 
ATOM   5377 N NH1 . ARG B 1 472 ? 161.649 223.548 216.267 1.00 85.61  ? 472 ARG B NH1 1 
ATOM   5378 N NH2 . ARG B 1 472 ? 162.522 225.211 214.958 1.00 88.37  ? 472 ARG B NH2 1 
ATOM   5379 N N   . ALA B 1 473 ? 156.188 224.371 210.997 1.00 81.27  ? 473 ALA B N   1 
ATOM   5380 C CA  . ALA B 1 473 ? 156.433 224.778 209.616 1.00 76.52  ? 473 ALA B CA  1 
ATOM   5381 C C   . ALA B 1 473 ? 157.914 225.017 209.352 1.00 81.18  ? 473 ALA B C   1 
ATOM   5382 O O   . ALA B 1 473 ? 158.440 224.593 208.318 1.00 85.18  ? 473 ALA B O   1 
ATOM   5383 C CB  . ALA B 1 473 ? 155.620 226.029 209.287 1.00 76.97  ? 473 ALA B CB  1 
ATOM   5384 N N   . PHE B 1 474 ? 158.599 225.700 210.264 1.00 87.96  ? 474 PHE B N   1 
ATOM   5385 C CA  . PHE B 1 474 ? 160.023 225.967 210.111 1.00 87.32  ? 474 PHE B CA  1 
ATOM   5386 C C   . PHE B 1 474 ? 160.809 224.772 210.632 1.00 88.19  ? 474 PHE B C   1 
ATOM   5387 O O   . PHE B 1 474 ? 160.702 224.452 211.821 1.00 89.26  ? 474 PHE B O   1 
ATOM   5388 C CB  . PHE B 1 474 ? 160.405 227.230 210.871 1.00 88.57  ? 474 PHE B CB  1 
ATOM   5389 C CG  . PHE B 1 474 ? 161.645 227.917 210.356 1.00 90.17  ? 474 PHE B CG  1 
ATOM   5390 C CD1 . PHE B 1 474 ? 162.793 227.201 210.062 1.00 86.79  ? 474 PHE B CD1 1 
ATOM   5391 C CD2 . PHE B 1 474 ? 161.655 229.288 210.162 1.00 91.60  ? 474 PHE B CD2 1 
ATOM   5392 C CE1 . PHE B 1 474 ? 163.925 227.836 209.590 1.00 86.97  ? 474 PHE B CE1 1 
ATOM   5393 C CE2 . PHE B 1 474 ? 162.784 229.930 209.690 1.00 91.57  ? 474 PHE B CE2 1 
ATOM   5394 C CZ  . PHE B 1 474 ? 163.921 229.202 209.403 1.00 92.22  ? 474 PHE B CZ  1 
ATOM   5395 N N   . PRO B 1 475 ? 161.617 224.097 209.801 1.00 77.63  ? 475 PRO B N   1 
ATOM   5396 C CA  . PRO B 1 475 ? 161.909 224.357 208.391 1.00 76.29  ? 475 PRO B CA  1 
ATOM   5397 C C   . PRO B 1 475 ? 161.280 223.356 207.430 1.00 77.25  ? 475 PRO B C   1 
ATOM   5398 O O   . PRO B 1 475 ? 161.768 223.188 206.321 1.00 81.12  ? 475 PRO B O   1 
ATOM   5399 C CB  . PRO B 1 475 ? 163.432 224.242 208.365 1.00 78.71  ? 475 PRO B CB  1 
ATOM   5400 C CG  . PRO B 1 475 ? 163.689 223.076 209.316 1.00 75.38  ? 475 PRO B CG  1 
ATOM   5401 C CD  . PRO B 1 475 ? 162.559 223.102 210.341 1.00 72.35  ? 475 PRO B CD  1 
ATOM   5402 N N   . HIS B 1 476 ? 160.202 222.673 207.813 1.00 73.56  ? 476 HIS B N   1 
ATOM   5403 C CA  . HIS B 1 476 ? 159.688 221.585 206.986 1.00 75.85  ? 476 HIS B CA  1 
ATOM   5404 C C   . HIS B 1 476 ? 159.018 222.111 205.720 1.00 75.94  ? 476 HIS B C   1 
ATOM   5405 O O   . HIS B 1 476 ? 159.283 221.621 204.614 1.00 79.47  ? 476 HIS B O   1 
ATOM   5406 C CB  . HIS B 1 476 ? 158.726 220.732 207.809 1.00 71.27  ? 476 HIS B CB  1 
ATOM   5407 C CG  . HIS B 1 476 ? 159.371 220.069 208.986 1.00 67.15  ? 476 HIS B CG  1 
ATOM   5408 N ND1 . HIS B 1 476 ? 159.229 218.725 209.254 1.00 72.36  ? 476 HIS B ND1 1 
ATOM   5409 C CD2 . HIS B 1 476 ? 160.162 220.566 209.966 1.00 67.39  ? 476 HIS B CD2 1 
ATOM   5410 C CE1 . HIS B 1 476 ? 159.904 218.423 210.348 1.00 76.77  ? 476 HIS B CE1 1 
ATOM   5411 N NE2 . HIS B 1 476 ? 160.480 219.522 210.800 1.00 75.00  ? 476 HIS B NE2 1 
ATOM   5412 N N   . LEU B 1 477 ? 158.157 223.121 205.856 1.00 71.25  ? 477 LEU B N   1 
ATOM   5413 C CA  . LEU B 1 477 ? 157.562 223.735 204.674 1.00 71.99  ? 477 LEU B CA  1 
ATOM   5414 C C   . LEU B 1 477 ? 158.601 224.497 203.867 1.00 73.82  ? 477 LEU B C   1 
ATOM   5415 O O   . LEU B 1 477 ? 158.487 224.591 202.640 1.00 80.03  ? 477 LEU B O   1 
ATOM   5416 C CB  . LEU B 1 477 ? 156.411 224.666 205.065 1.00 79.52  ? 477 LEU B CB  1 
ATOM   5417 C CG  . LEU B 1 477 ? 155.037 224.079 205.412 1.00 83.24  ? 477 LEU B CG  1 
ATOM   5418 C CD1 . LEU B 1 477 ? 154.405 223.449 204.178 1.00 78.09  ? 477 LEU B CD1 1 
ATOM   5419 C CD2 . LEU B 1 477 ? 155.091 223.083 206.561 1.00 81.12  ? 477 LEU B CD2 1 
ATOM   5420 N N   . VAL B 1 478 ? 159.626 225.029 204.533 1.00 72.12  ? 478 VAL B N   1 
ATOM   5421 C CA  . VAL B 1 478 ? 160.729 225.671 203.825 1.00 76.85  ? 478 VAL B CA  1 
ATOM   5422 C C   . VAL B 1 478 ? 161.441 224.657 202.934 1.00 78.64  ? 478 VAL B C   1 
ATOM   5423 O O   . VAL B 1 478 ? 161.768 224.939 201.775 1.00 73.78  ? 478 VAL B O   1 
ATOM   5424 C CB  . VAL B 1 478 ? 161.689 226.328 204.834 1.00 75.06  ? 478 VAL B CB  1 
ATOM   5425 C CG1 . VAL B 1 478 ? 162.552 227.378 204.163 1.00 69.55  ? 478 VAL B CG1 1 
ATOM   5426 C CG2 . VAL B 1 478 ? 160.902 226.944 205.980 1.00 72.57  ? 478 VAL B CG2 1 
ATOM   5427 N N   . ASN B 1 479 ? 161.680 223.454 203.463 1.00 77.90  ? 479 ASN B N   1 
ATOM   5428 C CA  . ASN B 1 479 ? 162.301 222.390 202.677 1.00 73.04  ? 479 ASN B CA  1 
ATOM   5429 C C   . ASN B 1 479 ? 161.396 221.942 201.538 1.00 76.38  ? 479 ASN B C   1 
ATOM   5430 O O   . ASN B 1 479 ? 161.865 221.672 200.425 1.00 83.40  ? 479 ASN B O   1 
ATOM   5431 C CB  . ASN B 1 479 ? 162.645 221.210 203.582 1.00 64.17  ? 479 ASN B CB  1 
ATOM   5432 C CG  . ASN B 1 479 ? 164.107 220.825 203.509 1.00 70.96  ? 479 ASN B CG  1 
ATOM   5433 O OD1 . ASN B 1 479 ? 164.899 221.480 202.835 1.00 74.11  ? 479 ASN B OD1 1 
ATOM   5434 N ND2 . ASN B 1 479 ? 164.474 219.760 204.210 1.00 75.17  ? 479 ASN B ND2 1 
ATOM   5435 N N   . ALA B 1 480 ? 160.095 221.823 201.810 1.00 64.66  ? 480 ALA B N   1 
ATOM   5436 C CA  . ALA B 1 480 ? 159.153 221.471 200.754 1.00 63.11  ? 480 ALA B CA  1 
ATOM   5437 C C   . ALA B 1 480 ? 159.207 222.488 199.623 1.00 58.90  ? 480 ALA B C   1 
ATOM   5438 O O   . ALA B 1 480 ? 159.245 222.121 198.442 1.00 54.66  ? 480 ALA B O   1 
ATOM   5439 C CB  . ALA B 1 480 ? 157.739 221.371 201.325 1.00 64.72  ? 480 ALA B CB  1 
ATOM   5440 N N   . GLY B 1 481 ? 159.237 223.775 199.972 1.00 64.59  ? 481 GLY B N   1 
ATOM   5441 C CA  . GLY B 1 481 ? 159.400 224.804 198.962 1.00 65.17  ? 481 GLY B CA  1 
ATOM   5442 C C   . GLY B 1 481 ? 160.708 224.675 198.207 1.00 65.61  ? 481 GLY B C   1 
ATOM   5443 O O   . GLY B 1 481 ? 160.738 224.795 196.980 1.00 74.90  ? 481 GLY B O   1 
ATOM   5444 N N   . LYS B 1 482 ? 161.802 224.412 198.928 1.00 62.13  ? 482 LYS B N   1 
ATOM   5445 C CA  . LYS B 1 482 ? 163.112 224.299 198.292 1.00 69.93  ? 482 LYS B CA  1 
ATOM   5446 C C   . LYS B 1 482 ? 163.135 223.180 197.260 1.00 70.35  ? 482 LYS B C   1 
ATOM   5447 O O   . LYS B 1 482 ? 163.669 223.351 196.158 1.00 69.11  ? 482 LYS B O   1 
ATOM   5448 C CB  . LYS B 1 482 ? 164.191 224.068 199.350 1.00 69.82  ? 482 LYS B CB  1 
ATOM   5449 C CG  . LYS B 1 482 ? 165.547 223.683 198.780 1.00 65.96  ? 482 LYS B CG  1 
ATOM   5450 C CD  . LYS B 1 482 ? 166.667 223.962 199.767 1.00 74.28  ? 482 LYS B CD  1 
ATOM   5451 C CE  . LYS B 1 482 ? 166.891 222.782 200.700 1.00 70.51  ? 482 LYS B CE  1 
ATOM   5452 N NZ  . LYS B 1 482 ? 167.510 221.620 200.004 1.00 65.09  ? 482 LYS B NZ  1 
ATOM   5453 N N   . TYR B 1 483 ? 162.559 222.028 197.597 1.00 62.96  ? 483 TYR B N   1 
ATOM   5454 C CA  . TYR B 1 483 ? 162.526 220.930 196.638 1.00 58.14  ? 483 TYR B CA  1 
ATOM   5455 C C   . TYR B 1 483 ? 161.531 221.187 195.510 1.00 70.29  ? 483 TYR B C   1 
ATOM   5456 O O   . TYR B 1 483 ? 161.756 220.742 194.376 1.00 78.53  ? 483 TYR B O   1 
ATOM   5457 C CB  . TYR B 1 483 ? 162.220 219.613 197.354 1.00 52.34  ? 483 TYR B CB  1 
ATOM   5458 C CG  . TYR B 1 483 ? 163.320 219.191 198.303 1.00 55.97  ? 483 TYR B CG  1 
ATOM   5459 C CD1 . TYR B 1 483 ? 164.605 218.945 197.838 1.00 62.76  ? 483 TYR B CD1 1 
ATOM   5460 C CD2 . TYR B 1 483 ? 163.078 219.040 199.661 1.00 59.29  ? 483 TYR B CD2 1 
ATOM   5461 C CE1 . TYR B 1 483 ? 165.616 218.564 198.697 1.00 60.05  ? 483 TYR B CE1 1 
ATOM   5462 C CE2 . TYR B 1 483 ? 164.084 218.662 200.530 1.00 57.40  ? 483 TYR B CE2 1 
ATOM   5463 C CZ  . TYR B 1 483 ? 165.351 218.424 200.042 1.00 55.55  ? 483 TYR B CZ  1 
ATOM   5464 O OH  . TYR B 1 483 ? 166.356 218.042 200.900 1.00 65.02  ? 483 TYR B OH  1 
ATOM   5465 N N   . SER B 1 484 ? 160.446 221.917 195.782 1.00 67.87  ? 484 SER B N   1 
ATOM   5466 C CA  . SER B 1 484 ? 159.537 222.276 194.699 1.00 62.99  ? 484 SER B CA  1 
ATOM   5467 C C   . SER B 1 484 ? 160.193 223.239 193.718 1.00 61.77  ? 484 SER B C   1 
ATOM   5468 O O   . SER B 1 484 ? 159.810 223.276 192.543 1.00 68.07  ? 484 SER B O   1 
ATOM   5469 C CB  . SER B 1 484 ? 158.249 222.880 195.257 1.00 74.50  ? 484 SER B CB  1 
ATOM   5470 O OG  . SER B 1 484 ? 158.526 223.940 196.149 1.00 78.77  ? 484 SER B OG  1 
ATOM   5471 N N   . THR B 1 485 ? 161.173 224.027 194.173 1.00 59.87  ? 485 THR B N   1 
ATOM   5472 C CA  . THR B 1 485 ? 161.911 224.873 193.235 1.00 62.91  ? 485 THR B CA  1 
ATOM   5473 C C   . THR B 1 485 ? 162.584 224.039 192.153 1.00 65.31  ? 485 THR B C   1 
ATOM   5474 O O   . THR B 1 485 ? 162.485 224.355 190.965 1.00 76.00  ? 485 THR B O   1 
ATOM   5475 C CB  . THR B 1 485 ? 162.954 225.739 193.947 1.00 61.02  ? 485 THR B CB  1 
ATOM   5476 O OG1 . THR B 1 485 ? 164.127 224.964 194.228 1.00 63.95  ? 485 THR B OG1 1 
ATOM   5477 C CG2 . THR B 1 485 ? 162.410 226.380 195.196 1.00 66.08  ? 485 THR B CG2 1 
ATOM   5478 N N   . THR B 1 486 ? 163.270 222.960 192.539 1.00 62.32  ? 486 THR B N   1 
ATOM   5479 C CA  . THR B 1 486 ? 163.914 222.122 191.530 1.00 67.92  ? 486 THR B CA  1 
ATOM   5480 C C   . THR B 1 486 ? 162.900 221.252 190.791 1.00 70.64  ? 486 THR B C   1 
ATOM   5481 O O   . THR B 1 486 ? 163.127 220.883 189.631 1.00 76.08  ? 486 THR B O   1 
ATOM   5482 C CB  . THR B 1 486 ? 165.019 221.273 192.165 1.00 73.14  ? 486 THR B CB  1 
ATOM   5483 O OG1 . THR B 1 486 ? 165.999 220.941 191.172 1.00 75.33  ? 486 THR B OG1 1 
ATOM   5484 C CG2 . THR B 1 486 ? 164.464 220.002 192.761 1.00 69.37  ? 486 THR B CG2 1 
ATOM   5485 N N   . PHE B 1 487 ? 161.770 220.935 191.429 1.00 64.30  ? 487 PHE B N   1 
ATOM   5486 C CA  . PHE B 1 487 ? 160.674 220.294 190.706 1.00 68.05  ? 487 PHE B CA  1 
ATOM   5487 C C   . PHE B 1 487 ? 160.234 221.148 189.522 1.00 69.66  ? 487 PHE B C   1 
ATOM   5488 O O   . PHE B 1 487 ? 160.161 220.672 188.380 1.00 67.49  ? 487 PHE B O   1 
ATOM   5489 C CB  . PHE B 1 487 ? 159.502 220.044 191.655 1.00 61.80  ? 487 PHE B CB  1 
ATOM   5490 C CG  . PHE B 1 487 ? 158.744 218.781 191.370 1.00 68.64  ? 487 PHE B CG  1 
ATOM   5491 C CD1 . PHE B 1 487 ? 158.362 218.463 190.078 1.00 70.02  ? 487 PHE B CD1 1 
ATOM   5492 C CD2 . PHE B 1 487 ? 158.405 217.915 192.396 1.00 67.20  ? 487 PHE B CD2 1 
ATOM   5493 C CE1 . PHE B 1 487 ? 157.660 217.304 189.812 1.00 68.03  ? 487 PHE B CE1 1 
ATOM   5494 C CE2 . PHE B 1 487 ? 157.703 216.753 192.137 1.00 70.25  ? 487 PHE B CE2 1 
ATOM   5495 C CZ  . PHE B 1 487 ? 157.330 216.448 190.842 1.00 70.48  ? 487 PHE B CZ  1 
ATOM   5496 N N   . PHE B 1 488 ? 159.948 222.424 189.781 1.00 72.71  ? 488 PHE B N   1 
ATOM   5497 C CA  . PHE B 1 488 ? 159.557 223.342 188.721 1.00 71.76  ? 488 PHE B CA  1 
ATOM   5498 C C   . PHE B 1 488 ? 160.707 223.629 187.766 1.00 67.83  ? 488 PHE B C   1 
ATOM   5499 O O   . PHE B 1 488 ? 160.471 223.830 186.575 1.00 72.37  ? 488 PHE B O   1 
ATOM   5500 C CB  . PHE B 1 488 ? 159.019 224.638 189.326 1.00 71.80  ? 488 PHE B CB  1 
ATOM   5501 C CG  . PHE B 1 488 ? 157.725 224.464 190.071 1.00 71.74  ? 488 PHE B CG  1 
ATOM   5502 C CD1 . PHE B 1 488 ? 156.747 223.607 189.593 1.00 70.94  ? 488 PHE B CD1 1 
ATOM   5503 C CD2 . PHE B 1 488 ? 157.488 225.154 191.247 1.00 72.07  ? 488 PHE B CD2 1 
ATOM   5504 C CE1 . PHE B 1 488 ? 155.557 223.441 190.274 1.00 71.58  ? 488 PHE B CE1 1 
ATOM   5505 C CE2 . PHE B 1 488 ? 156.300 224.992 191.934 1.00 74.30  ? 488 PHE B CE2 1 
ATOM   5506 C CZ  . PHE B 1 488 ? 155.333 224.135 191.447 1.00 74.87  ? 488 PHE B CZ  1 
ATOM   5507 N N   . MET B 1 489 ? 161.944 223.663 188.268 1.00 67.11  ? 489 MET B N   1 
ATOM   5508 C CA  . MET B 1 489 ? 163.119 223.632 187.400 1.00 71.54  ? 489 MET B CA  1 
ATOM   5509 C C   . MET B 1 489 ? 162.997 222.570 186.322 1.00 76.55  ? 489 MET B C   1 
ATOM   5510 O O   . MET B 1 489 ? 163.040 222.875 185.126 1.00 77.89  ? 489 MET B O   1 
ATOM   5511 C CB  . MET B 1 489 ? 164.376 223.384 188.230 1.00 74.94  ? 489 MET B CB  1 
ATOM   5512 C CG  . MET B 1 489 ? 165.668 223.686 187.507 1.00 76.83  ? 489 MET B CG  1 
ATOM   5513 S SD  . MET B 1 489 ? 166.030 225.393 187.118 1.00 76.21  ? 489 MET B SD  1 
ATOM   5514 C CE  . MET B 1 489 ? 167.664 225.162 186.423 1.00 72.87  ? 489 MET B CE  1 
ATOM   5515 N N   . VAL B 1 490 ? 162.876 221.309 186.731 1.00 80.89  ? 490 VAL B N   1 
ATOM   5516 C CA  . VAL B 1 490 ? 162.886 220.221 185.759 1.00 77.92  ? 490 VAL B CA  1 
ATOM   5517 C C   . VAL B 1 490 ? 161.663 220.300 184.852 1.00 83.44  ? 490 VAL B C   1 
ATOM   5518 O O   . VAL B 1 490 ? 161.765 220.121 183.628 1.00 87.15  ? 490 VAL B O   1 
ATOM   5519 C CB  . VAL B 1 490 ? 162.977 218.867 186.482 1.00 77.73  ? 490 VAL B CB  1 
ATOM   5520 C CG1 . VAL B 1 490 ? 163.018 217.741 185.476 1.00 77.98  ? 490 VAL B CG1 1 
ATOM   5521 C CG2 . VAL B 1 490 ? 164.200 218.833 187.382 1.00 78.62  ? 490 VAL B CG2 1 
ATOM   5522 N N   . THR B 1 491 ? 160.490 220.576 185.433 1.00 85.75  ? 491 THR B N   1 
ATOM   5523 C CA  . THR B 1 491 ? 159.270 220.656 184.634 1.00 86.24  ? 491 THR B CA  1 
ATOM   5524 C C   . THR B 1 491 ? 159.372 221.746 183.571 1.00 86.51  ? 491 THR B C   1 
ATOM   5525 O O   . THR B 1 491 ? 159.119 221.494 182.385 1.00 88.78  ? 491 THR B O   1 
ATOM   5526 C CB  . THR B 1 491 ? 158.067 220.900 185.546 1.00 86.01  ? 491 THR B CB  1 
ATOM   5527 O OG1 . THR B 1 491 ? 157.850 219.746 186.368 1.00 86.21  ? 491 THR B OG1 1 
ATOM   5528 C CG2 . THR B 1 491 ? 156.816 221.177 184.726 1.00 88.03  ? 491 THR B CG2 1 
ATOM   5529 N N   . PHE B 1 492 ? 159.765 222.956 183.974 1.00 84.26  ? 492 PHE B N   1 
ATOM   5530 C CA  . PHE B 1 492 ? 159.959 224.072 183.062 1.00 83.61  ? 492 PHE B CA  1 
ATOM   5531 C C   . PHE B 1 492 ? 161.024 223.797 182.016 1.00 85.92  ? 492 PHE B C   1 
ATOM   5532 O O   . PHE B 1 492 ? 160.825 224.147 180.848 1.00 90.68  ? 492 PHE B O   1 
ATOM   5533 C CB  . PHE B 1 492 ? 160.354 225.323 183.848 1.00 84.66  ? 492 PHE B CB  1 
ATOM   5534 C CG  . PHE B 1 492 ? 159.207 226.235 184.162 1.00 86.07  ? 492 PHE B CG  1 
ATOM   5535 C CD1 . PHE B 1 492 ? 158.463 226.809 183.148 1.00 87.24  ? 492 PHE B CD1 1 
ATOM   5536 C CD2 . PHE B 1 492 ? 158.884 226.532 185.475 1.00 86.59  ? 492 PHE B CD2 1 
ATOM   5537 C CE1 . PHE B 1 492 ? 157.412 227.653 183.440 1.00 87.01  ? 492 PHE B CE1 1 
ATOM   5538 C CE2 . PHE B 1 492 ? 157.834 227.374 185.770 1.00 84.49  ? 492 PHE B CE2 1 
ATOM   5539 C CZ  . PHE B 1 492 ? 157.097 227.936 184.751 1.00 86.89  ? 492 PHE B CZ  1 
ATOM   5540 N N   . ALA B 1 493 ? 162.150 223.197 182.409 1.00 87.17  ? 493 ALA B N   1 
ATOM   5541 C CA  . ALA B 1 493 ? 163.213 222.910 181.457 1.00 88.38  ? 493 ALA B CA  1 
ATOM   5542 C C   . ALA B 1 493 ? 162.734 221.957 180.373 1.00 88.13  ? 493 ALA B C   1 
ATOM   5543 O O   . ALA B 1 493 ? 162.905 222.238 179.179 1.00 89.21  ? 493 ALA B O   1 
ATOM   5544 C CB  . ALA B 1 493 ? 164.427 222.329 182.181 1.00 91.86  ? 493 ALA B CB  1 
ATOM   5545 N N   . ALA B 1 494 ? 162.101 220.846 180.766 1.00 90.38  ? 494 ALA B N   1 
ATOM   5546 C CA  . ALA B 1 494 ? 161.565 219.925 179.774 1.00 91.83  ? 494 ALA B CA  1 
ATOM   5547 C C   . ALA B 1 494 ? 160.513 220.593 178.899 1.00 96.65  ? 494 ALA B C   1 
ATOM   5548 O O   . ALA B 1 494 ? 160.528 220.421 177.671 1.00 100.69 ? 494 ALA B O   1 
ATOM   5549 C CB  . ALA B 1 494 ? 160.975 218.696 180.464 1.00 91.64  ? 494 ALA B CB  1 
ATOM   5550 N N   . LEU B 1 495 ? 159.620 221.379 179.504 1.00 105.84 ? 495 LEU B N   1 
ATOM   5551 C CA  . LEU B 1 495 ? 158.548 222.004 178.742 1.00 106.96 ? 495 LEU B CA  1 
ATOM   5552 C C   . LEU B 1 495 ? 159.100 222.973 177.702 1.00 104.64 ? 495 LEU B C   1 
ATOM   5553 O O   . LEU B 1 495 ? 158.708 222.925 176.530 1.00 105.57 ? 495 LEU B O   1 
ATOM   5554 C CB  . LEU B 1 495 ? 157.570 222.704 179.690 1.00 107.30 ? 495 LEU B CB  1 
ATOM   5555 C CG  . LEU B 1 495 ? 156.460 223.562 179.079 1.00 107.49 ? 495 LEU B CG  1 
ATOM   5556 C CD1 . LEU B 1 495 ? 155.204 223.461 179.925 1.00 107.33 ? 495 LEU B CD1 1 
ATOM   5557 C CD2 . LEU B 1 495 ? 156.889 225.014 178.962 1.00 105.12 ? 495 LEU B CD2 1 
ATOM   5558 N N   . TYR B 1 496 ? 160.024 223.859 178.094 1.00 108.09 ? 496 TYR B N   1 
ATOM   5559 C CA  . TYR B 1 496 ? 160.438 224.847 177.105 1.00 108.39 ? 496 TYR B CA  1 
ATOM   5560 C C   . TYR B 1 496 ? 161.454 224.259 176.141 1.00 108.07 ? 496 TYR B C   1 
ATOM   5561 O O   . TYR B 1 496 ? 161.623 224.796 175.045 1.00 111.03 ? 496 TYR B O   1 
ATOM   5562 C CB  . TYR B 1 496 ? 161.030 226.119 177.724 1.00 109.26 ? 496 TYR B CB  1 
ATOM   5563 C CG  . TYR B 1 496 ? 162.505 226.091 178.064 1.00 113.50 ? 496 TYR B CG  1 
ATOM   5564 C CD1 . TYR B 1 496 ? 163.010 225.320 179.091 1.00 116.39 ? 496 TYR B CD1 1 
ATOM   5565 C CD2 . TYR B 1 496 ? 163.395 226.883 177.350 1.00 110.97 ? 496 TYR B CD2 1 
ATOM   5566 C CE1 . TYR B 1 496 ? 164.369 225.323 179.383 1.00 114.56 ? 496 TYR B CE1 1 
ATOM   5567 C CE2 . TYR B 1 496 ? 164.741 226.893 177.635 1.00 111.91 ? 496 TYR B CE2 1 
ATOM   5568 C CZ  . TYR B 1 496 ? 165.226 226.114 178.652 1.00 115.41 ? 496 TYR B CZ  1 
ATOM   5569 O OH  . TYR B 1 496 ? 166.572 226.128 178.935 1.00 113.72 ? 496 TYR B OH  1 
ATOM   5570 N N   . SER B 1 497 ? 162.123 223.162 176.507 1.00 108.61 ? 497 SER B N   1 
ATOM   5571 C CA  . SER B 1 497 ? 162.919 222.443 175.521 1.00 111.53 ? 497 SER B CA  1 
ATOM   5572 C C   . SER B 1 497 ? 162.028 221.864 174.431 1.00 113.89 ? 497 SER B C   1 
ATOM   5573 O O   . SER B 1 497 ? 162.332 221.979 173.237 1.00 115.96 ? 497 SER B O   1 
ATOM   5574 C CB  . SER B 1 497 ? 163.725 221.339 176.199 1.00 114.25 ? 497 SER B CB  1 
ATOM   5575 O OG  . SER B 1 497 ? 164.314 220.484 175.237 1.00 112.47 ? 497 SER B OG  1 
ATOM   5576 N N   . THR B 1 498 ? 160.908 221.251 174.826 1.00 118.47 ? 498 THR B N   1 
ATOM   5577 C CA  . THR B 1 498 ? 159.940 220.792 173.834 1.00 121.56 ? 498 THR B CA  1 
ATOM   5578 C C   . THR B 1 498 ? 159.390 221.964 173.027 1.00 121.77 ? 498 THR B C   1 
ATOM   5579 O O   . THR B 1 498 ? 159.170 221.849 171.815 1.00 119.94 ? 498 THR B O   1 
ATOM   5580 C CB  . THR B 1 498 ? 158.807 220.025 174.519 1.00 120.90 ? 498 THR B CB  1 
ATOM   5581 O OG1 . THR B 1 498 ? 159.342 218.875 175.186 1.00 120.78 ? 498 THR B OG1 1 
ATOM   5582 C CG2 . THR B 1 498 ? 157.770 219.572 173.501 1.00 121.48 ? 498 THR B CG2 1 
ATOM   5583 N N   . HIS B 1 499 ? 159.173 223.104 173.687 1.00 126.80 ? 499 HIS B N   1 
ATOM   5584 C CA  . HIS B 1 499 ? 158.675 224.295 173.004 1.00 125.42 ? 499 HIS B CA  1 
ATOM   5585 C C   . HIS B 1 499 ? 159.663 224.778 171.946 1.00 125.14 ? 499 HIS B C   1 
ATOM   5586 O O   . HIS B 1 499 ? 159.271 225.149 170.833 1.00 125.24 ? 499 HIS B O   1 
ATOM   5587 C CB  . HIS B 1 499 ? 158.408 225.394 174.034 1.00 127.10 ? 499 HIS B CB  1 
ATOM   5588 C CG  . HIS B 1 499 ? 157.157 226.175 173.782 1.00 124.29 ? 499 HIS B CG  1 
ATOM   5589 N ND1 . HIS B 1 499 ? 155.899 225.639 173.951 1.00 124.37 ? 499 HIS B ND1 1 
ATOM   5590 C CD2 . HIS B 1 499 ? 156.970 227.459 173.396 1.00 124.12 ? 499 HIS B CD2 1 
ATOM   5591 C CE1 . HIS B 1 499 ? 154.990 226.555 173.668 1.00 126.64 ? 499 HIS B CE1 1 
ATOM   5592 N NE2 . HIS B 1 499 ? 155.614 227.669 173.330 1.00 126.97 ? 499 HIS B NE2 1 
ATOM   5593 N N   . LYS B 1 500 ? 160.953 224.789 172.287 1.00 126.31 ? 500 LYS B N   1 
ATOM   5594 C CA  . LYS B 1 500 ? 161.987 225.195 171.340 1.00 126.16 ? 500 LYS B CA  1 
ATOM   5595 C C   . LYS B 1 500 ? 162.109 224.197 170.196 1.00 127.71 ? 500 LYS B C   1 
ATOM   5596 O O   . LYS B 1 500 ? 162.354 224.589 169.048 1.00 128.89 ? 500 LYS B O   1 
ATOM   5597 C CB  . LYS B 1 500 ? 163.325 225.350 172.064 1.00 125.40 ? 500 LYS B CB  1 
ATOM   5598 C CG  . LYS B 1 500 ? 164.506 225.653 171.155 1.00 124.83 ? 500 LYS B CG  1 
ATOM   5599 C CD  . LYS B 1 500 ? 164.277 226.914 170.339 1.00 125.91 ? 500 LYS B CD  1 
ATOM   5600 C CE  . LYS B 1 500 ? 165.511 227.277 169.529 1.00 125.39 ? 500 LYS B CE  1 
ATOM   5601 N NZ  . LYS B 1 500 ? 165.218 228.311 168.499 1.00 124.52 ? 500 LYS B NZ  1 
ATOM   5602 N N   . GLU B 1 501 ? 161.946 222.904 170.488 1.00 132.26 ? 501 GLU B N   1 
ATOM   5603 C CA  . GLU B 1 501 ? 162.023 221.893 169.439 1.00 132.81 ? 501 GLU B CA  1 
ATOM   5604 C C   . GLU B 1 501 ? 160.960 222.087 168.364 1.00 134.28 ? 501 GLU B C   1 
ATOM   5605 O O   . GLU B 1 501 ? 161.149 221.622 167.235 1.00 134.05 ? 501 GLU B O   1 
ATOM   5606 C CB  . GLU B 1 501 ? 161.901 220.492 170.041 1.00 132.63 ? 501 GLU B CB  1 
ATOM   5607 C CG  . GLU B 1 501 ? 163.120 220.048 170.835 1.00 133.47 ? 501 GLU B CG  1 
ATOM   5608 C CD  . GLU B 1 501 ? 162.812 218.905 171.781 1.00 135.00 ? 501 GLU B CD  1 
ATOM   5609 O OE1 . GLU B 1 501 ? 161.642 218.470 171.828 1.00 136.71 ? 501 GLU B OE1 1 
ATOM   5610 O OE2 . GLU B 1 501 ? 163.738 218.440 172.478 1.00 134.38 ? 501 GLU B OE2 1 
ATOM   5611 N N   . ARG B 1 502 ? 159.854 222.757 168.684 1.00 140.62 ? 502 ARG B N   1 
ATOM   5612 C CA  . ARG B 1 502 ? 158.816 223.059 167.709 1.00 140.27 ? 502 ARG B CA  1 
ATOM   5613 C C   . ARG B 1 502 ? 158.851 224.504 167.229 1.00 139.22 ? 502 ARG B C   1 
ATOM   5614 O O   . ARG B 1 502 ? 158.051 224.873 166.363 1.00 139.55 ? 502 ARG B O   1 
ATOM   5615 C CB  . ARG B 1 502 ? 157.435 222.736 168.291 1.00 139.11 ? 502 ARG B CB  1 
ATOM   5616 C CG  . ARG B 1 502 ? 157.267 221.277 168.685 1.00 140.51 ? 502 ARG B CG  1 
ATOM   5617 C CD  . ARG B 1 502 ? 156.160 221.094 169.708 1.00 140.11 ? 502 ARG B CD  1 
ATOM   5618 N NE  . ARG B 1 502 ? 156.023 219.700 170.111 1.00 140.27 ? 502 ARG B NE  1 
ATOM   5619 C CZ  . ARG B 1 502 ? 155.080 219.243 170.924 1.00 139.27 ? 502 ARG B CZ  1 
ATOM   5620 N NH1 . ARG B 1 502 ? 154.166 220.046 171.442 1.00 138.74 ? 502 ARG B NH1 1 
ATOM   5621 N NH2 . ARG B 1 502 ? 155.054 217.947 171.224 1.00 138.24 ? 502 ARG B NH2 1 
ATOM   5622 N N   . GLY B 1 503 ? 159.755 225.326 167.760 1.00 132.98 ? 503 GLY B N   1 
ATOM   5623 C CA  . GLY B 1 503 ? 159.924 226.689 167.292 1.00 132.05 ? 503 GLY B CA  1 
ATOM   5624 C C   . GLY B 1 503 ? 158.717 227.586 167.478 1.00 133.10 ? 503 GLY B C   1 
ATOM   5625 O O   . GLY B 1 503 ? 158.339 228.319 166.560 1.00 133.34 ? 503 GLY B O   1 
ATOM   5626 N N   . HIS B 1 504 ? 158.103 227.541 168.656 1.00 131.61 ? 504 HIS B N   1 
ATOM   5627 C CA  . HIS B 1 504 ? 156.941 228.366 168.948 1.00 131.09 ? 504 HIS B CA  1 
ATOM   5628 C C   . HIS B 1 504 ? 157.406 229.672 169.586 1.00 130.76 ? 504 HIS B C   1 
ATOM   5629 O O   . HIS B 1 504 ? 158.428 229.716 170.277 1.00 131.67 ? 504 HIS B O   1 
ATOM   5630 C CB  . HIS B 1 504 ? 155.966 227.596 169.851 1.00 131.62 ? 504 HIS B CB  1 
ATOM   5631 C CG  . HIS B 1 504 ? 154.805 228.402 170.355 1.00 130.84 ? 504 HIS B CG  1 
ATOM   5632 N ND1 . HIS B 1 504 ? 154.944 229.492 171.187 1.00 132.04 ? 504 HIS B ND1 1 
ATOM   5633 C CD2 . HIS B 1 504 ? 153.475 228.266 170.138 1.00 130.61 ? 504 HIS B CD2 1 
ATOM   5634 C CE1 . HIS B 1 504 ? 153.753 229.993 171.460 1.00 131.21 ? 504 HIS B CE1 1 
ATOM   5635 N NE2 . HIS B 1 504 ? 152.844 229.267 170.836 1.00 130.61 ? 504 HIS B NE2 1 
ATOM   5636 N N   . SER B 1 505 ? 156.646 230.744 169.336 1.00 130.14 ? 505 SER B N   1 
ATOM   5637 C CA  . SER B 1 505 ? 157.110 232.095 169.652 1.00 131.25 ? 505 SER B CA  1 
ATOM   5638 C C   . SER B 1 505 ? 157.382 232.296 171.140 1.00 132.91 ? 505 SER B C   1 
ATOM   5639 O O   . SER B 1 505 ? 158.279 233.066 171.500 1.00 133.42 ? 505 SER B O   1 
ATOM   5640 C CB  . SER B 1 505 ? 156.088 233.122 169.166 1.00 131.15 ? 505 SER B CB  1 
ATOM   5641 O OG  . SER B 1 505 ? 154.820 232.897 169.757 1.00 131.23 ? 505 SER B OG  1 
ATOM   5642 N N   . ASP B 1 506 ? 156.635 231.625 172.014 1.00 135.83 ? 506 ASP B N   1 
ATOM   5643 C CA  . ASP B 1 506 ? 156.790 231.783 173.455 1.00 135.08 ? 506 ASP B CA  1 
ATOM   5644 C C   . ASP B 1 506 ? 158.009 231.053 174.008 1.00 132.75 ? 506 ASP B C   1 
ATOM   5645 O O   . ASP B 1 506 ? 158.156 230.954 175.232 1.00 129.92 ? 506 ASP B O   1 
ATOM   5646 C CB  . ASP B 1 506 ? 155.528 231.304 174.178 1.00 134.55 ? 506 ASP B CB  1 
ATOM   5647 C CG  . ASP B 1 506 ? 154.329 232.193 173.909 1.00 135.43 ? 506 ASP B CG  1 
ATOM   5648 O OD1 . ASP B 1 506 ? 154.487 233.205 173.194 1.00 135.12 ? 506 ASP B OD1 1 
ATOM   5649 O OD2 . ASP B 1 506 ? 153.230 231.880 174.413 1.00 135.34 ? 506 ASP B OD2 1 
ATOM   5650 N N   . THR B 1 507 ? 158.881 230.541 173.135 1.00 130.01 ? 507 THR B N   1 
ATOM   5651 C CA  . THR B 1 507 ? 160.080 229.850 173.596 1.00 130.05 ? 507 THR B CA  1 
ATOM   5652 C C   . THR B 1 507 ? 160.982 230.787 174.389 1.00 132.21 ? 507 THR B C   1 
ATOM   5653 O O   . THR B 1 507 ? 161.516 230.409 175.436 1.00 133.68 ? 507 THR B O   1 
ATOM   5654 C CB  . THR B 1 507 ? 160.831 229.253 172.404 1.00 128.49 ? 507 THR B CB  1 
ATOM   5655 O OG1 . THR B 1 507 ? 160.098 228.134 171.889 1.00 127.77 ? 507 THR B OG1 1 
ATOM   5656 C CG2 . THR B 1 507 ? 162.222 228.793 172.815 1.00 128.13 ? 507 THR B CG2 1 
ATOM   5657 N N   . MET B 1 508 ? 161.159 232.021 173.909 1.00 131.19 ? 508 MET B N   1 
ATOM   5658 C CA  . MET B 1 508 ? 161.986 232.985 174.630 1.00 129.83 ? 508 MET B CA  1 
ATOM   5659 C C   . MET B 1 508 ? 161.388 233.348 175.985 1.00 128.41 ? 508 MET B C   1 
ATOM   5660 O O   . MET B 1 508 ? 162.120 233.444 176.978 1.00 127.64 ? 508 MET B O   1 
ATOM   5661 C CB  . MET B 1 508 ? 162.183 234.244 173.782 1.00 128.65 ? 508 MET B CB  1 
ATOM   5662 C CG  . MET B 1 508 ? 163.514 234.990 173.979 1.00 128.93 ? 508 MET B CG  1 
ATOM   5663 S SD  . MET B 1 508 ? 165.028 234.086 174.409 1.00 129.99 ? 508 MET B SD  1 
ATOM   5664 C CE  . MET B 1 508 ? 165.039 232.696 173.269 1.00 127.09 ? 508 MET B CE  1 
ATOM   5665 N N   . VAL B 1 509 ? 160.070 233.549 176.048 1.00 128.98 ? 509 VAL B N   1 
ATOM   5666 C CA  . VAL B 1 509 ? 159.425 233.874 177.317 1.00 131.26 ? 509 VAL B CA  1 
ATOM   5667 C C   . VAL B 1 509 ? 159.577 232.724 178.304 1.00 131.66 ? 509 VAL B C   1 
ATOM   5668 O O   . VAL B 1 509 ? 159.872 232.933 179.490 1.00 129.61 ? 509 VAL B O   1 
ATOM   5669 C CB  . VAL B 1 509 ? 157.945 234.227 177.085 1.00 129.92 ? 509 VAL B CB  1 
ATOM   5670 C CG1 . VAL B 1 509 ? 157.224 234.404 178.413 1.00 129.57 ? 509 VAL B CG1 1 
ATOM   5671 C CG2 . VAL B 1 509 ? 157.826 235.481 176.232 1.00 127.84 ? 509 VAL B CG2 1 
ATOM   5672 N N   . PHE B 1 510 ? 159.381 231.492 177.837 1.00 125.83 ? 510 PHE B N   1 
ATOM   5673 C CA  . PHE B 1 510 ? 159.515 230.344 178.719 1.00 123.72 ? 510 PHE B CA  1 
ATOM   5674 C C   . PHE B 1 510 ? 160.961 230.116 179.142 1.00 121.09 ? 510 PHE B C   1 
ATOM   5675 O O   . PHE B 1 510 ? 161.200 229.693 180.277 1.00 122.05 ? 510 PHE B O   1 
ATOM   5676 C CB  . PHE B 1 510 ? 158.951 229.100 178.033 1.00 122.15 ? 510 PHE B CB  1 
ATOM   5677 C CG  . PHE B 1 510 ? 157.614 228.677 178.569 1.00 123.75 ? 510 PHE B CG  1 
ATOM   5678 C CD1 . PHE B 1 510 ? 157.422 228.466 179.924 1.00 122.78 ? 510 PHE B CD1 1 
ATOM   5679 C CD2 . PHE B 1 510 ? 156.536 228.522 177.713 1.00 125.51 ? 510 PHE B CD2 1 
ATOM   5680 C CE1 . PHE B 1 510 ? 156.181 228.094 180.409 1.00 122.41 ? 510 PHE B CE1 1 
ATOM   5681 C CE2 . PHE B 1 510 ? 155.297 228.149 178.193 1.00 125.65 ? 510 PHE B CE2 1 
ATOM   5682 C CZ  . PHE B 1 510 ? 155.118 227.935 179.543 1.00 124.06 ? 510 PHE B CZ  1 
ATOM   5683 N N   . PHE B 1 511 ? 161.923 230.418 178.267 1.00 110.78 ? 511 PHE B N   1 
ATOM   5684 C CA  . PHE B 1 511 ? 163.334 230.403 178.633 1.00 111.24 ? 511 PHE B CA  1 
ATOM   5685 C C   . PHE B 1 511 ? 163.633 231.437 179.712 1.00 113.78 ? 511 PHE B C   1 
ATOM   5686 O O   . PHE B 1 511 ? 164.441 231.183 180.607 1.00 115.74 ? 511 PHE B O   1 
ATOM   5687 C CB  . PHE B 1 511 ? 164.189 230.643 177.381 1.00 111.82 ? 511 PHE B CB  1 
ATOM   5688 C CG  . PHE B 1 511 ? 165.669 230.779 177.649 1.00 111.05 ? 511 PHE B CG  1 
ATOM   5689 C CD1 . PHE B 1 511 ? 166.214 231.983 178.073 1.00 112.15 ? 511 PHE B CD1 1 
ATOM   5690 C CD2 . PHE B 1 511 ? 166.523 229.714 177.417 1.00 110.10 ? 511 PHE B CD2 1 
ATOM   5691 C CE1 . PHE B 1 511 ? 167.571 232.104 178.303 1.00 111.78 ? 511 PHE B CE1 1 
ATOM   5692 C CE2 . PHE B 1 511 ? 167.881 229.831 177.644 1.00 112.30 ? 511 PHE B CE2 1 
ATOM   5693 C CZ  . PHE B 1 511 ? 168.406 231.028 178.085 1.00 112.44 ? 511 PHE B CZ  1 
ATOM   5694 N N   . TYR B 1 512 ? 163.014 232.616 179.627 1.00 116.27 ? 512 TYR B N   1 
ATOM   5695 C CA  . TYR B 1 512 ? 163.187 233.617 180.677 1.00 116.33 ? 512 TYR B CA  1 
ATOM   5696 C C   . TYR B 1 512 ? 162.609 233.139 182.007 1.00 118.21 ? 512 TYR B C   1 
ATOM   5697 O O   . TYR B 1 512 ? 163.230 233.321 183.065 1.00 118.25 ? 512 TYR B O   1 
ATOM   5698 C CB  . TYR B 1 512 ? 162.541 234.935 180.253 1.00 118.55 ? 512 TYR B CB  1 
ATOM   5699 C CG  . TYR B 1 512 ? 162.922 236.109 181.121 1.00 121.94 ? 512 TYR B CG  1 
ATOM   5700 C CD1 . TYR B 1 512 ? 164.216 236.249 181.603 1.00 119.61 ? 512 TYR B CD1 1 
ATOM   5701 C CD2 . TYR B 1 512 ? 161.986 237.073 181.469 1.00 120.83 ? 512 TYR B CD2 1 
ATOM   5702 C CE1 . TYR B 1 512 ? 164.569 237.320 182.401 1.00 118.59 ? 512 TYR B CE1 1 
ATOM   5703 C CE2 . TYR B 1 512 ? 162.329 238.148 182.265 1.00 119.83 ? 512 TYR B CE2 1 
ATOM   5704 C CZ  . TYR B 1 512 ? 163.622 238.266 182.729 1.00 119.98 ? 512 TYR B CZ  1 
ATOM   5705 O OH  . TYR B 1 512 ? 163.970 239.334 183.523 1.00 118.38 ? 512 TYR B OH  1 
ATOM   5706 N N   . LEU B 1 513 ? 161.418 232.538 181.972 1.00 110.80 ? 513 LEU B N   1 
ATOM   5707 C CA  . LEU B 1 513 ? 160.831 231.991 183.194 1.00 110.28 ? 513 LEU B CA  1 
ATOM   5708 C C   . LEU B 1 513 ? 161.736 230.915 183.784 1.00 110.14 ? 513 LEU B C   1 
ATOM   5709 O O   . LEU B 1 513 ? 161.950 230.856 185.003 1.00 108.66 ? 513 LEU B O   1 
ATOM   5710 C CB  . LEU B 1 513 ? 159.439 231.430 182.898 1.00 108.92 ? 513 LEU B CB  1 
ATOM   5711 C CG  . LEU B 1 513 ? 158.224 232.247 183.352 1.00 111.93 ? 513 LEU B CG  1 
ATOM   5712 C CD1 . LEU B 1 513 ? 156.930 231.494 183.069 1.00 111.78 ? 513 LEU B CD1 1 
ATOM   5713 C CD2 . LEU B 1 513 ? 158.317 232.638 184.819 1.00 111.33 ? 513 LEU B CD2 1 
ATOM   5714 N N   . TRP B 1 514 ? 162.299 230.073 182.917 1.00 102.71 ? 514 TRP B N   1 
ATOM   5715 C CA  . TRP B 1 514 ? 163.267 229.063 183.324 1.00 98.45  ? 514 TRP B CA  1 
ATOM   5716 C C   . TRP B 1 514 ? 164.551 229.658 183.896 1.00 97.06  ? 514 TRP B C   1 
ATOM   5717 O O   . TRP B 1 514 ? 165.090 229.116 184.862 1.00 100.00 ? 514 TRP B O   1 
ATOM   5718 C CB  . TRP B 1 514 ? 163.530 228.146 182.131 1.00 99.24  ? 514 TRP B CB  1 
ATOM   5719 C CG  . TRP B 1 514 ? 164.669 227.212 182.268 1.00 96.97  ? 514 TRP B CG  1 
ATOM   5720 C CD1 . TRP B 1 514 ? 164.631 225.905 182.648 1.00 99.40  ? 514 TRP B CD1 1 
ATOM   5721 C CD2 . TRP B 1 514 ? 166.011 227.472 181.858 1.00 98.40  ? 514 TRP B CD2 1 
ATOM   5722 N NE1 . TRP B 1 514 ? 165.892 225.358 182.586 1.00 101.28 ? 514 TRP B NE1 1 
ATOM   5723 C CE2 . TRP B 1 514 ? 166.754 226.304 182.093 1.00 99.88  ? 514 TRP B CE2 1 
ATOM   5724 C CE3 . TRP B 1 514 ? 166.666 228.597 181.345 1.00 99.36  ? 514 TRP B CE3 1 
ATOM   5725 C CZ2 . TRP B 1 514 ? 168.120 226.228 181.831 1.00 98.60  ? 514 TRP B CZ2 1 
ATOM   5726 C CZ3 . TRP B 1 514 ? 168.017 228.514 181.085 1.00 101.61 ? 514 TRP B CZ3 1 
ATOM   5727 C CH2 . TRP B 1 514 ? 168.733 227.339 181.334 1.00 99.18  ? 514 TRP B CH2 1 
ATOM   5728 N N   . ILE B 1 515 ? 165.050 230.765 183.346 1.00 95.36  ? 515 ILE B N   1 
ATOM   5729 C CA  . ILE B 1 515 ? 166.261 231.372 183.902 1.00 96.09  ? 515 ILE B CA  1 
ATOM   5730 C C   . ILE B 1 515 ? 165.994 231.966 185.285 1.00 95.40  ? 515 ILE B C   1 
ATOM   5731 O O   . ILE B 1 515 ? 166.812 231.812 186.204 1.00 94.64  ? 515 ILE B O   1 
ATOM   5732 C CB  . ILE B 1 515 ? 166.864 232.410 182.925 1.00 100.27 ? 515 ILE B CB  1 
ATOM   5733 C CG1 . ILE B 1 515 ? 168.391 232.458 183.052 1.00 99.85  ? 515 ILE B CG1 1 
ATOM   5734 C CG2 . ILE B 1 515 ? 166.298 233.809 183.125 1.00 99.68  ? 515 ILE B CG2 1 
ATOM   5735 C CD1 . ILE B 1 515 ? 169.123 231.366 182.334 1.00 94.55  ? 515 ILE B CD1 1 
ATOM   5736 N N   . VAL B 1 516 ? 164.851 232.632 185.476 1.00 91.80  ? 516 VAL B N   1 
ATOM   5737 C CA  . VAL B 1 516 ? 164.594 233.219 186.790 1.00 92.88  ? 516 VAL B CA  1 
ATOM   5738 C C   . VAL B 1 516 ? 164.340 232.118 187.814 1.00 92.08  ? 516 VAL B C   1 
ATOM   5739 O O   . VAL B 1 516 ? 164.773 232.213 188.972 1.00 90.64  ? 516 VAL B O   1 
ATOM   5740 C CB  . VAL B 1 516 ? 163.442 234.244 186.736 1.00 95.01  ? 516 VAL B CB  1 
ATOM   5741 C CG1 . VAL B 1 516 ? 162.250 233.706 185.988 1.00 93.17  ? 516 VAL B CG1 1 
ATOM   5742 C CG2 . VAL B 1 516 ? 163.049 234.697 188.140 1.00 93.19  ? 516 VAL B CG2 1 
ATOM   5743 N N   . PHE B 1 517 ? 163.661 231.040 187.403 1.00 90.90  ? 517 PHE B N   1 
ATOM   5744 C CA  . PHE B 1 517 ? 163.488 229.908 188.305 1.00 89.59  ? 517 PHE B CA  1 
ATOM   5745 C C   . PHE B 1 517 ? 164.806 229.210 188.616 1.00 86.04  ? 517 PHE B C   1 
ATOM   5746 O O   . PHE B 1 517 ? 165.004 228.781 189.755 1.00 84.02  ? 517 PHE B O   1 
ATOM   5747 C CB  . PHE B 1 517 ? 162.480 228.917 187.725 1.00 90.70  ? 517 PHE B CB  1 
ATOM   5748 C CG  . PHE B 1 517 ? 161.119 229.016 188.350 1.00 91.91  ? 517 PHE B CG  1 
ATOM   5749 C CD1 . PHE B 1 517 ? 160.710 230.194 188.953 1.00 92.29  ? 517 PHE B CD1 1 
ATOM   5750 C CD2 . PHE B 1 517 ? 160.251 227.940 188.340 1.00 87.81  ? 517 PHE B CD2 1 
ATOM   5751 C CE1 . PHE B 1 517 ? 159.462 230.297 189.533 1.00 91.69  ? 517 PHE B CE1 1 
ATOM   5752 C CE2 . PHE B 1 517 ? 159.000 228.039 188.919 1.00 87.34  ? 517 PHE B CE2 1 
ATOM   5753 C CZ  . PHE B 1 517 ? 158.606 229.217 189.516 1.00 90.15  ? 517 PHE B CZ  1 
ATOM   5754 N N   . TYR B 1 518 ? 165.710 229.099 187.640 1.00 77.30  ? 518 TYR B N   1 
ATOM   5755 C CA  . TYR B 1 518 ? 167.059 228.612 187.901 1.00 70.89  ? 518 TYR B CA  1 
ATOM   5756 C C   . TYR B 1 518 ? 167.739 229.440 188.977 1.00 71.95  ? 518 TYR B C   1 
ATOM   5757 O O   . TYR B 1 518 ? 168.287 228.887 189.940 1.00 78.10  ? 518 TYR B O   1 
ATOM   5758 C CB  . TYR B 1 518 ? 167.867 228.624 186.594 1.00 75.20  ? 518 TYR B CB  1 
ATOM   5759 C CG  . TYR B 1 518 ? 169.386 228.681 186.716 1.00 73.17  ? 518 TYR B CG  1 
ATOM   5760 C CD1 . TYR B 1 518 ? 170.047 229.875 186.994 1.00 75.44  ? 518 TYR B CD1 1 
ATOM   5761 C CD2 . TYR B 1 518 ? 170.159 227.542 186.532 1.00 72.55  ? 518 TYR B CD2 1 
ATOM   5762 C CE1 . TYR B 1 518 ? 171.423 229.927 187.098 1.00 73.65  ? 518 TYR B CE1 1 
ATOM   5763 C CE2 . TYR B 1 518 ? 171.537 227.586 186.633 1.00 75.02  ? 518 TYR B CE2 1 
ATOM   5764 C CZ  . TYR B 1 518 ? 172.163 228.781 186.916 1.00 73.78  ? 518 TYR B CZ  1 
ATOM   5765 O OH  . TYR B 1 518 ? 173.534 228.832 187.019 1.00 73.24  ? 518 TYR B OH  1 
ATOM   5766 N N   . ILE B 1 519 ? 167.696 230.764 188.833 1.00 71.72  ? 519 ILE B N   1 
ATOM   5767 C CA  . ILE B 1 519 ? 168.379 231.633 189.784 1.00 73.36  ? 519 ILE B CA  1 
ATOM   5768 C C   . ILE B 1 519 ? 167.790 231.459 191.179 1.00 74.32  ? 519 ILE B C   1 
ATOM   5769 O O   . ILE B 1 519 ? 168.524 231.273 192.160 1.00 70.52  ? 519 ILE B O   1 
ATOM   5770 C CB  . ILE B 1 519 ? 168.314 233.098 189.315 1.00 77.95  ? 519 ILE B CB  1 
ATOM   5771 C CG1 . ILE B 1 519 ? 169.417 233.374 188.291 1.00 76.42  ? 519 ILE B CG1 1 
ATOM   5772 C CG2 . ILE B 1 519 ? 168.432 234.050 190.496 1.00 79.98  ? 519 ILE B CG2 1 
ATOM   5773 C CD1 . ILE B 1 519 ? 170.818 233.204 188.840 1.00 70.85  ? 519 ILE B CD1 1 
ATOM   5774 N N   . ILE B 1 520 ? 166.458 231.485 191.288 1.00 75.57  ? 520 ILE B N   1 
ATOM   5775 C CA  . ILE B 1 520 ? 165.839 231.426 192.611 1.00 74.56  ? 520 ILE B CA  1 
ATOM   5776 C C   . ILE B 1 520 ? 166.057 230.059 193.251 1.00 74.60  ? 520 ILE B C   1 
ATOM   5777 O O   . ILE B 1 520 ? 166.349 229.965 194.448 1.00 70.60  ? 520 ILE B O   1 
ATOM   5778 C CB  . ILE B 1 520 ? 164.345 231.803 192.542 1.00 72.37  ? 520 ILE B CB  1 
ATOM   5779 C CG1 . ILE B 1 520 ? 163.560 230.833 191.661 1.00 69.93  ? 520 ILE B CG1 1 
ATOM   5780 C CG2 . ILE B 1 520 ? 164.182 233.231 192.044 1.00 74.42  ? 520 ILE B CG2 1 
ATOM   5781 C CD1 . ILE B 1 520 ? 162.269 230.351 192.281 1.00 68.43  ? 520 ILE B CD1 1 
ATOM   5782 N N   . SER B 1 521 ? 165.938 228.979 192.471 1.00 72.53  ? 521 SER B N   1 
ATOM   5783 C CA  . SER B 1 521 ? 166.148 227.644 193.020 1.00 69.81  ? 521 SER B CA  1 
ATOM   5784 C C   . SER B 1 521 ? 167.581 227.460 193.497 1.00 64.71  ? 521 SER B C   1 
ATOM   5785 O O   . SER B 1 521 ? 167.814 226.968 194.611 1.00 65.98  ? 521 SER B O   1 
ATOM   5786 C CB  . SER B 1 521 ? 165.798 226.588 191.972 1.00 67.65  ? 521 SER B CB  1 
ATOM   5787 O OG  . SER B 1 521 ? 166.135 225.288 192.423 1.00 59.94  ? 521 SER B OG  1 
ATOM   5788 N N   . SER B 1 522 ? 168.554 227.849 192.671 1.00 57.67  ? 522 SER B N   1 
ATOM   5789 C CA  . SER B 1 522 ? 169.949 227.686 193.055 1.00 51.71  ? 522 SER B CA  1 
ATOM   5790 C C   . SER B 1 522 ? 170.275 228.517 194.287 1.00 57.15  ? 522 SER B C   1 
ATOM   5791 O O   . SER B 1 522 ? 170.960 228.045 195.201 1.00 61.68  ? 522 SER B O   1 
ATOM   5792 C CB  . SER B 1 522 ? 170.862 228.065 191.895 1.00 52.40  ? 522 SER B CB  1 
ATOM   5793 O OG  . SER B 1 522 ? 172.189 228.212 192.355 1.00 49.84  ? 522 SER B OG  1 
ATOM   5794 N N   . CYS B 1 523 ? 169.788 229.761 194.333 1.00 69.22  ? 523 CYS B N   1 
ATOM   5795 C CA  . CYS B 1 523 ? 170.037 230.605 195.496 1.00 72.06  ? 523 CYS B CA  1 
ATOM   5796 C C   . CYS B 1 523 ? 169.399 230.013 196.746 1.00 72.61  ? 523 CYS B C   1 
ATOM   5797 O O   . CYS B 1 523 ? 170.000 230.019 197.824 1.00 67.63  ? 523 CYS B O   1 
ATOM   5798 C CB  . CYS B 1 523 ? 169.515 232.018 195.237 1.00 76.91  ? 523 CYS B CB  1 
ATOM   5799 S SG  . CYS B 1 523 ? 170.790 233.202 194.749 1.00 88.47  ? 523 CYS B SG  1 
ATOM   5800 N N   . TYR B 1 524 ? 168.181 229.485 196.614 1.00 72.04  ? 524 TYR B N   1 
ATOM   5801 C CA  . TYR B 1 524 ? 167.486 228.877 197.743 1.00 70.08  ? 524 TYR B CA  1 
ATOM   5802 C C   . TYR B 1 524 ? 168.290 227.715 198.318 1.00 73.66  ? 524 TYR B C   1 
ATOM   5803 O O   . TYR B 1 524 ? 168.576 227.673 199.525 1.00 71.28  ? 524 TYR B O   1 
ATOM   5804 C CB  . TYR B 1 524 ? 166.107 228.415 197.267 1.00 64.46  ? 524 TYR B CB  1 
ATOM   5805 C CG  . TYR B 1 524 ? 165.059 228.157 198.324 1.00 68.69  ? 524 TYR B CG  1 
ATOM   5806 C CD1 . TYR B 1 524 ? 165.368 228.147 199.677 1.00 74.92  ? 524 TYR B CD1 1 
ATOM   5807 C CD2 . TYR B 1 524 ? 163.740 227.939 197.954 1.00 68.80  ? 524 TYR B CD2 1 
ATOM   5808 C CE1 . TYR B 1 524 ? 164.388 227.909 200.627 1.00 79.98  ? 524 TYR B CE1 1 
ATOM   5809 C CE2 . TYR B 1 524 ? 162.762 227.706 198.887 1.00 72.30  ? 524 TYR B CE2 1 
ATOM   5810 C CZ  . TYR B 1 524 ? 163.086 227.691 200.220 1.00 78.17  ? 524 TYR B CZ  1 
ATOM   5811 O OH  . TYR B 1 524 ? 162.091 227.456 201.136 1.00 73.46  ? 524 TYR B OH  1 
ATOM   5812 N N   . THR B 1 525 ? 168.684 226.772 197.456 1.00 70.30  ? 525 THR B N   1 
ATOM   5813 C CA  . THR B 1 525 ? 169.435 225.616 197.938 1.00 58.27  ? 525 THR B CA  1 
ATOM   5814 C C   . THR B 1 525 ? 170.798 226.020 198.487 1.00 56.83  ? 525 THR B C   1 
ATOM   5815 O O   . THR B 1 525 ? 171.239 225.482 199.508 1.00 67.86  ? 525 THR B O   1 
ATOM   5816 C CB  . THR B 1 525 ? 169.595 224.569 196.836 1.00 58.92  ? 525 THR B CB  1 
ATOM   5817 O OG1 . THR B 1 525 ? 170.651 224.956 195.947 1.00 65.40  ? 525 THR B OG1 1 
ATOM   5818 C CG2 . THR B 1 525 ? 168.297 224.365 196.072 1.00 64.21  ? 525 THR B CG2 1 
ATOM   5819 N N   . LEU B 1 526 ? 171.484 226.959 197.828 1.00 48.30  ? 526 LEU B N   1 
ATOM   5820 C CA  . LEU B 1 526 ? 172.791 227.390 198.313 1.00 53.69  ? 526 LEU B CA  1 
ATOM   5821 C C   . LEU B 1 526 ? 172.680 228.041 199.685 1.00 61.00  ? 526 LEU B C   1 
ATOM   5822 O O   . LEU B 1 526 ? 173.470 227.742 200.588 1.00 66.55  ? 526 LEU B O   1 
ATOM   5823 C CB  . LEU B 1 526 ? 173.427 228.355 197.312 1.00 55.32  ? 526 LEU B CB  1 
ATOM   5824 C CG  . LEU B 1 526 ? 174.690 229.109 197.741 1.00 58.19  ? 526 LEU B CG  1 
ATOM   5825 C CD1 . LEU B 1 526 ? 175.747 228.161 198.293 1.00 65.59  ? 526 LEU B CD1 1 
ATOM   5826 C CD2 . LEU B 1 526 ? 175.248 229.921 196.583 1.00 59.49  ? 526 LEU B CD2 1 
ATOM   5827 N N   . ILE B 1 527 ? 171.699 228.929 199.863 1.00 70.07  ? 527 ILE B N   1 
ATOM   5828 C CA  . ILE B 1 527 ? 171.536 229.614 201.141 1.00 69.83  ? 527 ILE B CA  1 
ATOM   5829 C C   . ILE B 1 527 ? 171.211 228.614 202.240 1.00 68.58  ? 527 ILE B C   1 
ATOM   5830 O O   . ILE B 1 527 ? 171.748 228.697 203.350 1.00 67.05  ? 527 ILE B O   1 
ATOM   5831 C CB  . ILE B 1 527 ? 170.463 230.713 201.036 1.00 70.52  ? 527 ILE B CB  1 
ATOM   5832 C CG1 . ILE B 1 527 ? 170.961 231.862 200.157 1.00 68.32  ? 527 ILE B CG1 1 
ATOM   5833 C CG2 . ILE B 1 527 ? 170.090 231.228 202.416 1.00 70.58  ? 527 ILE B CG2 1 
ATOM   5834 C CD1 . ILE B 1 527 ? 169.853 232.715 199.582 1.00 68.42  ? 527 ILE B CD1 1 
ATOM   5835 N N   . TRP B 1 528 ? 170.331 227.650 201.957 1.00 68.65  ? 528 TRP B N   1 
ATOM   5836 C CA  . TRP B 1 528 ? 170.011 226.673 202.992 1.00 65.69  ? 528 TRP B CA  1 
ATOM   5837 C C   . TRP B 1 528 ? 171.230 225.821 203.329 1.00 69.56  ? 528 TRP B C   1 
ATOM   5838 O O   . TRP B 1 528 ? 171.570 225.650 204.505 1.00 70.61  ? 528 TRP B O   1 
ATOM   5839 C CB  . TRP B 1 528 ? 168.818 225.812 202.573 1.00 63.01  ? 528 TRP B CB  1 
ATOM   5840 C CG  . TRP B 1 528 ? 168.317 224.881 203.657 1.00 66.95  ? 528 TRP B CG  1 
ATOM   5841 C CD1 . TRP B 1 528 ? 169.059 224.213 204.592 1.00 74.14  ? 528 TRP B CD1 1 
ATOM   5842 C CD2 . TRP B 1 528 ? 166.951 224.616 203.978 1.00 68.83  ? 528 TRP B CD2 1 
ATOM   5843 N NE1 . TRP B 1 528 ? 168.242 223.502 205.431 1.00 76.98  ? 528 TRP B NE1 1 
ATOM   5844 C CE2 . TRP B 1 528 ? 166.940 223.739 205.081 1.00 72.85  ? 528 TRP B CE2 1 
ATOM   5845 C CE3 . TRP B 1 528 ? 165.734 225.017 203.426 1.00 68.94  ? 528 TRP B CE3 1 
ATOM   5846 C CZ2 . TRP B 1 528 ? 165.762 223.257 205.637 1.00 71.72  ? 528 TRP B CZ2 1 
ATOM   5847 C CZ3 . TRP B 1 528 ? 164.574 224.541 203.979 1.00 68.90  ? 528 TRP B CZ3 1 
ATOM   5848 C CH2 . TRP B 1 528 ? 164.591 223.672 205.074 1.00 70.01  ? 528 TRP B CH2 1 
ATOM   5849 N N   . ASP B 1 529 ? 171.923 225.305 202.309 1.00 62.44  ? 529 ASP B N   1 
ATOM   5850 C CA  . ASP B 1 529 ? 173.119 224.506 202.555 1.00 55.06  ? 529 ASP B CA  1 
ATOM   5851 C C   . ASP B 1 529 ? 174.158 225.281 203.352 1.00 61.95  ? 529 ASP B C   1 
ATOM   5852 O O   . ASP B 1 529 ? 174.886 224.693 204.159 1.00 67.10  ? 529 ASP B O   1 
ATOM   5853 C CB  . ASP B 1 529 ? 173.716 224.036 201.228 1.00 53.10  ? 529 ASP B CB  1 
ATOM   5854 C CG  . ASP B 1 529 ? 172.952 222.877 200.623 1.00 57.09  ? 529 ASP B CG  1 
ATOM   5855 O OD1 . ASP B 1 529 ? 171.980 222.410 201.253 1.00 59.31  ? 529 ASP B OD1 1 
ATOM   5856 O OD2 . ASP B 1 529 ? 173.322 222.435 199.516 1.00 53.57  ? 529 ASP B OD2 1 
ATOM   5857 N N   . LEU B 1 530 ? 174.239 226.595 203.148 1.00 62.60  ? 530 LEU B N   1 
ATOM   5858 C CA  . LEU B 1 530 ? 175.240 227.427 203.799 1.00 62.69  ? 530 LEU B CA  1 
ATOM   5859 C C   . LEU B 1 530 ? 174.803 227.916 205.175 1.00 66.66  ? 530 LEU B C   1 
ATOM   5860 O O   . LEU B 1 530 ? 175.652 228.331 205.971 1.00 66.91  ? 530 LEU B O   1 
ATOM   5861 C CB  . LEU B 1 530 ? 175.567 228.623 202.904 1.00 67.63  ? 530 LEU B CB  1 
ATOM   5862 C CG  . LEU B 1 530 ? 177.036 228.898 202.603 1.00 69.04  ? 530 LEU B CG  1 
ATOM   5863 C CD1 . LEU B 1 530 ? 177.735 227.611 202.200 1.00 64.56  ? 530 LEU B CD1 1 
ATOM   5864 C CD2 . LEU B 1 530 ? 177.140 229.939 201.504 1.00 76.45  ? 530 LEU B CD2 1 
ATOM   5865 N N   . LYS B 1 531 ? 173.506 227.872 205.477 1.00 78.80  ? 531 LYS B N   1 
ATOM   5866 C CA  . LYS B 1 531 ? 172.996 228.464 206.707 1.00 80.43  ? 531 LYS B CA  1 
ATOM   5867 C C   . LYS B 1 531 ? 172.516 227.419 207.705 1.00 81.83  ? 531 LYS B C   1 
ATOM   5868 O O   . LYS B 1 531 ? 172.907 227.454 208.876 1.00 79.76  ? 531 LYS B O   1 
ATOM   5869 C CB  . LYS B 1 531 ? 171.858 229.436 206.380 1.00 77.59  ? 531 LYS B CB  1 
ATOM   5870 C CG  . LYS B 1 531 ? 171.041 229.904 207.581 1.00 78.86  ? 531 LYS B CG  1 
ATOM   5871 C CD  . LYS B 1 531 ? 171.883 230.619 208.629 1.00 78.04  ? 531 LYS B CD  1 
ATOM   5872 C CE  . LYS B 1 531 ? 172.552 231.857 208.057 1.00 82.45  ? 531 LYS B CE  1 
ATOM   5873 N NZ  . LYS B 1 531 ? 173.261 232.633 209.110 1.00 82.39  ? 531 LYS B NZ  1 
ATOM   5874 N N   . MET B 1 532 ? 171.659 226.497 207.270 1.00 80.54  ? 532 MET B N   1 
ATOM   5875 C CA  . MET B 1 532 ? 171.066 225.553 208.208 1.00 79.50  ? 532 MET B CA  1 
ATOM   5876 C C   . MET B 1 532 ? 171.724 224.178 208.139 1.00 82.86  ? 532 MET B C   1 
ATOM   5877 O O   . MET B 1 532 ? 171.982 223.561 209.177 1.00 80.00  ? 532 MET B O   1 
ATOM   5878 C CB  . MET B 1 532 ? 169.561 225.437 207.955 1.00 75.43  ? 532 MET B CB  1 
ATOM   5879 C CG  . MET B 1 532 ? 168.738 226.470 208.710 1.00 83.55  ? 532 MET B CG  1 
ATOM   5880 S SD  . MET B 1 532 ? 168.001 225.803 210.212 1.00 94.51  ? 532 MET B SD  1 
ATOM   5881 C CE  . MET B 1 532 ? 166.878 224.598 209.522 1.00 80.13  ? 532 MET B CE  1 
ATOM   5882 N N   . ASP B 1 533 ? 171.998 223.685 206.929 1.00 68.41  ? 533 ASP B N   1 
ATOM   5883 C CA  . ASP B 1 533 ? 172.620 222.372 206.788 1.00 55.81  ? 533 ASP B CA  1 
ATOM   5884 C C   . ASP B 1 533 ? 174.027 222.364 207.373 1.00 61.35  ? 533 ASP B C   1 
ATOM   5885 O O   . ASP B 1 533 ? 174.386 221.471 208.149 1.00 68.78  ? 533 ASP B O   1 
ATOM   5886 C CB  . ASP B 1 533 ? 172.643 221.959 205.317 1.00 57.24  ? 533 ASP B CB  1 
ATOM   5887 C CG  . ASP B 1 533 ? 171.447 221.111 204.932 1.00 64.08  ? 533 ASP B CG  1 
ATOM   5888 O OD1 . ASP B 1 533 ? 170.570 220.893 205.794 1.00 63.00  ? 533 ASP B OD1 1 
ATOM   5889 O OD2 . ASP B 1 533 ? 171.387 220.658 203.770 1.00 66.27  ? 533 ASP B OD2 1 
ATOM   5890 N N   . TRP B 1 534 ? 174.841 223.355 207.010 1.00 53.71  ? 534 TRP B N   1 
ATOM   5891 C CA  . TRP B 1 534 ? 176.183 223.461 207.570 1.00 55.94  ? 534 TRP B CA  1 
ATOM   5892 C C   . TRP B 1 534 ? 176.163 224.167 208.920 1.00 57.49  ? 534 TRP B C   1 
ATOM   5893 O O   . TRP B 1 534 ? 176.973 223.861 209.803 1.00 55.33  ? 534 TRP B O   1 
ATOM   5894 C CB  . TRP B 1 534 ? 177.104 224.194 206.594 1.00 53.78  ? 534 TRP B CB  1 
ATOM   5895 C CG  . TRP B 1 534 ? 177.403 223.421 205.344 1.00 53.82  ? 534 TRP B CG  1 
ATOM   5896 C CD1 . TRP B 1 534 ? 176.761 222.304 204.896 1.00 52.86  ? 534 TRP B CD1 1 
ATOM   5897 C CD2 . TRP B 1 534 ? 178.412 223.720 204.372 1.00 54.43  ? 534 TRP B CD2 1 
ATOM   5898 N NE1 . TRP B 1 534 ? 177.313 221.884 203.712 1.00 47.87  ? 534 TRP B NE1 1 
ATOM   5899 C CE2 . TRP B 1 534 ? 178.327 222.737 203.368 1.00 49.53  ? 534 TRP B CE2 1 
ATOM   5900 C CE3 . TRP B 1 534 ? 179.380 224.721 204.256 1.00 56.54  ? 534 TRP B CE3 1 
ATOM   5901 C CZ2 . TRP B 1 534 ? 179.173 222.725 202.262 1.00 50.68  ? 534 TRP B CZ2 1 
ATOM   5902 C CZ3 . TRP B 1 534 ? 180.218 224.707 203.157 1.00 59.36  ? 534 TRP B CZ3 1 
ATOM   5903 C CH2 . TRP B 1 534 ? 180.110 223.716 202.176 1.00 56.54  ? 534 TRP B CH2 1 
ATOM   5904 N N   . GLY B 1 535 ? 175.245 225.108 209.099 1.00 71.08  ? 535 GLY B N   1 
ATOM   5905 C CA  . GLY B 1 535 ? 175.174 225.889 210.313 1.00 73.42  ? 535 GLY B CA  1 
ATOM   5906 C C   . GLY B 1 535 ? 176.021 227.142 210.328 1.00 77.03  ? 535 GLY B C   1 
ATOM   5907 O O   . GLY B 1 535 ? 176.008 227.858 211.335 1.00 80.75  ? 535 GLY B O   1 
ATOM   5908 N N   . LEU B 1 536 ? 176.733 227.440 209.245 1.00 84.08  ? 536 LEU B N   1 
ATOM   5909 C CA  . LEU B 1 536 ? 177.676 228.546 209.222 1.00 85.16  ? 536 LEU B CA  1 
ATOM   5910 C C   . LEU B 1 536 ? 176.955 229.890 209.282 1.00 90.59  ? 536 LEU B C   1 
ATOM   5911 O O   . LEU B 1 536 ? 175.725 229.967 209.358 1.00 91.63  ? 536 LEU B O   1 
ATOM   5912 C CB  . LEU B 1 536 ? 178.550 228.479 207.969 1.00 86.95  ? 536 LEU B CB  1 
ATOM   5913 C CG  . LEU B 1 536 ? 179.361 227.196 207.781 1.00 84.10  ? 536 LEU B CG  1 
ATOM   5914 C CD1 . LEU B 1 536 ? 180.293 227.321 206.586 1.00 83.11  ? 536 LEU B CD1 1 
ATOM   5915 C CD2 . LEU B 1 536 ? 180.138 226.858 209.043 1.00 85.46  ? 536 LEU B CD2 1 
ATOM   5916 N N   . PHE B 1 537 ? 177.753 230.961 209.250 1.00 99.60  ? 537 PHE B N   1 
ATOM   5917 C CA  . PHE B 1 537 ? 177.264 232.332 209.356 1.00 98.95  ? 537 PHE B CA  1 
ATOM   5918 C C   . PHE B 1 537 ? 176.497 232.532 210.658 1.00 99.31  ? 537 PHE B C   1 
ATOM   5919 O O   . PHE B 1 537 ? 175.506 233.268 210.697 1.00 97.92  ? 537 PHE B O   1 
ATOM   5920 C CB  . PHE B 1 537 ? 176.382 232.702 208.156 1.00 94.27  ? 537 PHE B CB  1 
ATOM   5921 C CG  . PHE B 1 537 ? 177.119 232.766 206.842 1.00 95.03  ? 537 PHE B CG  1 
ATOM   5922 C CD1 . PHE B 1 537 ? 178.477 232.503 206.767 1.00 98.59  ? 537 PHE B CD1 1 
ATOM   5923 C CD2 . PHE B 1 537 ? 176.443 233.092 205.678 1.00 97.24  ? 537 PHE B CD2 1 
ATOM   5924 C CE1 . PHE B 1 537 ? 179.144 232.564 205.559 1.00 99.37  ? 537 PHE B CE1 1 
ATOM   5925 C CE2 . PHE B 1 537 ? 177.105 233.155 204.467 1.00 99.35  ? 537 PHE B CE2 1 
ATOM   5926 C CZ  . PHE B 1 537 ? 178.458 232.890 204.408 1.00 98.10  ? 537 PHE B CZ  1 
ATOM   5927 N N   . ASP B 1 538 ? 176.949 231.880 211.725 1.00 107.86 ? 538 ASP B N   1 
ATOM   5928 C CA  . ASP B 1 538 ? 176.288 232.002 213.016 1.00 107.37 ? 538 ASP B CA  1 
ATOM   5929 C C   . ASP B 1 538 ? 176.591 233.355 213.649 1.00 107.55 ? 538 ASP B C   1 
ATOM   5930 O O   . ASP B 1 538 ? 177.722 233.846 213.595 1.00 106.48 ? 538 ASP B O   1 
ATOM   5931 C CB  . ASP B 1 538 ? 176.730 230.872 213.945 1.00 107.99 ? 538 ASP B CB  1 
ATOM   5932 C CG  . ASP B 1 538 ? 176.329 231.110 215.387 1.00 111.29 ? 538 ASP B CG  1 
ATOM   5933 O OD1 . ASP B 1 538 ? 175.132 231.363 215.639 1.00 113.21 ? 538 ASP B OD1 1 
ATOM   5934 O OD2 . ASP B 1 538 ? 177.209 231.040 216.269 1.00 112.14 ? 538 ASP B OD2 1 
ATOM   5935 N N   . LYS B 1 539 ? 175.565 233.960 214.252 1.00 111.24 ? 539 LYS B N   1 
ATOM   5936 C CA  . LYS B 1 539 ? 175.746 235.252 214.906 1.00 112.02 ? 539 LYS B CA  1 
ATOM   5937 C C   . LYS B 1 539 ? 176.623 235.142 216.147 1.00 111.39 ? 539 LYS B C   1 
ATOM   5938 O O   . LYS B 1 539 ? 177.393 236.063 216.442 1.00 111.76 ? 539 LYS B O   1 
ATOM   5939 C CB  . LYS B 1 539 ? 174.387 235.854 215.266 1.00 111.33 ? 539 LYS B CB  1 
ATOM   5940 C CG  . LYS B 1 539 ? 173.500 236.233 214.075 1.00 113.09 ? 539 LYS B CG  1 
ATOM   5941 C CD  . LYS B 1 539 ? 174.167 237.230 213.127 1.00 113.18 ? 539 LYS B CD  1 
ATOM   5942 C CE  . LYS B 1 539 ? 174.727 236.558 211.876 1.00 109.89 ? 539 LYS B CE  1 
ATOM   5943 N NZ  . LYS B 1 539 ? 175.433 237.528 210.994 1.00 107.69 ? 539 LYS B NZ  1 
ATOM   5944 N N   . ASN B 1 540 ? 176.523 234.034 216.881 1.00 106.88 ? 540 ASN B N   1 
ATOM   5945 C CA  . ASN B 1 540 ? 177.305 233.819 218.092 1.00 106.73 ? 540 ASN B CA  1 
ATOM   5946 C C   . ASN B 1 540 ? 178.714 233.307 217.807 1.00 108.52 ? 540 ASN B C   1 
ATOM   5947 O O   . ASN B 1 540 ? 179.362 232.779 218.718 1.00 110.10 ? 540 ASN B O   1 
ATOM   5948 C CB  . ASN B 1 540 ? 176.577 232.842 219.019 1.00 105.28 ? 540 ASN B CB  1 
ATOM   5949 C CG  . ASN B 1 540 ? 175.153 233.269 219.313 1.00 106.95 ? 540 ASN B CG  1 
ATOM   5950 O OD1 . ASN B 1 540 ? 174.705 234.325 218.869 1.00 108.82 ? 540 ASN B OD1 1 
ATOM   5951 N ND2 . ASN B 1 540 ? 174.432 232.445 220.065 1.00 107.60 ? 540 ASN B ND2 1 
ATOM   5952 N N   . ALA B 1 541 ? 179.193 233.447 216.568 1.00 103.87 ? 541 ALA B N   1 
ATOM   5953 C CA  . ALA B 1 541 ? 180.498 232.903 216.206 1.00 103.51 ? 541 ALA B CA  1 
ATOM   5954 C C   . ALA B 1 541 ? 181.623 233.568 216.987 1.00 105.43 ? 541 ALA B C   1 
ATOM   5955 O O   . ALA B 1 541 ? 182.524 232.888 217.492 1.00 105.43 ? 541 ALA B O   1 
ATOM   5956 C CB  . ALA B 1 541 ? 180.729 233.060 214.705 1.00 104.50 ? 541 ALA B CB  1 
ATOM   5957 N N   . GLY B 1 542 ? 181.592 234.892 217.097 1.00 115.39 ? 542 GLY B N   1 
ATOM   5958 C CA  . GLY B 1 542 ? 182.658 235.610 217.765 1.00 115.31 ? 542 GLY B CA  1 
ATOM   5959 C C   . GLY B 1 542 ? 183.927 235.689 216.941 1.00 117.12 ? 542 GLY B C   1 
ATOM   5960 O O   . GLY B 1 542 ? 183.972 236.393 215.927 1.00 117.03 ? 542 GLY B O   1 
ATOM   5961 N N   . GLU B 1 543 ? 184.968 234.972 217.371 1.00 125.57 ? 543 GLU B N   1 
ATOM   5962 C CA  . GLU B 1 543 ? 186.246 235.021 216.667 1.00 125.46 ? 543 GLU B CA  1 
ATOM   5963 C C   . GLU B 1 543 ? 186.135 234.441 215.261 1.00 126.73 ? 543 GLU B C   1 
ATOM   5964 O O   . GLU B 1 543 ? 186.686 235.005 214.308 1.00 125.13 ? 543 GLU B O   1 
ATOM   5965 C CB  . GLU B 1 543 ? 187.316 234.279 217.470 1.00 123.77 ? 543 GLU B CB  1 
ATOM   5966 C CG  . GLU B 1 543 ? 188.617 233.997 216.715 1.00 125.77 ? 543 GLU B CG  1 
ATOM   5967 C CD  . GLU B 1 543 ? 189.240 235.232 216.077 1.00 126.87 ? 543 GLU B CD  1 
ATOM   5968 O OE1 . GLU B 1 543 ? 188.988 236.360 216.553 1.00 126.52 ? 543 GLU B OE1 1 
ATOM   5969 O OE2 . GLU B 1 543 ? 189.987 235.071 215.089 1.00 126.49 ? 543 GLU B OE2 1 
ATOM   5970 N N   . ASN B 1 544 ? 185.431 233.319 215.111 1.00 116.30 ? 544 ASN B N   1 
ATOM   5971 C CA  . ASN B 1 544 ? 185.306 232.666 213.813 1.00 113.01 ? 544 ASN B CA  1 
ATOM   5972 C C   . ASN B 1 544 ? 184.538 233.545 212.834 1.00 111.81 ? 544 ASN B C   1 
ATOM   5973 O O   . ASN B 1 544 ? 183.342 233.794 213.017 1.00 108.92 ? 544 ASN B O   1 
ATOM   5974 C CB  . ASN B 1 544 ? 184.620 231.307 213.960 1.00 109.60 ? 544 ASN B CB  1 
ATOM   5975 C CG  . ASN B 1 544 ? 185.374 230.371 214.883 1.00 109.50 ? 544 ASN B CG  1 
ATOM   5976 O OD1 . ASN B 1 544 ? 184.834 229.898 215.883 1.00 108.27 ? 544 ASN B OD1 1 
ATOM   5977 N ND2 . ASN B 1 544 ? 186.631 230.099 214.553 1.00 109.97 ? 544 ASN B ND2 1 
ATOM   5978 N N   . THR B 1 545 ? 185.217 234.017 211.792 1.00 114.51 ? 545 THR B N   1 
ATOM   5979 C CA  . THR B 1 545 ? 184.609 234.925 210.828 1.00 114.85 ? 545 THR B CA  1 
ATOM   5980 C C   . THR B 1 545 ? 183.694 234.148 209.889 1.00 115.23 ? 545 THR B C   1 
ATOM   5981 O O   . THR B 1 545 ? 184.143 233.226 209.199 1.00 116.36 ? 545 THR B O   1 
ATOM   5982 C CB  . THR B 1 545 ? 185.688 235.661 210.038 1.00 115.60 ? 545 THR B CB  1 
ATOM   5983 O OG1 . THR B 1 545 ? 186.237 234.784 209.046 1.00 114.95 ? 545 THR B OG1 1 
ATOM   5984 C CG2 . THR B 1 545 ? 186.800 236.128 210.965 1.00 115.07 ? 545 THR B CG2 1 
ATOM   5985 N N   . PHE B 1 546 ? 182.413 234.528 209.862 1.00 114.20 ? 546 PHE B N   1 
ATOM   5986 C CA  . PHE B 1 546 ? 181.421 233.936 208.960 1.00 113.40 ? 546 PHE B CA  1 
ATOM   5987 C C   . PHE B 1 546 ? 181.346 232.419 209.126 1.00 114.85 ? 546 PHE B C   1 
ATOM   5988 O O   . PHE B 1 546 ? 181.209 231.675 208.153 1.00 117.36 ? 546 PHE B O   1 
ATOM   5989 C CB  . PHE B 1 546 ? 181.704 234.312 207.503 1.00 113.82 ? 546 PHE B CB  1 
ATOM   5990 C CG  . PHE B 1 546 ? 182.390 235.640 207.342 1.00 113.86 ? 546 PHE B CG  1 
ATOM   5991 C CD1 . PHE B 1 546 ? 181.726 236.818 207.641 1.00 114.19 ? 546 PHE B CD1 1 
ATOM   5992 C CD2 . PHE B 1 546 ? 183.699 235.709 206.896 1.00 113.77 ? 546 PHE B CD2 1 
ATOM   5993 C CE1 . PHE B 1 546 ? 182.354 238.040 207.496 1.00 114.15 ? 546 PHE B CE1 1 
ATOM   5994 C CE2 . PHE B 1 546 ? 184.333 236.928 206.749 1.00 114.55 ? 546 PHE B CE2 1 
ATOM   5995 C CZ  . PHE B 1 546 ? 183.659 238.095 207.049 1.00 114.96 ? 546 PHE B CZ  1 
ATOM   5996 N N   . LEU B 1 547 ? 181.431 231.958 210.371 1.00 102.43 ? 547 LEU B N   1 
ATOM   5997 C CA  . LEU B 1 547 ? 181.404 230.536 210.689 1.00 100.53 ? 547 LEU B CA  1 
ATOM   5998 C C   . LEU B 1 547 ? 180.575 230.349 211.955 1.00 100.12 ? 547 LEU B C   1 
ATOM   5999 O O   . LEU B 1 547 ? 179.803 231.227 212.352 1.00 103.11 ? 547 LEU B O   1 
ATOM   6000 C CB  . LEU B 1 547 ? 182.825 229.976 210.839 1.00 103.91 ? 547 LEU B CB  1 
ATOM   6001 C CG  . LEU B 1 547 ? 183.713 229.984 209.592 1.00 101.88 ? 547 LEU B CG  1 
ATOM   6002 C CD1 . LEU B 1 547 ? 185.139 229.588 209.940 1.00 100.13 ? 547 LEU B CD1 1 
ATOM   6003 C CD2 . LEU B 1 547 ? 183.143 229.066 208.524 1.00 98.00  ? 547 LEU B CD2 1 
ATOM   6004 N N   . ARG B 1 548 ? 180.712 229.182 212.574 1.00 87.72  ? 548 ARG B N   1 
ATOM   6005 C CA  . ARG B 1 548 ? 180.047 228.883 213.832 1.00 87.98  ? 548 ARG B CA  1 
ATOM   6006 C C   . ARG B 1 548 ? 180.941 229.239 215.016 1.00 88.50  ? 548 ARG B C   1 
ATOM   6007 O O   . ARG B 1 548 ? 182.132 229.519 214.867 1.00 87.37  ? 548 ARG B O   1 
ATOM   6008 C CB  . ARG B 1 548 ? 179.662 227.407 213.895 1.00 88.04  ? 548 ARG B CB  1 
ATOM   6009 C CG  . ARG B 1 548 ? 178.311 227.095 213.292 1.00 86.89  ? 548 ARG B CG  1 
ATOM   6010 C CD  . ARG B 1 548 ? 178.214 225.629 212.936 1.00 86.49  ? 548 ARG B CD  1 
ATOM   6011 N NE  . ARG B 1 548 ? 179.472 225.152 212.379 1.00 87.35  ? 548 ARG B NE  1 
ATOM   6012 C CZ  . ARG B 1 548 ? 179.637 223.972 211.799 1.00 84.42  ? 548 ARG B CZ  1 
ATOM   6013 N NH1 . ARG B 1 548 ? 178.643 223.106 211.702 1.00 79.83  ? 548 ARG B NH1 1 
ATOM   6014 N NH2 . ARG B 1 548 ? 180.828 223.655 211.303 1.00 86.48  ? 548 ARG B NH2 1 
ATOM   6015 N N   . GLU B 1 549 ? 180.339 229.226 216.208 1.00 91.50  ? 549 GLU B N   1 
ATOM   6016 C CA  . GLU B 1 549 ? 181.094 229.520 217.421 1.00 91.52  ? 549 GLU B CA  1 
ATOM   6017 C C   . GLU B 1 549 ? 182.163 228.464 217.677 1.00 92.55  ? 549 GLU B C   1 
ATOM   6018 O O   . GLU B 1 549 ? 183.294 228.792 218.054 1.00 92.66  ? 549 GLU B O   1 
ATOM   6019 C CB  . GLU B 1 549 ? 180.146 229.624 218.616 1.00 91.60  ? 549 GLU B CB  1 
ATOM   6020 C CG  . GLU B 1 549 ? 180.847 229.721 219.962 1.00 92.57  ? 549 GLU B CG  1 
ATOM   6021 C CD  . GLU B 1 549 ? 179.988 229.215 221.103 1.00 93.34  ? 549 GLU B CD  1 
ATOM   6022 O OE1 . GLU B 1 549 ? 179.440 228.099 220.988 1.00 93.94  ? 549 GLU B OE1 1 
ATOM   6023 O OE2 . GLU B 1 549 ? 179.861 229.934 222.117 1.00 95.34  ? 549 GLU B OE2 1 
ATOM   6024 N N   . GLU B 1 550 ? 181.826 227.194 217.472 1.00 91.48  ? 550 GLU B N   1 
ATOM   6025 C CA  . GLU B 1 550 ? 182.742 226.087 217.697 1.00 88.10  ? 550 GLU B CA  1 
ATOM   6026 C C   . GLU B 1 550 ? 182.857 225.253 216.429 1.00 89.86  ? 550 GLU B C   1 
ATOM   6027 O O   . GLU B 1 550 ? 181.878 225.075 215.698 1.00 91.41  ? 550 GLU B O   1 
ATOM   6028 C CB  . GLU B 1 550 ? 182.280 225.214 218.877 1.00 84.16  ? 550 GLU B CB  1 
ATOM   6029 C CG  . GLU B 1 550 ? 181.059 224.327 218.614 1.00 86.39  ? 550 GLU B CG  1 
ATOM   6030 C CD  . GLU B 1 550 ? 179.746 225.092 218.478 1.00 90.23  ? 550 GLU B CD  1 
ATOM   6031 O OE1 . GLU B 1 550 ? 179.764 226.315 218.229 1.00 91.23  ? 550 GLU B OE1 1 
ATOM   6032 O OE2 . GLU B 1 550 ? 178.682 224.457 218.632 1.00 90.29  ? 550 GLU B OE2 1 
ATOM   6033 N N   . ILE B 1 551 ? 184.063 224.758 216.164 1.00 82.25  ? 551 ILE B N   1 
ATOM   6034 C CA  . ILE B 1 551 ? 184.351 223.970 214.973 1.00 82.08  ? 551 ILE B CA  1 
ATOM   6035 C C   . ILE B 1 551 ? 185.084 222.705 215.391 1.00 81.58  ? 551 ILE B C   1 
ATOM   6036 O O   . ILE B 1 551 ? 185.797 222.692 216.401 1.00 81.84  ? 551 ILE B O   1 
ATOM   6037 C CB  . ILE B 1 551 ? 185.184 224.767 213.949 1.00 80.88  ? 551 ILE B CB  1 
ATOM   6038 C CG1 . ILE B 1 551 ? 186.362 225.454 214.643 1.00 85.30  ? 551 ILE B CG1 1 
ATOM   6039 C CG2 . ILE B 1 551 ? 184.314 225.786 213.232 1.00 75.82  ? 551 ILE B CG2 1 
ATOM   6040 C CD1 . ILE B 1 551 ? 187.220 226.278 213.715 1.00 82.75  ? 551 ILE B CD1 1 
ATOM   6041 N N   . VAL B 1 552 ? 184.907 221.641 214.614 1.00 71.17  ? 552 VAL B N   1 
ATOM   6042 C CA  . VAL B 1 552 ? 185.537 220.358 214.890 1.00 68.00  ? 552 VAL B CA  1 
ATOM   6043 C C   . VAL B 1 552 ? 186.742 220.118 213.990 1.00 71.43  ? 552 VAL B C   1 
ATOM   6044 O O   . VAL B 1 552 ? 187.781 219.646 214.452 1.00 74.71  ? 552 VAL B O   1 
ATOM   6045 C CB  . VAL B 1 552 ? 184.500 219.222 214.750 1.00 67.09  ? 552 VAL B CB  1 
ATOM   6046 C CG1 . VAL B 1 552 ? 185.189 217.870 214.653 1.00 64.77  ? 552 VAL B CG1 1 
ATOM   6047 C CG2 . VAL B 1 552 ? 183.526 219.248 215.918 1.00 67.38  ? 552 VAL B CG2 1 
ATOM   6048 N N   . TYR B 1 553 ? 186.621 220.449 212.707 1.00 70.17  ? 553 TYR B N   1 
ATOM   6049 C CA  . TYR B 1 553 ? 187.683 220.174 211.755 1.00 68.47  ? 553 TYR B CA  1 
ATOM   6050 C C   . TYR B 1 553 ? 188.898 221.056 212.049 1.00 70.22  ? 553 TYR B C   1 
ATOM   6051 O O   . TYR B 1 553 ? 188.754 222.185 212.526 1.00 71.82  ? 553 TYR B O   1 
ATOM   6052 C CB  . TYR B 1 553 ? 187.175 220.397 210.333 1.00 65.19  ? 553 TYR B CB  1 
ATOM   6053 C CG  . TYR B 1 553 ? 186.061 219.442 209.960 1.00 64.75  ? 553 TYR B CG  1 
ATOM   6054 C CD1 . TYR B 1 553 ? 185.930 218.217 210.601 1.00 62.35  ? 553 TYR B CD1 1 
ATOM   6055 C CD2 . TYR B 1 553 ? 185.126 219.774 208.990 1.00 71.00  ? 553 TYR B CD2 1 
ATOM   6056 C CE1 . TYR B 1 553 ? 184.912 217.344 210.278 1.00 59.13  ? 553 TYR B CE1 1 
ATOM   6057 C CE2 . TYR B 1 553 ? 184.102 218.905 208.660 1.00 71.80  ? 553 TYR B CE2 1 
ATOM   6058 C CZ  . TYR B 1 553 ? 184.001 217.692 209.308 1.00 59.55  ? 553 TYR B CZ  1 
ATOM   6059 O OH  . TYR B 1 553 ? 182.985 216.821 208.988 1.00 57.31  ? 553 TYR B OH  1 
ATOM   6060 N N   . PRO B 1 554 ? 190.111 220.558 211.781 1.00 84.71  ? 554 PRO B N   1 
ATOM   6061 C CA  . PRO B 1 554 ? 191.312 221.228 212.316 1.00 86.49  ? 554 PRO B CA  1 
ATOM   6062 C C   . PRO B 1 554 ? 191.525 222.649 211.818 1.00 85.32  ? 554 PRO B C   1 
ATOM   6063 O O   . PRO B 1 554 ? 192.043 223.480 212.575 1.00 84.68  ? 554 PRO B O   1 
ATOM   6064 C CB  . PRO B 1 554 ? 192.467 220.309 211.886 1.00 84.88  ? 554 PRO B CB  1 
ATOM   6065 C CG  . PRO B 1 554 ? 191.870 219.165 211.155 1.00 83.94  ? 554 PRO B CG  1 
ATOM   6066 C CD  . PRO B 1 554 ? 190.430 219.424 210.898 1.00 82.30  ? 554 PRO B CD  1 
ATOM   6067 N N   . GLN B 1 555 ? 191.149 222.965 210.581 1.00 95.12  ? 555 GLN B N   1 
ATOM   6068 C CA  . GLN B 1 555 ? 191.475 224.258 209.995 1.00 99.16  ? 555 GLN B CA  1 
ATOM   6069 C C   . GLN B 1 555 ? 190.218 224.951 209.491 1.00 97.79  ? 555 GLN B C   1 
ATOM   6070 O O   . GLN B 1 555 ? 189.336 224.314 208.908 1.00 98.25  ? 555 GLN B O   1 
ATOM   6071 C CB  . GLN B 1 555 ? 192.482 224.109 208.847 1.00 99.69  ? 555 GLN B CB  1 
ATOM   6072 C CG  . GLN B 1 555 ? 193.083 225.423 208.373 1.00 100.76 ? 555 GLN B CG  1 
ATOM   6073 C CD  . GLN B 1 555 ? 194.039 226.028 209.384 1.00 101.60 ? 555 GLN B CD  1 
ATOM   6074 O OE1 . GLN B 1 555 ? 194.538 225.340 210.275 1.00 97.42  ? 555 GLN B OE1 1 
ATOM   6075 N NE2 . GLN B 1 555 ? 194.298 227.324 209.251 1.00 100.93 ? 555 GLN B NE2 1 
ATOM   6076 N N   . LYS B 1 556 ? 190.146 226.265 209.722 1.00 96.88  ? 556 LYS B N   1 
ATOM   6077 C CA  . LYS B 1 556 ? 189.043 227.072 209.216 1.00 96.94  ? 556 LYS B CA  1 
ATOM   6078 C C   . LYS B 1 556 ? 189.140 227.325 207.718 1.00 97.55  ? 556 LYS B C   1 
ATOM   6079 O O   . LYS B 1 556 ? 188.113 227.580 207.077 1.00 98.34  ? 556 LYS B O   1 
ATOM   6080 C CB  . LYS B 1 556 ? 188.985 228.410 209.958 1.00 98.17  ? 556 LYS B CB  1 
ATOM   6081 C CG  . LYS B 1 556 ? 189.234 228.304 211.453 1.00 98.40  ? 556 LYS B CG  1 
ATOM   6082 C CD  . LYS B 1 556 ? 189.108 229.657 212.138 1.00 99.56  ? 556 LYS B CD  1 
ATOM   6083 C CE  . LYS B 1 556 ? 189.815 230.750 211.351 1.00 100.62 ? 556 LYS B CE  1 
ATOM   6084 N NZ  . LYS B 1 556 ? 190.089 231.949 212.189 1.00 99.61  ? 556 LYS B NZ  1 
ATOM   6085 N N   . ALA B 1 557 ? 190.349 227.274 207.151 1.00 90.96  ? 557 ALA B N   1 
ATOM   6086 C CA  . ALA B 1 557 ? 190.493 227.398 205.705 1.00 91.36  ? 557 ALA B CA  1 
ATOM   6087 C C   . ALA B 1 557 ? 189.733 226.299 204.979 1.00 90.85  ? 557 ALA B C   1 
ATOM   6088 O O   . ALA B 1 557 ? 189.223 226.519 203.874 1.00 84.96  ? 557 ALA B O   1 
ATOM   6089 C CB  . ALA B 1 557 ? 191.970 227.372 205.316 1.00 88.40  ? 557 ALA B CB  1 
ATOM   6090 N N   . TYR B 1 558 ? 189.649 225.112 205.584 1.00 88.18  ? 558 TYR B N   1 
ATOM   6091 C CA  . TYR B 1 558 ? 188.808 224.053 205.037 1.00 86.11  ? 558 TYR B CA  1 
ATOM   6092 C C   . TYR B 1 558 ? 187.359 224.511 204.951 1.00 82.24  ? 558 TYR B C   1 
ATOM   6093 O O   . TYR B 1 558 ? 186.700 224.341 203.919 1.00 84.13  ? 558 TYR B O   1 
ATOM   6094 C CB  . TYR B 1 558 ? 188.926 222.799 205.904 1.00 87.72  ? 558 TYR B CB  1 
ATOM   6095 C CG  . TYR B 1 558 ? 190.180 221.991 205.661 1.00 88.21  ? 558 TYR B CG  1 
ATOM   6096 C CD1 . TYR B 1 558 ? 191.037 222.299 204.614 1.00 84.11  ? 558 TYR B CD1 1 
ATOM   6097 C CD2 . TYR B 1 558 ? 190.512 220.928 206.489 1.00 85.84  ? 558 TYR B CD2 1 
ATOM   6098 C CE1 . TYR B 1 558 ? 192.185 221.564 204.393 1.00 83.51  ? 558 TYR B CE1 1 
ATOM   6099 C CE2 . TYR B 1 558 ? 191.658 220.189 206.277 1.00 83.61  ? 558 TYR B CE2 1 
ATOM   6100 C CZ  . TYR B 1 558 ? 192.491 220.510 205.228 1.00 85.89  ? 558 TYR B CZ  1 
ATOM   6101 O OH  . TYR B 1 558 ? 193.634 219.775 205.012 1.00 89.89  ? 558 TYR B OH  1 
ATOM   6102 N N   . TYR B 1 559 ? 186.856 225.124 206.025 1.00 76.52  ? 559 TYR B N   1 
ATOM   6103 C CA  . TYR B 1 559 ? 185.492 225.642 206.023 1.00 80.14  ? 559 TYR B CA  1 
ATOM   6104 C C   . TYR B 1 559 ? 185.307 226.685 204.928 1.00 86.16  ? 559 TYR B C   1 
ATOM   6105 O O   . TYR B 1 559 ? 184.320 226.654 204.181 1.00 82.92  ? 559 TYR B O   1 
ATOM   6106 C CB  . TYR B 1 559 ? 185.160 226.246 207.388 1.00 78.84  ? 559 TYR B CB  1 
ATOM   6107 C CG  . TYR B 1 559 ? 185.031 225.240 208.507 1.00 78.44  ? 559 TYR B CG  1 
ATOM   6108 C CD1 . TYR B 1 559 ? 186.155 224.665 209.085 1.00 81.80  ? 559 TYR B CD1 1 
ATOM   6109 C CD2 . TYR B 1 559 ? 183.785 224.875 208.995 1.00 78.08  ? 559 TYR B CD2 1 
ATOM   6110 C CE1 . TYR B 1 559 ? 186.039 223.748 210.111 1.00 83.18  ? 559 TYR B CE1 1 
ATOM   6111 C CE2 . TYR B 1 559 ? 183.661 223.959 210.017 1.00 79.01  ? 559 TYR B CE2 1 
ATOM   6112 C CZ  . TYR B 1 559 ? 184.789 223.399 210.573 1.00 79.89  ? 559 TYR B CZ  1 
ATOM   6113 O OH  . TYR B 1 559 ? 184.665 222.486 211.594 1.00 77.95  ? 559 TYR B OH  1 
ATOM   6114 N N   . TYR B 1 560 ? 186.258 227.615 204.811 1.00 97.52  ? 560 TYR B N   1 
ATOM   6115 C CA  . TYR B 1 560 ? 186.117 228.684 203.827 1.00 94.02  ? 560 TYR B CA  1 
ATOM   6116 C C   . TYR B 1 560 ? 186.088 228.126 202.409 1.00 92.29  ? 560 TYR B C   1 
ATOM   6117 O O   . TYR B 1 560 ? 185.138 228.376 201.650 1.00 89.35  ? 560 TYR B O   1 
ATOM   6118 C CB  . TYR B 1 560 ? 187.240 229.708 203.994 1.00 93.17  ? 560 TYR B CB  1 
ATOM   6119 C CG  . TYR B 1 560 ? 187.198 230.437 205.319 1.00 94.00  ? 560 TYR B CG  1 
ATOM   6120 C CD1 . TYR B 1 560 ? 186.031 231.049 205.758 1.00 94.13  ? 560 TYR B CD1 1 
ATOM   6121 C CD2 . TYR B 1 560 ? 188.325 230.521 206.126 1.00 91.56  ? 560 TYR B CD2 1 
ATOM   6122 C CE1 . TYR B 1 560 ? 185.985 231.717 206.966 1.00 92.72  ? 560 TYR B CE1 1 
ATOM   6123 C CE2 . TYR B 1 560 ? 188.289 231.188 207.336 1.00 92.85  ? 560 TYR B CE2 1 
ATOM   6124 C CZ  . TYR B 1 560 ? 187.117 231.784 207.751 1.00 93.52  ? 560 TYR B CZ  1 
ATOM   6125 O OH  . TYR B 1 560 ? 187.076 232.450 208.954 1.00 92.42  ? 560 TYR B OH  1 
ATOM   6126 N N   . CYS B 1 561 ? 187.096 227.322 202.055 1.00 90.51  ? 561 CYS B N   1 
ATOM   6127 C CA  . CYS B 1 561 ? 187.139 226.744 200.718 1.00 92.89  ? 561 CYS B CA  1 
ATOM   6128 C C   . CYS B 1 561 ? 185.911 225.886 200.460 1.00 92.55  ? 561 CYS B C   1 
ATOM   6129 O O   . CYS B 1 561 ? 185.435 225.800 199.323 1.00 93.56  ? 561 CYS B O   1 
ATOM   6130 C CB  . CYS B 1 561 ? 188.424 225.938 200.526 1.00 90.74  ? 561 CYS B CB  1 
ATOM   6131 S SG  . CYS B 1 561 ? 188.492 224.376 201.422 1.00 96.34  ? 561 CYS B SG  1 
ATOM   6132 N N   . ALA B 1 562 ? 185.355 225.278 201.511 1.00 78.00  ? 562 ALA B N   1 
ATOM   6133 C CA  . ALA B 1 562 ? 184.083 224.584 201.367 1.00 73.27  ? 562 ALA B CA  1 
ATOM   6134 C C   . ALA B 1 562 ? 182.975 225.549 200.966 1.00 76.00  ? 562 ALA B C   1 
ATOM   6135 O O   . ALA B 1 562 ? 182.134 225.223 200.123 1.00 83.97  ? 562 ALA B O   1 
ATOM   6136 C CB  . ALA B 1 562 ? 183.726 223.863 202.665 1.00 72.70  ? 562 ALA B CB  1 
ATOM   6137 N N   . ILE B 1 563 ? 182.950 226.744 201.568 1.00 75.71  ? 563 ILE B N   1 
ATOM   6138 C CA  . ILE B 1 563 ? 181.918 227.716 201.195 1.00 82.58  ? 563 ILE B CA  1 
ATOM   6139 C C   . ILE B 1 563 ? 182.038 228.116 199.727 1.00 82.77  ? 563 ILE B C   1 
ATOM   6140 O O   . ILE B 1 563 ? 181.040 228.117 198.996 1.00 75.80  ? 563 ILE B O   1 
ATOM   6141 C CB  . ILE B 1 563 ? 181.918 228.949 202.123 1.00 82.36  ? 563 ILE B CB  1 
ATOM   6142 C CG1 . ILE B 1 563 ? 182.101 228.567 203.591 1.00 81.29  ? 563 ILE B CG1 1 
ATOM   6143 C CG2 . ILE B 1 563 ? 180.661 229.777 201.928 1.00 81.46  ? 563 ILE B CG2 1 
ATOM   6144 C CD1 . ILE B 1 563 ? 182.872 229.581 204.398 1.00 83.73  ? 563 ILE B CD1 1 
ATOM   6145 N N   . ILE B 1 564 ? 183.245 228.467 199.264 1.00 84.31  ? 564 ILE B N   1 
ATOM   6146 C CA  . ILE B 1 564 ? 183.326 228.870 197.851 1.00 81.72  ? 564 ILE B CA  1 
ATOM   6147 C C   . ILE B 1 564 ? 183.027 227.688 196.927 1.00 79.78  ? 564 ILE B C   1 
ATOM   6148 O O   . ILE B 1 564 ? 182.361 227.846 195.893 1.00 81.56  ? 564 ILE B O   1 
ATOM   6149 C CB  . ILE B 1 564 ? 184.657 229.556 197.461 1.00 83.14  ? 564 ILE B CB  1 
ATOM   6150 C CG1 . ILE B 1 564 ? 185.214 230.529 198.505 1.00 83.48  ? 564 ILE B CG1 1 
ATOM   6151 C CG2 . ILE B 1 564 ? 184.507 230.277 196.127 1.00 84.19  ? 564 ILE B CG2 1 
ATOM   6152 C CD1 . ILE B 1 564 ? 186.119 229.944 199.502 1.00 81.66  ? 564 ILE B CD1 1 
ATOM   6153 N N   . GLU B 1 565 ? 183.507 226.492 197.277 1.00 69.50  ? 565 GLU B N   1 
ATOM   6154 C CA  . GLU B 1 565 ? 183.223 225.308 196.471 1.00 68.32  ? 565 GLU B CA  1 
ATOM   6155 C C   . GLU B 1 565 ? 181.723 225.071 196.355 1.00 67.82  ? 565 GLU B C   1 
ATOM   6156 O O   . GLU B 1 565 ? 181.202 224.830 195.259 1.00 75.58  ? 565 GLU B O   1 
ATOM   6157 C CB  . GLU B 1 565 ? 183.927 224.099 197.091 1.00 71.84  ? 565 GLU B CB  1 
ATOM   6158 C CG  . GLU B 1 565 ? 183.863 222.812 196.289 1.00 74.49  ? 565 GLU B CG  1 
ATOM   6159 C CD  . GLU B 1 565 ? 182.741 221.904 196.749 1.00 72.34  ? 565 GLU B CD  1 
ATOM   6160 O OE1 . GLU B 1 565 ? 181.859 222.379 197.493 1.00 67.05  ? 565 GLU B OE1 1 
ATOM   6161 O OE2 . GLU B 1 565 ? 182.752 220.710 196.385 1.00 75.30  ? 565 GLU B OE2 1 
ATOM   6162 N N   . ASP B 1 566 ? 181.012 225.155 197.481 1.00 65.70  ? 566 ASP B N   1 
ATOM   6163 C CA  . ASP B 1 566 ? 179.567 224.967 197.478 1.00 71.00  ? 566 ASP B CA  1 
ATOM   6164 C C   . ASP B 1 566 ? 178.888 226.055 196.654 1.00 78.58  ? 566 ASP B C   1 
ATOM   6165 O O   . ASP B 1 566 ? 177.948 225.777 195.900 1.00 75.36  ? 566 ASP B O   1 
ATOM   6166 C CB  . ASP B 1 566 ? 179.067 224.950 198.929 1.00 71.36  ? 566 ASP B CB  1 
ATOM   6167 C CG  . ASP B 1 566 ? 177.580 224.634 199.061 1.00 74.86  ? 566 ASP B CG  1 
ATOM   6168 O OD1 . ASP B 1 566 ? 176.777 225.012 198.192 1.00 74.53  ? 566 ASP B OD1 1 
ATOM   6169 O OD2 . ASP B 1 566 ? 177.209 224.007 200.075 1.00 76.06  ? 566 ASP B OD2 1 
ATOM   6170 N N   . VAL B 1 567 ? 179.370 227.296 196.765 1.00 80.01  ? 567 VAL B N   1 
ATOM   6171 C CA  . VAL B 1 567 ? 178.757 228.399 196.030 1.00 77.08  ? 567 VAL B CA  1 
ATOM   6172 C C   . VAL B 1 567 ? 178.839 228.162 194.527 1.00 72.92  ? 567 VAL B C   1 
ATOM   6173 O O   . VAL B 1 567 ? 177.841 228.310 193.811 1.00 74.22  ? 567 VAL B O   1 
ATOM   6174 C CB  . VAL B 1 567 ? 179.409 229.736 196.429 1.00 76.97  ? 567 VAL B CB  1 
ATOM   6175 C CG1 . VAL B 1 567 ? 179.091 230.809 195.400 1.00 77.66  ? 567 VAL B CG1 1 
ATOM   6176 C CG2 . VAL B 1 567 ? 178.929 230.167 197.805 1.00 74.08  ? 567 VAL B CG2 1 
ATOM   6177 N N   . ILE B 1 568 ? 180.016 227.786 194.021 1.00 68.68  ? 568 ILE B N   1 
ATOM   6178 C CA  . ILE B 1 568 ? 180.124 227.541 192.582 1.00 69.81  ? 568 ILE B CA  1 
ATOM   6179 C C   . ILE B 1 568 ? 179.343 226.293 192.179 1.00 70.19  ? 568 ILE B C   1 
ATOM   6180 O O   . ILE B 1 568 ? 178.669 226.271 191.137 1.00 76.56  ? 568 ILE B O   1 
ATOM   6181 C CB  . ILE B 1 568 ? 181.594 227.452 192.131 1.00 70.73  ? 568 ILE B CB  1 
ATOM   6182 C CG1 . ILE B 1 568 ? 182.481 228.381 192.956 1.00 69.40  ? 568 ILE B CG1 1 
ATOM   6183 C CG2 . ILE B 1 568 ? 181.712 227.771 190.648 1.00 74.94  ? 568 ILE B CG2 1 
ATOM   6184 C CD1 . ILE B 1 568 ? 183.908 228.454 192.463 1.00 72.07  ? 568 ILE B CD1 1 
ATOM   6185 N N   . LEU B 1 569 ? 179.414 225.234 192.979 1.00 66.03  ? 569 LEU B N   1 
ATOM   6186 C CA  . LEU B 1 569 ? 178.830 223.982 192.529 1.00 67.08  ? 569 LEU B CA  1 
ATOM   6187 C C   . LEU B 1 569 ? 177.320 223.907 192.709 1.00 68.41  ? 569 LEU B C   1 
ATOM   6188 O O   . LEU B 1 569 ? 176.703 223.019 192.124 1.00 69.98  ? 569 LEU B O   1 
ATOM   6189 C CB  . LEU B 1 569 ? 179.509 222.799 193.219 1.00 66.77  ? 569 LEU B CB  1 
ATOM   6190 C CG  . LEU B 1 569 ? 180.920 222.588 192.665 1.00 66.78  ? 569 LEU B CG  1 
ATOM   6191 C CD1 . LEU B 1 569 ? 181.740 221.666 193.539 1.00 65.64  ? 569 LEU B CD1 1 
ATOM   6192 C CD2 . LEU B 1 569 ? 180.851 222.061 191.244 1.00 64.26  ? 569 LEU B CD2 1 
ATOM   6193 N N   . ARG B 1 570 ? 176.693 224.828 193.445 1.00 62.13  ? 570 ARG B N   1 
ATOM   6194 C CA  . ARG B 1 570 ? 175.236 224.923 193.364 1.00 59.86  ? 570 ARG B CA  1 
ATOM   6195 C C   . ARG B 1 570 ? 174.807 225.374 191.972 1.00 68.41  ? 570 ARG B C   1 
ATOM   6196 O O   . ARG B 1 570 ? 173.901 224.787 191.360 1.00 67.64  ? 570 ARG B O   1 
ATOM   6197 C CB  . ARG B 1 570 ? 174.696 225.884 194.422 1.00 61.77  ? 570 ARG B CB  1 
ATOM   6198 C CG  . ARG B 1 570 ? 174.870 225.421 195.853 1.00 60.23  ? 570 ARG B CG  1 
ATOM   6199 C CD  . ARG B 1 570 ? 174.485 223.968 196.080 1.00 67.97  ? 570 ARG B CD  1 
ATOM   6200 N NE  . ARG B 1 570 ? 173.149 223.638 195.602 1.00 68.31  ? 570 ARG B NE  1 
ATOM   6201 C CZ  . ARG B 1 570 ? 172.545 222.480 195.833 1.00 68.74  ? 570 ARG B CZ  1 
ATOM   6202 N NH1 . ARG B 1 570 ? 173.125 221.529 196.544 1.00 64.77  ? 570 ARG B NH1 1 
ATOM   6203 N NH2 . ARG B 1 570 ? 171.326 222.275 195.346 1.00 67.02  ? 570 ARG B NH2 1 
ATOM   6204 N N   . PHE B 1 571 ? 175.460 226.421 191.454 1.00 77.31  ? 571 PHE B N   1 
ATOM   6205 C CA  . PHE B 1 571 ? 175.228 226.847 190.079 1.00 73.20  ? 571 PHE B CA  1 
ATOM   6206 C C   . PHE B 1 571 ? 175.536 225.715 189.110 1.00 75.00  ? 571 PHE B C   1 
ATOM   6207 O O   . PHE B 1 571 ? 174.781 225.474 188.159 1.00 78.73  ? 571 PHE B O   1 
ATOM   6208 C CB  . PHE B 1 571 ? 176.096 228.063 189.745 1.00 73.54  ? 571 PHE B CB  1 
ATOM   6209 C CG  . PHE B 1 571 ? 175.771 229.299 190.542 1.00 74.16  ? 571 PHE B CG  1 
ATOM   6210 C CD1 . PHE B 1 571 ? 174.586 229.405 191.242 1.00 68.24  ? 571 PHE B CD1 1 
ATOM   6211 C CD2 . PHE B 1 571 ? 176.666 230.355 190.593 1.00 77.63  ? 571 PHE B CD2 1 
ATOM   6212 C CE1 . PHE B 1 571 ? 174.293 230.539 191.976 1.00 68.16  ? 571 PHE B CE1 1 
ATOM   6213 C CE2 . PHE B 1 571 ? 176.379 231.493 191.324 1.00 74.31  ? 571 PHE B CE2 1 
ATOM   6214 C CZ  . PHE B 1 571 ? 175.190 231.584 192.016 1.00 71.08  ? 571 PHE B CZ  1 
ATOM   6215 N N   . ALA B 1 572 ? 176.649 225.014 189.339 1.00 72.52  ? 572 ALA B N   1 
ATOM   6216 C CA  . ALA B 1 572 ? 177.023 223.904 188.466 1.00 70.75  ? 572 ALA B CA  1 
ATOM   6217 C C   . ALA B 1 572 ? 175.973 222.796 188.485 1.00 75.61  ? 572 ALA B C   1 
ATOM   6218 O O   . ALA B 1 572 ? 175.628 222.240 187.438 1.00 75.47  ? 572 ALA B O   1 
ATOM   6219 C CB  . ALA B 1 572 ? 178.390 223.357 188.870 1.00 73.25  ? 572 ALA B CB  1 
ATOM   6220 N N   . TRP B 1 573 ? 175.453 222.463 189.668 1.00 83.68  ? 573 TRP B N   1 
ATOM   6221 C CA  . TRP B 1 573 ? 174.445 221.416 189.786 1.00 84.21  ? 573 TRP B CA  1 
ATOM   6222 C C   . TRP B 1 573 ? 173.165 221.802 189.059 1.00 82.88  ? 573 TRP B C   1 
ATOM   6223 O O   . TRP B 1 573 ? 172.606 221.001 188.297 1.00 78.12  ? 573 TRP B O   1 
ATOM   6224 C CB  . TRP B 1 573 ? 174.178 221.149 191.269 1.00 81.99  ? 573 TRP B CB  1 
ATOM   6225 C CG  . TRP B 1 573 ? 173.123 220.133 191.579 1.00 83.27  ? 573 TRP B CG  1 
ATOM   6226 C CD1 . TRP B 1 573 ? 173.254 218.779 191.523 1.00 81.92  ? 573 TRP B CD1 1 
ATOM   6227 C CD2 . TRP B 1 573 ? 171.791 220.388 192.044 1.00 84.84  ? 573 TRP B CD2 1 
ATOM   6228 N NE1 . TRP B 1 573 ? 172.082 218.172 191.903 1.00 85.82  ? 573 TRP B NE1 1 
ATOM   6229 C CE2 . TRP B 1 573 ? 171.168 219.137 192.229 1.00 84.67  ? 573 TRP B CE2 1 
ATOM   6230 C CE3 . TRP B 1 573 ? 171.061 221.550 192.308 1.00 81.90  ? 573 TRP B CE3 1 
ATOM   6231 C CZ2 . TRP B 1 573 ? 169.851 219.016 192.668 1.00 82.30  ? 573 TRP B CZ2 1 
ATOM   6232 C CZ3 . TRP B 1 573 ? 169.753 221.428 192.744 1.00 82.55  ? 573 TRP B CZ3 1 
ATOM   6233 C CH2 . TRP B 1 573 ? 169.162 220.170 192.919 1.00 82.53  ? 573 TRP B CH2 1 
ATOM   6234 N N   . THR B 1 574 ? 172.699 223.037 189.264 1.00 84.43  ? 574 THR B N   1 
ATOM   6235 C CA  . THR B 1 574 ? 171.477 223.474 188.596 1.00 84.01  ? 574 THR B CA  1 
ATOM   6236 C C   . THR B 1 574 ? 171.650 223.500 187.080 1.00 81.55  ? 574 THR B C   1 
ATOM   6237 O O   . THR B 1 574 ? 170.765 223.045 186.338 1.00 81.35  ? 574 THR B O   1 
ATOM   6238 C CB  . THR B 1 574 ? 171.057 224.849 189.114 1.00 83.19  ? 574 THR B CB  1 
ATOM   6239 O OG1 . THR B 1 574 ? 172.183 225.735 189.089 1.00 79.99  ? 574 THR B OG1 1 
ATOM   6240 C CG2 . THR B 1 574 ? 170.533 224.738 190.537 1.00 83.15  ? 574 THR B CG2 1 
ATOM   6241 N N   . ILE B 1 575 ? 172.787 224.013 186.599 1.00 84.19  ? 575 ILE B N   1 
ATOM   6242 C CA  . ILE B 1 575 ? 172.985 224.068 185.156 1.00 84.60  ? 575 ILE B CA  1 
ATOM   6243 C C   . ILE B 1 575 ? 173.142 222.665 184.582 1.00 87.95  ? 575 ILE B C   1 
ATOM   6244 O O   . ILE B 1 575 ? 172.722 222.412 183.451 1.00 86.02  ? 575 ILE B O   1 
ATOM   6245 C CB  . ILE B 1 575 ? 174.173 224.981 184.787 1.00 85.50  ? 575 ILE B CB  1 
ATOM   6246 C CG1 . ILE B 1 575 ? 174.182 225.253 183.282 1.00 84.12  ? 575 ILE B CG1 1 
ATOM   6247 C CG2 . ILE B 1 575 ? 175.496 224.372 185.201 1.00 85.74  ? 575 ILE B CG2 1 
ATOM   6248 C CD1 . ILE B 1 575 ? 175.336 226.112 182.820 1.00 82.74  ? 575 ILE B CD1 1 
ATOM   6249 N N   . GLN B 1 576 ? 173.726 221.729 185.340 1.00 93.10  ? 576 GLN B N   1 
ATOM   6250 C CA  . GLN B 1 576 ? 173.820 220.351 184.868 1.00 91.87  ? 576 GLN B CA  1 
ATOM   6251 C C   . GLN B 1 576 ? 172.440 219.723 184.733 1.00 91.68  ? 576 GLN B C   1 
ATOM   6252 O O   . GLN B 1 576 ? 172.147 219.059 183.728 1.00 91.54  ? 576 GLN B O   1 
ATOM   6253 C CB  . GLN B 1 576 ? 174.705 219.535 185.811 1.00 89.01  ? 576 GLN B CB  1 
ATOM   6254 C CG  . GLN B 1 576 ? 174.767 218.043 185.508 1.00 89.60  ? 576 GLN B CG  1 
ATOM   6255 C CD  . GLN B 1 576 ? 173.792 217.233 186.340 1.00 92.44  ? 576 GLN B CD  1 
ATOM   6256 O OE1 . GLN B 1 576 ? 173.922 217.151 187.561 1.00 91.14  ? 576 GLN B OE1 1 
ATOM   6257 N NE2 . GLN B 1 576 ? 172.810 216.627 185.682 1.00 88.74  ? 576 GLN B NE2 1 
ATOM   6258 N N   . ILE B 1 577 ? 171.571 219.951 185.722 1.00 90.99  ? 577 ILE B N   1 
ATOM   6259 C CA  . ILE B 1 577 ? 170.189 219.486 185.624 1.00 89.82  ? 577 ILE B CA  1 
ATOM   6260 C C   . ILE B 1 577 ? 169.540 220.031 184.362 1.00 92.92  ? 577 ILE B C   1 
ATOM   6261 O O   . ILE B 1 577 ? 168.959 219.285 183.561 1.00 91.77  ? 577 ILE B O   1 
ATOM   6262 C CB  . ILE B 1 577 ? 169.392 219.902 186.873 1.00 90.86  ? 577 ILE B CB  1 
ATOM   6263 C CG1 . ILE B 1 577 ? 170.024 219.334 188.139 1.00 87.58  ? 577 ILE B CG1 1 
ATOM   6264 C CG2 . ILE B 1 577 ? 167.928 219.516 186.741 1.00 91.92  ? 577 ILE B CG2 1 
ATOM   6265 C CD1 . ILE B 1 577 ? 169.536 220.012 189.384 1.00 87.87  ? 577 ILE B CD1 1 
ATOM   6266 N N   . SER B 1 578 ? 169.655 221.343 184.157 1.00 101.72 ? 578 SER B N   1 
ATOM   6267 C CA  . SER B 1 578 ? 168.993 221.968 183.019 1.00 102.77 ? 578 SER B CA  1 
ATOM   6268 C C   . SER B 1 578 ? 169.527 221.423 181.697 1.00 102.42 ? 578 SER B C   1 
ATOM   6269 O O   . SER B 1 578 ? 168.751 221.018 180.823 1.00 100.73 ? 578 SER B O   1 
ATOM   6270 C CB  . SER B 1 578 ? 169.166 223.478 183.093 1.00 104.17 ? 578 SER B CB  1 
ATOM   6271 O OG  . SER B 1 578 ? 170.534 223.831 183.127 1.00 105.17 ? 578 SER B OG  1 
ATOM   6272 N N   . ILE B 1 579 ? 170.855 221.383 181.541 1.00 96.46  ? 579 ILE B N   1 
ATOM   6273 C CA  . ILE B 1 579 ? 171.446 220.991 180.263 1.00 94.26  ? 579 ILE B CA  1 
ATOM   6274 C C   . ILE B 1 579 ? 171.157 219.532 179.951 1.00 94.90  ? 579 ILE B C   1 
ATOM   6275 O O   . ILE B 1 579 ? 170.897 219.182 178.792 1.00 95.35  ? 579 ILE B O   1 
ATOM   6276 C CB  . ILE B 1 579 ? 172.962 221.285 180.239 1.00 94.27  ? 579 ILE B CB  1 
ATOM   6277 C CG1 . ILE B 1 579 ? 173.694 220.487 181.320 1.00 96.25  ? 579 ILE B CG1 1 
ATOM   6278 C CG2 . ILE B 1 579 ? 173.223 222.786 180.340 1.00 94.81  ? 579 ILE B CG2 1 
ATOM   6279 C CD1 . ILE B 1 579 ? 175.108 220.939 181.574 1.00 95.25  ? 579 ILE B CD1 1 
ATOM   6280 N N   . THR B 1 580 ? 171.187 218.654 180.956 1.00 104.61 ? 580 THR B N   1 
ATOM   6281 C CA  . THR B 1 580 ? 170.820 217.277 180.672 1.00 105.23 ? 580 THR B CA  1 
ATOM   6282 C C   . THR B 1 580 ? 169.319 217.127 180.452 1.00 104.32 ? 580 THR B C   1 
ATOM   6283 O O   . THR B 1 580 ? 168.895 216.160 179.810 1.00 103.57 ? 580 THR B O   1 
ATOM   6284 C CB  . THR B 1 580 ? 171.301 216.353 181.795 1.00 108.56 ? 580 THR B CB  1 
ATOM   6285 O OG1 . THR B 1 580 ? 172.690 216.600 182.043 1.00 106.55 ? 580 THR B OG1 1 
ATOM   6286 C CG2 . THR B 1 580 ? 171.178 214.910 181.358 1.00 106.05 ? 580 THR B CG2 1 
ATOM   6287 N N   . SER B 1 581 ? 168.510 218.068 180.931 1.00 100.51 ? 581 SER B N   1 
ATOM   6288 C CA  . SER B 1 581 ? 167.087 218.109 180.589 1.00 100.92 ? 581 SER B CA  1 
ATOM   6289 C C   . SER B 1 581 ? 166.872 218.680 179.190 1.00 104.05 ? 581 SER B C   1 
ATOM   6290 O O   . SER B 1 581 ? 166.200 219.696 179.010 1.00 101.20 ? 581 SER B O   1 
ATOM   6291 C CB  . SER B 1 581 ? 166.322 218.913 181.633 1.00 98.87  ? 581 SER B CB  1 
ATOM   6292 O OG  . SER B 1 581 ? 166.436 218.313 182.912 1.00 94.61  ? 581 SER B OG  1 
ATOM   6293 N N   . THR B 1 582 ? 167.447 217.995 178.193 1.00 116.08 ? 582 THR B N   1 
ATOM   6294 C CA  . THR B 1 582 ? 167.380 218.336 176.760 1.00 113.13 ? 582 THR B CA  1 
ATOM   6295 C C   . THR B 1 582 ? 167.400 219.845 176.507 1.00 112.41 ? 582 THR B C   1 
ATOM   6296 O O   . THR B 1 582 ? 166.585 220.385 175.758 1.00 109.76 ? 582 THR B O   1 
ATOM   6297 C CB  . THR B 1 582 ? 166.170 217.686 176.067 1.00 112.47 ? 582 THR B CB  1 
ATOM   6298 O OG1 . THR B 1 582 ? 165.973 218.292 174.784 1.00 113.92 ? 582 THR B OG1 1 
ATOM   6299 C CG2 . THR B 1 582 ? 164.884 217.819 176.878 1.00 111.19 ? 582 THR B CG2 1 
ATOM   6300 N N   . THR B 1 583 ? 168.369 220.528 177.115 1.00 113.37 ? 583 THR B N   1 
ATOM   6301 C CA  . THR B 1 583 ? 168.517 221.964 176.896 1.00 111.74 ? 583 THR B CA  1 
ATOM   6302 C C   . THR B 1 583 ? 169.533 222.279 175.803 1.00 108.68 ? 583 THR B C   1 
ATOM   6303 O O   . THR B 1 583 ? 169.226 223.016 174.861 1.00 107.12 ? 583 THR B O   1 
ATOM   6304 C CB  . THR B 1 583 ? 168.917 222.663 178.197 1.00 112.84 ? 583 THR B CB  1 
ATOM   6305 O OG1 . THR B 1 583 ? 167.969 222.344 179.223 1.00 111.51 ? 583 THR B OG1 1 
ATOM   6306 C CG2 . THR B 1 583 ? 168.966 224.169 178.002 1.00 111.46 ? 583 THR B CG2 1 
ATOM   6307 N N   . LEU B 1 584 ? 170.741 221.735 175.915 1.00 113.70 ? 584 LEU B N   1 
ATOM   6308 C CA  . LEU B 1 584 ? 171.805 221.967 174.948 1.00 115.17 ? 584 LEU B CA  1 
ATOM   6309 C C   . LEU B 1 584 ? 171.973 220.713 174.102 1.00 118.03 ? 584 LEU B C   1 
ATOM   6310 O O   . LEU B 1 584 ? 172.640 219.761 174.521 1.00 116.94 ? 584 LEU B O   1 
ATOM   6311 C CB  . LEU B 1 584 ? 173.113 222.331 175.647 1.00 117.38 ? 584 LEU B CB  1 
ATOM   6312 C CG  . LEU B 1 584 ? 173.585 223.766 175.414 1.00 116.55 ? 584 LEU B CG  1 
ATOM   6313 C CD1 . LEU B 1 584 ? 174.899 224.031 176.130 1.00 115.66 ? 584 LEU B CD1 1 
ATOM   6314 C CD2 . LEU B 1 584 ? 173.712 224.051 173.927 1.00 115.88 ? 584 LEU B CD2 1 
ATOM   6315 N N   . LEU B 1 585 ? 171.363 220.715 172.919 1.00 129.51 ? 585 LEU B N   1 
ATOM   6316 C CA  . LEU B 1 585 ? 171.383 219.564 172.022 1.00 130.07 ? 585 LEU B CA  1 
ATOM   6317 C C   . LEU B 1 585 ? 172.752 219.255 171.404 1.00 131.22 ? 585 LEU B C   1 
ATOM   6318 O O   . LEU B 1 585 ? 173.048 218.072 171.191 1.00 132.00 ? 585 LEU B O   1 
ATOM   6319 C CB  . LEU B 1 585 ? 170.325 219.740 170.922 1.00 129.06 ? 585 LEU B CB  1 
ATOM   6320 C CG  . LEU B 1 585 ? 170.303 220.950 169.980 1.00 128.58 ? 585 LEU B CG  1 
ATOM   6321 C CD1 . LEU B 1 585 ? 171.013 220.636 168.668 1.00 130.19 ? 585 LEU B CD1 1 
ATOM   6322 C CD2 . LEU B 1 585 ? 168.889 221.449 169.732 1.00 127.75 ? 585 LEU B CD2 1 
ATOM   6323 N N   . PRO B 1 586 ? 173.619 220.233 171.097 1.00 130.17 ? 586 PRO B N   1 
ATOM   6324 C CA  . PRO B 1 586 ? 174.931 219.871 170.535 1.00 127.95 ? 586 PRO B CA  1 
ATOM   6325 C C   . PRO B 1 586 ? 175.759 219.066 171.525 1.00 127.63 ? 586 PRO B C   1 
ATOM   6326 O O   . PRO B 1 586 ? 175.476 219.002 172.723 1.00 126.74 ? 586 PRO B O   1 
ATOM   6327 C CB  . PRO B 1 586 ? 175.603 221.210 170.211 1.00 127.67 ? 586 PRO B CB  1 
ATOM   6328 C CG  . PRO B 1 586 ? 174.637 222.255 170.487 1.00 128.98 ? 586 PRO B CG  1 
ATOM   6329 C CD  . PRO B 1 586 ? 173.411 221.696 171.103 1.00 128.39 ? 586 PRO B CD  1 
ATOM   6330 N N   . HIS B 1 587 ? 176.817 218.447 170.995 1.00 119.14 ? 587 HIS B N   1 
ATOM   6331 C CA  . HIS B 1 587 ? 177.641 217.540 171.785 1.00 119.61 ? 587 HIS B CA  1 
ATOM   6332 C C   . HIS B 1 587 ? 178.316 218.230 172.963 1.00 119.92 ? 587 HIS B C   1 
ATOM   6333 O O   . HIS B 1 587 ? 178.749 217.546 173.898 1.00 118.35 ? 587 HIS B O   1 
ATOM   6334 C CB  . HIS B 1 587 ? 178.699 216.884 170.895 1.00 117.64 ? 587 HIS B CB  1 
ATOM   6335 C CG  . HIS B 1 587 ? 178.141 215.883 169.933 1.00 117.73 ? 587 HIS B CG  1 
ATOM   6336 N ND1 . HIS B 1 587 ? 178.315 215.982 168.570 1.00 120.20 ? 587 HIS B ND1 1 
ATOM   6337 C CD2 . HIS B 1 587 ? 177.395 214.772 170.137 1.00 118.27 ? 587 HIS B CD2 1 
ATOM   6338 C CE1 . HIS B 1 587 ? 177.712 214.968 167.977 1.00 120.41 ? 587 HIS B CE1 1 
ATOM   6339 N NE2 . HIS B 1 587 ? 177.145 214.219 168.905 1.00 121.35 ? 587 HIS B NE2 1 
ATOM   6340 N N   . SER B 1 588 ? 178.424 219.562 172.942 1.00 109.68 ? 588 SER B N   1 
ATOM   6341 C CA  . SER B 1 588 ? 179.020 220.268 174.073 1.00 108.14 ? 588 SER B CA  1 
ATOM   6342 C C   . SER B 1 588 ? 178.205 220.062 175.344 1.00 107.79 ? 588 SER B C   1 
ATOM   6343 O O   . SER B 1 588 ? 178.760 220.035 176.449 1.00 107.65 ? 588 SER B O   1 
ATOM   6344 C CB  . SER B 1 588 ? 179.150 221.756 173.755 1.00 108.28 ? 588 SER B CB  1 
ATOM   6345 O OG  . SER B 1 588 ? 179.724 222.462 174.842 1.00 109.59 ? 588 SER B OG  1 
ATOM   6346 N N   . GLY B 1 589 ? 176.885 219.917 175.206 1.00 95.39  ? 589 GLY B N   1 
ATOM   6347 C CA  . GLY B 1 589 ? 176.052 219.683 176.375 1.00 96.33  ? 589 GLY B CA  1 
ATOM   6348 C C   . GLY B 1 589 ? 176.385 218.380 177.074 1.00 98.11  ? 589 GLY B C   1 
ATOM   6349 O O   . GLY B 1 589 ? 176.485 218.325 178.302 1.00 98.47  ? 589 GLY B O   1 
ATOM   6350 N N   . ASP B 1 590 ? 176.569 217.310 176.298 1.00 90.97  ? 590 ASP B N   1 
ATOM   6351 C CA  . ASP B 1 590 ? 176.932 216.026 176.887 1.00 89.39  ? 590 ASP B CA  1 
ATOM   6352 C C   . ASP B 1 590 ? 178.311 216.090 177.534 1.00 85.95  ? 590 ASP B C   1 
ATOM   6353 O O   . ASP B 1 590 ? 178.518 215.550 178.627 1.00 88.49  ? 590 ASP B O   1 
ATOM   6354 C CB  . ASP B 1 590 ? 176.877 214.929 175.824 1.00 89.24  ? 590 ASP B CB  1 
ATOM   6355 C CG  . ASP B 1 590 ? 175.501 214.306 175.702 1.00 92.13  ? 590 ASP B CG  1 
ATOM   6356 O OD1 . ASP B 1 590 ? 174.500 215.044 175.814 1.00 90.06  ? 590 ASP B OD1 1 
ATOM   6357 O OD2 . ASP B 1 590 ? 175.421 213.077 175.494 1.00 94.38  ? 590 ASP B OD2 1 
ATOM   6358 N N   . ILE B 1 591 ? 179.263 216.759 176.877 1.00 76.72  ? 591 ILE B N   1 
ATOM   6359 C CA  . ILE B 1 591 ? 180.597 216.935 177.452 1.00 76.85  ? 591 ILE B CA  1 
ATOM   6360 C C   . ILE B 1 591 ? 180.506 217.631 178.804 1.00 78.68  ? 591 ILE B C   1 
ATOM   6361 O O   . ILE B 1 591 ? 181.054 217.158 179.808 1.00 80.27  ? 591 ILE B O   1 
ATOM   6362 C CB  . ILE B 1 591 ? 181.497 217.727 176.485 1.00 77.75  ? 591 ILE B CB  1 
ATOM   6363 C CG1 . ILE B 1 591 ? 181.934 216.868 175.298 1.00 81.22  ? 591 ILE B CG1 1 
ATOM   6364 C CG2 . ILE B 1 591 ? 182.716 218.273 177.216 1.00 76.74  ? 591 ILE B CG2 1 
ATOM   6365 C CD1 . ILE B 1 591 ? 182.660 215.612 175.703 1.00 83.44  ? 591 ILE B CD1 1 
ATOM   6366 N N   . ILE B 1 592 ? 179.797 218.759 178.851 1.00 82.76  ? 592 ILE B N   1 
ATOM   6367 C CA  . ILE B 1 592 ? 179.775 219.557 180.071 1.00 85.24  ? 592 ILE B CA  1 
ATOM   6368 C C   . ILE B 1 592 ? 178.970 218.865 181.168 1.00 83.69  ? 592 ILE B C   1 
ATOM   6369 O O   . ILE B 1 592 ? 179.298 218.991 182.353 1.00 83.59  ? 592 ILE B O   1 
ATOM   6370 C CB  . ILE B 1 592 ? 179.265 220.979 179.762 1.00 84.86  ? 592 ILE B CB  1 
ATOM   6371 C CG1 . ILE B 1 592 ? 179.559 221.924 180.929 1.00 82.16  ? 592 ILE B CG1 1 
ATOM   6372 C CG2 . ILE B 1 592 ? 177.798 220.976 179.388 1.00 81.94  ? 592 ILE B CG2 1 
ATOM   6373 C CD1 . ILE B 1 592 ? 181.021 221.979 181.314 1.00 81.33  ? 592 ILE B CD1 1 
ATOM   6374 N N   . ALA B 1 593 ? 177.933 218.102 180.808 1.00 74.93  ? 593 ALA B N   1 
ATOM   6375 C CA  . ALA B 1 593 ? 177.196 217.350 181.820 1.00 73.10  ? 593 ALA B CA  1 
ATOM   6376 C C   . ALA B 1 593 ? 178.039 216.217 182.395 1.00 76.88  ? 593 ALA B C   1 
ATOM   6377 O O   . ALA B 1 593 ? 178.052 216.000 183.617 1.00 81.90  ? 593 ALA B O   1 
ATOM   6378 C CB  . ALA B 1 593 ? 175.897 216.805 181.227 1.00 68.85  ? 593 ALA B CB  1 
ATOM   6379 N N   . THR B 1 594 ? 178.740 215.476 181.530 1.00 67.56  ? 594 THR B N   1 
ATOM   6380 C CA  . THR B 1 594 ? 179.609 214.404 182.000 1.00 60.05  ? 594 THR B CA  1 
ATOM   6381 C C   . THR B 1 594 ? 180.765 214.950 182.826 1.00 59.93  ? 594 THR B C   1 
ATOM   6382 O O   . THR B 1 594 ? 181.296 214.243 183.688 1.00 63.96  ? 594 THR B O   1 
ATOM   6383 C CB  . THR B 1 594 ? 180.133 213.598 180.810 1.00 62.73  ? 594 THR B CB  1 
ATOM   6384 O OG1 . THR B 1 594 ? 179.047 213.283 179.931 1.00 67.82  ? 594 THR B OG1 1 
ATOM   6385 C CG2 . THR B 1 594 ? 180.776 212.301 181.279 1.00 65.87  ? 594 THR B CG2 1 
ATOM   6386 N N   . VAL B 1 595 ? 181.176 216.194 182.572 1.00 59.90  ? 595 VAL B N   1 
ATOM   6387 C CA  . VAL B 1 595 ? 182.174 216.849 183.413 1.00 62.88  ? 595 VAL B CA  1 
ATOM   6388 C C   . VAL B 1 595 ? 181.608 217.304 184.754 1.00 69.54  ? 595 VAL B C   1 
ATOM   6389 O O   . VAL B 1 595 ? 182.262 217.098 185.790 1.00 71.22  ? 595 VAL B O   1 
ATOM   6390 C CB  . VAL B 1 595 ? 182.817 218.047 182.679 1.00 65.27  ? 595 VAL B CB  1 
ATOM   6391 C CG1 . VAL B 1 595 ? 183.602 218.918 183.648 1.00 69.63  ? 595 VAL B CG1 1 
ATOM   6392 C CG2 . VAL B 1 595 ? 183.717 217.556 181.559 1.00 68.20  ? 595 VAL B CG2 1 
ATOM   6393 N N   . PHE B 1 596 ? 180.409 217.889 184.777 1.00 76.75  ? 596 PHE B N   1 
ATOM   6394 C CA  . PHE B 1 596 ? 179.842 218.441 186.000 1.00 70.71  ? 596 PHE B CA  1 
ATOM   6395 C C   . PHE B 1 596 ? 179.289 217.395 186.959 1.00 71.35  ? 596 PHE B C   1 
ATOM   6396 O O   . PHE B 1 596 ? 179.245 217.659 188.165 1.00 72.16  ? 596 PHE B O   1 
ATOM   6397 C CB  . PHE B 1 596 ? 178.727 219.442 185.673 1.00 68.19  ? 596 PHE B CB  1 
ATOM   6398 C CG  . PHE B 1 596 ? 179.218 220.840 185.433 1.00 73.90  ? 596 PHE B CG  1 
ATOM   6399 C CD1 . PHE B 1 596 ? 180.234 221.372 186.208 1.00 74.05  ? 596 PHE B CD1 1 
ATOM   6400 C CD2 . PHE B 1 596 ? 178.668 221.621 184.432 1.00 77.89  ? 596 PHE B CD2 1 
ATOM   6401 C CE1 . PHE B 1 596 ? 180.691 222.657 185.993 1.00 74.98  ? 596 PHE B CE1 1 
ATOM   6402 C CE2 . PHE B 1 596 ? 179.118 222.909 184.214 1.00 80.17  ? 596 PHE B CE2 1 
ATOM   6403 C CZ  . PHE B 1 596 ? 180.132 223.426 184.994 1.00 80.35  ? 596 PHE B CZ  1 
ATOM   6404 N N   . ALA B 1 597 ? 178.852 216.229 186.465 1.00 60.22  ? 597 ALA B N   1 
ATOM   6405 C CA  . ALA B 1 597 ? 178.297 215.229 187.378 1.00 61.68  ? 597 ALA B CA  1 
ATOM   6406 C C   . ALA B 1 597 ? 179.303 214.778 188.436 1.00 62.81  ? 597 ALA B C   1 
ATOM   6407 O O   . ALA B 1 597 ? 178.933 214.717 189.624 1.00 58.35  ? 597 ALA B O   1 
ATOM   6408 C CB  . ALA B 1 597 ? 177.733 214.049 186.580 1.00 53.81  ? 597 ALA B CB  1 
ATOM   6409 N N   . PRO B 1 598 ? 180.559 214.443 188.100 1.00 53.69  ? 598 PRO B N   1 
ATOM   6410 C CA  . PRO B 1 598 ? 181.534 214.171 189.170 1.00 50.53  ? 598 PRO B CA  1 
ATOM   6411 C C   . PRO B 1 598 ? 181.726 215.344 190.112 1.00 59.95  ? 598 PRO B C   1 
ATOM   6412 O O   . PRO B 1 598 ? 181.915 215.143 191.319 1.00 66.87  ? 598 PRO B O   1 
ATOM   6413 C CB  . PRO B 1 598 ? 182.817 213.847 188.393 1.00 55.16  ? 598 PRO B CB  1 
ATOM   6414 C CG  . PRO B 1 598 ? 182.342 213.344 187.088 1.00 60.30  ? 598 PRO B CG  1 
ATOM   6415 C CD  . PRO B 1 598 ? 181.133 214.166 186.772 1.00 57.13  ? 598 PRO B CD  1 
ATOM   6416 N N   . LEU B 1 599 ? 181.682 216.571 189.591 1.00 59.40  ? 599 LEU B N   1 
ATOM   6417 C CA  . LEU B 1 599 ? 181.736 217.741 190.459 1.00 61.05  ? 599 LEU B CA  1 
ATOM   6418 C C   . LEU B 1 599 ? 180.531 217.794 191.387 1.00 58.45  ? 599 LEU B C   1 
ATOM   6419 O O   . LEU B 1 599 ? 180.657 218.196 192.548 1.00 61.58  ? 599 LEU B O   1 
ATOM   6420 C CB  . LEU B 1 599 ? 181.823 219.016 189.621 1.00 64.51  ? 599 LEU B CB  1 
ATOM   6421 C CG  . LEU B 1 599 ? 183.220 219.595 189.387 1.00 65.77  ? 599 LEU B CG  1 
ATOM   6422 C CD1 . LEU B 1 599 ? 183.870 219.978 190.706 1.00 61.56  ? 599 LEU B CD1 1 
ATOM   6423 C CD2 . LEU B 1 599 ? 184.094 218.620 188.616 1.00 66.54  ? 599 LEU B CD2 1 
ATOM   6424 N N   . GLU B 1 600 ? 179.358 217.390 190.894 1.00 56.17  ? 600 GLU B N   1 
ATOM   6425 C CA  . GLU B 1 600 ? 178.174 217.326 191.744 1.00 57.83  ? 600 GLU B CA  1 
ATOM   6426 C C   . GLU B 1 600 ? 178.360 216.323 192.876 1.00 65.01  ? 600 GLU B C   1 
ATOM   6427 O O   . GLU B 1 600 ? 178.012 216.604 194.031 1.00 68.24  ? 600 GLU B O   1 
ATOM   6428 C CB  . GLU B 1 600 ? 176.954 216.964 190.900 1.00 62.75  ? 600 GLU B CB  1 
ATOM   6429 C CG  . GLU B 1 600 ? 175.734 216.553 191.698 1.00 67.17  ? 600 GLU B CG  1 
ATOM   6430 C CD  . GLU B 1 600 ? 174.679 215.893 190.833 1.00 71.91  ? 600 GLU B CD  1 
ATOM   6431 O OE1 . GLU B 1 600 ? 174.981 215.582 189.662 1.00 73.85  ? 600 GLU B OE1 1 
ATOM   6432 O OE2 . GLU B 1 600 ? 173.545 215.700 191.315 1.00 73.07  ? 600 GLU B OE2 1 
ATOM   6433 N N   . VAL B 1 601 ? 178.916 215.149 192.568 1.00 54.16  ? 601 VAL B N   1 
ATOM   6434 C CA  . VAL B 1 601 ? 179.140 214.152 193.613 1.00 42.19  ? 601 VAL B CA  1 
ATOM   6435 C C   . VAL B 1 601 ? 180.177 214.649 194.617 1.00 39.39  ? 601 VAL B C   1 
ATOM   6436 O O   . VAL B 1 601 ? 180.048 214.427 195.828 1.00 51.42  ? 601 VAL B O   1 
ATOM   6437 C CB  . VAL B 1 601 ? 179.548 212.806 192.991 1.00 38.45  ? 601 VAL B CB  1 
ATOM   6438 C CG1 . VAL B 1 601 ? 179.702 211.751 194.070 1.00 36.21  ? 601 VAL B CG1 1 
ATOM   6439 C CG2 . VAL B 1 601 ? 178.517 212.370 191.967 1.00 48.16  ? 601 VAL B CG2 1 
ATOM   6440 N N   . PHE B 1 602 ? 181.219 215.327 194.132 1.00 34.06  ? 602 PHE B N   1 
ATOM   6441 C CA  . PHE B 1 602 ? 182.227 215.891 195.025 1.00 36.74  ? 602 PHE B CA  1 
ATOM   6442 C C   . PHE B 1 602 ? 181.620 216.943 195.949 1.00 48.88  ? 602 PHE B C   1 
ATOM   6443 O O   . PHE B 1 602 ? 181.938 216.993 197.147 1.00 51.96  ? 602 PHE B O   1 
ATOM   6444 C CB  . PHE B 1 602 ? 183.367 216.482 194.196 1.00 37.18  ? 602 PHE B CB  1 
ATOM   6445 C CG  . PHE B 1 602 ? 184.379 217.240 195.000 1.00 43.49  ? 602 PHE B CG  1 
ATOM   6446 C CD1 . PHE B 1 602 ? 185.201 216.585 195.900 1.00 53.24  ? 602 PHE B CD1 1 
ATOM   6447 C CD2 . PHE B 1 602 ? 184.523 218.607 194.842 1.00 43.33  ? 602 PHE B CD2 1 
ATOM   6448 C CE1 . PHE B 1 602 ? 186.138 217.281 196.637 1.00 56.79  ? 602 PHE B CE1 1 
ATOM   6449 C CE2 . PHE B 1 602 ? 185.458 219.308 195.575 1.00 45.27  ? 602 PHE B CE2 1 
ATOM   6450 C CZ  . PHE B 1 602 ? 186.266 218.645 196.474 1.00 55.81  ? 602 PHE B CZ  1 
ATOM   6451 N N   . ARG B 1 603 ? 180.745 217.794 195.408 1.00 50.74  ? 603 ARG B N   1 
ATOM   6452 C CA  . ARG B 1 603 ? 180.067 218.785 196.235 1.00 49.21  ? 603 ARG B CA  1 
ATOM   6453 C C   . ARG B 1 603 ? 179.172 218.121 197.270 1.00 44.06  ? 603 ARG B C   1 
ATOM   6454 O O   . ARG B 1 603 ? 179.088 218.580 198.412 1.00 55.22  ? 603 ARG B O   1 
ATOM   6455 C CB  . ARG B 1 603 ? 179.251 219.739 195.366 1.00 51.54  ? 603 ARG B CB  1 
ATOM   6456 C CG  . ARG B 1 603 ? 178.735 220.948 196.125 1.00 48.25  ? 603 ARG B CG  1 
ATOM   6457 C CD  . ARG B 1 603 ? 177.324 221.289 195.694 1.00 52.28  ? 603 ARG B CD  1 
ATOM   6458 N NE  . ARG B 1 603 ? 176.342 220.475 196.399 1.00 46.85  ? 603 ARG B NE  1 
ATOM   6459 C CZ  . ARG B 1 603 ? 175.496 219.646 195.805 1.00 52.26  ? 603 ARG B CZ  1 
ATOM   6460 N NH1 . ARG B 1 603 ? 175.485 219.494 194.491 1.00 50.70  ? 603 ARG B NH1 1 
ATOM   6461 N NH2 . ARG B 1 603 ? 174.643 218.948 196.548 1.00 57.05  ? 603 ARG B NH2 1 
ATOM   6462 N N   . ARG B 1 604 ? 178.482 217.046 196.888 1.00 28.39  ? 604 ARG B N   1 
ATOM   6463 C CA  . ARG B 1 604 ? 177.670 216.330 197.865 1.00 30.33  ? 604 ARG B CA  1 
ATOM   6464 C C   . ARG B 1 604 ? 178.526 215.728 198.973 1.00 35.25  ? 604 ARG B C   1 
ATOM   6465 O O   . ARG B 1 604 ? 178.127 215.741 200.140 1.00 40.60  ? 604 ARG B O   1 
ATOM   6466 C CB  . ARG B 1 604 ? 176.845 215.246 197.177 1.00 32.81  ? 604 ARG B CB  1 
ATOM   6467 C CG  . ARG B 1 604 ? 176.101 214.343 198.139 1.00 33.80  ? 604 ARG B CG  1 
ATOM   6468 C CD  . ARG B 1 604 ? 175.128 215.118 199.020 1.00 27.36  ? 604 ARG B CD  1 
ATOM   6469 N NE  . ARG B 1 604 ? 174.246 215.984 198.249 1.00 37.37  ? 604 ARG B NE  1 
ATOM   6470 C CZ  . ARG B 1 604 ? 173.304 216.756 198.773 1.00 42.38  ? 604 ARG B CZ  1 
ATOM   6471 N NH1 . ARG B 1 604 ? 173.107 216.814 200.078 1.00 26.36  ? 604 ARG B NH1 1 
ATOM   6472 N NH2 . ARG B 1 604 ? 172.539 217.485 197.967 1.00 48.73  ? 604 ARG B NH2 1 
ATOM   6473 N N   . PHE B 1 605 ? 179.700 215.202 198.628 1.00 39.83  ? 605 PHE B N   1 
ATOM   6474 C CA  . PHE B 1 605 ? 180.614 214.657 199.631 1.00 37.59  ? 605 PHE B CA  1 
ATOM   6475 C C   . PHE B 1 605 ? 181.082 215.738 200.607 1.00 44.43  ? 605 PHE B C   1 
ATOM   6476 O O   . PHE B 1 605 ? 181.060 215.546 201.837 1.00 54.11  ? 605 PHE B O   1 
ATOM   6477 C CB  . PHE B 1 605 ? 181.788 213.993 198.905 1.00 38.25  ? 605 PHE B CB  1 
ATOM   6478 C CG  . PHE B 1 605 ? 183.121 214.179 199.567 1.00 42.94  ? 605 PHE B CG  1 
ATOM   6479 C CD1 . PHE B 1 605 ? 183.505 213.378 200.624 1.00 40.14  ? 605 PHE B CD1 1 
ATOM   6480 C CD2 . PHE B 1 605 ? 184.006 215.140 199.105 1.00 48.08  ? 605 PHE B CD2 1 
ATOM   6481 C CE1 . PHE B 1 605 ? 184.740 213.541 201.219 1.00 44.00  ? 605 PHE B CE1 1 
ATOM   6482 C CE2 . PHE B 1 605 ? 185.240 215.310 199.699 1.00 40.66  ? 605 PHE B CE2 1 
ATOM   6483 C CZ  . PHE B 1 605 ? 185.607 214.510 200.757 1.00 38.96  ? 605 PHE B CZ  1 
ATOM   6484 N N   . VAL B 1 606 ? 181.495 216.892 200.076 1.00 37.58  ? 606 VAL B N   1 
ATOM   6485 C CA  . VAL B 1 606 ? 181.953 217.964 200.954 1.00 43.85  ? 606 VAL B CA  1 
ATOM   6486 C C   . VAL B 1 606 ? 180.795 218.525 201.773 1.00 42.79  ? 606 VAL B C   1 
ATOM   6487 O O   . VAL B 1 606 ? 180.994 218.991 202.901 1.00 42.15  ? 606 VAL B O   1 
ATOM   6488 C CB  . VAL B 1 606 ? 182.676 219.062 200.149 1.00 41.02  ? 606 VAL B CB  1 
ATOM   6489 C CG1 . VAL B 1 606 ? 181.687 219.936 199.417 1.00 46.74  ? 606 VAL B CG1 1 
ATOM   6490 C CG2 . VAL B 1 606 ? 183.547 219.900 201.067 1.00 43.26  ? 606 VAL B CG2 1 
ATOM   6491 N N   . TRP B 1 607 ? 179.573 218.492 201.234 1.00 45.38  ? 607 TRP B N   1 
ATOM   6492 C CA  . TRP B 1 607 ? 178.408 218.896 202.013 1.00 37.02  ? 607 TRP B CA  1 
ATOM   6493 C C   . TRP B 1 607 ? 178.139 217.905 203.134 1.00 31.87  ? 607 TRP B C   1 
ATOM   6494 O O   . TRP B 1 607 ? 177.744 218.300 204.236 1.00 50.40  ? 607 TRP B O   1 
ATOM   6495 C CB  . TRP B 1 607 ? 177.184 219.021 201.104 1.00 43.98  ? 607 TRP B CB  1 
ATOM   6496 C CG  . TRP B 1 607 ? 175.872 219.120 201.836 1.00 40.67  ? 607 TRP B CG  1 
ATOM   6497 C CD1 . TRP B 1 607 ? 175.201 220.263 202.155 1.00 44.37  ? 607 TRP B CD1 1 
ATOM   6498 C CD2 . TRP B 1 607 ? 175.069 218.036 202.327 1.00 40.76  ? 607 TRP B CD2 1 
ATOM   6499 N NE1 . TRP B 1 607 ? 174.037 219.962 202.818 1.00 45.02  ? 607 TRP B NE1 1 
ATOM   6500 C CE2 . TRP B 1 607 ? 173.933 218.602 202.937 1.00 40.37  ? 607 TRP B CE2 1 
ATOM   6501 C CE3 . TRP B 1 607 ? 175.203 216.645 202.315 1.00 43.92  ? 607 TRP B CE3 1 
ATOM   6502 C CZ2 . TRP B 1 607 ? 172.939 217.826 203.526 1.00 46.77  ? 607 TRP B CZ2 1 
ATOM   6503 C CZ3 . TRP B 1 607 ? 174.215 215.877 202.902 1.00 38.76  ? 607 TRP B CZ3 1 
ATOM   6504 C CH2 . TRP B 1 607 ? 173.098 216.469 203.497 1.00 46.29  ? 607 TRP B CH2 1 
ATOM   6505 N N   . ASN B 1 608 ? 178.321 216.613 202.856 1.00 23.41  ? 608 ASN B N   1 
ATOM   6506 C CA  . ASN B 1 608 ? 178.125 215.572 203.855 1.00 34.73  ? 608 ASN B CA  1 
ATOM   6507 C C   . ASN B 1 608 ? 179.059 215.741 205.037 1.00 33.99  ? 608 ASN B C   1 
ATOM   6508 O O   . ASN B 1 608 ? 178.627 215.562 206.185 1.00 39.57  ? 608 ASN B O   1 
ATOM   6509 C CB  . ASN B 1 608 ? 178.341 214.200 203.218 1.00 42.77  ? 608 ASN B CB  1 
ATOM   6510 C CG  . ASN B 1 608 ? 177.133 213.303 203.338 1.00 51.73  ? 608 ASN B CG  1 
ATOM   6511 O OD1 . ASN B 1 608 ? 176.161 213.636 204.015 1.00 52.90  ? 608 ASN B OD1 1 
ATOM   6512 N ND2 . ASN B 1 608 ? 177.181 212.157 202.671 1.00 42.30  ? 608 ASN B ND2 1 
ATOM   6513 N N   . PHE B 1 609 ? 180.326 216.070 204.773 1.00 35.55  ? 609 PHE B N   1 
ATOM   6514 C CA  . PHE B 1 609 ? 181.266 216.383 205.849 1.00 42.73  ? 609 PHE B CA  1 
ATOM   6515 C C   . PHE B 1 609 ? 180.638 217.307 206.890 1.00 55.42  ? 609 PHE B C   1 
ATOM   6516 O O   . PHE B 1 609 ? 180.447 216.930 208.057 1.00 58.20  ? 609 PHE B O   1 
ATOM   6517 C CB  . PHE B 1 609 ? 182.529 217.054 205.299 1.00 37.59  ? 609 PHE B CB  1 
ATOM   6518 C CG  . PHE B 1 609 ? 183.742 216.172 205.297 1.00 40.51  ? 609 PHE B CG  1 
ATOM   6519 C CD1 . PHE B 1 609 ? 184.313 215.761 206.487 1.00 47.40  ? 609 PHE B CD1 1 
ATOM   6520 C CD2 . PHE B 1 609 ? 184.346 215.802 204.111 1.00 40.07  ? 609 PHE B CD2 1 
ATOM   6521 C CE1 . PHE B 1 609 ? 185.435 214.961 206.494 1.00 52.49  ? 609 PHE B CE1 1 
ATOM   6522 C CE2 . PHE B 1 609 ? 185.472 215.004 204.114 1.00 39.91  ? 609 PHE B CE2 1 
ATOM   6523 C CZ  . PHE B 1 609 ? 186.015 214.583 205.306 1.00 47.47  ? 609 PHE B CZ  1 
ATOM   6524 N N   . PHE B 1 610 ? 180.279 218.514 206.452 1.00 48.19  ? 610 PHE B N   1 
ATOM   6525 C CA  . PHE B 1 610 ? 179.839 219.539 207.389 1.00 32.24  ? 610 PHE B CA  1 
ATOM   6526 C C   . PHE B 1 610 ? 178.420 219.294 207.879 1.00 28.63  ? 610 PHE B C   1 
ATOM   6527 O O   . PHE B 1 610 ? 178.088 219.693 208.997 1.00 46.67  ? 610 PHE B O   1 
ATOM   6528 C CB  . PHE B 1 610 ? 179.970 220.919 206.748 1.00 31.50  ? 610 PHE B CB  1 
ATOM   6529 C CG  . PHE B 1 610 ? 181.380 221.269 206.372 1.00 37.37  ? 610 PHE B CG  1 
ATOM   6530 C CD1 . PHE B 1 610 ? 181.897 220.891 205.146 1.00 48.49  ? 610 PHE B CD1 1 
ATOM   6531 C CD2 . PHE B 1 610 ? 182.195 221.956 207.252 1.00 38.83  ? 610 PHE B CD2 1 
ATOM   6532 C CE1 . PHE B 1 610 ? 183.196 221.199 204.801 1.00 45.50  ? 610 PHE B CE1 1 
ATOM   6533 C CE2 . PHE B 1 610 ? 183.496 222.268 206.909 1.00 46.63  ? 610 PHE B CE2 1 
ATOM   6534 C CZ  . PHE B 1 610 ? 183.995 221.891 205.682 1.00 44.74  ? 610 PHE B CZ  1 
ATOM   6535 N N   . ARG B 1 611 ? 177.578 218.629 207.086 1.00 28.75  ? 611 ARG B N   1 
ATOM   6536 C CA  . ARG B 1 611 ? 176.251 218.270 207.575 1.00 20.19  ? 611 ARG B CA  1 
ATOM   6537 C C   . ARG B 1 611 ? 176.353 217.336 208.773 1.00 40.19  ? 611 ARG B C   1 
ATOM   6538 O O   . ARG B 1 611 ? 175.717 217.568 209.807 1.00 54.14  ? 611 ARG B O   1 
ATOM   6539 C CB  . ARG B 1 611 ? 175.429 217.630 206.455 1.00 34.03  ? 611 ARG B CB  1 
ATOM   6540 C CG  . ARG B 1 611 ? 174.064 217.095 206.887 1.00 24.01  ? 611 ARG B CG  1 
ATOM   6541 C CD  . ARG B 1 611 ? 173.306 218.070 207.781 1.00 33.47  ? 611 ARG B CD  1 
ATOM   6542 N NE  . ARG B 1 611 ? 171.935 217.637 208.025 1.00 44.30  ? 611 ARG B NE  1 
ATOM   6543 C CZ  . ARG B 1 611 ? 170.890 218.450 208.088 1.00 52.90  ? 611 ARG B CZ  1 
ATOM   6544 N NH1 . ARG B 1 611 ? 171.017 219.755 207.914 1.00 48.37  ? 611 ARG B NH1 1 
ATOM   6545 N NH2 . ARG B 1 611 ? 169.686 217.942 208.336 1.00 55.66  ? 611 ARG B NH2 1 
ATOM   6546 N N   . LEU B 1 612 ? 177.164 216.280 208.662 1.00 51.28  ? 612 LEU B N   1 
ATOM   6547 C CA  . LEU B 1 612 ? 177.329 215.381 209.799 1.00 36.89  ? 612 LEU B CA  1 
ATOM   6548 C C   . LEU B 1 612 ? 178.011 216.073 210.972 1.00 41.36  ? 612 LEU B C   1 
ATOM   6549 O O   . LEU B 1 612 ? 177.618 215.861 212.130 1.00 49.11  ? 612 LEU B O   1 
ATOM   6550 C CB  . LEU B 1 612 ? 178.111 214.136 209.386 1.00 41.51  ? 612 LEU B CB  1 
ATOM   6551 C CG  . LEU B 1 612 ? 177.247 212.916 209.071 1.00 42.76  ? 612 LEU B CG  1 
ATOM   6552 C CD1 . LEU B 1 612 ? 176.434 212.530 210.295 1.00 32.82  ? 612 LEU B CD1 1 
ATOM   6553 C CD2 . LEU B 1 612 ? 176.340 213.179 207.881 1.00 48.39  ? 612 LEU B CD2 1 
ATOM   6554 N N   . GLU B 1 613 ? 179.022 216.905 210.701 1.00 51.10  ? 613 GLU B N   1 
ATOM   6555 C CA  . GLU B 1 613 ? 179.698 217.594 211.796 1.00 60.24  ? 613 GLU B CA  1 
ATOM   6556 C C   . GLU B 1 613 ? 178.739 218.517 212.544 1.00 55.16  ? 613 GLU B C   1 
ATOM   6557 O O   . GLU B 1 613 ? 178.727 218.537 213.781 1.00 60.82  ? 613 GLU B O   1 
ATOM   6558 C CB  . GLU B 1 613 ? 180.905 218.365 211.263 1.00 54.88  ? 613 GLU B CB  1 
ATOM   6559 C CG  . GLU B 1 613 ? 181.532 219.324 212.260 1.00 57.06  ? 613 GLU B CG  1 
ATOM   6560 C CD  . GLU B 1 613 ? 181.020 220.739 212.112 1.00 58.26  ? 613 GLU B CD  1 
ATOM   6561 O OE1 . GLU B 1 613 ? 180.042 220.944 211.363 1.00 65.61  ? 613 GLU B OE1 1 
ATOM   6562 O OE2 . GLU B 1 613 ? 181.598 221.650 212.740 1.00 62.10  ? 613 GLU B OE2 1 
ATOM   6563 N N   . ASN B 1 614 ? 177.915 219.273 211.815 1.00 43.99  ? 614 ASN B N   1 
ATOM   6564 C CA  . ASN B 1 614 ? 176.912 220.131 212.435 1.00 39.93  ? 614 ASN B CA  1 
ATOM   6565 C C   . ASN B 1 614 ? 175.856 219.329 213.178 1.00 44.19  ? 614 ASN B C   1 
ATOM   6566 O O   . ASN B 1 614 ? 175.397 219.756 214.243 1.00 59.26  ? 614 ASN B O   1 
ATOM   6567 C CB  . ASN B 1 614 ? 176.242 221.009 211.377 1.00 44.70  ? 614 ASN B CB  1 
ATOM   6568 C CG  . ASN B 1 614 ? 174.947 221.627 211.867 1.00 49.58  ? 614 ASN B CG  1 
ATOM   6569 O OD1 . ASN B 1 614 ? 174.957 222.590 212.633 1.00 56.34  ? 614 ASN B OD1 1 
ATOM   6570 N ND2 . ASN B 1 614 ? 173.823 221.072 211.429 1.00 48.88  ? 614 ASN B ND2 1 
ATOM   6571 N N   . GLU B 1 615 ? 175.445 218.184 212.629 1.00 38.42  ? 615 GLU B N   1 
ATOM   6572 C CA  . GLU B 1 615 ? 174.465 217.348 213.310 1.00 43.25  ? 615 GLU B CA  1 
ATOM   6573 C C   . GLU B 1 615 ? 174.995 216.889 214.660 1.00 59.30  ? 615 GLU B C   1 
ATOM   6574 O O   . GLU B 1 615 ? 174.264 216.871 215.657 1.00 61.50  ? 615 GLU B O   1 
ATOM   6575 C CB  . GLU B 1 615 ? 174.107 216.149 212.434 1.00 42.57  ? 615 GLU B CB  1 
ATOM   6576 C CG  . GLU B 1 615 ? 173.041 216.443 211.403 1.00 44.77  ? 615 GLU B CG  1 
ATOM   6577 C CD  . GLU B 1 615 ? 171.764 216.963 212.021 1.00 55.66  ? 615 GLU B CD  1 
ATOM   6578 O OE1 . GLU B 1 615 ? 171.153 216.234 212.829 1.00 59.11  ? 615 GLU B OE1 1 
ATOM   6579 O OE2 . GLU B 1 615 ? 171.372 218.102 211.696 1.00 54.92  ? 615 GLU B OE2 1 
ATOM   6580 N N   . HIS B 1 616 ? 176.272 216.505 214.709 1.00 60.96  ? 616 HIS B N   1 
ATOM   6581 C CA  . HIS B 1 616 ? 176.876 216.154 215.991 1.00 54.97  ? 616 HIS B CA  1 
ATOM   6582 C C   . HIS B 1 616 ? 176.976 217.365 216.910 1.00 57.92  ? 616 HIS B C   1 
ATOM   6583 O O   . HIS B 1 616 ? 176.676 217.272 218.106 1.00 60.25  ? 616 HIS B O   1 
ATOM   6584 C CB  . HIS B 1 616 ? 178.257 215.543 215.780 1.00 50.11  ? 616 HIS B CB  1 
ATOM   6585 C CG  . HIS B 1 616 ? 179.108 215.535 217.011 1.00 58.49  ? 616 HIS B CG  1 
ATOM   6586 N ND1 . HIS B 1 616 ? 180.241 216.310 217.138 1.00 59.62  ? 616 HIS B ND1 1 
ATOM   6587 C CD2 . HIS B 1 616 ? 178.996 214.841 218.168 1.00 62.56  ? 616 HIS B CD2 1 
ATOM   6588 C CE1 . HIS B 1 616 ? 180.788 216.096 218.321 1.00 61.93  ? 616 HIS B CE1 1 
ATOM   6589 N NE2 . HIS B 1 616 ? 180.051 215.209 218.966 1.00 64.30  ? 616 HIS B NE2 1 
ATOM   6590 N N   . LEU B 1 617 ? 177.400 218.509 216.370 1.00 57.79  ? 617 LEU B N   1 
ATOM   6591 C CA  . LEU B 1 617 ? 177.658 219.678 217.205 1.00 59.74  ? 617 LEU B CA  1 
ATOM   6592 C C   . LEU B 1 617 ? 176.373 220.198 217.839 1.00 59.79  ? 617 LEU B C   1 
ATOM   6593 O O   . LEU B 1 617 ? 176.242 220.236 219.068 1.00 61.39  ? 617 LEU B O   1 
ATOM   6594 C CB  . LEU B 1 617 ? 178.336 220.768 216.374 1.00 63.29  ? 617 LEU B CB  1 
ATOM   6595 C CG  . LEU B 1 617 ? 179.858 220.853 216.509 1.00 59.91  ? 617 LEU B CG  1 
ATOM   6596 C CD1 . LEU B 1 617 ? 180.394 222.098 215.820 1.00 62.87  ? 617 LEU B CD1 1 
ATOM   6597 C CD2 . LEU B 1 617 ? 180.275 220.818 217.970 1.00 55.87  ? 617 LEU B CD2 1 
ATOM   6598 N N   . ASN B 1 618 ? 175.410 220.603 217.014 1.00 54.35  ? 618 ASN B N   1 
ATOM   6599 C CA  . ASN B 1 618 ? 174.124 221.093 217.498 1.00 54.10  ? 618 ASN B CA  1 
ATOM   6600 C C   . ASN B 1 618 ? 173.025 220.455 216.666 1.00 50.68  ? 618 ASN B C   1 
ATOM   6601 O O   . ASN B 1 618 ? 173.017 220.596 215.440 1.00 57.49  ? 618 ASN B O   1 
ATOM   6602 C CB  . ASN B 1 618 ? 174.044 222.620 217.419 1.00 51.69  ? 618 ASN B CB  1 
ATOM   6603 C CG  . ASN B 1 618 ? 174.712 223.175 216.179 1.00 52.19  ? 618 ASN B CG  1 
ATOM   6604 O OD1 . ASN B 1 618 ? 175.933 223.321 216.130 1.00 54.54  ? 618 ASN B OD1 1 
ATOM   6605 N ND2 . ASN B 1 618 ? 173.913 223.486 215.166 1.00 48.89  ? 618 ASN B ND2 1 
ATOM   6606 N N   . ASN B 1 619 ? 172.106 219.759 217.331 1.00 48.36  ? 619 ASN B N   1 
ATOM   6607 C CA  . ASN B 1 619 ? 171.047 219.032 216.642 1.00 50.95  ? 619 ASN B CA  1 
ATOM   6608 C C   . ASN B 1 619 ? 170.236 219.962 215.752 1.00 57.48  ? 619 ASN B C   1 
ATOM   6609 O O   . ASN B 1 619 ? 169.575 220.886 216.236 1.00 67.43  ? 619 ASN B O   1 
ATOM   6610 C CB  . ASN B 1 619 ? 170.139 218.347 217.667 1.00 56.41  ? 619 ASN B CB  1 
ATOM   6611 C CG  . ASN B 1 619 ? 169.076 217.474 217.021 1.00 56.45  ? 619 ASN B CG  1 
ATOM   6612 O OD1 . ASN B 1 619 ? 169.067 217.275 215.806 1.00 57.33  ? 619 ASN B OD1 1 
ATOM   6613 N ND2 . ASN B 1 619 ? 168.172 216.947 217.837 1.00 59.06  ? 619 ASN B ND2 1 
ATOM   6614 N N   . CYS B 1 620 ? 170.290 219.710 214.448 1.00 63.61  ? 620 CYS B N   1 
ATOM   6615 C CA  . CYS B 1 620 ? 169.502 220.436 213.464 1.00 67.18  ? 620 CYS B CA  1 
ATOM   6616 C C   . CYS B 1 620 ? 168.494 219.487 212.834 1.00 63.78  ? 620 CYS B C   1 
ATOM   6617 O O   . CYS B 1 620 ? 168.772 218.297 212.659 1.00 58.55  ? 620 CYS B O   1 
ATOM   6618 C CB  . CYS B 1 620 ? 170.394 221.053 212.382 1.00 61.14  ? 620 CYS B CB  1 
ATOM   6619 S SG  . CYS B 1 620 ? 171.412 222.435 212.945 1.00 77.62  ? 620 CYS B SG  1 
ATOM   6620 N N   . GLY B 1 621 ? 167.320 220.013 212.501 1.00 74.28  ? 621 GLY B N   1 
ATOM   6621 C CA  . GLY B 1 621 ? 166.252 219.187 211.986 1.00 70.59  ? 621 GLY B CA  1 
ATOM   6622 C C   . GLY B 1 621 ? 165.527 218.365 213.025 1.00 73.77  ? 621 GLY B C   1 
ATOM   6623 O O   . GLY B 1 621 ? 164.775 217.457 212.651 1.00 75.59  ? 621 GLY B O   1 
ATOM   6624 N N   . GLU B 1 622 ? 165.745 218.645 214.315 1.00 81.86  ? 622 GLU B N   1 
ATOM   6625 C CA  . GLU B 1 622 ? 165.095 217.989 215.449 1.00 84.44  ? 622 GLU B CA  1 
ATOM   6626 C C   . GLU B 1 622 ? 165.027 216.471 215.298 1.00 83.69  ? 622 GLU B C   1 
ATOM   6627 O O   . GLU B 1 622 ? 164.039 215.840 215.689 1.00 85.84  ? 622 GLU B O   1 
ATOM   6628 C CB  . GLU B 1 622 ? 163.698 218.591 215.684 1.00 83.26  ? 622 GLU B CB  1 
ATOM   6629 C CG  . GLU B 1 622 ? 162.628 218.278 214.641 1.00 83.13  ? 622 GLU B CG  1 
ATOM   6630 C CD  . GLU B 1 622 ? 161.554 219.345 214.569 1.00 87.78  ? 622 GLU B CD  1 
ATOM   6631 O OE1 . GLU B 1 622 ? 161.406 220.109 215.545 1.00 87.86  ? 622 GLU B OE1 1 
ATOM   6632 O OE2 . GLU B 1 622 ? 160.858 219.420 213.534 1.00 86.30  ? 622 GLU B OE2 1 
ATOM   6633 N N   . PHE B 1 623 ? 166.092 215.871 214.763 1.00 66.82  ? 623 PHE B N   1 
ATOM   6634 C CA  . PHE B 1 623 ? 166.117 214.422 214.590 1.00 66.59  ? 623 PHE B CA  1 
ATOM   6635 C C   . PHE B 1 623 ? 166.229 213.713 215.934 1.00 67.62  ? 623 PHE B C   1 
ATOM   6636 O O   . PHE B 1 623 ? 165.356 212.922 216.309 1.00 72.92  ? 623 PHE B O   1 
ATOM   6637 C CB  . PHE B 1 623 ? 167.270 214.023 213.666 1.00 63.91  ? 623 PHE B CB  1 
ATOM   6638 C CG  . PHE B 1 623 ? 166.942 214.138 212.205 1.00 61.46  ? 623 PHE B CG  1 
ATOM   6639 C CD1 . PHE B 1 623 ? 165.992 213.313 211.628 1.00 61.51  ? 623 PHE B CD1 1 
ATOM   6640 C CD2 . PHE B 1 623 ? 167.585 215.070 211.409 1.00 63.79  ? 623 PHE B CD2 1 
ATOM   6641 C CE1 . PHE B 1 623 ? 165.687 213.418 210.285 1.00 65.48  ? 623 PHE B CE1 1 
ATOM   6642 C CE2 . PHE B 1 623 ? 167.285 215.178 210.065 1.00 67.68  ? 623 PHE B CE2 1 
ATOM   6643 C CZ  . PHE B 1 623 ? 166.335 214.350 209.503 1.00 69.40  ? 623 PHE B CZ  1 
ATOM   6644 N N   . ARG B 1 624 ? 167.299 213.984 216.675 1.00 70.93  ? 624 ARG B N   1 
ATOM   6645 C CA  . ARG B 1 624 ? 167.475 213.390 217.990 1.00 70.05  ? 624 ARG B CA  1 
ATOM   6646 C C   . ARG B 1 624 ? 166.624 214.117 219.024 1.00 70.02  ? 624 ARG B C   1 
ATOM   6647 O O   . ARG B 1 624 ? 166.266 215.286 218.856 1.00 71.97  ? 624 ARG B O   1 
ATOM   6648 C CB  . ARG B 1 624 ? 168.945 213.424 218.408 1.00 71.10  ? 624 ARG B CB  1 
ATOM   6649 C CG  . ARG B 1 624 ? 169.877 212.678 217.470 1.00 70.93  ? 624 ARG B CG  1 
ATOM   6650 C CD  . ARG B 1 624 ? 171.251 212.488 218.095 1.00 70.92  ? 624 ARG B CD  1 
ATOM   6651 N NE  . ARG B 1 624 ? 171.884 213.757 218.436 1.00 73.57  ? 624 ARG B NE  1 
ATOM   6652 C CZ  . ARG B 1 624 ? 172.410 214.597 217.555 1.00 72.54  ? 624 ARG B CZ  1 
ATOM   6653 N NH1 . ARG B 1 624 ? 172.406 214.333 216.259 1.00 70.05  ? 624 ARG B NH1 1 
ATOM   6654 N NH2 . ARG B 1 624 ? 172.957 215.730 217.986 1.00 70.45  ? 624 ARG B NH2 1 
ATOM   6655 N N   . ALA B 1 625 ? 166.296 213.403 220.104 1.00 85.39  ? 625 ALA B N   1 
ATOM   6656 C CA  . ALA B 1 625 ? 165.509 214.004 221.175 1.00 88.89  ? 625 ALA B CA  1 
ATOM   6657 C C   . ALA B 1 625 ? 166.277 215.110 221.886 1.00 90.25  ? 625 ALA B C   1 
ATOM   6658 O O   . ALA B 1 625 ? 165.681 216.115 222.289 1.00 86.15  ? 625 ALA B O   1 
ATOM   6659 C CB  . ALA B 1 625 ? 165.074 212.932 222.174 1.00 88.80  ? 625 ALA B CB  1 
ATOM   6660 N N   . VAL B 1 626 ? 167.586 214.946 222.051 1.00 99.42  ? 626 VAL B N   1 
ATOM   6661 C CA  . VAL B 1 626 ? 168.411 215.950 222.711 1.00 99.89  ? 626 VAL B CA  1 
ATOM   6662 C C   . VAL B 1 626 ? 168.505 217.208 221.856 1.00 94.24  ? 626 VAL B C   1 
ATOM   6663 O O   . VAL B 1 626 ? 169.198 218.161 222.210 1.00 92.68  ? 626 VAL B O   1 
ATOM   6664 C CB  . VAL B 1 626 ? 169.814 215.399 223.020 1.00 96.50  ? 626 VAL B CB  1 
ATOM   6665 C CG1 . VAL B 1 626 ? 169.714 214.124 223.841 1.00 92.63  ? 626 VAL B CG1 1 
ATOM   6666 C CG2 . VAL B 1 626 ? 170.582 215.152 221.730 1.00 91.29  ? 626 VAL B CG2 1 
HETATM 6667 C C1  . CLR C 2 .   ? 203.002 177.348 205.545 1.00 64.45  ? 801 CLR A C1  1 
HETATM 6668 C C2  . CLR C 2 .   ? 202.770 178.282 206.728 1.00 62.75  ? 801 CLR A C2  1 
HETATM 6669 C C3  . CLR C 2 .   ? 203.590 177.849 207.926 1.00 60.52  ? 801 CLR A C3  1 
HETATM 6670 C C4  . CLR C 2 .   ? 205.066 177.787 207.546 1.00 58.85  ? 801 CLR A C4  1 
HETATM 6671 C C5  . CLR C 2 .   ? 205.307 176.922 206.338 1.00 56.70  ? 801 CLR A C5  1 
HETATM 6672 C C6  . CLR C 2 .   ? 206.152 175.895 206.408 1.00 57.39  ? 801 CLR A C6  1 
HETATM 6673 C C7  . CLR C 2 .   ? 206.542 175.031 205.256 1.00 51.05  ? 801 CLR A C7  1 
HETATM 6674 C C8  . CLR C 2 .   ? 206.041 175.569 203.922 1.00 49.97  ? 801 CLR A C8  1 
HETATM 6675 C C9  . CLR C 2 .   ? 204.600 176.079 204.068 1.00 56.49  ? 801 CLR A C9  1 
HETATM 6676 C C10 . CLR C 2 .   ? 204.476 177.229 205.104 1.00 58.79  ? 801 CLR A C10 1 
HETATM 6677 C C11 . CLR C 2 .   ? 203.992 176.421 202.703 1.00 61.66  ? 801 CLR A C11 1 
HETATM 6678 C C12 . CLR C 2 .   ? 204.127 175.299 201.669 1.00 64.12  ? 801 CLR A C12 1 
HETATM 6679 C C13 . CLR C 2 .   ? 205.585 174.876 201.471 1.00 58.06  ? 801 CLR A C13 1 
HETATM 6680 C C14 . CLR C 2 .   ? 206.099 174.480 202.865 1.00 55.22  ? 801 CLR A C14 1 
HETATM 6681 C C15 . CLR C 2 .   ? 207.439 173.809 202.602 1.00 62.83  ? 801 CLR A C15 1 
HETATM 6682 C C16 . CLR C 2 .   ? 207.220 173.089 201.259 1.00 54.06  ? 801 CLR A C16 1 
HETATM 6683 C C17 . CLR C 2 .   ? 205.846 173.554 200.701 1.00 48.46  ? 801 CLR A C17 1 
HETATM 6684 C C18 . CLR C 2 .   ? 206.405 176.010 200.850 1.00 59.71  ? 801 CLR A C18 1 
HETATM 6685 C C19 . CLR C 2 .   ? 204.940 178.572 204.522 1.00 61.89  ? 801 CLR A C19 1 
HETATM 6686 C C20 . CLR C 2 .   ? 205.833 173.531 199.164 1.00 52.81  ? 801 CLR A C20 1 
HETATM 6687 C C21 . CLR C 2 .   ? 204.438 173.646 198.555 1.00 61.33  ? 801 CLR A C21 1 
HETATM 6688 C C22 . CLR C 2 .   ? 206.527 172.254 198.666 1.00 56.19  ? 801 CLR A C22 1 
HETATM 6689 C C23 . CLR C 2 .   ? 206.282 171.882 197.207 1.00 60.77  ? 801 CLR A C23 1 
HETATM 6690 C C24 . CLR C 2 .   ? 205.616 170.516 197.069 1.00 63.25  ? 801 CLR A C24 1 
HETATM 6691 C C25 . CLR C 2 .   ? 206.503 169.410 196.495 1.00 58.73  ? 801 CLR A C25 1 
HETATM 6692 C C26 . CLR C 2 .   ? 205.815 168.055 196.626 1.00 57.43  ? 801 CLR A C26 1 
HETATM 6693 C C27 . CLR C 2 .   ? 206.880 169.673 195.040 1.00 59.03  ? 801 CLR A C27 1 
HETATM 6694 O O1  . CLR C 2 .   ? 203.359 178.757 208.983 1.00 62.85  ? 801 CLR A O1  1 
HETATM 6695 P P   . 3PE D 3 .   ? 218.440 196.086 209.714 1.00 88.83  ? 802 3PE A P   1 
HETATM 6696 N N   . 3PE D 3 .   ? 221.766 197.878 212.112 1.00 69.98  ? 802 3PE A N   1 
HETATM 6697 O O11 . 3PE D 3 .   ? 218.136 195.001 208.518 1.00 77.21  ? 802 3PE A O11 1 
HETATM 6698 O O12 . 3PE D 3 .   ? 218.434 197.420 209.048 1.00 73.94  ? 802 3PE A O12 1 
HETATM 6699 O O13 . 3PE D 3 .   ? 219.986 195.680 210.138 1.00 76.01  ? 802 3PE A O13 1 
HETATM 6700 O O14 . 3PE D 3 .   ? 217.620 195.757 210.916 1.00 68.28  ? 802 3PE A O14 1 
HETATM 6701 C C11 . 3PE D 3 .   ? 220.431 195.900 211.455 1.00 68.35  ? 802 3PE A C11 1 
HETATM 6702 C C12 . 3PE D 3 .   ? 220.420 197.388 211.720 1.00 71.95  ? 802 3PE A C12 1 
HETATM 6703 C C1  . 3PE D 3 .   ? 217.010 194.166 208.643 1.00 68.13  ? 802 3PE A C1  1 
HETATM 6704 C C2  . 3PE D 3 .   ? 217.042 193.072 207.583 1.00 66.90  ? 802 3PE A C2  1 
HETATM 6705 C C3  . 3PE D 3 .   ? 216.012 192.014 207.919 1.00 67.33  ? 802 3PE A C3  1 
HETATM 6706 O O31 . 3PE D 3 .   ? 216.578 190.745 207.606 1.00 70.69  ? 802 3PE A O31 1 
HETATM 6707 O O32 . 3PE D 3 .   ? 214.587 189.961 206.975 1.00 66.76  ? 802 3PE A O32 1 
HETATM 6708 C C31 . 3PE D 3 .   ? 215.764 189.789 207.165 1.00 70.52  ? 802 3PE A C31 1 
HETATM 6709 C C32 . 3PE D 3 .   ? 216.505 188.499 206.946 1.00 66.38  ? 802 3PE A C32 1 
HETATM 6710 C C33 . 3PE D 3 .   ? 216.261 187.874 205.584 1.00 61.87  ? 802 3PE A C33 1 
HETATM 6711 C C34 . 3PE D 3 .   ? 216.771 188.775 204.466 1.00 67.73  ? 802 3PE A C34 1 
HETATM 6712 C C35 . 3PE D 3 .   ? 218.216 189.217 204.664 1.00 66.58  ? 802 3PE A C35 1 
HETATM 6713 C C36 . 3PE D 3 .   ? 218.756 190.050 203.508 1.00 70.01  ? 802 3PE A C36 1 
HETATM 6714 C C37 . 3PE D 3 .   ? 218.187 189.673 202.146 1.00 59.02  ? 802 3PE A C37 1 
HETATM 6715 C C38 . 3PE D 3 .   ? 219.186 189.849 201.011 1.00 56.22  ? 802 3PE A C38 1 
HETATM 6716 C C39 . 3PE D 3 .   ? 218.657 190.678 199.848 1.00 64.78  ? 802 3PE A C39 1 
HETATM 6717 C C3A . 3PE D 3 .   ? 218.410 189.846 198.596 1.00 72.50  ? 802 3PE A C3A 1 
HETATM 6718 C C3B . 3PE D 3 .   ? 219.682 189.310 197.952 1.00 69.33  ? 802 3PE A C3B 1 
HETATM 6719 C C3C . 3PE D 3 .   ? 220.538 190.405 197.331 1.00 70.49  ? 802 3PE A C3C 1 
HETATM 6720 C C3D . 3PE D 3 .   ? 221.676 189.875 196.470 1.00 65.41  ? 802 3PE A C3D 1 
HETATM 6721 C C3E . 3PE D 3 .   ? 221.195 188.943 195.366 1.00 66.31  ? 802 3PE A C3E 1 
HETATM 6722 C C3F . 3PE D 3 .   ? 222.277 188.581 194.358 1.00 68.51  ? 802 3PE A C3F 1 
HETATM 6723 C C3G . 3PE D 3 .   ? 222.874 189.797 193.663 1.00 71.05  ? 802 3PE A C3G 1 
HETATM 6724 C C3H . 3PE D 3 .   ? 223.962 189.446 192.654 1.00 72.65  ? 802 3PE A C3H 1 
HETATM 6725 C C3I . 3PE D 3 .   ? 224.592 190.674 192.012 1.00 69.82  ? 802 3PE A C3I 1 
HETATM 6726 O O21 . 3PE D 3 .   ? 216.694 193.573 206.281 1.00 75.39  ? 802 3PE A O21 1 
HETATM 6727 O O22 . 3PE D 3 .   ? 216.249 191.866 204.904 1.00 72.79  ? 802 3PE A O22 1 
HETATM 6728 C C21 . 3PE D 3 .   ? 216.852 192.884 205.166 1.00 71.65  ? 802 3PE A C21 1 
HETATM 6729 C C22 . 3PE D 3 .   ? 217.845 193.519 204.237 1.00 69.14  ? 802 3PE A C22 1 
HETATM 6730 C C23 . 3PE D 3 .   ? 217.444 193.396 202.776 1.00 62.36  ? 802 3PE A C23 1 
HETATM 6731 C C24 . 3PE D 3 .   ? 218.033 194.511 201.923 1.00 60.92  ? 802 3PE A C24 1 
HETATM 6732 C C25 . 3PE D 3 .   ? 216.993 195.243 201.085 1.00 62.96  ? 802 3PE A C25 1 
HETATM 6733 C C26 . 3PE D 3 .   ? 216.338 194.352 200.038 1.00 68.36  ? 802 3PE A C26 1 
HETATM 6734 C C27 . 3PE D 3 .   ? 217.123 194.246 198.736 1.00 65.00  ? 802 3PE A C27 1 
HETATM 6735 C C28 . 3PE D 3 .   ? 217.258 195.581 198.014 1.00 66.91  ? 802 3PE A C28 1 
HETATM 6736 C C29 . 3PE D 3 .   ? 217.233 195.467 196.495 1.00 61.50  ? 802 3PE A C29 1 
HETATM 6737 C C2A . 3PE D 3 .   ? 218.476 194.808 195.909 1.00 62.53  ? 802 3PE A C2A 1 
HETATM 6738 C C2B . 3PE D 3 .   ? 218.664 195.103 194.426 1.00 72.07  ? 802 3PE A C2B 1 
HETATM 6739 C C2C . 3PE D 3 .   ? 219.821 194.340 193.790 1.00 70.51  ? 802 3PE A C2C 1 
HETATM 6740 C C2D . 3PE D 3 .   ? 220.109 194.779 192.359 1.00 66.40  ? 802 3PE A C2D 1 
HETATM 6741 C C2E . 3PE D 3 .   ? 220.750 193.697 191.497 1.00 64.51  ? 802 3PE A C2E 1 
HETATM 6742 C C2F . 3PE D 3 .   ? 221.058 194.171 190.081 1.00 68.75  ? 802 3PE A C2F 1 
HETATM 6743 C C2G . 3PE D 3 .   ? 221.534 193.064 189.148 1.00 71.00  ? 802 3PE A C2G 1 
HETATM 6744 C C2H . 3PE D 3 .   ? 220.398 192.272 188.512 1.00 67.66  ? 802 3PE A C2H 1 
HETATM 6745 C C2I . 3PE D 3 .   ? 220.841 191.475 187.293 1.00 62.93  ? 802 3PE A C2I 1 
HETATM 6746 P P   . 3PE E 3 .   ? 200.487 200.638 167.808 1.00 103.13 ? 803 3PE A P   1 
HETATM 6747 N N   . 3PE E 3 .   ? 196.993 203.282 165.537 1.00 78.49  ? 803 3PE A N   1 
HETATM 6748 O O11 . 3PE E 3 .   ? 200.839 201.304 169.269 1.00 80.83  ? 803 3PE A O11 1 
HETATM 6749 O O12 . 3PE E 3 .   ? 201.806 200.282 167.213 1.00 86.82  ? 803 3PE A O12 1 
HETATM 6750 O O13 . 3PE E 3 .   ? 199.847 201.934 167.005 1.00 83.64  ? 803 3PE A O13 1 
HETATM 6751 O O14 . 3PE E 3 .   ? 199.351 199.679 167.943 1.00 87.29  ? 803 3PE A O14 1 
HETATM 6752 C C11 . 3PE E 3 .   ? 198.857 201.727 166.025 1.00 77.43  ? 803 3PE A C11 1 
HETATM 6753 C C12 . 3PE E 3 .   ? 198.461 203.071 165.457 1.00 77.18  ? 803 3PE A C12 1 
HETATM 6754 C C1  . 3PE E 3 .   ? 199.844 202.034 169.949 1.00 77.50  ? 803 3PE A C1  1 
HETATM 6755 C C2  . 3PE E 3 .   ? 199.618 201.412 171.322 1.00 79.44  ? 803 3PE A C2  1 
HETATM 6756 C C3  . 3PE E 3 .   ? 199.163 199.972 171.216 1.00 78.67  ? 803 3PE A C3  1 
HETATM 6757 O O31 . 3PE E 3 .   ? 197.819 199.988 170.741 1.00 82.41  ? 803 3PE A O31 1 
HETATM 6758 O O32 . 3PE E 3 .   ? 196.304 198.357 170.879 1.00 79.60  ? 803 3PE A O32 1 
HETATM 6759 C C31 . 3PE E 3 .   ? 196.907 199.267 171.389 1.00 80.31  ? 803 3PE A C31 1 
HETATM 6760 C C32 . 3PE E 3 .   ? 196.741 199.740 172.807 1.00 74.85  ? 803 3PE A C32 1 
HETATM 6761 C C33 . 3PE E 3 .   ? 195.719 198.951 173.609 1.00 73.19  ? 803 3PE A C33 1 
HETATM 6762 C C34 . 3PE E 3 .   ? 195.886 199.189 175.104 1.00 77.13  ? 803 3PE A C34 1 
HETATM 6763 C C35 . 3PE E 3 .   ? 197.298 198.911 175.601 1.00 76.61  ? 803 3PE A C35 1 
HETATM 6764 C C36 . 3PE E 3 .   ? 197.400 198.928 177.120 1.00 78.49  ? 803 3PE A C36 1 
HETATM 6765 C C37 . 3PE E 3 .   ? 198.824 198.794 177.645 1.00 75.05  ? 803 3PE A C37 1 
HETATM 6766 C C38 . 3PE E 3 .   ? 198.898 198.889 179.163 1.00 76.36  ? 803 3PE A C38 1 
HETATM 6767 C C39 . 3PE E 3 .   ? 200.224 199.433 179.681 1.00 74.57  ? 803 3PE A C39 1 
HETATM 6768 C C3A . 3PE E 3 .   ? 200.124 199.963 181.106 1.00 72.73  ? 803 3PE A C3A 1 
HETATM 6769 C C3B . 3PE E 3 .   ? 201.142 201.049 181.427 1.00 72.64  ? 803 3PE A C3B 1 
HETATM 6770 C C3C . 3PE E 3 .   ? 200.840 201.773 182.732 1.00 75.31  ? 803 3PE A C3C 1 
HETATM 6771 C C3D . 3PE E 3 .   ? 200.979 200.899 183.971 1.00 76.63  ? 803 3PE A C3D 1 
HETATM 6772 C C3E . 3PE E 3 .   ? 200.433 201.557 185.231 1.00 72.24  ? 803 3PE A C3E 1 
HETATM 6773 C C3F . 3PE E 3 .   ? 201.509 202.024 186.202 1.00 68.93  ? 803 3PE A C3F 1 
HETATM 6774 C C3G . 3PE E 3 .   ? 200.933 202.592 187.492 1.00 75.02  ? 803 3PE A C3G 1 
HETATM 6775 C C3H . 3PE E 3 .   ? 201.984 202.891 188.555 1.00 76.94  ? 803 3PE A C3H 1 
HETATM 6776 C C3I . 3PE E 3 .   ? 202.952 203.991 188.142 1.00 77.13  ? 803 3PE A C3I 1 
HETATM 6777 O O21 . 3PE E 3 .   ? 200.816 201.371 172.110 1.00 81.33  ? 803 3PE A O21 1 
HETATM 6778 O O22 . 3PE E 3 .   ? 201.839 203.117 173.034 1.00 80.33  ? 803 3PE A O22 1 
HETATM 6779 C C21 . 3PE E 3 .   ? 201.009 202.234 173.084 1.00 82.58  ? 803 3PE A C21 1 
HETATM 6780 C C22 . 3PE E 3 .   ? 200.079 201.982 174.238 1.00 80.99  ? 803 3PE A C22 1 
HETATM 6781 C C23 . 3PE E 3 .   ? 200.695 201.217 175.397 1.00 77.76  ? 803 3PE A C23 1 
HETATM 6782 C C24 . 3PE E 3 .   ? 201.807 202.023 176.053 1.00 76.31  ? 803 3PE A C24 1 
HETATM 6783 C C25 . 3PE E 3 .   ? 202.396 201.365 177.293 1.00 77.59  ? 803 3PE A C25 1 
HETATM 6784 C C26 . 3PE E 3 .   ? 203.770 201.927 177.628 1.00 80.04  ? 803 3PE A C26 1 
HETATM 6785 C C27 . 3PE E 3 .   ? 204.255 201.605 179.034 1.00 75.74  ? 803 3PE A C27 1 
HETATM 6786 C C28 . 3PE E 3 .   ? 205.722 201.966 179.229 1.00 75.19  ? 803 3PE A C28 1 
HETATM 6787 C C29 . 3PE E 3 .   ? 206.115 202.205 180.680 1.00 73.09  ? 803 3PE A C29 1 
HETATM 6788 C C2A . 3PE E 3 .   ? 206.478 203.658 180.961 1.00 76.84  ? 803 3PE A C2A 1 
HETATM 6789 C C2B . 3PE E 3 .   ? 207.925 203.853 181.392 1.00 76.10  ? 803 3PE A C2B 1 
HETATM 6790 C C2C . 3PE E 3 .   ? 208.932 203.439 180.326 1.00 79.35  ? 803 3PE A C2C 1 
HETATM 6791 C C2D . 3PE E 3 .   ? 210.360 203.355 180.852 1.00 80.82  ? 803 3PE A C2D 1 
HETATM 6792 C C2E . 3PE E 3 .   ? 210.482 202.487 182.099 1.00 80.03  ? 803 3PE A C2E 1 
HETATM 6793 C C2F . 3PE E 3 .   ? 211.884 202.473 182.693 1.00 76.09  ? 803 3PE A C2F 1 
HETATM 6794 C C2G . 3PE E 3 .   ? 211.928 201.920 184.110 1.00 73.36  ? 803 3PE A C2G 1 
HETATM 6795 C C2H . 3PE E 3 .   ? 213.291 202.071 184.772 1.00 78.26  ? 803 3PE A C2H 1 
HETATM 6796 C C2I . 3PE E 3 .   ? 213.263 201.758 186.261 1.00 78.17  ? 803 3PE A C2I 1 
HETATM 6797 C C1  . CLR F 2 .   ? 239.633 176.739 179.604 1.00 80.07  ? 804 CLR A C1  1 
HETATM 6798 C C2  . CLR F 2 .   ? 239.612 176.980 178.099 1.00 81.62  ? 804 CLR A C2  1 
HETATM 6799 C C3  . CLR F 2 .   ? 238.386 176.352 177.465 1.00 82.22  ? 804 CLR A C3  1 
HETATM 6800 C C4  . CLR F 2 .   ? 237.120 176.874 178.141 1.00 82.17  ? 804 CLR A C4  1 
HETATM 6801 C C5  . CLR F 2 .   ? 237.162 176.711 179.638 1.00 82.01  ? 804 CLR A C5  1 
HETATM 6802 C C6  . CLR F 2 .   ? 236.208 176.027 180.267 1.00 80.74  ? 804 CLR A C6  1 
HETATM 6803 C C7  . CLR F 2 .   ? 236.096 175.895 181.748 1.00 81.75  ? 804 CLR A C7  1 
HETATM 6804 C C8  . CLR F 2 .   ? 237.054 176.822 182.488 1.00 80.82  ? 804 CLR A C8  1 
HETATM 6805 C C9  . CLR F 2 .   ? 238.435 176.783 181.818 1.00 79.43  ? 804 CLR A C9  1 
HETATM 6806 C C10 . CLR F 2 .   ? 238.387 177.267 180.345 1.00 81.62  ? 804 CLR A C10 1 
HETATM 6807 C C11 . CLR F 2 .   ? 239.489 177.509 182.663 1.00 79.51  ? 804 CLR A C11 1 
HETATM 6808 C C12 . CLR F 2 .   ? 239.510 177.096 184.138 1.00 79.37  ? 804 CLR A C12 1 
HETATM 6809 C C13 . CLR F 2 .   ? 238.137 177.250 184.795 1.00 77.86  ? 804 CLR A C13 1 
HETATM 6810 C C14 . CLR F 2 .   ? 237.173 176.408 183.944 1.00 77.62  ? 804 CLR A C14 1 
HETATM 6811 C C15 . CLR F 2 .   ? 235.896 176.311 184.769 1.00 81.24  ? 804 CLR A C15 1 
HETATM 6812 C C16 . CLR F 2 .   ? 236.386 176.392 186.226 1.00 79.14  ? 804 CLR A C16 1 
HETATM 6813 C C17 . CLR F 2 .   ? 237.927 176.576 186.177 1.00 79.97  ? 804 CLR A C17 1 
HETATM 6814 C C18 . CLR F 2 .   ? 237.722 178.723 184.864 1.00 78.31  ? 804 CLR A C18 1 
HETATM 6815 C C19 . CLR F 2 .   ? 238.345 178.799 180.251 1.00 81.98  ? 804 CLR A C19 1 
HETATM 6816 C C20 . CLR F 2 .   ? 238.452 177.239 187.460 1.00 81.87  ? 804 CLR A C20 1 
HETATM 6817 C C21 . CLR F 2 .   ? 239.951 177.053 187.681 1.00 83.17  ? 804 CLR A C21 1 
HETATM 6818 C C22 . CLR F 2 .   ? 237.677 176.696 188.670 1.00 76.87  ? 804 CLR A C22 1 
HETATM 6819 C C23 . CLR F 2 .   ? 237.893 177.435 189.986 1.00 78.35  ? 804 CLR A C23 1 
HETATM 6820 C C24 . CLR F 2 .   ? 236.917 178.594 190.161 1.00 79.05  ? 804 CLR A C24 1 
HETATM 6821 C C25 . CLR F 2 .   ? 237.468 179.979 189.819 1.00 78.71  ? 804 CLR A C25 1 
HETATM 6822 C C26 . CLR F 2 .   ? 236.402 181.041 190.065 1.00 74.43  ? 804 CLR A C26 1 
HETATM 6823 C C27 . CLR F 2 .   ? 238.730 180.308 190.611 1.00 82.02  ? 804 CLR A C27 1 
HETATM 6824 O O1  . CLR F 2 .   ? 238.399 176.640 176.082 1.00 82.13  ? 804 CLR A O1  1 
HETATM 6825 C C1  . CLR G 2 .   ? 205.327 210.166 173.420 1.00 95.90  ? 805 CLR A C1  1 
HETATM 6826 C C2  . CLR G 2 .   ? 205.982 209.792 172.094 1.00 96.81  ? 805 CLR A C2  1 
HETATM 6827 C C3  . CLR G 2 .   ? 205.009 209.922 170.939 1.00 95.83  ? 805 CLR A C3  1 
HETATM 6828 C C4  . CLR G 2 .   ? 203.767 209.063 171.170 1.00 96.11  ? 805 CLR A C4  1 
HETATM 6829 C C5  . CLR G 2 .   ? 203.660 208.524 172.573 1.00 98.70  ? 805 CLR A C5  1 
HETATM 6830 C C6  . CLR G 2 .   ? 203.227 207.281 172.779 1.00 96.83  ? 805 CLR A C6  1 
HETATM 6831 C C7  . CLR G 2 .   ? 202.969 206.673 174.117 1.00 93.62  ? 805 CLR A C7  1 
HETATM 6832 C C8  . CLR G 2 .   ? 202.965 207.696 175.247 1.00 95.76  ? 805 CLR A C8  1 
HETATM 6833 C C9  . CLR G 2 .   ? 204.093 208.717 175.044 1.00 96.42  ? 805 CLR A C9  1 
HETATM 6834 C C10 . CLR G 2 .   ? 203.969 209.489 173.705 1.00 99.00  ? 805 CLR A C10 1 
HETATM 6835 C C11 . CLR G 2 .   ? 204.239 209.639 176.260 1.00 95.89  ? 805 CLR A C11 1 
HETATM 6836 C C12 . CLR G 2 .   ? 204.340 208.898 177.596 1.00 97.83  ? 805 CLR A C12 1 
HETATM 6837 C C13 . CLR G 2 .   ? 203.165 207.939 177.807 1.00 99.85  ? 805 CLR A C13 1 
HETATM 6838 C C14 . CLR G 2 .   ? 203.149 207.004 176.587 1.00 99.76  ? 805 CLR A C14 1 
HETATM 6839 C C15 . CLR G 2 .   ? 202.182 205.891 176.968 1.00 99.94  ? 805 CLR A C15 1 
HETATM 6840 C C16 . CLR G 2 .   ? 202.385 205.739 178.488 1.00 98.95  ? 805 CLR A C16 1 
HETATM 6841 C C17 . CLR G 2 .   ? 203.310 206.900 178.948 1.00 98.51  ? 805 CLR A C17 1 
HETATM 6842 C C18 . CLR G 2 .   ? 201.849 208.709 177.966 1.00 94.95  ? 805 CLR A C18 1 
HETATM 6843 C C19 . CLR G 2 .   ? 202.857 210.547 173.768 1.00 98.98  ? 805 CLR A C19 1 
HETATM 6844 C C20 . CLR G 2 .   ? 203.040 207.337 180.397 1.00 96.14  ? 805 CLR A C20 1 
HETATM 6845 C C21 . CLR G 2 .   ? 204.261 207.952 181.078 1.00 94.23  ? 805 CLR A C21 1 
HETATM 6846 C C22 . CLR G 2 .   ? 202.497 206.159 181.223 1.00 95.39  ? 805 CLR A C22 1 
HETATM 6847 C C23 . CLR G 2 .   ? 203.516 205.434 182.096 1.00 95.58  ? 805 CLR A C23 1 
HETATM 6848 C C24 . CLR G 2 .   ? 202.861 204.724 183.275 1.00 95.15  ? 805 CLR A C24 1 
HETATM 6849 C C25 . CLR G 2 .   ? 203.270 205.246 184.654 1.00 95.52  ? 805 CLR A C25 1 
HETATM 6850 C C26 . CLR G 2 .   ? 202.772 206.675 184.850 1.00 95.42  ? 805 CLR A C26 1 
HETATM 6851 C C27 . CLR G 2 .   ? 204.780 205.182 184.867 1.00 96.77  ? 805 CLR A C27 1 
HETATM 6852 O O1  . CLR G 2 .   ? 204.678 211.288 170.788 1.00 97.17  ? 805 CLR A O1  1 
HETATM 6853 P P   . 3PE H 3 .   ? 199.337 189.764 210.026 1.00 82.39  ? 806 3PE A P   1 
HETATM 6854 N N   . 3PE H 3 .   ? 203.576 192.402 210.790 1.00 57.96  ? 806 3PE A N   1 
HETATM 6855 O O11 . 3PE H 3 .   ? 199.214 190.793 208.751 1.00 58.88  ? 806 3PE A O11 1 
HETATM 6856 O O12 . 3PE H 3 .   ? 198.069 189.936 210.792 1.00 60.97  ? 806 3PE A O12 1 
HETATM 6857 O O13 . 3PE H 3 .   ? 200.590 190.441 210.865 1.00 73.79  ? 806 3PE A O13 1 
HETATM 6858 O O14 . 3PE H 3 .   ? 199.855 188.443 209.566 1.00 66.15  ? 806 3PE A O14 1 
HETATM 6859 C C11 . 3PE H 3 .   ? 201.742 190.859 210.173 1.00 61.50  ? 806 3PE A C11 1 
HETATM 6860 C C12 . 3PE H 3 .   ? 202.814 191.191 211.185 1.00 62.49  ? 806 3PE A C12 1 
HETATM 6861 C C1  . 3PE H 3 .   ? 198.279 190.517 207.735 1.00 61.19  ? 806 3PE A C1  1 
HETATM 6862 C C2  . 3PE H 3 .   ? 199.025 190.090 206.477 1.00 60.29  ? 806 3PE A C2  1 
HETATM 6863 C C3  . 3PE H 3 .   ? 199.195 191.245 205.513 1.00 56.74  ? 806 3PE A C3  1 
HETATM 6864 O O31 . 3PE H 3 .   ? 198.975 190.730 204.203 1.00 51.26  ? 806 3PE A O31 1 
HETATM 6865 O O32 . 3PE H 3 .   ? 200.901 191.511 203.393 1.00 52.70  ? 806 3PE A O32 1 
HETATM 6866 C C31 . 3PE H 3 .   ? 199.991 190.725 203.344 1.00 54.09  ? 806 3PE A C31 1 
HETATM 6867 C C32 . 3PE H 3 .   ? 199.839 189.614 202.343 1.00 53.08  ? 806 3PE A C32 1 
HETATM 6868 C C33 . 3PE H 3 .   ? 200.711 189.750 201.106 1.00 48.85  ? 806 3PE A C33 1 
HETATM 6869 C C34 . 3PE H 3 .   ? 200.737 188.447 200.318 1.00 50.19  ? 806 3PE A C34 1 
HETATM 6870 C C35 . 3PE H 3 .   ? 200.780 188.641 198.808 1.00 57.21  ? 806 3PE A C35 1 
HETATM 6871 C C36 . 3PE H 3 .   ? 201.989 189.438 198.335 1.00 60.54  ? 806 3PE A C36 1 
HETATM 6872 C C37 . 3PE H 3 .   ? 202.393 189.157 196.892 1.00 65.06  ? 806 3PE A C37 1 
HETATM 6873 C C38 . 3PE H 3 .   ? 201.280 188.520 196.069 1.00 55.15  ? 806 3PE A C38 1 
HETATM 6874 C C39 . 3PE H 3 .   ? 201.765 187.626 194.934 1.00 55.25  ? 806 3PE A C39 1 
HETATM 6875 C C3A . 3PE H 3 .   ? 202.151 188.391 193.675 1.00 54.26  ? 806 3PE A C3A 1 
HETATM 6876 C C3B . 3PE H 3 .   ? 201.473 187.864 192.417 1.00 58.28  ? 806 3PE A C3B 1 
HETATM 6877 C C3C . 3PE H 3 .   ? 202.367 187.927 191.186 1.00 59.75  ? 806 3PE A C3C 1 
HETATM 6878 C C3D . 3PE H 3 .   ? 201.607 187.848 189.869 1.00 56.99  ? 806 3PE A C3D 1 
HETATM 6879 C C3E . 3PE H 3 .   ? 200.809 186.560 189.717 1.00 59.73  ? 806 3PE A C3E 1 
HETATM 6880 C C3F . 3PE H 3 .   ? 199.909 186.543 188.488 1.00 64.29  ? 806 3PE A C3F 1 
HETATM 6881 C C3G . 3PE H 3 .   ? 200.653 186.861 187.198 1.00 59.29  ? 806 3PE A C3G 1 
HETATM 6882 C C3H . 3PE H 3 .   ? 199.790 186.725 185.949 1.00 53.20  ? 806 3PE A C3H 1 
HETATM 6883 C C3I . 3PE H 3 .   ? 199.266 185.311 185.745 1.00 56.57  ? 806 3PE A C3I 1 
HETATM 6884 O O21 . 3PE H 3 .   ? 200.357 189.642 206.759 1.00 60.17  ? 806 3PE A O21 1 
HETATM 6885 O O22 . 3PE H 3 .   ? 201.697 188.924 205.135 1.00 70.30  ? 806 3PE A O22 1 
HETATM 6886 C C21 . 3PE H 3 .   ? 200.926 188.695 206.043 1.00 61.35  ? 806 3PE A C21 1 
HETATM 6887 C C22 . 3PE H 3 .   ? 200.516 187.324 206.502 1.00 52.88  ? 806 3PE A C22 1 
HETATM 6888 C C23 . 3PE H 3 .   ? 199.546 186.575 205.602 1.00 58.86  ? 806 3PE A C23 1 
HETATM 6889 C C24 . 3PE H 3 .   ? 200.128 186.307 204.220 1.00 65.85  ? 806 3PE A C24 1 
HETATM 6890 C C25 . 3PE H 3 .   ? 201.542 185.742 204.253 1.00 55.72  ? 806 3PE A C25 1 
HETATM 6891 C C26 . 3PE H 3 .   ? 201.627 184.321 203.714 1.00 53.92  ? 806 3PE A C26 1 
HETATM 6892 C C27 . 3PE H 3 .   ? 201.219 184.192 202.253 1.00 50.67  ? 806 3PE A C27 1 
HETATM 6893 C C28 . 3PE H 3 .   ? 202.008 185.109 201.328 1.00 52.77  ? 806 3PE A C28 1 
HETATM 6894 C C29 . 3PE H 3 .   ? 201.967 184.673 199.869 1.00 61.17  ? 806 3PE A C29 1 
HETATM 6895 C C2A . 3PE H 3 .   ? 200.589 184.198 199.428 1.00 60.86  ? 806 3PE A C2A 1 
HETATM 6896 C C2B . 3PE H 3 .   ? 200.567 183.642 198.012 1.00 53.69  ? 806 3PE A C2B 1 
HETATM 6897 C C2C . 3PE H 3 .   ? 200.926 184.684 196.961 1.00 52.81  ? 806 3PE A C2C 1 
HETATM 6898 C C2D . 3PE H 3 .   ? 200.788 184.176 195.531 1.00 62.53  ? 806 3PE A C2D 1 
HETATM 6899 C C2E . 3PE H 3 .   ? 201.843 183.146 195.148 1.00 59.65  ? 806 3PE A C2E 1 
HETATM 6900 C C2F . 3PE H 3 .   ? 201.761 182.727 193.686 1.00 60.82  ? 806 3PE A C2F 1 
HETATM 6901 C C2G . 3PE H 3 .   ? 200.359 182.311 193.262 1.00 62.05  ? 806 3PE A C2G 1 
HETATM 6902 C C2H . 3PE H 3 .   ? 200.276 181.856 191.811 1.00 62.70  ? 806 3PE A C2H 1 
HETATM 6903 C C2I . 3PE H 3 .   ? 201.144 180.640 191.522 1.00 62.04  ? 806 3PE A C2I 1 
HETATM 6904 C C1  . CLR I 2 .   ? 227.680 160.790 208.266 1.00 92.19  ? 807 CLR A C1  1 
HETATM 6905 C C2  . CLR I 2 .   ? 227.160 160.959 209.689 1.00 90.84  ? 807 CLR A C2  1 
HETATM 6906 C C3  . CLR I 2 .   ? 227.462 162.349 210.208 1.00 88.95  ? 807 CLR A C3  1 
HETATM 6907 C C4  . CLR I 2 .   ? 226.844 163.386 209.275 1.00 89.23  ? 807 CLR A C4  1 
HETATM 6908 C C5  . CLR I 2 .   ? 227.305 163.207 207.853 1.00 89.72  ? 807 CLR A C5  1 
HETATM 6909 C C6  . CLR I 2 .   ? 227.909 164.210 207.221 1.00 90.26  ? 807 CLR A C6  1 
HETATM 6910 C C7  . CLR I 2 .   ? 228.453 164.141 205.836 1.00 88.87  ? 807 CLR A C7  1 
HETATM 6911 C C8  . CLR I 2 .   ? 227.942 162.933 205.060 1.00 87.57  ? 807 CLR A C8  1 
HETATM 6912 C C9  . CLR I 2 .   ? 227.953 161.675 205.937 1.00 89.40  ? 807 CLR A C9  1 
HETATM 6913 C C10 . CLR I 2 .   ? 227.138 161.821 207.251 1.00 89.64  ? 807 CLR A C10 1 
HETATM 6914 C C11 . CLR I 2 .   ? 227.557 160.446 205.110 1.00 92.48  ? 807 CLR A C11 1 
HETATM 6915 C C12 . CLR I 2 .   ? 228.388 160.253 203.838 1.00 92.50  ? 807 CLR A C12 1 
HETATM 6916 C C13 . CLR I 2 .   ? 228.424 161.505 202.957 1.00 93.35  ? 807 CLR A C13 1 
HETATM 6917 C C14 . CLR I 2 .   ? 228.828 162.687 203.853 1.00 90.67  ? 807 CLR A C14 1 
HETATM 6918 C C15 . CLR I 2 .   ? 229.058 163.839 202.880 1.00 87.68  ? 807 CLR A C15 1 
HETATM 6919 C C16 . CLR I 2 .   ? 229.604 163.143 201.618 1.00 90.33  ? 807 CLR A C16 1 
HETATM 6920 C C17 . CLR I 2 .   ? 229.618 161.625 201.961 1.00 91.31  ? 807 CLR A C17 1 
HETATM 6921 C C18 . CLR I 2 .   ? 227.054 161.776 202.323 1.00 89.62  ? 807 CLR A C18 1 
HETATM 6922 C C19 . CLR I 2 .   ? 225.641 161.569 207.020 1.00 87.58  ? 807 CLR A C19 1 
HETATM 6923 C C20 . CLR I 2 .   ? 229.889 160.659 200.770 1.00 90.98  ? 807 CLR A C20 1 
HETATM 6924 C C21 . CLR I 2 .   ? 231.239 160.947 200.108 1.00 89.39  ? 807 CLR A C21 1 
HETATM 6925 C C22 . CLR I 2 .   ? 228.770 160.509 199.707 1.00 88.76  ? 807 CLR A C22 1 
HETATM 6926 C C23 . CLR I 2 .   ? 228.348 161.691 198.831 1.00 88.60  ? 807 CLR A C23 1 
HETATM 6927 C C24 . CLR I 2 .   ? 229.086 161.775 197.498 1.00 89.95  ? 807 CLR A C24 1 
HETATM 6928 C C25 . CLR I 2 .   ? 229.379 160.438 196.815 1.00 87.28  ? 807 CLR A C25 1 
HETATM 6929 C C26 . CLR I 2 .   ? 228.162 159.964 196.026 1.00 87.21  ? 807 CLR A C26 1 
HETATM 6930 C C27 . CLR I 2 .   ? 230.603 160.515 195.907 1.00 86.38  ? 807 CLR A C27 1 
HETATM 6931 O O1  . CLR I 2 .   ? 226.964 162.459 211.525 1.00 89.17  ? 807 CLR A O1  1 
HETATM 6932 C C1  . CLR J 2 .   ? 237.723 163.303 205.729 1.00 82.61  ? 808 CLR A C1  1 
HETATM 6933 C C2  . CLR J 2 .   ? 237.906 163.087 207.225 1.00 82.48  ? 808 CLR A C2  1 
HETATM 6934 C C3  . CLR J 2 .   ? 239.261 163.597 207.672 1.00 84.60  ? 808 CLR A C3  1 
HETATM 6935 C C4  . CLR J 2 .   ? 239.397 165.076 207.322 1.00 82.67  ? 808 CLR A C4  1 
HETATM 6936 C C5  . CLR J 2 .   ? 239.147 165.338 205.859 1.00 83.51  ? 808 CLR A C5  1 
HETATM 6937 C C6  . CLR J 2 .   ? 239.939 166.162 205.174 1.00 83.84  ? 808 CLR A C6  1 
HETATM 6938 C C7  . CLR J 2 .   ? 239.722 166.577 203.755 1.00 82.24  ? 808 CLR A C7  1 
HETATM 6939 C C8  . CLR J 2 .   ? 238.348 166.200 203.208 1.00 81.25  ? 808 CLR A C8  1 
HETATM 6940 C C9  . CLR J 2 .   ? 237.939 164.815 203.729 1.00 81.35  ? 808 CLR A C9  1 
HETATM 6941 C C10 . CLR J 2 .   ? 237.866 164.772 205.277 1.00 82.91  ? 808 CLR A C10 1 
HETATM 6942 C C11 . CLR J 2 .   ? 236.673 164.305 203.034 1.00 78.15  ? 808 CLR A C11 1 
HETATM 6943 C C12 . CLR J 2 .   ? 236.784 164.317 201.508 1.00 78.88  ? 808 CLR A C12 1 
HETATM 6944 C C13 . CLR J 2 .   ? 237.091 165.720 200.982 1.00 81.48  ? 808 CLR A C13 1 
HETATM 6945 C C14 . CLR J 2 .   ? 238.375 166.191 201.687 1.00 82.48  ? 808 CLR A C14 1 
HETATM 6946 C C15 . CLR J 2 .   ? 238.744 167.479 200.963 1.00 82.36  ? 808 CLR A C15 1 
HETATM 6947 C C16 . CLR J 2 .   ? 238.316 167.202 199.509 1.00 82.85  ? 808 CLR A C16 1 
HETATM 6948 C C17 . CLR J 2 .   ? 237.564 165.840 199.510 1.00 83.49  ? 808 CLR A C17 1 
HETATM 6949 C C18 . CLR J 2 .   ? 235.904 166.657 201.223 1.00 83.08  ? 808 CLR A C18 1 
HETATM 6950 C C19 . CLR J 2 .   ? 236.694 165.596 205.824 1.00 85.28  ? 808 CLR A C19 1 
HETATM 6951 C C20 . CLR J 2 .   ? 236.546 165.722 198.364 1.00 83.68  ? 808 CLR A C20 1 
HETATM 6952 C C21 . CLR J 2 .   ? 236.292 164.276 197.946 1.00 80.97  ? 808 CLR A C21 1 
HETATM 6953 C C22 . CLR J 2 .   ? 237.004 166.564 197.161 1.00 79.49  ? 808 CLR A C22 1 
HETATM 6954 C C23 . CLR J 2 .   ? 236.481 166.135 195.793 1.00 80.18  ? 808 CLR A C23 1 
HETATM 6955 C C24 . CLR J 2 .   ? 235.069 166.644 195.523 1.00 83.00  ? 808 CLR A C24 1 
HETATM 6956 C C25 . CLR J 2 .   ? 234.289 165.851 194.473 1.00 86.89  ? 808 CLR A C25 1 
HETATM 6957 C C26 . CLR J 2 .   ? 234.317 164.363 194.809 1.00 83.20  ? 808 CLR A C26 1 
HETATM 6958 C C27 . CLR J 2 .   ? 234.818 166.084 193.060 1.00 82.10  ? 808 CLR A C27 1 
HETATM 6959 O O1  . CLR J 2 .   ? 239.393 163.367 209.060 1.00 82.25  ? 808 CLR A O1  1 
HETATM 6960 C C1  . PLM K 4 .   ? 204.792 205.018 206.506 1.00 48.50  ? 809 PLM A C1  1 
HETATM 6961 O O1  . PLM K 4 .   ? 205.727 205.790 206.850 1.00 49.54  ? 809 PLM A O1  1 
HETATM 6962 O O2  . PLM K 4 .   ? 204.779 203.756 206.472 1.00 49.53  ? 809 PLM A O2  1 
HETATM 6963 C C2  . PLM K 4 .   ? 203.476 205.746 206.063 1.00 42.93  ? 809 PLM A C2  1 
HETATM 6964 C C3  . PLM K 4 .   ? 203.668 206.914 205.097 1.00 41.75  ? 809 PLM A C3  1 
HETATM 6965 C C4  . PLM K 4 .   ? 202.662 206.946 203.939 1.00 34.25  ? 809 PLM A C4  1 
HETATM 6966 C C5  . PLM K 4 .   ? 202.884 208.116 202.971 1.00 30.00  ? 809 PLM A C5  1 
HETATM 6967 C C6  . PLM K 4 .   ? 201.929 208.132 201.771 1.00 36.51  ? 809 PLM A C6  1 
HETATM 6968 C C7  . PLM K 4 .   ? 202.255 207.082 200.703 1.00 39.64  ? 809 PLM A C7  1 
HETATM 6969 C C8  . PLM K 4 .   ? 201.207 206.991 199.589 1.00 41.09  ? 809 PLM A C8  1 
HETATM 6970 C C9  . PLM K 4 .   ? 201.361 205.757 198.694 1.00 42.44  ? 809 PLM A C9  1 
HETATM 6971 C CA  . PLM K 4 .   ? 200.153 205.502 197.785 1.00 41.21  ? 809 PLM A CA  1 
HETATM 6972 C CB  . PLM K 4 .   ? 199.860 206.652 196.813 1.00 42.35  ? 809 PLM A CB  1 
HETATM 6973 C CC  . PLM K 4 .   ? 198.558 206.473 196.020 1.00 42.51  ? 809 PLM A CC  1 
HETATM 6974 C CD  . PLM K 4 .   ? 198.669 206.911 194.555 1.00 39.33  ? 809 PLM A CD  1 
HETATM 6975 C CE  . PLM K 4 .   ? 199.711 206.119 193.752 1.00 43.38  ? 809 PLM A CE  1 
HETATM 6976 C CF  . PLM K 4 .   ? 199.904 206.629 192.318 1.00 45.23  ? 809 PLM A CF  1 
HETATM 6977 C CG  . PLM K 4 .   ? 200.895 205.791 191.501 1.00 43.38  ? 809 PLM A CG  1 
HETATM 6978 C C1  . ACD L 5 .   ? 212.502 182.213 168.463 1.00 79.12  ? 810 ACD A C1  1 
HETATM 6979 C C2  . ACD L 5 .   ? 211.047 182.467 168.901 1.00 78.05  ? 810 ACD A C2  1 
HETATM 6980 C C3  . ACD L 5 .   ? 210.552 181.658 170.087 1.00 78.51  ? 810 ACD A C3  1 
HETATM 6981 C C4  . ACD L 5 .   ? 211.240 182.060 171.395 1.00 75.75  ? 810 ACD A C4  1 
HETATM 6982 C C5  . ACD L 5 .   ? 210.420 181.715 172.597 1.00 74.32  ? 810 ACD A C5  1 
HETATM 6983 C C6  . ACD L 5 .   ? 209.331 180.952 172.657 1.00 72.17  ? 810 ACD A C6  1 
HETATM 6984 C C7  . ACD L 5 .   ? 208.516 180.617 173.873 1.00 74.42  ? 810 ACD A C7  1 
HETATM 6985 C C8  . ACD L 5 .   ? 209.056 181.321 175.085 1.00 72.84  ? 810 ACD A C8  1 
HETATM 6986 C C9  . ACD L 5 .   ? 208.841 181.005 176.360 1.00 70.70  ? 810 ACD A C9  1 
HETATM 6987 C C10 . ACD L 5 .   ? 209.373 181.701 177.579 1.00 68.69  ? 810 ACD A C10 1 
HETATM 6988 C C11 . ACD L 5 .   ? 209.672 180.704 178.661 1.00 70.98  ? 810 ACD A C11 1 
HETATM 6989 C C12 . ACD L 5 .   ? 208.959 180.470 179.760 1.00 72.34  ? 810 ACD A C12 1 
HETATM 6990 C C13 . ACD L 5 .   ? 207.687 181.149 180.178 1.00 75.92  ? 810 ACD A C13 1 
HETATM 6991 C C14 . ACD L 5 .   ? 207.654 181.327 181.669 1.00 72.64  ? 810 ACD A C14 1 
HETATM 6992 C C15 . ACD L 5 .   ? 208.457 180.767 182.572 1.00 66.69  ? 810 ACD A C15 1 
HETATM 6993 C C16 . ACD L 5 .   ? 208.432 180.938 184.058 1.00 69.11  ? 810 ACD A C16 1 
HETATM 6994 C C17 . ACD L 5 .   ? 208.151 179.620 184.782 1.00 75.02  ? 810 ACD A C17 1 
HETATM 6995 C C18 . ACD L 5 .   ? 208.182 179.759 186.298 1.00 77.81  ? 810 ACD A C18 1 
HETATM 6996 C C19 . ACD L 5 .   ? 207.874 178.457 187.028 1.00 76.34  ? 810 ACD A C19 1 
HETATM 6997 C C20 . ACD L 5 .   ? 207.782 178.637 188.536 1.00 74.99  ? 810 ACD A C20 1 
HETATM 6998 O O1  . ACD L 5 .   ? 213.083 183.112 167.827 1.00 79.30  ? 810 ACD A O1  1 
HETATM 6999 O O2  . ACD L 5 .   ? 212.984 181.105 168.785 1.00 79.64  ? 810 ACD A O2  1 
HETATM 7000 C C1  . CLR M 2 .   ? 190.940 216.833 205.678 1.00 62.98  ? 801 CLR B C1  1 
HETATM 7001 C C2  . CLR M 2 .   ? 191.096 215.878 206.857 1.00 61.79  ? 801 CLR B C2  1 
HETATM 7002 C C3  . CLR M 2 .   ? 190.090 216.192 207.947 1.00 60.76  ? 801 CLR B C3  1 
HETATM 7003 C C4  . CLR M 2 .   ? 188.679 216.154 207.370 1.00 62.27  ? 801 CLR B C4  1 
HETATM 7004 C C5  . CLR M 2 .   ? 188.534 217.062 206.177 1.00 61.73  ? 801 CLR B C5  1 
HETATM 7005 C C6  . CLR M 2 .   ? 187.766 218.146 206.269 1.00 59.42  ? 801 CLR B C6  1 
HETATM 7006 C C7  . CLR M 2 .   ? 187.522 219.103 205.154 1.00 52.81  ? 801 CLR B C7  1 
HETATM 7007 C C8  . CLR M 2 .   ? 188.040 218.562 203.829 1.00 52.14  ? 801 CLR B C8  1 
HETATM 7008 C C9  . CLR M 2 .   ? 189.456 217.994 204.004 1.00 58.02  ? 801 CLR B C9  1 
HETATM 7009 C C10 . CLR M 2 .   ? 189.531 216.846 205.049 1.00 61.20  ? 801 CLR B C10 1 
HETATM 7010 C C11 . CLR M 2 .   ? 190.065 217.617 202.646 1.00 64.48  ? 801 CLR B C11 1 
HETATM 7011 C C12 . CLR M 2 .   ? 189.948 218.700 201.568 1.00 67.17  ? 801 CLR B C12 1 
HETATM 7012 C C13 . CLR M 2 .   ? 188.509 219.191 201.386 1.00 60.41  ? 801 CLR B C13 1 
HETATM 7013 C C14 . CLR M 2 .   ? 188.066 219.659 202.781 1.00 56.64  ? 801 CLR B C14 1 
HETATM 7014 C C15 . CLR M 2 .   ? 186.798 220.465 202.549 1.00 65.04  ? 801 CLR B C15 1 
HETATM 7015 C C16 . CLR M 2 .   ? 187.035 221.129 201.181 1.00 55.24  ? 801 CLR B C16 1 
HETATM 7016 C C17 . CLR M 2 .   ? 188.304 220.487 200.556 1.00 53.39  ? 801 CLR B C17 1 
HETATM 7017 C C18 . CLR M 2 .   ? 187.614 218.076 200.837 1.00 61.95  ? 801 CLR B C18 1 
HETATM 7018 C C19 . CLR M 2 .   ? 189.261 215.477 204.409 1.00 63.48  ? 801 CLR B C19 1 
HETATM 7019 C C20 . CLR M 2 .   ? 188.194 220.397 199.025 1.00 58.35  ? 801 CLR B C20 1 
HETATM 7020 C C21 . CLR M 2 .   ? 189.529 220.143 198.329 1.00 61.75  ? 801 CLR B C21 1 
HETATM 7021 C C22 . CLR M 2 .   ? 187.541 221.671 198.468 1.00 59.08  ? 801 CLR B C22 1 
HETATM 7022 C C23 . CLR M 2 .   ? 188.499 222.814 198.150 1.00 63.65  ? 801 CLR B C23 1 
HETATM 7023 C C24 . CLR M 2 .   ? 187.804 223.989 197.469 1.00 62.95  ? 801 CLR B C24 1 
HETATM 7024 C C25 . CLR M 2 .   ? 187.457 223.784 195.993 1.00 61.32  ? 801 CLR B C25 1 
HETATM 7025 C C26 . CLR M 2 .   ? 187.057 225.113 195.359 1.00 59.12  ? 801 CLR B C26 1 
HETATM 7026 C C27 . CLR M 2 .   ? 188.602 223.149 195.210 1.00 61.40  ? 801 CLR B C27 1 
HETATM 7027 O O1  . CLR M 2 .   ? 190.253 215.259 208.995 1.00 61.80  ? 801 CLR B O1  1 
HETATM 7028 P P   . 3PE N 3 .   ? 175.845 198.109 209.979 1.00 86.56  ? 802 3PE B P   1 
HETATM 7029 N N   . 3PE N 3 .   ? 173.284 195.384 212.550 1.00 76.45  ? 802 3PE B N   1 
HETATM 7030 O O11 . 3PE N 3 .   ? 175.909 199.235 208.783 1.00 79.88  ? 802 3PE B O11 1 
HETATM 7031 O O12 . 3PE N 3 .   ? 176.404 196.868 209.373 1.00 70.58  ? 802 3PE B O12 1 
HETATM 7032 O O13 . 3PE N 3 .   ? 174.215 197.935 210.197 1.00 80.16  ? 802 3PE B O13 1 
HETATM 7033 O O14 . 3PE N 3 .   ? 176.336 198.702 211.256 1.00 73.25  ? 802 3PE B O14 1 
HETATM 7034 C C11 . 3PE N 3 .   ? 173.719 197.566 211.462 1.00 75.37  ? 802 3PE B C11 1 
HETATM 7035 C C12 . 3PE N 3 .   ? 174.280 196.208 211.820 1.00 76.31  ? 802 3PE B C12 1 
HETATM 7036 C C1  . 3PE N 3 .   ? 177.175 199.641 208.322 1.00 71.11  ? 802 3PE B C1  1 
HETATM 7037 C C2  . 3PE N 3 .   ? 177.039 200.815 207.361 1.00 70.81  ? 802 3PE B C2  1 
HETATM 7038 C C3  . 3PE N 3 .   ? 177.881 201.980 207.840 1.00 71.53  ? 802 3PE B C3  1 
HETATM 7039 O O31 . 3PE N 3 .   ? 177.259 203.183 207.399 1.00 72.95  ? 802 3PE B O31 1 
HETATM 7040 O O32 . 3PE N 3 .   ? 179.242 204.140 207.030 1.00 67.75  ? 802 3PE B O32 1 
HETATM 7041 C C31 . 3PE N 3 .   ? 178.040 204.212 207.074 1.00 71.87  ? 802 3PE B C31 1 
HETATM 7042 C C32 . 3PE N 3 .   ? 177.225 205.441 206.784 1.00 69.90  ? 802 3PE B C32 1 
HETATM 7043 C C33 . 3PE N 3 .   ? 177.554 206.106 205.458 1.00 69.32  ? 802 3PE B C33 1 
HETATM 7044 C C34 . 3PE N 3 .   ? 177.136 205.237 204.278 1.00 69.89  ? 802 3PE B C34 1 
HETATM 7045 C C35 . 3PE N 3 .   ? 175.686 204.774 204.348 1.00 71.15  ? 802 3PE B C35 1 
HETATM 7046 C C36 . 3PE N 3 .   ? 175.229 204.051 203.086 1.00 69.40  ? 802 3PE B C36 1 
HETATM 7047 C C37 . 3PE N 3 .   ? 175.609 204.767 201.798 1.00 60.48  ? 802 3PE B C37 1 
HETATM 7048 C C38 . 3PE N 3 .   ? 174.707 204.428 200.620 1.00 65.44  ? 802 3PE B C38 1 
HETATM 7049 C C39 . 3PE N 3 .   ? 175.263 203.345 199.707 1.00 68.94  ? 802 3PE B C39 1 
HETATM 7050 C C3A . 3PE N 3 .   ? 175.638 203.882 198.332 1.00 74.57  ? 802 3PE B C3A 1 
HETATM 7051 C C3B . 3PE N 3 .   ? 174.487 204.569 197.609 1.00 70.61  ? 802 3PE B C3B 1 
HETATM 7052 C C3C . 3PE N 3 .   ? 173.422 203.596 197.120 1.00 73.65  ? 802 3PE B C3C 1 
HETATM 7053 C C3D . 3PE N 3 .   ? 172.302 204.266 196.337 1.00 69.87  ? 802 3PE B C3D 1 
HETATM 7054 C C3E . 3PE N 3 .   ? 172.816 205.208 195.258 1.00 72.40  ? 802 3PE B C3E 1 
HETATM 7055 C C3F . 3PE N 3 .   ? 171.745 205.642 194.267 1.00 72.58  ? 802 3PE B C3F 1 
HETATM 7056 C C3G . 3PE N 3 .   ? 171.137 204.474 193.502 1.00 74.35  ? 802 3PE B C3G 1 
HETATM 7057 C C3H . 3PE N 3 .   ? 170.039 204.889 192.530 1.00 76.00  ? 802 3PE B C3H 1 
HETATM 7058 C C3I . 3PE N 3 .   ? 169.407 203.706 191.811 1.00 73.03  ? 802 3PE B C3I 1 
HETATM 7059 O O21 . 3PE N 3 .   ? 177.540 200.481 206.057 1.00 79.16  ? 802 3PE B O21 1 
HETATM 7060 O O22 . 3PE N 3 .   ? 178.005 202.216 204.737 1.00 79.92  ? 802 3PE B O22 1 
HETATM 7061 C C21 . 3PE N 3 .   ? 177.347 201.231 204.990 1.00 76.49  ? 802 3PE B C21 1 
HETATM 7062 C C22 . 3PE N 3 .   ? 176.247 200.706 204.115 1.00 72.84  ? 802 3PE B C22 1 
HETATM 7063 C C23 . 3PE N 3 .   ? 176.611 200.699 202.640 1.00 69.26  ? 802 3PE B C23 1 
HETATM 7064 C C24 . 3PE N 3 .   ? 176.044 199.485 201.916 1.00 68.83  ? 802 3PE B C24 1 
HETATM 7065 C C25 . 3PE N 3 .   ? 177.088 198.730 201.105 1.00 66.86  ? 802 3PE B C25 1 
HETATM 7066 C C26 . 3PE N 3 .   ? 177.777 199.604 200.066 1.00 71.22  ? 802 3PE B C26 1 
HETATM 7067 C C27 . 3PE N 3 .   ? 176.995 199.758 198.768 1.00 69.85  ? 802 3PE B C27 1 
HETATM 7068 C C28 . 3PE N 3 .   ? 176.815 198.440 198.024 1.00 72.51  ? 802 3PE B C28 1 
HETATM 7069 C C29 . 3PE N 3 .   ? 176.872 198.573 196.508 1.00 66.36  ? 802 3PE B C29 1 
HETATM 7070 C C2A . 3PE N 3 .   ? 175.661 199.277 195.908 1.00 65.08  ? 802 3PE B C2A 1 
HETATM 7071 C C2B . 3PE N 3 .   ? 175.458 198.961 194.432 1.00 73.13  ? 802 3PE B C2B 1 
HETATM 7072 C C2C . 3PE N 3 .   ? 174.315 199.738 193.789 1.00 72.11  ? 802 3PE B C2C 1 
HETATM 7073 C C2D . 3PE N 3 .   ? 174.023 199.295 192.360 1.00 70.49  ? 802 3PE B C2D 1 
HETATM 7074 C C2E . 3PE N 3 .   ? 173.395 200.379 191.492 1.00 68.76  ? 802 3PE B C2E 1 
HETATM 7075 C C2F . 3PE N 3 .   ? 173.056 199.893 190.088 1.00 74.07  ? 802 3PE B C2F 1 
HETATM 7076 C C2G . 3PE N 3 .   ? 172.572 200.994 189.152 1.00 74.89  ? 802 3PE B C2G 1 
HETATM 7077 C C2H . 3PE N 3 .   ? 173.700 201.820 188.547 1.00 73.27  ? 802 3PE B C2H 1 
HETATM 7078 C C2I . 3PE N 3 .   ? 173.261 202.620 187.329 1.00 67.41  ? 802 3PE B C2I 1 
HETATM 7079 P P   . 3PE O 3 .   ? 193.262 193.153 167.610 1.00 102.93 ? 803 3PE B P   1 
HETATM 7080 N N   . 3PE O 3 .   ? 197.320 191.025 165.711 1.00 83.14  ? 803 3PE B N   1 
HETATM 7081 O O11 . 3PE O 3 .   ? 193.178 192.621 169.163 1.00 84.95  ? 803 3PE B O11 1 
HETATM 7082 O O12 . 3PE O 3 .   ? 191.869 193.059 167.088 1.00 89.42  ? 803 3PE B O12 1 
HETATM 7083 O O13 . 3PE O 3 .   ? 194.196 191.980 166.912 1.00 86.15  ? 803 3PE B O13 1 
HETATM 7084 O O14 . 3PE O 3 .   ? 194.093 194.390 167.540 1.00 90.99  ? 803 3PE B O14 1 
HETATM 7085 C C11 . 3PE O 3 .   ? 195.254 192.346 166.058 1.00 81.74  ? 803 3PE B C11 1 
HETATM 7086 C C12 . 3PE O 3 .   ? 195.855 191.085 165.479 1.00 81.27  ? 803 3PE B C12 1 
HETATM 7087 C C1  . 3PE O 3 .   ? 194.334 192.096 169.772 1.00 81.51  ? 803 3PE B C1  1 
HETATM 7088 C C2  . 3PE O 3 .   ? 194.491 192.712 171.158 1.00 82.21  ? 803 3PE B C2  1 
HETATM 7089 C C3  . 3PE O 3 .   ? 194.928 194.160 171.076 1.00 81.91  ? 803 3PE B C3  1 
HETATM 7090 O O31 . 3PE O 3 .   ? 196.259 194.172 170.567 1.00 85.69  ? 803 3PE B O31 1 
HETATM 7091 O O32 . 3PE O 3 .   ? 197.737 195.833 170.748 1.00 81.74  ? 803 3PE B O32 1 
HETATM 7092 C C31 . 3PE O 3 .   ? 197.182 194.874 171.221 1.00 83.42  ? 803 3PE B C31 1 
HETATM 7093 C C32 . 3PE O 3 .   ? 197.425 194.313 172.595 1.00 79.59  ? 803 3PE B C32 1 
HETATM 7094 C C33 . 3PE O 3 .   ? 198.391 195.128 173.437 1.00 76.61  ? 803 3PE B C33 1 
HETATM 7095 C C34 . 3PE O 3 .   ? 198.195 194.853 174.923 1.00 77.61  ? 803 3PE B C34 1 
HETATM 7096 C C35 . 3PE O 3 .   ? 196.740 194.956 175.360 1.00 79.30  ? 803 3PE B C35 1 
HETATM 7097 C C36 . 3PE O 3 .   ? 196.586 195.077 176.869 1.00 80.42  ? 803 3PE B C36 1 
HETATM 7098 C C37 . 3PE O 3 .   ? 195.136 195.136 177.334 1.00 77.83  ? 803 3PE B C37 1 
HETATM 7099 C C38 . 3PE O 3 .   ? 195.012 195.360 178.834 1.00 79.37  ? 803 3PE B C38 1 
HETATM 7100 C C39 . 3PE O 3 .   ? 194.061 194.393 179.527 1.00 79.37  ? 803 3PE B C39 1 
HETATM 7101 C C3A . 3PE O 3 .   ? 194.132 194.505 181.044 1.00 75.85  ? 803 3PE B C3A 1 
HETATM 7102 C C3B . 3PE O 3 .   ? 193.427 193.378 181.786 1.00 73.43  ? 803 3PE B C3B 1 
HETATM 7103 C C3C . 3PE O 3 .   ? 193.751 193.383 183.273 1.00 77.15  ? 803 3PE B C3C 1 
HETATM 7104 C C3D . 3PE O 3 .   ? 192.936 192.391 184.090 1.00 76.10  ? 803 3PE B C3D 1 
HETATM 7105 C C3E . 3PE O 3 .   ? 193.247 192.462 185.578 1.00 75.04  ? 803 3PE B C3E 1 
HETATM 7106 C C3F . 3PE O 3 .   ? 192.392 191.527 186.421 1.00 75.48  ? 803 3PE B C3F 1 
HETATM 7107 C C3G . 3PE O 3 .   ? 192.755 191.557 187.899 1.00 80.05  ? 803 3PE B C3G 1 
HETATM 7108 C C3H . 3PE O 3 .   ? 191.961 190.560 188.734 1.00 83.62  ? 803 3PE B C3H 1 
HETATM 7109 C C3I . 3PE O 3 .   ? 192.102 189.130 188.232 1.00 85.10  ? 803 3PE B C3I 1 
HETATM 7110 O O21 . 3PE O 3 .   ? 193.261 192.733 171.894 1.00 84.31  ? 803 3PE B O21 1 
HETATM 7111 O O22 . 3PE O 3 .   ? 192.139 190.987 172.699 1.00 83.00  ? 803 3PE B O22 1 
HETATM 7112 C C21 . 3PE O 3 .   ? 193.010 191.824 172.813 1.00 84.11  ? 803 3PE B C21 1 
HETATM 7113 C C22 . 3PE O 3 .   ? 193.930 191.961 173.993 1.00 82.17  ? 803 3PE B C22 1 
HETATM 7114 C C23 . 3PE O 3 .   ? 193.351 192.726 175.171 1.00 81.13  ? 803 3PE B C23 1 
HETATM 7115 C C24 . 3PE O 3 .   ? 192.153 191.999 175.766 1.00 80.93  ? 803 3PE B C24 1 
HETATM 7116 C C25 . 3PE O 3 .   ? 191.708 192.554 177.113 1.00 80.15  ? 803 3PE B C25 1 
HETATM 7117 C C26 . 3PE O 3 .   ? 190.262 192.198 177.428 1.00 83.31  ? 803 3PE B C26 1 
HETATM 7118 C C27 . 3PE O 3 .   ? 189.876 192.386 178.888 1.00 79.20  ? 803 3PE B C27 1 
HETATM 7119 C C28 . 3PE O 3 .   ? 188.366 192.409 179.093 1.00 79.29  ? 803 3PE B C28 1 
HETATM 7120 C C29 . 3PE O 3 .   ? 187.935 192.095 180.519 1.00 77.45  ? 803 3PE B C29 1 
HETATM 7121 C C2A . 3PE O 3 .   ? 187.754 190.604 180.775 1.00 82.05  ? 803 3PE B C2A 1 
HETATM 7122 C C2B . 3PE O 3 .   ? 186.352 190.243 181.245 1.00 80.94  ? 803 3PE B C2B 1 
HETATM 7123 C C2C . 3PE O 3 .   ? 185.271 190.625 180.241 1.00 83.56  ? 803 3PE B C2C 1 
HETATM 7124 C C2D . 3PE O 3 .   ? 183.873 190.681 180.845 1.00 84.96  ? 803 3PE B C2D 1 
HETATM 7125 C C2E . 3PE O 3 .   ? 183.775 191.613 182.047 1.00 82.55  ? 803 3PE B C2E 1 
HETATM 7126 C C2F . 3PE O 3 .   ? 182.348 191.796 182.549 1.00 78.91  ? 803 3PE B C2F 1 
HETATM 7127 C C2G . 3PE O 3 .   ? 182.259 191.965 184.059 1.00 78.81  ? 803 3PE B C2G 1 
HETATM 7128 C C2H . 3PE O 3 .   ? 180.839 191.818 184.593 1.00 82.44  ? 803 3PE B C2H 1 
HETATM 7129 C C2I . 3PE O 3 .   ? 180.797 191.499 186.080 1.00 81.89  ? 803 3PE B C2I 1 
HETATM 7130 C C1  . CLR P 2 .   ? 188.362 183.870 173.263 1.00 106.86 ? 804 CLR B C1  1 
HETATM 7131 C C2  . CLR P 2 .   ? 187.793 184.263 171.904 1.00 107.19 ? 804 CLR B C2  1 
HETATM 7132 C C3  . CLR P 2 .   ? 188.768 183.960 170.783 1.00 105.66 ? 804 CLR B C3  1 
HETATM 7133 C C4  . CLR P 2 .   ? 190.106 184.661 171.015 1.00 105.19 ? 804 CLR B C4  1 
HETATM 7134 C C5  . CLR P 2 .   ? 190.249 185.242 172.397 1.00 107.96 ? 804 CLR B C5  1 
HETATM 7135 C C6  . CLR P 2 .   ? 190.820 186.434 172.565 1.00 106.53 ? 804 CLR B C6  1 
HETATM 7136 C C7  . CLR P 2 .   ? 191.141 187.054 173.884 1.00 104.06 ? 804 CLR B C7  1 
HETATM 7137 C C8  . CLR P 2 .   ? 190.993 186.085 175.052 1.00 105.89 ? 804 CLR B C8  1 
HETATM 7138 C C9  . CLR P 2 .   ? 189.741 185.216 174.860 1.00 107.07 ? 804 CLR B C9  1 
HETATM 7139 C C10 . CLR P 2 .   ? 189.791 184.376 173.558 1.00 108.61 ? 804 CLR B C10 1 
HETATM 7140 C C11 . CLR P 2 .   ? 189.443 184.378 176.109 1.00 105.05 ? 804 CLR B C11 1 
HETATM 7141 C C12 . CLR P 2 .   ? 189.406 185.191 177.405 1.00 107.38 ? 804 CLR B C12 1 
HETATM 7142 C C13 . CLR P 2 .   ? 190.698 185.983 177.617 1.00 109.42 ? 804 CLR B C13 1 
HETATM 7143 C C14 . CLR P 2 .   ? 190.887 186.849 176.361 1.00 107.52 ? 804 CLR B C14 1 
HETATM 7144 C C15 . CLR P 2 .   ? 192.007 187.812 176.731 1.00 107.76 ? 804 CLR B C15 1 
HETATM 7145 C C16 . CLR P 2 .   ? 191.763 188.084 178.228 1.00 108.28 ? 804 CLR B C16 1 
HETATM 7146 C C17 . CLR P 2 .   ? 190.669 187.087 178.706 1.00 108.80 ? 804 CLR B C17 1 
HETATM 7147 C C18 . CLR P 2 .   ? 191.884 185.044 177.859 1.00 105.15 ? 804 CLR B C18 1 
HETATM 7148 C C19 . CLR P 2 .   ? 190.753 183.185 173.695 1.00 107.31 ? 804 CLR B C19 1 
HETATM 7149 C C20 . CLR P 2 .   ? 190.833 186.690 180.182 1.00 106.51 ? 804 CLR B C20 1 
HETATM 7150 C C21 . CLR P 2 .   ? 189.523 186.259 180.840 1.00 104.67 ? 804 CLR B C21 1 
HETATM 7151 C C22 . CLR P 2 .   ? 191.494 187.830 180.975 1.00 105.11 ? 804 CLR B C22 1 
HETATM 7152 C C23 . CLR P 2 .   ? 190.591 188.589 181.943 1.00 103.79 ? 804 CLR B C23 1 
HETATM 7153 C C24 . CLR P 2 .   ? 191.374 189.204 183.097 1.00 103.99 ? 804 CLR B C24 1 
HETATM 7154 C C25 . CLR P 2 .   ? 191.029 188.651 184.481 1.00 105.55 ? 804 CLR B C25 1 
HETATM 7155 C C26 . CLR P 2 .   ? 191.460 187.191 184.593 1.00 105.34 ? 804 CLR B C26 1 
HETATM 7156 C C27 . CLR P 2 .   ? 189.543 188.786 184.799 1.00 105.86 ? 804 CLR B C27 1 
HETATM 7157 O O1  . CLR P 2 .   ? 188.922 182.558 170.694 1.00 105.69 ? 804 CLR B O1  1 
HETATM 7158 P P   . 3PE Q 3 .   ? 194.978 204.190 209.750 1.00 79.02  ? 805 3PE B P   1 
HETATM 7159 N N   . 3PE Q 3 .   ? 190.660 201.581 209.962 1.00 54.57  ? 805 3PE B N   1 
HETATM 7160 O O11 . 3PE Q 3 .   ? 195.281 203.325 208.385 1.00 61.51  ? 805 3PE B O11 1 
HETATM 7161 O O12 . 3PE Q 3 .   ? 196.206 204.054 210.583 1.00 60.64  ? 805 3PE B O12 1 
HETATM 7162 O O13 . 3PE Q 3 .   ? 193.752 203.306 210.421 1.00 68.93  ? 805 3PE B O13 1 
HETATM 7163 O O14 . 3PE Q 3 .   ? 194.355 205.498 209.399 1.00 62.73  ? 805 3PE B O14 1 
HETATM 7164 C C11 . 3PE Q 3 .   ? 192.525 203.193 209.741 1.00 61.63  ? 805 3PE B C11 1 
HETATM 7165 C C12 . 3PE Q 3 .   ? 191.517 202.562 210.674 1.00 61.40  ? 805 3PE B C12 1 
HETATM 7166 C C1  . 3PE Q 3 .   ? 196.135 203.863 207.401 1.00 61.47  ? 805 3PE B C1  1 
HETATM 7167 C C2  . 3PE Q 3 .   ? 195.296 204.318 206.213 1.00 56.98  ? 805 3PE B C2  1 
HETATM 7168 C C3  . 3PE Q 3 .   ? 195.391 203.347 205.055 1.00 54.07  ? 805 3PE B C3  1 
HETATM 7169 O O31 . 3PE Q 3 .   ? 195.131 204.081 203.861 1.00 52.05  ? 805 3PE B O31 1 
HETATM 7170 O O32 . 3PE Q 3 .   ? 193.577 202.608 203.243 1.00 55.60  ? 805 3PE B O32 1 
HETATM 7171 C C31 . 3PE Q 3 .   ? 194.187 203.627 203.041 1.00 55.52  ? 805 3PE B C31 1 
HETATM 7172 C C32 . 3PE Q 3 .   ? 193.992 204.543 201.864 1.00 50.66  ? 805 3PE B C32 1 
HETATM 7173 C C33 . 3PE Q 3 .   ? 192.885 204.105 200.919 1.00 51.42  ? 805 3PE B C33 1 
HETATM 7174 C C34 . 3PE Q 3 .   ? 192.420 205.250 200.028 1.00 49.33  ? 805 3PE B C34 1 
HETATM 7175 C C35 . 3PE Q 3 .   ? 193.403 205.596 198.918 1.00 57.02  ? 805 3PE B C35 1 
HETATM 7176 C C36 . 3PE Q 3 .   ? 193.436 204.544 197.817 1.00 59.73  ? 805 3PE B C36 1 
HETATM 7177 C C37 . 3PE Q 3 .   ? 192.271 204.633 196.839 1.00 59.67  ? 805 3PE B C37 1 
HETATM 7178 C C38 . 3PE Q 3 .   ? 192.457 205.728 195.796 1.00 54.11  ? 805 3PE B C38 1 
HETATM 7179 C C39 . 3PE Q 3 .   ? 191.293 205.859 194.821 1.00 54.30  ? 805 3PE B C39 1 
HETATM 7180 C C3A . 3PE Q 3 .   ? 191.235 204.725 193.806 1.00 57.20  ? 805 3PE B C3A 1 
HETATM 7181 C C3B . 3PE Q 3 .   ? 192.226 204.881 192.662 1.00 59.79  ? 805 3PE B C3B 1 
HETATM 7182 C C3C . 3PE Q 3 .   ? 192.009 206.161 191.866 1.00 55.49  ? 805 3PE B C3C 1 
HETATM 7183 C C3D . 3PE Q 3 .   ? 192.947 206.305 190.676 1.00 56.33  ? 805 3PE B C3D 1 
HETATM 7184 C C3E . 3PE Q 3 .   ? 192.786 207.631 189.946 1.00 54.55  ? 805 3PE B C3E 1 
HETATM 7185 C C3F . 3PE Q 3 .   ? 193.757 207.807 188.787 1.00 62.04  ? 805 3PE B C3F 1 
HETATM 7186 C C3G . 3PE Q 3 .   ? 193.575 206.763 187.694 1.00 60.92  ? 805 3PE B C3G 1 
HETATM 7187 C C3H . 3PE Q 3 .   ? 194.505 206.962 186.503 1.00 55.19  ? 805 3PE B C3H 1 
HETATM 7188 C C3I . 3PE Q 3 .   ? 194.321 208.314 185.828 1.00 53.40  ? 805 3PE B C3I 1 
HETATM 7189 O O21 . 3PE Q 3 .   ? 193.900 204.391 206.532 1.00 57.38  ? 805 3PE B O21 1 
HETATM 7190 O O22 . 3PE Q 3 .   ? 192.333 204.949 205.056 1.00 67.59  ? 805 3PE B O22 1 
HETATM 7191 C C21 . 3PE Q 3 .   ? 193.097 205.256 205.946 1.00 60.31  ? 805 3PE B C21 1 
HETATM 7192 C C22 . 3PE Q 3 .   ? 193.229 206.635 206.528 1.00 51.63  ? 805 3PE B C22 1 
HETATM 7193 C C23 . 3PE Q 3 .   ? 194.096 207.626 205.766 1.00 57.64  ? 805 3PE B C23 1 
HETATM 7194 C C24 . 3PE Q 3 .   ? 193.731 207.704 204.290 1.00 64.29  ? 805 3PE B C24 1 
HETATM 7195 C C25 . 3PE Q 3 .   ? 192.293 208.138 204.044 1.00 55.92  ? 805 3PE B C25 1 
HETATM 7196 C C26 . 3PE Q 3 .   ? 192.183 209.579 203.567 1.00 51.68  ? 805 3PE B C26 1 
HETATM 7197 C C27 . 3PE Q 3 .   ? 192.717 209.802 202.159 1.00 46.99  ? 805 3PE B C27 1 
HETATM 7198 C C28 . 3PE Q 3 .   ? 192.188 208.785 201.155 1.00 49.36  ? 805 3PE B C28 1 
HETATM 7199 C C29 . 3PE Q 3 .   ? 192.124 209.309 199.727 1.00 58.63  ? 805 3PE B C29 1 
HETATM 7200 C C2A . 3PE Q 3 .   ? 193.380 210.058 199.302 1.00 61.10  ? 805 3PE B C2A 1 
HETATM 7201 C C2B . 3PE Q 3 .   ? 193.420 210.367 197.812 1.00 54.70  ? 805 3PE B C2B 1 
HETATM 7202 C C2C . 3PE Q 3 .   ? 193.523 209.114 196.951 1.00 56.81  ? 805 3PE B C2C 1 
HETATM 7203 C C2D . 3PE Q 3 .   ? 193.474 209.400 195.455 1.00 62.20  ? 805 3PE B C2D 1 
HETATM 7204 C C2E . 3PE Q 3 .   ? 192.149 210.002 195.003 1.00 58.07  ? 805 3PE B C2E 1 
HETATM 7205 C C2F . 3PE Q 3 .   ? 191.995 210.058 193.488 1.00 63.31  ? 805 3PE B C2F 1 
HETATM 7206 C C2G . 3PE Q 3 .   ? 192.892 211.095 192.827 1.00 58.30  ? 805 3PE B C2G 1 
HETATM 7207 C C2H . 3PE Q 3 .   ? 192.780 211.104 191.307 1.00 55.59  ? 805 3PE B C2H 1 
HETATM 7208 C C2I . 3PE Q 3 .   ? 191.342 211.216 190.819 1.00 53.66  ? 805 3PE B C2I 1 
HETATM 7209 C C1  . CLR R 2 .   ? 166.158 233.234 208.562 1.00 93.83  ? 806 CLR B C1  1 
HETATM 7210 C C2  . CLR R 2 .   ? 166.646 233.046 209.993 1.00 92.78  ? 806 CLR B C2  1 
HETATM 7211 C C3  . CLR R 2 .   ? 166.530 231.593 210.405 1.00 91.07  ? 806 CLR B C3  1 
HETATM 7212 C C4  . CLR R 2 .   ? 167.343 230.726 209.449 1.00 91.19  ? 806 CLR B C4  1 
HETATM 7213 C C5  . CLR R 2 .   ? 166.937 230.933 208.013 1.00 91.19  ? 806 CLR B C5  1 
HETATM 7214 C C6  . CLR R 2 .   ? 166.728 229.886 207.216 1.00 91.26  ? 806 CLR B C6  1 
HETATM 7215 C C7  . CLR R 2 .   ? 166.387 229.965 205.765 1.00 90.33  ? 806 CLR B C7  1 
HETATM 7216 C C8  . CLR R 2 .   ? 166.537 231.364 205.176 1.00 89.26  ? 806 CLR B C8  1 
HETATM 7217 C C9  . CLR R 2 .   ? 166.074 232.420 206.190 1.00 92.48  ? 806 CLR B C9  1 
HETATM 7218 C C10 . CLR R 2 .   ? 166.882 232.365 207.511 1.00 92.66  ? 806 CLR B C10 1 
HETATM 7219 C C11 . CLR R 2 .   ? 166.018 233.816 205.560 1.00 94.61  ? 806 CLR B C11 1 
HETATM 7220 C C12 . CLR R 2 .   ? 165.189 233.869 204.273 1.00 93.14  ? 806 CLR B C12 1 
HETATM 7221 C C13 . CLR R 2 .   ? 165.701 232.870 203.235 1.00 95.36  ? 806 CLR B C13 1 
HETATM 7222 C C14 . CLR R 2 .   ? 165.711 231.485 203.906 1.00 93.50  ? 806 CLR B C14 1 
HETATM 7223 C C15 . CLR R 2 .   ? 165.993 230.517 202.764 1.00 89.88  ? 806 CLR B C15 1 
HETATM 7224 C C16 . CLR R 2 .   ? 165.300 231.178 201.557 1.00 90.17  ? 806 CLR B C16 1 
HETATM 7225 C C17 . CLR R 2 .   ? 164.760 232.552 202.046 1.00 91.64  ? 806 CLR B C17 1 
HETATM 7226 C C18 . CLR R 2 .   ? 167.082 233.283 202.716 1.00 93.60  ? 806 CLR B C18 1 
HETATM 7227 C C19 . CLR R 2 .   ? 168.321 232.869 207.324 1.00 91.21  ? 806 CLR B C19 1 
HETATM 7228 C C20 . CLR R 2 .   ? 164.573 233.589 200.922 1.00 92.84  ? 806 CLR B C20 1 
HETATM 7229 C C21 . CLR R 2 .   ? 163.125 234.058 200.795 1.00 93.48  ? 806 CLR B C21 1 
HETATM 7230 C C22 . CLR R 2 .   ? 165.118 233.067 199.579 1.00 90.06  ? 806 CLR B C22 1 
HETATM 7231 C C23 . CLR R 2 .   ? 164.098 232.625 198.530 1.00 90.98  ? 806 CLR B C23 1 
HETATM 7232 C C24 . CLR R 2 .   ? 163.991 233.602 197.362 1.00 92.19  ? 806 CLR B C24 1 
HETATM 7233 C C25 . CLR R 2 .   ? 165.310 233.971 196.681 1.00 89.32  ? 806 CLR B C25 1 
HETATM 7234 C C26 . CLR R 2 .   ? 165.971 232.730 196.089 1.00 90.83  ? 806 CLR B C26 1 
HETATM 7235 C C27 . CLR R 2 .   ? 165.119 235.029 195.598 1.00 90.23  ? 806 CLR B C27 1 
HETATM 7236 O O1  . CLR R 2 .   ? 166.974 231.467 211.741 1.00 91.09  ? 806 CLR B O1  1 
HETATM 7237 C C1  . PLM S 4 .   ? 189.446 188.403 206.581 1.00 53.99  ? 807 PLM B C1  1 
HETATM 7238 O O1  . PLM S 4 .   ? 189.572 188.510 207.831 1.00 55.90  ? 807 PLM B O1  1 
HETATM 7239 O O2  . PLM S 4 .   ? 188.903 189.201 205.769 1.00 51.31  ? 807 PLM B O2  1 
HETATM 7240 C C2  . PLM S 4 .   ? 190.056 187.090 205.976 1.00 52.10  ? 807 PLM B C2  1 
HETATM 7241 C C3  . PLM S 4 .   ? 189.747 186.840 204.498 1.00 48.87  ? 807 PLM B C3  1 
HETATM 7242 C C4  . PLM S 4 .   ? 190.605 185.739 203.856 1.00 48.11  ? 807 PLM B C4  1 
HETATM 7243 C C5  . PLM S 4 .   ? 190.329 185.536 202.359 1.00 48.71  ? 807 PLM B C5  1 
HETATM 7244 C C6  . PLM S 4 .   ? 191.572 185.670 201.466 1.00 48.88  ? 807 PLM B C6  1 
HETATM 7245 C C7  . PLM S 4 .   ? 191.539 186.893 200.540 1.00 51.47  ? 807 PLM B C7  1 
HETATM 7246 C C8  . PLM S 4 .   ? 192.826 187.099 199.734 1.00 50.43  ? 807 PLM B C8  1 
HETATM 7247 C C9  . PLM S 4 .   ? 192.757 188.278 198.756 1.00 51.49  ? 807 PLM B C9  1 
HETATM 7248 C CA  . PLM S 4 .   ? 194.036 188.478 197.935 1.00 51.19  ? 807 PLM B CA  1 
HETATM 7249 C CB  . PLM S 4 .   ? 194.317 187.344 196.942 1.00 53.33  ? 807 PLM B CB  1 
HETATM 7250 C CC  . PLM S 4 .   ? 195.622 187.525 196.154 1.00 51.61  ? 807 PLM B CC  1 
HETATM 7251 C CD  . PLM S 4 .   ? 195.505 187.131 194.677 1.00 49.19  ? 807 PLM B CD  1 
HETATM 7252 C CE  . PLM S 4 .   ? 194.441 187.928 193.910 1.00 54.62  ? 807 PLM B CE  1 
HETATM 7253 C CF  . PLM S 4 .   ? 194.258 187.474 192.456 1.00 55.98  ? 807 PLM B CF  1 
HETATM 7254 C CG  . PLM S 4 .   ? 193.189 188.271 191.699 1.00 53.32  ? 807 PLM B CG  1 
HETATM 7255 C C1  . ACD T 5 .   ? 182.193 211.478 167.889 1.00 83.66  ? 808 ACD B C1  1 
HETATM 7256 C C2  . ACD T 5 .   ? 183.676 211.771 168.186 1.00 83.96  ? 808 ACD B C2  1 
HETATM 7257 C C3  . ACD T 5 .   ? 183.957 212.777 169.289 1.00 86.00  ? 808 ACD B C3  1 
HETATM 7258 C C4  . ACD T 5 .   ? 183.491 212.280 170.660 1.00 82.09  ? 808 ACD B C4  1 
HETATM 7259 C C5  . ACD T 5 .   ? 184.209 212.952 171.787 1.00 78.49  ? 808 ACD B C5  1 
HETATM 7260 C C6  . ACD T 5 .   ? 184.911 212.381 172.764 1.00 78.35  ? 808 ACD B C6  1 
HETATM 7261 C C7  . ACD T 5 .   ? 185.628 213.064 173.892 1.00 78.99  ? 808 ACD B C7  1 
HETATM 7262 C C8  . ACD T 5 .   ? 184.843 212.928 175.166 1.00 78.65  ? 808 ACD B C8  1 
HETATM 7263 C C9  . ACD T 5 .   ? 185.314 212.755 176.399 1.00 79.01  ? 808 ACD B C9  1 
HETATM 7264 C C10 . ACD T 5 .   ? 184.515 212.621 177.664 1.00 73.64  ? 808 ACD B C10 1 
HETATM 7265 C C11 . ACD T 5 .   ? 184.963 213.632 178.680 1.00 75.68  ? 808 ACD B C11 1 
HETATM 7266 C C12 . ACD T 5 .   ? 185.517 213.386 179.865 1.00 77.05  ? 808 ACD B C12 1 
HETATM 7267 C C13 . ACD T 5 .   ? 185.817 212.036 180.448 1.00 81.27  ? 808 ACD B C13 1 
HETATM 7268 C C14 . ACD T 5 .   ? 185.753 212.071 181.949 1.00 78.13  ? 808 ACD B C14 1 
HETATM 7269 C C15 . ACD T 5 .   ? 186.153 213.042 182.768 1.00 74.76  ? 808 ACD B C15 1 
HETATM 7270 C C16 . ACD T 5 .   ? 186.084 213.057 184.262 1.00 76.54  ? 808 ACD B C16 1 
HETATM 7271 C C17 . ACD T 5 .   ? 185.886 214.463 184.831 1.00 81.18  ? 808 ACD B C17 1 
HETATM 7272 C C18 . ACD T 5 .   ? 185.869 214.472 186.354 1.00 82.79  ? 808 ACD B C18 1 
HETATM 7273 C C19 . ACD T 5 .   ? 186.118 215.849 186.957 1.00 81.62  ? 808 ACD B C19 1 
HETATM 7274 C C20 . ACD T 5 .   ? 186.427 215.784 188.446 1.00 79.54  ? 808 ACD B C20 1 
HETATM 7275 O O1  . ACD T 5 .   ? 181.911 210.385 167.361 1.00 83.89  ? 808 ACD B O1  1 
HETATM 7276 O O2  . ACD T 5 .   ? 181.382 212.376 168.203 1.00 81.68  ? 808 ACD B O2  1 
HETATM 7277 O O   . HOH U 6 .   ? 229.783 177.964 207.010 1.00 33.04  ? 901 HOH A O   1 
HETATM 7278 O O   . HOH U 6 .   ? 224.130 173.557 200.324 1.00 22.01  ? 902 HOH A O   1 
HETATM 7279 O O   . HOH U 6 .   ? 228.022 174.525 208.485 1.00 61.91  ? 903 HOH A O   1 
HETATM 7280 O O   . HOH V 6 .   ? 169.948 220.514 200.324 1.00 37.87  ? 901 HOH B O   1 
HETATM 7281 O O   . HOH V 6 .   ? 164.336 216.160 206.981 1.00 34.88  ? 902 HOH B O   1 
HETATM 7282 O O   . HOH V 6 .   ? 166.068 219.560 208.499 1.00 58.17  ? 903 HOH B O   1 
# 
