data_9INE
# 
_entry.id   9INE 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9INE         pdb_00009ine 10.2210/pdb9ine/pdb 
WWPDB D_1300049168 ?            ?                   
EMDB  EMD-60704    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9INE 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-06 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'cryo-EM structure of human XPR1-KIDINS220-1-432 in closed state' 
_pdbx_database_related.db_id          EMD-60704 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yinyuxin@hsc.pku.edu.cn 
_pdbx_contact_author.name_first         Yuxin 
_pdbx_contact_author.name_last          Yin 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4102-0043 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zuo, P.'   1 0000-0002-5631-9534 
'Liang, L.' 2 0000-0002-3115-2563 
'Yin, Y.'   3 0000-0003-4102-0043 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                2879 
_citation.page_last                 2879 
_citation.title                     
'Synergistic activation of the human phosphate exporter XPR1 by KIDINS220 and inositol pyrophosphate.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-58200-y 
_citation.pdbx_database_id_PubMed   40128258 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zuo, P.'   1 0000-0002-5631-9534 
primary 'Wang, W.'  2 0000-0001-7258-0356 
primary 'Dai, Z.'   3 0000-0002-4005-1297 
primary 'Zheng, J.' 4 ?                   
primary 'Yu, S.'    5 0009-0002-2665-8882 
primary 'Wang, G.'  6 0000-0002-4884-2990 
primary 'Yin, Y.'   7 ?                   
primary 'Liang, L.' 8 0000-0002-3115-2563 
primary 'Yin, Y.'   9 0000-0003-3646-8548 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Solute carrier family 53 member 1'          82673.992 2  ? ? ? ? 
2 non-polymer syn CHOLESTEROL                                  386.654   14 ? ? ? ? 
3 non-polymer syn 1,2-Distearoyl-sn-glycerophosphoethanolamine 748.065   6  ? ? ? ? 
4 non-polymer syn 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE    510.708   2  ? ? ? ? 
5 non-polymer syn 'PALMITIC ACID'                              256.424   2  ? ? ? ? 
6 non-polymer syn 'ARACHIDONIC ACID'                           304.467   2  ? ? ? ? 
7 water       nat water                                        18.015    8  ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Phosphate exporter SLC53A1,Protein SYG1 homolog,Xenotropic and polytropic murine leukemia virus receptor X3,X-receptor,Xenotropic and polytropic retrovirus receptor 1
;
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANTSRENLYFQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANTSRENLYFQ
;
_entity_poly.pdbx_strand_id                 B,A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 CHOLESTEROL                                  CLR 
3 1,2-Distearoyl-sn-glycerophosphoethanolamine 3PE 
4 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE    LPE 
5 'PALMITIC ACID'                              PLM 
6 'ARACHIDONIC ACID'                           ACD 
7 water                                        HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   PHE n 
1 4   ALA n 
1 5   GLU n 
1 6   HIS n 
1 7   LEU n 
1 8   SER n 
1 9   ALA n 
1 10  HIS n 
1 11  ILE n 
1 12  THR n 
1 13  PRO n 
1 14  GLU n 
1 15  TRP n 
1 16  ARG n 
1 17  LYS n 
1 18  GLN n 
1 19  TYR n 
1 20  ILE n 
1 21  GLN n 
1 22  TYR n 
1 23  GLU n 
1 24  ALA n 
1 25  PHE n 
1 26  LYS n 
1 27  ASP n 
1 28  MET n 
1 29  LEU n 
1 30  TYR n 
1 31  SER n 
1 32  ALA n 
1 33  GLN n 
1 34  ASP n 
1 35  GLN n 
1 36  ALA n 
1 37  PRO n 
1 38  SER n 
1 39  VAL n 
1 40  GLU n 
1 41  VAL n 
1 42  THR n 
1 43  ASP n 
1 44  GLU n 
1 45  ASP n 
1 46  THR n 
1 47  VAL n 
1 48  LYS n 
1 49  ARG n 
1 50  TYR n 
1 51  PHE n 
1 52  ALA n 
1 53  LYS n 
1 54  PHE n 
1 55  GLU n 
1 56  GLU n 
1 57  LYS n 
1 58  PHE n 
1 59  PHE n 
1 60  GLN n 
1 61  THR n 
1 62  CYS n 
1 63  GLU n 
1 64  LYS n 
1 65  GLU n 
1 66  LEU n 
1 67  ALA n 
1 68  LYS n 
1 69  ILE n 
1 70  ASN n 
1 71  THR n 
1 72  PHE n 
1 73  TYR n 
1 74  SER n 
1 75  GLU n 
1 76  LYS n 
1 77  LEU n 
1 78  ALA n 
1 79  GLU n 
1 80  ALA n 
1 81  GLN n 
1 82  ARG n 
1 83  ARG n 
1 84  PHE n 
1 85  ALA n 
1 86  THR n 
1 87  LEU n 
1 88  GLN n 
1 89  ASN n 
1 90  GLU n 
1 91  LEU n 
1 92  GLN n 
1 93  SER n 
1 94  SER n 
1 95  LEU n 
1 96  ASP n 
1 97  ALA n 
1 98  GLN n 
1 99  LYS n 
1 100 GLU n 
1 101 SER n 
1 102 THR n 
1 103 GLY n 
1 104 VAL n 
1 105 THR n 
1 106 THR n 
1 107 LEU n 
1 108 ARG n 
1 109 GLN n 
1 110 ARG n 
1 111 ARG n 
1 112 LYS n 
1 113 PRO n 
1 114 VAL n 
1 115 PHE n 
1 116 HIS n 
1 117 LEU n 
1 118 SER n 
1 119 HIS n 
1 120 GLU n 
1 121 GLU n 
1 122 ARG n 
1 123 VAL n 
1 124 GLN n 
1 125 HIS n 
1 126 ARG n 
1 127 ASN n 
1 128 ILE n 
1 129 LYS n 
1 130 ASP n 
1 131 LEU n 
1 132 LYS n 
1 133 LEU n 
1 134 ALA n 
1 135 PHE n 
1 136 SER n 
1 137 GLU n 
1 138 PHE n 
1 139 TYR n 
1 140 LEU n 
1 141 SER n 
1 142 LEU n 
1 143 ILE n 
1 144 LEU n 
1 145 LEU n 
1 146 GLN n 
1 147 ASN n 
1 148 TYR n 
1 149 GLN n 
1 150 ASN n 
1 151 LEU n 
1 152 ASN n 
1 153 PHE n 
1 154 THR n 
1 155 GLY n 
1 156 PHE n 
1 157 ARG n 
1 158 LYS n 
1 159 ILE n 
1 160 LEU n 
1 161 LYS n 
1 162 LYS n 
1 163 HIS n 
1 164 ASP n 
1 165 LYS n 
1 166 ILE n 
1 167 LEU n 
1 168 GLU n 
1 169 THR n 
1 170 SER n 
1 171 ARG n 
1 172 GLY n 
1 173 ALA n 
1 174 ASP n 
1 175 TRP n 
1 176 ARG n 
1 177 VAL n 
1 178 ALA n 
1 179 HIS n 
1 180 VAL n 
1 181 GLU n 
1 182 VAL n 
1 183 ALA n 
1 184 PRO n 
1 185 PHE n 
1 186 TYR n 
1 187 THR n 
1 188 CYS n 
1 189 LYS n 
1 190 LYS n 
1 191 ILE n 
1 192 ASN n 
1 193 GLN n 
1 194 LEU n 
1 195 ILE n 
1 196 SER n 
1 197 GLU n 
1 198 THR n 
1 199 GLU n 
1 200 ALA n 
1 201 VAL n 
1 202 VAL n 
1 203 THR n 
1 204 ASN n 
1 205 GLU n 
1 206 LEU n 
1 207 GLU n 
1 208 ASP n 
1 209 GLY n 
1 210 ASP n 
1 211 ARG n 
1 212 GLN n 
1 213 LYS n 
1 214 ALA n 
1 215 MET n 
1 216 LYS n 
1 217 ARG n 
1 218 LEU n 
1 219 ARG n 
1 220 VAL n 
1 221 PRO n 
1 222 PRO n 
1 223 LEU n 
1 224 GLY n 
1 225 ALA n 
1 226 ALA n 
1 227 GLN n 
1 228 PRO n 
1 229 ALA n 
1 230 PRO n 
1 231 ALA n 
1 232 TRP n 
1 233 THR n 
1 234 THR n 
1 235 PHE n 
1 236 ARG n 
1 237 VAL n 
1 238 GLY n 
1 239 LEU n 
1 240 PHE n 
1 241 CYS n 
1 242 GLY n 
1 243 ILE n 
1 244 PHE n 
1 245 ILE n 
1 246 VAL n 
1 247 LEU n 
1 248 ASN n 
1 249 ILE n 
1 250 THR n 
1 251 LEU n 
1 252 VAL n 
1 253 LEU n 
1 254 ALA n 
1 255 ALA n 
1 256 VAL n 
1 257 PHE n 
1 258 LYS n 
1 259 LEU n 
1 260 GLU n 
1 261 THR n 
1 262 ASP n 
1 263 ARG n 
1 264 SER n 
1 265 ILE n 
1 266 TRP n 
1 267 PRO n 
1 268 LEU n 
1 269 ILE n 
1 270 ARG n 
1 271 ILE n 
1 272 TYR n 
1 273 ARG n 
1 274 GLY n 
1 275 GLY n 
1 276 PHE n 
1 277 LEU n 
1 278 LEU n 
1 279 ILE n 
1 280 GLU n 
1 281 PHE n 
1 282 LEU n 
1 283 PHE n 
1 284 LEU n 
1 285 LEU n 
1 286 GLY n 
1 287 ILE n 
1 288 ASN n 
1 289 THR n 
1 290 TYR n 
1 291 GLY n 
1 292 TRP n 
1 293 ARG n 
1 294 GLN n 
1 295 ALA n 
1 296 GLY n 
1 297 VAL n 
1 298 ASN n 
1 299 HIS n 
1 300 VAL n 
1 301 LEU n 
1 302 ILE n 
1 303 PHE n 
1 304 GLU n 
1 305 LEU n 
1 306 ASN n 
1 307 PRO n 
1 308 ARG n 
1 309 SER n 
1 310 ASN n 
1 311 LEU n 
1 312 SER n 
1 313 HIS n 
1 314 GLN n 
1 315 HIS n 
1 316 LEU n 
1 317 PHE n 
1 318 GLU n 
1 319 ILE n 
1 320 ALA n 
1 321 GLY n 
1 322 PHE n 
1 323 LEU n 
1 324 GLY n 
1 325 ILE n 
1 326 LEU n 
1 327 TRP n 
1 328 CYS n 
1 329 LEU n 
1 330 SER n 
1 331 LEU n 
1 332 LEU n 
1 333 ALA n 
1 334 CYS n 
1 335 PHE n 
1 336 PHE n 
1 337 ALA n 
1 338 PRO n 
1 339 ILE n 
1 340 SER n 
1 341 VAL n 
1 342 ILE n 
1 343 PRO n 
1 344 THR n 
1 345 TYR n 
1 346 VAL n 
1 347 TYR n 
1 348 PRO n 
1 349 LEU n 
1 350 ALA n 
1 351 LEU n 
1 352 TYR n 
1 353 GLY n 
1 354 PHE n 
1 355 MET n 
1 356 VAL n 
1 357 PHE n 
1 358 PHE n 
1 359 LEU n 
1 360 ILE n 
1 361 ASN n 
1 362 PRO n 
1 363 THR n 
1 364 LYS n 
1 365 THR n 
1 366 PHE n 
1 367 TYR n 
1 368 TYR n 
1 369 LYS n 
1 370 SER n 
1 371 ARG n 
1 372 PHE n 
1 373 TRP n 
1 374 LEU n 
1 375 LEU n 
1 376 LYS n 
1 377 LEU n 
1 378 LEU n 
1 379 PHE n 
1 380 ARG n 
1 381 VAL n 
1 382 PHE n 
1 383 THR n 
1 384 ALA n 
1 385 PRO n 
1 386 PHE n 
1 387 HIS n 
1 388 LYS n 
1 389 VAL n 
1 390 GLY n 
1 391 PHE n 
1 392 ALA n 
1 393 ASP n 
1 394 PHE n 
1 395 TRP n 
1 396 LEU n 
1 397 ALA n 
1 398 ASP n 
1 399 GLN n 
1 400 LEU n 
1 401 ASN n 
1 402 SER n 
1 403 LEU n 
1 404 SER n 
1 405 VAL n 
1 406 ILE n 
1 407 LEU n 
1 408 MET n 
1 409 ASP n 
1 410 LEU n 
1 411 GLU n 
1 412 TYR n 
1 413 MET n 
1 414 ILE n 
1 415 CYS n 
1 416 PHE n 
1 417 TYR n 
1 418 SER n 
1 419 LEU n 
1 420 GLU n 
1 421 LEU n 
1 422 LYS n 
1 423 TRP n 
1 424 ASP n 
1 425 GLU n 
1 426 SER n 
1 427 LYS n 
1 428 GLY n 
1 429 LEU n 
1 430 LEU n 
1 431 PRO n 
1 432 ASN n 
1 433 ASN n 
1 434 SER n 
1 435 GLU n 
1 436 GLU n 
1 437 SER n 
1 438 GLY n 
1 439 ILE n 
1 440 CYS n 
1 441 HIS n 
1 442 LYS n 
1 443 TYR n 
1 444 THR n 
1 445 TYR n 
1 446 GLY n 
1 447 VAL n 
1 448 ARG n 
1 449 ALA n 
1 450 ILE n 
1 451 VAL n 
1 452 GLN n 
1 453 CYS n 
1 454 ILE n 
1 455 PRO n 
1 456 ALA n 
1 457 TRP n 
1 458 LEU n 
1 459 ARG n 
1 460 PHE n 
1 461 ILE n 
1 462 GLN n 
1 463 CYS n 
1 464 LEU n 
1 465 ARG n 
1 466 ARG n 
1 467 TYR n 
1 468 ARG n 
1 469 ASP n 
1 470 THR n 
1 471 LYS n 
1 472 ARG n 
1 473 ALA n 
1 474 PHE n 
1 475 PRO n 
1 476 HIS n 
1 477 LEU n 
1 478 VAL n 
1 479 ASN n 
1 480 ALA n 
1 481 GLY n 
1 482 LYS n 
1 483 TYR n 
1 484 SER n 
1 485 THR n 
1 486 THR n 
1 487 PHE n 
1 488 PHE n 
1 489 MET n 
1 490 VAL n 
1 491 THR n 
1 492 PHE n 
1 493 ALA n 
1 494 ALA n 
1 495 LEU n 
1 496 TYR n 
1 497 SER n 
1 498 THR n 
1 499 HIS n 
1 500 LYS n 
1 501 GLU n 
1 502 ARG n 
1 503 GLY n 
1 504 HIS n 
1 505 SER n 
1 506 ASP n 
1 507 THR n 
1 508 MET n 
1 509 VAL n 
1 510 PHE n 
1 511 PHE n 
1 512 TYR n 
1 513 LEU n 
1 514 TRP n 
1 515 ILE n 
1 516 VAL n 
1 517 PHE n 
1 518 TYR n 
1 519 ILE n 
1 520 ILE n 
1 521 SER n 
1 522 SER n 
1 523 CYS n 
1 524 TYR n 
1 525 THR n 
1 526 LEU n 
1 527 ILE n 
1 528 TRP n 
1 529 ASP n 
1 530 LEU n 
1 531 LYS n 
1 532 MET n 
1 533 ASP n 
1 534 TRP n 
1 535 GLY n 
1 536 LEU n 
1 537 PHE n 
1 538 ASP n 
1 539 LYS n 
1 540 ASN n 
1 541 ALA n 
1 542 GLY n 
1 543 GLU n 
1 544 ASN n 
1 545 THR n 
1 546 PHE n 
1 547 LEU n 
1 548 ARG n 
1 549 GLU n 
1 550 GLU n 
1 551 ILE n 
1 552 VAL n 
1 553 TYR n 
1 554 PRO n 
1 555 GLN n 
1 556 LYS n 
1 557 ALA n 
1 558 TYR n 
1 559 TYR n 
1 560 TYR n 
1 561 CYS n 
1 562 ALA n 
1 563 ILE n 
1 564 ILE n 
1 565 GLU n 
1 566 ASP n 
1 567 VAL n 
1 568 ILE n 
1 569 LEU n 
1 570 ARG n 
1 571 PHE n 
1 572 ALA n 
1 573 TRP n 
1 574 THR n 
1 575 ILE n 
1 576 GLN n 
1 577 ILE n 
1 578 SER n 
1 579 ILE n 
1 580 THR n 
1 581 SER n 
1 582 THR n 
1 583 THR n 
1 584 LEU n 
1 585 LEU n 
1 586 PRO n 
1 587 HIS n 
1 588 SER n 
1 589 GLY n 
1 590 ASP n 
1 591 ILE n 
1 592 ILE n 
1 593 ALA n 
1 594 THR n 
1 595 VAL n 
1 596 PHE n 
1 597 ALA n 
1 598 PRO n 
1 599 LEU n 
1 600 GLU n 
1 601 VAL n 
1 602 PHE n 
1 603 ARG n 
1 604 ARG n 
1 605 PHE n 
1 606 VAL n 
1 607 TRP n 
1 608 ASN n 
1 609 PHE n 
1 610 PHE n 
1 611 ARG n 
1 612 LEU n 
1 613 GLU n 
1 614 ASN n 
1 615 GLU n 
1 616 HIS n 
1 617 LEU n 
1 618 ASN n 
1 619 ASN n 
1 620 CYS n 
1 621 GLY n 
1 622 GLU n 
1 623 PHE n 
1 624 ARG n 
1 625 ALA n 
1 626 VAL n 
1 627 ARG n 
1 628 ASP n 
1 629 ILE n 
1 630 SER n 
1 631 VAL n 
1 632 ALA n 
1 633 PRO n 
1 634 LEU n 
1 635 ASN n 
1 636 ALA n 
1 637 ASP n 
1 638 ASP n 
1 639 GLN n 
1 640 THR n 
1 641 LEU n 
1 642 LEU n 
1 643 GLU n 
1 644 GLN n 
1 645 MET n 
1 646 MET n 
1 647 ASP n 
1 648 GLN n 
1 649 ASP n 
1 650 ASP n 
1 651 GLY n 
1 652 VAL n 
1 653 ARG n 
1 654 ASN n 
1 655 ARG n 
1 656 GLN n 
1 657 LYS n 
1 658 ASN n 
1 659 ARG n 
1 660 SER n 
1 661 TRP n 
1 662 LYS n 
1 663 TYR n 
1 664 ASN n 
1 665 GLN n 
1 666 SER n 
1 667 ILE n 
1 668 SER n 
1 669 LEU n 
1 670 ARG n 
1 671 ARG n 
1 672 PRO n 
1 673 ARG n 
1 674 LEU n 
1 675 ALA n 
1 676 SER n 
1 677 GLN n 
1 678 SER n 
1 679 LYS n 
1 680 ALA n 
1 681 ARG n 
1 682 ASP n 
1 683 THR n 
1 684 LYS n 
1 685 VAL n 
1 686 LEU n 
1 687 ILE n 
1 688 GLU n 
1 689 ASP n 
1 690 THR n 
1 691 ASP n 
1 692 ASP n 
1 693 GLU n 
1 694 ALA n 
1 695 ASN n 
1 696 THR n 
1 697 SER n 
1 698 ARG n 
1 699 GLU n 
1 700 ASN n 
1 701 LEU n 
1 702 TYR n 
1 703 PHE n 
1 704 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   704 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'XPR1, SLC53A1, SYG1, X3' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
3PE non-polymer         . 1,2-Distearoyl-sn-glycerophosphoethanolamine 
'3-SN-PHOSPHATIDYLETHANOLAMINE; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE' 'C41 H82 N O8 P'   748.065 
ACD non-polymer         . 'ARACHIDONIC ACID'                           ? 'C20 H32 O2'       304.467 
ALA 'L-peptide linking' y ALANINE                                      ? 'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                                     ? 'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                                   ? 'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                              ? 'C4 H7 N O4'       133.103 
CLR non-polymer         . CHOLESTEROL                                  ? 'C27 H46 O'        386.654 
CYS 'L-peptide linking' y CYSTEINE                                     ? 'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE                                    ? 'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                              ? 'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                                      ? 'C2 H5 N O2'       75.067  
HIS 'L-peptide linking' y HISTIDINE                                    ? 'C6 H10 N3 O2 1'   156.162 
HOH non-polymer         . WATER                                        ? 'H2 O'             18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                   ? 'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                                      ? 'C6 H13 N O2'      131.173 
LPE non-polymer         . 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE    LPC-ETHER 'C26 H57 N O6 P 1' 510.708 
LYS 'L-peptide linking' y LYSINE                                       ? 'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                                   ? 'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                ? 'C9 H11 N O2'      165.189 
PLM non-polymer         . 'PALMITIC ACID'                              ? 'C16 H32 O2'       256.424 
PRO 'L-peptide linking' y PROLINE                                      ? 'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                                       ? 'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                                    ? 'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                   ? 'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                                     ? 'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                                       ? 'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   B . n 
A 1 2   LYS 2   2   ?   ?   ?   B . n 
A 1 3   PHE 3   3   ?   ?   ?   B . n 
A 1 4   ALA 4   4   ?   ?   ?   B . n 
A 1 5   GLU 5   5   ?   ?   ?   B . n 
A 1 6   HIS 6   6   ?   ?   ?   B . n 
A 1 7   LEU 7   7   ?   ?   ?   B . n 
A 1 8   SER 8   8   ?   ?   ?   B . n 
A 1 9   ALA 9   9   ?   ?   ?   B . n 
A 1 10  HIS 10  10  ?   ?   ?   B . n 
A 1 11  ILE 11  11  ?   ?   ?   B . n 
A 1 12  THR 12  12  ?   ?   ?   B . n 
A 1 13  PRO 13  13  ?   ?   ?   B . n 
A 1 14  GLU 14  14  ?   ?   ?   B . n 
A 1 15  TRP 15  15  ?   ?   ?   B . n 
A 1 16  ARG 16  16  ?   ?   ?   B . n 
A 1 17  LYS 17  17  ?   ?   ?   B . n 
A 1 18  GLN 18  18  ?   ?   ?   B . n 
A 1 19  TYR 19  19  ?   ?   ?   B . n 
A 1 20  ILE 20  20  ?   ?   ?   B . n 
A 1 21  GLN 21  21  ?   ?   ?   B . n 
A 1 22  TYR 22  22  ?   ?   ?   B . n 
A 1 23  GLU 23  23  ?   ?   ?   B . n 
A 1 24  ALA 24  24  ?   ?   ?   B . n 
A 1 25  PHE 25  25  ?   ?   ?   B . n 
A 1 26  LYS 26  26  ?   ?   ?   B . n 
A 1 27  ASP 27  27  ?   ?   ?   B . n 
A 1 28  MET 28  28  ?   ?   ?   B . n 
A 1 29  LEU 29  29  ?   ?   ?   B . n 
A 1 30  TYR 30  30  ?   ?   ?   B . n 
A 1 31  SER 31  31  ?   ?   ?   B . n 
A 1 32  ALA 32  32  ?   ?   ?   B . n 
A 1 33  GLN 33  33  ?   ?   ?   B . n 
A 1 34  ASP 34  34  ?   ?   ?   B . n 
A 1 35  GLN 35  35  ?   ?   ?   B . n 
A 1 36  ALA 36  36  ?   ?   ?   B . n 
A 1 37  PRO 37  37  ?   ?   ?   B . n 
A 1 38  SER 38  38  ?   ?   ?   B . n 
A 1 39  VAL 39  39  ?   ?   ?   B . n 
A 1 40  GLU 40  40  ?   ?   ?   B . n 
A 1 41  VAL 41  41  ?   ?   ?   B . n 
A 1 42  THR 42  42  ?   ?   ?   B . n 
A 1 43  ASP 43  43  ?   ?   ?   B . n 
A 1 44  GLU 44  44  ?   ?   ?   B . n 
A 1 45  ASP 45  45  ?   ?   ?   B . n 
A 1 46  THR 46  46  ?   ?   ?   B . n 
A 1 47  VAL 47  47  ?   ?   ?   B . n 
A 1 48  LYS 48  48  ?   ?   ?   B . n 
A 1 49  ARG 49  49  ?   ?   ?   B . n 
A 1 50  TYR 50  50  ?   ?   ?   B . n 
A 1 51  PHE 51  51  ?   ?   ?   B . n 
A 1 52  ALA 52  52  ?   ?   ?   B . n 
A 1 53  LYS 53  53  ?   ?   ?   B . n 
A 1 54  PHE 54  54  ?   ?   ?   B . n 
A 1 55  GLU 55  55  ?   ?   ?   B . n 
A 1 56  GLU 56  56  ?   ?   ?   B . n 
A 1 57  LYS 57  57  ?   ?   ?   B . n 
A 1 58  PHE 58  58  ?   ?   ?   B . n 
A 1 59  PHE 59  59  ?   ?   ?   B . n 
A 1 60  GLN 60  60  ?   ?   ?   B . n 
A 1 61  THR 61  61  ?   ?   ?   B . n 
A 1 62  CYS 62  62  ?   ?   ?   B . n 
A 1 63  GLU 63  63  ?   ?   ?   B . n 
A 1 64  LYS 64  64  ?   ?   ?   B . n 
A 1 65  GLU 65  65  ?   ?   ?   B . n 
A 1 66  LEU 66  66  ?   ?   ?   B . n 
A 1 67  ALA 67  67  ?   ?   ?   B . n 
A 1 68  LYS 68  68  ?   ?   ?   B . n 
A 1 69  ILE 69  69  ?   ?   ?   B . n 
A 1 70  ASN 70  70  ?   ?   ?   B . n 
A 1 71  THR 71  71  ?   ?   ?   B . n 
A 1 72  PHE 72  72  ?   ?   ?   B . n 
A 1 73  TYR 73  73  ?   ?   ?   B . n 
A 1 74  SER 74  74  ?   ?   ?   B . n 
A 1 75  GLU 75  75  ?   ?   ?   B . n 
A 1 76  LYS 76  76  ?   ?   ?   B . n 
A 1 77  LEU 77  77  ?   ?   ?   B . n 
A 1 78  ALA 78  78  ?   ?   ?   B . n 
A 1 79  GLU 79  79  ?   ?   ?   B . n 
A 1 80  ALA 80  80  ?   ?   ?   B . n 
A 1 81  GLN 81  81  ?   ?   ?   B . n 
A 1 82  ARG 82  82  ?   ?   ?   B . n 
A 1 83  ARG 83  83  ?   ?   ?   B . n 
A 1 84  PHE 84  84  ?   ?   ?   B . n 
A 1 85  ALA 85  85  ?   ?   ?   B . n 
A 1 86  THR 86  86  ?   ?   ?   B . n 
A 1 87  LEU 87  87  ?   ?   ?   B . n 
A 1 88  GLN 88  88  ?   ?   ?   B . n 
A 1 89  ASN 89  89  ?   ?   ?   B . n 
A 1 90  GLU 90  90  ?   ?   ?   B . n 
A 1 91  LEU 91  91  ?   ?   ?   B . n 
A 1 92  GLN 92  92  ?   ?   ?   B . n 
A 1 93  SER 93  93  ?   ?   ?   B . n 
A 1 94  SER 94  94  ?   ?   ?   B . n 
A 1 95  LEU 95  95  ?   ?   ?   B . n 
A 1 96  ASP 96  96  ?   ?   ?   B . n 
A 1 97  ALA 97  97  ?   ?   ?   B . n 
A 1 98  GLN 98  98  ?   ?   ?   B . n 
A 1 99  LYS 99  99  ?   ?   ?   B . n 
A 1 100 GLU 100 100 ?   ?   ?   B . n 
A 1 101 SER 101 101 ?   ?   ?   B . n 
A 1 102 THR 102 102 ?   ?   ?   B . n 
A 1 103 GLY 103 103 ?   ?   ?   B . n 
A 1 104 VAL 104 104 ?   ?   ?   B . n 
A 1 105 THR 105 105 ?   ?   ?   B . n 
A 1 106 THR 106 106 ?   ?   ?   B . n 
A 1 107 LEU 107 107 ?   ?   ?   B . n 
A 1 108 ARG 108 108 ?   ?   ?   B . n 
A 1 109 GLN 109 109 ?   ?   ?   B . n 
A 1 110 ARG 110 110 ?   ?   ?   B . n 
A 1 111 ARG 111 111 ?   ?   ?   B . n 
A 1 112 LYS 112 112 ?   ?   ?   B . n 
A 1 113 PRO 113 113 ?   ?   ?   B . n 
A 1 114 VAL 114 114 ?   ?   ?   B . n 
A 1 115 PHE 115 115 ?   ?   ?   B . n 
A 1 116 HIS 116 116 ?   ?   ?   B . n 
A 1 117 LEU 117 117 ?   ?   ?   B . n 
A 1 118 SER 118 118 ?   ?   ?   B . n 
A 1 119 HIS 119 119 ?   ?   ?   B . n 
A 1 120 GLU 120 120 ?   ?   ?   B . n 
A 1 121 GLU 121 121 ?   ?   ?   B . n 
A 1 122 ARG 122 122 ?   ?   ?   B . n 
A 1 123 VAL 123 123 ?   ?   ?   B . n 
A 1 124 GLN 124 124 ?   ?   ?   B . n 
A 1 125 HIS 125 125 ?   ?   ?   B . n 
A 1 126 ARG 126 126 ?   ?   ?   B . n 
A 1 127 ASN 127 127 ?   ?   ?   B . n 
A 1 128 ILE 128 128 ?   ?   ?   B . n 
A 1 129 LYS 129 129 ?   ?   ?   B . n 
A 1 130 ASP 130 130 ?   ?   ?   B . n 
A 1 131 LEU 131 131 ?   ?   ?   B . n 
A 1 132 LYS 132 132 ?   ?   ?   B . n 
A 1 133 LEU 133 133 ?   ?   ?   B . n 
A 1 134 ALA 134 134 ?   ?   ?   B . n 
A 1 135 PHE 135 135 ?   ?   ?   B . n 
A 1 136 SER 136 136 ?   ?   ?   B . n 
A 1 137 GLU 137 137 ?   ?   ?   B . n 
A 1 138 PHE 138 138 ?   ?   ?   B . n 
A 1 139 TYR 139 139 ?   ?   ?   B . n 
A 1 140 LEU 140 140 ?   ?   ?   B . n 
A 1 141 SER 141 141 ?   ?   ?   B . n 
A 1 142 LEU 142 142 ?   ?   ?   B . n 
A 1 143 ILE 143 143 ?   ?   ?   B . n 
A 1 144 LEU 144 144 ?   ?   ?   B . n 
A 1 145 LEU 145 145 ?   ?   ?   B . n 
A 1 146 GLN 146 146 ?   ?   ?   B . n 
A 1 147 ASN 147 147 ?   ?   ?   B . n 
A 1 148 TYR 148 148 ?   ?   ?   B . n 
A 1 149 GLN 149 149 ?   ?   ?   B . n 
A 1 150 ASN 150 150 ?   ?   ?   B . n 
A 1 151 LEU 151 151 ?   ?   ?   B . n 
A 1 152 ASN 152 152 ?   ?   ?   B . n 
A 1 153 PHE 153 153 ?   ?   ?   B . n 
A 1 154 THR 154 154 ?   ?   ?   B . n 
A 1 155 GLY 155 155 ?   ?   ?   B . n 
A 1 156 PHE 156 156 ?   ?   ?   B . n 
A 1 157 ARG 157 157 ?   ?   ?   B . n 
A 1 158 LYS 158 158 ?   ?   ?   B . n 
A 1 159 ILE 159 159 ?   ?   ?   B . n 
A 1 160 LEU 160 160 ?   ?   ?   B . n 
A 1 161 LYS 161 161 ?   ?   ?   B . n 
A 1 162 LYS 162 162 ?   ?   ?   B . n 
A 1 163 HIS 163 163 ?   ?   ?   B . n 
A 1 164 ASP 164 164 ?   ?   ?   B . n 
A 1 165 LYS 165 165 ?   ?   ?   B . n 
A 1 166 ILE 166 166 ?   ?   ?   B . n 
A 1 167 LEU 167 167 ?   ?   ?   B . n 
A 1 168 GLU 168 168 ?   ?   ?   B . n 
A 1 169 THR 169 169 ?   ?   ?   B . n 
A 1 170 SER 170 170 ?   ?   ?   B . n 
A 1 171 ARG 171 171 ?   ?   ?   B . n 
A 1 172 GLY 172 172 ?   ?   ?   B . n 
A 1 173 ALA 173 173 ?   ?   ?   B . n 
A 1 174 ASP 174 174 ?   ?   ?   B . n 
A 1 175 TRP 175 175 ?   ?   ?   B . n 
A 1 176 ARG 176 176 ?   ?   ?   B . n 
A 1 177 VAL 177 177 ?   ?   ?   B . n 
A 1 178 ALA 178 178 ?   ?   ?   B . n 
A 1 179 HIS 179 179 ?   ?   ?   B . n 
A 1 180 VAL 180 180 ?   ?   ?   B . n 
A 1 181 GLU 181 181 ?   ?   ?   B . n 
A 1 182 VAL 182 182 ?   ?   ?   B . n 
A 1 183 ALA 183 183 ?   ?   ?   B . n 
A 1 184 PRO 184 184 ?   ?   ?   B . n 
A 1 185 PHE 185 185 ?   ?   ?   B . n 
A 1 186 TYR 186 186 ?   ?   ?   B . n 
A 1 187 THR 187 187 ?   ?   ?   B . n 
A 1 188 CYS 188 188 ?   ?   ?   B . n 
A 1 189 LYS 189 189 ?   ?   ?   B . n 
A 1 190 LYS 190 190 ?   ?   ?   B . n 
A 1 191 ILE 191 191 ?   ?   ?   B . n 
A 1 192 ASN 192 192 ?   ?   ?   B . n 
A 1 193 GLN 193 193 ?   ?   ?   B . n 
A 1 194 LEU 194 194 ?   ?   ?   B . n 
A 1 195 ILE 195 195 ?   ?   ?   B . n 
A 1 196 SER 196 196 ?   ?   ?   B . n 
A 1 197 GLU 197 197 ?   ?   ?   B . n 
A 1 198 THR 198 198 ?   ?   ?   B . n 
A 1 199 GLU 199 199 ?   ?   ?   B . n 
A 1 200 ALA 200 200 ?   ?   ?   B . n 
A 1 201 VAL 201 201 ?   ?   ?   B . n 
A 1 202 VAL 202 202 ?   ?   ?   B . n 
A 1 203 THR 203 203 ?   ?   ?   B . n 
A 1 204 ASN 204 204 ?   ?   ?   B . n 
A 1 205 GLU 205 205 ?   ?   ?   B . n 
A 1 206 LEU 206 206 ?   ?   ?   B . n 
A 1 207 GLU 207 207 ?   ?   ?   B . n 
A 1 208 ASP 208 208 ?   ?   ?   B . n 
A 1 209 GLY 209 209 ?   ?   ?   B . n 
A 1 210 ASP 210 210 ?   ?   ?   B . n 
A 1 211 ARG 211 211 ?   ?   ?   B . n 
A 1 212 GLN 212 212 ?   ?   ?   B . n 
A 1 213 LYS 213 213 ?   ?   ?   B . n 
A 1 214 ALA 214 214 ?   ?   ?   B . n 
A 1 215 MET 215 215 ?   ?   ?   B . n 
A 1 216 LYS 216 216 ?   ?   ?   B . n 
A 1 217 ARG 217 217 ?   ?   ?   B . n 
A 1 218 LEU 218 218 ?   ?   ?   B . n 
A 1 219 ARG 219 219 ?   ?   ?   B . n 
A 1 220 VAL 220 220 ?   ?   ?   B . n 
A 1 221 PRO 221 221 ?   ?   ?   B . n 
A 1 222 PRO 222 222 ?   ?   ?   B . n 
A 1 223 LEU 223 223 ?   ?   ?   B . n 
A 1 224 GLY 224 224 ?   ?   ?   B . n 
A 1 225 ALA 225 225 ?   ?   ?   B . n 
A 1 226 ALA 226 226 226 ALA ALA B . n 
A 1 227 GLN 227 227 227 GLN GLN B . n 
A 1 228 PRO 228 228 228 PRO PRO B . n 
A 1 229 ALA 229 229 229 ALA ALA B . n 
A 1 230 PRO 230 230 230 PRO PRO B . n 
A 1 231 ALA 231 231 231 ALA ALA B . n 
A 1 232 TRP 232 232 232 TRP TRP B . n 
A 1 233 THR 233 233 233 THR THR B . n 
A 1 234 THR 234 234 234 THR THR B . n 
A 1 235 PHE 235 235 235 PHE PHE B . n 
A 1 236 ARG 236 236 236 ARG ARG B . n 
A 1 237 VAL 237 237 237 VAL VAL B . n 
A 1 238 GLY 238 238 238 GLY GLY B . n 
A 1 239 LEU 239 239 239 LEU LEU B . n 
A 1 240 PHE 240 240 240 PHE PHE B . n 
A 1 241 CYS 241 241 241 CYS CYS B . n 
A 1 242 GLY 242 242 242 GLY GLY B . n 
A 1 243 ILE 243 243 243 ILE ILE B . n 
A 1 244 PHE 244 244 244 PHE PHE B . n 
A 1 245 ILE 245 245 245 ILE ILE B . n 
A 1 246 VAL 246 246 246 VAL VAL B . n 
A 1 247 LEU 247 247 247 LEU LEU B . n 
A 1 248 ASN 248 248 248 ASN ASN B . n 
A 1 249 ILE 249 249 249 ILE ILE B . n 
A 1 250 THR 250 250 250 THR THR B . n 
A 1 251 LEU 251 251 251 LEU LEU B . n 
A 1 252 VAL 252 252 252 VAL VAL B . n 
A 1 253 LEU 253 253 253 LEU LEU B . n 
A 1 254 ALA 254 254 254 ALA ALA B . n 
A 1 255 ALA 255 255 255 ALA ALA B . n 
A 1 256 VAL 256 256 256 VAL VAL B . n 
A 1 257 PHE 257 257 257 PHE PHE B . n 
A 1 258 LYS 258 258 258 LYS LYS B . n 
A 1 259 LEU 259 259 259 LEU LEU B . n 
A 1 260 GLU 260 260 260 GLU GLU B . n 
A 1 261 THR 261 261 261 THR THR B . n 
A 1 262 ASP 262 262 262 ASP ASP B . n 
A 1 263 ARG 263 263 263 ARG ARG B . n 
A 1 264 SER 264 264 264 SER SER B . n 
A 1 265 ILE 265 265 265 ILE ILE B . n 
A 1 266 TRP 266 266 266 TRP TRP B . n 
A 1 267 PRO 267 267 267 PRO PRO B . n 
A 1 268 LEU 268 268 268 LEU LEU B . n 
A 1 269 ILE 269 269 269 ILE ILE B . n 
A 1 270 ARG 270 270 270 ARG ARG B . n 
A 1 271 ILE 271 271 271 ILE ILE B . n 
A 1 272 TYR 272 272 272 TYR TYR B . n 
A 1 273 ARG 273 273 273 ARG ARG B . n 
A 1 274 GLY 274 274 274 GLY GLY B . n 
A 1 275 GLY 275 275 275 GLY GLY B . n 
A 1 276 PHE 276 276 276 PHE PHE B . n 
A 1 277 LEU 277 277 277 LEU LEU B . n 
A 1 278 LEU 278 278 278 LEU LEU B . n 
A 1 279 ILE 279 279 279 ILE ILE B . n 
A 1 280 GLU 280 280 280 GLU GLU B . n 
A 1 281 PHE 281 281 281 PHE PHE B . n 
A 1 282 LEU 282 282 282 LEU LEU B . n 
A 1 283 PHE 283 283 283 PHE PHE B . n 
A 1 284 LEU 284 284 284 LEU LEU B . n 
A 1 285 LEU 285 285 285 LEU LEU B . n 
A 1 286 GLY 286 286 286 GLY GLY B . n 
A 1 287 ILE 287 287 287 ILE ILE B . n 
A 1 288 ASN 288 288 288 ASN ASN B . n 
A 1 289 THR 289 289 289 THR THR B . n 
A 1 290 TYR 290 290 290 TYR TYR B . n 
A 1 291 GLY 291 291 291 GLY GLY B . n 
A 1 292 TRP 292 292 292 TRP TRP B . n 
A 1 293 ARG 293 293 293 ARG ARG B . n 
A 1 294 GLN 294 294 294 GLN GLN B . n 
A 1 295 ALA 295 295 295 ALA ALA B . n 
A 1 296 GLY 296 296 296 GLY GLY B . n 
A 1 297 VAL 297 297 297 VAL VAL B . n 
A 1 298 ASN 298 298 298 ASN ASN B . n 
A 1 299 HIS 299 299 299 HIS HIS B . n 
A 1 300 VAL 300 300 300 VAL VAL B . n 
A 1 301 LEU 301 301 301 LEU LEU B . n 
A 1 302 ILE 302 302 302 ILE ILE B . n 
A 1 303 PHE 303 303 303 PHE PHE B . n 
A 1 304 GLU 304 304 304 GLU GLU B . n 
A 1 305 LEU 305 305 305 LEU LEU B . n 
A 1 306 ASN 306 306 306 ASN ASN B . n 
A 1 307 PRO 307 307 307 PRO PRO B . n 
A 1 308 ARG 308 308 308 ARG ARG B . n 
A 1 309 SER 309 309 309 SER SER B . n 
A 1 310 ASN 310 310 310 ASN ASN B . n 
A 1 311 LEU 311 311 311 LEU LEU B . n 
A 1 312 SER 312 312 312 SER SER B . n 
A 1 313 HIS 313 313 313 HIS HIS B . n 
A 1 314 GLN 314 314 314 GLN GLN B . n 
A 1 315 HIS 315 315 315 HIS HIS B . n 
A 1 316 LEU 316 316 316 LEU LEU B . n 
A 1 317 PHE 317 317 317 PHE PHE B . n 
A 1 318 GLU 318 318 318 GLU GLU B . n 
A 1 319 ILE 319 319 319 ILE ILE B . n 
A 1 320 ALA 320 320 320 ALA ALA B . n 
A 1 321 GLY 321 321 321 GLY GLY B . n 
A 1 322 PHE 322 322 322 PHE PHE B . n 
A 1 323 LEU 323 323 323 LEU LEU B . n 
A 1 324 GLY 324 324 324 GLY GLY B . n 
A 1 325 ILE 325 325 325 ILE ILE B . n 
A 1 326 LEU 326 326 326 LEU LEU B . n 
A 1 327 TRP 327 327 327 TRP TRP B . n 
A 1 328 CYS 328 328 328 CYS CYS B . n 
A 1 329 LEU 329 329 329 LEU LEU B . n 
A 1 330 SER 330 330 330 SER SER B . n 
A 1 331 LEU 331 331 331 LEU LEU B . n 
A 1 332 LEU 332 332 332 LEU LEU B . n 
A 1 333 ALA 333 333 333 ALA ALA B . n 
A 1 334 CYS 334 334 334 CYS CYS B . n 
A 1 335 PHE 335 335 335 PHE PHE B . n 
A 1 336 PHE 336 336 336 PHE PHE B . n 
A 1 337 ALA 337 337 337 ALA ALA B . n 
A 1 338 PRO 338 338 338 PRO PRO B . n 
A 1 339 ILE 339 339 339 ILE ILE B . n 
A 1 340 SER 340 340 340 SER SER B . n 
A 1 341 VAL 341 341 341 VAL VAL B . n 
A 1 342 ILE 342 342 342 ILE ILE B . n 
A 1 343 PRO 343 343 343 PRO PRO B . n 
A 1 344 THR 344 344 344 THR THR B . n 
A 1 345 TYR 345 345 345 TYR TYR B . n 
A 1 346 VAL 346 346 346 VAL VAL B . n 
A 1 347 TYR 347 347 347 TYR TYR B . n 
A 1 348 PRO 348 348 348 PRO PRO B . n 
A 1 349 LEU 349 349 349 LEU LEU B . n 
A 1 350 ALA 350 350 350 ALA ALA B . n 
A 1 351 LEU 351 351 351 LEU LEU B . n 
A 1 352 TYR 352 352 352 TYR TYR B . n 
A 1 353 GLY 353 353 353 GLY GLY B . n 
A 1 354 PHE 354 354 354 PHE PHE B . n 
A 1 355 MET 355 355 355 MET MET B . n 
A 1 356 VAL 356 356 356 VAL VAL B . n 
A 1 357 PHE 357 357 357 PHE PHE B . n 
A 1 358 PHE 358 358 358 PHE PHE B . n 
A 1 359 LEU 359 359 359 LEU LEU B . n 
A 1 360 ILE 360 360 360 ILE ILE B . n 
A 1 361 ASN 361 361 361 ASN ASN B . n 
A 1 362 PRO 362 362 362 PRO PRO B . n 
A 1 363 THR 363 363 363 THR THR B . n 
A 1 364 LYS 364 364 364 LYS LYS B . n 
A 1 365 THR 365 365 365 THR THR B . n 
A 1 366 PHE 366 366 366 PHE PHE B . n 
A 1 367 TYR 367 367 367 TYR TYR B . n 
A 1 368 TYR 368 368 368 TYR TYR B . n 
A 1 369 LYS 369 369 369 LYS LYS B . n 
A 1 370 SER 370 370 370 SER SER B . n 
A 1 371 ARG 371 371 371 ARG ARG B . n 
A 1 372 PHE 372 372 372 PHE PHE B . n 
A 1 373 TRP 373 373 373 TRP TRP B . n 
A 1 374 LEU 374 374 374 LEU LEU B . n 
A 1 375 LEU 375 375 375 LEU LEU B . n 
A 1 376 LYS 376 376 376 LYS LYS B . n 
A 1 377 LEU 377 377 377 LEU LEU B . n 
A 1 378 LEU 378 378 378 LEU LEU B . n 
A 1 379 PHE 379 379 379 PHE PHE B . n 
A 1 380 ARG 380 380 380 ARG ARG B . n 
A 1 381 VAL 381 381 381 VAL VAL B . n 
A 1 382 PHE 382 382 382 PHE PHE B . n 
A 1 383 THR 383 383 383 THR THR B . n 
A 1 384 ALA 384 384 384 ALA ALA B . n 
A 1 385 PRO 385 385 385 PRO PRO B . n 
A 1 386 PHE 386 386 386 PHE PHE B . n 
A 1 387 HIS 387 387 387 HIS HIS B . n 
A 1 388 LYS 388 388 388 LYS LYS B . n 
A 1 389 VAL 389 389 389 VAL VAL B . n 
A 1 390 GLY 390 390 390 GLY GLY B . n 
A 1 391 PHE 391 391 391 PHE PHE B . n 
A 1 392 ALA 392 392 392 ALA ALA B . n 
A 1 393 ASP 393 393 393 ASP ASP B . n 
A 1 394 PHE 394 394 394 PHE PHE B . n 
A 1 395 TRP 395 395 395 TRP TRP B . n 
A 1 396 LEU 396 396 396 LEU LEU B . n 
A 1 397 ALA 397 397 397 ALA ALA B . n 
A 1 398 ASP 398 398 398 ASP ASP B . n 
A 1 399 GLN 399 399 399 GLN GLN B . n 
A 1 400 LEU 400 400 400 LEU LEU B . n 
A 1 401 ASN 401 401 401 ASN ASN B . n 
A 1 402 SER 402 402 402 SER SER B . n 
A 1 403 LEU 403 403 403 LEU LEU B . n 
A 1 404 SER 404 404 404 SER SER B . n 
A 1 405 VAL 405 405 405 VAL VAL B . n 
A 1 406 ILE 406 406 406 ILE ILE B . n 
A 1 407 LEU 407 407 407 LEU LEU B . n 
A 1 408 MET 408 408 408 MET MET B . n 
A 1 409 ASP 409 409 409 ASP ASP B . n 
A 1 410 LEU 410 410 410 LEU LEU B . n 
A 1 411 GLU 411 411 411 GLU GLU B . n 
A 1 412 TYR 412 412 412 TYR TYR B . n 
A 1 413 MET 413 413 413 MET MET B . n 
A 1 414 ILE 414 414 414 ILE ILE B . n 
A 1 415 CYS 415 415 415 CYS CYS B . n 
A 1 416 PHE 416 416 416 PHE PHE B . n 
A 1 417 TYR 417 417 417 TYR TYR B . n 
A 1 418 SER 418 418 418 SER SER B . n 
A 1 419 LEU 419 419 419 LEU LEU B . n 
A 1 420 GLU 420 420 420 GLU GLU B . n 
A 1 421 LEU 421 421 421 LEU LEU B . n 
A 1 422 LYS 422 422 422 LYS LYS B . n 
A 1 423 TRP 423 423 423 TRP TRP B . n 
A 1 424 ASP 424 424 424 ASP ASP B . n 
A 1 425 GLU 425 425 425 GLU GLU B . n 
A 1 426 SER 426 426 426 SER SER B . n 
A 1 427 LYS 427 427 427 LYS LYS B . n 
A 1 428 GLY 428 428 428 GLY GLY B . n 
A 1 429 LEU 429 429 429 LEU LEU B . n 
A 1 430 LEU 430 430 430 LEU LEU B . n 
A 1 431 PRO 431 431 431 PRO PRO B . n 
A 1 432 ASN 432 432 432 ASN ASN B . n 
A 1 433 ASN 433 433 433 ASN ASN B . n 
A 1 434 SER 434 434 434 SER SER B . n 
A 1 435 GLU 435 435 435 GLU GLU B . n 
A 1 436 GLU 436 436 436 GLU GLU B . n 
A 1 437 SER 437 437 437 SER SER B . n 
A 1 438 GLY 438 438 438 GLY GLY B . n 
A 1 439 ILE 439 439 439 ILE ILE B . n 
A 1 440 CYS 440 440 440 CYS CYS B . n 
A 1 441 HIS 441 441 441 HIS HIS B . n 
A 1 442 LYS 442 442 442 LYS LYS B . n 
A 1 443 TYR 443 443 443 TYR TYR B . n 
A 1 444 THR 444 444 444 THR THR B . n 
A 1 445 TYR 445 445 445 TYR TYR B . n 
A 1 446 GLY 446 446 446 GLY GLY B . n 
A 1 447 VAL 447 447 447 VAL VAL B . n 
A 1 448 ARG 448 448 448 ARG ARG B . n 
A 1 449 ALA 449 449 449 ALA ALA B . n 
A 1 450 ILE 450 450 450 ILE ILE B . n 
A 1 451 VAL 451 451 451 VAL VAL B . n 
A 1 452 GLN 452 452 452 GLN GLN B . n 
A 1 453 CYS 453 453 453 CYS CYS B . n 
A 1 454 ILE 454 454 454 ILE ILE B . n 
A 1 455 PRO 455 455 455 PRO PRO B . n 
A 1 456 ALA 456 456 456 ALA ALA B . n 
A 1 457 TRP 457 457 457 TRP TRP B . n 
A 1 458 LEU 458 458 458 LEU LEU B . n 
A 1 459 ARG 459 459 459 ARG ARG B . n 
A 1 460 PHE 460 460 460 PHE PHE B . n 
A 1 461 ILE 461 461 461 ILE ILE B . n 
A 1 462 GLN 462 462 462 GLN GLN B . n 
A 1 463 CYS 463 463 463 CYS CYS B . n 
A 1 464 LEU 464 464 464 LEU LEU B . n 
A 1 465 ARG 465 465 465 ARG ARG B . n 
A 1 466 ARG 466 466 466 ARG ARG B . n 
A 1 467 TYR 467 467 467 TYR TYR B . n 
A 1 468 ARG 468 468 468 ARG ARG B . n 
A 1 469 ASP 469 469 469 ASP ASP B . n 
A 1 470 THR 470 470 470 THR THR B . n 
A 1 471 LYS 471 471 471 LYS LYS B . n 
A 1 472 ARG 472 472 472 ARG ARG B . n 
A 1 473 ALA 473 473 473 ALA ALA B . n 
A 1 474 PHE 474 474 474 PHE PHE B . n 
A 1 475 PRO 475 475 475 PRO PRO B . n 
A 1 476 HIS 476 476 476 HIS HIS B . n 
A 1 477 LEU 477 477 477 LEU LEU B . n 
A 1 478 VAL 478 478 478 VAL VAL B . n 
A 1 479 ASN 479 479 479 ASN ASN B . n 
A 1 480 ALA 480 480 480 ALA ALA B . n 
A 1 481 GLY 481 481 481 GLY GLY B . n 
A 1 482 LYS 482 482 482 LYS LYS B . n 
A 1 483 TYR 483 483 483 TYR TYR B . n 
A 1 484 SER 484 484 484 SER SER B . n 
A 1 485 THR 485 485 485 THR THR B . n 
A 1 486 THR 486 486 486 THR THR B . n 
A 1 487 PHE 487 487 487 PHE PHE B . n 
A 1 488 PHE 488 488 488 PHE PHE B . n 
A 1 489 MET 489 489 489 MET MET B . n 
A 1 490 VAL 490 490 490 VAL VAL B . n 
A 1 491 THR 491 491 491 THR THR B . n 
A 1 492 PHE 492 492 492 PHE PHE B . n 
A 1 493 ALA 493 493 493 ALA ALA B . n 
A 1 494 ALA 494 494 494 ALA ALA B . n 
A 1 495 LEU 495 495 495 LEU LEU B . n 
A 1 496 TYR 496 496 496 TYR TYR B . n 
A 1 497 SER 497 497 497 SER SER B . n 
A 1 498 THR 498 498 498 THR THR B . n 
A 1 499 HIS 499 499 499 HIS HIS B . n 
A 1 500 LYS 500 500 500 LYS LYS B . n 
A 1 501 GLU 501 501 501 GLU GLU B . n 
A 1 502 ARG 502 502 502 ARG ARG B . n 
A 1 503 GLY 503 503 503 GLY GLY B . n 
A 1 504 HIS 504 504 504 HIS HIS B . n 
A 1 505 SER 505 505 505 SER SER B . n 
A 1 506 ASP 506 506 506 ASP ASP B . n 
A 1 507 THR 507 507 507 THR THR B . n 
A 1 508 MET 508 508 508 MET MET B . n 
A 1 509 VAL 509 509 509 VAL VAL B . n 
A 1 510 PHE 510 510 510 PHE PHE B . n 
A 1 511 PHE 511 511 511 PHE PHE B . n 
A 1 512 TYR 512 512 512 TYR TYR B . n 
A 1 513 LEU 513 513 513 LEU LEU B . n 
A 1 514 TRP 514 514 514 TRP TRP B . n 
A 1 515 ILE 515 515 515 ILE ILE B . n 
A 1 516 VAL 516 516 516 VAL VAL B . n 
A 1 517 PHE 517 517 517 PHE PHE B . n 
A 1 518 TYR 518 518 518 TYR TYR B . n 
A 1 519 ILE 519 519 519 ILE ILE B . n 
A 1 520 ILE 520 520 520 ILE ILE B . n 
A 1 521 SER 521 521 521 SER SER B . n 
A 1 522 SER 522 522 522 SER SER B . n 
A 1 523 CYS 523 523 523 CYS CYS B . n 
A 1 524 TYR 524 524 524 TYR TYR B . n 
A 1 525 THR 525 525 525 THR THR B . n 
A 1 526 LEU 526 526 526 LEU LEU B . n 
A 1 527 ILE 527 527 527 ILE ILE B . n 
A 1 528 TRP 528 528 528 TRP TRP B . n 
A 1 529 ASP 529 529 529 ASP ASP B . n 
A 1 530 LEU 530 530 530 LEU LEU B . n 
A 1 531 LYS 531 531 531 LYS LYS B . n 
A 1 532 MET 532 532 532 MET MET B . n 
A 1 533 ASP 533 533 533 ASP ASP B . n 
A 1 534 TRP 534 534 534 TRP TRP B . n 
A 1 535 GLY 535 535 535 GLY GLY B . n 
A 1 536 LEU 536 536 536 LEU LEU B . n 
A 1 537 PHE 537 537 537 PHE PHE B . n 
A 1 538 ASP 538 538 538 ASP ASP B . n 
A 1 539 LYS 539 539 539 LYS LYS B . n 
A 1 540 ASN 540 540 540 ASN ASN B . n 
A 1 541 ALA 541 541 541 ALA ALA B . n 
A 1 542 GLY 542 542 542 GLY GLY B . n 
A 1 543 GLU 543 543 543 GLU GLU B . n 
A 1 544 ASN 544 544 544 ASN ASN B . n 
A 1 545 THR 545 545 545 THR THR B . n 
A 1 546 PHE 546 546 546 PHE PHE B . n 
A 1 547 LEU 547 547 547 LEU LEU B . n 
A 1 548 ARG 548 548 548 ARG ARG B . n 
A 1 549 GLU 549 549 549 GLU GLU B . n 
A 1 550 GLU 550 550 550 GLU GLU B . n 
A 1 551 ILE 551 551 551 ILE ILE B . n 
A 1 552 VAL 552 552 552 VAL VAL B . n 
A 1 553 TYR 553 553 553 TYR TYR B . n 
A 1 554 PRO 554 554 554 PRO PRO B . n 
A 1 555 GLN 555 555 555 GLN GLN B . n 
A 1 556 LYS 556 556 556 LYS LYS B . n 
A 1 557 ALA 557 557 557 ALA ALA B . n 
A 1 558 TYR 558 558 558 TYR TYR B . n 
A 1 559 TYR 559 559 559 TYR TYR B . n 
A 1 560 TYR 560 560 560 TYR TYR B . n 
A 1 561 CYS 561 561 561 CYS CYS B . n 
A 1 562 ALA 562 562 562 ALA ALA B . n 
A 1 563 ILE 563 563 563 ILE ILE B . n 
A 1 564 ILE 564 564 564 ILE ILE B . n 
A 1 565 GLU 565 565 565 GLU GLU B . n 
A 1 566 ASP 566 566 566 ASP ASP B . n 
A 1 567 VAL 567 567 567 VAL VAL B . n 
A 1 568 ILE 568 568 568 ILE ILE B . n 
A 1 569 LEU 569 569 569 LEU LEU B . n 
A 1 570 ARG 570 570 570 ARG ARG B . n 
A 1 571 PHE 571 571 571 PHE PHE B . n 
A 1 572 ALA 572 572 572 ALA ALA B . n 
A 1 573 TRP 573 573 573 TRP TRP B . n 
A 1 574 THR 574 574 574 THR THR B . n 
A 1 575 ILE 575 575 575 ILE ILE B . n 
A 1 576 GLN 576 576 576 GLN GLN B . n 
A 1 577 ILE 577 577 577 ILE ILE B . n 
A 1 578 SER 578 578 578 SER SER B . n 
A 1 579 ILE 579 579 579 ILE ILE B . n 
A 1 580 THR 580 580 580 THR THR B . n 
A 1 581 SER 581 581 581 SER SER B . n 
A 1 582 THR 582 582 582 THR THR B . n 
A 1 583 THR 583 583 583 THR THR B . n 
A 1 584 LEU 584 584 584 LEU LEU B . n 
A 1 585 LEU 585 585 585 LEU LEU B . n 
A 1 586 PRO 586 586 586 PRO PRO B . n 
A 1 587 HIS 587 587 587 HIS HIS B . n 
A 1 588 SER 588 588 588 SER SER B . n 
A 1 589 GLY 589 589 589 GLY GLY B . n 
A 1 590 ASP 590 590 590 ASP ASP B . n 
A 1 591 ILE 591 591 591 ILE ILE B . n 
A 1 592 ILE 592 592 592 ILE ILE B . n 
A 1 593 ALA 593 593 593 ALA ALA B . n 
A 1 594 THR 594 594 594 THR THR B . n 
A 1 595 VAL 595 595 595 VAL VAL B . n 
A 1 596 PHE 596 596 596 PHE PHE B . n 
A 1 597 ALA 597 597 597 ALA ALA B . n 
A 1 598 PRO 598 598 598 PRO PRO B . n 
A 1 599 LEU 599 599 599 LEU LEU B . n 
A 1 600 GLU 600 600 600 GLU GLU B . n 
A 1 601 VAL 601 601 601 VAL VAL B . n 
A 1 602 PHE 602 602 602 PHE PHE B . n 
A 1 603 ARG 603 603 603 ARG ARG B . n 
A 1 604 ARG 604 604 604 ARG ARG B . n 
A 1 605 PHE 605 605 605 PHE PHE B . n 
A 1 606 VAL 606 606 606 VAL VAL B . n 
A 1 607 TRP 607 607 607 TRP TRP B . n 
A 1 608 ASN 608 608 608 ASN ASN B . n 
A 1 609 PHE 609 609 609 PHE PHE B . n 
A 1 610 PHE 610 610 610 PHE PHE B . n 
A 1 611 ARG 611 611 611 ARG ARG B . n 
A 1 612 LEU 612 612 612 LEU LEU B . n 
A 1 613 GLU 613 613 613 GLU GLU B . n 
A 1 614 ASN 614 614 614 ASN ASN B . n 
A 1 615 GLU 615 615 615 GLU GLU B . n 
A 1 616 HIS 616 616 616 HIS HIS B . n 
A 1 617 LEU 617 617 617 LEU LEU B . n 
A 1 618 ASN 618 618 618 ASN ASN B . n 
A 1 619 ASN 619 619 619 ASN ASN B . n 
A 1 620 CYS 620 620 620 CYS CYS B . n 
A 1 621 GLY 621 621 621 GLY GLY B . n 
A 1 622 GLU 622 622 622 GLU GLU B . n 
A 1 623 PHE 623 623 623 PHE PHE B . n 
A 1 624 ARG 624 624 624 ARG ARG B . n 
A 1 625 ALA 625 625 625 ALA ALA B . n 
A 1 626 VAL 626 626 626 VAL VAL B . n 
A 1 627 ARG 627 627 ?   ?   ?   B . n 
A 1 628 ASP 628 628 ?   ?   ?   B . n 
A 1 629 ILE 629 629 ?   ?   ?   B . n 
A 1 630 SER 630 630 ?   ?   ?   B . n 
A 1 631 VAL 631 631 ?   ?   ?   B . n 
A 1 632 ALA 632 632 ?   ?   ?   B . n 
A 1 633 PRO 633 633 ?   ?   ?   B . n 
A 1 634 LEU 634 634 ?   ?   ?   B . n 
A 1 635 ASN 635 635 ?   ?   ?   B . n 
A 1 636 ALA 636 636 ?   ?   ?   B . n 
A 1 637 ASP 637 637 ?   ?   ?   B . n 
A 1 638 ASP 638 638 ?   ?   ?   B . n 
A 1 639 GLN 639 639 ?   ?   ?   B . n 
A 1 640 THR 640 640 ?   ?   ?   B . n 
A 1 641 LEU 641 641 ?   ?   ?   B . n 
A 1 642 LEU 642 642 ?   ?   ?   B . n 
A 1 643 GLU 643 643 ?   ?   ?   B . n 
A 1 644 GLN 644 644 ?   ?   ?   B . n 
A 1 645 MET 645 645 ?   ?   ?   B . n 
A 1 646 MET 646 646 ?   ?   ?   B . n 
A 1 647 ASP 647 647 ?   ?   ?   B . n 
A 1 648 GLN 648 648 ?   ?   ?   B . n 
A 1 649 ASP 649 649 ?   ?   ?   B . n 
A 1 650 ASP 650 650 ?   ?   ?   B . n 
A 1 651 GLY 651 651 ?   ?   ?   B . n 
A 1 652 VAL 652 652 ?   ?   ?   B . n 
A 1 653 ARG 653 653 ?   ?   ?   B . n 
A 1 654 ASN 654 654 ?   ?   ?   B . n 
A 1 655 ARG 655 655 ?   ?   ?   B . n 
A 1 656 GLN 656 656 ?   ?   ?   B . n 
A 1 657 LYS 657 657 ?   ?   ?   B . n 
A 1 658 ASN 658 658 ?   ?   ?   B . n 
A 1 659 ARG 659 659 ?   ?   ?   B . n 
A 1 660 SER 660 660 ?   ?   ?   B . n 
A 1 661 TRP 661 661 ?   ?   ?   B . n 
A 1 662 LYS 662 662 ?   ?   ?   B . n 
A 1 663 TYR 663 663 ?   ?   ?   B . n 
A 1 664 ASN 664 664 ?   ?   ?   B . n 
A 1 665 GLN 665 665 ?   ?   ?   B . n 
A 1 666 SER 666 666 ?   ?   ?   B . n 
A 1 667 ILE 667 667 ?   ?   ?   B . n 
A 1 668 SER 668 668 ?   ?   ?   B . n 
A 1 669 LEU 669 669 ?   ?   ?   B . n 
A 1 670 ARG 670 670 ?   ?   ?   B . n 
A 1 671 ARG 671 671 ?   ?   ?   B . n 
A 1 672 PRO 672 672 ?   ?   ?   B . n 
A 1 673 ARG 673 673 ?   ?   ?   B . n 
A 1 674 LEU 674 674 ?   ?   ?   B . n 
A 1 675 ALA 675 675 ?   ?   ?   B . n 
A 1 676 SER 676 676 ?   ?   ?   B . n 
A 1 677 GLN 677 677 ?   ?   ?   B . n 
A 1 678 SER 678 678 ?   ?   ?   B . n 
A 1 679 LYS 679 679 ?   ?   ?   B . n 
A 1 680 ALA 680 680 ?   ?   ?   B . n 
A 1 681 ARG 681 681 ?   ?   ?   B . n 
A 1 682 ASP 682 682 ?   ?   ?   B . n 
A 1 683 THR 683 683 ?   ?   ?   B . n 
A 1 684 LYS 684 684 ?   ?   ?   B . n 
A 1 685 VAL 685 685 ?   ?   ?   B . n 
A 1 686 LEU 686 686 ?   ?   ?   B . n 
A 1 687 ILE 687 687 ?   ?   ?   B . n 
A 1 688 GLU 688 688 ?   ?   ?   B . n 
A 1 689 ASP 689 689 ?   ?   ?   B . n 
A 1 690 THR 690 690 ?   ?   ?   B . n 
A 1 691 ASP 691 691 ?   ?   ?   B . n 
A 1 692 ASP 692 692 ?   ?   ?   B . n 
A 1 693 GLU 693 693 ?   ?   ?   B . n 
A 1 694 ALA 694 694 ?   ?   ?   B . n 
A 1 695 ASN 695 695 ?   ?   ?   B . n 
A 1 696 THR 696 696 ?   ?   ?   B . n 
A 1 697 SER 697 697 ?   ?   ?   B . n 
A 1 698 ARG 698 698 ?   ?   ?   B . n 
A 1 699 GLU 699 699 ?   ?   ?   B . n 
A 1 700 ASN 700 700 ?   ?   ?   B . n 
A 1 701 LEU 701 701 ?   ?   ?   B . n 
A 1 702 TYR 702 702 ?   ?   ?   B . n 
A 1 703 PHE 703 703 ?   ?   ?   B . n 
A 1 704 GLN 704 704 ?   ?   ?   B . n 
B 1 1   MET 1   1   ?   ?   ?   A . n 
B 1 2   LYS 2   2   ?   ?   ?   A . n 
B 1 3   PHE 3   3   ?   ?   ?   A . n 
B 1 4   ALA 4   4   ?   ?   ?   A . n 
B 1 5   GLU 5   5   ?   ?   ?   A . n 
B 1 6   HIS 6   6   ?   ?   ?   A . n 
B 1 7   LEU 7   7   ?   ?   ?   A . n 
B 1 8   SER 8   8   ?   ?   ?   A . n 
B 1 9   ALA 9   9   ?   ?   ?   A . n 
B 1 10  HIS 10  10  ?   ?   ?   A . n 
B 1 11  ILE 11  11  ?   ?   ?   A . n 
B 1 12  THR 12  12  ?   ?   ?   A . n 
B 1 13  PRO 13  13  ?   ?   ?   A . n 
B 1 14  GLU 14  14  ?   ?   ?   A . n 
B 1 15  TRP 15  15  ?   ?   ?   A . n 
B 1 16  ARG 16  16  ?   ?   ?   A . n 
B 1 17  LYS 17  17  ?   ?   ?   A . n 
B 1 18  GLN 18  18  ?   ?   ?   A . n 
B 1 19  TYR 19  19  ?   ?   ?   A . n 
B 1 20  ILE 20  20  ?   ?   ?   A . n 
B 1 21  GLN 21  21  ?   ?   ?   A . n 
B 1 22  TYR 22  22  ?   ?   ?   A . n 
B 1 23  GLU 23  23  ?   ?   ?   A . n 
B 1 24  ALA 24  24  ?   ?   ?   A . n 
B 1 25  PHE 25  25  ?   ?   ?   A . n 
B 1 26  LYS 26  26  ?   ?   ?   A . n 
B 1 27  ASP 27  27  ?   ?   ?   A . n 
B 1 28  MET 28  28  ?   ?   ?   A . n 
B 1 29  LEU 29  29  ?   ?   ?   A . n 
B 1 30  TYR 30  30  ?   ?   ?   A . n 
B 1 31  SER 31  31  ?   ?   ?   A . n 
B 1 32  ALA 32  32  ?   ?   ?   A . n 
B 1 33  GLN 33  33  ?   ?   ?   A . n 
B 1 34  ASP 34  34  ?   ?   ?   A . n 
B 1 35  GLN 35  35  ?   ?   ?   A . n 
B 1 36  ALA 36  36  ?   ?   ?   A . n 
B 1 37  PRO 37  37  ?   ?   ?   A . n 
B 1 38  SER 38  38  ?   ?   ?   A . n 
B 1 39  VAL 39  39  ?   ?   ?   A . n 
B 1 40  GLU 40  40  ?   ?   ?   A . n 
B 1 41  VAL 41  41  ?   ?   ?   A . n 
B 1 42  THR 42  42  ?   ?   ?   A . n 
B 1 43  ASP 43  43  ?   ?   ?   A . n 
B 1 44  GLU 44  44  ?   ?   ?   A . n 
B 1 45  ASP 45  45  ?   ?   ?   A . n 
B 1 46  THR 46  46  ?   ?   ?   A . n 
B 1 47  VAL 47  47  ?   ?   ?   A . n 
B 1 48  LYS 48  48  ?   ?   ?   A . n 
B 1 49  ARG 49  49  ?   ?   ?   A . n 
B 1 50  TYR 50  50  ?   ?   ?   A . n 
B 1 51  PHE 51  51  ?   ?   ?   A . n 
B 1 52  ALA 52  52  ?   ?   ?   A . n 
B 1 53  LYS 53  53  ?   ?   ?   A . n 
B 1 54  PHE 54  54  ?   ?   ?   A . n 
B 1 55  GLU 55  55  ?   ?   ?   A . n 
B 1 56  GLU 56  56  ?   ?   ?   A . n 
B 1 57  LYS 57  57  ?   ?   ?   A . n 
B 1 58  PHE 58  58  ?   ?   ?   A . n 
B 1 59  PHE 59  59  ?   ?   ?   A . n 
B 1 60  GLN 60  60  ?   ?   ?   A . n 
B 1 61  THR 61  61  ?   ?   ?   A . n 
B 1 62  CYS 62  62  ?   ?   ?   A . n 
B 1 63  GLU 63  63  ?   ?   ?   A . n 
B 1 64  LYS 64  64  ?   ?   ?   A . n 
B 1 65  GLU 65  65  ?   ?   ?   A . n 
B 1 66  LEU 66  66  ?   ?   ?   A . n 
B 1 67  ALA 67  67  ?   ?   ?   A . n 
B 1 68  LYS 68  68  ?   ?   ?   A . n 
B 1 69  ILE 69  69  ?   ?   ?   A . n 
B 1 70  ASN 70  70  ?   ?   ?   A . n 
B 1 71  THR 71  71  ?   ?   ?   A . n 
B 1 72  PHE 72  72  ?   ?   ?   A . n 
B 1 73  TYR 73  73  ?   ?   ?   A . n 
B 1 74  SER 74  74  ?   ?   ?   A . n 
B 1 75  GLU 75  75  ?   ?   ?   A . n 
B 1 76  LYS 76  76  ?   ?   ?   A . n 
B 1 77  LEU 77  77  ?   ?   ?   A . n 
B 1 78  ALA 78  78  ?   ?   ?   A . n 
B 1 79  GLU 79  79  ?   ?   ?   A . n 
B 1 80  ALA 80  80  ?   ?   ?   A . n 
B 1 81  GLN 81  81  ?   ?   ?   A . n 
B 1 82  ARG 82  82  ?   ?   ?   A . n 
B 1 83  ARG 83  83  ?   ?   ?   A . n 
B 1 84  PHE 84  84  ?   ?   ?   A . n 
B 1 85  ALA 85  85  ?   ?   ?   A . n 
B 1 86  THR 86  86  ?   ?   ?   A . n 
B 1 87  LEU 87  87  ?   ?   ?   A . n 
B 1 88  GLN 88  88  ?   ?   ?   A . n 
B 1 89  ASN 89  89  ?   ?   ?   A . n 
B 1 90  GLU 90  90  ?   ?   ?   A . n 
B 1 91  LEU 91  91  ?   ?   ?   A . n 
B 1 92  GLN 92  92  ?   ?   ?   A . n 
B 1 93  SER 93  93  ?   ?   ?   A . n 
B 1 94  SER 94  94  ?   ?   ?   A . n 
B 1 95  LEU 95  95  ?   ?   ?   A . n 
B 1 96  ASP 96  96  ?   ?   ?   A . n 
B 1 97  ALA 97  97  ?   ?   ?   A . n 
B 1 98  GLN 98  98  ?   ?   ?   A . n 
B 1 99  LYS 99  99  ?   ?   ?   A . n 
B 1 100 GLU 100 100 ?   ?   ?   A . n 
B 1 101 SER 101 101 ?   ?   ?   A . n 
B 1 102 THR 102 102 ?   ?   ?   A . n 
B 1 103 GLY 103 103 ?   ?   ?   A . n 
B 1 104 VAL 104 104 ?   ?   ?   A . n 
B 1 105 THR 105 105 ?   ?   ?   A . n 
B 1 106 THR 106 106 ?   ?   ?   A . n 
B 1 107 LEU 107 107 ?   ?   ?   A . n 
B 1 108 ARG 108 108 ?   ?   ?   A . n 
B 1 109 GLN 109 109 ?   ?   ?   A . n 
B 1 110 ARG 110 110 ?   ?   ?   A . n 
B 1 111 ARG 111 111 ?   ?   ?   A . n 
B 1 112 LYS 112 112 ?   ?   ?   A . n 
B 1 113 PRO 113 113 ?   ?   ?   A . n 
B 1 114 VAL 114 114 ?   ?   ?   A . n 
B 1 115 PHE 115 115 ?   ?   ?   A . n 
B 1 116 HIS 116 116 ?   ?   ?   A . n 
B 1 117 LEU 117 117 ?   ?   ?   A . n 
B 1 118 SER 118 118 ?   ?   ?   A . n 
B 1 119 HIS 119 119 ?   ?   ?   A . n 
B 1 120 GLU 120 120 ?   ?   ?   A . n 
B 1 121 GLU 121 121 ?   ?   ?   A . n 
B 1 122 ARG 122 122 ?   ?   ?   A . n 
B 1 123 VAL 123 123 ?   ?   ?   A . n 
B 1 124 GLN 124 124 ?   ?   ?   A . n 
B 1 125 HIS 125 125 ?   ?   ?   A . n 
B 1 126 ARG 126 126 ?   ?   ?   A . n 
B 1 127 ASN 127 127 ?   ?   ?   A . n 
B 1 128 ILE 128 128 ?   ?   ?   A . n 
B 1 129 LYS 129 129 ?   ?   ?   A . n 
B 1 130 ASP 130 130 ?   ?   ?   A . n 
B 1 131 LEU 131 131 ?   ?   ?   A . n 
B 1 132 LYS 132 132 ?   ?   ?   A . n 
B 1 133 LEU 133 133 ?   ?   ?   A . n 
B 1 134 ALA 134 134 ?   ?   ?   A . n 
B 1 135 PHE 135 135 ?   ?   ?   A . n 
B 1 136 SER 136 136 ?   ?   ?   A . n 
B 1 137 GLU 137 137 ?   ?   ?   A . n 
B 1 138 PHE 138 138 ?   ?   ?   A . n 
B 1 139 TYR 139 139 ?   ?   ?   A . n 
B 1 140 LEU 140 140 ?   ?   ?   A . n 
B 1 141 SER 141 141 ?   ?   ?   A . n 
B 1 142 LEU 142 142 ?   ?   ?   A . n 
B 1 143 ILE 143 143 ?   ?   ?   A . n 
B 1 144 LEU 144 144 ?   ?   ?   A . n 
B 1 145 LEU 145 145 ?   ?   ?   A . n 
B 1 146 GLN 146 146 ?   ?   ?   A . n 
B 1 147 ASN 147 147 ?   ?   ?   A . n 
B 1 148 TYR 148 148 ?   ?   ?   A . n 
B 1 149 GLN 149 149 ?   ?   ?   A . n 
B 1 150 ASN 150 150 ?   ?   ?   A . n 
B 1 151 LEU 151 151 ?   ?   ?   A . n 
B 1 152 ASN 152 152 ?   ?   ?   A . n 
B 1 153 PHE 153 153 ?   ?   ?   A . n 
B 1 154 THR 154 154 ?   ?   ?   A . n 
B 1 155 GLY 155 155 ?   ?   ?   A . n 
B 1 156 PHE 156 156 ?   ?   ?   A . n 
B 1 157 ARG 157 157 ?   ?   ?   A . n 
B 1 158 LYS 158 158 ?   ?   ?   A . n 
B 1 159 ILE 159 159 ?   ?   ?   A . n 
B 1 160 LEU 160 160 ?   ?   ?   A . n 
B 1 161 LYS 161 161 ?   ?   ?   A . n 
B 1 162 LYS 162 162 ?   ?   ?   A . n 
B 1 163 HIS 163 163 ?   ?   ?   A . n 
B 1 164 ASP 164 164 ?   ?   ?   A . n 
B 1 165 LYS 165 165 ?   ?   ?   A . n 
B 1 166 ILE 166 166 ?   ?   ?   A . n 
B 1 167 LEU 167 167 ?   ?   ?   A . n 
B 1 168 GLU 168 168 ?   ?   ?   A . n 
B 1 169 THR 169 169 ?   ?   ?   A . n 
B 1 170 SER 170 170 ?   ?   ?   A . n 
B 1 171 ARG 171 171 ?   ?   ?   A . n 
B 1 172 GLY 172 172 ?   ?   ?   A . n 
B 1 173 ALA 173 173 ?   ?   ?   A . n 
B 1 174 ASP 174 174 ?   ?   ?   A . n 
B 1 175 TRP 175 175 ?   ?   ?   A . n 
B 1 176 ARG 176 176 ?   ?   ?   A . n 
B 1 177 VAL 177 177 ?   ?   ?   A . n 
B 1 178 ALA 178 178 ?   ?   ?   A . n 
B 1 179 HIS 179 179 ?   ?   ?   A . n 
B 1 180 VAL 180 180 ?   ?   ?   A . n 
B 1 181 GLU 181 181 ?   ?   ?   A . n 
B 1 182 VAL 182 182 ?   ?   ?   A . n 
B 1 183 ALA 183 183 ?   ?   ?   A . n 
B 1 184 PRO 184 184 ?   ?   ?   A . n 
B 1 185 PHE 185 185 ?   ?   ?   A . n 
B 1 186 TYR 186 186 ?   ?   ?   A . n 
B 1 187 THR 187 187 ?   ?   ?   A . n 
B 1 188 CYS 188 188 ?   ?   ?   A . n 
B 1 189 LYS 189 189 ?   ?   ?   A . n 
B 1 190 LYS 190 190 ?   ?   ?   A . n 
B 1 191 ILE 191 191 ?   ?   ?   A . n 
B 1 192 ASN 192 192 ?   ?   ?   A . n 
B 1 193 GLN 193 193 ?   ?   ?   A . n 
B 1 194 LEU 194 194 ?   ?   ?   A . n 
B 1 195 ILE 195 195 ?   ?   ?   A . n 
B 1 196 SER 196 196 ?   ?   ?   A . n 
B 1 197 GLU 197 197 ?   ?   ?   A . n 
B 1 198 THR 198 198 ?   ?   ?   A . n 
B 1 199 GLU 199 199 ?   ?   ?   A . n 
B 1 200 ALA 200 200 ?   ?   ?   A . n 
B 1 201 VAL 201 201 ?   ?   ?   A . n 
B 1 202 VAL 202 202 ?   ?   ?   A . n 
B 1 203 THR 203 203 ?   ?   ?   A . n 
B 1 204 ASN 204 204 ?   ?   ?   A . n 
B 1 205 GLU 205 205 ?   ?   ?   A . n 
B 1 206 LEU 206 206 ?   ?   ?   A . n 
B 1 207 GLU 207 207 ?   ?   ?   A . n 
B 1 208 ASP 208 208 ?   ?   ?   A . n 
B 1 209 GLY 209 209 ?   ?   ?   A . n 
B 1 210 ASP 210 210 ?   ?   ?   A . n 
B 1 211 ARG 211 211 ?   ?   ?   A . n 
B 1 212 GLN 212 212 ?   ?   ?   A . n 
B 1 213 LYS 213 213 ?   ?   ?   A . n 
B 1 214 ALA 214 214 ?   ?   ?   A . n 
B 1 215 MET 215 215 ?   ?   ?   A . n 
B 1 216 LYS 216 216 ?   ?   ?   A . n 
B 1 217 ARG 217 217 ?   ?   ?   A . n 
B 1 218 LEU 218 218 ?   ?   ?   A . n 
B 1 219 ARG 219 219 ?   ?   ?   A . n 
B 1 220 VAL 220 220 ?   ?   ?   A . n 
B 1 221 PRO 221 221 ?   ?   ?   A . n 
B 1 222 PRO 222 222 ?   ?   ?   A . n 
B 1 223 LEU 223 223 ?   ?   ?   A . n 
B 1 224 GLY 224 224 ?   ?   ?   A . n 
B 1 225 ALA 225 225 ?   ?   ?   A . n 
B 1 226 ALA 226 226 226 ALA ALA A . n 
B 1 227 GLN 227 227 227 GLN GLN A . n 
B 1 228 PRO 228 228 228 PRO PRO A . n 
B 1 229 ALA 229 229 229 ALA ALA A . n 
B 1 230 PRO 230 230 230 PRO PRO A . n 
B 1 231 ALA 231 231 231 ALA ALA A . n 
B 1 232 TRP 232 232 232 TRP TRP A . n 
B 1 233 THR 233 233 233 THR THR A . n 
B 1 234 THR 234 234 234 THR THR A . n 
B 1 235 PHE 235 235 235 PHE PHE A . n 
B 1 236 ARG 236 236 236 ARG ARG A . n 
B 1 237 VAL 237 237 237 VAL VAL A . n 
B 1 238 GLY 238 238 238 GLY GLY A . n 
B 1 239 LEU 239 239 239 LEU LEU A . n 
B 1 240 PHE 240 240 240 PHE PHE A . n 
B 1 241 CYS 241 241 241 CYS CYS A . n 
B 1 242 GLY 242 242 242 GLY GLY A . n 
B 1 243 ILE 243 243 243 ILE ILE A . n 
B 1 244 PHE 244 244 244 PHE PHE A . n 
B 1 245 ILE 245 245 245 ILE ILE A . n 
B 1 246 VAL 246 246 246 VAL VAL A . n 
B 1 247 LEU 247 247 247 LEU LEU A . n 
B 1 248 ASN 248 248 248 ASN ASN A . n 
B 1 249 ILE 249 249 249 ILE ILE A . n 
B 1 250 THR 250 250 250 THR THR A . n 
B 1 251 LEU 251 251 251 LEU LEU A . n 
B 1 252 VAL 252 252 252 VAL VAL A . n 
B 1 253 LEU 253 253 253 LEU LEU A . n 
B 1 254 ALA 254 254 254 ALA ALA A . n 
B 1 255 ALA 255 255 255 ALA ALA A . n 
B 1 256 VAL 256 256 256 VAL VAL A . n 
B 1 257 PHE 257 257 257 PHE PHE A . n 
B 1 258 LYS 258 258 258 LYS LYS A . n 
B 1 259 LEU 259 259 259 LEU LEU A . n 
B 1 260 GLU 260 260 260 GLU GLU A . n 
B 1 261 THR 261 261 261 THR THR A . n 
B 1 262 ASP 262 262 262 ASP ASP A . n 
B 1 263 ARG 263 263 263 ARG ARG A . n 
B 1 264 SER 264 264 264 SER SER A . n 
B 1 265 ILE 265 265 265 ILE ILE A . n 
B 1 266 TRP 266 266 266 TRP TRP A . n 
B 1 267 PRO 267 267 267 PRO PRO A . n 
B 1 268 LEU 268 268 268 LEU LEU A . n 
B 1 269 ILE 269 269 269 ILE ILE A . n 
B 1 270 ARG 270 270 270 ARG ARG A . n 
B 1 271 ILE 271 271 271 ILE ILE A . n 
B 1 272 TYR 272 272 272 TYR TYR A . n 
B 1 273 ARG 273 273 273 ARG ARG A . n 
B 1 274 GLY 274 274 274 GLY GLY A . n 
B 1 275 GLY 275 275 275 GLY GLY A . n 
B 1 276 PHE 276 276 276 PHE PHE A . n 
B 1 277 LEU 277 277 277 LEU LEU A . n 
B 1 278 LEU 278 278 278 LEU LEU A . n 
B 1 279 ILE 279 279 279 ILE ILE A . n 
B 1 280 GLU 280 280 280 GLU GLU A . n 
B 1 281 PHE 281 281 281 PHE PHE A . n 
B 1 282 LEU 282 282 282 LEU LEU A . n 
B 1 283 PHE 283 283 283 PHE PHE A . n 
B 1 284 LEU 284 284 284 LEU LEU A . n 
B 1 285 LEU 285 285 285 LEU LEU A . n 
B 1 286 GLY 286 286 286 GLY GLY A . n 
B 1 287 ILE 287 287 287 ILE ILE A . n 
B 1 288 ASN 288 288 288 ASN ASN A . n 
B 1 289 THR 289 289 289 THR THR A . n 
B 1 290 TYR 290 290 290 TYR TYR A . n 
B 1 291 GLY 291 291 291 GLY GLY A . n 
B 1 292 TRP 292 292 292 TRP TRP A . n 
B 1 293 ARG 293 293 293 ARG ARG A . n 
B 1 294 GLN 294 294 294 GLN GLN A . n 
B 1 295 ALA 295 295 295 ALA ALA A . n 
B 1 296 GLY 296 296 296 GLY GLY A . n 
B 1 297 VAL 297 297 297 VAL VAL A . n 
B 1 298 ASN 298 298 298 ASN ASN A . n 
B 1 299 HIS 299 299 299 HIS HIS A . n 
B 1 300 VAL 300 300 300 VAL VAL A . n 
B 1 301 LEU 301 301 301 LEU LEU A . n 
B 1 302 ILE 302 302 302 ILE ILE A . n 
B 1 303 PHE 303 303 303 PHE PHE A . n 
B 1 304 GLU 304 304 304 GLU GLU A . n 
B 1 305 LEU 305 305 305 LEU LEU A . n 
B 1 306 ASN 306 306 306 ASN ASN A . n 
B 1 307 PRO 307 307 307 PRO PRO A . n 
B 1 308 ARG 308 308 308 ARG ARG A . n 
B 1 309 SER 309 309 309 SER SER A . n 
B 1 310 ASN 310 310 310 ASN ASN A . n 
B 1 311 LEU 311 311 311 LEU LEU A . n 
B 1 312 SER 312 312 312 SER SER A . n 
B 1 313 HIS 313 313 313 HIS HIS A . n 
B 1 314 GLN 314 314 314 GLN GLN A . n 
B 1 315 HIS 315 315 315 HIS HIS A . n 
B 1 316 LEU 316 316 316 LEU LEU A . n 
B 1 317 PHE 317 317 317 PHE PHE A . n 
B 1 318 GLU 318 318 318 GLU GLU A . n 
B 1 319 ILE 319 319 319 ILE ILE A . n 
B 1 320 ALA 320 320 320 ALA ALA A . n 
B 1 321 GLY 321 321 321 GLY GLY A . n 
B 1 322 PHE 322 322 322 PHE PHE A . n 
B 1 323 LEU 323 323 323 LEU LEU A . n 
B 1 324 GLY 324 324 324 GLY GLY A . n 
B 1 325 ILE 325 325 325 ILE ILE A . n 
B 1 326 LEU 326 326 326 LEU LEU A . n 
B 1 327 TRP 327 327 327 TRP TRP A . n 
B 1 328 CYS 328 328 328 CYS CYS A . n 
B 1 329 LEU 329 329 329 LEU LEU A . n 
B 1 330 SER 330 330 330 SER SER A . n 
B 1 331 LEU 331 331 331 LEU LEU A . n 
B 1 332 LEU 332 332 332 LEU LEU A . n 
B 1 333 ALA 333 333 333 ALA ALA A . n 
B 1 334 CYS 334 334 334 CYS CYS A . n 
B 1 335 PHE 335 335 335 PHE PHE A . n 
B 1 336 PHE 336 336 336 PHE PHE A . n 
B 1 337 ALA 337 337 337 ALA ALA A . n 
B 1 338 PRO 338 338 338 PRO PRO A . n 
B 1 339 ILE 339 339 339 ILE ILE A . n 
B 1 340 SER 340 340 340 SER SER A . n 
B 1 341 VAL 341 341 341 VAL VAL A . n 
B 1 342 ILE 342 342 342 ILE ILE A . n 
B 1 343 PRO 343 343 343 PRO PRO A . n 
B 1 344 THR 344 344 344 THR THR A . n 
B 1 345 TYR 345 345 345 TYR TYR A . n 
B 1 346 VAL 346 346 346 VAL VAL A . n 
B 1 347 TYR 347 347 347 TYR TYR A . n 
B 1 348 PRO 348 348 348 PRO PRO A . n 
B 1 349 LEU 349 349 349 LEU LEU A . n 
B 1 350 ALA 350 350 350 ALA ALA A . n 
B 1 351 LEU 351 351 351 LEU LEU A . n 
B 1 352 TYR 352 352 352 TYR TYR A . n 
B 1 353 GLY 353 353 353 GLY GLY A . n 
B 1 354 PHE 354 354 354 PHE PHE A . n 
B 1 355 MET 355 355 355 MET MET A . n 
B 1 356 VAL 356 356 356 VAL VAL A . n 
B 1 357 PHE 357 357 357 PHE PHE A . n 
B 1 358 PHE 358 358 358 PHE PHE A . n 
B 1 359 LEU 359 359 359 LEU LEU A . n 
B 1 360 ILE 360 360 360 ILE ILE A . n 
B 1 361 ASN 361 361 361 ASN ASN A . n 
B 1 362 PRO 362 362 362 PRO PRO A . n 
B 1 363 THR 363 363 363 THR THR A . n 
B 1 364 LYS 364 364 364 LYS LYS A . n 
B 1 365 THR 365 365 365 THR THR A . n 
B 1 366 PHE 366 366 366 PHE PHE A . n 
B 1 367 TYR 367 367 367 TYR TYR A . n 
B 1 368 TYR 368 368 368 TYR TYR A . n 
B 1 369 LYS 369 369 369 LYS LYS A . n 
B 1 370 SER 370 370 370 SER SER A . n 
B 1 371 ARG 371 371 371 ARG ARG A . n 
B 1 372 PHE 372 372 372 PHE PHE A . n 
B 1 373 TRP 373 373 373 TRP TRP A . n 
B 1 374 LEU 374 374 374 LEU LEU A . n 
B 1 375 LEU 375 375 375 LEU LEU A . n 
B 1 376 LYS 376 376 376 LYS LYS A . n 
B 1 377 LEU 377 377 377 LEU LEU A . n 
B 1 378 LEU 378 378 378 LEU LEU A . n 
B 1 379 PHE 379 379 379 PHE PHE A . n 
B 1 380 ARG 380 380 380 ARG ARG A . n 
B 1 381 VAL 381 381 381 VAL VAL A . n 
B 1 382 PHE 382 382 382 PHE PHE A . n 
B 1 383 THR 383 383 383 THR THR A . n 
B 1 384 ALA 384 384 384 ALA ALA A . n 
B 1 385 PRO 385 385 385 PRO PRO A . n 
B 1 386 PHE 386 386 386 PHE PHE A . n 
B 1 387 HIS 387 387 387 HIS HIS A . n 
B 1 388 LYS 388 388 388 LYS LYS A . n 
B 1 389 VAL 389 389 389 VAL VAL A . n 
B 1 390 GLY 390 390 390 GLY GLY A . n 
B 1 391 PHE 391 391 391 PHE PHE A . n 
B 1 392 ALA 392 392 392 ALA ALA A . n 
B 1 393 ASP 393 393 393 ASP ASP A . n 
B 1 394 PHE 394 394 394 PHE PHE A . n 
B 1 395 TRP 395 395 395 TRP TRP A . n 
B 1 396 LEU 396 396 396 LEU LEU A . n 
B 1 397 ALA 397 397 397 ALA ALA A . n 
B 1 398 ASP 398 398 398 ASP ASP A . n 
B 1 399 GLN 399 399 399 GLN GLN A . n 
B 1 400 LEU 400 400 400 LEU LEU A . n 
B 1 401 ASN 401 401 401 ASN ASN A . n 
B 1 402 SER 402 402 402 SER SER A . n 
B 1 403 LEU 403 403 403 LEU LEU A . n 
B 1 404 SER 404 404 404 SER SER A . n 
B 1 405 VAL 405 405 405 VAL VAL A . n 
B 1 406 ILE 406 406 406 ILE ILE A . n 
B 1 407 LEU 407 407 407 LEU LEU A . n 
B 1 408 MET 408 408 408 MET MET A . n 
B 1 409 ASP 409 409 409 ASP ASP A . n 
B 1 410 LEU 410 410 410 LEU LEU A . n 
B 1 411 GLU 411 411 411 GLU GLU A . n 
B 1 412 TYR 412 412 412 TYR TYR A . n 
B 1 413 MET 413 413 413 MET MET A . n 
B 1 414 ILE 414 414 414 ILE ILE A . n 
B 1 415 CYS 415 415 415 CYS CYS A . n 
B 1 416 PHE 416 416 416 PHE PHE A . n 
B 1 417 TYR 417 417 417 TYR TYR A . n 
B 1 418 SER 418 418 418 SER SER A . n 
B 1 419 LEU 419 419 419 LEU LEU A . n 
B 1 420 GLU 420 420 420 GLU GLU A . n 
B 1 421 LEU 421 421 421 LEU LEU A . n 
B 1 422 LYS 422 422 422 LYS LYS A . n 
B 1 423 TRP 423 423 423 TRP TRP A . n 
B 1 424 ASP 424 424 424 ASP ASP A . n 
B 1 425 GLU 425 425 425 GLU GLU A . n 
B 1 426 SER 426 426 426 SER SER A . n 
B 1 427 LYS 427 427 427 LYS LYS A . n 
B 1 428 GLY 428 428 428 GLY GLY A . n 
B 1 429 LEU 429 429 429 LEU LEU A . n 
B 1 430 LEU 430 430 430 LEU LEU A . n 
B 1 431 PRO 431 431 431 PRO PRO A . n 
B 1 432 ASN 432 432 432 ASN ASN A . n 
B 1 433 ASN 433 433 433 ASN ASN A . n 
B 1 434 SER 434 434 434 SER SER A . n 
B 1 435 GLU 435 435 435 GLU GLU A . n 
B 1 436 GLU 436 436 436 GLU GLU A . n 
B 1 437 SER 437 437 437 SER SER A . n 
B 1 438 GLY 438 438 438 GLY GLY A . n 
B 1 439 ILE 439 439 439 ILE ILE A . n 
B 1 440 CYS 440 440 440 CYS CYS A . n 
B 1 441 HIS 441 441 441 HIS HIS A . n 
B 1 442 LYS 442 442 442 LYS LYS A . n 
B 1 443 TYR 443 443 443 TYR TYR A . n 
B 1 444 THR 444 444 444 THR THR A . n 
B 1 445 TYR 445 445 445 TYR TYR A . n 
B 1 446 GLY 446 446 446 GLY GLY A . n 
B 1 447 VAL 447 447 447 VAL VAL A . n 
B 1 448 ARG 448 448 448 ARG ARG A . n 
B 1 449 ALA 449 449 449 ALA ALA A . n 
B 1 450 ILE 450 450 450 ILE ILE A . n 
B 1 451 VAL 451 451 451 VAL VAL A . n 
B 1 452 GLN 452 452 452 GLN GLN A . n 
B 1 453 CYS 453 453 453 CYS CYS A . n 
B 1 454 ILE 454 454 454 ILE ILE A . n 
B 1 455 PRO 455 455 455 PRO PRO A . n 
B 1 456 ALA 456 456 456 ALA ALA A . n 
B 1 457 TRP 457 457 457 TRP TRP A . n 
B 1 458 LEU 458 458 458 LEU LEU A . n 
B 1 459 ARG 459 459 459 ARG ARG A . n 
B 1 460 PHE 460 460 460 PHE PHE A . n 
B 1 461 ILE 461 461 461 ILE ILE A . n 
B 1 462 GLN 462 462 462 GLN GLN A . n 
B 1 463 CYS 463 463 463 CYS CYS A . n 
B 1 464 LEU 464 464 464 LEU LEU A . n 
B 1 465 ARG 465 465 465 ARG ARG A . n 
B 1 466 ARG 466 466 466 ARG ARG A . n 
B 1 467 TYR 467 467 467 TYR TYR A . n 
B 1 468 ARG 468 468 468 ARG ARG A . n 
B 1 469 ASP 469 469 469 ASP ASP A . n 
B 1 470 THR 470 470 470 THR THR A . n 
B 1 471 LYS 471 471 471 LYS LYS A . n 
B 1 472 ARG 472 472 472 ARG ARG A . n 
B 1 473 ALA 473 473 473 ALA ALA A . n 
B 1 474 PHE 474 474 474 PHE PHE A . n 
B 1 475 PRO 475 475 475 PRO PRO A . n 
B 1 476 HIS 476 476 476 HIS HIS A . n 
B 1 477 LEU 477 477 477 LEU LEU A . n 
B 1 478 VAL 478 478 478 VAL VAL A . n 
B 1 479 ASN 479 479 479 ASN ASN A . n 
B 1 480 ALA 480 480 480 ALA ALA A . n 
B 1 481 GLY 481 481 481 GLY GLY A . n 
B 1 482 LYS 482 482 482 LYS LYS A . n 
B 1 483 TYR 483 483 483 TYR TYR A . n 
B 1 484 SER 484 484 484 SER SER A . n 
B 1 485 THR 485 485 485 THR THR A . n 
B 1 486 THR 486 486 486 THR THR A . n 
B 1 487 PHE 487 487 487 PHE PHE A . n 
B 1 488 PHE 488 488 488 PHE PHE A . n 
B 1 489 MET 489 489 489 MET MET A . n 
B 1 490 VAL 490 490 490 VAL VAL A . n 
B 1 491 THR 491 491 491 THR THR A . n 
B 1 492 PHE 492 492 492 PHE PHE A . n 
B 1 493 ALA 493 493 493 ALA ALA A . n 
B 1 494 ALA 494 494 494 ALA ALA A . n 
B 1 495 LEU 495 495 495 LEU LEU A . n 
B 1 496 TYR 496 496 496 TYR TYR A . n 
B 1 497 SER 497 497 497 SER SER A . n 
B 1 498 THR 498 498 498 THR THR A . n 
B 1 499 HIS 499 499 499 HIS HIS A . n 
B 1 500 LYS 500 500 500 LYS LYS A . n 
B 1 501 GLU 501 501 501 GLU GLU A . n 
B 1 502 ARG 502 502 502 ARG ARG A . n 
B 1 503 GLY 503 503 503 GLY GLY A . n 
B 1 504 HIS 504 504 504 HIS HIS A . n 
B 1 505 SER 505 505 505 SER SER A . n 
B 1 506 ASP 506 506 506 ASP ASP A . n 
B 1 507 THR 507 507 507 THR THR A . n 
B 1 508 MET 508 508 508 MET MET A . n 
B 1 509 VAL 509 509 509 VAL VAL A . n 
B 1 510 PHE 510 510 510 PHE PHE A . n 
B 1 511 PHE 511 511 511 PHE PHE A . n 
B 1 512 TYR 512 512 512 TYR TYR A . n 
B 1 513 LEU 513 513 513 LEU LEU A . n 
B 1 514 TRP 514 514 514 TRP TRP A . n 
B 1 515 ILE 515 515 515 ILE ILE A . n 
B 1 516 VAL 516 516 516 VAL VAL A . n 
B 1 517 PHE 517 517 517 PHE PHE A . n 
B 1 518 TYR 518 518 518 TYR TYR A . n 
B 1 519 ILE 519 519 519 ILE ILE A . n 
B 1 520 ILE 520 520 520 ILE ILE A . n 
B 1 521 SER 521 521 521 SER SER A . n 
B 1 522 SER 522 522 522 SER SER A . n 
B 1 523 CYS 523 523 523 CYS CYS A . n 
B 1 524 TYR 524 524 524 TYR TYR A . n 
B 1 525 THR 525 525 525 THR THR A . n 
B 1 526 LEU 526 526 526 LEU LEU A . n 
B 1 527 ILE 527 527 527 ILE ILE A . n 
B 1 528 TRP 528 528 528 TRP TRP A . n 
B 1 529 ASP 529 529 529 ASP ASP A . n 
B 1 530 LEU 530 530 530 LEU LEU A . n 
B 1 531 LYS 531 531 531 LYS LYS A . n 
B 1 532 MET 532 532 532 MET MET A . n 
B 1 533 ASP 533 533 533 ASP ASP A . n 
B 1 534 TRP 534 534 534 TRP TRP A . n 
B 1 535 GLY 535 535 535 GLY GLY A . n 
B 1 536 LEU 536 536 536 LEU LEU A . n 
B 1 537 PHE 537 537 537 PHE PHE A . n 
B 1 538 ASP 538 538 538 ASP ASP A . n 
B 1 539 LYS 539 539 539 LYS LYS A . n 
B 1 540 ASN 540 540 540 ASN ASN A . n 
B 1 541 ALA 541 541 541 ALA ALA A . n 
B 1 542 GLY 542 542 542 GLY GLY A . n 
B 1 543 GLU 543 543 543 GLU GLU A . n 
B 1 544 ASN 544 544 544 ASN ASN A . n 
B 1 545 THR 545 545 545 THR THR A . n 
B 1 546 PHE 546 546 546 PHE PHE A . n 
B 1 547 LEU 547 547 547 LEU LEU A . n 
B 1 548 ARG 548 548 548 ARG ARG A . n 
B 1 549 GLU 549 549 549 GLU GLU A . n 
B 1 550 GLU 550 550 550 GLU GLU A . n 
B 1 551 ILE 551 551 551 ILE ILE A . n 
B 1 552 VAL 552 552 552 VAL VAL A . n 
B 1 553 TYR 553 553 553 TYR TYR A . n 
B 1 554 PRO 554 554 554 PRO PRO A . n 
B 1 555 GLN 555 555 555 GLN GLN A . n 
B 1 556 LYS 556 556 556 LYS LYS A . n 
B 1 557 ALA 557 557 557 ALA ALA A . n 
B 1 558 TYR 558 558 558 TYR TYR A . n 
B 1 559 TYR 559 559 559 TYR TYR A . n 
B 1 560 TYR 560 560 560 TYR TYR A . n 
B 1 561 CYS 561 561 561 CYS CYS A . n 
B 1 562 ALA 562 562 562 ALA ALA A . n 
B 1 563 ILE 563 563 563 ILE ILE A . n 
B 1 564 ILE 564 564 564 ILE ILE A . n 
B 1 565 GLU 565 565 565 GLU GLU A . n 
B 1 566 ASP 566 566 566 ASP ASP A . n 
B 1 567 VAL 567 567 567 VAL VAL A . n 
B 1 568 ILE 568 568 568 ILE ILE A . n 
B 1 569 LEU 569 569 569 LEU LEU A . n 
B 1 570 ARG 570 570 570 ARG ARG A . n 
B 1 571 PHE 571 571 571 PHE PHE A . n 
B 1 572 ALA 572 572 572 ALA ALA A . n 
B 1 573 TRP 573 573 573 TRP TRP A . n 
B 1 574 THR 574 574 574 THR THR A . n 
B 1 575 ILE 575 575 575 ILE ILE A . n 
B 1 576 GLN 576 576 576 GLN GLN A . n 
B 1 577 ILE 577 577 577 ILE ILE A . n 
B 1 578 SER 578 578 578 SER SER A . n 
B 1 579 ILE 579 579 579 ILE ILE A . n 
B 1 580 THR 580 580 580 THR THR A . n 
B 1 581 SER 581 581 581 SER SER A . n 
B 1 582 THR 582 582 582 THR THR A . n 
B 1 583 THR 583 583 583 THR THR A . n 
B 1 584 LEU 584 584 584 LEU LEU A . n 
B 1 585 LEU 585 585 585 LEU LEU A . n 
B 1 586 PRO 586 586 586 PRO PRO A . n 
B 1 587 HIS 587 587 587 HIS HIS A . n 
B 1 588 SER 588 588 588 SER SER A . n 
B 1 589 GLY 589 589 589 GLY GLY A . n 
B 1 590 ASP 590 590 590 ASP ASP A . n 
B 1 591 ILE 591 591 591 ILE ILE A . n 
B 1 592 ILE 592 592 592 ILE ILE A . n 
B 1 593 ALA 593 593 593 ALA ALA A . n 
B 1 594 THR 594 594 594 THR THR A . n 
B 1 595 VAL 595 595 595 VAL VAL A . n 
B 1 596 PHE 596 596 596 PHE PHE A . n 
B 1 597 ALA 597 597 597 ALA ALA A . n 
B 1 598 PRO 598 598 598 PRO PRO A . n 
B 1 599 LEU 599 599 599 LEU LEU A . n 
B 1 600 GLU 600 600 600 GLU GLU A . n 
B 1 601 VAL 601 601 601 VAL VAL A . n 
B 1 602 PHE 602 602 602 PHE PHE A . n 
B 1 603 ARG 603 603 603 ARG ARG A . n 
B 1 604 ARG 604 604 604 ARG ARG A . n 
B 1 605 PHE 605 605 605 PHE PHE A . n 
B 1 606 VAL 606 606 606 VAL VAL A . n 
B 1 607 TRP 607 607 607 TRP TRP A . n 
B 1 608 ASN 608 608 608 ASN ASN A . n 
B 1 609 PHE 609 609 609 PHE PHE A . n 
B 1 610 PHE 610 610 610 PHE PHE A . n 
B 1 611 ARG 611 611 611 ARG ARG A . n 
B 1 612 LEU 612 612 612 LEU LEU A . n 
B 1 613 GLU 613 613 613 GLU GLU A . n 
B 1 614 ASN 614 614 614 ASN ASN A . n 
B 1 615 GLU 615 615 615 GLU GLU A . n 
B 1 616 HIS 616 616 616 HIS HIS A . n 
B 1 617 LEU 617 617 617 LEU LEU A . n 
B 1 618 ASN 618 618 618 ASN ASN A . n 
B 1 619 ASN 619 619 619 ASN ASN A . n 
B 1 620 CYS 620 620 620 CYS CYS A . n 
B 1 621 GLY 621 621 621 GLY GLY A . n 
B 1 622 GLU 622 622 622 GLU GLU A . n 
B 1 623 PHE 623 623 623 PHE PHE A . n 
B 1 624 ARG 624 624 624 ARG ARG A . n 
B 1 625 ALA 625 625 625 ALA ALA A . n 
B 1 626 VAL 626 626 626 VAL VAL A . n 
B 1 627 ARG 627 627 ?   ?   ?   A . n 
B 1 628 ASP 628 628 ?   ?   ?   A . n 
B 1 629 ILE 629 629 ?   ?   ?   A . n 
B 1 630 SER 630 630 ?   ?   ?   A . n 
B 1 631 VAL 631 631 ?   ?   ?   A . n 
B 1 632 ALA 632 632 ?   ?   ?   A . n 
B 1 633 PRO 633 633 ?   ?   ?   A . n 
B 1 634 LEU 634 634 ?   ?   ?   A . n 
B 1 635 ASN 635 635 ?   ?   ?   A . n 
B 1 636 ALA 636 636 ?   ?   ?   A . n 
B 1 637 ASP 637 637 ?   ?   ?   A . n 
B 1 638 ASP 638 638 ?   ?   ?   A . n 
B 1 639 GLN 639 639 ?   ?   ?   A . n 
B 1 640 THR 640 640 ?   ?   ?   A . n 
B 1 641 LEU 641 641 ?   ?   ?   A . n 
B 1 642 LEU 642 642 ?   ?   ?   A . n 
B 1 643 GLU 643 643 ?   ?   ?   A . n 
B 1 644 GLN 644 644 ?   ?   ?   A . n 
B 1 645 MET 645 645 ?   ?   ?   A . n 
B 1 646 MET 646 646 ?   ?   ?   A . n 
B 1 647 ASP 647 647 ?   ?   ?   A . n 
B 1 648 GLN 648 648 ?   ?   ?   A . n 
B 1 649 ASP 649 649 ?   ?   ?   A . n 
B 1 650 ASP 650 650 ?   ?   ?   A . n 
B 1 651 GLY 651 651 ?   ?   ?   A . n 
B 1 652 VAL 652 652 ?   ?   ?   A . n 
B 1 653 ARG 653 653 ?   ?   ?   A . n 
B 1 654 ASN 654 654 ?   ?   ?   A . n 
B 1 655 ARG 655 655 ?   ?   ?   A . n 
B 1 656 GLN 656 656 ?   ?   ?   A . n 
B 1 657 LYS 657 657 ?   ?   ?   A . n 
B 1 658 ASN 658 658 ?   ?   ?   A . n 
B 1 659 ARG 659 659 ?   ?   ?   A . n 
B 1 660 SER 660 660 ?   ?   ?   A . n 
B 1 661 TRP 661 661 ?   ?   ?   A . n 
B 1 662 LYS 662 662 ?   ?   ?   A . n 
B 1 663 TYR 663 663 ?   ?   ?   A . n 
B 1 664 ASN 664 664 ?   ?   ?   A . n 
B 1 665 GLN 665 665 ?   ?   ?   A . n 
B 1 666 SER 666 666 ?   ?   ?   A . n 
B 1 667 ILE 667 667 ?   ?   ?   A . n 
B 1 668 SER 668 668 ?   ?   ?   A . n 
B 1 669 LEU 669 669 ?   ?   ?   A . n 
B 1 670 ARG 670 670 ?   ?   ?   A . n 
B 1 671 ARG 671 671 ?   ?   ?   A . n 
B 1 672 PRO 672 672 ?   ?   ?   A . n 
B 1 673 ARG 673 673 ?   ?   ?   A . n 
B 1 674 LEU 674 674 ?   ?   ?   A . n 
B 1 675 ALA 675 675 ?   ?   ?   A . n 
B 1 676 SER 676 676 ?   ?   ?   A . n 
B 1 677 GLN 677 677 ?   ?   ?   A . n 
B 1 678 SER 678 678 ?   ?   ?   A . n 
B 1 679 LYS 679 679 ?   ?   ?   A . n 
B 1 680 ALA 680 680 ?   ?   ?   A . n 
B 1 681 ARG 681 681 ?   ?   ?   A . n 
B 1 682 ASP 682 682 ?   ?   ?   A . n 
B 1 683 THR 683 683 ?   ?   ?   A . n 
B 1 684 LYS 684 684 ?   ?   ?   A . n 
B 1 685 VAL 685 685 ?   ?   ?   A . n 
B 1 686 LEU 686 686 ?   ?   ?   A . n 
B 1 687 ILE 687 687 ?   ?   ?   A . n 
B 1 688 GLU 688 688 ?   ?   ?   A . n 
B 1 689 ASP 689 689 ?   ?   ?   A . n 
B 1 690 THR 690 690 ?   ?   ?   A . n 
B 1 691 ASP 691 691 ?   ?   ?   A . n 
B 1 692 ASP 692 692 ?   ?   ?   A . n 
B 1 693 GLU 693 693 ?   ?   ?   A . n 
B 1 694 ALA 694 694 ?   ?   ?   A . n 
B 1 695 ASN 695 695 ?   ?   ?   A . n 
B 1 696 THR 696 696 ?   ?   ?   A . n 
B 1 697 SER 697 697 ?   ?   ?   A . n 
B 1 698 ARG 698 698 ?   ?   ?   A . n 
B 1 699 GLU 699 699 ?   ?   ?   A . n 
B 1 700 ASN 700 700 ?   ?   ?   A . n 
B 1 701 LEU 701 701 ?   ?   ?   A . n 
B 1 702 TYR 702 702 ?   ?   ?   A . n 
B 1 703 PHE 703 703 ?   ?   ?   A . n 
B 1 704 GLN 704 704 ?   ?   ?   A . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 ACD ? ? ACD ? ? 'SUBJECT OF INVESTIGATION' ? 
2 LPE ? ? LPE ? ? 'SUBJECT OF INVESTIGATION' ? 
3 PLM ? ? PLM ? ? 'SUBJECT OF INVESTIGATION' ? 
4 CLR ? ? CLR ? ? 'SUBJECT OF INVESTIGATION' ? 
5 3PE ? ? 3PE ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C  2 CLR 1 801 701  CLR CLR B . 
D  3 3PE 1 802 801  3PE 3PE B . 
E  3 3PE 1 803 901  3PE 3PE B . 
F  2 CLR 1 804 1001 CLR CLR B . 
G  2 CLR 1 805 1301 CLR CLR B . 
H  2 CLR 1 806 1401 CLR CLR B . 
I  3 3PE 1 807 1701 3PE 3PE B . 
J  2 CLR 1 808 1801 CLR CLR B . 
K  2 CLR 1 809 1901 CLR CLR B . 
L  4 LPE 1 810 2001 LPE LPE B . 
M  5 PLM 1 811 2101 PLM PLM B . 
N  2 CLR 1 812 2201 CLR CLR B . 
O  6 ACD 1 813 2301 ACD ACD B . 
P  3 3PE 1 814 901  3PE 3PE B . 
Q  2 CLR 1 801 701  CLR CLR A . 
R  3 3PE 1 802 801  3PE 3PE A . 
S  2 CLR 1 803 1001 CLR CLR A . 
T  2 CLR 1 804 1301 CLR CLR A . 
U  2 CLR 1 805 1401 CLR CLR A . 
V  3 3PE 1 806 1701 3PE 3PE A . 
W  2 CLR 1 807 1801 CLR CLR A . 
X  2 CLR 1 808 1901 CLR CLR A . 
Y  4 LPE 1 809 2001 LPE LPE A . 
Z  5 PLM 1 810 2101 PLM PLM A . 
AA 2 CLR 1 811 2201 CLR CLR A . 
BA 6 ACD 1 812 2301 ACD ACD A . 
CA 7 HOH 1 901 6    HOH HOH B . 
CA 7 HOH 2 902 3    HOH HOH B . 
CA 7 HOH 3 903 4    HOH HOH B . 
CA 7 HOH 4 904 5    HOH HOH B . 
DA 7 HOH 1 901 8    HOH HOH A . 
DA 7 HOH 2 902 1    HOH HOH A . 
DA 7 HOH 3 903 2    HOH HOH A . 
DA 7 HOH 4 904 7    HOH HOH A . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9INE 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9INE 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9INE 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9INE 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.005  ? 7833  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.700  ? 10627 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 13.620 ? 1372  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039  ? 1168  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1174  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9INE 
_struct.title                        'Cryo-EM structure of human XPR1 in closed state in the presence of KIDINS220-1-432' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9INE 
_struct_keywords.text            'SLC53A1, transporter, phosphate, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A  N N 1 ? 
B  N N 1 ? 
C  N N 2 ? 
D  N N 3 ? 
E  N N 3 ? 
F  N N 2 ? 
G  N N 2 ? 
H  N N 2 ? 
I  N N 3 ? 
J  N N 2 ? 
K  N N 2 ? 
L  N N 4 ? 
M  N N 5 ? 
N  N N 2 ? 
O  N N 6 ? 
P  N N 3 ? 
Q  N N 2 ? 
R  N N 3 ? 
S  N N 2 ? 
T  N N 2 ? 
U  N N 2 ? 
V  N N 3 ? 
W  N N 2 ? 
X  N N 2 ? 
Y  N N 4 ? 
Z  N N 5 ? 
AA N N 2 ? 
BA N N 6 ? 
CA N N 7 ? 
DA N N 7 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    S53A1_HUMAN 
_struct_ref.pdbx_db_accession          Q9UBH6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEA
QRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKIL
KKHDKILETSRGADWRVAHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRSNLSHQHLFEIA
GFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQL
NSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYY
CAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQT
LLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9INE B 1 ? 696 ? Q9UBH6 1 ? 696 ? 1 696 
2 1 9INE A 1 ? 696 ? Q9UBH6 1 ? 696 ? 1 696 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9INE SER B 697 ? UNP Q9UBH6 ? ? 'expression tag' 697 1  
1 9INE ARG B 698 ? UNP Q9UBH6 ? ? 'expression tag' 698 2  
1 9INE GLU B 699 ? UNP Q9UBH6 ? ? 'expression tag' 699 3  
1 9INE ASN B 700 ? UNP Q9UBH6 ? ? 'expression tag' 700 4  
1 9INE LEU B 701 ? UNP Q9UBH6 ? ? 'expression tag' 701 5  
1 9INE TYR B 702 ? UNP Q9UBH6 ? ? 'expression tag' 702 6  
1 9INE PHE B 703 ? UNP Q9UBH6 ? ? 'expression tag' 703 7  
1 9INE GLN B 704 ? UNP Q9UBH6 ? ? 'expression tag' 704 8  
2 9INE SER A 697 ? UNP Q9UBH6 ? ? 'expression tag' 697 9  
2 9INE ARG A 698 ? UNP Q9UBH6 ? ? 'expression tag' 698 10 
2 9INE GLU A 699 ? UNP Q9UBH6 ? ? 'expression tag' 699 11 
2 9INE ASN A 700 ? UNP Q9UBH6 ? ? 'expression tag' 700 12 
2 9INE LEU A 701 ? UNP Q9UBH6 ? ? 'expression tag' 701 13 
2 9INE TYR A 702 ? UNP Q9UBH6 ? ? 'expression tag' 702 14 
2 9INE PHE A 703 ? UNP Q9UBH6 ? ? 'expression tag' 703 15 
2 9INE GLN A 704 ? UNP Q9UBH6 ? ? 'expression tag' 704 16 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA,DA 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 230 ? LYS A 258 ? PRO B 230 LYS B 258 1 ? 29 
HELX_P HELX_P2  AA2 ILE A 265 ? GLY A 296 ? ILE B 265 GLY B 296 1 ? 32 
HELX_P HELX_P3  AA3 ASN A 298 ? GLU A 304 ? ASN B 298 GLU B 304 1 ? 7  
HELX_P HELX_P4  AA4 SER A 312 ? PHE A 336 ? SER B 312 PHE B 336 1 ? 25 
HELX_P HELX_P5  AA5 TYR A 345 ? ILE A 360 ? TYR B 345 ILE B 360 1 ? 16 
HELX_P HELX_P6  AA6 TYR A 367 ? PHE A 382 ? TYR B 367 PHE B 382 1 ? 16 
HELX_P HELX_P7  AA7 THR A 383 ? HIS A 387 ? THR B 383 HIS B 387 5 ? 5  
HELX_P HELX_P8  AA8 GLY A 390 ? LEU A 403 ? GLY B 390 LEU B 403 1 ? 14 
HELX_P HELX_P9  AA9 LEU A 403 ? LEU A 419 ? LEU B 403 LEU B 419 1 ? 17 
HELX_P HELX_P10 AB1 GLY A 446 ? LYS A 471 ? GLY B 446 LYS B 471 1 ? 26 
HELX_P HELX_P11 AB2 ARG A 472 ? ARG A 502 ? ARG B 472 ARG B 502 1 ? 31 
HELX_P HELX_P12 AB3 ASP A 506 ? MET A 532 ? ASP B 506 MET B 532 1 ? 27 
HELX_P HELX_P13 AB4 ASP A 538 ? GLY A 542 ? ASP B 538 GLY B 542 5 ? 5  
HELX_P HELX_P14 AB5 LYS A 556 ? SER A 578 ? LYS B 556 SER B 578 1 ? 23 
HELX_P HELX_P15 AB6 SER A 588 ? ASN A 618 ? SER B 588 ASN B 618 1 ? 31 
HELX_P HELX_P16 AB7 PRO B 230 ? LYS B 258 ? PRO A 230 LYS A 258 1 ? 29 
HELX_P HELX_P17 AB8 ILE B 265 ? GLY B 296 ? ILE A 265 GLY A 296 1 ? 32 
HELX_P HELX_P18 AB9 ASN B 298 ? GLU B 304 ? ASN A 298 GLU A 304 1 ? 7  
HELX_P HELX_P19 AC1 SER B 312 ? PHE B 336 ? SER A 312 PHE A 336 1 ? 25 
HELX_P HELX_P20 AC2 TYR B 345 ? ILE B 360 ? TYR A 345 ILE A 360 1 ? 16 
HELX_P HELX_P21 AC3 TYR B 367 ? THR B 383 ? TYR A 367 THR A 383 1 ? 17 
HELX_P HELX_P22 AC4 ALA B 384 ? HIS B 387 ? ALA A 384 HIS A 387 5 ? 4  
HELX_P HELX_P23 AC5 GLY B 390 ? LEU B 403 ? GLY A 390 LEU A 403 1 ? 14 
HELX_P HELX_P24 AC6 LEU B 403 ? LEU B 419 ? LEU A 403 LEU A 419 1 ? 17 
HELX_P HELX_P25 AC7 GLY B 446 ? LYS B 471 ? GLY A 446 LYS A 471 1 ? 26 
HELX_P HELX_P26 AC8 ARG B 472 ? ARG B 502 ? ARG A 472 ARG A 502 1 ? 31 
HELX_P HELX_P27 AC9 ASP B 506 ? MET B 532 ? ASP A 506 MET A 532 1 ? 27 
HELX_P HELX_P28 AD1 ASP B 538 ? GLY B 542 ? ASP A 538 GLY A 542 5 ? 5  
HELX_P HELX_P29 AD2 LYS B 556 ? SER B 578 ? LYS A 556 SER A 578 1 ? 23 
HELX_P HELX_P30 AD3 SER B 588 ? ASN B 618 ? SER A 588 ASN A 618 1 ? 31 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 415 SG ? ? ? 1_555 A CYS 440 SG ? ? B CYS 415 B CYS 440 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf2 disulf ? ? B CYS 415 SG ? ? ? 1_555 B CYS 440 SG ? ? A CYS 415 A CYS 440 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 415 ? CYS A 440 ? CYS B 415 ? 1_555 CYS B 440 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 415 ? CYS B 440 ? CYS A 415 ? 1_555 CYS A 440 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 474 A . ? PHE 474 B PRO 475 A ? PRO 475 B 1 -1.07 
2 PHE 474 B . ? PHE 474 A PRO 475 B ? PRO 475 A 1 -1.16 
# 
_pdbx_entry_details.entry_id                   9INE 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE B 257 ? ? -96.24  -60.15 
2  1 THR B 261 ? ? -95.26  53.71  
3  1 PRO B 475 ? ? -99.05  38.11  
4  1 ILE B 519 ? ? 70.55   -54.26 
5  1 THR B 580 ? ? 72.43   -6.40  
6  1 LEU B 584 ? ? -102.46 72.98  
7  1 PHE A 257 ? ? -92.10  -62.73 
8  1 PRO A 475 ? ? -99.30  38.72  
9  1 ILE A 519 ? ? 70.09   -54.46 
10 1 THR A 580 ? ? 71.28   -6.09  
11 1 LEU A 584 ? ? -101.78 73.55  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9INE 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9INE 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.32 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               187463 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 XPR1-KIDINS220-1-432 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9INE 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9INE 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9INE 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 B MET 1   ? A MET 1   
2   1 Y 1 B LYS 2   ? A LYS 2   
3   1 Y 1 B PHE 3   ? A PHE 3   
4   1 Y 1 B ALA 4   ? A ALA 4   
5   1 Y 1 B GLU 5   ? A GLU 5   
6   1 Y 1 B HIS 6   ? A HIS 6   
7   1 Y 1 B LEU 7   ? A LEU 7   
8   1 Y 1 B SER 8   ? A SER 8   
9   1 Y 1 B ALA 9   ? A ALA 9   
10  1 Y 1 B HIS 10  ? A HIS 10  
11  1 Y 1 B ILE 11  ? A ILE 11  
12  1 Y 1 B THR 12  ? A THR 12  
13  1 Y 1 B PRO 13  ? A PRO 13  
14  1 Y 1 B GLU 14  ? A GLU 14  
15  1 Y 1 B TRP 15  ? A TRP 15  
16  1 Y 1 B ARG 16  ? A ARG 16  
17  1 Y 1 B LYS 17  ? A LYS 17  
18  1 Y 1 B GLN 18  ? A GLN 18  
19  1 Y 1 B TYR 19  ? A TYR 19  
20  1 Y 1 B ILE 20  ? A ILE 20  
21  1 Y 1 B GLN 21  ? A GLN 21  
22  1 Y 1 B TYR 22  ? A TYR 22  
23  1 Y 1 B GLU 23  ? A GLU 23  
24  1 Y 1 B ALA 24  ? A ALA 24  
25  1 Y 1 B PHE 25  ? A PHE 25  
26  1 Y 1 B LYS 26  ? A LYS 26  
27  1 Y 1 B ASP 27  ? A ASP 27  
28  1 Y 1 B MET 28  ? A MET 28  
29  1 Y 1 B LEU 29  ? A LEU 29  
30  1 Y 1 B TYR 30  ? A TYR 30  
31  1 Y 1 B SER 31  ? A SER 31  
32  1 Y 1 B ALA 32  ? A ALA 32  
33  1 Y 1 B GLN 33  ? A GLN 33  
34  1 Y 1 B ASP 34  ? A ASP 34  
35  1 Y 1 B GLN 35  ? A GLN 35  
36  1 Y 1 B ALA 36  ? A ALA 36  
37  1 Y 1 B PRO 37  ? A PRO 37  
38  1 Y 1 B SER 38  ? A SER 38  
39  1 Y 1 B VAL 39  ? A VAL 39  
40  1 Y 1 B GLU 40  ? A GLU 40  
41  1 Y 1 B VAL 41  ? A VAL 41  
42  1 Y 1 B THR 42  ? A THR 42  
43  1 Y 1 B ASP 43  ? A ASP 43  
44  1 Y 1 B GLU 44  ? A GLU 44  
45  1 Y 1 B ASP 45  ? A ASP 45  
46  1 Y 1 B THR 46  ? A THR 46  
47  1 Y 1 B VAL 47  ? A VAL 47  
48  1 Y 1 B LYS 48  ? A LYS 48  
49  1 Y 1 B ARG 49  ? A ARG 49  
50  1 Y 1 B TYR 50  ? A TYR 50  
51  1 Y 1 B PHE 51  ? A PHE 51  
52  1 Y 1 B ALA 52  ? A ALA 52  
53  1 Y 1 B LYS 53  ? A LYS 53  
54  1 Y 1 B PHE 54  ? A PHE 54  
55  1 Y 1 B GLU 55  ? A GLU 55  
56  1 Y 1 B GLU 56  ? A GLU 56  
57  1 Y 1 B LYS 57  ? A LYS 57  
58  1 Y 1 B PHE 58  ? A PHE 58  
59  1 Y 1 B PHE 59  ? A PHE 59  
60  1 Y 1 B GLN 60  ? A GLN 60  
61  1 Y 1 B THR 61  ? A THR 61  
62  1 Y 1 B CYS 62  ? A CYS 62  
63  1 Y 1 B GLU 63  ? A GLU 63  
64  1 Y 1 B LYS 64  ? A LYS 64  
65  1 Y 1 B GLU 65  ? A GLU 65  
66  1 Y 1 B LEU 66  ? A LEU 66  
67  1 Y 1 B ALA 67  ? A ALA 67  
68  1 Y 1 B LYS 68  ? A LYS 68  
69  1 Y 1 B ILE 69  ? A ILE 69  
70  1 Y 1 B ASN 70  ? A ASN 70  
71  1 Y 1 B THR 71  ? A THR 71  
72  1 Y 1 B PHE 72  ? A PHE 72  
73  1 Y 1 B TYR 73  ? A TYR 73  
74  1 Y 1 B SER 74  ? A SER 74  
75  1 Y 1 B GLU 75  ? A GLU 75  
76  1 Y 1 B LYS 76  ? A LYS 76  
77  1 Y 1 B LEU 77  ? A LEU 77  
78  1 Y 1 B ALA 78  ? A ALA 78  
79  1 Y 1 B GLU 79  ? A GLU 79  
80  1 Y 1 B ALA 80  ? A ALA 80  
81  1 Y 1 B GLN 81  ? A GLN 81  
82  1 Y 1 B ARG 82  ? A ARG 82  
83  1 Y 1 B ARG 83  ? A ARG 83  
84  1 Y 1 B PHE 84  ? A PHE 84  
85  1 Y 1 B ALA 85  ? A ALA 85  
86  1 Y 1 B THR 86  ? A THR 86  
87  1 Y 1 B LEU 87  ? A LEU 87  
88  1 Y 1 B GLN 88  ? A GLN 88  
89  1 Y 1 B ASN 89  ? A ASN 89  
90  1 Y 1 B GLU 90  ? A GLU 90  
91  1 Y 1 B LEU 91  ? A LEU 91  
92  1 Y 1 B GLN 92  ? A GLN 92  
93  1 Y 1 B SER 93  ? A SER 93  
94  1 Y 1 B SER 94  ? A SER 94  
95  1 Y 1 B LEU 95  ? A LEU 95  
96  1 Y 1 B ASP 96  ? A ASP 96  
97  1 Y 1 B ALA 97  ? A ALA 97  
98  1 Y 1 B GLN 98  ? A GLN 98  
99  1 Y 1 B LYS 99  ? A LYS 99  
100 1 Y 1 B GLU 100 ? A GLU 100 
101 1 Y 1 B SER 101 ? A SER 101 
102 1 Y 1 B THR 102 ? A THR 102 
103 1 Y 1 B GLY 103 ? A GLY 103 
104 1 Y 1 B VAL 104 ? A VAL 104 
105 1 Y 1 B THR 105 ? A THR 105 
106 1 Y 1 B THR 106 ? A THR 106 
107 1 Y 1 B LEU 107 ? A LEU 107 
108 1 Y 1 B ARG 108 ? A ARG 108 
109 1 Y 1 B GLN 109 ? A GLN 109 
110 1 Y 1 B ARG 110 ? A ARG 110 
111 1 Y 1 B ARG 111 ? A ARG 111 
112 1 Y 1 B LYS 112 ? A LYS 112 
113 1 Y 1 B PRO 113 ? A PRO 113 
114 1 Y 1 B VAL 114 ? A VAL 114 
115 1 Y 1 B PHE 115 ? A PHE 115 
116 1 Y 1 B HIS 116 ? A HIS 116 
117 1 Y 1 B LEU 117 ? A LEU 117 
118 1 Y 1 B SER 118 ? A SER 118 
119 1 Y 1 B HIS 119 ? A HIS 119 
120 1 Y 1 B GLU 120 ? A GLU 120 
121 1 Y 1 B GLU 121 ? A GLU 121 
122 1 Y 1 B ARG 122 ? A ARG 122 
123 1 Y 1 B VAL 123 ? A VAL 123 
124 1 Y 1 B GLN 124 ? A GLN 124 
125 1 Y 1 B HIS 125 ? A HIS 125 
126 1 Y 1 B ARG 126 ? A ARG 126 
127 1 Y 1 B ASN 127 ? A ASN 127 
128 1 Y 1 B ILE 128 ? A ILE 128 
129 1 Y 1 B LYS 129 ? A LYS 129 
130 1 Y 1 B ASP 130 ? A ASP 130 
131 1 Y 1 B LEU 131 ? A LEU 131 
132 1 Y 1 B LYS 132 ? A LYS 132 
133 1 Y 1 B LEU 133 ? A LEU 133 
134 1 Y 1 B ALA 134 ? A ALA 134 
135 1 Y 1 B PHE 135 ? A PHE 135 
136 1 Y 1 B SER 136 ? A SER 136 
137 1 Y 1 B GLU 137 ? A GLU 137 
138 1 Y 1 B PHE 138 ? A PHE 138 
139 1 Y 1 B TYR 139 ? A TYR 139 
140 1 Y 1 B LEU 140 ? A LEU 140 
141 1 Y 1 B SER 141 ? A SER 141 
142 1 Y 1 B LEU 142 ? A LEU 142 
143 1 Y 1 B ILE 143 ? A ILE 143 
144 1 Y 1 B LEU 144 ? A LEU 144 
145 1 Y 1 B LEU 145 ? A LEU 145 
146 1 Y 1 B GLN 146 ? A GLN 146 
147 1 Y 1 B ASN 147 ? A ASN 147 
148 1 Y 1 B TYR 148 ? A TYR 148 
149 1 Y 1 B GLN 149 ? A GLN 149 
150 1 Y 1 B ASN 150 ? A ASN 150 
151 1 Y 1 B LEU 151 ? A LEU 151 
152 1 Y 1 B ASN 152 ? A ASN 152 
153 1 Y 1 B PHE 153 ? A PHE 153 
154 1 Y 1 B THR 154 ? A THR 154 
155 1 Y 1 B GLY 155 ? A GLY 155 
156 1 Y 1 B PHE 156 ? A PHE 156 
157 1 Y 1 B ARG 157 ? A ARG 157 
158 1 Y 1 B LYS 158 ? A LYS 158 
159 1 Y 1 B ILE 159 ? A ILE 159 
160 1 Y 1 B LEU 160 ? A LEU 160 
161 1 Y 1 B LYS 161 ? A LYS 161 
162 1 Y 1 B LYS 162 ? A LYS 162 
163 1 Y 1 B HIS 163 ? A HIS 163 
164 1 Y 1 B ASP 164 ? A ASP 164 
165 1 Y 1 B LYS 165 ? A LYS 165 
166 1 Y 1 B ILE 166 ? A ILE 166 
167 1 Y 1 B LEU 167 ? A LEU 167 
168 1 Y 1 B GLU 168 ? A GLU 168 
169 1 Y 1 B THR 169 ? A THR 169 
170 1 Y 1 B SER 170 ? A SER 170 
171 1 Y 1 B ARG 171 ? A ARG 171 
172 1 Y 1 B GLY 172 ? A GLY 172 
173 1 Y 1 B ALA 173 ? A ALA 173 
174 1 Y 1 B ASP 174 ? A ASP 174 
175 1 Y 1 B TRP 175 ? A TRP 175 
176 1 Y 1 B ARG 176 ? A ARG 176 
177 1 Y 1 B VAL 177 ? A VAL 177 
178 1 Y 1 B ALA 178 ? A ALA 178 
179 1 Y 1 B HIS 179 ? A HIS 179 
180 1 Y 1 B VAL 180 ? A VAL 180 
181 1 Y 1 B GLU 181 ? A GLU 181 
182 1 Y 1 B VAL 182 ? A VAL 182 
183 1 Y 1 B ALA 183 ? A ALA 183 
184 1 Y 1 B PRO 184 ? A PRO 184 
185 1 Y 1 B PHE 185 ? A PHE 185 
186 1 Y 1 B TYR 186 ? A TYR 186 
187 1 Y 1 B THR 187 ? A THR 187 
188 1 Y 1 B CYS 188 ? A CYS 188 
189 1 Y 1 B LYS 189 ? A LYS 189 
190 1 Y 1 B LYS 190 ? A LYS 190 
191 1 Y 1 B ILE 191 ? A ILE 191 
192 1 Y 1 B ASN 192 ? A ASN 192 
193 1 Y 1 B GLN 193 ? A GLN 193 
194 1 Y 1 B LEU 194 ? A LEU 194 
195 1 Y 1 B ILE 195 ? A ILE 195 
196 1 Y 1 B SER 196 ? A SER 196 
197 1 Y 1 B GLU 197 ? A GLU 197 
198 1 Y 1 B THR 198 ? A THR 198 
199 1 Y 1 B GLU 199 ? A GLU 199 
200 1 Y 1 B ALA 200 ? A ALA 200 
201 1 Y 1 B VAL 201 ? A VAL 201 
202 1 Y 1 B VAL 202 ? A VAL 202 
203 1 Y 1 B THR 203 ? A THR 203 
204 1 Y 1 B ASN 204 ? A ASN 204 
205 1 Y 1 B GLU 205 ? A GLU 205 
206 1 Y 1 B LEU 206 ? A LEU 206 
207 1 Y 1 B GLU 207 ? A GLU 207 
208 1 Y 1 B ASP 208 ? A ASP 208 
209 1 Y 1 B GLY 209 ? A GLY 209 
210 1 Y 1 B ASP 210 ? A ASP 210 
211 1 Y 1 B ARG 211 ? A ARG 211 
212 1 Y 1 B GLN 212 ? A GLN 212 
213 1 Y 1 B LYS 213 ? A LYS 213 
214 1 Y 1 B ALA 214 ? A ALA 214 
215 1 Y 1 B MET 215 ? A MET 215 
216 1 Y 1 B LYS 216 ? A LYS 216 
217 1 Y 1 B ARG 217 ? A ARG 217 
218 1 Y 1 B LEU 218 ? A LEU 218 
219 1 Y 1 B ARG 219 ? A ARG 219 
220 1 Y 1 B VAL 220 ? A VAL 220 
221 1 Y 1 B PRO 221 ? A PRO 221 
222 1 Y 1 B PRO 222 ? A PRO 222 
223 1 Y 1 B LEU 223 ? A LEU 223 
224 1 Y 1 B GLY 224 ? A GLY 224 
225 1 Y 1 B ALA 225 ? A ALA 225 
226 1 Y 1 B ARG 627 ? A ARG 627 
227 1 Y 1 B ASP 628 ? A ASP 628 
228 1 Y 1 B ILE 629 ? A ILE 629 
229 1 Y 1 B SER 630 ? A SER 630 
230 1 Y 1 B VAL 631 ? A VAL 631 
231 1 Y 1 B ALA 632 ? A ALA 632 
232 1 Y 1 B PRO 633 ? A PRO 633 
233 1 Y 1 B LEU 634 ? A LEU 634 
234 1 Y 1 B ASN 635 ? A ASN 635 
235 1 Y 1 B ALA 636 ? A ALA 636 
236 1 Y 1 B ASP 637 ? A ASP 637 
237 1 Y 1 B ASP 638 ? A ASP 638 
238 1 Y 1 B GLN 639 ? A GLN 639 
239 1 Y 1 B THR 640 ? A THR 640 
240 1 Y 1 B LEU 641 ? A LEU 641 
241 1 Y 1 B LEU 642 ? A LEU 642 
242 1 Y 1 B GLU 643 ? A GLU 643 
243 1 Y 1 B GLN 644 ? A GLN 644 
244 1 Y 1 B MET 645 ? A MET 645 
245 1 Y 1 B MET 646 ? A MET 646 
246 1 Y 1 B ASP 647 ? A ASP 647 
247 1 Y 1 B GLN 648 ? A GLN 648 
248 1 Y 1 B ASP 649 ? A ASP 649 
249 1 Y 1 B ASP 650 ? A ASP 650 
250 1 Y 1 B GLY 651 ? A GLY 651 
251 1 Y 1 B VAL 652 ? A VAL 652 
252 1 Y 1 B ARG 653 ? A ARG 653 
253 1 Y 1 B ASN 654 ? A ASN 654 
254 1 Y 1 B ARG 655 ? A ARG 655 
255 1 Y 1 B GLN 656 ? A GLN 656 
256 1 Y 1 B LYS 657 ? A LYS 657 
257 1 Y 1 B ASN 658 ? A ASN 658 
258 1 Y 1 B ARG 659 ? A ARG 659 
259 1 Y 1 B SER 660 ? A SER 660 
260 1 Y 1 B TRP 661 ? A TRP 661 
261 1 Y 1 B LYS 662 ? A LYS 662 
262 1 Y 1 B TYR 663 ? A TYR 663 
263 1 Y 1 B ASN 664 ? A ASN 664 
264 1 Y 1 B GLN 665 ? A GLN 665 
265 1 Y 1 B SER 666 ? A SER 666 
266 1 Y 1 B ILE 667 ? A ILE 667 
267 1 Y 1 B SER 668 ? A SER 668 
268 1 Y 1 B LEU 669 ? A LEU 669 
269 1 Y 1 B ARG 670 ? A ARG 670 
270 1 Y 1 B ARG 671 ? A ARG 671 
271 1 Y 1 B PRO 672 ? A PRO 672 
272 1 Y 1 B ARG 673 ? A ARG 673 
273 1 Y 1 B LEU 674 ? A LEU 674 
274 1 Y 1 B ALA 675 ? A ALA 675 
275 1 Y 1 B SER 676 ? A SER 676 
276 1 Y 1 B GLN 677 ? A GLN 677 
277 1 Y 1 B SER 678 ? A SER 678 
278 1 Y 1 B LYS 679 ? A LYS 679 
279 1 Y 1 B ALA 680 ? A ALA 680 
280 1 Y 1 B ARG 681 ? A ARG 681 
281 1 Y 1 B ASP 682 ? A ASP 682 
282 1 Y 1 B THR 683 ? A THR 683 
283 1 Y 1 B LYS 684 ? A LYS 684 
284 1 Y 1 B VAL 685 ? A VAL 685 
285 1 Y 1 B LEU 686 ? A LEU 686 
286 1 Y 1 B ILE 687 ? A ILE 687 
287 1 Y 1 B GLU 688 ? A GLU 688 
288 1 Y 1 B ASP 689 ? A ASP 689 
289 1 Y 1 B THR 690 ? A THR 690 
290 1 Y 1 B ASP 691 ? A ASP 691 
291 1 Y 1 B ASP 692 ? A ASP 692 
292 1 Y 1 B GLU 693 ? A GLU 693 
293 1 Y 1 B ALA 694 ? A ALA 694 
294 1 Y 1 B ASN 695 ? A ASN 695 
295 1 Y 1 B THR 696 ? A THR 696 
296 1 Y 1 B SER 697 ? A SER 697 
297 1 Y 1 B ARG 698 ? A ARG 698 
298 1 Y 1 B GLU 699 ? A GLU 699 
299 1 Y 1 B ASN 700 ? A ASN 700 
300 1 Y 1 B LEU 701 ? A LEU 701 
301 1 Y 1 B TYR 702 ? A TYR 702 
302 1 Y 1 B PHE 703 ? A PHE 703 
303 1 Y 1 B GLN 704 ? A GLN 704 
304 1 Y 1 A MET 1   ? B MET 1   
305 1 Y 1 A LYS 2   ? B LYS 2   
306 1 Y 1 A PHE 3   ? B PHE 3   
307 1 Y 1 A ALA 4   ? B ALA 4   
308 1 Y 1 A GLU 5   ? B GLU 5   
309 1 Y 1 A HIS 6   ? B HIS 6   
310 1 Y 1 A LEU 7   ? B LEU 7   
311 1 Y 1 A SER 8   ? B SER 8   
312 1 Y 1 A ALA 9   ? B ALA 9   
313 1 Y 1 A HIS 10  ? B HIS 10  
314 1 Y 1 A ILE 11  ? B ILE 11  
315 1 Y 1 A THR 12  ? B THR 12  
316 1 Y 1 A PRO 13  ? B PRO 13  
317 1 Y 1 A GLU 14  ? B GLU 14  
318 1 Y 1 A TRP 15  ? B TRP 15  
319 1 Y 1 A ARG 16  ? B ARG 16  
320 1 Y 1 A LYS 17  ? B LYS 17  
321 1 Y 1 A GLN 18  ? B GLN 18  
322 1 Y 1 A TYR 19  ? B TYR 19  
323 1 Y 1 A ILE 20  ? B ILE 20  
324 1 Y 1 A GLN 21  ? B GLN 21  
325 1 Y 1 A TYR 22  ? B TYR 22  
326 1 Y 1 A GLU 23  ? B GLU 23  
327 1 Y 1 A ALA 24  ? B ALA 24  
328 1 Y 1 A PHE 25  ? B PHE 25  
329 1 Y 1 A LYS 26  ? B LYS 26  
330 1 Y 1 A ASP 27  ? B ASP 27  
331 1 Y 1 A MET 28  ? B MET 28  
332 1 Y 1 A LEU 29  ? B LEU 29  
333 1 Y 1 A TYR 30  ? B TYR 30  
334 1 Y 1 A SER 31  ? B SER 31  
335 1 Y 1 A ALA 32  ? B ALA 32  
336 1 Y 1 A GLN 33  ? B GLN 33  
337 1 Y 1 A ASP 34  ? B ASP 34  
338 1 Y 1 A GLN 35  ? B GLN 35  
339 1 Y 1 A ALA 36  ? B ALA 36  
340 1 Y 1 A PRO 37  ? B PRO 37  
341 1 Y 1 A SER 38  ? B SER 38  
342 1 Y 1 A VAL 39  ? B VAL 39  
343 1 Y 1 A GLU 40  ? B GLU 40  
344 1 Y 1 A VAL 41  ? B VAL 41  
345 1 Y 1 A THR 42  ? B THR 42  
346 1 Y 1 A ASP 43  ? B ASP 43  
347 1 Y 1 A GLU 44  ? B GLU 44  
348 1 Y 1 A ASP 45  ? B ASP 45  
349 1 Y 1 A THR 46  ? B THR 46  
350 1 Y 1 A VAL 47  ? B VAL 47  
351 1 Y 1 A LYS 48  ? B LYS 48  
352 1 Y 1 A ARG 49  ? B ARG 49  
353 1 Y 1 A TYR 50  ? B TYR 50  
354 1 Y 1 A PHE 51  ? B PHE 51  
355 1 Y 1 A ALA 52  ? B ALA 52  
356 1 Y 1 A LYS 53  ? B LYS 53  
357 1 Y 1 A PHE 54  ? B PHE 54  
358 1 Y 1 A GLU 55  ? B GLU 55  
359 1 Y 1 A GLU 56  ? B GLU 56  
360 1 Y 1 A LYS 57  ? B LYS 57  
361 1 Y 1 A PHE 58  ? B PHE 58  
362 1 Y 1 A PHE 59  ? B PHE 59  
363 1 Y 1 A GLN 60  ? B GLN 60  
364 1 Y 1 A THR 61  ? B THR 61  
365 1 Y 1 A CYS 62  ? B CYS 62  
366 1 Y 1 A GLU 63  ? B GLU 63  
367 1 Y 1 A LYS 64  ? B LYS 64  
368 1 Y 1 A GLU 65  ? B GLU 65  
369 1 Y 1 A LEU 66  ? B LEU 66  
370 1 Y 1 A ALA 67  ? B ALA 67  
371 1 Y 1 A LYS 68  ? B LYS 68  
372 1 Y 1 A ILE 69  ? B ILE 69  
373 1 Y 1 A ASN 70  ? B ASN 70  
374 1 Y 1 A THR 71  ? B THR 71  
375 1 Y 1 A PHE 72  ? B PHE 72  
376 1 Y 1 A TYR 73  ? B TYR 73  
377 1 Y 1 A SER 74  ? B SER 74  
378 1 Y 1 A GLU 75  ? B GLU 75  
379 1 Y 1 A LYS 76  ? B LYS 76  
380 1 Y 1 A LEU 77  ? B LEU 77  
381 1 Y 1 A ALA 78  ? B ALA 78  
382 1 Y 1 A GLU 79  ? B GLU 79  
383 1 Y 1 A ALA 80  ? B ALA 80  
384 1 Y 1 A GLN 81  ? B GLN 81  
385 1 Y 1 A ARG 82  ? B ARG 82  
386 1 Y 1 A ARG 83  ? B ARG 83  
387 1 Y 1 A PHE 84  ? B PHE 84  
388 1 Y 1 A ALA 85  ? B ALA 85  
389 1 Y 1 A THR 86  ? B THR 86  
390 1 Y 1 A LEU 87  ? B LEU 87  
391 1 Y 1 A GLN 88  ? B GLN 88  
392 1 Y 1 A ASN 89  ? B ASN 89  
393 1 Y 1 A GLU 90  ? B GLU 90  
394 1 Y 1 A LEU 91  ? B LEU 91  
395 1 Y 1 A GLN 92  ? B GLN 92  
396 1 Y 1 A SER 93  ? B SER 93  
397 1 Y 1 A SER 94  ? B SER 94  
398 1 Y 1 A LEU 95  ? B LEU 95  
399 1 Y 1 A ASP 96  ? B ASP 96  
400 1 Y 1 A ALA 97  ? B ALA 97  
401 1 Y 1 A GLN 98  ? B GLN 98  
402 1 Y 1 A LYS 99  ? B LYS 99  
403 1 Y 1 A GLU 100 ? B GLU 100 
404 1 Y 1 A SER 101 ? B SER 101 
405 1 Y 1 A THR 102 ? B THR 102 
406 1 Y 1 A GLY 103 ? B GLY 103 
407 1 Y 1 A VAL 104 ? B VAL 104 
408 1 Y 1 A THR 105 ? B THR 105 
409 1 Y 1 A THR 106 ? B THR 106 
410 1 Y 1 A LEU 107 ? B LEU 107 
411 1 Y 1 A ARG 108 ? B ARG 108 
412 1 Y 1 A GLN 109 ? B GLN 109 
413 1 Y 1 A ARG 110 ? B ARG 110 
414 1 Y 1 A ARG 111 ? B ARG 111 
415 1 Y 1 A LYS 112 ? B LYS 112 
416 1 Y 1 A PRO 113 ? B PRO 113 
417 1 Y 1 A VAL 114 ? B VAL 114 
418 1 Y 1 A PHE 115 ? B PHE 115 
419 1 Y 1 A HIS 116 ? B HIS 116 
420 1 Y 1 A LEU 117 ? B LEU 117 
421 1 Y 1 A SER 118 ? B SER 118 
422 1 Y 1 A HIS 119 ? B HIS 119 
423 1 Y 1 A GLU 120 ? B GLU 120 
424 1 Y 1 A GLU 121 ? B GLU 121 
425 1 Y 1 A ARG 122 ? B ARG 122 
426 1 Y 1 A VAL 123 ? B VAL 123 
427 1 Y 1 A GLN 124 ? B GLN 124 
428 1 Y 1 A HIS 125 ? B HIS 125 
429 1 Y 1 A ARG 126 ? B ARG 126 
430 1 Y 1 A ASN 127 ? B ASN 127 
431 1 Y 1 A ILE 128 ? B ILE 128 
432 1 Y 1 A LYS 129 ? B LYS 129 
433 1 Y 1 A ASP 130 ? B ASP 130 
434 1 Y 1 A LEU 131 ? B LEU 131 
435 1 Y 1 A LYS 132 ? B LYS 132 
436 1 Y 1 A LEU 133 ? B LEU 133 
437 1 Y 1 A ALA 134 ? B ALA 134 
438 1 Y 1 A PHE 135 ? B PHE 135 
439 1 Y 1 A SER 136 ? B SER 136 
440 1 Y 1 A GLU 137 ? B GLU 137 
441 1 Y 1 A PHE 138 ? B PHE 138 
442 1 Y 1 A TYR 139 ? B TYR 139 
443 1 Y 1 A LEU 140 ? B LEU 140 
444 1 Y 1 A SER 141 ? B SER 141 
445 1 Y 1 A LEU 142 ? B LEU 142 
446 1 Y 1 A ILE 143 ? B ILE 143 
447 1 Y 1 A LEU 144 ? B LEU 144 
448 1 Y 1 A LEU 145 ? B LEU 145 
449 1 Y 1 A GLN 146 ? B GLN 146 
450 1 Y 1 A ASN 147 ? B ASN 147 
451 1 Y 1 A TYR 148 ? B TYR 148 
452 1 Y 1 A GLN 149 ? B GLN 149 
453 1 Y 1 A ASN 150 ? B ASN 150 
454 1 Y 1 A LEU 151 ? B LEU 151 
455 1 Y 1 A ASN 152 ? B ASN 152 
456 1 Y 1 A PHE 153 ? B PHE 153 
457 1 Y 1 A THR 154 ? B THR 154 
458 1 Y 1 A GLY 155 ? B GLY 155 
459 1 Y 1 A PHE 156 ? B PHE 156 
460 1 Y 1 A ARG 157 ? B ARG 157 
461 1 Y 1 A LYS 158 ? B LYS 158 
462 1 Y 1 A ILE 159 ? B ILE 159 
463 1 Y 1 A LEU 160 ? B LEU 160 
464 1 Y 1 A LYS 161 ? B LYS 161 
465 1 Y 1 A LYS 162 ? B LYS 162 
466 1 Y 1 A HIS 163 ? B HIS 163 
467 1 Y 1 A ASP 164 ? B ASP 164 
468 1 Y 1 A LYS 165 ? B LYS 165 
469 1 Y 1 A ILE 166 ? B ILE 166 
470 1 Y 1 A LEU 167 ? B LEU 167 
471 1 Y 1 A GLU 168 ? B GLU 168 
472 1 Y 1 A THR 169 ? B THR 169 
473 1 Y 1 A SER 170 ? B SER 170 
474 1 Y 1 A ARG 171 ? B ARG 171 
475 1 Y 1 A GLY 172 ? B GLY 172 
476 1 Y 1 A ALA 173 ? B ALA 173 
477 1 Y 1 A ASP 174 ? B ASP 174 
478 1 Y 1 A TRP 175 ? B TRP 175 
479 1 Y 1 A ARG 176 ? B ARG 176 
480 1 Y 1 A VAL 177 ? B VAL 177 
481 1 Y 1 A ALA 178 ? B ALA 178 
482 1 Y 1 A HIS 179 ? B HIS 179 
483 1 Y 1 A VAL 180 ? B VAL 180 
484 1 Y 1 A GLU 181 ? B GLU 181 
485 1 Y 1 A VAL 182 ? B VAL 182 
486 1 Y 1 A ALA 183 ? B ALA 183 
487 1 Y 1 A PRO 184 ? B PRO 184 
488 1 Y 1 A PHE 185 ? B PHE 185 
489 1 Y 1 A TYR 186 ? B TYR 186 
490 1 Y 1 A THR 187 ? B THR 187 
491 1 Y 1 A CYS 188 ? B CYS 188 
492 1 Y 1 A LYS 189 ? B LYS 189 
493 1 Y 1 A LYS 190 ? B LYS 190 
494 1 Y 1 A ILE 191 ? B ILE 191 
495 1 Y 1 A ASN 192 ? B ASN 192 
496 1 Y 1 A GLN 193 ? B GLN 193 
497 1 Y 1 A LEU 194 ? B LEU 194 
498 1 Y 1 A ILE 195 ? B ILE 195 
499 1 Y 1 A SER 196 ? B SER 196 
500 1 Y 1 A GLU 197 ? B GLU 197 
501 1 Y 1 A THR 198 ? B THR 198 
502 1 Y 1 A GLU 199 ? B GLU 199 
503 1 Y 1 A ALA 200 ? B ALA 200 
504 1 Y 1 A VAL 201 ? B VAL 201 
505 1 Y 1 A VAL 202 ? B VAL 202 
506 1 Y 1 A THR 203 ? B THR 203 
507 1 Y 1 A ASN 204 ? B ASN 204 
508 1 Y 1 A GLU 205 ? B GLU 205 
509 1 Y 1 A LEU 206 ? B LEU 206 
510 1 Y 1 A GLU 207 ? B GLU 207 
511 1 Y 1 A ASP 208 ? B ASP 208 
512 1 Y 1 A GLY 209 ? B GLY 209 
513 1 Y 1 A ASP 210 ? B ASP 210 
514 1 Y 1 A ARG 211 ? B ARG 211 
515 1 Y 1 A GLN 212 ? B GLN 212 
516 1 Y 1 A LYS 213 ? B LYS 213 
517 1 Y 1 A ALA 214 ? B ALA 214 
518 1 Y 1 A MET 215 ? B MET 215 
519 1 Y 1 A LYS 216 ? B LYS 216 
520 1 Y 1 A ARG 217 ? B ARG 217 
521 1 Y 1 A LEU 218 ? B LEU 218 
522 1 Y 1 A ARG 219 ? B ARG 219 
523 1 Y 1 A VAL 220 ? B VAL 220 
524 1 Y 1 A PRO 221 ? B PRO 221 
525 1 Y 1 A PRO 222 ? B PRO 222 
526 1 Y 1 A LEU 223 ? B LEU 223 
527 1 Y 1 A GLY 224 ? B GLY 224 
528 1 Y 1 A ALA 225 ? B ALA 225 
529 1 Y 1 A ARG 627 ? B ARG 627 
530 1 Y 1 A ASP 628 ? B ASP 628 
531 1 Y 1 A ILE 629 ? B ILE 629 
532 1 Y 1 A SER 630 ? B SER 630 
533 1 Y 1 A VAL 631 ? B VAL 631 
534 1 Y 1 A ALA 632 ? B ALA 632 
535 1 Y 1 A PRO 633 ? B PRO 633 
536 1 Y 1 A LEU 634 ? B LEU 634 
537 1 Y 1 A ASN 635 ? B ASN 635 
538 1 Y 1 A ALA 636 ? B ALA 636 
539 1 Y 1 A ASP 637 ? B ASP 637 
540 1 Y 1 A ASP 638 ? B ASP 638 
541 1 Y 1 A GLN 639 ? B GLN 639 
542 1 Y 1 A THR 640 ? B THR 640 
543 1 Y 1 A LEU 641 ? B LEU 641 
544 1 Y 1 A LEU 642 ? B LEU 642 
545 1 Y 1 A GLU 643 ? B GLU 643 
546 1 Y 1 A GLN 644 ? B GLN 644 
547 1 Y 1 A MET 645 ? B MET 645 
548 1 Y 1 A MET 646 ? B MET 646 
549 1 Y 1 A ASP 647 ? B ASP 647 
550 1 Y 1 A GLN 648 ? B GLN 648 
551 1 Y 1 A ASP 649 ? B ASP 649 
552 1 Y 1 A ASP 650 ? B ASP 650 
553 1 Y 1 A GLY 651 ? B GLY 651 
554 1 Y 1 A VAL 652 ? B VAL 652 
555 1 Y 1 A ARG 653 ? B ARG 653 
556 1 Y 1 A ASN 654 ? B ASN 654 
557 1 Y 1 A ARG 655 ? B ARG 655 
558 1 Y 1 A GLN 656 ? B GLN 656 
559 1 Y 1 A LYS 657 ? B LYS 657 
560 1 Y 1 A ASN 658 ? B ASN 658 
561 1 Y 1 A ARG 659 ? B ARG 659 
562 1 Y 1 A SER 660 ? B SER 660 
563 1 Y 1 A TRP 661 ? B TRP 661 
564 1 Y 1 A LYS 662 ? B LYS 662 
565 1 Y 1 A TYR 663 ? B TYR 663 
566 1 Y 1 A ASN 664 ? B ASN 664 
567 1 Y 1 A GLN 665 ? B GLN 665 
568 1 Y 1 A SER 666 ? B SER 666 
569 1 Y 1 A ILE 667 ? B ILE 667 
570 1 Y 1 A SER 668 ? B SER 668 
571 1 Y 1 A LEU 669 ? B LEU 669 
572 1 Y 1 A ARG 670 ? B ARG 670 
573 1 Y 1 A ARG 671 ? B ARG 671 
574 1 Y 1 A PRO 672 ? B PRO 672 
575 1 Y 1 A ARG 673 ? B ARG 673 
576 1 Y 1 A LEU 674 ? B LEU 674 
577 1 Y 1 A ALA 675 ? B ALA 675 
578 1 Y 1 A SER 676 ? B SER 676 
579 1 Y 1 A GLN 677 ? B GLN 677 
580 1 Y 1 A SER 678 ? B SER 678 
581 1 Y 1 A LYS 679 ? B LYS 679 
582 1 Y 1 A ALA 680 ? B ALA 680 
583 1 Y 1 A ARG 681 ? B ARG 681 
584 1 Y 1 A ASP 682 ? B ASP 682 
585 1 Y 1 A THR 683 ? B THR 683 
586 1 Y 1 A LYS 684 ? B LYS 684 
587 1 Y 1 A VAL 685 ? B VAL 685 
588 1 Y 1 A LEU 686 ? B LEU 686 
589 1 Y 1 A ILE 687 ? B ILE 687 
590 1 Y 1 A GLU 688 ? B GLU 688 
591 1 Y 1 A ASP 689 ? B ASP 689 
592 1 Y 1 A THR 690 ? B THR 690 
593 1 Y 1 A ASP 691 ? B ASP 691 
594 1 Y 1 A ASP 692 ? B ASP 692 
595 1 Y 1 A GLU 693 ? B GLU 693 
596 1 Y 1 A ALA 694 ? B ALA 694 
597 1 Y 1 A ASN 695 ? B ASN 695 
598 1 Y 1 A THR 696 ? B THR 696 
599 1 Y 1 A SER 697 ? B SER 697 
600 1 Y 1 A ARG 698 ? B ARG 698 
601 1 Y 1 A GLU 699 ? B GLU 699 
602 1 Y 1 A ASN 700 ? B ASN 700 
603 1 Y 1 A LEU 701 ? B LEU 701 
604 1 Y 1 A TYR 702 ? B TYR 702 
605 1 Y 1 A PHE 703 ? B PHE 703 
606 1 Y 1 A GLN 704 ? B GLN 704 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
3PE P    P N N 1   
3PE N    N N N 2   
3PE O11  O N N 3   
3PE O12  O N N 4   
3PE O13  O N N 5   
3PE O14  O N N 6   
3PE C11  C N N 7   
3PE C12  C N N 8   
3PE C1   C N N 9   
3PE C2   C N R 10  
3PE C3   C N N 11  
3PE O31  O N N 12  
3PE O32  O N N 13  
3PE C31  C N N 14  
3PE C32  C N N 15  
3PE C33  C N N 16  
3PE C34  C N N 17  
3PE C35  C N N 18  
3PE C36  C N N 19  
3PE C37  C N N 20  
3PE C38  C N N 21  
3PE C39  C N N 22  
3PE C3A  C N N 23  
3PE C3B  C N N 24  
3PE C3C  C N N 25  
3PE C3D  C N N 26  
3PE C3E  C N N 27  
3PE C3F  C N N 28  
3PE C3G  C N N 29  
3PE C3H  C N N 30  
3PE C3I  C N N 31  
3PE O21  O N N 32  
3PE O22  O N N 33  
3PE C21  C N N 34  
3PE C22  C N N 35  
3PE C23  C N N 36  
3PE C24  C N N 37  
3PE C25  C N N 38  
3PE C26  C N N 39  
3PE C27  C N N 40  
3PE C28  C N N 41  
3PE C29  C N N 42  
3PE C2A  C N N 43  
3PE C2B  C N N 44  
3PE C2C  C N N 45  
3PE C2D  C N N 46  
3PE C2E  C N N 47  
3PE C2F  C N N 48  
3PE C2G  C N N 49  
3PE C2H  C N N 50  
3PE C2I  C N N 51  
3PE HN1  H N N 52  
3PE HN2  H N N 53  
3PE H111 H N N 54  
3PE H112 H N N 55  
3PE H121 H N N 56  
3PE H122 H N N 57  
3PE H11  H N N 58  
3PE H12  H N N 59  
3PE H2   H N N 60  
3PE H31  H N N 61  
3PE H32  H N N 62  
3PE H321 H N N 63  
3PE H322 H N N 64  
3PE H331 H N N 65  
3PE H332 H N N 66  
3PE H341 H N N 67  
3PE H342 H N N 68  
3PE H351 H N N 69  
3PE H352 H N N 70  
3PE H361 H N N 71  
3PE H362 H N N 72  
3PE H371 H N N 73  
3PE H372 H N N 74  
3PE H381 H N N 75  
3PE H382 H N N 76  
3PE H391 H N N 77  
3PE H392 H N N 78  
3PE H3A1 H N N 79  
3PE H3A2 H N N 80  
3PE H3B1 H N N 81  
3PE H3B2 H N N 82  
3PE H3C1 H N N 83  
3PE H3C2 H N N 84  
3PE H3D1 H N N 85  
3PE H3D2 H N N 86  
3PE H3E1 H N N 87  
3PE H3E2 H N N 88  
3PE H3F1 H N N 89  
3PE H3F2 H N N 90  
3PE H3G1 H N N 91  
3PE H3G2 H N N 92  
3PE H3H1 H N N 93  
3PE H3H2 H N N 94  
3PE H3I1 H N N 95  
3PE H3I2 H N N 96  
3PE H3I3 H N N 97  
3PE H221 H N N 98  
3PE H222 H N N 99  
3PE H231 H N N 100 
3PE H232 H N N 101 
3PE H241 H N N 102 
3PE H242 H N N 103 
3PE H251 H N N 104 
3PE H252 H N N 105 
3PE H261 H N N 106 
3PE H262 H N N 107 
3PE H271 H N N 108 
3PE H272 H N N 109 
3PE H281 H N N 110 
3PE H282 H N N 111 
3PE H291 H N N 112 
3PE H292 H N N 113 
3PE H2A1 H N N 114 
3PE H2A2 H N N 115 
3PE H2B1 H N N 116 
3PE H2B2 H N N 117 
3PE H2C1 H N N 118 
3PE H2C2 H N N 119 
3PE H2D1 H N N 120 
3PE H2D2 H N N 121 
3PE H2E1 H N N 122 
3PE H2E2 H N N 123 
3PE H2F1 H N N 124 
3PE H2F2 H N N 125 
3PE H2G1 H N N 126 
3PE H2G2 H N N 127 
3PE H2H1 H N N 128 
3PE H2H2 H N N 129 
3PE H2I1 H N N 130 
3PE H2I2 H N N 131 
3PE H2I3 H N N 132 
3PE H1   H N N 133 
ACD C1   C N N 134 
ACD C2   C N N 135 
ACD C3   C N N 136 
ACD C4   C N N 137 
ACD C5   C N N 138 
ACD C6   C N N 139 
ACD C7   C N N 140 
ACD C8   C N N 141 
ACD C9   C N N 142 
ACD C10  C N N 143 
ACD C11  C N N 144 
ACD C12  C N N 145 
ACD C13  C N N 146 
ACD C14  C N N 147 
ACD C15  C N N 148 
ACD C16  C N N 149 
ACD C17  C N N 150 
ACD C18  C N N 151 
ACD C19  C N N 152 
ACD C20  C N N 153 
ACD O1   O N N 154 
ACD O2   O N N 155 
ACD H21  H N N 156 
ACD H22  H N N 157 
ACD H31  H N N 158 
ACD H32  H N N 159 
ACD H41  H N N 160 
ACD H42  H N N 161 
ACD H5   H N N 162 
ACD H6   H N N 163 
ACD H71  H N N 164 
ACD H72  H N N 165 
ACD H8   H N N 166 
ACD H9   H N N 167 
ACD H101 H N N 168 
ACD H102 H N N 169 
ACD H11  H N N 170 
ACD H12  H N N 171 
ACD H131 H N N 172 
ACD H132 H N N 173 
ACD H14  H N N 174 
ACD H15  H N N 175 
ACD H161 H N N 176 
ACD H162 H N N 177 
ACD H171 H N N 178 
ACD H172 H N N 179 
ACD H181 H N N 180 
ACD H182 H N N 181 
ACD H191 H N N 182 
ACD H192 H N N 183 
ACD H201 H N N 184 
ACD H202 H N N 185 
ACD H203 H N N 186 
ACD HO2  H N N 187 
ALA N    N N N 188 
ALA CA   C N S 189 
ALA C    C N N 190 
ALA O    O N N 191 
ALA CB   C N N 192 
ALA OXT  O N N 193 
ALA H    H N N 194 
ALA H2   H N N 195 
ALA HA   H N N 196 
ALA HB1  H N N 197 
ALA HB2  H N N 198 
ALA HB3  H N N 199 
ALA HXT  H N N 200 
ARG N    N N N 201 
ARG CA   C N S 202 
ARG C    C N N 203 
ARG O    O N N 204 
ARG CB   C N N 205 
ARG CG   C N N 206 
ARG CD   C N N 207 
ARG NE   N N N 208 
ARG CZ   C N N 209 
ARG NH1  N N N 210 
ARG NH2  N N N 211 
ARG OXT  O N N 212 
ARG H    H N N 213 
ARG H2   H N N 214 
ARG HA   H N N 215 
ARG HB2  H N N 216 
ARG HB3  H N N 217 
ARG HG2  H N N 218 
ARG HG3  H N N 219 
ARG HD2  H N N 220 
ARG HD3  H N N 221 
ARG HE   H N N 222 
ARG HH11 H N N 223 
ARG HH12 H N N 224 
ARG HH21 H N N 225 
ARG HH22 H N N 226 
ARG HXT  H N N 227 
ASN N    N N N 228 
ASN CA   C N S 229 
ASN C    C N N 230 
ASN O    O N N 231 
ASN CB   C N N 232 
ASN CG   C N N 233 
ASN OD1  O N N 234 
ASN ND2  N N N 235 
ASN OXT  O N N 236 
ASN H    H N N 237 
ASN H2   H N N 238 
ASN HA   H N N 239 
ASN HB2  H N N 240 
ASN HB3  H N N 241 
ASN HD21 H N N 242 
ASN HD22 H N N 243 
ASN HXT  H N N 244 
ASP N    N N N 245 
ASP CA   C N S 246 
ASP C    C N N 247 
ASP O    O N N 248 
ASP CB   C N N 249 
ASP CG   C N N 250 
ASP OD1  O N N 251 
ASP OD2  O N N 252 
ASP OXT  O N N 253 
ASP H    H N N 254 
ASP H2   H N N 255 
ASP HA   H N N 256 
ASP HB2  H N N 257 
ASP HB3  H N N 258 
ASP HD2  H N N 259 
ASP HXT  H N N 260 
CLR C1   C N N 261 
CLR C2   C N N 262 
CLR C3   C N S 263 
CLR C4   C N N 264 
CLR C5   C N N 265 
CLR C6   C N N 266 
CLR C7   C N N 267 
CLR C8   C N S 268 
CLR C9   C N S 269 
CLR C10  C N R 270 
CLR C11  C N N 271 
CLR C12  C N N 272 
CLR C13  C N R 273 
CLR C14  C N S 274 
CLR C15  C N N 275 
CLR C16  C N N 276 
CLR C17  C N R 277 
CLR C18  C N N 278 
CLR C19  C N N 279 
CLR C20  C N R 280 
CLR C21  C N N 281 
CLR C22  C N N 282 
CLR C23  C N N 283 
CLR C24  C N N 284 
CLR C25  C N N 285 
CLR C26  C N N 286 
CLR C27  C N N 287 
CLR O1   O N N 288 
CLR H11  H N N 289 
CLR H12  H N N 290 
CLR H21  H N N 291 
CLR H22  H N N 292 
CLR H3   H N N 293 
CLR H41  H N N 294 
CLR H42  H N N 295 
CLR H6   H N N 296 
CLR H71  H N N 297 
CLR H72  H N N 298 
CLR H8   H N N 299 
CLR H9   H N N 300 
CLR H111 H N N 301 
CLR H112 H N N 302 
CLR H121 H N N 303 
CLR H122 H N N 304 
CLR H14  H N N 305 
CLR H151 H N N 306 
CLR H152 H N N 307 
CLR H161 H N N 308 
CLR H162 H N N 309 
CLR H17  H N N 310 
CLR H181 H N N 311 
CLR H182 H N N 312 
CLR H183 H N N 313 
CLR H191 H N N 314 
CLR H192 H N N 315 
CLR H193 H N N 316 
CLR H20  H N N 317 
CLR H211 H N N 318 
CLR H212 H N N 319 
CLR H213 H N N 320 
CLR H221 H N N 321 
CLR H222 H N N 322 
CLR H231 H N N 323 
CLR H232 H N N 324 
CLR H241 H N N 325 
CLR H242 H N N 326 
CLR H25  H N N 327 
CLR H261 H N N 328 
CLR H262 H N N 329 
CLR H263 H N N 330 
CLR H271 H N N 331 
CLR H272 H N N 332 
CLR H273 H N N 333 
CLR H1   H N N 334 
CYS N    N N N 335 
CYS CA   C N R 336 
CYS C    C N N 337 
CYS O    O N N 338 
CYS CB   C N N 339 
CYS SG   S N N 340 
CYS OXT  O N N 341 
CYS H    H N N 342 
CYS H2   H N N 343 
CYS HA   H N N 344 
CYS HB2  H N N 345 
CYS HB3  H N N 346 
CYS HG   H N N 347 
CYS HXT  H N N 348 
GLN N    N N N 349 
GLN CA   C N S 350 
GLN C    C N N 351 
GLN O    O N N 352 
GLN CB   C N N 353 
GLN CG   C N N 354 
GLN CD   C N N 355 
GLN OE1  O N N 356 
GLN NE2  N N N 357 
GLN OXT  O N N 358 
GLN H    H N N 359 
GLN H2   H N N 360 
GLN HA   H N N 361 
GLN HB2  H N N 362 
GLN HB3  H N N 363 
GLN HG2  H N N 364 
GLN HG3  H N N 365 
GLN HE21 H N N 366 
GLN HE22 H N N 367 
GLN HXT  H N N 368 
GLU N    N N N 369 
GLU CA   C N S 370 
GLU C    C N N 371 
GLU O    O N N 372 
GLU CB   C N N 373 
GLU CG   C N N 374 
GLU CD   C N N 375 
GLU OE1  O N N 376 
GLU OE2  O N N 377 
GLU OXT  O N N 378 
GLU H    H N N 379 
GLU H2   H N N 380 
GLU HA   H N N 381 
GLU HB2  H N N 382 
GLU HB3  H N N 383 
GLU HG2  H N N 384 
GLU HG3  H N N 385 
GLU HE2  H N N 386 
GLU HXT  H N N 387 
GLY N    N N N 388 
GLY CA   C N N 389 
GLY C    C N N 390 
GLY O    O N N 391 
GLY OXT  O N N 392 
GLY H    H N N 393 
GLY H2   H N N 394 
GLY HA2  H N N 395 
GLY HA3  H N N 396 
GLY HXT  H N N 397 
HIS N    N N N 398 
HIS CA   C N S 399 
HIS C    C N N 400 
HIS O    O N N 401 
HIS CB   C N N 402 
HIS CG   C Y N 403 
HIS ND1  N Y N 404 
HIS CD2  C Y N 405 
HIS CE1  C Y N 406 
HIS NE2  N Y N 407 
HIS OXT  O N N 408 
HIS H    H N N 409 
HIS H2   H N N 410 
HIS HA   H N N 411 
HIS HB2  H N N 412 
HIS HB3  H N N 413 
HIS HD1  H N N 414 
HIS HD2  H N N 415 
HIS HE1  H N N 416 
HIS HE2  H N N 417 
HIS HXT  H N N 418 
HOH O    O N N 419 
HOH H1   H N N 420 
HOH H2   H N N 421 
ILE N    N N N 422 
ILE CA   C N S 423 
ILE C    C N N 424 
ILE O    O N N 425 
ILE CB   C N S 426 
ILE CG1  C N N 427 
ILE CG2  C N N 428 
ILE CD1  C N N 429 
ILE OXT  O N N 430 
ILE H    H N N 431 
ILE H2   H N N 432 
ILE HA   H N N 433 
ILE HB   H N N 434 
ILE HG12 H N N 435 
ILE HG13 H N N 436 
ILE HG21 H N N 437 
ILE HG22 H N N 438 
ILE HG23 H N N 439 
ILE HD11 H N N 440 
ILE HD12 H N N 441 
ILE HD13 H N N 442 
ILE HXT  H N N 443 
LEU N    N N N 444 
LEU CA   C N S 445 
LEU C    C N N 446 
LEU O    O N N 447 
LEU CB   C N N 448 
LEU CG   C N N 449 
LEU CD1  C N N 450 
LEU CD2  C N N 451 
LEU OXT  O N N 452 
LEU H    H N N 453 
LEU H2   H N N 454 
LEU HA   H N N 455 
LEU HB2  H N N 456 
LEU HB3  H N N 457 
LEU HG   H N N 458 
LEU HD11 H N N 459 
LEU HD12 H N N 460 
LEU HD13 H N N 461 
LEU HD21 H N N 462 
LEU HD22 H N N 463 
LEU HD23 H N N 464 
LEU HXT  H N N 465 
LPE C1   C N N 466 
LPE O1   O N N 467 
LPE C2   C N R 468 
LPE O2H  O N N 469 
LPE C3   C N N 470 
LPE C11  C N N 471 
LPE C12  C N N 472 
LPE O3   O N N 473 
LPE P    P N R 474 
LPE O31  O N N 475 
LPE O32  O N N 476 
LPE O33  O N N 477 
LPE C31  C N N 478 
LPE C32  C N N 479 
LPE N    N N N 480 
LPE C1N  C N N 481 
LPE C2N  C N N 482 
LPE C3N  C N N 483 
LPE C13  C N N 484 
LPE C14  C N N 485 
LPE C15  C N N 486 
LPE C16  C N N 487 
LPE C17  C N N 488 
LPE C18  C N N 489 
LPE C19  C N N 490 
LPE C20  C N N 491 
LPE C21  C N N 492 
LPE C22  C N N 493 
LPE C23  C N N 494 
LPE C24  C N N 495 
LPE C25  C N N 496 
LPE C26  C N N 497 
LPE C27  C N N 498 
LPE C28  C N N 499 
LPE H11  H N N 500 
LPE H12  H N N 501 
LPE H21  H N N 502 
LPE HO21 H N N 503 
LPE H31  H N N 504 
LPE H32  H N N 505 
LPE H111 H N N 506 
LPE H112 H N N 507 
LPE H121 H N N 508 
LPE H122 H N N 509 
LPE HO31 H N N 510 
LPE H311 H N N 511 
LPE H312 H N N 512 
LPE H321 H N N 513 
LPE H322 H N N 514 
LPE H1N1 H N N 515 
LPE H1N2 H N N 516 
LPE H1N3 H N N 517 
LPE H2N1 H N N 518 
LPE H2N2 H N N 519 
LPE H2N3 H N N 520 
LPE H3N1 H N N 521 
LPE H3N2 H N N 522 
LPE H3N3 H N N 523 
LPE H131 H N N 524 
LPE H132 H N N 525 
LPE H141 H N N 526 
LPE H142 H N N 527 
LPE H151 H N N 528 
LPE H152 H N N 529 
LPE H161 H N N 530 
LPE H162 H N N 531 
LPE H171 H N N 532 
LPE H172 H N N 533 
LPE H181 H N N 534 
LPE H182 H N N 535 
LPE H191 H N N 536 
LPE H192 H N N 537 
LPE H201 H N N 538 
LPE H202 H N N 539 
LPE H211 H N N 540 
LPE H212 H N N 541 
LPE H221 H N N 542 
LPE H222 H N N 543 
LPE H231 H N N 544 
LPE H232 H N N 545 
LPE H241 H N N 546 
LPE H242 H N N 547 
LPE H251 H N N 548 
LPE H252 H N N 549 
LPE H261 H N N 550 
LPE H262 H N N 551 
LPE H271 H N N 552 
LPE H272 H N N 553 
LPE H281 H N N 554 
LPE H282 H N N 555 
LPE H283 H N N 556 
LYS N    N N N 557 
LYS CA   C N S 558 
LYS C    C N N 559 
LYS O    O N N 560 
LYS CB   C N N 561 
LYS CG   C N N 562 
LYS CD   C N N 563 
LYS CE   C N N 564 
LYS NZ   N N N 565 
LYS OXT  O N N 566 
LYS H    H N N 567 
LYS H2   H N N 568 
LYS HA   H N N 569 
LYS HB2  H N N 570 
LYS HB3  H N N 571 
LYS HG2  H N N 572 
LYS HG3  H N N 573 
LYS HD2  H N N 574 
LYS HD3  H N N 575 
LYS HE2  H N N 576 
LYS HE3  H N N 577 
LYS HZ1  H N N 578 
LYS HZ2  H N N 579 
LYS HZ3  H N N 580 
LYS HXT  H N N 581 
MET N    N N N 582 
MET CA   C N S 583 
MET C    C N N 584 
MET O    O N N 585 
MET CB   C N N 586 
MET CG   C N N 587 
MET SD   S N N 588 
MET CE   C N N 589 
MET OXT  O N N 590 
MET H    H N N 591 
MET H2   H N N 592 
MET HA   H N N 593 
MET HB2  H N N 594 
MET HB3  H N N 595 
MET HG2  H N N 596 
MET HG3  H N N 597 
MET HE1  H N N 598 
MET HE2  H N N 599 
MET HE3  H N N 600 
MET HXT  H N N 601 
PHE N    N N N 602 
PHE CA   C N S 603 
PHE C    C N N 604 
PHE O    O N N 605 
PHE CB   C N N 606 
PHE CG   C Y N 607 
PHE CD1  C Y N 608 
PHE CD2  C Y N 609 
PHE CE1  C Y N 610 
PHE CE2  C Y N 611 
PHE CZ   C Y N 612 
PHE OXT  O N N 613 
PHE H    H N N 614 
PHE H2   H N N 615 
PHE HA   H N N 616 
PHE HB2  H N N 617 
PHE HB3  H N N 618 
PHE HD1  H N N 619 
PHE HD2  H N N 620 
PHE HE1  H N N 621 
PHE HE2  H N N 622 
PHE HZ   H N N 623 
PHE HXT  H N N 624 
PLM C1   C N N 625 
PLM O1   O N N 626 
PLM O2   O N N 627 
PLM C2   C N N 628 
PLM C3   C N N 629 
PLM C4   C N N 630 
PLM C5   C N N 631 
PLM C6   C N N 632 
PLM C7   C N N 633 
PLM C8   C N N 634 
PLM C9   C N N 635 
PLM CA   C N N 636 
PLM CB   C N N 637 
PLM CC   C N N 638 
PLM CD   C N N 639 
PLM CE   C N N 640 
PLM CF   C N N 641 
PLM CG   C N N 642 
PLM H    H N N 643 
PLM H21  H N N 644 
PLM H22  H N N 645 
PLM H31  H N N 646 
PLM H32  H N N 647 
PLM H41  H N N 648 
PLM H42  H N N 649 
PLM H51  H N N 650 
PLM H52  H N N 651 
PLM H61  H N N 652 
PLM H62  H N N 653 
PLM H71  H N N 654 
PLM H72  H N N 655 
PLM H81  H N N 656 
PLM H82  H N N 657 
PLM H91  H N N 658 
PLM H92  H N N 659 
PLM HA1  H N N 660 
PLM HA2  H N N 661 
PLM HB1  H N N 662 
PLM HB2  H N N 663 
PLM HC1  H N N 664 
PLM HC2  H N N 665 
PLM HD1  H N N 666 
PLM HD2  H N N 667 
PLM HE1  H N N 668 
PLM HE2  H N N 669 
PLM HF1  H N N 670 
PLM HF2  H N N 671 
PLM HG1  H N N 672 
PLM HG2  H N N 673 
PLM HG3  H N N 674 
PRO N    N N N 675 
PRO CA   C N S 676 
PRO C    C N N 677 
PRO O    O N N 678 
PRO CB   C N N 679 
PRO CG   C N N 680 
PRO CD   C N N 681 
PRO OXT  O N N 682 
PRO H    H N N 683 
PRO HA   H N N 684 
PRO HB2  H N N 685 
PRO HB3  H N N 686 
PRO HG2  H N N 687 
PRO HG3  H N N 688 
PRO HD2  H N N 689 
PRO HD3  H N N 690 
PRO HXT  H N N 691 
SER N    N N N 692 
SER CA   C N S 693 
SER C    C N N 694 
SER O    O N N 695 
SER CB   C N N 696 
SER OG   O N N 697 
SER OXT  O N N 698 
SER H    H N N 699 
SER H2   H N N 700 
SER HA   H N N 701 
SER HB2  H N N 702 
SER HB3  H N N 703 
SER HG   H N N 704 
SER HXT  H N N 705 
THR N    N N N 706 
THR CA   C N S 707 
THR C    C N N 708 
THR O    O N N 709 
THR CB   C N R 710 
THR OG1  O N N 711 
THR CG2  C N N 712 
THR OXT  O N N 713 
THR H    H N N 714 
THR H2   H N N 715 
THR HA   H N N 716 
THR HB   H N N 717 
THR HG1  H N N 718 
THR HG21 H N N 719 
THR HG22 H N N 720 
THR HG23 H N N 721 
THR HXT  H N N 722 
TRP N    N N N 723 
TRP CA   C N S 724 
TRP C    C N N 725 
TRP O    O N N 726 
TRP CB   C N N 727 
TRP CG   C Y N 728 
TRP CD1  C Y N 729 
TRP CD2  C Y N 730 
TRP NE1  N Y N 731 
TRP CE2  C Y N 732 
TRP CE3  C Y N 733 
TRP CZ2  C Y N 734 
TRP CZ3  C Y N 735 
TRP CH2  C Y N 736 
TRP OXT  O N N 737 
TRP H    H N N 738 
TRP H2   H N N 739 
TRP HA   H N N 740 
TRP HB2  H N N 741 
TRP HB3  H N N 742 
TRP HD1  H N N 743 
TRP HE1  H N N 744 
TRP HE3  H N N 745 
TRP HZ2  H N N 746 
TRP HZ3  H N N 747 
TRP HH2  H N N 748 
TRP HXT  H N N 749 
TYR N    N N N 750 
TYR CA   C N S 751 
TYR C    C N N 752 
TYR O    O N N 753 
TYR CB   C N N 754 
TYR CG   C Y N 755 
TYR CD1  C Y N 756 
TYR CD2  C Y N 757 
TYR CE1  C Y N 758 
TYR CE2  C Y N 759 
TYR CZ   C Y N 760 
TYR OH   O N N 761 
TYR OXT  O N N 762 
TYR H    H N N 763 
TYR H2   H N N 764 
TYR HA   H N N 765 
TYR HB2  H N N 766 
TYR HB3  H N N 767 
TYR HD1  H N N 768 
TYR HD2  H N N 769 
TYR HE1  H N N 770 
TYR HE2  H N N 771 
TYR HH   H N N 772 
TYR HXT  H N N 773 
VAL N    N N N 774 
VAL CA   C N S 775 
VAL C    C N N 776 
VAL O    O N N 777 
VAL CB   C N N 778 
VAL CG1  C N N 779 
VAL CG2  C N N 780 
VAL OXT  O N N 781 
VAL H    H N N 782 
VAL H2   H N N 783 
VAL HA   H N N 784 
VAL HB   H N N 785 
VAL HG11 H N N 786 
VAL HG12 H N N 787 
VAL HG13 H N N 788 
VAL HG21 H N N 789 
VAL HG22 H N N 790 
VAL HG23 H N N 791 
VAL HXT  H N N 792 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
3PE P   O11  sing N N 1   
3PE P   O12  sing N N 2   
3PE P   O13  sing N N 3   
3PE P   O14  doub N N 4   
3PE N   C12  sing N N 5   
3PE N   HN1  sing N N 6   
3PE N   HN2  sing N N 7   
3PE O11 C1   sing N N 8   
3PE O13 C11  sing N N 9   
3PE C11 C12  sing N N 10  
3PE C11 H111 sing N N 11  
3PE C11 H112 sing N N 12  
3PE C12 H121 sing N N 13  
3PE C12 H122 sing N N 14  
3PE C1  C2   sing N N 15  
3PE C1  H11  sing N N 16  
3PE C1  H12  sing N N 17  
3PE C2  C3   sing N N 18  
3PE C2  O21  sing N N 19  
3PE C2  H2   sing N N 20  
3PE C3  O31  sing N N 21  
3PE C3  H31  sing N N 22  
3PE C3  H32  sing N N 23  
3PE O31 C31  sing N N 24  
3PE O32 C31  doub N N 25  
3PE C31 C32  sing N N 26  
3PE C32 C33  sing N N 27  
3PE C32 H321 sing N N 28  
3PE C32 H322 sing N N 29  
3PE C33 C34  sing N N 30  
3PE C33 H331 sing N N 31  
3PE C33 H332 sing N N 32  
3PE C34 C35  sing N N 33  
3PE C34 H341 sing N N 34  
3PE C34 H342 sing N N 35  
3PE C35 C36  sing N N 36  
3PE C35 H351 sing N N 37  
3PE C35 H352 sing N N 38  
3PE C36 C37  sing N N 39  
3PE C36 H361 sing N N 40  
3PE C36 H362 sing N N 41  
3PE C37 C38  sing N N 42  
3PE C37 H371 sing N N 43  
3PE C37 H372 sing N N 44  
3PE C38 C39  sing N N 45  
3PE C38 H381 sing N N 46  
3PE C38 H382 sing N N 47  
3PE C39 C3A  sing N N 48  
3PE C39 H391 sing N N 49  
3PE C39 H392 sing N N 50  
3PE C3A C3B  sing N N 51  
3PE C3A H3A1 sing N N 52  
3PE C3A H3A2 sing N N 53  
3PE C3B C3C  sing N N 54  
3PE C3B H3B1 sing N N 55  
3PE C3B H3B2 sing N N 56  
3PE C3C C3D  sing N N 57  
3PE C3C H3C1 sing N N 58  
3PE C3C H3C2 sing N N 59  
3PE C3D C3E  sing N N 60  
3PE C3D H3D1 sing N N 61  
3PE C3D H3D2 sing N N 62  
3PE C3E C3F  sing N N 63  
3PE C3E H3E1 sing N N 64  
3PE C3E H3E2 sing N N 65  
3PE C3F C3G  sing N N 66  
3PE C3F H3F1 sing N N 67  
3PE C3F H3F2 sing N N 68  
3PE C3G C3H  sing N N 69  
3PE C3G H3G1 sing N N 70  
3PE C3G H3G2 sing N N 71  
3PE C3H C3I  sing N N 72  
3PE C3H H3H1 sing N N 73  
3PE C3H H3H2 sing N N 74  
3PE C3I H3I1 sing N N 75  
3PE C3I H3I2 sing N N 76  
3PE C3I H3I3 sing N N 77  
3PE O21 C21  sing N N 78  
3PE O22 C21  doub N N 79  
3PE C21 C22  sing N N 80  
3PE C22 C23  sing N N 81  
3PE C22 H221 sing N N 82  
3PE C22 H222 sing N N 83  
3PE C23 C24  sing N N 84  
3PE C23 H231 sing N N 85  
3PE C23 H232 sing N N 86  
3PE C24 C25  sing N N 87  
3PE C24 H241 sing N N 88  
3PE C24 H242 sing N N 89  
3PE C25 C26  sing N N 90  
3PE C25 H251 sing N N 91  
3PE C25 H252 sing N N 92  
3PE C26 C27  sing N N 93  
3PE C26 H261 sing N N 94  
3PE C26 H262 sing N N 95  
3PE C27 C28  sing N N 96  
3PE C27 H271 sing N N 97  
3PE C27 H272 sing N N 98  
3PE C28 C29  sing N N 99  
3PE C28 H281 sing N N 100 
3PE C28 H282 sing N N 101 
3PE C29 C2A  sing N N 102 
3PE C29 H291 sing N N 103 
3PE C29 H292 sing N N 104 
3PE C2A C2B  sing N N 105 
3PE C2A H2A1 sing N N 106 
3PE C2A H2A2 sing N N 107 
3PE C2B C2C  sing N N 108 
3PE C2B H2B1 sing N N 109 
3PE C2B H2B2 sing N N 110 
3PE C2C C2D  sing N N 111 
3PE C2C H2C1 sing N N 112 
3PE C2C H2C2 sing N N 113 
3PE C2D C2E  sing N N 114 
3PE C2D H2D1 sing N N 115 
3PE C2D H2D2 sing N N 116 
3PE C2E C2F  sing N N 117 
3PE C2E H2E1 sing N N 118 
3PE C2E H2E2 sing N N 119 
3PE C2F C2G  sing N N 120 
3PE C2F H2F1 sing N N 121 
3PE C2F H2F2 sing N N 122 
3PE C2G C2H  sing N N 123 
3PE C2G H2G1 sing N N 124 
3PE C2G H2G2 sing N N 125 
3PE C2H C2I  sing N N 126 
3PE C2H H2H1 sing N N 127 
3PE C2H H2H2 sing N N 128 
3PE C2I H2I1 sing N N 129 
3PE C2I H2I2 sing N N 130 
3PE C2I H2I3 sing N N 131 
3PE O12 H1   sing N N 132 
ACD C1  C2   sing N N 133 
ACD C1  O1   doub N N 134 
ACD C1  O2   sing N N 135 
ACD C2  C3   sing N N 136 
ACD C2  H21  sing N N 137 
ACD C2  H22  sing N N 138 
ACD C3  C4   sing N N 139 
ACD C3  H31  sing N N 140 
ACD C3  H32  sing N N 141 
ACD C4  C5   sing N N 142 
ACD C4  H41  sing N N 143 
ACD C4  H42  sing N N 144 
ACD C5  C6   doub N Z 145 
ACD C5  H5   sing N N 146 
ACD C6  C7   sing N N 147 
ACD C6  H6   sing N N 148 
ACD C7  C8   sing N N 149 
ACD C7  H71  sing N N 150 
ACD C7  H72  sing N N 151 
ACD C8  C9   doub N Z 152 
ACD C8  H8   sing N N 153 
ACD C9  C10  sing N N 154 
ACD C9  H9   sing N N 155 
ACD C10 C11  sing N N 156 
ACD C10 H101 sing N N 157 
ACD C10 H102 sing N N 158 
ACD C11 C12  doub N Z 159 
ACD C11 H11  sing N N 160 
ACD C12 C13  sing N N 161 
ACD C12 H12  sing N N 162 
ACD C13 C14  sing N N 163 
ACD C13 H131 sing N N 164 
ACD C13 H132 sing N N 165 
ACD C14 C15  doub N Z 166 
ACD C14 H14  sing N N 167 
ACD C15 C16  sing N N 168 
ACD C15 H15  sing N N 169 
ACD C16 C17  sing N N 170 
ACD C16 H161 sing N N 171 
ACD C16 H162 sing N N 172 
ACD C17 C18  sing N N 173 
ACD C17 H171 sing N N 174 
ACD C17 H172 sing N N 175 
ACD C18 C19  sing N N 176 
ACD C18 H181 sing N N 177 
ACD C18 H182 sing N N 178 
ACD C19 C20  sing N N 179 
ACD C19 H191 sing N N 180 
ACD C19 H192 sing N N 181 
ACD C20 H201 sing N N 182 
ACD C20 H202 sing N N 183 
ACD C20 H203 sing N N 184 
ACD O2  HO2  sing N N 185 
ALA N   CA   sing N N 186 
ALA N   H    sing N N 187 
ALA N   H2   sing N N 188 
ALA CA  C    sing N N 189 
ALA CA  CB   sing N N 190 
ALA CA  HA   sing N N 191 
ALA C   O    doub N N 192 
ALA C   OXT  sing N N 193 
ALA CB  HB1  sing N N 194 
ALA CB  HB2  sing N N 195 
ALA CB  HB3  sing N N 196 
ALA OXT HXT  sing N N 197 
ARG N   CA   sing N N 198 
ARG N   H    sing N N 199 
ARG N   H2   sing N N 200 
ARG CA  C    sing N N 201 
ARG CA  CB   sing N N 202 
ARG CA  HA   sing N N 203 
ARG C   O    doub N N 204 
ARG C   OXT  sing N N 205 
ARG CB  CG   sing N N 206 
ARG CB  HB2  sing N N 207 
ARG CB  HB3  sing N N 208 
ARG CG  CD   sing N N 209 
ARG CG  HG2  sing N N 210 
ARG CG  HG3  sing N N 211 
ARG CD  NE   sing N N 212 
ARG CD  HD2  sing N N 213 
ARG CD  HD3  sing N N 214 
ARG NE  CZ   sing N N 215 
ARG NE  HE   sing N N 216 
ARG CZ  NH1  sing N N 217 
ARG CZ  NH2  doub N N 218 
ARG NH1 HH11 sing N N 219 
ARG NH1 HH12 sing N N 220 
ARG NH2 HH21 sing N N 221 
ARG NH2 HH22 sing N N 222 
ARG OXT HXT  sing N N 223 
ASN N   CA   sing N N 224 
ASN N   H    sing N N 225 
ASN N   H2   sing N N 226 
ASN CA  C    sing N N 227 
ASN CA  CB   sing N N 228 
ASN CA  HA   sing N N 229 
ASN C   O    doub N N 230 
ASN C   OXT  sing N N 231 
ASN CB  CG   sing N N 232 
ASN CB  HB2  sing N N 233 
ASN CB  HB3  sing N N 234 
ASN CG  OD1  doub N N 235 
ASN CG  ND2  sing N N 236 
ASN ND2 HD21 sing N N 237 
ASN ND2 HD22 sing N N 238 
ASN OXT HXT  sing N N 239 
ASP N   CA   sing N N 240 
ASP N   H    sing N N 241 
ASP N   H2   sing N N 242 
ASP CA  C    sing N N 243 
ASP CA  CB   sing N N 244 
ASP CA  HA   sing N N 245 
ASP C   O    doub N N 246 
ASP C   OXT  sing N N 247 
ASP CB  CG   sing N N 248 
ASP CB  HB2  sing N N 249 
ASP CB  HB3  sing N N 250 
ASP CG  OD1  doub N N 251 
ASP CG  OD2  sing N N 252 
ASP OD2 HD2  sing N N 253 
ASP OXT HXT  sing N N 254 
CLR C1  C2   sing N N 255 
CLR C1  C10  sing N N 256 
CLR C1  H11  sing N N 257 
CLR C1  H12  sing N N 258 
CLR C2  C3   sing N N 259 
CLR C2  H21  sing N N 260 
CLR C2  H22  sing N N 261 
CLR C3  C4   sing N N 262 
CLR C3  O1   sing N N 263 
CLR C3  H3   sing N N 264 
CLR C4  C5   sing N N 265 
CLR C4  H41  sing N N 266 
CLR C4  H42  sing N N 267 
CLR C5  C6   doub N N 268 
CLR C5  C10  sing N N 269 
CLR C6  C7   sing N N 270 
CLR C6  H6   sing N N 271 
CLR C7  C8   sing N N 272 
CLR C7  H71  sing N N 273 
CLR C7  H72  sing N N 274 
CLR C8  C9   sing N N 275 
CLR C8  C14  sing N N 276 
CLR C8  H8   sing N N 277 
CLR C9  C10  sing N N 278 
CLR C9  C11  sing N N 279 
CLR C9  H9   sing N N 280 
CLR C10 C19  sing N N 281 
CLR C11 C12  sing N N 282 
CLR C11 H111 sing N N 283 
CLR C11 H112 sing N N 284 
CLR C12 C13  sing N N 285 
CLR C12 H121 sing N N 286 
CLR C12 H122 sing N N 287 
CLR C13 C14  sing N N 288 
CLR C13 C17  sing N N 289 
CLR C13 C18  sing N N 290 
CLR C14 C15  sing N N 291 
CLR C14 H14  sing N N 292 
CLR C15 C16  sing N N 293 
CLR C15 H151 sing N N 294 
CLR C15 H152 sing N N 295 
CLR C16 C17  sing N N 296 
CLR C16 H161 sing N N 297 
CLR C16 H162 sing N N 298 
CLR C17 C20  sing N N 299 
CLR C17 H17  sing N N 300 
CLR C18 H181 sing N N 301 
CLR C18 H182 sing N N 302 
CLR C18 H183 sing N N 303 
CLR C19 H191 sing N N 304 
CLR C19 H192 sing N N 305 
CLR C19 H193 sing N N 306 
CLR C20 C21  sing N N 307 
CLR C20 C22  sing N N 308 
CLR C20 H20  sing N N 309 
CLR C21 H211 sing N N 310 
CLR C21 H212 sing N N 311 
CLR C21 H213 sing N N 312 
CLR C22 C23  sing N N 313 
CLR C22 H221 sing N N 314 
CLR C22 H222 sing N N 315 
CLR C23 C24  sing N N 316 
CLR C23 H231 sing N N 317 
CLR C23 H232 sing N N 318 
CLR C24 C25  sing N N 319 
CLR C24 H241 sing N N 320 
CLR C24 H242 sing N N 321 
CLR C25 C26  sing N N 322 
CLR C25 C27  sing N N 323 
CLR C25 H25  sing N N 324 
CLR C26 H261 sing N N 325 
CLR C26 H262 sing N N 326 
CLR C26 H263 sing N N 327 
CLR C27 H271 sing N N 328 
CLR C27 H272 sing N N 329 
CLR C27 H273 sing N N 330 
CLR O1  H1   sing N N 331 
CYS N   CA   sing N N 332 
CYS N   H    sing N N 333 
CYS N   H2   sing N N 334 
CYS CA  C    sing N N 335 
CYS CA  CB   sing N N 336 
CYS CA  HA   sing N N 337 
CYS C   O    doub N N 338 
CYS C   OXT  sing N N 339 
CYS CB  SG   sing N N 340 
CYS CB  HB2  sing N N 341 
CYS CB  HB3  sing N N 342 
CYS SG  HG   sing N N 343 
CYS OXT HXT  sing N N 344 
GLN N   CA   sing N N 345 
GLN N   H    sing N N 346 
GLN N   H2   sing N N 347 
GLN CA  C    sing N N 348 
GLN CA  CB   sing N N 349 
GLN CA  HA   sing N N 350 
GLN C   O    doub N N 351 
GLN C   OXT  sing N N 352 
GLN CB  CG   sing N N 353 
GLN CB  HB2  sing N N 354 
GLN CB  HB3  sing N N 355 
GLN CG  CD   sing N N 356 
GLN CG  HG2  sing N N 357 
GLN CG  HG3  sing N N 358 
GLN CD  OE1  doub N N 359 
GLN CD  NE2  sing N N 360 
GLN NE2 HE21 sing N N 361 
GLN NE2 HE22 sing N N 362 
GLN OXT HXT  sing N N 363 
GLU N   CA   sing N N 364 
GLU N   H    sing N N 365 
GLU N   H2   sing N N 366 
GLU CA  C    sing N N 367 
GLU CA  CB   sing N N 368 
GLU CA  HA   sing N N 369 
GLU C   O    doub N N 370 
GLU C   OXT  sing N N 371 
GLU CB  CG   sing N N 372 
GLU CB  HB2  sing N N 373 
GLU CB  HB3  sing N N 374 
GLU CG  CD   sing N N 375 
GLU CG  HG2  sing N N 376 
GLU CG  HG3  sing N N 377 
GLU CD  OE1  doub N N 378 
GLU CD  OE2  sing N N 379 
GLU OE2 HE2  sing N N 380 
GLU OXT HXT  sing N N 381 
GLY N   CA   sing N N 382 
GLY N   H    sing N N 383 
GLY N   H2   sing N N 384 
GLY CA  C    sing N N 385 
GLY CA  HA2  sing N N 386 
GLY CA  HA3  sing N N 387 
GLY C   O    doub N N 388 
GLY C   OXT  sing N N 389 
GLY OXT HXT  sing N N 390 
HIS N   CA   sing N N 391 
HIS N   H    sing N N 392 
HIS N   H2   sing N N 393 
HIS CA  C    sing N N 394 
HIS CA  CB   sing N N 395 
HIS CA  HA   sing N N 396 
HIS C   O    doub N N 397 
HIS C   OXT  sing N N 398 
HIS CB  CG   sing N N 399 
HIS CB  HB2  sing N N 400 
HIS CB  HB3  sing N N 401 
HIS CG  ND1  sing Y N 402 
HIS CG  CD2  doub Y N 403 
HIS ND1 CE1  doub Y N 404 
HIS ND1 HD1  sing N N 405 
HIS CD2 NE2  sing Y N 406 
HIS CD2 HD2  sing N N 407 
HIS CE1 NE2  sing Y N 408 
HIS CE1 HE1  sing N N 409 
HIS NE2 HE2  sing N N 410 
HIS OXT HXT  sing N N 411 
HOH O   H1   sing N N 412 
HOH O   H2   sing N N 413 
ILE N   CA   sing N N 414 
ILE N   H    sing N N 415 
ILE N   H2   sing N N 416 
ILE CA  C    sing N N 417 
ILE CA  CB   sing N N 418 
ILE CA  HA   sing N N 419 
ILE C   O    doub N N 420 
ILE C   OXT  sing N N 421 
ILE CB  CG1  sing N N 422 
ILE CB  CG2  sing N N 423 
ILE CB  HB   sing N N 424 
ILE CG1 CD1  sing N N 425 
ILE CG1 HG12 sing N N 426 
ILE CG1 HG13 sing N N 427 
ILE CG2 HG21 sing N N 428 
ILE CG2 HG22 sing N N 429 
ILE CG2 HG23 sing N N 430 
ILE CD1 HD11 sing N N 431 
ILE CD1 HD12 sing N N 432 
ILE CD1 HD13 sing N N 433 
ILE OXT HXT  sing N N 434 
LEU N   CA   sing N N 435 
LEU N   H    sing N N 436 
LEU N   H2   sing N N 437 
LEU CA  C    sing N N 438 
LEU CA  CB   sing N N 439 
LEU CA  HA   sing N N 440 
LEU C   O    doub N N 441 
LEU C   OXT  sing N N 442 
LEU CB  CG   sing N N 443 
LEU CB  HB2  sing N N 444 
LEU CB  HB3  sing N N 445 
LEU CG  CD1  sing N N 446 
LEU CG  CD2  sing N N 447 
LEU CG  HG   sing N N 448 
LEU CD1 HD11 sing N N 449 
LEU CD1 HD12 sing N N 450 
LEU CD1 HD13 sing N N 451 
LEU CD2 HD21 sing N N 452 
LEU CD2 HD22 sing N N 453 
LEU CD2 HD23 sing N N 454 
LEU OXT HXT  sing N N 455 
LPE C1  O1   sing N N 456 
LPE C1  C2   sing N N 457 
LPE C1  H11  sing N N 458 
LPE C1  H12  sing N N 459 
LPE O1  C11  sing N N 460 
LPE C2  O2H  sing N N 461 
LPE C2  C3   sing N N 462 
LPE C2  H21  sing N N 463 
LPE O2H HO21 sing N N 464 
LPE C3  O3   sing N N 465 
LPE C3  H31  sing N N 466 
LPE C3  H32  sing N N 467 
LPE C11 C12  sing N N 468 
LPE C11 H111 sing N N 469 
LPE C11 H112 sing N N 470 
LPE C12 C13  sing N N 471 
LPE C12 H121 sing N N 472 
LPE C12 H122 sing N N 473 
LPE O3  P    sing N N 474 
LPE P   O31  doub N N 475 
LPE P   O32  sing N N 476 
LPE P   O33  sing N N 477 
LPE O32 HO31 sing N N 478 
LPE O33 C31  sing N N 479 
LPE C31 C32  sing N N 480 
LPE C31 H311 sing N N 481 
LPE C31 H312 sing N N 482 
LPE C32 N    sing N N 483 
LPE C32 H321 sing N N 484 
LPE C32 H322 sing N N 485 
LPE N   C1N  sing N N 486 
LPE N   C2N  sing N N 487 
LPE N   C3N  sing N N 488 
LPE C1N H1N1 sing N N 489 
LPE C1N H1N2 sing N N 490 
LPE C1N H1N3 sing N N 491 
LPE C2N H2N1 sing N N 492 
LPE C2N H2N2 sing N N 493 
LPE C2N H2N3 sing N N 494 
LPE C3N H3N1 sing N N 495 
LPE C3N H3N2 sing N N 496 
LPE C3N H3N3 sing N N 497 
LPE C13 C14  sing N N 498 
LPE C13 H131 sing N N 499 
LPE C13 H132 sing N N 500 
LPE C14 C15  sing N N 501 
LPE C14 H141 sing N N 502 
LPE C14 H142 sing N N 503 
LPE C15 C16  sing N N 504 
LPE C15 H151 sing N N 505 
LPE C15 H152 sing N N 506 
LPE C16 C17  sing N N 507 
LPE C16 H161 sing N N 508 
LPE C16 H162 sing N N 509 
LPE C17 C18  sing N N 510 
LPE C17 H171 sing N N 511 
LPE C17 H172 sing N N 512 
LPE C18 C19  sing N N 513 
LPE C18 H181 sing N N 514 
LPE C18 H182 sing N N 515 
LPE C19 C20  sing N N 516 
LPE C19 H191 sing N N 517 
LPE C19 H192 sing N N 518 
LPE C20 C21  sing N N 519 
LPE C20 H201 sing N N 520 
LPE C20 H202 sing N N 521 
LPE C21 C22  sing N N 522 
LPE C21 H211 sing N N 523 
LPE C21 H212 sing N N 524 
LPE C22 C23  sing N N 525 
LPE C22 H221 sing N N 526 
LPE C22 H222 sing N N 527 
LPE C23 C24  sing N N 528 
LPE C23 H231 sing N N 529 
LPE C23 H232 sing N N 530 
LPE C24 C25  sing N N 531 
LPE C24 H241 sing N N 532 
LPE C24 H242 sing N N 533 
LPE C25 C26  sing N N 534 
LPE C25 H251 sing N N 535 
LPE C25 H252 sing N N 536 
LPE C26 C27  sing N N 537 
LPE C26 H261 sing N N 538 
LPE C26 H262 sing N N 539 
LPE C27 C28  sing N N 540 
LPE C27 H271 sing N N 541 
LPE C27 H272 sing N N 542 
LPE C28 H281 sing N N 543 
LPE C28 H282 sing N N 544 
LPE C28 H283 sing N N 545 
LYS N   CA   sing N N 546 
LYS N   H    sing N N 547 
LYS N   H2   sing N N 548 
LYS CA  C    sing N N 549 
LYS CA  CB   sing N N 550 
LYS CA  HA   sing N N 551 
LYS C   O    doub N N 552 
LYS C   OXT  sing N N 553 
LYS CB  CG   sing N N 554 
LYS CB  HB2  sing N N 555 
LYS CB  HB3  sing N N 556 
LYS CG  CD   sing N N 557 
LYS CG  HG2  sing N N 558 
LYS CG  HG3  sing N N 559 
LYS CD  CE   sing N N 560 
LYS CD  HD2  sing N N 561 
LYS CD  HD3  sing N N 562 
LYS CE  NZ   sing N N 563 
LYS CE  HE2  sing N N 564 
LYS CE  HE3  sing N N 565 
LYS NZ  HZ1  sing N N 566 
LYS NZ  HZ2  sing N N 567 
LYS NZ  HZ3  sing N N 568 
LYS OXT HXT  sing N N 569 
MET N   CA   sing N N 570 
MET N   H    sing N N 571 
MET N   H2   sing N N 572 
MET CA  C    sing N N 573 
MET CA  CB   sing N N 574 
MET CA  HA   sing N N 575 
MET C   O    doub N N 576 
MET C   OXT  sing N N 577 
MET CB  CG   sing N N 578 
MET CB  HB2  sing N N 579 
MET CB  HB3  sing N N 580 
MET CG  SD   sing N N 581 
MET CG  HG2  sing N N 582 
MET CG  HG3  sing N N 583 
MET SD  CE   sing N N 584 
MET CE  HE1  sing N N 585 
MET CE  HE2  sing N N 586 
MET CE  HE3  sing N N 587 
MET OXT HXT  sing N N 588 
PHE N   CA   sing N N 589 
PHE N   H    sing N N 590 
PHE N   H2   sing N N 591 
PHE CA  C    sing N N 592 
PHE CA  CB   sing N N 593 
PHE CA  HA   sing N N 594 
PHE C   O    doub N N 595 
PHE C   OXT  sing N N 596 
PHE CB  CG   sing N N 597 
PHE CB  HB2  sing N N 598 
PHE CB  HB3  sing N N 599 
PHE CG  CD1  doub Y N 600 
PHE CG  CD2  sing Y N 601 
PHE CD1 CE1  sing Y N 602 
PHE CD1 HD1  sing N N 603 
PHE CD2 CE2  doub Y N 604 
PHE CD2 HD2  sing N N 605 
PHE CE1 CZ   doub Y N 606 
PHE CE1 HE1  sing N N 607 
PHE CE2 CZ   sing Y N 608 
PHE CE2 HE2  sing N N 609 
PHE CZ  HZ   sing N N 610 
PHE OXT HXT  sing N N 611 
PLM C1  O1   sing N N 612 
PLM C1  O2   doub N N 613 
PLM C1  C2   sing N N 614 
PLM O1  H    sing N N 615 
PLM C2  C3   sing N N 616 
PLM C2  H21  sing N N 617 
PLM C2  H22  sing N N 618 
PLM C3  C4   sing N N 619 
PLM C3  H31  sing N N 620 
PLM C3  H32  sing N N 621 
PLM C4  C5   sing N N 622 
PLM C4  H41  sing N N 623 
PLM C4  H42  sing N N 624 
PLM C5  C6   sing N N 625 
PLM C5  H51  sing N N 626 
PLM C5  H52  sing N N 627 
PLM C6  C7   sing N N 628 
PLM C6  H61  sing N N 629 
PLM C6  H62  sing N N 630 
PLM C7  C8   sing N N 631 
PLM C7  H71  sing N N 632 
PLM C7  H72  sing N N 633 
PLM C8  C9   sing N N 634 
PLM C8  H81  sing N N 635 
PLM C8  H82  sing N N 636 
PLM C9  CA   sing N N 637 
PLM C9  H91  sing N N 638 
PLM C9  H92  sing N N 639 
PLM CA  CB   sing N N 640 
PLM CA  HA1  sing N N 641 
PLM CA  HA2  sing N N 642 
PLM CB  CC   sing N N 643 
PLM CB  HB1  sing N N 644 
PLM CB  HB2  sing N N 645 
PLM CC  CD   sing N N 646 
PLM CC  HC1  sing N N 647 
PLM CC  HC2  sing N N 648 
PLM CD  CE   sing N N 649 
PLM CD  HD1  sing N N 650 
PLM CD  HD2  sing N N 651 
PLM CE  CF   sing N N 652 
PLM CE  HE1  sing N N 653 
PLM CE  HE2  sing N N 654 
PLM CF  CG   sing N N 655 
PLM CF  HF1  sing N N 656 
PLM CF  HF2  sing N N 657 
PLM CG  HG1  sing N N 658 
PLM CG  HG2  sing N N 659 
PLM CG  HG3  sing N N 660 
PRO N   CA   sing N N 661 
PRO N   CD   sing N N 662 
PRO N   H    sing N N 663 
PRO CA  C    sing N N 664 
PRO CA  CB   sing N N 665 
PRO CA  HA   sing N N 666 
PRO C   O    doub N N 667 
PRO C   OXT  sing N N 668 
PRO CB  CG   sing N N 669 
PRO CB  HB2  sing N N 670 
PRO CB  HB3  sing N N 671 
PRO CG  CD   sing N N 672 
PRO CG  HG2  sing N N 673 
PRO CG  HG3  sing N N 674 
PRO CD  HD2  sing N N 675 
PRO CD  HD3  sing N N 676 
PRO OXT HXT  sing N N 677 
SER N   CA   sing N N 678 
SER N   H    sing N N 679 
SER N   H2   sing N N 680 
SER CA  C    sing N N 681 
SER CA  CB   sing N N 682 
SER CA  HA   sing N N 683 
SER C   O    doub N N 684 
SER C   OXT  sing N N 685 
SER CB  OG   sing N N 686 
SER CB  HB2  sing N N 687 
SER CB  HB3  sing N N 688 
SER OG  HG   sing N N 689 
SER OXT HXT  sing N N 690 
THR N   CA   sing N N 691 
THR N   H    sing N N 692 
THR N   H2   sing N N 693 
THR CA  C    sing N N 694 
THR CA  CB   sing N N 695 
THR CA  HA   sing N N 696 
THR C   O    doub N N 697 
THR C   OXT  sing N N 698 
THR CB  OG1  sing N N 699 
THR CB  CG2  sing N N 700 
THR CB  HB   sing N N 701 
THR OG1 HG1  sing N N 702 
THR CG2 HG21 sing N N 703 
THR CG2 HG22 sing N N 704 
THR CG2 HG23 sing N N 705 
THR OXT HXT  sing N N 706 
TRP N   CA   sing N N 707 
TRP N   H    sing N N 708 
TRP N   H2   sing N N 709 
TRP CA  C    sing N N 710 
TRP CA  CB   sing N N 711 
TRP CA  HA   sing N N 712 
TRP C   O    doub N N 713 
TRP C   OXT  sing N N 714 
TRP CB  CG   sing N N 715 
TRP CB  HB2  sing N N 716 
TRP CB  HB3  sing N N 717 
TRP CG  CD1  doub Y N 718 
TRP CG  CD2  sing Y N 719 
TRP CD1 NE1  sing Y N 720 
TRP CD1 HD1  sing N N 721 
TRP CD2 CE2  doub Y N 722 
TRP CD2 CE3  sing Y N 723 
TRP NE1 CE2  sing Y N 724 
TRP NE1 HE1  sing N N 725 
TRP CE2 CZ2  sing Y N 726 
TRP CE3 CZ3  doub Y N 727 
TRP CE3 HE3  sing N N 728 
TRP CZ2 CH2  doub Y N 729 
TRP CZ2 HZ2  sing N N 730 
TRP CZ3 CH2  sing Y N 731 
TRP CZ3 HZ3  sing N N 732 
TRP CH2 HH2  sing N N 733 
TRP OXT HXT  sing N N 734 
TYR N   CA   sing N N 735 
TYR N   H    sing N N 736 
TYR N   H2   sing N N 737 
TYR CA  C    sing N N 738 
TYR CA  CB   sing N N 739 
TYR CA  HA   sing N N 740 
TYR C   O    doub N N 741 
TYR C   OXT  sing N N 742 
TYR CB  CG   sing N N 743 
TYR CB  HB2  sing N N 744 
TYR CB  HB3  sing N N 745 
TYR CG  CD1  doub Y N 746 
TYR CG  CD2  sing Y N 747 
TYR CD1 CE1  sing Y N 748 
TYR CD1 HD1  sing N N 749 
TYR CD2 CE2  doub Y N 750 
TYR CD2 HD2  sing N N 751 
TYR CE1 CZ   doub Y N 752 
TYR CE1 HE1  sing N N 753 
TYR CE2 CZ   sing Y N 754 
TYR CE2 HE2  sing N N 755 
TYR CZ  OH   sing N N 756 
TYR OH  HH   sing N N 757 
TYR OXT HXT  sing N N 758 
VAL N   CA   sing N N 759 
VAL N   H    sing N N 760 
VAL N   H2   sing N N 761 
VAL CA  C    sing N N 762 
VAL CA  CB   sing N N 763 
VAL CA  HA   sing N N 764 
VAL C   O    doub N N 765 
VAL C   OXT  sing N N 766 
VAL CB  CG1  sing N N 767 
VAL CB  CG2  sing N N 768 
VAL CB  HB   sing N N 769 
VAL CG1 HG11 sing N N 770 
VAL CG1 HG12 sing N N 771 
VAL CG1 HG13 sing N N 772 
VAL CG2 HG21 sing N N 773 
VAL CG2 HG22 sing N N 774 
VAL CG2 HG23 sing N N 775 
VAL OXT HXT  sing N N 776 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-07-06 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9INE 
_em_admin.last_update        2025-04-02 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              'Cryo-EM structure of human XPR1 in closed state in the presence of KIDINS220-1-432' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9INE 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
N  
NA 
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ALA A  1 226 ? 180.935 198.391 212.495 1.00 77.68  ? 226 ALA B N   1 
ATOM   2    C CA  . ALA A  1 226 ? 182.032 198.315 211.537 1.00 81.69  ? 226 ALA B CA  1 
ATOM   3    C C   . ALA A  1 226 ? 182.606 196.904 211.477 1.00 83.73  ? 226 ALA B C   1 
ATOM   4    O O   . ALA A  1 226 ? 183.823 196.718 211.471 1.00 86.01  ? 226 ALA B O   1 
ATOM   5    C CB  . ALA A  1 226 ? 183.120 199.316 211.895 1.00 79.82  ? 226 ALA B CB  1 
ATOM   6    N N   . GLN A  1 227 ? 181.720 195.913 211.437 1.00 83.13  ? 227 GLN B N   1 
ATOM   7    C CA  . GLN A  1 227 ? 182.160 194.529 211.361 1.00 84.22  ? 227 GLN B CA  1 
ATOM   8    C C   . GLN A  1 227 ? 182.842 194.268 210.020 1.00 84.98  ? 227 GLN B C   1 
ATOM   9    O O   . GLN A  1 227 ? 182.377 194.748 208.981 1.00 83.68  ? 227 GLN B O   1 
ATOM   10   C CB  . GLN A  1 227 ? 180.975 193.580 211.540 1.00 84.18  ? 227 GLN B CB  1 
ATOM   11   C CG  . GLN A  1 227 ? 180.263 193.722 212.875 1.00 85.05  ? 227 GLN B CG  1 
ATOM   12   C CD  . GLN A  1 227 ? 179.114 192.744 213.030 1.00 84.53  ? 227 GLN B CD  1 
ATOM   13   O OE1 . GLN A  1 227 ? 178.683 192.117 212.062 1.00 83.43  ? 227 GLN B OE1 1 
ATOM   14   N NE2 . GLN A  1 227 ? 178.614 192.608 214.252 1.00 82.85  ? 227 GLN B NE2 1 
ATOM   15   N N   . PRO A  1 228 ? 183.945 193.521 210.009 1.00 84.98  ? 228 PRO B N   1 
ATOM   16   C CA  . PRO A  1 228 ? 184.638 193.254 208.745 1.00 82.13  ? 228 PRO B CA  1 
ATOM   17   C C   . PRO A  1 228 ? 183.786 192.421 207.802 1.00 82.39  ? 228 PRO B C   1 
ATOM   18   O O   . PRO A  1 228 ? 183.003 191.565 208.221 1.00 82.56  ? 228 PRO B O   1 
ATOM   19   C CB  . PRO A  1 228 ? 185.893 192.489 209.182 1.00 77.38  ? 228 PRO B CB  1 
ATOM   20   C CG  . PRO A  1 228 ? 185.515 191.867 210.484 1.00 80.11  ? 228 PRO B CG  1 
ATOM   21   C CD  . PRO A  1 228 ? 184.585 192.842 211.148 1.00 82.05  ? 228 PRO B CD  1 
ATOM   22   N N   . ALA A  1 229 ? 183.949 192.688 206.510 1.00 75.87  ? 229 ALA B N   1 
ATOM   23   C CA  . ALA A  1 229 ? 183.219 191.946 205.499 1.00 71.87  ? 229 ALA B CA  1 
ATOM   24   C C   . ALA A  1 229 ? 183.750 190.516 205.405 1.00 73.11  ? 229 ALA B C   1 
ATOM   25   O O   . ALA A  1 229 ? 184.933 190.268 205.653 1.00 71.73  ? 229 ALA B O   1 
ATOM   26   C CB  . ALA A  1 229 ? 183.335 192.635 204.144 1.00 70.12  ? 229 ALA B CB  1 
ATOM   27   N N   . PRO A  1 230 ? 182.892 189.556 205.059 1.00 71.98  ? 230 PRO B N   1 
ATOM   28   C CA  . PRO A  1 230 ? 183.355 188.170 204.933 1.00 71.11  ? 230 PRO B CA  1 
ATOM   29   C C   . PRO A  1 230 ? 184.385 188.031 203.823 1.00 67.24  ? 230 PRO B C   1 
ATOM   30   O O   . PRO A  1 230 ? 184.389 188.787 202.851 1.00 70.35  ? 230 PRO B O   1 
ATOM   31   C CB  . PRO A  1 230 ? 182.073 187.393 204.607 1.00 70.00  ? 230 PRO B CB  1 
ATOM   32   C CG  . PRO A  1 230 ? 180.958 188.277 205.067 1.00 65.59  ? 230 PRO B CG  1 
ATOM   33   C CD  . PRO A  1 230 ? 181.440 189.675 204.848 1.00 66.14  ? 230 PRO B CD  1 
ATOM   34   N N   . ALA A  1 231 ? 185.280 187.055 203.987 1.00 59.84  ? 231 ALA B N   1 
ATOM   35   C CA  . ALA A  1 231 ? 186.301 186.820 202.971 1.00 66.57  ? 231 ALA B CA  1 
ATOM   36   C C   . ALA A  1 231 ? 185.682 186.417 201.641 1.00 65.18  ? 231 ALA B C   1 
ATOM   37   O O   . ALA A  1 231 ? 186.258 186.686 200.579 1.00 63.95  ? 231 ALA B O   1 
ATOM   38   C CB  . ALA A  1 231 ? 187.283 185.751 203.447 1.00 59.98  ? 231 ALA B CB  1 
ATOM   39   N N   . TRP A  1 232 ? 184.511 185.779 201.673 1.00 59.96  ? 232 TRP B N   1 
ATOM   40   C CA  . TRP A  1 232 ? 183.859 185.385 200.431 1.00 55.40  ? 232 TRP B CA  1 
ATOM   41   C C   . TRP A  1 232 ? 183.447 186.599 199.611 1.00 65.01  ? 232 TRP B C   1 
ATOM   42   O O   . TRP A  1 232 ? 183.591 186.599 198.384 1.00 68.93  ? 232 TRP B O   1 
ATOM   43   C CB  . TRP A  1 232 ? 182.653 184.496 200.727 1.00 56.48  ? 232 TRP B CB  1 
ATOM   44   C CG  . TRP A  1 232 ? 182.965 183.040 200.612 1.00 62.60  ? 232 TRP B CG  1 
ATOM   45   C CD1 . TRP A  1 232 ? 182.977 182.123 201.620 1.00 63.28  ? 232 TRP B CD1 1 
ATOM   46   C CD2 . TRP A  1 232 ? 183.325 182.332 199.420 1.00 67.28  ? 232 TRP B CD2 1 
ATOM   47   N NE1 . TRP A  1 232 ? 183.317 180.886 201.130 1.00 64.36  ? 232 TRP B NE1 1 
ATOM   48   C CE2 . TRP A  1 232 ? 183.536 180.988 199.782 1.00 67.60  ? 232 TRP B CE2 1 
ATOM   49   C CE3 . TRP A  1 232 ? 183.487 182.703 198.083 1.00 63.29  ? 232 TRP B CE3 1 
ATOM   50   C CZ2 . TRP A  1 232 ? 183.898 180.015 198.854 1.00 61.36  ? 232 TRP B CZ2 1 
ATOM   51   C CZ3 . TRP A  1 232 ? 183.848 181.735 197.166 1.00 62.41  ? 232 TRP B CZ3 1 
ATOM   52   C CH2 . TRP A  1 232 ? 184.049 180.408 197.555 1.00 57.14  ? 232 TRP B CH2 1 
ATOM   53   N N   . THR A  1 233 ? 182.944 187.652 200.261 1.00 56.01  ? 233 THR B N   1 
ATOM   54   C CA  . THR A  1 233 ? 182.545 188.831 199.500 1.00 47.13  ? 233 THR B CA  1 
ATOM   55   C C   . THR A  1 233 ? 183.757 189.597 198.981 1.00 49.53  ? 233 THR B C   1 
ATOM   56   O O   . THR A  1 233 ? 183.683 190.210 197.911 1.00 58.28  ? 233 THR B O   1 
ATOM   57   C CB  . THR A  1 233 ? 181.635 189.737 200.336 1.00 47.94  ? 233 THR B CB  1 
ATOM   58   O OG1 . THR A  1 233 ? 180.855 190.561 199.462 1.00 54.81  ? 233 THR B OG1 1 
ATOM   59   C CG2 . THR A  1 233 ? 182.433 190.633 201.261 1.00 47.25  ? 233 THR B CG2 1 
ATOM   60   N N   . THR A  1 234 ? 184.882 189.557 199.702 1.00 45.07  ? 234 THR B N   1 
ATOM   61   C CA  . THR A  1 234 ? 186.110 190.138 199.170 1.00 41.14  ? 234 THR B CA  1 
ATOM   62   C C   . THR A  1 234 ? 186.584 189.371 197.944 1.00 47.21  ? 234 THR B C   1 
ATOM   63   O O   . THR A  1 234 ? 187.006 189.972 196.947 1.00 45.53  ? 234 THR B O   1 
ATOM   64   C CB  . THR A  1 234 ? 187.196 190.161 200.241 1.00 34.66  ? 234 THR B CB  1 
ATOM   65   O OG1 . THR A  1 234 ? 186.629 190.568 201.490 1.00 45.16  ? 234 THR B OG1 1 
ATOM   66   C CG2 . THR A  1 234 ? 188.286 191.137 199.854 1.00 32.15  ? 234 THR B CG2 1 
ATOM   67   N N   . PHE A  1 235 ? 186.507 188.040 197.991 1.00 62.74  ? 235 PHE B N   1 
ATOM   68   C CA  . PHE A  1 235 ? 186.831 187.255 196.807 1.00 60.09  ? 235 PHE B CA  1 
ATOM   69   C C   . PHE A  1 235 ? 185.887 187.585 195.660 1.00 55.89  ? 235 PHE B C   1 
ATOM   70   O O   . PHE A  1 235 ? 186.308 187.660 194.503 1.00 56.27  ? 235 PHE B O   1 
ATOM   71   C CB  . PHE A  1 235 ? 186.778 185.762 197.125 1.00 45.40  ? 235 PHE B CB  1 
ATOM   72   C CG  . PHE A  1 235 ? 186.633 184.896 195.909 1.00 45.30  ? 235 PHE B CG  1 
ATOM   73   C CD1 . PHE A  1 235 ? 187.717 184.651 195.089 1.00 45.97  ? 235 PHE B CD1 1 
ATOM   74   C CD2 . PHE A  1 235 ? 185.410 184.339 195.580 1.00 54.64  ? 235 PHE B CD2 1 
ATOM   75   C CE1 . PHE A  1 235 ? 187.587 183.863 193.966 1.00 54.63  ? 235 PHE B CE1 1 
ATOM   76   C CE2 . PHE A  1 235 ? 185.275 183.550 194.458 1.00 53.95  ? 235 PHE B CE2 1 
ATOM   77   C CZ  . PHE A  1 235 ? 186.365 183.311 193.650 1.00 53.64  ? 235 PHE B CZ  1 
ATOM   78   N N   . ARG A  1 236 ? 184.601 187.774 195.962 1.00 50.32  ? 236 ARG B N   1 
ATOM   79   C CA  . ARG A  1 236 ? 183.628 188.074 194.915 1.00 44.40  ? 236 ARG B CA  1 
ATOM   80   C C   . ARG A  1 236 ? 183.903 189.423 194.264 1.00 49.29  ? 236 ARG B C   1 
ATOM   81   O O   . ARG A  1 236 ? 183.833 189.548 193.036 1.00 59.53  ? 236 ARG B O   1 
ATOM   82   C CB  . ARG A  1 236 ? 182.212 188.033 195.485 1.00 48.86  ? 236 ARG B CB  1 
ATOM   83   C CG  . ARG A  1 236 ? 181.407 186.828 195.043 1.00 48.84  ? 236 ARG B CG  1 
ATOM   84   C CD  . ARG A  1 236 ? 179.938 186.993 195.375 1.00 51.73  ? 236 ARG B CD  1 
ATOM   85   N NE  . ARG A  1 236 ? 179.595 186.365 196.644 1.00 54.43  ? 236 ARG B NE  1 
ATOM   86   C CZ  . ARG A  1 236 ? 179.505 187.012 197.797 1.00 54.33  ? 236 ARG B CZ  1 
ATOM   87   N NH1 . ARG A  1 236 ? 179.714 188.315 197.875 1.00 56.71  ? 236 ARG B NH1 1 
ATOM   88   N NH2 . ARG A  1 236 ? 179.194 186.335 198.898 1.00 53.71  ? 236 ARG B NH2 1 
ATOM   89   N N   . VAL A  1 237 ? 184.210 190.448 195.064 1.00 54.39  ? 237 VAL B N   1 
ATOM   90   C CA  . VAL A  1 237 ? 184.493 191.754 194.476 1.00 56.25  ? 237 VAL B CA  1 
ATOM   91   C C   . VAL A  1 237 ? 185.792 191.706 193.683 1.00 58.90  ? 237 VAL B C   1 
ATOM   92   O O   . VAL A  1 237 ? 185.901 192.324 192.618 1.00 57.41  ? 237 VAL B O   1 
ATOM   93   C CB  . VAL A  1 237 ? 184.514 192.866 195.543 1.00 42.18  ? 237 VAL B CB  1 
ATOM   94   C CG1 . VAL A  1 237 ? 185.460 192.541 196.654 1.00 52.95  ? 237 VAL B CG1 1 
ATOM   95   C CG2 . VAL A  1 237 ? 184.911 194.182 194.912 1.00 41.92  ? 237 VAL B CG2 1 
ATOM   96   N N   . GLY A  1 238 ? 186.789 190.958 194.166 1.00 48.81  ? 238 GLY B N   1 
ATOM   97   C CA  . GLY A  1 238 ? 187.995 190.776 193.374 1.00 45.13  ? 238 GLY B CA  1 
ATOM   98   C C   . GLY A  1 238 ? 187.719 190.094 192.048 1.00 44.53  ? 238 GLY B C   1 
ATOM   99   O O   . GLY A  1 238 ? 188.219 190.518 191.003 1.00 51.19  ? 238 GLY B O   1 
ATOM   100  N N   . LEU A  1 239 ? 186.909 189.035 192.073 1.00 41.56  ? 239 LEU B N   1 
ATOM   101  C CA  . LEU A  1 239 ? 186.554 188.321 190.853 1.00 47.57  ? 239 LEU B CA  1 
ATOM   102  C C   . LEU A  1 239 ? 185.852 189.242 189.866 1.00 48.77  ? 239 LEU B C   1 
ATOM   103  O O   . LEU A  1 239 ? 186.194 189.279 188.678 1.00 53.27  ? 239 LEU B O   1 
ATOM   104  C CB  . LEU A  1 239 ? 185.665 187.126 191.204 1.00 51.35  ? 239 LEU B CB  1 
ATOM   105  C CG  . LEU A  1 239 ? 184.769 186.525 190.123 1.00 47.53  ? 239 LEU B CG  1 
ATOM   106  C CD1 . LEU A  1 239 ? 185.547 185.565 189.252 1.00 48.61  ? 239 LEU B CD1 1 
ATOM   107  C CD2 . LEU A  1 239 ? 183.577 185.829 190.750 1.00 49.86  ? 239 LEU B CD2 1 
ATOM   108  N N   . PHE A  1 240 ? 184.871 190.004 190.350 1.00 50.87  ? 240 PHE B N   1 
ATOM   109  C CA  . PHE A  1 240 ? 184.119 190.888 189.469 1.00 46.47  ? 240 PHE B CA  1 
ATOM   110  C C   . PHE A  1 240 ? 184.997 192.004 188.923 1.00 48.21  ? 240 PHE B C   1 
ATOM   111  O O   . PHE A  1 240 ? 184.883 192.367 187.749 1.00 54.63  ? 240 PHE B O   1 
ATOM   112  C CB  . PHE A  1 240 ? 182.910 191.453 190.207 1.00 43.68  ? 240 PHE B CB  1 
ATOM   113  C CG  . PHE A  1 240 ? 181.803 190.461 190.386 1.00 49.11  ? 240 PHE B CG  1 
ATOM   114  C CD1 . PHE A  1 240 ? 181.408 189.653 189.336 1.00 48.43  ? 240 PHE B CD1 1 
ATOM   115  C CD2 . PHE A  1 240 ? 181.160 190.331 191.602 1.00 50.57  ? 240 PHE B CD2 1 
ATOM   116  C CE1 . PHE A  1 240 ? 180.393 188.737 189.495 1.00 45.95  ? 240 PHE B CE1 1 
ATOM   117  C CE2 . PHE A  1 240 ? 180.144 189.416 191.766 1.00 50.73  ? 240 PHE B CE2 1 
ATOM   118  C CZ  . PHE A  1 240 ? 179.760 188.619 190.711 1.00 46.66  ? 240 PHE B CZ  1 
ATOM   119  N N   . CYS A  1 241 ? 185.892 192.550 189.749 1.00 44.39  ? 241 CYS B N   1 
ATOM   120  C CA  . CYS A  1 241 ? 186.780 193.606 189.278 1.00 46.73  ? 241 CYS B CA  1 
ATOM   121  C C   . CYS A  1 241 ? 187.757 193.084 188.232 1.00 50.90  ? 241 CYS B C   1 
ATOM   122  O O   . CYS A  1 241 ? 188.042 193.773 187.247 1.00 50.99  ? 241 CYS B O   1 
ATOM   123  C CB  . CYS A  1 241 ? 187.527 194.221 190.458 1.00 55.47  ? 241 CYS B CB  1 
ATOM   124  S SG  . CYS A  1 241 ? 186.602 195.527 191.293 1.00 82.99  ? 241 CYS B SG  1 
ATOM   125  N N   . GLY A  1 242 ? 188.280 191.872 188.423 1.00 49.38  ? 242 GLY B N   1 
ATOM   126  C CA  . GLY A  1 242 ? 189.164 191.299 187.421 1.00 43.45  ? 242 GLY B CA  1 
ATOM   127  C C   . GLY A  1 242 ? 188.454 191.008 186.113 1.00 45.71  ? 242 GLY B C   1 
ATOM   128  O O   . GLY A  1 242 ? 188.980 191.292 185.030 1.00 49.42  ? 242 GLY B O   1 
ATOM   129  N N   . ILE A  1 243 ? 187.251 190.433 186.194 1.00 43.35  ? 243 ILE B N   1 
ATOM   130  C CA  . ILE A  1 243 ? 186.463 190.200 184.990 1.00 44.98  ? 243 ILE B CA  1 
ATOM   131  C C   . ILE A  1 243 ? 186.169 191.521 184.293 1.00 53.37  ? 243 ILE B C   1 
ATOM   132  O O   . ILE A  1 243 ? 186.218 191.616 183.063 1.00 52.97  ? 243 ILE B O   1 
ATOM   133  C CB  . ILE A  1 243 ? 185.171 189.434 185.334 1.00 43.15  ? 243 ILE B CB  1 
ATOM   134  C CG1 . ILE A  1 243 ? 185.501 188.055 185.903 1.00 44.68  ? 243 ILE B CG1 1 
ATOM   135  C CG2 . ILE A  1 243 ? 184.294 189.281 184.107 1.00 52.51  ? 243 ILE B CG2 1 
ATOM   136  C CD1 . ILE A  1 243 ? 184.290 187.174 186.107 1.00 44.94  ? 243 ILE B CD1 1 
ATOM   137  N N   . PHE A  1 244 ? 185.886 192.568 185.072 1.00 54.29  ? 244 PHE B N   1 
ATOM   138  C CA  . PHE A  1 244 ? 185.629 193.884 184.500 1.00 47.81  ? 244 PHE B CA  1 
ATOM   139  C C   . PHE A  1 244 ? 186.861 194.434 183.798 1.00 51.80  ? 244 PHE B C   1 
ATOM   140  O O   . PHE A  1 244 ? 186.756 195.000 182.708 1.00 58.76  ? 244 PHE B O   1 
ATOM   141  C CB  . PHE A  1 244 ? 185.162 194.840 185.596 1.00 50.26  ? 244 PHE B CB  1 
ATOM   142  C CG  . PHE A  1 244 ? 184.706 196.173 185.084 1.00 47.82  ? 244 PHE B CG  1 
ATOM   143  C CD1 . PHE A  1 244 ? 183.550 196.282 184.333 1.00 45.52  ? 244 PHE B CD1 1 
ATOM   144  C CD2 . PHE A  1 244 ? 185.429 197.318 185.360 1.00 47.86  ? 244 PHE B CD2 1 
ATOM   145  C CE1 . PHE A  1 244 ? 183.129 197.506 183.863 1.00 48.88  ? 244 PHE B CE1 1 
ATOM   146  C CE2 . PHE A  1 244 ? 185.012 198.543 184.892 1.00 52.94  ? 244 PHE B CE2 1 
ATOM   147  C CZ  . PHE A  1 244 ? 183.860 198.637 184.142 1.00 53.23  ? 244 PHE B CZ  1 
ATOM   148  N N   . ILE A  1 245 ? 188.037 194.276 184.407 1.00 48.46  ? 245 ILE B N   1 
ATOM   149  C CA  . ILE A  1 245 ? 189.265 194.783 183.798 1.00 46.79  ? 245 ILE B CA  1 
ATOM   150  C C   . ILE A  1 245 ? 189.529 194.083 182.471 1.00 47.81  ? 245 ILE B C   1 
ATOM   151  O O   . ILE A  1 245 ? 189.815 194.726 181.451 1.00 54.18  ? 245 ILE B O   1 
ATOM   152  C CB  . ILE A  1 245 ? 190.450 194.618 184.766 1.00 41.57  ? 245 ILE B CB  1 
ATOM   153  C CG1 . ILE A  1 245 ? 190.353 195.628 185.908 1.00 41.78  ? 245 ILE B CG1 1 
ATOM   154  C CG2 . ILE A  1 245 ? 191.767 194.775 184.028 1.00 44.94  ? 245 ILE B CG2 1 
ATOM   155  C CD1 . ILE A  1 245 ? 191.473 195.512 186.912 1.00 43.43  ? 245 ILE B CD1 1 
ATOM   156  N N   . VAL A  1 246 ? 189.429 192.751 182.461 1.00 44.63  ? 246 VAL B N   1 
ATOM   157  C CA  . VAL A  1 246 ? 189.714 192.020 181.229 1.00 49.49  ? 246 VAL B CA  1 
ATOM   158  C C   . VAL A  1 246 ? 188.669 192.328 180.166 1.00 52.62  ? 246 VAL B C   1 
ATOM   159  O O   . VAL A  1 246 ? 188.998 192.494 178.985 1.00 55.85  ? 246 VAL B O   1 
ATOM   160  C CB  . VAL A  1 246 ? 189.819 190.510 181.498 1.00 40.96  ? 246 VAL B CB  1 
ATOM   161  C CG1 . VAL A  1 246 ? 190.329 189.801 180.259 1.00 34.87  ? 246 VAL B CG1 1 
ATOM   162  C CG2 . VAL A  1 246 ? 190.747 190.258 182.649 1.00 48.52  ? 246 VAL B CG2 1 
ATOM   163  N N   . LEU A  1 247 ? 187.395 192.410 180.558 1.00 48.82  ? 247 LEU B N   1 
ATOM   164  C CA  . LEU A  1 247 ? 186.348 192.727 179.596 1.00 44.48  ? 247 LEU B CA  1 
ATOM   165  C C   . LEU A  1 247 ? 186.522 194.134 179.041 1.00 57.65  ? 247 LEU B C   1 
ATOM   166  O O   . LEU A  1 247 ? 186.266 194.373 177.859 1.00 64.99  ? 247 LEU B O   1 
ATOM   167  C CB  . LEU A  1 247 ? 184.974 192.563 180.243 1.00 42.29  ? 247 LEU B CB  1 
ATOM   168  C CG  . LEU A  1 247 ? 184.436 191.134 180.299 1.00 38.72  ? 247 LEU B CG  1 
ATOM   169  C CD1 . LEU A  1 247 ? 183.171 191.067 181.127 1.00 48.94  ? 247 LEU B CD1 1 
ATOM   170  C CD2 . LEU A  1 247 ? 184.181 190.612 178.904 1.00 42.76  ? 247 LEU B CD2 1 
ATOM   171  N N   . ASN A  1 248 ? 186.963 195.077 179.875 1.00 58.47  ? 248 ASN B N   1 
ATOM   172  C CA  . ASN A  1 248 ? 187.206 196.436 179.404 1.00 49.99  ? 248 ASN B CA  1 
ATOM   173  C C   . ASN A  1 248 ? 188.362 196.482 178.415 1.00 57.87  ? 248 ASN B C   1 
ATOM   174  O O   . ASN A  1 248 ? 188.287 197.186 177.400 1.00 62.61  ? 248 ASN B O   1 
ATOM   175  C CB  . ASN A  1 248 ? 187.482 197.357 180.590 1.00 44.69  ? 248 ASN B CB  1 
ATOM   176  C CG  . ASN A  1 248 ? 186.300 198.232 180.928 1.00 52.85  ? 248 ASN B CG  1 
ATOM   177  O OD1 . ASN A  1 248 ? 185.267 198.180 180.264 1.00 59.53  ? 248 ASN B OD1 1 
ATOM   178  N ND2 . ASN A  1 248 ? 186.442 199.043 181.968 1.00 59.21  ? 248 ASN B ND2 1 
ATOM   179  N N   . ILE A  1 249 ? 189.443 195.750 178.694 1.00 54.84  ? 249 ILE B N   1 
ATOM   180  C CA  . ILE A  1 249 ? 190.561 195.716 177.753 1.00 56.87  ? 249 ILE B CA  1 
ATOM   181  C C   . ILE A  1 249 ? 190.129 195.075 176.440 1.00 56.76  ? 249 ILE B C   1 
ATOM   182  O O   . ILE A  1 249 ? 190.473 195.557 175.351 1.00 58.12  ? 249 ILE B O   1 
ATOM   183  C CB  . ILE A  1 249 ? 191.769 194.993 178.373 1.00 51.31  ? 249 ILE B CB  1 
ATOM   184  C CG1 . ILE A  1 249 ? 192.243 195.735 179.623 1.00 50.26  ? 249 ILE B CG1 1 
ATOM   185  C CG2 . ILE A  1 249 ? 192.897 194.888 177.362 1.00 48.71  ? 249 ILE B CG2 1 
ATOM   186  C CD1 . ILE A  1 249 ? 193.541 195.213 180.194 1.00 54.47  ? 249 ILE B CD1 1 
ATOM   187  N N   . THR A  1 250 ? 189.359 193.987 176.521 1.00 52.89  ? 250 THR B N   1 
ATOM   188  C CA  . THR A  1 250 ? 188.844 193.349 175.314 1.00 54.26  ? 250 THR B CA  1 
ATOM   189  C C   . THR A  1 250 ? 187.935 194.292 174.539 1.00 54.47  ? 250 THR B C   1 
ATOM   190  O O   . THR A  1 250 ? 187.969 194.325 173.306 1.00 56.16  ? 250 THR B O   1 
ATOM   191  C CB  . THR A  1 250 ? 188.089 192.070 175.675 1.00 55.39  ? 250 THR B CB  1 
ATOM   192  O OG1 . THR A  1 250 ? 188.857 191.307 176.613 1.00 70.81  ? 250 THR B OG1 1 
ATOM   193  C CG2 . THR A  1 250 ? 187.845 191.233 174.433 1.00 61.60  ? 250 THR B CG2 1 
ATOM   194  N N   . LEU A  1 251 ? 187.113 195.065 175.250 1.00 55.15  ? 251 LEU B N   1 
ATOM   195  C CA  . LEU A  1 251 ? 186.206 196.008 174.608 1.00 56.69  ? 251 LEU B CA  1 
ATOM   196  C C   . LEU A  1 251 ? 186.973 197.113 173.897 1.00 57.68  ? 251 LEU B C   1 
ATOM   197  O O   . LEU A  1 251 ? 186.640 197.478 172.764 1.00 65.54  ? 251 LEU B O   1 
ATOM   198  C CB  . LEU A  1 251 ? 185.264 196.588 175.661 1.00 51.21  ? 251 LEU B CB  1 
ATOM   199  C CG  . LEU A  1 251 ? 183.913 197.188 175.286 1.00 45.16  ? 251 LEU B CG  1 
ATOM   200  C CD1 . LEU A  1 251 ? 183.071 197.257 176.539 1.00 50.51  ? 251 LEU B CD1 1 
ATOM   201  C CD2 . LEU A  1 251 ? 184.066 198.570 174.682 1.00 53.28  ? 251 LEU B CD2 1 
ATOM   202  N N   . VAL A  1 252 ? 188.004 197.656 174.547 1.00 46.28  ? 252 VAL B N   1 
ATOM   203  C CA  . VAL A  1 252 ? 188.823 198.688 173.918 1.00 42.99  ? 252 VAL B CA  1 
ATOM   204  C C   . VAL A  1 252 ? 189.510 198.138 172.675 1.00 51.81  ? 252 VAL B C   1 
ATOM   205  O O   . VAL A  1 252 ? 189.540 198.788 171.621 1.00 46.01  ? 252 VAL B O   1 
ATOM   206  C CB  . VAL A  1 252 ? 189.842 199.247 174.929 1.00 41.01  ? 252 VAL B CB  1 
ATOM   207  C CG1 . VAL A  1 252 ? 190.883 200.095 174.223 1.00 43.89  ? 252 VAL B CG1 1 
ATOM   208  C CG2 . VAL A  1 252 ? 189.134 200.051 176.005 1.00 46.71  ? 252 VAL B CG2 1 
ATOM   209  N N   . LEU A  1 253 ? 190.066 196.927 172.777 1.00 67.23  ? 253 LEU B N   1 
ATOM   210  C CA  . LEU A  1 253 ? 190.756 196.333 171.637 1.00 63.51  ? 253 LEU B CA  1 
ATOM   211  C C   . LEU A  1 253 ? 189.791 196.037 170.496 1.00 59.17  ? 253 LEU B C   1 
ATOM   212  O O   . LEU A  1 253 ? 190.134 196.219 169.324 1.00 55.31  ? 253 LEU B O   1 
ATOM   213  C CB  . LEU A  1 253 ? 191.489 195.065 172.070 1.00 52.30  ? 253 LEU B CB  1 
ATOM   214  C CG  . LEU A  1 253 ? 192.994 195.225 172.280 1.00 54.52  ? 253 LEU B CG  1 
ATOM   215  C CD1 . LEU A  1 253 ? 193.285 196.303 173.307 1.00 56.08  ? 253 LEU B CD1 1 
ATOM   216  C CD2 . LEU A  1 253 ? 193.601 193.909 172.714 1.00 65.55  ? 253 LEU B CD2 1 
ATOM   217  N N   . ALA A  1 254 ? 188.583 195.570 170.816 1.00 59.93  ? 254 ALA B N   1 
ATOM   218  C CA  . ALA A  1 254 ? 187.585 195.327 169.781 1.00 63.88  ? 254 ALA B CA  1 
ATOM   219  C C   . ALA A  1 254 ? 187.157 196.626 169.113 1.00 66.67  ? 254 ALA B C   1 
ATOM   220  O O   . ALA A  1 254 ? 186.986 196.673 167.889 1.00 72.42  ? 254 ALA B O   1 
ATOM   221  C CB  . ALA A  1 254 ? 186.378 194.604 170.375 1.00 63.15  ? 254 ALA B CB  1 
ATOM   222  N N   . ALA A  1 255 ? 186.975 197.688 169.900 1.00 66.01  ? 255 ALA B N   1 
ATOM   223  C CA  . ALA A  1 255 ? 186.589 198.973 169.331 1.00 66.69  ? 255 ALA B CA  1 
ATOM   224  C C   . ALA A  1 255 ? 187.667 199.514 168.402 1.00 71.23  ? 255 ALA B C   1 
ATOM   225  O O   . ALA A  1 255 ? 187.362 200.024 167.318 1.00 75.09  ? 255 ALA B O   1 
ATOM   226  C CB  . ALA A  1 255 ? 186.295 199.974 170.448 1.00 62.07  ? 255 ALA B CB  1 
ATOM   227  N N   . VAL A  1 256 ? 188.933 199.409 168.805 1.00 67.20  ? 256 VAL B N   1 
ATOM   228  C CA  . VAL A  1 256 ? 189.990 199.999 167.991 1.00 65.87  ? 256 VAL B CA  1 
ATOM   229  C C   . VAL A  1 256 ? 190.342 199.112 166.797 1.00 67.93  ? 256 VAL B C   1 
ATOM   230  O O   . VAL A  1 256 ? 190.739 199.621 165.742 1.00 71.53  ? 256 VAL B O   1 
ATOM   231  C CB  . VAL A  1 256 ? 191.223 200.310 168.859 1.00 64.52  ? 256 VAL B CB  1 
ATOM   232  C CG1 . VAL A  1 256 ? 191.861 199.037 169.374 1.00 67.27  ? 256 VAL B CG1 1 
ATOM   233  C CG2 . VAL A  1 256 ? 192.232 201.142 168.080 1.00 63.58  ? 256 VAL B CG2 1 
ATOM   234  N N   . PHE A  1 257 ? 190.198 197.791 166.921 1.00 72.94  ? 257 PHE B N   1 
ATOM   235  C CA  . PHE A  1 257 ? 190.564 196.864 165.854 1.00 74.54  ? 257 PHE B CA  1 
ATOM   236  C C   . PHE A  1 257 ? 189.372 196.466 164.989 1.00 77.41  ? 257 PHE B C   1 
ATOM   237  O O   . PHE A  1 257 ? 189.368 196.712 163.780 1.00 76.44  ? 257 PHE B O   1 
ATOM   238  C CB  . PHE A  1 257 ? 191.219 195.609 166.447 1.00 72.54  ? 257 PHE B CB  1 
ATOM   239  C CG  . PHE A  1 257 ? 192.697 195.740 166.664 1.00 76.63  ? 257 PHE B CG  1 
ATOM   240  C CD1 . PHE A  1 257 ? 193.589 195.400 165.664 1.00 76.02  ? 257 PHE B CD1 1 
ATOM   241  C CD2 . PHE A  1 257 ? 193.195 196.191 167.873 1.00 77.01  ? 257 PHE B CD2 1 
ATOM   242  C CE1 . PHE A  1 257 ? 194.950 195.516 165.863 1.00 76.06  ? 257 PHE B CE1 1 
ATOM   243  C CE2 . PHE A  1 257 ? 194.554 196.310 168.078 1.00 75.37  ? 257 PHE B CE2 1 
ATOM   244  C CZ  . PHE A  1 257 ? 195.433 195.972 167.072 1.00 75.36  ? 257 PHE B CZ  1 
ATOM   245  N N   . LYS A  1 258 ? 188.354 195.855 165.591 1.00 80.90  ? 258 LYS B N   1 
ATOM   246  C CA  . LYS A  1 258 ? 187.243 195.260 164.849 1.00 77.75  ? 258 LYS B CA  1 
ATOM   247  C C   . LYS A  1 258 ? 186.079 196.244 164.840 1.00 82.37  ? 258 LYS B C   1 
ATOM   248  O O   . LYS A  1 258 ? 185.262 196.266 165.763 1.00 81.68  ? 258 LYS B O   1 
ATOM   249  C CB  . LYS A  1 258 ? 186.838 193.924 165.462 1.00 75.57  ? 258 LYS B CB  1 
ATOM   250  C CG  . LYS A  1 258 ? 185.871 193.116 164.609 1.00 80.46  ? 258 LYS B CG  1 
ATOM   251  C CD  . LYS A  1 258 ? 184.435 193.264 165.084 1.00 80.87  ? 258 LYS B CD  1 
ATOM   252  C CE  . LYS A  1 258 ? 183.537 192.211 164.458 1.00 82.15  ? 258 LYS B CE  1 
ATOM   253  N NZ  . LYS A  1 258 ? 182.103 192.607 164.512 1.00 80.00  ? 258 LYS B NZ  1 
ATOM   254  N N   . LEU A  1 259 ? 186.003 197.051 163.787 1.00 99.91  ? 259 LEU B N   1 
ATOM   255  C CA  . LEU A  1 259 ? 184.895 197.980 163.611 1.00 98.24  ? 259 LEU B CA  1 
ATOM   256  C C   . LEU A  1 259 ? 184.814 198.357 162.140 1.00 99.27  ? 259 LEU B C   1 
ATOM   257  O O   . LEU A  1 259 ? 185.752 198.141 161.368 1.00 101.24 ? 259 LEU B O   1 
ATOM   258  C CB  . LEU A  1 259 ? 185.056 199.222 164.493 1.00 92.69  ? 259 LEU B CB  1 
ATOM   259  C CG  . LEU A  1 259 ? 183.760 199.840 165.021 1.00 94.55  ? 259 LEU B CG  1 
ATOM   260  C CD1 . LEU A  1 259 ? 182.837 198.767 165.582 1.00 93.60  ? 259 LEU B CD1 1 
ATOM   261  C CD2 . LEU A  1 259 ? 184.058 200.896 166.072 1.00 94.63  ? 259 LEU B CD2 1 
ATOM   262  N N   . GLU A  1 260 ? 183.672 198.921 161.759 1.00 112.84 ? 260 GLU B N   1 
ATOM   263  C CA  . GLU A  1 260 ? 183.445 199.413 160.407 1.00 112.77 ? 260 GLU B CA  1 
ATOM   264  C C   . GLU A  1 260 ? 183.171 200.910 160.470 1.00 114.92 ? 260 GLU B C   1 
ATOM   265  O O   . GLU A  1 260 ? 182.312 201.360 161.236 1.00 113.79 ? 260 GLU B O   1 
ATOM   266  C CB  . GLU A  1 260 ? 182.305 198.642 159.729 1.00 112.97 ? 260 GLU B CB  1 
ATOM   267  C CG  . GLU A  1 260 ? 180.904 198.902 160.268 1.00 115.05 ? 260 GLU B CG  1 
ATOM   268  C CD  . GLU A  1 260 ? 180.599 198.110 161.529 1.00 116.69 ? 260 GLU B CD  1 
ATOM   269  O OE1 . GLU A  1 260 ? 179.405 197.877 161.809 1.00 116.50 ? 260 GLU B OE1 1 
ATOM   270  O OE2 . GLU A  1 260 ? 181.548 197.716 162.239 1.00 116.49 ? 260 GLU B OE2 1 
ATOM   271  N N   . THR A  1 261 ? 183.933 201.679 159.698 1.00 128.32 ? 261 THR B N   1 
ATOM   272  C CA  . THR A  1 261 ? 183.846 203.140 159.714 1.00 128.29 ? 261 THR B CA  1 
ATOM   273  C C   . THR A  1 261 ? 182.927 203.670 158.618 1.00 126.80 ? 261 THR B C   1 
ATOM   274  O O   . THR A  1 261 ? 183.311 204.519 157.815 1.00 126.57 ? 261 THR B O   1 
ATOM   275  C CB  . THR A  1 261 ? 185.242 203.741 159.595 1.00 127.83 ? 261 THR B CB  1 
ATOM   276  O OG1 . THR A  1 261 ? 185.784 203.442 158.303 1.00 127.14 ? 261 THR B OG1 1 
ATOM   277  C CG2 . THR A  1 261 ? 186.158 203.172 160.669 1.00 127.12 ? 261 THR B CG2 1 
ATOM   278  N N   . ASP A  1 262 ? 181.693 203.167 158.576 1.00 123.30 ? 262 ASP B N   1 
ATOM   279  C CA  . ASP A  1 262 ? 180.694 203.664 157.643 1.00 123.31 ? 262 ASP B CA  1 
ATOM   280  C C   . ASP A  1 262 ? 179.374 204.008 158.317 1.00 121.27 ? 262 ASP B C   1 
ATOM   281  O O   . ASP A  1 262 ? 178.477 204.536 157.650 1.00 119.67 ? 262 ASP B O   1 
ATOM   282  C CB  . ASP A  1 262 ? 180.443 202.644 156.521 1.00 124.32 ? 262 ASP B CB  1 
ATOM   283  C CG  . ASP A  1 262 ? 179.828 201.355 157.029 1.00 124.49 ? 262 ASP B CG  1 
ATOM   284  O OD1 . ASP A  1 262 ? 179.919 201.089 158.245 1.00 124.66 ? 262 ASP B OD1 1 
ATOM   285  O OD2 . ASP A  1 262 ? 179.253 200.607 156.211 1.00 124.51 ? 262 ASP B OD2 1 
ATOM   286  N N   . ARG A  1 263 ? 179.231 203.728 159.610 1.00 114.39 ? 263 ARG B N   1 
ATOM   287  C CA  . ARG A  1 263 ? 178.018 204.020 160.355 1.00 113.50 ? 263 ARG B CA  1 
ATOM   288  C C   . ARG A  1 263 ? 178.377 204.784 161.620 1.00 111.05 ? 263 ARG B C   1 
ATOM   289  O O   . ARG A  1 263 ? 179.492 204.673 162.137 1.00 109.99 ? 263 ARG B O   1 
ATOM   290  C CB  . ARG A  1 263 ? 177.261 202.739 160.716 1.00 113.02 ? 263 ARG B CB  1 
ATOM   291  C CG  . ARG A  1 263 ? 178.165 201.572 161.068 1.00 114.82 ? 263 ARG B CG  1 
ATOM   292  C CD  . ARG A  1 263 ? 177.438 200.249 160.927 1.00 114.20 ? 263 ARG B CD  1 
ATOM   293  N NE  . ARG A  1 263 ? 176.887 200.052 159.592 1.00 115.14 ? 263 ARG B NE  1 
ATOM   294  C CZ  . ARG A  1 263 ? 175.612 199.789 159.341 1.00 115.79 ? 263 ARG B CZ  1 
ATOM   295  N NH1 . ARG A  1 263 ? 174.717 199.720 160.312 1.00 113.98 ? 263 ARG B NH1 1 
ATOM   296  N NH2 . ARG A  1 263 ? 175.226 199.589 158.085 1.00 115.59 ? 263 ARG B NH2 1 
ATOM   297  N N   . SER A  1 264 ? 177.418 205.560 162.117 1.00 92.35  ? 264 SER B N   1 
ATOM   298  C CA  . SER A  1 264 ? 177.644 206.393 163.290 1.00 92.60  ? 264 SER B CA  1 
ATOM   299  C C   . SER A  1 264 ? 177.590 205.539 164.551 1.00 91.67  ? 264 SER B C   1 
ATOM   300  O O   . SER A  1 264 ? 176.571 204.899 164.833 1.00 93.17  ? 264 SER B O   1 
ATOM   301  C CB  . SER A  1 264 ? 176.610 207.515 163.353 1.00 93.64  ? 264 SER B CB  1 
ATOM   302  O OG  . SER A  1 264 ? 176.993 208.506 164.290 1.00 90.10  ? 264 SER B OG  1 
ATOM   303  N N   . ILE A  1 265 ? 178.692 205.529 165.308 1.00 73.66  ? 265 ILE B N   1 
ATOM   304  C CA  . ILE A  1 265 ? 178.733 204.849 166.601 1.00 71.23  ? 265 ILE B CA  1 
ATOM   305  C C   . ILE A  1 265 ? 178.085 205.670 167.702 1.00 71.30  ? 265 ILE B C   1 
ATOM   306  O O   . ILE A  1 265 ? 177.936 205.178 168.828 1.00 73.89  ? 265 ILE B O   1 
ATOM   307  C CB  . ILE A  1 265 ? 180.193 204.521 166.976 1.00 72.71  ? 265 ILE B CB  1 
ATOM   308  C CG1 . ILE A  1 265 ? 180.258 203.381 167.995 1.00 73.39  ? 265 ILE B CG1 1 
ATOM   309  C CG2 . ILE A  1 265 ? 180.898 205.759 167.503 1.00 73.05  ? 265 ILE B CG2 1 
ATOM   310  C CD1 . ILE A  1 265 ? 181.650 202.832 168.209 1.00 72.14  ? 265 ILE B CD1 1 
ATOM   311  N N   . TRP A  1 266 ? 177.687 206.906 167.407 1.00 71.59  ? 266 TRP B N   1 
ATOM   312  C CA  . TRP A  1 266 ? 177.169 207.790 168.447 1.00 72.86  ? 266 TRP B CA  1 
ATOM   313  C C   . TRP A  1 266 ? 175.901 207.287 169.127 1.00 74.27  ? 266 TRP B C   1 
ATOM   314  O O   . TRP A  1 266 ? 175.793 207.463 170.353 1.00 82.58  ? 266 TRP B O   1 
ATOM   315  C CB  . TRP A  1 266 ? 176.962 209.195 167.870 1.00 74.68  ? 266 TRP B CB  1 
ATOM   316  C CG  . TRP A  1 266 ? 178.226 209.982 167.867 1.00 77.33  ? 266 TRP B CG  1 
ATOM   317  C CD1 . TRP A  1 266 ? 178.836 210.552 166.790 1.00 79.20  ? 266 TRP B CD1 1 
ATOM   318  C CD2 . TRP A  1 266 ? 179.058 210.266 168.998 1.00 73.74  ? 266 TRP B CD2 1 
ATOM   319  N NE1 . TRP A  1 266 ? 179.991 211.183 167.181 1.00 76.67  ? 266 TRP B NE1 1 
ATOM   320  C CE2 . TRP A  1 266 ? 180.148 211.021 168.532 1.00 79.31  ? 266 TRP B CE2 1 
ATOM   321  C CE3 . TRP A  1 266 ? 178.981 209.961 170.360 1.00 70.30  ? 266 TRP B CE3 1 
ATOM   322  C CZ2 . TRP A  1 266 ? 181.154 211.474 169.378 1.00 82.30  ? 266 TRP B CZ2 1 
ATOM   323  C CZ3 . TRP A  1 266 ? 179.980 210.410 171.197 1.00 74.45  ? 266 TRP B CZ3 1 
ATOM   324  C CH2 . TRP A  1 266 ? 181.052 211.159 170.704 1.00 78.89  ? 266 TRP B CH2 1 
ATOM   325  N N   . PRO A  1 267 ? 174.909 206.717 168.433 1.00 65.62  ? 267 PRO B N   1 
ATOM   326  C CA  . PRO A  1 267 ? 173.761 206.165 169.171 1.00 63.55  ? 267 PRO B CA  1 
ATOM   327  C C   . PRO A  1 267 ? 174.160 205.149 170.225 1.00 63.53  ? 267 PRO B C   1 
ATOM   328  O O   . PRO A  1 267 ? 173.635 205.190 171.342 1.00 66.34  ? 267 PRO B O   1 
ATOM   329  C CB  . PRO A  1 267 ? 172.908 205.536 168.064 1.00 63.47  ? 267 PRO B CB  1 
ATOM   330  C CG  . PRO A  1 267 ? 173.215 206.348 166.868 1.00 71.97  ? 267 PRO B CG  1 
ATOM   331  C CD  . PRO A  1 267 ? 174.670 206.704 166.978 1.00 71.11  ? 267 PRO B CD  1 
ATOM   332  N N   . LEU A  1 268 ? 175.107 204.261 169.915 1.00 59.69  ? 268 LEU B N   1 
ATOM   333  C CA  . LEU A  1 268 ? 175.552 203.276 170.897 1.00 61.62  ? 268 LEU B CA  1 
ATOM   334  C C   . LEU A  1 268 ? 176.215 203.949 172.092 1.00 58.89  ? 268 LEU B C   1 
ATOM   335  O O   . LEU A  1 268 ? 175.979 203.565 173.247 1.00 56.58  ? 268 LEU B O   1 
ATOM   336  C CB  . LEU A  1 268 ? 176.511 202.288 170.236 1.00 52.10  ? 268 LEU B CB  1 
ATOM   337  C CG  . LEU A  1 268 ? 176.817 200.995 170.987 1.00 46.90  ? 268 LEU B CG  1 
ATOM   338  C CD1 . LEU A  1 268 ? 175.727 199.974 170.735 1.00 50.60  ? 268 LEU B CD1 1 
ATOM   339  C CD2 . LEU A  1 268 ? 178.168 200.454 170.558 1.00 58.90  ? 268 LEU B CD2 1 
ATOM   340  N N   . ILE A  1 269 ? 177.051 204.955 171.830 1.00 58.87  ? 269 ILE B N   1 
ATOM   341  C CA  . ILE A  1 269 ? 177.716 205.680 172.907 1.00 56.86  ? 269 ILE B CA  1 
ATOM   342  C C   . ILE A  1 269 ? 176.687 206.347 173.806 1.00 50.87  ? 269 ILE B C   1 
ATOM   343  O O   . ILE A  1 269 ? 176.794 206.304 175.036 1.00 56.09  ? 269 ILE B O   1 
ATOM   344  C CB  . ILE A  1 269 ? 178.708 206.704 172.326 1.00 52.57  ? 269 ILE B CB  1 
ATOM   345  C CG1 . ILE A  1 269 ? 179.869 205.993 171.630 1.00 56.89  ? 269 ILE B CG1 1 
ATOM   346  C CG2 . ILE A  1 269 ? 179.221 207.626 173.414 1.00 49.21  ? 269 ILE B CG2 1 
ATOM   347  C CD1 . ILE A  1 269 ? 180.903 205.433 172.580 1.00 58.75  ? 269 ILE B CD1 1 
ATOM   348  N N   . ARG A  1 270 ? 175.671 206.968 173.207 1.00 49.47  ? 270 ARG B N   1 
ATOM   349  C CA  . ARG A  1 270 ? 174.661 207.658 173.998 1.00 52.23  ? 270 ARG B CA  1 
ATOM   350  C C   . ARG A  1 270 ? 173.786 206.681 174.771 1.00 59.63  ? 270 ARG B C   1 
ATOM   351  O O   . ARG A  1 270 ? 173.293 207.019 175.852 1.00 72.91  ? 270 ARG B O   1 
ATOM   352  C CB  . ARG A  1 270 ? 173.807 208.547 173.097 1.00 49.54  ? 270 ARG B CB  1 
ATOM   353  C CG  . ARG A  1 270 ? 173.341 209.830 173.759 1.00 55.17  ? 270 ARG B CG  1 
ATOM   354  C CD  . ARG A  1 270 ? 173.692 211.049 172.922 1.00 57.90  ? 270 ARG B CD  1 
ATOM   355  N NE  . ARG A  1 270 ? 173.297 210.895 171.528 1.00 59.33  ? 270 ARG B NE  1 
ATOM   356  C CZ  . ARG A  1 270 ? 174.031 211.285 170.495 1.00 60.36  ? 270 ARG B CZ  1 
ATOM   357  N NH1 . ARG A  1 270 ? 175.206 211.867 170.663 1.00 63.62  ? 270 ARG B NH1 1 
ATOM   358  N NH2 . ARG A  1 270 ? 173.572 211.089 169.262 1.00 59.00  ? 270 ARG B NH2 1 
ATOM   359  N N   . ILE A  1 271 ? 173.570 205.477 174.239 1.00 47.45  ? 271 ILE B N   1 
ATOM   360  C CA  . ILE A  1 271 ? 172.800 204.483 174.981 1.00 44.55  ? 271 ILE B CA  1 
ATOM   361  C C   . ILE A  1 271 ? 173.592 203.972 176.179 1.00 53.30  ? 271 ILE B C   1 
ATOM   362  O O   . ILE A  1 271 ? 173.047 203.821 177.279 1.00 50.85  ? 271 ILE B O   1 
ATOM   363  C CB  . ILE A  1 271 ? 172.371 203.325 174.064 1.00 49.24  ? 271 ILE B CB  1 
ATOM   364  C CG1 . ILE A  1 271 ? 171.524 203.834 172.899 1.00 53.33  ? 271 ILE B CG1 1 
ATOM   365  C CG2 . ILE A  1 271 ? 171.604 202.285 174.855 1.00 52.45  ? 271 ILE B CG2 1 
ATOM   366  C CD1 . ILE A  1 271 ? 170.131 204.217 173.272 1.00 59.17  ? 271 ILE B CD1 1 
ATOM   367  N N   . TYR A  1 272 ? 174.884 203.696 175.993 1.00 57.93  ? 272 TYR B N   1 
ATOM   368  C CA  . TYR A  1 272 ? 175.667 203.045 177.038 1.00 52.76  ? 272 TYR B CA  1 
ATOM   369  C C   . TYR A  1 272 ? 176.341 204.013 178.002 1.00 52.85  ? 272 TYR B C   1 
ATOM   370  O O   . TYR A  1 272 ? 176.874 203.568 179.028 1.00 55.29  ? 272 TYR B O   1 
ATOM   371  C CB  . TYR A  1 272 ? 176.724 202.138 176.407 1.00 41.23  ? 272 TYR B CB  1 
ATOM   372  C CG  . TYR A  1 272 ? 176.170 200.805 175.972 1.00 44.89  ? 272 TYR B CG  1 
ATOM   373  C CD1 . TYR A  1 272 ? 175.764 199.864 176.905 1.00 46.01  ? 272 TYR B CD1 1 
ATOM   374  C CD2 . TYR A  1 272 ? 176.036 200.495 174.629 1.00 48.43  ? 272 TYR B CD2 1 
ATOM   375  C CE1 . TYR A  1 272 ? 175.251 198.651 176.513 1.00 50.04  ? 272 TYR B CE1 1 
ATOM   376  C CE2 . TYR A  1 272 ? 175.525 199.283 174.228 1.00 43.64  ? 272 TYR B CE2 1 
ATOM   377  C CZ  . TYR A  1 272 ? 175.135 198.365 175.173 1.00 44.37  ? 272 TYR B CZ  1 
ATOM   378  O OH  . TYR A  1 272 ? 174.624 197.153 174.775 1.00 50.60  ? 272 TYR B OH  1 
ATOM   379  N N   . ARG A  1 273 ? 176.329 205.316 177.711 1.00 48.97  ? 273 ARG B N   1 
ATOM   380  C CA  . ARG A  1 273 ? 176.958 206.271 178.615 1.00 41.06  ? 273 ARG B CA  1 
ATOM   381  C C   . ARG A  1 273 ? 176.241 206.317 179.955 1.00 42.45  ? 273 ARG B C   1 
ATOM   382  O O   . ARG A  1 273 ? 176.882 206.447 181.001 1.00 57.29  ? 273 ARG B O   1 
ATOM   383  C CB  . ARG A  1 273 ? 176.994 207.656 177.973 1.00 40.35  ? 273 ARG B CB  1 
ATOM   384  C CG  . ARG A  1 273 ? 177.773 208.686 178.765 1.00 41.96  ? 273 ARG B CG  1 
ATOM   385  C CD  . ARG A  1 273 ? 177.780 210.025 178.054 1.00 45.77  ? 273 ARG B CD  1 
ATOM   386  N NE  . ARG A  1 273 ? 176.428 210.492 177.777 1.00 46.98  ? 273 ARG B NE  1 
ATOM   387  C CZ  . ARG A  1 273 ? 176.076 211.166 176.691 1.00 53.29  ? 273 ARG B CZ  1 
ATOM   388  N NH1 . ARG A  1 273 ? 176.957 211.475 175.755 1.00 54.25  ? 273 ARG B NH1 1 
ATOM   389  N NH2 . ARG A  1 273 ? 174.809 211.539 176.541 1.00 54.44  ? 273 ARG B NH2 1 
ATOM   390  N N   . GLY A  1 274 ? 174.911 206.214 179.947 1.00 27.65  ? 274 GLY B N   1 
ATOM   391  C CA  . GLY A  1 274 ? 174.180 206.198 181.204 1.00 44.52  ? 274 GLY B CA  1 
ATOM   392  C C   . GLY A  1 274 ? 174.544 205.009 182.071 1.00 42.54  ? 274 GLY B C   1 
ATOM   393  O O   . GLY A  1 274 ? 174.763 205.149 183.279 1.00 46.65  ? 274 GLY B O   1 
ATOM   394  N N   . GLY A  1 275 ? 174.624 203.824 181.466 1.00 35.37  ? 275 GLY B N   1 
ATOM   395  C CA  . GLY A  1 275 ? 175.042 202.654 182.215 1.00 40.02  ? 275 GLY B CA  1 
ATOM   396  C C   . GLY A  1 275 ? 176.449 202.787 182.761 1.00 38.84  ? 275 GLY B C   1 
ATOM   397  O O   . GLY A  1 275 ? 176.709 202.453 183.920 1.00 50.90  ? 275 GLY B O   1 
ATOM   398  N N   . PHE A  1 276 ? 177.376 203.288 181.940 1.00 36.35  ? 276 PHE B N   1 
ATOM   399  C CA  . PHE A  1 276 ? 178.745 203.461 182.416 1.00 29.64  ? 276 PHE B CA  1 
ATOM   400  C C   . PHE A  1 276 ? 178.808 204.453 183.567 1.00 33.22  ? 276 PHE B C   1 
ATOM   401  O O   . PHE A  1 276 ? 179.551 204.247 184.534 1.00 47.12  ? 276 PHE B O   1 
ATOM   402  C CB  . PHE A  1 276 ? 179.659 203.922 181.285 1.00 40.47  ? 276 PHE B CB  1 
ATOM   403  C CG  . PHE A  1 276 ? 180.981 204.441 181.765 1.00 34.95  ? 276 PHE B CG  1 
ATOM   404  C CD1 . PHE A  1 276 ? 181.878 203.600 182.397 1.00 39.39  ? 276 PHE B CD1 1 
ATOM   405  C CD2 . PHE A  1 276 ? 181.317 205.772 181.604 1.00 33.42  ? 276 PHE B CD2 1 
ATOM   406  C CE1 . PHE A  1 276 ? 183.090 204.073 182.849 1.00 42.14  ? 276 PHE B CE1 1 
ATOM   407  C CE2 . PHE A  1 276 ? 182.528 206.252 182.054 1.00 39.06  ? 276 PHE B CE2 1 
ATOM   408  C CZ  . PHE A  1 276 ? 183.416 205.401 182.677 1.00 43.69  ? 276 PHE B CZ  1 
ATOM   409  N N   . LEU A  1 277 ? 178.045 205.544 183.475 1.00 39.10  ? 277 LEU B N   1 
ATOM   410  C CA  . LEU A  1 277 ? 178.034 206.529 184.548 1.00 40.98  ? 277 LEU B CA  1 
ATOM   411  C C   . LEU A  1 277 ? 177.455 205.941 185.824 1.00 43.75  ? 277 LEU B C   1 
ATOM   412  O O   . LEU A  1 277 ? 177.922 206.251 186.923 1.00 39.42  ? 277 LEU B O   1 
ATOM   413  C CB  . LEU A  1 277 ? 177.250 207.768 184.123 1.00 24.41  ? 277 LEU B CB  1 
ATOM   414  C CG  . LEU A  1 277 ? 177.940 208.633 183.070 1.00 31.77  ? 277 LEU B CG  1 
ATOM   415  C CD1 . LEU A  1 277 ? 176.919 209.430 182.292 1.00 37.16  ? 277 LEU B CD1 1 
ATOM   416  C CD2 . LEU A  1 277 ? 178.963 209.547 183.706 1.00 44.31  ? 277 LEU B CD2 1 
ATOM   417  N N   . LEU A  1 278 ? 176.437 205.086 185.703 1.00 45.10  ? 278 LEU B N   1 
ATOM   418  C CA  . LEU A  1 278 ? 175.896 204.436 186.892 1.00 39.69  ? 278 LEU B CA  1 
ATOM   419  C C   . LEU A  1 278 ? 176.923 203.501 187.525 1.00 36.85  ? 278 LEU B C   1 
ATOM   420  O O   . LEU A  1 278 ? 177.063 203.464 188.755 1.00 44.09  ? 278 LEU B O   1 
ATOM   421  C CB  . LEU A  1 278 ? 174.610 203.689 186.538 1.00 37.96  ? 278 LEU B CB  1 
ATOM   422  C CG  . LEU A  1 278 ? 173.608 203.396 187.658 1.00 37.83  ? 278 LEU B CG  1 
ATOM   423  C CD1 . LEU A  1 278 ? 172.262 203.078 187.052 1.00 47.84  ? 278 LEU B CD1 1 
ATOM   424  C CD2 . LEU A  1 278 ? 174.054 202.244 188.541 1.00 41.20  ? 278 LEU B CD2 1 
ATOM   425  N N   . ILE A  1 279 ? 177.656 202.744 186.703 1.00 33.26  ? 279 ILE B N   1 
ATOM   426  C CA  . ILE A  1 279 ? 178.693 201.860 187.241 1.00 29.50  ? 279 ILE B CA  1 
ATOM   427  C C   . ILE A  1 279 ? 179.752 202.676 187.968 1.00 33.98  ? 279 ILE B C   1 
ATOM   428  O O   . ILE A  1 279 ? 180.174 202.339 189.083 1.00 49.70  ? 279 ILE B O   1 
ATOM   429  C CB  . ILE A  1 279 ? 179.327 201.011 186.124 1.00 32.32  ? 279 ILE B CB  1 
ATOM   430  C CG1 . ILE A  1 279 ? 178.266 200.295 185.293 1.00 33.18  ? 279 ILE B CG1 1 
ATOM   431  C CG2 . ILE A  1 279 ? 180.305 200.010 186.713 1.00 31.08  ? 279 ILE B CG2 1 
ATOM   432  C CD1 . ILE A  1 279 ? 177.209 199.621 186.098 1.00 38.98  ? 279 ILE B CD1 1 
ATOM   433  N N   . GLU A  1 280 ? 180.201 203.763 187.338 1.00 30.79  ? 280 GLU B N   1 
ATOM   434  C CA  . GLU A  1 280 ? 181.219 204.607 187.950 1.00 33.20  ? 280 GLU B CA  1 
ATOM   435  C C   . GLU A  1 280 ? 180.709 205.233 189.239 1.00 41.71  ? 280 GLU B C   1 
ATOM   436  O O   . GLU A  1 280 ? 181.454 205.346 190.217 1.00 43.32  ? 280 GLU B O   1 
ATOM   437  C CB  . GLU A  1 280 ? 181.665 205.687 186.968 1.00 31.43  ? 280 GLU B CB  1 
ATOM   438  C CG  . GLU A  1 280 ? 182.387 206.847 187.618 1.00 36.32  ? 280 GLU B CG  1 
ATOM   439  C CD  . GLU A  1 280 ? 182.739 207.932 186.631 1.00 40.82  ? 280 GLU B CD  1 
ATOM   440  O OE1 . GLU A  1 280 ? 182.362 207.805 185.449 1.00 36.41  ? 280 GLU B OE1 1 
ATOM   441  O OE2 . GLU A  1 280 ? 183.397 208.910 187.035 1.00 49.37  ? 280 GLU B OE2 1 
ATOM   442  N N   . PHE A  1 281 ? 179.442 205.651 189.260 1.00 35.37  ? 281 PHE B N   1 
ATOM   443  C CA  . PHE A  1 281 ? 178.884 206.239 190.470 1.00 29.87  ? 281 PHE B CA  1 
ATOM   444  C C   . PHE A  1 281 ? 178.841 205.226 191.602 1.00 36.81  ? 281 PHE B C   1 
ATOM   445  O O   . PHE A  1 281 ? 179.170 205.555 192.742 1.00 46.10  ? 281 PHE B O   1 
ATOM   446  C CB  . PHE A  1 281 ? 177.488 206.793 190.202 1.00 28.73  ? 281 PHE B CB  1 
ATOM   447  C CG  . PHE A  1 281 ? 176.771 207.231 191.444 1.00 38.14  ? 281 PHE B CG  1 
ATOM   448  C CD1 . PHE A  1 281 ? 177.252 208.287 192.197 1.00 37.12  ? 281 PHE B CD1 1 
ATOM   449  C CD2 . PHE A  1 281 ? 175.628 206.580 191.867 1.00 39.08  ? 281 PHE B CD2 1 
ATOM   450  C CE1 . PHE A  1 281 ? 176.602 208.689 193.342 1.00 38.70  ? 281 PHE B CE1 1 
ATOM   451  C CE2 . PHE A  1 281 ? 174.974 206.978 193.013 1.00 38.91  ? 281 PHE B CE2 1 
ATOM   452  C CZ  . PHE A  1 281 ? 175.462 208.033 193.751 1.00 38.22  ? 281 PHE B CZ  1 
ATOM   453  N N   . LEU A  1 282 ? 178.440 203.988 191.309 1.00 36.88  ? 282 LEU B N   1 
ATOM   454  C CA  . LEU A  1 282 ? 178.407 202.969 192.356 1.00 25.79  ? 282 LEU B CA  1 
ATOM   455  C C   . LEU A  1 282 ? 179.808 202.655 192.873 1.00 31.70  ? 282 LEU B C   1 
ATOM   456  O O   . LEU A  1 282 ? 180.013 202.508 194.085 1.00 46.07  ? 282 LEU B O   1 
ATOM   457  C CB  . LEU A  1 282 ? 177.724 201.705 191.837 1.00 27.28  ? 282 LEU B CB  1 
ATOM   458  C CG  . LEU A  1 282 ? 176.261 201.504 192.236 1.00 22.99  ? 282 LEU B CG  1 
ATOM   459  C CD1 . LEU A  1 282 ? 176.163 201.124 193.698 1.00 31.54  ? 282 LEU B CD1 1 
ATOM   460  C CD2 . LEU A  1 282 ? 175.441 202.747 191.957 1.00 26.23  ? 282 LEU B CD2 1 
ATOM   461  N N   . PHE A  1 283 ? 180.789 202.563 191.973 1.00 29.99  ? 283 PHE B N   1 
ATOM   462  C CA  . PHE A  1 283 ? 182.160 202.281 192.392 1.00 21.82  ? 283 PHE B CA  1 
ATOM   463  C C   . PHE A  1 283 ? 182.723 203.421 193.242 1.00 30.41  ? 283 PHE B C   1 
ATOM   464  O O   . PHE A  1 283 ? 183.306 203.194 194.314 1.00 37.31  ? 283 PHE B O   1 
ATOM   465  C CB  . PHE A  1 283 ? 183.012 202.019 191.147 1.00 26.42  ? 283 PHE B CB  1 
ATOM   466  C CG  . PHE A  1 283 ? 184.479 202.266 191.329 1.00 31.70  ? 283 PHE B CG  1 
ATOM   467  C CD1 . PHE A  1 283 ? 185.214 201.539 192.247 1.00 37.37  ? 283 PHE B CD1 1 
ATOM   468  C CD2 . PHE A  1 283 ? 185.133 203.203 190.547 1.00 39.12  ? 283 PHE B CD2 1 
ATOM   469  C CE1 . PHE A  1 283 ? 186.566 201.762 192.402 1.00 36.35  ? 283 PHE B CE1 1 
ATOM   470  C CE2 . PHE A  1 283 ? 186.484 203.428 190.696 1.00 40.66  ? 283 PHE B CE2 1 
ATOM   471  C CZ  . PHE A  1 283 ? 187.202 202.704 191.623 1.00 40.79  ? 283 PHE B CZ  1 
ATOM   472  N N   . LEU A  1 284 ? 182.530 204.663 192.793 1.00 34.79  ? 284 LEU B N   1 
ATOM   473  C CA  . LEU A  1 284 ? 182.997 205.812 193.558 1.00 30.20  ? 284 LEU B CA  1 
ATOM   474  C C   . LEU A  1 284 ? 182.234 205.962 194.867 1.00 39.68  ? 284 LEU B C   1 
ATOM   475  O O   . LEU A  1 284 ? 182.783 206.474 195.844 1.00 43.16  ? 284 LEU B O   1 
ATOM   476  C CB  . LEU A  1 284 ? 182.879 207.081 192.716 1.00 16.27  ? 284 LEU B CB  1 
ATOM   477  C CG  . LEU A  1 284 ? 183.792 207.145 191.490 1.00 20.43  ? 284 LEU B CG  1 
ATOM   478  C CD1 . LEU A  1 284 ? 183.811 208.538 190.900 1.00 20.20  ? 284 LEU B CD1 1 
ATOM   479  C CD2 . LEU A  1 284 ? 185.197 206.702 191.846 1.00 38.59  ? 284 LEU B CD2 1 
ATOM   480  N N   . LEU A  1 285 ? 180.981 205.510 194.917 1.00 43.84  ? 285 LEU B N   1 
ATOM   481  C CA  . LEU A  1 285 ? 180.235 205.527 196.168 1.00 36.49  ? 285 LEU B CA  1 
ATOM   482  C C   . LEU A  1 285 ? 180.760 204.483 197.142 1.00 39.26  ? 285 LEU B C   1 
ATOM   483  O O   . LEU A  1 285 ? 180.753 204.710 198.355 1.00 49.28  ? 285 LEU B O   1 
ATOM   484  C CB  . LEU A  1 285 ? 178.752 205.305 195.890 1.00 25.09  ? 285 LEU B CB  1 
ATOM   485  C CG  . LEU A  1 285 ? 177.788 205.591 197.036 1.00 29.88  ? 285 LEU B CG  1 
ATOM   486  C CD1 . LEU A  1 285 ? 178.122 206.912 197.698 1.00 36.23  ? 285 LEU B CD1 1 
ATOM   487  C CD2 . LEU A  1 285 ? 176.379 205.610 196.501 1.00 29.60  ? 285 LEU B CD2 1 
ATOM   488  N N   . GLY A  1 286 ? 181.206 203.334 196.637 1.00 32.72  ? 286 GLY B N   1 
ATOM   489  C CA  . GLY A  1 286 ? 181.921 202.403 197.494 1.00 30.03  ? 286 GLY B CA  1 
ATOM   490  C C   . GLY A  1 286 ? 183.193 203.011 198.055 1.00 35.42  ? 286 GLY B C   1 
ATOM   491  O O   . GLY A  1 286 ? 183.498 202.862 199.245 1.00 53.39  ? 286 GLY B O   1 
ATOM   492  N N   . ILE A  1 287 ? 183.947 203.716 197.207 1.00 27.44  ? 287 ILE B N   1 
ATOM   493  C CA  . ILE A  1 287 ? 185.127 204.431 197.694 1.00 22.34  ? 287 ILE B CA  1 
ATOM   494  C C   . ILE A  1 287 ? 184.732 205.440 198.766 1.00 41.59  ? 287 ILE B C   1 
ATOM   495  O O   . ILE A  1 287 ? 185.419 205.592 199.784 1.00 43.75  ? 287 ILE B O   1 
ATOM   496  C CB  . ILE A  1 287 ? 185.868 205.117 196.532 1.00 26.55  ? 287 ILE B CB  1 
ATOM   497  C CG1 . ILE A  1 287 ? 186.445 204.088 195.566 1.00 37.88  ? 287 ILE B CG1 1 
ATOM   498  C CG2 . ILE A  1 287 ? 186.982 206.000 197.062 1.00 28.11  ? 287 ILE B CG2 1 
ATOM   499  C CD1 . ILE A  1 287 ? 187.197 204.713 194.418 1.00 34.53  ? 287 ILE B CD1 1 
ATOM   500  N N   . ASN A  1 288 ? 183.623 206.150 198.548 1.00 45.59  ? 288 ASN B N   1 
ATOM   501  C CA  . ASN A  1 288 ? 183.151 207.134 199.516 1.00 29.17  ? 288 ASN B CA  1 
ATOM   502  C C   . ASN A  1 288 ? 182.797 206.481 200.842 1.00 41.90  ? 288 ASN B C   1 
ATOM   503  O O   . ASN A  1 288 ? 183.091 207.029 201.907 1.00 50.04  ? 288 ASN B O   1 
ATOM   504  C CB  . ASN A  1 288 ? 181.938 207.879 198.964 1.00 16.73  ? 288 ASN B CB  1 
ATOM   505  C CG  . ASN A  1 288 ? 182.320 209.074 198.130 1.00 26.68  ? 288 ASN B CG  1 
ATOM   506  O OD1 . ASN A  1 288 ? 181.742 209.316 197.074 1.00 36.20  ? 288 ASN B OD1 1 
ATOM   507  N ND2 . ASN A  1 288 ? 183.299 209.831 198.599 1.00 42.61  ? 288 ASN B ND2 1 
ATOM   508  N N   . THR A  1 289 ? 182.132 205.326 200.798 1.00 38.29  ? 289 THR B N   1 
ATOM   509  C CA  . THR A  1 289 ? 181.779 204.630 202.031 1.00 30.02  ? 289 THR B CA  1 
ATOM   510  C C   . THR A  1 289 ? 183.026 204.192 202.786 1.00 31.55  ? 289 THR B C   1 
ATOM   511  O O   . THR A  1 289 ? 183.094 204.317 204.015 1.00 42.33  ? 289 THR B O   1 
ATOM   512  C CB  . THR A  1 289 ? 180.888 203.430 201.722 1.00 29.76  ? 289 THR B CB  1 
ATOM   513  O OG1 . THR A  1 289 ? 179.704 203.876 201.053 1.00 48.16  ? 289 THR B OG1 1 
ATOM   514  C CG2 . THR A  1 289 ? 180.495 202.721 203.004 1.00 39.52  ? 289 THR B CG2 1 
ATOM   515  N N   . TYR A  1 290 ? 184.028 203.682 202.066 1.00 34.81  ? 290 TYR B N   1 
ATOM   516  C CA  . TYR A  1 290 ? 185.286 203.320 202.716 1.00 38.49  ? 290 TYR B CA  1 
ATOM   517  C C   . TYR A  1 290 ? 185.937 204.536 203.362 1.00 40.32  ? 290 TYR B C   1 
ATOM   518  O O   . TYR A  1 290 ? 186.422 204.471 204.500 1.00 42.88  ? 290 TYR B O   1 
ATOM   519  C CB  . TYR A  1 290 ? 186.235 202.677 201.705 1.00 45.45  ? 290 TYR B CB  1 
ATOM   520  C CG  . TYR A  1 290 ? 187.699 202.850 202.049 1.00 43.70  ? 290 TYR B CG  1 
ATOM   521  C CD1 . TYR A  1 290 ? 188.321 202.014 202.963 1.00 41.78  ? 290 TYR B CD1 1 
ATOM   522  C CD2 . TYR A  1 290 ? 188.460 203.846 201.451 1.00 50.93  ? 290 TYR B CD2 1 
ATOM   523  C CE1 . TYR A  1 290 ? 189.655 202.169 203.277 1.00 48.52  ? 290 TYR B CE1 1 
ATOM   524  C CE2 . TYR A  1 290 ? 189.794 204.009 201.761 1.00 49.68  ? 290 TYR B CE2 1 
ATOM   525  C CZ  . TYR A  1 290 ? 190.386 203.168 202.675 1.00 51.40  ? 290 TYR B CZ  1 
ATOM   526  O OH  . TYR A  1 290 ? 191.716 203.326 202.985 1.00 54.80  ? 290 TYR B OH  1 
ATOM   527  N N   . GLY A  1 291 ? 185.965 205.657 202.639 1.00 38.06  ? 291 GLY B N   1 
ATOM   528  C CA  . GLY A  1 291 ? 186.556 206.865 203.186 1.00 39.50  ? 291 GLY B CA  1 
ATOM   529  C C   . GLY A  1 291 ? 185.814 207.372 204.406 1.00 40.58  ? 291 GLY B C   1 
ATOM   530  O O   . GLY A  1 291 ? 186.428 207.821 205.375 1.00 45.19  ? 291 GLY B O   1 
ATOM   531  N N   . TRP A  1 292 ? 184.483 207.310 204.374 1.00 35.24  ? 292 TRP B N   1 
ATOM   532  C CA  . TRP A  1 292 ? 183.695 207.718 205.529 1.00 39.74  ? 292 TRP B CA  1 
ATOM   533  C C   . TRP A  1 292 ? 183.976 206.825 206.727 1.00 47.74  ? 292 TRP B C   1 
ATOM   534  O O   . TRP A  1 292 ? 184.120 207.313 207.854 1.00 50.05  ? 292 TRP B O   1 
ATOM   535  C CB  . TRP A  1 292 ? 182.203 207.696 205.199 1.00 39.45  ? 292 TRP B CB  1 
ATOM   536  C CG  . TRP A  1 292 ? 181.795 208.646 204.127 1.00 34.15  ? 292 TRP B CG  1 
ATOM   537  C CD1 . TRP A  1 292 ? 182.421 209.802 203.775 1.00 33.62  ? 292 TRP B CD1 1 
ATOM   538  C CD2 . TRP A  1 292 ? 180.659 208.526 203.267 1.00 29.66  ? 292 TRP B CD2 1 
ATOM   539  N NE1 . TRP A  1 292 ? 181.748 210.408 202.744 1.00 36.43  ? 292 TRP B NE1 1 
ATOM   540  C CE2 . TRP A  1 292 ? 180.661 209.642 202.414 1.00 37.77  ? 292 TRP B CE2 1 
ATOM   541  C CE3 . TRP A  1 292 ? 179.641 207.580 203.134 1.00 35.92  ? 292 TRP B CE3 1 
ATOM   542  C CZ2 . TRP A  1 292 ? 179.686 209.839 201.442 1.00 48.16  ? 292 TRP B CZ2 1 
ATOM   543  C CZ3 . TRP A  1 292 ? 178.674 207.776 202.170 1.00 44.21  ? 292 TRP B CZ3 1 
ATOM   544  C CH2 . TRP A  1 292 ? 178.703 208.896 201.336 1.00 45.93  ? 292 TRP B CH2 1 
ATOM   545  N N   . ARG A  1 293 ? 184.052 205.513 206.506 1.00 53.45  ? 293 ARG B N   1 
ATOM   546  C CA  . ARG A  1 293 ? 184.285 204.601 207.619 1.00 49.63  ? 293 ARG B CA  1 
ATOM   547  C C   . ARG A  1 293 ? 185.661 204.815 208.238 1.00 52.27  ? 293 ARG B C   1 
ATOM   548  O O   . ARG A  1 293 ? 185.792 204.859 209.466 1.00 55.66  ? 293 ARG B O   1 
ATOM   549  C CB  . ARG A  1 293 ? 184.119 203.155 207.158 1.00 49.89  ? 293 ARG B CB  1 
ATOM   550  C CG  . ARG A  1 293 ? 184.012 202.166 208.299 1.00 53.90  ? 293 ARG B CG  1 
ATOM   551  C CD  . ARG A  1 293 ? 183.391 200.859 207.832 1.00 54.98  ? 293 ARG B CD  1 
ATOM   552  N NE  . ARG A  1 293 ? 181.936 200.916 207.714 1.00 62.79  ? 293 ARG B NE  1 
ATOM   553  C CZ  . ARG A  1 293 ? 181.095 201.364 208.640 1.00 63.46  ? 293 ARG B CZ  1 
ATOM   554  N NH1 . ARG A  1 293 ? 181.505 201.709 209.851 1.00 61.42  ? 293 ARG B NH1 1 
ATOM   555  N NH2 . ARG A  1 293 ? 179.801 201.444 208.352 1.00 60.11  ? 293 ARG B NH2 1 
ATOM   556  N N   . GLN A  1 294 ? 186.698 204.961 207.410 1.00 48.40  ? 294 GLN B N   1 
ATOM   557  C CA  . GLN A  1 294 ? 188.046 205.083 207.959 1.00 49.96  ? 294 GLN B CA  1 
ATOM   558  C C   . GLN A  1 294 ? 188.301 206.470 208.537 1.00 51.24  ? 294 GLN B C   1 
ATOM   559  O O   . GLN A  1 294 ? 189.006 206.606 209.543 1.00 54.05  ? 294 GLN B O   1 
ATOM   560  C CB  . GLN A  1 294 ? 189.083 204.742 206.891 1.00 45.00  ? 294 GLN B CB  1 
ATOM   561  C CG  . GLN A  1 294 ? 189.103 203.280 206.435 1.00 51.36  ? 294 GLN B CG  1 
ATOM   562  C CD  . GLN A  1 294 ? 188.834 202.251 207.535 1.00 58.11  ? 294 GLN B CD  1 
ATOM   563  O OE1 . GLN A  1 294 ? 189.155 202.456 208.707 1.00 58.29  ? 294 GLN B OE1 1 
ATOM   564  N NE2 . GLN A  1 294 ? 188.233 201.132 207.148 1.00 54.45  ? 294 GLN B NE2 1 
ATOM   565  N N   . ALA A  1 295 ? 187.748 207.511 207.913 1.00 44.89  ? 295 ALA B N   1 
ATOM   566  C CA  . ALA A  1 295 ? 188.021 208.873 208.358 1.00 46.69  ? 295 ALA B CA  1 
ATOM   567  C C   . ALA A  1 295 ? 187.424 209.147 209.732 1.00 52.21  ? 295 ALA B C   1 
ATOM   568  O O   . ALA A  1 295 ? 188.062 209.788 210.574 1.00 54.42  ? 295 ALA B O   1 
ATOM   569  C CB  . ALA A  1 295 ? 187.486 209.869 207.334 1.00 46.50  ? 295 ALA B CB  1 
ATOM   570  N N   . GLY A  1 296 ? 186.206 208.675 209.978 1.00 47.06  ? 296 GLY B N   1 
ATOM   571  C CA  . GLY A  1 296 ? 185.559 208.912 211.252 1.00 46.00  ? 296 GLY B CA  1 
ATOM   572  C C   . GLY A  1 296 ? 184.153 209.457 211.120 1.00 52.46  ? 296 GLY B C   1 
ATOM   573  O O   . GLY A  1 296 ? 183.351 209.344 212.051 1.00 58.83  ? 296 GLY B O   1 
ATOM   574  N N   . VAL A  1 297 ? 183.843 210.057 209.971 1.00 49.62  ? 297 VAL B N   1 
ATOM   575  C CA  . VAL A  1 297 ? 182.491 210.548 209.725 1.00 46.14  ? 297 VAL B CA  1 
ATOM   576  C C   . VAL A  1 297 ? 181.517 209.379 209.726 1.00 51.02  ? 297 VAL B C   1 
ATOM   577  O O   . VAL A  1 297 ? 181.695 208.396 208.998 1.00 53.15  ? 297 VAL B O   1 
ATOM   578  C CB  . VAL A  1 297 ? 182.438 211.354 208.422 1.00 42.55  ? 297 VAL B CB  1 
ATOM   579  C CG1 . VAL A  1 297 ? 183.048 210.582 207.294 1.00 49.22  ? 297 VAL B CG1 1 
ATOM   580  C CG2 . VAL A  1 297 ? 181.001 211.655 208.062 1.00 47.44  ? 297 VAL B CG2 1 
ATOM   581  N N   . ASN A  1 298 ? 180.487 209.476 210.564 1.00 50.32  ? 298 ASN B N   1 
ATOM   582  C CA  . ASN A  1 298 ? 179.511 208.403 210.749 1.00 47.11  ? 298 ASN B CA  1 
ATOM   583  C C   . ASN A  1 298 ? 178.376 208.616 209.759 1.00 43.47  ? 298 ASN B C   1 
ATOM   584  O O   . ASN A  1 298 ? 177.428 209.356 210.018 1.00 49.70  ? 298 ASN B O   1 
ATOM   585  C CB  . ASN A  1 298 ? 179.006 208.381 212.186 1.00 46.91  ? 298 ASN B CB  1 
ATOM   586  C CG  . ASN A  1 298 ? 178.132 207.179 212.479 1.00 54.84  ? 298 ASN B CG  1 
ATOM   587  O OD1 . ASN A  1 298 ? 177.896 206.339 211.611 1.00 59.92  ? 298 ASN B OD1 1 
ATOM   588  N ND2 . ASN A  1 298 ? 177.641 207.094 213.709 1.00 55.69  ? 298 ASN B ND2 1 
ATOM   589  N N   . HIS A  1 299 ? 178.470 207.952 208.607 1.00 42.99  ? 299 HIS B N   1 
ATOM   590  C CA  . HIS A  1 299 ? 177.417 208.063 207.607 1.00 44.39  ? 299 HIS B CA  1 
ATOM   591  C C   . HIS A  1 299 ? 176.169 207.281 207.991 1.00 52.31  ? 299 HIS B C   1 
ATOM   592  O O   . HIS A  1 299 ? 175.083 207.596 207.497 1.00 61.19  ? 299 HIS B O   1 
ATOM   593  C CB  . HIS A  1 299 ? 177.927 207.592 206.247 1.00 39.21  ? 299 HIS B CB  1 
ATOM   594  C CG  . HIS A  1 299 ? 178.118 206.111 206.154 1.00 44.78  ? 299 HIS B CG  1 
ATOM   595  N ND1 . HIS A  1 299 ? 177.371 205.317 205.311 1.00 51.34  ? 299 HIS B ND1 1 
ATOM   596  C CD2 . HIS A  1 299 ? 178.972 205.280 206.795 1.00 54.85  ? 299 HIS B CD2 1 
ATOM   597  C CE1 . HIS A  1 299 ? 177.756 204.060 205.438 1.00 51.92  ? 299 HIS B CE1 1 
ATOM   598  N NE2 . HIS A  1 299 ? 178.726 204.011 206.333 1.00 57.25  ? 299 HIS B NE2 1 
ATOM   599  N N   . VAL A  1 300 ? 176.296 206.272 208.854 1.00 52.42  ? 300 VAL B N   1 
ATOM   600  C CA  . VAL A  1 300 ? 175.132 205.488 209.256 1.00 50.67  ? 300 VAL B CA  1 
ATOM   601  C C   . VAL A  1 300 ? 174.166 206.346 210.063 1.00 49.38  ? 300 VAL B C   1 
ATOM   602  O O   . VAL A  1 300 ? 172.957 206.361 209.803 1.00 51.23  ? 300 VAL B O   1 
ATOM   603  C CB  . VAL A  1 300 ? 175.572 204.240 210.042 1.00 51.18  ? 300 VAL B CB  1 
ATOM   604  C CG1 . VAL A  1 300 ? 174.426 203.712 210.888 1.00 54.12  ? 300 VAL B CG1 1 
ATOM   605  C CG2 . VAL A  1 300 ? 176.069 203.168 209.091 1.00 51.48  ? 300 VAL B CG2 1 
ATOM   606  N N   . LEU A  1 301 ? 174.683 207.072 211.056 1.00 46.10  ? 301 LEU B N   1 
ATOM   607  C CA  . LEU A  1 301 ? 173.832 207.955 211.846 1.00 51.23  ? 301 LEU B CA  1 
ATOM   608  C C   . LEU A  1 301 ? 173.279 209.094 210.999 1.00 47.92  ? 301 LEU B C   1 
ATOM   609  O O   . LEU A  1 301 ? 172.108 209.466 211.136 1.00 46.38  ? 301 LEU B O   1 
ATOM   610  C CB  . LEU A  1 301 ? 174.611 208.504 213.039 1.00 48.44  ? 301 LEU B CB  1 
ATOM   611  C CG  . LEU A  1 301 ? 174.039 209.756 213.704 1.00 49.31  ? 301 LEU B CG  1 
ATOM   612  C CD1 . LEU A  1 301 ? 172.787 209.420 214.497 1.00 44.17  ? 301 LEU B CD1 1 
ATOM   613  C CD2 . LEU A  1 301 ? 175.081 210.413 214.592 1.00 50.39  ? 301 LEU B CD2 1 
ATOM   614  N N   . ILE A  1 302 ? 174.109 209.662 210.123 1.00 47.01  ? 302 ILE B N   1 
ATOM   615  C CA  . ILE A  1 302 ? 173.674 210.789 209.302 1.00 36.17  ? 302 ILE B CA  1 
ATOM   616  C C   . ILE A  1 302 ? 172.563 210.357 208.353 1.00 40.52  ? 302 ILE B C   1 
ATOM   617  O O   . ILE A  1 302 ? 171.539 211.036 208.218 1.00 54.32  ? 302 ILE B O   1 
ATOM   618  C CB  . ILE A  1 302 ? 174.871 211.387 208.542 1.00 32.78  ? 302 ILE B CB  1 
ATOM   619  C CG1 . ILE A  1 302 ? 175.817 212.084 209.515 1.00 42.69  ? 302 ILE B CG1 1 
ATOM   620  C CG2 . ILE A  1 302 ? 174.402 212.374 207.504 1.00 44.83  ? 302 ILE B CG2 1 
ATOM   621  C CD1 . ILE A  1 302 ? 177.069 212.610 208.866 1.00 43.59  ? 302 ILE B CD1 1 
ATOM   622  N N   . PHE A  1 303 ? 172.743 209.216 207.689 1.00 30.31  ? 303 PHE B N   1 
ATOM   623  C CA  . PHE A  1 303 ? 171.729 208.697 206.781 1.00 41.13  ? 303 PHE B CA  1 
ATOM   624  C C   . PHE A  1 303 ? 170.527 208.104 207.504 1.00 50.99  ? 303 PHE B C   1 
ATOM   625  O O   . PHE A  1 303 ? 169.534 207.780 206.844 1.00 51.26  ? 303 PHE B O   1 
ATOM   626  C CB  . PHE A  1 303 ? 172.331 207.632 205.864 1.00 38.36  ? 303 PHE B CB  1 
ATOM   627  C CG  . PHE A  1 303 ? 172.998 208.186 204.643 1.00 34.49  ? 303 PHE B CG  1 
ATOM   628  C CD1 . PHE A  1 303 ? 174.242 208.778 204.727 1.00 40.94  ? 303 PHE B CD1 1 
ATOM   629  C CD2 . PHE A  1 303 ? 172.383 208.103 203.410 1.00 33.23  ? 303 PHE B CD2 1 
ATOM   630  C CE1 . PHE A  1 303 ? 174.857 209.281 203.607 1.00 37.59  ? 303 PHE B CE1 1 
ATOM   631  C CE2 . PHE A  1 303 ? 172.995 208.605 202.288 1.00 36.52  ? 303 PHE B CE2 1 
ATOM   632  C CZ  . PHE A  1 303 ? 174.233 209.195 202.386 1.00 37.91  ? 303 PHE B CZ  1 
ATOM   633  N N   . GLU A  1 304 ? 170.598 207.948 208.828 1.00 58.80  ? 304 GLU B N   1 
ATOM   634  C CA  . GLU A  1 304 ? 169.539 207.314 209.615 1.00 58.30  ? 304 GLU B CA  1 
ATOM   635  C C   . GLU A  1 304 ? 169.289 205.882 209.140 1.00 63.44  ? 304 GLU B C   1 
ATOM   636  O O   . GLU A  1 304 ? 168.187 205.521 208.724 1.00 61.95  ? 304 GLU B O   1 
ATOM   637  C CB  . GLU A  1 304 ? 168.251 208.141 209.582 1.00 51.24  ? 304 GLU B CB  1 
ATOM   638  C CG  . GLU A  1 304 ? 168.407 209.551 210.125 1.00 58.28  ? 304 GLU B CG  1 
ATOM   639  C CD  . GLU A  1 304 ? 167.883 210.604 209.170 1.00 65.05  ? 304 GLU B CD  1 
ATOM   640  O OE1 . GLU A  1 304 ? 167.233 210.230 208.172 1.00 61.14  ? 304 GLU B OE1 1 
ATOM   641  O OE2 . GLU A  1 304 ? 168.123 211.805 209.417 1.00 60.11  ? 304 GLU B OE2 1 
ATOM   642  N N   . LEU A  1 305 ? 170.335 205.065 209.206 1.00 62.95  ? 305 LEU B N   1 
ATOM   643  C CA  . LEU A  1 305 ? 170.279 203.670 208.799 1.00 63.18  ? 305 LEU B CA  1 
ATOM   644  C C   . LEU A  1 305 ? 170.386 202.754 210.011 1.00 61.84  ? 305 LEU B C   1 
ATOM   645  O O   . LEU A  1 305 ? 170.930 203.123 211.054 1.00 56.80  ? 305 LEU B O   1 
ATOM   646  C CB  . LEU A  1 305 ? 171.401 203.345 207.810 1.00 62.15  ? 305 LEU B CB  1 
ATOM   647  C CG  . LEU A  1 305 ? 171.460 204.163 206.522 1.00 57.33  ? 305 LEU B CG  1 
ATOM   648  C CD1 . LEU A  1 305 ? 172.605 203.687 205.647 1.00 54.07  ? 305 LEU B CD1 1 
ATOM   649  C CD2 . LEU A  1 305 ? 170.142 204.078 205.778 1.00 51.27  ? 305 LEU B CD2 1 
ATOM   650  N N   . ASN A  1 306 ? 169.857 201.549 209.860 1.00 76.25  ? 306 ASN B N   1 
ATOM   651  C CA  . ASN A  1 306 ? 169.992 200.541 210.903 1.00 75.21  ? 306 ASN B CA  1 
ATOM   652  C C   . ASN A  1 306 ? 171.430 200.043 210.931 1.00 78.99  ? 306 ASN B C   1 
ATOM   653  O O   . ASN A  1 306 ? 171.928 199.562 209.904 1.00 80.60  ? 306 ASN B O   1 
ATOM   654  C CB  . ASN A  1 306 ? 169.026 199.386 210.661 1.00 77.10  ? 306 ASN B CB  1 
ATOM   655  C CG  . ASN A  1 306 ? 167.574 199.816 210.728 1.00 76.17  ? 306 ASN B CG  1 
ATOM   656  O OD1 . ASN A  1 306 ? 167.271 200.981 210.985 1.00 75.14  ? 306 ASN B OD1 1 
ATOM   657  N ND2 . ASN A  1 306 ? 166.666 198.875 210.495 1.00 75.56  ? 306 ASN B ND2 1 
ATOM   658  N N   . PRO A  1 307 ? 172.132 200.140 212.062 1.00 83.20  ? 307 PRO B N   1 
ATOM   659  C CA  . PRO A  1 307 ? 173.553 199.756 212.083 1.00 84.58  ? 307 PRO B CA  1 
ATOM   660  C C   . PRO A  1 307 ? 173.803 198.285 211.797 1.00 84.53  ? 307 PRO B C   1 
ATOM   661  O O   . PRO A  1 307 ? 174.936 197.923 211.457 1.00 82.39  ? 307 PRO B O   1 
ATOM   662  C CB  . PRO A  1 307 ? 173.997 200.129 213.505 1.00 81.34  ? 307 PRO B CB  1 
ATOM   663  C CG  . PRO A  1 307 ? 172.984 201.126 213.977 1.00 76.64  ? 307 PRO B CG  1 
ATOM   664  C CD  . PRO A  1 307 ? 171.694 200.714 213.344 1.00 76.29  ? 307 PRO B CD  1 
ATOM   665  N N   . ARG A  1 308 ? 172.792 197.426 211.930 1.00 88.51  ? 308 ARG B N   1 
ATOM   666  C CA  . ARG A  1 308 ? 173.011 195.994 211.755 1.00 88.39  ? 308 ARG B CA  1 
ATOM   667  C C   . ARG A  1 308 ? 173.235 195.635 210.290 1.00 86.08  ? 308 ARG B C   1 
ATOM   668  O O   . ARG A  1 308 ? 174.146 194.866 209.963 1.00 88.34  ? 308 ARG B O   1 
ATOM   669  C CB  . ARG A  1 308 ? 171.828 195.211 212.324 1.00 94.16  ? 308 ARG B CB  1 
ATOM   670  C CG  . ARG A  1 308 ? 171.376 195.676 213.698 1.00 91.40  ? 308 ARG B CG  1 
ATOM   671  C CD  . ARG A  1 308 ? 172.471 195.481 214.733 1.00 91.04  ? 308 ARG B CD  1 
ATOM   672  N NE  . ARG A  1 308 ? 171.951 195.546 216.093 1.00 91.21  ? 308 ARG B NE  1 
ATOM   673  C CZ  . ARG A  1 308 ? 171.399 194.524 216.733 1.00 90.74  ? 308 ARG B CZ  1 
ATOM   674  N NH1 . ARG A  1 308 ? 171.281 193.335 216.163 1.00 89.74  ? 308 ARG B NH1 1 
ATOM   675  N NH2 . ARG A  1 308 ? 170.957 194.697 217.975 1.00 88.62  ? 308 ARG B NH2 1 
ATOM   676  N N   . SER A  1 309 ? 172.418 196.182 209.393 1.00 73.26  ? 309 SER B N   1 
ATOM   677  C CA  . SER A  1 309 ? 172.428 195.786 207.991 1.00 78.48  ? 309 SER B CA  1 
ATOM   678  C C   . SER A  1 309 ? 173.003 196.853 207.069 1.00 78.15  ? 309 SER B C   1 
ATOM   679  O O   . SER A  1 309 ? 172.729 196.826 205.865 1.00 80.32  ? 309 SER B O   1 
ATOM   680  C CB  . SER A  1 309 ? 171.013 195.420 207.539 1.00 75.52  ? 309 SER B CB  1 
ATOM   681  O OG  . SER A  1 309 ? 171.006 195.005 206.184 1.00 74.21  ? 309 SER B OG  1 
ATOM   682  N N   . ASN A  1 310 ? 173.785 197.790 207.599 1.00 74.17  ? 310 ASN B N   1 
ATOM   683  C CA  . ASN A  1 310 ? 174.390 198.814 206.759 1.00 74.33  ? 310 ASN B CA  1 
ATOM   684  C C   . ASN A  1 310 ? 175.385 198.190 205.787 1.00 74.69  ? 310 ASN B C   1 
ATOM   685  O O   . ASN A  1 310 ? 176.096 197.238 206.122 1.00 78.86  ? 310 ASN B O   1 
ATOM   686  C CB  . ASN A  1 310 ? 175.080 199.865 207.626 1.00 74.51  ? 310 ASN B CB  1 
ATOM   687  C CG  . ASN A  1 310 ? 176.233 199.295 208.420 1.00 74.48  ? 310 ASN B CG  1 
ATOM   688  O OD1 . ASN A  1 310 ? 176.185 198.152 208.873 1.00 78.67  ? 310 ASN B OD1 1 
ATOM   689  N ND2 . ASN A  1 310 ? 177.278 200.090 208.597 1.00 70.12  ? 310 ASN B ND2 1 
ATOM   690  N N   . LEU A  1 311 ? 175.430 198.731 204.572 1.00 63.71  ? 311 LEU B N   1 
ATOM   691  C CA  . LEU A  1 311 ? 176.290 198.193 203.526 1.00 67.05  ? 311 LEU B CA  1 
ATOM   692  C C   . LEU A  1 311 ? 177.713 198.705 203.704 1.00 70.91  ? 311 LEU B C   1 
ATOM   693  O O   . LEU A  1 311 ? 177.943 199.918 203.737 1.00 73.15  ? 311 LEU B O   1 
ATOM   694  C CB  . LEU A  1 311 ? 175.762 198.577 202.146 1.00 62.17  ? 311 LEU B CB  1 
ATOM   695  C CG  . LEU A  1 311 ? 174.701 197.672 201.524 1.00 67.92  ? 311 LEU B CG  1 
ATOM   696  C CD1 . LEU A  1 311 ? 174.697 197.823 200.012 1.00 63.72  ? 311 LEU B CD1 1 
ATOM   697  C CD2 . LEU A  1 311 ? 174.921 196.222 201.924 1.00 66.31  ? 311 LEU B CD2 1 
ATOM   698  N N   . SER A  1 312 ? 178.664 197.783 203.816 1.00 62.56  ? 312 SER B N   1 
ATOM   699  C CA  . SER A  1 312 ? 180.066 198.155 203.772 1.00 60.39  ? 312 SER B CA  1 
ATOM   700  C C   . SER A  1 312 ? 180.470 198.470 202.334 1.00 52.34  ? 312 SER B C   1 
ATOM   701  O O   . SER A  1 312 ? 179.738 198.195 201.380 1.00 49.93  ? 312 SER B O   1 
ATOM   702  C CB  . SER A  1 312 ? 180.937 197.038 204.345 1.00 61.33  ? 312 SER B CB  1 
ATOM   703  O OG  . SER A  1 312 ? 182.246 197.504 204.619 1.00 62.77  ? 312 SER B OG  1 
ATOM   704  N N   . HIS A  1 313 ? 181.655 199.064 202.181 1.00 46.86  ? 313 HIS B N   1 
ATOM   705  C CA  . HIS A  1 313 ? 182.126 199.411 200.845 1.00 52.52  ? 313 HIS B CA  1 
ATOM   706  C C   . HIS A  1 313 ? 182.355 198.181 199.980 1.00 51.74  ? 313 HIS B C   1 
ATOM   707  O O   . HIS A  1 313 ? 182.336 198.291 198.749 1.00 55.33  ? 313 HIS B O   1 
ATOM   708  C CB  . HIS A  1 313 ? 183.409 200.237 200.929 1.00 54.29  ? 313 HIS B CB  1 
ATOM   709  C CG  . HIS A  1 313 ? 184.499 199.591 201.724 1.00 46.86  ? 313 HIS B CG  1 
ATOM   710  N ND1 . HIS A  1 313 ? 184.485 199.536 203.100 1.00 53.17  ? 313 HIS B ND1 1 
ATOM   711  C CD2 . HIS A  1 313 ? 185.645 198.986 201.334 1.00 47.52  ? 313 HIS B CD2 1 
ATOM   712  C CE1 . HIS A  1 313 ? 185.573 198.918 203.525 1.00 58.27  ? 313 HIS B CE1 1 
ATOM   713  N NE2 . HIS A  1 313 ? 186.293 198.574 202.473 1.00 61.24  ? 313 HIS B NE2 1 
ATOM   714  N N   . GLN A  1 314 ? 182.560 197.013 200.594 1.00 50.39  ? 314 GLN B N   1 
ATOM   715  C CA  . GLN A  1 314 ? 182.740 195.791 199.819 1.00 54.68  ? 314 GLN B CA  1 
ATOM   716  C C   . GLN A  1 314 ? 181.490 195.464 199.013 1.00 59.77  ? 314 GLN B C   1 
ATOM   717  O O   . GLN A  1 314 ? 181.581 195.064 197.848 1.00 61.71  ? 314 GLN B O   1 
ATOM   718  C CB  . GLN A  1 314 ? 183.093 194.629 200.747 1.00 54.98  ? 314 GLN B CB  1 
ATOM   719  C CG  . GLN A  1 314 ? 184.488 194.684 201.366 1.00 55.20  ? 314 GLN B CG  1 
ATOM   720  C CD  . GLN A  1 314 ? 185.619 194.705 200.352 1.00 55.61  ? 314 GLN B CD  1 
ATOM   721  O OE1 . GLN A  1 314 ? 185.411 194.526 199.153 1.00 47.11  ? 314 GLN B OE1 1 
ATOM   722  N NE2 . GLN A  1 314 ? 186.832 194.922 200.839 1.00 54.50  ? 314 GLN B NE2 1 
ATOM   723  N N   . HIS A  1 315 ? 180.312 195.632 199.615 1.00 53.98  ? 315 HIS B N   1 
ATOM   724  C CA  . HIS A  1 315 ? 179.071 195.316 198.916 1.00 47.54  ? 315 HIS B CA  1 
ATOM   725  C C   . HIS A  1 315 ? 178.814 196.282 197.766 1.00 51.96  ? 315 HIS B C   1 
ATOM   726  O O   . HIS A  1 315 ? 178.367 195.869 196.690 1.00 57.14  ? 315 HIS B O   1 
ATOM   727  C CB  . HIS A  1 315 ? 177.903 195.324 199.899 1.00 47.73  ? 315 HIS B CB  1 
ATOM   728  C CG  . HIS A  1 315 ? 178.124 194.464 201.104 1.00 56.23  ? 315 HIS B CG  1 
ATOM   729  N ND1 . HIS A  1 315 ? 178.994 194.809 202.116 1.00 59.56  ? 315 HIS B ND1 1 
ATOM   730  C CD2 . HIS A  1 315 ? 177.590 193.272 201.458 1.00 57.67  ? 315 HIS B CD2 1 
ATOM   731  C CE1 . HIS A  1 315 ? 178.985 193.867 203.042 1.00 60.90  ? 315 HIS B CE1 1 
ATOM   732  N NE2 . HIS A  1 315 ? 178.141 192.923 202.667 1.00 61.21  ? 315 HIS B NE2 1 
ATOM   733  N N   . LEU A  1 316 ? 179.077 197.574 197.975 1.00 46.71  ? 316 LEU B N   1 
ATOM   734  C CA  . LEU A  1 316 ? 178.926 198.537 196.888 1.00 44.51  ? 316 LEU B CA  1 
ATOM   735  C C   . LEU A  1 316 ? 179.910 198.247 195.764 1.00 37.28  ? 316 LEU B C   1 
ATOM   736  O O   . LEU A  1 316 ? 179.552 198.315 194.582 1.00 41.54  ? 316 LEU B O   1 
ATOM   737  C CB  . LEU A  1 316 ? 179.113 199.959 197.413 1.00 43.82  ? 316 LEU B CB  1 
ATOM   738  C CG  . LEU A  1 316 ? 177.942 200.549 198.198 1.00 36.36  ? 316 LEU B CG  1 
ATOM   739  C CD1 . LEU A  1 316 ? 178.347 201.856 198.845 1.00 36.13  ? 316 LEU B CD1 1 
ATOM   740  C CD2 . LEU A  1 316 ? 176.742 200.749 197.296 1.00 37.34  ? 316 LEU B CD2 1 
ATOM   741  N N   . PHE A  1 317 ? 181.153 197.909 196.117 1.00 33.94  ? 317 PHE B N   1 
ATOM   742  C CA  . PHE A  1 317 ? 182.136 197.536 195.107 1.00 40.16  ? 317 PHE B CA  1 
ATOM   743  C C   . PHE A  1 317 ? 181.679 196.312 194.326 1.00 44.36  ? 317 PHE B C   1 
ATOM   744  O O   . PHE A  1 317 ? 181.832 196.255 193.103 1.00 44.16  ? 317 PHE B O   1 
ATOM   745  C CB  . PHE A  1 317 ? 183.486 197.263 195.766 1.00 45.14  ? 317 PHE B CB  1 
ATOM   746  C CG  . PHE A  1 317 ? 184.280 198.495 196.068 1.00 36.29  ? 317 PHE B CG  1 
ATOM   747  C CD1 . PHE A  1 317 ? 184.277 199.567 195.200 1.00 31.08  ? 317 PHE B CD1 1 
ATOM   748  C CD2 . PHE A  1 317 ? 185.047 198.570 197.215 1.00 47.03  ? 317 PHE B CD2 1 
ATOM   749  C CE1 . PHE A  1 317 ? 185.014 200.695 195.479 1.00 46.27  ? 317 PHE B CE1 1 
ATOM   750  C CE2 . PHE A  1 317 ? 185.786 199.694 197.497 1.00 44.04  ? 317 PHE B CE2 1 
ATOM   751  C CZ  . PHE A  1 317 ? 185.770 200.758 196.628 1.00 46.23  ? 317 PHE B CZ  1 
ATOM   752  N N   . GLU A  1 318 ? 181.114 195.322 195.018 1.00 51.53  ? 318 GLU B N   1 
ATOM   753  C CA  . GLU A  1 318 ? 180.666 194.102 194.357 1.00 49.30  ? 318 GLU B CA  1 
ATOM   754  C C   . GLU A  1 318 ? 179.481 194.364 193.435 1.00 49.77  ? 318 GLU B C   1 
ATOM   755  O O   . GLU A  1 318 ? 179.421 193.818 192.327 1.00 50.10  ? 318 GLU B O   1 
ATOM   756  C CB  . GLU A  1 318 ? 180.315 193.051 195.408 1.00 42.24  ? 318 GLU B CB  1 
ATOM   757  C CG  . GLU A  1 318 ? 179.457 191.914 194.904 1.00 50.77  ? 318 GLU B CG  1 
ATOM   758  C CD  . GLU A  1 318 ? 178.776 191.174 196.033 1.00 59.45  ? 318 GLU B CD  1 
ATOM   759  O OE1 . GLU A  1 318 ? 179.486 190.579 196.870 1.00 62.04  ? 318 GLU B OE1 1 
ATOM   760  O OE2 . GLU A  1 318 ? 177.530 191.197 196.092 1.00 54.87  ? 318 GLU B OE2 1 
ATOM   761  N N   . ILE A  1 319 ? 178.527 195.188 193.874 1.00 48.99  ? 319 ILE B N   1 
ATOM   762  C CA  . ILE A  1 319 ? 177.388 195.532 193.023 1.00 46.09  ? 319 ILE B CA  1 
ATOM   763  C C   . ILE A  1 319 ? 177.863 196.278 191.783 1.00 50.17  ? 319 ILE B C   1 
ATOM   764  O O   . ILE A  1 319 ? 177.436 195.990 190.655 1.00 48.42  ? 319 ILE B O   1 
ATOM   765  C CB  . ILE A  1 319 ? 176.357 196.358 193.812 1.00 43.43  ? 319 ILE B CB  1 
ATOM   766  C CG1 . ILE A  1 319 ? 175.547 195.462 194.743 1.00 52.36  ? 319 ILE B CG1 1 
ATOM   767  C CG2 . ILE A  1 319 ? 175.427 197.093 192.866 1.00 44.99  ? 319 ILE B CG2 1 
ATOM   768  C CD1 . ILE A  1 319 ? 174.825 196.223 195.830 1.00 53.41  ? 319 ILE B CD1 1 
ATOM   769  N N   . ALA A  1 320 ? 178.759 197.250 191.976 1.00 45.83  ? 320 ALA B N   1 
ATOM   770  C CA  . ALA A  1 320 ? 179.305 197.988 190.845 1.00 37.44  ? 320 ALA B CA  1 
ATOM   771  C C   . ALA A  1 320 ? 180.037 197.059 189.892 1.00 49.70  ? 320 ALA B C   1 
ATOM   772  O O   . ALA A  1 320 ? 179.886 197.169 188.673 1.00 57.70  ? 320 ALA B O   1 
ATOM   773  C CB  . ALA A  1 320 ? 180.238 199.090 191.340 1.00 40.07  ? 320 ALA B CB  1 
ATOM   774  N N   . GLY A  1 321 ? 180.819 196.122 190.430 1.00 51.25  ? 321 GLY B N   1 
ATOM   775  C CA  . GLY A  1 321 ? 181.543 195.195 189.579 1.00 40.17  ? 321 GLY B CA  1 
ATOM   776  C C   . GLY A  1 321 ? 180.629 194.280 188.790 1.00 41.15  ? 321 GLY B C   1 
ATOM   777  O O   . GLY A  1 321 ? 180.857 194.039 187.606 1.00 48.06  ? 321 GLY B O   1 
ATOM   778  N N   . PHE A  1 322 ? 179.584 193.755 189.432 1.00 38.76  ? 322 PHE B N   1 
ATOM   779  C CA  . PHE A  1 322 ? 178.660 192.862 188.737 1.00 36.75  ? 322 PHE B CA  1 
ATOM   780  C C   . PHE A  1 322 ? 177.906 193.597 187.635 1.00 46.49  ? 322 PHE B C   1 
ATOM   781  O O   . PHE A  1 322 ? 177.777 193.098 186.505 1.00 60.52  ? 322 PHE B O   1 
ATOM   782  C CB  . PHE A  1 322 ? 177.689 192.242 189.741 1.00 41.11  ? 322 PHE B CB  1 
ATOM   783  C CG  . PHE A  1 322 ? 176.522 191.546 189.108 1.00 47.66  ? 322 PHE B CG  1 
ATOM   784  C CD1 . PHE A  1 322 ? 176.717 190.553 188.165 1.00 53.08  ? 322 PHE B CD1 1 
ATOM   785  C CD2 . PHE A  1 322 ? 175.227 191.877 189.467 1.00 50.65  ? 322 PHE B CD2 1 
ATOM   786  C CE1 . PHE A  1 322 ? 175.643 189.909 187.586 1.00 52.17  ? 322 PHE B CE1 1 
ATOM   787  C CE2 . PHE A  1 322 ? 174.149 191.237 188.892 1.00 53.11  ? 322 PHE B CE2 1 
ATOM   788  C CZ  . PHE A  1 322 ? 174.357 190.251 187.951 1.00 59.81  ? 322 PHE B CZ  1 
ATOM   789  N N   . LEU A  1 323 ? 177.404 194.795 187.939 1.00 52.21  ? 323 LEU B N   1 
ATOM   790  C CA  . LEU A  1 323 ? 176.714 195.559 186.909 1.00 52.84  ? 323 LEU B CA  1 
ATOM   791  C C   . LEU A  1 323 ? 177.674 195.997 185.809 1.00 42.31  ? 323 LEU B C   1 
ATOM   792  O O   . LEU A  1 323 ? 177.272 196.107 184.648 1.00 41.70  ? 323 LEU B O   1 
ATOM   793  C CB  . LEU A  1 323 ? 176.002 196.754 187.534 1.00 49.99  ? 323 LEU B CB  1 
ATOM   794  C CG  . LEU A  1 323 ? 174.914 196.417 188.554 1.00 45.67  ? 323 LEU B CG  1 
ATOM   795  C CD1 . LEU A  1 323 ? 174.242 197.681 189.054 1.00 45.00  ? 323 LEU B CD1 1 
ATOM   796  C CD2 . LEU A  1 323 ? 173.895 195.469 187.951 1.00 50.23  ? 323 LEU B CD2 1 
ATOM   797  N N   . GLY A  1 324 ? 178.945 196.222 186.145 1.00 42.94  ? 324 GLY B N   1 
ATOM   798  C CA  . GLY A  1 324 ? 179.936 196.484 185.117 1.00 44.96  ? 324 GLY B CA  1 
ATOM   799  C C   . GLY A  1 324 ? 180.204 195.274 184.245 1.00 45.94  ? 324 GLY B C   1 
ATOM   800  O O   . GLY A  1 324 ? 180.451 195.408 183.046 1.00 51.99  ? 324 GLY B O   1 
ATOM   801  N N   . ILE A  1 325 ? 180.172 194.079 184.838 1.00 45.68  ? 325 ILE B N   1 
ATOM   802  C CA  . ILE A  1 325 ? 180.282 192.854 184.049 1.00 44.83  ? 325 ILE B CA  1 
ATOM   803  C C   . ILE A  1 325 ? 179.158 192.798 183.031 1.00 44.27  ? 325 ILE B C   1 
ATOM   804  O O   . ILE A  1 325 ? 179.374 192.522 181.845 1.00 49.19  ? 325 ILE B O   1 
ATOM   805  C CB  . ILE A  1 325 ? 180.256 191.610 184.957 1.00 45.76  ? 325 ILE B CB  1 
ATOM   806  C CG1 . ILE A  1 325 ? 181.446 191.580 185.911 1.00 45.28  ? 325 ILE B CG1 1 
ATOM   807  C CG2 . ILE A  1 325 ? 180.229 190.347 184.118 1.00 43.13  ? 325 ILE B CG2 1 
ATOM   808  C CD1 . ILE A  1 325 ? 182.689 192.152 185.338 1.00 48.15  ? 325 ILE B CD1 1 
ATOM   809  N N   . LEU A  1 326 ? 177.934 193.068 183.487 1.00 41.14  ? 326 LEU B N   1 
ATOM   810  C CA  . LEU A  1 326 ? 176.790 193.032 182.580 1.00 42.61  ? 326 LEU B CA  1 
ATOM   811  C C   . LEU A  1 326 ? 176.896 194.105 181.502 1.00 47.98  ? 326 LEU B C   1 
ATOM   812  O O   . LEU A  1 326 ? 176.592 193.851 180.330 1.00 43.65  ? 326 LEU B O   1 
ATOM   813  C CB  . LEU A  1 326 ? 175.497 193.184 183.370 1.00 35.64  ? 326 LEU B CB  1 
ATOM   814  C CG  . LEU A  1 326 ? 175.246 192.010 184.308 1.00 44.07  ? 326 LEU B CG  1 
ATOM   815  C CD1 . LEU A  1 326 ? 173.931 192.198 185.000 1.00 40.85  ? 326 LEU B CD1 1 
ATOM   816  C CD2 . LEU A  1 326 ? 175.267 190.702 183.541 1.00 47.98  ? 326 LEU B CD2 1 
ATOM   817  N N   . TRP A  1 327 ? 177.324 195.312 181.878 1.00 49.25  ? 327 TRP B N   1 
ATOM   818  C CA  . TRP A  1 327 ? 177.477 196.387 180.905 1.00 41.89  ? 327 TRP B CA  1 
ATOM   819  C C   . TRP A  1 327 ? 178.529 196.042 179.859 1.00 42.12  ? 327 TRP B C   1 
ATOM   820  O O   . TRP A  1 327 ? 178.321 196.262 178.660 1.00 51.44  ? 327 TRP B O   1 
ATOM   821  C CB  . TRP A  1 327 ? 177.838 197.686 181.625 1.00 39.12  ? 327 TRP B CB  1 
ATOM   822  C CG  . TRP A  1 327 ? 178.082 198.840 180.714 1.00 31.05  ? 327 TRP B CG  1 
ATOM   823  C CD1 . TRP A  1 327 ? 177.143 199.598 180.085 1.00 33.24  ? 327 TRP B CD1 1 
ATOM   824  C CD2 . TRP A  1 327 ? 179.353 199.378 180.334 1.00 38.65  ? 327 TRP B CD2 1 
ATOM   825  N NE1 . TRP A  1 327 ? 177.748 200.572 179.331 1.00 46.04  ? 327 TRP B NE1 1 
ATOM   826  C CE2 . TRP A  1 327 ? 179.106 200.457 179.467 1.00 44.81  ? 327 TRP B CE2 1 
ATOM   827  C CE3 . TRP A  1 327 ? 180.675 199.049 180.640 1.00 39.80  ? 327 TRP B CE3 1 
ATOM   828  C CZ2 . TRP A  1 327 ? 180.131 201.209 178.904 1.00 45.06  ? 327 TRP B CZ2 1 
ATOM   829  C CZ3 . TRP A  1 327 ? 181.690 199.796 180.079 1.00 33.77  ? 327 TRP B CZ3 1 
ATOM   830  C CH2 . TRP A  1 327 ? 181.414 200.863 179.221 1.00 39.53  ? 327 TRP B CH2 1 
ATOM   831  N N   . CYS A  1 328 ? 179.665 195.495 180.296 1.00 37.52  ? 328 CYS B N   1 
ATOM   832  C CA  . CYS A  1 328 ? 180.719 195.118 179.362 1.00 34.17  ? 328 CYS B CA  1 
ATOM   833  C C   . CYS A  1 328 ? 180.262 193.998 178.442 1.00 43.70  ? 328 CYS B C   1 
ATOM   834  O O   . CYS A  1 328 ? 180.571 194.006 177.246 1.00 47.29  ? 328 CYS B O   1 
ATOM   835  C CB  . CYS A  1 328 ? 181.974 194.704 180.127 1.00 35.24  ? 328 CYS B CB  1 
ATOM   836  S SG  . CYS A  1 328 ? 182.960 196.085 180.726 1.00 45.24  ? 328 CYS B SG  1 
ATOM   837  N N   . LEU A  1 329 ? 179.524 193.024 178.978 1.00 51.40  ? 329 LEU B N   1 
ATOM   838  C CA  . LEU A  1 329 ? 179.019 191.942 178.140 1.00 52.46  ? 329 LEU B CA  1 
ATOM   839  C C   . LEU A  1 329 ? 178.025 192.460 177.108 1.00 52.01  ? 329 LEU B C   1 
ATOM   840  O O   . LEU A  1 329 ? 178.063 192.049 175.942 1.00 52.72  ? 329 LEU B O   1 
ATOM   841  C CB  . LEU A  1 329 ? 178.386 190.860 179.010 1.00 48.48  ? 329 LEU B CB  1 
ATOM   842  C CG  . LEU A  1 329 ? 179.388 189.919 179.678 1.00 40.38  ? 329 LEU B CG  1 
ATOM   843  C CD1 . LEU A  1 329 ? 178.720 189.101 180.767 1.00 49.39  ? 329 LEU B CD1 1 
ATOM   844  C CD2 . LEU A  1 329 ? 180.032 189.018 178.642 1.00 46.03  ? 329 LEU B CD2 1 
ATOM   845  N N   . SER A  1 330 ? 177.134 193.367 177.513 1.00 43.92  ? 330 SER B N   1 
ATOM   846  C CA  . SER A  1 330 ? 176.178 193.932 176.566 1.00 50.11  ? 330 SER B CA  1 
ATOM   847  C C   . SER A  1 330 ? 176.882 194.742 175.484 1.00 54.43  ? 330 SER B C   1 
ATOM   848  O O   . SER A  1 330 ? 176.537 194.645 174.300 1.00 57.99  ? 330 SER B O   1 
ATOM   849  C CB  . SER A  1 330 ? 175.157 194.793 177.305 1.00 50.47  ? 330 SER B CB  1 
ATOM   850  O OG  . SER A  1 330 ? 174.438 195.609 176.400 1.00 54.20  ? 330 SER B OG  1 
ATOM   851  N N   . LEU A  1 331 ? 177.877 195.545 175.868 1.00 49.18  ? 331 LEU B N   1 
ATOM   852  C CA  . LEU A  1 331 ? 178.624 196.313 174.878 1.00 45.42  ? 331 LEU B CA  1 
ATOM   853  C C   . LEU A  1 331 ? 179.386 195.398 173.926 1.00 58.05  ? 331 LEU B C   1 
ATOM   854  O O   . LEU A  1 331 ? 179.446 195.659 172.718 1.00 61.95  ? 331 LEU B O   1 
ATOM   855  C CB  . LEU A  1 331 ? 179.574 197.284 175.579 1.00 42.40  ? 331 LEU B CB  1 
ATOM   856  C CG  . LEU A  1 331 ? 180.098 198.454 174.745 1.00 46.44  ? 331 LEU B CG  1 
ATOM   857  C CD1 . LEU A  1 331 ? 179.067 198.906 173.733 1.00 56.12  ? 331 LEU B CD1 1 
ATOM   858  C CD2 . LEU A  1 331 ? 180.491 199.612 175.644 1.00 47.98  ? 331 LEU B CD2 1 
ATOM   859  N N   . LEU A  1 332 ? 179.975 194.320 174.450 1.00 59.14  ? 332 LEU B N   1 
ATOM   860  C CA  . LEU A  1 332 ? 180.674 193.367 173.595 1.00 56.90  ? 332 LEU B CA  1 
ATOM   861  C C   . LEU A  1 332 ? 179.717 192.706 172.613 1.00 54.49  ? 332 LEU B C   1 
ATOM   862  O O   . LEU A  1 332 ? 180.043 192.543 171.432 1.00 57.42  ? 332 LEU B O   1 
ATOM   863  C CB  . LEU A  1 332 ? 181.373 192.313 174.452 1.00 51.73  ? 332 LEU B CB  1 
ATOM   864  C CG  . LEU A  1 332 ? 182.771 192.658 174.963 1.00 48.94  ? 332 LEU B CG  1 
ATOM   865  C CD1 . LEU A  1 332 ? 183.465 191.410 175.464 1.00 50.74  ? 332 LEU B CD1 1 
ATOM   866  C CD2 . LEU A  1 332 ? 183.590 193.321 173.872 1.00 56.11  ? 332 LEU B CD2 1 
ATOM   867  N N   . ALA A  1 333 ? 178.531 192.318 173.085 1.00 43.84  ? 333 ALA B N   1 
ATOM   868  C CA  . ALA A  1 333 ? 177.539 191.731 172.191 1.00 53.78  ? 333 ALA B CA  1 
ATOM   869  C C   . ALA A  1 333 ? 177.092 192.733 171.135 1.00 62.11  ? 333 ALA B C   1 
ATOM   870  O O   . ALA A  1 333 ? 176.781 192.355 170.000 1.00 64.12  ? 333 ALA B O   1 
ATOM   871  C CB  . ALA A  1 333 ? 176.344 191.223 172.993 1.00 57.95  ? 333 ALA B CB  1 
ATOM   872  N N   . CYS A  1 334 ? 177.039 194.016 171.495 1.00 66.50  ? 334 CYS B N   1 
ATOM   873  C CA  . CYS A  1 334 ? 176.713 195.041 170.510 1.00 63.94  ? 334 CYS B CA  1 
ATOM   874  C C   . CYS A  1 334 ? 177.813 195.179 169.465 1.00 67.81  ? 334 CYS B C   1 
ATOM   875  O O   . CYS A  1 334 ? 177.526 195.375 168.278 1.00 70.68  ? 334 CYS B O   1 
ATOM   876  C CB  . CYS A  1 334 ? 176.463 196.377 171.204 1.00 58.38  ? 334 CYS B CB  1 
ATOM   877  S SG  . CYS A  1 334 ? 174.771 196.605 171.773 1.00 77.11  ? 334 CYS B SG  1 
ATOM   878  N N   . PHE A  1 335 ? 179.078 195.089 169.886 1.00 65.62  ? 335 PHE B N   1 
ATOM   879  C CA  . PHE A  1 335 ? 180.184 195.267 168.948 1.00 67.06  ? 335 PHE B CA  1 
ATOM   880  C C   . PHE A  1 335 ? 180.185 194.178 167.881 1.00 70.95  ? 335 PHE B C   1 
ATOM   881  O O   . PHE A  1 335 ? 180.220 194.470 166.680 1.00 67.06  ? 335 PHE B O   1 
ATOM   882  C CB  . PHE A  1 335 ? 181.512 195.288 169.703 1.00 64.25  ? 335 PHE B CB  1 
ATOM   883  C CG  . PHE A  1 335 ? 181.984 196.668 170.046 1.00 68.13  ? 335 PHE B CG  1 
ATOM   884  C CD1 . PHE A  1 335 ? 182.582 197.464 169.087 1.00 69.93  ? 335 PHE B CD1 1 
ATOM   885  C CD2 . PHE A  1 335 ? 181.821 197.172 171.322 1.00 71.35  ? 335 PHE B CD2 1 
ATOM   886  C CE1 . PHE A  1 335 ? 183.013 198.735 169.397 1.00 70.82  ? 335 PHE B CE1 1 
ATOM   887  C CE2 . PHE A  1 335 ? 182.249 198.443 171.637 1.00 71.24  ? 335 PHE B CE2 1 
ATOM   888  C CZ  . PHE A  1 335 ? 182.846 199.225 170.675 1.00 69.40  ? 335 PHE B CZ  1 
ATOM   889  N N   . PHE A  1 336 ? 180.148 192.915 168.300 1.00 75.20  ? 336 PHE B N   1 
ATOM   890  C CA  . PHE A  1 336 ? 179.967 191.791 167.389 1.00 72.02  ? 336 PHE B CA  1 
ATOM   891  C C   . PHE A  1 336 ? 178.817 190.940 167.902 1.00 69.63  ? 336 PHE B C   1 
ATOM   892  O O   . PHE A  1 336 ? 178.738 190.655 169.100 1.00 68.53  ? 336 PHE B O   1 
ATOM   893  C CB  . PHE A  1 336 ? 181.253 190.964 167.235 1.00 69.81  ? 336 PHE B CB  1 
ATOM   894  C CG  . PHE A  1 336 ? 182.083 190.855 168.490 1.00 69.83  ? 336 PHE B CG  1 
ATOM   895  C CD1 . PHE A  1 336 ? 181.577 190.275 169.639 1.00 67.02  ? 336 PHE B CD1 1 
ATOM   896  C CD2 . PHE A  1 336 ? 183.387 191.322 168.506 1.00 66.98  ? 336 PHE B CD2 1 
ATOM   897  C CE1 . PHE A  1 336 ? 182.346 190.175 170.780 1.00 69.56  ? 336 PHE B CE1 1 
ATOM   898  C CE2 . PHE A  1 336 ? 184.162 191.225 169.643 1.00 66.67  ? 336 PHE B CE2 1 
ATOM   899  C CZ  . PHE A  1 336 ? 183.641 190.650 170.782 1.00 70.07  ? 336 PHE B CZ  1 
ATOM   900  N N   . ALA A  1 337 ? 177.916 190.557 167.003 1.00 74.27  ? 337 ALA B N   1 
ATOM   901  C CA  . ALA A  1 337 ? 176.731 189.807 167.394 1.00 77.46  ? 337 ALA B CA  1 
ATOM   902  C C   . ALA A  1 337 ? 177.051 188.321 167.491 1.00 77.13  ? 337 ALA B C   1 
ATOM   903  O O   . ALA A  1 337 ? 177.214 187.654 166.461 1.00 77.21  ? 337 ALA B O   1 
ATOM   904  C CB  . ALA A  1 337 ? 175.593 190.045 166.400 1.00 76.91  ? 337 ALA B CB  1 
ATOM   905  N N   . PRO A  1 338 ? 177.159 187.770 168.703 1.00 78.89  ? 338 PRO B N   1 
ATOM   906  C CA  . PRO A  1 338 ? 177.427 186.327 168.817 1.00 79.19  ? 338 PRO B CA  1 
ATOM   907  C C   . PRO A  1 338 ? 176.321 185.475 168.226 1.00 78.18  ? 338 PRO B C   1 
ATOM   908  O O   . PRO A  1 338 ? 176.593 184.408 167.661 1.00 78.50  ? 338 PRO B O   1 
ATOM   909  C CB  . PRO A  1 338 ? 177.568 186.112 170.333 1.00 81.22  ? 338 PRO B CB  1 
ATOM   910  C CG  . PRO A  1 338 ? 177.617 187.488 170.942 1.00 81.91  ? 338 PRO B CG  1 
ATOM   911  C CD  . PRO A  1 338 ? 176.871 188.375 170.010 1.00 80.31  ? 338 PRO B CD  1 
ATOM   912  N N   . ILE A  1 339 ? 175.076 185.923 168.335 1.00 78.69  ? 339 ILE B N   1 
ATOM   913  C CA  . ILE A  1 339 ? 173.922 185.205 167.812 1.00 78.41  ? 339 ILE B CA  1 
ATOM   914  C C   . ILE A  1 339 ? 173.346 186.040 166.678 1.00 79.63  ? 339 ILE B C   1 
ATOM   915  O O   . ILE A  1 339 ? 172.842 187.147 166.903 1.00 78.21  ? 339 ILE B O   1 
ATOM   916  C CB  . ILE A  1 339 ? 172.869 184.941 168.897 1.00 77.13  ? 339 ILE B CB  1 
ATOM   917  C CG1 . ILE A  1 339 ? 173.522 184.364 170.157 1.00 78.02  ? 339 ILE B CG1 1 
ATOM   918  C CG2 . ILE A  1 339 ? 171.791 184.005 168.374 1.00 76.29  ? 339 ILE B CG2 1 
ATOM   919  C CD1 . ILE A  1 339 ? 173.780 185.387 171.246 1.00 77.19  ? 339 ILE B CD1 1 
ATOM   920  N N   . SER A  1 340 ? 173.421 185.514 165.455 1.00 84.18  ? 340 SER B N   1 
ATOM   921  C CA  . SER A  1 340 ? 172.873 186.226 164.307 1.00 85.95  ? 340 SER B CA  1 
ATOM   922  C C   . SER A  1 340 ? 171.356 186.336 164.368 1.00 83.63  ? 340 SER B C   1 
ATOM   923  O O   . SER A  1 340 ? 170.788 187.241 163.748 1.00 79.81  ? 340 SER B O   1 
ATOM   924  C CB  . SER A  1 340 ? 173.294 185.535 163.009 1.00 87.25  ? 340 SER B CB  1 
ATOM   925  O OG  . SER A  1 340 ? 174.705 185.476 162.898 1.00 87.76  ? 340 SER B OG  1 
ATOM   926  N N   . VAL A  1 341 ? 170.691 185.437 165.096 1.00 81.73  ? 341 VAL B N   1 
ATOM   927  C CA  . VAL A  1 341 ? 169.239 185.505 165.211 1.00 78.56  ? 341 VAL B CA  1 
ATOM   928  C C   . VAL A  1 341 ? 168.823 186.702 166.055 1.00 78.93  ? 341 VAL B C   1 
ATOM   929  O O   . VAL A  1 341 ? 167.851 187.396 165.735 1.00 81.81  ? 341 VAL B O   1 
ATOM   930  C CB  . VAL A  1 341 ? 168.688 184.189 165.787 1.00 81.30  ? 341 VAL B CB  1 
ATOM   931  C CG1 . VAL A  1 341 ? 167.218 184.034 165.436 1.00 79.59  ? 341 VAL B CG1 1 
ATOM   932  C CG2 . VAL A  1 341 ? 169.495 183.008 165.275 1.00 81.22  ? 341 VAL B CG2 1 
ATOM   933  N N   . ILE A  1 342 ? 169.543 186.963 167.142 1.00 76.63  ? 342 ILE B N   1 
ATOM   934  C CA  . ILE A  1 342 ? 169.202 188.050 168.057 1.00 78.53  ? 342 ILE B CA  1 
ATOM   935  C C   . ILE A  1 342 ? 169.655 189.377 167.460 1.00 79.05  ? 342 ILE B C   1 
ATOM   936  O O   . ILE A  1 342 ? 170.851 189.556 167.186 1.00 79.58  ? 342 ILE B O   1 
ATOM   937  C CB  . ILE A  1 342 ? 169.827 187.829 169.443 1.00 74.35  ? 342 ILE B CB  1 
ATOM   938  C CG1 . ILE A  1 342 ? 169.135 186.670 170.163 1.00 76.89  ? 342 ILE B CG1 1 
ATOM   939  C CG2 . ILE A  1 342 ? 169.746 189.101 170.272 1.00 75.07  ? 342 ILE B CG2 1 
ATOM   940  C CD1 . ILE A  1 342 ? 167.779 187.025 170.739 1.00 75.00  ? 342 ILE B CD1 1 
ATOM   941  N N   . PRO A  1 343 ? 168.747 190.325 167.242 1.00 71.26  ? 343 PRO B N   1 
ATOM   942  C CA  . PRO A  1 343 ? 169.158 191.632 166.720 1.00 71.23  ? 343 PRO B CA  1 
ATOM   943  C C   . PRO A  1 343 ? 170.029 192.380 167.716 1.00 76.30  ? 343 PRO B C   1 
ATOM   944  O O   . PRO A  1 343 ? 169.898 192.226 168.933 1.00 78.85  ? 343 PRO B O   1 
ATOM   945  C CB  . PRO A  1 343 ? 167.829 192.360 166.483 1.00 72.71  ? 343 PRO B CB  1 
ATOM   946  C CG  . PRO A  1 343 ? 166.775 191.297 166.524 1.00 72.53  ? 343 PRO B CG  1 
ATOM   947  C CD  . PRO A  1 343 ? 167.292 190.236 167.435 1.00 72.63  ? 343 PRO B CD  1 
ATOM   948  N N   . THR A  1 344 ? 170.927 193.208 167.178 1.00 77.69  ? 344 THR B N   1 
ATOM   949  C CA  . THR A  1 344 ? 171.924 193.875 168.006 1.00 79.28  ? 344 THR B CA  1 
ATOM   950  C C   . THR A  1 344 ? 171.335 194.966 168.889 1.00 76.98  ? 344 THR B C   1 
ATOM   951  O O   . THR A  1 344 ? 171.989 195.381 169.851 1.00 76.44  ? 344 THR B O   1 
ATOM   952  C CB  . THR A  1 344 ? 173.027 194.465 167.127 1.00 81.91  ? 344 THR B CB  1 
ATOM   953  O OG1 . THR A  1 344 ? 173.856 195.330 167.913 1.00 80.78  ? 344 THR B OG1 1 
ATOM   954  C CG2 . THR A  1 344 ? 172.424 195.247 165.978 1.00 79.54  ? 344 THR B CG2 1 
ATOM   955  N N   . TYR A  1 345 ? 170.126 195.443 168.596 1.00 79.05  ? 345 TYR B N   1 
ATOM   956  C CA  . TYR A  1 345 ? 169.508 196.462 169.434 1.00 83.15  ? 345 TYR B CA  1 
ATOM   957  C C   . TYR A  1 345 ? 168.843 195.884 170.676 1.00 78.64  ? 345 TYR B C   1 
ATOM   958  O O   . TYR A  1 345 ? 168.342 196.651 171.504 1.00 77.93  ? 345 TYR B O   1 
ATOM   959  C CB  . TYR A  1 345 ? 168.485 197.272 168.631 1.00 83.73  ? 345 TYR B CB  1 
ATOM   960  C CG  . TYR A  1 345 ? 167.463 196.446 167.881 1.00 82.04  ? 345 TYR B CG  1 
ATOM   961  C CD1 . TYR A  1 345 ? 166.421 195.817 168.549 1.00 78.53  ? 345 TYR B CD1 1 
ATOM   962  C CD2 . TYR A  1 345 ? 167.527 196.317 166.501 1.00 82.13  ? 345 TYR B CD2 1 
ATOM   963  C CE1 . TYR A  1 345 ? 165.487 195.068 167.866 1.00 80.86  ? 345 TYR B CE1 1 
ATOM   964  C CE2 . TYR A  1 345 ? 166.593 195.573 165.809 1.00 82.14  ? 345 TYR B CE2 1 
ATOM   965  C CZ  . TYR A  1 345 ? 165.575 194.951 166.497 1.00 83.68  ? 345 TYR B CZ  1 
ATOM   966  O OH  . TYR A  1 345 ? 164.643 194.207 165.812 1.00 83.70  ? 345 TYR B OH  1 
ATOM   967  N N   . VAL A  1 346 ? 168.818 194.560 170.820 1.00 66.45  ? 346 VAL B N   1 
ATOM   968  C CA  . VAL A  1 346 ? 168.228 193.955 172.007 1.00 67.28  ? 346 VAL B CA  1 
ATOM   969  C C   . VAL A  1 346 ? 169.186 194.033 173.191 1.00 68.36  ? 346 VAL B C   1 
ATOM   970  O O   . VAL A  1 346 ? 168.747 194.152 174.342 1.00 70.22  ? 346 VAL B O   1 
ATOM   971  C CB  . VAL A  1 346 ? 167.814 192.505 171.699 1.00 65.06  ? 346 VAL B CB  1 
ATOM   972  C CG1 . VAL A  1 346 ? 167.488 191.742 172.975 1.00 61.39  ? 346 VAL B CG1 1 
ATOM   973  C CG2 . VAL A  1 346 ? 166.631 192.487 170.747 1.00 70.07  ? 346 VAL B CG2 1 
ATOM   974  N N   . TYR A  1 347 ? 170.494 193.996 172.933 1.00 58.79  ? 347 TYR B N   1 
ATOM   975  C CA  . TYR A  1 347 ? 171.468 193.908 174.021 1.00 59.88  ? 347 TYR B CA  1 
ATOM   976  C C   . TYR A  1 347 ? 171.406 195.082 174.990 1.00 65.98  ? 347 TYR B C   1 
ATOM   977  O O   . TYR A  1 347 ? 171.376 194.838 176.209 1.00 69.57  ? 347 TYR B O   1 
ATOM   978  C CB  . TYR A  1 347 ? 172.871 193.738 173.433 1.00 54.35  ? 347 TYR B CB  1 
ATOM   979  C CG  . TYR A  1 347 ? 173.003 192.533 172.533 1.00 62.31  ? 347 TYR B CG  1 
ATOM   980  C CD1 . TYR A  1 347 ? 172.760 191.255 173.014 1.00 63.12  ? 347 TYR B CD1 1 
ATOM   981  C CD2 . TYR A  1 347 ? 173.365 192.674 171.202 1.00 63.56  ? 347 TYR B CD2 1 
ATOM   982  C CE1 . TYR A  1 347 ? 172.876 190.151 172.196 1.00 60.05  ? 347 TYR B CE1 1 
ATOM   983  C CE2 . TYR A  1 347 ? 173.484 191.576 170.376 1.00 65.45  ? 347 TYR B CE2 1 
ATOM   984  C CZ  . TYR A  1 347 ? 173.239 190.317 170.878 1.00 64.44  ? 347 TYR B CZ  1 
ATOM   985  O OH  . TYR A  1 347 ? 173.357 189.222 170.056 1.00 66.23  ? 347 TYR B OH  1 
ATOM   986  N N   . PRO A  1 348 ? 171.400 196.349 174.556 1.00 57.84  ? 348 PRO B N   1 
ATOM   987  C CA  . PRO A  1 348 ? 171.259 197.431 175.544 1.00 44.96  ? 348 PRO B CA  1 
ATOM   988  C C   . PRO A  1 348 ? 169.909 197.430 176.235 1.00 52.14  ? 348 PRO B C   1 
ATOM   989  O O   . PRO A  1 348 ? 169.829 197.716 177.438 1.00 67.46  ? 348 PRO B O   1 
ATOM   990  C CB  . PRO A  1 348 ? 171.484 198.684 174.689 1.00 44.44  ? 348 PRO B CB  1 
ATOM   991  C CG  . PRO A  1 348 ? 170.920 198.279 173.385 1.00 52.43  ? 348 PRO B CG  1 
ATOM   992  C CD  . PRO A  1 348 ? 171.535 196.918 173.205 1.00 62.72  ? 348 PRO B CD  1 
ATOM   993  N N   . LEU A  1 349 ? 168.841 197.102 175.505 1.00 51.50  ? 349 LEU B N   1 
ATOM   994  C CA  . LEU A  1 349 ? 167.539 196.951 176.141 1.00 54.00  ? 349 LEU B CA  1 
ATOM   995  C C   . LEU A  1 349 ? 167.561 195.824 177.161 1.00 52.35  ? 349 LEU B C   1 
ATOM   996  O O   . LEU A  1 349 ? 166.993 195.956 178.249 1.00 51.97  ? 349 LEU B O   1 
ATOM   997  C CB  . LEU A  1 349 ? 166.457 196.704 175.093 1.00 46.85  ? 349 LEU B CB  1 
ATOM   998  C CG  . LEU A  1 349 ? 165.044 197.018 175.582 1.00 49.97  ? 349 LEU B CG  1 
ATOM   999  C CD1 . LEU A  1 349 ? 164.734 198.493 175.440 1.00 54.98  ? 349 LEU B CD1 1 
ATOM   1000 C CD2 . LEU A  1 349 ? 164.022 196.180 174.833 1.00 55.47  ? 349 LEU B CD2 1 
ATOM   1001 N N   . ALA A  1 350 ? 168.220 194.713 176.832 1.00 53.34  ? 350 ALA B N   1 
ATOM   1002 C CA  . ALA A  1 350 ? 168.347 193.618 177.788 1.00 55.24  ? 350 ALA B CA  1 
ATOM   1003 C C   . ALA A  1 350 ? 169.106 194.064 179.031 1.00 59.60  ? 350 ALA B C   1 
ATOM   1004 O O   . ALA A  1 350 ? 168.708 193.755 180.159 1.00 63.07  ? 350 ALA B O   1 
ATOM   1005 C CB  . ALA A  1 350 ? 169.039 192.426 177.130 1.00 56.54  ? 350 ALA B CB  1 
ATOM   1006 N N   . LEU A  1 351 ? 170.196 194.811 178.843 1.00 58.78  ? 351 LEU B N   1 
ATOM   1007 C CA  . LEU A  1 351 ? 170.999 195.261 179.975 1.00 53.21  ? 351 LEU B CA  1 
ATOM   1008 C C   . LEU A  1 351 ? 170.197 196.176 180.891 1.00 51.15  ? 351 LEU B C   1 
ATOM   1009 O O   . LEU A  1 351 ? 170.172 195.985 182.113 1.00 60.83  ? 351 LEU B O   1 
ATOM   1010 C CB  . LEU A  1 351 ? 172.256 195.973 179.476 1.00 47.90  ? 351 LEU B CB  1 
ATOM   1011 C CG  . LEU A  1 351 ? 172.939 196.909 180.474 1.00 43.06  ? 351 LEU B CG  1 
ATOM   1012 C CD1 . LEU A  1 351 ? 173.573 196.122 181.605 1.00 47.97  ? 351 LEU B CD1 1 
ATOM   1013 C CD2 . LEU A  1 351 ? 173.970 197.780 179.778 1.00 46.17  ? 351 LEU B CD2 1 
ATOM   1014 N N   . TYR A  1 352 ? 169.528 197.175 180.319 1.00 42.10  ? 352 TYR B N   1 
ATOM   1015 C CA  . TYR A  1 352 ? 168.793 198.115 181.157 1.00 44.86  ? 352 TYR B CA  1 
ATOM   1016 C C   . TYR A  1 352 ? 167.542 197.489 181.760 1.00 54.13  ? 352 TYR B C   1 
ATOM   1017 O O   . TYR A  1 352 ? 167.179 197.818 182.896 1.00 67.64  ? 352 TYR B O   1 
ATOM   1018 C CB  . TYR A  1 352 ? 168.454 199.373 180.362 1.00 45.54  ? 352 TYR B CB  1 
ATOM   1019 C CG  . TYR A  1 352 ? 169.686 200.166 179.997 1.00 49.34  ? 352 TYR B CG  1 
ATOM   1020 C CD1 . TYR A  1 352 ? 170.566 200.599 180.977 1.00 50.31  ? 352 TYR B CD1 1 
ATOM   1021 C CD2 . TYR A  1 352 ? 169.977 200.468 178.677 1.00 54.96  ? 352 TYR B CD2 1 
ATOM   1022 C CE1 . TYR A  1 352 ? 171.696 201.316 180.653 1.00 48.49  ? 352 TYR B CE1 1 
ATOM   1023 C CE2 . TYR A  1 352 ? 171.105 201.187 178.344 1.00 58.65  ? 352 TYR B CE2 1 
ATOM   1024 C CZ  . TYR A  1 352 ? 171.960 201.608 179.334 1.00 54.83  ? 352 TYR B CZ  1 
ATOM   1025 O OH  . TYR A  1 352 ? 173.084 202.325 179.001 1.00 59.06  ? 352 TYR B OH  1 
ATOM   1026 N N   . GLY A  1 353 ? 166.888 196.574 181.043 1.00 53.14  ? 353 GLY B N   1 
ATOM   1027 C CA  . GLY A  1 353 ? 165.790 195.838 181.638 1.00 58.62  ? 353 GLY B CA  1 
ATOM   1028 C C   . GLY A  1 353 ? 166.239 194.980 182.803 1.00 62.36  ? 353 GLY B C   1 
ATOM   1029 O O   . GLY A  1 353 ? 165.551 194.900 183.823 1.00 59.69  ? 353 GLY B O   1 
ATOM   1030 N N   . PHE A  1 354 ? 167.399 194.329 182.673 1.00 68.97  ? 354 PHE B N   1 
ATOM   1031 C CA  . PHE A  1 354 ? 167.911 193.546 183.789 1.00 63.79  ? 354 PHE B CA  1 
ATOM   1032 C C   . PHE A  1 354 ? 168.252 194.459 184.956 1.00 63.42  ? 354 PHE B C   1 
ATOM   1033 O O   . PHE A  1 354 ? 168.012 194.103 186.110 1.00 65.49  ? 354 PHE B O   1 
ATOM   1034 C CB  . PHE A  1 354 ? 169.123 192.710 183.353 1.00 59.98  ? 354 PHE B CB  1 
ATOM   1035 C CG  . PHE A  1 354 ? 169.799 191.937 184.479 1.00 65.51  ? 354 PHE B CG  1 
ATOM   1036 C CD1 . PHE A  1 354 ? 170.434 192.572 185.539 1.00 65.45  ? 354 PHE B CD1 1 
ATOM   1037 C CD2 . PHE A  1 354 ? 169.772 190.553 184.473 1.00 69.24  ? 354 PHE B CD2 1 
ATOM   1038 C CE1 . PHE A  1 354 ? 171.016 191.848 186.559 1.00 67.96  ? 354 PHE B CE1 1 
ATOM   1039 C CE2 . PHE A  1 354 ? 170.365 189.825 185.487 1.00 68.69  ? 354 PHE B CE2 1 
ATOM   1040 C CZ  . PHE A  1 354 ? 170.990 190.474 186.528 1.00 69.19  ? 354 PHE B CZ  1 
ATOM   1041 N N   . MET A  1 355 ? 168.830 195.629 184.680 1.00 63.71  ? 355 MET B N   1 
ATOM   1042 C CA  . MET A  1 355 ? 169.145 196.561 185.759 1.00 56.83  ? 355 MET B CA  1 
ATOM   1043 C C   . MET A  1 355 ? 167.881 196.981 186.500 1.00 62.23  ? 355 MET B C   1 
ATOM   1044 O O   . MET A  1 355 ? 167.845 196.996 187.737 1.00 67.87  ? 355 MET B O   1 
ATOM   1045 C CB  . MET A  1 355 ? 169.877 197.783 185.204 1.00 52.66  ? 355 MET B CB  1 
ATOM   1046 C CG  . MET A  1 355 ? 171.359 197.822 185.525 1.00 58.59  ? 355 MET B CG  1 
ATOM   1047 S SD  . MET A  1 355 ? 172.205 199.178 184.692 1.00 83.77  ? 355 MET B SD  1 
ATOM   1048 C CE  . MET A  1 355 ? 173.891 198.580 184.695 1.00 55.92  ? 355 MET B CE  1 
ATOM   1049 N N   . VAL A  1 356 ? 166.823 197.303 185.754 1.00 59.22  ? 356 VAL B N   1 
ATOM   1050 C CA  . VAL A  1 356 ? 165.567 197.700 186.383 1.00 59.08  ? 356 VAL B CA  1 
ATOM   1051 C C   . VAL A  1 356 ? 164.986 196.547 187.192 1.00 64.63  ? 356 VAL B C   1 
ATOM   1052 O O   . VAL A  1 356 ? 164.565 196.728 188.341 1.00 64.86  ? 356 VAL B O   1 
ATOM   1053 C CB  . VAL A  1 356 ? 164.575 198.210 185.321 1.00 64.32  ? 356 VAL B CB  1 
ATOM   1054 C CG1 . VAL A  1 356 ? 163.140 197.988 185.774 1.00 66.53  ? 356 VAL B CG1 1 
ATOM   1055 C CG2 . VAL A  1 356 ? 164.824 199.681 185.032 1.00 62.10  ? 356 VAL B CG2 1 
ATOM   1056 N N   . PHE A  1 357 ? 164.974 195.340 186.618 1.00 73.01  ? 357 PHE B N   1 
ATOM   1057 C CA  . PHE A  1 357 ? 164.418 194.183 187.316 1.00 75.81  ? 357 PHE B CA  1 
ATOM   1058 C C   . PHE A  1 357 ? 165.220 193.853 188.567 1.00 73.25  ? 357 PHE B C   1 
ATOM   1059 O O   . PHE A  1 357 ? 164.652 193.482 189.601 1.00 68.49  ? 357 PHE B O   1 
ATOM   1060 C CB  . PHE A  1 357 ? 164.372 192.979 186.375 1.00 72.37  ? 357 PHE B CB  1 
ATOM   1061 C CG  . PHE A  1 357 ? 164.037 191.686 187.061 1.00 77.68  ? 357 PHE B CG  1 
ATOM   1062 C CD1 . PHE A  1 357 ? 162.769 191.466 187.573 1.00 78.64  ? 357 PHE B CD1 1 
ATOM   1063 C CD2 . PHE A  1 357 ? 164.990 190.689 187.190 1.00 75.39  ? 357 PHE B CD2 1 
ATOM   1064 C CE1 . PHE A  1 357 ? 162.459 190.276 188.204 1.00 78.30  ? 357 PHE B CE1 1 
ATOM   1065 C CE2 . PHE A  1 357 ? 164.686 189.497 187.820 1.00 75.01  ? 357 PHE B CE2 1 
ATOM   1066 C CZ  . PHE A  1 357 ? 163.419 189.290 188.328 1.00 75.82  ? 357 PHE B CZ  1 
ATOM   1067 N N   . PHE A  1 358 ? 166.545 193.972 188.486 1.00 66.35  ? 358 PHE B N   1 
ATOM   1068 C CA  . PHE A  1 358 ? 167.395 193.769 189.649 1.00 61.47  ? 358 PHE B CA  1 
ATOM   1069 C C   . PHE A  1 358 ? 167.098 194.804 190.719 1.00 59.15  ? 358 PHE B C   1 
ATOM   1070 O O   . PHE A  1 358 ? 167.140 194.496 191.911 1.00 59.37  ? 358 PHE B O   1 
ATOM   1071 C CB  . PHE A  1 358 ? 168.867 193.825 189.230 1.00 60.28  ? 358 PHE B CB  1 
ATOM   1072 C CG  . PHE A  1 358 ? 169.836 193.821 190.381 1.00 62.58  ? 358 PHE B CG  1 
ATOM   1073 C CD1 . PHE A  1 358 ? 170.272 195.009 190.944 1.00 62.36  ? 358 PHE B CD1 1 
ATOM   1074 C CD2 . PHE A  1 358 ? 170.325 192.630 190.886 1.00 68.56  ? 358 PHE B CD2 1 
ATOM   1075 C CE1 . PHE A  1 358 ? 171.165 195.007 191.996 1.00 63.90  ? 358 PHE B CE1 1 
ATOM   1076 C CE2 . PHE A  1 358 ? 171.220 192.623 191.938 1.00 65.52  ? 358 PHE B CE2 1 
ATOM   1077 C CZ  . PHE A  1 358 ? 171.640 193.813 192.493 1.00 62.16  ? 358 PHE B CZ  1 
ATOM   1078 N N   . LEU A  1 359 ? 166.807 196.041 190.312 1.00 62.45  ? 359 LEU B N   1 
ATOM   1079 C CA  . LEU A  1 359 ? 166.463 197.067 191.291 1.00 65.14  ? 359 LEU B CA  1 
ATOM   1080 C C   . LEU A  1 359 ? 165.085 196.822 191.897 1.00 65.30  ? 359 LEU B C   1 
ATOM   1081 O O   . LEU A  1 359 ? 164.876 197.067 193.090 1.00 60.98  ? 359 LEU B O   1 
ATOM   1082 C CB  . LEU A  1 359 ? 166.528 198.451 190.648 1.00 60.53  ? 359 LEU B CB  1 
ATOM   1083 C CG  . LEU A  1 359 ? 166.344 199.623 191.612 1.00 58.01  ? 359 LEU B CG  1 
ATOM   1084 C CD1 . LEU A  1 359 ? 167.366 199.549 192.731 1.00 61.87  ? 359 LEU B CD1 1 
ATOM   1085 C CD2 . LEU A  1 359 ? 166.439 200.951 190.882 1.00 60.90  ? 359 LEU B CD2 1 
ATOM   1086 N N   . ILE A  1 360 ? 164.133 196.340 191.099 1.00 63.35  ? 360 ILE B N   1 
ATOM   1087 C CA  . ILE A  1 360 ? 162.759 196.164 191.556 1.00 58.07  ? 360 ILE B CA  1 
ATOM   1088 C C   . ILE A  1 360 ? 162.465 194.704 191.908 1.00 66.22  ? 360 ILE B C   1 
ATOM   1089 O O   . ILE A  1 360 ? 161.299 194.309 192.006 1.00 69.23  ? 360 ILE B O   1 
ATOM   1090 C CB  . ILE A  1 360 ? 161.770 196.711 190.507 1.00 62.83  ? 360 ILE B CB  1 
ATOM   1091 C CG1 . ILE A  1 360 ? 160.364 196.898 191.090 1.00 67.02  ? 360 ILE B CG1 1 
ATOM   1092 C CG2 . ILE A  1 360 ? 161.712 195.800 189.289 1.00 64.69  ? 360 ILE B CG2 1 
ATOM   1093 C CD1 . ILE A  1 360 ? 159.552 197.969 190.397 1.00 64.45  ? 360 ILE B CD1 1 
ATOM   1094 N N   . ASN A  1 361 ? 163.498 193.899 192.123 1.00 74.77  ? 361 ASN B N   1 
ATOM   1095 C CA  . ASN A  1 361 ? 163.317 192.486 192.430 1.00 71.11  ? 361 ASN B CA  1 
ATOM   1096 C C   . ASN A  1 361 ? 162.570 192.329 193.750 1.00 75.96  ? 361 ASN B C   1 
ATOM   1097 O O   . ASN A  1 361 ? 163.042 192.826 194.784 1.00 75.52  ? 361 ASN B O   1 
ATOM   1098 C CB  . ASN A  1 361 ? 164.676 191.790 192.498 1.00 68.62  ? 361 ASN B CB  1 
ATOM   1099 C CG  . ASN A  1 361 ? 164.567 190.276 192.506 1.00 75.05  ? 361 ASN B CG  1 
ATOM   1100 O OD1 . ASN A  1 361 ? 163.601 189.708 193.014 1.00 76.21  ? 361 ASN B OD1 1 
ATOM   1101 N ND2 . ASN A  1 361 ? 165.567 189.612 191.938 1.00 76.59  ? 361 ASN B ND2 1 
ATOM   1102 N N   . PRO A  1 362 ? 161.415 191.657 193.767 1.00 76.42  ? 362 PRO B N   1 
ATOM   1103 C CA  . PRO A  1 362 ? 160.661 191.514 195.019 1.00 74.54  ? 362 PRO B CA  1 
ATOM   1104 C C   . PRO A  1 362 ? 161.199 190.416 195.923 1.00 78.28  ? 362 PRO B C   1 
ATOM   1105 O O   . PRO A  1 362 ? 161.129 190.529 197.151 1.00 75.83  ? 362 PRO B O   1 
ATOM   1106 C CB  . PRO A  1 362 ? 159.244 191.195 194.531 1.00 73.04  ? 362 PRO B CB  1 
ATOM   1107 C CG  . PRO A  1 362 ? 159.458 190.486 193.239 1.00 73.97  ? 362 PRO B CG  1 
ATOM   1108 C CD  . PRO A  1 362 ? 160.692 191.090 192.615 1.00 72.99  ? 362 PRO B CD  1 
ATOM   1109 N N   . THR A  1 363 ? 161.731 189.350 195.328 1.00 74.98  ? 363 THR B N   1 
ATOM   1110 C CA  . THR A  1 363 ? 162.220 188.220 196.107 1.00 70.81  ? 363 THR B CA  1 
ATOM   1111 C C   . THR A  1 363 ? 163.430 188.629 196.935 1.00 71.90  ? 363 THR B C   1 
ATOM   1112 O O   . THR A  1 363 ? 164.379 189.224 196.417 1.00 77.65  ? 363 THR B O   1 
ATOM   1113 C CB  . THR A  1 363 ? 162.582 187.059 195.185 1.00 73.23  ? 363 THR B CB  1 
ATOM   1114 O OG1 . THR A  1 363 ? 163.598 187.479 194.266 1.00 80.20  ? 363 THR B OG1 1 
ATOM   1115 C CG2 . THR A  1 363 ? 161.361 186.600 194.407 1.00 74.11  ? 363 THR B CG2 1 
ATOM   1116 N N   . LYS A  1 364 ? 163.403 188.293 198.225 1.00 69.59  ? 364 LYS B N   1 
ATOM   1117 C CA  . LYS A  1 364 ? 164.446 188.710 199.162 1.00 74.84  ? 364 LYS B CA  1 
ATOM   1118 C C   . LYS A  1 364 ? 165.697 187.857 198.949 1.00 67.60  ? 364 LYS B C   1 
ATOM   1119 O O   . LYS A  1 364 ? 166.080 187.025 199.773 1.00 72.84  ? 364 LYS B O   1 
ATOM   1120 C CB  . LYS A  1 364 ? 163.948 188.611 200.598 1.00 75.44  ? 364 LYS B CB  1 
ATOM   1121 C CG  . LYS A  1 364 ? 162.819 189.569 200.953 1.00 72.14  ? 364 LYS B CG  1 
ATOM   1122 C CD  . LYS A  1 364 ? 161.455 188.949 200.687 1.00 72.84  ? 364 LYS B CD  1 
ATOM   1123 C CE  . LYS A  1 364 ? 160.331 189.868 201.135 1.00 73.58  ? 364 LYS B CE  1 
ATOM   1124 N NZ  . LYS A  1 364 ? 158.992 189.265 200.885 1.00 69.35  ? 364 LYS B NZ  1 
ATOM   1125 N N   . THR A  1 365 ? 166.346 188.083 197.808 1.00 63.82  ? 365 THR B N   1 
ATOM   1126 C CA  . THR A  1 365 ? 167.511 187.300 197.417 1.00 74.84  ? 365 THR B CA  1 
ATOM   1127 C C   . THR A  1 365 ? 168.788 188.128 197.362 1.00 76.50  ? 365 THR B C   1 
ATOM   1128 O O   . THR A  1 365 ? 169.769 187.793 198.030 1.00 75.44  ? 365 THR B O   1 
ATOM   1129 C CB  . THR A  1 365 ? 167.255 186.633 196.060 1.00 78.53  ? 365 THR B CB  1 
ATOM   1130 O OG1 . THR A  1 365 ? 166.805 187.616 195.121 1.00 73.16  ? 365 THR B OG1 1 
ATOM   1131 C CG2 . THR A  1 365 ? 166.203 185.546 196.195 1.00 75.28  ? 365 THR B CG2 1 
ATOM   1132 N N   . PHE A  1 366 ? 168.806 189.207 196.582 1.00 75.58  ? 366 PHE B N   1 
ATOM   1133 C CA  . PHE A  1 366 ? 170.020 189.986 196.333 1.00 72.70  ? 366 PHE B CA  1 
ATOM   1134 C C   . PHE A  1 366 ? 169.880 191.362 196.978 1.00 72.52  ? 366 PHE B C   1 
ATOM   1135 O O   . PHE A  1 366 ? 169.202 192.240 196.437 1.00 71.14  ? 366 PHE B O   1 
ATOM   1136 C CB  . PHE A  1 366 ? 170.293 190.110 194.834 1.00 65.24  ? 366 PHE B CB  1 
ATOM   1137 C CG  . PHE A  1 366 ? 170.791 188.842 194.191 1.00 67.77  ? 366 PHE B CG  1 
ATOM   1138 C CD1 . PHE A  1 366 ? 170.865 187.658 194.904 1.00 66.25  ? 366 PHE B CD1 1 
ATOM   1139 C CD2 . PHE A  1 366 ? 171.185 188.840 192.863 1.00 72.71  ? 366 PHE B CD2 1 
ATOM   1140 C CE1 . PHE A  1 366 ? 171.322 186.499 194.308 1.00 70.42  ? 366 PHE B CE1 1 
ATOM   1141 C CE2 . PHE A  1 366 ? 171.642 187.683 192.261 1.00 67.34  ? 366 PHE B CE2 1 
ATOM   1142 C CZ  . PHE A  1 366 ? 171.711 186.512 192.984 1.00 68.84  ? 366 PHE B CZ  1 
ATOM   1143 N N   . TYR A  1 367 ? 170.537 191.546 198.126 1.00 66.72  ? 367 TYR B N   1 
ATOM   1144 C CA  . TYR A  1 367 ? 170.604 192.841 198.806 1.00 62.65  ? 367 TYR B CA  1 
ATOM   1145 C C   . TYR A  1 367 ? 169.211 193.409 199.069 1.00 65.35  ? 367 TYR B C   1 
ATOM   1146 O O   . TYR A  1 367 ? 168.946 194.589 198.838 1.00 73.33  ? 367 TYR B O   1 
ATOM   1147 C CB  . TYR A  1 367 ? 171.447 193.831 198.001 1.00 62.36  ? 367 TYR B CB  1 
ATOM   1148 C CG  . TYR A  1 367 ? 172.919 193.512 197.983 1.00 66.70  ? 367 TYR B CG  1 
ATOM   1149 C CD1 . TYR A  1 367 ? 173.711 193.750 199.095 1.00 71.92  ? 367 TYR B CD1 1 
ATOM   1150 C CD2 . TYR A  1 367 ? 173.518 192.975 196.852 1.00 64.06  ? 367 TYR B CD2 1 
ATOM   1151 C CE1 . TYR A  1 367 ? 175.056 193.461 199.085 1.00 71.06  ? 367 TYR B CE1 1 
ATOM   1152 C CE2 . TYR A  1 367 ? 174.865 192.683 196.832 1.00 63.72  ? 367 TYR B CE2 1 
ATOM   1153 C CZ  . TYR A  1 367 ? 175.629 192.929 197.952 1.00 69.77  ? 367 TYR B CZ  1 
ATOM   1154 O OH  . TYR A  1 367 ? 176.972 192.641 197.943 1.00 74.41  ? 367 TYR B OH  1 
ATOM   1155 N N   . TYR A  1 368 ? 168.316 192.556 199.570 1.00 66.41  ? 368 TYR B N   1 
ATOM   1156 C CA  . TYR A  1 368 ? 166.908 192.935 199.648 1.00 64.07  ? 368 TYR B CA  1 
ATOM   1157 C C   . TYR A  1 368 ? 166.689 194.125 200.576 1.00 65.05  ? 368 TYR B C   1 
ATOM   1158 O O   . TYR A  1 368 ? 165.915 195.031 200.253 1.00 73.16  ? 368 TYR B O   1 
ATOM   1159 C CB  . TYR A  1 368 ? 166.063 191.736 200.078 1.00 71.57  ? 368 TYR B CB  1 
ATOM   1160 C CG  . TYR A  1 368 ? 166.225 191.309 201.519 1.00 74.98  ? 368 TYR B CG  1 
ATOM   1161 C CD1 . TYR A  1 368 ? 167.293 190.515 201.911 1.00 71.38  ? 368 TYR B CD1 1 
ATOM   1162 C CD2 . TYR A  1 368 ? 165.297 191.679 202.481 1.00 72.36  ? 368 TYR B CD2 1 
ATOM   1163 C CE1 . TYR A  1 368 ? 167.441 190.115 203.223 1.00 72.40  ? 368 TYR B CE1 1 
ATOM   1164 C CE2 . TYR A  1 368 ? 165.435 191.281 203.795 1.00 71.93  ? 368 TYR B CE2 1 
ATOM   1165 C CZ  . TYR A  1 368 ? 166.510 190.501 204.161 1.00 72.33  ? 368 TYR B CZ  1 
ATOM   1166 O OH  . TYR A  1 368 ? 166.653 190.104 205.471 1.00 69.56  ? 368 TYR B OH  1 
ATOM   1167 N N   . LYS A  1 369 ? 167.366 194.153 201.725 1.00 62.34  ? 369 LYS B N   1 
ATOM   1168 C CA  . LYS A  1 369 ? 167.174 195.262 202.656 1.00 69.34  ? 369 LYS B CA  1 
ATOM   1169 C C   . LYS A  1 369 ? 167.612 196.582 202.033 1.00 68.83  ? 369 LYS B C   1 
ATOM   1170 O O   . LYS A  1 369 ? 166.844 197.554 201.996 1.00 66.39  ? 369 LYS B O   1 
ATOM   1171 C CB  . LYS A  1 369 ? 167.942 194.996 203.950 1.00 69.11  ? 369 LYS B CB  1 
ATOM   1172 C CG  . LYS A  1 369 ? 167.257 194.021 204.888 1.00 71.65  ? 369 LYS B CG  1 
ATOM   1173 C CD  . LYS A  1 369 ? 167.854 194.076 206.283 1.00 71.72  ? 369 LYS B CD  1 
ATOM   1174 C CE  . LYS A  1 369 ? 166.953 193.391 207.295 1.00 71.13  ? 369 LYS B CE  1 
ATOM   1175 N NZ  . LYS A  1 369 ? 167.330 193.731 208.693 1.00 73.08  ? 369 LYS B NZ  1 
ATOM   1176 N N   . SER A  1 370 ? 168.843 196.626 201.520 1.00 68.46  ? 370 SER B N   1 
ATOM   1177 C CA  . SER A  1 370 ? 169.361 197.851 200.920 1.00 61.63  ? 370 SER B CA  1 
ATOM   1178 C C   . SER A  1 370 ? 168.583 198.224 199.668 1.00 60.15  ? 370 SER B C   1 
ATOM   1179 O O   . SER A  1 370 ? 168.319 199.405 199.422 1.00 76.62  ? 370 SER B O   1 
ATOM   1180 C CB  . SER A  1 370 ? 170.845 197.685 200.603 1.00 60.27  ? 370 SER B CB  1 
ATOM   1181 O OG  . SER A  1 370 ? 171.541 197.156 201.716 1.00 65.95  ? 370 SER B OG  1 
ATOM   1182 N N   . ARG A  1 371 ? 168.213 197.231 198.862 1.00 45.71  ? 371 ARG B N   1 
ATOM   1183 C CA  . ARG A  1 371 ? 167.449 197.507 197.652 1.00 50.57  ? 371 ARG B CA  1 
ATOM   1184 C C   . ARG A  1 371 ? 166.092 198.116 197.975 1.00 56.61  ? 371 ARG B C   1 
ATOM   1185 O O   . ARG A  1 371 ? 165.666 199.081 197.330 1.00 63.75  ? 371 ARG B O   1 
ATOM   1186 C CB  . ARG A  1 371 ? 167.277 196.221 196.855 1.00 62.01  ? 371 ARG B CB  1 
ATOM   1187 C CG  . ARG A  1 371 ? 167.307 196.396 195.372 1.00 54.11  ? 371 ARG B CG  1 
ATOM   1188 C CD  . ARG A  1 371 ? 166.751 195.161 194.713 1.00 59.02  ? 371 ARG B CD  1 
ATOM   1189 N NE  . ARG A  1 371 ? 167.145 193.927 195.381 1.00 57.38  ? 371 ARG B NE  1 
ATOM   1190 C CZ  . ARG A  1 371 ? 166.301 193.086 195.962 1.00 56.11  ? 371 ARG B CZ  1 
ATOM   1191 N NH1 . ARG A  1 371 ? 165.000 193.322 195.989 1.00 54.84  ? 371 ARG B NH1 1 
ATOM   1192 N NH2 . ARG A  1 371 ? 166.773 191.979 196.525 1.00 60.03  ? 371 ARG B NH2 1 
ATOM   1193 N N   . PHE A  1 372 ? 165.394 197.569 198.972 1.00 60.43  ? 372 PHE B N   1 
ATOM   1194 C CA  . PHE A  1 372 ? 164.088 198.110 199.331 1.00 61.05  ? 372 PHE B CA  1 
ATOM   1195 C C   . PHE A  1 372 ? 164.220 199.492 199.955 1.00 68.45  ? 372 PHE B C   1 
ATOM   1196 O O   . PHE A  1 372 ? 163.380 200.368 199.717 1.00 68.59  ? 372 PHE B O   1 
ATOM   1197 C CB  . PHE A  1 372 ? 163.363 197.149 200.271 1.00 63.77  ? 372 PHE B CB  1 
ATOM   1198 C CG  . PHE A  1 372 ? 163.001 195.839 199.632 1.00 70.50  ? 372 PHE B CG  1 
ATOM   1199 C CD1 . PHE A  1 372 ? 162.786 195.756 198.267 1.00 62.99  ? 372 PHE B CD1 1 
ATOM   1200 C CD2 . PHE A  1 372 ? 162.879 194.690 200.395 1.00 72.65  ? 372 PHE B CD2 1 
ATOM   1201 C CE1 . PHE A  1 372 ? 162.456 194.552 197.675 1.00 65.83  ? 372 PHE B CE1 1 
ATOM   1202 C CE2 . PHE A  1 372 ? 162.551 193.483 199.809 1.00 70.24  ? 372 PHE B CE2 1 
ATOM   1203 C CZ  . PHE A  1 372 ? 162.338 193.415 198.447 1.00 69.66  ? 372 PHE B CZ  1 
ATOM   1204 N N   . TRP A  1 373 ? 165.271 199.712 200.750 1.00 63.33  ? 373 TRP B N   1 
ATOM   1205 C CA  . TRP A  1 373 ? 165.513 201.048 201.286 1.00 54.58  ? 373 TRP B CA  1 
ATOM   1206 C C   . TRP A  1 373 ? 165.760 202.054 200.168 1.00 47.06  ? 373 TRP B C   1 
ATOM   1207 O O   . TRP A  1 373 ? 165.236 203.174 200.201 1.00 52.72  ? 373 TRP B O   1 
ATOM   1208 C CB  . TRP A  1 373 ? 166.694 201.013 202.254 1.00 49.82  ? 373 TRP B CB  1 
ATOM   1209 C CG  . TRP A  1 373 ? 167.143 202.360 202.707 1.00 48.26  ? 373 TRP B CG  1 
ATOM   1210 C CD1 . TRP A  1 373 ? 166.728 203.030 203.817 1.00 55.78  ? 373 TRP B CD1 1 
ATOM   1211 C CD2 . TRP A  1 373 ? 168.111 203.199 202.070 1.00 54.34  ? 373 TRP B CD2 1 
ATOM   1212 N NE1 . TRP A  1 373 ? 167.371 204.239 203.908 1.00 61.46  ? 373 TRP B NE1 1 
ATOM   1213 C CE2 . TRP A  1 373 ? 168.226 204.366 202.846 1.00 58.88  ? 373 TRP B CE2 1 
ATOM   1214 C CE3 . TRP A  1 373 ? 168.888 203.078 200.915 1.00 53.46  ? 373 TRP B CE3 1 
ATOM   1215 C CZ2 . TRP A  1 373 ? 169.087 205.405 202.505 1.00 57.54  ? 373 TRP B CZ2 1 
ATOM   1216 C CZ3 . TRP A  1 373 ? 169.739 204.110 200.579 1.00 58.09  ? 373 TRP B CZ3 1 
ATOM   1217 C CH2 . TRP A  1 373 ? 169.834 205.257 201.371 1.00 57.06  ? 373 TRP B CH2 1 
ATOM   1218 N N   . LEU A  1 374 ? 166.548 201.668 199.163 1.00 40.60  ? 374 LEU B N   1 
ATOM   1219 C CA  . LEU A  1 374 ? 166.787 202.552 198.030 1.00 38.60  ? 374 LEU B CA  1 
ATOM   1220 C C   . LEU A  1 374 ? 165.511 202.793 197.237 1.00 48.24  ? 374 LEU B C   1 
ATOM   1221 O O   . LEU A  1 374 ? 165.309 203.893 196.716 1.00 59.44  ? 374 LEU B O   1 
ATOM   1222 C CB  . LEU A  1 374 ? 167.883 201.970 197.133 1.00 31.44  ? 374 LEU B CB  1 
ATOM   1223 C CG  . LEU A  1 374 ? 168.464 202.823 196.000 1.00 31.68  ? 374 LEU B CG  1 
ATOM   1224 C CD1 . LEU A  1 374 ? 167.674 202.680 194.708 1.00 43.57  ? 374 LEU B CD1 1 
ATOM   1225 C CD2 . LEU A  1 374 ? 168.548 204.281 196.416 1.00 44.71  ? 374 LEU B CD2 1 
ATOM   1226 N N   . LEU A  1 375 ? 164.645 201.784 197.128 1.00 41.61  ? 375 LEU B N   1 
ATOM   1227 C CA  . LEU A  1 375 ? 163.367 201.984 196.451 1.00 34.77  ? 375 LEU B CA  1 
ATOM   1228 C C   . LEU A  1 375 ? 162.495 202.985 197.196 1.00 47.78  ? 375 LEU B C   1 
ATOM   1229 O O   . LEU A  1 375 ? 161.890 203.870 196.578 1.00 58.99  ? 375 LEU B O   1 
ATOM   1230 C CB  . LEU A  1 375 ? 162.638 200.652 196.295 1.00 46.59  ? 375 LEU B CB  1 
ATOM   1231 C CG  . LEU A  1 375 ? 162.710 200.060 194.890 1.00 59.53  ? 375 LEU B CG  1 
ATOM   1232 C CD1 . LEU A  1 375 ? 162.112 201.019 193.874 1.00 54.26  ? 375 LEU B CD1 1 
ATOM   1233 C CD2 . LEU A  1 375 ? 164.147 199.752 194.543 1.00 58.97  ? 375 LEU B CD2 1 
ATOM   1234 N N   . LYS A  1 376 ? 162.420 202.865 198.523 1.00 51.63  ? 376 LYS B N   1 
ATOM   1235 C CA  . LYS A  1 376 ? 161.666 203.843 199.302 1.00 55.08  ? 376 LYS B CA  1 
ATOM   1236 C C   . LYS A  1 376 ? 162.248 205.240 199.130 1.00 58.94  ? 376 LYS B C   1 
ATOM   1237 O O   . LYS A  1 376 ? 161.506 206.219 198.987 1.00 57.13  ? 376 LYS B O   1 
ATOM   1238 C CB  . LYS A  1 376 ? 161.645 203.458 200.781 1.00 52.89  ? 376 LYS B CB  1 
ATOM   1239 C CG  . LYS A  1 376 ? 161.201 202.038 201.065 1.00 56.97  ? 376 LYS B CG  1 
ATOM   1240 C CD  . LYS A  1 376 ? 159.772 201.793 200.623 1.00 62.75  ? 376 LYS B CD  1 
ATOM   1241 C CE  . LYS A  1 376 ? 159.361 200.355 200.888 1.00 59.09  ? 376 LYS B CE  1 
ATOM   1242 N NZ  . LYS A  1 376 ? 158.217 199.944 200.033 1.00 56.74  ? 376 LYS B NZ  1 
ATOM   1243 N N   . LEU A  1 377 ? 163.579 205.350 199.141 1.00 55.05  ? 377 LEU B N   1 
ATOM   1244 C CA  . LEU A  1 377 ? 164.212 206.655 198.985 1.00 36.85  ? 377 LEU B CA  1 
ATOM   1245 C C   . LEU A  1 377 ? 163.934 207.254 197.613 1.00 42.20  ? 377 LEU B C   1 
ATOM   1246 O O   . LEU A  1 377 ? 163.677 208.456 197.498 1.00 60.41  ? 377 LEU B O   1 
ATOM   1247 C CB  . LEU A  1 377 ? 165.714 206.543 199.216 1.00 41.73  ? 377 LEU B CB  1 
ATOM   1248 C CG  . LEU A  1 377 ? 166.298 207.826 199.788 1.00 47.76  ? 377 LEU B CG  1 
ATOM   1249 C CD1 . LEU A  1 377 ? 165.631 208.118 201.116 1.00 50.68  ? 377 LEU B CD1 1 
ATOM   1250 C CD2 . LEU A  1 377 ? 167.802 207.712 199.938 1.00 46.86  ? 377 LEU B CD2 1 
ATOM   1251 N N   . LEU A  1 378 ? 164.002 206.440 196.559 1.00 32.23  ? 378 LEU B N   1 
ATOM   1252 C CA  . LEU A  1 378 ? 163.709 206.940 195.220 1.00 33.42  ? 378 LEU B CA  1 
ATOM   1253 C C   . LEU A  1 378 ? 162.257 207.380 195.107 1.00 46.28  ? 378 LEU B C   1 
ATOM   1254 O O   . LEU A  1 378 ? 161.956 208.408 194.487 1.00 54.73  ? 378 LEU B O   1 
ATOM   1255 C CB  . LEU A  1 378 ? 164.030 205.872 194.177 1.00 34.69  ? 378 LEU B CB  1 
ATOM   1256 C CG  . LEU A  1 378 ? 165.450 205.876 193.610 1.00 42.95  ? 378 LEU B CG  1 
ATOM   1257 C CD1 . LEU A  1 378 ? 165.550 204.928 192.429 1.00 51.29  ? 378 LEU B CD1 1 
ATOM   1258 C CD2 . LEU A  1 378 ? 165.860 207.279 193.204 1.00 43.70  ? 378 LEU B CD2 1 
ATOM   1259 N N   . PHE A  1 379 ? 161.340 206.613 195.702 1.00 45.09  ? 379 PHE B N   1 
ATOM   1260 C CA  . PHE A  1 379 ? 159.938 207.014 195.705 1.00 46.15  ? 379 PHE B CA  1 
ATOM   1261 C C   . PHE A  1 379 ? 159.749 208.341 196.427 1.00 49.29  ? 379 PHE B C   1 
ATOM   1262 O O   . PHE A  1 379 ? 159.002 209.208 195.962 1.00 57.26  ? 379 PHE B O   1 
ATOM   1263 C CB  . PHE A  1 379 ? 159.083 205.924 196.348 1.00 48.23  ? 379 PHE B CB  1 
ATOM   1264 C CG  . PHE A  1 379 ? 157.684 206.361 196.659 1.00 54.37  ? 379 PHE B CG  1 
ATOM   1265 C CD1 . PHE A  1 379 ? 156.785 206.625 195.641 1.00 49.19  ? 379 PHE B CD1 1 
ATOM   1266 C CD2 . PHE A  1 379 ? 157.267 206.507 197.971 1.00 53.18  ? 379 PHE B CD2 1 
ATOM   1267 C CE1 . PHE A  1 379 ? 155.498 207.027 195.925 1.00 49.45  ? 379 PHE B CE1 1 
ATOM   1268 C CE2 . PHE A  1 379 ? 155.981 206.909 198.261 1.00 51.05  ? 379 PHE B CE2 1 
ATOM   1269 C CZ  . PHE A  1 379 ? 155.095 207.169 197.237 1.00 53.54  ? 379 PHE B CZ  1 
ATOM   1270 N N   . ARG A  1 380 ? 160.421 208.517 197.566 1.00 44.55  ? 380 ARG B N   1 
ATOM   1271 C CA  . ARG A  1 380 ? 160.310 209.775 198.298 1.00 49.07  ? 380 ARG B CA  1 
ATOM   1272 C C   . ARG A  1 380 ? 160.892 210.937 197.501 1.00 48.89  ? 380 ARG B C   1 
ATOM   1273 O O   . ARG A  1 380 ? 160.324 212.035 197.491 1.00 52.04  ? 380 ARG B O   1 
ATOM   1274 C CB  . ARG A  1 380 ? 161.001 209.657 199.656 1.00 41.91  ? 380 ARG B CB  1 
ATOM   1275 C CG  . ARG A  1 380 ? 160.064 209.306 200.796 1.00 36.54  ? 380 ARG B CG  1 
ATOM   1276 C CD  . ARG A  1 380 ? 160.830 209.006 202.069 1.00 43.13  ? 380 ARG B CD  1 
ATOM   1277 N NE  . ARG A  1 380 ? 161.615 210.150 202.514 1.00 51.02  ? 380 ARG B NE  1 
ATOM   1278 C CZ  . ARG A  1 380 ? 162.759 210.060 203.179 1.00 59.44  ? 380 ARG B CZ  1 
ATOM   1279 N NH1 . ARG A  1 380 ? 163.285 208.888 203.496 1.00 58.55  ? 380 ARG B NH1 1 
ATOM   1280 N NH2 . ARG A  1 380 ? 163.390 211.175 203.537 1.00 49.37  ? 380 ARG B NH2 1 
ATOM   1281 N N   . VAL A  1 381 ? 162.024 210.717 196.829 1.00 40.08  ? 381 VAL B N   1 
ATOM   1282 C CA  . VAL A  1 381 ? 162.692 211.811 196.134 1.00 31.76  ? 381 VAL B CA  1 
ATOM   1283 C C   . VAL A  1 381 ? 161.946 212.193 194.862 1.00 39.42  ? 381 VAL B C   1 
ATOM   1284 O O   . VAL A  1 381 ? 161.995 213.352 194.437 1.00 57.08  ? 381 VAL B O   1 
ATOM   1285 C CB  . VAL A  1 381 ? 164.165 211.452 195.854 1.00 30.21  ? 381 VAL B CB  1 
ATOM   1286 C CG1 . VAL A  1 381 ? 164.306 210.645 194.579 1.00 41.50  ? 381 VAL B CG1 1 
ATOM   1287 C CG2 . VAL A  1 381 ? 165.006 212.707 195.783 1.00 35.10  ? 381 VAL B CG2 1 
ATOM   1288 N N   . PHE A  1 382 ? 161.244 211.248 194.233 1.00 34.73  ? 382 PHE B N   1 
ATOM   1289 C CA  . PHE A  1 382 ? 160.465 211.591 193.049 1.00 45.00  ? 382 PHE B CA  1 
ATOM   1290 C C   . PHE A  1 382 ? 159.075 212.109 193.390 1.00 49.45  ? 382 PHE B C   1 
ATOM   1291 O O   . PHE A  1 382 ? 158.327 212.483 192.480 1.00 53.45  ? 382 PHE B O   1 
ATOM   1292 C CB  . PHE A  1 382 ? 160.359 210.386 192.113 1.00 44.81  ? 382 PHE B CB  1 
ATOM   1293 C CG  . PHE A  1 382 ? 161.453 210.325 191.088 1.00 42.16  ? 382 PHE B CG  1 
ATOM   1294 C CD1 . PHE A  1 382 ? 162.752 210.029 191.460 1.00 41.79  ? 382 PHE B CD1 1 
ATOM   1295 C CD2 . PHE A  1 382 ? 161.186 210.577 189.754 1.00 48.14  ? 382 PHE B CD2 1 
ATOM   1296 C CE1 . PHE A  1 382 ? 163.760 209.975 190.521 1.00 39.96  ? 382 PHE B CE1 1 
ATOM   1297 C CE2 . PHE A  1 382 ? 162.192 210.526 188.810 1.00 48.78  ? 382 PHE B CE2 1 
ATOM   1298 C CZ  . PHE A  1 382 ? 163.481 210.224 189.196 1.00 48.24  ? 382 PHE B CZ  1 
ATOM   1299 N N   . THR A  1 383 ? 158.720 212.141 194.671 1.00 48.04  ? 383 THR B N   1 
ATOM   1300 C CA  . THR A  1 383 ? 157.476 212.730 195.150 1.00 52.15  ? 383 THR B CA  1 
ATOM   1301 C C   . THR A  1 383 ? 157.827 213.754 196.220 1.00 58.21  ? 383 THR B C   1 
ATOM   1302 O O   . THR A  1 383 ? 157.267 213.740 197.321 1.00 54.29  ? 383 THR B O   1 
ATOM   1303 C CB  . THR A  1 383 ? 156.536 211.661 195.700 1.00 49.24  ? 383 THR B CB  1 
ATOM   1304 O OG1 . THR A  1 383 ? 157.267 210.792 196.571 1.00 42.99  ? 383 THR B OG1 1 
ATOM   1305 C CG2 . THR A  1 383 ? 155.942 210.845 194.566 1.00 49.21  ? 383 THR B CG2 1 
ATOM   1306 N N   . ALA A  1 384 ? 158.775 214.629 195.888 1.00 59.05  ? 384 ALA B N   1 
ATOM   1307 C CA  . ALA A  1 384 ? 159.464 215.440 196.891 1.00 57.95  ? 384 ALA B CA  1 
ATOM   1308 C C   . ALA A  1 384 ? 158.551 216.320 197.736 1.00 60.15  ? 384 ALA B C   1 
ATOM   1309 O O   . ALA A  1 384 ? 158.689 216.294 198.971 1.00 64.29  ? 384 ALA B O   1 
ATOM   1310 C CB  . ALA A  1 384 ? 160.538 216.279 196.194 1.00 53.90  ? 384 ALA B CB  1 
ATOM   1311 N N   . PRO A  1 385 ? 157.635 217.119 197.175 1.00 52.86  ? 385 PRO B N   1 
ATOM   1312 C CA  . PRO A  1 385 ? 156.924 218.096 198.020 1.00 43.14  ? 385 PRO B CA  1 
ATOM   1313 C C   . PRO A  1 385 ? 156.110 217.477 199.142 1.00 50.66  ? 385 PRO B C   1 
ATOM   1314 O O   . PRO A  1 385 ? 155.977 218.094 200.206 1.00 53.49  ? 385 PRO B O   1 
ATOM   1315 C CB  . PRO A  1 385 ? 156.025 218.837 197.020 1.00 48.57  ? 385 PRO B CB  1 
ATOM   1316 C CG  . PRO A  1 385 ? 155.893 217.918 195.867 1.00 54.33  ? 385 PRO B CG  1 
ATOM   1317 C CD  . PRO A  1 385 ? 157.194 217.200 195.771 1.00 49.95  ? 385 PRO B CD  1 
ATOM   1318 N N   . PHE A  1 386 ? 155.575 216.276 198.950 1.00 56.42  ? 386 PHE B N   1 
ATOM   1319 C CA  . PHE A  1 386 ? 154.603 215.705 199.873 1.00 54.28  ? 386 PHE B CA  1 
ATOM   1320 C C   . PHE A  1 386 ? 155.231 214.948 201.037 1.00 54.58  ? 386 PHE B C   1 
ATOM   1321 O O   . PHE A  1 386 ? 154.496 214.468 201.906 1.00 54.47  ? 386 PHE B O   1 
ATOM   1322 C CB  . PHE A  1 386 ? 153.651 214.776 199.115 1.00 52.52  ? 386 PHE B CB  1 
ATOM   1323 C CG  . PHE A  1 386 ? 153.090 215.381 197.862 1.00 56.61  ? 386 PHE B CG  1 
ATOM   1324 C CD1 . PHE A  1 386 ? 152.371 216.562 197.910 1.00 56.14  ? 386 PHE B CD1 1 
ATOM   1325 C CD2 . PHE A  1 386 ? 153.284 214.771 196.636 1.00 53.42  ? 386 PHE B CD2 1 
ATOM   1326 C CE1 . PHE A  1 386 ? 151.855 217.122 196.760 1.00 55.03  ? 386 PHE B CE1 1 
ATOM   1327 C CE2 . PHE A  1 386 ? 152.771 215.326 195.481 1.00 55.93  ? 386 PHE B CE2 1 
ATOM   1328 C CZ  . PHE A  1 386 ? 152.055 216.504 195.544 1.00 55.60  ? 386 PHE B CZ  1 
ATOM   1329 N N   . HIS A  1 387 ? 156.555 214.830 201.088 1.00 59.61  ? 387 HIS B N   1 
ATOM   1330 C CA  . HIS A  1 387 ? 157.229 214.053 202.119 1.00 59.88  ? 387 HIS B CA  1 
ATOM   1331 C C   . HIS A  1 387 ? 158.186 214.930 202.911 1.00 55.34  ? 387 HIS B C   1 
ATOM   1332 O O   . HIS A  1 387 ? 158.912 215.749 202.339 1.00 53.96  ? 387 HIS B O   1 
ATOM   1333 C CB  . HIS A  1 387 ? 158.001 212.877 201.515 1.00 57.53  ? 387 HIS B CB  1 
ATOM   1334 C CG  . HIS A  1 387 ? 157.131 211.867 200.837 1.00 59.99  ? 387 HIS B CG  1 
ATOM   1335 N ND1 . HIS A  1 387 ? 156.760 211.970 199.514 1.00 50.13  ? 387 HIS B ND1 1 
ATOM   1336 C CD2 . HIS A  1 387 ? 156.560 210.730 201.301 1.00 59.02  ? 387 HIS B CD2 1 
ATOM   1337 C CE1 . HIS A  1 387 ? 155.996 210.942 199.193 1.00 54.93  ? 387 HIS B CE1 1 
ATOM   1338 N NE2 . HIS A  1 387 ? 155.860 210.174 200.259 1.00 57.83  ? 387 HIS B NE2 1 
ATOM   1339 N N   . LYS A  1 388 ? 158.182 214.752 204.230 1.00 55.42  ? 388 LYS B N   1 
ATOM   1340 C CA  . LYS A  1 388 ? 159.179 215.396 205.072 1.00 57.05  ? 388 LYS B CA  1 
ATOM   1341 C C   . LYS A  1 388 ? 160.564 214.914 204.672 1.00 64.26  ? 388 LYS B C   1 
ATOM   1342 O O   . LYS A  1 388 ? 160.790 213.713 204.496 1.00 68.32  ? 388 LYS B O   1 
ATOM   1343 C CB  . LYS A  1 388 ? 158.909 215.090 206.546 1.00 62.59  ? 388 LYS B CB  1 
ATOM   1344 C CG  . LYS A  1 388 ? 159.122 216.266 207.491 1.00 60.48  ? 388 LYS B CG  1 
ATOM   1345 C CD  . LYS A  1 388 ? 160.579 216.692 207.551 1.00 57.95  ? 388 LYS B CD  1 
ATOM   1346 C CE  . LYS A  1 388 ? 160.737 218.025 208.262 1.00 63.45  ? 388 LYS B CE  1 
ATOM   1347 N NZ  . LYS A  1 388 ? 162.026 218.689 207.923 1.00 64.21  ? 388 LYS B NZ  1 
ATOM   1348 N N   . VAL A  1 389 ? 161.490 215.849 204.526 1.00 55.56  ? 389 VAL B N   1 
ATOM   1349 C CA  . VAL A  1 389 ? 162.808 215.532 203.995 1.00 54.75  ? 389 VAL B CA  1 
ATOM   1350 C C   . VAL A  1 389 ? 163.731 215.090 205.123 1.00 52.54  ? 389 VAL B C   1 
ATOM   1351 O O   . VAL A  1 389 ? 163.700 215.633 206.235 1.00 52.61  ? 389 VAL B O   1 
ATOM   1352 C CB  . VAL A  1 389 ? 163.383 216.739 203.231 1.00 45.87  ? 389 VAL B CB  1 
ATOM   1353 C CG1 . VAL A  1 389 ? 163.758 217.843 204.190 1.00 49.29  ? 389 VAL B CG1 1 
ATOM   1354 C CG2 . VAL A  1 389 ? 164.583 216.321 202.403 1.00 52.18  ? 389 VAL B CG2 1 
ATOM   1355 N N   . GLY A  1 390 ? 164.532 214.062 204.844 1.00 41.47  ? 390 GLY B N   1 
ATOM   1356 C CA  . GLY A  1 390 ? 165.646 213.697 205.691 1.00 46.48  ? 390 GLY B CA  1 
ATOM   1357 C C   . GLY A  1 390 ? 166.950 213.947 204.957 1.00 49.70  ? 390 GLY B C   1 
ATOM   1358 O O   . GLY A  1 390 ? 166.963 214.484 203.848 1.00 52.79  ? 390 GLY B O   1 
ATOM   1359 N N   . PHE A  1 391 ? 168.048 213.550 205.601 1.00 43.19  ? 391 PHE B N   1 
ATOM   1360 C CA  . PHE A  1 391 ? 169.336 213.681 204.930 1.00 35.64  ? 391 PHE B CA  1 
ATOM   1361 C C   . PHE A  1 391 ? 169.429 212.748 203.735 1.00 34.13  ? 391 PHE B C   1 
ATOM   1362 O O   . PHE A  1 391 ? 170.060 213.086 202.730 1.00 41.08  ? 391 PHE B O   1 
ATOM   1363 C CB  . PHE A  1 391 ? 170.493 213.413 205.886 1.00 37.33  ? 391 PHE B CB  1 
ATOM   1364 C CG  . PHE A  1 391 ? 171.837 213.562 205.237 1.00 33.24  ? 391 PHE B CG  1 
ATOM   1365 C CD1 . PHE A  1 391 ? 172.460 212.481 204.638 1.00 33.36  ? 391 PHE B CD1 1 
ATOM   1366 C CD2 . PHE A  1 391 ? 172.459 214.793 205.187 1.00 35.47  ? 391 PHE B CD2 1 
ATOM   1367 C CE1 . PHE A  1 391 ? 173.685 212.623 204.027 1.00 32.25  ? 391 PHE B CE1 1 
ATOM   1368 C CE2 . PHE A  1 391 ? 173.684 214.938 204.576 1.00 33.43  ? 391 PHE B CE2 1 
ATOM   1369 C CZ  . PHE A  1 391 ? 174.298 213.852 203.997 1.00 32.98  ? 391 PHE B CZ  1 
ATOM   1370 N N   . ALA A  1 392 ? 168.834 211.560 203.833 1.00 31.36  ? 392 ALA B N   1 
ATOM   1371 C CA  . ALA A  1 392 ? 168.915 210.611 202.730 1.00 31.96  ? 392 ALA B CA  1 
ATOM   1372 C C   . ALA A  1 392 ? 168.232 211.155 201.482 1.00 39.05  ? 392 ALA B C   1 
ATOM   1373 O O   . ALA A  1 392 ? 168.762 211.031 200.372 1.00 35.07  ? 392 ALA B O   1 
ATOM   1374 C CB  . ALA A  1 392 ? 168.302 209.277 203.151 1.00 27.78  ? 392 ALA B CB  1 
ATOM   1375 N N   . ASP A  1 393 ? 167.063 211.776 201.647 1.00 48.73  ? 393 ASP B N   1 
ATOM   1376 C CA  . ASP A  1 393 ? 166.331 212.322 200.508 1.00 40.74  ? 393 ASP B CA  1 
ATOM   1377 C C   . ASP A  1 393 ? 167.108 213.452 199.844 1.00 40.54  ? 393 ASP B C   1 
ATOM   1378 O O   . ASP A  1 393 ? 167.271 213.474 198.619 1.00 54.41  ? 393 ASP B O   1 
ATOM   1379 C CB  . ASP A  1 393 ? 164.958 212.810 200.967 1.00 38.33  ? 393 ASP B CB  1 
ATOM   1380 C CG  . ASP A  1 393 ? 163.863 212.455 199.994 1.00 52.40  ? 393 ASP B CG  1 
ATOM   1381 O OD1 . ASP A  1 393 ? 164.166 211.770 198.998 1.00 54.06  ? 393 ASP B OD1 1 
ATOM   1382 O OD2 . ASP A  1 393 ? 162.703 212.857 200.223 1.00 60.24  ? 393 ASP B OD2 1 
ATOM   1383 N N   . PHE A  1 394 ? 167.594 214.401 200.646 1.00 34.66  ? 394 PHE B N   1 
ATOM   1384 C CA  . PHE A  1 394 ? 168.414 215.493 200.131 1.00 39.44  ? 394 PHE B CA  1 
ATOM   1385 C C   . PHE A  1 394 ? 169.659 214.973 199.424 1.00 41.93  ? 394 PHE B C   1 
ATOM   1386 O O   . PHE A  1 394 ? 170.012 215.439 198.331 1.00 45.75  ? 394 PHE B O   1 
ATOM   1387 C CB  . PHE A  1 394 ? 168.791 216.414 201.290 1.00 33.32  ? 394 PHE B CB  1 
ATOM   1388 C CG  . PHE A  1 394 ? 170.128 217.071 201.142 1.00 31.70  ? 394 PHE B CG  1 
ATOM   1389 C CD1 . PHE A  1 394 ? 170.321 218.096 200.240 1.00 39.87  ? 394 PHE B CD1 1 
ATOM   1390 C CD2 . PHE A  1 394 ? 171.198 216.655 201.912 1.00 42.51  ? 394 PHE B CD2 1 
ATOM   1391 C CE1 . PHE A  1 394 ? 171.551 218.699 200.116 1.00 46.84  ? 394 PHE B CE1 1 
ATOM   1392 C CE2 . PHE A  1 394 ? 172.431 217.250 201.787 1.00 42.69  ? 394 PHE B CE2 1 
ATOM   1393 C CZ  . PHE A  1 394 ? 172.609 218.272 200.886 1.00 44.85  ? 394 PHE B CZ  1 
ATOM   1394 N N   . TRP A  1 395 ? 170.337 214.004 200.038 1.00 36.12  ? 395 TRP B N   1 
ATOM   1395 C CA  . TRP A  1 395 ? 171.572 213.474 199.480 1.00 28.03  ? 395 TRP B CA  1 
ATOM   1396 C C   . TRP A  1 395 ? 171.318 212.797 198.141 1.00 34.60  ? 395 TRP B C   1 
ATOM   1397 O O   . TRP A  1 395 ? 172.021 213.058 197.159 1.00 53.08  ? 395 TRP B O   1 
ATOM   1398 C CB  . TRP A  1 395 ? 172.200 212.506 200.481 1.00 31.21  ? 395 TRP B CB  1 
ATOM   1399 C CG  . TRP A  1 395 ? 173.502 211.932 200.066 1.00 37.32  ? 395 TRP B CG  1 
ATOM   1400 C CD1 . TRP A  1 395 ? 174.733 212.487 200.243 1.00 35.46  ? 395 TRP B CD1 1 
ATOM   1401 C CD2 . TRP A  1 395 ? 173.716 210.674 199.421 1.00 38.98  ? 395 TRP B CD2 1 
ATOM   1402 N NE1 . TRP A  1 395 ? 175.701 211.656 199.741 1.00 48.18  ? 395 TRP B NE1 1 
ATOM   1403 C CE2 . TRP A  1 395 ? 175.102 210.533 199.234 1.00 35.92  ? 395 TRP B CE2 1 
ATOM   1404 C CE3 . TRP A  1 395 ? 172.869 209.653 198.982 1.00 38.85  ? 395 TRP B CE3 1 
ATOM   1405 C CZ2 . TRP A  1 395 ? 175.660 209.420 198.619 1.00 27.81  ? 395 TRP B CZ2 1 
ATOM   1406 C CZ3 . TRP A  1 395 ? 173.425 208.549 198.377 1.00 43.16  ? 395 TRP B CZ3 1 
ATOM   1407 C CH2 . TRP A  1 395 ? 174.807 208.440 198.200 1.00 43.94  ? 395 TRP B CH2 1 
ATOM   1408 N N   . LEU A  1 396 ? 170.291 211.944 198.072 1.00 29.34  ? 396 LEU B N   1 
ATOM   1409 C CA  . LEU A  1 396 ? 169.972 211.275 196.816 1.00 37.53  ? 396 LEU B CA  1 
ATOM   1410 C C   . LEU A  1 396 ? 169.511 212.264 195.755 1.00 36.88  ? 396 LEU B C   1 
ATOM   1411 O O   . LEU A  1 396 ? 169.789 212.067 194.567 1.00 37.08  ? 396 LEU B O   1 
ATOM   1412 C CB  . LEU A  1 396 ? 168.909 210.202 197.044 1.00 41.28  ? 396 LEU B CB  1 
ATOM   1413 C CG  . LEU A  1 396 ? 168.557 209.313 195.849 1.00 39.28  ? 396 LEU B CG  1 
ATOM   1414 C CD1 . LEU A  1 396 ? 169.809 208.871 195.112 1.00 29.65  ? 396 LEU B CD1 1 
ATOM   1415 C CD2 . LEU A  1 396 ? 167.754 208.109 196.301 1.00 44.46  ? 396 LEU B CD2 1 
ATOM   1416 N N   . ALA A  1 397 ? 168.813 213.329 196.153 1.00 33.69  ? 397 ALA B N   1 
ATOM   1417 C CA  . ALA A  1 397 ? 168.431 214.352 195.187 1.00 22.84  ? 397 ALA B CA  1 
ATOM   1418 C C   . ALA A  1 397 ? 169.656 215.036 194.598 1.00 35.30  ? 397 ALA B C   1 
ATOM   1419 O O   . ALA A  1 397 ? 169.716 215.285 193.389 1.00 50.35  ? 397 ALA B O   1 
ATOM   1420 C CB  . ALA A  1 397 ? 167.509 215.372 195.843 1.00 32.64  ? 397 ALA B CB  1 
ATOM   1421 N N   . ASP A  1 398 ? 170.649 215.349 195.434 1.00 33.08  ? 398 ASP B N   1 
ATOM   1422 C CA  . ASP A  1 398 ? 171.886 215.918 194.903 1.00 26.20  ? 398 ASP B CA  1 
ATOM   1423 C C   . ASP A  1 398 ? 172.601 214.936 193.980 1.00 37.57  ? 398 ASP B C   1 
ATOM   1424 O O   . ASP A  1 398 ? 173.121 215.328 192.926 1.00 56.53  ? 398 ASP B O   1 
ATOM   1425 C CB  . ASP A  1 398 ? 172.809 216.354 196.036 1.00 34.69  ? 398 ASP B CB  1 
ATOM   1426 C CG  . ASP A  1 398 ? 172.754 217.843 196.288 1.00 40.92  ? 398 ASP B CG  1 
ATOM   1427 O OD1 . ASP A  1 398 ? 172.741 218.612 195.305 1.00 41.96  ? 398 ASP B OD1 1 
ATOM   1428 O OD2 . ASP A  1 398 ? 172.747 218.249 197.464 1.00 42.79  ? 398 ASP B OD2 1 
ATOM   1429 N N   . GLN A  1 399 ? 172.644 213.656 194.359 1.00 28.07  ? 399 GLN B N   1 
ATOM   1430 C CA  . GLN A  1 399 ? 173.260 212.656 193.489 1.00 25.84  ? 399 GLN B CA  1 
ATOM   1431 C C   . GLN A  1 399 ? 172.565 212.610 192.137 1.00 35.39  ? 399 GLN B C   1 
ATOM   1432 O O   . GLN A  1 399 ? 173.223 212.505 191.096 1.00 36.41  ? 399 GLN B O   1 
ATOM   1433 C CB  . GLN A  1 399 ? 173.231 211.279 194.153 1.00 35.76  ? 399 GLN B CB  1 
ATOM   1434 C CG  . GLN A  1 399 ? 173.762 211.273 195.566 1.00 31.17  ? 399 GLN B CG  1 
ATOM   1435 C CD  . GLN A  1 399 ? 175.200 211.717 195.654 1.00 33.32  ? 399 GLN B CD  1 
ATOM   1436 O OE1 . GLN A  1 399 ? 175.917 211.730 194.661 1.00 42.13  ? 399 GLN B OE1 1 
ATOM   1437 N NE2 . GLN A  1 399 ? 175.614 212.142 196.834 1.00 37.53  ? 399 GLN B NE2 1 
ATOM   1438 N N   . LEU A  1 400 ? 171.235 212.690 192.134 1.00 40.55  ? 400 LEU B N   1 
ATOM   1439 C CA  . LEU A  1 400 ? 170.500 212.762 190.877 1.00 34.48  ? 400 LEU B CA  1 
ATOM   1440 C C   . LEU A  1 400 ? 170.860 214.024 190.107 1.00 37.95  ? 400 LEU B C   1 
ATOM   1441 O O   . LEU A  1 400 ? 170.966 214.001 188.875 1.00 44.98  ? 400 LEU B O   1 
ATOM   1442 C CB  . LEU A  1 400 ? 168.998 212.709 191.146 1.00 34.87  ? 400 LEU B CB  1 
ATOM   1443 C CG  . LEU A  1 400 ? 168.353 211.332 191.048 1.00 37.10  ? 400 LEU B CG  1 
ATOM   1444 C CD1 . LEU A  1 400 ? 166.851 211.452 191.196 1.00 35.87  ? 400 LEU B CD1 1 
ATOM   1445 C CD2 . LEU A  1 400 ? 168.716 210.679 189.730 1.00 42.81  ? 400 LEU B CD2 1 
ATOM   1446 N N   . ASN A  1 401 ? 171.043 215.137 190.819 1.00 46.88  ? 401 ASN B N   1 
ATOM   1447 C CA  . ASN A  1 401 ? 171.425 216.381 190.160 1.00 45.41  ? 401 ASN B CA  1 
ATOM   1448 C C   . ASN A  1 401 ? 172.760 216.234 189.446 1.00 40.97  ? 401 ASN B C   1 
ATOM   1449 O O   . ASN A  1 401 ? 172.963 216.803 188.368 1.00 45.30  ? 401 ASN B O   1 
ATOM   1450 C CB  . ASN A  1 401 ? 171.482 217.520 191.175 1.00 42.61  ? 401 ASN B CB  1 
ATOM   1451 C CG  . ASN A  1 401 ? 171.414 218.880 190.522 1.00 50.79  ? 401 ASN B CG  1 
ATOM   1452 O OD1 . ASN A  1 401 ? 171.386 218.992 189.298 1.00 55.67  ? 401 ASN B OD1 1 
ATOM   1453 N ND2 . ASN A  1 401 ? 171.391 219.925 191.336 1.00 49.16  ? 401 ASN B ND2 1 
ATOM   1454 N N   . SER A  1 402 ? 173.686 215.477 190.032 1.00 41.06  ? 402 SER B N   1 
ATOM   1455 C CA  . SER A  1 402 ? 174.940 215.183 189.349 1.00 41.98  ? 402 SER B CA  1 
ATOM   1456 C C   . SER A  1 402 ? 174.813 214.057 188.332 1.00 49.52  ? 402 SER B C   1 
ATOM   1457 O O   . SER A  1 402 ? 175.700 213.907 187.486 1.00 44.61  ? 402 SER B O   1 
ATOM   1458 C CB  . SER A  1 402 ? 176.023 214.821 190.360 1.00 37.13  ? 402 SER B CB  1 
ATOM   1459 O OG  . SER A  1 402 ? 176.710 215.977 190.803 1.00 41.95  ? 402 SER B OG  1 
ATOM   1460 N N   . LEU A  1 403 ? 173.739 213.270 188.390 1.00 50.53  ? 403 LEU B N   1 
ATOM   1461 C CA  . LEU A  1 403 ? 173.512 212.171 187.462 1.00 44.98  ? 403 LEU B CA  1 
ATOM   1462 C C   . LEU A  1 403 ? 172.410 212.491 186.459 1.00 42.02  ? 403 LEU B C   1 
ATOM   1463 O O   . LEU A  1 403 ? 171.662 211.602 186.048 1.00 54.02  ? 403 LEU B O   1 
ATOM   1464 C CB  . LEU A  1 403 ? 173.176 210.886 188.216 1.00 41.21  ? 403 LEU B CB  1 
ATOM   1465 C CG  . LEU A  1 403 ? 174.292 210.267 189.054 1.00 34.92  ? 403 LEU B CG  1 
ATOM   1466 C CD1 . LEU A  1 403 ? 173.793 209.019 189.759 1.00 37.83  ? 403 LEU B CD1 1 
ATOM   1467 C CD2 . LEU A  1 403 ? 175.491 209.954 188.182 1.00 44.11  ? 403 LEU B CD2 1 
ATOM   1468 N N   . SER A  1 404 ? 172.287 213.760 186.067 1.00 39.15  ? 404 SER B N   1 
ATOM   1469 C CA  . SER A  1 404 ? 171.305 214.119 185.053 1.00 40.86  ? 404 SER B CA  1 
ATOM   1470 C C   . SER A  1 404 ? 171.597 213.447 183.721 1.00 49.55  ? 404 SER B C   1 
ATOM   1471 O O   . SER A  1 404 ? 170.667 213.211 182.940 1.00 57.89  ? 404 SER B O   1 
ATOM   1472 C CB  . SER A  1 404 ? 171.261 215.637 184.873 1.00 44.19  ? 404 SER B CB  1 
ATOM   1473 O OG  . SER A  1 404 ? 172.514 216.135 184.444 1.00 52.29  ? 404 SER B OG  1 
ATOM   1474 N N   . VAL A  1 405 ? 172.862 213.112 183.461 1.00 49.90  ? 405 VAL B N   1 
ATOM   1475 C CA  . VAL A  1 405 ? 173.230 212.497 182.190 1.00 50.11  ? 405 VAL B CA  1 
ATOM   1476 C C   . VAL A  1 405 ? 172.533 211.155 182.030 1.00 48.39  ? 405 VAL B C   1 
ATOM   1477 O O   . VAL A  1 405 ? 172.166 210.760 180.919 1.00 60.77  ? 405 VAL B O   1 
ATOM   1478 C CB  . VAL A  1 405 ? 174.758 212.351 182.086 1.00 53.41  ? 405 VAL B CB  1 
ATOM   1479 C CG1 . VAL A  1 405 ? 175.171 212.144 180.638 1.00 48.13  ? 405 VAL B CG1 1 
ATOM   1480 C CG2 . VAL A  1 405 ? 175.456 213.553 182.696 1.00 57.01  ? 405 VAL B CG2 1 
ATOM   1481 N N   . ILE A  1 406 ? 172.347 210.429 183.133 1.00 42.02  ? 406 ILE B N   1 
ATOM   1482 C CA  . ILE A  1 406 ? 171.665 209.139 183.070 1.00 38.60  ? 406 ILE B CA  1 
ATOM   1483 C C   . ILE A  1 406 ? 170.218 209.322 182.628 1.00 46.25  ? 406 ILE B C   1 
ATOM   1484 O O   . ILE A  1 406 ? 169.711 208.580 181.779 1.00 52.51  ? 406 ILE B O   1 
ATOM   1485 C CB  . ILE A  1 406 ? 171.758 208.420 184.427 1.00 41.62  ? 406 ILE B CB  1 
ATOM   1486 C CG1 . ILE A  1 406 ? 173.127 207.760 184.582 1.00 45.66  ? 406 ILE B CG1 1 
ATOM   1487 C CG2 . ILE A  1 406 ? 170.655 207.390 184.565 1.00 44.20  ? 406 ILE B CG2 1 
ATOM   1488 C CD1 . ILE A  1 406 ? 173.589 207.654 186.013 1.00 56.73  ? 406 ILE B CD1 1 
ATOM   1489 N N   . LEU A  1 407 ? 169.531 210.315 183.198 1.00 50.17  ? 407 LEU B N   1 
ATOM   1490 C CA  . LEU A  1 407 ? 168.148 210.577 182.807 1.00 43.87  ? 407 LEU B CA  1 
ATOM   1491 C C   . LEU A  1 407 ? 168.060 211.022 181.353 1.00 46.01  ? 407 LEU B C   1 
ATOM   1492 O O   . LEU A  1 407 ? 167.161 210.596 180.615 1.00 57.56  ? 407 LEU B O   1 
ATOM   1493 C CB  . LEU A  1 407 ? 167.534 211.630 183.729 1.00 46.10  ? 407 LEU B CB  1 
ATOM   1494 C CG  . LEU A  1 407 ? 167.147 211.176 185.138 1.00 47.08  ? 407 LEU B CG  1 
ATOM   1495 C CD1 . LEU A  1 407 ? 168.310 211.329 186.100 1.00 46.27  ? 407 LEU B CD1 1 
ATOM   1496 C CD2 . LEU A  1 407 ? 165.939 211.951 185.632 1.00 49.06  ? 407 LEU B CD2 1 
ATOM   1497 N N   . MET A  1 408 ? 168.988 211.879 180.923 1.00 51.67  ? 408 MET B N   1 
ATOM   1498 C CA  . MET A  1 408 ? 169.007 212.312 179.530 1.00 56.97  ? 408 MET B CA  1 
ATOM   1499 C C   . MET A  1 408 ? 169.248 211.136 178.591 1.00 68.48  ? 408 MET B C   1 
ATOM   1500 O O   . MET A  1 408 ? 168.629 211.042 177.525 1.00 70.34  ? 408 MET B O   1 
ATOM   1501 C CB  . MET A  1 408 ? 170.074 213.388 179.342 1.00 53.96  ? 408 MET B CB  1 
ATOM   1502 C CG  . MET A  1 408 ? 169.936 214.546 180.314 1.00 60.59  ? 408 MET B CG  1 
ATOM   1503 S SD  . MET A  1 408 ? 170.859 216.011 179.835 1.00 74.77  ? 408 MET B SD  1 
ATOM   1504 C CE  . MET A  1 408 ? 170.563 215.999 178.080 1.00 69.42  ? 408 MET B CE  1 
ATOM   1505 N N   . ASP A  1 409 ? 170.138 210.220 178.978 1.00 60.08  ? 409 ASP B N   1 
ATOM   1506 C CA  . ASP A  1 409 ? 170.413 209.048 178.155 1.00 41.00  ? 409 ASP B CA  1 
ATOM   1507 C C   . ASP A  1 409 ? 169.215 208.111 178.108 1.00 43.99  ? 409 ASP B C   1 
ATOM   1508 O O   . ASP A  1 409 ? 168.941 207.503 177.071 1.00 53.86  ? 409 ASP B O   1 
ATOM   1509 C CB  . ASP A  1 409 ? 171.642 208.319 178.687 1.00 46.57  ? 409 ASP B CB  1 
ATOM   1510 C CG  . ASP A  1 409 ? 172.933 208.977 178.262 1.00 52.93  ? 409 ASP B CG  1 
ATOM   1511 O OD1 . ASP A  1 409 ? 172.903 210.171 177.899 1.00 49.41  ? 409 ASP B OD1 1 
ATOM   1512 O OD2 . ASP A  1 409 ? 173.979 208.301 178.294 1.00 54.87  ? 409 ASP B OD2 1 
ATOM   1513 N N   . LEU A  1 410 ? 168.499 207.969 179.224 1.00 54.48  ? 410 LEU B N   1 
ATOM   1514 C CA  . LEU A  1 410 ? 167.285 207.159 179.226 1.00 52.39  ? 410 LEU B CA  1 
ATOM   1515 C C   . LEU A  1 410 ? 166.235 207.754 178.297 1.00 56.39  ? 410 LEU B C   1 
ATOM   1516 O O   . LEU A  1 410 ? 165.573 207.029 177.541 1.00 63.95  ? 410 LEU B O   1 
ATOM   1517 C CB  . LEU A  1 410 ? 166.745 207.043 180.651 1.00 56.30  ? 410 LEU B CB  1 
ATOM   1518 C CG  . LEU A  1 410 ? 166.031 205.761 181.081 1.00 59.40  ? 410 LEU B CG  1 
ATOM   1519 C CD1 . LEU A  1 410 ? 165.847 205.761 182.588 1.00 58.14  ? 410 LEU B CD1 1 
ATOM   1520 C CD2 . LEU A  1 410 ? 164.693 205.603 180.385 1.00 64.78  ? 410 LEU B CD2 1 
ATOM   1521 N N   . GLU A  1 411 ? 166.070 209.079 178.340 1.00 60.34  ? 411 GLU B N   1 
ATOM   1522 C CA  . GLU A  1 411 ? 165.130 209.736 177.439 1.00 61.36  ? 411 GLU B CA  1 
ATOM   1523 C C   . GLU A  1 411 ? 165.545 209.536 175.986 1.00 66.53  ? 411 GLU B C   1 
ATOM   1524 O O   . GLU A  1 411 ? 164.701 209.271 175.118 1.00 69.60  ? 411 GLU B O   1 
ATOM   1525 C CB  . GLU A  1 411 ? 165.034 211.223 177.796 1.00 61.94  ? 411 GLU B CB  1 
ATOM   1526 C CG  . GLU A  1 411 ? 163.899 212.015 177.140 1.00 70.74  ? 411 GLU B CG  1 
ATOM   1527 C CD  . GLU A  1 411 ? 164.016 212.123 175.634 1.00 69.65  ? 411 GLU B CD  1 
ATOM   1528 O OE1 . GLU A  1 411 ? 165.100 212.505 175.149 1.00 67.01  ? 411 GLU B OE1 1 
ATOM   1529 O OE2 . GLU A  1 411 ? 163.027 211.819 174.937 1.00 70.47  ? 411 GLU B OE2 1 
ATOM   1530 N N   . TYR A  1 412 ? 166.845 209.654 175.703 1.00 63.37  ? 412 TYR B N   1 
ATOM   1531 C CA  . TYR A  1 412 ? 167.325 209.431 174.344 1.00 64.20  ? 412 TYR B CA  1 
ATOM   1532 C C   . TYR A  1 412 ? 167.080 207.995 173.902 1.00 65.30  ? 412 TYR B C   1 
ATOM   1533 O O   . TYR A  1 412 ? 166.714 207.750 172.751 1.00 67.78  ? 412 TYR B O   1 
ATOM   1534 C CB  . TYR A  1 412 ? 168.809 209.768 174.233 1.00 60.82  ? 412 TYR B CB  1 
ATOM   1535 C CG  . TYR A  1 412 ? 169.348 209.540 172.842 1.00 62.98  ? 412 TYR B CG  1 
ATOM   1536 C CD1 . TYR A  1 412 ? 168.939 210.336 171.783 1.00 65.23  ? 412 TYR B CD1 1 
ATOM   1537 C CD2 . TYR A  1 412 ? 170.246 208.517 172.582 1.00 57.16  ? 412 TYR B CD2 1 
ATOM   1538 C CE1 . TYR A  1 412 ? 169.420 210.130 170.508 1.00 63.74  ? 412 TYR B CE1 1 
ATOM   1539 C CE2 . TYR A  1 412 ? 170.732 208.303 171.308 1.00 61.96  ? 412 TYR B CE2 1 
ATOM   1540 C CZ  . TYR A  1 412 ? 170.315 209.112 170.276 1.00 63.89  ? 412 TYR B CZ  1 
ATOM   1541 O OH  . TYR A  1 412 ? 170.794 208.906 169.004 1.00 62.71  ? 412 TYR B OH  1 
ATOM   1542 N N   . MET A  1 413 ? 167.293 207.033 174.800 1.00 64.53  ? 413 MET B N   1 
ATOM   1543 C CA  . MET A  1 413 ? 167.017 205.636 174.483 1.00 61.56  ? 413 MET B CA  1 
ATOM   1544 C C   . MET A  1 413 ? 165.554 205.441 174.118 1.00 66.58  ? 413 MET B C   1 
ATOM   1545 O O   . MET A  1 413 ? 165.230 204.796 173.112 1.00 70.59  ? 413 MET B O   1 
ATOM   1546 C CB  . MET A  1 413 ? 167.390 204.753 175.673 1.00 59.92  ? 413 MET B CB  1 
ATOM   1547 C CG  . MET A  1 413 ? 167.466 203.269 175.369 1.00 59.75  ? 413 MET B CG  1 
ATOM   1548 S SD  . MET A  1 413 ? 167.454 202.278 176.872 1.00 67.41  ? 413 MET B SD  1 
ATOM   1549 C CE  . MET A  1 413 ? 168.266 203.397 178.010 1.00 63.62  ? 413 MET B CE  1 
ATOM   1550 N N   . ILE A  1 414 ? 164.654 206.004 174.926 1.00 63.17  ? 414 ILE B N   1 
ATOM   1551 C CA  . ILE A  1 414 ? 163.226 205.832 174.676 1.00 57.99  ? 414 ILE B CA  1 
ATOM   1552 C C   . ILE A  1 414 ? 162.847 206.440 173.331 1.00 61.67  ? 414 ILE B C   1 
ATOM   1553 O O   . ILE A  1 414 ? 162.169 205.806 172.512 1.00 65.91  ? 414 ILE B O   1 
ATOM   1554 C CB  . ILE A  1 414 ? 162.402 206.439 175.824 1.00 57.88  ? 414 ILE B CB  1 
ATOM   1555 C CG1 . ILE A  1 414 ? 162.390 205.495 177.025 1.00 56.00  ? 414 ILE B CG1 1 
ATOM   1556 C CG2 . ILE A  1 414 ? 160.982 206.724 175.369 1.00 69.34  ? 414 ILE B CG2 1 
ATOM   1557 C CD1 . ILE A  1 414 ? 161.778 206.099 178.264 1.00 54.87  ? 414 ILE B CD1 1 
ATOM   1558 N N   . CYS A  1 415 ? 163.300 207.670 173.074 1.00 71.19  ? 415 CYS B N   1 
ATOM   1559 C CA  . CYS A  1 415 ? 162.955 208.323 171.814 1.00 78.89  ? 415 CYS B CA  1 
ATOM   1560 C C   . CYS A  1 415 ? 163.544 207.577 170.623 1.00 81.41  ? 415 CYS B C   1 
ATOM   1561 O O   . CYS A  1 415 ? 162.877 207.408 169.594 1.00 85.01  ? 415 CYS B O   1 
ATOM   1562 C CB  . CYS A  1 415 ? 163.430 209.776 171.821 1.00 77.37  ? 415 CYS B CB  1 
ATOM   1563 S SG  . CYS A  1 415 ? 165.129 210.016 171.246 1.00 82.59  ? 415 CYS B SG  1 
ATOM   1564 N N   . PHE A  1 416 ? 164.803 207.147 170.735 1.00 77.61  ? 416 PHE B N   1 
ATOM   1565 C CA  . PHE A  1 416 ? 165.464 206.450 169.640 1.00 75.55  ? 416 PHE B CA  1 
ATOM   1566 C C   . PHE A  1 416 ? 164.748 205.152 169.308 1.00 78.34  ? 416 PHE B C   1 
ATOM   1567 O O   . PHE A  1 416 ? 164.505 204.853 168.133 1.00 78.69  ? 416 PHE B O   1 
ATOM   1568 C CB  . PHE A  1 416 ? 166.923 206.183 170.009 1.00 79.44  ? 416 PHE B CB  1 
ATOM   1569 C CG  . PHE A  1 416 ? 167.714 205.510 168.928 1.00 78.69  ? 416 PHE B CG  1 
ATOM   1570 C CD1 . PHE A  1 416 ? 167.699 205.997 167.635 1.00 82.07  ? 416 PHE B CD1 1 
ATOM   1571 C CD2 . PHE A  1 416 ? 168.485 204.397 169.210 1.00 74.89  ? 416 PHE B CD2 1 
ATOM   1572 C CE1 . PHE A  1 416 ? 168.431 205.383 166.641 1.00 79.56  ? 416 PHE B CE1 1 
ATOM   1573 C CE2 . PHE A  1 416 ? 169.219 203.779 168.220 1.00 78.80  ? 416 PHE B CE2 1 
ATOM   1574 C CZ  . PHE A  1 416 ? 169.192 204.272 166.934 1.00 77.01  ? 416 PHE B CZ  1 
ATOM   1575 N N   . TYR A  1 417 ? 164.374 204.382 170.331 1.00 81.44  ? 417 TYR B N   1 
ATOM   1576 C CA  . TYR A  1 417 ? 163.684 203.126 170.077 1.00 80.31  ? 417 TYR B CA  1 
ATOM   1577 C C   . TYR A  1 417 ? 162.270 203.354 169.564 1.00 80.46  ? 417 TYR B C   1 
ATOM   1578 O O   . TYR A  1 417 ? 161.758 202.539 168.788 1.00 85.72  ? 417 TYR B O   1 
ATOM   1579 C CB  . TYR A  1 417 ? 163.668 202.271 171.340 1.00 76.25  ? 417 TYR B CB  1 
ATOM   1580 C CG  . TYR A  1 417 ? 164.922 201.450 171.508 1.00 77.48  ? 417 TYR B CG  1 
ATOM   1581 C CD1 . TYR A  1 417 ? 166.078 201.767 170.809 1.00 78.62  ? 417 TYR B CD1 1 
ATOM   1582 C CD2 . TYR A  1 417 ? 164.947 200.349 172.347 1.00 78.54  ? 417 TYR B CD2 1 
ATOM   1583 C CE1 . TYR A  1 417 ? 167.223 201.021 170.952 1.00 76.36  ? 417 TYR B CE1 1 
ATOM   1584 C CE2 . TYR A  1 417 ? 166.089 199.595 172.493 1.00 78.78  ? 417 TYR B CE2 1 
ATOM   1585 C CZ  . TYR A  1 417 ? 167.222 199.936 171.794 1.00 78.71  ? 417 TYR B CZ  1 
ATOM   1586 O OH  . TYR A  1 417 ? 168.360 199.185 171.938 1.00 88.64  ? 417 TYR B OH  1 
ATOM   1587 N N   . SER A  1 418 ? 161.625 204.447 169.972 1.00 76.93  ? 418 SER B N   1 
ATOM   1588 C CA  . SER A  1 418 ? 160.262 204.688 169.519 1.00 79.30  ? 418 SER B CA  1 
ATOM   1589 C C   . SER A  1 418 ? 160.209 205.208 168.084 1.00 82.09  ? 418 SER B C   1 
ATOM   1590 O O   . SER A  1 418 ? 159.277 204.875 167.344 1.00 86.85  ? 418 SER B O   1 
ATOM   1591 C CB  . SER A  1 418 ? 159.558 205.648 170.478 1.00 79.72  ? 418 SER B CB  1 
ATOM   1592 O OG  . SER A  1 418 ? 160.391 206.742 170.805 1.00 78.59  ? 418 SER B OG  1 
ATOM   1593 N N   . LEU A  1 419 ? 161.185 206.015 167.659 1.00 81.89  ? 419 LEU B N   1 
ATOM   1594 C CA  . LEU A  1 419 ? 161.152 206.586 166.314 1.00 83.18  ? 419 LEU B CA  1 
ATOM   1595 C C   . LEU A  1 419 ? 162.270 206.080 165.411 1.00 84.29  ? 419 LEU B C   1 
ATOM   1596 O O   . LEU A  1 419 ? 161.994 205.522 164.345 1.00 82.92  ? 419 LEU B O   1 
ATOM   1597 C CB  . LEU A  1 419 ? 161.192 208.126 166.357 1.00 80.72  ? 419 LEU B CB  1 
ATOM   1598 C CG  . LEU A  1 419 ? 160.149 209.010 167.059 1.00 82.40  ? 419 LEU B CG  1 
ATOM   1599 C CD1 . LEU A  1 419 ? 160.068 208.804 168.559 1.00 78.83  ? 419 LEU B CD1 1 
ATOM   1600 C CD2 . LEU A  1 419 ? 160.415 210.476 166.740 1.00 85.08  ? 419 LEU B CD2 1 
ATOM   1601 N N   . GLU A  1 420 ? 163.530 206.258 165.801 1.00 93.96  ? 420 GLU B N   1 
ATOM   1602 C CA  . GLU A  1 420 ? 164.650 206.149 164.874 1.00 94.41  ? 420 GLU B CA  1 
ATOM   1603 C C   . GLU A  1 420 ? 165.370 204.806 164.945 1.00 93.92  ? 420 GLU B C   1 
ATOM   1604 O O   . GLU A  1 420 ? 166.393 204.632 164.274 1.00 93.72  ? 420 GLU B O   1 
ATOM   1605 C CB  . GLU A  1 420 ? 165.641 207.295 165.132 1.00 93.18  ? 420 GLU B CB  1 
ATOM   1606 C CG  . GLU A  1 420 ? 166.605 207.608 163.990 1.00 92.95  ? 420 GLU B CG  1 
ATOM   1607 C CD  . GLU A  1 420 ? 165.899 207.905 162.682 1.00 95.74  ? 420 GLU B CD  1 
ATOM   1608 O OE1 . GLU A  1 420 ? 164.805 208.507 162.714 1.00 98.72  ? 420 GLU B OE1 1 
ATOM   1609 O OE2 . GLU A  1 420 ? 166.441 207.537 161.619 1.00 92.86  ? 420 GLU B OE2 1 
ATOM   1610 N N   . LEU A  1 421 ? 164.861 203.848 165.722 1.00 92.14  ? 421 LEU B N   1 
ATOM   1611 C CA  . LEU A  1 421 ? 165.589 202.595 165.906 1.00 91.08  ? 421 LEU B CA  1 
ATOM   1612 C C   . LEU A  1 421 ? 165.683 201.788 164.616 1.00 89.71  ? 421 LEU B C   1 
ATOM   1613 O O   . LEU A  1 421 ? 166.686 201.097 164.397 1.00 90.82  ? 421 LEU B O   1 
ATOM   1614 C CB  . LEU A  1 421 ? 164.937 201.760 167.006 1.00 88.20  ? 421 LEU B CB  1 
ATOM   1615 C CG  . LEU A  1 421 ? 165.523 200.361 167.204 1.00 90.39  ? 421 LEU B CG  1 
ATOM   1616 C CD1 . LEU A  1 421 ? 167.006 200.448 167.518 1.00 90.17  ? 421 LEU B CD1 1 
ATOM   1617 C CD2 . LEU A  1 421 ? 164.792 199.623 168.306 1.00 90.17  ? 421 LEU B CD2 1 
ATOM   1618 N N   . LYS A  1 422 ? 164.670 201.867 163.750 1.00 93.37  ? 422 LYS B N   1 
ATOM   1619 C CA  . LYS A  1 422 ? 164.593 201.046 162.541 1.00 93.87  ? 422 LYS B CA  1 
ATOM   1620 C C   . LYS A  1 422 ? 164.604 199.557 162.905 1.00 97.16  ? 422 LYS B C   1 
ATOM   1621 O O   . LYS A  1 422 ? 165.552 198.817 162.636 1.00 99.07  ? 422 LYS B O   1 
ATOM   1622 C CB  . LYS A  1 422 ? 165.720 201.394 161.560 1.00 92.03  ? 422 LYS B CB  1 
ATOM   1623 C CG  . LYS A  1 422 ? 165.843 202.877 161.259 1.00 93.95  ? 422 LYS B CG  1 
ATOM   1624 C CD  . LYS A  1 422 ? 164.508 203.451 160.812 1.00 95.29  ? 422 LYS B CD  1 
ATOM   1625 C CE  . LYS A  1 422 ? 164.557 204.965 160.710 1.00 96.21  ? 422 LYS B CE  1 
ATOM   1626 N NZ  . LYS A  1 422 ? 163.194 205.551 160.581 1.00 94.24  ? 422 LYS B NZ  1 
ATOM   1627 N N   . TRP A  1 423 ? 163.506 199.155 163.555 1.00 91.88  ? 423 TRP B N   1 
ATOM   1628 C CA  . TRP A  1 423 ? 163.359 197.789 164.054 1.00 87.73  ? 423 TRP B CA  1 
ATOM   1629 C C   . TRP A  1 423 ? 163.643 196.755 162.971 1.00 89.60  ? 423 TRP B C   1 
ATOM   1630 O O   . TRP A  1 423 ? 164.260 195.717 163.238 1.00 92.00  ? 423 TRP B O   1 
ATOM   1631 C CB  . TRP A  1 423 ? 161.943 197.594 164.598 1.00 86.65  ? 423 TRP B CB  1 
ATOM   1632 C CG  . TRP A  1 423 ? 161.661 198.308 165.885 1.00 89.98  ? 423 TRP B CG  1 
ATOM   1633 C CD1 . TRP A  1 423 ? 161.040 199.514 166.029 1.00 91.92  ? 423 TRP B CD1 1 
ATOM   1634 C CD2 . TRP A  1 423 ? 161.939 197.841 167.211 1.00 88.12  ? 423 TRP B CD2 1 
ATOM   1635 N NE1 . TRP A  1 423 ? 160.938 199.839 167.358 1.00 92.21  ? 423 TRP B NE1 1 
ATOM   1636 C CE2 . TRP A  1 423 ? 161.479 198.827 168.106 1.00 90.72  ? 423 TRP B CE2 1 
ATOM   1637 C CE3 . TRP A  1 423 ? 162.540 196.691 167.728 1.00 85.50  ? 423 TRP B CE3 1 
ATOM   1638 C CZ2 . TRP A  1 423 ? 161.603 198.698 169.487 1.00 88.44  ? 423 TRP B CZ2 1 
ATOM   1639 C CZ3 . TRP A  1 423 ? 162.663 196.565 169.100 1.00 88.04  ? 423 TRP B CZ3 1 
ATOM   1640 C CH2 . TRP A  1 423 ? 162.197 197.563 169.963 1.00 86.45  ? 423 TRP B CH2 1 
ATOM   1641 N N   . ASP A  1 424 ? 163.192 197.018 161.742 1.00 98.02  ? 424 ASP B N   1 
ATOM   1642 C CA  . ASP A  1 424 ? 163.377 196.059 160.658 1.00 98.44  ? 424 ASP B CA  1 
ATOM   1643 C C   . ASP A  1 424 ? 164.853 195.854 160.337 1.00 100.42 ? 424 ASP B C   1 
ATOM   1644 O O   . ASP A  1 424 ? 165.281 194.732 160.042 1.00 97.55  ? 424 ASP B O   1 
ATOM   1645 C CB  . ASP A  1 424 ? 162.619 196.523 159.414 1.00 97.12  ? 424 ASP B CB  1 
ATOM   1646 C CG  . ASP A  1 424 ? 162.825 197.996 159.122 1.00 98.77  ? 424 ASP B CG  1 
ATOM   1647 O OD1 . ASP A  1 424 ? 163.542 198.663 159.897 1.00 101.39 ? 424 ASP B OD1 1 
ATOM   1648 O OD2 . ASP A  1 424 ? 162.270 198.487 158.117 1.00 96.10  ? 424 ASP B OD2 1 
ATOM   1649 N N   . GLU A  1 425 ? 165.642 196.924 160.377 1.00 105.04 ? 425 GLU B N   1 
ATOM   1650 C CA  . GLU A  1 425 ? 167.052 196.833 160.026 1.00 103.42 ? 425 GLU B CA  1 
ATOM   1651 C C   . GLU A  1 425 ? 167.802 195.947 161.014 1.00 104.16 ? 425 GLU B C   1 
ATOM   1652 O O   . GLU A  1 425 ? 167.569 196.001 162.225 1.00 99.78  ? 425 GLU B O   1 
ATOM   1653 C CB  . GLU A  1 425 ? 167.678 198.227 159.988 1.00 101.47 ? 425 GLU B CB  1 
ATOM   1654 C CG  . GLU A  1 425 ? 169.122 198.254 159.511 1.00 102.55 ? 425 GLU B CG  1 
ATOM   1655 C CD  . GLU A  1 425 ? 169.621 199.662 159.244 1.00 103.22 ? 425 GLU B CD  1 
ATOM   1656 O OE1 . GLU A  1 425 ? 168.838 200.617 159.426 1.00 103.80 ? 425 GLU B OE1 1 
ATOM   1657 O OE2 . GLU A  1 425 ? 170.798 199.812 158.854 1.00 102.34 ? 425 GLU B OE2 1 
ATOM   1658 N N   . SER A  1 426 ? 168.708 195.121 160.484 1.00 107.69 ? 426 SER B N   1 
ATOM   1659 C CA  . SER A  1 426 ? 169.497 194.240 161.339 1.00 106.62 ? 426 SER B CA  1 
ATOM   1660 C C   . SER A  1 426 ? 170.534 195.015 162.141 1.00 105.52 ? 426 SER B C   1 
ATOM   1661 O O   . SER A  1 426 ? 170.946 194.565 163.215 1.00 103.07 ? 426 SER B O   1 
ATOM   1662 C CB  . SER A  1 426 ? 170.177 193.162 160.496 1.00 106.05 ? 426 SER B CB  1 
ATOM   1663 O OG  . SER A  1 426 ? 171.124 193.730 159.609 1.00 105.85 ? 426 SER B OG  1 
ATOM   1664 N N   . LYS A  1 427 ? 170.968 196.167 161.638 1.00 108.60 ? 427 LYS B N   1 
ATOM   1665 C CA  . LYS A  1 427 ? 171.913 197.048 162.319 1.00 109.06 ? 427 LYS B CA  1 
ATOM   1666 C C   . LYS A  1 427 ? 171.335 198.453 162.414 1.00 110.72 ? 427 LYS B C   1 
ATOM   1667 O O   . LYS A  1 427 ? 171.981 199.449 162.080 1.00 108.34 ? 427 LYS B O   1 
ATOM   1668 C CB  . LYS A  1 427 ? 173.263 197.064 161.608 1.00 105.51 ? 427 LYS B CB  1 
ATOM   1669 C CG  . LYS A  1 427 ? 173.890 195.695 161.423 1.00 106.60 ? 427 LYS B CG  1 
ATOM   1670 C CD  . LYS A  1 427 ? 175.185 195.792 160.632 1.00 107.91 ? 427 LYS B CD  1 
ATOM   1671 C CE  . LYS A  1 427 ? 175.841 194.432 160.471 1.00 107.75 ? 427 LYS B CE  1 
ATOM   1672 N NZ  . LYS A  1 427 ? 177.131 194.526 159.733 1.00 106.79 ? 427 LYS B NZ  1 
ATOM   1673 N N   . GLY A  1 428 ? 170.082 198.539 162.867 1.00 108.04 ? 428 GLY B N   1 
ATOM   1674 C CA  . GLY A  1 428 ? 169.394 199.820 162.892 1.00 106.10 ? 428 GLY B CA  1 
ATOM   1675 C C   . GLY A  1 428 ? 170.051 200.838 163.805 1.00 105.37 ? 428 GLY B C   1 
ATOM   1676 O O   . GLY A  1 428 ? 170.142 202.020 163.466 1.00 105.79 ? 428 GLY B O   1 
ATOM   1677 N N   . LEU A  1 429 ? 170.523 200.396 164.972 1.00 94.14  ? 429 LEU B N   1 
ATOM   1678 C CA  . LEU A  1 429 ? 171.083 201.336 165.937 1.00 97.32  ? 429 LEU B CA  1 
ATOM   1679 C C   . LEU A  1 429 ? 172.439 201.888 165.513 1.00 100.54 ? 429 LEU B C   1 
ATOM   1680 O O   . LEU A  1 429 ? 173.013 202.701 166.246 1.00 103.58 ? 429 LEU B O   1 
ATOM   1681 C CB  . LEU A  1 429 ? 171.187 200.678 167.316 1.00 93.59  ? 429 LEU B CB  1 
ATOM   1682 C CG  . LEU A  1 429 ? 172.461 199.922 167.689 1.00 93.30  ? 429 LEU B CG  1 
ATOM   1683 C CD1 . LEU A  1 429 ? 172.423 199.536 169.160 1.00 89.58  ? 429 LEU B CD1 1 
ATOM   1684 C CD2 . LEU A  1 429 ? 172.642 198.700 166.813 1.00 97.17  ? 429 LEU B CD2 1 
ATOM   1685 N N   . LEU A  1 430 ? 172.958 201.481 164.357 1.00 103.29 ? 430 LEU B N   1 
ATOM   1686 C CA  . LEU A  1 430 ? 174.168 202.059 163.773 1.00 103.36 ? 430 LEU B CA  1 
ATOM   1687 C C   . LEU A  1 430 ? 173.855 202.466 162.339 1.00 103.02 ? 430 LEU B C   1 
ATOM   1688 O O   . LEU A  1 430 ? 174.259 201.795 161.382 1.00 100.57 ? 430 LEU B O   1 
ATOM   1689 C CB  . LEU A  1 430 ? 175.338 201.075 163.832 1.00 104.18 ? 430 LEU B CB  1 
ATOM   1690 C CG  . LEU A  1 430 ? 175.704 200.519 165.210 1.00 99.52  ? 430 LEU B CG  1 
ATOM   1691 C CD1 . LEU A  1 430 ? 176.814 199.486 165.098 1.00 99.15  ? 430 LEU B CD1 1 
ATOM   1692 C CD2 . LEU A  1 430 ? 176.107 201.637 166.155 1.00 97.18  ? 430 LEU B CD2 1 
ATOM   1693 N N   . PRO A  1 431 ? 173.122 203.564 162.156 1.00 117.49 ? 431 PRO B N   1 
ATOM   1694 C CA  . PRO A  1 431 ? 172.686 203.946 160.809 1.00 117.37 ? 431 PRO B CA  1 
ATOM   1695 C C   . PRO A  1 431 ? 173.837 204.433 159.942 1.00 116.44 ? 431 PRO B C   1 
ATOM   1696 O O   . PRO A  1 431 ? 174.852 204.935 160.430 1.00 116.09 ? 431 PRO B O   1 
ATOM   1697 C CB  . PRO A  1 431 ? 171.675 205.068 161.069 1.00 115.82 ? 431 PRO B CB  1 
ATOM   1698 C CG  . PRO A  1 431 ? 172.085 205.645 162.380 1.00 115.75 ? 431 PRO B CG  1 
ATOM   1699 C CD  . PRO A  1 431 ? 172.671 204.519 163.184 1.00 112.27 ? 431 PRO B CD  1 
ATOM   1700 N N   . ASN A  1 432 ? 173.659 204.280 158.627 1.00 127.67 ? 432 ASN B N   1 
ATOM   1701 C CA  . ASN A  1 432 ? 174.684 204.683 157.670 1.00 129.79 ? 432 ASN B CA  1 
ATOM   1702 C C   . ASN A  1 432 ? 174.747 206.193 157.482 1.00 128.36 ? 432 ASN B C   1 
ATOM   1703 O O   . ASN A  1 432 ? 175.830 206.733 157.225 1.00 127.42 ? 432 ASN B O   1 
ATOM   1704 C CB  . ASN A  1 432 ? 174.435 204.015 156.316 1.00 129.73 ? 432 ASN B CB  1 
ATOM   1705 C CG  . ASN A  1 432 ? 174.131 202.538 156.441 1.00 128.38 ? 432 ASN B CG  1 
ATOM   1706 O OD1 . ASN A  1 432 ? 173.024 202.148 156.815 1.00 128.46 ? 432 ASN B OD1 1 
ATOM   1707 N ND2 . ASN A  1 432 ? 175.111 201.706 156.115 1.00 127.44 ? 432 ASN B ND2 1 
ATOM   1708 N N   . ASN A  1 433 ? 173.614 206.882 157.594 1.00 138.35 ? 433 ASN B N   1 
ATOM   1709 C CA  . ASN A  1 433 ? 173.541 208.306 157.277 1.00 140.02 ? 433 ASN B CA  1 
ATOM   1710 C C   . ASN A  1 433 ? 174.416 209.100 158.238 1.00 140.26 ? 433 ASN B C   1 
ATOM   1711 O O   . ASN A  1 433 ? 174.152 209.140 159.445 1.00 140.00 ? 433 ASN B O   1 
ATOM   1712 C CB  . ASN A  1 433 ? 172.094 208.784 157.336 1.00 139.16 ? 433 ASN B CB  1 
ATOM   1713 C CG  . ASN A  1 433 ? 171.305 208.403 156.099 1.00 138.59 ? 433 ASN B CG  1 
ATOM   1714 O OD1 . ASN A  1 433 ? 171.655 207.459 155.391 1.00 138.66 ? 433 ASN B OD1 1 
ATOM   1715 N ND2 . ASN A  1 433 ? 170.232 209.138 155.832 1.00 137.66 ? 433 ASN B ND2 1 
ATOM   1716 N N   . SER A  1 434 ? 175.465 209.729 157.702 1.00 143.85 ? 434 SER B N   1 
ATOM   1717 C CA  . SER A  1 434 ? 176.318 210.582 158.522 1.00 143.69 ? 434 SER B CA  1 
ATOM   1718 C C   . SER A  1 434 ? 175.545 211.780 159.057 1.00 143.46 ? 434 SER B C   1 
ATOM   1719 O O   . SER A  1 434 ? 175.718 212.172 160.217 1.00 142.08 ? 434 SER B O   1 
ATOM   1720 C CB  . SER A  1 434 ? 177.531 211.042 157.713 1.00 142.21 ? 434 SER B CB  1 
ATOM   1721 O OG  . SER A  1 434 ? 177.138 211.555 156.453 1.00 141.46 ? 434 SER B OG  1 
ATOM   1722 N N   . GLU A  1 435 ? 174.691 212.375 158.227 1.00 147.40 ? 435 GLU B N   1 
ATOM   1723 C CA  . GLU A  1 435 ? 173.873 213.499 158.663 1.00 148.53 ? 435 GLU B CA  1 
ATOM   1724 C C   . GLU A  1 435 ? 172.838 213.018 159.672 1.00 147.76 ? 435 GLU B C   1 
ATOM   1725 O O   . GLU A  1 435 ? 172.021 212.142 159.367 1.00 145.76 ? 435 GLU B O   1 
ATOM   1726 C CB  . GLU A  1 435 ? 173.193 214.156 157.465 1.00 146.66 ? 435 GLU B CB  1 
ATOM   1727 C CG  . GLU A  1 435 ? 174.134 214.943 156.567 1.00 145.51 ? 435 GLU B CG  1 
ATOM   1728 C CD  . GLU A  1 435 ? 173.396 215.823 155.576 1.00 145.33 ? 435 GLU B CD  1 
ATOM   1729 O OE1 . GLU A  1 435 ? 172.229 215.512 155.257 1.00 147.46 ? 435 GLU B OE1 1 
ATOM   1730 O OE2 . GLU A  1 435 ? 173.982 216.825 155.116 1.00 144.77 ? 435 GLU B OE2 1 
ATOM   1731 N N   . GLU A  1 436 ? 172.872 213.590 160.876 1.00 137.89 ? 436 GLU B N   1 
ATOM   1732 C CA  . GLU A  1 436 ? 171.966 213.195 161.954 1.00 135.23 ? 436 GLU B CA  1 
ATOM   1733 C C   . GLU A  1 436 ? 170.651 213.963 161.814 1.00 134.71 ? 436 GLU B C   1 
ATOM   1734 O O   . GLU A  1 436 ? 170.332 214.881 162.573 1.00 132.49 ? 436 GLU B O   1 
ATOM   1735 C CB  . GLU A  1 436 ? 172.619 213.431 163.308 1.00 133.71 ? 436 GLU B CB  1 
ATOM   1736 C CG  . GLU A  1 436 ? 173.740 212.456 163.633 1.00 133.90 ? 436 GLU B CG  1 
ATOM   1737 C CD  . GLU A  1 436 ? 174.162 212.515 165.088 1.00 133.96 ? 436 GLU B CD  1 
ATOM   1738 O OE1 . GLU A  1 436 ? 174.598 213.595 165.539 1.00 132.71 ? 436 GLU B OE1 1 
ATOM   1739 O OE2 . GLU A  1 436 ? 174.055 211.482 165.781 1.00 134.68 ? 436 GLU B OE2 1 
ATOM   1740 N N   . SER A  1 437 ? 169.875 213.563 160.805 1.00 140.44 ? 437 SER B N   1 
ATOM   1741 C CA  . SER A  1 437 ? 168.590 214.199 160.543 1.00 139.50 ? 437 SER B CA  1 
ATOM   1742 C C   . SER A  1 437 ? 167.512 213.786 161.535 1.00 139.18 ? 437 SER B C   1 
ATOM   1743 O O   . SER A  1 437 ? 166.473 214.452 161.603 1.00 138.01 ? 437 SER B O   1 
ATOM   1744 C CB  . SER A  1 437 ? 168.128 213.881 159.120 1.00 138.25 ? 437 SER B CB  1 
ATOM   1745 O OG  . SER A  1 437 ? 167.939 212.487 158.944 1.00 135.92 ? 437 SER B OG  1 
ATOM   1746 N N   . GLY A  1 438 ? 167.725 212.712 162.293 1.00 129.94 ? 438 GLY B N   1 
ATOM   1747 C CA  . GLY A  1 438 ? 166.734 212.301 163.269 1.00 126.97 ? 438 GLY B CA  1 
ATOM   1748 C C   . GLY A  1 438 ? 166.554 213.339 164.359 1.00 126.08 ? 438 GLY B C   1 
ATOM   1749 O O   . GLY A  1 438 ? 167.510 213.955 164.831 1.00 125.64 ? 438 GLY B O   1 
ATOM   1750 N N   . ILE A  1 439 ? 165.295 213.529 164.767 1.00 119.15 ? 439 ILE B N   1 
ATOM   1751 C CA  . ILE A  1 439 ? 164.969 214.547 165.765 1.00 122.03 ? 439 ILE B CA  1 
ATOM   1752 C C   . ILE A  1 439 ? 165.295 214.113 167.182 1.00 118.90 ? 439 ILE B C   1 
ATOM   1753 O O   . ILE A  1 439 ? 165.045 214.877 168.124 1.00 119.27 ? 439 ILE B O   1 
ATOM   1754 C CB  . ILE A  1 439 ? 163.479 214.935 165.685 1.00 121.91 ? 439 ILE B CB  1 
ATOM   1755 C CG1 . ILE A  1 439 ? 162.597 213.690 165.796 1.00 120.11 ? 439 ILE B CG1 1 
ATOM   1756 C CG2 . ILE A  1 439 ? 163.192 215.683 164.392 1.00 118.35 ? 439 ILE B CG2 1 
ATOM   1757 C CD1 . ILE A  1 439 ? 161.116 213.991 165.782 1.00 118.74 ? 439 ILE B CD1 1 
ATOM   1758 N N   . CYS A  1 440 ? 165.841 212.911 167.369 1.00 106.54 ? 440 CYS B N   1 
ATOM   1759 C CA  . CYS A  1 440 ? 166.156 212.445 168.715 1.00 108.58 ? 440 CYS B CA  1 
ATOM   1760 C C   . CYS A  1 440 ? 167.338 213.205 169.300 1.00 106.35 ? 440 CYS B C   1 
ATOM   1761 O O   . CYS A  1 440 ? 167.293 213.649 170.453 1.00 103.64 ? 440 CYS B O   1 
ATOM   1762 C CB  . CYS A  1 440 ? 166.429 210.945 168.694 1.00 109.74 ? 440 CYS B CB  1 
ATOM   1763 S SG  . CYS A  1 440 ? 165.010 209.989 169.218 1.00 107.96 ? 440 CYS B SG  1 
ATOM   1764 N N   . HIS A  1 441 ? 168.411 213.359 168.523 1.00 118.04 ? 441 HIS B N   1 
ATOM   1765 C CA  . HIS A  1 441 ? 169.504 214.218 168.954 1.00 118.51 ? 441 HIS B CA  1 
ATOM   1766 C C   . HIS A  1 441 ? 169.121 215.688 168.882 1.00 120.05 ? 441 HIS B C   1 
ATOM   1767 O O   . HIS A  1 441 ? 169.817 216.528 169.462 1.00 119.39 ? 441 HIS B O   1 
ATOM   1768 C CB  . HIS A  1 441 ? 170.752 213.958 168.110 1.00 117.76 ? 441 HIS B CB  1 
ATOM   1769 C CG  . HIS A  1 441 ? 170.822 214.786 166.866 1.00 120.49 ? 441 HIS B CG  1 
ATOM   1770 N ND1 . HIS A  1 441 ? 171.446 216.015 166.823 1.00 123.05 ? 441 HIS B ND1 1 
ATOM   1771 C CD2 . HIS A  1 441 ? 170.343 214.565 165.620 1.00 119.66 ? 441 HIS B CD2 1 
ATOM   1772 C CE1 . HIS A  1 441 ? 171.349 216.514 165.604 1.00 121.63 ? 441 HIS B CE1 1 
ATOM   1773 N NE2 . HIS A  1 441 ? 170.684 215.654 164.854 1.00 121.29 ? 441 HIS B NE2 1 
ATOM   1774 N N   . LYS A  1 442 ? 168.036 216.014 168.182 1.00 121.09 ? 442 LYS B N   1 
ATOM   1775 C CA  . LYS A  1 442 ? 167.518 217.369 168.126 1.00 120.19 ? 442 LYS B CA  1 
ATOM   1776 C C   . LYS A  1 442 ? 166.529 217.594 169.268 1.00 120.66 ? 442 LYS B C   1 
ATOM   1777 O O   . LYS A  1 442 ? 166.247 216.701 170.070 1.00 118.59 ? 442 LYS B O   1 
ATOM   1778 C CB  . LYS A  1 442 ? 166.881 217.639 166.764 1.00 118.21 ? 442 LYS B CB  1 
ATOM   1779 C CG  . LYS A  1 442 ? 167.858 217.535 165.606 1.00 115.95 ? 442 LYS B CG  1 
ATOM   1780 C CD  . LYS A  1 442 ? 167.151 217.637 164.266 1.00 118.85 ? 442 LYS B CD  1 
ATOM   1781 C CE  . LYS A  1 442 ? 168.130 217.454 163.118 1.00 119.78 ? 442 LYS B CE  1 
ATOM   1782 N NZ  . LYS A  1 442 ? 167.440 217.407 161.800 1.00 119.80 ? 442 LYS B NZ  1 
ATOM   1783 N N   . TYR A  1 443 ? 165.995 218.811 169.346 1.00 114.23 ? 443 TYR B N   1 
ATOM   1784 C CA  . TYR A  1 443 ? 165.230 219.262 170.504 1.00 113.68 ? 443 TYR B CA  1 
ATOM   1785 C C   . TYR A  1 443 ? 163.981 220.010 170.062 1.00 112.62 ? 443 TYR B C   1 
ATOM   1786 O O   . TYR A  1 443 ? 163.611 221.035 170.644 1.00 112.45 ? 443 TYR B O   1 
ATOM   1787 C CB  . TYR A  1 443 ? 166.098 220.141 171.403 1.00 113.67 ? 443 TYR B CB  1 
ATOM   1788 C CG  . TYR A  1 443 ? 167.541 219.697 171.427 1.00 114.38 ? 443 TYR B CG  1 
ATOM   1789 C CD1 . TYR A  1 443 ? 167.918 218.525 172.071 1.00 111.44 ? 443 TYR B CD1 1 
ATOM   1790 C CD2 . TYR A  1 443 ? 168.515 220.408 170.740 1.00 114.42 ? 443 TYR B CD2 1 
ATOM   1791 C CE1 . TYR A  1 443 ? 169.234 218.106 172.076 1.00 114.99 ? 443 TYR B CE1 1 
ATOM   1792 C CE2 . TYR A  1 443 ? 169.831 219.991 170.734 1.00 113.99 ? 443 TYR B CE2 1 
ATOM   1793 C CZ  . TYR A  1 443 ? 170.187 218.843 171.405 1.00 117.12 ? 443 TYR B CZ  1 
ATOM   1794 O OH  . TYR A  1 443 ? 171.499 218.429 171.399 1.00 115.53 ? 443 TYR B OH  1 
ATOM   1795 N N   . THR A  1 444 ? 163.315 219.507 169.020 1.00 115.61 ? 444 THR B N   1 
ATOM   1796 C CA  . THR A  1 444 ? 162.132 220.188 168.502 1.00 119.55 ? 444 THR B CA  1 
ATOM   1797 C C   . THR A  1 444 ? 160.991 220.179 169.514 1.00 117.33 ? 444 THR B C   1 
ATOM   1798 O O   . THR A  1 444 ? 160.349 221.212 169.742 1.00 116.07 ? 444 THR B O   1 
ATOM   1799 C CB  . THR A  1 444 ? 161.689 219.542 167.188 1.00 117.73 ? 444 THR B CB  1 
ATOM   1800 O OG1 . THR A  1 444 ? 162.705 219.734 166.195 1.00 114.21 ? 444 THR B OG1 1 
ATOM   1801 C CG2 . THR A  1 444 ? 160.389 220.163 166.698 1.00 115.34 ? 444 THR B CG2 1 
ATOM   1802 N N   . TYR A  1 445 ? 160.725 219.027 170.134 1.00 108.22 ? 445 TYR B N   1 
ATOM   1803 C CA  . TYR A  1 445 ? 159.642 218.948 171.109 1.00 107.34 ? 445 TYR B CA  1 
ATOM   1804 C C   . TYR A  1 445 ? 159.975 219.702 172.390 1.00 110.01 ? 445 TYR B C   1 
ATOM   1805 O O   . TYR A  1 445 ? 159.087 220.308 172.999 1.00 110.78 ? 445 TYR B O   1 
ATOM   1806 C CB  . TYR A  1 445 ? 159.321 217.488 171.429 1.00 109.24 ? 445 TYR B CB  1 
ATOM   1807 C CG  . TYR A  1 445 ? 158.977 216.646 170.220 1.00 111.04 ? 445 TYR B CG  1 
ATOM   1808 C CD1 . TYR A  1 445 ? 157.950 217.015 169.362 1.00 111.13 ? 445 TYR B CD1 1 
ATOM   1809 C CD2 . TYR A  1 445 ? 159.674 215.477 169.944 1.00 109.00 ? 445 TYR B CD2 1 
ATOM   1810 C CE1 . TYR A  1 445 ? 157.631 216.245 168.258 1.00 112.17 ? 445 TYR B CE1 1 
ATOM   1811 C CE2 . TYR A  1 445 ? 159.362 214.701 168.845 1.00 107.30 ? 445 TYR B CE2 1 
ATOM   1812 C CZ  . TYR A  1 445 ? 158.341 215.090 168.005 1.00 111.31 ? 445 TYR B CZ  1 
ATOM   1813 O OH  . TYR A  1 445 ? 158.027 214.320 166.908 1.00 108.25 ? 445 TYR B OH  1 
ATOM   1814 N N   . GLY A  1 446 ? 161.237 219.681 172.810 1.00 92.70  ? 446 GLY B N   1 
ATOM   1815 C CA  . GLY A  1 446 ? 161.630 220.316 174.050 1.00 88.92  ? 446 GLY B CA  1 
ATOM   1816 C C   . GLY A  1 446 ? 161.469 219.468 175.291 1.00 85.51  ? 446 GLY B C   1 
ATOM   1817 O O   . GLY A  1 446 ? 161.668 219.978 176.398 1.00 83.71  ? 446 GLY B O   1 
ATOM   1818 N N   . VAL A  1 447 ? 161.111 218.190 175.145 1.00 78.52  ? 447 VAL B N   1 
ATOM   1819 C CA  . VAL A  1 447 ? 160.998 217.311 176.306 1.00 80.37  ? 447 VAL B CA  1 
ATOM   1820 C C   . VAL A  1 447 ? 162.373 217.005 176.887 1.00 84.87  ? 447 VAL B C   1 
ATOM   1821 O O   . VAL A  1 447 ? 162.499 216.685 178.078 1.00 88.98  ? 447 VAL B O   1 
ATOM   1822 C CB  . VAL A  1 447 ? 160.240 216.027 175.919 1.00 81.03  ? 447 VAL B CB  1 
ATOM   1823 C CG1 . VAL A  1 447 ? 161.127 215.101 175.096 1.00 76.81  ? 447 VAL B CG1 1 
ATOM   1824 C CG2 . VAL A  1 447 ? 159.714 215.321 177.159 1.00 79.70  ? 447 VAL B CG2 1 
ATOM   1825 N N   . ARG A  1 448 ? 163.421 217.102 176.065 1.00 86.68  ? 448 ARG B N   1 
ATOM   1826 C CA  . ARG A  1 448 ? 164.772 216.836 176.542 1.00 82.73  ? 448 ARG B CA  1 
ATOM   1827 C C   . ARG A  1 448 ? 165.168 217.832 177.624 1.00 83.79  ? 448 ARG B C   1 
ATOM   1828 O O   . ARG A  1 448 ? 165.785 217.461 178.630 1.00 84.27  ? 448 ARG B O   1 
ATOM   1829 C CB  . ARG A  1 448 ? 165.744 216.881 175.362 1.00 79.82  ? 448 ARG B CB  1 
ATOM   1830 C CG  . ARG A  1 448 ? 167.203 216.994 175.738 1.00 76.86  ? 448 ARG B CG  1 
ATOM   1831 C CD  . ARG A  1 448 ? 167.782 215.632 176.117 1.00 76.80  ? 448 ARG B CD  1 
ATOM   1832 N NE  . ARG A  1 448 ? 167.339 214.528 175.269 1.00 81.53  ? 448 ARG B NE  1 
ATOM   1833 C CZ  . ARG A  1 448 ? 167.551 214.434 173.962 1.00 88.87  ? 448 ARG B CZ  1 
ATOM   1834 N NH1 . ARG A  1 448 ? 168.251 215.344 173.305 1.00 89.42  ? 448 ARG B NH1 1 
ATOM   1835 N NH2 . ARG A  1 448 ? 167.061 213.390 173.300 1.00 87.64  ? 448 ARG B NH2 1 
ATOM   1836 N N   . ALA A  1 449 ? 164.796 219.102 177.445 1.00 70.64  ? 449 ALA B N   1 
ATOM   1837 C CA  . ALA A  1 449 ? 165.029 220.099 178.484 1.00 66.92  ? 449 ALA B CA  1 
ATOM   1838 C C   . ALA A  1 449 ? 164.264 219.761 179.758 1.00 66.66  ? 449 ALA B C   1 
ATOM   1839 O O   . ALA A  1 449 ? 164.777 219.953 180.866 1.00 63.96  ? 449 ALA B O   1 
ATOM   1840 C CB  . ALA A  1 449 ? 164.646 221.487 177.974 1.00 72.10  ? 449 ALA B CB  1 
ATOM   1841 N N   . ILE A  1 450 ? 163.036 219.253 179.626 1.00 63.84  ? 450 ILE B N   1 
ATOM   1842 C CA  . ILE A  1 450 ? 162.267 218.854 180.804 1.00 64.91  ? 450 ILE B CA  1 
ATOM   1843 C C   . ILE A  1 450 ? 163.007 217.771 181.581 1.00 70.65  ? 450 ILE B C   1 
ATOM   1844 O O   . ILE A  1 450 ? 163.206 217.875 182.802 1.00 73.70  ? 450 ILE B O   1 
ATOM   1845 C CB  . ILE A  1 450 ? 160.860 218.379 180.393 1.00 66.27  ? 450 ILE B CB  1 
ATOM   1846 C CG1 . ILE A  1 450 ? 159.983 219.556 179.963 1.00 61.33  ? 450 ILE B CG1 1 
ATOM   1847 C CG2 . ILE A  1 450 ? 160.208 217.599 181.525 1.00 67.67  ? 450 ILE B CG2 1 
ATOM   1848 C CD1 . ILE A  1 450 ? 159.122 220.119 181.074 1.00 67.51  ? 450 ILE B CD1 1 
ATOM   1849 N N   . VAL A  1 451 ? 163.434 216.716 180.882 1.00 59.37  ? 451 VAL B N   1 
ATOM   1850 C CA  . VAL A  1 451 ? 164.078 215.602 181.573 1.00 54.50  ? 451 VAL B CA  1 
ATOM   1851 C C   . VAL A  1 451 ? 165.455 216.000 182.083 1.00 60.20  ? 451 VAL B C   1 
ATOM   1852 O O   . VAL A  1 451 ? 165.995 215.357 182.990 1.00 64.70  ? 451 VAL B O   1 
ATOM   1853 C CB  . VAL A  1 451 ? 164.150 214.361 180.666 1.00 57.47  ? 451 VAL B CB  1 
ATOM   1854 C CG1 . VAL A  1 451 ? 162.845 214.179 179.921 1.00 59.05  ? 451 VAL B CG1 1 
ATOM   1855 C CG2 . VAL A  1 451 ? 165.310 214.476 179.695 1.00 61.61  ? 451 VAL B CG2 1 
ATOM   1856 N N   . GLN A  1 452 ? 166.057 217.044 181.507 1.00 63.55  ? 452 GLN B N   1 
ATOM   1857 C CA  . GLN A  1 452 ? 167.342 217.511 182.016 1.00 61.69  ? 452 GLN B CA  1 
ATOM   1858 C C   . GLN A  1 452 ? 167.181 218.403 183.245 1.00 62.21  ? 452 GLN B C   1 
ATOM   1859 O O   . GLN A  1 452 ? 168.046 218.396 184.128 1.00 56.64  ? 452 GLN B O   1 
ATOM   1860 C CB  . GLN A  1 452 ? 168.106 218.233 180.909 1.00 57.28  ? 452 GLN B CB  1 
ATOM   1861 C CG  . GLN A  1 452 ? 169.093 219.264 181.398 1.00 64.85  ? 452 GLN B CG  1 
ATOM   1862 C CD  . GLN A  1 452 ? 170.092 219.636 180.335 1.00 70.07  ? 452 GLN B CD  1 
ATOM   1863 O OE1 . GLN A  1 452 ? 171.230 219.985 180.635 1.00 71.87  ? 452 GLN B OE1 1 
ATOM   1864 N NE2 . GLN A  1 452 ? 169.679 219.545 179.079 1.00 66.11  ? 452 GLN B NE2 1 
ATOM   1865 N N   . CYS A  1 453 ? 166.089 219.165 183.331 1.00 60.89  ? 453 CYS B N   1 
ATOM   1866 C CA  . CYS A  1 453 ? 165.845 220.007 184.497 1.00 52.23  ? 453 CYS B CA  1 
ATOM   1867 C C   . CYS A  1 453 ? 165.175 219.269 185.647 1.00 59.11  ? 453 CYS B C   1 
ATOM   1868 O O   . CYS A  1 453 ? 165.122 219.812 186.756 1.00 61.82  ? 453 CYS B O   1 
ATOM   1869 C CB  . CYS A  1 453 ? 164.985 221.216 184.121 1.00 51.97  ? 453 CYS B CB  1 
ATOM   1870 S SG  . CYS A  1 453 ? 165.619 222.188 182.751 1.00 69.85  ? 453 CYS B SG  1 
ATOM   1871 N N   . ILE A  1 454 ? 164.656 218.061 185.411 1.00 58.94  ? 454 ILE B N   1 
ATOM   1872 C CA  . ILE A  1 454 ? 164.026 217.301 186.497 1.00 56.05  ? 454 ILE B CA  1 
ATOM   1873 C C   . ILE A  1 454 ? 164.938 217.142 187.712 1.00 58.18  ? 454 ILE B C   1 
ATOM   1874 O O   . ILE A  1 454 ? 164.470 217.368 188.841 1.00 56.49  ? 454 ILE B O   1 
ATOM   1875 C CB  . ILE A  1 454 ? 163.509 215.952 185.964 1.00 55.46  ? 454 ILE B CB  1 
ATOM   1876 C CG1 . ILE A  1 454 ? 162.105 216.121 185.382 1.00 63.66  ? 454 ILE B CG1 1 
ATOM   1877 C CG2 . ILE A  1 454 ? 163.515 214.892 187.061 1.00 47.62  ? 454 ILE B CG2 1 
ATOM   1878 C CD1 . ILE A  1 454 ? 161.420 214.819 185.032 1.00 62.75  ? 454 ILE B CD1 1 
ATOM   1879 N N   . PRO A  1 455 ? 166.217 216.761 187.573 1.00 52.01  ? 455 PRO B N   1 
ATOM   1880 C CA  . PRO A  1 455 ? 167.057 216.610 188.774 1.00 45.74  ? 455 PRO B CA  1 
ATOM   1881 C C   . PRO A  1 455 ? 167.221 217.887 189.579 1.00 53.28  ? 455 PRO B C   1 
ATOM   1882 O O   . PRO A  1 455 ? 167.300 217.823 190.811 1.00 49.47  ? 455 PRO B O   1 
ATOM   1883 C CB  . PRO A  1 455 ? 168.398 216.132 188.203 1.00 45.96  ? 455 PRO B CB  1 
ATOM   1884 C CG  . PRO A  1 455 ? 168.058 215.515 186.907 1.00 51.85  ? 455 PRO B CG  1 
ATOM   1885 C CD  . PRO A  1 455 ? 166.943 216.340 186.362 1.00 47.54  ? 455 PRO B CD  1 
ATOM   1886 N N   . ALA A  1 456 ? 167.289 219.046 188.922 1.00 54.43  ? 456 ALA B N   1 
ATOM   1887 C CA  . ALA A  1 456 ? 167.343 220.310 189.647 1.00 44.22  ? 456 ALA B CA  1 
ATOM   1888 C C   . ALA A  1 456 ? 165.976 220.714 190.178 1.00 42.02  ? 456 ALA B C   1 
ATOM   1889 O O   . ALA A  1 456 ? 165.886 221.331 191.246 1.00 55.91  ? 456 ALA B O   1 
ATOM   1890 C CB  . ALA A  1 456 ? 167.900 221.411 188.747 1.00 44.99  ? 456 ALA B CB  1 
ATOM   1891 N N   . TRP A  1 457 ? 164.913 220.380 189.446 1.00 38.23  ? 457 TRP B N   1 
ATOM   1892 C CA  . TRP A  1 457 ? 163.565 220.693 189.902 1.00 39.92  ? 457 TRP B CA  1 
ATOM   1893 C C   . TRP A  1 457 ? 163.244 219.968 191.200 1.00 45.74  ? 457 TRP B C   1 
ATOM   1894 O O   . TRP A  1 457 ? 162.587 220.527 192.086 1.00 52.72  ? 457 TRP B O   1 
ATOM   1895 C CB  . TRP A  1 457 ? 162.556 220.331 188.812 1.00 51.09  ? 457 TRP B CB  1 
ATOM   1896 C CG  . TRP A  1 457 ? 161.169 220.081 189.308 1.00 48.97  ? 457 TRP B CG  1 
ATOM   1897 C CD1 . TRP A  1 457 ? 160.652 218.894 189.735 1.00 51.18  ? 457 TRP B CD1 1 
ATOM   1898 C CD2 . TRP A  1 457 ? 160.112 221.039 189.410 1.00 43.67  ? 457 TRP B CD2 1 
ATOM   1899 N NE1 . TRP A  1 457 ? 159.341 219.056 190.107 1.00 49.28  ? 457 TRP B NE1 1 
ATOM   1900 C CE2 . TRP A  1 457 ? 158.985 220.365 189.916 1.00 45.87  ? 457 TRP B CE2 1 
ATOM   1901 C CE3 . TRP A  1 457 ? 160.010 222.404 189.127 1.00 45.12  ? 457 TRP B CE3 1 
ATOM   1902 C CZ2 . TRP A  1 457 ? 157.773 221.006 190.145 1.00 50.65  ? 457 TRP B CZ2 1 
ATOM   1903 C CZ3 . TRP A  1 457 ? 158.806 223.039 189.355 1.00 52.34  ? 457 TRP B CZ3 1 
ATOM   1904 C CH2 . TRP A  1 457 ? 157.703 222.341 189.858 1.00 52.20  ? 457 TRP B CH2 1 
ATOM   1905 N N   . LEU A  1 458 ? 163.694 218.717 191.327 1.00 52.08  ? 458 LEU B N   1 
ATOM   1906 C CA  . LEU A  1 458 ? 163.451 217.972 192.558 1.00 49.15  ? 458 LEU B CA  1 
ATOM   1907 C C   . LEU A  1 458 ? 164.093 218.661 193.755 1.00 51.88  ? 458 LEU B C   1 
ATOM   1908 O O   . LEU A  1 458 ? 163.463 218.801 194.810 1.00 58.10  ? 458 LEU B O   1 
ATOM   1909 C CB  . LEU A  1 458 ? 163.974 216.543 192.419 1.00 38.19  ? 458 LEU B CB  1 
ATOM   1910 C CG  . LEU A  1 458 ? 163.243 215.663 191.407 1.00 47.89  ? 458 LEU B CG  1 
ATOM   1911 C CD1 . LEU A  1 458 ? 163.995 214.364 191.183 1.00 53.77  ? 458 LEU B CD1 1 
ATOM   1912 C CD2 . LEU A  1 458 ? 161.824 215.392 191.869 1.00 51.24  ? 458 LEU B CD2 1 
ATOM   1913 N N   . ARG A  1 459 ? 165.338 219.116 193.606 1.00 45.82  ? 459 ARG B N   1 
ATOM   1914 C CA  . ARG A  1 459 ? 166.003 219.807 194.705 1.00 45.53  ? 459 ARG B CA  1 
ATOM   1915 C C   . ARG A  1 459 ? 165.352 221.154 194.991 1.00 47.81  ? 459 ARG B C   1 
ATOM   1916 O O   . ARG A  1 459 ? 165.250 221.565 196.152 1.00 50.62  ? 459 ARG B O   1 
ATOM   1917 C CB  . ARG A  1 459 ? 167.488 219.985 194.400 1.00 36.02  ? 459 ARG B CB  1 
ATOM   1918 C CG  . ARG A  1 459 ? 168.371 218.959 195.072 1.00 33.60  ? 459 ARG B CG  1 
ATOM   1919 C CD  . ARG A  1 459 ? 167.980 218.785 196.527 1.00 35.42  ? 459 ARG B CD  1 
ATOM   1920 N NE  . ARG A  1 459 ? 168.572 219.791 197.396 1.00 38.67  ? 459 ARG B NE  1 
ATOM   1921 C CZ  . ARG A  1 459 ? 168.214 219.987 198.657 1.00 43.98  ? 459 ARG B CZ  1 
ATOM   1922 N NH1 . ARG A  1 459 ? 167.252 219.276 199.219 1.00 53.25  ? 459 ARG B NH1 1 
ATOM   1923 N NH2 . ARG A  1 459 ? 168.842 220.913 199.373 1.00 43.06  ? 459 ARG B NH2 1 
ATOM   1924 N N   . PHE A  1 460 ? 164.913 221.860 193.949 1.00 45.09  ? 460 PHE B N   1 
ATOM   1925 C CA  . PHE A  1 460 ? 164.229 223.132 194.157 1.00 42.17  ? 460 PHE B CA  1 
ATOM   1926 C C   . PHE A  1 460 ? 162.956 222.937 194.971 1.00 44.08  ? 460 PHE B C   1 
ATOM   1927 O O   . PHE A  1 460 ? 162.695 223.673 195.933 1.00 60.42  ? 460 PHE B O   1 
ATOM   1928 C CB  . PHE A  1 460 ? 163.924 223.777 192.805 1.00 45.27  ? 460 PHE B CB  1 
ATOM   1929 C CG  . PHE A  1 460 ? 163.003 224.956 192.883 1.00 43.79  ? 460 PHE B CG  1 
ATOM   1930 C CD1 . PHE A  1 460 ? 163.342 226.070 193.627 1.00 49.57  ? 460 PHE B CD1 1 
ATOM   1931 C CD2 . PHE A  1 460 ? 161.802 224.956 192.197 1.00 46.42  ? 460 PHE B CD2 1 
ATOM   1932 C CE1 . PHE A  1 460 ? 162.495 227.156 193.695 1.00 51.04  ? 460 PHE B CE1 1 
ATOM   1933 C CE2 . PHE A  1 460 ? 160.953 226.039 192.260 1.00 45.78  ? 460 PHE B CE2 1 
ATOM   1934 C CZ  . PHE A  1 460 ? 161.300 227.140 193.008 1.00 51.31  ? 460 PHE B CZ  1 
ATOM   1935 N N   . ILE A  1 461 ? 162.166 221.922 194.618 1.00 36.78  ? 461 ILE B N   1 
ATOM   1936 C CA  . ILE A  1 461 ? 160.923 221.669 195.337 1.00 43.39  ? 461 ILE B CA  1 
ATOM   1937 C C   . ILE A  1 461 ? 161.209 221.186 196.754 1.00 43.03  ? 461 ILE B C   1 
ATOM   1938 O O   . ILE A  1 461 ? 160.494 221.539 197.697 1.00 43.28  ? 461 ILE B O   1 
ATOM   1939 C CB  . ILE A  1 461 ? 160.046 220.674 194.559 1.00 43.78  ? 461 ILE B CB  1 
ATOM   1940 C CG1 . ILE A  1 461 ? 159.708 221.241 193.182 1.00 45.51  ? 461 ILE B CG1 1 
ATOM   1941 C CG2 . ILE A  1 461 ? 158.770 220.394 195.315 1.00 39.99  ? 461 ILE B CG2 1 
ATOM   1942 C CD1 . ILE A  1 461 ? 158.790 222.440 193.231 1.00 47.69  ? 461 ILE B CD1 1 
ATOM   1943 N N   . GLN A  1 462 ? 162.258 220.378 196.932 1.00 48.25  ? 462 GLN B N   1 
ATOM   1944 C CA  . GLN A  1 462 ? 162.625 219.946 198.277 1.00 49.12  ? 462 GLN B CA  1 
ATOM   1945 C C   . GLN A  1 462 ? 163.032 221.123 199.150 1.00 49.61  ? 462 GLN B C   1 
ATOM   1946 O O   . GLN A  1 462 ? 162.659 221.188 200.323 1.00 49.53  ? 462 GLN B O   1 
ATOM   1947 C CB  . GLN A  1 462 ? 163.748 218.915 198.218 1.00 38.59  ? 462 GLN B CB  1 
ATOM   1948 C CG  . GLN A  1 462 ? 163.266 217.530 197.890 1.00 42.25  ? 462 GLN B CG  1 
ATOM   1949 C CD  . GLN A  1 462 ? 164.372 216.511 197.893 1.00 50.61  ? 462 GLN B CD  1 
ATOM   1950 O OE1 . GLN A  1 462 ? 164.636 215.871 196.880 1.00 61.50  ? 462 GLN B OE1 1 
ATOM   1951 N NE2 . GLN A  1 462 ? 165.031 216.355 199.032 1.00 50.22  ? 462 GLN B NE2 1 
ATOM   1952 N N   . CYS A  1 463 ? 163.807 222.059 198.601 1.00 49.70  ? 463 CYS B N   1 
ATOM   1953 C CA  . CYS A  1 463 ? 164.203 223.230 199.376 1.00 46.55  ? 463 CYS B CA  1 
ATOM   1954 C C   . CYS A  1 463 ? 162.998 224.098 199.717 1.00 58.82  ? 463 CYS B C   1 
ATOM   1955 O O   . CYS A  1 463 ? 162.896 224.623 200.835 1.00 65.55  ? 463 CYS B O   1 
ATOM   1956 C CB  . CYS A  1 463 ? 165.250 224.032 198.608 1.00 44.77  ? 463 CYS B CB  1 
ATOM   1957 S SG  . CYS A  1 463 ? 166.937 223.465 198.890 1.00 62.32  ? 463 CYS B SG  1 
ATOM   1958 N N   . LEU A  1 464 ? 162.071 224.260 198.768 1.00 53.05  ? 464 LEU B N   1 
ATOM   1959 C CA  . LEU A  1 464 ? 160.853 225.005 199.065 1.00 38.01  ? 464 LEU B CA  1 
ATOM   1960 C C   . LEU A  1 464 ? 160.053 224.328 200.171 1.00 48.74  ? 464 LEU B C   1 
ATOM   1961 O O   . LEU A  1 464 ? 159.519 224.999 201.062 1.00 53.03  ? 464 LEU B O   1 
ATOM   1962 C CB  . LEU A  1 464 ? 160.004 225.156 197.805 1.00 36.82  ? 464 LEU B CB  1 
ATOM   1963 C CG  . LEU A  1 464 ? 160.451 226.233 196.817 1.00 39.72  ? 464 LEU B CG  1 
ATOM   1964 C CD1 . LEU A  1 464 ? 159.336 226.538 195.836 1.00 52.02  ? 464 LEU B CD1 1 
ATOM   1965 C CD2 . LEU A  1 464 ? 160.890 227.489 197.547 1.00 46.01  ? 464 LEU B CD2 1 
ATOM   1966 N N   . ARG A  1 465 ? 159.962 222.996 200.132 1.00 53.21  ? 465 ARG B N   1 
ATOM   1967 C CA  . ARG A  1 465 ? 159.255 222.268 201.181 1.00 54.51  ? 465 ARG B CA  1 
ATOM   1968 C C   . ARG A  1 465 ? 159.957 222.418 202.524 1.00 54.49  ? 465 ARG B C   1 
ATOM   1969 O O   . ARG A  1 465 ? 159.302 222.540 203.565 1.00 56.89  ? 465 ARG B O   1 
ATOM   1970 C CB  . ARG A  1 465 ? 159.127 220.794 200.801 1.00 48.31  ? 465 ARG B CB  1 
ATOM   1971 C CG  . ARG A  1 465 ? 158.842 219.871 201.972 1.00 47.60  ? 465 ARG B CG  1 
ATOM   1972 C CD  . ARG A  1 465 ? 157.412 220.032 202.455 1.00 55.88  ? 465 ARG B CD  1 
ATOM   1973 N NE  . ARG A  1 465 ? 157.249 219.612 203.842 1.00 60.25  ? 465 ARG B NE  1 
ATOM   1974 C CZ  . ARG A  1 465 ? 156.701 218.465 204.216 1.00 59.61  ? 465 ARG B CZ  1 
ATOM   1975 N NH1 . ARG A  1 465 ? 156.245 217.595 203.330 1.00 54.93  ? 465 ARG B NH1 1 
ATOM   1976 N NH2 . ARG A  1 465 ? 156.605 218.184 205.512 1.00 57.83  ? 465 ARG B NH2 1 
ATOM   1977 N N   . ARG A  1 466 ? 161.291 222.407 202.520 1.00 58.66  ? 466 ARG B N   1 
ATOM   1978 C CA  . ARG A  1 466 ? 162.035 222.619 203.757 1.00 60.07  ? 466 ARG B CA  1 
ATOM   1979 C C   . ARG A  1 466 ? 161.725 223.985 204.348 1.00 57.08  ? 466 ARG B C   1 
ATOM   1980 O O   . ARG A  1 466 ? 161.497 224.109 205.557 1.00 61.78  ? 466 ARG B O   1 
ATOM   1981 C CB  . ARG A  1 466 ? 163.537 222.485 203.511 1.00 54.56  ? 466 ARG B CB  1 
ATOM   1982 C CG  . ARG A  1 466 ? 163.995 221.114 203.078 1.00 56.14  ? 466 ARG B CG  1 
ATOM   1983 C CD  . ARG A  1 466 ? 165.464 220.901 203.392 1.00 55.93  ? 466 ARG B CD  1 
ATOM   1984 N NE  . ARG A  1 466 ? 165.687 220.711 204.820 1.00 55.20  ? 466 ARG B NE  1 
ATOM   1985 C CZ  . ARG A  1 466 ? 166.694 221.244 205.498 1.00 60.26  ? 466 ARG B CZ  1 
ATOM   1986 N NH1 . ARG A  1 466 ? 167.588 222.021 204.910 1.00 63.48  ? 466 ARG B NH1 1 
ATOM   1987 N NH2 . ARG A  1 466 ? 166.805 220.992 206.798 1.00 55.57  ? 466 ARG B NH2 1 
ATOM   1988 N N   . TYR A  1 467 ? 161.711 225.024 203.509 1.00 57.49  ? 467 TYR B N   1 
ATOM   1989 C CA  . TYR A  1 467 ? 161.374 226.355 204.004 1.00 61.07  ? 467 TYR B CA  1 
ATOM   1990 C C   . TYR A  1 467 ? 159.948 226.395 204.536 1.00 60.73  ? 467 TYR B C   1 
ATOM   1991 O O   . TYR A  1 467 ? 159.686 226.964 205.601 1.00 62.74  ? 467 TYR B O   1 
ATOM   1992 C CB  . TYR A  1 467 ? 161.555 227.401 202.906 1.00 62.37  ? 467 TYR B CB  1 
ATOM   1993 C CG  . TYR A  1 467 ? 160.794 228.679 203.184 1.00 65.63  ? 467 TYR B CG  1 
ATOM   1994 C CD1 . TYR A  1 467 ? 161.109 229.474 204.279 1.00 62.33  ? 467 TYR B CD1 1 
ATOM   1995 C CD2 . TYR A  1 467 ? 159.761 229.090 202.354 1.00 66.21  ? 467 TYR B CD2 1 
ATOM   1996 C CE1 . TYR A  1 467 ? 160.419 230.639 204.539 1.00 61.39  ? 467 TYR B CE1 1 
ATOM   1997 C CE2 . TYR A  1 467 ? 159.065 230.256 202.607 1.00 66.92  ? 467 TYR B CE2 1 
ATOM   1998 C CZ  . TYR A  1 467 ? 159.398 231.026 203.700 1.00 68.48  ? 467 TYR B CZ  1 
ATOM   1999 O OH  . TYR A  1 467 ? 158.707 232.187 203.956 1.00 68.59  ? 467 TYR B OH  1 
ATOM   2000 N N   . ARG A  1 468 ? 159.010 225.790 203.805 1.00 55.51  ? 468 ARG B N   1 
ATOM   2001 C CA  . ARG A  1 468 ? 157.621 225.771 204.249 1.00 60.51  ? 468 ARG B CA  1 
ATOM   2002 C C   . ARG A  1 468 ? 157.474 225.052 205.583 1.00 62.96  ? 468 ARG B C   1 
ATOM   2003 O O   . ARG A  1 468 ? 156.631 225.429 206.405 1.00 65.34  ? 468 ARG B O   1 
ATOM   2004 C CB  . ARG A  1 468 ? 156.749 225.123 203.173 1.00 59.64  ? 468 ARG B CB  1 
ATOM   2005 C CG  . ARG A  1 468 ? 155.483 224.450 203.672 1.00 60.36  ? 468 ARG B CG  1 
ATOM   2006 C CD  . ARG A  1 468 ? 154.900 223.546 202.597 1.00 63.14  ? 468 ARG B CD  1 
ATOM   2007 N NE  . ARG A  1 468 ? 155.064 224.120 201.266 1.00 67.04  ? 468 ARG B NE  1 
ATOM   2008 C CZ  . ARG A  1 468 ? 155.029 223.424 200.138 1.00 61.73  ? 468 ARG B CZ  1 
ATOM   2009 N NH1 . ARG A  1 468 ? 154.823 222.117 200.139 1.00 57.57  ? 468 ARG B NH1 1 
ATOM   2010 N NH2 . ARG A  1 468 ? 155.204 224.054 198.980 1.00 56.69  ? 468 ARG B NH2 1 
ATOM   2011 N N   . ASP A  1 469 ? 158.294 224.029 205.822 1.00 68.04  ? 469 ASP B N   1 
ATOM   2012 C CA  . ASP A  1 469 ? 158.235 223.300 207.083 1.00 70.66  ? 469 ASP B CA  1 
ATOM   2013 C C   . ASP A  1 469 ? 158.886 224.076 208.222 1.00 71.05  ? 469 ASP B C   1 
ATOM   2014 O O   . ASP A  1 469 ? 158.406 224.024 209.360 1.00 70.52  ? 469 ASP B O   1 
ATOM   2015 C CB  . ASP A  1 469 ? 158.900 221.933 206.926 1.00 66.09  ? 469 ASP B CB  1 
ATOM   2016 C CG  . ASP A  1 469 ? 158.236 220.865 207.766 1.00 73.87  ? 469 ASP B CG  1 
ATOM   2017 O OD1 . ASP A  1 469 ? 157.974 221.125 208.960 1.00 72.91  ? 469 ASP B OD1 1 
ATOM   2018 O OD2 . ASP A  1 469 ? 157.974 219.766 207.233 1.00 75.46  ? 469 ASP B OD2 1 
ATOM   2019 N N   . THR A  1 470 ? 159.975 224.796 207.946 1.00 72.44  ? 470 THR B N   1 
ATOM   2020 C CA  . THR A  1 470 ? 160.716 225.473 209.003 1.00 71.46  ? 470 THR B CA  1 
ATOM   2021 C C   . THR A  1 470 ? 160.467 226.974 209.065 1.00 70.63  ? 470 THR B C   1 
ATOM   2022 O O   . THR A  1 470 ? 160.796 227.593 210.083 1.00 71.38  ? 470 THR B O   1 
ATOM   2023 C CB  . THR A  1 470 ? 162.222 225.235 208.843 1.00 67.71  ? 470 THR B CB  1 
ATOM   2024 O OG1 . THR A  1 470 ? 162.899 225.647 210.036 1.00 67.87  ? 470 THR B OG1 1 
ATOM   2025 C CG2 . THR A  1 470 ? 162.762 226.036 207.677 1.00 67.39  ? 470 THR B CG2 1 
ATOM   2026 N N   . LYS A  1 471 ? 159.902 227.568 208.012 1.00 74.46  ? 471 LYS B N   1 
ATOM   2027 C CA  . LYS A  1 471 ? 159.630 229.007 207.962 1.00 77.21  ? 471 LYS B CA  1 
ATOM   2028 C C   . LYS A  1 471 ? 160.898 229.825 208.206 1.00 78.51  ? 471 LYS B C   1 
ATOM   2029 O O   . LYS A  1 471 ? 160.876 230.854 208.883 1.00 79.49  ? 471 LYS B O   1 
ATOM   2030 C CB  . LYS A  1 471 ? 158.527 229.392 208.950 1.00 71.39  ? 471 LYS B CB  1 
ATOM   2031 C CG  . LYS A  1 471 ? 157.204 228.693 208.676 1.00 73.11  ? 471 LYS B CG  1 
ATOM   2032 C CD  . LYS A  1 471 ? 156.243 228.825 209.843 1.00 79.37  ? 471 LYS B CD  1 
ATOM   2033 C CE  . LYS A  1 471 ? 154.992 227.991 209.616 1.00 78.23  ? 471 LYS B CE  1 
ATOM   2034 N NZ  . LYS A  1 471 ? 154.059 228.054 210.774 1.00 76.83  ? 471 LYS B NZ  1 
ATOM   2035 N N   . ARG A  1 472 ? 162.014 229.359 207.646 1.00 77.55  ? 472 ARG B N   1 
ATOM   2036 C CA  . ARG A  1 472 ? 163.295 230.057 207.707 1.00 74.66  ? 472 ARG B CA  1 
ATOM   2037 C C   . ARG A  1 472 ? 163.696 230.428 206.286 1.00 72.35  ? 472 ARG B C   1 
ATOM   2038 O O   . ARG A  1 472 ? 163.946 229.545 205.459 1.00 65.56  ? 472 ARG B O   1 
ATOM   2039 C CB  . ARG A  1 472 ? 164.368 229.191 208.366 1.00 70.14  ? 472 ARG B CB  1 
ATOM   2040 C CG  . ARG A  1 472 ? 164.327 229.179 209.883 1.00 69.49  ? 472 ARG B CG  1 
ATOM   2041 C CD  . ARG A  1 472 ? 165.493 228.384 210.451 1.00 69.22  ? 472 ARG B CD  1 
ATOM   2042 N NE  . ARG A  1 472 ? 166.778 228.887 209.980 1.00 72.22  ? 472 ARG B NE  1 
ATOM   2043 C CZ  . ARG A  1 472 ? 167.884 228.916 210.710 1.00 73.10  ? 472 ARG B CZ  1 
ATOM   2044 N NH1 . ARG A  1 472 ? 167.901 228.475 211.958 1.00 71.48  ? 472 ARG B NH1 1 
ATOM   2045 N NH2 . ARG A  1 472 ? 169.002 229.399 210.176 1.00 69.59  ? 472 ARG B NH2 1 
ATOM   2046 N N   . ALA A  1 473 ? 163.763 231.731 206.007 1.00 69.74  ? 473 ALA B N   1 
ATOM   2047 C CA  . ALA A  1 473 ? 164.144 232.179 204.671 1.00 66.56  ? 473 ALA B CA  1 
ATOM   2048 C C   . ALA A  1 473 ? 165.540 231.693 204.309 1.00 66.49  ? 473 ALA B C   1 
ATOM   2049 O O   . ALA A  1 473 ? 165.790 231.284 203.170 1.00 67.41  ? 473 ALA B O   1 
ATOM   2050 C CB  . ALA A  1 473 ? 164.064 233.702 204.584 1.00 65.84  ? 473 ALA B CB  1 
ATOM   2051 N N   . PHE A  1 474 ? 166.458 231.731 205.264 1.00 67.46  ? 474 PHE B N   1 
ATOM   2052 C CA  . PHE A  1 474 ? 167.817 231.230 205.155 1.00 66.05  ? 474 PHE B CA  1 
ATOM   2053 C C   . PHE A  1 474 ? 167.962 229.945 205.959 1.00 63.09  ? 474 PHE B C   1 
ATOM   2054 O O   . PHE A  1 474 ? 167.409 229.838 207.059 1.00 64.96  ? 474 PHE B O   1 
ATOM   2055 C CB  . PHE A  1 474 ? 168.812 232.270 205.670 1.00 66.36  ? 474 PHE B CB  1 
ATOM   2056 C CG  . PHE A  1 474 ? 170.238 231.984 205.302 1.00 63.12  ? 474 PHE B CG  1 
ATOM   2057 C CD1 . PHE A  1 474 ? 170.700 232.242 204.025 1.00 67.03  ? 474 PHE B CD1 1 
ATOM   2058 C CD2 . PHE A  1 474 ? 171.118 231.465 206.235 1.00 62.79  ? 474 PHE B CD2 1 
ATOM   2059 C CE1 . PHE A  1 474 ? 172.009 231.982 203.680 1.00 68.93  ? 474 PHE B CE1 1 
ATOM   2060 C CE2 . PHE A  1 474 ? 172.430 231.204 205.896 1.00 68.47  ? 474 PHE B CE2 1 
ATOM   2061 C CZ  . PHE A  1 474 ? 172.876 231.466 204.617 1.00 67.58  ? 474 PHE B CZ  1 
ATOM   2062 N N   . PRO A  1 475 ? 168.690 228.943 205.454 1.00 61.85  ? 475 PRO B N   1 
ATOM   2063 C CA  . PRO A  1 475 ? 169.388 228.885 204.169 1.00 60.85  ? 475 PRO B CA  1 
ATOM   2064 C C   . PRO A  1 475 ? 168.619 228.135 203.091 1.00 58.42  ? 475 PRO B C   1 
ATOM   2065 O O   . PRO A  1 475 ? 169.219 227.419 202.297 1.00 58.29  ? 475 PRO B O   1 
ATOM   2066 C CB  . PRO A  1 475 ? 170.671 228.146 204.539 1.00 62.08  ? 475 PRO B CB  1 
ATOM   2067 C CG  . PRO A  1 475 ? 170.201 227.135 205.555 1.00 58.96  ? 475 PRO B CG  1 
ATOM   2068 C CD  . PRO A  1 475 ? 169.059 227.798 206.306 1.00 63.98  ? 475 PRO B CD  1 
ATOM   2069 N N   . HIS A  1 476 ? 167.298 228.271 203.027 1.00 60.96  ? 476 HIS B N   1 
ATOM   2070 C CA  . HIS A  1 476 ? 166.493 227.460 202.123 1.00 57.44  ? 476 HIS B CA  1 
ATOM   2071 C C   . HIS A  1 476 ? 166.107 228.182 200.840 1.00 56.66  ? 476 HIS B C   1 
ATOM   2072 O O   . HIS A  1 476 ? 166.138 227.574 199.769 1.00 53.36  ? 476 HIS B O   1 
ATOM   2073 C CB  . HIS A  1 476 ? 165.235 226.968 202.843 1.00 54.82  ? 476 HIS B CB  1 
ATOM   2074 C CG  . HIS A  1 476 ? 165.524 226.117 204.041 1.00 55.75  ? 476 HIS B CG  1 
ATOM   2075 N ND1 . HIS A  1 476 ? 164.574 225.311 204.627 1.00 59.34  ? 476 HIS B ND1 1 
ATOM   2076 C CD2 . HIS A  1 476 ? 166.661 225.935 204.752 1.00 54.35  ? 476 HIS B CD2 1 
ATOM   2077 C CE1 . HIS A  1 476 ? 165.111 224.675 205.653 1.00 59.25  ? 476 HIS B CE1 1 
ATOM   2078 N NE2 . HIS A  1 476 ? 166.376 225.038 205.752 1.00 53.85  ? 476 HIS B NE2 1 
ATOM   2079 N N   . LEU A  1 477 ? 165.758 229.469 200.902 1.00 52.56  ? 477 LEU B N   1 
ATOM   2080 C CA  . LEU A  1 477 ? 165.442 230.190 199.672 1.00 49.54  ? 477 LEU B CA  1 
ATOM   2081 C C   . LEU A  1 477 ? 166.692 230.450 198.842 1.00 57.32  ? 477 LEU B C   1 
ATOM   2082 O O   . LEU A  1 477 ? 166.632 230.446 197.607 1.00 66.87  ? 477 LEU B O   1 
ATOM   2083 C CB  . LEU A  1 477 ? 164.720 231.500 199.983 1.00 55.96  ? 477 LEU B CB  1 
ATOM   2084 C CG  . LEU A  1 477 ? 163.218 231.404 200.264 1.00 57.58  ? 477 LEU B CG  1 
ATOM   2085 C CD1 . LEU A  1 477 ? 162.520 230.628 199.157 1.00 54.92  ? 477 LEU B CD1 1 
ATOM   2086 C CD2 . LEU A  1 477 ? 162.935 230.780 201.610 1.00 54.68  ? 477 LEU B CD2 1 
ATOM   2087 N N   . VAL A  1 478 ? 167.834 230.676 199.494 1.00 51.47  ? 478 VAL B N   1 
ATOM   2088 C CA  . VAL A  1 478 ? 169.085 230.816 198.754 1.00 50.22  ? 478 VAL B CA  1 
ATOM   2089 C C   . VAL A  1 478 ? 169.390 229.531 197.996 1.00 54.30  ? 478 VAL B C   1 
ATOM   2090 O O   . VAL A  1 478 ? 169.760 229.557 196.816 1.00 57.67  ? 478 VAL B O   1 
ATOM   2091 C CB  . VAL A  1 478 ? 170.232 231.192 199.710 1.00 49.75  ? 478 VAL B CB  1 
ATOM   2092 C CG1 . VAL A  1 478 ? 171.445 231.659 198.928 1.00 49.76  ? 478 VAL B CG1 1 
ATOM   2093 C CG2 . VAL A  1 478 ? 169.782 232.254 200.690 1.00 49.61  ? 478 VAL B CG2 1 
ATOM   2094 N N   . ASN A  1 479 ? 169.225 228.387 198.662 1.00 56.24  ? 479 ASN B N   1 
ATOM   2095 C CA  . ASN A  1 479 ? 169.430 227.097 198.013 1.00 53.48  ? 479 ASN B CA  1 
ATOM   2096 C C   . ASN A  1 479 ? 168.423 226.870 196.891 1.00 59.45  ? 479 ASN B C   1 
ATOM   2097 O O   . ASN A  1 479 ? 168.767 226.322 195.835 1.00 69.55  ? 479 ASN B O   1 
ATOM   2098 C CB  . ASN A  1 479 ? 169.339 225.986 199.057 1.00 44.03  ? 479 ASN B CB  1 
ATOM   2099 C CG  . ASN A  1 479 ? 170.258 224.828 198.757 1.00 45.77  ? 479 ASN B CG  1 
ATOM   2100 O OD1 . ASN A  1 479 ? 171.367 225.012 198.261 1.00 55.11  ? 479 ASN B OD1 1 
ATOM   2101 N ND2 . ASN A  1 479 ? 169.803 223.624 199.065 1.00 47.82  ? 479 ASN B ND2 1 
ATOM   2102 N N   . ALA A  1 480 ? 167.168 227.271 197.108 1.00 51.89  ? 480 ALA B N   1 
ATOM   2103 C CA  . ALA A  1 480 ? 166.154 227.128 196.071 1.00 51.97  ? 480 ALA B CA  1 
ATOM   2104 C C   . ALA A  1 480 ? 166.510 227.947 194.839 1.00 44.18  ? 480 ALA B C   1 
ATOM   2105 O O   . ALA A  1 480 ? 166.345 227.482 193.709 1.00 46.62  ? 480 ALA B O   1 
ATOM   2106 C CB  . ALA A  1 480 ? 164.786 227.538 196.614 1.00 49.39  ? 480 ALA B CB  1 
ATOM   2107 N N   . GLY A  1 481 ? 167.008 229.167 195.037 1.00 43.17  ? 481 GLY B N   1 
ATOM   2108 C CA  . GLY A  1 481 ? 167.476 229.950 193.906 1.00 54.17  ? 481 GLY B CA  1 
ATOM   2109 C C   . GLY A  1 481 ? 168.687 229.333 193.233 1.00 54.50  ? 481 GLY B C   1 
ATOM   2110 O O   . GLY A  1 481 ? 168.820 229.378 192.005 1.00 59.62  ? 481 GLY B O   1 
ATOM   2111 N N   . LYS A  1 482 ? 169.588 228.749 194.027 1.00 53.70  ? 482 LYS B N   1 
ATOM   2112 C CA  . LYS A  1 482 ? 170.751 228.071 193.463 1.00 53.70  ? 482 LYS B CA  1 
ATOM   2113 C C   . LYS A  1 482 ? 170.325 226.946 192.533 1.00 57.92  ? 482 LYS B C   1 
ATOM   2114 O O   . LYS A  1 482 ? 170.867 226.789 191.433 1.00 57.81  ? 482 LYS B O   1 
ATOM   2115 C CB  . LYS A  1 482 ? 171.634 227.527 194.585 1.00 52.58  ? 482 LYS B CB  1 
ATOM   2116 C CG  . LYS A  1 482 ? 172.404 226.275 194.214 1.00 47.13  ? 482 LYS B CG  1 
ATOM   2117 C CD  . LYS A  1 482 ? 173.352 225.879 195.322 1.00 58.41  ? 482 LYS B CD  1 
ATOM   2118 C CE  . LYS A  1 482 ? 174.072 224.584 195.005 1.00 63.90  ? 482 LYS B CE  1 
ATOM   2119 N NZ  . LYS A  1 482 ? 173.181 223.406 195.152 1.00 57.32  ? 482 LYS B NZ  1 
ATOM   2120 N N   . TYR A  1 483 ? 169.346 226.150 192.962 1.00 54.43  ? 483 TYR B N   1 
ATOM   2121 C CA  . TYR A  1 483 ? 168.845 225.076 192.114 1.00 41.44  ? 483 TYR B CA  1 
ATOM   2122 C C   . TYR A  1 483 ? 167.968 225.594 190.984 1.00 51.22  ? 483 TYR B C   1 
ATOM   2123 O O   . TYR A  1 483 ? 167.835 224.918 189.960 1.00 57.58  ? 483 TYR B O   1 
ATOM   2124 C CB  . TYR A  1 483 ? 168.081 224.057 192.956 1.00 34.76  ? 483 TYR B CB  1 
ATOM   2125 C CG  . TYR A  1 483 ? 168.985 223.200 193.805 1.00 39.44  ? 483 TYR B CG  1 
ATOM   2126 C CD1 . TYR A  1 483 ? 169.886 222.324 193.223 1.00 46.86  ? 483 TYR B CD1 1 
ATOM   2127 C CD2 . TYR A  1 483 ? 168.943 223.271 195.187 1.00 42.18  ? 483 TYR B CD2 1 
ATOM   2128 C CE1 . TYR A  1 483 ? 170.717 221.541 193.994 1.00 48.53  ? 483 TYR B CE1 1 
ATOM   2129 C CE2 . TYR A  1 483 ? 169.770 222.492 195.966 1.00 47.98  ? 483 TYR B CE2 1 
ATOM   2130 C CZ  . TYR A  1 483 ? 170.654 221.628 195.364 1.00 52.87  ? 483 TYR B CZ  1 
ATOM   2131 O OH  . TYR A  1 483 ? 171.482 220.848 196.135 1.00 57.82  ? 483 TYR B OH  1 
ATOM   2132 N N   . SER A  1 484 ? 167.369 226.775 191.147 1.00 59.17  ? 484 SER B N   1 
ATOM   2133 C CA  . SER A  1 484 ? 166.554 227.373 190.100 1.00 57.78  ? 484 SER B CA  1 
ATOM   2134 C C   . SER A  1 484 ? 167.382 227.995 188.989 1.00 54.20  ? 484 SER B C   1 
ATOM   2135 O O   . SER A  1 484 ? 166.860 228.198 187.888 1.00 51.82  ? 484 SER B O   1 
ATOM   2136 C CB  . SER A  1 484 ? 165.629 228.435 190.694 1.00 60.07  ? 484 SER B CB  1 
ATOM   2137 O OG  . SER A  1 484 ? 165.131 229.291 189.683 1.00 63.65  ? 484 SER B OG  1 
ATOM   2138 N N   . THR A  1 485 ? 168.646 228.327 189.260 1.00 56.65  ? 485 THR B N   1 
ATOM   2139 C CA  . THR A  1 485 ? 169.513 228.824 188.194 1.00 56.21  ? 485 THR B CA  1 
ATOM   2140 C C   . THR A  1 485 ? 169.580 227.846 187.027 1.00 60.43  ? 485 THR B C   1 
ATOM   2141 O O   . THR A  1 485 ? 169.715 228.266 185.871 1.00 65.06  ? 485 THR B O   1 
ATOM   2142 C CB  . THR A  1 485 ? 170.921 229.089 188.724 1.00 56.66  ? 485 THR B CB  1 
ATOM   2143 O OG1 . THR A  1 485 ? 171.480 227.870 189.228 1.00 66.77  ? 485 THR B OG1 1 
ATOM   2144 C CG2 . THR A  1 485 ? 170.895 230.126 189.827 1.00 62.05  ? 485 THR B CG2 1 
ATOM   2145 N N   . THR A  1 486 ? 169.481 226.544 187.310 1.00 55.12  ? 486 THR B N   1 
ATOM   2146 C CA  . THR A  1 486 ? 169.496 225.541 186.249 1.00 56.69  ? 486 THR B CA  1 
ATOM   2147 C C   . THR A  1 486 ? 168.293 225.697 185.327 1.00 59.86  ? 486 THR B C   1 
ATOM   2148 O O   . THR A  1 486 ? 168.393 225.457 184.116 1.00 64.36  ? 486 THR B O   1 
ATOM   2149 C CB  . THR A  1 486 ? 169.533 224.140 186.861 1.00 56.72  ? 486 THR B CB  1 
ATOM   2150 O OG1 . THR A  1 486 ? 170.801 223.931 187.494 1.00 66.95  ? 486 THR B OG1 1 
ATOM   2151 C CG2 . THR A  1 486 ? 169.333 223.073 185.797 1.00 56.12  ? 486 THR B CG2 1 
ATOM   2152 N N   . PHE A  1 487 ? 167.143 226.094 185.880 1.00 59.50  ? 487 PHE B N   1 
ATOM   2153 C CA  . PHE A  1 487 ? 165.965 226.314 185.047 1.00 59.46  ? 487 PHE B CA  1 
ATOM   2154 C C   . PHE A  1 487 ? 166.252 227.341 183.963 1.00 57.83  ? 487 PHE B C   1 
ATOM   2155 O O   . PHE A  1 487 ? 166.044 227.077 182.777 1.00 52.40  ? 487 PHE B O   1 
ATOM   2156 C CB  . PHE A  1 487 ? 164.775 226.767 185.895 1.00 60.12  ? 487 PHE B CB  1 
ATOM   2157 C CG  . PHE A  1 487 ? 164.450 225.855 187.036 1.00 56.51  ? 487 PHE B CG  1 
ATOM   2158 C CD1 . PHE A  1 487 ? 164.679 224.495 186.946 1.00 57.63  ? 487 PHE B CD1 1 
ATOM   2159 C CD2 . PHE A  1 487 ? 163.894 226.360 188.196 1.00 58.57  ? 487 PHE B CD2 1 
ATOM   2160 C CE1 . PHE A  1 487 ? 164.374 223.662 187.998 1.00 58.27  ? 487 PHE B CE1 1 
ATOM   2161 C CE2 . PHE A  1 487 ? 163.587 225.533 189.251 1.00 55.98  ? 487 PHE B CE2 1 
ATOM   2162 C CZ  . PHE A  1 487 ? 163.827 224.182 189.152 1.00 56.13  ? 487 PHE B CZ  1 
ATOM   2163 N N   . PHE A  1 488 ? 166.752 228.515 184.355 1.00 64.09  ? 488 PHE B N   1 
ATOM   2164 C CA  . PHE A  1 488 ? 167.047 229.559 183.377 1.00 65.39  ? 488 PHE B CA  1 
ATOM   2165 C C   . PHE A  1 488 ? 168.179 229.141 182.447 1.00 68.24  ? 488 PHE B C   1 
ATOM   2166 O O   . PHE A  1 488 ? 168.130 229.412 181.240 1.00 76.39  ? 488 PHE B O   1 
ATOM   2167 C CB  . PHE A  1 488 ? 167.381 230.866 184.094 1.00 70.36  ? 488 PHE B CB  1 
ATOM   2168 C CG  . PHE A  1 488 ? 166.326 231.309 185.067 1.00 71.36  ? 488 PHE B CG  1 
ATOM   2169 C CD1 . PHE A  1 488 ? 164.983 231.164 184.764 1.00 69.22  ? 488 PHE B CD1 1 
ATOM   2170 C CD2 . PHE A  1 488 ? 166.674 231.873 186.282 1.00 72.68  ? 488 PHE B CD2 1 
ATOM   2171 C CE1 . PHE A  1 488 ? 164.009 231.567 185.654 1.00 70.90  ? 488 PHE B CE1 1 
ATOM   2172 C CE2 . PHE A  1 488 ? 165.704 232.279 187.177 1.00 69.92  ? 488 PHE B CE2 1 
ATOM   2173 C CZ  . PHE A  1 488 ? 164.370 232.126 186.862 1.00 70.80  ? 488 PHE B CZ  1 
ATOM   2174 N N   . MET A  1 489 ? 169.204 228.481 182.995 1.00 64.67  ? 489 MET B N   1 
ATOM   2175 C CA  . MET A  1 489 ? 170.263 227.901 182.175 1.00 68.07  ? 489 MET B CA  1 
ATOM   2176 C C   . MET A  1 489 ? 169.698 227.107 181.004 1.00 75.53  ? 489 MET B C   1 
ATOM   2177 O O   . MET A  1 489 ? 169.902 227.463 179.836 1.00 77.21  ? 489 MET B O   1 
ATOM   2178 C CB  . MET A  1 489 ? 171.138 227.004 183.048 1.00 71.71  ? 489 MET B CB  1 
ATOM   2179 C CG  . MET A  1 489 ? 172.429 226.556 182.412 1.00 74.61  ? 489 MET B CG  1 
ATOM   2180 S SD  . MET A  1 489 ? 173.741 227.770 182.267 1.00 85.97  ? 489 MET B SD  1 
ATOM   2181 C CE  . MET A  1 489 ? 175.146 226.660 182.251 1.00 74.74  ? 489 MET B CE  1 
ATOM   2182 N N   . VAL A  1 490 ? 168.972 226.031 181.303 1.00 72.98  ? 490 VAL B N   1 
ATOM   2183 C CA  . VAL A  1 490 ? 168.493 225.142 180.251 1.00 66.43  ? 490 VAL B CA  1 
ATOM   2184 C C   . VAL A  1 490 ? 167.429 225.826 179.401 1.00 69.79  ? 490 VAL B C   1 
ATOM   2185 O O   . VAL A  1 490 ? 167.312 225.553 178.200 1.00 70.39  ? 490 VAL B O   1 
ATOM   2186 C CB  . VAL A  1 490 ? 167.982 223.826 180.859 1.00 63.24  ? 490 VAL B CB  1 
ATOM   2187 C CG1 . VAL A  1 490 ? 167.699 222.817 179.764 1.00 65.00  ? 490 VAL B CG1 1 
ATOM   2188 C CG2 . VAL A  1 490 ? 168.996 223.277 181.848 1.00 59.58  ? 490 VAL B CG2 1 
ATOM   2189 N N   . THR A  1 491 ? 166.671 226.742 180.000 1.00 72.77  ? 491 THR B N   1 
ATOM   2190 C CA  . THR A  1 491 ? 165.653 227.468 179.249 1.00 75.37  ? 491 THR B CA  1 
ATOM   2191 C C   . THR A  1 491 ? 166.314 228.190 178.118 1.00 74.85  ? 491 THR B C   1 
ATOM   2192 O O   . THR A  1 491 ? 166.011 227.947 176.957 1.00 79.63  ? 491 THR B O   1 
ATOM   2193 C CB  . THR A  1 491 ? 164.942 228.541 180.086 1.00 77.90  ? 491 THR B CB  1 
ATOM   2194 O OG1 . THR A  1 491 ? 164.298 227.944 181.212 1.00 78.94  ? 491 THR B OG1 1 
ATOM   2195 C CG2 . THR A  1 491 ? 163.883 229.244 179.265 1.00 78.47  ? 491 THR B CG2 1 
ATOM   2196 N N   . PHE A  1 492 ? 167.240 229.071 178.453 1.00 76.95  ? 492 PHE B N   1 
ATOM   2197 C CA  . PHE A  1 492 ? 167.873 229.882 177.424 1.00 83.31  ? 492 PHE B CA  1 
ATOM   2198 C C   . PHE A  1 492 ? 168.767 229.045 176.521 1.00 83.78  ? 492 PHE B C   1 
ATOM   2199 O O   . PHE A  1 492 ? 168.961 229.399 175.356 1.00 87.65  ? 492 PHE B O   1 
ATOM   2200 C CB  . PHE A  1 492 ? 168.626 231.040 178.069 1.00 82.48  ? 492 PHE B CB  1 
ATOM   2201 C CG  . PHE A  1 492 ? 167.734 231.951 178.857 1.00 81.16  ? 492 PHE B CG  1 
ATOM   2202 C CD1 . PHE A  1 492 ? 166.571 232.442 178.291 1.00 80.96  ? 492 PHE B CD1 1 
ATOM   2203 C CD2 . PHE A  1 492 ? 168.027 232.285 180.163 1.00 84.60  ? 492 PHE B CD2 1 
ATOM   2204 C CE1 . PHE A  1 492 ? 165.731 233.268 179.004 1.00 82.66  ? 492 PHE B CE1 1 
ATOM   2205 C CE2 . PHE A  1 492 ? 167.184 233.106 180.882 1.00 82.24  ? 492 PHE B CE2 1 
ATOM   2206 C CZ  . PHE A  1 492 ? 166.039 233.601 180.301 1.00 83.99  ? 492 PHE B CZ  1 
ATOM   2207 N N   . ALA A  1 493 ? 169.263 227.905 177.008 1.00 83.60  ? 493 ALA B N   1 
ATOM   2208 C CA  . ALA A  1 493 ? 169.983 226.989 176.128 1.00 84.15  ? 493 ALA B CA  1 
ATOM   2209 C C   . ALA A  1 493 ? 169.077 226.458 175.023 1.00 84.24  ? 493 ALA B C   1 
ATOM   2210 O O   . ALA A  1 493 ? 169.427 226.508 173.836 1.00 84.18  ? 493 ALA B O   1 
ATOM   2211 C CB  . ALA A  1 493 ? 170.558 225.835 176.944 1.00 87.49  ? 493 ALA B CB  1 
ATOM   2212 N N   . ALA A  1 494 ? 167.905 225.944 175.396 1.00 84.40  ? 494 ALA B N   1 
ATOM   2213 C CA  . ALA A  1 494 ? 166.980 225.410 174.402 1.00 85.97  ? 494 ALA B CA  1 
ATOM   2214 C C   . ALA A  1 494 ? 166.424 226.515 173.513 1.00 92.52  ? 494 ALA B C   1 
ATOM   2215 O O   . ALA A  1 494 ? 166.187 226.297 172.318 1.00 95.86  ? 494 ALA B O   1 
ATOM   2216 C CB  . ALA A  1 494 ? 165.851 224.649 175.092 1.00 82.99  ? 494 ALA B CB  1 
ATOM   2217 N N   . LEU A  1 495 ? 166.200 227.705 174.078 1.00 94.65  ? 495 LEU B N   1 
ATOM   2218 C CA  . LEU A  1 495 ? 165.760 228.827 173.257 1.00 91.36  ? 495 LEU B CA  1 
ATOM   2219 C C   . LEU A  1 495 ? 166.819 229.203 172.231 1.00 93.75  ? 495 LEU B C   1 
ATOM   2220 O O   . LEU A  1 495 ? 166.492 229.494 171.078 1.00 95.63  ? 495 LEU B O   1 
ATOM   2221 C CB  . LEU A  1 495 ? 165.408 230.026 174.136 1.00 92.13  ? 495 LEU B CB  1 
ATOM   2222 C CG  . LEU A  1 495 ? 164.159 229.854 175.000 1.00 95.39  ? 495 LEU B CG  1 
ATOM   2223 C CD1 . LEU A  1 495 ? 164.123 230.890 176.112 1.00 93.87  ? 495 LEU B CD1 1 
ATOM   2224 C CD2 . LEU A  1 495 ? 162.905 229.928 174.145 1.00 96.05  ? 495 LEU B CD2 1 
ATOM   2225 N N   . TYR A  1 496 ? 168.094 229.194 172.627 1.00 99.14  ? 496 TYR B N   1 
ATOM   2226 C CA  . TYR A  1 496 ? 169.167 229.431 171.669 1.00 98.62  ? 496 TYR B CA  1 
ATOM   2227 C C   . TYR A  1 496 ? 169.193 228.350 170.599 1.00 97.62  ? 496 TYR B C   1 
ATOM   2228 O O   . TYR A  1 496 ? 169.403 228.644 169.417 1.00 100.59 ? 496 TYR B O   1 
ATOM   2229 C CB  . TYR A  1 496 ? 170.510 229.519 172.400 1.00 99.50  ? 496 TYR B CB  1 
ATOM   2230 C CG  . TYR A  1 496 ? 171.732 229.370 171.515 1.00 99.20  ? 496 TYR B CG  1 
ATOM   2231 C CD1 . TYR A  1 496 ? 172.440 230.484 171.094 1.00 99.15  ? 496 TYR B CD1 1 
ATOM   2232 C CD2 . TYR A  1 496 ? 172.216 228.116 171.155 1.00 100.01 ? 496 TYR B CD2 1 
ATOM   2233 C CE1 . TYR A  1 496 ? 173.559 230.360 170.298 1.00 99.14  ? 496 TYR B CE1 1 
ATOM   2234 C CE2 . TYR A  1 496 ? 173.336 227.984 170.360 1.00 100.09 ? 496 TYR B CE2 1 
ATOM   2235 C CZ  . TYR A  1 496 ? 174.006 229.110 169.938 1.00 101.37 ? 496 TYR B CZ  1 
ATOM   2236 O OH  . TYR A  1 496 ? 175.126 228.989 169.149 1.00 106.35 ? 496 TYR B OH  1 
ATOM   2237 N N   . SER A  1 497 ? 168.999 227.091 170.997 1.00 100.32 ? 497 SER B N   1 
ATOM   2238 C CA  . SER A  1 497 ? 168.963 226.005 170.020 1.00 103.13 ? 497 SER B CA  1 
ATOM   2239 C C   . SER A  1 497 ? 167.876 226.243 168.979 1.00 105.43 ? 497 SER B C   1 
ATOM   2240 O O   . SER A  1 497 ? 168.134 226.210 167.770 1.00 105.50 ? 497 SER B O   1 
ATOM   2241 C CB  . SER A  1 497 ? 168.735 224.670 170.726 1.00 101.80 ? 497 SER B CB  1 
ATOM   2242 O OG  . SER A  1 497 ? 167.355 224.444 170.953 1.00 101.54 ? 497 SER B OG  1 
ATOM   2243 N N   . THR A  1 498 ? 166.651 226.504 169.441 1.00 104.92 ? 498 THR B N   1 
ATOM   2244 C CA  . THR A  1 498 ? 165.538 226.718 168.521 1.00 104.99 ? 498 THR B CA  1 
ATOM   2245 C C   . THR A  1 498 ? 165.751 227.966 167.674 1.00 104.87 ? 498 THR B C   1 
ATOM   2246 O O   . THR A  1 498 ? 165.415 227.983 166.484 1.00 104.13 ? 498 THR B O   1 
ATOM   2247 C CB  . THR A  1 498 ? 164.227 226.818 169.298 1.00 106.29 ? 498 THR B CB  1 
ATOM   2248 O OG1 . THR A  1 498 ? 164.305 227.904 170.231 1.00 102.12 ? 498 THR B OG1 1 
ATOM   2249 C CG2 . THR A  1 498 ? 163.954 225.524 170.051 1.00 104.40 ? 498 THR B CG2 1 
ATOM   2250 N N   . HIS A  1 499 ? 166.307 229.020 168.270 1.00 109.49 ? 499 HIS B N   1 
ATOM   2251 C CA  . HIS A  1 499 ? 166.476 230.287 167.576 1.00 110.24 ? 499 HIS B CA  1 
ATOM   2252 C C   . HIS A  1 499 ? 167.553 230.208 166.502 1.00 111.92 ? 499 HIS B C   1 
ATOM   2253 O O   . HIS A  1 499 ? 167.397 230.802 165.430 1.00 112.21 ? 499 HIS B O   1 
ATOM   2254 C CB  . HIS A  1 499 ? 166.814 231.378 168.595 1.00 108.23 ? 499 HIS B CB  1 
ATOM   2255 C CG  . HIS A  1 499 ? 166.149 232.690 168.326 1.00 108.75 ? 499 HIS B CG  1 
ATOM   2256 N ND1 . HIS A  1 499 ? 164.818 232.917 168.603 1.00 108.23 ? 499 HIS B ND1 1 
ATOM   2257 C CD2 . HIS A  1 499 ? 166.631 233.851 167.826 1.00 109.09 ? 499 HIS B CD2 1 
ATOM   2258 C CE1 . HIS A  1 499 ? 164.507 234.158 168.275 1.00 107.32 ? 499 HIS B CE1 1 
ATOM   2259 N NE2 . HIS A  1 499 ? 165.590 234.747 167.803 1.00 108.85 ? 499 HIS B NE2 1 
ATOM   2260 N N   . LYS A  1 500 ? 168.644 229.487 166.766 1.00 113.36 ? 500 LYS B N   1 
ATOM   2261 C CA  . LYS A  1 500 ? 169.715 229.339 165.791 1.00 112.27 ? 500 LYS B CA  1 
ATOM   2262 C C   . LYS A  1 500 ? 169.407 228.298 164.725 1.00 112.93 ? 500 LYS B C   1 
ATOM   2263 O O   . LYS A  1 500 ? 169.787 228.486 163.563 1.00 112.71 ? 500 LYS B O   1 
ATOM   2264 C CB  . LYS A  1 500 ? 171.026 228.974 166.493 1.00 109.34 ? 500 LYS B CB  1 
ATOM   2265 C CG  . LYS A  1 500 ? 172.255 229.116 165.607 1.00 110.98 ? 500 LYS B CG  1 
ATOM   2266 C CD  . LYS A  1 500 ? 173.499 229.420 166.421 1.00 111.76 ? 500 LYS B CD  1 
ATOM   2267 C CE  . LYS A  1 500 ? 174.518 230.193 165.601 1.00 109.98 ? 500 LYS B CE  1 
ATOM   2268 N NZ  . LYS A  1 500 ? 175.722 230.549 166.399 1.00 110.13 ? 500 LYS B NZ  1 
ATOM   2269 N N   . GLU A  1 501 ? 168.725 227.210 165.080 1.00 121.76 ? 501 GLU B N   1 
ATOM   2270 C CA  . GLU A  1 501 ? 168.405 226.186 164.095 1.00 121.49 ? 501 GLU B CA  1 
ATOM   2271 C C   . GLU A  1 501 ? 167.242 226.574 163.192 1.00 123.47 ? 501 GLU B C   1 
ATOM   2272 O O   . GLU A  1 501 ? 166.966 225.858 162.223 1.00 124.13 ? 501 GLU B O   1 
ATOM   2273 C CB  . GLU A  1 501 ? 168.102 224.856 164.791 1.00 120.98 ? 501 GLU B CB  1 
ATOM   2274 C CG  . GLU A  1 501 ? 169.289 224.269 165.541 1.00 123.70 ? 501 GLU B CG  1 
ATOM   2275 C CD  . GLU A  1 501 ? 168.991 222.904 166.130 1.00 125.81 ? 501 GLU B CD  1 
ATOM   2276 O OE1 . GLU A  1 501 ? 167.860 222.409 165.946 1.00 124.02 ? 501 GLU B OE1 1 
ATOM   2277 O OE2 . GLU A  1 501 ? 169.889 222.327 166.780 1.00 127.01 ? 501 GLU B OE2 1 
ATOM   2278 N N   . ARG A  1 502 ? 166.559 227.682 163.478 1.00 124.12 ? 502 ARG B N   1 
ATOM   2279 C CA  . ARG A  1 502 ? 165.481 228.173 162.633 1.00 122.69 ? 502 ARG B CA  1 
ATOM   2280 C C   . ARG A  1 502 ? 165.837 229.464 161.910 1.00 120.47 ? 502 ARG B C   1 
ATOM   2281 O O   . ARG A  1 502 ? 165.052 229.927 161.074 1.00 119.99 ? 502 ARG B O   1 
ATOM   2282 C CB  . ARG A  1 502 ? 164.208 228.373 163.463 1.00 119.96 ? 502 ARG B CB  1 
ATOM   2283 C CG  . ARG A  1 502 ? 163.577 227.073 163.937 1.00 121.08 ? 502 ARG B CG  1 
ATOM   2284 C CD  . ARG A  1 502 ? 162.534 227.314 165.015 1.00 121.68 ? 502 ARG B CD  1 
ATOM   2285 N NE  . ARG A  1 502 ? 162.163 226.078 165.693 1.00 123.43 ? 502 ARG B NE  1 
ATOM   2286 C CZ  . ARG A  1 502 ? 161.341 226.010 166.731 1.00 123.03 ? 502 ARG B CZ  1 
ATOM   2287 N NH1 . ARG A  1 502 ? 160.783 227.095 167.244 1.00 121.60 ? 502 ARG B NH1 1 
ATOM   2288 N NH2 . ARG A  1 502 ? 161.073 224.824 167.271 1.00 119.94 ? 502 ARG B NH2 1 
ATOM   2289 N N   . GLY A  1 503 ? 166.992 230.056 162.203 1.00 118.52 ? 503 GLY B N   1 
ATOM   2290 C CA  . GLY A  1 503 ? 167.454 231.224 161.479 1.00 117.65 ? 503 GLY B CA  1 
ATOM   2291 C C   . GLY A  1 503 ? 166.715 232.506 161.803 1.00 119.73 ? 503 GLY B C   1 
ATOM   2292 O O   . GLY A  1 503 ? 166.027 233.064 160.943 1.00 120.31 ? 503 GLY B O   1 
ATOM   2293 N N   . HIS A  1 504 ? 166.847 232.985 163.035 1.00 116.89 ? 504 HIS B N   1 
ATOM   2294 C CA  . HIS A  1 504 ? 166.247 234.241 163.458 1.00 117.62 ? 504 HIS B CA  1 
ATOM   2295 C C   . HIS A  1 504 ? 167.340 235.263 163.751 1.00 116.86 ? 504 HIS B C   1 
ATOM   2296 O O   . HIS A  1 504 ? 168.534 234.952 163.753 1.00 115.16 ? 504 HIS B O   1 
ATOM   2297 C CB  . HIS A  1 504 ? 165.352 234.043 164.687 1.00 117.98 ? 504 HIS B CB  1 
ATOM   2298 C CG  . HIS A  1 504 ? 164.281 233.015 164.496 1.00 119.98 ? 504 HIS B CG  1 
ATOM   2299 N ND1 . HIS A  1 504 ? 164.036 232.016 165.414 1.00 118.02 ? 504 HIS B ND1 1 
ATOM   2300 C CD2 . HIS A  1 504 ? 163.389 232.831 163.494 1.00 120.02 ? 504 HIS B CD2 1 
ATOM   2301 C CE1 . HIS A  1 504 ? 163.040 231.262 164.986 1.00 117.25 ? 504 HIS B CE1 1 
ATOM   2302 N NE2 . HIS A  1 504 ? 162.630 231.735 163.823 1.00 119.27 ? 504 HIS B NE2 1 
ATOM   2303 N N   . SER A  1 505 ? 166.914 236.500 164.002 1.00 118.40 ? 505 SER B N   1 
ATOM   2304 C CA  . SER A  1 505 ? 167.835 237.617 164.171 1.00 119.96 ? 505 SER B CA  1 
ATOM   2305 C C   . SER A  1 505 ? 168.225 237.879 165.620 1.00 119.05 ? 505 SER B C   1 
ATOM   2306 O O   . SER A  1 505 ? 169.067 238.749 165.867 1.00 118.94 ? 505 SER B O   1 
ATOM   2307 C CB  . SER A  1 505 ? 167.228 238.892 163.575 1.00 117.59 ? 505 SER B CB  1 
ATOM   2308 O OG  . SER A  1 505 ? 166.015 239.230 164.224 1.00 113.95 ? 505 SER B OG  1 
ATOM   2309 N N   . ASP A  1 506 ? 167.642 237.162 166.583 1.00 114.25 ? 506 ASP B N   1 
ATOM   2310 C CA  . ASP A  1 506 ? 167.965 237.348 167.993 1.00 113.75 ? 506 ASP B CA  1 
ATOM   2311 C C   . ASP A  1 506 ? 168.730 236.161 168.570 1.00 113.59 ? 506 ASP B C   1 
ATOM   2312 O O   . ASP A  1 506 ? 168.744 235.968 169.791 1.00 111.46 ? 506 ASP B O   1 
ATOM   2313 C CB  . ASP A  1 506 ? 166.693 237.606 168.801 1.00 115.25 ? 506 ASP B CB  1 
ATOM   2314 C CG  . ASP A  1 506 ? 166.011 238.903 168.415 1.00 116.88 ? 506 ASP B CG  1 
ATOM   2315 O OD1 . ASP A  1 506 ? 166.553 239.628 167.554 1.00 116.19 ? 506 ASP B OD1 1 
ATOM   2316 O OD2 . ASP A  1 506 ? 164.931 239.197 168.970 1.00 116.00 ? 506 ASP B OD2 1 
ATOM   2317 N N   . THR A  1 507 ? 169.358 235.356 167.710 1.00 110.15 ? 507 THR B N   1 
ATOM   2318 C CA  . THR A  1 507 ? 170.140 234.223 168.192 1.00 107.57 ? 507 THR B CA  1 
ATOM   2319 C C   . THR A  1 507 ? 171.318 234.691 169.035 1.00 108.46 ? 507 THR B C   1 
ATOM   2320 O O   . THR A  1 507 ? 171.620 234.097 170.076 1.00 111.37 ? 507 THR B O   1 
ATOM   2321 C CB  . THR A  1 507 ? 170.620 233.378 167.011 1.00 108.30 ? 507 THR B CB  1 
ATOM   2322 O OG1 . THR A  1 507 ? 169.535 232.580 166.522 1.00 108.69 ? 507 THR B OG1 1 
ATOM   2323 C CG2 . THR A  1 507 ? 171.762 232.465 167.427 1.00 105.65 ? 507 THR B CG2 1 
ATOM   2324 N N   . MET A  1 508 ? 171.992 235.760 168.605 1.00 113.03 ? 508 MET B N   1 
ATOM   2325 C CA  . MET A  1 508 ? 173.093 236.304 169.392 1.00 111.69 ? 508 MET B CA  1 
ATOM   2326 C C   . MET A  1 508 ? 172.604 236.824 170.738 1.00 111.95 ? 508 MET B C   1 
ATOM   2327 O O   . MET A  1 508 ? 173.275 236.643 171.761 1.00 113.66 ? 508 MET B O   1 
ATOM   2328 C CB  . MET A  1 508 ? 173.803 237.409 168.611 1.00 110.20 ? 508 MET B CB  1 
ATOM   2329 C CG  . MET A  1 508 ? 174.423 236.943 167.304 1.00 112.91 ? 508 MET B CG  1 
ATOM   2330 S SD  . MET A  1 508 ? 174.342 238.190 166.004 1.00 118.66 ? 508 MET B SD  1 
ATOM   2331 C CE  . MET A  1 508 ? 173.007 237.544 165.000 1.00 110.58 ? 508 MET B CE  1 
ATOM   2332 N N   . VAL A  1 509 ? 171.437 237.471 170.758 1.00 111.16 ? 509 VAL B N   1 
ATOM   2333 C CA  . VAL A  1 509 ? 170.882 237.967 172.016 1.00 112.24 ? 509 VAL B CA  1 
ATOM   2334 C C   . VAL A  1 509 ? 170.575 236.809 172.956 1.00 109.99 ? 509 VAL B C   1 
ATOM   2335 O O   . VAL A  1 509 ? 170.865 236.870 174.159 1.00 108.70 ? 509 VAL B O   1 
ATOM   2336 C CB  . VAL A  1 509 ? 169.631 238.822 171.748 1.00 112.09 ? 509 VAL B CB  1 
ATOM   2337 C CG1 . VAL A  1 509 ? 169.350 239.735 172.931 1.00 110.47 ? 509 VAL B CG1 1 
ATOM   2338 C CG2 . VAL A  1 509 ? 169.805 239.630 170.471 1.00 110.05 ? 509 VAL B CG2 1 
ATOM   2339 N N   . PHE A  1 510 ? 169.974 235.741 172.428 1.00 102.69 ? 510 PHE B N   1 
ATOM   2340 C CA  . PHE A  1 510 ? 169.678 234.578 173.258 1.00 102.71 ? 510 PHE B CA  1 
ATOM   2341 C C   . PHE A  1 510 ? 170.955 233.917 173.761 1.00 100.17 ? 510 PHE B C   1 
ATOM   2342 O O   . PHE A  1 510 ? 171.017 233.467 174.910 1.00 102.09 ? 510 PHE B O   1 
ATOM   2343 C CB  . PHE A  1 510 ? 168.821 233.579 172.484 1.00 104.14 ? 510 PHE B CB  1 
ATOM   2344 C CG  . PHE A  1 510 ? 167.350 233.735 172.727 1.00 103.98 ? 510 PHE B CG  1 
ATOM   2345 C CD1 . PHE A  1 510 ? 166.855 233.805 174.017 1.00 101.10 ? 510 PHE B CD1 1 
ATOM   2346 C CD2 . PHE A  1 510 ? 166.463 233.816 171.668 1.00 106.09 ? 510 PHE B CD2 1 
ATOM   2347 C CE1 . PHE A  1 510 ? 165.504 233.950 174.248 1.00 102.24 ? 510 PHE B CE1 1 
ATOM   2348 C CE2 . PHE A  1 510 ? 165.109 233.962 171.892 1.00 103.23 ? 510 PHE B CE2 1 
ATOM   2349 C CZ  . PHE A  1 510 ? 164.629 234.029 173.184 1.00 102.02 ? 510 PHE B CZ  1 
ATOM   2350 N N   . PHE A  1 511 ? 171.984 233.845 172.914 1.00 96.88  ? 511 PHE B N   1 
ATOM   2351 C CA  . PHE A  1 511 ? 173.263 233.288 173.342 1.00 96.09  ? 511 PHE B CA  1 
ATOM   2352 C C   . PHE A  1 511 ? 173.866 234.116 174.466 1.00 97.99  ? 511 PHE B C   1 
ATOM   2353 O O   . PHE A  1 511 ? 174.392 233.572 175.443 1.00 102.72 ? 511 PHE B O   1 
ATOM   2354 C CB  . PHE A  1 511 ? 174.226 233.212 172.156 1.00 100.29 ? 511 PHE B CB  1 
ATOM   2355 C CG  . PHE A  1 511 ? 175.615 232.760 172.521 1.00 100.24 ? 511 PHE B CG  1 
ATOM   2356 C CD1 . PHE A  1 511 ? 176.578 233.672 172.928 1.00 99.42  ? 511 PHE B CD1 1 
ATOM   2357 C CD2 . PHE A  1 511 ? 175.960 231.422 172.454 1.00 99.25  ? 511 PHE B CD2 1 
ATOM   2358 C CE1 . PHE A  1 511 ? 177.849 233.255 173.263 1.00 99.77  ? 511 PHE B CE1 1 
ATOM   2359 C CE2 . PHE A  1 511 ? 177.232 231.002 172.784 1.00 100.51 ? 511 PHE B CE2 1 
ATOM   2360 C CZ  . PHE A  1 511 ? 178.175 231.918 173.191 1.00 100.62 ? 511 PHE B CZ  1 
ATOM   2361 N N   . TYR A  1 512 ? 173.816 235.442 174.332 1.00 101.46 ? 512 TYR B N   1 
ATOM   2362 C CA  . TYR A  1 512 ? 174.367 236.306 175.369 1.00 103.99 ? 512 TYR B CA  1 
ATOM   2363 C C   . TYR A  1 512 ? 173.590 236.170 176.671 1.00 102.50 ? 512 TYR B C   1 
ATOM   2364 O O   . TYR A  1 512 ? 174.186 236.147 177.750 1.00 99.92  ? 512 TYR B O   1 
ATOM   2365 C CB  . TYR A  1 512 ? 174.393 237.758 174.892 1.00 104.72 ? 512 TYR B CB  1 
ATOM   2366 C CG  . TYR A  1 512 ? 175.295 237.975 173.700 1.00 106.59 ? 512 TYR B CG  1 
ATOM   2367 C CD1 . TYR A  1 512 ? 176.432 237.197 173.521 1.00 103.43 ? 512 TYR B CD1 1 
ATOM   2368 C CD2 . TYR A  1 512 ? 175.022 238.962 172.763 1.00 106.12 ? 512 TYR B CD2 1 
ATOM   2369 C CE1 . TYR A  1 512 ? 177.266 237.389 172.437 1.00 104.60 ? 512 TYR B CE1 1 
ATOM   2370 C CE2 . TYR A  1 512 ? 175.850 239.161 171.674 1.00 106.21 ? 512 TYR B CE2 1 
ATOM   2371 C CZ  . TYR A  1 512 ? 176.971 238.372 171.517 1.00 107.34 ? 512 TYR B CZ  1 
ATOM   2372 O OH  . TYR A  1 512 ? 177.801 238.565 170.437 1.00 105.00 ? 512 TYR B OH  1 
ATOM   2373 N N   . LEU A  1 513 ? 172.262 236.069 176.593 1.00 93.84  ? 513 LEU B N   1 
ATOM   2374 C CA  . LEU A  1 513 ? 171.472 235.866 177.806 1.00 92.36  ? 513 LEU B CA  1 
ATOM   2375 C C   . LEU A  1 513 ? 171.785 234.523 178.457 1.00 91.41  ? 513 LEU B C   1 
ATOM   2376 O O   . LEU A  1 513 ? 171.910 234.433 179.687 1.00 90.99  ? 513 LEU B O   1 
ATOM   2377 C CB  . LEU A  1 513 ? 169.984 235.976 177.485 1.00 92.60  ? 513 LEU B CB  1 
ATOM   2378 C CG  . LEU A  1 513 ? 169.069 236.305 178.665 1.00 90.16  ? 513 LEU B CG  1 
ATOM   2379 C CD1 . LEU A  1 513 ? 169.674 237.392 179.541 1.00 89.23  ? 513 LEU B CD1 1 
ATOM   2380 C CD2 . LEU A  1 513 ? 167.692 236.715 178.169 1.00 91.97  ? 513 LEU B CD2 1 
ATOM   2381 N N   . TRP A  1 514 ? 171.910 233.468 177.647 1.00 89.72  ? 514 TRP B N   1 
ATOM   2382 C CA  . TRP A  1 514 ? 172.316 232.162 178.157 1.00 85.59  ? 514 TRP B CA  1 
ATOM   2383 C C   . TRP A  1 514 ? 173.658 232.235 178.871 1.00 81.96  ? 514 TRP B C   1 
ATOM   2384 O O   . TRP A  1 514 ? 173.806 231.730 179.987 1.00 87.45  ? 514 TRP B O   1 
ATOM   2385 C CB  . TRP A  1 514 ? 172.385 231.153 177.010 1.00 89.61  ? 514 TRP B CB  1 
ATOM   2386 C CG  . TRP A  1 514 ? 173.209 229.946 177.342 1.00 87.10  ? 514 TRP B CG  1 
ATOM   2387 C CD1 . TRP A  1 514 ? 173.209 229.243 178.511 1.00 88.33  ? 514 TRP B CD1 1 
ATOM   2388 C CD2 . TRP A  1 514 ? 174.208 229.343 176.514 1.00 88.25  ? 514 TRP B CD2 1 
ATOM   2389 N NE1 . TRP A  1 514 ? 174.128 228.229 178.452 1.00 85.43  ? 514 TRP B NE1 1 
ATOM   2390 C CE2 . TRP A  1 514 ? 174.752 228.265 177.234 1.00 84.46  ? 514 TRP B CE2 1 
ATOM   2391 C CE3 . TRP A  1 514 ? 174.683 229.600 175.227 1.00 92.44  ? 514 TRP B CE3 1 
ATOM   2392 C CZ2 . TRP A  1 514 ? 175.753 227.451 176.714 1.00 86.14  ? 514 TRP B CZ2 1 
ATOM   2393 C CZ3 . TRP A  1 514 ? 175.670 228.784 174.710 1.00 93.03  ? 514 TRP B CZ3 1 
ATOM   2394 C CH2 . TRP A  1 514 ? 176.192 227.721 175.451 1.00 89.09  ? 514 TRP B CH2 1 
ATOM   2395 N N   . ILE A  1 515 ? 174.657 232.836 178.224 1.00 79.01  ? 515 ILE B N   1 
ATOM   2396 C CA  . ILE A  1 515 ? 175.985 232.911 178.820 1.00 81.27  ? 515 ILE B CA  1 
ATOM   2397 C C   . ILE A  1 515 ? 175.954 233.774 180.073 1.00 84.76  ? 515 ILE B C   1 
ATOM   2398 O O   . ILE A  1 515 ? 176.664 233.499 181.047 1.00 83.70  ? 515 ILE B O   1 
ATOM   2399 C CB  . ILE A  1 515 ? 177.000 233.427 177.783 1.00 85.18  ? 515 ILE B CB  1 
ATOM   2400 C CG1 . ILE A  1 515 ? 177.482 232.269 176.909 1.00 83.21  ? 515 ILE B CG1 1 
ATOM   2401 C CG2 . ILE A  1 515 ? 178.187 234.104 178.459 1.00 85.02  ? 515 ILE B CG2 1 
ATOM   2402 C CD1 . ILE A  1 515 ? 178.463 231.359 177.593 1.00 81.22  ? 515 ILE B CD1 1 
ATOM   2403 N N   . VAL A  1 516 ? 175.122 234.817 180.080 1.00 83.48  ? 516 VAL B N   1 
ATOM   2404 C CA  . VAL A  1 516 ? 174.995 235.669 181.254 1.00 82.56  ? 516 VAL B CA  1 
ATOM   2405 C C   . VAL A  1 516 ? 174.431 234.885 182.430 1.00 81.17  ? 516 VAL B C   1 
ATOM   2406 O O   . VAL A  1 516 ? 174.909 235.020 183.557 1.00 77.45  ? 516 VAL B O   1 
ATOM   2407 C CB  . VAL A  1 516 ? 174.136 236.902 180.921 1.00 85.25  ? 516 VAL B CB  1 
ATOM   2408 C CG1 . VAL A  1 516 ? 173.493 237.473 182.177 1.00 82.15  ? 516 VAL B CG1 1 
ATOM   2409 C CG2 . VAL A  1 516 ? 174.986 237.958 180.237 1.00 85.12  ? 516 VAL B CG2 1 
ATOM   2410 N N   . PHE A  1 517 ? 173.413 234.052 182.192 1.00 83.44  ? 517 PHE B N   1 
ATOM   2411 C CA  . PHE A  1 517 ? 172.845 233.258 183.284 1.00 81.16  ? 517 PHE B CA  1 
ATOM   2412 C C   . PHE A  1 517 ? 173.783 232.128 183.700 1.00 78.04  ? 517 PHE B C   1 
ATOM   2413 O O   . PHE A  1 517 ? 173.845 231.761 184.883 1.00 78.18  ? 517 PHE B O   1 
ATOM   2414 C CB  . PHE A  1 517 ? 171.470 232.735 182.886 1.00 73.44  ? 517 PHE B CB  1 
ATOM   2415 C CG  . PHE A  1 517 ? 170.365 233.699 183.189 1.00 72.92  ? 517 PHE B CG  1 
ATOM   2416 C CD1 . PHE A  1 517 ? 169.845 234.513 182.200 1.00 78.24  ? 517 PHE B CD1 1 
ATOM   2417 C CD2 . PHE A  1 517 ? 169.861 233.806 184.472 1.00 73.10  ? 517 PHE B CD2 1 
ATOM   2418 C CE1 . PHE A  1 517 ? 168.836 235.412 182.486 1.00 83.04  ? 517 PHE B CE1 1 
ATOM   2419 C CE2 . PHE A  1 517 ? 168.852 234.698 184.762 1.00 79.38  ? 517 PHE B CE2 1 
ATOM   2420 C CZ  . PHE A  1 517 ? 168.336 235.501 183.767 1.00 81.82  ? 517 PHE B CZ  1 
ATOM   2421 N N   . TYR A  1 518 ? 174.518 231.569 182.744 1.00 76.69  ? 518 TYR B N   1 
ATOM   2422 C CA  . TYR A  1 518 ? 175.758 230.881 183.045 1.00 72.31  ? 518 TYR B CA  1 
ATOM   2423 C C   . TYR A  1 518 ? 176.685 231.855 183.769 1.00 73.91  ? 518 TYR B C   1 
ATOM   2424 O O   . TYR A  1 518 ? 176.437 233.056 183.818 1.00 68.17  ? 518 TYR B O   1 
ATOM   2425 C CB  . TYR A  1 518 ? 176.387 230.363 181.749 1.00 72.72  ? 518 TYR B CB  1 
ATOM   2426 C CG  . TYR A  1 518 ? 177.528 229.380 181.893 1.00 70.08  ? 518 TYR B CG  1 
ATOM   2427 C CD1 . TYR A  1 518 ? 177.715 228.649 183.056 1.00 71.46  ? 518 TYR B CD1 1 
ATOM   2428 C CD2 . TYR A  1 518 ? 178.420 229.181 180.847 1.00 75.74  ? 518 TYR B CD2 1 
ATOM   2429 C CE1 . TYR A  1 518 ? 178.762 227.758 183.174 1.00 76.80  ? 518 TYR B CE1 1 
ATOM   2430 C CE2 . TYR A  1 518 ? 179.466 228.290 180.956 1.00 72.73  ? 518 TYR B CE2 1 
ATOM   2431 C CZ  . TYR A  1 518 ? 179.633 227.581 182.123 1.00 71.69  ? 518 TYR B CZ  1 
ATOM   2432 O OH  . TYR A  1 518 ? 180.672 226.689 182.244 1.00 71.33  ? 518 TYR B OH  1 
ATOM   2433 N N   . ILE A  1 519 ? 177.759 231.326 184.344 1.00 73.54  ? 519 ILE B N   1 
ATOM   2434 C CA  . ILE A  1 519 ? 178.654 232.093 185.208 1.00 71.15  ? 519 ILE B CA  1 
ATOM   2435 C C   . ILE A  1 519 ? 177.945 232.404 186.522 1.00 73.97  ? 519 ILE B C   1 
ATOM   2436 O O   . ILE A  1 519 ? 178.467 232.066 187.585 1.00 70.71  ? 519 ILE B O   1 
ATOM   2437 C CB  . ILE A  1 519 ? 179.184 233.371 184.527 1.00 69.73  ? 519 ILE B CB  1 
ATOM   2438 C CG1 . ILE A  1 519 ? 179.753 233.040 183.145 1.00 68.93  ? 519 ILE B CG1 1 
ATOM   2439 C CG2 . ILE A  1 519 ? 180.228 234.049 185.399 1.00 71.14  ? 519 ILE B CG2 1 
ATOM   2440 C CD1 . ILE A  1 519 ? 180.078 234.255 182.311 1.00 69.62  ? 519 ILE B CD1 1 
ATOM   2441 N N   . ILE A  1 520 ? 176.750 233.015 186.490 1.00 74.41  ? 520 ILE B N   1 
ATOM   2442 C CA  . ILE A  1 520 ? 176.011 233.135 187.749 1.00 71.32  ? 520 ILE B CA  1 
ATOM   2443 C C   . ILE A  1 520 ? 175.622 231.763 188.279 1.00 68.49  ? 520 ILE B C   1 
ATOM   2444 O O   . ILE A  1 520 ? 175.770 231.489 189.472 1.00 68.02  ? 520 ILE B O   1 
ATOM   2445 C CB  . ILE A  1 520 ? 174.773 234.053 187.659 1.00 70.24  ? 520 ILE B CB  1 
ATOM   2446 C CG1 . ILE A  1 520 ? 175.008 235.342 186.878 1.00 70.74  ? 520 ILE B CG1 1 
ATOM   2447 C CG2 . ILE A  1 520 ? 174.234 234.361 189.042 1.00 69.33  ? 520 ILE B CG2 1 
ATOM   2448 C CD1 . ILE A  1 520 ? 173.792 235.754 186.091 1.00 68.02  ? 520 ILE B CD1 1 
ATOM   2449 N N   . SER A  1 521 ? 175.114 230.882 187.416 1.00 64.77  ? 521 SER B N   1 
ATOM   2450 C CA  . SER A  1 521 ? 174.751 229.548 187.890 1.00 62.70  ? 521 SER B CA  1 
ATOM   2451 C C   . SER A  1 521 ? 175.967 228.813 188.451 1.00 62.69  ? 521 SER B C   1 
ATOM   2452 O O   . SER A  1 521 ? 175.922 228.255 189.559 1.00 65.41  ? 521 SER B O   1 
ATOM   2453 C CB  . SER A  1 521 ? 174.108 228.750 186.758 1.00 57.74  ? 521 SER B CB  1 
ATOM   2454 O OG  . SER A  1 521 ? 174.022 227.380 187.095 1.00 52.09  ? 521 SER B OG  1 
ATOM   2455 N N   . SER A  1 522 ? 177.078 228.833 187.709 1.00 55.75  ? 522 SER B N   1 
ATOM   2456 C CA  . SER A  1 522 ? 178.282 228.133 188.145 1.00 48.83  ? 522 SER B CA  1 
ATOM   2457 C C   . SER A  1 522 ? 178.847 228.725 189.428 1.00 58.22  ? 522 SER B C   1 
ATOM   2458 O O   . SER A  1 522 ? 179.240 227.982 190.330 1.00 62.30  ? 522 SER B O   1 
ATOM   2459 C CB  . SER A  1 522 ? 179.333 228.156 187.039 1.00 49.24  ? 522 SER B CB  1 
ATOM   2460 O OG  . SER A  1 522 ? 179.080 227.138 186.091 1.00 61.71  ? 522 SER B OG  1 
ATOM   2461 N N   . CYS A  1 523 ? 178.894 230.055 189.539 1.00 61.08  ? 523 CYS B N   1 
ATOM   2462 C CA  . CYS A  1 523 ? 179.454 230.677 190.731 1.00 62.66  ? 523 CYS B CA  1 
ATOM   2463 C C   . CYS A  1 523 ? 178.539 230.487 191.932 1.00 56.24  ? 523 CYS B C   1 
ATOM   2464 O O   . CYS A  1 523 ? 179.017 230.289 193.051 1.00 49.23  ? 523 CYS B O   1 
ATOM   2465 C CB  . CYS A  1 523 ? 179.711 232.161 190.473 1.00 60.98  ? 523 CYS B CB  1 
ATOM   2466 S SG  . CYS A  1 523 ? 181.382 232.538 189.901 1.00 67.92  ? 523 CYS B SG  1 
ATOM   2467 N N   . TYR A  1 524 ? 177.224 230.540 191.720 1.00 55.16  ? 524 TYR B N   1 
ATOM   2468 C CA  . TYR A  1 524 ? 176.275 230.245 192.784 1.00 55.69  ? 524 TYR B CA  1 
ATOM   2469 C C   . TYR A  1 524 ? 176.518 228.852 193.345 1.00 59.37  ? 524 TYR B C   1 
ATOM   2470 O O   . TYR A  1 524 ? 176.729 228.678 194.554 1.00 66.23  ? 524 TYR B O   1 
ATOM   2471 C CB  . TYR A  1 524 ? 174.857 230.369 192.224 1.00 51.77  ? 524 TYR B CB  1 
ATOM   2472 C CG  . TYR A  1 524 ? 173.764 230.675 193.219 1.00 51.11  ? 524 TYR B CG  1 
ATOM   2473 C CD1 . TYR A  1 524 ? 173.915 230.401 194.568 1.00 55.13  ? 524 TYR B CD1 1 
ATOM   2474 C CD2 . TYR A  1 524 ? 172.571 231.239 192.795 1.00 48.66  ? 524 TYR B CD2 1 
ATOM   2475 C CE1 . TYR A  1 524 ? 172.905 230.685 195.466 1.00 60.04  ? 524 TYR B CE1 1 
ATOM   2476 C CE2 . TYR A  1 524 ? 171.562 231.524 193.680 1.00 48.89  ? 524 TYR B CE2 1 
ATOM   2477 C CZ  . TYR A  1 524 ? 171.731 231.246 195.013 1.00 59.32  ? 524 TYR B CZ  1 
ATOM   2478 O OH  . TYR A  1 524 ? 170.716 231.532 195.891 1.00 61.74  ? 524 TYR B OH  1 
ATOM   2479 N N   . THR A  1 525 ? 176.547 227.849 192.462 1.00 55.91  ? 525 THR B N   1 
ATOM   2480 C CA  . THR A  1 525 ? 176.762 226.479 192.913 1.00 42.86  ? 525 THR B CA  1 
ATOM   2481 C C   . THR A  1 525 ? 178.144 226.306 193.532 1.00 53.05  ? 525 THR B C   1 
ATOM   2482 O O   . THR A  1 525 ? 178.299 225.592 194.527 1.00 61.22  ? 525 THR B O   1 
ATOM   2483 C CB  . THR A  1 525 ? 176.564 225.513 191.748 1.00 48.32  ? 525 THR B CB  1 
ATOM   2484 O OG1 . THR A  1 525 ? 177.106 226.088 190.554 1.00 62.64  ? 525 THR B OG1 1 
ATOM   2485 C CG2 . THR A  1 525 ? 175.086 225.243 191.535 1.00 50.70  ? 525 THR B CG2 1 
ATOM   2486 N N   . LEU A  1 526 ? 179.158 226.971 192.973 1.00 48.70  ? 526 LEU B N   1 
ATOM   2487 C CA  . LEU A  1 526 ? 180.526 226.807 193.451 1.00 46.41  ? 526 LEU B CA  1 
ATOM   2488 C C   . LEU A  1 526 ? 180.708 227.411 194.838 1.00 55.21  ? 526 LEU B C   1 
ATOM   2489 O O   . LEU A  1 526 ? 181.305 226.786 195.724 1.00 60.25  ? 526 LEU B O   1 
ATOM   2490 C CB  . LEU A  1 526 ? 181.493 227.440 192.453 1.00 40.86  ? 526 LEU B CB  1 
ATOM   2491 C CG  . LEU A  1 526 ? 182.969 227.501 192.837 1.00 45.60  ? 526 LEU B CG  1 
ATOM   2492 C CD1 . LEU A  1 526 ? 183.517 226.104 193.023 1.00 52.74  ? 526 LEU B CD1 1 
ATOM   2493 C CD2 . LEU A  1 526 ? 183.758 228.252 191.780 1.00 47.42  ? 526 LEU B CD2 1 
ATOM   2494 N N   . ILE A  1 527 ? 180.215 228.633 195.043 1.00 49.12  ? 527 ILE B N   1 
ATOM   2495 C CA  . ILE A  1 527 ? 180.309 229.260 196.356 1.00 49.13  ? 527 ILE B CA  1 
ATOM   2496 C C   . ILE A  1 527 ? 179.493 228.477 197.371 1.00 51.31  ? 527 ILE B C   1 
ATOM   2497 O O   . ILE A  1 527 ? 179.909 228.313 198.524 1.00 50.01  ? 527 ILE B O   1 
ATOM   2498 C CB  . ILE A  1 527 ? 179.871 230.733 196.288 1.00 49.59  ? 527 ILE B CB  1 
ATOM   2499 C CG1 . ILE A  1 527 ? 180.733 231.498 195.283 1.00 56.71  ? 527 ILE B CG1 1 
ATOM   2500 C CG2 . ILE A  1 527 ? 179.959 231.377 197.660 1.00 49.12  ? 527 ILE B CG2 1 
ATOM   2501 C CD1 . ILE A  1 527 ? 180.177 232.850 194.907 1.00 55.90  ? 527 ILE B CD1 1 
ATOM   2502 N N   . TRP A  1 528 ? 178.328 227.965 196.962 1.00 53.68  ? 528 TRP B N   1 
ATOM   2503 C CA  . TRP A  1 528 ? 177.562 227.110 197.859 1.00 44.38  ? 528 TRP B CA  1 
ATOM   2504 C C   . TRP A  1 528 ? 178.376 225.891 198.272 1.00 50.42  ? 528 TRP B C   1 
ATOM   2505 O O   . TRP A  1 528 ? 178.497 225.588 199.463 1.00 59.35  ? 528 TRP B O   1 
ATOM   2506 C CB  . TRP A  1 528 ? 176.257 226.689 197.192 1.00 43.60  ? 528 TRP B CB  1 
ATOM   2507 C CG  . TRP A  1 528 ? 175.205 226.287 198.164 1.00 47.27  ? 528 TRP B CG  1 
ATOM   2508 C CD1 . TRP A  1 528 ? 174.805 225.020 198.461 1.00 51.07  ? 528 TRP B CD1 1 
ATOM   2509 C CD2 . TRP A  1 528 ? 174.421 227.158 198.981 1.00 48.93  ? 528 TRP B CD2 1 
ATOM   2510 N NE1 . TRP A  1 528 ? 173.814 225.047 199.410 1.00 52.94  ? 528 TRP B NE1 1 
ATOM   2511 C CE2 . TRP A  1 528 ? 173.562 226.350 199.748 1.00 51.58  ? 528 TRP B CE2 1 
ATOM   2512 C CE3 . TRP A  1 528 ? 174.360 228.544 199.138 1.00 54.91  ? 528 TRP B CE3 1 
ATOM   2513 C CZ2 . TRP A  1 528 ? 172.652 226.880 200.654 1.00 56.04  ? 528 TRP B CZ2 1 
ATOM   2514 C CZ3 . TRP A  1 528 ? 173.460 229.067 200.039 1.00 60.61  ? 528 TRP B CZ3 1 
ATOM   2515 C CH2 . TRP A  1 528 ? 172.616 228.239 200.786 1.00 61.70  ? 528 TRP B CH2 1 
ATOM   2516 N N   . ASP A  1 529 ? 178.984 225.210 197.298 1.00 47.96  ? 529 ASP B N   1 
ATOM   2517 C CA  . ASP A  1 529 ? 179.767 224.016 197.594 1.00 46.91  ? 529 ASP B CA  1 
ATOM   2518 C C   . ASP A  1 529 ? 180.921 224.326 198.537 1.00 53.21  ? 529 ASP B C   1 
ATOM   2519 O O   . ASP A  1 529 ? 181.165 223.585 199.496 1.00 55.95  ? 529 ASP B O   1 
ATOM   2520 C CB  . ASP A  1 529 ? 180.298 223.406 196.297 1.00 42.70  ? 529 ASP B CB  1 
ATOM   2521 C CG  . ASP A  1 529 ? 179.205 222.803 195.444 1.00 50.29  ? 529 ASP B CG  1 
ATOM   2522 O OD1 . ASP A  1 529 ? 178.046 222.757 195.904 1.00 56.48  ? 529 ASP B OD1 1 
ATOM   2523 O OD2 . ASP A  1 529 ? 179.505 222.380 194.310 1.00 42.69  ? 529 ASP B OD2 1 
ATOM   2524 N N   . LEU A  1 530 ? 181.640 225.418 198.287 1.00 48.49  ? 530 LEU B N   1 
ATOM   2525 C CA  . LEU A  1 530 ? 182.831 225.714 199.073 1.00 46.34  ? 530 LEU B CA  1 
ATOM   2526 C C   . LEU A  1 530 ? 182.534 226.377 200.411 1.00 53.89  ? 530 LEU B C   1 
ATOM   2527 O O   . LEU A  1 530 ? 183.424 226.414 201.267 1.00 53.50  ? 530 LEU B O   1 
ATOM   2528 C CB  . LEU A  1 530 ? 183.789 226.599 198.275 1.00 35.35  ? 530 LEU B CB  1 
ATOM   2529 C CG  . LEU A  1 530 ? 184.170 226.099 196.884 1.00 43.66  ? 530 LEU B CG  1 
ATOM   2530 C CD1 . LEU A  1 530 ? 185.011 227.136 196.162 1.00 51.70  ? 530 LEU B CD1 1 
ATOM   2531 C CD2 . LEU A  1 530 ? 184.902 224.776 196.983 1.00 52.84  ? 530 LEU B CD2 1 
ATOM   2532 N N   . LYS A  1 531 ? 181.327 226.898 200.627 1.00 62.86  ? 531 LYS B N   1 
ATOM   2533 C CA  . LYS A  1 531 ? 181.018 227.581 201.875 1.00 57.18  ? 531 LYS B CA  1 
ATOM   2534 C C   . LYS A  1 531 ? 180.066 226.807 202.772 1.00 62.23  ? 531 LYS B C   1 
ATOM   2535 O O   . LYS A  1 531 ? 180.320 226.684 203.973 1.00 63.36  ? 531 LYS B O   1 
ATOM   2536 C CB  . LYS A  1 531 ? 180.437 228.972 201.585 1.00 52.50  ? 531 LYS B CB  1 
ATOM   2537 C CG  . LYS A  1 531 ? 181.444 230.094 201.749 1.00 59.50  ? 531 LYS B CG  1 
ATOM   2538 C CD  . LYS A  1 531 ? 181.695 230.392 203.218 1.00 58.74  ? 531 LYS B CD  1 
ATOM   2539 C CE  . LYS A  1 531 ? 182.657 231.557 203.393 1.00 63.23  ? 531 LYS B CE  1 
ATOM   2540 N NZ  . LYS A  1 531 ? 182.141 232.814 202.786 1.00 65.12  ? 531 LYS B NZ  1 
ATOM   2541 N N   . MET A  1 532 ? 178.965 226.286 202.234 1.00 58.53  ? 532 MET B N   1 
ATOM   2542 C CA  . MET A  1 532 ? 177.945 225.661 203.062 1.00 54.00  ? 532 MET B CA  1 
ATOM   2543 C C   . MET A  1 532 ? 177.934 224.145 202.955 1.00 57.45  ? 532 MET B C   1 
ATOM   2544 O O   . MET A  1 532 ? 177.758 223.461 203.968 1.00 59.30  ? 532 MET B O   1 
ATOM   2545 C CB  . MET A  1 532 ? 176.569 226.211 202.690 1.00 49.85  ? 532 MET B CB  1 
ATOM   2546 C CG  . MET A  1 532 ? 176.475 227.710 202.851 1.00 59.51  ? 532 MET B CG  1 
ATOM   2547 S SD  . MET A  1 532 ? 175.802 228.159 204.452 1.00 76.47  ? 532 MET B SD  1 
ATOM   2548 C CE  . MET A  1 532 ? 174.076 228.269 204.028 1.00 55.78  ? 532 MET B CE  1 
ATOM   2549 N N   . ASP A  1 533 ? 178.106 223.600 201.750 1.00 48.62  ? 533 ASP B N   1 
ATOM   2550 C CA  . ASP A  1 533 ? 178.185 222.151 201.602 1.00 43.88  ? 533 ASP B CA  1 
ATOM   2551 C C   . ASP A  1 533 ? 179.400 221.595 202.331 1.00 53.75  ? 533 ASP B C   1 
ATOM   2552 O O   . ASP A  1 533 ? 179.287 220.662 203.133 1.00 60.29  ? 533 ASP B O   1 
ATOM   2553 C CB  . ASP A  1 533 ? 178.229 221.775 200.122 1.00 36.99  ? 533 ASP B CB  1 
ATOM   2554 C CG  . ASP A  1 533 ? 176.854 221.707 199.497 1.00 47.11  ? 533 ASP B CG  1 
ATOM   2555 O OD1 . ASP A  1 533 ? 175.858 221.807 200.241 1.00 55.06  ? 533 ASP B OD1 1 
ATOM   2556 O OD2 . ASP A  1 533 ? 176.768 221.551 198.262 1.00 50.99  ? 533 ASP B OD2 1 
ATOM   2557 N N   . TRP A  1 534 ? 180.574 222.164 202.069 1.00 45.70  ? 534 TRP B N   1 
ATOM   2558 C CA  . TRP A  1 534 ? 181.807 221.675 202.672 1.00 38.38  ? 534 TRP B CA  1 
ATOM   2559 C C   . TRP A  1 534 ? 182.153 222.384 203.971 1.00 47.58  ? 534 TRP B C   1 
ATOM   2560 O O   . TRP A  1 534 ? 182.859 221.811 204.808 1.00 50.08  ? 534 TRP B O   1 
ATOM   2561 C CB  . TRP A  1 534 ? 182.970 221.830 201.690 1.00 42.61  ? 534 TRP B CB  1 
ATOM   2562 C CG  . TRP A  1 534 ? 182.829 221.010 200.452 1.00 43.34  ? 534 TRP B CG  1 
ATOM   2563 C CD1 . TRP A  1 534 ? 181.802 220.178 200.133 1.00 49.31  ? 534 TRP B CD1 1 
ATOM   2564 C CD2 . TRP A  1 534 ? 183.748 220.949 199.358 1.00 45.12  ? 534 TRP B CD2 1 
ATOM   2565 N NE1 . TRP A  1 534 ? 182.024 219.598 198.910 1.00 45.78  ? 534 TRP B NE1 1 
ATOM   2566 C CE2 . TRP A  1 534 ? 183.213 220.058 198.413 1.00 38.18  ? 534 TRP B CE2 1 
ATOM   2567 C CE3 . TRP A  1 534 ? 184.973 221.563 199.088 1.00 47.83  ? 534 TRP B CE3 1 
ATOM   2568 C CZ2 . TRP A  1 534 ? 183.859 219.762 197.221 1.00 42.00  ? 534 TRP B CZ2 1 
ATOM   2569 C CZ3 . TRP A  1 534 ? 185.611 221.269 197.903 1.00 47.07  ? 534 TRP B CZ3 1 
ATOM   2570 C CH2 . TRP A  1 534 ? 185.054 220.377 196.984 1.00 51.09  ? 534 TRP B CH2 1 
ATOM   2571 N N   . GLY A  1 535 ? 181.676 223.610 204.161 1.00 60.24  ? 535 GLY B N   1 
ATOM   2572 C CA  . GLY A  1 535 ? 182.030 224.378 205.335 1.00 61.29  ? 535 GLY B CA  1 
ATOM   2573 C C   . GLY A  1 535 ? 183.392 225.027 205.282 1.00 62.00  ? 535 GLY B C   1 
ATOM   2574 O O   . GLY A  1 535 ? 183.873 225.507 206.314 1.00 65.10  ? 535 GLY B O   1 
ATOM   2575 N N   . LEU A  1 536 ? 184.027 225.060 204.115 1.00 64.14  ? 536 LEU B N   1 
ATOM   2576 C CA  . LEU A  1 536 ? 185.362 225.619 203.987 1.00 69.33  ? 536 LEU B CA  1 
ATOM   2577 C C   . LEU A  1 536 ? 185.291 227.145 203.961 1.00 70.42  ? 536 LEU B C   1 
ATOM   2578 O O   . LEU A  1 536 ? 184.217 227.745 204.053 1.00 69.61  ? 536 LEU B O   1 
ATOM   2579 C CB  . LEU A  1 536 ? 186.047 225.068 202.739 1.00 68.37  ? 536 LEU B CB  1 
ATOM   2580 C CG  . LEU A  1 536 ? 186.133 223.543 202.640 1.00 58.07  ? 536 LEU B CG  1 
ATOM   2581 C CD1 . LEU A  1 536 ? 187.040 223.125 201.498 1.00 55.15  ? 536 LEU B CD1 1 
ATOM   2582 C CD2 . LEU A  1 536 ? 186.607 222.940 203.949 1.00 56.97  ? 536 LEU B CD2 1 
ATOM   2583 N N   . PHE A  1 537 ? 186.459 227.781 203.838 1.00 67.64  ? 537 PHE B N   1 
ATOM   2584 C CA  . PHE A  1 537 ? 186.588 229.241 203.892 1.00 63.63  ? 537 PHE B CA  1 
ATOM   2585 C C   . PHE A  1 537 ? 185.998 229.810 205.176 1.00 65.75  ? 537 PHE B C   1 
ATOM   2586 O O   . PHE A  1 537 ? 185.445 230.911 205.182 1.00 71.18  ? 537 PHE B O   1 
ATOM   2587 C CB  . PHE A  1 537 ? 185.954 229.940 202.680 1.00 65.78  ? 537 PHE B CB  1 
ATOM   2588 C CG  . PHE A  1 537 ? 186.526 229.534 201.340 1.00 70.06  ? 537 PHE B CG  1 
ATOM   2589 C CD1 . PHE A  1 537 ? 186.216 230.271 200.211 1.00 70.02  ? 537 PHE B CD1 1 
ATOM   2590 C CD2 . PHE A  1 537 ? 187.392 228.462 201.207 1.00 68.91  ? 537 PHE B CD2 1 
ATOM   2591 C CE1 . PHE A  1 537 ? 186.731 229.928 198.977 1.00 71.96  ? 537 PHE B CE1 1 
ATOM   2592 C CE2 . PHE A  1 537 ? 187.908 228.117 199.977 1.00 68.18  ? 537 PHE B CE2 1 
ATOM   2593 C CZ  . PHE A  1 537 ? 187.579 228.850 198.861 1.00 71.08  ? 537 PHE B CZ  1 
ATOM   2594 N N   . ASP A  1 538 ? 186.107 229.064 206.269 1.00 77.48  ? 538 ASP B N   1 
ATOM   2595 C CA  . ASP A  1 538 ? 185.539 229.500 207.534 1.00 83.78  ? 538 ASP B CA  1 
ATOM   2596 C C   . ASP A  1 538 ? 186.425 230.560 208.172 1.00 86.25  ? 538 ASP B C   1 
ATOM   2597 O O   . ASP A  1 538 ? 187.655 230.498 208.087 1.00 86.05  ? 538 ASP B O   1 
ATOM   2598 C CB  . ASP A  1 538 ? 185.365 228.311 208.477 1.00 83.74  ? 538 ASP B CB  1 
ATOM   2599 C CG  . ASP A  1 538 ? 184.798 228.713 209.823 1.00 88.76  ? 538 ASP B CG  1 
ATOM   2600 O OD1 . ASP A  1 538 ? 183.587 228.509 210.040 1.00 88.59  ? 538 ASP B OD1 1 
ATOM   2601 O OD2 . ASP A  1 538 ? 185.561 229.225 210.667 1.00 92.69  ? 538 ASP B OD2 1 
ATOM   2602 N N   . LYS A  1 539 ? 185.786 231.541 208.813 1.00 91.06  ? 539 LYS B N   1 
ATOM   2603 C CA  . LYS A  1 539 ? 186.524 232.642 209.422 1.00 94.53  ? 539 LYS B CA  1 
ATOM   2604 C C   . LYS A  1 539 ? 187.407 232.161 210.568 1.00 94.85  ? 539 LYS B C   1 
ATOM   2605 O O   . LYS A  1 539 ? 188.546 232.620 210.715 1.00 94.22  ? 539 LYS B O   1 
ATOM   2606 C CB  . LYS A  1 539 ? 185.549 233.714 209.908 1.00 95.53  ? 539 LYS B CB  1 
ATOM   2607 C CG  . LYS A  1 539 ? 184.490 234.102 208.883 1.00 94.35  ? 539 LYS B CG  1 
ATOM   2608 C CD  . LYS A  1 539 ? 183.409 234.975 209.505 1.00 92.16  ? 539 LYS B CD  1 
ATOM   2609 C CE  . LYS A  1 539 ? 182.320 235.313 208.499 1.00 91.59  ? 539 LYS B CE  1 
ATOM   2610 N NZ  . LYS A  1 539 ? 181.218 236.101 209.118 1.00 90.50  ? 539 LYS B NZ  1 
ATOM   2611 N N   . ASN A  1 540 ? 186.904 231.239 211.388 1.00 99.42  ? 540 ASN B N   1 
ATOM   2612 C CA  . ASN A  1 540 ? 187.613 230.774 212.574 1.00 98.36  ? 540 ASN B CA  1 
ATOM   2613 C C   . ASN A  1 540 ? 188.587 229.638 212.283 1.00 99.22  ? 540 ASN B C   1 
ATOM   2614 O O   . ASN A  1 540 ? 188.936 228.892 213.207 1.00 99.53  ? 540 ASN B O   1 
ATOM   2615 C CB  . ASN A  1 540 ? 186.610 230.339 213.645 1.00 94.40  ? 540 ASN B CB  1 
ATOM   2616 C CG  . ASN A  1 540 ? 185.346 231.175 213.632 1.00 97.69  ? 540 ASN B CG  1 
ATOM   2617 O OD1 . ASN A  1 540 ? 184.604 231.186 212.650 1.00 97.41  ? 540 ASN B OD1 1 
ATOM   2618 N ND2 . ASN A  1 540 ? 185.097 231.887 214.725 1.00 99.12  ? 540 ASN B ND2 1 
ATOM   2619 N N   . ALA A  1 541 ? 189.027 229.485 211.032 1.00 93.71  ? 541 ALA B N   1 
ATOM   2620 C CA  . ALA A  1 541 ? 189.959 228.411 210.700 1.00 90.61  ? 541 ALA B CA  1 
ATOM   2621 C C   . ALA A  1 541 ? 191.281 228.574 211.439 1.00 93.70  ? 541 ALA B C   1 
ATOM   2622 O O   . ALA A  1 541 ? 191.835 227.598 211.957 1.00 88.41  ? 541 ALA B O   1 
ATOM   2623 C CB  . ALA A  1 541 ? 190.192 228.367 209.191 1.00 89.44  ? 541 ALA B CB  1 
ATOM   2624 N N   . GLY A  1 542 ? 191.801 229.797 211.500 1.00 107.22 ? 542 GLY B N   1 
ATOM   2625 C CA  . GLY A  1 542 ? 193.051 230.046 212.190 1.00 107.18 ? 542 GLY B CA  1 
ATOM   2626 C C   . GLY A  1 542 ? 194.262 229.504 211.459 1.00 106.57 ? 542 GLY B C   1 
ATOM   2627 O O   . GLY A  1 542 ? 194.670 230.049 210.429 1.00 105.77 ? 542 GLY B O   1 
ATOM   2628 N N   . GLU A  1 543 ? 194.849 228.429 211.993 1.00 105.68 ? 543 GLU B N   1 
ATOM   2629 C CA  . GLU A  1 543 ? 196.050 227.860 211.388 1.00 107.24 ? 543 GLU B CA  1 
ATOM   2630 C C   . GLU A  1 543 ? 195.775 227.348 209.979 1.00 108.02 ? 543 GLU B C   1 
ATOM   2631 O O   . GLU A  1 543 ? 196.621 227.481 209.087 1.00 106.01 ? 543 GLU B O   1 
ATOM   2632 C CB  . GLU A  1 543 ? 196.615 226.748 212.280 1.00 105.78 ? 543 GLU B CB  1 
ATOM   2633 C CG  . GLU A  1 543 ? 195.826 225.439 212.305 1.00 105.32 ? 543 GLU B CG  1 
ATOM   2634 C CD  . GLU A  1 543 ? 194.420 225.591 212.862 1.00 106.19 ? 543 GLU B CD  1 
ATOM   2635 O OE1 . GLU A  1 543 ? 194.158 226.586 213.571 1.00 104.20 ? 543 GLU B OE1 1 
ATOM   2636 O OE2 . GLU A  1 543 ? 193.575 224.714 212.588 1.00 105.76 ? 543 GLU B OE2 1 
ATOM   2637 N N   . ASN A  1 544 ? 194.603 226.759 209.757 1.00 96.64  ? 544 ASN B N   1 
ATOM   2638 C CA  . ASN A  1 544 ? 194.222 226.351 208.413 1.00 92.78  ? 544 ASN B CA  1 
ATOM   2639 C C   . ASN A  1 544 ? 193.905 227.577 207.567 1.00 93.44  ? 544 ASN B C   1 
ATOM   2640 O O   . ASN A  1 544 ? 193.227 228.504 208.017 1.00 95.61  ? 544 ASN B O   1 
ATOM   2641 C CB  . ASN A  1 544 ? 193.016 225.415 208.463 1.00 93.38  ? 544 ASN B CB  1 
ATOM   2642 C CG  . ASN A  1 544 ? 193.285 224.164 209.274 1.00 94.55  ? 544 ASN B CG  1 
ATOM   2643 O OD1 . ASN A  1 544 ? 194.421 223.702 209.362 1.00 91.65  ? 544 ASN B OD1 1 
ATOM   2644 N ND2 . ASN A  1 544 ? 192.238 223.609 209.872 1.00 95.76  ? 544 ASN B ND2 1 
ATOM   2645 N N   . THR A  1 545 ? 194.401 227.581 206.335 1.00 87.62  ? 545 THR B N   1 
ATOM   2646 C CA  . THR A  1 545 ? 194.225 228.706 205.427 1.00 92.49  ? 545 THR B CA  1 
ATOM   2647 C C   . THR A  1 545 ? 193.110 228.380 204.441 1.00 87.44  ? 545 THR B C   1 
ATOM   2648 O O   . THR A  1 545 ? 193.170 227.358 203.749 1.00 82.27  ? 545 THR B O   1 
ATOM   2649 C CB  . THR A  1 545 ? 195.525 229.021 204.686 1.00 93.42  ? 545 THR B CB  1 
ATOM   2650 O OG1 . THR A  1 545 ? 195.634 228.181 203.531 1.00 91.75  ? 545 THR B OG1 1 
ATOM   2651 C CG2 . THR A  1 545 ? 196.727 228.782 205.591 1.00 88.60  ? 545 THR B CG2 1 
ATOM   2652 N N   . PHE A  1 546 ? 192.102 229.252 204.378 1.00 84.94  ? 546 PHE B N   1 
ATOM   2653 C CA  . PHE A  1 546 ? 190.966 229.090 203.467 1.00 86.68  ? 546 PHE B CA  1 
ATOM   2654 C C   . PHE A  1 546 ? 190.289 227.736 203.656 1.00 88.51  ? 546 PHE B C   1 
ATOM   2655 O O   . PHE A  1 546 ? 189.896 227.079 202.690 1.00 91.64  ? 546 PHE B O   1 
ATOM   2656 C CB  . PHE A  1 546 ? 191.392 229.279 202.009 1.00 87.61  ? 546 PHE B CB  1 
ATOM   2657 C CG  . PHE A  1 546 ? 192.447 230.328 201.812 1.00 92.09  ? 546 PHE B CG  1 
ATOM   2658 C CD1 . PHE A  1 546 ? 192.117 231.672 201.825 1.00 91.60  ? 546 PHE B CD1 1 
ATOM   2659 C CD2 . PHE A  1 546 ? 193.768 229.969 201.610 1.00 90.66  ? 546 PHE B CD2 1 
ATOM   2660 C CE1 . PHE A  1 546 ? 193.086 232.638 201.643 1.00 90.23  ? 546 PHE B CE1 1 
ATOM   2661 C CE2 . PHE A  1 546 ? 194.742 230.930 201.429 1.00 91.01  ? 546 PHE B CE2 1 
ATOM   2662 C CZ  . PHE A  1 546 ? 194.400 232.266 201.445 1.00 92.20  ? 546 PHE B CZ  1 
ATOM   2663 N N   . LEU A  1 547 ? 190.146 227.316 204.907 1.00 80.43  ? 547 LEU B N   1 
ATOM   2664 C CA  . LEU A  1 547 ? 189.594 226.006 205.234 1.00 79.22  ? 547 LEU B CA  1 
ATOM   2665 C C   . LEU A  1 547 ? 188.695 226.160 206.455 1.00 79.98  ? 547 LEU B C   1 
ATOM   2666 O O   . LEU A  1 547 ? 188.281 227.266 206.817 1.00 87.38  ? 547 LEU B O   1 
ATOM   2667 C CB  . LEU A  1 547 ? 190.713 224.980 205.463 1.00 79.50  ? 547 LEU B CB  1 
ATOM   2668 C CG  . LEU A  1 547 ? 191.289 224.277 204.238 1.00 76.71  ? 547 LEU B CG  1 
ATOM   2669 C CD1 . LEU A  1 547 ? 192.007 223.014 204.668 1.00 73.82  ? 547 LEU B CD1 1 
ATOM   2670 C CD2 . LEU A  1 547 ? 190.190 223.967 203.243 1.00 74.49  ? 547 LEU B CD2 1 
ATOM   2671 N N   . ARG A  1 548 ? 188.368 225.037 207.083 1.00 64.62  ? 548 ARG B N   1 
ATOM   2672 C CA  . ARG A  1 548 ? 187.571 225.012 208.297 1.00 69.61  ? 548 ARG B CA  1 
ATOM   2673 C C   . ARG A  1 548 ? 188.466 224.784 209.510 1.00 70.25  ? 548 ARG B C   1 
ATOM   2674 O O   . ARG A  1 548 ? 189.623 224.376 209.399 1.00 71.51  ? 548 ARG B O   1 
ATOM   2675 C CB  . ARG A  1 548 ? 186.497 223.929 208.211 1.00 66.58  ? 548 ARG B CB  1 
ATOM   2676 C CG  . ARG A  1 548 ? 185.360 224.096 209.208 1.00 68.53  ? 548 ARG B CG  1 
ATOM   2677 C CD  . ARG A  1 548 ? 184.229 223.116 208.959 1.00 66.85  ? 548 ARG B CD  1 
ATOM   2678 N NE  . ARG A  1 548 ? 184.701 221.740 208.867 1.00 69.01  ? 548 ARG B NE  1 
ATOM   2679 C CZ  . ARG A  1 548 ? 185.023 221.124 207.737 1.00 64.61  ? 548 ARG B CZ  1 
ATOM   2680 N NH1 . ARG A  1 548 ? 184.887 221.714 206.562 1.00 61.82  ? 548 ARG B NH1 1 
ATOM   2681 N NH2 . ARG A  1 548 ? 185.492 219.883 207.790 1.00 60.67  ? 548 ARG B NH2 1 
ATOM   2682 N N   . GLU A  1 549 ? 187.907 225.057 210.689 1.00 75.49  ? 549 GLU B N   1 
ATOM   2683 C CA  . GLU A  1 549 ? 188.700 224.974 211.907 1.00 78.96  ? 549 GLU B CA  1 
ATOM   2684 C C   . GLU A  1 549 ? 188.947 223.525 212.312 1.00 74.90  ? 549 GLU B C   1 
ATOM   2685 O O   . GLU A  1 549 ? 189.962 223.229 212.951 1.00 70.21  ? 549 GLU B O   1 
ATOM   2686 C CB  . GLU A  1 549 ? 188.018 225.804 213.009 1.00 79.98  ? 549 GLU B CB  1 
ATOM   2687 C CG  . GLU A  1 549 ? 188.423 225.592 214.488 1.00 79.00  ? 549 GLU B CG  1 
ATOM   2688 C CD  . GLU A  1 549 ? 188.096 224.228 215.068 1.00 78.24  ? 549 GLU B CD  1 
ATOM   2689 O OE1 . GLU A  1 549 ? 187.220 223.544 214.508 1.00 73.50  ? 549 GLU B OE1 1 
ATOM   2690 O OE2 . GLU A  1 549 ? 188.727 223.832 216.073 1.00 80.88  ? 549 GLU B OE2 1 
ATOM   2691 N N   . GLU A  1 550 ? 188.030 222.617 211.985 1.00 73.90  ? 550 GLU B N   1 
ATOM   2692 C CA  . GLU A  1 550 ? 188.175 221.202 212.298 1.00 73.73  ? 550 GLU B CA  1 
ATOM   2693 C C   . GLU A  1 550 ? 188.205 220.393 211.012 1.00 72.35  ? 550 GLU B C   1 
ATOM   2694 O O   . GLU A  1 550 ? 187.375 220.597 210.121 1.00 72.47  ? 550 GLU B O   1 
ATOM   2695 C CB  . GLU A  1 550 ? 187.032 220.691 213.177 1.00 73.46  ? 550 GLU B CB  1 
ATOM   2696 C CG  . GLU A  1 550 ? 187.295 219.328 213.825 1.00 75.78  ? 550 GLU B CG  1 
ATOM   2697 C CD  . GLU A  1 550 ? 186.157 218.881 214.729 1.00 79.36  ? 550 GLU B CD  1 
ATOM   2698 O OE1 . GLU A  1 550 ? 185.243 219.694 214.979 1.00 78.63  ? 550 GLU B OE1 1 
ATOM   2699 O OE2 . GLU A  1 550 ? 186.163 217.713 215.174 1.00 77.28  ? 550 GLU B OE2 1 
ATOM   2700 N N   . ILE A  1 551 ? 189.162 219.477 210.922 1.00 66.21  ? 551 ILE B N   1 
ATOM   2701 C CA  . ILE A  1 551 ? 189.297 218.591 209.772 1.00 67.70  ? 551 ILE B CA  1 
ATOM   2702 C C   . ILE A  1 551 ? 189.495 217.172 210.287 1.00 66.09  ? 551 ILE B C   1 
ATOM   2703 O O   . ILE A  1 551 ? 190.226 216.949 211.258 1.00 65.09  ? 551 ILE B O   1 
ATOM   2704 C CB  . ILE A  1 551 ? 190.461 219.016 208.851 1.00 63.02  ? 551 ILE B CB  1 
ATOM   2705 C CG1 . ILE A  1 551 ? 191.748 219.192 209.662 1.00 68.33  ? 551 ILE B CG1 1 
ATOM   2706 C CG2 . ILE A  1 551 ? 190.111 220.293 208.094 1.00 60.45  ? 551 ILE B CG2 1 
ATOM   2707 C CD1 . ILE A  1 551 ? 192.832 219.979 208.953 1.00 70.84  ? 551 ILE B CD1 1 
ATOM   2708 N N   . VAL A  1 552 ? 188.834 216.214 209.642 1.00 60.26  ? 552 VAL B N   1 
ATOM   2709 C CA  . VAL A  1 552 ? 188.913 214.821 210.057 1.00 58.28  ? 552 VAL B CA  1 
ATOM   2710 C C   . VAL A  1 552 ? 189.692 213.960 209.071 1.00 62.52  ? 552 VAL B C   1 
ATOM   2711 O O   . VAL A  1 552 ? 190.075 212.835 209.427 1.00 63.90  ? 552 VAL B O   1 
ATOM   2712 C CB  . VAL A  1 552 ? 187.509 214.225 210.291 1.00 53.00  ? 552 VAL B CB  1 
ATOM   2713 C CG1 . VAL A  1 552 ? 186.893 213.761 208.980 1.00 54.90  ? 552 VAL B CG1 1 
ATOM   2714 C CG2 . VAL A  1 552 ? 187.568 213.092 211.305 1.00 59.91  ? 552 VAL B CG2 1 
ATOM   2715 N N   . TYR A  1 553 ? 189.940 214.440 207.859 1.00 60.38  ? 553 TYR B N   1 
ATOM   2716 C CA  . TYR A  1 553 ? 190.712 213.662 206.905 1.00 62.45  ? 553 TYR B CA  1 
ATOM   2717 C C   . TYR A  1 553 ? 192.197 213.741 207.253 1.00 60.30  ? 553 TYR B C   1 
ATOM   2718 O O   . TYR A  1 553 ? 192.679 214.797 207.674 1.00 59.88  ? 553 TYR B O   1 
ATOM   2719 C CB  . TYR A  1 553 ? 190.458 214.161 205.484 1.00 54.85  ? 553 TYR B CB  1 
ATOM   2720 C CG  . TYR A  1 553 ? 189.078 213.796 204.986 1.00 53.94  ? 553 TYR B CG  1 
ATOM   2721 C CD1 . TYR A  1 553 ? 188.267 212.941 205.717 1.00 47.84  ? 553 TYR B CD1 1 
ATOM   2722 C CD2 . TYR A  1 553 ? 188.581 214.308 203.798 1.00 58.64  ? 553 TYR B CD2 1 
ATOM   2723 C CE1 . TYR A  1 553 ? 187.010 212.605 205.284 1.00 44.07  ? 553 TYR B CE1 1 
ATOM   2724 C CE2 . TYR A  1 553 ? 187.317 213.972 203.356 1.00 68.17  ? 553 TYR B CE2 1 
ATOM   2725 C CZ  . TYR A  1 553 ? 186.539 213.118 204.107 1.00 57.12  ? 553 TYR B CZ  1 
ATOM   2726 O OH  . TYR A  1 553 ? 185.279 212.771 203.688 1.00 53.59  ? 553 TYR B OH  1 
ATOM   2727 N N   . PRO A  1 554 ? 192.942 212.641 207.100 1.00 70.28  ? 554 PRO B N   1 
ATOM   2728 C CA  . PRO A  1 554 ? 194.317 212.609 207.632 1.00 73.63  ? 554 PRO B CA  1 
ATOM   2729 C C   . PRO A  1 554 ? 195.244 213.656 207.041 1.00 71.38  ? 554 PRO B C   1 
ATOM   2730 O O   . PRO A  1 554 ? 196.098 214.191 207.759 1.00 70.51  ? 554 PRO B O   1 
ATOM   2731 C CB  . PRO A  1 554 ? 194.782 211.186 207.295 1.00 73.25  ? 554 PRO B CB  1 
ATOM   2732 C CG  . PRO A  1 554 ? 193.939 210.776 206.132 1.00 71.98  ? 554 PRO B CG  1 
ATOM   2733 C CD  . PRO A  1 554 ? 192.601 211.410 206.367 1.00 69.44  ? 554 PRO B CD  1 
ATOM   2734 N N   . GLN A  1 555 ? 195.108 213.966 205.757 1.00 67.04  ? 555 GLN B N   1 
ATOM   2735 C CA  . GLN A  1 555 ? 196.011 214.878 205.070 1.00 68.36  ? 555 GLN B CA  1 
ATOM   2736 C C   . GLN A  1 555 ? 195.280 216.175 204.756 1.00 67.38  ? 555 GLN B C   1 
ATOM   2737 O O   . GLN A  1 555 ? 194.172 216.151 204.212 1.00 72.27  ? 555 GLN B O   1 
ATOM   2738 C CB  . GLN A  1 555 ? 196.550 214.247 203.785 1.00 68.18  ? 555 GLN B CB  1 
ATOM   2739 C CG  . GLN A  1 555 ? 198.037 214.459 203.565 1.00 69.58  ? 555 GLN B CG  1 
ATOM   2740 C CD  . GLN A  1 555 ? 198.882 213.417 204.270 1.00 72.08  ? 555 GLN B CD  1 
ATOM   2741 O OE1 . GLN A  1 555 ? 198.624 212.218 204.167 1.00 72.35  ? 555 GLN B OE1 1 
ATOM   2742 N NE2 . GLN A  1 555 ? 199.898 213.871 204.993 1.00 71.93  ? 555 GLN B NE2 1 
ATOM   2743 N N   . LYS A  1 556 ? 195.904 217.303 205.099 1.00 64.28  ? 556 LYS B N   1 
ATOM   2744 C CA  . LYS A  1 556 ? 195.284 218.598 204.851 1.00 61.60  ? 556 LYS B CA  1 
ATOM   2745 C C   . LYS A  1 556 ? 195.333 218.998 203.383 1.00 63.76  ? 556 LYS B C   1 
ATOM   2746 O O   . LYS A  1 556 ? 194.569 219.876 202.970 1.00 68.87  ? 556 LYS B O   1 
ATOM   2747 C CB  . LYS A  1 556 ? 195.957 219.675 205.702 1.00 67.97  ? 556 LYS B CB  1 
ATOM   2748 C CG  . LYS A  1 556 ? 195.046 220.832 206.071 1.00 66.51  ? 556 LYS B CG  1 
ATOM   2749 C CD  . LYS A  1 556 ? 195.759 221.832 206.965 1.00 68.67  ? 556 LYS B CD  1 
ATOM   2750 C CE  . LYS A  1 556 ? 196.246 221.179 208.247 1.00 68.22  ? 556 LYS B CE  1 
ATOM   2751 N NZ  . LYS A  1 556 ? 196.893 222.163 209.158 1.00 68.34  ? 556 LYS B NZ  1 
ATOM   2752 N N   . ALA A  1 557 ? 196.206 218.379 202.586 1.00 59.01  ? 557 ALA B N   1 
ATOM   2753 C CA  . ALA A  1 557 ? 196.288 218.718 201.170 1.00 62.41  ? 557 ALA B CA  1 
ATOM   2754 C C   . ALA A  1 557 ? 195.069 218.247 200.390 1.00 62.52  ? 557 ALA B C   1 
ATOM   2755 O O   . ALA A  1 557 ? 194.834 218.734 199.275 1.00 61.38  ? 557 ALA B O   1 
ATOM   2756 C CB  . ALA A  1 557 ? 197.557 218.123 200.560 1.00 58.99  ? 557 ALA B CB  1 
ATOM   2757 N N   . TYR A  1 558 ? 194.298 217.311 200.948 1.00 52.26  ? 558 TYR B N   1 
ATOM   2758 C CA  . TYR A  1 558 ? 193.100 216.830 200.270 1.00 47.60  ? 558 TYR B CA  1 
ATOM   2759 C C   . TYR A  1 558 ? 192.116 217.966 200.030 1.00 54.28  ? 558 TYR B C   1 
ATOM   2760 O O   . TYR A  1 558 ? 191.588 218.119 198.925 1.00 56.42  ? 558 TYR B O   1 
ATOM   2761 C CB  . TYR A  1 558 ? 192.442 215.720 201.090 1.00 49.31  ? 558 TYR B CB  1 
ATOM   2762 C CG  . TYR A  1 558 ? 193.240 214.442 201.160 1.00 53.30  ? 558 TYR B CG  1 
ATOM   2763 C CD1 . TYR A  1 558 ? 194.102 214.081 200.137 1.00 51.05  ? 558 TYR B CD1 1 
ATOM   2764 C CD2 . TYR A  1 558 ? 193.123 213.590 202.248 1.00 57.90  ? 558 TYR B CD2 1 
ATOM   2765 C CE1 . TYR A  1 558 ? 194.829 212.910 200.198 1.00 57.96  ? 558 TYR B CE1 1 
ATOM   2766 C CE2 . TYR A  1 558 ? 193.845 212.418 202.318 1.00 52.45  ? 558 TYR B CE2 1 
ATOM   2767 C CZ  . TYR A  1 558 ? 194.696 212.083 201.291 1.00 60.55  ? 558 TYR B CZ  1 
ATOM   2768 O OH  . TYR A  1 558 ? 195.417 210.915 201.360 1.00 65.90  ? 558 TYR B OH  1 
ATOM   2769 N N   . TYR A  1 559 ? 191.867 218.783 201.056 1.00 49.25  ? 559 TYR B N   1 
ATOM   2770 C CA  . TYR A  1 559 ? 190.939 219.899 200.904 1.00 44.88  ? 559 TYR B CA  1 
ATOM   2771 C C   . TYR A  1 559 ? 191.445 220.902 199.876 1.00 54.39  ? 559 TYR B C   1 
ATOM   2772 O O   . TYR A  1 559 ? 190.669 221.406 199.054 1.00 68.34  ? 559 TYR B O   1 
ATOM   2773 C CB  . TYR A  1 559 ? 190.719 220.598 202.245 1.00 42.43  ? 559 TYR B CB  1 
ATOM   2774 C CG  . TYR A  1 559 ? 190.245 219.717 203.378 1.00 40.83  ? 559 TYR B CG  1 
ATOM   2775 C CD1 . TYR A  1 559 ? 191.106 218.832 204.008 1.00 49.25  ? 559 TYR B CD1 1 
ATOM   2776 C CD2 . TYR A  1 559 ? 188.939 219.789 203.832 1.00 49.83  ? 559 TYR B CD2 1 
ATOM   2777 C CE1 . TYR A  1 559 ? 190.676 218.036 205.047 1.00 53.62  ? 559 TYR B CE1 1 
ATOM   2778 C CE2 . TYR A  1 559 ? 188.500 218.998 204.870 1.00 54.09  ? 559 TYR B CE2 1 
ATOM   2779 C CZ  . TYR A  1 559 ? 189.372 218.123 205.474 1.00 51.88  ? 559 TYR B CZ  1 
ATOM   2780 O OH  . TYR A  1 559 ? 188.937 217.331 206.510 1.00 51.02  ? 559 TYR B OH  1 
ATOM   2781 N N   . TYR A  1 560 ? 192.741 221.218 199.917 1.00 60.80  ? 560 TYR B N   1 
ATOM   2782 C CA  . TYR A  1 560 ? 193.285 222.222 199.010 1.00 63.94  ? 560 TYR B CA  1 
ATOM   2783 C C   . TYR A  1 560 ? 193.211 221.762 197.561 1.00 65.84  ? 560 TYR B C   1 
ATOM   2784 O O   . TYR A  1 560 ? 192.880 222.554 196.672 1.00 56.19  ? 560 TYR B O   1 
ATOM   2785 C CB  . TYR A  1 560 ? 194.723 222.559 199.398 1.00 60.73  ? 560 TYR B CB  1 
ATOM   2786 C CG  . TYR A  1 560 ? 194.842 223.154 200.778 1.00 60.48  ? 560 TYR B CG  1 
ATOM   2787 C CD1 . TYR A  1 560 ? 194.261 224.376 201.077 1.00 65.54  ? 560 TYR B CD1 1 
ATOM   2788 C CD2 . TYR A  1 560 ? 195.533 222.494 201.783 1.00 60.45  ? 560 TYR B CD2 1 
ATOM   2789 C CE1 . TYR A  1 560 ? 194.362 224.924 202.336 1.00 65.74  ? 560 TYR B CE1 1 
ATOM   2790 C CE2 . TYR A  1 560 ? 195.639 223.034 203.048 1.00 63.67  ? 560 TYR B CE2 1 
ATOM   2791 C CZ  . TYR A  1 560 ? 195.053 224.250 203.319 1.00 67.78  ? 560 TYR B CZ  1 
ATOM   2792 O OH  . TYR A  1 560 ? 195.156 224.795 204.577 1.00 67.88  ? 560 TYR B OH  1 
ATOM   2793 N N   . CYS A  1 561 ? 193.517 220.490 197.299 1.00 65.10  ? 561 CYS B N   1 
ATOM   2794 C CA  . CYS A  1 561 ? 193.377 219.994 195.934 1.00 65.68  ? 561 CYS B CA  1 
ATOM   2795 C C   . CYS A  1 561 ? 191.912 219.880 195.534 1.00 69.62  ? 561 CYS B C   1 
ATOM   2796 O O   . CYS A  1 561 ? 191.563 220.137 194.373 1.00 75.39  ? 561 CYS B O   1 
ATOM   2797 C CB  . CYS A  1 561 ? 194.083 218.648 195.780 1.00 65.17  ? 561 CYS B CB  1 
ATOM   2798 S SG  . CYS A  1 561 ? 193.117 217.226 196.316 1.00 88.11  ? 561 CYS B SG  1 
ATOM   2799 N N   . ALA A  1 562 ? 191.040 219.524 196.482 1.00 51.65  ? 562 ALA B N   1 
ATOM   2800 C CA  . ALA A  1 562 ? 189.623 219.388 196.180 1.00 51.52  ? 562 ALA B CA  1 
ATOM   2801 C C   . ALA A  1 562 ? 188.983 220.724 195.846 1.00 50.71  ? 562 ALA B C   1 
ATOM   2802 O O   . ALA A  1 562 ? 188.035 220.764 195.066 1.00 63.92  ? 562 ALA B O   1 
ATOM   2803 C CB  . ALA A  1 562 ? 188.896 218.738 197.353 1.00 49.15  ? 562 ALA B CB  1 
ATOM   2804 N N   . ILE A  1 563 ? 189.469 221.820 196.428 1.00 43.02  ? 563 ILE B N   1 
ATOM   2805 C CA  . ILE A  1 563 ? 188.906 223.132 196.111 1.00 43.39  ? 563 ILE B CA  1 
ATOM   2806 C C   . ILE A  1 563 ? 189.152 223.477 194.645 1.00 52.48  ? 563 ILE B C   1 
ATOM   2807 O O   . ILE A  1 563 ? 188.236 223.886 193.917 1.00 52.81  ? 563 ILE B O   1 
ATOM   2808 C CB  . ILE A  1 563 ? 189.487 224.204 197.048 1.00 40.42  ? 563 ILE B CB  1 
ATOM   2809 C CG1 . ILE A  1 563 ? 188.914 224.044 198.454 1.00 40.17  ? 563 ILE B CG1 1 
ATOM   2810 C CG2 . ILE A  1 563 ? 189.190 225.592 196.515 1.00 46.20  ? 563 ILE B CG2 1 
ATOM   2811 C CD1 . ILE A  1 563 ? 189.495 225.006 199.456 1.00 46.66  ? 563 ILE B CD1 1 
ATOM   2812 N N   . ILE A  1 564 ? 190.395 223.305 194.188 1.00 55.59  ? 564 ILE B N   1 
ATOM   2813 C CA  . ILE A  1 564 ? 190.724 223.571 192.790 1.00 57.23  ? 564 ILE B CA  1 
ATOM   2814 C C   . ILE A  1 564 ? 189.964 222.620 191.878 1.00 55.71  ? 564 ILE B C   1 
ATOM   2815 O O   . ILE A  1 564 ? 189.443 223.020 190.824 1.00 54.42  ? 564 ILE B O   1 
ATOM   2816 C CB  . ILE A  1 564 ? 192.246 223.472 192.574 1.00 49.98  ? 564 ILE B CB  1 
ATOM   2817 C CG1 . ILE A  1 564 ? 192.962 224.615 193.295 1.00 56.81  ? 564 ILE B CG1 1 
ATOM   2818 C CG2 . ILE A  1 564 ? 192.581 223.482 191.092 1.00 48.34  ? 564 ILE B CG2 1 
ATOM   2819 C CD1 . ILE A  1 564 ? 192.585 225.989 192.787 1.00 53.80  ? 564 ILE B CD1 1 
ATOM   2820 N N   . GLU A  1 565 ? 189.891 221.343 192.266 1.00 54.14  ? 565 GLU B N   1 
ATOM   2821 C CA  . GLU A  1 565 ? 189.144 220.372 191.477 1.00 51.82  ? 565 GLU B CA  1 
ATOM   2822 C C   . GLU A  1 565 ? 187.678 220.765 191.369 1.00 51.48  ? 565 GLU B C   1 
ATOM   2823 O O   . GLU A  1 565 ? 187.078 220.671 190.292 1.00 59.11  ? 565 GLU B O   1 
ATOM   2824 C CB  . GLU A  1 565 ? 189.289 218.985 192.100 1.00 45.77  ? 565 GLU B CB  1 
ATOM   2825 C CG  . GLU A  1 565 ? 188.563 217.885 191.358 1.00 53.39  ? 565 GLU B CG  1 
ATOM   2826 C CD  . GLU A  1 565 ? 187.177 217.647 191.905 1.00 54.06  ? 565 GLU B CD  1 
ATOM   2827 O OE1 . GLU A  1 565 ? 186.780 218.366 192.844 1.00 55.71  ? 565 GLU B OE1 1 
ATOM   2828 O OE2 . GLU A  1 565 ? 186.486 216.739 191.404 1.00 52.38  ? 565 GLU B OE2 1 
ATOM   2829 N N   . ASP A  1 566 ? 187.084 221.208 192.477 1.00 46.89  ? 566 ASP B N   1 
ATOM   2830 C CA  . ASP A  1 566 ? 185.690 221.619 192.462 1.00 43.14  ? 566 ASP B CA  1 
ATOM   2831 C C   . ASP A  1 566 ? 185.486 222.825 191.564 1.00 51.43  ? 566 ASP B C   1 
ATOM   2832 O O   . ASP A  1 566 ? 184.498 222.890 190.838 1.00 57.97  ? 566 ASP B O   1 
ATOM   2833 C CB  . ASP A  1 566 ? 185.206 221.921 193.878 1.00 43.07  ? 566 ASP B CB  1 
ATOM   2834 C CG  . ASP A  1 566 ? 183.696 222.010 193.968 1.00 49.20  ? 566 ASP B CG  1 
ATOM   2835 O OD1 . ASP A  1 566 ? 183.109 222.918 193.344 1.00 56.29  ? 566 ASP B OD1 1 
ATOM   2836 O OD2 . ASP A  1 566 ? 183.089 221.164 194.652 1.00 55.91  ? 566 ASP B OD2 1 
ATOM   2837 N N   . VAL A  1 567 ? 186.409 223.787 191.589 1.00 52.95  ? 567 VAL B N   1 
ATOM   2838 C CA  . VAL A  1 567 ? 186.258 224.958 190.725 1.00 57.12  ? 567 VAL B CA  1 
ATOM   2839 C C   . VAL A  1 567 ? 186.289 224.544 189.255 1.00 51.82  ? 567 VAL B C   1 
ATOM   2840 O O   . VAL A  1 567 ? 185.384 224.878 188.467 1.00 52.18  ? 567 VAL B O   1 
ATOM   2841 C CB  . VAL A  1 567 ? 187.347 225.998 191.038 1.00 55.35  ? 567 VAL B CB  1 
ATOM   2842 C CG1 . VAL A  1 567 ? 187.385 227.066 189.958 1.00 55.40  ? 567 VAL B CG1 1 
ATOM   2843 C CG2 . VAL A  1 567 ? 187.109 226.620 192.403 1.00 53.40  ? 567 VAL B CG2 1 
ATOM   2844 N N   . ILE A  1 568 ? 187.319 223.784 188.871 1.00 48.28  ? 568 ILE B N   1 
ATOM   2845 C CA  . ILE A  1 568 ? 187.477 223.444 187.460 1.00 52.66  ? 568 ILE B CA  1 
ATOM   2846 C C   . ILE A  1 568 ? 186.316 222.578 186.985 1.00 54.64  ? 568 ILE B C   1 
ATOM   2847 O O   . ILE A  1 568 ? 185.731 222.833 185.925 1.00 58.46  ? 568 ILE B O   1 
ATOM   2848 C CB  . ILE A  1 568 ? 188.846 222.782 187.199 1.00 49.54  ? 568 ILE B CB  1 
ATOM   2849 C CG1 . ILE A  1 568 ? 189.018 221.496 188.005 1.00 51.52  ? 568 ILE B CG1 1 
ATOM   2850 C CG2 . ILE A  1 568 ? 189.973 223.750 187.518 1.00 50.64  ? 568 ILE B CG2 1 
ATOM   2851 C CD1 . ILE A  1 568 ? 190.227 220.684 187.604 1.00 50.83  ? 568 ILE B CD1 1 
ATOM   2852 N N   . LEU A  1 569 ? 185.925 221.577 187.771 1.00 49.56  ? 569 LEU B N   1 
ATOM   2853 C CA  . LEU A  1 569 ? 184.830 220.706 187.380 1.00 46.85  ? 569 LEU B CA  1 
ATOM   2854 C C   . LEU A  1 569 ? 183.466 221.358 187.550 1.00 48.30  ? 569 LEU B C   1 
ATOM   2855 O O   . LEU A  1 569 ? 182.523 220.948 186.878 1.00 50.81  ? 569 LEU B O   1 
ATOM   2856 C CB  . LEU A  1 569 ? 184.892 219.396 188.166 1.00 50.57  ? 569 LEU B CB  1 
ATOM   2857 C CG  . LEU A  1 569 ? 186.033 218.483 187.716 1.00 46.38  ? 569 LEU B CG  1 
ATOM   2858 C CD1 . LEU A  1 569 ? 185.914 217.109 188.340 1.00 48.64  ? 569 LEU B CD1 1 
ATOM   2859 C CD2 . LEU A  1 569 ? 186.071 218.386 186.201 1.00 45.79  ? 569 LEU B CD2 1 
ATOM   2860 N N   . ARG A  1 570 ? 183.349 222.389 188.382 1.00 53.39  ? 570 ARG B N   1 
ATOM   2861 C CA  . ARG A  1 570 ? 182.123 223.155 188.527 1.00 50.33  ? 570 ARG B CA  1 
ATOM   2862 C C   . ARG A  1 570 ? 181.856 224.019 187.315 1.00 55.69  ? 570 ARG B C   1 
ATOM   2863 O O   . ARG A  1 570 ? 180.694 224.278 186.985 1.00 52.56  ? 570 ARG B O   1 
ATOM   2864 C CB  . ARG A  1 570 ? 182.213 224.042 189.770 1.00 45.24  ? 570 ARG B CB  1 
ATOM   2865 C CG  . ARG A  1 570 ? 180.912 224.257 190.505 1.00 47.10  ? 570 ARG B CG  1 
ATOM   2866 C CD  . ARG A  1 570 ? 180.033 223.030 190.461 1.00 52.26  ? 570 ARG B CD  1 
ATOM   2867 N NE  . ARG A  1 570 ? 179.152 222.981 191.619 1.00 57.04  ? 570 ARG B NE  1 
ATOM   2868 C CZ  . ARG A  1 570 ? 178.008 222.315 191.667 1.00 58.14  ? 570 ARG B CZ  1 
ATOM   2869 N NH1 . ARG A  1 570 ? 177.557 221.642 190.622 1.00 59.17  ? 570 ARG B NH1 1 
ATOM   2870 N NH2 . ARG A  1 570 ? 177.299 222.325 192.791 1.00 60.64  ? 570 ARG B NH2 1 
ATOM   2871 N N   . PHE A  1 571 ? 182.909 224.500 186.663 1.00 63.79  ? 571 PHE B N   1 
ATOM   2872 C CA  . PHE A  1 571 ? 182.676 225.124 185.365 1.00 61.98  ? 571 PHE B CA  1 
ATOM   2873 C C   . PHE A  1 571 ? 182.506 224.088 184.254 1.00 57.52  ? 571 PHE B C   1 
ATOM   2874 O O   . PHE A  1 571 ? 181.636 224.241 183.377 1.00 56.45  ? 571 PHE B O   1 
ATOM   2875 C CB  . PHE A  1 571 ? 183.812 226.094 185.041 1.00 60.95  ? 571 PHE B CB  1 
ATOM   2876 C CG  . PHE A  1 571 ? 183.710 227.392 185.783 1.00 58.02  ? 571 PHE B CG  1 
ATOM   2877 C CD1 . PHE A  1 571 ? 184.146 227.491 187.092 1.00 54.35  ? 571 PHE B CD1 1 
ATOM   2878 C CD2 . PHE A  1 571 ? 183.151 228.505 185.183 1.00 60.17  ? 571 PHE B CD2 1 
ATOM   2879 C CE1 . PHE A  1 571 ? 184.041 228.679 187.783 1.00 57.10  ? 571 PHE B CE1 1 
ATOM   2880 C CE2 . PHE A  1 571 ? 183.044 229.696 185.868 1.00 66.87  ? 571 PHE B CE2 1 
ATOM   2881 C CZ  . PHE A  1 571 ? 183.490 229.783 187.171 1.00 64.98  ? 571 PHE B CZ  1 
ATOM   2882 N N   . ALA A  1 572 ? 183.304 223.015 184.306 1.00 63.46  ? 572 ALA B N   1 
ATOM   2883 C CA  . ALA A  1 572 ? 183.289 222.017 183.245 1.00 68.13  ? 572 ALA B CA  1 
ATOM   2884 C C   . ALA A  1 572 ? 181.947 221.300 183.157 1.00 70.61  ? 572 ALA B C   1 
ATOM   2885 O O   . ALA A  1 572 ? 181.422 221.104 182.059 1.00 72.08  ? 572 ALA B O   1 
ATOM   2886 C CB  . ALA A  1 572 ? 184.420 221.012 183.458 1.00 68.03  ? 572 ALA B CB  1 
ATOM   2887 N N   . TRP A  1 573 ? 181.379 220.892 184.298 1.00 68.81  ? 573 TRP B N   1 
ATOM   2888 C CA  . TRP A  1 573 ? 180.140 220.122 184.282 1.00 69.00  ? 573 TRP B CA  1 
ATOM   2889 C C   . TRP A  1 573 ? 179.004 220.925 183.672 1.00 68.28  ? 573 TRP B C   1 
ATOM   2890 O O   . TRP A  1 573 ? 178.239 220.409 182.846 1.00 66.10  ? 573 TRP B O   1 
ATOM   2891 C CB  . TRP A  1 573 ? 179.782 219.668 185.700 1.00 67.37  ? 573 TRP B CB  1 
ATOM   2892 C CG  . TRP A  1 573 ? 178.900 220.614 186.472 1.00 71.10  ? 573 TRP B CG  1 
ATOM   2893 C CD1 . TRP A  1 573 ? 179.283 221.762 187.092 1.00 71.68  ? 573 TRP B CD1 1 
ATOM   2894 C CD2 . TRP A  1 573 ? 177.487 220.494 186.691 1.00 70.97  ? 573 TRP B CD2 1 
ATOM   2895 N NE1 . TRP A  1 573 ? 178.204 222.365 187.691 1.00 68.46  ? 573 TRP B NE1 1 
ATOM   2896 C CE2 . TRP A  1 573 ? 177.088 221.606 187.458 1.00 66.99  ? 573 TRP B CE2 1 
ATOM   2897 C CE3 . TRP A  1 573 ? 176.524 219.554 186.316 1.00 67.97  ? 573 TRP B CE3 1 
ATOM   2898 C CZ2 . TRP A  1 573 ? 175.768 221.803 187.858 1.00 59.19  ? 573 TRP B CZ2 1 
ATOM   2899 C CZ3 . TRP A  1 573 ? 175.214 219.752 186.713 1.00 67.91  ? 573 TRP B CZ3 1 
ATOM   2900 C CH2 . TRP A  1 573 ? 174.849 220.867 187.476 1.00 62.98  ? 573 TRP B CH2 1 
ATOM   2901 N N   . THR A  1 574 ? 178.890 222.197 184.058 1.00 72.06  ? 574 THR B N   1 
ATOM   2902 C CA  . THR A  1 574 ? 177.912 223.074 183.436 1.00 75.53  ? 574 THR B CA  1 
ATOM   2903 C C   . THR A  1 574 ? 178.128 223.112 181.933 1.00 81.16  ? 574 THR B C   1 
ATOM   2904 O O   . THR A  1 574 ? 177.291 222.615 181.170 1.00 75.09  ? 574 THR B O   1 
ATOM   2905 C CB  . THR A  1 574 ? 177.998 224.476 184.040 1.00 72.27  ? 574 THR B CB  1 
ATOM   2906 O OG1 . THR A  1 574 ? 179.373 224.834 184.230 1.00 73.77  ? 574 THR B OG1 1 
ATOM   2907 C CG2 . THR A  1 574 ? 177.270 224.527 185.373 1.00 73.11  ? 574 THR B CG2 1 
ATOM   2908 N N   . ILE A  1 575 ? 179.306 223.594 181.506 1.00 86.78  ? 575 ILE B N   1 
ATOM   2909 C CA  . ILE A  1 575 ? 179.533 223.852 180.084 1.00 82.18  ? 575 ILE B CA  1 
ATOM   2910 C C   . ILE A  1 575 ? 179.397 222.570 179.267 1.00 79.16  ? 575 ILE B C   1 
ATOM   2911 O O   . ILE A  1 575 ? 179.138 222.612 178.057 1.00 74.98  ? 575 ILE B O   1 
ATOM   2912 C CB  . ILE A  1 575 ? 180.906 224.521 179.871 1.00 78.88  ? 575 ILE B CB  1 
ATOM   2913 C CG1 . ILE A  1 575 ? 181.105 224.913 178.405 1.00 82.20  ? 575 ILE B CG1 1 
ATOM   2914 C CG2 . ILE A  1 575 ? 182.027 223.595 180.281 1.00 74.02  ? 575 ILE B CG2 1 
ATOM   2915 C CD1 . ILE A  1 575 ? 182.246 225.884 178.184 1.00 79.39  ? 575 ILE B CD1 1 
ATOM   2916 N N   . GLN A  1 576 ? 179.538 221.409 179.910 1.00 77.12  ? 576 GLN B N   1 
ATOM   2917 C CA  . GLN A  1 576 ? 179.511 220.176 179.134 1.00 83.18  ? 576 GLN B CA  1 
ATOM   2918 C C   . GLN A  1 576 ? 178.121 219.549 179.061 1.00 81.33  ? 576 GLN B C   1 
ATOM   2919 O O   . GLN A  1 576 ? 177.684 219.165 177.971 1.00 83.53  ? 576 GLN B O   1 
ATOM   2920 C CB  . GLN A  1 576 ? 180.520 219.163 179.691 1.00 79.30  ? 576 GLN B CB  1 
ATOM   2921 C CG  . GLN A  1 576 ? 180.201 218.580 181.055 1.00 77.13  ? 576 GLN B CG  1 
ATOM   2922 C CD  . GLN A  1 576 ? 179.697 217.157 180.965 1.00 77.73  ? 576 GLN B CD  1 
ATOM   2923 O OE1 . GLN A  1 576 ? 179.823 216.510 179.930 1.00 78.23  ? 576 GLN B OE1 1 
ATOM   2924 N NE2 . GLN A  1 576 ? 179.156 216.651 182.059 1.00 78.68  ? 576 GLN B NE2 1 
ATOM   2925 N N   . ILE A  1 577 ? 177.407 219.420 180.182 1.00 76.12  ? 577 ILE B N   1 
ATOM   2926 C CA  . ILE A  1 577 ? 176.152 218.687 180.169 1.00 80.84  ? 577 ILE B CA  1 
ATOM   2927 C C   . ILE A  1 577 ? 174.946 219.563 180.486 1.00 79.73  ? 577 ILE B C   1 
ATOM   2928 O O   . ILE A  1 577 ? 173.845 219.257 180.015 1.00 75.90  ? 577 ILE B O   1 
ATOM   2929 C CB  . ILE A  1 577 ? 176.185 217.463 181.107 1.00 76.96  ? 577 ILE B CB  1 
ATOM   2930 C CG1 . ILE A  1 577 ? 175.275 216.369 180.554 1.00 75.24  ? 577 ILE B CG1 1 
ATOM   2931 C CG2 . ILE A  1 577 ? 175.658 217.828 182.476 1.00 75.19  ? 577 ILE B CG2 1 
ATOM   2932 C CD1 . ILE A  1 577 ? 175.847 215.644 179.356 1.00 78.26  ? 577 ILE B CD1 1 
ATOM   2933 N N   . SER A  1 578 ? 175.098 220.631 181.278 1.00 83.06  ? 578 SER B N   1 
ATOM   2934 C CA  . SER A  1 578 ? 173.932 221.468 181.511 1.00 81.46  ? 578 SER B CA  1 
ATOM   2935 C C   . SER A  1 578 ? 173.497 222.131 180.220 1.00 87.39  ? 578 SER B C   1 
ATOM   2936 O O   . SER A  1 578 ? 172.321 222.477 180.068 1.00 89.25  ? 578 SER B O   1 
ATOM   2937 C CB  . SER A  1 578 ? 174.224 222.510 182.591 1.00 84.42  ? 578 SER B CB  1 
ATOM   2938 O OG  . SER A  1 578 ? 174.339 221.897 183.864 1.00 85.59  ? 578 SER B OG  1 
ATOM   2939 N N   . ILE A  1 579 ? 174.431 222.285 179.285 1.00 92.36  ? 579 ILE B N   1 
ATOM   2940 C CA  . ILE A  1 579 ? 174.170 222.693 177.914 1.00 86.94  ? 579 ILE B CA  1 
ATOM   2941 C C   . ILE A  1 579 ? 174.846 221.655 177.029 1.00 87.04  ? 579 ILE B C   1 
ATOM   2942 O O   . ILE A  1 579 ? 175.329 220.632 177.528 1.00 89.89  ? 579 ILE B O   1 
ATOM   2943 C CB  . ILE A  1 579 ? 174.699 224.108 177.630 1.00 88.89  ? 579 ILE B CB  1 
ATOM   2944 C CG1 . ILE A  1 579 ? 174.607 224.976 178.883 1.00 86.27  ? 579 ILE B CG1 1 
ATOM   2945 C CG2 . ILE A  1 579 ? 173.881 224.748 176.544 1.00 90.85  ? 579 ILE B CG2 1 
ATOM   2946 C CD1 . ILE A  1 579 ? 173.196 225.347 179.254 1.00 85.13  ? 579 ILE B CD1 1 
ATOM   2947 N N   . THR A  1 580 ? 174.828 221.878 175.712 1.00 94.53  ? 580 THR B N   1 
ATOM   2948 C CA  . THR A  1 580 ? 175.568 221.076 174.739 1.00 100.20 ? 580 THR B CA  1 
ATOM   2949 C C   . THR A  1 580 ? 174.923 219.704 174.576 1.00 97.79  ? 580 THR B C   1 
ATOM   2950 O O   . THR A  1 580 ? 175.311 218.920 173.703 1.00 94.74  ? 580 THR B O   1 
ATOM   2951 C CB  . THR A  1 580 ? 177.043 220.950 175.145 1.00 97.47  ? 580 THR B CB  1 
ATOM   2952 O OG1 . THR A  1 580 ? 177.503 222.200 175.673 1.00 97.36  ? 580 THR B OG1 1 
ATOM   2953 C CG2 . THR A  1 580 ? 177.901 220.584 173.953 1.00 92.21  ? 580 THR B CG2 1 
ATOM   2954 N N   . SER A  1 581 ? 173.921 219.415 175.403 1.00 95.41  ? 581 SER B N   1 
ATOM   2955 C CA  . SER A  1 581 ? 173.085 218.238 175.248 1.00 93.83  ? 581 SER B CA  1 
ATOM   2956 C C   . SER A  1 581 ? 171.615 218.604 175.119 1.00 94.14  ? 581 SER B C   1 
ATOM   2957 O O   . SER A  1 581 ? 170.786 217.721 174.871 1.00 92.87  ? 581 SER B O   1 
ATOM   2958 C CB  . SER A  1 581 ? 173.291 217.276 176.424 1.00 91.55  ? 581 SER B CB  1 
ATOM   2959 O OG  . SER A  1 581 ? 174.656 217.206 176.794 1.00 89.27  ? 581 SER B OG  1 
ATOM   2960 N N   . THR A  1 582 ? 171.273 219.881 175.294 1.00 93.08  ? 582 THR B N   1 
ATOM   2961 C CA  . THR A  1 582 ? 169.971 220.411 174.930 1.00 91.15  ? 582 THR B CA  1 
ATOM   2962 C C   . THR A  1 582 ? 170.047 221.427 173.801 1.00 95.52  ? 582 THR B C   1 
ATOM   2963 O O   . THR A  1 582 ? 168.999 221.880 173.329 1.00 94.49  ? 582 THR B O   1 
ATOM   2964 C CB  . THR A  1 582 ? 169.287 221.056 176.146 1.00 90.36  ? 582 THR B CB  1 
ATOM   2965 O OG1 . THR A  1 582 ? 168.138 221.794 175.715 1.00 93.35  ? 582 THR B OG1 1 
ATOM   2966 C CG2 . THR A  1 582 ? 170.248 221.987 176.865 1.00 89.52  ? 582 THR B CG2 1 
ATOM   2967 N N   . THR A  1 583 ? 171.251 221.809 173.373 1.00 112.50 ? 583 THR B N   1 
ATOM   2968 C CA  . THR A  1 583 ? 171.467 222.598 172.168 1.00 113.09 ? 583 THR B CA  1 
ATOM   2969 C C   . THR A  1 583 ? 172.642 222.002 171.408 1.00 112.78 ? 583 THR B C   1 
ATOM   2970 O O   . THR A  1 583 ? 173.562 221.445 172.013 1.00 111.09 ? 583 THR B O   1 
ATOM   2971 C CB  . THR A  1 583 ? 171.748 224.075 172.477 1.00 111.60 ? 583 THR B CB  1 
ATOM   2972 O OG1 . THR A  1 583 ? 171.892 224.797 171.248 1.00 112.20 ? 583 THR B OG1 1 
ATOM   2973 C CG2 . THR A  1 583 ? 173.026 224.216 173.263 1.00 107.95 ? 583 THR B CG2 1 
ATOM   2974 N N   . LEU A  1 584 ? 172.597 222.095 170.079 1.00 122.17 ? 584 LEU B N   1 
ATOM   2975 C CA  . LEU A  1 584 ? 173.693 221.616 169.239 1.00 123.86 ? 584 LEU B CA  1 
ATOM   2976 C C   . LEU A  1 584 ? 174.510 222.819 168.773 1.00 122.25 ? 584 LEU B C   1 
ATOM   2977 O O   . LEU A  1 584 ? 174.455 223.238 167.617 1.00 118.87 ? 584 LEU B O   1 
ATOM   2978 C CB  . LEU A  1 584 ? 173.154 220.798 168.068 1.00 122.76 ? 584 LEU B CB  1 
ATOM   2979 C CG  . LEU A  1 584 ? 174.185 220.122 167.158 1.00 123.29 ? 584 LEU B CG  1 
ATOM   2980 C CD1 . LEU A  1 584 ? 175.138 219.259 167.969 1.00 120.55 ? 584 LEU B CD1 1 
ATOM   2981 C CD2 . LEU A  1 584 ? 173.494 219.297 166.084 1.00 121.65 ? 584 LEU B CD2 1 
ATOM   2982 N N   . LEU A  1 585 ? 175.273 223.392 169.703 1.00 117.06 ? 585 LEU B N   1 
ATOM   2983 C CA  . LEU A  1 585 ? 176.184 224.466 169.326 1.00 116.42 ? 585 LEU B CA  1 
ATOM   2984 C C   . LEU A  1 585 ? 177.447 223.884 168.692 1.00 114.70 ? 585 LEU B C   1 
ATOM   2985 O O   . LEU A  1 585 ? 177.781 224.254 167.559 1.00 114.05 ? 585 LEU B O   1 
ATOM   2986 C CB  . LEU A  1 585 ? 176.509 225.359 170.532 1.00 116.74 ? 585 LEU B CB  1 
ATOM   2987 C CG  . LEU A  1 585 ? 177.507 226.512 170.370 1.00 116.87 ? 585 LEU B CG  1 
ATOM   2988 C CD1 . LEU A  1 585 ? 177.107 227.679 171.256 1.00 112.34 ? 585 LEU B CD1 1 
ATOM   2989 C CD2 . LEU A  1 585 ? 178.931 226.078 170.696 1.00 116.63 ? 585 LEU B CD2 1 
ATOM   2990 N N   . PRO A  1 586 ? 178.189 222.973 169.370 1.00 112.30 ? 586 PRO B N   1 
ATOM   2991 C CA  . PRO A  1 586 ? 179.381 222.404 168.732 1.00 113.92 ? 586 PRO B CA  1 
ATOM   2992 C C   . PRO A  1 586 ? 179.127 221.054 168.076 1.00 115.01 ? 586 PRO B C   1 
ATOM   2993 O O   . PRO A  1 586 ? 178.269 220.287 168.524 1.00 112.53 ? 586 PRO B O   1 
ATOM   2994 C CB  . PRO A  1 586 ? 180.365 222.283 169.900 1.00 112.84 ? 586 PRO B CB  1 
ATOM   2995 C CG  . PRO A  1 586 ? 179.485 222.094 171.116 1.00 113.63 ? 586 PRO B CG  1 
ATOM   2996 C CD  . PRO A  1 586 ? 178.062 222.472 170.752 1.00 111.80 ? 586 PRO B CD  1 
ATOM   2997 N N   . HIS A  1 587 ? 179.869 220.756 167.007 1.00 110.32 ? 587 HIS B N   1 
ATOM   2998 C CA  . HIS A  1 587 ? 179.829 219.411 166.440 1.00 109.37 ? 587 HIS B CA  1 
ATOM   2999 C C   . HIS A  1 587 ? 180.445 218.397 167.396 1.00 105.92 ? 587 HIS B C   1 
ATOM   3000 O O   . HIS A  1 587 ? 179.941 217.276 167.532 1.00 104.38 ? 587 HIS B O   1 
ATOM   3001 C CB  . HIS A  1 587 ? 180.547 219.383 165.092 1.00 107.68 ? 587 HIS B CB  1 
ATOM   3002 C CG  . HIS A  1 587 ? 180.403 218.086 164.358 1.00 108.13 ? 587 HIS B CG  1 
ATOM   3003 N ND1 . HIS A  1 587 ? 179.452 217.145 164.690 1.00 109.56 ? 587 HIS B ND1 1 
ATOM   3004 C CD2 . HIS A  1 587 ? 181.092 217.571 163.312 1.00 106.94 ? 587 HIS B CD2 1 
ATOM   3005 C CE1 . HIS A  1 587 ? 179.560 216.107 163.879 1.00 108.14 ? 587 HIS B CE1 1 
ATOM   3006 N NE2 . HIS A  1 587 ? 180.547 216.341 163.033 1.00 107.68 ? 587 HIS B NE2 1 
ATOM   3007 N N   . SER A  1 588 ? 181.533 218.772 168.067 1.00 88.99  ? 588 SER B N   1 
ATOM   3008 C CA  . SER A  1 588 ? 182.219 217.927 169.041 1.00 90.76  ? 588 SER B CA  1 
ATOM   3009 C C   . SER A  1 588 ? 181.528 217.895 170.384 1.00 88.58  ? 588 SER B C   1 
ATOM   3010 O O   . SER A  1 588 ? 182.128 217.424 171.368 1.00 90.12  ? 588 SER B O   1 
ATOM   3011 C CB  . SER A  1 588 ? 183.663 218.398 169.216 1.00 90.60  ? 588 SER B CB  1 
ATOM   3012 O OG  . SER A  1 588 ? 183.795 219.198 170.377 1.00 88.51  ? 588 SER B OG  1 
ATOM   3013 N N   . GLY A  1 589 ? 180.291 218.392 170.438 1.00 87.00  ? 589 GLY B N   1 
ATOM   3014 C CA  . GLY A  1 589 ? 179.559 218.404 171.690 1.00 91.89  ? 589 GLY B CA  1 
ATOM   3015 C C   . GLY A  1 589 ? 179.362 217.023 172.278 1.00 93.56  ? 589 GLY B C   1 
ATOM   3016 O O   . GLY A  1 589 ? 179.420 216.851 173.497 1.00 96.24  ? 589 GLY B O   1 
ATOM   3017 N N   . ASP A  1 590 ? 179.128 216.023 171.426 1.00 82.08  ? 590 ASP B N   1 
ATOM   3018 C CA  . ASP A  1 590 ? 178.990 214.656 171.914 1.00 78.12  ? 590 ASP B CA  1 
ATOM   3019 C C   . ASP A  1 590 ? 180.279 214.179 172.571 1.00 76.55  ? 590 ASP B C   1 
ATOM   3020 O O   . ASP A  1 590 ? 180.250 213.566 173.644 1.00 79.01  ? 590 ASP B O   1 
ATOM   3021 C CB  . ASP A  1 590 ? 178.594 213.730 170.766 1.00 78.62  ? 590 ASP B CB  1 
ATOM   3022 C CG  . ASP A  1 590 ? 177.362 214.210 170.032 1.00 85.02  ? 590 ASP B CG  1 
ATOM   3023 O OD1 . ASP A  1 590 ? 177.461 214.487 168.819 1.00 90.84  ? 590 ASP B OD1 1 
ATOM   3024 O OD2 . ASP A  1 590 ? 176.293 214.312 170.670 1.00 79.69  ? 590 ASP B OD2 1 
ATOM   3025 N N   . ILE A  1 591 ? 181.424 214.461 171.943 1.00 72.02  ? 591 ILE B N   1 
ATOM   3026 C CA  . ILE A  1 591 ? 182.705 214.067 172.525 1.00 74.96  ? 591 ILE B CA  1 
ATOM   3027 C C   . ILE A  1 591 ? 182.918 214.762 173.861 1.00 73.77  ? 591 ILE B C   1 
ATOM   3028 O O   . ILE A  1 591 ? 183.331 214.133 174.843 1.00 69.57  ? 591 ILE B O   1 
ATOM   3029 C CB  . ILE A  1 591 ? 183.860 214.364 171.550 1.00 72.16  ? 591 ILE B CB  1 
ATOM   3030 C CG1 . ILE A  1 591 ? 183.650 213.639 170.222 1.00 74.55  ? 591 ILE B CG1 1 
ATOM   3031 C CG2 . ILE A  1 591 ? 185.188 213.963 172.167 1.00 67.96  ? 591 ILE B CG2 1 
ATOM   3032 C CD1 . ILE A  1 591 ? 183.598 214.556 169.026 1.00 72.69  ? 591 ILE B CD1 1 
ATOM   3033 N N   . ILE A  1 592 ? 182.637 216.065 173.922 1.00 76.11  ? 592 ILE B N   1 
ATOM   3034 C CA  . ILE A  1 592 ? 182.850 216.812 175.160 1.00 75.13  ? 592 ILE B CA  1 
ATOM   3035 C C   . ILE A  1 592 ? 181.959 216.269 176.270 1.00 74.15  ? 592 ILE B C   1 
ATOM   3036 O O   . ILE A  1 592 ? 182.411 216.042 177.399 1.00 77.41  ? 592 ILE B O   1 
ATOM   3037 C CB  . ILE A  1 592 ? 182.615 218.316 174.931 1.00 74.01  ? 592 ILE B CB  1 
ATOM   3038 C CG1 . ILE A  1 592 ? 183.535 218.841 173.828 1.00 74.30  ? 592 ILE B CG1 1 
ATOM   3039 C CG2 . ILE A  1 592 ? 182.841 219.090 176.218 1.00 74.74  ? 592 ILE B CG2 1 
ATOM   3040 C CD1 . ILE A  1 592 ? 185.002 218.574 174.077 1.00 73.98  ? 592 ILE B CD1 1 
ATOM   3041 N N   . ALA A  1 593 ? 180.679 216.045 175.964 1.00 67.36  ? 593 ALA B N   1 
ATOM   3042 C CA  . ALA A  1 593 ? 179.756 215.540 176.974 1.00 68.85  ? 593 ALA B CA  1 
ATOM   3043 C C   . ALA A  1 593 ? 180.162 214.152 177.452 1.00 70.08  ? 593 ALA B C   1 
ATOM   3044 O O   . ALA A  1 593 ? 180.178 213.883 178.660 1.00 74.84  ? 593 ALA B O   1 
ATOM   3045 C CB  . ALA A  1 593 ? 178.332 215.523 176.422 1.00 65.33  ? 593 ALA B CB  1 
ATOM   3046 N N   . THR A  1 594 ? 180.511 213.261 176.520 1.00 59.06  ? 594 THR B N   1 
ATOM   3047 C CA  . THR A  1 594 ? 180.875 211.900 176.895 1.00 55.68  ? 594 THR B CA  1 
ATOM   3048 C C   . THR A  1 594 ? 182.163 211.873 177.702 1.00 63.68  ? 594 THR B C   1 
ATOM   3049 O O   . THR A  1 594 ? 182.316 211.042 178.605 1.00 69.30  ? 594 THR B O   1 
ATOM   3050 C CB  . THR A  1 594 ? 181.014 211.030 175.648 1.00 60.17  ? 594 THR B CB  1 
ATOM   3051 O OG1 . THR A  1 594 ? 180.000 211.383 174.700 1.00 63.64  ? 594 THR B OG1 1 
ATOM   3052 C CG2 . THR A  1 594 ? 180.873 209.564 176.011 1.00 65.09  ? 594 THR B CG2 1 
ATOM   3053 N N   . VAL A  1 595 ? 183.104 212.767 177.395 1.00 63.16  ? 595 VAL B N   1 
ATOM   3054 C CA  . VAL A  1 595 ? 184.372 212.752 178.110 1.00 63.03  ? 595 VAL B CA  1 
ATOM   3055 C C   . VAL A  1 595 ? 184.290 213.491 179.438 1.00 62.50  ? 595 VAL B C   1 
ATOM   3056 O O   . VAL A  1 595 ? 185.122 213.246 180.316 1.00 59.26  ? 595 VAL B O   1 
ATOM   3057 C CB  . VAL A  1 595 ? 185.497 213.343 177.241 1.00 60.86  ? 595 VAL B CB  1 
ATOM   3058 C CG1 . VAL A  1 595 ? 185.412 214.859 177.198 1.00 61.75  ? 595 VAL B CG1 1 
ATOM   3059 C CG2 . VAL A  1 595 ? 186.860 212.888 177.741 1.00 61.56  ? 595 VAL B CG2 1 
ATOM   3060 N N   . PHE A  1 596 ? 183.304 214.372 179.626 1.00 66.02  ? 596 PHE B N   1 
ATOM   3061 C CA  . PHE A  1 596 ? 183.241 215.164 180.847 1.00 64.12  ? 596 PHE B CA  1 
ATOM   3062 C C   . PHE A  1 596 ? 182.185 214.700 181.844 1.00 63.26  ? 596 PHE B C   1 
ATOM   3063 O O   . PHE A  1 596 ? 182.277 215.068 183.020 1.00 67.34  ? 596 PHE B O   1 
ATOM   3064 C CB  . PHE A  1 596 ? 182.991 216.638 180.512 1.00 60.26  ? 596 PHE B CB  1 
ATOM   3065 C CG  . PHE A  1 596 ? 184.237 217.473 180.461 1.00 67.33  ? 596 PHE B CG  1 
ATOM   3066 C CD1 . PHE A  1 596 ? 185.053 217.593 181.573 1.00 67.68  ? 596 PHE B CD1 1 
ATOM   3067 C CD2 . PHE A  1 596 ? 184.582 218.155 179.307 1.00 69.22  ? 596 PHE B CD2 1 
ATOM   3068 C CE1 . PHE A  1 596 ? 186.199 218.364 181.531 1.00 65.28  ? 596 PHE B CE1 1 
ATOM   3069 C CE2 . PHE A  1 596 ? 185.726 218.928 179.259 1.00 70.78  ? 596 PHE B CE2 1 
ATOM   3070 C CZ  . PHE A  1 596 ? 186.535 219.033 180.373 1.00 68.71  ? 596 PHE B CZ  1 
ATOM   3071 N N   . ALA A  1 597 ? 181.184 213.927 181.420 1.00 54.31  ? 597 ALA B N   1 
ATOM   3072 C CA  . ALA A  1 597 ? 180.231 213.379 182.384 1.00 53.66  ? 597 ALA B CA  1 
ATOM   3073 C C   . ALA A  1 597 ? 180.893 212.507 183.451 1.00 59.01  ? 597 ALA B C   1 
ATOM   3074 O O   . ALA A  1 597 ? 180.499 212.614 184.630 1.00 63.21  ? 597 ALA B O   1 
ATOM   3075 C CB  . ALA A  1 597 ? 179.128 212.612 181.644 1.00 51.85  ? 597 ALA B CB  1 
ATOM   3076 N N   . PRO A  1 598 ? 181.857 211.635 183.133 1.00 45.77  ? 598 PRO B N   1 
ATOM   3077 C CA  . PRO A  1 598 ? 182.598 210.970 184.213 1.00 41.09  ? 598 PRO B CA  1 
ATOM   3078 C C   . PRO A  1 598 ? 183.251 211.944 185.174 1.00 49.07  ? 598 PRO B C   1 
ATOM   3079 O O   . PRO A  1 598 ? 183.324 211.653 186.372 1.00 56.06  ? 598 PRO B O   1 
ATOM   3080 C CB  . PRO A  1 598 ? 183.636 210.133 183.456 1.00 51.40  ? 598 PRO B CB  1 
ATOM   3081 C CG  . PRO A  1 598 ? 182.985 209.837 182.167 1.00 52.02  ? 598 PRO B CG  1 
ATOM   3082 C CD  . PRO A  1 598 ? 182.204 211.067 181.818 1.00 45.93  ? 598 PRO B CD  1 
ATOM   3083 N N   . LEU A  1 599 ? 183.719 213.101 184.699 1.00 49.86  ? 599 LEU B N   1 
ATOM   3084 C CA  . LEU A  1 599 ? 184.213 214.104 185.636 1.00 50.64  ? 599 LEU B CA  1 
ATOM   3085 C C   . LEU A  1 599 ? 183.090 214.718 186.461 1.00 53.49  ? 599 LEU B C   1 
ATOM   3086 O O   . LEU A  1 599 ? 183.333 215.148 187.590 1.00 57.27  ? 599 LEU B O   1 
ATOM   3087 C CB  . LEU A  1 599 ? 185.009 215.193 184.915 1.00 48.00  ? 599 LEU B CB  1 
ATOM   3088 C CG  . LEU A  1 599 ? 186.357 214.791 184.311 1.00 52.38  ? 599 LEU B CG  1 
ATOM   3089 C CD1 . LEU A  1 599 ? 187.050 213.752 185.182 1.00 48.19  ? 599 LEU B CD1 1 
ATOM   3090 C CD2 . LEU A  1 599 ? 186.219 214.296 182.900 1.00 53.97  ? 599 LEU B CD2 1 
ATOM   3091 N N   . GLU A  1 600 ? 181.860 214.677 185.982 1.00 53.88  ? 600 GLU B N   1 
ATOM   3092 C CA  . GLU A  1 600 ? 180.748 215.157 186.796 1.00 46.37  ? 600 GLU B CA  1 
ATOM   3093 C C   . GLU A  1 600 ? 180.470 214.152 187.908 1.00 58.52  ? 600 GLU B C   1 
ATOM   3094 O O   . GLU A  1 600 ? 180.163 214.555 189.024 1.00 58.72  ? 600 GLU B O   1 
ATOM   3095 C CB  . GLU A  1 600 ? 179.524 215.378 185.925 1.00 47.64  ? 600 GLU B CB  1 
ATOM   3096 C CG  . GLU A  1 600 ? 178.321 216.010 186.589 1.00 53.56  ? 600 GLU B CG  1 
ATOM   3097 C CD  . GLU A  1 600 ? 177.173 216.132 185.610 1.00 63.64  ? 600 GLU B CD  1 
ATOM   3098 O OE1 . GLU A  1 600 ? 176.044 216.463 186.026 1.00 57.25  ? 600 GLU B OE1 1 
ATOM   3099 O OE2 . GLU A  1 600 ? 177.407 215.877 184.412 1.00 68.96  ? 600 GLU B OE2 1 
ATOM   3100 N N   . VAL A  1 601 ? 180.588 212.849 187.633 1.00 52.40  ? 601 VAL B N   1 
ATOM   3101 C CA  . VAL A  1 601 ? 180.427 211.873 188.705 1.00 35.05  ? 601 VAL B CA  1 
ATOM   3102 C C   . VAL A  1 601 ? 181.617 211.918 189.655 1.00 42.40  ? 601 VAL B C   1 
ATOM   3103 O O   . VAL A  1 601 ? 181.460 211.715 190.861 1.00 45.65  ? 601 VAL B O   1 
ATOM   3104 C CB  . VAL A  1 601 ? 180.204 210.467 188.127 1.00 30.01  ? 601 VAL B CB  1 
ATOM   3105 C CG1 . VAL A  1 601 ? 179.890 209.498 189.239 1.00 40.87  ? 601 VAL B CG1 1 
ATOM   3106 C CG2 . VAL A  1 601 ? 179.065 210.499 187.135 1.00 34.06  ? 601 VAL B CG2 1 
ATOM   3107 N N   . PHE A  1 602 ? 182.815 212.209 189.144 1.00 35.42  ? 602 PHE B N   1 
ATOM   3108 C CA  . PHE A  1 602 ? 183.983 212.344 190.011 1.00 28.47  ? 602 PHE B CA  1 
ATOM   3109 C C   . PHE A  1 602 ? 183.868 213.563 190.922 1.00 43.53  ? 602 PHE B C   1 
ATOM   3110 O O   . PHE A  1 602 ? 184.235 213.502 192.102 1.00 58.52  ? 602 PHE B O   1 
ATOM   3111 C CB  . PHE A  1 602 ? 185.252 212.422 189.166 1.00 26.12  ? 602 PHE B CB  1 
ATOM   3112 C CG  . PHE A  1 602 ? 186.500 212.637 189.967 1.00 40.65  ? 602 PHE B CG  1 
ATOM   3113 C CD1 . PHE A  1 602 ? 187.100 211.584 190.632 1.00 50.26  ? 602 PHE B CD1 1 
ATOM   3114 C CD2 . PHE A  1 602 ? 187.077 213.890 190.051 1.00 40.74  ? 602 PHE B CD2 1 
ATOM   3115 C CE1 . PHE A  1 602 ? 188.247 211.779 191.370 1.00 47.96  ? 602 PHE B CE1 1 
ATOM   3116 C CE2 . PHE A  1 602 ? 188.224 214.090 190.787 1.00 38.72  ? 602 PHE B CE2 1 
ATOM   3117 C CZ  . PHE A  1 602 ? 188.810 213.033 191.446 1.00 40.60  ? 602 PHE B CZ  1 
ATOM   3118 N N   . ARG A  1 603 ? 183.379 214.684 190.388 1.00 37.17  ? 603 ARG B N   1 
ATOM   3119 C CA  . ARG A  1 603 ? 183.181 215.871 191.210 1.00 36.58  ? 603 ARG B CA  1 
ATOM   3120 C C   . ARG A  1 603 ? 182.139 215.616 192.283 1.00 36.59  ? 603 ARG B C   1 
ATOM   3121 O O   . ARG A  1 603 ? 182.287 216.063 193.424 1.00 43.02  ? 603 ARG B O   1 
ATOM   3122 C CB  . ARG A  1 603 ? 182.769 217.057 190.342 1.00 39.76  ? 603 ARG B CB  1 
ATOM   3123 C CG  . ARG A  1 603 ? 182.786 218.384 191.078 1.00 33.52  ? 603 ARG B CG  1 
ATOM   3124 C CD  . ARG A  1 603 ? 181.664 219.297 190.619 1.00 41.71  ? 603 ARG B CD  1 
ATOM   3125 N NE  . ARG A  1 603 ? 180.419 219.037 191.329 1.00 38.69  ? 603 ARG B NE  1 
ATOM   3126 C CZ  . ARG A  1 603 ? 179.264 218.767 190.739 1.00 45.15  ? 603 ARG B CZ  1 
ATOM   3127 N NH1 . ARG A  1 603 ? 179.157 218.708 189.422 1.00 40.24  ? 603 ARG B NH1 1 
ATOM   3128 N NH2 . ARG A  1 603 ? 178.188 218.551 191.489 1.00 49.16  ? 603 ARG B NH2 1 
ATOM   3129 N N   . ARG A  1 604 ? 181.072 214.899 191.936 1.00 34.40  ? 604 ARG B N   1 
ATOM   3130 C CA  . ARG A  1 604 ? 180.087 214.533 192.946 1.00 28.83  ? 604 ARG B CA  1 
ATOM   3131 C C   . ARG A  1 604 ? 180.690 213.593 193.982 1.00 37.00  ? 604 ARG B C   1 
ATOM   3132 O O   . ARG A  1 604 ? 180.381 213.688 195.174 1.00 43.00  ? 604 ARG B O   1 
ATOM   3133 C CB  . ARG A  1 604 ? 178.874 213.897 192.279 1.00 27.04  ? 604 ARG B CB  1 
ATOM   3134 C CG  . ARG A  1 604 ? 177.759 213.588 193.236 1.00 23.54  ? 604 ARG B CG  1 
ATOM   3135 C CD  . ARG A  1 604 ? 177.387 214.796 194.073 1.00 21.88  ? 604 ARG B CD  1 
ATOM   3136 N NE  . ARG A  1 604 ? 176.765 215.840 193.270 1.00 30.87  ? 604 ARG B NE  1 
ATOM   3137 C CZ  . ARG A  1 604 ? 176.131 216.891 193.766 1.00 32.17  ? 604 ARG B CZ  1 
ATOM   3138 N NH1 . ARG A  1 604 ? 176.001 217.068 195.070 1.00 26.69  ? 604 ARG B NH1 1 
ATOM   3139 N NH2 . ARG A  1 604 ? 175.612 217.788 192.934 1.00 34.92  ? 604 ARG B NH2 1 
ATOM   3140 N N   . PHE A  1 605 ? 181.560 212.683 193.541 1.00 30.66  ? 605 PHE B N   1 
ATOM   3141 C CA  . PHE A  1 605 ? 182.220 211.753 194.451 1.00 22.42  ? 605 PHE B CA  1 
ATOM   3142 C C   . PHE A  1 605 ? 183.079 212.493 195.467 1.00 32.79  ? 605 PHE B C   1 
ATOM   3143 O O   . PHE A  1 605 ? 183.053 212.181 196.663 1.00 44.25  ? 605 PHE B O   1 
ATOM   3144 C CB  . PHE A  1 605 ? 183.051 210.761 193.634 1.00 29.39  ? 605 PHE B CB  1 
ATOM   3145 C CG  . PHE A  1 605 ? 184.327 210.321 194.298 1.00 38.87  ? 605 PHE B CG  1 
ATOM   3146 C CD1 . PHE A  1 605 ? 184.306 209.488 195.399 1.00 40.26  ? 605 PHE B CD1 1 
ATOM   3147 C CD2 . PHE A  1 605 ? 185.551 210.728 193.800 1.00 35.01  ? 605 PHE B CD2 1 
ATOM   3148 C CE1 . PHE A  1 605 ? 185.479 209.081 195.995 1.00 31.41  ? 605 PHE B CE1 1 
ATOM   3149 C CE2 . PHE A  1 605 ? 186.725 210.324 194.395 1.00 27.90  ? 605 PHE B CE2 1 
ATOM   3150 C CZ  . PHE A  1 605 ? 186.688 209.500 195.494 1.00 28.66  ? 605 PHE B CZ  1 
ATOM   3151 N N   . VAL A  1 606 ? 183.850 213.480 195.009 1.00 32.98  ? 606 VAL B N   1 
ATOM   3152 C CA  . VAL A  1 606 ? 184.679 214.237 195.945 1.00 33.78  ? 606 VAL B CA  1 
ATOM   3153 C C   . VAL A  1 606 ? 183.823 215.167 196.804 1.00 44.02  ? 606 VAL B C   1 
ATOM   3154 O O   . VAL A  1 606 ? 184.124 215.378 197.984 1.00 51.47  ? 606 VAL B O   1 
ATOM   3155 C CB  . VAL A  1 606 ? 185.794 215.000 195.205 1.00 29.53  ? 606 VAL B CB  1 
ATOM   3156 C CG1 . VAL A  1 606 ? 185.218 215.998 194.244 1.00 40.20  ? 606 VAL B CG1 1 
ATOM   3157 C CG2 . VAL A  1 606 ? 186.706 215.695 196.196 1.00 31.74  ? 606 VAL B CG2 1 
ATOM   3158 N N   . TRP A  1 607 ? 182.746 215.727 196.243 1.00 41.39  ? 607 TRP B N   1 
ATOM   3159 C CA  . TRP A  1 607 ? 181.844 216.563 197.029 1.00 23.00  ? 607 TRP B CA  1 
ATOM   3160 C C   . TRP A  1 607 ? 181.180 215.768 198.141 1.00 24.85  ? 607 TRP B C   1 
ATOM   3161 O O   . TRP A  1 607 ? 180.891 216.318 199.210 1.00 37.31  ? 607 TRP B O   1 
ATOM   3162 C CB  . TRP A  1 607 ? 180.787 217.185 196.114 1.00 31.82  ? 607 TRP B CB  1 
ATOM   3163 C CG  . TRP A  1 607 ? 179.654 217.874 196.824 1.00 31.88  ? 607 TRP B CG  1 
ATOM   3164 C CD1 . TRP A  1 607 ? 179.552 219.205 197.094 1.00 33.22  ? 607 TRP B CD1 1 
ATOM   3165 C CD2 . TRP A  1 607 ? 178.452 217.272 197.325 1.00 26.56  ? 607 TRP B CD2 1 
ATOM   3166 N NE1 . TRP A  1 607 ? 178.372 219.468 197.743 1.00 27.94  ? 607 TRP B NE1 1 
ATOM   3167 C CE2 . TRP A  1 607 ? 177.679 218.297 197.897 1.00 20.98  ? 607 TRP B CE2 1 
ATOM   3168 C CE3 . TRP A  1 607 ? 177.961 215.965 197.352 1.00 37.68  ? 607 TRP B CE3 1 
ATOM   3169 C CZ2 . TRP A  1 607 ? 176.443 218.057 198.487 1.00 24.16  ? 607 TRP B CZ2 1 
ATOM   3170 C CZ3 . TRP A  1 607 ? 176.733 215.730 197.938 1.00 29.60  ? 607 TRP B CZ3 1 
ATOM   3171 C CH2 . TRP A  1 607 ? 175.990 216.770 198.497 1.00 27.60  ? 607 TRP B CH2 1 
ATOM   3172 N N   . ASN A  1 608 ? 180.916 214.483 197.898 1.00 24.42  ? 608 ASN B N   1 
ATOM   3173 C CA  . ASN A  1 608 ? 180.299 213.639 198.913 1.00 20.00  ? 608 ASN B CA  1 
ATOM   3174 C C   . ASN A  1 608 ? 181.167 213.560 200.156 1.00 31.55  ? 608 ASN B C   1 
ATOM   3175 O O   . ASN A  1 608 ? 180.664 213.660 201.283 1.00 39.99  ? 608 ASN B O   1 
ATOM   3176 C CB  . ASN A  1 608 ? 180.062 212.241 198.349 1.00 13.15  ? 608 ASN B CB  1 
ATOM   3177 C CG  . ASN A  1 608 ? 178.625 212.007 197.960 1.00 33.03  ? 608 ASN B CG  1 
ATOM   3178 O OD1 . ASN A  1 608 ? 177.705 212.359 198.695 1.00 37.88  ? 608 ASN B OD1 1 
ATOM   3179 N ND2 . ASN A  1 608 ? 178.422 211.406 196.795 1.00 43.41  ? 608 ASN B ND2 1 
ATOM   3180 N N   . PHE A  1 609 ? 182.479 213.399 199.966 1.00 31.04  ? 609 PHE B N   1 
ATOM   3181 C CA  . PHE A  1 609 ? 183.399 213.276 201.090 1.00 31.85  ? 609 PHE B CA  1 
ATOM   3182 C C   . PHE A  1 609 ? 183.254 214.452 202.041 1.00 42.38  ? 609 PHE B C   1 
ATOM   3183 O O   . PHE A  1 609 ? 182.992 214.279 203.237 1.00 55.81  ? 609 PHE B O   1 
ATOM   3184 C CB  . PHE A  1 609 ? 184.838 213.204 200.577 1.00 17.78  ? 609 PHE B CB  1 
ATOM   3185 C CG  . PHE A  1 609 ? 185.330 211.815 200.333 1.00 25.52  ? 609 PHE B CG  1 
ATOM   3186 C CD1 . PHE A  1 609 ? 185.140 210.824 201.272 1.00 35.57  ? 609 PHE B CD1 1 
ATOM   3187 C CD2 . PHE A  1 609 ? 186.005 211.508 199.170 1.00 28.57  ? 609 PHE B CD2 1 
ATOM   3188 C CE1 . PHE A  1 609 ? 185.597 209.548 201.049 1.00 41.40  ? 609 PHE B CE1 1 
ATOM   3189 C CE2 . PHE A  1 609 ? 186.467 210.236 198.943 1.00 27.73  ? 609 PHE B CE2 1 
ATOM   3190 C CZ  . PHE A  1 609 ? 186.262 209.253 199.883 1.00 31.36  ? 609 PHE B CZ  1 
ATOM   3191 N N   . PHE A  1 610 ? 183.362 215.664 201.507 1.00 32.46  ? 610 PHE B N   1 
ATOM   3192 C CA  . PHE A  1 610 ? 183.410 216.834 202.368 1.00 35.01  ? 610 PHE B CA  1 
ATOM   3193 C C   . PHE A  1 610 ? 182.030 217.280 202.820 1.00 36.23  ? 610 PHE B C   1 
ATOM   3194 O O   . PHE A  1 610 ? 181.905 217.826 203.918 1.00 48.79  ? 610 PHE B O   1 
ATOM   3195 C CB  . PHE A  1 610 ? 184.162 217.956 201.660 1.00 27.62  ? 610 PHE B CB  1 
ATOM   3196 C CG  . PHE A  1 610 ? 185.549 217.566 201.259 1.00 26.10  ? 610 PHE B CG  1 
ATOM   3197 C CD1 . PHE A  1 610 ? 186.551 217.477 202.205 1.00 25.21  ? 610 PHE B CD1 1 
ATOM   3198 C CD2 . PHE A  1 610 ? 185.843 217.247 199.948 1.00 42.39  ? 610 PHE B CD2 1 
ATOM   3199 C CE1 . PHE A  1 610 ? 187.825 217.103 201.847 1.00 36.16  ? 610 PHE B CE1 1 
ATOM   3200 C CE2 . PHE A  1 610 ? 187.115 216.869 199.586 1.00 35.04  ? 610 PHE B CE2 1 
ATOM   3201 C CZ  . PHE A  1 610 ? 188.107 216.799 200.535 1.00 36.85  ? 610 PHE B CZ  1 
ATOM   3202 N N   . ARG A  1 611 ? 180.977 217.024 202.040 1.00 23.54  ? 611 ARG B N   1 
ATOM   3203 C CA  . ARG A  1 611 ? 179.640 217.299 202.551 1.00 9.74   ? 611 ARG B CA  1 
ATOM   3204 C C   . ARG A  1 611 ? 179.321 216.397 203.736 1.00 25.75  ? 611 ARG B C   1 
ATOM   3205 O O   . ARG A  1 611 ? 178.827 216.868 204.766 1.00 50.61  ? 611 ARG B O   1 
ATOM   3206 C CB  . ARG A  1 611 ? 178.599 217.143 201.442 1.00 29.86  ? 611 ARG B CB  1 
ATOM   3207 C CG  . ARG A  1 611 ? 177.220 216.703 201.916 1.00 33.30  ? 611 ARG B CG  1 
ATOM   3208 C CD  . ARG A  1 611 ? 176.535 217.752 202.790 1.00 27.05  ? 611 ARG B CD  1 
ATOM   3209 N NE  . ARG A  1 611 ? 175.936 218.841 202.031 1.00 28.46  ? 611 ARG B NE  1 
ATOM   3210 C CZ  . ARG A  1 611 ? 175.128 219.751 202.555 1.00 37.89  ? 611 ARG B CZ  1 
ATOM   3211 N NH1 . ARG A  1 611 ? 174.807 219.733 203.838 1.00 41.24  ? 611 ARG B NH1 1 
ATOM   3212 N NH2 . ARG A  1 611 ? 174.627 220.703 201.773 1.00 42.68  ? 611 ARG B NH2 1 
ATOM   3213 N N   . LEU A  1 612 ? 179.619 215.099 203.626 1.00 27.01  ? 612 LEU B N   1 
ATOM   3214 C CA  . LEU A  1 612 ? 179.357 214.204 204.748 1.00 33.14  ? 612 LEU B CA  1 
ATOM   3215 C C   . LEU A  1 612 ? 180.250 214.534 205.937 1.00 48.22  ? 612 LEU B C   1 
ATOM   3216 O O   . LEU A  1 612 ? 179.812 214.456 207.092 1.00 46.86  ? 612 LEU B O   1 
ATOM   3217 C CB  . LEU A  1 612 ? 179.543 212.751 204.318 1.00 26.98  ? 612 LEU B CB  1 
ATOM   3218 C CG  . LEU A  1 612 ? 178.256 211.988 204.009 1.00 27.67  ? 612 LEU B CG  1 
ATOM   3219 C CD1 . LEU A  1 612 ? 177.373 211.915 205.237 1.00 32.18  ? 612 LEU B CD1 1 
ATOM   3220 C CD2 . LEU A  1 612 ? 177.517 212.634 202.854 1.00 33.59  ? 612 LEU B CD2 1 
ATOM   3221 N N   . GLU A  1 613 ? 181.505 214.911 205.678 1.00 48.88  ? 613 GLU B N   1 
ATOM   3222 C CA  . GLU A  1 613 ? 182.398 215.295 206.765 1.00 43.55  ? 613 GLU B CA  1 
ATOM   3223 C C   . GLU A  1 613 ? 181.902 216.549 207.477 1.00 44.48  ? 613 GLU B C   1 
ATOM   3224 O O   . GLU A  1 613 ? 181.946 216.626 208.710 1.00 54.49  ? 613 GLU B O   1 
ATOM   3225 C CB  . GLU A  1 613 ? 183.811 215.486 206.218 1.00 40.54  ? 613 GLU B CB  1 
ATOM   3226 C CG  . GLU A  1 613 ? 184.806 216.051 207.200 1.00 51.92  ? 613 GLU B CG  1 
ATOM   3227 C CD  . GLU A  1 613 ? 185.603 217.192 206.613 1.00 53.45  ? 613 GLU B CD  1 
ATOM   3228 O OE1 . GLU A  1 613 ? 185.261 217.650 205.503 1.00 54.81  ? 613 GLU B OE1 1 
ATOM   3229 O OE2 . GLU A  1 613 ? 186.576 217.633 207.257 1.00 59.89  ? 613 GLU B OE2 1 
ATOM   3230 N N   . ASN A  1 614 ? 181.415 217.535 206.720 1.00 40.28  ? 614 ASN B N   1 
ATOM   3231 C CA  . ASN A  1 614 ? 180.826 218.722 207.329 1.00 43.54  ? 614 ASN B CA  1 
ATOM   3232 C C   . ASN A  1 614 ? 179.588 218.365 208.136 1.00 37.52  ? 614 ASN B C   1 
ATOM   3233 O O   . ASN A  1 614 ? 179.375 218.899 209.229 1.00 53.55  ? 614 ASN B O   1 
ATOM   3234 C CB  . ASN A  1 614 ? 180.485 219.746 206.249 1.00 41.00  ? 614 ASN B CB  1 
ATOM   3235 C CG  . ASN A  1 614 ? 180.446 221.161 206.779 1.00 35.57  ? 614 ASN B CG  1 
ATOM   3236 O OD1 . ASN A  1 614 ? 179.828 222.042 206.186 1.00 31.35  ? 614 ASN B OD1 1 
ATOM   3237 N ND2 . ASN A  1 614 ? 181.113 221.388 207.903 1.00 45.60  ? 614 ASN B ND2 1 
ATOM   3238 N N   . GLU A  1 615 ? 178.759 217.460 207.610 1.00 26.17  ? 615 GLU B N   1 
ATOM   3239 C CA  . GLU A  1 615 ? 177.570 217.032 208.338 1.00 32.53  ? 615 GLU B CA  1 
ATOM   3240 C C   . GLU A  1 615 ? 177.944 216.397 209.670 1.00 51.44  ? 615 GLU B C   1 
ATOM   3241 O O   . GLU A  1 615 ? 177.301 216.655 210.694 1.00 59.51  ? 615 GLU B O   1 
ATOM   3242 C CB  . GLU A  1 615 ? 176.768 216.046 207.493 1.00 35.55  ? 615 GLU B CB  1 
ATOM   3243 C CG  . GLU A  1 615 ? 176.058 216.665 206.314 1.00 44.97  ? 615 GLU B CG  1 
ATOM   3244 C CD  . GLU A  1 615 ? 174.839 217.455 206.718 1.00 52.48  ? 615 GLU B CD  1 
ATOM   3245 O OE1 . GLU A  1 615 ? 173.878 216.847 207.232 1.00 52.44  ? 615 GLU B OE1 1 
ATOM   3246 O OE2 . GLU A  1 615 ? 174.838 218.683 206.510 1.00 49.00  ? 615 GLU B OE2 1 
ATOM   3247 N N   . HIS A  1 616 ? 178.976 215.553 209.671 1.00 47.51  ? 616 HIS B N   1 
ATOM   3248 C CA  . HIS A  1 616 ? 179.423 214.938 210.916 1.00 45.49  ? 616 HIS B CA  1 
ATOM   3249 C C   . HIS A  1 616 ? 179.983 215.976 211.879 1.00 49.40  ? 616 HIS B C   1 
ATOM   3250 O O   . HIS A  1 616 ? 179.674 215.953 213.076 1.00 53.26  ? 616 HIS B O   1 
ATOM   3251 C CB  . HIS A  1 616 ? 180.472 213.870 210.627 1.00 48.89  ? 616 HIS B CB  1 
ATOM   3252 C CG  . HIS A  1 616 ? 181.137 213.327 211.852 1.00 53.58  ? 616 HIS B CG  1 
ATOM   3253 N ND1 . HIS A  1 616 ? 180.476 212.541 212.771 1.00 54.39  ? 616 HIS B ND1 1 
ATOM   3254 C CD2 . HIS A  1 616 ? 182.405 213.455 212.309 1.00 54.23  ? 616 HIS B CD2 1 
ATOM   3255 C CE1 . HIS A  1 616 ? 181.308 212.209 213.742 1.00 49.30  ? 616 HIS B CE1 1 
ATOM   3256 N NE2 . HIS A  1 616 ? 182.485 212.750 213.485 1.00 52.44  ? 616 HIS B NE2 1 
ATOM   3257 N N   . LEU A  1 617 ? 180.808 216.896 211.377 1.00 47.06  ? 617 LEU B N   1 
ATOM   3258 C CA  . LEU A  1 617 ? 181.492 217.835 212.260 1.00 46.68  ? 617 LEU B CA  1 
ATOM   3259 C C   . LEU A  1 617 ? 180.522 218.857 212.840 1.00 58.72  ? 617 LEU B C   1 
ATOM   3260 O O   . LEU A  1 617 ? 180.307 218.905 214.057 1.00 68.44  ? 617 LEU B O   1 
ATOM   3261 C CB  . LEU A  1 617 ? 182.624 218.530 211.504 1.00 48.47  ? 617 LEU B CB  1 
ATOM   3262 C CG  . LEU A  1 617 ? 183.822 217.653 211.143 1.00 56.41  ? 617 LEU B CG  1 
ATOM   3263 C CD1 . LEU A  1 617 ? 185.056 218.506 210.938 1.00 54.14  ? 617 LEU B CD1 1 
ATOM   3264 C CD2 . LEU A  1 617 ? 184.068 216.607 212.216 1.00 57.73  ? 617 LEU B CD2 1 
ATOM   3265 N N   . ASN A  1 618 ? 179.919 219.679 211.986 1.00 49.25  ? 618 ASN B N   1 
ATOM   3266 C CA  . ASN A  1 618 ? 178.994 220.716 212.424 1.00 44.78  ? 618 ASN B CA  1 
ATOM   3267 C C   . ASN A  1 618 ? 177.751 220.645 211.555 1.00 46.28  ? 618 ASN B C   1 
ATOM   3268 O O   . ASN A  1 618 ? 177.834 220.842 210.339 1.00 55.22  ? 618 ASN B O   1 
ATOM   3269 C CB  . ASN A  1 618 ? 179.638 222.103 212.347 1.00 47.15  ? 618 ASN B CB  1 
ATOM   3270 C CG  . ASN A  1 618 ? 180.416 222.313 211.067 1.00 47.33  ? 618 ASN B CG  1 
ATOM   3271 O OD1 . ASN A  1 618 ? 179.981 223.042 210.178 1.00 51.59  ? 618 ASN B OD1 1 
ATOM   3272 N ND2 . ASN A  1 618 ? 181.576 221.675 210.967 1.00 42.23  ? 618 ASN B ND2 1 
ATOM   3273 N N   . ASN A  1 619 ? 176.610 220.367 212.180 1.00 50.48  ? 619 ASN B N   1 
ATOM   3274 C CA  . ASN A  1 619 ? 175.360 220.126 211.470 1.00 45.56  ? 619 ASN B CA  1 
ATOM   3275 C C   . ASN A  1 619 ? 175.060 221.227 210.461 1.00 57.88  ? 619 ASN B C   1 
ATOM   3276 O O   . ASN A  1 619 ? 174.953 222.403 210.821 1.00 66.40  ? 619 ASN B O   1 
ATOM   3277 C CB  . ASN A  1 619 ? 174.221 220.010 212.485 1.00 48.94  ? 619 ASN B CB  1 
ATOM   3278 C CG  . ASN A  1 619 ? 172.913 219.586 211.853 1.00 60.51  ? 619 ASN B CG  1 
ATOM   3279 O OD1 . ASN A  1 619 ? 172.853 219.278 210.664 1.00 68.71  ? 619 ASN B OD1 1 
ATOM   3280 N ND2 . ASN A  1 619 ? 171.853 219.569 212.651 1.00 64.13  ? 619 ASN B ND2 1 
ATOM   3281 N N   . CYS A  1 620 ? 174.928 220.839 209.195 1.00 53.92  ? 620 CYS B N   1 
ATOM   3282 C CA  . CYS A  1 620 ? 174.502 221.734 208.131 1.00 53.68  ? 620 CYS B CA  1 
ATOM   3283 C C   . CYS A  1 620 ? 173.120 221.322 207.646 1.00 58.77  ? 620 CYS B C   1 
ATOM   3284 O O   . CYS A  1 620 ? 172.776 220.137 207.630 1.00 50.78  ? 620 CYS B O   1 
ATOM   3285 C CB  . CYS A  1 620 ? 175.482 221.725 206.955 1.00 44.76  ? 620 CYS B CB  1 
ATOM   3286 S SG  . CYS A  1 620 ? 177.195 221.418 207.397 1.00 65.17  ? 620 CYS B SG  1 
ATOM   3287 N N   . GLY A  1 621 ? 172.324 222.314 207.254 1.00 66.24  ? 621 GLY B N   1 
ATOM   3288 C CA  . GLY A  1 621 ? 170.944 222.080 206.892 1.00 61.58  ? 621 GLY B CA  1 
ATOM   3289 C C   . GLY A  1 621 ? 170.027 221.763 208.049 1.00 63.76  ? 621 GLY B C   1 
ATOM   3290 O O   . GLY A  1 621 ? 168.807 221.709 207.850 1.00 67.37  ? 621 GLY B O   1 
ATOM   3291 N N   . GLU A  1 622 ? 170.570 221.558 209.251 1.00 60.64  ? 622 GLU B N   1 
ATOM   3292 C CA  . GLU A  1 622 ? 169.782 221.287 210.451 1.00 65.01  ? 622 GLU B CA  1 
ATOM   3293 C C   . GLU A  1 622 ? 168.851 220.093 210.253 1.00 70.77  ? 622 GLU B C   1 
ATOM   3294 O O   . GLU A  1 622 ? 167.697 220.098 210.685 1.00 75.48  ? 622 GLU B O   1 
ATOM   3295 C CB  . GLU A  1 622 ? 169.004 222.530 210.887 1.00 69.07  ? 622 GLU B CB  1 
ATOM   3296 C CG  . GLU A  1 622 ? 169.891 223.678 211.350 1.00 69.81  ? 622 GLU B CG  1 
ATOM   3297 C CD  . GLU A  1 622 ? 170.015 224.785 210.322 1.00 75.29  ? 622 GLU B CD  1 
ATOM   3298 O OE1 . GLU A  1 622 ? 169.694 224.543 209.140 1.00 74.28  ? 622 GLU B OE1 1 
ATOM   3299 O OE2 . GLU A  1 622 ? 170.436 225.899 210.697 1.00 75.64  ? 622 GLU B OE2 1 
ATOM   3300 N N   . PHE A  1 623 ? 169.360 219.059 209.579 1.00 54.91  ? 623 PHE B N   1 
ATOM   3301 C CA  . PHE A  1 623 ? 168.613 217.811 209.474 1.00 54.49  ? 623 PHE B CA  1 
ATOM   3302 C C   . PHE A  1 623 ? 168.462 217.148 210.837 1.00 56.80  ? 623 PHE B C   1 
ATOM   3303 O O   . PHE A  1 623 ? 167.396 216.614 211.162 1.00 57.10  ? 623 PHE B O   1 
ATOM   3304 C CB  . PHE A  1 623 ? 169.305 216.860 208.499 1.00 50.15  ? 623 PHE B CB  1 
ATOM   3305 C CG  . PHE A  1 623 ? 169.238 217.302 207.068 1.00 46.57  ? 623 PHE B CG  1 
ATOM   3306 C CD1 . PHE A  1 623 ? 170.219 218.117 206.536 1.00 52.34  ? 623 PHE B CD1 1 
ATOM   3307 C CD2 . PHE A  1 623 ? 168.198 216.896 206.253 1.00 46.10  ? 623 PHE B CD2 1 
ATOM   3308 C CE1 . PHE A  1 623 ? 170.162 218.521 205.221 1.00 55.77  ? 623 PHE B CE1 1 
ATOM   3309 C CE2 . PHE A  1 623 ? 168.136 217.298 204.938 1.00 45.73  ? 623 PHE B CE2 1 
ATOM   3310 C CZ  . PHE A  1 623 ? 169.118 218.111 204.421 1.00 51.95  ? 623 PHE B CZ  1 
ATOM   3311 N N   . ARG A  1 624 ? 169.518 217.176 211.642 1.00 68.32  ? 624 ARG B N   1 
ATOM   3312 C CA  . ARG A  1 624 ? 169.539 216.517 212.937 1.00 72.65  ? 624 ARG B CA  1 
ATOM   3313 C C   . ARG A  1 624 ? 169.026 217.452 214.024 1.00 68.17  ? 624 ARG B C   1 
ATOM   3314 O O   . ARG A  1 624 ? 169.190 218.672 213.952 1.00 62.26  ? 624 ARG B O   1 
ATOM   3315 C CB  . ARG A  1 624 ? 170.958 216.057 213.272 1.00 72.70  ? 624 ARG B CB  1 
ATOM   3316 C CG  . ARG A  1 624 ? 171.043 214.934 214.285 1.00 67.83  ? 624 ARG B CG  1 
ATOM   3317 C CD  . ARG A  1 624 ? 172.273 214.067 214.045 1.00 69.76  ? 624 ARG B CD  1 
ATOM   3318 N NE  . ARG A  1 624 ? 173.503 214.847 213.970 1.00 72.29  ? 624 ARG B NE  1 
ATOM   3319 C CZ  . ARG A  1 624 ? 174.119 215.172 212.841 1.00 73.88  ? 624 ARG B CZ  1 
ATOM   3320 N NH1 . ARG A  1 624 ? 173.639 214.808 211.663 1.00 70.38  ? 624 ARG B NH1 1 
ATOM   3321 N NH2 . ARG A  1 624 ? 175.241 215.884 212.895 1.00 74.19  ? 624 ARG B NH2 1 
ATOM   3322 N N   . ALA A  1 625 ? 168.394 216.860 215.040 1.00 84.68  ? 625 ALA B N   1 
ATOM   3323 C CA  . ALA A  1 625 ? 167.903 217.649 216.164 1.00 89.41  ? 625 ALA B CA  1 
ATOM   3324 C C   . ALA A  1 625 ? 169.050 218.282 216.941 1.00 88.66  ? 625 ALA B C   1 
ATOM   3325 O O   . ALA A  1 625 ? 168.957 219.441 217.363 1.00 86.82  ? 625 ALA B O   1 
ATOM   3326 C CB  . ALA A  1 625 ? 167.048 216.778 217.083 1.00 87.56  ? 625 ALA B CB  1 
ATOM   3327 N N   . VAL A  1 626 ? 170.136 217.541 217.141 1.00 92.95  ? 626 VAL B N   1 
ATOM   3328 C CA  . VAL A  1 626 ? 171.282 218.041 217.891 1.00 96.28  ? 626 VAL B CA  1 
ATOM   3329 C C   . VAL A  1 626 ? 172.002 219.134 217.109 1.00 91.86  ? 626 VAL B C   1 
ATOM   3330 O O   . VAL A  1 626 ? 172.954 219.740 217.603 1.00 90.22  ? 626 VAL B O   1 
ATOM   3331 C CB  . VAL A  1 626 ? 172.254 216.902 218.246 1.00 94.92  ? 626 VAL B CB  1 
ATOM   3332 C CG1 . VAL A  1 626 ? 171.495 215.719 218.825 1.00 91.27  ? 626 VAL B CG1 1 
ATOM   3333 C CG2 . VAL A  1 626 ? 173.051 216.483 217.020 1.00 90.71  ? 626 VAL B CG2 1 
ATOM   3334 N N   . ALA B  1 226 ? 196.690 179.316 212.508 1.00 90.92  ? 226 ALA A N   1 
ATOM   3335 C CA  . ALA B  1 226 ? 195.598 179.391 211.545 1.00 93.30  ? 226 ALA A CA  1 
ATOM   3336 C C   . ALA B  1 226 ? 195.022 180.801 211.484 1.00 94.56  ? 226 ALA A C   1 
ATOM   3337 O O   . ALA B  1 226 ? 193.805 180.985 211.476 1.00 97.44  ? 226 ALA A O   1 
ATOM   3338 C CB  . ALA B  1 226 ? 194.510 178.388 211.898 1.00 92.10  ? 226 ALA A CB  1 
ATOM   3339 N N   . GLN B  1 227 ? 195.906 181.793 211.445 1.00 95.76  ? 227 GLN A N   1 
ATOM   3340 C CA  . GLN B  1 227 ? 195.464 183.177 211.366 1.00 95.78  ? 227 GLN A CA  1 
ATOM   3341 C C   . GLN B  1 227 ? 194.785 183.434 210.022 1.00 95.88  ? 227 GLN A C   1 
ATOM   3342 O O   . GLN B  1 227 ? 195.254 182.953 208.986 1.00 95.61  ? 227 GLN A O   1 
ATOM   3343 C CB  . GLN B  1 227 ? 196.646 184.128 211.546 1.00 95.58  ? 227 GLN A CB  1 
ATOM   3344 C CG  . GLN B  1 227 ? 197.355 183.991 212.884 1.00 96.71  ? 227 GLN A CG  1 
ATOM   3345 C CD  . GLN B  1 227 ? 198.500 184.972 213.041 1.00 96.39  ? 227 GLN A CD  1 
ATOM   3346 O OE1 . GLN B  1 227 ? 198.932 185.600 212.074 1.00 96.54  ? 227 GLN A OE1 1 
ATOM   3347 N NE2 . GLN B  1 227 ? 198.998 185.110 214.264 1.00 95.33  ? 227 GLN A NE2 1 
ATOM   3348 N N   . PRO B  1 228 ? 193.680 184.178 210.007 1.00 96.77  ? 228 PRO A N   1 
ATOM   3349 C CA  . PRO B  1 228 ? 192.989 184.441 208.741 1.00 94.47  ? 228 PRO A CA  1 
ATOM   3350 C C   . PRO B  1 228 ? 193.842 185.273 207.798 1.00 96.44  ? 228 PRO A C   1 
ATOM   3351 O O   . PRO B  1 228 ? 194.623 186.131 208.217 1.00 99.19  ? 228 PRO A O   1 
ATOM   3352 C CB  . PRO B  1 228 ? 191.733 185.205 209.174 1.00 92.13  ? 228 PRO A CB  1 
ATOM   3353 C CG  . PRO B  1 228 ? 192.105 185.829 210.475 1.00 95.40  ? 228 PRO A CG  1 
ATOM   3354 C CD  . PRO B  1 228 ? 193.035 184.857 211.144 1.00 96.49  ? 228 PRO A CD  1 
ATOM   3355 N N   . ALA B  1 229 ? 193.683 185.002 206.506 1.00 88.72  ? 229 ALA A N   1 
ATOM   3356 C CA  . ALA B  1 229 ? 194.416 185.741 205.495 1.00 85.50  ? 229 ALA A CA  1 
ATOM   3357 C C   . ALA B  1 229 ? 193.889 187.171 205.398 1.00 86.11  ? 229 ALA A C   1 
ATOM   3358 O O   . ALA B  1 229 ? 192.705 187.422 205.638 1.00 84.69  ? 229 ALA A O   1 
ATOM   3359 C CB  . ALA B  1 229 ? 194.302 185.048 204.141 1.00 83.84  ? 229 ALA A CB  1 
ATOM   3360 N N   . PRO B  1 230 ? 194.751 188.129 205.056 1.00 81.66  ? 230 PRO A N   1 
ATOM   3361 C CA  . PRO B  1 230 ? 194.293 189.517 204.926 1.00 81.09  ? 230 PRO A CA  1 
ATOM   3362 C C   . PRO B  1 230 ? 193.266 189.656 203.814 1.00 77.43  ? 230 PRO A C   1 
ATOM   3363 O O   . PRO B  1 230 ? 193.272 188.909 202.834 1.00 82.17  ? 230 PRO A O   1 
ATOM   3364 C CB  . PRO B  1 230 ? 195.578 190.289 204.602 1.00 80.00  ? 230 PRO A CB  1 
ATOM   3365 C CG  . PRO B  1 230 ? 196.689 189.402 205.067 1.00 76.08  ? 230 PRO A CG  1 
ATOM   3366 C CD  . PRO B  1 230 ? 196.203 188.005 204.847 1.00 76.52  ? 230 PRO A CD  1 
ATOM   3367 N N   . ALA B  1 231 ? 192.361 190.623 203.983 1.00 69.83  ? 231 ALA A N   1 
ATOM   3368 C CA  . ALA B  1 231 ? 191.344 190.860 202.965 1.00 76.98  ? 231 ALA A CA  1 
ATOM   3369 C C   . ALA B  1 231 ? 191.966 191.262 201.636 1.00 74.26  ? 231 ALA A C   1 
ATOM   3370 O O   . ALA B  1 231 ? 191.392 190.993 200.573 1.00 71.65  ? 231 ALA A O   1 
ATOM   3371 C CB  . ALA B  1 231 ? 190.363 191.932 203.439 1.00 72.60  ? 231 ALA A CB  1 
ATOM   3372 N N   . TRP B  1 232 ? 193.138 191.898 201.670 1.00 69.25  ? 232 TRP A N   1 
ATOM   3373 C CA  . TRP B  1 232 ? 193.794 192.290 200.429 1.00 65.62  ? 232 TRP A CA  1 
ATOM   3374 C C   . TRP B  1 232 ? 194.206 191.074 199.611 1.00 73.27  ? 232 TRP A C   1 
ATOM   3375 O O   . TRP B  1 232 ? 194.065 191.074 198.384 1.00 76.95  ? 232 TRP A O   1 
ATOM   3376 C CB  . TRP B  1 232 ? 194.999 193.178 200.726 1.00 67.68  ? 232 TRP A CB  1 
ATOM   3377 C CG  . TRP B  1 232 ? 194.689 194.634 200.605 1.00 74.54  ? 232 TRP A CG  1 
ATOM   3378 C CD1 . TRP B  1 232 ? 194.675 195.555 201.609 1.00 73.22  ? 232 TRP A CD1 1 
ATOM   3379 C CD2 . TRP B  1 232 ? 194.331 195.338 199.410 1.00 77.38  ? 232 TRP A CD2 1 
ATOM   3380 N NE1 . TRP B  1 232 ? 194.338 196.790 201.114 1.00 70.11  ? 232 TRP A NE1 1 
ATOM   3381 C CE2 . TRP B  1 232 ? 194.121 196.683 199.766 1.00 73.59  ? 232 TRP A CE2 1 
ATOM   3382 C CE3 . TRP B  1 232 ? 194.172 194.962 198.074 1.00 74.08  ? 232 TRP A CE3 1 
ATOM   3383 C CZ2 . TRP B  1 232 ? 193.762 197.653 198.834 1.00 69.11  ? 232 TRP A CZ2 1 
ATOM   3384 C CZ3 . TRP B  1 232 ? 193.813 195.927 197.152 1.00 71.09  ? 232 TRP A CZ3 1 
ATOM   3385 C CH2 . TRP B  1 232 ? 193.612 197.256 197.536 1.00 67.46  ? 232 TRP A CH2 1 
ATOM   3386 N N   . THR B  1 233 ? 194.707 190.022 200.263 1.00 66.97  ? 233 THR A N   1 
ATOM   3387 C CA  . THR B  1 233 ? 195.108 188.842 199.504 1.00 59.56  ? 233 THR A CA  1 
ATOM   3388 C C   . THR B  1 233 ? 193.898 188.075 198.984 1.00 61.23  ? 233 THR A C   1 
ATOM   3389 O O   . THR B  1 233 ? 193.973 187.460 197.915 1.00 69.17  ? 233 THR A O   1 
ATOM   3390 C CB  . THR B  1 233 ? 196.019 187.938 200.341 1.00 60.58  ? 233 THR A CB  1 
ATOM   3391 O OG1 . THR B  1 233 ? 196.801 187.113 199.469 1.00 65.86  ? 233 THR A OG1 1 
ATOM   3392 C CG2 . THR B  1 233 ? 195.221 187.042 201.265 1.00 58.33  ? 233 THR A CG2 1 
ATOM   3393 N N   . THR B  1 234 ? 192.773 188.113 199.705 1.00 50.70  ? 234 THR A N   1 
ATOM   3394 C CA  . THR B  1 234 ? 191.546 187.532 199.171 1.00 48.38  ? 234 THR A CA  1 
ATOM   3395 C C   . THR B  1 234 ? 191.072 188.298 197.944 1.00 56.62  ? 234 THR A C   1 
ATOM   3396 O O   . THR B  1 234 ? 190.651 187.697 196.947 1.00 56.79  ? 234 THR A O   1 
ATOM   3397 C CB  . THR B  1 234 ? 190.457 187.508 200.241 1.00 42.59  ? 234 THR A CB  1 
ATOM   3398 O OG1 . THR B  1 234 ? 191.024 187.103 201.492 1.00 49.65  ? 234 THR A OG1 1 
ATOM   3399 C CG2 . THR B  1 234 ? 189.370 186.530 199.853 1.00 40.49  ? 234 THR A CG2 1 
ATOM   3400 N N   . PHE B  1 235 ? 191.149 189.629 197.991 1.00 64.95  ? 235 PHE A N   1 
ATOM   3401 C CA  . PHE B  1 235 ? 190.830 190.414 196.805 1.00 61.85  ? 235 PHE A CA  1 
ATOM   3402 C C   . PHE B  1 235 ? 191.775 190.080 195.660 1.00 58.18  ? 235 PHE A C   1 
ATOM   3403 O O   . PHE B  1 235 ? 191.354 190.003 194.503 1.00 59.60  ? 235 PHE A O   1 
ATOM   3404 C CB  . PHE B  1 235 ? 190.886 191.907 197.122 1.00 52.69  ? 235 PHE A CB  1 
ATOM   3405 C CG  . PHE B  1 235 ? 191.030 192.771 195.905 1.00 52.38  ? 235 PHE A CG  1 
ATOM   3406 C CD1 . PHE B  1 235 ? 189.943 193.020 195.089 1.00 51.35  ? 235 PHE A CD1 1 
ATOM   3407 C CD2 . PHE B  1 235 ? 192.253 193.324 195.570 1.00 58.55  ? 235 PHE A CD2 1 
ATOM   3408 C CE1 . PHE B  1 235 ? 190.071 193.806 193.964 1.00 59.03  ? 235 PHE A CE1 1 
ATOM   3409 C CE2 . PHE B  1 235 ? 192.386 194.111 194.447 1.00 57.41  ? 235 PHE A CE2 1 
ATOM   3410 C CZ  . PHE B  1 235 ? 191.293 194.353 193.643 1.00 57.17  ? 235 PHE A CZ  1 
ATOM   3411 N N   . ARG B  1 236 ? 193.061 189.894 195.964 1.00 56.28  ? 236 ARG A N   1 
ATOM   3412 C CA  . ARG B  1 236 ? 194.035 189.595 194.919 1.00 53.66  ? 236 ARG A CA  1 
ATOM   3413 C C   . ARG B  1 236 ? 193.760 188.246 194.267 1.00 56.65  ? 236 ARG A C   1 
ATOM   3414 O O   . ARG B  1 236 ? 193.831 188.118 193.039 1.00 64.71  ? 236 ARG A O   1 
ATOM   3415 C CB  . ARG B  1 236 ? 195.450 189.634 195.491 1.00 56.19  ? 236 ARG A CB  1 
ATOM   3416 C CG  . ARG B  1 236 ? 196.257 190.839 195.052 1.00 57.27  ? 236 ARG A CG  1 
ATOM   3417 C CD  . ARG B  1 236 ? 197.726 190.671 195.382 1.00 59.74  ? 236 ARG A CD  1 
ATOM   3418 N NE  . ARG B  1 236 ? 198.070 191.295 196.652 1.00 64.27  ? 236 ARG A NE  1 
ATOM   3419 C CZ  . ARG B  1 236 ? 198.159 190.645 197.803 1.00 63.57  ? 236 ARG A CZ  1 
ATOM   3420 N NH1 . ARG B  1 236 ? 197.946 189.342 197.879 1.00 60.57  ? 236 ARG A NH1 1 
ATOM   3421 N NH2 . ARG B  1 236 ? 198.472 191.318 198.906 1.00 62.64  ? 236 ARG A NH2 1 
ATOM   3422 N N   . VAL B  1 237 ? 193.452 187.222 195.068 1.00 57.87  ? 237 VAL A N   1 
ATOM   3423 C CA  . VAL B  1 237 ? 193.169 185.915 194.482 1.00 61.07  ? 237 VAL A CA  1 
ATOM   3424 C C   . VAL B  1 237 ? 191.871 185.961 193.687 1.00 62.66  ? 237 VAL A C   1 
ATOM   3425 O O   . VAL B  1 237 ? 191.764 185.342 192.623 1.00 62.90  ? 237 VAL A O   1 
ATOM   3426 C CB  . VAL B  1 237 ? 193.149 184.805 195.551 1.00 50.40  ? 237 VAL A CB  1 
ATOM   3427 C CG1 . VAL B  1 237 ? 192.198 185.129 196.658 1.00 56.76  ? 237 VAL A CG1 1 
ATOM   3428 C CG2 . VAL B  1 237 ? 192.758 183.487 194.920 1.00 49.47  ? 237 VAL A CG2 1 
ATOM   3429 N N   . GLY B  1 238 ? 190.874 186.709 194.168 1.00 52.76  ? 238 GLY A N   1 
ATOM   3430 C CA  . GLY B  1 238 ? 189.668 186.889 193.376 1.00 52.83  ? 238 GLY A CA  1 
ATOM   3431 C C   . GLY B  1 238 ? 189.944 187.571 192.050 1.00 52.66  ? 238 GLY A C   1 
ATOM   3432 O O   . GLY B  1 238 ? 189.445 187.146 191.005 1.00 57.62  ? 238 GLY A O   1 
ATOM   3433 N N   . LEU B  1 239 ? 190.755 188.629 192.075 1.00 48.92  ? 239 LEU A N   1 
ATOM   3434 C CA  . LEU B  1 239 ? 191.110 189.343 190.854 1.00 52.49  ? 239 LEU A CA  1 
ATOM   3435 C C   . LEU B  1 239 ? 191.814 188.423 189.869 1.00 55.19  ? 239 LEU A C   1 
ATOM   3436 O O   . LEU B  1 239 ? 191.475 188.386 188.680 1.00 60.07  ? 239 LEU A O   1 
ATOM   3437 C CB  . LEU B  1 239 ? 191.997 190.539 191.206 1.00 55.03  ? 239 LEU A CB  1 
ATOM   3438 C CG  . LEU B  1 239 ? 192.893 191.141 190.125 1.00 52.91  ? 239 LEU A CG  1 
ATOM   3439 C CD1 . LEU B  1 239 ? 192.115 192.104 189.257 1.00 55.05  ? 239 LEU A CD1 1 
ATOM   3440 C CD2 . LEU B  1 239 ? 194.087 191.834 190.752 1.00 55.72  ? 239 LEU A CD2 1 
ATOM   3441 N N   . PHE B  1 240 ? 192.794 187.661 190.355 1.00 56.53  ? 240 PHE A N   1 
ATOM   3442 C CA  . PHE B  1 240 ? 193.548 186.777 189.476 1.00 51.62  ? 240 PHE A CA  1 
ATOM   3443 C C   . PHE B  1 240 ? 192.671 185.660 188.929 1.00 52.33  ? 240 PHE A C   1 
ATOM   3444 O O   . PHE B  1 240 ? 192.785 185.298 187.755 1.00 59.52  ? 240 PHE A O   1 
ATOM   3445 C CB  . PHE B  1 240 ? 194.756 186.212 190.215 1.00 50.81  ? 240 PHE A CB  1 
ATOM   3446 C CG  . PHE B  1 240 ? 195.865 187.204 190.391 1.00 54.29  ? 240 PHE A CG  1 
ATOM   3447 C CD1 . PHE B  1 240 ? 196.260 188.007 189.337 1.00 51.72  ? 240 PHE A CD1 1 
ATOM   3448 C CD2 . PHE B  1 240 ? 196.508 187.338 191.606 1.00 55.31  ? 240 PHE A CD2 1 
ATOM   3449 C CE1 . PHE B  1 240 ? 197.276 188.922 189.493 1.00 51.07  ? 240 PHE A CE1 1 
ATOM   3450 C CE2 . PHE B  1 240 ? 197.524 188.252 191.766 1.00 54.01  ? 240 PHE A CE2 1 
ATOM   3451 C CZ  . PHE B  1 240 ? 197.909 189.045 190.708 1.00 51.23  ? 240 PHE A CZ  1 
ATOM   3452 N N   . CYS B  1 241 ? 191.775 185.114 189.754 1.00 51.31  ? 241 CYS A N   1 
ATOM   3453 C CA  . CYS B  1 241 ? 190.887 184.059 189.281 1.00 55.34  ? 241 CYS A CA  1 
ATOM   3454 C C   . CYS B  1 241 ? 189.911 184.581 188.235 1.00 56.99  ? 241 CYS A C   1 
ATOM   3455 O O   . CYS B  1 241 ? 189.627 183.893 187.249 1.00 58.84  ? 241 CYS A O   1 
ATOM   3456 C CB  . CYS B  1 241 ? 190.139 183.443 190.461 1.00 59.55  ? 241 CYS A CB  1 
ATOM   3457 S SG  . CYS B  1 241 ? 191.071 182.150 191.308 1.00 86.33  ? 241 CYS A SG  1 
ATOM   3458 N N   . GLY B  1 242 ? 189.388 185.794 188.425 1.00 50.68  ? 242 GLY A N   1 
ATOM   3459 C CA  . GLY B  1 242 ? 188.503 186.366 187.424 1.00 48.32  ? 242 GLY A CA  1 
ATOM   3460 C C   . GLY B  1 242 ? 189.212 186.662 186.117 1.00 51.44  ? 242 GLY A C   1 
ATOM   3461 O O   . GLY B  1 242 ? 188.686 186.379 185.033 1.00 53.84  ? 242 GLY A O   1 
ATOM   3462 N N   . ILE B  1 243 ? 190.415 187.236 186.198 1.00 46.17  ? 243 ILE A N   1 
ATOM   3463 C CA  . ILE B  1 243 ? 191.203 187.470 184.993 1.00 45.67  ? 243 ILE A CA  1 
ATOM   3464 C C   . ILE B  1 243 ? 191.501 186.149 184.299 1.00 54.75  ? 243 ILE A C   1 
ATOM   3465 O O   . ILE B  1 243 ? 191.457 186.053 183.068 1.00 56.67  ? 243 ILE A O   1 
ATOM   3466 C CB  . ILE B  1 243 ? 192.491 188.241 185.336 1.00 44.19  ? 243 ILE A CB  1 
ATOM   3467 C CG1 . ILE B  1 243 ? 192.157 189.619 185.906 1.00 48.80  ? 243 ILE A CG1 1 
ATOM   3468 C CG2 . ILE B  1 243 ? 193.369 188.396 184.109 1.00 52.28  ? 243 ILE A CG2 1 
ATOM   3469 C CD1 . ILE B  1 243 ? 193.366 190.502 186.112 1.00 48.32  ? 243 ILE A CD1 1 
ATOM   3470 N N   . PHE B  1 244 ? 191.781 185.103 185.080 1.00 56.21  ? 244 PHE A N   1 
ATOM   3471 C CA  . PHE B  1 244 ? 192.040 183.786 184.513 1.00 49.78  ? 244 PHE A CA  1 
ATOM   3472 C C   . PHE B  1 244 ? 190.811 183.237 183.805 1.00 57.56  ? 244 PHE A C   1 
ATOM   3473 O O   . PHE B  1 244 ? 190.918 182.680 182.711 1.00 64.49  ? 244 PHE A O   1 
ATOM   3474 C CB  . PHE B  1 244 ? 192.500 182.836 185.617 1.00 53.44  ? 244 PHE A CB  1 
ATOM   3475 C CG  . PHE B  1 244 ? 192.963 181.501 185.118 1.00 53.22  ? 244 PHE A CG  1 
ATOM   3476 C CD1 . PHE B  1 244 ? 194.100 181.394 184.340 1.00 51.92  ? 244 PHE A CD1 1 
ATOM   3477 C CD2 . PHE B  1 244 ? 192.270 180.350 185.443 1.00 50.14  ? 244 PHE A CD2 1 
ATOM   3478 C CE1 . PHE B  1 244 ? 194.530 180.168 183.886 1.00 53.25  ? 244 PHE A CE1 1 
ATOM   3479 C CE2 . PHE B  1 244 ? 192.696 179.122 184.992 1.00 57.05  ? 244 PHE A CE2 1 
ATOM   3480 C CZ  . PHE B  1 244 ? 193.827 179.031 184.211 1.00 59.61  ? 244 PHE A CZ  1 
ATOM   3481 N N   . ILE B  1 245 ? 189.633 183.394 184.411 1.00 58.00  ? 245 ILE A N   1 
ATOM   3482 C CA  . ILE B  1 245 ? 188.406 182.888 183.799 1.00 56.43  ? 245 ILE A CA  1 
ATOM   3483 C C   . ILE B  1 245 ? 188.142 183.592 182.474 1.00 55.76  ? 245 ILE A C   1 
ATOM   3484 O O   . ILE B  1 245 ? 187.852 182.951 181.454 1.00 58.92  ? 245 ILE A O   1 
ATOM   3485 C CB  . ILE B  1 245 ? 187.220 183.050 184.766 1.00 50.68  ? 245 ILE A CB  1 
ATOM   3486 C CG1 . ILE B  1 245 ? 187.318 182.039 185.907 1.00 52.25  ? 245 ILE A CG1 1 
ATOM   3487 C CG2 . ILE B  1 245 ? 185.903 182.891 184.027 1.00 47.67  ? 245 ILE A CG2 1 
ATOM   3488 C CD1 . ILE B  1 245 ? 186.196 182.151 186.909 1.00 53.91  ? 245 ILE A CD1 1 
ATOM   3489 N N   . VAL B  1 246 ? 188.244 184.923 182.466 1.00 46.53  ? 246 VAL A N   1 
ATOM   3490 C CA  . VAL B  1 246 ? 187.954 185.657 181.237 1.00 48.08  ? 246 VAL A CA  1 
ATOM   3491 C C   . VAL B  1 246 ? 188.999 185.357 180.171 1.00 52.28  ? 246 VAL A C   1 
ATOM   3492 O O   . VAL B  1 246 ? 188.666 185.183 178.992 1.00 56.14  ? 246 VAL A O   1 
ATOM   3493 C CB  . VAL B  1 246 ? 187.844 187.166 181.510 1.00 45.25  ? 246 VAL A CB  1 
ATOM   3494 C CG1 . VAL B  1 246 ? 187.334 187.877 180.272 1.00 43.87  ? 246 VAL A CG1 1 
ATOM   3495 C CG2 . VAL B  1 246 ? 186.913 187.410 182.659 1.00 51.45  ? 246 VAL A CG2 1 
ATOM   3496 N N   . LEU B  1 247 ? 190.275 185.290 180.558 1.00 52.60  ? 247 LEU A N   1 
ATOM   3497 C CA  . LEU B  1 247 ? 191.320 184.976 179.593 1.00 48.91  ? 247 LEU A CA  1 
ATOM   3498 C C   . LEU B  1 247 ? 191.153 183.567 179.045 1.00 60.49  ? 247 LEU A C   1 
ATOM   3499 O O   . LEU B  1 247 ? 191.425 183.319 177.869 1.00 69.90  ? 247 LEU A O   1 
ATOM   3500 C CB  . LEU B  1 247 ? 192.696 185.147 180.235 1.00 47.26  ? 247 LEU A CB  1 
ATOM   3501 C CG  . LEU B  1 247 ? 193.237 186.575 180.285 1.00 44.42  ? 247 LEU A CG  1 
ATOM   3502 C CD1 . LEU B  1 247 ? 194.506 186.639 181.109 1.00 51.37  ? 247 LEU A CD1 1 
ATOM   3503 C CD2 . LEU B  1 247 ? 193.490 187.091 178.888 1.00 45.77  ? 247 LEU A CD2 1 
ATOM   3504 N N   . ASN B  1 248 ? 190.694 182.632 179.879 1.00 64.15  ? 248 ASN A N   1 
ATOM   3505 C CA  . ASN B  1 248 ? 190.462 181.268 179.421 1.00 55.98  ? 248 ASN A CA  1 
ATOM   3506 C C   . ASN B  1 248 ? 189.310 181.203 178.430 1.00 62.81  ? 248 ASN A C   1 
ATOM   3507 O O   . ASN B  1 248 ? 189.392 180.493 177.421 1.00 66.36  ? 248 ASN A O   1 
ATOM   3508 C CB  . ASN B  1 248 ? 190.191 180.364 180.619 1.00 51.35  ? 248 ASN A CB  1 
ATOM   3509 C CG  . ASN B  1 248 ? 191.391 179.539 181.002 1.00 59.71  ? 248 ASN A CG  1 
ATOM   3510 O OD1 . ASN B  1 248 ? 192.402 179.534 180.302 1.00 63.80  ? 248 ASN A OD1 1 
ATOM   3511 N ND2 . ASN B  1 248 ? 191.300 178.854 182.132 1.00 66.70  ? 248 ASN A ND2 1 
ATOM   3512 N N   . ILE B  1 249 ? 188.222 181.927 178.705 1.00 57.57  ? 249 ILE A N   1 
ATOM   3513 C CA  . ILE B  1 249 ? 187.107 181.953 177.761 1.00 58.51  ? 249 ILE A CA  1 
ATOM   3514 C C   . ILE B  1 249 ? 187.541 182.594 176.449 1.00 59.07  ? 249 ILE A C   1 
ATOM   3515 O O   . ILE B  1 249 ? 187.199 182.114 175.359 1.00 62.10  ? 249 ILE A O   1 
ATOM   3516 C CB  . ILE B  1 249 ? 185.894 182.672 178.375 1.00 53.71  ? 249 ILE A CB  1 
ATOM   3517 C CG1 . ILE B  1 249 ? 185.421 181.932 179.626 1.00 55.96  ? 249 ILE A CG1 1 
ATOM   3518 C CG2 . ILE B  1 249 ? 184.769 182.769 177.360 1.00 49.54  ? 249 ILE A CG2 1 
ATOM   3519 C CD1 . ILE B  1 249 ? 184.119 182.447 180.192 1.00 58.84  ? 249 ILE A CD1 1 
ATOM   3520 N N   . THR B  1 250 ? 188.313 183.681 176.532 1.00 58.96  ? 250 THR A N   1 
ATOM   3521 C CA  . THR B  1 250 ? 188.834 184.318 175.327 1.00 61.94  ? 250 THR A CA  1 
ATOM   3522 C C   . THR B  1 250 ? 189.746 183.374 174.557 1.00 59.56  ? 250 THR A C   1 
ATOM   3523 O O   . THR B  1 250 ? 189.711 183.335 173.325 1.00 60.44  ? 250 THR A O   1 
ATOM   3524 C CB  . THR B  1 250 ? 189.589 185.596 175.691 1.00 59.70  ? 250 THR A CB  1 
ATOM   3525 O OG1 . THR B  1 250 ? 188.811 186.368 176.613 1.00 70.35  ? 250 THR A OG1 1 
ATOM   3526 C CG2 . THR B  1 250 ? 189.858 186.421 174.446 1.00 62.44  ? 250 THR A CG2 1 
ATOM   3527 N N   . LEU B  1 251 ? 190.575 182.613 175.270 1.00 63.83  ? 251 LEU A N   1 
ATOM   3528 C CA  . LEU B  1 251 ? 191.485 181.670 174.633 1.00 66.25  ? 251 LEU A CA  1 
ATOM   3529 C C   . LEU B  1 251 ? 190.720 180.563 173.922 1.00 66.34  ? 251 LEU A C   1 
ATOM   3530 O O   . LEU B  1 251 ? 191.049 180.205 172.786 1.00 70.56  ? 251 LEU A O   1 
ATOM   3531 C CB  . LEU B  1 251 ? 192.427 181.098 175.691 1.00 62.76  ? 251 LEU A CB  1 
ATOM   3532 C CG  . LEU B  1 251 ? 193.771 180.479 175.324 1.00 56.32  ? 251 LEU A CG  1 
ATOM   3533 C CD1 . LEU B  1 251 ? 194.610 180.411 176.579 1.00 61.29  ? 251 LEU A CD1 1 
ATOM   3534 C CD2 . LEU B  1 251 ? 193.601 179.093 174.738 1.00 61.77  ? 251 LEU A CD2 1 
ATOM   3535 N N   . VAL B  1 252 ? 189.693 180.015 174.573 1.00 58.90  ? 252 VAL A N   1 
ATOM   3536 C CA  . VAL B  1 252 ? 188.875 178.982 173.944 1.00 56.96  ? 252 VAL A CA  1 
ATOM   3537 C C   . VAL B  1 252 ? 188.192 179.530 172.698 1.00 63.44  ? 252 VAL A C   1 
ATOM   3538 O O   . VAL B  1 252 ? 188.185 178.885 171.640 1.00 60.02  ? 252 VAL A O   1 
ATOM   3539 C CB  . VAL B  1 252 ? 187.852 178.427 174.952 1.00 53.95  ? 252 VAL A CB  1 
ATOM   3540 C CG1 . VAL B  1 252 ? 186.806 177.589 174.241 1.00 57.87  ? 252 VAL A CG1 1 
ATOM   3541 C CG2 . VAL B  1 252 ? 188.553 177.614 176.025 1.00 59.68  ? 252 VAL A CG2 1 
ATOM   3542 N N   . LEU B  1 253 ? 187.613 180.730 172.801 1.00 74.70  ? 253 LEU A N   1 
ATOM   3543 C CA  . LEU B  1 253 ? 186.918 181.318 171.661 1.00 71.26  ? 253 LEU A CA  1 
ATOM   3544 C C   . LEU B  1 253 ? 187.879 181.612 170.517 1.00 69.27  ? 253 LEU A C   1 
ATOM   3545 O O   . LEU B  1 253 ? 187.550 181.385 169.349 1.00 70.61  ? 253 LEU A O   1 
ATOM   3546 C CB  . LEU B  1 253 ? 186.183 182.586 172.090 1.00 62.16  ? 253 LEU A CB  1 
ATOM   3547 C CG  . LEU B  1 253 ? 184.677 182.431 172.302 1.00 63.78  ? 253 LEU A CG  1 
ATOM   3548 C CD1 . LEU B  1 253 ? 184.386 181.376 173.353 1.00 66.20  ? 253 LEU A CD1 1 
ATOM   3549 C CD2 . LEU B  1 253 ? 184.068 183.757 172.703 1.00 72.41  ? 253 LEU A CD2 1 
ATOM   3550 N N   . ALA B  1 254 ? 189.071 182.121 170.832 1.00 73.28  ? 254 ALA A N   1 
ATOM   3551 C CA  . ALA B  1 254 ? 190.068 182.367 169.799 1.00 78.17  ? 254 ALA A CA  1 
ATOM   3552 C C   . ALA B  1 254 ? 190.494 181.069 169.132 1.00 80.88  ? 254 ALA A C   1 
ATOM   3553 O O   . ALA B  1 254 ? 190.641 181.016 167.907 1.00 84.53  ? 254 ALA A O   1 
ATOM   3554 C CB  . ALA B  1 254 ? 191.277 183.088 170.395 1.00 78.23  ? 254 ALA A CB  1 
ATOM   3555 N N   . ALA B  1 255 ? 190.677 180.008 169.920 1.00 81.44  ? 255 ALA A N   1 
ATOM   3556 C CA  . ALA B  1 255 ? 191.065 178.725 169.350 1.00 83.90  ? 255 ALA A CA  1 
ATOM   3557 C C   . ALA B  1 255 ? 190.000 178.195 168.400 1.00 90.55  ? 255 ALA A C   1 
ATOM   3558 O O   . ALA B  1 255 ? 190.321 177.716 167.306 1.00 94.66  ? 255 ALA A O   1 
ATOM   3559 C CB  . ALA B  1 255 ? 191.336 177.718 170.467 1.00 84.81  ? 255 ALA A CB  1 
ATOM   3560 N N   . VAL B  1 256 ? 188.727 178.271 168.792 1.00 89.79  ? 256 VAL A N   1 
ATOM   3561 C CA  . VAL B  1 256 ? 187.698 177.705 167.923 1.00 87.10  ? 256 VAL A CA  1 
ATOM   3562 C C   . VAL B  1 256 ? 187.455 178.591 166.701 1.00 89.17  ? 256 VAL A C   1 
ATOM   3563 O O   . VAL B  1 256 ? 187.260 178.078 165.593 1.00 91.34  ? 256 VAL A O   1 
ATOM   3564 C CB  . VAL B  1 256 ? 186.391 177.438 168.693 1.00 84.01  ? 256 VAL A CB  1 
ATOM   3565 C CG1 . VAL B  1 256 ? 185.987 178.632 169.517 1.00 86.42  ? 256 VAL A CG1 1 
ATOM   3566 C CG2 . VAL B  1 256 ? 185.273 177.034 167.741 1.00 86.58  ? 256 VAL A CG2 1 
ATOM   3567 N N   . PHE B  1 257 ? 187.484 179.918 166.856 1.00 90.03  ? 257 PHE A N   1 
ATOM   3568 C CA  . PHE B  1 257 ? 187.115 180.829 165.776 1.00 89.13  ? 257 PHE A CA  1 
ATOM   3569 C C   . PHE B  1 257 ? 188.313 181.257 164.935 1.00 91.91  ? 257 PHE A C   1 
ATOM   3570 O O   . PHE B  1 257 ? 188.371 180.963 163.738 1.00 93.29  ? 257 PHE A O   1 
ATOM   3571 C CB  . PHE B  1 257 ? 186.417 182.067 166.354 1.00 87.66  ? 257 PHE A CB  1 
ATOM   3572 C CG  . PHE B  1 257 ? 184.961 181.863 166.644 1.00 91.27  ? 257 PHE A CG  1 
ATOM   3573 C CD1 . PHE B  1 257 ? 184.009 182.102 165.671 1.00 93.69  ? 257 PHE A CD1 1 
ATOM   3574 C CD2 . PHE B  1 257 ? 184.544 181.442 167.893 1.00 91.82  ? 257 PHE A CD2 1 
ATOM   3575 C CE1 . PHE B  1 257 ? 182.667 181.917 165.936 1.00 93.52  ? 257 PHE A CE1 1 
ATOM   3576 C CE2 . PHE B  1 257 ? 183.205 181.255 168.166 1.00 91.08  ? 257 PHE A CE2 1 
ATOM   3577 C CZ  . PHE B  1 257 ? 182.265 181.493 167.186 1.00 91.69  ? 257 PHE A CZ  1 
ATOM   3578 N N   . LYS B  1 258 ? 189.277 181.946 165.541 1.00 94.20  ? 258 LYS A N   1 
ATOM   3579 C CA  . LYS B  1 258 ? 190.398 182.536 164.813 1.00 94.08  ? 258 LYS A CA  1 
ATOM   3580 C C   . LYS B  1 258 ? 191.537 181.525 164.806 1.00 96.78  ? 258 LYS A C   1 
ATOM   3581 O O   . LYS B  1 258 ? 192.389 181.524 165.697 1.00 95.67  ? 258 LYS A O   1 
ATOM   3582 C CB  . LYS B  1 258 ? 190.825 183.858 165.443 1.00 94.17  ? 258 LYS A CB  1 
ATOM   3583 C CG  . LYS B  1 258 ? 191.820 184.652 164.605 1.00 96.67  ? 258 LYS A CG  1 
ATOM   3584 C CD  . LYS B  1 258 ? 193.254 184.456 165.074 1.00 97.56  ? 258 LYS A CD  1 
ATOM   3585 C CE  . LYS B  1 258 ? 194.183 185.495 164.469 1.00 97.06  ? 258 LYS A CE  1 
ATOM   3586 N NZ  . LYS B  1 258 ? 195.605 185.054 164.518 1.00 94.46  ? 258 LYS A NZ  1 
ATOM   3587 N N   . LEU B  1 259 ? 191.538 180.655 163.802 1.00 113.46 ? 259 LEU A N   1 
ATOM   3588 C CA  . LEU B  1 259 ? 192.632 179.718 163.597 1.00 112.73 ? 259 LEU A CA  1 
ATOM   3589 C C   . LEU B  1 259 ? 192.584 179.241 162.153 1.00 113.32 ? 259 LEU A C   1 
ATOM   3590 O O   . LEU B  1 259 ? 191.560 179.349 161.474 1.00 114.43 ? 259 LEU A O   1 
ATOM   3591 C CB  . LEU B  1 259 ? 192.562 178.540 164.574 1.00 109.31 ? 259 LEU A CB  1 
ATOM   3592 C CG  . LEU B  1 259 ? 193.918 177.983 165.018 1.00 109.66 ? 259 LEU A CG  1 
ATOM   3593 C CD1 . LEU B  1 259 ? 194.858 179.108 165.424 1.00 110.32 ? 259 LEU A CD1 1 
ATOM   3594 C CD2 . LEU B  1 259 ? 193.750 176.991 166.156 1.00 107.27 ? 259 LEU A CD2 1 
ATOM   3595 N N   . GLU B  1 260 ? 193.714 178.718 161.691 1.00 122.37 ? 260 GLU A N   1 
ATOM   3596 C CA  . GLU B  1 260 ? 193.856 178.208 160.334 1.00 123.14 ? 260 GLU A CA  1 
ATOM   3597 C C   . GLU B  1 260 ? 194.377 176.778 160.394 1.00 123.86 ? 260 GLU A C   1 
ATOM   3598 O O   . GLU B  1 260 ? 195.305 176.477 161.154 1.00 122.50 ? 260 GLU A O   1 
ATOM   3599 C CB  . GLU B  1 260 ? 194.757 179.133 159.507 1.00 123.58 ? 260 GLU A CB  1 
ATOM   3600 C CG  . GLU B  1 260 ? 196.212 178.748 159.445 1.00 124.51 ? 260 GLU A CG  1 
ATOM   3601 C CD  . GLU B  1 260 ? 196.939 179.121 160.722 1.00 125.41 ? 260 GLU A CD  1 
ATOM   3602 O OE1 . GLU B  1 260 ? 198.086 178.676 160.909 1.00 124.17 ? 260 GLU A OE1 1 
ATOM   3603 O OE2 . GLU B  1 260 ? 196.360 179.864 161.543 1.00 124.81 ? 260 GLU A OE2 1 
ATOM   3604 N N   . THR B  1 261 ? 193.735 175.891 159.639 1.00 135.13 ? 261 THR A N   1 
ATOM   3605 C CA  . THR B  1 261 ? 193.994 174.452 159.702 1.00 135.43 ? 261 THR A CA  1 
ATOM   3606 C C   . THR B  1 261 ? 194.929 173.979 158.591 1.00 135.25 ? 261 THR A C   1 
ATOM   3607 O O   . THR B  1 261 ? 194.552 173.164 157.751 1.00 135.90 ? 261 THR A O   1 
ATOM   3608 C CB  . THR B  1 261 ? 192.673 173.694 159.656 1.00 134.43 ? 261 THR A CB  1 
ATOM   3609 O OG1 . THR B  1 261 ? 192.071 173.859 158.366 1.00 134.39 ? 261 THR A OG1 1 
ATOM   3610 C CG2 . THR B  1 261 ? 191.723 174.222 160.720 1.00 133.43 ? 261 THR A CG2 1 
ATOM   3611 N N   . ASP B  1 262 ? 196.164 174.484 158.573 1.00 131.35 ? 262 ASP A N   1 
ATOM   3612 C CA  . ASP B  1 262 ? 197.158 174.012 157.620 1.00 131.89 ? 262 ASP A CA  1 
ATOM   3613 C C   . ASP B  1 262 ? 198.456 173.568 158.277 1.00 130.64 ? 262 ASP A C   1 
ATOM   3614 O O   . ASP B  1 262 ? 199.265 172.902 157.621 1.00 129.65 ? 262 ASP A O   1 
ATOM   3615 C CB  . ASP B  1 262 ? 197.467 175.095 156.573 1.00 132.17 ? 262 ASP A CB  1 
ATOM   3616 C CG  . ASP B  1 262 ? 198.171 176.299 157.166 1.00 131.70 ? 262 ASP A CG  1 
ATOM   3617 O OD1 . ASP B  1 262 ? 198.110 176.483 158.400 1.00 131.41 ? 262 ASP A OD1 1 
ATOM   3618 O OD2 . ASP B  1 262 ? 198.791 177.062 156.396 1.00 132.52 ? 262 ASP A OD2 1 
ATOM   3619 N N   . ARG B  1 263 ? 198.678 173.911 159.543 1.00 120.05 ? 263 ARG A N   1 
ATOM   3620 C CA  . ARG B  1 263 ? 199.875 173.520 160.269 1.00 118.46 ? 263 ARG A CA  1 
ATOM   3621 C C   . ARG B  1 263 ? 199.464 172.804 161.547 1.00 117.01 ? 263 ARG A C   1 
ATOM   3622 O O   . ARG B  1 263 ? 198.353 172.989 162.051 1.00 116.01 ? 263 ARG A O   1 
ATOM   3623 C CB  . ARG B  1 263 ? 200.752 174.731 160.611 1.00 117.51 ? 263 ARG A CB  1 
ATOM   3624 C CG  . ARG B  1 263 ? 199.966 175.945 161.062 1.00 119.21 ? 263 ARG A CG  1 
ATOM   3625 C CD  . ARG B  1 263 ? 200.760 177.241 160.946 1.00 120.95 ? 263 ARG A CD  1 
ATOM   3626 N NE  . ARG B  1 263 ? 201.144 177.585 159.583 1.00 121.31 ? 263 ARG A NE  1 
ATOM   3627 C CZ  . ARG B  1 263 ? 202.377 177.898 159.209 1.00 121.00 ? 263 ARG A CZ  1 
ATOM   3628 N NH1 . ARG B  1 263 ? 203.386 177.870 160.063 1.00 118.83 ? 263 ARG A NH1 1 
ATOM   3629 N NH2 . ARG B  1 263 ? 202.598 178.268 157.951 1.00 119.76 ? 263 ARG A NH2 1 
ATOM   3630 N N   . SER B  1 264 ? 200.371 171.982 162.068 1.00 102.96 ? 264 SER A N   1 
ATOM   3631 C CA  . SER B  1 264 ? 200.082 171.188 163.255 1.00 102.18 ? 264 SER A CA  1 
ATOM   3632 C C   . SER B  1 264 ? 200.129 172.072 164.495 1.00 101.23 ? 264 SER A C   1 
ATOM   3633 O O   . SER B  1 264 ? 201.135 172.742 164.751 1.00 102.05 ? 264 SER A O   1 
ATOM   3634 C CB  . SER B  1 264 ? 201.074 170.034 163.378 1.00 101.19 ? 264 SER A CB  1 
ATOM   3635 O OG  . SER B  1 264 ? 200.631 169.085 164.333 1.00 97.38  ? 264 SER A OG  1 
ATOM   3636 N N   . ILE B  1 265 ? 199.033 172.075 165.262 1.00 82.09  ? 265 ILE A N   1 
ATOM   3637 C CA  . ILE B  1 265 ? 198.991 172.776 166.544 1.00 80.23  ? 265 ILE A CA  1 
ATOM   3638 C C   . ILE B  1 265 ? 199.634 171.973 167.660 1.00 80.49  ? 265 ILE A C   1 
ATOM   3639 O O   . ILE B  1 265 ? 199.784 172.485 168.777 1.00 82.01  ? 265 ILE A O   1 
ATOM   3640 C CB  . ILE B  1 265 ? 197.531 173.111 166.915 1.00 83.31  ? 265 ILE A CB  1 
ATOM   3641 C CG1 . ILE B  1 265 ? 197.468 174.266 167.918 1.00 83.24  ? 265 ILE A CG1 1 
ATOM   3642 C CG2 . ILE B  1 265 ? 196.828 171.883 167.467 1.00 83.19  ? 265 ILE A CG2 1 
ATOM   3643 C CD1 . ILE B  1 265 ? 196.076 174.814 168.129 1.00 83.04  ? 265 ILE A CD1 1 
ATOM   3644 N N   . TRP B  1 266 ? 200.028 170.730 167.388 1.00 82.24  ? 266 TRP A N   1 
ATOM   3645 C CA  . TRP B  1 266 ? 200.533 169.860 168.446 1.00 82.71  ? 266 TRP A CA  1 
ATOM   3646 C C   . TRP B  1 266 ? 201.792 170.370 169.136 1.00 83.02  ? 266 TRP A C   1 
ATOM   3647 O O   . TRP B  1 266 ? 201.889 170.201 170.364 1.00 89.93  ? 266 TRP A O   1 
ATOM   3648 C CB  . TRP B  1 266 ? 200.743 168.447 167.890 1.00 82.57  ? 266 TRP A CB  1 
ATOM   3649 C CG  . TRP B  1 266 ? 199.477 167.664 167.884 1.00 84.91  ? 266 TRP A CG  1 
ATOM   3650 C CD1 . TRP B  1 266 ? 198.870 167.092 166.806 1.00 86.54  ? 266 TRP A CD1 1 
ATOM   3651 C CD2 . TRP B  1 266 ? 198.641 167.386 169.012 1.00 82.06  ? 266 TRP A CD2 1 
ATOM   3652 N NE1 . TRP B  1 266 ? 197.712 166.466 167.195 1.00 84.72  ? 266 TRP A NE1 1 
ATOM   3653 C CE2 . TRP B  1 266 ? 197.550 166.632 168.545 1.00 86.56  ? 266 TRP A CE2 1 
ATOM   3654 C CE3 . TRP B  1 266 ? 198.714 167.694 170.374 1.00 79.69  ? 266 TRP A CE3 1 
ATOM   3655 C CZ2 . TRP B  1 266 ? 196.540 166.185 169.389 1.00 90.31  ? 266 TRP A CZ2 1 
ATOM   3656 C CZ3 . TRP B  1 266 ? 197.710 167.250 171.208 1.00 81.81  ? 266 TRP A CZ3 1 
ATOM   3657 C CH2 . TRP B  1 266 ? 196.638 166.503 170.715 1.00 86.91  ? 266 TRP A CH2 1 
ATOM   3658 N N   . PRO B  1 267 ? 202.791 170.936 168.448 1.00 73.02  ? 267 PRO A N   1 
ATOM   3659 C CA  . PRO B  1 267 ? 203.933 171.490 169.195 1.00 72.52  ? 267 PRO A CA  1 
ATOM   3660 C C   . PRO B  1 267 ? 203.526 172.508 170.243 1.00 71.64  ? 267 PRO A C   1 
ATOM   3661 O O   . PRO B  1 267 ? 204.046 172.472 171.363 1.00 73.77  ? 267 PRO A O   1 
ATOM   3662 C CB  . PRO B  1 267 ? 204.794 172.117 168.092 1.00 70.21  ? 267 PRO A CB  1 
ATOM   3663 C CG  . PRO B  1 267 ? 204.499 171.302 166.897 1.00 77.39  ? 267 PRO A CG  1 
ATOM   3664 C CD  . PRO B  1 267 ? 203.044 170.943 166.995 1.00 77.07  ? 267 PRO A CD  1 
ATOM   3665 N N   . LEU B  1 268 ? 202.580 173.395 169.926 1.00 63.78  ? 268 LEU A N   1 
ATOM   3666 C CA  . LEU B  1 268 ? 202.127 174.379 170.905 1.00 65.57  ? 268 LEU A CA  1 
ATOM   3667 C C   . LEU B  1 268 ? 201.466 173.706 172.101 1.00 63.82  ? 268 LEU A C   1 
ATOM   3668 O O   . LEU B  1 268 ? 201.702 174.091 173.256 1.00 62.03  ? 268 LEU A O   1 
ATOM   3669 C CB  . LEU B  1 268 ? 201.162 175.359 170.241 1.00 60.05  ? 268 LEU A CB  1 
ATOM   3670 C CG  . LEU B  1 268 ? 200.858 176.656 170.986 1.00 53.74  ? 268 LEU A CG  1 
ATOM   3671 C CD1 . LEU B  1 268 ? 201.948 177.674 170.726 1.00 56.17  ? 268 LEU A CD1 1 
ATOM   3672 C CD2 . LEU B  1 268 ? 199.506 177.195 170.560 1.00 62.63  ? 268 LEU A CD2 1 
ATOM   3673 N N   . ILE B  1 269 ? 200.631 172.698 171.841 1.00 61.60  ? 269 ILE A N   1 
ATOM   3674 C CA  . ILE B  1 269 ? 199.966 171.975 172.919 1.00 58.44  ? 269 ILE A CA  1 
ATOM   3675 C C   . ILE B  1 269 ? 200.994 171.309 173.819 1.00 53.90  ? 269 ILE A C   1 
ATOM   3676 O O   . ILE B  1 269 ? 200.889 171.356 175.049 1.00 58.82  ? 269 ILE A O   1 
ATOM   3677 C CB  . ILE B  1 269 ? 198.974 170.949 172.339 1.00 56.02  ? 269 ILE A CB  1 
ATOM   3678 C CG1 . ILE B  1 269 ? 197.814 171.659 171.638 1.00 56.57  ? 269 ILE A CG1 1 
ATOM   3679 C CG2 . ILE B  1 269 ? 198.459 170.031 173.428 1.00 56.59  ? 269 ILE A CG2 1 
ATOM   3680 C CD1 . ILE B  1 269 ? 196.777 172.219 172.584 1.00 59.72  ? 269 ILE A CD1 1 
ATOM   3681 N N   . ARG B  1 270 ? 202.009 170.684 173.221 1.00 54.03  ? 270 ARG A N   1 
ATOM   3682 C CA  . ARG B  1 270 ? 203.018 169.995 174.013 1.00 58.21  ? 270 ARG A CA  1 
ATOM   3683 C C   . ARG B  1 270 ? 203.888 170.972 174.793 1.00 63.77  ? 270 ARG A C   1 
ATOM   3684 O O   . ARG B  1 270 ? 204.369 170.635 175.880 1.00 72.77  ? 270 ARG A O   1 
ATOM   3685 C CB  . ARG B  1 270 ? 203.877 169.110 173.112 1.00 56.24  ? 270 ARG A CB  1 
ATOM   3686 C CG  . ARG B  1 270 ? 204.352 167.832 173.775 1.00 59.78  ? 270 ARG A CG  1 
ATOM   3687 C CD  . ARG B  1 270 ? 204.005 166.609 172.940 1.00 60.94  ? 270 ARG A CD  1 
ATOM   3688 N NE  . ARG B  1 270 ? 204.385 166.767 171.542 1.00 62.81  ? 270 ARG A NE  1 
ATOM   3689 C CZ  . ARG B  1 270 ? 203.640 166.379 170.516 1.00 65.32  ? 270 ARG A CZ  1 
ATOM   3690 N NH1 . ARG B  1 270 ? 202.467 165.797 170.696 1.00 68.49  ? 270 ARG A NH1 1 
ATOM   3691 N NH2 . ARG B  1 270 ? 204.085 166.577 169.279 1.00 65.10  ? 270 ARG A NH2 1 
ATOM   3692 N N   . ILE B  1 271 ? 204.111 172.174 174.260 1.00 54.71  ? 271 ILE A N   1 
ATOM   3693 C CA  . ILE B  1 271 ? 204.881 173.167 175.004 1.00 51.53  ? 271 ILE A CA  1 
ATOM   3694 C C   . ILE B  1 271 ? 204.085 173.682 176.197 1.00 58.16  ? 271 ILE A C   1 
ATOM   3695 O O   . ILE B  1 271 ? 204.624 173.828 177.301 1.00 56.54  ? 271 ILE A O   1 
ATOM   3696 C CB  . ILE B  1 271 ? 205.317 174.323 174.087 1.00 52.54  ? 271 ILE A CB  1 
ATOM   3697 C CG1 . ILE B  1 271 ? 206.170 173.809 172.928 1.00 57.06  ? 271 ILE A CG1 1 
ATOM   3698 C CG2 . ILE B  1 271 ? 206.078 175.367 174.881 1.00 54.68  ? 271 ILE A CG2 1 
ATOM   3699 C CD1 . ILE B  1 271 ? 207.552 173.399 173.315 1.00 62.75  ? 271 ILE A CD1 1 
ATOM   3700 N N   . TYR B  1 272 ? 202.797 173.968 176.003 1.00 61.65  ? 272 TYR A N   1 
ATOM   3701 C CA  . TYR B  1 272 ? 202.011 174.619 177.045 1.00 56.18  ? 272 TYR A CA  1 
ATOM   3702 C C   . TYR B  1 272 ? 201.340 173.650 178.011 1.00 55.61  ? 272 TYR A C   1 
ATOM   3703 O O   . TYR B  1 272 ? 200.806 174.095 179.037 1.00 58.84  ? 272 TYR A O   1 
ATOM   3704 C CB  . TYR B  1 272 ? 200.950 175.519 176.411 1.00 45.62  ? 272 TYR A CB  1 
ATOM   3705 C CG  . TYR B  1 272 ? 201.497 176.853 175.973 1.00 48.79  ? 272 TYR A CG  1 
ATOM   3706 C CD1 . TYR B  1 272 ? 201.881 177.806 176.904 1.00 51.90  ? 272 TYR A CD1 1 
ATOM   3707 C CD2 . TYR B  1 272 ? 201.648 177.154 174.630 1.00 52.98  ? 272 TYR A CD2 1 
ATOM   3708 C CE1 . TYR B  1 272 ? 202.387 179.021 176.509 1.00 54.50  ? 272 TYR A CE1 1 
ATOM   3709 C CE2 . TYR B  1 272 ? 202.154 178.368 174.227 1.00 49.35  ? 272 TYR A CE2 1 
ATOM   3710 C CZ  . TYR B  1 272 ? 202.521 179.297 175.170 1.00 46.69  ? 272 TYR A CZ  1 
ATOM   3711 O OH  . TYR B  1 272 ? 203.025 180.511 174.771 1.00 51.79  ? 272 TYR A OH  1 
ATOM   3712 N N   . ARG B  1 273 ? 201.356 172.347 177.722 1.00 52.35  ? 273 ARG A N   1 
ATOM   3713 C CA  . ARG B  1 273 ? 200.728 171.391 178.625 1.00 47.75  ? 273 ARG A CA  1 
ATOM   3714 C C   . ARG B  1 273 ? 201.442 171.347 179.966 1.00 47.82  ? 273 ARG A C   1 
ATOM   3715 O O   . ARG B  1 273 ? 200.799 171.217 181.012 1.00 57.69  ? 273 ARG A O   1 
ATOM   3716 C CB  . ARG B  1 273 ? 200.694 170.006 177.983 1.00 50.04  ? 273 ARG A CB  1 
ATOM   3717 C CG  . ARG B  1 273 ? 199.917 168.975 178.774 1.00 50.36  ? 273 ARG A CG  1 
ATOM   3718 C CD  . ARG B  1 273 ? 199.912 167.635 178.065 1.00 50.79  ? 273 ARG A CD  1 
ATOM   3719 N NE  . ARG B  1 273 ? 201.264 167.172 177.781 1.00 49.52  ? 273 ARG A NE  1 
ATOM   3720 C CZ  . ARG B  1 273 ? 201.612 166.496 176.696 1.00 56.87  ? 273 ARG A CZ  1 
ATOM   3721 N NH1 . ARG B  1 273 ? 200.727 166.182 175.765 1.00 58.84  ? 273 ARG A NH1 1 
ATOM   3722 N NH2 . ARG B  1 273 ? 202.880 166.127 176.539 1.00 55.97  ? 273 ARG A NH2 1 
ATOM   3723 N N   . GLY B  1 274 ? 202.772 171.449 179.961 1.00 36.88  ? 274 GLY A N   1 
ATOM   3724 C CA  . GLY B  1 274 ? 203.501 171.466 181.219 1.00 49.91  ? 274 GLY A CA  1 
ATOM   3725 C C   . GLY B  1 274 ? 203.135 172.656 182.084 1.00 48.48  ? 274 GLY A C   1 
ATOM   3726 O O   . GLY B  1 274 ? 202.914 172.517 183.292 1.00 53.55  ? 274 GLY A O   1 
ATOM   3727 N N   . GLY B  1 275 ? 203.054 173.840 181.477 1.00 44.62  ? 275 GLY A N   1 
ATOM   3728 C CA  . GLY B  1 275 ? 202.635 175.011 182.225 1.00 49.95  ? 275 GLY A CA  1 
ATOM   3729 C C   . GLY B  1 275 ? 201.227 174.878 182.770 1.00 46.82  ? 275 GLY A C   1 
ATOM   3730 O O   . GLY B  1 275 ? 200.967 175.211 183.929 1.00 56.04  ? 275 GLY A O   1 
ATOM   3731 N N   . PHE B  1 276 ? 200.301 174.377 181.947 1.00 42.59  ? 276 PHE A N   1 
ATOM   3732 C CA  . PHE B  1 276 ? 198.931 174.206 182.421 1.00 37.96  ? 276 PHE A CA  1 
ATOM   3733 C C   . PHE B  1 276 ? 198.866 173.215 183.573 1.00 41.90  ? 276 PHE A C   1 
ATOM   3734 O O   . PHE B  1 276 ? 198.121 173.421 184.539 1.00 55.40  ? 276 PHE A O   1 
ATOM   3735 C CB  . PHE B  1 276 ? 198.019 173.745 181.290 1.00 47.00  ? 276 PHE A CB  1 
ATOM   3736 C CG  . PHE B  1 276 ? 196.697 173.222 181.768 1.00 40.08  ? 276 PHE A CG  1 
ATOM   3737 C CD1 . PHE B  1 276 ? 195.797 174.061 182.400 1.00 45.50  ? 276 PHE A CD1 1 
ATOM   3738 C CD2 . PHE B  1 276 ? 196.362 171.891 181.603 1.00 39.87  ? 276 PHE A CD2 1 
ATOM   3739 C CE1 . PHE B  1 276 ? 194.585 173.585 182.850 1.00 50.61  ? 276 PHE A CE1 1 
ATOM   3740 C CE2 . PHE B  1 276 ? 195.152 171.409 182.052 1.00 46.58  ? 276 PHE A CE2 1 
ATOM   3741 C CZ  . PHE B  1 276 ? 194.262 172.256 182.675 1.00 52.22  ? 276 PHE A CZ  1 
ATOM   3742 N N   . LEU B  1 277 ? 199.629 172.124 183.483 1.00 44.54  ? 277 LEU A N   1 
ATOM   3743 C CA  . LEU B  1 277 ? 199.638 171.139 184.557 1.00 45.21  ? 277 LEU A CA  1 
ATOM   3744 C C   . LEU B  1 277 ? 200.218 171.726 185.832 1.00 48.94  ? 277 LEU A C   1 
ATOM   3745 O O   . LEU B  1 277 ? 199.751 171.415 186.931 1.00 44.67  ? 277 LEU A O   1 
ATOM   3746 C CB  . LEU B  1 277 ? 200.418 169.899 184.132 1.00 32.79  ? 277 LEU A CB  1 
ATOM   3747 C CG  . LEU B  1 277 ? 199.715 169.042 183.082 1.00 39.85  ? 277 LEU A CG  1 
ATOM   3748 C CD1 . LEU B  1 277 ? 200.724 168.238 182.300 1.00 43.57  ? 277 LEU A CD1 1 
ATOM   3749 C CD2 . LEU B  1 277 ? 198.691 168.139 183.727 1.00 51.34  ? 277 LEU A CD2 1 
ATOM   3750 N N   . LEU B  1 278 ? 201.236 172.579 185.711 1.00 49.87  ? 278 LEU A N   1 
ATOM   3751 C CA  . LEU B  1 278 ? 201.776 173.229 186.901 1.00 43.83  ? 278 LEU A CA  1 
ATOM   3752 C C   . LEU B  1 278 ? 200.748 174.163 187.533 1.00 40.22  ? 278 LEU A C   1 
ATOM   3753 O O   . LEU B  1 278 ? 200.607 174.199 188.763 1.00 46.22  ? 278 LEU A O   1 
ATOM   3754 C CB  . LEU B  1 278 ? 203.062 173.977 186.548 1.00 41.73  ? 278 LEU A CB  1 
ATOM   3755 C CG  . LEU B  1 278 ? 204.063 174.272 187.667 1.00 42.04  ? 278 LEU A CG  1 
ATOM   3756 C CD1 . LEU B  1 278 ? 205.408 174.592 187.060 1.00 51.66  ? 278 LEU A CD1 1 
ATOM   3757 C CD2 . LEU B  1 278 ? 203.615 175.422 188.550 1.00 43.74  ? 278 LEU A CD2 1 
ATOM   3758 N N   . ILE B  1 279 ? 200.015 174.920 186.711 1.00 37.52  ? 279 ILE A N   1 
ATOM   3759 C CA  . ILE B  1 279 ? 198.978 175.803 187.248 1.00 35.48  ? 279 ILE A CA  1 
ATOM   3760 C C   . ILE B  1 279 ? 197.918 174.987 187.974 1.00 39.74  ? 279 ILE A C   1 
ATOM   3761 O O   . ILE B  1 279 ? 197.495 175.324 189.089 1.00 55.24  ? 279 ILE A O   1 
ATOM   3762 C CB  . ILE B  1 279 ? 198.345 176.653 186.130 1.00 37.19  ? 279 ILE A CB  1 
ATOM   3763 C CG1 . ILE B  1 279 ? 199.408 177.368 185.300 1.00 38.47  ? 279 ILE A CG1 1 
ATOM   3764 C CG2 . ILE B  1 279 ? 197.368 177.654 186.718 1.00 34.44  ? 279 ILE A CG2 1 
ATOM   3765 C CD1 . ILE B  1 279 ? 200.464 178.042 186.106 1.00 44.41  ? 279 ILE A CD1 1 
ATOM   3766 N N   . GLU B  1 280 ? 197.468 173.901 187.342 1.00 35.54  ? 280 GLU A N   1 
ATOM   3767 C CA  . GLU B  1 280 ? 196.448 173.058 187.952 1.00 37.99  ? 280 GLU A CA  1 
ATOM   3768 C C   . GLU B  1 280 ? 196.955 172.429 189.241 1.00 46.85  ? 280 GLU A C   1 
ATOM   3769 O O   . GLU B  1 280 ? 196.210 172.318 190.218 1.00 47.16  ? 280 GLU A O   1 
ATOM   3770 C CB  . GLU B  1 280 ? 196.002 171.979 186.969 1.00 37.10  ? 280 GLU A CB  1 
ATOM   3771 C CG  . GLU B  1 280 ? 195.275 170.822 187.617 1.00 41.53  ? 280 GLU A CG  1 
ATOM   3772 C CD  . GLU B  1 280 ? 194.924 169.736 186.630 1.00 47.37  ? 280 GLU A CD  1 
ATOM   3773 O OE1 . GLU B  1 280 ? 195.306 169.861 185.449 1.00 45.34  ? 280 GLU A OE1 1 
ATOM   3774 O OE2 . GLU B  1 280 ? 194.262 168.760 187.034 1.00 52.87  ? 280 GLU A OE2 1 
ATOM   3775 N N   . PHE B  1 281 ? 198.221 172.007 189.262 1.00 43.51  ? 281 PHE A N   1 
ATOM   3776 C CA  . PHE B  1 281 ? 198.777 171.418 190.472 1.00 35.39  ? 281 PHE A CA  1 
ATOM   3777 C C   . PHE B  1 281 ? 198.822 172.430 191.604 1.00 39.28  ? 281 PHE A C   1 
ATOM   3778 O O   . PHE B  1 281 ? 198.493 172.101 192.745 1.00 46.55  ? 281 PHE A O   1 
ATOM   3779 C CB  . PHE B  1 281 ? 200.173 170.862 190.204 1.00 34.87  ? 281 PHE A CB  1 
ATOM   3780 C CG  . PHE B  1 281 ? 200.890 170.426 191.447 1.00 42.72  ? 281 PHE A CG  1 
ATOM   3781 C CD1 . PHE B  1 281 ? 200.409 169.372 192.203 1.00 43.46  ? 281 PHE A CD1 1 
ATOM   3782 C CD2 . PHE B  1 281 ? 202.035 171.076 191.867 1.00 42.92  ? 281 PHE A CD2 1 
ATOM   3783 C CE1 . PHE B  1 281 ? 201.060 168.972 193.348 1.00 45.55  ? 281 PHE A CE1 1 
ATOM   3784 C CE2 . PHE B  1 281 ? 202.689 170.680 193.013 1.00 41.52  ? 281 PHE A CE2 1 
ATOM   3785 C CZ  . PHE B  1 281 ? 202.202 169.628 193.754 1.00 43.13  ? 281 PHE A CZ  1 
ATOM   3786 N N   . LEU B  1 282 ? 199.225 173.669 191.312 1.00 38.83  ? 282 LEU A N   1 
ATOM   3787 C CA  . LEU B  1 282 ? 199.259 174.688 192.359 1.00 28.92  ? 282 LEU A CA  1 
ATOM   3788 C C   . LEU B  1 282 ? 197.857 175.002 192.877 1.00 33.53  ? 282 LEU A C   1 
ATOM   3789 O O   . LEU B  1 282 ? 197.653 175.150 194.088 1.00 46.55  ? 282 LEU A O   1 
ATOM   3790 C CB  . LEU B  1 282 ? 199.941 175.951 191.840 1.00 31.12  ? 282 LEU A CB  1 
ATOM   3791 C CG  . LEU B  1 282 ? 201.404 176.154 192.239 1.00 27.99  ? 282 LEU A CG  1 
ATOM   3792 C CD1 . LEU B  1 282 ? 201.502 176.529 193.701 1.00 36.07  ? 282 LEU A CD1 1 
ATOM   3793 C CD2 . LEU B  1 282 ? 202.226 174.912 191.956 1.00 30.23  ? 282 LEU A CD2 1 
ATOM   3794 N N   . PHE B  1 283 ? 196.878 175.097 191.977 1.00 31.28  ? 283 PHE A N   1 
ATOM   3795 C CA  . PHE B  1 283 ? 195.506 175.380 192.396 1.00 24.96  ? 283 PHE A CA  1 
ATOM   3796 C C   . PHE B  1 283 ? 194.943 174.240 193.246 1.00 34.91  ? 283 PHE A C   1 
ATOM   3797 O O   . PHE B  1 283 ? 194.359 174.467 194.317 1.00 41.10  ? 283 PHE A O   1 
ATOM   3798 C CB  . PHE B  1 283 ? 194.655 175.642 191.150 1.00 27.95  ? 283 PHE A CB  1 
ATOM   3799 C CG  . PHE B  1 283 ? 193.187 175.398 191.333 1.00 34.28  ? 283 PHE A CG  1 
ATOM   3800 C CD1 . PHE B  1 283 ? 192.454 176.127 192.251 1.00 39.45  ? 283 PHE A CD1 1 
ATOM   3801 C CD2 . PHE B  1 283 ? 192.531 174.461 190.554 1.00 42.44  ? 283 PHE A CD2 1 
ATOM   3802 C CE1 . PHE B  1 283 ? 191.102 175.908 192.408 1.00 38.10  ? 283 PHE A CE1 1 
ATOM   3803 C CE2 . PHE B  1 283 ? 191.179 174.239 190.704 1.00 42.01  ? 283 PHE A CE2 1 
ATOM   3804 C CZ  . PHE B  1 283 ? 190.463 174.965 191.630 1.00 42.52  ? 283 PHE A CZ  1 
ATOM   3805 N N   . LEU B  1 284 ? 195.137 172.998 192.798 1.00 37.93  ? 284 LEU A N   1 
ATOM   3806 C CA  . LEU B  1 284 ? 194.669 171.849 193.562 1.00 32.44  ? 284 LEU A CA  1 
ATOM   3807 C C   . LEU B  1 284 ? 195.431 171.699 194.871 1.00 41.84  ? 284 LEU A C   1 
ATOM   3808 O O   . LEU B  1 284 ? 194.882 171.187 195.848 1.00 43.04  ? 284 LEU A O   1 
ATOM   3809 C CB  . LEU B  1 284 ? 194.786 170.580 192.720 1.00 16.84  ? 284 LEU A CB  1 
ATOM   3810 C CG  . LEU B  1 284 ? 193.874 170.517 191.494 1.00 24.63  ? 284 LEU A CG  1 
ATOM   3811 C CD1 . LEU B  1 284 ? 193.855 169.125 190.902 1.00 22.82  ? 284 LEU A CD1 1 
ATOM   3812 C CD2 . LEU B  1 284 ? 192.469 170.960 191.849 1.00 43.67  ? 284 LEU A CD2 1 
ATOM   3813 N N   . LEU B  1 285 ? 196.685 172.151 194.921 1.00 45.53  ? 285 LEU A N   1 
ATOM   3814 C CA  . LEU B  1 285 ? 197.430 172.134 196.173 1.00 38.15  ? 285 LEU A CA  1 
ATOM   3815 C C   . LEU B  1 285 ? 196.905 173.178 197.146 1.00 41.66  ? 285 LEU A C   1 
ATOM   3816 O O   . LEU B  1 285 ? 196.910 172.950 198.360 1.00 51.69  ? 285 LEU A O   1 
ATOM   3817 C CB  . LEU B  1 285 ? 198.913 172.356 195.896 1.00 30.81  ? 285 LEU A CB  1 
ATOM   3818 C CG  . LEU B  1 285 ? 199.875 172.066 197.043 1.00 35.85  ? 285 LEU A CG  1 
ATOM   3819 C CD1 . LEU B  1 285 ? 199.538 170.744 197.702 1.00 40.89  ? 285 LEU A CD1 1 
ATOM   3820 C CD2 . LEU B  1 285 ? 201.286 172.048 196.513 1.00 36.11  ? 285 LEU A CD2 1 
ATOM   3821 N N   . GLY B  1 286 ? 196.459 174.327 196.641 1.00 35.22  ? 286 GLY A N   1 
ATOM   3822 C CA  . GLY B  1 286 ? 195.744 175.258 197.498 1.00 34.95  ? 286 GLY A CA  1 
ATOM   3823 C C   . GLY B  1 286 ? 194.471 174.651 198.057 1.00 42.80  ? 286 GLY A C   1 
ATOM   3824 O O   . GLY B  1 286 ? 194.164 174.801 199.246 1.00 57.55  ? 286 GLY A O   1 
ATOM   3825 N N   . ILE B  1 287 ? 193.719 173.945 197.209 1.00 35.49  ? 287 ILE A N   1 
ATOM   3826 C CA  . ILE B  1 287 ? 192.538 173.230 197.695 1.00 25.59  ? 287 ILE A CA  1 
ATOM   3827 C C   . ILE B  1 287 ? 192.931 172.222 198.768 1.00 43.92  ? 287 ILE A C   1 
ATOM   3828 O O   . ILE B  1 287 ? 192.243 172.070 199.785 1.00 48.45  ? 287 ILE A O   1 
ATOM   3829 C CB  . ILE B  1 287 ? 191.798 172.543 196.533 1.00 27.30  ? 287 ILE A CB  1 
ATOM   3830 C CG1 . ILE B  1 287 ? 191.222 173.573 195.566 1.00 40.52  ? 287 ILE A CG1 1 
ATOM   3831 C CG2 . ILE B  1 287 ? 190.683 171.661 197.062 1.00 30.85  ? 287 ILE A CG2 1 
ATOM   3832 C CD1 . ILE B  1 287 ? 190.469 172.948 194.418 1.00 37.41  ? 287 ILE A CD1 1 
ATOM   3833 N N   . ASN B  1 288 ? 194.040 171.511 198.552 1.00 47.91  ? 288 ASN A N   1 
ATOM   3834 C CA  . ASN B  1 288 ? 194.510 170.528 199.522 1.00 34.00  ? 288 ASN A CA  1 
ATOM   3835 C C   . ASN B  1 288 ? 194.864 171.183 200.847 1.00 44.12  ? 288 ASN A C   1 
ATOM   3836 O O   . ASN B  1 288 ? 194.569 170.635 201.912 1.00 52.04  ? 288 ASN A O   1 
ATOM   3837 C CB  . ASN B  1 288 ? 195.724 169.781 198.972 1.00 22.21  ? 288 ASN A CB  1 
ATOM   3838 C CG  . ASN B  1 288 ? 195.343 168.587 198.137 1.00 31.18  ? 288 ASN A CG  1 
ATOM   3839 O OD1 . ASN B  1 288 ? 195.922 168.346 197.081 1.00 40.97  ? 288 ASN A OD1 1 
ATOM   3840 N ND2 . ASN B  1 288 ? 194.362 167.831 198.603 1.00 43.62  ? 288 ASN A ND2 1 
ATOM   3841 N N   . THR B  1 289 ? 195.528 172.337 200.802 1.00 43.05  ? 289 THR A N   1 
ATOM   3842 C CA  . THR B  1 289 ? 195.880 173.034 202.034 1.00 38.02  ? 289 THR A CA  1 
ATOM   3843 C C   . THR B  1 289 ? 194.632 173.473 202.787 1.00 38.22  ? 289 THR A C   1 
ATOM   3844 O O   . THR B  1 289 ? 194.563 173.350 204.017 1.00 46.61  ? 289 THR A O   1 
ATOM   3845 C CB  . THR B  1 289 ? 196.771 174.234 201.725 1.00 39.86  ? 289 THR A CB  1 
ATOM   3846 O OG1 . THR B  1 289 ? 197.955 173.788 201.057 1.00 55.82  ? 289 THR A OG1 1 
ATOM   3847 C CG2 . THR B  1 289 ? 197.165 174.943 203.007 1.00 45.91  ? 289 THR A CG2 1 
ATOM   3848 N N   . TYR B  1 290 ? 193.630 173.982 202.066 1.00 42.71  ? 290 TYR A N   1 
ATOM   3849 C CA  . TYR B  1 290 ? 192.372 174.344 202.715 1.00 47.26  ? 290 TYR A CA  1 
ATOM   3850 C C   . TYR B  1 290 ? 191.722 173.127 203.361 1.00 46.92  ? 290 TYR A C   1 
ATOM   3851 O O   . TYR B  1 290 ? 191.236 173.193 204.499 1.00 50.60  ? 290 TYR A O   1 
ATOM   3852 C CB  . TYR B  1 290 ? 191.423 174.986 201.704 1.00 53.87  ? 290 TYR A CB  1 
ATOM   3853 C CG  . TYR B  1 290 ? 189.960 174.816 202.051 1.00 51.68  ? 290 TYR A CG  1 
ATOM   3854 C CD1 . TYR B  1 290 ? 189.342 175.652 202.969 1.00 48.74  ? 290 TYR A CD1 1 
ATOM   3855 C CD2 . TYR B  1 290 ? 189.195 173.822 201.454 1.00 55.88  ? 290 TYR A CD2 1 
ATOM   3856 C CE1 . TYR B  1 290 ? 188.009 175.499 203.287 1.00 54.21  ? 290 TYR A CE1 1 
ATOM   3857 C CE2 . TYR B  1 290 ? 187.862 173.663 201.768 1.00 55.77  ? 290 TYR A CE2 1 
ATOM   3858 C CZ  . TYR B  1 290 ? 187.274 174.504 202.685 1.00 58.55  ? 290 TYR A CZ  1 
ATOM   3859 O OH  . TYR B  1 290 ? 185.944 174.349 202.999 1.00 60.06  ? 290 TYR A OH  1 
ATOM   3860 N N   . GLY B  1 291 ? 191.697 172.006 202.640 1.00 42.12  ? 291 GLY A N   1 
ATOM   3861 C CA  . GLY B  1 291 ? 191.106 170.797 203.186 1.00 43.57  ? 291 GLY A CA  1 
ATOM   3862 C C   . GLY B  1 291 ? 191.844 170.291 204.409 1.00 47.59  ? 291 GLY A C   1 
ATOM   3863 O O   . GLY B  1 291 ? 191.228 169.842 205.375 1.00 54.33  ? 291 GLY A O   1 
ATOM   3864 N N   . TRP B  1 292 ? 193.176 170.354 204.380 1.00 41.78  ? 292 TRP A N   1 
ATOM   3865 C CA  . TRP B  1 292 ? 193.959 169.948 205.539 1.00 42.27  ? 292 TRP A CA  1 
ATOM   3866 C C   . TRP B  1 292 ? 193.678 170.844 206.734 1.00 50.79  ? 292 TRP A C   1 
ATOM   3867 O O   . TRP B  1 292 ? 193.532 170.359 207.862 1.00 52.83  ? 292 TRP A O   1 
ATOM   3868 C CB  . TRP B  1 292 ? 195.452 169.966 205.212 1.00 45.60  ? 292 TRP A CB  1 
ATOM   3869 C CG  . TRP B  1 292 ? 195.858 169.019 204.137 1.00 41.46  ? 292 TRP A CG  1 
ATOM   3870 C CD1 . TRP B  1 292 ? 195.230 167.867 203.781 1.00 42.08  ? 292 TRP A CD1 1 
ATOM   3871 C CD2 . TRP B  1 292 ? 196.997 169.139 203.279 1.00 35.95  ? 292 TRP A CD2 1 
ATOM   3872 N NE1 . TRP B  1 292 ? 195.903 167.262 202.749 1.00 43.03  ? 292 TRP A NE1 1 
ATOM   3873 C CE2 . TRP B  1 292 ? 196.992 168.025 202.422 1.00 42.56  ? 292 TRP A CE2 1 
ATOM   3874 C CE3 . TRP B  1 292 ? 198.017 170.083 203.150 1.00 42.72  ? 292 TRP A CE3 1 
ATOM   3875 C CZ2 . TRP B  1 292 ? 197.967 167.829 201.451 1.00 52.44  ? 292 TRP A CZ2 1 
ATOM   3876 C CZ3 . TRP B  1 292 ? 198.984 169.887 202.187 1.00 50.43  ? 292 TRP A CZ3 1 
ATOM   3877 C CH2 . TRP B  1 292 ? 198.953 168.770 201.350 1.00 52.60  ? 292 TRP A CH2 1 
ATOM   3878 N N   . ARG B  1 293 ? 193.604 172.156 206.509 1.00 62.22  ? 293 ARG A N   1 
ATOM   3879 C CA  . ARG B  1 293 ? 193.367 173.070 207.619 1.00 58.69  ? 293 ARG A CA  1 
ATOM   3880 C C   . ARG B  1 293 ? 191.991 172.856 208.235 1.00 61.00  ? 293 ARG A C   1 
ATOM   3881 O O   . ARG B  1 293 ? 191.855 172.828 209.463 1.00 67.00  ? 293 ARG A O   1 
ATOM   3882 C CB  . ARG B  1 293 ? 193.533 174.515 207.154 1.00 60.92  ? 293 ARG A CB  1 
ATOM   3883 C CG  . ARG B  1 293 ? 193.636 175.508 208.291 1.00 63.69  ? 293 ARG A CG  1 
ATOM   3884 C CD  . ARG B  1 293 ? 194.257 176.814 207.820 1.00 64.75  ? 293 ARG A CD  1 
ATOM   3885 N NE  . ARG B  1 293 ? 195.712 176.757 207.707 1.00 68.76  ? 293 ARG A NE  1 
ATOM   3886 C CZ  . ARG B  1 293 ? 196.550 176.312 208.638 1.00 70.49  ? 293 ARG A CZ  1 
ATOM   3887 N NH1 . ARG B  1 293 ? 196.136 175.970 209.848 1.00 68.74  ? 293 ARG A NH1 1 
ATOM   3888 N NH2 . ARG B  1 293 ? 197.846 176.231 208.354 1.00 69.80  ? 293 ARG A NH2 1 
ATOM   3889 N N   . GLN B  1 294 ? 190.959 172.695 207.405 1.00 53.34  ? 294 GLN A N   1 
ATOM   3890 C CA  . GLN B  1 294 ? 189.610 172.573 207.950 1.00 53.81  ? 294 GLN A CA  1 
ATOM   3891 C C   . GLN B  1 294 ? 189.356 171.188 208.534 1.00 56.41  ? 294 GLN A C   1 
ATOM   3892 O O   . GLN B  1 294 ? 188.657 171.056 209.546 1.00 59.58  ? 294 GLN A O   1 
ATOM   3893 C CB  . GLN B  1 294 ? 188.575 172.905 206.878 1.00 49.26  ? 294 GLN A CB  1 
ATOM   3894 C CG  . GLN B  1 294 ? 188.601 174.355 206.433 1.00 57.35  ? 294 GLN A CG  1 
ATOM   3895 C CD  . GLN B  1 294 ? 188.578 175.335 207.593 1.00 64.63  ? 294 GLN A CD  1 
ATOM   3896 O OE1 . GLN B  1 294 ? 187.892 175.120 208.593 1.00 66.38  ? 294 GLN A OE1 1 
ATOM   3897 N NE2 . GLN B  1 294 ? 189.332 176.420 207.464 1.00 58.92  ? 294 GLN A NE2 1 
ATOM   3898 N N   . ALA B  1 295 ? 189.903 170.143 207.911 1.00 55.45  ? 295 ALA A N   1 
ATOM   3899 C CA  . ALA B  1 295 ? 189.637 168.783 208.367 1.00 56.20  ? 295 ALA A CA  1 
ATOM   3900 C C   . ALA B  1 295 ? 190.234 168.524 209.744 1.00 60.44  ? 295 ALA A C   1 
ATOM   3901 O O   . ALA B  1 295 ? 189.596 167.892 210.593 1.00 64.25  ? 295 ALA A O   1 
ATOM   3902 C CB  . ALA B  1 295 ? 190.178 167.780 207.353 1.00 54.20  ? 295 ALA A CB  1 
ATOM   3903 N N   . GLY B  1 296 ? 191.453 168.997 209.983 1.00 54.78  ? 296 GLY A N   1 
ATOM   3904 C CA  . GLY B  1 296 ? 192.103 168.773 211.258 1.00 55.06  ? 296 GLY A CA  1 
ATOM   3905 C C   . GLY B  1 296 ? 193.508 168.226 211.130 1.00 61.40  ? 296 GLY A C   1 
ATOM   3906 O O   . GLY B  1 296 ? 194.310 168.344 212.060 1.00 67.57  ? 296 GLY A O   1 
ATOM   3907 N N   . VAL B  1 297 ? 193.818 167.619 209.984 1.00 59.38  ? 297 VAL A N   1 
ATOM   3908 C CA  . VAL B  1 297 ? 195.169 167.123 209.742 1.00 55.49  ? 297 VAL A CA  1 
ATOM   3909 C C   . VAL B  1 297 ? 196.145 168.291 209.740 1.00 58.50  ? 297 VAL A C   1 
ATOM   3910 O O   . VAL B  1 297 ? 195.969 169.273 209.008 1.00 60.75  ? 297 VAL A O   1 
ATOM   3911 C CB  . VAL B  1 297 ? 195.223 166.312 208.443 1.00 53.02  ? 297 VAL A CB  1 
ATOM   3912 C CG1 . VAL B  1 297 ? 194.619 167.082 207.309 1.00 59.18  ? 297 VAL A CG1 1 
ATOM   3913 C CG2 . VAL B  1 297 ? 196.660 165.999 208.088 1.00 55.77  ? 297 VAL A CG2 1 
ATOM   3914 N N   . ASN B  1 298 ? 197.175 168.195 210.580 1.00 57.02  ? 298 ASN A N   1 
ATOM   3915 C CA  . ASN B  1 298 ? 198.149 169.270 210.763 1.00 54.32  ? 298 ASN A CA  1 
ATOM   3916 C C   . ASN B  1 298 ? 199.286 169.058 209.776 1.00 49.14  ? 298 ASN A C   1 
ATOM   3917 O O   . ASN B  1 298 ? 200.238 168.324 210.038 1.00 55.78  ? 298 ASN A O   1 
ATOM   3918 C CB  . ASN B  1 298 ? 198.652 169.295 212.201 1.00 53.98  ? 298 ASN A CB  1 
ATOM   3919 C CG  . ASN B  1 298 ? 199.519 170.502 212.495 1.00 59.84  ? 298 ASN A CG  1 
ATOM   3920 O OD1 . ASN B  1 298 ? 199.743 171.348 211.630 1.00 65.58  ? 298 ASN A OD1 1 
ATOM   3921 N ND2 . ASN B  1 298 ? 200.015 170.587 213.724 1.00 59.25  ? 298 ASN A ND2 1 
ATOM   3922 N N   . HIS B  1 299 ? 199.190 169.717 208.621 1.00 48.72  ? 299 HIS A N   1 
ATOM   3923 C CA  . HIS B  1 299 ? 200.245 169.606 207.623 1.00 49.97  ? 299 HIS A CA  1 
ATOM   3924 C C   . HIS B  1 299 ? 201.489 170.394 208.005 1.00 57.71  ? 299 HIS A C   1 
ATOM   3925 O O   . HIS B  1 299 ? 202.577 170.081 207.512 1.00 63.90  ? 299 HIS A O   1 
ATOM   3926 C CB  . HIS B  1 299 ? 199.735 170.071 206.260 1.00 45.81  ? 299 HIS A CB  1 
ATOM   3927 C CG  . HIS B  1 299 ? 199.539 171.551 206.162 1.00 51.83  ? 299 HIS A CG  1 
ATOM   3928 N ND1 . HIS B  1 299 ? 200.282 172.344 205.316 1.00 56.39  ? 299 HIS A ND1 1 
ATOM   3929 C CD2 . HIS B  1 299 ? 198.682 172.381 206.801 1.00 59.91  ? 299 HIS A CD2 1 
ATOM   3930 C CE1 . HIS B  1 299 ? 199.893 173.600 205.439 1.00 54.88  ? 299 HIS A CE1 1 
ATOM   3931 N NE2 . HIS B  1 299 ? 198.923 173.650 206.334 1.00 61.38  ? 299 HIS A NE2 1 
ATOM   3932 N N   . VAL B  1 300 ? 201.358 171.404 208.865 1.00 59.52  ? 300 VAL A N   1 
ATOM   3933 C CA  . VAL B  1 300 ? 202.520 172.192 209.267 1.00 55.22  ? 300 VAL A CA  1 
ATOM   3934 C C   . VAL B  1 300 ? 203.488 171.339 210.076 1.00 54.88  ? 300 VAL A C   1 
ATOM   3935 O O   . VAL B  1 300 ? 204.697 171.326 209.816 1.00 60.37  ? 300 VAL A O   1 
ATOM   3936 C CB  . VAL B  1 300 ? 202.076 173.440 210.050 1.00 54.69  ? 300 VAL A CB  1 
ATOM   3937 C CG1 . VAL B  1 300 ? 203.220 173.972 210.896 1.00 56.22  ? 300 VAL A CG1 1 
ATOM   3938 C CG2 . VAL B  1 300 ? 201.576 174.509 209.097 1.00 58.36  ? 300 VAL A CG2 1 
ATOM   3939 N N   . LEU B  1 301 ? 202.973 170.613 211.070 1.00 50.91  ? 301 LEU A N   1 
ATOM   3940 C CA  . LEU B  1 301 ? 203.826 169.731 211.860 1.00 56.55  ? 301 LEU A CA  1 
ATOM   3941 C C   . LEU B  1 301 ? 204.380 168.592 211.014 1.00 53.02  ? 301 LEU A C   1 
ATOM   3942 O O   . LEU B  1 301 ? 205.554 168.227 211.146 1.00 53.38  ? 301 LEU A O   1 
ATOM   3943 C CB  . LEU B  1 301 ? 203.048 169.182 213.054 1.00 54.48  ? 301 LEU A CB  1 
ATOM   3944 C CG  . LEU B  1 301 ? 203.607 167.912 213.696 1.00 54.44  ? 301 LEU A CG  1 
ATOM   3945 C CD1 . LEU B  1 301 ? 204.835 168.228 214.533 1.00 50.76  ? 301 LEU A CD1 1 
ATOM   3946 C CD2 . LEU B  1 301 ? 202.543 167.224 214.535 1.00 55.64  ? 301 LEU A CD2 1 
ATOM   3947 N N   . ILE B  1 302 ? 203.549 168.018 210.143 1.00 51.90  ? 302 ILE A N   1 
ATOM   3948 C CA  . ILE B  1 302 ? 203.985 166.892 209.322 1.00 41.82  ? 302 ILE A CA  1 
ATOM   3949 C C   . ILE B  1 302 ? 205.099 167.323 208.377 1.00 44.77  ? 302 ILE A C   1 
ATOM   3950 O O   . ILE B  1 302 ? 206.123 166.643 208.244 1.00 60.87  ? 302 ILE A O   1 
ATOM   3951 C CB  . ILE B  1 302 ? 202.789 166.296 208.559 1.00 38.99  ? 302 ILE A CB  1 
ATOM   3952 C CG1 . ILE B  1 302 ? 201.840 165.599 209.529 1.00 47.52  ? 302 ILE A CG1 1 
ATOM   3953 C CG2 . ILE B  1 302 ? 203.258 165.308 207.523 1.00 47.69  ? 302 ILE A CG2 1 
ATOM   3954 C CD1 . ILE B  1 302 ? 200.587 165.079 208.877 1.00 48.20  ? 302 ILE A CD1 1 
ATOM   3955 N N   . PHE B  1 303 ? 204.922 168.465 207.714 1.00 33.21  ? 303 PHE A N   1 
ATOM   3956 C CA  . PHE B  1 303 ? 205.941 168.987 206.813 1.00 45.79  ? 303 PHE A CA  1 
ATOM   3957 C C   . PHE B  1 303 ? 207.137 169.583 207.541 1.00 56.22  ? 303 PHE A C   1 
ATOM   3958 O O   . PHE B  1 303 ? 208.135 169.905 206.887 1.00 57.86  ? 303 PHE A O   1 
ATOM   3959 C CB  . PHE B  1 303 ? 205.342 170.050 205.892 1.00 41.79  ? 303 PHE A CB  1 
ATOM   3960 C CG  . PHE B  1 303 ? 204.677 169.495 204.671 1.00 41.47  ? 303 PHE A CG  1 
ATOM   3961 C CD1 . PHE B  1 303 ? 203.430 168.910 204.752 1.00 48.12  ? 303 PHE A CD1 1 
ATOM   3962 C CD2 . PHE B  1 303 ? 205.296 169.572 203.440 1.00 39.71  ? 303 PHE A CD2 1 
ATOM   3963 C CE1 . PHE B  1 303 ? 202.816 168.407 203.631 1.00 44.94  ? 303 PHE A CE1 1 
ATOM   3964 C CE2 . PHE B  1 303 ? 204.686 169.070 202.318 1.00 42.99  ? 303 PHE A CE2 1 
ATOM   3965 C CZ  . PHE B  1 303 ? 203.445 168.486 202.414 1.00 43.17  ? 303 PHE A CZ  1 
ATOM   3966 N N   . GLU B  1 304 ? 207.057 169.745 208.864 1.00 63.50  ? 304 GLU A N   1 
ATOM   3967 C CA  . GLU B  1 304 ? 208.109 170.386 209.655 1.00 64.16  ? 304 GLU A CA  1 
ATOM   3968 C C   . GLU B  1 304 ? 208.356 171.816 209.176 1.00 69.13  ? 304 GLU A C   1 
ATOM   3969 O O   . GLU B  1 304 ? 209.455 172.176 208.749 1.00 67.70  ? 304 GLU A O   1 
ATOM   3970 C CB  . GLU B  1 304 ? 209.400 169.564 209.634 1.00 57.53  ? 304 GLU A CB  1 
ATOM   3971 C CG  . GLU B  1 304 ? 209.246 168.155 210.179 1.00 60.49  ? 304 GLU A CG  1 
ATOM   3972 C CD  . GLU B  1 304 ? 209.772 167.101 209.226 1.00 68.39  ? 304 GLU A CD  1 
ATOM   3973 O OE1 . GLU B  1 304 ? 210.419 167.475 208.225 1.00 66.02  ? 304 GLU A OE1 1 
ATOM   3974 O OE2 . GLU B  1 304 ? 209.538 165.900 209.477 1.00 66.61  ? 304 GLU A OE2 1 
ATOM   3975 N N   . LEU B  1 305 ? 207.313 172.635 209.248 1.00 72.34  ? 305 LEU A N   1 
ATOM   3976 C CA  . LEU B  1 305 ? 207.367 174.029 208.836 1.00 72.13  ? 305 LEU A CA  1 
ATOM   3977 C C   . LEU B  1 305 ? 207.247 174.948 210.045 1.00 71.72  ? 305 LEU A C   1 
ATOM   3978 O O   . LEU B  1 305 ? 206.690 174.582 211.083 1.00 69.04  ? 305 LEU A O   1 
ATOM   3979 C CB  . LEU B  1 305 ? 206.252 174.346 207.837 1.00 68.99  ? 305 LEU A CB  1 
ATOM   3980 C CG  . LEU B  1 305 ? 206.203 173.519 206.554 1.00 66.56  ? 305 LEU A CG  1 
ATOM   3981 C CD1 . LEU B  1 305 ? 205.057 173.981 205.673 1.00 63.83  ? 305 LEU A CD1 1 
ATOM   3982 C CD2 . LEU B  1 305 ? 207.522 173.608 205.813 1.00 62.80  ? 305 LEU A CD2 1 
ATOM   3983 N N   . ASN B  1 306 ? 207.777 176.153 209.896 1.00 85.41  ? 306 ASN A N   1 
ATOM   3984 C CA  . ASN B  1 306 ? 207.639 177.160 210.939 1.00 82.63  ? 306 ASN A CA  1 
ATOM   3985 C C   . ASN B  1 306 ? 206.201 177.661 210.961 1.00 88.14  ? 306 ASN A C   1 
ATOM   3986 O O   . ASN B  1 306 ? 205.710 178.148 209.934 1.00 91.06  ? 306 ASN A O   1 
ATOM   3987 C CB  . ASN B  1 306 ? 208.607 178.315 210.701 1.00 86.39  ? 306 ASN A CB  1 
ATOM   3988 C CG  . ASN B  1 306 ? 210.059 177.881 210.771 1.00 86.66  ? 306 ASN A CG  1 
ATOM   3989 O OD1 . ASN B  1 306 ? 210.359 176.715 211.026 1.00 85.34  ? 306 ASN A OD1 1 
ATOM   3990 N ND2 . ASN B  1 306 ? 210.969 178.821 210.545 1.00 87.25  ? 306 ASN A ND2 1 
ATOM   3991 N N   . PRO B  1 307 ? 205.493 177.559 212.087 1.00 96.00  ? 307 PRO A N   1 
ATOM   3992 C CA  . PRO B  1 307 ? 204.071 177.944 212.101 1.00 96.93  ? 307 PRO A CA  1 
ATOM   3993 C C   . PRO B  1 307 ? 203.824 179.416 211.822 1.00 95.30  ? 307 PRO A C   1 
ATOM   3994 O O   . PRO B  1 307 ? 202.691 179.783 211.486 1.00 93.79  ? 307 PRO A O   1 
ATOM   3995 C CB  . PRO B  1 307 ? 203.618 177.563 213.518 1.00 94.47  ? 307 PRO A CB  1 
ATOM   3996 C CG  . PRO B  1 307 ? 204.625 176.559 213.988 1.00 92.02  ? 307 PRO A CG  1 
ATOM   3997 C CD  . PRO B  1 307 ? 205.921 176.972 213.366 1.00 90.74  ? 307 PRO A CD  1 
ATOM   3998 N N   . ARG B  1 308 ? 204.837 180.273 211.956 1.00 101.26 ? 308 ARG A N   1 
ATOM   3999 C CA  . ARG B  1 308 ? 204.621 181.706 211.778 1.00 101.63 ? 308 ARG A CA  1 
ATOM   4000 C C   . ARG B  1 308 ? 204.404 182.062 210.312 1.00 100.69 ? 308 ARG A C   1 
ATOM   4001 O O   . ARG B  1 308 ? 203.497 182.833 209.980 1.00 103.12 ? 308 ARG A O   1 
ATOM   4002 C CB  . ARG B  1 308 ? 205.803 182.487 212.352 1.00 106.19 ? 308 ARG A CB  1 
ATOM   4003 C CG  . ARG B  1 308 ? 206.242 182.029 213.732 1.00 103.39 ? 308 ARG A CG  1 
ATOM   4004 C CD  . ARG B  1 308 ? 205.141 182.242 214.758 1.00 105.09 ? 308 ARG A CD  1 
ATOM   4005 N NE  . ARG B  1 308 ? 205.649 182.183 216.123 1.00 104.68 ? 308 ARG A NE  1 
ATOM   4006 C CZ  . ARG B  1 308 ? 206.199 183.207 216.761 1.00 104.78 ? 308 ARG A CZ  1 
ATOM   4007 N NH1 . ARG B  1 308 ? 206.327 184.391 216.185 1.00 104.19 ? 308 ARG A NH1 1 
ATOM   4008 N NH2 . ARG B  1 308 ? 206.630 183.039 218.007 1.00 103.54 ? 308 ARG A NH2 1 
ATOM   4009 N N   . SER B  1 309 ? 205.225 181.512 209.419 1.00 85.33  ? 309 SER A N   1 
ATOM   4010 C CA  . SER B  1 309 ? 205.216 181.902 208.016 1.00 89.07  ? 309 SER A CA  1 
ATOM   4011 C C   . SER B  1 309 ? 204.650 180.828 207.096 1.00 88.53  ? 309 SER A C   1 
ATOM   4012 O O   . SER B  1 309 ? 204.939 180.844 205.895 1.00 88.45  ? 309 SER A O   1 
ATOM   4013 C CB  . SER B  1 309 ? 206.630 182.275 207.566 1.00 86.59  ? 309 SER A CB  1 
ATOM   4014 O OG  . SER B  1 309 ? 206.638 182.683 206.209 1.00 84.22  ? 309 SER A OG  1 
ATOM   4015 N N   . ASN B  1 310 ? 203.860 179.898 207.625 1.00 86.68  ? 310 ASN A N   1 
ATOM   4016 C CA  . ASN B  1 310 ? 203.256 178.873 206.784 1.00 86.06  ? 310 ASN A CA  1 
ATOM   4017 C C   . ASN B  1 310 ? 202.263 179.496 205.810 1.00 86.63  ? 310 ASN A C   1 
ATOM   4018 O O   . ASN B  1 310 ? 201.553 180.449 206.144 1.00 89.43  ? 310 ASN A O   1 
ATOM   4019 C CB  . ASN B  1 310 ? 202.565 177.822 207.652 1.00 86.15  ? 310 ASN A CB  1 
ATOM   4020 C CG  . ASN B  1 310 ? 201.406 178.392 208.437 1.00 86.02  ? 310 ASN A CG  1 
ATOM   4021 O OD1 . ASN B  1 310 ? 201.449 179.535 208.890 1.00 90.97  ? 310 ASN A OD1 1 
ATOM   4022 N ND2 . ASN B  1 310 ? 200.361 177.596 208.608 1.00 84.78  ? 310 ASN A ND2 1 
ATOM   4023 N N   . LEU B  1 311 ? 202.220 178.955 204.596 1.00 76.68  ? 311 LEU A N   1 
ATOM   4024 C CA  . LEU B  1 311 ? 201.362 179.493 203.548 1.00 77.33  ? 311 LEU A CA  1 
ATOM   4025 C C   . LEU B  1 311 ? 199.940 178.977 203.721 1.00 81.08  ? 311 LEU A C   1 
ATOM   4026 O O   . LEU B  1 311 ? 199.713 177.762 203.754 1.00 84.54  ? 311 LEU A O   1 
ATOM   4027 C CB  . LEU B  1 311 ? 201.895 179.113 202.169 1.00 72.13  ? 311 LEU A CB  1 
ATOM   4028 C CG  . LEU B  1 311 ? 202.956 180.021 201.553 1.00 79.17  ? 311 LEU A CG  1 
ATOM   4029 C CD1 . LEU B  1 311 ? 202.971 179.868 200.040 1.00 76.73  ? 311 LEU A CD1 1 
ATOM   4030 C CD2 . LEU B  1 311 ? 202.730 181.472 201.950 1.00 80.29  ? 311 LEU A CD2 1 
ATOM   4031 N N   . SER B  1 312 ? 198.986 179.896 203.829 1.00 75.12  ? 312 SER A N   1 
ATOM   4032 C CA  . SER B  1 312 ? 197.585 179.519 203.782 1.00 73.74  ? 312 SER A CA  1 
ATOM   4033 C C   . SER B  1 312 ? 197.186 179.202 202.343 1.00 68.59  ? 312 SER A C   1 
ATOM   4034 O O   . SER B  1 312 ? 197.920 179.478 201.390 1.00 69.70  ? 312 SER A O   1 
ATOM   4035 C CB  . SER B  1 312 ? 196.709 180.635 204.351 1.00 72.48  ? 312 SER A CB  1 
ATOM   4036 O OG  . SER B  1 312 ? 195.400 180.166 204.620 1.00 76.29  ? 312 SER A OG  1 
ATOM   4037 N N   . HIS B  1 313 ? 196.002 178.605 202.187 1.00 58.34  ? 313 HIS A N   1 
ATOM   4038 C CA  . HIS B  1 313 ? 195.536 178.257 200.850 1.00 63.61  ? 313 HIS A CA  1 
ATOM   4039 C C   . HIS B  1 313 ? 195.306 179.485 199.983 1.00 62.44  ? 313 HIS A C   1 
ATOM   4040 O O   . HIS B  1 313 ? 195.327 179.374 198.753 1.00 63.43  ? 313 HIS A O   1 
ATOM   4041 C CB  . HIS B  1 313 ? 194.254 177.428 200.931 1.00 65.04  ? 313 HIS A CB  1 
ATOM   4042 C CG  . HIS B  1 313 ? 193.161 178.071 201.724 1.00 57.81  ? 313 HIS A CG  1 
ATOM   4043 N ND1 . HIS B  1 313 ? 193.174 178.127 203.101 1.00 59.19  ? 313 HIS A ND1 1 
ATOM   4044 C CD2 . HIS B  1 313 ? 192.013 178.673 201.334 1.00 57.86  ? 313 HIS A CD2 1 
ATOM   4045 C CE1 . HIS B  1 313 ? 192.084 178.741 203.524 1.00 65.17  ? 313 HIS A CE1 1 
ATOM   4046 N NE2 . HIS B  1 313 ? 191.363 179.083 202.472 1.00 68.09  ? 313 HIS A NE2 1 
ATOM   4047 N N   . GLN B  1 314 ? 195.098 180.653 200.596 1.00 62.35  ? 314 GLN A N   1 
ATOM   4048 C CA  . GLN B  1 314 ? 194.919 181.875 199.819 1.00 65.70  ? 314 GLN A CA  1 
ATOM   4049 C C   . GLN B  1 314 ? 196.170 182.202 199.015 1.00 67.35  ? 314 GLN A C   1 
ATOM   4050 O O   . GLN B  1 314 ? 196.081 182.602 197.850 1.00 70.10  ? 314 GLN A O   1 
ATOM   4051 C CB  . GLN B  1 314 ? 194.563 183.038 200.746 1.00 66.66  ? 314 GLN A CB  1 
ATOM   4052 C CG  . GLN B  1 314 ? 193.169 182.981 201.366 1.00 64.63  ? 314 GLN A CG  1 
ATOM   4053 C CD  . GLN B  1 314 ? 192.038 182.953 200.352 1.00 64.64  ? 314 GLN A CD  1 
ATOM   4054 O OE1 . GLN B  1 314 ? 192.244 183.137 199.154 1.00 57.57  ? 314 GLN A OE1 1 
ATOM   4055 N NE2 . GLN B  1 314 ? 190.826 182.724 200.839 1.00 65.53  ? 314 GLN A NE2 1 
ATOM   4056 N N   . HIS B  1 315 ? 197.347 182.035 199.620 1.00 59.61  ? 315 HIS A N   1 
ATOM   4057 C CA  . HIS B  1 315 ? 198.589 182.350 198.923 1.00 56.00  ? 315 HIS A CA  1 
ATOM   4058 C C   . HIS B  1 315 ? 198.847 181.384 197.773 1.00 60.47  ? 315 HIS A C   1 
ATOM   4059 O O   . HIS B  1 315 ? 199.295 181.798 196.697 1.00 66.88  ? 315 HIS A O   1 
ATOM   4060 C CB  . HIS B  1 315 ? 199.755 182.341 199.907 1.00 56.61  ? 315 HIS A CB  1 
ATOM   4061 C CG  . HIS B  1 315 ? 199.535 183.203 201.110 1.00 61.49  ? 315 HIS A CG  1 
ATOM   4062 N ND1 . HIS B  1 315 ? 198.664 182.861 202.122 1.00 65.05  ? 315 HIS A ND1 1 
ATOM   4063 C CD2 . HIS B  1 315 ? 200.072 184.395 201.463 1.00 63.52  ? 315 HIS A CD2 1 
ATOM   4064 C CE1 . HIS B  1 315 ? 198.674 183.805 203.046 1.00 66.99  ? 315 HIS A CE1 1 
ATOM   4065 N NE2 . HIS B  1 315 ? 199.520 184.747 202.671 1.00 65.84  ? 315 HIS A NE2 1 
ATOM   4066 N N   . LEU B  1 316 ? 198.583 180.092 197.981 1.00 50.61  ? 316 LEU A N   1 
ATOM   4067 C CA  . LEU B  1 316 ? 198.736 179.129 196.895 1.00 48.97  ? 316 LEU A CA  1 
ATOM   4068 C C   . LEU B  1 316 ? 197.754 179.419 195.769 1.00 45.19  ? 316 LEU A C   1 
ATOM   4069 O O   . LEU B  1 316 ? 198.113 179.352 194.587 1.00 48.14  ? 316 LEU A O   1 
ATOM   4070 C CB  . LEU B  1 316 ? 198.547 177.707 197.420 1.00 48.47  ? 316 LEU A CB  1 
ATOM   4071 C CG  . LEU B  1 316 ? 199.719 177.114 198.201 1.00 44.40  ? 316 LEU A CG  1 
ATOM   4072 C CD1 . LEU B  1 316 ? 199.313 175.808 198.848 1.00 45.00  ? 316 LEU A CD1 1 
ATOM   4073 C CD2 . LEU B  1 316 ? 200.916 176.912 197.295 1.00 46.04  ? 316 LEU A CD2 1 
ATOM   4074 N N   . PHE B  1 317 ? 196.510 179.756 196.120 1.00 41.44  ? 317 PHE A N   1 
ATOM   4075 C CA  . PHE B  1 317 ? 195.529 180.129 195.108 1.00 46.17  ? 317 PHE A CA  1 
ATOM   4076 C C   . PHE B  1 317 ? 195.986 181.353 194.328 1.00 52.60  ? 317 PHE A C   1 
ATOM   4077 O O   . PHE B  1 317 ? 195.834 181.410 193.105 1.00 53.11  ? 317 PHE A O   1 
ATOM   4078 C CB  . PHE B  1 317 ? 194.177 180.401 195.765 1.00 51.14  ? 317 PHE A CB  1 
ATOM   4079 C CG  . PHE B  1 317 ? 193.384 179.169 196.068 1.00 43.51  ? 317 PHE A CG  1 
ATOM   4080 C CD1 . PHE B  1 317 ? 193.388 178.096 195.202 1.00 38.59  ? 317 PHE A CD1 1 
ATOM   4081 C CD2 . PHE B  1 317 ? 192.617 179.096 197.216 1.00 54.21  ? 317 PHE A CD2 1 
ATOM   4082 C CE1 . PHE B  1 317 ? 192.652 176.968 195.483 1.00 51.39  ? 317 PHE A CE1 1 
ATOM   4083 C CE2 . PHE B  1 317 ? 191.879 177.971 197.499 1.00 48.00  ? 317 PHE A CE2 1 
ATOM   4084 C CZ  . PHE B  1 317 ? 191.895 176.906 196.632 1.00 49.53  ? 317 PHE A CZ  1 
ATOM   4085 N N   . GLU B  1 318 ? 196.550 182.343 195.021 1.00 59.76  ? 318 GLU A N   1 
ATOM   4086 C CA  . GLU B  1 318 ? 196.997 183.564 194.360 1.00 54.09  ? 318 GLU A CA  1 
ATOM   4087 C C   . GLU B  1 318 ? 198.184 183.302 193.439 1.00 54.73  ? 318 GLU A C   1 
ATOM   4088 O O   . GLU B  1 318 ? 198.245 183.846 192.331 1.00 56.03  ? 318 GLU A O   1 
ATOM   4089 C CB  . GLU B  1 318 ? 197.346 184.615 195.411 1.00 50.82  ? 318 GLU A CB  1 
ATOM   4090 C CG  . GLU B  1 318 ? 198.207 185.751 194.908 1.00 60.45  ? 318 GLU A CG  1 
ATOM   4091 C CD  . GLU B  1 318 ? 198.887 186.489 196.039 1.00 67.83  ? 318 GLU A CD  1 
ATOM   4092 O OE1 . GLU B  1 318 ? 198.177 187.087 196.873 1.00 67.78  ? 318 GLU A OE1 1 
ATOM   4093 O OE2 . GLU B  1 318 ? 200.133 186.463 196.100 1.00 63.50  ? 318 GLU A OE2 1 
ATOM   4094 N N   . ILE B  1 319 ? 199.138 182.478 193.880 1.00 57.81  ? 319 ILE A N   1 
ATOM   4095 C CA  . ILE B  1 319 ? 200.278 182.135 193.031 1.00 57.55  ? 319 ILE A CA  1 
ATOM   4096 C C   . ILE B  1 319 ? 199.805 181.390 191.790 1.00 59.10  ? 319 ILE A C   1 
ATOM   4097 O O   . ILE B  1 319 ? 200.232 181.680 190.663 1.00 58.68  ? 319 ILE A O   1 
ATOM   4098 C CB  . ILE B  1 319 ? 201.307 181.308 193.821 1.00 54.01  ? 319 ILE A CB  1 
ATOM   4099 C CG1 . ILE B  1 319 ? 202.118 182.203 194.754 1.00 62.31  ? 319 ILE A CG1 1 
ATOM   4100 C CG2 . ILE B  1 319 ? 202.237 180.571 192.876 1.00 52.37  ? 319 ILE A CG2 1 
ATOM   4101 C CD1 . ILE B  1 319 ? 202.837 181.440 195.841 1.00 61.09  ? 319 ILE A CD1 1 
ATOM   4102 N N   . ALA B  1 320 ? 198.909 180.417 191.982 1.00 49.07  ? 320 ALA A N   1 
ATOM   4103 C CA  . ALA B  1 320 ? 198.366 179.679 190.850 1.00 43.54  ? 320 ALA A CA  1 
ATOM   4104 C C   . ALA B  1 320 ? 197.634 180.606 189.895 1.00 54.79  ? 320 ALA A C   1 
ATOM   4105 O O   . ALA B  1 320 ? 197.787 180.496 188.677 1.00 62.97  ? 320 ALA A O   1 
ATOM   4106 C CB  . ALA B  1 320 ? 197.434 178.575 191.344 1.00 44.45  ? 320 ALA A CB  1 
ATOM   4107 N N   . GLY B  1 321 ? 196.849 181.541 190.432 1.00 56.53  ? 321 GLY A N   1 
ATOM   4108 C CA  . GLY B  1 321 ? 196.123 182.465 189.580 1.00 48.38  ? 321 GLY A CA  1 
ATOM   4109 C C   . GLY B  1 321 ? 197.035 183.385 188.793 1.00 46.86  ? 321 GLY A C   1 
ATOM   4110 O O   . GLY B  1 321 ? 196.805 183.630 187.611 1.00 52.15  ? 321 GLY A O   1 
ATOM   4111 N N   . PHE B  1 322 ? 198.082 183.905 189.436 1.00 46.08  ? 322 PHE A N   1 
ATOM   4112 C CA  . PHE B  1 322 ? 199.005 184.801 188.743 1.00 45.30  ? 322 PHE A CA  1 
ATOM   4113 C C   . PHE B  1 322 ? 199.760 184.068 187.640 1.00 51.35  ? 322 PHE A C   1 
ATOM   4114 O O   . PHE B  1 322 ? 199.887 184.569 186.510 1.00 63.06  ? 322 PHE A O   1 
ATOM   4115 C CB  . PHE B  1 322 ? 199.974 185.421 189.748 1.00 48.79  ? 322 PHE A CB  1 
ATOM   4116 C CG  . PHE B  1 322 ? 201.140 186.122 189.117 1.00 52.23  ? 322 PHE A CG  1 
ATOM   4117 C CD1 . PHE B  1 322 ? 200.943 187.118 188.177 1.00 60.06  ? 322 PHE A CD1 1 
ATOM   4118 C CD2 . PHE B  1 322 ? 202.436 185.794 189.476 1.00 54.90  ? 322 PHE A CD2 1 
ATOM   4119 C CE1 . PHE B  1 322 ? 202.016 187.767 187.601 1.00 60.14  ? 322 PHE A CE1 1 
ATOM   4120 C CE2 . PHE B  1 322 ? 203.512 186.439 188.904 1.00 57.97  ? 322 PHE A CE2 1 
ATOM   4121 C CZ  . PHE B  1 322 ? 203.302 187.427 187.966 1.00 63.64  ? 322 PHE A CZ  1 
ATOM   4122 N N   . LEU B  1 323 ? 200.265 182.872 187.944 1.00 54.19  ? 323 LEU A N   1 
ATOM   4123 C CA  . LEU B  1 323 ? 200.955 182.109 186.914 1.00 54.62  ? 323 LEU A CA  1 
ATOM   4124 C C   . LEU B  1 323 ? 199.996 181.671 185.814 1.00 48.57  ? 323 LEU A C   1 
ATOM   4125 O O   . LEU B  1 323 ? 200.398 181.563 184.652 1.00 47.65  ? 323 LEU A O   1 
ATOM   4126 C CB  . LEU B  1 323 ? 201.667 180.913 187.539 1.00 53.21  ? 323 LEU A CB  1 
ATOM   4127 C CG  . LEU B  1 323 ? 202.754 181.249 188.561 1.00 52.83  ? 323 LEU A CG  1 
ATOM   4128 C CD1 . LEU B  1 323 ? 203.422 179.983 189.062 1.00 51.05  ? 323 LEU A CD1 1 
ATOM   4129 C CD2 . LEU B  1 323 ? 203.775 182.196 187.959 1.00 57.21  ? 323 LEU A CD2 1 
ATOM   4130 N N   . GLY B  1 324 ? 198.725 181.444 186.149 1.00 50.35  ? 324 GLY A N   1 
ATOM   4131 C CA  . GLY B  1 324 ? 197.734 181.181 185.121 1.00 48.45  ? 324 GLY A CA  1 
ATOM   4132 C C   . GLY B  1 324 ? 197.464 182.391 184.251 1.00 52.52  ? 324 GLY A C   1 
ATOM   4133 O O   . GLY B  1 324 ? 197.218 182.258 183.051 1.00 59.72  ? 324 GLY A O   1 
ATOM   4134 N N   . ILE B  1 325 ? 197.492 183.587 184.843 1.00 51.97  ? 325 ILE A N   1 
ATOM   4135 C CA  . ILE B  1 325 ? 197.377 184.811 184.055 1.00 49.59  ? 325 ILE A CA  1 
ATOM   4136 C C   . ILE B  1 325 ? 198.499 184.869 183.034 1.00 48.18  ? 325 ILE A C   1 
ATOM   4137 O O   . ILE B  1 325 ? 198.279 185.142 181.848 1.00 51.88  ? 325 ILE A O   1 
ATOM   4138 C CB  . ILE B  1 325 ? 197.405 186.056 184.963 1.00 49.95  ? 325 ILE A CB  1 
ATOM   4139 C CG1 . ILE B  1 325 ? 196.216 186.087 185.917 1.00 50.61  ? 325 ILE A CG1 1 
ATOM   4140 C CG2 . ILE B  1 325 ? 197.431 187.319 184.123 1.00 47.75  ? 325 ILE A CG2 1 
ATOM   4141 C CD1 . ILE B  1 325 ? 194.973 185.520 185.342 1.00 53.56  ? 325 ILE A CD1 1 
ATOM   4142 N N   . LEU B  1 326 ? 199.725 184.607 183.488 1.00 44.69  ? 326 LEU A N   1 
ATOM   4143 C CA  . LEU B  1 326 ? 200.866 184.653 182.579 1.00 48.68  ? 326 LEU A CA  1 
ATOM   4144 C C   . LEU B  1 326 ? 200.773 183.574 181.506 1.00 51.47  ? 326 LEU A C   1 
ATOM   4145 O O   . LEU B  1 326 ? 201.081 183.824 180.334 1.00 47.81  ? 326 LEU A O   1 
ATOM   4146 C CB  . LEU B  1 326 ? 202.163 184.524 183.367 1.00 42.27  ? 326 LEU A CB  1 
ATOM   4147 C CG  . LEU B  1 326 ? 202.394 185.728 184.272 1.00 49.65  ? 326 LEU A CG  1 
ATOM   4148 C CD1 . LEU B  1 326 ? 203.708 185.580 184.966 1.00 46.89  ? 326 LEU A CD1 1 
ATOM   4149 C CD2 . LEU B  1 326 ? 202.354 187.014 183.469 1.00 49.65  ? 326 LEU A CD2 1 
ATOM   4150 N N   . TRP B  1 327 ? 200.350 182.367 181.886 1.00 52.08  ? 327 TRP A N   1 
ATOM   4151 C CA  . TRP B  1 327 ? 200.201 181.288 180.916 1.00 46.11  ? 327 TRP A CA  1 
ATOM   4152 C C   . TRP B  1 327 ? 199.148 181.627 179.869 1.00 47.91  ? 327 TRP A C   1 
ATOM   4153 O O   . TRP B  1 327 ? 199.357 181.404 178.670 1.00 55.23  ? 327 TRP A O   1 
ATOM   4154 C CB  . TRP B  1 327 ? 199.843 179.990 181.640 1.00 44.94  ? 327 TRP A CB  1 
ATOM   4155 C CG  . TRP B  1 327 ? 199.623 178.827 180.735 1.00 40.04  ? 327 TRP A CG  1 
ATOM   4156 C CD1 . TRP B  1 327 ? 200.579 178.070 180.129 1.00 42.56  ? 327 TRP A CD1 1 
ATOM   4157 C CD2 . TRP B  1 327 ? 198.363 178.279 180.336 1.00 45.33  ? 327 TRP A CD2 1 
ATOM   4158 N NE1 . TRP B  1 327 ? 199.993 177.085 179.374 1.00 51.92  ? 327 TRP A NE1 1 
ATOM   4159 C CE2 . TRP B  1 327 ? 198.632 177.194 179.483 1.00 49.93  ? 327 TRP A CE2 1 
ATOM   4160 C CE3 . TRP B  1 327 ? 197.034 178.602 180.614 1.00 44.87  ? 327 TRP A CE3 1 
ATOM   4161 C CZ2 . TRP B  1 327 ? 197.623 176.431 178.907 1.00 49.01  ? 327 TRP A CZ2 1 
ATOM   4162 C CZ3 . TRP B  1 327 ? 196.034 177.845 180.042 1.00 42.20  ? 327 TRP A CZ3 1 
ATOM   4163 C CH2 . TRP B  1 327 ? 196.333 176.772 179.198 1.00 46.69  ? 327 TRP A CH2 1 
ATOM   4164 N N   . CYS B  1 328 ? 198.011 182.175 180.303 1.00 45.91  ? 328 CYS A N   1 
ATOM   4165 C CA  . CYS B  1 328 ? 196.957 182.548 179.369 1.00 40.33  ? 328 CYS A CA  1 
ATOM   4166 C C   . CYS B  1 328 ? 197.412 183.664 178.444 1.00 47.26  ? 328 CYS A C   1 
ATOM   4167 O O   . CYS B  1 328 ? 197.105 183.651 177.248 1.00 54.27  ? 328 CYS A O   1 
ATOM   4168 C CB  . CYS B  1 328 ? 195.703 182.964 180.133 1.00 41.53  ? 328 CYS A CB  1 
ATOM   4169 S SG  . CYS B  1 328 ? 194.720 181.587 180.743 1.00 52.34  ? 328 CYS A SG  1 
ATOM   4170 N N   . LEU B  1 329 ? 198.147 184.642 178.978 1.00 49.86  ? 329 LEU A N   1 
ATOM   4171 C CA  . LEU B  1 329 ? 198.651 185.721 178.137 1.00 55.76  ? 329 LEU A CA  1 
ATOM   4172 C C   . LEU B  1 329 ? 199.646 185.201 177.106 1.00 57.94  ? 329 LEU A C   1 
ATOM   4173 O O   . LEU B  1 329 ? 199.608 185.608 175.939 1.00 56.77  ? 329 LEU A O   1 
ATOM   4174 C CB  . LEU B  1 329 ? 199.284 186.807 179.004 1.00 53.37  ? 329 LEU A CB  1 
ATOM   4175 C CG  . LEU B  1 329 ? 198.282 187.743 179.679 1.00 45.48  ? 329 LEU A CG  1 
ATOM   4176 C CD1 . LEU B  1 329 ? 198.953 188.563 180.764 1.00 54.08  ? 329 LEU A CD1 1 
ATOM   4177 C CD2 . LEU B  1 329 ? 197.628 188.643 178.648 1.00 48.52  ? 329 LEU A CD2 1 
ATOM   4178 N N   . SER B  1 330 ? 200.537 184.295 177.514 1.00 47.59  ? 330 SER A N   1 
ATOM   4179 C CA  . SER B  1 330 ? 201.494 183.728 176.570 1.00 51.03  ? 330 SER A CA  1 
ATOM   4180 C C   . SER B  1 330 ? 200.791 182.915 175.490 1.00 57.51  ? 330 SER A C   1 
ATOM   4181 O O   . SER B  1 330 ? 201.135 183.012 174.306 1.00 60.83  ? 330 SER A O   1 
ATOM   4182 C CB  . SER B  1 330 ? 202.515 182.869 177.312 1.00 53.37  ? 330 SER A CB  1 
ATOM   4183 O OG  . SER B  1 330 ? 203.237 182.050 176.412 1.00 61.17  ? 330 SER A OG  1 
ATOM   4184 N N   . LEU B  1 331 ? 199.797 182.112 175.874 1.00 54.88  ? 331 LEU A N   1 
ATOM   4185 C CA  . LEU B  1 331 ? 199.052 181.340 174.885 1.00 50.40  ? 331 LEU A CA  1 
ATOM   4186 C C   . LEU B  1 331 ? 198.291 182.251 173.930 1.00 63.19  ? 331 LEU A C   1 
ATOM   4187 O O   . LEU B  1 331 ? 198.236 181.989 172.722 1.00 65.03  ? 331 LEU A O   1 
ATOM   4188 C CB  . LEU B  1 331 ? 198.104 180.368 175.585 1.00 47.42  ? 331 LEU A CB  1 
ATOM   4189 C CG  . LEU B  1 331 ? 197.579 179.201 174.748 1.00 53.76  ? 331 LEU A CG  1 
ATOM   4190 C CD1 . LEU B  1 331 ? 198.613 178.745 173.741 1.00 63.20  ? 331 LEU A CD1 1 
ATOM   4191 C CD2 . LEU B  1 331 ? 197.177 178.044 175.643 1.00 51.66  ? 331 LEU A CD2 1 
ATOM   4192 N N   . LEU B  1 332 ? 197.694 183.326 174.451 1.00 63.90  ? 332 LEU A N   1 
ATOM   4193 C CA  . LEU B  1 332 ? 196.993 184.276 173.594 1.00 61.40  ? 332 LEU A CA  1 
ATOM   4194 C C   . LEU B  1 332 ? 197.947 184.937 172.611 1.00 58.73  ? 332 LEU A C   1 
ATOM   4195 O O   . LEU B  1 332 ? 197.623 185.092 171.428 1.00 62.51  ? 332 LEU A O   1 
ATOM   4196 C CB  . LEU B  1 332 ? 196.291 185.331 174.448 1.00 56.21  ? 332 LEU A CB  1 
ATOM   4197 C CG  . LEU B  1 332 ? 194.895 184.984 174.963 1.00 54.85  ? 332 LEU A CG  1 
ATOM   4198 C CD1 . LEU B  1 332 ? 194.204 186.231 175.467 1.00 59.95  ? 332 LEU A CD1 1 
ATOM   4199 C CD2 . LEU B  1 332 ? 194.074 184.323 173.873 1.00 58.66  ? 332 LEU A CD2 1 
ATOM   4200 N N   . ALA B  1 333 ? 199.131 185.334 173.083 1.00 46.47  ? 333 ALA A N   1 
ATOM   4201 C CA  . ALA B  1 333 ? 200.123 185.919 172.188 1.00 58.72  ? 333 ALA A CA  1 
ATOM   4202 C C   . ALA B  1 333 ? 200.578 184.914 171.140 1.00 67.06  ? 333 ALA A C   1 
ATOM   4203 O O   . ALA B  1 333 ? 200.911 185.288 170.010 1.00 69.70  ? 333 ALA A O   1 
ATOM   4204 C CB  . ALA B  1 333 ? 201.314 186.434 172.993 1.00 61.11  ? 333 ALA A CB  1 
ATOM   4205 N N   . CYS B  1 334 ? 200.620 183.631 171.504 1.00 73.12  ? 334 CYS A N   1 
ATOM   4206 C CA  . CYS B  1 334 ? 200.948 182.601 170.525 1.00 70.19  ? 334 CYS A CA  1 
ATOM   4207 C C   . CYS B  1 334 ? 199.855 182.468 169.472 1.00 75.02  ? 334 CYS A C   1 
ATOM   4208 O O   . CYS B  1 334 ? 200.148 182.273 168.287 1.00 79.35  ? 334 CYS A O   1 
ATOM   4209 C CB  . CYS B  1 334 ? 201.177 181.265 171.226 1.00 67.64  ? 334 CYS A CB  1 
ATOM   4210 S SG  . CYS B  1 334 ? 202.857 181.019 171.827 1.00 86.10  ? 334 CYS A SG  1 
ATOM   4211 N N   . PHE B  1 335 ? 198.589 182.560 169.887 1.00 73.75  ? 335 PHE A N   1 
ATOM   4212 C CA  . PHE B  1 335 ? 197.487 182.387 168.944 1.00 75.57  ? 335 PHE A CA  1 
ATOM   4213 C C   . PHE B  1 335 ? 197.499 183.473 167.876 1.00 79.05  ? 335 PHE A C   1 
ATOM   4214 O O   . PHE B  1 335 ? 197.471 183.180 166.675 1.00 76.10  ? 335 PHE A O   1 
ATOM   4215 C CB  . PHE B  1 335 ? 196.154 182.373 169.690 1.00 73.13  ? 335 PHE A CB  1 
ATOM   4216 C CG  . PHE B  1 335 ? 195.676 180.997 170.034 1.00 76.25  ? 335 PHE A CG  1 
ATOM   4217 C CD1 . PHE B  1 335 ? 195.084 180.197 169.074 1.00 79.00  ? 335 PHE A CD1 1 
ATOM   4218 C CD2 . PHE B  1 335 ? 195.828 180.499 171.314 1.00 77.14  ? 335 PHE A CD2 1 
ATOM   4219 C CE1 . PHE B  1 335 ? 194.649 178.927 169.388 1.00 79.49  ? 335 PHE A CE1 1 
ATOM   4220 C CE2 . PHE B  1 335 ? 195.395 179.231 171.633 1.00 78.32  ? 335 PHE A CE2 1 
ATOM   4221 C CZ  . PHE B  1 335 ? 194.804 178.444 170.669 1.00 79.86  ? 335 PHE A CZ  1 
ATOM   4222 N N   . PHE B  1 336 ? 197.544 184.737 168.294 1.00 79.77  ? 336 PHE A N   1 
ATOM   4223 C CA  . PHE B  1 336 ? 197.735 185.860 167.383 1.00 77.31  ? 336 PHE A CA  1 
ATOM   4224 C C   . PHE B  1 336 ? 198.888 186.707 167.897 1.00 74.79  ? 336 PHE A C   1 
ATOM   4225 O O   . PHE B  1 336 ? 198.966 186.990 169.096 1.00 74.30  ? 336 PHE A O   1 
ATOM   4226 C CB  . PHE B  1 336 ? 196.453 186.691 167.224 1.00 75.43  ? 336 PHE A CB  1 
ATOM   4227 C CG  . PHE B  1 336 ? 195.627 186.815 168.480 1.00 73.18  ? 336 PHE A CG  1 
ATOM   4228 C CD1 . PHE B  1 336 ? 196.129 187.431 169.612 1.00 70.68  ? 336 PHE A CD1 1 
ATOM   4229 C CD2 . PHE B  1 336 ? 194.332 186.325 168.513 1.00 70.15  ? 336 PHE A CD2 1 
ATOM   4230 C CE1 . PHE B  1 336 ? 195.363 187.543 170.754 1.00 72.50  ? 336 PHE A CE1 1 
ATOM   4231 C CE2 . PHE B  1 336 ? 193.561 186.436 169.652 1.00 71.69  ? 336 PHE A CE2 1 
ATOM   4232 C CZ  . PHE B  1 336 ? 194.077 187.046 170.774 1.00 73.91  ? 336 PHE A CZ  1 
ATOM   4233 N N   . ALA B  1 337 ? 199.791 187.089 166.999 1.00 80.93  ? 337 ALA A N   1 
ATOM   4234 C CA  . ALA B  1 337 ? 200.973 187.844 167.392 1.00 83.39  ? 337 ALA A CA  1 
ATOM   4235 C C   . ALA B  1 337 ? 200.643 189.327 167.490 1.00 83.35  ? 337 ALA A C   1 
ATOM   4236 O O   . ALA B  1 337 ? 200.475 189.994 166.461 1.00 82.20  ? 337 ALA A O   1 
ATOM   4237 C CB  . ALA B  1 337 ? 202.113 187.613 166.399 1.00 82.09  ? 337 ALA A CB  1 
ATOM   4238 N N   . PRO B  1 338 ? 200.535 189.878 168.702 1.00 85.24  ? 338 PRO A N   1 
ATOM   4239 C CA  . PRO B  1 338 ? 200.235 191.314 168.819 1.00 85.75  ? 338 PRO A CA  1 
ATOM   4240 C C   . PRO B  1 338 ? 201.304 192.194 168.200 1.00 83.80  ? 338 PRO A C   1 
ATOM   4241 O O   . PRO B  1 338 ? 200.987 193.244 167.627 1.00 87.46  ? 338 PRO A O   1 
ATOM   4242 C CB  . PRO B  1 338 ? 200.123 191.531 170.337 1.00 87.00  ? 338 PRO A CB  1 
ATOM   4243 C CG  . PRO B  1 338 ? 200.107 190.156 170.948 1.00 86.02  ? 338 PRO A CG  1 
ATOM   4244 C CD  . PRO B  1 338 ? 200.850 189.278 170.006 1.00 86.05  ? 338 PRO A CD  1 
ATOM   4245 N N   . ILE B  1 339 ? 202.565 191.790 168.292 1.00 78.19  ? 339 ILE A N   1 
ATOM   4246 C CA  . ILE B  1 339 ? 203.683 192.541 167.738 1.00 81.06  ? 339 ILE A CA  1 
ATOM   4247 C C   . ILE B  1 339 ? 204.302 191.686 166.643 1.00 82.81  ? 339 ILE A C   1 
ATOM   4248 O O   . ILE B  1 339 ? 204.797 190.583 166.907 1.00 82.88  ? 339 ILE A O   1 
ATOM   4249 C CB  . ILE B  1 339 ? 204.722 192.914 168.807 1.00 78.94  ? 339 ILE A CB  1 
ATOM   4250 C CG1 . ILE B  1 339 ? 204.055 193.307 170.132 1.00 78.89  ? 339 ILE A CG1 1 
ATOM   4251 C CG2 . ILE B  1 339 ? 205.619 194.035 168.307 1.00 80.48  ? 339 ILE A CG2 1 
ATOM   4252 C CD1 . ILE B  1 339 ? 203.834 192.155 171.103 1.00 78.51  ? 339 ILE A CD1 1 
ATOM   4253 N N   . SER B  1 340 ? 204.275 192.191 165.409 1.00 87.94  ? 340 SER A N   1 
ATOM   4254 C CA  . SER B  1 340 ? 204.831 191.446 164.287 1.00 87.24  ? 340 SER A CA  1 
ATOM   4255 C C   . SER B  1 340 ? 206.348 191.339 164.356 1.00 84.90  ? 340 SER A C   1 
ATOM   4256 O O   . SER B  1 340 ? 206.920 190.434 163.740 1.00 82.97  ? 340 SER A O   1 
ATOM   4257 C CB  . SER B  1 340 ? 204.414 192.097 162.967 1.00 88.99  ? 340 SER A CB  1 
ATOM   4258 O OG  . SER B  1 340 ? 204.532 193.507 163.034 1.00 85.08  ? 340 SER A OG  1 
ATOM   4259 N N   . VAL B  1 341 ? 207.010 192.240 165.084 1.00 82.92  ? 341 VAL A N   1 
ATOM   4260 C CA  . VAL B  1 341 ? 208.466 192.203 165.159 1.00 82.88  ? 341 VAL A CA  1 
ATOM   4261 C C   . VAL B  1 341 ? 208.934 190.995 165.960 1.00 83.35  ? 341 VAL A C   1 
ATOM   4262 O O   . VAL B  1 341 ? 209.866 190.290 165.557 1.00 84.61  ? 341 VAL A O   1 
ATOM   4263 C CB  . VAL B  1 341 ? 209.003 193.516 165.755 1.00 84.87  ? 341 VAL A CB  1 
ATOM   4264 C CG1 . VAL B  1 341 ? 210.457 193.718 165.360 1.00 83.83  ? 341 VAL A CG1 1 
ATOM   4265 C CG2 . VAL B  1 341 ? 208.151 194.690 165.306 1.00 84.89  ? 341 VAL A CG2 1 
ATOM   4266 N N   . ILE B  1 342 ? 208.302 190.736 167.100 1.00 79.89  ? 342 ILE A N   1 
ATOM   4267 C CA  . ILE B  1 342 ? 208.707 189.639 167.976 1.00 80.55  ? 342 ILE A CA  1 
ATOM   4268 C C   . ILE B  1 342 ? 208.163 188.321 167.431 1.00 81.70  ? 342 ILE A C   1 
ATOM   4269 O O   . ILE B  1 342 ? 206.960 188.206 167.154 1.00 81.57  ? 342 ILE A O   1 
ATOM   4270 C CB  . ILE B  1 342 ? 208.266 189.897 169.429 1.00 76.63  ? 342 ILE A CB  1 
ATOM   4271 C CG1 . ILE B  1 342 ? 208.834 188.830 170.367 1.00 78.92  ? 342 ILE A CG1 1 
ATOM   4272 C CG2 . ILE B  1 342 ? 206.754 190.012 169.548 1.00 76.25  ? 342 ILE A CG2 1 
ATOM   4273 C CD1 . ILE B  1 342 ? 209.343 189.390 171.678 1.00 79.01  ? 342 ILE A CD1 1 
ATOM   4274 N N   . PRO B  1 343 ? 209.015 187.320 167.222 1.00 76.13  ? 343 PRO A N   1 
ATOM   4275 C CA  . PRO B  1 343 ? 208.534 186.038 166.698 1.00 73.68  ? 343 PRO A CA  1 
ATOM   4276 C C   . PRO B  1 343 ? 207.641 185.321 167.696 1.00 78.45  ? 343 PRO A C   1 
ATOM   4277 O O   . PRO B  1 343 ? 207.746 185.509 168.911 1.00 80.03  ? 343 PRO A O   1 
ATOM   4278 C CB  . PRO B  1 343 ? 209.822 185.249 166.437 1.00 75.03  ? 343 PRO A CB  1 
ATOM   4279 C CG  . PRO B  1 343 ? 210.927 186.256 166.470 1.00 75.15  ? 343 PRO A CG  1 
ATOM   4280 C CD  . PRO B  1 343 ? 210.477 187.342 167.386 1.00 76.61  ? 343 PRO A CD  1 
ATOM   4281 N N   . THR B  1 344 ? 206.749 184.483 167.162 1.00 80.55  ? 344 THR A N   1 
ATOM   4282 C CA  . THR B  1 344 ? 205.750 183.819 167.992 1.00 81.77  ? 344 THR A CA  1 
ATOM   4283 C C   . THR B  1 344 ? 206.344 182.753 168.903 1.00 80.61  ? 344 THR A C   1 
ATOM   4284 O O   . THR B  1 344 ? 205.741 182.437 169.933 1.00 79.54  ? 344 THR A O   1 
ATOM   4285 C CB  . THR B  1 344 ? 204.666 183.195 167.114 1.00 84.50  ? 344 THR A CB  1 
ATOM   4286 O OG1 . THR B  1 344 ? 203.843 182.332 167.909 1.00 84.65  ? 344 THR A OG1 1 
ATOM   4287 C CG2 . THR B  1 344 ? 205.289 182.402 165.983 1.00 82.41  ? 344 THR A CG2 1 
ATOM   4288 N N   . TYR B  1 345 ? 207.501 182.189 168.557 1.00 82.03  ? 345 TYR A N   1 
ATOM   4289 C CA  . TYR B  1 345 ? 208.123 181.200 169.429 1.00 85.63  ? 345 TYR A CA  1 
ATOM   4290 C C   . TYR B  1 345 ? 208.773 181.820 170.656 1.00 82.34  ? 345 TYR A C   1 
ATOM   4291 O O   . TYR B  1 345 ? 209.227 181.082 171.536 1.00 80.73  ? 345 TYR A O   1 
ATOM   4292 C CB  . TYR B  1 345 ? 209.162 180.378 168.659 1.00 86.15  ? 345 TYR A CB  1 
ATOM   4293 C CG  . TYR B  1 345 ? 210.201 181.193 167.923 1.00 83.50  ? 345 TYR A CG  1 
ATOM   4294 C CD1 . TYR B  1 345 ? 211.252 181.793 168.602 1.00 78.99  ? 345 TYR A CD1 1 
ATOM   4295 C CD2 . TYR B  1 345 ? 210.147 181.338 166.544 1.00 83.47  ? 345 TYR A CD2 1 
ATOM   4296 C CE1 . TYR B  1 345 ? 212.203 182.532 167.935 1.00 79.91  ? 345 TYR A CE1 1 
ATOM   4297 C CE2 . TYR B  1 345 ? 211.098 182.071 165.866 1.00 83.53  ? 345 TYR A CE2 1 
ATOM   4298 C CZ  . TYR B  1 345 ? 212.125 182.666 166.567 1.00 84.17  ? 345 TYR A CZ  1 
ATOM   4299 O OH  . TYR B  1 345 ? 213.076 183.401 165.897 1.00 85.62  ? 345 TYR A OH  1 
ATOM   4300 N N   . VAL B  1 346 ? 208.843 183.150 170.728 1.00 71.20  ? 346 VAL A N   1 
ATOM   4301 C CA  . VAL B  1 346 ? 209.431 183.799 171.892 1.00 68.52  ? 346 VAL A CA  1 
ATOM   4302 C C   . VAL B  1 346 ? 208.519 183.660 173.102 1.00 69.58  ? 346 VAL A C   1 
ATOM   4303 O O   . VAL B  1 346 ? 208.997 183.576 174.237 1.00 70.91  ? 346 VAL A O   1 
ATOM   4304 C CB  . VAL B  1 346 ? 209.731 185.275 171.573 1.00 67.16  ? 346 VAL A CB  1 
ATOM   4305 C CG1 . VAL B  1 346 ? 210.234 186.007 172.809 1.00 65.31  ? 346 VAL A CG1 1 
ATOM   4306 C CG2 . VAL B  1 346 ? 210.735 185.373 170.439 1.00 71.04  ? 346 VAL A CG2 1 
ATOM   4307 N N   . TYR B  1 347 ? 207.215 183.641 172.872 1.00 60.99  ? 347 TYR A N   1 
ATOM   4308 C CA  . TYR B  1 347 ? 206.284 183.589 173.994 1.00 61.07  ? 347 TYR A CA  1 
ATOM   4309 C C   . TYR B  1 347 ? 206.404 182.346 174.889 1.00 67.76  ? 347 TYR A C   1 
ATOM   4310 O O   . TYR B  1 347 ? 206.438 182.483 176.106 1.00 68.81  ? 347 TYR A O   1 
ATOM   4311 C CB  . TYR B  1 347 ? 204.852 183.815 173.523 1.00 55.79  ? 347 TYR A CB  1 
ATOM   4312 C CG  . TYR B  1 347 ? 204.689 185.001 172.607 1.00 64.69  ? 347 TYR A CG  1 
ATOM   4313 C CD1 . TYR B  1 347 ? 204.966 186.289 173.043 1.00 66.68  ? 347 TYR A CD1 1 
ATOM   4314 C CD2 . TYR B  1 347 ? 204.244 184.833 171.309 1.00 67.12  ? 347 TYR A CD2 1 
ATOM   4315 C CE1 . TYR B  1 347 ? 204.810 187.374 172.201 1.00 61.23  ? 347 TYR A CE1 1 
ATOM   4316 C CE2 . TYR B  1 347 ? 204.088 185.908 170.462 1.00 70.35  ? 347 TYR A CE2 1 
ATOM   4317 C CZ  . TYR B  1 347 ? 204.369 187.173 170.912 1.00 66.94  ? 347 TYR A CZ  1 
ATOM   4318 O OH  . TYR B  1 347 ? 204.200 188.231 170.057 1.00 70.45  ? 347 TYR A OH  1 
ATOM   4319 N N   . PRO B  1 348 ? 206.465 181.135 174.308 1.00 64.11  ? 348 PRO A N   1 
ATOM   4320 C CA  . PRO B  1 348 ? 206.599 180.005 175.224 1.00 48.68  ? 348 PRO A CA  1 
ATOM   4321 C C   . PRO B  1 348 ? 207.859 180.106 176.032 1.00 53.44  ? 348 PRO A C   1 
ATOM   4322 O O   . PRO B  1 348 ? 207.860 179.709 177.188 1.00 64.18  ? 348 PRO A O   1 
ATOM   4323 C CB  . PRO B  1 348 ? 206.723 178.817 174.288 1.00 56.94  ? 348 PRO A CB  1 
ATOM   4324 C CG  . PRO B  1 348 ? 205.972 179.216 173.076 1.00 61.65  ? 348 PRO A CG  1 
ATOM   4325 C CD  . PRO B  1 348 ? 206.245 180.681 172.923 1.00 69.35  ? 348 PRO A CD  1 
ATOM   4326 N N   . LEU B  1 349 ? 208.922 180.634 175.445 1.00 57.26  ? 349 LEU A N   1 
ATOM   4327 C CA  . LEU B  1 349 ? 210.195 180.679 176.141 1.00 59.50  ? 349 LEU A CA  1 
ATOM   4328 C C   . LEU B  1 349 ? 210.183 181.751 177.219 1.00 59.30  ? 349 LEU A C   1 
ATOM   4329 O O   . LEU B  1 349 ? 210.722 181.535 178.307 1.00 62.53  ? 349 LEU A O   1 
ATOM   4330 C CB  . LEU B  1 349 ? 211.337 180.934 175.154 1.00 49.82  ? 349 LEU A CB  1 
ATOM   4331 C CG  . LEU B  1 349 ? 212.745 180.608 175.657 1.00 51.51  ? 349 LEU A CG  1 
ATOM   4332 C CD1 . LEU B  1 349 ? 213.025 179.113 175.563 1.00 58.06  ? 349 LEU A CD1 1 
ATOM   4333 C CD2 . LEU B  1 349 ? 213.770 181.398 174.862 1.00 59.62  ? 349 LEU A CD2 1 
ATOM   4334 N N   . ALA B  1 350 ? 209.549 182.894 176.943 1.00 58.61  ? 350 ALA A N   1 
ATOM   4335 C CA  . ALA B  1 350 ? 209.448 183.955 177.936 1.00 59.95  ? 350 ALA A CA  1 
ATOM   4336 C C   . ALA B  1 350 ? 208.612 183.518 179.128 1.00 65.28  ? 350 ALA A C   1 
ATOM   4337 O O   . ALA B  1 350 ? 208.933 183.854 180.272 1.00 69.00  ? 350 ALA A O   1 
ATOM   4338 C CB  . ALA B  1 350 ? 208.851 185.210 177.301 1.00 62.24  ? 350 ALA A CB  1 
ATOM   4339 N N   . LEU B  1 351 ? 207.533 182.769 178.883 1.00 63.62  ? 351 LEU A N   1 
ATOM   4340 C CA  . LEU B  1 351 ? 206.688 182.327 179.989 1.00 58.25  ? 351 LEU A CA  1 
ATOM   4341 C C   . LEU B  1 351 ? 207.472 181.457 180.966 1.00 57.45  ? 351 LEU A C   1 
ATOM   4342 O O   . LEU B  1 351 ? 207.479 181.707 182.178 1.00 63.94  ? 351 LEU A O   1 
ATOM   4343 C CB  . LEU B  1 351 ? 205.472 181.573 179.452 1.00 52.88  ? 351 LEU A CB  1 
ATOM   4344 C CG  . LEU B  1 351 ? 204.765 180.658 180.454 1.00 47.54  ? 351 LEU A CG  1 
ATOM   4345 C CD1 . LEU B  1 351 ? 204.059 181.483 181.515 1.00 50.51  ? 351 LEU A CD1 1 
ATOM   4346 C CD2 . LEU B  1 351 ? 203.785 179.740 179.747 1.00 51.67  ? 351 LEU A CD2 1 
ATOM   4347 N N   . TYR B  1 352 ? 208.165 180.440 180.452 1.00 49.44  ? 352 TYR A N   1 
ATOM   4348 C CA  . TYR B  1 352 ? 208.884 179.536 181.339 1.00 52.03  ? 352 TYR A CA  1 
ATOM   4349 C C   . TYR B  1 352 ? 210.150 180.175 181.892 1.00 61.26  ? 352 TYR A C   1 
ATOM   4350 O O   . TYR B  1 352 ? 210.562 179.851 183.011 1.00 72.19  ? 352 TYR A O   1 
ATOM   4351 C CB  . TYR B  1 352 ? 209.194 178.229 180.615 1.00 48.39  ? 352 TYR A CB  1 
ATOM   4352 C CG  . TYR B  1 352 ? 207.943 177.474 180.235 1.00 55.09  ? 352 TYR A CG  1 
ATOM   4353 C CD1 . TYR B  1 352 ? 206.980 177.170 181.185 1.00 58.13  ? 352 TYR A CD1 1 
ATOM   4354 C CD2 . TYR B  1 352 ? 207.710 177.092 178.927 1.00 59.66  ? 352 TYR A CD2 1 
ATOM   4355 C CE1 . TYR B  1 352 ? 205.830 176.491 180.844 1.00 53.80  ? 352 TYR A CE1 1 
ATOM   4356 C CE2 . TYR B  1 352 ? 206.563 176.412 178.575 1.00 60.94  ? 352 TYR A CE2 1 
ATOM   4357 C CZ  . TYR B  1 352 ? 205.628 176.115 179.537 1.00 57.45  ? 352 TYR A CZ  1 
ATOM   4358 O OH  . TYR B  1 352 ? 204.486 175.437 179.184 1.00 61.60  ? 352 TYR A OH  1 
ATOM   4359 N N   . GLY B  1 353 ? 210.765 181.097 181.150 1.00 62.82  ? 353 GLY A N   1 
ATOM   4360 C CA  . GLY B  1 353 ? 211.867 181.855 181.711 1.00 65.93  ? 353 GLY A CA  1 
ATOM   4361 C C   . GLY B  1 353 ? 211.433 182.709 182.885 1.00 70.42  ? 353 GLY A C   1 
ATOM   4362 O O   . GLY B  1 353 ? 212.129 182.783 183.900 1.00 70.09  ? 353 GLY A O   1 
ATOM   4363 N N   . PHE B  1 354 ? 210.273 183.361 182.767 1.00 75.54  ? 354 PHE A N   1 
ATOM   4364 C CA  . PHE B  1 354 ? 209.761 184.132 183.891 1.00 72.12  ? 354 PHE A CA  1 
ATOM   4365 C C   . PHE B  1 354 ? 209.417 183.208 185.047 1.00 72.06  ? 354 PHE A C   1 
ATOM   4366 O O   . PHE B  1 354 ? 209.638 183.560 186.205 1.00 74.64  ? 354 PHE A O   1 
ATOM   4367 C CB  . PHE B  1 354 ? 208.546 184.971 183.472 1.00 68.94  ? 354 PHE A CB  1 
ATOM   4368 C CG  . PHE B  1 354 ? 207.865 185.702 184.619 1.00 74.63  ? 354 PHE A CG  1 
ATOM   4369 C CD1 . PHE B  1 354 ? 207.143 185.029 185.599 1.00 74.32  ? 354 PHE A CD1 1 
ATOM   4370 C CD2 . PHE B  1 354 ? 207.970 187.079 184.716 1.00 76.98  ? 354 PHE A CD2 1 
ATOM   4371 C CE1 . PHE B  1 354 ? 206.556 185.713 186.644 1.00 76.58  ? 354 PHE A CE1 1 
ATOM   4372 C CE2 . PHE B  1 354 ? 207.370 187.767 185.754 1.00 76.64  ? 354 PHE A CE2 1 
ATOM   4373 C CZ  . PHE B  1 354 ? 206.660 187.083 186.716 1.00 77.19  ? 354 PHE A CZ  1 
ATOM   4374 N N   . MET B  1 355 ? 208.855 182.033 184.758 1.00 73.73  ? 355 MET A N   1 
ATOM   4375 C CA  . MET B  1 355 ? 208.544 181.093 185.832 1.00 71.12  ? 355 MET A CA  1 
ATOM   4376 C C   . MET B  1 355 ? 209.807 180.688 186.585 1.00 73.66  ? 355 MET A C   1 
ATOM   4377 O O   . MET B  1 355 ? 209.830 180.669 187.822 1.00 79.27  ? 355 MET A O   1 
ATOM   4378 C CB  . MET B  1 355 ? 207.833 179.864 185.265 1.00 65.80  ? 355 MET A CB  1 
ATOM   4379 C CG  . MET B  1 355 ? 206.337 179.840 185.523 1.00 70.32  ? 355 MET A CG  1 
ATOM   4380 S SD  . MET B  1 355 ? 205.509 178.471 184.693 1.00 95.50  ? 355 MET A SD  1 
ATOM   4381 C CE  . MET B  1 355 ? 203.813 179.041 184.710 1.00 69.01  ? 355 MET A CE  1 
ATOM   4382 N N   . VAL B  1 356 ? 210.877 180.380 185.850 1.00 68.26  ? 356 VAL A N   1 
ATOM   4383 C CA  . VAL B  1 356 ? 212.134 179.998 186.487 1.00 68.56  ? 356 VAL A CA  1 
ATOM   4384 C C   . VAL B  1 356 ? 212.706 181.161 187.288 1.00 74.30  ? 356 VAL A C   1 
ATOM   4385 O O   . VAL B  1 356 ? 213.132 180.992 188.437 1.00 74.71  ? 356 VAL A O   1 
ATOM   4386 C CB  . VAL B  1 356 ? 213.132 179.486 185.432 1.00 72.11  ? 356 VAL A CB  1 
ATOM   4387 C CG1 . VAL B  1 356 ? 214.564 179.689 185.904 1.00 74.57  ? 356 VAL A CG1 1 
ATOM   4388 C CG2 . VAL B  1 356 ? 212.871 178.021 185.126 1.00 70.69  ? 356 VAL A CG2 1 
ATOM   4389 N N   . PHE B  1 357 ? 212.714 182.363 186.702 1.00 83.01  ? 357 PHE A N   1 
ATOM   4390 C CA  . PHE B  1 357 ? 213.257 183.529 187.395 1.00 85.51  ? 357 PHE A CA  1 
ATOM   4391 C C   . PHE B  1 357 ? 212.451 183.854 188.645 1.00 83.96  ? 357 PHE A C   1 
ATOM   4392 O O   . PHE B  1 357 ? 213.014 184.223 189.681 1.00 82.67  ? 357 PHE A O   1 
ATOM   4393 C CB  . PHE B  1 357 ? 213.291 184.729 186.450 1.00 83.09  ? 357 PHE A CB  1 
ATOM   4394 C CG  . PHE B  1 357 ? 213.632 186.025 187.128 1.00 86.76  ? 357 PHE A CG  1 
ATOM   4395 C CD1 . PHE B  1 357 ? 214.910 186.255 187.610 1.00 88.13  ? 357 PHE A CD1 1 
ATOM   4396 C CD2 . PHE B  1 357 ? 212.675 187.014 187.281 1.00 84.11  ? 357 PHE A CD2 1 
ATOM   4397 C CE1 . PHE B  1 357 ? 215.226 187.447 188.234 1.00 87.44  ? 357 PHE A CE1 1 
ATOM   4398 C CE2 . PHE B  1 357 ? 212.985 188.208 187.904 1.00 85.55  ? 357 PHE A CE2 1 
ATOM   4399 C CZ  . PHE B  1 357 ? 214.262 188.425 188.381 1.00 85.21  ? 357 PHE A CZ  1 
ATOM   4400 N N   . PHE B  1 358 ? 211.127 183.731 188.559 1.00 73.96  ? 358 PHE A N   1 
ATOM   4401 C CA  . PHE B  1 358 ? 210.269 183.930 189.716 1.00 70.26  ? 358 PHE A CA  1 
ATOM   4402 C C   . PHE B  1 358 ? 210.569 182.903 190.792 1.00 67.11  ? 358 PHE A C   1 
ATOM   4403 O O   . PHE B  1 358 ? 210.565 183.228 191.980 1.00 69.42  ? 358 PHE A O   1 
ATOM   4404 C CB  . PHE B  1 358 ? 208.801 183.860 189.287 1.00 70.75  ? 358 PHE A CB  1 
ATOM   4405 C CG  . PHE B  1 358 ? 207.823 183.852 190.429 1.00 73.26  ? 358 PHE A CG  1 
ATOM   4406 C CD1 . PHE B  1 358 ? 207.389 182.659 190.982 1.00 72.02  ? 358 PHE A CD1 1 
ATOM   4407 C CD2 . PHE B  1 358 ? 207.320 185.038 190.934 1.00 75.13  ? 358 PHE A CD2 1 
ATOM   4408 C CE1 . PHE B  1 358 ? 206.487 182.650 192.025 1.00 72.70  ? 358 PHE A CE1 1 
ATOM   4409 C CE2 . PHE B  1 358 ? 206.415 185.034 191.977 1.00 74.15  ? 358 PHE A CE2 1 
ATOM   4410 C CZ  . PHE B  1 358 ? 205.998 183.839 192.523 1.00 72.18  ? 358 PHE A CZ  1 
ATOM   4411 N N   . LEU B  1 359 ? 210.825 181.655 190.394 1.00 68.24  ? 359 LEU A N   1 
ATOM   4412 C CA  . LEU B  1 359 ? 211.169 180.631 191.375 1.00 72.79  ? 359 LEU A CA  1 
ATOM   4413 C C   . LEU B  1 359 ? 212.563 180.856 191.952 1.00 73.63  ? 359 LEU A C   1 
ATOM   4414 O O   . LEU B  1 359 ? 212.801 180.586 193.133 1.00 71.12  ? 359 LEU A O   1 
ATOM   4415 C CB  . LEU B  1 359 ? 211.067 179.243 190.745 1.00 68.63  ? 359 LEU A CB  1 
ATOM   4416 C CG  . LEU B  1 359 ? 211.261 178.068 191.703 1.00 64.82  ? 359 LEU A CG  1 
ATOM   4417 C CD1 . LEU B  1 359 ? 210.258 178.145 192.839 1.00 70.02  ? 359 LEU A CD1 1 
ATOM   4418 C CD2 . LEU B  1 359 ? 211.146 176.743 190.971 1.00 66.72  ? 359 LEU A CD2 1 
ATOM   4419 N N   . ILE B  1 360 ? 213.496 181.350 191.139 1.00 72.19  ? 360 ILE A N   1 
ATOM   4420 C CA  . ILE B  1 360 ? 214.882 181.518 191.562 1.00 67.71  ? 360 ILE A CA  1 
ATOM   4421 C C   . ILE B  1 360 ? 215.193 182.966 191.940 1.00 72.30  ? 360 ILE A C   1 
ATOM   4422 O O   . ILE B  1 360 ? 216.364 183.329 192.091 1.00 74.97  ? 360 ILE A O   1 
ATOM   4423 C CB  . ILE B  1 360 ? 215.846 180.996 190.478 1.00 70.48  ? 360 ILE A CB  1 
ATOM   4424 C CG1 . ILE B  1 360 ? 217.189 180.585 191.089 1.00 74.21  ? 360 ILE A CG1 1 
ATOM   4425 C CG2 . ILE B  1 360 ? 216.026 182.018 189.358 1.00 72.50  ? 360 ILE A CG2 1 
ATOM   4426 C CD1 . ILE B  1 360 ? 217.943 179.559 190.272 1.00 72.71  ? 360 ILE A CD1 1 
ATOM   4427 N N   . ASN B  1 361 ? 214.170 183.790 192.132 1.00 82.81  ? 361 ASN A N   1 
ATOM   4428 C CA  . ASN B  1 361 ? 214.366 185.199 192.453 1.00 81.76  ? 361 ASN A CA  1 
ATOM   4429 C C   . ASN B  1 361 ? 215.112 185.340 193.776 1.00 85.58  ? 361 ASN A C   1 
ATOM   4430 O O   . ASN B  1 361 ? 214.639 184.830 194.803 1.00 87.15  ? 361 ASN A O   1 
ATOM   4431 C CB  . ASN B  1 361 ? 213.013 185.906 192.525 1.00 80.08  ? 361 ASN A CB  1 
ATOM   4432 C CG  . ASN B  1 361 ? 213.134 187.419 192.532 1.00 85.02  ? 361 ASN A CG  1 
ATOM   4433 O OD1 . ASN B  1 361 ? 214.110 187.979 193.030 1.00 86.38  ? 361 ASN A OD1 1 
ATOM   4434 N ND2 . ASN B  1 361 ? 212.134 188.090 191.974 1.00 85.59  ? 361 ASN A ND2 1 
ATOM   4435 N N   . PRO B  1 362 ? 216.267 186.011 193.802 1.00 84.21  ? 362 PRO A N   1 
ATOM   4436 C CA  . PRO B  1 362 ? 217.015 186.147 195.058 1.00 83.45  ? 362 PRO A CA  1 
ATOM   4437 C C   . PRO B  1 362 ? 216.472 187.242 195.963 1.00 86.32  ? 362 PRO A C   1 
ATOM   4438 O O   . PRO B  1 362 ? 216.536 187.125 197.191 1.00 83.79  ? 362 PRO A O   1 
ATOM   4439 C CB  . PRO B  1 362 ? 218.435 186.467 194.578 1.00 83.86  ? 362 PRO A CB  1 
ATOM   4440 C CG  . PRO B  1 362 ? 218.229 187.177 193.287 1.00 83.65  ? 362 PRO A CG  1 
ATOM   4441 C CD  . PRO B  1 362 ? 216.998 186.578 192.655 1.00 82.01  ? 362 PRO A CD  1 
ATOM   4442 N N   . THR B  1 363 ? 215.943 188.309 195.369 1.00 85.54  ? 363 THR A N   1 
ATOM   4443 C CA  . THR B  1 363 ? 215.451 189.438 196.148 1.00 83.27  ? 363 THR A CA  1 
ATOM   4444 C C   . THR B  1 363 ? 214.239 189.026 196.972 1.00 82.95  ? 363 THR A C   1 
ATOM   4445 O O   . THR B  1 363 ? 213.298 188.419 196.453 1.00 88.17  ? 363 THR A O   1 
ATOM   4446 C CB  . THR B  1 363 ? 215.090 190.600 195.227 1.00 82.97  ? 363 THR A CB  1 
ATOM   4447 O OG1 . THR B  1 363 ? 214.080 190.179 194.303 1.00 88.16  ? 363 THR A OG1 1 
ATOM   4448 C CG2 . THR B  1 363 ? 216.313 191.064 194.456 1.00 83.25  ? 363 THR A CG2 1 
ATOM   4449 N N   . LYS B  1 364 ? 214.255 189.372 198.260 1.00 82.85  ? 364 LYS A N   1 
ATOM   4450 C CA  . LYS B  1 364 ? 213.208 188.957 199.193 1.00 86.15  ? 364 LYS A CA  1 
ATOM   4451 C C   . LYS B  1 364 ? 211.959 189.812 198.973 1.00 82.37  ? 364 LYS A C   1 
ATOM   4452 O O   . LYS B  1 364 ? 211.577 190.649 199.793 1.00 88.31  ? 364 LYS A O   1 
ATOM   4453 C CB  . LYS B  1 364 ? 213.700 189.056 200.630 1.00 86.65  ? 364 LYS A CB  1 
ATOM   4454 C CG  . LYS B  1 364 ? 214.834 188.104 200.986 1.00 85.48  ? 364 LYS A CG  1 
ATOM   4455 C CD  . LYS B  1 364 ? 216.196 188.733 200.728 1.00 86.57  ? 364 LYS A CD  1 
ATOM   4456 C CE  . LYS B  1 364 ? 217.324 187.819 201.178 1.00 86.77  ? 364 LYS A CE  1 
ATOM   4457 N NZ  . LYS B  1 364 ? 218.660 188.431 200.940 1.00 86.35  ? 364 LYS A NZ  1 
ATOM   4458 N N   . THR B  1 365 ? 211.311 189.582 197.832 1.00 79.20  ? 365 THR A N   1 
ATOM   4459 C CA  . THR B  1 365 ? 210.147 190.365 197.439 1.00 87.57  ? 365 THR A CA  1 
ATOM   4460 C C   . THR B  1 365 ? 208.870 189.537 197.384 1.00 88.12  ? 365 THR A C   1 
ATOM   4461 O O   . THR B  1 365 ? 207.891 189.869 198.059 1.00 89.74  ? 365 THR A O   1 
ATOM   4462 C CB  . THR B  1 365 ? 210.404 191.029 196.081 1.00 90.83  ? 365 THR A CB  1 
ATOM   4463 O OG1 . THR B  1 365 ? 210.859 190.044 195.146 1.00 87.19  ? 365 THR A OG1 1 
ATOM   4464 C CG2 . THR B  1 365 ? 211.454 192.119 196.215 1.00 88.61  ? 365 THR A CG2 1 
ATOM   4465 N N   . PHE B  1 366 ? 208.849 188.462 196.599 1.00 81.78  ? 366 PHE A N   1 
ATOM   4466 C CA  . PHE B  1 366 ? 207.634 187.682 196.352 1.00 80.57  ? 366 PHE A CA  1 
ATOM   4467 C C   . PHE B  1 366 ? 207.778 186.307 196.998 1.00 80.84  ? 366 PHE A C   1 
ATOM   4468 O O   . PHE B  1 366 ? 208.458 185.430 196.456 1.00 79.36  ? 366 PHE A O   1 
ATOM   4469 C CB  . PHE B  1 366 ? 207.354 187.554 194.854 1.00 76.25  ? 366 PHE A CB  1 
ATOM   4470 C CG  . PHE B  1 366 ? 206.896 188.832 194.197 1.00 78.78  ? 366 PHE A CG  1 
ATOM   4471 C CD1 . PHE B  1 366 ? 206.880 190.031 194.889 1.00 78.59  ? 366 PHE A CD1 1 
ATOM   4472 C CD2 . PHE B  1 366 ? 206.483 188.826 192.876 1.00 80.99  ? 366 PHE A CD2 1 
ATOM   4473 C CE1 . PHE B  1 366 ? 206.459 191.197 194.277 1.00 79.77  ? 366 PHE A CE1 1 
ATOM   4474 C CE2 . PHE B  1 366 ? 206.061 189.989 192.259 1.00 75.88  ? 366 PHE A CE2 1 
ATOM   4475 C CZ  . PHE B  1 366 ? 206.049 191.175 192.961 1.00 76.62  ? 366 PHE A CZ  1 
ATOM   4476 N N   . TYR B  1 367 ? 207.126 186.122 198.148 1.00 78.63  ? 367 TYR A N   1 
ATOM   4477 C CA  . TYR B  1 367 ? 207.056 184.825 198.823 1.00 74.57  ? 367 TYR A CA  1 
ATOM   4478 C C   . TYR B  1 367 ? 208.448 184.256 199.092 1.00 77.76  ? 367 TYR A C   1 
ATOM   4479 O O   . TYR B  1 367 ? 208.712 183.075 198.866 1.00 83.41  ? 367 TYR A O   1 
ATOM   4480 C CB  . TYR B  1 367 ? 206.217 183.837 198.010 1.00 74.26  ? 367 TYR A CB  1 
ATOM   4481 C CG  . TYR B  1 367 ? 204.745 184.153 197.989 1.00 79.88  ? 367 TYR A CG  1 
ATOM   4482 C CD1 . TYR B  1 367 ? 203.950 183.905 199.096 1.00 82.00  ? 367 TYR A CD1 1 
ATOM   4483 C CD2 . TYR B  1 367 ? 204.149 184.697 196.860 1.00 76.90  ? 367 TYR A CD2 1 
ATOM   4484 C CE1 . TYR B  1 367 ? 202.604 184.191 199.083 1.00 80.58  ? 367 TYR A CE1 1 
ATOM   4485 C CE2 . TYR B  1 367 ? 202.801 184.986 196.838 1.00 75.83  ? 367 TYR A CE2 1 
ATOM   4486 C CZ  . TYR B  1 367 ? 202.034 184.730 197.952 1.00 80.96  ? 367 TYR A CZ  1 
ATOM   4487 O OH  . TYR B  1 367 ? 200.690 185.015 197.941 1.00 84.98  ? 367 TYR A OH  1 
ATOM   4488 N N   . TYR B  1 368 ? 209.343 185.110 199.591 1.00 83.41  ? 368 TYR A N   1 
ATOM   4489 C CA  . TYR B  1 368 ? 210.750 184.731 199.673 1.00 79.87  ? 368 TYR A CA  1 
ATOM   4490 C C   . TYR B  1 368 ? 210.967 183.543 200.603 1.00 80.73  ? 368 TYR A C   1 
ATOM   4491 O O   . TYR B  1 368 ? 211.740 182.635 200.281 1.00 86.93  ? 368 TYR A O   1 
ATOM   4492 C CB  . TYR B  1 368 ? 211.594 185.931 200.104 1.00 86.20  ? 368 TYR A CB  1 
ATOM   4493 C CG  . TYR B  1 368 ? 211.426 186.360 201.544 1.00 88.79  ? 368 TYR A CG  1 
ATOM   4494 C CD1 . TYR B  1 368 ? 210.355 187.153 201.930 1.00 85.60  ? 368 TYR A CD1 1 
ATOM   4495 C CD2 . TYR B  1 368 ? 212.352 185.995 202.509 1.00 86.82  ? 368 TYR A CD2 1 
ATOM   4496 C CE1 . TYR B  1 368 ? 210.201 187.556 203.242 1.00 86.53  ? 368 TYR A CE1 1 
ATOM   4497 C CE2 . TYR B  1 368 ? 212.209 186.395 203.822 1.00 85.72  ? 368 TYR A CE2 1 
ATOM   4498 C CZ  . TYR B  1 368 ? 211.131 187.174 204.183 1.00 85.82  ? 368 TYR A CZ  1 
ATOM   4499 O OH  . TYR B  1 368 ? 210.983 187.573 205.491 1.00 84.09  ? 368 TYR A OH  1 
ATOM   4500 N N   . LYS B  1 369 ? 210.290 183.516 201.752 1.00 75.81  ? 369 LYS A N   1 
ATOM   4501 C CA  . LYS B  1 369 ? 210.483 182.409 202.684 1.00 79.74  ? 369 LYS A CA  1 
ATOM   4502 C C   . LYS B  1 369 ? 210.046 181.086 202.065 1.00 79.72  ? 369 LYS A C   1 
ATOM   4503 O O   . LYS B  1 369 ? 210.815 180.116 202.029 1.00 78.64  ? 369 LYS A O   1 
ATOM   4504 C CB  . LYS B  1 369 ? 209.715 182.676 203.979 1.00 79.61  ? 369 LYS A CB  1 
ATOM   4505 C CG  . LYS B  1 369 ? 210.399 183.653 204.915 1.00 82.79  ? 369 LYS A CG  1 
ATOM   4506 C CD  . LYS B  1 369 ? 209.797 183.603 206.308 1.00 82.72  ? 369 LYS A CD  1 
ATOM   4507 C CE  . LYS B  1 369 ? 210.695 184.292 207.320 1.00 81.27  ? 369 LYS A CE  1 
ATOM   4508 N NZ  . LYS B  1 369 ? 210.312 183.959 208.719 1.00 83.64  ? 369 LYS A NZ  1 
ATOM   4509 N N   . SER B  1 370 ? 208.814 181.040 201.554 1.00 77.33  ? 370 SER A N   1 
ATOM   4510 C CA  . SER B  1 370 ? 208.297 179.813 200.959 1.00 71.90  ? 370 SER A CA  1 
ATOM   4511 C C   . SER B  1 370 ? 209.074 179.436 199.708 1.00 70.57  ? 370 SER A C   1 
ATOM   4512 O O   . SER B  1 370 ? 209.338 178.254 199.466 1.00 84.00  ? 370 SER A O   1 
ATOM   4513 C CB  . SER B  1 370 ? 206.813 179.975 200.643 1.00 71.98  ? 370 SER A CB  1 
ATOM   4514 O OG  . SER B  1 370 ? 206.118 180.513 201.752 1.00 77.07  ? 370 SER A OG  1 
ATOM   4515 N N   . ARG B  1 371 ? 209.443 180.426 198.898 1.00 60.10  ? 371 ARG A N   1 
ATOM   4516 C CA  . ARG B  1 371 ? 210.206 180.147 197.689 1.00 63.27  ? 371 ARG A CA  1 
ATOM   4517 C C   . ARG B  1 371 ? 211.565 179.542 198.012 1.00 66.34  ? 371 ARG A C   1 
ATOM   4518 O O   . ARG B  1 371 ? 211.993 178.578 197.369 1.00 70.43  ? 371 ARG A O   1 
ATOM   4519 C CB  . ARG B  1 371 ? 210.374 181.430 196.887 1.00 72.08  ? 371 ARG A CB  1 
ATOM   4520 C CG  . ARG B  1 371 ? 210.343 181.248 195.408 1.00 65.20  ? 371 ARG A CG  1 
ATOM   4521 C CD  . ARG B  1 371 ? 210.906 182.478 194.747 1.00 68.92  ? 371 ARG A CD  1 
ATOM   4522 N NE  . ARG B  1 371 ? 210.510 183.716 195.407 1.00 67.64  ? 371 ARG A NE  1 
ATOM   4523 C CZ  . ARG B  1 371 ? 211.355 184.563 195.979 1.00 68.86  ? 371 ARG A CZ  1 
ATOM   4524 N NH1 . ARG B  1 371 ? 212.657 184.331 196.001 1.00 67.85  ? 371 ARG A NH1 1 
ATOM   4525 N NH2 . ARG B  1 371 ? 210.882 185.672 196.538 1.00 72.21  ? 371 ARG A NH2 1 
ATOM   4526 N N   . PHE B  1 372 ? 212.263 180.095 199.005 1.00 70.38  ? 372 PHE A N   1 
ATOM   4527 C CA  . PHE B  1 372 ? 213.570 179.557 199.365 1.00 69.80  ? 372 PHE A CA  1 
ATOM   4528 C C   . PHE B  1 372 ? 213.440 178.175 199.990 1.00 75.07  ? 372 PHE A C   1 
ATOM   4529 O O   . PHE B  1 372 ? 214.281 177.300 199.752 1.00 75.73  ? 372 PHE A O   1 
ATOM   4530 C CB  . PHE B  1 372 ? 214.294 180.520 200.304 1.00 72.77  ? 372 PHE A CB  1 
ATOM   4531 C CG  . PHE B  1 372 ? 214.655 181.830 199.664 1.00 76.84  ? 372 PHE A CG  1 
ATOM   4532 C CD1 . PHE B  1 372 ? 214.872 181.912 198.299 1.00 71.18  ? 372 PHE A CD1 1 
ATOM   4533 C CD2 . PHE B  1 372 ? 214.774 182.980 200.426 1.00 79.13  ? 372 PHE A CD2 1 
ATOM   4534 C CE1 . PHE B  1 372 ? 215.200 183.116 197.706 1.00 75.91  ? 372 PHE A CE1 1 
ATOM   4535 C CE2 . PHE B  1 372 ? 215.102 184.187 199.838 1.00 78.50  ? 372 PHE A CE2 1 
ATOM   4536 C CZ  . PHE B  1 372 ? 215.316 184.254 198.477 1.00 78.68  ? 372 PHE A CZ  1 
ATOM   4537 N N   . TRP B  1 373 ? 212.390 177.955 200.786 1.00 66.02  ? 373 TRP A N   1 
ATOM   4538 C CA  . TRP B  1 373 ? 212.148 176.620 201.323 1.00 60.17  ? 373 TRP A CA  1 
ATOM   4539 C C   . TRP B  1 373 ? 211.902 175.613 200.206 1.00 54.89  ? 373 TRP A C   1 
ATOM   4540 O O   . TRP B  1 373 ? 212.426 174.492 200.240 1.00 61.88  ? 373 TRP A O   1 
ATOM   4541 C CB  . TRP B  1 373 ? 210.968 176.654 202.291 1.00 57.40  ? 373 TRP A CB  1 
ATOM   4542 C CG  . TRP B  1 373 ? 210.520 175.306 202.744 1.00 55.24  ? 373 TRP A CG  1 
ATOM   4543 C CD1 . TRP B  1 373 ? 210.936 174.637 203.855 1.00 60.96  ? 373 TRP A CD1 1 
ATOM   4544 C CD2 . TRP B  1 373 ? 209.555 174.465 202.106 1.00 61.51  ? 373 TRP A CD2 1 
ATOM   4545 N NE1 . TRP B  1 373 ? 210.296 173.426 203.944 1.00 66.89  ? 373 TRP A NE1 1 
ATOM   4546 C CE2 . TRP B  1 373 ? 209.441 173.298 202.882 1.00 65.76  ? 373 TRP A CE2 1 
ATOM   4547 C CE3 . TRP B  1 373 ? 208.779 174.584 200.951 1.00 60.55  ? 373 TRP A CE3 1 
ATOM   4548 C CZ2 . TRP B  1 373 ? 208.583 172.257 202.541 1.00 64.38  ? 373 TRP A CZ2 1 
ATOM   4549 C CZ3 . TRP B  1 373 ? 207.930 173.551 200.614 1.00 65.33  ? 373 TRP A CZ3 1 
ATOM   4550 C CH2 . TRP B  1 373 ? 207.837 172.404 201.406 1.00 65.83  ? 373 TRP A CH2 1 
ATOM   4551 N N   . LEU B  1 374 ? 211.115 175.998 199.199 1.00 49.02  ? 374 LEU A N   1 
ATOM   4552 C CA  . LEU B  1 374 ? 210.876 175.113 198.066 1.00 46.54  ? 374 LEU A CA  1 
ATOM   4553 C C   . LEU B  1 374 ? 212.153 174.869 197.276 1.00 52.80  ? 374 LEU A C   1 
ATOM   4554 O O   . LEU B  1 374 ? 212.353 173.769 196.754 1.00 58.06  ? 374 LEU A O   1 
ATOM   4555 C CB  . LEU B  1 374 ? 209.783 175.695 197.168 1.00 41.82  ? 374 LEU A CB  1 
ATOM   4556 C CG  . LEU B  1 374 ? 209.197 174.837 196.041 1.00 42.48  ? 374 LEU A CG  1 
ATOM   4557 C CD1 . LEU B  1 374 ? 209.987 174.969 194.748 1.00 51.10  ? 374 LEU A CD1 1 
ATOM   4558 C CD2 . LEU B  1 374 ? 209.106 173.383 196.466 1.00 52.46  ? 374 LEU A CD2 1 
ATOM   4559 N N   . LEU B  1 375 ? 213.022 175.876 197.169 1.00 49.57  ? 375 LEU A N   1 
ATOM   4560 C CA  . LEU B  1 375 ? 214.298 175.673 196.489 1.00 42.26  ? 375 LEU A CA  1 
ATOM   4561 C C   . LEU B  1 375 ? 215.173 174.677 197.239 1.00 53.11  ? 375 LEU A C   1 
ATOM   4562 O O   . LEU B  1 375 ? 215.782 173.793 196.624 1.00 65.07  ? 375 LEU A O   1 
ATOM   4563 C CB  . LEU B  1 375 ? 215.026 177.004 196.324 1.00 54.73  ? 375 LEU A CB  1 
ATOM   4564 C CG  . LEU B  1 375 ? 214.949 177.589 194.917 1.00 64.64  ? 375 LEU A CG  1 
ATOM   4565 C CD1 . LEU B  1 375 ? 215.546 176.626 193.904 1.00 58.13  ? 375 LEU A CD1 1 
ATOM   4566 C CD2 . LEU B  1 375 ? 213.510 177.892 194.574 1.00 64.75  ? 375 LEU A CD2 1 
ATOM   4567 N N   . LYS B  1 376 ? 215.243 174.800 198.566 1.00 56.88  ? 376 LYS A N   1 
ATOM   4568 C CA  . LYS B  1 376 ? 215.994 173.823 199.349 1.00 61.46  ? 376 LYS A CA  1 
ATOM   4569 C C   . LYS B  1 376 ? 215.412 172.427 199.177 1.00 66.98  ? 376 LYS A C   1 
ATOM   4570 O O   . LYS B  1 376 ? 216.155 171.447 199.039 1.00 64.58  ? 376 LYS A O   1 
ATOM   4571 C CB  . LYS B  1 376 ? 216.012 174.209 200.828 1.00 60.63  ? 376 LYS A CB  1 
ATOM   4572 C CG  . LYS B  1 376 ? 216.444 175.634 201.111 1.00 62.25  ? 376 LYS A CG  1 
ATOM   4573 C CD  . LYS B  1 376 ? 217.873 175.889 200.674 1.00 69.78  ? 376 LYS A CD  1 
ATOM   4574 C CE  . LYS B  1 376 ? 218.273 177.329 200.948 1.00 67.56  ? 376 LYS A CE  1 
ATOM   4575 N NZ  . LYS B  1 376 ? 219.419 177.752 200.099 1.00 66.21  ? 376 LYS A NZ  1 
ATOM   4576 N N   . LEU B  1 377 ? 214.082 172.317 199.183 1.00 61.97  ? 377 LEU A N   1 
ATOM   4577 C CA  . LEU B  1 377 ? 213.448 171.012 199.025 1.00 45.07  ? 377 LEU A CA  1 
ATOM   4578 C C   . LEU B  1 377 ? 213.731 170.411 197.655 1.00 48.69  ? 377 LEU A C   1 
ATOM   4579 O O   . LEU B  1 377 ? 213.993 169.210 197.541 1.00 64.22  ? 377 LEU A O   1 
ATOM   4580 C CB  . LEU B  1 377 ? 211.946 171.124 199.253 1.00 47.45  ? 377 LEU A CB  1 
ATOM   4581 C CG  . LEU B  1 377 ? 211.357 169.831 199.797 1.00 54.12  ? 377 LEU A CG  1 
ATOM   4582 C CD1 . LEU B  1 377 ? 212.019 169.511 201.121 1.00 55.86  ? 377 LEU A CD1 1 
ATOM   4583 C CD2 . LEU B  1 377 ? 209.853 169.945 199.945 1.00 52.48  ? 377 LEU A CD2 1 
ATOM   4584 N N   . LEU B  1 378 ? 213.664 171.224 196.600 1.00 39.89  ? 378 LEU A N   1 
ATOM   4585 C CA  . LEU B  1 378 ? 213.959 170.722 195.262 1.00 39.88  ? 378 LEU A CA  1 
ATOM   4586 C C   . LEU B  1 378 ? 215.412 170.282 195.153 1.00 50.54  ? 378 LEU A C   1 
ATOM   4587 O O   . LEU B  1 378 ? 215.716 169.258 194.528 1.00 60.05  ? 378 LEU A O   1 
ATOM   4588 C CB  . LEU B  1 378 ? 213.640 171.788 194.216 1.00 43.32  ? 378 LEU A CB  1 
ATOM   4589 C CG  . LEU B  1 378 ? 212.222 171.781 193.646 1.00 49.40  ? 378 LEU A CG  1 
ATOM   4590 C CD1 . LEU B  1 378 ? 212.122 172.732 192.468 1.00 57.81  ? 378 LEU A CD1 1 
ATOM   4591 C CD2 . LEU B  1 378 ? 211.819 170.378 193.234 1.00 50.59  ? 378 LEU A CD2 1 
ATOM   4592 N N   . PHE B  1 379 ? 216.326 171.045 195.757 1.00 49.95  ? 379 PHE A N   1 
ATOM   4593 C CA  . PHE B  1 379 ? 217.727 170.640 195.767 1.00 52.69  ? 379 PHE A CA  1 
ATOM   4594 C C   . PHE B  1 379 ? 217.910 169.315 196.493 1.00 53.79  ? 379 PHE A C   1 
ATOM   4595 O O   . PHE B  1 379 ? 218.656 168.443 196.033 1.00 58.62  ? 379 PHE A O   1 
ATOM   4596 C CB  . PHE B  1 379 ? 218.582 171.729 196.411 1.00 54.92  ? 379 PHE A CB  1 
ATOM   4597 C CG  . PHE B  1 379 ? 219.981 171.293 196.725 1.00 57.74  ? 379 PHE A CG  1 
ATOM   4598 C CD1 . PHE B  1 379 ? 220.881 171.030 195.709 1.00 51.86  ? 379 PHE A CD1 1 
ATOM   4599 C CD2 . PHE B  1 379 ? 220.395 171.146 198.037 1.00 59.29  ? 379 PHE A CD2 1 
ATOM   4600 C CE1 . PHE B  1 379 ? 222.167 170.628 195.994 1.00 55.62  ? 379 PHE A CE1 1 
ATOM   4601 C CE2 . PHE B  1 379 ? 221.680 170.744 198.329 1.00 56.57  ? 379 PHE A CE2 1 
ATOM   4602 C CZ  . PHE B  1 379 ? 222.568 170.485 197.306 1.00 58.42  ? 379 PHE A CZ  1 
ATOM   4603 N N   . ARG B  1 380 ? 217.232 169.141 197.629 1.00 46.41  ? 380 ARG A N   1 
ATOM   4604 C CA  . ARG B  1 380 ? 217.361 167.896 198.379 1.00 52.19  ? 380 ARG A CA  1 
ATOM   4605 C C   . ARG B  1 380 ? 216.745 166.724 197.623 1.00 54.72  ? 380 ARG A C   1 
ATOM   4606 O O   . ARG B  1 380 ? 217.233 165.593 197.720 1.00 57.62  ? 380 ARG A O   1 
ATOM   4607 C CB  . ARG B  1 380 ? 216.720 168.045 199.759 1.00 45.26  ? 380 ARG A CB  1 
ATOM   4608 C CG  . ARG B  1 380 ? 217.654 168.633 200.802 1.00 47.17  ? 380 ARG A CG  1 
ATOM   4609 C CD  . ARG B  1 380 ? 216.993 168.743 202.163 1.00 51.03  ? 380 ARG A CD  1 
ATOM   4610 N NE  . ARG B  1 380 ? 216.172 167.580 202.477 1.00 54.88  ? 380 ARG A NE  1 
ATOM   4611 C CZ  . ARG B  1 380 ? 214.989 167.639 203.073 1.00 63.22  ? 380 ARG A CZ  1 
ATOM   4612 N NH1 . ARG B  1 380 ? 214.449 168.794 203.425 1.00 65.00  ? 380 ARG A NH1 1 
ATOM   4613 N NH2 . ARG B  1 380 ? 214.331 166.510 203.323 1.00 54.93  ? 380 ARG A NH2 1 
ATOM   4614 N N   . VAL B  1 381 ? 215.673 166.972 196.869 1.00 49.93  ? 381 VAL A N   1 
ATOM   4615 C CA  . VAL B  1 381 ? 214.991 165.878 196.186 1.00 37.60  ? 381 VAL A CA  1 
ATOM   4616 C C   . VAL B  1 381 ? 215.721 165.492 194.906 1.00 42.76  ? 381 VAL A C   1 
ATOM   4617 O O   . VAL B  1 381 ? 215.633 164.341 194.463 1.00 60.78  ? 381 VAL A O   1 
ATOM   4618 C CB  . VAL B  1 381 ? 213.518 166.243 195.919 1.00 38.48  ? 381 VAL A CB  1 
ATOM   4619 C CG1 . VAL B  1 381 ? 213.368 167.026 194.630 1.00 49.49  ? 381 VAL A CG1 1 
ATOM   4620 C CG2 . VAL B  1 381 ? 212.666 164.995 195.883 1.00 43.39  ? 381 VAL A CG2 1 
ATOM   4621 N N   . PHE B  1 382 ? 216.450 166.424 194.288 1.00 42.23  ? 382 PHE A N   1 
ATOM   4622 C CA  . PHE B  1 382 ? 217.229 166.072 193.107 1.00 52.49  ? 382 PHE A CA  1 
ATOM   4623 C C   . PHE B  1 382 ? 218.619 165.557 193.452 1.00 58.84  ? 382 PHE A C   1 
ATOM   4624 O O   . PHE B  1 382 ? 219.366 165.173 192.546 1.00 59.83  ? 382 PHE A O   1 
ATOM   4625 C CB  . PHE B  1 382 ? 217.336 167.270 192.162 1.00 50.45  ? 382 PHE A CB  1 
ATOM   4626 C CG  . PHE B  1 382 ? 216.240 167.328 191.139 1.00 50.75  ? 382 PHE A CG  1 
ATOM   4627 C CD1 . PHE B  1 382 ? 214.943 167.628 191.512 1.00 52.52  ? 382 PHE A CD1 1 
ATOM   4628 C CD2 . PHE B  1 382 ? 216.504 167.070 189.806 1.00 56.90  ? 382 PHE A CD2 1 
ATOM   4629 C CE1 . PHE B  1 382 ? 213.933 167.679 190.575 1.00 51.01  ? 382 PHE A CE1 1 
ATOM   4630 C CE2 . PHE B  1 382 ? 215.497 167.119 188.864 1.00 56.20  ? 382 PHE A CE2 1 
ATOM   4631 C CZ  . PHE B  1 382 ? 214.210 167.424 189.250 1.00 55.75  ? 382 PHE A CZ  1 
ATOM   4632 N N   . THR B  1 383 ? 218.975 165.539 194.734 1.00 61.11  ? 383 THR A N   1 
ATOM   4633 C CA  . THR B  1 383 ? 220.213 164.945 195.219 1.00 61.30  ? 383 THR A CA  1 
ATOM   4634 C C   . THR B  1 383 ? 219.851 163.933 196.295 1.00 64.90  ? 383 THR A C   1 
ATOM   4635 O O   . THR B  1 383 ? 220.396 163.958 197.403 1.00 60.19  ? 383 THR A O   1 
ATOM   4636 C CB  . THR B  1 383 ? 221.160 166.012 195.763 1.00 60.30  ? 383 THR A CB  1 
ATOM   4637 O OG1 . THR B  1 383 ? 220.435 166.892 196.628 1.00 54.36  ? 383 THR A OG1 1 
ATOM   4638 C CG2 . THR B  1 383 ? 221.761 166.816 194.623 1.00 60.31  ? 383 THR A CG2 1 
ATOM   4639 N N   . ALA B  1 384 ? 218.907 163.053 195.960 1.00 67.22  ? 384 ALA A N   1 
ATOM   4640 C CA  . ALA B  1 384 ? 218.209 162.250 196.961 1.00 68.18  ? 384 ALA A CA  1 
ATOM   4641 C C   . ALA B  1 384 ? 219.112 161.368 197.815 1.00 73.38  ? 384 ALA A C   1 
ATOM   4642 O O   . ALA B  1 384 ? 218.971 161.403 199.049 1.00 79.04  ? 384 ALA A O   1 
ATOM   4643 C CB  . ALA B  1 384 ? 217.134 161.414 196.261 1.00 64.36  ? 384 ALA A CB  1 
ATOM   4644 N N   . PRO B  1 385 ? 220.025 160.560 197.261 1.00 62.96  ? 385 PRO A N   1 
ATOM   4645 C CA  . PRO B  1 385 ? 220.728 159.585 198.115 1.00 53.28  ? 385 PRO A CA  1 
ATOM   4646 C C   . PRO B  1 385 ? 221.544 160.208 199.233 1.00 58.47  ? 385 PRO A C   1 
ATOM   4647 O O   . PRO B  1 385 ? 221.670 159.601 200.303 1.00 59.98  ? 385 PRO A O   1 
ATOM   4648 C CB  . PRO B  1 385 ? 221.625 158.831 197.123 1.00 59.52  ? 385 PRO A CB  1 
ATOM   4649 C CG  . PRO B  1 385 ? 221.765 159.740 195.963 1.00 61.36  ? 385 PRO A CG  1 
ATOM   4650 C CD  . PRO B  1 385 ? 220.470 160.468 195.859 1.00 58.97  ? 385 PRO A CD  1 
ATOM   4651 N N   . PHE B  1 386 ? 222.091 161.403 199.030 1.00 62.73  ? 386 PHE A N   1 
ATOM   4652 C CA  . PHE B  1 386 ? 223.061 161.978 199.952 1.00 62.08  ? 386 PHE A CA  1 
ATOM   4653 C C   . PHE B  1 386 ? 222.430 162.732 201.116 1.00 63.91  ? 386 PHE A C   1 
ATOM   4654 O O   . PHE B  1 386 ? 223.164 163.214 201.985 1.00 67.13  ? 386 PHE A O   1 
ATOM   4655 C CB  . PHE B  1 386 ? 224.008 162.910 199.192 1.00 62.67  ? 386 PHE A CB  1 
ATOM   4656 C CG  . PHE B  1 386 ? 224.567 162.308 197.937 1.00 64.74  ? 386 PHE A CG  1 
ATOM   4657 C CD1 . PHE B  1 386 ? 225.283 161.124 197.982 1.00 63.10  ? 386 PHE A CD1 1 
ATOM   4658 C CD2 . PHE B  1 386 ? 224.375 162.922 196.713 1.00 63.17  ? 386 PHE A CD2 1 
ATOM   4659 C CE1 . PHE B  1 386 ? 225.797 160.566 196.830 1.00 65.27  ? 386 PHE A CE1 1 
ATOM   4660 C CE2 . PHE B  1 386 ? 224.887 162.369 195.557 1.00 63.95  ? 386 PHE A CE2 1 
ATOM   4661 C CZ  . PHE B  1 386 ? 225.599 161.189 195.616 1.00 65.47  ? 386 PHE A CZ  1 
ATOM   4662 N N   . HIS B  1 387 ? 221.106 162.845 201.167 1.00 63.62  ? 387 HIS A N   1 
ATOM   4663 C CA  . HIS B  1 387 ? 220.430 163.620 202.198 1.00 63.19  ? 387 HIS A CA  1 
ATOM   4664 C C   . HIS B  1 387 ? 219.477 162.740 202.992 1.00 59.77  ? 387 HIS A C   1 
ATOM   4665 O O   . HIS B  1 387 ? 218.755 161.916 202.423 1.00 61.89  ? 387 HIS A O   1 
ATOM   4666 C CB  . HIS B  1 387 ? 219.653 164.792 201.592 1.00 61.71  ? 387 HIS A CB  1 
ATOM   4667 C CG  . HIS B  1 387 ? 220.520 165.807 200.919 1.00 63.60  ? 387 HIS A CG  1 
ATOM   4668 N ND1 . HIS B  1 387 ? 220.891 165.710 199.595 1.00 54.64  ? 387 HIS A ND1 1 
ATOM   4669 C CD2 . HIS B  1 387 ? 221.088 166.943 201.386 1.00 62.20  ? 387 HIS A CD2 1 
ATOM   4670 C CE1 . HIS B  1 387 ? 221.652 166.741 199.278 1.00 60.83  ? 387 HIS A CE1 1 
ATOM   4671 N NE2 . HIS B  1 387 ? 221.786 167.506 200.346 1.00 62.50  ? 387 HIS A NE2 1 
ATOM   4672 N N   . LYS B  1 388 ? 219.482 162.921 204.311 1.00 63.21  ? 388 LYS A N   1 
ATOM   4673 C CA  . LYS B  1 388 ? 218.496 162.265 205.157 1.00 66.05  ? 388 LYS A CA  1 
ATOM   4674 C C   . LYS B  1 388 ? 217.102 162.720 204.754 1.00 69.46  ? 388 LYS A C   1 
ATOM   4675 O O   . LYS B  1 388 ? 216.855 163.916 204.572 1.00 72.98  ? 388 LYS A O   1 
ATOM   4676 C CB  . LYS B  1 388 ? 218.760 162.586 206.629 1.00 70.04  ? 388 LYS A CB  1 
ATOM   4677 C CG  . LYS B  1 388 ? 218.558 161.416 207.585 1.00 67.45  ? 388 LYS A CG  1 
ATOM   4678 C CD  . LYS B  1 388 ? 217.104 160.982 207.652 1.00 64.48  ? 388 LYS A CD  1 
ATOM   4679 C CE  . LYS B  1 388 ? 216.959 159.645 208.360 1.00 72.33  ? 388 LYS A CE  1 
ATOM   4680 N NZ  . LYS B  1 388 ? 215.675 158.971 208.020 1.00 72.80  ? 388 LYS A NZ  1 
ATOM   4681 N N   . VAL B  1 389 ? 216.194 161.768 204.612 1.00 61.64  ? 389 VAL A N   1 
ATOM   4682 C CA  . VAL B  1 389 ? 214.871 162.059 204.080 1.00 60.62  ? 389 VAL A CA  1 
ATOM   4683 C C   . VAL B  1 389 ? 213.971 162.590 205.187 1.00 58.42  ? 389 VAL A C   1 
ATOM   4684 O O   . VAL B  1 389 ? 214.079 162.193 206.355 1.00 62.41  ? 389 VAL A O   1 
ATOM   4685 C CB  . VAL B  1 389 ? 214.270 160.808 203.413 1.00 55.05  ? 389 VAL A CB  1 
ATOM   4686 C CG1 . VAL B  1 389 ? 213.659 159.891 204.451 1.00 56.78  ? 389 VAL A CG1 1 
ATOM   4687 C CG2 . VAL B  1 389 ? 213.238 161.205 202.376 1.00 59.50  ? 389 VAL A CG2 1 
ATOM   4688 N N   . GLY B  1 390 ? 213.107 163.535 204.822 1.00 45.27  ? 390 GLY A N   1 
ATOM   4689 C CA  . GLY B  1 390 ? 212.005 163.946 205.664 1.00 51.39  ? 390 GLY A CA  1 
ATOM   4690 C C   . GLY B  1 390 ? 210.696 163.716 204.931 1.00 52.93  ? 390 GLY A C   1 
ATOM   4691 O O   . GLY B  1 390 ? 210.676 163.209 203.808 1.00 54.72  ? 390 GLY A O   1 
ATOM   4692 N N   . PHE B  1 391 ? 209.601 164.093 205.592 1.00 44.29  ? 391 PHE A N   1 
ATOM   4693 C CA  . PHE B  1 391 ? 208.311 163.968 204.927 1.00 40.31  ? 391 PHE A CA  1 
ATOM   4694 C C   . PHE B  1 391 ? 208.212 164.910 203.739 1.00 40.43  ? 391 PHE A C   1 
ATOM   4695 O O   . PHE B  1 391 ? 207.578 164.580 202.734 1.00 47.03  ? 391 PHE A O   1 
ATOM   4696 C CB  . PHE B  1 391 ? 207.156 164.227 205.887 1.00 38.85  ? 391 PHE A CB  1 
ATOM   4697 C CG  . PHE B  1 391 ? 205.811 164.099 205.235 1.00 35.80  ? 391 PHE A CG  1 
ATOM   4698 C CD1 . PHE B  1 391 ? 205.193 165.197 204.664 1.00 35.93  ? 391 PHE A CD1 1 
ATOM   4699 C CD2 . PHE B  1 391 ? 205.187 162.871 205.150 1.00 39.37  ? 391 PHE A CD2 1 
ATOM   4700 C CE1 . PHE B  1 391 ? 203.968 165.075 204.048 1.00 36.10  ? 391 PHE A CE1 1 
ATOM   4701 C CE2 . PHE B  1 391 ? 203.963 162.746 204.534 1.00 41.35  ? 391 PHE A CE2 1 
ATOM   4702 C CZ  . PHE B  1 391 ? 203.352 163.848 203.985 1.00 41.77  ? 391 PHE A CZ  1 
ATOM   4703 N N   . ALA B  1 392 ? 208.808 166.097 203.845 1.00 37.99  ? 392 ALA A N   1 
ATOM   4704 C CA  . ALA B  1 392 ? 208.739 167.048 202.743 1.00 39.65  ? 392 ALA A CA  1 
ATOM   4705 C C   . ALA B  1 392 ? 209.428 166.501 201.499 1.00 42.19  ? 392 ALA A C   1 
ATOM   4706 O O   . ALA B  1 392 ? 208.911 166.634 200.384 1.00 41.69  ? 392 ALA A O   1 
ATOM   4707 C CB  . ALA B  1 392 ? 209.354 168.378 203.169 1.00 33.91  ? 392 ALA A CB  1 
ATOM   4708 N N   . ASP B  1 393 ? 210.589 165.866 201.675 1.00 49.71  ? 393 ASP A N   1 
ATOM   4709 C CA  . ASP B  1 393 ? 211.329 165.321 200.542 1.00 44.83  ? 393 ASP A CA  1 
ATOM   4710 C C   . ASP B  1 393 ? 210.554 164.199 199.863 1.00 45.00  ? 393 ASP A C   1 
ATOM   4711 O O   . ASP B  1 393 ? 210.396 164.190 198.637 1.00 58.43  ? 393 ASP A O   1 
ATOM   4712 C CB  . ASP B  1 393 ? 212.693 164.821 201.013 1.00 44.38  ? 393 ASP A CB  1 
ATOM   4713 C CG  . ASP B  1 393 ? 213.799 165.163 200.048 1.00 54.58  ? 393 ASP A CG  1 
ATOM   4714 O OD1 . ASP B  1 393 ? 213.511 165.852 199.050 1.00 51.75  ? 393 ASP A OD1 1 
ATOM   4715 O OD2 . ASP B  1 393 ? 214.953 164.748 200.285 1.00 64.73  ? 393 ASP A OD2 1 
ATOM   4716 N N   . PHE B  1 394 ? 210.059 163.244 200.654 1.00 38.48  ? 394 PHE A N   1 
ATOM   4717 C CA  . PHE B  1 394 ? 209.240 162.162 200.117 1.00 44.50  ? 394 PHE A CA  1 
ATOM   4718 C C   . PHE B  1 394 ? 207.998 162.697 199.418 1.00 45.92  ? 394 PHE A C   1 
ATOM   4719 O O   . PHE B  1 394 ? 207.638 162.238 198.326 1.00 49.02  ? 394 PHE A O   1 
ATOM   4720 C CB  . PHE B  1 394 ? 208.853 161.215 201.252 1.00 38.10  ? 394 PHE A CB  1 
ATOM   4721 C CG  . PHE B  1 394 ? 207.507 160.579 201.083 1.00 38.25  ? 394 PHE A CG  1 
ATOM   4722 C CD1 . PHE B  1 394 ? 207.297 159.597 200.137 1.00 45.36  ? 394 PHE A CD1 1 
ATOM   4723 C CD2 . PHE B  1 394 ? 206.447 160.970 201.879 1.00 46.43  ? 394 PHE A CD2 1 
ATOM   4724 C CE1 . PHE B  1 394 ? 206.058 159.016 199.989 1.00 50.64  ? 394 PHE A CE1 1 
ATOM   4725 C CE2 . PHE B  1 394 ? 205.206 160.395 201.734 1.00 47.18  ? 394 PHE A CE2 1 
ATOM   4726 C CZ  . PHE B  1 394 ? 205.010 159.418 200.787 1.00 49.64  ? 394 PHE A CZ  1 
ATOM   4727 N N   . TRP B  1 395 ? 207.330 163.666 200.039 1.00 40.38  ? 395 TRP A N   1 
ATOM   4728 C CA  . TRP B  1 395 ? 206.097 164.210 199.488 1.00 35.87  ? 395 TRP A CA  1 
ATOM   4729 C C   . TRP B  1 395 ? 206.352 164.887 198.148 1.00 42.39  ? 395 TRP A C   1 
ATOM   4730 O O   . TRP B  1 395 ? 205.645 164.630 197.167 1.00 56.69  ? 395 TRP A O   1 
ATOM   4731 C CB  . TRP B  1 395 ? 205.492 165.183 200.499 1.00 37.52  ? 395 TRP A CB  1 
ATOM   4732 C CG  . TRP B  1 395 ? 204.190 165.779 200.115 1.00 44.66  ? 395 TRP A CG  1 
ATOM   4733 C CD1 . TRP B  1 395 ? 202.955 165.247 200.325 1.00 43.77  ? 395 TRP A CD1 1 
ATOM   4734 C CD2 . TRP B  1 395 ? 203.983 167.043 199.481 1.00 47.07  ? 395 TRP A CD2 1 
ATOM   4735 N NE1 . TRP B  1 395 ? 201.989 166.097 199.851 1.00 51.84  ? 395 TRP A NE1 1 
ATOM   4736 C CE2 . TRP B  1 395 ? 202.595 167.211 199.334 1.00 42.43  ? 395 TRP A CE2 1 
ATOM   4737 C CE3 . TRP B  1 395 ? 204.836 168.049 199.022 1.00 47.43  ? 395 TRP A CE3 1 
ATOM   4738 C CZ2 . TRP B  1 395 ? 202.042 168.336 198.734 1.00 36.88  ? 395 TRP A CZ2 1 
ATOM   4739 C CZ3 . TRP B  1 395 ? 204.286 169.164 198.435 1.00 51.06  ? 395 TRP A CZ3 1 
ATOM   4740 C CH2 . TRP B  1 395 ? 202.902 169.299 198.294 1.00 50.08  ? 395 TRP A CH2 1 
ATOM   4741 N N   . LEU B  1 396 ? 207.385 165.731 198.077 1.00 37.47  ? 396 LEU A N   1 
ATOM   4742 C CA  . LEU B  1 396 ? 207.702 166.404 196.822 1.00 40.50  ? 396 LEU A CA  1 
ATOM   4743 C C   . LEU B  1 396 ? 208.165 165.419 195.758 1.00 43.32  ? 396 LEU A C   1 
ATOM   4744 O O   . LEU B  1 396 ? 207.875 165.612 194.572 1.00 44.61  ? 396 LEU A O   1 
ATOM   4745 C CB  . LEU B  1 396 ? 208.763 167.479 197.052 1.00 41.90  ? 396 LEU A CB  1 
ATOM   4746 C CG  . LEU B  1 396 ? 209.121 168.364 195.857 1.00 41.29  ? 396 LEU A CG  1 
ATOM   4747 C CD1 . LEU B  1 396 ? 207.873 168.807 195.112 1.00 38.38  ? 396 LEU A CD1 1 
ATOM   4748 C CD2 . LEU B  1 396 ? 209.925 169.566 196.310 1.00 48.94  ? 396 LEU A CD2 1 
ATOM   4749 N N   . ALA B  1 397 ? 208.879 164.362 196.151 1.00 38.78  ? 397 ALA A N   1 
ATOM   4750 C CA  . ALA B  1 397 ? 209.257 163.340 195.183 1.00 25.54  ? 397 ALA A CA  1 
ATOM   4751 C C   . ALA B  1 397 ? 208.030 162.648 194.608 1.00 39.81  ? 397 ALA A C   1 
ATOM   4752 O O   . ALA B  1 397 ? 207.967 162.378 193.403 1.00 51.17  ? 397 ALA A O   1 
ATOM   4753 C CB  . ALA B  1 397 ? 210.191 162.324 195.830 1.00 32.33  ? 397 ALA A CB  1 
ATOM   4754 N N   . ASP B  1 398 ? 207.039 162.352 195.452 1.00 40.89  ? 398 ASP A N   1 
ATOM   4755 C CA  . ASP B  1 398 ? 205.800 161.770 194.945 1.00 33.70  ? 398 ASP A CA  1 
ATOM   4756 C C   . ASP B  1 398 ? 205.083 162.730 194.001 1.00 42.20  ? 398 ASP A C   1 
ATOM   4757 O O   . ASP B  1 398 ? 204.568 162.317 192.953 1.00 60.45  ? 398 ASP A O   1 
ATOM   4758 C CB  . ASP B  1 398 ? 204.887 161.376 196.103 1.00 40.91  ? 398 ASP A CB  1 
ATOM   4759 C CG  . ASP B  1 398 ? 204.853 159.884 196.330 1.00 49.08  ? 398 ASP A CG  1 
ATOM   4760 O OD1 . ASP B  1 398 ? 205.155 159.134 195.382 1.00 51.58  ? 398 ASP A OD1 1 
ATOM   4761 O OD2 . ASP B  1 398 ? 204.503 159.459 197.449 1.00 53.58  ? 398 ASP A OD2 1 
ATOM   4762 N N   . GLN B  1 399 ? 205.036 164.016 194.358 1.00 32.49  ? 399 GLN A N   1 
ATOM   4763 C CA  . GLN B  1 399 ? 204.418 164.999 193.472 1.00 31.18  ? 399 GLN A CA  1 
ATOM   4764 C C   . GLN B  1 399 ? 205.120 165.038 192.124 1.00 41.25  ? 399 GLN A C   1 
ATOM   4765 O O   . GLN B  1 399 ? 204.469 165.129 191.078 1.00 42.15  ? 399 GLN A O   1 
ATOM   4766 C CB  . GLN B  1 399 ? 204.425 166.384 194.122 1.00 38.06  ? 399 GLN A CB  1 
ATOM   4767 C CG  . GLN B  1 399 ? 203.918 166.404 195.550 1.00 35.71  ? 399 GLN A CG  1 
ATOM   4768 C CD  . GLN B  1 399 ? 202.500 165.895 195.698 1.00 38.70  ? 399 GLN A CD  1 
ATOM   4769 O OE1 . GLN B  1 399 ? 201.838 165.572 194.726 1.00 46.70  ? 399 GLN A OE1 1 
ATOM   4770 N NE2 . GLN B  1 399 ? 202.055 165.760 196.930 1.00 37.66  ? 399 GLN A NE2 1 
ATOM   4771 N N   . LEU B  1 400 ? 206.451 164.966 192.130 1.00 48.32  ? 400 LEU A N   1 
ATOM   4772 C CA  . LEU B  1 400 ? 207.192 164.887 190.877 1.00 40.87  ? 400 LEU A CA  1 
ATOM   4773 C C   . LEU B  1 400 ? 206.835 163.619 190.114 1.00 40.11  ? 400 LEU A C   1 
ATOM   4774 O O   . LEU B  1 400 ? 206.737 163.631 188.882 1.00 47.59  ? 400 LEU A O   1 
ATOM   4775 C CB  . LEU B  1 400 ? 208.692 164.942 191.153 1.00 40.22  ? 400 LEU A CB  1 
ATOM   4776 C CG  . LEU B  1 400 ? 209.331 166.322 191.054 1.00 41.03  ? 400 LEU A CG  1 
ATOM   4777 C CD1 . LEU B  1 400 ? 210.836 166.207 191.187 1.00 39.83  ? 400 LEU A CD1 1 
ATOM   4778 C CD2 . LEU B  1 400 ? 208.951 166.984 189.745 1.00 44.12  ? 400 LEU A CD2 1 
ATOM   4779 N N   . ASN B  1 401 ? 206.643 162.513 190.835 1.00 47.84  ? 401 ASN A N   1 
ATOM   4780 C CA  . ASN B  1 401 ? 206.253 161.266 190.188 1.00 48.46  ? 401 ASN A CA  1 
ATOM   4781 C C   . ASN B  1 401 ? 204.920 161.416 189.471 1.00 43.76  ? 401 ASN A C   1 
ATOM   4782 O O   . ASN B  1 401 ? 204.715 160.839 188.397 1.00 51.27  ? 401 ASN A O   1 
ATOM   4783 C CB  . ASN B  1 401 ? 206.184 160.138 191.215 1.00 47.50  ? 401 ASN A CB  1 
ATOM   4784 C CG  . ASN B  1 401 ? 206.239 158.770 190.577 1.00 55.34  ? 401 ASN A CG  1 
ATOM   4785 O OD1 . ASN B  1 401 ? 206.271 158.644 189.353 1.00 59.47  ? 401 ASN A OD1 1 
ATOM   4786 N ND2 . ASN B  1 401 ? 206.246 157.733 191.403 1.00 53.22  ? 401 ASN A ND2 1 
ATOM   4787 N N   . SER B  1 402 ? 203.999 162.186 190.048 1.00 40.99  ? 402 SER A N   1 
ATOM   4788 C CA  . SER B  1 402 ? 202.745 162.474 189.362 1.00 43.67  ? 402 SER A CA  1 
ATOM   4789 C C   . SER B  1 402 ? 202.870 163.592 188.336 1.00 54.00  ? 402 SER A C   1 
ATOM   4790 O O   . SER B  1 402 ? 201.971 163.747 187.503 1.00 48.41  ? 402 SER A O   1 
ATOM   4791 C CB  . SER B  1 402 ? 201.661 162.843 190.369 1.00 39.04  ? 402 SER A CB  1 
ATOM   4792 O OG  . SER B  1 402 ? 200.979 161.689 190.824 1.00 44.25  ? 402 SER A OG  1 
ATOM   4793 N N   . LEU B  1 403 ? 203.951 164.370 188.375 1.00 55.79  ? 403 LEU A N   1 
ATOM   4794 C CA  . LEU B  1 403 ? 204.167 165.474 187.448 1.00 48.37  ? 403 LEU A CA  1 
ATOM   4795 C C   . LEU B  1 403 ? 205.264 165.163 186.436 1.00 46.96  ? 403 LEU A C   1 
ATOM   4796 O O   . LEU B  1 403 ? 206.002 166.058 186.021 1.00 58.17  ? 403 LEU A O   1 
ATOM   4797 C CB  . LEU B  1 403 ? 204.502 166.756 188.206 1.00 46.28  ? 403 LEU A CB  1 
ATOM   4798 C CG  . LEU B  1 403 ? 203.388 167.373 189.049 1.00 42.30  ? 403 LEU A CG  1 
ATOM   4799 C CD1 . LEU B  1 403 ? 203.890 168.617 189.759 1.00 45.93  ? 403 LEU A CD1 1 
ATOM   4800 C CD2 . LEU B  1 403 ? 202.186 167.693 188.183 1.00 47.95  ? 403 LEU A CD2 1 
ATOM   4801 N N   . SER B  1 404 ? 205.391 163.896 186.037 1.00 40.70  ? 404 SER A N   1 
ATOM   4802 C CA  . SER B  1 404 ? 206.370 163.542 185.018 1.00 42.47  ? 404 SER A CA  1 
ATOM   4803 C C   . SER B  1 404 ? 206.069 164.210 183.686 1.00 52.61  ? 404 SER A C   1 
ATOM   4804 O O   . SER B  1 404 ? 206.988 164.415 182.883 1.00 63.96  ? 404 SER A O   1 
ATOM   4805 C CB  . SER B  1 404 ? 206.423 162.025 184.843 1.00 44.24  ? 404 SER A CB  1 
ATOM   4806 O OG  . SER B  1 404 ? 205.170 161.516 184.427 1.00 58.07  ? 404 SER A OG  1 
ATOM   4807 N N   . VAL B  1 405 ? 204.806 164.567 183.444 1.00 52.75  ? 405 VAL A N   1 
ATOM   4808 C CA  . VAL B  1 405 ? 204.435 165.195 182.181 1.00 54.62  ? 405 VAL A CA  1 
ATOM   4809 C C   . VAL B  1 405 ? 205.146 166.530 182.028 1.00 53.37  ? 405 VAL A C   1 
ATOM   4810 O O   . VAL B  1 405 ? 205.531 166.921 180.921 1.00 64.32  ? 405 VAL A O   1 
ATOM   4811 C CB  . VAL B  1 405 ? 202.908 165.365 182.095 1.00 58.69  ? 405 VAL A CB  1 
ATOM   4812 C CG1 . VAL B  1 405 ? 202.480 165.571 180.650 1.00 53.35  ? 405 VAL A CG1 1 
ATOM   4813 C CG2 . VAL B  1 405 ? 202.194 164.188 182.735 1.00 62.11  ? 405 VAL A CG2 1 
ATOM   4814 N N   . ILE B  1 406 ? 205.328 167.253 183.134 1.00 44.63  ? 406 ILE A N   1 
ATOM   4815 C CA  . ILE B  1 406 ? 206.010 168.543 183.081 1.00 44.06  ? 406 ILE A CA  1 
ATOM   4816 C C   . ILE B  1 406 ? 207.461 168.361 182.653 1.00 48.23  ? 406 ILE A C   1 
ATOM   4817 O O   . ILE B  1 406 ? 207.976 169.104 181.809 1.00 55.04  ? 406 ILE A O   1 
ATOM   4818 C CB  . ILE B  1 406 ? 205.905 169.256 184.440 1.00 49.13  ? 406 ILE A CB  1 
ATOM   4819 C CG1 . ILE B  1 406 ? 204.535 169.915 184.587 1.00 51.30  ? 406 ILE A CG1 1 
ATOM   4820 C CG2 . ILE B  1 406 ? 207.007 170.286 184.593 1.00 48.90  ? 406 ILE A CG2 1 
ATOM   4821 C CD1 . ILE B  1 406 ? 204.062 170.013 186.014 1.00 58.21  ? 406 ILE A CD1 1 
ATOM   4822 N N   . LEU B  1 407 ? 208.143 167.368 183.229 1.00 50.19  ? 407 LEU A N   1 
ATOM   4823 C CA  . LEU B  1 407 ? 209.531 167.111 182.856 1.00 47.99  ? 407 LEU A CA  1 
ATOM   4824 C C   . LEU B  1 407 ? 209.639 166.675 181.400 1.00 51.26  ? 407 LEU A C   1 
ATOM   4825 O O   . LEU B  1 407 ? 210.544 167.112 180.675 1.00 65.59  ? 407 LEU A O   1 
ATOM   4826 C CB  . LEU B  1 407 ? 210.137 166.053 183.778 1.00 48.48  ? 407 LEU A CB  1 
ATOM   4827 C CG  . LEU B  1 407 ? 210.490 166.496 185.199 1.00 52.40  ? 407 LEU A CG  1 
ATOM   4828 C CD1 . LEU B  1 407 ? 209.307 166.323 186.133 1.00 51.72  ? 407 LEU A CD1 1 
ATOM   4829 C CD2 . LEU B  1 407 ? 211.693 165.727 185.714 1.00 53.24  ? 407 LEU A CD2 1 
ATOM   4830 N N   . MET B  1 408 ? 208.722 165.816 180.952 1.00 55.31  ? 408 MET A N   1 
ATOM   4831 C CA  . MET B  1 408 ? 208.744 165.389 179.558 1.00 59.20  ? 408 MET A CA  1 
ATOM   4832 C C   . MET B  1 408 ? 208.485 166.559 178.618 1.00 72.11  ? 408 MET A C   1 
ATOM   4833 O O   . MET B  1 408 ? 209.100 166.655 177.550 1.00 73.30  ? 408 MET A O   1 
ATOM   4834 C CB  . MET B  1 408 ? 207.721 164.280 179.333 1.00 57.04  ? 408 MET A CB  1 
ATOM   4835 C CG  . MET B  1 408 ? 207.901 163.085 180.246 1.00 64.43  ? 408 MET A CG  1 
ATOM   4836 S SD  . MET B  1 408 ? 206.854 161.720 179.740 1.00 75.12  ? 408 MET A SD  1 
ATOM   4837 C CE  . MET B  1 408 ? 206.904 161.957 177.972 1.00 71.48  ? 408 MET A CE  1 
ATOM   4838 N N   . ASP B  1 409 ? 207.579 167.462 178.997 1.00 64.86  ? 409 ASP A N   1 
ATOM   4839 C CA  . ASP B  1 409 ? 207.299 168.626 178.167 1.00 45.86  ? 409 ASP A CA  1 
ATOM   4840 C C   . ASP B  1 409 ? 208.484 169.579 178.136 1.00 48.95  ? 409 ASP A C   1 
ATOM   4841 O O   . ASP B  1 409 ? 208.759 170.198 177.105 1.00 59.28  ? 409 ASP A O   1 
ATOM   4842 C CB  . ASP B  1 409 ? 206.050 169.340 178.674 1.00 49.89  ? 409 ASP A CB  1 
ATOM   4843 C CG  . ASP B  1 409 ? 204.777 168.628 178.277 1.00 57.55  ? 409 ASP A CG  1 
ATOM   4844 O OD1 . ASP B  1 409 ? 203.703 169.255 178.346 1.00 57.97  ? 409 ASP A OD1 1 
ATOM   4845 O OD2 . ASP B  1 409 ? 204.851 167.442 177.896 1.00 56.78  ? 409 ASP A OD2 1 
ATOM   4846 N N   . LEU B  1 410 ? 209.194 169.716 179.256 1.00 56.76  ? 410 LEU A N   1 
ATOM   4847 C CA  . LEU B  1 410 ? 210.406 170.530 179.269 1.00 54.99  ? 410 LEU A CA  1 
ATOM   4848 C C   . LEU B  1 410 ? 211.462 169.945 178.341 1.00 59.03  ? 410 LEU A C   1 
ATOM   4849 O O   . LEU B  1 410 ? 212.119 170.677 177.587 1.00 64.32  ? 410 LEU A O   1 
ATOM   4850 C CB  . LEU B  1 410 ? 210.941 170.640 180.696 1.00 58.43  ? 410 LEU A CB  1 
ATOM   4851 C CG  . LEU B  1 410 ? 211.655 171.919 181.133 1.00 63.11  ? 410 LEU A CG  1 
ATOM   4852 C CD1 . LEU B  1 410 ? 211.820 171.922 182.643 1.00 60.63  ? 410 LEU A CD1 1 
ATOM   4853 C CD2 . LEU B  1 410 ? 213.004 172.070 180.454 1.00 68.16  ? 410 LEU A CD2 1 
ATOM   4854 N N   . GLU B  1 411 ? 211.637 168.622 178.381 1.00 65.58  ? 411 GLU A N   1 
ATOM   4855 C CA  . GLU B  1 411 ? 212.587 167.980 177.479 1.00 65.18  ? 411 GLU A CA  1 
ATOM   4856 C C   . GLU B  1 411 ? 212.168 168.174 176.027 1.00 70.57  ? 411 GLU A C   1 
ATOM   4857 O O   . GLU B  1 411 ? 213.010 168.430 175.156 1.00 75.93  ? 411 GLU A O   1 
ATOM   4858 C CB  . GLU B  1 411 ? 212.716 166.495 177.838 1.00 65.10  ? 411 GLU A CB  1 
ATOM   4859 C CG  . GLU B  1 411 ? 213.704 165.653 177.012 1.00 75.66  ? 411 GLU A CG  1 
ATOM   4860 C CD  . GLU B  1 411 ? 213.340 165.504 175.550 1.00 76.47  ? 411 GLU A CD  1 
ATOM   4861 O OE1 . GLU B  1 411 ? 214.212 165.752 174.692 1.00 74.69  ? 411 GLU A OE1 1 
ATOM   4862 O OE2 . GLU B  1 411 ? 212.182 165.141 175.260 1.00 76.02  ? 411 GLU A OE2 1 
ATOM   4863 N N   . TYR B  1 412 ? 210.869 168.046 175.745 1.00 64.89  ? 412 TYR A N   1 
ATOM   4864 C CA  . TYR B  1 412 ? 210.388 168.261 174.385 1.00 67.48  ? 412 TYR A CA  1 
ATOM   4865 C C   . TYR B  1 412 ? 210.630 169.695 173.939 1.00 70.16  ? 412 TYR A C   1 
ATOM   4866 O O   . TYR B  1 412 ? 210.997 169.937 172.788 1.00 71.13  ? 412 TYR A O   1 
ATOM   4867 C CB  . TYR B  1 412 ? 208.904 167.919 174.279 1.00 65.30  ? 412 TYR A CB  1 
ATOM   4868 C CG  . TYR B  1 412 ? 208.359 168.132 172.888 1.00 67.12  ? 412 TYR A CG  1 
ATOM   4869 C CD1 . TYR B  1 412 ? 208.769 167.328 171.835 1.00 70.23  ? 412 TYR A CD1 1 
ATOM   4870 C CD2 . TYR B  1 412 ? 207.454 169.146 172.622 1.00 62.05  ? 412 TYR A CD2 1 
ATOM   4871 C CE1 . TYR B  1 412 ? 208.283 167.520 170.560 1.00 67.73  ? 412 TYR A CE1 1 
ATOM   4872 C CE2 . TYR B  1 412 ? 206.962 169.346 171.348 1.00 65.82  ? 412 TYR A CE2 1 
ATOM   4873 C CZ  . TYR B  1 412 ? 207.380 168.529 170.321 1.00 68.84  ? 412 TYR A CZ  1 
ATOM   4874 O OH  . TYR B  1 412 ? 206.894 168.722 169.049 1.00 69.81  ? 412 TYR A OH  1 
ATOM   4875 N N   . MET B  1 413 ? 210.419 170.658 174.836 1.00 70.01  ? 413 MET A N   1 
ATOM   4876 C CA  . MET B  1 413 ? 210.704 172.053 174.521 1.00 65.36  ? 413 MET A CA  1 
ATOM   4877 C C   . MET B  1 413 ? 212.169 172.238 174.158 1.00 71.40  ? 413 MET A C   1 
ATOM   4878 O O   . MET B  1 413 ? 212.498 172.877 173.150 1.00 74.91  ? 413 MET A O   1 
ATOM   4879 C CB  . MET B  1 413 ? 210.338 172.934 175.714 1.00 64.54  ? 413 MET A CB  1 
ATOM   4880 C CG  . MET B  1 413 ? 210.193 174.410 175.403 1.00 64.59  ? 413 MET A CG  1 
ATOM   4881 S SD  . MET B  1 413 ? 210.208 175.387 176.914 1.00 66.58  ? 413 MET A SD  1 
ATOM   4882 C CE  . MET B  1 413 ? 209.381 174.258 178.031 1.00 67.04  ? 413 MET A CE  1 
ATOM   4883 N N   . ILE B  1 414 ? 213.066 171.676 174.970 1.00 67.86  ? 414 ILE A N   1 
ATOM   4884 C CA  . ILE B  1 414 ? 214.495 171.846 174.724 1.00 59.86  ? 414 ILE A CA  1 
ATOM   4885 C C   . ILE B  1 414 ? 214.879 171.234 173.383 1.00 61.52  ? 414 ILE A C   1 
ATOM   4886 O O   . ILE B  1 414 ? 215.559 171.865 172.563 1.00 65.28  ? 414 ILE A O   1 
ATOM   4887 C CB  . ILE B  1 414 ? 215.315 171.241 175.877 1.00 60.85  ? 414 ILE A CB  1 
ATOM   4888 C CG1 . ILE B  1 414 ? 215.105 172.048 177.157 1.00 58.63  ? 414 ILE A CG1 1 
ATOM   4889 C CG2 . ILE B  1 414 ? 216.789 171.201 175.515 1.00 70.82  ? 414 ILE A CG2 1 
ATOM   4890 C CD1 . ILE B  1 414 ? 215.934 171.565 178.322 1.00 58.67  ? 414 ILE A CD1 1 
ATOM   4891 N N   . CYS B  1 415 ? 214.427 170.003 173.129 1.00 78.06  ? 415 CYS A N   1 
ATOM   4892 C CA  . CYS B  1 415 ? 214.772 169.341 171.875 1.00 85.73  ? 415 CYS A CA  1 
ATOM   4893 C C   . CYS B  1 415 ? 214.186 170.080 170.679 1.00 87.67  ? 415 CYS A C   1 
ATOM   4894 O O   . CYS B  1 415 ? 214.856 170.241 169.650 1.00 90.91  ? 415 CYS A O   1 
ATOM   4895 C CB  . CYS B  1 415 ? 214.294 167.889 171.893 1.00 83.31  ? 415 CYS A CB  1 
ATOM   4896 S SG  . CYS B  1 415 ? 212.593 167.647 171.325 1.00 87.82  ? 415 CYS A SG  1 
ATOM   4897 N N   . PHE B  1 416 ? 212.927 170.513 170.785 1.00 82.89  ? 416 PHE A N   1 
ATOM   4898 C CA  . PHE B  1 416 ? 212.270 171.204 169.685 1.00 80.99  ? 416 PHE A CA  1 
ATOM   4899 C C   . PHE B  1 416 ? 212.984 172.502 169.350 1.00 83.93  ? 416 PHE A C   1 
ATOM   4900 O O   . PHE B  1 416 ? 213.231 172.798 168.176 1.00 85.46  ? 416 PHE A O   1 
ATOM   4901 C CB  . PHE B  1 416 ? 210.809 171.469 170.050 1.00 85.11  ? 416 PHE A CB  1 
ATOM   4902 C CG  . PHE B  1 416 ? 210.017 172.131 168.964 1.00 85.34  ? 416 PHE A CG  1 
ATOM   4903 C CD1 . PHE B  1 416 ? 210.036 171.637 167.674 1.00 87.84  ? 416 PHE A CD1 1 
ATOM   4904 C CD2 . PHE B  1 416 ? 209.242 173.244 169.238 1.00 81.31  ? 416 PHE A CD2 1 
ATOM   4905 C CE1 . PHE B  1 416 ? 209.303 172.243 166.675 1.00 85.74  ? 416 PHE A CE1 1 
ATOM   4906 C CE2 . PHE B  1 416 ? 208.508 173.853 168.244 1.00 83.08  ? 416 PHE A CE2 1 
ATOM   4907 C CZ  . PHE B  1 416 ? 208.538 173.352 166.961 1.00 82.89  ? 416 PHE A CZ  1 
ATOM   4908 N N   . TYR B  1 417 ? 213.355 173.276 170.373 1.00 85.73  ? 417 TYR A N   1 
ATOM   4909 C CA  . TYR B  1 417 ? 214.044 174.533 170.120 1.00 83.99  ? 417 TYR A CA  1 
ATOM   4910 C C   . TYR B  1 417 ? 215.458 174.306 169.610 1.00 84.36  ? 417 TYR A C   1 
ATOM   4911 O O   . TYR B  1 417 ? 215.976 175.125 168.842 1.00 89.34  ? 417 TYR A O   1 
ATOM   4912 C CB  . TYR B  1 417 ? 214.059 175.386 171.386 1.00 79.51  ? 417 TYR A CB  1 
ATOM   4913 C CG  . TYR B  1 417 ? 212.804 176.206 171.562 1.00 80.48  ? 417 TYR A CG  1 
ATOM   4914 C CD1 . TYR B  1 417 ? 211.644 175.883 170.875 1.00 81.94  ? 417 TYR A CD1 1 
ATOM   4915 C CD2 . TYR B  1 417 ? 212.782 177.307 172.403 1.00 83.05  ? 417 TYR A CD2 1 
ATOM   4916 C CE1 . TYR B  1 417 ? 210.496 176.626 171.027 1.00 80.37  ? 417 TYR A CE1 1 
ATOM   4917 C CE2 . TYR B  1 417 ? 211.636 178.058 172.559 1.00 83.51  ? 417 TYR A CE2 1 
ATOM   4918 C CZ  . TYR B  1 417 ? 210.498 177.713 171.869 1.00 81.63  ? 417 TYR A CZ  1 
ATOM   4919 O OH  . TYR B  1 417 ? 209.356 178.459 172.022 1.00 87.46  ? 417 TYR A OH  1 
ATOM   4920 N N   . SER B  1 418 ? 216.100 173.210 170.016 1.00 82.80  ? 418 SER A N   1 
ATOM   4921 C CA  . SER B  1 418 ? 217.459 172.958 169.557 1.00 86.02  ? 418 SER A CA  1 
ATOM   4922 C C   . SER B  1 418 ? 217.500 172.450 168.119 1.00 87.54  ? 418 SER A C   1 
ATOM   4923 O O   . SER B  1 418 ? 218.419 172.798 167.369 1.00 92.06  ? 418 SER A O   1 
ATOM   4924 C CB  . SER B  1 418 ? 218.152 171.977 170.502 1.00 86.48  ? 418 SER A CB  1 
ATOM   4925 O OG  . SER B  1 418 ? 217.312 170.880 170.800 1.00 86.60  ? 418 SER A OG  1 
ATOM   4926 N N   . LEU B  1 419 ? 216.528 171.634 167.704 1.00 86.41  ? 419 LEU A N   1 
ATOM   4927 C CA  . LEU B  1 419 ? 216.564 171.035 166.372 1.00 88.61  ? 419 LEU A CA  1 
ATOM   4928 C C   . LEU B  1 419 ? 215.456 171.533 165.452 1.00 89.87  ? 419 LEU A C   1 
ATOM   4929 O O   . LEU B  1 419 ? 215.743 172.059 164.373 1.00 88.43  ? 419 LEU A O   1 
ATOM   4930 C CB  . LEU B  1 419 ? 216.504 169.499 166.460 1.00 87.95  ? 419 LEU A CB  1 
ATOM   4931 C CG  . LEU B  1 419 ? 217.660 168.660 167.022 1.00 88.18  ? 419 LEU A CG  1 
ATOM   4932 C CD1 . LEU B  1 419 ? 217.889 168.871 168.507 1.00 85.09  ? 419 LEU A CD1 1 
ATOM   4933 C CD2 . LEU B  1 419 ? 217.427 167.185 166.725 1.00 88.63  ? 419 LEU A CD2 1 
ATOM   4934 N N   . GLU B  1 420 ? 214.192 171.381 165.842 1.00 99.38  ? 420 GLU A N   1 
ATOM   4935 C CA  . GLU B  1 420 ? 213.076 171.489 164.911 1.00 100.20 ? 420 GLU A CA  1 
ATOM   4936 C C   . GLU B  1 420 ? 212.359 172.834 164.974 1.00 99.01  ? 420 GLU A C   1 
ATOM   4937 O O   . GLU B  1 420 ? 211.351 173.015 164.284 1.00 98.70  ? 420 GLU A O   1 
ATOM   4938 C CB  . GLU B  1 420 ? 212.081 170.348 165.172 1.00 98.58  ? 420 GLU A CB  1 
ATOM   4939 C CG  . GLU B  1 420 ? 211.122 170.032 164.027 1.00 97.86  ? 420 GLU A CG  1 
ATOM   4940 C CD  . GLU B  1 420 ? 211.835 169.724 162.725 1.00 100.57 ? 420 GLU A CD  1 
ATOM   4941 O OE1 . GLU B  1 420 ? 212.926 169.118 162.768 1.00 103.34 ? 420 GLU A OE1 1 
ATOM   4942 O OE2 . GLU B  1 420 ? 211.302 170.089 161.656 1.00 98.67  ? 420 GLU A OE2 1 
ATOM   4943 N N   . LEU B  1 421 ? 212.855 173.787 165.766 1.00 96.62  ? 421 LEU A N   1 
ATOM   4944 C CA  . LEU B  1 421 ? 212.124 175.039 165.947 1.00 95.35  ? 421 LEU A CA  1 
ATOM   4945 C C   . LEU B  1 421 ? 212.042 175.850 164.659 1.00 94.47  ? 421 LEU A C   1 
ATOM   4946 O O   . LEU B  1 421 ? 211.041 176.541 164.433 1.00 95.06  ? 421 LEU A O   1 
ATOM   4947 C CB  . LEU B  1 421 ? 212.765 175.872 167.055 1.00 93.65  ? 421 LEU A CB  1 
ATOM   4948 C CG  . LEU B  1 421 ? 212.182 177.274 167.252 1.00 95.11  ? 421 LEU A CG  1 
ATOM   4949 C CD1 . LEU B  1 421 ? 210.694 177.194 167.551 1.00 94.83  ? 421 LEU A CD1 1 
ATOM   4950 C CD2 . LEU B  1 421 ? 212.906 178.011 168.358 1.00 95.01  ? 421 LEU A CD2 1 
ATOM   4951 N N   . LYS B  1 422 ? 213.063 175.773 163.803 1.00 97.39  ? 422 LYS A N   1 
ATOM   4952 C CA  . LYS B  1 422 ? 213.149 176.594 162.594 1.00 97.92  ? 422 LYS A CA  1 
ATOM   4953 C C   . LYS B  1 422 ? 213.129 178.083 162.956 1.00 99.99  ? 422 LYS A C   1 
ATOM   4954 O O   . LYS B  1 422 ? 212.181 178.819 162.675 1.00 100.03 ? 422 LYS A O   1 
ATOM   4955 C CB  . LYS B  1 422 ? 212.034 176.240 161.601 1.00 94.05  ? 422 LYS A CB  1 
ATOM   4956 C CG  . LYS B  1 422 ? 211.919 174.755 161.302 1.00 96.53  ? 422 LYS A CG  1 
ATOM   4957 C CD  . LYS B  1 422 ? 213.263 174.182 160.882 1.00 97.09  ? 422 LYS A CD  1 
ATOM   4958 C CE  . LYS B  1 422 ? 213.222 172.666 160.800 1.00 98.88  ? 422 LYS A CE  1 
ATOM   4959 N NZ  . LYS B  1 422 ? 214.590 172.083 160.702 1.00 98.14  ? 422 LYS A NZ  1 
ATOM   4960 N N   . TRP B  1 423 ? 214.219 178.491 163.616 1.00 96.98  ? 423 TRP A N   1 
ATOM   4961 C CA  . TRP B  1 423 ? 214.358 179.860 164.109 1.00 91.86  ? 423 TRP A CA  1 
ATOM   4962 C C   . TRP B  1 423 ? 214.081 180.887 163.018 1.00 93.46  ? 423 TRP A C   1 
ATOM   4963 O O   . TRP B  1 423 ? 213.459 181.925 163.273 1.00 95.34  ? 423 TRP A O   1 
ATOM   4964 C CB  . TRP B  1 423 ? 215.767 180.063 164.665 1.00 91.36  ? 423 TRP A CB  1 
ATOM   4965 C CG  . TRP B  1 423 ? 216.055 179.326 165.938 1.00 94.46  ? 423 TRP A CG  1 
ATOM   4966 C CD1 . TRP B  1 423 ? 216.694 178.128 166.059 1.00 95.65  ? 423 TRP A CD1 1 
ATOM   4967 C CD2 . TRP B  1 423 ? 215.767 179.763 167.272 1.00 93.77  ? 423 TRP A CD2 1 
ATOM   4968 N NE1 . TRP B  1 423 ? 216.796 177.777 167.382 1.00 96.11  ? 423 TRP A NE1 1 
ATOM   4969 C CE2 . TRP B  1 423 ? 216.238 178.766 168.148 1.00 94.92  ? 423 TRP A CE2 1 
ATOM   4970 C CE3 . TRP B  1 423 ? 215.147 180.894 167.809 1.00 91.99  ? 423 TRP A CE3 1 
ATOM   4971 C CZ2 . TRP B  1 423 ? 216.108 178.865 169.532 1.00 91.82  ? 423 TRP A CZ2 1 
ATOM   4972 C CZ3 . TRP B  1 423 ? 215.019 180.990 169.184 1.00 92.84  ? 423 TRP A CZ3 1 
ATOM   4973 C CH2 . TRP B  1 423 ? 215.497 179.982 170.028 1.00 89.61  ? 423 TRP A CH2 1 
ATOM   4974 N N   . ASP B  1 424 ? 214.544 180.619 161.794 1.00 103.97 ? 424 ASP A N   1 
ATOM   4975 C CA  . ASP B  1 424 ? 214.365 181.572 160.704 1.00 104.99 ? 424 ASP A CA  1 
ATOM   4976 C C   . ASP B  1 424 ? 212.891 181.773 160.372 1.00 106.30 ? 424 ASP A C   1 
ATOM   4977 O O   . ASP B  1 424 ? 212.463 182.893 160.070 1.00 103.02 ? 424 ASP A O   1 
ATOM   4978 C CB  . ASP B  1 424 ? 215.132 181.103 159.467 1.00 104.22 ? 424 ASP A CB  1 
ATOM   4979 C CG  . ASP B  1 424 ? 214.923 179.629 159.177 1.00 105.40 ? 424 ASP A CG  1 
ATOM   4980 O OD1 . ASP B  1 424 ? 214.202 178.965 159.949 1.00 107.74 ? 424 ASP A OD1 1 
ATOM   4981 O OD2 . ASP B  1 424 ? 215.481 179.135 158.175 1.00 103.32 ? 424 ASP A OD2 1 
ATOM   4982 N N   . GLU B  1 425 ? 212.104 180.701 160.413 1.00 111.91 ? 425 GLU A N   1 
ATOM   4983 C CA  . GLU B  1 425 ? 210.694 180.790 160.060 1.00 110.69 ? 425 GLU A CA  1 
ATOM   4984 C C   . GLU B  1 425 ? 209.942 181.676 161.046 1.00 110.24 ? 425 GLU A C   1 
ATOM   4985 O O   . GLU B  1 425 ? 210.174 181.624 162.257 1.00 105.87 ? 425 GLU A O   1 
ATOM   4986 C CB  . GLU B  1 425 ? 210.071 179.394 160.024 1.00 110.94 ? 425 GLU A CB  1 
ATOM   4987 C CG  . GLU B  1 425 ? 208.628 179.363 159.545 1.00 110.81 ? 425 GLU A CG  1 
ATOM   4988 C CD  . GLU B  1 425 ? 208.132 177.953 159.282 1.00 110.09 ? 425 GLU A CD  1 
ATOM   4989 O OE1 . GLU B  1 425 ? 208.917 177.000 159.469 1.00 110.35 ? 425 GLU A OE1 1 
ATOM   4990 O OE2 . GLU B  1 425 ? 206.957 177.799 158.889 1.00 108.70 ? 425 GLU A OE2 1 
ATOM   4991 N N   . SER B  1 426 ? 209.035 182.500 160.515 1.00 114.05 ? 426 SER A N   1 
ATOM   4992 C CA  . SER B  1 426 ? 208.247 183.383 161.368 1.00 114.08 ? 426 SER A CA  1 
ATOM   4993 C C   . SER B  1 426 ? 207.207 182.611 162.169 1.00 112.76 ? 426 SER A C   1 
ATOM   4994 O O   . SER B  1 426 ? 206.776 183.074 163.230 1.00 111.35 ? 426 SER A O   1 
ATOM   4995 C CB  . SER B  1 426 ? 207.572 184.464 160.525 1.00 112.75 ? 426 SER A CB  1 
ATOM   4996 O OG  . SER B  1 426 ? 206.622 183.899 159.639 1.00 111.97 ? 426 SER A OG  1 
ATOM   4997 N N   . LYS B  1 427 ? 206.790 181.447 161.679 1.00 114.38 ? 427 LYS A N   1 
ATOM   4998 C CA  . LYS B  1 427 ? 205.853 180.563 162.366 1.00 115.79 ? 427 LYS A CA  1 
ATOM   4999 C C   . LYS B  1 427 ? 206.447 179.165 162.475 1.00 116.38 ? 427 LYS A C   1 
ATOM   5000 O O   . LYS B  1 427 ? 205.811 178.159 162.154 1.00 116.20 ? 427 LYS A O   1 
ATOM   5001 C CB  . LYS B  1 427 ? 204.505 180.528 161.654 1.00 112.55 ? 427 LYS A CB  1 
ATOM   5002 C CG  . LYS B  1 427 ? 203.864 181.892 161.463 1.00 112.40 ? 427 LYS A CG  1 
ATOM   5003 C CD  . LYS B  1 427 ? 202.572 181.783 160.671 1.00 113.54 ? 427 LYS A CD  1 
ATOM   5004 C CE  . LYS B  1 427 ? 201.909 183.139 160.506 1.00 114.07 ? 427 LYS A CE  1 
ATOM   5005 N NZ  . LYS B  1 427 ? 200.621 183.038 159.766 1.00 114.10 ? 427 LYS A NZ  1 
ATOM   5006 N N   . GLY B  1 428 ? 207.701 179.099 162.926 1.00 110.95 ? 428 GLY A N   1 
ATOM   5007 C CA  . GLY B  1 428 ? 208.406 177.828 162.961 1.00 111.07 ? 428 GLY A CA  1 
ATOM   5008 C C   . GLY B  1 428 ? 207.766 176.812 163.888 1.00 110.61 ? 428 GLY A C   1 
ATOM   5009 O O   . GLY B  1 428 ? 207.694 175.624 163.566 1.00 110.09 ? 428 GLY A O   1 
ATOM   5010 N N   . LEU B  1 429 ? 207.287 177.262 165.049 1.00 100.17 ? 429 LEU A N   1 
ATOM   5011 C CA  . LEU B  1 429 ? 206.737 176.329 166.026 1.00 102.76 ? 429 LEU A CA  1 
ATOM   5012 C C   . LEU B  1 429 ? 205.407 175.725 165.591 1.00 105.41 ? 429 LEU A C   1 
ATOM   5013 O O   . LEU B  1 429 ? 204.855 174.896 166.323 1.00 108.93 ? 429 LEU A O   1 
ATOM   5014 C CB  . LEU B  1 429 ? 206.582 177.015 167.386 1.00 99.17  ? 429 LEU A CB  1 
ATOM   5015 C CG  . LEU B  1 429 ? 205.273 177.735 167.709 1.00 98.62  ? 429 LEU A CG  1 
ATOM   5016 C CD1 . LEU B  1 429 ? 205.261 178.162 169.169 1.00 94.61  ? 429 LEU A CD1 1 
ATOM   5017 C CD2 . LEU B  1 429 ? 205.069 178.927 166.796 1.00 102.30 ? 429 LEU A CD2 1 
ATOM   5018 N N   . LEU B  1 430 ? 204.888 176.106 164.427 1.00 107.86 ? 430 LEU A N   1 
ATOM   5019 C CA  . LEU B  1 430 ? 203.696 175.494 163.842 1.00 107.64 ? 430 LEU A CA  1 
ATOM   5020 C C   . LEU B  1 430 ? 204.023 175.091 162.408 1.00 107.82 ? 430 LEU A C   1 
ATOM   5021 O O   . LEU B  1 430 ? 203.633 175.770 161.450 1.00 105.18 ? 430 LEU A O   1 
ATOM   5022 C CB  . LEU B  1 430 ? 202.502 176.448 163.897 1.00 108.51 ? 430 LEU A CB  1 
ATOM   5023 C CG  . LEU B  1 430 ? 202.113 177.010 165.267 1.00 106.17 ? 430 LEU A CG  1 
ATOM   5024 C CD1 . LEU B  1 430 ? 200.967 178.001 165.137 1.00 105.90 ? 430 LEU A CD1 1 
ATOM   5025 C CD2 . LEU B  1 430 ? 201.748 175.893 166.229 1.00 103.47 ? 430 LEU A CD2 1 
ATOM   5026 N N   . PRO B  1 431 ? 204.758 173.995 162.229 1.00 123.28 ? 431 PRO A N   1 
ATOM   5027 C CA  . PRO B  1 431 ? 205.198 173.611 160.883 1.00 123.34 ? 431 PRO A CA  1 
ATOM   5028 C C   . PRO B  1 431 ? 204.054 173.099 160.020 1.00 121.88 ? 431 PRO A C   1 
ATOM   5029 O O   . PRO B  1 431 ? 203.069 172.542 160.511 1.00 122.30 ? 431 PRO A O   1 
ATOM   5030 C CB  . PRO B  1 431 ? 206.227 172.507 161.149 1.00 121.68 ? 431 PRO A CB  1 
ATOM   5031 C CG  . PRO B  1 431 ? 205.815 171.923 162.455 1.00 121.32 ? 431 PRO A CG  1 
ATOM   5032 C CD  . PRO B  1 431 ? 205.201 173.037 163.257 1.00 118.69 ? 431 PRO A CD  1 
ATOM   5033 N N   . ASN B  1 432 ? 204.209 173.285 158.707 1.00 130.06 ? 432 ASN A N   1 
ATOM   5034 C CA  . ASN B  1 432 ? 203.184 172.870 157.755 1.00 132.32 ? 432 ASN A CA  1 
ATOM   5035 C C   . ASN B  1 432 ? 203.091 171.357 157.619 1.00 131.69 ? 432 ASN A C   1 
ATOM   5036 O O   . ASN B  1 432 ? 201.989 170.823 157.443 1.00 131.14 ? 432 ASN A O   1 
ATOM   5037 C CB  . ASN B  1 432 ? 203.461 173.478 156.379 1.00 131.57 ? 432 ASN A CB  1 
ATOM   5038 C CG  . ASN B  1 432 ? 204.148 174.820 156.464 1.00 131.04 ? 432 ASN A CG  1 
ATOM   5039 O OD1 . ASN B  1 432 ? 203.521 175.836 156.763 1.00 130.53 ? 432 ASN A OD1 1 
ATOM   5040 N ND2 . ASN B  1 432 ? 205.446 174.833 156.207 1.00 130.71 ? 432 ASN A ND2 1 
ATOM   5041 N N   . ASN B  1 433 ? 204.223 170.659 157.688 1.00 141.18 ? 433 ASN A N   1 
ATOM   5042 C CA  . ASN B  1 433 ? 204.281 169.234 157.371 1.00 142.14 ? 433 ASN A CA  1 
ATOM   5043 C C   . ASN B  1 433 ? 203.402 168.446 158.332 1.00 142.16 ? 433 ASN A C   1 
ATOM   5044 O O   . ASN B  1 433 ? 203.673 168.394 159.537 1.00 141.53 ? 433 ASN A O   1 
ATOM   5045 C CB  . ASN B  1 433 ? 205.725 168.746 157.427 1.00 141.44 ? 433 ASN A CB  1 
ATOM   5046 C CG  . ASN B  1 433 ? 206.516 169.125 156.190 1.00 141.36 ? 433 ASN A CG  1 
ATOM   5047 O OD1 . ASN B  1 433 ? 206.166 170.069 155.481 1.00 141.58 ? 433 ASN A OD1 1 
ATOM   5048 N ND2 . ASN B  1 433 ? 207.593 168.392 155.928 1.00 140.58 ? 433 ASN A ND2 1 
ATOM   5049 N N   . SER B  1 434 ? 202.342 167.833 157.798 1.00 145.92 ? 434 SER A N   1 
ATOM   5050 C CA  . SER B  1 434 ? 201.485 166.983 158.617 1.00 145.87 ? 434 SER A CA  1 
ATOM   5051 C C   . SER B  1 434 ? 202.253 165.780 159.146 1.00 146.51 ? 434 SER A C   1 
ATOM   5052 O O   . SER B  1 434 ? 202.077 165.380 160.303 1.00 145.42 ? 434 SER A O   1 
ATOM   5053 C CB  . SER B  1 434 ? 200.268 166.534 157.810 1.00 144.11 ? 434 SER A CB  1 
ATOM   5054 O OG  . SER B  1 434 ? 200.654 166.031 156.543 1.00 143.39 ? 434 SER A OG  1 
ATOM   5055 N N   . GLU B  1 435 ? 203.106 165.187 158.313 1.00 152.36 ? 435 GLU A N   1 
ATOM   5056 C CA  . GLU B  1 435 ? 203.932 164.069 158.746 1.00 152.44 ? 435 GLU A CA  1 
ATOM   5057 C C   . GLU B  1 435 ? 204.965 164.558 159.754 1.00 151.82 ? 435 GLU A C   1 
ATOM   5058 O O   . GLU B  1 435 ? 205.782 165.431 159.443 1.00 150.96 ? 435 GLU A O   1 
ATOM   5059 C CB  . GLU B  1 435 ? 204.615 163.419 157.546 1.00 150.62 ? 435 GLU A CB  1 
ATOM   5060 C CG  . GLU B  1 435 ? 203.676 162.634 156.643 1.00 149.77 ? 435 GLU A CG  1 
ATOM   5061 C CD  . GLU B  1 435 ? 204.417 161.769 155.641 1.00 150.14 ? 435 GLU A CD  1 
ATOM   5062 O OE1 . GLU B  1 435 ? 205.580 162.092 155.320 1.00 151.96 ? 435 GLU A OE1 1 
ATOM   5063 O OE2 . GLU B  1 435 ? 203.836 160.767 155.173 1.00 150.08 ? 435 GLU A OE2 1 
ATOM   5064 N N   . GLU B  1 436 ? 204.927 163.996 160.962 1.00 141.84 ? 436 GLU A N   1 
ATOM   5065 C CA  . GLU B  1 436 ? 205.827 164.407 162.040 1.00 140.01 ? 436 GLU A CA  1 
ATOM   5066 C C   . GLU B  1 436 ? 207.148 163.646 161.913 1.00 140.02 ? 436 GLU A C   1 
ATOM   5067 O O   . GLU B  1 436 ? 207.468 162.734 162.679 1.00 138.43 ? 436 GLU A O   1 
ATOM   5068 C CB  . GLU B  1 436 ? 205.169 164.179 163.394 1.00 138.87 ? 436 GLU A CB  1 
ATOM   5069 C CG  . GLU B  1 436 ? 204.041 165.149 163.704 1.00 139.14 ? 436 GLU A CG  1 
ATOM   5070 C CD  . GLU B  1 436 ? 203.611 165.100 165.158 1.00 139.68 ? 436 GLU A CD  1 
ATOM   5071 O OE1 . GLU B  1 436 ? 203.181 164.021 165.617 1.00 138.68 ? 436 GLU A OE1 1 
ATOM   5072 O OE2 . GLU B  1 436 ? 203.703 166.141 165.841 1.00 140.32 ? 436 GLU A OE2 1 
ATOM   5073 N N   . SER B  1 437 ? 207.927 164.045 160.906 1.00 144.46 ? 437 SER A N   1 
ATOM   5074 C CA  . SER B  1 437 ? 209.215 163.414 160.651 1.00 143.67 ? 437 SER A CA  1 
ATOM   5075 C C   . SER B  1 437 ? 210.285 163.825 161.653 1.00 143.93 ? 437 SER A C   1 
ATOM   5076 O O   . SER B  1 437 ? 211.310 163.142 161.749 1.00 142.80 ? 437 SER A O   1 
ATOM   5077 C CB  . SER B  1 437 ? 209.688 163.740 159.233 1.00 142.16 ? 437 SER A CB  1 
ATOM   5078 O OG  . SER B  1 437 ? 209.876 165.134 159.066 1.00 140.74 ? 437 SER A OG  1 
ATOM   5079 N N   . GLY B  1 438 ? 210.079 164.916 162.388 1.00 134.36 ? 438 GLY A N   1 
ATOM   5080 C CA  . GLY B  1 438 ? 211.059 165.325 163.374 1.00 130.61 ? 438 GLY A CA  1 
ATOM   5081 C C   . GLY B  1 438 ? 211.221 164.290 164.471 1.00 130.01 ? 438 GLY A C   1 
ATOM   5082 O O   . GLY B  1 438 ? 210.256 163.684 164.936 1.00 128.77 ? 438 GLY A O   1 
ATOM   5083 N N   . ILE B  1 439 ? 212.475 164.090 164.890 1.00 128.03 ? 439 ILE A N   1 
ATOM   5084 C CA  . ILE B  1 439 ? 212.784 163.074 165.894 1.00 130.43 ? 439 ILE A CA  1 
ATOM   5085 C C   . ILE B  1 439 ? 212.440 163.513 167.306 1.00 127.54 ? 439 ILE A C   1 
ATOM   5086 O O   . ILE B  1 439 ? 212.679 162.754 168.254 1.00 128.19 ? 439 ILE A O   1 
ATOM   5087 C CB  . ILE B  1 439 ? 214.275 162.684 165.838 1.00 129.28 ? 439 ILE A CB  1 
ATOM   5088 C CG1 . ILE B  1 439 ? 215.153 163.936 165.813 1.00 128.65 ? 439 ILE A CG1 1 
ATOM   5089 C CG2 . ILE B  1 439 ? 214.551 161.811 164.625 1.00 126.04 ? 439 ILE A CG2 1 
ATOM   5090 C CD1 . ILE B  1 439 ? 216.635 163.640 165.814 1.00 127.96 ? 439 ILE A CD1 1 
ATOM   5091 N N   . CYS B  1 440 ? 211.889 164.716 167.480 1.00 116.35 ? 440 CYS A N   1 
ATOM   5092 C CA  . CYS B  1 440 ? 211.572 165.195 168.821 1.00 117.70 ? 440 CYS A CA  1 
ATOM   5093 C C   . CYS B  1 440 ? 210.393 164.436 169.415 1.00 117.20 ? 440 CYS A C   1 
ATOM   5094 O O   . CYS B  1 440 ? 210.442 163.999 170.570 1.00 115.74 ? 440 CYS A O   1 
ATOM   5095 C CB  . CYS B  1 440 ? 211.291 166.693 168.782 1.00 118.60 ? 440 CYS A CB  1 
ATOM   5096 S SG  . CYS B  1 440 ? 212.704 167.663 169.296 1.00 122.90 ? 440 CYS A SG  1 
ATOM   5097 N N   . HIS B  1 441 ? 209.318 164.275 168.641 1.00 126.10 ? 441 HIS A N   1 
ATOM   5098 C CA  . HIS B  1 441 ? 208.231 163.411 169.077 1.00 125.63 ? 441 HIS A CA  1 
ATOM   5099 C C   . HIS B  1 441 ? 208.627 161.943 169.024 1.00 126.03 ? 441 HIS A C   1 
ATOM   5100 O O   . HIS B  1 441 ? 207.948 161.106 169.627 1.00 124.95 ? 441 HIS A O   1 
ATOM   5101 C CB  . HIS B  1 441 ? 206.984 163.651 168.224 1.00 125.19 ? 441 HIS A CB  1 
ATOM   5102 C CG  . HIS B  1 441 ? 206.939 162.827 166.976 1.00 127.99 ? 441 HIS A CG  1 
ATOM   5103 N ND1 . HIS B  1 441 ? 206.341 161.586 166.924 1.00 129.83 ? 441 HIS A ND1 1 
ATOM   5104 C CD2 . HIS B  1 441 ? 207.423 163.063 165.735 1.00 126.35 ? 441 HIS A CD2 1 
ATOM   5105 C CE1 . HIS B  1 441 ? 206.457 161.095 165.703 1.00 127.00 ? 441 HIS A CE1 1 
ATOM   5106 N NE2 . HIS B  1 441 ? 207.109 161.972 164.962 1.00 126.59 ? 441 HIS A NE2 1 
ATOM   5107 N N   . LYS B  1 442 ? 209.705 161.617 168.313 1.00 127.09 ? 442 LYS A N   1 
ATOM   5108 C CA  . LYS B  1 442 ? 210.225 160.263 168.257 1.00 126.83 ? 442 LYS A CA  1 
ATOM   5109 C C   . LYS B  1 442 ? 211.218 160.039 169.396 1.00 127.28 ? 442 LYS A C   1 
ATOM   5110 O O   . LYS B  1 442 ? 211.497 160.930 170.201 1.00 125.93 ? 442 LYS A O   1 
ATOM   5111 C CB  . LYS B  1 442 ? 210.863 159.993 166.895 1.00 125.43 ? 442 LYS A CB  1 
ATOM   5112 C CG  . LYS B  1 442 ? 209.889 160.097 165.735 1.00 123.04 ? 442 LYS A CG  1 
ATOM   5113 C CD  . LYS B  1 442 ? 210.602 159.985 164.399 1.00 124.99 ? 442 LYS A CD  1 
ATOM   5114 C CE  . LYS B  1 442 ? 209.632 160.164 163.244 1.00 126.87 ? 442 LYS A CE  1 
ATOM   5115 N NZ  . LYS B  1 442 ? 210.332 160.203 161.932 1.00 127.24 ? 442 LYS A NZ  1 
ATOM   5116 N N   . TYR B  1 443 ? 211.758 158.824 169.467 1.00 120.84 ? 443 TYR A N   1 
ATOM   5117 C CA  . TYR B  1 443 ? 212.554 158.383 170.607 1.00 120.33 ? 443 TYR A CA  1 
ATOM   5118 C C   . TYR B  1 443 ? 213.786 157.624 170.137 1.00 119.77 ? 443 TYR A C   1 
ATOM   5119 O O   . TYR B  1 443 ? 214.161 156.597 170.712 1.00 119.91 ? 443 TYR A O   1 
ATOM   5120 C CB  . TYR B  1 443 ? 211.711 157.523 171.546 1.00 119.88 ? 443 TYR A CB  1 
ATOM   5121 C CG  . TYR B  1 443 ? 210.248 157.895 171.513 1.00 119.43 ? 443 TYR A CG  1 
ATOM   5122 C CD1 . TYR B  1 443 ? 209.782 159.019 172.182 1.00 117.64 ? 443 TYR A CD1 1 
ATOM   5123 C CD2 . TYR B  1 443 ? 209.342 157.158 170.761 1.00 120.61 ? 443 TYR A CD2 1 
ATOM   5124 C CE1 . TYR B  1 443 ? 208.448 159.373 172.138 1.00 121.02 ? 443 TYR A CE1 1 
ATOM   5125 C CE2 . TYR B  1 443 ? 208.008 157.508 170.709 1.00 120.66 ? 443 TYR A CE2 1 
ATOM   5126 C CZ  . TYR B  1 443 ? 207.565 158.615 171.400 1.00 122.48 ? 443 TYR A CZ  1 
ATOM   5127 O OH  . TYR B  1 443 ? 206.235 158.966 171.350 1.00 121.45 ? 443 TYR A OH  1 
ATOM   5128 N N   . THR B  1 444 ? 214.430 158.118 169.077 1.00 125.22 ? 444 THR A N   1 
ATOM   5129 C CA  . THR B  1 444 ? 215.604 157.436 168.540 1.00 129.07 ? 444 THR A CA  1 
ATOM   5130 C C   . THR B  1 444 ? 216.759 157.445 169.536 1.00 127.47 ? 444 THR A C   1 
ATOM   5131 O O   . THR B  1 444 ? 217.407 156.414 169.752 1.00 125.71 ? 444 THR A O   1 
ATOM   5132 C CB  . THR B  1 444 ? 216.027 158.083 167.221 1.00 127.04 ? 444 THR A CB  1 
ATOM   5133 O OG1 . THR B  1 444 ? 215.004 157.880 166.238 1.00 124.95 ? 444 THR A OG1 1 
ATOM   5134 C CG2 . THR B  1 444 ? 217.328 157.473 166.719 1.00 124.95 ? 444 THR A CG2 1 
ATOM   5135 N N   . TYR B  1 445 ? 217.029 158.596 170.156 1.00 118.13 ? 445 TYR A N   1 
ATOM   5136 C CA  . TYR B  1 445 ? 218.113 158.671 171.130 1.00 116.53 ? 445 TYR A CA  1 
ATOM   5137 C C   . TYR B  1 445 ? 217.781 157.907 172.405 1.00 118.36 ? 445 TYR A C   1 
ATOM   5138 O O   . TYR B  1 445 ? 218.678 157.329 173.029 1.00 118.43 ? 445 TYR A O   1 
ATOM   5139 C CB  . TYR B  1 445 ? 218.430 160.129 171.460 1.00 117.11 ? 445 TYR A CB  1 
ATOM   5140 C CG  . TYR B  1 445 ? 218.773 160.980 170.259 1.00 119.38 ? 445 TYR A CG  1 
ATOM   5141 C CD1 . TYR B  1 445 ? 219.802 160.621 169.399 1.00 119.93 ? 445 TYR A CD1 1 
ATOM   5142 C CD2 . TYR B  1 445 ? 218.072 162.148 169.990 1.00 118.10 ? 445 TYR A CD2 1 
ATOM   5143 C CE1 . TYR B  1 445 ? 220.120 161.399 168.302 1.00 120.90 ? 445 TYR A CE1 1 
ATOM   5144 C CE2 . TYR B  1 445 ? 218.383 162.933 168.897 1.00 116.98 ? 445 TYR A CE2 1 
ATOM   5145 C CZ  . TYR B  1 445 ? 219.407 162.554 168.056 1.00 119.61 ? 445 TYR A CZ  1 
ATOM   5146 O OH  . TYR B  1 445 ? 219.719 163.333 166.965 1.00 116.02 ? 445 TYR A OH  1 
ATOM   5147 N N   . GLY B  1 446 ? 216.512 157.889 172.804 1.00 99.65  ? 446 GLY A N   1 
ATOM   5148 C CA  . GLY B  1 446 ? 216.120 157.247 174.040 1.00 95.84  ? 446 GLY A CA  1 
ATOM   5149 C C   . GLY B  1 446 ? 216.255 158.103 175.276 1.00 92.79  ? 446 GLY A C   1 
ATOM   5150 O O   . GLY B  1 446 ? 216.027 157.603 176.383 1.00 92.16  ? 446 GLY A O   1 
ATOM   5151 N N   . VAL B  1 447 ? 216.624 159.378 175.127 1.00 87.01  ? 447 VAL A N   1 
ATOM   5152 C CA  . VAL B  1 447 ? 216.713 160.267 176.280 1.00 87.33  ? 447 VAL A CA  1 
ATOM   5153 C C   . VAL B  1 447 ? 215.329 160.553 176.848 1.00 91.30  ? 447 VAL A C   1 
ATOM   5154 O O   . VAL B  1 447 ? 215.194 160.910 178.027 1.00 94.68  ? 447 VAL A O   1 
ATOM   5155 C CB  . VAL B  1 447 ? 217.449 161.564 175.895 1.00 86.71  ? 447 VAL A CB  1 
ATOM   5156 C CG1 . VAL B  1 447 ? 216.502 162.537 175.209 1.00 85.47  ? 447 VAL A CG1 1 
ATOM   5157 C CG2 . VAL B  1 447 ? 218.077 162.201 177.122 1.00 87.35  ? 447 VAL A CG2 1 
ATOM   5158 N N   . ARG B  1 448 ? 214.284 160.394 176.031 1.00 93.06  ? 448 ARG A N   1 
ATOM   5159 C CA  . ARG B  1 448 ? 212.928 160.643 176.503 1.00 87.25  ? 448 ARG A CA  1 
ATOM   5160 C C   . ARG B  1 448 ? 212.563 159.690 177.633 1.00 88.64  ? 448 ARG A C   1 
ATOM   5161 O O   . ARG B  1 448 ? 211.888 160.081 178.592 1.00 88.79  ? 448 ARG A O   1 
ATOM   5162 C CB  . ARG B  1 448 ? 211.944 160.518 175.339 1.00 87.66  ? 448 ARG A CB  1 
ATOM   5163 C CG  . ARG B  1 448 ? 210.491 160.402 175.748 1.00 85.87  ? 448 ARG A CG  1 
ATOM   5164 C CD  . ARG B  1 448 ? 209.992 161.729 176.302 1.00 85.51  ? 448 ARG A CD  1 
ATOM   5165 N NE  . ARG B  1 448 ? 210.282 162.868 175.436 1.00 87.65  ? 448 ARG A NE  1 
ATOM   5166 C CZ  . ARG B  1 448 ? 209.823 163.028 174.201 1.00 91.85  ? 448 ARG A CZ  1 
ATOM   5167 N NH1 . ARG B  1 448 ? 208.995 162.156 173.648 1.00 94.64  ? 448 ARG A NH1 1 
ATOM   5168 N NH2 . ARG B  1 448 ? 210.190 164.102 173.507 1.00 90.44  ? 448 ARG A NH2 1 
ATOM   5169 N N   . ALA B  1 449 ? 213.022 158.438 177.548 1.00 79.38  ? 449 ALA A N   1 
ATOM   5170 C CA  . ALA B  1 449 ? 212.815 157.499 178.646 1.00 75.95  ? 449 ALA A CA  1 
ATOM   5171 C C   . ALA B  1 449 ? 213.502 157.976 179.919 1.00 75.84  ? 449 ALA A C   1 
ATOM   5172 O O   . ALA B  1 449 ? 212.933 157.877 181.009 1.00 75.77  ? 449 ALA A O   1 
ATOM   5173 C CB  . ALA B  1 449 ? 213.317 156.111 178.253 1.00 79.18  ? 449 ALA A CB  1 
ATOM   5174 N N   . ILE B  1 450 ? 214.723 158.505 179.801 1.00 68.84  ? 450 ILE A N   1 
ATOM   5175 C CA  . ILE B  1 450 ? 215.425 159.041 180.967 1.00 72.36  ? 450 ILE A CA  1 
ATOM   5176 C C   . ILE B  1 450 ? 214.623 160.169 181.607 1.00 73.88  ? 450 ILE A C   1 
ATOM   5177 O O   . ILE B  1 450 ? 214.395 160.182 182.828 1.00 76.33  ? 450 ILE A O   1 
ATOM   5178 C CB  . ILE B  1 450 ? 216.835 159.517 180.570 1.00 71.37  ? 450 ILE A CB  1 
ATOM   5179 C CG1 . ILE B  1 450 ? 217.819 158.353 180.536 1.00 63.96  ? 450 ILE A CG1 1 
ATOM   5180 C CG2 . ILE B  1 450 ? 217.336 160.568 181.540 1.00 73.79  ? 450 ILE A CG2 1 
ATOM   5181 C CD1 . ILE B  1 450 ? 217.850 157.568 181.827 1.00 68.17  ? 450 ILE A CD1 1 
ATOM   5182 N N   . VAL B  1 451 ? 214.197 161.140 180.793 1.00 60.95  ? 451 VAL A N   1 
ATOM   5183 C CA  . VAL B  1 451 ? 213.520 162.314 181.337 1.00 60.01  ? 451 VAL A CA  1 
ATOM   5184 C C   . VAL B  1 451 ? 212.142 161.953 181.865 1.00 65.45  ? 451 VAL A C   1 
ATOM   5185 O O   . VAL B  1 451 ? 211.598 162.651 182.729 1.00 73.03  ? 451 VAL A O   1 
ATOM   5186 C CB  . VAL B  1 451 ? 213.459 163.443 180.294 1.00 66.77  ? 451 VAL A CB  1 
ATOM   5187 C CG1 . VAL B  1 451 ? 214.792 163.554 179.577 1.00 68.04  ? 451 VAL A CG1 1 
ATOM   5188 C CG2 . VAL B  1 451 ? 212.330 163.199 179.305 1.00 72.75  ? 451 VAL A CG2 1 
ATOM   5189 N N   . GLN B  1 452 ? 211.554 160.870 181.365 1.00 65.25  ? 452 GLN A N   1 
ATOM   5190 C CA  . GLN B  1 452 ? 210.284 160.409 181.905 1.00 64.95  ? 452 GLN A CA  1 
ATOM   5191 C C   . GLN B  1 452 ? 210.489 159.568 183.158 1.00 66.35  ? 452 GLN A C   1 
ATOM   5192 O O   . GLN B  1 452 ? 209.581 159.457 183.991 1.00 65.73  ? 452 GLN A O   1 
ATOM   5193 C CB  . GLN B  1 452 ? 209.542 159.635 180.818 1.00 63.03  ? 452 GLN A CB  1 
ATOM   5194 C CG  . GLN B  1 452 ? 208.574 158.589 181.289 1.00 66.26  ? 452 GLN A CG  1 
ATOM   5195 C CD  . GLN B  1 452 ? 207.637 158.177 180.186 1.00 71.54  ? 452 GLN A CD  1 
ATOM   5196 O OE1 . GLN B  1 452 ? 207.992 158.207 179.010 1.00 72.24  ? 452 GLN A OE1 1 
ATOM   5197 N NE2 . GLN B  1 452 ? 206.427 157.807 180.554 1.00 71.07  ? 452 GLN A NE2 1 
ATOM   5198 N N   . CYS B  1 453 ? 211.682 159.003 183.326 1.00 66.35  ? 453 CYS A N   1 
ATOM   5199 C CA  . CYS B  1 453 ? 211.934 158.027 184.371 1.00 59.13  ? 453 CYS A CA  1 
ATOM   5200 C C   . CYS B  1 453 ? 212.601 158.601 185.615 1.00 63.94  ? 453 CYS A C   1 
ATOM   5201 O O   . CYS B  1 453 ? 212.607 157.922 186.646 1.00 63.97  ? 453 CYS A O   1 
ATOM   5202 C CB  . CYS B  1 453 ? 212.794 156.893 183.809 1.00 56.15  ? 453 CYS A CB  1 
ATOM   5203 S SG  . CYS B  1 453 ? 212.484 155.291 184.548 1.00 69.31  ? 453 CYS A SG  1 
ATOM   5204 N N   . ILE B  1 454 ? 213.180 159.811 185.559 1.00 62.89  ? 454 ILE A N   1 
ATOM   5205 C CA  . ILE B  1 454 ? 213.679 160.434 186.797 1.00 58.22  ? 454 ILE A CA  1 
ATOM   5206 C C   . ILE B  1 454 ? 212.623 160.504 187.897 1.00 61.70  ? 454 ILE A C   1 
ATOM   5207 O O   . ILE B  1 454 ? 212.964 160.241 189.062 1.00 62.33  ? 454 ILE A O   1 
ATOM   5208 C CB  . ILE B  1 454 ? 214.300 161.815 186.520 1.00 56.98  ? 454 ILE A CB  1 
ATOM   5209 C CG1 . ILE B  1 454 ? 215.400 161.796 185.463 1.00 65.56  ? 454 ILE A CG1 1 
ATOM   5210 C CG2 . ILE B  1 454 ? 214.837 162.428 187.805 1.00 57.23  ? 454 ILE A CG2 1 
ATOM   5211 C CD1 . ILE B  1 454 ? 215.100 162.658 184.295 1.00 62.95  ? 454 ILE A CD1 1 
ATOM   5212 N N   . PRO B  1 455 ? 211.364 160.878 187.629 1.00 55.58  ? 455 PRO A N   1 
ATOM   5213 C CA  . PRO B  1 455 ? 210.409 161.013 188.745 1.00 50.20  ? 455 PRO A CA  1 
ATOM   5214 C C   . PRO B  1 455 ? 210.223 159.745 189.560 1.00 55.91  ? 455 PRO A C   1 
ATOM   5215 O O   . PRO B  1 455 ? 209.941 159.834 190.761 1.00 48.91  ? 455 PRO A O   1 
ATOM   5216 C CB  . PRO B  1 455 ? 209.111 161.430 188.043 1.00 52.22  ? 455 PRO A CB  1 
ATOM   5217 C CG  . PRO B  1 455 ? 209.559 162.094 186.808 1.00 55.55  ? 455 PRO A CG  1 
ATOM   5218 C CD  . PRO B  1 455 ? 210.762 161.334 186.362 1.00 50.58  ? 455 PRO A CD  1 
ATOM   5219 N N   . ALA B  1 456 ? 210.367 158.567 188.950 1.00 58.77  ? 456 ALA A N   1 
ATOM   5220 C CA  . ALA B  1 456 ? 210.323 157.328 189.719 1.00 50.98  ? 456 ALA A CA  1 
ATOM   5221 C C   . ALA B  1 456 ? 211.695 156.943 190.252 1.00 50.13  ? 456 ALA A C   1 
ATOM   5222 O O   . ALA B  1 456 ? 211.791 156.316 191.314 1.00 63.06  ? 456 ALA A O   1 
ATOM   5223 C CB  . ALA B  1 456 ? 209.759 156.195 188.864 1.00 50.38  ? 456 ALA A CB  1 
ATOM   5224 N N   . TRP B  1 457 ? 212.758 157.303 189.531 1.00 42.22  ? 457 TRP A N   1 
ATOM   5225 C CA  . TRP B  1 457 ? 214.109 156.986 189.981 1.00 42.76  ? 457 TRP A CA  1 
ATOM   5226 C C   . TRP B  1 457 ? 214.431 157.690 191.291 1.00 48.02  ? 457 TRP A C   1 
ATOM   5227 O O   . TRP B  1 457 ? 215.082 157.114 192.170 1.00 55.90  ? 457 TRP A O   1 
ATOM   5228 C CB  . TRP B  1 457 ? 215.116 157.368 188.896 1.00 55.62  ? 457 TRP A CB  1 
ATOM   5229 C CG  . TRP B  1 457 ? 216.501 157.617 189.397 1.00 55.06  ? 457 TRP A CG  1 
ATOM   5230 C CD1 . TRP B  1 457 ? 217.017 158.803 189.829 1.00 54.98  ? 457 TRP A CD1 1 
ATOM   5231 C CD2 . TRP B  1 457 ? 217.558 156.659 189.499 1.00 49.56  ? 457 TRP A CD2 1 
ATOM   5232 N NE1 . TRP B  1 457 ? 218.327 158.640 190.205 1.00 51.96  ? 457 TRP A NE1 1 
ATOM   5233 C CE2 . TRP B  1 457 ? 218.684 157.332 190.010 1.00 51.90  ? 457 TRP A CE2 1 
ATOM   5234 C CE3 . TRP B  1 457 ? 217.661 155.295 189.212 1.00 47.85  ? 457 TRP A CE3 1 
ATOM   5235 C CZ2 . TRP B  1 457 ? 219.895 156.689 190.240 1.00 56.86  ? 457 TRP A CZ2 1 
ATOM   5236 C CZ3 . TRP B  1 457 ? 218.863 154.659 189.442 1.00 54.22  ? 457 TRP A CZ3 1 
ATOM   5237 C CH2 . TRP B  1 457 ? 219.965 155.356 189.950 1.00 56.02  ? 457 TRP A CH2 1 
ATOM   5238 N N   . LEU B  1 458 ? 213.992 158.941 191.434 1.00 51.15  ? 458 LEU A N   1 
ATOM   5239 C CA  . LEU B  1 458 ? 214.238 159.676 192.670 1.00 50.50  ? 458 LEU A CA  1 
ATOM   5240 C C   . LEU B  1 458 ? 213.579 158.989 193.856 1.00 54.57  ? 458 LEU A C   1 
ATOM   5241 O O   . LEU B  1 458 ? 214.191 158.851 194.921 1.00 59.64  ? 458 LEU A O   1 
ATOM   5242 C CB  . LEU B  1 458 ? 213.734 161.112 192.536 1.00 40.57  ? 458 LEU A CB  1 
ATOM   5243 C CG  . LEU B  1 458 ? 214.450 161.978 191.502 1.00 49.65  ? 458 LEU A CG  1 
ATOM   5244 C CD1 . LEU B  1 458 ? 213.691 163.272 191.276 1.00 56.45  ? 458 LEU A CD1 1 
ATOM   5245 C CD2 . LEU B  1 458 ? 215.875 162.259 191.939 1.00 52.33  ? 458 LEU A CD2 1 
ATOM   5246 N N   . ARG B  1 459 ? 212.335 158.536 193.689 1.00 49.31  ? 459 ARG A N   1 
ATOM   5247 C CA  . ARG B  1 459 ? 211.657 157.841 194.778 1.00 48.04  ? 459 ARG A CA  1 
ATOM   5248 C C   . ARG B  1 459 ? 212.303 156.492 195.063 1.00 53.26  ? 459 ARG A C   1 
ATOM   5249 O O   . ARG B  1 459 ? 212.397 156.077 196.223 1.00 57.73  ? 459 ARG A O   1 
ATOM   5250 C CB  . ARG B  1 459 ? 210.175 157.670 194.454 1.00 39.74  ? 459 ARG A CB  1 
ATOM   5251 C CG  . ARG B  1 459 ? 209.291 158.707 195.111 1.00 39.50  ? 459 ARG A CG  1 
ATOM   5252 C CD  . ARG B  1 459 ? 209.683 158.897 196.562 1.00 40.93  ? 459 ARG A CD  1 
ATOM   5253 N NE  . ARG B  1 459 ? 209.101 157.889 197.437 1.00 43.18  ? 459 ARG A NE  1 
ATOM   5254 C CZ  . ARG B  1 459 ? 209.473 157.693 198.693 1.00 47.21  ? 459 ARG A CZ  1 
ATOM   5255 N NH1 . ARG B  1 459 ? 210.440 158.404 199.246 1.00 55.80  ? 459 ARG A NH1 1 
ATOM   5256 N NH2 . ARG B  1 459 ? 208.855 156.765 199.416 1.00 45.93  ? 459 ARG A NH2 1 
ATOM   5257 N N   . PHE B  1 460 ? 212.752 155.791 194.021 1.00 52.85  ? 460 PHE A N   1 
ATOM   5258 C CA  . PHE B  1 460 ? 213.442 154.522 194.227 1.00 50.78  ? 460 PHE A CA  1 
ATOM   5259 C C   . PHE B  1 460 ? 214.709 154.721 195.050 1.00 49.00  ? 460 PHE A C   1 
ATOM   5260 O O   . PHE B  1 460 ? 214.970 153.982 196.009 1.00 62.02  ? 460 PHE A O   1 
ATOM   5261 C CB  . PHE B  1 460 ? 213.761 153.890 192.872 1.00 51.16  ? 460 PHE A CB  1 
ATOM   5262 C CG  . PHE B  1 460 ? 214.680 152.708 192.948 1.00 47.02  ? 460 PHE A CG  1 
ATOM   5263 C CD1 . PHE B  1 460 ? 214.330 151.587 193.675 1.00 52.89  ? 460 PHE A CD1 1 
ATOM   5264 C CD2 . PHE B  1 460 ? 215.890 152.715 192.279 1.00 52.13  ? 460 PHE A CD2 1 
ATOM   5265 C CE1 . PHE B  1 460 ? 215.173 150.498 193.740 1.00 54.81  ? 460 PHE A CE1 1 
ATOM   5266 C CE2 . PHE B  1 460 ? 216.736 151.629 192.340 1.00 54.83  ? 460 PHE A CE2 1 
ATOM   5267 C CZ  . PHE B  1 460 ? 216.377 150.519 193.071 1.00 55.98  ? 460 PHE A CZ  1 
ATOM   5268 N N   . ILE B  1 461 ? 215.494 155.743 194.708 1.00 39.18  ? 461 ILE A N   1 
ATOM   5269 C CA  . ILE B  1 461 ? 216.735 156.000 195.430 1.00 46.97  ? 461 ILE A CA  1 
ATOM   5270 C C   . ILE B  1 461 ? 216.445 156.476 196.848 1.00 48.74  ? 461 ILE A C   1 
ATOM   5271 O O   . ILE B  1 461 ? 217.165 156.127 197.790 1.00 51.03  ? 461 ILE A O   1 
ATOM   5272 C CB  . ILE B  1 461 ? 217.608 157.002 194.656 1.00 51.59  ? 461 ILE A CB  1 
ATOM   5273 C CG1 . ILE B  1 461 ? 217.954 156.440 193.279 1.00 52.99  ? 461 ILE A CG1 1 
ATOM   5274 C CG2 . ILE B  1 461 ? 218.880 157.286 195.416 1.00 49.64  ? 461 ILE A CG2 1 
ATOM   5275 C CD1 . ILE B  1 461 ? 218.884 155.250 193.328 1.00 54.84  ? 461 ILE A CD1 1 
ATOM   5276 N N   . GLN B  1 462 ? 215.392 157.278 197.031 1.00 53.92  ? 462 GLN A N   1 
ATOM   5277 C CA  . GLN B  1 462 ? 215.024 157.703 198.378 1.00 56.90  ? 462 GLN A CA  1 
ATOM   5278 C C   . GLN B  1 462 ? 214.602 156.523 199.239 1.00 55.21  ? 462 GLN A C   1 
ATOM   5279 O O   . GLN B  1 462 ? 214.947 156.459 200.421 1.00 55.38  ? 462 GLN A O   1 
ATOM   5280 C CB  . GLN B  1 462 ? 213.911 158.746 198.324 1.00 47.06  ? 462 GLN A CB  1 
ATOM   5281 C CG  . GLN B  1 462 ? 214.383 160.098 197.872 1.00 46.61  ? 462 GLN A CG  1 
ATOM   5282 C CD  . GLN B  1 462 ? 213.294 161.136 197.903 1.00 55.97  ? 462 GLN A CD  1 
ATOM   5283 O OE1 . GLN B  1 462 ? 213.054 161.821 196.914 1.00 68.63  ? 462 GLN A OE1 1 
ATOM   5284 N NE2 . GLN B  1 462 ? 212.623 161.257 199.040 1.00 53.20  ? 462 GLN A NE2 1 
ATOM   5285 N N   . CYS B  1 463 ? 213.844 155.585 198.672 1.00 54.15  ? 463 CYS A N   1 
ATOM   5286 C CA  . CYS B  1 463 ? 213.454 154.402 199.430 1.00 54.37  ? 463 CYS A CA  1 
ATOM   5287 C C   . CYS B  1 463 ? 214.667 153.550 199.782 1.00 64.22  ? 463 CYS A C   1 
ATOM   5288 O O   . CYS B  1 463 ? 214.766 153.028 200.901 1.00 70.25  ? 463 CYS A O   1 
ATOM   5289 C CB  . CYS B  1 463 ? 212.431 153.592 198.638 1.00 52.60  ? 463 CYS A CB  1 
ATOM   5290 S SG  . CYS B  1 463 ? 210.738 154.164 198.860 1.00 72.73  ? 463 CYS A SG  1 
ATOM   5291 N N   . LEU B  1 464 ? 215.604 153.402 198.842 1.00 58.34  ? 464 LEU A N   1 
ATOM   5292 C CA  . LEU B  1 464 ? 216.826 152.663 199.143 1.00 48.29  ? 464 LEU A CA  1 
ATOM   5293 C C   . LEU B  1 464 ? 217.620 153.344 200.252 1.00 56.99  ? 464 LEU A C   1 
ATOM   5294 O O   . LEU B  1 464 ? 218.151 152.675 201.145 1.00 61.73  ? 464 LEU A O   1 
ATOM   5295 C CB  . LEU B  1 464 ? 217.679 152.516 197.886 1.00 48.88  ? 464 LEU A CB  1 
ATOM   5296 C CG  . LEU B  1 464 ? 217.220 151.459 196.882 1.00 47.71  ? 464 LEU A CG  1 
ATOM   5297 C CD1 . LEU B  1 464 ? 218.332 151.157 195.897 1.00 57.84  ? 464 LEU A CD1 1 
ATOM   5298 C CD2 . LEU B  1 464 ? 216.767 150.197 197.594 1.00 49.08  ? 464 LEU A CD2 1 
ATOM   5299 N N   . ARG B  1 465 ? 217.710 154.675 200.211 1.00 58.43  ? 465 ARG A N   1 
ATOM   5300 C CA  . ARG B  1 465 ? 218.410 155.408 201.261 1.00 60.13  ? 465 ARG A CA  1 
ATOM   5301 C C   . ARG B  1 465 ? 217.703 155.260 202.601 1.00 60.02  ? 465 ARG A C   1 
ATOM   5302 O O   . ARG B  1 465 ? 218.352 155.144 203.646 1.00 61.98  ? 465 ARG A O   1 
ATOM   5303 C CB  . ARG B  1 465 ? 218.536 156.881 200.877 1.00 57.95  ? 465 ARG A CB  1 
ATOM   5304 C CG  . ARG B  1 465 ? 218.838 157.805 202.043 1.00 55.74  ? 465 ARG A CG  1 
ATOM   5305 C CD  . ARG B  1 465 ? 220.268 157.633 202.522 1.00 63.57  ? 465 ARG A CD  1 
ATOM   5306 N NE  . ARG B  1 465 ? 220.436 158.057 203.906 1.00 65.16  ? 465 ARG A NE  1 
ATOM   5307 C CZ  . ARG B  1 465 ? 220.987 159.205 204.276 1.00 65.12  ? 465 ARG A CZ  1 
ATOM   5308 N NH1 . ARG B  1 465 ? 221.441 160.072 203.386 1.00 62.75  ? 465 ARG A NH1 1 
ATOM   5309 N NH2 . ARG B  1 465 ? 221.086 159.489 205.571 1.00 61.98  ? 465 ARG A NH2 1 
ATOM   5310 N N   . ARG B  1 466 ? 216.369 155.268 202.590 1.00 65.34  ? 466 ARG A N   1 
ATOM   5311 C CA  . ARG B  1 466 ? 215.615 155.055 203.819 1.00 67.55  ? 466 ARG A CA  1 
ATOM   5312 C C   . ARG B  1 466 ? 215.922 153.691 204.415 1.00 65.51  ? 466 ARG A C   1 
ATOM   5313 O O   . ARG B  1 466 ? 216.144 153.569 205.626 1.00 70.04  ? 466 ARG A O   1 
ATOM   5314 C CB  . ARG B  1 466 ? 214.117 155.187 203.548 1.00 64.23  ? 466 ARG A CB  1 
ATOM   5315 C CG  . ARG B  1 466 ? 213.644 156.594 203.268 1.00 63.80  ? 466 ARG A CG  1 
ATOM   5316 C CD  . ARG B  1 466 ? 212.168 156.745 203.583 1.00 60.88  ? 466 ARG A CD  1 
ATOM   5317 N NE  . ARG B  1 466 ? 211.947 157.031 204.995 1.00 60.08  ? 466 ARG A NE  1 
ATOM   5318 C CZ  . ARG B  1 466 ? 211.001 156.469 205.733 1.00 66.37  ? 466 ARG A CZ  1 
ATOM   5319 N NH1 . ARG B  1 466 ? 210.169 155.575 205.226 1.00 70.42  ? 466 ARG A NH1 1 
ATOM   5320 N NH2 . ARG B  1 466 ? 210.888 156.811 207.013 1.00 64.50  ? 466 ARG A NH2 1 
ATOM   5321 N N   . TYR B  1 467 ? 215.945 152.652 203.577 1.00 66.70  ? 467 TYR A N   1 
ATOM   5322 C CA  . TYR B  1 467 ? 216.288 151.321 204.070 1.00 70.38  ? 467 TYR A CA  1 
ATOM   5323 C C   . TYR B  1 467 ? 217.709 151.289 204.615 1.00 71.97  ? 467 TYR A C   1 
ATOM   5324 O O   . TYR B  1 467 ? 217.965 150.723 205.683 1.00 75.06  ? 467 TYR A O   1 
ATOM   5325 C CB  . TYR B  1 467 ? 216.122 150.279 202.966 1.00 72.98  ? 467 TYR A CB  1 
ATOM   5326 C CG  . TYR B  1 467 ? 216.870 148.996 203.253 1.00 75.68  ? 467 TYR A CG  1 
ATOM   5327 C CD1 . TYR B  1 467 ? 216.532 148.202 204.341 1.00 72.40  ? 467 TYR A CD1 1 
ATOM   5328 C CD2 . TYR B  1 467 ? 217.913 148.581 202.440 1.00 74.62  ? 467 TYR A CD2 1 
ATOM   5329 C CE1 . TYR B  1 467 ? 217.210 147.032 204.609 1.00 70.57  ? 467 TYR A CE1 1 
ATOM   5330 C CE2 . TYR B  1 467 ? 218.598 147.410 202.700 1.00 76.96  ? 467 TYR A CE2 1 
ATOM   5331 C CZ  . TYR B  1 467 ? 218.242 146.640 203.786 1.00 77.58  ? 467 TYR A CZ  1 
ATOM   5332 O OH  . TYR B  1 467 ? 218.922 145.474 204.050 1.00 77.80  ? 467 TYR A OH  1 
ATOM   5333 N N   . ARG B  1 468 ? 218.651 151.896 203.890 1.00 67.21  ? 468 ARG A N   1 
ATOM   5334 C CA  . ARG B  1 468 ? 220.037 151.919 204.343 1.00 71.64  ? 468 ARG A CA  1 
ATOM   5335 C C   . ARG B  1 468 ? 220.174 152.639 205.678 1.00 74.11  ? 468 ARG A C   1 
ATOM   5336 O O   . ARG B  1 468 ? 221.008 152.259 206.507 1.00 77.23  ? 468 ARG A O   1 
ATOM   5337 C CB  . ARG B  1 468 ? 220.914 152.572 203.273 1.00 70.29  ? 468 ARG A CB  1 
ATOM   5338 C CG  . ARG B  1 468 ? 222.180 153.237 203.782 1.00 71.90  ? 468 ARG A CG  1 
ATOM   5339 C CD  . ARG B  1 468 ? 222.775 154.141 202.713 1.00 73.78  ? 468 ARG A CD  1 
ATOM   5340 N NE  . ARG B  1 468 ? 222.610 153.576 201.378 1.00 79.53  ? 468 ARG A NE  1 
ATOM   5341 C CZ  . ARG B  1 468 ? 222.658 154.277 200.253 1.00 74.12  ? 468 ARG A CZ  1 
ATOM   5342 N NH1 . ARG B  1 468 ? 222.881 155.581 200.261 1.00 67.73  ? 468 ARG A NH1 1 
ATOM   5343 N NH2 . ARG B  1 468 ? 222.480 153.654 199.092 1.00 69.67  ? 468 ARG A NH2 1 
ATOM   5344 N N   . ASP B  1 469 ? 219.355 153.665 205.908 1.00 78.62  ? 469 ASP A N   1 
ATOM   5345 C CA  . ASP B  1 469 ? 219.411 154.399 207.167 1.00 79.94  ? 469 ASP A CA  1 
ATOM   5346 C C   . ASP B  1 469 ? 218.753 153.629 208.306 1.00 78.58  ? 469 ASP A C   1 
ATOM   5347 O O   . ASP B  1 469 ? 219.228 153.685 209.446 1.00 78.93  ? 469 ASP A O   1 
ATOM   5348 C CB  . ASP B  1 469 ? 218.751 155.767 207.002 1.00 78.62  ? 469 ASP A CB  1 
ATOM   5349 C CG  . ASP B  1 469 ? 219.408 156.835 207.849 1.00 82.89  ? 469 ASP A CG  1 
ATOM   5350 O OD1 . ASP B  1 469 ? 219.660 156.574 209.045 1.00 81.20  ? 469 ASP A OD1 1 
ATOM   5351 O OD2 . ASP B  1 469 ? 219.677 157.934 207.319 1.00 82.08  ? 469 ASP A OD2 1 
ATOM   5352 N N   . THR B  1 470 ? 217.663 152.912 208.028 1.00 81.97  ? 470 THR A N   1 
ATOM   5353 C CA  . THR B  1 470 ? 216.919 152.236 209.084 1.00 84.30  ? 470 THR A CA  1 
ATOM   5354 C C   . THR B  1 470 ? 217.170 150.736 209.150 1.00 82.74  ? 470 THR A C   1 
ATOM   5355 O O   . THR B  1 470 ? 216.834 150.118 210.167 1.00 81.58  ? 470 THR A O   1 
ATOM   5356 C CB  . THR B  1 470 ? 215.414 152.475 208.921 1.00 80.99  ? 470 THR A CB  1 
ATOM   5357 O OG1 . THR B  1 470 ? 214.735 152.071 210.116 1.00 80.33  ? 470 THR A OG1 1 
ATOM   5358 C CG2 . THR B  1 470 ? 214.874 151.667 207.759 1.00 80.17  ? 470 THR A CG2 1 
ATOM   5359 N N   . LYS B  1 471 ? 217.743 150.141 208.102 1.00 86.57  ? 471 LYS A N   1 
ATOM   5360 C CA  . LYS B  1 471 ? 218.017 148.702 208.056 1.00 89.42  ? 471 LYS A CA  1 
ATOM   5361 C C   . LYS B  1 471 ? 216.749 147.883 208.293 1.00 90.30  ? 471 LYS A C   1 
ATOM   5362 O O   . LYS B  1 471 ? 216.768 146.854 208.971 1.00 92.27  ? 471 LYS A O   1 
ATOM   5363 C CB  . LYS B  1 471 ? 219.115 148.320 209.051 1.00 88.12  ? 471 LYS A CB  1 
ATOM   5364 C CG  . LYS B  1 471 ? 220.438 149.021 208.786 1.00 88.50  ? 471 LYS A CG  1 
ATOM   5365 C CD  . LYS B  1 471 ? 221.392 148.888 209.960 1.00 92.72  ? 471 LYS A CD  1 
ATOM   5366 C CE  . LYS B  1 471 ? 222.644 149.725 209.744 1.00 91.05  ? 471 LYS A CE  1 
ATOM   5367 N NZ  . LYS B  1 471 ? 223.570 149.657 210.907 1.00 90.53  ? 471 LYS A NZ  1 
ATOM   5368 N N   . ARG B  1 472 ? 215.635 148.347 207.728 1.00 87.40  ? 472 ARG A N   1 
ATOM   5369 C CA  . ARG B  1 472 ? 214.355 147.648 207.783 1.00 85.98  ? 472 ARG A CA  1 
ATOM   5370 C C   . ARG B  1 472 ? 213.959 147.280 206.359 1.00 83.05  ? 472 ARG A C   1 
ATOM   5371 O O   . ARG B  1 472 ? 213.700 148.163 205.536 1.00 78.01  ? 472 ARG A O   1 
ATOM   5372 C CB  . ARG B  1 472 ? 213.279 148.511 208.440 1.00 82.78  ? 472 ARG A CB  1 
ATOM   5373 C CG  . ARG B  1 472 ? 213.379 148.599 209.952 1.00 80.73  ? 472 ARG A CG  1 
ATOM   5374 C CD  . ARG B  1 472 ? 212.154 149.280 210.543 1.00 83.19  ? 472 ARG A CD  1 
ATOM   5375 N NE  . ARG B  1 472 ? 210.912 148.701 210.045 1.00 86.78  ? 472 ARG A NE  1 
ATOM   5376 C CZ  . ARG B  1 472 ? 209.772 148.678 210.722 1.00 85.93  ? 472 ARG A CZ  1 
ATOM   5377 N NH1 . ARG B  1 472 ? 209.679 149.195 211.936 1.00 84.54  ? 472 ARG A NH1 1 
ATOM   5378 N NH2 . ARG B  1 472 ? 208.699 148.122 210.167 1.00 81.30  ? 472 ARG A NH2 1 
ATOM   5379 N N   . ALA B  1 473 ? 213.910 145.977 206.073 1.00 78.98  ? 473 ALA A N   1 
ATOM   5380 C CA  . ALA B  1 473 ? 213.554 145.529 204.731 1.00 78.78  ? 473 ALA A CA  1 
ATOM   5381 C C   . ALA B  1 473 ? 212.157 145.997 204.350 1.00 77.14  ? 473 ALA A C   1 
ATOM   5382 O O   . ALA B  1 473 ? 211.910 146.372 203.199 1.00 77.73  ? 473 ALA A O   1 
ATOM   5383 C CB  . ALA B  1 473 ? 213.655 144.007 204.640 1.00 79.78  ? 473 ALA A CB  1 
ATOM   5384 N N   . PHE B  1 474 ? 211.233 145.977 205.300 1.00 73.45  ? 474 PHE A N   1 
ATOM   5385 C CA  . PHE B  1 474 ? 209.870 146.469 205.198 1.00 72.31  ? 474 PHE A CA  1 
ATOM   5386 C C   . PHE B  1 474 ? 209.722 147.757 205.996 1.00 70.28  ? 474 PHE A C   1 
ATOM   5387 O O   . PHE B  1 474 ? 210.277 147.871 207.094 1.00 72.50  ? 474 PHE A O   1 
ATOM   5388 C CB  . PHE B  1 474 ? 208.884 145.425 205.725 1.00 72.89  ? 474 PHE A CB  1 
ATOM   5389 C CG  . PHE B  1 474 ? 207.451 145.712 205.387 1.00 69.98  ? 474 PHE A CG  1 
ATOM   5390 C CD1 . PHE B  1 474 ? 206.962 145.457 204.119 1.00 71.28  ? 474 PHE A CD1 1 
ATOM   5391 C CD2 . PHE B  1 474 ? 206.591 146.228 206.340 1.00 71.88  ? 474 PHE A CD2 1 
ATOM   5392 C CE1 . PHE B  1 474 ? 205.645 145.717 203.804 1.00 73.57  ? 474 PHE A CE1 1 
ATOM   5393 C CE2 . PHE B  1 474 ? 205.271 146.490 206.030 1.00 75.69  ? 474 PHE A CE2 1 
ATOM   5394 C CZ  . PHE B  1 474 ? 204.799 146.232 204.761 1.00 73.95  ? 474 PHE A CZ  1 
ATOM   5395 N N   . PRO B  1 475 ? 208.989 148.755 205.491 1.00 69.87  ? 475 PRO A N   1 
ATOM   5396 C CA  . PRO B  1 475 ? 208.286 148.808 204.206 1.00 69.67  ? 475 PRO A CA  1 
ATOM   5397 C C   . PRO B  1 475 ? 209.046 149.564 203.125 1.00 66.75  ? 475 PRO A C   1 
ATOM   5398 O O   . PRO B  1 475 ? 208.438 150.282 202.340 1.00 68.13  ? 475 PRO A O   1 
ATOM   5399 C CB  . PRO B  1 475 ? 207.000 149.538 204.580 1.00 71.86  ? 475 PRO A CB  1 
ATOM   5400 C CG  . PRO B  1 475 ? 207.465 150.552 205.596 1.00 69.04  ? 475 PRO A CG  1 
ATOM   5401 C CD  . PRO B  1 475 ? 208.613 149.897 206.344 1.00 73.31  ? 475 PRO A CD  1 
ATOM   5402 N N   . HIS B  1 476 ? 210.367 149.430 203.047 1.00 65.65  ? 476 HIS A N   1 
ATOM   5403 C CA  . HIS B  1 476 ? 211.166 150.241 202.138 1.00 61.86  ? 476 HIS A CA  1 
ATOM   5404 C C   . HIS B  1 476 ? 211.566 149.508 200.866 1.00 64.35  ? 476 HIS A C   1 
ATOM   5405 O O   . HIS B  1 476 ? 211.603 150.121 199.796 1.00 64.72  ? 476 HIS A O   1 
ATOM   5406 C CB  . HIS B  1 476 ? 212.416 150.753 202.857 1.00 61.61  ? 476 HIS A CB  1 
ATOM   5407 C CG  . HIS B  1 476 ? 212.117 151.591 204.062 1.00 63.04  ? 476 HIS A CG  1 
ATOM   5408 N ND1 . HIS B  1 476 ? 213.068 152.372 204.680 1.00 66.71  ? 476 HIS A ND1 1 
ATOM   5409 C CD2 . HIS B  1 476 ? 210.968 151.783 204.752 1.00 61.35  ? 476 HIS A CD2 1 
ATOM   5410 C CE1 . HIS B  1 476 ? 212.522 153.001 205.705 1.00 65.95  ? 476 HIS A CE1 1 
ATOM   5411 N NE2 . HIS B  1 476 ? 211.248 152.660 205.771 1.00 61.35  ? 476 HIS A NE2 1 
ATOM   5412 N N   . LEU B  1 477 ? 211.864 148.209 200.943 1.00 60.13  ? 477 LEU A N   1 
ATOM   5413 C CA  . LEU B  1 477 ? 212.189 147.469 199.728 1.00 56.39  ? 477 LEU A CA  1 
ATOM   5414 C C   . LEU B  1 477 ? 210.943 147.189 198.897 1.00 63.77  ? 477 LEU A C   1 
ATOM   5415 O O   . LEU B  1 477 ? 211.009 147.172 197.664 1.00 73.85  ? 477 LEU A O   1 
ATOM   5416 C CB  . LEU B  1 477 ? 212.916 146.169 200.066 1.00 63.81  ? 477 LEU A CB  1 
ATOM   5417 C CG  . LEU B  1 477 ? 214.427 146.286 200.279 1.00 64.79  ? 477 LEU A CG  1 
ATOM   5418 C CD1 . LEU B  1 477 ? 215.064 147.089 199.155 1.00 61.86  ? 477 LEU A CD1 1 
ATOM   5419 C CD2 . LEU B  1 477 ? 214.751 146.900 201.621 1.00 60.49  ? 477 LEU A CD2 1 
ATOM   5420 N N   . VAL B  1 478 ? 209.800 146.968 199.546 1.00 54.45  ? 478 VAL A N   1 
ATOM   5421 C CA  . VAL B  1 478 ? 208.550 146.829 198.803 1.00 53.31  ? 478 VAL A CA  1 
ATOM   5422 C C   . VAL B  1 478 ? 208.244 148.117 198.050 1.00 57.03  ? 478 VAL A C   1 
ATOM   5423 O O   . VAL B  1 478 ? 207.855 148.097 196.876 1.00 57.82  ? 478 VAL A O   1 
ATOM   5424 C CB  . VAL B  1 478 ? 207.403 146.445 199.755 1.00 54.52  ? 478 VAL A CB  1 
ATOM   5425 C CG1 . VAL B  1 478 ? 206.232 145.875 198.977 1.00 55.60  ? 478 VAL A CG1 1 
ATOM   5426 C CG2 . VAL B  1 478 ? 207.887 145.461 200.798 1.00 56.11  ? 478 VAL A CG2 1 
ATOM   5427 N N   . ASN B  1 479 ? 208.426 149.258 198.717 1.00 61.34  ? 479 ASN A N   1 
ATOM   5428 C CA  . ASN B  1 479 ? 208.230 150.551 198.070 1.00 57.63  ? 479 ASN A CA  1 
ATOM   5429 C C   . ASN B  1 479 ? 209.229 150.763 196.938 1.00 60.26  ? 479 ASN A C   1 
ATOM   5430 O O   . ASN B  1 479 ? 208.879 151.304 195.881 1.00 69.52  ? 479 ASN A O   1 
ATOM   5431 C CB  . ASN B  1 479 ? 208.345 151.661 199.112 1.00 49.42  ? 479 ASN A CB  1 
ATOM   5432 C CG  . ASN B  1 479 ? 207.449 152.836 198.813 1.00 49.33  ? 479 ASN A CG  1 
ATOM   5433 O OD1 . ASN B  1 479 ? 206.338 152.675 198.314 1.00 59.03  ? 479 ASN A OD1 1 
ATOM   5434 N ND2 . ASN B  1 479 ? 207.926 154.031 199.126 1.00 50.34  ? 479 ASN A ND2 1 
ATOM   5435 N N   . ALA B  1 480 ? 210.483 150.354 197.145 1.00 54.05  ? 480 ALA A N   1 
ATOM   5436 C CA  . ALA B  1 480 ? 211.485 150.474 196.092 1.00 53.57  ? 480 ALA A CA  1 
ATOM   5437 C C   . ALA B  1 480 ? 211.110 149.630 194.881 1.00 46.35  ? 480 ALA A C   1 
ATOM   5438 O O   . ALA B  1 480 ? 211.295 150.056 193.738 1.00 49.04  ? 480 ALA A O   1 
ATOM   5439 C CB  . ALA B  1 480 ? 212.859 150.072 196.625 1.00 53.14  ? 480 ALA A CB  1 
ATOM   5440 N N   . GLY B  1 481 ? 210.585 148.428 195.113 1.00 47.84  ? 481 GLY A N   1 
ATOM   5441 C CA  . GLY B  1 481 ? 210.088 147.625 194.010 1.00 57.78  ? 481 GLY A CA  1 
ATOM   5442 C C   . GLY B  1 481 ? 208.920 148.281 193.299 1.00 58.73  ? 481 GLY A C   1 
ATOM   5443 O O   . GLY B  1 481 ? 208.837 148.259 192.067 1.00 62.89  ? 481 GLY A O   1 
ATOM   5444 N N   . LYS B  1 482 ? 208.007 148.880 194.067 1.00 62.65  ? 482 LYS A N   1 
ATOM   5445 C CA  . LYS B  1 482 ? 206.873 149.581 193.473 1.00 62.29  ? 482 LYS A CA  1 
ATOM   5446 C C   . LYS B  1 482 ? 207.346 150.701 192.559 1.00 63.84  ? 482 LYS A C   1 
ATOM   5447 O O   . LYS B  1 482 ? 206.817 150.888 191.457 1.00 60.27  ? 482 LYS A O   1 
ATOM   5448 C CB  . LYS B  1 482 ? 205.970 150.136 194.573 1.00 58.91  ? 482 LYS A CB  1 
ATOM   5449 C CG  . LYS B  1 482 ? 205.256 151.422 194.203 1.00 52.47  ? 482 LYS A CG  1 
ATOM   5450 C CD  . LYS B  1 482 ? 204.256 151.806 195.270 1.00 64.71  ? 482 LYS A CD  1 
ATOM   5451 C CE  . LYS B  1 482 ? 203.615 153.148 194.982 1.00 68.44  ? 482 LYS A CE  1 
ATOM   5452 N NZ  . LYS B  1 482 ? 204.534 154.273 195.287 1.00 62.54  ? 482 LYS A NZ  1 
ATOM   5453 N N   . TYR B  1 483 ? 208.349 151.457 193.003 1.00 61.73  ? 483 TYR A N   1 
ATOM   5454 C CA  . TYR B  1 483 ? 208.862 152.552 192.191 1.00 49.03  ? 483 TYR A CA  1 
ATOM   5455 C C   . TYR B  1 483 ? 209.721 152.068 191.032 1.00 53.24  ? 483 TYR A C   1 
ATOM   5456 O O   . TYR B  1 483 ? 209.796 152.754 190.008 1.00 60.78  ? 483 TYR A O   1 
ATOM   5457 C CB  . TYR B  1 483 ? 209.648 153.524 193.066 1.00 41.06  ? 483 TYR A CB  1 
ATOM   5458 C CG  . TYR B  1 483 ? 208.752 154.409 193.893 1.00 45.36  ? 483 TYR A CG  1 
ATOM   5459 C CD1 . TYR B  1 483 ? 207.835 155.251 193.288 1.00 51.71  ? 483 TYR A CD1 1 
ATOM   5460 C CD2 . TYR B  1 483 ? 208.809 154.390 195.276 1.00 49.36  ? 483 TYR A CD2 1 
ATOM   5461 C CE1 . TYR B  1 483 ? 207.010 156.057 194.035 1.00 53.11  ? 483 TYR A CE1 1 
ATOM   5462 C CE2 . TYR B  1 483 ? 207.985 155.193 196.032 1.00 52.85  ? 483 TYR A CE2 1 
ATOM   5463 C CZ  . TYR B  1 483 ? 207.088 156.025 195.406 1.00 54.85  ? 483 TYR A CZ  1 
ATOM   5464 O OH  . TYR B  1 483 ? 206.262 156.830 196.154 1.00 59.85  ? 483 TYR A OH  1 
ATOM   5465 N N   . SER B  1 484 ? 210.367 150.909 191.163 1.00 62.29  ? 484 SER A N   1 
ATOM   5466 C CA  . SER B  1 484 ? 211.179 150.378 190.077 1.00 65.33  ? 484 SER A CA  1 
ATOM   5467 C C   . SER B  1 484 ? 210.356 149.650 189.026 1.00 60.64  ? 484 SER A C   1 
ATOM   5468 O O   . SER B  1 484 ? 210.877 149.369 187.942 1.00 58.12  ? 484 SER A O   1 
ATOM   5469 C CB  . SER B  1 484 ? 212.253 149.436 190.622 1.00 68.62  ? 484 SER A CB  1 
ATOM   5470 O OG  . SER B  1 484 ? 211.782 148.718 191.743 1.00 73.32  ? 484 SER A OG  1 
ATOM   5471 N N   . THR B  1 485 ? 209.097 149.319 189.326 1.00 62.64  ? 485 THR A N   1 
ATOM   5472 C CA  . THR B  1 485 ? 208.216 148.818 188.275 1.00 63.33  ? 485 THR A CA  1 
ATOM   5473 C C   . THR B  1 485 ? 208.135 149.795 187.109 1.00 64.85  ? 485 THR A C   1 
ATOM   5474 O O   . THR B  1 485 ? 208.015 149.374 185.952 1.00 69.09  ? 485 THR A O   1 
ATOM   5475 C CB  . THR B  1 485 ? 206.814 148.552 188.822 1.00 64.14  ? 485 THR A CB  1 
ATOM   5476 O OG1 . THR B  1 485 ? 206.284 149.755 189.391 1.00 70.53  ? 485 THR A OG1 1 
ATOM   5477 C CG2 . THR B  1 485 ? 206.839 147.459 189.870 1.00 68.08  ? 485 THR A CG2 1 
ATOM   5478 N N   . THR B  1 486 ? 208.205 151.097 187.396 1.00 60.43  ? 486 THR A N   1 
ATOM   5479 C CA  . THR B  1 486 ? 208.182 152.103 186.340 1.00 62.12  ? 486 THR A CA  1 
ATOM   5480 C C   . THR B  1 486 ? 209.398 151.975 185.430 1.00 62.53  ? 486 THR A C   1 
ATOM   5481 O O   . THR B  1 486 ? 209.306 152.223 184.221 1.00 68.60  ? 486 THR A O   1 
ATOM   5482 C CB  . THR B  1 486 ? 208.108 153.500 186.958 1.00 61.04  ? 486 THR A CB  1 
ATOM   5483 O OG1 . THR B  1 486 ? 206.822 153.685 187.562 1.00 70.28  ? 486 THR A OG1 1 
ATOM   5484 C CG2 . THR B  1 486 ? 208.313 154.576 185.904 1.00 58.57  ? 486 THR A CG2 1 
ATOM   5485 N N   . PHE B  1 487 ? 210.549 151.592 185.991 1.00 60.30  ? 487 PHE A N   1 
ATOM   5486 C CA  . PHE B  1 487 ? 211.739 151.405 185.167 1.00 62.24  ? 487 PHE A CA  1 
ATOM   5487 C C   . PHE B  1 487 ? 211.478 150.389 184.067 1.00 63.02  ? 487 PHE A C   1 
ATOM   5488 O O   . PHE B  1 487 ? 211.694 150.669 182.885 1.00 58.28  ? 487 PHE A O   1 
ATOM   5489 C CB  . PHE B  1 487 ? 212.931 150.954 186.015 1.00 63.71  ? 487 PHE A CB  1 
ATOM   5490 C CG  . PHE B  1 487 ? 213.256 151.866 187.158 1.00 59.61  ? 487 PHE A CG  1 
ATOM   5491 C CD1 . PHE B  1 487 ? 212.956 153.211 187.101 1.00 61.65  ? 487 PHE A CD1 1 
ATOM   5492 C CD2 . PHE B  1 487 ? 213.901 151.378 188.277 1.00 64.09  ? 487 PHE A CD2 1 
ATOM   5493 C CE1 . PHE B  1 487 ? 213.264 154.045 188.149 1.00 62.56  ? 487 PHE A CE1 1 
ATOM   5494 C CE2 . PHE B  1 487 ? 214.212 152.206 189.329 1.00 61.52  ? 487 PHE A CE2 1 
ATOM   5495 C CZ  . PHE B  1 487 ? 213.894 153.541 189.265 1.00 61.53  ? 487 PHE A CZ  1 
ATOM   5496 N N   . PHE B  1 488 ? 210.991 149.204 184.443 1.00 75.37  ? 488 PHE A N   1 
ATOM   5497 C CA  . PHE B  1 488 ? 210.716 148.164 183.456 1.00 76.87  ? 488 PHE A CA  1 
ATOM   5498 C C   . PHE B  1 488 ? 209.578 148.571 182.530 1.00 77.42  ? 488 PHE A C   1 
ATOM   5499 O O   . PHE B  1 488 ? 209.623 148.295 181.325 1.00 84.74  ? 488 PHE A O   1 
ATOM   5500 C CB  . PHE B  1 488 ? 210.396 146.847 184.161 1.00 78.37  ? 488 PHE A CB  1 
ATOM   5501 C CG  . PHE B  1 488 ? 211.453 146.408 185.133 1.00 77.83  ? 488 PHE A CG  1 
ATOM   5502 C CD1 . PHE B  1 488 ? 212.795 146.571 184.835 1.00 76.15  ? 488 PHE A CD1 1 
ATOM   5503 C CD2 . PHE B  1 488 ? 211.107 145.830 186.342 1.00 79.57  ? 488 PHE A CD2 1 
ATOM   5504 C CE1 . PHE B  1 488 ? 213.770 146.170 185.725 1.00 78.11  ? 488 PHE A CE1 1 
ATOM   5505 C CE2 . PHE B  1 488 ? 212.078 145.426 187.236 1.00 78.79  ? 488 PHE A CE2 1 
ATOM   5506 C CZ  . PHE B  1 488 ? 213.411 145.597 186.928 1.00 79.24  ? 488 PHE A CZ  1 
ATOM   5507 N N   . MET B  1 489 ? 208.546 149.216 183.078 1.00 74.02  ? 489 MET A N   1 
ATOM   5508 C CA  . MET B  1 489 ? 207.471 149.769 182.260 1.00 76.35  ? 489 MET A CA  1 
ATOM   5509 C C   . MET B  1 489 ? 208.016 150.594 181.098 1.00 82.18  ? 489 MET A C   1 
ATOM   5510 O O   . MET B  1 489 ? 207.791 150.267 179.924 1.00 83.45  ? 489 MET A O   1 
ATOM   5511 C CB  . MET B  1 489 ? 206.565 150.622 183.144 1.00 80.17  ? 489 MET A CB  1 
ATOM   5512 C CG  . MET B  1 489 ? 205.306 151.111 182.484 1.00 82.46  ? 489 MET A CG  1 
ATOM   5513 S SD  . MET B  1 489 ? 204.012 149.891 182.241 1.00 93.75  ? 489 MET A SD  1 
ATOM   5514 C CE  . MET B  1 489 ? 202.590 150.979 182.232 1.00 82.57  ? 489 MET A CE  1 
ATOM   5515 N N   . VAL B  1 490 ? 208.743 151.667 181.413 1.00 79.69  ? 490 VAL A N   1 
ATOM   5516 C CA  . VAL B  1 490 ? 209.243 152.568 180.379 1.00 73.43  ? 490 VAL A CA  1 
ATOM   5517 C C   . VAL B  1 490 ? 210.278 151.872 179.505 1.00 77.74  ? 490 VAL A C   1 
ATOM   5518 O O   . VAL B  1 490 ? 210.346 152.116 178.293 1.00 80.29  ? 490 VAL A O   1 
ATOM   5519 C CB  . VAL B  1 490 ? 209.805 153.851 181.015 1.00 72.44  ? 490 VAL A CB  1 
ATOM   5520 C CG1 . VAL B  1 490 ? 210.127 154.878 179.943 1.00 74.36  ? 490 VAL A CG1 1 
ATOM   5521 C CG2 . VAL B  1 490 ? 208.804 154.420 182.002 1.00 71.19  ? 490 VAL A CG2 1 
ATOM   5522 N N   . THR B  1 491 ? 211.061 150.972 180.090 1.00 78.48  ? 491 THR A N   1 
ATOM   5523 C CA  . THR B  1 491 ? 212.062 150.253 179.316 1.00 80.38  ? 491 THR A CA  1 
ATOM   5524 C C   . THR B  1 491 ? 211.395 149.507 178.207 1.00 81.48  ? 491 THR A C   1 
ATOM   5525 O O   . THR B  1 491 ? 211.700 149.720 177.042 1.00 84.85  ? 491 THR A O   1 
ATOM   5526 C CB  . THR B  1 491 ? 212.800 149.192 180.149 1.00 82.31  ? 491 THR A CB  1 
ATOM   5527 O OG1 . THR B  1 491 ? 213.385 149.787 181.307 1.00 83.33  ? 491 THR A OG1 1 
ATOM   5528 C CG2 . THR B  1 491 ? 213.913 148.561 179.347 1.00 84.09  ? 491 THR A CG2 1 
ATOM   5529 N N   . PHE B  1 492 ? 210.445 148.661 178.556 1.00 85.55  ? 492 PHE A N   1 
ATOM   5530 C CA  . PHE B  1 492 ? 209.824 147.801 177.562 1.00 89.44  ? 492 PHE A CA  1 
ATOM   5531 C C   . PHE B  1 492 ? 208.942 148.600 176.616 1.00 90.16  ? 492 PHE A C   1 
ATOM   5532 O O   . PHE B  1 492 ? 208.812 148.234 175.444 1.00 94.68  ? 492 PHE A O   1 
ATOM   5533 C CB  . PHE B  1 492 ? 209.055 146.690 178.270 1.00 88.27  ? 492 PHE A CB  1 
ATOM   5534 C CG  . PHE B  1 492 ? 209.946 145.779 179.063 1.00 88.85  ? 492 PHE A CG  1 
ATOM   5535 C CD1 . PHE B  1 492 ? 211.154 145.353 178.540 1.00 88.75  ? 492 PHE A CD1 1 
ATOM   5536 C CD2 . PHE B  1 492 ? 209.610 145.401 180.349 1.00 91.79  ? 492 PHE A CD2 1 
ATOM   5537 C CE1 . PHE B  1 492 ? 211.991 144.536 179.268 1.00 90.38  ? 492 PHE A CE1 1 
ATOM   5538 C CE2 . PHE B  1 492 ? 210.449 144.590 181.086 1.00 89.05  ? 492 PHE A CE2 1 
ATOM   5539 C CZ  . PHE B  1 492 ? 211.638 144.153 180.543 1.00 90.87  ? 492 PHE A CZ  1 
ATOM   5540 N N   . ALA B  1 493 ? 208.376 149.719 177.077 1.00 89.86  ? 493 ALA A N   1 
ATOM   5541 C CA  . ALA B  1 493 ? 207.647 150.596 176.165 1.00 91.60  ? 493 ALA A CA  1 
ATOM   5542 C C   . ALA B  1 493 ? 208.568 151.162 175.089 1.00 92.70  ? 493 ALA A C   1 
ATOM   5543 O O   . ALA B  1 493 ? 208.233 151.150 173.898 1.00 93.14  ? 493 ALA A O   1 
ATOM   5544 C CB  . ALA B  1 493 ? 206.980 151.724 176.947 1.00 94.97  ? 493 ALA A CB  1 
ATOM   5545 N N   . ALA B  1 494 ? 209.742 151.655 175.489 1.00 94.02  ? 494 ALA A N   1 
ATOM   5546 C CA  . ALA B  1 494 ? 210.670 152.227 174.519 1.00 94.45  ? 494 ALA A CA  1 
ATOM   5547 C C   . ALA B  1 494 ? 211.249 151.156 173.602 1.00 98.94  ? 494 ALA A C   1 
ATOM   5548 O O   . ALA B  1 494 ? 211.455 151.399 172.404 1.00 102.71 ? 494 ALA A O   1 
ATOM   5549 C CB  . ALA B  1 494 ? 211.785 152.980 175.242 1.00 92.26  ? 494 ALA A CB  1 
ATOM   5550 N N   . LEU B  1 495 ? 211.530 149.967 174.145 1.00 101.54 ? 495 LEU A N   1 
ATOM   5551 C CA  . LEU B  1 495 ? 211.996 148.877 173.294 1.00 100.32 ? 495 LEU A CA  1 
ATOM   5552 C C   . LEU B  1 495 ? 210.931 148.477 172.286 1.00 102.43 ? 495 LEU A C   1 
ATOM   5553 O O   . LEU B  1 495 ? 211.248 148.190 171.128 1.00 103.74 ? 495 LEU A O   1 
ATOM   5554 C CB  . LEU B  1 495 ? 212.428 147.674 174.132 1.00 101.21 ? 495 LEU A CB  1 
ATOM   5555 C CG  . LEU B  1 495 ? 213.544 147.909 175.148 1.00 103.67 ? 495 LEU A CG  1 
ATOM   5556 C CD1 . LEU B  1 495 ? 213.437 146.931 176.305 1.00 102.33 ? 495 LEU A CD1 1 
ATOM   5557 C CD2 . LEU B  1 495 ? 214.901 147.807 174.476 1.00 103.82 ? 495 LEU A CD2 1 
ATOM   5558 N N   . TYR B  1 496 ? 209.660 148.458 172.699 1.00 107.63 ? 496 TYR A N   1 
ATOM   5559 C CA  . TYR B  1 496 ? 208.589 148.203 171.743 1.00 107.02 ? 496 TYR A CA  1 
ATOM   5560 C C   . TYR B  1 496 ? 208.544 149.287 170.677 1.00 107.19 ? 496 TYR A C   1 
ATOM   5561 O O   . TYR B  1 496 ? 208.344 148.992 169.494 1.00 111.15 ? 496 TYR A O   1 
ATOM   5562 C CB  . TYR B  1 496 ? 207.245 148.082 172.470 1.00 108.29 ? 496 TYR A CB  1 
ATOM   5563 C CG  . TYR B  1 496 ? 206.017 148.279 171.595 1.00 108.58 ? 496 TYR A CG  1 
ATOM   5564 C CD1 . TYR B  1 496 ? 205.233 147.199 171.229 1.00 108.24 ? 496 TYR A CD1 1 
ATOM   5565 C CD2 . TYR B  1 496 ? 205.593 149.549 171.210 1.00 108.89 ? 496 TYR A CD2 1 
ATOM   5566 C CE1 . TYR B  1 496 ? 204.109 147.363 170.445 1.00 107.29 ? 496 TYR A CE1 1 
ATOM   5567 C CE2 . TYR B  1 496 ? 204.469 149.722 170.428 1.00 109.32 ? 496 TYR A CE2 1 
ATOM   5568 C CZ  . TYR B  1 496 ? 203.728 148.625 170.053 1.00 109.47 ? 496 TYR A CZ  1 
ATOM   5569 O OH  . TYR B  1 496 ? 202.603 148.788 169.280 1.00 113.81 ? 496 TYR A OH  1 
ATOM   5570 N N   . SER B  1 497 ? 208.708 150.548 171.080 1.00 109.98 ? 497 SER A N   1 
ATOM   5571 C CA  . SER B  1 497 ? 208.709 151.638 170.108 1.00 112.50 ? 497 SER A CA  1 
ATOM   5572 C C   . SER B  1 497 ? 209.783 151.423 169.051 1.00 113.66 ? 497 SER A C   1 
ATOM   5573 O O   . SER B  1 497 ? 209.502 151.447 167.847 1.00 114.11 ? 497 SER A O   1 
ATOM   5574 C CB  . SER B  1 497 ? 208.925 152.974 170.815 1.00 111.01 ? 497 SER A CB  1 
ATOM   5575 O OG  . SER B  1 497 ? 210.305 153.221 171.022 1.00 110.88 ? 497 SER A OG  1 
ATOM   5576 N N   . THR B  1 498 ? 211.022 151.196 169.491 1.00 114.65 ? 498 THR A N   1 
ATOM   5577 C CA  . THR B  1 498 ? 212.118 151.003 168.546 1.00 115.12 ? 498 THR A CA  1 
ATOM   5578 C C   . THR B  1 498 ? 211.905 149.755 167.697 1.00 115.20 ? 498 THR A C   1 
ATOM   5579 O O   . THR B  1 498 ? 212.115 149.779 166.478 1.00 115.32 ? 498 THR A O   1 
ATOM   5580 C CB  . THR B  1 498 ? 213.449 150.918 169.293 1.00 116.25 ? 498 THR A CB  1 
ATOM   5581 O OG1 . THR B  1 498 ? 213.423 149.804 170.194 1.00 113.48 ? 498 THR A OG1 1 
ATOM   5582 C CG2 . THR B  1 498 ? 213.701 152.198 170.078 1.00 113.89 ? 498 THR A CG2 1 
ATOM   5583 N N   . HIS B  1 499 ? 211.467 148.662 168.322 1.00 117.35 ? 499 HIS A N   1 
ATOM   5584 C CA  . HIS B  1 499 ? 211.313 147.386 167.640 1.00 118.39 ? 499 HIS A CA  1 
ATOM   5585 C C   . HIS B  1 499 ? 210.223 147.442 166.577 1.00 119.58 ? 499 HIS A C   1 
ATOM   5586 O O   . HIS B  1 499 ? 210.382 146.855 165.501 1.00 120.58 ? 499 HIS A O   1 
ATOM   5587 C CB  . HIS B  1 499 ? 211.000 146.302 168.674 1.00 117.24 ? 499 HIS A CB  1 
ATOM   5588 C CG  . HIS B  1 499 ? 211.628 144.976 168.382 1.00 117.86 ? 499 HIS A CG  1 
ATOM   5589 N ND1 . HIS B  1 499 ? 212.991 144.776 168.416 1.00 116.90 ? 499 HIS A ND1 1 
ATOM   5590 C CD2 . HIS B  1 499 ? 211.080 143.775 168.085 1.00 118.08 ? 499 HIS A CD2 1 
ATOM   5591 C CE1 . HIS B  1 499 ? 213.257 143.513 168.138 1.00 117.08 ? 499 HIS A CE1 1 
ATOM   5592 N NE2 . HIS B  1 499 ? 212.114 142.883 167.934 1.00 118.33 ? 499 HIS A NE2 1 
ATOM   5593 N N   . LYS B  1 500 ? 209.119 148.137 166.856 1.00 119.96 ? 500 LYS A N   1 
ATOM   5594 C CA  . LYS B  1 500 ? 208.045 148.289 165.886 1.00 119.24 ? 500 LYS A CA  1 
ATOM   5595 C C   . LYS B  1 500 ? 208.362 149.313 164.807 1.00 120.41 ? 500 LYS A C   1 
ATOM   5596 O O   . LYS B  1 500 ? 208.002 149.101 163.643 1.00 120.20 ? 500 LYS A O   1 
ATOM   5597 C CB  . LYS B  1 500 ? 206.743 148.682 166.590 1.00 117.51 ? 500 LYS A CB  1 
ATOM   5598 C CG  . LYS B  1 500 ? 205.505 148.535 165.717 1.00 118.58 ? 500 LYS A CG  1 
ATOM   5599 C CD  . LYS B  1 500 ? 204.271 148.223 166.546 1.00 119.58 ? 500 LYS A CD  1 
ATOM   5600 C CE  . LYS B  1 500 ? 203.248 147.443 165.738 1.00 119.34 ? 500 LYS A CE  1 
ATOM   5601 N NZ  . LYS B  1 500 ? 202.061 147.074 166.555 1.00 119.15 ? 500 LYS A NZ  1 
ATOM   5602 N N   . GLU B  1 501 ? 209.029 150.416 165.151 1.00 128.71 ? 501 GLU A N   1 
ATOM   5603 C CA  . GLU B  1 501 ? 209.369 151.414 164.145 1.00 128.13 ? 501 GLU A CA  1 
ATOM   5604 C C   . GLU B  1 501 ? 210.556 151.005 163.286 1.00 129.70 ? 501 GLU A C   1 
ATOM   5605 O O   . GLU B  1 501 ? 210.793 151.633 162.249 1.00 129.66 ? 501 GLU A O   1 
ATOM   5606 C CB  . GLU B  1 501 ? 209.648 152.763 164.813 1.00 127.73 ? 501 GLU A CB  1 
ATOM   5607 C CG  . GLU B  1 501 ? 208.448 153.357 165.535 1.00 129.00 ? 501 GLU A CG  1 
ATOM   5608 C CD  . GLU B  1 501 ? 208.733 154.728 166.114 1.00 130.88 ? 501 GLU A CD  1 
ATOM   5609 O OE1 . GLU B  1 501 ? 209.864 155.227 165.935 1.00 129.91 ? 501 GLU A OE1 1 
ATOM   5610 O OE2 . GLU B  1 501 ? 207.827 155.306 166.751 1.00 132.46 ? 501 GLU A OE2 1 
ATOM   5611 N N   . ARG B  1 502 ? 211.303 149.976 163.684 1.00 134.57 ? 502 ARG A N   1 
ATOM   5612 C CA  . ARG B  1 502 ? 212.383 149.444 162.867 1.00 134.16 ? 502 ARG A CA  1 
ATOM   5613 C C   . ARG B  1 502 ? 212.001 148.159 162.146 1.00 133.11 ? 502 ARG A C   1 
ATOM   5614 O O   . ARG B  1 502 ? 212.815 147.628 161.382 1.00 131.82 ? 502 ARG A O   1 
ATOM   5615 C CB  . ARG B  1 502 ? 213.631 149.215 163.727 1.00 131.81 ? 502 ARG A CB  1 
ATOM   5616 C CG  . ARG B  1 502 ? 214.300 150.504 164.175 1.00 133.74 ? 502 ARG A CG  1 
ATOM   5617 C CD  . ARG B  1 502 ? 215.299 150.267 165.293 1.00 134.32 ? 502 ARG A CD  1 
ATOM   5618 N NE  . ARG B  1 502 ? 215.696 151.517 165.930 1.00 135.49 ? 502 ARG A NE  1 
ATOM   5619 C CZ  . ARG B  1 502 ? 216.490 151.601 166.988 1.00 135.31 ? 502 ARG A CZ  1 
ATOM   5620 N NH1 . ARG B  1 502 ? 216.996 150.521 167.561 1.00 133.94 ? 502 ARG A NH1 1 
ATOM   5621 N NH2 . ARG B  1 502 ? 216.784 152.799 167.486 1.00 132.74 ? 502 ARG A NH2 1 
ATOM   5622 N N   . GLY B  1 503 ? 210.790 147.649 162.362 1.00 133.28 ? 503 GLY A N   1 
ATOM   5623 C CA  . GLY B  1 503 ? 210.305 146.495 161.631 1.00 131.60 ? 503 GLY A CA  1 
ATOM   5624 C C   . GLY B  1 503 ? 211.020 145.199 161.953 1.00 132.42 ? 503 GLY A C   1 
ATOM   5625 O O   . GLY B  1 503 ? 211.715 144.641 161.099 1.00 133.25 ? 503 GLY A O   1 
ATOM   5626 N N   . HIS B  1 504 ? 210.858 144.709 163.177 1.00 129.17 ? 504 HIS A N   1 
ATOM   5627 C CA  . HIS B  1 504 ? 211.476 143.466 163.611 1.00 129.62 ? 504 HIS A CA  1 
ATOM   5628 C C   . HIS B  1 504 ? 210.405 142.411 163.860 1.00 127.62 ? 504 HIS A C   1 
ATOM   5629 O O   . HIS B  1 504 ? 209.203 142.689 163.832 1.00 127.51 ? 504 HIS A O   1 
ATOM   5630 C CB  . HIS B  1 504 ? 212.322 143.675 164.873 1.00 130.71 ? 504 HIS A CB  1 
ATOM   5631 C CG  . HIS B  1 504 ? 213.468 144.622 164.693 1.00 131.50 ? 504 HIS A CG  1 
ATOM   5632 N ND1 . HIS B  1 504 ? 214.595 144.581 165.486 1.00 130.33 ? 504 HIS A ND1 1 
ATOM   5633 C CD2 . HIS B  1 504 ? 213.665 145.634 163.815 1.00 130.21 ? 504 HIS A CD2 1 
ATOM   5634 C CE1 . HIS B  1 504 ? 215.435 145.526 165.105 1.00 130.54 ? 504 HIS A CE1 1 
ATOM   5635 N NE2 . HIS B  1 504 ? 214.895 146.179 164.092 1.00 129.39 ? 504 HIS A NE2 1 
ATOM   5636 N N   . SER B  1 505 ? 210.860 141.183 164.108 1.00 126.67 ? 505 SER A N   1 
ATOM   5637 C CA  . SER B  1 505 ? 209.969 140.039 164.253 1.00 129.35 ? 505 SER A CA  1 
ATOM   5638 C C   . SER B  1 505 ? 209.557 139.760 165.693 1.00 129.65 ? 505 SER A C   1 
ATOM   5639 O O   . SER B  1 505 ? 208.705 138.894 165.916 1.00 130.15 ? 505 SER A O   1 
ATOM   5640 C CB  . SER B  1 505 ? 210.628 138.785 163.667 1.00 127.97 ? 505 SER A CB  1 
ATOM   5641 O OG  . SER B  1 505 ? 211.830 138.475 164.349 1.00 126.15 ? 505 SER A OG  1 
ATOM   5642 N N   . ASP B  1 506 ? 210.132 140.460 166.672 1.00 124.88 ? 506 ASP A N   1 
ATOM   5643 C CA  . ASP B  1 506 ? 209.787 140.261 168.074 1.00 124.73 ? 506 ASP A CA  1 
ATOM   5644 C C   . ASP B  1 506 ? 209.007 141.438 168.649 1.00 124.49 ? 506 ASP A C   1 
ATOM   5645 O O   . ASP B  1 506 ? 208.975 141.623 169.871 1.00 123.66 ? 506 ASP A O   1 
ATOM   5646 C CB  . ASP B  1 506 ? 211.047 140.000 168.900 1.00 124.63 ? 506 ASP A CB  1 
ATOM   5647 C CG  . ASP B  1 506 ? 211.734 138.704 168.522 1.00 125.50 ? 506 ASP A CG  1 
ATOM   5648 O OD1 . ASP B  1 506 ? 211.203 137.981 167.652 1.00 125.27 ? 506 ASP A OD1 1 
ATOM   5649 O OD2 . ASP B  1 506 ? 212.804 138.407 169.093 1.00 125.85 ? 506 ASP A OD2 1 
ATOM   5650 N N   . THR B  1 507 ? 208.389 142.248 167.786 1.00 119.29 ? 507 THR A N   1 
ATOM   5651 C CA  . THR B  1 507 ? 207.597 143.376 168.264 1.00 117.88 ? 507 THR A CA  1 
ATOM   5652 C C   . THR B  1 507 ? 206.408 142.900 169.087 1.00 118.46 ? 507 THR A C   1 
ATOM   5653 O O   . THR B  1 507 ? 206.090 143.486 170.128 1.00 120.45 ? 507 THR A O   1 
ATOM   5654 C CB  . THR B  1 507 ? 207.134 144.229 167.081 1.00 118.44 ? 507 THR A CB  1 
ATOM   5655 O OG1 . THR B  1 507 ? 208.228 145.022 166.605 1.00 118.45 ? 507 THR A OG1 1 
ATOM   5656 C CG2 . THR B  1 507 ? 205.993 145.148 167.489 1.00 116.65 ? 507 THR A CG2 1 
ATOM   5657 N N   . MET B  1 508 ? 205.741 141.833 168.640 1.00 118.62 ? 508 MET A N   1 
ATOM   5658 C CA  . MET B  1 508 ? 204.630 141.283 169.409 1.00 117.28 ? 508 MET A CA  1 
ATOM   5659 C C   . MET B  1 508 ? 205.101 140.754 170.758 1.00 116.52 ? 508 MET A C   1 
ATOM   5660 O O   . MET B  1 508 ? 204.416 140.926 171.772 1.00 116.96 ? 508 MET A O   1 
ATOM   5661 C CB  . MET B  1 508 ? 203.930 140.181 168.615 1.00 117.69 ? 508 MET A CB  1 
ATOM   5662 C CG  . MET B  1 508 ? 203.309 140.652 167.310 1.00 120.05 ? 508 MET A CG  1 
ATOM   5663 S SD  . MET B  1 508 ? 203.395 139.406 166.010 1.00 122.11 ? 508 MET A SD  1 
ATOM   5664 C CE  . MET B  1 508 ? 204.729 140.055 165.009 1.00 116.70 ? 508 MET A CE  1 
ATOM   5665 N N   . VAL B  1 509 ? 206.266 140.103 170.789 1.00 117.72 ? 509 VAL A N   1 
ATOM   5666 C CA  . VAL B  1 509 ? 206.802 139.600 172.052 1.00 119.86 ? 509 VAL A CA  1 
ATOM   5667 C C   . VAL B  1 509 ? 207.096 140.752 173.002 1.00 118.02 ? 509 VAL A C   1 
ATOM   5668 O O   . VAL B  1 509 ? 206.781 140.688 174.198 1.00 116.40 ? 509 VAL A O   1 
ATOM   5669 C CB  . VAL B  1 509 ? 208.055 138.743 171.800 1.00 121.35 ? 509 VAL A CB  1 
ATOM   5670 C CG1 . VAL B  1 509 ? 208.310 137.821 172.982 1.00 119.45 ? 509 VAL A CG1 1 
ATOM   5671 C CG2 . VAL B  1 509 ? 207.901 137.943 170.516 1.00 119.70 ? 509 VAL A CG2 1 
ATOM   5672 N N   . PHE B  1 510 ? 207.709 141.820 172.488 1.00 109.89 ? 510 PHE A N   1 
ATOM   5673 C CA  . PHE B  1 510 ? 207.988 142.982 173.325 1.00 109.13 ? 510 PHE A CA  1 
ATOM   5674 C C   . PHE B  1 510 ? 206.701 143.620 173.830 1.00 108.16 ? 510 PHE A C   1 
ATOM   5675 O O   . PHE B  1 510 ? 206.617 144.021 174.995 1.00 109.97 ? 510 PHE A O   1 
ATOM   5676 C CB  . PHE B  1 510 ? 208.830 143.998 172.556 1.00 110.06 ? 510 PHE A CB  1 
ATOM   5677 C CG  . PHE B  1 510 ? 210.304 143.869 172.803 1.00 110.27 ? 510 PHE A CG  1 
ATOM   5678 C CD1 . PHE B  1 510 ? 210.798 143.813 174.094 1.00 107.29 ? 510 PHE A CD1 1 
ATOM   5679 C CD2 . PHE B  1 510 ? 211.194 143.796 171.746 1.00 111.82 ? 510 PHE A CD2 1 
ATOM   5680 C CE1 . PHE B  1 510 ? 212.151 143.693 174.328 1.00 108.38 ? 510 PHE A CE1 1 
ATOM   5681 C CE2 . PHE B  1 510 ? 212.550 143.675 171.973 1.00 109.02 ? 510 PHE A CE2 1 
ATOM   5682 C CZ  . PHE B  1 510 ? 213.029 143.623 173.266 1.00 108.34 ? 510 PHE A CZ  1 
ATOM   5683 N N   . PHE B  1 511 ? 205.686 143.720 172.970 1.00 106.71 ? 511 PHE A N   1 
ATOM   5684 C CA  . PHE B  1 511 ? 204.414 144.298 173.391 1.00 106.19 ? 511 PHE A CA  1 
ATOM   5685 C C   . PHE B  1 511 ? 203.769 143.457 174.483 1.00 107.63 ? 511 PHE A C   1 
ATOM   5686 O O   . PHE B  1 511 ? 203.242 143.992 175.464 1.00 110.03 ? 511 PHE A O   1 
ATOM   5687 C CB  . PHE B  1 511 ? 203.473 144.440 172.193 1.00 109.17 ? 511 PHE A CB  1 
ATOM   5688 C CG  . PHE B  1 511 ? 202.084 144.895 172.559 1.00 109.21 ? 511 PHE A CG  1 
ATOM   5689 C CD1 . PHE B  1 511 ? 201.098 143.981 172.896 1.00 108.08 ? 511 PHE A CD1 1 
ATOM   5690 C CD2 . PHE B  1 511 ? 201.773 146.244 172.583 1.00 108.06 ? 511 PHE A CD2 1 
ATOM   5691 C CE1 . PHE B  1 511 ? 199.830 144.406 173.237 1.00 107.25 ? 511 PHE A CE1 1 
ATOM   5692 C CE2 . PHE B  1 511 ? 200.507 146.672 172.922 1.00 108.39 ? 511 PHE A CE2 1 
ATOM   5693 C CZ  . PHE B  1 511 ? 199.536 145.753 173.250 1.00 107.96 ? 511 PHE A CZ  1 
ATOM   5694 N N   . TYR B  1 512 ? 203.786 142.133 174.322 1.00 112.76 ? 512 TYR A N   1 
ATOM   5695 C CA  . TYR B  1 512 ? 203.187 141.264 175.328 1.00 114.15 ? 512 TYR A CA  1 
ATOM   5696 C C   . TYR B  1 512 ? 203.939 141.348 176.649 1.00 112.51 ? 512 TYR A C   1 
ATOM   5697 O O   . TYR B  1 512 ? 203.323 141.394 177.718 1.00 109.43 ? 512 TYR A O   1 
ATOM   5698 C CB  . TYR B  1 512 ? 203.136 139.823 174.823 1.00 115.64 ? 512 TYR A CB  1 
ATOM   5699 C CG  . TYR B  1 512 ? 202.253 139.640 173.610 1.00 116.85 ? 512 TYR A CG  1 
ATOM   5700 C CD1 . TYR B  1 512 ? 201.132 140.437 173.421 1.00 114.02 ? 512 TYR A CD1 1 
ATOM   5701 C CD2 . TYR B  1 512 ? 202.528 138.661 172.664 1.00 116.78 ? 512 TYR A CD2 1 
ATOM   5702 C CE1 . TYR B  1 512 ? 200.317 140.275 172.319 1.00 115.32 ? 512 TYR A CE1 1 
ATOM   5703 C CE2 . TYR B  1 512 ? 201.719 138.491 171.557 1.00 116.65 ? 512 TYR A CE2 1 
ATOM   5704 C CZ  . TYR B  1 512 ? 200.614 139.300 171.391 1.00 117.16 ? 512 TYR A CZ  1 
ATOM   5705 O OH  . TYR B  1 512 ? 199.804 139.133 170.291 1.00 115.13 ? 512 TYR A OH  1 
ATOM   5706 N N   . LEU B  1 513 ? 205.272 141.385 176.598 1.00 104.58 ? 513 LEU A N   1 
ATOM   5707 C CA  . LEU B  1 513 ? 206.054 141.485 177.827 1.00 103.39 ? 513 LEU A CA  1 
ATOM   5708 C C   . LEU B  1 513 ? 205.837 142.831 178.512 1.00 103.41 ? 513 LEU A C   1 
ATOM   5709 O O   . LEU B  1 513 ? 205.783 142.911 179.746 1.00 103.51 ? 513 LEU A O   1 
ATOM   5710 C CB  . LEU B  1 513 ? 207.531 141.257 177.509 1.00 103.26 ? 513 LEU A CB  1 
ATOM   5711 C CG  . LEU B  1 513 ? 208.445 140.842 178.658 1.00 101.34 ? 513 LEU A CG  1 
ATOM   5712 C CD1 . LEU B  1 513 ? 209.463 139.817 178.188 1.00 102.29 ? 513 LEU A CD1 1 
ATOM   5713 C CD2 . LEU B  1 513 ? 209.143 142.056 179.214 1.00 102.21 ? 513 LEU A CD2 1 
ATOM   5714 N N   . TRP B  1 514 ? 205.711 143.900 177.725 1.00 97.20  ? 514 TRP A N   1 
ATOM   5715 C CA  . TRP B  1 514 ? 205.389 145.212 178.275 1.00 92.34  ? 514 TRP A CA  1 
ATOM   5716 C C   . TRP B  1 514 ? 204.003 145.252 178.908 1.00 90.91  ? 514 TRP A C   1 
ATOM   5717 O O   . TRP B  1 514 ? 203.821 145.841 179.977 1.00 94.58  ? 514 TRP A O   1 
ATOM   5718 C CB  . TRP B  1 514 ? 205.526 146.272 177.187 1.00 94.29  ? 514 TRP A CB  1 
ATOM   5719 C CG  . TRP B  1 514 ? 204.975 147.573 177.601 1.00 94.18  ? 514 TRP A CG  1 
ATOM   5720 C CD1 . TRP B  1 514 ? 205.610 148.565 178.273 1.00 96.10  ? 514 TRP A CD1 1 
ATOM   5721 C CD2 . TRP B  1 514 ? 203.658 148.054 177.317 1.00 95.24  ? 514 TRP A CD2 1 
ATOM   5722 N NE1 . TRP B  1 514 ? 204.759 149.625 178.458 1.00 96.53  ? 514 TRP A NE1 1 
ATOM   5723 C CE2 . TRP B  1 514 ? 203.554 149.336 177.872 1.00 93.14  ? 514 TRP A CE2 1 
ATOM   5724 C CE3 . TRP B  1 514 ? 202.553 147.516 176.653 1.00 95.78  ? 514 TRP A CE3 1 
ATOM   5725 C CZ2 . TRP B  1 514 ? 202.388 150.085 177.789 1.00 93.13  ? 514 TRP A CZ2 1 
ATOM   5726 C CZ3 . TRP B  1 514 ? 201.403 148.268 176.565 1.00 95.04  ? 514 TRP A CZ3 1 
ATOM   5727 C CH2 . TRP B  1 514 ? 201.327 149.538 177.129 1.00 94.73  ? 514 TRP A CH2 1 
ATOM   5728 N N   . ILE B  1 515 ? 203.007 144.653 178.251 1.00 92.00  ? 515 ILE A N   1 
ATOM   5729 C CA  . ILE B  1 515 ? 201.694 144.516 178.873 1.00 94.19  ? 515 ILE A CA  1 
ATOM   5730 C C   . ILE B  1 515 ? 201.808 143.723 180.163 1.00 96.57  ? 515 ILE A C   1 
ATOM   5731 O O   . ILE B  1 515 ? 201.147 144.038 181.158 1.00 95.21  ? 515 ILE A O   1 
ATOM   5732 C CB  . ILE B  1 515 ? 200.698 143.853 177.902 1.00 98.02  ? 515 ILE A CB  1 
ATOM   5733 C CG1 . ILE B  1 515 ? 200.235 144.845 176.841 1.00 96.38  ? 515 ILE A CG1 1 
ATOM   5734 C CG2 . ILE B  1 515 ? 199.483 143.311 178.655 1.00 97.02  ? 515 ILE A CG2 1 
ATOM   5735 C CD1 . ILE B  1 515 ? 199.216 145.825 177.358 1.00 92.30  ? 515 ILE A CD1 1 
ATOM   5736 N N   . VAL B  1 516 ? 202.656 142.696 180.171 1.00 93.71  ? 516 VAL A N   1 
ATOM   5737 C CA  . VAL B  1 516 ? 202.828 141.874 181.361 1.00 93.57  ? 516 VAL A CA  1 
ATOM   5738 C C   . VAL B  1 516 ? 203.384 142.702 182.511 1.00 92.03  ? 516 VAL A C   1 
ATOM   5739 O O   . VAL B  1 516 ? 202.907 142.600 183.643 1.00 88.71  ? 516 VAL A O   1 
ATOM   5740 C CB  . VAL B  1 516 ? 203.721 140.664 181.036 1.00 96.72  ? 516 VAL A CB  1 
ATOM   5741 C CG1 . VAL B  1 516 ? 204.376 140.116 182.294 1.00 94.30  ? 516 VAL A CG1 1 
ATOM   5742 C CG2 . VAL B  1 516 ? 202.904 139.588 180.346 1.00 97.04  ? 516 VAL A CG2 1 
ATOM   5743 N N   . PHE B  1 517 ? 204.389 143.540 182.246 1.00 91.62  ? 517 PHE A N   1 
ATOM   5744 C CA  . PHE B  1 517 ? 204.949 144.370 183.316 1.00 90.63  ? 517 PHE A CA  1 
ATOM   5745 C C   . PHE B  1 517 ? 203.981 145.477 183.731 1.00 87.18  ? 517 PHE A C   1 
ATOM   5746 O O   . PHE B  1 517 ? 203.897 145.828 184.918 1.00 86.83  ? 517 PHE A O   1 
ATOM   5747 C CB  . PHE B  1 517 ? 206.300 144.940 182.895 1.00 84.38  ? 517 PHE A CB  1 
ATOM   5748 C CG  . PHE B  1 517 ? 207.451 144.038 183.227 1.00 83.45  ? 517 PHE A CG  1 
ATOM   5749 C CD1 . PHE B  1 517 ? 207.786 142.983 182.397 1.00 87.53  ? 517 PHE A CD1 1 
ATOM   5750 C CD2 . PHE B  1 517 ? 208.171 144.219 184.393 1.00 85.16  ? 517 PHE A CD2 1 
ATOM   5751 C CE1 . PHE B  1 517 ? 208.838 142.145 182.709 1.00 90.62  ? 517 PHE A CE1 1 
ATOM   5752 C CE2 . PHE B  1 517 ? 209.223 143.385 184.710 1.00 90.67  ? 517 PHE A CE2 1 
ATOM   5753 C CZ  . PHE B  1 517 ? 209.557 142.347 183.867 1.00 91.88  ? 517 PHE A CZ  1 
ATOM   5754 N N   . TYR B  1 518 ? 203.242 146.033 182.775 1.00 82.81  ? 518 TYR A N   1 
ATOM   5755 C CA  . TYR B  1 518 ? 202.001 146.717 183.087 1.00 80.24  ? 518 TYR A CA  1 
ATOM   5756 C C   . TYR B  1 518 ? 201.078 145.749 183.826 1.00 81.99  ? 518 TYR A C   1 
ATOM   5757 O O   . TYR B  1 518 ? 201.337 144.552 183.913 1.00 78.91  ? 518 TYR A O   1 
ATOM   5758 C CB  . TYR B  1 518 ? 201.350 147.234 181.803 1.00 80.97  ? 518 TYR A CB  1 
ATOM   5759 C CG  . TYR B  1 518 ? 200.225 148.229 181.991 1.00 77.74  ? 518 TYR A CG  1 
ATOM   5760 C CD1 . TYR B  1 518 ? 200.087 148.947 183.168 1.00 78.79  ? 518 TYR A CD1 1 
ATOM   5761 C CD2 . TYR B  1 518 ? 199.287 148.432 180.988 1.00 82.13  ? 518 TYR A CD2 1 
ATOM   5762 C CE1 . TYR B  1 518 ? 199.054 149.837 183.338 1.00 85.65  ? 518 TYR A CE1 1 
ATOM   5763 C CE2 . TYR B  1 518 ? 198.249 149.326 181.150 1.00 78.66  ? 518 TYR A CE2 1 
ATOM   5764 C CZ  . TYR B  1 518 ? 198.139 150.028 182.329 1.00 80.68  ? 518 TYR A CZ  1 
ATOM   5765 O OH  . TYR B  1 518 ? 197.113 150.925 182.512 1.00 81.72  ? 518 TYR A OH  1 
ATOM   5766 N N   . ILE B  1 519 ? 199.992 146.284 184.376 1.00 82.21  ? 519 ILE A N   1 
ATOM   5767 C CA  . ILE B  1 519 ? 199.077 145.533 185.229 1.00 79.91  ? 519 ILE A CA  1 
ATOM   5768 C C   . ILE B  1 519 ? 199.766 145.228 186.554 1.00 80.66  ? 519 ILE A C   1 
ATOM   5769 O O   . ILE B  1 519 ? 199.237 145.586 187.607 1.00 78.14  ? 519 ILE A O   1 
ATOM   5770 C CB  . ILE B  1 519 ? 198.550 144.255 184.547 1.00 78.95  ? 519 ILE A CB  1 
ATOM   5771 C CG1 . ILE B  1 519 ? 198.013 144.584 183.152 1.00 78.14  ? 519 ILE A CG1 1 
ATOM   5772 C CG2 . ILE B  1 519 ? 197.475 143.600 185.398 1.00 79.36  ? 519 ILE A CG2 1 
ATOM   5773 C CD1 . ILE B  1 519 ? 197.688 143.370 182.321 1.00 78.50  ? 519 ILE A CD1 1 
ATOM   5774 N N   . ILE B  1 520 ? 200.954 144.604 186.541 1.00 80.26  ? 520 ILE A N   1 
ATOM   5775 C CA  . ILE B  1 520 ? 201.684 144.499 187.807 1.00 77.77  ? 520 ILE A CA  1 
ATOM   5776 C C   . ILE B  1 520 ? 202.080 145.875 188.318 1.00 75.13  ? 520 ILE A C   1 
ATOM   5777 O O   . ILE B  1 520 ? 201.932 146.165 189.508 1.00 72.83  ? 520 ILE A O   1 
ATOM   5778 C CB  . ILE B  1 520 ? 202.913 143.565 187.741 1.00 76.33  ? 520 ILE A CB  1 
ATOM   5779 C CG1 . ILE B  1 520 ? 202.669 142.264 186.984 1.00 77.59  ? 520 ILE A CG1 1 
ATOM   5780 C CG2 . ILE B  1 520 ? 203.444 143.281 189.131 1.00 75.68  ? 520 ILE A CG2 1 
ATOM   5781 C CD1 . ILE B  1 520 ? 203.881 141.822 186.214 1.00 75.47  ? 520 ILE A CD1 1 
ATOM   5782 N N   . SER B  1 521 ? 202.591 146.745 187.444 1.00 72.29  ? 521 SER A N   1 
ATOM   5783 C CA  . SER B  1 521 ? 202.959 148.082 187.907 1.00 70.05  ? 521 SER A CA  1 
ATOM   5784 C C   . SER B  1 521 ? 201.751 148.821 188.484 1.00 68.85  ? 521 SER A C   1 
ATOM   5785 O O   . SER B  1 521 ? 201.807 149.364 189.598 1.00 70.78  ? 521 SER A O   1 
ATOM   5786 C CB  . SER B  1 521 ? 203.586 148.875 186.764 1.00 65.70  ? 521 SER A CB  1 
ATOM   5787 O OG  . SER B  1 521 ? 203.656 150.249 187.088 1.00 60.91  ? 521 SER A OG  1 
ATOM   5788 N N   . SER B  1 522 ? 200.637 148.824 187.747 1.00 62.25  ? 522 SER A N   1 
ATOM   5789 C CA  . SER B  1 522 ? 199.449 149.545 188.193 1.00 56.18  ? 522 SER A CA  1 
ATOM   5790 C C   . SER B  1 522 ? 198.858 148.939 189.459 1.00 64.14  ? 522 SER A C   1 
ATOM   5791 O O   . SER B  1 522 ? 198.446 149.673 190.359 1.00 69.22  ? 522 SER A O   1 
ATOM   5792 C CB  . SER B  1 522 ? 198.408 149.584 187.079 1.00 55.37  ? 522 SER A CB  1 
ATOM   5793 O OG  . SER B  1 522 ? 198.679 150.650 186.190 1.00 66.62  ? 522 SER A OG  1 
ATOM   5794 N N   . CYS B  1 523 ? 198.805 147.608 189.555 1.00 67.56  ? 523 CYS A N   1 
ATOM   5795 C CA  . CYS B  1 523 ? 198.237 146.980 190.742 1.00 69.71  ? 523 CYS A CA  1 
ATOM   5796 C C   . CYS B  1 523 ? 199.141 147.169 191.950 1.00 63.86  ? 523 CYS A C   1 
ATOM   5797 O O   . CYS B  1 523 ? 198.656 147.371 193.065 1.00 54.40  ? 523 CYS A O   1 
ATOM   5798 C CB  . CYS B  1 523 ? 197.986 145.497 190.478 1.00 68.62  ? 523 CYS A CB  1 
ATOM   5799 S SG  . CYS B  1 523 ? 196.320 145.114 189.890 1.00 72.65  ? 523 CYS A SG  1 
ATOM   5800 N N   . TYR B  1 524 ? 200.458 147.112 191.748 1.00 62.43  ? 524 TYR A N   1 
ATOM   5801 C CA  . TYR B  1 524 ? 201.402 147.409 192.816 1.00 61.73  ? 524 TYR A CA  1 
ATOM   5802 C C   . TYR B  1 524 ? 201.156 148.803 193.372 1.00 62.78  ? 524 TYR A C   1 
ATOM   5803 O O   . TYR B  1 524 ? 200.945 148.979 194.581 1.00 71.20  ? 524 TYR A O   1 
ATOM   5804 C CB  . TYR B  1 524 ? 202.822 147.284 192.261 1.00 59.49  ? 524 TYR A CB  1 
ATOM   5805 C CG  . TYR B  1 524 ? 203.913 146.980 193.258 1.00 58.50  ? 524 TYR A CG  1 
ATOM   5806 C CD1 . TYR B  1 524 ? 203.758 147.250 194.608 1.00 59.78  ? 524 TYR A CD1 1 
ATOM   5807 C CD2 . TYR B  1 524 ? 205.110 146.420 192.837 1.00 54.79  ? 524 TYR A CD2 1 
ATOM   5808 C CE1 . TYR B  1 524 ? 204.766 146.969 195.508 1.00 63.35  ? 524 TYR A CE1 1 
ATOM   5809 C CE2 . TYR B  1 524 ? 206.117 146.137 193.724 1.00 54.82  ? 524 TYR A CE2 1 
ATOM   5810 C CZ  . TYR B  1 524 ? 205.943 146.412 195.057 1.00 63.06  ? 524 TYR A CZ  1 
ATOM   5811 O OH  . TYR B  1 524 ? 206.957 146.128 195.938 1.00 66.74  ? 524 TYR A OH  1 
ATOM   5812 N N   . THR B  1 525 ? 201.126 149.803 192.487 1.00 58.19  ? 525 THR A N   1 
ATOM   5813 C CA  . THR B  1 525 ? 200.914 151.175 192.934 1.00 51.14  ? 525 THR A CA  1 
ATOM   5814 C C   . THR B  1 525 ? 199.533 151.351 193.557 1.00 60.05  ? 525 THR A C   1 
ATOM   5815 O O   . THR B  1 525 ? 199.382 152.065 194.553 1.00 64.41  ? 525 THR A O   1 
ATOM   5816 C CB  . THR B  1 525 ? 201.108 152.138 191.766 1.00 54.59  ? 525 THR A CB  1 
ATOM   5817 O OG1 . THR B  1 525 ? 200.553 151.564 190.578 1.00 66.05  ? 525 THR A OG1 1 
ATOM   5818 C CG2 . THR B  1 525 ? 202.585 152.397 191.540 1.00 56.71  ? 525 THR A CG2 1 
ATOM   5819 N N   . LEU B  1 526 ? 198.516 150.690 192.999 1.00 53.71  ? 526 LEU A N   1 
ATOM   5820 C CA  . LEU B  1 526 ? 197.149 150.860 193.480 1.00 49.13  ? 526 LEU A CA  1 
ATOM   5821 C C   . LEU B  1 526 ? 196.966 150.251 194.864 1.00 59.41  ? 526 LEU A C   1 
ATOM   5822 O O   . LEU B  1 526 ? 196.370 150.873 195.752 1.00 66.09  ? 526 LEU A O   1 
ATOM   5823 C CB  . LEU B  1 526 ? 196.175 150.237 192.482 1.00 43.05  ? 526 LEU A CB  1 
ATOM   5824 C CG  . LEU B  1 526 ? 194.696 150.208 192.861 1.00 47.40  ? 526 LEU A CG  1 
ATOM   5825 C CD1 . LEU B  1 526 ? 194.164 151.617 193.021 1.00 56.75  ? 526 LEU A CD1 1 
ATOM   5826 C CD2 . LEU B  1 526 ? 193.900 149.447 191.817 1.00 50.80  ? 526 LEU A CD2 1 
ATOM   5827 N N   . ILE B  1 527 ? 197.457 149.026 195.065 1.00 56.34  ? 527 ILE A N   1 
ATOM   5828 C CA  . ILE B  1 527 ? 197.364 148.400 196.378 1.00 55.44  ? 527 ILE A CA  1 
ATOM   5829 C C   . ILE B  1 527 ? 198.180 149.182 197.393 1.00 54.57  ? 527 ILE A C   1 
ATOM   5830 O O   . ILE B  1 527 ? 197.765 149.345 198.547 1.00 51.80  ? 527 ILE A O   1 
ATOM   5831 C CB  . ILE B  1 527 ? 197.801 146.926 196.310 1.00 53.52  ? 527 ILE A CB  1 
ATOM   5832 C CG1 . ILE B  1 527 ? 196.943 146.162 195.301 1.00 59.27  ? 527 ILE A CG1 1 
ATOM   5833 C CG2 . ILE B  1 527 ? 197.707 146.281 197.681 1.00 51.06  ? 527 ILE A CG2 1 
ATOM   5834 C CD1 . ILE B  1 527 ? 197.500 144.809 194.928 1.00 59.26  ? 527 ILE A CD1 1 
ATOM   5835 N N   . TRP B  1 528 ? 199.343 149.696 196.982 1.00 58.20  ? 528 TRP A N   1 
ATOM   5836 C CA  . TRP B  1 528 ? 200.110 150.551 197.878 1.00 50.61  ? 528 TRP A CA  1 
ATOM   5837 C C   . TRP B  1 528 ? 199.297 151.769 198.293 1.00 54.82  ? 528 TRP A C   1 
ATOM   5838 O O   . TRP B  1 528 ? 199.179 152.072 199.485 1.00 65.15  ? 528 TRP A O   1 
ATOM   5839 C CB  . TRP B  1 528 ? 201.414 150.972 197.208 1.00 52.08  ? 528 TRP A CB  1 
ATOM   5840 C CG  . TRP B  1 528 ? 202.473 151.362 198.177 1.00 53.00  ? 528 TRP A CG  1 
ATOM   5841 C CD1 . TRP B  1 528 ? 202.875 152.625 198.488 1.00 56.50  ? 528 TRP A CD1 1 
ATOM   5842 C CD2 . TRP B  1 528 ? 203.267 150.480 198.974 1.00 52.80  ? 528 TRP A CD2 1 
ATOM   5843 N NE1 . TRP B  1 528 ? 203.874 152.586 199.428 1.00 58.31  ? 528 TRP A NE1 1 
ATOM   5844 C CE2 . TRP B  1 528 ? 204.132 151.279 199.744 1.00 55.33  ? 528 TRP A CE2 1 
ATOM   5845 C CE3 . TRP B  1 528 ? 203.331 149.092 199.110 1.00 59.03  ? 528 TRP A CE3 1 
ATOM   5846 C CZ2 . TRP B  1 528 ? 205.050 150.736 200.635 1.00 57.89  ? 528 TRP A CZ2 1 
ATOM   5847 C CZ3 . TRP B  1 528 ? 204.240 148.557 199.995 1.00 64.38  ? 528 TRP A CZ3 1 
ATOM   5848 C CH2 . TRP B  1 528 ? 205.089 149.376 200.746 1.00 64.03  ? 528 TRP A CH2 1 
ATOM   5849 N N   . ASP B  1 529 ? 198.686 152.450 197.321 1.00 51.71  ? 529 ASP A N   1 
ATOM   5850 C CA  . ASP B  1 529 ? 197.902 153.643 197.620 1.00 54.04  ? 529 ASP A CA  1 
ATOM   5851 C C   . ASP B  1 529 ? 196.751 153.330 198.565 1.00 59.32  ? 529 ASP A C   1 
ATOM   5852 O O   . ASP B  1 529 ? 196.509 154.069 199.526 1.00 60.82  ? 529 ASP A O   1 
ATOM   5853 C CB  . ASP B  1 529 ? 197.366 154.253 196.325 1.00 52.81  ? 529 ASP A CB  1 
ATOM   5854 C CG  . ASP B  1 529 ? 198.453 154.869 195.477 1.00 56.67  ? 529 ASP A CG  1 
ATOM   5855 O OD1 . ASP B  1 529 ? 199.613 154.919 195.933 1.00 60.67  ? 529 ASP A OD1 1 
ATOM   5856 O OD2 . ASP B  1 529 ? 198.147 155.302 194.347 1.00 46.52  ? 529 ASP A OD2 1 
ATOM   5857 N N   . LEU B  1 530 ? 196.031 152.238 198.314 1.00 56.66  ? 530 LEU A N   1 
ATOM   5858 C CA  . LEU B  1 530 ? 194.841 151.940 199.098 1.00 54.86  ? 530 LEU A CA  1 
ATOM   5859 C C   . LEU B  1 530 ? 195.138 151.281 200.439 1.00 62.59  ? 530 LEU A C   1 
ATOM   5860 O O   . LEU B  1 530 ? 194.251 151.255 201.298 1.00 63.65  ? 530 LEU A O   1 
ATOM   5861 C CB  . LEU B  1 530 ? 193.889 151.049 198.299 1.00 46.95  ? 530 LEU A CB  1 
ATOM   5862 C CG  . LEU B  1 530 ? 193.509 151.554 196.910 1.00 50.18  ? 530 LEU A CG  1 
ATOM   5863 C CD1 . LEU B  1 530 ? 192.686 150.513 196.173 1.00 58.97  ? 530 LEU A CD1 1 
ATOM   5864 C CD2 . LEU B  1 530 ? 192.760 152.867 197.013 1.00 57.04  ? 530 LEU A CD2 1 
ATOM   5865 N N   . LYS B  1 531 ? 196.343 150.754 200.652 1.00 70.68  ? 531 LYS A N   1 
ATOM   5866 C CA  . LYS B  1 531 ? 196.654 150.075 201.903 1.00 67.61  ? 531 LYS A CA  1 
ATOM   5867 C C   . LYS B  1 531 ? 197.608 150.853 202.794 1.00 71.81  ? 531 LYS A C   1 
ATOM   5868 O O   . LYS B  1 531 ? 197.359 150.976 203.996 1.00 74.46  ? 531 LYS A O   1 
ATOM   5869 C CB  . LYS B  1 531 ? 197.233 148.684 201.617 1.00 64.31  ? 531 LYS A CB  1 
ATOM   5870 C CG  . LYS B  1 531 ? 196.229 147.561 201.795 1.00 69.91  ? 531 LYS A CG  1 
ATOM   5871 C CD  . LYS B  1 531 ? 195.985 147.276 203.267 1.00 68.52  ? 531 LYS A CD  1 
ATOM   5872 C CE  . LYS B  1 531 ? 195.019 146.116 203.458 1.00 74.37  ? 531 LYS A CE  1 
ATOM   5873 N NZ  . LYS B  1 531 ? 195.525 144.852 202.857 1.00 74.00  ? 531 LYS A NZ  1 
ATOM   5874 N N   . MET B  1 532 ? 198.705 151.375 202.250 1.00 62.41  ? 532 MET A N   1 
ATOM   5875 C CA  . MET B  1 532 ? 199.730 152.001 203.072 1.00 58.08  ? 532 MET A CA  1 
ATOM   5876 C C   . MET B  1 532 ? 199.736 153.518 202.968 1.00 61.91  ? 532 MET A C   1 
ATOM   5877 O O   . MET B  1 532 ? 199.911 154.200 203.982 1.00 63.73  ? 532 MET A O   1 
ATOM   5878 C CB  . MET B  1 532 ? 201.103 151.456 202.684 1.00 55.03  ? 532 MET A CB  1 
ATOM   5879 C CG  . MET B  1 532 ? 201.203 149.956 202.840 1.00 63.56  ? 532 MET A CG  1 
ATOM   5880 S SD  . MET B  1 532 ? 201.892 149.500 204.431 1.00 77.76  ? 532 MET A SD  1 
ATOM   5881 C CE  . MET B  1 532 ? 203.613 149.394 203.986 1.00 60.84  ? 532 MET A CE  1 
ATOM   5882 N N   . ASP B  1 533 ? 199.560 154.065 201.763 1.00 54.10  ? 533 ASP A N   1 
ATOM   5883 C CA  . ASP B  1 533 ? 199.480 155.514 201.618 1.00 47.13  ? 533 ASP A CA  1 
ATOM   5884 C C   . ASP B  1 533 ? 198.263 156.068 202.344 1.00 58.26  ? 533 ASP A C   1 
ATOM   5885 O O   . ASP B  1 533 ? 198.374 156.998 203.149 1.00 66.16  ? 533 ASP A O   1 
ATOM   5886 C CB  . ASP B  1 533 ? 199.439 155.892 200.138 1.00 41.54  ? 533 ASP A CB  1 
ATOM   5887 C CG  . ASP B  1 533 ? 200.814 155.954 199.514 1.00 53.00  ? 533 ASP A CG  1 
ATOM   5888 O OD1 . ASP B  1 533 ? 201.810 155.856 200.259 1.00 59.52  ? 533 ASP A OD1 1 
ATOM   5889 O OD2 . ASP B  1 533 ? 200.902 156.103 198.278 1.00 55.89  ? 533 ASP A OD2 1 
ATOM   5890 N N   . TRP B  1 534 ? 197.090 155.499 202.078 1.00 51.83  ? 534 TRP A N   1 
ATOM   5891 C CA  . TRP B  1 534 ? 195.856 155.985 202.680 1.00 44.96  ? 534 TRP A CA  1 
ATOM   5892 C C   . TRP B  1 534 ? 195.514 155.276 203.980 1.00 52.36  ? 534 TRP A C   1 
ATOM   5893 O O   . TRP B  1 534 ? 194.800 155.842 204.815 1.00 54.55  ? 534 TRP A O   1 
ATOM   5894 C CB  . TRP B  1 534 ? 194.693 155.825 201.699 1.00 50.49  ? 534 TRP A CB  1 
ATOM   5895 C CG  . TRP B  1 534 ? 194.837 156.636 200.454 1.00 46.98  ? 534 TRP A CG  1 
ATOM   5896 C CD1 . TRP B  1 534 ? 195.864 157.468 200.133 1.00 51.11  ? 534 TRP A CD1 1 
ATOM   5897 C CD2 . TRP B  1 534 ? 193.925 156.680 199.353 1.00 47.37  ? 534 TRP A CD2 1 
ATOM   5898 N NE1 . TRP B  1 534 ? 195.647 158.035 198.904 1.00 49.29  ? 534 TRP A NE1 1 
ATOM   5899 C CE2 . TRP B  1 534 ? 194.463 157.565 198.403 1.00 44.05  ? 534 TRP A CE2 1 
ATOM   5900 C CE3 . TRP B  1 534 ? 192.705 156.059 199.080 1.00 50.20  ? 534 TRP A CE3 1 
ATOM   5901 C CZ2 . TRP B  1 534 ? 193.824 157.846 197.203 1.00 49.63  ? 534 TRP A CZ2 1 
ATOM   5902 C CZ3 . TRP B  1 534 ? 192.073 156.338 197.888 1.00 49.63  ? 534 TRP A CZ3 1 
ATOM   5903 C CH2 . TRP B  1 534 ? 192.633 157.223 196.964 1.00 54.61  ? 534 TRP A CH2 1 
ATOM   5904 N N   . GLY B  1 535 ? 196.006 154.055 204.174 1.00 65.23  ? 535 GLY A N   1 
ATOM   5905 C CA  . GLY B  1 535 ? 195.664 153.285 205.350 1.00 67.03  ? 535 GLY A CA  1 
ATOM   5906 C C   . GLY B  1 535 ? 194.317 152.606 205.297 1.00 70.34  ? 535 GLY A C   1 
ATOM   5907 O O   . GLY B  1 535 ? 193.870 152.073 206.319 1.00 74.06  ? 535 GLY A O   1 
ATOM   5908 N N   . LEU B  1 536 ? 193.658 152.602 204.143 1.00 70.65  ? 536 LEU A N   1 
ATOM   5909 C CA  . LEU B  1 536 ? 192.326 152.035 204.024 1.00 74.62  ? 536 LEU A CA  1 
ATOM   5910 C C   . LEU B  1 536 ? 192.402 150.509 203.991 1.00 76.21  ? 536 LEU A C   1 
ATOM   5911 O O   . LEU B  1 536 ? 193.478 149.910 204.067 1.00 75.75  ? 536 LEU A O   1 
ATOM   5912 C CB  . LEU B  1 536 ? 191.629 152.588 202.783 1.00 73.64  ? 536 LEU A CB  1 
ATOM   5913 C CG  . LEU B  1 536 ? 191.543 154.114 202.711 1.00 65.34  ? 536 LEU A CG  1 
ATOM   5914 C CD1 . LEU B  1 536 ? 190.639 154.551 201.575 1.00 64.41  ? 536 LEU A CD1 1 
ATOM   5915 C CD2 . LEU B  1 536 ? 191.062 154.692 204.031 1.00 64.17  ? 536 LEU A CD2 1 
ATOM   5916 N N   . PHE B  1 537 ? 191.233 149.873 203.879 1.00 75.74  ? 537 PHE A N   1 
ATOM   5917 C CA  . PHE B  1 537 ? 191.109 148.414 203.924 1.00 73.17  ? 537 PHE A CA  1 
ATOM   5918 C C   . PHE B  1 537 ? 191.689 147.845 205.214 1.00 76.57  ? 537 PHE A C   1 
ATOM   5919 O O   . PHE B  1 537 ? 192.218 146.732 205.233 1.00 80.44  ? 537 PHE A O   1 
ATOM   5920 C CB  . PHE B  1 537 ? 191.762 147.736 202.710 1.00 72.76  ? 537 PHE A CB  1 
ATOM   5921 C CG  . PHE B  1 537 ? 191.158 148.111 201.375 1.00 76.34  ? 537 PHE A CG  1 
ATOM   5922 C CD1 . PHE B  1 537 ? 191.497 147.397 200.238 1.00 77.11  ? 537 PHE A CD1 1 
ATOM   5923 C CD2 . PHE B  1 537 ? 190.239 149.140 201.254 1.00 78.07  ? 537 PHE A CD2 1 
ATOM   5924 C CE1 . PHE B  1 537 ? 190.953 147.717 199.010 1.00 78.74  ? 537 PHE A CE1 1 
ATOM   5925 C CE2 . PHE B  1 537 ? 189.693 149.463 200.030 1.00 76.11  ? 537 PHE A CE2 1 
ATOM   5926 C CZ  . PHE B  1 537 ? 190.049 148.751 198.907 1.00 77.60  ? 537 PHE A CZ  1 
ATOM   5927 N N   . ASP B  1 538 ? 191.593 148.604 206.302 1.00 87.30  ? 538 ASP A N   1 
ATOM   5928 C CA  . ASP B  1 538 ? 192.159 148.180 207.573 1.00 92.53  ? 538 ASP A CA  1 
ATOM   5929 C C   . ASP B  1 538 ? 191.261 147.135 208.222 1.00 94.64  ? 538 ASP A C   1 
ATOM   5930 O O   . ASP B  1 538 ? 190.031 147.225 208.160 1.00 94.81  ? 538 ASP A O   1 
ATOM   5931 C CB  . ASP B  1 538 ? 192.354 149.390 208.491 1.00 92.41  ? 538 ASP A CB  1 
ATOM   5932 C CG  . ASP B  1 538 ? 192.572 149.007 209.945 1.00 97.52  ? 538 ASP A CG  1 
ATOM   5933 O OD1 . ASP B  1 538 ? 191.608 148.585 210.617 1.00 99.87  ? 538 ASP A OD1 1 
ATOM   5934 O OD2 . ASP B  1 538 ? 193.721 149.128 210.418 1.00 96.54  ? 538 ASP A OD2 1 
ATOM   5935 N N   . LYS B  1 539 ? 191.889 146.136 208.847 1.00 100.54 ? 539 LYS A N   1 
ATOM   5936 C CA  . LYS B  1 539 ? 191.139 145.012 209.399 1.00 102.47 ? 539 LYS A CA  1 
ATOM   5937 C C   . LYS B  1 539 ? 190.223 145.449 210.536 1.00 103.58 ? 539 LYS A C   1 
ATOM   5938 O O   . LYS B  1 539 ? 189.075 144.999 210.622 1.00 102.93 ? 539 LYS A O   1 
ATOM   5939 C CB  . LYS B  1 539 ? 192.104 143.929 209.879 1.00 102.77 ? 539 LYS A CB  1 
ATOM   5940 C CG  . LYS B  1 539 ? 193.208 143.597 208.891 1.00 102.42 ? 539 LYS A CG  1 
ATOM   5941 C CD  . LYS B  1 539 ? 194.263 142.705 209.525 1.00 100.45 ? 539 LYS A CD  1 
ATOM   5942 C CE  . LYS B  1 539 ? 195.396 142.412 208.555 1.00 100.24 ? 539 LYS A CE  1 
ATOM   5943 N NZ  . LYS B  1 539 ? 196.465 141.592 209.190 1.00 100.41 ? 539 LYS A NZ  1 
ATOM   5944 N N   . ASN B  1 540 ? 190.708 146.324 211.416 1.00 109.42 ? 540 ASN A N   1 
ATOM   5945 C CA  . ASN B  1 540 ? 189.971 146.728 212.607 1.00 108.52 ? 540 ASN A CA  1 
ATOM   5946 C C   . ASN B  1 540 ? 189.035 147.904 212.361 1.00 109.36 ? 540 ASN A C   1 
ATOM   5947 O O   . ASN B  1 540 ? 188.701 148.620 213.313 1.00 108.85 ? 540 ASN A O   1 
ATOM   5948 C CB  . ASN B  1 540 ? 190.948 147.067 213.735 1.00 105.45 ? 540 ASN A CB  1 
ATOM   5949 C CG  . ASN B  1 540 ? 192.189 146.197 213.708 1.00 109.00 ? 540 ASN A CG  1 
ATOM   5950 O OD1 . ASN B  1 540 ? 192.953 146.214 212.743 1.00 108.55 ? 540 ASN A OD1 1 
ATOM   5951 N ND2 . ASN B  1 540 ? 192.390 145.421 214.766 1.00 110.21 ? 540 ASN A ND2 1 
ATOM   5952 N N   . ALA B  1 541 ? 188.611 148.122 211.113 1.00 104.26 ? 541 ALA A N   1 
ATOM   5953 C CA  . ALA B  1 541 ? 187.719 149.240 210.820 1.00 101.68 ? 541 ALA A CA  1 
ATOM   5954 C C   . ALA B  1 541 ? 186.384 149.089 211.537 1.00 103.67 ? 541 ALA A C   1 
ATOM   5955 O O   . ALA B  1 541 ? 185.850 150.064 212.080 1.00 100.60 ? 541 ALA A O   1 
ATOM   5956 C CB  . ALA B  1 541 ? 187.506 149.360 209.312 1.00 100.17 ? 541 ALA A CB  1 
ATOM   5957 N N   . GLY B  1 542 ? 185.829 147.880 211.551 1.00 113.34 ? 542 GLY A N   1 
ATOM   5958 C CA  . GLY B  1 542 ? 184.570 147.641 212.227 1.00 113.93 ? 542 GLY A CA  1 
ATOM   5959 C C   . GLY B  1 542 ? 183.370 148.194 211.487 1.00 113.31 ? 542 GLY A C   1 
ATOM   5960 O O   . GLY B  1 542 ? 182.969 147.656 210.450 1.00 111.49 ? 542 GLY A O   1 
ATOM   5961 N N   . GLU B  1 543 ? 182.785 149.270 212.019 1.00 111.53 ? 543 GLU A N   1 
ATOM   5962 C CA  . GLU B  1 543 ? 181.593 149.848 211.405 1.00 111.58 ? 543 GLU A CA  1 
ATOM   5963 C C   . GLU B  1 543 ? 181.886 150.362 209.999 1.00 112.45 ? 543 GLU A C   1 
ATOM   5964 O O   . GLU B  1 543 ? 181.050 150.234 209.098 1.00 110.21 ? 543 GLU A O   1 
ATOM   5965 C CB  . GLU B  1 543 ? 181.026 150.960 212.295 1.00 109.47 ? 543 GLU A CB  1 
ATOM   5966 C CG  . GLU B  1 543 ? 181.819 152.267 212.327 1.00 108.99 ? 543 GLU A CG  1 
ATOM   5967 C CD  . GLU B  1 543 ? 183.222 152.111 212.889 1.00 108.67 ? 543 GLU A CD  1 
ATOM   5968 O OE1 . GLU B  1 543 ? 183.481 151.115 213.597 1.00 107.20 ? 543 GLU A OE1 1 
ATOM   5969 O OE2 . GLU B  1 543 ? 184.069 152.988 212.619 1.00 108.71 ? 543 GLU A OE2 1 
ATOM   5970 N N   . ASN B  1 544 ? 183.063 150.946 209.791 1.00 103.27 ? 544 ASN A N   1 
ATOM   5971 C CA  . ASN B  1 544 ? 183.461 151.355 208.452 1.00 99.59  ? 544 ASN A CA  1 
ATOM   5972 C C   . ASN B  1 544 ? 183.790 150.131 207.609 1.00 101.23 ? 544 ASN A C   1 
ATOM   5973 O O   . ASN B  1 544 ? 184.480 149.213 208.060 1.00 103.65 ? 544 ASN A O   1 
ATOM   5974 C CB  . ASN B  1 544 ? 184.664 152.294 208.516 1.00 100.11 ? 544 ASN A CB  1 
ATOM   5975 C CG  . ASN B  1 544 ? 184.380 153.546 209.318 1.00 101.99 ? 544 ASN A CG  1 
ATOM   5976 O OD1 . ASN B  1 544 ? 183.242 154.006 209.389 1.00 100.24 ? 544 ASN A OD1 1 
ATOM   5977 N ND2 . ASN B  1 544 ? 185.417 154.105 209.929 1.00 103.00 ? 544 ASN A ND2 1 
ATOM   5978 N N   . THR B  1 545 ? 183.289 150.117 206.379 1.00 95.28  ? 545 THR A N   1 
ATOM   5979 C CA  . THR B  1 545 ? 183.471 148.988 205.476 1.00 98.62  ? 545 THR A CA  1 
ATOM   5980 C C   . THR B  1 545 ? 184.583 149.316 204.489 1.00 94.35  ? 545 THR A C   1 
ATOM   5981 O O   . THR B  1 545 ? 184.519 150.335 203.794 1.00 89.68  ? 545 THR A O   1 
ATOM   5982 C CB  . THR B  1 545 ? 182.174 148.665 204.735 1.00 99.05  ? 545 THR A CB  1 
ATOM   5983 O OG1 . THR B  1 545 ? 182.062 149.500 203.575 1.00 98.29  ? 545 THR A OG1 1 
ATOM   5984 C CG2 . THR B  1 545 ? 180.972 148.900 205.639 1.00 95.61  ? 545 THR A CG2 1 
ATOM   5985 N N   . PHE B  1 546 ? 185.595 148.447 204.428 1.00 94.74  ? 546 PHE A N   1 
ATOM   5986 C CA  . PHE B  1 546 ? 186.731 148.612 203.520 1.00 96.98  ? 546 PHE A CA  1 
ATOM   5987 C C   . PHE B  1 546 ? 187.408 149.967 203.715 1.00 98.21  ? 546 PHE A C   1 
ATOM   5988 O O   . PHE B  1 546 ? 187.826 150.615 202.755 1.00 100.94 ? 546 PHE A O   1 
ATOM   5989 C CB  . PHE B  1 546 ? 186.306 148.429 202.061 1.00 98.22  ? 546 PHE A CB  1 
ATOM   5990 C CG  . PHE B  1 546 ? 185.255 147.377 201.864 1.00 101.17 ? 546 PHE A CG  1 
ATOM   5991 C CD1 . PHE B  1 546 ? 185.589 146.034 201.883 1.00 100.52 ? 546 PHE A CD1 1 
ATOM   5992 C CD2 . PHE B  1 546 ? 183.934 147.731 201.653 1.00 100.71 ? 546 PHE A CD2 1 
ATOM   5993 C CE1 . PHE B  1 546 ? 184.623 145.065 201.700 1.00 99.76  ? 546 PHE A CE1 1 
ATOM   5994 C CE2 . PHE B  1 546 ? 182.965 146.768 201.470 1.00 99.74  ? 546 PHE A CE2 1 
ATOM   5995 C CZ  . PHE B  1 546 ? 183.309 145.433 201.493 1.00 100.36 ? 546 PHE A CZ  1 
ATOM   5996 N N   . LEU B  1 547 ? 187.522 150.392 204.967 1.00 90.96  ? 547 LEU A N   1 
ATOM   5997 C CA  . LEU B  1 547 ? 188.067 151.705 205.299 1.00 89.56  ? 547 LEU A CA  1 
ATOM   5998 C C   . LEU B  1 547 ? 188.951 151.548 206.531 1.00 90.68  ? 547 LEU A C   1 
ATOM   5999 O O   . LEU B  1 547 ? 189.363 150.442 206.893 1.00 96.10  ? 547 LEU A O   1 
ATOM   6000 C CB  . LEU B  1 547 ? 186.939 152.726 205.510 1.00 88.15  ? 547 LEU A CB  1 
ATOM   6001 C CG  . LEU B  1 547 ? 186.362 153.408 204.271 1.00 87.36  ? 547 LEU A CG  1 
ATOM   6002 C CD1 . LEU B  1 547 ? 185.625 154.672 204.671 1.00 86.08  ? 547 LEU A CD1 1 
ATOM   6003 C CD2 . LEU B  1 547 ? 187.458 153.717 203.268 1.00 84.13  ? 547 LEU A CD2 1 
ATOM   6004 N N   . ARG B  1 548 ? 189.264 152.666 207.174 1.00 75.61  ? 548 ARG A N   1 
ATOM   6005 C CA  . ARG B  1 548 ? 190.051 152.672 208.397 1.00 78.04  ? 548 ARG A CA  1 
ATOM   6006 C C   . ARG B  1 548 ? 189.144 152.830 209.613 1.00 78.37  ? 548 ARG A C   1 
ATOM   6007 O O   . ARG B  1 548 ? 187.957 153.147 209.501 1.00 81.65  ? 548 ARG A O   1 
ATOM   6008 C CB  . ARG B  1 548 ? 191.089 153.791 208.354 1.00 75.29  ? 548 ARG A CB  1 
ATOM   6009 C CG  . ARG B  1 548 ? 192.431 153.417 208.940 1.00 76.11  ? 548 ARG A CG  1 
ATOM   6010 C CD  . ARG B  1 548 ? 193.478 154.476 208.639 1.00 76.53  ? 548 ARG A CD  1 
ATOM   6011 N NE  . ARG B  1 548 ? 192.944 155.827 208.761 1.00 78.37  ? 548 ARG A NE  1 
ATOM   6012 C CZ  . ARG B  1 548 ? 192.633 156.602 207.732 1.00 73.35  ? 548 ARG A CZ  1 
ATOM   6013 N NH1 . ARG B  1 548 ? 192.801 156.195 206.486 1.00 69.44  ? 548 ARG A NH1 1 
ATOM   6014 N NH2 . ARG B  1 548 ? 192.133 157.811 207.960 1.00 70.53  ? 548 ARG A NH2 1 
ATOM   6015 N N   . GLU B  1 549 ? 189.725 152.607 210.795 1.00 91.46  ? 549 GLU A N   1 
ATOM   6016 C CA  . GLU B  1 549 ? 188.951 152.721 212.027 1.00 94.66  ? 549 GLU A CA  1 
ATOM   6017 C C   . GLU B  1 549 ? 188.670 154.175 212.382 1.00 91.82  ? 549 GLU A C   1 
ATOM   6018 O O   . GLU B  1 549 ? 187.610 154.482 212.940 1.00 90.38  ? 549 GLU A O   1 
ATOM   6019 C CB  . GLU B  1 549 ? 189.683 152.034 213.181 1.00 96.14  ? 549 GLU A CB  1 
ATOM   6020 C CG  . GLU B  1 549 ? 191.127 152.464 213.350 1.00 96.94  ? 549 GLU A CG  1 
ATOM   6021 C CD  . GLU B  1 549 ? 191.972 151.402 214.024 1.00 100.35 ? 549 GLU A CD  1 
ATOM   6022 O OE1 . GLU B  1 549 ? 191.481 150.268 214.192 1.00 97.49  ? 549 GLU A OE1 1 
ATOM   6023 O OE2 . GLU B  1 549 ? 193.125 151.706 214.392 1.00 101.12 ? 549 GLU A OE2 1 
ATOM   6024 N N   . GLU B  1 550 ? 189.594 155.077 212.064 1.00 85.64  ? 550 GLU A N   1 
ATOM   6025 C CA  . GLU B  1 550 ? 189.458 156.496 212.360 1.00 85.46  ? 550 GLU A CA  1 
ATOM   6026 C C   . GLU B  1 550 ? 189.442 157.297 211.066 1.00 81.84  ? 550 GLU A C   1 
ATOM   6027 O O   . GLU B  1 550 ? 190.274 157.083 210.179 1.00 83.71  ? 550 GLU A O   1 
ATOM   6028 C CB  . GLU B  1 550 ? 190.597 156.987 213.260 1.00 84.88  ? 550 GLU A CB  1 
ATOM   6029 C CG  . GLU B  1 550 ? 190.348 158.348 213.895 1.00 85.39  ? 550 GLU A CG  1 
ATOM   6030 C CD  . GLU B  1 550 ? 191.478 158.781 214.811 1.00 88.99  ? 550 GLU A CD  1 
ATOM   6031 O OE1 . GLU B  1 550 ? 192.385 157.961 215.064 1.00 89.33  ? 550 GLU A OE1 1 
ATOM   6032 O OE2 . GLU B  1 550 ? 191.466 159.944 215.268 1.00 86.90  ? 550 GLU A OE2 1 
ATOM   6033 N N   . ILE B  1 551 ? 188.490 158.219 210.966 1.00 73.93  ? 551 ILE A N   1 
ATOM   6034 C CA  . ILE B  1 551 ? 188.349 159.095 209.809 1.00 77.18  ? 551 ILE A CA  1 
ATOM   6035 C C   . ILE B  1 551 ? 188.158 160.520 210.307 1.00 77.44  ? 551 ILE A C   1 
ATOM   6036 O O   . ILE B  1 551 ? 187.407 160.760 211.258 1.00 77.78  ? 551 ILE A O   1 
ATOM   6037 C CB  . ILE B  1 551 ? 187.176 158.658 208.908 1.00 76.07  ? 551 ILE A CB  1 
ATOM   6038 C CG1 . ILE B  1 551 ? 185.926 158.402 209.753 1.00 79.73  ? 551 ILE A CG1 1 
ATOM   6039 C CG2 . ILE B  1 551 ? 187.548 157.423 208.107 1.00 72.27  ? 551 ILE A CG2 1 
ATOM   6040 C CD1 . ILE B  1 551 ? 184.754 157.869 208.965 1.00 80.76  ? 551 ILE A CD1 1 
ATOM   6041 N N   . VAL B  1 552 ? 188.848 161.465 209.674 1.00 69.20  ? 552 VAL A N   1 
ATOM   6042 C CA  . VAL B  1 552 ? 188.769 162.862 210.077 1.00 66.65  ? 552 VAL A CA  1 
ATOM   6043 C C   . VAL B  1 552 ? 187.975 163.712 209.092 1.00 70.12  ? 552 VAL A C   1 
ATOM   6044 O O   . VAL B  1 552 ? 187.585 164.835 209.447 1.00 71.48  ? 552 VAL A O   1 
ATOM   6045 C CB  . VAL B  1 552 ? 190.175 163.462 210.289 1.00 61.75  ? 552 VAL A CB  1 
ATOM   6046 C CG1 . VAL B  1 552 ? 190.774 163.903 208.968 1.00 63.86  ? 552 VAL A CG1 1 
ATOM   6047 C CG2 . VAL B  1 552 ? 190.128 164.612 211.287 1.00 68.14  ? 552 VAL A CG2 1 
ATOM   6048 N N   . TYR B  1 553 ? 187.718 163.224 207.883 1.00 69.58  ? 553 TYR A N   1 
ATOM   6049 C CA  . TYR B  1 553 ? 186.947 164.002 206.927 1.00 73.04  ? 553 TYR A CA  1 
ATOM   6050 C C   . TYR B  1 553 ? 185.460 163.930 207.273 1.00 71.73  ? 553 TYR A C   1 
ATOM   6051 O O   . TYR B  1 553 ? 184.972 162.878 207.696 1.00 72.23  ? 553 TYR A O   1 
ATOM   6052 C CB  . TYR B  1 553 ? 187.200 163.505 205.506 1.00 66.53  ? 553 TYR A CB  1 
ATOM   6053 C CG  . TYR B  1 553 ? 188.580 163.867 205.005 1.00 65.32  ? 553 TYR A CG  1 
ATOM   6054 C CD1 . TYR B  1 553 ? 189.397 164.716 205.736 1.00 62.64  ? 553 TYR A CD1 1 
ATOM   6055 C CD2 . TYR B  1 553 ? 189.069 163.360 203.811 1.00 69.21  ? 553 TYR A CD2 1 
ATOM   6056 C CE1 . TYR B  1 553 ? 190.655 165.051 205.299 1.00 58.91  ? 553 TYR A CE1 1 
ATOM   6057 C CE2 . TYR B  1 553 ? 190.334 163.694 203.365 1.00 76.28  ? 553 TYR A CE2 1 
ATOM   6058 C CZ  . TYR B  1 553 ? 191.120 164.542 204.117 1.00 66.73  ? 553 TYR A CZ  1 
ATOM   6059 O OH  . TYR B  1 553 ? 192.380 164.888 203.695 1.00 63.70  ? 553 TYR A OH  1 
ATOM   6060 N N   . PRO B  1 554 ? 184.721 165.032 207.112 1.00 78.40  ? 554 PRO A N   1 
ATOM   6061 C CA  . PRO B  1 554 ? 183.346 165.074 207.644 1.00 81.31  ? 554 PRO A CA  1 
ATOM   6062 C C   . PRO B  1 554 ? 182.414 164.031 207.054 1.00 81.23  ? 554 PRO A C   1 
ATOM   6063 O O   . PRO B  1 554 ? 181.557 163.501 207.772 1.00 81.90  ? 554 PRO A O   1 
ATOM   6064 C CB  . PRO B  1 554 ? 182.891 166.501 207.303 1.00 81.20  ? 554 PRO A CB  1 
ATOM   6065 C CG  . PRO B  1 554 ? 183.734 166.898 206.138 1.00 81.34  ? 554 PRO A CG  1 
ATOM   6066 C CD  . PRO B  1 554 ? 185.068 166.258 206.373 1.00 78.34  ? 554 PRO A CD  1 
ATOM   6067 N N   . GLN B  1 555 ? 182.551 163.717 205.771 1.00 77.94  ? 555 GLN A N   1 
ATOM   6068 C CA  . GLN B  1 555 ? 181.648 162.801 205.087 1.00 79.85  ? 555 GLN A CA  1 
ATOM   6069 C C   . GLN B  1 555 ? 182.378 161.502 204.782 1.00 78.85  ? 555 GLN A C   1 
ATOM   6070 O O   . GLN B  1 555 ? 183.485 161.521 204.237 1.00 82.14  ? 555 GLN A O   1 
ATOM   6071 C CB  . GLN B  1 555 ? 181.110 163.425 203.798 1.00 79.34  ? 555 GLN A CB  1 
ATOM   6072 C CG  . GLN B  1 555 ? 179.623 163.212 203.576 1.00 81.78  ? 555 GLN A CG  1 
ATOM   6073 C CD  . GLN B  1 555 ? 178.774 164.244 204.291 1.00 85.01  ? 555 GLN A CD  1 
ATOM   6074 O OE1 . GLN B  1 555 ? 179.042 165.443 204.218 1.00 82.14  ? 555 GLN A OE1 1 
ATOM   6075 N NE2 . GLN B  1 555 ? 177.744 163.782 204.990 1.00 82.70  ? 555 GLN A NE2 1 
ATOM   6076 N N   . LYS B  1 556 ? 181.754 160.376 205.133 1.00 75.86  ? 556 LYS A N   1 
ATOM   6077 C CA  . LYS B  1 556 ? 182.371 159.080 204.884 1.00 74.90  ? 556 LYS A CA  1 
ATOM   6078 C C   . LYS B  1 556 ? 182.321 158.685 203.415 1.00 76.30  ? 556 LYS A C   1 
ATOM   6079 O O   . LYS B  1 556 ? 183.084 157.808 202.999 1.00 80.18  ? 556 LYS A O   1 
ATOM   6080 C CB  . LYS B  1 556 ? 181.694 158.003 205.732 1.00 81.16  ? 556 LYS A CB  1 
ATOM   6081 C CG  . LYS B  1 556 ? 182.603 156.844 206.100 1.00 80.63  ? 556 LYS A CG  1 
ATOM   6082 C CD  . LYS B  1 556 ? 181.886 155.845 206.991 1.00 81.27  ? 556 LYS A CD  1 
ATOM   6083 C CE  . LYS B  1 556 ? 181.397 156.498 208.273 1.00 80.75  ? 556 LYS A CE  1 
ATOM   6084 N NZ  . LYS B  1 556 ? 180.749 155.514 209.183 1.00 80.14  ? 556 LYS A NZ  1 
ATOM   6085 N N   . ALA B  1 557 ? 181.450 159.310 202.621 1.00 71.20  ? 557 ALA A N   1 
ATOM   6086 C CA  . ALA B  1 557 ? 181.368 158.979 201.203 1.00 73.08  ? 557 ALA A CA  1 
ATOM   6087 C C   . ALA B  1 557 ? 182.589 159.450 200.427 1.00 72.73  ? 557 ALA A C   1 
ATOM   6088 O O   . ALA B  1 557 ? 182.829 158.961 199.315 1.00 73.36  ? 557 ALA A O   1 
ATOM   6089 C CB  . ALA B  1 557 ? 180.102 159.583 200.596 1.00 72.68  ? 557 ALA A CB  1 
ATOM   6090 N N   . TYR B  1 558 ? 183.359 160.387 200.986 1.00 59.88  ? 558 TYR A N   1 
ATOM   6091 C CA  . TYR B  1 558 ? 184.560 160.865 200.311 1.00 59.07  ? 558 TYR A CA  1 
ATOM   6092 C C   . TYR B  1 558 ? 185.549 159.729 200.086 1.00 64.79  ? 558 TYR A C   1 
ATOM   6093 O O   . TYR B  1 558 ? 186.091 159.575 198.988 1.00 65.71  ? 558 TYR A O   1 
ATOM   6094 C CB  . TYR B  1 558 ? 185.210 161.982 201.125 1.00 61.30  ? 558 TYR A CB  1 
ATOM   6095 C CG  . TYR B  1 558 ? 184.408 163.259 201.183 1.00 64.03  ? 558 TYR A CG  1 
ATOM   6096 C CD1 . TYR B  1 558 ? 183.547 163.608 200.155 1.00 62.11  ? 558 TYR A CD1 1 
ATOM   6097 C CD2 . TYR B  1 558 ? 184.518 164.118 202.266 1.00 68.41  ? 558 TYR A CD2 1 
ATOM   6098 C CE1 . TYR B  1 558 ? 182.816 164.776 200.205 1.00 68.51  ? 558 TYR A CE1 1 
ATOM   6099 C CE2 . TYR B  1 558 ? 183.792 165.288 202.325 1.00 65.12  ? 558 TYR A CE2 1 
ATOM   6100 C CZ  . TYR B  1 558 ? 182.942 165.612 201.293 1.00 70.06  ? 558 TYR A CZ  1 
ATOM   6101 O OH  . TYR B  1 558 ? 182.217 166.779 201.351 1.00 73.11  ? 558 TYR A OH  1 
ATOM   6102 N N   . TYR B  1 559 ? 185.788 158.917 201.117 1.00 59.00  ? 559 TYR A N   1 
ATOM   6103 C CA  . TYR B  1 559 ? 186.721 157.803 200.979 1.00 55.52  ? 559 TYR A CA  1 
ATOM   6104 C C   . TYR B  1 559 ? 186.230 156.794 199.949 1.00 66.16  ? 559 TYR A C   1 
ATOM   6105 O O   . TYR B  1 559 ? 187.016 156.291 199.137 1.00 77.01  ? 559 TYR A O   1 
ATOM   6106 C CB  . TYR B  1 559 ? 186.931 157.110 202.325 1.00 54.11  ? 559 TYR A CB  1 
ATOM   6107 C CG  . TYR B  1 559 ? 187.414 157.994 203.452 1.00 52.58  ? 559 TYR A CG  1 
ATOM   6108 C CD1 . TYR B  1 559 ? 186.563 158.893 204.075 1.00 60.52  ? 559 TYR A CD1 1 
ATOM   6109 C CD2 . TYR B  1 559 ? 188.719 157.907 203.911 1.00 61.74  ? 559 TYR A CD2 1 
ATOM   6110 C CE1 . TYR B  1 559 ? 187.002 159.691 205.110 1.00 63.70  ? 559 TYR A CE1 1 
ATOM   6111 C CE2 . TYR B  1 559 ? 189.166 158.700 204.945 1.00 63.17  ? 559 TYR A CE2 1 
ATOM   6112 C CZ  . TYR B  1 559 ? 188.303 159.591 205.541 1.00 60.29  ? 559 TYR A CZ  1 
ATOM   6113 O OH  . TYR B  1 559 ? 188.745 160.384 206.574 1.00 60.08  ? 559 TYR A OH  1 
ATOM   6114 N N   . TYR B  1 560 ? 184.935 156.472 199.979 1.00 72.71  ? 560 TYR A N   1 
ATOM   6115 C CA  . TYR B  1 560 ? 184.401 155.472 199.060 1.00 72.02  ? 560 TYR A CA  1 
ATOM   6116 C C   . TYR B  1 560 ? 184.483 155.944 197.616 1.00 73.43  ? 560 TYR A C   1 
ATOM   6117 O O   . TYR B  1 560 ? 184.818 155.159 196.721 1.00 65.64  ? 560 TYR A O   1 
ATOM   6118 C CB  . TYR B  1 560 ? 182.962 155.126 199.435 1.00 71.86  ? 560 TYR A CB  1 
ATOM   6119 C CG  . TYR B  1 560 ? 182.834 154.523 200.810 1.00 72.25  ? 560 TYR A CG  1 
ATOM   6120 C CD1 . TYR B  1 560 ? 183.411 153.298 201.104 1.00 75.44  ? 560 TYR A CD1 1 
ATOM   6121 C CD2 . TYR B  1 560 ? 182.138 155.178 201.815 1.00 71.94  ? 560 TYR A CD2 1 
ATOM   6122 C CE1 . TYR B  1 560 ? 183.301 152.742 202.359 1.00 75.79  ? 560 TYR A CE1 1 
ATOM   6123 C CE2 . TYR B  1 560 ? 182.023 154.630 203.076 1.00 73.97  ? 560 TYR A CE2 1 
ATOM   6124 C CZ  . TYR B  1 560 ? 182.607 153.411 203.342 1.00 77.88  ? 560 TYR A CZ  1 
ATOM   6125 O OH  . TYR B  1 560 ? 182.495 152.856 204.596 1.00 77.91  ? 560 TYR A OH  1 
ATOM   6126 N N   . CYS B  1 561 ? 184.176 157.218 197.361 1.00 72.29  ? 561 CYS A N   1 
ATOM   6127 C CA  . CYS B  1 561 ? 184.313 157.724 196.001 1.00 74.41  ? 561 CYS A CA  1 
ATOM   6128 C C   . CYS B  1 561 ? 185.777 157.843 195.598 1.00 78.34  ? 561 CYS A C   1 
ATOM   6129 O O   . CYS B  1 561 ? 186.119 157.611 194.432 1.00 84.14  ? 561 CYS A O   1 
ATOM   6130 C CB  . CYS B  1 561 ? 183.603 159.070 195.858 1.00 74.93  ? 561 CYS A CB  1 
ATOM   6131 S SG  . CYS B  1 561 ? 184.563 160.490 196.404 1.00 88.72  ? 561 CYS A SG  1 
ATOM   6132 N N   . ALA B  1 562 ? 186.656 158.173 196.547 1.00 58.02  ? 562 ALA A N   1 
ATOM   6133 C CA  . ALA B  1 562 ? 188.073 158.304 196.236 1.00 56.33  ? 562 ALA A CA  1 
ATOM   6134 C C   . ALA B  1 562 ? 188.709 156.963 195.909 1.00 57.23  ? 562 ALA A C   1 
ATOM   6135 O O   . ALA B  1 562 ? 189.639 156.910 195.102 1.00 66.74  ? 562 ALA A O   1 
ATOM   6136 C CB  . ALA B  1 562 ? 188.808 158.960 197.400 1.00 55.19  ? 562 ALA A CB  1 
ATOM   6137 N N   . ILE B  1 563 ? 188.243 155.879 196.529 1.00 51.65  ? 563 ILE A N   1 
ATOM   6138 C CA  . ILE B  1 563 ? 188.779 154.559 196.202 1.00 48.69  ? 563 ILE A CA  1 
ATOM   6139 C C   . ILE B  1 563 ? 188.494 154.223 194.743 1.00 57.00  ? 563 ILE A C   1 
ATOM   6140 O O   . ILE B  1 563 ? 189.383 153.790 193.997 1.00 57.82  ? 563 ILE A O   1 
ATOM   6141 C CB  . ILE B  1 563 ? 188.200 153.493 197.147 1.00 42.91  ? 563 ILE A CB  1 
ATOM   6142 C CG1 . ILE B  1 563 ? 188.813 153.626 198.539 1.00 46.47  ? 563 ILE A CG1 1 
ATOM   6143 C CG2 . ILE B  1 563 ? 188.454 152.103 196.598 1.00 50.45  ? 563 ILE A CG2 1 
ATOM   6144 C CD1 . ILE B  1 563 ? 188.226 152.674 199.548 1.00 53.23  ? 563 ILE A CD1 1 
ATOM   6145 N N   . ILE B  1 564 ? 187.251 154.440 194.309 1.00 60.59  ? 564 ILE A N   1 
ATOM   6146 C CA  . ILE B  1 564 ? 186.887 154.180 192.920 1.00 60.24  ? 564 ILE A CA  1 
ATOM   6147 C C   . ILE B  1 564 ? 187.642 155.120 191.990 1.00 59.56  ? 564 ILE A C   1 
ATOM   6148 O O   . ILE B  1 564 ? 188.077 154.724 190.900 1.00 59.21  ? 564 ILE A O   1 
ATOM   6149 C CB  . ILE B  1 564 ? 185.362 154.300 192.740 1.00 57.02  ? 564 ILE A CB  1 
ATOM   6150 C CG1 . ILE B  1 564 ? 184.652 153.155 193.463 1.00 60.09  ? 564 ILE A CG1 1 
ATOM   6151 C CG2 . ILE B  1 564 ? 184.989 154.306 191.267 1.00 59.26  ? 564 ILE A CG2 1 
ATOM   6152 C CD1 . ILE B  1 564 ? 185.003 151.783 192.926 1.00 57.14  ? 564 ILE A CD1 1 
ATOM   6153 N N   . GLU B  1 565 ? 187.810 156.378 192.403 1.00 61.36  ? 565 GLU A N   1 
ATOM   6154 C CA  . GLU B  1 565 ? 188.555 157.331 191.588 1.00 60.84  ? 565 GLU A CA  1 
ATOM   6155 C C   . GLU B  1 565 ? 190.003 156.893 191.410 1.00 61.14  ? 565 GLU A C   1 
ATOM   6156 O O   . GLU B  1 565 ? 190.552 156.964 190.304 1.00 66.14  ? 565 GLU A O   1 
ATOM   6157 C CB  . GLU B  1 565 ? 188.482 158.718 192.221 1.00 56.41  ? 565 GLU A CB  1 
ATOM   6158 C CG  . GLU B  1 565 ? 189.165 159.806 191.423 1.00 62.92  ? 565 GLU A CG  1 
ATOM   6159 C CD  . GLU B  1 565 ? 190.601 160.006 191.840 1.00 60.67  ? 565 GLU A CD  1 
ATOM   6160 O OE1 . GLU B  1 565 ? 191.061 159.280 192.744 1.00 60.09  ? 565 GLU A OE1 1 
ATOM   6161 O OE2 . GLU B  1 565 ? 191.268 160.891 191.271 1.00 60.50  ? 565 GLU A OE2 1 
ATOM   6162 N N   . ASP B  1 566 ? 190.642 156.448 192.492 1.00 54.64  ? 566 ASP A N   1 
ATOM   6163 C CA  . ASP B  1 566 ? 192.017 155.975 192.402 1.00 51.87  ? 566 ASP A CA  1 
ATOM   6164 C C   . ASP B  1 566 ? 192.107 154.725 191.543 1.00 56.79  ? 566 ASP A C   1 
ATOM   6165 O O   . ASP B  1 566 ? 193.080 154.543 190.806 1.00 62.71  ? 566 ASP A O   1 
ATOM   6166 C CB  . ASP B  1 566 ? 192.575 155.707 193.799 1.00 50.01  ? 566 ASP A CB  1 
ATOM   6167 C CG  . ASP B  1 566 ? 194.089 155.693 193.829 1.00 58.17  ? 566 ASP A CG  1 
ATOM   6168 O OD1 . ASP B  1 566 ? 194.699 154.921 193.061 1.00 64.22  ? 566 ASP A OD1 1 
ATOM   6169 O OD2 . ASP B  1 566 ? 194.675 156.460 194.618 1.00 61.59  ? 566 ASP A OD2 1 
ATOM   6170 N N   . VAL B  1 567 ? 191.107 153.848 191.626 1.00 53.75  ? 567 VAL A N   1 
ATOM   6171 C CA  . VAL B  1 567 ? 191.119 152.643 190.801 1.00 57.53  ? 567 VAL A CA  1 
ATOM   6172 C C   . VAL B  1 567 ? 191.027 153.006 189.324 1.00 55.15  ? 567 VAL A C   1 
ATOM   6173 O O   . VAL B  1 567 ? 191.775 152.482 188.490 1.00 52.30  ? 567 VAL A O   1 
ATOM   6174 C CB  . VAL B  1 567 ? 189.987 151.690 191.223 1.00 57.87  ? 567 VAL A CB  1 
ATOM   6175 C CG1 . VAL B  1 567 ? 189.768 150.624 190.164 1.00 57.22  ? 567 VAL A CG1 1 
ATOM   6176 C CG2 . VAL B  1 567 ? 190.314 151.050 192.561 1.00 54.81  ? 567 VAL A CG2 1 
ATOM   6177 N N   . ILE B  1 568 ? 190.113 153.915 188.975 1.00 56.00  ? 568 ILE A N   1 
ATOM   6178 C CA  . ILE B  1 568 ? 189.908 154.236 187.564 1.00 57.68  ? 568 ILE A CA  1 
ATOM   6179 C C   . ILE B  1 568 ? 191.081 155.039 187.009 1.00 58.66  ? 568 ILE A C   1 
ATOM   6180 O O   . ILE B  1 568 ? 191.494 154.835 185.861 1.00 63.93  ? 568 ILE A O   1 
ATOM   6181 C CB  . ILE B  1 568 ? 188.562 154.958 187.348 1.00 55.17  ? 568 ILE A CB  1 
ATOM   6182 C CG1 . ILE B  1 568 ? 188.510 156.286 188.098 1.00 57.41  ? 568 ILE A CG1 1 
ATOM   6183 C CG2 . ILE B  1 568 ? 187.406 154.066 187.770 1.00 57.34  ? 568 ILE A CG2 1 
ATOM   6184 C CD1 . ILE B  1 568 ? 187.336 157.156 187.716 1.00 57.17  ? 568 ILE A CD1 1 
ATOM   6185 N N   . LEU B  1 569 ? 191.638 155.959 187.797 1.00 53.95  ? 569 LEU A N   1 
ATOM   6186 C CA  . LEU B  1 569 ? 192.734 156.800 187.333 1.00 52.48  ? 569 LEU A CA  1 
ATOM   6187 C C   . LEU B  1 569 ? 194.104 156.185 187.577 1.00 56.51  ? 569 LEU A C   1 
ATOM   6188 O O   . LEU B  1 569 ? 195.112 156.779 187.183 1.00 57.74  ? 569 LEU A O   1 
ATOM   6189 C CB  . LEU B  1 569 ? 192.663 158.176 188.000 1.00 53.24  ? 569 LEU A CB  1 
ATOM   6190 C CG  . LEU B  1 569 ? 191.529 159.080 187.521 1.00 54.54  ? 569 LEU A CG  1 
ATOM   6191 C CD1 . LEU B  1 569 ? 191.647 160.456 188.140 1.00 54.94  ? 569 LEU A CD1 1 
ATOM   6192 C CD2 . LEU B  1 569 ? 191.534 159.172 186.007 1.00 53.95  ? 569 LEU A CD2 1 
ATOM   6193 N N   . ARG B  1 570 ? 194.164 155.020 188.216 1.00 61.54  ? 570 ARG A N   1 
ATOM   6194 C CA  . ARG B  1 570 ? 195.420 154.325 188.452 1.00 57.18  ? 570 ARG A CA  1 
ATOM   6195 C C   . ARG B  1 570 ? 195.797 153.420 187.294 1.00 65.13  ? 570 ARG A C   1 
ATOM   6196 O O   . ARG B  1 570 ? 196.966 153.044 187.161 1.00 65.95  ? 570 ARG A O   1 
ATOM   6197 C CB  . ARG B  1 570 ? 195.324 153.501 189.737 1.00 54.88  ? 570 ARG A CB  1 
ATOM   6198 C CG  . ARG B  1 570 ? 196.646 153.240 190.411 1.00 56.80  ? 570 ARG A CG  1 
ATOM   6199 C CD  . ARG B  1 570 ? 197.541 154.454 190.346 1.00 58.33  ? 570 ARG A CD  1 
ATOM   6200 N NE  . ARG B  1 570 ? 198.335 154.584 191.559 1.00 63.77  ? 570 ARG A NE  1 
ATOM   6201 C CZ  . ARG B  1 570 ? 199.478 155.249 191.641 1.00 65.80  ? 570 ARG A CZ  1 
ATOM   6202 N NH1 . ARG B  1 570 ? 200.006 155.847 190.587 1.00 64.91  ? 570 ARG A NH1 1 
ATOM   6203 N NH2 . ARG B  1 570 ? 200.106 155.314 192.810 1.00 67.44  ? 570 ARG A NH2 1 
ATOM   6204 N N   . PHE B  1 571 ? 194.823 153.047 186.471 1.00 70.71  ? 571 PHE A N   1 
ATOM   6205 C CA  . PHE B  1 571 ? 195.089 152.343 185.227 1.00 71.76  ? 571 PHE A CA  1 
ATOM   6206 C C   . PHE B  1 571 ? 195.172 153.313 184.057 1.00 68.78  ? 571 PHE A C   1 
ATOM   6207 O O   . PHE B  1 571 ? 195.827 153.023 183.050 1.00 69.55  ? 571 PHE A O   1 
ATOM   6208 C CB  . PHE B  1 571 ? 194.003 151.294 184.980 1.00 69.72  ? 571 PHE A CB  1 
ATOM   6209 C CG  . PHE B  1 571 ? 194.129 150.085 185.858 1.00 64.42  ? 571 PHE A CG  1 
ATOM   6210 C CD1 . PHE B  1 571 ? 193.654 150.108 187.157 1.00 63.32  ? 571 PHE A CD1 1 
ATOM   6211 C CD2 . PHE B  1 571 ? 194.733 148.932 185.391 1.00 68.13  ? 571 PHE A CD2 1 
ATOM   6212 C CE1 . PHE B  1 571 ? 193.773 149.004 187.973 1.00 67.42  ? 571 PHE A CE1 1 
ATOM   6213 C CE2 . PHE B  1 571 ? 194.854 147.823 186.202 1.00 74.84  ? 571 PHE A CE2 1 
ATOM   6214 C CZ  . PHE B  1 571 ? 194.373 147.860 187.495 1.00 73.12  ? 571 PHE A CZ  1 
ATOM   6215 N N   . ALA B  1 572 ? 194.516 154.468 184.184 1.00 70.69  ? 572 ALA A N   1 
ATOM   6216 C CA  . ALA B  1 572 ? 194.547 155.464 183.121 1.00 72.71  ? 572 ALA A CA  1 
ATOM   6217 C C   . ALA B  1 572 ? 195.887 156.190 183.070 1.00 77.97  ? 572 ALA A C   1 
ATOM   6218 O O   . ALA B  1 572 ? 196.432 156.411 181.984 1.00 82.47  ? 572 ALA A O   1 
ATOM   6219 C CB  . ALA B  1 572 ? 193.403 156.460 183.306 1.00 73.16  ? 572 ALA A CB  1 
ATOM   6220 N N   . TRP B  1 573 ? 196.434 156.565 184.235 1.00 76.66  ? 573 TRP A N   1 
ATOM   6221 C CA  . TRP B  1 573 ? 197.641 157.394 184.272 1.00 76.40  ? 573 TRP A CA  1 
ATOM   6222 C C   . TRP B  1 573 ? 198.817 156.707 183.590 1.00 77.62  ? 573 TRP A C   1 
ATOM   6223 O O   . TRP B  1 573 ? 199.542 157.331 182.797 1.00 76.56  ? 573 TRP A O   1 
ATOM   6224 C CB  . TRP B  1 573 ? 197.981 157.757 185.723 1.00 75.14  ? 573 TRP A CB  1 
ATOM   6225 C CG  . TRP B  1 573 ? 198.824 156.741 186.461 1.00 80.10  ? 573 TRP A CG  1 
ATOM   6226 C CD1 . TRP B  1 573 ? 198.393 155.559 186.983 1.00 79.36  ? 573 TRP A CD1 1 
ATOM   6227 C CD2 . TRP B  1 573 ? 200.223 156.828 186.778 1.00 79.08  ? 573 TRP A CD2 1 
ATOM   6228 N NE1 . TRP B  1 573 ? 199.431 154.897 187.591 1.00 77.09  ? 573 TRP A NE1 1 
ATOM   6229 C CE2 . TRP B  1 573 ? 200.566 155.656 187.481 1.00 77.18  ? 573 TRP A CE2 1 
ATOM   6230 C CE3 . TRP B  1 573 ? 201.218 157.777 186.533 1.00 74.13  ? 573 TRP A CE3 1 
ATOM   6231 C CZ2 . TRP B  1 573 ? 201.858 155.410 187.939 1.00 73.08  ? 573 TRP A CZ2 1 
ATOM   6232 C CZ3 . TRP B  1 573 ? 202.500 157.532 186.987 1.00 73.42  ? 573 TRP A CZ3 1 
ATOM   6233 C CH2 . TRP B  1 573 ? 202.808 156.358 187.683 1.00 72.31  ? 573 TRP A CH2 1 
ATOM   6234 N N   . THR B  1 574 ? 199.017 155.420 183.878 1.00 79.35  ? 574 THR A N   1 
ATOM   6235 C CA  . THR B  1 574 ? 200.055 154.653 183.206 1.00 83.63  ? 574 THR A CA  1 
ATOM   6236 C C   . THR B  1 574 ? 199.856 154.699 181.699 1.00 85.86  ? 574 THR A C   1 
ATOM   6237 O O   . THR B  1 574 ? 200.654 155.309 180.980 1.00 79.57  ? 574 THR A O   1 
ATOM   6238 C CB  . THR B  1 574 ? 200.038 153.212 183.711 1.00 79.69  ? 574 THR A CB  1 
ATOM   6239 O OG1 . THR B  1 574 ? 198.679 152.786 183.865 1.00 77.32  ? 574 THR A OG1 1 
ATOM   6240 C CG2 . THR B  1 574 ? 200.758 153.105 185.046 1.00 79.78  ? 574 THR A CG2 1 
ATOM   6241 N N   . ILE B  1 575 ? 198.736 154.133 181.235 1.00 90.48  ? 575 ILE A N   1 
ATOM   6242 C CA  . ILE B  1 575 ? 198.399 154.067 179.813 1.00 87.52  ? 575 ILE A CA  1 
ATOM   6243 C C   . ILE B  1 575 ? 198.646 155.402 179.125 1.00 87.40  ? 575 ILE A C   1 
ATOM   6244 O O   . ILE B  1 575 ? 199.156 155.451 177.998 1.00 87.96  ? 575 ILE A O   1 
ATOM   6245 C CB  . ILE B  1 575 ? 196.934 153.615 179.645 1.00 84.84  ? 575 ILE A CB  1 
ATOM   6246 C CG1 . ILE B  1 575 ? 196.842 152.092 179.581 1.00 86.76  ? 575 ILE A CG1 1 
ATOM   6247 C CG2 . ILE B  1 575 ? 196.305 154.233 178.404 1.00 83.99  ? 575 ILE A CG2 1 
ATOM   6248 C CD1 . ILE B  1 575 ? 195.420 151.569 179.538 1.00 86.16  ? 575 ILE A CD1 1 
ATOM   6249 N N   . GLN B  1 576 ? 198.315 156.504 179.794 1.00 84.68  ? 576 GLN A N   1 
ATOM   6250 C CA  . GLN B  1 576 ? 198.319 157.781 179.097 1.00 87.65  ? 576 GLN A CA  1 
ATOM   6251 C C   . GLN B  1 576 ? 199.701 158.425 179.052 1.00 86.99  ? 576 GLN A C   1 
ATOM   6252 O O   . GLN B  1 576 ? 200.147 158.832 177.974 1.00 89.64  ? 576 GLN A O   1 
ATOM   6253 C CB  . GLN B  1 576 ? 197.298 158.738 179.720 1.00 86.63  ? 576 GLN A CB  1 
ATOM   6254 C CG  . GLN B  1 576 ? 197.531 159.103 181.167 1.00 86.19  ? 576 GLN A CG  1 
ATOM   6255 C CD  . GLN B  1 576 ? 198.158 160.469 181.323 1.00 86.43  ? 576 GLN A CD  1 
ATOM   6256 O OE1 . GLN B  1 576 ? 198.141 161.282 180.400 1.00 84.40  ? 576 GLN A OE1 1 
ATOM   6257 N NE2 . GLN B  1 576 ? 198.696 160.739 182.503 1.00 86.17  ? 576 GLN A NE2 1 
ATOM   6258 N N   . ILE B  1 577 ? 200.406 158.539 180.181 1.00 84.31  ? 577 ILE A N   1 
ATOM   6259 C CA  . ILE B  1 577 ? 201.660 159.276 180.175 1.00 88.10  ? 577 ILE A CA  1 
ATOM   6260 C C   . ILE B  1 577 ? 202.860 158.436 180.605 1.00 84.66  ? 577 ILE A C   1 
ATOM   6261 O O   . ILE B  1 577 ? 203.991 158.782 180.246 1.00 81.77  ? 577 ILE A O   1 
ATOM   6262 C CB  . ILE B  1 577 ? 201.581 160.570 181.010 1.00 85.04  ? 577 ILE A CB  1 
ATOM   6263 C CG1 . ILE B  1 577 ? 202.490 161.628 180.389 1.00 82.98  ? 577 ILE A CG1 1 
ATOM   6264 C CG2 . ILE B  1 577 ? 202.054 160.328 182.419 1.00 80.29  ? 577 ILE A CG2 1 
ATOM   6265 C CD1 . ILE B  1 577 ? 201.936 162.244 179.130 1.00 84.16  ? 577 ILE A CD1 1 
ATOM   6266 N N   . SER B  1 578 ? 202.669 157.362 181.377 1.00 88.67  ? 578 SER A N   1 
ATOM   6267 C CA  . SER B  1 578 ? 203.809 156.493 181.618 1.00 87.91  ? 578 SER A CA  1 
ATOM   6268 C C   . SER B  1 578 ? 204.220 155.804 180.330 1.00 93.48  ? 578 SER A C   1 
ATOM   6269 O O   . SER B  1 578 ? 205.400 155.486 180.148 1.00 96.19  ? 578 SER A O   1 
ATOM   6270 C CB  . SER B  1 578 ? 203.490 155.465 182.705 1.00 90.17  ? 578 SER A CB  1 
ATOM   6271 O OG  . SER B  1 578 ? 203.378 156.077 183.980 1.00 91.70  ? 578 SER A OG  1 
ATOM   6272 N N   . ILE B  1 579 ? 203.264 155.615 179.422 1.00 97.27  ? 579 ILE A N   1 
ATOM   6273 C CA  . ILE B  1 579 ? 203.488 155.114 178.074 1.00 93.28  ? 579 ILE A CA  1 
ATOM   6274 C C   . ILE B  1 579 ? 202.825 156.105 177.126 1.00 92.25  ? 579 ILE A C   1 
ATOM   6275 O O   . ILE B  1 579 ? 202.378 157.173 177.559 1.00 93.66  ? 579 ILE A O   1 
ATOM   6276 C CB  . ILE B  1 579 ? 202.917 153.698 177.904 1.00 93.94  ? 579 ILE A CB  1 
ATOM   6277 C CG1 . ILE B  1 579 ? 203.098 152.911 179.197 1.00 91.42  ? 579 ILE A CG1 1 
ATOM   6278 C CG2 . ILE B  1 579 ? 203.639 152.982 176.796 1.00 95.66  ? 579 ILE A CG2 1 
ATOM   6279 C CD1 . ILE B  1 579 ? 204.534 152.611 179.503 1.00 90.54  ? 579 ILE A CD1 1 
ATOM   6280 N N   . THR B  1 580 ? 202.811 155.790 175.827 1.00 98.85  ? 580 THR A N   1 
ATOM   6281 C CA  . THR B  1 580 ? 202.081 156.555 174.817 1.00 103.68 ? 580 THR A CA  1 
ATOM   6282 C C   . THR B  1 580 ? 202.758 157.899 174.573 1.00 102.50 ? 580 THR A C   1 
ATOM   6283 O O   . THR B  1 580 ? 202.376 158.648 173.667 1.00 100.07 ? 580 THR A O   1 
ATOM   6284 C CB  . THR B  1 580 ? 200.614 156.747 175.230 1.00 101.39 ? 580 THR A CB  1 
ATOM   6285 O OG1 . THR B  1 580 ? 200.158 155.586 175.935 1.00 101.97 ? 580 THR A OG1 1 
ATOM   6286 C CG2 . THR B  1 580 ? 199.732 156.957 174.019 1.00 98.23  ? 580 THR A CG2 1 
ATOM   6287 N N   . SER B  1 581 ? 203.778 158.201 175.372 1.00 99.96  ? 581 SER A N   1 
ATOM   6288 C CA  . SER B  1 581 ? 204.584 159.397 175.208 1.00 98.68  ? 581 SER A CA  1 
ATOM   6289 C C   . SER B  1 581 ? 206.066 159.071 175.104 1.00 98.56  ? 581 SER A C   1 
ATOM   6290 O O   . SER B  1 581 ? 206.865 159.960 174.785 1.00 96.79  ? 581 SER A O   1 
ATOM   6291 C CB  . SER B  1 581 ? 204.333 160.367 176.368 1.00 96.62  ? 581 SER A CB  1 
ATOM   6292 O OG  . SER B  1 581 ? 202.973 160.349 176.761 1.00 95.14  ? 581 SER A OG  1 
ATOM   6293 N N   . THR B  1 582 ? 206.451 157.825 175.377 1.00 100.61 ? 582 THR A N   1 
ATOM   6294 C CA  . THR B  1 582 ? 207.756 157.299 175.018 1.00 99.68  ? 582 THR A CA  1 
ATOM   6295 C C   . THR B  1 582 ? 207.684 156.274 173.897 1.00 102.50 ? 582 THR A C   1 
ATOM   6296 O O   . THR B  1 582 ? 208.735 155.849 173.404 1.00 101.56 ? 582 THR A O   1 
ATOM   6297 C CB  . THR B  1 582 ? 208.440 156.664 176.237 1.00 98.38  ? 582 THR A CB  1 
ATOM   6298 O OG1 . THR B  1 582 ? 209.616 155.962 175.816 1.00 100.46 ? 582 THR A OG1 1 
ATOM   6299 C CG2 . THR B  1 582 ? 207.495 155.701 176.932 1.00 97.36  ? 582 THR A CG2 1 
ATOM   6300 N N   . THR B  1 583 ? 206.483 155.853 173.500 1.00 118.36 ? 583 THR A N   1 
ATOM   6301 C CA  . THR B  1 583 ? 206.270 155.019 172.326 1.00 118.73 ? 583 THR A CA  1 
ATOM   6302 C C   . THR B  1 583 ? 205.082 155.569 171.551 1.00 119.34 ? 583 THR A C   1 
ATOM   6303 O O   . THR B  1 583 ? 204.125 156.074 172.144 1.00 119.43 ? 583 THR A O   1 
ATOM   6304 C CB  . THR B  1 583 ? 206.013 153.552 172.695 1.00 117.32 ? 583 THR A CB  1 
ATOM   6305 O OG1 . THR B  1 583 ? 205.752 152.800 171.504 1.00 118.79 ? 583 THR A OG1 1 
ATOM   6306 C CG2 . THR B  1 583 ? 204.819 153.438 173.605 1.00 114.31 ? 583 THR A CG2 1 
ATOM   6307 N N   . LEU B  1 584 ? 205.153 155.488 170.225 1.00 128.12 ? 584 LEU A N   1 
ATOM   6308 C CA  . LEU B  1 584 ? 204.063 155.961 169.374 1.00 129.06 ? 584 LEU A CA  1 
ATOM   6309 C C   . LEU B  1 584 ? 203.240 154.770 168.882 1.00 127.96 ? 584 LEU A C   1 
ATOM   6310 O O   . LEU B  1 584 ? 203.307 154.354 167.725 1.00 126.04 ? 584 LEU A O   1 
ATOM   6311 C CB  . LEU B  1 584 ? 204.617 156.787 168.216 1.00 127.66 ? 584 LEU A CB  1 
ATOM   6312 C CG  . LEU B  1 584 ? 203.601 157.474 167.300 1.00 127.94 ? 584 LEU A CG  1 
ATOM   6313 C CD1 . LEU B  1 584 ? 202.633 158.323 168.110 1.00 127.01 ? 584 LEU A CD1 1 
ATOM   6314 C CD2 . LEU B  1 584 ? 204.307 158.315 166.250 1.00 127.59 ? 584 LEU A CD2 1 
ATOM   6315 N N   . LEU B  1 585 ? 202.456 154.209 169.802 1.00 124.02 ? 585 LEU A N   1 
ATOM   6316 C CA  . LEU B  1 585 ? 201.548 153.136 169.416 1.00 123.81 ? 585 LEU A CA  1 
ATOM   6317 C C   . LEU B  1 585 ? 200.300 153.716 168.749 1.00 123.18 ? 585 LEU A C   1 
ATOM   6318 O O   . LEU B  1 585 ? 199.994 153.342 167.609 1.00 122.66 ? 585 LEU A O   1 
ATOM   6319 C CB  . LEU B  1 585 ? 201.195 152.258 170.625 1.00 123.43 ? 585 LEU A CB  1 
ATOM   6320 C CG  . LEU B  1 585 ? 200.202 151.100 170.468 1.00 123.41 ? 585 LEU A CG  1 
ATOM   6321 C CD1 . LEU B  1 585 ? 200.575 149.964 171.405 1.00 121.15 ? 585 LEU A CD1 1 
ATOM   6322 C CD2 . LEU B  1 585 ? 198.769 151.543 170.736 1.00 123.03 ? 585 LEU A CD2 1 
ATOM   6323 N N   . PRO B  1 586 ? 199.542 154.630 169.405 1.00 120.59 ? 586 PRO A N   1 
ATOM   6324 C CA  . PRO B  1 586 ? 198.364 155.196 168.736 1.00 121.67 ? 586 PRO A CA  1 
ATOM   6325 C C   . PRO B  1 586 ? 198.631 156.546 168.087 1.00 122.21 ? 586 PRO A C   1 
ATOM   6326 O O   . PRO B  1 586 ? 199.507 157.297 168.529 1.00 121.14 ? 586 PRO A O   1 
ATOM   6327 C CB  . PRO B  1 586 ? 197.351 155.314 169.880 1.00 120.63 ? 586 PRO A CB  1 
ATOM   6328 C CG  . PRO B  1 586 ? 198.201 155.507 171.117 1.00 120.99 ? 586 PRO A CG  1 
ATOM   6329 C CD  . PRO B  1 586 ? 199.635 155.137 170.787 1.00 119.66 ? 586 PRO A CD  1 
ATOM   6330 N N   . HIS B  1 587 ? 197.878 156.865 167.031 1.00 116.23 ? 587 HIS A N   1 
ATOM   6331 C CA  . HIS B  1 587 ? 197.930 158.213 166.474 1.00 115.59 ? 587 HIS A CA  1 
ATOM   6332 C C   . HIS B  1 587 ? 197.319 159.226 167.434 1.00 111.26 ? 587 HIS A C   1 
ATOM   6333 O O   . HIS B  1 587 ? 197.825 160.346 167.572 1.00 110.12 ? 587 HIS A O   1 
ATOM   6334 C CB  . HIS B  1 587 ? 197.216 158.254 165.123 1.00 114.77 ? 587 HIS A CB  1 
ATOM   6335 C CG  . HIS B  1 587 ? 197.381 159.551 164.392 1.00 113.41 ? 587 HIS A CG  1 
ATOM   6336 N ND1 . HIS B  1 587 ? 198.342 160.479 164.730 1.00 114.41 ? 587 HIS A ND1 1 
ATOM   6337 C CD2 . HIS B  1 587 ? 196.704 160.075 163.344 1.00 112.12 ? 587 HIS A CD2 1 
ATOM   6338 C CE1 . HIS B  1 587 ? 198.251 161.519 163.920 1.00 113.72 ? 587 HIS A CE1 1 
ATOM   6339 N NE2 . HIS B  1 587 ? 197.265 161.299 163.069 1.00 112.83 ? 587 HIS A NE2 1 
ATOM   6340 N N   . SER B  1 588 ? 196.232 158.851 168.108 1.00 95.09  ? 588 SER A N   1 
ATOM   6341 C CA  . SER B  1 588 ? 195.543 159.701 169.077 1.00 96.99  ? 588 SER A CA  1 
ATOM   6342 C C   . SER B  1 588 ? 196.228 159.740 170.425 1.00 95.74  ? 588 SER A C   1 
ATOM   6343 O O   . SER B  1 588 ? 195.619 160.218 171.400 1.00 96.59  ? 588 SER A O   1 
ATOM   6344 C CB  . SER B  1 588 ? 194.098 159.232 169.248 1.00 98.54  ? 588 SER A CB  1 
ATOM   6345 O OG  . SER B  1 588 ? 193.956 158.452 170.421 1.00 98.89  ? 588 SER A OG  1 
ATOM   6346 N N   . GLY B  1 589 ? 197.465 159.246 170.495 1.00 95.47  ? 589 GLY A N   1 
ATOM   6347 C CA  . GLY B  1 589 ? 198.185 159.245 171.754 1.00 99.76  ? 589 GLY A CA  1 
ATOM   6348 C C   . GLY B  1 589 ? 198.372 160.632 172.332 1.00 101.79 ? 589 GLY A C   1 
ATOM   6349 O O   . GLY B  1 589 ? 198.309 160.812 173.551 1.00 103.72 ? 589 GLY A O   1 
ATOM   6350 N N   . ASP B  1 590 ? 198.606 161.626 171.475 1.00 93.33  ? 590 ASP A N   1 
ATOM   6351 C CA  . ASP B  1 590 ? 198.732 162.998 171.952 1.00 90.35  ? 590 ASP A CA  1 
ATOM   6352 C C   . ASP B  1 590 ? 197.440 163.467 172.608 1.00 88.02  ? 590 ASP A C   1 
ATOM   6353 O O   . ASP B  1 590 ? 197.463 164.077 173.682 1.00 90.67  ? 590 ASP A O   1 
ATOM   6354 C CB  . ASP B  1 590 ? 199.117 163.921 170.797 1.00 89.96  ? 590 ASP A CB  1 
ATOM   6355 C CG  . ASP B  1 590 ? 200.313 163.415 170.024 1.00 96.17  ? 590 ASP A CG  1 
ATOM   6356 O OD1 . ASP B  1 590 ? 200.145 163.042 168.845 1.00 100.90 ? 590 ASP A OD1 1 
ATOM   6357 O OD2 . ASP B  1 590 ? 201.423 163.389 170.597 1.00 94.25  ? 590 ASP A OD2 1 
ATOM   6358 N N   . ILE B  1 591 ? 196.298 163.177 171.979 1.00 77.84  ? 591 ILE A N   1 
ATOM   6359 C CA  . ILE B  1 591 ? 195.013 163.564 172.557 1.00 79.75  ? 591 ILE A CA  1 
ATOM   6360 C C   . ILE B  1 591 ? 194.800 162.869 173.892 1.00 80.78  ? 591 ILE A C   1 
ATOM   6361 O O   . ILE B  1 591 ? 194.378 163.494 174.872 1.00 76.41  ? 591 ILE A O   1 
ATOM   6362 C CB  . ILE B  1 591 ? 193.862 163.262 171.580 1.00 78.78  ? 591 ILE A CB  1 
ATOM   6363 C CG1 . ILE B  1 591 ? 194.076 163.982 170.249 1.00 81.42  ? 591 ILE A CG1 1 
ATOM   6364 C CG2 . ILE B  1 591 ? 192.532 163.665 172.190 1.00 75.52  ? 591 ILE A CG2 1 
ATOM   6365 C CD1 . ILE B  1 591 ? 194.136 163.059 169.057 1.00 80.72  ? 591 ILE A CD1 1 
ATOM   6366 N N   . ILE B  1 592 ? 195.090 161.567 173.955 1.00 83.52  ? 592 ILE A N   1 
ATOM   6367 C CA  . ILE B  1 592 ? 194.867 160.818 175.190 1.00 81.21  ? 592 ILE A CA  1 
ATOM   6368 C C   . ILE B  1 592 ? 195.743 161.364 176.311 1.00 80.33  ? 592 ILE A C   1 
ATOM   6369 O O   . ILE B  1 592 ? 195.276 161.596 177.433 1.00 84.79  ? 592 ILE A O   1 
ATOM   6370 C CB  . ILE B  1 592 ? 195.112 159.316 174.963 1.00 79.78  ? 592 ILE A CB  1 
ATOM   6371 C CG1 . ILE B  1 592 ? 194.211 158.790 173.844 1.00 80.01  ? 592 ILE A CG1 1 
ATOM   6372 C CG2 . ILE B  1 592 ? 194.868 158.538 176.245 1.00 81.59  ? 592 ILE A CG2 1 
ATOM   6373 C CD1 . ILE B  1 592 ? 192.740 159.051 174.072 1.00 80.71  ? 592 ILE A CD1 1 
ATOM   6374 N N   . ALA B  1 593 ? 197.027 161.587 176.022 1.00 71.82  ? 593 ALA A N   1 
ATOM   6375 C CA  . ALA B  1 593 ? 197.936 162.093 177.045 1.00 74.71  ? 593 ALA A CA  1 
ATOM   6376 C C   . ALA B  1 593 ? 197.534 163.490 177.500 1.00 77.13  ? 593 ALA A C   1 
ATOM   6377 O O   . ALA B  1 593 ? 197.518 163.776 178.704 1.00 80.04  ? 593 ALA A O   1 
ATOM   6378 C CB  . ALA B  1 593 ? 199.369 162.091 176.517 1.00 71.74  ? 593 ALA A CB  1 
ATOM   6379 N N   . THR B  1 594 ? 197.195 164.370 176.555 1.00 67.14  ? 594 THR A N   1 
ATOM   6380 C CA  . THR B  1 594 ? 196.826 165.735 176.909 1.00 63.24  ? 594 THR A CA  1 
ATOM   6381 C C   . THR B  1 594 ? 195.537 165.771 177.716 1.00 69.29  ? 594 THR A C   1 
ATOM   6382 O O   . THR B  1 594 ? 195.385 166.608 178.612 1.00 76.52  ? 594 THR A O   1 
ATOM   6383 C CB  . THR B  1 594 ? 196.684 166.587 175.650 1.00 68.46  ? 594 THR A CB  1 
ATOM   6384 O OG1 . THR B  1 594 ? 197.699 166.224 174.707 1.00 70.87  ? 594 THR A OG1 1 
ATOM   6385 C CG2 . THR B  1 594 ? 196.818 168.058 175.992 1.00 71.20  ? 594 THR A CG2 1 
ATOM   6386 N N   . VAL B  1 595 ? 194.594 164.877 177.414 1.00 66.00  ? 595 VAL A N   1 
ATOM   6387 C CA  . VAL B  1 595 ? 193.328 164.894 178.132 1.00 66.13  ? 595 VAL A CA  1 
ATOM   6388 C C   . VAL B  1 595 ? 193.417 164.165 179.464 1.00 66.10  ? 595 VAL A C   1 
ATOM   6389 O O   . VAL B  1 595 ? 192.596 164.421 180.349 1.00 62.95  ? 595 VAL A O   1 
ATOM   6390 C CB  . VAL B  1 595 ? 192.202 164.294 177.271 1.00 66.89  ? 595 VAL A CB  1 
ATOM   6391 C CG1 . VAL B  1 595 ? 192.290 162.778 177.239 1.00 68.92  ? 595 VAL A CG1 1 
ATOM   6392 C CG2 . VAL B  1 595 ? 190.840 164.747 177.774 1.00 67.03  ? 595 VAL A CG2 1 
ATOM   6393 N N   . PHE B  1 596 ? 194.401 163.281 179.650 1.00 73.71  ? 596 PHE A N   1 
ATOM   6394 C CA  . PHE B  1 596 ? 194.473 162.492 180.872 1.00 71.20  ? 596 PHE A CA  1 
ATOM   6395 C C   . PHE B  1 596 ? 195.508 162.983 181.875 1.00 70.27  ? 596 PHE A C   1 
ATOM   6396 O O   . PHE B  1 596 ? 195.404 162.634 183.056 1.00 72.47  ? 596 PHE A O   1 
ATOM   6397 C CB  . PHE B  1 596 ? 194.766 161.027 180.539 1.00 65.06  ? 596 PHE A CB  1 
ATOM   6398 C CG  . PHE B  1 596 ? 193.563 160.135 180.603 1.00 72.31  ? 596 PHE A CG  1 
ATOM   6399 C CD1 . PHE B  1 596 ? 192.687 160.207 181.673 1.00 75.44  ? 596 PHE A CD1 1 
ATOM   6400 C CD2 . PHE B  1 596 ? 193.317 159.211 179.603 1.00 75.07  ? 596 PHE A CD2 1 
ATOM   6401 C CE1 . PHE B  1 596 ? 191.580 159.385 181.737 1.00 71.26  ? 596 PHE A CE1 1 
ATOM   6402 C CE2 . PHE B  1 596 ? 192.213 158.386 179.663 1.00 78.31  ? 596 PHE A CE2 1 
ATOM   6403 C CZ  . PHE B  1 596 ? 191.343 158.473 180.731 1.00 72.90  ? 596 PHE A CZ  1 
ATOM   6404 N N   . ALA B  1 597 ? 196.507 163.758 181.449 1.00 63.15  ? 597 ALA A N   1 
ATOM   6405 C CA  . ALA B  1 597 ? 197.442 164.331 182.415 1.00 64.12  ? 597 ALA A CA  1 
ATOM   6406 C C   . ALA B  1 597 ? 196.755 165.203 183.464 1.00 66.66  ? 597 ALA A C   1 
ATOM   6407 O O   . ALA B  1 597 ? 197.143 165.119 184.645 1.00 69.06  ? 597 ALA A O   1 
ATOM   6408 C CB  . ALA B  1 597 ? 198.540 165.107 181.676 1.00 61.88  ? 597 ALA A CB  1 
ATOM   6409 N N   . PRO B  1 598 ? 195.777 166.053 183.128 1.00 55.03  ? 598 PRO A N   1 
ATOM   6410 C CA  . PRO B  1 598 ? 195.012 166.716 184.194 1.00 52.33  ? 598 PRO A CA  1 
ATOM   6411 C C   . PRO B  1 598 ? 194.358 165.745 185.160 1.00 58.91  ? 598 PRO A C   1 
ATOM   6412 O O   . PRO B  1 598 ? 194.329 166.022 186.363 1.00 63.89  ? 598 PRO A O   1 
ATOM   6413 C CB  . PRO B  1 598 ? 193.974 167.534 183.418 1.00 58.96  ? 598 PRO A CB  1 
ATOM   6414 C CG  . PRO B  1 598 ? 194.635 167.825 182.133 1.00 59.91  ? 598 PRO A CG  1 
ATOM   6415 C CD  . PRO B  1 598 ? 195.434 166.602 181.804 1.00 56.83  ? 598 PRO A CD  1 
ATOM   6416 N N   . LEU B  1 599 ? 193.840 164.608 184.686 1.00 59.20  ? 599 LEU A N   1 
ATOM   6417 C CA  . LEU B  1 599 ? 193.333 163.616 185.629 1.00 59.54  ? 599 LEU A CA  1 
ATOM   6418 C C   . LEU B  1 599 ? 194.454 162.971 186.431 1.00 58.36  ? 599 LEU A C   1 
ATOM   6419 O O   . LEU B  1 599 ? 194.220 162.528 187.556 1.00 61.12  ? 599 LEU A O   1 
ATOM   6420 C CB  . LEU B  1 599 ? 192.504 162.544 184.923 1.00 55.68  ? 599 LEU A CB  1 
ATOM   6421 C CG  . LEU B  1 599 ? 191.174 162.962 184.292 1.00 59.44  ? 599 LEU A CG  1 
ATOM   6422 C CD1 . LEU B  1 599 ? 190.488 164.027 185.136 1.00 61.14  ? 599 LEU A CD1 1 
ATOM   6423 C CD2 . LEU B  1 599 ? 191.345 163.429 182.875 1.00 59.17  ? 599 LEU A CD2 1 
ATOM   6424 N N   . GLU B  1 600 ? 195.669 162.912 185.888 1.00 58.54  ? 600 GLU A N   1 
ATOM   6425 C CA  . GLU B  1 600 ? 196.801 162.461 186.692 1.00 54.97  ? 600 GLU A CA  1 
ATOM   6426 C C   . GLU B  1 600 ? 197.034 163.398 187.868 1.00 64.65  ? 600 GLU A C   1 
ATOM   6427 O O   . GLU B  1 600 ? 197.185 162.959 189.016 1.00 66.38  ? 600 GLU A O   1 
ATOM   6428 C CB  . GLU B  1 600 ? 198.057 162.379 185.834 1.00 56.34  ? 600 GLU A CB  1 
ATOM   6429 C CG  . GLU B  1 600 ? 199.017 161.302 186.251 1.00 62.41  ? 600 GLU A CG  1 
ATOM   6430 C CD  . GLU B  1 600 ? 200.058 161.050 185.195 1.00 71.42  ? 600 GLU A CD  1 
ATOM   6431 O OE1 . GLU B  1 600 ? 200.248 159.880 184.822 1.00 68.17  ? 600 GLU A OE1 1 
ATOM   6432 O OE2 . GLU B  1 600 ? 200.692 162.026 184.741 1.00 72.17  ? 600 GLU A OE2 1 
ATOM   6433 N N   . VAL B  1 601 ? 197.063 164.704 187.596 1.00 57.77  ? 601 VAL A N   1 
ATOM   6434 C CA  . VAL B  1 601 ? 197.254 165.661 188.680 1.00 44.90  ? 601 VAL A CA  1 
ATOM   6435 C C   . VAL B  1 601 ? 196.061 165.651 189.628 1.00 52.33  ? 601 VAL A C   1 
ATOM   6436 O O   . VAL B  1 601 ? 196.219 165.868 190.830 1.00 53.99  ? 601 VAL A O   1 
ATOM   6437 C CB  . VAL B  1 601 ? 197.526 167.067 188.119 1.00 36.19  ? 601 VAL A CB  1 
ATOM   6438 C CG1 . VAL B  1 601 ? 197.880 168.017 189.241 1.00 41.91  ? 601 VAL A CG1 1 
ATOM   6439 C CG2 . VAL B  1 601 ? 198.654 167.009 187.114 1.00 45.70  ? 601 VAL A CG2 1 
ATOM   6440 N N   . PHE B  1 602 ? 194.857 165.390 189.116 1.00 46.20  ? 602 PHE A N   1 
ATOM   6441 C CA  . PHE B  1 602 ? 193.689 165.279 189.986 1.00 36.41  ? 602 PHE A CA  1 
ATOM   6442 C C   . PHE B  1 602 ? 193.785 164.061 190.899 1.00 45.49  ? 602 PHE A C   1 
ATOM   6443 O O   . PHE B  1 602 ? 193.420 164.129 192.080 1.00 59.49  ? 602 PHE A O   1 
ATOM   6444 C CB  . PHE B  1 602 ? 192.416 165.221 189.144 1.00 35.63  ? 602 PHE A CB  1 
ATOM   6445 C CG  . PHE B  1 602 ? 191.168 165.025 189.949 1.00 47.38  ? 602 PHE A CG  1 
ATOM   6446 C CD1 . PHE B  1 602 ? 190.582 166.089 190.609 1.00 51.51  ? 602 PHE A CD1 1 
ATOM   6447 C CD2 . PHE B  1 602 ? 190.577 163.779 190.042 1.00 48.77  ? 602 PHE A CD2 1 
ATOM   6448 C CE1 . PHE B  1 602 ? 189.434 165.912 191.351 1.00 53.37  ? 602 PHE A CE1 1 
ATOM   6449 C CE2 . PHE B  1 602 ? 189.429 163.596 190.782 1.00 47.98  ? 602 PHE A CE2 1 
ATOM   6450 C CZ  . PHE B  1 602 ? 188.857 164.664 191.437 1.00 51.63  ? 602 PHE A CZ  1 
ATOM   6451 N N   . ARG B  1 603 ? 194.254 162.932 190.364 1.00 40.63  ? 603 ARG A N   1 
ATOM   6452 C CA  . ARG B  1 603 ? 194.456 161.747 191.189 1.00 42.65  ? 603 ARG A CA  1 
ATOM   6453 C C   . ARG B  1 603 ? 195.501 162.009 192.256 1.00 42.98  ? 603 ARG A C   1 
ATOM   6454 O O   . ARG B  1 603 ? 195.356 161.573 193.402 1.00 48.79  ? 603 ARG A O   1 
ATOM   6455 C CB  . ARG B  1 603 ? 194.871 160.560 190.324 1.00 43.05  ? 603 ARG A CB  1 
ATOM   6456 C CG  . ARG B  1 603 ? 194.858 159.236 191.063 1.00 38.00  ? 603 ARG A CG  1 
ATOM   6457 C CD  . ARG B  1 603 ? 195.985 158.330 190.606 1.00 48.17  ? 603 ARG A CD  1 
ATOM   6458 N NE  . ARG B  1 603 ? 197.225 158.595 191.324 1.00 43.76  ? 603 ARG A NE  1 
ATOM   6459 C CZ  . ARG B  1 603 ? 198.381 158.876 190.741 1.00 48.20  ? 603 ARG A CZ  1 
ATOM   6460 N NH1 . ARG B  1 603 ? 198.494 158.942 189.425 1.00 45.52  ? 603 ARG A NH1 1 
ATOM   6461 N NH2 . ARG B  1 603 ? 199.452 159.095 191.497 1.00 51.93  ? 603 ARG A NH2 1 
ATOM   6462 N N   . ARG B  1 604 ? 196.566 162.722 191.899 1.00 39.90  ? 604 ARG A N   1 
ATOM   6463 C CA  . ARG B  1 604 ? 197.554 163.095 192.902 1.00 35.65  ? 604 ARG A CA  1 
ATOM   6464 C C   . ARG B  1 604 ? 196.955 164.033 193.944 1.00 42.22  ? 604 ARG A C   1 
ATOM   6465 O O   . ARG B  1 604 ? 197.269 163.935 195.135 1.00 46.06  ? 604 ARG A O   1 
ATOM   6466 C CB  . ARG B  1 604 ? 198.759 163.736 192.228 1.00 33.57  ? 604 ARG A CB  1 
ATOM   6467 C CG  . ARG B  1 604 ? 199.863 164.059 193.185 1.00 28.91  ? 604 ARG A CG  1 
ATOM   6468 C CD  . ARG B  1 604 ? 200.243 162.863 194.037 1.00 25.61  ? 604 ARG A CD  1 
ATOM   6469 N NE  . ARG B  1 604 ? 200.875 161.813 193.250 1.00 40.04  ? 604 ARG A NE  1 
ATOM   6470 C CZ  . ARG B  1 604 ? 201.519 160.775 193.763 1.00 39.38  ? 604 ARG A CZ  1 
ATOM   6471 N NH1 . ARG B  1 604 ? 201.649 160.620 195.069 1.00 30.09  ? 604 ARG A NH1 1 
ATOM   6472 N NH2 . ARG B  1 604 ? 202.047 159.871 192.945 1.00 39.69  ? 604 ARG A NH2 1 
ATOM   6473 N N   . PHE B  1 605 ? 196.084 164.945 193.511 1.00 34.31  ? 605 PHE A N   1 
ATOM   6474 C CA  . PHE B  1 605 ? 195.441 165.883 194.424 1.00 27.83  ? 605 PHE A CA  1 
ATOM   6475 C C   . PHE B  1 605 ? 194.580 165.153 195.446 1.00 35.17  ? 605 PHE A C   1 
ATOM   6476 O O   . PHE B  1 605 ? 194.612 165.469 196.640 1.00 45.72  ? 605 PHE A O   1 
ATOM   6477 C CB  . PHE B  1 605 ? 194.613 166.884 193.615 1.00 33.54  ? 605 PHE A CB  1 
ATOM   6478 C CG  . PHE B  1 605 ? 193.345 167.333 194.287 1.00 42.14  ? 605 PHE A CG  1 
ATOM   6479 C CD1 . PHE B  1 605 ? 193.379 168.162 195.392 1.00 41.15  ? 605 PHE A CD1 1 
ATOM   6480 C CD2 . PHE B  1 605 ? 192.114 166.939 193.794 1.00 37.90  ? 605 PHE A CD2 1 
ATOM   6481 C CE1 . PHE B  1 605 ? 192.212 168.577 195.995 1.00 33.87  ? 605 PHE A CE1 1 
ATOM   6482 C CE2 . PHE B  1 605 ? 190.947 167.351 194.397 1.00 28.07  ? 605 PHE A CE2 1 
ATOM   6483 C CZ  . PHE B  1 605 ? 190.996 168.170 195.498 1.00 28.31  ? 605 PHE A CZ  1 
ATOM   6484 N N   . VAL B  1 606 ? 193.800 164.171 194.993 1.00 37.81  ? 606 VAL A N   1 
ATOM   6485 C CA  . VAL B  1 606 ? 192.975 163.417 195.935 1.00 39.76  ? 606 VAL A CA  1 
ATOM   6486 C C   . VAL B  1 606 ? 193.833 162.488 196.790 1.00 48.85  ? 606 VAL A C   1 
ATOM   6487 O O   . VAL B  1 606 ? 193.536 162.278 197.972 1.00 56.61  ? 606 VAL A O   1 
ATOM   6488 C CB  . VAL B  1 606 ? 191.855 162.657 195.200 1.00 35.79  ? 606 VAL A CB  1 
ATOM   6489 C CG1 . VAL B  1 606 ? 192.426 161.671 194.226 1.00 44.50  ? 606 VAL A CG1 1 
ATOM   6490 C CG2 . VAL B  1 606 ? 190.955 161.949 196.195 1.00 36.56  ? 606 VAL A CG2 1 
ATOM   6491 N N   . TRP B  1 607 ? 194.909 161.927 196.227 1.00 44.26  ? 607 TRP A N   1 
ATOM   6492 C CA  . TRP B  1 607 ? 195.815 161.097 197.013 1.00 30.66  ? 607 TRP A CA  1 
ATOM   6493 C C   . TRP B  1 607 ? 196.478 161.896 198.122 1.00 33.50  ? 607 TRP A C   1 
ATOM   6494 O O   . TRP B  1 607 ? 196.772 161.349 199.190 1.00 42.58  ? 607 TRP A O   1 
ATOM   6495 C CB  . TRP B  1 607 ? 196.874 160.477 196.099 1.00 37.25  ? 607 TRP A CB  1 
ATOM   6496 C CG  . TRP B  1 607 ? 198.006 159.787 196.812 1.00 35.51  ? 607 TRP A CG  1 
ATOM   6497 C CD1 . TRP B  1 607 ? 198.109 158.457 197.082 1.00 37.00  ? 607 TRP A CD1 1 
ATOM   6498 C CD2 . TRP B  1 607 ? 199.205 160.391 197.318 1.00 34.08  ? 607 TRP A CD2 1 
ATOM   6499 N NE1 . TRP B  1 607 ? 199.286 158.194 197.735 1.00 33.88  ? 607 TRP A NE1 1 
ATOM   6500 C CE2 . TRP B  1 607 ? 199.977 159.366 197.891 1.00 28.92  ? 607 TRP A CE2 1 
ATOM   6501 C CE3 . TRP B  1 607 ? 199.695 161.698 197.348 1.00 44.31  ? 607 TRP A CE3 1 
ATOM   6502 C CZ2 . TRP B  1 607 ? 201.211 159.607 198.486 1.00 30.60  ? 607 TRP A CZ2 1 
ATOM   6503 C CZ3 . TRP B  1 607 ? 200.920 161.934 197.938 1.00 37.36  ? 607 TRP A CZ3 1 
ATOM   6504 C CH2 . TRP B  1 607 ? 201.663 160.895 198.499 1.00 32.56  ? 607 TRP A CH2 1 
ATOM   6505 N N   . ASN B  1 608 ? 196.737 163.182 197.876 1.00 27.07  ? 608 ASN A N   1 
ATOM   6506 C CA  . ASN B  1 608 ? 197.355 164.029 198.889 1.00 23.32  ? 608 ASN A CA  1 
ATOM   6507 C C   . ASN B  1 608 ? 196.491 164.105 200.137 1.00 34.16  ? 608 ASN A C   1 
ATOM   6508 O O   . ASN B  1 608 ? 196.999 164.003 201.261 1.00 42.07  ? 608 ASN A O   1 
ATOM   6509 C CB  . ASN B  1 608 ? 197.585 165.428 198.324 1.00 20.08  ? 608 ASN A CB  1 
ATOM   6510 C CG  . ASN B  1 608 ? 199.016 165.663 197.917 1.00 39.58  ? 608 ASN A CG  1 
ATOM   6511 O OD1 . ASN B  1 608 ? 199.946 165.307 198.638 1.00 43.08  ? 608 ASN A OD1 1 
ATOM   6512 N ND2 . ASN B  1 608 ? 199.203 166.267 196.751 1.00 49.08  ? 608 ASN A ND2 1 
ATOM   6513 N N   . PHE B  1 609 ? 195.178 164.266 199.952 1.00 33.54  ? 609 PHE A N   1 
ATOM   6514 C CA  . PHE B  1 609 ? 194.263 164.388 201.079 1.00 34.76  ? 609 PHE A CA  1 
ATOM   6515 C C   . PHE B  1 609 ? 194.413 163.213 202.028 1.00 46.00  ? 609 PHE A C   1 
ATOM   6516 O O   . PHE B  1 609 ? 194.676 163.385 203.224 1.00 59.42  ? 609 PHE A O   1 
ATOM   6517 C CB  . PHE B  1 609 ? 192.822 164.461 200.572 1.00 26.77  ? 609 PHE A CB  1 
ATOM   6518 C CG  . PHE B  1 609 ? 192.329 165.850 200.329 1.00 31.17  ? 609 PHE A CG  1 
ATOM   6519 C CD1 . PHE B  1 609 ? 192.524 166.841 201.268 1.00 41.84  ? 609 PHE A CD1 1 
ATOM   6520 C CD2 . PHE B  1 609 ? 191.651 166.158 199.168 1.00 33.75  ? 609 PHE A CD2 1 
ATOM   6521 C CE1 . PHE B  1 609 ? 192.066 168.118 201.046 1.00 46.67  ? 609 PHE A CE1 1 
ATOM   6522 C CE2 . PHE B  1 609 ? 191.189 167.430 198.943 1.00 32.63  ? 609 PHE A CE2 1 
ATOM   6523 C CZ  . PHE B  1 609 ? 191.398 168.413 199.883 1.00 36.47  ? 609 PHE A CZ  1 
ATOM   6524 N N   . PHE B  1 610 ? 194.307 162.000 201.494 1.00 40.75  ? 610 PHE A N   1 
ATOM   6525 C CA  . PHE B  1 610 ? 194.260 160.830 202.353 1.00 44.70  ? 610 PHE A CA  1 
ATOM   6526 C C   . PHE B  1 610 ? 195.642 160.379 202.798 1.00 43.65  ? 610 PHE A C   1 
ATOM   6527 O O   . PHE B  1 610 ? 195.769 159.824 203.890 1.00 49.74  ? 610 PHE A O   1 
ATOM   6528 C CB  . PHE B  1 610 ? 193.500 159.712 201.649 1.00 39.06  ? 610 PHE A CB  1 
ATOM   6529 C CG  . PHE B  1 610 ? 192.108 160.104 201.269 1.00 32.92  ? 610 PHE A CG  1 
ATOM   6530 C CD1 . PHE B  1 610 ? 191.115 160.172 202.226 1.00 33.12  ? 610 PHE A CD1 1 
ATOM   6531 C CD2 . PHE B  1 610 ? 191.802 160.454 199.969 1.00 44.29  ? 610 PHE A CD2 1 
ATOM   6532 C CE1 . PHE B  1 610 ? 189.837 160.550 201.888 1.00 45.29  ? 610 PHE A CE1 1 
ATOM   6533 C CE2 . PHE B  1 610 ? 190.527 160.836 199.627 1.00 40.50  ? 610 PHE A CE2 1 
ATOM   6534 C CZ  . PHE B  1 610 ? 189.542 160.883 200.586 1.00 44.77  ? 610 PHE A CZ  1 
ATOM   6535 N N   . ARG B  1 611 ? 196.693 160.641 202.019 1.00 32.42  ? 611 ARG A N   1 
ATOM   6536 C CA  . ARG B  1 611 ? 198.030 160.368 202.529 1.00 19.01  ? 611 ARG A CA  1 
ATOM   6537 C C   . ARG B  1 611 ? 198.346 161.268 203.717 1.00 31.39  ? 611 ARG A C   1 
ATOM   6538 O O   . ARG B  1 611 ? 198.841 160.796 204.746 1.00 55.35  ? 611 ARG A O   1 
ATOM   6539 C CB  . ARG B  1 611 ? 199.073 160.528 201.422 1.00 36.44  ? 611 ARG A CB  1 
ATOM   6540 C CG  . ARG B  1 611 ? 200.450 160.971 201.901 1.00 36.24  ? 611 ARG A CG  1 
ATOM   6541 C CD  . ARG B  1 611 ? 201.134 159.925 202.779 1.00 31.01  ? 611 ARG A CD  1 
ATOM   6542 N NE  . ARG B  1 611 ? 201.740 158.837 202.024 1.00 34.14  ? 611 ARG A NE  1 
ATOM   6543 C CZ  . ARG B  1 611 ? 202.545 157.926 202.553 1.00 45.31  ? 611 ARG A CZ  1 
ATOM   6544 N NH1 . ARG B  1 611 ? 202.858 157.945 203.837 1.00 49.59  ? 611 ARG A NH1 1 
ATOM   6545 N NH2 . ARG B  1 611 ? 203.050 156.975 201.774 1.00 49.09  ? 611 ARG A NH2 1 
ATOM   6546 N N   . LEU B  1 612 ? 198.046 162.565 203.610 1.00 35.22  ? 612 LEU A N   1 
ATOM   6547 C CA  . LEU B  1 612 ? 198.303 163.455 204.737 1.00 39.66  ? 612 LEU A CA  1 
ATOM   6548 C C   . LEU B  1 612 ? 197.411 163.113 205.924 1.00 53.12  ? 612 LEU A C   1 
ATOM   6549 O O   . LEU B  1 612 ? 197.853 163.176 207.079 1.00 54.90  ? 612 LEU A O   1 
ATOM   6550 C CB  . LEU B  1 612 ? 198.110 164.909 204.314 1.00 37.37  ? 612 LEU A CB  1 
ATOM   6551 C CG  . LEU B  1 612 ? 199.397 165.676 204.014 1.00 35.36  ? 612 LEU A CG  1 
ATOM   6552 C CD1 . LEU B  1 612 ? 200.280 165.735 205.242 1.00 36.81  ? 612 LEU A CD1 1 
ATOM   6553 C CD2 . LEU B  1 612 ? 200.135 165.038 202.854 1.00 41.41  ? 612 LEU A CD2 1 
ATOM   6554 N N   . GLU B  1 613 ? 196.156 162.739 205.661 1.00 54.49  ? 613 GLU A N   1 
ATOM   6555 C CA  . GLU B  1 613 ? 195.257 162.349 206.741 1.00 49.24  ? 613 GLU A CA  1 
ATOM   6556 C C   . GLU B  1 613 ? 195.744 161.087 207.444 1.00 52.36  ? 613 GLU A C   1 
ATOM   6557 O O   . GLU B  1 613 ? 195.650 160.980 208.672 1.00 60.84  ? 613 GLU A O   1 
ATOM   6558 C CB  . GLU B  1 613 ? 193.847 162.163 206.187 1.00 49.06  ? 613 GLU A CB  1 
ATOM   6559 C CG  . GLU B  1 613 ? 192.846 161.608 207.170 1.00 58.88  ? 613 GLU A CG  1 
ATOM   6560 C CD  . GLU B  1 613 ? 192.079 160.436 206.606 1.00 60.00  ? 613 GLU A CD  1 
ATOM   6561 O OE1 . GLU B  1 613 ? 192.449 159.948 205.519 1.00 58.66  ? 613 GLU A OE1 1 
ATOM   6562 O OE2 . GLU B  1 613 ? 191.103 159.999 207.248 1.00 64.33  ? 613 GLU A OE2 1 
ATOM   6563 N N   . ASN B  1 614 ? 196.267 160.122 206.685 1.00 47.32  ? 614 ASN A N   1 
ATOM   6564 C CA  . ASN B  1 614 ? 196.856 158.935 207.292 1.00 47.30  ? 614 ASN A CA  1 
ATOM   6565 C C   . ASN B  1 614 ? 198.098 159.292 208.094 1.00 41.71  ? 614 ASN A C   1 
ATOM   6566 O O   . ASN B  1 614 ? 198.338 158.727 209.164 1.00 53.61  ? 614 ASN A O   1 
ATOM   6567 C CB  . ASN B  1 614 ? 197.192 157.911 206.209 1.00 45.25  ? 614 ASN A CB  1 
ATOM   6568 C CG  . ASN B  1 614 ? 197.257 156.498 206.742 1.00 42.60  ? 614 ASN A CG  1 
ATOM   6569 O OD1 . ASN B  1 614 ? 197.887 155.626 206.149 1.00 41.25  ? 614 ASN A OD1 1 
ATOM   6570 N ND2 . ASN B  1 614 ? 196.597 156.263 207.869 1.00 50.33  ? 614 ASN A ND2 1 
ATOM   6571 N N   . GLU B  1 615 ? 198.898 160.234 207.590 1.00 40.26  ? 615 GLU A N   1 
ATOM   6572 C CA  . GLU B  1 615 ? 200.085 160.666 208.318 1.00 42.90  ? 615 GLU A CA  1 
ATOM   6573 C C   . GLU B  1 615 ? 199.715 161.280 209.660 1.00 56.87  ? 615 GLU A C   1 
ATOM   6574 O O   . GLU B  1 615 ? 200.374 161.021 210.674 1.00 64.25  ? 615 GLU A O   1 
ATOM   6575 C CB  . GLU B  1 615 ? 200.874 161.668 207.480 1.00 44.54  ? 615 GLU A CB  1 
ATOM   6576 C CG  . GLU B  1 615 ? 201.600 161.063 206.303 1.00 51.32  ? 615 GLU A CG  1 
ATOM   6577 C CD  . GLU B  1 615 ? 202.804 160.254 206.717 1.00 58.77  ? 615 GLU A CD  1 
ATOM   6578 O OE1 . GLU B  1 615 ? 203.766 160.847 207.246 1.00 56.38  ? 615 GLU A OE1 1 
ATOM   6579 O OE2 . GLU B  1 615 ? 202.791 159.026 206.504 1.00 58.85  ? 615 GLU A OE2 1 
ATOM   6580 N N   . HIS B  1 616 ? 198.670 162.108 209.685 1.00 51.36  ? 616 HIS A N   1 
ATOM   6581 C CA  . HIS B  1 616 ? 198.257 162.733 210.937 1.00 50.49  ? 616 HIS A CA  1 
ATOM   6582 C C   . HIS B  1 616 ? 197.725 161.706 211.927 1.00 56.51  ? 616 HIS A C   1 
ATOM   6583 O O   . HIS B  1 616 ? 198.072 161.737 213.113 1.00 60.77  ? 616 HIS A O   1 
ATOM   6584 C CB  . HIS B  1 616 ? 197.200 163.799 210.666 1.00 55.02  ? 616 HIS A CB  1 
ATOM   6585 C CG  . HIS B  1 616 ? 196.560 164.346 211.903 1.00 60.36  ? 616 HIS A CG  1 
ATOM   6586 N ND1 . HIS B  1 616 ? 197.237 165.138 212.804 1.00 61.60  ? 616 HIS A ND1 1 
ATOM   6587 C CD2 . HIS B  1 616 ? 195.303 164.217 212.386 1.00 58.13  ? 616 HIS A CD2 1 
ATOM   6588 C CE1 . HIS B  1 616 ? 196.425 165.474 213.789 1.00 54.76  ? 616 HIS A CE1 1 
ATOM   6589 N NE2 . HIS B  1 616 ? 195.244 164.927 213.560 1.00 56.04  ? 616 HIS A NE2 1 
ATOM   6590 N N   . LEU B  1 617 ? 196.883 160.785 211.458 1.00 53.59  ? 617 LEU A N   1 
ATOM   6591 C CA  . LEU B  1 617 ? 196.194 159.876 212.367 1.00 53.75  ? 617 LEU A CA  1 
ATOM   6592 C C   . LEU B  1 617 ? 197.154 158.852 212.960 1.00 62.13  ? 617 LEU A C   1 
ATOM   6593 O O   . LEU B  1 617 ? 197.398 158.837 214.171 1.00 69.09  ? 617 LEU A O   1 
ATOM   6594 C CB  . LEU B  1 617 ? 195.049 159.182 211.631 1.00 54.19  ? 617 LEU A CB  1 
ATOM   6595 C CG  . LEU B  1 617 ? 193.649 159.720 211.913 1.00 58.88  ? 617 LEU A CG  1 
ATOM   6596 C CD1 . LEU B  1 617 ? 193.605 161.222 211.716 1.00 62.29  ? 617 LEU A CD1 1 
ATOM   6597 C CD2 . LEU B  1 617 ? 192.649 159.043 211.006 1.00 59.40  ? 617 LEU A CD2 1 
ATOM   6598 N N   . ASN B  1 618 ? 197.718 157.993 212.116 1.00 53.84  ? 618 ASN A N   1 
ATOM   6599 C CA  . ASN B  1 618 ? 198.650 156.960 212.548 1.00 52.45  ? 618 ASN A CA  1 
ATOM   6600 C C   . ASN B  1 618 ? 199.882 157.032 211.664 1.00 53.48  ? 618 ASN A C   1 
ATOM   6601 O O   . ASN B  1 618 ? 199.782 156.846 210.448 1.00 62.99  ? 618 ASN A O   1 
ATOM   6602 C CB  . ASN B  1 618 ? 198.010 155.571 212.479 1.00 56.16  ? 618 ASN A CB  1 
ATOM   6603 C CG  . ASN B  1 618 ? 197.185 155.372 211.225 1.00 54.47  ? 618 ASN A CG  1 
ATOM   6604 O OD1 . ASN B  1 618 ? 196.090 155.916 211.098 1.00 48.46  ? 618 ASN A OD1 1 
ATOM   6605 N ND2 . ASN B  1 618 ? 197.710 154.591 210.289 1.00 55.57  ? 618 ASN A ND2 1 
ATOM   6606 N N   . ASN B  1 619 ? 201.034 157.292 212.276 1.00 61.66  ? 619 ASN A N   1 
ATOM   6607 C CA  . ASN B  1 619 ? 202.269 157.550 211.544 1.00 59.46  ? 619 ASN A CA  1 
ATOM   6608 C C   . ASN B  1 619 ? 202.560 156.456 210.525 1.00 67.31  ? 619 ASN A C   1 
ATOM   6609 O O   . ASN B  1 619 ? 202.609 155.271 210.865 1.00 72.31  ? 619 ASN A O   1 
ATOM   6610 C CB  . ASN B  1 619 ? 203.426 157.671 212.539 1.00 61.13  ? 619 ASN A CB  1 
ATOM   6611 C CG  . ASN B  1 619 ? 204.718 158.108 211.885 1.00 68.73  ? 619 ASN A CG  1 
ATOM   6612 O OD1 . ASN B  1 619 ? 204.755 158.420 210.696 1.00 76.12  ? 619 ASN A OD1 1 
ATOM   6613 N ND2 . ASN B  1 619 ? 205.793 158.128 212.663 1.00 71.77  ? 619 ASN A ND2 1 
ATOM   6614 N N   . CYS B  1 620 ? 202.749 156.863 209.272 1.00 63.59  ? 620 CYS A N   1 
ATOM   6615 C CA  . CYS B  1 620 ? 203.159 155.971 208.198 1.00 61.10  ? 620 CYS A CA  1 
ATOM   6616 C C   . CYS B  1 620 ? 204.532 156.386 207.691 1.00 64.18  ? 620 CYS A C   1 
ATOM   6617 O O   . CYS B  1 620 ? 204.859 157.574 207.632 1.00 59.37  ? 620 CYS A O   1 
ATOM   6618 C CB  . CYS B  1 620 ? 202.160 155.982 207.039 1.00 55.11  ? 620 CYS A CB  1 
ATOM   6619 S SG  . CYS B  1 620 ? 200.457 156.283 207.516 1.00 76.36  ? 620 CYS A SG  1 
ATOM   6620 N N   . GLY B  1 621 ? 205.339 155.391 207.329 1.00 74.53  ? 621 GLY A N   1 
ATOM   6621 C CA  . GLY B  1 621 ? 206.711 155.630 206.945 1.00 71.59  ? 621 GLY A CA  1 
ATOM   6622 C C   . GLY B  1 621 ? 207.643 155.941 208.091 1.00 70.06  ? 621 GLY A C   1 
ATOM   6623 O O   . GLY B  1 621 ? 208.859 156.004 207.875 1.00 71.26  ? 621 GLY A O   1 
ATOM   6624 N N   . GLU B  1 622 ? 207.116 156.129 209.302 1.00 69.98  ? 622 GLU A N   1 
ATOM   6625 C CA  . GLU B  1 622 ? 207.921 156.392 210.493 1.00 73.44  ? 622 GLU A CA  1 
ATOM   6626 C C   . GLU B  1 622 ? 208.842 157.593 210.294 1.00 76.64  ? 622 GLU A C   1 
ATOM   6627 O O   . GLU B  1 622 ? 210.000 157.593 210.715 1.00 83.53  ? 622 GLU A O   1 
ATOM   6628 C CB  . GLU B  1 622 ? 208.712 155.149 210.903 1.00 79.30  ? 622 GLU A CB  1 
ATOM   6629 C CG  . GLU B  1 622 ? 207.840 154.008 211.411 1.00 79.46  ? 622 GLU A CG  1 
ATOM   6630 C CD  . GLU B  1 622 ? 207.647 152.908 210.385 1.00 83.51  ? 622 GLU A CD  1 
ATOM   6631 O OE1 . GLU B  1 622 ? 207.897 153.156 209.187 1.00 83.12  ? 622 GLU A OE1 1 
ATOM   6632 O OE2 . GLU B  1 622 ? 207.241 151.794 210.777 1.00 83.28  ? 622 GLU A OE2 1 
ATOM   6633 N N   . PHE B  1 623 ? 208.320 158.629 209.633 1.00 57.97  ? 623 PHE A N   1 
ATOM   6634 C CA  . PHE B  1 623 ? 209.061 159.882 209.529 1.00 58.47  ? 623 PHE A CA  1 
ATOM   6635 C C   . PHE B  1 623 ? 209.204 160.545 210.892 1.00 63.26  ? 623 PHE A C   1 
ATOM   6636 O O   . PHE B  1 623 ? 210.267 161.083 211.224 1.00 63.55  ? 623 PHE A O   1 
ATOM   6637 C CB  . PHE B  1 623 ? 208.366 160.830 208.553 1.00 54.06  ? 623 PHE A CB  1 
ATOM   6638 C CG  . PHE B  1 623 ? 208.431 160.387 207.122 1.00 50.84  ? 623 PHE A CG  1 
ATOM   6639 C CD1 . PHE B  1 623 ? 207.450 159.570 206.592 1.00 56.71  ? 623 PHE A CD1 1 
ATOM   6640 C CD2 . PHE B  1 623 ? 209.469 160.793 206.305 1.00 53.61  ? 623 PHE A CD2 1 
ATOM   6641 C CE1 . PHE B  1 623 ? 207.506 159.166 205.276 1.00 60.75  ? 623 PHE A CE1 1 
ATOM   6642 C CE2 . PHE B  1 623 ? 209.529 160.391 204.990 1.00 52.26  ? 623 PHE A CE2 1 
ATOM   6643 C CZ  . PHE B  1 623 ? 208.547 159.577 204.474 1.00 57.45  ? 623 PHE A CZ  1 
ATOM   6644 N N   . ARG B  1 624 ? 208.146 160.511 211.693 1.00 75.91  ? 624 ARG A N   1 
ATOM   6645 C CA  . ARG B  1 624 ? 208.114 161.175 212.986 1.00 78.30  ? 624 ARG A CA  1 
ATOM   6646 C C   . ARG B  1 624 ? 208.620 160.246 214.080 1.00 74.23  ? 624 ARG A C   1 
ATOM   6647 O O   . ARG B  1 624 ? 208.461 159.025 214.011 1.00 70.46  ? 624 ARG A O   1 
ATOM   6648 C CB  . ARG B  1 624 ? 206.691 161.633 213.307 1.00 75.60  ? 624 ARG A CB  1 
ATOM   6649 C CG  . ARG B  1 624 ? 206.595 162.758 214.317 1.00 72.99  ? 624 ARG A CG  1 
ATOM   6650 C CD  . ARG B  1 624 ? 205.364 163.619 214.067 1.00 73.74  ? 624 ARG A CD  1 
ATOM   6651 N NE  . ARG B  1 624 ? 204.135 162.836 213.999 1.00 75.17  ? 624 ARG A NE  1 
ATOM   6652 C CZ  . ARG B  1 624 ? 203.522 162.496 212.873 1.00 76.96  ? 624 ARG A CZ  1 
ATOM   6653 N NH1 . ARG B  1 624 ? 204.002 162.849 211.692 1.00 76.41  ? 624 ARG A NH1 1 
ATOM   6654 N NH2 . ARG B  1 624 ? 202.402 161.781 212.934 1.00 76.62  ? 624 ARG A NH2 1 
ATOM   6655 N N   . ALA B  1 625 ? 209.243 160.844 215.098 1.00 89.00  ? 625 ALA A N   1 
ATOM   6656 C CA  . ALA B  1 625 ? 209.728 160.061 216.230 1.00 93.96  ? 625 ALA A CA  1 
ATOM   6657 C C   . ALA B  1 625 ? 208.575 159.429 217.000 1.00 93.71  ? 625 ALA A C   1 
ATOM   6658 O O   . ALA B  1 625 ? 208.664 158.272 217.425 1.00 93.22  ? 625 ALA A O   1 
ATOM   6659 C CB  . ALA B  1 625 ? 210.573 160.938 217.152 1.00 92.00  ? 625 ALA A CB  1 
ATOM   6660 N N   . VAL B  1 626 ? 207.489 160.172 217.190 1.00 94.19  ? 626 VAL A N   1 
ATOM   6661 C CA  . VAL B  1 626 ? 206.338 159.675 217.936 1.00 98.06  ? 626 VAL A CA  1 
ATOM   6662 C C   . VAL B  1 626 ? 205.614 158.589 217.149 1.00 95.06  ? 626 VAL A C   1 
ATOM   6663 O O   . VAL B  1 626 ? 204.658 157.987 217.639 1.00 93.53  ? 626 VAL A O   1 
ATOM   6664 C CB  . VAL B  1 626 ? 205.372 160.819 218.293 1.00 95.86  ? 626 VAL A CB  1 
ATOM   6665 C CG1 . VAL B  1 626 ? 206.136 161.996 218.879 1.00 93.47  ? 626 VAL A CG1 1 
ATOM   6666 C CG2 . VAL B  1 626 ? 204.581 161.248 217.067 1.00 94.71  ? 626 VAL A CG2 1 
HETATM 6667 C C1  . CLR C  2 .   ? 191.851 209.347 200.645 1.00 43.47  ? 801 CLR B C1  1 
HETATM 6668 C C2  . CLR C  2 .   ? 191.544 208.431 201.825 1.00 49.38  ? 801 CLR B C2  1 
HETATM 6669 C C3  . CLR C  2 .   ? 190.811 209.187 202.914 1.00 46.53  ? 801 CLR B C3  1 
HETATM 6670 C C4  . CLR C  2 .   ? 189.541 209.804 202.338 1.00 46.71  ? 801 CLR B C4  1 
HETATM 6671 C C5  . CLR C  2 .   ? 189.825 210.653 201.128 1.00 41.60  ? 801 CLR B C5  1 
HETATM 6672 C C6  . CLR C  2 .   ? 189.651 211.970 201.196 1.00 36.15  ? 801 CLR B C6  1 
HETATM 6673 C C7  . CLR C  2 .   ? 189.831 212.905 200.052 1.00 33.91  ? 801 CLR B C7  1 
HETATM 6674 C C8  . CLR C  2 .   ? 190.056 212.169 198.740 1.00 36.29  ? 801 CLR B C8  1 
HETATM 6675 C C9  . CLR C  2 .   ? 191.048 211.014 198.937 1.00 40.42  ? 801 CLR B C9  1 
HETATM 6676 C C10 . CLR C  2 .   ? 190.601 209.983 200.008 1.00 37.12  ? 801 CLR B C10 1 
HETATM 6677 C C11 . CLR C  2 .   ? 191.400 210.379 197.587 1.00 41.42  ? 801 CLR B C11 1 
HETATM 6678 C C12 . CLR C  2 .   ? 191.871 211.385 196.532 1.00 42.37  ? 801 CLR B C12 1 
HETATM 6679 C C13 . CLR C  2 .   ? 190.862 212.515 196.312 1.00 33.27  ? 801 CLR B C13 1 
HETATM 6680 C C14 . CLR C  2 .   ? 190.607 213.125 197.698 1.00 32.79  ? 801 CLR B C14 1 
HETATM 6681 C C15 . CLR C  2 .   ? 189.834 214.402 197.417 1.00 35.34  ? 801 CLR B C15 1 
HETATM 6682 C C16 . CLR C  2 .   ? 190.440 214.900 196.093 1.00 31.18  ? 801 CLR B C16 1 
HETATM 6683 C C17 . CLR C  2 .   ? 191.353 213.771 195.546 1.00 29.81  ? 801 CLR B C17 1 
HETATM 6684 C C18 . CLR C  2 .   ? 189.582 211.986 195.665 1.00 41.81  ? 801 CLR B C18 1 
HETATM 6685 C C19 . CLR C  2 .   ? 189.736 208.868 199.404 1.00 34.67  ? 801 CLR B C19 1 
HETATM 6686 C C20 . CLR C  2 .   ? 191.376 213.776 194.010 1.00 37.18  ? 801 CLR B C20 1 
HETATM 6687 C C21 . CLR C  2 .   ? 192.496 212.929 193.411 1.00 36.02  ? 801 CLR B C21 1 
HETATM 6688 C C22 . CLR C  2 .   ? 191.441 215.227 193.502 1.00 39.78  ? 801 CLR B C22 1 
HETATM 6689 C C23 . CLR C  2 .   ? 192.663 215.619 192.675 1.00 41.71  ? 801 CLR B C23 1 
HETATM 6690 C C24 . CLR C  2 .   ? 192.344 215.740 191.188 1.00 39.77  ? 801 CLR B C24 1 
HETATM 6691 C C25 . CLR C  2 .   ? 192.107 217.162 190.680 1.00 46.93  ? 801 CLR B C25 1 
HETATM 6692 C C26 . CLR C  2 .   ? 193.351 218.022 190.884 1.00 42.53  ? 801 CLR B C26 1 
HETATM 6693 C C27 . CLR C  2 .   ? 191.677 217.187 189.216 1.00 46.36  ? 801 CLR B C27 1 
HETATM 6694 O O1  . CLR C  2 .   ? 190.532 208.297 203.975 1.00 43.30  ? 801 CLR B O1  1 
HETATM 6695 P P   . 3PE D  3 .   ? 170.402 198.993 204.545 1.00 81.25  ? 802 3PE B P   1 
HETATM 6696 N N   . 3PE D  3 .   ? 166.671 198.299 206.938 1.00 61.38  ? 802 3PE B N   1 
HETATM 6697 O O11 . 3PE D  3 .   ? 171.017 199.839 203.277 1.00 62.76  ? 802 3PE B O11 1 
HETATM 6698 O O12 . 3PE D  3 .   ? 170.143 197.622 204.023 1.00 63.62  ? 802 3PE B O12 1 
HETATM 6699 O O13 . 3PE D  3 .   ? 168.967 199.772 204.802 1.00 72.54  ? 802 3PE B O13 1 
HETATM 6700 O O14 . 3PE D  3 .   ? 171.205 199.273 205.770 1.00 62.94  ? 802 3PE B O14 1 
HETATM 6701 C C11 . 3PE D  3 .   ? 168.427 199.827 206.101 1.00 63.41  ? 802 3PE B C11 1 
HETATM 6702 C C12 . 3PE D  3 .   ? 168.096 198.419 206.539 1.00 64.29  ? 802 3PE B C12 1 
HETATM 6703 C C1  . 3PE D  3 .   ? 172.115 200.682 203.530 1.00 62.89  ? 802 3PE B C1  1 
HETATM 6704 C C2  . 3PE D  3 .   ? 172.462 201.518 202.304 1.00 62.74  ? 802 3PE B C2  1 
HETATM 6705 C C3  . 3PE D  3 .   ? 173.782 202.218 202.545 1.00 63.47  ? 802 3PE B C3  1 
HETATM 6706 O O31 . 3PE D  3 .   ? 173.731 203.487 201.902 1.00 58.59  ? 802 3PE B O31 1 
HETATM 6707 O O32 . 3PE D  3 .   ? 175.952 203.682 202.003 1.00 52.30  ? 802 3PE B O32 1 
HETATM 6708 C C31 . 3PE D  3 .   ? 174.883 204.098 201.638 1.00 58.07  ? 802 3PE B C31 1 
HETATM 6709 C C32 . 3PE D  3 .   ? 174.666 205.347 200.835 1.00 59.74  ? 802 3PE B C32 1 
HETATM 6710 C C33 . 3PE D  3 .   ? 174.328 205.090 199.377 1.00 64.60  ? 802 3PE B C33 1 
HETATM 6711 C C34 . 3PE D  3 .   ? 172.825 205.086 199.128 1.00 54.60  ? 802 3PE B C34 1 
HETATM 6712 C C35 . 3PE D  3 .   ? 172.462 205.216 197.656 1.00 46.90  ? 802 3PE B C35 1 
HETATM 6713 C C36 . 3PE D  3 .   ? 173.101 204.131 196.803 1.00 49.40  ? 802 3PE B C36 1 
HETATM 6714 C C37 . 3PE D  3 .   ? 173.132 204.460 195.317 1.00 59.06  ? 802 3PE B C37 1 
HETATM 6715 C C38 . 3PE D  3 .   ? 171.799 204.986 194.805 1.00 61.14  ? 802 3PE B C38 1 
HETATM 6716 C C39 . 3PE D  3 .   ? 171.392 204.411 193.455 1.00 63.25  ? 802 3PE B C39 1 
HETATM 6717 C C3A . 3PE D  3 .   ? 172.033 205.144 192.287 1.00 57.28  ? 802 3PE B C3A 1 
HETATM 6718 C C3B . 3PE D  3 .   ? 171.097 206.130 191.604 1.00 59.76  ? 802 3PE B C3B 1 
HETATM 6719 C C3C . 3PE D  3 .   ? 169.854 205.453 191.044 1.00 63.65  ? 802 3PE B C3C 1 
HETATM 6720 C C3D . 3PE D  3 .   ? 169.026 206.346 190.131 1.00 63.29  ? 802 3PE B C3D 1 
HETATM 6721 C C3E . 3PE D  3 .   ? 169.765 206.744 188.860 1.00 62.61  ? 802 3PE B C3E 1 
HETATM 6722 C C3F . 3PE D  3 .   ? 168.851 207.332 187.794 1.00 64.60  ? 802 3PE B C3F 1 
HETATM 6723 C C3G . 3PE D  3 .   ? 167.581 206.516 187.597 1.00 65.12  ? 802 3PE B C3G 1 
HETATM 6724 C C3H . 3PE D  3 .   ? 166.773 206.922 186.372 1.00 62.05  ? 802 3PE B C3H 1 
HETATM 6725 C C3I . 3PE D  3 .   ? 165.455 206.170 186.264 1.00 61.17  ? 802 3PE B C3I 1 
HETATM 6726 O O21 . 3PE D  3 .   ? 172.642 200.715 201.127 1.00 66.38  ? 802 3PE B O21 1 
HETATM 6727 O O22 . 3PE D  3 .   ? 173.638 201.925 199.528 1.00 71.29  ? 802 3PE B O22 1 
HETATM 6728 C C21 . 3PE D  3 .   ? 172.728 201.222 199.911 1.00 64.85  ? 802 3PE B C21 1 
HETATM 6729 C C22 . 3PE D  3 .   ? 171.582 200.808 199.038 1.00 59.88  ? 802 3PE B C22 1 
HETATM 6730 C C23 . 3PE D  3 .   ? 171.960 200.710 197.570 1.00 54.99  ? 802 3PE B C23 1 
HETATM 6731 C C24 . 3PE D  3 .   ? 171.089 199.705 196.830 1.00 60.88  ? 802 3PE B C24 1 
HETATM 6732 C C25 . 3PE D  3 .   ? 171.861 198.912 195.787 1.00 58.60  ? 802 3PE B C25 1 
HETATM 6733 C C26 . 3PE D  3 .   ? 172.539 199.807 194.761 1.00 60.06  ? 802 3PE B C26 1 
HETATM 6734 C C27 . 3PE D  3 .   ? 171.656 200.158 193.572 1.00 54.26  ? 802 3PE B C27 1 
HETATM 6735 C C28 . 3PE D  3 .   ? 171.336 198.951 192.701 1.00 51.96  ? 802 3PE B C28 1 
HETATM 6736 C C29 . 3PE D  3 .   ? 171.549 199.202 191.215 1.00 49.87  ? 802 3PE B C29 1 
HETATM 6737 C C2A . 3PE D  3 .   ? 170.706 200.347 190.669 1.00 56.16  ? 802 3PE B C2A 1 
HETATM 6738 C C2B . 3PE D  3 .   ? 170.340 200.171 189.202 1.00 62.58  ? 802 3PE B C2B 1 
HETATM 6739 C C2C . 3PE D  3 .   ? 169.481 201.299 188.643 1.00 64.58  ? 802 3PE B C2C 1 
HETATM 6740 C C2D . 3PE D  3 .   ? 168.999 201.024 187.224 1.00 59.72  ? 802 3PE B C2D 1 
HETATM 6741 C C2E . 3PE D  3 .   ? 168.804 202.277 186.381 1.00 56.11  ? 802 3PE B C2E 1 
HETATM 6742 C C2F . 3PE D  3 .   ? 168.590 201.966 184.905 1.00 58.93  ? 802 3PE B C2F 1 
HETATM 6743 C C2G . 3PE D  3 .   ? 168.603 203.195 184.006 1.00 59.51  ? 802 3PE B C2G 1 
HETATM 6744 C C2H . 3PE D  3 .   ? 169.999 203.605 183.553 1.00 59.36  ? 802 3PE B C2H 1 
HETATM 6745 C C2I . 3PE D  3 .   ? 169.978 204.517 182.335 1.00 53.71  ? 802 3PE B C2I 1 
HETATM 6746 P P   . 3PE E  3 .   ? 183.310 184.869 162.128 1.00 97.53  ? 803 3PE B P   1 
HETATM 6747 N N   . 3PE E  3 .   ? 188.315 184.496 161.596 1.00 75.41  ? 803 3PE B N   1 
HETATM 6748 O O11 . 3PE E  3 .   ? 183.183 184.967 163.763 1.00 79.15  ? 803 3PE B O11 1 
HETATM 6749 O O12 . 3PE E  3 .   ? 182.259 183.894 161.716 1.00 75.73  ? 803 3PE B O12 1 
HETATM 6750 O O13 . 3PE E  3 .   ? 184.805 184.182 161.956 1.00 82.93  ? 803 3PE B O13 1 
HETATM 6751 O O14 . 3PE E  3 .   ? 183.449 186.236 161.547 1.00 77.81  ? 803 3PE B O14 1 
HETATM 6752 C C11 . 3PE E  3 .   ? 185.883 184.959 161.490 1.00 72.84  ? 803 3PE B C11 1 
HETATM 6753 C C12 . 3PE E  3 .   ? 187.002 184.024 161.089 1.00 75.25  ? 803 3PE B C12 1 
HETATM 6754 C C1  . 3PE E  3 .   ? 183.109 186.235 164.371 1.00 72.00  ? 803 3PE B C1  1 
HETATM 6755 C C2  . 3PE E  3 .   ? 183.412 186.078 165.855 1.00 74.06  ? 803 3PE B C2  1 
HETATM 6756 C C3  . 3PE E  3 .   ? 184.541 186.990 166.286 1.00 74.50  ? 803 3PE B C3  1 
HETATM 6757 O O31 . 3PE E  3 .   ? 185.652 186.685 165.447 1.00 80.29  ? 803 3PE B O31 1 
HETATM 6758 O O32 . 3PE E  3 .   ? 187.686 187.591 165.331 1.00 77.06  ? 803 3PE B O32 1 
HETATM 6759 C C31 . 3PE E  3 .   ? 186.882 186.903 165.907 1.00 77.45  ? 803 3PE B C31 1 
HETATM 6760 C C32 . 3PE E  3 .   ? 187.115 186.187 167.209 1.00 71.20  ? 803 3PE B C32 1 
HETATM 6761 C C33 . 3PE E  3 .   ? 188.473 186.462 167.832 1.00 68.12  ? 803 3PE B C33 1 
HETATM 6762 C C34 . 3PE E  3 .   ? 188.439 186.262 169.341 1.00 69.57  ? 803 3PE B C34 1 
HETATM 6763 C C35 . 3PE E  3 .   ? 187.218 186.891 169.995 1.00 68.30  ? 803 3PE B C35 1 
HETATM 6764 C C36 . 3PE E  3 .   ? 187.386 187.072 171.496 1.00 70.78  ? 803 3PE B C36 1 
HETATM 6765 C C37 . 3PE E  3 .   ? 186.181 187.713 172.169 1.00 69.32  ? 803 3PE B C37 1 
HETATM 6766 C C38 . 3PE E  3 .   ? 186.397 187.927 173.660 1.00 71.20  ? 803 3PE B C38 1 
HETATM 6767 C C39 . 3PE E  3 .   ? 185.107 187.948 174.466 1.00 70.84  ? 803 3PE B C39 1 
HETATM 6768 C C3A . 3PE E  3 .   ? 185.302 187.405 175.874 1.00 67.95  ? 803 3PE B C3A 1 
HETATM 6769 C C3B . 3PE E  3 .   ? 184.004 187.080 176.596 1.00 70.49  ? 803 3PE B C3B 1 
HETATM 6770 C C3C . 3PE E  3 .   ? 184.259 186.419 177.942 1.00 72.12  ? 803 3PE B C3C 1 
HETATM 6771 C C3D . 3PE E  3 .   ? 183.087 186.494 178.908 1.00 68.57  ? 803 3PE B C3D 1 
HETATM 6772 C C3E . 3PE E  3 .   ? 183.506 186.188 180.337 1.00 64.11  ? 803 3PE B C3E 1 
HETATM 6773 C C3F . 3PE E  3 .   ? 182.354 186.163 181.328 1.00 61.81  ? 803 3PE B C3F 1 
HETATM 6774 C C3G . 3PE E  3 .   ? 182.838 186.076 182.767 1.00 64.33  ? 803 3PE B C3G 1 
HETATM 6775 C C3H . 3PE E  3 .   ? 181.836 185.415 183.701 1.00 70.58  ? 803 3PE B C3H 1 
HETATM 6776 C C3I . 3PE E  3 .   ? 181.340 184.076 183.174 1.00 80.42  ? 803 3PE B C3I 1 
HETATM 6777 O O21 . 3PE E  3 .   ? 182.295 186.439 166.676 1.00 77.92  ? 803 3PE B O21 1 
HETATM 6778 O O22 . 3PE E  3 .   ? 180.695 184.892 166.735 1.00 77.22  ? 803 3PE B O22 1 
HETATM 6779 C C21 . 3PE E  3 .   ? 181.579 185.517 167.282 1.00 76.78  ? 803 3PE B C21 1 
HETATM 6780 C C22 . 3PE E  3 .   ? 181.994 185.355 168.715 1.00 72.51  ? 803 3PE B C22 1 
HETATM 6781 C C23 . 3PE E  3 .   ? 182.373 186.660 169.390 1.00 74.29  ? 803 3PE B C23 1 
HETATM 6782 C C24 . 3PE E  3 .   ? 182.605 186.474 170.881 1.00 71.01  ? 803 3PE B C24 1 
HETATM 6783 C C25 . 3PE E  3 .   ? 181.380 186.794 171.725 1.00 72.38  ? 803 3PE B C25 1 
HETATM 6784 C C26 . 3PE E  3 .   ? 181.748 187.463 173.042 1.00 73.06  ? 803 3PE B C26 1 
HETATM 6785 C C27 . 3PE E  3 .   ? 180.586 188.196 173.696 1.00 69.82  ? 803 3PE B C27 1 
HETATM 6786 C C28 . 3PE E  3 .   ? 179.458 187.258 174.099 1.00 73.41  ? 803 3PE B C28 1 
HETATM 6787 C C29 . 3PE E  3 .   ? 178.175 187.978 174.481 1.00 71.09  ? 803 3PE B C29 1 
HETATM 6788 C C2A . 3PE E  3 .   ? 177.017 187.020 174.728 1.00 72.54  ? 803 3PE B C2A 1 
HETATM 6789 C C2B . 3PE E  3 .   ? 175.697 187.730 174.983 1.00 75.03  ? 803 3PE B C2B 1 
HETATM 6790 C C2C . 3PE E  3 .   ? 175.862 188.970 175.852 1.00 78.61  ? 803 3PE B C2C 1 
HETATM 6791 C C2D . 3PE E  3 .   ? 174.553 189.685 176.153 1.00 76.39  ? 803 3PE B C2D 1 
HETATM 6792 C C2E . 3PE E  3 .   ? 174.117 189.520 177.602 1.00 71.48  ? 803 3PE B C2E 1 
HETATM 6793 C C2F . 3PE E  3 .   ? 173.334 190.711 178.133 1.00 66.26  ? 803 3PE B C2F 1 
HETATM 6794 C C2G . 3PE E  3 .   ? 173.143 190.652 179.640 1.00 71.71  ? 803 3PE B C2G 1 
HETATM 6795 C C2H . 3PE E  3 .   ? 172.357 191.832 180.190 1.00 74.49  ? 803 3PE B C2H 1 
HETATM 6796 C C2I . 3PE E  3 .   ? 172.249 191.805 181.707 1.00 72.40  ? 803 3PE B C2I 1 
HETATM 6797 C C1  . CLR F  2 .   ? 159.312 225.583 175.456 1.00 70.52  ? 804 CLR B C1  1 
HETATM 6798 C C2  . CLR F  2 .   ? 159.243 225.509 173.934 1.00 70.11  ? 804 CLR B C2  1 
HETATM 6799 C C3  . CLR F  2 .   ? 160.560 225.918 173.301 1.00 70.72  ? 804 CLR B C3  1 
HETATM 6800 C C4  . CLR F  2 .   ? 161.701 225.083 173.873 1.00 68.15  ? 804 CLR B C4  1 
HETATM 6801 C C5  . CLR F  2 .   ? 161.730 225.130 175.376 1.00 71.46  ? 804 CLR B C5  1 
HETATM 6802 C C6  . CLR F  2 .   ? 162.712 225.775 175.996 1.00 69.93  ? 804 CLR B C6  1 
HETATM 6803 C C7  . CLR F  2 .   ? 162.912 225.773 177.471 1.00 70.17  ? 804 CLR B C7  1 
HETATM 6804 C C8  . CLR F  2 .   ? 161.931 224.850 178.178 1.00 62.82  ? 804 CLR B C8  1 
HETATM 6805 C C9  . CLR F  2 .   ? 160.521 225.036 177.600 1.00 66.94  ? 804 CLR B C9  1 
HETATM 6806 C C10 . CLR F  2 .   ? 160.443 224.738 176.078 1.00 75.32  ? 804 CLR B C10 1 
HETATM 6807 C C11 . CLR F  2 .   ? 159.491 224.248 178.417 1.00 66.84  ? 804 CLR B C11 1 
HETATM 6808 C C12 . CLR F  2 .   ? 159.583 224.464 179.929 1.00 67.47  ? 804 CLR B C12 1 
HETATM 6809 C C13 . CLR F  2 .   ? 160.993 224.210 180.472 1.00 64.66  ? 804 CLR B C13 1 
HETATM 6810 C C14 . CLR F  2 .   ? 161.919 225.127 179.670 1.00 59.18  ? 804 CLR B C14 1 
HETATM 6811 C C15 . CLR F  2 .   ? 163.229 225.033 180.428 1.00 65.75  ? 804 CLR B C15 1 
HETATM 6812 C C16 . CLR F  2 .   ? 162.775 225.086 181.897 1.00 66.70  ? 804 CLR B C16 1 
HETATM 6813 C C17 . CLR F  2 .   ? 161.279 224.670 181.929 1.00 65.05  ? 804 CLR B C17 1 
HETATM 6814 C C18 . CLR F  2 .   ? 161.421 222.754 180.293 1.00 72.36  ? 804 CLR B C18 1 
HETATM 6815 C C19 . CLR F  2 .   ? 160.181 223.250 175.803 1.00 71.41  ? 804 CLR B C19 1 
HETATM 6816 C C20 . CLR F  2 .   ? 160.997 223.723 183.107 1.00 65.69  ? 804 CLR B C20 1 
HETATM 6817 C C21 . CLR F  2 .   ? 159.521 223.386 183.303 1.00 64.62  ? 804 CLR B C21 1 
HETATM 6818 C C22 . CLR F  2 .   ? 161.554 224.333 184.400 1.00 66.24  ? 804 CLR B C22 1 
HETATM 6819 C C23 . CLR F  2 .   ? 160.707 225.452 184.996 1.00 73.29  ? 804 CLR B C23 1 
HETATM 6820 C C24 . CLR F  2 .   ? 160.805 225.509 186.516 1.00 71.30  ? 804 CLR B C24 1 
HETATM 6821 C C25 . CLR F  2 .   ? 159.832 226.480 187.189 1.00 68.63  ? 804 CLR B C25 1 
HETATM 6822 C C26 . CLR F  2 .   ? 158.393 226.134 186.815 1.00 68.85  ? 804 CLR B C26 1 
HETATM 6823 C C27 . CLR F  2 .   ? 159.993 226.505 188.706 1.00 66.73  ? 804 CLR B C27 1 
HETATM 6824 O O1  . CLR F  2 .   ? 160.453 225.764 171.901 1.00 70.46  ? 804 CLR B O1  1 
HETATM 6825 C C1  . CLR G  2 .   ? 175.419 181.178 168.379 1.00 83.05  ? 805 CLR B C1  1 
HETATM 6826 C C2  . CLR G  2 .   ? 174.953 180.871 166.961 1.00 84.95  ? 805 CLR B C2  1 
HETATM 6827 C C3  . CLR G  2 .   ? 175.777 181.650 165.957 1.00 84.98  ? 805 CLR B C3  1 
HETATM 6828 C C4  . CLR G  2 .   ? 177.248 181.278 166.118 1.00 82.06  ? 805 CLR B C4  1 
HETATM 6829 C C5  . CLR G  2 .   ? 177.733 181.511 167.524 1.00 82.76  ? 805 CLR B C5  1 
HETATM 6830 C C6  . CLR G  2 .   ? 178.845 182.212 167.736 1.00 80.82  ? 805 CLR B C6  1 
HETATM 6831 C C7  . CLR G  2 .   ? 179.398 182.552 169.079 1.00 81.42  ? 805 CLR B C7  1 
HETATM 6832 C C8  . CLR G  2 .   ? 178.799 181.715 170.204 1.00 83.17  ? 805 CLR B C8  1 
HETATM 6833 C C9  . CLR G  2 .   ? 177.287 181.549 170.007 1.00 78.06  ? 805 CLR B C9  1 
HETATM 6834 C C10 . CLR G  2 .   ? 176.914 180.899 168.649 1.00 82.57  ? 805 CLR B C10 1 
HETATM 6835 C C11 . CLR G  2 .   ? 176.655 180.846 171.214 1.00 75.57  ? 805 CLR B C11 1 
HETATM 6836 C C12 . CLR G  2 .   ? 176.992 181.504 172.555 1.00 80.18  ? 805 CLR B C12 1 
HETATM 6837 C C13 . CLR G  2 .   ? 178.502 181.645 172.768 1.00 82.34  ? 805 CLR B C13 1 
HETATM 6838 C C14 . CLR G  2 .   ? 179.053 182.387 171.541 1.00 83.03  ? 805 CLR B C14 1 
HETATM 6839 C C15 . CLR G  2 .   ? 180.488 182.728 171.918 1.00 80.92  ? 805 CLR B C15 1 
HETATM 6840 C C16 . CLR G  2 .   ? 180.408 182.988 173.433 1.00 79.64  ? 805 CLR B C16 1 
HETATM 6841 C C17 . CLR G  2 .   ? 178.968 182.615 173.884 1.00 79.98  ? 805 CLR B C17 1 
HETATM 6842 C C18 . CLR G  2 .   ? 179.161 180.276 172.958 1.00 78.21  ? 805 CLR B C18 1 
HETATM 6843 C C19 . CLR G  2 .   ? 177.157 179.383 168.654 1.00 81.18  ? 805 CLR B C19 1 
HETATM 6844 C C20 . CLR G  2 .   ? 178.909 182.173 175.356 1.00 79.88  ? 805 CLR B C20 1 
HETATM 6845 C C21 . CLR G  2 .   ? 177.538 182.379 175.994 1.00 75.07  ? 805 CLR B C21 1 
HETATM 6846 C C22 . CLR G  2 .   ? 179.986 182.897 176.177 1.00 78.59  ? 805 CLR B C22 1 
HETATM 6847 C C23 . CLR G  2 .   ? 179.588 184.266 176.719 1.00 78.19  ? 805 CLR B C23 1 
HETATM 6848 C C24 . CLR G  2 .   ? 180.184 184.540 178.094 1.00 80.46  ? 805 CLR B C24 1 
HETATM 6849 C C25 . CLR G  2 .   ? 179.200 184.464 179.263 1.00 82.69  ? 805 CLR B C25 1 
HETATM 6850 C C26 . CLR G  2 .   ? 178.990 183.015 179.693 1.00 81.31  ? 805 CLR B C26 1 
HETATM 6851 C C27 . CLR G  2 .   ? 177.859 185.111 178.931 1.00 82.60  ? 805 CLR B C27 1 
HETATM 6852 O O1  . CLR G  2 .   ? 175.294 181.371 164.659 1.00 84.15  ? 805 CLR B O1  1 
HETATM 6853 C C1  . CLR H  2 .   ? 181.604 232.603 173.294 1.00 83.35  ? 806 CLR B C1  1 
HETATM 6854 C C2  . CLR H  2 .   ? 181.406 232.418 171.794 1.00 83.65  ? 806 CLR B C2  1 
HETATM 6855 C C3  . CLR H  2 .   ? 182.591 232.959 171.019 1.00 85.79  ? 806 CLR B C3  1 
HETATM 6856 C C4  . CLR H  2 .   ? 183.883 232.317 171.518 1.00 85.98  ? 806 CLR B C4  1 
HETATM 6857 C C5  . CLR H  2 .   ? 184.043 232.436 173.012 1.00 85.72  ? 806 CLR B C5  1 
HETATM 6858 C C6  . CLR H  2 .   ? 185.058 233.131 173.522 1.00 85.78  ? 806 CLR B C6  1 
HETATM 6859 C C7  . CLR H  2 .   ? 185.341 233.257 174.980 1.00 88.30  ? 806 CLR B C7  1 
HETATM 6860 C C8  . CLR H  2 .   ? 184.506 232.282 175.799 1.00 87.14  ? 806 CLR B C8  1 
HETATM 6861 C C9  . CLR H  2 .   ? 183.042 232.331 175.340 1.00 86.34  ? 806 CLR B C9  1 
HETATM 6862 C C10 . CLR H  2 .   ? 182.878 231.935 173.848 1.00 86.01  ? 806 CLR B C10 1 
HETATM 6863 C C11 . CLR H  2 .   ? 182.133 231.531 176.286 1.00 83.96  ? 806 CLR B C11 1 
HETATM 6864 C C12 . CLR H  2 .   ? 182.354 231.787 177.783 1.00 77.96  ? 806 CLR B C12 1 
HETATM 6865 C C13 . CLR H  2 .   ? 183.823 231.630 178.179 1.00 81.32  ? 806 CLR B C13 1 
HETATM 6866 C C14 . CLR H  2 .   ? 184.576 232.618 177.276 1.00 83.51  ? 806 CLR B C14 1 
HETATM 6867 C C15 . CLR H  2 .   ? 185.938 232.774 177.927 1.00 84.62  ? 806 CLR B C15 1 
HETATM 6868 C C16 . CLR H  2 .   ? 185.553 232.891 179.410 1.00 86.62  ? 806 CLR B C16 1 
HETATM 6869 C C17 . CLR H  2 .   ? 184.224 232.106 179.603 1.00 82.21  ? 806 CLR B C17 1 
HETATM 6870 C C18 . CLR H  2 .   ? 184.292 230.187 177.967 1.00 86.98  ? 806 CLR B C18 1 
HETATM 6871 C C19 . CLR H  2 .   ? 182.779 230.412 173.671 1.00 82.59  ? 806 CLR B C19 1 
HETATM 6872 C C20 . CLR H  2 .   ? 184.338 231.058 180.724 1.00 83.36  ? 806 CLR B C20 1 
HETATM 6873 C C21 . CLR H  2 .   ? 183.005 230.750 181.402 1.00 82.80  ? 806 CLR B C21 1 
HETATM 6874 C C22 . CLR H  2 .   ? 185.402 231.480 181.753 1.00 81.77  ? 806 CLR B C22 1 
HETATM 6875 C C23 . CLR H  2 .   ? 184.900 232.086 183.059 1.00 77.94  ? 806 CLR B C23 1 
HETATM 6876 C C24 . CLR H  2 .   ? 184.627 233.582 182.940 1.00 80.58  ? 806 CLR B C24 1 
HETATM 6877 C C25 . CLR H  2 .   ? 184.648 234.349 184.262 1.00 84.81  ? 806 CLR B C25 1 
HETATM 6878 C C26 . CLR H  2 .   ? 183.878 233.584 185.334 1.00 83.73  ? 806 CLR B C26 1 
HETATM 6879 C C27 . CLR H  2 .   ? 184.087 235.761 184.118 1.00 81.06  ? 806 CLR B C27 1 
HETATM 6880 O O1  . CLR H  2 .   ? 182.377 232.709 169.645 1.00 81.63  ? 806 CLR B O1  1 
HETATM 6881 P P   . 3PE I  3 .   ? 190.410 196.680 204.996 1.00 92.37  ? 807 3PE B P   1 
HETATM 6882 N N   . 3PE I  3 .   ? 185.855 195.128 206.154 1.00 62.68  ? 807 3PE B N   1 
HETATM 6883 O O11 . 3PE I  3 .   ? 189.911 196.084 203.549 1.00 69.71  ? 807 3PE B O11 1 
HETATM 6884 O O12 . 3PE I  3 .   ? 191.276 195.615 205.581 1.00 64.25  ? 807 3PE B O12 1 
HETATM 6885 O O13 . 3PE I  3 .   ? 188.979 196.747 205.822 1.00 75.68  ? 807 3PE B O13 1 
HETATM 6886 O O14 . 3PE I  3 .   ? 190.832 198.102 204.842 1.00 66.85  ? 807 3PE B O14 1 
HETATM 6887 C C11 . 3PE I  3 .   ? 187.793 196.329 205.189 1.00 64.43  ? 807 3PE B C11 1 
HETATM 6888 C C12 . 3PE I  3 .   ? 186.674 196.365 206.205 1.00 64.72  ? 807 3PE B C12 1 
HETATM 6889 C C1  . 3PE I  3 .   ? 190.872 195.738 202.581 1.00 63.31  ? 807 3PE B C1  1 
HETATM 6890 C C2  . 3PE I  3 .   ? 190.477 196.388 201.263 1.00 59.42  ? 807 3PE B C2  1 
HETATM 6891 C C3  . 3PE I  3 .   ? 190.008 195.364 200.252 1.00 60.90  ? 807 3PE B C3  1 
HETATM 6892 O O31 . 3PE I  3 .   ? 190.213 195.931 198.962 1.00 63.62  ? 807 3PE B O31 1 
HETATM 6893 O O32 . 3PE I  3 .   ? 188.115 195.535 198.311 1.00 54.46  ? 807 3PE B O32 1 
HETATM 6894 C C31 . 3PE I  3 .   ? 189.164 196.109 198.165 1.00 59.70  ? 807 3PE B C31 1 
HETATM 6895 C C32 . 3PE I  3 .   ? 189.482 197.112 197.093 1.00 61.50  ? 807 3PE B C32 1 
HETATM 6896 C C33 . 3PE I  3 .   ? 188.692 196.940 195.807 1.00 59.58  ? 807 3PE B C33 1 
HETATM 6897 C C34 . 3PE I  3 .   ? 189.229 197.861 194.720 1.00 58.21  ? 807 3PE B C34 1 
HETATM 6898 C C35 . 3PE I  3 .   ? 188.783 197.466 193.321 1.00 60.32  ? 807 3PE B C35 1 
HETATM 6899 C C36 . 3PE I  3 .   ? 188.029 198.579 192.607 1.00 67.64  ? 807 3PE B C36 1 
HETATM 6900 C C37 . 3PE I  3 .   ? 188.738 199.113 191.368 1.00 62.10  ? 807 3PE B C37 1 
HETATM 6901 C C38 . 3PE I  3 .   ? 188.906 198.057 190.285 1.00 60.84  ? 807 3PE B C38 1 
HETATM 6902 C C39 . 3PE I  3 .   ? 189.604 198.558 189.028 1.00 63.50  ? 807 3PE B C39 1 
HETATM 6903 C C3A . 3PE I  3 .   ? 188.639 199.123 187.995 1.00 63.75  ? 807 3PE B C3A 1 
HETATM 6904 C C3B . 3PE I  3 .   ? 189.318 199.495 186.685 1.00 63.32  ? 807 3PE B C3B 1 
HETATM 6905 C C3C . 3PE I  3 .   ? 188.348 199.641 185.521 1.00 61.14  ? 807 3PE B C3C 1 
HETATM 6906 C C3D . 3PE I  3 .   ? 188.952 199.258 184.176 1.00 61.52  ? 807 3PE B C3D 1 
HETATM 6907 C C3E . 3PE I  3 .   ? 190.388 199.739 184.006 1.00 65.07  ? 807 3PE B C3E 1 
HETATM 6908 C C3F . 3PE I  3 .   ? 191.013 199.347 182.674 1.00 67.92  ? 807 3PE B C3F 1 
HETATM 6909 C C3G . 3PE I  3 .   ? 190.465 200.141 181.497 1.00 65.90  ? 807 3PE B C3G 1 
HETATM 6910 C C3H . 3PE I  3 .   ? 190.948 199.635 180.143 1.00 58.94  ? 807 3PE B C3H 1 
HETATM 6911 C C3I . 3PE I  3 .   ? 192.462 199.693 179.996 1.00 62.55  ? 807 3PE B C3I 1 
HETATM 6912 O O21 . 3PE I  3 .   ? 189.371 197.284 201.424 1.00 60.90  ? 807 3PE B O21 1 
HETATM 6913 O O22 . 3PE I  3 .   ? 188.527 198.643 199.883 1.00 74.67  ? 807 3PE B O22 1 
HETATM 6914 C C21 . 3PE I  3 .   ? 189.313 198.431 200.781 1.00 68.97  ? 807 3PE B C21 1 
HETATM 6915 C C22 . 3PE I  3 .   ? 190.308 199.422 201.313 1.00 62.21  ? 807 3PE B C22 1 
HETATM 6916 C C23 . 3PE I  3 .   ? 191.477 199.755 200.403 1.00 65.09  ? 807 3PE B C23 1 
HETATM 6917 C C24 . 3PE I  3 .   ? 191.025 200.314 199.061 1.00 65.49  ? 807 3PE B C24 1 
HETATM 6918 C C25 . 3PE I  3 .   ? 190.049 201.474 199.192 1.00 55.54  ? 807 3PE B C25 1 
HETATM 6919 C C26 . 3PE I  3 .   ? 189.430 201.859 197.858 1.00 56.37  ? 807 3PE B C26 1 
HETATM 6920 C C27 . 3PE I  3 .   ? 190.459 202.122 196.770 1.00 58.39  ? 807 3PE B C27 1 
HETATM 6921 C C28 . 3PE I  3 .   ? 190.243 201.244 195.546 1.00 60.56  ? 807 3PE B C28 1 
HETATM 6922 C C29 . 3PE I  3 .   ? 190.128 202.027 194.247 1.00 64.18  ? 807 3PE B C29 1 
HETATM 6923 C C2A . 3PE I  3 .   ? 191.409 202.766 193.885 1.00 64.19  ? 807 3PE B C2A 1 
HETATM 6924 C C2B . 3PE I  3 .   ? 191.421 203.275 192.451 1.00 62.74  ? 807 3PE B C2B 1 
HETATM 6925 C C2C . 3PE I  3 .   ? 190.938 202.237 191.448 1.00 59.46  ? 807 3PE B C2C 1 
HETATM 6926 C C2D . 3PE I  3 .   ? 191.235 202.612 190.002 1.00 62.36  ? 807 3PE B C2D 1 
HETATM 6927 C C2E . 3PE I  3 .   ? 190.852 204.047 189.663 1.00 63.53  ? 807 3PE B C2E 1 
HETATM 6928 C C2F . 3PE I  3 .   ? 191.175 204.433 188.224 1.00 65.21  ? 807 3PE B C2F 1 
HETATM 6929 C C2G . 3PE I  3 .   ? 192.521 203.904 187.746 1.00 65.70  ? 807 3PE B C2G 1 
HETATM 6930 C C2H . 3PE I  3 .   ? 193.106 204.696 186.583 1.00 63.00  ? 807 3PE B C2H 1 
HETATM 6931 C C2I . 3PE I  3 .   ? 193.547 206.095 186.988 1.00 63.62  ? 807 3PE B C2I 1 
HETATM 6932 C C1  . CLR J  2 .   ? 177.210 234.645 203.229 1.00 72.14  ? 808 CLR B C1  1 
HETATM 6933 C C2  . CLR J  2 .   ? 177.748 234.276 204.606 1.00 71.85  ? 808 CLR B C2  1 
HETATM 6934 C C3  . CLR J  2 .   ? 177.153 232.966 205.081 1.00 74.24  ? 808 CLR B C3  1 
HETATM 6935 C C4  . CLR J  2 .   ? 177.448 231.866 204.067 1.00 72.73  ? 808 CLR B C4  1 
HETATM 6936 C C5  . CLR J  2 .   ? 176.995 232.232 202.679 1.00 73.18  ? 808 CLR B C5  1 
HETATM 6937 C C6  . CLR J  2 .   ? 176.370 231.337 201.917 1.00 71.51  ? 808 CLR B C6  1 
HETATM 6938 C C7  . CLR J  2 .   ? 176.007 231.538 200.483 1.00 68.82  ? 808 CLR B C7  1 
HETATM 6939 C C8  . CLR J  2 .   ? 176.642 232.780 199.869 1.00 69.39  ? 808 CLR B C8  1 
HETATM 6940 C C9  . CLR J  2 .   ? 176.629 233.931 200.884 1.00 71.35  ? 808 CLR B C9  1 
HETATM 6941 C C10 . CLR J  2 .   ? 177.454 233.575 202.144 1.00 71.68  ? 808 CLR B C10 1 
HETATM 6942 C C11 . CLR J  2 .   ? 177.033 235.262 200.243 1.00 75.18  ? 808 CLR B C11 1 
HETATM 6943 C C12 . CLR J  2 .   ? 176.249 235.592 198.971 1.00 77.48  ? 808 CLR B C12 1 
HETATM 6944 C C13 . CLR J  2 .   ? 176.373 234.474 197.935 1.00 78.44  ? 808 CLR B C13 1 
HETATM 6945 C C14 . CLR J  2 .   ? 175.889 233.183 198.614 1.00 73.38  ? 808 CLR B C14 1 
HETATM 6946 C C15 . CLR J  2 .   ? 175.793 232.171 197.480 1.00 68.72  ? 808 CLR B C15 1 
HETATM 6947 C C16 . CLR J  2 .   ? 175.432 233.032 196.255 1.00 69.05  ? 808 CLR B C16 1 
HETATM 6948 C C17 . CLR J  2 .   ? 175.376 234.501 196.750 1.00 69.48  ? 808 CLR B C17 1 
HETATM 6949 C C18 . CLR J  2 .   ? 177.811 234.357 197.423 1.00 75.79  ? 808 CLR B C18 1 
HETATM 6950 C C19 . CLR J  2 .   ? 178.954 233.484 201.831 1.00 68.19  ? 808 CLR B C19 1 
HETATM 6951 C C20 . CLR J  2 .   ? 175.533 235.541 195.627 1.00 67.24  ? 808 CLR B C20 1 
HETATM 6952 C C21 . CLR J  2 .   ? 174.249 236.338 195.400 1.00 67.43  ? 808 CLR B C21 1 
HETATM 6953 C C22 . CLR J  2 .   ? 176.039 234.881 194.330 1.00 67.01  ? 808 CLR B C22 1 
HETATM 6954 C C23 . CLR J  2 .   ? 175.080 234.805 193.144 1.00 68.23  ? 808 CLR B C23 1 
HETATM 6955 C C24 . CLR J  2 .   ? 175.353 235.880 192.096 1.00 72.08  ? 808 CLR B C24 1 
HETATM 6956 C C25 . CLR J  2 .   ? 176.814 236.049 191.674 1.00 74.15  ? 808 CLR B C25 1 
HETATM 6957 C C26 . CLR J  2 .   ? 177.321 234.797 190.966 1.00 71.50  ? 808 CLR B C26 1 
HETATM 6958 C C27 . CLR J  2 .   ? 177.013 237.269 190.780 1.00 67.00  ? 808 CLR B C27 1 
HETATM 6959 O O1  . CLR J  2 .   ? 177.690 232.663 206.352 1.00 73.13  ? 808 CLR B O1  1 
HETATM 6960 C C1  . CLR K  2 .   ? 167.238 236.809 199.733 1.00 77.31  ? 809 CLR B C1  1 
HETATM 6961 C C2  . CLR K  2 .   ? 167.079 236.820 201.248 1.00 75.70  ? 809 CLR B C2  1 
HETATM 6962 C C3  . CLR K  2 .   ? 165.614 236.858 201.640 1.00 79.34  ? 809 CLR B C3  1 
HETATM 6963 C C4  . CLR K  2 .   ? 164.851 235.706 200.987 1.00 73.91  ? 809 CLR B C4  1 
HETATM 6964 C C5  . CLR K  2 .   ? 165.079 235.626 199.501 1.00 77.89  ? 809 CLR B C5  1 
HETATM 6965 C C6  . CLR K  2 .   ? 164.090 235.280 198.676 1.00 77.46  ? 809 CLR B C6  1 
HETATM 6966 C C7  . CLR K  2 .   ? 164.268 234.913 197.238 1.00 75.89  ? 809 CLR B C7  1 
HETATM 6967 C C8  . CLR K  2 .   ? 165.728 234.669 196.865 1.00 74.05  ? 809 CLR B C8  1 
HETATM 6968 C C9  . CLR K  2 .   ? 166.600 235.748 197.522 1.00 75.14  ? 809 CLR B C9  1 
HETATM 6969 C C10 . CLR K  2 .   ? 166.529 235.617 199.061 1.00 77.65  ? 809 CLR B C10 1 
HETATM 6970 C C11 . CLR K  2 .   ? 168.033 235.758 196.980 1.00 71.72  ? 809 CLR B C11 1 
HETATM 6971 C C12 . CLR K  2 .   ? 168.117 235.729 195.453 1.00 73.43  ? 809 CLR B C12 1 
HETATM 6972 C C13 . CLR K  2 .   ? 167.376 234.517 194.889 1.00 78.32  ? 809 CLR B C13 1 
HETATM 6973 C C14 . CLR K  2 .   ? 165.920 234.656 195.356 1.00 76.54  ? 809 CLR B C14 1 
HETATM 6974 C C15 . CLR K  2 .   ? 165.161 233.616 194.541 1.00 74.16  ? 809 CLR B C15 1 
HETATM 6975 C C16 . CLR K  2 .   ? 165.918 233.569 193.199 1.00 73.83  ? 809 CLR B C16 1 
HETATM 6976 C C17 . CLR K  2 .   ? 167.180 234.462 193.353 1.00 80.53  ? 809 CLR B C17 1 
HETATM 6977 C C18 . CLR K  2 .   ? 168.017 233.215 195.374 1.00 75.00  ? 809 CLR B C18 1 
HETATM 6978 C C19 . CLR K  2 .   ? 167.157 234.305 199.538 1.00 76.23  ? 809 CLR B C19 1 
HETATM 6979 C C20 . CLR K  2 .   ? 168.351 234.003 192.470 1.00 79.00  ? 809 CLR B C20 1 
HETATM 6980 C C21 . CLR K  2 .   ? 169.316 235.136 192.126 1.00 71.61  ? 809 CLR B C21 1 
HETATM 6981 C C22 . CLR K  2 .   ? 167.836 233.312 191.197 1.00 74.37  ? 809 CLR B C22 1 
HETATM 6982 C C23 . CLR K  2 .   ? 167.841 234.147 189.921 1.00 77.16  ? 809 CLR B C23 1 
HETATM 6983 C C24 . CLR K  2 .   ? 168.667 233.502 188.812 1.00 76.48  ? 809 CLR B C24 1 
HETATM 6984 C C25 . CLR K  2 .   ? 170.158 233.850 188.815 1.00 77.89  ? 809 CLR B C25 1 
HETATM 6985 C C26 . CLR K  2 .   ? 170.352 235.352 188.628 1.00 75.50  ? 809 CLR B C26 1 
HETATM 6986 C C27 . CLR K  2 .   ? 170.932 233.092 187.741 1.00 75.50  ? 809 CLR B C27 1 
HETATM 6987 O O1  . CLR K  2 .   ? 165.534 236.809 203.050 1.00 80.04  ? 809 CLR B O1  1 
HETATM 6988 C C1  . LPE L  4 .   ? 176.475 185.322 195.651 1.00 72.88  ? 810 LPE B C1  1 
HETATM 6989 O O1  . LPE L  4 .   ? 176.114 185.247 194.286 1.00 74.47  ? 810 LPE B O1  1 
HETATM 6990 C C2  . LPE L  4 .   ? 175.403 184.596 196.478 1.00 78.10  ? 810 LPE B C2  1 
HETATM 6991 O O2H . LPE L  4 .   ? 176.017 183.850 197.481 1.00 75.13  ? 810 LPE B O2H 1 
HETATM 6992 C C3  . LPE L  4 .   ? 174.462 185.626 197.120 1.00 77.87  ? 810 LPE B C3  1 
HETATM 6993 C C11 . LPE L  4 .   ? 177.047 184.541 193.483 1.00 75.57  ? 810 LPE B C11 1 
HETATM 6994 C C12 . LPE L  4 .   ? 176.627 184.688 191.997 1.00 72.86  ? 810 LPE B C12 1 
HETATM 6995 O O3  . LPE L  4 .   ? 175.243 186.584 197.810 1.00 80.82  ? 810 LPE B O3  1 
HETATM 6996 P P   . LPE L  4 .   ? 174.606 188.103 198.018 1.00 88.22  ? 810 LPE B P   1 
HETATM 6997 O O31 . LPE L  4 .   ? 173.372 188.070 198.814 1.00 71.31  ? 810 LPE B O31 1 
HETATM 6998 O O32 . LPE L  4 .   ? 175.463 188.939 198.856 1.00 77.12  ? 810 LPE B O32 1 
HETATM 6999 O O33 . LPE L  4 .   ? 174.343 188.786 196.526 1.00 80.01  ? 810 LPE B O33 1 
HETATM 7000 C C31 . LPE L  4 .   ? 175.428 188.858 195.620 1.00 72.17  ? 810 LPE B C31 1 
HETATM 7001 C C32 . LPE L  4 .   ? 174.892 188.586 194.193 1.00 75.63  ? 810 LPE B C32 1 
HETATM 7002 N N   . LPE L  4 .   ? 175.733 189.210 193.133 1.00 74.03  ? 810 LPE B N   1 
HETATM 7003 C C1N . LPE L  4 .   ? 175.130 190.541 192.842 1.00 71.89  ? 810 LPE B C1N 1 
HETATM 7004 C C2N . LPE L  4 .   ? 177.147 189.143 193.562 1.00 72.01  ? 810 LPE B C2N 1 
HETATM 7005 C C3N . LPE L  4 .   ? 175.649 188.431 191.877 1.00 71.16  ? 810 LPE B C3N 1 
HETATM 7006 C C13 . LPE L  4 .   ? 177.737 185.356 191.140 1.00 76.44  ? 810 LPE B C13 1 
HETATM 7007 C C14 . LPE L  4 .   ? 179.071 184.559 191.177 1.00 75.10  ? 810 LPE B C14 1 
HETATM 7008 C C15 . LPE L  4 .   ? 179.942 184.806 189.915 1.00 72.26  ? 810 LPE B C15 1 
HETATM 7009 C C16 . LPE L  4 .   ? 179.302 184.217 188.625 1.00 71.69  ? 810 LPE B C16 1 
HETATM 7010 C C17 . LPE L  4 .   ? 178.884 185.319 187.619 1.00 70.83  ? 810 LPE B C17 1 
HETATM 7011 C C18 . LPE L  4 .   ? 180.105 186.020 186.954 1.00 75.30  ? 810 LPE B C18 1 
HETATM 7012 C C19 . LPE L  4 .   ? 179.689 187.237 186.085 1.00 78.41  ? 810 LPE B C19 1 
HETATM 7013 C C20 . LPE L  4 .   ? 178.296 187.056 185.425 1.00 77.31  ? 810 LPE B C20 1 
HETATM 7014 C C21 . LPE L  4 .   ? 178.385 186.353 184.042 1.00 74.19  ? 810 LPE B C21 1 
HETATM 7015 C C22 . LPE L  4 .   ? 177.008 185.819 183.558 1.00 71.08  ? 810 LPE B C22 1 
HETATM 7016 C C23 . LPE L  4 .   ? 176.593 186.403 182.175 1.00 72.89  ? 810 LPE B C23 1 
HETATM 7017 C C24 . LPE L  4 .   ? 175.235 185.837 181.679 1.00 72.74  ? 810 LPE B C24 1 
HETATM 7018 C C25 . LPE L  4 .   ? 174.033 186.702 182.141 1.00 74.71  ? 810 LPE B C25 1 
HETATM 7019 C C26 . LPE L  4 .   ? 173.433 186.219 183.483 1.00 75.07  ? 810 LPE B C26 1 
HETATM 7020 C C27 . LPE L  4 .   ? 172.351 187.174 184.021 1.00 73.88  ? 810 LPE B C27 1 
HETATM 7021 C C28 . LPE L  4 .   ? 171.409 187.673 182.910 1.00 72.87  ? 810 LPE B C28 1 
HETATM 7022 C C1  . PLM M  5 .   ? 178.241 184.831 201.787 1.00 70.50  ? 811 PLM B C1  1 
HETATM 7023 O O1  . PLM M  5 .   ? 177.510 184.799 202.812 1.00 72.92  ? 811 PLM B O1  1 
HETATM 7024 O O2  . PLM M  5 .   ? 178.679 185.833 201.159 1.00 69.10  ? 811 PLM B O2  1 
HETATM 7025 C C2  . PLM M  5 .   ? 178.651 183.422 201.232 1.00 66.78  ? 811 PLM B C2  1 
HETATM 7026 C C3  . PLM M  5 .   ? 178.161 183.107 199.819 1.00 65.79  ? 811 PLM B C3  1 
HETATM 7027 C C4  . PLM M  5 .   ? 179.069 182.149 199.035 1.00 67.60  ? 811 PLM B C4  1 
HETATM 7028 C C5  . PLM M  5 .   ? 178.511 181.770 197.656 1.00 69.32  ? 811 PLM B C5  1 
HETATM 7029 C C6  . PLM M  5 .   ? 179.491 180.995 196.770 1.00 67.29  ? 811 PLM B C6  1 
HETATM 7030 C C7  . PLM M  5 .   ? 180.494 181.884 196.024 1.00 65.54  ? 811 PLM B C7  1 
HETATM 7031 C C8  . PLM M  5 .   ? 180.103 182.180 194.574 1.00 65.35  ? 811 PLM B C8  1 
HETATM 7032 C C9  . PLM M  5 .   ? 181.180 182.937 193.789 1.00 68.45  ? 811 PLM B C9  1 
HETATM 7033 C CA  . PLM M  5 .   ? 182.324 182.050 193.284 1.00 70.17  ? 811 PLM B CA  1 
HETATM 7034 C CB  . PLM M  5 .   ? 182.227 181.710 191.791 1.00 70.14  ? 811 PLM B CB  1 
HETATM 7035 C CC  . PLM M  5 .   ? 183.514 181.110 191.204 1.00 69.58  ? 811 PLM B CC  1 
HETATM 7036 C CD  . PLM M  5 .   ? 183.389 180.718 189.726 1.00 71.21  ? 811 PLM B CD  1 
HETATM 7037 C CE  . PLM M  5 .   ? 182.824 181.835 188.837 1.00 74.92  ? 811 PLM B CE  1 
HETATM 7038 C CF  . PLM M  5 .   ? 182.461 181.372 187.419 1.00 72.11  ? 811 PLM B CF  1 
HETATM 7039 C CG  . PLM M  5 .   ? 181.904 182.495 186.536 1.00 63.51  ? 811 PLM B CG  1 
HETATM 7040 C C1  . CLR N  2 .   ? 155.539 201.622 172.454 1.00 88.03  ? 812 CLR B C1  1 
HETATM 7041 C C2  . CLR N  2 .   ? 154.527 201.571 171.316 1.00 87.60  ? 812 CLR B C2  1 
HETATM 7042 C C3  . CLR N  2 .   ? 155.173 201.995 170.014 1.00 92.05  ? 812 CLR B C3  1 
HETATM 7043 C C4  . CLR N  2 .   ? 156.358 201.082 169.715 1.00 90.14  ? 812 CLR B C4  1 
HETATM 7044 C C5  . CLR N  2 .   ? 157.351 201.062 170.846 1.00 86.55  ? 812 CLR B C5  1 
HETATM 7045 C C6  . CLR N  2 .   ? 158.641 201.292 170.606 1.00 83.78  ? 812 CLR B C6  1 
HETATM 7046 C C7  . CLR N  2 .   ? 159.715 201.298 171.641 1.00 86.88  ? 812 CLR B C7  1 
HETATM 7047 C C8  . CLR N  2 .   ? 159.270 200.697 172.969 1.00 85.93  ? 812 CLR B C8  1 
HETATM 7048 C C9  . CLR N  2 .   ? 157.848 201.159 173.316 1.00 87.17  ? 812 CLR B C9  1 
HETATM 7049 C C10 . CLR N  2 .   ? 156.807 200.769 172.234 1.00 87.93  ? 812 CLR B C10 1 
HETATM 7050 C C11 . CLR N  2 .   ? 157.455 200.715 174.729 1.00 88.08  ? 812 CLR B C11 1 
HETATM 7051 C C12 . CLR N  2 .   ? 158.474 201.101 175.805 1.00 88.81  ? 812 CLR B C12 1 
HETATM 7052 C C13 . CLR N  2 .   ? 159.876 200.583 175.477 1.00 89.11  ? 812 CLR B C13 1 
HETATM 7053 C C14 . CLR N  2 .   ? 160.216 201.118 174.078 1.00 87.60  ? 812 CLR B C14 1 
HETATM 7054 C C15 . CLR N  2 .   ? 161.694 200.803 173.928 1.00 86.77  ? 812 CLR B C15 1 
HETATM 7055 C C16 . CLR N  2 .   ? 162.250 201.164 175.315 1.00 87.63  ? 812 CLR B C16 1 
HETATM 7056 C C17 . CLR N  2 .   ? 161.048 201.179 176.302 1.00 88.85  ? 812 CLR B C17 1 
HETATM 7057 C C18 . CLR N  2 .   ? 159.922 199.054 175.537 1.00 83.81  ? 812 CLR B C18 1 
HETATM 7058 C C19 . CLR N  2 .   ? 156.441 199.279 172.307 1.00 85.89  ? 812 CLR B C19 1 
HETATM 7059 C C20 . CLR N  2 .   ? 161.400 200.548 177.659 1.00 87.32  ? 812 CLR B C20 1 
HETATM 7060 C C21 . CLR N  2 .   ? 160.613 201.150 178.822 1.00 85.04  ? 812 CLR B C21 1 
HETATM 7061 C C22 . CLR N  2 .   ? 162.914 200.633 177.914 1.00 85.20  ? 812 CLR B C22 1 
HETATM 7062 C C23 . CLR N  2 .   ? 163.367 201.622 178.982 1.00 86.12  ? 812 CLR B C23 1 
HETATM 7063 C C24 . CLR N  2 .   ? 164.552 201.096 179.784 1.00 85.19  ? 812 CLR B C24 1 
HETATM 7064 C C25 . CLR N  2 .   ? 164.253 200.788 181.252 1.00 83.88  ? 812 CLR B C25 1 
HETATM 7065 C C26 . CLR N  2 .   ? 163.308 199.596 181.364 1.00 85.22  ? 812 CLR B C26 1 
HETATM 7066 C C27 . CLR N  2 .   ? 163.665 201.992 181.981 1.00 81.90  ? 812 CLR B C27 1 
HETATM 7067 O O1  . CLR N  2 .   ? 154.198 201.951 168.992 1.00 92.73  ? 812 CLR B O1  1 
HETATM 7068 C C1  . ACD O  6 .   ? 181.722 208.367 162.971 1.00 67.94  ? 813 ACD B C1  1 
HETATM 7069 C C2  . ACD O  6 .   ? 183.075 208.370 163.705 1.00 68.02  ? 813 ACD B C2  1 
HETATM 7070 C C3  . ACD O  6 .   ? 183.386 209.606 164.532 1.00 68.92  ? 813 ACD B C3  1 
HETATM 7071 C C4  . ACD O  6 .   ? 182.819 209.523 165.952 1.00 66.38  ? 813 ACD B C4  1 
HETATM 7072 C C5  . ACD O  6 .   ? 183.883 209.255 166.970 1.00 66.40  ? 813 ACD B C5  1 
HETATM 7073 C C6  . ACD O  6 .   ? 183.929 208.288 167.885 1.00 67.29  ? 813 ACD B C6  1 
HETATM 7074 C C7  . ACD O  6 .   ? 185.012 208.040 168.896 1.00 64.36  ? 813 ACD B C7  1 
HETATM 7075 C C8  . ACD O  6 .   ? 184.492 208.198 170.296 1.00 62.99  ? 813 ACD B C8  1 
HETATM 7076 C C9  . ACD O  6 .   ? 185.037 208.904 171.285 1.00 66.10  ? 813 ACD B C9  1 
HETATM 7077 C C10 . ACD O  6 .   ? 184.521 209.064 172.685 1.00 64.21  ? 813 ACD B C10 1 
HETATM 7078 C C11 . ACD O  6 .   ? 185.655 209.106 173.668 1.00 63.56  ? 813 ACD B C11 1 
HETATM 7079 C C12 . ACD O  6 .   ? 185.734 208.479 174.840 1.00 62.95  ? 813 ACD B C12 1 
HETATM 7080 C C13 . ACD O  6 .   ? 184.700 207.582 175.453 1.00 67.58  ? 813 ACD B C13 1 
HETATM 7081 C C14 . ACD O  6 .   ? 184.886 207.496 176.942 1.00 65.24  ? 813 ACD B C14 1 
HETATM 7082 C C15 . ACD O  6 .   ? 185.960 207.824 177.658 1.00 62.83  ? 813 ACD B C15 1 
HETATM 7083 C C16 . ACD O  6 .   ? 186.133 207.731 179.141 1.00 63.46  ? 813 ACD B C16 1 
HETATM 7084 C C17 . ACD O  6 .   ? 186.684 209.023 179.746 1.00 63.61  ? 813 ACD B C17 1 
HETATM 7085 C C18 . ACD O  6 .   ? 186.806 208.959 181.262 1.00 62.81  ? 813 ACD B C18 1 
HETATM 7086 C C19 . ACD O  6 .   ? 187.310 210.258 181.880 1.00 66.41  ? 813 ACD B C19 1 
HETATM 7087 C C20 . ACD O  6 .   ? 187.423 210.185 183.396 1.00 62.63  ? 813 ACD B C20 1 
HETATM 7088 O O1  . ACD O  6 .   ? 181.285 207.276 162.557 1.00 70.09  ? 813 ACD B O1  1 
HETATM 7089 O O2  . ACD O  6 .   ? 181.166 209.479 162.846 1.00 66.88  ? 813 ACD B O2  1 
HETATM 7090 P P   . 3PE P  3 .   ? 194.428 192.758 162.123 1.00 101.91 ? 814 3PE B P   1 
HETATM 7091 N N   . 3PE P  3 .   ? 189.422 193.105 161.592 1.00 74.53  ? 814 3PE B N   1 
HETATM 7092 O O11 . 3PE P  3 .   ? 194.554 192.671 163.759 1.00 81.05  ? 814 3PE B O11 1 
HETATM 7093 O O12 . 3PE P  3 .   ? 195.474 193.735 161.705 1.00 77.64  ? 814 3PE B O12 1 
HETATM 7094 O O13 . 3PE P  3 .   ? 192.930 193.437 161.947 1.00 82.02  ? 814 3PE B O13 1 
HETATM 7095 O O14 . 3PE P  3 .   ? 194.295 191.387 161.551 1.00 78.12  ? 814 3PE B O14 1 
HETATM 7096 C C11 . 3PE P  3 .   ? 191.857 192.655 161.480 1.00 73.88  ? 814 3PE B C11 1 
HETATM 7097 C C12 . 3PE P  3 .   ? 190.732 193.583 161.081 1.00 73.26  ? 814 3PE B C12 1 
HETATM 7098 C C1  . 3PE P  3 .   ? 194.603 191.407 164.377 1.00 71.58  ? 814 3PE B C1  1 
HETATM 7099 C C2  . 3PE P  3 .   ? 194.303 191.580 165.860 1.00 72.92  ? 814 3PE B C2  1 
HETATM 7100 C C3  . 3PE P  3 .   ? 193.171 190.678 166.301 1.00 73.16  ? 814 3PE B C3  1 
HETATM 7101 O O31 . 3PE P  3 .   ? 192.065 190.969 165.450 1.00 79.13  ? 814 3PE B O31 1 
HETATM 7102 O O32 . 3PE P  3 .   ? 190.037 190.051 165.324 1.00 77.59  ? 814 3PE B O32 1 
HETATM 7103 C C31 . 3PE P  3 .   ? 190.833 190.748 165.901 1.00 78.19  ? 814 3PE B C31 1 
HETATM 7104 C C32 . 3PE P  3 .   ? 190.586 191.472 167.196 1.00 75.03  ? 814 3PE B C32 1 
HETATM 7105 C C33 . 3PE P  3 .   ? 189.221 191.201 167.806 1.00 73.17  ? 814 3PE B C33 1 
HETATM 7106 C C34 . 3PE P  3 .   ? 189.242 191.394 169.317 1.00 69.00  ? 814 3PE B C34 1 
HETATM 7107 C C35 . 3PE P  3 .   ? 190.456 190.758 169.977 1.00 68.03  ? 814 3PE B C35 1 
HETATM 7108 C C36 . 3PE P  3 .   ? 190.284 190.589 171.479 1.00 67.44  ? 814 3PE B C36 1 
HETATM 7109 C C37 . 3PE P  3 .   ? 191.481 189.937 172.157 1.00 67.30  ? 814 3PE B C37 1 
HETATM 7110 C C38 . 3PE P  3 .   ? 191.268 189.749 173.651 1.00 68.28  ? 814 3PE B C38 1 
HETATM 7111 C C39 . 3PE P  3 .   ? 192.561 189.731 174.453 1.00 69.48  ? 814 3PE B C39 1 
HETATM 7112 C C3A . 3PE P  3 .   ? 192.363 190.243 175.872 1.00 63.28  ? 814 3PE B C3A 1 
HETATM 7113 C C3B . 3PE P  3 .   ? 193.658 190.592 176.590 1.00 66.77  ? 814 3PE B C3B 1 
HETATM 7114 C C3C . 3PE P  3 .   ? 193.395 191.238 177.941 1.00 70.13  ? 814 3PE B C3C 1 
HETATM 7115 C C3D . 3PE P  3 .   ? 194.574 191.184 178.900 1.00 69.19  ? 814 3PE B C3D 1 
HETATM 7116 C C3E . 3PE P  3 .   ? 194.154 191.456 180.336 1.00 64.04  ? 814 3PE B C3E 1 
HETATM 7117 C C3F . 3PE P  3 .   ? 195.311 191.506 181.321 1.00 63.14  ? 814 3PE B C3F 1 
HETATM 7118 C C3G . 3PE P  3 .   ? 194.832 191.594 182.761 1.00 66.06  ? 814 3PE B C3G 1 
HETATM 7119 C C3H . 3PE P  3 .   ? 195.844 192.242 183.693 1.00 73.60  ? 814 3PE B C3H 1 
HETATM 7120 C C3I . 3PE P  3 .   ? 196.356 193.574 183.166 1.00 76.76  ? 814 3PE B C3I 1 
HETATM 7121 O O21 . 3PE P  3 .   ? 195.419 191.222 166.683 1.00 79.26  ? 814 3PE B O21 1 
HETATM 7122 O O22 . 3PE P  3 .   ? 197.019 192.768 166.752 1.00 77.19  ? 814 3PE B O22 1 
HETATM 7123 C C21 . 3PE P  3 .   ? 196.131 192.145 167.294 1.00 77.97  ? 814 3PE B C21 1 
HETATM 7124 C C22 . 3PE P  3 .   ? 195.703 192.312 168.723 1.00 74.10  ? 814 3PE B C22 1 
HETATM 7125 C C23 . 3PE P  3 .   ? 195.311 191.010 169.397 1.00 74.36  ? 814 3PE B C23 1 
HETATM 7126 C C24 . 3PE P  3 .   ? 195.079 191.198 170.888 1.00 70.18  ? 814 3PE B C24 1 
HETATM 7127 C C25 . 3PE P  3 .   ? 196.305 190.882 171.732 1.00 68.92  ? 814 3PE B C25 1 
HETATM 7128 C C26 . 3PE P  3 .   ? 195.941 190.215 173.051 1.00 71.91  ? 814 3PE B C26 1 
HETATM 7129 C C27 . 3PE P  3 .   ? 197.102 189.476 173.699 1.00 70.81  ? 814 3PE B C27 1 
HETATM 7130 C C28 . 3PE P  3 .   ? 198.240 190.407 174.091 1.00 71.84  ? 814 3PE B C28 1 
HETATM 7131 C C29 . 3PE P  3 .   ? 199.516 189.678 174.483 1.00 68.03  ? 814 3PE B C29 1 
HETATM 7132 C C2A . 3PE P  3 .   ? 200.675 190.630 174.748 1.00 67.43  ? 814 3PE B C2A 1 
HETATM 7133 C C2B . 3PE P  3 .   ? 201.991 189.913 175.007 1.00 70.07  ? 814 3PE B C2B 1 
HETATM 7134 C C2C . 3PE P  3 .   ? 201.817 188.668 175.866 1.00 75.01  ? 814 3PE B C2C 1 
HETATM 7135 C C2D . 3PE P  3 .   ? 203.122 187.946 176.171 1.00 73.81  ? 814 3PE B C2D 1 
HETATM 7136 C C2E . 3PE P  3 .   ? 203.556 188.111 177.620 1.00 71.04  ? 814 3PE B C2E 1 
HETATM 7137 C C2F . 3PE P  3 .   ? 204.338 186.919 178.152 1.00 69.91  ? 814 3PE B C2F 1 
HETATM 7138 C C2G . 3PE P  3 .   ? 204.545 186.989 179.656 1.00 72.48  ? 814 3PE B C2G 1 
HETATM 7139 C C2H . 3PE P  3 .   ? 205.318 185.801 180.210 1.00 78.01  ? 814 3PE B C2H 1 
HETATM 7140 C C2I . 3PE P  3 .   ? 205.458 185.852 181.724 1.00 74.61  ? 814 3PE B C2I 1 
HETATM 7141 C C1  . CLR Q  2 .   ? 185.806 168.324 200.662 1.00 52.67  ? 801 CLR A C1  1 
HETATM 7142 C C2  . CLR Q  2 .   ? 186.110 169.240 201.842 1.00 57.75  ? 801 CLR A C2  1 
HETATM 7143 C C3  . CLR Q  2 .   ? 186.845 168.487 202.932 1.00 52.75  ? 801 CLR A C3  1 
HETATM 7144 C C4  . CLR Q  2 .   ? 188.117 167.875 202.355 1.00 54.49  ? 801 CLR A C4  1 
HETATM 7145 C C5  . CLR Q  2 .   ? 187.836 167.023 201.147 1.00 52.61  ? 801 CLR A C5  1 
HETATM 7146 C C6  . CLR Q  2 .   ? 188.007 165.706 201.219 1.00 46.94  ? 801 CLR A C6  1 
HETATM 7147 C C7  . CLR Q  2 .   ? 187.835 164.770 200.075 1.00 44.30  ? 801 CLR A C7  1 
HETATM 7148 C C8  . CLR Q  2 .   ? 187.610 165.505 198.762 1.00 46.79  ? 801 CLR A C8  1 
HETATM 7149 C C9  . CLR Q  2 .   ? 186.614 166.656 198.956 1.00 48.45  ? 801 CLR A C9  1 
HETATM 7150 C C10 . CLR Q  2 .   ? 187.059 167.691 200.026 1.00 48.73  ? 801 CLR A C10 1 
HETATM 7151 C C11 . CLR Q  2 .   ? 186.260 167.288 197.606 1.00 46.06  ? 801 CLR A C11 1 
HETATM 7152 C C12 . CLR Q  2 .   ? 185.794 166.279 196.552 1.00 47.83  ? 801 CLR A C12 1 
HETATM 7153 C C13 . CLR Q  2 .   ? 186.808 165.153 196.333 1.00 42.65  ? 801 CLR A C13 1 
HETATM 7154 C C14 . CLR Q  2 .   ? 187.066 164.546 197.720 1.00 41.34  ? 801 CLR A C14 1 
HETATM 7155 C C15 . CLR Q  2 .   ? 187.847 163.273 197.441 1.00 42.81  ? 801 CLR A C15 1 
HETATM 7156 C C16 . CLR Q  2 .   ? 187.252 162.774 196.113 1.00 41.06  ? 801 CLR A C16 1 
HETATM 7157 C C17 . CLR Q  2 .   ? 186.324 163.892 195.570 1.00 42.96  ? 801 CLR A C17 1 
HETATM 7158 C C18 . CLR Q  2 .   ? 188.086 165.687 195.685 1.00 50.83  ? 801 CLR A C18 1 
HETATM 7159 C C19 . CLR Q  2 .   ? 187.921 168.806 199.421 1.00 45.14  ? 801 CLR A C19 1 
HETATM 7160 C C20 . CLR Q  2 .   ? 186.292 163.883 194.034 1.00 49.18  ? 801 CLR A C20 1 
HETATM 7161 C C21 . CLR Q  2 .   ? 185.165 164.723 193.438 1.00 47.09  ? 801 CLR A C21 1 
HETATM 7162 C C22 . CLR Q  2 .   ? 186.229 162.431 193.532 1.00 50.12  ? 801 CLR A C22 1 
HETATM 7163 C C23 . CLR Q  2 .   ? 185.022 162.042 192.682 1.00 52.12  ? 801 CLR A C23 1 
HETATM 7164 C C24 . CLR Q  2 .   ? 185.370 161.912 191.203 1.00 49.55  ? 801 CLR A C24 1 
HETATM 7165 C C25 . CLR Q  2 .   ? 185.617 160.487 190.708 1.00 52.12  ? 801 CLR A C25 1 
HETATM 7166 C C26 . CLR Q  2 .   ? 184.375 159.625 190.914 1.00 52.02  ? 801 CLR A C26 1 
HETATM 7167 C C27 . CLR Q  2 .   ? 186.051 160.453 189.246 1.00 51.89  ? 801 CLR A C27 1 
HETATM 7168 O O1  . CLR Q  2 .   ? 187.120 169.377 203.993 1.00 50.21  ? 801 CLR A O1  1 
HETATM 7169 P P   . 3PE R  3 .   ? 207.256 178.679 204.580 1.00 86.38  ? 802 3PE A P   1 
HETATM 7170 N N   . 3PE R  3 .   ? 210.995 179.380 206.961 1.00 68.19  ? 802 3PE A N   1 
HETATM 7171 O O11 . 3PE R  3 .   ? 206.644 177.834 203.310 1.00 71.06  ? 802 3PE A O11 1 
HETATM 7172 O O12 . 3PE R  3 .   ? 207.515 180.051 204.060 1.00 74.08  ? 802 3PE A O12 1 
HETATM 7173 O O13 . 3PE R  3 .   ? 208.691 177.901 204.839 1.00 78.59  ? 802 3PE A O13 1 
HETATM 7174 O O14 . 3PE R  3 .   ? 206.452 178.397 205.804 1.00 68.75  ? 802 3PE A O14 1 
HETATM 7175 C C11 . 3PE R  3 .   ? 209.233 177.852 206.137 1.00 70.97  ? 802 3PE A C11 1 
HETATM 7176 C C12 . 3PE R  3 .   ? 209.569 179.261 206.566 1.00 70.42  ? 802 3PE A C12 1 
HETATM 7177 C C1  . 3PE R  3 .   ? 205.547 176.989 203.563 1.00 72.23  ? 802 3PE A C1  1 
HETATM 7178 C C2  . 3PE R  3 .   ? 205.201 176.156 202.336 1.00 71.87  ? 802 3PE A C2  1 
HETATM 7179 C C3  . 3PE R  3 .   ? 203.878 175.459 202.575 1.00 72.85  ? 802 3PE A C3  1 
HETATM 7180 O O31 . 3PE R  3 .   ? 203.927 174.188 201.934 1.00 66.61  ? 802 3PE A O31 1 
HETATM 7181 O O32 . 3PE R  3 .   ? 201.705 174.001 202.026 1.00 62.65  ? 802 3PE A O32 1 
HETATM 7182 C C31 . 3PE R  3 .   ? 202.773 173.584 201.661 1.00 67.77  ? 802 3PE A C31 1 
HETATM 7183 C C32 . 3PE R  3 .   ? 202.988 172.342 200.847 1.00 68.83  ? 802 3PE A C32 1 
HETATM 7184 C C33 . 3PE R  3 .   ? 203.334 172.614 199.394 1.00 73.78  ? 802 3PE A C33 1 
HETATM 7185 C C34 . 3PE R  3 .   ? 204.838 172.616 199.155 1.00 64.65  ? 802 3PE A C34 1 
HETATM 7186 C C35 . 3PE R  3 .   ? 205.210 172.481 197.685 1.00 57.01  ? 802 3PE A C35 1 
HETATM 7187 C C36 . 3PE R  3 .   ? 204.553 173.545 196.821 1.00 60.77  ? 802 3PE A C36 1 
HETATM 7188 C C37 . 3PE R  3 .   ? 204.527 173.199 195.338 1.00 67.94  ? 802 3PE A C37 1 
HETATM 7189 C C38 . 3PE R  3 .   ? 205.863 172.671 194.835 1.00 69.83  ? 802 3PE A C38 1 
HETATM 7190 C C39 . 3PE R  3 .   ? 206.281 173.249 193.490 1.00 70.04  ? 802 3PE A C39 1 
HETATM 7191 C C3A . 3PE R  3 .   ? 205.628 172.534 192.316 1.00 66.57  ? 802 3PE A C3A 1 
HETATM 7192 C C3B . 3PE R  3 .   ? 206.554 171.551 191.617 1.00 70.26  ? 802 3PE A C3B 1 
HETATM 7193 C C3C . 3PE R  3 .   ? 207.802 172.226 191.065 1.00 72.55  ? 802 3PE A C3C 1 
HETATM 7194 C C3D . 3PE R  3 .   ? 208.632 171.332 190.154 1.00 71.05  ? 802 3PE A C3D 1 
HETATM 7195 C C3E . 3PE R  3 .   ? 207.898 170.934 188.881 1.00 71.86  ? 802 3PE A C3E 1 
HETATM 7196 C C3F . 3PE R  3 .   ? 208.814 170.341 187.821 1.00 73.91  ? 802 3PE A C3F 1 
HETATM 7197 C C3G . 3PE R  3 .   ? 210.090 171.148 187.631 1.00 72.46  ? 802 3PE A C3G 1 
HETATM 7198 C C3H . 3PE R  3 .   ? 210.899 170.742 186.406 1.00 68.41  ? 802 3PE A C3H 1 
HETATM 7199 C C3I . 3PE R  3 .   ? 212.224 171.483 186.309 1.00 69.72  ? 802 3PE A C3I 1 
HETATM 7200 O O21 . 3PE R  3 .   ? 205.025 176.959 201.158 1.00 73.50  ? 802 3PE A O21 1 
HETATM 7201 O O22 . 3PE R  3 .   ? 204.016 175.763 199.559 1.00 80.41  ? 802 3PE A O22 1 
HETATM 7202 C C21 . 3PE R  3 .   ? 204.934 176.454 199.942 1.00 72.92  ? 802 3PE A C21 1 
HETATM 7203 C C22 . 3PE R  3 .   ? 206.087 176.852 199.070 1.00 67.32  ? 802 3PE A C22 1 
HETATM 7204 C C23 . 3PE R  3 .   ? 205.715 176.937 197.600 1.00 63.87  ? 802 3PE A C23 1 
HETATM 7205 C C24 . 3PE R  3 .   ? 206.578 177.946 196.857 1.00 69.09  ? 802 3PE A C24 1 
HETATM 7206 C C25 . 3PE R  3 .   ? 205.796 178.745 195.826 1.00 68.27  ? 802 3PE A C25 1 
HETATM 7207 C C26 . 3PE R  3 .   ? 205.113 177.856 194.798 1.00 67.94  ? 802 3PE A C26 1 
HETATM 7208 C C27 . 3PE R  3 .   ? 205.994 177.505 193.608 1.00 63.22  ? 802 3PE A C27 1 
HETATM 7209 C C28 . 3PE R  3 .   ? 206.316 178.713 192.739 1.00 61.95  ? 802 3PE A C28 1 
HETATM 7210 C C29 . 3PE R  3 .   ? 206.102 178.466 191.252 1.00 60.32  ? 802 3PE A C29 1 
HETATM 7211 C C2A . 3PE R  3 .   ? 206.944 177.321 190.703 1.00 64.51  ? 802 3PE A C2A 1 
HETATM 7212 C C2B . 3PE R  3 .   ? 207.302 177.495 189.234 1.00 70.07  ? 802 3PE A C2B 1 
HETATM 7213 C C2C . 3PE R  3 .   ? 208.170 176.374 188.675 1.00 72.32  ? 802 3PE A C2C 1 
HETATM 7214 C C2D . 3PE R  3 .   ? 208.645 176.649 187.254 1.00 68.84  ? 802 3PE A C2D 1 
HETATM 7215 C C2E . 3PE R  3 .   ? 208.869 175.394 186.420 1.00 64.30  ? 802 3PE A C2E 1 
HETATM 7216 C C2F . 3PE R  3 .   ? 209.085 175.701 184.943 1.00 67.09  ? 802 3PE A C2F 1 
HETATM 7217 C C2G . 3PE R  3 .   ? 209.067 174.470 184.047 1.00 67.41  ? 802 3PE A C2G 1 
HETATM 7218 C C2H . 3PE R  3 .   ? 207.670 174.063 183.597 1.00 65.04  ? 802 3PE A C2H 1 
HETATM 7219 C C2I . 3PE R  3 .   ? 207.686 173.161 182.371 1.00 59.99  ? 802 3PE A C2I 1 
HETATM 7220 C C1  . CLR S  2 .   ? 218.410 152.052 175.541 1.00 74.88  ? 803 CLR A C1  1 
HETATM 7221 C C2  . CLR S  2 .   ? 218.486 152.127 174.020 1.00 73.22  ? 803 CLR A C2  1 
HETATM 7222 C C3  . CLR S  2 .   ? 217.164 151.738 173.388 1.00 76.09  ? 803 CLR A C3  1 
HETATM 7223 C C4  . CLR S  2 .   ? 216.036 152.600 173.946 1.00 73.52  ? 803 CLR A C4  1 
HETATM 7224 C C5  . CLR S  2 .   ? 215.988 152.552 175.448 1.00 76.39  ? 803 CLR A C5  1 
HETATM 7225 C C6  . CLR S  2 .   ? 214.991 151.915 176.053 1.00 77.76  ? 803 CLR A C6  1 
HETATM 7226 C C7  . CLR S  2 .   ? 214.795 151.881 177.528 1.00 76.96  ? 803 CLR A C7  1 
HETATM 7227 C C8  . CLR S  2 .   ? 215.768 152.802 178.249 1.00 68.51  ? 803 CLR A C8  1 
HETATM 7228 C C9  . CLR S  2 .   ? 217.182 152.604 177.682 1.00 72.73  ? 803 CLR A C9  1 
HETATM 7229 C C10 . CLR S  2 .   ? 217.282 152.906 176.161 1.00 77.76  ? 803 CLR A C10 1 
HETATM 7230 C C11 . CLR S  2 .   ? 218.221 153.372 178.507 1.00 73.21  ? 803 CLR A C11 1 
HETATM 7231 C C12 . CLR S  2 .   ? 218.114 153.153 180.018 1.00 74.14  ? 803 CLR A C12 1 
HETATM 7232 C C13 . CLR S  2 .   ? 216.703 153.437 180.545 1.00 69.98  ? 803 CLR A C13 1 
HETATM 7233 C C14 . CLR S  2 .   ? 215.763 152.533 179.743 1.00 64.99  ? 803 CLR A C14 1 
HETATM 7234 C C15 . CLR S  2 .   ? 214.451 152.684 180.489 1.00 72.62  ? 803 CLR A C15 1 
HETATM 7235 C C16 . CLR S  2 .   ? 214.879 152.646 181.966 1.00 72.44  ? 803 CLR A C16 1 
HETATM 7236 C C17 . CLR S  2 .   ? 216.391 152.999 182.006 1.00 69.73  ? 803 CLR A C17 1 
HETATM 7237 C C18 . CLR S  2 .   ? 216.300 154.894 180.324 1.00 77.77  ? 803 CLR A C18 1 
HETATM 7238 C C19 . CLR S  2 .   ? 217.574 154.389 175.900 1.00 74.44  ? 803 CLR A C19 1 
HETATM 7239 C C20 . CLR S  2 .   ? 216.713 153.931 183.187 1.00 68.68  ? 803 CLR A C20 1 
HETATM 7240 C C21 . CLR S  2 .   ? 218.201 154.213 183.370 1.00 70.72  ? 803 CLR A C21 1 
HETATM 7241 C C22 . CLR S  2 .   ? 216.143 153.328 184.477 1.00 71.39  ? 803 CLR A C22 1 
HETATM 7242 C C23 . CLR S  2 .   ? 216.976 152.200 185.075 1.00 81.05  ? 803 CLR A C23 1 
HETATM 7243 C C24 . CLR S  2 .   ? 216.954 152.212 186.600 1.00 76.66  ? 803 CLR A C24 1 
HETATM 7244 C C25 . CLR S  2 .   ? 217.901 151.212 187.270 1.00 73.20  ? 803 CLR A C25 1 
HETATM 7245 C C26 . CLR S  2 .   ? 219.350 151.540 186.924 1.00 75.27  ? 803 CLR A C26 1 
HETATM 7246 C C27 . CLR S  2 .   ? 217.720 151.152 188.784 1.00 73.16  ? 803 CLR A C27 1 
HETATM 7247 O O1  . CLR S  2 .   ? 217.286 151.888 171.990 1.00 77.39  ? 803 CLR A O1  1 
HETATM 7248 C C1  . CLR T  2 .   ? 202.287 196.492 168.381 1.00 91.16  ? 804 CLR A C1  1 
HETATM 7249 C C2  . CLR T  2 .   ? 202.759 196.790 166.963 1.00 92.87  ? 804 CLR A C2  1 
HETATM 7250 C C3  . CLR T  2 .   ? 201.934 196.010 165.961 1.00 92.47  ? 804 CLR A C3  1 
HETATM 7251 C C4  . CLR T  2 .   ? 200.467 196.396 166.113 1.00 89.86  ? 804 CLR A C4  1 
HETATM 7252 C C5  . CLR T  2 .   ? 199.972 196.172 167.517 1.00 90.23  ? 804 CLR A C5  1 
HETATM 7253 C C6  . CLR T  2 .   ? 198.842 195.499 167.725 1.00 88.24  ? 804 CLR A C6  1 
HETATM 7254 C C7  . CLR T  2 .   ? 198.295 195.144 169.066 1.00 87.83  ? 804 CLR A C7  1 
HETATM 7255 C C8  . CLR T  2 .   ? 198.900 195.966 170.197 1.00 90.54  ? 804 CLR A C8  1 
HETATM 7256 C C9  . CLR T  2 .   ? 200.414 196.125 170.001 1.00 86.76  ? 804 CLR A C9  1 
HETATM 7257 C C10 . CLR T  2 .   ? 200.792 196.777 168.645 1.00 90.38  ? 804 CLR A C10 1 
HETATM 7258 C C11 . CLR T  2 .   ? 201.048 196.820 171.211 1.00 84.21  ? 804 CLR A C11 1 
HETATM 7259 C C12 . CLR T  2 .   ? 200.706 196.159 172.549 1.00 86.72  ? 804 CLR A C12 1 
HETATM 7260 C C13 . CLR T  2 .   ? 199.196 196.021 172.761 1.00 89.72  ? 804 CLR A C13 1 
HETATM 7261 C C14 . CLR T  2 .   ? 198.644 195.285 171.529 1.00 90.48  ? 804 CLR A C14 1 
HETATM 7262 C C15 . CLR T  2 .   ? 197.209 194.942 171.903 1.00 88.54  ? 804 CLR A C15 1 
HETATM 7263 C C16 . CLR T  2 .   ? 197.288 194.676 173.417 1.00 87.64  ? 804 CLR A C16 1 
HETATM 7264 C C17 . CLR T  2 .   ? 198.726 195.047 173.873 1.00 87.98  ? 804 CLR A C17 1 
HETATM 7265 C C18 . CLR T  2 .   ? 198.540 197.391 172.955 1.00 86.86  ? 804 CLR A C18 1 
HETATM 7266 C C19 . CLR T  2 .   ? 200.556 198.294 168.654 1.00 88.70  ? 804 CLR A C19 1 
HETATM 7267 C C20 . CLR T  2 .   ? 198.782 195.488 175.345 1.00 87.02  ? 804 CLR A C20 1 
HETATM 7268 C C21 . CLR T  2 .   ? 200.151 195.279 175.987 1.00 85.98  ? 804 CLR A C21 1 
HETATM 7269 C C22 . CLR T  2 .   ? 197.701 194.763 176.162 1.00 86.17  ? 804 CLR A C22 1 
HETATM 7270 C C23 . CLR T  2 .   ? 198.097 193.396 176.708 1.00 85.32  ? 804 CLR A C23 1 
HETATM 7271 C C24 . CLR T  2 .   ? 197.490 193.121 178.079 1.00 87.63  ? 804 CLR A C24 1 
HETATM 7272 C C25 . CLR T  2 .   ? 198.467 193.191 179.254 1.00 89.57  ? 804 CLR A C25 1 
HETATM 7273 C C26 . CLR T  2 .   ? 198.685 194.639 179.684 1.00 88.70  ? 804 CLR A C26 1 
HETATM 7274 C C27 . CLR T  2 .   ? 199.805 192.534 178.932 1.00 89.68  ? 804 CLR A C27 1 
HETATM 7275 O O1  . CLR T  2 .   ? 202.426 196.276 164.663 1.00 92.00  ? 804 CLR A O1  1 
HETATM 7276 C C1  . CLR U  2 .   ? 196.112 145.058 173.370 1.00 89.83  ? 805 CLR A C1  1 
HETATM 7277 C C2  . CLR U  2 .   ? 196.310 145.235 171.869 1.00 89.66  ? 805 CLR A C2  1 
HETATM 7278 C C3  . CLR U  2 .   ? 195.128 144.685 171.097 1.00 90.69  ? 805 CLR A C3  1 
HETATM 7279 C C4  . CLR U  2 .   ? 193.833 145.324 171.592 1.00 91.35  ? 805 CLR A C4  1 
HETATM 7280 C C5  . CLR U  2 .   ? 193.673 145.211 173.085 1.00 90.22  ? 805 CLR A C5  1 
HETATM 7281 C C6  . CLR U  2 .   ? 192.665 144.507 173.597 1.00 89.68  ? 805 CLR A C6  1 
HETATM 7282 C C7  . CLR U  2 .   ? 192.383 144.381 175.054 1.00 91.17  ? 805 CLR A C7  1 
HETATM 7283 C C8  . CLR U  2 .   ? 193.207 145.366 175.872 1.00 89.99  ? 805 CLR A C8  1 
HETATM 7284 C C9  . CLR U  2 .   ? 194.672 145.333 175.414 1.00 91.09  ? 805 CLR A C9  1 
HETATM 7285 C C10 . CLR U  2 .   ? 194.834 145.723 173.920 1.00 92.21  ? 805 CLR A C10 1 
HETATM 7286 C C11 . CLR U  2 .   ? 195.570 146.147 176.358 1.00 90.74  ? 805 CLR A C11 1 
HETATM 7287 C C12 . CLR U  2 .   ? 195.353 145.892 177.855 1.00 84.90  ? 805 CLR A C12 1 
HETATM 7288 C C13 . CLR U  2 .   ? 193.881 146.029 178.251 1.00 87.86  ? 805 CLR A C13 1 
HETATM 7289 C C14 . CLR U  2 .   ? 193.141 145.031 177.349 1.00 87.55  ? 805 CLR A C14 1 
HETATM 7290 C C15 . CLR U  2 .   ? 191.782 144.856 178.002 1.00 89.90  ? 805 CLR A C15 1 
HETATM 7291 C C16 . CLR U  2 .   ? 192.174 144.736 179.483 1.00 91.35  ? 805 CLR A C16 1 
HETATM 7292 C C17 . CLR U  2 .   ? 193.487 145.548 179.677 1.00 87.01  ? 805 CLR A C17 1 
HETATM 7293 C C18 . CLR U  2 .   ? 193.393 147.466 178.039 1.00 93.39  ? 805 CLR A C18 1 
HETATM 7294 C C19 . CLR U  2 .   ? 194.926 147.245 173.735 1.00 89.95  ? 805 CLR A C19 1 
HETATM 7295 C C20 . CLR U  2 .   ? 193.349 146.595 180.796 1.00 86.96  ? 805 CLR A C20 1 
HETATM 7296 C C21 . CLR U  2 .   ? 194.674 146.925 181.480 1.00 88.89  ? 805 CLR A C21 1 
HETATM 7297 C C22 . CLR U  2 .   ? 192.287 146.157 181.819 1.00 85.84  ? 805 CLR A C22 1 
HETATM 7298 C C23 . CLR U  2 .   ? 192.791 145.559 183.129 1.00 85.54  ? 805 CLR A C23 1 
HETATM 7299 C C24 . CLR U  2 .   ? 193.085 144.067 183.013 1.00 86.29  ? 805 CLR A C24 1 
HETATM 7300 C C25 . CLR U  2 .   ? 193.068 143.302 184.337 1.00 89.83  ? 805 CLR A C25 1 
HETATM 7301 C C26 . CLR U  2 .   ? 193.833 144.074 185.408 1.00 88.19  ? 805 CLR A C26 1 
HETATM 7302 C C27 . CLR U  2 .   ? 193.637 141.893 184.196 1.00 88.27  ? 805 CLR A C27 1 
HETATM 7303 O O1  . CLR U  2 .   ? 195.342 144.927 169.721 1.00 87.73  ? 805 CLR A O1  1 
HETATM 7304 P P   . 3PE V  3 .   ? 187.242 180.995 204.987 1.00 99.97  ? 806 3PE A P   1 
HETATM 7305 N N   . 3PE V  3 .   ? 191.795 182.543 206.155 1.00 75.95  ? 806 3PE A N   1 
HETATM 7306 O O11 . 3PE V  3 .   ? 187.740 181.596 203.542 1.00 78.49  ? 806 3PE A O11 1 
HETATM 7307 O O12 . 3PE V  3 .   ? 186.377 182.057 205.576 1.00 77.38  ? 806 3PE A O12 1 
HETATM 7308 O O13 . 3PE V  3 .   ? 188.674 180.924 205.811 1.00 83.90  ? 806 3PE A O13 1 
HETATM 7309 O O14 . 3PE V  3 .   ? 186.820 179.573 204.827 1.00 79.47  ? 806 3PE A O14 1 
HETATM 7310 C C11 . 3PE V  3 .   ? 189.860 181.346 205.180 1.00 76.66  ? 806 3PE A C11 1 
HETATM 7311 C C12 . 3PE V  3 .   ? 190.979 181.303 206.195 1.00 77.35  ? 806 3PE A C12 1 
HETATM 7312 C C1  . 3PE V  3 .   ? 186.779 181.934 202.570 1.00 74.85  ? 806 3PE A C1  1 
HETATM 7313 C C2  . 3PE V  3 .   ? 187.178 181.279 201.256 1.00 71.22  ? 806 3PE A C2  1 
HETATM 7314 C C3  . 3PE V  3 .   ? 187.650 182.300 200.242 1.00 72.91  ? 806 3PE A C3  1 
HETATM 7315 O O31 . 3PE V  3 .   ? 187.447 181.728 198.954 1.00 75.60  ? 806 3PE A O31 1 
HETATM 7316 O O32 . 3PE V  3 .   ? 189.547 182.124 198.307 1.00 66.23  ? 806 3PE A O32 1 
HETATM 7317 C C31 . 3PE V  3 .   ? 188.498 181.550 198.160 1.00 71.19  ? 806 3PE A C31 1 
HETATM 7318 C C32 . 3PE V  3 .   ? 188.183 180.545 197.088 1.00 71.59  ? 806 3PE A C32 1 
HETATM 7319 C C33 . 3PE V  3 .   ? 188.972 180.718 195.803 1.00 70.88  ? 806 3PE A C33 1 
HETATM 7320 C C34 . 3PE V  3 .   ? 188.435 179.799 194.714 1.00 70.84  ? 806 3PE A C34 1 
HETATM 7321 C C35 . 3PE V  3 .   ? 188.878 180.197 193.316 1.00 74.11  ? 806 3PE A C35 1 
HETATM 7322 C C36 . 3PE V  3 .   ? 189.640 179.091 192.601 1.00 77.52  ? 806 3PE A C36 1 
HETATM 7323 C C37 . 3PE V  3 .   ? 188.936 178.556 191.359 1.00 74.83  ? 806 3PE A C37 1 
HETATM 7324 C C38 . 3PE V  3 .   ? 188.790 179.606 190.267 1.00 72.17  ? 806 3PE A C38 1 
HETATM 7325 C C39 . 3PE V  3 .   ? 188.081 179.107 189.014 1.00 73.41  ? 806 3PE A C39 1 
HETATM 7326 C C3A . 3PE V  3 .   ? 189.039 178.546 187.971 1.00 76.77  ? 806 3PE A C3A 1 
HETATM 7327 C C3B . 3PE V  3 .   ? 188.345 178.160 186.672 1.00 77.37  ? 806 3PE A C3B 1 
HETATM 7328 C C3C . 3PE V  3 .   ? 189.296 178.031 185.491 1.00 75.75  ? 806 3PE A C3C 1 
HETATM 7329 C C3D . 3PE V  3 .   ? 188.673 178.438 184.162 1.00 75.36  ? 806 3PE A C3D 1 
HETATM 7330 C C3E . 3PE V  3 .   ? 187.211 178.030 184.034 1.00 77.57  ? 806 3PE A C3E 1 
HETATM 7331 C C3F . 3PE V  3 .   ? 186.566 178.456 182.722 1.00 79.21  ? 806 3PE A C3F 1 
HETATM 7332 C C3G . 3PE V  3 .   ? 187.065 177.659 181.525 1.00 76.94  ? 806 3PE A C3G 1 
HETATM 7333 C C3H . 3PE V  3 .   ? 186.569 178.181 180.182 1.00 71.80  ? 806 3PE A C3H 1 
HETATM 7334 C C3I . 3PE V  3 .   ? 185.068 178.019 179.999 1.00 72.54  ? 806 3PE A C3I 1 
HETATM 7335 O O21 . 3PE V  3 .   ? 188.284 180.385 201.424 1.00 71.57  ? 806 3PE A O21 1 
HETATM 7336 O O22 . 3PE V  3 .   ? 189.136 179.025 199.887 1.00 85.42  ? 806 3PE A O22 1 
HETATM 7337 C C21 . 3PE V  3 .   ? 188.348 179.237 200.784 1.00 78.89  ? 806 3PE A C21 1 
HETATM 7338 C C22 . 3PE V  3 .   ? 187.356 178.243 201.317 1.00 72.41  ? 806 3PE A C22 1 
HETATM 7339 C C23 . 3PE V  3 .   ? 186.186 177.907 200.406 1.00 74.34  ? 806 3PE A C23 1 
HETATM 7340 C C24 . 3PE V  3 .   ? 186.639 177.348 199.065 1.00 73.58  ? 806 3PE A C24 1 
HETATM 7341 C C25 . 3PE V  3 .   ? 187.618 176.191 199.195 1.00 68.02  ? 806 3PE A C25 1 
HETATM 7342 C C26 . 3PE V  3 .   ? 188.234 175.804 197.859 1.00 70.86  ? 806 3PE A C26 1 
HETATM 7343 C C27 . 3PE V  3 .   ? 187.201 175.542 196.774 1.00 71.54  ? 806 3PE A C27 1 
HETATM 7344 C C28 . 3PE V  3 .   ? 187.415 176.418 195.549 1.00 72.15  ? 806 3PE A C28 1 
HETATM 7345 C C29 . 3PE V  3 .   ? 187.533 175.635 194.251 1.00 73.17  ? 806 3PE A C29 1 
HETATM 7346 C C2A . 3PE V  3 .   ? 186.253 174.895 193.887 1.00 74.90  ? 806 3PE A C2A 1 
HETATM 7347 C C2B . 3PE V  3 .   ? 186.243 174.386 192.453 1.00 73.31  ? 806 3PE A C2B 1 
HETATM 7348 C C2C . 3PE V  3 .   ? 186.726 175.426 191.451 1.00 70.12  ? 806 3PE A C2C 1 
HETATM 7349 C C2D . 3PE V  3 .   ? 186.435 175.048 190.004 1.00 72.66  ? 806 3PE A C2D 1 
HETATM 7350 C C2E . 3PE V  3 .   ? 186.825 173.615 189.667 1.00 76.44  ? 806 3PE A C2E 1 
HETATM 7351 C C2F . 3PE V  3 .   ? 186.510 173.227 188.227 1.00 77.76  ? 806 3PE A C2F 1 
HETATM 7352 C C2G . 3PE V  3 .   ? 185.165 173.753 187.742 1.00 77.09  ? 806 3PE A C2G 1 
HETATM 7353 C C2H . 3PE V  3 .   ? 184.586 172.956 186.580 1.00 76.26  ? 806 3PE A C2H 1 
HETATM 7354 C C2I . 3PE V  3 .   ? 184.145 171.558 186.988 1.00 73.49  ? 806 3PE A C2I 1 
HETATM 7355 C C1  . CLR W  2 .   ? 200.457 143.049 203.324 1.00 80.70  ? 807 CLR A C1  1 
HETATM 7356 C C2  . CLR W  2 .   ? 199.920 143.418 204.702 1.00 78.68  ? 807 CLR A C2  1 
HETATM 7357 C C3  . CLR W  2 .   ? 200.517 144.729 205.175 1.00 81.32  ? 807 CLR A C3  1 
HETATM 7358 C C4  . CLR W  2 .   ? 200.220 145.829 204.161 1.00 79.64  ? 807 CLR A C4  1 
HETATM 7359 C C5  . CLR W  2 .   ? 200.671 145.462 202.772 1.00 80.59  ? 807 CLR A C5  1 
HETATM 7360 C C6  . CLR W  2 .   ? 201.291 146.359 202.008 1.00 79.01  ? 807 CLR A C6  1 
HETATM 7361 C C7  . CLR W  2 .   ? 201.648 146.159 200.573 1.00 76.19  ? 807 CLR A C7  1 
HETATM 7362 C C8  . CLR W  2 .   ? 201.018 144.912 199.963 1.00 77.52  ? 807 CLR A C8  1 
HETATM 7363 C C9  . CLR W  2 .   ? 201.039 143.763 200.979 1.00 79.26  ? 807 CLR A C9  1 
HETATM 7364 C C10 . CLR W  2 .   ? 200.213 144.118 202.239 1.00 81.04  ? 807 CLR A C10 1 
HETATM 7365 C C11 . CLR W  2 .   ? 200.642 142.428 200.341 1.00 80.20  ? 807 CLR A C11 1 
HETATM 7366 C C12 . CLR W  2 .   ? 201.429 142.100 199.070 1.00 83.63  ? 807 CLR A C12 1 
HETATM 7367 C C13 . CLR W  2 .   ? 201.298 143.215 198.032 1.00 84.07  ? 807 CLR A C13 1 
HETATM 7368 C C14 . CLR W  2 .   ? 201.772 144.511 198.708 1.00 79.17  ? 807 CLR A C14 1 
HETATM 7369 C C15 . CLR W  2 .   ? 201.858 145.521 197.572 1.00 75.13  ? 807 CLR A C15 1 
HETATM 7370 C C16 . CLR W  2 .   ? 202.230 144.661 196.350 1.00 74.38  ? 807 CLR A C16 1 
HETATM 7371 C C17 . CLR W  2 .   ? 202.296 143.193 196.848 1.00 76.17  ? 807 CLR A C17 1 
HETATM 7372 C C18 . CLR W  2 .   ? 199.859 143.319 197.518 1.00 83.27  ? 807 CLR A C18 1 
HETATM 7373 C C19 . CLR W  2 .   ? 198.713 144.209 201.924 1.00 77.49  ? 807 CLR A C19 1 
HETATM 7374 C C20 . CLR W  2 .   ? 202.148 142.149 195.727 1.00 75.51  ? 807 CLR A C20 1 
HETATM 7375 C C21 . CLR W  2 .   ? 203.439 141.363 195.502 1.00 75.81  ? 807 CLR A C21 1 
HETATM 7376 C C22 . CLR W  2 .   ? 201.636 142.804 194.430 1.00 75.16  ? 807 CLR A C22 1 
HETATM 7377 C C23 . CLR W  2 .   ? 202.597 142.895 193.247 1.00 77.11  ? 807 CLR A C23 1 
HETATM 7378 C C24 . CLR W  2 .   ? 202.344 141.814 192.200 1.00 79.51  ? 807 CLR A C24 1 
HETATM 7379 C C25 . CLR W  2 .   ? 200.889 141.631 191.763 1.00 79.91  ? 807 CLR A C25 1 
HETATM 7380 C C26 . CLR W  2 .   ? 200.368 142.885 191.070 1.00 77.64  ? 807 CLR A C26 1 
HETATM 7381 C C27 . CLR W  2 .   ? 200.715 140.421 190.850 1.00 75.64  ? 807 CLR A C27 1 
HETATM 7382 O O1  . CLR W  2 .   ? 199.982 145.033 206.446 1.00 82.57  ? 807 CLR A O1  1 
HETATM 7383 C C1  . CLR X  2 .   ? 210.448 140.801 199.867 1.00 82.01  ? 808 CLR A C1  1 
HETATM 7384 C C2  . CLR X  2 .   ? 210.591 140.789 201.384 1.00 80.68  ? 808 CLR A C2  1 
HETATM 7385 C C3  . CLR X  2 .   ? 212.053 140.783 201.790 1.00 84.37  ? 808 CLR A C3  1 
HETATM 7386 C C4  . CLR X  2 .   ? 212.793 141.959 201.152 1.00 80.14  ? 808 CLR A C4  1 
HETATM 7387 C C5  . CLR X  2 .   ? 212.578 142.040 199.663 1.00 82.28  ? 808 CLR A C5  1 
HETATM 7388 C C6  . CLR X  2 .   ? 213.572 142.395 198.848 1.00 82.17  ? 808 CLR A C6  1 
HETATM 7389 C C7  . CLR X  2 .   ? 213.405 142.757 197.408 1.00 81.61  ? 808 CLR A C7  1 
HETATM 7390 C C8  . CLR X  2 .   ? 211.946 142.976 197.019 1.00 79.98  ? 808 CLR A C8  1 
HETATM 7391 C C9  . CLR X  2 .   ? 211.086 141.880 197.665 1.00 81.78  ? 808 CLR A C9  1 
HETATM 7392 C C10 . CLR X  2 .   ? 211.134 142.012 199.205 1.00 83.10  ? 808 CLR A C10 1 
HETATM 7393 C C11 . CLR X  2 .   ? 209.662 141.841 197.102 1.00 80.00  ? 808 CLR A C11 1 
HETATM 7394 C C12 . CLR X  2 .   ? 209.596 141.876 195.575 1.00 79.32  ? 808 CLR A C12 1 
HETATM 7395 C C13 . CLR X  2 .   ? 210.317 143.108 195.027 1.00 82.75  ? 808 CLR A C13 1 
HETATM 7396 C C14 . CLR X  2 .   ? 211.771 142.991 195.509 1.00 82.57  ? 808 CLR A C14 1 
HETATM 7397 C C15 . CLR X  2 .   ? 212.521 144.045 194.706 1.00 79.45  ? 808 CLR A C15 1 
HETATM 7398 C C16 . CLR X  2 .   ? 211.785 144.077 193.352 1.00 79.96  ? 808 CLR A C16 1 
HETATM 7399 C C17 . CLR X  2 .   ? 210.523 143.183 193.493 1.00 86.67  ? 808 CLR A C17 1 
HETATM 7400 C C18 . CLR X  2 .   ? 209.645 144.390 195.521 1.00 79.75  ? 808 CLR A C18 1 
HETATM 7401 C C19 . CLR X  2 .   ? 210.465 143.306 199.677 1.00 81.67  ? 808 CLR A C19 1 
HETATM 7402 C C20 . CLR X  2 .   ? 209.358 143.656 192.608 1.00 84.35  ? 808 CLR A C20 1 
HETATM 7403 C C21 . CLR X  2 .   ? 208.378 142.537 192.260 1.00 78.10  ? 808 CLR A C21 1 
HETATM 7404 C C22 . CLR X  2 .   ? 209.883 144.340 191.335 1.00 82.27  ? 808 CLR A C22 1 
HETATM 7405 C C23 . CLR X  2 .   ? 209.896 143.494 190.066 1.00 84.25  ? 808 CLR A C23 1 
HETATM 7406 C C24 . CLR X  2 .   ? 209.123 144.150 188.925 1.00 81.43  ? 808 CLR A C24 1 
HETATM 7407 C C25 . CLR X  2 .   ? 207.629 143.824 188.871 1.00 83.02  ? 808 CLR A C25 1 
HETATM 7408 C C26 . CLR X  2 .   ? 207.420 142.317 188.753 1.00 82.01  ? 808 CLR A C26 1 
HETATM 7409 C C27 . CLR X  2 .   ? 206.927 144.530 187.715 1.00 81.05  ? 808 CLR A C27 1 
HETATM 7410 O O1  . CLR X  2 .   ? 212.119 140.826 203.201 1.00 83.62  ? 808 CLR A O1  1 
HETATM 7411 C C1  . LPE Y  4 .   ? 201.187 192.341 195.650 1.00 84.52  ? 809 LPE A C1  1 
HETATM 7412 O O1  . LPE Y  4 .   ? 201.550 192.422 194.286 1.00 84.15  ? 809 LPE A O1  1 
HETATM 7413 C C2  . LPE Y  4 .   ? 202.254 193.070 196.481 1.00 89.75  ? 809 LPE A C2  1 
HETATM 7414 O O2H . LPE Y  4 .   ? 201.635 193.812 197.483 1.00 86.86  ? 809 LPE A O2H 1 
HETATM 7415 C C3  . LPE Y  4 .   ? 203.198 192.043 197.124 1.00 88.64  ? 809 LPE A C3  1 
HETATM 7416 C C11 . LPE Y  4 .   ? 200.612 193.123 193.483 1.00 84.06  ? 809 LPE A C11 1 
HETATM 7417 C C12 . LPE Y  4 .   ? 201.034 192.980 191.997 1.00 84.76  ? 809 LPE A C12 1 
HETATM 7418 O O3  . LPE Y  4 .   ? 202.419 191.084 197.816 1.00 89.41  ? 809 LPE A O3  1 
HETATM 7419 P P   . LPE Y  4 .   ? 203.057 189.565 198.023 1.00 96.45  ? 809 LPE A P   1 
HETATM 7420 O O31 . LPE Y  4 .   ? 204.290 189.599 198.821 1.00 82.23  ? 809 LPE A O31 1 
HETATM 7421 O O32 . LPE Y  4 .   ? 202.200 188.728 198.861 1.00 89.10  ? 809 LPE A O32 1 
HETATM 7422 O O33 . LPE Y  4 .   ? 203.322 188.884 196.532 1.00 90.20  ? 809 LPE A O33 1 
HETATM 7423 C C31 . LPE Y  4 .   ? 202.236 188.806 195.627 1.00 83.03  ? 809 LPE A C31 1 
HETATM 7424 C C32 . LPE Y  4 .   ? 202.768 189.086 194.200 1.00 86.47  ? 809 LPE A C32 1 
HETATM 7425 N N   . LPE Y  4 .   ? 201.930 188.456 193.141 1.00 84.33  ? 809 LPE A N   1 
HETATM 7426 C C1N . LPE Y  4 .   ? 202.541 187.128 192.851 1.00 82.92  ? 809 LPE A C1N 1 
HETATM 7427 C C2N . LPE Y  4 .   ? 200.516 188.516 193.569 1.00 83.01  ? 809 LPE A C2N 1 
HETATM 7428 C C3N . LPE Y  4 .   ? 202.011 189.234 191.883 1.00 81.81  ? 809 LPE A C3N 1 
HETATM 7429 C C13 . LPE Y  4 .   ? 199.927 192.309 191.138 1.00 87.10  ? 809 LPE A C13 1 
HETATM 7430 C C14 . LPE Y  4 .   ? 198.591 193.102 191.175 1.00 86.09  ? 809 LPE A C14 1 
HETATM 7431 C C15 . LPE Y  4 .   ? 197.721 192.853 189.911 1.00 83.70  ? 809 LPE A C15 1 
HETATM 7432 C C16 . LPE Y  4 .   ? 198.361 193.445 188.623 1.00 83.10  ? 809 LPE A C16 1 
HETATM 7433 C C17 . LPE Y  4 .   ? 198.785 192.345 187.617 1.00 83.77  ? 809 LPE A C17 1 
HETATM 7434 C C18 . LPE Y  4 .   ? 197.568 191.639 186.951 1.00 87.13  ? 809 LPE A C18 1 
HETATM 7435 C C19 . LPE Y  4 .   ? 197.991 190.425 186.079 1.00 86.94  ? 809 LPE A C19 1 
HETATM 7436 C C20 . LPE Y  4 .   ? 199.385 190.613 185.424 1.00 85.56  ? 809 LPE A C20 1 
HETATM 7437 C C21 . LPE Y  4 .   ? 199.298 191.308 184.036 1.00 84.23  ? 809 LPE A C21 1 
HETATM 7438 C C22 . LPE Y  4 .   ? 200.675 191.842 183.552 1.00 81.57  ? 809 LPE A C22 1 
HETATM 7439 C C23 . LPE Y  4 .   ? 201.096 191.252 182.174 1.00 82.89  ? 809 LPE A C23 1 
HETATM 7440 C C24 . LPE Y  4 .   ? 202.458 191.810 181.683 1.00 82.95  ? 809 LPE A C24 1 
HETATM 7441 C C25 . LPE Y  4 .   ? 203.655 190.942 182.154 1.00 84.63  ? 809 LPE A C25 1 
HETATM 7442 C C26 . LPE Y  4 .   ? 204.258 191.438 183.490 1.00 84.44  ? 809 LPE A C26 1 
HETATM 7443 C C27 . LPE Y  4 .   ? 205.321 190.475 184.055 1.00 85.65  ? 809 LPE A C27 1 
HETATM 7444 C C28 . LPE Y  4 .   ? 206.275 189.947 182.967 1.00 84.70  ? 809 LPE A C28 1 
HETATM 7445 C C1  . PLM Z  5 .   ? 199.411 192.858 201.784 1.00 79.16  ? 810 PLM A C1  1 
HETATM 7446 O O1  . PLM Z  5 .   ? 200.139 192.897 202.811 1.00 80.27  ? 810 PLM A O1  1 
HETATM 7447 O O2  . PLM Z  5 .   ? 198.979 191.851 201.159 1.00 79.24  ? 810 PLM A O2  1 
HETATM 7448 C C2  . PLM Z  5 .   ? 198.995 194.262 201.224 1.00 76.18  ? 810 PLM A C2  1 
HETATM 7449 C C3  . PLM Z  5 .   ? 199.495 194.580 199.816 1.00 75.58  ? 810 PLM A C3  1 
HETATM 7450 C C4  . PLM Z  5 .   ? 198.582 195.522 199.018 1.00 76.19  ? 810 PLM A C4  1 
HETATM 7451 C C5  . PLM Z  5 .   ? 199.146 195.899 197.642 1.00 78.49  ? 810 PLM A C5  1 
HETATM 7452 C C6  . PLM Z  5 .   ? 198.167 196.667 196.747 1.00 74.56  ? 810 PLM A C6  1 
HETATM 7453 C C7  . PLM Z  5 .   ? 197.165 195.772 196.008 1.00 73.38  ? 810 PLM A C7  1 
HETATM 7454 C C8  . PLM Z  5 .   ? 197.550 195.477 194.556 1.00 75.16  ? 810 PLM A C8  1 
HETATM 7455 C C9  . PLM Z  5 .   ? 196.468 194.724 193.774 1.00 75.36  ? 810 PLM A C9  1 
HETATM 7456 C CA  . PLM Z  5 .   ? 195.330 195.615 193.265 1.00 76.30  ? 810 PLM A CA  1 
HETATM 7457 C CB  . PLM Z  5 .   ? 195.433 195.953 191.771 1.00 76.68  ? 810 PLM A CB  1 
HETATM 7458 C CC  . PLM Z  5 .   ? 194.149 196.553 191.179 1.00 77.93  ? 810 PLM A CC  1 
HETATM 7459 C CD  . PLM Z  5 .   ? 194.280 196.943 189.701 1.00 80.43  ? 810 PLM A CD  1 
HETATM 7460 C CE  . PLM Z  5 .   ? 194.845 195.824 188.815 1.00 81.60  ? 810 PLM A CE  1 
HETATM 7461 C CF  . PLM Z  5 .   ? 195.212 196.283 187.397 1.00 78.03  ? 810 PLM A CF  1 
HETATM 7462 C CG  . PLM Z  5 .   ? 195.767 195.157 186.517 1.00 73.57  ? 810 PLM A CG  1 
HETATM 7463 C C1  . CLR AA 2 .   ? 222.184 176.057 172.537 1.00 93.29  ? 811 CLR A C1  1 
HETATM 7464 C C2  . CLR AA 2 .   ? 223.198 176.106 171.400 1.00 92.80  ? 811 CLR A C2  1 
HETATM 7465 C C3  . CLR AA 2 .   ? 222.556 175.676 170.098 1.00 95.02  ? 811 CLR A C3  1 
HETATM 7466 C C4  . CLR AA 2 .   ? 221.369 176.585 169.793 1.00 93.02  ? 811 CLR A C4  1 
HETATM 7467 C C5  . CLR AA 2 .   ? 220.373 176.605 170.922 1.00 90.87  ? 811 CLR A C5  1 
HETATM 7468 C C6  . CLR AA 2 .   ? 219.085 176.371 170.679 1.00 88.57  ? 811 CLR A C6  1 
HETATM 7469 C C7  . CLR AA 2 .   ? 218.009 176.357 171.711 1.00 91.62  ? 811 CLR A C7  1 
HETATM 7470 C C8  . CLR AA 2 .   ? 218.447 176.963 173.039 1.00 92.28  ? 811 CLR A C8  1 
HETATM 7471 C C9  . CLR AA 2 .   ? 219.870 176.513 173.391 1.00 93.14  ? 811 CLR A C9  1 
HETATM 7472 C C10 . CLR AA 2 .   ? 220.913 176.904 172.311 1.00 93.41  ? 811 CLR A C10 1 
HETATM 7473 C C11 . CLR AA 2 .   ? 220.256 176.966 174.804 1.00 93.20  ? 811 CLR A C11 1 
HETATM 7474 C C12 . CLR AA 2 .   ? 219.238 176.574 175.879 1.00 93.53  ? 811 CLR A C12 1 
HETATM 7475 C C13 . CLR AA 2 .   ? 217.832 177.077 175.544 1.00 93.59  ? 811 CLR A C13 1 
HETATM 7476 C C14 . CLR AA 2 .   ? 217.501 176.534 174.147 1.00 92.39  ? 811 CLR A C14 1 
HETATM 7477 C C15 . CLR AA 2 .   ? 216.021 176.830 173.989 1.00 90.82  ? 811 CLR A C15 1 
HETATM 7478 C C16 . CLR AA 2 .   ? 215.465 176.470 175.377 1.00 92.07  ? 811 CLR A C16 1 
HETATM 7479 C C17 . CLR AA 2 .   ? 216.663 176.472 176.368 1.00 93.12  ? 811 CLR A C17 1 
HETATM 7480 C C18 . CLR AA 2 .   ? 217.770 178.606 175.598 1.00 86.88  ? 811 CLR A C18 1 
HETATM 7481 C C19 . CLR AA 2 .   ? 221.273 178.395 172.380 1.00 90.19  ? 811 CLR A C19 1 
HETATM 7482 C C20 . CLR AA 2 .   ? 216.302 177.100 177.724 1.00 91.94  ? 811 CLR A C20 1 
HETATM 7483 C C21 . CLR AA 2 .   ? 217.085 176.499 178.890 1.00 90.92  ? 811 CLR A C21 1 
HETATM 7484 C C22 . CLR AA 2 .   ? 214.787 177.012 177.973 1.00 89.22  ? 811 CLR A C22 1 
HETATM 7485 C C23 . CLR AA 2 .   ? 214.328 176.029 179.044 1.00 89.95  ? 811 CLR A C23 1 
HETATM 7486 C C24 . CLR AA 2 .   ? 213.137 176.561 179.833 1.00 89.40  ? 811 CLR A C24 1 
HETATM 7487 C C25 . CLR AA 2 .   ? 213.425 176.873 181.302 1.00 88.21  ? 811 CLR A C25 1 
HETATM 7488 C C26 . CLR AA 2 .   ? 214.382 178.055 181.417 1.00 90.64  ? 811 CLR A C26 1 
HETATM 7489 C C27 . CLR AA 2 .   ? 213.994 175.666 182.041 1.00 86.11  ? 811 CLR A C27 1 
HETATM 7490 O O1  . CLR AA 2 .   ? 223.532 175.719 169.078 1.00 97.99  ? 811 CLR A O1  1 
HETATM 7491 C C1  . ACD BA 6 .   ? 195.991 169.260 162.988 1.00 84.83  ? 812 ACD A C1  1 
HETATM 7492 C C2  . ACD BA 6 .   ? 194.638 169.276 163.723 1.00 84.48  ? 812 ACD A C2  1 
HETATM 7493 C C3  . ACD BA 6 .   ? 194.314 168.050 164.559 1.00 86.03  ? 812 ACD A C3  1 
HETATM 7494 C C4  . ACD BA 6 .   ? 194.876 168.141 165.981 1.00 83.06  ? 812 ACD A C4  1 
HETATM 7495 C C5  . ACD BA 6 .   ? 193.807 168.385 166.999 1.00 83.57  ? 812 ACD A C5  1 
HETATM 7496 C C6  . ACD BA 6 .   ? 193.740 169.354 167.912 1.00 85.67  ? 812 ACD A C6  1 
HETATM 7497 C C7  . ACD BA 6 .   ? 192.653 169.580 168.925 1.00 83.26  ? 812 ACD A C7  1 
HETATM 7498 C C8  . ACD BA 6 .   ? 193.181 169.433 170.323 1.00 80.22  ? 812 ACD A C8  1 
HETATM 7499 C C9  . ACD BA 6 .   ? 192.636 168.747 171.326 1.00 82.41  ? 812 ACD A C9  1 
HETATM 7500 C C10 . ACD BA 6 .   ? 193.165 168.601 172.724 1.00 81.98  ? 812 ACD A C10 1 
HETATM 7501 C C11 . ACD BA 6 .   ? 192.044 168.597 173.723 1.00 82.42  ? 812 ACD A C11 1 
HETATM 7502 C C12 . ACD BA 6 .   ? 192.014 169.207 174.906 1.00 81.55  ? 812 ACD A C12 1 
HETATM 7503 C C13 . ACD BA 6 .   ? 193.099 170.045 175.517 1.00 84.68  ? 812 ACD A C13 1 
HETATM 7504 C C14 . ACD BA 6 .   ? 192.938 170.130 177.009 1.00 81.55  ? 812 ACD A C14 1 
HETATM 7505 C C15 . ACD BA 6 .   ? 191.923 169.700 177.756 1.00 79.41  ? 812 ACD A C15 1 
HETATM 7506 C C16 . ACD BA 6 .   ? 191.769 169.794 179.240 1.00 80.80  ? 812 ACD A C16 1 
HETATM 7507 C C17 . ACD BA 6 .   ? 191.036 168.587 179.827 1.00 82.33  ? 812 ACD A C17 1 
HETATM 7508 C C18 . ACD BA 6 .   ? 190.900 168.660 181.341 1.00 82.18  ? 812 ACD A C18 1 
HETATM 7509 C C19 . ACD BA 6 .   ? 190.305 167.398 181.954 1.00 83.70  ? 812 ACD A C19 1 
HETATM 7510 C C20 . ACD BA 6 .   ? 190.208 167.470 183.471 1.00 79.63  ? 812 ACD A C20 1 
HETATM 7511 O O1  . ACD BA 6 .   ? 196.443 170.344 162.572 1.00 87.05  ? 812 ACD A O1  1 
HETATM 7512 O O2  . ACD BA 6 .   ? 196.532 168.140 162.864 1.00 85.67  ? 812 ACD A O2  1 
HETATM 7513 O O   . HOH CA 7 .   ? 167.591 220.773 202.428 1.00 30.00  ? 901 HOH B O   1 
HETATM 7514 O O   . HOH CA 7 .   ? 174.830 220.856 192.485 1.00 30.00  ? 902 HOH B O   1 
HETATM 7515 O O   . HOH CA 7 .   ? 172.386 222.842 190.249 1.00 30.00  ? 903 HOH B O   1 
HETATM 7516 O O   . HOH CA 7 .   ? 170.739 222.642 203.299 1.00 30.00  ? 904 HOH B O   1 
HETATM 7517 O O   . HOH DA 7 .   ? 210.063 156.890 202.423 1.00 30.00  ? 901 HOH A O   1 
HETATM 7518 O O   . HOH DA 7 .   ? 202.829 156.809 192.485 1.00 30.00  ? 902 HOH A O   1 
HETATM 7519 O O   . HOH DA 7 .   ? 205.274 154.818 190.249 1.00 30.00  ? 903 HOH A O   1 
HETATM 7520 O O   . HOH DA 7 .   ? 206.921 155.018 203.299 1.00 30.00  ? 904 HOH A O   1 
# 
