data_9IML
# 
_entry.id   9IML 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9IML         pdb_00009iml 10.2210/pdb9iml/pdb 
WWPDB D_1300049150 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'Structure model' 1 1 2025-03-26 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9IML 
_pdbx_database_status.recvd_initial_deposition_date   2024-07-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              nxzhang@simm.ac.cn 
_pdbx_contact_author.name_first         Naixia 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4824-5819 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Shi, L.'   1 ? 
'Xu, Z.'    2 ? 
'Chen, X.'  3 ? 
'Xiong, B.' 4 ? 
'Zhang, N.' 5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            68 
_citation.language                  ? 
_citation.page_first                5874 
_citation.page_last                 5890 
_citation.title                     
'Sertraline and Astemizole Enhance the Deubiquitinase Activity of USP7 by Binding to Its Switching Loop Region.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.5c00032 
_citation.pdbx_database_id_PubMed   39999290 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Shi, L.'   1 ? 
primary 'Xu, Z.'    2 ? 
primary 'Chen, X.'  3 ? 
primary 'Meng, Q.'  4 ? 
primary 'Zhou, H.'  5 ? 
primary 'Xiong, B.' 6 ? 
primary 'Zhang, N.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Ubiquitin carboxyl-terminal hydrolase 7'                                                           41004.340 4  
3.4.19.12 ? ? ? 
2 polymer     man Ubiquitin                                                                                           8519.778  4  
?         ? ? ? 
3 non-polymer nat '1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine' 458.570   1  
?         ? ? ? 
4 water       nat water                                                                                               18.015    41 
?         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWET
LDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDY
VAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN
YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEV
LQAVTDHDIPQQLVERLQEEKRIEAQKRKERQE
;
;KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWET
LDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDY
VAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN
YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEV
LQAVTDHDIPQQLVERLQEEKRIEAQKRKERQE
;
A,C,E,G ? 
2 'polypeptide(L)' no no MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG 
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG B,D,F,H ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 '1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine' XB7 
4 water                                                                                               HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   LYS n 
1 2   LYS n 
1 3   HIS n 
1 4   THR n 
1 5   GLY n 
1 6   TYR n 
1 7   VAL n 
1 8   GLY n 
1 9   LEU n 
1 10  LYS n 
1 11  ASN n 
1 12  GLN n 
1 13  GLY n 
1 14  ALA n 
1 15  THR n 
1 16  CYS n 
1 17  TYR n 
1 18  MET n 
1 19  ASN n 
1 20  SER n 
1 21  LEU n 
1 22  LEU n 
1 23  GLN n 
1 24  THR n 
1 25  LEU n 
1 26  PHE n 
1 27  PHE n 
1 28  THR n 
1 29  ASN n 
1 30  GLN n 
1 31  LEU n 
1 32  ARG n 
1 33  LYS n 
1 34  ALA n 
1 35  VAL n 
1 36  TYR n 
1 37  MET n 
1 38  MET n 
1 39  PRO n 
1 40  THR n 
1 41  GLU n 
1 42  GLY n 
1 43  ASP n 
1 44  ASP n 
1 45  SER n 
1 46  SER n 
1 47  LYS n 
1 48  SER n 
1 49  VAL n 
1 50  PRO n 
1 51  LEU n 
1 52  ALA n 
1 53  LEU n 
1 54  GLN n 
1 55  ARG n 
1 56  VAL n 
1 57  PHE n 
1 58  TYR n 
1 59  GLU n 
1 60  LEU n 
1 61  GLN n 
1 62  HIS n 
1 63  SER n 
1 64  ASP n 
1 65  LYS n 
1 66  PRO n 
1 67  VAL n 
1 68  GLY n 
1 69  THR n 
1 70  LYS n 
1 71  LYS n 
1 72  LEU n 
1 73  THR n 
1 74  LYS n 
1 75  SER n 
1 76  PHE n 
1 77  GLY n 
1 78  TRP n 
1 79  GLU n 
1 80  THR n 
1 81  LEU n 
1 82  ASP n 
1 83  SER n 
1 84  PHE n 
1 85  MET n 
1 86  GLN n 
1 87  HIS n 
1 88  ASP n 
1 89  VAL n 
1 90  GLN n 
1 91  GLU n 
1 92  LEU n 
1 93  CYS n 
1 94  ARG n 
1 95  VAL n 
1 96  LEU n 
1 97  LEU n 
1 98  ASP n 
1 99  ASN n 
1 100 VAL n 
1 101 GLU n 
1 102 ASN n 
1 103 LYS n 
1 104 MET n 
1 105 LYS n 
1 106 GLY n 
1 107 THR n 
1 108 CYS n 
1 109 VAL n 
1 110 GLU n 
1 111 GLY n 
1 112 THR n 
1 113 ILE n 
1 114 PRO n 
1 115 LYS n 
1 116 LEU n 
1 117 PHE n 
1 118 ARG n 
1 119 GLY n 
1 120 LYS n 
1 121 MET n 
1 122 VAL n 
1 123 SER n 
1 124 TYR n 
1 125 ILE n 
1 126 GLN n 
1 127 CYS n 
1 128 LYS n 
1 129 GLU n 
1 130 VAL n 
1 131 ASP n 
1 132 TYR n 
1 133 ARG n 
1 134 SER n 
1 135 ASP n 
1 136 ARG n 
1 137 ARG n 
1 138 GLU n 
1 139 ASP n 
1 140 TYR n 
1 141 TYR n 
1 142 ASP n 
1 143 ILE n 
1 144 GLN n 
1 145 LEU n 
1 146 SER n 
1 147 ILE n 
1 148 LYS n 
1 149 GLY n 
1 150 LYS n 
1 151 LYS n 
1 152 ASN n 
1 153 ILE n 
1 154 PHE n 
1 155 GLU n 
1 156 SER n 
1 157 PHE n 
1 158 VAL n 
1 159 ASP n 
1 160 TYR n 
1 161 VAL n 
1 162 ALA n 
1 163 VAL n 
1 164 GLU n 
1 165 GLN n 
1 166 LEU n 
1 167 ASP n 
1 168 GLY n 
1 169 ASP n 
1 170 ASN n 
1 171 LYS n 
1 172 TYR n 
1 173 ASP n 
1 174 ALA n 
1 175 GLY n 
1 176 GLU n 
1 177 HIS n 
1 178 GLY n 
1 179 LEU n 
1 180 GLN n 
1 181 GLU n 
1 182 ALA n 
1 183 GLU n 
1 184 LYS n 
1 185 GLY n 
1 186 VAL n 
1 187 LYS n 
1 188 PHE n 
1 189 LEU n 
1 190 THR n 
1 191 LEU n 
1 192 PRO n 
1 193 PRO n 
1 194 VAL n 
1 195 LEU n 
1 196 HIS n 
1 197 LEU n 
1 198 GLN n 
1 199 LEU n 
1 200 MET n 
1 201 ARG n 
1 202 PHE n 
1 203 MET n 
1 204 TYR n 
1 205 ASP n 
1 206 PRO n 
1 207 GLN n 
1 208 THR n 
1 209 ASP n 
1 210 GLN n 
1 211 ASN n 
1 212 ILE n 
1 213 LYS n 
1 214 ILE n 
1 215 ASN n 
1 216 ASP n 
1 217 ARG n 
1 218 PHE n 
1 219 GLU n 
1 220 PHE n 
1 221 PRO n 
1 222 GLU n 
1 223 GLN n 
1 224 LEU n 
1 225 PRO n 
1 226 LEU n 
1 227 ASP n 
1 228 GLU n 
1 229 PHE n 
1 230 LEU n 
1 231 GLN n 
1 232 LYS n 
1 233 THR n 
1 234 ASP n 
1 235 PRO n 
1 236 LYS n 
1 237 ASP n 
1 238 PRO n 
1 239 ALA n 
1 240 ASN n 
1 241 TYR n 
1 242 ILE n 
1 243 LEU n 
1 244 HIS n 
1 245 ALA n 
1 246 VAL n 
1 247 LEU n 
1 248 VAL n 
1 249 HIS n 
1 250 SER n 
1 251 GLY n 
1 252 ASP n 
1 253 ASN n 
1 254 HIS n 
1 255 GLY n 
1 256 GLY n 
1 257 HIS n 
1 258 TYR n 
1 259 VAL n 
1 260 VAL n 
1 261 TYR n 
1 262 LEU n 
1 263 ASN n 
1 264 PRO n 
1 265 LYS n 
1 266 GLY n 
1 267 ASP n 
1 268 GLY n 
1 269 LYS n 
1 270 TRP n 
1 271 CYS n 
1 272 LYS n 
1 273 PHE n 
1 274 ASP n 
1 275 ASP n 
1 276 ASP n 
1 277 VAL n 
1 278 VAL n 
1 279 SER n 
1 280 ARG n 
1 281 CYS n 
1 282 THR n 
1 283 LYS n 
1 284 GLU n 
1 285 GLU n 
1 286 ALA n 
1 287 ILE n 
1 288 GLU n 
1 289 HIS n 
1 290 ASN n 
1 291 TYR n 
1 292 GLY n 
1 293 GLY n 
1 294 HIS n 
1 295 ASP n 
1 296 ASP n 
1 297 ASP n 
1 298 LEU n 
1 299 SER n 
1 300 VAL n 
1 301 ARG n 
1 302 HIS n 
1 303 CYS n 
1 304 THR n 
1 305 ASN n 
1 306 ALA n 
1 307 TYR n 
1 308 MET n 
1 309 LEU n 
1 310 VAL n 
1 311 TYR n 
1 312 ILE n 
1 313 ARG n 
1 314 GLU n 
1 315 SER n 
1 316 LYS n 
1 317 LEU n 
1 318 SER n 
1 319 GLU n 
1 320 VAL n 
1 321 LEU n 
1 322 GLN n 
1 323 ALA n 
1 324 VAL n 
1 325 THR n 
1 326 ASP n 
1 327 HIS n 
1 328 ASP n 
1 329 ILE n 
1 330 PRO n 
1 331 GLN n 
1 332 GLN n 
1 333 LEU n 
1 334 VAL n 
1 335 GLU n 
1 336 ARG n 
1 337 LEU n 
1 338 GLN n 
1 339 GLU n 
1 340 GLU n 
1 341 LYS n 
1 342 ARG n 
1 343 ILE n 
1 344 GLU n 
1 345 ALA n 
1 346 GLN n 
1 347 LYS n 
1 348 ARG n 
1 349 LYS n 
1 350 GLU n 
1 351 ARG n 
1 352 GLN n 
1 353 GLU n 
2 1   MET n 
2 2   GLN n 
2 3   ILE n 
2 4   PHE n 
2 5   VAL n 
2 6   LYS n 
2 7   THR n 
2 8   LEU n 
2 9   THR n 
2 10  GLY n 
2 11  LYS n 
2 12  THR n 
2 13  ILE n 
2 14  THR n 
2 15  LEU n 
2 16  GLU n 
2 17  VAL n 
2 18  GLU n 
2 19  PRO n 
2 20  SER n 
2 21  ASP n 
2 22  THR n 
2 23  ILE n 
2 24  GLU n 
2 25  ASN n 
2 26  VAL n 
2 27  LYS n 
2 28  ALA n 
2 29  LYS n 
2 30  ILE n 
2 31  GLN n 
2 32  ASP n 
2 33  LYS n 
2 34  GLU n 
2 35  GLY n 
2 36  ILE n 
2 37  PRO n 
2 38  PRO n 
2 39  ASP n 
2 40  GLN n 
2 41  GLN n 
2 42  ARG n 
2 43  LEU n 
2 44  ILE n 
2 45  PHE n 
2 46  ALA n 
2 47  GLY n 
2 48  LYS n 
2 49  GLN n 
2 50  LEU n 
2 51  GLU n 
2 52  ASP n 
2 53  GLY n 
2 54  ARG n 
2 55  THR n 
2 56  LEU n 
2 57  SER n 
2 58  ASP n 
2 59  TYR n 
2 60  ASN n 
2 61  ILE n 
2 62  GLN n 
2 63  LYS n 
2 64  GLU n 
2 65  SER n 
2 66  THR n 
2 67  LEU n 
2 68  HIS n 
2 69  LEU n 
2 70  VAL n 
2 71  LEU n 
2 72  ARG n 
2 73  LEU n 
2 74  ARG n 
2 75  GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 353 human ? 'USP7, HAUSP'           ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 75  human ? 'RPS27A, UBA80, UBCEP1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                                             ? 
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                                                                            ? 
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                                          ? 
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                                     ? 
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                                                                            ? 
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                                           ? 
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                                     ? 
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                                                                             ? 
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                                           ? 
'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                                                                               ? 
'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                                          ? 
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                                                                             ? 
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                                                              ? 
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                                                          ? 
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                                                                       ? 
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                                                                             ? 
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                                                                              ? 
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                                                                           ? 
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                                          ? 
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                                                            ? 
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                                                              ? 
'C5 H11 N O2'    117.146 
XB7 non-polymer         . '1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine' ? 
'C28 H31 F N4 O' 458.570 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   LYS 1   208 ?   ?   ?   A . n 
A 1 2   LYS 2   209 ?   ?   ?   A . n 
A 1 3   HIS 3   210 ?   ?   ?   A . n 
A 1 4   THR 4   211 211 THR THR A . n 
A 1 5   GLY 5   212 212 GLY GLY A . n 
A 1 6   TYR 6   213 213 TYR TYR A . n 
A 1 7   VAL 7   214 214 VAL VAL A . n 
A 1 8   GLY 8   215 215 GLY GLY A . n 
A 1 9   LEU 9   216 216 LEU LEU A . n 
A 1 10  LYS 10  217 217 LYS LYS A . n 
A 1 11  ASN 11  218 218 ASN ASN A . n 
A 1 12  GLN 12  219 219 GLN GLN A . n 
A 1 13  GLY 13  220 220 GLY GLY A . n 
A 1 14  ALA 14  221 221 ALA ALA A . n 
A 1 15  THR 15  222 222 THR THR A . n 
A 1 16  CYS 16  223 223 CYS CYS A . n 
A 1 17  TYR 17  224 224 TYR TYR A . n 
A 1 18  MET 18  225 225 MET MET A . n 
A 1 19  ASN 19  226 226 ASN ASN A . n 
A 1 20  SER 20  227 227 SER SER A . n 
A 1 21  LEU 21  228 228 LEU LEU A . n 
A 1 22  LEU 22  229 229 LEU LEU A . n 
A 1 23  GLN 23  230 230 GLN GLN A . n 
A 1 24  THR 24  231 231 THR THR A . n 
A 1 25  LEU 25  232 232 LEU LEU A . n 
A 1 26  PHE 26  233 233 PHE PHE A . n 
A 1 27  PHE 27  234 234 PHE PHE A . n 
A 1 28  THR 28  235 235 THR THR A . n 
A 1 29  ASN 29  236 236 ASN ASN A . n 
A 1 30  GLN 30  237 237 GLN GLN A . n 
A 1 31  LEU 31  238 238 LEU LEU A . n 
A 1 32  ARG 32  239 239 ARG ARG A . n 
A 1 33  LYS 33  240 240 LYS LYS A . n 
A 1 34  ALA 34  241 241 ALA ALA A . n 
A 1 35  VAL 35  242 242 VAL VAL A . n 
A 1 36  TYR 36  243 243 TYR TYR A . n 
A 1 37  MET 37  244 244 MET MET A . n 
A 1 38  MET 38  245 245 MET MET A . n 
A 1 39  PRO 39  246 246 PRO PRO A . n 
A 1 40  THR 40  247 247 THR THR A . n 
A 1 41  GLU 41  248 248 GLU GLU A . n 
A 1 42  GLY 42  249 249 GLY GLY A . n 
A 1 43  ASP 43  250 250 ASP ASP A . n 
A 1 44  ASP 44  251 251 ASP ASP A . n 
A 1 45  SER 45  252 252 SER SER A . n 
A 1 46  SER 46  253 253 SER SER A . n 
A 1 47  LYS 47  254 254 LYS LYS A . n 
A 1 48  SER 48  255 255 SER SER A . n 
A 1 49  VAL 49  256 256 VAL VAL A . n 
A 1 50  PRO 50  257 257 PRO PRO A . n 
A 1 51  LEU 51  258 258 LEU LEU A . n 
A 1 52  ALA 52  259 259 ALA ALA A . n 
A 1 53  LEU 53  260 260 LEU LEU A . n 
A 1 54  GLN 54  261 261 GLN GLN A . n 
A 1 55  ARG 55  262 262 ARG ARG A . n 
A 1 56  VAL 56  263 263 VAL VAL A . n 
A 1 57  PHE 57  264 264 PHE PHE A . n 
A 1 58  TYR 58  265 265 TYR TYR A . n 
A 1 59  GLU 59  266 266 GLU GLU A . n 
A 1 60  LEU 60  267 267 LEU LEU A . n 
A 1 61  GLN 61  268 268 GLN GLN A . n 
A 1 62  HIS 62  269 269 HIS HIS A . n 
A 1 63  SER 63  270 270 SER SER A . n 
A 1 64  ASP 64  271 271 ASP ASP A . n 
A 1 65  LYS 65  272 272 LYS LYS A . n 
A 1 66  PRO 66  273 273 PRO PRO A . n 
A 1 67  VAL 67  274 274 VAL VAL A . n 
A 1 68  GLY 68  275 275 GLY GLY A . n 
A 1 69  THR 69  276 276 THR THR A . n 
A 1 70  LYS 70  277 277 LYS LYS A . n 
A 1 71  LYS 71  278 278 LYS LYS A . n 
A 1 72  LEU 72  279 279 LEU LEU A . n 
A 1 73  THR 73  280 280 THR THR A . n 
A 1 74  LYS 74  281 281 LYS LYS A . n 
A 1 75  SER 75  282 282 SER SER A . n 
A 1 76  PHE 76  283 283 PHE PHE A . n 
A 1 77  GLY 77  284 284 GLY GLY A . n 
A 1 78  TRP 78  285 285 TRP TRP A . n 
A 1 79  GLU 79  286 286 GLU GLU A . n 
A 1 80  THR 80  287 287 THR THR A . n 
A 1 81  LEU 81  288 288 LEU LEU A . n 
A 1 82  ASP 82  289 289 ASP ASP A . n 
A 1 83  SER 83  290 290 SER SER A . n 
A 1 84  PHE 84  291 291 PHE PHE A . n 
A 1 85  MET 85  292 292 MET MET A . n 
A 1 86  GLN 86  293 293 GLN GLN A . n 
A 1 87  HIS 87  294 294 HIS HIS A . n 
A 1 88  ASP 88  295 295 ASP ASP A . n 
A 1 89  VAL 89  296 296 VAL VAL A . n 
A 1 90  GLN 90  297 297 GLN GLN A . n 
A 1 91  GLU 91  298 298 GLU GLU A . n 
A 1 92  LEU 92  299 299 LEU LEU A . n 
A 1 93  CYS 93  300 300 CYS CYS A . n 
A 1 94  ARG 94  301 301 ARG ARG A . n 
A 1 95  VAL 95  302 302 VAL VAL A . n 
A 1 96  LEU 96  303 303 LEU LEU A . n 
A 1 97  LEU 97  304 304 LEU LEU A . n 
A 1 98  ASP 98  305 305 ASP ASP A . n 
A 1 99  ASN 99  306 306 ASN ASN A . n 
A 1 100 VAL 100 307 307 VAL VAL A . n 
A 1 101 GLU 101 308 308 GLU GLU A . n 
A 1 102 ASN 102 309 309 ASN ASN A . n 
A 1 103 LYS 103 310 310 LYS LYS A . n 
A 1 104 MET 104 311 311 MET MET A . n 
A 1 105 LYS 105 312 312 LYS LYS A . n 
A 1 106 GLY 106 313 313 GLY GLY A . n 
A 1 107 THR 107 314 314 THR THR A . n 
A 1 108 CYS 108 315 315 CYS CYS A . n 
A 1 109 VAL 109 316 316 VAL VAL A . n 
A 1 110 GLU 110 317 317 GLU GLU A . n 
A 1 111 GLY 111 318 318 GLY GLY A . n 
A 1 112 THR 112 319 319 THR THR A . n 
A 1 113 ILE 113 320 320 ILE ILE A . n 
A 1 114 PRO 114 321 321 PRO PRO A . n 
A 1 115 LYS 115 322 322 LYS LYS A . n 
A 1 116 LEU 116 323 323 LEU LEU A . n 
A 1 117 PHE 117 324 324 PHE PHE A . n 
A 1 118 ARG 118 325 325 ARG ARG A . n 
A 1 119 GLY 119 326 326 GLY GLY A . n 
A 1 120 LYS 120 327 327 LYS LYS A . n 
A 1 121 MET 121 328 328 MET MET A . n 
A 1 122 VAL 122 329 329 VAL VAL A . n 
A 1 123 SER 123 330 330 SER SER A . n 
A 1 124 TYR 124 331 331 TYR TYR A . n 
A 1 125 ILE 125 332 332 ILE ILE A . n 
A 1 126 GLN 126 333 333 GLN GLN A . n 
A 1 127 CYS 127 334 334 CYS CYS A . n 
A 1 128 LYS 128 335 335 LYS LYS A . n 
A 1 129 GLU 129 336 336 GLU GLU A . n 
A 1 130 VAL 130 337 337 VAL VAL A . n 
A 1 131 ASP 131 338 338 ASP ASP A . n 
A 1 132 TYR 132 339 339 TYR TYR A . n 
A 1 133 ARG 133 340 340 ARG ARG A . n 
A 1 134 SER 134 341 341 SER SER A . n 
A 1 135 ASP 135 342 342 ASP ASP A . n 
A 1 136 ARG 136 343 343 ARG ARG A . n 
A 1 137 ARG 137 344 344 ARG ARG A . n 
A 1 138 GLU 138 345 345 GLU GLU A . n 
A 1 139 ASP 139 346 346 ASP ASP A . n 
A 1 140 TYR 140 347 347 TYR TYR A . n 
A 1 141 TYR 141 348 348 TYR TYR A . n 
A 1 142 ASP 142 349 349 ASP ASP A . n 
A 1 143 ILE 143 350 350 ILE ILE A . n 
A 1 144 GLN 144 351 351 GLN GLN A . n 
A 1 145 LEU 145 352 352 LEU LEU A . n 
A 1 146 SER 146 353 353 SER SER A . n 
A 1 147 ILE 147 354 354 ILE ILE A . n 
A 1 148 LYS 148 355 355 LYS LYS A . n 
A 1 149 GLY 149 356 356 GLY GLY A . n 
A 1 150 LYS 150 357 357 LYS LYS A . n 
A 1 151 LYS 151 358 358 LYS LYS A . n 
A 1 152 ASN 152 359 359 ASN ASN A . n 
A 1 153 ILE 153 360 360 ILE ILE A . n 
A 1 154 PHE 154 361 361 PHE PHE A . n 
A 1 155 GLU 155 362 362 GLU GLU A . n 
A 1 156 SER 156 363 363 SER SER A . n 
A 1 157 PHE 157 364 364 PHE PHE A . n 
A 1 158 VAL 158 365 365 VAL VAL A . n 
A 1 159 ASP 159 366 366 ASP ASP A . n 
A 1 160 TYR 160 367 367 TYR TYR A . n 
A 1 161 VAL 161 368 368 VAL VAL A . n 
A 1 162 ALA 162 369 369 ALA ALA A . n 
A 1 163 VAL 163 370 370 VAL VAL A . n 
A 1 164 GLU 164 371 371 GLU GLU A . n 
A 1 165 GLN 165 372 372 GLN GLN A . n 
A 1 166 LEU 166 373 373 LEU LEU A . n 
A 1 167 ASP 167 374 374 ASP ASP A . n 
A 1 168 GLY 168 375 375 GLY GLY A . n 
A 1 169 ASP 169 376 376 ASP ASP A . n 
A 1 170 ASN 170 377 377 ASN ASN A . n 
A 1 171 LYS 171 378 378 LYS LYS A . n 
A 1 172 TYR 172 379 379 TYR TYR A . n 
A 1 173 ASP 173 380 380 ASP ASP A . n 
A 1 174 ALA 174 381 381 ALA ALA A . n 
A 1 175 GLY 175 382 382 GLY GLY A . n 
A 1 176 GLU 176 383 383 GLU GLU A . n 
A 1 177 HIS 177 384 384 HIS HIS A . n 
A 1 178 GLY 178 385 385 GLY GLY A . n 
A 1 179 LEU 179 386 386 LEU LEU A . n 
A 1 180 GLN 180 387 387 GLN GLN A . n 
A 1 181 GLU 181 388 388 GLU GLU A . n 
A 1 182 ALA 182 389 389 ALA ALA A . n 
A 1 183 GLU 183 390 390 GLU GLU A . n 
A 1 184 LYS 184 391 391 LYS LYS A . n 
A 1 185 GLY 185 392 392 GLY GLY A . n 
A 1 186 VAL 186 393 393 VAL VAL A . n 
A 1 187 LYS 187 394 394 LYS LYS A . n 
A 1 188 PHE 188 395 395 PHE PHE A . n 
A 1 189 LEU 189 396 396 LEU LEU A . n 
A 1 190 THR 190 397 397 THR THR A . n 
A 1 191 LEU 191 398 398 LEU LEU A . n 
A 1 192 PRO 192 399 399 PRO PRO A . n 
A 1 193 PRO 193 400 400 PRO PRO A . n 
A 1 194 VAL 194 401 401 VAL VAL A . n 
A 1 195 LEU 195 402 402 LEU LEU A . n 
A 1 196 HIS 196 403 403 HIS HIS A . n 
A 1 197 LEU 197 404 404 LEU LEU A . n 
A 1 198 GLN 198 405 405 GLN GLN A . n 
A 1 199 LEU 199 406 406 LEU LEU A . n 
A 1 200 MET 200 407 407 MET MET A . n 
A 1 201 ARG 201 408 408 ARG ARG A . n 
A 1 202 PHE 202 409 409 PHE PHE A . n 
A 1 203 MET 203 410 410 MET MET A . n 
A 1 204 TYR 204 411 411 TYR TYR A . n 
A 1 205 ASP 205 412 ?   ?   ?   A . n 
A 1 206 PRO 206 413 ?   ?   ?   A . n 
A 1 207 GLN 207 414 ?   ?   ?   A . n 
A 1 208 THR 208 415 ?   ?   ?   A . n 
A 1 209 ASP 209 416 ?   ?   ?   A . n 
A 1 210 GLN 210 417 ?   ?   ?   A . n 
A 1 211 ASN 211 418 418 ASN ASN A . n 
A 1 212 ILE 212 419 419 ILE ILE A . n 
A 1 213 LYS 213 420 420 LYS LYS A . n 
A 1 214 ILE 214 421 421 ILE ILE A . n 
A 1 215 ASN 215 422 422 ASN ASN A . n 
A 1 216 ASP 216 423 423 ASP ASP A . n 
A 1 217 ARG 217 424 424 ARG ARG A . n 
A 1 218 PHE 218 425 425 PHE PHE A . n 
A 1 219 GLU 219 426 426 GLU GLU A . n 
A 1 220 PHE 220 427 427 PHE PHE A . n 
A 1 221 PRO 221 428 428 PRO PRO A . n 
A 1 222 GLU 222 429 429 GLU GLU A . n 
A 1 223 GLN 223 430 430 GLN GLN A . n 
A 1 224 LEU 224 431 431 LEU LEU A . n 
A 1 225 PRO 225 432 432 PRO PRO A . n 
A 1 226 LEU 226 433 433 LEU LEU A . n 
A 1 227 ASP 227 434 434 ASP ASP A . n 
A 1 228 GLU 228 435 435 GLU GLU A . n 
A 1 229 PHE 229 436 436 PHE PHE A . n 
A 1 230 LEU 230 437 437 LEU LEU A . n 
A 1 231 GLN 231 438 438 GLN GLN A . n 
A 1 232 LYS 232 439 439 LYS LYS A . n 
A 1 233 THR 233 440 440 THR THR A . n 
A 1 234 ASP 234 441 441 ASP ASP A . n 
A 1 235 PRO 235 442 442 PRO PRO A . n 
A 1 236 LYS 236 443 443 LYS LYS A . n 
A 1 237 ASP 237 444 444 ASP ASP A . n 
A 1 238 PRO 238 445 445 PRO PRO A . n 
A 1 239 ALA 239 446 446 ALA ALA A . n 
A 1 240 ASN 240 447 447 ASN ASN A . n 
A 1 241 TYR 241 448 448 TYR TYR A . n 
A 1 242 ILE 242 449 449 ILE ILE A . n 
A 1 243 LEU 243 450 450 LEU LEU A . n 
A 1 244 HIS 244 451 451 HIS HIS A . n 
A 1 245 ALA 245 452 452 ALA ALA A . n 
A 1 246 VAL 246 453 453 VAL VAL A . n 
A 1 247 LEU 247 454 454 LEU LEU A . n 
A 1 248 VAL 248 455 455 VAL VAL A . n 
A 1 249 HIS 249 456 456 HIS HIS A . n 
A 1 250 SER 250 457 457 SER SER A . n 
A 1 251 GLY 251 458 458 GLY GLY A . n 
A 1 252 ASP 252 459 459 ASP ASP A . n 
A 1 253 ASN 253 460 ?   ?   ?   A . n 
A 1 254 HIS 254 461 ?   ?   ?   A . n 
A 1 255 GLY 255 462 462 GLY GLY A . n 
A 1 256 GLY 256 463 463 GLY GLY A . n 
A 1 257 HIS 257 464 464 HIS HIS A . n 
A 1 258 TYR 258 465 465 TYR TYR A . n 
A 1 259 VAL 259 466 466 VAL VAL A . n 
A 1 260 VAL 260 467 467 VAL VAL A . n 
A 1 261 TYR 261 468 468 TYR TYR A . n 
A 1 262 LEU 262 469 469 LEU LEU A . n 
A 1 263 ASN 263 470 470 ASN ASN A . n 
A 1 264 PRO 264 471 471 PRO PRO A . n 
A 1 265 LYS 265 472 472 LYS LYS A . n 
A 1 266 GLY 266 473 473 GLY GLY A . n 
A 1 267 ASP 267 474 474 ASP ASP A . n 
A 1 268 GLY 268 475 475 GLY GLY A . n 
A 1 269 LYS 269 476 476 LYS LYS A . n 
A 1 270 TRP 270 477 477 TRP TRP A . n 
A 1 271 CYS 271 478 478 CYS CYS A . n 
A 1 272 LYS 272 479 479 LYS LYS A . n 
A 1 273 PHE 273 480 480 PHE PHE A . n 
A 1 274 ASP 274 481 481 ASP ASP A . n 
A 1 275 ASP 275 482 482 ASP ASP A . n 
A 1 276 ASP 276 483 483 ASP ASP A . n 
A 1 277 VAL 277 484 484 VAL VAL A . n 
A 1 278 VAL 278 485 485 VAL VAL A . n 
A 1 279 SER 279 486 486 SER SER A . n 
A 1 280 ARG 280 487 487 ARG ARG A . n 
A 1 281 CYS 281 488 488 CYS CYS A . n 
A 1 282 THR 282 489 489 THR THR A . n 
A 1 283 LYS 283 490 490 LYS LYS A . n 
A 1 284 GLU 284 491 491 GLU GLU A . n 
A 1 285 GLU 285 492 492 GLU GLU A . n 
A 1 286 ALA 286 493 493 ALA ALA A . n 
A 1 287 ILE 287 494 494 ILE ILE A . n 
A 1 288 GLU 288 495 495 GLU GLU A . n 
A 1 289 HIS 289 496 496 HIS HIS A . n 
A 1 290 ASN 290 497 497 ASN ASN A . n 
A 1 291 TYR 291 498 498 TYR TYR A . n 
A 1 292 GLY 292 499 499 GLY GLY A . n 
A 1 293 GLY 293 500 500 GLY GLY A . n 
A 1 294 HIS 294 501 ?   ?   ?   A . n 
A 1 295 ASP 295 502 ?   ?   ?   A . n 
A 1 296 ASP 296 503 ?   ?   ?   A . n 
A 1 297 ASP 297 504 ?   ?   ?   A . n 
A 1 298 LEU 298 505 ?   ?   ?   A . n 
A 1 299 SER 299 506 ?   ?   ?   A . n 
A 1 300 VAL 300 507 ?   ?   ?   A . n 
A 1 301 ARG 301 508 ?   ?   ?   A . n 
A 1 302 HIS 302 509 ?   ?   ?   A . n 
A 1 303 CYS 303 510 510 CYS CYS A . n 
A 1 304 THR 304 511 511 THR THR A . n 
A 1 305 ASN 305 512 512 ASN ASN A . n 
A 1 306 ALA 306 513 513 ALA ALA A . n 
A 1 307 TYR 307 514 514 TYR TYR A . n 
A 1 308 MET 308 515 515 MET MET A . n 
A 1 309 LEU 309 516 516 LEU LEU A . n 
A 1 310 VAL 310 517 517 VAL VAL A . n 
A 1 311 TYR 311 518 518 TYR TYR A . n 
A 1 312 ILE 312 519 519 ILE ILE A . n 
A 1 313 ARG 313 520 520 ARG ARG A . n 
A 1 314 GLU 314 521 521 GLU GLU A . n 
A 1 315 SER 315 522 522 SER SER A . n 
A 1 316 LYS 316 523 523 LYS LYS A . n 
A 1 317 LEU 317 524 524 LEU LEU A . n 
A 1 318 SER 318 525 525 SER SER A . n 
A 1 319 GLU 319 526 526 GLU GLU A . n 
A 1 320 VAL 320 527 527 VAL VAL A . n 
A 1 321 LEU 321 528 528 LEU LEU A . n 
A 1 322 GLN 322 529 529 GLN GLN A . n 
A 1 323 ALA 323 530 530 ALA ALA A . n 
A 1 324 VAL 324 531 531 VAL VAL A . n 
A 1 325 THR 325 532 532 THR THR A . n 
A 1 326 ASP 326 533 533 ASP ASP A . n 
A 1 327 HIS 327 534 534 HIS HIS A . n 
A 1 328 ASP 328 535 535 ASP ASP A . n 
A 1 329 ILE 329 536 536 ILE ILE A . n 
A 1 330 PRO 330 537 537 PRO PRO A . n 
A 1 331 GLN 331 538 538 GLN GLN A . n 
A 1 332 GLN 332 539 539 GLN GLN A . n 
A 1 333 LEU 333 540 540 LEU LEU A . n 
A 1 334 VAL 334 541 541 VAL VAL A . n 
A 1 335 GLU 335 542 542 GLU GLU A . n 
A 1 336 ARG 336 543 543 ARG ARG A . n 
A 1 337 LEU 337 544 544 LEU LEU A . n 
A 1 338 GLN 338 545 545 GLN GLN A . n 
A 1 339 GLU 339 546 546 GLU GLU A . n 
A 1 340 GLU 340 547 547 GLU GLU A . n 
A 1 341 LYS 341 548 ?   ?   ?   A . n 
A 1 342 ARG 342 549 ?   ?   ?   A . n 
A 1 343 ILE 343 550 ?   ?   ?   A . n 
A 1 344 GLU 344 551 ?   ?   ?   A . n 
A 1 345 ALA 345 552 ?   ?   ?   A . n 
A 1 346 GLN 346 553 ?   ?   ?   A . n 
A 1 347 LYS 347 554 ?   ?   ?   A . n 
A 1 348 ARG 348 555 ?   ?   ?   A . n 
A 1 349 LYS 349 556 ?   ?   ?   A . n 
A 1 350 GLU 350 557 ?   ?   ?   A . n 
A 1 351 ARG 351 558 ?   ?   ?   A . n 
A 1 352 GLN 352 559 ?   ?   ?   A . n 
A 1 353 GLU 353 560 ?   ?   ?   A . n 
B 2 1   MET 1   1   1   MET MET B . n 
B 2 2   GLN 2   2   2   GLN GLN B . n 
B 2 3   ILE 3   3   3   ILE ILE B . n 
B 2 4   PHE 4   4   4   PHE PHE B . n 
B 2 5   VAL 5   5   5   VAL VAL B . n 
B 2 6   LYS 6   6   6   LYS LYS B . n 
B 2 7   THR 7   7   7   THR THR B . n 
B 2 8   LEU 8   8   8   LEU LEU B . n 
B 2 9   THR 9   9   9   THR THR B . n 
B 2 10  GLY 10  10  10  GLY GLY B . n 
B 2 11  LYS 11  11  11  LYS LYS B . n 
B 2 12  THR 12  12  12  THR THR B . n 
B 2 13  ILE 13  13  13  ILE ILE B . n 
B 2 14  THR 14  14  14  THR THR B . n 
B 2 15  LEU 15  15  15  LEU LEU B . n 
B 2 16  GLU 16  16  16  GLU GLU B . n 
B 2 17  VAL 17  17  17  VAL VAL B . n 
B 2 18  GLU 18  18  18  GLU GLU B . n 
B 2 19  PRO 19  19  19  PRO PRO B . n 
B 2 20  SER 20  20  20  SER SER B . n 
B 2 21  ASP 21  21  21  ASP ASP B . n 
B 2 22  THR 22  22  22  THR THR B . n 
B 2 23  ILE 23  23  23  ILE ILE B . n 
B 2 24  GLU 24  24  24  GLU GLU B . n 
B 2 25  ASN 25  25  25  ASN ASN B . n 
B 2 26  VAL 26  26  26  VAL VAL B . n 
B 2 27  LYS 27  27  27  LYS LYS B . n 
B 2 28  ALA 28  28  28  ALA ALA B . n 
B 2 29  LYS 29  29  29  LYS LYS B . n 
B 2 30  ILE 30  30  30  ILE ILE B . n 
B 2 31  GLN 31  31  31  GLN GLN B . n 
B 2 32  ASP 32  32  32  ASP ASP B . n 
B 2 33  LYS 33  33  33  LYS LYS B . n 
B 2 34  GLU 34  34  34  GLU GLU B . n 
B 2 35  GLY 35  35  35  GLY GLY B . n 
B 2 36  ILE 36  36  36  ILE ILE B . n 
B 2 37  PRO 37  37  37  PRO PRO B . n 
B 2 38  PRO 38  38  38  PRO PRO B . n 
B 2 39  ASP 39  39  39  ASP ASP B . n 
B 2 40  GLN 40  40  40  GLN GLN B . n 
B 2 41  GLN 41  41  41  GLN GLN B . n 
B 2 42  ARG 42  42  42  ARG ARG B . n 
B 2 43  LEU 43  43  43  LEU LEU B . n 
B 2 44  ILE 44  44  44  ILE ILE B . n 
B 2 45  PHE 45  45  45  PHE PHE B . n 
B 2 46  ALA 46  46  46  ALA ALA B . n 
B 2 47  GLY 47  47  47  GLY GLY B . n 
B 2 48  LYS 48  48  48  LYS LYS B . n 
B 2 49  GLN 49  49  49  GLN GLN B . n 
B 2 50  LEU 50  50  50  LEU LEU B . n 
B 2 51  GLU 51  51  51  GLU GLU B . n 
B 2 52  ASP 52  52  52  ASP ASP B . n 
B 2 53  GLY 53  53  53  GLY GLY B . n 
B 2 54  ARG 54  54  54  ARG ARG B . n 
B 2 55  THR 55  55  55  THR THR B . n 
B 2 56  LEU 56  56  56  LEU LEU B . n 
B 2 57  SER 57  57  57  SER SER B . n 
B 2 58  ASP 58  58  58  ASP ASP B . n 
B 2 59  TYR 59  59  59  TYR TYR B . n 
B 2 60  ASN 60  60  60  ASN ASN B . n 
B 2 61  ILE 61  61  61  ILE ILE B . n 
B 2 62  GLN 62  62  62  GLN GLN B . n 
B 2 63  LYS 63  63  63  LYS LYS B . n 
B 2 64  GLU 64  64  64  GLU GLU B . n 
B 2 65  SER 65  65  65  SER SER B . n 
B 2 66  THR 66  66  66  THR THR B . n 
B 2 67  LEU 67  67  67  LEU LEU B . n 
B 2 68  HIS 68  68  68  HIS HIS B . n 
B 2 69  LEU 69  69  69  LEU LEU B . n 
B 2 70  VAL 70  70  70  VAL VAL B . n 
B 2 71  LEU 71  71  71  LEU LEU B . n 
B 2 72  ARG 72  72  72  ARG ARG B . n 
B 2 73  LEU 73  73  73  LEU LEU B . n 
B 2 74  ARG 74  74  74  ARG ARG B . n 
B 2 75  GLY 75  75  75  GLY GLY B . n 
C 1 1   LYS 1   208 ?   ?   ?   C . n 
C 1 2   LYS 2   209 ?   ?   ?   C . n 
C 1 3   HIS 3   210 ?   ?   ?   C . n 
C 1 4   THR 4   211 211 THR THR C . n 
C 1 5   GLY 5   212 212 GLY GLY C . n 
C 1 6   TYR 6   213 213 TYR TYR C . n 
C 1 7   VAL 7   214 214 VAL VAL C . n 
C 1 8   GLY 8   215 215 GLY GLY C . n 
C 1 9   LEU 9   216 216 LEU LEU C . n 
C 1 10  LYS 10  217 217 LYS LYS C . n 
C 1 11  ASN 11  218 218 ASN ASN C . n 
C 1 12  GLN 12  219 219 GLN GLN C . n 
C 1 13  GLY 13  220 220 GLY GLY C . n 
C 1 14  ALA 14  221 221 ALA ALA C . n 
C 1 15  THR 15  222 222 THR THR C . n 
C 1 16  CYS 16  223 223 CYS CYS C . n 
C 1 17  TYR 17  224 224 TYR TYR C . n 
C 1 18  MET 18  225 225 MET MET C . n 
C 1 19  ASN 19  226 226 ASN ASN C . n 
C 1 20  SER 20  227 227 SER SER C . n 
C 1 21  LEU 21  228 228 LEU LEU C . n 
C 1 22  LEU 22  229 229 LEU LEU C . n 
C 1 23  GLN 23  230 230 GLN GLN C . n 
C 1 24  THR 24  231 231 THR THR C . n 
C 1 25  LEU 25  232 232 LEU LEU C . n 
C 1 26  PHE 26  233 233 PHE PHE C . n 
C 1 27  PHE 27  234 234 PHE PHE C . n 
C 1 28  THR 28  235 235 THR THR C . n 
C 1 29  ASN 29  236 236 ASN ASN C . n 
C 1 30  GLN 30  237 237 GLN GLN C . n 
C 1 31  LEU 31  238 238 LEU LEU C . n 
C 1 32  ARG 32  239 239 ARG ARG C . n 
C 1 33  LYS 33  240 240 LYS LYS C . n 
C 1 34  ALA 34  241 241 ALA ALA C . n 
C 1 35  VAL 35  242 242 VAL VAL C . n 
C 1 36  TYR 36  243 243 TYR TYR C . n 
C 1 37  MET 37  244 244 MET MET C . n 
C 1 38  MET 38  245 245 MET MET C . n 
C 1 39  PRO 39  246 246 PRO PRO C . n 
C 1 40  THR 40  247 247 THR THR C . n 
C 1 41  GLU 41  248 248 GLU GLU C . n 
C 1 42  GLY 42  249 ?   ?   ?   C . n 
C 1 43  ASP 43  250 ?   ?   ?   C . n 
C 1 44  ASP 44  251 ?   ?   ?   C . n 
C 1 45  SER 45  252 ?   ?   ?   C . n 
C 1 46  SER 46  253 253 SER SER C . n 
C 1 47  LYS 47  254 254 LYS LYS C . n 
C 1 48  SER 48  255 255 SER SER C . n 
C 1 49  VAL 49  256 256 VAL VAL C . n 
C 1 50  PRO 50  257 257 PRO PRO C . n 
C 1 51  LEU 51  258 258 LEU LEU C . n 
C 1 52  ALA 52  259 259 ALA ALA C . n 
C 1 53  LEU 53  260 260 LEU LEU C . n 
C 1 54  GLN 54  261 261 GLN GLN C . n 
C 1 55  ARG 55  262 262 ARG ARG C . n 
C 1 56  VAL 56  263 263 VAL VAL C . n 
C 1 57  PHE 57  264 264 PHE PHE C . n 
C 1 58  TYR 58  265 265 TYR TYR C . n 
C 1 59  GLU 59  266 266 GLU GLU C . n 
C 1 60  LEU 60  267 267 LEU LEU C . n 
C 1 61  GLN 61  268 268 GLN GLN C . n 
C 1 62  HIS 62  269 269 HIS HIS C . n 
C 1 63  SER 63  270 270 SER SER C . n 
C 1 64  ASP 64  271 271 ASP ASP C . n 
C 1 65  LYS 65  272 272 LYS LYS C . n 
C 1 66  PRO 66  273 273 PRO PRO C . n 
C 1 67  VAL 67  274 274 VAL VAL C . n 
C 1 68  GLY 68  275 275 GLY GLY C . n 
C 1 69  THR 69  276 276 THR THR C . n 
C 1 70  LYS 70  277 277 LYS LYS C . n 
C 1 71  LYS 71  278 278 LYS LYS C . n 
C 1 72  LEU 72  279 279 LEU LEU C . n 
C 1 73  THR 73  280 280 THR THR C . n 
C 1 74  LYS 74  281 281 LYS LYS C . n 
C 1 75  SER 75  282 282 SER SER C . n 
C 1 76  PHE 76  283 283 PHE PHE C . n 
C 1 77  GLY 77  284 284 GLY GLY C . n 
C 1 78  TRP 78  285 285 TRP TRP C . n 
C 1 79  GLU 79  286 286 GLU GLU C . n 
C 1 80  THR 80  287 287 THR THR C . n 
C 1 81  LEU 81  288 288 LEU LEU C . n 
C 1 82  ASP 82  289 289 ASP ASP C . n 
C 1 83  SER 83  290 290 SER SER C . n 
C 1 84  PHE 84  291 291 PHE PHE C . n 
C 1 85  MET 85  292 292 MET MET C . n 
C 1 86  GLN 86  293 293 GLN GLN C . n 
C 1 87  HIS 87  294 294 HIS HIS C . n 
C 1 88  ASP 88  295 295 ASP ASP C . n 
C 1 89  VAL 89  296 296 VAL VAL C . n 
C 1 90  GLN 90  297 297 GLN GLN C . n 
C 1 91  GLU 91  298 298 GLU GLU C . n 
C 1 92  LEU 92  299 299 LEU LEU C . n 
C 1 93  CYS 93  300 300 CYS CYS C . n 
C 1 94  ARG 94  301 301 ARG ARG C . n 
C 1 95  VAL 95  302 302 VAL VAL C . n 
C 1 96  LEU 96  303 303 LEU LEU C . n 
C 1 97  LEU 97  304 304 LEU LEU C . n 
C 1 98  ASP 98  305 305 ASP ASP C . n 
C 1 99  ASN 99  306 306 ASN ASN C . n 
C 1 100 VAL 100 307 307 VAL VAL C . n 
C 1 101 GLU 101 308 308 GLU GLU C . n 
C 1 102 ASN 102 309 309 ASN ASN C . n 
C 1 103 LYS 103 310 310 LYS LYS C . n 
C 1 104 MET 104 311 311 MET MET C . n 
C 1 105 LYS 105 312 312 LYS LYS C . n 
C 1 106 GLY 106 313 313 GLY GLY C . n 
C 1 107 THR 107 314 314 THR THR C . n 
C 1 108 CYS 108 315 315 CYS CYS C . n 
C 1 109 VAL 109 316 316 VAL VAL C . n 
C 1 110 GLU 110 317 317 GLU GLU C . n 
C 1 111 GLY 111 318 318 GLY GLY C . n 
C 1 112 THR 112 319 319 THR THR C . n 
C 1 113 ILE 113 320 320 ILE ILE C . n 
C 1 114 PRO 114 321 321 PRO PRO C . n 
C 1 115 LYS 115 322 322 LYS LYS C . n 
C 1 116 LEU 116 323 323 LEU LEU C . n 
C 1 117 PHE 117 324 324 PHE PHE C . n 
C 1 118 ARG 118 325 325 ARG ARG C . n 
C 1 119 GLY 119 326 326 GLY GLY C . n 
C 1 120 LYS 120 327 327 LYS LYS C . n 
C 1 121 MET 121 328 328 MET MET C . n 
C 1 122 VAL 122 329 329 VAL VAL C . n 
C 1 123 SER 123 330 330 SER SER C . n 
C 1 124 TYR 124 331 331 TYR TYR C . n 
C 1 125 ILE 125 332 332 ILE ILE C . n 
C 1 126 GLN 126 333 333 GLN GLN C . n 
C 1 127 CYS 127 334 334 CYS CYS C . n 
C 1 128 LYS 128 335 335 LYS LYS C . n 
C 1 129 GLU 129 336 336 GLU GLU C . n 
C 1 130 VAL 130 337 337 VAL VAL C . n 
C 1 131 ASP 131 338 338 ASP ASP C . n 
C 1 132 TYR 132 339 339 TYR TYR C . n 
C 1 133 ARG 133 340 340 ARG ARG C . n 
C 1 134 SER 134 341 341 SER SER C . n 
C 1 135 ASP 135 342 342 ASP ASP C . n 
C 1 136 ARG 136 343 343 ARG ARG C . n 
C 1 137 ARG 137 344 344 ARG ARG C . n 
C 1 138 GLU 138 345 345 GLU GLU C . n 
C 1 139 ASP 139 346 346 ASP ASP C . n 
C 1 140 TYR 140 347 347 TYR TYR C . n 
C 1 141 TYR 141 348 348 TYR TYR C . n 
C 1 142 ASP 142 349 349 ASP ASP C . n 
C 1 143 ILE 143 350 350 ILE ILE C . n 
C 1 144 GLN 144 351 351 GLN GLN C . n 
C 1 145 LEU 145 352 352 LEU LEU C . n 
C 1 146 SER 146 353 353 SER SER C . n 
C 1 147 ILE 147 354 354 ILE ILE C . n 
C 1 148 LYS 148 355 355 LYS LYS C . n 
C 1 149 GLY 149 356 356 GLY GLY C . n 
C 1 150 LYS 150 357 357 LYS LYS C . n 
C 1 151 LYS 151 358 358 LYS LYS C . n 
C 1 152 ASN 152 359 359 ASN ASN C . n 
C 1 153 ILE 153 360 360 ILE ILE C . n 
C 1 154 PHE 154 361 361 PHE PHE C . n 
C 1 155 GLU 155 362 362 GLU GLU C . n 
C 1 156 SER 156 363 363 SER SER C . n 
C 1 157 PHE 157 364 364 PHE PHE C . n 
C 1 158 VAL 158 365 365 VAL VAL C . n 
C 1 159 ASP 159 366 366 ASP ASP C . n 
C 1 160 TYR 160 367 367 TYR TYR C . n 
C 1 161 VAL 161 368 368 VAL VAL C . n 
C 1 162 ALA 162 369 369 ALA ALA C . n 
C 1 163 VAL 163 370 370 VAL VAL C . n 
C 1 164 GLU 164 371 371 GLU GLU C . n 
C 1 165 GLN 165 372 372 GLN GLN C . n 
C 1 166 LEU 166 373 373 LEU LEU C . n 
C 1 167 ASP 167 374 374 ASP ASP C . n 
C 1 168 GLY 168 375 375 GLY GLY C . n 
C 1 169 ASP 169 376 376 ASP ASP C . n 
C 1 170 ASN 170 377 377 ASN ASN C . n 
C 1 171 LYS 171 378 378 LYS LYS C . n 
C 1 172 TYR 172 379 379 TYR TYR C . n 
C 1 173 ASP 173 380 380 ASP ASP C . n 
C 1 174 ALA 174 381 381 ALA ALA C . n 
C 1 175 GLY 175 382 382 GLY GLY C . n 
C 1 176 GLU 176 383 383 GLU GLU C . n 
C 1 177 HIS 177 384 384 HIS HIS C . n 
C 1 178 GLY 178 385 385 GLY GLY C . n 
C 1 179 LEU 179 386 386 LEU LEU C . n 
C 1 180 GLN 180 387 387 GLN GLN C . n 
C 1 181 GLU 181 388 388 GLU GLU C . n 
C 1 182 ALA 182 389 389 ALA ALA C . n 
C 1 183 GLU 183 390 390 GLU GLU C . n 
C 1 184 LYS 184 391 391 LYS LYS C . n 
C 1 185 GLY 185 392 392 GLY GLY C . n 
C 1 186 VAL 186 393 393 VAL VAL C . n 
C 1 187 LYS 187 394 394 LYS LYS C . n 
C 1 188 PHE 188 395 395 PHE PHE C . n 
C 1 189 LEU 189 396 396 LEU LEU C . n 
C 1 190 THR 190 397 397 THR THR C . n 
C 1 191 LEU 191 398 398 LEU LEU C . n 
C 1 192 PRO 192 399 399 PRO PRO C . n 
C 1 193 PRO 193 400 400 PRO PRO C . n 
C 1 194 VAL 194 401 401 VAL VAL C . n 
C 1 195 LEU 195 402 402 LEU LEU C . n 
C 1 196 HIS 196 403 403 HIS HIS C . n 
C 1 197 LEU 197 404 404 LEU LEU C . n 
C 1 198 GLN 198 405 405 GLN GLN C . n 
C 1 199 LEU 199 406 406 LEU LEU C . n 
C 1 200 MET 200 407 407 MET MET C . n 
C 1 201 ARG 201 408 408 ARG ARG C . n 
C 1 202 PHE 202 409 409 PHE PHE C . n 
C 1 203 MET 203 410 ?   ?   ?   C . n 
C 1 204 TYR 204 411 ?   ?   ?   C . n 
C 1 205 ASP 205 412 ?   ?   ?   C . n 
C 1 206 PRO 206 413 ?   ?   ?   C . n 
C 1 207 GLN 207 414 ?   ?   ?   C . n 
C 1 208 THR 208 415 ?   ?   ?   C . n 
C 1 209 ASP 209 416 ?   ?   ?   C . n 
C 1 210 GLN 210 417 ?   ?   ?   C . n 
C 1 211 ASN 211 418 ?   ?   ?   C . n 
C 1 212 ILE 212 419 419 ILE ILE C . n 
C 1 213 LYS 213 420 420 LYS LYS C . n 
C 1 214 ILE 214 421 421 ILE ILE C . n 
C 1 215 ASN 215 422 422 ASN ASN C . n 
C 1 216 ASP 216 423 423 ASP ASP C . n 
C 1 217 ARG 217 424 424 ARG ARG C . n 
C 1 218 PHE 218 425 425 PHE PHE C . n 
C 1 219 GLU 219 426 426 GLU GLU C . n 
C 1 220 PHE 220 427 427 PHE PHE C . n 
C 1 221 PRO 221 428 428 PRO PRO C . n 
C 1 222 GLU 222 429 429 GLU GLU C . n 
C 1 223 GLN 223 430 430 GLN GLN C . n 
C 1 224 LEU 224 431 431 LEU LEU C . n 
C 1 225 PRO 225 432 432 PRO PRO C . n 
C 1 226 LEU 226 433 433 LEU LEU C . n 
C 1 227 ASP 227 434 434 ASP ASP C . n 
C 1 228 GLU 228 435 435 GLU GLU C . n 
C 1 229 PHE 229 436 436 PHE PHE C . n 
C 1 230 LEU 230 437 437 LEU LEU C . n 
C 1 231 GLN 231 438 438 GLN GLN C . n 
C 1 232 LYS 232 439 439 LYS LYS C . n 
C 1 233 THR 233 440 440 THR THR C . n 
C 1 234 ASP 234 441 441 ASP ASP C . n 
C 1 235 PRO 235 442 442 PRO PRO C . n 
C 1 236 LYS 236 443 443 LYS LYS C . n 
C 1 237 ASP 237 444 444 ASP ASP C . n 
C 1 238 PRO 238 445 445 PRO PRO C . n 
C 1 239 ALA 239 446 446 ALA ALA C . n 
C 1 240 ASN 240 447 447 ASN ASN C . n 
C 1 241 TYR 241 448 448 TYR TYR C . n 
C 1 242 ILE 242 449 449 ILE ILE C . n 
C 1 243 LEU 243 450 450 LEU LEU C . n 
C 1 244 HIS 244 451 451 HIS HIS C . n 
C 1 245 ALA 245 452 452 ALA ALA C . n 
C 1 246 VAL 246 453 453 VAL VAL C . n 
C 1 247 LEU 247 454 454 LEU LEU C . n 
C 1 248 VAL 248 455 455 VAL VAL C . n 
C 1 249 HIS 249 456 456 HIS HIS C . n 
C 1 250 SER 250 457 457 SER SER C . n 
C 1 251 GLY 251 458 458 GLY GLY C . n 
C 1 252 ASP 252 459 459 ASP ASP C . n 
C 1 253 ASN 253 460 460 ASN ASN C . n 
C 1 254 HIS 254 461 461 HIS HIS C . n 
C 1 255 GLY 255 462 462 GLY GLY C . n 
C 1 256 GLY 256 463 463 GLY GLY C . n 
C 1 257 HIS 257 464 464 HIS HIS C . n 
C 1 258 TYR 258 465 465 TYR TYR C . n 
C 1 259 VAL 259 466 466 VAL VAL C . n 
C 1 260 VAL 260 467 467 VAL VAL C . n 
C 1 261 TYR 261 468 468 TYR TYR C . n 
C 1 262 LEU 262 469 469 LEU LEU C . n 
C 1 263 ASN 263 470 470 ASN ASN C . n 
C 1 264 PRO 264 471 471 PRO PRO C . n 
C 1 265 LYS 265 472 472 LYS LYS C . n 
C 1 266 GLY 266 473 473 GLY GLY C . n 
C 1 267 ASP 267 474 474 ASP ASP C . n 
C 1 268 GLY 268 475 475 GLY GLY C . n 
C 1 269 LYS 269 476 476 LYS LYS C . n 
C 1 270 TRP 270 477 477 TRP TRP C . n 
C 1 271 CYS 271 478 478 CYS CYS C . n 
C 1 272 LYS 272 479 479 LYS LYS C . n 
C 1 273 PHE 273 480 480 PHE PHE C . n 
C 1 274 ASP 274 481 481 ASP ASP C . n 
C 1 275 ASP 275 482 482 ASP ASP C . n 
C 1 276 ASP 276 483 483 ASP ASP C . n 
C 1 277 VAL 277 484 484 VAL VAL C . n 
C 1 278 VAL 278 485 485 VAL VAL C . n 
C 1 279 SER 279 486 486 SER SER C . n 
C 1 280 ARG 280 487 487 ARG ARG C . n 
C 1 281 CYS 281 488 488 CYS CYS C . n 
C 1 282 THR 282 489 489 THR THR C . n 
C 1 283 LYS 283 490 490 LYS LYS C . n 
C 1 284 GLU 284 491 491 GLU GLU C . n 
C 1 285 GLU 285 492 492 GLU GLU C . n 
C 1 286 ALA 286 493 493 ALA ALA C . n 
C 1 287 ILE 287 494 494 ILE ILE C . n 
C 1 288 GLU 288 495 495 GLU GLU C . n 
C 1 289 HIS 289 496 496 HIS HIS C . n 
C 1 290 ASN 290 497 497 ASN ASN C . n 
C 1 291 TYR 291 498 498 TYR TYR C . n 
C 1 292 GLY 292 499 499 GLY GLY C . n 
C 1 293 GLY 293 500 ?   ?   ?   C . n 
C 1 294 HIS 294 501 ?   ?   ?   C . n 
C 1 295 ASP 295 502 ?   ?   ?   C . n 
C 1 296 ASP 296 503 ?   ?   ?   C . n 
C 1 297 ASP 297 504 ?   ?   ?   C . n 
C 1 298 LEU 298 505 ?   ?   ?   C . n 
C 1 299 SER 299 506 ?   ?   ?   C . n 
C 1 300 VAL 300 507 ?   ?   ?   C . n 
C 1 301 ARG 301 508 ?   ?   ?   C . n 
C 1 302 HIS 302 509 ?   ?   ?   C . n 
C 1 303 CYS 303 510 510 CYS CYS C . n 
C 1 304 THR 304 511 511 THR THR C . n 
C 1 305 ASN 305 512 512 ASN ASN C . n 
C 1 306 ALA 306 513 513 ALA ALA C . n 
C 1 307 TYR 307 514 514 TYR TYR C . n 
C 1 308 MET 308 515 515 MET MET C . n 
C 1 309 LEU 309 516 516 LEU LEU C . n 
C 1 310 VAL 310 517 517 VAL VAL C . n 
C 1 311 TYR 311 518 518 TYR TYR C . n 
C 1 312 ILE 312 519 519 ILE ILE C . n 
C 1 313 ARG 313 520 520 ARG ARG C . n 
C 1 314 GLU 314 521 521 GLU GLU C . n 
C 1 315 SER 315 522 522 SER SER C . n 
C 1 316 LYS 316 523 523 LYS LYS C . n 
C 1 317 LEU 317 524 524 LEU LEU C . n 
C 1 318 SER 318 525 525 SER SER C . n 
C 1 319 GLU 319 526 526 GLU GLU C . n 
C 1 320 VAL 320 527 527 VAL VAL C . n 
C 1 321 LEU 321 528 528 LEU LEU C . n 
C 1 322 GLN 322 529 529 GLN GLN C . n 
C 1 323 ALA 323 530 530 ALA ALA C . n 
C 1 324 VAL 324 531 531 VAL VAL C . n 
C 1 325 THR 325 532 532 THR THR C . n 
C 1 326 ASP 326 533 533 ASP ASP C . n 
C 1 327 HIS 327 534 534 HIS HIS C . n 
C 1 328 ASP 328 535 535 ASP ASP C . n 
C 1 329 ILE 329 536 536 ILE ILE C . n 
C 1 330 PRO 330 537 ?   ?   ?   C . n 
C 1 331 GLN 331 538 ?   ?   ?   C . n 
C 1 332 GLN 332 539 ?   ?   ?   C . n 
C 1 333 LEU 333 540 ?   ?   ?   C . n 
C 1 334 VAL 334 541 ?   ?   ?   C . n 
C 1 335 GLU 335 542 ?   ?   ?   C . n 
C 1 336 ARG 336 543 ?   ?   ?   C . n 
C 1 337 LEU 337 544 ?   ?   ?   C . n 
C 1 338 GLN 338 545 ?   ?   ?   C . n 
C 1 339 GLU 339 546 ?   ?   ?   C . n 
C 1 340 GLU 340 547 ?   ?   ?   C . n 
C 1 341 LYS 341 548 ?   ?   ?   C . n 
C 1 342 ARG 342 549 ?   ?   ?   C . n 
C 1 343 ILE 343 550 ?   ?   ?   C . n 
C 1 344 GLU 344 551 ?   ?   ?   C . n 
C 1 345 ALA 345 552 ?   ?   ?   C . n 
C 1 346 GLN 346 553 ?   ?   ?   C . n 
C 1 347 LYS 347 554 ?   ?   ?   C . n 
C 1 348 ARG 348 555 ?   ?   ?   C . n 
C 1 349 LYS 349 556 ?   ?   ?   C . n 
C 1 350 GLU 350 557 ?   ?   ?   C . n 
C 1 351 ARG 351 558 ?   ?   ?   C . n 
C 1 352 GLN 352 559 ?   ?   ?   C . n 
C 1 353 GLU 353 560 ?   ?   ?   C . n 
D 2 1   MET 1   1   1   MET MET D . n 
D 2 2   GLN 2   2   2   GLN GLN D . n 
D 2 3   ILE 3   3   3   ILE ILE D . n 
D 2 4   PHE 4   4   4   PHE PHE D . n 
D 2 5   VAL 5   5   5   VAL VAL D . n 
D 2 6   LYS 6   6   6   LYS LYS D . n 
D 2 7   THR 7   7   7   THR THR D . n 
D 2 8   LEU 8   8   8   LEU LEU D . n 
D 2 9   THR 9   9   9   THR THR D . n 
D 2 10  GLY 10  10  10  GLY GLY D . n 
D 2 11  LYS 11  11  11  LYS LYS D . n 
D 2 12  THR 12  12  12  THR THR D . n 
D 2 13  ILE 13  13  13  ILE ILE D . n 
D 2 14  THR 14  14  14  THR THR D . n 
D 2 15  LEU 15  15  15  LEU LEU D . n 
D 2 16  GLU 16  16  16  GLU GLU D . n 
D 2 17  VAL 17  17  17  VAL VAL D . n 
D 2 18  GLU 18  18  18  GLU GLU D . n 
D 2 19  PRO 19  19  19  PRO PRO D . n 
D 2 20  SER 20  20  20  SER SER D . n 
D 2 21  ASP 21  21  21  ASP ASP D . n 
D 2 22  THR 22  22  22  THR THR D . n 
D 2 23  ILE 23  23  23  ILE ILE D . n 
D 2 24  GLU 24  24  24  GLU GLU D . n 
D 2 25  ASN 25  25  25  ASN ASN D . n 
D 2 26  VAL 26  26  26  VAL VAL D . n 
D 2 27  LYS 27  27  27  LYS LYS D . n 
D 2 28  ALA 28  28  28  ALA ALA D . n 
D 2 29  LYS 29  29  29  LYS LYS D . n 
D 2 30  ILE 30  30  30  ILE ILE D . n 
D 2 31  GLN 31  31  31  GLN GLN D . n 
D 2 32  ASP 32  32  32  ASP ASP D . n 
D 2 33  LYS 33  33  33  LYS LYS D . n 
D 2 34  GLU 34  34  34  GLU GLU D . n 
D 2 35  GLY 35  35  35  GLY GLY D . n 
D 2 36  ILE 36  36  36  ILE ILE D . n 
D 2 37  PRO 37  37  37  PRO PRO D . n 
D 2 38  PRO 38  38  38  PRO PRO D . n 
D 2 39  ASP 39  39  39  ASP ASP D . n 
D 2 40  GLN 40  40  40  GLN GLN D . n 
D 2 41  GLN 41  41  41  GLN GLN D . n 
D 2 42  ARG 42  42  42  ARG ARG D . n 
D 2 43  LEU 43  43  43  LEU LEU D . n 
D 2 44  ILE 44  44  44  ILE ILE D . n 
D 2 45  PHE 45  45  45  PHE PHE D . n 
D 2 46  ALA 46  46  46  ALA ALA D . n 
D 2 47  GLY 47  47  47  GLY GLY D . n 
D 2 48  LYS 48  48  48  LYS LYS D . n 
D 2 49  GLN 49  49  49  GLN GLN D . n 
D 2 50  LEU 50  50  50  LEU LEU D . n 
D 2 51  GLU 51  51  51  GLU GLU D . n 
D 2 52  ASP 52  52  52  ASP ASP D . n 
D 2 53  GLY 53  53  53  GLY GLY D . n 
D 2 54  ARG 54  54  54  ARG ARG D . n 
D 2 55  THR 55  55  55  THR THR D . n 
D 2 56  LEU 56  56  56  LEU LEU D . n 
D 2 57  SER 57  57  57  SER SER D . n 
D 2 58  ASP 58  58  58  ASP ASP D . n 
D 2 59  TYR 59  59  59  TYR TYR D . n 
D 2 60  ASN 60  60  60  ASN ASN D . n 
D 2 61  ILE 61  61  61  ILE ILE D . n 
D 2 62  GLN 62  62  62  GLN GLN D . n 
D 2 63  LYS 63  63  63  LYS LYS D . n 
D 2 64  GLU 64  64  64  GLU GLU D . n 
D 2 65  SER 65  65  65  SER SER D . n 
D 2 66  THR 66  66  66  THR THR D . n 
D 2 67  LEU 67  67  67  LEU LEU D . n 
D 2 68  HIS 68  68  68  HIS HIS D . n 
D 2 69  LEU 69  69  69  LEU LEU D . n 
D 2 70  VAL 70  70  70  VAL VAL D . n 
D 2 71  LEU 71  71  71  LEU LEU D . n 
D 2 72  ARG 72  72  72  ARG ARG D . n 
D 2 73  LEU 73  73  73  LEU LEU D . n 
D 2 74  ARG 74  74  74  ARG ARG D . n 
D 2 75  GLY 75  75  75  GLY GLY D . n 
E 1 1   LYS 1   208 ?   ?   ?   E . n 
E 1 2   LYS 2   209 ?   ?   ?   E . n 
E 1 3   HIS 3   210 ?   ?   ?   E . n 
E 1 4   THR 4   211 ?   ?   ?   E . n 
E 1 5   GLY 5   212 212 GLY GLY E . n 
E 1 6   TYR 6   213 213 TYR TYR E . n 
E 1 7   VAL 7   214 214 VAL VAL E . n 
E 1 8   GLY 8   215 215 GLY GLY E . n 
E 1 9   LEU 9   216 216 LEU LEU E . n 
E 1 10  LYS 10  217 217 LYS LYS E . n 
E 1 11  ASN 11  218 218 ASN ASN E . n 
E 1 12  GLN 12  219 219 GLN GLN E . n 
E 1 13  GLY 13  220 220 GLY GLY E . n 
E 1 14  ALA 14  221 221 ALA ALA E . n 
E 1 15  THR 15  222 222 THR THR E . n 
E 1 16  CYS 16  223 223 CYS CYS E . n 
E 1 17  TYR 17  224 224 TYR TYR E . n 
E 1 18  MET 18  225 225 MET MET E . n 
E 1 19  ASN 19  226 226 ASN ASN E . n 
E 1 20  SER 20  227 227 SER SER E . n 
E 1 21  LEU 21  228 228 LEU LEU E . n 
E 1 22  LEU 22  229 229 LEU LEU E . n 
E 1 23  GLN 23  230 230 GLN GLN E . n 
E 1 24  THR 24  231 231 THR THR E . n 
E 1 25  LEU 25  232 232 LEU LEU E . n 
E 1 26  PHE 26  233 233 PHE PHE E . n 
E 1 27  PHE 27  234 234 PHE PHE E . n 
E 1 28  THR 28  235 235 THR THR E . n 
E 1 29  ASN 29  236 236 ASN ASN E . n 
E 1 30  GLN 30  237 237 GLN GLN E . n 
E 1 31  LEU 31  238 238 LEU LEU E . n 
E 1 32  ARG 32  239 239 ARG ARG E . n 
E 1 33  LYS 33  240 240 LYS LYS E . n 
E 1 34  ALA 34  241 241 ALA ALA E . n 
E 1 35  VAL 35  242 242 VAL VAL E . n 
E 1 36  TYR 36  243 243 TYR TYR E . n 
E 1 37  MET 37  244 244 MET MET E . n 
E 1 38  MET 38  245 245 MET MET E . n 
E 1 39  PRO 39  246 246 PRO PRO E . n 
E 1 40  THR 40  247 247 THR THR E . n 
E 1 41  GLU 41  248 248 GLU GLU E . n 
E 1 42  GLY 42  249 249 GLY GLY E . n 
E 1 43  ASP 43  250 ?   ?   ?   E . n 
E 1 44  ASP 44  251 ?   ?   ?   E . n 
E 1 45  SER 45  252 252 SER SER E . n 
E 1 46  SER 46  253 253 SER SER E . n 
E 1 47  LYS 47  254 254 LYS LYS E . n 
E 1 48  SER 48  255 255 SER SER E . n 
E 1 49  VAL 49  256 256 VAL VAL E . n 
E 1 50  PRO 50  257 257 PRO PRO E . n 
E 1 51  LEU 51  258 258 LEU LEU E . n 
E 1 52  ALA 52  259 259 ALA ALA E . n 
E 1 53  LEU 53  260 260 LEU LEU E . n 
E 1 54  GLN 54  261 261 GLN GLN E . n 
E 1 55  ARG 55  262 262 ARG ARG E . n 
E 1 56  VAL 56  263 263 VAL VAL E . n 
E 1 57  PHE 57  264 264 PHE PHE E . n 
E 1 58  TYR 58  265 265 TYR TYR E . n 
E 1 59  GLU 59  266 266 GLU GLU E . n 
E 1 60  LEU 60  267 267 LEU LEU E . n 
E 1 61  GLN 61  268 268 GLN GLN E . n 
E 1 62  HIS 62  269 269 HIS HIS E . n 
E 1 63  SER 63  270 270 SER SER E . n 
E 1 64  ASP 64  271 271 ASP ASP E . n 
E 1 65  LYS 65  272 272 LYS LYS E . n 
E 1 66  PRO 66  273 273 PRO PRO E . n 
E 1 67  VAL 67  274 274 VAL VAL E . n 
E 1 68  GLY 68  275 275 GLY GLY E . n 
E 1 69  THR 69  276 276 THR THR E . n 
E 1 70  LYS 70  277 277 LYS LYS E . n 
E 1 71  LYS 71  278 278 LYS LYS E . n 
E 1 72  LEU 72  279 279 LEU LEU E . n 
E 1 73  THR 73  280 280 THR THR E . n 
E 1 74  LYS 74  281 281 LYS LYS E . n 
E 1 75  SER 75  282 282 SER SER E . n 
E 1 76  PHE 76  283 283 PHE PHE E . n 
E 1 77  GLY 77  284 284 GLY GLY E . n 
E 1 78  TRP 78  285 285 TRP TRP E . n 
E 1 79  GLU 79  286 286 GLU GLU E . n 
E 1 80  THR 80  287 287 THR THR E . n 
E 1 81  LEU 81  288 288 LEU LEU E . n 
E 1 82  ASP 82  289 289 ASP ASP E . n 
E 1 83  SER 83  290 290 SER SER E . n 
E 1 84  PHE 84  291 291 PHE PHE E . n 
E 1 85  MET 85  292 292 MET MET E . n 
E 1 86  GLN 86  293 293 GLN GLN E . n 
E 1 87  HIS 87  294 294 HIS HIS E . n 
E 1 88  ASP 88  295 295 ASP ASP E . n 
E 1 89  VAL 89  296 296 VAL VAL E . n 
E 1 90  GLN 90  297 297 GLN GLN E . n 
E 1 91  GLU 91  298 298 GLU GLU E . n 
E 1 92  LEU 92  299 299 LEU LEU E . n 
E 1 93  CYS 93  300 300 CYS CYS E . n 
E 1 94  ARG 94  301 301 ARG ARG E . n 
E 1 95  VAL 95  302 302 VAL VAL E . n 
E 1 96  LEU 96  303 303 LEU LEU E . n 
E 1 97  LEU 97  304 304 LEU LEU E . n 
E 1 98  ASP 98  305 305 ASP ASP E . n 
E 1 99  ASN 99  306 306 ASN ASN E . n 
E 1 100 VAL 100 307 307 VAL VAL E . n 
E 1 101 GLU 101 308 308 GLU GLU E . n 
E 1 102 ASN 102 309 309 ASN ASN E . n 
E 1 103 LYS 103 310 310 LYS LYS E . n 
E 1 104 MET 104 311 311 MET MET E . n 
E 1 105 LYS 105 312 312 LYS LYS E . n 
E 1 106 GLY 106 313 313 GLY GLY E . n 
E 1 107 THR 107 314 314 THR THR E . n 
E 1 108 CYS 108 315 315 CYS CYS E . n 
E 1 109 VAL 109 316 316 VAL VAL E . n 
E 1 110 GLU 110 317 317 GLU GLU E . n 
E 1 111 GLY 111 318 318 GLY GLY E . n 
E 1 112 THR 112 319 319 THR THR E . n 
E 1 113 ILE 113 320 320 ILE ILE E . n 
E 1 114 PRO 114 321 321 PRO PRO E . n 
E 1 115 LYS 115 322 322 LYS LYS E . n 
E 1 116 LEU 116 323 323 LEU LEU E . n 
E 1 117 PHE 117 324 324 PHE PHE E . n 
E 1 118 ARG 118 325 325 ARG ARG E . n 
E 1 119 GLY 119 326 326 GLY GLY E . n 
E 1 120 LYS 120 327 327 LYS LYS E . n 
E 1 121 MET 121 328 328 MET MET E . n 
E 1 122 VAL 122 329 329 VAL VAL E . n 
E 1 123 SER 123 330 330 SER SER E . n 
E 1 124 TYR 124 331 331 TYR TYR E . n 
E 1 125 ILE 125 332 332 ILE ILE E . n 
E 1 126 GLN 126 333 333 GLN GLN E . n 
E 1 127 CYS 127 334 334 CYS CYS E . n 
E 1 128 LYS 128 335 335 LYS LYS E . n 
E 1 129 GLU 129 336 336 GLU GLU E . n 
E 1 130 VAL 130 337 337 VAL VAL E . n 
E 1 131 ASP 131 338 338 ASP ASP E . n 
E 1 132 TYR 132 339 339 TYR TYR E . n 
E 1 133 ARG 133 340 340 ARG ARG E . n 
E 1 134 SER 134 341 341 SER SER E . n 
E 1 135 ASP 135 342 342 ASP ASP E . n 
E 1 136 ARG 136 343 343 ARG ARG E . n 
E 1 137 ARG 137 344 344 ARG ARG E . n 
E 1 138 GLU 138 345 345 GLU GLU E . n 
E 1 139 ASP 139 346 346 ASP ASP E . n 
E 1 140 TYR 140 347 347 TYR TYR E . n 
E 1 141 TYR 141 348 348 TYR TYR E . n 
E 1 142 ASP 142 349 349 ASP ASP E . n 
E 1 143 ILE 143 350 350 ILE ILE E . n 
E 1 144 GLN 144 351 351 GLN GLN E . n 
E 1 145 LEU 145 352 352 LEU LEU E . n 
E 1 146 SER 146 353 353 SER SER E . n 
E 1 147 ILE 147 354 354 ILE ILE E . n 
E 1 148 LYS 148 355 355 LYS LYS E . n 
E 1 149 GLY 149 356 356 GLY GLY E . n 
E 1 150 LYS 150 357 357 LYS LYS E . n 
E 1 151 LYS 151 358 358 LYS LYS E . n 
E 1 152 ASN 152 359 359 ASN ASN E . n 
E 1 153 ILE 153 360 360 ILE ILE E . n 
E 1 154 PHE 154 361 361 PHE PHE E . n 
E 1 155 GLU 155 362 362 GLU GLU E . n 
E 1 156 SER 156 363 363 SER SER E . n 
E 1 157 PHE 157 364 364 PHE PHE E . n 
E 1 158 VAL 158 365 365 VAL VAL E . n 
E 1 159 ASP 159 366 366 ASP ASP E . n 
E 1 160 TYR 160 367 367 TYR TYR E . n 
E 1 161 VAL 161 368 368 VAL VAL E . n 
E 1 162 ALA 162 369 369 ALA ALA E . n 
E 1 163 VAL 163 370 370 VAL VAL E . n 
E 1 164 GLU 164 371 371 GLU GLU E . n 
E 1 165 GLN 165 372 372 GLN GLN E . n 
E 1 166 LEU 166 373 373 LEU LEU E . n 
E 1 167 ASP 167 374 374 ASP ASP E . n 
E 1 168 GLY 168 375 375 GLY GLY E . n 
E 1 169 ASP 169 376 376 ASP ASP E . n 
E 1 170 ASN 170 377 377 ASN ASN E . n 
E 1 171 LYS 171 378 378 LYS LYS E . n 
E 1 172 TYR 172 379 379 TYR TYR E . n 
E 1 173 ASP 173 380 380 ASP ASP E . n 
E 1 174 ALA 174 381 381 ALA ALA E . n 
E 1 175 GLY 175 382 382 GLY GLY E . n 
E 1 176 GLU 176 383 383 GLU GLU E . n 
E 1 177 HIS 177 384 384 HIS HIS E . n 
E 1 178 GLY 178 385 385 GLY GLY E . n 
E 1 179 LEU 179 386 386 LEU LEU E . n 
E 1 180 GLN 180 387 387 GLN GLN E . n 
E 1 181 GLU 181 388 388 GLU GLU E . n 
E 1 182 ALA 182 389 389 ALA ALA E . n 
E 1 183 GLU 183 390 390 GLU GLU E . n 
E 1 184 LYS 184 391 391 LYS LYS E . n 
E 1 185 GLY 185 392 392 GLY GLY E . n 
E 1 186 VAL 186 393 393 VAL VAL E . n 
E 1 187 LYS 187 394 394 LYS LYS E . n 
E 1 188 PHE 188 395 395 PHE PHE E . n 
E 1 189 LEU 189 396 396 LEU LEU E . n 
E 1 190 THR 190 397 397 THR THR E . n 
E 1 191 LEU 191 398 398 LEU LEU E . n 
E 1 192 PRO 192 399 399 PRO PRO E . n 
E 1 193 PRO 193 400 400 PRO PRO E . n 
E 1 194 VAL 194 401 401 VAL VAL E . n 
E 1 195 LEU 195 402 402 LEU LEU E . n 
E 1 196 HIS 196 403 403 HIS HIS E . n 
E 1 197 LEU 197 404 404 LEU LEU E . n 
E 1 198 GLN 198 405 405 GLN GLN E . n 
E 1 199 LEU 199 406 406 LEU LEU E . n 
E 1 200 MET 200 407 407 MET MET E . n 
E 1 201 ARG 201 408 408 ARG ARG E . n 
E 1 202 PHE 202 409 409 PHE PHE E . n 
E 1 203 MET 203 410 410 MET MET E . n 
E 1 204 TYR 204 411 411 TYR TYR E . n 
E 1 205 ASP 205 412 ?   ?   ?   E . n 
E 1 206 PRO 206 413 ?   ?   ?   E . n 
E 1 207 GLN 207 414 ?   ?   ?   E . n 
E 1 208 THR 208 415 ?   ?   ?   E . n 
E 1 209 ASP 209 416 ?   ?   ?   E . n 
E 1 210 GLN 210 417 417 GLN GLN E . n 
E 1 211 ASN 211 418 418 ASN ASN E . n 
E 1 212 ILE 212 419 419 ILE ILE E . n 
E 1 213 LYS 213 420 420 LYS LYS E . n 
E 1 214 ILE 214 421 421 ILE ILE E . n 
E 1 215 ASN 215 422 422 ASN ASN E . n 
E 1 216 ASP 216 423 423 ASP ASP E . n 
E 1 217 ARG 217 424 424 ARG ARG E . n 
E 1 218 PHE 218 425 425 PHE PHE E . n 
E 1 219 GLU 219 426 426 GLU GLU E . n 
E 1 220 PHE 220 427 427 PHE PHE E . n 
E 1 221 PRO 221 428 428 PRO PRO E . n 
E 1 222 GLU 222 429 429 GLU GLU E . n 
E 1 223 GLN 223 430 430 GLN GLN E . n 
E 1 224 LEU 224 431 431 LEU LEU E . n 
E 1 225 PRO 225 432 432 PRO PRO E . n 
E 1 226 LEU 226 433 433 LEU LEU E . n 
E 1 227 ASP 227 434 434 ASP ASP E . n 
E 1 228 GLU 228 435 435 GLU GLU E . n 
E 1 229 PHE 229 436 436 PHE PHE E . n 
E 1 230 LEU 230 437 437 LEU LEU E . n 
E 1 231 GLN 231 438 438 GLN GLN E . n 
E 1 232 LYS 232 439 439 LYS LYS E . n 
E 1 233 THR 233 440 440 THR THR E . n 
E 1 234 ASP 234 441 441 ASP ASP E . n 
E 1 235 PRO 235 442 442 PRO PRO E . n 
E 1 236 LYS 236 443 443 LYS LYS E . n 
E 1 237 ASP 237 444 444 ASP ASP E . n 
E 1 238 PRO 238 445 445 PRO PRO E . n 
E 1 239 ALA 239 446 446 ALA ALA E . n 
E 1 240 ASN 240 447 447 ASN ASN E . n 
E 1 241 TYR 241 448 448 TYR TYR E . n 
E 1 242 ILE 242 449 449 ILE ILE E . n 
E 1 243 LEU 243 450 450 LEU LEU E . n 
E 1 244 HIS 244 451 451 HIS HIS E . n 
E 1 245 ALA 245 452 452 ALA ALA E . n 
E 1 246 VAL 246 453 453 VAL VAL E . n 
E 1 247 LEU 247 454 454 LEU LEU E . n 
E 1 248 VAL 248 455 455 VAL VAL E . n 
E 1 249 HIS 249 456 456 HIS HIS E . n 
E 1 250 SER 250 457 457 SER SER E . n 
E 1 251 GLY 251 458 458 GLY GLY E . n 
E 1 252 ASP 252 459 459 ASP ASP E . n 
E 1 253 ASN 253 460 ?   ?   ?   E . n 
E 1 254 HIS 254 461 461 HIS HIS E . n 
E 1 255 GLY 255 462 462 GLY GLY E . n 
E 1 256 GLY 256 463 463 GLY GLY E . n 
E 1 257 HIS 257 464 464 HIS HIS E . n 
E 1 258 TYR 258 465 465 TYR TYR E . n 
E 1 259 VAL 259 466 466 VAL VAL E . n 
E 1 260 VAL 260 467 467 VAL VAL E . n 
E 1 261 TYR 261 468 468 TYR TYR E . n 
E 1 262 LEU 262 469 469 LEU LEU E . n 
E 1 263 ASN 263 470 470 ASN ASN E . n 
E 1 264 PRO 264 471 471 PRO PRO E . n 
E 1 265 LYS 265 472 472 LYS LYS E . n 
E 1 266 GLY 266 473 473 GLY GLY E . n 
E 1 267 ASP 267 474 474 ASP ASP E . n 
E 1 268 GLY 268 475 475 GLY GLY E . n 
E 1 269 LYS 269 476 476 LYS LYS E . n 
E 1 270 TRP 270 477 477 TRP TRP E . n 
E 1 271 CYS 271 478 478 CYS CYS E . n 
E 1 272 LYS 272 479 479 LYS LYS E . n 
E 1 273 PHE 273 480 480 PHE PHE E . n 
E 1 274 ASP 274 481 481 ASP ASP E . n 
E 1 275 ASP 275 482 482 ASP ASP E . n 
E 1 276 ASP 276 483 483 ASP ASP E . n 
E 1 277 VAL 277 484 484 VAL VAL E . n 
E 1 278 VAL 278 485 485 VAL VAL E . n 
E 1 279 SER 279 486 486 SER SER E . n 
E 1 280 ARG 280 487 487 ARG ARG E . n 
E 1 281 CYS 281 488 488 CYS CYS E . n 
E 1 282 THR 282 489 489 THR THR E . n 
E 1 283 LYS 283 490 490 LYS LYS E . n 
E 1 284 GLU 284 491 491 GLU GLU E . n 
E 1 285 GLU 285 492 492 GLU GLU E . n 
E 1 286 ALA 286 493 493 ALA ALA E . n 
E 1 287 ILE 287 494 494 ILE ILE E . n 
E 1 288 GLU 288 495 495 GLU GLU E . n 
E 1 289 HIS 289 496 496 HIS HIS E . n 
E 1 290 ASN 290 497 497 ASN ASN E . n 
E 1 291 TYR 291 498 498 TYR TYR E . n 
E 1 292 GLY 292 499 499 GLY GLY E . n 
E 1 293 GLY 293 500 500 GLY GLY E . n 
E 1 294 HIS 294 501 ?   ?   ?   E . n 
E 1 295 ASP 295 502 ?   ?   ?   E . n 
E 1 296 ASP 296 503 ?   ?   ?   E . n 
E 1 297 ASP 297 504 ?   ?   ?   E . n 
E 1 298 LEU 298 505 ?   ?   ?   E . n 
E 1 299 SER 299 506 ?   ?   ?   E . n 
E 1 300 VAL 300 507 ?   ?   ?   E . n 
E 1 301 ARG 301 508 508 ARG ARG E . n 
E 1 302 HIS 302 509 509 HIS HIS E . n 
E 1 303 CYS 303 510 510 CYS CYS E . n 
E 1 304 THR 304 511 511 THR THR E . n 
E 1 305 ASN 305 512 512 ASN ASN E . n 
E 1 306 ALA 306 513 513 ALA ALA E . n 
E 1 307 TYR 307 514 514 TYR TYR E . n 
E 1 308 MET 308 515 515 MET MET E . n 
E 1 309 LEU 309 516 516 LEU LEU E . n 
E 1 310 VAL 310 517 517 VAL VAL E . n 
E 1 311 TYR 311 518 518 TYR TYR E . n 
E 1 312 ILE 312 519 519 ILE ILE E . n 
E 1 313 ARG 313 520 520 ARG ARG E . n 
E 1 314 GLU 314 521 521 GLU GLU E . n 
E 1 315 SER 315 522 522 SER SER E . n 
E 1 316 LYS 316 523 523 LYS LYS E . n 
E 1 317 LEU 317 524 524 LEU LEU E . n 
E 1 318 SER 318 525 525 SER SER E . n 
E 1 319 GLU 319 526 526 GLU GLU E . n 
E 1 320 VAL 320 527 527 VAL VAL E . n 
E 1 321 LEU 321 528 528 LEU LEU E . n 
E 1 322 GLN 322 529 529 GLN GLN E . n 
E 1 323 ALA 323 530 530 ALA ALA E . n 
E 1 324 VAL 324 531 531 VAL VAL E . n 
E 1 325 THR 325 532 532 THR THR E . n 
E 1 326 ASP 326 533 533 ASP ASP E . n 
E 1 327 HIS 327 534 534 HIS HIS E . n 
E 1 328 ASP 328 535 535 ASP ASP E . n 
E 1 329 ILE 329 536 536 ILE ILE E . n 
E 1 330 PRO 330 537 537 PRO PRO E . n 
E 1 331 GLN 331 538 538 GLN GLN E . n 
E 1 332 GLN 332 539 539 GLN GLN E . n 
E 1 333 LEU 333 540 540 LEU LEU E . n 
E 1 334 VAL 334 541 541 VAL VAL E . n 
E 1 335 GLU 335 542 542 GLU GLU E . n 
E 1 336 ARG 336 543 543 ARG ARG E . n 
E 1 337 LEU 337 544 544 LEU LEU E . n 
E 1 338 GLN 338 545 545 GLN GLN E . n 
E 1 339 GLU 339 546 546 GLU GLU E . n 
E 1 340 GLU 340 547 547 GLU GLU E . n 
E 1 341 LYS 341 548 ?   ?   ?   E . n 
E 1 342 ARG 342 549 ?   ?   ?   E . n 
E 1 343 ILE 343 550 ?   ?   ?   E . n 
E 1 344 GLU 344 551 ?   ?   ?   E . n 
E 1 345 ALA 345 552 ?   ?   ?   E . n 
E 1 346 GLN 346 553 ?   ?   ?   E . n 
E 1 347 LYS 347 554 ?   ?   ?   E . n 
E 1 348 ARG 348 555 ?   ?   ?   E . n 
E 1 349 LYS 349 556 ?   ?   ?   E . n 
E 1 350 GLU 350 557 ?   ?   ?   E . n 
E 1 351 ARG 351 558 ?   ?   ?   E . n 
E 1 352 GLN 352 559 ?   ?   ?   E . n 
E 1 353 GLU 353 560 ?   ?   ?   E . n 
F 2 1   MET 1   1   1   MET MET F . n 
F 2 2   GLN 2   2   2   GLN GLN F . n 
F 2 3   ILE 3   3   3   ILE ILE F . n 
F 2 4   PHE 4   4   4   PHE PHE F . n 
F 2 5   VAL 5   5   5   VAL VAL F . n 
F 2 6   LYS 6   6   6   LYS LYS F . n 
F 2 7   THR 7   7   7   THR THR F . n 
F 2 8   LEU 8   8   8   LEU LEU F . n 
F 2 9   THR 9   9   9   THR THR F . n 
F 2 10  GLY 10  10  10  GLY GLY F . n 
F 2 11  LYS 11  11  11  LYS LYS F . n 
F 2 12  THR 12  12  12  THR THR F . n 
F 2 13  ILE 13  13  13  ILE ILE F . n 
F 2 14  THR 14  14  14  THR THR F . n 
F 2 15  LEU 15  15  15  LEU LEU F . n 
F 2 16  GLU 16  16  16  GLU GLU F . n 
F 2 17  VAL 17  17  17  VAL VAL F . n 
F 2 18  GLU 18  18  18  GLU GLU F . n 
F 2 19  PRO 19  19  19  PRO PRO F . n 
F 2 20  SER 20  20  20  SER SER F . n 
F 2 21  ASP 21  21  21  ASP ASP F . n 
F 2 22  THR 22  22  22  THR THR F . n 
F 2 23  ILE 23  23  23  ILE ILE F . n 
F 2 24  GLU 24  24  24  GLU GLU F . n 
F 2 25  ASN 25  25  25  ASN ASN F . n 
F 2 26  VAL 26  26  26  VAL VAL F . n 
F 2 27  LYS 27  27  27  LYS LYS F . n 
F 2 28  ALA 28  28  28  ALA ALA F . n 
F 2 29  LYS 29  29  29  LYS LYS F . n 
F 2 30  ILE 30  30  30  ILE ILE F . n 
F 2 31  GLN 31  31  31  GLN GLN F . n 
F 2 32  ASP 32  32  32  ASP ASP F . n 
F 2 33  LYS 33  33  33  LYS LYS F . n 
F 2 34  GLU 34  34  34  GLU GLU F . n 
F 2 35  GLY 35  35  35  GLY GLY F . n 
F 2 36  ILE 36  36  36  ILE ILE F . n 
F 2 37  PRO 37  37  37  PRO PRO F . n 
F 2 38  PRO 38  38  38  PRO PRO F . n 
F 2 39  ASP 39  39  39  ASP ASP F . n 
F 2 40  GLN 40  40  40  GLN GLN F . n 
F 2 41  GLN 41  41  41  GLN GLN F . n 
F 2 42  ARG 42  42  42  ARG ARG F . n 
F 2 43  LEU 43  43  43  LEU LEU F . n 
F 2 44  ILE 44  44  44  ILE ILE F . n 
F 2 45  PHE 45  45  45  PHE PHE F . n 
F 2 46  ALA 46  46  46  ALA ALA F . n 
F 2 47  GLY 47  47  47  GLY GLY F . n 
F 2 48  LYS 48  48  48  LYS LYS F . n 
F 2 49  GLN 49  49  49  GLN GLN F . n 
F 2 50  LEU 50  50  50  LEU LEU F . n 
F 2 51  GLU 51  51  51  GLU GLU F . n 
F 2 52  ASP 52  52  52  ASP ASP F . n 
F 2 53  GLY 53  53  53  GLY GLY F . n 
F 2 54  ARG 54  54  54  ARG ARG F . n 
F 2 55  THR 55  55  55  THR THR F . n 
F 2 56  LEU 56  56  56  LEU LEU F . n 
F 2 57  SER 57  57  57  SER SER F . n 
F 2 58  ASP 58  58  58  ASP ASP F . n 
F 2 59  TYR 59  59  59  TYR TYR F . n 
F 2 60  ASN 60  60  60  ASN ASN F . n 
F 2 61  ILE 61  61  61  ILE ILE F . n 
F 2 62  GLN 62  62  62  GLN GLN F . n 
F 2 63  LYS 63  63  63  LYS LYS F . n 
F 2 64  GLU 64  64  64  GLU GLU F . n 
F 2 65  SER 65  65  65  SER SER F . n 
F 2 66  THR 66  66  66  THR THR F . n 
F 2 67  LEU 67  67  67  LEU LEU F . n 
F 2 68  HIS 68  68  68  HIS HIS F . n 
F 2 69  LEU 69  69  69  LEU LEU F . n 
F 2 70  VAL 70  70  70  VAL VAL F . n 
F 2 71  LEU 71  71  71  LEU LEU F . n 
F 2 72  ARG 72  72  72  ARG ARG F . n 
F 2 73  LEU 73  73  73  LEU LEU F . n 
F 2 74  ARG 74  74  74  ARG ARG F . n 
F 2 75  GLY 75  75  75  GLY GLY F . n 
G 1 1   LYS 1   208 ?   ?   ?   G . n 
G 1 2   LYS 2   209 ?   ?   ?   G . n 
G 1 3   HIS 3   210 ?   ?   ?   G . n 
G 1 4   THR 4   211 ?   ?   ?   G . n 
G 1 5   GLY 5   212 ?   ?   ?   G . n 
G 1 6   TYR 6   213 213 TYR TYR G . n 
G 1 7   VAL 7   214 214 VAL VAL G . n 
G 1 8   GLY 8   215 215 GLY GLY G . n 
G 1 9   LEU 9   216 216 LEU LEU G . n 
G 1 10  LYS 10  217 217 LYS LYS G . n 
G 1 11  ASN 11  218 218 ASN ASN G . n 
G 1 12  GLN 12  219 219 GLN GLN G . n 
G 1 13  GLY 13  220 220 GLY GLY G . n 
G 1 14  ALA 14  221 221 ALA ALA G . n 
G 1 15  THR 15  222 222 THR THR G . n 
G 1 16  CYS 16  223 223 CYS CYS G . n 
G 1 17  TYR 17  224 224 TYR TYR G . n 
G 1 18  MET 18  225 225 MET MET G . n 
G 1 19  ASN 19  226 226 ASN ASN G . n 
G 1 20  SER 20  227 227 SER SER G . n 
G 1 21  LEU 21  228 228 LEU LEU G . n 
G 1 22  LEU 22  229 229 LEU LEU G . n 
G 1 23  GLN 23  230 230 GLN GLN G . n 
G 1 24  THR 24  231 231 THR THR G . n 
G 1 25  LEU 25  232 232 LEU LEU G . n 
G 1 26  PHE 26  233 233 PHE PHE G . n 
G 1 27  PHE 27  234 234 PHE PHE G . n 
G 1 28  THR 28  235 235 THR THR G . n 
G 1 29  ASN 29  236 236 ASN ASN G . n 
G 1 30  GLN 30  237 237 GLN GLN G . n 
G 1 31  LEU 31  238 238 LEU LEU G . n 
G 1 32  ARG 32  239 239 ARG ARG G . n 
G 1 33  LYS 33  240 240 LYS LYS G . n 
G 1 34  ALA 34  241 241 ALA ALA G . n 
G 1 35  VAL 35  242 242 VAL VAL G . n 
G 1 36  TYR 36  243 243 TYR TYR G . n 
G 1 37  MET 37  244 244 MET MET G . n 
G 1 38  MET 38  245 245 MET MET G . n 
G 1 39  PRO 39  246 246 PRO PRO G . n 
G 1 40  THR 40  247 247 THR THR G . n 
G 1 41  GLU 41  248 ?   ?   ?   G . n 
G 1 42  GLY 42  249 ?   ?   ?   G . n 
G 1 43  ASP 43  250 ?   ?   ?   G . n 
G 1 44  ASP 44  251 ?   ?   ?   G . n 
G 1 45  SER 45  252 ?   ?   ?   G . n 
G 1 46  SER 46  253 253 SER SER G . n 
G 1 47  LYS 47  254 254 LYS LYS G . n 
G 1 48  SER 48  255 255 SER SER G . n 
G 1 49  VAL 49  256 256 VAL VAL G . n 
G 1 50  PRO 50  257 257 PRO PRO G . n 
G 1 51  LEU 51  258 258 LEU LEU G . n 
G 1 52  ALA 52  259 259 ALA ALA G . n 
G 1 53  LEU 53  260 260 LEU LEU G . n 
G 1 54  GLN 54  261 261 GLN GLN G . n 
G 1 55  ARG 55  262 262 ARG ARG G . n 
G 1 56  VAL 56  263 263 VAL VAL G . n 
G 1 57  PHE 57  264 264 PHE PHE G . n 
G 1 58  TYR 58  265 265 TYR TYR G . n 
G 1 59  GLU 59  266 266 GLU GLU G . n 
G 1 60  LEU 60  267 267 LEU LEU G . n 
G 1 61  GLN 61  268 268 GLN GLN G . n 
G 1 62  HIS 62  269 269 HIS HIS G . n 
G 1 63  SER 63  270 ?   ?   ?   G . n 
G 1 64  ASP 64  271 271 ASP ASP G . n 
G 1 65  LYS 65  272 272 LYS LYS G . n 
G 1 66  PRO 66  273 ?   ?   ?   G . n 
G 1 67  VAL 67  274 274 VAL VAL G . n 
G 1 68  GLY 68  275 275 GLY GLY G . n 
G 1 69  THR 69  276 276 THR THR G . n 
G 1 70  LYS 70  277 277 LYS LYS G . n 
G 1 71  LYS 71  278 278 LYS LYS G . n 
G 1 72  LEU 72  279 279 LEU LEU G . n 
G 1 73  THR 73  280 280 THR THR G . n 
G 1 74  LYS 74  281 281 LYS LYS G . n 
G 1 75  SER 75  282 282 SER SER G . n 
G 1 76  PHE 76  283 283 PHE PHE G . n 
G 1 77  GLY 77  284 284 GLY GLY G . n 
G 1 78  TRP 78  285 285 TRP TRP G . n 
G 1 79  GLU 79  286 286 GLU GLU G . n 
G 1 80  THR 80  287 287 THR THR G . n 
G 1 81  LEU 81  288 288 LEU LEU G . n 
G 1 82  ASP 82  289 289 ASP ASP G . n 
G 1 83  SER 83  290 290 SER SER G . n 
G 1 84  PHE 84  291 291 PHE PHE G . n 
G 1 85  MET 85  292 292 MET MET G . n 
G 1 86  GLN 86  293 293 GLN GLN G . n 
G 1 87  HIS 87  294 294 HIS HIS G . n 
G 1 88  ASP 88  295 295 ASP ASP G . n 
G 1 89  VAL 89  296 296 VAL VAL G . n 
G 1 90  GLN 90  297 297 GLN GLN G . n 
G 1 91  GLU 91  298 298 GLU GLU G . n 
G 1 92  LEU 92  299 299 LEU LEU G . n 
G 1 93  CYS 93  300 300 CYS CYS G . n 
G 1 94  ARG 94  301 301 ARG ARG G . n 
G 1 95  VAL 95  302 302 VAL VAL G . n 
G 1 96  LEU 96  303 303 LEU LEU G . n 
G 1 97  LEU 97  304 304 LEU LEU G . n 
G 1 98  ASP 98  305 305 ASP ASP G . n 
G 1 99  ASN 99  306 306 ASN ASN G . n 
G 1 100 VAL 100 307 307 VAL VAL G . n 
G 1 101 GLU 101 308 308 GLU GLU G . n 
G 1 102 ASN 102 309 309 ASN ASN G . n 
G 1 103 LYS 103 310 310 LYS LYS G . n 
G 1 104 MET 104 311 311 MET MET G . n 
G 1 105 LYS 105 312 312 LYS LYS G . n 
G 1 106 GLY 106 313 313 GLY GLY G . n 
G 1 107 THR 107 314 314 THR THR G . n 
G 1 108 CYS 108 315 315 CYS CYS G . n 
G 1 109 VAL 109 316 316 VAL VAL G . n 
G 1 110 GLU 110 317 317 GLU GLU G . n 
G 1 111 GLY 111 318 318 GLY GLY G . n 
G 1 112 THR 112 319 319 THR THR G . n 
G 1 113 ILE 113 320 320 ILE ILE G . n 
G 1 114 PRO 114 321 321 PRO PRO G . n 
G 1 115 LYS 115 322 322 LYS LYS G . n 
G 1 116 LEU 116 323 323 LEU LEU G . n 
G 1 117 PHE 117 324 324 PHE PHE G . n 
G 1 118 ARG 118 325 325 ARG ARG G . n 
G 1 119 GLY 119 326 326 GLY GLY G . n 
G 1 120 LYS 120 327 327 LYS LYS G . n 
G 1 121 MET 121 328 328 MET MET G . n 
G 1 122 VAL 122 329 329 VAL VAL G . n 
G 1 123 SER 123 330 330 SER SER G . n 
G 1 124 TYR 124 331 331 TYR TYR G . n 
G 1 125 ILE 125 332 332 ILE ILE G . n 
G 1 126 GLN 126 333 333 GLN GLN G . n 
G 1 127 CYS 127 334 334 CYS CYS G . n 
G 1 128 LYS 128 335 335 LYS LYS G . n 
G 1 129 GLU 129 336 336 GLU GLU G . n 
G 1 130 VAL 130 337 337 VAL VAL G . n 
G 1 131 ASP 131 338 338 ASP ASP G . n 
G 1 132 TYR 132 339 339 TYR TYR G . n 
G 1 133 ARG 133 340 340 ARG ARG G . n 
G 1 134 SER 134 341 341 SER SER G . n 
G 1 135 ASP 135 342 342 ASP ASP G . n 
G 1 136 ARG 136 343 343 ARG ARG G . n 
G 1 137 ARG 137 344 344 ARG ARG G . n 
G 1 138 GLU 138 345 345 GLU GLU G . n 
G 1 139 ASP 139 346 346 ASP ASP G . n 
G 1 140 TYR 140 347 347 TYR TYR G . n 
G 1 141 TYR 141 348 348 TYR TYR G . n 
G 1 142 ASP 142 349 349 ASP ASP G . n 
G 1 143 ILE 143 350 350 ILE ILE G . n 
G 1 144 GLN 144 351 351 GLN GLN G . n 
G 1 145 LEU 145 352 352 LEU LEU G . n 
G 1 146 SER 146 353 353 SER SER G . n 
G 1 147 ILE 147 354 354 ILE ILE G . n 
G 1 148 LYS 148 355 355 LYS LYS G . n 
G 1 149 GLY 149 356 356 GLY GLY G . n 
G 1 150 LYS 150 357 357 LYS LYS G . n 
G 1 151 LYS 151 358 358 LYS LYS G . n 
G 1 152 ASN 152 359 359 ASN ASN G . n 
G 1 153 ILE 153 360 360 ILE ILE G . n 
G 1 154 PHE 154 361 361 PHE PHE G . n 
G 1 155 GLU 155 362 362 GLU GLU G . n 
G 1 156 SER 156 363 363 SER SER G . n 
G 1 157 PHE 157 364 364 PHE PHE G . n 
G 1 158 VAL 158 365 365 VAL VAL G . n 
G 1 159 ASP 159 366 366 ASP ASP G . n 
G 1 160 TYR 160 367 367 TYR TYR G . n 
G 1 161 VAL 161 368 368 VAL VAL G . n 
G 1 162 ALA 162 369 369 ALA ALA G . n 
G 1 163 VAL 163 370 370 VAL VAL G . n 
G 1 164 GLU 164 371 371 GLU GLU G . n 
G 1 165 GLN 165 372 372 GLN GLN G . n 
G 1 166 LEU 166 373 373 LEU LEU G . n 
G 1 167 ASP 167 374 374 ASP ASP G . n 
G 1 168 GLY 168 375 375 GLY GLY G . n 
G 1 169 ASP 169 376 376 ASP ASP G . n 
G 1 170 ASN 170 377 377 ASN ASN G . n 
G 1 171 LYS 171 378 378 LYS LYS G . n 
G 1 172 TYR 172 379 379 TYR TYR G . n 
G 1 173 ASP 173 380 380 ASP ASP G . n 
G 1 174 ALA 174 381 381 ALA ALA G . n 
G 1 175 GLY 175 382 382 GLY GLY G . n 
G 1 176 GLU 176 383 383 GLU GLU G . n 
G 1 177 HIS 177 384 384 HIS HIS G . n 
G 1 178 GLY 178 385 385 GLY GLY G . n 
G 1 179 LEU 179 386 386 LEU LEU G . n 
G 1 180 GLN 180 387 387 GLN GLN G . n 
G 1 181 GLU 181 388 388 GLU GLU G . n 
G 1 182 ALA 182 389 389 ALA ALA G . n 
G 1 183 GLU 183 390 390 GLU GLU G . n 
G 1 184 LYS 184 391 391 LYS LYS G . n 
G 1 185 GLY 185 392 392 GLY GLY G . n 
G 1 186 VAL 186 393 393 VAL VAL G . n 
G 1 187 LYS 187 394 394 LYS LYS G . n 
G 1 188 PHE 188 395 395 PHE PHE G . n 
G 1 189 LEU 189 396 396 LEU LEU G . n 
G 1 190 THR 190 397 397 THR THR G . n 
G 1 191 LEU 191 398 398 LEU LEU G . n 
G 1 192 PRO 192 399 399 PRO PRO G . n 
G 1 193 PRO 193 400 400 PRO PRO G . n 
G 1 194 VAL 194 401 401 VAL VAL G . n 
G 1 195 LEU 195 402 402 LEU LEU G . n 
G 1 196 HIS 196 403 403 HIS HIS G . n 
G 1 197 LEU 197 404 404 LEU LEU G . n 
G 1 198 GLN 198 405 405 GLN GLN G . n 
G 1 199 LEU 199 406 406 LEU LEU G . n 
G 1 200 MET 200 407 407 MET MET G . n 
G 1 201 ARG 201 408 408 ARG ARG G . n 
G 1 202 PHE 202 409 409 PHE PHE G . n 
G 1 203 MET 203 410 410 MET MET G . n 
G 1 204 TYR 204 411 411 TYR TYR G . n 
G 1 205 ASP 205 412 412 ASP ASP G . n 
G 1 206 PRO 206 413 413 PRO PRO G . n 
G 1 207 GLN 207 414 414 GLN GLN G . n 
G 1 208 THR 208 415 415 THR THR G . n 
G 1 209 ASP 209 416 ?   ?   ?   G . n 
G 1 210 GLN 210 417 ?   ?   ?   G . n 
G 1 211 ASN 211 418 ?   ?   ?   G . n 
G 1 212 ILE 212 419 419 ILE ILE G . n 
G 1 213 LYS 213 420 420 LYS LYS G . n 
G 1 214 ILE 214 421 421 ILE ILE G . n 
G 1 215 ASN 215 422 422 ASN ASN G . n 
G 1 216 ASP 216 423 423 ASP ASP G . n 
G 1 217 ARG 217 424 424 ARG ARG G . n 
G 1 218 PHE 218 425 425 PHE PHE G . n 
G 1 219 GLU 219 426 426 GLU GLU G . n 
G 1 220 PHE 220 427 427 PHE PHE G . n 
G 1 221 PRO 221 428 428 PRO PRO G . n 
G 1 222 GLU 222 429 429 GLU GLU G . n 
G 1 223 GLN 223 430 430 GLN GLN G . n 
G 1 224 LEU 224 431 431 LEU LEU G . n 
G 1 225 PRO 225 432 432 PRO PRO G . n 
G 1 226 LEU 226 433 433 LEU LEU G . n 
G 1 227 ASP 227 434 434 ASP ASP G . n 
G 1 228 GLU 228 435 435 GLU GLU G . n 
G 1 229 PHE 229 436 436 PHE PHE G . n 
G 1 230 LEU 230 437 437 LEU LEU G . n 
G 1 231 GLN 231 438 438 GLN GLN G . n 
G 1 232 LYS 232 439 439 LYS LYS G . n 
G 1 233 THR 233 440 440 THR THR G . n 
G 1 234 ASP 234 441 441 ASP ASP G . n 
G 1 235 PRO 235 442 442 PRO PRO G . n 
G 1 236 LYS 236 443 443 LYS LYS G . n 
G 1 237 ASP 237 444 444 ASP ASP G . n 
G 1 238 PRO 238 445 445 PRO PRO G . n 
G 1 239 ALA 239 446 446 ALA ALA G . n 
G 1 240 ASN 240 447 447 ASN ASN G . n 
G 1 241 TYR 241 448 448 TYR TYR G . n 
G 1 242 ILE 242 449 449 ILE ILE G . n 
G 1 243 LEU 243 450 450 LEU LEU G . n 
G 1 244 HIS 244 451 451 HIS HIS G . n 
G 1 245 ALA 245 452 452 ALA ALA G . n 
G 1 246 VAL 246 453 453 VAL VAL G . n 
G 1 247 LEU 247 454 454 LEU LEU G . n 
G 1 248 VAL 248 455 455 VAL VAL G . n 
G 1 249 HIS 249 456 456 HIS HIS G . n 
G 1 250 SER 250 457 457 SER SER G . n 
G 1 251 GLY 251 458 458 GLY GLY G . n 
G 1 252 ASP 252 459 459 ASP ASP G . n 
G 1 253 ASN 253 460 460 ASN ASN G . n 
G 1 254 HIS 254 461 461 HIS HIS G . n 
G 1 255 GLY 255 462 462 GLY GLY G . n 
G 1 256 GLY 256 463 463 GLY GLY G . n 
G 1 257 HIS 257 464 464 HIS HIS G . n 
G 1 258 TYR 258 465 465 TYR TYR G . n 
G 1 259 VAL 259 466 466 VAL VAL G . n 
G 1 260 VAL 260 467 467 VAL VAL G . n 
G 1 261 TYR 261 468 468 TYR TYR G . n 
G 1 262 LEU 262 469 469 LEU LEU G . n 
G 1 263 ASN 263 470 470 ASN ASN G . n 
G 1 264 PRO 264 471 471 PRO PRO G . n 
G 1 265 LYS 265 472 472 LYS LYS G . n 
G 1 266 GLY 266 473 473 GLY GLY G . n 
G 1 267 ASP 267 474 474 ASP ASP G . n 
G 1 268 GLY 268 475 475 GLY GLY G . n 
G 1 269 LYS 269 476 476 LYS LYS G . n 
G 1 270 TRP 270 477 477 TRP TRP G . n 
G 1 271 CYS 271 478 478 CYS CYS G . n 
G 1 272 LYS 272 479 479 LYS LYS G . n 
G 1 273 PHE 273 480 480 PHE PHE G . n 
G 1 274 ASP 274 481 481 ASP ASP G . n 
G 1 275 ASP 275 482 482 ASP ASP G . n 
G 1 276 ASP 276 483 483 ASP ASP G . n 
G 1 277 VAL 277 484 484 VAL VAL G . n 
G 1 278 VAL 278 485 485 VAL VAL G . n 
G 1 279 SER 279 486 486 SER SER G . n 
G 1 280 ARG 280 487 487 ARG ARG G . n 
G 1 281 CYS 281 488 488 CYS CYS G . n 
G 1 282 THR 282 489 489 THR THR G . n 
G 1 283 LYS 283 490 490 LYS LYS G . n 
G 1 284 GLU 284 491 491 GLU GLU G . n 
G 1 285 GLU 285 492 492 GLU GLU G . n 
G 1 286 ALA 286 493 493 ALA ALA G . n 
G 1 287 ILE 287 494 494 ILE ILE G . n 
G 1 288 GLU 288 495 495 GLU GLU G . n 
G 1 289 HIS 289 496 496 HIS HIS G . n 
G 1 290 ASN 290 497 497 ASN ASN G . n 
G 1 291 TYR 291 498 498 TYR TYR G . n 
G 1 292 GLY 292 499 ?   ?   ?   G . n 
G 1 293 GLY 293 500 ?   ?   ?   G . n 
G 1 294 HIS 294 501 ?   ?   ?   G . n 
G 1 295 ASP 295 502 ?   ?   ?   G . n 
G 1 296 ASP 296 503 ?   ?   ?   G . n 
G 1 297 ASP 297 504 ?   ?   ?   G . n 
G 1 298 LEU 298 505 ?   ?   ?   G . n 
G 1 299 SER 299 506 ?   ?   ?   G . n 
G 1 300 VAL 300 507 507 VAL VAL G . n 
G 1 301 ARG 301 508 508 ARG ARG G . n 
G 1 302 HIS 302 509 509 HIS HIS G . n 
G 1 303 CYS 303 510 510 CYS CYS G . n 
G 1 304 THR 304 511 511 THR THR G . n 
G 1 305 ASN 305 512 512 ASN ASN G . n 
G 1 306 ALA 306 513 513 ALA ALA G . n 
G 1 307 TYR 307 514 514 TYR TYR G . n 
G 1 308 MET 308 515 515 MET MET G . n 
G 1 309 LEU 309 516 516 LEU LEU G . n 
G 1 310 VAL 310 517 517 VAL VAL G . n 
G 1 311 TYR 311 518 518 TYR TYR G . n 
G 1 312 ILE 312 519 519 ILE ILE G . n 
G 1 313 ARG 313 520 520 ARG ARG G . n 
G 1 314 GLU 314 521 521 GLU GLU G . n 
G 1 315 SER 315 522 522 SER SER G . n 
G 1 316 LYS 316 523 523 LYS LYS G . n 
G 1 317 LEU 317 524 524 LEU LEU G . n 
G 1 318 SER 318 525 525 SER SER G . n 
G 1 319 GLU 319 526 526 GLU GLU G . n 
G 1 320 VAL 320 527 527 VAL VAL G . n 
G 1 321 LEU 321 528 528 LEU LEU G . n 
G 1 322 GLN 322 529 529 GLN GLN G . n 
G 1 323 ALA 323 530 530 ALA ALA G . n 
G 1 324 VAL 324 531 531 VAL VAL G . n 
G 1 325 THR 325 532 ?   ?   ?   G . n 
G 1 326 ASP 326 533 ?   ?   ?   G . n 
G 1 327 HIS 327 534 ?   ?   ?   G . n 
G 1 328 ASP 328 535 ?   ?   ?   G . n 
G 1 329 ILE 329 536 ?   ?   ?   G . n 
G 1 330 PRO 330 537 ?   ?   ?   G . n 
G 1 331 GLN 331 538 ?   ?   ?   G . n 
G 1 332 GLN 332 539 ?   ?   ?   G . n 
G 1 333 LEU 333 540 ?   ?   ?   G . n 
G 1 334 VAL 334 541 ?   ?   ?   G . n 
G 1 335 GLU 335 542 ?   ?   ?   G . n 
G 1 336 ARG 336 543 ?   ?   ?   G . n 
G 1 337 LEU 337 544 ?   ?   ?   G . n 
G 1 338 GLN 338 545 ?   ?   ?   G . n 
G 1 339 GLU 339 546 ?   ?   ?   G . n 
G 1 340 GLU 340 547 ?   ?   ?   G . n 
G 1 341 LYS 341 548 ?   ?   ?   G . n 
G 1 342 ARG 342 549 ?   ?   ?   G . n 
G 1 343 ILE 343 550 ?   ?   ?   G . n 
G 1 344 GLU 344 551 ?   ?   ?   G . n 
G 1 345 ALA 345 552 ?   ?   ?   G . n 
G 1 346 GLN 346 553 ?   ?   ?   G . n 
G 1 347 LYS 347 554 ?   ?   ?   G . n 
G 1 348 ARG 348 555 ?   ?   ?   G . n 
G 1 349 LYS 349 556 ?   ?   ?   G . n 
G 1 350 GLU 350 557 ?   ?   ?   G . n 
G 1 351 ARG 351 558 ?   ?   ?   G . n 
G 1 352 GLN 352 559 ?   ?   ?   G . n 
G 1 353 GLU 353 560 ?   ?   ?   G . n 
H 2 1   MET 1   1   1   MET MET H . n 
H 2 2   GLN 2   2   2   GLN GLN H . n 
H 2 3   ILE 3   3   3   ILE ILE H . n 
H 2 4   PHE 4   4   4   PHE PHE H . n 
H 2 5   VAL 5   5   5   VAL VAL H . n 
H 2 6   LYS 6   6   6   LYS LYS H . n 
H 2 7   THR 7   7   7   THR THR H . n 
H 2 8   LEU 8   8   8   LEU LEU H . n 
H 2 9   THR 9   9   9   THR THR H . n 
H 2 10  GLY 10  10  10  GLY GLY H . n 
H 2 11  LYS 11  11  11  LYS LYS H . n 
H 2 12  THR 12  12  12  THR THR H . n 
H 2 13  ILE 13  13  13  ILE ILE H . n 
H 2 14  THR 14  14  14  THR THR H . n 
H 2 15  LEU 15  15  15  LEU LEU H . n 
H 2 16  GLU 16  16  16  GLU GLU H . n 
H 2 17  VAL 17  17  17  VAL VAL H . n 
H 2 18  GLU 18  18  18  GLU GLU H . n 
H 2 19  PRO 19  19  19  PRO PRO H . n 
H 2 20  SER 20  20  20  SER SER H . n 
H 2 21  ASP 21  21  21  ASP ASP H . n 
H 2 22  THR 22  22  22  THR THR H . n 
H 2 23  ILE 23  23  23  ILE ILE H . n 
H 2 24  GLU 24  24  24  GLU GLU H . n 
H 2 25  ASN 25  25  25  ASN ASN H . n 
H 2 26  VAL 26  26  26  VAL VAL H . n 
H 2 27  LYS 27  27  27  LYS LYS H . n 
H 2 28  ALA 28  28  28  ALA ALA H . n 
H 2 29  LYS 29  29  29  LYS LYS H . n 
H 2 30  ILE 30  30  30  ILE ILE H . n 
H 2 31  GLN 31  31  31  GLN GLN H . n 
H 2 32  ASP 32  32  32  ASP ASP H . n 
H 2 33  LYS 33  33  33  LYS LYS H . n 
H 2 34  GLU 34  34  34  GLU GLU H . n 
H 2 35  GLY 35  35  35  GLY GLY H . n 
H 2 36  ILE 36  36  36  ILE ILE H . n 
H 2 37  PRO 37  37  37  PRO PRO H . n 
H 2 38  PRO 38  38  38  PRO PRO H . n 
H 2 39  ASP 39  39  39  ASP ASP H . n 
H 2 40  GLN 40  40  40  GLN GLN H . n 
H 2 41  GLN 41  41  41  GLN GLN H . n 
H 2 42  ARG 42  42  42  ARG ARG H . n 
H 2 43  LEU 43  43  43  LEU LEU H . n 
H 2 44  ILE 44  44  44  ILE ILE H . n 
H 2 45  PHE 45  45  45  PHE PHE H . n 
H 2 46  ALA 46  46  46  ALA ALA H . n 
H 2 47  GLY 47  47  47  GLY GLY H . n 
H 2 48  LYS 48  48  48  LYS LYS H . n 
H 2 49  GLN 49  49  49  GLN GLN H . n 
H 2 50  LEU 50  50  50  LEU LEU H . n 
H 2 51  GLU 51  51  51  GLU GLU H . n 
H 2 52  ASP 52  52  52  ASP ASP H . n 
H 2 53  GLY 53  53  53  GLY GLY H . n 
H 2 54  ARG 54  54  54  ARG ARG H . n 
H 2 55  THR 55  55  55  THR THR H . n 
H 2 56  LEU 56  56  56  LEU LEU H . n 
H 2 57  SER 57  57  57  SER SER H . n 
H 2 58  ASP 58  58  58  ASP ASP H . n 
H 2 59  TYR 59  59  59  TYR TYR H . n 
H 2 60  ASN 60  60  60  ASN ASN H . n 
H 2 61  ILE 61  61  61  ILE ILE H . n 
H 2 62  GLN 62  62  62  GLN GLN H . n 
H 2 63  LYS 63  63  63  LYS LYS H . n 
H 2 64  GLU 64  64  64  GLU GLU H . n 
H 2 65  SER 65  65  65  SER SER H . n 
H 2 66  THR 66  66  66  THR THR H . n 
H 2 67  LEU 67  67  67  LEU LEU H . n 
H 2 68  HIS 68  68  68  HIS HIS H . n 
H 2 69  LEU 69  69  69  LEU LEU H . n 
H 2 70  VAL 70  70  70  VAL VAL H . n 
H 2 71  LEU 71  71  71  LEU LEU H . n 
H 2 72  ARG 72  72  72  ARG ARG H . n 
H 2 73  LEU 73  73  73  LEU LEU H . n 
H 2 74  ARG 74  74  74  ARG ARG H . n 
H 2 75  GLY 75  75  75  GLY GLY H . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        XB7 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   XB7 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
I 3 XB7 1  601 601 XB7 LIG C . 
J 4 HOH 1  601 47  HOH HOH A . 
J 4 HOH 2  602 23  HOH HOH A . 
J 4 HOH 3  603 15  HOH HOH A . 
J 4 HOH 4  604 21  HOH HOH A . 
J 4 HOH 5  605 2   HOH HOH A . 
J 4 HOH 6  606 18  HOH HOH A . 
J 4 HOH 7  607 83  HOH HOH A . 
J 4 HOH 8  608 84  HOH HOH A . 
J 4 HOH 9  609 65  HOH HOH A . 
J 4 HOH 10 610 64  HOH HOH A . 
K 4 HOH 1  101 75  HOH HOH B . 
K 4 HOH 2  102 82  HOH HOH B . 
L 4 HOH 1  701 16  HOH HOH C . 
L 4 HOH 2  702 41  HOH HOH C . 
L 4 HOH 3  703 40  HOH HOH C . 
L 4 HOH 4  704 34  HOH HOH C . 
L 4 HOH 5  705 66  HOH HOH C . 
L 4 HOH 6  706 51  HOH HOH C . 
L 4 HOH 7  707 19  HOH HOH C . 
L 4 HOH 8  708 10  HOH HOH C . 
L 4 HOH 9  709 35  HOH HOH C . 
L 4 HOH 10 710 42  HOH HOH C . 
L 4 HOH 11 711 13  HOH HOH C . 
L 4 HOH 12 712 8   HOH HOH C . 
L 4 HOH 13 713 74  HOH HOH C . 
L 4 HOH 14 714 73  HOH HOH C . 
M 4 HOH 1  101 70  HOH HOH D . 
M 4 HOH 2  102 68  HOH HOH D . 
M 4 HOH 3  103 71  HOH HOH D . 
N 4 HOH 1  601 22  HOH HOH E . 
N 4 HOH 2  602 24  HOH HOH E . 
N 4 HOH 3  603 67  HOH HOH E . 
O 4 HOH 1  101 1   HOH HOH F . 
P 4 HOH 1  601 20  HOH HOH G . 
P 4 HOH 2  602 79  HOH HOH G . 
P 4 HOH 3  603 77  HOH HOH G . 
P 4 HOH 4  604 78  HOH HOH G . 
P 4 HOH 5  605 72  HOH HOH G . 
Q 4 HOH 1  101 57  HOH HOH H . 
Q 4 HOH 2  102 62  HOH HOH H . 
Q 4 HOH 3  103 76  HOH HOH H . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A VAL 214 ? CG1 ? A VAL 7   CG1 
2   1 Y 1 A VAL 214 ? CG2 ? A VAL 7   CG2 
3   1 Y 1 A LYS 217 ? CG  ? A LYS 10  CG  
4   1 Y 1 A LYS 217 ? CD  ? A LYS 10  CD  
5   1 Y 1 A LYS 217 ? CE  ? A LYS 10  CE  
6   1 Y 1 A LYS 217 ? NZ  ? A LYS 10  NZ  
7   1 Y 1 A GLN 219 ? CG  ? A GLN 12  CG  
8   1 Y 1 A GLN 219 ? CD  ? A GLN 12  CD  
9   1 Y 1 A GLN 219 ? OE1 ? A GLN 12  OE1 
10  1 Y 1 A GLN 219 ? NE2 ? A GLN 12  NE2 
11  1 Y 1 A LYS 240 ? CG  ? A LYS 33  CG  
12  1 Y 1 A LYS 240 ? CD  ? A LYS 33  CD  
13  1 Y 1 A LYS 240 ? CE  ? A LYS 33  CE  
14  1 Y 1 A LYS 240 ? NZ  ? A LYS 33  NZ  
15  1 Y 1 A THR 247 ? OG1 ? A THR 40  OG1 
16  1 Y 1 A THR 247 ? CG2 ? A THR 40  CG2 
17  1 Y 1 A GLU 248 ? CG  ? A GLU 41  CG  
18  1 Y 1 A GLU 248 ? CD  ? A GLU 41  CD  
19  1 Y 1 A GLU 248 ? OE1 ? A GLU 41  OE1 
20  1 Y 1 A GLU 248 ? OE2 ? A GLU 41  OE2 
21  1 Y 1 A LYS 254 ? CG  ? A LYS 47  CG  
22  1 Y 1 A LYS 254 ? CD  ? A LYS 47  CD  
23  1 Y 1 A LYS 254 ? CE  ? A LYS 47  CE  
24  1 Y 1 A LYS 254 ? NZ  ? A LYS 47  NZ  
25  1 Y 1 A LEU 258 ? CG  ? A LEU 51  CG  
26  1 Y 1 A LEU 258 ? CD1 ? A LEU 51  CD1 
27  1 Y 1 A LEU 258 ? CD2 ? A LEU 51  CD2 
28  1 Y 1 A ARG 262 ? CG  ? A ARG 55  CG  
29  1 Y 1 A ARG 262 ? CD  ? A ARG 55  CD  
30  1 Y 1 A ARG 262 ? NE  ? A ARG 55  NE  
31  1 Y 1 A ARG 262 ? CZ  ? A ARG 55  CZ  
32  1 Y 1 A ARG 262 ? NH1 ? A ARG 55  NH1 
33  1 Y 1 A ARG 262 ? NH2 ? A ARG 55  NH2 
34  1 Y 1 A LYS 272 ? CG  ? A LYS 65  CG  
35  1 Y 1 A LYS 272 ? CD  ? A LYS 65  CD  
36  1 Y 1 A LYS 272 ? CE  ? A LYS 65  CE  
37  1 Y 1 A LYS 272 ? NZ  ? A LYS 65  NZ  
38  1 Y 1 A LYS 278 ? CG  ? A LYS 71  CG  
39  1 Y 1 A LYS 278 ? CD  ? A LYS 71  CD  
40  1 Y 1 A LYS 278 ? CE  ? A LYS 71  CE  
41  1 Y 1 A LYS 278 ? NZ  ? A LYS 71  NZ  
42  1 Y 1 A LYS 281 ? CG  ? A LYS 74  CG  
43  1 Y 1 A LYS 281 ? CD  ? A LYS 74  CD  
44  1 Y 1 A LYS 281 ? CE  ? A LYS 74  CE  
45  1 Y 1 A LYS 281 ? NZ  ? A LYS 74  NZ  
46  1 Y 1 A GLU 286 ? CG  ? A GLU 79  CG  
47  1 Y 1 A GLU 286 ? CD  ? A GLU 79  CD  
48  1 Y 1 A GLU 286 ? OE1 ? A GLU 79  OE1 
49  1 Y 1 A GLU 286 ? OE2 ? A GLU 79  OE2 
50  1 Y 1 A LEU 288 ? CG  ? A LEU 81  CG  
51  1 Y 1 A LEU 288 ? CD1 ? A LEU 81  CD1 
52  1 Y 1 A LEU 288 ? CD2 ? A LEU 81  CD2 
53  1 Y 1 A PHE 291 ? CG  ? A PHE 84  CG  
54  1 Y 1 A PHE 291 ? CD1 ? A PHE 84  CD1 
55  1 Y 1 A PHE 291 ? CD2 ? A PHE 84  CD2 
56  1 Y 1 A PHE 291 ? CE1 ? A PHE 84  CE1 
57  1 Y 1 A PHE 291 ? CE2 ? A PHE 84  CE2 
58  1 Y 1 A PHE 291 ? CZ  ? A PHE 84  CZ  
59  1 Y 1 A LYS 310 ? CG  ? A LYS 103 CG  
60  1 Y 1 A LYS 310 ? CD  ? A LYS 103 CD  
61  1 Y 1 A LYS 310 ? CE  ? A LYS 103 CE  
62  1 Y 1 A LYS 310 ? NZ  ? A LYS 103 NZ  
63  1 Y 1 A LYS 312 ? CG  ? A LYS 105 CG  
64  1 Y 1 A LYS 312 ? CD  ? A LYS 105 CD  
65  1 Y 1 A LYS 312 ? CE  ? A LYS 105 CE  
66  1 Y 1 A LYS 312 ? NZ  ? A LYS 105 NZ  
67  1 Y 1 A LYS 322 ? CG  ? A LYS 115 CG  
68  1 Y 1 A LYS 322 ? CD  ? A LYS 115 CD  
69  1 Y 1 A LYS 322 ? CE  ? A LYS 115 CE  
70  1 Y 1 A LYS 322 ? NZ  ? A LYS 115 NZ  
71  1 Y 1 A ASP 338 ? CG  ? A ASP 131 CG  
72  1 Y 1 A ASP 338 ? OD1 ? A ASP 131 OD1 
73  1 Y 1 A ASP 338 ? OD2 ? A ASP 131 OD2 
74  1 Y 1 A ARG 340 ? CG  ? A ARG 133 CG  
75  1 Y 1 A ARG 340 ? CD  ? A ARG 133 CD  
76  1 Y 1 A ARG 340 ? NE  ? A ARG 133 NE  
77  1 Y 1 A ARG 340 ? CZ  ? A ARG 133 CZ  
78  1 Y 1 A ARG 340 ? NH1 ? A ARG 133 NH1 
79  1 Y 1 A ARG 340 ? NH2 ? A ARG 133 NH2 
80  1 Y 1 A LYS 355 ? CG  ? A LYS 148 CG  
81  1 Y 1 A LYS 355 ? CD  ? A LYS 148 CD  
82  1 Y 1 A LYS 355 ? CE  ? A LYS 148 CE  
83  1 Y 1 A LYS 355 ? NZ  ? A LYS 148 NZ  
84  1 Y 1 A LYS 358 ? CG  ? A LYS 151 CG  
85  1 Y 1 A LYS 358 ? CD  ? A LYS 151 CD  
86  1 Y 1 A LYS 358 ? CE  ? A LYS 151 CE  
87  1 Y 1 A LYS 358 ? NZ  ? A LYS 151 NZ  
88  1 Y 1 A PHE 361 ? CG  ? A PHE 154 CG  
89  1 Y 1 A PHE 361 ? CD1 ? A PHE 154 CD1 
90  1 Y 1 A PHE 361 ? CD2 ? A PHE 154 CD2 
91  1 Y 1 A PHE 361 ? CE1 ? A PHE 154 CE1 
92  1 Y 1 A PHE 361 ? CE2 ? A PHE 154 CE2 
93  1 Y 1 A PHE 361 ? CZ  ? A PHE 154 CZ  
94  1 Y 1 A GLU 383 ? CG  ? A GLU 176 CG  
95  1 Y 1 A GLU 383 ? CD  ? A GLU 176 CD  
96  1 Y 1 A GLU 383 ? OE1 ? A GLU 176 OE1 
97  1 Y 1 A GLU 383 ? OE2 ? A GLU 176 OE2 
98  1 Y 1 A MET 410 ? CG  ? A MET 203 CG  
99  1 Y 1 A MET 410 ? SD  ? A MET 203 SD  
100 1 Y 1 A MET 410 ? CE  ? A MET 203 CE  
101 1 Y 1 A GLU 426 ? CG  ? A GLU 219 CG  
102 1 Y 1 A GLU 426 ? CD  ? A GLU 219 CD  
103 1 Y 1 A GLU 426 ? OE1 ? A GLU 219 OE1 
104 1 Y 1 A GLU 426 ? OE2 ? A GLU 219 OE2 
105 1 Y 1 A GLU 429 ? CG  ? A GLU 222 CG  
106 1 Y 1 A GLU 429 ? CD  ? A GLU 222 CD  
107 1 Y 1 A GLU 429 ? OE1 ? A GLU 222 OE1 
108 1 Y 1 A GLU 429 ? OE2 ? A GLU 222 OE2 
109 1 Y 1 A GLU 435 ? CG  ? A GLU 228 CG  
110 1 Y 1 A GLU 435 ? CD  ? A GLU 228 CD  
111 1 Y 1 A GLU 435 ? OE1 ? A GLU 228 OE1 
112 1 Y 1 A GLU 435 ? OE2 ? A GLU 228 OE2 
113 1 Y 1 A LYS 439 ? CG  ? A LYS 232 CG  
114 1 Y 1 A LYS 439 ? CD  ? A LYS 232 CD  
115 1 Y 1 A LYS 439 ? CE  ? A LYS 232 CE  
116 1 Y 1 A LYS 439 ? NZ  ? A LYS 232 NZ  
117 1 Y 1 A LYS 443 ? CG  ? A LYS 236 CG  
118 1 Y 1 A LYS 443 ? CD  ? A LYS 236 CD  
119 1 Y 1 A LYS 443 ? CE  ? A LYS 236 CE  
120 1 Y 1 A LYS 443 ? NZ  ? A LYS 236 NZ  
121 1 Y 1 A LYS 476 ? CG  ? A LYS 269 CG  
122 1 Y 1 A LYS 476 ? CD  ? A LYS 269 CD  
123 1 Y 1 A LYS 476 ? CE  ? A LYS 269 CE  
124 1 Y 1 A LYS 476 ? NZ  ? A LYS 269 NZ  
125 1 Y 1 A ARG 487 ? CG  ? A ARG 280 CG  
126 1 Y 1 A ARG 487 ? CD  ? A ARG 280 CD  
127 1 Y 1 A ARG 487 ? NE  ? A ARG 280 NE  
128 1 Y 1 A ARG 487 ? CZ  ? A ARG 280 CZ  
129 1 Y 1 A ARG 487 ? NH1 ? A ARG 280 NH1 
130 1 Y 1 A ARG 487 ? NH2 ? A ARG 280 NH2 
131 1 Y 1 A GLU 521 ? CG  ? A GLU 314 CG  
132 1 Y 1 A GLU 521 ? CD  ? A GLU 314 CD  
133 1 Y 1 A GLU 521 ? OE1 ? A GLU 314 OE1 
134 1 Y 1 A GLU 521 ? OE2 ? A GLU 314 OE2 
135 1 Y 1 A GLN 529 ? CG  ? A GLN 322 CG  
136 1 Y 1 A GLN 529 ? CD  ? A GLN 322 CD  
137 1 Y 1 A GLN 529 ? OE1 ? A GLN 322 OE1 
138 1 Y 1 A GLN 529 ? NE2 ? A GLN 322 NE2 
139 1 Y 1 A GLN 538 ? CG  ? A GLN 331 CG  
140 1 Y 1 A GLN 538 ? CD  ? A GLN 331 CD  
141 1 Y 1 A GLN 538 ? OE1 ? A GLN 331 OE1 
142 1 Y 1 A GLN 538 ? NE2 ? A GLN 331 NE2 
143 1 Y 1 A GLN 539 ? CG  ? A GLN 332 CG  
144 1 Y 1 A GLN 539 ? CD  ? A GLN 332 CD  
145 1 Y 1 A GLN 539 ? OE1 ? A GLN 332 OE1 
146 1 Y 1 A GLN 539 ? NE2 ? A GLN 332 NE2 
147 1 Y 1 A GLU 542 ? CG  ? A GLU 335 CG  
148 1 Y 1 A GLU 542 ? CD  ? A GLU 335 CD  
149 1 Y 1 A GLU 542 ? OE1 ? A GLU 335 OE1 
150 1 Y 1 A GLU 542 ? OE2 ? A GLU 335 OE2 
151 1 Y 1 A ARG 543 ? CG  ? A ARG 336 CG  
152 1 Y 1 A ARG 543 ? CD  ? A ARG 336 CD  
153 1 Y 1 A ARG 543 ? NE  ? A ARG 336 NE  
154 1 Y 1 A ARG 543 ? CZ  ? A ARG 336 CZ  
155 1 Y 1 A ARG 543 ? NH1 ? A ARG 336 NH1 
156 1 Y 1 A ARG 543 ? NH2 ? A ARG 336 NH2 
157 1 Y 1 A LEU 544 ? CG  ? A LEU 337 CG  
158 1 Y 1 A LEU 544 ? CD1 ? A LEU 337 CD1 
159 1 Y 1 A LEU 544 ? CD2 ? A LEU 337 CD2 
160 1 Y 1 A GLN 545 ? CG  ? A GLN 338 CG  
161 1 Y 1 A GLN 545 ? CD  ? A GLN 338 CD  
162 1 Y 1 A GLN 545 ? OE1 ? A GLN 338 OE1 
163 1 Y 1 A GLN 545 ? NE2 ? A GLN 338 NE2 
164 1 Y 1 A GLU 546 ? CG  ? A GLU 339 CG  
165 1 Y 1 A GLU 546 ? CD  ? A GLU 339 CD  
166 1 Y 1 A GLU 546 ? OE1 ? A GLU 339 OE1 
167 1 Y 1 A GLU 546 ? OE2 ? A GLU 339 OE2 
168 1 Y 1 A GLU 547 ? CG  ? A GLU 340 CG  
169 1 Y 1 A GLU 547 ? CD  ? A GLU 340 CD  
170 1 Y 1 A GLU 547 ? OE1 ? A GLU 340 OE1 
171 1 Y 1 A GLU 547 ? OE2 ? A GLU 340 OE2 
172 1 Y 1 B LYS 11  ? CG  ? B LYS 11  CG  
173 1 Y 1 B LYS 11  ? CD  ? B LYS 11  CD  
174 1 Y 1 B LYS 11  ? CE  ? B LYS 11  CE  
175 1 Y 1 B LYS 11  ? NZ  ? B LYS 11  NZ  
176 1 Y 1 B LYS 48  ? CG  ? B LYS 48  CG  
177 1 Y 1 B LYS 48  ? CD  ? B LYS 48  CD  
178 1 Y 1 B LYS 48  ? CE  ? B LYS 48  CE  
179 1 Y 1 B LYS 48  ? NZ  ? B LYS 48  NZ  
180 1 Y 1 B ARG 54  ? CG  ? B ARG 54  CG  
181 1 Y 1 B ARG 54  ? CD  ? B ARG 54  CD  
182 1 Y 1 B ARG 54  ? NE  ? B ARG 54  NE  
183 1 Y 1 B ARG 54  ? CZ  ? B ARG 54  CZ  
184 1 Y 1 B ARG 54  ? NH1 ? B ARG 54  NH1 
185 1 Y 1 B ARG 54  ? NH2 ? B ARG 54  NH2 
186 1 Y 1 C LEU 216 ? CG  ? C LEU 9   CG  
187 1 Y 1 C LEU 216 ? CD1 ? C LEU 9   CD1 
188 1 Y 1 C LEU 216 ? CD2 ? C LEU 9   CD2 
189 1 Y 1 C LYS 217 ? CG  ? C LYS 10  CG  
190 1 Y 1 C LYS 217 ? CD  ? C LYS 10  CD  
191 1 Y 1 C LYS 217 ? CE  ? C LYS 10  CE  
192 1 Y 1 C LYS 217 ? NZ  ? C LYS 10  NZ  
193 1 Y 1 C LYS 240 ? CG  ? C LYS 33  CG  
194 1 Y 1 C LYS 240 ? CD  ? C LYS 33  CD  
195 1 Y 1 C LYS 240 ? CE  ? C LYS 33  CE  
196 1 Y 1 C LYS 240 ? NZ  ? C LYS 33  NZ  
197 1 Y 1 C MET 244 ? CG  ? C MET 37  CG  
198 1 Y 1 C MET 244 ? SD  ? C MET 37  SD  
199 1 Y 1 C MET 244 ? CE  ? C MET 37  CE  
200 1 Y 1 C GLU 248 ? CG  ? C GLU 41  CG  
201 1 Y 1 C GLU 248 ? CD  ? C GLU 41  CD  
202 1 Y 1 C GLU 248 ? OE1 ? C GLU 41  OE1 
203 1 Y 1 C GLU 248 ? OE2 ? C GLU 41  OE2 
204 1 Y 1 C LYS 254 ? CG  ? C LYS 47  CG  
205 1 Y 1 C LYS 254 ? CD  ? C LYS 47  CD  
206 1 Y 1 C LYS 254 ? CE  ? C LYS 47  CE  
207 1 Y 1 C LYS 254 ? NZ  ? C LYS 47  NZ  
208 1 Y 1 C LEU 258 ? CG  ? C LEU 51  CG  
209 1 Y 1 C LEU 258 ? CD1 ? C LEU 51  CD1 
210 1 Y 1 C LEU 258 ? CD2 ? C LEU 51  CD2 
211 1 Y 1 C ARG 262 ? CG  ? C ARG 55  CG  
212 1 Y 1 C ARG 262 ? CD  ? C ARG 55  CD  
213 1 Y 1 C ARG 262 ? NE  ? C ARG 55  NE  
214 1 Y 1 C ARG 262 ? CZ  ? C ARG 55  CZ  
215 1 Y 1 C ARG 262 ? NH1 ? C ARG 55  NH1 
216 1 Y 1 C ARG 262 ? NH2 ? C ARG 55  NH2 
217 1 Y 1 C GLU 266 ? CG  ? C GLU 59  CG  
218 1 Y 1 C GLU 266 ? CD  ? C GLU 59  CD  
219 1 Y 1 C GLU 266 ? OE1 ? C GLU 59  OE1 
220 1 Y 1 C GLU 266 ? OE2 ? C GLU 59  OE2 
221 1 Y 1 C LYS 272 ? CG  ? C LYS 65  CG  
222 1 Y 1 C LYS 272 ? CD  ? C LYS 65  CD  
223 1 Y 1 C LYS 272 ? CE  ? C LYS 65  CE  
224 1 Y 1 C LYS 272 ? NZ  ? C LYS 65  NZ  
225 1 Y 1 C LYS 277 ? CG  ? C LYS 70  CG  
226 1 Y 1 C LYS 277 ? CD  ? C LYS 70  CD  
227 1 Y 1 C LYS 277 ? CE  ? C LYS 70  CE  
228 1 Y 1 C LYS 277 ? NZ  ? C LYS 70  NZ  
229 1 Y 1 C LYS 278 ? CG  ? C LYS 71  CG  
230 1 Y 1 C LYS 278 ? CD  ? C LYS 71  CD  
231 1 Y 1 C LYS 278 ? CE  ? C LYS 71  CE  
232 1 Y 1 C LYS 278 ? NZ  ? C LYS 71  NZ  
233 1 Y 1 C LYS 281 ? CG  ? C LYS 74  CG  
234 1 Y 1 C LYS 281 ? CD  ? C LYS 74  CD  
235 1 Y 1 C LYS 281 ? CE  ? C LYS 74  CE  
236 1 Y 1 C LYS 281 ? NZ  ? C LYS 74  NZ  
237 1 Y 1 C GLU 286 ? CG  ? C GLU 79  CG  
238 1 Y 1 C GLU 286 ? CD  ? C GLU 79  CD  
239 1 Y 1 C GLU 286 ? OE1 ? C GLU 79  OE1 
240 1 Y 1 C GLU 286 ? OE2 ? C GLU 79  OE2 
241 1 Y 1 C LEU 288 ? CG  ? C LEU 81  CG  
242 1 Y 1 C LEU 288 ? CD1 ? C LEU 81  CD1 
243 1 Y 1 C LEU 288 ? CD2 ? C LEU 81  CD2 
244 1 Y 1 C GLN 293 ? CG  ? C GLN 86  CG  
245 1 Y 1 C GLN 293 ? CD  ? C GLN 86  CD  
246 1 Y 1 C GLN 293 ? OE1 ? C GLN 86  OE1 
247 1 Y 1 C GLN 293 ? NE2 ? C GLN 86  NE2 
248 1 Y 1 C LYS 312 ? CG  ? C LYS 105 CG  
249 1 Y 1 C LYS 312 ? CD  ? C LYS 105 CD  
250 1 Y 1 C LYS 312 ? CE  ? C LYS 105 CE  
251 1 Y 1 C LYS 312 ? NZ  ? C LYS 105 NZ  
252 1 Y 1 C LYS 322 ? CG  ? C LYS 115 CG  
253 1 Y 1 C LYS 322 ? CD  ? C LYS 115 CD  
254 1 Y 1 C LYS 322 ? CE  ? C LYS 115 CE  
255 1 Y 1 C LYS 322 ? NZ  ? C LYS 115 NZ  
256 1 Y 1 C LYS 358 ? CG  ? C LYS 151 CG  
257 1 Y 1 C LYS 358 ? CD  ? C LYS 151 CD  
258 1 Y 1 C LYS 358 ? CE  ? C LYS 151 CE  
259 1 Y 1 C LYS 358 ? NZ  ? C LYS 151 NZ  
260 1 Y 1 C GLU 383 ? CG  ? C GLU 176 CG  
261 1 Y 1 C GLU 383 ? CD  ? C GLU 176 CD  
262 1 Y 1 C GLU 383 ? OE1 ? C GLU 176 OE1 
263 1 Y 1 C GLU 383 ? OE2 ? C GLU 176 OE2 
264 1 Y 1 C ARG 424 ? CG  ? C ARG 217 CG  
265 1 Y 1 C ARG 424 ? CD  ? C ARG 217 CD  
266 1 Y 1 C ARG 424 ? NE  ? C ARG 217 NE  
267 1 Y 1 C ARG 424 ? CZ  ? C ARG 217 CZ  
268 1 Y 1 C ARG 424 ? NH1 ? C ARG 217 NH1 
269 1 Y 1 C ARG 424 ? NH2 ? C ARG 217 NH2 
270 1 Y 1 C LYS 443 ? CG  ? C LYS 236 CG  
271 1 Y 1 C LYS 443 ? CD  ? C LYS 236 CD  
272 1 Y 1 C LYS 443 ? CE  ? C LYS 236 CE  
273 1 Y 1 C LYS 443 ? NZ  ? C LYS 236 NZ  
274 1 Y 1 C ASN 460 ? CG  ? C ASN 253 CG  
275 1 Y 1 C ASN 460 ? OD1 ? C ASN 253 OD1 
276 1 Y 1 C ASN 460 ? ND2 ? C ASN 253 ND2 
277 1 Y 1 C HIS 461 ? CG  ? C HIS 254 CG  
278 1 Y 1 C HIS 461 ? ND1 ? C HIS 254 ND1 
279 1 Y 1 C HIS 461 ? CD2 ? C HIS 254 CD2 
280 1 Y 1 C HIS 461 ? CE1 ? C HIS 254 CE1 
281 1 Y 1 C HIS 461 ? NE2 ? C HIS 254 NE2 
282 1 Y 1 C LYS 472 ? CG  ? C LYS 265 CG  
283 1 Y 1 C LYS 472 ? CD  ? C LYS 265 CD  
284 1 Y 1 C LYS 472 ? CE  ? C LYS 265 CE  
285 1 Y 1 C LYS 472 ? NZ  ? C LYS 265 NZ  
286 1 Y 1 C LYS 476 ? CG  ? C LYS 269 CG  
287 1 Y 1 C LYS 476 ? CD  ? C LYS 269 CD  
288 1 Y 1 C LYS 476 ? CE  ? C LYS 269 CE  
289 1 Y 1 C LYS 476 ? NZ  ? C LYS 269 NZ  
290 1 Y 1 C ARG 487 ? CG  ? C ARG 280 CG  
291 1 Y 1 C ARG 487 ? CD  ? C ARG 280 CD  
292 1 Y 1 C ARG 487 ? NE  ? C ARG 280 NE  
293 1 Y 1 C ARG 487 ? CZ  ? C ARG 280 CZ  
294 1 Y 1 C ARG 487 ? NH1 ? C ARG 280 NH1 
295 1 Y 1 C ARG 487 ? NH2 ? C ARG 280 NH2 
296 1 Y 1 C GLU 491 ? CG  ? C GLU 284 CG  
297 1 Y 1 C GLU 491 ? CD  ? C GLU 284 CD  
298 1 Y 1 C GLU 491 ? OE1 ? C GLU 284 OE1 
299 1 Y 1 C GLU 491 ? OE2 ? C GLU 284 OE2 
300 1 Y 1 C GLN 529 ? CG  ? C GLN 322 CG  
301 1 Y 1 C GLN 529 ? CD  ? C GLN 322 CD  
302 1 Y 1 C GLN 529 ? OE1 ? C GLN 322 OE1 
303 1 Y 1 C GLN 529 ? NE2 ? C GLN 322 NE2 
304 1 Y 1 D LYS 6   ? CE  ? D LYS 6   CE  
305 1 Y 1 D LYS 6   ? NZ  ? D LYS 6   NZ  
306 1 Y 1 D LYS 11  ? CG  ? D LYS 11  CG  
307 1 Y 1 D LYS 11  ? CD  ? D LYS 11  CD  
308 1 Y 1 D LYS 11  ? CE  ? D LYS 11  CE  
309 1 Y 1 D LYS 11  ? NZ  ? D LYS 11  NZ  
310 1 Y 1 D LYS 29  ? CG  ? D LYS 29  CG  
311 1 Y 1 D LYS 29  ? CD  ? D LYS 29  CD  
312 1 Y 1 D LYS 29  ? CE  ? D LYS 29  CE  
313 1 Y 1 D LYS 29  ? NZ  ? D LYS 29  NZ  
314 1 Y 1 D GLN 31  ? CG  ? D GLN 31  CG  
315 1 Y 1 D GLN 31  ? CD  ? D GLN 31  CD  
316 1 Y 1 D GLN 31  ? OE1 ? D GLN 31  OE1 
317 1 Y 1 D GLN 31  ? NE2 ? D GLN 31  NE2 
318 1 Y 1 D LYS 48  ? CG  ? D LYS 48  CG  
319 1 Y 1 D LYS 48  ? CD  ? D LYS 48  CD  
320 1 Y 1 D LYS 48  ? CE  ? D LYS 48  CE  
321 1 Y 1 D LYS 48  ? NZ  ? D LYS 48  NZ  
322 1 Y 1 D ARG 54  ? CG  ? D ARG 54  CG  
323 1 Y 1 D ARG 54  ? CD  ? D ARG 54  CD  
324 1 Y 1 D ARG 54  ? NE  ? D ARG 54  NE  
325 1 Y 1 D ARG 54  ? CZ  ? D ARG 54  CZ  
326 1 Y 1 D ARG 54  ? NH1 ? D ARG 54  NH1 
327 1 Y 1 D ARG 54  ? NH2 ? D ARG 54  NH2 
328 1 Y 1 D LYS 63  ? NZ  ? D LYS 63  NZ  
329 1 Y 1 E LYS 240 ? CG  ? E LYS 33  CG  
330 1 Y 1 E LYS 240 ? CD  ? E LYS 33  CD  
331 1 Y 1 E LYS 240 ? CE  ? E LYS 33  CE  
332 1 Y 1 E LYS 240 ? NZ  ? E LYS 33  NZ  
333 1 Y 1 E GLU 248 ? CG  ? E GLU 41  CG  
334 1 Y 1 E GLU 248 ? CD  ? E GLU 41  CD  
335 1 Y 1 E GLU 248 ? OE1 ? E GLU 41  OE1 
336 1 Y 1 E GLU 248 ? OE2 ? E GLU 41  OE2 
337 1 Y 1 E LYS 254 ? CG  ? E LYS 47  CG  
338 1 Y 1 E LYS 254 ? CD  ? E LYS 47  CD  
339 1 Y 1 E LYS 254 ? CE  ? E LYS 47  CE  
340 1 Y 1 E LYS 254 ? NZ  ? E LYS 47  NZ  
341 1 Y 1 E LEU 258 ? CG  ? E LEU 51  CG  
342 1 Y 1 E LEU 258 ? CD1 ? E LEU 51  CD1 
343 1 Y 1 E LEU 258 ? CD2 ? E LEU 51  CD2 
344 1 Y 1 E ARG 262 ? CZ  ? E ARG 55  CZ  
345 1 Y 1 E ARG 262 ? NH1 ? E ARG 55  NH1 
346 1 Y 1 E ARG 262 ? NH2 ? E ARG 55  NH2 
347 1 Y 1 E HIS 269 ? CG  ? E HIS 62  CG  
348 1 Y 1 E HIS 269 ? ND1 ? E HIS 62  ND1 
349 1 Y 1 E HIS 269 ? CD2 ? E HIS 62  CD2 
350 1 Y 1 E HIS 269 ? CE1 ? E HIS 62  CE1 
351 1 Y 1 E HIS 269 ? NE2 ? E HIS 62  NE2 
352 1 Y 1 E LYS 272 ? CG  ? E LYS 65  CG  
353 1 Y 1 E LYS 272 ? CD  ? E LYS 65  CD  
354 1 Y 1 E LYS 272 ? CE  ? E LYS 65  CE  
355 1 Y 1 E LYS 272 ? NZ  ? E LYS 65  NZ  
356 1 Y 1 E LYS 277 ? CG  ? E LYS 70  CG  
357 1 Y 1 E LYS 277 ? CD  ? E LYS 70  CD  
358 1 Y 1 E LYS 277 ? CE  ? E LYS 70  CE  
359 1 Y 1 E LYS 277 ? NZ  ? E LYS 70  NZ  
360 1 Y 1 E LYS 278 ? CG  ? E LYS 71  CG  
361 1 Y 1 E LYS 278 ? CD  ? E LYS 71  CD  
362 1 Y 1 E LYS 278 ? CE  ? E LYS 71  CE  
363 1 Y 1 E LYS 278 ? NZ  ? E LYS 71  NZ  
364 1 Y 1 E LYS 281 ? CG  ? E LYS 74  CG  
365 1 Y 1 E LYS 281 ? CD  ? E LYS 74  CD  
366 1 Y 1 E LYS 281 ? CE  ? E LYS 74  CE  
367 1 Y 1 E LYS 281 ? NZ  ? E LYS 74  NZ  
368 1 Y 1 E GLU 286 ? CD  ? E GLU 79  CD  
369 1 Y 1 E GLU 286 ? OE1 ? E GLU 79  OE1 
370 1 Y 1 E GLU 286 ? OE2 ? E GLU 79  OE2 
371 1 Y 1 E LYS 310 ? CG  ? E LYS 103 CG  
372 1 Y 1 E LYS 310 ? CD  ? E LYS 103 CD  
373 1 Y 1 E LYS 310 ? CE  ? E LYS 103 CE  
374 1 Y 1 E LYS 310 ? NZ  ? E LYS 103 NZ  
375 1 Y 1 E LYS 312 ? CG  ? E LYS 105 CG  
376 1 Y 1 E LYS 312 ? CD  ? E LYS 105 CD  
377 1 Y 1 E LYS 312 ? CE  ? E LYS 105 CE  
378 1 Y 1 E LYS 312 ? NZ  ? E LYS 105 NZ  
379 1 Y 1 E LYS 322 ? CG  ? E LYS 115 CG  
380 1 Y 1 E LYS 322 ? CD  ? E LYS 115 CD  
381 1 Y 1 E LYS 322 ? CE  ? E LYS 115 CE  
382 1 Y 1 E LYS 322 ? NZ  ? E LYS 115 NZ  
383 1 Y 1 E LYS 355 ? CG  ? E LYS 148 CG  
384 1 Y 1 E LYS 355 ? CD  ? E LYS 148 CD  
385 1 Y 1 E LYS 355 ? CE  ? E LYS 148 CE  
386 1 Y 1 E LYS 355 ? NZ  ? E LYS 148 NZ  
387 1 Y 1 E LYS 357 ? CG  ? E LYS 150 CG  
388 1 Y 1 E LYS 357 ? CD  ? E LYS 150 CD  
389 1 Y 1 E LYS 357 ? CE  ? E LYS 150 CE  
390 1 Y 1 E LYS 357 ? NZ  ? E LYS 150 NZ  
391 1 Y 1 E LYS 358 ? CG  ? E LYS 151 CG  
392 1 Y 1 E LYS 358 ? CD  ? E LYS 151 CD  
393 1 Y 1 E LYS 358 ? CE  ? E LYS 151 CE  
394 1 Y 1 E LYS 358 ? NZ  ? E LYS 151 NZ  
395 1 Y 1 E PHE 361 ? CG  ? E PHE 154 CG  
396 1 Y 1 E PHE 361 ? CD1 ? E PHE 154 CD1 
397 1 Y 1 E PHE 361 ? CD2 ? E PHE 154 CD2 
398 1 Y 1 E PHE 361 ? CE1 ? E PHE 154 CE1 
399 1 Y 1 E PHE 361 ? CE2 ? E PHE 154 CE2 
400 1 Y 1 E PHE 361 ? CZ  ? E PHE 154 CZ  
401 1 Y 1 E GLU 383 ? CG  ? E GLU 176 CG  
402 1 Y 1 E GLU 383 ? CD  ? E GLU 176 CD  
403 1 Y 1 E GLU 383 ? OE1 ? E GLU 176 OE1 
404 1 Y 1 E GLU 383 ? OE2 ? E GLU 176 OE2 
405 1 Y 1 E TYR 411 ? CG  ? E TYR 204 CG  
406 1 Y 1 E TYR 411 ? CD1 ? E TYR 204 CD1 
407 1 Y 1 E TYR 411 ? CD2 ? E TYR 204 CD2 
408 1 Y 1 E TYR 411 ? CE1 ? E TYR 204 CE1 
409 1 Y 1 E TYR 411 ? CE2 ? E TYR 204 CE2 
410 1 Y 1 E TYR 411 ? CZ  ? E TYR 204 CZ  
411 1 Y 1 E TYR 411 ? OH  ? E TYR 204 OH  
412 1 Y 1 E GLN 417 ? CG  ? E GLN 210 CG  
413 1 Y 1 E GLN 417 ? CD  ? E GLN 210 CD  
414 1 Y 1 E GLN 417 ? OE1 ? E GLN 210 OE1 
415 1 Y 1 E GLN 417 ? NE2 ? E GLN 210 NE2 
416 1 Y 1 E ARG 424 ? CG  ? E ARG 217 CG  
417 1 Y 1 E ARG 424 ? CD  ? E ARG 217 CD  
418 1 Y 1 E ARG 424 ? NE  ? E ARG 217 NE  
419 1 Y 1 E ARG 424 ? CZ  ? E ARG 217 CZ  
420 1 Y 1 E ARG 424 ? NH1 ? E ARG 217 NH1 
421 1 Y 1 E ARG 424 ? NH2 ? E ARG 217 NH2 
422 1 Y 1 E GLU 426 ? CG  ? E GLU 219 CG  
423 1 Y 1 E GLU 426 ? CD  ? E GLU 219 CD  
424 1 Y 1 E GLU 426 ? OE1 ? E GLU 219 OE1 
425 1 Y 1 E GLU 426 ? OE2 ? E GLU 219 OE2 
426 1 Y 1 E LYS 443 ? CG  ? E LYS 236 CG  
427 1 Y 1 E LYS 443 ? CD  ? E LYS 236 CD  
428 1 Y 1 E LYS 443 ? CE  ? E LYS 236 CE  
429 1 Y 1 E LYS 443 ? NZ  ? E LYS 236 NZ  
430 1 Y 1 E ASN 447 ? CG  ? E ASN 240 CG  
431 1 Y 1 E ASN 447 ? OD1 ? E ASN 240 OD1 
432 1 Y 1 E ASN 447 ? ND2 ? E ASN 240 ND2 
433 1 Y 1 E LYS 472 ? CG  ? E LYS 265 CG  
434 1 Y 1 E LYS 472 ? CD  ? E LYS 265 CD  
435 1 Y 1 E LYS 472 ? CE  ? E LYS 265 CE  
436 1 Y 1 E LYS 472 ? NZ  ? E LYS 265 NZ  
437 1 Y 1 E LYS 476 ? CG  ? E LYS 269 CG  
438 1 Y 1 E LYS 476 ? CD  ? E LYS 269 CD  
439 1 Y 1 E LYS 476 ? CE  ? E LYS 269 CE  
440 1 Y 1 E LYS 476 ? NZ  ? E LYS 269 NZ  
441 1 Y 1 E LYS 479 ? CG  ? E LYS 272 CG  
442 1 Y 1 E LYS 479 ? CD  ? E LYS 272 CD  
443 1 Y 1 E LYS 479 ? CE  ? E LYS 272 CE  
444 1 Y 1 E LYS 479 ? NZ  ? E LYS 272 NZ  
445 1 Y 1 E ARG 487 ? CG  ? E ARG 280 CG  
446 1 Y 1 E ARG 487 ? CD  ? E ARG 280 CD  
447 1 Y 1 E ARG 487 ? NE  ? E ARG 280 NE  
448 1 Y 1 E ARG 487 ? CZ  ? E ARG 280 CZ  
449 1 Y 1 E ARG 487 ? NH1 ? E ARG 280 NH1 
450 1 Y 1 E ARG 487 ? NH2 ? E ARG 280 NH2 
451 1 Y 1 E CYS 488 ? SG  ? E CYS 281 SG  
452 1 Y 1 E LYS 490 ? CG  ? E LYS 283 CG  
453 1 Y 1 E LYS 490 ? CD  ? E LYS 283 CD  
454 1 Y 1 E LYS 490 ? CE  ? E LYS 283 CE  
455 1 Y 1 E LYS 490 ? NZ  ? E LYS 283 NZ  
456 1 Y 1 E GLU 491 ? CG  ? E GLU 284 CG  
457 1 Y 1 E GLU 491 ? CD  ? E GLU 284 CD  
458 1 Y 1 E GLU 491 ? OE1 ? E GLU 284 OE1 
459 1 Y 1 E GLU 491 ? OE2 ? E GLU 284 OE2 
460 1 Y 1 E GLU 492 ? CG  ? E GLU 285 CG  
461 1 Y 1 E GLU 492 ? CD  ? E GLU 285 CD  
462 1 Y 1 E GLU 492 ? OE1 ? E GLU 285 OE1 
463 1 Y 1 E GLU 492 ? OE2 ? E GLU 285 OE2 
464 1 Y 1 E HIS 496 ? CG  ? E HIS 289 CG  
465 1 Y 1 E HIS 496 ? ND1 ? E HIS 289 ND1 
466 1 Y 1 E HIS 496 ? CD2 ? E HIS 289 CD2 
467 1 Y 1 E HIS 496 ? CE1 ? E HIS 289 CE1 
468 1 Y 1 E HIS 496 ? NE2 ? E HIS 289 NE2 
469 1 Y 1 E ARG 508 ? CG  ? E ARG 301 CG  
470 1 Y 1 E ARG 508 ? CD  ? E ARG 301 CD  
471 1 Y 1 E ARG 508 ? NE  ? E ARG 301 NE  
472 1 Y 1 E ARG 508 ? CZ  ? E ARG 301 CZ  
473 1 Y 1 E ARG 508 ? NH1 ? E ARG 301 NH1 
474 1 Y 1 E ARG 508 ? NH2 ? E ARG 301 NH2 
475 1 Y 1 E HIS 509 ? CG  ? E HIS 302 CG  
476 1 Y 1 E HIS 509 ? ND1 ? E HIS 302 ND1 
477 1 Y 1 E HIS 509 ? CD2 ? E HIS 302 CD2 
478 1 Y 1 E HIS 509 ? CE1 ? E HIS 302 CE1 
479 1 Y 1 E HIS 509 ? NE2 ? E HIS 302 NE2 
480 1 Y 1 E GLU 521 ? CG  ? E GLU 314 CG  
481 1 Y 1 E GLU 521 ? CD  ? E GLU 314 CD  
482 1 Y 1 E GLU 521 ? OE1 ? E GLU 314 OE1 
483 1 Y 1 E GLU 521 ? OE2 ? E GLU 314 OE2 
484 1 Y 1 E LYS 523 ? CG  ? E LYS 316 CG  
485 1 Y 1 E LYS 523 ? CD  ? E LYS 316 CD  
486 1 Y 1 E LYS 523 ? CE  ? E LYS 316 CE  
487 1 Y 1 E LYS 523 ? NZ  ? E LYS 316 NZ  
488 1 Y 1 E GLN 529 ? CG  ? E GLN 322 CG  
489 1 Y 1 E GLN 529 ? CD  ? E GLN 322 CD  
490 1 Y 1 E GLN 529 ? OE1 ? E GLN 322 OE1 
491 1 Y 1 E GLN 529 ? NE2 ? E GLN 322 NE2 
492 1 Y 1 E HIS 534 ? CG  ? E HIS 327 CG  
493 1 Y 1 E HIS 534 ? ND1 ? E HIS 327 ND1 
494 1 Y 1 E HIS 534 ? CD2 ? E HIS 327 CD2 
495 1 Y 1 E HIS 534 ? CE1 ? E HIS 327 CE1 
496 1 Y 1 E HIS 534 ? NE2 ? E HIS 327 NE2 
497 1 Y 1 E GLN 538 ? CG  ? E GLN 331 CG  
498 1 Y 1 E GLN 538 ? CD  ? E GLN 331 CD  
499 1 Y 1 E GLN 538 ? OE1 ? E GLN 331 OE1 
500 1 Y 1 E GLN 538 ? NE2 ? E GLN 331 NE2 
501 1 Y 1 E GLN 539 ? CG  ? E GLN 332 CG  
502 1 Y 1 E GLN 539 ? CD  ? E GLN 332 CD  
503 1 Y 1 E GLN 539 ? OE1 ? E GLN 332 OE1 
504 1 Y 1 E GLN 539 ? NE2 ? E GLN 332 NE2 
505 1 Y 1 E GLU 542 ? CG  ? E GLU 335 CG  
506 1 Y 1 E GLU 542 ? CD  ? E GLU 335 CD  
507 1 Y 1 E GLU 542 ? OE1 ? E GLU 335 OE1 
508 1 Y 1 E GLU 542 ? OE2 ? E GLU 335 OE2 
509 1 Y 1 E ARG 543 ? CG  ? E ARG 336 CG  
510 1 Y 1 E ARG 543 ? CD  ? E ARG 336 CD  
511 1 Y 1 E ARG 543 ? NE  ? E ARG 336 NE  
512 1 Y 1 E ARG 543 ? CZ  ? E ARG 336 CZ  
513 1 Y 1 E ARG 543 ? NH1 ? E ARG 336 NH1 
514 1 Y 1 E ARG 543 ? NH2 ? E ARG 336 NH2 
515 1 Y 1 E GLN 545 ? CG  ? E GLN 338 CG  
516 1 Y 1 E GLN 545 ? CD  ? E GLN 338 CD  
517 1 Y 1 E GLN 545 ? OE1 ? E GLN 338 OE1 
518 1 Y 1 E GLN 545 ? NE2 ? E GLN 338 NE2 
519 1 Y 1 E GLU 546 ? CG  ? E GLU 339 CG  
520 1 Y 1 E GLU 546 ? CD  ? E GLU 339 CD  
521 1 Y 1 E GLU 546 ? OE1 ? E GLU 339 OE1 
522 1 Y 1 E GLU 546 ? OE2 ? E GLU 339 OE2 
523 1 Y 1 E GLU 547 ? CG  ? E GLU 340 CG  
524 1 Y 1 E GLU 547 ? CD  ? E GLU 340 CD  
525 1 Y 1 E GLU 547 ? OE1 ? E GLU 340 OE1 
526 1 Y 1 E GLU 547 ? OE2 ? E GLU 340 OE2 
527 1 Y 1 F LYS 11  ? CG  ? F LYS 11  CG  
528 1 Y 1 F LYS 11  ? CD  ? F LYS 11  CD  
529 1 Y 1 F LYS 11  ? CE  ? F LYS 11  CE  
530 1 Y 1 F LYS 11  ? NZ  ? F LYS 11  NZ  
531 1 Y 1 F LYS 48  ? CG  ? F LYS 48  CG  
532 1 Y 1 F LYS 48  ? CD  ? F LYS 48  CD  
533 1 Y 1 F LYS 48  ? CE  ? F LYS 48  CE  
534 1 Y 1 F LYS 48  ? NZ  ? F LYS 48  NZ  
535 1 Y 1 F ARG 54  ? CG  ? F ARG 54  CG  
536 1 Y 1 F ARG 54  ? CD  ? F ARG 54  CD  
537 1 Y 1 F ARG 54  ? NE  ? F ARG 54  NE  
538 1 Y 1 F ARG 54  ? CZ  ? F ARG 54  CZ  
539 1 Y 1 F ARG 54  ? NH1 ? F ARG 54  NH1 
540 1 Y 1 F ARG 54  ? NH2 ? F ARG 54  NH2 
541 1 Y 1 G LEU 216 ? CG  ? G LEU 9   CG  
542 1 Y 1 G LEU 216 ? CD1 ? G LEU 9   CD1 
543 1 Y 1 G LEU 216 ? CD2 ? G LEU 9   CD2 
544 1 Y 1 G LYS 240 ? CG  ? G LYS 33  CG  
545 1 Y 1 G LYS 240 ? CD  ? G LYS 33  CD  
546 1 Y 1 G LYS 240 ? CE  ? G LYS 33  CE  
547 1 Y 1 G LYS 240 ? NZ  ? G LYS 33  NZ  
548 1 Y 1 G MET 244 ? CG  ? G MET 37  CG  
549 1 Y 1 G MET 244 ? SD  ? G MET 37  SD  
550 1 Y 1 G MET 244 ? CE  ? G MET 37  CE  
551 1 Y 1 G LYS 254 ? CG  ? G LYS 47  CG  
552 1 Y 1 G LYS 254 ? CD  ? G LYS 47  CD  
553 1 Y 1 G LYS 254 ? CE  ? G LYS 47  CE  
554 1 Y 1 G LYS 254 ? NZ  ? G LYS 47  NZ  
555 1 Y 1 G SER 255 ? OG  ? G SER 48  OG  
556 1 Y 1 G LEU 258 ? CG  ? G LEU 51  CG  
557 1 Y 1 G LEU 258 ? CD1 ? G LEU 51  CD1 
558 1 Y 1 G LEU 258 ? CD2 ? G LEU 51  CD2 
559 1 Y 1 G GLN 261 ? CG  ? G GLN 54  CG  
560 1 Y 1 G GLN 261 ? CD  ? G GLN 54  CD  
561 1 Y 1 G GLN 261 ? OE1 ? G GLN 54  OE1 
562 1 Y 1 G GLN 261 ? NE2 ? G GLN 54  NE2 
563 1 Y 1 G ARG 262 ? CG  ? G ARG 55  CG  
564 1 Y 1 G ARG 262 ? CD  ? G ARG 55  CD  
565 1 Y 1 G ARG 262 ? NE  ? G ARG 55  NE  
566 1 Y 1 G ARG 262 ? CZ  ? G ARG 55  CZ  
567 1 Y 1 G ARG 262 ? NH1 ? G ARG 55  NH1 
568 1 Y 1 G ARG 262 ? NH2 ? G ARG 55  NH2 
569 1 Y 1 G GLU 266 ? CG  ? G GLU 59  CG  
570 1 Y 1 G GLU 266 ? CD  ? G GLU 59  CD  
571 1 Y 1 G GLU 266 ? OE1 ? G GLU 59  OE1 
572 1 Y 1 G GLU 266 ? OE2 ? G GLU 59  OE2 
573 1 Y 1 G LEU 267 ? CG  ? G LEU 60  CG  
574 1 Y 1 G LEU 267 ? CD1 ? G LEU 60  CD1 
575 1 Y 1 G LEU 267 ? CD2 ? G LEU 60  CD2 
576 1 Y 1 G GLN 268 ? CG  ? G GLN 61  CG  
577 1 Y 1 G GLN 268 ? CD  ? G GLN 61  CD  
578 1 Y 1 G GLN 268 ? OE1 ? G GLN 61  OE1 
579 1 Y 1 G GLN 268 ? NE2 ? G GLN 61  NE2 
580 1 Y 1 G HIS 269 ? CG  ? G HIS 62  CG  
581 1 Y 1 G HIS 269 ? ND1 ? G HIS 62  ND1 
582 1 Y 1 G HIS 269 ? CD2 ? G HIS 62  CD2 
583 1 Y 1 G HIS 269 ? CE1 ? G HIS 62  CE1 
584 1 Y 1 G HIS 269 ? NE2 ? G HIS 62  NE2 
585 1 Y 1 G ASP 271 ? CG  ? G ASP 64  CG  
586 1 Y 1 G ASP 271 ? OD1 ? G ASP 64  OD1 
587 1 Y 1 G ASP 271 ? OD2 ? G ASP 64  OD2 
588 1 Y 1 G LYS 272 ? CG  ? G LYS 65  CG  
589 1 Y 1 G LYS 272 ? CD  ? G LYS 65  CD  
590 1 Y 1 G LYS 272 ? CE  ? G LYS 65  CE  
591 1 Y 1 G LYS 272 ? NZ  ? G LYS 65  NZ  
592 1 Y 1 G LYS 277 ? CG  ? G LYS 70  CG  
593 1 Y 1 G LYS 277 ? CD  ? G LYS 70  CD  
594 1 Y 1 G LYS 277 ? CE  ? G LYS 70  CE  
595 1 Y 1 G LYS 277 ? NZ  ? G LYS 70  NZ  
596 1 Y 1 G LYS 278 ? CG  ? G LYS 71  CG  
597 1 Y 1 G LYS 278 ? CD  ? G LYS 71  CD  
598 1 Y 1 G LYS 278 ? CE  ? G LYS 71  CE  
599 1 Y 1 G LYS 278 ? NZ  ? G LYS 71  NZ  
600 1 Y 1 G LYS 281 ? CG  ? G LYS 74  CG  
601 1 Y 1 G LYS 281 ? CD  ? G LYS 74  CD  
602 1 Y 1 G LYS 281 ? CE  ? G LYS 74  CE  
603 1 Y 1 G LYS 281 ? NZ  ? G LYS 74  NZ  
604 1 Y 1 G GLU 286 ? CG  ? G GLU 79  CG  
605 1 Y 1 G GLU 286 ? CD  ? G GLU 79  CD  
606 1 Y 1 G GLU 286 ? OE1 ? G GLU 79  OE1 
607 1 Y 1 G GLU 286 ? OE2 ? G GLU 79  OE2 
608 1 Y 1 G GLN 293 ? CG  ? G GLN 86  CG  
609 1 Y 1 G GLN 293 ? CD  ? G GLN 86  CD  
610 1 Y 1 G GLN 293 ? OE1 ? G GLN 86  OE1 
611 1 Y 1 G GLN 293 ? NE2 ? G GLN 86  NE2 
612 1 Y 1 G LYS 310 ? CG  ? G LYS 103 CG  
613 1 Y 1 G LYS 310 ? CD  ? G LYS 103 CD  
614 1 Y 1 G LYS 310 ? CE  ? G LYS 103 CE  
615 1 Y 1 G LYS 310 ? NZ  ? G LYS 103 NZ  
616 1 Y 1 G LYS 312 ? CG  ? G LYS 105 CG  
617 1 Y 1 G LYS 312 ? CD  ? G LYS 105 CD  
618 1 Y 1 G LYS 312 ? CE  ? G LYS 105 CE  
619 1 Y 1 G LYS 312 ? NZ  ? G LYS 105 NZ  
620 1 Y 1 G LYS 322 ? CG  ? G LYS 115 CG  
621 1 Y 1 G LYS 322 ? CD  ? G LYS 115 CD  
622 1 Y 1 G LYS 322 ? CE  ? G LYS 115 CE  
623 1 Y 1 G LYS 322 ? NZ  ? G LYS 115 NZ  
624 1 Y 1 G LYS 335 ? CG  ? G LYS 128 CG  
625 1 Y 1 G LYS 335 ? CD  ? G LYS 128 CD  
626 1 Y 1 G LYS 335 ? CE  ? G LYS 128 CE  
627 1 Y 1 G LYS 335 ? NZ  ? G LYS 128 NZ  
628 1 Y 1 G GLU 336 ? CG  ? G GLU 129 CG  
629 1 Y 1 G GLU 336 ? CD  ? G GLU 129 CD  
630 1 Y 1 G GLU 336 ? OE1 ? G GLU 129 OE1 
631 1 Y 1 G GLU 336 ? OE2 ? G GLU 129 OE2 
632 1 Y 1 G ARG 340 ? CG  ? G ARG 133 CG  
633 1 Y 1 G ARG 340 ? CD  ? G ARG 133 CD  
634 1 Y 1 G ARG 340 ? NE  ? G ARG 133 NE  
635 1 Y 1 G ARG 340 ? CZ  ? G ARG 133 CZ  
636 1 Y 1 G ARG 340 ? NH1 ? G ARG 133 NH1 
637 1 Y 1 G ARG 340 ? NH2 ? G ARG 133 NH2 
638 1 Y 1 G GLU 345 ? CG  ? G GLU 138 CG  
639 1 Y 1 G GLU 345 ? CD  ? G GLU 138 CD  
640 1 Y 1 G GLU 345 ? OE1 ? G GLU 138 OE1 
641 1 Y 1 G GLU 345 ? OE2 ? G GLU 138 OE2 
642 1 Y 1 G LYS 355 ? CG  ? G LYS 148 CG  
643 1 Y 1 G LYS 355 ? CD  ? G LYS 148 CD  
644 1 Y 1 G LYS 355 ? CE  ? G LYS 148 CE  
645 1 Y 1 G LYS 355 ? NZ  ? G LYS 148 NZ  
646 1 Y 1 G LYS 358 ? CG  ? G LYS 151 CG  
647 1 Y 1 G LYS 358 ? CD  ? G LYS 151 CD  
648 1 Y 1 G LYS 358 ? CE  ? G LYS 151 CE  
649 1 Y 1 G LYS 358 ? NZ  ? G LYS 151 NZ  
650 1 Y 1 G PHE 361 ? CG  ? G PHE 154 CG  
651 1 Y 1 G PHE 361 ? CD1 ? G PHE 154 CD1 
652 1 Y 1 G PHE 361 ? CD2 ? G PHE 154 CD2 
653 1 Y 1 G PHE 361 ? CE1 ? G PHE 154 CE1 
654 1 Y 1 G PHE 361 ? CE2 ? G PHE 154 CE2 
655 1 Y 1 G PHE 361 ? CZ  ? G PHE 154 CZ  
656 1 Y 1 G GLU 362 ? CG  ? G GLU 155 CG  
657 1 Y 1 G GLU 362 ? CD  ? G GLU 155 CD  
658 1 Y 1 G GLU 362 ? OE1 ? G GLU 155 OE1 
659 1 Y 1 G GLU 362 ? OE2 ? G GLU 155 OE2 
660 1 Y 1 G ARG 408 ? CG  ? G ARG 201 CG  
661 1 Y 1 G ARG 408 ? CD  ? G ARG 201 CD  
662 1 Y 1 G ARG 408 ? NE  ? G ARG 201 NE  
663 1 Y 1 G ARG 408 ? CZ  ? G ARG 201 CZ  
664 1 Y 1 G ARG 408 ? NH1 ? G ARG 201 NH1 
665 1 Y 1 G ARG 408 ? NH2 ? G ARG 201 NH2 
666 1 Y 1 G MET 410 ? CG  ? G MET 203 CG  
667 1 Y 1 G MET 410 ? SD  ? G MET 203 SD  
668 1 Y 1 G MET 410 ? CE  ? G MET 203 CE  
669 1 Y 1 G GLN 414 ? CG  ? G GLN 207 CG  
670 1 Y 1 G GLN 414 ? CD  ? G GLN 207 CD  
671 1 Y 1 G GLN 414 ? OE1 ? G GLN 207 OE1 
672 1 Y 1 G GLN 414 ? NE2 ? G GLN 207 NE2 
673 1 Y 1 G ARG 424 ? CG  ? G ARG 217 CG  
674 1 Y 1 G ARG 424 ? CD  ? G ARG 217 CD  
675 1 Y 1 G ARG 424 ? NE  ? G ARG 217 NE  
676 1 Y 1 G ARG 424 ? CZ  ? G ARG 217 CZ  
677 1 Y 1 G ARG 424 ? NH1 ? G ARG 217 NH1 
678 1 Y 1 G ARG 424 ? NH2 ? G ARG 217 NH2 
679 1 Y 1 G GLU 426 ? CG  ? G GLU 219 CG  
680 1 Y 1 G GLU 426 ? CD  ? G GLU 219 CD  
681 1 Y 1 G GLU 426 ? OE1 ? G GLU 219 OE1 
682 1 Y 1 G GLU 426 ? OE2 ? G GLU 219 OE2 
683 1 Y 1 G GLN 430 ? CG  ? G GLN 223 CG  
684 1 Y 1 G GLN 430 ? CD  ? G GLN 223 CD  
685 1 Y 1 G GLN 430 ? OE1 ? G GLN 223 OE1 
686 1 Y 1 G GLN 430 ? NE2 ? G GLN 223 NE2 
687 1 Y 1 G LYS 443 ? CG  ? G LYS 236 CG  
688 1 Y 1 G LYS 443 ? CD  ? G LYS 236 CD  
689 1 Y 1 G LYS 443 ? CE  ? G LYS 236 CE  
690 1 Y 1 G LYS 443 ? NZ  ? G LYS 236 NZ  
691 1 Y 1 G TYR 448 ? CG  ? G TYR 241 CG  
692 1 Y 1 G TYR 448 ? CD1 ? G TYR 241 CD1 
693 1 Y 1 G TYR 448 ? CD2 ? G TYR 241 CD2 
694 1 Y 1 G TYR 448 ? CE1 ? G TYR 241 CE1 
695 1 Y 1 G TYR 448 ? CE2 ? G TYR 241 CE2 
696 1 Y 1 G TYR 448 ? CZ  ? G TYR 241 CZ  
697 1 Y 1 G TYR 448 ? OH  ? G TYR 241 OH  
698 1 Y 1 G VAL 455 ? CG1 ? G VAL 248 CG1 
699 1 Y 1 G VAL 455 ? CG2 ? G VAL 248 CG2 
700 1 Y 1 G ASP 459 ? CG  ? G ASP 252 CG  
701 1 Y 1 G ASP 459 ? OD1 ? G ASP 252 OD1 
702 1 Y 1 G ASP 459 ? OD2 ? G ASP 252 OD2 
703 1 Y 1 G TYR 468 ? CG  ? G TYR 261 CG  
704 1 Y 1 G TYR 468 ? CD1 ? G TYR 261 CD1 
705 1 Y 1 G TYR 468 ? CD2 ? G TYR 261 CD2 
706 1 Y 1 G TYR 468 ? CE1 ? G TYR 261 CE1 
707 1 Y 1 G TYR 468 ? CE2 ? G TYR 261 CE2 
708 1 Y 1 G TYR 468 ? CZ  ? G TYR 261 CZ  
709 1 Y 1 G TYR 468 ? OH  ? G TYR 261 OH  
710 1 Y 1 G LYS 472 ? CG  ? G LYS 265 CG  
711 1 Y 1 G LYS 472 ? CD  ? G LYS 265 CD  
712 1 Y 1 G LYS 472 ? CE  ? G LYS 265 CE  
713 1 Y 1 G LYS 472 ? NZ  ? G LYS 265 NZ  
714 1 Y 1 G LYS 476 ? CG  ? G LYS 269 CG  
715 1 Y 1 G LYS 476 ? CD  ? G LYS 269 CD  
716 1 Y 1 G LYS 476 ? CE  ? G LYS 269 CE  
717 1 Y 1 G LYS 476 ? NZ  ? G LYS 269 NZ  
718 1 Y 1 G LYS 479 ? CD  ? G LYS 272 CD  
719 1 Y 1 G LYS 479 ? CE  ? G LYS 272 CE  
720 1 Y 1 G LYS 479 ? NZ  ? G LYS 272 NZ  
721 1 Y 1 G PHE 480 ? CG  ? G PHE 273 CG  
722 1 Y 1 G PHE 480 ? CD1 ? G PHE 273 CD1 
723 1 Y 1 G PHE 480 ? CD2 ? G PHE 273 CD2 
724 1 Y 1 G PHE 480 ? CE1 ? G PHE 273 CE1 
725 1 Y 1 G PHE 480 ? CE2 ? G PHE 273 CE2 
726 1 Y 1 G PHE 480 ? CZ  ? G PHE 273 CZ  
727 1 Y 1 G VAL 484 ? CG1 ? G VAL 277 CG1 
728 1 Y 1 G VAL 484 ? CG2 ? G VAL 277 CG2 
729 1 Y 1 G VAL 485 ? CG1 ? G VAL 278 CG1 
730 1 Y 1 G VAL 485 ? CG2 ? G VAL 278 CG2 
731 1 Y 1 G ARG 487 ? CG  ? G ARG 280 CG  
732 1 Y 1 G ARG 487 ? CD  ? G ARG 280 CD  
733 1 Y 1 G ARG 487 ? NE  ? G ARG 280 NE  
734 1 Y 1 G ARG 487 ? CZ  ? G ARG 280 CZ  
735 1 Y 1 G ARG 487 ? NH1 ? G ARG 280 NH1 
736 1 Y 1 G ARG 487 ? NH2 ? G ARG 280 NH2 
737 1 Y 1 G LYS 490 ? CG  ? G LYS 283 CG  
738 1 Y 1 G LYS 490 ? CD  ? G LYS 283 CD  
739 1 Y 1 G LYS 490 ? CE  ? G LYS 283 CE  
740 1 Y 1 G LYS 490 ? NZ  ? G LYS 283 NZ  
741 1 Y 1 G GLU 491 ? CG  ? G GLU 284 CG  
742 1 Y 1 G GLU 491 ? CD  ? G GLU 284 CD  
743 1 Y 1 G GLU 491 ? OE1 ? G GLU 284 OE1 
744 1 Y 1 G GLU 491 ? OE2 ? G GLU 284 OE2 
745 1 Y 1 G GLU 495 ? CG  ? G GLU 288 CG  
746 1 Y 1 G GLU 495 ? CD  ? G GLU 288 CD  
747 1 Y 1 G GLU 495 ? OE1 ? G GLU 288 OE1 
748 1 Y 1 G GLU 495 ? OE2 ? G GLU 288 OE2 
749 1 Y 1 G HIS 496 ? CG  ? G HIS 289 CG  
750 1 Y 1 G HIS 496 ? ND1 ? G HIS 289 ND1 
751 1 Y 1 G HIS 496 ? CD2 ? G HIS 289 CD2 
752 1 Y 1 G HIS 496 ? CE1 ? G HIS 289 CE1 
753 1 Y 1 G HIS 496 ? NE2 ? G HIS 289 NE2 
754 1 Y 1 G TYR 498 ? CG  ? G TYR 291 CG  
755 1 Y 1 G TYR 498 ? CD1 ? G TYR 291 CD1 
756 1 Y 1 G TYR 498 ? CD2 ? G TYR 291 CD2 
757 1 Y 1 G TYR 498 ? CE1 ? G TYR 291 CE1 
758 1 Y 1 G TYR 498 ? CE2 ? G TYR 291 CE2 
759 1 Y 1 G TYR 498 ? CZ  ? G TYR 291 CZ  
760 1 Y 1 G TYR 498 ? OH  ? G TYR 291 OH  
761 1 Y 1 G ARG 508 ? CG  ? G ARG 301 CG  
762 1 Y 1 G ARG 508 ? CD  ? G ARG 301 CD  
763 1 Y 1 G ARG 508 ? NE  ? G ARG 301 NE  
764 1 Y 1 G ARG 508 ? CZ  ? G ARG 301 CZ  
765 1 Y 1 G ARG 508 ? NH1 ? G ARG 301 NH1 
766 1 Y 1 G ARG 508 ? NH2 ? G ARG 301 NH2 
767 1 Y 1 G HIS 509 ? CG  ? G HIS 302 CG  
768 1 Y 1 G HIS 509 ? ND1 ? G HIS 302 ND1 
769 1 Y 1 G HIS 509 ? CD2 ? G HIS 302 CD2 
770 1 Y 1 G HIS 509 ? CE1 ? G HIS 302 CE1 
771 1 Y 1 G HIS 509 ? NE2 ? G HIS 302 NE2 
772 1 Y 1 G ARG 520 ? CG  ? G ARG 313 CG  
773 1 Y 1 G ARG 520 ? CD  ? G ARG 313 CD  
774 1 Y 1 G ARG 520 ? NE  ? G ARG 313 NE  
775 1 Y 1 G ARG 520 ? CZ  ? G ARG 313 CZ  
776 1 Y 1 G ARG 520 ? NH1 ? G ARG 313 NH1 
777 1 Y 1 G ARG 520 ? NH2 ? G ARG 313 NH2 
778 1 Y 1 G LYS 523 ? CG  ? G LYS 316 CG  
779 1 Y 1 G LYS 523 ? CD  ? G LYS 316 CD  
780 1 Y 1 G LYS 523 ? CE  ? G LYS 316 CE  
781 1 Y 1 G LYS 523 ? NZ  ? G LYS 316 NZ  
782 1 Y 1 G LEU 528 ? CG  ? G LEU 321 CG  
783 1 Y 1 G LEU 528 ? CD1 ? G LEU 321 CD1 
784 1 Y 1 G LEU 528 ? CD2 ? G LEU 321 CD2 
785 1 Y 1 G GLN 529 ? CG  ? G GLN 322 CG  
786 1 Y 1 G GLN 529 ? CD  ? G GLN 322 CD  
787 1 Y 1 G GLN 529 ? OE1 ? G GLN 322 OE1 
788 1 Y 1 G GLN 529 ? NE2 ? G GLN 322 NE2 
789 1 Y 1 H LYS 6   ? CG  ? H LYS 6   CG  
790 1 Y 1 H LYS 6   ? CD  ? H LYS 6   CD  
791 1 Y 1 H LYS 6   ? CE  ? H LYS 6   CE  
792 1 Y 1 H LYS 6   ? NZ  ? H LYS 6   NZ  
793 1 Y 1 H LYS 11  ? CG  ? H LYS 11  CG  
794 1 Y 1 H LYS 11  ? CD  ? H LYS 11  CD  
795 1 Y 1 H LYS 11  ? CE  ? H LYS 11  CE  
796 1 Y 1 H LYS 11  ? NZ  ? H LYS 11  NZ  
797 1 Y 1 H GLN 40  ? CG  ? H GLN 40  CG  
798 1 Y 1 H GLN 40  ? CD  ? H GLN 40  CD  
799 1 Y 1 H GLN 40  ? OE1 ? H GLN 40  OE1 
800 1 Y 1 H GLN 40  ? NE2 ? H GLN 40  NE2 
801 1 Y 1 H LYS 48  ? CG  ? H LYS 48  CG  
802 1 Y 1 H LYS 48  ? CD  ? H LYS 48  CD  
803 1 Y 1 H LYS 48  ? CE  ? H LYS 48  CE  
804 1 Y 1 H LYS 48  ? NZ  ? H LYS 48  NZ  
805 1 Y 1 H ARG 54  ? CG  ? H ARG 54  CG  
806 1 Y 1 H ARG 54  ? CD  ? H ARG 54  CD  
807 1 Y 1 H ARG 54  ? NE  ? H ARG 54  NE  
808 1 Y 1 H ARG 54  ? CZ  ? H ARG 54  CZ  
809 1 Y 1 H ARG 54  ? NH1 ? H ARG 54  NH1 
810 1 Y 1 H ARG 54  ? NH2 ? H ARG 54  NH2 
811 1 N 1 C XB7 601 ? C1  ? I XB7 1   C1  
812 1 N 1 C XB7 601 ? C2  ? I XB7 1   C2  
813 1 N 1 C XB7 601 ? C27 ? I XB7 1   C27 
814 1 N 1 C XB7 601 ? C28 ? I XB7 1   C28 
815 1 N 1 C XB7 601 ? C3  ? I XB7 1   C3  
816 1 N 1 C XB7 601 ? C4  ? I XB7 1   C4  
817 1 N 1 C XB7 601 ? C5  ? I XB7 1   C5  
818 1 N 1 C XB7 601 ? C6  ? I XB7 1   C6  
819 1 N 1 C XB7 601 ? C7  ? I XB7 1   C7  
820 1 N 1 C XB7 601 ? O1  ? I XB7 1   O1  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.16_3549: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                  2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .                  3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? .                  4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.11 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9IML 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     101.570 
_cell.length_a_esd                 ? 
_cell.length_b                     84.970 
_cell.length_b_esd                 ? 
_cell.length_c                     106.990 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9IML 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9IML 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.33 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          47.22 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Bis-tris pH 6.5, 0.2 M MgCl2, 25% PEG3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-07-02 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9792 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL02U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9792 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL02U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9IML 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.78 
_reflns.d_resolution_low                               33.67 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     45859 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.21 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          16.67 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.03838 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.78 
_reflns_shell.d_res_low                                     2.879 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4436 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.3814 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9IML 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.780 
_refine.ls_d_res_low                             33.670 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     45737 
_refine.ls_number_reflns_R_free                  2277 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.28 
_refine.ls_percent_reflns_R_free                 4.98 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2239 
_refine.ls_R_factor_R_free                       0.2803 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2208 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      1NBF 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 32.55 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.47 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.780 
_refine_hist.d_res_low                        33.670 
_refine_hist.number_atoms_solvent             43 
_refine_hist.number_atoms_total               11753 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        11686 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         24 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
_refine_ls_shell.R_factor_R_free                  0.2714 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.2328 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.d_res_high                       2.78 
_refine_ls_shell.d_res_low                        2.88 
_refine_ls_shell.number_reflns_R_free             ? 
_refine_ls_shell.number_reflns_R_work             ? 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                4436 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.pdbx_total_number_of_bins_used   ? 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.percent_reflns_obs               97.09 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
# 
_struct.entry_id                     9IML 
_struct.title                        
'Sertraline enhances the deubiquitinase activity of USP7 by binding to its switching loop region' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9IML 
_struct_keywords.text            'ubiquitin specific protease, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 1 ? 
F N N 2 ? 
G N N 1 ? 
H N N 2 ? 
I N N 3 ? 
J N N 4 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
N N N 4 ? 
O N N 4 ? 
P N N 4 ? 
Q N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP UBP7_HUMAN  Q93009 ? 1 
;KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWET
LDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDY
VAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN
YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEV
LQAVTDHDIPQQLVERLQEEKRIEAQKRKERQE
;
208 
2 UNP RS27A_HUMAN P62979 ? 2 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9IML A 1 ? 353 ? Q93009 208 ? 560 ? 208 560 
2 2 9IML B 1 ? 75  ? P62979 1   ? 75  ? 1   75  
3 1 9IML C 1 ? 353 ? Q93009 208 ? 560 ? 208 560 
4 2 9IML D 1 ? 75  ? P62979 1   ? 75  ? 1   75  
5 1 9IML E 1 ? 353 ? Q93009 208 ? 560 ? 208 560 
6 2 9IML F 1 ? 75  ? P62979 1   ? 75  ? 1   75  
7 1 9IML G 1 ? 353 ? Q93009 208 ? 560 ? 208 560 
8 2 9IML H 1 ? 75  ? P62979 1   ? 75  ? 1   75  
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
3 author_and_software_defined_assembly PISA dimeric 2 
4 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3290  ? 
1 MORE         -5    ? 
1 'SSA (A^2)'  15900 ? 
2 'ABSA (A^2)' 3080  ? 
2 MORE         -7    ? 
2 'SSA (A^2)'  15200 ? 
3 'ABSA (A^2)' 3210  ? 
3 MORE         -4    ? 
3 'SSA (A^2)'  16040 ? 
4 'ABSA (A^2)' 3150  ? 
4 MORE         -7    ? 
4 'SSA (A^2)'  15570 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,J,K   
2 1 C,D,I,L,M 
3 1 E,F,N,O   
4 1 G,H,P,Q   
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 15  ? THR A 28  ? THR A 222 THR A 235 1 ? 14 
HELX_P HELX_P2  AA2 THR A 28  ? MET A 37  ? THR A 235 MET A 244 1 ? 10 
HELX_P HELX_P3  AA3 SER A 48  ? SER A 63  ? SER A 255 SER A 270 1 ? 16 
HELX_P HELX_P4  AA4 THR A 69  ? PHE A 76  ? THR A 276 PHE A 283 1 ? 8  
HELX_P HELX_P5  AA5 LEU A 81  ? MET A 85  ? LEU A 288 MET A 292 5 ? 5  
HELX_P HELX_P6  AA6 ASP A 88  ? MET A 104 ? ASP A 295 MET A 311 1 ? 17 
HELX_P HELX_P7  AA7 GLY A 111 ? ARG A 118 ? GLY A 318 ARG A 325 1 ? 8  
HELX_P HELX_P8  AA8 ASN A 152 ? ALA A 162 ? ASN A 359 ALA A 369 1 ? 11 
HELX_P HELX_P9  AA9 ASP A 167 ? LYS A 171 ? ASP A 374 LYS A 378 5 ? 5  
HELX_P HELX_P10 AB1 GLY A 175 ? HIS A 177 ? GLY A 382 HIS A 384 5 ? 3  
HELX_P HELX_P11 AB2 ASP A 227 ? LEU A 230 ? ASP A 434 LEU A 437 5 ? 4  
HELX_P HELX_P12 AB3 THR A 282 ? ILE A 287 ? THR A 489 ILE A 494 1 ? 6  
HELX_P HELX_P13 AB4 GLU A 288 ? TYR A 291 ? GLU A 495 TYR A 498 5 ? 4  
HELX_P HELX_P14 AB5 LYS A 316 ? LEU A 321 ? LYS A 523 LEU A 528 1 ? 6  
HELX_P HELX_P15 AB6 THR A 325 ? ILE A 329 ? THR A 532 ILE A 536 5 ? 5  
HELX_P HELX_P16 AB7 PRO A 330 ? GLU A 339 ? PRO A 537 GLU A 546 1 ? 10 
HELX_P HELX_P17 AB8 THR B 22  ? GLY B 35  ? THR B 22  GLY B 35  1 ? 14 
HELX_P HELX_P18 AB9 PRO B 37  ? GLN B 41  ? PRO B 37  GLN B 41  5 ? 5  
HELX_P HELX_P19 AC1 THR B 55  ? ASN B 60  ? THR B 55  ASN B 60  5 ? 6  
HELX_P HELX_P20 AC2 THR C 15  ? PHE C 27  ? THR C 222 PHE C 234 1 ? 13 
HELX_P HELX_P21 AC3 THR C 28  ? MET C 37  ? THR C 235 MET C 244 1 ? 10 
HELX_P HELX_P22 AC4 SER C 48  ? SER C 63  ? SER C 255 SER C 270 1 ? 16 
HELX_P HELX_P23 AC5 THR C 69  ? PHE C 76  ? THR C 276 PHE C 283 1 ? 8  
HELX_P HELX_P24 AC6 THR C 80  ? MET C 85  ? THR C 287 MET C 292 5 ? 6  
HELX_P HELX_P25 AC7 ASP C 88  ? MET C 104 ? ASP C 295 MET C 311 1 ? 17 
HELX_P HELX_P26 AC8 GLY C 111 ? ARG C 118 ? GLY C 318 ARG C 325 1 ? 8  
HELX_P HELX_P27 AC9 ASN C 152 ? ALA C 162 ? ASN C 359 ALA C 369 1 ? 11 
HELX_P HELX_P28 AD1 ASP C 167 ? LYS C 171 ? ASP C 374 LYS C 378 5 ? 5  
HELX_P HELX_P29 AD2 GLY C 175 ? HIS C 177 ? GLY C 382 HIS C 384 5 ? 3  
HELX_P HELX_P30 AD3 ASP C 227 ? LEU C 230 ? ASP C 434 LEU C 437 5 ? 4  
HELX_P HELX_P31 AD4 THR C 282 ? ILE C 287 ? THR C 489 ILE C 494 1 ? 6  
HELX_P HELX_P32 AD5 GLU C 288 ? TYR C 291 ? GLU C 495 TYR C 498 5 ? 4  
HELX_P HELX_P33 AD6 LYS C 316 ? LEU C 321 ? LYS C 523 LEU C 528 1 ? 6  
HELX_P HELX_P34 AD7 THR C 325 ? ILE C 329 ? THR C 532 ILE C 536 5 ? 5  
HELX_P HELX_P35 AD8 THR D 22  ? GLY D 35  ? THR D 22  GLY D 35  1 ? 14 
HELX_P HELX_P36 AD9 LEU D 56  ? ASN D 60  ? LEU D 56  ASN D 60  5 ? 5  
HELX_P HELX_P37 AE1 THR E 15  ? PHE E 27  ? THR E 222 PHE E 234 1 ? 13 
HELX_P HELX_P38 AE2 THR E 28  ? MET E 37  ? THR E 235 MET E 244 1 ? 10 
HELX_P HELX_P39 AE3 SER E 48  ? SER E 63  ? SER E 255 SER E 270 1 ? 16 
HELX_P HELX_P40 AE4 THR E 69  ? PHE E 76  ? THR E 276 PHE E 283 1 ? 8  
HELX_P HELX_P41 AE5 GLU E 79  ? MET E 85  ? GLU E 286 MET E 292 5 ? 7  
HELX_P HELX_P42 AE6 ASP E 88  ? MET E 104 ? ASP E 295 MET E 311 1 ? 17 
HELX_P HELX_P43 AE7 GLY E 111 ? ARG E 118 ? GLY E 318 ARG E 325 1 ? 8  
HELX_P HELX_P44 AE8 ASN E 152 ? VAL E 161 ? ASN E 359 VAL E 368 1 ? 10 
HELX_P HELX_P45 AE9 ASP E 167 ? LYS E 171 ? ASP E 374 LYS E 378 5 ? 5  
HELX_P HELX_P46 AF1 GLY E 175 ? HIS E 177 ? GLY E 382 HIS E 384 5 ? 3  
HELX_P HELX_P47 AF2 ASP E 227 ? LEU E 230 ? ASP E 434 LEU E 437 5 ? 4  
HELX_P HELX_P48 AF3 ILE E 287 ? TYR E 291 ? ILE E 494 TYR E 498 5 ? 5  
HELX_P HELX_P49 AF4 GLU E 314 ? LEU E 321 ? GLU E 521 LEU E 528 1 ? 8  
HELX_P HELX_P50 AF5 PRO E 330 ? GLU E 339 ? PRO E 537 GLU E 546 1 ? 10 
HELX_P HELX_P51 AF6 THR F 22  ? GLY F 35  ? THR F 22  GLY F 35  1 ? 14 
HELX_P HELX_P52 AF7 PRO F 37  ? GLN F 41  ? PRO F 37  GLN F 41  5 ? 5  
HELX_P HELX_P53 AF8 THR F 55  ? ASN F 60  ? THR F 55  ASN F 60  5 ? 6  
HELX_P HELX_P54 AF9 THR G 15  ? PHE G 27  ? THR G 222 PHE G 234 1 ? 13 
HELX_P HELX_P55 AG1 THR G 28  ? MET G 37  ? THR G 235 MET G 244 1 ? 10 
HELX_P HELX_P56 AG2 SER G 48  ? LEU G 60  ? SER G 255 LEU G 267 1 ? 13 
HELX_P HELX_P57 AG3 THR G 69  ? PHE G 76  ? THR G 276 PHE G 283 1 ? 8  
HELX_P HELX_P58 AG4 THR G 80  ? MET G 85  ? THR G 287 MET G 292 5 ? 6  
HELX_P HELX_P59 AG5 VAL G 89  ? MET G 104 ? VAL G 296 MET G 311 1 ? 16 
HELX_P HELX_P60 AG6 GLY G 111 ? ARG G 118 ? GLY G 318 ARG G 325 1 ? 8  
HELX_P HELX_P61 AG7 ASN G 152 ? VAL G 161 ? ASN G 359 VAL G 368 1 ? 10 
HELX_P HELX_P62 AG8 ASP G 167 ? LYS G 171 ? ASP G 374 LYS G 378 5 ? 5  
HELX_P HELX_P63 AG9 GLY G 175 ? HIS G 177 ? GLY G 382 HIS G 384 5 ? 3  
HELX_P HELX_P64 AH1 ASP G 227 ? LEU G 230 ? ASP G 434 LEU G 437 5 ? 4  
HELX_P HELX_P65 AH2 ILE G 287 ? TYR G 291 ? ILE G 494 TYR G 498 5 ? 5  
HELX_P HELX_P66 AH3 VAL G 300 ? HIS G 302 ? VAL G 507 HIS G 509 5 ? 3  
HELX_P HELX_P67 AH4 LYS G 316 ? LEU G 321 ? LYS G 523 LEU G 528 1 ? 6  
HELX_P HELX_P68 AH5 THR H 22  ? GLY H 35  ? THR H 22  GLY H 35  1 ? 14 
HELX_P HELX_P69 AH6 LEU H 56  ? ASN H 60  ? LEU H 56  ASN H 60  5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 7 ? 
AA4 ? 2 ? 
AA5 ? 5 ? 
AA6 ? 4 ? 
AA7 ? 5 ? 
AA8 ? 7 ? 
AA9 ? 2 ? 
AB1 ? 5 ? 
AB2 ? 4 ? 
AB3 ? 5 ? 
AB4 ? 7 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
AB7 ? 5 ? 
AB8 ? 2 ? 
AB9 ? 4 ? 
AC1 ? 5 ? 
AC2 ? 7 ? 
AC3 ? 2 ? 
AC4 ? 2 ? 
AC5 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? parallel      
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA8 6 7 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? parallel      
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB4 6 7 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? parallel      
AB7 3 4 ? anti-parallel 
AB7 4 5 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? parallel      
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC1 4 5 ? anti-parallel 
AC2 1 2 ? parallel      
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC2 4 5 ? anti-parallel 
AC2 5 6 ? anti-parallel 
AC2 6 7 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? parallel      
AC5 3 4 ? anti-parallel 
AC5 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 133 ? TYR A 140 ? ARG A 340 TYR A 347 
AA1 2 GLY A 119 ? CYS A 127 ? GLY A 326 CYS A 334 
AA1 3 ALA A 182 ? THR A 190 ? ALA A 389 THR A 397 
AA1 4 VAL A 163 ? LEU A 166 ? VAL A 370 LEU A 373 
AA2 1 ILE A 143 ? LEU A 145 ? ILE A 350 LEU A 352 
AA2 2 VAL A 194 ? LEU A 199 ? VAL A 401 LEU A 406 
AA2 3 THR A 304 ? ARG A 313 ? THR A 511 ARG A 520 
AA2 4 ASN A 240 ? SER A 250 ? ASN A 447 SER A 457 
AA2 5 GLN A 223 ? PRO A 225 ? GLN A 430 PRO A 432 
AA3 1 ILE A 143 ? LEU A 145 ? ILE A 350 LEU A 352 
AA3 2 VAL A 194 ? LEU A 199 ? VAL A 401 LEU A 406 
AA3 3 THR A 304 ? ARG A 313 ? THR A 511 ARG A 520 
AA3 4 ASN A 240 ? SER A 250 ? ASN A 447 SER A 457 
AA3 5 HIS A 257 ? LEU A 262 ? HIS A 464 LEU A 469 
AA3 6 CYS A 271 ? ASP A 274 ? CYS A 478 ASP A 481 
AA3 7 VAL A 277 ? ARG A 280 ? VAL A 484 ARG A 487 
AA4 1 TYR A 172 ? ASP A 173 ? TYR A 379 ASP A 380 
AA4 2 LEU A 179 ? GLN A 180 ? LEU A 386 GLN A 387 
AA5 1 THR B 12  ? GLU B 16  ? THR B 12  GLU B 16  
AA5 2 GLN B 2   ? LYS B 6   ? GLN B 2   LYS B 6   
AA5 3 THR B 66  ? VAL B 70  ? THR B 66  VAL B 70  
AA5 4 ARG B 42  ? PHE B 45  ? ARG B 42  PHE B 45  
AA5 5 LYS B 48  ? GLN B 49  ? LYS B 48  GLN B 49  
AA6 1 ARG C 133 ? TYR C 140 ? ARG C 340 TYR C 347 
AA6 2 GLY C 119 ? CYS C 127 ? GLY C 326 CYS C 334 
AA6 3 ALA C 182 ? THR C 190 ? ALA C 389 THR C 397 
AA6 4 GLU C 164 ? LEU C 166 ? GLU C 371 LEU C 373 
AA7 1 ILE C 143 ? SER C 146 ? ILE C 350 SER C 353 
AA7 2 VAL C 194 ? MET C 200 ? VAL C 401 MET C 407 
AA7 3 THR C 304 ? ARG C 313 ? THR C 511 ARG C 520 
AA7 4 ASN C 240 ? GLY C 251 ? ASN C 447 GLY C 458 
AA7 5 GLN C 223 ? PRO C 225 ? GLN C 430 PRO C 432 
AA8 1 ILE C 143 ? SER C 146 ? ILE C 350 SER C 353 
AA8 2 VAL C 194 ? MET C 200 ? VAL C 401 MET C 407 
AA8 3 THR C 304 ? ARG C 313 ? THR C 511 ARG C 520 
AA8 4 ASN C 240 ? GLY C 251 ? ASN C 447 GLY C 458 
AA8 5 GLY C 256 ? LEU C 262 ? GLY C 463 LEU C 469 
AA8 6 CYS C 271 ? ASP C 274 ? CYS C 478 ASP C 481 
AA8 7 VAL C 277 ? ARG C 280 ? VAL C 484 ARG C 487 
AA9 1 TYR C 172 ? ASP C 173 ? TYR C 379 ASP C 380 
AA9 2 LEU C 179 ? GLN C 180 ? LEU C 386 GLN C 387 
AB1 1 THR D 12  ? GLU D 16  ? THR D 12  GLU D 16  
AB1 2 GLN D 2   ? LYS D 6   ? GLN D 2   LYS D 6   
AB1 3 THR D 66  ? VAL D 70  ? THR D 66  VAL D 70  
AB1 4 ARG D 42  ? PHE D 45  ? ARG D 42  PHE D 45  
AB1 5 LYS D 48  ? GLN D 49  ? LYS D 48  GLN D 49  
AB2 1 ARG E 133 ? TYR E 140 ? ARG E 340 TYR E 347 
AB2 2 GLY E 119 ? CYS E 127 ? GLY E 326 CYS E 334 
AB2 3 ALA E 182 ? THR E 190 ? ALA E 389 THR E 397 
AB2 4 GLU E 164 ? LEU E 166 ? GLU E 371 LEU E 373 
AB3 1 ILE E 143 ? SER E 146 ? ILE E 350 SER E 353 
AB3 2 VAL E 194 ? MET E 200 ? VAL E 401 MET E 407 
AB3 3 THR E 304 ? ARG E 313 ? THR E 511 ARG E 520 
AB3 4 ASN E 240 ? GLY E 251 ? ASN E 447 GLY E 458 
AB3 5 GLN E 223 ? PRO E 225 ? GLN E 430 PRO E 432 
AB4 1 ILE E 143 ? SER E 146 ? ILE E 350 SER E 353 
AB4 2 VAL E 194 ? MET E 200 ? VAL E 401 MET E 407 
AB4 3 THR E 304 ? ARG E 313 ? THR E 511 ARG E 520 
AB4 4 ASN E 240 ? GLY E 251 ? ASN E 447 GLY E 458 
AB4 5 GLY E 256 ? LEU E 262 ? GLY E 463 LEU E 469 
AB4 6 CYS E 271 ? ASP E 274 ? CYS E 478 ASP E 481 
AB4 7 VAL E 277 ? ARG E 280 ? VAL E 484 ARG E 487 
AB5 1 TYR E 172 ? ASP E 173 ? TYR E 379 ASP E 380 
AB5 2 LEU E 179 ? GLN E 180 ? LEU E 386 GLN E 387 
AB6 1 PHE E 202 ? MET E 203 ? PHE E 409 MET E 410 
AB6 2 ILE E 212 ? LYS E 213 ? ILE E 419 LYS E 420 
AB7 1 THR F 12  ? GLU F 16  ? THR F 12  GLU F 16  
AB7 2 GLN F 2   ? LYS F 6   ? GLN F 2   LYS F 6   
AB7 3 THR F 66  ? VAL F 70  ? THR F 66  VAL F 70  
AB7 4 ARG F 42  ? PHE F 45  ? ARG F 42  PHE F 45  
AB7 5 LYS F 48  ? GLN F 49  ? LYS F 48  GLN F 49  
AB8 1 HIS G 87  ? ASP G 88  ? HIS G 294 ASP G 295 
AB8 2 ARG H 74  ? GLY H 75  ? ARG H 74  GLY H 75  
AB9 1 ARG G 133 ? TYR G 140 ? ARG G 340 TYR G 347 
AB9 2 GLY G 119 ? CYS G 127 ? GLY G 326 CYS G 334 
AB9 3 ALA G 182 ? THR G 190 ? ALA G 389 THR G 397 
AB9 4 GLU G 164 ? LEU G 166 ? GLU G 371 LEU G 373 
AC1 1 ILE G 143 ? SER G 146 ? ILE G 350 SER G 353 
AC1 2 VAL G 194 ? MET G 200 ? VAL G 401 MET G 407 
AC1 3 THR G 304 ? ARG G 313 ? THR G 511 ARG G 520 
AC1 4 ASN G 240 ? GLY G 251 ? ASN G 447 GLY G 458 
AC1 5 GLN G 223 ? PRO G 225 ? GLN G 430 PRO G 432 
AC2 1 ILE G 143 ? SER G 146 ? ILE G 350 SER G 353 
AC2 2 VAL G 194 ? MET G 200 ? VAL G 401 MET G 407 
AC2 3 THR G 304 ? ARG G 313 ? THR G 511 ARG G 520 
AC2 4 ASN G 240 ? GLY G 251 ? ASN G 447 GLY G 458 
AC2 5 GLY G 256 ? LEU G 262 ? GLY G 463 LEU G 469 
AC2 6 CYS G 271 ? ASP G 274 ? CYS G 478 ASP G 481 
AC2 7 VAL G 277 ? ARG G 280 ? VAL G 484 ARG G 487 
AC3 1 TYR G 172 ? ASP G 173 ? TYR G 379 ASP G 380 
AC3 2 LEU G 179 ? GLN G 180 ? LEU G 386 GLN G 387 
AC4 1 PHE G 202 ? ASP G 205 ? PHE G 409 ASP G 412 
AC4 2 THR G 208 ? THR G 208 ? THR G 415 THR G 415 
AC5 1 THR H 12  ? GLU H 16  ? THR H 12  GLU H 16  
AC5 2 GLN H 2   ? LYS H 6   ? GLN H 2   LYS H 6   
AC5 3 THR H 66  ? VAL H 70  ? THR H 66  VAL H 70  
AC5 4 ARG H 42  ? PHE H 45  ? ARG H 42  PHE H 45  
AC5 5 LYS H 48  ? GLN H 49  ? LYS H 48  GLN H 49  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O TYR A 140 ? O TYR A 347 N GLY A 119 ? N GLY A 326 
AA1 2 3 N TYR A 124 ? N TYR A 331 O GLY A 185 ? O GLY A 392 
AA1 3 4 O LYS A 184 ? O LYS A 391 N GLU A 164 ? N GLU A 371 
AA2 1 2 N ILE A 143 ? N ILE A 350 O GLN A 198 ? O GLN A 405 
AA2 2 3 N LEU A 195 ? N LEU A 402 O TYR A 311 ? O TYR A 518 
AA2 3 4 O VAL A 310 ? O VAL A 517 N HIS A 244 ? N HIS A 451 
AA2 4 5 O TYR A 241 ? O TYR A 448 N LEU A 224 ? N LEU A 431 
AA3 1 2 N ILE A 143 ? N ILE A 350 O GLN A 198 ? O GLN A 405 
AA3 2 3 N LEU A 195 ? N LEU A 402 O TYR A 311 ? O TYR A 518 
AA3 3 4 O VAL A 310 ? O VAL A 517 N HIS A 244 ? N HIS A 451 
AA3 4 5 N VAL A 248 ? N VAL A 455 O VAL A 259 ? O VAL A 466 
AA3 5 6 N LEU A 262 ? N LEU A 469 O CYS A 271 ? O CYS A 478 
AA3 6 7 N ASP A 274 ? N ASP A 481 O VAL A 277 ? O VAL A 484 
AA4 1 2 N TYR A 172 ? N TYR A 379 O GLN A 180 ? O GLN A 387 
AA5 1 2 O ILE B 13  ? O ILE B 13  N VAL B 5   ? N VAL B 5   
AA5 2 3 N LYS B 6   ? N LYS B 6   O LEU B 67  ? O LEU B 67  
AA5 3 4 O HIS B 68  ? O HIS B 68  N ILE B 44  ? N ILE B 44  
AA5 4 5 N PHE B 45  ? N PHE B 45  O LYS B 48  ? O LYS B 48  
AA6 1 2 O ARG C 136 ? O ARG C 343 N SER C 123 ? N SER C 330 
AA6 2 3 N TYR C 124 ? N TYR C 331 O GLY C 185 ? O GLY C 392 
AA6 3 4 O ALA C 182 ? O ALA C 389 N LEU C 166 ? N LEU C 373 
AA7 1 2 N ILE C 143 ? N ILE C 350 O GLN C 198 ? O GLN C 405 
AA7 2 3 N LEU C 195 ? N LEU C 402 O TYR C 311 ? O TYR C 518 
AA7 3 4 O VAL C 310 ? O VAL C 517 N HIS C 244 ? N HIS C 451 
AA7 4 5 O TYR C 241 ? O TYR C 448 N LEU C 224 ? N LEU C 431 
AA8 1 2 N ILE C 143 ? N ILE C 350 O GLN C 198 ? O GLN C 405 
AA8 2 3 N LEU C 195 ? N LEU C 402 O TYR C 311 ? O TYR C 518 
AA8 3 4 O VAL C 310 ? O VAL C 517 N HIS C 244 ? N HIS C 451 
AA8 4 5 N VAL C 248 ? N VAL C 455 O VAL C 259 ? O VAL C 466 
AA8 5 6 N VAL C 260 ? N VAL C 467 O PHE C 273 ? O PHE C 480 
AA8 6 7 N LYS C 272 ? N LYS C 479 O SER C 279 ? O SER C 486 
AA9 1 2 N TYR C 172 ? N TYR C 379 O GLN C 180 ? O GLN C 387 
AB1 1 2 O ILE D 13  ? O ILE D 13  N VAL D 5   ? N VAL D 5   
AB1 2 3 N PHE D 4   ? N PHE D 4   O LEU D 67  ? O LEU D 67  
AB1 3 4 O HIS D 68  ? O HIS D 68  N ILE D 44  ? N ILE D 44  
AB1 4 5 N PHE D 45  ? N PHE D 45  O LYS D 48  ? O LYS D 48  
AB2 1 2 O GLU E 138 ? O GLU E 345 N MET E 121 ? N MET E 328 
AB2 2 3 N LYS E 120 ? N LYS E 327 O LEU E 189 ? O LEU E 396 
AB2 3 4 O ALA E 182 ? O ALA E 389 N LEU E 166 ? N LEU E 373 
AB3 1 2 N ILE E 143 ? N ILE E 350 O GLN E 198 ? O GLN E 405 
AB3 2 3 N LEU E 199 ? N LEU E 406 O TYR E 307 ? O TYR E 514 
AB3 3 4 O ILE E 312 ? O ILE E 519 N ILE E 242 ? N ILE E 449 
AB3 4 5 O TYR E 241 ? O TYR E 448 N LEU E 224 ? N LEU E 431 
AB4 1 2 N ILE E 143 ? N ILE E 350 O GLN E 198 ? O GLN E 405 
AB4 2 3 N LEU E 199 ? N LEU E 406 O TYR E 307 ? O TYR E 514 
AB4 3 4 O ILE E 312 ? O ILE E 519 N ILE E 242 ? N ILE E 449 
AB4 4 5 N VAL E 248 ? N VAL E 455 O VAL E 259 ? O VAL E 466 
AB4 5 6 N LEU E 262 ? N LEU E 469 O CYS E 271 ? O CYS E 478 
AB4 6 7 N LYS E 272 ? N LYS E 479 O SER E 279 ? O SER E 486 
AB5 1 2 N TYR E 172 ? N TYR E 379 O GLN E 180 ? O GLN E 387 
AB6 1 2 N MET E 203 ? N MET E 410 O ILE E 212 ? O ILE E 419 
AB7 1 2 O ILE F 13  ? O ILE F 13  N VAL F 5   ? N VAL F 5   
AB7 2 3 N LYS F 6   ? N LYS F 6   O LEU F 67  ? O LEU F 67  
AB7 3 4 O HIS F 68  ? O HIS F 68  N ILE F 44  ? N ILE F 44  
AB7 4 5 N PHE F 45  ? N PHE F 45  O LYS F 48  ? O LYS F 48  
AB8 1 2 N HIS G 87  ? N HIS G 294 O GLY H 75  ? O GLY H 75  
AB9 1 2 O ARG G 136 ? O ARG G 343 N SER G 123 ? N SER G 330 
AB9 2 3 N TYR G 124 ? N TYR G 331 O GLY G 185 ? O GLY G 392 
AB9 3 4 O LYS G 184 ? O LYS G 391 N GLU G 164 ? N GLU G 371 
AC1 1 2 N ILE G 143 ? N ILE G 350 O GLN G 198 ? O GLN G 405 
AC1 2 3 N LEU G 197 ? N LEU G 404 O LEU G 309 ? O LEU G 516 
AC1 3 4 O TYR G 307 ? O TYR G 514 N LEU G 247 ? N LEU G 454 
AC1 4 5 O TYR G 241 ? O TYR G 448 N LEU G 224 ? N LEU G 431 
AC2 1 2 N ILE G 143 ? N ILE G 350 O GLN G 198 ? O GLN G 405 
AC2 2 3 N LEU G 197 ? N LEU G 404 O LEU G 309 ? O LEU G 516 
AC2 3 4 O TYR G 307 ? O TYR G 514 N LEU G 247 ? N LEU G 454 
AC2 4 5 N VAL G 246 ? N VAL G 453 O TYR G 261 ? O TYR G 468 
AC2 5 6 N LEU G 262 ? N LEU G 469 O CYS G 271 ? O CYS G 478 
AC2 6 7 N ASP G 274 ? N ASP G 481 O VAL G 277 ? O VAL G 484 
AC3 1 2 N TYR G 172 ? N TYR G 379 O GLN G 180 ? O GLN G 387 
AC4 1 2 O ASP G 205 ? O ASP G 412 N THR G 208 ? N THR G 415 
AC5 1 2 O ILE H 13  ? O ILE H 13  N VAL H 5   ? N VAL H 5   
AC5 2 3 N PHE H 4   ? N PHE H 4   O LEU H 67  ? O LEU H 67  
AC5 3 4 O HIS H 68  ? O HIS H 68  N ILE H 44  ? N ILE H 44  
AC5 4 5 N PHE H 45  ? N PHE H 45  O LYS H 48  ? O LYS H 48  
# 
_pdbx_entry_details.entry_id                   9IML 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 246 ? ? -62.53  86.50   
2  1 GLU A 248 ? ? -73.83  37.91   
3  1 ASP A 250 ? ? 32.49   -111.73 
4  1 ASP A 251 ? ? -144.71 35.78   
5  1 SER A 252 ? ? 39.29   -78.03  
6  1 SER A 253 ? ? -62.31  7.51    
7  1 PRO A 273 ? ? -37.56  133.79  
8  1 ILE A 354 ? ? -126.16 -51.69  
9  1 ASN A 377 ? ? -141.74 43.78   
10 1 LYS A 420 ? ? 74.67   108.60  
11 1 ASP A 444 ? ? -166.66 68.71   
12 1 PRO A 445 ? ? -48.88  162.25  
13 1 ALA A 446 ? ? -108.13 59.49   
14 1 ASN A 470 ? ? -110.67 78.79   
15 1 ASP A 482 ? ? 48.19   -109.93 
16 1 ILE A 494 ? ? -109.28 -71.94  
17 1 ALA C 221 ? ? -144.18 12.86   
18 1 THR C 222 ? ? -69.78  33.70   
19 1 GLU C 286 ? ? -96.26  -111.25 
20 1 THR C 287 ? ? -143.39 -29.93  
21 1 ASN C 377 ? ? -141.55 42.43   
22 1 ALA C 381 ? ? -99.58  41.99   
23 1 ARG C 408 ? ? -93.72  49.90   
24 1 HIS C 451 ? ? -103.65 -65.08  
25 1 ASP C 459 ? ? -115.32 -162.87 
26 1 ASP C 482 ? ? 56.14   -110.06 
27 1 ILE C 494 ? ? -107.30 -78.86  
28 1 GLU E 248 ? ? -53.86  108.54  
29 1 LYS E 254 ? ? -141.87 20.62   
30 1 PRO E 273 ? ? -36.21  135.04  
31 1 ALA E 381 ? ? -102.57 61.86   
32 1 ARG E 408 ? ? -87.38  35.80   
33 1 ASP E 482 ? ? 47.39   -118.68 
34 1 ILE E 494 ? ? -110.93 -85.48  
35 1 GLN E 529 ? ? -38.40  132.14  
36 1 LEU F 71  ? ? -110.24 -148.91 
37 1 ALA G 221 ? ? -142.14 24.90   
38 1 THR G 222 ? ? -83.40  34.46   
39 1 GLU G 286 ? ? -102.71 -160.54 
40 1 ALA G 381 ? ? -104.06 48.69   
41 1 ARG G 408 ? ? -95.09  46.06   
42 1 PRO G 413 ? ? -64.02  74.22   
43 1 GLN G 414 ? ? 168.35  -31.36  
44 1 LYS G 443 ? ? -65.22  1.09    
45 1 ASP G 444 ? ? -170.94 96.85   
46 1 ASP G 482 ? ? 59.23   -96.57  
47 1 ARG G 487 ? ? -48.75  156.25  
48 1 ILE G 494 ? ? -120.38 -73.36  
49 1 TYR G 514 ? ? -121.81 -51.42  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A LYS 208 ? A LYS 1   
2   1 Y 1 A LYS 209 ? A LYS 2   
3   1 Y 1 A HIS 210 ? A HIS 3   
4   1 Y 1 A ASP 412 ? A ASP 205 
5   1 Y 1 A PRO 413 ? A PRO 206 
6   1 Y 1 A GLN 414 ? A GLN 207 
7   1 Y 1 A THR 415 ? A THR 208 
8   1 Y 1 A ASP 416 ? A ASP 209 
9   1 Y 1 A GLN 417 ? A GLN 210 
10  1 Y 1 A ASN 460 ? A ASN 253 
11  1 Y 1 A HIS 461 ? A HIS 254 
12  1 Y 1 A HIS 501 ? A HIS 294 
13  1 Y 1 A ASP 502 ? A ASP 295 
14  1 Y 1 A ASP 503 ? A ASP 296 
15  1 Y 1 A ASP 504 ? A ASP 297 
16  1 Y 1 A LEU 505 ? A LEU 298 
17  1 Y 1 A SER 506 ? A SER 299 
18  1 Y 1 A VAL 507 ? A VAL 300 
19  1 Y 1 A ARG 508 ? A ARG 301 
20  1 Y 1 A HIS 509 ? A HIS 302 
21  1 Y 1 A LYS 548 ? A LYS 341 
22  1 Y 1 A ARG 549 ? A ARG 342 
23  1 Y 1 A ILE 550 ? A ILE 343 
24  1 Y 1 A GLU 551 ? A GLU 344 
25  1 Y 1 A ALA 552 ? A ALA 345 
26  1 Y 1 A GLN 553 ? A GLN 346 
27  1 Y 1 A LYS 554 ? A LYS 347 
28  1 Y 1 A ARG 555 ? A ARG 348 
29  1 Y 1 A LYS 556 ? A LYS 349 
30  1 Y 1 A GLU 557 ? A GLU 350 
31  1 Y 1 A ARG 558 ? A ARG 351 
32  1 Y 1 A GLN 559 ? A GLN 352 
33  1 Y 1 A GLU 560 ? A GLU 353 
34  1 Y 1 C LYS 208 ? C LYS 1   
35  1 Y 1 C LYS 209 ? C LYS 2   
36  1 Y 1 C HIS 210 ? C HIS 3   
37  1 Y 1 C GLY 249 ? C GLY 42  
38  1 Y 1 C ASP 250 ? C ASP 43  
39  1 Y 1 C ASP 251 ? C ASP 44  
40  1 Y 1 C SER 252 ? C SER 45  
41  1 Y 1 C MET 410 ? C MET 203 
42  1 Y 1 C TYR 411 ? C TYR 204 
43  1 Y 1 C ASP 412 ? C ASP 205 
44  1 Y 1 C PRO 413 ? C PRO 206 
45  1 Y 1 C GLN 414 ? C GLN 207 
46  1 Y 1 C THR 415 ? C THR 208 
47  1 Y 1 C ASP 416 ? C ASP 209 
48  1 Y 1 C GLN 417 ? C GLN 210 
49  1 Y 1 C ASN 418 ? C ASN 211 
50  1 Y 1 C GLY 500 ? C GLY 293 
51  1 Y 1 C HIS 501 ? C HIS 294 
52  1 Y 1 C ASP 502 ? C ASP 295 
53  1 Y 1 C ASP 503 ? C ASP 296 
54  1 Y 1 C ASP 504 ? C ASP 297 
55  1 Y 1 C LEU 505 ? C LEU 298 
56  1 Y 1 C SER 506 ? C SER 299 
57  1 Y 1 C VAL 507 ? C VAL 300 
58  1 Y 1 C ARG 508 ? C ARG 301 
59  1 Y 1 C HIS 509 ? C HIS 302 
60  1 Y 1 C PRO 537 ? C PRO 330 
61  1 Y 1 C GLN 538 ? C GLN 331 
62  1 Y 1 C GLN 539 ? C GLN 332 
63  1 Y 1 C LEU 540 ? C LEU 333 
64  1 Y 1 C VAL 541 ? C VAL 334 
65  1 Y 1 C GLU 542 ? C GLU 335 
66  1 Y 1 C ARG 543 ? C ARG 336 
67  1 Y 1 C LEU 544 ? C LEU 337 
68  1 Y 1 C GLN 545 ? C GLN 338 
69  1 Y 1 C GLU 546 ? C GLU 339 
70  1 Y 1 C GLU 547 ? C GLU 340 
71  1 Y 1 C LYS 548 ? C LYS 341 
72  1 Y 1 C ARG 549 ? C ARG 342 
73  1 Y 1 C ILE 550 ? C ILE 343 
74  1 Y 1 C GLU 551 ? C GLU 344 
75  1 Y 1 C ALA 552 ? C ALA 345 
76  1 Y 1 C GLN 553 ? C GLN 346 
77  1 Y 1 C LYS 554 ? C LYS 347 
78  1 Y 1 C ARG 555 ? C ARG 348 
79  1 Y 1 C LYS 556 ? C LYS 349 
80  1 Y 1 C GLU 557 ? C GLU 350 
81  1 Y 1 C ARG 558 ? C ARG 351 
82  1 Y 1 C GLN 559 ? C GLN 352 
83  1 Y 1 C GLU 560 ? C GLU 353 
84  1 Y 1 E LYS 208 ? E LYS 1   
85  1 Y 1 E LYS 209 ? E LYS 2   
86  1 Y 1 E HIS 210 ? E HIS 3   
87  1 Y 1 E THR 211 ? E THR 4   
88  1 Y 1 E ASP 250 ? E ASP 43  
89  1 Y 1 E ASP 251 ? E ASP 44  
90  1 Y 1 E ASP 412 ? E ASP 205 
91  1 Y 1 E PRO 413 ? E PRO 206 
92  1 Y 1 E GLN 414 ? E GLN 207 
93  1 Y 1 E THR 415 ? E THR 208 
94  1 Y 1 E ASP 416 ? E ASP 209 
95  1 Y 1 E ASN 460 ? E ASN 253 
96  1 Y 1 E HIS 501 ? E HIS 294 
97  1 Y 1 E ASP 502 ? E ASP 295 
98  1 Y 1 E ASP 503 ? E ASP 296 
99  1 Y 1 E ASP 504 ? E ASP 297 
100 1 Y 1 E LEU 505 ? E LEU 298 
101 1 Y 1 E SER 506 ? E SER 299 
102 1 Y 1 E VAL 507 ? E VAL 300 
103 1 Y 1 E LYS 548 ? E LYS 341 
104 1 Y 1 E ARG 549 ? E ARG 342 
105 1 Y 1 E ILE 550 ? E ILE 343 
106 1 Y 1 E GLU 551 ? E GLU 344 
107 1 Y 1 E ALA 552 ? E ALA 345 
108 1 Y 1 E GLN 553 ? E GLN 346 
109 1 Y 1 E LYS 554 ? E LYS 347 
110 1 Y 1 E ARG 555 ? E ARG 348 
111 1 Y 1 E LYS 556 ? E LYS 349 
112 1 Y 1 E GLU 557 ? E GLU 350 
113 1 Y 1 E ARG 558 ? E ARG 351 
114 1 Y 1 E GLN 559 ? E GLN 352 
115 1 Y 1 E GLU 560 ? E GLU 353 
116 1 Y 1 G LYS 208 ? G LYS 1   
117 1 Y 1 G LYS 209 ? G LYS 2   
118 1 Y 1 G HIS 210 ? G HIS 3   
119 1 Y 1 G THR 211 ? G THR 4   
120 1 Y 1 G GLY 212 ? G GLY 5   
121 1 Y 1 G GLU 248 ? G GLU 41  
122 1 Y 1 G GLY 249 ? G GLY 42  
123 1 Y 1 G ASP 250 ? G ASP 43  
124 1 Y 1 G ASP 251 ? G ASP 44  
125 1 Y 1 G SER 252 ? G SER 45  
126 1 Y 1 G SER 270 ? G SER 63  
127 1 Y 1 G PRO 273 ? G PRO 66  
128 1 Y 1 G ASP 416 ? G ASP 209 
129 1 Y 1 G GLN 417 ? G GLN 210 
130 1 Y 1 G ASN 418 ? G ASN 211 
131 1 Y 1 G GLY 499 ? G GLY 292 
132 1 Y 1 G GLY 500 ? G GLY 293 
133 1 Y 1 G HIS 501 ? G HIS 294 
134 1 Y 1 G ASP 502 ? G ASP 295 
135 1 Y 1 G ASP 503 ? G ASP 296 
136 1 Y 1 G ASP 504 ? G ASP 297 
137 1 Y 1 G LEU 505 ? G LEU 298 
138 1 Y 1 G SER 506 ? G SER 299 
139 1 Y 1 G THR 532 ? G THR 325 
140 1 Y 1 G ASP 533 ? G ASP 326 
141 1 Y 1 G HIS 534 ? G HIS 327 
142 1 Y 1 G ASP 535 ? G ASP 328 
143 1 Y 1 G ILE 536 ? G ILE 329 
144 1 Y 1 G PRO 537 ? G PRO 330 
145 1 Y 1 G GLN 538 ? G GLN 331 
146 1 Y 1 G GLN 539 ? G GLN 332 
147 1 Y 1 G LEU 540 ? G LEU 333 
148 1 Y 1 G VAL 541 ? G VAL 334 
149 1 Y 1 G GLU 542 ? G GLU 335 
150 1 Y 1 G ARG 543 ? G ARG 336 
151 1 Y 1 G LEU 544 ? G LEU 337 
152 1 Y 1 G GLN 545 ? G GLN 338 
153 1 Y 1 G GLU 546 ? G GLU 339 
154 1 Y 1 G GLU 547 ? G GLU 340 
155 1 Y 1 G LYS 548 ? G LYS 341 
156 1 Y 1 G ARG 549 ? G ARG 342 
157 1 Y 1 G ILE 550 ? G ILE 343 
158 1 Y 1 G GLU 551 ? G GLU 344 
159 1 Y 1 G ALA 552 ? G ALA 345 
160 1 Y 1 G GLN 553 ? G GLN 346 
161 1 Y 1 G LYS 554 ? G LYS 347 
162 1 Y 1 G ARG 555 ? G ARG 348 
163 1 Y 1 G LYS 556 ? G LYS 349 
164 1 Y 1 G GLU 557 ? G GLU 350 
165 1 Y 1 G ARG 558 ? G ARG 351 
166 1 Y 1 G GLN 559 ? G GLN 352 
167 1 Y 1 G GLU 560 ? G GLU 353 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
XB7 C1   C N N 391 
XB7 C10  C N N 392 
XB7 C11  C N N 393 
XB7 C12  C N N 394 
XB7 C13  C Y N 395 
XB7 C14  C Y N 396 
XB7 C15  C Y N 397 
XB7 C16  C Y N 398 
XB7 C17  C Y N 399 
XB7 C18  C Y N 400 
XB7 C19  C Y N 401 
XB7 C2   C Y N 402 
XB7 C20  C N N 403 
XB7 C21  C Y N 404 
XB7 C22  C Y N 405 
XB7 C23  C Y N 406 
XB7 C24  C Y N 407 
XB7 C25  C Y N 408 
XB7 C26  C Y N 409 
XB7 C27  C Y N 410 
XB7 C28  C Y N 411 
XB7 C3   C Y N 412 
XB7 C4   C Y N 413 
XB7 C5   C Y N 414 
XB7 C6   C N N 415 
XB7 C7   C N N 416 
XB7 C8   C N N 417 
XB7 C9   C N N 418 
XB7 F1   F N N 419 
XB7 N1   N N N 420 
XB7 N2   N N N 421 
XB7 N3   N Y N 422 
XB7 N4   N Y N 423 
XB7 O1   O N N 424 
XB7 H1   H N N 425 
XB7 H2   H N N 426 
XB7 H3   H N N 427 
XB7 H4   H N N 428 
XB7 H5   H N N 429 
XB7 H6   H N N 430 
XB7 H7   H N N 431 
XB7 H8   H N N 432 
XB7 H9   H N N 433 
XB7 H10  H N N 434 
XB7 H11  H N N 435 
XB7 H12  H N N 436 
XB7 H13  H N N 437 
XB7 H14  H N N 438 
XB7 H15  H N N 439 
XB7 H16  H N N 440 
XB7 H17  H N N 441 
XB7 H18  H N N 442 
XB7 H19  H N N 443 
XB7 H20  H N N 444 
XB7 H21  H N N 445 
XB7 H22  H N N 446 
XB7 H23  H N N 447 
XB7 H24  H N N 448 
XB7 H25  H N N 449 
XB7 H26  H N N 450 
XB7 H27  H N N 451 
XB7 H28  H N N 452 
XB7 H29  H N N 453 
XB7 H30  H N N 454 
XB7 H32  H N N 455 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
XB7 C1  O1   sing N N 376 
XB7 O1  C2   sing N N 377 
XB7 C3  C2   doub Y N 378 
XB7 C3  C4   sing Y N 379 
XB7 C2  C28  sing Y N 380 
XB7 C4  C5   doub Y N 381 
XB7 C28 C27  doub Y N 382 
XB7 C5  C27  sing Y N 383 
XB7 C5  C6   sing N N 384 
XB7 C7  C6   sing N N 385 
XB7 C7  N1   sing N N 386 
XB7 C12 N1   sing N N 387 
XB7 C12 C11  sing N N 388 
XB7 N1  C8   sing N N 389 
XB7 C11 C10  sing N N 390 
XB7 C8  C9   sing N N 391 
XB7 F1  C24  sing N N 392 
XB7 C10 C9   sing N N 393 
XB7 C10 N2   sing N N 394 
XB7 C24 C23  doub Y N 395 
XB7 C24 C25  sing Y N 396 
XB7 C23 C22  sing Y N 397 
XB7 N3  C13  doub Y N 398 
XB7 N3  C14  sing Y N 399 
XB7 C25 C26  doub Y N 400 
XB7 N2  C13  sing N N 401 
XB7 C13 N4   sing Y N 402 
XB7 C15 C14  doub Y N 403 
XB7 C15 C16  sing Y N 404 
XB7 C22 C21  doub Y N 405 
XB7 C14 C19  sing Y N 406 
XB7 C26 C21  sing Y N 407 
XB7 C21 C20  sing N N 408 
XB7 C16 C17  doub Y N 409 
XB7 N4  C19  sing Y N 410 
XB7 N4  C20  sing N N 411 
XB7 C19 C18  doub Y N 412 
XB7 C17 C18  sing Y N 413 
XB7 C1  H1   sing N N 414 
XB7 C1  H2   sing N N 415 
XB7 C1  H3   sing N N 416 
XB7 C10 H4   sing N N 417 
XB7 C11 H5   sing N N 418 
XB7 C11 H6   sing N N 419 
XB7 C12 H7   sing N N 420 
XB7 C12 H8   sing N N 421 
XB7 C15 H9   sing N N 422 
XB7 C16 H10  sing N N 423 
XB7 C17 H11  sing N N 424 
XB7 C18 H12  sing N N 425 
XB7 C20 H13  sing N N 426 
XB7 C20 H14  sing N N 427 
XB7 C22 H15  sing N N 428 
XB7 C23 H16  sing N N 429 
XB7 C25 H17  sing N N 430 
XB7 C26 H18  sing N N 431 
XB7 C27 H19  sing N N 432 
XB7 C28 H20  sing N N 433 
XB7 C3  H21  sing N N 434 
XB7 C4  H22  sing N N 435 
XB7 C6  H23  sing N N 436 
XB7 C6  H24  sing N N 437 
XB7 C7  H25  sing N N 438 
XB7 C7  H26  sing N N 439 
XB7 C8  H27  sing N N 440 
XB7 C8  H28  sing N N 441 
XB7 C9  H29  sing N N 442 
XB7 C9  H30  sing N N 443 
XB7 N2  H32  sing N N 444 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32171220 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1NBF 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9IML 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009845 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000019 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011769 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009347 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
F 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . THR A 1 4   ? -11.222  -28.845 43.585  1.00 96.08  ? 211 THR A N   1 
ATOM   2     C CA  . THR A 1 4   ? -12.227  -28.384 42.590  1.00 86.64  ? 211 THR A CA  1 
ATOM   3     C C   . THR A 1 4   ? -13.462  -27.860 43.321  1.00 82.28  ? 211 THR A C   1 
ATOM   4     O O   . THR A 1 4   ? -14.091  -26.927 42.800  1.00 79.11  ? 211 THR A O   1 
ATOM   5     C CB  . THR A 1 4   ? -12.582  -29.510 41.616  1.00 79.87  ? 211 THR A CB  1 
ATOM   6     O OG1 . THR A 1 4   ? -13.891  -29.255 41.112  1.00 82.62  ? 211 THR A OG1 1 
ATOM   7     C CG2 . THR A 1 4   ? -12.528  -30.878 42.260  1.00 82.27  ? 211 THR A CG2 1 
ATOM   8     N N   . GLY A 1 5   ? -13.778  -28.430 44.483  1.00 81.34  ? 212 GLY A N   1 
ATOM   9     C CA  . GLY A 1 5   ? -14.993  -28.039 45.221  1.00 77.20  ? 212 GLY A CA  1 
ATOM   10    C C   . GLY A 1 5   ? -16.200  -28.790 44.709  1.00 82.49  ? 212 GLY A C   1 
ATOM   11    O O   . GLY A 1 5   ? -17.262  -28.694 45.343  1.00 64.11  ? 212 GLY A O   1 
ATOM   12    N N   . TYR A 1 6   ? -16.036  -29.515 43.601  1.00 79.00  ? 213 TYR A N   1 
ATOM   13    C CA  . TYR A 1 6   ? -17.149  -30.234 43.004  1.00 68.99  ? 213 TYR A CA  1 
ATOM   14    C C   . TYR A 1 6   ? -16.805  -31.713 42.983  1.00 68.20  ? 213 TYR A C   1 
ATOM   15    O O   . TYR A 1 6   ? -15.633  -32.084 42.871  1.00 68.57  ? 213 TYR A O   1 
ATOM   16    C CB  . TYR A 1 6   ? -17.454  -29.739 41.560  1.00 70.14  ? 213 TYR A CB  1 
ATOM   17    C CG  . TYR A 1 6   ? -17.790  -28.266 41.465  1.00 60.04  ? 213 TYR A CG  1 
ATOM   18    C CD1 . TYR A 1 6   ? -18.923  -27.756 42.077  1.00 63.28  ? 213 TYR A CD1 1 
ATOM   19    C CD2 . TYR A 1 6   ? -16.965  -27.387 40.780  1.00 65.93  ? 213 TYR A CD2 1 
ATOM   20    C CE1 . TYR A 1 6   ? -19.229  -26.411 42.019  1.00 66.47  ? 213 TYR A CE1 1 
ATOM   21    C CE2 . TYR A 1 6   ? -17.263  -26.030 40.708  1.00 65.99  ? 213 TYR A CE2 1 
ATOM   22    C CZ  . TYR A 1 6   ? -18.399  -25.547 41.335  1.00 65.39  ? 213 TYR A CZ  1 
ATOM   23    O OH  . TYR A 1 6   ? -18.717  -24.205 41.280  1.00 63.68  ? 213 TYR A OH  1 
ATOM   24    N N   . VAL A 1 7   ? -17.841  -32.553 43.089  1.00 70.04  ? 214 VAL A N   1 
ATOM   25    C CA  . VAL A 1 7   ? -17.687  -34.001 43.094  1.00 63.70  ? 214 VAL A CA  1 
ATOM   26    C C   . VAL A 1 7   ? -17.982  -34.530 41.700  1.00 65.16  ? 214 VAL A C   1 
ATOM   27    O O   . VAL A 1 7   ? -18.783  -33.963 40.943  1.00 67.83  ? 214 VAL A O   1 
ATOM   28    C CB  . VAL A 1 7   ? -18.603  -34.664 44.146  1.00 66.96  ? 214 VAL A CB  1 
ATOM   29    N N   . GLY A 1 8   ? -17.323  -35.627 41.359  1.00 62.36  ? 215 GLY A N   1 
ATOM   30    C CA  . GLY A 1 8   ? -17.544  -36.318 40.111  1.00 60.58  ? 215 GLY A CA  1 
ATOM   31    C C   . GLY A 1 8   ? -18.604  -37.379 40.254  1.00 63.82  ? 215 GLY A C   1 
ATOM   32    O O   . GLY A 1 8   ? -19.352  -37.411 41.232  1.00 67.81  ? 215 GLY A O   1 
ATOM   33    N N   . LEU A 1 9   ? -18.683  -38.237 39.233  1.00 66.77  ? 216 LEU A N   1 
ATOM   34    C CA  . LEU A 1 9   ? -19.724  -39.287 39.176  1.00 59.73  ? 216 LEU A CA  1 
ATOM   35    C C   . LEU A 1 9   ? -19.089  -40.588 38.698  1.00 68.06  ? 216 LEU A C   1 
ATOM   36    O O   . LEU A 1 9   ? -18.360  -40.555 37.719  1.00 67.54  ? 216 LEU A O   1 
ATOM   37    C CB  . LEU A 1 9   ? -20.781  -38.840 38.169  1.00 67.18  ? 216 LEU A CB  1 
ATOM   38    C CG  . LEU A 1 9   ? -22.027  -38.172 38.742  1.00 71.33  ? 216 LEU A CG  1 
ATOM   39    C CD1 . LEU A 1 9   ? -22.652  -37.250 37.711  1.00 61.13  ? 216 LEU A CD1 1 
ATOM   40    C CD2 . LEU A 1 9   ? -23.038  -39.210 39.196  1.00 64.16  ? 216 LEU A CD2 1 
ATOM   41    N N   . LYS A 1 10  ? -19.423  -41.707 39.323  1.00 70.06  ? 217 LYS A N   1 
ATOM   42    C CA  . LYS A 1 10  ? -18.799  -43.004 38.994  1.00 57.33  ? 217 LYS A CA  1 
ATOM   43    C C   . LYS A 1 10  ? -19.249  -43.461 37.612  1.00 55.65  ? 217 LYS A C   1 
ATOM   44    O O   . LYS A 1 10  ? -20.387  -43.171 37.231  1.00 61.21  ? 217 LYS A O   1 
ATOM   45    C CB  . LYS A 1 10  ? -19.157  -44.053 40.048  1.00 51.21  ? 217 LYS A CB  1 
ATOM   46    N N   . ASN A 1 11  ? -18.363  -44.137 36.891  1.00 64.76  ? 218 ASN A N   1 
ATOM   47    C CA  . ASN A 1 11  ? -18.727  -44.729 35.583  1.00 68.03  ? 218 ASN A CA  1 
ATOM   48    C C   . ASN A 1 11  ? -19.117  -46.177 35.856  1.00 69.54  ? 218 ASN A C   1 
ATOM   49    O O   . ASN A 1 11  ? -18.243  -46.952 36.283  1.00 73.61  ? 218 ASN A O   1 
ATOM   50    C CB  . ASN A 1 11  ? -17.572  -44.660 34.587  1.00 66.95  ? 218 ASN A CB  1 
ATOM   51    C CG  . ASN A 1 11  ? -17.850  -45.359 33.278  1.00 68.09  ? 218 ASN A CG  1 
ATOM   52    O OD1 . ASN A 1 11  ? -18.934  -45.230 32.719  1.00 67.04  ? 218 ASN A OD1 1 
ATOM   53    N ND2 . ASN A 1 11  ? -16.871  -46.094 32.783  1.00 56.70  ? 218 ASN A ND2 1 
ATOM   54    N N   . GLN A 1 12  ? -20.385  -46.509 35.651  1.00 62.82  ? 219 GLN A N   1 
ATOM   55    C CA  . GLN A 1 12  ? -20.831  -47.907 35.830  1.00 66.97  ? 219 GLN A CA  1 
ATOM   56    C C   . GLN A 1 12  ? -20.161  -48.773 34.766  1.00 71.19  ? 219 GLN A C   1 
ATOM   57    O O   . GLN A 1 12  ? -19.986  -49.973 35.017  1.00 74.49  ? 219 GLN A O   1 
ATOM   58    C CB  . GLN A 1 12  ? -22.352  -47.984 35.736  1.00 64.70  ? 219 GLN A CB  1 
ATOM   59    N N   . GLY A 1 13  ? -19.800  -48.176 33.632  1.00 71.15  ? 220 GLY A N   1 
ATOM   60    C CA  . GLY A 1 13  ? -19.146  -48.921 32.544  1.00 66.02  ? 220 GLY A CA  1 
ATOM   61    C C   . GLY A 1 13  ? -19.090  -48.101 31.278  1.00 67.43  ? 220 GLY A C   1 
ATOM   62    O O   . GLY A 1 13  ? -17.992  -47.953 30.725  1.00 64.55  ? 220 GLY A O   1 
ATOM   63    N N   . ALA A 1 14  ? -20.236  -47.589 30.839  1.00 30.00  ? 221 ALA A N   1 
ATOM   64    C CA  . ALA A 1 14  ? -20.282  -46.731 29.638  1.00 30.00  ? 221 ALA A CA  1 
ATOM   65    C C   . ALA A 1 14  ? -21.112  -45.483 29.924  1.00 30.00  ? 221 ALA A C   1 
ATOM   66    O O   . ALA A 1 14  ? -21.380  -44.761 28.973  1.00 30.00  ? 221 ALA A O   1 
ATOM   67    C CB  . ALA A 1 14  ? -20.859  -47.505 28.494  1.00 30.00  ? 221 ALA A CB  1 
ATOM   68    N N   . THR A 1 15  ? -21.444  -45.227 31.186  1.00 65.92  ? 222 THR A N   1 
ATOM   69    C CA  . THR A 1 15  ? -22.310  -44.085 31.563  1.00 62.95  ? 222 THR A CA  1 
ATOM   70    C C   . THR A 1 15  ? -21.568  -42.759 31.411  1.00 61.34  ? 222 THR A C   1 
ATOM   71    O O   . THR A 1 15  ? -22.026  -41.790 32.009  1.00 65.16  ? 222 THR A O   1 
ATOM   72    C CB  . THR A 1 15  ? -22.845  -44.284 32.985  1.00 69.36  ? 222 THR A CB  1 
ATOM   73    O OG1 . THR A 1 15  ? -21.751  -44.283 33.902  1.00 67.48  ? 222 THR A OG1 1 
ATOM   74    C CG2 . THR A 1 15  ? -23.633  -45.566 33.127  1.00 60.09  ? 222 THR A CG2 1 
ATOM   75    N N   . CYS A 1 16  ? -20.484  -42.713 30.638  1.00 63.97  ? 223 CYS A N   1 
ATOM   76    C CA  . CYS A 1 16  ? -19.789  -41.430 30.366  1.00 62.41  ? 223 CYS A CA  1 
ATOM   77    C C   . CYS A 1 16  ? -20.823  -40.418 29.879  1.00 61.92  ? 223 CYS A C   1 
ATOM   78    O O   . CYS A 1 16  ? -20.815  -39.297 30.389  1.00 57.23  ? 223 CYS A O   1 
ATOM   79    C CB  . CYS A 1 16  ? -18.723  -41.594 29.289  1.00 55.68  ? 223 CYS A CB  1 
ATOM   80    S SG  . CYS A 1 16  ? -18.304  -43.303 28.876  1.00 68.98  ? 223 CYS A SG  1 
ATOM   81    N N   . TYR A 1 17  ? -21.681  -40.822 28.940  1.00 56.69  ? 224 TYR A N   1 
ATOM   82    C CA  . TYR A 1 17  ? -22.727  -39.932 28.374  1.00 59.93  ? 224 TYR A CA  1 
ATOM   83    C C   . TYR A 1 17  ? -23.597  -39.375 29.492  1.00 58.50  ? 224 TYR A C   1 
ATOM   84    O O   . TYR A 1 17  ? -23.787  -38.161 29.558  1.00 54.80  ? 224 TYR A O   1 
ATOM   85    C CB  . TYR A 1 17  ? -23.560  -40.676 27.322  1.00 53.10  ? 224 TYR A CB  1 
ATOM   86    C CG  . TYR A 1 17  ? -24.324  -41.892 27.775  1.00 59.44  ? 224 TYR A CG  1 
ATOM   87    C CD1 . TYR A 1 17  ? -23.710  -43.125 27.855  1.00 64.94  ? 224 TYR A CD1 1 
ATOM   88    C CD2 . TYR A 1 17  ? -25.670  -41.821 28.087  1.00 59.88  ? 224 TYR A CD2 1 
ATOM   89    C CE1 . TYR A 1 17  ? -24.398  -44.249 28.274  1.00 66.91  ? 224 TYR A CE1 1 
ATOM   90    C CE2 . TYR A 1 17  ? -26.374  -42.932 28.516  1.00 62.16  ? 224 TYR A CE2 1 
ATOM   91    C CZ  . TYR A 1 17  ? -25.733  -44.152 28.606  1.00 68.32  ? 224 TYR A CZ  1 
ATOM   92    O OH  . TYR A 1 17  ? -26.398  -45.270 29.007  1.00 68.84  ? 224 TYR A OH  1 
ATOM   93    N N   . MET A 1 18  ? -24.090  -40.246 30.370  1.00 58.25  ? 225 MET A N   1 
ATOM   94    C CA  . MET A 1 18  ? -25.040  -39.830 31.427  1.00 57.44  ? 225 MET A CA  1 
ATOM   95    C C   . MET A 1 18  ? -24.344  -38.896 32.396  1.00 61.05  ? 225 MET A C   1 
ATOM   96    O O   . MET A 1 18  ? -24.847  -37.820 32.586  1.00 58.16  ? 225 MET A O   1 
ATOM   97    C CB  . MET A 1 18  ? -25.542  -41.046 32.200  1.00 58.26  ? 225 MET A CB  1 
ATOM   98    C CG  . MET A 1 18  ? -26.798  -40.787 32.983  1.00 55.90  ? 225 MET A CG  1 
ATOM   99    S SD  . MET A 1 18  ? -27.455  -42.339 33.589  1.00 72.97  ? 225 MET A SD  1 
ATOM   100   C CE  . MET A 1 18  ? -27.495  -43.261 32.054  1.00 66.73  ? 225 MET A CE  1 
ATOM   101   N N   . ASN A 1 19  ? -23.227  -39.325 32.965  1.00 61.15  ? 226 ASN A N   1 
ATOM   102   C CA  . ASN A 1 19  ? -22.469  -38.493 33.928  1.00 55.79  ? 226 ASN A CA  1 
ATOM   103   C C   . ASN A 1 19  ? -22.248  -37.110 33.318  1.00 52.75  ? 226 ASN A C   1 
ATOM   104   O O   . ASN A 1 19  ? -22.501  -36.142 34.007  1.00 55.07  ? 226 ASN A O   1 
ATOM   105   C CB  . ASN A 1 19  ? -21.171  -39.185 34.342  1.00 61.97  ? 226 ASN A CB  1 
ATOM   106   C CG  . ASN A 1 19  ? -21.378  -40.585 34.870  1.00 66.18  ? 226 ASN A CG  1 
ATOM   107   O OD1 . ASN A 1 19  ? -22.437  -40.904 35.397  1.00 69.51  ? 226 ASN A OD1 1 
ATOM   108   N ND2 . ASN A 1 19  ? -20.373  -41.430 34.725  1.00 66.96  ? 226 ASN A ND2 1 
ATOM   109   N N   . SER A 1 20  ? -21.852  -37.040 32.052  1.00 53.21  ? 227 SER A N   1 
ATOM   110   C CA  . SER A 1 20  ? -21.571  -35.743 31.384  1.00 56.59  ? 227 SER A CA  1 
ATOM   111   C C   . SER A 1 20  ? -22.840  -34.894 31.280  1.00 56.95  ? 227 SER A C   1 
ATOM   112   O O   . SER A 1 20  ? -22.734  -33.678 31.430  1.00 50.90  ? 227 SER A O   1 
ATOM   113   C CB  . SER A 1 20  ? -20.946  -35.973 30.046  1.00 57.56  ? 227 SER A CB  1 
ATOM   114   O OG  . SER A 1 20  ? -19.687  -36.605 30.185  1.00 68.00  ? 227 SER A OG  1 
ATOM   115   N N   . LEU A 1 21  ? -23.992  -35.516 31.036  1.00 52.25  ? 228 LEU A N   1 
ATOM   116   C CA  . LEU A 1 21  ? -25.271  -34.765 31.004  1.00 49.98  ? 228 LEU A CA  1 
ATOM   117   C C   . LEU A 1 21  ? -25.741  -34.498 32.428  1.00 51.78  ? 228 LEU A C   1 
ATOM   118   O O   . LEU A 1 21  ? -26.196  -33.400 32.688  1.00 49.50  ? 228 LEU A O   1 
ATOM   119   C CB  . LEU A 1 21  ? -26.333  -35.573 30.264  1.00 49.39  ? 228 LEU A CB  1 
ATOM   120   C CG  . LEU A 1 21  ? -27.656  -34.840 30.072  1.00 46.72  ? 228 LEU A CG  1 
ATOM   121   C CD1 . LEU A 1 21  ? -27.564  -33.861 28.918  1.00 50.34  ? 228 LEU A CD1 1 
ATOM   122   C CD2 . LEU A 1 21  ? -28.803  -35.810 29.877  1.00 53.34  ? 228 LEU A CD2 1 
ATOM   123   N N   . LEU A 1 22  ? -25.681  -35.505 33.288  1.00 49.76  ? 229 LEU A N   1 
ATOM   124   C CA  . LEU A 1 22  ? -26.113  -35.339 34.691  1.00 48.42  ? 229 LEU A CA  1 
ATOM   125   C C   . LEU A 1 22  ? -25.355  -34.157 35.267  1.00 50.29  ? 229 LEU A C   1 
ATOM   126   O O   . LEU A 1 22  ? -25.980  -33.388 35.973  1.00 53.10  ? 229 LEU A O   1 
ATOM   127   C CB  . LEU A 1 22  ? -25.800  -36.608 35.481  1.00 49.95  ? 229 LEU A CB  1 
ATOM   128   C CG  . LEU A 1 22  ? -26.793  -37.753 35.339  1.00 55.37  ? 229 LEU A CG  1 
ATOM   129   C CD1 . LEU A 1 22  ? -26.407  -38.898 36.259  1.00 44.94  ? 229 LEU A CD1 1 
ATOM   130   C CD2 . LEU A 1 22  ? -28.201  -37.276 35.633  1.00 49.04  ? 229 LEU A CD2 1 
ATOM   131   N N   . GLN A 1 23  ? -24.067  -34.020 34.952  1.00 47.15  ? 230 GLN A N   1 
ATOM   132   C CA  . GLN A 1 23  ? -23.387  -32.837 35.445  1.00 53.39  ? 230 GLN A CA  1 
ATOM   133   C C   . GLN A 1 23  ? -23.972  -31.589 34.809  1.00 48.50  ? 230 GLN A C   1 
ATOM   134   O O   . GLN A 1 23  ? -24.193  -30.579 35.488  1.00 51.88  ? 230 GLN A O   1 
ATOM   135   C CB  . GLN A 1 23  ? -21.883  -32.937 35.181  1.00 53.55  ? 230 GLN A CB  1 
ATOM   136   C CG  . GLN A 1 23  ? -21.203  -34.090 35.908  1.00 56.06  ? 230 GLN A CG  1 
ATOM   137   C CD  . GLN A 1 23  ? -20.866  -33.779 37.370  1.00 61.40  ? 230 GLN A CD  1 
ATOM   138   O OE1 . GLN A 1 23  ? -21.281  -32.749 37.922  1.00 53.24  ? 230 GLN A OE1 1 
ATOM   139   N NE2 . GLN A 1 23  ? -20.110  -34.679 38.002  1.00 58.39  ? 230 GLN A NE2 1 
ATOM   140   N N   . THR A 1 24  ? -24.193  -31.624 33.503  1.00 45.91  ? 231 THR A N   1 
ATOM   141   C CA  . THR A 1 24  ? -24.709  -30.432 32.785  1.00 48.11  ? 231 THR A CA  1 
ATOM   142   C C   . THR A 1 24  ? -26.066  -30.039 33.376  1.00 48.57  ? 231 THR A C   1 
ATOM   143   O O   . THR A 1 24  ? -26.254  -28.855 33.666  1.00 46.71  ? 231 THR A O   1 
ATOM   144   C CB  . THR A 1 24  ? -24.751  -30.683 31.273  1.00 48.37  ? 231 THR A CB  1 
ATOM   145   O OG1 . THR A 1 24  ? -23.458  -31.106 30.849  1.00 49.20  ? 231 THR A OG1 1 
ATOM   146   C CG2 . THR A 1 24  ? -25.169  -29.466 30.481  1.00 38.81  ? 231 THR A CG2 1 
ATOM   147   N N   . LEU A 1 25  ? -26.967  -31.005 33.544  1.00 46.09  ? 232 LEU A N   1 
ATOM   148   C CA  . LEU A 1 25  ? -28.310  -30.681 34.065  1.00 46.84  ? 232 LEU A CA  1 
ATOM   149   C C   . LEU A 1 25  ? -28.211  -30.320 35.551  1.00 55.67  ? 232 LEU A C   1 
ATOM   150   O O   . LEU A 1 25  ? -29.037  -29.523 36.004  1.00 57.50  ? 232 LEU A O   1 
ATOM   151   C CB  . LEU A 1 25  ? -29.217  -31.881 33.789  1.00 49.98  ? 232 LEU A CB  1 
ATOM   152   C CG  . LEU A 1 25  ? -29.553  -32.120 32.320  1.00 45.46  ? 232 LEU A CG  1 
ATOM   153   C CD1 . LEU A 1 25  ? -30.701  -33.099 32.192  1.00 44.53  ? 232 LEU A CD1 1 
ATOM   154   C CD2 . LEU A 1 25  ? -29.888  -30.819 31.611  1.00 40.80  ? 232 LEU A CD2 1 
ATOM   155   N N   . PHE A 1 26  ? -27.231  -30.862 36.277  1.00 55.52  ? 233 PHE A N   1 
ATOM   156   C CA  . PHE A 1 26  ? -27.033  -30.494 37.675  1.00 55.57  ? 233 PHE A CA  1 
ATOM   157   C C   . PHE A 1 26  ? -26.637  -29.033 37.813  1.00 52.27  ? 233 PHE A C   1 
ATOM   158   O O   . PHE A 1 26  ? -27.214  -28.300 38.619  1.00 54.46  ? 233 PHE A O   1 
ATOM   159   C CB  . PHE A 1 26  ? -25.983  -31.397 38.309  1.00 59.35  ? 233 PHE A CB  1 
ATOM   160   C CG  . PHE A 1 26  ? -25.619  -31.015 39.716  1.00 64.53  ? 233 PHE A CG  1 
ATOM   161   C CD1 . PHE A 1 26  ? -26.413  -31.421 40.791  1.00 68.64  ? 233 PHE A CD1 1 
ATOM   162   C CD2 . PHE A 1 26  ? -24.462  -30.278 39.975  1.00 60.02  ? 233 PHE A CD2 1 
ATOM   163   C CE1 . PHE A 1 26  ? -26.072  -31.078 42.107  1.00 67.71  ? 233 PHE A CE1 1 
ATOM   164   C CE2 . PHE A 1 26  ? -24.110  -29.937 41.277  1.00 63.34  ? 233 PHE A CE2 1 
ATOM   165   C CZ  . PHE A 1 26  ? -24.920  -30.332 42.347  1.00 68.80  ? 233 PHE A CZ  1 
ATOM   166   N N   . PHE A 1 27  ? -25.672  -28.592 37.020  1.00 50.64  ? 234 PHE A N   1 
ATOM   167   C CA  . PHE A 1 27  ? -25.173  -27.201 37.170  1.00 52.48  ? 234 PHE A CA  1 
ATOM   168   C C   . PHE A 1 27  ? -26.162  -26.217 36.551  1.00 51.23  ? 234 PHE A C   1 
ATOM   169   O O   . PHE A 1 27  ? -25.937  -25.018 36.708  1.00 58.85  ? 234 PHE A O   1 
ATOM   170   C CB  . PHE A 1 27  ? -23.744  -27.082 36.646  1.00 52.45  ? 234 PHE A CB  1 
ATOM   171   C CG  . PHE A 1 27  ? -22.723  -27.717 37.547  1.00 53.29  ? 234 PHE A CG  1 
ATOM   172   C CD1 . PHE A 1 27  ? -22.513  -27.229 38.824  1.00 55.91  ? 234 PHE A CD1 1 
ATOM   173   C CD2 . PHE A 1 27  ? -21.992  -28.811 37.126  1.00 52.22  ? 234 PHE A CD2 1 
ATOM   174   C CE1 . PHE A 1 27  ? -21.577  -27.815 39.656  1.00 56.02  ? 234 PHE A CE1 1 
ATOM   175   C CE2 . PHE A 1 27  ? -21.063  -29.400 37.964  1.00 56.51  ? 234 PHE A CE2 1 
ATOM   176   C CZ  . PHE A 1 27  ? -20.855  -28.901 39.226  1.00 55.14  ? 234 PHE A CZ  1 
ATOM   177   N N   . THR A 1 28  ? -27.179  -26.693 35.836  1.00 53.17  ? 235 THR A N   1 
ATOM   178   C CA  . THR A 1 28  ? -28.274  -25.799 35.389  1.00 42.95  ? 235 THR A CA  1 
ATOM   179   C C   . THR A 1 28  ? -29.057  -25.625 36.686  1.00 52.70  ? 235 THR A C   1 
ATOM   180   O O   . THR A 1 28  ? -30.037  -26.346 36.877  1.00 51.86  ? 235 THR A O   1 
ATOM   181   C CB  . THR A 1 28  ? -29.006  -26.395 34.183  1.00 40.62  ? 235 THR A CB  1 
ATOM   182   O OG1 . THR A 1 28  ? -28.044  -26.734 33.188  1.00 42.38  ? 235 THR A OG1 1 
ATOM   183   C CG2 . THR A 1 28  ? -30.028  -25.452 33.588  1.00 44.91  ? 235 THR A CG2 1 
ATOM   184   N N   . ASN A 1 29  ? -28.598  -24.740 37.564  1.00 52.84  ? 236 ASN A N   1 
ATOM   185   C CA  . ASN A 1 29  ? -29.147  -24.608 38.936  1.00 47.30  ? 236 ASN A CA  1 
ATOM   186   C C   . ASN A 1 29  ? -30.671  -24.493 38.965  1.00 50.87  ? 236 ASN A C   1 
ATOM   187   O O   . ASN A 1 29  ? -31.267  -25.172 39.798  1.00 54.17  ? 236 ASN A O   1 
ATOM   188   C CB  . ASN A 1 29  ? -28.419  -23.474 39.658  1.00 50.60  ? 236 ASN A CB  1 
ATOM   189   C CG  . ASN A 1 29  ? -26.954  -23.751 39.906  1.00 49.59  ? 236 ASN A CG  1 
ATOM   190   O OD1 . ASN A 1 29  ? -26.511  -24.891 39.842  1.00 46.44  ? 236 ASN A OD1 1 
ATOM   191   N ND2 . ASN A 1 29  ? -26.198  -22.710 40.206  1.00 53.32  ? 236 ASN A ND2 1 
ATOM   192   N N   . GLN A 1 30  ? -31.270  -23.643 38.136  1.00 51.86  ? 237 GLN A N   1 
ATOM   193   C CA  . GLN A 1 30  ? -32.717  -23.458 38.187  1.00 51.72  ? 237 GLN A CA  1 
ATOM   194   C C   . GLN A 1 30  ? -33.456  -24.770 37.949  1.00 54.61  ? 237 GLN A C   1 
ATOM   195   O O   . GLN A 1 30  ? -34.501  -25.026 38.560  1.00 49.62  ? 237 GLN A O   1 
ATOM   196   C CB  . GLN A 1 30  ? -33.134  -22.419 37.163  1.00 42.81  ? 237 GLN A CB  1 
ATOM   197   C CG  . GLN A 1 30  ? -34.556  -22.028 37.295  1.00 51.75  ? 237 GLN A CG  1 
ATOM   198   C CD  . GLN A 1 30  ? -34.805  -20.643 36.746  1.00 59.40  ? 237 GLN A CD  1 
ATOM   199   O OE1 . GLN A 1 30  ? -33.923  -20.048 36.136  1.00 65.11  ? 237 GLN A OE1 1 
ATOM   200   N NE2 . GLN A 1 30  ? -36.003  -20.122 36.956  1.00 54.56  ? 237 GLN A NE2 1 
ATOM   201   N N   . LEU A 1 31  ? -32.920  -25.623 37.075  1.00 52.87  ? 238 LEU A N   1 
ATOM   202   C CA  . LEU A 1 31  ? -33.510  -26.939 36.892  1.00 50.70  ? 238 LEU A CA  1 
ATOM   203   C C   . LEU A 1 31  ? -33.369  -27.760 38.159  1.00 54.44  ? 238 LEU A C   1 
ATOM   204   O O   . LEU A 1 31  ? -34.326  -28.402 38.606  1.00 58.38  ? 238 LEU A O   1 
ATOM   205   C CB  . LEU A 1 31  ? -32.850  -27.646 35.709  1.00 45.56  ? 238 LEU A CB  1 
ATOM   206   C CG  . LEU A 1 31  ? -33.322  -29.047 35.381  1.00 42.36  ? 238 LEU A CG  1 
ATOM   207   C CD1 . LEU A 1 31  ? -34.806  -28.982 35.088  1.00 55.98  ? 238 LEU A CD1 1 
ATOM   208   C CD2 . LEU A 1 31  ? -32.558  -29.573 34.173  1.00 46.12  ? 238 LEU A CD2 1 
ATOM   209   N N   . ARG A 1 32  ? -32.182  -27.731 38.764  1.00 48.50  ? 239 ARG A N   1 
ATOM   210   C CA  . ARG A 1 32  ? -31.919  -28.602 39.899  1.00 55.43  ? 239 ARG A CA  1 
ATOM   211   C C   . ARG A 1 32  ? -32.821  -28.239 41.065  1.00 61.76  ? 239 ARG A C   1 
ATOM   212   O O   . ARG A 1 32  ? -33.400  -29.118 41.718  1.00 58.71  ? 239 ARG A O   1 
ATOM   213   C CB  . ARG A 1 32  ? -30.447  -28.517 40.302  1.00 55.48  ? 239 ARG A CB  1 
ATOM   214   C CG  . ARG A 1 32  ? -30.039  -29.586 41.285  1.00 54.57  ? 239 ARG A CG  1 
ATOM   215   C CD  . ARG A 1 32  ? -29.033  -29.032 42.240  1.00 63.30  ? 239 ARG A CD  1 
ATOM   216   N NE  . ARG A 1 32  ? -27.843  -28.534 41.559  1.00 62.50  ? 239 ARG A NE  1 
ATOM   217   C CZ  . ARG A 1 32  ? -26.935  -27.749 42.124  1.00 60.32  ? 239 ARG A CZ  1 
ATOM   218   N NH1 . ARG A 1 32  ? -27.089  -27.357 43.379  1.00 61.81  ? 239 ARG A NH1 1 
ATOM   219   N NH2 . ARG A 1 32  ? -25.877  -27.348 41.430  1.00 55.01  ? 239 ARG A NH2 1 
ATOM   220   N N   . LYS A 1 33  ? -32.952  -26.936 41.343  1.00 60.29  ? 240 LYS A N   1 
ATOM   221   C CA  . LYS A 1 33  ? -33.927  -26.509 42.332  1.00 63.37  ? 240 LYS A CA  1 
ATOM   222   C C   . LYS A 1 33  ? -35.300  -27.068 41.975  1.00 61.77  ? 240 LYS A C   1 
ATOM   223   O O   . LYS A 1 33  ? -35.988  -27.630 42.831  1.00 65.96  ? 240 LYS A O   1 
ATOM   224   C CB  . LYS A 1 33  ? -33.947  -24.977 42.447  1.00 55.55  ? 240 LYS A CB  1 
ATOM   225   N N   . ALA A 1 34  ? -35.674  -27.006 40.696  1.00 60.20  ? 241 ALA A N   1 
ATOM   226   C CA  . ALA A 1 34  ? -36.985  -27.503 40.283  1.00 59.44  ? 241 ALA A CA  1 
ATOM   227   C C   . ALA A 1 34  ? -37.111  -29.008 40.489  1.00 57.26  ? 241 ALA A C   1 
ATOM   228   O O   . ALA A 1 34  ? -38.180  -29.495 40.867  1.00 59.04  ? 241 ALA A O   1 
ATOM   229   C CB  . ALA A 1 34  ? -37.258  -27.147 38.824  1.00 52.22  ? 241 ALA A CB  1 
ATOM   230   N N   . VAL A 1 35  ? -36.051  -29.770 40.232  1.00 57.46  ? 242 VAL A N   1 
ATOM   231   C CA  . VAL A 1 35  ? -36.149  -31.209 40.461  1.00 57.90  ? 242 VAL A CA  1 
ATOM   232   C C   . VAL A 1 35  ? -36.323  -31.488 41.952  1.00 61.95  ? 242 VAL A C   1 
ATOM   233   O O   . VAL A 1 35  ? -37.126  -32.341 42.359  1.00 57.25  ? 242 VAL A O   1 
ATOM   234   C CB  . VAL A 1 35  ? -34.923  -31.933 39.870  1.00 55.43  ? 242 VAL A CB  1 
ATOM   235   C CG1 . VAL A 1 35  ? -34.847  -33.362 40.369  1.00 56.89  ? 242 VAL A CG1 1 
ATOM   236   C CG2 . VAL A 1 35  ? -34.958  -31.896 38.349  1.00 49.24  ? 242 VAL A CG2 1 
ATOM   237   N N   . TYR A 1 36  ? -35.606  -30.736 42.790  1.00 62.02  ? 243 TYR A N   1 
ATOM   238   C CA  . TYR A 1 36  ? -35.734  -30.881 44.236  1.00 63.95  ? 243 TYR A CA  1 
ATOM   239   C C   . TYR A 1 36  ? -37.171  -30.660 44.719  1.00 62.26  ? 243 TYR A C   1 
ATOM   240   O O   . TYR A 1 36  ? -37.566  -31.192 45.760  1.00 67.20  ? 243 TYR A O   1 
ATOM   241   C CB  . TYR A 1 36  ? -34.790  -29.895 44.930  1.00 65.28  ? 243 TYR A CB  1 
ATOM   242   C CG  . TYR A 1 36  ? -33.318  -30.275 44.952  1.00 62.94  ? 243 TYR A CG  1 
ATOM   243   C CD1 . TYR A 1 36  ? -32.916  -31.602 45.065  1.00 59.65  ? 243 TYR A CD1 1 
ATOM   244   C CD2 . TYR A 1 36  ? -32.332  -29.289 44.875  1.00 60.78  ? 243 TYR A CD2 1 
ATOM   245   C CE1 . TYR A 1 36  ? -31.574  -31.935 45.096  1.00 61.91  ? 243 TYR A CE1 1 
ATOM   246   C CE2 . TYR A 1 36  ? -30.994  -29.611 44.908  1.00 57.79  ? 243 TYR A CE2 1 
ATOM   247   C CZ  . TYR A 1 36  ? -30.615  -30.935 45.019  1.00 63.35  ? 243 TYR A CZ  1 
ATOM   248   O OH  . TYR A 1 36  ? -29.272  -31.264 45.061  1.00 60.75  ? 243 TYR A OH  1 
ATOM   249   N N   . MET A 1 37  ? -37.893  -29.757 44.065  1.00 62.44  ? 244 MET A N   1 
ATOM   250   C CA  . MET A 1 37  ? -39.243  -29.379 44.554  1.00 63.48  ? 244 MET A CA  1 
ATOM   251   C C   . MET A 1 37  ? -40.326  -30.229 43.888  1.00 62.48  ? 244 MET A C   1 
ATOM   252   O O   . MET A 1 37  ? -41.490  -29.802 43.884  1.00 66.64  ? 244 MET A O   1 
ATOM   253   C CB  . MET A 1 37  ? -39.495  -27.898 44.264  1.00 58.11  ? 244 MET A CB  1 
ATOM   254   C CG  . MET A 1 37  ? -38.653  -26.964 45.089  1.00 60.07  ? 244 MET A CG  1 
ATOM   255   S SD  . MET A 1 37  ? -39.147  -25.264 44.758  1.00 91.23  ? 244 MET A SD  1 
ATOM   256   C CE  . MET A 1 37  ? -38.776  -25.146 43.010  1.00 69.36  ? 244 MET A CE  1 
ATOM   257   N N   . MET A 1 38  ? -39.967  -31.408 43.388  1.00 59.59  ? 245 MET A N   1 
ATOM   258   C CA  . MET A 1 38  ? -40.940  -32.304 42.716  1.00 60.56  ? 245 MET A CA  1 
ATOM   259   C C   . MET A 1 38  ? -41.570  -33.262 43.728  1.00 57.92  ? 245 MET A C   1 
ATOM   260   O O   . MET A 1 38  ? -40.822  -33.904 44.478  1.00 59.87  ? 245 MET A O   1 
ATOM   261   C CB  . MET A 1 38  ? -40.254  -33.113 41.615  1.00 60.70  ? 245 MET A CB  1 
ATOM   262   C CG  . MET A 1 38  ? -40.162  -32.378 40.306  1.00 60.60  ? 245 MET A CG  1 
ATOM   263   S SD  . MET A 1 38  ? -40.117  -33.534 38.932  1.00 67.33  ? 245 MET A SD  1 
ATOM   264   C CE  . MET A 1 38  ? -38.355  -33.614 38.639  1.00 56.06  ? 245 MET A CE  1 
ATOM   265   N N   . PRO A 1 39  ? -42.914  -33.369 43.771  1.00 61.91  ? 246 PRO A N   1 
ATOM   266   C CA  . PRO A 1 39  ? -43.610  -34.254 44.708  1.00 60.55  ? 246 PRO A CA  1 
ATOM   267   C C   . PRO A 1 39  ? -43.309  -35.749 44.536  1.00 69.11  ? 246 PRO A C   1 
ATOM   268   O O   . PRO A 1 39  ? -44.049  -36.433 43.860  1.00 74.31  ? 246 PRO A O   1 
ATOM   269   C CB  . PRO A 1 39  ? -45.087  -33.993 44.402  1.00 53.63  ? 246 PRO A CB  1 
ATOM   270   C CG  . PRO A 1 39  ? -45.098  -33.412 43.025  1.00 56.24  ? 246 PRO A CG  1 
ATOM   271   C CD  . PRO A 1 39  ? -43.835  -32.590 42.957  1.00 58.94  ? 246 PRO A CD  1 
ATOM   272   N N   . THR A 1 40  ? -42.243  -36.221 45.175  1.00 67.03  ? 247 THR A N   1 
ATOM   273   C CA  . THR A 1 40  ? -41.881  -37.654 45.096  1.00 76.82  ? 247 THR A CA  1 
ATOM   274   C C   . THR A 1 40  ? -42.161  -38.281 46.457  1.00 83.22  ? 247 THR A C   1 
ATOM   275   O O   . THR A 1 40  ? -41.284  -38.200 47.327  1.00 92.14  ? 247 THR A O   1 
ATOM   276   C CB  . THR A 1 40  ? -40.432  -37.827 44.633  1.00 74.47  ? 247 THR A CB  1 
ATOM   277   N N   . GLU A 1 41  ? -43.350  -38.852 46.626  1.00 87.10  ? 248 GLU A N   1 
ATOM   278   C CA  . GLU A 1 41  ? -43.754  -39.455 47.920  1.00 89.26  ? 248 GLU A CA  1 
ATOM   279   C C   . GLU A 1 41  ? -43.013  -40.776 48.123  1.00 94.94  ? 248 GLU A C   1 
ATOM   280   O O   . GLU A 1 41  ? -43.638  -41.718 48.640  1.00 90.15  ? 248 GLU A O   1 
ATOM   281   C CB  . GLU A 1 41  ? -45.260  -39.700 47.896  1.00 72.00  ? 248 GLU A CB  1 
ATOM   282   N N   . GLY A 1 42  ? -41.740  -40.855 47.723  1.00 90.71  ? 249 GLY A N   1 
ATOM   283   C CA  . GLY A 1 42  ? -40.991  -42.124 47.782  1.00 94.32  ? 249 GLY A CA  1 
ATOM   284   C C   . GLY A 1 42  ? -41.366  -43.016 46.614  1.00 98.53  ? 249 GLY A C   1 
ATOM   285   O O   . GLY A 1 42  ? -40.577  -43.934 46.337  1.00 96.94  ? 249 GLY A O   1 
ATOM   286   N N   . ASP A 1 43  ? -42.528  -42.762 46.001  1.00 94.39  ? 250 ASP A N   1 
ATOM   287   C CA  . ASP A 1 43  ? -43.029  -43.541 44.836  1.00 97.74  ? 250 ASP A CA  1 
ATOM   288   C C   . ASP A 1 43  ? -42.571  -44.999 44.946  1.00 102.20 ? 250 ASP A C   1 
ATOM   289   O O   . ASP A 1 43  ? -43.065  -45.698 45.852  1.00 103.15 ? 250 ASP A O   1 
ATOM   290   C CB  . ASP A 1 43  ? -42.665  -42.841 43.523  1.00 97.21  ? 250 ASP A CB  1 
ATOM   291   C CG  . ASP A 1 43  ? -43.077  -41.379 43.482  1.00 95.22  ? 250 ASP A CG  1 
ATOM   292   O OD1 . ASP A 1 43  ? -44.149  -41.055 44.022  1.00 96.31  ? 250 ASP A OD1 1 
ATOM   293   O OD2 . ASP A 1 43  ? -42.322  -40.579 42.906  1.00 86.12  ? 250 ASP A OD2 1 
ATOM   294   N N   . ASP A 1 44  ? -41.677  -45.432 44.057  1.00 96.68  ? 251 ASP A N   1 
ATOM   295   C CA  . ASP A 1 44  ? -41.149  -46.817 44.125  1.00 101.75 ? 251 ASP A CA  1 
ATOM   296   C C   . ASP A 1 44  ? -39.678  -46.831 43.698  1.00 106.72 ? 251 ASP A C   1 
ATOM   297   O O   . ASP A 1 44  ? -39.306  -47.836 43.084  1.00 105.61 ? 251 ASP A O   1 
ATOM   298   C CB  . ASP A 1 44  ? -42.033  -47.777 43.324  1.00 102.44 ? 251 ASP A CB  1 
ATOM   299   C CG  . ASP A 1 44  ? -42.965  -48.612 44.184  1.00 96.08  ? 251 ASP A CG  1 
ATOM   300   O OD1 . ASP A 1 44  ? -42.597  -48.903 45.338  1.00 96.92  ? 251 ASP A OD1 1 
ATOM   301   O OD2 . ASP A 1 44  ? -44.050  -48.965 43.690  1.00 90.15  ? 251 ASP A OD2 1 
ATOM   302   N N   . SER A 1 45  ? -38.895  -45.790 44.027  1.00 107.06 ? 252 SER A N   1 
ATOM   303   C CA  . SER A 1 45  ? -37.432  -45.681 43.730  1.00 106.48 ? 252 SER A CA  1 
ATOM   304   C C   . SER A 1 45  ? -37.048  -46.225 42.353  1.00 109.34 ? 252 SER A C   1 
ATOM   305   O O   . SER A 1 45  ? -36.818  -45.397 41.457  1.00 105.85 ? 252 SER A O   1 
ATOM   306   C CB  . SER A 1 45  ? -36.584  -46.298 44.820  1.00 103.58 ? 252 SER A CB  1 
ATOM   307   O OG  . SER A 1 45  ? -36.892  -47.670 45.019  1.00 103.92 ? 252 SER A OG  1 
ATOM   308   N N   . SER A 1 46  ? -36.950  -47.546 42.193  1.00 107.69 ? 253 SER A N   1 
ATOM   309   C CA  . SER A 1 46  ? -36.641  -48.193 40.892  1.00 100.97 ? 253 SER A CA  1 
ATOM   310   C C   . SER A 1 46  ? -37.724  -47.902 39.849  1.00 103.71 ? 253 SER A C   1 
ATOM   311   O O   . SER A 1 46  ? -37.667  -48.515 38.768  1.00 96.15  ? 253 SER A O   1 
ATOM   312   C CB  . SER A 1 46  ? -36.503  -49.666 41.098  1.00 104.11 ? 253 SER A CB  1 
ATOM   313   O OG  . SER A 1 46  ? -37.731  -50.234 41.530  1.00 103.73 ? 253 SER A OG  1 
ATOM   314   N N   . LYS A 1 47  ? -38.676  -47.025 40.161  1.00 103.41 ? 254 LYS A N   1 
ATOM   315   C CA  . LYS A 1 47  ? -39.726  -46.640 39.196  1.00 99.56  ? 254 LYS A CA  1 
ATOM   316   C C   . LYS A 1 47  ? -39.744  -45.123 39.016  1.00 94.06  ? 254 LYS A C   1 
ATOM   317   O O   . LYS A 1 47  ? -40.321  -44.679 38.013  1.00 94.60  ? 254 LYS A O   1 
ATOM   318   C CB  . LYS A 1 47  ? -41.083  -47.134 39.699  1.00 97.11  ? 254 LYS A CB  1 
ATOM   319   N N   . SER A 1 48  ? -39.133  -44.355 39.925  1.00 89.63  ? 255 SER A N   1 
ATOM   320   C CA  . SER A 1 48  ? -39.280  -42.882 39.771  1.00 89.30  ? 255 SER A CA  1 
ATOM   321   C C   . SER A 1 48  ? -38.018  -42.234 39.210  1.00 78.15  ? 255 SER A C   1 
ATOM   322   O O   . SER A 1 48  ? -37.029  -42.141 39.949  1.00 77.41  ? 255 SER A O   1 
ATOM   323   C CB  . SER A 1 48  ? -39.675  -42.235 41.068  1.00 87.44  ? 255 SER A CB  1 
ATOM   324   O OG  . SER A 1 48  ? -39.983  -40.863 40.877  1.00 78.04  ? 255 SER A OG  1 
ATOM   325   N N   . VAL A 1 49  ? -38.071  -41.791 37.957  1.00 71.91  ? 256 VAL A N   1 
ATOM   326   C CA  . VAL A 1 49  ? -36.923  -41.030 37.383  1.00 69.72  ? 256 VAL A CA  1 
ATOM   327   C C   . VAL A 1 49  ? -36.746  -39.731 38.183  1.00 69.04  ? 256 VAL A C   1 
ATOM   328   O O   . VAL A 1 49  ? -35.588  -39.435 38.506  1.00 68.54  ? 256 VAL A O   1 
ATOM   329   C CB  . VAL A 1 49  ? -37.063  -40.789 35.864  1.00 65.27  ? 256 VAL A CB  1 
ATOM   330   C CG1 . VAL A 1 49  ? -35.920  -39.968 35.296  1.00 60.96  ? 256 VAL A CG1 1 
ATOM   331   C CG2 . VAL A 1 49  ? -37.214  -42.089 35.094  1.00 64.53  ? 256 VAL A CG2 1 
ATOM   332   N N   . PRO A 1 50  ? -37.780  -38.931 38.552  1.00 67.26  ? 257 PRO A N   1 
ATOM   333   C CA  . PRO A 1 50  ? -37.509  -37.721 39.356  1.00 63.51  ? 257 PRO A CA  1 
ATOM   334   C C   . PRO A 1 50  ? -36.845  -38.011 40.693  1.00 63.36  ? 257 PRO A C   1 
ATOM   335   O O   . PRO A 1 50  ? -35.943  -37.264 41.104  1.00 55.22  ? 257 PRO A O   1 
ATOM   336   C CB  . PRO A 1 50  ? -38.902  -37.100 39.521  1.00 55.64  ? 257 PRO A CB  1 
ATOM   337   C CG  . PRO A 1 50  ? -39.655  -37.583 38.339  1.00 60.48  ? 257 PRO A CG  1 
ATOM   338   C CD  . PRO A 1 50  ? -39.191  -38.980 38.130  1.00 65.11  ? 257 PRO A CD  1 
ATOM   339   N N   . LEU A 1 51  ? -37.268  -39.077 41.385  1.00 63.58  ? 258 LEU A N   1 
ATOM   340   C CA  . LEU A 1 51  ? -36.617  -39.446 42.639  1.00 62.35  ? 258 LEU A CA  1 
ATOM   341   C C   . LEU A 1 51  ? -35.135  -39.730 42.420  1.00 62.28  ? 258 LEU A C   1 
ATOM   342   O O   . LEU A 1 51  ? -34.281  -39.245 43.174  1.00 60.30  ? 258 LEU A O   1 
ATOM   343   C CB  . LEU A 1 51  ? -37.322  -40.655 43.264  1.00 63.71  ? 258 LEU A CB  1 
ATOM   344   N N   . ALA A 1 52  ? -34.809  -40.491 41.375  1.00 61.06  ? 259 ALA A N   1 
ATOM   345   C CA  . ALA A 1 52  ? -33.414  -40.787 41.083  1.00 59.61  ? 259 ALA A CA  1 
ATOM   346   C C   . ALA A 1 52  ? -32.627  -39.509 40.813  1.00 62.76  ? 259 ALA A C   1 
ATOM   347   O O   . ALA A 1 52  ? -31.535  -39.307 41.362  1.00 57.26  ? 259 ALA A O   1 
ATOM   348   C CB  . ALA A 1 52  ? -33.334  -41.733 39.892  1.00 62.90  ? 259 ALA A CB  1 
ATOM   349   N N   . LEU A 1 53  ? -33.179  -38.632 39.965  1.00 64.04  ? 260 LEU A N   1 
ATOM   350   C CA  . LEU A 1 53  ? -32.558  -37.340 39.689  1.00 58.92  ? 260 LEU A CA  1 
ATOM   351   C C   . LEU A 1 53  ? -32.356  -36.543 40.964  1.00 59.48  ? 260 LEU A C   1 
ATOM   352   O O   . LEU A 1 53  ? -31.366  -35.814 41.100  1.00 58.45  ? 260 LEU A O   1 
ATOM   353   C CB  . LEU A 1 53  ? -33.421  -36.536 38.713  1.00 59.36  ? 260 LEU A CB  1 
ATOM   354   C CG  . LEU A 1 53  ? -32.982  -36.387 37.263  1.00 58.97  ? 260 LEU A CG  1 
ATOM   355   C CD1 . LEU A 1 53  ? -33.596  -35.129 36.704  1.00 54.90  ? 260 LEU A CD1 1 
ATOM   356   C CD2 . LEU A 1 53  ? -31.467  -36.361 37.137  1.00 56.57  ? 260 LEU A CD2 1 
ATOM   357   N N   . GLN A 1 54  ? -33.304  -36.647 41.899  1.00 61.34  ? 261 GLN A N   1 
ATOM   358   C CA  . GLN A 1 54  ? -33.154  -35.962 43.178  1.00 62.13  ? 261 GLN A CA  1 
ATOM   359   C C   . GLN A 1 54  ? -32.059  -36.596 44.019  1.00 59.93  ? 261 GLN A C   1 
ATOM   360   O O   . GLN A 1 54  ? -31.253  -35.881 44.630  1.00 56.90  ? 261 GLN A O   1 
ATOM   361   C CB  . GLN A 1 54  ? -34.463  -35.983 43.935  1.00 59.47  ? 261 GLN A CB  1 
ATOM   362   C CG  . GLN A 1 54  ? -35.496  -35.068 43.401  1.00 58.76  ? 261 GLN A CG  1 
ATOM   363   C CD  . GLN A 1 54  ? -36.796  -35.312 44.108  1.00 61.90  ? 261 GLN A CD  1 
ATOM   364   O OE1 . GLN A 1 54  ? -37.044  -36.429 44.586  1.00 54.12  ? 261 GLN A OE1 1 
ATOM   365   N NE2 . GLN A 1 54  ? -37.634  -34.276 44.206  1.00 60.38  ? 261 GLN A NE2 1 
ATOM   366   N N   . ARG A 1 55  ? -32.019  -37.931 44.071  1.00 56.70  ? 262 ARG A N   1 
ATOM   367   C CA  . ARG A 1 55  ? -30.902  -38.605 44.725  1.00 58.07  ? 262 ARG A CA  1 
ATOM   368   C C   . ARG A 1 55  ? -29.582  -38.123 44.141  1.00 61.36  ? 262 ARG A C   1 
ATOM   369   O O   . ARG A 1 55  ? -28.771  -37.501 44.836  1.00 63.59  ? 262 ARG A O   1 
ATOM   370   C CB  . ARG A 1 55  ? -31.033  -40.125 44.594  1.00 54.96  ? 262 ARG A CB  1 
ATOM   371   N N   . VAL A 1 56  ? -29.380  -38.350 42.839  1.00 58.38  ? 263 VAL A N   1 
ATOM   372   C CA  . VAL A 1 56  ? -28.105  -38.011 42.211  1.00 59.10  ? 263 VAL A CA  1 
ATOM   373   C C   . VAL A 1 56  ? -27.783  -36.538 42.400  1.00 59.84  ? 263 VAL A C   1 
ATOM   374   O O   . VAL A 1 56  ? -26.646  -36.178 42.715  1.00 62.48  ? 263 VAL A O   1 
ATOM   375   C CB  . VAL A 1 56  ? -28.105  -38.391 40.722  1.00 57.88  ? 263 VAL A CB  1 
ATOM   376   C CG1 . VAL A 1 56  ? -26.953  -37.713 40.038  1.00 53.61  ? 263 VAL A CG1 1 
ATOM   377   C CG2 . VAL A 1 56  ? -27.987  -39.887 40.567  1.00 56.32  ? 263 VAL A CG2 1 
ATOM   378   N N   . PHE A 1 57  ? -28.770  -35.662 42.223  1.00 61.68  ? 264 PHE A N   1 
ATOM   379   C CA  . PHE A 1 57  ? -28.506  -34.243 42.436  1.00 60.15  ? 264 PHE A CA  1 
ATOM   380   C C   . PHE A 1 57  ? -28.175  -33.951 43.890  1.00 62.81  ? 264 PHE A C   1 
ATOM   381   O O   . PHE A 1 57  ? -27.310  -33.113 44.167  1.00 63.92  ? 264 PHE A O   1 
ATOM   382   C CB  . PHE A 1 57  ? -29.694  -33.397 41.996  1.00 61.62  ? 264 PHE A CB  1 
ATOM   383   C CG  . PHE A 1 57  ? -29.826  -33.269 40.502  1.00 67.01  ? 264 PHE A CG  1 
ATOM   384   C CD1 . PHE A 1 57  ? -28.895  -33.852 39.650  1.00 63.44  ? 264 PHE A CD1 1 
ATOM   385   C CD2 . PHE A 1 57  ? -30.893  -32.570 39.948  1.00 62.41  ? 264 PHE A CD2 1 
ATOM   386   C CE1 . PHE A 1 57  ? -29.019  -33.729 38.281  1.00 61.65  ? 264 PHE A CE1 1 
ATOM   387   C CE2 . PHE A 1 57  ? -31.022  -32.449 38.588  1.00 61.61  ? 264 PHE A CE2 1 
ATOM   388   C CZ  . PHE A 1 57  ? -30.085  -33.023 37.749  1.00 60.87  ? 264 PHE A CZ  1 
ATOM   389   N N   . TYR A 1 58  ? -28.808  -34.632 44.840  1.00 66.03  ? 265 TYR A N   1 
ATOM   390   C CA  . TYR A 1 58  ? -28.569  -34.300 46.268  1.00 68.26  ? 265 TYR A CA  1 
ATOM   391   C C   . TYR A 1 58  ? -27.138  -34.641 46.635  1.00 68.24  ? 265 TYR A C   1 
ATOM   392   O O   . TYR A 1 58  ? -26.498  -33.869 47.339  1.00 69.37  ? 265 TYR A O   1 
ATOM   393   C CB  . TYR A 1 58  ? -29.490  -35.083 47.205  1.00 67.05  ? 265 TYR A CB  1 
ATOM   394   C CG  . TYR A 1 58  ? -29.263  -34.871 48.681  1.00 65.33  ? 265 TYR A CG  1 
ATOM   395   C CD1 . TYR A 1 58  ? -29.857  -33.814 49.343  1.00 61.36  ? 265 TYR A CD1 1 
ATOM   396   C CD2 . TYR A 1 58  ? -28.474  -35.734 49.424  1.00 66.73  ? 265 TYR A CD2 1 
ATOM   397   C CE1 . TYR A 1 58  ? -29.660  -33.604 50.696  1.00 65.53  ? 265 TYR A CE1 1 
ATOM   398   C CE2 . TYR A 1 58  ? -28.257  -35.533 50.775  1.00 68.83  ? 265 TYR A CE2 1 
ATOM   399   C CZ  . TYR A 1 58  ? -28.856  -34.465 51.416  1.00 69.24  ? 265 TYR A CZ  1 
ATOM   400   O OH  . TYR A 1 58  ? -28.656  -34.261 52.749  1.00 78.91  ? 265 TYR A OH  1 
ATOM   401   N N   . GLU A 1 59  ? -26.678  -35.800 46.194  1.00 62.47  ? 266 GLU A N   1 
ATOM   402   C CA  . GLU A 1 59  ? -25.339  -36.250 46.620  1.00 69.80  ? 266 GLU A CA  1 
ATOM   403   C C   . GLU A 1 59  ? -24.267  -35.472 45.861  1.00 74.18  ? 266 GLU A C   1 
ATOM   404   O O   . GLU A 1 59  ? -23.233  -35.192 46.453  1.00 81.85  ? 266 GLU A O   1 
ATOM   405   C CB  . GLU A 1 59  ? -25.233  -37.756 46.420  1.00 64.72  ? 266 GLU A CB  1 
ATOM   406   C CG  . GLU A 1 59  ? -25.691  -38.549 47.624  1.00 73.65  ? 266 GLU A CG  1 
ATOM   407   C CD  . GLU A 1 59  ? -26.633  -39.687 47.280  1.00 85.54  ? 266 GLU A CD  1 
ATOM   408   O OE1 . GLU A 1 59  ? -27.719  -39.753 47.885  1.00 87.98  ? 266 GLU A OE1 1 
ATOM   409   O OE2 . GLU A 1 59  ? -26.278  -40.500 46.408  1.00 82.45  ? 266 GLU A OE2 1 
ATOM   410   N N   . LEU A 1 60  ? -24.511  -35.106 44.610  1.00 69.98  ? 267 LEU A N   1 
ATOM   411   C CA  . LEU A 1 60  ? -23.508  -34.287 43.900  1.00 65.66  ? 267 LEU A CA  1 
ATOM   412   C C   . LEU A 1 60  ? -23.379  -32.964 44.658  1.00 69.39  ? 267 LEU A C   1 
ATOM   413   O O   . LEU A 1 60  ? -22.315  -32.345 44.559  1.00 76.98  ? 267 LEU A O   1 
ATOM   414   C CB  . LEU A 1 60  ? -23.975  -34.063 42.464  1.00 68.67  ? 267 LEU A CB  1 
ATOM   415   C CG  . LEU A 1 60  ? -23.576  -35.122 41.446  1.00 62.78  ? 267 LEU A CG  1 
ATOM   416   C CD1 . LEU A 1 60  ? -24.318  -34.889 40.143  1.00 59.82  ? 267 LEU A CD1 1 
ATOM   417   C CD2 . LEU A 1 60  ? -22.078  -35.091 41.213  1.00 62.20  ? 267 LEU A CD2 1 
ATOM   418   N N   . GLN A 1 61  ? -24.418  -32.554 45.392  1.00 67.26  ? 268 GLN A N   1 
ATOM   419   C CA  . GLN A 1 61  ? -24.339  -31.331 46.162  1.00 64.93  ? 268 GLN A CA  1 
ATOM   420   C C   . GLN A 1 61  ? -23.679  -31.535 47.514  1.00 72.10  ? 268 GLN A C   1 
ATOM   421   O O   . GLN A 1 61  ? -23.225  -30.551 48.106  1.00 80.41  ? 268 GLN A O   1 
ATOM   422   C CB  . GLN A 1 61  ? -25.736  -30.754 46.364  1.00 65.26  ? 268 GLN A CB  1 
ATOM   423   C CG  . GLN A 1 61  ? -25.819  -29.257 46.407  1.00 59.54  ? 268 GLN A CG  1 
ATOM   424   C CD  . GLN A 1 61  ? -27.252  -28.785 46.475  1.00 63.11  ? 268 GLN A CD  1 
ATOM   425   O OE1 . GLN A 1 61  ? -28.097  -29.254 45.711  1.00 63.08  ? 268 GLN A OE1 1 
ATOM   426   N NE2 . GLN A 1 61  ? -27.541  -27.852 47.385  1.00 64.00  ? 268 GLN A NE2 1 
ATOM   427   N N   . HIS A 1 62  ? -23.662  -32.766 48.032  1.00 75.16  ? 269 HIS A N   1 
ATOM   428   C CA  . HIS A 1 62  ? -23.209  -32.978 49.433  1.00 79.05  ? 269 HIS A CA  1 
ATOM   429   C C   . HIS A 1 62  ? -22.008  -33.915 49.581  1.00 77.53  ? 269 HIS A C   1 
ATOM   430   O O   . HIS A 1 62  ? -21.148  -33.612 50.422  1.00 79.73  ? 269 HIS A O   1 
ATOM   431   C CB  . HIS A 1 62  ? -24.378  -33.562 50.225  1.00 72.03  ? 269 HIS A CB  1 
ATOM   432   C CG  . HIS A 1 62  ? -25.478  -32.601 50.507  1.00 76.35  ? 269 HIS A CG  1 
ATOM   433   N ND1 . HIS A 1 62  ? -26.242  -32.037 49.513  1.00 75.84  ? 269 HIS A ND1 1 
ATOM   434   C CD2 . HIS A 1 62  ? -25.956  -32.118 51.669  1.00 84.85  ? 269 HIS A CD2 1 
ATOM   435   C CE1 . HIS A 1 62  ? -27.133  -31.236 50.042  1.00 73.57  ? 269 HIS A CE1 1 
ATOM   436   N NE2 . HIS A 1 62  ? -26.987  -31.279 51.362  1.00 81.46  ? 269 HIS A NE2 1 
ATOM   437   N N   . SER A 1 63  ? -21.942  -34.994 48.801  1.00 72.84  ? 270 SER A N   1 
ATOM   438   C CA  . SER A 1 63  ? -20.871  -36.022 48.936  1.00 80.21  ? 270 SER A CA  1 
ATOM   439   C C   . SER A 1 63  ? -19.460  -35.454 48.802  1.00 87.18  ? 270 SER A C   1 
ATOM   440   O O   . SER A 1 63  ? -19.287  -34.411 48.150  1.00 88.17  ? 270 SER A O   1 
ATOM   441   C CB  . SER A 1 63  ? -21.058  -37.119 47.929  1.00 74.25  ? 270 SER A CB  1 
ATOM   442   O OG  . SER A 1 63  ? -20.218  -38.224 48.219  1.00 77.57  ? 270 SER A OG  1 
ATOM   443   N N   . ASP A 1 64  ? -18.483  -36.155 49.378  1.00 83.92  ? 271 ASP A N   1 
ATOM   444   C CA  . ASP A 1 64  ? -17.066  -35.737 49.230  1.00 83.26  ? 271 ASP A CA  1 
ATOM   445   C C   . ASP A 1 64  ? -16.346  -36.871 48.511  1.00 85.40  ? 271 ASP A C   1 
ATOM   446   O O   . ASP A 1 64  ? -15.107  -36.915 48.570  1.00 90.80  ? 271 ASP A O   1 
ATOM   447   C CB  . ASP A 1 64  ? -16.431  -35.396 50.579  1.00 87.99  ? 271 ASP A CB  1 
ATOM   448   C CG  . ASP A 1 64  ? -16.714  -36.422 51.662  1.00 102.65 ? 271 ASP A CG  1 
ATOM   449   O OD1 . ASP A 1 64  ? -17.838  -36.414 52.200  1.00 101.02 ? 271 ASP A OD1 1 
ATOM   450   O OD2 . ASP A 1 64  ? -15.805  -37.218 51.961  1.00 106.40 ? 271 ASP A OD2 1 
ATOM   451   N N   . LYS A 1 65  ? -17.117  -37.744 47.861  1.00 84.05  ? 272 LYS A N   1 
ATOM   452   C CA  . LYS A 1 65  ? -16.559  -38.883 47.095  1.00 81.06  ? 272 LYS A CA  1 
ATOM   453   C C   . LYS A 1 65  ? -17.436  -39.095 45.858  1.00 85.30  ? 272 LYS A C   1 
ATOM   454   O O   . LYS A 1 65  ? -18.633  -38.775 45.931  1.00 85.97  ? 272 LYS A O   1 
ATOM   455   C CB  . LYS A 1 65  ? -16.540  -40.132 47.977  1.00 75.95  ? 272 LYS A CB  1 
ATOM   456   N N   . PRO A 1 66  ? -16.900  -39.590 44.723  1.00 83.64  ? 273 PRO A N   1 
ATOM   457   C CA  . PRO A 1 66  ? -17.703  -39.877 43.528  1.00 77.90  ? 273 PRO A CA  1 
ATOM   458   C C   . PRO A 1 66  ? -19.109  -40.453 43.762  1.00 79.04  ? 273 PRO A C   1 
ATOM   459   O O   . PRO A 1 66  ? -19.233  -41.391 44.522  1.00 79.44  ? 273 PRO A O   1 
ATOM   460   C CB  . PRO A 1 66  ? -16.814  -40.905 42.827  1.00 76.11  ? 273 PRO A CB  1 
ATOM   461   C CG  . PRO A 1 66  ? -15.426  -40.380 43.074  1.00 79.87  ? 273 PRO A CG  1 
ATOM   462   C CD  . PRO A 1 66  ? -15.476  -39.846 44.490  1.00 77.10  ? 273 PRO A CD  1 
ATOM   463   N N   . VAL A 1 67  ? -20.114  -39.911 43.067  1.00 76.47  ? 274 VAL A N   1 
ATOM   464   C CA  . VAL A 1 67  ? -21.536  -40.336 43.236  1.00 69.01  ? 274 VAL A CA  1 
ATOM   465   C C   . VAL A 1 67  ? -21.871  -41.444 42.234  1.00 67.34  ? 274 VAL A C   1 
ATOM   466   O O   . VAL A 1 67  ? -21.253  -41.478 41.185  1.00 70.74  ? 274 VAL A O   1 
ATOM   467   C CB  . VAL A 1 67  ? -22.461  -39.111 43.096  1.00 63.60  ? 274 VAL A CB  1 
ATOM   468   C CG1 . VAL A 1 67  ? -23.921  -39.414 43.383  1.00 69.84  ? 274 VAL A CG1 1 
ATOM   469   C CG2 . VAL A 1 67  ? -21.983  -37.956 43.957  1.00 62.31  ? 274 VAL A CG2 1 
ATOM   470   N N   . GLY A 1 68  ? -22.829  -42.311 42.551  1.00 63.85  ? 275 GLY A N   1 
ATOM   471   C CA  . GLY A 1 68  ? -23.203  -43.428 41.707  1.00 66.04  ? 275 GLY A CA  1 
ATOM   472   C C   . GLY A 1 68  ? -24.473  -43.157 40.908  1.00 79.30  ? 275 GLY A C   1 
ATOM   473   O O   . GLY A 1 68  ? -25.218  -42.215 41.162  1.00 82.54  ? 275 GLY A O   1 
ATOM   474   N N   . THR A 1 69  ? -24.696  -44.006 39.904  1.00 76.14  ? 276 THR A N   1 
ATOM   475   C CA  . THR A 1 69  ? -25.785  -43.838 38.943  1.00 70.76  ? 276 THR A CA  1 
ATOM   476   C C   . THR A 1 69  ? -26.720  -45.031 38.917  1.00 74.03  ? 276 THR A C   1 
ATOM   477   O O   . THR A 1 69  ? -27.606  -45.099 38.052  1.00 71.14  ? 276 THR A O   1 
ATOM   478   C CB  . THR A 1 69  ? -25.245  -43.633 37.522  1.00 80.56  ? 276 THR A CB  1 
ATOM   479   O OG1 . THR A 1 69  ? -25.073  -44.917 36.882  1.00 81.08  ? 276 THR A OG1 1 
ATOM   480   C CG2 . THR A 1 69  ? -23.904  -42.871 37.530  1.00 75.88  ? 276 THR A CG2 1 
ATOM   481   N N   . LYS A 1 70  ? -26.449  -46.015 39.768  1.00 74.88  ? 277 LYS A N   1 
ATOM   482   C CA  . LYS A 1 70  ? -27.190  -47.300 39.752  1.00 65.18  ? 277 LYS A CA  1 
ATOM   483   C C   . LYS A 1 70  ? -28.698  -47.116 39.774  1.00 70.92  ? 277 LYS A C   1 
ATOM   484   O O   . LYS A 1 70  ? -29.364  -47.661 38.889  1.00 69.29  ? 277 LYS A O   1 
ATOM   485   C CB  . LYS A 1 70  ? -26.797  -48.109 40.989  1.00 61.81  ? 277 LYS A CB  1 
ATOM   486   C CG  . LYS A 1 70  ? -25.638  -47.562 41.811  1.00 69.44  ? 277 LYS A CG  1 
ATOM   487   C CD  . LYS A 1 70  ? -26.045  -47.131 43.201  1.00 67.99  ? 277 LYS A CD  1 
ATOM   488   C CE  . LYS A 1 70  ? -25.071  -46.159 43.829  1.00 62.81  ? 277 LYS A CE  1 
ATOM   489   N NZ  . LYS A 1 70  ? -23.705  -46.725 43.908  1.00 62.31  ? 277 LYS A NZ  1 
ATOM   490   N N   . LYS A 1 71  ? -29.206  -46.396 40.761  1.00 67.32  ? 278 LYS A N   1 
ATOM   491   C CA  . LYS A 1 71  ? -30.650  -46.283 40.940  1.00 66.98  ? 278 LYS A CA  1 
ATOM   492   C C   . LYS A 1 71  ? -31.306  -45.579 39.752  1.00 73.92  ? 278 LYS A C   1 
ATOM   493   O O   . LYS A 1 71  ? -32.412  -45.951 39.331  1.00 69.28  ? 278 LYS A O   1 
ATOM   494   C CB  . LYS A 1 71  ? -30.948  -45.548 42.249  1.00 68.71  ? 278 LYS A CB  1 
ATOM   495   N N   . LEU A 1 72  ? -30.624  -44.575 39.187  1.00 73.18  ? 279 LEU A N   1 
ATOM   496   C CA  . LEU A 1 72  ? -31.163  -43.823 38.053  1.00 68.66  ? 279 LEU A CA  1 
ATOM   497   C C   . LEU A 1 72  ? -31.328  -44.705 36.822  1.00 66.67  ? 279 LEU A C   1 
ATOM   498   O O   . LEU A 1 72  ? -32.365  -44.671 36.148  1.00 65.46  ? 279 LEU A O   1 
ATOM   499   C CB  . LEU A 1 72  ? -30.252  -42.640 37.733  1.00 61.93  ? 279 LEU A CB  1 
ATOM   500   C CG  . LEU A 1 72  ? -30.612  -41.881 36.459  1.00 63.49  ? 279 LEU A CG  1 
ATOM   501   C CD1 . LEU A 1 72  ? -32.077  -41.439 36.489  1.00 65.56  ? 279 LEU A CD1 1 
ATOM   502   C CD2 . LEU A 1 72  ? -29.687  -40.697 36.253  1.00 58.58  ? 279 LEU A CD2 1 
ATOM   503   N N   . THR A 1 73  ? -30.300  -45.475 36.488  1.00 68.44  ? 280 THR A N   1 
ATOM   504   C CA  . THR A 1 73  ? -30.439  -46.409 35.382  1.00 67.49  ? 280 THR A CA  1 
ATOM   505   C C   . THR A 1 73  ? -31.468  -47.490 35.704  1.00 67.02  ? 280 THR A C   1 
ATOM   506   O O   . THR A 1 73  ? -32.164  -47.975 34.805  1.00 62.76  ? 280 THR A O   1 
ATOM   507   C CB  . THR A 1 73  ? -29.075  -46.992 35.062  1.00 61.51  ? 280 THR A CB  1 
ATOM   508   O OG1 . THR A 1 73  ? -28.351  -47.160 36.284  1.00 65.91  ? 280 THR A OG1 1 
ATOM   509   C CG2 . THR A 1 73  ? -28.331  -46.016 34.249  1.00 56.97  ? 280 THR A CG2 1 
ATOM   510   N N   . LYS A 1 74  ? -31.594  -47.857 36.983  1.00 67.94  ? 281 LYS A N   1 
ATOM   511   C CA  . LYS A 1 74  ? -32.694  -48.710 37.405  1.00 64.29  ? 281 LYS A CA  1 
ATOM   512   C C   . LYS A 1 74  ? -34.015  -48.076 37.027  1.00 72.60  ? 281 LYS A C   1 
ATOM   513   O O   . LYS A 1 74  ? -34.808  -48.657 36.279  1.00 78.21  ? 281 LYS A O   1 
ATOM   514   C CB  . LYS A 1 74  ? -32.631  -48.953 38.912  1.00 65.72  ? 281 LYS A CB  1 
ATOM   515   N N   . SER A 1 75  ? -34.248  -46.852 37.510  1.00 74.74  ? 282 SER A N   1 
ATOM   516   C CA  . SER A 1 75  ? -35.468  -46.112 37.203  1.00 69.76  ? 282 SER A CA  1 
ATOM   517   C C   . SER A 1 75  ? -35.742  -45.982 35.714  1.00 64.66  ? 282 SER A C   1 
ATOM   518   O O   . SER A 1 75  ? -36.879  -45.694 35.331  1.00 68.18  ? 282 SER A O   1 
ATOM   519   C CB  . SER A 1 75  ? -35.377  -44.713 37.789  1.00 76.06  ? 282 SER A CB  1 
ATOM   520   O OG  . SER A 1 75  ? -34.725  -43.844 36.871  1.00 77.15  ? 282 SER A OG  1 
ATOM   521   N N   . PHE A 1 76  ? -34.727  -46.141 34.864  1.00 66.77  ? 283 PHE A N   1 
ATOM   522   C CA  . PHE A 1 76  ? -34.971  -46.154 33.428  1.00 70.97  ? 283 PHE A CA  1 
ATOM   523   C C   . PHE A 1 76  ? -35.664  -47.419 32.967  1.00 71.81  ? 283 PHE A C   1 
ATOM   524   O O   . PHE A 1 76  ? -36.142  -47.458 31.828  1.00 72.56  ? 283 PHE A O   1 
ATOM   525   C CB  . PHE A 1 76  ? -33.667  -46.008 32.642  1.00 70.41  ? 283 PHE A CB  1 
ATOM   526   C CG  . PHE A 1 76  ? -33.084  -44.640 32.700  1.00 69.71  ? 283 PHE A CG  1 
ATOM   527   C CD1 . PHE A 1 76  ? -33.867  -43.561 33.071  1.00 69.62  ? 283 PHE A CD1 1 
ATOM   528   C CD2 . PHE A 1 76  ? -31.757  -44.426 32.389  1.00 65.72  ? 283 PHE A CD2 1 
ATOM   529   C CE1 . PHE A 1 76  ? -33.336  -42.289 33.141  1.00 66.90  ? 283 PHE A CE1 1 
ATOM   530   C CE2 . PHE A 1 76  ? -31.221  -43.159 32.457  1.00 70.07  ? 283 PHE A CE2 1 
ATOM   531   C CZ  . PHE A 1 76  ? -32.017  -42.083 32.830  1.00 66.06  ? 283 PHE A CZ  1 
ATOM   532   N N   . GLY A 1 77  ? -35.738  -48.437 33.817  1.00 67.09  ? 284 GLY A N   1 
ATOM   533   C CA  . GLY A 1 77  ? -36.158  -49.748 33.385  1.00 70.37  ? 284 GLY A CA  1 
ATOM   534   C C   . GLY A 1 77  ? -35.043  -50.590 32.819  1.00 69.95  ? 284 GLY A C   1 
ATOM   535   O O   . GLY A 1 77  ? -35.322  -51.565 32.114  1.00 71.27  ? 284 GLY A O   1 
ATOM   536   N N   . TRP A 1 78  ? -33.791  -50.259 33.125  1.00 73.03  ? 285 TRP A N   1 
ATOM   537   C CA  . TRP A 1 78  ? -32.616  -50.886 32.533  1.00 73.11  ? 285 TRP A CA  1 
ATOM   538   C C   . TRP A 1 78  ? -32.051  -51.995 33.414  1.00 70.91  ? 285 TRP A C   1 
ATOM   539   O O   . TRP A 1 78  ? -32.108  -51.927 34.644  1.00 68.49  ? 285 TRP A O   1 
ATOM   540   C CB  . TRP A 1 78  ? -31.527  -49.843 32.296  1.00 67.56  ? 285 TRP A CB  1 
ATOM   541   C CG  . TRP A 1 78  ? -31.801  -48.967 31.144  1.00 70.04  ? 285 TRP A CG  1 
ATOM   542   C CD1 . TRP A 1 78  ? -32.936  -48.937 30.377  1.00 71.40  ? 285 TRP A CD1 1 
ATOM   543   C CD2 . TRP A 1 78  ? -30.921  -47.987 30.600  1.00 70.94  ? 285 TRP A CD2 1 
ATOM   544   N NE1 . TRP A 1 78  ? -32.811  -47.994 29.385  1.00 72.83  ? 285 TRP A NE1 1 
ATOM   545   C CE2 . TRP A 1 78  ? -31.581  -47.397 29.500  1.00 74.51  ? 285 TRP A CE2 1 
ATOM   546   C CE3 . TRP A 1 78  ? -29.633  -47.550 30.933  1.00 66.49  ? 285 TRP A CE3 1 
ATOM   547   C CZ2 . TRP A 1 78  ? -30.996  -46.394 28.737  1.00 73.47  ? 285 TRP A CZ2 1 
ATOM   548   C CZ3 . TRP A 1 78  ? -29.055  -46.561 30.173  1.00 61.55  ? 285 TRP A CZ3 1 
ATOM   549   C CH2 . TRP A 1 78  ? -29.734  -45.992 29.091  1.00 69.05  ? 285 TRP A CH2 1 
ATOM   550   N N   . GLU A 1 79  ? -31.486  -53.010 32.761  1.00 73.70  ? 286 GLU A N   1 
ATOM   551   C CA  . GLU A 1 79  ? -30.643  -54.009 33.404  1.00 76.16  ? 286 GLU A CA  1 
ATOM   552   C C   . GLU A 1 79  ? -29.184  -53.526 33.419  1.00 82.83  ? 286 GLU A C   1 
ATOM   553   O O   . GLU A 1 79  ? -28.813  -52.570 32.729  1.00 85.19  ? 286 GLU A O   1 
ATOM   554   C CB  . GLU A 1 79  ? -30.776  -55.357 32.687  1.00 75.34  ? 286 GLU A CB  1 
ATOM   555   N N   . THR A 1 80  ? -28.341  -54.194 34.207  1.00 84.83  ? 287 THR A N   1 
ATOM   556   C CA  . THR A 1 80  ? -26.932  -53.731 34.369  1.00 81.13  ? 287 THR A CA  1 
ATOM   557   C C   . THR A 1 80  ? -26.103  -53.964 33.105  1.00 81.46  ? 287 THR A C   1 
ATOM   558   O O   . THR A 1 80  ? -24.984  -53.438 33.057  1.00 83.43  ? 287 THR A O   1 
ATOM   559   C CB  . THR A 1 80  ? -26.279  -54.341 35.616  1.00 79.38  ? 287 THR A CB  1 
ATOM   560   O OG1 . THR A 1 80  ? -26.364  -55.763 35.518  1.00 85.89  ? 287 THR A OG1 1 
ATOM   561   C CG2 . THR A 1 80  ? -26.927  -53.878 36.902  1.00 74.07  ? 287 THR A CG2 1 
ATOM   562   N N   . LEU A 1 81  ? -26.589  -54.752 32.142  1.00 83.15  ? 288 LEU A N   1 
ATOM   563   C CA  . LEU A 1 81  ? -25.834  -54.831 30.897  1.00 84.15  ? 288 LEU A CA  1 
ATOM   564   C C   . LEU A 1 81  ? -26.036  -53.573 30.057  1.00 80.35  ? 288 LEU A C   1 
ATOM   565   O O   . LEU A 1 81  ? -25.115  -53.128 29.363  1.00 72.42  ? 288 LEU A O   1 
ATOM   566   C CB  . LEU A 1 81  ? -26.239  -56.079 30.111  1.00 91.70  ? 288 LEU A CB  1 
ATOM   567   N N   . ASP A 1 82  ? -27.234  -52.981 30.131  1.00 81.20  ? 289 ASP A N   1 
ATOM   568   C CA  . ASP A 1 82  ? -27.519  -51.715 29.468  1.00 77.72  ? 289 ASP A CA  1 
ATOM   569   C C   . ASP A 1 82  ? -26.646  -50.582 29.975  1.00 74.86  ? 289 ASP A C   1 
ATOM   570   O O   . ASP A 1 82  ? -26.595  -49.534 29.319  1.00 76.59  ? 289 ASP A O   1 
ATOM   571   C CB  . ASP A 1 82  ? -28.983  -51.324 29.655  1.00 69.82  ? 289 ASP A CB  1 
ATOM   572   C CG  . ASP A 1 82  ? -29.937  -52.361 29.128  1.00 72.03  ? 289 ASP A CG  1 
ATOM   573   O OD1 . ASP A 1 82  ? -29.623  -52.984 28.099  1.00 82.86  ? 289 ASP A OD1 1 
ATOM   574   O OD2 . ASP A 1 82  ? -31.008  -52.552 29.740  1.00 70.31  ? 289 ASP A OD2 1 
ATOM   575   N N   . SER A 1 83  ? -25.988  -50.751 31.127  1.00 68.98  ? 290 SER A N   1 
ATOM   576   C CA  . SER A 1 83  ? -25.069  -49.748 31.656  1.00 72.73  ? 290 SER A CA  1 
ATOM   577   C C   . SER A 1 83  ? -23.713  -49.755 30.963  1.00 74.83  ? 290 SER A C   1 
ATOM   578   O O   . SER A 1 83  ? -22.872  -48.893 31.262  1.00 72.66  ? 290 SER A O   1 
ATOM   579   C CB  . SER A 1 83  ? -24.857  -49.945 33.162  1.00 70.74  ? 290 SER A CB  1 
ATOM   580   O OG  . SER A 1 83  ? -25.784  -49.202 33.932  1.00 68.37  ? 290 SER A OG  1 
ATOM   581   N N   . PHE A 1 84  ? -23.481  -50.699 30.053  1.00 72.87  ? 291 PHE A N   1 
ATOM   582   C CA  . PHE A 1 84  ? -22.207  -50.810 29.362  1.00 73.04  ? 291 PHE A CA  1 
ATOM   583   C C   . PHE A 1 84  ? -22.365  -50.710 27.843  1.00 72.43  ? 291 PHE A C   1 
ATOM   584   O O   . PHE A 1 84  ? -21.388  -50.904 27.109  1.00 72.86  ? 291 PHE A O   1 
ATOM   585   C CB  . PHE A 1 84  ? -21.500  -52.110 29.786  1.00 71.10  ? 291 PHE A CB  1 
ATOM   586   N N   . MET A 1 85  ? -23.564  -50.409 27.349  1.00 75.73  ? 292 MET A N   1 
ATOM   587   C CA  . MET A 1 85  ? -23.714  -49.954 25.973  1.00 72.58  ? 292 MET A CA  1 
ATOM   588   C C   . MET A 1 85  ? -23.436  -48.462 25.899  1.00 68.81  ? 292 MET A C   1 
ATOM   589   O O   . MET A 1 85  ? -23.873  -47.695 26.760  1.00 62.48  ? 292 MET A O   1 
ATOM   590   C CB  . MET A 1 85  ? -25.116  -50.226 25.440  1.00 70.66  ? 292 MET A CB  1 
ATOM   591   C CG  . MET A 1 85  ? -25.330  -49.658 24.041  1.00 66.12  ? 292 MET A CG  1 
ATOM   592   S SD  . MET A 1 85  ? -26.782  -50.367 23.259  1.00 78.41  ? 292 MET A SD  1 
ATOM   593   C CE  . MET A 1 85  ? -27.824  -50.624 24.708  1.00 75.99  ? 292 MET A CE  1 
ATOM   594   N N   . GLN A 1 86  ? -22.702  -48.074 24.856  1.00 71.95  ? 293 GLN A N   1 
ATOM   595   C CA  . GLN A 1 86  ? -22.343  -46.656 24.624  1.00 66.75  ? 293 GLN A CA  1 
ATOM   596   C C   . GLN A 1 86  ? -23.540  -45.941 24.009  1.00 67.70  ? 293 GLN A C   1 
ATOM   597   O O   . GLN A 1 86  ? -24.278  -46.582 23.249  1.00 59.23  ? 293 GLN A O   1 
ATOM   598   C CB  . GLN A 1 86  ? -21.103  -46.632 23.738  1.00 69.07  ? 293 GLN A CB  1 
ATOM   599   C CG  . GLN A 1 86  ? -20.053  -47.657 24.131  1.00 71.20  ? 293 GLN A CG  1 
ATOM   600   C CD  . GLN A 1 86  ? -18.725  -47.008 24.425  1.00 65.70  ? 293 GLN A CD  1 
ATOM   601   O OE1 . GLN A 1 86  ? -18.184  -46.271 23.610  1.00 64.50  ? 293 GLN A OE1 1 
ATOM   602   N NE2 . GLN A 1 86  ? -18.194  -47.273 25.605  1.00 71.61  ? 293 GLN A NE2 1 
ATOM   603   N N   . HIS A 1 87  ? -23.665  -44.638 24.239  1.00 64.04  ? 294 HIS A N   1 
ATOM   604   C CA  . HIS A 1 87  ? -24.878  -43.940 23.855  1.00 60.16  ? 294 HIS A CA  1 
ATOM   605   C C   . HIS A 1 87  ? -24.583  -42.491 23.475  1.00 63.35  ? 294 HIS A C   1 
ATOM   606   O O   . HIS A 1 87  ? -23.545  -41.922 23.837  1.00 59.30  ? 294 HIS A O   1 
ATOM   607   C CB  . HIS A 1 87  ? -25.885  -44.026 24.997  1.00 61.08  ? 294 HIS A CB  1 
ATOM   608   C CG  . HIS A 1 87  ? -26.751  -45.240 24.930  1.00 60.56  ? 294 HIS A CG  1 
ATOM   609   N ND1 . HIS A 1 87  ? -27.379  -45.633 23.770  1.00 62.28  ? 294 HIS A ND1 1 
ATOM   610   C CD2 . HIS A 1 87  ? -27.096  -46.147 25.872  1.00 57.67  ? 294 HIS A CD2 1 
ATOM   611   C CE1 . HIS A 1 87  ? -28.077  -46.730 24.001  1.00 58.61  ? 294 HIS A CE1 1 
ATOM   612   N NE2 . HIS A 1 87  ? -27.920  -47.064 25.268  1.00 59.08  ? 294 HIS A NE2 1 
ATOM   613   N N   . ASP A 1 88  ? -25.518  -41.897 22.728  1.00 58.85  ? 295 ASP A N   1 
ATOM   614   C CA  . ASP A 1 88  ? -25.405  -40.506 22.312  1.00 47.76  ? 295 ASP A CA  1 
ATOM   615   C C   . ASP A 1 88  ? -25.978  -39.615 23.404  1.00 51.57  ? 295 ASP A C   1 
ATOM   616   O O   . ASP A 1 88  ? -27.154  -39.744 23.772  1.00 50.59  ? 295 ASP A O   1 
ATOM   617   C CB  . ASP A 1 88  ? -26.125  -40.266 20.987  1.00 49.98  ? 295 ASP A CB  1 
ATOM   618   C CG  . ASP A 1 88  ? -25.989  -38.817 20.483  1.00 50.27  ? 295 ASP A CG  1 
ATOM   619   O OD1 . ASP A 1 88  ? -26.683  -37.920 21.017  1.00 45.58  ? 295 ASP A OD1 1 
ATOM   620   O OD2 . ASP A 1 88  ? -25.203  -38.582 19.537  1.00 47.73  ? 295 ASP A OD2 1 
ATOM   621   N N   . VAL A 1 89  ? -25.141  -38.696 23.894  1.00 51.23  ? 296 VAL A N   1 
ATOM   622   C CA  . VAL A 1 89  ? -25.510  -37.774 24.960  1.00 48.87  ? 296 VAL A CA  1 
ATOM   623   C C   . VAL A 1 89  ? -26.742  -36.966 24.588  1.00 53.03  ? 296 VAL A C   1 
ATOM   624   O O   . VAL A 1 89  ? -27.565  -36.642 25.457  1.00 58.65  ? 296 VAL A O   1 
ATOM   625   C CB  . VAL A 1 89  ? -24.316  -36.856 25.310  1.00 55.23  ? 296 VAL A CB  1 
ATOM   626   C CG1 . VAL A 1 89  ? -24.050  -35.799 24.184  1.00 47.28  ? 296 VAL A CG1 1 
ATOM   627   C CG2 . VAL A 1 89  ? -24.536  -36.199 26.666  1.00 50.34  ? 296 VAL A CG2 1 
ATOM   628   N N   . GLN A 1 90  ? -26.919  -36.610 23.320  1.00 50.92  ? 297 GLN A N   1 
ATOM   629   C CA  . GLN A 1 90  ? -28.059  -35.731 22.957  1.00 52.92  ? 297 GLN A CA  1 
ATOM   630   C C   . GLN A 1 90  ? -29.329  -36.579 22.875  1.00 49.75  ? 297 GLN A C   1 
ATOM   631   O O   . GLN A 1 90  ? -30.394  -36.056 23.193  1.00 51.11  ? 297 GLN A O   1 
ATOM   632   C CB  . GLN A 1 90  ? -27.764  -34.978 21.660  1.00 43.80  ? 297 GLN A CB  1 
ATOM   633   C CG  . GLN A 1 90  ? -28.826  -33.963 21.282  1.00 38.83  ? 297 GLN A CG  1 
ATOM   634   C CD  . GLN A 1 90  ? -29.715  -34.500 20.191  1.00 42.98  ? 297 GLN A CD  1 
ATOM   635   O OE1 . GLN A 1 90  ? -29.404  -35.488 19.537  1.00 43.18  ? 297 GLN A OE1 1 
ATOM   636   N NE2 . GLN A 1 90  ? -30.832  -33.837 19.978  1.00 47.04  ? 297 GLN A NE2 1 
ATOM   637   N N   . GLU A 1 91  ? -29.210  -37.845 22.480  1.00 47.18  ? 298 GLU A N   1 
ATOM   638   C CA  . GLU A 1 91  ? -30.402  -38.687 22.473  1.00 49.53  ? 298 GLU A CA  1 
ATOM   639   C C   . GLU A 1 91  ? -30.934  -38.893 23.890  1.00 47.98  ? 298 GLU A C   1 
ATOM   640   O O   . GLU A 1 91  ? -32.144  -38.800 24.138  1.00 44.59  ? 298 GLU A O   1 
ATOM   641   C CB  . GLU A 1 91  ? -30.098  -40.026 21.803  1.00 46.84  ? 298 GLU A CB  1 
ATOM   642   C CG  . GLU A 1 91  ? -31.335  -40.899 21.686  1.00 50.62  ? 298 GLU A CG  1 
ATOM   643   C CD  . GLU A 1 91  ? -31.050  -42.259 21.065  1.00 52.93  ? 298 GLU A CD  1 
ATOM   644   O OE1 . GLU A 1 91  ? -32.027  -43.011 20.829  1.00 50.72  ? 298 GLU A OE1 1 
ATOM   645   O OE2 . GLU A 1 91  ? -29.859  -42.566 20.814  1.00 52.69  ? 298 GLU A OE2 1 
ATOM   646   N N   . LEU A 1 92  ? -30.040  -39.159 24.834  1.00 47.57  ? 299 LEU A N   1 
ATOM   647   C CA  . LEU A 1 92  ? -30.423  -39.229 26.236  1.00 49.82  ? 299 LEU A CA  1 
ATOM   648   C C   . LEU A 1 92  ? -31.149  -37.962 26.675  1.00 49.96  ? 299 LEU A C   1 
ATOM   649   O O   . LEU A 1 92  ? -32.238  -38.021 27.255  1.00 46.27  ? 299 LEU A O   1 
ATOM   650   C CB  . LEU A 1 92  ? -29.158  -39.433 27.071  1.00 52.54  ? 299 LEU A CB  1 
ATOM   651   C CG  . LEU A 1 92  ? -29.389  -39.341 28.559  1.00 50.28  ? 299 LEU A CG  1 
ATOM   652   C CD1 . LEU A 1 92  ? -30.334  -40.451 28.942  1.00 45.15  ? 299 LEU A CD1 1 
ATOM   653   C CD2 . LEU A 1 92  ? -28.078  -39.460 29.265  1.00 55.78  ? 299 LEU A CD2 1 
ATOM   654   N N   . CYS A 1 93  ? -30.539  -36.798 26.433  1.00 50.67  ? 300 CYS A N   1 
ATOM   655   C CA  . CYS A 1 93  ? -31.114  -35.485 26.840  1.00 44.12  ? 300 CYS A CA  1 
ATOM   656   C C   . CYS A 1 93  ? -32.506  -35.323 26.262  1.00 47.00  ? 300 CYS A C   1 
ATOM   657   O O   . CYS A 1 93  ? -33.388  -34.906 26.997  1.00 52.66  ? 300 CYS A O   1 
ATOM   658   C CB  . CYS A 1 93  ? -30.262  -34.326 26.340  1.00 52.27  ? 300 CYS A CB  1 
ATOM   659   S SG  . CYS A 1 93  ? -30.835  -32.692 26.859  1.00 48.96  ? 300 CYS A SG  1 
ATOM   660   N N   . ARG A 1 94  ? -32.676  -35.620 24.981  1.00 48.13  ? 301 ARG A N   1 
ATOM   661   C CA  . ARG A 1 94  ? -34.023  -35.579 24.440  1.00 42.80  ? 301 ARG A CA  1 
ATOM   662   C C   . ARG A 1 94  ? -34.945  -36.527 25.202  1.00 44.55  ? 301 ARG A C   1 
ATOM   663   O O   . ARG A 1 94  ? -36.018  -36.138 25.684  1.00 48.93  ? 301 ARG A O   1 
ATOM   664   C CB  . ARG A 1 94  ? -33.994  -35.919 22.953  1.00 39.27  ? 301 ARG A CB  1 
ATOM   665   C CG  . ARG A 1 94  ? -33.257  -34.897 22.071  1.00 44.91  ? 301 ARG A CG  1 
ATOM   666   C CD  . ARG A 1 94  ? -34.142  -33.694 21.727  1.00 39.35  ? 301 ARG A CD  1 
ATOM   667   N NE  . ARG A 1 94  ? -34.456  -32.951 22.938  1.00 43.57  ? 301 ARG A NE  1 
ATOM   668   C CZ  . ARG A 1 94  ? -33.671  -32.039 23.495  1.00 41.88  ? 301 ARG A CZ  1 
ATOM   669   N NH1 . ARG A 1 94  ? -32.515  -31.704 22.941  1.00 39.43  ? 301 ARG A NH1 1 
ATOM   670   N NH2 . ARG A 1 94  ? -34.053  -31.463 24.615  1.00 44.58  ? 301 ARG A NH2 1 
ATOM   671   N N   . VAL A 1 95  ? -34.532  -37.779 25.347  1.00 43.11  ? 302 VAL A N   1 
ATOM   672   C CA  . VAL A 1 95  ? -35.374  -38.726 26.063  1.00 43.93  ? 302 VAL A CA  1 
ATOM   673   C C   . VAL A 1 95  ? -35.563  -38.303 27.525  1.00 43.66  ? 302 VAL A C   1 
ATOM   674   O O   . VAL A 1 95  ? -36.687  -38.276 28.030  1.00 46.92  ? 302 VAL A O   1 
ATOM   675   C CB  . VAL A 1 95  ? -34.811  -40.144 25.928  1.00 37.39  ? 302 VAL A CB  1 
ATOM   676   C CG1 . VAL A 1 95  ? -35.559  -41.075 26.822  1.00 41.72  ? 302 VAL A CG1 1 
ATOM   677   C CG2 . VAL A 1 95  ? -34.997  -40.591 24.513  1.00 42.61  ? 302 VAL A CG2 1 
ATOM   678   N N   . LEU A 1 96  ? -34.486  -37.925 28.215  1.00 42.85  ? 303 LEU A N   1 
ATOM   679   C CA  . LEU A 1 96  ? -34.585  -37.670 29.653  1.00 42.43  ? 303 LEU A CA  1 
ATOM   680   C C   . LEU A 1 96  ? -35.393  -36.407 29.946  1.00 46.52  ? 303 LEU A C   1 
ATOM   681   O O   . LEU A 1 96  ? -36.352  -36.440 30.722  1.00 48.78  ? 303 LEU A O   1 
ATOM   682   C CB  . LEU A 1 96  ? -33.184  -37.590 30.252  1.00 48.69  ? 303 LEU A CB  1 
ATOM   683   C CG  . LEU A 1 96  ? -32.841  -37.558 31.745  1.00 47.84  ? 303 LEU A CG  1 
ATOM   684   C CD1 . LEU A 1 96  ? -32.812  -36.137 32.257  1.00 51.99  ? 303 LEU A CD1 1 
ATOM   685   C CD2 . LEU A 1 96  ? -33.815  -38.394 32.493  1.00 43.39  ? 303 LEU A CD2 1 
ATOM   686   N N   . LEU A 1 97  ? -35.059  -35.304 29.296  1.00 43.31  ? 304 LEU A N   1 
ATOM   687   C CA  . LEU A 1 97  ? -35.767  -34.036 29.592  1.00 44.16  ? 304 LEU A CA  1 
ATOM   688   C C   . LEU A 1 97  ? -37.237  -34.148 29.173  1.00 46.23  ? 304 LEU A C   1 
ATOM   689   O O   . LEU A 1 97  ? -38.047  -33.499 29.825  1.00 54.19  ? 304 LEU A O   1 
ATOM   690   C CB  . LEU A 1 97  ? -35.048  -32.875 28.901  1.00 44.71  ? 304 LEU A CB  1 
ATOM   691   C CG  . LEU A 1 97  ? -33.977  -32.170 29.725  1.00 42.09  ? 304 LEU A CG  1 
ATOM   692   C CD1 . LEU A 1 97  ? -33.550  -30.889 29.038  1.00 42.56  ? 304 LEU A CD1 1 
ATOM   693   C CD2 . LEU A 1 97  ? -34.477  -31.877 31.128  1.00 39.18  ? 304 LEU A CD2 1 
ATOM   694   N N   . ASP A 1 98  ? -37.570  -34.925 28.136  1.00 49.95  ? 305 ASP A N   1 
ATOM   695   C CA  . ASP A 1 98  ? -38.974  -35.135 27.799  1.00 46.26  ? 305 ASP A CA  1 
ATOM   696   C C   . ASP A 1 98  ? -39.673  -35.909 28.896  1.00 45.58  ? 305 ASP A C   1 
ATOM   697   O O   . ASP A 1 98  ? -40.813  -35.611 29.251  1.00 50.05  ? 305 ASP A O   1 
ATOM   698   C CB  . ASP A 1 98  ? -39.118  -35.882 26.478  1.00 43.72  ? 305 ASP A CB  1 
ATOM   699   C CG  . ASP A 1 98  ? -40.566  -36.266 26.190  1.00 53.77  ? 305 ASP A CG  1 
ATOM   700   O OD1 . ASP A 1 98  ? -41.427  -35.359 26.174  1.00 54.21  ? 305 ASP A OD1 1 
ATOM   701   O OD2 . ASP A 1 98  ? -40.854  -37.468 25.992  1.00 58.11  ? 305 ASP A OD2 1 
ATOM   702   N N   . ASN A 1 99  ? -38.996  -36.907 29.444  1.00 44.19  ? 306 ASN A N   1 
ATOM   703   C CA  . ASN A 1 99  ? -39.533  -37.646 30.572  1.00 46.62  ? 306 ASN A CA  1 
ATOM   704   C C   . ASN A 1 99  ? -39.866  -36.697 31.715  1.00 46.82  ? 306 ASN A C   1 
ATOM   705   O O   . ASN A 1 99  ? -41.013  -36.604 32.158  1.00 48.97  ? 306 ASN A O   1 
ATOM   706   C CB  . ASN A 1 99  ? -38.511  -38.707 30.982  1.00 43.44  ? 306 ASN A CB  1 
ATOM   707   C CG  . ASN A 1 99  ? -38.984  -39.592 32.109  1.00 59.78  ? 306 ASN A CG  1 
ATOM   708   O OD1 . ASN A 1 99  ? -39.426  -39.110 33.152  1.00 61.22  ? 306 ASN A OD1 1 
ATOM   709   N ND2 . ASN A 1 99  ? -38.871  -40.911 31.915  1.00 65.09  ? 306 ASN A ND2 1 
ATOM   710   N N   . VAL A 1 100 ? -38.874  -35.949 32.174  1.00 43.91  ? 307 VAL A N   1 
ATOM   711   C CA  . VAL A 1 100 ? -39.071  -35.106 33.339  1.00 46.47  ? 307 VAL A CA  1 
ATOM   712   C C   . VAL A 1 100 ? -40.117  -34.040 33.054  1.00 51.77  ? 307 VAL A C   1 
ATOM   713   O O   . VAL A 1 100 ? -40.931  -33.705 33.922  1.00 50.49  ? 307 VAL A O   1 
ATOM   714   C CB  . VAL A 1 100 ? -37.725  -34.500 33.770  1.00 51.42  ? 307 VAL A CB  1 
ATOM   715   C CG1 . VAL A 1 100 ? -37.903  -33.612 34.974  1.00 48.95  ? 307 VAL A CG1 1 
ATOM   716   C CG2 . VAL A 1 100 ? -36.742  -35.610 34.081  1.00 52.72  ? 307 VAL A CG2 1 
ATOM   717   N N   . GLU A 1 101 ? -40.133  -33.503 31.831  1.00 49.69  ? 308 GLU A N   1 
ATOM   718   C CA  . GLU A 1 101 ? -41.092  -32.451 31.511  1.00 49.55  ? 308 GLU A CA  1 
ATOM   719   C C   . GLU A 1 101 ? -42.527  -32.880 31.807  1.00 59.86  ? 308 GLU A C   1 
ATOM   720   O O   . GLU A 1 101 ? -43.292  -32.141 32.446  1.00 64.67  ? 308 GLU A O   1 
ATOM   721   C CB  . GLU A 1 101 ? -40.977  -32.045 30.053  1.00 46.94  ? 308 GLU A CB  1 
ATOM   722   C CG  . GLU A 1 101 ? -42.058  -31.054 29.738  1.00 47.11  ? 308 GLU A CG  1 
ATOM   723   C CD  . GLU A 1 101 ? -41.819  -30.293 28.475  1.00 56.24  ? 308 GLU A CD  1 
ATOM   724   O OE1 . GLU A 1 101 ? -42.684  -29.461 28.142  1.00 61.58  ? 308 GLU A OE1 1 
ATOM   725   O OE2 . GLU A 1 101 ? -40.781  -30.524 27.806  1.00 57.21  ? 308 GLU A OE2 1 
ATOM   726   N N   . ASN A 1 102 ? -42.892  -34.078 31.360  1.00 57.69  ? 309 ASN A N   1 
ATOM   727   C CA  . ASN A 1 102 ? -44.264  -34.593 31.587  1.00 62.08  ? 309 ASN A CA  1 
ATOM   728   C C   . ASN A 1 102 ? -44.424  -34.988 33.055  1.00 61.62  ? 309 ASN A C   1 
ATOM   729   O O   . ASN A 1 102 ? -45.522  -34.792 33.587  1.00 63.44  ? 309 ASN A O   1 
ATOM   730   C CB  . ASN A 1 102 ? -44.594  -35.748 30.642  1.00 66.85  ? 309 ASN A CB  1 
ATOM   731   C CG  . ASN A 1 102 ? -44.323  -35.431 29.188  1.00 77.12  ? 309 ASN A CG  1 
ATOM   732   O OD1 . ASN A 1 102 ? -44.497  -34.299 28.747  1.00 74.48  ? 309 ASN A OD1 1 
ATOM   733   N ND2 . ASN A 1 102 ? -43.897  -36.430 28.435  1.00 84.57  ? 309 ASN A ND2 1 
ATOM   734   N N   . LYS A 1 103 ? -43.380  -35.535 33.681  1.00 56.19  ? 310 LYS A N   1 
ATOM   735   C CA  . LYS A 1 103 ? -43.475  -35.837 35.104  1.00 57.08  ? 310 LYS A CA  1 
ATOM   736   C C   . LYS A 1 103 ? -43.630  -34.579 35.963  1.00 54.12  ? 310 LYS A C   1 
ATOM   737   O O   . LYS A 1 103 ? -43.941  -34.704 37.147  1.00 52.68  ? 310 LYS A O   1 
ATOM   738   C CB  . LYS A 1 103 ? -42.257  -36.650 35.539  1.00 54.56  ? 310 LYS A CB  1 
ATOM   739   N N   . MET A 1 104 ? -43.445  -33.381 35.403  1.00 54.60  ? 311 MET A N   1 
ATOM   740   C CA  . MET A 1 104 ? -43.567  -32.129 36.143  1.00 57.45  ? 311 MET A CA  1 
ATOM   741   C C   . MET A 1 104 ? -44.924  -31.461 35.958  1.00 62.02  ? 311 MET A C   1 
ATOM   742   O O   . MET A 1 104 ? -45.137  -30.350 36.466  1.00 60.78  ? 311 MET A O   1 
ATOM   743   C CB  . MET A 1 104 ? -42.472  -31.149 35.715  1.00 53.79  ? 311 MET A CB  1 
ATOM   744   C CG  . MET A 1 104 ? -41.143  -31.306 36.400  1.00 51.10  ? 311 MET A CG  1 
ATOM   745   S SD  . MET A 1 104 ? -40.160  -29.811 36.108  1.00 64.54  ? 311 MET A SD  1 
ATOM   746   C CE  . MET A 1 104 ? -38.634  -30.181 36.956  1.00 53.84  ? 311 MET A CE  1 
ATOM   747   N N   . LYS A 1 105 ? -45.831  -32.091 35.220  1.00 65.86  ? 312 LYS A N   1 
ATOM   748   C CA  . LYS A 1 105 ? -47.125  -31.495 34.928  1.00 63.36  ? 312 LYS A CA  1 
ATOM   749   C C   . LYS A 1 105 ? -48.067  -31.720 36.097  1.00 61.44  ? 312 LYS A C   1 
ATOM   750   O O   . LYS A 1 105 ? -48.089  -32.797 36.706  1.00 62.81  ? 312 LYS A O   1 
ATOM   751   C CB  . LYS A 1 105 ? -47.715  -32.084 33.642  1.00 59.05  ? 312 LYS A CB  1 
ATOM   752   N N   . GLY A 1 106 ? -48.820  -30.693 36.470  1.00 62.79  ? 313 GLY A N   1 
ATOM   753   C CA  . GLY A 1 106 ? -49.772  -30.826 37.589  1.00 70.73  ? 313 GLY A CA  1 
ATOM   754   C C   . GLY A 1 106 ? -49.109  -30.641 38.935  1.00 74.28  ? 313 GLY A C   1 
ATOM   755   O O   . GLY A 1 106 ? -49.806  -30.792 39.949  1.00 81.62  ? 313 GLY A O   1 
ATOM   756   N N   . THR A 1 107 ? -47.810  -30.355 38.949  1.00 67.32  ? 314 THR A N   1 
ATOM   757   C CA  . THR A 1 107 ? -47.056  -30.110 40.169  1.00 57.96  ? 314 THR A CA  1 
ATOM   758   C C   . THR A 1 107 ? -46.627  -28.649 40.194  1.00 60.58  ? 314 THR A C   1 
ATOM   759   O O   . THR A 1 107 ? -46.737  -27.930 39.197  1.00 62.70  ? 314 THR A O   1 
ATOM   760   C CB  . THR A 1 107 ? -45.828  -31.017 40.254  1.00 55.90  ? 314 THR A CB  1 
ATOM   761   O OG1 . THR A 1 107 ? -44.797  -30.460 39.440  1.00 55.22  ? 314 THR A OG1 1 
ATOM   762   C CG2 . THR A 1 107 ? -46.141  -32.396 39.756  1.00 50.21  ? 314 THR A CG2 1 
ATOM   763   N N   . CYS A 1 108 ? -46.119  -28.203 41.346  1.00 62.25  ? 315 CYS A N   1 
ATOM   764   C CA  . CYS A 1 108 ? -45.795  -26.787 41.499  1.00 58.35  ? 315 CYS A CA  1 
ATOM   765   C C   . CYS A 1 108 ? -44.743  -26.309 40.512  1.00 61.16  ? 315 CYS A C   1 
ATOM   766   O O   . CYS A 1 108 ? -44.485  -25.105 40.448  1.00 69.42  ? 315 CYS A O   1 
ATOM   767   C CB  . CYS A 1 108 ? -45.319  -26.494 42.922  1.00 62.88  ? 315 CYS A CB  1 
ATOM   768   S SG  . CYS A 1 108 ? -43.893  -27.458 43.484  1.00 79.42  ? 315 CYS A SG  1 
ATOM   769   N N   . VAL A 1 109 ? -44.128  -27.246 39.787  1.00 64.68  ? 316 VAL A N   1 
ATOM   770   C CA  . VAL A 1 109 ? -42.984  -26.900 38.896  1.00 62.53  ? 316 VAL A CA  1 
ATOM   771   C C   . VAL A 1 109 ? -43.329  -27.151 37.425  1.00 63.75  ? 316 VAL A C   1 
ATOM   772   O O   . VAL A 1 109 ? -42.408  -27.372 36.643  1.00 58.62  ? 316 VAL A O   1 
ATOM   773   C CB  . VAL A 1 109 ? -41.718  -27.661 39.335  1.00 54.92  ? 316 VAL A CB  1 
ATOM   774   C CG1 . VAL A 1 109 ? -41.027  -26.969 40.495  1.00 58.80  ? 316 VAL A CG1 1 
ATOM   775   C CG2 . VAL A 1 109 ? -41.986  -29.112 39.680  1.00 51.44  ? 316 VAL A CG2 1 
ATOM   776   N N   . GLU A 1 110 ? -44.604  -27.085 37.050  1.00 65.64  ? 317 GLU A N   1 
ATOM   777   C CA  . GLU A 1 110 ? -44.958  -27.206 35.648  1.00 59.81  ? 317 GLU A CA  1 
ATOM   778   C C   . GLU A 1 110 ? -44.407  -26.035 34.866  1.00 54.28  ? 317 GLU A C   1 
ATOM   779   O O   . GLU A 1 110 ? -44.413  -24.898 35.338  1.00 54.55  ? 317 GLU A O   1 
ATOM   780   C CB  . GLU A 1 110 ? -46.463  -27.265 35.475  1.00 58.47  ? 317 GLU A CB  1 
ATOM   781   C CG  . GLU A 1 110 ? -46.874  -27.780 34.136  1.00 59.94  ? 317 GLU A CG  1 
ATOM   782   C CD  . GLU A 1 110 ? -48.372  -27.806 33.985  1.00 65.71  ? 317 GLU A CD  1 
ATOM   783   O OE1 . GLU A 1 110 ? -48.869  -27.131 33.060  1.00 67.16  ? 317 GLU A OE1 1 
ATOM   784   O OE2 . GLU A 1 110 ? -49.045  -28.491 34.800  1.00 62.99  ? 317 GLU A OE2 1 
ATOM   785   N N   . GLY A 1 111 ? -43.912  -26.330 33.674  1.00 54.15  ? 318 GLY A N   1 
ATOM   786   C CA  . GLY A 1 111 ? -43.436  -25.325 32.756  1.00 45.87  ? 318 GLY A CA  1 
ATOM   787   C C   . GLY A 1 111 ? -41.952  -25.080 32.809  1.00 50.88  ? 318 GLY A C   1 
ATOM   788   O O   . GLY A 1 111 ? -41.445  -24.285 32.000  1.00 50.55  ? 318 GLY A O   1 
ATOM   789   N N   . THR A 1 112 ? -41.240  -25.736 33.734  1.00 51.76  ? 319 THR A N   1 
ATOM   790   C CA  . THR A 1 112 ? -39.844  -25.398 33.981  1.00 51.48  ? 319 THR A CA  1 
ATOM   791   C C   . THR A 1 112 ? -38.984  -25.724 32.769  1.00 53.45  ? 319 THR A C   1 
ATOM   792   O O   . THR A 1 112 ? -38.308  -24.844 32.215  1.00 47.84  ? 319 THR A O   1 
ATOM   793   C CB  . THR A 1 112 ? -39.305  -26.139 35.210  1.00 46.08  ? 319 THR A CB  1 
ATOM   794   O OG1 . THR A 1 112 ? -40.203  -26.012 36.314  1.00 48.12  ? 319 THR A OG1 1 
ATOM   795   C CG2 . THR A 1 112 ? -37.977  -25.538 35.609  1.00 44.03  ? 319 THR A CG2 1 
ATOM   796   N N   . ILE A 1 113 ? -38.983  -26.997 32.361  1.00 52.64  ? 320 ILE A N   1 
ATOM   797   C CA  . ILE A 1 113 ? -38.133  -27.404 31.252  1.00 52.00  ? 320 ILE A CA  1 
ATOM   798   C C   . ILE A 1 113 ? -38.415  -26.593 29.991  1.00 50.77  ? 320 ILE A C   1 
ATOM   799   O O   . ILE A 1 113 ? -37.464  -26.062 29.406  1.00 50.12  ? 320 ILE A O   1 
ATOM   800   C CB  . ILE A 1 113 ? -38.250  -28.938 31.036  1.00 49.87  ? 320 ILE A CB  1 
ATOM   801   C CG1 . ILE A 1 113 ? -37.564  -29.661 32.185  1.00 49.49  ? 320 ILE A CG1 1 
ATOM   802   C CG2 . ILE A 1 113 ? -37.689  -29.373 29.696  1.00 48.71  ? 320 ILE A CG2 1 
ATOM   803   C CD1 . ILE A 1 113 ? -38.510  -30.567 32.939  1.00 59.15  ? 320 ILE A CD1 1 
ATOM   804   N N   . PRO A 1 114 ? -39.669  -26.391 29.574  1.00 50.59  ? 321 PRO A N   1 
ATOM   805   C CA  . PRO A 1 114 ? -39.870  -25.473 28.443  1.00 48.98  ? 321 PRO A CA  1 
ATOM   806   C C   . PRO A 1 114 ? -39.478  -24.037 28.758  1.00 46.28  ? 321 PRO A C   1 
ATOM   807   O O   . PRO A 1 114 ? -38.981  -23.351 27.858  1.00 52.26  ? 321 PRO A O   1 
ATOM   808   C CB  . PRO A 1 114 ? -41.366  -25.618 28.101  1.00 44.67  ? 321 PRO A CB  1 
ATOM   809   C CG  . PRO A 1 114 ? -41.957  -26.421 29.154  1.00 48.36  ? 321 PRO A CG  1 
ATOM   810   C CD  . PRO A 1 114 ? -40.888  -27.154 29.886  1.00 50.55  ? 321 PRO A CD  1 
ATOM   811   N N   . LYS A 1 115 ? -39.638  -23.551 29.992  1.00 43.37  ? 322 LYS A N   1 
ATOM   812   C CA  . LYS A 1 115 ? -39.260  -22.159 30.231  1.00 42.42  ? 322 LYS A CA  1 
ATOM   813   C C   . LYS A 1 115 ? -37.751  -21.971 30.136  1.00 46.27  ? 322 LYS A C   1 
ATOM   814   O O   . LYS A 1 115 ? -37.283  -20.908 29.719  1.00 50.57  ? 322 LYS A O   1 
ATOM   815   C CB  . LYS A 1 115 ? -39.786  -21.681 31.585  1.00 42.01  ? 322 LYS A CB  1 
ATOM   816   N N   . LEU A 1 116 ? -36.981  -22.999 30.490  1.00 48.00  ? 323 LEU A N   1 
ATOM   817   C CA  . LEU A 1 116 ? -35.526  -22.941 30.435  1.00 49.74  ? 323 LEU A CA  1 
ATOM   818   C C   . LEU A 1 116 ? -35.004  -23.188 29.034  1.00 53.06  ? 323 LEU A C   1 
ATOM   819   O O   . LEU A 1 116 ? -34.038  -22.535 28.605  1.00 51.29  ? 323 LEU A O   1 
ATOM   820   C CB  . LEU A 1 116 ? -34.905  -24.000 31.362  1.00 48.27  ? 323 LEU A CB  1 
ATOM   821   C CG  . LEU A 1 116 ? -34.907  -23.725 32.855  1.00 47.81  ? 323 LEU A CG  1 
ATOM   822   C CD1 . LEU A 1 116 ? -34.359  -24.910 33.602  1.00 48.89  ? 323 LEU A CD1 1 
ATOM   823   C CD2 . LEU A 1 116 ? -34.094  -22.477 33.146  1.00 50.29  ? 323 LEU A CD2 1 
ATOM   824   N N   . PHE A 1 117 ? -35.597  -24.169 28.331  1.00 48.92  ? 324 PHE A N   1 
ATOM   825   C CA  . PHE A 1 117 ? -34.960  -24.738 27.155  1.00 46.88  ? 324 PHE A CA  1 
ATOM   826   C C   . PHE A 1 117 ? -35.718  -24.567 25.852  1.00 46.08  ? 324 PHE A C   1 
ATOM   827   O O   . PHE A 1 117 ? -35.141  -24.865 24.806  1.00 53.12  ? 324 PHE A O   1 
ATOM   828   C CB  . PHE A 1 117 ? -34.712  -26.241 27.334  1.00 40.36  ? 324 PHE A CB  1 
ATOM   829   C CG  . PHE A 1 117 ? -33.828  -26.608 28.509  1.00 45.60  ? 324 PHE A CG  1 
ATOM   830   C CD1 . PHE A 1 117 ? -32.452  -26.533 28.417  1.00 49.00  ? 324 PHE A CD1 1 
ATOM   831   C CD2 . PHE A 1 117 ? -34.378  -27.106 29.682  1.00 45.16  ? 324 PHE A CD2 1 
ATOM   832   C CE1 . PHE A 1 117 ? -31.643  -26.926 29.478  1.00 44.30  ? 324 PHE A CE1 1 
ATOM   833   C CE2 . PHE A 1 117 ? -33.574  -27.488 30.746  1.00 45.97  ? 324 PHE A CE2 1 
ATOM   834   C CZ  . PHE A 1 117 ? -32.207  -27.401 30.640  1.00 43.48  ? 324 PHE A CZ  1 
ATOM   835   N N   . ARG A 1 118 ? -36.969  -24.120 25.857  1.00 42.95  ? 325 ARG A N   1 
ATOM   836   C CA  . ARG A 1 118 ? -37.806  -24.200 24.663  1.00 42.06  ? 325 ARG A CA  1 
ATOM   837   C C   . ARG A 1 118 ? -37.874  -22.861 23.956  1.00 41.35  ? 325 ARG A C   1 
ATOM   838   O O   . ARG A 1 118 ? -38.260  -21.858 24.558  1.00 48.97  ? 325 ARG A O   1 
ATOM   839   C CB  . ARG A 1 118 ? -39.222  -24.663 24.996  1.00 49.52  ? 325 ARG A CB  1 
ATOM   840   C CG  . ARG A 1 118 ? -40.143  -24.734 23.781  1.00 54.23  ? 325 ARG A CG  1 
ATOM   841   C CD  . ARG A 1 118 ? -41.405  -23.901 23.978  1.00 55.59  ? 325 ARG A CD  1 
ATOM   842   N NE  . ARG A 1 118 ? -42.529  -24.735 24.413  1.00 58.47  ? 325 ARG A NE  1 
ATOM   843   C CZ  . ARG A 1 118 ? -43.565  -24.274 25.110  1.00 64.13  ? 325 ARG A CZ  1 
ATOM   844   N NH1 . ARG A 1 118 ? -43.608  -22.988 25.441  1.00 69.73  ? 325 ARG A NH1 1 
ATOM   845   N NH2 . ARG A 1 118 ? -44.553  -25.088 25.480  1.00 63.18  ? 325 ARG A NH2 1 
ATOM   846   N N   . GLY A 1 119 ? -37.510  -22.854 22.674  1.00 46.42  ? 326 GLY A N   1 
ATOM   847   C CA  . GLY A 1 119 ? -37.631  -21.687 21.830  1.00 47.67  ? 326 GLY A CA  1 
ATOM   848   C C   . GLY A 1 119 ? -38.570  -21.976 20.670  1.00 47.33  ? 326 GLY A C   1 
ATOM   849   O O   . GLY A 1 119 ? -39.093  -23.087 20.538  1.00 47.23  ? 326 GLY A O   1 
ATOM   850   N N   . LYS A 1 120 ? -38.858  -20.943 19.877  1.00 41.71  ? 327 LYS A N   1 
ATOM   851   C CA  . LYS A 1 120 ? -39.748  -21.095 18.699  1.00 46.46  ? 327 LYS A CA  1 
ATOM   852   C C   . LYS A 1 120 ? -39.065  -20.575 17.438  1.00 46.12  ? 327 LYS A C   1 
ATOM   853   O O   . LYS A 1 120 ? -38.368  -19.564 17.520  1.00 47.52  ? 327 LYS A O   1 
ATOM   854   C CB  . LYS A 1 120 ? -41.062  -20.337 18.875  1.00 42.15  ? 327 LYS A CB  1 
ATOM   855   C CG  . LYS A 1 120 ? -42.141  -20.669 17.855  1.00 49.72  ? 327 LYS A CG  1 
ATOM   856   C CD  . LYS A 1 120 ? -43.537  -20.547 18.400  1.00 44.94  ? 327 LYS A CD  1 
ATOM   857   C CE  . LYS A 1 120 ? -44.312  -21.841 18.310  1.00 48.90  ? 327 LYS A CE  1 
ATOM   858   N NZ  . LYS A 1 120 ? -45.029  -22.130 19.573  1.00 48.85  ? 327 LYS A NZ  1 
ATOM   859   N N   . MET A 1 121 ? -39.264  -21.269 16.320  1.00 43.02  ? 328 MET A N   1 
ATOM   860   C CA  . MET A 1 121 ? -38.710  -20.804 15.029  1.00 47.60  ? 328 MET A CA  1 
ATOM   861   C C   . MET A 1 121 ? -39.820  -20.624 13.993  1.00 50.26  ? 328 MET A C   1 
ATOM   862   O O   . MET A 1 121 ? -40.890  -21.206 14.168  1.00 50.34  ? 328 MET A O   1 
ATOM   863   C CB  . MET A 1 121 ? -37.643  -21.771 14.507  1.00 49.01  ? 328 MET A CB  1 
ATOM   864   C CG  . MET A 1 121 ? -38.147  -23.156 14.184  1.00 56.03  ? 328 MET A CG  1 
ATOM   865   S SD  . MET A 1 121 ? -36.797  -24.349 14.075  1.00 69.62  ? 328 MET A SD  1 
ATOM   866   C CE  . MET A 1 121 ? -37.589  -25.790 14.783  1.00 52.93  ? 328 MET A CE  1 
ATOM   867   N N   . VAL A 1 122 ? -39.558  -19.841 12.965  1.00 44.78  ? 329 VAL A N   1 
ATOM   868   C CA  . VAL A 1 122 ? -40.583  -19.652 11.912  1.00 45.16  ? 329 VAL A CA  1 
ATOM   869   C C   . VAL A 1 122 ? -40.007  -20.097 10.567  1.00 45.90  ? 329 VAL A C   1 
ATOM   870   O O   . VAL A 1 122 ? -38.832  -19.852 10.319  1.00 45.34  ? 329 VAL A O   1 
ATOM   871   C CB  . VAL A 1 122 ? -41.111  -18.208 11.938  1.00 51.25  ? 329 VAL A CB  1 
ATOM   872   C CG1 . VAL A 1 122 ? -40.017  -17.170 11.778  1.00 45.51  ? 329 VAL A CG1 1 
ATOM   873   C CG2 . VAL A 1 122 ? -42.287  -17.997 11.006  1.00 51.58  ? 329 VAL A CG2 1 
ATOM   874   N N   . SER A 1 123 ? -40.782  -20.859 9.800   1.00 49.11  ? 330 SER A N   1 
ATOM   875   C CA  . SER A 1 123 ? -40.349  -21.262 8.441   1.00 49.69  ? 330 SER A CA  1 
ATOM   876   C C   . SER A 1 123 ? -41.196  -20.508 7.422   1.00 53.39  ? 330 SER A C   1 
ATOM   877   O O   . SER A 1 123 ? -42.423  -20.588 7.494   1.00 54.37  ? 330 SER A O   1 
ATOM   878   C CB  . SER A 1 123 ? -40.411  -22.744 8.217   1.00 50.59  ? 330 SER A CB  1 
ATOM   879   O OG  . SER A 1 123 ? -39.383  -23.409 8.929   1.00 59.90  ? 330 SER A OG  1 
ATOM   880   N N   . TYR A 1 124 ? -40.538  -19.791 6.526   1.00 59.73  ? 331 TYR A N   1 
ATOM   881   C CA  . TYR A 1 124 ? -41.221  -18.997 5.478   1.00 59.65  ? 331 TYR A CA  1 
ATOM   882   C C   . TYR A 1 124 ? -41.029  -19.644 4.109   1.00 51.33  ? 331 TYR A C   1 
ATOM   883   O O   . TYR A 1 124 ? -39.891  -19.844 3.715   1.00 55.15  ? 331 TYR A O   1 
ATOM   884   C CB  . TYR A 1 124 ? -40.666  -17.575 5.474   1.00 57.16  ? 331 TYR A CB  1 
ATOM   885   C CG  . TYR A 1 124 ? -40.857  -16.791 6.746   1.00 65.35  ? 331 TYR A CG  1 
ATOM   886   C CD1 . TYR A 1 124 ? -42.122  -16.478 7.206   1.00 62.75  ? 331 TYR A CD1 1 
ATOM   887   C CD2 . TYR A 1 124 ? -39.772  -16.335 7.474   1.00 62.33  ? 331 TYR A CD2 1 
ATOM   888   C CE1 . TYR A 1 124 ? -42.311  -15.744 8.363   1.00 61.32  ? 331 TYR A CE1 1 
ATOM   889   C CE2 . TYR A 1 124 ? -39.942  -15.599 8.633   1.00 58.54  ? 331 TYR A CE2 1 
ATOM   890   C CZ  . TYR A 1 124 ? -41.216  -15.300 9.077   1.00 57.28  ? 331 TYR A CZ  1 
ATOM   891   O OH  . TYR A 1 124 ? -41.399  -14.578 10.218  1.00 51.44  ? 331 TYR A OH  1 
ATOM   892   N N   . ILE A 1 125 ? -42.120  -19.918 3.404   1.00 51.15  ? 332 ILE A N   1 
ATOM   893   C CA  . ILE A 1 125 ? -42.111  -20.556 2.092   1.00 49.98  ? 332 ILE A CA  1 
ATOM   894   C C   . ILE A 1 125 ? -42.883  -19.692 1.116   1.00 54.35  ? 332 ILE A C   1 
ATOM   895   O O   . ILE A 1 125 ? -44.091  -19.493 1.304   1.00 54.42  ? 332 ILE A O   1 
ATOM   896   C CB  . ILE A 1 125 ? -42.765  -21.938 2.137   1.00 47.79  ? 332 ILE A CB  1 
ATOM   897   C CG1 . ILE A 1 125 ? -42.067  -22.839 3.143   1.00 49.06  ? 332 ILE A CG1 1 
ATOM   898   C CG2 . ILE A 1 125 ? -42.765  -22.539 0.758   1.00 50.20  ? 332 ILE A CG2 1 
ATOM   899   C CD1 . ILE A 1 125 ? -42.895  -24.047 3.485   1.00 48.62  ? 332 ILE A CD1 1 
ATOM   900   N N   . GLN A 1 126 ? -42.221  -19.265 0.032   1.00 55.52  ? 333 GLN A N   1 
ATOM   901   C CA  . GLN A 1 126 ? -42.832  -18.452 -1.022  1.00 59.27  ? 333 GLN A CA  1 
ATOM   902   C C   . GLN A 1 126 ? -42.542  -19.014 -2.420  1.00 57.53  ? 333 GLN A C   1 
ATOM   903   O O   . GLN A 1 126 ? -41.386  -19.279 -2.766  1.00 56.49  ? 333 GLN A O   1 
ATOM   904   C CB  . GLN A 1 126 ? -42.336  -17.006 -0.891  1.00 58.94  ? 333 GLN A CB  1 
ATOM   905   C CG  . GLN A 1 126 ? -42.936  -15.967 -1.806  1.00 57.85  ? 333 GLN A CG  1 
ATOM   906   C CD  . GLN A 1 126 ? -41.944  -14.834 -1.974  1.00 70.90  ? 333 GLN A CD  1 
ATOM   907   O OE1 . GLN A 1 126 ? -40.784  -15.074 -2.312  1.00 74.78  ? 333 GLN A OE1 1 
ATOM   908   N NE2 . GLN A 1 126 ? -42.371  -13.605 -1.698  1.00 71.67  ? 333 GLN A NE2 1 
ATOM   909   N N   . CYS A 1 127 ? -43.592  -19.203 -3.221  1.00 54.84  ? 334 CYS A N   1 
ATOM   910   C CA  . CYS A 1 127 ? -43.420  -19.729 -4.572  1.00 48.37  ? 334 CYS A CA  1 
ATOM   911   C C   . CYS A 1 127 ? -42.745  -18.728 -5.502  1.00 53.93  ? 334 CYS A C   1 
ATOM   912   O O   . CYS A 1 127 ? -42.940  -17.512 -5.408  1.00 58.47  ? 334 CYS A O   1 
ATOM   913   C CB  . CYS A 1 127 ? -44.761  -20.134 -5.151  1.00 47.30  ? 334 CYS A CB  1 
ATOM   914   S SG  . CYS A 1 127 ? -45.482  -21.510 -4.260  1.00 56.23  ? 334 CYS A SG  1 
ATOM   915   N N   . LYS A 1 128 ? -41.972  -19.234 -6.442  1.00 53.59  ? 335 LYS A N   1 
ATOM   916   C CA  . LYS A 1 128 ? -41.189  -18.304 -7.279  1.00 59.20  ? 335 LYS A CA  1 
ATOM   917   C C   . LYS A 1 128 ? -41.950  -17.919 -8.544  1.00 67.09  ? 335 LYS A C   1 
ATOM   918   O O   . LYS A 1 128 ? -41.677  -16.827 -9.061  1.00 72.29  ? 335 LYS A O   1 
ATOM   919   C CB  . LYS A 1 128 ? -39.860  -18.980 -7.608  1.00 57.87  ? 335 LYS A CB  1 
ATOM   920   C CG  . LYS A 1 128 ? -39.000  -19.321 -6.405  1.00 63.61  ? 335 LYS A CG  1 
ATOM   921   C CD  . LYS A 1 128 ? -37.676  -19.905 -6.807  1.00 64.48  ? 335 LYS A CD  1 
ATOM   922   C CE  . LYS A 1 128 ? -36.781  -18.897 -7.492  1.00 66.50  ? 335 LYS A CE  1 
ATOM   923   N NZ  . LYS A 1 128 ? -35.567  -19.538 -8.048  1.00 84.76  ? 335 LYS A NZ  1 
ATOM   924   N N   . GLU A 1 129 ? -42.857  -18.769 -9.022  1.00 64.64  ? 336 GLU A N   1 
ATOM   925   C CA  . GLU A 1 129 ? -43.526  -18.500 -10.318 1.00 64.90  ? 336 GLU A CA  1 
ATOM   926   C C   . GLU A 1 129 ? -45.037  -18.453 -10.127 1.00 64.65  ? 336 GLU A C   1 
ATOM   927   O O   . GLU A 1 129 ? -45.747  -18.472 -11.138 1.00 71.38  ? 336 GLU A O   1 
ATOM   928   C CB  . GLU A 1 129 ? -43.145  -19.583 -11.326 1.00 71.73  ? 336 GLU A CB  1 
ATOM   929   C CG  . GLU A 1 129 ? -41.661  -19.648 -11.638 1.00 72.86  ? 336 GLU A CG  1 
ATOM   930   C CD  . GLU A 1 129 ? -41.088  -18.419 -12.320 1.00 91.78  ? 336 GLU A CD  1 
ATOM   931   O OE1 . GLU A 1 129 ? -40.063  -17.904 -11.836 1.00 92.51  ? 336 GLU A OE1 1 
ATOM   932   O OE2 . GLU A 1 129 ? -41.662  -17.983 -13.337 1.00 104.36 ? 336 GLU A OE2 1 
ATOM   933   N N   . VAL A 1 130 ? -45.522  -18.462 -8.887  1.00 60.88  ? 337 VAL A N   1 
ATOM   934   C CA  . VAL A 1 130 ? -46.977  -18.257 -8.612  1.00 59.58  ? 337 VAL A CA  1 
ATOM   935   C C   . VAL A 1 130 ? -47.076  -17.427 -7.326  1.00 68.76  ? 337 VAL A C   1 
ATOM   936   O O   . VAL A 1 130 ? -46.115  -17.422 -6.543  1.00 67.36  ? 337 VAL A O   1 
ATOM   937   C CB  . VAL A 1 130 ? -47.812  -19.549 -8.501  1.00 59.30  ? 337 VAL A CB  1 
ATOM   938   C CG1 . VAL A 1 130 ? -48.249  -20.112 -9.842  1.00 55.35  ? 337 VAL A CG1 1 
ATOM   939   C CG2 . VAL A 1 130 ? -47.174  -20.612 -7.637  1.00 65.31  ? 337 VAL A CG2 1 
ATOM   940   N N   . ASP A 1 131 ? -48.194  -16.732 -7.127  1.00 68.27  ? 338 ASP A N   1 
ATOM   941   C CA  . ASP A 1 131 ? -48.361  -15.945 -5.901  1.00 72.07  ? 338 ASP A CA  1 
ATOM   942   C C   . ASP A 1 131 ? -48.949  -16.842 -4.813  1.00 73.58  ? 338 ASP A C   1 
ATOM   943   O O   . ASP A 1 131 ? -50.170  -16.997 -4.693  1.00 72.20  ? 338 ASP A O   1 
ATOM   944   C CB  . ASP A 1 131 ? -49.229  -14.720 -6.152  1.00 69.49  ? 338 ASP A CB  1 
ATOM   945   N N   . TYR A 1 132 ? -48.067  -17.432 -4.000  1.00 68.36  ? 339 TYR A N   1 
ATOM   946   C CA  . TYR A 1 132 ? -48.475  -18.371 -2.956  1.00 60.53  ? 339 TYR A CA  1 
ATOM   947   C C   . TYR A 1 132 ? -47.392  -18.420 -1.891  1.00 63.73  ? 339 TYR A C   1 
ATOM   948   O O   . TYR A 1 132 ? -46.221  -18.674 -2.212  1.00 58.13  ? 339 TYR A O   1 
ATOM   949   C CB  . TYR A 1 132 ? -48.710  -19.747 -3.533  1.00 56.92  ? 339 TYR A CB  1 
ATOM   950   C CG  . TYR A 1 132 ? -49.384  -20.724 -2.596  1.00 59.66  ? 339 TYR A CG  1 
ATOM   951   C CD1 . TYR A 1 132 ? -48.663  -21.416 -1.636  1.00 57.41  ? 339 TYR A CD1 1 
ATOM   952   C CD2 . TYR A 1 132 ? -50.739  -20.983 -2.697  1.00 58.80  ? 339 TYR A CD2 1 
ATOM   953   C CE1 . TYR A 1 132 ? -49.285  -22.334 -0.801  1.00 59.26  ? 339 TYR A CE1 1 
ATOM   954   C CE2 . TYR A 1 132 ? -51.366  -21.892 -1.863  1.00 59.77  ? 339 TYR A CE2 1 
ATOM   955   C CZ  . TYR A 1 132 ? -50.639  -22.569 -0.922  1.00 58.50  ? 339 TYR A CZ  1 
ATOM   956   O OH  . TYR A 1 132 ? -51.274  -23.480 -0.102  1.00 59.30  ? 339 TYR A OH  1 
ATOM   957   N N   . ARG A 1 133 ? -47.790  -18.196 -0.629  1.00 62.48  ? 340 ARG A N   1 
ATOM   958   C CA  . ARG A 1 133 ? -46.896  -18.103 0.519   1.00 54.00  ? 340 ARG A CA  1 
ATOM   959   C C   . ARG A 1 133 ? -47.481  -18.914 1.664   1.00 52.16  ? 340 ARG A C   1 
ATOM   960   O O   . ARG A 1 133 ? -48.702  -19.059 1.765   1.00 52.56  ? 340 ARG A O   1 
ATOM   961   C CB  . ARG A 1 133 ? -46.693  -16.639 0.959   1.00 51.19  ? 340 ARG A CB  1 
ATOM   962   N N   . SER A 1 134 ? -46.601  -19.444 2.524   1.00 50.19  ? 341 SER A N   1 
ATOM   963   C CA  . SER A 1 134 ? -47.027  -20.204 3.695   1.00 45.04  ? 341 SER A CA  1 
ATOM   964   C C   . SER A 1 134 ? -46.055  -19.996 4.858   1.00 49.81  ? 341 SER A C   1 
ATOM   965   O O   . SER A 1 134 ? -44.895  -19.616 4.678   1.00 53.22  ? 341 SER A O   1 
ATOM   966   C CB  . SER A 1 134 ? -47.160  -21.695 3.375   1.00 43.29  ? 341 SER A CB  1 
ATOM   967   O OG  . SER A 1 134 ? -47.947  -22.347 4.352   1.00 47.30  ? 341 SER A OG  1 
ATOM   968   N N   . ASP A 1 135 ? -46.543  -20.271 6.065   1.00 45.94  ? 342 ASP A N   1 
ATOM   969   C CA  . ASP A 1 135 ? -45.741  -20.059 7.291   1.00 44.14  ? 342 ASP A CA  1 
ATOM   970   C C   . ASP A 1 135 ? -45.890  -21.266 8.207   1.00 47.09  ? 342 ASP A C   1 
ATOM   971   O O   . ASP A 1 135 ? -46.968  -21.875 8.199   1.00 52.67  ? 342 ASP A O   1 
ATOM   972   C CB  . ASP A 1 135 ? -46.261  -18.867 8.094   1.00 50.31  ? 342 ASP A CB  1 
ATOM   973   C CG  . ASP A 1 135 ? -46.007  -17.488 7.519   1.00 54.89  ? 342 ASP A CG  1 
ATOM   974   O OD1 . ASP A 1 135 ? -45.148  -17.362 6.639   1.00 61.71  ? 342 ASP A OD1 1 
ATOM   975   O OD2 . ASP A 1 135 ? -46.673  -16.547 7.975   1.00 59.94  ? 342 ASP A OD2 1 
ATOM   976   N N   . ARG A 1 136 ? -44.861  -21.573 8.993   1.00 48.55  ? 343 ARG A N   1 
ATOM   977   C CA  . ARG A 1 136 ? -44.961  -22.667 9.990   1.00 48.26  ? 343 ARG A CA  1 
ATOM   978   C C   . ARG A 1 136 ? -44.106  -22.309 11.203  1.00 48.75  ? 343 ARG A C   1 
ATOM   979   O O   . ARG A 1 136 ? -42.921  -22.037 11.028  1.00 50.17  ? 343 ARG A O   1 
ATOM   980   C CB  . ARG A 1 136 ? -44.565  -24.005 9.368   1.00 45.98  ? 343 ARG A CB  1 
ATOM   981   C CG  . ARG A 1 136 ? -44.704  -25.209 10.287  1.00 51.54  ? 343 ARG A CG  1 
ATOM   982   C CD  . ARG A 1 136 ? -45.975  -25.270 11.103  1.00 43.28  ? 343 ARG A CD  1 
ATOM   983   N NE  . ARG A 1 136 ? -47.144  -25.533 10.287  1.00 47.87  ? 343 ARG A NE  1 
ATOM   984   C CZ  . ARG A 1 136 ? -47.654  -26.735 10.075  1.00 61.17  ? 343 ARG A CZ  1 
ATOM   985   N NH1 . ARG A 1 136 ? -47.092  -27.800 10.619  1.00 57.42  ? 343 ARG A NH1 1 
ATOM   986   N NH2 . ARG A 1 136 ? -48.725  -26.869 9.319   1.00 59.20  ? 343 ARG A NH2 1 
ATOM   987   N N   . ARG A 1 137 ? -44.709  -22.311 12.388  1.00 47.29  ? 344 ARG A N   1 
ATOM   988   C CA  . ARG A 1 137 ? -43.990  -21.976 13.637  1.00 49.09  ? 344 ARG A CA  1 
ATOM   989   C C   . ARG A 1 137 ? -43.834  -23.237 14.483  1.00 54.92  ? 344 ARG A C   1 
ATOM   990   O O   . ARG A 1 137 ? -44.860  -23.827 14.841  1.00 56.13  ? 344 ARG A O   1 
ATOM   991   C CB  . ARG A 1 137 ? -44.781  -20.921 14.403  1.00 42.66  ? 344 ARG A CB  1 
ATOM   992   C CG  . ARG A 1 137 ? -44.433  -19.491 14.046  1.00 39.33  ? 344 ARG A CG  1 
ATOM   993   C CD  . ARG A 1 137 ? -45.684  -18.652 14.036  1.00 47.75  ? 344 ARG A CD  1 
ATOM   994   N NE  . ARG A 1 137 ? -45.538  -17.561 13.091  1.00 48.40  ? 344 ARG A NE  1 
ATOM   995   C CZ  . ARG A 1 137 ? -46.029  -17.559 11.864  1.00 40.86  ? 344 ARG A CZ  1 
ATOM   996   N NH1 . ARG A 1 137 ? -45.833  -16.513 11.082  1.00 41.20  ? 344 ARG A NH1 1 
ATOM   997   N NH2 . ARG A 1 137 ? -46.722  -18.592 11.427  1.00 41.24  ? 344 ARG A NH2 1 
ATOM   998   N N   . GLU A 1 138 ? -42.599  -23.615 14.811  1.00 47.03  ? 345 GLU A N   1 
ATOM   999   C CA  . GLU A 1 138 ? -42.353  -24.848 15.543  1.00 43.86  ? 345 GLU A CA  1 
ATOM   1000  C C   . GLU A 1 138 ? -41.411  -24.607 16.717  1.00 50.71  ? 345 GLU A C   1 
ATOM   1001  O O   . GLU A 1 138 ? -40.415  -23.879 16.604  1.00 54.31  ? 345 GLU A O   1 
ATOM   1002  C CB  . GLU A 1 138 ? -41.797  -25.924 14.595  1.00 49.65  ? 345 GLU A CB  1 
ATOM   1003  C CG  . GLU A 1 138 ? -42.736  -26.199 13.418  1.00 49.87  ? 345 GLU A CG  1 
ATOM   1004  C CD  . GLU A 1 138 ? -42.068  -26.896 12.254  1.00 56.95  ? 345 GLU A CD  1 
ATOM   1005  O OE1 . GLU A 1 138 ? -41.558  -26.207 11.325  1.00 55.14  ? 345 GLU A OE1 1 
ATOM   1006  O OE2 . GLU A 1 138 ? -42.086  -28.147 12.269  1.00 54.57  ? 345 GLU A OE2 1 
ATOM   1007  N N   . ASP A 1 139 ? -41.776  -25.237 17.827  1.00 43.63  ? 346 ASP A N   1 
ATOM   1008  C CA  . ASP A 1 139 ? -40.986  -25.133 19.065  1.00 37.06  ? 346 ASP A CA  1 
ATOM   1009  C C   . ASP A 1 139 ? -39.761  -26.030 18.967  1.00 45.37  ? 346 ASP A C   1 
ATOM   1010  O O   . ASP A 1 139 ? -39.755  -26.942 18.145  1.00 44.40  ? 346 ASP A O   1 
ATOM   1011  C CB  . ASP A 1 139 ? -41.851  -25.553 20.248  1.00 43.57  ? 346 ASP A CB  1 
ATOM   1012  C CG  . ASP A 1 139 ? -42.860  -24.519 20.690  1.00 42.07  ? 346 ASP A CG  1 
ATOM   1013  O OD1 . ASP A 1 139 ? -42.483  -23.345 20.777  1.00 47.49  ? 346 ASP A OD1 1 
ATOM   1014  O OD2 . ASP A 1 139 ? -44.002  -24.906 20.967  1.00 48.71  ? 346 ASP A OD2 1 
ATOM   1015  N N   . TYR A 1 140 ? -38.756  -25.757 19.786  1.00 49.81  ? 347 TYR A N   1 
ATOM   1016  C CA  . TYR A 1 140 ? -37.536  -26.548 19.786  1.00 44.98  ? 347 TYR A CA  1 
ATOM   1017  C C   . TYR A 1 140 ? -36.896  -26.519 21.161  1.00 48.28  ? 347 TYR A C   1 
ATOM   1018  O O   . TYR A 1 140 ? -36.969  -25.522 21.887  1.00 50.34  ? 347 TYR A O   1 
ATOM   1019  C CB  . TYR A 1 140 ? -36.543  -26.037 18.744  1.00 41.27  ? 347 TYR A CB  1 
ATOM   1020  C CG  . TYR A 1 140 ? -36.041  -24.637 18.996  1.00 49.16  ? 347 TYR A CG  1 
ATOM   1021  C CD1 . TYR A 1 140 ? -34.959  -24.407 19.843  1.00 48.00  ? 347 TYR A CD1 1 
ATOM   1022  C CD2 . TYR A 1 140 ? -36.619  -23.547 18.361  1.00 44.17  ? 347 TYR A CD2 1 
ATOM   1023  C CE1 . TYR A 1 140 ? -34.488  -23.142 20.057  1.00 44.63  ? 347 TYR A CE1 1 
ATOM   1024  C CE2 . TYR A 1 140 ? -36.140  -22.278 18.560  1.00 46.19  ? 347 TYR A CE2 1 
ATOM   1025  C CZ  . TYR A 1 140 ? -35.086  -22.076 19.418  1.00 47.38  ? 347 TYR A CZ  1 
ATOM   1026  O OH  . TYR A 1 140 ? -34.624  -20.798 19.612  1.00 47.08  ? 347 TYR A OH  1 
ATOM   1027  N N   . TYR A 1 141 ? -36.237  -27.610 21.500  1.00 46.32  ? 348 TYR A N   1 
ATOM   1028  C CA  . TYR A 1 141 ? -35.482  -27.655 22.730  1.00 40.85  ? 348 TYR A CA  1 
ATOM   1029  C C   . TYR A 1 141 ? -33.985  -27.702 22.493  1.00 36.67  ? 348 TYR A C   1 
ATOM   1030  O O   . TYR A 1 141 ? -33.228  -27.803 23.457  1.00 43.37  ? 348 TYR A O   1 
ATOM   1031  C CB  . TYR A 1 141 ? -35.919  -28.853 23.563  1.00 41.86  ? 348 TYR A CB  1 
ATOM   1032  C CG  . TYR A 1 141 ? -37.325  -28.760 24.127  1.00 46.59  ? 348 TYR A CG  1 
ATOM   1033  C CD1 . TYR A 1 141 ? -38.420  -28.579 23.305  1.00 42.84  ? 348 TYR A CD1 1 
ATOM   1034  C CD2 . TYR A 1 141 ? -37.552  -28.878 25.495  1.00 49.89  ? 348 TYR A CD2 1 
ATOM   1035  C CE1 . TYR A 1 141 ? -39.690  -28.517 23.822  1.00 45.57  ? 348 TYR A CE1 1 
ATOM   1036  C CE2 . TYR A 1 141 ? -38.822  -28.816 26.018  1.00 49.92  ? 348 TYR A CE2 1 
ATOM   1037  C CZ  . TYR A 1 141 ? -39.889  -28.643 25.178  1.00 50.59  ? 348 TYR A CZ  1 
ATOM   1038  O OH  . TYR A 1 141 ? -41.160  -28.593 25.710  1.00 55.42  ? 348 TYR A OH  1 
ATOM   1039  N N   . ASP A 1 142 ? -33.583  -27.715 21.230  1.00 36.36  ? 349 ASP A N   1 
ATOM   1040  C CA  . ASP A 1 142 ? -32.156  -27.805 20.843  1.00 41.77  ? 349 ASP A CA  1 
ATOM   1041  C C   . ASP A 1 142 ? -32.023  -27.353 19.393  1.00 43.83  ? 349 ASP A C   1 
ATOM   1042  O O   . ASP A 1 142 ? -33.039  -27.305 18.687  1.00 45.93  ? 349 ASP A O   1 
ATOM   1043  C CB  . ASP A 1 142 ? -31.589  -29.217 20.991  1.00 36.51  ? 349 ASP A CB  1 
ATOM   1044  C CG  . ASP A 1 142 ? -32.313  -30.305 20.226  1.00 43.97  ? 349 ASP A CG  1 
ATOM   1045  O OD1 . ASP A 1 142 ? -33.502  -30.143 19.907  1.00 51.60  ? 349 ASP A OD1 1 
ATOM   1046  O OD2 . ASP A 1 142 ? -31.677  -31.326 19.990  1.00 39.64  ? 349 ASP A OD2 1 
ATOM   1047  N N   . ILE A 1 143 ? -30.798  -27.059 18.970  1.00 34.95  ? 350 ILE A N   1 
ATOM   1048  C CA  . ILE A 1 143 ? -30.584  -26.652 17.551  1.00 37.37  ? 350 ILE A CA  1 
ATOM   1049  C C   . ILE A 1 143 ? -29.472  -27.488 16.929  1.00 40.98  ? 350 ILE A C   1 
ATOM   1050  O O   . ILE A 1 143 ? -28.363  -27.477 17.462  1.00 46.42  ? 350 ILE A O   1 
ATOM   1051  C CB  . ILE A 1 143 ? -30.265  -25.146 17.434  1.00 36.84  ? 350 ILE A CB  1 
ATOM   1052  C CG1 . ILE A 1 143 ? -31.318  -24.264 18.106  1.00 42.61  ? 350 ILE A CG1 1 
ATOM   1053  C CG2 . ILE A 1 143 ? -30.057  -24.736 15.987  1.00 34.59  ? 350 ILE A CG2 1 
ATOM   1054  C CD1 . ILE A 1 143 ? -30.846  -22.863 18.368  1.00 41.76  ? 350 ILE A CD1 1 
ATOM   1055  N N   . GLN A 1 144 ? -29.771  -28.108 15.796  1.00 38.27  ? 351 GLN A N   1 
ATOM   1056  C CA  . GLN A 1 144 ? -28.791  -28.930 15.061  1.00 39.66  ? 351 GLN A CA  1 
ATOM   1057  C C   . GLN A 1 144 ? -28.052  -27.999 14.112  1.00 44.26  ? 351 GLN A C   1 
ATOM   1058  O O   . GLN A 1 144 ? -28.688  -27.451 13.212  1.00 44.91  ? 351 GLN A O   1 
ATOM   1059  C CB  . GLN A 1 144 ? -29.539  -30.065 14.372  1.00 33.84  ? 351 GLN A CB  1 
ATOM   1060  C CG  . GLN A 1 144 ? -30.109  -31.106 15.321  1.00 33.89  ? 351 GLN A CG  1 
ATOM   1061  C CD  . GLN A 1 144 ? -31.408  -30.729 15.988  1.00 41.96  ? 351 GLN A CD  1 
ATOM   1062  O OE1 . GLN A 1 144 ? -32.211  -29.964 15.464  1.00 46.20  ? 351 GLN A OE1 1 
ATOM   1063  N NE2 . GLN A 1 144 ? -31.618  -31.265 17.174  1.00 42.92  ? 351 GLN A NE2 1 
ATOM   1064  N N   . LEU A 1 145 ? -26.754  -27.831 14.323  1.00 44.33  ? 352 LEU A N   1 
ATOM   1065  C CA  . LEU A 1 145 ? -25.932  -26.908 13.547  1.00 43.04  ? 352 LEU A CA  1 
ATOM   1066  C C   . LEU A 1 145 ? -25.004  -27.685 12.623  1.00 50.31  ? 352 LEU A C   1 
ATOM   1067  O O   . LEU A 1 145 ? -24.285  -28.582 13.074  1.00 51.08  ? 352 LEU A O   1 
ATOM   1068  C CB  . LEU A 1 145 ? -25.103  -26.013 14.467  1.00 41.06  ? 352 LEU A CB  1 
ATOM   1069  C CG  . LEU A 1 145 ? -25.817  -24.944 15.291  1.00 45.67  ? 352 LEU A CG  1 
ATOM   1070  C CD1 . LEU A 1 145 ? -24.818  -24.139 16.121  1.00 39.47  ? 352 LEU A CD1 1 
ATOM   1071  C CD2 . LEU A 1 145 ? -26.621  -24.036 14.375  1.00 43.70  ? 352 LEU A CD2 1 
ATOM   1072  N N   . SER A 1 146 ? -25.008  -27.338 11.336  1.00 54.95  ? 353 SER A N   1 
ATOM   1073  C CA  . SER A 1 146 ? -24.110  -28.018 10.413  1.00 51.48  ? 353 SER A CA  1 
ATOM   1074  C C   . SER A 1 146 ? -22.663  -27.580 10.632  1.00 58.72  ? 353 SER A C   1 
ATOM   1075  O O   . SER A 1 146 ? -22.381  -26.475 11.115  1.00 56.19  ? 353 SER A O   1 
ATOM   1076  C CB  . SER A 1 146 ? -24.503  -27.763 8.967   1.00 53.58  ? 353 SER A CB  1 
ATOM   1077  O OG  . SER A 1 146 ? -25.897  -27.835 8.799   1.00 59.71  ? 353 SER A OG  1 
ATOM   1078  N N   . ILE A 1 147 ? -21.737  -28.468 10.241  1.00 63.68  ? 354 ILE A N   1 
ATOM   1079  C CA  . ILE A 1 147 ? -20.320  -28.351 10.577  1.00 57.44  ? 354 ILE A CA  1 
ATOM   1080  C C   . ILE A 1 147 ? -19.447  -28.408 9.337   1.00 57.51  ? 354 ILE A C   1 
ATOM   1081  O O   . ILE A 1 147 ? -18.591  -27.535 9.151   1.00 60.16  ? 354 ILE A O   1 
ATOM   1082  C CB  . ILE A 1 147 ? -19.899  -29.443 11.571  1.00 56.80  ? 354 ILE A CB  1 
ATOM   1083  C CG1 . ILE A 1 147 ? -20.644  -29.229 12.887  1.00 62.38  ? 354 ILE A CG1 1 
ATOM   1084  C CG2 . ILE A 1 147 ? -18.386  -29.430 11.789  1.00 54.79  ? 354 ILE A CG2 1 
ATOM   1085  C CD1 . ILE A 1 147 ? -20.367  -27.897 13.541  1.00 53.61  ? 354 ILE A CD1 1 
ATOM   1086  N N   . LYS A 1 148 ? -19.638  -29.434 8.497   1.00 54.68  ? 355 LYS A N   1 
ATOM   1087  C CA  . LYS A 1 148 ? -18.799  -29.607 7.309   1.00 62.04  ? 355 LYS A CA  1 
ATOM   1088  C C   . LYS A 1 148 ? -18.833  -28.348 6.449   1.00 64.27  ? 355 LYS A C   1 
ATOM   1089  O O   . LYS A 1 148 ? -19.891  -27.945 5.953   1.00 68.79  ? 355 LYS A O   1 
ATOM   1090  C CB  . LYS A 1 148 ? -19.238  -30.821 6.483   1.00 51.37  ? 355 LYS A CB  1 
ATOM   1091  N N   . GLY A 1 149 ? -17.675  -27.709 6.304   1.00 58.00  ? 356 GLY A N   1 
ATOM   1092  C CA  . GLY A 1 149 ? -17.545  -26.550 5.460   1.00 56.01  ? 356 GLY A CA  1 
ATOM   1093  C C   . GLY A 1 149 ? -17.711  -25.228 6.163   1.00 60.35  ? 356 GLY A C   1 
ATOM   1094  O O   . GLY A 1 149 ? -17.488  -24.185 5.541   1.00 68.03  ? 356 GLY A O   1 
ATOM   1095  N N   . LYS A 1 150 ? -18.072  -25.265 7.441   1.00 58.71  ? 357 LYS A N   1 
ATOM   1096  C CA  . LYS A 1 150 ? -18.251  -24.025 8.235   1.00 61.93  ? 357 LYS A CA  1 
ATOM   1097  C C   . LYS A 1 150 ? -17.076  -23.898 9.205   1.00 63.42  ? 357 LYS A C   1 
ATOM   1098  O O   . LYS A 1 150 ? -16.746  -24.896 9.861   1.00 62.37  ? 357 LYS A O   1 
ATOM   1099  C CB  . LYS A 1 150 ? -19.619  -24.050 8.920   1.00 61.44  ? 357 LYS A CB  1 
ATOM   1100  C CG  . LYS A 1 150 ? -20.763  -23.519 8.072   1.00 57.71  ? 357 LYS A CG  1 
ATOM   1101  C CD  . LYS A 1 150 ? -21.973  -24.418 8.067   1.00 62.05  ? 357 LYS A CD  1 
ATOM   1102  C CE  . LYS A 1 150 ? -21.903  -25.514 7.026   1.00 72.19  ? 357 LYS A CE  1 
ATOM   1103  N NZ  . LYS A 1 150 ? -21.558  -24.991 5.684   1.00 66.81  ? 357 LYS A NZ  1 
ATOM   1104  N N   . LYS A 1 151 ? -16.470  -22.713 9.283   1.00 61.46  ? 358 LYS A N   1 
ATOM   1105  C CA  . LYS A 1 151 ? -15.281  -22.549 10.104  1.00 57.83  ? 358 LYS A CA  1 
ATOM   1106  C C   . LYS A 1 151 ? -15.637  -22.339 11.563  1.00 63.89  ? 358 LYS A C   1 
ATOM   1107  O O   . LYS A 1 151 ? -14.853  -22.713 12.442  1.00 61.08  ? 358 LYS A O   1 
ATOM   1108  C CB  . LYS A 1 151 ? -14.433  -21.375 9.597   1.00 50.94  ? 358 LYS A CB  1 
ATOM   1109  N N   . ASN A 1 152 ? -16.804  -21.758 11.845  1.00 64.84  ? 359 ASN A N   1 
ATOM   1110  C CA  . ASN A 1 152 ? -17.143  -21.395 13.212  1.00 63.33  ? 359 ASN A CA  1 
ATOM   1111  C C   . ASN A 1 152 ? -18.653  -21.364 13.384  1.00 59.14  ? 359 ASN A C   1 
ATOM   1112  O O   . ASN A 1 152 ? -19.420  -21.544 12.437  1.00 57.21  ? 359 ASN A O   1 
ATOM   1113  C CB  . ASN A 1 152 ? -16.548  -20.040 13.595  1.00 60.57  ? 359 ASN A CB  1 
ATOM   1114  C CG  . ASN A 1 152 ? -16.982  -18.942 12.669  1.00 58.87  ? 359 ASN A CG  1 
ATOM   1115  O OD1 . ASN A 1 152 ? -18.130  -18.888 12.253  1.00 64.42  ? 359 ASN A OD1 1 
ATOM   1116  N ND2 . ASN A 1 152 ? -16.059  -18.063 12.324  1.00 60.83  ? 359 ASN A ND2 1 
ATOM   1117  N N   . ILE A 1 153 ? -19.067  -21.075 14.614  1.00 56.86  ? 360 ILE A N   1 
ATOM   1118  C CA  . ILE A 1 153 ? -20.481  -21.053 14.944  1.00 61.01  ? 360 ILE A CA  1 
ATOM   1119  C C   . ILE A 1 153 ? -21.201  -19.948 14.172  1.00 61.10  ? 360 ILE A C   1 
ATOM   1120  O O   . ILE A 1 153 ? -22.340  -20.141 13.731  1.00 55.03  ? 360 ILE A O   1 
ATOM   1121  C CB  . ILE A 1 153 ? -20.634  -20.920 16.476  1.00 61.15  ? 360 ILE A CB  1 
ATOM   1122  C CG1 . ILE A 1 153 ? -21.988  -21.431 16.932  1.00 60.70  ? 360 ILE A CG1 1 
ATOM   1123  C CG2 . ILE A 1 153 ? -20.476  -19.474 16.949  1.00 65.87  ? 360 ILE A CG2 1 
ATOM   1124  C CD1 . ILE A 1 153 ? -22.292  -21.044 18.339  1.00 60.22  ? 360 ILE A CD1 1 
ATOM   1125  N N   . PHE A 1 154 ? -20.523  -18.839 13.890  1.00 64.43  ? 361 PHE A N   1 
ATOM   1126  C CA  . PHE A 1 154 ? -21.210  -17.717 13.214  1.00 54.80  ? 361 PHE A CA  1 
ATOM   1127  C C   . PHE A 1 154 ? -21.643  -18.192 11.836  1.00 56.47  ? 361 PHE A C   1 
ATOM   1128  O O   . PHE A 1 154 ? -22.829  -18.082 11.529  1.00 59.58  ? 361 PHE A O   1 
ATOM   1129  C CB  . PHE A 1 154 ? -20.297  -16.500 13.109  1.00 65.33  ? 361 PHE A CB  1 
ATOM   1130  N N   . GLU A 1 155 ? -20.707  -18.734 11.059  1.00 53.35  ? 362 GLU A N   1 
ATOM   1131  C CA  . GLU A 1 155 ? -21.078  -19.259 9.748   1.00 56.50  ? 362 GLU A CA  1 
ATOM   1132  C C   . GLU A 1 155 ? -22.149  -20.348 9.837   1.00 56.94  ? 362 GLU A C   1 
ATOM   1133  O O   . GLU A 1 155 ? -22.865  -20.591 8.857   1.00 53.85  ? 362 GLU A O   1 
ATOM   1134  C CB  . GLU A 1 155 ? -19.829  -19.788 9.047   1.00 58.32  ? 362 GLU A CB  1 
ATOM   1135  C CG  . GLU A 1 155 ? -18.752  -18.734 8.868   1.00 65.16  ? 362 GLU A CG  1 
ATOM   1136  C CD  . GLU A 1 155 ? -17.813  -19.048 7.714   1.00 65.30  ? 362 GLU A CD  1 
ATOM   1137  O OE1 . GLU A 1 155 ? -17.080  -18.125 7.276   1.00 58.08  ? 362 GLU A OE1 1 
ATOM   1138  O OE2 . GLU A 1 155 ? -17.813  -20.219 7.260   1.00 62.50  ? 362 GLU A OE2 1 
ATOM   1139  N N   . SER A 1 156 ? -22.299  -20.988 10.993  1.00 55.59  ? 363 SER A N   1 
ATOM   1140  C CA  . SER A 1 156 ? -23.288  -22.088 11.141  1.00 54.49  ? 363 SER A CA  1 
ATOM   1141  C C   . SER A 1 156 ? -24.709  -21.529 11.254  1.00 54.05  ? 363 SER A C   1 
ATOM   1142  O O   . SER A 1 156 ? -25.604  -22.134 10.662  1.00 50.56  ? 363 SER A O   1 
ATOM   1143  C CB  . SER A 1 156 ? -22.952  -22.971 12.302  1.00 53.25  ? 363 SER A CB  1 
ATOM   1144  O OG  . SER A 1 156 ? -23.433  -24.281 12.088  1.00 54.16  ? 363 SER A OG  1 
ATOM   1145  N N   . PHE A 1 157 ? -24.911  -20.436 11.996  1.00 52.51  ? 364 PHE A N   1 
ATOM   1146  C CA  . PHE A 1 157 ? -26.237  -19.823 12.052  1.00 47.91  ? 364 PHE A CA  1 
ATOM   1147  C C   . PHE A 1 157 ? -26.584  -19.109 10.755  1.00 50.43  ? 364 PHE A C   1 
ATOM   1148  O O   . PHE A 1 157 ? -27.767  -19.021 10.394  1.00 47.75  ? 364 PHE A O   1 
ATOM   1149  C CB  . PHE A 1 157 ? -26.320  -18.837 13.209  1.00 47.64  ? 364 PHE A CB  1 
ATOM   1150  C CG  . PHE A 1 157 ? -26.635  -19.464 14.506  1.00 50.48  ? 364 PHE A CG  1 
ATOM   1151  C CD1 . PHE A 1 157 ? -25.629  -19.997 15.287  1.00 54.61  ? 364 PHE A CD1 1 
ATOM   1152  C CD2 . PHE A 1 157 ? -27.931  -19.535 14.949  1.00 48.96  ? 364 PHE A CD2 1 
ATOM   1153  C CE1 . PHE A 1 157 ? -25.907  -20.583 16.495  1.00 46.97  ? 364 PHE A CE1 1 
ATOM   1154  C CE2 . PHE A 1 157 ? -28.220  -20.116 16.152  1.00 48.35  ? 364 PHE A CE2 1 
ATOM   1155  C CZ  . PHE A 1 157 ? -27.202  -20.632 16.933  1.00 50.56  ? 364 PHE A CZ  1 
ATOM   1156  N N   . VAL A 1 158 ? -25.580  -18.561 10.065  1.00 49.73  ? 365 VAL A N   1 
ATOM   1157  C CA  . VAL A 1 158 ? -25.839  -17.968 8.763   1.00 49.22  ? 365 VAL A CA  1 
ATOM   1158  C C   . VAL A 1 158 ? -26.433  -19.007 7.838   1.00 48.83  ? 365 VAL A C   1 
ATOM   1159  O O   . VAL A 1 158 ? -27.511  -18.810 7.269   1.00 55.84  ? 365 VAL A O   1 
ATOM   1160  C CB  . VAL A 1 158 ? -24.561  -17.365 8.170   1.00 50.81  ? 365 VAL A CB  1 
ATOM   1161  C CG1 . VAL A 1 158 ? -24.869  -16.791 6.811   1.00 44.73  ? 365 VAL A CG1 1 
ATOM   1162  C CG2 . VAL A 1 158 ? -24.036  -16.293 9.091   1.00 50.86  ? 365 VAL A CG2 1 
ATOM   1163  N N   . ASP A 1 159 ? -25.753  -20.144 7.704   1.00 52.68  ? 366 ASP A N   1 
ATOM   1164  C CA  . ASP A 1 159 ? -26.269  -21.238 6.887   1.00 49.72  ? 366 ASP A CA  1 
ATOM   1165  C C   . ASP A 1 159 ? -27.660  -21.635 7.342   1.00 49.42  ? 366 ASP A C   1 
ATOM   1166  O O   . ASP A 1 159 ? -28.559  -21.823 6.514   1.00 51.80  ? 366 ASP A O   1 
ATOM   1167  C CB  . ASP A 1 159 ? -25.312  -22.430 6.957   1.00 55.18  ? 366 ASP A CB  1 
ATOM   1168  C CG  . ASP A 1 159 ? -25.630  -23.523 5.950   1.00 65.06  ? 366 ASP A CG  1 
ATOM   1169  O OD1 . ASP A 1 159 ? -25.174  -23.404 4.791   1.00 70.26  ? 366 ASP A OD1 1 
ATOM   1170  O OD2 . ASP A 1 159 ? -26.302  -24.520 6.330   1.00 69.45  ? 366 ASP A OD2 1 
ATOM   1171  N N   . TYR A 1 160 ? -27.867  -21.723 8.656   1.00 43.79  ? 367 TYR A N   1 
ATOM   1172  C CA  . TYR A 1 160 ? -29.149  -22.186 9.174   1.00 46.17  ? 367 TYR A CA  1 
ATOM   1173  C C   . TYR A 1 160 ? -30.276  -21.283 8.696   1.00 47.93  ? 367 TYR A C   1 
ATOM   1174  O O   . TYR A 1 160 ? -31.300  -21.762 8.186   1.00 51.23  ? 367 TYR A O   1 
ATOM   1175  C CB  . TYR A 1 160 ? -29.086  -22.254 10.698  1.00 39.21  ? 367 TYR A CB  1 
ATOM   1176  C CG  . TYR A 1 160 ? -30.209  -22.983 11.383  1.00 41.37  ? 367 TYR A CG  1 
ATOM   1177  C CD1 . TYR A 1 160 ? -31.405  -22.345 11.682  1.00 44.25  ? 367 TYR A CD1 1 
ATOM   1178  C CD2 . TYR A 1 160 ? -30.055  -24.298 11.793  1.00 43.97  ? 367 TYR A CD2 1 
ATOM   1179  C CE1 . TYR A 1 160 ? -32.418  -23.014 12.331  1.00 42.00  ? 367 TYR A CE1 1 
ATOM   1180  C CE2 . TYR A 1 160 ? -31.053  -24.975 12.432  1.00 32.36  ? 367 TYR A CE2 1 
ATOM   1181  C CZ  . TYR A 1 160 ? -32.232  -24.338 12.688  1.00 41.83  ? 367 TYR A CZ  1 
ATOM   1182  O OH  . TYR A 1 160 ? -33.218  -25.037 13.337  1.00 47.36  ? 367 TYR A OH  1 
ATOM   1183  N N   . VAL A 1 161 ? -30.076  -19.962 8.794   1.00 45.73  ? 368 VAL A N   1 
ATOM   1184  C CA  . VAL A 1 161 ? -31.088  -18.986 8.372   1.00 50.79  ? 368 VAL A CA  1 
ATOM   1185  C C   . VAL A 1 161 ? -31.024  -18.644 6.876   1.00 50.13  ? 368 VAL A C   1 
ATOM   1186  O O   . VAL A 1 161 ? -31.885  -17.893 6.380   1.00 45.84  ? 368 VAL A O   1 
ATOM   1187  C CB  . VAL A 1 161 ? -30.970  -17.689 9.201   1.00 44.73  ? 368 VAL A CB  1 
ATOM   1188  C CG1 . VAL A 1 161 ? -31.065  -18.013 10.644  1.00 46.78  ? 368 VAL A CG1 1 
ATOM   1189  C CG2 . VAL A 1 161 ? -29.656  -16.984 8.900   1.00 43.42  ? 368 VAL A CG2 1 
ATOM   1190  N N   . ALA A 1 162 ? -30.041  -19.174 6.147   1.00 45.46  ? 369 ALA A N   1 
ATOM   1191  C CA  . ALA A 1 162 ? -29.938  -18.951 4.717   1.00 40.01  ? 369 ALA A CA  1 
ATOM   1192  C C   . ALA A 1 162 ? -31.212  -19.402 4.013   1.00 47.49  ? 369 ALA A C   1 
ATOM   1193  O O   . ALA A 1 162 ? -32.020  -20.154 4.568   1.00 59.35  ? 369 ALA A O   1 
ATOM   1194  C CB  . ALA A 1 162 ? -28.727  -19.686 4.170   1.00 38.16  ? 369 ALA A CB  1 
ATOM   1195  N N   . VAL A 1 163 ? -31.403  -18.916 2.782   1.00 49.99  ? 370 VAL A N   1 
ATOM   1196  C CA  . VAL A 1 163 ? -32.606  -19.186 1.985   1.00 45.02  ? 370 VAL A CA  1 
ATOM   1197  C C   . VAL A 1 163 ? -32.343  -20.347 1.038   1.00 48.90  ? 370 VAL A C   1 
ATOM   1198  O O   . VAL A 1 163 ? -31.370  -20.326 0.272   1.00 50.38  ? 370 VAL A O   1 
ATOM   1199  C CB  . VAL A 1 163 ? -33.043  -17.947 1.186   1.00 46.27  ? 370 VAL A CB  1 
ATOM   1200  C CG1 . VAL A 1 163 ? -33.994  -18.355 0.084   1.00 52.64  ? 370 VAL A CG1 1 
ATOM   1201  C CG2 . VAL A 1 163 ? -33.726  -16.949 2.087   1.00 41.49  ? 370 VAL A CG2 1 
ATOM   1202  N N   . GLU A 1 164 ? -33.239  -21.334 1.049   1.00 53.64  ? 371 GLU A N   1 
ATOM   1203  C CA  . GLU A 1 164 ? -33.121  -22.546 0.244   1.00 45.61  ? 371 GLU A CA  1 
ATOM   1204  C C   . GLU A 1 164 ? -34.045  -22.526 -0.964  1.00 50.86  ? 371 GLU A C   1 
ATOM   1205  O O   . GLU A 1 164 ? -35.109  -21.901 -0.953  1.00 56.03  ? 371 GLU A O   1 
ATOM   1206  C CB  . GLU A 1 164 ? -33.474  -23.771 1.063   1.00 44.00  ? 371 GLU A CB  1 
ATOM   1207  C CG  . GLU A 1 164 ? -32.611  -24.041 2.196   1.00 47.04  ? 371 GLU A CG  1 
ATOM   1208  C CD  . GLU A 1 164 ? -32.811  -25.439 2.659   1.00 50.15  ? 371 GLU A CD  1 
ATOM   1209  O OE1 . GLU A 1 164 ? -32.274  -26.352 1.981   1.00 51.10  ? 371 GLU A OE1 1 
ATOM   1210  O OE2 . GLU A 1 164 ? -33.526  -25.615 3.673   1.00 49.91  ? 371 GLU A OE2 1 
ATOM   1211  N N   . GLN A 1 165 ? -33.660  -23.281 -1.985  1.00 48.81  ? 372 GLN A N   1 
ATOM   1212  C CA  . GLN A 1 165 ? -34.450  -23.419 -3.200  1.00 44.56  ? 372 GLN A CA  1 
ATOM   1213  C C   . GLN A 1 165 ? -35.129  -24.772 -3.151  1.00 49.79  ? 372 GLN A C   1 
ATOM   1214  O O   . GLN A 1 165 ? -34.481  -25.801 -3.365  1.00 56.98  ? 372 GLN A O   1 
ATOM   1215  C CB  . GLN A 1 165 ? -33.575  -23.304 -4.436  1.00 43.81  ? 372 GLN A CB  1 
ATOM   1216  C CG  . GLN A 1 165 ? -32.927  -21.959 -4.573  1.00 47.39  ? 372 GLN A CG  1 
ATOM   1217  C CD  . GLN A 1 165 ? -33.956  -20.854 -4.649  1.00 56.28  ? 372 GLN A CD  1 
ATOM   1218  O OE1 . GLN A 1 165 ? -35.006  -21.009 -5.297  1.00 62.51  ? 372 GLN A OE1 1 
ATOM   1219  N NE2 . GLN A 1 165 ? -33.680  -19.743 -3.990  1.00 55.36  ? 372 GLN A NE2 1 
ATOM   1220  N N   . LEU A 1 166 ? -36.429  -24.780 -2.881  1.00 49.30  ? 373 LEU A N   1 
ATOM   1221  C CA  . LEU A 1 166 ? -37.213  -26.012 -2.983  1.00 47.68  ? 373 LEU A CA  1 
ATOM   1222  C C   . LEU A 1 166 ? -37.457  -26.305 -4.467  1.00 48.76  ? 373 LEU A C   1 
ATOM   1223  O O   . LEU A 1 166 ? -38.390  -25.781 -5.072  1.00 50.12  ? 373 LEU A O   1 
ATOM   1224  C CB  . LEU A 1 166 ? -38.510  -25.886 -2.191  1.00 47.43  ? 373 LEU A CB  1 
ATOM   1225  C CG  . LEU A 1 166 ? -38.430  -25.715 -0.668  1.00 42.25  ? 373 LEU A CG  1 
ATOM   1226  C CD1 . LEU A 1 166 ? -39.827  -25.797 -0.009  1.00 39.00  ? 373 LEU A CD1 1 
ATOM   1227  C CD2 . LEU A 1 166 ? -37.499  -26.708 -0.038  1.00 30.87  ? 373 LEU A CD2 1 
ATOM   1228  N N   . ASP A 1 167 ? -36.581  -27.113 -5.050  1.00 54.94  ? 374 ASP A N   1 
ATOM   1229  C CA  . ASP A 1 167 ? -36.634  -27.316 -6.513  1.00 50.46  ? 374 ASP A CA  1 
ATOM   1230  C C   . ASP A 1 167 ? -36.545  -28.775 -6.923  1.00 53.68  ? 374 ASP A C   1 
ATOM   1231  O O   . ASP A 1 167 ? -36.063  -29.585 -6.127  1.00 48.09  ? 374 ASP A O   1 
ATOM   1232  C CB  . ASP A 1 167 ? -35.404  -26.669 -7.149  1.00 44.82  ? 374 ASP A CB  1 
ATOM   1233  C CG  . ASP A 1 167 ? -35.618  -25.287 -7.730  1.00 61.67  ? 374 ASP A CG  1 
ATOM   1234  O OD1 . ASP A 1 167 ? -36.343  -24.491 -7.110  1.00 72.45  ? 374 ASP A OD1 1 
ATOM   1235  O OD2 . ASP A 1 167 ? -35.031  -25.014 -8.790  1.00 66.02  ? 374 ASP A OD2 1 
ATOM   1236  N N   . GLY A 1 168 ? -37.022  -29.089 -8.121  1.00 52.27  ? 375 GLY A N   1 
ATOM   1237  C CA  . GLY A 1 168 ? -36.837  -30.399 -8.722  1.00 51.17  ? 375 GLY A CA  1 
ATOM   1238  C C   . GLY A 1 168 ? -37.508  -31.566 -8.024  1.00 54.43  ? 375 GLY A C   1 
ATOM   1239  O O   . GLY A 1 168 ? -38.736  -31.693 -8.099  1.00 59.79  ? 375 GLY A O   1 
ATOM   1240  N N   . ASP A 1 169 ? -36.725  -32.443 -7.366  1.00 45.12  ? 376 ASP A N   1 
ATOM   1241  C CA  . ASP A 1 169 ? -37.290  -33.537 -6.585  1.00 43.21  ? 376 ASP A CA  1 
ATOM   1242  C C   . ASP A 1 169 ? -37.774  -33.077 -5.211  1.00 46.30  ? 376 ASP A C   1 
ATOM   1243  O O   . ASP A 1 169 ? -38.143  -33.906 -4.365  1.00 40.32  ? 376 ASP A O   1 
ATOM   1244  C CB  . ASP A 1 169 ? -36.263  -34.669 -6.432  1.00 45.53  ? 376 ASP A CB  1 
ATOM   1245  C CG  . ASP A 1 169 ? -36.891  -35.978 -5.924  1.00 42.42  ? 376 ASP A CG  1 
ATOM   1246  O OD1 . ASP A 1 169 ? -38.097  -36.197 -6.120  1.00 45.18  ? 376 ASP A OD1 1 
ATOM   1247  O OD2 . ASP A 1 169 ? -36.186  -36.795 -5.323  1.00 43.06  ? 376 ASP A OD2 1 
ATOM   1248  N N   . ASN A 1 170 ? -37.757  -31.769 -4.978  1.00 45.04  ? 377 ASN A N   1 
ATOM   1249  C CA  . ASN A 1 170 ? -38.140  -31.155 -3.715  1.00 46.63  ? 377 ASN A CA  1 
ATOM   1250  C C   . ASN A 1 170 ? -38.896  -29.856 -3.978  1.00 51.93  ? 377 ASN A C   1 
ATOM   1251  O O   . ASN A 1 170 ? -38.639  -28.821 -3.350  1.00 43.56  ? 377 ASN A O   1 
ATOM   1252  C CB  . ASN A 1 170 ? -36.918  -30.891 -2.838  1.00 42.31  ? 377 ASN A CB  1 
ATOM   1253  C CG  . ASN A 1 170 ? -36.226  -32.158 -2.388  1.00 42.38  ? 377 ASN A CG  1 
ATOM   1254  O OD1 . ASN A 1 170 ? -36.752  -32.911 -1.561  1.00 46.21  ? 377 ASN A OD1 1 
ATOM   1255  N ND2 . ASN A 1 170 ? -35.023  -32.383 -2.898  1.00 38.91  ? 377 ASN A ND2 1 
ATOM   1256  N N   . LYS A 1 171 ? -39.814  -29.886 -4.939  1.00 48.08  ? 378 LYS A N   1 
ATOM   1257  C CA  . LYS A 1 171 ? -40.722  -28.774 -5.119  1.00 46.13  ? 378 LYS A CA  1 
ATOM   1258  C C   . LYS A 1 171 ? -41.763  -28.754 -4.008  1.00 50.85  ? 378 LYS A C   1 
ATOM   1259  O O   . LYS A 1 171 ? -42.044  -29.767 -3.355  1.00 51.00  ? 378 LYS A O   1 
ATOM   1260  C CB  . LYS A 1 171 ? -41.398  -28.843 -6.486  1.00 49.76  ? 378 LYS A CB  1 
ATOM   1261  C CG  . LYS A 1 171 ? -40.453  -29.238 -7.621  1.00 55.62  ? 378 LYS A CG  1 
ATOM   1262  C CD  . LYS A 1 171 ? -40.681  -28.406 -8.884  1.00 54.80  ? 378 LYS A CD  1 
ATOM   1263  C CE  . LYS A 1 171 ? -41.995  -28.748 -9.532  1.00 59.35  ? 378 LYS A CE  1 
ATOM   1264  N NZ  . LYS A 1 171 ? -41.980  -30.156 -10.046 1.00 69.85  ? 378 LYS A NZ  1 
ATOM   1265  N N   . TYR A 1 172 ? -42.334  -27.577 -3.790  1.00 49.81  ? 379 TYR A N   1 
ATOM   1266  C CA  . TYR A 1 172 ? -43.273  -27.367 -2.696  1.00 52.33  ? 379 TYR A CA  1 
ATOM   1267  C C   . TYR A 1 172 ? -44.706  -27.658 -3.154  1.00 52.44  ? 379 TYR A C   1 
ATOM   1268  O O   . TYR A 1 172 ? -45.080  -27.363 -4.294  1.00 49.52  ? 379 TYR A O   1 
ATOM   1269  C CB  . TYR A 1 172 ? -43.125  -25.930 -2.173  1.00 50.33  ? 379 TYR A CB  1 
ATOM   1270  C CG  . TYR A 1 172 ? -44.149  -25.529 -1.154  1.00 44.13  ? 379 TYR A CG  1 
ATOM   1271  C CD1 . TYR A 1 172 ? -44.273  -26.219 0.040   1.00 44.87  ? 379 TYR A CD1 1 
ATOM   1272  C CD2 . TYR A 1 172 ? -44.993  -24.465 -1.390  1.00 43.63  ? 379 TYR A CD2 1 
ATOM   1273  C CE1 . TYR A 1 172 ? -45.212  -25.855 0.970   1.00 49.29  ? 379 TYR A CE1 1 
ATOM   1274  C CE2 . TYR A 1 172 ? -45.940  -24.095 -0.470  1.00 48.35  ? 379 TYR A CE2 1 
ATOM   1275  C CZ  . TYR A 1 172 ? -46.045  -24.793 0.709   1.00 49.44  ? 379 TYR A CZ  1 
ATOM   1276  O OH  . TYR A 1 172 ? -46.982  -24.429 1.636   1.00 49.06  ? 379 TYR A OH  1 
ATOM   1277  N N   . ASP A 1 173 ? -45.502  -28.254 -2.262  1.00 49.84  ? 380 ASP A N   1 
ATOM   1278  C CA  . ASP A 1 173 ? -46.892  -28.614 -2.567  1.00 51.86  ? 380 ASP A CA  1 
ATOM   1279  C C   . ASP A 1 173 ? -47.795  -27.401 -2.349  1.00 55.69  ? 380 ASP A C   1 
ATOM   1280  O O   . ASP A 1 173 ? -48.509  -27.286 -1.347  1.00 58.61  ? 380 ASP A O   1 
ATOM   1281  C CB  . ASP A 1 173 ? -47.343  -29.793 -1.709  1.00 52.23  ? 380 ASP A CB  1 
ATOM   1282  C CG  . ASP A 1 173 ? -48.779  -30.208 -1.988  1.00 56.99  ? 380 ASP A CG  1 
ATOM   1283  O OD1 . ASP A 1 173 ? -49.405  -29.654 -2.928  1.00 57.32  ? 380 ASP A OD1 1 
ATOM   1284  O OD2 . ASP A 1 173 ? -49.270  -31.111 -1.273  1.00 57.99  ? 380 ASP A OD2 1 
ATOM   1285  N N   . ALA A 1 174 ? -47.798  -26.507 -3.340  1.00 52.14  ? 381 ALA A N   1 
ATOM   1286  C CA  . ALA A 1 174 ? -48.542  -25.255 -3.261  1.00 51.64  ? 381 ALA A CA  1 
ATOM   1287  C C   . ALA A 1 174 ? -50.027  -25.416 -3.559  1.00 56.47  ? 381 ALA A C   1 
ATOM   1288  O O   . ALA A 1 174 ? -50.580  -24.692 -4.393  1.00 61.26  ? 381 ALA A O   1 
ATOM   1289  C CB  . ALA A 1 174 ? -47.940  -24.236 -4.218  1.00 53.30  ? 381 ALA A CB  1 
ATOM   1290  N N   . GLY A 1 175 ? -50.670  -26.374 -2.900  1.00 58.82  ? 382 GLY A N   1 
ATOM   1291  C CA  . GLY A 1 175 ? -52.128  -26.432 -2.874  1.00 59.88  ? 382 GLY A CA  1 
ATOM   1292  C C   . GLY A 1 175 ? -52.782  -26.528 -4.238  1.00 57.92  ? 382 GLY A C   1 
ATOM   1293  O O   . GLY A 1 175 ? -52.513  -27.435 -5.031  1.00 55.39  ? 382 GLY A O   1 
ATOM   1294  N N   . GLU A 1 176 ? -53.614  -25.544 -4.557  1.00 68.74  ? 383 GLU A N   1 
ATOM   1295  C CA  . GLU A 1 176 ? -54.338  -25.547 -5.850  1.00 64.87  ? 383 GLU A CA  1 
ATOM   1296  C C   . GLU A 1 176 ? -53.348  -25.395 -6.995  1.00 62.91  ? 383 GLU A C   1 
ATOM   1297  O O   . GLU A 1 176 ? -53.695  -25.791 -8.118  1.00 62.10  ? 383 GLU A O   1 
ATOM   1298  C CB  . GLU A 1 176 ? -55.316  -24.377 -5.880  1.00 60.94  ? 383 GLU A CB  1 
ATOM   1299  N N   . HIS A 1 177 ? -52.169  -24.850 -6.715  1.00 54.65  ? 384 HIS A N   1 
ATOM   1300  C CA  . HIS A 1 177 ? -51.187  -24.581 -7.792  1.00 57.76  ? 384 HIS A CA  1 
ATOM   1301  C C   . HIS A 1 177 ? -50.310  -25.810 -8.028  1.00 54.97  ? 384 HIS A C   1 
ATOM   1302  O O   . HIS A 1 177 ? -49.497  -25.774 -8.957  1.00 52.08  ? 384 HIS A O   1 
ATOM   1303  C CB  . HIS A 1 177 ? -50.367  -23.341 -7.443  1.00 60.42  ? 384 HIS A CB  1 
ATOM   1304  C CG  . HIS A 1 177 ? -51.169  -22.131 -7.112  1.00 68.91  ? 384 HIS A CG  1 
ATOM   1305  N ND1 . HIS A 1 177 ? -51.599  -21.247 -8.076  1.00 70.98  ? 384 HIS A ND1 1 
ATOM   1306  C CD2 . HIS A 1 177 ? -51.591  -21.636 -5.931  1.00 66.73  ? 384 HIS A CD2 1 
ATOM   1307  C CE1 . HIS A 1 177 ? -52.262  -20.264 -7.504  1.00 65.61  ? 384 HIS A CE1 1 
ATOM   1308  N NE2 . HIS A 1 177 ? -52.271  -20.480 -6.188  1.00 64.53  ? 384 HIS A NE2 1 
ATOM   1309  N N   . GLY A 1 178 ? -50.471  -26.847 -7.213  1.00 52.28  ? 385 GLY A N   1 
ATOM   1310  C CA  . GLY A 1 178 ? -49.708  -28.093 -7.384  1.00 47.77  ? 385 GLY A CA  1 
ATOM   1311  C C   . GLY A 1 178 ? -48.280  -27.965 -6.911  1.00 55.91  ? 385 GLY A C   1 
ATOM   1312  O O   . GLY A 1 178 ? -47.987  -27.047 -6.148  1.00 59.08  ? 385 GLY A O   1 
ATOM   1313  N N   . LEU A 1 179 ? -47.416  -28.864 -7.367  1.00 51.72  ? 386 LEU A N   1 
ATOM   1314  C CA  . LEU A 1 179 ? -45.988  -28.791 -6.993  1.00 45.94  ? 386 LEU A CA  1 
ATOM   1315  C C   . LEU A 1 179 ? -45.369  -27.599 -7.712  1.00 51.84  ? 386 LEU A C   1 
ATOM   1316  O O   . LEU A 1 179 ? -45.494  -27.525 -8.940  1.00 60.80  ? 386 LEU A O   1 
ATOM   1317  C CB  . LEU A 1 179 ? -45.301  -30.102 -7.370  1.00 53.67  ? 386 LEU A CB  1 
ATOM   1318  C CG  . LEU A 1 179 ? -45.620  -31.292 -6.471  1.00 49.34  ? 386 LEU A CG  1 
ATOM   1319  C CD1 . LEU A 1 179 ? -45.021  -32.565 -7.041  1.00 50.11  ? 386 LEU A CD1 1 
ATOM   1320  C CD2 . LEU A 1 179 ? -45.109  -31.053 -5.063  1.00 49.29  ? 386 LEU A CD2 1 
ATOM   1321  N N   . GLN A 1 180 ? -44.735  -26.700 -6.966  1.00 54.30  ? 387 GLN A N   1 
ATOM   1322  C CA  . GLN A 1 180 ? -44.158  -25.477 -7.567  1.00 49.48  ? 387 GLN A CA  1 
ATOM   1323  C C   . GLN A 1 180 ? -42.799  -25.174 -6.952  1.00 49.99  ? 387 GLN A C   1 
ATOM   1324  O O   . GLN A 1 180 ? -42.649  -25.399 -5.752  1.00 53.99  ? 387 GLN A O   1 
ATOM   1325  C CB  . GLN A 1 180 ? -45.065  -24.282 -7.283  1.00 51.97  ? 387 GLN A CB  1 
ATOM   1326  C CG  . GLN A 1 180 ? -46.432  -24.334 -7.944  1.00 52.20  ? 387 GLN A CG  1 
ATOM   1327  C CD  . GLN A 1 180 ? -46.414  -23.763 -9.338  1.00 49.83  ? 387 GLN A CD  1 
ATOM   1328  O OE1 . GLN A 1 180 ? -45.566  -22.946 -9.688  1.00 42.85  ? 387 GLN A OE1 1 
ATOM   1329  N NE2 . GLN A 1 180 ? -47.362  -24.194 -10.149 1.00 50.47  ? 387 GLN A NE2 1 
ATOM   1330  N N   . GLU A 1 181 ? -41.843  -24.685 -7.745  1.00 42.95  ? 388 GLU A N   1 
ATOM   1331  C CA  . GLU A 1 181 ? -40.587  -24.240 -7.185  1.00 41.24  ? 388 GLU A CA  1 
ATOM   1332  C C   . GLU A 1 181 ? -40.874  -23.171 -6.132  1.00 51.77  ? 388 GLU A C   1 
ATOM   1333  O O   . GLU A 1 181 ? -41.857  -22.431 -6.223  1.00 53.03  ? 388 GLU A O   1 
ATOM   1334  C CB  . GLU A 1 181 ? -39.682  -23.728 -8.302  1.00 44.00  ? 388 GLU A CB  1 
ATOM   1335  C CG  . GLU A 1 181 ? -39.389  -24.835 -9.315  1.00 49.10  ? 388 GLU A CG  1 
ATOM   1336  C CD  . GLU A 1 181 ? -38.529  -24.398 -10.488 1.00 58.72  ? 388 GLU A CD  1 
ATOM   1337  O OE1 . GLU A 1 181 ? -38.041  -23.245 -10.494 1.00 67.64  ? 388 GLU A OE1 1 
ATOM   1338  O OE2 . GLU A 1 181 ? -38.344  -25.216 -11.415 1.00 58.39  ? 388 GLU A OE2 1 
ATOM   1339  N N   . ALA A 1 182 ? -40.041  -23.120 -5.095  1.00 48.39  ? 389 ALA A N   1 
ATOM   1340  C CA  . ALA A 1 182 ? -40.263  -22.142 -4.048  1.00 45.45  ? 389 ALA A CA  1 
ATOM   1341  C C   . ALA A 1 182 ? -38.976  -21.931 -3.269  1.00 52.42  ? 389 ALA A C   1 
ATOM   1342  O O   . ALA A 1 182 ? -38.048  -22.735 -3.342  1.00 50.33  ? 389 ALA A O   1 
ATOM   1343  C CB  . ALA A 1 182 ? -41.387  -22.577 -3.110  1.00 46.29  ? 389 ALA A CB  1 
ATOM   1344  N N   . GLU A 1 183 ? -38.944  -20.827 -2.518  1.00 52.66  ? 390 GLU A N   1 
ATOM   1345  C CA  . GLU A 1 183 ? -37.883  -20.523 -1.577  1.00 43.20  ? 390 GLU A CA  1 
ATOM   1346  C C   . GLU A 1 183 ? -38.360  -20.803 -0.163  1.00 51.70  ? 390 GLU A C   1 
ATOM   1347  O O   . GLU A 1 183 ? -39.525  -20.560 0.168   1.00 55.75  ? 390 GLU A O   1 
ATOM   1348  C CB  . GLU A 1 183 ? -37.453  -19.066 -1.690  1.00 49.04  ? 390 GLU A CB  1 
ATOM   1349  C CG  . GLU A 1 183 ? -36.769  -18.713 -2.996  1.00 59.74  ? 390 GLU A CG  1 
ATOM   1350  C CD  . GLU A 1 183 ? -36.259  -17.277 -3.034  1.00 65.12  ? 390 GLU A CD  1 
ATOM   1351  O OE1 . GLU A 1 183 ? -36.857  -16.407 -2.355  1.00 71.16  ? 390 GLU A OE1 1 
ATOM   1352  O OE2 . GLU A 1 183 ? -35.261  -17.022 -3.749  1.00 61.66  ? 390 GLU A OE2 1 
ATOM   1353  N N   . LYS A 1 184 ? -37.452  -21.306 0.676   1.00 53.71  ? 391 LYS A N   1 
ATOM   1354  C CA  . LYS A 1 184 ? -37.742  -21.640 2.068   1.00 47.42  ? 391 LYS A CA  1 
ATOM   1355  C C   . LYS A 1 184 ? -36.691  -21.001 2.957   1.00 48.11  ? 391 LYS A C   1 
ATOM   1356  O O   . LYS A 1 184 ? -35.492  -21.060 2.666   1.00 50.69  ? 391 LYS A O   1 
ATOM   1357  C CB  . LYS A 1 184 ? -37.767  -23.151 2.315   1.00 45.97  ? 391 LYS A CB  1 
ATOM   1358  C CG  . LYS A 1 184 ? -38.198  -23.557 3.727   1.00 51.33  ? 391 LYS A CG  1 
ATOM   1359  C CD  . LYS A 1 184 ? -38.028  -25.060 3.956   1.00 47.98  ? 391 LYS A CD  1 
ATOM   1360  C CE  . LYS A 1 184 ? -38.602  -25.536 5.275   1.00 45.37  ? 391 LYS A CE  1 
ATOM   1361  N NZ  . LYS A 1 184 ? -37.542  -25.720 6.317   1.00 46.75  ? 391 LYS A NZ  1 
ATOM   1362  N N   . GLY A 1 185 ? -37.149  -20.379 4.033   1.00 51.10  ? 392 GLY A N   1 
ATOM   1363  C CA  . GLY A 1 185 ? -36.254  -19.683 4.923   1.00 45.43  ? 392 GLY A CA  1 
ATOM   1364  C C   . GLY A 1 185 ? -36.692  -19.811 6.357   1.00 45.32  ? 392 GLY A C   1 
ATOM   1365  O O   . GLY A 1 185 ? -37.887  -19.794 6.650   1.00 47.19  ? 392 GLY A O   1 
ATOM   1366  N N   . VAL A 1 186 ? -35.726  -19.952 7.252   1.00 49.00  ? 393 VAL A N   1 
ATOM   1367  C CA  . VAL A 1 186 ? -35.978  -20.114 8.677   1.00 50.39  ? 393 VAL A CA  1 
ATOM   1368  C C   . VAL A 1 186 ? -35.409  -18.917 9.441   1.00 49.23  ? 393 VAL A C   1 
ATOM   1369  O O   . VAL A 1 186 ? -34.403  -18.312 9.048   1.00 51.95  ? 393 VAL A O   1 
ATOM   1370  C CB  . VAL A 1 186 ? -35.401  -21.444 9.198   1.00 41.96  ? 393 VAL A CB  1 
ATOM   1371  C CG1 . VAL A 1 186 ? -35.561  -21.526 10.704  1.00 45.46  ? 393 VAL A CG1 1 
ATOM   1372  C CG2 . VAL A 1 186 ? -36.147  -22.572 8.554   1.00 40.58  ? 393 VAL A CG2 1 
ATOM   1373  N N   . LYS A 1 187 ? -36.113  -18.541 10.508  1.00 44.17  ? 394 LYS A N   1 
ATOM   1374  C CA  . LYS A 1 187 ? -35.686  -17.494 11.414  1.00 42.69  ? 394 LYS A CA  1 
ATOM   1375  C C   . LYS A 1 187 ? -36.084  -17.911 12.818  1.00 51.74  ? 394 LYS A C   1 
ATOM   1376  O O   . LYS A 1 187 ? -37.008  -18.712 13.012  1.00 50.30  ? 394 LYS A O   1 
ATOM   1377  C CB  . LYS A 1 187 ? -36.311  -16.140 11.075  1.00 45.71  ? 394 LYS A CB  1 
ATOM   1378  C CG  . LYS A 1 187 ? -35.569  -15.345 10.033  1.00 52.64  ? 394 LYS A CG  1 
ATOM   1379  C CD  . LYS A 1 187 ? -34.152  -15.007 10.475  1.00 51.03  ? 394 LYS A CD  1 
ATOM   1380  C CE  . LYS A 1 187 ? -33.632  -13.716 9.804   1.00 66.56  ? 394 LYS A CE  1 
ATOM   1381  N NZ  . LYS A 1 187 ? -33.693  -13.709 8.304   1.00 61.92  ? 394 LYS A NZ  1 
ATOM   1382  N N   . PHE A 1 188 ? -35.379  -17.358 13.804  1.00 51.60  ? 395 PHE A N   1 
ATOM   1383  C CA  . PHE A 1 188 ? -35.702  -17.617 15.199  1.00 48.72  ? 395 PHE A CA  1 
ATOM   1384  C C   . PHE A 1 188 ? -36.650  -16.553 15.718  1.00 48.17  ? 395 PHE A C   1 
ATOM   1385  O O   . PHE A 1 188 ? -36.351  -15.357 15.638  1.00 48.23  ? 395 PHE A O   1 
ATOM   1386  C CB  . PHE A 1 188 ? -34.444  -17.649 16.047  1.00 48.95  ? 395 PHE A CB  1 
ATOM   1387  C CG  . PHE A 1 188 ? -33.594  -18.819 15.773  1.00 45.70  ? 395 PHE A CG  1 
ATOM   1388  C CD1 . PHE A 1 188 ? -33.835  -20.018 16.415  1.00 43.01  ? 395 PHE A CD1 1 
ATOM   1389  C CD2 . PHE A 1 188 ? -32.566  -18.735 14.858  1.00 45.12  ? 395 PHE A CD2 1 
ATOM   1390  C CE1 . PHE A 1 188 ? -33.061  -21.109 16.151  1.00 44.20  ? 395 PHE A CE1 1 
ATOM   1391  C CE2 . PHE A 1 188 ? -31.783  -19.830 14.591  1.00 45.14  ? 395 PHE A CE2 1 
ATOM   1392  C CZ  . PHE A 1 188 ? -32.031  -21.023 15.232  1.00 42.11  ? 395 PHE A CZ  1 
ATOM   1393  N N   . LEU A 1 189 ? -37.782  -16.981 16.249  1.00 40.84  ? 396 LEU A N   1 
ATOM   1394  C CA  . LEU A 1 189 ? -38.709  -16.011 16.857  1.00 41.89  ? 396 LEU A CA  1 
ATOM   1395  C C   . LEU A 1 189 ? -38.207  -15.733 18.263  1.00 44.70  ? 396 LEU A C   1 
ATOM   1396  O O   . LEU A 1 189 ? -38.101  -14.551 18.609  1.00 43.90  ? 396 LEU A O   1 
ATOM   1397  C CB  . LEU A 1 189 ? -40.103  -16.632 16.872  1.00 45.53  ? 396 LEU A CB  1 
ATOM   1398  C CG  . LEU A 1 189 ? -40.879  -16.538 15.568  1.00 42.42  ? 396 LEU A CG  1 
ATOM   1399  C CD1 . LEU A 1 189 ? -42.283  -17.073 15.763  1.00 34.94  ? 396 LEU A CD1 1 
ATOM   1400  C CD2 . LEU A 1 189 ? -40.915  -15.102 15.084  1.00 36.67  ? 396 LEU A CD2 1 
ATOM   1401  N N   . THR A 1 190 ? -37.923  -16.783 19.036  1.00 45.35  ? 397 THR A N   1 
ATOM   1402  C CA  . THR A 1 190 ? -37.374  -16.629 20.374  1.00 45.12  ? 397 THR A CA  1 
ATOM   1403  C C   . THR A 1 190 ? -36.249  -17.641 20.564  1.00 45.66  ? 397 THR A C   1 
ATOM   1404  O O   . THR A 1 190 ? -36.291  -18.739 20.007  1.00 47.42  ? 397 THR A O   1 
ATOM   1405  C CB  . THR A 1 190 ? -38.459  -16.803 21.465  1.00 35.76  ? 397 THR A CB  1 
ATOM   1406  O OG1 . THR A 1 190 ? -38.871  -18.170 21.564  1.00 40.23  ? 397 THR A OG1 1 
ATOM   1407  C CG2 . THR A 1 190 ? -39.673  -15.958 21.160  1.00 33.36  ? 397 THR A CG2 1 
ATOM   1408  N N   . LEU A 1 191 ? -35.218  -17.252 21.369  1.00 44.60  ? 398 LEU A N   1 
ATOM   1409  C CA  . LEU A 1 191 ? -34.168  -18.161 21.816  1.00 43.98  ? 398 LEU A CA  1 
ATOM   1410  C C   . LEU A 1 191 ? -34.246  -18.378 23.324  1.00 45.89  ? 398 LEU A C   1 
ATOM   1411  O O   . LEU A 1 191 ? -34.430  -17.412 24.071  1.00 45.41  ? 398 LEU A O   1 
ATOM   1412  C CB  . LEU A 1 191 ? -32.786  -17.618 21.464  1.00 48.06  ? 398 LEU A CB  1 
ATOM   1413  C CG  . LEU A 1 191 ? -32.530  -17.374 19.978  1.00 47.97  ? 398 LEU A CG  1 
ATOM   1414  C CD1 . LEU A 1 191 ? -31.768  -16.077 19.771  1.00 45.29  ? 398 LEU A CD1 1 
ATOM   1415  C CD2 . LEU A 1 191 ? -31.768  -18.539 19.360  1.00 45.94  ? 398 LEU A CD2 1 
ATOM   1416  N N   . PRO A 1 192 ? -34.079  -19.617 23.798  1.00 44.54  ? 399 PRO A N   1 
ATOM   1417  C CA  . PRO A 1 192 ? -34.391  -19.940 25.199  1.00 39.72  ? 399 PRO A CA  1 
ATOM   1418  C C   . PRO A 1 192 ? -33.306  -19.442 26.138  1.00 44.19  ? 399 PRO A C   1 
ATOM   1419  O O   . PRO A 1 192 ? -32.186  -19.135 25.706  1.00 45.65  ? 399 PRO A O   1 
ATOM   1420  C CB  . PRO A 1 192 ? -34.461  -21.472 25.195  1.00 41.85  ? 399 PRO A CB  1 
ATOM   1421  C CG  . PRO A 1 192 ? -33.516  -21.868 24.120  1.00 40.50  ? 399 PRO A CG  1 
ATOM   1422  C CD  . PRO A 1 192 ? -33.536  -20.782 23.072  1.00 40.00  ? 399 PRO A CD  1 
ATOM   1423  N N   . PRO A 1 193 ? -33.607  -19.337 27.438  1.00 46.68  ? 400 PRO A N   1 
ATOM   1424  C CA  . PRO A 1 193 ? -32.575  -18.911 28.392  1.00 41.68  ? 400 PRO A CA  1 
ATOM   1425  C C   . PRO A 1 193 ? -31.347  -19.794 28.372  1.00 45.42  ? 400 PRO A C   1 
ATOM   1426  O O   . PRO A 1 193 ? -30.215  -19.300 28.430  1.00 46.51  ? 400 PRO A O   1 
ATOM   1427  C CB  . PRO A 1 193 ? -33.315  -18.986 29.730  1.00 40.16  ? 400 PRO A CB  1 
ATOM   1428  C CG  . PRO A 1 193 ? -34.726  -18.742 29.369  1.00 47.83  ? 400 PRO A CG  1 
ATOM   1429  C CD  . PRO A 1 193 ? -34.911  -19.517 28.102  1.00 48.42  ? 400 PRO A CD  1 
ATOM   1430  N N   . VAL A 1 194 ? -31.532  -21.094 28.272  1.00 46.57  ? 401 VAL A N   1 
ATOM   1431  C CA  . VAL A 1 194 ? -30.417  -22.013 28.158  1.00 45.52  ? 401 VAL A CA  1 
ATOM   1432  C C   . VAL A 1 194 ? -30.425  -22.556 26.739  1.00 45.63  ? 401 VAL A C   1 
ATOM   1433  O O   . VAL A 1 194 ? -31.314  -23.325 26.362  1.00 48.83  ? 401 VAL A O   1 
ATOM   1434  C CB  . VAL A 1 194 ? -30.511  -23.135 29.194  1.00 46.23  ? 401 VAL A CB  1 
ATOM   1435  C CG1 . VAL A 1 194 ? -29.299  -24.033 29.090  1.00 46.84  ? 401 VAL A CG1 1 
ATOM   1436  C CG2 . VAL A 1 194 ? -30.620  -22.540 30.566  1.00 46.30  ? 401 VAL A CG2 1 
ATOM   1437  N N   . LEU A 1 195 ? -29.439  -22.171 25.945  1.00 47.45  ? 402 LEU A N   1 
ATOM   1438  C CA  . LEU A 1 195 ? -29.352  -22.657 24.552  1.00 45.21  ? 402 LEU A CA  1 
ATOM   1439  C C   . LEU A 1 195 ? -28.566  -23.966 24.509  1.00 44.87  ? 402 LEU A C   1 
ATOM   1440  O O   . LEU A 1 195 ? -27.476  -24.011 25.062  1.00 48.07  ? 402 LEU A O   1 
ATOM   1441  C CB  . LEU A 1 195 ? -28.685  -21.563 23.720  1.00 47.22  ? 402 LEU A CB  1 
ATOM   1442  C CG  . LEU A 1 195 ? -28.852  -21.659 22.211  1.00 54.04  ? 402 LEU A CG  1 
ATOM   1443  C CD1 . LEU A 1 195 ? -30.280  -21.362 21.816  1.00 49.25  ? 402 LEU A CD1 1 
ATOM   1444  C CD2 . LEU A 1 195 ? -27.912  -20.686 21.531  1.00 51.09  ? 402 LEU A CD2 1 
ATOM   1445  N N   . HIS A 1 196 ? -29.142  -25.001 23.895  1.00 30.00  ? 403 HIS A N   1 
ATOM   1446  C CA  . HIS A 1 196 ? -28.464  -26.310 23.730  1.00 30.00  ? 403 HIS A CA  1 
ATOM   1447  C C   . HIS A 1 196 ? -28.134  -26.489 22.250  1.00 30.00  ? 403 HIS A C   1 
ATOM   1448  O O   . HIS A 1 196 ? -29.067  -26.565 21.454  1.00 30.00  ? 403 HIS A O   1 
ATOM   1449  C CB  . HIS A 1 196 ? -29.348  -27.439 24.254  1.00 30.00  ? 403 HIS A CB  1 
ATOM   1450  C CG  . HIS A 1 196 ? -29.200  -27.728 25.706  1.00 30.00  ? 403 HIS A CG  1 
ATOM   1451  N ND1 . HIS A 1 196 ? -29.545  -28.944 26.246  1.00 30.00  ? 403 HIS A ND1 1 
ATOM   1452  C CD2 . HIS A 1 196 ? -28.762  -26.970 26.729  1.00 30.00  ? 403 HIS A CD2 1 
ATOM   1453  C CE1 . HIS A 1 196 ? -29.317  -28.929 27.539  1.00 30.00  ? 403 HIS A CE1 1 
ATOM   1454  N NE2 . HIS A 1 196 ? -28.836  -27.731 27.859  1.00 30.00  ? 403 HIS A NE2 1 
ATOM   1455  N N   . LEU A 1 197 ? -26.850  -26.533 21.903  1.00 43.74  ? 404 LEU A N   1 
ATOM   1456  C CA  . LEU A 1 197 ? -26.432  -26.609 20.485  1.00 46.97  ? 404 LEU A CA  1 
ATOM   1457  C C   . LEU A 1 197 ? -25.823  -27.979 20.191  1.00 49.80  ? 404 LEU A C   1 
ATOM   1458  O O   . LEU A 1 197 ? -24.841  -28.330 20.826  1.00 51.95  ? 404 LEU A O   1 
ATOM   1459  C CB  . LEU A 1 197 ? -25.455  -25.465 20.205  1.00 41.49  ? 404 LEU A CB  1 
ATOM   1460  C CG  . LEU A 1 197 ? -26.035  -24.065 20.375  1.00 46.22  ? 404 LEU A CG  1 
ATOM   1461  C CD1 . LEU A 1 197 ? -24.959  -23.012 20.206  1.00 41.85  ? 404 LEU A CD1 1 
ATOM   1462  C CD2 . LEU A 1 197 ? -27.161  -23.827 19.387  1.00 41.79  ? 404 LEU A CD2 1 
ATOM   1463  N N   . GLN A 1 198 ? -26.437  -28.716 19.267  1.00 42.48  ? 405 GLN A N   1 
ATOM   1464  C CA  . GLN A 1 198 ? -25.913  -30.035 18.847  1.00 46.54  ? 405 GLN A CA  1 
ATOM   1465  C C   . GLN A 1 198 ? -25.155  -29.852 17.542  1.00 45.67  ? 405 GLN A C   1 
ATOM   1466  O O   . GLN A 1 198 ? -25.777  -29.556 16.525  1.00 48.37  ? 405 GLN A O   1 
ATOM   1467  C CB  . GLN A 1 198 ? -27.031  -31.051 18.652  1.00 43.19  ? 405 GLN A CB  1 
ATOM   1468  C CG  . GLN A 1 198 ? -26.526  -32.473 18.511  1.00 40.20  ? 405 GLN A CG  1 
ATOM   1469  C CD  . GLN A 1 198 ? -27.484  -33.308 17.704  1.00 44.21  ? 405 GLN A CD  1 
ATOM   1470  O OE1 . GLN A 1 198 ? -28.656  -32.982 17.566  1.00 51.50  ? 405 GLN A OE1 1 
ATOM   1471  N NE2 . GLN A 1 198 ? -26.987  -34.405 17.170  1.00 41.15  ? 405 GLN A NE2 1 
ATOM   1472  N N   . LEU A 1 199 ? -23.844  -30.019 17.604  1.00 41.87  ? 406 LEU A N   1 
ATOM   1473  C CA  . LEU A 1 199 ? -22.994  -29.860 16.409  1.00 42.56  ? 406 LEU A CA  1 
ATOM   1474  C C   . LEU A 1 199 ? -23.094  -31.150 15.620  1.00 44.76  ? 406 LEU A C   1 
ATOM   1475  O O   . LEU A 1 199 ? -22.944  -32.208 16.211  1.00 46.35  ? 406 LEU A O   1 
ATOM   1476  C CB  . LEU A 1 199 ? -21.569  -29.552 16.870  1.00 45.81  ? 406 LEU A CB  1 
ATOM   1477  C CG  . LEU A 1 199 ? -21.430  -28.437 17.905  1.00 45.13  ? 406 LEU A CG  1 
ATOM   1478  C CD1 . LEU A 1 199 ? -19.968  -28.180 18.217  1.00 44.16  ? 406 LEU A CD1 1 
ATOM   1479  C CD2 . LEU A 1 199 ? -22.105  -27.158 17.438  1.00 38.26  ? 406 LEU A CD2 1 
ATOM   1480  N N   . MET A 1 200 ? -23.340  -31.048 14.327  1.00 47.53  ? 407 MET A N   1 
ATOM   1481  C CA  . MET A 1 200 ? -23.599  -32.233 13.524  1.00 50.59  ? 407 MET A CA  1 
ATOM   1482  C C   . MET A 1 200 ? -22.276  -32.842 13.066  1.00 52.26  ? 407 MET A C   1 
ATOM   1483  O O   . MET A 1 200 ? -21.917  -32.851 11.887  1.00 58.05  ? 407 MET A O   1 
ATOM   1484  C CB  . MET A 1 200 ? -24.504  -31.860 12.372  1.00 52.59  ? 407 MET A CB  1 
ATOM   1485  C CG  . MET A 1 200 ? -25.735  -31.196 12.878  1.00 49.64  ? 407 MET A CG  1 
ATOM   1486  S SD  . MET A 1 200 ? -27.052  -32.380 12.866  1.00 53.57  ? 407 MET A SD  1 
ATOM   1487  C CE  . MET A 1 200 ? -27.690  -32.043 11.208  1.00 40.50  ? 407 MET A CE  1 
ATOM   1488  N N   . ARG A 1 201 ? -21.545  -33.381 14.035  1.00 46.83  ? 408 ARG A N   1 
ATOM   1489  C CA  . ARG A 1 201 ? -20.219  -33.930 13.767  1.00 51.85  ? 408 ARG A CA  1 
ATOM   1490  C C   . ARG A 1 201 ? -20.328  -35.338 13.188  1.00 58.70  ? 408 ARG A C   1 
ATOM   1491  O O   . ARG A 1 201 ? -19.755  -36.298 13.706  1.00 58.28  ? 408 ARG A O   1 
ATOM   1492  C CB  . ARG A 1 201 ? -19.369  -33.930 15.031  1.00 46.71  ? 408 ARG A CB  1 
ATOM   1493  C CG  . ARG A 1 201 ? -18.713  -32.606 15.277  1.00 49.58  ? 408 ARG A CG  1 
ATOM   1494  C CD  . ARG A 1 201 ? -17.578  -32.713 16.291  1.00 56.46  ? 408 ARG A CD  1 
ATOM   1495  N NE  . ARG A 1 201 ? -16.993  -31.401 16.556  1.00 54.80  ? 408 ARG A NE  1 
ATOM   1496  C CZ  . ARG A 1 201 ? -16.095  -30.834 15.757  1.00 55.06  ? 408 ARG A CZ  1 
ATOM   1497  N NH1 . ARG A 1 201 ? -15.697  -31.495 14.676  1.00 53.51  ? 408 ARG A NH1 1 
ATOM   1498  N NH2 . ARG A 1 201 ? -15.597  -29.630 16.034  1.00 49.72  ? 408 ARG A NH2 1 
ATOM   1499  N N   . PHE A 1 202 ? -21.104  -35.446 12.109  1.00 55.50  ? 409 PHE A N   1 
ATOM   1500  C CA  . PHE A 1 202 ? -21.292  -36.761 11.453  1.00 59.76  ? 409 PHE A CA  1 
ATOM   1501  C C   . PHE A 1 202 ? -21.729  -36.640 9.992   1.00 64.30  ? 409 PHE A C   1 
ATOM   1502  O O   . PHE A 1 202 ? -22.607  -35.821 9.692   1.00 61.14  ? 409 PHE A O   1 
ATOM   1503  C CB  . PHE A 1 202 ? -22.284  -37.655 12.210  1.00 56.01  ? 409 PHE A CB  1 
ATOM   1504  C CG  . PHE A 1 202 ? -23.427  -36.999 12.940  1.00 53.85  ? 409 PHE A CG  1 
ATOM   1505  C CD1 . PHE A 1 202 ? -24.430  -36.332 12.258  1.00 57.67  ? 409 PHE A CD1 1 
ATOM   1506  C CD2 . PHE A 1 202 ? -23.527  -37.103 14.316  1.00 51.62  ? 409 PHE A CD2 1 
ATOM   1507  C CE1 . PHE A 1 202 ? -25.484  -35.748 12.937  1.00 55.79  ? 409 PHE A CE1 1 
ATOM   1508  C CE2 . PHE A 1 202 ? -24.581  -36.518 14.994  1.00 50.40  ? 409 PHE A CE2 1 
ATOM   1509  C CZ  . PHE A 1 202 ? -25.556  -35.842 14.304  1.00 53.79  ? 409 PHE A CZ  1 
ATOM   1510  N N   . MET A 1 203 ? -21.074  -37.376 9.100   1.00 65.14  ? 410 MET A N   1 
ATOM   1511  C CA  . MET A 1 203 ? -21.498  -37.521 7.716   1.00 66.91  ? 410 MET A CA  1 
ATOM   1512  C C   . MET A 1 203 ? -21.613  -39.007 7.425   1.00 73.71  ? 410 MET A C   1 
ATOM   1513  O O   . MET A 1 203 ? -21.043  -39.843 8.136   1.00 78.73  ? 410 MET A O   1 
ATOM   1514  C CB  . MET A 1 203 ? -20.516  -36.866 6.724   1.00 70.80  ? 410 MET A CB  1 
ATOM   1515  N N   . TYR A 1 204 ? -22.357  -39.339 6.378   1.00 76.35  ? 411 TYR A N   1 
ATOM   1516  C CA  . TYR A 1 204 ? -22.615  -40.743 6.084   1.00 74.39  ? 411 TYR A CA  1 
ATOM   1517  C C   . TYR A 1 204 ? -22.287  -41.083 4.624   1.00 75.65  ? 411 TYR A C   1 
ATOM   1518  O O   . TYR A 1 204 ? -22.245  -40.211 3.759   1.00 68.47  ? 411 TYR A O   1 
ATOM   1519  C CB  . TYR A 1 204 ? -24.071  -41.105 6.418   1.00 70.59  ? 411 TYR A CB  1 
ATOM   1520  C CG  . TYR A 1 204 ? -24.414  -42.519 6.033   1.00 75.88  ? 411 TYR A CG  1 
ATOM   1521  C CD1 . TYR A 1 204 ? -24.081  -43.573 6.863   1.00 80.66  ? 411 TYR A CD1 1 
ATOM   1522  C CD2 . TYR A 1 204 ? -25.025  -42.805 4.806   1.00 76.39  ? 411 TYR A CD2 1 
ATOM   1523  C CE1 . TYR A 1 204 ? -24.361  -44.889 6.498   1.00 87.57  ? 411 TYR A CE1 1 
ATOM   1524  C CE2 . TYR A 1 204 ? -25.311  -44.106 4.426   1.00 72.19  ? 411 TYR A CE2 1 
ATOM   1525  C CZ  . TYR A 1 204 ? -24.977  -45.151 5.277   1.00 84.47  ? 411 TYR A CZ  1 
ATOM   1526  O OH  . TYR A 1 204 ? -25.261  -46.461 4.923   1.00 78.82  ? 411 TYR A OH  1 
ATOM   1527  N N   . ASN A 1 211 ? -21.420  -44.079 9.901   1.00 79.89  ? 418 ASN A N   1 
ATOM   1528  C CA  . ASN A 1 211 ? -21.013  -42.873 10.668  1.00 82.87  ? 418 ASN A CA  1 
ATOM   1529  C C   . ASN A 1 211 ? -19.537  -42.609 10.401  1.00 72.84  ? 418 ASN A C   1 
ATOM   1530  O O   . ASN A 1 211 ? -18.707  -43.436 10.807  1.00 78.01  ? 418 ASN A O   1 
ATOM   1531  C CB  . ASN A 1 211 ? -21.288  -43.025 12.166  1.00 76.04  ? 418 ASN A CB  1 
ATOM   1532  C CG  . ASN A 1 211 ? -21.081  -41.754 12.959  1.00 77.27  ? 418 ASN A CG  1 
ATOM   1533  O OD1 . ASN A 1 211 ? -21.928  -40.868 12.945  1.00 70.72  ? 418 ASN A OD1 1 
ATOM   1534  N ND2 . ASN A 1 211 ? -19.970  -41.669 13.670  1.00 74.38  ? 418 ASN A ND2 1 
ATOM   1535  N N   . ILE A 1 212 ? -19.233  -41.495 9.745   1.00 67.66  ? 419 ILE A N   1 
ATOM   1536  C CA  . ILE A 1 212 ? -17.808  -41.145 9.503   1.00 75.00  ? 419 ILE A CA  1 
ATOM   1537  C C   . ILE A 1 212 ? -17.309  -40.309 10.682  1.00 76.79  ? 419 ILE A C   1 
ATOM   1538  O O   . ILE A 1 212 ? -16.157  -40.564 11.087  1.00 87.98  ? 419 ILE A O   1 
ATOM   1539  C CB  . ILE A 1 212 ? -17.637  -40.450 8.137   1.00 71.02  ? 419 ILE A CB  1 
ATOM   1540  C CG1 . ILE A 1 212 ? -17.698  -41.467 6.995   1.00 75.12  ? 419 ILE A CG1 1 
ATOM   1541  C CG2 . ILE A 1 212 ? -16.369  -39.612 8.064   1.00 60.31  ? 419 ILE A CG2 1 
ATOM   1542  C CD1 . ILE A 1 212 ? -16.775  -42.647 7.180   1.00 73.92  ? 419 ILE A CD1 1 
ATOM   1543  N N   . LYS A 1 213 ? -18.137  -39.411 11.227  1.00 61.45  ? 420 LYS A N   1 
ATOM   1544  C CA  . LYS A 1 213 ? -17.741  -38.491 12.336  1.00 67.39  ? 420 LYS A CA  1 
ATOM   1545  C C   . LYS A 1 213 ? -16.843  -37.376 11.802  1.00 61.81  ? 420 LYS A C   1 
ATOM   1546  O O   . LYS A 1 213 ? -15.677  -37.641 11.487  1.00 57.86  ? 420 LYS A O   1 
ATOM   1547  C CB  . LYS A 1 213 ? -17.098  -39.164 13.553  1.00 60.73  ? 420 LYS A CB  1 
ATOM   1548  C CG  . LYS A 1 213 ? -17.233  -38.357 14.834  1.00 59.19  ? 420 LYS A CG  1 
ATOM   1549  C CD  . LYS A 1 213 ? -15.996  -38.273 15.678  1.00 59.80  ? 420 LYS A CD  1 
ATOM   1550  C CE  . LYS A 1 213 ? -16.101  -37.194 16.731  1.00 51.14  ? 420 LYS A CE  1 
ATOM   1551  N NZ  . LYS A 1 213 ? -14.992  -37.280 17.708  1.00 61.31  ? 420 LYS A NZ  1 
ATOM   1552  N N   . ILE A 1 214 ? -17.385  -36.168 11.745  1.00 59.78  ? 421 ILE A N   1 
ATOM   1553  C CA  . ILE A 1 214 ? -16.627  -35.008 11.218  1.00 56.81  ? 421 ILE A CA  1 
ATOM   1554  C C   . ILE A 1 214 ? -15.743  -34.499 12.346  1.00 56.92  ? 421 ILE A C   1 
ATOM   1555  O O   . ILE A 1 214 ? -16.271  -34.056 13.366  1.00 58.13  ? 421 ILE A O   1 
ATOM   1556  C CB  . ILE A 1 214 ? -17.606  -33.951 10.680  1.00 57.99  ? 421 ILE A CB  1 
ATOM   1557  C CG1 . ILE A 1 214 ? -18.373  -34.471 9.464   1.00 57.98  ? 421 ILE A CG1 1 
ATOM   1558  C CG2 . ILE A 1 214 ? -16.903  -32.643 10.370  1.00 60.69  ? 421 ILE A CG2 1 
ATOM   1559  C CD1 . ILE A 1 214 ? -19.509  -33.579 9.044   1.00 61.07  ? 421 ILE A CD1 1 
ATOM   1560  N N   . ASN A 1 215 ? -14.435  -34.628 12.171  1.00 55.59  ? 422 ASN A N   1 
ATOM   1561  C CA  . ASN A 1 215 ? -13.511  -34.169 13.194  1.00 59.51  ? 422 ASN A CA  1 
ATOM   1562  C C   . ASN A 1 215 ? -12.878  -32.836 12.837  1.00 58.10  ? 422 ASN A C   1 
ATOM   1563  O O   . ASN A 1 215 ? -11.829  -32.492 13.381  1.00 56.13  ? 422 ASN A O   1 
ATOM   1564  C CB  . ASN A 1 215 ? -12.443  -35.228 13.456  1.00 53.43  ? 422 ASN A CB  1 
ATOM   1565  C CG  . ASN A 1 215 ? -12.943  -36.344 14.351  1.00 54.23  ? 422 ASN A CG  1 
ATOM   1566  O OD1 . ASN A 1 215 ? -13.198  -36.123 15.530  1.00 56.39  ? 422 ASN A OD1 1 
ATOM   1567  N ND2 . ASN A 1 215 ? -13.089  -37.549 13.793  1.00 48.98  ? 422 ASN A ND2 1 
ATOM   1568  N N   . ASP A 1 216 ? -13.512  -32.067 11.960  1.00 57.52  ? 423 ASP A N   1 
ATOM   1569  C CA  . ASP A 1 216 ? -12.858  -30.886 11.436  1.00 53.54  ? 423 ASP A CA  1 
ATOM   1570  C C   . ASP A 1 216 ? -12.786  -29.793 12.494  1.00 56.38  ? 423 ASP A C   1 
ATOM   1571  O O   . ASP A 1 216 ? -13.453  -29.840 13.531  1.00 60.78  ? 423 ASP A O   1 
ATOM   1572  C CB  . ASP A 1 216 ? -13.585  -30.384 10.196  1.00 58.23  ? 423 ASP A CB  1 
ATOM   1573  C CG  . ASP A 1 216 ? -13.781  -31.470 9.162   1.00 61.69  ? 423 ASP A CG  1 
ATOM   1574  O OD1 . ASP A 1 216 ? -13.445  -32.636 9.460   1.00 62.81  ? 423 ASP A OD1 1 
ATOM   1575  O OD2 . ASP A 1 216 ? -14.276  -31.159 8.052   1.00 70.60  ? 423 ASP A OD2 1 
ATOM   1576  N N   . ARG A 1 217 ? -12.017  -28.762 12.154  1.00 57.68  ? 424 ARG A N   1 
ATOM   1577  C CA  . ARG A 1 217 ? -11.906  -27.600 13.054  1.00 50.54  ? 424 ARG A CA  1 
ATOM   1578  C C   . ARG A 1 217 ? -13.204  -26.826 12.988  1.00 53.40  ? 424 ARG A C   1 
ATOM   1579  O O   . ARG A 1 217 ? -13.610  -26.425 11.888  1.00 54.81  ? 424 ARG A O   1 
ATOM   1580  C CB  . ARG A 1 217 ? -10.751  -26.679 12.662  1.00 44.22  ? 424 ARG A CB  1 
ATOM   1581  C CG  . ARG A 1 217 ? -10.511  -25.552 13.655  1.00 50.72  ? 424 ARG A CG  1 
ATOM   1582  C CD  . ARG A 1 217 ? -9.264   -24.749 13.351  1.00 49.03  ? 424 ARG A CD  1 
ATOM   1583  N NE  . ARG A 1 217 ? -8.532   -24.414 14.562  1.00 51.21  ? 424 ARG A NE  1 
ATOM   1584  C CZ  . ARG A 1 217 ? -8.559   -23.231 15.162  1.00 52.82  ? 424 ARG A CZ  1 
ATOM   1585  N NH1 . ARG A 1 217 ? -9.291   -22.249 14.667  1.00 53.56  ? 424 ARG A NH1 1 
ATOM   1586  N NH2 . ARG A 1 217 ? -7.855   -23.033 16.260  1.00 50.51  ? 424 ARG A NH2 1 
ATOM   1587  N N   . PHE A 1 218 ? -13.839  -26.676 14.131  1.00 53.15  ? 425 PHE A N   1 
ATOM   1588  C CA  . PHE A 1 218 ? -15.048  -25.868 14.235  1.00 48.69  ? 425 PHE A CA  1 
ATOM   1589  C C   . PHE A 1 218 ? -14.956  -25.049 15.512  1.00 50.88  ? 425 PHE A C   1 
ATOM   1590  O O   . PHE A 1 218 ? -14.901  -25.608 16.612  1.00 51.80  ? 425 PHE A O   1 
ATOM   1591  C CB  . PHE A 1 218 ? -16.300  -26.742 14.235  1.00 50.56  ? 425 PHE A CB  1 
ATOM   1592  C CG  . PHE A 1 218 ? -17.569  -25.967 14.325  1.00 54.58  ? 425 PHE A CG  1 
ATOM   1593  C CD1 . PHE A 1 218 ? -18.095  -25.352 13.200  1.00 57.57  ? 425 PHE A CD1 1 
ATOM   1594  C CD2 . PHE A 1 218 ? -18.238  -25.834 15.541  1.00 56.07  ? 425 PHE A CD2 1 
ATOM   1595  C CE1 . PHE A 1 218 ? -19.287  -24.620 13.279  1.00 63.82  ? 425 PHE A CE1 1 
ATOM   1596  C CE2 . PHE A 1 218 ? -19.427  -25.104 15.633  1.00 61.63  ? 425 PHE A CE2 1 
ATOM   1597  C CZ  . PHE A 1 218 ? -19.959  -24.496 14.498  1.00 60.06  ? 425 PHE A CZ  1 
ATOM   1598  N N   . GLU A 1 219 ? -14.959  -23.731 15.370  1.00 53.07  ? 426 GLU A N   1 
ATOM   1599  C CA  . GLU A 1 219 ? -14.665  -22.828 16.474  1.00 60.21  ? 426 GLU A CA  1 
ATOM   1600  C C   . GLU A 1 219 ? -15.951  -22.205 17.003  1.00 64.09  ? 426 GLU A C   1 
ATOM   1601  O O   . GLU A 1 219 ? -16.773  -21.711 16.228  1.00 66.52  ? 426 GLU A O   1 
ATOM   1602  C CB  . GLU A 1 219 ? -13.675  -21.740 16.036  1.00 55.03  ? 426 GLU A CB  1 
ATOM   1603  N N   . PHE A 1 220 ? -16.129  -22.255 18.319  1.00 57.93  ? 427 PHE A N   1 
ATOM   1604  C CA  . PHE A 1 220 ? -17.212  -21.620 19.038  1.00 52.80  ? 427 PHE A CA  1 
ATOM   1605  C C   . PHE A 1 220 ? -16.628  -20.615 20.022  1.00 58.37  ? 427 PHE A C   1 
ATOM   1606  O O   . PHE A 1 220 ? -15.487  -20.769 20.466  1.00 54.11  ? 427 PHE A O   1 
ATOM   1607  C CB  . PHE A 1 220 ? -18.056  -22.649 19.795  1.00 46.65  ? 427 PHE A CB  1 
ATOM   1608  C CG  . PHE A 1 220 ? -17.243  -23.637 20.559  1.00 53.26  ? 427 PHE A CG  1 
ATOM   1609  C CD1 . PHE A 1 220 ? -16.774  -24.799 19.949  1.00 56.68  ? 427 PHE A CD1 1 
ATOM   1610  C CD2 . PHE A 1 220 ? -16.924  -23.409 21.888  1.00 52.53  ? 427 PHE A CD2 1 
ATOM   1611  C CE1 . PHE A 1 220 ? -16.001  -25.727 20.658  1.00 50.04  ? 427 PHE A CE1 1 
ATOM   1612  C CE2 . PHE A 1 220 ? -16.159  -24.325 22.599  1.00 48.04  ? 427 PHE A CE2 1 
ATOM   1613  C CZ  . PHE A 1 220 ? -15.694  -25.491 21.974  1.00 46.87  ? 427 PHE A CZ  1 
ATOM   1614  N N   . PRO A 1 221 ? -17.372  -19.582 20.370  1.00 53.80  ? 428 PRO A N   1 
ATOM   1615  C CA  . PRO A 1 221 ? -16.808  -18.510 21.189  1.00 55.92  ? 428 PRO A CA  1 
ATOM   1616  C C   . PRO A 1 221 ? -17.315  -18.520 22.620  1.00 61.32  ? 428 PRO A C   1 
ATOM   1617  O O   . PRO A 1 221 ? -18.302  -19.200 22.912  1.00 63.24  ? 428 PRO A O   1 
ATOM   1618  C CB  . PRO A 1 221 ? -17.275  -17.258 20.446  1.00 65.84  ? 428 PRO A CB  1 
ATOM   1619  C CG  . PRO A 1 221 ? -18.635  -17.671 19.919  1.00 65.53  ? 428 PRO A CG  1 
ATOM   1620  C CD  . PRO A 1 221 ? -18.617  -19.166 19.713  1.00 59.10  ? 428 PRO A CD  1 
ATOM   1621  N N   . GLU A 1 222 ? -16.653  -17.759 23.513  1.00 66.63  ? 429 GLU A N   1 
ATOM   1622  C CA  . GLU A 1 222 ? -17.105  -17.582 24.897  1.00 63.40  ? 429 GLU A CA  1 
ATOM   1623  C C   . GLU A 1 222 ? -18.279  -16.614 25.012  1.00 61.00  ? 429 GLU A C   1 
ATOM   1624  O O   . GLU A 1 222 ? -19.019  -16.661 26.001  1.00 63.45  ? 429 GLU A O   1 
ATOM   1625  C CB  . GLU A 1 222 ? -15.944  -17.097 25.780  1.00 60.22  ? 429 GLU A CB  1 
ATOM   1626  N N   . GLN A 1 223 ? -18.462  -15.735 24.035  1.00 62.17  ? 430 GLN A N   1 
ATOM   1627  C CA  . GLN A 1 223 ? -19.670  -14.934 23.922  1.00 63.71  ? 430 GLN A CA  1 
ATOM   1628  C C   . GLN A 1 223 ? -20.239  -15.089 22.512  1.00 65.53  ? 430 GLN A C   1 
ATOM   1629  O O   . GLN A 1 223 ? -19.498  -15.286 21.540  1.00 57.87  ? 430 GLN A O   1 
ATOM   1630  C CB  . GLN A 1 223 ? -19.398  -13.465 24.236  1.00 66.21  ? 430 GLN A CB  1 
ATOM   1631  C CG  . GLN A 1 223 ? -18.516  -13.269 25.441  1.00 73.76  ? 430 GLN A CG  1 
ATOM   1632  C CD  . GLN A 1 223 ? -18.767  -11.952 26.153  1.00 82.14  ? 430 GLN A CD  1 
ATOM   1633  O OE1 . GLN A 1 223 ? -17.817  -11.246 26.508  1.00 88.55  ? 430 GLN A OE1 1 
ATOM   1634  N NE2 . GLN A 1 223 ? -20.044  -11.614 26.371  1.00 68.59  ? 430 GLN A NE2 1 
ATOM   1635  N N   . LEU A 1 224 ? -21.569  -15.063 22.423  1.00 61.99  ? 431 LEU A N   1 
ATOM   1636  C CA  . LEU A 1 224 ? -22.235  -15.336 21.131  1.00 55.11  ? 431 LEU A CA  1 
ATOM   1637  C C   . LEU A 1 224 ? -23.399  -14.380 20.943  1.00 56.27  ? 431 LEU A C   1 
ATOM   1638  O O   . LEU A 1 224 ? -24.422  -14.551 21.612  1.00 62.45  ? 431 LEU A O   1 
ATOM   1639  C CB  . LEU A 1 224 ? -22.718  -16.783 21.188  1.00 51.99  ? 431 LEU A CB  1 
ATOM   1640  C CG  . LEU A 1 224 ? -23.548  -17.298 20.023  1.00 51.07  ? 431 LEU A CG  1 
ATOM   1641  C CD1 . LEU A 1 224 ? -22.754  -17.274 18.735  1.00 52.02  ? 431 LEU A CD1 1 
ATOM   1642  C CD2 . LEU A 1 224 ? -24.045  -18.697 20.329  1.00 49.31  ? 431 LEU A CD2 1 
ATOM   1643  N N   . PRO A 1 225 ? -23.250  -13.343 20.107  1.00 60.13  ? 432 PRO A N   1 
ATOM   1644  C CA  . PRO A 1 225 ? -24.371  -12.473 19.787  1.00 57.25  ? 432 PRO A CA  1 
ATOM   1645  C C   . PRO A 1 225 ? -25.254  -13.082 18.691  1.00 53.91  ? 432 PRO A C   1 
ATOM   1646  O O   . PRO A 1 225 ? -24.818  -13.185 17.567  1.00 58.60  ? 432 PRO A O   1 
ATOM   1647  C CB  . PRO A 1 225 ? -23.675  -11.205 19.301  1.00 60.81  ? 432 PRO A CB  1 
ATOM   1648  C CG  . PRO A 1 225 ? -22.308  -11.631 18.817  1.00 66.37  ? 432 PRO A CG  1 
ATOM   1649  C CD  . PRO A 1 225 ? -21.980  -12.915 19.541  1.00 61.85  ? 432 PRO A CD  1 
ATOM   1650  N N   . LEU A 1 226 ? -26.479  -13.460 19.044  1.00 52.97  ? 433 LEU A N   1 
ATOM   1651  C CA  . LEU A 1 226 ? -27.378  -14.134 18.073  1.00 51.05  ? 433 LEU A CA  1 
ATOM   1652  C C   . LEU A 1 226 ? -28.535  -13.224 17.659  1.00 50.79  ? 433 LEU A C   1 
ATOM   1653  O O   . LEU A 1 226 ? -29.518  -13.749 17.132  1.00 53.76  ? 433 LEU A O   1 
ATOM   1654  C CB  . LEU A 1 226 ? -27.923  -15.394 18.740  1.00 46.54  ? 433 LEU A CB  1 
ATOM   1655  C CG  . LEU A 1 226 ? -26.934  -16.530 18.930  1.00 45.81  ? 433 LEU A CG  1 
ATOM   1656  C CD1 . LEU A 1 226 ? -27.630  -17.702 19.579  1.00 42.43  ? 433 LEU A CD1 1 
ATOM   1657  C CD2 . LEU A 1 226 ? -26.340  -16.943 17.601  1.00 46.45  ? 433 LEU A CD2 1 
ATOM   1658  N N   . ASP A 1 227 ? -28.414  -11.916 17.869  1.00 52.52  ? 434 ASP A N   1 
ATOM   1659  C CA  . ASP A 1 227 ? -29.476  -10.998 17.456  1.00 51.67  ? 434 ASP A CA  1 
ATOM   1660  C C   . ASP A 1 227 ? -29.702  -11.044 15.957  1.00 49.49  ? 434 ASP A C   1 
ATOM   1661  O O   . ASP A 1 227 ? -30.840  -10.886 15.503  1.00 52.33  ? 434 ASP A O   1 
ATOM   1662  C CB  . ASP A 1 227 ? -29.143  -9.565  17.870  1.00 53.96  ? 434 ASP A CB  1 
ATOM   1663  C CG  . ASP A 1 227 ? -29.951  -9.085  19.051  1.00 57.41  ? 434 ASP A CG  1 
ATOM   1664  O OD1 . ASP A 1 227 ? -30.719  -9.878  19.642  1.00 56.58  ? 434 ASP A OD1 1 
ATOM   1665  O OD2 . ASP A 1 227 ? -29.822  -7.887  19.373  1.00 64.88  ? 434 ASP A OD2 1 
ATOM   1666  N N   . GLU A 1 228 ? -28.633  -11.272 15.180  1.00 50.52  ? 435 GLU A N   1 
ATOM   1667  C CA  . GLU A 1 228 ? -28.739  -11.347 13.725  1.00 47.89  ? 435 GLU A CA  1 
ATOM   1668  C C   . GLU A 1 228 ? -29.668  -12.454 13.263  1.00 51.52  ? 435 GLU A C   1 
ATOM   1669  O O   . GLU A 1 228 ? -30.109  -12.423 12.111  1.00 62.59  ? 435 GLU A O   1 
ATOM   1670  C CB  . GLU A 1 228 ? -27.364  -11.548 13.077  1.00 46.39  ? 435 GLU A CB  1 
ATOM   1671  N N   . PHE A 1 229 ? -29.995  -13.422 14.116  1.00 48.61  ? 436 PHE A N   1 
ATOM   1672  C CA  . PHE A 1 229 ? -30.763  -14.573 13.665  1.00 49.79  ? 436 PHE A CA  1 
ATOM   1673  C C   . PHE A 1 229 ? -32.168  -14.583 14.220  1.00 54.10  ? 436 PHE A C   1 
ATOM   1674  O O   . PHE A 1 229 ? -32.905  -15.551 13.999  1.00 54.07  ? 436 PHE A O   1 
ATOM   1675  C CB  . PHE A 1 229 ? -30.012  -15.859 13.998  1.00 46.00  ? 436 PHE A CB  1 
ATOM   1676  C CG  . PHE A 1 229 ? -28.558  -15.782 13.628  1.00 50.45  ? 436 PHE A CG  1 
ATOM   1677  C CD1 . PHE A 1 229 ? -28.171  -15.762 12.300  1.00 48.37  ? 436 PHE A CD1 1 
ATOM   1678  C CD2 . PHE A 1 229 ? -27.590  -15.629 14.598  1.00 53.65  ? 436 PHE A CD2 1 
ATOM   1679  C CE1 . PHE A 1 229 ? -26.837  -15.656 11.953  1.00 52.79  ? 436 PHE A CE1 1 
ATOM   1680  C CE2 . PHE A 1 229 ? -26.259  -15.517 14.259  1.00 51.29  ? 436 PHE A CE2 1 
ATOM   1681  C CZ  . PHE A 1 229 ? -25.877  -15.533 12.939  1.00 49.69  ? 436 PHE A CZ  1 
ATOM   1682  N N   . LEU A 1 230 ? -32.572  -13.516 14.901  1.00 54.46  ? 437 LEU A N   1 
ATOM   1683  C CA  . LEU A 1 230 ? -33.954  -13.386 15.321  1.00 49.01  ? 437 LEU A CA  1 
ATOM   1684  C C   . LEU A 1 230 ? -34.768  -12.792 14.195  1.00 52.01  ? 437 LEU A C   1 
ATOM   1685  O O   . LEU A 1 230 ? -34.241  -12.349 13.176  1.00 56.96  ? 437 LEU A O   1 
ATOM   1686  C CB  . LEU A 1 230 ? -34.072  -12.519 16.560  1.00 55.66  ? 437 LEU A CB  1 
ATOM   1687  C CG  . LEU A 1 230 ? -33.727  -13.159 17.895  1.00 51.15  ? 437 LEU A CG  1 
ATOM   1688  C CD1 . LEU A 1 230 ? -33.730  -12.081 18.956  1.00 52.35  ? 437 LEU A CD1 1 
ATOM   1689  C CD2 . LEU A 1 230 ? -34.696  -14.247 18.228  1.00 42.88  ? 437 LEU A CD2 1 
ATOM   1690  N N   . GLN A 1 231 ? -36.079  -12.816 14.371  1.00 55.24  ? 438 GLN A N   1 
ATOM   1691  C CA  . GLN A 1 231 ? -36.949  -12.162 13.412  1.00 53.57  ? 438 GLN A CA  1 
ATOM   1692  C C   . GLN A 1 231 ? -37.168  -10.719 13.834  1.00 59.36  ? 438 GLN A C   1 
ATOM   1693  O O   . GLN A 1 231 ? -36.957  -9.801  13.037  1.00 60.82  ? 438 GLN A O   1 
ATOM   1694  C CB  . GLN A 1 231 ? -38.267  -12.935 13.296  1.00 47.92  ? 438 GLN A CB  1 
ATOM   1695  C CG  . GLN A 1 231 ? -39.446  -12.138 12.785  1.00 52.09  ? 438 GLN A CG  1 
ATOM   1696  C CD  . GLN A 1 231 ? -39.507  -12.110 11.285  1.00 48.99  ? 438 GLN A CD  1 
ATOM   1697  O OE1 . GLN A 1 231 ? -38.941  -12.961 10.628  1.00 55.35  ? 438 GLN A OE1 1 
ATOM   1698  N NE2 . GLN A 1 231 ? -40.165  -11.109 10.734  1.00 51.90  ? 438 GLN A NE2 1 
ATOM   1699  N N   . LYS A 1 232 ? -37.552  -10.516 15.098  1.00 66.82  ? 439 LYS A N   1 
ATOM   1700  C CA  . LYS A 1 232 ? -37.660  -9.198  15.729  1.00 70.08  ? 439 LYS A CA  1 
ATOM   1701  C C   . LYS A 1 232 ? -36.742  -9.172  16.948  1.00 71.64  ? 439 LYS A C   1 
ATOM   1702  O O   . LYS A 1 232 ? -37.001  -9.863  17.944  1.00 63.95  ? 439 LYS A O   1 
ATOM   1703  C CB  . LYS A 1 232 ? -39.102  -8.889  16.136  1.00 57.07  ? 439 LYS A CB  1 
ATOM   1704  N N   . THR A 1 233 ? -35.671  -8.382  16.872  1.00 71.08  ? 440 THR A N   1 
ATOM   1705  C CA  . THR A 1 233 ? -34.820  -8.189  18.038  1.00 65.90  ? 440 THR A CA  1 
ATOM   1706  C C   . THR A 1 233 ? -35.536  -7.325  19.067  1.00 74.08  ? 440 THR A C   1 
ATOM   1707  O O   . THR A 1 233 ? -36.354  -6.469  18.718  1.00 75.35  ? 440 THR A O   1 
ATOM   1708  C CB  . THR A 1 233 ? -33.502  -7.521  17.653  1.00 57.80  ? 440 THR A CB  1 
ATOM   1709  O OG1 . THR A 1 233 ? -33.723  -6.132  17.412  1.00 57.93  ? 440 THR A OG1 1 
ATOM   1710  C CG2 . THR A 1 233 ? -32.927  -8.143  16.417  1.00 55.28  ? 440 THR A CG2 1 
ATOM   1711  N N   . ASP A 1 234 ? -35.228  -7.574  20.346  1.00 81.04  ? 441 ASP A N   1 
ATOM   1712  C CA  . ASP A 1 234 ? -35.813  -6.793  21.469  1.00 85.89  ? 441 ASP A CA  1 
ATOM   1713  C C   . ASP A 1 234 ? -34.687  -6.078  22.215  1.00 87.25  ? 441 ASP A C   1 
ATOM   1714  O O   . ASP A 1 234 ? -33.785  -6.763  22.717  1.00 89.94  ? 441 ASP A O   1 
ATOM   1715  C CB  . ASP A 1 234 ? -36.560  -7.699  22.447  1.00 84.47  ? 441 ASP A CB  1 
ATOM   1716  C CG  . ASP A 1 234 ? -36.980  -7.033  23.745  1.00 86.10  ? 441 ASP A CG  1 
ATOM   1717  O OD1 . ASP A 1 234 ? -37.508  -5.909  23.687  1.00 87.02  ? 441 ASP A OD1 1 
ATOM   1718  O OD2 . ASP A 1 234 ? -36.788  -7.655  24.801  1.00 83.03  ? 441 ASP A OD2 1 
ATOM   1719  N N   . PRO A 1 235 ? -34.694  -4.734  22.300  1.00 96.66  ? 442 PRO A N   1 
ATOM   1720  C CA  . PRO A 1 235 ? -33.674  -3.995  23.049  1.00 101.86 ? 442 PRO A CA  1 
ATOM   1721  C C   . PRO A 1 235 ? -33.867  -4.005  24.574  1.00 93.31  ? 442 PRO A C   1 
ATOM   1722  O O   . PRO A 1 235 ? -33.032  -3.442  25.252  1.00 85.81  ? 442 PRO A O   1 
ATOM   1723  C CB  . PRO A 1 235 ? -33.819  -2.561  22.522  1.00 91.17  ? 442 PRO A CB  1 
ATOM   1724  C CG  . PRO A 1 235 ? -34.686  -2.689  21.289  1.00 91.71  ? 442 PRO A CG  1 
ATOM   1725  C CD  . PRO A 1 235 ? -35.612  -3.841  21.604  1.00 94.41  ? 442 PRO A CD  1 
ATOM   1726  N N   . LYS A 1 236 ? -34.938  -4.631  25.069  1.00 88.16  ? 443 LYS A N   1 
ATOM   1727  C CA  . LYS A 1 236 ? -35.147  -4.756  26.535  1.00 89.22  ? 443 LYS A CA  1 
ATOM   1728  C C   . LYS A 1 236 ? -34.538  -6.073  27.015  1.00 89.27  ? 443 LYS A C   1 
ATOM   1729  O O   . LYS A 1 236 ? -34.595  -6.320  28.231  1.00 87.30  ? 443 LYS A O   1 
ATOM   1730  C CB  . LYS A 1 236 ? -36.639  -4.671  26.863  1.00 80.84  ? 443 LYS A CB  1 
ATOM   1731  N N   . ASP A 1 237 ? -33.972  -6.865  26.103  1.00 83.12  ? 444 ASP A N   1 
ATOM   1732  C CA  . ASP A 1 237 ? -33.326  -8.134  26.429  1.00 74.33  ? 444 ASP A CA  1 
ATOM   1733  C C   . ASP A 1 237 ? -32.518  -8.588  25.219  1.00 74.79  ? 444 ASP A C   1 
ATOM   1734  O O   . ASP A 1 237 ? -32.894  -9.575  24.573  1.00 75.39  ? 444 ASP A O   1 
ATOM   1735  C CB  . ASP A 1 237 ? -34.370  -9.195  26.821  1.00 68.98  ? 444 ASP A CB  1 
ATOM   1736  C CG  . ASP A 1 237 ? -33.753  -10.548 27.248  1.00 70.00  ? 444 ASP A CG  1 
ATOM   1737  O OD1 . ASP A 1 237 ? -32.606  -10.868 26.857  1.00 71.39  ? 444 ASP A OD1 1 
ATOM   1738  O OD2 . ASP A 1 237 ? -34.435  -11.315 27.973  1.00 70.56  ? 444 ASP A OD2 1 
ATOM   1739  N N   . PRO A 1 238 ? -31.418  -7.897  24.858  1.00 74.48  ? 445 PRO A N   1 
ATOM   1740  C CA  . PRO A 1 238 ? -30.576  -8.380  23.749  1.00 69.90  ? 445 PRO A CA  1 
ATOM   1741  C C   . PRO A 1 238 ? -30.226  -9.859  23.874  1.00 68.45  ? 445 PRO A C   1 
ATOM   1742  O O   . PRO A 1 238 ? -30.370  -10.452 24.955  1.00 64.71  ? 445 PRO A O   1 
ATOM   1743  C CB  . PRO A 1 238 ? -29.331  -7.486  23.838  1.00 71.57  ? 445 PRO A CB  1 
ATOM   1744  C CG  . PRO A 1 238 ? -29.836  -6.224  24.432  1.00 80.40  ? 445 PRO A CG  1 
ATOM   1745  C CD  . PRO A 1 238 ? -30.935  -6.612  25.394  1.00 83.75  ? 445 PRO A CD  1 
ATOM   1746  N N   . ALA A 1 239 ? -29.791  -10.470 22.764  1.00 63.55  ? 446 ALA A N   1 
ATOM   1747  C CA  . ALA A 1 239 ? -29.685  -11.922 22.697  1.00 58.16  ? 446 ALA A CA  1 
ATOM   1748  C C   . ALA A 1 239 ? -28.236  -12.365 22.714  1.00 57.77  ? 446 ALA A C   1 
ATOM   1749  O O   . ALA A 1 239 ? -27.767  -13.027 21.779  1.00 55.95  ? 446 ALA A O   1 
ATOM   1750  C CB  . ALA A 1 239 ? -30.389  -12.463 21.454  1.00 55.39  ? 446 ALA A CB  1 
ATOM   1751  N N   . ASN A 1 240 ? -27.524  -12.008 23.779  1.00 56.34  ? 447 ASN A N   1 
ATOM   1752  C CA  . ASN A 1 240 ? -26.150  -12.430 23.970  1.00 53.99  ? 447 ASN A CA  1 
ATOM   1753  C C   . ASN A 1 240 ? -26.121  -13.602 24.931  1.00 53.95  ? 447 ASN A C   1 
ATOM   1754  O O   . ASN A 1 240 ? -26.791  -13.581 25.968  1.00 58.41  ? 447 ASN A O   1 
ATOM   1755  C CB  . ASN A 1 240 ? -25.293  -11.283 24.482  1.00 65.24  ? 447 ASN A CB  1 
ATOM   1756  C CG  . ASN A 1 240 ? -25.159  -10.181 23.459  1.00 65.83  ? 447 ASN A CG  1 
ATOM   1757  O OD1 . ASN A 1 240 ? -25.628  -10.314 22.325  1.00 71.86  ? 447 ASN A OD1 1 
ATOM   1758  N ND2 . ASN A 1 240 ? -24.508  -9.097  23.838  1.00 78.42  ? 447 ASN A ND2 1 
ATOM   1759  N N   . TYR A 1 241 ? -25.370  -14.616 24.517  1.00 49.81  ? 448 TYR A N   1 
ATOM   1760  C CA  . TYR A 1 241 ? -25.322  -15.875 25.278  1.00 55.52  ? 448 TYR A CA  1 
ATOM   1761  C C   . TYR A 1 241 ? -23.887  -16.136 25.705  1.00 57.86  ? 448 TYR A C   1 
ATOM   1762  O O   . TYR A 1 241 ? -22.972  -15.913 24.914  1.00 61.36  ? 448 TYR A O   1 
ATOM   1763  C CB  . TYR A 1 241 ? -25.855  -16.995 24.387  1.00 54.77  ? 448 TYR A CB  1 
ATOM   1764  C CG  . TYR A 1 241 ? -27.354  -17.035 24.319  1.00 56.11  ? 448 TYR A CG  1 
ATOM   1765  C CD1 . TYR A 1 241 ? -28.065  -16.058 23.645  1.00 53.49  ? 448 TYR A CD1 1 
ATOM   1766  C CD2 . TYR A 1 241 ? -28.060  -18.036 24.954  1.00 55.21  ? 448 TYR A CD2 1 
ATOM   1767  C CE1 . TYR A 1 241 ? -29.445  -16.064 23.606  1.00 49.97  ? 448 TYR A CE1 1 
ATOM   1768  C CE2 . TYR A 1 241 ? -29.440  -18.062 24.920  1.00 50.62  ? 448 TYR A CE2 1 
ATOM   1769  C CZ  . TYR A 1 241 ? -30.130  -17.076 24.243  1.00 47.49  ? 448 TYR A CZ  1 
ATOM   1770  O OH  . TYR A 1 241 ? -31.486  -17.084 24.219  1.00 45.47  ? 448 TYR A OH  1 
ATOM   1771  N N   . ILE A 1 242 ? -23.712  -16.603 26.934  1.00 54.67  ? 449 ILE A N   1 
ATOM   1772  C CA  . ILE A 1 242 ? -22.376  -16.844 27.472  1.00 56.12  ? 449 ILE A CA  1 
ATOM   1773  C C   . ILE A 1 242 ? -22.163  -18.344 27.553  1.00 52.93  ? 449 ILE A C   1 
ATOM   1774  O O   . ILE A 1 242 ? -23.068  -19.073 27.960  1.00 54.18  ? 449 ILE A O   1 
ATOM   1775  C CB  . ILE A 1 242 ? -22.194  -16.182 28.855  1.00 53.02  ? 449 ILE A CB  1 
ATOM   1776  C CG1 . ILE A 1 242 ? -22.570  -14.693 28.800  1.00 62.86  ? 449 ILE A CG1 1 
ATOM   1777  C CG2 . ILE A 1 242 ? -20.797  -16.342 29.329  1.00 60.48  ? 449 ILE A CG2 1 
ATOM   1778  C CD1 . ILE A 1 242 ? -21.468  -13.726 28.268  1.00 66.31  ? 449 ILE A CD1 1 
ATOM   1779  N N   . LEU A 1 243 ? -20.971  -18.800 27.179  1.00 50.83  ? 450 LEU A N   1 
ATOM   1780  C CA  . LEU A 1 243 ? -20.706  -20.227 27.076  1.00 43.94  ? 450 LEU A CA  1 
ATOM   1781  C C   . LEU A 1 243 ? -20.658  -20.843 28.457  1.00 48.70  ? 450 LEU A C   1 
ATOM   1782  O O   . LEU A 1 243 ? -19.975  -20.331 29.344  1.00 60.58  ? 450 LEU A O   1 
ATOM   1783  C CB  . LEU A 1 243 ? -19.384  -20.486 26.361  1.00 46.67  ? 450 LEU A CB  1 
ATOM   1784  C CG  . LEU A 1 243 ? -19.054  -21.968 26.368  1.00 42.14  ? 450 LEU A CG  1 
ATOM   1785  C CD1 . LEU A 1 243 ? -20.087  -22.655 25.494  1.00 50.56  ? 450 LEU A CD1 1 
ATOM   1786  C CD2 . LEU A 1 243 ? -17.699  -22.222 25.832  1.00 43.48  ? 450 LEU A CD2 1 
ATOM   1787  N N   . HIS A 1 244 ? -21.413  -21.916 28.673  1.00 45.26  ? 451 HIS A N   1 
ATOM   1788  C CA  . HIS A 1 244 ? -21.452  -22.568 30.002  1.00 43.59  ? 451 HIS A CA  1 
ATOM   1789  C C   . HIS A 1 244 ? -20.824  -23.951 29.929  1.00 52.20  ? 451 HIS A C   1 
ATOM   1790  O O   . HIS A 1 244 ? -19.973  -24.241 30.774  1.00 56.84  ? 451 HIS A O   1 
ATOM   1791  C CB  . HIS A 1 244 ? -22.888  -22.680 30.500  1.00 46.81  ? 451 HIS A CB  1 
ATOM   1792  C CG  . HIS A 1 244 ? -23.038  -23.193 31.891  1.00 49.07  ? 451 HIS A CG  1 
ATOM   1793  N ND1 . HIS A 1 244 ? -23.751  -24.336 32.176  1.00 48.08  ? 451 HIS A ND1 1 
ATOM   1794  C CD2 . HIS A 1 244 ? -22.614  -22.705 33.073  1.00 50.69  ? 451 HIS A CD2 1 
ATOM   1795  C CE1 . HIS A 1 244 ? -23.742  -24.542 33.475  1.00 56.30  ? 451 HIS A CE1 1 
ATOM   1796  N NE2 . HIS A 1 244 ? -23.053  -23.557 34.045  1.00 54.26  ? 451 HIS A NE2 1 
ATOM   1797  N N   . ALA A 1 245 ? -21.228  -24.771 28.969  1.00 41.71  ? 452 ALA A N   1 
ATOM   1798  C CA  . ALA A 1 245 ? -20.722  -26.156 28.980  1.00 45.88  ? 452 ALA A CA  1 
ATOM   1799  C C   . ALA A 1 245 ? -20.271  -26.645 27.609  1.00 51.29  ? 452 ALA A C   1 
ATOM   1800  O O   . ALA A 1 245 ? -20.843  -26.223 26.605  1.00 52.39  ? 452 ALA A O   1 
ATOM   1801  C CB  . ALA A 1 245 ? -21.771  -27.066 29.542  1.00 49.48  ? 452 ALA A CB  1 
ATOM   1802  N N   . VAL A 1 246 ? -19.267  -27.517 27.605  1.00 54.85  ? 453 VAL A N   1 
ATOM   1803  C CA  . VAL A 1 246 ? -18.745  -28.129 26.356  1.00 57.29  ? 453 VAL A CA  1 
ATOM   1804  C C   . VAL A 1 246 ? -18.734  -29.638 26.596  1.00 55.82  ? 453 VAL A C   1 
ATOM   1805  O O   . VAL A 1 246 ? -17.864  -30.109 27.329  1.00 54.41  ? 453 VAL A O   1 
ATOM   1806  C CB  . VAL A 1 246 ? -17.348  -27.589 25.995  1.00 55.86  ? 453 VAL A CB  1 
ATOM   1807  C CG1 . VAL A 1 246 ? -16.873  -28.092 24.649  1.00 43.15  ? 453 VAL A CG1 1 
ATOM   1808  C CG2 . VAL A 1 246 ? -17.267  -26.073 26.046  1.00 50.71  ? 453 VAL A CG2 1 
ATOM   1809  N N   . LEU A 1 247 ? -19.721  -30.330 26.033  1.00 51.40  ? 454 LEU A N   1 
ATOM   1810  C CA  . LEU A 1 247 ? -19.812  -31.801 26.162  1.00 49.41  ? 454 LEU A CA  1 
ATOM   1811  C C   . LEU A 1 247 ? -18.927  -32.376 25.069  1.00 58.02  ? 454 LEU A C   1 
ATOM   1812  O O   . LEU A 1 247 ? -19.366  -32.429 23.917  1.00 58.02  ? 454 LEU A O   1 
ATOM   1813  C CB  . LEU A 1 247 ? -21.278  -32.223 26.076  1.00 43.82  ? 454 LEU A CB  1 
ATOM   1814  C CG  . LEU A 1 247 ? -22.122  -31.822 27.284  1.00 53.35  ? 454 LEU A CG  1 
ATOM   1815  C CD1 . LEU A 1 247 ? -22.884  -30.531 27.032  1.00 45.47  ? 454 LEU A CD1 1 
ATOM   1816  C CD2 . LEU A 1 247 ? -23.076  -32.931 27.679  1.00 57.71  ? 454 LEU A CD2 1 
ATOM   1817  N N   . VAL A 1 248 ? -17.721  -32.785 25.440  1.00 66.97  ? 455 VAL A N   1 
ATOM   1818  C CA  . VAL A 1 248 ? -16.709  -33.220 24.480  1.00 60.16  ? 455 VAL A CA  1 
ATOM   1819  C C   . VAL A 1 248 ? -16.792  -34.720 24.305  1.00 55.22  ? 455 VAL A C   1 
ATOM   1820  O O   . VAL A 1 248 ? -16.792  -35.469 25.287  1.00 64.53  ? 455 VAL A O   1 
ATOM   1821  C CB  . VAL A 1 248 ? -15.299  -32.819 24.943  1.00 59.70  ? 455 VAL A CB  1 
ATOM   1822  C CG1 . VAL A 1 248 ? -14.246  -33.525 24.094  1.00 58.23  ? 455 VAL A CG1 1 
ATOM   1823  C CG2 . VAL A 1 248 ? -15.137  -31.320 24.866  1.00 57.71  ? 455 VAL A CG2 1 
ATOM   1824  N N   . HIS A 1 249 ? -16.850  -35.139 23.036  1.00 52.54  ? 456 HIS A N   1 
ATOM   1825  C CA  . HIS A 1 249 ? -16.842  -36.578 22.678  1.00 56.54  ? 456 HIS A CA  1 
ATOM   1826  C C   . HIS A 1 249 ? -15.480  -36.934 22.084  1.00 62.39  ? 456 HIS A C   1 
ATOM   1827  O O   . HIS A 1 249 ? -14.877  -36.082 21.425  1.00 60.73  ? 456 HIS A O   1 
ATOM   1828  C CB  . HIS A 1 249 ? -17.957  -36.891 21.675  1.00 52.28  ? 456 HIS A CB  1 
ATOM   1829  C CG  . HIS A 1 249 ? -17.883  -38.236 21.035  1.00 56.59  ? 456 HIS A CG  1 
ATOM   1830  N ND1 . HIS A 1 249 ? -17.449  -38.409 19.740  1.00 58.05  ? 456 HIS A ND1 1 
ATOM   1831  C CD2 . HIS A 1 249 ? -18.187  -39.465 21.497  1.00 56.11  ? 456 HIS A CD2 1 
ATOM   1832  C CE1 . HIS A 1 249 ? -17.483  -39.687 19.433  1.00 59.24  ? 456 HIS A CE1 1 
ATOM   1833  N NE2 . HIS A 1 249 ? -17.929  -40.353 20.492  1.00 56.59  ? 456 HIS A NE2 1 
ATOM   1834  N N   . SER A 1 250 ? -15.000  -38.155 22.327  1.00 66.21  ? 457 SER A N   1 
ATOM   1835  C CA  . SER A 1 250 ? -13.715  -38.634 21.758  1.00 63.79  ? 457 SER A CA  1 
ATOM   1836  C C   . SER A 1 250 ? -13.890  -40.057 21.230  1.00 59.28  ? 457 SER A C   1 
ATOM   1837  O O   . SER A 1 250 ? -14.172  -40.922 22.039  1.00 64.77  ? 457 SER A O   1 
ATOM   1838  C CB  . SER A 1 250 ? -12.620  -38.591 22.780  1.00 68.05  ? 457 SER A CB  1 
ATOM   1839  O OG  . SER A 1 250 ? -12.585  -37.342 23.450  1.00 72.72  ? 457 SER A OG  1 
ATOM   1840  N N   . GLY A 1 251 ? -13.686  -40.285 19.934  1.00 59.63  ? 458 GLY A N   1 
ATOM   1841  C CA  . GLY A 1 251 ? -13.893  -41.599 19.361  1.00 63.49  ? 458 GLY A CA  1 
ATOM   1842  C C   . GLY A 1 251 ? -14.339  -41.484 17.916  1.00 70.26  ? 458 GLY A C   1 
ATOM   1843  O O   . GLY A 1 251 ? -13.961  -40.543 17.221  1.00 70.98  ? 458 GLY A O   1 
ATOM   1844  N N   . ASP A 1 252 ? -15.150  -42.459 17.491  1.00 69.79  ? 459 ASP A N   1 
ATOM   1845  C CA  . ASP A 1 252 ? -15.615  -42.543 16.104  1.00 70.76  ? 459 ASP A CA  1 
ATOM   1846  C C   . ASP A 1 252 ? -17.083  -42.967 15.962  1.00 82.50  ? 459 ASP A C   1 
ATOM   1847  O O   . ASP A 1 252 ? -18.011  -42.233 16.294  1.00 78.24  ? 459 ASP A O   1 
ATOM   1848  C CB  . ASP A 1 252 ? -14.758  -43.535 15.340  1.00 73.99  ? 459 ASP A CB  1 
ATOM   1849  C CG  . ASP A 1 252 ? -14.449  -44.750 16.159  1.00 87.09  ? 459 ASP A CG  1 
ATOM   1850  O OD1 . ASP A 1 252 ? -15.336  -45.160 16.946  1.00 95.44  ? 459 ASP A OD1 1 
ATOM   1851  O OD2 . ASP A 1 252 ? -13.326  -45.284 16.033  1.00 89.01  ? 459 ASP A OD2 1 
ATOM   1852  N N   . GLY A 1 255 ? -18.296  -45.828 18.769  1.00 106.03 ? 462 GLY A N   1 
ATOM   1853  C CA  . GLY A 1 255 ? -18.061  -45.725 20.200  1.00 91.82  ? 462 GLY A CA  1 
ATOM   1854  C C   . GLY A 1 255 ? -16.888  -44.824 20.574  1.00 78.94  ? 462 GLY A C   1 
ATOM   1855  O O   . GLY A 1 255 ? -16.081  -44.462 19.712  1.00 80.55  ? 462 GLY A O   1 
ATOM   1856  N N   . GLY A 1 256 ? -16.797  -44.477 21.861  1.00 64.96  ? 463 GLY A N   1 
ATOM   1857  C CA  . GLY A 1 256 ? -15.788  -43.540 22.340  1.00 61.39  ? 463 GLY A CA  1 
ATOM   1858  C C   . GLY A 1 256 ? -16.017  -43.155 23.799  1.00 65.77  ? 463 GLY A C   1 
ATOM   1859  O O   . GLY A 1 256 ? -16.615  -43.917 24.570  1.00 67.19  ? 463 GLY A O   1 
ATOM   1860  N N   . HIS A 1 257 ? -15.566  -41.958 24.187  1.00 60.64  ? 464 HIS A N   1 
ATOM   1861  C CA  . HIS A 1 257 ? -15.708  -41.482 25.590  1.00 60.06  ? 464 HIS A CA  1 
ATOM   1862  C C   . HIS A 1 257 ? -16.292  -40.071 25.637  1.00 60.16  ? 464 HIS A C   1 
ATOM   1863  O O   . HIS A 1 257 ? -16.004  -39.287 24.728  1.00 59.78  ? 464 HIS A O   1 
ATOM   1864  C CB  . HIS A 1 257 ? -14.355  -41.493 26.301  1.00 60.94  ? 464 HIS A CB  1 
ATOM   1865  C CG  . HIS A 1 257 ? -14.430  -41.270 27.771  1.00 51.52  ? 464 HIS A CG  1 
ATOM   1866  N ND1 . HIS A 1 257 ? -14.810  -42.261 28.643  1.00 55.29  ? 464 HIS A ND1 1 
ATOM   1867  C CD2 . HIS A 1 257 ? -14.174  -40.180 28.520  1.00 53.71  ? 464 HIS A CD2 1 
ATOM   1868  C CE1 . HIS A 1 257 ? -14.789  -41.790 29.869  1.00 53.34  ? 464 HIS A CE1 1 
ATOM   1869  N NE2 . HIS A 1 257 ? -14.413  -40.517 29.819  1.00 53.61  ? 464 HIS A NE2 1 
ATOM   1870  N N   . TYR A 1 258 ? -17.043  -39.765 26.692  1.00 55.20  ? 465 TYR A N   1 
ATOM   1871  C CA  . TYR A 1 258 ? -17.686  -38.439 26.827  1.00 60.01  ? 465 TYR A CA  1 
ATOM   1872  C C   . TYR A 1 258 ? -17.167  -37.704 28.062  1.00 62.11  ? 465 TYR A C   1 
ATOM   1873  O O   . TYR A 1 258 ? -17.023  -38.327 29.122  1.00 64.52  ? 465 TYR A O   1 
ATOM   1874  C CB  . TYR A 1 258 ? -19.197  -38.606 26.935  1.00 56.92  ? 465 TYR A CB  1 
ATOM   1875  C CG  . TYR A 1 258 ? -19.955  -38.496 25.645  1.00 54.84  ? 465 TYR A CG  1 
ATOM   1876  C CD1 . TYR A 1 258 ? -20.078  -37.283 24.996  1.00 54.94  ? 465 TYR A CD1 1 
ATOM   1877  C CD2 . TYR A 1 258 ? -20.567  -39.603 25.090  1.00 47.05  ? 465 TYR A CD2 1 
ATOM   1878  C CE1 . TYR A 1 258 ? -20.783  -37.174 23.813  1.00 44.76  ? 465 TYR A CE1 1 
ATOM   1879  C CE2 . TYR A 1 258 ? -21.278  -39.512 23.910  1.00 48.06  ? 465 TYR A CE2 1 
ATOM   1880  C CZ  . TYR A 1 258 ? -21.384  -38.293 23.272  1.00 46.08  ? 465 TYR A CZ  1 
ATOM   1881  O OH  . TYR A 1 258 ? -22.087  -38.196 22.115  1.00 55.02  ? 465 TYR A OH  1 
ATOM   1882  N N   . VAL A 1 259 ? -16.923  -36.405 27.926  1.00 58.43  ? 466 VAL A N   1 
ATOM   1883  C CA  . VAL A 1 259 ? -16.426  -35.552 29.039  1.00 58.02  ? 466 VAL A CA  1 
ATOM   1884  C C   . VAL A 1 259 ? -17.202  -34.240 28.936  1.00 60.71  ? 466 VAL A C   1 
ATOM   1885  O O   . VAL A 1 259 ? -17.709  -33.953 27.856  1.00 66.15  ? 466 VAL A O   1 
ATOM   1886  C CB  . VAL A 1 259 ? -14.908  -35.330 28.890  1.00 59.07  ? 466 VAL A CB  1 
ATOM   1887  C CG1 . VAL A 1 259 ? -14.350  -34.232 29.772  1.00 63.31  ? 466 VAL A CG1 1 
ATOM   1888  C CG2 . VAL A 1 259 ? -14.097  -36.599 29.065  1.00 61.90  ? 466 VAL A CG2 1 
ATOM   1889  N N   . VAL A 1 260 ? -17.368  -33.530 30.052  1.00 52.20  ? 467 VAL A N   1 
ATOM   1890  C CA  . VAL A 1 260 ? -18.022  -32.193 30.013  1.00 56.55  ? 467 VAL A CA  1 
ATOM   1891  C C   . VAL A 1 260 ? -17.100  -31.153 30.656  1.00 62.82  ? 467 VAL A C   1 
ATOM   1892  O O   . VAL A 1 260 ? -16.551  -31.417 31.731  1.00 61.06  ? 467 VAL A O   1 
ATOM   1893  C CB  . VAL A 1 260 ? -19.428  -32.203 30.640  1.00 55.82  ? 467 VAL A CB  1 
ATOM   1894  C CG1 . VAL A 1 260 ? -19.446  -32.673 32.082  1.00 53.50  ? 467 VAL A CG1 1 
ATOM   1895  C CG2 . VAL A 1 260 ? -20.128  -30.866 30.488  1.00 54.70  ? 467 VAL A CG2 1 
ATOM   1896  N N   . TYR A 1 261 ? -16.886  -30.038 29.966  1.00 61.70  ? 468 TYR A N   1 
ATOM   1897  C CA  . TYR A 1 261 ? -16.091  -28.923 30.524  1.00 56.68  ? 468 TYR A CA  1 
ATOM   1898  C C   . TYR A 1 261 ? -17.101  -27.868 30.958  1.00 55.99  ? 468 TYR A C   1 
ATOM   1899  O O   . TYR A 1 261 ? -17.999  -27.578 30.174  1.00 59.06  ? 468 TYR A O   1 
ATOM   1900  C CB  . TYR A 1 261 ? -15.120  -28.394 29.471  1.00 58.05  ? 468 TYR A CB  1 
ATOM   1901  C CG  . TYR A 1 261 ? -13.922  -29.257 29.173  1.00 58.48  ? 468 TYR A CG  1 
ATOM   1902  C CD1 . TYR A 1 261 ? -14.024  -30.370 28.358  1.00 56.85  ? 468 TYR A CD1 1 
ATOM   1903  C CD2 . TYR A 1 261 ? -12.674  -28.938 29.677  1.00 59.81  ? 468 TYR A CD2 1 
ATOM   1904  C CE1 . TYR A 1 261 ? -12.922  -31.155 28.068  1.00 60.86  ? 468 TYR A CE1 1 
ATOM   1905  C CE2 . TYR A 1 261 ? -11.559  -29.704 29.388  1.00 59.01  ? 468 TYR A CE2 1 
ATOM   1906  C CZ  . TYR A 1 261 ? -11.685  -30.820 28.584  1.00 57.81  ? 468 TYR A CZ  1 
ATOM   1907  O OH  . TYR A 1 261 ? -10.596  -31.588 28.301  1.00 55.26  ? 468 TYR A OH  1 
ATOM   1908  N N   . LEU A 1 262 ? -16.946  -27.295 32.147  1.00 51.38  ? 469 LEU A N   1 
ATOM   1909  C CA  . LEU A 1 262 ? -17.997  -26.387 32.661  1.00 54.76  ? 469 LEU A CA  1 
ATOM   1910  C C   . LEU A 1 262 ? -17.443  -25.222 33.477  1.00 59.75  ? 469 LEU A C   1 
ATOM   1911  O O   . LEU A 1 262 ? -16.502  -25.452 34.229  1.00 61.06  ? 469 LEU A O   1 
ATOM   1912  C CB  . LEU A 1 262 ? -18.869  -27.226 33.598  1.00 52.49  ? 469 LEU A CB  1 
ATOM   1913  C CG  . LEU A 1 262 ? -20.102  -27.920 33.032  1.00 52.99  ? 469 LEU A CG  1 
ATOM   1914  C CD1 . LEU A 1 262 ? -20.300  -29.253 33.729  1.00 51.96  ? 469 LEU A CD1 1 
ATOM   1915  C CD2 . LEU A 1 262 ? -21.328  -27.057 33.242  1.00 53.19  ? 469 LEU A CD2 1 
ATOM   1916  N N   . ASN A 1 263 ? -18.003  -24.019 33.328  1.00 58.05  ? 470 ASN A N   1 
ATOM   1917  C CA  . ASN A 1 263 ? -17.691  -22.879 34.235  1.00 61.99  ? 470 ASN A CA  1 
ATOM   1918  C C   . ASN A 1 263 ? -18.997  -22.703 35.004  1.00 59.93  ? 470 ASN A C   1 
ATOM   1919  O O   . ASN A 1 263 ? -19.771  -21.798 34.678  1.00 53.22  ? 470 ASN A O   1 
ATOM   1920  C CB  . ASN A 1 263 ? -17.186  -21.611 33.536  1.00 61.28  ? 470 ASN A CB  1 
ATOM   1921  C CG  . ASN A 1 263 ? -18.097  -21.020 32.484  1.00 65.01  ? 470 ASN A CG  1 
ATOM   1922  O OD1 . ASN A 1 263 ? -18.698  -21.741 31.701  1.00 66.17  ? 470 ASN A OD1 1 
ATOM   1923  N ND2 . ASN A 1 263 ? -18.211  -19.705 32.469  1.00 64.99  ? 470 ASN A ND2 1 
ATOM   1924  N N   . PRO A 1 264 ? -19.292  -23.534 36.023  1.00 61.36  ? 471 PRO A N   1 
ATOM   1925  C CA  . PRO A 1 264 ? -20.635  -23.531 36.628  1.00 55.26  ? 471 PRO A CA  1 
ATOM   1926  C C   . PRO A 1 264 ? -21.157  -22.161 36.980  1.00 54.64  ? 471 PRO A C   1 
ATOM   1927  O O   . PRO A 1 264 ? -22.313  -21.867 36.670  1.00 61.98  ? 471 PRO A O   1 
ATOM   1928  C CB  . PRO A 1 264 ? -20.453  -24.412 37.871  1.00 52.60  ? 471 PRO A CB  1 
ATOM   1929  C CG  . PRO A 1 264 ? -19.362  -25.365 37.486  1.00 56.85  ? 471 PRO A CG  1 
ATOM   1930  C CD  . PRO A 1 264 ? -18.418  -24.571 36.609  1.00 58.23  ? 471 PRO A CD  1 
ATOM   1931  N N   . LYS A 1 265 ? -20.344  -21.300 37.583  1.00 57.90  ? 472 LYS A N   1 
ATOM   1932  C CA  . LYS A 1 265 ? -20.854  -20.030 38.093  1.00 65.87  ? 472 LYS A CA  1 
ATOM   1933  C C   . LYS A 1 265 ? -21.011  -18.964 37.011  1.00 66.94  ? 472 LYS A C   1 
ATOM   1934  O O   . LYS A 1 265 ? -21.420  -17.836 37.332  1.00 62.33  ? 472 LYS A O   1 
ATOM   1935  C CB  . LYS A 1 265 ? -19.943  -19.514 39.221  1.00 70.56  ? 472 LYS A CB  1 
ATOM   1936  C CG  . LYS A 1 265 ? -20.248  -20.109 40.610  1.00 74.55  ? 472 LYS A CG  1 
ATOM   1937  C CD  . LYS A 1 265 ? -19.196  -19.765 41.674  1.00 76.67  ? 472 LYS A CD  1 
ATOM   1938  C CE  . LYS A 1 265 ? -19.869  -19.442 43.008  1.00 83.19  ? 472 LYS A CE  1 
ATOM   1939  N NZ  . LYS A 1 265 ? -19.391  -20.287 44.143  1.00 92.87  ? 472 LYS A NZ  1 
ATOM   1940  N N   . GLY A 1 266 ? -20.723  -19.291 35.747  1.00 62.03  ? 473 GLY A N   1 
ATOM   1941  C CA  . GLY A 1 266 ? -20.717  -18.299 34.693  1.00 64.65  ? 473 GLY A CA  1 
ATOM   1942  C C   . GLY A 1 266 ? -19.605  -17.277 34.783  1.00 69.56  ? 473 GLY A C   1 
ATOM   1943  O O   . GLY A 1 266 ? -19.569  -16.358 33.956  1.00 65.00  ? 473 GLY A O   1 
ATOM   1944  N N   . ASP A 1 267 ? -18.692  -17.418 35.754  1.00 72.62  ? 474 ASP A N   1 
ATOM   1945  C CA  . ASP A 1 267 ? -17.617  -16.471 36.023  1.00 68.94  ? 474 ASP A CA  1 
ATOM   1946  C C   . ASP A 1 267 ? -16.426  -16.657 35.102  1.00 71.09  ? 474 ASP A C   1 
ATOM   1947  O O   . ASP A 1 267 ? -15.620  -15.725 34.958  1.00 72.82  ? 474 ASP A O   1 
ATOM   1948  C CB  . ASP A 1 267 ? -17.151  -16.633 37.463  1.00 58.62  ? 474 ASP A CB  1 
ATOM   1949  C CG  . ASP A 1 267 ? -16.798  -18.068 37.790  1.00 68.86  ? 474 ASP A CG  1 
ATOM   1950  O OD1 . ASP A 1 267 ? -16.840  -18.943 36.880  1.00 59.45  ? 474 ASP A OD1 1 
ATOM   1951  O OD2 . ASP A 1 267 ? -16.499  -18.320 38.976  1.00 81.62  ? 474 ASP A OD2 1 
ATOM   1952  N N   . GLY A 1 268 ? -16.280  -17.839 34.515  1.00 58.94  ? 475 GLY A N   1 
ATOM   1953  C CA  . GLY A 1 268 ? -15.176  -18.116 33.635  1.00 61.70  ? 475 GLY A CA  1 
ATOM   1954  C C   . GLY A 1 268 ? -14.070  -18.929 34.249  1.00 62.60  ? 475 GLY A C   1 
ATOM   1955  O O   . GLY A 1 268 ? -12.999  -19.032 33.645  1.00 58.53  ? 475 GLY A O   1 
ATOM   1956  N N   . LYS A 1 269 ? -14.287  -19.504 35.429  1.00 65.77  ? 476 LYS A N   1 
ATOM   1957  C CA  . LYS A 1 269 ? -13.320  -20.394 36.066  1.00 68.03  ? 476 LYS A CA  1 
ATOM   1958  C C   . LYS A 1 269 ? -13.787  -21.831 35.823  1.00 70.22  ? 476 LYS A C   1 
ATOM   1959  O O   . LYS A 1 269 ? -14.692  -22.329 36.499  1.00 71.98  ? 476 LYS A O   1 
ATOM   1960  C CB  . LYS A 1 269 ? -13.189  -20.067 37.553  1.00 65.72  ? 476 LYS A CB  1 
ATOM   1961  N N   . TRP A 1 270 ? -13.160  -22.498 34.860  1.00 68.75  ? 477 TRP A N   1 
ATOM   1962  C CA  . TRP A 1 270 ? -13.675  -23.745 34.312  1.00 65.84  ? 477 TRP A CA  1 
ATOM   1963  C C   . TRP A 1 270 ? -13.107  -24.950 35.036  1.00 64.94  ? 477 TRP A C   1 
ATOM   1964  O O   . TRP A 1 270 ? -12.017  -24.895 35.597  1.00 70.82  ? 477 TRP A O   1 
ATOM   1965  C CB  . TRP A 1 270 ? -13.325  -23.868 32.831  1.00 65.21  ? 477 TRP A CB  1 
ATOM   1966  C CG  . TRP A 1 270 ? -14.041  -22.891 31.962  1.00 68.49  ? 477 TRP A CG  1 
ATOM   1967  C CD1 . TRP A 1 270 ? -13.886  -21.528 31.941  1.00 68.32  ? 477 TRP A CD1 1 
ATOM   1968  C CD2 . TRP A 1 270 ? -15.036  -23.197 30.984  1.00 66.74  ? 477 TRP A CD2 1 
ATOM   1969  N NE1 . TRP A 1 270 ? -14.730  -20.967 31.008  1.00 66.31  ? 477 TRP A NE1 1 
ATOM   1970  C CE2 . TRP A 1 270 ? -15.447  -21.969 30.405  1.00 67.19  ? 477 TRP A CE2 1 
ATOM   1971  C CE3 . TRP A 1 270 ? -15.635  -24.382 30.555  1.00 58.64  ? 477 TRP A CE3 1 
ATOM   1972  C CZ2 . TRP A 1 270 ? -16.413  -21.900 29.409  1.00 52.36  ? 477 TRP A CZ2 1 
ATOM   1973  C CZ3 . TRP A 1 270 ? -16.584  -24.309 29.572  1.00 61.74  ? 477 TRP A CZ3 1 
ATOM   1974  C CH2 . TRP A 1 270 ? -16.969  -23.075 29.009  1.00 58.00  ? 477 TRP A CH2 1 
ATOM   1975  N N   . CYS A 1 271 ? -13.835  -26.059 34.976  1.00 62.54  ? 478 CYS A N   1 
ATOM   1976  C CA  . CYS A 1 271 ? -13.330  -27.340 35.438  1.00 59.01  ? 478 CYS A CA  1 
ATOM   1977  C C   . CYS A 1 271 ? -13.662  -28.397 34.396  1.00 58.30  ? 478 CYS A C   1 
ATOM   1978  O O   . CYS A 1 271 ? -14.501  -28.198 33.520  1.00 53.34  ? 478 CYS A O   1 
ATOM   1979  C CB  . CYS A 1 271 ? -13.923  -27.728 36.793  1.00 53.62  ? 478 CYS A CB  1 
ATOM   1980  S SG  . CYS A 1 271 ? -13.754  -26.417 37.972  1.00 58.15  ? 478 CYS A SG  1 
ATOM   1981  N N   . LYS A 1 272 ? -12.974  -29.522 34.487  1.00 56.95  ? 479 LYS A N   1 
ATOM   1982  C CA  . LYS A 1 272 ? -13.200  -30.644 33.595  1.00 57.21  ? 479 LYS A CA  1 
ATOM   1983  C C   . LYS A 1 272 ? -13.765  -31.804 34.395  1.00 67.20  ? 479 LYS A C   1 
ATOM   1984  O O   . LYS A 1 272 ? -13.277  -32.118 35.487  1.00 72.13  ? 479 LYS A O   1 
ATOM   1985  C CB  . LYS A 1 272 ? -11.913  -31.078 32.890  1.00 57.74  ? 479 LYS A CB  1 
ATOM   1986  C CG  . LYS A 1 272 ? -12.088  -32.305 32.026  1.00 52.82  ? 479 LYS A CG  1 
ATOM   1987  C CD  . LYS A 1 272 ? -10.742  -32.901 31.622  1.00 59.67  ? 479 LYS A CD  1 
ATOM   1988  C CE  . LYS A 1 272 ? -10.901  -34.261 30.915  1.00 63.50  ? 479 LYS A CE  1 
ATOM   1989  N NZ  . LYS A 1 272 ? -9.846   -34.453 29.873  1.00 62.79  ? 479 LYS A NZ  1 
ATOM   1990  N N   . PHE A 1 273 ? -14.787  -32.440 33.842  1.00 66.30  ? 480 PHE A N   1 
ATOM   1991  C CA  . PHE A 1 273 ? -15.513  -33.504 34.522  1.00 62.69  ? 480 PHE A CA  1 
ATOM   1992  C C   . PHE A 1 273 ? -15.347  -34.751 33.672  1.00 64.85  ? 480 PHE A C   1 
ATOM   1993  O O   . PHE A 1 273 ? -16.022  -34.921 32.650  1.00 64.94  ? 480 PHE A O   1 
ATOM   1994  C CB  . PHE A 1 273 ? -16.978  -33.135 34.716  1.00 62.02  ? 480 PHE A CB  1 
ATOM   1995  C CG  . PHE A 1 273 ? -17.187  -31.951 35.615  1.00 55.02  ? 480 PHE A CG  1 
ATOM   1996  C CD1 . PHE A 1 273 ? -16.793  -30.690 35.222  1.00 51.93  ? 480 PHE A CD1 1 
ATOM   1997  C CD2 . PHE A 1 273 ? -17.785  -32.106 36.846  1.00 52.22  ? 480 PHE A CD2 1 
ATOM   1998  C CE1 . PHE A 1 273 ? -16.976  -29.607 36.041  1.00 52.36  ? 480 PHE A CE1 1 
ATOM   1999  C CE2 . PHE A 1 273 ? -17.977  -31.034 37.668  1.00 54.01  ? 480 PHE A CE2 1 
ATOM   2000  C CZ  . PHE A 1 273 ? -17.572  -29.774 37.262  1.00 56.92  ? 480 PHE A CZ  1 
ATOM   2001  N N   . ASP A 1 274 ? -14.403  -35.595 34.077  1.00 67.81  ? 481 ASP A N   1 
ATOM   2002  C CA  . ASP A 1 274 ? -14.186  -36.889 33.385  1.00 68.81  ? 481 ASP A CA  1 
ATOM   2003  C C   . ASP A 1 274 ? -14.660  -37.962 34.351  1.00 69.73  ? 481 ASP A C   1 
ATOM   2004  O O   . ASP A 1 274 ? -13.842  -38.418 35.163  1.00 73.40  ? 481 ASP A O   1 
ATOM   2005  C CB  . ASP A 1 274 ? -12.720  -37.080 32.986  1.00 69.78  ? 481 ASP A CB  1 
ATOM   2006  C CG  . ASP A 1 274 ? -12.452  -38.212 32.011  1.00 70.75  ? 481 ASP A CG  1 
ATOM   2007  O OD1 . ASP A 1 274 ? -13.094  -39.267 32.137  1.00 59.95  ? 481 ASP A OD1 1 
ATOM   2008  O OD2 . ASP A 1 274 ? -11.581  -38.032 31.141  1.00 66.65  ? 481 ASP A OD2 1 
ATOM   2009  N N   . ASP A 1 275 ? -15.938  -38.309 34.277  1.00 71.21  ? 482 ASP A N   1 
ATOM   2010  C CA  . ASP A 1 275 ? -16.526  -39.327 35.180  1.00 65.40  ? 482 ASP A CA  1 
ATOM   2011  C C   . ASP A 1 275 ? -16.118  -39.011 36.625  1.00 71.63  ? 482 ASP A C   1 
ATOM   2012  O O   . ASP A 1 275 ? -16.611  -38.001 37.142  1.00 71.67  ? 482 ASP A O   1 
ATOM   2013  C CB  . ASP A 1 275 ? -16.215  -40.736 34.668  1.00 58.04  ? 482 ASP A CB  1 
ATOM   2014  C CG  . ASP A 1 275 ? -16.882  -41.052 33.348  1.00 57.30  ? 482 ASP A CG  1 
ATOM   2015  O OD1 . ASP A 1 275 ? -17.924  -40.448 33.064  1.00 64.63  ? 482 ASP A OD1 1 
ATOM   2016  O OD2 . ASP A 1 275 ? -16.350  -41.900 32.623  1.00 60.47  ? 482 ASP A OD2 1 
ATOM   2017  N N   . ASP A 1 276 ? -15.252  -39.817 37.246  1.00 74.18  ? 483 ASP A N   1 
ATOM   2018  C CA  . ASP A 1 276 ? -14.918  -39.664 38.690  1.00 68.26  ? 483 ASP A CA  1 
ATOM   2019  C C   . ASP A 1 276 ? -13.886  -38.573 38.958  1.00 68.94  ? 483 ASP A C   1 
ATOM   2020  O O   . ASP A 1 276 ? -13.693  -38.247 40.135  1.00 71.65  ? 483 ASP A O   1 
ATOM   2021  C CB  . ASP A 1 276 ? -14.423  -40.994 39.257  1.00 60.82  ? 483 ASP A CB  1 
ATOM   2022  C CG  . ASP A 1 276 ? -13.310  -41.651 38.461  1.00 72.46  ? 483 ASP A CG  1 
ATOM   2023  O OD1 . ASP A 1 276 ? -13.551  -42.010 37.296  1.00 74.57  ? 483 ASP A OD1 1 
ATOM   2024  O OD2 . ASP A 1 276 ? -12.218  -41.820 39.024  1.00 77.81  ? 483 ASP A OD2 1 
ATOM   2025  N N   . VAL A 1 277 ? -13.269  -38.007 37.927  1.00 71.26  ? 484 VAL A N   1 
ATOM   2026  C CA  . VAL A 1 277 ? -12.174  -37.059 38.139  1.00 76.33  ? 484 VAL A CA  1 
ATOM   2027  C C   . VAL A 1 277 ? -12.631  -35.669 37.711  1.00 69.76  ? 484 VAL A C   1 
ATOM   2028  O O   . VAL A 1 277 ? -12.974  -35.449 36.541  1.00 68.26  ? 484 VAL A O   1 
ATOM   2029  C CB  . VAL A 1 277 ? -10.893  -37.474 37.386  1.00 69.47  ? 484 VAL A CB  1 
ATOM   2030  C CG1 . VAL A 1 277 ? -9.695   -36.641 37.861  1.00 53.14  ? 484 VAL A CG1 1 
ATOM   2031  C CG2 . VAL A 1 277 ? -10.617  -38.959 37.560  1.00 66.35  ? 484 VAL A CG2 1 
ATOM   2032  N N   . VAL A 1 278 ? -12.602  -34.732 38.653  1.00 64.12  ? 485 VAL A N   1 
ATOM   2033  C CA  . VAL A 1 278 ? -12.935  -33.336 38.411  1.00 68.57  ? 485 VAL A CA  1 
ATOM   2034  C C   . VAL A 1 278 ? -11.671  -32.503 38.599  1.00 70.88  ? 485 VAL A C   1 
ATOM   2035  O O   . VAL A 1 278 ? -11.029  -32.553 39.655  1.00 66.27  ? 485 VAL A O   1 
ATOM   2036  C CB  . VAL A 1 278 ? -14.070  -32.867 39.329  1.00 66.55  ? 485 VAL A CB  1 
ATOM   2037  C CG1 . VAL A 1 278 ? -14.543  -31.465 38.936  1.00 58.05  ? 485 VAL A CG1 1 
ATOM   2038  C CG2 . VAL A 1 278 ? -15.188  -33.877 39.241  1.00 58.34  ? 485 VAL A CG2 1 
ATOM   2039  N N   . SER A 1 279 ? -11.299  -31.763 37.562  1.00 67.35  ? 486 SER A N   1 
ATOM   2040  C CA  . SER A 1 279 ? -10.039  -31.043 37.499  1.00 61.06  ? 486 SER A CA  1 
ATOM   2041  C C   . SER A 1 279 ? -10.344  -29.570 37.373  1.00 62.65  ? 486 SER A C   1 
ATOM   2042  O O   . SER A 1 279 ? -11.375  -29.197 36.828  1.00 68.21  ? 486 SER A O   1 
ATOM   2043  C CB  . SER A 1 279 ? -9.222   -31.477 36.287  1.00 63.14  ? 486 SER A CB  1 
ATOM   2044  O OG  . SER A 1 279 ? -9.425   -32.867 36.055  1.00 76.97  ? 486 SER A OG  1 
ATOM   2045  N N   . ARG A 1 280 ? -9.457   -28.726 37.872  1.00 61.70  ? 487 ARG A N   1 
ATOM   2046  C CA  . ARG A 1 280 ? -9.516   -27.368 37.361  1.00 63.13  ? 487 ARG A CA  1 
ATOM   2047  C C   . ARG A 1 280 ? -8.818   -27.334 35.990  1.00 68.63  ? 487 ARG A C   1 
ATOM   2048  O O   . ARG A 1 280 ? -8.179   -28.306 35.570  1.00 70.87  ? 487 ARG A O   1 
ATOM   2049  C CB  . ARG A 1 280 ? -8.919   -26.383 38.375  1.00 58.11  ? 487 ARG A CB  1 
ATOM   2050  N N   . CYS A 1 281 ? -8.993   -26.237 35.253  1.00 66.13  ? 488 CYS A N   1 
ATOM   2051  C CA  . CYS A 1 281 ? -8.393   -26.107 33.927  1.00 61.71  ? 488 CYS A CA  1 
ATOM   2052  C C   . CYS A 1 281 ? -8.642   -24.689 33.429  1.00 69.20  ? 488 CYS A C   1 
ATOM   2053  O O   . CYS A 1 281 ? -9.383   -23.913 34.042  1.00 66.02  ? 488 CYS A O   1 
ATOM   2054  C CB  . CYS A 1 281 ? -8.946   -27.133 32.932  1.00 66.46  ? 488 CYS A CB  1 
ATOM   2055  S SG  . CYS A 1 281 ? -10.681  -26.852 32.390  1.00 83.08  ? 488 CYS A SG  1 
ATOM   2056  N N   . THR A 1 282 ? -8.008   -24.364 32.305  1.00 68.54  ? 489 THR A N   1 
ATOM   2057  C CA  . THR A 1 282 ? -8.027   -23.029 31.732  1.00 64.72  ? 489 THR A CA  1 
ATOM   2058  C C   . THR A 1 282 ? -9.089   -22.929 30.650  1.00 64.80  ? 489 THR A C   1 
ATOM   2059  O O   . THR A 1 282 ? -9.539   -23.937 30.092  1.00 63.56  ? 489 THR A O   1 
ATOM   2060  C CB  . THR A 1 282 ? -6.670   -22.672 31.127  1.00 64.86  ? 489 THR A CB  1 
ATOM   2061  O OG1 . THR A 1 282 ? -6.203   -23.779 30.344  1.00 65.99  ? 489 THR A OG1 1 
ATOM   2062  C CG2 . THR A 1 282 ? -5.668   -22.325 32.227  1.00 60.97  ? 489 THR A CG2 1 
ATOM   2063  N N   . LYS A 1 283 ? -9.484   -21.681 30.370  1.00 64.46  ? 490 LYS A N   1 
ATOM   2064  C CA  . LYS A 1 283 ? -10.346  -21.384 29.231  1.00 54.69  ? 490 LYS A CA  1 
ATOM   2065  C C   . LYS A 1 283 ? -9.820   -22.051 27.963  1.00 58.03  ? 490 LYS A C   1 
ATOM   2066  O O   . LYS A 1 283 ? -10.553  -22.772 27.276  1.00 52.99  ? 490 LYS A O   1 
ATOM   2067  C CB  . LYS A 1 283 ? -10.450  -19.868 29.054  1.00 46.28  ? 490 LYS A CB  1 
ATOM   2068  C CG  . LYS A 1 283 ? -11.089  -19.128 30.231  1.00 48.49  ? 490 LYS A CG  1 
ATOM   2069  C CD  . LYS A 1 283 ? -11.345  -17.626 29.907  1.00 45.24  ? 490 LYS A CD  1 
ATOM   2070  C CE  . LYS A 1 283 ? -12.089  -16.887 31.032  1.00 44.63  ? 490 LYS A CE  1 
ATOM   2071  N NZ  . LYS A 1 283 ? -13.002  -15.822 30.512  1.00 47.73  ? 490 LYS A NZ  1 
ATOM   2072  N N   . GLU A 1 284 ? -8.540   -21.864 27.671  1.00 65.64  ? 491 GLU A N   1 
ATOM   2073  C CA  . GLU A 1 284 ? -7.943   -22.469 26.458  1.00 64.76  ? 491 GLU A CA  1 
ATOM   2074  C C   . GLU A 1 284 ? -8.236   -23.967 26.424  1.00 62.37  ? 491 GLU A C   1 
ATOM   2075  O O   . GLU A 1 284 ? -8.530   -24.464 25.341  1.00 65.32  ? 491 GLU A O   1 
ATOM   2076  C CB  . GLU A 1 284 ? -6.441   -22.211 26.433  1.00 68.47  ? 491 GLU A CB  1 
ATOM   2077  C CG  . GLU A 1 284 ? -6.019   -21.246 25.346  1.00 82.33  ? 491 GLU A CG  1 
ATOM   2078  C CD  . GLU A 1 284 ? -4.697   -21.583 24.681  1.00 87.93  ? 491 GLU A CD  1 
ATOM   2079  O OE1 . GLU A 1 284 ? -3.834   -22.183 25.348  1.00 91.69  ? 491 GLU A OE1 1 
ATOM   2080  O OE2 . GLU A 1 284 ? -4.534   -21.244 23.496  1.00 78.48  ? 491 GLU A OE2 1 
ATOM   2081  N N   . GLU A 1 285 ? -8.195   -24.644 27.569  1.00 59.80  ? 492 GLU A N   1 
ATOM   2082  C CA  . GLU A 1 285 ? -8.367   -26.087 27.551  1.00 63.51  ? 492 GLU A CA  1 
ATOM   2083  C C   . GLU A 1 285 ? -9.807   -26.525 27.318  1.00 62.68  ? 492 GLU A C   1 
ATOM   2084  O O   . GLU A 1 285 ? -10.028  -27.646 26.836  1.00 60.12  ? 492 GLU A O   1 
ATOM   2085  C CB  . GLU A 1 285 ? -7.874   -26.671 28.860  1.00 67.53  ? 492 GLU A CB  1 
ATOM   2086  C CG  . GLU A 1 285 ? -6.389   -26.557 29.024  1.00 71.03  ? 492 GLU A CG  1 
ATOM   2087  C CD  . GLU A 1 285 ? -5.998   -26.878 30.423  1.00 67.60  ? 492 GLU A CD  1 
ATOM   2088  O OE1 . GLU A 1 285 ? -6.335   -26.056 31.306  1.00 55.34  ? 492 GLU A OE1 1 
ATOM   2089  O OE2 . GLU A 1 285 ? -5.404   -27.965 30.627  1.00 67.69  ? 492 GLU A OE2 1 
ATOM   2090  N N   . ALA A 1 286 ? -10.759  -25.640 27.590  1.00 59.40  ? 493 ALA A N   1 
ATOM   2091  C CA  . ALA A 1 286 ? -12.189  -25.997 27.496  1.00 54.42  ? 493 ALA A CA  1 
ATOM   2092  C C   . ALA A 1 286 ? -12.806  -25.496 26.199  1.00 55.32  ? 493 ALA A C   1 
ATOM   2093  O O   . ALA A 1 286 ? -13.813  -26.062 25.773  1.00 52.53  ? 493 ALA A O   1 
ATOM   2094  C CB  . ALA A 1 286 ? -12.880  -25.358 28.654  1.00 57.25  ? 493 ALA A CB  1 
ATOM   2095  N N   . ILE A 1 287 ? -12.248  -24.438 25.632  1.00 54.39  ? 494 ILE A N   1 
ATOM   2096  C CA  . ILE A 1 287 ? -12.847  -23.835 24.415  1.00 48.23  ? 494 ILE A CA  1 
ATOM   2097  C C   . ILE A 1 287 ? -11.936  -24.130 23.233  1.00 49.76  ? 494 ILE A C   1 
ATOM   2098  O O   . ILE A 1 287 ? -12.286  -25.008 22.450  1.00 53.65  ? 494 ILE A O   1 
ATOM   2099  C CB  . ILE A 1 287 ? -13.080  -22.327 24.627  1.00 50.78  ? 494 ILE A CB  1 
ATOM   2100  C CG1 . ILE A 1 287 ? -13.891  -22.059 25.897  1.00 45.70  ? 494 ILE A CG1 1 
ATOM   2101  C CG2 . ILE A 1 287 ? -13.723  -21.687 23.409  1.00 46.99  ? 494 ILE A CG2 1 
ATOM   2102  C CD1 . ILE A 1 287 ? -13.716  -20.672 26.458  1.00 54.02  ? 494 ILE A CD1 1 
ATOM   2103  N N   . GLU A 1 288 ? -10.775  -23.487 23.157  1.00 47.96  ? 495 GLU A N   1 
ATOM   2104  C CA  . GLU A 1 288 ? -9.963   -23.638 21.948  1.00 53.75  ? 495 GLU A CA  1 
ATOM   2105  C C   . GLU A 1 288 ? -9.516   -25.084 21.715  1.00 57.88  ? 495 GLU A C   1 
ATOM   2106  O O   . GLU A 1 288 ? -9.638   -25.607 20.599  1.00 53.29  ? 495 GLU A O   1 
ATOM   2107  C CB  . GLU A 1 288 ? -8.770   -22.691 22.005  1.00 49.91  ? 495 GLU A CB  1 
ATOM   2108  C CG  . GLU A 1 288 ? -9.166   -21.251 21.727  1.00 47.25  ? 495 GLU A CG  1 
ATOM   2109  C CD  . GLU A 1 288 ? -9.436   -20.482 22.991  1.00 59.28  ? 495 GLU A CD  1 
ATOM   2110  O OE1 . GLU A 1 288 ? -10.127  -21.025 23.885  1.00 62.00  ? 495 GLU A OE1 1 
ATOM   2111  O OE2 . GLU A 1 288 ? -8.960   -19.331 23.098  1.00 67.98  ? 495 GLU A OE2 1 
ATOM   2112  N N   . HIS A 1 289 ? -9.116   -25.768 22.778  1.00 52.49  ? 496 HIS A N   1 
ATOM   2113  C CA  . HIS A 1 289 ? -8.605   -27.152 22.622  1.00 53.70  ? 496 HIS A CA  1 
ATOM   2114  C C   . HIS A 1 289 ? -9.728   -28.090 22.169  1.00 55.71  ? 496 HIS A C   1 
ATOM   2115  O O   . HIS A 1 289 ? -9.420   -29.249 21.857  1.00 49.40  ? 496 HIS A O   1 
ATOM   2116  C CB  . HIS A 1 289 ? -7.931   -27.600 23.919  1.00 57.79  ? 496 HIS A CB  1 
ATOM   2117  C CG  . HIS A 1 289 ? -6.636   -26.926 24.228  1.00 63.02  ? 496 HIS A CG  1 
ATOM   2118  N ND1 . HIS A 1 289 ? -6.277   -25.708 23.691  1.00 66.34  ? 496 HIS A ND1 1 
ATOM   2119  C CD2 . HIS A 1 289 ? -5.619   -27.293 25.034  1.00 66.53  ? 496 HIS A CD2 1 
ATOM   2120  C CE1 . HIS A 1 289 ? -5.096   -25.357 24.149  1.00 66.16  ? 496 HIS A CE1 1 
ATOM   2121  N NE2 . HIS A 1 289 ? -4.671   -26.312 24.973  1.00 67.31  ? 496 HIS A NE2 1 
ATOM   2122  N N   . ASN A 1 290 ? -10.970  -27.602 22.099  1.00 54.12  ? 497 ASN A N   1 
ATOM   2123  C CA  . ASN A 1 290 ? -12.096  -28.442 21.731  1.00 54.93  ? 497 ASN A CA  1 
ATOM   2124  C C   . ASN A 1 290 ? -12.672  -28.082 20.364  1.00 58.37  ? 497 ASN A C   1 
ATOM   2125  O O   . ASN A 1 290 ? -13.694  -28.647 19.957  1.00 56.55  ? 497 ASN A O   1 
ATOM   2126  C CB  . ASN A 1 290 ? -13.153  -28.384 22.831  1.00 54.43  ? 497 ASN A CB  1 
ATOM   2127  C CG  . ASN A 1 290 ? -12.707  -29.113 24.091  1.00 52.08  ? 497 ASN A CG  1 
ATOM   2128  O OD1 . ASN A 1 290 ? -12.206  -30.231 24.017  1.00 51.44  ? 497 ASN A OD1 1 
ATOM   2129  N ND2 . ASN A 1 290 ? -12.892  -28.485 25.250  1.00 50.87  ? 497 ASN A ND2 1 
ATOM   2130  N N   . TYR A 1 291 ? -12.010  -27.190 19.623  1.00 59.67  ? 498 TYR A N   1 
ATOM   2131  C CA  . TYR A 1 291 ? -12.380  -26.962 18.233  1.00 49.74  ? 498 TYR A CA  1 
ATOM   2132  C C   . TYR A 1 291 ? -12.166  -28.200 17.368  1.00 52.82  ? 498 TYR A C   1 
ATOM   2133  O O   . TYR A 1 291 ? -12.766  -28.299 16.293  1.00 57.22  ? 498 TYR A O   1 
ATOM   2134  C CB  . TYR A 1 291 ? -11.579  -25.793 17.667  1.00 49.91  ? 498 TYR A CB  1 
ATOM   2135  C CG  . TYR A 1 291 ? -11.854  -24.465 18.324  1.00 53.16  ? 498 TYR A CG  1 
ATOM   2136  C CD1 . TYR A 1 291 ? -12.874  -24.318 19.267  1.00 51.37  ? 498 TYR A CD1 1 
ATOM   2137  C CD2 . TYR A 1 291 ? -11.115  -23.340 17.973  1.00 49.22  ? 498 TYR A CD2 1 
ATOM   2138  C CE1 . TYR A 1 291 ? -13.130  -23.080 19.850  1.00 53.36  ? 498 TYR A CE1 1 
ATOM   2139  C CE2 . TYR A 1 291 ? -11.367  -22.101 18.541  1.00 45.38  ? 498 TYR A CE2 1 
ATOM   2140  C CZ  . TYR A 1 291 ? -12.363  -21.976 19.482  1.00 52.94  ? 498 TYR A CZ  1 
ATOM   2141  O OH  . TYR A 1 291 ? -12.577  -20.749 20.052  1.00 48.90  ? 498 TYR A OH  1 
ATOM   2142  N N   . GLY A 1 292 ? -11.326  -29.142 17.791  1.00 55.35  ? 499 GLY A N   1 
ATOM   2143  C CA  . GLY A 1 292 ? -11.103  -30.307 16.934  1.00 61.81  ? 499 GLY A CA  1 
ATOM   2144  C C   . GLY A 1 292 ? -10.203  -30.012 15.733  1.00 59.34  ? 499 GLY A C   1 
ATOM   2145  O O   . GLY A 1 292 ? -9.621   -28.938 15.592  1.00 56.24  ? 499 GLY A O   1 
ATOM   2146  N N   . GLY A 1 293 ? -10.099  -31.008 14.856  1.00 65.67  ? 500 GLY A N   1 
ATOM   2147  C CA  . GLY A 1 293 ? -9.238   -30.921 13.677  1.00 64.14  ? 500 GLY A CA  1 
ATOM   2148  C C   . GLY A 1 293 ? -8.225   -32.057 13.541  1.00 75.22  ? 500 GLY A C   1 
ATOM   2149  O O   . GLY A 1 293 ? -7.840   -32.463 12.436  1.00 78.55  ? 500 GLY A O   1 
ATOM   2150  N N   . CYS A 1 303 ? -9.659   -36.739 17.200  1.00 71.53  ? 510 CYS A N   1 
ATOM   2151  C CA  . CYS A 1 303 ? -10.697  -37.606 17.815  1.00 77.47  ? 510 CYS A CA  1 
ATOM   2152  C C   . CYS A 1 303 ? -11.442  -36.854 18.918  1.00 71.82  ? 510 CYS A C   1 
ATOM   2153  O O   . CYS A 1 303 ? -12.576  -37.234 19.188  1.00 73.74  ? 510 CYS A O   1 
ATOM   2154  C CB  . CYS A 1 303 ? -10.070  -38.865 18.403  1.00 73.53  ? 510 CYS A CB  1 
ATOM   2155  S SG  . CYS A 1 303 ? -8.786   -38.544 19.637  1.00 84.06  ? 510 CYS A SG  1 
ATOM   2156  N N   . THR A 1 304 ? -10.853  -35.805 19.486  1.00 63.26  ? 511 THR A N   1 
ATOM   2157  C CA  . THR A 1 304 ? -11.467  -35.118 20.651  1.00 64.05  ? 511 THR A CA  1 
ATOM   2158  C C   . THR A 1 304 ? -11.996  -33.737 20.251  1.00 66.81  ? 511 THR A C   1 
ATOM   2159  O O   . THR A 1 304 ? -11.176  -32.913 19.811  1.00 66.89  ? 511 THR A O   1 
ATOM   2160  C CB  . THR A 1 304 ? -10.435  -35.069 21.782  1.00 65.31  ? 511 THR A CB  1 
ATOM   2161  O OG1 . THR A 1 304 ? -10.127  -36.412 22.151  1.00 70.21  ? 511 THR A OG1 1 
ATOM   2162  C CG2 . THR A 1 304 ? -10.891  -34.296 22.999  1.00 59.88  ? 511 THR A CG2 1 
ATOM   2163  N N   . ASN A 1 305 ? -13.297  -33.483 20.449  1.00 66.42  ? 512 ASN A N   1 
ATOM   2164  C CA  . ASN A 1 305 ? -13.909  -32.225 20.047  1.00 60.88  ? 512 ASN A CA  1 
ATOM   2165  C C   . ASN A 1 305 ? -15.287  -32.088 20.695  1.00 59.39  ? 512 ASN A C   1 
ATOM   2166  O O   . ASN A 1 305 ? -15.910  -33.075 21.102  1.00 56.68  ? 512 ASN A O   1 
ATOM   2167  C CB  . ASN A 1 305 ? -14.010  -32.159 18.521  1.00 53.43  ? 512 ASN A CB  1 
ATOM   2168  C CG  . ASN A 1 305 ? -14.380  -33.504 17.917  1.00 58.68  ? 512 ASN A CG  1 
ATOM   2169  O OD1 . ASN A 1 305 ? -15.438  -34.064 18.217  1.00 57.57  ? 512 ASN A OD1 1 
ATOM   2170  N ND2 . ASN A 1 305 ? -13.497  -34.042 17.087  1.00 62.02  ? 512 ASN A ND2 1 
ATOM   2171  N N   . ALA A 1 306 ? -15.751  -30.843 20.777  1.00 55.20  ? 513 ALA A N   1 
ATOM   2172  C CA  . ALA A 1 306 ? -17.109  -30.569 21.218  1.00 49.61  ? 513 ALA A CA  1 
ATOM   2173  C C   . ALA A 1 306 ? -18.122  -31.199 20.279  1.00 50.46  ? 513 ALA A C   1 
ATOM   2174  O O   . ALA A 1 306 ? -18.016  -31.094 19.052  1.00 55.48  ? 513 ALA A O   1 
ATOM   2175  C CB  . ALA A 1 306 ? -17.350  -29.066 21.288  1.00 51.56  ? 513 ALA A CB  1 
ATOM   2176  N N   . TYR A 1 307 ? -19.102  -31.858 20.867  1.00 48.92  ? 514 TYR A N   1 
ATOM   2177  C CA  . TYR A 1 307 ? -20.277  -32.371 20.181  1.00 50.46  ? 514 TYR A CA  1 
ATOM   2178  C C   . TYR A 1 307 ? -21.524  -31.579 20.527  1.00 48.87  ? 514 TYR A C   1 
ATOM   2179  O O   . TYR A 1 307 ? -22.336  -31.310 19.651  1.00 49.04  ? 514 TYR A O   1 
ATOM   2180  C CB  . TYR A 1 307 ? -20.490  -33.850 20.544  1.00 49.77  ? 514 TYR A CB  1 
ATOM   2181  C CG  . TYR A 1 307 ? -21.728  -34.472 19.960  1.00 45.90  ? 514 TYR A CG  1 
ATOM   2182  C CD1 . TYR A 1 307 ? -22.206  -34.064 18.723  1.00 42.11  ? 514 TYR A CD1 1 
ATOM   2183  C CD2 . TYR A 1 307 ? -22.419  -35.478 20.636  1.00 43.58  ? 514 TYR A CD2 1 
ATOM   2184  C CE1 . TYR A 1 307 ? -23.332  -34.619 18.172  1.00 42.26  ? 514 TYR A CE1 1 
ATOM   2185  C CE2 . TYR A 1 307 ? -23.569  -36.053 20.079  1.00 42.82  ? 514 TYR A CE2 1 
ATOM   2186  C CZ  . TYR A 1 307 ? -24.010  -35.607 18.839  1.00 40.84  ? 514 TYR A CZ  1 
ATOM   2187  O OH  . TYR A 1 307 ? -25.110  -36.125 18.224  1.00 41.00  ? 514 TYR A OH  1 
ATOM   2188  N N   . MET A 1 308 ? -21.650  -31.198 21.795  1.00 49.46  ? 515 MET A N   1 
ATOM   2189  C CA  . MET A 1 308 ? -22.812  -30.411 22.268  1.00 42.70  ? 515 MET A CA  1 
ATOM   2190  C C   . MET A 1 308 ? -22.308  -29.180 23.014  1.00 47.52  ? 515 MET A C   1 
ATOM   2191  O O   . MET A 1 308 ? -21.285  -29.278 23.694  1.00 56.34  ? 515 MET A O   1 
ATOM   2192  C CB  . MET A 1 308 ? -23.668  -31.236 23.225  1.00 45.23  ? 515 MET A CB  1 
ATOM   2193  C CG  . MET A 1 308 ? -25.048  -31.557 22.707  1.00 60.49  ? 515 MET A CG  1 
ATOM   2194  S SD  . MET A 1 308 ? -26.178  -31.931 24.066  1.00 70.88  ? 515 MET A SD  1 
ATOM   2195  C CE  . MET A 1 308 ? -26.217  -30.345 24.897  1.00 49.95  ? 515 MET A CE  1 
ATOM   2196  N N   . LEU A 1 309 ? -23.014  -28.064 22.881  1.00 46.83  ? 516 LEU A N   1 
ATOM   2197  C CA  . LEU A 1 309 ? -22.611  -26.813 23.559  1.00 44.92  ? 516 LEU A CA  1 
ATOM   2198  C C   . LEU A 1 309 ? -23.774  -26.252 24.360  1.00 46.41  ? 516 LEU A C   1 
ATOM   2199  O O   . LEU A 1 309 ? -24.900  -26.306 23.875  1.00 45.75  ? 516 LEU A O   1 
ATOM   2200  C CB  . LEU A 1 309 ? -22.180  -25.792 22.507  1.00 40.46  ? 516 LEU A CB  1 
ATOM   2201  C CG  . LEU A 1 309 ? -20.832  -26.029 21.841  1.00 53.46  ? 516 LEU A CG  1 
ATOM   2202  C CD1 . LEU A 1 309 ? -20.677  -25.103 20.652  1.00 50.17  ? 516 LEU A CD1 1 
ATOM   2203  C CD2 . LEU A 1 309 ? -19.707  -25.818 22.835  1.00 51.08  ? 516 LEU A CD2 1 
ATOM   2204  N N   . VAL A 1 310 ? -23.488  -25.753 25.555  1.00 45.60  ? 517 VAL A N   1 
ATOM   2205  C CA  . VAL A 1 310 ? -24.541  -25.110 26.383  1.00 41.45  ? 517 VAL A CA  1 
ATOM   2206  C C   . VAL A 1 310 ? -24.185  -23.637 26.561  1.00 43.72  ? 517 VAL A C   1 
ATOM   2207  O O   . VAL A 1 310 ? -23.120  -23.352 27.090  1.00 42.35  ? 517 VAL A O   1 
ATOM   2208  C CB  . VAL A 1 310 ? -24.752  -25.837 27.720  1.00 36.14  ? 517 VAL A CB  1 
ATOM   2209  C CG1 . VAL A 1 310 ? -25.754  -25.124 28.608  1.00 33.42  ? 517 VAL A CG1 1 
ATOM   2210  C CG2 . VAL A 1 310 ? -25.154  -27.283 27.505  1.00 35.36  ? 517 VAL A CG2 1 
ATOM   2211  N N   . TYR A 1 311 ? -25.014  -22.756 26.021  1.00 40.17  ? 518 TYR A N   1 
ATOM   2212  C CA  . TYR A 1 311 ? -24.862  -21.304 26.209  1.00 43.23  ? 518 TYR A CA  1 
ATOM   2213  C C   . TYR A 1 311 ? -26.067  -20.847 27.020  1.00 46.92  ? 518 TYR A C   1 
ATOM   2214  O O   . TYR A 1 311 ? -27.150  -21.338 26.795  1.00 51.87  ? 518 TYR A O   1 
ATOM   2215  C CB  . TYR A 1 311 ? -24.839  -20.565 24.875  1.00 50.37  ? 518 TYR A CB  1 
ATOM   2216  C CG  . TYR A 1 311 ? -23.574  -20.677 24.074  1.00 42.05  ? 518 TYR A CG  1 
ATOM   2217  C CD1 . TYR A 1 311 ? -23.301  -21.817 23.345  1.00 38.49  ? 518 TYR A CD1 1 
ATOM   2218  C CD2 . TYR A 1 311 ? -22.671  -19.633 24.018  1.00 47.72  ? 518 TYR A CD2 1 
ATOM   2219  C CE1 . TYR A 1 311 ? -22.149  -21.928 22.594  1.00 45.76  ? 518 TYR A CE1 1 
ATOM   2220  C CE2 . TYR A 1 311 ? -21.510  -19.728 23.273  1.00 49.03  ? 518 TYR A CE2 1 
ATOM   2221  C CZ  . TYR A 1 311 ? -21.252  -20.882 22.559  1.00 46.38  ? 518 TYR A CZ  1 
ATOM   2222  O OH  . TYR A 1 311 ? -20.119  -21.014 21.822  1.00 53.05  ? 518 TYR A OH  1 
ATOM   2223  N N   . ILE A 1 312 ? -25.866  -19.959 27.971  1.00 48.30  ? 519 ILE A N   1 
ATOM   2224  C CA  . ILE A 1 312 ? -26.917  -19.396 28.801  1.00 52.99  ? 519 ILE A CA  1 
ATOM   2225  C C   . ILE A 1 312 ? -27.097  -17.929 28.435  1.00 54.31  ? 519 ILE A C   1 
ATOM   2226  O O   . ILE A 1 312 ? -26.117  -17.206 28.211  1.00 58.73  ? 519 ILE A O   1 
ATOM   2227  C CB  . ILE A 1 312 ? -26.567  -19.580 30.286  1.00 49.14  ? 519 ILE A CB  1 
ATOM   2228  C CG1 . ILE A 1 312 ? -26.369  -21.067 30.548  1.00 47.10  ? 519 ILE A CG1 1 
ATOM   2229  C CG2 . ILE A 1 312 ? -27.658  -19.045 31.150  1.00 51.74  ? 519 ILE A CG2 1 
ATOM   2230  C CD1 . ILE A 1 312 ? -26.065  -21.417 31.954  1.00 45.55  ? 519 ILE A CD1 1 
ATOM   2231  N N   . ARG A 1 313 ? -28.349  -17.497 28.338  1.00 52.56  ? 520 ARG A N   1 
ATOM   2232  C CA  . ARG A 1 313 ? -28.610  -16.121 27.937  1.00 60.23  ? 520 ARG A CA  1 
ATOM   2233  C C   . ARG A 1 313 ? -28.101  -15.172 29.014  1.00 61.98  ? 520 ARG A C   1 
ATOM   2234  O O   . ARG A 1 313 ? -28.409  -15.343 30.202  1.00 57.72  ? 520 ARG A O   1 
ATOM   2235  C CB  . ARG A 1 313 ? -30.103  -15.899 27.693  1.00 53.54  ? 520 ARG A CB  1 
ATOM   2236  C CG  . ARG A 1 313 ? -30.370  -14.585 27.032  1.00 55.63  ? 520 ARG A CG  1 
ATOM   2237  C CD  . ARG A 1 313 ? -31.848  -14.244 27.016  1.00 60.44  ? 520 ARG A CD  1 
ATOM   2238  N NE  . ARG A 1 313 ? -32.122  -13.234 25.999  1.00 59.11  ? 520 ARG A NE  1 
ATOM   2239  C CZ  . ARG A 1 313 ? -32.774  -13.465 24.869  1.00 54.36  ? 520 ARG A CZ  1 
ATOM   2240  N NH1 . ARG A 1 313 ? -33.246  -14.667 24.593  1.00 52.32  ? 520 ARG A NH1 1 
ATOM   2241  N NH2 . ARG A 1 313 ? -32.951  -12.483 24.013  1.00 62.26  ? 520 ARG A NH2 1 
ATOM   2242  N N   . GLU A 1 314 ? -27.294  -14.187 28.599  1.00 57.21  ? 521 GLU A N   1 
ATOM   2243  C CA  . GLU A 1 314 ? -26.649  -13.310 29.571  1.00 56.44  ? 521 GLU A CA  1 
ATOM   2244  C C   . GLU A 1 314 ? -27.679  -12.661 30.494  1.00 63.26  ? 521 GLU A C   1 
ATOM   2245  O O   . GLU A 1 314 ? -27.511  -12.658 31.723  1.00 61.39  ? 521 GLU A O   1 
ATOM   2246  C CB  . GLU A 1 314 ? -25.806  -12.254 28.857  1.00 61.12  ? 521 GLU A CB  1 
ATOM   2247  N N   . SER A 1 315 ? -28.782  -12.157 29.933  1.00 62.47  ? 522 SER A N   1 
ATOM   2248  C CA  . SER A 1 315 ? -29.775  -11.519 30.787  1.00 54.52  ? 522 SER A CA  1 
ATOM   2249  C C   . SER A 1 315 ? -30.299  -12.465 31.863  1.00 53.49  ? 522 SER A C   1 
ATOM   2250  O O   . SER A 1 315 ? -30.699  -12.010 32.933  1.00 60.05  ? 522 SER A O   1 
ATOM   2251  C CB  . SER A 1 315 ? -30.917  -10.966 29.938  1.00 50.32  ? 522 SER A CB  1 
ATOM   2252  O OG  . SER A 1 315 ? -31.722  -11.999 29.411  1.00 55.97  ? 522 SER A OG  1 
ATOM   2253  N N   . LYS A 1 316 ? -30.266  -13.774 31.639  1.00 54.90  ? 523 LYS A N   1 
ATOM   2254  C CA  . LYS A 1 316 ? -30.928  -14.700 32.599  1.00 55.53  ? 523 LYS A CA  1 
ATOM   2255  C C   . LYS A 1 316 ? -29.943  -15.510 33.446  1.00 54.92  ? 523 LYS A C   1 
ATOM   2256  O O   . LYS A 1 316 ? -30.419  -16.328 34.230  1.00 56.76  ? 523 LYS A O   1 
ATOM   2257  C CB  . LYS A 1 316 ? -31.833  -15.652 31.816  1.00 56.56  ? 523 LYS A CB  1 
ATOM   2258  C CG  . LYS A 1 316 ? -32.944  -14.997 31.012  1.00 58.71  ? 523 LYS A CG  1 
ATOM   2259  C CD  . LYS A 1 316 ? -34.001  -14.372 31.888  1.00 63.47  ? 523 LYS A CD  1 
ATOM   2260  C CE  . LYS A 1 316 ? -35.069  -13.650 31.098  1.00 62.44  ? 523 LYS A CE  1 
ATOM   2261  N NZ  . LYS A 1 316 ? -36.385  -14.317 31.231  1.00 69.47  ? 523 LYS A NZ  1 
ATOM   2262  N N   . LEU A 1 317 ? -28.642  -15.266 33.344  1.00 56.86  ? 524 LEU A N   1 
ATOM   2263  C CA  . LEU A 1 317 ? -27.626  -16.076 34.068  1.00 53.67  ? 524 LEU A CA  1 
ATOM   2264  C C   . LEU A 1 317 ? -27.861  -16.035 35.578  1.00 55.84  ? 524 LEU A C   1 
ATOM   2265  O O   . LEU A 1 317 ? -27.724  -17.071 36.210  1.00 57.46  ? 524 LEU A O   1 
ATOM   2266  C CB  . LEU A 1 317 ? -26.246  -15.518 33.721  1.00 52.06  ? 524 LEU A CB  1 
ATOM   2267  C CG  . LEU A 1 317 ? -25.062  -16.458 33.928  1.00 57.35  ? 524 LEU A CG  1 
ATOM   2268  C CD1 . LEU A 1 317 ? -24.327  -16.692 32.620  1.00 49.70  ? 524 LEU A CD1 1 
ATOM   2269  C CD2 . LEU A 1 317 ? -24.113  -15.901 34.975  1.00 62.75  ? 524 LEU A CD2 1 
ATOM   2270  N N   . SER A 1 318 ? -28.188  -14.873 36.130  1.00 56.06  ? 525 SER A N   1 
ATOM   2271  C CA  . SER A 1 318 ? -28.380  -14.723 37.592  1.00 55.82  ? 525 SER A CA  1 
ATOM   2272  C C   . SER A 1 318 ? -29.441  -15.688 38.108  1.00 57.99  ? 525 SER A C   1 
ATOM   2273  O O   . SER A 1 318 ? -29.245  -16.222 39.194  1.00 57.78  ? 525 SER A O   1 
ATOM   2274  C CB  . SER A 1 318 ? -28.755  -13.307 37.899  1.00 53.49  ? 525 SER A CB  1 
ATOM   2275  O OG  . SER A 1 318 ? -29.901  -12.913 37.159  1.00 60.37  ? 525 SER A OG  1 
ATOM   2276  N N   . GLU A 1 319 ? -30.534  -15.862 37.368  1.00 59.38  ? 526 GLU A N   1 
ATOM   2277  C CA  . GLU A 1 319 ? -31.643  -16.754 37.775  1.00 56.48  ? 526 GLU A CA  1 
ATOM   2278  C C   . GLU A 1 319 ? -31.256  -18.199 37.501  1.00 54.26  ? 526 GLU A C   1 
ATOM   2279  O O   . GLU A 1 319 ? -31.362  -19.014 38.420  1.00 59.62  ? 526 GLU A O   1 
ATOM   2280  C CB  . GLU A 1 319 ? -32.875  -16.394 36.955  1.00 52.48  ? 526 GLU A CB  1 
ATOM   2281  C CG  . GLU A 1 319 ? -34.196  -16.758 37.597  1.00 56.37  ? 526 GLU A CG  1 
ATOM   2282  C CD  . GLU A 1 319 ? -35.380  -16.395 36.721  1.00 59.77  ? 526 GLU A CD  1 
ATOM   2283  O OE1 . GLU A 1 319 ? -36.235  -17.265 36.496  1.00 64.28  ? 526 GLU A OE1 1 
ATOM   2284  O OE2 . GLU A 1 319 ? -35.435  -15.243 36.257  1.00 56.70  ? 526 GLU A OE2 1 
ATOM   2285  N N   . VAL A 1 320 ? -30.838  -18.494 36.276  1.00 51.94  ? 527 VAL A N   1 
ATOM   2286  C CA  . VAL A 1 320 ? -30.499  -19.890 35.897  1.00 50.43  ? 527 VAL A CA  1 
ATOM   2287  C C   . VAL A 1 320 ? -29.417  -20.393 36.842  1.00 52.83  ? 527 VAL A C   1 
ATOM   2288  O O   . VAL A 1 320 ? -29.590  -21.478 37.389  1.00 48.04  ? 527 VAL A O   1 
ATOM   2289  C CB  . VAL A 1 320 ? -30.063  -19.967 34.424  1.00 49.83  ? 527 VAL A CB  1 
ATOM   2290  C CG1 . VAL A 1 320 ? -29.540  -21.344 34.053  1.00 46.67  ? 527 VAL A CG1 1 
ATOM   2291  C CG2 . VAL A 1 320 ? -31.191  -19.567 33.490  1.00 49.45  ? 527 VAL A CG2 1 
ATOM   2292  N N   . LEU A 1 321 ? -28.361  -19.610 37.033  1.00 57.30  ? 528 LEU A N   1 
ATOM   2293  C CA  . LEU A 1 321 ? -27.216  -20.060 37.860  1.00 55.80  ? 528 LEU A CA  1 
ATOM   2294  C C   . LEU A 1 321 ? -27.285  -19.422 39.247  1.00 61.41  ? 528 LEU A C   1 
ATOM   2295  O O   . LEU A 1 321 ? -26.218  -19.164 39.824  1.00 54.29  ? 528 LEU A O   1 
ATOM   2296  C CB  . LEU A 1 321 ? -25.925  -19.715 37.120  1.00 50.74  ? 528 LEU A CB  1 
ATOM   2297  C CG  . LEU A 1 321 ? -25.801  -20.307 35.721  1.00 52.37  ? 528 LEU A CG  1 
ATOM   2298  C CD1 . LEU A 1 321 ? -24.486  -19.901 35.089  1.00 57.34  ? 528 LEU A CD1 1 
ATOM   2299  C CD2 . LEU A 1 321 ? -25.922  -21.817 35.771  1.00 43.50  ? 528 LEU A CD2 1 
ATOM   2300  N N   . GLN A 1 322 ? -28.496  -19.192 39.769  1.00 59.70  ? 529 GLN A N   1 
ATOM   2301  C CA  . GLN A 1 322 ? -28.620  -18.726 41.160  1.00 51.09  ? 529 GLN A CA  1 
ATOM   2302  C C   . GLN A 1 322 ? -28.049  -19.825 42.034  1.00 56.53  ? 529 GLN A C   1 
ATOM   2303  O O   . GLN A 1 322 ? -28.177  -21.006 41.688  1.00 49.45  ? 529 GLN A O   1 
ATOM   2304  C CB  . GLN A 1 322 ? -30.077  -18.481 41.529  1.00 55.94  ? 529 GLN A CB  1 
ATOM   2305  N N   . ALA A 1 323 ? -27.517  -19.444 43.178  1.00 64.38  ? 530 ALA A N   1 
ATOM   2306  C CA  . ALA A 1 323 ? -26.809  -20.408 44.005  1.00 59.67  ? 530 ALA A CA  1 
ATOM   2307  C C   . ALA A 1 323 ? -27.811  -21.210 44.819  1.00 61.23  ? 530 ALA A C   1 
ATOM   2308  O O   . ALA A 1 323 ? -28.884  -20.716 45.175  1.00 62.99  ? 530 ALA A O   1 
ATOM   2309  C CB  . ALA A 1 323 ? -25.797  -19.703 44.903  1.00 54.92  ? 530 ALA A CB  1 
ATOM   2310  N N   . VAL A 1 324 ? -27.465  -22.470 45.079  1.00 59.15  ? 531 VAL A N   1 
ATOM   2311  C CA  . VAL A 1 324 ? -28.394  -23.455 45.627  1.00 68.69  ? 531 VAL A CA  1 
ATOM   2312  C C   . VAL A 1 324 ? -27.857  -23.955 46.958  1.00 76.88  ? 531 VAL A C   1 
ATOM   2313  O O   . VAL A 1 324 ? -26.692  -24.365 47.041  1.00 76.99  ? 531 VAL A O   1 
ATOM   2314  C CB  . VAL A 1 324 ? -28.586  -24.641 44.667  1.00 72.34  ? 531 VAL A CB  1 
ATOM   2315  C CG1 . VAL A 1 324 ? -29.872  -25.412 45.031  1.00 69.14  ? 531 VAL A CG1 1 
ATOM   2316  C CG2 . VAL A 1 324 ? -28.541  -24.173 43.192  1.00 58.55  ? 531 VAL A CG2 1 
ATOM   2317  N N   . THR A 1 325 ? -28.713  -23.966 47.982  1.00 74.60  ? 532 THR A N   1 
ATOM   2318  C CA  . THR A 1 325 ? -28.302  -24.340 49.335  1.00 75.01  ? 532 THR A CA  1 
ATOM   2319  C C   . THR A 1 325 ? -29.170  -25.476 49.874  1.00 80.62  ? 532 THR A C   1 
ATOM   2320  O O   . THR A 1 325 ? -30.101  -25.956 49.217  1.00 81.13  ? 532 THR A O   1 
ATOM   2321  C CB  . THR A 1 325 ? -28.375  -23.145 50.284  1.00 73.04  ? 532 THR A CB  1 
ATOM   2322  O OG1 . THR A 1 325 ? -29.694  -22.593 50.245  1.00 72.86  ? 532 THR A OG1 1 
ATOM   2323  C CG2 . THR A 1 325 ? -27.355  -22.085 49.886  1.00 74.45  ? 532 THR A CG2 1 
ATOM   2324  N N   . ASP A 1 326 ? -28.900  -25.867 51.112  1.00 74.92  ? 533 ASP A N   1 
ATOM   2325  C CA  . ASP A 1 326 ? -29.749  -26.908 51.736  1.00 71.34  ? 533 ASP A CA  1 
ATOM   2326  C C   . ASP A 1 326 ? -31.131  -26.305 51.981  1.00 75.33  ? 533 ASP A C   1 
ATOM   2327  O O   . ASP A 1 326 ? -32.055  -27.079 52.259  1.00 77.90  ? 533 ASP A O   1 
ATOM   2328  C CB  . ASP A 1 326 ? -29.074  -27.480 52.980  1.00 71.03  ? 533 ASP A CB  1 
ATOM   2329  C CG  . ASP A 1 326 ? -27.854  -28.330 52.683  1.00 80.74  ? 533 ASP A CG  1 
ATOM   2330  O OD1 . ASP A 1 326 ? -27.278  -28.176 51.591  1.00 79.48  ? 533 ASP A OD1 1 
ATOM   2331  O OD2 . ASP A 1 326 ? -27.487  -29.136 53.554  1.00 89.08  ? 533 ASP A OD2 1 
ATOM   2332  N N   . HIS A 1 327 ? -31.264  -24.978 51.896  1.00 71.77  ? 534 HIS A N   1 
ATOM   2333  C CA  . HIS A 1 327 ? -32.576  -24.360 52.007  1.00 75.09  ? 534 HIS A CA  1 
ATOM   2334  C C   . HIS A 1 327 ? -33.453  -24.589 50.777  1.00 74.78  ? 534 HIS A C   1 
ATOM   2335  O O   . HIS A 1 327 ? -34.634  -24.227 50.804  1.00 70.43  ? 534 HIS A O   1 
ATOM   2336  C CB  . HIS A 1 327 ? -32.426  -22.856 52.238  1.00 80.48  ? 534 HIS A CB  1 
ATOM   2337  C CG  . HIS A 1 327 ? -31.855  -22.498 53.576  1.00 91.81  ? 534 HIS A CG  1 
ATOM   2338  N ND1 . HIS A 1 327 ? -32.148  -23.204 54.723  1.00 97.45  ? 534 HIS A ND1 1 
ATOM   2339  C CD2 . HIS A 1 327 ? -31.018  -21.502 53.951  1.00 110.71 ? 534 HIS A CD2 1 
ATOM   2340  C CE1 . HIS A 1 327 ? -31.510  -22.663 55.746  1.00 117.14 ? 534 HIS A CE1 1 
ATOM   2341  N NE2 . HIS A 1 327 ? -30.819  -21.628 55.304  1.00 128.04 ? 534 HIS A NE2 1 
ATOM   2342  N N   . ASP A 1 328 ? -32.905  -25.148 49.699  1.00 74.82  ? 535 ASP A N   1 
ATOM   2343  C CA  . ASP A 1 328 ? -33.656  -25.410 48.485  1.00 64.25  ? 535 ASP A CA  1 
ATOM   2344  C C   . ASP A 1 328 ? -34.048  -26.870 48.352  1.00 68.28  ? 535 ASP A C   1 
ATOM   2345  O O   . ASP A 1 328 ? -34.746  -27.220 47.401  1.00 69.56  ? 535 ASP A O   1 
ATOM   2346  C CB  . ASP A 1 328 ? -32.848  -24.997 47.256  1.00 62.36  ? 535 ASP A CB  1 
ATOM   2347  C CG  . ASP A 1 328 ? -32.414  -23.547 47.289  1.00 70.25  ? 535 ASP A CG  1 
ATOM   2348  O OD1 . ASP A 1 328 ? -33.285  -22.641 47.342  1.00 62.46  ? 535 ASP A OD1 1 
ATOM   2349  O OD2 . ASP A 1 328 ? -31.177  -23.326 47.235  1.00 70.93  ? 535 ASP A OD2 1 
ATOM   2350  N N   . ILE A 1 329 ? -33.567  -27.724 49.246  1.00 67.99  ? 536 ILE A N   1 
ATOM   2351  C CA  . ILE A 1 329 ? -33.918  -29.170 49.204  1.00 61.48  ? 536 ILE A CA  1 
ATOM   2352  C C   . ILE A 1 329 ? -35.007  -29.420 50.246  1.00 72.49  ? 536 ILE A C   1 
ATOM   2353  O O   . ILE A 1 329 ? -34.677  -29.395 51.442  1.00 72.00  ? 536 ILE A O   1 
ATOM   2354  C CB  . ILE A 1 329 ? -32.668  -30.031 49.447  1.00 59.93  ? 536 ILE A CB  1 
ATOM   2355  C CG1 . ILE A 1 329 ? -31.434  -29.406 48.794  1.00 68.22  ? 536 ILE A CG1 1 
ATOM   2356  C CG2 . ILE A 1 329 ? -32.900  -31.457 48.983  1.00 65.41  ? 536 ILE A CG2 1 
ATOM   2357  C CD1 . ILE A 1 329 ? -30.223  -30.288 48.793  1.00 60.46  ? 536 ILE A CD1 1 
ATOM   2358  N N   . PRO A 1 330 ? -36.291  -29.612 49.861  1.00 74.24  ? 537 PRO A N   1 
ATOM   2359  C CA  . PRO A 1 330 ? -37.355  -29.920 50.826  1.00 74.89  ? 537 PRO A CA  1 
ATOM   2360  C C   . PRO A 1 330 ? -36.969  -30.975 51.861  1.00 75.93  ? 537 PRO A C   1 
ATOM   2361  O O   . PRO A 1 330 ? -36.259  -31.939 51.571  1.00 74.96  ? 537 PRO A O   1 
ATOM   2362  C CB  . PRO A 1 330 ? -38.490  -30.404 49.925  1.00 67.65  ? 537 PRO A CB  1 
ATOM   2363  C CG  . PRO A 1 330 ? -38.338  -29.568 48.715  1.00 63.82  ? 537 PRO A CG  1 
ATOM   2364  C CD  . PRO A 1 330 ? -36.846  -29.375 48.515  1.00 73.68  ? 537 PRO A CD  1 
ATOM   2365  N N   . GLN A 1 331 ? -37.464  -30.774 53.085  1.00 76.55  ? 538 GLN A N   1 
ATOM   2366  C CA  . GLN A 1 331 ? -37.086  -31.629 54.203  1.00 78.34  ? 538 GLN A CA  1 
ATOM   2367  C C   . GLN A 1 331 ? -37.615  -33.048 54.025  1.00 79.11  ? 538 GLN A C   1 
ATOM   2368  O O   . GLN A 1 331 ? -36.918  -34.024 54.339  1.00 78.97  ? 538 GLN A O   1 
ATOM   2369  C CB  . GLN A 1 331 ? -37.593  -31.018 55.514  1.00 76.30  ? 538 GLN A CB  1 
ATOM   2370  N N   . GLN A 1 332 ? -38.848  -33.182 53.529  1.00 77.34  ? 539 GLN A N   1 
ATOM   2371  C CA  . GLN A 1 332 ? -39.399  -34.507 53.288  1.00 79.56  ? 539 GLN A CA  1 
ATOM   2372  C C   . GLN A 1 332 ? -38.465  -35.331 52.408  1.00 84.62  ? 539 GLN A C   1 
ATOM   2373  O O   . GLN A 1 332 ? -38.305  -36.541 52.619  1.00 84.47  ? 539 GLN A O   1 
ATOM   2374  C CB  . GLN A 1 332 ? -40.789  -34.378 52.662  1.00 76.08  ? 539 GLN A CB  1 
ATOM   2375  N N   . LEU A 1 333 ? -37.801  -34.675 51.458  1.00 85.43  ? 540 LEU A N   1 
ATOM   2376  C CA  . LEU A 1 333 ? -36.859  -35.385 50.553  1.00 83.39  ? 540 LEU A CA  1 
ATOM   2377  C C   . LEU A 1 333 ? -35.650  -35.861 51.363  1.00 81.04  ? 540 LEU A C   1 
ATOM   2378  O O   . LEU A 1 333 ? -35.317  -37.036 51.256  1.00 82.10  ? 540 LEU A O   1 
ATOM   2379  C CB  . LEU A 1 333 ? -36.455  -34.448 49.410  1.00 75.97  ? 540 LEU A CB  1 
ATOM   2380  C CG  . LEU A 1 333 ? -35.391  -34.962 48.443  1.00 70.58  ? 540 LEU A CG  1 
ATOM   2381  C CD1 . LEU A 1 333 ? -35.790  -36.302 47.848  1.00 70.67  ? 540 LEU A CD1 1 
ATOM   2382  C CD2 . LEU A 1 333 ? -35.151  -33.949 47.338  1.00 68.48  ? 540 LEU A CD2 1 
ATOM   2383  N N   . VAL A 1 334 ? -35.026  -34.977 52.141  1.00 80.64  ? 541 VAL A N   1 
ATOM   2384  C CA  . VAL A 1 334 ? -33.810  -35.364 52.909  1.00 85.74  ? 541 VAL A CA  1 
ATOM   2385  C C   . VAL A 1 334 ? -34.140  -36.580 53.778  1.00 85.69  ? 541 VAL A C   1 
ATOM   2386  O O   . VAL A 1 334 ? -33.333  -37.503 53.791  1.00 83.66  ? 541 VAL A O   1 
ATOM   2387  C CB  . VAL A 1 334 ? -33.268  -34.182 53.732  1.00 81.05  ? 541 VAL A CB  1 
ATOM   2388  C CG1 . VAL A 1 334 ? -31.935  -34.505 54.385  1.00 79.46  ? 541 VAL A CG1 1 
ATOM   2389  C CG2 . VAL A 1 334 ? -33.154  -32.922 52.891  1.00 70.90  ? 541 VAL A CG2 1 
ATOM   2390  N N   . GLU A 1 335 ? -35.299  -36.586 54.441  1.00 85.79  ? 542 GLU A N   1 
ATOM   2391  C CA  . GLU A 1 335 ? -35.679  -37.708 55.292  1.00 91.23  ? 542 GLU A CA  1 
ATOM   2392  C C   . GLU A 1 335 ? -35.862  -38.975 54.467  1.00 87.58  ? 542 GLU A C   1 
ATOM   2393  O O   . GLU A 1 335 ? -35.403  -40.054 54.863  1.00 88.77  ? 542 GLU A O   1 
ATOM   2394  C CB  . GLU A 1 335 ? -36.949  -37.372 56.080  1.00 84.33  ? 542 GLU A CB  1 
ATOM   2395  N N   . ARG A 1 336 ? -36.516  -38.860 53.307  1.00 79.13  ? 543 ARG A N   1 
ATOM   2396  C CA  . ARG A 1 336 ? -36.612  -40.001 52.406  1.00 84.96  ? 543 ARG A CA  1 
ATOM   2397  C C   . ARG A 1 336 ? -35.223  -40.487 51.994  1.00 89.81  ? 543 ARG A C   1 
ATOM   2398  O O   . ARG A 1 336 ? -34.911  -41.681 52.097  1.00 85.10  ? 543 ARG A O   1 
ATOM   2399  C CB  . ARG A 1 336 ? -37.451  -39.631 51.182  1.00 81.79  ? 543 ARG A CB  1 
ATOM   2400  N N   . LEU A 1 337 ? -34.363  -39.565 51.549  1.00 87.60  ? 544 LEU A N   1 
ATOM   2401  C CA  . LEU A 1 337 ? -33.044  -39.957 51.068  1.00 82.55  ? 544 LEU A CA  1 
ATOM   2402  C C   . LEU A 1 337 ? -32.192  -40.541 52.195  1.00 93.05  ? 544 LEU A C   1 
ATOM   2403  O O   . LEU A 1 337 ? -31.595  -41.616 52.036  1.00 93.52  ? 544 LEU A O   1 
ATOM   2404  C CB  . LEU A 1 337 ? -32.352  -38.762 50.411  1.00 78.06  ? 544 LEU A CB  1 
ATOM   2405  N N   . GLN A 1 338 ? -32.133  -39.856 53.347  1.00 93.86  ? 545 GLN A N   1 
ATOM   2406  C CA  . GLN A 1 338 ? -31.288  -40.313 54.452  1.00 93.70  ? 545 GLN A CA  1 
ATOM   2407  C C   . GLN A 1 338 ? -31.666  -41.728 54.882  1.00 94.97  ? 545 GLN A C   1 
ATOM   2408  O O   . GLN A 1 338 ? -30.848  -42.658 54.810  1.00 91.37  ? 545 GLN A O   1 
ATOM   2409  C CB  . GLN A 1 338 ? -31.380  -39.334 55.628  1.00 92.40  ? 545 GLN A CB  1 
ATOM   2410  N N   . GLU A 1 339 ? -32.949  -41.877 55.244  1.00 98.94  ? 546 GLU A N   1 
ATOM   2411  C CA  . GLU A 1 339 ? -33.494  -43.197 55.657  1.00 102.48 ? 546 GLU A CA  1 
ATOM   2412  C C   . GLU A 1 339 ? -33.697  -44.032 54.403  1.00 97.07  ? 546 GLU A C   1 
ATOM   2413  O O   . GLU A 1 339 ? -34.854  -44.198 53.980  1.00 96.75  ? 546 GLU A O   1 
ATOM   2414  C CB  . GLU A 1 339 ? -34.807  -43.020 56.416  1.00 100.02 ? 546 GLU A CB  1 
ATOM   2415  N N   . GLU A 1 340 ? -32.605  -44.542 53.856  1.00 101.40 ? 547 GLU A N   1 
ATOM   2416  C CA  . GLU A 1 340 ? -32.635  -45.326 52.626  1.00 98.55  ? 547 GLU A CA  1 
ATOM   2417  C C   . GLU A 1 340 ? -31.326  -46.099 52.485  1.00 92.98  ? 547 GLU A C   1 
ATOM   2418  O O   . GLU A 1 340 ? -30.293  -45.699 53.031  1.00 94.55  ? 547 GLU A O   1 
ATOM   2419  C CB  . GLU A 1 340 ? -32.864  -44.431 51.403  1.00 87.23  ? 547 GLU A CB  1 
ATOM   2420  N N   . MET B 2 1   ? -49.346  -36.311 2.590   1.00 50.87  ? 1   MET B N   1 
ATOM   2421  C CA  . MET B 2 1   ? -48.978  -34.919 2.826   1.00 55.50  ? 1   MET B CA  1 
ATOM   2422  C C   . MET B 2 1   ? -47.496  -34.710 2.610   1.00 51.72  ? 1   MET B C   1 
ATOM   2423  O O   . MET B 2 1   ? -46.701  -35.651 2.681   1.00 52.96  ? 1   MET B O   1 
ATOM   2424  C CB  . MET B 2 1   ? -49.364  -34.469 4.253   1.00 57.06  ? 1   MET B CB  1 
ATOM   2425  C CG  . MET B 2 1   ? -48.955  -35.432 5.374   1.00 54.49  ? 1   MET B CG  1 
ATOM   2426  S SD  . MET B 2 1   ? -49.387  -34.928 7.064   1.00 49.93  ? 1   MET B SD  1 
ATOM   2427  C CE  . MET B 2 1   ? -48.500  -36.168 8.000   1.00 47.55  ? 1   MET B CE  1 
ATOM   2428  N N   . GLN B 2 2   ? -47.135  -33.455 2.372   1.00 50.58  ? 2   GLN B N   1 
ATOM   2429  C CA  . GLN B 2 2   ? -45.712  -33.119 2.184   1.00 44.49  ? 2   GLN B CA  1 
ATOM   2430  C C   . GLN B 2 2   ? -45.163  -32.521 3.468   1.00 49.14  ? 2   GLN B C   1 
ATOM   2431  O O   . GLN B 2 2   ? -45.581  -31.411 3.821   1.00 53.03  ? 2   GLN B O   1 
ATOM   2432  C CB  . GLN B 2 2   ? -45.534  -32.106 1.062   1.00 46.72  ? 2   GLN B CB  1 
ATOM   2433  C CG  . GLN B 2 2   ? -44.081  -31.858 0.708   1.00 47.46  ? 2   GLN B CG  1 
ATOM   2434  C CD  . GLN B 2 2   ? -43.943  -30.753 -0.304  1.00 47.95  ? 2   GLN B CD  1 
ATOM   2435  O OE1 . GLN B 2 2   ? -43.863  -29.580 0.040   1.00 56.07  ? 2   GLN B OE1 1 
ATOM   2436  N NE2 . GLN B 2 2   ? -43.915  -31.126 -1.570  1.00 46.63  ? 2   GLN B NE2 1 
ATOM   2437  N N   . ILE B 2 3   ? -44.287  -33.252 4.147   1.00 42.32  ? 3   ILE B N   1 
ATOM   2438  C CA  . ILE B 2 3   ? -43.594  -32.669 5.324   1.00 40.97  ? 3   ILE B CA  1 
ATOM   2439  C C   . ILE B 2 3   ? -42.180  -32.300 4.884   1.00 43.08  ? 3   ILE B C   1 
ATOM   2440  O O   . ILE B 2 3   ? -41.838  -32.493 3.710   1.00 45.01  ? 3   ILE B O   1 
ATOM   2441  C CB  . ILE B 2 3   ? -43.576  -33.638 6.515   1.00 41.05  ? 3   ILE B CB  1 
ATOM   2442  C CG1 . ILE B 2 3   ? -42.769  -34.899 6.203   1.00 44.48  ? 3   ILE B CG1 1 
ATOM   2443  C CG2 . ILE B 2 3   ? -44.987  -33.944 6.983   1.00 44.33  ? 3   ILE B CG2 1 
ATOM   2444  C CD1 . ILE B 2 3   ? -42.104  -35.508 7.401   1.00 39.39  ? 3   ILE B CD1 1 
ATOM   2445  N N   . PHE B 2 4   ? -41.397  -31.771 5.809   1.00 38.66  ? 4   PHE B N   1 
ATOM   2446  C CA  . PHE B 2 4   ? -40.019  -31.363 5.482   1.00 35.14  ? 4   PHE B CA  1 
ATOM   2447  C C   . PHE B 2 4   ? -39.060  -32.127 6.383   1.00 38.54  ? 4   PHE B C   1 
ATOM   2448  O O   . PHE B 2 4   ? -39.400  -32.380 7.530   1.00 36.96  ? 4   PHE B O   1 
ATOM   2449  C CB  . PHE B 2 4   ? -39.886  -29.850 5.626   1.00 42.66  ? 4   PHE B CB  1 
ATOM   2450  C CG  . PHE B 2 4   ? -40.643  -29.055 4.599   1.00 43.01  ? 4   PHE B CG  1 
ATOM   2451  C CD1 . PHE B 2 4   ? -40.459  -29.285 3.247   1.00 41.17  ? 4   PHE B CD1 1 
ATOM   2452  C CD2 . PHE B 2 4   ? -41.542  -28.082 4.987   1.00 42.30  ? 4   PHE B CD2 1 
ATOM   2453  C CE1 . PHE B 2 4   ? -41.157  -28.554 2.303   1.00 39.75  ? 4   PHE B CE1 1 
ATOM   2454  C CE2 . PHE B 2 4   ? -42.243  -27.357 4.041   1.00 42.34  ? 4   PHE B CE2 1 
ATOM   2455  C CZ  . PHE B 2 4   ? -42.048  -27.591 2.702   1.00 42.57  ? 4   PHE B CZ  1 
ATOM   2456  N N   . VAL B 2 5   ? -37.936  -32.566 5.828   1.00 37.07  ? 5   VAL B N   1 
ATOM   2457  C CA  . VAL B 2 5   ? -36.893  -33.234 6.654   1.00 40.98  ? 5   VAL B CA  1 
ATOM   2458  C C   . VAL B 2 5   ? -35.571  -32.517 6.399   1.00 43.81  ? 5   VAL B C   1 
ATOM   2459  O O   . VAL B 2 5   ? -35.122  -32.513 5.257   1.00 43.40  ? 5   VAL B O   1 
ATOM   2460  C CB  . VAL B 2 5   ? -36.767  -34.750 6.407   1.00 39.51  ? 5   VAL B CB  1 
ATOM   2461  C CG1 . VAL B 2 5   ? -35.840  -35.402 7.420   1.00 33.92  ? 5   VAL B CG1 1 
ATOM   2462  C CG2 . VAL B 2 5   ? -38.107  -35.462 6.387   1.00 37.19  ? 5   VAL B CG2 1 
ATOM   2463  N N   . LYS B 2 6   ? -35.016  -31.882 7.428   1.00 42.81  ? 6   LYS B N   1 
ATOM   2464  C CA  . LYS B 2 6   ? -33.678  -31.257 7.317   1.00 44.88  ? 6   LYS B CA  1 
ATOM   2465  C C   . LYS B 2 6   ? -32.645  -32.375 7.421   1.00 49.02  ? 6   LYS B C   1 
ATOM   2466  O O   . LYS B 2 6   ? -32.703  -33.136 8.389   1.00 48.78  ? 6   LYS B O   1 
ATOM   2467  C CB  . LYS B 2 6   ? -33.491  -30.188 8.392   1.00 44.93  ? 6   LYS B CB  1 
ATOM   2468  C CG  . LYS B 2 6   ? -33.549  -28.746 7.915   1.00 48.24  ? 6   LYS B CG  1 
ATOM   2469  C CD  . LYS B 2 6   ? -33.005  -27.783 8.942   1.00 54.75  ? 6   LYS B CD  1 
ATOM   2470  C CE  . LYS B 2 6   ? -33.042  -26.338 8.495   1.00 59.13  ? 6   LYS B CE  1 
ATOM   2471  N NZ  . LYS B 2 6   ? -31.732  -25.672 8.685   1.00 57.57  ? 6   LYS B NZ  1 
ATOM   2472  N N   . THR B 2 7   ? -31.726  -32.445 6.464   1.00 45.70  ? 7   THR B N   1 
ATOM   2473  C CA  . THR B 2 7   ? -30.768  -33.568 6.402   1.00 41.12  ? 7   THR B CA  1 
ATOM   2474  C C   . THR B 2 7   ? -29.501  -33.296 7.201   1.00 46.44  ? 7   THR B C   1 
ATOM   2475  O O   . THR B 2 7   ? -29.424  -32.254 7.860   1.00 51.67  ? 7   THR B O   1 
ATOM   2476  C CB  . THR B 2 7   ? -30.424  -33.847 4.942   1.00 48.66  ? 7   THR B CB  1 
ATOM   2477  O OG1 . THR B 2 7   ? -29.730  -32.715 4.424   1.00 50.82  ? 7   THR B OG1 1 
ATOM   2478  C CG2 . THR B 2 7   ? -31.655  -34.109 4.109   1.00 46.01  ? 7   THR B CG2 1 
ATOM   2479  N N   . LEU B 2 8   ? -28.537  -34.208 7.108   1.00 50.16  ? 8   LEU B N   1 
ATOM   2480  C CA  . LEU B 2 8   ? -27.268  -34.077 7.862   1.00 42.66  ? 8   LEU B CA  1 
ATOM   2481  C C   . LEU B 2 8   ? -26.446  -32.945 7.263   1.00 48.62  ? 8   LEU B C   1 
ATOM   2482  O O   . LEU B 2 8   ? -25.486  -32.530 7.921   1.00 59.08  ? 8   LEU B O   1 
ATOM   2483  C CB  . LEU B 2 8   ? -26.526  -35.410 7.796   1.00 47.41  ? 8   LEU B CB  1 
ATOM   2484  C CG  . LEU B 2 8   ? -27.337  -36.635 8.202   1.00 43.95  ? 8   LEU B CG  1 
ATOM   2485  C CD1 . LEU B 2 8   ? -26.630  -37.905 7.769   1.00 47.94  ? 8   LEU B CD1 1 
ATOM   2486  C CD2 . LEU B 2 8   ? -27.586  -36.643 9.698   1.00 44.36  ? 8   LEU B CD2 1 
ATOM   2487  N N   . THR B 2 9   ? -26.814  -32.469 6.074   1.00 49.63  ? 9   THR B N   1 
ATOM   2488  C CA  . THR B 2 9   ? -26.146  -31.302 5.451   1.00 50.78  ? 9   THR B CA  1 
ATOM   2489  C C   . THR B 2 9   ? -26.872  -30.031 5.884   1.00 54.25  ? 9   THR B C   1 
ATOM   2490  O O   . THR B 2 9   ? -26.321  -28.947 5.666   1.00 58.98  ? 9   THR B O   1 
ATOM   2491  C CB  . THR B 2 9   ? -26.146  -31.438 3.928   1.00 52.41  ? 9   THR B CB  1 
ATOM   2492  O OG1 . THR B 2 9   ? -27.496  -31.485 3.469   1.00 56.99  ? 9   THR B OG1 1 
ATOM   2493  C CG2 . THR B 2 9   ? -25.418  -32.677 3.457   1.00 57.17  ? 9   THR B CG2 1 
ATOM   2494  N N   . GLY B 2 10  ? -28.057  -30.170 6.477   1.00 51.45  ? 10  GLY B N   1 
ATOM   2495  C CA  . GLY B 2 10  ? -28.860  -29.008 6.887   1.00 49.96  ? 10  GLY B CA  1 
ATOM   2496  C C   . GLY B 2 10  ? -29.843  -28.610 5.815   1.00 48.91  ? 10  GLY B C   1 
ATOM   2497  O O   . GLY B 2 10  ? -30.636  -27.695 6.058   1.00 54.33  ? 10  GLY B O   1 
ATOM   2498  N N   . LYS B 2 11  ? -29.783  -29.273 4.667   1.00 46.03  ? 11  LYS B N   1 
ATOM   2499  C CA  . LYS B 2 11  ? -30.674  -28.939 3.539   1.00 44.28  ? 11  LYS B CA  1 
ATOM   2500  C C   . LYS B 2 11  ? -32.050  -29.540 3.790   1.00 46.22  ? 11  LYS B C   1 
ATOM   2501  O O   . LYS B 2 11  ? -32.124  -30.632 4.345   1.00 41.99  ? 11  LYS B O   1 
ATOM   2502  C CB  . LYS B 2 11  ? -30.088  -29.467 2.233   1.00 39.33  ? 11  LYS B CB  1 
ATOM   2503  N N   . THR B 2 12  ? -33.092  -28.822 3.385   1.00 46.40  ? 12  THR B N   1 
ATOM   2504  C CA  . THR B 2 12  ? -34.469  -29.332 3.539   1.00 43.07  ? 12  THR B CA  1 
ATOM   2505  C C   . THR B 2 12  ? -34.841  -30.178 2.332   1.00 43.17  ? 12  THR B C   1 
ATOM   2506  O O   . THR B 2 12  ? -34.707  -29.688 1.204   1.00 42.04  ? 12  THR B O   1 
ATOM   2507  C CB  . THR B 2 12  ? -35.484  -28.201 3.701   1.00 41.88  ? 12  THR B CB  1 
ATOM   2508  O OG1 . THR B 2 12  ? -35.181  -27.508 4.911   1.00 50.30  ? 12  THR B OG1 1 
ATOM   2509  C CG2 . THR B 2 12  ? -36.909  -28.695 3.747   1.00 41.48  ? 12  THR B CG2 1 
ATOM   2510  N N   . ILE B 2 13  ? -35.226  -31.423 2.580   1.00 41.73  ? 13  ILE B N   1 
ATOM   2511  C CA  . ILE B 2 13  ? -35.759  -32.266 1.485   1.00 42.83  ? 13  ILE B CA  1 
ATOM   2512  C C   . ILE B 2 13  ? -37.254  -32.413 1.755   1.00 39.88  ? 13  ILE B C   1 
ATOM   2513  O O   . ILE B 2 13  ? -37.680  -32.212 2.901   1.00 39.92  ? 13  ILE B O   1 
ATOM   2514  C CB  . ILE B 2 13  ? -35.038  -33.624 1.363   1.00 37.27  ? 13  ILE B CB  1 
ATOM   2515  C CG1 . ILE B 2 13  ? -35.149  -34.470 2.634   1.00 43.17  ? 13  ILE B CG1 1 
ATOM   2516  C CG2 . ILE B 2 13  ? -33.595  -33.427 0.931   1.00 38.41  ? 13  ILE B CG2 1 
ATOM   2517  C CD1 . ILE B 2 13  ? -35.742  -35.836 2.412   1.00 34.42  ? 13  ILE B CD1 1 
ATOM   2518  N N   . THR B 2 14  ? -38.033  -32.672 0.718   1.00 41.25  ? 14  THR B N   1 
ATOM   2519  C CA  . THR B 2 14  ? -39.479  -32.898 0.910   1.00 37.67  ? 14  THR B CA  1 
ATOM   2520  C C   . THR B 2 14  ? -39.719  -34.393 1.102   1.00 39.60  ? 14  THR B C   1 
ATOM   2521  O O   . THR B 2 14  ? -39.012  -35.191 0.508   1.00 37.23  ? 14  THR B O   1 
ATOM   2522  C CB  . THR B 2 14  ? -40.299  -32.250 -0.214  1.00 37.43  ? 14  THR B CB  1 
ATOM   2523  O OG1 . THR B 2 14  ? -40.064  -32.948 -1.435  1.00 45.45  ? 14  THR B OG1 1 
ATOM   2524  C CG2 . THR B 2 14  ? -39.990  -30.782 -0.394  1.00 50.91  ? 14  THR B CG2 1 
ATOM   2525  N N   . LEU B 2 15  ? -40.640  -34.740 1.977   1.00 33.10  ? 15  LEU B N   1 
ATOM   2526  C CA  . LEU B 2 15  ? -41.021  -36.129 2.185   1.00 32.47  ? 15  LEU B CA  1 
ATOM   2527  C C   . LEU B 2 15  ? -42.532  -36.280 2.049   1.00 41.69  ? 15  LEU B C   1 
ATOM   2528  O O   . LEU B 2 15  ? -43.295  -35.430 2.514   1.00 41.80  ? 15  LEU B O   1 
ATOM   2529  C CB  . LEU B 2 15  ? -40.555  -36.667 3.558   1.00 36.86  ? 15  LEU B CB  1 
ATOM   2530  C CG  . LEU B 2 15  ? -40.240  -38.173 3.697   1.00 36.97  ? 15  LEU B CG  1 
ATOM   2531  C CD1 . LEU B 2 15  ? -38.918  -38.543 3.020   1.00 31.52  ? 15  LEU B CD1 1 
ATOM   2532  C CD2 . LEU B 2 15  ? -40.253  -38.660 5.133   1.00 32.51  ? 15  LEU B CD2 1 
ATOM   2533  N N   . GLU B 2 16  ? -42.961  -37.384 1.414   1.00 49.38  ? 16  GLU B N   1 
ATOM   2534  C CA  . GLU B 2 16  ? -44.373  -37.643 1.120   1.00 43.64  ? 16  GLU B CA  1 
ATOM   2535  C C   . GLU B 2 16  ? -44.895  -38.675 2.113   1.00 47.13  ? 16  GLU B C   1 
ATOM   2536  O O   . GLU B 2 16  ? -44.588  -39.859 2.003   1.00 53.72  ? 16  GLU B O   1 
ATOM   2537  C CB  . GLU B 2 16  ? -44.544  -38.121 -0.313  1.00 44.77  ? 16  GLU B CB  1 
ATOM   2538  C CG  . GLU B 2 16  ? -45.988  -38.286 -0.704  1.00 50.62  ? 16  GLU B CG  1 
ATOM   2539  C CD  . GLU B 2 16  ? -46.817  -37.080 -0.326  1.00 57.45  ? 16  GLU B CD  1 
ATOM   2540  O OE1 . GLU B 2 16  ? -46.419  -35.929 -0.681  1.00 49.41  ? 16  GLU B OE1 1 
ATOM   2541  O OE2 . GLU B 2 16  ? -47.870  -37.302 0.324   1.00 61.42  ? 16  GLU B OE2 1 
ATOM   2542  N N   . VAL B 2 17  ? -45.694  -38.239 3.085   1.00 47.34  ? 17  VAL B N   1 
ATOM   2543  C CA  . VAL B 2 17  ? -46.034  -39.097 4.213   1.00 53.90  ? 17  VAL B CA  1 
ATOM   2544  C C   . VAL B 2 17  ? -47.523  -39.017 4.554   1.00 57.87  ? 17  VAL B C   1 
ATOM   2545  O O   . VAL B 2 17  ? -48.263  -38.143 4.092   1.00 49.12  ? 17  VAL B O   1 
ATOM   2546  C CB  . VAL B 2 17  ? -45.197  -38.758 5.451   1.00 53.81  ? 17  VAL B CB  1 
ATOM   2547  C CG1 . VAL B 2 17  ? -43.779  -39.257 5.251   1.00 48.72  ? 17  VAL B CG1 1 
ATOM   2548  C CG2 . VAL B 2 17  ? -45.250  -37.256 5.690   1.00 55.87  ? 17  VAL B CG2 1 
ATOM   2549  N N   . GLU B 2 18  ? -47.945  -39.963 5.394   1.00 56.14  ? 18  GLU B N   1 
ATOM   2550  C CA  . GLU B 2 18  ? -49.331  -40.111 5.787   1.00 59.71  ? 18  GLU B CA  1 
ATOM   2551  C C   . GLU B 2 18  ? -49.485  -40.075 7.306   1.00 56.19  ? 18  GLU B C   1 
ATOM   2552  O O   . GLU B 2 18  ? -48.705  -40.711 8.021   1.00 57.48  ? 18  GLU B O   1 
ATOM   2553  C CB  . GLU B 2 18  ? -49.903  -41.424 5.241   1.00 59.88  ? 18  GLU B CB  1 
ATOM   2554  C CG  . GLU B 2 18  ? -50.446  -41.279 3.821   1.00 59.95  ? 18  GLU B CG  1 
ATOM   2555  C CD  . GLU B 2 18  ? -51.675  -40.374 3.745   1.00 60.99  ? 18  GLU B CD  1 
ATOM   2556  O OE1 . GLU B 2 18  ? -52.707  -40.740 4.354   1.00 60.64  ? 18  GLU B OE1 1 
ATOM   2557  O OE2 . GLU B 2 18  ? -51.612  -39.311 3.071   1.00 64.08  ? 18  GLU B OE2 1 
ATOM   2558  N N   . PRO B 2 19  ? -50.474  -39.335 7.824   1.00 55.16  ? 19  PRO B N   1 
ATOM   2559  C CA  . PRO B 2 19  ? -50.756  -39.380 9.269   1.00 53.13  ? 19  PRO B CA  1 
ATOM   2560  C C   . PRO B 2 19  ? -50.784  -40.785 9.835   1.00 56.49  ? 19  PRO B C   1 
ATOM   2561  O O   . PRO B 2 19  ? -50.455  -41.000 11.003  1.00 56.25  ? 19  PRO B O   1 
ATOM   2562  C CB  . PRO B 2 19  ? -52.131  -38.714 9.362   1.00 49.82  ? 19  PRO B CB  1 
ATOM   2563  C CG  . PRO B 2 19  ? -52.125  -37.700 8.223   1.00 45.54  ? 19  PRO B CG  1 
ATOM   2564  C CD  . PRO B 2 19  ? -51.327  -38.358 7.116   1.00 55.76  ? 19  PRO B CD  1 
ATOM   2565  N N   . SER B 2 20  ? -51.169  -41.764 9.035   1.00 63.82  ? 20  SER B N   1 
ATOM   2566  C CA  . SER B 2 20  ? -51.058  -43.158 9.447   1.00 57.63  ? 20  SER B CA  1 
ATOM   2567  C C   . SER B 2 20  ? -49.630  -43.642 9.651   1.00 59.40  ? 20  SER B C   1 
ATOM   2568  O O   . SER B 2 20  ? -49.425  -44.548 10.471  1.00 62.54  ? 20  SER B O   1 
ATOM   2569  C CB  . SER B 2 20  ? -51.681  -44.043 8.391   1.00 57.61  ? 20  SER B CB  1 
ATOM   2570  O OG  . SER B 2 20  ? -51.111  -43.744 7.113   1.00 76.39  ? 20  SER B OG  1 
ATOM   2571  N N   . ASP B 2 21  ? -48.639  -43.055 8.969   1.00 58.39  ? 21  ASP B N   1 
ATOM   2572  C CA  . ASP B 2 21  ? -47.311  -43.658 8.907   1.00 55.30  ? 21  ASP B CA  1 
ATOM   2573  C C   . ASP B 2 21  ? -46.704  -43.783 10.292  1.00 52.67  ? 21  ASP B C   1 
ATOM   2574  O O   . ASP B 2 21  ? -46.714  -42.842 11.082  1.00 58.91  ? 21  ASP B O   1 
ATOM   2575  C CB  . ASP B 2 21  ? -46.376  -42.842 8.012   1.00 51.64  ? 21  ASP B CB  1 
ATOM   2576  C CG  . ASP B 2 21  ? -46.804  -42.843 6.526   1.00 61.32  ? 21  ASP B CG  1 
ATOM   2577  O OD1 . ASP B 2 21  ? -47.487  -43.808 6.078   1.00 63.50  ? 21  ASP B OD1 1 
ATOM   2578  O OD2 . ASP B 2 21  ? -46.476  -41.854 5.817   1.00 52.37  ? 21  ASP B OD2 1 
ATOM   2579  N N   . THR B 2 22  ? -46.070  -44.924 10.522  1.00 53.82  ? 22  THR B N   1 
ATOM   2580  C CA  . THR B 2 22  ? -45.309  -45.092 11.775  1.00 55.88  ? 22  THR B CA  1 
ATOM   2581  C C   . THR B 2 22  ? -43.943  -44.437 11.569  1.00 49.72  ? 22  THR B C   1 
ATOM   2582  O O   . THR B 2 22  ? -43.649  -44.001 10.452  1.00 44.85  ? 22  THR B O   1 
ATOM   2583  C CB  . THR B 2 22  ? -45.212  -46.573 12.146  1.00 59.26  ? 22  THR B CB  1 
ATOM   2584  O OG1 . THR B 2 22  ? -44.517  -47.257 11.108  1.00 56.66  ? 22  THR B OG1 1 
ATOM   2585  C CG2 . THR B 2 22  ? -46.565  -47.213 12.351  1.00 51.44  ? 22  THR B CG2 1 
ATOM   2586  N N   . ILE B 2 23  ? -43.131  -44.379 12.613  1.00 48.63  ? 23  ILE B N   1 
ATOM   2587  C CA  . ILE B 2 23  ? -41.827  -43.669 12.496  1.00 49.50  ? 23  ILE B CA  1 
ATOM   2588  C C   . ILE B 2 23  ? -40.878  -44.549 11.679  1.00 54.20  ? 23  ILE B C   1 
ATOM   2589  O O   . ILE B 2 23  ? -40.062  -43.992 10.951  1.00 51.54  ? 23  ILE B O   1 
ATOM   2590  C CB  . ILE B 2 23  ? -41.311  -43.267 13.892  1.00 48.22  ? 23  ILE B CB  1 
ATOM   2591  C CG1 . ILE B 2 23  ? -42.317  -42.367 14.616  1.00 47.38  ? 23  ILE B CG1 1 
ATOM   2592  C CG2 . ILE B 2 23  ? -39.941  -42.616 13.826  1.00 49.73  ? 23  ILE B CG2 1 
ATOM   2593  C CD1 . ILE B 2 23  ? -42.947  -41.302 13.754  1.00 47.33  ? 23  ILE B CD1 1 
ATOM   2594  N N   . GLU B 2 24  ? -41.032  -45.869 11.743  1.00 54.26  ? 24  GLU B N   1 
ATOM   2595  C CA  . GLU B 2 24  ? -40.223  -46.785 10.900  1.00 48.02  ? 24  GLU B CA  1 
ATOM   2596  C C   . GLU B 2 24  ? -40.628  -46.598 9.436   1.00 49.10  ? 24  GLU B C   1 
ATOM   2597  O O   . GLU B 2 24  ? -39.734  -46.665 8.592   1.00 47.32  ? 24  GLU B O   1 
ATOM   2598  C CB  . GLU B 2 24  ? -40.351  -48.222 11.406  1.00 46.53  ? 24  GLU B CB  1 
ATOM   2599  C CG  . GLU B 2 24  ? -41.739  -48.626 11.850  1.00 63.98  ? 24  GLU B CG  1 
ATOM   2600  C CD  . GLU B 2 24  ? -41.988  -48.523 13.343  1.00 66.92  ? 24  GLU B CD  1 
ATOM   2601  O OE1 . GLU B 2 24  ? -42.300  -47.418 13.802  1.00 64.37  ? 24  GLU B OE1 1 
ATOM   2602  O OE2 . GLU B 2 24  ? -41.873  -49.548 14.035  1.00 65.23  ? 24  GLU B OE2 1 
ATOM   2603  N N   . ASN B 2 25  ? -41.916  -46.398 9.143   1.00 50.12  ? 25  ASN B N   1 
ATOM   2604  C CA  . ASN B 2 25  ? -42.321  -46.066 7.771   1.00 47.32  ? 25  ASN B CA  1 
ATOM   2605  C C   . ASN B 2 25  ? -41.701  -44.757 7.304   1.00 50.86  ? 25  ASN B C   1 
ATOM   2606  O O   . ASN B 2 25  ? -41.270  -44.647 6.147   1.00 55.57  ? 25  ASN B O   1 
ATOM   2607  C CB  . ASN B 2 25  ? -43.843  -45.946 7.632   1.00 52.82  ? 25  ASN B CB  1 
ATOM   2608  C CG  . ASN B 2 25  ? -44.585  -47.229 7.962   1.00 59.05  ? 25  ASN B CG  1 
ATOM   2609  O OD1 . ASN B 2 25  ? -45.674  -47.181 8.547   1.00 62.42  ? 25  ASN B OD1 1 
ATOM   2610  N ND2 . ASN B 2 25  ? -44.019  -48.378 7.580   1.00 55.24  ? 25  ASN B ND2 1 
ATOM   2611  N N   . VAL B 2 26  ? -41.692  -43.733 8.170   1.00 48.92  ? 26  VAL B N   1 
ATOM   2612  C CA  . VAL B 2 26  ? -41.087  -42.456 7.799   1.00 43.70  ? 26  VAL B CA  1 
ATOM   2613  C C   . VAL B 2 26  ? -39.596  -42.634 7.575   1.00 43.91  ? 26  VAL B C   1 
ATOM   2614  O O   . VAL B 2 26  ? -39.039  -42.109 6.606   1.00 41.79  ? 26  VAL B O   1 
ATOM   2615  C CB  . VAL B 2 26  ? -41.367  -41.377 8.867   1.00 43.67  ? 26  VAL B CB  1 
ATOM   2616  C CG1 . VAL B 2 26  ? -40.417  -40.198 8.695   1.00 39.45  ? 26  VAL B CG1 1 
ATOM   2617  C CG2 . VAL B 2 26  ? -42.788  -40.867 8.772   1.00 45.85  ? 26  VAL B CG2 1 
ATOM   2618  N N   . LYS B 2 27  ? -38.928  -43.389 8.465   1.00 46.68  ? 27  LYS B N   1 
ATOM   2619  C CA  . LYS B 2 27  ? -37.481  -43.569 8.352   1.00 50.81  ? 27  LYS B CA  1 
ATOM   2620  C C   . LYS B 2 27  ? -37.108  -44.262 7.049   1.00 49.86  ? 27  LYS B C   1 
ATOM   2621  O O   . LYS B 2 27  ? -36.040  -43.991 6.479   1.00 46.87  ? 27  LYS B O   1 
ATOM   2622  C CB  . LYS B 2 27  ? -36.936  -44.377 9.531   1.00 47.52  ? 27  LYS B CB  1 
ATOM   2623  C CG  . LYS B 2 27  ? -36.799  -43.625 10.847  1.00 44.26  ? 27  LYS B CG  1 
ATOM   2624  C CD  . LYS B 2 27  ? -36.478  -44.610 11.984  1.00 49.00  ? 27  LYS B CD  1 
ATOM   2625  C CE  . LYS B 2 27  ? -36.398  -43.953 13.361  1.00 43.67  ? 27  LYS B CE  1 
ATOM   2626  N NZ  . LYS B 2 27  ? -35.852  -44.894 14.389  1.00 38.06  ? 27  LYS B NZ  1 
ATOM   2627  N N   . ALA B 2 28  ? -37.985  -45.141 6.555   1.00 46.86  ? 28  ALA B N   1 
ATOM   2628  C CA  . ALA B 2 28  ? -37.686  -45.856 5.323   1.00 47.54  ? 28  ALA B CA  1 
ATOM   2629  C C   . ALA B 2 28  ? -37.824  -44.939 4.128   1.00 46.98  ? 28  ALA B C   1 
ATOM   2630  O O   . ALA B 2 28  ? -37.015  -44.995 3.194   1.00 53.60  ? 28  ALA B O   1 
ATOM   2631  C CB  . ALA B 2 28  ? -38.596  -47.073 5.179   1.00 40.97  ? 28  ALA B CB  1 
ATOM   2632  N N   . LYS B 2 29  ? -38.839  -44.085 4.136   1.00 44.06  ? 29  LYS B N   1 
ATOM   2633  C CA  . LYS B 2 29  ? -38.939  -43.085 3.087   1.00 43.57  ? 29  LYS B CA  1 
ATOM   2634  C C   . LYS B 2 29  ? -37.696  -42.203 3.054   1.00 43.19  ? 29  LYS B C   1 
ATOM   2635  O O   . LYS B 2 29  ? -37.182  -41.889 1.974   1.00 43.52  ? 29  LYS B O   1 
ATOM   2636  C CB  . LYS B 2 29  ? -40.227  -42.288 3.292   1.00 49.51  ? 29  LYS B CB  1 
ATOM   2637  C CG  . LYS B 2 29  ? -41.479  -43.185 3.145   1.00 41.36  ? 29  LYS B CG  1 
ATOM   2638  C CD  . LYS B 2 29  ? -42.698  -42.595 3.810   1.00 47.36  ? 29  LYS B CD  1 
ATOM   2639  C CE  . LYS B 2 29  ? -43.983  -43.027 3.104   1.00 49.83  ? 29  LYS B CE  1 
ATOM   2640  N NZ  . LYS B 2 29  ? -43.879  -42.888 1.606   1.00 54.71  ? 29  LYS B NZ  1 
ATOM   2641  N N   . ILE B 2 30  ? -37.151  -41.858 4.225   1.00 42.70  ? 30  ILE B N   1 
ATOM   2642  C CA  . ILE B 2 30  ? -35.892  -41.114 4.273   1.00 41.27  ? 30  ILE B CA  1 
ATOM   2643  C C   . ILE B 2 30  ? -34.760  -41.919 3.641   1.00 42.03  ? 30  ILE B C   1 
ATOM   2644  O O   . ILE B 2 30  ? -33.958  -41.388 2.864   1.00 42.18  ? 30  ILE B O   1 
ATOM   2645  C CB  . ILE B 2 30  ? -35.543  -40.716 5.717   1.00 44.91  ? 30  ILE B CB  1 
ATOM   2646  C CG1 . ILE B 2 30  ? -36.623  -39.803 6.292   1.00 44.44  ? 30  ILE B CG1 1 
ATOM   2647  C CG2 . ILE B 2 30  ? -34.156  -40.031 5.755   1.00 37.30  ? 30  ILE B CG2 1 
ATOM   2648  C CD1 . ILE B 2 30  ? -36.456  -39.472 7.758   1.00 40.81  ? 30  ILE B CD1 1 
ATOM   2649  N N   . GLN B 2 31  ? -34.641  -43.200 4.002   1.00 44.20  ? 31  GLN B N   1 
ATOM   2650  C CA  . GLN B 2 31  ? -33.630  -44.030 3.350   1.00 47.07  ? 31  GLN B CA  1 
ATOM   2651  C C   . GLN B 2 31  ? -33.836  -44.036 1.838   1.00 50.17  ? 31  GLN B C   1 
ATOM   2652  O O   . GLN B 2 31  ? -32.875  -43.914 1.070   1.00 48.98  ? 31  GLN B O   1 
ATOM   2653  C CB  . GLN B 2 31  ? -33.666  -45.452 3.911   1.00 51.43  ? 31  GLN B CB  1 
ATOM   2654  C CG  . GLN B 2 31  ? -32.962  -46.517 3.031   1.00 59.35  ? 31  GLN B CG  1 
ATOM   2655  C CD  . GLN B 2 31  ? -33.279  -47.964 3.457   1.00 64.75  ? 31  GLN B CD  1 
ATOM   2656  O OE1 . GLN B 2 31  ? -34.325  -48.245 4.069   1.00 72.33  ? 31  GLN B OE1 1 
ATOM   2657  N NE2 . GLN B 2 31  ? -32.376  -48.881 3.127   1.00 58.88  ? 31  GLN B NE2 1 
ATOM   2658  N N   . ASP B 2 32  ? -35.095  -44.114 1.402   1.00 40.13  ? 32  ASP B N   1 
ATOM   2659  C CA  . ASP B 2 32  ? -35.400  -44.128 -0.010  1.00 32.00  ? 32  ASP B CA  1 
ATOM   2660  C C   . ASP B 2 32  ? -34.961  -42.848 -0.711  1.00 41.33  ? 32  ASP B C   1 
ATOM   2661  O O   . ASP B 2 32  ? -34.652  -42.879 -1.905  1.00 47.46  ? 32  ASP B O   1 
ATOM   2662  C CB  . ASP B 2 32  ? -36.884  -44.365 -0.172  1.00 33.38  ? 32  ASP B CB  1 
ATOM   2663  C CG  . ASP B 2 32  ? -37.370  -44.035 -1.537  1.00 41.39  ? 32  ASP B CG  1 
ATOM   2664  O OD1 . ASP B 2 32  ? -37.609  -42.836 -1.791  1.00 42.75  ? 32  ASP B OD1 1 
ATOM   2665  O OD2 . ASP B 2 32  ? -37.533  -44.970 -2.352  1.00 52.25  ? 32  ASP B OD2 1 
ATOM   2666  N N   . LYS B 2 33  ? -34.921  -41.714 -0.008  1.00 46.14  ? 33  LYS B N   1 
ATOM   2667  C CA  . LYS B 2 33  ? -34.578  -40.431 -0.625  1.00 38.83  ? 33  LYS B CA  1 
ATOM   2668  C C   . LYS B 2 33  ? -33.190  -39.918 -0.253  1.00 44.79  ? 33  LYS B C   1 
ATOM   2669  O O   . LYS B 2 33  ? -32.568  -39.221 -1.055  1.00 47.39  ? 33  LYS B O   1 
ATOM   2670  C CB  . LYS B 2 33  ? -35.618  -39.356 -0.258  1.00 36.20  ? 33  LYS B CB  1 
ATOM   2671  C CG  . LYS B 2 33  ? -35.601  -38.129 -1.184  1.00 36.92  ? 33  LYS B CG  1 
ATOM   2672  C CD  . LYS B 2 33  ? -36.954  -37.546 -1.487  1.00 28.73  ? 33  LYS B CD  1 
ATOM   2673  C CE  . LYS B 2 33  ? -36.808  -36.023 -1.693  1.00 42.07  ? 33  LYS B CE  1 
ATOM   2674  N NZ  . LYS B 2 33  ? -38.023  -35.186 -2.070  1.00 36.55  ? 33  LYS B NZ  1 
ATOM   2675  N N   . GLU B 2 34  ? -32.677  -40.239 0.930   1.00 43.08  ? 34  GLU B N   1 
ATOM   2676  C CA  . GLU B 2 34  ? -31.363  -39.772 1.340   1.00 44.25  ? 34  GLU B CA  1 
ATOM   2677  C C   . GLU B 2 34  ? -30.351  -40.897 1.489   1.00 51.26  ? 34  GLU B C   1 
ATOM   2678  O O   . GLU B 2 34  ? -29.159  -40.616 1.628   1.00 49.85  ? 34  GLU B O   1 
ATOM   2679  C CB  . GLU B 2 34  ? -31.463  -39.016 2.672   1.00 45.91  ? 34  GLU B CB  1 
ATOM   2680  C CG  . GLU B 2 34  ? -31.760  -37.567 2.517   1.00 43.14  ? 34  GLU B CG  1 
ATOM   2681  C CD  . GLU B 2 34  ? -30.644  -36.836 1.797   1.00 52.28  ? 34  GLU B CD  1 
ATOM   2682  O OE1 . GLU B 2 34  ? -29.560  -36.650 2.401   1.00 50.63  ? 34  GLU B OE1 1 
ATOM   2683  O OE2 . GLU B 2 34  ? -30.855  -36.460 0.617   1.00 60.26  ? 34  GLU B OE2 1 
ATOM   2684  N N   . GLY B 2 35  ? -30.792  -42.154 1.491   1.00 46.64  ? 35  GLY B N   1 
ATOM   2685  C CA  . GLY B 2 35  ? -29.885  -43.258 1.591   1.00 40.06  ? 35  GLY B CA  1 
ATOM   2686  C C   . GLY B 2 35  ? -29.481  -43.616 2.995   1.00 56.81  ? 35  GLY B C   1 
ATOM   2687  O O   . GLY B 2 35  ? -28.681  -44.546 3.175   1.00 61.93  ? 35  GLY B O   1 
ATOM   2688  N N   . ILE B 2 36  ? -29.990  -42.911 3.998   1.00 52.28  ? 36  ILE B N   1 
ATOM   2689  C CA  . ILE B 2 36  ? -29.599  -43.216 5.365   1.00 52.07  ? 36  ILE B CA  1 
ATOM   2690  C C   . ILE B 2 36  ? -30.306  -44.476 5.839   1.00 53.99  ? 36  ILE B C   1 
ATOM   2691  O O   . ILE B 2 36  ? -31.542  -44.502 5.924   1.00 50.79  ? 36  ILE B O   1 
ATOM   2692  C CB  . ILE B 2 36  ? -29.895  -42.058 6.319   1.00 51.57  ? 36  ILE B CB  1 
ATOM   2693  C CG1 . ILE B 2 36  ? -29.452  -40.708 5.704   1.00 49.54  ? 36  ILE B CG1 1 
ATOM   2694  C CG2 . ILE B 2 36  ? -29.260  -42.371 7.677   1.00 47.38  ? 36  ILE B CG2 1 
ATOM   2695  C CD1 . ILE B 2 36  ? -28.007  -40.657 5.249   1.00 56.07  ? 36  ILE B CD1 1 
ATOM   2696  N N   . PRO B 2 37  ? -29.563  -45.524 6.177   1.00 57.19  ? 37  PRO B N   1 
ATOM   2697  C CA  . PRO B 2 37  ? -30.169  -46.720 6.760   1.00 55.46  ? 37  PRO B CA  1 
ATOM   2698  C C   . PRO B 2 37  ? -30.992  -46.378 7.990   1.00 52.22  ? 37  PRO B C   1 
ATOM   2699  O O   . PRO B 2 37  ? -30.527  -45.645 8.878   1.00 52.13  ? 37  PRO B O   1 
ATOM   2700  C CB  . PRO B 2 37  ? -28.954  -47.581 7.134   1.00 57.39  ? 37  PRO B CB  1 
ATOM   2701  C CG  . PRO B 2 37  ? -27.872  -47.100 6.265   1.00 54.30  ? 37  PRO B CG  1 
ATOM   2702  C CD  . PRO B 2 37  ? -28.101  -45.635 6.107   1.00 57.84  ? 37  PRO B CD  1 
ATOM   2703  N N   . PRO B 2 38  ? -32.223  -46.887 8.069   1.00 51.93  ? 38  PRO B N   1 
ATOM   2704  C CA  . PRO B 2 38  ? -33.065  -46.589 9.236   1.00 46.95  ? 38  PRO B CA  1 
ATOM   2705  C C   . PRO B 2 38  ? -32.420  -46.906 10.574  1.00 49.03  ? 38  PRO B C   1 
ATOM   2706  O O   . PRO B 2 38  ? -32.628  -46.144 11.522  1.00 48.70  ? 38  PRO B O   1 
ATOM   2707  C CB  . PRO B 2 38  ? -34.305  -47.446 8.974   1.00 52.86  ? 38  PRO B CB  1 
ATOM   2708  C CG  . PRO B 2 38  ? -34.383  -47.521 7.438   1.00 45.68  ? 38  PRO B CG  1 
ATOM   2709  C CD  . PRO B 2 38  ? -32.971  -47.553 6.979   1.00 48.80  ? 38  PRO B CD  1 
ATOM   2710  N N   . ASP B 2 39  ? -31.610  -47.944 10.676  1.00 58.66  ? 39  ASP B N   1 
ATOM   2711  C CA  . ASP B 2 39  ? -31.066  -48.318 12.008  1.00 61.25  ? 39  ASP B CA  1 
ATOM   2712  C C   . ASP B 2 39  ? -30.263  -47.169 12.628  1.00 55.37  ? 39  ASP B C   1 
ATOM   2713  O O   . ASP B 2 39  ? -29.976  -47.261 13.825  1.00 56.02  ? 39  ASP B O   1 
ATOM   2714  C CB  . ASP B 2 39  ? -30.236  -49.600 11.906  1.00 69.64  ? 39  ASP B CB  1 
ATOM   2715  C CG  . ASP B 2 39  ? -30.102  -50.152 10.499  1.00 86.17  ? 39  ASP B CG  1 
ATOM   2716  O OD1 . ASP B 2 39  ? -29.021  -49.982 9.910   1.00 78.63  ? 39  ASP B OD1 1 
ATOM   2717  O OD2 . ASP B 2 39  ? -31.079  -50.748 10.008  1.00 82.32  ? 39  ASP B OD2 1 
ATOM   2718  N N   . GLN B 2 40  ? -29.947  -46.117 11.869  1.00 51.51  ? 40  GLN B N   1 
ATOM   2719  C CA  . GLN B 2 40  ? -29.081  -45.053 12.339  1.00 49.16  ? 40  GLN B CA  1 
ATOM   2720  C C   . GLN B 2 40  ? -29.746  -43.691 12.354  1.00 47.33  ? 40  GLN B C   1 
ATOM   2721  O O   . GLN B 2 40  ? -29.124  -42.712 12.782  1.00 48.33  ? 40  GLN B O   1 
ATOM   2722  C CB  . GLN B 2 40  ? -27.828  -44.998 11.471  1.00 51.22  ? 40  GLN B CB  1 
ATOM   2723  C CG  . GLN B 2 40  ? -27.411  -46.374 11.033  1.00 59.97  ? 40  GLN B CG  1 
ATOM   2724  C CD  . GLN B 2 40  ? -26.212  -46.335 10.141  1.00 71.75  ? 40  GLN B CD  1 
ATOM   2725  O OE1 . GLN B 2 40  ? -25.447  -45.359 10.153  1.00 71.29  ? 40  GLN B OE1 1 
ATOM   2726  N NE2 . GLN B 2 40  ? -26.028  -47.395 9.349   1.00 75.70  ? 40  GLN B NE2 1 
ATOM   2727  N N   . GLN B 2 41  ? -30.987  -43.599 11.922  1.00 43.61  ? 41  GLN B N   1 
ATOM   2728  C CA  . GLN B 2 41  ? -31.687  -42.333 11.946  1.00 44.60  ? 41  GLN B CA  1 
ATOM   2729  C C   . GLN B 2 41  ? -32.243  -42.055 13.337  1.00 44.21  ? 41  GLN B C   1 
ATOM   2730  O O   . GLN B 2 41  ? -32.865  -42.925 13.948  1.00 44.45  ? 41  GLN B O   1 
ATOM   2731  C CB  . GLN B 2 41  ? -32.815  -42.356 10.924  1.00 39.52  ? 41  GLN B CB  1 
ATOM   2732  C CG  . GLN B 2 41  ? -32.384  -42.817 9.582   1.00 44.30  ? 41  GLN B CG  1 
ATOM   2733  C CD  . GLN B 2 41  ? -33.523  -42.757 8.599   1.00 50.51  ? 41  GLN B CD  1 
ATOM   2734  O OE1 . GLN B 2 41  ? -34.546  -42.146 8.885   1.00 49.76  ? 41  GLN B OE1 1 
ATOM   2735  N NE2 . GLN B 2 41  ? -33.360  -43.387 7.436   1.00 48.81  ? 41  GLN B NE2 1 
ATOM   2736  N N   . ARG B 2 42  ? -32.151  -40.776 13.701  1.00 40.60  ? 42  ARG B N   1 
ATOM   2737  C CA  . ARG B 2 42  ? -32.791  -40.241 14.917  1.00 39.37  ? 42  ARG B CA  1 
ATOM   2738  C C   . ARG B 2 42  ? -33.457  -38.952 14.420  1.00 41.28  ? 42  ARG B C   1 
ATOM   2739  O O   . ARG B 2 42  ? -32.745  -38.103 13.903  1.00 44.08  ? 42  ARG B O   1 
ATOM   2740  C CB  . ARG B 2 42  ? -31.774  -39.990 16.022  1.00 40.76  ? 42  ARG B CB  1 
ATOM   2741  C CG  . ARG B 2 42  ? -30.813  -41.128 16.326  1.00 42.28  ? 42  ARG B CG  1 
ATOM   2742  C CD  . ARG B 2 42  ? -29.947  -40.705 17.492  1.00 44.07  ? 42  ARG B CD  1 
ATOM   2743  N NE  . ARG B 2 42  ? -30.666  -39.695 18.231  1.00 51.11  ? 42  ARG B NE  1 
ATOM   2744  C CZ  . ARG B 2 42  ? -30.168  -38.574 18.709  1.00 50.48  ? 42  ARG B CZ  1 
ATOM   2745  N NH1 . ARG B 2 42  ? -28.880  -38.304 18.605  1.00 42.95  ? 42  ARG B NH1 1 
ATOM   2746  N NH2 . ARG B 2 42  ? -30.983  -37.746 19.327  1.00 50.23  ? 42  ARG B NH2 1 
ATOM   2747  N N   . LEU B 2 43  ? -34.765  -38.807 14.547  1.00 35.34  ? 43  LEU B N   1 
ATOM   2748  C CA  . LEU B 2 43  ? -35.555  -37.707 14.002  1.00 38.27  ? 43  LEU B CA  1 
ATOM   2749  C C   . LEU B 2 43  ? -36.093  -36.846 15.135  1.00 42.30  ? 43  LEU B C   1 
ATOM   2750  O O   . LEU B 2 43  ? -36.753  -37.368 16.045  1.00 45.42  ? 43  LEU B O   1 
ATOM   2751  C CB  . LEU B 2 43  ? -36.734  -38.248 13.200  1.00 41.32  ? 43  LEU B CB  1 
ATOM   2752  C CG  . LEU B 2 43  ? -36.417  -39.241 12.105  1.00 35.43  ? 43  LEU B CG  1 
ATOM   2753  C CD1 . LEU B 2 43  ? -37.697  -39.803 11.553  1.00 35.12  ? 43  LEU B CD1 1 
ATOM   2754  C CD2 . LEU B 2 43  ? -35.705  -38.446 11.042  1.00 43.57  ? 43  LEU B CD2 1 
ATOM   2755  N N   . ILE B 2 44  ? -35.817  -35.542 15.085  1.00 40.12  ? 44  ILE B N   1 
ATOM   2756  C CA  . ILE B 2 44  ? -36.201  -34.646 16.215  1.00 43.14  ? 44  ILE B CA  1 
ATOM   2757  C C   . ILE B 2 44  ? -37.286  -33.658 15.797  1.00 43.73  ? 44  ILE B C   1 
ATOM   2758  O O   . ILE B 2 44  ? -37.075  -32.910 14.845  1.00 44.05  ? 44  ILE B O   1 
ATOM   2759  C CB  . ILE B 2 44  ? -34.965  -33.956 16.836  1.00 42.67  ? 44  ILE B CB  1 
ATOM   2760  C CG1 . ILE B 2 44  ? -34.083  -34.960 17.580  1.00 40.24  ? 44  ILE B CG1 1 
ATOM   2761  C CG2 . ILE B 2 44  ? -35.363  -32.806 17.745  1.00 43.40  ? 44  ILE B CG2 1 
ATOM   2762  C CD1 . ILE B 2 44  ? -32.665  -35.008 17.084  1.00 46.41  ? 44  ILE B CD1 1 
ATOM   2763  N N   . PHE B 2 45  ? -38.430  -33.726 16.466  1.00 46.98  ? 45  PHE B N   1 
ATOM   2764  C CA  . PHE B 2 45  ? -39.523  -32.778 16.269  1.00 47.29  ? 45  PHE B CA  1 
ATOM   2765  C C   . PHE B 2 45  ? -39.921  -32.118 17.592  1.00 47.29  ? 45  PHE B C   1 
ATOM   2766  O O   . PHE B 2 45  ? -40.204  -32.803 18.582  1.00 41.53  ? 45  PHE B O   1 
ATOM   2767  C CB  . PHE B 2 45  ? -40.730  -33.470 15.663  1.00 43.19  ? 45  PHE B CB  1 
ATOM   2768  C CG  . PHE B 2 45  ? -41.853  -32.541 15.360  1.00 42.88  ? 45  PHE B CG  1 
ATOM   2769  C CD1 . PHE B 2 45  ? -41.714  -31.569 14.396  1.00 46.20  ? 45  PHE B CD1 1 
ATOM   2770  C CD2 . PHE B 2 45  ? -43.046  -32.638 16.031  1.00 45.73  ? 45  PHE B CD2 1 
ATOM   2771  C CE1 . PHE B 2 45  ? -42.756  -30.693 14.106  1.00 45.56  ? 45  PHE B CE1 1 
ATOM   2772  C CE2 . PHE B 2 45  ? -44.088  -31.783 15.739  1.00 43.53  ? 45  PHE B CE2 1 
ATOM   2773  C CZ  . PHE B 2 45  ? -43.937  -30.808 14.778  1.00 44.10  ? 45  PHE B CZ  1 
ATOM   2774  N N   . ALA B 2 46  ? -39.901  -30.791 17.624  1.00 46.47  ? 46  ALA B N   1 
ATOM   2775  C CA  . ALA B 2 46  ? -40.290  -30.033 18.833  1.00 42.50  ? 46  ALA B CA  1 
ATOM   2776  C C   . ALA B 2 46  ? -39.581  -30.574 20.070  1.00 43.97  ? 46  ALA B C   1 
ATOM   2777  O O   . ALA B 2 46  ? -40.199  -30.594 21.136  1.00 41.92  ? 46  ALA B O   1 
ATOM   2778  C CB  . ALA B 2 46  ? -41.785  -30.042 18.978  1.00 40.77  ? 46  ALA B CB  1 
ATOM   2779  N N   . GLY B 2 47  ? -38.319  -30.971 19.921  1.00 47.89  ? 47  GLY B N   1 
ATOM   2780  C CA  . GLY B 2 47  ? -37.573  -31.490 21.040  1.00 39.40  ? 47  GLY B CA  1 
ATOM   2781  C C   . GLY B 2 47  ? -37.956  -32.884 21.455  1.00 40.88  ? 47  GLY B C   1 
ATOM   2782  O O   . GLY B 2 47  ? -37.409  -33.390 22.442  1.00 42.38  ? 47  GLY B O   1 
ATOM   2783  N N   . LYS B 2 48  ? -38.889  -33.521 20.772  1.00 40.21  ? 48  LYS B N   1 
ATOM   2784  C CA  . LYS B 2 48  ? -39.150  -34.921 21.021  1.00 40.76  ? 48  LYS B CA  1 
ATOM   2785  C C   . LYS B 2 48  ? -38.406  -35.727 19.962  1.00 44.89  ? 48  LYS B C   1 
ATOM   2786  O O   . LYS B 2 48  ? -38.418  -35.365 18.777  1.00 47.14  ? 48  LYS B O   1 
ATOM   2787  C CB  . LYS B 2 48  ? -40.650  -35.210 21.011  1.00 44.09  ? 48  LYS B CB  1 
ATOM   2788  N N   . GLN B 2 49  ? -37.711  -36.780 20.395  1.00 39.81  ? 49  GLN B N   1 
ATOM   2789  C CA  . GLN B 2 49  ? -37.183  -37.764 19.463  1.00 43.45  ? 49  GLN B CA  1 
ATOM   2790  C C   . GLN B 2 49  ? -38.273  -38.801 19.229  1.00 43.03  ? 49  GLN B C   1 
ATOM   2791  O O   . GLN B 2 49  ? -38.770  -39.412 20.186  1.00 47.48  ? 49  GLN B O   1 
ATOM   2792  C CB  . GLN B 2 49  ? -35.899  -38.422 19.966  1.00 39.36  ? 49  GLN B CB  1 
ATOM   2793  C CG  . GLN B 2 49  ? -35.488  -39.624 19.090  1.00 46.15  ? 49  GLN B CG  1 
ATOM   2794  C CD  . GLN B 2 49  ? -34.122  -40.213 19.441  1.00 50.19  ? 49  GLN B CD  1 
ATOM   2795  O OE1 . GLN B 2 49  ? -33.101  -39.503 19.477  1.00 43.21  ? 49  GLN B OE1 1 
ATOM   2796  N NE2 . GLN B 2 49  ? -34.098  -41.526 19.688  1.00 41.87  ? 49  GLN B NE2 1 
ATOM   2797  N N   . LEU B 2 50  ? -38.659  -38.981 17.969  1.00 42.17  ? 50  LEU B N   1 
ATOM   2798  C CA  . LEU B 2 50  ? -39.808  -39.826 17.652  1.00 44.22  ? 50  LEU B CA  1 
ATOM   2799  C C   . LEU B 2 50  ? -39.480  -41.300 17.828  1.00 43.75  ? 50  LEU B C   1 
ATOM   2800  O O   . LEU B 2 50  ? -38.401  -41.761 17.447  1.00 43.80  ? 50  LEU B O   1 
ATOM   2801  C CB  . LEU B 2 50  ? -40.284  -39.583 16.224  1.00 40.85  ? 50  LEU B CB  1 
ATOM   2802  C CG  . LEU B 2 50  ? -40.299  -38.166 15.675  1.00 46.89  ? 50  LEU B CG  1 
ATOM   2803  C CD1 . LEU B 2 50  ? -41.098  -38.148 14.384  1.00 51.17  ? 50  LEU B CD1 1 
ATOM   2804  C CD2 . LEU B 2 50  ? -40.881  -37.152 16.687  1.00 49.38  ? 50  LEU B CD2 1 
ATOM   2805  N N   . GLU B 2 51  ? -40.441  -42.048 18.376  1.00 54.35  ? 51  GLU B N   1 
ATOM   2806  C CA  . GLU B 2 51  ? -40.240  -43.444 18.760  1.00 59.06  ? 51  GLU B CA  1 
ATOM   2807  C C   . GLU B 2 51  ? -40.773  -44.387 17.690  1.00 55.14  ? 51  GLU B C   1 
ATOM   2808  O O   . GLU B 2 51  ? -41.897  -44.210 17.201  1.00 48.56  ? 51  GLU B O   1 
ATOM   2809  C CB  . GLU B 2 51  ? -40.921  -43.739 20.098  1.00 54.75  ? 51  GLU B CB  1 
ATOM   2810  C CG  . GLU B 2 51  ? -40.717  -42.635 21.116  1.00 62.56  ? 51  GLU B CG  1 
ATOM   2811  C CD  . GLU B 2 51  ? -41.227  -42.993 22.497  1.00 77.83  ? 51  GLU B CD  1 
ATOM   2812  O OE1 . GLU B 2 51  ? -42.170  -42.312 22.967  1.00 81.36  ? 51  GLU B OE1 1 
ATOM   2813  O OE2 . GLU B 2 51  ? -40.677  -43.945 23.109  1.00 79.80  ? 51  GLU B OE2 1 
ATOM   2814  N N   . ASP B 2 52  ? -39.955  -45.373 17.320  1.00 57.90  ? 52  ASP B N   1 
ATOM   2815  C CA  . ASP B 2 52  ? -40.440  -46.503 16.533  1.00 61.75  ? 52  ASP B CA  1 
ATOM   2816  C C   . ASP B 2 52  ? -41.674  -47.105 17.202  1.00 61.50  ? 52  ASP B C   1 
ATOM   2817  O O   . ASP B 2 52  ? -41.608  -47.554 18.351  1.00 62.37  ? 52  ASP B O   1 
ATOM   2818  C CB  . ASP B 2 52  ? -39.342  -47.572 16.394  1.00 60.76  ? 52  ASP B CB  1 
ATOM   2819  C CG  . ASP B 2 52  ? -38.227  -47.164 15.444  1.00 59.75  ? 52  ASP B CG  1 
ATOM   2820  O OD1 . ASP B 2 52  ? -38.372  -46.117 14.775  1.00 59.83  ? 52  ASP B OD1 1 
ATOM   2821  O OD2 . ASP B 2 52  ? -37.213  -47.892 15.364  1.00 48.46  ? 52  ASP B OD2 1 
ATOM   2822  N N   . GLY B 2 53  ? -42.806  -47.078 16.508  1.00 53.46  ? 53  GLY B N   1 
ATOM   2823  C CA  . GLY B 2 53  ? -44.044  -47.641 17.074  1.00 52.11  ? 53  GLY B CA  1 
ATOM   2824  C C   . GLY B 2 53  ? -45.173  -46.641 17.038  1.00 56.40  ? 53  GLY B C   1 
ATOM   2825  O O   . GLY B 2 53  ? -46.284  -47.024 16.646  1.00 54.57  ? 53  GLY B O   1 
ATOM   2826  N N   . ARG B 2 54  ? -44.901  -45.402 17.440  1.00 53.04  ? 54  ARG B N   1 
ATOM   2827  C CA  . ARG B 2 54  ? -45.909  -44.365 17.354  1.00 54.38  ? 54  ARG B CA  1 
ATOM   2828  C C   . ARG B 2 54  ? -46.001  -43.868 15.906  1.00 51.11  ? 54  ARG B C   1 
ATOM   2829  O O   . ARG B 2 54  ? -45.131  -44.132 15.078  1.00 52.56  ? 54  ARG B O   1 
ATOM   2830  C CB  . ARG B 2 54  ? -45.582  -43.243 18.347  1.00 51.83  ? 54  ARG B CB  1 
ATOM   2831  N N   . THR B 2 55  ? -47.081  -43.171 15.587  1.00 51.91  ? 55  THR B N   1 
ATOM   2832  C CA  . THR B 2 55  ? -47.285  -42.632 14.251  1.00 52.78  ? 55  THR B CA  1 
ATOM   2833  C C   . THR B 2 55  ? -47.088  -41.116 14.245  1.00 52.54  ? 55  THR B C   1 
ATOM   2834  O O   . THR B 2 55  ? -46.919  -40.487 15.298  1.00 55.06  ? 55  THR B O   1 
ATOM   2835  C CB  . THR B 2 55  ? -48.679  -42.982 13.760  1.00 56.29  ? 55  THR B CB  1 
ATOM   2836  O OG1 . THR B 2 55  ? -49.589  -42.008 14.279  1.00 52.32  ? 55  THR B OG1 1 
ATOM   2837  C CG2 . THR B 2 55  ? -49.068  -44.385 14.250  1.00 54.11  ? 55  THR B CG2 1 
ATOM   2838  N N   . LEU B 2 56  ? -47.124  -40.523 13.036  1.00 49.31  ? 56  LEU B N   1 
ATOM   2839  C CA  . LEU B 2 56  ? -46.971  -39.067 12.895  1.00 51.17  ? 56  LEU B CA  1 
ATOM   2840  C C   . LEU B 2 56  ? -48.129  -38.291 13.509  1.00 55.12  ? 56  LEU B C   1 
ATOM   2841  O O   . LEU B 2 56  ? -47.955  -37.137 13.919  1.00 54.65  ? 56  LEU B O   1 
ATOM   2842  C CB  . LEU B 2 56  ? -46.827  -38.664 11.425  1.00 48.66  ? 56  LEU B CB  1 
ATOM   2843  C CG  . LEU B 2 56  ? -45.580  -39.102 10.680  1.00 54.68  ? 56  LEU B CG  1 
ATOM   2844  C CD1 . LEU B 2 56  ? -45.680  -38.679 9.204   1.00 56.95  ? 56  LEU B CD1 1 
ATOM   2845  C CD2 . LEU B 2 56  ? -44.365  -38.513 11.359  1.00 48.70  ? 56  LEU B CD2 1 
ATOM   2846  N N   . SER B 2 57  ? -49.320  -38.878 13.533  1.00 56.87  ? 57  SER B N   1 
ATOM   2847  C CA  . SER B 2 57  ? -50.511  -38.195 14.097  1.00 56.54  ? 57  SER B CA  1 
ATOM   2848  C C   . SER B 2 57  ? -50.344  -38.024 15.603  1.00 54.42  ? 57  SER B C   1 
ATOM   2849  O O   . SER B 2 57  ? -50.876  -37.050 16.147  1.00 53.69  ? 57  SER B O   1 
ATOM   2850  C CB  . SER B 2 57  ? -51.746  -38.974 13.783  1.00 52.13  ? 57  SER B CB  1 
ATOM   2851  O OG  . SER B 2 57  ? -51.818  -40.159 14.560  1.00 63.03  ? 57  SER B OG  1 
ATOM   2852  N N   . ASP B 2 58  ? -49.599  -38.922 16.235  1.00 54.85  ? 58  ASP B N   1 
ATOM   2853  C CA  . ASP B 2 58  ? -49.430  -38.909 17.706  1.00 50.46  ? 58  ASP B CA  1 
ATOM   2854  C C   . ASP B 2 58  ? -48.534  -37.750 18.122  1.00 50.35  ? 58  ASP B C   1 
ATOM   2855  O O   . ASP B 2 58  ? -48.399  -37.538 19.331  1.00 48.61  ? 58  ASP B O   1 
ATOM   2856  C CB  . ASP B 2 58  ? -48.882  -40.255 18.176  1.00 44.24  ? 58  ASP B CB  1 
ATOM   2857  C CG  . ASP B 2 58  ? -49.672  -41.458 17.694  1.00 58.17  ? 58  ASP B CG  1 
ATOM   2858  O OD1 . ASP B 2 58  ? -50.811  -41.271 17.228  1.00 57.28  ? 58  ASP B OD1 1 
ATOM   2859  O OD2 . ASP B 2 58  ? -49.142  -42.576 17.796  1.00 59.70  ? 58  ASP B OD2 1 
ATOM   2860  N N   . TYR B 2 59  ? -47.959  -37.034 17.158  1.00 49.56  ? 59  TYR B N   1 
ATOM   2861  C CA  . TYR B 2 59  ? -47.066  -35.891 17.457  1.00 46.59  ? 59  TYR B CA  1 
ATOM   2862  C C   . TYR B 2 59  ? -47.641  -34.626 16.825  1.00 54.26  ? 59  TYR B C   1 
ATOM   2863  O O   . TYR B 2 59  ? -46.908  -33.636 16.780  1.00 57.99  ? 59  TYR B O   1 
ATOM   2864  C CB  . TYR B 2 59  ? -45.658  -36.185 16.945  1.00 43.45  ? 59  TYR B CB  1 
ATOM   2865  C CG  . TYR B 2 59  ? -44.924  -37.326 17.597  1.00 42.74  ? 59  TYR B CG  1 
ATOM   2866  C CD1 . TYR B 2 59  ? -44.238  -37.145 18.783  1.00 43.83  ? 59  TYR B CD1 1 
ATOM   2867  C CD2 . TYR B 2 59  ? -44.881  -38.576 17.009  1.00 47.41  ? 59  TYR B CD2 1 
ATOM   2868  C CE1 . TYR B 2 59  ? -43.549  -38.185 19.383  1.00 48.99  ? 59  TYR B CE1 1 
ATOM   2869  C CE2 . TYR B 2 59  ? -44.198  -39.628 17.594  1.00 49.23  ? 59  TYR B CE2 1 
ATOM   2870  C CZ  . TYR B 2 59  ? -43.529  -39.430 18.786  1.00 44.19  ? 59  TYR B CZ  1 
ATOM   2871  O OH  . TYR B 2 59  ? -42.851  -40.454 19.373  1.00 46.60  ? 59  TYR B OH  1 
ATOM   2872  N N   . ASN B 2 60  ? -48.902  -34.650 16.389  1.00 56.37  ? 60  ASN B N   1 
ATOM   2873  C CA  . ASN B 2 60  ? -49.538  -33.499 15.687  1.00 55.37  ? 60  ASN B CA  1 
ATOM   2874  C C   . ASN B 2 60  ? -48.624  -33.044 14.554  1.00 55.36  ? 60  ASN B C   1 
ATOM   2875  O O   . ASN B 2 60  ? -48.486  -31.832 14.337  1.00 54.83  ? 60  ASN B O   1 
ATOM   2876  C CB  . ASN B 2 60  ? -49.954  -32.371 16.632  1.00 57.49  ? 60  ASN B CB  1 
ATOM   2877  C CG  . ASN B 2 60  ? -51.072  -31.515 16.076  1.00 71.15  ? 60  ASN B CG  1 
ATOM   2878  O OD1 . ASN B 2 60  ? -51.926  -31.999 15.339  1.00 78.92  ? 60  ASN B OD1 1 
ATOM   2879  N ND2 . ASN B 2 60  ? -51.068  -30.236 16.412  1.00 66.39  ? 60  ASN B ND2 1 
ATOM   2880  N N   . ILE B 2 61  ? -48.024  -34.004 13.862  1.00 56.61  ? 61  ILE B N   1 
ATOM   2881  C CA  . ILE B 2 61  ? -47.191  -33.679 12.708  1.00 53.62  ? 61  ILE B CA  1 
ATOM   2882  C C   . ILE B 2 61  ? -48.107  -33.551 11.503  1.00 57.41  ? 61  ILE B C   1 
ATOM   2883  O O   . ILE B 2 61  ? -48.975  -34.404 11.278  1.00 57.37  ? 61  ILE B O   1 
ATOM   2884  C CB  . ILE B 2 61  ? -46.113  -34.753 12.476  1.00 50.81  ? 61  ILE B CB  1 
ATOM   2885  C CG1 . ILE B 2 61  ? -44.894  -34.537 13.385  1.00 52.54  ? 61  ILE B CG1 1 
ATOM   2886  C CG2 . ILE B 2 61  ? -45.648  -34.729 11.048  1.00 48.86  ? 61  ILE B CG2 1 
ATOM   2887  C CD1 . ILE B 2 61  ? -44.068  -35.801 13.653  1.00 46.04  ? 61  ILE B CD1 1 
ATOM   2888  N N   . GLN B 2 62  ? -47.941  -32.479 10.737  1.00 54.49  ? 62  GLN B N   1 
ATOM   2889  C CA  . GLN B 2 62  ? -48.845  -32.231 9.632   1.00 50.37  ? 62  GLN B CA  1 
ATOM   2890  C C   . GLN B 2 62  ? -48.076  -31.633 8.459   1.00 54.71  ? 62  GLN B C   1 
ATOM   2891  O O   . GLN B 2 62  ? -46.847  -31.471 8.504   1.00 55.78  ? 62  GLN B O   1 
ATOM   2892  C CB  . GLN B 2 62  ? -50.002  -31.331 10.078  1.00 47.98  ? 62  GLN B CB  1 
ATOM   2893  C CG  . GLN B 2 62  ? -49.593  -30.081 10.800  1.00 55.65  ? 62  GLN B CG  1 
ATOM   2894  C CD  . GLN B 2 62  ? -50.635  -29.642 11.818  1.00 67.45  ? 62  GLN B CD  1 
ATOM   2895  O OE1 . GLN B 2 62  ? -51.773  -30.118 11.794  1.00 63.09  ? 62  GLN B OE1 1 
ATOM   2896  N NE2 . GLN B 2 62  ? -50.243  -28.743 12.733  1.00 70.50  ? 62  GLN B NE2 1 
ATOM   2897  N N   . LYS B 2 63  ? -48.822  -31.320 7.399   1.00 47.06  ? 63  LYS B N   1 
ATOM   2898  C CA  . LYS B 2 63  ? -48.272  -30.668 6.224   1.00 46.30  ? 63  LYS B CA  1 
ATOM   2899  C C   . LYS B 2 63  ? -47.373  -29.508 6.621   1.00 45.89  ? 63  LYS B C   1 
ATOM   2900  O O   . LYS B 2 63  ? -47.752  -28.662 7.431   1.00 48.53  ? 63  LYS B O   1 
ATOM   2901  C CB  . LYS B 2 63  ? -49.419  -30.179 5.323   1.00 52.02  ? 63  LYS B CB  1 
ATOM   2902  C CG  . LYS B 2 63  ? -49.079  -30.086 3.823   1.00 51.97  ? 63  LYS B CG  1 
ATOM   2903  C CD  . LYS B 2 63  ? -49.637  -28.819 3.182   1.00 44.31  ? 63  LYS B CD  1 
ATOM   2904  C CE  . LYS B 2 63  ? -48.977  -28.511 1.847   1.00 42.41  ? 63  LYS B CE  1 
ATOM   2905  N NZ  . LYS B 2 63  ? -47.483  -28.658 1.978   1.00 59.71  ? 63  LYS B NZ  1 
ATOM   2906  N N   . GLU B 2 64  ? -46.164  -29.492 6.058   1.00 49.32  ? 64  GLU B N   1 
ATOM   2907  C CA  . GLU B 2 64  ? -45.136  -28.453 6.188   1.00 49.97  ? 64  GLU B CA  1 
ATOM   2908  C C   . GLU B 2 64  ? -44.445  -28.466 7.533   1.00 47.40  ? 64  GLU B C   1 
ATOM   2909  O O   . GLU B 2 64  ? -43.618  -27.579 7.787   1.00 47.59  ? 64  GLU B O   1 
ATOM   2910  C CB  . GLU B 2 64  ? -45.676  -27.043 5.910   1.00 44.34  ? 64  GLU B CB  1 
ATOM   2911  C CG  . GLU B 2 64  ? -46.521  -27.037 4.676   1.00 44.58  ? 64  GLU B CG  1 
ATOM   2912  C CD  . GLU B 2 64  ? -47.054  -25.695 4.299   1.00 50.34  ? 64  GLU B CD  1 
ATOM   2913  O OE1 . GLU B 2 64  ? -46.505  -24.668 4.765   1.00 55.78  ? 64  GLU B OE1 1 
ATOM   2914  O OE2 . GLU B 2 64  ? -48.010  -25.673 3.486   1.00 50.30  ? 64  GLU B OE2 1 
ATOM   2915  N N   . SER B 2 65  ? -44.743  -29.430 8.401   1.00 43.35  ? 65  SER B N   1 
ATOM   2916  C CA  . SER B 2 65  ? -43.915  -29.622 9.576   1.00 48.35  ? 65  SER B CA  1 
ATOM   2917  C C   . SER B 2 65  ? -42.508  -30.018 9.141   1.00 43.30  ? 65  SER B C   1 
ATOM   2918  O O   . SER B 2 65  ? -42.286  -30.461 8.015   1.00 50.61  ? 65  SER B O   1 
ATOM   2919  C CB  . SER B 2 65  ? -44.507  -30.699 10.491  1.00 54.66  ? 65  SER B CB  1 
ATOM   2920  O OG  . SER B 2 65  ? -45.919  -30.606 10.585  1.00 56.85  ? 65  SER B OG  1 
ATOM   2921  N N   . THR B 2 66  ? -41.546  -29.864 10.039  1.00 37.15  ? 66  THR B N   1 
ATOM   2922  C CA  . THR B 2 66  ? -40.146  -30.066 9.694   1.00 41.83  ? 66  THR B CA  1 
ATOM   2923  C C   . THR B 2 66  ? -39.505  -31.051 10.661  1.00 41.53  ? 66  THR B C   1 
ATOM   2924  O O   . THR B 2 66  ? -39.477  -30.812 11.868  1.00 46.29  ? 66  THR B O   1 
ATOM   2925  C CB  . THR B 2 66  ? -39.380  -28.742 9.729   1.00 43.26  ? 66  THR B CB  1 
ATOM   2926  O OG1 . THR B 2 66  ? -39.997  -27.781 8.853   1.00 47.30  ? 66  THR B OG1 1 
ATOM   2927  C CG2 . THR B 2 66  ? -37.920  -28.981 9.364   1.00 41.38  ? 66  THR B CG2 1 
ATOM   2928  N N   . LEU B 2 67  ? -38.957  -32.134 10.146  1.00 39.04  ? 67  LEU B N   1 
ATOM   2929  C CA  . LEU B 2 67  ? -38.205  -33.030 11.014  1.00 39.17  ? 67  LEU B CA  1 
ATOM   2930  C C   . LEU B 2 67  ? -36.718  -32.766 10.832  1.00 40.66  ? 67  LEU B C   1 
ATOM   2931  O O   . LEU B 2 67  ? -36.278  -32.349 9.754   1.00 43.10  ? 67  LEU B O   1 
ATOM   2932  C CB  . LEU B 2 67  ? -38.524  -34.490 10.712  1.00 36.09  ? 67  LEU B CB  1 
ATOM   2933  C CG  . LEU B 2 67  ? -39.819  -35.121 11.223  1.00 35.98  ? 67  LEU B CG  1 
ATOM   2934  C CD1 . LEU B 2 67  ? -40.962  -34.172 11.172  1.00 39.59  ? 67  LEU B CD1 1 
ATOM   2935  C CD2 . LEU B 2 67  ? -40.119  -36.330 10.357  1.00 44.09  ? 67  LEU B CD2 1 
ATOM   2936  N N   . HIS B 2 68  ? -35.946  -32.976 11.901  1.00 38.20  ? 68  HIS B N   1 
ATOM   2937  C CA  . HIS B 2 68  ? -34.492  -32.805 11.867  1.00 35.90  ? 68  HIS B CA  1 
ATOM   2938  C C   . HIS B 2 68  ? -33.826  -34.159 12.043  1.00 39.59  ? 68  HIS B C   1 
ATOM   2939  O O   . HIS B 2 68  ? -33.958  -34.791 13.098  1.00 39.16  ? 68  HIS B O   1 
ATOM   2940  C CB  . HIS B 2 68  ? -33.988  -31.851 12.945  1.00 35.21  ? 68  HIS B CB  1 
ATOM   2941  C CG  . HIS B 2 68  ? -34.732  -30.572 12.993  1.00 33.65  ? 68  HIS B CG  1 
ATOM   2942  N ND1 . HIS B 2 68  ? -34.337  -29.460 12.286  1.00 40.65  ? 68  HIS B ND1 1 
ATOM   2943  C CD2 . HIS B 2 68  ? -35.880  -30.238 13.620  1.00 29.32  ? 68  HIS B CD2 1 
ATOM   2944  C CE1 . HIS B 2 68  ? -35.211  -28.493 12.482  1.00 37.87  ? 68  HIS B CE1 1 
ATOM   2945  N NE2 . HIS B 2 68  ? -36.154  -28.941 13.289  1.00 34.44  ? 68  HIS B NE2 1 
ATOM   2946  N N   . LEU B 2 69  ? -33.132  -34.599 10.991  1.00 41.96  ? 69  LEU B N   1 
ATOM   2947  C CA  . LEU B 2 69  ? -32.454  -35.919 10.992  1.00 45.97  ? 69  LEU B CA  1 
ATOM   2948  C C   . LEU B 2 69  ? -31.114  -35.806 11.705  1.00 44.52  ? 69  LEU B C   1 
ATOM   2949  O O   . LEU B 2 69  ? -30.392  -34.827 11.464  1.00 48.29  ? 69  LEU B O   1 
ATOM   2950  C CB  . LEU B 2 69  ? -32.258  -36.378 9.544   1.00 38.59  ? 69  LEU B CB  1 
ATOM   2951  C CG  . LEU B 2 69  ? -31.445  -37.648 9.319   1.00 39.56  ? 69  LEU B CG  1 
ATOM   2952  C CD1 . LEU B 2 69  ? -32.187  -38.860 9.841   1.00 38.97  ? 69  LEU B CD1 1 
ATOM   2953  C CD2 . LEU B 2 69  ? -31.136  -37.818 7.844   1.00 41.83  ? 69  LEU B CD2 1 
ATOM   2954  N N   . VAL B 2 70  ? -30.804  -36.807 12.519  1.00 41.33  ? 70  VAL B N   1 
ATOM   2955  C CA  . VAL B 2 70  ? -29.541  -36.800 13.293  1.00 45.12  ? 70  VAL B CA  1 
ATOM   2956  C C   . VAL B 2 70  ? -29.048  -38.241 13.464  1.00 43.47  ? 70  VAL B C   1 
ATOM   2957  O O   . VAL B 2 70  ? -29.873  -39.143 13.464  1.00 44.94  ? 70  VAL B O   1 
ATOM   2958  C CB  . VAL B 2 70  ? -29.790  -36.038 14.610  1.00 49.11  ? 70  VAL B CB  1 
ATOM   2959  C CG1 . VAL B 2 70  ? -29.252  -36.726 15.839  1.00 53.89  ? 70  VAL B CG1 1 
ATOM   2960  C CG2 . VAL B 2 70  ? -29.305  -34.607 14.552  1.00 41.39  ? 70  VAL B CG2 1 
ATOM   2961  N N   . LEU B 2 71  ? -27.737  -38.456 13.469  1.00 42.04  ? 71  LEU B N   1 
ATOM   2962  C CA  . LEU B 2 71  ? -27.129  -39.757 13.739  1.00 50.89  ? 71  LEU B CA  1 
ATOM   2963  C C   . LEU B 2 71  ? -26.647  -39.818 15.199  1.00 51.56  ? 71  LEU B C   1 
ATOM   2964  O O   . LEU B 2 71  ? -27.000  -38.967 16.025  1.00 47.02  ? 71  LEU B O   1 
ATOM   2965  C CB  . LEU B 2 71  ? -25.988  -40.036 12.753  1.00 47.92  ? 71  LEU B CB  1 
ATOM   2966  C CG  . LEU B 2 71  ? -26.333  -39.890 11.266  1.00 46.85  ? 71  LEU B CG  1 
ATOM   2967  C CD1 . LEU B 2 71  ? -25.119  -40.054 10.390  1.00 47.02  ? 71  LEU B CD1 1 
ATOM   2968  C CD2 . LEU B 2 71  ? -27.415  -40.843 10.828  1.00 40.57  ? 71  LEU B CD2 1 
ATOM   2969  N N   . ARG B 2 72  ? -25.833  -40.831 15.536  1.00 48.86  ? 72  ARG B N   1 
ATOM   2970  C CA  . ARG B 2 72  ? -25.355  -41.022 16.905  1.00 45.09  ? 72  ARG B CA  1 
ATOM   2971  C C   . ARG B 2 72  ? -23.846  -40.838 17.003  1.00 48.89  ? 72  ARG B C   1 
ATOM   2972  O O   . ARG B 2 72  ? -23.101  -41.197 16.091  1.00 57.11  ? 72  ARG B O   1 
ATOM   2973  C CB  . ARG B 2 72  ? -25.712  -42.413 17.442  1.00 42.34  ? 72  ARG B CB  1 
ATOM   2974  C CG  . ARG B 2 72  ? -27.193  -42.727 17.450  1.00 43.93  ? 72  ARG B CG  1 
ATOM   2975  C CD  . ARG B 2 72  ? -27.552  -43.848 18.425  1.00 46.90  ? 72  ARG B CD  1 
ATOM   2976  N NE  . ARG B 2 72  ? -29.004  -44.021 18.573  1.00 47.30  ? 72  ARG B NE  1 
ATOM   2977  C CZ  . ARG B 2 72  ? -29.777  -44.615 17.670  1.00 44.09  ? 72  ARG B CZ  1 
ATOM   2978  N NH1 . ARG B 2 72  ? -29.233  -45.096 16.564  1.00 50.69  ? 72  ARG B NH1 1 
ATOM   2979  N NH2 . ARG B 2 72  ? -31.083  -44.725 17.864  1.00 39.51  ? 72  ARG B NH2 1 
ATOM   2980  N N   . LEU B 2 73  ? -23.400  -40.274 18.115  1.00 49.54  ? 73  LEU B N   1 
ATOM   2981  C CA  . LEU B 2 73  ? -22.004  -40.332 18.544  1.00 48.52  ? 73  LEU B CA  1 
ATOM   2982  C C   . LEU B 2 73  ? -22.065  -41.035 19.893  1.00 55.45  ? 73  LEU B C   1 
ATOM   2983  O O   . LEU B 2 73  ? -22.450  -40.431 20.905  1.00 53.34  ? 73  LEU B O   1 
ATOM   2984  C CB  . LEU B 2 73  ? -21.358  -38.951 18.642  1.00 46.82  ? 73  LEU B CB  1 
ATOM   2985  C CG  . LEU B 2 73  ? -21.084  -38.176 17.348  1.00 45.54  ? 73  LEU B CG  1 
ATOM   2986  C CD1 . LEU B 2 73  ? -20.326  -36.910 17.644  1.00 47.11  ? 73  LEU B CD1 1 
ATOM   2987  C CD2 . LEU B 2 73  ? -20.337  -39.009 16.335  1.00 47.04  ? 73  LEU B CD2 1 
ATOM   2988  N N   . ARG B 2 74  ? -21.744  -42.325 19.849  1.00 60.07  ? 74  ARG B N   1 
ATOM   2989  C CA  . ARG B 2 74  ? -21.888  -43.171 21.050  1.00 53.14  ? 74  ARG B CA  1 
ATOM   2990  C C   . ARG B 2 74  ? -20.682  -43.038 21.974  1.00 60.31  ? 74  ARG B C   1 
ATOM   2991  O O   . ARG B 2 74  ? -19.602  -42.660 21.504  1.00 61.13  ? 74  ARG B O   1 
ATOM   2992  C CB  . ARG B 2 74  ? -22.170  -44.604 20.596  1.00 51.64  ? 74  ARG B CB  1 
ATOM   2993  C CG  . ARG B 2 74  ? -23.406  -44.741 19.722  1.00 52.36  ? 74  ARG B CG  1 
ATOM   2994  C CD  . ARG B 2 74  ? -23.794  -46.187 19.500  1.00 44.28  ? 74  ARG B CD  1 
ATOM   2995  N NE  . ARG B 2 74  ? -24.972  -46.536 20.277  1.00 52.96  ? 74  ARG B NE  1 
ATOM   2996  C CZ  . ARG B 2 74  ? -26.104  -46.998 19.767  1.00 53.30  ? 74  ARG B CZ  1 
ATOM   2997  N NH1 . ARG B 2 74  ? -26.222  -47.175 18.464  1.00 48.72  ? 74  ARG B NH1 1 
ATOM   2998  N NH2 . ARG B 2 74  ? -27.119  -47.282 20.562  1.00 44.41  ? 74  ARG B NH2 1 
ATOM   2999  N N   . GLY B 2 75  ? -20.884  -43.286 23.266  1.00 63.94  ? 75  GLY B N   1 
ATOM   3000  C CA  . GLY B 2 75  ? -19.800  -43.162 24.254  1.00 64.70  ? 75  GLY B CA  1 
ATOM   3001  C C   . GLY B 2 75  ? -20.243  -43.590 25.639  1.00 65.73  ? 75  GLY B C   1 
ATOM   3002  O O   . GLY B 2 75  ? -19.522  -44.399 26.237  1.00 64.90  ? 75  GLY B O   1 
ATOM   3003  N N   . THR C 1 4   ? -93.206  -7.139  39.598  1.00 69.32  ? 211 THR C N   1 
ATOM   3004  C CA  . THR C 1 4   ? -92.401  -7.237  38.354  1.00 67.88  ? 211 THR C CA  1 
ATOM   3005  C C   . THR C 1 4   ? -93.332  -7.035  37.160  1.00 72.90  ? 211 THR C C   1 
ATOM   3006  O O   . THR C 1 4   ? -93.213  -5.992  36.500  1.00 73.31  ? 211 THR C O   1 
ATOM   3007  C CB  . THR C 1 4   ? -91.615  -8.558  38.309  1.00 74.48  ? 211 THR C CB  1 
ATOM   3008  O OG1 . THR C 1 4   ? -91.424  -8.959  36.953  1.00 77.00  ? 211 THR C OG1 1 
ATOM   3009  C CG2 . THR C 1 4   ? -92.274  -9.688  39.071  1.00 70.95  ? 211 THR C CG2 1 
ATOM   3010  N N   . GLY C 1 5   ? -94.243  -7.976  36.927  1.00 72.88  ? 212 GLY C N   1 
ATOM   3011  C CA  . GLY C 1 5   ? -95.137  -7.918  35.757  1.00 68.12  ? 212 GLY C CA  1 
ATOM   3012  C C   . GLY C 1 5   ? -94.683  -8.903  34.707  1.00 63.95  ? 212 GLY C C   1 
ATOM   3013  O O   . GLY C 1 5   ? -95.456  -9.151  33.770  1.00 61.60  ? 212 GLY C O   1 
ATOM   3014  N N   . TYR C 1 6   ? -93.485  -9.461  34.874  1.00 62.78  ? 213 TYR C N   1 
ATOM   3015  C CA  . TYR C 1 6   ? -92.911  -10.362 33.847  1.00 69.68  ? 213 TYR C CA  1 
ATOM   3016  C C   . TYR C 1 6   ? -92.683  -11.759 34.421  1.00 69.81  ? 213 TYR C C   1 
ATOM   3017  O O   . TYR C 1 6   ? -92.366  -11.878 35.610  1.00 73.79  ? 213 TYR C O   1 
ATOM   3018  C CB  . TYR C 1 6   ? -91.589  -9.801  33.318  1.00 66.15  ? 213 TYR C CB  1 
ATOM   3019  C CG  . TYR C 1 6   ? -91.466  -8.301  33.240  1.00 63.28  ? 213 TYR C CG  1 
ATOM   3020  C CD1 . TYR C 1 6   ? -92.164  -7.570  32.295  1.00 61.41  ? 213 TYR C CD1 1 
ATOM   3021  C CD2 . TYR C 1 6   ? -90.615  -7.614  34.088  1.00 65.05  ? 213 TYR C CD2 1 
ATOM   3022  C CE1 . TYR C 1 6   ? -92.043  -6.194  32.212  1.00 59.09  ? 213 TYR C CE1 1 
ATOM   3023  C CE2 . TYR C 1 6   ? -90.483  -6.239  34.021  1.00 59.58  ? 213 TYR C CE2 1 
ATOM   3024  C CZ  . TYR C 1 6   ? -91.199  -5.526  33.079  1.00 61.11  ? 213 TYR C CZ  1 
ATOM   3025  O OH  . TYR C 1 6   ? -91.067  -4.171  33.006  1.00 68.37  ? 213 TYR C OH  1 
ATOM   3026  N N   . VAL C 1 7   ? -92.828  -12.787 33.584  1.00 68.30  ? 214 VAL C N   1 
ATOM   3027  C CA  . VAL C 1 7   ? -92.590  -14.153 34.025  1.00 67.05  ? 214 VAL C CA  1 
ATOM   3028  C C   . VAL C 1 7   ? -91.163  -14.553 33.681  1.00 68.34  ? 214 VAL C C   1 
ATOM   3029  O O   . VAL C 1 7   ? -90.478  -13.853 32.928  1.00 72.35  ? 214 VAL C O   1 
ATOM   3030  C CB  . VAL C 1 7   ? -93.616  -15.102 33.391  1.00 69.77  ? 214 VAL C CB  1 
ATOM   3031  C CG1 . VAL C 1 7   ? -93.689  -16.387 34.169  1.00 75.01  ? 214 VAL C CG1 1 
ATOM   3032  C CG2 . VAL C 1 7   ? -94.974  -14.432 33.377  1.00 72.30  ? 214 VAL C CG2 1 
ATOM   3033  N N   . GLY C 1 8   ? -90.701  -15.663 34.248  1.00 65.07  ? 215 GLY C N   1 
ATOM   3034  C CA  . GLY C 1 8   ? -89.426  -16.256 33.917  1.00 63.21  ? 215 GLY C CA  1 
ATOM   3035  C C   . GLY C 1 8   ? -89.569  -17.481 33.034  1.00 66.65  ? 215 GLY C C   1 
ATOM   3036  O O   . GLY C 1 8   ? -90.599  -17.695 32.383  1.00 61.51  ? 215 GLY C O   1 
ATOM   3037  N N   . LEU C 1 9   ? -88.517  -18.307 33.024  1.00 63.55  ? 216 LEU C N   1 
ATOM   3038  C CA  . LEU C 1 9   ? -88.413  -19.408 32.074  1.00 67.51  ? 216 LEU C CA  1 
ATOM   3039  C C   . LEU C 1 9   ? -87.701  -20.578 32.736  1.00 68.90  ? 216 LEU C C   1 
ATOM   3040  O O   . LEU C 1 9   ? -86.723  -20.392 33.459  1.00 72.83  ? 216 LEU C O   1 
ATOM   3041  C CB  . LEU C 1 9   ? -87.669  -18.979 30.795  1.00 70.84  ? 216 LEU C CB  1 
ATOM   3042  N N   . LYS C 1 10  ? -88.184  -21.783 32.470  1.00 71.06  ? 217 LYS C N   1 
ATOM   3043  C CA  . LYS C 1 10  ? -87.796  -22.945 33.256  1.00 68.04  ? 217 LYS C CA  1 
ATOM   3044  C C   . LYS C 1 10  ? -86.461  -23.499 32.776  1.00 70.04  ? 217 LYS C C   1 
ATOM   3045  O O   . LYS C 1 10  ? -86.301  -23.820 31.597  1.00 77.19  ? 217 LYS C O   1 
ATOM   3046  C CB  . LYS C 1 10  ? -88.888  -24.018 33.172  1.00 71.16  ? 217 LYS C CB  1 
ATOM   3047  N N   . ASN C 1 11  ? -85.505  -23.623 33.688  1.00 68.96  ? 218 ASN C N   1 
ATOM   3048  C CA  . ASN C 1 11  ? -84.249  -24.268 33.338  1.00 69.01  ? 218 ASN C CA  1 
ATOM   3049  C C   . ASN C 1 11  ? -84.516  -25.725 32.983  1.00 72.51  ? 218 ASN C C   1 
ATOM   3050  O O   . ASN C 1 11  ? -85.140  -26.446 33.762  1.00 82.51  ? 218 ASN C O   1 
ATOM   3051  C CB  . ASN C 1 11  ? -83.265  -24.174 34.502  1.00 66.83  ? 218 ASN C CB  1 
ATOM   3052  C CG  . ASN C 1 11  ? -81.868  -24.680 34.146  1.00 69.62  ? 218 ASN C CG  1 
ATOM   3053  O OD1 . ASN C 1 11  ? -81.643  -25.281 33.091  1.00 62.10  ? 218 ASN C OD1 1 
ATOM   3054  N ND2 . ASN C 1 11  ? -80.918  -24.430 35.039  1.00 72.54  ? 218 ASN C ND2 1 
ATOM   3055  N N   . GLN C 1 12  ? -84.030  -26.167 31.822  1.00 72.98  ? 219 GLN C N   1 
ATOM   3056  C CA  . GLN C 1 12  ? -84.172  -27.587 31.417  1.00 64.72  ? 219 GLN C CA  1 
ATOM   3057  C C   . GLN C 1 12  ? -82.994  -28.393 31.953  1.00 70.17  ? 219 GLN C C   1 
ATOM   3058  O O   . GLN C 1 12  ? -82.926  -29.589 31.641  1.00 81.16  ? 219 GLN C O   1 
ATOM   3059  C CB  . GLN C 1 12  ? -84.132  -27.707 29.899  1.00 66.71  ? 219 GLN C CB  1 
ATOM   3060  C CG  . GLN C 1 12  ? -85.470  -27.550 29.200  1.00 66.56  ? 219 GLN C CG  1 
ATOM   3061  C CD  . GLN C 1 12  ? -85.320  -27.911 27.744  1.00 73.43  ? 219 GLN C CD  1 
ATOM   3062  O OE1 . GLN C 1 12  ? -85.455  -29.066 27.351  1.00 80.18  ? 219 GLN C OE1 1 
ATOM   3063  N NE2 . GLN C 1 12  ? -85.014  -26.921 26.926  1.00 75.10  ? 219 GLN C NE2 1 
ATOM   3064  N N   . GLY C 1 13  ? -82.094  -27.762 32.705  1.00 67.29  ? 220 GLY C N   1 
ATOM   3065  C CA  . GLY C 1 13  ? -80.896  -28.433 33.242  1.00 66.82  ? 220 GLY C CA  1 
ATOM   3066  C C   . GLY C 1 13  ? -79.696  -27.510 33.252  1.00 66.03  ? 220 GLY C C   1 
ATOM   3067  O O   . GLY C 1 13  ? -79.090  -27.354 34.322  1.00 61.45  ? 220 GLY C O   1 
ATOM   3068  N N   . ALA C 1 14  ? -79.381  -26.913 32.103  1.00 74.78  ? 221 ALA C N   1 
ATOM   3069  C CA  . ALA C 1 14  ? -78.252  -25.960 31.997  1.00 72.31  ? 221 ALA C CA  1 
ATOM   3070  C C   . ALA C 1 14  ? -78.598  -24.843 31.018  1.00 66.12  ? 221 ALA C C   1 
ATOM   3071  O O   . ALA C 1 14  ? -77.697  -24.070 30.707  1.00 69.74  ? 221 ALA C O   1 
ATOM   3072  C CB  . ALA C 1 14  ? -77.016  -26.681 31.556  1.00 69.96  ? 221 ALA C CB  1 
ATOM   3073  N N   . THR C 1 15  ? -79.867  -24.719 30.628  1.00 65.73  ? 222 THR C N   1 
ATOM   3074  C CA  . THR C 1 15  ? -80.322  -23.632 29.724  1.00 56.85  ? 222 THR C CA  1 
ATOM   3075  C C   . THR C 1 15  ? -80.274  -22.284 30.445  1.00 62.67  ? 222 THR C C   1 
ATOM   3076  O O   . THR C 1 15  ? -81.136  -21.456 30.166  1.00 63.44  ? 222 THR C O   1 
ATOM   3077  C CB  . THR C 1 15  ? -81.719  -23.941 29.178  1.00 67.04  ? 222 THR C CB  1 
ATOM   3078  O OG1 . THR C 1 15  ? -82.642  -24.016 30.263  1.00 70.28  ? 222 THR C OG1 1 
ATOM   3079  C CG2 . THR C 1 15  ? -81.754  -25.228 28.385  1.00 68.41  ? 222 THR C CG2 1 
ATOM   3080  N N   . CYS C 1 16  ? -79.317  -22.072 31.345  1.00 61.86  ? 223 CYS C N   1 
ATOM   3081  C CA  . CYS C 1 16  ? -79.164  -20.742 31.979  1.00 59.89  ? 223 CYS C CA  1 
ATOM   3082  C C   . CYS C 1 16  ? -78.824  -19.746 30.879  1.00 70.41  ? 223 CYS C C   1 
ATOM   3083  O O   . CYS C 1 16  ? -79.464  -18.688 30.829  1.00 65.94  ? 223 CYS C O   1 
ATOM   3084  C CB  . CYS C 1 16  ? -78.010  -20.713 32.972  1.00 64.63  ? 223 CYS C CB  1 
ATOM   3085  S SG  . CYS C 1 16  ? -77.399  -22.331 33.493  1.00 67.44  ? 223 CYS C SG  1 
ATOM   3086  N N   . TYR C 1 17  ? -77.847  -20.087 30.038  1.00 63.93  ? 224 TYR C N   1 
ATOM   3087  C CA  . TYR C 1 17  ? -77.392  -19.195 28.948  1.00 56.67  ? 224 TYR C CA  1 
ATOM   3088  C C   . TYR C 1 17  ? -78.566  -18.824 28.055  1.00 57.77  ? 224 TYR C C   1 
ATOM   3089  O O   . TYR C 1 17  ? -78.708  -17.649 27.719  1.00 60.52  ? 224 TYR C O   1 
ATOM   3090  C CB  . TYR C 1 17  ? -76.283  -19.898 28.160  1.00 58.66  ? 224 TYR C CB  1 
ATOM   3091  C CG  . TYR C 1 17  ? -76.669  -21.171 27.454  1.00 61.88  ? 224 TYR C CG  1 
ATOM   3092  C CD1 . TYR C 1 17  ? -76.796  -22.362 28.145  1.00 64.55  ? 224 TYR C CD1 1 
ATOM   3093  C CD2 . TYR C 1 17  ? -76.905  -21.188 26.091  1.00 56.90  ? 224 TYR C CD2 1 
ATOM   3094  C CE1 . TYR C 1 17  ? -77.163  -23.532 27.507  1.00 67.84  ? 224 TYR C CE1 1 
ATOM   3095  C CE2 . TYR C 1 17  ? -77.280  -22.347 25.436  1.00 63.84  ? 224 TYR C CE2 1 
ATOM   3096  C CZ  . TYR C 1 17  ? -77.407  -23.523 26.149  1.00 70.46  ? 224 TYR C CZ  1 
ATOM   3097  O OH  . TYR C 1 17  ? -77.761  -24.679 25.524  1.00 74.43  ? 224 TYR C OH  1 
ATOM   3098  N N   . MET C 1 18  ? -79.379  -19.807 27.697  1.00 57.71  ? 225 MET C N   1 
ATOM   3099  C CA  . MET C 1 18  ? -80.492  -19.574 26.759  1.00 52.38  ? 225 MET C CA  1 
ATOM   3100  C C   . MET C 1 18  ? -81.509  -18.672 27.423  1.00 56.86  ? 225 MET C C   1 
ATOM   3101  O O   . MET C 1 18  ? -81.967  -17.761 26.763  1.00 62.23  ? 225 MET C O   1 
ATOM   3102  C CB  . MET C 1 18  ? -81.156  -20.906 26.416  1.00 59.03  ? 225 MET C CB  1 
ATOM   3103  C CG  . MET C 1 18  ? -82.288  -20.793 25.422  1.00 63.95  ? 225 MET C CG  1 
ATOM   3104  S SD  . MET C 1 18  ? -82.620  -22.378 24.645  1.00 63.99  ? 225 MET C SD  1 
ATOM   3105  C CE  . MET C 1 18  ? -80.964  -23.060 24.632  1.00 61.48  ? 225 MET C CE  1 
ATOM   3106  N N   . ASN C 1 19  ? -81.807  -18.910 28.691  1.00 56.95  ? 226 ASN C N   1 
ATOM   3107  C CA  . ASN C 1 19  ? -82.883  -18.133 29.349  1.00 56.32  ? 226 ASN C CA  1 
ATOM   3108  C C   . ASN C 1 19  ? -82.470  -16.665 29.384  1.00 58.71  ? 226 ASN C C   1 
ATOM   3109  O O   . ASN C 1 19  ? -83.281  -15.829 29.001  1.00 63.94  ? 226 ASN C O   1 
ATOM   3110  C CB  . ASN C 1 19  ? -83.250  -18.732 30.707  1.00 66.16  ? 226 ASN C CB  1 
ATOM   3111  C CG  . ASN C 1 19  ? -83.979  -20.054 30.598  1.00 66.26  ? 226 ASN C CG  1 
ATOM   3112  O OD1 . ASN C 1 19  ? -84.549  -20.377 29.561  1.00 61.05  ? 226 ASN C OD1 1 
ATOM   3113  N ND2 . ASN C 1 19  ? -83.956  -20.834 31.663  1.00 66.58  ? 226 ASN C ND2 1 
ATOM   3114  N N   . SER C 1 20  ? -81.235  -16.380 29.767  1.00 56.28  ? 227 SER C N   1 
ATOM   3115  C CA  . SER C 1 20  ? -80.729  -14.989 29.811  1.00 55.93  ? 227 SER C CA  1 
ATOM   3116  C C   . SER C 1 20  ? -80.863  -14.324 28.439  1.00 61.40  ? 227 SER C C   1 
ATOM   3117  O O   . SER C 1 20  ? -81.413  -13.223 28.380  1.00 60.31  ? 227 SER C O   1 
ATOM   3118  C CB  . SER C 1 20  ? -79.314  -14.980 30.299  1.00 61.30  ? 227 SER C CB  1 
ATOM   3119  O OG  . SER C 1 20  ? -79.215  -15.591 31.573  1.00 66.92  ? 227 SER C OG  1 
ATOM   3120  N N   . LEU C 1 21  ? -80.380  -14.975 27.382  1.00 30.00  ? 228 LEU C N   1 
ATOM   3121  C CA  . LEU C 1 21  ? -80.465  -14.428 26.006  1.00 30.00  ? 228 LEU C CA  1 
ATOM   3122  C C   . LEU C 1 21  ? -81.925  -14.301 25.608  1.00 30.00  ? 228 LEU C C   1 
ATOM   3123  O O   . LEU C 1 21  ? -82.292  -13.265 25.069  1.00 30.00  ? 228 LEU C O   1 
ATOM   3124  C CB  . LEU C 1 21  ? -79.761  -15.400 25.061  1.00 30.00  ? 228 LEU C CB  1 
ATOM   3125  C CG  . LEU C 1 21  ? -79.001  -14.797 23.883  1.00 30.00  ? 228 LEU C CG  1 
ATOM   3126  C CD1 . LEU C 1 21  ? -79.643  -15.211 22.573  1.00 30.00  ? 228 LEU C CD1 1 
ATOM   3127  C CD2 . LEU C 1 21  ? -78.896  -13.284 23.986  1.00 30.00  ? 228 LEU C CD2 1 
ATOM   3128  N N   . LEU C 1 22  ? -82.707  -15.345 25.843  1.00 54.13  ? 229 LEU C N   1 
ATOM   3129  C CA  . LEU C 1 22  ? -84.126  -15.324 25.439  1.00 56.27  ? 229 LEU C CA  1 
ATOM   3130  C C   . LEU C 1 22  ? -84.795  -14.118 26.080  1.00 57.42  ? 229 LEU C C   1 
ATOM   3131  O O   . LEU C 1 22  ? -85.645  -13.530 25.416  1.00 58.11  ? 229 LEU C O   1 
ATOM   3132  C CB  . LEU C 1 22  ? -84.796  -16.619 25.893  1.00 51.10  ? 229 LEU C CB  1 
ATOM   3133  C CG  . LEU C 1 22  ? -84.846  -17.737 24.861  1.00 53.14  ? 229 LEU C CG  1 
ATOM   3134  C CD1 . LEU C 1 22  ? -85.507  -18.964 25.459  1.00 60.12  ? 229 LEU C CD1 1 
ATOM   3135  C CD2 . LEU C 1 22  ? -85.599  -17.279 23.628  1.00 54.13  ? 229 LEU C CD2 1 
ATOM   3136  N N   . GLN C 1 23  ? -84.430  -13.765 27.312  1.00 51.29  ? 230 GLN C N   1 
ATOM   3137  C CA  . GLN C 1 23  ? -85.144  -12.634 27.867  1.00 54.02  ? 230 GLN C CA  1 
ATOM   3138  C C   . GLN C 1 23  ? -84.630  -11.335 27.279  1.00 63.46  ? 230 GLN C C   1 
ATOM   3139  O O   . GLN C 1 23  ? -85.417  -10.411 27.018  1.00 62.57  ? 230 GLN C O   1 
ATOM   3140  C CB  . GLN C 1 23  ? -85.023  -12.635 29.381  1.00 59.31  ? 230 GLN C CB  1 
ATOM   3141  C CG  . GLN C 1 23  ? -85.693  -13.831 30.031  1.00 62.62  ? 230 GLN C CG  1 
ATOM   3142  C CD  . GLN C 1 23  ? -87.117  -13.541 30.471  1.00 69.50  ? 230 GLN C CD  1 
ATOM   3143  O OE1 . GLN C 1 23  ? -87.789  -12.659 29.912  1.00 68.82  ? 230 GLN C OE1 1 
ATOM   3144  N NE2 . GLN C 1 23  ? -87.595  -14.290 31.468  1.00 65.99  ? 230 GLN C NE2 1 
ATOM   3145  N N   . THR C 1 24  ? -83.322  -11.258 27.064  1.00 64.46  ? 231 THR C N   1 
ATOM   3146  C CA  . THR C 1 24  ? -82.721  -10.053 26.448  1.00 57.39  ? 231 THR C CA  1 
ATOM   3147  C C   . THR C 1 24  ? -83.398  -9.798  25.103  1.00 54.31  ? 231 THR C C   1 
ATOM   3148  O O   . THR C 1 24  ? -83.795  -8.654  24.869  1.00 60.66  ? 231 THR C O   1 
ATOM   3149  C CB  . THR C 1 24  ? -81.203  -10.211 26.327  1.00 59.64  ? 231 THR C CB  1 
ATOM   3150  O OG1 . THR C 1 24  ? -80.682  -10.536 27.614  1.00 59.91  ? 231 THR C OG1 1 
ATOM   3151  C CG2 . THR C 1 24  ? -80.527  -8.969  25.797  1.00 55.47  ? 231 THR C CG2 1 
ATOM   3152  N N   . LEU C 1 25  ? -83.565  -10.822 24.282  1.00 52.66  ? 232 LEU C N   1 
ATOM   3153  C CA  . LEU C 1 25  ? -84.116  -10.611 22.923  1.00 55.20  ? 232 LEU C CA  1 
ATOM   3154  C C   . LEU C 1 25  ? -85.634  -10.435 22.968  1.00 59.30  ? 232 LEU C C   1 
ATOM   3155  O O   . LEU C 1 25  ? -86.168  -9.810  22.046  1.00 58.55  ? 232 LEU C O   1 
ATOM   3156  C CB  . LEU C 1 25  ? -83.706  -11.804 22.064  1.00 55.80  ? 232 LEU C CB  1 
ATOM   3157  C CG  . LEU C 1 25  ? -82.205  -11.983 21.860  1.00 65.29  ? 232 LEU C CG  1 
ATOM   3158  C CD1 . LEU C 1 25  ? -81.949  -13.010 20.778  1.00 53.13  ? 232 LEU C CD1 1 
ATOM   3159  C CD2 . LEU C 1 25  ? -81.529  -10.666 21.514  1.00 50.74  ? 232 LEU C CD2 1 
ATOM   3160  N N   . PHE C 1 26  ? -86.303  -10.970 23.986  1.00 57.98  ? 233 PHE C N   1 
ATOM   3161  C CA  . PHE C 1 26  ? -87.739  -10.749 24.134  1.00 61.20  ? 233 PHE C CA  1 
ATOM   3162  C C   . PHE C 1 26  ? -88.028  -9.283  24.413  1.00 59.70  ? 233 PHE C C   1 
ATOM   3163  O O   . PHE C 1 26  ? -89.013  -8.724  23.917  1.00 57.35  ? 233 PHE C O   1 
ATOM   3164  C CB  . PHE C 1 26  ? -88.295  -11.631 25.259  1.00 63.55  ? 233 PHE C CB  1 
ATOM   3165  C CG  . PHE C 1 26  ? -89.739  -11.329 25.636  1.00 66.12  ? 233 PHE C CG  1 
ATOM   3166  C CD1 . PHE C 1 26  ? -90.785  -11.658 24.782  1.00 67.35  ? 233 PHE C CD1 1 
ATOM   3167  C CD2 . PHE C 1 26  ? -90.043  -10.729 26.853  1.00 63.92  ? 233 PHE C CD2 1 
ATOM   3168  C CE1 . PHE C 1 26  ? -92.098  -11.385 25.130  1.00 66.54  ? 233 PHE C CE1 1 
ATOM   3169  C CE2 . PHE C 1 26  ? -91.354  -10.452 27.198  1.00 59.54  ? 233 PHE C CE2 1 
ATOM   3170  C CZ  . PHE C 1 26  ? -92.378  -10.777 26.337  1.00 63.08  ? 233 PHE C CZ  1 
ATOM   3171  N N   . PHE C 1 27  ? -87.147  -8.675  25.200  1.00 61.67  ? 234 PHE C N   1 
ATOM   3172  C CA  . PHE C 1 27  ? -87.335  -7.259  25.592  1.00 62.32  ? 234 PHE C CA  1 
ATOM   3173  C C   . PHE C 1 27  ? -86.800  -6.346  24.495  1.00 63.24  ? 234 PHE C C   1 
ATOM   3174  O O   . PHE C 1 27  ? -86.903  -5.142  24.669  1.00 64.80  ? 234 PHE C O   1 
ATOM   3175  C CB  . PHE C 1 27  ? -86.756  -7.047  26.987  1.00 65.01  ? 234 PHE C CB  1 
ATOM   3176  C CG  . PHE C 1 27  ? -87.625  -7.661  28.052  1.00 66.08  ? 234 PHE C CG  1 
ATOM   3177  C CD1 . PHE C 1 27  ? -88.979  -7.375  28.105  1.00 65.55  ? 234 PHE C CD1 1 
ATOM   3178  C CD2 . PHE C 1 27  ? -87.107  -8.554  28.971  1.00 61.51  ? 234 PHE C CD2 1 
ATOM   3179  C CE1 . PHE C 1 27  ? -89.786  -7.936  29.081  1.00 67.99  ? 234 PHE C CE1 1 
ATOM   3180  C CE2 . PHE C 1 27  ? -87.918  -9.127  29.934  1.00 66.81  ? 234 PHE C CE2 1 
ATOM   3181  C CZ  . PHE C 1 27  ? -89.254  -8.817  29.991  1.00 66.58  ? 234 PHE C CZ  1 
ATOM   3182  N N   . THR C 1 28  ? -86.203  -6.901  23.444  1.00 57.47  ? 235 THR C N   1 
ATOM   3183  C CA  . THR C 1 28  ? -85.867  -6.083  22.260  1.00 52.12  ? 235 THR C CA  1 
ATOM   3184  C C   . THR C 1 28  ? -87.204  -6.077  21.539  1.00 54.83  ? 235 THR C C   1 
ATOM   3185  O O   . THR C 1 28  ? -87.402  -6.928  20.680  1.00 56.74  ? 235 THR C O   1 
ATOM   3186  C CB  . THR C 1 28  ? -84.680  -6.677  21.501  1.00 55.49  ? 235 THR C CB  1 
ATOM   3187  O OG1 . THR C 1 28  ? -83.644  -6.961  22.440  1.00 61.68  ? 235 THR C OG1 1 
ATOM   3188  C CG2 . THR C 1 28  ? -84.143  -5.753  20.432  1.00 55.99  ? 235 THR C CG2 1 
ATOM   3189  N N   . ASN C 1 29  ? -88.115  -5.206  21.948  1.00 56.87  ? 236 ASN C N   1 
ATOM   3190  C CA  . ASN C 1 29  ? -89.512  -5.234  21.448  1.00 58.97  ? 236 ASN C CA  1 
ATOM   3191  C C   . ASN C 1 29  ? -89.589  -5.275  19.920  1.00 60.20  ? 236 ASN C C   1 
ATOM   3192  O O   . ASN C 1 29  ? -90.388  -6.061  19.416  1.00 61.62  ? 236 ASN C O   1 
ATOM   3193  C CB  . ASN C 1 29  ? -90.299  -4.068  22.045  1.00 60.92  ? 236 ASN C CB  1 
ATOM   3194  C CG  . ASN C 1 29  ? -90.586  -4.182  23.526  1.00 63.66  ? 236 ASN C CG  1 
ATOM   3195  O OD1 . ASN C 1 29  ? -89.867  -4.845  24.263  1.00 56.34  ? 236 ASN C OD1 1 
ATOM   3196  N ND2 . ASN C 1 29  ? -91.635  -3.517  23.975  1.00 66.95  ? 236 ASN C ND2 1 
ATOM   3197  N N   . GLN C 1 30  ? -88.828  -4.430  19.225  1.00 58.94  ? 237 GLN C N   1 
ATOM   3198  C CA  . GLN C 1 30  ? -88.848  -4.400  17.741  1.00 54.75  ? 237 GLN C CA  1 
ATOM   3199  C C   . GLN C 1 30  ? -88.419  -5.761  17.212  1.00 54.30  ? 237 GLN C C   1 
ATOM   3200  O O   . GLN C 1 30  ? -88.974  -6.186  16.201  1.00 56.88  ? 237 GLN C O   1 
ATOM   3201  C CB  . GLN C 1 30  ? -87.912  -3.331  17.190  1.00 56.24  ? 237 GLN C CB  1 
ATOM   3202  C CG  . GLN C 1 30  ? -88.613  -2.271  16.360  1.00 56.00  ? 237 GLN C CG  1 
ATOM   3203  C CD  . GLN C 1 30  ? -87.629  -1.395  15.627  1.00 65.60  ? 237 GLN C CD  1 
ATOM   3204  O OE1 . GLN C 1 30  ? -86.751  -0.778  16.222  1.00 66.24  ? 237 GLN C OE1 1 
ATOM   3205  N NE2 . GLN C 1 30  ? -87.772  -1.334  14.315  1.00 68.32  ? 237 GLN C NE2 1 
ATOM   3206  N N   . LEU C 1 31  ? -87.472  -6.416  17.882  1.00 54.65  ? 238 LEU C N   1 
ATOM   3207  C CA  . LEU C 1 31  ? -87.114  -7.747  17.420  1.00 51.84  ? 238 LEU C CA  1 
ATOM   3208  C C   . LEU C 1 31  ? -88.253  -8.722  17.668  1.00 58.70  ? 238 LEU C C   1 
ATOM   3209  O O   . LEU C 1 31  ? -88.561  -9.560  16.812  1.00 61.77  ? 238 LEU C O   1 
ATOM   3210  C CB  . LEU C 1 31  ? -85.832  -8.214  18.116  1.00 47.86  ? 238 LEU C CB  1 
ATOM   3211  C CG  . LEU C 1 31  ? -85.359  -9.657  17.882  1.00 45.95  ? 238 LEU C CG  1 
ATOM   3212  C CD1 . LEU C 1 31  ? -85.279  -10.031 16.400  1.00 43.98  ? 238 LEU C CD1 1 
ATOM   3213  C CD2 . LEU C 1 31  ? -84.042  -9.921  18.566  1.00 49.32  ? 238 LEU C CD2 1 
ATOM   3214  N N   . ARG C 1 32  ? -88.902  -8.612  18.826  1.00 54.10  ? 239 ARG C N   1 
ATOM   3215  C CA  . ARG C 1 32  ? -89.994  -9.519  19.137  1.00 57.59  ? 239 ARG C CA  1 
ATOM   3216  C C   . ARG C 1 32  ? -91.110  -9.383  18.108  1.00 59.56  ? 239 ARG C C   1 
ATOM   3217  O O   . ARG C 1 32  ? -91.550  -10.378 17.516  1.00 54.13  ? 239 ARG C O   1 
ATOM   3218  C CB  . ARG C 1 32  ? -90.497  -9.241  20.557  1.00 63.43  ? 239 ARG C CB  1 
ATOM   3219  C CG  . ARG C 1 32  ? -91.423  -10.309 21.128  1.00 64.36  ? 239 ARG C CG  1 
ATOM   3220  C CD  . ARG C 1 32  ? -92.451  -9.671  22.060  1.00 65.59  ? 239 ARG C CD  1 
ATOM   3221  N NE  . ARG C 1 32  ? -91.836  -8.922  23.151  1.00 55.99  ? 239 ARG C NE  1 
ATOM   3222  C CZ  . ARG C 1 32  ? -92.513  -8.395  24.159  1.00 55.39  ? 239 ARG C CZ  1 
ATOM   3223  N NH1 . ARG C 1 32  ? -93.825  -8.531  24.224  1.00 66.59  ? 239 ARG C NH1 1 
ATOM   3224  N NH2 . ARG C 1 32  ? -91.880  -7.750  25.118  1.00 57.67  ? 239 ARG C NH2 1 
ATOM   3225  N N   . LYS C 1 33  ? -91.536  -8.138  17.845  1.00 60.40  ? 240 LYS C N   1 
ATOM   3226  C CA  . LYS C 1 33  ? -92.640  -7.874  16.926  1.00 58.88  ? 240 LYS C CA  1 
ATOM   3227  C C   . LYS C 1 33  ? -92.417  -8.535  15.574  1.00 65.24  ? 240 LYS C C   1 
ATOM   3228  O O   . LYS C 1 33  ? -93.381  -8.949  14.910  1.00 62.21  ? 240 LYS C O   1 
ATOM   3229  C CB  . LYS C 1 33  ? -92.825  -6.363  16.751  1.00 49.40  ? 240 LYS C CB  1 
ATOM   3230  N N   . ALA C 1 34  ? -91.153  -8.678  15.172  1.00 60.22  ? 241 ALA C N   1 
ATOM   3231  C CA  . ALA C 1 34  ? -90.828  -9.115  13.826  1.00 58.11  ? 241 ALA C CA  1 
ATOM   3232  C C   . ALA C 1 34  ? -90.737  -10.632 13.714  1.00 55.48  ? 241 ALA C C   1 
ATOM   3233  O O   . ALA C 1 34  ? -91.137  -11.190 12.690  1.00 55.96  ? 241 ALA C O   1 
ATOM   3234  C CB  . ALA C 1 34  ? -89.526  -8.451  13.362  1.00 54.60  ? 241 ALA C CB  1 
ATOM   3235  N N   . VAL C 1 35  ? -90.297  -11.292 14.784  1.00 58.61  ? 242 VAL C N   1 
ATOM   3236  C CA  . VAL C 1 35  ? -90.345  -12.783 14.787  1.00 63.09  ? 242 VAL C CA  1 
ATOM   3237  C C   . VAL C 1 35  ? -91.828  -13.158 14.790  1.00 65.37  ? 242 VAL C C   1 
ATOM   3238  O O   . VAL C 1 35  ? -92.172  -14.139 14.142  1.00 60.80  ? 242 VAL C O   1 
ATOM   3239  C CB  . VAL C 1 35  ? -89.547  -13.425 15.942  1.00 49.65  ? 242 VAL C CB  1 
ATOM   3240  C CG1 . VAL C 1 35  ? -88.189  -12.784 16.148  1.00 45.82  ? 242 VAL C CG1 1 
ATOM   3241  C CG2 . VAL C 1 35  ? -90.314  -13.524 17.246  1.00 54.84  ? 242 VAL C CG2 1 
ATOM   3242  N N   . TYR C 1 36  ? -92.674  -12.352 15.430  1.00 62.24  ? 243 TYR C N   1 
ATOM   3243  C CA  . TYR C 1 36  ? -94.116  -12.577 15.437  1.00 60.01  ? 243 TYR C CA  1 
ATOM   3244  C C   . TYR C 1 36  ? -94.686  -12.570 14.018  1.00 66.72  ? 243 TYR C C   1 
ATOM   3245  O O   . TYR C 1 36  ? -95.516  -13.419 13.667  1.00 68.61  ? 243 TYR C O   1 
ATOM   3246  C CB  . TYR C 1 36  ? -94.817  -11.512 16.288  1.00 67.21  ? 243 TYR C CB  1 
ATOM   3247  C CG  . TYR C 1 36  ? -94.860  -11.731 17.811  1.00 68.64  ? 243 TYR C CG  1 
ATOM   3248  C CD1 . TYR C 1 36  ? -94.791  -12.994 18.373  1.00 61.47  ? 243 TYR C CD1 1 
ATOM   3249  C CD2 . TYR C 1 36  ? -94.992  -10.639 18.679  1.00 70.18  ? 243 TYR C CD2 1 
ATOM   3250  C CE1 . TYR C 1 36  ? -94.833  -13.153 19.757  1.00 69.91  ? 243 TYR C CE1 1 
ATOM   3251  C CE2 . TYR C 1 36  ? -95.042  -10.792 20.044  1.00 63.09  ? 243 TYR C CE2 1 
ATOM   3252  C CZ  . TYR C 1 36  ? -94.967  -12.043 20.581  1.00 67.94  ? 243 TYR C CZ  1 
ATOM   3253  O OH  . TYR C 1 36  ? -95.015  -12.173 21.952  1.00 69.42  ? 243 TYR C OH  1 
ATOM   3254  N N   . MET C 1 37  ? -94.246  -11.631 13.181  1.00 69.96  ? 244 MET C N   1 
ATOM   3255  C CA  . MET C 1 37  ? -94.836  -11.440 11.861  1.00 62.18  ? 244 MET C CA  1 
ATOM   3256  C C   . MET C 1 37  ? -94.246  -12.354 10.808  1.00 62.20  ? 244 MET C C   1 
ATOM   3257  O O   . MET C 1 37  ? -94.592  -12.200 9.636   1.00 71.78  ? 244 MET C O   1 
ATOM   3258  C CB  . MET C 1 37  ? -94.688  -9.974  11.420  1.00 57.15  ? 244 MET C CB  1 
ATOM   3259  N N   . MET C 1 38  ? -93.370  -13.297 11.173  1.00 63.82  ? 245 MET C N   1 
ATOM   3260  C CA  . MET C 1 38  ? -92.772  -14.104 10.112  1.00 69.62  ? 245 MET C CA  1 
ATOM   3261  C C   . MET C 1 38  ? -93.733  -15.186 9.614   1.00 79.90  ? 245 MET C C   1 
ATOM   3262  O O   . MET C 1 38  ? -94.504  -15.762 10.393  1.00 74.03  ? 245 MET C O   1 
ATOM   3263  C CB  . MET C 1 38  ? -91.476  -14.777 10.572  1.00 64.18  ? 245 MET C CB  1 
ATOM   3264  C CG  . MET C 1 38  ? -90.457  -13.879 11.246  1.00 65.01  ? 245 MET C CG  1 
ATOM   3265  S SD  . MET C 1 38  ? -89.040  -14.769 11.967  1.00 57.87  ? 245 MET C SD  1 
ATOM   3266  C CE  . MET C 1 38  ? -88.435  -15.666 10.530  1.00 58.34  ? 245 MET C CE  1 
ATOM   3267  N N   . PRO C 1 39  ? -93.747  -15.478 8.276   1.00 84.38  ? 246 PRO C N   1 
ATOM   3268  C CA  . PRO C 1 39  ? -94.551  -16.569 7.738   1.00 85.12  ? 246 PRO C CA  1 
ATOM   3269  C C   . PRO C 1 39  ? -94.003  -17.926 8.179   1.00 79.74  ? 246 PRO C C   1 
ATOM   3270  O O   . PRO C 1 39  ? -92.887  -18.248 7.844   1.00 83.22  ? 246 PRO C O   1 
ATOM   3271  C CB  . PRO C 1 39  ? -94.406  -16.464 6.217   1.00 79.87  ? 246 PRO C CB  1 
ATOM   3272  C CG  . PRO C 1 39  ? -94.070  -15.029 5.985   1.00 77.84  ? 246 PRO C CG  1 
ATOM   3273  C CD  . PRO C 1 39  ? -93.112  -14.772 7.119   1.00 76.66  ? 246 PRO C CD  1 
ATOM   3274  N N   . THR C 1 40  ? -94.834  -18.695 8.883   1.00 84.70  ? 247 THR C N   1 
ATOM   3275  C CA  . THR C 1 40  ? -94.394  -20.005 9.422   1.00 89.55  ? 247 THR C CA  1 
ATOM   3276  C C   . THR C 1 40  ? -95.389  -21.127 9.070   1.00 101.53 ? 247 THR C C   1 
ATOM   3277  O O   . THR C 1 40  ? -94.989  -22.295 9.196   1.00 102.45 ? 247 THR C O   1 
ATOM   3278  C CB  . THR C 1 40  ? -94.166  -19.910 10.937  1.00 91.84  ? 247 THR C CB  1 
ATOM   3279  O OG1 . THR C 1 40  ? -95.119  -19.016 11.516  1.00 87.68  ? 247 THR C OG1 1 
ATOM   3280  C CG2 . THR C 1 40  ? -92.766  -19.459 11.292  1.00 89.95  ? 247 THR C CG2 1 
ATOM   3281  N N   . GLU C 1 41  ? -96.621  -20.810 8.650   1.00 102.32 ? 248 GLU C N   1 
ATOM   3282  C CA  . GLU C 1 41  ? -97.565  -21.854 8.256   1.00 105.54 ? 248 GLU C CA  1 
ATOM   3283  C C   . GLU C 1 41  ? -97.045  -22.612 7.040   1.00 104.31 ? 248 GLU C C   1 
ATOM   3284  O O   . GLU C 1 41  ? -97.796  -22.897 6.109   1.00 114.92 ? 248 GLU C O   1 
ATOM   3285  C CB  . GLU C 1 41  ? -98.947  -21.259 7.958   1.00 109.78 ? 248 GLU C CB  1 
ATOM   3286  N N   . SER C 1 46  ? -92.016  -28.250 15.599  1.00 104.32 ? 253 SER C N   1 
ATOM   3287  C CA  . SER C 1 46  ? -90.727  -27.965 16.280  1.00 96.16  ? 253 SER C CA  1 
ATOM   3288  C C   . SER C 1 46  ? -89.564  -28.174 15.314  1.00 99.72  ? 253 SER C C   1 
ATOM   3289  O O   . SER C 1 46  ? -88.506  -28.655 15.761  1.00 94.61  ? 253 SER C O   1 
ATOM   3290  C CB  . SER C 1 46  ? -90.564  -28.819 17.499  1.00 92.61  ? 253 SER C CB  1 
ATOM   3291  O OG  . SER C 1 46  ? -89.581  -28.270 18.355  1.00 90.14  ? 253 SER C OG  1 
ATOM   3292  N N   . LYS C 1 47  ? -89.712  -27.815 14.041  1.00 101.11 ? 254 LYS C N   1 
ATOM   3293  C CA  . LYS C 1 47  ? -88.550  -27.944 13.123  1.00 97.74  ? 254 LYS C CA  1 
ATOM   3294  C C   . LYS C 1 47  ? -87.983  -26.564 12.789  1.00 92.03  ? 254 LYS C C   1 
ATOM   3295  O O   . LYS C 1 47  ? -86.802  -26.489 12.418  1.00 96.48  ? 254 LYS C O   1 
ATOM   3296  C CB  . LYS C 1 47  ? -88.952  -28.688 11.848  1.00 97.60  ? 254 LYS C CB  1 
ATOM   3297  N N   . SER C 1 48  ? -88.801  -25.525 12.918  1.00 85.32  ? 255 SER C N   1 
ATOM   3298  C CA  . SER C 1 48  ? -88.345  -24.154 12.586  1.00 76.86  ? 255 SER C CA  1 
ATOM   3299  C C   . SER C 1 48  ? -87.990  -23.417 13.871  1.00 76.95  ? 255 SER C C   1 
ATOM   3300  O O   . SER C 1 48  ? -88.775  -23.475 14.825  1.00 79.15  ? 255 SER C O   1 
ATOM   3301  C CB  . SER C 1 48  ? -89.394  -23.422 11.799  1.00 79.76  ? 255 SER C CB  1 
ATOM   3302  O OG  . SER C 1 48  ? -89.648  -22.123 12.308  1.00 76.74  ? 255 SER C OG  1 
ATOM   3303  N N   . VAL C 1 49  ? -86.806  -22.808 13.914  1.00 71.07  ? 256 VAL C N   1 
ATOM   3304  C CA  . VAL C 1 49  ? -86.372  -22.024 15.109  1.00 68.77  ? 256 VAL C CA  1 
ATOM   3305  C C   . VAL C 1 49  ? -87.268  -20.790 15.255  1.00 70.19  ? 256 VAL C C   1 
ATOM   3306  O O   . VAL C 1 49  ? -87.704  -20.543 16.385  1.00 72.18  ? 256 VAL C O   1 
ATOM   3307  C CB  . VAL C 1 49  ? -84.866  -21.689 15.076  1.00 67.09  ? 256 VAL C CB  1 
ATOM   3308  C CG1 . VAL C 1 49  ? -84.388  -21.084 16.383  1.00 64.21  ? 256 VAL C CG1 1 
ATOM   3309  C CG2 . VAL C 1 49  ? -84.022  -22.897 14.711  1.00 71.81  ? 256 VAL C CG2 1 
ATOM   3310  N N   . PRO C 1 50  ? -87.562  -19.990 14.205  1.00 71.43  ? 257 PRO C N   1 
ATOM   3311  C CA  . PRO C 1 50  ? -88.527  -18.899 14.317  1.00 71.88  ? 257 PRO C CA  1 
ATOM   3312  C C   . PRO C 1 50  ? -89.809  -19.283 15.065  1.00 75.80  ? 257 PRO C C   1 
ATOM   3313  O O   . PRO C 1 50  ? -90.245  -18.500 15.867  1.00 77.47  ? 257 PRO C O   1 
ATOM   3314  C CB  . PRO C 1 50  ? -88.893  -18.680 12.854  1.00 66.34  ? 257 PRO C CB  1 
ATOM   3315  C CG  . PRO C 1 50  ? -87.592  -18.840 12.135  1.00 68.23  ? 257 PRO C CG  1 
ATOM   3316  C CD  . PRO C 1 50  ? -86.897  -19.944 12.891  1.00 72.28  ? 257 PRO C CD  1 
ATOM   3317  N N   . LEU C 1 51  ? -90.369  -20.459 14.781  1.00 76.42  ? 258 LEU C N   1 
ATOM   3318  C CA  . LEU C 1 51  ? -91.643  -20.894 15.408  1.00 78.02  ? 258 LEU C CA  1 
ATOM   3319  C C   . LEU C 1 51  ? -91.471  -20.996 16.920  1.00 68.03  ? 258 LEU C C   1 
ATOM   3320  O O   . LEU C 1 51  ? -92.337  -20.493 17.642  1.00 66.83  ? 258 LEU C O   1 
ATOM   3321  C CB  . LEU C 1 51  ? -92.051  -22.246 14.822  1.00 81.34  ? 258 LEU C CB  1 
ATOM   3322  N N   . ALA C 1 52  ? -90.402  -21.650 17.362  1.00 66.31  ? 259 ALA C N   1 
ATOM   3323  C CA  . ALA C 1 52  ? -90.191  -21.806 18.812  1.00 66.92  ? 259 ALA C CA  1 
ATOM   3324  C C   . ALA C 1 52  ? -90.082  -20.448 19.501  1.00 67.80  ? 259 ALA C C   1 
ATOM   3325  O O   . ALA C 1 52  ? -90.727  -20.273 20.527  1.00 66.89  ? 259 ALA C O   1 
ATOM   3326  C CB  . ALA C 1 52  ? -88.960  -22.618 19.001  1.00 65.53  ? 259 ALA C CB  1 
ATOM   3327  N N   . LEU C 1 53  ? -89.290  -19.537 18.947  1.00 64.38  ? 260 LEU C N   1 
ATOM   3328  C CA  . LEU C 1 53  ? -89.103  -18.202 19.559  1.00 63.37  ? 260 LEU C CA  1 
ATOM   3329  C C   . LEU C 1 53  ? -90.456  -17.509 19.653  1.00 63.71  ? 260 LEU C C   1 
ATOM   3330  O O   . LEU C 1 53  ? -90.751  -16.990 20.718  1.00 63.87  ? 260 LEU C O   1 
ATOM   3331  C CB  . LEU C 1 53  ? -88.140  -17.393 18.693  1.00 66.10  ? 260 LEU C CB  1 
ATOM   3332  C CG  . LEU C 1 53  ? -86.695  -17.875 18.695  1.00 64.98  ? 260 LEU C CG  1 
ATOM   3333  C CD1 . LEU C 1 53  ? -85.941  -17.266 17.532  1.00 66.14  ? 260 LEU C CD1 1 
ATOM   3334  C CD2 . LEU C 1 53  ? -86.016  -17.521 20.002  1.00 63.24  ? 260 LEU C CD2 1 
ATOM   3335  N N   . GLN C 1 54  ? -91.233  -17.516 18.572  1.00 61.58  ? 261 GLN C N   1 
ATOM   3336  C CA  . GLN C 1 54  ? -92.582  -16.900 18.570  1.00 68.78  ? 261 GLN C CA  1 
ATOM   3337  C C   . GLN C 1 54  ? -93.372  -17.419 19.766  1.00 71.82  ? 261 GLN C C   1 
ATOM   3338  O O   . GLN C 1 54  ? -93.924  -16.598 20.497  1.00 66.47  ? 261 GLN C O   1 
ATOM   3339  C CB  . GLN C 1 54  ? -93.348  -17.304 17.317  1.00 67.17  ? 261 GLN C CB  1 
ATOM   3340  C CG  . GLN C 1 54  ? -92.961  -16.556 16.056  1.00 70.19  ? 261 GLN C CG  1 
ATOM   3341  C CD  . GLN C 1 54  ? -93.421  -17.275 14.811  1.00 71.21  ? 261 GLN C CD  1 
ATOM   3342  O OE1 . GLN C 1 54  ? -93.919  -18.395 14.861  1.00 75.16  ? 261 GLN C OE1 1 
ATOM   3343  N NE2 . GLN C 1 54  ? -93.261  -16.629 13.670  1.00 71.35  ? 261 GLN C NE2 1 
ATOM   3344  N N   . ARG C 1 55  ? -93.436  -18.738 19.926  1.00 70.04  ? 262 ARG C N   1 
ATOM   3345  C CA  . ARG C 1 55  ? -94.166  -19.354 21.056  1.00 69.70  ? 262 ARG C CA  1 
ATOM   3346  C C   . ARG C 1 55  ? -93.555  -18.886 22.368  1.00 67.18  ? 262 ARG C C   1 
ATOM   3347  O O   . ARG C 1 55  ? -94.302  -18.377 23.189  1.00 69.03  ? 262 ARG C O   1 
ATOM   3348  C CB  . ARG C 1 55  ? -94.076  -20.877 20.966  1.00 65.88  ? 262 ARG C CB  1 
ATOM   3349  N N   . VAL C 1 56  ? -92.252  -19.086 22.541  1.00 59.58  ? 263 VAL C N   1 
ATOM   3350  C CA  . VAL C 1 56  ? -91.569  -18.679 23.798  1.00 58.93  ? 263 VAL C CA  1 
ATOM   3351  C C   . VAL C 1 56  ? -91.935  -17.224 24.065  1.00 60.33  ? 263 VAL C C   1 
ATOM   3352  O O   . VAL C 1 56  ? -92.202  -16.902 25.213  1.00 61.79  ? 263 VAL C O   1 
ATOM   3353  C CB  . VAL C 1 56  ? -90.049  -18.905 23.720  1.00 61.18  ? 263 VAL C CB  1 
ATOM   3354  C CG1 . VAL C 1 56  ? -89.301  -18.221 24.851  1.00 57.53  ? 263 VAL C CG1 1 
ATOM   3355  C CG2 . VAL C 1 56  ? -89.706  -20.384 23.690  1.00 65.01  ? 263 VAL C CG2 1 
ATOM   3356  N N   . PHE C 1 57  ? -92.025  -16.405 23.025  1.00 62.63  ? 264 PHE C N   1 
ATOM   3357  C CA  . PHE C 1 57  ? -92.284  -14.964 23.267  1.00 69.45  ? 264 PHE C CA  1 
ATOM   3358  C C   . PHE C 1 57  ? -93.765  -14.739 23.577  1.00 71.23  ? 264 PHE C C   1 
ATOM   3359  O O   . PHE C 1 57  ? -94.043  -13.925 24.451  1.00 70.09  ? 264 PHE C O   1 
ATOM   3360  C CB  . PHE C 1 57  ? -91.797  -14.134 22.077  1.00 71.98  ? 264 PHE C CB  1 
ATOM   3361  C CG  . PHE C 1 57  ? -90.301  -14.058 21.898  1.00 68.86  ? 264 PHE C CG  1 
ATOM   3362  C CD1 . PHE C 1 57  ? -89.431  -14.505 22.879  1.00 68.26  ? 264 PHE C CD1 1 
ATOM   3363  C CD2 . PHE C 1 57  ? -89.759  -13.542 20.735  1.00 65.37  ? 264 PHE C CD2 1 
ATOM   3364  C CE1 . PHE C 1 57  ? -88.059  -14.437 22.697  1.00 68.81  ? 264 PHE C CE1 1 
ATOM   3365  C CE2 . PHE C 1 57  ? -88.388  -13.471 20.555  1.00 65.68  ? 264 PHE C CE2 1 
ATOM   3366  C CZ  . PHE C 1 57  ? -87.539  -13.919 21.536  1.00 66.66  ? 264 PHE C CZ  1 
ATOM   3367  N N   . TYR C 1 58  ? -94.676  -15.415 22.874  1.00 71.87  ? 265 TYR C N   1 
ATOM   3368  C CA  . TYR C 1 58  ? -96.127  -15.321 23.177  1.00 71.30  ? 265 TYR C CA  1 
ATOM   3369  C C   . TYR C 1 58  ? -96.365  -15.824 24.591  1.00 73.27  ? 265 TYR C C   1 
ATOM   3370  O O   . TYR C 1 58  ? -97.067  -15.165 25.358  1.00 69.38  ? 265 TYR C O   1 
ATOM   3371  C CB  . TYR C 1 58  ? -96.954  -16.192 22.234  1.00 68.48  ? 265 TYR C CB  1 
ATOM   3372  C CG  . TYR C 1 58  ? -98.439  -15.944 22.296  1.00 73.19  ? 265 TYR C CG  1 
ATOM   3373  C CD1 . TYR C 1 58  ? -99.258  -16.672 23.143  1.00 74.80  ? 265 TYR C CD1 1 
ATOM   3374  C CD2 . TYR C 1 58  ? -99.027  -14.973 21.507  1.00 87.49  ? 265 TYR C CD2 1 
ATOM   3375  C CE1 . TYR C 1 58  ? -100.620 -16.436 23.210  1.00 79.20  ? 265 TYR C CE1 1 
ATOM   3376  C CE2 . TYR C 1 58  ? -100.389 -14.729 21.556  1.00 87.49  ? 265 TYR C CE2 1 
ATOM   3377  C CZ  . TYR C 1 58  ? -101.188 -15.460 22.413  1.00 86.94  ? 265 TYR C CZ  1 
ATOM   3378  O OH  . TYR C 1 58  ? -102.529 -15.216 22.462  1.00 93.88  ? 265 TYR C OH  1 
ATOM   3379  N N   . GLU C 1 59  ? -95.812  -16.992 24.898  1.00 64.18  ? 266 GLU C N   1 
ATOM   3380  C CA  . GLU C 1 59  ? -96.001  -17.571 26.242  1.00 65.72  ? 266 GLU C CA  1 
ATOM   3381  C C   . GLU C 1 59  ? -95.400  -16.605 27.263  1.00 73.11  ? 266 GLU C C   1 
ATOM   3382  O O   . GLU C 1 59  ? -96.088  -16.282 28.222  1.00 77.43  ? 266 GLU C O   1 
ATOM   3383  C CB  . GLU C 1 59  ? -95.389  -18.966 26.278  1.00 56.93  ? 266 GLU C CB  1 
ATOM   3384  N N   . LEU C 1 60  ? -94.174  -16.141 27.046  1.00 71.21  ? 267 LEU C N   1 
ATOM   3385  C CA  . LEU C 1 60  ? -93.587  -15.137 27.964  1.00 69.24  ? 267 LEU C CA  1 
ATOM   3386  C C   . LEU C 1 60  ? -94.524  -13.935 28.053  1.00 73.27  ? 267 LEU C C   1 
ATOM   3387  O O   . LEU C 1 60  ? -94.581  -13.328 29.131  1.00 73.76  ? 267 LEU C O   1 
ATOM   3388  C CB  . LEU C 1 60  ? -92.211  -14.714 27.451  1.00 70.33  ? 267 LEU C CB  1 
ATOM   3389  C CG  . LEU C 1 60  ? -91.013  -15.315 28.179  1.00 76.14  ? 267 LEU C CG  1 
ATOM   3390  C CD1 . LEU C 1 60  ? -89.740  -15.104 27.378  1.00 76.50  ? 267 LEU C CD1 1 
ATOM   3391  C CD2 . LEU C 1 60  ? -90.873  -14.712 29.564  1.00 67.78  ? 267 LEU C CD2 1 
ATOM   3392  N N   . GLN C 1 61  ? -95.229  -13.603 26.970  1.00 74.21  ? 268 GLN C N   1 
ATOM   3393  C CA  . GLN C 1 61  ? -96.062  -12.372 27.043  1.00 77.76  ? 268 GLN C CA  1 
ATOM   3394  C C   . GLN C 1 61  ? -97.378  -12.634 27.771  1.00 75.96  ? 268 GLN C C   1 
ATOM   3395  O O   . GLN C 1 61  ? -97.826  -11.727 28.483  1.00 71.50  ? 268 GLN C O   1 
ATOM   3396  C CB  . GLN C 1 61  ? -96.373  -11.842 25.641  1.00 75.88  ? 268 GLN C CB  1 
ATOM   3397  C CG  . GLN C 1 61  ? -96.629  -10.345 25.586  1.00 68.12  ? 268 GLN C CG  1 
ATOM   3398  C CD  . GLN C 1 61  ? -96.926  -9.869  24.186  1.00 69.19  ? 268 GLN C CD  1 
ATOM   3399  O OE1 . GLN C 1 61  ? -96.185  -10.141 23.249  1.00 73.63  ? 268 GLN C OE1 1 
ATOM   3400  N NE2 . GLN C 1 61  ? -98.016  -9.138  24.036  1.00 83.32  ? 268 GLN C NE2 1 
ATOM   3401  N N   . HIS C 1 62  ? -97.954  -13.832 27.644  1.00 75.30  ? 269 HIS C N   1 
ATOM   3402  C CA  . HIS C 1 62  ? -99.324  -14.029 28.195  1.00 78.75  ? 269 HIS C CA  1 
ATOM   3403  C C   . HIS C 1 62  ? -99.426  -15.086 29.307  1.00 77.91  ? 269 HIS C C   1 
ATOM   3404  O O   . HIS C 1 62  ? -100.411 -15.012 30.055  1.00 84.81  ? 269 HIS C O   1 
ATOM   3405  C CB  . HIS C 1 62  ? -100.293 -14.275 27.028  1.00 77.66  ? 269 HIS C CB  1 
ATOM   3406  C CG  . HIS C 1 62  ? -100.166 -13.243 25.964  1.00 74.54  ? 269 HIS C CG  1 
ATOM   3407  N ND1 . HIS C 1 62  ? -99.523  -13.489 24.777  1.00 75.41  ? 269 HIS C ND1 1 
ATOM   3408  C CD2 . HIS C 1 62  ? -100.538 -11.948 25.935  1.00 82.92  ? 269 HIS C CD2 1 
ATOM   3409  C CE1 . HIS C 1 62  ? -99.536  -12.402 24.041  1.00 82.21  ? 269 HIS C CE1 1 
ATOM   3410  N NE2 . HIS C 1 62  ? -100.141 -11.439 24.734  1.00 80.61  ? 269 HIS C NE2 1 
ATOM   3411  N N   . SER C 1 63  ? -98.474  -16.005 29.445  1.00 72.35  ? 270 SER C N   1 
ATOM   3412  C CA  . SER C 1 63  ? -98.561  -16.964 30.577  1.00 75.07  ? 270 SER C CA  1 
ATOM   3413  C C   . SER C 1 63  ? -98.278  -16.256 31.895  1.00 84.99  ? 270 SER C C   1 
ATOM   3414  O O   . SER C 1 63  ? -97.599  -15.223 31.868  1.00 80.40  ? 270 SER C O   1 
ATOM   3415  C CB  . SER C 1 63  ? -97.625  -18.127 30.402  1.00 74.73  ? 270 SER C CB  1 
ATOM   3416  O OG  . SER C 1 63  ? -97.539  -18.912 31.581  1.00 75.29  ? 270 SER C OG  1 
ATOM   3417  N N   . ASP C 1 64  ? -98.750  -16.831 33.006  1.00 91.63  ? 271 ASP C N   1 
ATOM   3418  C CA  . ASP C 1 64  ? -98.537  -16.265 34.364  1.00 89.86  ? 271 ASP C CA  1 
ATOM   3419  C C   . ASP C 1 64  ? -97.563  -17.161 35.125  1.00 87.91  ? 271 ASP C C   1 
ATOM   3420  O O   . ASP C 1 64  ? -97.032  -16.711 36.150  1.00 88.22  ? 271 ASP C O   1 
ATOM   3421  C CB  . ASP C 1 64  ? -99.862  -16.158 35.115  1.00 85.79  ? 271 ASP C CB  1 
ATOM   3422  C CG  . ASP C 1 64  ? -100.770 -17.361 34.927  1.00 100.04 ? 271 ASP C CG  1 
ATOM   3423  O OD1 . ASP C 1 64  ? -101.489 -17.398 33.911  1.00 100.08 ? 271 ASP C OD1 1 
ATOM   3424  O OD2 . ASP C 1 64  ? -100.752 -18.249 35.799  1.00 107.34 ? 271 ASP C OD2 1 
ATOM   3425  N N   . LYS C 1 65  ? -97.362  -18.388 34.654  1.00 83.09  ? 272 LYS C N   1 
ATOM   3426  C CA  . LYS C 1 65  ? -96.431  -19.326 35.259  1.00 85.27  ? 272 LYS C CA  1 
ATOM   3427  C C   . LYS C 1 65  ? -95.162  -19.389 34.429  1.00 80.78  ? 272 LYS C C   1 
ATOM   3428  O O   . LYS C 1 65  ? -95.169  -19.034 33.245  1.00 81.07  ? 272 LYS C O   1 
ATOM   3429  C CB  . LYS C 1 65  ? -97.059  -20.722 35.365  1.00 80.82  ? 272 LYS C CB  1 
ATOM   3430  N N   . PRO C 1 66  ? -94.039  -19.790 35.029  1.00 75.19  ? 273 PRO C N   1 
ATOM   3431  C CA  . PRO C 1 66  ? -92.782  -19.851 34.273  1.00 73.68  ? 273 PRO C CA  1 
ATOM   3432  C C   . PRO C 1 66  ? -92.912  -20.671 32.996  1.00 71.91  ? 273 PRO C C   1 
ATOM   3433  O O   . PRO C 1 66  ? -93.691  -21.622 32.919  1.00 74.31  ? 273 PRO C O   1 
ATOM   3434  C CB  . PRO C 1 66  ? -91.808  -20.483 35.268  1.00 72.15  ? 273 PRO C CB  1 
ATOM   3435  C CG  . PRO C 1 66  ? -92.275  -19.948 36.578  1.00 69.39  ? 273 PRO C CG  1 
ATOM   3436  C CD  . PRO C 1 66  ? -93.799  -19.914 36.478  1.00 75.19  ? 273 PRO C CD  1 
ATOM   3437  N N   . VAL C 1 67  ? -92.137  -20.268 31.984  1.00 75.45  ? 274 VAL C N   1 
ATOM   3438  C CA  . VAL C 1 67  ? -92.299  -20.701 30.599  1.00 73.46  ? 274 VAL C CA  1 
ATOM   3439  C C   . VAL C 1 67  ? -91.256  -21.754 30.257  1.00 68.93  ? 274 VAL C C   1 
ATOM   3440  O O   . VAL C 1 67  ? -90.123  -21.719 30.744  1.00 69.21  ? 274 VAL C O   1 
ATOM   3441  C CB  . VAL C 1 67  ? -92.190  -19.492 29.648  1.00 71.26  ? 274 VAL C CB  1 
ATOM   3442  C CG1 . VAL C 1 67  ? -92.642  -19.872 28.258  1.00 69.81  ? 274 VAL C CG1 1 
ATOM   3443  C CG2 . VAL C 1 67  ? -92.993  -18.333 30.191  1.00 69.70  ? 274 VAL C CG2 1 
ATOM   3444  N N   . GLY C 1 68  ? -91.632  -22.687 29.391  1.00 64.02  ? 275 GLY C N   1 
ATOM   3445  C CA  . GLY C 1 68  ? -90.742  -23.748 28.979  1.00 72.63  ? 275 GLY C CA  1 
ATOM   3446  C C   . GLY C 1 68  ? -90.043  -23.452 27.662  1.00 83.17  ? 275 GLY C C   1 
ATOM   3447  O O   . GLY C 1 68  ? -90.499  -22.636 26.858  1.00 83.36  ? 275 GLY C O   1 
ATOM   3448  N N   . THR C 1 69  ? -88.915  -24.140 27.446  1.00 79.12  ? 276 THR C N   1 
ATOM   3449  C CA  . THR C 1 69  ? -88.084  -23.929 26.265  1.00 77.92  ? 276 THR C CA  1 
ATOM   3450  C C   . THR C 1 69  ? -87.811  -25.215 25.490  1.00 73.46  ? 276 THR C C   1 
ATOM   3451  O O   . THR C 1 69  ? -86.940  -25.228 24.614  1.00 71.80  ? 276 THR C O   1 
ATOM   3452  C CB  . THR C 1 69  ? -86.748  -23.266 26.657  1.00 79.66  ? 276 THR C CB  1 
ATOM   3453  O OG1 . THR C 1 69  ? -85.865  -24.226 27.265  1.00 68.64  ? 276 THR C OG1 1 
ATOM   3454  C CG2 . THR C 1 69  ? -86.980  -22.115 27.632  1.00 77.63  ? 276 THR C CG2 1 
ATOM   3455  N N   . LYS C 1 70  ? -88.534  -26.292 25.777  1.00 78.20  ? 277 LYS C N   1 
ATOM   3456  C CA  . LYS C 1 70  ? -88.131  -27.589 25.251  1.00 77.62  ? 277 LYS C CA  1 
ATOM   3457  C C   . LYS C 1 70  ? -88.208  -27.613 23.727  1.00 75.36  ? 277 LYS C C   1 
ATOM   3458  O O   . LYS C 1 70  ? -87.273  -28.073 23.060  1.00 79.71  ? 277 LYS C O   1 
ATOM   3459  C CB  . LYS C 1 70  ? -88.984  -28.699 25.881  1.00 75.66  ? 277 LYS C CB  1 
ATOM   3460  N N   . LYS C 1 71  ? -89.304  -27.101 23.152  1.00 68.63  ? 278 LYS C N   1 
ATOM   3461  C CA  . LYS C 1 71  ? -89.453  -27.160 21.700  1.00 78.81  ? 278 LYS C CA  1 
ATOM   3462  C C   . LYS C 1 71  ? -88.365  -26.349 20.994  1.00 80.08  ? 278 LYS C C   1 
ATOM   3463  O O   . LYS C 1 71  ? -87.917  -26.730 19.904  1.00 77.73  ? 278 LYS C O   1 
ATOM   3464  C CB  . LYS C 1 71  ? -90.854  -26.688 21.286  1.00 81.90  ? 278 LYS C CB  1 
ATOM   3465  N N   . LEU C 1 72  ? -87.901  -25.257 21.618  1.00 79.72  ? 279 LEU C N   1 
ATOM   3466  C CA  . LEU C 1 72  ? -86.820  -24.463 21.036  1.00 74.25  ? 279 LEU C CA  1 
ATOM   3467  C C   . LEU C 1 72  ? -85.550  -25.287 20.909  1.00 73.64  ? 279 LEU C C   1 
ATOM   3468  O O   . LEU C 1 72  ? -84.930  -25.343 19.840  1.00 74.47  ? 279 LEU C O   1 
ATOM   3469  C CB  . LEU C 1 72  ? -86.567  -23.206 21.876  1.00 69.02  ? 279 LEU C CB  1 
ATOM   3470  C CG  . LEU C 1 72  ? -85.471  -22.222 21.427  1.00 68.49  ? 279 LEU C CG  1 
ATOM   3471  C CD1 . LEU C 1 72  ? -85.618  -21.787 19.974  1.00 69.41  ? 279 LEU C CD1 1 
ATOM   3472  C CD2 . LEU C 1 72  ? -85.454  -20.996 22.311  1.00 62.23  ? 279 LEU C CD2 1 
ATOM   3473  N N   . THR C 1 73  ? -85.151  -25.952 21.986  1.00 74.89  ? 280 THR C N   1 
ATOM   3474  C CA  . THR C 1 73  ? -83.965  -26.778 21.881  1.00 72.00  ? 280 THR C CA  1 
ATOM   3475  C C   . THR C 1 73  ? -84.186  -27.943 20.929  1.00 73.68  ? 280 THR C C   1 
ATOM   3476  O O   . THR C 1 73  ? -83.212  -28.493 20.416  1.00 71.13  ? 280 THR C O   1 
ATOM   3477  C CB  . THR C 1 73  ? -83.543  -27.236 23.262  1.00 69.70  ? 280 THR C CB  1 
ATOM   3478  O OG1 . THR C 1 73  ? -84.640  -27.872 23.915  1.00 76.13  ? 280 THR C OG1 1 
ATOM   3479  C CG2 . THR C 1 73  ? -83.156  -26.039 24.047  1.00 67.28  ? 280 THR C CG2 1 
ATOM   3480  N N   . LYS C 1 74  ? -85.444  -28.270 20.618  1.00 75.66  ? 281 LYS C N   1 
ATOM   3481  C CA  . LYS C 1 74  ? -85.701  -29.253 19.571  1.00 80.79  ? 281 LYS C CA  1 
ATOM   3482  C C   . LYS C 1 74  ? -85.628  -28.614 18.192  1.00 78.31  ? 281 LYS C C   1 
ATOM   3483  O O   . LYS C 1 74  ? -85.225  -29.256 17.220  1.00 77.60  ? 281 LYS C O   1 
ATOM   3484  C CB  . LYS C 1 74  ? -87.067  -29.923 19.766  1.00 82.86  ? 281 LYS C CB  1 
ATOM   3485  N N   . SER C 1 75  ? -86.027  -27.353 18.077  1.00 77.85  ? 282 SER C N   1 
ATOM   3486  C CA  . SER C 1 75  ? -85.751  -26.615 16.852  1.00 72.02  ? 282 SER C CA  1 
ATOM   3487  C C   . SER C 1 75  ? -84.264  -26.605 16.535  1.00 73.66  ? 282 SER C C   1 
ATOM   3488  O O   . SER C 1 75  ? -83.876  -26.607 15.358  1.00 82.11  ? 282 SER C O   1 
ATOM   3489  C CB  . SER C 1 75  ? -86.259  -25.200 16.992  1.00 73.72  ? 282 SER C CB  1 
ATOM   3490  O OG  . SER C 1 75  ? -85.364  -24.458 17.797  1.00 78.12  ? 282 SER C OG  1 
ATOM   3491  N N   . PHE C 1 76  ? -83.447  -26.560 17.582  1.00 68.93  ? 283 PHE C N   1 
ATOM   3492  C CA  . PHE C 1 76  ? -81.980  -26.494 17.403  1.00 61.98  ? 283 PHE C CA  1 
ATOM   3493  C C   . PHE C 1 76  ? -81.470  -27.799 16.816  1.00 68.07  ? 283 PHE C C   1 
ATOM   3494  O O   . PHE C 1 76  ? -80.271  -27.887 16.536  1.00 71.80  ? 283 PHE C O   1 
ATOM   3495  C CB  . PHE C 1 76  ? -81.321  -26.293 18.760  1.00 66.32  ? 283 PHE C CB  1 
ATOM   3496  C CG  . PHE C 1 76  ? -81.462  -24.922 19.364  1.00 68.23  ? 283 PHE C CG  1 
ATOM   3497  C CD1 . PHE C 1 76  ? -82.158  -23.916 18.716  1.00 65.66  ? 283 PHE C CD1 1 
ATOM   3498  C CD2 . PHE C 1 76  ? -80.881  -24.639 20.586  1.00 66.98  ? 283 PHE C CD2 1 
ATOM   3499  C CE1 . PHE C 1 76  ? -82.278  -22.661 19.283  1.00 65.66  ? 283 PHE C CE1 1 
ATOM   3500  C CE2 . PHE C 1 76  ? -80.996  -23.379 21.146  1.00 64.70  ? 283 PHE C CE2 1 
ATOM   3501  C CZ  . PHE C 1 76  ? -81.698  -22.394 20.498  1.00 65.40  ? 283 PHE C CZ  1 
ATOM   3502  N N   . GLY C 1 77  ? -82.350  -28.783 16.655  1.00 72.37  ? 284 GLY C N   1 
ATOM   3503  C CA  . GLY C 1 77  ? -81.931  -30.109 16.168  1.00 70.69  ? 284 GLY C CA  1 
ATOM   3504  C C   . GLY C 1 77  ? -81.232  -30.891 17.256  1.00 74.30  ? 284 GLY C C   1 
ATOM   3505  O O   . GLY C 1 77  ? -80.409  -31.759 16.927  1.00 80.30  ? 284 GLY C O   1 
ATOM   3506  N N   . TRP C 1 78  ? -81.550  -30.594 18.508  1.00 67.87  ? 285 TRP C N   1 
ATOM   3507  C CA  . TRP C 1 78  ? -80.858  -31.253 19.636  1.00 72.30  ? 285 TRP C CA  1 
ATOM   3508  C C   . TRP C 1 78  ? -81.720  -32.379 20.200  1.00 78.76  ? 285 TRP C C   1 
ATOM   3509  O O   . TRP C 1 78  ? -82.887  -32.519 19.785  1.00 72.94  ? 285 TRP C O   1 
ATOM   3510  C CB  . TRP C 1 78  ? -80.577  -30.226 20.725  1.00 74.57  ? 285 TRP C CB  1 
ATOM   3511  C CG  . TRP C 1 78  ? -79.441  -29.288 20.485  1.00 69.78  ? 285 TRP C CG  1 
ATOM   3512  C CD1 . TRP C 1 78  ? -78.592  -29.241 19.420  1.00 66.35  ? 285 TRP C CD1 1 
ATOM   3513  C CD2 . TRP C 1 78  ? -79.028  -28.246 21.380  1.00 69.75  ? 285 TRP C CD2 1 
ATOM   3514  N NE1 . TRP C 1 78  ? -77.680  -28.236 19.591  1.00 68.60  ? 285 TRP C NE1 1 
ATOM   3515  C CE2 . TRP C 1 78  ? -77.922  -27.610 20.785  1.00 73.55  ? 285 TRP C CE2 1 
ATOM   3516  C CE3 . TRP C 1 78  ? -79.487  -27.796 22.621  1.00 69.61  ? 285 TRP C CE3 1 
ATOM   3517  C CZ2 . TRP C 1 78  ? -77.268  -26.546 21.398  1.00 73.06  ? 285 TRP C CZ2 1 
ATOM   3518  C CZ3 . TRP C 1 78  ? -78.842  -26.740 23.221  1.00 69.27  ? 285 TRP C CZ3 1 
ATOM   3519  C CH2 . TRP C 1 78  ? -77.750  -26.124 22.614  1.00 66.48  ? 285 TRP C CH2 1 
ATOM   3520  N N   . GLU C 1 79  ? -81.169  -33.134 21.146  1.00 79.09  ? 286 GLU C N   1 
ATOM   3521  C CA  . GLU C 1 79  ? -81.949  -34.213 21.799  1.00 82.01  ? 286 GLU C CA  1 
ATOM   3522  C C   . GLU C 1 79  ? -82.527  -33.667 23.109  1.00 84.79  ? 286 GLU C C   1 
ATOM   3523  O O   . GLU C 1 79  ? -83.421  -32.805 23.032  1.00 92.16  ? 286 GLU C O   1 
ATOM   3524  C CB  . GLU C 1 79  ? -81.065  -35.443 21.994  1.00 78.53  ? 286 GLU C CB  1 
ATOM   3525  N N   . THR C 1 80  ? -82.045  -34.150 24.253  1.00 75.14  ? 287 THR C N   1 
ATOM   3526  C CA  . THR C 1 80  ? -82.585  -33.711 25.564  1.00 78.06  ? 287 THR C CA  1 
ATOM   3527  C C   . THR C 1 80  ? -81.421  -33.636 26.550  1.00 80.33  ? 287 THR C C   1 
ATOM   3528  O O   . THR C 1 80  ? -81.489  -32.805 27.465  1.00 78.57  ? 287 THR C O   1 
ATOM   3529  C CB  . THR C 1 80  ? -83.753  -34.602 26.011  1.00 78.67  ? 287 THR C CB  1 
ATOM   3530  O OG1 . THR C 1 80  ? -84.135  -34.223 27.333  1.00 85.44  ? 287 THR C OG1 1 
ATOM   3531  C CG2 . THR C 1 80  ? -83.429  -36.081 25.976  1.00 82.10  ? 287 THR C CG2 1 
ATOM   3532  N N   . LEU C 1 81  ? -80.397  -34.468 26.366  1.00 75.30  ? 288 LEU C N   1 
ATOM   3533  C CA  . LEU C 1 81  ? -79.181  -34.360 27.210  1.00 74.28  ? 288 LEU C CA  1 
ATOM   3534  C C   . LEU C 1 81  ? -78.409  -33.138 26.728  1.00 81.40  ? 288 LEU C C   1 
ATOM   3535  O O   . LEU C 1 81  ? -77.557  -32.642 27.478  1.00 71.82  ? 288 LEU C O   1 
ATOM   3536  C CB  . LEU C 1 81  ? -78.338  -35.622 27.036  1.00 69.16  ? 288 LEU C CB  1 
ATOM   3537  N N   . ASP C 1 82  ? -78.676  -32.714 25.495  1.00 82.70  ? 289 ASP C N   1 
ATOM   3538  C CA  . ASP C 1 82  ? -78.022  -31.511 24.938  1.00 73.74  ? 289 ASP C CA  1 
ATOM   3539  C C   . ASP C 1 82  ? -78.467  -30.321 25.790  1.00 78.18  ? 289 ASP C C   1 
ATOM   3540  O O   . ASP C 1 82  ? -77.710  -29.341 25.856  1.00 77.24  ? 289 ASP C O   1 
ATOM   3541  C CB  . ASP C 1 82  ? -78.331  -31.417 23.446  1.00 73.54  ? 289 ASP C CB  1 
ATOM   3542  C CG  . ASP C 1 82  ? -77.594  -32.436 22.597  1.00 74.10  ? 289 ASP C CG  1 
ATOM   3543  O OD1 . ASP C 1 82  ? -76.397  -32.647 22.850  1.00 75.71  ? 289 ASP C OD1 1 
ATOM   3544  O OD2 . ASP C 1 82  ? -78.222  -32.998 21.685  1.00 67.75  ? 289 ASP C OD2 1 
ATOM   3545  N N   . SER C 1 83  ? -79.634  -30.414 26.434  1.00 74.27  ? 290 SER C N   1 
ATOM   3546  C CA  . SER C 1 83  ? -80.058  -29.346 27.339  1.00 71.64  ? 290 SER C CA  1 
ATOM   3547  C C   . SER C 1 83  ? -79.414  -29.438 28.711  1.00 72.18  ? 290 SER C C   1 
ATOM   3548  O O   . SER C 1 83  ? -79.872  -28.756 29.636  1.00 74.59  ? 290 SER C O   1 
ATOM   3549  C CB  . SER C 1 83  ? -81.586  -29.315 27.494  1.00 70.85  ? 290 SER C CB  1 
ATOM   3550  O OG  . SER C 1 83  ? -82.248  -29.299 26.238  1.00 73.25  ? 290 SER C OG  1 
ATOM   3551  N N   . PHE C 1 84  ? -78.351  -30.224 28.864  1.00 68.50  ? 291 PHE C N   1 
ATOM   3552  C CA  . PHE C 1 84  ? -77.656  -30.334 30.136  1.00 70.34  ? 291 PHE C CA  1 
ATOM   3553  C C   . PHE C 1 84  ? -76.199  -29.884 30.082  1.00 74.51  ? 291 PHE C C   1 
ATOM   3554  O O   . PHE C 1 84  ? -75.513  -29.937 31.114  1.00 73.72  ? 291 PHE C O   1 
ATOM   3555  C CB  . PHE C 1 84  ? -77.744  -31.780 30.651  1.00 78.19  ? 291 PHE C CB  1 
ATOM   3556  C CG  . PHE C 1 84  ? -79.053  -32.098 31.329  1.00 71.23  ? 291 PHE C CG  1 
ATOM   3557  C CD1 . PHE C 1 84  ? -79.267  -31.751 32.646  1.00 64.77  ? 291 PHE C CD1 1 
ATOM   3558  C CD2 . PHE C 1 84  ? -80.074  -32.722 30.635  1.00 78.73  ? 291 PHE C CD2 1 
ATOM   3559  C CE1 . PHE C 1 84  ? -80.470  -32.021 33.271  1.00 66.64  ? 291 PHE C CE1 1 
ATOM   3560  C CE2 . PHE C 1 84  ? -81.282  -32.995 31.253  1.00 77.28  ? 291 PHE C CE2 1 
ATOM   3561  C CZ  . PHE C 1 84  ? -81.475  -32.641 32.579  1.00 72.88  ? 291 PHE C CZ  1 
ATOM   3562  N N   . MET C 1 85  ? -75.701  -29.453 28.921  1.00 77.92  ? 292 MET C N   1 
ATOM   3563  C CA  . MET C 1 85  ? -74.352  -28.908 28.801  1.00 74.54  ? 292 MET C CA  1 
ATOM   3564  C C   . MET C 1 85  ? -74.386  -27.384 28.893  1.00 72.26  ? 292 MET C C   1 
ATOM   3565  O O   . MET C 1 85  ? -75.307  -26.734 28.381  1.00 65.72  ? 292 MET C O   1 
ATOM   3566  C CB  . MET C 1 85  ? -73.692  -29.342 27.492  1.00 68.59  ? 292 MET C CB  1 
ATOM   3567  C CG  . MET C 1 85  ? -72.366  -28.676 27.242  1.00 66.73  ? 292 MET C CG  1 
ATOM   3568  S SD  . MET C 1 85  ? -71.354  -29.514 26.015  1.00 98.09  ? 292 MET C SD  1 
ATOM   3569  C CE  . MET C 1 85  ? -69.690  -29.224 26.679  1.00 67.36  ? 292 MET C CE  1 
ATOM   3570  N N   . GLN C 1 86  ? -73.380  -26.825 29.564  1.00 71.02  ? 293 GLN C N   1 
ATOM   3571  C CA  . GLN C 1 86  ? -73.307  -25.396 29.834  1.00 67.44  ? 293 GLN C CA  1 
ATOM   3572  C C   . GLN C 1 86  ? -72.637  -24.663 28.668  1.00 68.90  ? 293 GLN C C   1 
ATOM   3573  O O   . GLN C 1 86  ? -71.664  -25.149 28.082  1.00 68.65  ? 293 GLN C O   1 
ATOM   3574  C CB  . GLN C 1 86  ? -72.545  -25.155 31.142  1.00 63.77  ? 293 GLN C CB  1 
ATOM   3575  N N   . HIS C 1 87  ? -73.159  -23.487 28.327  1.00 67.75  ? 294 HIS C N   1 
ATOM   3576  C CA  . HIS C 1 87  ? -72.719  -22.808 27.116  1.00 64.47  ? 294 HIS C CA  1 
ATOM   3577  C C   . HIS C 1 87  ? -72.476  -21.325 27.378  1.00 63.77  ? 294 HIS C C   1 
ATOM   3578  O O   . HIS C 1 87  ? -72.692  -20.812 28.479  1.00 62.19  ? 294 HIS C O   1 
ATOM   3579  C CB  . HIS C 1 87  ? -73.733  -23.014 25.988  1.00 62.89  ? 294 HIS C CB  1 
ATOM   3580  C CG  . HIS C 1 87  ? -73.553  -24.309 25.263  1.00 64.56  ? 294 HIS C CG  1 
ATOM   3581  N ND1 . HIS C 1 87  ? -74.602  -25.159 24.984  1.00 60.95  ? 294 HIS C ND1 1 
ATOM   3582  C CD2 . HIS C 1 87  ? -72.441  -24.906 24.772  1.00 59.32  ? 294 HIS C CD2 1 
ATOM   3583  C CE1 . HIS C 1 87  ? -74.145  -26.221 24.346  1.00 64.32  ? 294 HIS C CE1 1 
ATOM   3584  N NE2 . HIS C 1 87  ? -72.837  -26.091 24.204  1.00 65.38  ? 294 HIS C NE2 1 
ATOM   3585  N N   . ASP C 1 88  ? -72.016  -20.643 26.329  1.00 64.51  ? 295 ASP C N   1 
ATOM   3586  C CA  . ASP C 1 88  ? -71.646  -19.233 26.365  1.00 53.62  ? 295 ASP C CA  1 
ATOM   3587  C C   . ASP C 1 88  ? -72.763  -18.415 25.737  1.00 53.02  ? 295 ASP C C   1 
ATOM   3588  O O   . ASP C 1 88  ? -73.173  -18.681 24.601  1.00 53.31  ? 295 ASP C O   1 
ATOM   3589  C CB  . ASP C 1 88  ? -70.324  -19.031 25.623  1.00 50.41  ? 295 ASP C CB  1 
ATOM   3590  C CG  . ASP C 1 88  ? -70.001  -17.585 25.373  1.00 57.70  ? 295 ASP C CG  1 
ATOM   3591  O OD1 . ASP C 1 88  ? -70.561  -16.987 24.425  1.00 57.76  ? 295 ASP C OD1 1 
ATOM   3592  O OD2 . ASP C 1 88  ? -69.158  -17.047 26.115  1.00 58.89  ? 295 ASP C OD2 1 
ATOM   3593  N N   . VAL C 1 89  ? -73.297  -17.455 26.485  1.00 54.69  ? 296 VAL C N   1 
ATOM   3594  C CA  . VAL C 1 89  ? -74.486  -16.677 26.025  1.00 56.42  ? 296 VAL C CA  1 
ATOM   3595  C C   . VAL C 1 89  ? -74.202  -15.955 24.710  1.00 54.95  ? 296 VAL C C   1 
ATOM   3596  O O   . VAL C 1 89  ? -75.136  -15.816 23.907  1.00 50.96  ? 296 VAL C O   1 
ATOM   3597  C CB  . VAL C 1 89  ? -74.960  -15.709 27.128  1.00 59.69  ? 296 VAL C CB  1 
ATOM   3598  C CG1 . VAL C 1 89  ? -74.082  -14.479 27.299  1.00 51.80  ? 296 VAL C CG1 1 
ATOM   3599  C CG2 . VAL C 1 89  ? -76.416  -15.325 26.960  1.00 59.33  ? 296 VAL C CG2 1 
ATOM   3600  N N   . GLN C 1 90  ? -72.965  -15.515 24.499  1.00 53.00  ? 297 GLN C N   1 
ATOM   3601  C CA  . GLN C 1 90  ? -72.714  -14.726 23.271  1.00 55.89  ? 297 GLN C CA  1 
ATOM   3602  C C   . GLN C 1 90  ? -72.583  -15.700 22.098  1.00 55.06  ? 297 GLN C C   1 
ATOM   3603  O O   . GLN C 1 90  ? -73.018  -15.341 21.001  1.00 48.84  ? 297 GLN C O   1 
ATOM   3604  C CB  . GLN C 1 90  ? -71.496  -13.821 23.449  1.00 52.61  ? 297 GLN C CB  1 
ATOM   3605  C CG  . GLN C 1 90  ? -71.240  -12.894 22.271  1.00 50.40  ? 297 GLN C CG  1 
ATOM   3606  C CD  . GLN C 1 90  ? -70.204  -13.473 21.341  1.00 56.25  ? 297 GLN C CD  1 
ATOM   3607  O OE1 . GLN C 1 90  ? -69.606  -14.503 21.620  1.00 54.23  ? 297 GLN C OE1 1 
ATOM   3608  N NE2 . GLN C 1 90  ? -69.960  -12.800 20.233  1.00 57.67  ? 297 GLN C NE2 1 
ATOM   3609  N N   . GLU C 1 91  ? -72.065  -16.903 22.321  1.00 50.18  ? 298 GLU C N   1 
ATOM   3610  C CA  . GLU C 1 91  ? -71.993  -17.909 21.238  1.00 51.01  ? 298 GLU C CA  1 
ATOM   3611  C C   . GLU C 1 91  ? -73.406  -18.178 20.755  1.00 52.88  ? 298 GLU C C   1 
ATOM   3612  O O   . GLU C 1 91  ? -73.618  -18.225 19.546  1.00 47.50  ? 298 GLU C O   1 
ATOM   3613  C CB  . GLU C 1 91  ? -71.359  -19.208 21.725  1.00 53.07  ? 298 GLU C CB  1 
ATOM   3614  C CG  . GLU C 1 91  ? -71.169  -20.244 20.634  1.00 51.53  ? 298 GLU C CG  1 
ATOM   3615  C CD  . GLU C 1 91  ? -70.479  -21.522 21.069  1.00 55.76  ? 298 GLU C CD  1 
ATOM   3616  O OE1 . GLU C 1 91  ? -69.686  -22.058 20.279  1.00 58.87  ? 298 GLU C OE1 1 
ATOM   3617  O OE2 . GLU C 1 91  ? -70.741  -21.981 22.193  1.00 56.21  ? 298 GLU C OE2 1 
ATOM   3618  N N   . LEU C 1 92  ? -74.347  -18.383 21.669  1.00 52.77  ? 299 LEU C N   1 
ATOM   3619  C CA  . LEU C 1 92  ? -75.742  -18.670 21.268  1.00 50.35  ? 299 LEU C CA  1 
ATOM   3620  C C   . LEU C 1 92  ? -76.252  -17.491 20.452  1.00 54.78  ? 299 LEU C C   1 
ATOM   3621  O O   . LEU C 1 92  ? -76.749  -17.730 19.378  1.00 53.71  ? 299 LEU C O   1 
ATOM   3622  C CB  . LEU C 1 92  ? -76.618  -18.891 22.501  1.00 47.32  ? 299 LEU C CB  1 
ATOM   3623  C CG  . LEU C 1 92  ? -78.115  -19.018 22.233  1.00 48.68  ? 299 LEU C CG  1 
ATOM   3624  C CD1 . LEU C 1 92  ? -78.427  -20.288 21.462  1.00 51.23  ? 299 LEU C CD1 1 
ATOM   3625  C CD2 . LEU C 1 92  ? -78.888  -18.988 23.533  1.00 46.66  ? 299 LEU C CD2 1 
ATOM   3626  N N   . CYS C 1 93  ? -76.101  -16.273 20.955  1.00 56.84  ? 300 CYS C N   1 
ATOM   3627  C CA  . CYS C 1 93  ? -76.609  -15.061 20.254  1.00 55.44  ? 300 CYS C CA  1 
ATOM   3628  C C   . CYS C 1 93  ? -76.053  -14.991 18.839  1.00 51.16  ? 300 CYS C C   1 
ATOM   3629  O O   . CYS C 1 93  ? -76.820  -14.717 17.923  1.00 52.32  ? 300 CYS C O   1 
ATOM   3630  C CB  . CYS C 1 93  ? -76.176  -13.788 20.966  1.00 54.01  ? 300 CYS C CB  1 
ATOM   3631  S SG  . CYS C 1 93  ? -77.168  -12.331 20.568  1.00 54.78  ? 300 CYS C SG  1 
ATOM   3632  N N   . ARG C 1 94  ? -74.755  -15.233 18.691  1.00 49.13  ? 301 ARG C N   1 
ATOM   3633  C CA  . ARG C 1 94  ? -74.168  -15.204 17.332  1.00 48.76  ? 301 ARG C CA  1 
ATOM   3634  C C   . ARG C 1 94  ? -74.862  -16.242 16.459  1.00 57.20  ? 301 ARG C C   1 
ATOM   3635  O O   . ARG C 1 94  ? -75.182  -15.916 15.313  1.00 59.24  ? 301 ARG C O   1 
ATOM   3636  C CB  . ARG C 1 94  ? -72.664  -15.472 17.380  1.00 48.53  ? 301 ARG C CB  1 
ATOM   3637  C CG  . ARG C 1 94  ? -71.841  -14.328 17.951  1.00 55.74  ? 301 ARG C CG  1 
ATOM   3638  C CD  . ARG C 1 94  ? -71.653  -13.072 17.113  1.00 48.20  ? 301 ARG C CD  1 
ATOM   3639  N NE  . ARG C 1 94  ? -72.861  -12.368 16.703  1.00 47.39  ? 301 ARG C NE  1 
ATOM   3640  C CZ  . ARG C 1 94  ? -73.647  -11.642 17.490  1.00 53.13  ? 301 ARG C CZ  1 
ATOM   3641  N NH1 . ARG C 1 94  ? -73.367  -11.486 18.772  1.00 45.77  ? 301 ARG C NH1 1 
ATOM   3642  N NH2 . ARG C 1 94  ? -74.724  -11.073 16.988  1.00 59.06  ? 301 ARG C NH2 1 
ATOM   3643  N N   . VAL C 1 95  ? -75.085  -17.442 16.990  1.00 53.88  ? 302 VAL C N   1 
ATOM   3644  C CA  . VAL C 1 95  ? -75.696  -18.517 16.164  1.00 45.08  ? 302 VAL C CA  1 
ATOM   3645  C C   . VAL C 1 95  ? -77.202  -18.282 16.046  1.00 54.08  ? 302 VAL C C   1 
ATOM   3646  O O   . VAL C 1 95  ? -77.743  -18.530 14.964  1.00 54.22  ? 302 VAL C O   1 
ATOM   3647  C CB  . VAL C 1 95  ? -75.360  -19.897 16.763  1.00 54.13  ? 302 VAL C CB  1 
ATOM   3648  C CG1 . VAL C 1 95  ? -75.995  -21.038 15.990  1.00 65.98  ? 302 VAL C CG1 1 
ATOM   3649  C CG2 . VAL C 1 95  ? -73.860  -20.118 16.862  1.00 46.89  ? 302 VAL C CG2 1 
ATOM   3650  N N   . LEU C 1 96  ? -77.846  -17.756 17.086  1.00 52.96  ? 303 LEU C N   1 
ATOM   3651  C CA  . LEU C 1 96  ? -79.301  -17.653 17.047  1.00 52.88  ? 303 LEU C CA  1 
ATOM   3652  C C   . LEU C 1 96  ? -79.754  -16.545 16.091  1.00 54.26  ? 303 LEU C C   1 
ATOM   3653  O O   . LEU C 1 96  ? -80.653  -16.755 15.268  1.00 54.08  ? 303 LEU C O   1 
ATOM   3654  C CB  . LEU C 1 96  ? -79.840  -17.449 18.481  1.00 53.44  ? 303 LEU C CB  1 
ATOM   3655  C CG  . LEU C 1 96  ? -81.325  -17.532 18.904  1.00 50.27  ? 303 LEU C CG  1 
ATOM   3656  C CD1 . LEU C 1 96  ? -82.052  -16.237 18.730  1.00 45.86  ? 303 LEU C CD1 1 
ATOM   3657  C CD2 . LEU C 1 96  ? -82.056  -18.633 18.145  1.00 55.35  ? 303 LEU C CD2 1 
ATOM   3658  N N   . LEU C 1 97  ? -79.135  -15.376 16.190  1.00 53.42  ? 304 LEU C N   1 
ATOM   3659  C CA  . LEU C 1 97  ? -79.561  -14.226 15.356  1.00 47.34  ? 304 LEU C CA  1 
ATOM   3660  C C   . LEU C 1 97  ? -79.241  -14.499 13.888  1.00 52.67  ? 304 LEU C C   1 
ATOM   3661  O O   . LEU C 1 97  ? -80.015  -14.054 13.054  1.00 56.61  ? 304 LEU C O   1 
ATOM   3662  C CB  . LEU C 1 97  ? -78.864  -12.966 15.869  1.00 48.80  ? 304 LEU C CB  1 
ATOM   3663  C CG  . LEU C 1 97  ? -79.424  -12.370 17.155  1.00 54.82  ? 304 LEU C CG  1 
ATOM   3664  C CD1 . LEU C 1 97  ? -78.753  -11.043 17.453  1.00 52.00  ? 304 LEU C CD1 1 
ATOM   3665  C CD2 . LEU C 1 97  ? -80.928  -12.192 17.060  1.00 48.76  ? 304 LEU C CD2 1 
ATOM   3666  N N   . ASP C 1 98  ? -78.151  -15.203 13.587  1.00 49.81  ? 305 ASP C N   1 
ATOM   3667  C CA  . ASP C 1 98  ? -77.862  -15.577 12.212  1.00 50.06  ? 305 ASP C CA  1 
ATOM   3668  C C   . ASP C 1 98  ? -78.924  -16.532 11.666  1.00 54.78  ? 305 ASP C C   1 
ATOM   3669  O O   . ASP C 1 98  ? -79.411  -16.347 10.547  1.00 63.05  ? 305 ASP C O   1 
ATOM   3670  C CB  . ASP C 1 98  ? -76.460  -16.178 12.133  1.00 41.97  ? 305 ASP C CB  1 
ATOM   3671  C CG  . ASP C 1 98  ? -76.208  -16.884 10.829  1.00 48.93  ? 305 ASP C CG  1 
ATOM   3672  O OD1 . ASP C 1 98  ? -75.938  -16.209 9.811   1.00 49.52  ? 305 ASP C OD1 1 
ATOM   3673  O OD2 . ASP C 1 98  ? -76.289  -18.129 10.826  1.00 56.29  ? 305 ASP C OD2 1 
ATOM   3674  N N   . ASN C 1 99  ? -79.313  -17.543 12.447  1.00 50.84  ? 306 ASN C N   1 
ATOM   3675  C CA  . ASN C 1 99  ? -80.361  -18.465 12.011  1.00 56.27  ? 306 ASN C CA  1 
ATOM   3676  C C   . ASN C 1 99  ? -81.646  -17.724 11.659  1.00 58.09  ? 306 ASN C C   1 
ATOM   3677  O O   . ASN C 1 99  ? -82.248  -17.949 10.599  1.00 54.59  ? 306 ASN C O   1 
ATOM   3678  C CB  . ASN C 1 99  ? -80.639  -19.498 13.109  1.00 58.53  ? 306 ASN C CB  1 
ATOM   3679  C CG  . ASN C 1 99  ? -81.406  -20.715 12.594  1.00 62.68  ? 306 ASN C CG  1 
ATOM   3680  O OD1 . ASN C 1 99  ? -82.555  -20.619 12.160  1.00 70.33  ? 306 ASN C OD1 1 
ATOM   3681  N ND2 . ASN C 1 99  ? -80.768  -21.864 12.645  1.00 60.57  ? 306 ASN C ND2 1 
ATOM   3682  N N   . VAL C 1 100 ? -82.102  -16.864 12.568  1.00 57.38  ? 307 VAL C N   1 
ATOM   3683  C CA  . VAL C 1 100 ? -83.306  -16.080 12.324  1.00 60.44  ? 307 VAL C CA  1 
ATOM   3684  C C   . VAL C 1 100 ? -83.127  -15.197 11.097  1.00 62.51  ? 307 VAL C C   1 
ATOM   3685  O O   . VAL C 1 100 ? -84.012  -15.114 10.237  1.00 63.84  ? 307 VAL C O   1 
ATOM   3686  C CB  . VAL C 1 100 ? -83.646  -15.254 13.577  1.00 61.60  ? 307 VAL C CB  1 
ATOM   3687  C CG1 . VAL C 1 100 ? -84.864  -14.382 13.337  1.00 63.17  ? 307 VAL C CG1 1 
ATOM   3688  C CG2 . VAL C 1 100 ? -83.847  -16.167 14.764  1.00 61.09  ? 307 VAL C CG2 1 
ATOM   3689  N N   . GLU C 1 101 ? -81.968  -14.546 10.986  1.00 62.25  ? 308 GLU C N   1 
ATOM   3690  C CA  . GLU C 1 101 ? -81.756  -13.578 9.917   1.00 64.21  ? 308 GLU C CA  1 
ATOM   3691  C C   . GLU C 1 101 ? -81.978  -14.202 8.549   1.00 68.07  ? 308 GLU C C   1 
ATOM   3692  O O   . GLU C 1 101 ? -82.725  -13.654 7.726   1.00 67.88  ? 308 GLU C O   1 
ATOM   3693  C CB  . GLU C 1 101 ? -80.356  -12.987 10.010  1.00 65.86  ? 308 GLU C CB  1 
ATOM   3694  C CG  . GLU C 1 101 ? -80.207  -11.702 9.244   1.00 66.95  ? 308 GLU C CG  1 
ATOM   3695  C CD  . GLU C 1 101 ? -78.812  -11.126 9.378   1.00 71.45  ? 308 GLU C CD  1 
ATOM   3696  O OE1 . GLU C 1 101 ? -78.414  -10.344 8.484   1.00 78.70  ? 308 GLU C OE1 1 
ATOM   3697  O OE2 . GLU C 1 101 ? -78.115  -11.458 10.373  1.00 66.13  ? 308 GLU C OE2 1 
ATOM   3698  N N   . ASN C 1 102 ? -81.337  -15.346 8.279   1.00 64.69  ? 309 ASN C N   1 
ATOM   3699  C CA  . ASN C 1 102 ? -81.620  -16.055 7.036   1.00 63.64  ? 309 ASN C CA  1 
ATOM   3700  C C   . ASN C 1 102 ? -83.114  -16.294 6.905   1.00 66.77  ? 309 ASN C C   1 
ATOM   3701  O O   . ASN C 1 102 ? -83.767  -15.771 5.996   1.00 69.08  ? 309 ASN C O   1 
ATOM   3702  C CB  . ASN C 1 102 ? -80.870  -17.386 6.978   1.00 65.60  ? 309 ASN C CB  1 
ATOM   3703  C CG  . ASN C 1 102 ? -79.369  -17.214 6.883   1.00 75.49  ? 309 ASN C CG  1 
ATOM   3704  O OD1 . ASN C 1 102 ? -78.868  -16.147 6.520   1.00 79.52  ? 309 ASN C OD1 1 
ATOM   3705  N ND2 . ASN C 1 102 ? -78.636  -18.271 7.227   1.00 71.22  ? 309 ASN C ND2 1 
ATOM   3706  N N   . LYS C 1 103 ? -83.683  -17.029 7.864   1.00 63.53  ? 310 LYS C N   1 
ATOM   3707  C CA  . LYS C 1 103 ? -85.079  -17.423 7.775   1.00 57.83  ? 310 LYS C CA  1 
ATOM   3708  C C   . LYS C 1 103 ? -85.991  -16.224 7.603   1.00 61.47  ? 310 LYS C C   1 
ATOM   3709  O O   . LYS C 1 103 ? -87.135  -16.384 7.164   1.00 68.96  ? 310 LYS C O   1 
ATOM   3710  C CB  . LYS C 1 103 ? -85.476  -18.239 9.006   1.00 63.00  ? 310 LYS C CB  1 
ATOM   3711  C CG  . LYS C 1 103 ? -84.883  -19.657 9.009   1.00 62.00  ? 310 LYS C CG  1 
ATOM   3712  C CD  . LYS C 1 103 ? -85.598  -20.556 8.014   1.00 57.77  ? 310 LYS C CD  1 
ATOM   3713  C CE  . LYS C 1 103 ? -84.980  -21.942 7.922   1.00 64.74  ? 310 LYS C CE  1 
ATOM   3714  N NZ  . LYS C 1 103 ? -85.808  -22.907 7.091   1.00 73.36  ? 310 LYS C NZ  1 
ATOM   3715  N N   . MET C 1 104 ? -85.506  -15.026 7.899   1.00 57.45  ? 311 MET C N   1 
ATOM   3716  C CA  . MET C 1 104 ? -86.297  -13.847 7.604   1.00 62.75  ? 311 MET C CA  1 
ATOM   3717  C C   . MET C 1 104 ? -86.114  -13.369 6.168   1.00 65.14  ? 311 MET C C   1 
ATOM   3718  O O   . MET C 1 104 ? -86.877  -12.508 5.720   1.00 65.15  ? 311 MET C O   1 
ATOM   3719  C CB  . MET C 1 104 ? -85.953  -12.710 8.577   1.00 62.24  ? 311 MET C CB  1 
ATOM   3720  C CG  . MET C 1 104 ? -86.416  -12.888 10.011  1.00 53.32  ? 311 MET C CG  1 
ATOM   3721  S SD  . MET C 1 104 ? -86.376  -11.290 10.856  1.00 67.97  ? 311 MET C SD  1 
ATOM   3722  C CE  . MET C 1 104 ? -87.154  -11.621 12.437  1.00 46.98  ? 311 MET C CE  1 
ATOM   3723  N N   . LYS C 1 105 ? -85.121  -13.877 5.439   1.00 65.91  ? 312 LYS C N   1 
ATOM   3724  C CA  . LYS C 1 105 ? -84.928  -13.402 4.074   1.00 71.47  ? 312 LYS C CA  1 
ATOM   3725  C C   . LYS C 1 105 ? -86.048  -13.930 3.189   1.00 77.75  ? 312 LYS C C   1 
ATOM   3726  O O   . LYS C 1 105 ? -86.500  -15.071 3.345   1.00 75.32  ? 312 LYS C O   1 
ATOM   3727  C CB  . LYS C 1 105 ? -83.564  -13.815 3.516   1.00 64.25  ? 312 LYS C CB  1 
ATOM   3728  N N   . GLY C 1 106 ? -86.511  -13.076 2.274   1.00 71.21  ? 313 GLY C N   1 
ATOM   3729  C CA  . GLY C 1 106 ? -87.633  -13.425 1.434   1.00 69.57  ? 313 GLY C CA  1 
ATOM   3730  C C   . GLY C 1 106 ? -88.975  -13.219 2.087   1.00 78.04  ? 313 GLY C C   1 
ATOM   3731  O O   . GLY C 1 106 ? -89.966  -13.816 1.642   1.00 76.55  ? 313 GLY C O   1 
ATOM   3732  N N   . THR C 1 107 ? -88.979  -12.468 3.194   1.00 75.40  ? 314 THR C N   1 
ATOM   3733  C CA  . THR C 1 107 ? -90.224  -12.231 3.967   1.00 66.96  ? 314 THR C CA  1 
ATOM   3734  C C   . THR C 1 107 ? -90.482  -10.734 4.148   1.00 70.35  ? 314 THR C C   1 
ATOM   3735  O O   . THR C 1 107 ? -89.715  -9.924  3.602   1.00 70.13  ? 314 THR C O   1 
ATOM   3736  C CB  . THR C 1 107 ? -90.189  -12.918 5.339   1.00 65.46  ? 314 THR C CB  1 
ATOM   3737  O OG1 . THR C 1 107 ? -89.406  -12.145 6.249   1.00 66.34  ? 314 THR C OG1 1 
ATOM   3738  C CG2 . THR C 1 107 ? -89.678  -14.343 5.295   1.00 66.88  ? 314 THR C CG2 1 
ATOM   3739  N N   . CYS C 1 108 ? -91.526  -10.391 4.900   1.00 71.92  ? 315 CYS C N   1 
ATOM   3740  C CA  . CYS C 1 108 ? -91.924  -8.979  5.121   1.00 71.39  ? 315 CYS C CA  1 
ATOM   3741  C C   . CYS C 1 108 ? -90.974  -8.243  6.053   1.00 71.60  ? 315 CYS C C   1 
ATOM   3742  O O   . CYS C 1 108 ? -90.963  -7.006  6.010   1.00 75.45  ? 315 CYS C O   1 
ATOM   3743  C CB  . CYS C 1 108 ? -93.285  -8.970  5.799   1.00 75.35  ? 315 CYS C CB  1 
ATOM   3744  S SG  . CYS C 1 108 ? -93.534  -10.345 6.952   1.00 85.89  ? 315 CYS C SG  1 
ATOM   3745  N N   . VAL C 1 109 ? -90.236  -8.988  6.877   1.00 69.74  ? 316 VAL C N   1 
ATOM   3746  C CA  . VAL C 1 109 ? -89.377  -8.377  7.929   1.00 68.20  ? 316 VAL C CA  1 
ATOM   3747  C C   . VAL C 1 109 ? -87.901  -8.667  7.648   1.00 63.73  ? 316 VAL C C   1 
ATOM   3748  O O   . VAL C 1 109 ? -87.120  -8.727  8.604   1.00 59.80  ? 316 VAL C O   1 
ATOM   3749  C CB  . VAL C 1 109 ? -89.813  -8.918  9.302   1.00 64.39  ? 316 VAL C CB  1 
ATOM   3750  C CG1 . VAL C 1 109 ? -91.053  -8.202  9.810   1.00 66.29  ? 316 VAL C CG1 1 
ATOM   3751  C CG2 . VAL C 1 109 ? -90.047  -10.420 9.276   1.00 60.54  ? 316 VAL C CG2 1 
ATOM   3752  N N   . GLU C 1 110 ? -87.530  -8.798  6.378   1.00 63.31  ? 317 GLU C N   1 
ATOM   3753  C CA  . GLU C 1 110 ? -86.113  -9.020  6.018   1.00 64.11  ? 317 GLU C CA  1 
ATOM   3754  C C   . GLU C 1 110 ? -85.319  -7.769  6.372   1.00 63.51  ? 317 GLU C C   1 
ATOM   3755  O O   . GLU C 1 110 ? -85.718  -6.680  5.931   1.00 61.34  ? 317 GLU C O   1 
ATOM   3756  C CB  . GLU C 1 110 ? -86.008  -9.319  4.525   1.00 71.30  ? 317 GLU C CB  1 
ATOM   3757  C CG  . GLU C 1 110 ? -84.597  -9.569  4.034   1.00 68.83  ? 317 GLU C CG  1 
ATOM   3758  C CD  . GLU C 1 110 ? -84.512  -10.014 2.584   1.00 69.87  ? 317 GLU C CD  1 
ATOM   3759  O OE1 . GLU C 1 110 ? -83.399  -10.335 2.135   1.00 69.07  ? 317 GLU C OE1 1 
ATOM   3760  O OE2 . GLU C 1 110 ? -85.557  -10.047 1.912   1.00 70.18  ? 317 GLU C OE2 1 
ATOM   3761  N N   . GLY C 1 111 ? -84.256  -7.924  7.156   1.00 54.59  ? 318 GLY C N   1 
ATOM   3762  C CA  . GLY C 1 111 ? -83.381  -6.783  7.459   1.00 48.29  ? 318 GLY C CA  1 
ATOM   3763  C C   . GLY C 1 111 ? -83.589  -6.212  8.839   1.00 56.47  ? 318 GLY C C   1 
ATOM   3764  O O   . GLY C 1 111 ? -83.003  -5.177  9.102   1.00 57.86  ? 318 GLY C O   1 
ATOM   3765  N N   . THR C 1 112 ? -84.370  -6.874  9.688   1.00 60.44  ? 319 THR C N   1 
ATOM   3766  C CA  . THR C 1 112 ? -84.693  -6.328  11.030  1.00 47.07  ? 319 THR C CA  1 
ATOM   3767  C C   . THR C 1 112 ? -83.505  -6.580  11.954  1.00 49.14  ? 319 THR C C   1 
ATOM   3768  O O   . THR C 1 112 ? -83.096  -5.648  12.628  1.00 54.44  ? 319 THR C O   1 
ATOM   3769  C CB  . THR C 1 112 ? -86.019  -6.896  11.546  1.00 50.12  ? 319 THR C CB  1 
ATOM   3770  O OG1 . THR C 1 112 ? -87.005  -6.753  10.525  1.00 55.45  ? 319 THR C OG1 1 
ATOM   3771  C CG2 . THR C 1 112 ? -86.507  -6.196  12.794  1.00 51.01  ? 319 THR C CG2 1 
ATOM   3772  N N   . ILE C 1 113 ? -82.964  -7.792  11.954  1.00 49.01  ? 320 ILE C N   1 
ATOM   3773  C CA  . ILE C 1 113 ? -81.791  -8.088  12.754  1.00 53.83  ? 320 ILE C CA  1 
ATOM   3774  C C   . ILE C 1 113 ? -80.631  -7.172  12.382  1.00 52.29  ? 320 ILE C C   1 
ATOM   3775  O O   . ILE C 1 113 ? -80.035  -6.569  13.293  1.00 46.26  ? 320 ILE C O   1 
ATOM   3776  C CB  . ILE C 1 113 ? -81.458  -9.588  12.658  1.00 52.09  ? 320 ILE C CB  1 
ATOM   3777  C CG1 . ILE C 1 113 ? -82.408  -10.377 13.553  1.00 53.55  ? 320 ILE C CG1 1 
ATOM   3778  C CG2 . ILE C 1 113 ? -80.006  -9.849  13.009  1.00 51.88  ? 320 ILE C CG2 1 
ATOM   3779  C CD1 . ILE C 1 113 ? -82.471  -11.855 13.209  1.00 61.53  ? 320 ILE C CD1 1 
ATOM   3780  N N   . PRO C 1 114 ? -80.281  -6.980  11.095  1.00 54.49  ? 321 PRO C N   1 
ATOM   3781  C CA  . PRO C 1 114 ? -79.225  -6.002  10.806  1.00 51.49  ? 321 PRO C CA  1 
ATOM   3782  C C   . PRO C 1 114 ? -79.649  -4.576  11.097  1.00 45.11  ? 321 PRO C C   1 
ATOM   3783  O O   . PRO C 1 114 ? -78.839  -3.813  11.635  1.00 46.99  ? 321 PRO C O   1 
ATOM   3784  C CB  . PRO C 1 114 ? -78.882  -6.238  9.318   1.00 49.06  ? 321 PRO C CB  1 
ATOM   3785  C CG  . PRO C 1 114 ? -79.996  -7.009  8.756   1.00 51.93  ? 321 PRO C CG  1 
ATOM   3786  C CD  . PRO C 1 114 ? -80.636  -7.767  9.888   1.00 56.44  ? 321 PRO C CD  1 
ATOM   3787  N N   . LYS C 1 115 ? -80.893  -4.187  10.805  1.00 41.06  ? 322 LYS C N   1 
ATOM   3788  C CA  . LYS C 1 115 ? -81.275  -2.817  11.130  1.00 42.91  ? 322 LYS C CA  1 
ATOM   3789  C C   . LYS C 1 115 ? -81.089  -2.555  12.610  1.00 45.26  ? 322 LYS C C   1 
ATOM   3790  O O   . LYS C 1 115 ? -80.762  -1.435  13.009  1.00 48.25  ? 322 LYS C O   1 
ATOM   3791  C CB  . LYS C 1 115 ? -82.716  -2.514  10.702  1.00 36.59  ? 322 LYS C CB  1 
ATOM   3792  N N   . LEU C 1 116 ? -81.203  -3.594  13.429  1.00 53.03  ? 323 LEU C N   1 
ATOM   3793  C CA  . LEU C 1 116 ? -81.127  -3.455  14.878  1.00 54.65  ? 323 LEU C CA  1 
ATOM   3794  C C   . LEU C 1 116 ? -79.703  -3.548  15.424  1.00 51.97  ? 323 LEU C C   1 
ATOM   3795  O O   . LEU C 1 116 ? -79.322  -2.742  16.284  1.00 49.92  ? 323 LEU C O   1 
ATOM   3796  C CB  . LEU C 1 116 ? -82.010  -4.517  15.538  1.00 52.05  ? 323 LEU C CB  1 
ATOM   3797  C CG  . LEU C 1 116 ? -83.483  -4.127  15.600  1.00 51.74  ? 323 LEU C CG  1 
ATOM   3798  C CD1 . LEU C 1 116 ? -84.335  -5.312  15.933  1.00 50.39  ? 323 LEU C CD1 1 
ATOM   3799  C CD2 . LEU C 1 116 ? -83.661  -3.060  16.645  1.00 53.69  ? 323 LEU C CD2 1 
ATOM   3800  N N   . PHE C 1 117 ? -78.899  -4.499  14.932  1.00 47.85  ? 324 PHE C N   1 
ATOM   3801  C CA  . PHE C 1 117 ? -77.682  -4.894  15.626  1.00 49.23  ? 324 PHE C CA  1 
ATOM   3802  C C   . PHE C 1 117 ? -76.384  -4.613  14.876  1.00 48.49  ? 324 PHE C C   1 
ATOM   3803  O O   . PHE C 1 117 ? -75.311  -4.663  15.502  1.00 45.30  ? 324 PHE C O   1 
ATOM   3804  C CB  . PHE C 1 117 ? -77.717  -6.396  15.958  1.00 44.28  ? 324 PHE C CB  1 
ATOM   3805  C CG  . PHE C 1 117 ? -78.876  -6.824  16.838  1.00 50.16  ? 324 PHE C CG  1 
ATOM   3806  C CD1 . PHE C 1 117 ? -78.877  -6.571  18.202  1.00 54.99  ? 324 PHE C CD1 1 
ATOM   3807  C CD2 . PHE C 1 117 ? -79.943  -7.538  16.303  1.00 50.13  ? 324 PHE C CD2 1 
ATOM   3808  C CE1 . PHE C 1 117 ? -79.934  -7.011  19.009  1.00 51.29  ? 324 PHE C CE1 1 
ATOM   3809  C CE2 . PHE C 1 117 ? -81.003  -7.965  17.105  1.00 47.40  ? 324 PHE C CE2 1 
ATOM   3810  C CZ  . PHE C 1 117 ? -80.995  -7.704  18.448  1.00 45.61  ? 324 PHE C CZ  1 
ATOM   3811  N N   . ARG C 1 118 ? -76.428  -4.339  13.576  1.00 46.67  ? 325 ARG C N   1 
ATOM   3812  C CA  . ARG C 1 118 ? -75.213  -4.331  12.765  1.00 49.57  ? 325 ARG C CA  1 
ATOM   3813  C C   . ARG C 1 118 ? -74.691  -2.913  12.532  1.00 39.52  ? 325 ARG C C   1 
ATOM   3814  O O   . ARG C 1 118 ? -75.459  -2.012  12.191  1.00 46.58  ? 325 ARG C O   1 
ATOM   3815  C CB  . ARG C 1 118 ? -75.456  -5.045  11.434  1.00 49.63  ? 325 ARG C CB  1 
ATOM   3816  C CG  . ARG C 1 118 ? -74.275  -4.976  10.494  1.00 51.79  ? 325 ARG C CG  1 
ATOM   3817  C CD  . ARG C 1 118 ? -74.736  -4.401  9.177   1.00 52.25  ? 325 ARG C CD  1 
ATOM   3818  N NE  . ARG C 1 118 ? -75.061  -5.468  8.245   1.00 55.11  ? 325 ARG C NE  1 
ATOM   3819  C CZ  . ARG C 1 118 ? -75.832  -5.308  7.174   1.00 64.72  ? 325 ARG C CZ  1 
ATOM   3820  N NH1 . ARG C 1 118 ? -76.370  -4.111  6.898   1.00 47.79  ? 325 ARG C NH1 1 
ATOM   3821  N NH2 . ARG C 1 118 ? -76.056  -6.352  6.375   1.00 64.57  ? 325 ARG C NH2 1 
ATOM   3822  N N   . GLY C 1 119 ? -73.388  -2.730  12.755  1.00 41.84  ? 326 GLY C N   1 
ATOM   3823  C CA  . GLY C 1 119 ? -72.710  -1.481  12.479  1.00 44.44  ? 326 GLY C CA  1 
ATOM   3824  C C   . GLY C 1 119 ? -71.510  -1.719  11.578  1.00 48.15  ? 326 GLY C C   1 
ATOM   3825  O O   . GLY C 1 119 ? -71.295  -2.829  11.093  1.00 48.01  ? 326 GLY C O   1 
ATOM   3826  N N   . LYS C 1 120 ? -70.745  -0.645  11.349  1.00 46.74  ? 327 LYS C N   1 
ATOM   3827  C CA  . LYS C 1 120 ? -69.595  -0.692  10.454  1.00 44.85  ? 327 LYS C CA  1 
ATOM   3828  C C   . LYS C 1 120 ? -68.388  -0.045  11.103  1.00 47.24  ? 327 LYS C C   1 
ATOM   3829  O O   . LYS C 1 120 ? -68.489  1.069   11.636  1.00 44.57  ? 327 LYS C O   1 
ATOM   3830  C CB  . LYS C 1 120 ? -69.888  -0.002  9.132   1.00 45.62  ? 327 LYS C CB  1 
ATOM   3831  C CG  . LYS C 1 120 ? -68.932  -0.390  8.017   1.00 48.97  ? 327 LYS C CG  1 
ATOM   3832  C CD  . LYS C 1 120 ? -69.552  -1.419  7.063   1.00 49.82  ? 327 LYS C CD  1 
ATOM   3833  C CE  . LYS C 1 120 ? -70.806  -0.874  6.344   1.00 57.31  ? 327 LYS C CE  1 
ATOM   3834  N NZ  . LYS C 1 120 ? -71.696  -1.933  5.731   1.00 53.93  ? 327 LYS C NZ  1 
ATOM   3835  N N   . MET C 1 121 ? -67.261  -0.769  11.057  1.00 46.96  ? 328 MET C N   1 
ATOM   3836  C CA  . MET C 1 121 ? -65.918  -0.324  11.409  1.00 50.04  ? 328 MET C CA  1 
ATOM   3837  C C   . MET C 1 121 ? -65.109  0.039   10.165  1.00 49.04  ? 328 MET C C   1 
ATOM   3838  O O   . MET C 1 121 ? -65.321  -0.503  9.075   1.00 51.03  ? 328 MET C O   1 
ATOM   3839  C CB  . MET C 1 121 ? -65.145  -1.430  12.129  1.00 48.83  ? 328 MET C CB  1 
ATOM   3840  C CG  . MET C 1 121 ? -65.530  -1.765  13.533  1.00 52.57  ? 328 MET C CG  1 
ATOM   3841  S SD  . MET C 1 121 ? -64.643  -3.308  13.918  1.00 57.20  ? 328 MET C SD  1 
ATOM   3842  C CE  . MET C 1 121 ? -65.441  -4.418  12.784  1.00 38.43  ? 328 MET C CE  1 
ATOM   3843  N N   . VAL C 1 122 ? -64.110  0.891   10.349  1.00 43.59  ? 329 VAL C N   1 
ATOM   3844  C CA  . VAL C 1 122 ? -63.116  1.130   9.308   1.00 48.84  ? 329 VAL C CA  1 
ATOM   3845  C C   . VAL C 1 122 ? -61.735  0.829   9.881   1.00 51.09  ? 329 VAL C C   1 
ATOM   3846  O O   . VAL C 1 122 ? -61.405  1.282   10.983  1.00 50.83  ? 329 VAL C O   1 
ATOM   3847  C CB  . VAL C 1 122 ? -63.214  2.569   8.748   1.00 53.09  ? 329 VAL C CB  1 
ATOM   3848  C CG1 . VAL C 1 122 ? -63.234  3.642   9.861   1.00 52.59  ? 329 VAL C CG1 1 
ATOM   3849  C CG2 . VAL C 1 122 ? -62.098  2.835   7.733   1.00 55.96  ? 329 VAL C CG2 1 
ATOM   3850  N N   . SER C 1 123 ? -60.967  0.041   9.139   1.00 50.13  ? 330 SER C N   1 
ATOM   3851  C CA  . SER C 1 123 ? -59.579  -0.249  9.549   1.00 50.90  ? 330 SER C CA  1 
ATOM   3852  C C   . SER C 1 123 ? -58.628  0.437   8.577   1.00 53.93  ? 330 SER C C   1 
ATOM   3853  O O   . SER C 1 123 ? -58.811  0.286   7.371   1.00 57.12  ? 330 SER C O   1 
ATOM   3854  C CB  . SER C 1 123 ? -59.326  -1.715  9.625   1.00 54.12  ? 330 SER C CB  1 
ATOM   3855  O OG  . SER C 1 123 ? -58.293  -1.969  10.553  1.00 60.93  ? 330 SER C OG  1 
ATOM   3856  N N   . TYR C 1 124 ? -57.661  1.167   9.104   1.00 52.65  ? 331 TYR C N   1 
ATOM   3857  C CA  . TYR C 1 124 ? -56.687  1.897   8.300   1.00 53.01  ? 331 TYR C CA  1 
ATOM   3858  C C   . TYR C 1 124 ? -55.334  1.259   8.533   1.00 56.82  ? 331 TYR C C   1 
ATOM   3859  O O   . TYR C 1 124 ? -54.962  1.015   9.684   1.00 59.03  ? 331 TYR C O   1 
ATOM   3860  C CB  . TYR C 1 124 ? -56.601  3.380   8.688   1.00 52.26  ? 331 TYR C CB  1 
ATOM   3861  C CG  . TYR C 1 124 ? -57.893  4.193   8.701   1.00 63.23  ? 331 TYR C CG  1 
ATOM   3862  C CD1 . TYR C 1 124 ? -58.372  4.791   7.532   1.00 67.69  ? 331 TYR C CD1 1 
ATOM   3863  C CD2 . TYR C 1 124 ? -58.606  4.415   9.898   1.00 59.57  ? 331 TYR C CD2 1 
ATOM   3864  C CE1 . TYR C 1 124 ? -59.546  5.567   7.528   1.00 63.96  ? 331 TYR C CE1 1 
ATOM   3865  C CE2 . TYR C 1 124 ? -59.787  5.189   9.912   1.00 57.38  ? 331 TYR C CE2 1 
ATOM   3866  C CZ  . TYR C 1 124 ? -60.255  5.760   8.710   1.00 69.05  ? 331 TYR C CZ  1 
ATOM   3867  O OH  . TYR C 1 124 ? -61.417  6.530   8.661   1.00 62.86  ? 331 TYR C OH  1 
ATOM   3868  N N   . ILE C 1 125 ? -54.588  1.014   7.464   1.00 52.74  ? 332 ILE C N   1 
ATOM   3869  C CA  . ILE C 1 125 ? -53.226  0.509   7.591   1.00 53.18  ? 332 ILE C CA  1 
ATOM   3870  C C   . ILE C 1 125 ? -52.286  1.424   6.825   1.00 54.30  ? 332 ILE C C   1 
ATOM   3871  O O   . ILE C 1 125 ? -52.564  1.770   5.667   1.00 51.11  ? 332 ILE C O   1 
ATOM   3872  C CB  . ILE C 1 125 ? -53.112  -0.941  7.090   1.00 56.24  ? 332 ILE C CB  1 
ATOM   3873  C CG1 . ILE C 1 125 ? -53.879  -1.860  8.039   1.00 54.71  ? 332 ILE C CG1 1 
ATOM   3874  C CG2 . ILE C 1 125 ? -51.637  -1.374  6.954   1.00 49.94  ? 332 ILE C CG2 1 
ATOM   3875  C CD1 . ILE C 1 125 ? -54.361  -3.101  7.369   1.00 58.99  ? 332 ILE C CD1 1 
ATOM   3876  N N   . GLN C 1 126 ? -51.227  1.879   7.499   1.00 49.16  ? 333 GLN C N   1 
ATOM   3877  C CA  . GLN C 1 126 ? -50.226  2.780   6.878   1.00 55.28  ? 333 GLN C CA  1 
ATOM   3878  C C   . GLN C 1 126 ? -48.819  2.252   7.153   1.00 57.17  ? 333 GLN C C   1 
ATOM   3879  O O   . GLN C 1 126 ? -48.477  2.073   8.322   1.00 54.43  ? 333 GLN C O   1 
ATOM   3880  C CB  . GLN C 1 126 ? -50.362  4.195   7.439   1.00 56.74  ? 333 GLN C CB  1 
ATOM   3881  C CG  . GLN C 1 126 ? -49.214  5.132   7.099   1.00 56.33  ? 333 GLN C CG  1 
ATOM   3882  C CD  . GLN C 1 126 ? -49.327  5.719   5.715   1.00 70.55  ? 333 GLN C CD  1 
ATOM   3883  O OE1 . GLN C 1 126 ? -50.206  6.525   5.435   1.00 74.28  ? 333 GLN C OE1 1 
ATOM   3884  N NE2 . GLN C 1 126 ? -48.421  5.323   4.837   1.00 74.76  ? 333 GLN C NE2 1 
ATOM   3885  N N   . CYS C 1 127 ? -48.034  2.040   6.100   1.00 58.72  ? 334 CYS C N   1 
ATOM   3886  C CA  . CYS C 1 127 ? -46.635  1.576   6.254   1.00 57.18  ? 334 CYS C CA  1 
ATOM   3887  C C   . CYS C 1 127 ? -45.793  2.715   6.838   1.00 61.78  ? 334 CYS C C   1 
ATOM   3888  O O   . CYS C 1 127 ? -46.093  3.882   6.544   1.00 57.62  ? 334 CYS C O   1 
ATOM   3889  C CB  . CYS C 1 127 ? -46.114  1.043   4.927   1.00 53.75  ? 334 CYS C CB  1 
ATOM   3890  S SG  . CYS C 1 127 ? -46.968  -0.456  4.387   1.00 60.91  ? 334 CYS C SG  1 
ATOM   3891  N N   . LYS C 1 128 ? -44.754  2.385   7.605   1.00 64.14  ? 335 LYS C N   1 
ATOM   3892  C CA  . LYS C 1 128 ? -43.986  3.426   8.342   1.00 65.94  ? 335 LYS C CA  1 
ATOM   3893  C C   . LYS C 1 128 ? -42.740  3.907   7.594   1.00 62.26  ? 335 LYS C C   1 
ATOM   3894  O O   . LYS C 1 128 ? -42.311  5.035   7.866   1.00 62.67  ? 335 LYS C O   1 
ATOM   3895  C CB  . LYS C 1 128 ? -43.601  2.859   9.708   1.00 59.42  ? 335 LYS C CB  1 
ATOM   3896  C CG  . LYS C 1 128 ? -44.770  2.411   10.571  1.00 66.54  ? 335 LYS C CG  1 
ATOM   3897  C CD  . LYS C 1 128 ? -44.477  2.503   12.046  1.00 72.49  ? 335 LYS C CD  1 
ATOM   3898  C CE  . LYS C 1 128 ? -43.260  1.701   12.454  1.00 79.30  ? 335 LYS C CE  1 
ATOM   3899  N NZ  . LYS C 1 128 ? -42.370  2.476   13.349  1.00 79.18  ? 335 LYS C NZ  1 
ATOM   3900  N N   . GLU C 1 129 ? -42.172  3.088   6.715   1.00 66.35  ? 336 GLU C N   1 
ATOM   3901  C CA  . GLU C 1 129 ? -40.963  3.472   6.019   1.00 65.00  ? 336 GLU C CA  1 
ATOM   3902  C C   . GLU C 1 129 ? -41.181  3.582   4.527   1.00 68.37  ? 336 GLU C C   1 
ATOM   3903  O O   . GLU C 1 129 ? -40.290  4.062   3.816   1.00 74.72  ? 336 GLU C O   1 
ATOM   3904  C CB  . GLU C 1 129 ? -39.833  2.464   6.303   1.00 64.27  ? 336 GLU C CB  1 
ATOM   3905  C CG  . GLU C 1 129 ? -39.217  2.602   7.709   1.00 70.34  ? 336 GLU C CG  1 
ATOM   3906  C CD  . GLU C 1 129 ? -38.565  1.316   8.220   1.00 86.84  ? 336 GLU C CD  1 
ATOM   3907  O OE1 . GLU C 1 129 ? -37.494  1.414   8.873   1.00 83.98  ? 336 GLU C OE1 1 
ATOM   3908  O OE2 . GLU C 1 129 ? -39.124  0.214   7.976   1.00 88.25  ? 336 GLU C OE2 1 
ATOM   3909  N N   . VAL C 1 130 ? -42.351  3.174   4.047   1.00 64.77  ? 337 VAL C N   1 
ATOM   3910  C CA  . VAL C 1 130 ? -42.715  3.134   2.641   1.00 64.49  ? 337 VAL C CA  1 
ATOM   3911  C C   . VAL C 1 130 ? -44.038  3.892   2.486   1.00 65.37  ? 337 VAL C C   1 
ATOM   3912  O O   . VAL C 1 130 ? -44.756  4.126   3.461   1.00 65.93  ? 337 VAL C O   1 
ATOM   3913  C CB  . VAL C 1 130 ? -42.783  1.662   2.169   1.00 65.09  ? 337 VAL C CB  1 
ATOM   3914  C CG1 . VAL C 1 130 ? -43.723  1.449   1.006   1.00 64.92  ? 337 VAL C CG1 1 
ATOM   3915  C CG2 . VAL C 1 130 ? -41.383  1.191   1.831   1.00 56.30  ? 337 VAL C CG2 1 
ATOM   3916  N N   . ASP C 1 131 ? -44.323  4.377   1.274   1.00 63.76  ? 338 ASP C N   1 
ATOM   3917  C CA  . ASP C 1 131 ? -45.590  5.085   1.058   1.00 65.09  ? 338 ASP C CA  1 
ATOM   3918  C C   . ASP C 1 131 ? -46.620  4.091   0.533   1.00 68.56  ? 338 ASP C C   1 
ATOM   3919  O O   . ASP C 1 131 ? -46.838  3.939   -0.671  1.00 64.10  ? 338 ASP C O   1 
ATOM   3920  C CB  . ASP C 1 131 ? -45.434  6.280   0.129   1.00 64.62  ? 338 ASP C CB  1 
ATOM   3921  C CG  . ASP C 1 131 ? -46.783  6.908   -0.235  1.00 75.33  ? 338 ASP C CG  1 
ATOM   3922  O OD1 . ASP C 1 131 ? -47.741  6.790   0.577   1.00 78.08  ? 338 ASP C OD1 1 
ATOM   3923  O OD2 . ASP C 1 131 ? -46.890  7.515   -1.325  1.00 74.47  ? 338 ASP C OD2 1 
ATOM   3924  N N   . TYR C 1 132 ? -47.235  3.390   1.486   1.00 66.38  ? 339 TYR C N   1 
ATOM   3925  C CA  . TYR C 1 132 ? -48.300  2.418   1.155   1.00 57.38  ? 339 TYR C CA  1 
ATOM   3926  C C   . TYR C 1 132 ? -49.362  2.522   2.247   1.00 58.66  ? 339 TYR C C   1 
ATOM   3927  O O   . TYR C 1 132 ? -49.005  2.586   3.426   1.00 56.50  ? 339 TYR C O   1 
ATOM   3928  C CB  . TYR C 1 132 ? -47.725  1.010   1.014   1.00 55.64  ? 339 TYR C CB  1 
ATOM   3929  C CG  . TYR C 1 132 ? -48.553  0.032   0.225   1.00 52.91  ? 339 TYR C CG  1 
ATOM   3930  C CD1 . TYR C 1 132 ? -48.382  -0.102  -1.141  1.00 49.49  ? 339 TYR C CD1 1 
ATOM   3931  C CD2 . TYR C 1 132 ? -49.484  -0.782  0.845   1.00 50.88  ? 339 TYR C CD2 1 
ATOM   3932  C CE1 . TYR C 1 132 ? -49.128  -1.007  -1.874  1.00 48.67  ? 339 TYR C CE1 1 
ATOM   3933  C CE2 . TYR C 1 132 ? -50.240  -1.691  0.127   1.00 49.88  ? 339 TYR C CE2 1 
ATOM   3934  C CZ  . TYR C 1 132 ? -50.059  -1.805  -1.238  1.00 53.29  ? 339 TYR C CZ  1 
ATOM   3935  O OH  . TYR C 1 132 ? -50.796  -2.697  -1.958  1.00 53.48  ? 339 TYR C OH  1 
ATOM   3936  N N   . ARG C 1 133 ? -50.626  2.564   1.853   1.00 53.64  ? 340 ARG C N   1 
ATOM   3937  C CA  . ARG C 1 133 ? -51.748  2.675   2.771   1.00 49.84  ? 340 ARG C CA  1 
ATOM   3938  C C   . ARG C 1 133 ? -52.916  1.866   2.230   1.00 51.81  ? 340 ARG C C   1 
ATOM   3939  O O   . ARG C 1 133 ? -53.109  1.788   1.015   1.00 53.24  ? 340 ARG C O   1 
ATOM   3940  C CB  . ARG C 1 133 ? -52.155  4.136   2.965   1.00 53.90  ? 340 ARG C CB  1 
ATOM   3941  C CG  . ARG C 1 133 ? -53.147  4.363   4.091   1.00 59.36  ? 340 ARG C CG  1 
ATOM   3942  C CD  . ARG C 1 133 ? -53.337  5.844   4.339   1.00 60.02  ? 340 ARG C CD  1 
ATOM   3943  N NE  . ARG C 1 133 ? -54.533  6.126   5.127   1.00 65.85  ? 340 ARG C NE  1 
ATOM   3944  C CZ  . ARG C 1 133 ? -54.521  6.450   6.417   1.00 66.00  ? 340 ARG C CZ  1 
ATOM   3945  N NH1 . ARG C 1 133 ? -53.367  6.524   7.075   1.00 62.79  ? 340 ARG C NH1 1 
ATOM   3946  N NH2 . ARG C 1 133 ? -55.667  6.705   7.050   1.00 65.19  ? 340 ARG C NH2 1 
ATOM   3947  N N   . SER C 1 134 ? -53.666  1.244   3.133   1.00 53.88  ? 341 SER C N   1 
ATOM   3948  C CA  . SER C 1 134 ? -54.882  0.515   2.711   1.00 51.24  ? 341 SER C CA  1 
ATOM   3949  C C   . SER C 1 134 ? -56.017  0.753   3.701   1.00 49.57  ? 341 SER C C   1 
ATOM   3950  O O   . SER C 1 134 ? -55.740  1.135   4.838   1.00 51.08  ? 341 SER C O   1 
ATOM   3951  C CB  . SER C 1 134 ? -54.623  -0.937  2.518   1.00 51.63  ? 341 SER C CB  1 
ATOM   3952  O OG  . SER C 1 134 ? -55.414  -1.451  1.460   1.00 61.26  ? 341 SER C OG  1 
ATOM   3953  N N   . ASP C 1 135 ? -57.244  0.509   3.263   1.00 54.81  ? 342 ASP C N   1 
ATOM   3954  C CA  . ASP C 1 135 ? -58.458  0.761   4.078   1.00 51.50  ? 342 ASP C CA  1 
ATOM   3955  C C   . ASP C 1 135 ? -59.415  -0.432  3.942   1.00 51.10  ? 342 ASP C C   1 
ATOM   3956  O O   . ASP C 1 135 ? -59.401  -1.069  2.883   1.00 54.07  ? 342 ASP C O   1 
ATOM   3957  C CB  . ASP C 1 135 ? -59.156  2.035   3.599   1.00 47.35  ? 342 ASP C CB  1 
ATOM   3958  C CG  . ASP C 1 135 ? -58.731  3.329   4.260   1.00 51.10  ? 342 ASP C CG  1 
ATOM   3959  O OD1 . ASP C 1 135 ? -57.569  3.433   4.670   1.00 64.08  ? 342 ASP C OD1 1 
ATOM   3960  O OD2 . ASP C 1 135 ? -59.570  4.235   4.327   1.00 59.25  ? 342 ASP C OD2 1 
ATOM   3961  N N   . ARG C 1 136 ? -60.231  -0.708  4.963   1.00 45.16  ? 343 ARG C N   1 
ATOM   3962  C CA  . ARG C 1 136 ? -61.239  -1.798  4.891   1.00 48.57  ? 343 ARG C CA  1 
ATOM   3963  C C   . ARG C 1 136 ? -62.428  -1.493  5.800   1.00 49.78  ? 343 ARG C C   1 
ATOM   3964  O O   . ARG C 1 136 ? -62.213  -1.092  6.940   1.00 47.34  ? 343 ARG C O   1 
ATOM   3965  C CB  . ARG C 1 136 ? -60.632  -3.152  5.268   1.00 44.07  ? 343 ARG C CB  1 
ATOM   3966  C CG  . ARG C 1 136 ? -61.551  -4.343  5.046   1.00 46.19  ? 343 ARG C CG  1 
ATOM   3967  C CD  . ARG C 1 136 ? -61.989  -4.507  3.606   1.00 44.30  ? 343 ARG C CD  1 
ATOM   3968  N NE  . ARG C 1 136 ? -60.851  -4.618  2.708   1.00 54.99  ? 343 ARG C NE  1 
ATOM   3969  C CZ  . ARG C 1 136 ? -60.175  -5.734  2.485   1.00 54.04  ? 343 ARG C CZ  1 
ATOM   3970  N NH1 . ARG C 1 136 ? -60.526  -6.853  3.092   1.00 64.71  ? 343 ARG C NH1 1 
ATOM   3971  N NH2 . ARG C 1 136 ? -59.151  -5.728  1.653   1.00 48.59  ? 343 ARG C NH2 1 
ATOM   3972  N N   . ARG C 1 137 ? -63.634  -1.712  5.290   1.00 43.79  ? 344 ARG C N   1 
ATOM   3973  C CA  . ARG C 1 137 ? -64.869  -1.464  6.066   1.00 47.99  ? 344 ARG C CA  1 
ATOM   3974  C C   . ARG C 1 137 ? -65.610  -2.792  6.258   1.00 51.13  ? 344 ARG C C   1 
ATOM   3975  O O   . ARG C 1 137 ? -65.998  -3.382  5.241   1.00 51.23  ? 344 ARG C O   1 
ATOM   3976  C CB  . ARG C 1 137 ? -65.661  -0.375  5.345   1.00 45.62  ? 344 ARG C CB  1 
ATOM   3977  C CG  . ARG C 1 137 ? -65.085  1.018   5.526   1.00 42.98  ? 344 ARG C CG  1 
ATOM   3978  C CD  . ARG C 1 137 ? -65.196  1.836   4.261   1.00 42.61  ? 344 ARG C CD  1 
ATOM   3979  N NE  . ARG C 1 137 ? -64.455  3.074   4.416   1.00 40.60  ? 344 ARG C NE  1 
ATOM   3980  C CZ  . ARG C 1 137 ? -63.176  3.222   4.114   1.00 40.39  ? 344 ARG C CZ  1 
ATOM   3981  N NH1 . ARG C 1 137 ? -62.590  4.390   4.297   1.00 41.51  ? 344 ARG C NH1 1 
ATOM   3982  N NH2 . ARG C 1 137 ? -62.489  2.209   3.626   1.00 41.80  ? 344 ARG C NH2 1 
ATOM   3983  N N   . GLU C 1 138 ? -65.841  -3.216  7.508   1.00 50.13  ? 345 GLU C N   1 
ATOM   3984  C CA  . GLU C 1 138 ? -66.405  -4.524  7.817   1.00 49.52  ? 345 GLU C CA  1 
ATOM   3985  C C   . GLU C 1 138 ? -67.542  -4.401  8.824   1.00 50.22  ? 345 GLU C C   1 
ATOM   3986  O O   . GLU C 1 138 ? -67.389  -3.772  9.875   1.00 49.24  ? 345 GLU C O   1 
ATOM   3987  C CB  . GLU C 1 138 ? -65.324  -5.451  8.353   1.00 47.33  ? 345 GLU C CB  1 
ATOM   3988  C CG  . GLU C 1 138 ? -64.095  -5.506  7.487   1.00 45.43  ? 345 GLU C CG  1 
ATOM   3989  C CD  . GLU C 1 138 ? -63.039  -6.366  8.099   1.00 48.82  ? 345 GLU C CD  1 
ATOM   3990  O OE1 . GLU C 1 138 ? -62.812  -6.188  9.308   1.00 51.93  ? 345 GLU C OE1 1 
ATOM   3991  O OE2 . GLU C 1 138 ? -62.465  -7.232  7.398   1.00 52.42  ? 345 GLU C OE2 1 
ATOM   3992  N N   . ASP C 1 139 ? -68.681  -4.995  8.484   1.00 51.21  ? 346 ASP C N   1 
ATOM   3993  C CA  . ASP C 1 139 ? -69.805  -5.090  9.398   1.00 47.86  ? 346 ASP C CA  1 
ATOM   3994  C C   . ASP C 1 139 ? -69.388  -5.772  10.702  1.00 47.02  ? 346 ASP C C   1 
ATOM   3995  O O   . ASP C 1 139 ? -68.536  -6.661  10.720  1.00 51.05  ? 346 ASP C O   1 
ATOM   3996  C CB  . ASP C 1 139 ? -70.948  -5.880  8.732   1.00 49.76  ? 346 ASP C CB  1 
ATOM   3997  C CG  . ASP C 1 139 ? -71.551  -5.161  7.505   1.00 55.06  ? 346 ASP C CG  1 
ATOM   3998  O OD1 . ASP C 1 139 ? -71.406  -3.921  7.426   1.00 54.86  ? 346 ASP C OD1 1 
ATOM   3999  O OD2 . ASP C 1 139 ? -72.191  -5.829  6.634   1.00 46.92  ? 346 ASP C OD2 1 
ATOM   4000  N N   . TYR C 1 140 ? -69.994  -5.344  11.807  1.00 46.65  ? 347 TYR C N   1 
ATOM   4001  C CA  . TYR C 1 140 ? -70.048  -6.135  13.029  1.00 42.84  ? 347 TYR C CA  1 
ATOM   4002  C C   . TYR C 1 140 ? -71.490  -6.195  13.506  1.00 48.75  ? 347 TYR C C   1 
ATOM   4003  O O   . TYR C 1 140 ? -72.308  -5.326  13.187  1.00 45.94  ? 347 TYR C O   1 
ATOM   4004  C CB  . TYR C 1 140 ? -69.185  -5.551  14.150  1.00 39.71  ? 347 TYR C CB  1 
ATOM   4005  C CG  . TYR C 1 140 ? -69.609  -4.156  14.544  1.00 47.01  ? 347 TYR C CG  1 
ATOM   4006  C CD1 . TYR C 1 140 ? -69.129  -3.039  13.846  1.00 45.24  ? 347 TYR C CD1 1 
ATOM   4007  C CD2 . TYR C 1 140 ? -70.500  -3.950  15.579  1.00 37.24  ? 347 TYR C CD2 1 
ATOM   4008  C CE1 . TYR C 1 140 ? -69.497  -1.772  14.179  1.00 40.56  ? 347 TYR C CE1 1 
ATOM   4009  C CE2 . TYR C 1 140 ? -70.875  -2.677  15.929  1.00 43.37  ? 347 TYR C CE2 1 
ATOM   4010  C CZ  . TYR C 1 140 ? -70.374  -1.578  15.222  1.00 49.73  ? 347 TYR C CZ  1 
ATOM   4011  O OH  . TYR C 1 140 ? -70.752  -0.282  15.572  1.00 48.72  ? 347 TYR C OH  1 
ATOM   4012  N N   . TYR C 1 141 ? -71.774  -7.169  14.371  1.00 52.46  ? 348 TYR C N   1 
ATOM   4013  C CA  . TYR C 1 141 ? -73.109  -7.261  15.017  1.00 44.22  ? 348 TYR C CA  1 
ATOM   4014  C C   . TYR C 1 141 ? -72.908  -7.097  16.529  1.00 43.42  ? 348 TYR C C   1 
ATOM   4015  O O   . TYR C 1 141 ? -73.917  -6.968  17.230  1.00 44.44  ? 348 TYR C O   1 
ATOM   4016  C CB  . TYR C 1 141 ? -73.806  -8.566  14.636  1.00 48.46  ? 348 TYR C CB  1 
ATOM   4017  C CG  . TYR C 1 141 ? -74.506  -8.591  13.301  1.00 50.05  ? 348 TYR C CG  1 
ATOM   4018  C CD1 . TYR C 1 141 ? -73.793  -8.628  12.117  1.00 50.63  ? 348 TYR C CD1 1 
ATOM   4019  C CD2 . TYR C 1 141 ? -75.887  -8.617  13.221  1.00 54.33  ? 348 TYR C CD2 1 
ATOM   4020  C CE1 . TYR C 1 141 ? -74.424  -8.680  10.888  1.00 52.73  ? 348 TYR C CE1 1 
ATOM   4021  C CE2 . TYR C 1 141 ? -76.538  -8.661  12.001  1.00 56.67  ? 348 TYR C CE2 1 
ATOM   4022  C CZ  . TYR C 1 141 ? -75.804  -8.693  10.830  1.00 56.37  ? 348 TYR C CZ  1 
ATOM   4023  O OH  . TYR C 1 141 ? -76.426  -8.733  9.620   1.00 60.91  ? 348 TYR C OH  1 
ATOM   4024  N N   . ASP C 1 142 ? -71.656  -7.111  17.007  1.00 41.76  ? 349 ASP C N   1 
ATOM   4025  C CA  . ASP C 1 142 ? -71.337  -6.860  18.411  1.00 42.52  ? 349 ASP C CA  1 
ATOM   4026  C C   . ASP C 1 142 ? -69.885  -6.408  18.468  1.00 36.78  ? 349 ASP C C   1 
ATOM   4027  O O   . ASP C 1 142 ? -69.202  -6.362  17.452  1.00 42.81  ? 349 ASP C O   1 
ATOM   4028  C CB  . ASP C 1 142 ? -71.618  -8.092  19.301  1.00 41.61  ? 349 ASP C CB  1 
ATOM   4029  C CG  . ASP C 1 142 ? -70.724  -9.320  18.977  1.00 49.43  ? 349 ASP C CG  1 
ATOM   4030  O OD1 . ASP C 1 142 ? -69.925  -9.312  18.005  1.00 51.57  ? 349 ASP C OD1 1 
ATOM   4031  O OD2 . ASP C 1 142 ? -70.831  -10.324 19.709  1.00 48.22  ? 349 ASP C OD2 1 
ATOM   4032  N N   . ILE C 1 143 ? -69.441  -6.000  19.655  1.00 40.62  ? 350 ILE C N   1 
ATOM   4033  C CA  . ILE C 1 143 ? -68.056  -5.473  19.827  1.00 42.61  ? 350 ILE C CA  1 
ATOM   4034  C C   . ILE C 1 143 ? -67.349  -6.255  20.930  1.00 43.82  ? 350 ILE C C   1 
ATOM   4035  O O   . ILE C 1 143 ? -67.915  -6.379  22.010  1.00 44.07  ? 350 ILE C O   1 
ATOM   4036  C CB  . ILE C 1 143 ? -68.055  -3.960  20.143  1.00 41.71  ? 350 ILE C CB  1 
ATOM   4037  C CG1 . ILE C 1 143 ? -68.845  -3.142  19.122  1.00 34.11  ? 350 ILE C CG1 1 
ATOM   4038  C CG2 . ILE C 1 143 ? -66.638  -3.427  20.294  1.00 43.28  ? 350 ILE C CG2 1 
ATOM   4039  C CD1 . ILE C 1 143 ? -69.054  -1.715  19.538  1.00 37.77  ? 350 ILE C CD1 1 
ATOM   4040  N N   . GLN C 1 144 ? -66.147  -6.750  20.649  1.00 45.88  ? 351 GLN C N   1 
ATOM   4041  C CA  . GLN C 1 144 ? -65.332  -7.469  21.647  1.00 43.90  ? 351 GLN C CA  1 
ATOM   4042  C C   . GLN C 1 144 ? -64.452  -6.442  22.353  1.00 47.88  ? 351 GLN C C   1 
ATOM   4043  O O   . GLN C 1 144 ? -63.489  -5.981  21.738  1.00 52.64  ? 351 GLN C O   1 
ATOM   4044  C CB  . GLN C 1 144 ? -64.534  -8.549  20.923  1.00 40.16  ? 351 GLN C CB  1 
ATOM   4045  C CG  . GLN C 1 144 ? -65.359  -9.750  20.494  1.00 43.16  ? 351 GLN C CG  1 
ATOM   4046  C CD  . GLN C 1 144 ? -66.199  -9.530  19.262  1.00 43.45  ? 351 GLN C CD  1 
ATOM   4047  O OE1 . GLN C 1 144 ? -65.740  -9.010  18.252  1.00 49.51  ? 351 GLN C OE1 1 
ATOM   4048  N NE2 . GLN C 1 144 ? -67.457  -9.918  19.346  1.00 48.34  ? 351 GLN C NE2 1 
ATOM   4049  N N   . LEU C 1 145 ? -64.775  -6.104  23.597  1.00 42.51  ? 352 LEU C N   1 
ATOM   4050  C CA  . LEU C 1 145 ? -64.046  -5.106  24.370  1.00 44.57  ? 352 LEU C CA  1 
ATOM   4051  C C   . LEU C 1 145 ? -63.016  -5.776  25.258  1.00 46.84  ? 352 LEU C C   1 
ATOM   4052  O O   . LEU C 1 145 ? -63.329  -6.750  25.936  1.00 54.32  ? 352 LEU C O   1 
ATOM   4053  C CB  . LEU C 1 145 ? -64.986  -4.282  25.245  1.00 48.35  ? 352 LEU C CB  1 
ATOM   4054  C CG  . LEU C 1 145 ? -65.988  -3.316  24.652  1.00 40.58  ? 352 LEU C CG  1 
ATOM   4055  C CD1 . LEU C 1 145 ? -66.952  -2.915  25.759  1.00 39.28  ? 352 LEU C CD1 1 
ATOM   4056  C CD2 . LEU C 1 145 ? -65.222  -2.141  24.128  1.00 44.21  ? 352 LEU C CD2 1 
ATOM   4057  N N   . SER C 1 146 ? -61.806  -5.228  25.288  1.00 51.91  ? 353 SER C N   1 
ATOM   4058  C CA  . SER C 1 146 ? -60.745  -5.779  26.129  1.00 47.47  ? 353 SER C CA  1 
ATOM   4059  C C   . SER C 1 146 ? -60.878  -5.296  27.562  1.00 53.88  ? 353 SER C C   1 
ATOM   4060  O O   . SER C 1 146 ? -61.120  -4.111  27.823  1.00 56.09  ? 353 SER C O   1 
ATOM   4061  C CB  . SER C 1 146 ? -59.363  -5.387  25.604  1.00 47.41  ? 353 SER C CB  1 
ATOM   4062  O OG  . SER C 1 146 ? -58.822  -6.362  24.722  1.00 62.71  ? 353 SER C OG  1 
ATOM   4063  N N   . ILE C 1 147 ? -60.731  -6.228  28.515  1.00 61.26  ? 354 ILE C N   1 
ATOM   4064  C CA  . ILE C 1 147 ? -60.971  -5.930  29.964  1.00 59.57  ? 354 ILE C CA  1 
ATOM   4065  C C   . ILE C 1 147 ? -59.666  -5.814  30.758  1.00 60.80  ? 354 ILE C C   1 
ATOM   4066  O O   . ILE C 1 147 ? -59.535  -4.838  31.497  1.00 55.97  ? 354 ILE C O   1 
ATOM   4067  C CB  . ILE C 1 147 ? -61.855  -7.037  30.573  1.00 59.74  ? 354 ILE C CB  1 
ATOM   4068  C CG1 . ILE C 1 147 ? -63.146  -7.243  29.782  1.00 62.34  ? 354 ILE C CG1 1 
ATOM   4069  C CG2 . ILE C 1 147 ? -62.146  -6.780  32.043  1.00 64.04  ? 354 ILE C CG2 1 
ATOM   4070  C CD1 . ILE C 1 147 ? -63.920  -5.984  29.550  1.00 56.48  ? 354 ILE C CD1 1 
ATOM   4071  N N   . LYS C 1 148 ? -58.758  -6.776  30.630  1.00 61.45  ? 355 LYS C N   1 
ATOM   4072  C CA  . LYS C 1 148 ? -57.531  -6.779  31.468  1.00 59.53  ? 355 LYS C CA  1 
ATOM   4073  C C   . LYS C 1 148 ? -56.776  -5.460  31.320  1.00 58.89  ? 355 LYS C C   1 
ATOM   4074  O O   . LYS C 1 148 ? -56.538  -5.041  30.183  1.00 63.92  ? 355 LYS C O   1 
ATOM   4075  C CB  . LYS C 1 148 ? -56.639  -7.967  31.108  1.00 57.16  ? 355 LYS C CB  1 
ATOM   4076  C CG  . LYS C 1 148 ? -55.663  -8.404  32.189  1.00 63.31  ? 355 LYS C CG  1 
ATOM   4077  C CD  . LYS C 1 148 ? -56.347  -8.959  33.414  1.00 59.10  ? 355 LYS C CD  1 
ATOM   4078  C CE  . LYS C 1 148 ? -55.415  -9.101  34.597  1.00 57.88  ? 355 LYS C CE  1 
ATOM   4079  N NZ  . LYS C 1 148 ? -56.030  -9.903  35.678  1.00 62.75  ? 355 LYS C NZ  1 
ATOM   4080  N N   . GLY C 1 149 ? -56.387  -4.865  32.445  1.00 56.74  ? 356 GLY C N   1 
ATOM   4081  C CA  . GLY C 1 149 ? -55.635  -3.598  32.412  1.00 55.44  ? 356 GLY C CA  1 
ATOM   4082  C C   . GLY C 1 149 ? -56.513  -2.377  32.249  1.00 53.49  ? 356 GLY C C   1 
ATOM   4083  O O   . GLY C 1 149 ? -55.974  -1.266  32.276  1.00 49.54  ? 356 GLY C O   1 
ATOM   4084  N N   . LYS C 1 150 ? -57.817  -2.574  32.085  1.00 50.41  ? 357 LYS C N   1 
ATOM   4085  C CA  . LYS C 1 150 ? -58.705  -1.444  31.855  1.00 56.80  ? 357 LYS C CA  1 
ATOM   4086  C C   . LYS C 1 150 ? -59.639  -1.322  33.046  1.00 58.43  ? 357 LYS C C   1 
ATOM   4087  O O   . LYS C 1 150 ? -60.351  -2.274  33.378  1.00 58.34  ? 357 LYS C O   1 
ATOM   4088  C CB  . LYS C 1 150 ? -59.494  -1.609  30.550  1.00 58.51  ? 357 LYS C CB  1 
ATOM   4089  C CG  . LYS C 1 150 ? -58.720  -2.295  29.425  1.00 59.09  ? 357 LYS C CG  1 
ATOM   4090  C CD  . LYS C 1 150 ? -57.658  -1.379  28.820  1.00 58.02  ? 357 LYS C CD  1 
ATOM   4091  C CE  . LYS C 1 150 ? -56.471  -2.158  28.267  1.00 57.92  ? 357 LYS C CE  1 
ATOM   4092  N NZ  . LYS C 1 150 ? -56.896  -3.460  27.654  1.00 68.12  ? 357 LYS C NZ  1 
ATOM   4093  N N   . LYS C 1 151 ? -59.622  -0.162  33.701  1.00 58.75  ? 358 LYS C N   1 
ATOM   4094  C CA  . LYS C 1 151 ? -60.482  -0.006  34.861  1.00 55.65  ? 358 LYS C CA  1 
ATOM   4095  C C   . LYS C 1 151 ? -61.937  0.161   34.432  1.00 59.59  ? 358 LYS C C   1 
ATOM   4096  O O   . LYS C 1 151 ? -62.840  -0.404  35.062  1.00 63.82  ? 358 LYS C O   1 
ATOM   4097  C CB  . LYS C 1 151 ? -60.004  1.164   35.722  1.00 48.04  ? 358 LYS C CB  1 
ATOM   4098  N N   . ASN C 1 152 ? -62.192  0.883   33.342  1.00 56.10  ? 359 ASN C N   1 
ATOM   4099  C CA  . ASN C 1 152 ? -63.564  1.167   32.946  1.00 59.27  ? 359 ASN C CA  1 
ATOM   4100  C C   . ASN C 1 152 ? -63.740  0.953   31.443  1.00 56.19  ? 359 ASN C C   1 
ATOM   4101  O O   . ASN C 1 152 ? -62.793  0.657   30.711  1.00 53.74  ? 359 ASN C O   1 
ATOM   4102  C CB  . ASN C 1 152 ? -63.956  2.591   33.350  1.00 62.61  ? 359 ASN C CB  1 
ATOM   4103  C CG  . ASN C 1 152 ? -63.078  3.640   32.703  1.00 55.89  ? 359 ASN C CG  1 
ATOM   4104  O OD1 . ASN C 1 152 ? -63.131  3.842   31.490  1.00 55.16  ? 359 ASN C OD1 1 
ATOM   4105  N ND2 . ASN C 1 152 ? -62.267  4.315   33.507  1.00 54.99  ? 359 ASN C ND2 1 
ATOM   4106  N N   . ILE C 1 153 ? -64.983  1.102   30.972  1.00 54.65  ? 360 ILE C N   1 
ATOM   4107  C CA  . ILE C 1 153 ? -65.339  0.833   29.544  1.00 52.40  ? 360 ILE C CA  1 
ATOM   4108  C C   . ILE C 1 153 ? -64.776  1.902   28.613  1.00 53.27  ? 360 ILE C C   1 
ATOM   4109  O O   . ILE C 1 153 ? -64.484  1.579   27.467  1.00 51.93  ? 360 ILE C O   1 
ATOM   4110  C CB  . ILE C 1 153 ? -66.871  0.694   29.422  1.00 50.00  ? 360 ILE C CB  1 
ATOM   4111  C CG1 . ILE C 1 153 ? -67.296  -0.081  28.176  1.00 47.44  ? 360 ILE C CG1 1 
ATOM   4112  C CG2 . ILE C 1 153 ? -67.576  2.037   29.510  1.00 52.21  ? 360 ILE C CG2 1 
ATOM   4113  C CD1 . ILE C 1 153 ? -68.757  -0.417  28.178  1.00 46.26  ? 360 ILE C CD1 1 
ATOM   4114  N N   . PHE C 1 154 ? -64.618  3.125   29.092  1.00 53.26  ? 361 PHE C N   1 
ATOM   4115  C CA  . PHE C 1 154 ? -64.001  4.175   28.257  1.00 51.29  ? 361 PHE C CA  1 
ATOM   4116  C C   . PHE C 1 154 ? -62.546  3.795   28.026  1.00 58.12  ? 361 PHE C C   1 
ATOM   4117  O O   . PHE C 1 154 ? -62.117  3.873   26.882  1.00 56.99  ? 361 PHE C O   1 
ATOM   4118  C CB  . PHE C 1 154 ? -64.179  5.532   28.923  1.00 47.70  ? 361 PHE C CB  1 
ATOM   4119  C CG  . PHE C 1 154 ? -65.609  5.980   29.003  1.00 51.96  ? 361 PHE C CG  1 
ATOM   4120  C CD1 . PHE C 1 154 ? -66.202  6.626   27.935  1.00 48.93  ? 361 PHE C CD1 1 
ATOM   4121  C CD2 . PHE C 1 154 ? -66.362  5.740   30.138  1.00 53.51  ? 361 PHE C CD2 1 
ATOM   4122  C CE1 . PHE C 1 154 ? -67.521  7.034   28.007  1.00 48.26  ? 361 PHE C CE1 1 
ATOM   4123  C CE2 . PHE C 1 154 ? -67.681  6.147   30.205  1.00 54.95  ? 361 PHE C CE2 1 
ATOM   4124  C CZ  . PHE C 1 154 ? -68.254  6.795   29.143  1.00 49.99  ? 361 PHE C CZ  1 
ATOM   4125  N N   . GLU C 1 155 ? -61.829  3.372   29.070  1.00 56.66  ? 362 GLU C N   1 
ATOM   4126  C CA  . GLU C 1 155 ? -60.474  2.895   28.818  1.00 52.97  ? 362 GLU C CA  1 
ATOM   4127  C C   . GLU C 1 155 ? -60.492  1.757   27.816  1.00 54.80  ? 362 GLU C C   1 
ATOM   4128  O O   . GLU C 1 155 ? -59.563  1.620   27.012  1.00 60.43  ? 362 GLU C O   1 
ATOM   4129  C CB  . GLU C 1 155 ? -59.798  2.464   30.118  1.00 56.34  ? 362 GLU C CB  1 
ATOM   4130  C CG  . GLU C 1 155 ? -59.277  3.654   30.926  1.00 66.04  ? 362 GLU C CG  1 
ATOM   4131  C CD  . GLU C 1 155 ? -58.490  3.259   32.168  1.00 62.83  ? 362 GLU C CD  1 
ATOM   4132  O OE1 . GLU C 1 155 ? -57.721  2.274   32.104  1.00 63.24  ? 362 GLU C OE1 1 
ATOM   4133  O OE2 . GLU C 1 155 ? -58.641  3.958   33.200  1.00 58.64  ? 362 GLU C OE2 1 
ATOM   4134  N N   . SER C 1 156 ? -61.573  0.973   27.794  1.00 53.84  ? 363 SER C N   1 
ATOM   4135  C CA  . SER C 1 156 ? -61.609  -0.133  26.854  1.00 55.66  ? 363 SER C CA  1 
ATOM   4136  C C   . SER C 1 156 ? -61.793  0.371   25.432  1.00 52.43  ? 363 SER C C   1 
ATOM   4137  O O   . SER C 1 156 ? -61.113  -0.101  24.513  1.00 54.97  ? 363 SER C O   1 
ATOM   4138  C CB  . SER C 1 156 ? -62.702  -1.134  27.245  1.00 54.30  ? 363 SER C CB  1 
ATOM   4139  O OG  . SER C 1 156 ? -62.661  -2.243  26.355  1.00 54.79  ? 363 SER C OG  1 
ATOM   4140  N N   . PHE C 1 157 ? -62.680  1.342   25.237  1.00 49.95  ? 364 PHE C N   1 
ATOM   4141  C CA  . PHE C 1 157 ? -62.899  1.857   23.892  1.00 45.34  ? 364 PHE C CA  1 
ATOM   4142  C C   . PHE C 1 157 ? -61.667  2.594   23.383  1.00 48.39  ? 364 PHE C C   1 
ATOM   4143  O O   . PHE C 1 157 ? -61.284  2.448   22.213  1.00 49.57  ? 364 PHE C O   1 
ATOM   4144  C CB  . PHE C 1 157 ? -64.125  2.762   23.865  1.00 43.02  ? 364 PHE C CB  1 
ATOM   4145  C CG  . PHE C 1 157 ? -65.432  2.028   23.647  1.00 47.43  ? 364 PHE C CG  1 
ATOM   4146  C CD1 . PHE C 1 157 ? -65.834  1.678   22.370  1.00 45.21  ? 364 PHE C CD1 1 
ATOM   4147  C CD2 . PHE C 1 157 ? -66.272  1.705   24.726  1.00 48.91  ? 364 PHE C CD2 1 
ATOM   4148  C CE1 . PHE C 1 157 ? -67.056  1.012   22.152  1.00 48.16  ? 364 PHE C CE1 1 
ATOM   4149  C CE2 . PHE C 1 157 ? -67.490  1.040   24.530  1.00 44.39  ? 364 PHE C CE2 1 
ATOM   4150  C CZ  . PHE C 1 157 ? -67.883  0.689   23.235  1.00 48.81  ? 364 PHE C CZ  1 
ATOM   4151  N N   . VAL C 1 158 ? -61.023  3.378   24.250  1.00 49.32  ? 365 VAL C N   1 
ATOM   4152  C CA  . VAL C 1 158 ? -59.810  4.077   23.842  1.00 44.86  ? 365 VAL C CA  1 
ATOM   4153  C C   . VAL C 1 158 ? -58.772  3.071   23.381  1.00 47.18  ? 365 VAL C C   1 
ATOM   4154  O O   . VAL C 1 158 ? -58.077  3.275   22.378  1.00 47.66  ? 365 VAL C O   1 
ATOM   4155  C CB  . VAL C 1 158 ? -59.270  4.953   24.988  1.00 47.37  ? 365 VAL C CB  1 
ATOM   4156  C CG1 . VAL C 1 158 ? -57.924  5.572   24.592  1.00 39.62  ? 365 VAL C CG1 1 
ATOM   4157  C CG2 . VAL C 1 158 ? -60.285  6.020   25.398  1.00 42.16  ? 365 VAL C CG2 1 
ATOM   4158  N N   . ASP C 1 159 ? -58.669  1.955   24.083  1.00 44.84  ? 366 ASP C N   1 
ATOM   4159  C CA  . ASP C 1 159 ? -57.785  0.921   23.596  1.00 43.19  ? 366 ASP C CA  1 
ATOM   4160  C C   . ASP C 1 159 ? -58.288  0.370   22.276  1.00 43.60  ? 366 ASP C C   1 
ATOM   4161  O O   . ASP C 1 159 ? -57.492  0.112   21.367  1.00 42.89  ? 366 ASP C O   1 
ATOM   4162  C CB  . ASP C 1 159 ? -57.653  -0.175  24.641  1.00 52.40  ? 366 ASP C CB  1 
ATOM   4163  C CG  . ASP C 1 159 ? -56.445  -1.045  24.397  1.00 63.20  ? 366 ASP C CG  1 
ATOM   4164  O OD1 . ASP C 1 159 ? -55.353  -0.442  24.201  1.00 55.15  ? 366 ASP C OD1 1 
ATOM   4165  O OD2 . ASP C 1 159 ? -56.595  -2.302  24.376  1.00 58.63  ? 366 ASP C OD2 1 
ATOM   4166  N N   . TYR C 1 160 ? -59.613  0.234   22.131  1.00 45.19  ? 367 TYR C N   1 
ATOM   4167  C CA  . TYR C 1 160 ? -60.148  -0.378  20.917  1.00 46.33  ? 367 TYR C CA  1 
ATOM   4168  C C   . TYR C 1 160 ? -59.721  0.382   19.680  1.00 44.31  ? 367 TYR C C   1 
ATOM   4169  O O   . TYR C 1 160 ? -59.384  -0.225  18.661  1.00 49.21  ? 367 TYR C O   1 
ATOM   4170  C CB  . TYR C 1 160 ? -61.672  -0.483  20.945  1.00 42.80  ? 367 TYR C CB  1 
ATOM   4171  C CG  . TYR C 1 160 ? -62.181  -1.520  19.945  1.00 45.31  ? 367 TYR C CG  1 
ATOM   4172  C CD1 . TYR C 1 160 ? -62.194  -2.876  20.256  1.00 44.87  ? 367 TYR C CD1 1 
ATOM   4173  C CD2 . TYR C 1 160 ? -62.618  -1.147  18.685  1.00 47.91  ? 367 TYR C CD2 1 
ATOM   4174  C CE1 . TYR C 1 160 ? -62.645  -3.816  19.346  1.00 46.67  ? 367 TYR C CE1 1 
ATOM   4175  C CE2 . TYR C 1 160 ? -63.076  -2.089  17.772  1.00 45.11  ? 367 TYR C CE2 1 
ATOM   4176  C CZ  . TYR C 1 160 ? -63.077  -3.417  18.108  1.00 47.59  ? 367 TYR C CZ  1 
ATOM   4177  O OH  . TYR C 1 160 ? -63.517  -4.353  17.203  1.00 52.44  ? 367 TYR C OH  1 
ATOM   4178  N N   . VAL C 1 161 ? -59.698  1.709   19.763  1.00 45.42  ? 368 VAL C N   1 
ATOM   4179  C CA  . VAL C 1 161 ? -59.386  2.563   18.631  1.00 45.74  ? 368 VAL C CA  1 
ATOM   4180  C C   . VAL C 1 161 ? -57.961  3.098   18.691  1.00 46.13  ? 368 VAL C C   1 
ATOM   4181  O O   . VAL C 1 161 ? -57.577  3.914   17.858  1.00 46.06  ? 368 VAL C O   1 
ATOM   4182  C CB  . VAL C 1 161 ? -60.401  3.701   18.540  1.00 46.03  ? 368 VAL C CB  1 
ATOM   4183  C CG1 . VAL C 1 161 ? -61.783  3.118   18.580  1.00 48.50  ? 368 VAL C CG1 1 
ATOM   4184  C CG2 . VAL C 1 161 ? -60.222  4.646   19.691  1.00 42.93  ? 368 VAL C CG2 1 
ATOM   4185  N N   . ALA C 1 162 ? -57.164  2.644   19.647  1.00 45.91  ? 369 ALA C N   1 
ATOM   4186  C CA  . ALA C 1 162 ? -55.778  3.074   19.703  1.00 45.96  ? 369 ALA C CA  1 
ATOM   4187  C C   . ALA C 1 162 ? -54.997  2.527   18.518  1.00 50.54  ? 369 ALA C C   1 
ATOM   4188  O O   . ALA C 1 162 ? -55.379  1.530   17.897  1.00 56.20  ? 369 ALA C O   1 
ATOM   4189  C CB  . ALA C 1 162 ? -55.130  2.619   21.006  1.00 51.71  ? 369 ALA C CB  1 
ATOM   4190  N N   . VAL C 1 163 ? -53.880  3.188   18.208  1.00 50.95  ? 370 VAL C N   1 
ATOM   4191  C CA  . VAL C 1 163 ? -53.056  2.821   17.059  1.00 49.16  ? 370 VAL C CA  1 
ATOM   4192  C C   . VAL C 1 163 ? -52.049  1.751   17.470  1.00 49.70  ? 370 VAL C C   1 
ATOM   4193  O O   . VAL C 1 163 ? -51.545  1.736   18.600  1.00 53.55  ? 370 VAL C O   1 
ATOM   4194  C CB  . VAL C 1 163 ? -52.356  4.061   16.475  1.00 47.32  ? 370 VAL C CB  1 
ATOM   4195  C CG1 . VAL C 1 163 ? -51.560  3.703   15.200  1.00 46.60  ? 370 VAL C CG1 1 
ATOM   4196  C CG2 . VAL C 1 163 ? -53.379  5.101   16.169  1.00 46.13  ? 370 VAL C CG2 1 
ATOM   4197  N N   . GLU C 1 164 ? -51.751  0.858   16.538  1.00 49.41  ? 371 GLU C N   1 
ATOM   4198  C CA  . GLU C 1 164 ? -51.075  -0.406  16.779  1.00 44.45  ? 371 GLU C CA  1 
ATOM   4199  C C   . GLU C 1 164 ? -49.878  -0.539  15.844  1.00 56.08  ? 371 GLU C C   1 
ATOM   4200  O O   . GLU C 1 164 ? -49.947  -0.170  14.661  1.00 50.43  ? 371 GLU C O   1 
ATOM   4201  C CB  . GLU C 1 164 ? -52.026  -1.559  16.518  1.00 45.24  ? 371 GLU C CB  1 
ATOM   4202  C CG  . GLU C 1 164 ? -52.321  -2.515  17.639  1.00 51.84  ? 371 GLU C CG  1 
ATOM   4203  C CD  . GLU C 1 164 ? -53.041  -3.742  17.088  1.00 56.89  ? 371 GLU C CD  1 
ATOM   4204  O OE1 . GLU C 1 164 ? -52.612  -4.880  17.344  1.00 62.46  ? 371 GLU C OE1 1 
ATOM   4205  O OE2 . GLU C 1 164 ? -54.016  -3.556  16.340  1.00 54.22  ? 371 GLU C OE2 1 
ATOM   4206  N N   . GLN C 1 165 ? -48.797  -1.110  16.361  1.00 54.40  ? 372 GLN C N   1 
ATOM   4207  C CA  . GLN C 1 165 ? -47.630  -1.385  15.548  1.00 53.33  ? 372 GLN C CA  1 
ATOM   4208  C C   . GLN C 1 165 ? -47.685  -2.805  15.016  1.00 54.56  ? 372 GLN C C   1 
ATOM   4209  O O   . GLN C 1 165 ? -47.876  -3.757  15.780  1.00 58.22  ? 372 GLN C O   1 
ATOM   4210  C CB  . GLN C 1 165 ? -46.356  -1.172  16.346  1.00 53.26  ? 372 GLN C CB  1 
ATOM   4211  C CG  . GLN C 1 165 ? -46.325  0.174   16.964  1.00 45.85  ? 372 GLN C CG  1 
ATOM   4212  C CD  . GLN C 1 165 ? -46.308  1.231   15.929  1.00 55.34  ? 372 GLN C CD  1 
ATOM   4213  O OE1 . GLN C 1 165 ? -45.884  0.992   14.800  1.00 65.00  ? 372 GLN C OE1 1 
ATOM   4214  N NE2 . GLN C 1 165 ? -46.755  2.422   16.291  1.00 62.69  ? 372 GLN C NE2 1 
ATOM   4215  N N   . LEU C 1 166 ? -47.536  -2.928  13.704  1.00 53.35  ? 373 LEU C N   1 
ATOM   4216  C CA  . LEU C 1 166 ? -47.387  -4.207  13.029  1.00 51.80  ? 373 LEU C CA  1 
ATOM   4217  C C   . LEU C 1 166 ? -45.895  -4.361  12.754  1.00 58.86  ? 373 LEU C C   1 
ATOM   4218  O O   . LEU C 1 166 ? -45.336  -3.695  11.877  1.00 59.88  ? 373 LEU C O   1 
ATOM   4219  C CB  . LEU C 1 166 ? -48.222  -4.247  11.757  1.00 54.31  ? 373 LEU C CB  1 
ATOM   4220  C CG  . LEU C 1 166 ? -49.731  -4.205  11.996  1.00 52.58  ? 373 LEU C CG  1 
ATOM   4221  C CD1 . LEU C 1 166 ? -50.471  -4.270  10.680  1.00 49.84  ? 373 LEU C CD1 1 
ATOM   4222  C CD2 . LEU C 1 166 ? -50.155  -5.332  12.909  1.00 44.61  ? 373 LEU C CD2 1 
ATOM   4223  N N   . ASP C 1 167 ? -45.244  -5.215  13.539  1.00 60.70  ? 374 ASP C N   1 
ATOM   4224  C CA  . ASP C 1 167 ? -43.802  -5.363  13.519  1.00 57.29  ? 374 ASP C CA  1 
ATOM   4225  C C   . ASP C 1 167 ? -43.458  -6.842  13.580  1.00 61.69  ? 374 ASP C C   1 
ATOM   4226  O O   . ASP C 1 167 ? -44.331  -7.703  13.752  1.00 59.31  ? 374 ASP C O   1 
ATOM   4227  C CB  . ASP C 1 167 ? -43.139  -4.599  14.680  1.00 53.53  ? 374 ASP C CB  1 
ATOM   4228  C CG  . ASP C 1 167 ? -43.680  -5.013  16.059  1.00 75.25  ? 374 ASP C CG  1 
ATOM   4229  O OD1 . ASP C 1 167 ? -44.861  -4.703  16.392  1.00 77.07  ? 374 ASP C OD1 1 
ATOM   4230  O OD2 . ASP C 1 167 ? -42.909  -5.645  16.823  1.00 89.48  ? 374 ASP C OD2 1 
ATOM   4231  N N   . GLY C 1 168 ? -42.166  -7.121  13.398  1.00 62.48  ? 375 GLY C N   1 
ATOM   4232  C CA  . GLY C 1 168 ? -41.638  -8.452  13.604  1.00 60.46  ? 375 GLY C CA  1 
ATOM   4233  C C   . GLY C 1 168 ? -42.373  -9.539  12.861  1.00 52.18  ? 375 GLY C C   1 
ATOM   4234  O O   . GLY C 1 168 ? -42.429  -9.521  11.627  1.00 59.56  ? 375 GLY C O   1 
ATOM   4235  N N   . ASP C 1 169 ? -42.949  -10.492 13.601  1.00 48.64  ? 376 ASP C N   1 
ATOM   4236  C CA  . ASP C 1 169 ? -43.653  -11.603 12.969  1.00 47.00  ? 376 ASP C CA  1 
ATOM   4237  C C   . ASP C 1 169 ? -45.063  -11.232 12.536  1.00 50.02  ? 376 ASP C C   1 
ATOM   4238  O O   . ASP C 1 169 ? -45.886  -12.123 12.260  1.00 45.16  ? 376 ASP C O   1 
ATOM   4239  C CB  . ASP C 1 169 ? -43.681  -12.818 13.897  1.00 36.82  ? 376 ASP C CB  1 
ATOM   4240  C CG  . ASP C 1 169 ? -43.901  -14.116 13.135  1.00 49.81  ? 376 ASP C CG  1 
ATOM   4241  O OD1 . ASP C 1 169 ? -43.675  -14.114 11.898  1.00 50.12  ? 376 ASP C OD1 1 
ATOM   4242  O OD2 . ASP C 1 169 ? -44.324  -15.126 13.754  1.00 43.15  ? 376 ASP C OD2 1 
ATOM   4243  N N   . ASN C 1 170 ? -45.360  -9.933  12.479  1.00 51.40  ? 377 ASN C N   1 
ATOM   4244  C CA  . ASN C 1 170 ? -46.667  -9.440  12.071  1.00 49.60  ? 377 ASN C CA  1 
ATOM   4245  C C   . ASN C 1 170 ? -46.508  -8.191  11.229  1.00 53.78  ? 377 ASN C C   1 
ATOM   4246  O O   . ASN C 1 170 ? -47.226  -7.204  11.404  1.00 51.01  ? 377 ASN C O   1 
ATOM   4247  C CB  . ASN C 1 170 ? -47.553  -9.173  13.278  1.00 48.51  ? 377 ASN C CB  1 
ATOM   4248  C CG  . ASN C 1 170 ? -47.916  -10.442 14.028  1.00 49.38  ? 377 ASN C CG  1 
ATOM   4249  O OD1 . ASN C 1 170 ? -48.803  -11.189 13.611  1.00 49.00  ? 377 ASN C OD1 1 
ATOM   4250  N ND2 . ASN C 1 170 ? -47.219  -10.700 15.133  1.00 47.50  ? 377 ASN C ND2 1 
ATOM   4251  N N   . LYS C 1 171 ? -45.536  -8.208  10.321  1.00 56.12  ? 378 LYS C N   1 
ATOM   4252  C CA  . LYS C 1 171 ? -45.458  -7.161  9.317   1.00 55.03  ? 378 LYS C CA  1 
ATOM   4253  C C   . LYS C 1 171 ? -46.628  -7.296  8.338   1.00 53.81  ? 378 LYS C C   1 
ATOM   4254  O O   . LYS C 1 171 ? -47.217  -8.370  8.164   1.00 56.70  ? 378 LYS C O   1 
ATOM   4255  C CB  . LYS C 1 171 ? -44.114  -7.213  8.579   1.00 53.92  ? 378 LYS C CB  1 
ATOM   4256  C CG  . LYS C 1 171 ? -42.888  -6.904  9.452   1.00 53.34  ? 378 LYS C CG  1 
ATOM   4257  C CD  . LYS C 1 171 ? -41.568  -6.908  8.648   1.00 54.94  ? 378 LYS C CD  1 
ATOM   4258  C CE  . LYS C 1 171 ? -40.350  -6.598  9.547   1.00 73.25  ? 378 LYS C CE  1 
ATOM   4259  N NZ  . LYS C 1 171 ? -39.163  -6.038  8.824   1.00 69.19  ? 378 LYS C NZ  1 
ATOM   4260  N N   . TYR C 1 172 ? -46.973  -6.177  7.713   1.00 54.98  ? 379 TYR C N   1 
ATOM   4261  C CA  . TYR C 1 172 ? -48.106  -6.094  6.800   1.00 53.31  ? 379 TYR C CA  1 
ATOM   4262  C C   . TYR C 1 172 ? -47.645  -6.449  5.391   1.00 53.80  ? 379 TYR C C   1 
ATOM   4263  O O   . TYR C 1 172 ? -46.608  -5.965  4.929   1.00 52.91  ? 379 TYR C O   1 
ATOM   4264  C CB  . TYR C 1 172 ? -48.700  -4.679  6.855   1.00 52.57  ? 379 TYR C CB  1 
ATOM   4265  C CG  . TYR C 1 172 ? -49.712  -4.327  5.774   1.00 53.09  ? 379 TYR C CG  1 
ATOM   4266  C CD1 . TYR C 1 172 ? -50.874  -5.051  5.630   1.00 52.20  ? 379 TYR C CD1 1 
ATOM   4267  C CD2 . TYR C 1 172 ? -49.508  -3.244  4.928   1.00 54.22  ? 379 TYR C CD2 1 
ATOM   4268  C CE1 . TYR C 1 172 ? -51.802  -4.728  4.658   1.00 59.06  ? 379 TYR C CE1 1 
ATOM   4269  C CE2 . TYR C 1 172 ? -50.421  -2.914  3.950   1.00 53.92  ? 379 TYR C CE2 1 
ATOM   4270  C CZ  . TYR C 1 172 ? -51.570  -3.662  3.814   1.00 60.62  ? 379 TYR C CZ  1 
ATOM   4271  O OH  . TYR C 1 172 ? -52.508  -3.339  2.849   1.00 54.45  ? 379 TYR C OH  1 
ATOM   4272  N N   . ASP C 1 173 ? -48.411  -7.295  4.699   1.00 53.06  ? 380 ASP C N   1 
ATOM   4273  C CA  . ASP C 1 173 ? -48.092  -7.633  3.288   1.00 55.04  ? 380 ASP C CA  1 
ATOM   4274  C C   . ASP C 1 173 ? -48.399  -6.399  2.463   1.00 60.74  ? 380 ASP C C   1 
ATOM   4275  O O   . ASP C 1 173 ? -49.574  -6.130  2.194   1.00 62.73  ? 380 ASP C O   1 
ATOM   4276  C CB  . ASP C 1 173 ? -48.815  -8.877  2.773   1.00 54.13  ? 380 ASP C CB  1 
ATOM   4277  C CG  . ASP C 1 173 ? -48.484  -9.216  1.331   1.00 63.71  ? 380 ASP C CG  1 
ATOM   4278  O OD1 . ASP C 1 173 ? -47.324  -9.015  0.930   1.00 65.39  ? 380 ASP C OD1 1 
ATOM   4279  O OD2 . ASP C 1 173 ? -49.390  -9.681  0.622   1.00 72.62  ? 380 ASP C OD2 1 
ATOM   4280  N N   . ALA C 1 174 ? -47.358  -5.689  2.086   1.00 54.34  ? 381 ALA C N   1 
ATOM   4281  C CA  . ALA C 1 174 ? -47.527  -4.420  1.380   1.00 55.02  ? 381 ALA C CA  1 
ATOM   4282  C C   . ALA C 1 174 ? -47.343  -4.557  -0.128  1.00 62.99  ? 381 ALA C C   1 
ATOM   4283  O O   . ALA C 1 174 ? -46.701  -3.701  -0.753  1.00 62.67  ? 381 ALA C O   1 
ATOM   4284  C CB  . ALA C 1 174 ? -46.564  -3.374  1.933   1.00 58.02  ? 381 ALA C CB  1 
ATOM   4285  N N   . GLY C 1 175 ? -47.888  -5.624  -0.730  1.00 63.65  ? 382 GLY C N   1 
ATOM   4286  C CA  . GLY C 1 175 ? -47.852  -5.783  -2.179  1.00 54.03  ? 382 GLY C CA  1 
ATOM   4287  C C   . GLY C 1 175 ? -46.436  -5.797  -2.737  1.00 60.96  ? 382 GLY C C   1 
ATOM   4288  O O   . GLY C 1 175 ? -45.560  -6.533  -2.271  1.00 59.77  ? 382 GLY C O   1 
ATOM   4289  N N   . GLU C 1 176 ? -46.200  -4.956  -3.743  1.00 65.60  ? 383 GLU C N   1 
ATOM   4290  C CA  . GLU C 1 176 ? -44.909  -4.875  -4.411  1.00 60.29  ? 383 GLU C CA  1 
ATOM   4291  C C   . GLU C 1 176 ? -43.814  -4.345  -3.506  1.00 60.98  ? 383 GLU C C   1 
ATOM   4292  O O   . GLU C 1 176 ? -42.670  -4.258  -3.952  1.00 61.88  ? 383 GLU C O   1 
ATOM   4293  C CB  . GLU C 1 176 ? -45.011  -4.006  -5.669  1.00 59.36  ? 383 GLU C CB  1 
ATOM   4294  N N   . HIS C 1 177 ? -44.110  -4.004  -2.257  1.00 60.56  ? 384 HIS C N   1 
ATOM   4295  C CA  . HIS C 1 177 ? -43.072  -3.650  -1.298  1.00 61.64  ? 384 HIS C CA  1 
ATOM   4296  C C   . HIS C 1 177 ? -42.707  -4.799  -0.364  1.00 62.51  ? 384 HIS C C   1 
ATOM   4297  O O   . HIS C 1 177 ? -41.829  -4.629  0.496   1.00 60.24  ? 384 HIS C O   1 
ATOM   4298  C CB  . HIS C 1 177 ? -43.508  -2.438  -0.474  1.00 59.48  ? 384 HIS C CB  1 
ATOM   4299  C CG  . HIS C 1 177 ? -43.623  -1.174  -1.273  1.00 67.17  ? 384 HIS C CG  1 
ATOM   4300  N ND1 . HIS C 1 177 ? -42.531  -0.526  -1.808  1.00 65.41  ? 384 HIS C ND1 1 
ATOM   4301  C CD2 . HIS C 1 177 ? -44.702  -0.433  -1.618  1.00 67.38  ? 384 HIS C CD2 1 
ATOM   4302  C CE1 . HIS C 1 177 ? -42.931  0.559   -2.445  1.00 58.79  ? 384 HIS C CE1 1 
ATOM   4303  N NE2 . HIS C 1 177 ? -44.244  0.642   -2.339  1.00 66.90  ? 384 HIS C NE2 1 
ATOM   4304  N N   . GLY C 1 178 ? -43.354  -5.959  -0.511  1.00 52.20  ? 385 GLY C N   1 
ATOM   4305  C CA  . GLY C 1 178 ? -43.157  -7.049  0.424   1.00 49.97  ? 385 GLY C CA  1 
ATOM   4306  C C   . GLY C 1 178 ? -43.723  -6.759  1.810   1.00 55.32  ? 385 GLY C C   1 
ATOM   4307  O O   . GLY C 1 178 ? -44.610  -5.921  2.004   1.00 62.18  ? 385 GLY C O   1 
ATOM   4308  N N   . LEU C 1 179 ? -43.175  -7.491  2.779   1.00 48.15  ? 386 LEU C N   1 
ATOM   4309  C CA  . LEU C 1 179 ? -43.604  -7.314  4.184   1.00 48.34  ? 386 LEU C CA  1 
ATOM   4310  C C   . LEU C 1 179 ? -42.996  -6.024  4.702   1.00 47.63  ? 386 LEU C C   1 
ATOM   4311  O O   . LEU C 1 179 ? -41.815  -5.790  4.435   1.00 56.19  ? 386 LEU C O   1 
ATOM   4312  C CB  . LEU C 1 179 ? -43.192  -8.538  4.999   1.00 46.51  ? 386 LEU C CB  1 
ATOM   4313  C CG  . LEU C 1 179 ? -43.962  -9.813  4.665   1.00 56.44  ? 386 LEU C CG  1 
ATOM   4314  C CD1 . LEU C 1 179 ? -43.306  -11.027 5.298   1.00 48.08  ? 386 LEU C CD1 1 
ATOM   4315  C CD2 . LEU C 1 179 ? -45.409  -9.701  5.109   1.00 55.28  ? 386 LEU C CD2 1 
ATOM   4316  N N   . GLN C 1 180 ? -43.756  -5.265  5.476   1.00 49.64  ? 387 GLN C N   1 
ATOM   4317  C CA  . GLN C 1 180 ? -43.372  -3.922  5.872   1.00 50.87  ? 387 GLN C CA  1 
ATOM   4318  C C   . GLN C 1 180 ? -43.869  -3.617  7.268   1.00 55.11  ? 387 GLN C C   1 
ATOM   4319  O O   . GLN C 1 180 ? -44.990  -3.984  7.628   1.00 58.31  ? 387 GLN C O   1 
ATOM   4320  C CB  . GLN C 1 180 ? -43.942  -2.891  4.920   1.00 54.94  ? 387 GLN C CB  1 
ATOM   4321  C CG  . GLN C 1 180 ? -43.329  -2.933  3.565   1.00 57.40  ? 387 GLN C CG  1 
ATOM   4322  C CD  . GLN C 1 180 ? -41.972  -2.324  3.576   1.00 53.12  ? 387 GLN C CD  1 
ATOM   4323  O OE1 . GLN C 1 180 ? -41.675  -1.481  4.422   1.00 54.24  ? 387 GLN C OE1 1 
ATOM   4324  N NE2 . GLN C 1 180 ? -41.128  -2.742  2.642   1.00 53.17  ? 387 GLN C NE2 1 
ATOM   4325  N N   . GLU C 1 181 ? -43.031  -2.943  8.047   1.00 55.32  ? 388 GLU C N   1 
ATOM   4326  C CA  . GLU C 1 181 ? -43.496  -2.418  9.313   1.00 57.77  ? 388 GLU C CA  1 
ATOM   4327  C C   . GLU C 1 181 ? -44.635  -1.456  9.045   1.00 58.46  ? 388 GLU C C   1 
ATOM   4328  O O   . GLU C 1 181 ? -44.507  -0.549  8.217   1.00 61.48  ? 388 GLU C O   1 
ATOM   4329  C CB  . GLU C 1 181 ? -42.361  -1.715  10.043  1.00 62.29  ? 388 GLU C CB  1 
ATOM   4330  C CG  . GLU C 1 181 ? -41.124  -2.560  10.191  1.00 68.31  ? 388 GLU C CG  1 
ATOM   4331  C CD  . GLU C 1 181 ? -40.117  -1.944  11.136  1.00 83.36  ? 388 GLU C CD  1 
ATOM   4332  O OE1 . GLU C 1 181 ? -40.425  -0.874  11.713  1.00 77.42  ? 388 GLU C OE1 1 
ATOM   4333  O OE2 . GLU C 1 181 ? -39.024  -2.537  11.303  1.00 89.95  ? 388 GLU C OE2 1 
ATOM   4334  N N   . ALA C 1 182 ? -45.756  -1.662  9.726   1.00 56.01  ? 389 ALA C N   1 
ATOM   4335  C CA  . ALA C 1 182 ? -46.920  -0.827  9.494   1.00 56.73  ? 389 ALA C CA  1 
ATOM   4336  C C   . ALA C 1 182 ? -47.545  -0.389  10.811  1.00 60.75  ? 389 ALA C C   1 
ATOM   4337  O O   . ALA C 1 182 ? -47.177  -0.856  11.892  1.00 61.38  ? 389 ALA C O   1 
ATOM   4338  C CB  . ALA C 1 182 ? -47.958  -1.548  8.646   1.00 54.52  ? 389 ALA C CB  1 
ATOM   4339  N N   . GLU C 1 183 ? -48.489  0.546   10.685  1.00 59.99  ? 390 GLU C N   1 
ATOM   4340  C CA  . GLU C 1 183 ? -49.385  0.995   11.740  1.00 52.65  ? 390 GLU C CA  1 
ATOM   4341  C C   . GLU C 1 183 ? -50.813  0.638   11.343  1.00 50.96  ? 390 GLU C C   1 
ATOM   4342  O O   . GLU C 1 183 ? -51.196  0.812   10.180  1.00 46.81  ? 390 GLU C O   1 
ATOM   4343  C CB  . GLU C 1 183 ? -49.296  2.503   11.938  1.00 52.25  ? 390 GLU C CB  1 
ATOM   4344  C CG  . GLU C 1 183 ? -48.308  3.006   12.947  1.00 58.97  ? 390 GLU C CG  1 
ATOM   4345  C CD  . GLU C 1 183 ? -48.463  4.517   13.142  1.00 67.18  ? 390 GLU C CD  1 
ATOM   4346  O OE1 . GLU C 1 183 ? -49.257  5.112   12.371  1.00 63.74  ? 390 GLU C OE1 1 
ATOM   4347  O OE2 . GLU C 1 183 ? -47.818  5.105   14.051  1.00 64.20  ? 390 GLU C OE2 1 
ATOM   4348  N N   . LYS C 1 184 ? -51.594  0.157   12.317  1.00 45.40  ? 391 LYS C N   1 
ATOM   4349  C CA  . LYS C 1 184 ? -52.997  -0.183  12.135  1.00 42.70  ? 391 LYS C CA  1 
ATOM   4350  C C   . LYS C 1 184 ? -53.866  0.608   13.107  1.00 45.03  ? 391 LYS C C   1 
ATOM   4351  O O   . LYS C 1 184 ? -53.478  0.846   14.252  1.00 45.96  ? 391 LYS C O   1 
ATOM   4352  C CB  . LYS C 1 184 ? -53.236  -1.667  12.337  1.00 41.65  ? 391 LYS C CB  1 
ATOM   4353  C CG  . LYS C 1 184 ? -54.563  -2.146  11.778  1.00 50.04  ? 391 LYS C CG  1 
ATOM   4354  C CD  . LYS C 1 184 ? -54.808  -3.626  12.067  1.00 51.76  ? 391 LYS C CD  1 
ATOM   4355  C CE  . LYS C 1 184 ? -55.969  -4.188  11.221  1.00 56.76  ? 391 LYS C CE  1 
ATOM   4356  N NZ  . LYS C 1 184 ? -57.305  -4.143  11.905  1.00 61.23  ? 391 LYS C NZ  1 
ATOM   4357  N N   . GLY C 1 185 ? -55.046  1.014   12.651  1.00 42.90  ? 392 GLY C N   1 
ATOM   4358  C CA  . GLY C 1 185 ? -55.980  1.725   13.503  1.00 39.19  ? 392 GLY C CA  1 
ATOM   4359  C C   . GLY C 1 185 ? -57.423  1.464   13.124  1.00 47.13  ? 392 GLY C C   1 
ATOM   4360  O O   . GLY C 1 185 ? -57.760  1.418   11.933  1.00 53.40  ? 392 GLY C O   1 
ATOM   4361  N N   . VAL C 1 186 ? -58.294  1.280   14.113  1.00 44.72  ? 393 VAL C N   1 
ATOM   4362  C CA  . VAL C 1 186 ? -59.707  1.024   13.856  1.00 45.72  ? 393 VAL C CA  1 
ATOM   4363  C C   . VAL C 1 186 ? -60.526  2.161   14.447  1.00 45.85  ? 393 VAL C C   1 
ATOM   4364  O O   . VAL C 1 186 ? -60.165  2.716   15.493  1.00 49.95  ? 393 VAL C O   1 
ATOM   4365  C CB  . VAL C 1 186 ? -60.176  -0.344  14.408  1.00 41.55  ? 393 VAL C CB  1 
ATOM   4366  C CG1 . VAL C 1 186 ? -61.591  -0.647  13.949  1.00 43.30  ? 393 VAL C CG1 1 
ATOM   4367  C CG2 . VAL C 1 186 ? -59.274  -1.450  13.931  1.00 41.41  ? 393 VAL C CG2 1 
ATOM   4368  N N   . LYS C 1 187 ? -61.596  2.539   13.738  1.00 41.08  ? 394 LYS C N   1 
ATOM   4369  C CA  . LYS C 1 187 ? -62.601  3.456   14.248  1.00 45.19  ? 394 LYS C CA  1 
ATOM   4370  C C   . LYS C 1 187 ? -63.948  2.943   13.769  1.00 45.04  ? 394 LYS C C   1 
ATOM   4371  O O   . LYS C 1 187 ? -64.025  2.008   12.973  1.00 49.07  ? 394 LYS C O   1 
ATOM   4372  C CB  . LYS C 1 187 ? -62.345  4.902   13.807  1.00 42.01  ? 394 LYS C CB  1 
ATOM   4373  C CG  . LYS C 1 187 ? -61.403  5.678   14.726  1.00 41.83  ? 394 LYS C CG  1 
ATOM   4374  C CD  . LYS C 1 187 ? -62.192  6.628   15.640  1.00 56.06  ? 394 LYS C CD  1 
ATOM   4375  C CE  . LYS C 1 187 ? -61.510  8.000   15.848  1.00 56.15  ? 394 LYS C CE  1 
ATOM   4376  N NZ  . LYS C 1 187 ? -60.197  7.851   16.582  1.00 52.93  ? 394 LYS C NZ  1 
ATOM   4377  N N   . PHE C 1 188 ? -65.022  3.534   14.276  1.00 45.03  ? 395 PHE C N   1 
ATOM   4378  C CA  . PHE C 1 188 ? -66.374  3.085   13.957  1.00 47.11  ? 395 PHE C CA  1 
ATOM   4379  C C   . PHE C 1 188 ? -67.017  4.017   12.942  1.00 46.83  ? 395 PHE C C   1 
ATOM   4380  O O   . PHE C 1 188 ? -67.059  5.235   13.143  1.00 50.40  ? 395 PHE C O   1 
ATOM   4381  C CB  . PHE C 1 188 ? -67.245  3.024   15.215  1.00 43.03  ? 395 PHE C CB  1 
ATOM   4382  C CG  . PHE C 1 188 ? -66.816  1.980   16.176  1.00 45.49  ? 395 PHE C CG  1 
ATOM   4383  C CD1 . PHE C 1 188 ? -65.849  2.253   17.113  1.00 40.86  ? 395 PHE C CD1 1 
ATOM   4384  C CD2 . PHE C 1 188 ? -67.363  0.707   16.125  1.00 45.46  ? 395 PHE C CD2 1 
ATOM   4385  C CE1 . PHE C 1 188 ? -65.446  1.284   17.996  1.00 43.25  ? 395 PHE C CE1 1 
ATOM   4386  C CE2 . PHE C 1 188 ? -66.957  -0.255  16.996  1.00 41.49  ? 395 PHE C CE2 1 
ATOM   4387  C CZ  . PHE C 1 188 ? -66.002  0.026   17.932  1.00 42.68  ? 395 PHE C CZ  1 
ATOM   4388  N N   . LEU C 1 189 ? -67.535  3.457   11.866  1.00 43.45  ? 396 LEU C N   1 
ATOM   4389  C CA  . LEU C 1 189 ? -68.305  4.328   11.000  1.00 42.48  ? 396 LEU C CA  1 
ATOM   4390  C C   . LEU C 1 189 ? -69.684  4.541   11.585  1.00 43.59  ? 396 LEU C C   1 
ATOM   4391  O O   . LEU C 1 189 ? -70.158  5.676   11.669  1.00 47.59  ? 396 LEU C O   1 
ATOM   4392  C CB  . LEU C 1 189 ? -68.382  3.752   9.587   1.00 48.75  ? 396 LEU C CB  1 
ATOM   4393  C CG  . LEU C 1 189 ? -67.052  3.662   8.825   1.00 49.73  ? 396 LEU C CG  1 
ATOM   4394  C CD1 . LEU C 1 189 ? -67.275  3.317   7.349   1.00 43.12  ? 396 LEU C CD1 1 
ATOM   4395  C CD2 . LEU C 1 189 ? -66.275  4.952   8.971   1.00 44.32  ? 396 LEU C CD2 1 
ATOM   4396  N N   . THR C 1 190 ? -70.324  3.455   12.017  1.00 41.95  ? 397 THR C N   1 
ATOM   4397  C CA  . THR C 1 190 ? -71.647  3.493   12.620  1.00 38.45  ? 397 THR C CA  1 
ATOM   4398  C C   . THR C 1 190 ? -71.690  2.587   13.843  1.00 41.25  ? 397 THR C C   1 
ATOM   4399  O O   . THR C 1 190 ? -70.952  1.603   13.934  1.00 45.06  ? 397 THR C O   1 
ATOM   4400  C CB  . THR C 1 190 ? -72.745  3.069   11.631  1.00 43.03  ? 397 THR C CB  1 
ATOM   4401  O OG1 . THR C 1 190 ? -72.613  1.674   11.312  1.00 53.06  ? 397 THR C OG1 1 
ATOM   4402  C CG2 . THR C 1 190 ? -72.667  3.876   10.361  1.00 35.02  ? 397 THR C CG2 1 
ATOM   4403  N N   . LEU C 1 191 ? -72.545  2.954   14.799  1.00 40.94  ? 398 LEU C N   1 
ATOM   4404  C CA  . LEU C 1 191 ? -72.918  2.175   15.957  1.00 38.96  ? 398 LEU C CA  1 
ATOM   4405  C C   . LEU C 1 191 ? -74.413  1.904   15.927  1.00 41.17  ? 398 LEU C C   1 
ATOM   4406  O O   . LEU C 1 191 ? -75.193  2.814   15.662  1.00 45.98  ? 398 LEU C O   1 
ATOM   4407  C CB  . LEU C 1 191 ? -72.562  2.904   17.235  1.00 36.96  ? 398 LEU C CB  1 
ATOM   4408  C CG  . LEU C 1 191 ? -71.087  3.189   17.425  1.00 36.61  ? 398 LEU C CG  1 
ATOM   4409  C CD1 . LEU C 1 191 ? -70.963  4.513   18.091  1.00 33.02  ? 398 LEU C CD1 1 
ATOM   4410  C CD2 . LEU C 1 191 ? -70.436  2.112   18.280  1.00 34.54  ? 398 LEU C CD2 1 
ATOM   4411  N N   . PRO C 1 192 ? -74.845  0.672   16.159  1.00 47.11  ? 399 PRO C N   1 
ATOM   4412  C CA  . PRO C 1 192 ? -76.226  0.287   15.788  1.00 48.10  ? 399 PRO C CA  1 
ATOM   4413  C C   . PRO C 1 192 ? -77.238  0.767   16.819  1.00 45.64  ? 399 PRO C C   1 
ATOM   4414  O O   . PRO C 1 192 ? -76.860  1.247   17.900  1.00 43.85  ? 399 PRO C O   1 
ATOM   4415  C CB  . PRO C 1 192 ? -76.150  -1.247  15.722  1.00 42.65  ? 399 PRO C CB  1 
ATOM   4416  C CG  . PRO C 1 192 ? -75.067  -1.587  16.679  1.00 43.89  ? 399 PRO C CG  1 
ATOM   4417  C CD  . PRO C 1 192 ? -74.082  -0.459  16.720  1.00 39.72  ? 399 PRO C CD  1 
ATOM   4418  N N   . PRO C 1 193 ? -78.541  0.699   16.509  1.00 42.47  ? 400 PRO C N   1 
ATOM   4419  C CA  . PRO C 1 193 ? -79.542  1.060   17.531  1.00 47.99  ? 400 PRO C CA  1 
ATOM   4420  C C   . PRO C 1 193 ? -79.426  0.227   18.798  1.00 49.60  ? 400 PRO C C   1 
ATOM   4421  O O   . PRO C 1 193 ? -79.402  0.785   19.905  1.00 43.18  ? 400 PRO C O   1 
ATOM   4422  C CB  . PRO C 1 193 ? -80.876  0.833   16.805  1.00 51.36  ? 400 PRO C CB  1 
ATOM   4423  C CG  . PRO C 1 193 ? -80.546  0.923   15.362  1.00 47.41  ? 400 PRO C CG  1 
ATOM   4424  C CD  . PRO C 1 193 ? -79.172  0.361   15.225  1.00 43.64  ? 400 PRO C CD  1 
ATOM   4425  N N   . VAL C 1 194 ? -79.345  -1.102  18.665  1.00 50.57  ? 401 VAL C N   1 
ATOM   4426  C CA  . VAL C 1 194 ? -79.057  -1.992  19.789  1.00 51.93  ? 401 VAL C CA  1 
ATOM   4427  C C   . VAL C 1 194 ? -77.584  -2.369  19.740  1.00 48.49  ? 401 VAL C C   1 
ATOM   4428  O O   . VAL C 1 194 ? -77.086  -2.823  18.705  1.00 49.85  ? 401 VAL C O   1 
ATOM   4429  C CB  . VAL C 1 194 ? -79.948  -3.246  19.761  1.00 55.90  ? 401 VAL C CB  1 
ATOM   4430  C CG1 . VAL C 1 194 ? -79.535  -4.198  20.865  1.00 51.78  ? 401 VAL C CG1 1 
ATOM   4431  C CG2 . VAL C 1 194 ? -81.430  -2.860  19.888  1.00 52.61  ? 401 VAL C CG2 1 
ATOM   4432  N N   . LEU C 1 195 ? -76.877  -2.084  20.834  1.00 46.52  ? 402 LEU C N   1 
ATOM   4433  C CA  . LEU C 1 195 ? -75.415  -2.305  20.887  1.00 46.41  ? 402 LEU C CA  1 
ATOM   4434  C C   . LEU C 1 195 ? -75.093  -3.452  21.836  1.00 50.45  ? 402 LEU C C   1 
ATOM   4435  O O   . LEU C 1 195 ? -75.383  -3.336  23.026  1.00 56.75  ? 402 LEU C O   1 
ATOM   4436  C CB  . LEU C 1 195 ? -74.754  -1.006  21.353  1.00 43.90  ? 402 LEU C CB  1 
ATOM   4437  C CG  . LEU C 1 195 ? -73.236  -1.014  21.474  1.00 43.20  ? 402 LEU C CG  1 
ATOM   4438  C CD1 . LEU C 1 195 ? -72.595  -1.024  20.101  1.00 44.36  ? 402 LEU C CD1 1 
ATOM   4439  C CD2 . LEU C 1 195 ? -72.772  0.194   22.264  1.00 41.17  ? 402 LEU C CD2 1 
ATOM   4440  N N   . HIS C 1 196 ? -74.508  -4.513  21.298  1.00 49.81  ? 403 HIS C N   1 
ATOM   4441  C CA  . HIS C 1 196 ? -74.094  -5.679  22.106  1.00 43.16  ? 403 HIS C CA  1 
ATOM   4442  C C   . HIS C 1 196 ? -72.596  -5.570  22.363  1.00 46.80  ? 403 HIS C C   1 
ATOM   4443  O O   . HIS C 1 196 ? -71.839  -5.423  21.404  1.00 44.79  ? 403 HIS C O   1 
ATOM   4444  C CB  . HIS C 1 196 ? -74.439  -6.979  21.388  1.00 46.52  ? 403 HIS C CB  1 
ATOM   4445  C CG  . HIS C 1 196 ? -75.861  -7.413  21.464  1.00 52.80  ? 403 HIS C CG  1 
ATOM   4446  N ND1 . HIS C 1 196 ? -76.838  -6.671  22.084  1.00 50.64  ? 403 HIS C ND1 1 
ATOM   4447  C CD2 . HIS C 1 196 ? -76.468  -8.520  20.990  1.00 56.29  ? 403 HIS C CD2 1 
ATOM   4448  C CE1 . HIS C 1 196 ? -77.986  -7.305  21.992  1.00 58.69  ? 403 HIS C CE1 1 
ATOM   4449  N NE2 . HIS C 1 196 ? -77.786  -8.441  21.329  1.00 57.05  ? 403 HIS C NE2 1 
ATOM   4450  N N   . LEU C 1 197 ? -72.202  -5.607  23.626  1.00 48.04  ? 404 LEU C N   1 
ATOM   4451  C CA  . LEU C 1 197 ? -70.777  -5.520  24.012  1.00 45.40  ? 404 LEU C CA  1 
ATOM   4452  C C   . LEU C 1 197 ? -70.358  -6.822  24.689  1.00 47.01  ? 404 LEU C C   1 
ATOM   4453  O O   . LEU C 1 197 ? -70.902  -7.121  25.738  1.00 53.56  ? 404 LEU C O   1 
ATOM   4454  C CB  . LEU C 1 197 ? -70.604  -4.325  24.952  1.00 42.61  ? 404 LEU C CB  1 
ATOM   4455  C CG  . LEU C 1 197 ? -70.984  -2.965  24.375  1.00 47.34  ? 404 LEU C CG  1 
ATOM   4456  C CD1 . LEU C 1 197 ? -70.936  -1.903  25.452  1.00 38.81  ? 404 LEU C CD1 1 
ATOM   4457  C CD2 . LEU C 1 197 ? -70.060  -2.591  23.234  1.00 40.90  ? 404 LEU C CD2 1 
ATOM   4458  N N   . GLN C 1 198 ? -69.431  -7.560  24.080  1.00 47.54  ? 405 GLN C N   1 
ATOM   4459  C CA  . GLN C 1 198 ? -68.885  -8.792  24.696  1.00 43.85  ? 405 GLN C CA  1 
ATOM   4460  C C   . GLN C 1 198 ? -67.636  -8.418  25.483  1.00 47.88  ? 405 GLN C C   1 
ATOM   4461  O O   . GLN C 1 198 ? -66.661  -7.967  24.881  1.00 52.91  ? 405 GLN C O   1 
ATOM   4462  C CB  . GLN C 1 198 ? -68.523  -9.845  23.655  1.00 43.87  ? 405 GLN C CB  1 
ATOM   4463  C CG  . GLN C 1 198 ? -67.729  -11.007 24.229  1.00 47.42  ? 405 GLN C CG  1 
ATOM   4464  C CD  . GLN C 1 198 ? -67.630  -12.159 23.267  1.00 52.71  ? 405 GLN C CD  1 
ATOM   4465  O OE1 . GLN C 1 198 ? -67.448  -11.977 22.068  1.00 53.03  ? 405 GLN C OE1 1 
ATOM   4466  N NE2 . GLN C 1 198 ? -67.764  -13.362 23.792  1.00 50.53  ? 405 GLN C NE2 1 
ATOM   4467  N N   . LEU C 1 199 ? -67.689  -8.607  26.794  1.00 48.02  ? 406 LEU C N   1 
ATOM   4468  C CA  . LEU C 1 199 ? -66.535  -8.281  27.653  1.00 46.99  ? 406 LEU C CA  1 
ATOM   4469  C C   . LEU C 1 199 ? -65.555  -9.451  27.634  1.00 53.22  ? 406 LEU C C   1 
ATOM   4470  O O   . LEU C 1 199 ? -65.946  -10.545 28.008  1.00 48.90  ? 406 LEU C O   1 
ATOM   4471  C CB  . LEU C 1 199 ? -67.044  -7.932  29.053  1.00 48.81  ? 406 LEU C CB  1 
ATOM   4472  C CG  . LEU C 1 199 ? -68.065  -6.798  29.122  1.00 48.28  ? 406 LEU C CG  1 
ATOM   4473  C CD1 . LEU C 1 199 ? -68.352  -6.419  30.563  1.00 43.59  ? 406 LEU C CD1 1 
ATOM   4474  C CD2 . LEU C 1 199 ? -67.597  -5.584  28.341  1.00 44.89  ? 406 LEU C CD2 1 
ATOM   4475  N N   . MET C 1 200 ? -64.328  -9.205  27.206  1.00 55.89  ? 407 MET C N   1 
ATOM   4476  C CA  . MET C 1 200 ? -63.268  -10.196 27.068  1.00 54.03  ? 407 MET C CA  1 
ATOM   4477  C C   . MET C 1 200 ? -62.717  -10.608 28.422  1.00 61.65  ? 407 MET C C   1 
ATOM   4478  O O   . MET C 1 200 ? -61.577  -10.269 28.770  1.00 58.89  ? 407 MET C O   1 
ATOM   4479  C CB  . MET C 1 200 ? -62.140  -9.642  26.210  1.00 54.49  ? 407 MET C CB  1 
ATOM   4480  C CG  . MET C 1 200 ? -62.547  -9.317  24.818  1.00 50.09  ? 407 MET C CG  1 
ATOM   4481  S SD  . MET C 1 200 ? -62.887  -10.842 23.972  1.00 62.05  ? 407 MET C SD  1 
ATOM   4482  C CE  . MET C 1 200 ? -61.434  -10.888 22.927  1.00 60.89  ? 407 MET C CE  1 
ATOM   4483  N N   . ARG C 1 201 ? -63.521  -11.347 29.182  1.00 62.24  ? 408 ARG C N   1 
ATOM   4484  C CA  . ARG C 1 201 ? -63.171  -11.760 30.540  1.00 57.72  ? 408 ARG C CA  1 
ATOM   4485  C C   . ARG C 1 201 ? -62.518  -13.139 30.571  1.00 60.83  ? 408 ARG C C   1 
ATOM   4486  O O   . ARG C 1 201 ? -63.001  -14.013 31.279  1.00 59.53  ? 408 ARG C O   1 
ATOM   4487  C CB  . ARG C 1 201 ? -64.417  -11.743 31.417  1.00 57.02  ? 408 ARG C CB  1 
ATOM   4488  C CG  . ARG C 1 201 ? -64.834  -10.350 31.945  1.00 60.04  ? 408 ARG C CG  1 
ATOM   4489  C CD  . ARG C 1 201 ? -65.775  -10.458 33.163  1.00 49.94  ? 408 ARG C CD  1 
ATOM   4490  N NE  . ARG C 1 201 ? -66.293  -9.155  33.580  1.00 62.12  ? 408 ARG C NE  1 
ATOM   4491  C CZ  . ARG C 1 201 ? -65.731  -8.355  34.496  1.00 67.93  ? 408 ARG C CZ  1 
ATOM   4492  N NH1 . ARG C 1 201 ? -64.609  -8.716  35.124  1.00 58.61  ? 408 ARG C NH1 1 
ATOM   4493  N NH2 . ARG C 1 201 ? -66.296  -7.177  34.784  1.00 59.52  ? 408 ARG C NH2 1 
ATOM   4494  N N   . PHE C 1 202 ? -61.507  -13.343 29.727  1.00 58.14  ? 409 PHE C N   1 
ATOM   4495  C CA  . PHE C 1 202 ? -60.817  -14.652 29.629  1.00 57.88  ? 409 PHE C CA  1 
ATOM   4496  C C   . PHE C 1 202 ? -59.390  -14.452 29.110  1.00 60.47  ? 409 PHE C C   1 
ATOM   4497  O O   . PHE C 1 202 ? -59.177  -13.546 28.292  1.00 58.21  ? 409 PHE C O   1 
ATOM   4498  C CB  . PHE C 1 202 ? -61.578  -15.623 28.724  1.00 59.79  ? 409 PHE C CB  1 
ATOM   4499  C CG  . PHE C 1 202 ? -62.368  -15.030 27.586  1.00 63.60  ? 409 PHE C CG  1 
ATOM   4500  C CD1 . PHE C 1 202 ? -61.737  -14.433 26.509  1.00 65.13  ? 409 PHE C CD1 1 
ATOM   4501  C CD2 . PHE C 1 202 ? -63.749  -15.110 27.574  1.00 58.83  ? 409 PHE C CD2 1 
ATOM   4502  C CE1 . PHE C 1 202 ? -62.472  -13.910 25.461  1.00 66.98  ? 409 PHE C CE1 1 
ATOM   4503  C CE2 . PHE C 1 202 ? -64.481  -14.582 26.527  1.00 61.88  ? 409 PHE C CE2 1 
ATOM   4504  C CZ  . PHE C 1 202 ? -63.843  -13.982 25.472  1.00 60.23  ? 409 PHE C CZ  1 
ATOM   4505  N N   . ILE C 1 212 ? -58.991  -19.411 31.826  1.00 72.50  ? 419 ILE C N   1 
ATOM   4506  C CA  . ILE C 1 212 ? -59.134  -18.717 33.117  1.00 78.51  ? 419 ILE C CA  1 
ATOM   4507  C C   . ILE C 1 212 ? -59.972  -17.453 32.993  1.00 64.93  ? 419 ILE C C   1 
ATOM   4508  O O   . ILE C 1 212 ? -59.515  -16.465 32.431  1.00 66.60  ? 419 ILE C O   1 
ATOM   4509  C CB  . ILE C 1 212 ? -57.761  -18.343 33.721  1.00 75.37  ? 419 ILE C CB  1 
ATOM   4510  C CG1 . ILE C 1 212 ? -56.841  -19.562 33.783  1.00 80.27  ? 419 ILE C CG1 1 
ATOM   4511  C CG2 . ILE C 1 212 ? -57.928  -17.660 35.076  1.00 65.86  ? 419 ILE C CG2 1 
ATOM   4512  C CD1 . ILE C 1 212 ? -55.907  -19.690 32.555  1.00 93.14  ? 419 ILE C CD1 1 
ATOM   4513  N N   . LYS C 1 213 ? -61.184  -17.476 33.535  1.00 59.98  ? 420 LYS C N   1 
ATOM   4514  C CA  . LYS C 1 213 ? -62.015  -16.279 33.523  1.00 62.94  ? 420 LYS C CA  1 
ATOM   4515  C C   . LYS C 1 213 ? -61.351  -15.146 34.318  1.00 61.96  ? 420 LYS C C   1 
ATOM   4516  O O   . LYS C 1 213 ? -60.692  -15.374 35.333  1.00 66.14  ? 420 LYS C O   1 
ATOM   4517  C CB  . LYS C 1 213 ? -63.409  -16.604 34.070  1.00 59.04  ? 420 LYS C CB  1 
ATOM   4518  C CG  . LYS C 1 213 ? -64.203  -15.398 34.546  1.00 59.66  ? 420 LYS C CG  1 
ATOM   4519  C CD  . LYS C 1 213 ? -65.633  -15.739 34.967  1.00 62.43  ? 420 LYS C CD  1 
ATOM   4520  C CE  . LYS C 1 213 ? -66.456  -14.457 35.062  1.00 60.79  ? 420 LYS C CE  1 
ATOM   4521  N NZ  . LYS C 1 213 ? -67.756  -14.547 35.771  1.00 60.21  ? 420 LYS C NZ  1 
ATOM   4522  N N   . ILE C 1 214 ? -61.495  -13.920 33.822  1.00 57.74  ? 421 ILE C N   1 
ATOM   4523  C CA  . ILE C 1 214 ? -60.966  -12.726 34.466  1.00 59.20  ? 421 ILE C CA  1 
ATOM   4524  C C   . ILE C 1 214 ? -62.085  -12.080 35.258  1.00 62.81  ? 421 ILE C C   1 
ATOM   4525  O O   . ILE C 1 214 ? -63.196  -11.914 34.737  1.00 65.41  ? 421 ILE C O   1 
ATOM   4526  C CB  . ILE C 1 214 ? -60.413  -11.745 33.425  1.00 62.83  ? 421 ILE C CB  1 
ATOM   4527  C CG1 . ILE C 1 214 ? -59.347  -12.460 32.571  1.00 59.55  ? 421 ILE C CG1 1 
ATOM   4528  C CG2 . ILE C 1 214 ? -59.977  -10.435 34.097  1.00 53.54  ? 421 ILE C CG2 1 
ATOM   4529  C CD1 . ILE C 1 214 ? -58.900  -11.687 31.364  1.00 56.76  ? 421 ILE C CD1 1 
ATOM   4530  N N   . ASN C 1 215 ? -61.834  -11.786 36.534  1.00 61.77  ? 422 ASN C N   1 
ATOM   4531  C CA  . ASN C 1 215 ? -62.910  -11.257 37.409  1.00 57.71  ? 422 ASN C CA  1 
ATOM   4532  C C   . ASN C 1 215 ? -62.503  -9.884  37.939  1.00 59.81  ? 422 ASN C C   1 
ATOM   4533  O O   . ASN C 1 215 ? -62.995  -9.506  39.008  1.00 58.62  ? 422 ASN C O   1 
ATOM   4534  C CB  . ASN C 1 215 ? -63.227  -12.246 38.530  1.00 55.19  ? 422 ASN C CB  1 
ATOM   4535  C CG  . ASN C 1 215 ? -63.707  -13.592 38.040  1.00 60.92  ? 422 ASN C CG  1 
ATOM   4536  O OD1 . ASN C 1 215 ? -64.884  -13.757 37.752  1.00 60.56  ? 422 ASN C OD1 1 
ATOM   4537  N ND2 . ASN C 1 215 ? -62.811  -14.561 37.963  1.00 59.21  ? 422 ASN C ND2 1 
ATOM   4538  N N   . ASP C 1 216 ? -61.675  -9.158  37.191  1.00 58.33  ? 423 ASP C N   1 
ATOM   4539  C CA  . ASP C 1 216 ? -61.180  -7.823  37.615  1.00 58.02  ? 423 ASP C CA  1 
ATOM   4540  C C   . ASP C 1 216 ? -62.306  -6.785  37.624  1.00 58.55  ? 423 ASP C C   1 
ATOM   4541  O O   . ASP C 1 216 ? -63.349  -7.020  37.001  1.00 56.38  ? 423 ASP C O   1 
ATOM   4542  C CB  . ASP C 1 216 ? -60.040  -7.373  36.704  1.00 62.36  ? 423 ASP C CB  1 
ATOM   4543  C CG  . ASP C 1 216 ? -58.713  -8.055  36.972  1.00 70.39  ? 423 ASP C CG  1 
ATOM   4544  O OD1 . ASP C 1 216 ? -58.722  -9.249  37.323  1.00 71.88  ? 423 ASP C OD1 1 
ATOM   4545  O OD2 . ASP C 1 216 ? -57.678  -7.387  36.811  1.00 62.38  ? 423 ASP C OD2 1 
ATOM   4546  N N   . ARG C 1 217 ? -62.081  -5.658  38.297  1.00 57.30  ? 424 ARG C N   1 
ATOM   4547  C CA  . ARG C 1 217 ? -63.104  -4.590  38.372  1.00 54.65  ? 424 ARG C CA  1 
ATOM   4548  C C   . ARG C 1 217 ? -63.206  -3.904  37.018  1.00 65.08  ? 424 ARG C C   1 
ATOM   4549  O O   . ARG C 1 217 ? -62.177  -3.422  36.522  1.00 62.59  ? 424 ARG C O   1 
ATOM   4550  C CB  . ARG C 1 217 ? -62.760  -3.562  39.447  1.00 39.35  ? 424 ARG C CB  1 
ATOM   4551  N N   . PHE C 1 218 ? -64.414  -3.859  36.464  1.00 63.11  ? 425 PHE C N   1 
ATOM   4552  C CA  . PHE C 1 218 ? -64.639  -3.230  35.165  1.00 58.27  ? 425 PHE C CA  1 
ATOM   4553  C C   . PHE C 1 218 ? -65.915  -2.385  35.194  1.00 57.85  ? 425 PHE C C   1 
ATOM   4554  O O   . PHE C 1 218 ? -67.030  -2.923  35.136  1.00 56.67  ? 425 PHE C O   1 
ATOM   4555  C CB  . PHE C 1 218 ? -64.707  -4.280  34.061  1.00 61.27  ? 425 PHE C CB  1 
ATOM   4556  C CG  . PHE C 1 218 ? -64.801  -3.680  32.688  1.00 63.57  ? 425 PHE C CG  1 
ATOM   4557  C CD1 . PHE C 1 218 ? -63.664  -3.233  32.041  1.00 58.82  ? 425 PHE C CD1 1 
ATOM   4558  C CD2 . PHE C 1 218 ? -66.033  -3.512  32.069  1.00 60.54  ? 425 PHE C CD2 1 
ATOM   4559  C CE1 . PHE C 1 218 ? -63.749  -2.662  30.803  1.00 61.26  ? 425 PHE C CE1 1 
ATOM   4560  C CE2 . PHE C 1 218 ? -66.125  -2.933  30.828  1.00 56.58  ? 425 PHE C CE2 1 
ATOM   4561  C CZ  . PHE C 1 218 ? -64.983  -2.512  30.192  1.00 59.95  ? 425 PHE C CZ  1 
ATOM   4562  N N   . GLU C 1 219 ? -65.751  -1.063  35.231  1.00 54.07  ? 426 GLU C N   1 
ATOM   4563  C CA  . GLU C 1 219 ? -66.858  -0.148  35.478  1.00 56.72  ? 426 GLU C CA  1 
ATOM   4564  C C   . GLU C 1 219 ? -67.568  0.200   34.178  1.00 57.16  ? 426 GLU C C   1 
ATOM   4565  O O   . GLU C 1 219 ? -66.936  0.327   33.131  1.00 61.28  ? 426 GLU C O   1 
ATOM   4566  C CB  . GLU C 1 219 ? -66.350  1.129   36.155  1.00 56.96  ? 426 GLU C CB  1 
ATOM   4567  C CG  . GLU C 1 219 ? -65.354  0.883   37.302  1.00 62.52  ? 426 GLU C CG  1 
ATOM   4568  C CD  . GLU C 1 219 ? -64.802  2.172   37.940  1.00 68.21  ? 426 GLU C CD  1 
ATOM   4569  O OE1 . GLU C 1 219 ? -64.470  3.122   37.200  1.00 62.58  ? 426 GLU C OE1 1 
ATOM   4570  O OE2 . GLU C 1 219 ? -64.693  2.233   39.191  1.00 70.85  ? 426 GLU C OE2 1 
ATOM   4571  N N   . PHE C 1 220 ? -68.886  0.363   34.249  1.00 52.44  ? 427 PHE C N   1 
ATOM   4572  C CA  . PHE C 1 220 ? -69.624  0.732   33.046  1.00 57.02  ? 427 PHE C CA  1 
ATOM   4573  C C   . PHE C 1 220 ? -70.866  1.554   33.384  1.00 63.66  ? 427 PHE C C   1 
ATOM   4574  O O   . PHE C 1 220 ? -71.619  1.182   34.300  1.00 63.94  ? 427 PHE C O   1 
ATOM   4575  C CB  . PHE C 1 220 ? -70.021  -0.496  32.231  1.00 56.37  ? 427 PHE C CB  1 
ATOM   4576  C CG  . PHE C 1 220 ? -70.655  -1.592  33.036  1.00 56.69  ? 427 PHE C CG  1 
ATOM   4577  C CD1 . PHE C 1 220 ? -72.015  -1.592  33.275  1.00 56.63  ? 427 PHE C CD1 1 
ATOM   4578  C CD2 . PHE C 1 220 ? -69.895  -2.634  33.528  1.00 57.43  ? 427 PHE C CD2 1 
ATOM   4579  C CE1 . PHE C 1 220 ? -72.599  -2.593  34.007  1.00 56.56  ? 427 PHE C CE1 1 
ATOM   4580  C CE2 . PHE C 1 220 ? -70.478  -3.645  34.256  1.00 59.80  ? 427 PHE C CE2 1 
ATOM   4581  C CZ  . PHE C 1 220 ? -71.828  -3.623  34.500  1.00 57.27  ? 427 PHE C CZ  1 
ATOM   4582  N N   . PRO C 1 221 ? -71.111  2.645   32.670  1.00 61.49  ? 428 PRO C N   1 
ATOM   4583  C CA  . PRO C 1 221 ? -72.091  3.634   33.121  1.00 61.67  ? 428 PRO C CA  1 
ATOM   4584  C C   . PRO C 1 221 ? -73.518  3.199   32.823  1.00 65.99  ? 428 PRO C C   1 
ATOM   4585  O O   . PRO C 1 221 ? -73.774  2.271   32.057  1.00 68.85  ? 428 PRO C O   1 
ATOM   4586  C CB  . PRO C 1 221 ? -71.724  4.871   32.300  1.00 60.58  ? 428 PRO C CB  1 
ATOM   4587  C CG  . PRO C 1 221 ? -71.260  4.282   31.012  1.00 58.41  ? 428 PRO C CG  1 
ATOM   4588  C CD  . PRO C 1 221 ? -70.513  3.018   31.379  1.00 60.13  ? 428 PRO C CD  1 
ATOM   4589  N N   . GLU C 1 222 ? -74.462  3.924   33.425  1.00 70.91  ? 429 GLU C N   1 
ATOM   4590  C CA  . GLU C 1 222 ? -75.849  3.767   33.007  1.00 66.86  ? 429 GLU C CA  1 
ATOM   4591  C C   . GLU C 1 222 ? -76.082  4.449   31.670  1.00 60.95  ? 429 GLU C C   1 
ATOM   4592  O O   . GLU C 1 222 ? -76.925  4.010   30.883  1.00 63.91  ? 429 GLU C O   1 
ATOM   4593  C CB  . GLU C 1 222 ? -76.793  4.320   34.077  1.00 69.16  ? 429 GLU C CB  1 
ATOM   4594  C CG  . GLU C 1 222 ? -78.268  4.189   33.746  1.00 73.97  ? 429 GLU C CG  1 
ATOM   4595  C CD  . GLU C 1 222 ? -79.046  5.453   34.087  1.00 85.92  ? 429 GLU C CD  1 
ATOM   4596  O OE1 . GLU C 1 222 ? -78.865  5.958   35.222  1.00 85.00  ? 429 GLU C OE1 1 
ATOM   4597  O OE2 . GLU C 1 222 ? -79.820  5.945   33.219  1.00 85.39  ? 429 GLU C OE2 1 
ATOM   4598  N N   . GLN C 1 223 ? -75.289  5.477   31.382  1.00 61.00  ? 430 GLN C N   1 
ATOM   4599  C CA  . GLN C 1 223 ? -75.396  6.184   30.082  1.00 60.28  ? 430 GLN C CA  1 
ATOM   4600  C C   . GLN C 1 223 ? -74.013  6.242   29.427  1.00 56.71  ? 430 GLN C C   1 
ATOM   4601  O O   . GLN C 1 223 ? -73.118  6.825   30.042  1.00 50.92  ? 430 GLN C O   1 
ATOM   4602  C CB  . GLN C 1 223 ? -76.036  7.553   30.301  1.00 63.88  ? 430 GLN C CB  1 
ATOM   4603  C CG  . GLN C 1 223 ? -77.550  7.492   30.399  1.00 74.17  ? 430 GLN C CG  1 
ATOM   4604  C CD  . GLN C 1 223 ? -78.154  8.800   30.838  1.00 86.70  ? 430 GLN C CD  1 
ATOM   4605  O OE1 . GLN C 1 223 ? -77.846  9.860   30.299  1.00 97.24  ? 430 GLN C OE1 1 
ATOM   4606  N NE2 . GLN C 1 223 ? -79.031  8.732   31.825  1.00 87.29  ? 430 GLN C NE2 1 
ATOM   4607  N N   . LEU C 1 224 ? -73.874  5.717   28.205  1.00 56.48  ? 431 LEU C N   1 
ATOM   4608  C CA  . LEU C 1 224 ? -72.555  5.618   27.520  1.00 54.45  ? 431 LEU C CA  1 
ATOM   4609  C C   . LEU C 1 224 ? -72.407  6.627   26.384  1.00 51.62  ? 431 LEU C C   1 
ATOM   4610  O O   . LEU C 1 224 ? -73.072  6.454   25.360  1.00 57.60  ? 431 LEU C O   1 
ATOM   4611  C CB  . LEU C 1 224 ? -72.442  4.198   26.961  1.00 50.38  ? 431 LEU C CB  1 
ATOM   4612  C CG  . LEU C 1 224 ? -71.082  3.754   26.436  1.00 48.99  ? 431 LEU C CG  1 
ATOM   4613  C CD1 . LEU C 1 224 ? -69.983  4.046   27.436  1.00 52.18  ? 431 LEU C CD1 1 
ATOM   4614  C CD2 . LEU C 1 224 ? -71.106  2.276   26.094  1.00 46.06  ? 431 LEU C CD2 1 
ATOM   4615  N N   . PRO C 1 225 ? -71.596  7.692   26.534  1.00 50.03  ? 432 PRO C N   1 
ATOM   4616  C CA  . PRO C 1 225 ? -71.294  8.586   25.413  1.00 55.02  ? 432 PRO C CA  1 
ATOM   4617  C C   . PRO C 1 225 ? -70.222  7.982   24.489  1.00 48.73  ? 432 PRO C C   1 
ATOM   4618  O O   . PRO C 1 225 ? -69.146  7.705   24.954  1.00 45.57  ? 432 PRO C O   1 
ATOM   4619  C CB  . PRO C 1 225 ? -70.821  9.865   26.112  1.00 54.18  ? 432 PRO C CB  1 
ATOM   4620  C CG  . PRO C 1 225 ? -70.333  9.442   27.474  1.00 47.08  ? 432 PRO C CG  1 
ATOM   4621  C CD  . PRO C 1 225 ? -71.083  8.175   27.807  1.00 48.35  ? 432 PRO C CD  1 
ATOM   4622  N N   . LEU C 1 226 ? -70.524  7.814   23.198  1.00 47.24  ? 433 LEU C N   1 
ATOM   4623  C CA  . LEU C 1 226 ? -69.577  7.102   22.291  1.00 50.84  ? 433 LEU C CA  1 
ATOM   4624  C C   . LEU C 1 226 ? -69.189  7.909   21.045  1.00 54.46  ? 433 LEU C C   1 
ATOM   4625  O O   . LEU C 1 226 ? -68.615  7.300   20.132  1.00 50.73  ? 433 LEU C O   1 
ATOM   4626  C CB  . LEU C 1 226 ? -70.231  5.789   21.859  1.00 48.35  ? 433 LEU C CB  1 
ATOM   4627  C CG  . LEU C 1 226 ? -70.211  4.653   22.875  1.00 49.87  ? 433 LEU C CG  1 
ATOM   4628  C CD1 . LEU C 1 226 ? -70.738  3.381   22.247  1.00 38.45  ? 433 LEU C CD1 1 
ATOM   4629  C CD2 . LEU C 1 226 ? -68.810  4.432   23.409  1.00 52.39  ? 433 LEU C CD2 1 
ATOM   4630  N N   . ASP C 1 227 ? -69.468  9.212   21.005  1.00 52.16  ? 434 ASP C N   1 
ATOM   4631  C CA  . ASP C 1 227 ? -69.174  10.010  19.810  1.00 48.71  ? 434 ASP C CA  1 
ATOM   4632  C C   . ASP C 1 227 ? -67.680  10.198  19.595  1.00 53.10  ? 434 ASP C C   1 
ATOM   4633  O O   . ASP C 1 227 ? -67.245  10.419  18.462  1.00 57.59  ? 434 ASP C O   1 
ATOM   4634  C CB  . ASP C 1 227 ? -69.836  11.385  19.906  1.00 56.07  ? 434 ASP C CB  1 
ATOM   4635  C CG  . ASP C 1 227 ? -71.190  11.434  19.243  1.00 58.55  ? 434 ASP C CG  1 
ATOM   4636  O OD1 . ASP C 1 227 ? -71.510  10.555  18.416  1.00 61.06  ? 434 ASP C OD1 1 
ATOM   4637  O OD2 . ASP C 1 227 ? -71.937  12.374  19.536  1.00 66.01  ? 434 ASP C OD2 1 
ATOM   4638  N N   . GLU C 1 228 ? -66.887  10.138  20.666  1.00 53.41  ? 435 GLU C N   1 
ATOM   4639  C CA  . GLU C 1 228 ? -65.435  10.195  20.583  1.00 51.94  ? 435 GLU C CA  1 
ATOM   4640  C C   . GLU C 1 228 ? -64.845  9.009   19.808  1.00 50.93  ? 435 GLU C C   1 
ATOM   4641  O O   . GLU C 1 228 ? -63.634  8.984   19.557  1.00 52.27  ? 435 GLU C O   1 
ATOM   4642  C CB  . GLU C 1 228 ? -64.878  10.256  22.018  1.00 55.60  ? 435 GLU C CB  1 
ATOM   4643  C CG  . GLU C 1 228 ? -63.521  10.934  22.234  1.00 65.76  ? 435 GLU C CG  1 
ATOM   4644  C CD  . GLU C 1 228 ? -62.731  10.329  23.433  1.00 83.28  ? 435 GLU C CD  1 
ATOM   4645  O OE1 . GLU C 1 228 ? -61.657  9.717   23.196  1.00 88.34  ? 435 GLU C OE1 1 
ATOM   4646  O OE2 . GLU C 1 228 ? -63.170  10.470  24.609  1.00 79.35  ? 435 GLU C OE2 1 
ATOM   4647  N N   . PHE C 1 229 ? -65.650  8.022   19.421  1.00 45.08  ? 436 PHE C N   1 
ATOM   4648  C CA  . PHE C 1 229 ? -65.105  6.845   18.762  1.00 46.04  ? 436 PHE C CA  1 
ATOM   4649  C C   . PHE C 1 229 ? -65.679  6.643   17.371  1.00 51.56  ? 436 PHE C C   1 
ATOM   4650  O O   . PHE C 1 229 ? -65.334  5.661   16.699  1.00 49.59  ? 436 PHE C O   1 
ATOM   4651  C CB  . PHE C 1 229 ? -65.314  5.610   19.646  1.00 38.24  ? 436 PHE C CB  1 
ATOM   4652  C CG  . PHE C 1 229 ? -64.908  5.846   21.085  1.00 44.27  ? 436 PHE C CG  1 
ATOM   4653  C CD1 . PHE C 1 229 ? -63.572  5.997   21.423  1.00 46.69  ? 436 PHE C CD1 1 
ATOM   4654  C CD2 . PHE C 1 229 ? -65.858  5.987   22.080  1.00 44.80  ? 436 PHE C CD2 1 
ATOM   4655  C CE1 . PHE C 1 229 ? -63.185  6.247   22.725  1.00 45.43  ? 436 PHE C CE1 1 
ATOM   4656  C CE2 . PHE C 1 229 ? -65.480  6.231   23.379  1.00 48.07  ? 436 PHE C CE2 1 
ATOM   4657  C CZ  . PHE C 1 229 ? -64.134  6.358   23.700  1.00 49.22  ? 436 PHE C CZ  1 
ATOM   4658  N N   . LEU C 1 230 ? -66.506  7.564   16.896  1.00 49.76  ? 437 LEU C N   1 
ATOM   4659  C CA  . LEU C 1 230 ? -66.911  7.524   15.508  1.00 48.80  ? 437 LEU C CA  1 
ATOM   4660  C C   . LEU C 1 230 ? -65.881  8.265   14.643  1.00 55.00  ? 437 LEU C C   1 
ATOM   4661  O O   . LEU C 1 230 ? -65.135  9.134   15.109  1.00 51.14  ? 437 LEU C O   1 
ATOM   4662  C CB  . LEU C 1 230 ? -68.300  8.132   15.346  1.00 48.66  ? 437 LEU C CB  1 
ATOM   4663  C CG  . LEU C 1 230 ? -69.487  7.405   15.979  1.00 45.28  ? 437 LEU C CG  1 
ATOM   4664  C CD1 . LEU C 1 230 ? -70.670  8.377   16.060  1.00 45.94  ? 437 LEU C CD1 1 
ATOM   4665  C CD2 . LEU C 1 230 ? -69.858  6.161   15.201  1.00 40.17  ? 437 LEU C CD2 1 
ATOM   4666  N N   . GLN C 1 231 ? -65.804  7.856   13.376  1.00 49.80  ? 438 GLN C N   1 
ATOM   4667  C CA  . GLN C 1 231 ? -65.026  8.624   12.421  1.00 48.68  ? 438 GLN C CA  1 
ATOM   4668  C C   . GLN C 1 231 ? -65.701  9.970   12.161  1.00 50.85  ? 438 GLN C C   1 
ATOM   4669  O O   . GLN C 1 231 ? -65.027  11.002  12.102  1.00 53.85  ? 438 GLN C O   1 
ATOM   4670  C CB  . GLN C 1 231 ? -64.834  7.797   11.139  1.00 44.67  ? 438 GLN C CB  1 
ATOM   4671  C CG  . GLN C 1 231 ? -63.584  8.132   10.309  1.00 51.38  ? 438 GLN C CG  1 
ATOM   4672  C CD  . GLN C 1 231 ? -62.337  8.420   11.155  1.00 55.16  ? 438 GLN C CD  1 
ATOM   4673  O OE1 . GLN C 1 231 ? -61.848  7.558   11.887  1.00 56.35  ? 438 GLN C OE1 1 
ATOM   4674  N NE2 . GLN C 1 231 ? -61.829  9.644   11.059  1.00 52.92  ? 438 GLN C NE2 1 
ATOM   4675  N N   . LYS C 1 232 ? -67.037  9.985   12.081  1.00 46.44  ? 439 LYS C N   1 
ATOM   4676  C CA  . LYS C 1 232 ? -67.827  11.200  11.912  1.00 48.01  ? 439 LYS C CA  1 
ATOM   4677  C C   . LYS C 1 232 ? -69.035  11.196  12.851  1.00 58.09  ? 439 LYS C C   1 
ATOM   4678  O O   . LYS C 1 232 ? -69.749  10.188  12.973  1.00 52.55  ? 439 LYS C O   1 
ATOM   4679  C CB  . LYS C 1 232 ? -68.320  11.354  10.472  1.00 51.76  ? 439 LYS C CB  1 
ATOM   4680  C CG  . LYS C 1 232 ? -69.008  12.666  10.195  1.00 53.10  ? 439 LYS C CG  1 
ATOM   4681  C CD  . LYS C 1 232 ? -69.072  12.905  8.709   1.00 58.39  ? 439 LYS C CD  1 
ATOM   4682  C CE  . LYS C 1 232 ? -70.187  13.866  8.354   1.00 60.66  ? 439 LYS C CE  1 
ATOM   4683  N NZ  . LYS C 1 232 ? -70.030  15.099  9.143   1.00 66.09  ? 439 LYS C NZ  1 
ATOM   4684  N N   . THR C 1 233 ? -69.276  12.331  13.504  1.00 53.54  ? 440 THR C N   1 
ATOM   4685  C CA  . THR C 1 233 ? -70.410  12.448  14.402  1.00 49.56  ? 440 THR C CA  1 
ATOM   4686  C C   . THR C 1 233 ? -71.555  13.161  13.700  1.00 54.21  ? 440 THR C C   1 
ATOM   4687  O O   . THR C 1 233 ? -71.347  13.941  12.771  1.00 61.68  ? 440 THR C O   1 
ATOM   4688  C CB  . THR C 1 233 ? -70.027  13.185  15.680  1.00 46.90  ? 440 THR C CB  1 
ATOM   4689  O OG1 . THR C 1 233 ? -69.681  14.527  15.367  1.00 50.86  ? 440 THR C OG1 1 
ATOM   4690  C CG2 . THR C 1 233 ? -68.842  12.535  16.316  1.00 47.84  ? 440 THR C CG2 1 
ATOM   4691  N N   . ASP C 1 234 ? -72.778  12.862  14.139  1.00 62.32  ? 441 ASP C N   1 
ATOM   4692  C CA  . ASP C 1 234 ? -73.991  13.459  13.584  1.00 58.20  ? 441 ASP C CA  1 
ATOM   4693  C C   . ASP C 1 234 ? -74.577  14.413  14.611  1.00 60.71  ? 441 ASP C C   1 
ATOM   4694  O O   . ASP C 1 234 ? -75.234  13.966  15.563  1.00 64.85  ? 441 ASP C O   1 
ATOM   4695  C CB  . ASP C 1 234 ? -75.002  12.368  13.225  1.00 59.06  ? 441 ASP C CB  1 
ATOM   4696  C CG  . ASP C 1 234 ? -76.242  12.904  12.532  1.00 61.92  ? 441 ASP C CG  1 
ATOM   4697  O OD1 . ASP C 1 234 ? -76.537  14.119  12.633  1.00 59.13  ? 441 ASP C OD1 1 
ATOM   4698  O OD2 . ASP C 1 234 ? -76.930  12.084  11.881  1.00 65.45  ? 441 ASP C OD2 1 
ATOM   4699  N N   . PRO C 1 235 ? -74.376  15.725  14.470  1.00 63.40  ? 442 PRO C N   1 
ATOM   4700  C CA  . PRO C 1 235 ? -74.972  16.674  15.428  1.00 63.71  ? 442 PRO C CA  1 
ATOM   4701  C C   . PRO C 1 235 ? -76.473  16.503  15.599  1.00 67.73  ? 442 PRO C C   1 
ATOM   4702  O O   . PRO C 1 235 ? -77.018  16.910  16.633  1.00 64.85  ? 442 PRO C O   1 
ATOM   4703  C CB  . PRO C 1 235 ? -74.638  18.038  14.819  1.00 64.42  ? 442 PRO C CB  1 
ATOM   4704  C CG  . PRO C 1 235 ? -73.492  17.787  13.906  1.00 60.21  ? 442 PRO C CG  1 
ATOM   4705  C CD  . PRO C 1 235 ? -73.681  16.408  13.369  1.00 63.59  ? 442 PRO C CD  1 
ATOM   4706  N N   . LYS C 1 236 ? -77.156  15.897  14.626  1.00 67.58  ? 443 LYS C N   1 
ATOM   4707  C CA  . LYS C 1 236 ? -78.563  15.581  14.805  1.00 64.53  ? 443 LYS C CA  1 
ATOM   4708  C C   . LYS C 1 236 ? -78.759  14.354  15.691  1.00 67.36  ? 443 LYS C C   1 
ATOM   4709  O O   . LYS C 1 236 ? -79.770  14.262  16.387  1.00 73.99  ? 443 LYS C O   1 
ATOM   4710  C CB  . LYS C 1 236 ? -79.228  15.376  13.442  1.00 63.89  ? 443 LYS C CB  1 
ATOM   4711  N N   . ASP C 1 237 ? -77.818  13.408  15.691  1.00 69.96  ? 444 ASP C N   1 
ATOM   4712  C CA  . ASP C 1 237 ? -78.004  12.115  16.353  1.00 60.69  ? 444 ASP C CA  1 
ATOM   4713  C C   . ASP C 1 237 ? -76.716  11.664  17.025  1.00 61.18  ? 444 ASP C C   1 
ATOM   4714  O O   . ASP C 1 237 ? -75.973  10.833  16.493  1.00 60.02  ? 444 ASP C O   1 
ATOM   4715  C CB  . ASP C 1 237 ? -78.488  11.055  15.363  1.00 53.86  ? 444 ASP C CB  1 
ATOM   4716  C CG  . ASP C 1 237 ? -78.857  9.745   16.050  1.00 62.42  ? 444 ASP C CG  1 
ATOM   4717  O OD1 . ASP C 1 237 ? -78.745  9.687   17.297  1.00 60.14  ? 444 ASP C OD1 1 
ATOM   4718  O OD2 . ASP C 1 237 ? -79.265  8.778   15.355  1.00 56.45  ? 444 ASP C OD2 1 
ATOM   4719  N N   . PRO C 1 238 ? -76.445  12.153  18.227  1.00 61.99  ? 445 PRO C N   1 
ATOM   4720  C CA  . PRO C 1 238 ? -75.251  11.706  18.950  1.00 61.08  ? 445 PRO C CA  1 
ATOM   4721  C C   . PRO C 1 238 ? -75.355  10.234  19.299  1.00 60.96  ? 445 PRO C C   1 
ATOM   4722  O O   . PRO C 1 238 ? -76.436  9.643   19.314  1.00 66.80  ? 445 PRO C O   1 
ATOM   4723  C CB  . PRO C 1 238 ? -75.245  12.567  20.220  1.00 60.94  ? 445 PRO C CB  1 
ATOM   4724  C CG  . PRO C 1 238 ? -76.324  13.591  20.020  1.00 70.07  ? 445 PRO C CG  1 
ATOM   4725  C CD  . PRO C 1 238 ? -77.306  12.992  19.065  1.00 59.11  ? 445 PRO C CD  1 
ATOM   4726  N N   . ALA C 1 239 ? -74.206  9.637   19.584  1.00 59.23  ? 446 ALA C N   1 
ATOM   4727  C CA  . ALA C 1 239 ? -74.163  8.224   19.956  1.00 51.11  ? 446 ALA C CA  1 
ATOM   4728  C C   . ALA C 1 239 ? -74.174  8.084   21.475  1.00 52.89  ? 446 ALA C C   1 
ATOM   4729  O O   . ALA C 1 239 ? -73.244  7.569   22.094  1.00 53.66  ? 446 ALA C O   1 
ATOM   4730  C CB  . ALA C 1 239 ? -72.944  7.552   19.348  1.00 46.53  ? 446 ALA C CB  1 
ATOM   4731  N N   . ASN C 1 240 ? -75.268  8.568   22.064  1.00 56.48  ? 447 ASN C N   1 
ATOM   4732  C CA  . ASN C 1 240 ? -75.469  8.452   23.529  1.00 55.06  ? 447 ASN C CA  1 
ATOM   4733  C C   . ASN C 1 240 ? -76.281  7.183   23.733  1.00 49.88  ? 447 ASN C C   1 
ATOM   4734  O O   . ASN C 1 240 ? -77.306  7.037   23.063  1.00 52.82  ? 447 ASN C O   1 
ATOM   4735  C CB  . ASN C 1 240 ? -76.161  9.687   24.098  1.00 54.11  ? 447 ASN C CB  1 
ATOM   4736  C CG  . ASN C 1 240 ? -75.286  10.921  24.092  1.00 53.59  ? 447 ASN C CG  1 
ATOM   4737  O OD1 . ASN C 1 240 ? -74.103  10.852  24.407  1.00 54.22  ? 447 ASN C OD1 1 
ATOM   4738  N ND2 . ASN C 1 240 ? -75.863  12.057  23.742  1.00 55.88  ? 447 ASN C ND2 1 
ATOM   4739  N N   . TYR C 1 241 ? -75.827  6.292   24.608  1.00 52.93  ? 448 TYR C N   1 
ATOM   4740  C CA  . TYR C 1 241 ? -76.491  4.972   24.720  1.00 50.49  ? 448 TYR C CA  1 
ATOM   4741  C C   . TYR C 1 241 ? -77.037  4.748   26.124  1.00 51.27  ? 448 TYR C C   1 
ATOM   4742  O O   . TYR C 1 241 ? -76.412  5.187   27.084  1.00 55.61  ? 448 TYR C O   1 
ATOM   4743  C CB  . TYR C 1 241 ? -75.523  3.873   24.278  1.00 49.06  ? 448 TYR C CB  1 
ATOM   4744  C CG  . TYR C 1 241 ? -75.468  3.687   22.787  1.00 46.13  ? 448 TYR C CG  1 
ATOM   4745  C CD1 . TYR C 1 241 ? -74.746  4.555   21.990  1.00 43.70  ? 448 TYR C CD1 1 
ATOM   4746  C CD2 . TYR C 1 241 ? -76.155  2.658   22.173  1.00 43.67  ? 448 TYR C CD2 1 
ATOM   4747  C CE1 . TYR C 1 241 ? -74.707  4.412   20.617  1.00 42.01  ? 448 TYR C CE1 1 
ATOM   4748  C CE2 . TYR C 1 241 ? -76.122  2.494   20.800  1.00 44.81  ? 448 TYR C CE2 1 
ATOM   4749  C CZ  . TYR C 1 241 ? -75.398  3.377   20.024  1.00 45.66  ? 448 TYR C CZ  1 
ATOM   4750  O OH  . TYR C 1 241 ? -75.363  3.243   18.674  1.00 46.60  ? 448 TYR C OH  1 
ATOM   4751  N N   . ILE C 1 242 ? -78.188  4.088   26.206  1.00 52.93  ? 449 ILE C N   1 
ATOM   4752  C CA  . ILE C 1 242 ? -78.839  3.805   27.512  1.00 52.22  ? 449 ILE C CA  1 
ATOM   4753  C C   . ILE C 1 242 ? -78.719  2.314   27.795  1.00 52.63  ? 449 ILE C C   1 
ATOM   4754  O O   . ILE C 1 242 ? -79.157  1.524   26.956  1.00 49.72  ? 449 ILE C O   1 
ATOM   4755  C CB  . ILE C 1 242 ? -80.311  4.252   27.496  1.00 53.51  ? 449 ILE C CB  1 
ATOM   4756  C CG1 . ILE C 1 242 ? -80.489  5.621   26.835  1.00 61.72  ? 449 ILE C CG1 1 
ATOM   4757  C CG2 . ILE C 1 242 ? -80.894  4.231   28.899  1.00 58.53  ? 449 ILE C CG2 1 
ATOM   4758  C CD1 . ILE C 1 242 ? -79.986  6.775   27.668  1.00 72.26  ? 449 ILE C CD1 1 
ATOM   4759  N N   . LEU C 1 243 ? -78.158  1.959   28.948  1.00 52.95  ? 450 LEU C N   1 
ATOM   4760  C CA  . LEU C 1 243 ? -78.026  0.567   29.365  1.00 46.70  ? 450 LEU C CA  1 
ATOM   4761  C C   . LEU C 1 243 ? -79.384  -0.114  29.407  1.00 50.03  ? 450 LEU C C   1 
ATOM   4762  O O   . LEU C 1 243 ? -80.330  0.391   30.015  1.00 51.60  ? 450 LEU C O   1 
ATOM   4763  C CB  . LEU C 1 243 ? -77.364  0.506   30.731  1.00 45.58  ? 450 LEU C CB  1 
ATOM   4764  C CG  . LEU C 1 243 ? -77.090  -0.883  31.281  1.00 48.62  ? 450 LEU C CG  1 
ATOM   4765  C CD1 . LEU C 1 243 ? -76.276  -1.653  30.278  1.00 53.47  ? 450 LEU C CD1 1 
ATOM   4766  C CD2 . LEU C 1 243 ? -76.347  -0.765  32.579  1.00 48.20  ? 450 LEU C CD2 1 
ATOM   4767  N N   . HIS C 1 244 ? -79.480  -1.254  28.738  1.00 51.01  ? 451 HIS C N   1 
ATOM   4768  C CA  . HIS C 1 244 ? -80.667  -2.102  28.768  1.00 53.50  ? 451 HIS C CA  1 
ATOM   4769  C C   . HIS C 1 244 ? -80.441  -3.315  29.660  1.00 56.06  ? 451 HIS C C   1 
ATOM   4770  O O   . HIS C 1 244 ? -81.070  -3.439  30.709  1.00 62.37  ? 451 HIS C O   1 
ATOM   4771  C CB  . HIS C 1 244 ? -81.028  -2.539  27.340  1.00 51.68  ? 451 HIS C CB  1 
ATOM   4772  C CG  . HIS C 1 244 ? -82.437  -3.015  27.166  1.00 51.94  ? 451 HIS C CG  1 
ATOM   4773  N ND1 . HIS C 1 244 ? -82.742  -4.208  26.545  1.00 59.13  ? 451 HIS C ND1 1 
ATOM   4774  C CD2 . HIS C 1 244 ? -83.623  -2.428  27.449  1.00 56.99  ? 451 HIS C CD2 1 
ATOM   4775  C CE1 . HIS C 1 244 ? -84.054  -4.351  26.484  1.00 57.69  ? 451 HIS C CE1 1 
ATOM   4776  N NE2 . HIS C 1 244 ? -84.612  -3.283  27.023  1.00 51.65  ? 451 HIS C NE2 1 
ATOM   4777  N N   . ALA C 1 245 ? -79.511  -4.166  29.241  1.00 53.19  ? 452 ALA C N   1 
ATOM   4778  C CA  . ALA C 1 245 ? -79.304  -5.432  29.963  1.00 51.73  ? 452 ALA C CA  1 
ATOM   4779  C C   . ALA C 1 245 ? -77.872  -5.620  30.441  1.00 58.22  ? 452 ALA C C   1 
ATOM   4780  O O   . ALA C 1 245 ? -76.956  -5.074  29.818  1.00 59.49  ? 452 ALA C O   1 
ATOM   4781  C CB  . ALA C 1 245 ? -79.683  -6.568  29.066  1.00 49.49  ? 452 ALA C CB  1 
ATOM   4782  N N   . VAL C 1 246 ? -77.713  -6.376  31.522  1.00 54.99  ? 453 VAL C N   1 
ATOM   4783  C CA  . VAL C 1 246 ? -76.373  -6.732  32.056  1.00 51.62  ? 453 VAL C CA  1 
ATOM   4784  C C   . VAL C 1 246 ? -76.392  -8.254  32.191  1.00 59.25  ? 453 VAL C C   1 
ATOM   4785  O O   . VAL C 1 246 ? -76.931  -8.744  33.185  1.00 61.33  ? 453 VAL C O   1 
ATOM   4786  C CB  . VAL C 1 246 ? -76.104  -6.041  33.403  1.00 52.51  ? 453 VAL C CB  1 
ATOM   4787  C CG1 . VAL C 1 246 ? -74.719  -6.331  33.938  1.00 51.88  ? 453 VAL C CG1 1 
ATOM   4788  C CG2 . VAL C 1 246 ? -76.349  -4.544  33.359  1.00 52.57  ? 453 VAL C CG2 1 
ATOM   4789  N N   . LEU C 1 247 ? -75.919  -8.970  31.175  1.00 52.72  ? 454 LEU C N   1 
ATOM   4790  C CA  . LEU C 1 247 ? -75.862  -10.450 31.220  1.00 46.67  ? 454 LEU C CA  1 
ATOM   4791  C C   . LEU C 1 247 ? -74.701  -10.819 32.132  1.00 53.81  ? 454 LEU C C   1 
ATOM   4792  O O   . LEU C 1 247 ? -73.574  -10.434 31.828  1.00 56.20  ? 454 LEU C O   1 
ATOM   4793  C CB  . LEU C 1 247 ? -75.765  -10.996 29.795  1.00 52.05  ? 454 LEU C CB  1 
ATOM   4794  C CG  . LEU C 1 247 ? -77.039  -10.818 28.969  1.00 60.57  ? 454 LEU C CG  1 
ATOM   4795  C CD1 . LEU C 1 247 ? -76.959  -9.601  28.063  1.00 50.36  ? 454 LEU C CD1 1 
ATOM   4796  C CD2 . LEU C 1 247 ? -77.348  -12.060 28.158  1.00 55.47  ? 454 LEU C CD2 1 
ATOM   4797  N N   . VAL C 1 248 ? -74.975  -11.581 33.185  1.00 60.12  ? 455 VAL C N   1 
ATOM   4798  C CA  . VAL C 1 248 ? -74.007  -11.820 34.244  1.00 55.78  ? 455 VAL C CA  1 
ATOM   4799  C C   . VAL C 1 248 ? -73.650  -13.295 34.246  1.00 60.22  ? 455 VAL C C   1 
ATOM   4800  O O   . VAL C 1 248 ? -74.505  -14.159 34.000  1.00 60.93  ? 455 VAL C O   1 
ATOM   4801  C CB  . VAL C 1 248 ? -74.552  -11.369 35.612  1.00 56.50  ? 455 VAL C CB  1 
ATOM   4802  C CG1 . VAL C 1 248 ? -73.553  -11.615 36.673  1.00 61.02  ? 455 VAL C CG1 1 
ATOM   4803  C CG2 . VAL C 1 248 ? -74.905  -9.877  35.587  1.00 55.43  ? 455 VAL C CG2 1 
ATOM   4804  N N   . HIS C 1 249 ? -72.370  -13.570 34.476  1.00 54.32  ? 456 HIS C N   1 
ATOM   4805  C CA  . HIS C 1 249 ? -71.835  -14.914 34.565  1.00 60.04  ? 456 HIS C CA  1 
ATOM   4806  C C   . HIS C 1 249 ? -71.110  -15.072 35.892  1.00 68.49  ? 456 HIS C C   1 
ATOM   4807  O O   . HIS C 1 249 ? -70.326  -14.198 36.297  1.00 68.71  ? 456 HIS C O   1 
ATOM   4808  C CB  . HIS C 1 249 ? -70.873  -15.204 33.398  1.00 63.04  ? 456 HIS C CB  1 
ATOM   4809  C CG  . HIS C 1 249 ? -70.089  -16.475 33.552  1.00 62.40  ? 456 HIS C CG  1 
ATOM   4810  N ND1 . HIS C 1 249 ? -68.905  -16.542 34.252  1.00 54.53  ? 456 HIS C ND1 1 
ATOM   4811  C CD2 . HIS C 1 249 ? -70.320  -17.727 33.087  1.00 63.20  ? 456 HIS C CD2 1 
ATOM   4812  C CE1 . HIS C 1 249 ? -68.441  -17.778 34.215  1.00 62.25  ? 456 HIS C CE1 1 
ATOM   4813  N NE2 . HIS C 1 249 ? -69.280  -18.517 33.513  1.00 62.04  ? 456 HIS C NE2 1 
ATOM   4814  N N   . SER C 1 250 ? -71.362  -16.191 36.572  1.00 70.22  ? 457 SER C N   1 
ATOM   4815  C CA  . SER C 1 250 ? -70.610  -16.516 37.777  1.00 72.24  ? 457 SER C CA  1 
ATOM   4816  C C   . SER C 1 250 ? -70.019  -17.910 37.675  1.00 67.26  ? 457 SER C C   1 
ATOM   4817  O O   . SER C 1 250 ? -70.683  -18.838 37.204  1.00 66.49  ? 457 SER C O   1 
ATOM   4818  C CB  . SER C 1 250 ? -71.476  -16.440 39.017  1.00 70.71  ? 457 SER C CB  1 
ATOM   4819  O OG  . SER C 1 250 ? -70.663  -16.359 40.180  1.00 80.49  ? 457 SER C OG  1 
ATOM   4820  N N   . GLY C 1 251 ? -68.776  -18.046 38.138  1.00 68.06  ? 458 GLY C N   1 
ATOM   4821  C CA  . GLY C 1 251 ? -68.081  -19.318 38.113  1.00 75.97  ? 458 GLY C CA  1 
ATOM   4822  C C   . GLY C 1 251 ? -66.645  -19.236 37.630  1.00 80.44  ? 458 GLY C C   1 
ATOM   4823  O O   . GLY C 1 251 ? -65.932  -18.267 37.916  1.00 77.33  ? 458 GLY C O   1 
ATOM   4824  N N   . ASP C 1 252 ? -66.208  -20.276 36.921  1.00 85.84  ? 459 ASP C N   1 
ATOM   4825  C CA  . ASP C 1 252 ? -64.896  -20.362 36.290  1.00 89.05  ? 459 ASP C CA  1 
ATOM   4826  C C   . ASP C 1 252 ? -65.073  -20.418 34.768  1.00 94.37  ? 459 ASP C C   1 
ATOM   4827  O O   . ASP C 1 252 ? -66.139  -20.086 34.232  1.00 91.31  ? 459 ASP C O   1 
ATOM   4828  C CB  . ASP C 1 252 ? -64.125  -21.575 36.818  1.00 94.50  ? 459 ASP C CB  1 
ATOM   4829  C CG  . ASP C 1 252 ? -64.716  -22.884 36.350  1.00 100.56 ? 459 ASP C CG  1 
ATOM   4830  O OD1 . ASP C 1 252 ? -65.641  -23.400 37.023  1.00 101.20 ? 459 ASP C OD1 1 
ATOM   4831  O OD2 . ASP C 1 252 ? -64.265  -23.378 35.291  1.00 100.19 ? 459 ASP C OD2 1 
ATOM   4832  N N   . ASN C 1 253 ? -64.018  -20.850 34.063  1.00 96.44  ? 460 ASN C N   1 
ATOM   4833  C CA  . ASN C 1 253 ? -64.074  -20.854 32.601  1.00 94.57  ? 460 ASN C CA  1 
ATOM   4834  C C   . ASN C 1 253 ? -64.996  -21.956 32.095  1.00 99.10  ? 460 ASN C C   1 
ATOM   4835  O O   . ASN C 1 253 ? -65.876  -21.705 31.258  1.00 87.69  ? 460 ASN C O   1 
ATOM   4836  C CB  . ASN C 1 253 ? -62.670  -20.998 32.008  1.00 86.35  ? 460 ASN C CB  1 
ATOM   4837  N N   . HIS C 1 254 ? -64.830  -23.175 32.617  1.00 110.99 ? 461 HIS C N   1 
ATOM   4838  C CA  . HIS C 1 254 ? -65.643  -24.325 32.230  1.00 119.90 ? 461 HIS C CA  1 
ATOM   4839  C C   . HIS C 1 254 ? -66.684  -24.552 33.323  1.00 110.41 ? 461 HIS C C   1 
ATOM   4840  O O   . HIS C 1 254 ? -66.416  -25.207 34.329  1.00 112.34 ? 461 HIS C O   1 
ATOM   4841  C CB  . HIS C 1 254 ? -64.770  -25.557 32.015  1.00 126.66 ? 461 HIS C CB  1 
ATOM   4842  N N   . GLY C 1 255 ? -67.883  -23.991 33.122  1.00 93.00  ? 462 GLY C N   1 
ATOM   4843  C CA  . GLY C 1 255 ? -69.005  -24.173 34.035  1.00 92.15  ? 462 GLY C CA  1 
ATOM   4844  C C   . GLY C 1 255 ? -69.327  -23.008 34.962  1.00 85.25  ? 462 GLY C C   1 
ATOM   4845  O O   . GLY C 1 255 ? -68.423  -22.380 35.526  1.00 86.99  ? 462 GLY C O   1 
ATOM   4846  N N   . GLY C 1 256 ? -70.616  -22.723 35.143  1.00 72.22  ? 463 GLY C N   1 
ATOM   4847  C CA  . GLY C 1 256 ? -71.033  -21.622 35.996  1.00 63.46  ? 463 GLY C CA  1 
ATOM   4848  C C   . GLY C 1 256 ? -72.508  -21.316 35.792  1.00 62.18  ? 463 GLY C C   1 
ATOM   4849  O O   . GLY C 1 256 ? -73.240  -22.129 35.226  1.00 63.49  ? 463 GLY C O   1 
ATOM   4850  N N   . HIS C 1 257 ? -72.964  -20.148 36.248  1.00 61.46  ? 464 HIS C N   1 
ATOM   4851  C CA  . HIS C 1 257 ? -74.414  -19.816 36.150  1.00 63.62  ? 464 HIS C CA  1 
ATOM   4852  C C   . HIS C 1 257 ? -74.655  -18.506 35.393  1.00 64.63  ? 464 HIS C C   1 
ATOM   4853  O O   . HIS C 1 257 ? -73.800  -17.611 35.483  1.00 62.65  ? 464 HIS C O   1 
ATOM   4854  C CB  . HIS C 1 257 ? -75.071  -19.783 37.529  1.00 54.46  ? 464 HIS C CB  1 
ATOM   4855  C CG  . HIS C 1 257 ? -76.543  -19.976 37.451  1.00 56.10  ? 464 HIS C CG  1 
ATOM   4856  N ND1 . HIS C 1 257 ? -77.098  -21.132 36.952  1.00 58.82  ? 464 HIS C ND1 1 
ATOM   4857  C CD2 . HIS C 1 257 ? -77.570  -19.160 37.762  1.00 57.28  ? 464 HIS C CD2 1 
ATOM   4858  C CE1 . HIS C 1 257 ? -78.407  -21.031 36.978  1.00 64.49  ? 464 HIS C CE1 1 
ATOM   4859  N NE2 . HIS C 1 257 ? -78.718  -19.834 37.468  1.00 56.29  ? 464 HIS C NE2 1 
ATOM   4860  N N   . TYR C 1 258 ? -75.799  -18.401 34.706  1.00 59.96  ? 465 TYR C N   1 
ATOM   4861  C CA  . TYR C 1 258 ? -76.084  -17.203 33.876  1.00 61.59  ? 465 TYR C CA  1 
ATOM   4862  C C   . TYR C 1 258 ? -77.349  -16.487 34.325  1.00 58.91  ? 465 TYR C C   1 
ATOM   4863  O O   . TYR C 1 258 ? -78.393  -17.137 34.452  1.00 61.49  ? 465 TYR C O   1 
ATOM   4864  C CB  . TYR C 1 258 ? -76.193  -17.563 32.397  1.00 61.72  ? 465 TYR C CB  1 
ATOM   4865  C CG  . TYR C 1 258 ? -74.938  -17.344 31.597  1.00 60.73  ? 465 TYR C CG  1 
ATOM   4866  C CD1 . TYR C 1 258 ? -74.421  -16.076 31.417  1.00 61.41  ? 465 TYR C CD1 1 
ATOM   4867  C CD2 . TYR C 1 258 ? -74.275  -18.406 31.015  1.00 54.22  ? 465 TYR C CD2 1 
ATOM   4868  C CE1 . TYR C 1 258 ? -73.268  -15.866 30.683  1.00 58.09  ? 465 TYR C CE1 1 
ATOM   4869  C CE2 . TYR C 1 258 ? -73.124  -18.215 30.276  1.00 59.17  ? 465 TYR C CE2 1 
ATOM   4870  C CZ  . TYR C 1 258 ? -72.620  -16.941 30.109  1.00 61.78  ? 465 TYR C CZ  1 
ATOM   4871  O OH  . TYR C 1 258 ? -71.489  -16.751 29.376  1.00 61.57  ? 465 TYR C OH  1 
ATOM   4872  N N   . VAL C 1 259 ? -77.249  -15.175 34.498  1.00 61.53  ? 466 VAL C N   1 
ATOM   4873  C CA  . VAL C 1 259 ? -78.343  -14.325 34.948  1.00 59.94  ? 466 VAL C CA  1 
ATOM   4874  C C   . VAL C 1 259 ? -78.338  -13.068 34.077  1.00 60.28  ? 466 VAL C C   1 
ATOM   4875  O O   . VAL C 1 259 ? -77.294  -12.672 33.549  1.00 59.02  ? 466 VAL C O   1 
ATOM   4876  C CB  . VAL C 1 259 ? -78.170  -13.992 36.456  1.00 53.48  ? 466 VAL C CB  1 
ATOM   4877  C CG1 . VAL C 1 259 ? -78.793  -12.662 36.840  1.00 59.47  ? 466 VAL C CG1 1 
ATOM   4878  C CG2 . VAL C 1 259 ? -78.736  -15.091 37.307  1.00 51.24  ? 466 VAL C CG2 1 
ATOM   4879  N N   . VAL C 1 260 ? -79.514  -12.466 33.892  1.00 51.06  ? 467 VAL C N   1 
ATOM   4880  C CA  . VAL C 1 260 ? -79.599  -11.182 33.146  1.00 56.70  ? 467 VAL C CA  1 
ATOM   4881  C C   . VAL C 1 260 ? -80.333  -10.129 33.980  1.00 61.26  ? 467 VAL C C   1 
ATOM   4882  O O   . VAL C 1 260 ? -81.349  -10.460 34.601  1.00 64.58  ? 467 VAL C O   1 
ATOM   4883  C CB  . VAL C 1 260 ? -80.252  -11.368 31.764  1.00 59.97  ? 467 VAL C CB  1 
ATOM   4884  C CG1 . VAL C 1 260 ? -81.654  -11.947 31.830  1.00 60.23  ? 467 VAL C CG1 1 
ATOM   4885  C CG2 . VAL C 1 260 ? -80.221  -10.094 30.941  1.00 58.91  ? 467 VAL C CG2 1 
ATOM   4886  N N   . TYR C 1 261 ? -79.783  -8.921  34.059  1.00 62.36  ? 468 TYR C N   1 
ATOM   4887  C CA  . TYR C 1 261 ? -80.494  -7.801  34.711  1.00 61.24  ? 468 TYR C CA  1 
ATOM   4888  C C   . TYR C 1 261 ? -81.037  -6.940  33.573  1.00 61.41  ? 468 TYR C C   1 
ATOM   4889  O O   . TYR C 1 261 ? -80.288  -6.718  32.635  1.00 64.37  ? 468 TYR C O   1 
ATOM   4890  C CB  . TYR C 1 261 ? -79.541  -7.055  35.636  1.00 59.27  ? 468 TYR C CB  1 
ATOM   4891  C CG  . TYR C 1 261 ? -79.059  -7.795  36.857  1.00 66.06  ? 468 TYR C CG  1 
ATOM   4892  C CD1 . TYR C 1 261 ? -78.033  -8.716  36.778  1.00 59.46  ? 468 TYR C CD1 1 
ATOM   4893  C CD2 . TYR C 1 261 ? -79.593  -7.535  38.105  1.00 69.46  ? 468 TYR C CD2 1 
ATOM   4894  C CE1 . TYR C 1 261 ? -77.571  -9.379  37.900  1.00 70.67  ? 468 TYR C CE1 1 
ATOM   4895  C CE2 . TYR C 1 261 ? -79.133  -8.175  39.241  1.00 62.26  ? 468 TYR C CE2 1 
ATOM   4896  C CZ  . TYR C 1 261 ? -78.121  -9.108  39.136  1.00 70.50  ? 468 TYR C CZ  1 
ATOM   4897  O OH  . TYR C 1 261 ? -77.658  -9.761  40.239  1.00 75.58  ? 468 TYR C OH  1 
ATOM   4898  N N   . LEU C 1 262 ? -82.270  -6.455  33.660  1.00 53.42  ? 469 LEU C N   1 
ATOM   4899  C CA  . LEU C 1 262 ? -82.927  -5.742  32.586  1.00 53.68  ? 469 LEU C CA  1 
ATOM   4900  C C   . LEU C 1 262 ? -83.815  -4.671  33.189  1.00 64.44  ? 469 LEU C C   1 
ATOM   4901  O O   . LEU C 1 262 ? -84.516  -4.931  34.167  1.00 68.29  ? 469 LEU C O   1 
ATOM   4902  C CB  . LEU C 1 262 ? -83.780  -6.705  31.729  1.00 62.29  ? 469 LEU C CB  1 
ATOM   4903  C CG  . LEU C 1 262 ? -83.165  -7.601  30.637  1.00 62.12  ? 469 LEU C CG  1 
ATOM   4904  C CD1 . LEU C 1 262 ? -83.801  -8.984  30.641  1.00 56.62  ? 469 LEU C CD1 1 
ATOM   4905  C CD2 . LEU C 1 262 ? -83.330  -6.967  29.251  1.00 56.38  ? 469 LEU C CD2 1 
ATOM   4906  N N   . ASN C 1 263 ? -83.771  -3.460  32.626  1.00 66.17  ? 470 ASN C N   1 
ATOM   4907  C CA  . ASN C 1 263 ? -84.870  -2.515  32.807  1.00 66.10  ? 470 ASN C CA  1 
ATOM   4908  C C   . ASN C 1 263 ? -85.638  -2.471  31.490  1.00 66.42  ? 470 ASN C C   1 
ATOM   4909  O O   . ASN C 1 263 ? -85.367  -1.627  30.620  1.00 63.55  ? 470 ASN C O   1 
ATOM   4910  C CB  . ASN C 1 263 ? -84.404  -1.122  33.242  1.00 66.03  ? 470 ASN C CB  1 
ATOM   4911  C CG  . ASN C 1 263 ? -83.436  -0.501  32.289  1.00 65.63  ? 470 ASN C CG  1 
ATOM   4912  O OD1 . ASN C 1 263 ? -82.464  -1.131  31.890  1.00 66.70  ? 470 ASN C OD1 1 
ATOM   4913  N ND2 . ASN C 1 263 ? -83.689  0.756   31.920  1.00 64.44  ? 470 ASN C ND2 1 
ATOM   4914  N N   . PRO C 1 264 ? -86.606  -3.371  31.301  1.00 62.89  ? 471 PRO C N   1 
ATOM   4915  C CA  . PRO C 1 264 ? -87.171  -3.592  29.961  1.00 63.28  ? 471 PRO C CA  1 
ATOM   4916  C C   . PRO C 1 264 ? -87.810  -2.366  29.334  1.00 63.51  ? 471 PRO C C   1 
ATOM   4917  O O   . PRO C 1 264 ? -87.819  -2.264  28.104  1.00 67.36  ? 471 PRO C O   1 
ATOM   4918  C CB  . PRO C 1 264 ? -88.202  -4.703  30.206  1.00 60.20  ? 471 PRO C CB  1 
ATOM   4919  C CG  . PRO C 1 264 ? -87.758  -5.372  31.444  1.00 61.39  ? 471 PRO C CG  1 
ATOM   4920  C CD  . PRO C 1 264 ? -87.087  -4.348  32.283  1.00 55.83  ? 471 PRO C CD  1 
ATOM   4921  N N   . LYS C 1 265 ? -88.363  -1.445  30.124  1.00 71.42  ? 472 LYS C N   1 
ATOM   4922  C CA  . LYS C 1 265 ? -88.973  -0.241  29.573  1.00 67.95  ? 472 LYS C CA  1 
ATOM   4923  C C   . LYS C 1 265 ? -87.956  0.858   29.306  1.00 71.44  ? 472 LYS C C   1 
ATOM   4924  O O   . LYS C 1 265 ? -88.318  1.891   28.726  1.00 75.39  ? 472 LYS C O   1 
ATOM   4925  C CB  . LYS C 1 265 ? -90.063  0.283   30.515  1.00 70.18  ? 472 LYS C CB  1 
ATOM   4926  N N   . GLY C 1 266 ? -86.700  0.658   29.704  1.00 71.30  ? 473 GLY C N   1 
ATOM   4927  C CA  . GLY C 1 266 ? -85.689  1.686   29.563  1.00 64.83  ? 473 GLY C CA  1 
ATOM   4928  C C   . GLY C 1 266 ? -85.815  2.817   30.550  1.00 74.44  ? 473 GLY C C   1 
ATOM   4929  O O   . GLY C 1 266 ? -85.234  3.882   30.336  1.00 80.51  ? 473 GLY C O   1 
ATOM   4930  N N   . ASP C 1 267 ? -86.562  2.621   31.637  1.00 76.63  ? 474 ASP C N   1 
ATOM   4931  C CA  . ASP C 1 267 ? -86.853  3.691   32.583  1.00 71.82  ? 474 ASP C CA  1 
ATOM   4932  C C   . ASP C 1 267 ? -86.213  3.454   33.945  1.00 70.19  ? 474 ASP C C   1 
ATOM   4933  O O   . ASP C 1 267 ? -86.766  3.855   34.965  1.00 79.77  ? 474 ASP C O   1 
ATOM   4934  C CB  . ASP C 1 267 ? -88.367  3.893   32.728  1.00 74.73  ? 474 ASP C CB  1 
ATOM   4935  C CG  . ASP C 1 267 ? -89.119  2.638   33.213  1.00 79.74  ? 474 ASP C CG  1 
ATOM   4936  O OD1 . ASP C 1 267 ? -88.495  1.621   33.618  1.00 75.29  ? 474 ASP C OD1 1 
ATOM   4937  O OD2 . ASP C 1 267 ? -90.373  2.698   33.199  1.00 77.67  ? 474 ASP C OD2 1 
ATOM   4938  N N   . GLY C 1 268 ? -85.054  2.809   33.986  1.00 65.71  ? 475 GLY C N   1 
ATOM   4939  C CA  . GLY C 1 268 ? -84.392  2.599   35.257  1.00 61.93  ? 475 GLY C CA  1 
ATOM   4940  C C   . GLY C 1 268 ? -85.130  1.719   36.249  1.00 62.42  ? 475 GLY C C   1 
ATOM   4941  O O   . GLY C 1 268 ? -84.684  1.554   37.385  1.00 59.72  ? 475 GLY C O   1 
ATOM   4942  N N   . LYS C 1 269 ? -86.254  1.138   35.837  1.00 71.92  ? 476 LYS C N   1 
ATOM   4943  C CA  . LYS C 1 269 ? -87.009  0.214   36.686  1.00 75.72  ? 476 LYS C CA  1 
ATOM   4944  C C   . LYS C 1 269 ? -86.466  -1.193  36.442  1.00 69.64  ? 476 LYS C C   1 
ATOM   4945  O O   . LYS C 1 269 ? -86.910  -1.905  35.541  1.00 68.64  ? 476 LYS C O   1 
ATOM   4946  C CB  . LYS C 1 269 ? -88.504  0.315   36.393  1.00 67.18  ? 476 LYS C CB  1 
ATOM   4947  N N   . TRP C 1 270 ? -85.506  -1.606  37.271  1.00 63.84  ? 477 TRP C N   1 
ATOM   4948  C CA  . TRP C 1 270 ? -84.737  -2.825  37.052  1.00 69.59  ? 477 TRP C CA  1 
ATOM   4949  C C   . TRP C 1 270 ? -85.312  -4.048  37.758  1.00 71.08  ? 477 TRP C C   1 
ATOM   4950  O O   . TRP C 1 270 ? -85.810  -3.972  38.885  1.00 72.59  ? 477 TRP C O   1 
ATOM   4951  C CB  . TRP C 1 270 ? -83.294  -2.632  37.532  1.00 67.35  ? 477 TRP C CB  1 
ATOM   4952  C CG  . TRP C 1 270 ? -82.452  -1.812  36.587  1.00 71.48  ? 477 TRP C CG  1 
ATOM   4953  C CD1 . TRP C 1 270 ? -82.384  -0.443  36.498  1.00 63.78  ? 477 TRP C CD1 1 
ATOM   4954  C CD2 . TRP C 1 270 ? -81.564  -2.323  35.584  1.00 68.37  ? 477 TRP C CD2 1 
ATOM   4955  N NE1 . TRP C 1 270 ? -81.504  -0.083  35.502  1.00 66.09  ? 477 TRP C NE1 1 
ATOM   4956  C CE2 . TRP C 1 270 ? -80.990  -1.219  34.928  1.00 67.65  ? 477 TRP C CE2 1 
ATOM   4957  C CE3 . TRP C 1 270 ? -81.215  -3.607  35.171  1.00 61.29  ? 477 TRP C CE3 1 
ATOM   4958  C CZ2 . TRP C 1 270 ? -80.083  -1.371  33.888  1.00 63.46  ? 477 TRP C CZ2 1 
ATOM   4959  C CZ3 . TRP C 1 270 ? -80.309  -3.751  34.168  1.00 61.79  ? 477 TRP C CZ3 1 
ATOM   4960  C CH2 . TRP C 1 270 ? -79.760  -2.649  33.525  1.00 61.30  ? 477 TRP C CH2 1 
ATOM   4961  N N   . CYS C 1 271 ? -85.171  -5.197  37.098  1.00 69.84  ? 478 CYS C N   1 
ATOM   4962  C CA  . CYS C 1 271 ? -85.444  -6.500  37.685  1.00 68.55  ? 478 CYS C CA  1 
ATOM   4963  C C   . CYS C 1 271 ? -84.297  -7.452  37.376  1.00 67.66  ? 478 CYS C C   1 
ATOM   4964  O O   . CYS C 1 271 ? -83.421  -7.166  36.557  1.00 68.77  ? 478 CYS C O   1 
ATOM   4965  C CB  . CYS C 1 271 ? -86.757  -7.106  37.163  1.00 71.23  ? 478 CYS C CB  1 
ATOM   4966  S SG  . CYS C 1 271 ? -88.162  -5.965  36.953  1.00 84.66  ? 478 CYS C SG  1 
ATOM   4967  N N   . LYS C 1 272 ? -84.321  -8.618  38.021  1.00 67.31  ? 479 LYS C N   1 
ATOM   4968  C CA  . LYS C 1 272 ? -83.327  -9.656  37.778  1.00 68.21  ? 479 LYS C CA  1 
ATOM   4969  C C   . LYS C 1 272 ? -83.999  -10.982 37.437  1.00 71.36  ? 479 LYS C C   1 
ATOM   4970  O O   . LYS C 1 272 ? -84.882  -11.446 38.167  1.00 76.18  ? 479 LYS C O   1 
ATOM   4971  C CB  . LYS C 1 272 ? -82.406  -9.834  38.980  1.00 69.31  ? 479 LYS C CB  1 
ATOM   4972  C CG  . LYS C 1 272 ? -81.409  -10.941 38.767  1.00 65.99  ? 479 LYS C CG  1 
ATOM   4973  C CD  . LYS C 1 272 ? -81.445  -11.935 39.895  1.00 69.23  ? 479 LYS C CD  1 
ATOM   4974  C CE  . LYS C 1 272 ? -80.345  -11.629 40.904  1.00 72.21  ? 479 LYS C CE  1 
ATOM   4975  N NZ  . LYS C 1 272 ? -80.158  -12.697 41.918  1.00 70.51  ? 479 LYS C NZ  1 
ATOM   4976  N N   . PHE C 1 273 ? -83.538  -11.609 36.350  1.00 67.98  ? 480 PHE C N   1 
ATOM   4977  C CA  . PHE C 1 273 ? -84.123  -12.823 35.779  1.00 64.39  ? 480 PHE C CA  1 
ATOM   4978  C C   . PHE C 1 273 ? -83.148  -13.981 35.971  1.00 69.01  ? 480 PHE C C   1 
ATOM   4979  O O   . PHE C 1 273 ? -82.172  -14.101 35.225  1.00 69.08  ? 480 PHE C O   1 
ATOM   4980  C CB  . PHE C 1 273 ? -84.422  -12.644 34.291  1.00 62.26  ? 480 PHE C CB  1 
ATOM   4981  C CG  . PHE C 1 273 ? -85.356  -11.505 33.971  1.00 61.92  ? 480 PHE C CG  1 
ATOM   4982  C CD1 . PHE C 1 273 ? -84.954  -10.189 34.137  1.00 54.02  ? 480 PHE C CD1 1 
ATOM   4983  C CD2 . PHE C 1 273 ? -86.632  -11.758 33.466  1.00 58.40  ? 480 PHE C CD2 1 
ATOM   4984  C CE1 . PHE C 1 273 ? -85.812  -9.140  33.829  1.00 62.10  ? 480 PHE C CE1 1 
ATOM   4985  C CE2 . PHE C 1 273 ? -87.495  -10.711 33.155  1.00 60.76  ? 480 PHE C CE2 1 
ATOM   4986  C CZ  . PHE C 1 273 ? -87.082  -9.398  33.332  1.00 55.85  ? 480 PHE C CZ  1 
ATOM   4987  N N   . ASP C 1 274 ? -83.423  -14.847 36.949  1.00 70.36  ? 481 ASP C N   1 
ATOM   4988  C CA  . ASP C 1 274 ? -82.667  -16.084 37.169  1.00 60.03  ? 481 ASP C CA  1 
ATOM   4989  C C   . ASP C 1 274 ? -83.601  -17.229 36.793  1.00 69.03  ? 481 ASP C C   1 
ATOM   4990  O O   . ASP C 1 274 ? -84.248  -17.833 37.648  1.00 78.12  ? 481 ASP C O   1 
ATOM   4991  C CB  . ASP C 1 274 ? -82.185  -16.199 38.620  1.00 54.32  ? 481 ASP C CB  1 
ATOM   4992  C CG  . ASP C 1 274 ? -81.100  -17.247 38.810  1.00 63.22  ? 481 ASP C CG  1 
ATOM   4993  O OD1 . ASP C 1 274 ? -80.903  -18.090 37.913  1.00 63.16  ? 481 ASP C OD1 1 
ATOM   4994  O OD2 . ASP C 1 274 ? -80.435  -17.226 39.878  1.00 65.96  ? 481 ASP C OD2 1 
ATOM   4995  N N   . ASP C 1 275 ? -83.638  -17.535 35.505  1.00 67.45  ? 482 ASP C N   1 
ATOM   4996  C CA  . ASP C 1 275 ? -84.507  -18.628 35.010  1.00 71.22  ? 482 ASP C CA  1 
ATOM   4997  C C   . ASP C 1 275 ? -85.952  -18.342 35.439  1.00 75.27  ? 482 ASP C C   1 
ATOM   4998  O O   . ASP C 1 275 ? -86.521  -17.395 34.887  1.00 69.31  ? 482 ASP C O   1 
ATOM   4999  C CB  . ASP C 1 275 ? -83.946  -19.997 35.404  1.00 62.68  ? 482 ASP C CB  1 
ATOM   5000  C CG  . ASP C 1 275 ? -82.493  -20.201 35.022  1.00 67.82  ? 482 ASP C CG  1 
ATOM   5001  O OD1 . ASP C 1 275 ? -82.191  -20.135 33.823  1.00 72.57  ? 482 ASP C OD1 1 
ATOM   5002  O OD2 . ASP C 1 275 ? -81.679  -20.430 35.929  1.00 65.28  ? 482 ASP C OD2 1 
ATOM   5003  N N   . ASP C 1 276 ? -86.515  -19.114 36.373  1.00 75.17  ? 483 ASP C N   1 
ATOM   5004  C CA  . ASP C 1 276 ? -87.945  -18.983 36.776  1.00 75.37  ? 483 ASP C CA  1 
ATOM   5005  C C   . ASP C 1 276 ? -88.143  -17.952 37.884  1.00 73.52  ? 483 ASP C C   1 
ATOM   5006  O O   . ASP C 1 276 ? -89.303  -17.728 38.258  1.00 71.81  ? 483 ASP C O   1 
ATOM   5007  C CB  . ASP C 1 276 ? -88.462  -20.333 37.266  1.00 72.82  ? 483 ASP C CB  1 
ATOM   5008  C CG  . ASP C 1 276 ? -87.552  -21.013 38.273  1.00 76.95  ? 483 ASP C CG  1 
ATOM   5009  O OD1 . ASP C 1 276 ? -86.533  -21.592 37.850  1.00 71.31  ? 483 ASP C OD1 1 
ATOM   5010  O OD2 . ASP C 1 276 ? -87.878  -20.967 39.471  1.00 78.12  ? 483 ASP C OD2 1 
ATOM   5011  N N   . VAL C 1 277 ? -87.073  -17.325 38.359  1.00 69.95  ? 484 VAL C N   1 
ATOM   5012  C CA  . VAL C 1 277 ? -87.136  -16.421 39.509  1.00 72.78  ? 484 VAL C CA  1 
ATOM   5013  C C   . VAL C 1 277 ? -86.922  -14.966 39.088  1.00 72.03  ? 484 VAL C C   1 
ATOM   5014  O O   . VAL C 1 277 ? -85.788  -14.474 39.061  1.00 71.71  ? 484 VAL C O   1 
ATOM   5015  C CB  . VAL C 1 277 ? -86.086  -16.829 40.565  1.00 69.56  ? 484 VAL C CB  1 
ATOM   5016  C CG1 . VAL C 1 277 ? -86.452  -16.282 41.929  1.00 68.56  ? 484 VAL C CG1 1 
ATOM   5017  C CG2 . VAL C 1 277 ? -85.905  -18.340 40.605  1.00 73.63  ? 484 VAL C CG2 1 
ATOM   5018  N N   . VAL C 1 278 ? -87.993  -14.251 38.771  1.00 67.81  ? 485 VAL C N   1 
ATOM   5019  C CA  . VAL C 1 278 ? -87.891  -12.842 38.384  1.00 74.65  ? 485 VAL C CA  1 
ATOM   5020  C C   . VAL C 1 278 ? -88.150  -11.968 39.616  1.00 76.57  ? 485 VAL C C   1 
ATOM   5021  O O   . VAL C 1 278 ? -89.184  -12.114 40.279  1.00 78.04  ? 485 VAL C O   1 
ATOM   5022  C CB  . VAL C 1 278 ? -88.868  -12.507 37.237  1.00 67.55  ? 485 VAL C CB  1 
ATOM   5023  C CG1 . VAL C 1 278 ? -88.658  -11.101 36.743  1.00 68.64  ? 485 VAL C CG1 1 
ATOM   5024  C CG2 . VAL C 1 278 ? -88.697  -13.458 36.085  1.00 65.92  ? 485 VAL C CG2 1 
ATOM   5025  N N   . SER C 1 279 ? -87.195  -11.087 39.929  1.00 71.03  ? 486 SER C N   1 
ATOM   5026  C CA  . SER C 1 279 ? -87.288  -10.261 41.156  1.00 64.31  ? 486 SER C CA  1 
ATOM   5027  C C   . SER C 1 279 ? -86.903  -8.820  40.871  1.00 70.34  ? 486 SER C C   1 
ATOM   5028  O O   . SER C 1 279 ? -85.931  -8.624  40.157  1.00 78.49  ? 486 SER C O   1 
ATOM   5029  C CB  . SER C 1 279 ? -86.368  -10.815 42.197  1.00 68.71  ? 486 SER C CB  1 
ATOM   5030  O OG  . SER C 1 279 ? -86.041  -9.845  43.181  1.00 72.00  ? 486 SER C OG  1 
ATOM   5031  N N   . ARG C 1 280 ? -87.594  -7.856  41.476  1.00 72.07  ? 487 ARG C N   1 
ATOM   5032  C CA  . ARG C 1 280 ? -87.198  -6.459  41.347  1.00 69.24  ? 487 ARG C CA  1 
ATOM   5033  C C   . ARG C 1 280 ? -85.811  -6.280  41.960  1.00 70.40  ? 487 ARG C C   1 
ATOM   5034  O O   . ARG C 1 280 ? -85.361  -7.080  42.777  1.00 65.98  ? 487 ARG C O   1 
ATOM   5035  C CB  . ARG C 1 280 ? -88.212  -5.525  42.010  1.00 51.75  ? 487 ARG C CB  1 
ATOM   5036  N N   . CYS C 1 281 ? -85.108  -5.240  41.527  1.00 72.71  ? 488 CYS C N   1 
ATOM   5037  C CA  . CYS C 1 281 ? -83.743  -5.032  41.986  1.00 69.70  ? 488 CYS C CA  1 
ATOM   5038  C C   . CYS C 1 281 ? -83.402  -3.557  41.825  1.00 68.90  ? 488 CYS C C   1 
ATOM   5039  O O   . CYS C 1 281 ? -84.109  -2.792  41.160  1.00 68.05  ? 488 CYS C O   1 
ATOM   5040  C CB  . CYS C 1 281 ? -82.761  -5.999  41.263  1.00 70.54  ? 488 CYS C CB  1 
ATOM   5041  S SG  . CYS C 1 281 ? -82.172  -5.538  39.613  1.00 71.03  ? 488 CYS C SG  1 
ATOM   5042  N N   . THR C 1 282 ? -82.341  -3.152  42.505  1.00 67.89  ? 489 THR C N   1 
ATOM   5043  C CA  . THR C 1 282 ? -81.886  -1.776  42.432  1.00 72.50  ? 489 THR C CA  1 
ATOM   5044  C C   . THR C 1 282 ? -80.959  -1.589  41.239  1.00 69.45  ? 489 THR C C   1 
ATOM   5045  O O   . THR C 1 282 ? -80.402  -2.548  40.690  1.00 63.59  ? 489 THR C O   1 
ATOM   5046  C CB  . THR C 1 282 ? -81.154  -1.341  43.716  1.00 74.54  ? 489 THR C CB  1 
ATOM   5047  O OG1 . THR C 1 282 ? -80.114  -2.279  44.047  1.00 72.07  ? 489 THR C OG1 1 
ATOM   5048  C CG2 . THR C 1 282 ? -82.132  -1.199  44.880  1.00 68.99  ? 489 THR C CG2 1 
ATOM   5049  N N   . LYS C 1 283 ? -80.819  -0.322  40.834  1.00 68.94  ? 490 LYS C N   1 
ATOM   5050  C CA  . LYS C 1 283 ? -79.746  0.064   39.926  1.00 65.50  ? 490 LYS C CA  1 
ATOM   5051  C C   . LYS C 1 283 ? -78.398  -0.366  40.492  1.00 69.20  ? 490 LYS C C   1 
ATOM   5052  O O   . LYS C 1 283 ? -77.635  -1.083  39.833  1.00 65.74  ? 490 LYS C O   1 
ATOM   5053  C CB  . LYS C 1 283 ? -79.768  1.576   39.684  1.00 67.21  ? 490 LYS C CB  1 
ATOM   5054  C CG  . LYS C 1 283 ? -80.733  2.065   38.609  1.00 61.73  ? 490 LYS C CG  1 
ATOM   5055  C CD  . LYS C 1 283 ? -80.711  3.593   38.522  1.00 59.45  ? 490 LYS C CD  1 
ATOM   5056  C CE  . LYS C 1 283 ? -81.757  4.136   37.530  1.00 65.52  ? 490 LYS C CE  1 
ATOM   5057  N NZ  . LYS C 1 283 ? -81.881  5.645   37.478  1.00 58.40  ? 490 LYS C NZ  1 
ATOM   5058  N N   . GLU C 1 284 ? -78.097  0.047   41.731  1.00 66.19  ? 491 GLU C N   1 
ATOM   5059  C CA  . GLU C 1 284 ? -76.857  -0.391  42.364  1.00 65.88  ? 491 GLU C CA  1 
ATOM   5060  C C   . GLU C 1 284 ? -76.649  -1.892  42.191  1.00 69.04  ? 491 GLU C C   1 
ATOM   5061  O O   . GLU C 1 284 ? -75.524  -2.350  41.962  1.00 68.42  ? 491 GLU C O   1 
ATOM   5062  C CB  . GLU C 1 284 ? -76.850  -0.014  43.849  1.00 65.83  ? 491 GLU C CB  1 
ATOM   5063  N N   . GLU C 1 285 ? -77.731  -2.673  42.253  1.00 70.84  ? 492 GLU C N   1 
ATOM   5064  C CA  . GLU C 1 285 ? -77.604  -4.115  42.069  1.00 72.52  ? 492 GLU C CA  1 
ATOM   5065  C C   . GLU C 1 285 ? -77.214  -4.470  40.636  1.00 72.98  ? 492 GLU C C   1 
ATOM   5066  O O   . GLU C 1 285 ? -76.147  -5.050  40.398  1.00 73.02  ? 492 GLU C O   1 
ATOM   5067  C CB  . GLU C 1 285 ? -78.898  -4.807  42.465  1.00 65.40  ? 492 GLU C CB  1 
ATOM   5068  C CG  . GLU C 1 285 ? -78.872  -5.243  43.892  1.00 72.12  ? 492 GLU C CG  1 
ATOM   5069  C CD  . GLU C 1 285 ? -80.254  -5.361  44.473  1.00 75.53  ? 492 GLU C CD  1 
ATOM   5070  O OE1 . GLU C 1 285 ? -80.726  -4.363  45.051  1.00 70.07  ? 492 GLU C OE1 1 
ATOM   5071  O OE2 . GLU C 1 285 ? -80.859  -6.450  44.350  1.00 83.08  ? 492 GLU C OE2 1 
ATOM   5072  N N   . ALA C 1 286 ? -78.068  -4.133  39.663  1.00 67.00  ? 493 ALA C N   1 
ATOM   5073  C CA  . ALA C 1 286 ? -77.791  -4.503  38.276  1.00 60.03  ? 493 ALA C CA  1 
ATOM   5074  C C   . ALA C 1 286 ? -76.441  -3.995  37.805  1.00 64.85  ? 493 ALA C C   1 
ATOM   5075  O O   . ALA C 1 286 ? -75.784  -4.656  36.998  1.00 69.29  ? 493 ALA C O   1 
ATOM   5076  C CB  . ALA C 1 286 ? -78.870  -3.964  37.353  1.00 54.02  ? 493 ALA C CB  1 
ATOM   5077  N N   . ILE C 1 287 ? -75.998  -2.847  38.302  1.00 64.06  ? 494 ILE C N   1 
ATOM   5078  C CA  . ILE C 1 287 ? -74.862  -2.160  37.700  1.00 62.98  ? 494 ILE C CA  1 
ATOM   5079  C C   . ILE C 1 287 ? -73.615  -2.264  38.566  1.00 61.75  ? 494 ILE C C   1 
ATOM   5080  O O   . ILE C 1 287 ? -72.722  -3.068  38.285  1.00 63.34  ? 494 ILE C O   1 
ATOM   5081  C CB  . ILE C 1 287 ? -75.214  -0.687  37.425  1.00 65.02  ? 494 ILE C CB  1 
ATOM   5082  C CG1 . ILE C 1 287 ? -76.472  -0.611  36.537  1.00 56.72  ? 494 ILE C CG1 1 
ATOM   5083  C CG2 . ILE C 1 287 ? -74.008  0.048   36.827  1.00 58.81  ? 494 ILE C CG2 1 
ATOM   5084  C CD1 . ILE C 1 287 ? -76.931  0.801   36.204  1.00 62.47  ? 494 ILE C CD1 1 
ATOM   5085  N N   . GLU C 1 288 ? -73.538  -1.446  39.617  1.00 68.55  ? 495 GLU C N   1 
ATOM   5086  C CA  . GLU C 1 288 ? -72.316  -1.366  40.416  1.00 65.69  ? 495 GLU C CA  1 
ATOM   5087  C C   . GLU C 1 288 ? -71.926  -2.731  40.992  1.00 65.11  ? 495 GLU C C   1 
ATOM   5088  O O   . GLU C 1 288 ? -70.749  -3.103  40.972  1.00 67.78  ? 495 GLU C O   1 
ATOM   5089  C CB  . GLU C 1 288 ? -72.502  -0.325  41.521  1.00 65.15  ? 495 GLU C CB  1 
ATOM   5090  C CG  . GLU C 1 288 ? -72.153  1.121   41.113  1.00 66.36  ? 495 GLU C CG  1 
ATOM   5091  C CD  . GLU C 1 288 ? -73.289  1.882   40.405  1.00 68.61  ? 495 GLU C CD  1 
ATOM   5092  O OE1 . GLU C 1 288 ? -74.406  1.335   40.231  1.00 71.02  ? 495 GLU C OE1 1 
ATOM   5093  O OE2 . GLU C 1 288 ? -73.049  3.044   40.008  1.00 60.86  ? 495 GLU C OE2 1 
ATOM   5094  N N   . HIS C 1 289 ? -72.903  -3.505  41.481  1.00 67.46  ? 496 HIS C N   1 
ATOM   5095  C CA  . HIS C 1 289 ? -72.654  -4.828  42.056  1.00 66.89  ? 496 HIS C CA  1 
ATOM   5096  C C   . HIS C 1 289 ? -72.217  -5.853  41.028  1.00 65.86  ? 496 HIS C C   1 
ATOM   5097  O O   . HIS C 1 289 ? -71.955  -7.006  41.391  1.00 69.23  ? 496 HIS C O   1 
ATOM   5098  C CB  . HIS C 1 289 ? -73.904  -5.342  42.775  1.00 71.00  ? 496 HIS C CB  1 
ATOM   5099  C CG  . HIS C 1 289 ? -74.194  -4.627  44.059  1.00 76.43  ? 496 HIS C CG  1 
ATOM   5100  N ND1 . HIS C 1 289 ? -73.239  -3.889  44.730  1.00 79.31  ? 496 HIS C ND1 1 
ATOM   5101  C CD2 . HIS C 1 289 ? -75.331  -4.526  44.790  1.00 71.99  ? 496 HIS C CD2 1 
ATOM   5102  C CE1 . HIS C 1 289 ? -73.776  -3.365  45.820  1.00 76.19  ? 496 HIS C CE1 1 
ATOM   5103  N NE2 . HIS C 1 289 ? -75.042  -3.741  45.883  1.00 71.81  ? 496 HIS C NE2 1 
ATOM   5104  N N   . ASN C 1 290 ? -72.135  -5.471  39.758  1.00 67.84  ? 497 ASN C N   1 
ATOM   5105  C CA  . ASN C 1 290 ? -71.702  -6.362  38.694  1.00 64.56  ? 497 ASN C CA  1 
ATOM   5106  C C   . ASN C 1 290 ? -70.367  -5.941  38.104  1.00 63.03  ? 497 ASN C C   1 
ATOM   5107  O O   . ASN C 1 290 ? -69.933  -6.518  37.104  1.00 68.49  ? 497 ASN C O   1 
ATOM   5108  C CB  . ASN C 1 290 ? -72.773  -6.430  37.610  1.00 62.73  ? 497 ASN C CB  1 
ATOM   5109  C CG  . ASN C 1 290 ? -73.880  -7.399  37.962  1.00 65.30  ? 497 ASN C CG  1 
ATOM   5110  O OD1 . ASN C 1 290 ? -73.616  -8.575  38.255  1.00 67.19  ? 497 ASN C OD1 1 
ATOM   5111  N ND2 . ASN C 1 290 ? -75.123  -6.914  37.968  1.00 61.70  ? 497 ASN C ND2 1 
ATOM   5112  N N   . TYR C 1 291 ? -69.692  -4.971  38.723  1.00 62.63  ? 498 TYR C N   1 
ATOM   5113  C CA  . TYR C 1 291 ? -68.435  -4.458  38.191  1.00 60.49  ? 498 TYR C CA  1 
ATOM   5114  C C   . TYR C 1 291 ? -67.303  -5.469  38.274  1.00 55.99  ? 498 TYR C C   1 
ATOM   5115  O O   . TYR C 1 291 ? -66.397  -5.431  37.437  1.00 58.74  ? 498 TYR C O   1 
ATOM   5116  C CB  . TYR C 1 291 ? -68.035  -3.192  38.936  1.00 56.36  ? 498 TYR C CB  1 
ATOM   5117  C CG  . TYR C 1 291 ? -68.783  -1.985  38.476  1.00 57.97  ? 498 TYR C CG  1 
ATOM   5118  C CD1 . TYR C 1 291 ? -69.840  -2.100  37.589  1.00 60.32  ? 498 TYR C CD1 1 
ATOM   5119  C CD2 . TYR C 1 291 ? -68.431  -0.722  38.918  1.00 60.92  ? 498 TYR C CD2 1 
ATOM   5120  C CE1 . TYR C 1 291 ? -70.534  -0.975  37.158  1.00 63.18  ? 498 TYR C CE1 1 
ATOM   5121  C CE2 . TYR C 1 291 ? -69.115  0.402   38.493  1.00 60.20  ? 498 TYR C CE2 1 
ATOM   5122  C CZ  . TYR C 1 291 ? -70.161  0.269   37.620  1.00 59.10  ? 498 TYR C CZ  1 
ATOM   5123  O OH  . TYR C 1 291 ? -70.830  1.391   37.216  1.00 59.36  ? 498 TYR C OH  1 
ATOM   5124  N N   . GLY C 1 292 ? -67.301  -6.332  39.291  1.00 58.55  ? 499 GLY C N   1 
ATOM   5125  C CA  . GLY C 1 292 ? -66.255  -7.338  39.460  1.00 61.61  ? 499 GLY C CA  1 
ATOM   5126  C C   . GLY C 1 292 ? -65.225  -7.153  40.568  1.00 48.82  ? 499 GLY C C   1 
ATOM   5127  O O   . GLY C 1 292 ? -65.168  -6.105  41.202  1.00 51.54  ? 499 GLY C O   1 
ATOM   5128  N N   . CYS C 1 303 ? -66.502  -13.637 42.117  1.00 70.95  ? 510 CYS C N   1 
ATOM   5129  C CA  . CYS C 1 303 ? -66.371  -14.152 40.754  1.00 72.60  ? 510 CYS C CA  1 
ATOM   5130  C C   . CYS C 1 303 ? -67.703  -14.054 39.971  1.00 68.59  ? 510 CYS C C   1 
ATOM   5131  O O   . CYS C 1 303 ? -67.961  -14.850 39.060  1.00 66.29  ? 510 CYS C O   1 
ATOM   5132  C CB  . CYS C 1 303 ? -65.916  -15.616 40.781  1.00 74.43  ? 510 CYS C CB  1 
ATOM   5133  S SG  . CYS C 1 303 ? -67.042  -16.675 41.712  1.00 81.65  ? 510 CYS C SG  1 
ATOM   5134  N N   . THR C 1 304 ? -68.548  -13.095 40.342  1.00 69.79  ? 511 THR C N   1 
ATOM   5135  C CA  . THR C 1 304 ? -69.818  -12.836 39.671  1.00 68.87  ? 511 THR C CA  1 
ATOM   5136  C C   . THR C 1 304 ? -69.750  -11.453 39.037  1.00 70.78  ? 511 THR C C   1 
ATOM   5137  O O   . THR C 1 304 ? -69.461  -10.470 39.733  1.00 71.96  ? 511 THR C O   1 
ATOM   5138  C CB  . THR C 1 304 ? -71.006  -12.893 40.647  1.00 66.65  ? 511 THR C CB  1 
ATOM   5139  O OG1 . THR C 1 304 ? -71.128  -14.201 41.208  1.00 75.80  ? 511 THR C OG1 1 
ATOM   5140  C CG2 . THR C 1 304 ? -72.294  -12.552 39.942  1.00 66.65  ? 511 THR C CG2 1 
ATOM   5141  N N   . ASN C 1 305 ? -70.021  -11.366 37.732  1.00 63.98  ? 512 ASN C N   1 
ATOM   5142  C CA  . ASN C 1 305 ? -69.791  -10.101 37.036  1.00 67.05  ? 512 ASN C CA  1 
ATOM   5143  C C   . ASN C 1 305 ? -70.437  -10.137 35.658  1.00 62.83  ? 512 ASN C C   1 
ATOM   5144  O O   . ASN C 1 305 ? -70.745  -11.206 35.121  1.00 64.27  ? 512 ASN C O   1 
ATOM   5145  C CB  . ASN C 1 305 ? -68.290  -9.816  36.909  1.00 60.10  ? 512 ASN C CB  1 
ATOM   5146  C CG  . ASN C 1 305 ? -67.524  -11.038 36.481  1.00 60.20  ? 512 ASN C CG  1 
ATOM   5147  O OD1 . ASN C 1 305 ? -67.942  -11.748 35.568  1.00 61.04  ? 512 ASN C OD1 1 
ATOM   5148  N ND2 . ASN C 1 305 ? -66.421  -11.318 37.156  1.00 63.32  ? 512 ASN C ND2 1 
ATOM   5149  N N   . ALA C 1 306 ? -70.605  -8.948  35.085  1.00 60.82  ? 513 ALA C N   1 
ATOM   5150  C CA  . ALA C 1 306 ? -71.149  -8.812  33.740  1.00 56.21  ? 513 ALA C CA  1 
ATOM   5151  C C   . ALA C 1 306 ? -70.195  -9.383  32.701  1.00 51.93  ? 513 ALA C C   1 
ATOM   5152  O O   . ALA C 1 306 ? -68.984  -9.187  32.766  1.00 50.33  ? 513 ALA C O   1 
ATOM   5153  C CB  . ALA C 1 306 ? -71.425  -7.342  33.433  1.00 51.04  ? 513 ALA C CB  1 
ATOM   5154  N N   . TYR C 1 307 ? -70.752  -10.095 31.735  1.00 55.91  ? 514 TYR C N   1 
ATOM   5155  C CA  . TYR C 1 307 ? -70.000  -10.636 30.612  1.00 51.06  ? 514 TYR C CA  1 
ATOM   5156  C C   . TYR C 1 307 ? -70.369  -9.986  29.299  1.00 51.43  ? 514 TYR C C   1 
ATOM   5157  O O   . TYR C 1 307 ? -69.517  -9.829  28.425  1.00 51.93  ? 514 TYR C O   1 
ATOM   5158  C CB  . TYR C 1 307 ? -70.259  -12.129 30.489  1.00 51.97  ? 514 TYR C CB  1 
ATOM   5159  C CG  . TYR C 1 307 ? -69.558  -12.822 29.347  1.00 48.25  ? 514 TYR C CG  1 
ATOM   5160  C CD1 . TYR C 1 307 ? -68.273  -12.468 28.954  1.00 48.61  ? 514 TYR C CD1 1 
ATOM   5161  C CD2 . TYR C 1 307 ? -70.168  -13.862 28.691  1.00 45.96  ? 514 TYR C CD2 1 
ATOM   5162  C CE1 . TYR C 1 307 ? -67.632  -13.137 27.934  1.00 46.22  ? 514 TYR C CE1 1 
ATOM   5163  C CE2 . TYR C 1 307 ? -69.534  -14.523 27.665  1.00 50.72  ? 514 TYR C CE2 1 
ATOM   5164  C CZ  . TYR C 1 307 ? -68.269  -14.166 27.293  1.00 44.82  ? 514 TYR C CZ  1 
ATOM   5165  O OH  . TYR C 1 307 ? -67.665  -14.845 26.263  1.00 51.84  ? 514 TYR C OH  1 
ATOM   5166  N N   . MET C 1 308 ? -71.663  -9.698  29.141  1.00 51.57  ? 515 MET C N   1 
ATOM   5167  C CA  . MET C 1 308 ? -72.200  -9.082  27.906  1.00 51.88  ? 515 MET C CA  1 
ATOM   5168  C C   . MET C 1 308 ? -73.142  -7.949  28.301  1.00 55.85  ? 515 MET C C   1 
ATOM   5169  O O   . MET C 1 308 ? -73.928  -8.132  29.229  1.00 61.55  ? 515 MET C O   1 
ATOM   5170  C CB  . MET C 1 308 ? -72.987  -10.109 27.089  1.00 46.27  ? 515 MET C CB  1 
ATOM   5171  C CG  . MET C 1 308 ? -73.328  -9.674  25.686  1.00 50.01  ? 515 MET C CG  1 
ATOM   5172  S SD  . MET C 1 308 ? -74.138  -11.018 24.797  1.00 55.32  ? 515 MET C SD  1 
ATOM   5173  C CE  . MET C 1 308 ? -75.710  -10.258 24.404  1.00 45.96  ? 515 MET C CE  1 
ATOM   5174  N N   . LEU C 1 309 ? -73.018  -6.807  27.633  1.00 52.26  ? 516 LEU C N   1 
ATOM   5175  C CA  . LEU C 1 309 ? -73.851  -5.625  27.953  1.00 49.23  ? 516 LEU C CA  1 
ATOM   5176  C C   . LEU C 1 309 ? -74.721  -5.285  26.747  1.00 51.56  ? 516 LEU C C   1 
ATOM   5177  O O   . LEU C 1 309 ? -74.278  -5.508  25.621  1.00 54.70  ? 516 LEU C O   1 
ATOM   5178  C CB  . LEU C 1 309 ? -72.925  -4.455  28.293  1.00 48.73  ? 516 LEU C CB  1 
ATOM   5179  C CG  . LEU C 1 309 ? -72.022  -4.629  29.508  1.00 47.10  ? 516 LEU C CG  1 
ATOM   5180  C CD1 . LEU C 1 309 ? -71.072  -3.453  29.624  1.00 46.71  ? 516 LEU C CD1 1 
ATOM   5181  C CD2 . LEU C 1 309 ? -72.851  -4.756  30.768  1.00 44.58  ? 516 LEU C CD2 1 
ATOM   5182  N N   . VAL C 1 310 ? -75.922  -4.775  26.990  1.00 48.85  ? 517 VAL C N   1 
ATOM   5183  C CA  . VAL C 1 310 ? -76.831  -4.354  25.891  1.00 52.33  ? 517 VAL C CA  1 
ATOM   5184  C C   . VAL C 1 310 ? -77.139  -2.879  26.121  1.00 49.48  ? 517 VAL C C   1 
ATOM   5185  O O   . VAL C 1 310 ? -77.700  -2.560  27.159  1.00 55.31  ? 517 VAL C O   1 
ATOM   5186  C CB  . VAL C 1 310 ? -78.112  -5.200  25.814  1.00 52.65  ? 517 VAL C CB  1 
ATOM   5187  C CG1 . VAL C 1 310 ? -79.076  -4.675  24.763  1.00 47.44  ? 517 VAL C CG1 1 
ATOM   5188  C CG2 . VAL C 1 310 ? -77.797  -6.661  25.558  1.00 50.97  ? 517 VAL C CG2 1 
ATOM   5189  N N   . TYR C 1 311 ? -76.697  -2.018  25.218  1.00 48.44  ? 518 TYR C N   1 
ATOM   5190  C CA  . TYR C 1 311 ? -77.010  -0.572  25.294  1.00 49.38  ? 518 TYR C CA  1 
ATOM   5191  C C   . TYR C 1 311 ? -77.920  -0.234  24.115  1.00 44.65  ? 518 TYR C C   1 
ATOM   5192  O O   . TYR C 1 311 ? -77.761  -0.822  23.052  1.00 46.18  ? 518 TYR C O   1 
ATOM   5193  C CB  . TYR C 1 311 ? -75.740  0.272   25.254  1.00 42.90  ? 518 TYR C CB  1 
ATOM   5194  C CG  . TYR C 1 311 ? -74.973  0.391   26.543  1.00 43.08  ? 518 TYR C CG  1 
ATOM   5195  C CD1 . TYR C 1 311 ? -74.033  -0.557  26.896  1.00 48.86  ? 518 TYR C CD1 1 
ATOM   5196  C CD2 . TYR C 1 311 ? -75.150  1.472   27.386  1.00 47.37  ? 518 TYR C CD2 1 
ATOM   5197  C CE1 . TYR C 1 311 ? -73.308  -0.447  28.067  1.00 50.86  ? 518 TYR C CE1 1 
ATOM   5198  C CE2 . TYR C 1 311 ? -74.440  1.593   28.568  1.00 45.58  ? 518 TYR C CE2 1 
ATOM   5199  C CZ  . TYR C 1 311 ? -73.510  0.630   28.906  1.00 47.01  ? 518 TYR C CZ  1 
ATOM   5200  O OH  . TYR C 1 311 ? -72.789  0.722   30.056  1.00 50.51  ? 518 TYR C OH  1 
ATOM   5201  N N   . ILE C 1 312 ? -78.873  0.667   24.313  1.00 40.82  ? 519 ILE C N   1 
ATOM   5202  C CA  . ILE C 1 312 ? -79.809  1.059   23.265  1.00 48.31  ? 519 ILE C CA  1 
ATOM   5203  C C   . ILE C 1 312 ? -79.651  2.554   23.022  1.00 48.65  ? 519 ILE C C   1 
ATOM   5204  O O   . ILE C 1 312 ? -79.534  3.343   23.966  1.00 53.60  ? 519 ILE C O   1 
ATOM   5205  C CB  . ILE C 1 312 ? -81.269  0.682   23.615  1.00 52.35  ? 519 ILE C CB  1 
ATOM   5206  C CG1 . ILE C 1 312 ? -81.373  -0.833  23.842  1.00 52.14  ? 519 ILE C CG1 1 
ATOM   5207  C CG2 . ILE C 1 312 ? -82.250  1.124   22.515  1.00 48.09  ? 519 ILE C CG2 1 
ATOM   5208  C CD1 . ILE C 1 312 ? -82.732  -1.310  24.229  1.00 47.93  ? 519 ILE C CD1 1 
ATOM   5209  N N   . ARG C 1 313 ? -79.607  2.936   21.756  1.00 41.93  ? 520 ARG C N   1 
ATOM   5210  C CA  . ARG C 1 313 ? -79.297  4.310   21.413  1.00 47.31  ? 520 ARG C CA  1 
ATOM   5211  C C   . ARG C 1 313 ? -80.441  5.212   21.835  1.00 50.96  ? 520 ARG C C   1 
ATOM   5212  O O   . ARG C 1 313 ? -81.606  4.928   21.542  1.00 53.51  ? 520 ARG C O   1 
ATOM   5213  C CB  . ARG C 1 313 ? -79.037  4.435   19.913  1.00 51.01  ? 520 ARG C CB  1 
ATOM   5214  C CG  . ARG C 1 313 ? -78.354  5.698   19.526  1.00 46.54  ? 520 ARG C CG  1 
ATOM   5215  C CD  . ARG C 1 313 ? -78.136  5.744   18.072  1.00 48.03  ? 520 ARG C CD  1 
ATOM   5216  N NE  . ARG C 1 313 ? -77.359  6.924   17.727  1.00 54.87  ? 520 ARG C NE  1 
ATOM   5217  C CZ  . ARG C 1 313 ? -76.172  6.894   17.138  1.00 51.50  ? 520 ARG C CZ  1 
ATOM   5218  N NH1 . ARG C 1 313 ? -75.616  5.733   16.824  1.00 42.26  ? 520 ARG C NH1 1 
ATOM   5219  N NH2 . ARG C 1 313 ? -75.544  8.028   16.863  1.00 52.40  ? 520 ARG C NH2 1 
ATOM   5220  N N   . GLU C 1 314 ? -80.095  6.304   22.520  1.00 50.45  ? 521 GLU C N   1 
ATOM   5221  C CA  . GLU C 1 314 ? -81.085  7.209   23.089  1.00 52.36  ? 521 GLU C CA  1 
ATOM   5222  C C   . GLU C 1 314 ? -82.146  7.608   22.069  1.00 59.07  ? 521 GLU C C   1 
ATOM   5223  O O   . GLU C 1 314 ? -83.322  7.745   22.418  1.00 62.33  ? 521 GLU C O   1 
ATOM   5224  C CB  . GLU C 1 314 ? -80.359  8.437   23.641  1.00 58.61  ? 521 GLU C CB  1 
ATOM   5225  C CG  . GLU C 1 314 ? -81.037  9.239   24.745  1.00 60.65  ? 521 GLU C CG  1 
ATOM   5226  C CD  . GLU C 1 314 ? -80.207  10.485  25.118  1.00 74.55  ? 521 GLU C CD  1 
ATOM   5227  O OE1 . GLU C 1 314 ? -79.655  10.559  26.245  1.00 77.72  ? 521 GLU C OE1 1 
ATOM   5228  O OE2 . GLU C 1 314 ? -80.071  11.380  24.253  1.00 74.76  ? 521 GLU C OE2 1 
ATOM   5229  N N   . SER C 1 315 ? -81.767  7.765   20.802  1.00 56.21  ? 522 SER C N   1 
ATOM   5230  C CA  . SER C 1 315 ? -82.697  8.247   19.794  1.00 44.31  ? 522 SER C CA  1 
ATOM   5231  C C   . SER C 1 315 ? -83.588  7.157   19.221  1.00 50.99  ? 522 SER C C   1 
ATOM   5232  O O   . SER C 1 315 ? -84.557  7.473   18.528  1.00 55.86  ? 522 SER C O   1 
ATOM   5233  C CB  . SER C 1 315 ? -81.928  8.933   18.659  1.00 53.58  ? 522 SER C CB  1 
ATOM   5234  O OG  . SER C 1 315 ? -81.303  7.990   17.798  1.00 61.29  ? 522 SER C OG  1 
ATOM   5235  N N   . LYS C 1 316 ? -83.293  5.894   19.506  1.00 53.43  ? 523 LYS C N   1 
ATOM   5236  C CA  . LYS C 1 316 ? -84.077  4.779   18.919  1.00 55.93  ? 523 LYS C CA  1 
ATOM   5237  C C   . LYS C 1 316 ? -84.821  4.022   20.021  1.00 58.05  ? 523 LYS C C   1 
ATOM   5238  O O   . LYS C 1 316 ? -85.531  3.076   19.685  1.00 60.46  ? 523 LYS C O   1 
ATOM   5239  C CB  . LYS C 1 316 ? -83.150  3.857   18.123  1.00 57.71  ? 523 LYS C CB  1 
ATOM   5240  C CG  . LYS C 1 316 ? -82.305  4.531   17.054  1.00 51.96  ? 523 LYS C CG  1 
ATOM   5241  C CD  . LYS C 1 316 ? -82.965  4.524   15.699  1.00 72.84  ? 523 LYS C CD  1 
ATOM   5242  C CE  . LYS C 1 316 ? -82.874  5.858   14.995  1.00 52.79  ? 523 LYS C CE  1 
ATOM   5243  N NZ  . LYS C 1 316 ? -84.202  6.502   14.877  1.00 67.49  ? 523 LYS C NZ  1 
ATOM   5244  N N   . LEU C 1 317 ? -84.687  4.446   21.276  1.00 56.31  ? 524 LEU C N   1 
ATOM   5245  C CA  . LEU C 1 317 ? -85.320  3.741   22.419  1.00 57.98  ? 524 LEU C CA  1 
ATOM   5246  C C   . LEU C 1 317 ? -86.824  3.626   22.196  1.00 60.45  ? 524 LEU C C   1 
ATOM   5247  O O   . LEU C 1 317 ? -87.354  2.541   22.388  1.00 66.44  ? 524 LEU C O   1 
ATOM   5248  C CB  . LEU C 1 317 ? -85.025  4.520   23.701  1.00 56.06  ? 524 LEU C CB  1 
ATOM   5249  C CG  . LEU C 1 317 ? -85.005  3.692   24.981  1.00 56.43  ? 524 LEU C CG  1 
ATOM   5250  C CD1 . LEU C 1 317 ? -83.589  3.552   25.502  1.00 60.29  ? 524 LEU C CD1 1 
ATOM   5251  C CD2 . LEU C 1 317 ? -85.900  4.314   26.037  1.00 73.72  ? 524 LEU C CD2 1 
ATOM   5252  N N   . SER C 1 318 ? -87.476  4.714   21.808  1.00 59.78  ? 525 SER C N   1 
ATOM   5253  C CA  . SER C 1 318 ? -88.942  4.704   21.584  1.00 62.53  ? 525 SER C CA  1 
ATOM   5254  C C   . SER C 1 318 ? -89.321  3.649   20.550  1.00 58.38  ? 525 SER C C   1 
ATOM   5255  O O   . SER C 1 318 ? -90.352  3.011   20.739  1.00 62.92  ? 525 SER C O   1 
ATOM   5256  C CB  . SER C 1 318 ? -89.420  6.058   21.152  1.00 68.89  ? 525 SER C CB  1 
ATOM   5257  O OG  . SER C 1 318 ? -88.827  6.442   19.920  1.00 67.25  ? 525 SER C OG  1 
ATOM   5258  N N   . GLU C 1 319 ? -88.522  3.489   19.499  1.00 56.40  ? 526 GLU C N   1 
ATOM   5259  C CA  . GLU C 1 319 ? -88.877  2.554   18.407  1.00 53.86  ? 526 GLU C CA  1 
ATOM   5260  C C   . GLU C 1 319 ? -88.535  1.128   18.819  1.00 59.27  ? 526 GLU C C   1 
ATOM   5261  O O   . GLU C 1 319 ? -89.396  0.255   18.678  1.00 63.84  ? 526 GLU C O   1 
ATOM   5262  C CB  . GLU C 1 319 ? -88.148  2.958   17.131  1.00 55.27  ? 526 GLU C CB  1 
ATOM   5263  C CG  . GLU C 1 319 ? -88.902  2.602   15.868  1.00 62.97  ? 526 GLU C CG  1 
ATOM   5264  C CD  . GLU C 1 319 ? -88.018  2.471   14.644  1.00 68.23  ? 526 GLU C CD  1 
ATOM   5265  O OE1 . GLU C 1 319 ? -88.354  1.662   13.764  1.00 68.14  ? 526 GLU C OE1 1 
ATOM   5266  O OE2 . GLU C 1 319 ? -86.994  3.176   14.577  1.00 68.56  ? 526 GLU C OE2 1 
ATOM   5267  N N   . VAL C 1 320 ? -87.319  0.910   19.301  1.00 59.66  ? 527 VAL C N   1 
ATOM   5268  C CA  . VAL C 1 320 ? -86.884  -0.467  19.659  1.00 63.56  ? 527 VAL C CA  1 
ATOM   5269  C C   . VAL C 1 320 ? -87.780  -0.973  20.781  1.00 64.43  ? 527 VAL C C   1 
ATOM   5270  O O   . VAL C 1 320 ? -88.204  -2.119  20.700  1.00 62.98  ? 527 VAL C O   1 
ATOM   5271  C CB  . VAL C 1 320 ? -85.399  -0.501  20.056  1.00 63.41  ? 527 VAL C CB  1 
ATOM   5272  C CG1 . VAL C 1 320 ? -84.967  -1.876  20.535  1.00 57.23  ? 527 VAL C CG1 1 
ATOM   5273  C CG2 . VAL C 1 320 ? -84.500  -0.025  18.929  1.00 61.32  ? 527 VAL C CG2 1 
ATOM   5274  N N   . LEU C 1 321 ? -88.080  -0.131  21.763  1.00 64.32  ? 528 LEU C N   1 
ATOM   5275  C CA  . LEU C 1 321 ? -88.837  -0.575  22.921  1.00 61.14  ? 528 LEU C CA  1 
ATOM   5276  C C   . LEU C 1 321 ? -90.316  -0.234  22.811  1.00 62.58  ? 528 LEU C C   1 
ATOM   5277  O O   . LEU C 1 321 ? -91.025  -0.229  23.825  1.00 61.18  ? 528 LEU C O   1 
ATOM   5278  C CB  . LEU C 1 321 ? -88.230  0.016   24.188  1.00 57.43  ? 528 LEU C CB  1 
ATOM   5279  C CG  . LEU C 1 321 ? -86.811  -0.511  24.406  1.00 59.04  ? 528 LEU C CG  1 
ATOM   5280  C CD1 . LEU C 1 321 ? -86.174  0.068   25.657  1.00 53.14  ? 528 LEU C CD1 1 
ATOM   5281  C CD2 . LEU C 1 321 ? -86.823  -2.030  24.462  1.00 53.26  ? 528 LEU C CD2 1 
ATOM   5282  N N   . GLN C 1 322 ? -90.786  0.047   21.595  1.00 61.90  ? 529 GLN C N   1 
ATOM   5283  C CA  . GLN C 1 322 ? -92.205  0.279   21.364  1.00 68.35  ? 529 GLN C CA  1 
ATOM   5284  C C   . GLN C 1 322 ? -93.030  -0.914  21.834  1.00 72.95  ? 529 GLN C C   1 
ATOM   5285  O O   . GLN C 1 322 ? -92.663  -2.073  21.607  1.00 69.17  ? 529 GLN C O   1 
ATOM   5286  C CB  . GLN C 1 322 ? -92.463  0.540   19.880  1.00 69.01  ? 529 GLN C CB  1 
ATOM   5287  N N   . ALA C 1 323 ? -94.156  -0.616  22.484  1.00 67.26  ? 530 ALA C N   1 
ATOM   5288  C CA  . ALA C 1 323 ? -94.979  -1.645  23.106  1.00 69.05  ? 530 ALA C CA  1 
ATOM   5289  C C   . ALA C 1 323 ? -95.518  -2.636  22.078  1.00 71.18  ? 530 ALA C C   1 
ATOM   5290  O O   . ALA C 1 323 ? -95.847  -2.280  20.939  1.00 63.04  ? 530 ALA C O   1 
ATOM   5291  C CB  . ALA C 1 323 ? -96.141  -1.007  23.864  1.00 61.81  ? 530 ALA C CB  1 
ATOM   5292  N N   . VAL C 1 324 ? -95.620  -3.894  22.515  1.00 74.56  ? 531 VAL C N   1 
ATOM   5293  C CA  . VAL C 1 324 ? -96.060  -5.021  21.695  1.00 74.31  ? 531 VAL C CA  1 
ATOM   5294  C C   . VAL C 1 324 ? -97.415  -5.478  22.219  1.00 73.46  ? 531 VAL C C   1 
ATOM   5295  O O   . VAL C 1 324 ? -97.513  -6.013  23.330  1.00 70.31  ? 531 VAL C O   1 
ATOM   5296  C CB  . VAL C 1 324 ? -95.047  -6.175  21.728  1.00 75.33  ? 531 VAL C CB  1 
ATOM   5297  C CG1 . VAL C 1 324 ? -95.498  -7.315  20.813  1.00 78.58  ? 531 VAL C CG1 1 
ATOM   5298  C CG2 . VAL C 1 324 ? -93.669  -5.688  21.340  1.00 68.76  ? 531 VAL C CG2 1 
ATOM   5299  N N   . THR C 1 325 ? -98.444  -5.272  21.406  1.00 82.92  ? 532 THR C N   1 
ATOM   5300  C CA  . THR C 1 325 ? -99.826  -5.611  21.813  1.00 87.79  ? 532 THR C CA  1 
ATOM   5301  C C   . THR C 1 325 ? -100.212 -7.002  21.327  1.00 86.54  ? 532 THR C C   1 
ATOM   5302  O O   . THR C 1 325 ? -99.489  -7.577  20.512  1.00 83.11  ? 532 THR C O   1 
ATOM   5303  C CB  . THR C 1 325 ? -100.818 -4.600  21.231  1.00 82.57  ? 532 THR C CB  1 
ATOM   5304  O OG1 . THR C 1 325 ? -100.769 -4.685  19.807  1.00 84.28  ? 532 THR C OG1 1 
ATOM   5305  C CG2 . THR C 1 325 ? -100.525 -3.180  21.660  1.00 82.70  ? 532 THR C CG2 1 
ATOM   5306  N N   . ASP C 1 326 ? -101.326 -7.536  21.830  1.00 92.12  ? 533 ASP C N   1 
ATOM   5307  C CA  . ASP C 1 326 ? -101.824 -8.846  21.333  1.00 92.00  ? 533 ASP C CA  1 
ATOM   5308  C C   . ASP C 1 326 ? -102.261 -8.649  19.885  1.00 86.70  ? 533 ASP C C   1 
ATOM   5309  O O   . ASP C 1 326 ? -102.320 -9.643  19.150  1.00 84.80  ? 533 ASP C O   1 
ATOM   5310  C CB  . ASP C 1 326 ? -102.936 -9.416  22.216  1.00 87.94  ? 533 ASP C CB  1 
ATOM   5311  C CG  . ASP C 1 326 ? -102.884 -10.923 22.393  1.00 95.13  ? 533 ASP C CG  1 
ATOM   5312  O OD1 . ASP C 1 326 ? -102.765 -11.634 21.381  1.00 95.16  ? 533 ASP C OD1 1 
ATOM   5313  O OD2 . ASP C 1 326 ? -102.985 -11.375 23.545  1.00 93.63  ? 533 ASP C OD2 1 
ATOM   5314  N N   . HIS C 1 327 ? -102.569 -7.411  19.500  1.00 85.55  ? 534 HIS C N   1 
ATOM   5315  C CA  . HIS C 1 327 ? -102.872 -7.162  18.098  1.00 84.35  ? 534 HIS C CA  1 
ATOM   5316  C C   . HIS C 1 327 ? -101.654 -7.367  17.206  1.00 87.53  ? 534 HIS C C   1 
ATOM   5317  O O   . HIS C 1 327 ? -101.801 -7.646  16.012  1.00 86.25  ? 534 HIS C O   1 
ATOM   5318  C CB  . HIS C 1 327 ? -103.416 -5.746  17.918  1.00 78.86  ? 534 HIS C CB  1 
ATOM   5319  C CG  . HIS C 1 327 ? -104.192 -5.580  16.656  1.00 92.32  ? 534 HIS C CG  1 
ATOM   5320  N ND1 . HIS C 1 327 ? -105.554 -5.781  16.595  1.00 98.17  ? 534 HIS C ND1 1 
ATOM   5321  C CD2 . HIS C 1 327 ? -103.795 -5.285  15.394  1.00 95.39  ? 534 HIS C CD2 1 
ATOM   5322  C CE1 . HIS C 1 327 ? -105.965 -5.603  15.352  1.00 95.40  ? 534 HIS C CE1 1 
ATOM   5323  N NE2 . HIS C 1 327 ? -104.920 -5.296  14.605  1.00 95.04  ? 534 HIS C NE2 1 
ATOM   5324  N N   . ASP C 1 328 ? -100.451 -7.237  17.761  1.00 86.97  ? 535 ASP C N   1 
ATOM   5325  C CA  . ASP C 1 328 ? -99.226  -7.339  16.977  1.00 82.05  ? 535 ASP C CA  1 
ATOM   5326  C C   . ASP C 1 328 ? -99.016  -8.761  16.462  1.00 85.36  ? 535 ASP C C   1 
ATOM   5327  O O   . ASP C 1 328 ? -98.071  -9.011  15.707  1.00 88.82  ? 535 ASP C O   1 
ATOM   5328  C CB  . ASP C 1 328 ? -97.998  -6.905  17.805  1.00 86.78  ? 535 ASP C CB  1 
ATOM   5329  C CG  . ASP C 1 328 ? -97.778  -5.387  17.814  1.00 86.50  ? 535 ASP C CG  1 
ATOM   5330  O OD1 . ASP C 1 328 ? -97.364  -4.845  16.769  1.00 84.35  ? 535 ASP C OD1 1 
ATOM   5331  O OD2 . ASP C 1 328 ? -98.005  -4.739  18.867  1.00 79.50  ? 535 ASP C OD2 1 
ATOM   5332  N N   . ILE C 1 329 ? -99.878  -9.701  16.846  1.00 82.15  ? 536 ILE C N   1 
ATOM   5333  C CA  . ILE C 1 329 ? -99.544  -11.106 16.650  1.00 85.35  ? 536 ILE C CA  1 
ATOM   5334  C C   . ILE C 1 329 ? -100.349 -11.801 15.548  1.00 79.71  ? 536 ILE C C   1 
ATOM   5335  O O   . ILE C 1 329 ? -101.574 -11.780 15.542  1.00 82.79  ? 536 ILE C O   1 
ATOM   5336  C CB  . ILE C 1 329 ? -99.670  -11.848 17.997  1.00 87.39  ? 536 ILE C CB  1 
ATOM   5337  C CG1 . ILE C 1 329 ? -98.999  -11.014 19.103  1.00 85.13  ? 536 ILE C CG1 1 
ATOM   5338  C CG2 . ILE C 1 329 ? -99.029  -13.215 17.899  1.00 82.56  ? 536 ILE C CG2 1 
ATOM   5339  C CD1 . ILE C 1 329 ? -99.362  -11.395 20.523  1.00 82.79  ? 536 ILE C CD1 1 
ATOM   5340  N N   . MET D 2 1   ? -52.943  -15.253 0.995   1.00 48.24  ? 1   MET D N   1 
ATOM   5341  C CA  . MET D 2 1   ? -53.295  -13.911 1.427   1.00 46.23  ? 1   MET D CA  1 
ATOM   5342  C C   . MET D 2 1   ? -53.059  -13.739 2.933   1.00 54.24  ? 1   MET D C   1 
ATOM   5343  O O   . MET D 2 1   ? -53.228  -14.694 3.706   1.00 54.80  ? 1   MET D O   1 
ATOM   5344  C CB  . MET D 2 1   ? -54.756  -13.629 1.095   1.00 44.68  ? 1   MET D CB  1 
ATOM   5345  C CG  . MET D 2 1   ? -55.728  -14.441 1.922   1.00 44.46  ? 1   MET D CG  1 
ATOM   5346  S SD  . MET D 2 1   ? -57.332  -14.488 1.150   1.00 49.83  ? 1   MET D SD  1 
ATOM   5347  C CE  . MET D 2 1   ? -58.265  -15.568 2.236   1.00 44.97  ? 1   MET D CE  1 
ATOM   5348  N N   . GLN D 2 2   ? -52.698  -12.529 3.354   1.00 46.82  ? 2   GLN D N   1 
ATOM   5349  C CA  . GLN D 2 2   ? -52.457  -12.245 4.764   1.00 47.07  ? 2   GLN D CA  1 
ATOM   5350  C C   . GLN D 2 2   ? -53.687  -11.569 5.359   1.00 51.22  ? 2   GLN D C   1 
ATOM   5351  O O   . GLN D 2 2   ? -54.001  -10.424 5.002   1.00 52.61  ? 2   GLN D O   1 
ATOM   5352  C CB  . GLN D 2 2   ? -51.233  -11.355 4.946   1.00 47.47  ? 2   GLN D CB  1 
ATOM   5353  C CG  . GLN D 2 2   ? -51.091  -10.785 6.343   1.00 43.58  ? 2   GLN D CG  1 
ATOM   5354  C CD  . GLN D 2 2   ? -50.072  -9.661  6.404   1.00 53.11  ? 2   GLN D CD  1 
ATOM   5355  O OE1 . GLN D 2 2   ? -50.348  -8.536  5.978   1.00 56.30  ? 2   GLN D OE1 1 
ATOM   5356  N NE2 . GLN D 2 2   ? -48.876  -9.964  6.925   1.00 56.16  ? 2   GLN D NE2 1 
ATOM   5357  N N   . ILE D 2 3   ? -54.366  -12.271 6.280   1.00 47.40  ? 3   ILE D N   1 
ATOM   5358  C CA  . ILE D 2 3   ? -55.480  -11.719 7.049   1.00 46.61  ? 3   ILE D CA  1 
ATOM   5359  C C   . ILE D 2 3   ? -55.006  -11.278 8.424   1.00 45.75  ? 3   ILE D C   1 
ATOM   5360  O O   . ILE D 2 3   ? -53.830  -11.404 8.775   1.00 42.52  ? 3   ILE D O   1 
ATOM   5361  C CB  . ILE D 2 3   ? -56.661  -12.715 7.189   1.00 42.35  ? 3   ILE D CB  1 
ATOM   5362  C CG1 . ILE D 2 3   ? -56.415  -13.757 8.288   1.00 43.80  ? 3   ILE D CG1 1 
ATOM   5363  C CG2 . ILE D 2 3   ? -56.930  -13.413 5.892   1.00 43.75  ? 3   ILE D CG2 1 
ATOM   5364  C CD1 . ILE D 2 3   ? -57.555  -14.736 8.460   1.00 38.85  ? 3   ILE D CD1 1 
ATOM   5365  N N   . PHE D 2 4   ? -55.928  -10.737 9.205   1.00 48.78  ? 4   PHE D N   1 
ATOM   5366  C CA  . PHE D 2 4   ? -55.656  -10.320 10.567  1.00 46.38  ? 4   PHE D CA  1 
ATOM   5367  C C   . PHE D 2 4   ? -56.542  -11.101 11.506  1.00 46.40  ? 4   PHE D C   1 
ATOM   5368  O O   . PHE D 2 4   ? -57.723  -11.324 11.224  1.00 47.21  ? 4   PHE D O   1 
ATOM   5369  C CB  . PHE D 2 4   ? -55.931  -8.843  10.760  1.00 48.25  ? 4   PHE D CB  1 
ATOM   5370  C CG  . PHE D 2 4   ? -55.187  -7.966  9.821   1.00 52.10  ? 4   PHE D CG  1 
ATOM   5371  C CD1 . PHE D 2 4   ? -53.799  -7.873  9.890   1.00 51.73  ? 4   PHE D CD1 1 
ATOM   5372  C CD2 . PHE D 2 4   ? -55.861  -7.228  8.872   1.00 49.86  ? 4   PHE D CD2 1 
ATOM   5373  C CE1 . PHE D 2 4   ? -53.101  -7.059  9.028   1.00 47.62  ? 4   PHE D CE1 1 
ATOM   5374  C CE2 . PHE D 2 4   ? -55.172  -6.410  8.002   1.00 54.43  ? 4   PHE D CE2 1 
ATOM   5375  C CZ  . PHE D 2 4   ? -53.783  -6.329  8.085   1.00 55.29  ? 4   PHE D CZ  1 
ATOM   5376  N N   . VAL D 2 5   ? -55.978  -11.430 12.664  1.00 49.21  ? 5   VAL D N   1 
ATOM   5377  C CA  . VAL D 2 5   ? -56.768  -12.072 13.744  1.00 46.58  ? 5   VAL D CA  1 
ATOM   5378  C C   . VAL D 2 5   ? -56.532  -11.211 14.983  1.00 47.43  ? 5   VAL D C   1 
ATOM   5379  O O   . VAL D 2 5   ? -55.383  -11.112 15.414  1.00 52.80  ? 5   VAL D O   1 
ATOM   5380  C CB  . VAL D 2 5   ? -56.370  -13.539 13.976  1.00 47.83  ? 5   VAL D CB  1 
ATOM   5381  C CG1 . VAL D 2 5   ? -57.094  -14.128 15.174  1.00 49.30  ? 5   VAL D CG1 1 
ATOM   5382  C CG2 . VAL D 2 5   ? -56.594  -14.397 12.744  1.00 39.00  ? 5   VAL D CG2 1 
ATOM   5383  N N   . LYS D 2 6   ? -57.574  -10.565 15.496  1.00 50.64  ? 6   LYS D N   1 
ATOM   5384  C CA  . LYS D 2 6   ? -57.469  -9.764  16.713  1.00 49.68  ? 6   LYS D CA  1 
ATOM   5385  C C   . LYS D 2 6   ? -57.576  -10.707 17.911  1.00 45.70  ? 6   LYS D C   1 
ATOM   5386  O O   . LYS D 2 6   ? -58.620  -11.340 18.119  1.00 49.46  ? 6   LYS D O   1 
ATOM   5387  C CB  . LYS D 2 6   ? -58.545  -8.676  16.753  1.00 48.02  ? 6   LYS D CB  1 
ATOM   5388  C CG  . LYS D 2 6   ? -58.099  -7.369  17.442  1.00 52.25  ? 6   LYS D CG  1 
ATOM   5389  C CD  . LYS D 2 6   ? -59.243  -6.410  17.726  1.00 51.94  ? 6   LYS D CD  1 
ATOM   5390  N N   . THR D 2 7   ? -56.484  -10.822 18.660  1.00 45.63  ? 7   THR D N   1 
ATOM   5391  C CA  . THR D 2 7   ? -56.399  -11.844 19.733  1.00 54.83  ? 7   THR D CA  1 
ATOM   5392  C C   . THR D 2 7   ? -57.043  -11.424 21.052  1.00 57.48  ? 7   THR D C   1 
ATOM   5393  O O   . THR D 2 7   ? -57.579  -10.313 21.132  1.00 56.00  ? 7   THR D O   1 
ATOM   5394  C CB  . THR D 2 7   ? -54.931  -12.249 19.928  1.00 61.96  ? 7   THR D CB  1 
ATOM   5395  O OG1 . THR D 2 7   ? -54.864  -13.405 20.764  1.00 74.14  ? 7   THR D OG1 1 
ATOM   5396  C CG2 . THR D 2 7   ? -54.071  -11.154 20.516  1.00 55.70  ? 7   THR D CG2 1 
ATOM   5397  N N   . LEU D 2 8   ? -56.990  -12.315 22.040  1.00 58.77  ? 8   LEU D N   1 
ATOM   5398  C CA  . LEU D 2 8   ? -57.637  -12.061 23.347  1.00 57.85  ? 8   LEU D CA  1 
ATOM   5399  C C   . LEU D 2 8   ? -56.943  -10.894 24.040  1.00 62.81  ? 8   LEU D C   1 
ATOM   5400  O O   . LEU D 2 8   ? -57.632  -10.154 24.750  1.00 66.31  ? 8   LEU D O   1 
ATOM   5401  C CB  . LEU D 2 8   ? -57.544  -13.342 24.175  1.00 53.59  ? 8   LEU D CB  1 
ATOM   5402  C CG  . LEU D 2 8   ? -57.879  -14.622 23.418  1.00 61.67  ? 8   LEU D CG  1 
ATOM   5403  C CD1 . LEU D 2 8   ? -57.330  -15.836 24.143  1.00 54.92  ? 8   LEU D CD1 1 
ATOM   5404  C CD2 . LEU D 2 8   ? -59.377  -14.751 23.211  1.00 59.89  ? 8   LEU D CD2 1 
ATOM   5405  N N   . THR D 2 9   ? -55.640  -10.738 23.822  1.00 61.47  ? 9   THR D N   1 
ATOM   5406  C CA  . THR D 2 9   ? -54.885  -9.615  24.429  1.00 57.68  ? 9   THR D CA  1 
ATOM   5407  C C   . THR D 2 9   ? -55.352  -8.298  23.809  1.00 63.28  ? 9   THR D C   1 
ATOM   5408  O O   . THR D 2 9   ? -55.066  -7.249  24.399  1.00 65.73  ? 9   THR D O   1 
ATOM   5409  C CB  . THR D 2 9   ? -53.376  -9.823  24.262  1.00 67.76  ? 9   THR D CB  1 
ATOM   5410  O OG1 . THR D 2 9   ? -52.940  -9.232  23.038  1.00 73.27  ? 9   THR D OG1 1 
ATOM   5411  C CG2 . THR D 2 9   ? -52.975  -11.282 24.282  1.00 65.31  ? 9   THR D CG2 1 
ATOM   5412  N N   . GLY D 2 10  ? -56.036  -8.358  22.666  1.00 65.77  ? 10  GLY D N   1 
ATOM   5413  C CA  . GLY D 2 10  ? -56.532  -7.148  21.985  1.00 63.51  ? 10  GLY D CA  1 
ATOM   5414  C C   . GLY D 2 10  ? -55.649  -6.791  20.812  1.00 61.27  ? 10  GLY D C   1 
ATOM   5415  O O   . GLY D 2 10  ? -56.086  -6.015  19.954  1.00 58.30  ? 10  GLY D O   1 
ATOM   5416  N N   . LYS D 2 11  ? -54.446  -7.349  20.787  1.00 56.53  ? 11  LYS D N   1 
ATOM   5417  C CA  . LYS D 2 11  ? -53.495  -7.059  19.700  1.00 56.38  ? 11  LYS D CA  1 
ATOM   5418  C C   . LYS D 2 11  ? -53.940  -7.756  18.421  1.00 60.21  ? 11  LYS D C   1 
ATOM   5419  O O   . LYS D 2 11  ? -54.717  -8.707  18.482  1.00 57.25  ? 11  LYS D O   1 
ATOM   5420  C CB  . LYS D 2 11  ? -52.093  -7.535  20.080  1.00 52.38  ? 11  LYS D CB  1 
ATOM   5421  N N   . THR D 2 12  ? -53.445  -7.274  17.296  1.00 55.67  ? 12  THR D N   1 
ATOM   5422  C CA  . THR D 2 12  ? -53.779  -7.878  16.024  1.00 52.80  ? 12  THR D CA  1 
ATOM   5423  C C   . THR D 2 12  ? -52.546  -8.594  15.528  1.00 52.22  ? 12  THR D C   1 
ATOM   5424  O O   . THR D 2 12  ? -51.484  -7.981  15.406  1.00 58.27  ? 12  THR D O   1 
ATOM   5425  C CB  . THR D 2 12  ? -54.211  -6.827  15.011  1.00 59.59  ? 12  THR D CB  1 
ATOM   5426  O OG1 . THR D 2 12  ? -54.987  -5.825  15.677  1.00 70.03  ? 12  THR D OG1 1 
ATOM   5427  C CG2 . THR D 2 12  ? -55.026  -7.466  13.893  1.00 54.48  ? 12  THR D CG2 1 
ATOM   5428  N N   . ILE D 2 13  ? -52.672  -9.875  15.268  1.00 44.18  ? 13  ILE D N   1 
ATOM   5429  C CA  . ILE D 2 13  ? -51.605  -10.576 14.621  1.00 47.85  ? 13  ILE D CA  1 
ATOM   5430  C C   . ILE D 2 13  ? -51.986  -10.752 13.161  1.00 48.71  ? 13  ILE D C   1 
ATOM   5431  O O   . ILE D 2 13  ? -53.157  -10.667 12.774  1.00 49.60  ? 13  ILE D O   1 
ATOM   5432  C CB  . ILE D 2 13  ? -51.268  -11.928 15.306  1.00 49.15  ? 13  ILE D CB  1 
ATOM   5433  C CG1 . ILE D 2 13  ? -52.509  -12.809 15.447  1.00 49.96  ? 13  ILE D CG1 1 
ATOM   5434  C CG2 . ILE D 2 13  ? -50.617  -11.674 16.661  1.00 48.70  ? 13  ILE D CG2 1 
ATOM   5435  C CD1 . ILE D 2 13  ? -52.208  -14.293 15.464  1.00 48.27  ? 13  ILE D CD1 1 
ATOM   5436  N N   . THR D 2 14  ? -50.973  -10.965 12.334  1.00 45.25  ? 14  THR D N   1 
ATOM   5437  C CA  . THR D 2 14  ? -51.179  -11.378 10.962  1.00 45.53  ? 14  THR D CA  1 
ATOM   5438  C C   . THR D 2 14  ? -51.183  -12.906 10.872  1.00 43.83  ? 14  THR D C   1 
ATOM   5439  O O   . THR D 2 14  ? -50.539  -13.590 11.667  1.00 45.23  ? 14  THR D O   1 
ATOM   5440  C CB  . THR D 2 14  ? -50.095  -10.777 10.068  1.00 50.21  ? 14  THR D CB  1 
ATOM   5441  O OG1 . THR D 2 14  ? -48.814  -11.351 10.378  1.00 51.97  ? 14  THR D OG1 1 
ATOM   5442  C CG2 . THR D 2 14  ? -50.026  -9.292  10.296  1.00 50.68  ? 14  THR D CG2 1 
ATOM   5443  N N   . LEU D 2 15  ? -51.881  -13.396 9.851   1.00 35.61  ? 15  LEU D N   1 
ATOM   5444  C CA  . LEU D 2 15  ? -51.977  -14.847 9.602   1.00 43.74  ? 15  LEU D CA  1 
ATOM   5445  C C   . LEU D 2 15  ? -51.937  -15.093 8.095   1.00 54.27  ? 15  LEU D C   1 
ATOM   5446  O O   . LEU D 2 15  ? -52.683  -14.422 7.383   1.00 54.15  ? 15  LEU D O   1 
ATOM   5447  C CB  . LEU D 2 15  ? -53.309  -15.336 10.172  1.00 48.80  ? 15  LEU D CB  1 
ATOM   5448  C CG  . LEU D 2 15  ? -53.254  -16.339 11.324  1.00 57.79  ? 15  LEU D CG  1 
ATOM   5449  C CD1 . LEU D 2 15  ? -54.332  -17.392 11.152  1.00 50.94  ? 15  LEU D CD1 1 
ATOM   5450  C CD2 . LEU D 2 15  ? -51.888  -16.994 11.437  1.00 47.21  ? 15  LEU D CD2 1 
ATOM   5451  N N   . GLU D 2 16  ? -51.086  -16.004 7.625   1.00 53.34  ? 16  GLU D N   1 
ATOM   5452  C CA  . GLU D 2 16  ? -51.066  -16.392 6.217   1.00 56.96  ? 16  GLU D CA  1 
ATOM   5453  C C   . GLU D 2 16  ? -52.039  -17.553 6.022   1.00 58.57  ? 16  GLU D C   1 
ATOM   5454  O O   . GLU D 2 16  ? -51.861  -18.621 6.620   1.00 60.40  ? 16  GLU D O   1 
ATOM   5455  C CB  . GLU D 2 16  ? -49.665  -16.775 5.747   1.00 49.42  ? 16  GLU D CB  1 
ATOM   5456  C CG  . GLU D 2 16  ? -49.084  -15.809 4.729   1.00 55.49  ? 16  GLU D CG  1 
ATOM   5457  C CD  . GLU D 2 16  ? -49.828  -15.812 3.400   1.00 60.72  ? 16  GLU D CD  1 
ATOM   5458  O OE1 . GLU D 2 16  ? -49.708  -14.800 2.675   1.00 67.05  ? 16  GLU D OE1 1 
ATOM   5459  O OE2 . GLU D 2 16  ? -50.527  -16.804 3.075   1.00 58.01  ? 16  GLU D OE2 1 
ATOM   5460  N N   . VAL D 2 17  ? -53.089  -17.329 5.228   1.00 48.44  ? 17  VAL D N   1 
ATOM   5461  C CA  . VAL D 2 17  ? -54.070  -18.350 4.902   1.00 51.12  ? 17  VAL D CA  1 
ATOM   5462  C C   . VAL D 2 17  ? -54.435  -18.191 3.433   1.00 53.31  ? 17  VAL D C   1 
ATOM   5463  O O   . VAL D 2 17  ? -53.939  -17.297 2.745   1.00 53.68  ? 17  VAL D O   1 
ATOM   5464  C CB  . VAL D 2 17  ? -55.340  -18.261 5.776   1.00 54.09  ? 17  VAL D CB  1 
ATOM   5465  C CG1 . VAL D 2 17  ? -55.010  -18.304 7.260   1.00 56.34  ? 17  VAL D CG1 1 
ATOM   5466  C CG2 . VAL D 2 17  ? -56.100  -16.999 5.453   1.00 58.29  ? 17  VAL D CG2 1 
ATOM   5467  N N   . GLU D 2 18  ? -55.327  -19.050 2.961   1.00 47.13  ? 18  GLU D N   1 
ATOM   5468  C CA  . GLU D 2 18  ? -55.762  -19.065 1.574   1.00 55.02  ? 18  GLU D CA  1 
ATOM   5469  C C   . GLU D 2 18  ? -57.269  -19.274 1.537   1.00 57.41  ? 18  GLU D C   1 
ATOM   5470  O O   . GLU D 2 18  ? -57.821  -19.956 2.410   1.00 60.34  ? 18  GLU D O   1 
ATOM   5471  C CB  . GLU D 2 18  ? -55.060  -20.179 0.762   1.00 55.00  ? 18  GLU D CB  1 
ATOM   5472  C CG  . GLU D 2 18  ? -53.527  -20.101 0.752   1.00 52.44  ? 18  GLU D CG  1 
ATOM   5473  C CD  . GLU D 2 18  ? -52.989  -19.036 -0.200  1.00 65.03  ? 18  GLU D CD  1 
ATOM   5474  O OE1 . GLU D 2 18  ? -51.995  -18.340 0.167   1.00 65.69  ? 18  GLU D OE1 1 
ATOM   5475  O OE2 . GLU D 2 18  ? -53.563  -18.903 -1.319  1.00 55.14  ? 18  GLU D OE2 1 
ATOM   5476  N N   . PRO D 2 19  ? -57.958  -18.710 0.536   1.00 49.80  ? 19  PRO D N   1 
ATOM   5477  C CA  . PRO D 2 19  ? -59.419  -18.862 0.447   1.00 52.33  ? 19  PRO D CA  1 
ATOM   5478  C C   . PRO D 2 19  ? -59.949  -20.255 0.729   1.00 58.81  ? 19  PRO D C   1 
ATOM   5479  O O   . PRO D 2 19  ? -60.973  -20.388 1.409   1.00 62.07  ? 19  PRO D O   1 
ATOM   5480  C CB  . PRO D 2 19  ? -59.704  -18.461 -0.999  1.00 51.86  ? 19  PRO D CB  1 
ATOM   5481  C CG  . PRO D 2 19  ? -58.649  -17.514 -1.335  1.00 45.01  ? 19  PRO D CG  1 
ATOM   5482  C CD  . PRO D 2 19  ? -57.431  -17.873 -0.550  1.00 48.94  ? 19  PRO D CD  1 
ATOM   5483  N N   . SER D 2 20  ? -59.290  -21.300 0.231   1.00 61.88  ? 20  SER D N   1 
ATOM   5484  C CA  . SER D 2 20  ? -59.841  -22.647 0.368   1.00 63.64  ? 20  SER D CA  1 
ATOM   5485  C C   . SER D 2 20  ? -59.712  -23.221 1.781   1.00 64.50  ? 20  SER D C   1 
ATOM   5486  O O   . SER D 2 20  ? -60.319  -24.263 2.054   1.00 63.82  ? 20  SER D O   1 
ATOM   5487  C CB  . SER D 2 20  ? -59.159  -23.577 -0.631  1.00 60.68  ? 20  SER D CB  1 
ATOM   5488  O OG  . SER D 2 20  ? -57.767  -23.648 -0.362  1.00 63.46  ? 20  SER D OG  1 
ATOM   5489  N N   . ASP D 2 21  ? -58.953  -22.574 2.676   1.00 59.88  ? 21  ASP D N   1 
ATOM   5490  C CA  . ASP D 2 21  ? -58.724  -23.105 4.016   1.00 57.37  ? 21  ASP D CA  1 
ATOM   5491  C C   . ASP D 2 21  ? -60.033  -23.247 4.779   1.00 62.37  ? 21  ASP D C   1 
ATOM   5492  O O   . ASP D 2 21  ? -60.839  -22.316 4.837   1.00 62.29  ? 21  ASP D O   1 
ATOM   5493  C CB  . ASP D 2 21  ? -57.783  -22.192 4.798   1.00 54.54  ? 21  ASP D CB  1 
ATOM   5494  C CG  . ASP D 2 21  ? -56.340  -22.314 4.358   1.00 55.66  ? 21  ASP D CG  1 
ATOM   5495  O OD1 . ASP D 2 21  ? -56.019  -23.298 3.659   1.00 62.96  ? 21  ASP D OD1 1 
ATOM   5496  O OD2 . ASP D 2 21  ? -55.520  -21.431 4.712   1.00 51.57  ? 21  ASP D OD2 1 
ATOM   5497  N N   . THR D 2 22  ? -60.199  -24.400 5.408   1.00 70.44  ? 22  THR D N   1 
ATOM   5498  C CA  . THR D 2 22  ? -61.396  -24.609 6.248   1.00 64.99  ? 22  THR D CA  1 
ATOM   5499  C C   . THR D 2 22  ? -61.206  -23.847 7.553   1.00 64.47  ? 22  THR D C   1 
ATOM   5500  O O   . THR D 2 22  ? -60.059  -23.526 7.908   1.00 64.12  ? 22  THR D O   1 
ATOM   5501  C CB  . THR D 2 22  ? -61.631  -26.101 6.486   1.00 62.64  ? 22  THR D CB  1 
ATOM   5502  O OG1 . THR D 2 22  ? -60.530  -26.614 7.227   1.00 57.28  ? 22  THR D OG1 1 
ATOM   5503  C CG2 . THR D 2 22  ? -61.786  -26.880 5.200   1.00 66.04  ? 22  THR D CG2 1 
ATOM   5504  N N   . ILE D 2 23  ? -62.302  -23.603 8.255   1.00 58.32  ? 23  ILE D N   1 
ATOM   5505  C CA  . ILE D 2 23  ? -62.219  -22.853 9.536   1.00 61.87  ? 23  ILE D CA  1 
ATOM   5506  C C   . ILE D 2 23  ? -61.312  -23.640 10.493  1.00 65.38  ? 23  ILE D C   1 
ATOM   5507  O O   . ILE D 2 23  ? -60.539  -22.998 11.215  1.00 66.37  ? 23  ILE D O   1 
ATOM   5508  C CB  . ILE D 2 23  ? -63.635  -22.585 10.080  1.00 58.97  ? 23  ILE D CB  1 
ATOM   5509  C CG1 . ILE D 2 23  ? -64.476  -21.766 9.096   1.00 56.08  ? 23  ILE D CG1 1 
ATOM   5510  C CG2 . ILE D 2 23  ? -63.586  -21.945 11.456  1.00 50.56  ? 23  ILE D CG2 1 
ATOM   5511  C CD1 . ILE D 2 23  ? -63.726  -20.663 8.389   1.00 56.84  ? 23  ILE D CD1 1 
ATOM   5512  N N   . GLU D 2 24  ? -61.347  -24.976 10.444  1.00 60.88  ? 24  GLU D N   1 
ATOM   5513  C CA  . GLU D 2 24  ? -60.472  -25.816 11.309  1.00 61.09  ? 24  GLU D CA  1 
ATOM   5514  C C   . GLU D 2 24  ? -58.994  -25.628 10.947  1.00 63.30  ? 24  GLU D C   1 
ATOM   5515  O O   . GLU D 2 24  ? -58.184  -25.663 11.879  1.00 64.80  ? 24  GLU D O   1 
ATOM   5516  C CB  . GLU D 2 24  ? -60.879  -27.293 11.317  1.00 59.12  ? 24  GLU D CB  1 
ATOM   5517  C CG  . GLU D 2 24  ? -61.360  -27.851 10.001  1.00 64.77  ? 24  GLU D CG  1 
ATOM   5518  C CD  . GLU D 2 24  ? -62.856  -27.729 9.804   1.00 67.96  ? 24  GLU D CD  1 
ATOM   5519  O OE1 . GLU D 2 24  ? -63.291  -26.651 9.381   1.00 67.69  ? 24  GLU D OE1 1 
ATOM   5520  O OE2 . GLU D 2 24  ? -63.574  -28.701 10.087  1.00 69.14  ? 24  GLU D OE2 1 
ATOM   5521  N N   . ASN D 2 25  ? -58.640  -25.438 9.671   1.00 59.14  ? 25  ASN D N   1 
ATOM   5522  C CA  . ASN D 2 25  ? -57.228  -25.152 9.386   1.00 66.13  ? 25  ASN D CA  1 
ATOM   5523  C C   . ASN D 2 25  ? -56.802  -23.797 9.927   1.00 59.46  ? 25  ASN D C   1 
ATOM   5524  O O   . ASN D 2 25  ? -55.648  -23.632 10.334  1.00 57.15  ? 25  ASN D O   1 
ATOM   5525  C CB  . ASN D 2 25  ? -56.918  -25.203 7.891   1.00 65.10  ? 25  ASN D CB  1 
ATOM   5526  C CG  . ASN D 2 25  ? -57.480  -26.433 7.224   1.00 77.59  ? 25  ASN D CG  1 
ATOM   5527  O OD1 . ASN D 2 25  ? -58.055  -27.315 7.884   1.00 80.39  ? 25  ASN D OD1 1 
ATOM   5528  N ND2 . ASN D 2 25  ? -57.335  -26.501 5.900   1.00 74.17  ? 25  ASN D ND2 1 
ATOM   5529  N N   . VAL D 2 26  ? -57.698  -22.810 9.924   1.00 59.57  ? 26  VAL D N   1 
ATOM   5530  C CA  . VAL D 2 26  ? -57.304  -21.498 10.422  1.00 59.58  ? 26  VAL D CA  1 
ATOM   5531  C C   . VAL D 2 26  ? -57.137  -21.540 11.935  1.00 60.07  ? 26  VAL D C   1 
ATOM   5532  O O   . VAL D 2 26  ? -56.172  -20.979 12.485  1.00 55.20  ? 26  VAL D O   1 
ATOM   5533  C CB  . VAL D 2 26  ? -58.312  -20.421 9.972   1.00 60.47  ? 26  VAL D CB  1 
ATOM   5534  C CG1 . VAL D 2 26  ? -57.998  -19.062 10.613  1.00 50.44  ? 26  VAL D CG1 1 
ATOM   5535  C CG2 . VAL D 2 26  ? -58.305  -20.290 8.454   1.00 58.76  ? 26  VAL D CG2 1 
ATOM   5536  N N   . LYS D 2 27  ? -58.061  -22.217 12.634  1.00 52.23  ? 27  LYS D N   1 
ATOM   5537  C CA  . LYS D 2 27  ? -57.885  -22.417 14.069  1.00 53.65  ? 27  LYS D CA  1 
ATOM   5538  C C   . LYS D 2 27  ? -56.547  -23.088 14.346  1.00 55.18  ? 27  LYS D C   1 
ATOM   5539  O O   . LYS D 2 27  ? -55.794  -22.666 15.230  1.00 51.12  ? 27  LYS D O   1 
ATOM   5540  C CB  . LYS D 2 27  ? -59.031  -23.255 14.631  1.00 57.96  ? 27  LYS D CB  1 
ATOM   5541  C CG  . LYS D 2 27  ? -60.342  -22.515 14.877  1.00 57.35  ? 27  LYS D CG  1 
ATOM   5542  C CD  . LYS D 2 27  ? -61.530  -23.462 14.714  1.00 57.54  ? 27  LYS D CD  1 
ATOM   5543  C CE  . LYS D 2 27  ? -62.760  -22.994 15.478  1.00 57.12  ? 27  LYS D CE  1 
ATOM   5544  N NZ  . LYS D 2 27  ? -63.968  -23.858 15.255  1.00 51.32  ? 27  LYS D NZ  1 
ATOM   5545  N N   . ALA D 2 28  ? -56.233  -24.134 13.577  1.00 57.80  ? 28  ALA D N   1 
ATOM   5546  C CA  . ALA D 2 28  ? -54.898  -24.716 13.598  1.00 54.92  ? 28  ALA D CA  1 
ATOM   5547  C C   . ALA D 2 28  ? -53.832  -23.642 13.407  1.00 48.69  ? 28  ALA D C   1 
ATOM   5548  O O   . ALA D 2 28  ? -52.964  -23.456 14.263  1.00 49.67  ? 28  ALA D O   1 
ATOM   5549  C CB  . ALA D 2 28  ? -54.790  -25.800 12.523  1.00 50.63  ? 28  ALA D CB  1 
ATOM   5550  N N   . LYS D 2 29  ? -53.894  -22.904 12.297  1.00 49.33  ? 29  LYS D N   1 
ATOM   5551  C CA  . LYS D 2 29  ? -52.888  -21.865 12.068  1.00 55.11  ? 29  LYS D CA  1 
ATOM   5552  C C   . LYS D 2 29  ? -52.844  -20.863 13.221  1.00 54.27  ? 29  LYS D C   1 
ATOM   5553  O O   . LYS D 2 29  ? -51.762  -20.365 13.576  1.00 45.17  ? 29  LYS D O   1 
ATOM   5554  C CB  . LYS D 2 29  ? -53.145  -21.162 10.729  1.00 53.44  ? 29  LYS D CB  1 
ATOM   5555  N N   . ILE D 2 30  ? -53.993  -20.593 13.853  1.00 55.36  ? 30  ILE D N   1 
ATOM   5556  C CA  . ILE D 2 30  ? -53.998  -19.691 15.005  1.00 52.55  ? 30  ILE D CA  1 
ATOM   5557  C C   . ILE D 2 30  ? -53.225  -20.306 16.164  1.00 46.70  ? 30  ILE D C   1 
ATOM   5558  O O   . ILE D 2 30  ? -52.319  -19.670 16.714  1.00 50.23  ? 30  ILE D O   1 
ATOM   5559  C CB  . ILE D 2 30  ? -55.440  -19.303 15.398  1.00 53.52  ? 30  ILE D CB  1 
ATOM   5560  C CG1 . ILE D 2 30  ? -56.028  -18.376 14.337  1.00 52.04  ? 30  ILE D CG1 1 
ATOM   5561  C CG2 . ILE D 2 30  ? -55.486  -18.574 16.741  1.00 46.24  ? 30  ILE D CG2 1 
ATOM   5562  C CD1 . ILE D 2 30  ? -57.360  -17.838 14.681  1.00 54.22  ? 30  ILE D CD1 1 
ATOM   5563  N N   . GLN D 2 31  ? -53.552  -21.560 16.530  1.00 47.82  ? 31  GLN D N   1 
ATOM   5564  C CA  . GLN D 2 31  ? -52.810  -22.270 17.585  1.00 54.44  ? 31  GLN D CA  1 
ATOM   5565  C C   . GLN D 2 31  ? -51.323  -22.281 17.293  1.00 50.35  ? 31  GLN D C   1 
ATOM   5566  O O   . GLN D 2 31  ? -50.505  -22.069 18.195  1.00 45.01  ? 31  GLN D O   1 
ATOM   5567  C CB  . GLN D 2 31  ? -53.297  -23.710 17.736  1.00 54.57  ? 31  GLN D CB  1 
ATOM   5568  N N   . ASP D 2 32  ? -50.965  -22.516 16.027  1.00 46.72  ? 32  ASP D N   1 
ATOM   5569  C CA  . ASP D 2 32  ? -49.587  -22.379 15.575  1.00 48.77  ? 32  ASP D CA  1 
ATOM   5570  C C   . ASP D 2 32  ? -48.951  -21.075 16.060  1.00 56.16  ? 32  ASP D C   1 
ATOM   5571  O O   . ASP D 2 32  ? -47.830  -21.079 16.592  1.00 52.80  ? 32  ASP D O   1 
ATOM   5572  C CB  . ASP D 2 32  ? -49.558  -22.465 14.052  1.00 50.71  ? 32  ASP D CB  1 
ATOM   5573  C CG  . ASP D 2 32  ? -48.228  -22.940 13.513  1.00 55.10  ? 32  ASP D CG  1 
ATOM   5574  O OD1 . ASP D 2 32  ? -47.864  -24.109 13.807  1.00 60.29  ? 32  ASP D OD1 1 
ATOM   5575  O OD2 . ASP D 2 32  ? -47.571  -22.154 12.776  1.00 54.13  ? 32  ASP D OD2 1 
ATOM   5576  N N   . LYS D 2 33  ? -49.661  -19.940 15.903  1.00 56.57  ? 33  LYS D N   1 
ATOM   5577  C CA  . LYS D 2 33  ? -49.060  -18.642 16.209  1.00 50.95  ? 33  LYS D CA  1 
ATOM   5578  C C   . LYS D 2 33  ? -49.357  -18.122 17.608  1.00 55.96  ? 33  LYS D C   1 
ATOM   5579  O O   . LYS D 2 33  ? -48.545  -17.349 18.134  1.00 56.65  ? 33  LYS D O   1 
ATOM   5580  C CB  . LYS D 2 33  ? -49.493  -17.584 15.188  1.00 51.11  ? 33  LYS D CB  1 
ATOM   5581  C CG  . LYS D 2 33  ? -48.491  -16.444 15.004  1.00 43.14  ? 33  LYS D CG  1 
ATOM   5582  C CD  . LYS D 2 33  ? -48.701  -15.699 13.682  1.00 42.88  ? 33  LYS D CD  1 
ATOM   5583  C CE  . LYS D 2 33  ? -47.810  -14.435 13.573  1.00 46.95  ? 33  LYS D CE  1 
ATOM   5584  N NZ  . LYS D 2 33  ? -47.910  -13.676 12.251  1.00 45.88  ? 33  LYS D NZ  1 
ATOM   5585  N N   . GLU D 2 34  ? -50.468  -18.533 18.239  1.00 54.54  ? 34  GLU D N   1 
ATOM   5586  C CA  . GLU D 2 34  ? -50.871  -17.942 19.515  1.00 59.52  ? 34  GLU D CA  1 
ATOM   5587  C C   . GLU D 2 34  ? -51.074  -18.924 20.658  1.00 62.05  ? 34  GLU D C   1 
ATOM   5588  O O   . GLU D 2 34  ? -51.533  -18.501 21.724  1.00 66.00  ? 34  GLU D O   1 
ATOM   5589  C CB  . GLU D 2 34  ? -52.163  -17.131 19.345  1.00 56.50  ? 34  GLU D CB  1 
ATOM   5590  C CG  . GLU D 2 34  ? -51.930  -15.740 18.838  1.00 55.26  ? 34  GLU D CG  1 
ATOM   5591  C CD  . GLU D 2 34  ? -51.477  -14.814 19.919  1.00 63.20  ? 34  GLU D CD  1 
ATOM   5592  O OE1 . GLU D 2 34  ? -52.251  -14.599 20.886  1.00 59.89  ? 34  GLU D OE1 1 
ATOM   5593  O OE2 . GLU D 2 34  ? -50.343  -14.297 19.797  1.00 72.04  ? 34  GLU D OE2 1 
ATOM   5594  N N   . GLY D 2 35  ? -50.789  -20.209 20.476  1.00 54.85  ? 35  GLY D N   1 
ATOM   5595  C CA  . GLY D 2 35  ? -50.854  -21.122 21.597  1.00 53.03  ? 35  GLY D CA  1 
ATOM   5596  C C   . GLY D 2 35  ? -52.236  -21.387 22.161  1.00 63.74  ? 35  GLY D C   1 
ATOM   5597  O O   . GLY D 2 35  ? -52.358  -21.650 23.361  1.00 70.76  ? 35  GLY D O   1 
ATOM   5598  N N   . ILE D 2 36  ? -53.278  -21.341 21.341  1.00 61.64  ? 36  ILE D N   1 
ATOM   5599  C CA  . ILE D 2 36  ? -54.659  -21.574 21.779  1.00 60.37  ? 36  ILE D CA  1 
ATOM   5600  C C   . ILE D 2 36  ? -55.161  -22.852 21.120  1.00 59.27  ? 36  ILE D C   1 
ATOM   5601  O O   . ILE D 2 36  ? -55.150  -22.942 19.891  1.00 62.97  ? 36  ILE D O   1 
ATOM   5602  C CB  . ILE D 2 36  ? -55.590  -20.397 21.417  1.00 62.11  ? 36  ILE D CB  1 
ATOM   5603  C CG1 . ILE D 2 36  ? -54.874  -19.045 21.494  1.00 63.25  ? 36  ILE D CG1 1 
ATOM   5604  C CG2 . ILE D 2 36  ? -56.816  -20.397 22.294  1.00 62.09  ? 36  ILE D CG2 1 
ATOM   5605  C CD1 . ILE D 2 36  ? -54.522  -18.607 22.868  1.00 54.38  ? 36  ILE D CD1 1 
ATOM   5606  N N   . PRO D 2 37  ? -55.627  -23.840 21.875  1.00 59.59  ? 37  PRO D N   1 
ATOM   5607  C CA  . PRO D 2 37  ? -56.137  -25.076 21.259  1.00 59.19  ? 37  PRO D CA  1 
ATOM   5608  C C   . PRO D 2 37  ? -57.353  -24.797 20.396  1.00 62.05  ? 37  PRO D C   1 
ATOM   5609  O O   . PRO D 2 37  ? -58.273  -24.083 20.823  1.00 66.54  ? 37  PRO D O   1 
ATOM   5610  C CB  . PRO D 2 37  ? -56.512  -25.945 22.464  1.00 57.74  ? 37  PRO D CB  1 
ATOM   5611  C CG  . PRO D 2 37  ? -55.766  -25.372 23.594  1.00 56.66  ? 37  PRO D CG  1 
ATOM   5612  C CD  . PRO D 2 37  ? -55.636  -23.909 23.341  1.00 61.56  ? 37  PRO D CD  1 
ATOM   5613  N N   . PRO D 2 38  ? -57.408  -25.364 19.183  1.00 57.78  ? 38  PRO D N   1 
ATOM   5614  C CA  . PRO D 2 38  ? -58.563  -25.138 18.306  1.00 55.50  ? 38  PRO D CA  1 
ATOM   5615  C C   . PRO D 2 38  ? -59.901  -25.435 18.958  1.00 59.22  ? 38  PRO D C   1 
ATOM   5616  O O   . PRO D 2 38  ? -60.952  -25.032 18.450  1.00 59.47  ? 38  PRO D O   1 
ATOM   5617  C CB  . PRO D 2 38  ? -58.303  -26.100 17.141  1.00 53.18  ? 38  PRO D CB  1 
ATOM   5618  C CG  . PRO D 2 38  ? -56.834  -26.202 17.073  1.00 57.66  ? 38  PRO D CG  1 
ATOM   5619  C CD  . PRO D 2 38  ? -56.333  -26.103 18.500  1.00 55.67  ? 38  PRO D CD  1 
ATOM   5620  N N   . ASP D 2 39  ? -59.885  -26.142 20.083  1.00 62.70  ? 39  ASP D N   1 
ATOM   5621  C CA  . ASP D 2 39  ? -61.150  -26.547 20.669  1.00 65.07  ? 39  ASP D CA  1 
ATOM   5622  C C   . ASP D 2 39  ? -61.833  -25.417 21.422  1.00 58.32  ? 39  ASP D C   1 
ATOM   5623  O O   . ASP D 2 39  ? -63.043  -25.477 21.634  1.00 53.09  ? 39  ASP D O   1 
ATOM   5624  C CB  . ASP D 2 39  ? -60.937  -27.763 21.570  1.00 68.09  ? 39  ASP D CB  1 
ATOM   5625  C CG  . ASP D 2 39  ? -61.166  -29.067 20.827  1.00 76.60  ? 39  ASP D CG  1 
ATOM   5626  O OD1 . ASP D 2 39  ? -61.129  -29.036 19.573  1.00 74.35  ? 39  ASP D OD1 1 
ATOM   5627  O OD2 . ASP D 2 39  ? -61.392  -30.112 21.483  1.00 81.66  ? 39  ASP D OD2 1 
ATOM   5628  N N   . GLN D 2 40  ? -61.110  -24.371 21.790  1.00 60.83  ? 40  GLN D N   1 
ATOM   5629  C CA  . GLN D 2 40  ? -61.714  -23.274 22.527  1.00 63.96  ? 40  GLN D CA  1 
ATOM   5630  C C   . GLN D 2 40  ? -61.773  -21.970 21.747  1.00 57.65  ? 40  GLN D C   1 
ATOM   5631  O O   . GLN D 2 40  ? -62.340  -20.999 22.253  1.00 50.98  ? 40  GLN D O   1 
ATOM   5632  C CB  . GLN D 2 40  ? -60.964  -23.046 23.835  1.00 72.02  ? 40  GLN D CB  1 
ATOM   5633  C CG  . GLN D 2 40  ? -60.766  -24.307 24.626  1.00 68.93  ? 40  GLN D CG  1 
ATOM   5634  C CD  . GLN D 2 40  ? -59.571  -24.210 25.510  1.00 67.58  ? 40  GLN D CD  1 
ATOM   5635  O OE1 . GLN D 2 40  ? -58.624  -24.986 25.376  1.00 74.57  ? 40  GLN D OE1 1 
ATOM   5636  N NE2 . GLN D 2 40  ? -59.594  -23.249 26.425  1.00 61.83  ? 40  GLN D NE2 1 
ATOM   5637  N N   . GLN D 2 41  ? -61.209  -21.925 20.538  1.00 58.81  ? 41  GLN D N   1 
ATOM   5638  C CA  . GLN D 2 41  ? -61.254  -20.723 19.717  1.00 54.34  ? 41  GLN D CA  1 
ATOM   5639  C C   . GLN D 2 41  ? -62.641  -20.514 19.131  1.00 53.43  ? 41  GLN D C   1 
ATOM   5640  O O   . GLN D 2 41  ? -63.299  -21.451 18.683  1.00 54.16  ? 41  GLN D O   1 
ATOM   5641  C CB  . GLN D 2 41  ? -60.268  -20.827 18.577  1.00 52.02  ? 41  GLN D CB  1 
ATOM   5642  C CG  . GLN D 2 41  ? -58.840  -20.758 18.961  1.00 53.39  ? 41  GLN D CG  1 
ATOM   5643  C CD  . GLN D 2 41  ? -57.964  -21.008 17.768  1.00 50.28  ? 41  GLN D CD  1 
ATOM   5644  O OE1 . GLN D 2 41  ? -58.370  -20.774 16.640  1.00 48.87  ? 41  GLN D OE1 1 
ATOM   5645  N NE2 . GLN D 2 41  ? -56.765  -21.506 18.004  1.00 56.70  ? 41  GLN D NE2 1 
ATOM   5646  N N   . ARG D 2 42  ? -63.060  -19.256 19.092  1.00 55.80  ? 42  ARG D N   1 
ATOM   5647  C CA  . ARG D 2 42  ? -64.336  -18.905 18.428  1.00 57.55  ? 42  ARG D CA  1 
ATOM   5648  C C   . ARG D 2 42  ? -64.019  -17.706 17.538  1.00 56.05  ? 42  ARG D C   1 
ATOM   5649  O O   . ARG D 2 42  ? -63.647  -16.661 18.071  1.00 53.85  ? 42  ARG D O   1 
ATOM   5650  C CB  . ARG D 2 42  ? -65.452  -18.673 19.443  1.00 58.57  ? 42  ARG D CB  1 
ATOM   5651  C CG  . ARG D 2 42  ? -65.784  -19.879 20.310  1.00 57.79  ? 42  ARG D CG  1 
ATOM   5652  C CD  . ARG D 2 42  ? -66.987  -19.625 21.185  1.00 58.79  ? 42  ARG D CD  1 
ATOM   5653  N NE  . ARG D 2 42  ? -67.783  -18.588 20.570  1.00 59.25  ? 42  ARG D NE  1 
ATOM   5654  C CZ  . ARG D 2 42  ? -68.199  -17.487 21.165  1.00 55.91  ? 42  ARG D CZ  1 
ATOM   5655  N NH1 . ARG D 2 42  ? -67.943  -17.269 22.442  1.00 51.90  ? 42  ARG D NH1 1 
ATOM   5656  N NH2 . ARG D 2 42  ? -68.895  -16.620 20.464  1.00 53.31  ? 42  ARG D NH2 1 
ATOM   5657  N N   . LEU D 2 43  ? -64.178  -17.861 16.233  1.00 56.05  ? 43  LEU D N   1 
ATOM   5658  C CA  . LEU D 2 43  ? -63.771  -16.859 15.264  1.00 54.20  ? 43  LEU D CA  1 
ATOM   5659  C C   . LEU D 2 43  ? -65.004  -16.067 14.848  1.00 48.97  ? 43  LEU D C   1 
ATOM   5660  O O   . LEU D 2 43  ? -65.893  -16.590 14.163  1.00 45.95  ? 43  LEU D O   1 
ATOM   5661  C CB  . LEU D 2 43  ? -63.085  -17.526 14.077  1.00 47.93  ? 43  LEU D CB  1 
ATOM   5662  C CG  . LEU D 2 43  ? -61.841  -18.280 14.532  1.00 48.07  ? 43  LEU D CG  1 
ATOM   5663  C CD1 . LEU D 2 43  ? -61.415  -19.251 13.488  1.00 43.93  ? 43  LEU D CD1 1 
ATOM   5664  C CD2 . LEU D 2 43  ? -60.724  -17.303 14.817  1.00 43.46  ? 43  LEU D CD2 1 
ATOM   5665  N N   . ILE D 2 44  ? -65.064  -14.812 15.272  1.00 49.06  ? 44  ILE D N   1 
ATOM   5666  C CA  . ILE D 2 44  ? -66.149  -13.919 14.872  1.00 55.52  ? 44  ILE D CA  1 
ATOM   5667  C C   . ILE D 2 44  ? -65.690  -13.084 13.689  1.00 49.52  ? 44  ILE D C   1 
ATOM   5668  O O   . ILE D 2 44  ? -64.639  -12.432 13.742  1.00 49.76  ? 44  ILE D O   1 
ATOM   5669  C CB  . ILE D 2 44  ? -66.603  -13.013 16.025  1.00 49.50  ? 44  ILE D CB  1 
ATOM   5670  C CG1 . ILE D 2 44  ? -66.751  -13.833 17.314  1.00 54.39  ? 44  ILE D CG1 1 
ATOM   5671  C CG2 . ILE D 2 44  ? -67.891  -12.346 15.644  1.00 39.18  ? 44  ILE D CG2 1 
ATOM   5672  C CD1 . ILE D 2 44  ? -67.564  -15.123 17.142  1.00 50.86  ? 44  ILE D CD1 1 
ATOM   5673  N N   . PHE D 2 45  ? -66.473  -13.109 12.621  1.00 46.15  ? 45  PHE D N   1 
ATOM   5674  C CA  . PHE D 2 45  ? -66.260  -12.211 11.500  1.00 48.98  ? 45  PHE D CA  1 
ATOM   5675  C C   . PHE D 2 45  ? -67.602  -11.756 10.956  1.00 51.70  ? 45  PHE D C   1 
ATOM   5676  O O   . PHE D 2 45  ? -68.435  -12.591 10.586  1.00 51.64  ? 45  PHE D O   1 
ATOM   5677  C CB  . PHE D 2 45  ? -65.461  -12.881 10.398  1.00 47.37  ? 45  PHE D CB  1 
ATOM   5678  C CG  . PHE D 2 45  ? -65.375  -12.077 9.157   1.00 45.31  ? 45  PHE D CG  1 
ATOM   5679  C CD1 . PHE D 2 45  ? -64.432  -11.062 9.046   1.00 52.66  ? 45  PHE D CD1 1 
ATOM   5680  C CD2 . PHE D 2 45  ? -66.213  -12.335 8.087   1.00 43.19  ? 45  PHE D CD2 1 
ATOM   5681  C CE1 . PHE D 2 45  ? -64.330  -10.304 7.885   1.00 49.59  ? 45  PHE D CE1 1 
ATOM   5682  C CE2 . PHE D 2 45  ? -66.117  -11.590 6.928   1.00 44.27  ? 45  PHE D CE2 1 
ATOM   5683  C CZ  . PHE D 2 45  ? -65.170  -10.576 6.826   1.00 44.21  ? 45  PHE D CZ  1 
ATOM   5684  N N   . ALA D 2 46  ? -67.799  -10.433 10.908  1.00 54.26  ? 46  ALA D N   1 
ATOM   5685  C CA  . ALA D 2 46  ? -68.979  -9.831  10.284  1.00 48.09  ? 46  ALA D CA  1 
ATOM   5686  C C   . ALA D 2 46  ? -70.256  -10.328 10.944  1.00 46.30  ? 46  ALA D C   1 
ATOM   5687  O O   . ALA D 2 46  ? -71.262  -10.572 10.286  1.00 54.91  ? 46  ALA D O   1 
ATOM   5688  C CB  . ALA D 2 46  ? -69.010  -10.107 8.783   1.00 44.50  ? 46  ALA D CB  1 
ATOM   5689  N N   . GLY D 2 47  ? -70.207  -10.530 12.256  1.00 44.77  ? 47  GLY D N   1 
ATOM   5690  C CA  . GLY D 2 47  ? -71.402  -10.959 13.001  1.00 47.55  ? 47  GLY D CA  1 
ATOM   5691  C C   . GLY D 2 47  ? -71.635  -12.447 12.968  1.00 49.88  ? 47  GLY D C   1 
ATOM   5692  O O   . GLY D 2 47  ? -72.475  -12.920 13.735  1.00 55.04  ? 47  GLY D O   1 
ATOM   5693  N N   . LYS D 2 48  ? -70.936  -13.156 12.093  1.00 47.35  ? 48  LYS D N   1 
ATOM   5694  C CA  . LYS D 2 48  ? -71.052  -14.600 12.049  1.00 47.38  ? 48  LYS D CA  1 
ATOM   5695  C C   . LYS D 2 48  ? -69.911  -15.231 12.838  1.00 48.75  ? 48  LYS D C   1 
ATOM   5696  O O   . LYS D 2 48  ? -68.807  -14.684 12.928  1.00 51.10  ? 48  LYS D O   1 
ATOM   5697  C CB  . LYS D 2 48  ? -71.057  -15.100 10.593  1.00 40.93  ? 48  LYS D CB  1 
ATOM   5698  N N   . GLN D 2 49  ? -70.185  -16.409 13.384  1.00 44.58  ? 49  GLN D N   1 
ATOM   5699  C CA  . GLN D 2 49  ? -69.105  -17.197 14.011  1.00 49.84  ? 49  GLN D CA  1 
ATOM   5700  C C   . GLN D 2 49  ? -68.723  -18.241 12.973  1.00 47.56  ? 49  GLN D C   1 
ATOM   5701  O O   . GLN D 2 49  ? -69.604  -19.002 12.554  1.00 49.46  ? 49  GLN D O   1 
ATOM   5702  C CB  . GLN D 2 49  ? -69.558  -17.885 15.293  1.00 53.17  ? 49  GLN D CB  1 
ATOM   5703  C CG  . GLN D 2 49  ? -68.460  -18.689 15.971  1.00 53.70  ? 49  GLN D CG  1 
ATOM   5704  C CD  . GLN D 2 49  ? -68.950  -19.300 17.257  1.00 55.16  ? 49  GLN D CD  1 
ATOM   5705  O OE1 . GLN D 2 49  ? -69.440  -18.610 18.143  1.00 66.21  ? 49  GLN D OE1 1 
ATOM   5706  N NE2 . GLN D 2 49  ? -68.828  -20.611 17.362  1.00 55.41  ? 49  GLN D NE2 1 
ATOM   5707  N N   . LEU D 2 50  ? -67.462  -18.251 12.559  1.00 50.73  ? 50  LEU D N   1 
ATOM   5708  C CA  . LEU D 2 50  ? -67.025  -19.167 11.510  1.00 49.51  ? 50  LEU D CA  1 
ATOM   5709  C C   . LEU D 2 50  ? -67.294  -20.605 11.917  1.00 55.06  ? 50  LEU D C   1 
ATOM   5710  O O   . LEU D 2 50  ? -66.866  -21.039 12.988  1.00 56.48  ? 50  LEU D O   1 
ATOM   5711  C CB  . LEU D 2 50  ? -65.546  -18.958 11.240  1.00 46.47  ? 50  LEU D CB  1 
ATOM   5712  C CG  . LEU D 2 50  ? -65.292  -17.518 10.835  1.00 51.37  ? 50  LEU D CG  1 
ATOM   5713  C CD1 . LEU D 2 50  ? -63.871  -17.352 10.394  1.00 49.11  ? 50  LEU D CD1 1 
ATOM   5714  C CD2 . LEU D 2 50  ? -66.271  -17.108 9.730   1.00 53.32  ? 50  LEU D CD2 1 
ATOM   5715  N N   . GLU D 2 51  ? -68.014  -21.341 11.065  1.00 56.78  ? 51  GLU D N   1 
ATOM   5716  C CA  . GLU D 2 51  ? -68.447  -22.706 11.369  1.00 58.27  ? 51  GLU D CA  1 
ATOM   5717  C C   . GLU D 2 51  ? -67.434  -23.738 10.869  1.00 59.28  ? 51  GLU D C   1 
ATOM   5718  O O   . GLU D 2 51  ? -67.114  -23.766 9.674   1.00 54.81  ? 51  GLU D O   1 
ATOM   5719  C CB  . GLU D 2 51  ? -69.805  -23.000 10.727  1.00 57.42  ? 51  GLU D CB  1 
ATOM   5720  C CG  . GLU D 2 51  ? -71.042  -22.452 11.421  1.00 58.94  ? 51  GLU D CG  1 
ATOM   5721  C CD  . GLU D 2 51  ? -72.259  -22.488 10.499  1.00 73.10  ? 51  GLU D CD  1 
ATOM   5722  O OE1 . GLU D 2 51  ? -72.139  -23.037 9.377   1.00 80.93  ? 51  GLU D OE1 1 
ATOM   5723  O OE2 . GLU D 2 51  ? -73.332  -21.972 10.879  1.00 70.23  ? 51  GLU D OE2 1 
ATOM   5724  N N   . ASP D 2 52  ? -66.964  -24.612 11.772  1.00 62.86  ? 52  ASP D N   1 
ATOM   5725  C CA  . ASP D 2 52  ? -66.105  -25.721 11.359  1.00 62.15  ? 52  ASP D CA  1 
ATOM   5726  C C   . ASP D 2 52  ? -66.726  -26.450 10.178  1.00 59.83  ? 52  ASP D C   1 
ATOM   5727  O O   . ASP D 2 52  ? -67.931  -26.713 10.157  1.00 55.33  ? 52  ASP D O   1 
ATOM   5728  C CB  . ASP D 2 52  ? -65.875  -26.700 12.514  1.00 63.17  ? 52  ASP D CB  1 
ATOM   5729  C CG  . ASP D 2 52  ? -64.605  -26.390 13.307  1.00 69.34  ? 52  ASP D CG  1 
ATOM   5730  O OD1 . ASP D 2 52  ? -63.679  -25.802 12.719  1.00 67.56  ? 52  ASP D OD1 1 
ATOM   5731  O OD2 . ASP D 2 52  ? -64.521  -26.734 14.511  1.00 71.03  ? 52  ASP D OD2 1 
ATOM   5732  N N   . GLY D 2 53  ? -65.912  -26.727 9.166   1.00 57.73  ? 53  GLY D N   1 
ATOM   5733  C CA  . GLY D 2 53  ? -66.385  -27.365 7.966   1.00 61.46  ? 53  GLY D CA  1 
ATOM   5734  C C   . GLY D 2 53  ? -66.721  -26.422 6.830   1.00 66.97  ? 53  GLY D C   1 
ATOM   5735  O O   . GLY D 2 53  ? -66.803  -26.871 5.677   1.00 70.65  ? 53  GLY D O   1 
ATOM   5736  N N   . ARG D 2 54  ? -66.945  -25.145 7.117   1.00 61.10  ? 54  ARG D N   1 
ATOM   5737  C CA  . ARG D 2 54  ? -67.054  -24.165 6.049   1.00 62.84  ? 54  ARG D CA  1 
ATOM   5738  C C   . ARG D 2 54  ? -65.658  -23.632 5.693   1.00 61.42  ? 54  ARG D C   1 
ATOM   5739  O O   . ARG D 2 54  ? -64.674  -23.865 6.403   1.00 59.76  ? 54  ARG D O   1 
ATOM   5740  C CB  . ARG D 2 54  ? -68.010  -23.043 6.456   1.00 60.47  ? 54  ARG D CB  1 
ATOM   5741  N N   . THR D 2 55  ? -65.586  -22.859 4.605   1.00 61.55  ? 55  THR D N   1 
ATOM   5742  C CA  . THR D 2 55  ? -64.281  -22.301 4.148   1.00 65.66  ? 55  THR D CA  1 
ATOM   5743  C C   . THR D 2 55  ? -64.285  -20.767 4.190   1.00 62.31  ? 55  THR D C   1 
ATOM   5744  O O   . THR D 2 55  ? -65.369  -20.184 4.247   1.00 60.98  ? 55  THR D O   1 
ATOM   5745  C CB  . THR D 2 55  ? -63.891  -22.860 2.774   1.00 62.37  ? 55  THR D CB  1 
ATOM   5746  O OG1 . THR D 2 55  ? -62.547  -22.462 2.531   1.00 69.44  ? 55  THR D OG1 1 
ATOM   5747  C CG2 . THR D 2 55  ? -64.750  -22.369 1.635   1.00 59.62  ? 55  THR D CG2 1 
ATOM   5748  N N   . LEU D 2 56  ? -63.102  -20.148 4.163   1.00 55.49  ? 56  LEU D N   1 
ATOM   5749  C CA  . LEU D 2 56  ? -62.991  -18.665 4.240   1.00 59.68  ? 56  LEU D CA  1 
ATOM   5750  C C   . LEU D 2 56  ? -63.639  -18.025 3.015   1.00 60.31  ? 56  LEU D C   1 
ATOM   5751  O O   . LEU D 2 56  ? -64.156  -16.912 3.149   1.00 59.59  ? 56  LEU D O   1 
ATOM   5752  C CB  . LEU D 2 56  ? -61.517  -18.272 4.327   1.00 48.55  ? 56  LEU D CB  1 
ATOM   5753  C CG  . LEU D 2 56  ? -60.741  -18.859 5.497   1.00 59.01  ? 56  LEU D CG  1 
ATOM   5754  C CD1 . LEU D 2 56  ? -59.259  -18.672 5.264   1.00 60.70  ? 56  LEU D CD1 1 
ATOM   5755  C CD2 . LEU D 2 56  ? -61.154  -18.207 6.803   1.00 59.00  ? 56  LEU D CD2 1 
ATOM   5756  N N   . SER D 2 57  ? -63.595  -18.702 1.872   1.00 61.43  ? 57  SER D N   1 
ATOM   5757  C CA  . SER D 2 57  ? -64.255  -18.197 0.646   1.00 63.80  ? 57  SER D CA  1 
ATOM   5758  C C   . SER D 2 57  ? -65.761  -18.074 0.888   1.00 62.48  ? 57  SER D C   1 
ATOM   5759  O O   . SER D 2 57  ? -66.347  -17.086 0.430   1.00 61.00  ? 57  SER D O   1 
ATOM   5760  C CB  . SER D 2 57  ? -63.939  -19.090 -0.524  1.00 62.21  ? 57  SER D CB  1 
ATOM   5761  O OG  . SER D 2 57  ? -64.968  -20.036 -0.769  1.00 66.15  ? 57  SER D OG  1 
ATOM   5762  N N   . ASP D 2 58  ? -66.350  -19.044 1.579   1.00 57.89  ? 58  ASP D N   1 
ATOM   5763  C CA  . ASP D 2 58  ? -67.809  -19.034 1.834   1.00 59.98  ? 58  ASP D CA  1 
ATOM   5764  C C   . ASP D 2 58  ? -68.190  -17.781 2.626   1.00 58.88  ? 58  ASP D C   1 
ATOM   5765  O O   . ASP D 2 58  ? -69.380  -17.450 2.646   1.00 57.29  ? 58  ASP D O   1 
ATOM   5766  C CB  . ASP D 2 58  ? -68.244  -20.314 2.546   1.00 62.28  ? 58  ASP D CB  1 
ATOM   5767  C CG  . ASP D 2 58  ? -68.106  -21.570 1.708   1.00 64.53  ? 58  ASP D CG  1 
ATOM   5768  O OD1 . ASP D 2 58  ? -68.024  -21.448 0.472   1.00 65.41  ? 58  ASP D OD1 1 
ATOM   5769  O OD2 . ASP D 2 58  ? -68.075  -22.661 2.304   1.00 64.72  ? 58  ASP D OD2 1 
ATOM   5770  N N   . TYR D 2 59  ? -67.219  -17.119 3.251   1.00 58.53  ? 59  TYR D N   1 
ATOM   5771  C CA  . TYR D 2 59  ? -67.545  -15.955 4.054   1.00 52.38  ? 59  TYR D CA  1 
ATOM   5772  C C   . TYR D 2 59  ? -67.012  -14.665 3.456   1.00 55.07  ? 59  TYR D C   1 
ATOM   5773  O O   . TYR D 2 59  ? -67.079  -13.628 4.112   1.00 61.16  ? 59  TYR D O   1 
ATOM   5774  C CB  . TYR D 2 59  ? -66.988  -16.111 5.471   1.00 61.00  ? 59  TYR D CB  1 
ATOM   5775  C CG  . TYR D 2 59  ? -67.622  -17.182 6.354   1.00 59.64  ? 59  TYR D CG  1 
ATOM   5776  C CD1 . TYR D 2 59  ? -68.761  -16.915 7.102   1.00 56.71  ? 59  TYR D CD1 1 
ATOM   5777  C CD2 . TYR D 2 59  ? -67.046  -18.440 6.469   1.00 55.83  ? 59  TYR D CD2 1 
ATOM   5778  C CE1 . TYR D 2 59  ? -69.325  -17.877 7.911   1.00 59.05  ? 59  TYR D CE1 1 
ATOM   5779  C CE2 . TYR D 2 59  ? -67.600  -19.410 7.276   1.00 58.54  ? 59  TYR D CE2 1 
ATOM   5780  C CZ  . TYR D 2 59  ? -68.734  -19.127 7.999   1.00 62.67  ? 59  TYR D CZ  1 
ATOM   5781  O OH  . TYR D 2 59  ? -69.269  -20.100 8.810   1.00 59.63  ? 59  TYR D OH  1 
ATOM   5782  N N   . ASN D 2 60  ? -66.457  -14.698 2.251   1.00 55.82  ? 60  ASN D N   1 
ATOM   5783  C CA  . ASN D 2 60  ? -65.882  -13.497 1.636   1.00 58.24  ? 60  ASN D CA  1 
ATOM   5784  C C   . ASN D 2 60  ? -64.738  -12.924 2.458   1.00 53.85  ? 60  ASN D C   1 
ATOM   5785  O O   . ASN D 2 60  ? -64.518  -11.712 2.470   1.00 50.47  ? 60  ASN D O   1 
ATOM   5786  C CB  . ASN D 2 60  ? -66.931  -12.409 1.410   1.00 56.09  ? 60  ASN D CB  1 
ATOM   5787  C CG  . ASN D 2 60  ? -67.667  -12.580 0.127   1.00 57.56  ? 60  ASN D CG  1 
ATOM   5788  O OD1 . ASN D 2 60  ? -67.107  -13.057 -0.854  1.00 66.77  ? 60  ASN D OD1 1 
ATOM   5789  N ND2 . ASN D 2 60  ? -68.940  -12.204 0.120   1.00 64.81  ? 60  ASN D ND2 1 
ATOM   5790  N N   . ILE D 2 61  ? -64.012  -13.783 3.151   1.00 54.97  ? 61  ILE D N   1 
ATOM   5791  C CA  . ILE D 2 61  ? -62.789  -13.368 3.830   1.00 56.16  ? 61  ILE D CA  1 
ATOM   5792  C C   . ILE D 2 61  ? -61.667  -13.263 2.805   1.00 48.75  ? 61  ILE D C   1 
ATOM   5793  O O   . ILE D 2 61  ? -61.400  -14.205 2.058   1.00 48.44  ? 61  ILE D O   1 
ATOM   5794  C CB  . ILE D 2 61  ? -62.436  -14.351 4.956   1.00 52.08  ? 61  ILE D CB  1 
ATOM   5795  C CG1 . ILE D 2 61  ? -63.437  -14.177 6.099   1.00 48.15  ? 61  ILE D CG1 1 
ATOM   5796  C CG2 . ILE D 2 61  ? -60.966  -14.186 5.394   1.00 38.89  ? 61  ILE D CG2 1 
ATOM   5797  C CD1 . ILE D 2 61  ? -63.762  -15.469 6.821   1.00 53.86  ? 61  ILE D CD1 1 
ATOM   5798  N N   . GLN D 2 62  ? -61.010  -12.115 2.765   1.00 44.09  ? 62  GLN D N   1 
ATOM   5799  C CA  . GLN D 2 62  ? -60.000  -11.852 1.763   1.00 48.32  ? 62  GLN D CA  1 
ATOM   5800  C C   . GLN D 2 62  ? -58.815  -11.220 2.464   1.00 46.31  ? 62  GLN D C   1 
ATOM   5801  O O   . GLN D 2 62  ? -58.819  -11.076 3.687   1.00 44.90  ? 62  GLN D O   1 
ATOM   5802  C CB  . GLN D 2 62  ? -60.552  -10.935 0.674   1.00 51.94  ? 62  GLN D CB  1 
ATOM   5803  C CG  . GLN D 2 62  ? -61.003  -9.619  1.238   1.00 49.10  ? 62  GLN D CG  1 
ATOM   5804  C CD  . GLN D 2 62  ? -61.709  -8.781  0.228   1.00 53.85  ? 62  GLN D CD  1 
ATOM   5805  O OE1 . GLN D 2 62  ? -61.249  -8.635  -0.911  1.00 54.34  ? 62  GLN D OE1 1 
ATOM   5806  N NE2 . GLN D 2 62  ? -62.844  -8.209  0.631   1.00 55.69  ? 62  GLN D NE2 1 
ATOM   5807  N N   . LYS D 2 63  ? -57.803  -10.829 1.681   1.00 46.65  ? 63  LYS D N   1 
ATOM   5808  C CA  . LYS D 2 63  ? -56.691  -10.060 2.227   1.00 48.15  ? 63  LYS D CA  1 
ATOM   5809  C C   . LYS D 2 63  ? -57.215  -8.935  3.109   1.00 50.27  ? 63  LYS D C   1 
ATOM   5810  O O   . LYS D 2 63  ? -58.237  -8.312  2.811   1.00 52.69  ? 63  LYS D O   1 
ATOM   5811  C CB  . LYS D 2 63  ? -55.823  -9.478  1.108   1.00 46.05  ? 63  LYS D CB  1 
ATOM   5812  C CG  . LYS D 2 63  ? -54.341  -9.375  1.470   1.00 57.07  ? 63  LYS D CG  1 
ATOM   5813  C CD  . LYS D 2 63  ? -53.595  -8.230  0.770   1.00 51.71  ? 63  LYS D CD  1 
ATOM   5814  C CE  . LYS D 2 63  ? -52.279  -7.880  1.485   1.00 53.44  ? 63  LYS D CE  1 
ATOM   5815  N N   . GLU D 2 64  ? -56.540  -8.726  4.232   1.00 45.16  ? 64  GLU D N   1 
ATOM   5816  C CA  . GLU D 2 64  ? -56.776  -7.639  5.173   1.00 46.21  ? 64  GLU D CA  1 
ATOM   5817  C C   . GLU D 2 64  ? -58.093  -7.736  5.945   1.00 51.20  ? 64  GLU D C   1 
ATOM   5818  O O   . GLU D 2 64  ? -58.431  -6.789  6.682   1.00 50.89  ? 64  GLU D O   1 
ATOM   5819  C CB  . GLU D 2 64  ? -56.675  -6.287  4.467   1.00 47.16  ? 64  GLU D CB  1 
ATOM   5820  C CG  . GLU D 2 64  ? -55.367  -6.150  3.725   1.00 57.63  ? 64  GLU D CG  1 
ATOM   5821  C CD  . GLU D 2 64  ? -55.185  -4.823  3.005   1.00 59.08  ? 64  GLU D CD  1 
ATOM   5822  O OE1 . GLU D 2 64  ? -55.916  -3.852  3.287   1.00 66.74  ? 64  GLU D OE1 1 
ATOM   5823  O OE2 . GLU D 2 64  ? -54.264  -4.737  2.179   1.00 62.07  ? 64  GLU D OE2 1 
ATOM   5824  N N   . SER D 2 65  ? -58.849  -8.829  5.826   1.00 43.49  ? 65  SER D N   1 
ATOM   5825  C CA  . SER D 2 65  ? -59.937  -9.019  6.773   1.00 39.07  ? 65  SER D CA  1 
ATOM   5826  C C   . SER D 2 65  ? -59.365  -9.252  8.159   1.00 43.61  ? 65  SER D C   1 
ATOM   5827  O O   . SER D 2 65  ? -58.276  -9.808  8.317   1.00 45.56  ? 65  SER D O   1 
ATOM   5828  C CB  . SER D 2 65  ? -60.825  -10.204 6.417   1.00 40.27  ? 65  SER D CB  1 
ATOM   5829  O OG  . SER D 2 65  ? -61.019  -10.350 5.032   1.00 51.25  ? 65  SER D OG  1 
ATOM   5830  N N   . THR D 2 66  ? -60.109  -8.795  9.169   1.00 49.47  ? 66  THR D N   1 
ATOM   5831  C CA  . THR D 2 66  ? -59.814  -9.010  10.584  1.00 43.55  ? 66  THR D CA  1 
ATOM   5832  C C   . THR D 2 66  ? -60.793  -10.023 11.149  1.00 46.32  ? 66  THR D C   1 
ATOM   5833  O O   . THR D 2 66  ? -62.006  -9.798  11.128  1.00 48.69  ? 66  THR D O   1 
ATOM   5834  C CB  . THR D 2 66  ? -59.950  -7.732  11.402  1.00 43.19  ? 66  THR D CB  1 
ATOM   5835  O OG1 . THR D 2 66  ? -59.026  -6.745  10.944  1.00 50.35  ? 66  THR D OG1 1 
ATOM   5836  C CG2 . THR D 2 66  ? -59.680  -8.051  12.847  1.00 43.66  ? 66  THR D CG2 1 
ATOM   5837  N N   . LEU D 2 67  ? -60.277  -11.116 11.673  1.00 49.77  ? 67  LEU D N   1 
ATOM   5838  C CA  . LEU D 2 67  ? -61.109  -12.021 12.437  1.00 47.68  ? 67  LEU D CA  1 
ATOM   5839  C C   . LEU D 2 67  ? -61.062  -11.620 13.908  1.00 45.41  ? 67  LEU D C   1 
ATOM   5840  O O   . LEU D 2 67  ? -60.087  -11.028 14.384  1.00 46.47  ? 67  LEU D O   1 
ATOM   5841  C CB  . LEU D 2 67  ? -60.640  -13.463 12.258  1.00 49.45  ? 67  LEU D CB  1 
ATOM   5842  C CG  . LEU D 2 67  ? -61.263  -14.279 11.136  1.00 46.19  ? 67  LEU D CG  1 
ATOM   5843  C CD1 . LEU D 2 67  ? -61.416  -13.437 9.895   1.00 44.74  ? 67  LEU D CD1 1 
ATOM   5844  C CD2 . LEU D 2 67  ? -60.363  -15.474 10.885  1.00 42.31  ? 67  LEU D CD2 1 
ATOM   5845  N N   . HIS D 2 68  ? -62.122  -11.943 14.629  1.00 45.06  ? 68  HIS D N   1 
ATOM   5846  C CA  . HIS D 2 68  ? -62.170  -11.677 16.054  1.00 46.39  ? 68  HIS D CA  1 
ATOM   5847  C C   . HIS D 2 68  ? -62.192  -12.996 16.815  1.00 53.21  ? 68  HIS D C   1 
ATOM   5848  O O   . HIS D 2 68  ? -63.160  -13.765 16.730  1.00 50.41  ? 68  HIS D O   1 
ATOM   5849  C CB  . HIS D 2 68  ? -63.341  -10.768 16.370  1.00 43.37  ? 68  HIS D CB  1 
ATOM   5850  C CG  . HIS D 2 68  ? -63.100  -9.369  15.900  1.00 52.46  ? 68  HIS D CG  1 
ATOM   5851  N ND1 . HIS D 2 68  ? -63.576  -8.897  14.692  1.00 45.25  ? 68  HIS D ND1 1 
ATOM   5852  C CD2 . HIS D 2 68  ? -62.351  -8.370  16.429  1.00 45.68  ? 68  HIS D CD2 1 
ATOM   5853  C CE1 . HIS D 2 68  ? -63.171  -7.652  14.523  1.00 41.22  ? 68  HIS D CE1 1 
ATOM   5854  N NE2 . HIS D 2 68  ? -62.410  -7.315  15.552  1.00 41.91  ? 68  HIS D NE2 1 
ATOM   5855  N N   . LEU D 2 69  ? -61.092  -13.248 17.532  1.00 52.41  ? 69  LEU D N   1 
ATOM   5856  C CA  . LEU D 2 69  ? -60.885  -14.448 18.329  1.00 50.31  ? 69  LEU D CA  1 
ATOM   5857  C C   . LEU D 2 69  ? -61.498  -14.294 19.712  1.00 54.82  ? 69  LEU D C   1 
ATOM   5858  O O   . LEU D 2 69  ? -61.267  -13.295 20.403  1.00 56.52  ? 69  LEU D O   1 
ATOM   5859  C CB  . LEU D 2 69  ? -59.395  -14.735 18.470  1.00 53.86  ? 69  LEU D CB  1 
ATOM   5860  C CG  . LEU D 2 69  ? -59.069  -15.798 19.500  1.00 50.32  ? 69  LEU D CG  1 
ATOM   5861  C CD1 . LEU D 2 69  ? -59.736  -17.111 19.100  1.00 54.59  ? 69  LEU D CD1 1 
ATOM   5862  C CD2 . LEU D 2 69  ? -57.575  -15.946 19.605  1.00 52.61  ? 69  LEU D CD2 1 
ATOM   5863  N N   . VAL D 2 70  ? -62.255  -15.302 20.122  1.00 57.13  ? 70  VAL D N   1 
ATOM   5864  C CA  . VAL D 2 70  ? -62.996  -15.248 21.372  1.00 59.71  ? 70  VAL D CA  1 
ATOM   5865  C C   . VAL D 2 70  ? -63.057  -16.658 21.962  1.00 62.32  ? 70  VAL D C   1 
ATOM   5866  O O   . VAL D 2 70  ? -63.119  -17.651 21.225  1.00 58.76  ? 70  VAL D O   1 
ATOM   5867  C CB  . VAL D 2 70  ? -64.386  -14.626 21.126  1.00 54.79  ? 70  VAL D CB  1 
ATOM   5868  C CG1 . VAL D 2 70  ? -65.386  -15.108 22.112  1.00 60.12  ? 70  VAL D CG1 1 
ATOM   5869  C CG2 . VAL D 2 70  ? -64.291  -13.123 21.200  1.00 51.07  ? 70  VAL D CG2 1 
ATOM   5870  N N   . LEU D 2 71  ? -62.991  -16.734 23.303  1.00 55.68  ? 71  LEU D N   1 
ATOM   5871  C CA  . LEU D 2 71  ? -63.036  -17.951 24.105  1.00 57.85  ? 71  LEU D CA  1 
ATOM   5872  C C   . LEU D 2 71  ? -64.466  -18.223 24.579  1.00 58.74  ? 71  LEU D C   1 
ATOM   5873  O O   . LEU D 2 71  ? -65.430  -17.678 24.033  1.00 61.97  ? 71  LEU D O   1 
ATOM   5874  C CB  . LEU D 2 71  ? -62.062  -17.833 25.281  1.00 53.51  ? 71  LEU D CB  1 
ATOM   5875  C CG  . LEU D 2 71  ? -60.603  -17.976 24.900  1.00 47.80  ? 71  LEU D CG  1 
ATOM   5876  C CD1 . LEU D 2 71  ? -59.787  -17.991 26.158  1.00 52.13  ? 71  LEU D CD1 1 
ATOM   5877  C CD2 . LEU D 2 71  ? -60.381  -19.216 24.069  1.00 42.15  ? 71  LEU D CD2 1 
ATOM   5878  N N   . ARG D 2 72  ? -64.619  -19.084 25.580  1.00 54.46  ? 72  ARG D N   1 
ATOM   5879  C CA  . ARG D 2 72  ? -65.943  -19.422 26.083  1.00 58.50  ? 72  ARG D CA  1 
ATOM   5880  C C   . ARG D 2 72  ? -66.062  -19.189 27.589  1.00 61.64  ? 72  ARG D C   1 
ATOM   5881  O O   . ARG D 2 72  ? -65.119  -19.436 28.351  1.00 64.11  ? 72  ARG D O   1 
ATOM   5882  C CB  . ARG D 2 72  ? -66.287  -20.867 25.766  1.00 51.66  ? 72  ARG D CB  1 
ATOM   5883  C CG  . ARG D 2 72  ? -66.687  -21.092 24.356  1.00 51.11  ? 72  ARG D CG  1 
ATOM   5884  C CD  . ARG D 2 72  ? -67.312  -22.448 24.212  1.00 49.86  ? 72  ARG D CD  1 
ATOM   5885  N NE  . ARG D 2 72  ? -67.436  -22.867 22.822  1.00 47.76  ? 72  ARG D NE  1 
ATOM   5886  C CZ  . ARG D 2 72  ? -66.422  -23.306 22.095  1.00 43.93  ? 72  ARG D CZ  1 
ATOM   5887  N NH1 . ARG D 2 72  ? -65.220  -23.369 22.629  1.00 51.67  ? 72  ARG D NH1 1 
ATOM   5888  N NH2 . ARG D 2 72  ? -66.611  -23.681 20.844  1.00 42.43  ? 72  ARG D NH2 1 
ATOM   5889  N N   . LEU D 2 73  ? -67.234  -18.716 28.011  1.00 54.64  ? 73  LEU D N   1 
ATOM   5890  C CA  . LEU D 2 73  ? -67.652  -18.714 29.409  1.00 57.14  ? 73  LEU D CA  1 
ATOM   5891  C C   . LEU D 2 73  ? -68.944  -19.528 29.499  1.00 60.34  ? 73  LEU D C   1 
ATOM   5892  O O   . LEU D 2 73  ? -70.028  -18.987 29.265  1.00 57.70  ? 73  LEU D O   1 
ATOM   5893  C CB  . LEU D 2 73  ? -67.855  -17.309 29.906  1.00 56.44  ? 73  LEU D CB  1 
ATOM   5894  C CG  . LEU D 2 73  ? -66.734  -16.724 30.762  1.00 57.00  ? 73  LEU D CG  1 
ATOM   5895  C CD1 . LEU D 2 73  ? -65.384  -16.997 30.130  1.00 62.37  ? 73  LEU D CD1 1 
ATOM   5896  C CD2 . LEU D 2 73  ? -66.961  -15.221 30.997  1.00 51.79  ? 73  LEU D CD2 1 
ATOM   5897  N N   . ARG D 2 74  ? -68.801  -20.797 29.876  1.00 66.03  ? 74  ARG D N   1 
ATOM   5898  C CA  . ARG D 2 74  ? -69.958  -21.728 29.896  1.00 68.46  ? 74  ARG D CA  1 
ATOM   5899  C C   . ARG D 2 74  ? -70.812  -21.550 31.152  1.00 62.04  ? 74  ARG D C   1 
ATOM   5900  O O   . ARG D 2 74  ? -70.277  -21.125 32.177  1.00 61.82  ? 74  ARG D O   1 
ATOM   5901  C CB  . ARG D 2 74  ? -69.433  -23.155 29.717  1.00 64.99  ? 74  ARG D CB  1 
ATOM   5902  C CG  . ARG D 2 74  ? -68.493  -23.314 28.532  1.00 61.23  ? 74  ARG D CG  1 
ATOM   5903  C CD  . ARG D 2 74  ? -68.294  -24.762 28.136  1.00 56.03  ? 74  ARG D CD  1 
ATOM   5904  N NE  . ARG D 2 74  ? -69.058  -25.104 26.946  1.00 51.94  ? 74  ARG D NE  1 
ATOM   5905  C CZ  . ARG D 2 74  ? -68.549  -25.655 25.854  1.00 51.83  ? 74  ARG D CZ  1 
ATOM   5906  N NH1 . ARG D 2 74  ? -67.261  -25.933 25.788  1.00 45.99  ? 74  ARG D NH1 1 
ATOM   5907  N NH2 . ARG D 2 74  ? -69.328  -25.929 24.826  1.00 48.42  ? 74  ARG D NH2 1 
ATOM   5908  N N   . GLY D 2 75  ? -72.097  -21.889 31.056  1.00 60.16  ? 75  GLY D N   1 
ATOM   5909  C CA  . GLY D 2 75  ? -73.013  -21.685 32.167  1.00 64.17  ? 75  GLY D CA  1 
ATOM   5910  C C   . GLY D 2 75  ? -74.311  -22.434 31.986  1.00 61.34  ? 75  GLY D C   1 
ATOM   5911  O O   . GLY D 2 75  ? -74.679  -22.763 30.857  1.00 59.32  ? 75  GLY D O   1 
ATOM   5912  N N   . GLY E 1 5   ? -48.823  33.930  29.409  1.00 78.88  ? 212 GLY E N   1 
ATOM   5913  C CA  . GLY E 1 5   ? -48.084  33.505  30.587  1.00 75.19  ? 212 GLY E CA  1 
ATOM   5914  C C   . GLY E 1 5   ? -48.873  32.588  31.512  1.00 78.00  ? 212 GLY E C   1 
ATOM   5915  O O   . GLY E 1 5   ? -48.433  32.272  32.626  1.00 69.68  ? 212 GLY E O   1 
ATOM   5916  N N   . TYR E 1 6   ? -50.041  32.171  31.027  1.00 75.11  ? 213 TYR E N   1 
ATOM   5917  C CA  . TYR E 1 6   ? -50.939  31.323  31.841  1.00 67.80  ? 213 TYR E CA  1 
ATOM   5918  C C   . TYR E 1 6   ? -50.961  29.894  31.306  1.00 71.85  ? 213 TYR E C   1 
ATOM   5919  O O   . TYR E 1 6   ? -50.846  29.704  30.087  1.00 75.35  ? 213 TYR E O   1 
ATOM   5920  C CB  . TYR E 1 6   ? -52.351  31.906  31.839  1.00 66.58  ? 213 TYR E CB  1 
ATOM   5921  C CG  . TYR E 1 6   ? -52.472  33.360  32.213  1.00 62.81  ? 213 TYR E CG  1 
ATOM   5922  C CD1 . TYR E 1 6   ? -52.044  33.823  33.445  1.00 64.21  ? 213 TYR E CD1 1 
ATOM   5923  C CD2 . TYR E 1 6   ? -53.043  34.269  31.341  1.00 58.33  ? 213 TYR E CD2 1 
ATOM   5924  C CE1 . TYR E 1 6   ? -52.162  35.157  33.794  1.00 62.74  ? 213 TYR E CE1 1 
ATOM   5925  C CE2 . TYR E 1 6   ? -53.166  35.606  31.672  1.00 60.51  ? 213 TYR E CE2 1 
ATOM   5926  C CZ  . TYR E 1 6   ? -52.726  36.052  32.904  1.00 68.28  ? 213 TYR E CZ  1 
ATOM   5927  O OH  . TYR E 1 6   ? -52.850  37.368  33.237  1.00 62.46  ? 213 TYR E OH  1 
ATOM   5928  N N   . VAL E 1 7   ? -51.122  28.925  32.198  1.00 70.15  ? 214 VAL E N   1 
ATOM   5929  C CA  . VAL E 1 7   ? -51.182  27.506  31.855  1.00 71.52  ? 214 VAL E CA  1 
ATOM   5930  C C   . VAL E 1 7   ? -52.638  27.049  31.737  1.00 68.21  ? 214 VAL E C   1 
ATOM   5931  O O   . VAL E 1 7   ? -53.568  27.740  32.145  1.00 68.17  ? 214 VAL E O   1 
ATOM   5932  C CB  . VAL E 1 7   ? -50.416  26.697  32.921  1.00 75.22  ? 214 VAL E CB  1 
ATOM   5933  C CG1 . VAL E 1 7   ? -51.098  26.859  34.263  1.00 75.46  ? 214 VAL E CG1 1 
ATOM   5934  C CG2 . VAL E 1 7   ? -50.277  25.236  32.542  1.00 76.88  ? 214 VAL E CG2 1 
ATOM   5935  N N   . GLY E 1 8   ? -52.849  25.879  31.135  1.00 67.62  ? 215 GLY E N   1 
ATOM   5936  C CA  . GLY E 1 8   ? -54.150  25.258  31.064  1.00 65.79  ? 215 GLY E CA  1 
ATOM   5937  C C   . GLY E 1 8   ? -54.275  24.071  32.006  1.00 71.07  ? 215 GLY E C   1 
ATOM   5938  O O   . GLY E 1 8   ? -53.463  23.862  32.911  1.00 71.62  ? 215 GLY E O   1 
ATOM   5939  N N   . LEU E 1 9   ? -55.319  23.274  31.770  1.00 67.22  ? 216 LEU E N   1 
ATOM   5940  C CA  . LEU E 1 9   ? -55.593  22.096  32.582  1.00 65.74  ? 216 LEU E CA  1 
ATOM   5941  C C   . LEU E 1 9   ? -55.910  20.919  31.677  1.00 65.78  ? 216 LEU E C   1 
ATOM   5942  O O   . LEU E 1 9   ? -56.430  21.091  30.573  1.00 66.73  ? 216 LEU E O   1 
ATOM   5943  C CB  . LEU E 1 9   ? -56.764  22.315  33.546  1.00 62.85  ? 216 LEU E CB  1 
ATOM   5944  C CG  . LEU E 1 9   ? -56.569  23.321  34.690  1.00 67.09  ? 216 LEU E CG  1 
ATOM   5945  C CD1 . LEU E 1 9   ? -57.781  24.221  34.846  1.00 59.35  ? 216 LEU E CD1 1 
ATOM   5946  C CD2 . LEU E 1 9   ? -56.256  22.633  36.011  1.00 64.03  ? 216 LEU E CD2 1 
ATOM   5947  N N   . LYS E 1 10  ? -55.590  19.719  32.154  1.00 65.02  ? 217 LYS E N   1 
ATOM   5948  C CA  . LYS E 1 10  ? -55.817  18.516  31.364  1.00 59.16  ? 217 LYS E CA  1 
ATOM   5949  C C   . LYS E 1 10  ? -57.291  18.133  31.372  1.00 58.61  ? 217 LYS E C   1 
ATOM   5950  O O   . LYS E 1 10  ? -58.073  18.554  32.226  1.00 64.44  ? 217 LYS E O   1 
ATOM   5951  C CB  . LYS E 1 10  ? -54.980  17.357  31.894  1.00 58.34  ? 217 LYS E CB  1 
ATOM   5952  C CG  . LYS E 1 10  ? -53.514  17.704  32.069  1.00 67.51  ? 217 LYS E CG  1 
ATOM   5953  C CD  . LYS E 1 10  ? -52.807  16.635  32.869  1.00 63.83  ? 217 LYS E CD  1 
ATOM   5954  C CE  . LYS E 1 10  ? -51.318  16.820  32.846  1.00 66.47  ? 217 LYS E CE  1 
ATOM   5955  N NZ  . LYS E 1 10  ? -50.694  15.748  33.652  1.00 73.07  ? 217 LYS E NZ  1 
ATOM   5956  N N   . ASN E 1 11  ? -57.668  17.327  30.405  1.00 56.82  ? 218 ASN E N   1 
ATOM   5957  C CA  . ASN E 1 11  ? -59.012  16.786  30.342  1.00 58.49  ? 218 ASN E CA  1 
ATOM   5958  C C   . ASN E 1 11  ? -58.936  15.312  30.686  1.00 63.21  ? 218 ASN E C   1 
ATOM   5959  O O   . ASN E 1 11  ? -58.505  14.512  29.854  1.00 67.30  ? 218 ASN E O   1 
ATOM   5960  C CB  . ASN E 1 11  ? -59.638  16.969  28.968  1.00 58.83  ? 218 ASN E CB  1 
ATOM   5961  C CG  . ASN E 1 11  ? -61.030  16.380  28.903  1.00 66.54  ? 218 ASN E CG  1 
ATOM   5962  O OD1 . ASN E 1 11  ? -61.612  16.051  29.945  1.00 69.17  ? 218 ASN E OD1 1 
ATOM   5963  N ND2 . ASN E 1 11  ? -61.592  16.275  27.696  1.00 57.49  ? 218 ASN E ND2 1 
ATOM   5964  N N   . GLN E 1 12  ? -59.381  14.953  31.896  1.00 61.76  ? 219 GLN E N   1 
ATOM   5965  C CA  . GLN E 1 12  ? -59.489  13.546  32.265  1.00 61.29  ? 219 GLN E CA  1 
ATOM   5966  C C   . GLN E 1 12  ? -60.358  12.760  31.286  1.00 61.90  ? 219 GLN E C   1 
ATOM   5967  O O   . GLN E 1 12  ? -60.262  11.528  31.237  1.00 61.67  ? 219 GLN E O   1 
ATOM   5968  C CB  . GLN E 1 12  ? -60.065  13.401  33.680  1.00 61.68  ? 219 GLN E CB  1 
ATOM   5969  C CG  . GLN E 1 12  ? -59.088  13.681  34.796  1.00 61.99  ? 219 GLN E CG  1 
ATOM   5970  C CD  . GLN E 1 12  ? -59.649  13.350  36.172  1.00 70.34  ? 219 GLN E CD  1 
ATOM   5971  O OE1 . GLN E 1 12  ? -59.984  12.193  36.465  1.00 69.86  ? 219 GLN E OE1 1 
ATOM   5972  N NE2 . GLN E 1 12  ? -59.741  14.368  37.035  1.00 64.48  ? 219 GLN E NE2 1 
ATOM   5973  N N   . GLY E 1 13  ? -61.194  13.438  30.503  1.00 59.67  ? 220 GLY E N   1 
ATOM   5974  C CA  . GLY E 1 13  ? -62.069  12.750  29.578  1.00 62.38  ? 220 GLY E CA  1 
ATOM   5975  C C   . GLY E 1 13  ? -63.316  13.549  29.275  1.00 63.41  ? 220 GLY E C   1 
ATOM   5976  O O   . GLY E 1 13  ? -63.688  13.715  28.105  1.00 66.21  ? 220 GLY E O   1 
ATOM   5977  N N   . ALA E 1 14  ? -63.968  14.060  30.331  1.00 60.10  ? 221 ALA E N   1 
ATOM   5978  C CA  . ALA E 1 14  ? -65.142  14.901  30.140  1.00 54.18  ? 221 ALA E CA  1 
ATOM   5979  C C   . ALA E 1 14  ? -65.169  16.127  31.048  1.00 57.00  ? 221 ALA E C   1 
ATOM   5980  O O   . ALA E 1 14  ? -66.226  16.748  31.185  1.00 59.71  ? 221 ALA E O   1 
ATOM   5981  C CB  . ALA E 1 14  ? -66.412  14.097  30.361  1.00 53.16  ? 221 ALA E CB  1 
ATOM   5982  N N   . THR E 1 15  ? -64.026  16.464  31.645  1.00 55.12  ? 222 THR E N   1 
ATOM   5983  C CA  . THR E 1 15  ? -63.958  17.533  32.675  1.00 57.92  ? 222 THR E CA  1 
ATOM   5984  C C   . THR E 1 15  ? -63.871  18.939  32.084  1.00 61.33  ? 222 THR E C   1 
ATOM   5985  O O   . THR E 1 15  ? -63.331  19.809  32.772  1.00 60.70  ? 222 THR E O   1 
ATOM   5986  C CB  . THR E 1 15  ? -62.793  17.227  33.619  1.00 64.03  ? 222 THR E CB  1 
ATOM   5987  O OG1 . THR E 1 15  ? -61.581  17.187  32.867  1.00 69.43  ? 222 THR E OG1 1 
ATOM   5988  C CG2 . THR E 1 15  ? -62.977  15.914  34.348  1.00 60.02  ? 222 THR E CG2 1 
ATOM   5989  N N   . CYS E 1 16  ? -64.430  19.160  30.901  1.00 58.59  ? 223 CYS E N   1 
ATOM   5990  C CA  . CYS E 1 16  ? -64.478  20.514  30.299  1.00 53.46  ? 223 CYS E CA  1 
ATOM   5991  C C   . CYS E 1 16  ? -65.107  21.482  31.300  1.00 60.95  ? 223 CYS E C   1 
ATOM   5992  O O   . CYS E 1 16  ? -64.591  22.599  31.431  1.00 51.63  ? 223 CYS E O   1 
ATOM   5993  C CB  . CYS E 1 16  ? -65.318  20.474  29.031  1.00 48.29  ? 223 CYS E CB  1 
ATOM   5994  S SG  . CYS E 1 16  ? -65.385  18.852  28.232  1.00 68.07  ? 223 CYS E SG  1 
ATOM   5995  N N   . TYR E 1 17  ? -66.176  21.061  31.976  1.00 62.81  ? 224 TYR E N   1 
ATOM   5996  C CA  . TYR E 1 17  ? -66.899  21.892  32.975  1.00 60.53  ? 224 TYR E CA  1 
ATOM   5997  C C   . TYR E 1 17  ? -65.952  22.307  34.094  1.00 55.40  ? 224 TYR E C   1 
ATOM   5998  O O   . TYR E 1 17  ? -65.839  23.505  34.351  1.00 53.86  ? 224 TYR E O   1 
ATOM   5999  C CB  . TYR E 1 17  ? -68.118  21.125  33.510  1.00 58.12  ? 224 TYR E CB  1 
ATOM   6000  C CG  . TYR E 1 17  ? -67.844  19.799  34.175  1.00 55.21  ? 224 TYR E CG  1 
ATOM   6001  C CD1 . TYR E 1 17  ? -67.611  18.661  33.426  1.00 57.53  ? 224 TYR E CD1 1 
ATOM   6002  C CD2 . TYR E 1 17  ? -67.823  19.678  35.555  1.00 57.08  ? 224 TYR E CD2 1 
ATOM   6003  C CE1 . TYR E 1 17  ? -67.347  17.445  34.028  1.00 59.35  ? 224 TYR E CE1 1 
ATOM   6004  C CE2 . TYR E 1 17  ? -67.549  18.471  36.174  1.00 53.79  ? 224 TYR E CE2 1 
ATOM   6005  C CZ  . TYR E 1 17  ? -67.312  17.350  35.403  1.00 55.40  ? 224 TYR E CZ  1 
ATOM   6006  O OH  . TYR E 1 17  ? -67.060  16.141  35.974  1.00 62.40  ? 224 TYR E OH  1 
ATOM   6007  N N   . MET E 1 18  ? -65.310  21.331  34.729  1.00 54.28  ? 225 MET E N   1 
ATOM   6008  C CA  . MET E 1 18  ? -64.419  21.622  35.841  1.00 52.18  ? 225 MET E CA  1 
ATOM   6009  C C   . MET E 1 18  ? -63.336  22.611  35.443  1.00 52.97  ? 225 MET E C   1 
ATOM   6010  O O   . MET E 1 18  ? -63.037  23.556  36.183  1.00 54.43  ? 225 MET E O   1 
ATOM   6011  C CB  . MET E 1 18  ? -63.786  20.332  36.326  1.00 56.09  ? 225 MET E CB  1 
ATOM   6012  C CG  . MET E 1 18  ? -63.273  20.394  37.716  1.00 60.12  ? 225 MET E CG  1 
ATOM   6013  S SD  . MET E 1 18  ? -63.045  18.725  38.305  1.00 53.50  ? 225 MET E SD  1 
ATOM   6014  C CE  . MET E 1 18  ? -61.856  18.209  37.079  1.00 65.60  ? 225 MET E CE  1 
ATOM   6015  N N   . ASN E 1 19  ? -62.723  22.407  34.285  1.00 52.43  ? 226 ASN E N   1 
ATOM   6016  C CA  . ASN E 1 19  ? -61.580  23.239  33.936  1.00 55.17  ? 226 ASN E CA  1 
ATOM   6017  C C   . ASN E 1 19  ? -61.995  24.696  33.734  1.00 57.84  ? 226 ASN E C   1 
ATOM   6018  O O   . ASN E 1 19  ? -61.329  25.609  34.236  1.00 57.71  ? 226 ASN E O   1 
ATOM   6019  C CB  . ASN E 1 19  ? -60.882  22.667  32.711  1.00 54.20  ? 226 ASN E CB  1 
ATOM   6020  C CG  . ASN E 1 19  ? -60.294  21.297  32.978  1.00 57.86  ? 226 ASN E CG  1 
ATOM   6021  O OD1 . ASN E 1 19  ? -60.170  20.887  34.125  1.00 55.01  ? 226 ASN E OD1 1 
ATOM   6022  N ND2 . ASN E 1 19  ? -59.936  20.579  31.919  1.00 59.05  ? 226 ASN E ND2 1 
ATOM   6023  N N   . SER E 1 20  ? -63.108  24.935  33.040  1.00 56.49  ? 227 SER E N   1 
ATOM   6024  C CA  . SER E 1 20  ? -63.592  26.300  32.864  1.00 49.50  ? 227 SER E CA  1 
ATOM   6025  C C   . SER E 1 20  ? -63.867  26.954  34.216  1.00 55.38  ? 227 SER E C   1 
ATOM   6026  O O   . SER E 1 20  ? -63.549  28.130  34.433  1.00 56.60  ? 227 SER E O   1 
ATOM   6027  C CB  . SER E 1 20  ? -64.852  26.281  32.019  1.00 46.75  ? 227 SER E CB  1 
ATOM   6028  O OG  . SER E 1 20  ? -64.571  25.674  30.772  1.00 57.22  ? 227 SER E OG  1 
ATOM   6029  N N   . LEU E 1 21  ? -64.449  26.210  35.154  1.00 55.02  ? 228 LEU E N   1 
ATOM   6030  C CA  . LEU E 1 21  ? -64.799  26.767  36.488  1.00 53.41  ? 228 LEU E CA  1 
ATOM   6031  C C   . LEU E 1 21  ? -63.528  27.007  37.294  1.00 59.46  ? 228 LEU E C   1 
ATOM   6032  O O   . LEU E 1 21  ? -63.491  27.980  38.045  1.00 61.87  ? 228 LEU E O   1 
ATOM   6033  C CB  . LEU E 1 21  ? -65.702  25.773  37.218  1.00 50.25  ? 228 LEU E CB  1 
ATOM   6034  C CG  . LEU E 1 21  ? -66.738  26.346  38.185  1.00 53.48  ? 228 LEU E CG  1 
ATOM   6035  C CD1 . LEU E 1 21  ? -66.340  26.077  39.624  1.00 50.38  ? 228 LEU E CD1 1 
ATOM   6036  C CD2 . LEU E 1 21  ? -66.979  27.829  37.953  1.00 49.90  ? 228 LEU E CD2 1 
ATOM   6037  N N   . LEU E 1 22  ? -62.534  26.139  37.148  1.00 55.85  ? 229 LEU E N   1 
ATOM   6038  C CA  . LEU E 1 22  ? -61.301  26.261  37.965  1.00 54.11  ? 229 LEU E CA  1 
ATOM   6039  C C   . LEU E 1 22  ? -60.553  27.531  37.579  1.00 58.89  ? 229 LEU E C   1 
ATOM   6040  O O   . LEU E 1 22  ? -60.260  28.288  38.485  1.00 61.27  ? 229 LEU E O   1 
ATOM   6041  C CB  . LEU E 1 22  ? -60.441  25.016  37.760  1.00 51.75  ? 229 LEU E CB  1 
ATOM   6042  C CG  . LEU E 1 22  ? -60.853  23.804  38.586  1.00 57.89  ? 229 LEU E CG  1 
ATOM   6043  C CD1 . LEU E 1 22  ? -59.966  22.614  38.273  1.00 56.16  ? 229 LEU E CD1 1 
ATOM   6044  C CD2 . LEU E 1 22  ? -60.821  24.129  40.066  1.00 51.66  ? 229 LEU E CD2 1 
ATOM   6045  N N   . GLN E 1 23  ? -60.225  27.733  36.304  1.00 55.66  ? 230 GLN E N   1 
ATOM   6046  C CA  . GLN E 1 23  ? -59.633  28.998  35.891  1.00 52.01  ? 230 GLN E CA  1 
ATOM   6047  C C   . GLN E 1 23  ? -60.456  30.166  36.405  1.00 56.58  ? 230 GLN E C   1 
ATOM   6048  O O   . GLN E 1 23  ? -59.914  31.133  36.940  1.00 60.02  ? 230 GLN E O   1 
ATOM   6049  C CB  . GLN E 1 23  ? -59.535  29.082  34.371  1.00 59.42  ? 230 GLN E CB  1 
ATOM   6050  C CG  . GLN E 1 23  ? -58.839  27.930  33.711  1.00 63.27  ? 230 GLN E CG  1 
ATOM   6051  C CD  . GLN E 1 23  ? -57.337  27.967  33.886  1.00 64.28  ? 230 GLN E CD  1 
ATOM   6052  O OE1 . GLN E 1 23  ? -56.672  26.942  33.746  1.00 65.42  ? 230 GLN E OE1 1 
ATOM   6053  N NE2 . GLN E 1 23  ? -56.790  29.143  34.180  1.00 64.10  ? 230 GLN E NE2 1 
ATOM   6054  N N   . THR E 1 24  ? -61.774  30.100  36.242  1.00 57.01  ? 231 THR E N   1 
ATOM   6055  C CA  . THR E 1 24  ? -62.662  31.219  36.656  1.00 51.79  ? 231 THR E CA  1 
ATOM   6056  C C   . THR E 1 24  ? -62.436  31.540  38.134  1.00 57.13  ? 231 THR E C   1 
ATOM   6057  O O   . THR E 1 24  ? -62.348  32.731  38.466  1.00 63.88  ? 231 THR E O   1 
ATOM   6058  C CB  . THR E 1 24  ? -64.128  30.915  36.333  1.00 50.50  ? 231 THR E CB  1 
ATOM   6059  O OG1 . THR E 1 24  ? -64.241  30.753  34.922  1.00 55.72  ? 231 THR E OG1 1 
ATOM   6060  C CG2 . THR E 1 24  ? -65.083  31.996  36.783  1.00 46.08  ? 231 THR E CG2 1 
ATOM   6061  N N   . LEU E 1 25  ? -62.338  30.516  38.979  1.00 58.27  ? 232 LEU E N   1 
ATOM   6062  C CA  . LEU E 1 25  ? -62.118  30.759  40.401  1.00 53.16  ? 232 LEU E CA  1 
ATOM   6063  C C   . LEU E 1 25  ? -60.654  31.043  40.704  1.00 57.08  ? 232 LEU E C   1 
ATOM   6064  O O   . LEU E 1 25  ? -60.346  31.835  41.600  1.00 59.27  ? 232 LEU E O   1 
ATOM   6065  C CB  . LEU E 1 25  ? -62.592  29.562  41.228  1.00 50.98  ? 232 LEU E CB  1 
ATOM   6066  C CG  . LEU E 1 25  ? -64.063  29.156  41.203  1.00 52.50  ? 232 LEU E CG  1 
ATOM   6067  C CD1 . LEU E 1 25  ? -64.348  28.089  42.269  1.00 48.61  ? 232 LEU E CD1 1 
ATOM   6068  C CD2 . LEU E 1 25  ? -64.993  30.342  41.373  1.00 41.69  ? 232 LEU E CD2 1 
ATOM   6069  N N   . PHE E 1 26  ? -59.732  30.401  40.003  1.00 60.41  ? 233 PHE E N   1 
ATOM   6070  C CA  . PHE E 1 26  ? -58.291  30.700  40.200  1.00 65.33  ? 233 PHE E CA  1 
ATOM   6071  C C   . PHE E 1 26  ? -58.055  32.195  39.994  1.00 67.44  ? 233 PHE E C   1 
ATOM   6072  O O   . PHE E 1 26  ? -57.231  32.767  40.717  1.00 68.61  ? 233 PHE E O   1 
ATOM   6073  C CB  . PHE E 1 26  ? -57.461  29.842  39.246  1.00 63.75  ? 233 PHE E CB  1 
ATOM   6074  C CG  . PHE E 1 26  ? -55.983  30.115  39.199  1.00 64.14  ? 233 PHE E CG  1 
ATOM   6075  C CD1 . PHE E 1 26  ? -55.162  29.769  40.256  1.00 67.31  ? 233 PHE E CD1 1 
ATOM   6076  C CD2 . PHE E 1 26  ? -55.411  30.680  38.074  1.00 63.46  ? 233 PHE E CD2 1 
ATOM   6077  C CE1 . PHE E 1 26  ? -53.801  30.012  40.198  1.00 69.92  ? 233 PHE E CE1 1 
ATOM   6078  C CE2 . PHE E 1 26  ? -54.049  30.923  38.018  1.00 65.12  ? 233 PHE E CE2 1 
ATOM   6079  C CZ  . PHE E 1 26  ? -53.250  30.593  39.083  1.00 66.29  ? 233 PHE E CZ  1 
ATOM   6080  N N   . PHE E 1 27  ? -58.784  32.807  39.063  1.00 57.35  ? 234 PHE E N   1 
ATOM   6081  C CA  . PHE E 1 27  ? -58.566  34.241  38.741  1.00 58.71  ? 234 PHE E CA  1 
ATOM   6082  C C   . PHE E 1 27  ? -59.373  35.128  39.689  1.00 64.18  ? 234 PHE E C   1 
ATOM   6083  O O   . PHE E 1 27  ? -59.210  36.344  39.588  1.00 68.71  ? 234 PHE E O   1 
ATOM   6084  C CB  . PHE E 1 27  ? -58.755  34.479  37.245  1.00 63.00  ? 234 PHE E CB  1 
ATOM   6085  C CG  . PHE E 1 27  ? -57.642  33.896  36.413  1.00 64.08  ? 234 PHE E CG  1 
ATOM   6086  C CD1 . PHE E 1 27  ? -56.318  34.159  36.721  1.00 63.02  ? 234 PHE E CD1 1 
ATOM   6087  C CD2 . PHE E 1 27  ? -57.913  33.067  35.339  1.00 66.10  ? 234 PHE E CD2 1 
ATOM   6088  C CE1 . PHE E 1 27  ? -55.293  33.623  35.959  1.00 65.45  ? 234 PHE E CE1 1 
ATOM   6089  C CE2 . PHE E 1 27  ? -56.886  32.526  34.585  1.00 64.04  ? 234 PHE E CE2 1 
ATOM   6090  C CZ  . PHE E 1 27  ? -55.578  32.804  34.895  1.00 65.83  ? 234 PHE E CZ  1 
ATOM   6091  N N   . THR E 1 28  ? -60.257  34.566  40.514  1.00 64.09  ? 235 THR E N   1 
ATOM   6092  C CA  . THR E 1 28  ? -60.871  35.362  41.607  1.00 62.16  ? 235 THR E CA  1 
ATOM   6093  C C   . THR E 1 28  ? -59.715  35.368  42.592  1.00 67.55  ? 235 THR E C   1 
ATOM   6094  O O   . THR E 1 28  ? -59.668  34.472  43.428  1.00 67.30  ? 235 THR E O   1 
ATOM   6095  C CB  . THR E 1 28  ? -62.179  34.751  42.117  1.00 61.44  ? 235 THR E CB  1 
ATOM   6096  O OG1 . THR E 1 28  ? -62.968  34.346  40.999  1.00 67.78  ? 235 THR E OG1 1 
ATOM   6097  C CG2 . THR E 1 28  ? -62.972  35.712  42.973  1.00 57.08  ? 235 THR E CG2 1 
ATOM   6098  N N   . ASN E 1 29  ? -58.792  36.315  42.464  1.00 66.26  ? 236 ASN E N   1 
ATOM   6099  C CA  . ASN E 1 29  ? -57.522  36.257  43.194  1.00 67.89  ? 236 ASN E CA  1 
ATOM   6100  C C   . ASN E 1 29  ? -57.724  36.197  44.692  1.00 65.28  ? 236 ASN E C   1 
ATOM   6101  O O   . ASN E 1 29  ? -57.125  35.363  45.383  1.00 62.04  ? 236 ASN E O   1 
ATOM   6102  C CB  . ASN E 1 29  ? -56.660  37.466  42.852  1.00 70.25  ? 236 ASN E CB  1 
ATOM   6103  C CG  . ASN E 1 29  ? -56.002  37.321  41.533  1.00 72.42  ? 236 ASN E CG  1 
ATOM   6104  O OD1 . ASN E 1 29  ? -56.259  36.350  40.815  1.00 71.71  ? 236 ASN E OD1 1 
ATOM   6105  N ND2 . ASN E 1 29  ? -55.148  38.280  41.181  1.00 70.71  ? 236 ASN E ND2 1 
ATOM   6106  N N   . GLN E 1 30  ? -58.582  37.080  45.196  1.00 62.26  ? 237 GLN E N   1 
ATOM   6107  C CA  . GLN E 1 30  ? -58.882  37.121  46.646  1.00 60.47  ? 237 GLN E CA  1 
ATOM   6108  C C   . GLN E 1 30  ? -59.356  35.748  47.097  1.00 63.32  ? 237 GLN E C   1 
ATOM   6109  O O   . GLN E 1 30  ? -59.007  35.349  48.211  1.00 63.32  ? 237 GLN E O   1 
ATOM   6110  C CB  . GLN E 1 30  ? -59.981  38.142  46.911  1.00 62.65  ? 237 GLN E CB  1 
ATOM   6111  C CG  . GLN E 1 30  ? -59.747  38.999  48.142  1.00 68.19  ? 237 GLN E CG  1 
ATOM   6112  C CD  . GLN E 1 30  ? -61.016  39.698  48.558  1.00 71.52  ? 237 GLN E CD  1 
ATOM   6113  O OE1 . GLN E 1 30  ? -61.655  39.332  49.539  1.00 87.38  ? 237 GLN E OE1 1 
ATOM   6114  N NE2 . GLN E 1 30  ? -61.398  40.710  47.801  1.00 79.05  ? 237 GLN E NE2 1 
ATOM   6115  N N   . LEU E 1 31  ? -60.137  35.071  46.258  1.00 63.28  ? 238 LEU E N   1 
ATOM   6116  C CA  . LEU E 1 31  ? -60.561  33.712  46.598  1.00 66.33  ? 238 LEU E CA  1 
ATOM   6117  C C   . LEU E 1 31  ? -59.383  32.749  46.574  1.00 67.81  ? 238 LEU E C   1 
ATOM   6118  O O   . LEU E 1 31  ? -59.275  31.864  47.435  1.00 64.99  ? 238 LEU E O   1 
ATOM   6119  C CB  . LEU E 1 31  ? -61.651  33.212  45.644  1.00 64.23  ? 238 LEU E CB  1 
ATOM   6120  C CG  . LEU E 1 31  ? -62.029  31.732  45.872  1.00 65.07  ? 238 LEU E CG  1 
ATOM   6121  C CD1 . LEU E 1 31  ? -62.692  31.483  47.254  1.00 59.65  ? 238 LEU E CD1 1 
ATOM   6122  C CD2 . LEU E 1 31  ? -62.886  31.177  44.750  1.00 56.11  ? 238 LEU E CD2 1 
ATOM   6123  N N   . ARG E 1 32  ? -58.505  32.893  45.581  1.00 61.06  ? 239 ARG E N   1 
ATOM   6124  C CA  . ARG E 1 32  ? -57.333  32.035  45.516  1.00 60.98  ? 239 ARG E CA  1 
ATOM   6125  C C   . ARG E 1 32  ? -56.496  32.163  46.785  1.00 63.61  ? 239 ARG E C   1 
ATOM   6126  O O   . ARG E 1 32  ? -56.182  31.161  47.435  1.00 62.41  ? 239 ARG E O   1 
ATOM   6127  C CB  . ARG E 1 32  ? -56.522  32.384  44.271  1.00 66.16  ? 239 ARG E CB  1 
ATOM   6128  C CG  . ARG E 1 32  ? -55.318  31.499  44.035  1.00 68.10  ? 239 ARG E CG  1 
ATOM   6129  C CD  . ARG E 1 32  ? -54.226  32.284  43.331  1.00 67.30  ? 239 ARG E CD  1 
ATOM   6130  N NE  . ARG E 1 32  ? -54.607  32.663  41.972  1.00 65.96  ? 239 ARG E NE  1 
ATOM   6131  C CZ  . ARG E 1 32  ? -53.858  33.413  41.175  1.00 61.62  ? 239 ARG E CZ  1 
ATOM   6132  N NH1 . ARG E 1 32  ? -52.701  33.873  41.606  1.00 68.38  ? 239 ARG E NH1 1 
ATOM   6133  N NH2 . ARG E 1 32  ? -54.262  33.708  39.952  1.00 62.43  ? 239 ARG E NH2 1 
ATOM   6134  N N   . LYS E 1 33  ? -56.167  33.400  47.178  1.00 65.70  ? 240 LYS E N   1 
ATOM   6135  C CA  . LYS E 1 33  ? -55.317  33.615  48.349  1.00 66.79  ? 240 LYS E CA  1 
ATOM   6136  C C   . LYS E 1 33  ? -55.956  33.040  49.609  1.00 66.97  ? 240 LYS E C   1 
ATOM   6137  O O   . LYS E 1 33  ? -55.271  32.434  50.443  1.00 68.33  ? 240 LYS E O   1 
ATOM   6138  C CB  . LYS E 1 33  ? -55.017  35.113  48.523  1.00 59.52  ? 240 LYS E CB  1 
ATOM   6139  N N   . ALA E 1 34  ? -57.270  33.217  49.757  1.00 66.92  ? 241 ALA E N   1 
ATOM   6140  C CA  . ALA E 1 34  ? -57.992  32.634  50.885  1.00 64.46  ? 241 ALA E CA  1 
ATOM   6141  C C   . ALA E 1 34  ? -57.869  31.112  50.911  1.00 63.27  ? 241 ALA E C   1 
ATOM   6142  O O   . ALA E 1 34  ? -57.575  30.524  51.957  1.00 65.70  ? 241 ALA E O   1 
ATOM   6143  C CB  . ALA E 1 34  ? -59.460  33.049  50.819  1.00 69.15  ? 241 ALA E CB  1 
ATOM   6144  N N   . VAL E 1 35  ? -58.097  30.452  49.771  1.00 60.51  ? 242 VAL E N   1 
ATOM   6145  C CA  . VAL E 1 35  ? -57.954  28.994  49.724  1.00 70.61  ? 242 VAL E CA  1 
ATOM   6146  C C   . VAL E 1 35  ? -56.534  28.580  50.117  1.00 70.19  ? 242 VAL E C   1 
ATOM   6147  O O   . VAL E 1 35  ? -56.321  27.494  50.683  1.00 61.11  ? 242 VAL E O   1 
ATOM   6148  C CB  . VAL E 1 35  ? -58.354  28.450  48.328  1.00 68.28  ? 242 VAL E CB  1 
ATOM   6149  C CG1 . VAL E 1 35  ? -57.901  26.997  48.128  1.00 64.23  ? 242 VAL E CG1 1 
ATOM   6150  C CG2 . VAL E 1 35  ? -59.860  28.543  48.131  1.00 64.73  ? 242 VAL E CG2 1 
ATOM   6151  N N   . TYR E 1 36  ? -55.549  29.450  49.857  1.00 69.66  ? 243 TYR E N   1 
ATOM   6152  C CA  . TYR E 1 36  ? -54.163  29.126  50.187  1.00 71.09  ? 243 TYR E CA  1 
ATOM   6153  C C   . TYR E 1 36  ? -53.956  29.057  51.692  1.00 68.01  ? 243 TYR E C   1 
ATOM   6154  O O   . TYR E 1 36  ? -53.238  28.179  52.185  1.00 68.55  ? 243 TYR E O   1 
ATOM   6155  C CB  . TYR E 1 36  ? -53.214  30.148  49.560  1.00 68.62  ? 243 TYR E CB  1 
ATOM   6156  C CG  . TYR E 1 36  ? -52.861  29.852  48.115  1.00 69.40  ? 243 TYR E CG  1 
ATOM   6157  C CD1 . TYR E 1 36  ? -52.779  28.547  47.650  1.00 64.93  ? 243 TYR E CD1 1 
ATOM   6158  C CD2 . TYR E 1 36  ? -52.617  30.883  47.217  1.00 67.06  ? 243 TYR E CD2 1 
ATOM   6159  C CE1 . TYR E 1 36  ? -52.460  28.283  46.327  1.00 68.38  ? 243 TYR E CE1 1 
ATOM   6160  C CE2 . TYR E 1 36  ? -52.295  30.628  45.898  1.00 65.95  ? 243 TYR E CE2 1 
ATOM   6161  C CZ  . TYR E 1 36  ? -52.217  29.331  45.454  1.00 70.42  ? 243 TYR E CZ  1 
ATOM   6162  O OH  . TYR E 1 36  ? -51.899  29.086  44.131  1.00 69.77  ? 243 TYR E OH  1 
ATOM   6163  N N   . MET E 1 37  ? -54.598  29.945  52.447  1.00 63.72  ? 244 MET E N   1 
ATOM   6164  C CA  . MET E 1 37  ? -54.403  29.951  53.886  1.00 67.73  ? 244 MET E CA  1 
ATOM   6165  C C   . MET E 1 37  ? -55.443  29.128  54.625  1.00 69.87  ? 244 MET E C   1 
ATOM   6166  O O   . MET E 1 37  ? -55.649  29.330  55.828  1.00 69.57  ? 244 MET E O   1 
ATOM   6167  C CB  . MET E 1 37  ? -54.349  31.388  54.397  1.00 73.97  ? 244 MET E CB  1 
ATOM   6168  C CG  . MET E 1 37  ? -52.973  32.009  54.147  1.00 75.84  ? 244 MET E CG  1 
ATOM   6169  S SD  . MET E 1 37  ? -53.026  33.797  54.018  1.00 111.04 ? 244 MET E SD  1 
ATOM   6170  C CE  . MET E 1 37  ? -54.566  34.162  54.867  1.00 89.49  ? 244 MET E CE  1 
ATOM   6171  N N   . MET E 1 38  ? -56.074  28.183  53.944  1.00 74.21  ? 245 MET E N   1 
ATOM   6172  C CA  . MET E 1 38  ? -56.924  27.222  54.626  1.00 70.67  ? 245 MET E CA  1 
ATOM   6173  C C   . MET E 1 38  ? -56.061  26.187  55.326  1.00 73.19  ? 245 MET E C   1 
ATOM   6174  O O   . MET E 1 38  ? -55.166  25.617  54.702  1.00 76.49  ? 245 MET E O   1 
ATOM   6175  C CB  . MET E 1 38  ? -57.848  26.544  53.646  1.00 67.34  ? 245 MET E CB  1 
ATOM   6176  C CG  . MET E 1 38  ? -58.738  27.520  52.921  1.00 72.23  ? 245 MET E CG  1 
ATOM   6177  S SD  . MET E 1 38  ? -59.942  26.639  51.950  1.00 72.69  ? 245 MET E SD  1 
ATOM   6178  C CE  . MET E 1 38  ? -60.749  25.707  53.258  1.00 64.62  ? 245 MET E CE  1 
ATOM   6179  N N   . PRO E 1 39  ? -56.247  25.927  56.654  1.00 70.94  ? 246 PRO E N   1 
ATOM   6180  C CA  . PRO E 1 39  ? -55.487  24.885  57.338  1.00 74.28  ? 246 PRO E CA  1 
ATOM   6181  C C   . PRO E 1 39  ? -55.733  23.482  56.774  1.00 74.91  ? 246 PRO E C   1 
ATOM   6182  O O   . PRO E 1 39  ? -56.747  22.896  57.072  1.00 75.71  ? 246 PRO E O   1 
ATOM   6183  C CB  . PRO E 1 39  ? -55.958  24.936  58.799  1.00 71.53  ? 246 PRO E CB  1 
ATOM   6184  C CG  . PRO E 1 39  ? -57.281  25.629  58.759  1.00 75.97  ? 246 PRO E CG  1 
ATOM   6185  C CD  . PRO E 1 39  ? -57.077  26.644  57.665  1.00 70.80  ? 246 PRO E CD  1 
ATOM   6186  N N   . THR E 1 40  ? -54.775  22.968  56.006  1.00 75.21  ? 247 THR E N   1 
ATOM   6187  C CA  . THR E 1 40  ? -54.953  21.638  55.372  1.00 81.92  ? 247 THR E CA  1 
ATOM   6188  C C   . THR E 1 40  ? -53.843  20.681  55.794  1.00 86.72  ? 247 THR E C   1 
ATOM   6189  O O   . THR E 1 40  ? -53.696  19.646  55.135  1.00 91.20  ? 247 THR E O   1 
ATOM   6190  C CB  . THR E 1 40  ? -54.972  21.763  53.848  1.00 84.17  ? 247 THR E CB  1 
ATOM   6191  O OG1 . THR E 1 40  ? -53.821  22.502  53.440  1.00 86.19  ? 247 THR E OG1 1 
ATOM   6192  C CG2 . THR E 1 40  ? -56.231  22.436  53.353  1.00 77.63  ? 247 THR E CG2 1 
ATOM   6193  N N   . GLU E 1 41  ? -53.097  21.020  56.843  1.00 91.76  ? 248 GLU E N   1 
ATOM   6194  C CA  . GLU E 1 41  ? -51.964  20.174  57.288  1.00 93.61  ? 248 GLU E CA  1 
ATOM   6195  C C   . GLU E 1 41  ? -52.477  18.752  57.506  1.00 97.48  ? 248 GLU E C   1 
ATOM   6196  O O   . GLU E 1 41  ? -53.219  18.539  58.484  1.00 97.79  ? 248 GLU E O   1 
ATOM   6197  C CB  . GLU E 1 41  ? -51.353  20.764  58.557  1.00 92.74  ? 248 GLU E CB  1 
ATOM   6198  N N   . GLY E 1 42  ? -52.103  17.824  56.626  1.00 93.03  ? 249 GLY E N   1 
ATOM   6199  C CA  . GLY E 1 42  ? -52.623  16.448  56.719  1.00 97.07  ? 249 GLY E CA  1 
ATOM   6200  C C   . GLY E 1 42  ? -54.138  16.434  56.619  1.00 99.99  ? 249 GLY E C   1 
ATOM   6201  O O   . GLY E 1 42  ? -54.641  16.787  55.537  1.00 105.20 ? 249 GLY E O   1 
ATOM   6202  N N   . SER E 1 45  ? -54.400  14.487  50.479  1.00 100.30 ? 252 SER E N   1 
ATOM   6203  C CA  . SER E 1 45  ? -54.575  15.116  49.170  1.00 101.58 ? 252 SER E CA  1 
ATOM   6204  C C   . SER E 1 45  ? -55.676  14.415  48.377  1.00 103.72 ? 252 SER E C   1 
ATOM   6205  O O   . SER E 1 45  ? -56.399  15.044  47.617  1.00 96.48  ? 252 SER E O   1 
ATOM   6206  C CB  . SER E 1 45  ? -53.266  15.100  48.383  1.00 101.88 ? 252 SER E CB  1 
ATOM   6207  O OG  . SER E 1 45  ? -53.427  15.706  47.110  1.00 108.91 ? 252 SER E OG  1 
ATOM   6208  N N   . SER E 1 46  ? -55.841  13.110  48.565  1.00 107.29 ? 253 SER E N   1 
ATOM   6209  C CA  . SER E 1 46  ? -57.006  12.436  47.936  1.00 96.15  ? 253 SER E CA  1 
ATOM   6210  C C   . SER E 1 46  ? -58.113  12.419  48.981  1.00 96.72  ? 253 SER E C   1 
ATOM   6211  O O   . SER E 1 46  ? -59.025  11.584  48.863  1.00 98.84  ? 253 SER E O   1 
ATOM   6212  C CB  . SER E 1 46  ? -56.659  11.051  47.495  1.00 97.81  ? 253 SER E CB  1 
ATOM   6213  O OG  . SER E 1 46  ? -56.381  10.216  48.610  1.00 102.05 ? 253 SER E OG  1 
ATOM   6214  N N   . LYS E 1 47  ? -58.038  13.326  49.954  1.00 90.11  ? 254 LYS E N   1 
ATOM   6215  C CA  . LYS E 1 47  ? -58.978  13.273  51.061  1.00 93.17  ? 254 LYS E CA  1 
ATOM   6216  C C   . LYS E 1 47  ? -59.399  14.663  51.491  1.00 88.18  ? 254 LYS E C   1 
ATOM   6217  O O   . LYS E 1 47  ? -59.839  14.841  52.633  1.00 89.55  ? 254 LYS E O   1 
ATOM   6218  C CB  . LYS E 1 47  ? -58.384  12.508  52.259  1.00 101.57 ? 254 LYS E CB  1 
ATOM   6219  N N   . SER E 1 48  ? -59.226  15.635  50.590  1.00 81.89  ? 255 SER E N   1 
ATOM   6220  C CA  . SER E 1 48  ? -59.493  17.048  50.949  1.00 75.84  ? 255 SER E CA  1 
ATOM   6221  C C   . SER E 1 48  ? -59.746  17.890  49.707  1.00 77.67  ? 255 SER E C   1 
ATOM   6222  O O   . SER E 1 48  ? -58.791  18.106  48.955  1.00 82.08  ? 255 SER E O   1 
ATOM   6223  C CB  . SER E 1 48  ? -58.321  17.603  51.698  1.00 75.85  ? 255 SER E CB  1 
ATOM   6224  O OG  . SER E 1 48  ? -58.681  18.750  52.447  1.00 77.03  ? 255 SER E OG  1 
ATOM   6225  N N   . VAL E 1 49  ? -60.979  18.357  49.507  1.00 71.33  ? 256 VAL E N   1 
ATOM   6226  C CA  . VAL E 1 49  ? -61.245  19.289  48.419  1.00 67.28  ? 256 VAL E CA  1 
ATOM   6227  C C   . VAL E 1 49  ? -60.398  20.546  48.595  1.00 66.17  ? 256 VAL E C   1 
ATOM   6228  O O   . VAL E 1 49  ? -59.944  21.109  47.590  1.00 65.15  ? 256 VAL E O   1 
ATOM   6229  C CB  . VAL E 1 49  ? -62.743  19.616  48.321  1.00 64.87  ? 256 VAL E CB  1 
ATOM   6230  C CG1 . VAL E 1 49  ? -63.012  20.483  47.116  1.00 66.80  ? 256 VAL E CG1 1 
ATOM   6231  C CG2 . VAL E 1 49  ? -63.522  18.336  48.206  1.00 64.96  ? 256 VAL E CG2 1 
ATOM   6232  N N   . PRO E 1 50  ? -60.134  21.021  49.837  1.00 65.97  ? 257 PRO E N   1 
ATOM   6233  C CA  . PRO E 1 50  ? -59.227  22.166  50.003  1.00 66.02  ? 257 PRO E CA  1 
ATOM   6234  C C   . PRO E 1 50  ? -57.793  21.908  49.574  1.00 69.42  ? 257 PRO E C   1 
ATOM   6235  O O   . PRO E 1 50  ? -57.233  22.707  48.811  1.00 66.18  ? 257 PRO E O   1 
ATOM   6236  C CB  . PRO E 1 50  ? -59.304  22.449  51.504  1.00 61.73  ? 257 PRO E CB  1 
ATOM   6237  C CG  . PRO E 1 50  ? -60.622  22.034  51.867  1.00 61.49  ? 257 PRO E CG  1 
ATOM   6238  C CD  . PRO E 1 50  ? -60.886  20.792  51.080  1.00 63.70  ? 257 PRO E CD  1 
ATOM   6239  N N   . LEU E 1 51  ? -57.178  20.830  50.078  1.00 65.02  ? 258 LEU E N   1 
ATOM   6240  C CA  . LEU E 1 51  ? -55.824  20.498  49.650  1.00 69.00  ? 258 LEU E CA  1 
ATOM   6241  C C   . LEU E 1 51  ? -55.757  20.396  48.133  1.00 70.59  ? 258 LEU E C   1 
ATOM   6242  O O   . LEU E 1 51  ? -54.947  21.070  47.482  1.00 67.91  ? 258 LEU E O   1 
ATOM   6243  C CB  . LEU E 1 51  ? -55.364  19.189  50.294  1.00 79.12  ? 258 LEU E CB  1 
ATOM   6244  N N   . ALA E 1 52  ? -56.635  19.574  47.555  1.00 64.67  ? 259 ALA E N   1 
ATOM   6245  C CA  . ALA E 1 52  ? -56.680  19.413  46.110  1.00 63.77  ? 259 ALA E CA  1 
ATOM   6246  C C   . ALA E 1 52  ? -56.809  20.758  45.409  1.00 66.41  ? 259 ALA E C   1 
ATOM   6247  O O   . ALA E 1 52  ? -56.111  21.030  44.424  1.00 64.95  ? 259 ALA E O   1 
ATOM   6248  C CB  . ALA E 1 52  ? -57.841  18.492  45.736  1.00 70.78  ? 259 ALA E CB  1 
ATOM   6249  N N   . LEU E 1 53  ? -57.694  21.617  45.903  1.00 66.27  ? 260 LEU E N   1 
ATOM   6250  C CA  . LEU E 1 53  ? -57.897  22.929  45.241  1.00 63.76  ? 260 LEU E CA  1 
ATOM   6251  C C   . LEU E 1 53  ? -56.624  23.746  45.421  1.00 66.67  ? 260 LEU E C   1 
ATOM   6252  O O   . LEU E 1 53  ? -56.237  24.409  44.467  1.00 63.43  ? 260 LEU E O   1 
ATOM   6253  C CB  . LEU E 1 53  ? -59.113  23.644  45.828  1.00 63.19  ? 260 LEU E CB  1 
ATOM   6254  C CG  . LEU E 1 53  ? -59.921  24.469  44.834  1.00 61.97  ? 260 LEU E CG  1 
ATOM   6255  C CD1 . LEU E 1 53  ? -60.418  23.596  43.700  1.00 60.11  ? 260 LEU E CD1 1 
ATOM   6256  C CD2 . LEU E 1 53  ? -61.083  25.152  45.526  1.00 66.61  ? 260 LEU E CD2 1 
ATOM   6257  N N   . GLN E 1 54  ? -55.989  23.668  46.591  1.00 67.41  ? 261 GLN E N   1 
ATOM   6258  C CA  . GLN E 1 54  ? -54.718  24.351  46.771  1.00 65.86  ? 261 GLN E CA  1 
ATOM   6259  C C   . GLN E 1 54  ? -53.699  23.893  45.737  1.00 66.91  ? 261 GLN E C   1 
ATOM   6260  O O   . GLN E 1 54  ? -52.996  24.713  45.139  1.00 68.34  ? 261 GLN E O   1 
ATOM   6261  C CB  . GLN E 1 54  ? -54.205  24.101  48.183  1.00 68.20  ? 261 GLN E CB  1 
ATOM   6262  C CG  . GLN E 1 54  ? -54.961  24.878  49.225  1.00 73.34  ? 261 GLN E CG  1 
ATOM   6263  C CD  . GLN E 1 54  ? -54.597  24.461  50.620  1.00 72.29  ? 261 GLN E CD  1 
ATOM   6264  O OE1 . GLN E 1 54  ? -54.304  23.291  50.873  1.00 69.60  ? 261 GLN E OE1 1 
ATOM   6265  N NE2 . GLN E 1 54  ? -54.612  25.417  51.544  1.00 71.52  ? 261 GLN E NE2 1 
ATOM   6266  N N   . ARG E 1 55  ? -53.614  22.585  45.518  1.00 65.22  ? 262 ARG E N   1 
ATOM   6267  C CA  . ARG E 1 55  ? -52.614  22.051  44.564  1.00 68.91  ? 262 ARG E CA  1 
ATOM   6268  C C   . ARG E 1 55  ? -52.940  22.579  43.174  1.00 71.23  ? 262 ARG E C   1 
ATOM   6269  O O   . ARG E 1 55  ? -52.062  23.188  42.569  1.00 75.83  ? 262 ARG E O   1 
ATOM   6270  C CB  . ARG E 1 55  ? -52.602  20.522  44.558  1.00 72.59  ? 262 ARG E CB  1 
ATOM   6271  C CG  . ARG E 1 55  ? -51.514  19.913  43.688  1.00 74.39  ? 262 ARG E CG  1 
ATOM   6272  C CD  . ARG E 1 55  ? -51.479  18.401  43.764  1.00 76.99  ? 262 ARG E CD  1 
ATOM   6273  N NE  . ARG E 1 55  ? -51.383  17.909  45.130  1.00 87.87  ? 262 ARG E NE  1 
ATOM   6274  N N   . VAL E 1 56  ? -54.154  22.329  42.693  1.00 66.79  ? 263 VAL E N   1 
ATOM   6275  C CA  . VAL E 1 56  ? -54.551  22.805  41.341  1.00 61.47  ? 263 VAL E CA  1 
ATOM   6276  C C   . VAL E 1 56  ? -54.185  24.285  41.249  1.00 65.79  ? 263 VAL E C   1 
ATOM   6277  O O   . VAL E 1 56  ? -53.489  24.642  40.302  1.00 67.04  ? 263 VAL E O   1 
ATOM   6278  C CB  . VAL E 1 56  ? -56.041  22.528  41.068  1.00 61.11  ? 263 VAL E CB  1 
ATOM   6279  C CG1 . VAL E 1 56  ? -56.538  23.222  39.816  1.00 61.39  ? 263 VAL E CG1 1 
ATOM   6280  C CG2 . VAL E 1 56  ? -56.332  21.039  40.991  1.00 51.33  ? 263 VAL E CG2 1 
ATOM   6281  N N   . PHE E 1 57  ? -54.558  25.084  42.250  1.00 63.56  ? 264 PHE E N   1 
ATOM   6282  C CA  . PHE E 1 57  ? -54.280  26.513  42.228  1.00 67.30  ? 264 PHE E CA  1 
ATOM   6283  C C   . PHE E 1 57  ? -52.778  26.776  42.154  1.00 72.86  ? 264 PHE E C   1 
ATOM   6284  O O   . PHE E 1 57  ? -52.288  27.391  41.197  1.00 70.73  ? 264 PHE E O   1 
ATOM   6285  C CB  . PHE E 1 57  ? -54.899  27.182  43.459  1.00 62.14  ? 264 PHE E CB  1 
ATOM   6286  C CG  . PHE E 1 57  ? -56.370  27.435  43.327  1.00 64.03  ? 264 PHE E CG  1 
ATOM   6287  C CD1 . PHE E 1 57  ? -57.048  27.055  42.181  1.00 61.52  ? 264 PHE E CD1 1 
ATOM   6288  C CD2 . PHE E 1 57  ? -57.074  28.056  44.341  1.00 62.65  ? 264 PHE E CD2 1 
ATOM   6289  C CE1 . PHE E 1 57  ? -58.389  27.286  42.056  1.00 59.67  ? 264 PHE E CE1 1 
ATOM   6290  C CE2 . PHE E 1 57  ? -58.423  28.287  44.223  1.00 60.60  ? 264 PHE E CE2 1 
ATOM   6291  C CZ  . PHE E 1 57  ? -59.083  27.901  43.081  1.00 62.51  ? 264 PHE E CZ  1 
ATOM   6292  N N   . TYR E 1 58  ? -52.031  26.306  43.158  1.00 66.36  ? 265 TYR E N   1 
ATOM   6293  C CA  . TYR E 1 58  ? -50.584  26.464  43.152  1.00 67.57  ? 265 TYR E CA  1 
ATOM   6294  C C   . TYR E 1 58  ? -49.998  26.138  41.785  1.00 74.41  ? 265 TYR E C   1 
ATOM   6295  O O   . TYR E 1 58  ? -49.299  26.965  41.187  1.00 75.20  ? 265 TYR E O   1 
ATOM   6296  C CB  . TYR E 1 58  ? -49.946  25.582  44.227  1.00 73.61  ? 265 TYR E CB  1 
ATOM   6297  C CG  . TYR E 1 58  ? -48.441  25.754  44.302  1.00 82.76  ? 265 TYR E CG  1 
ATOM   6298  C CD1 . TYR E 1 58  ? -47.884  26.929  44.807  1.00 87.61  ? 265 TYR E CD1 1 
ATOM   6299  C CD2 . TYR E 1 58  ? -47.574  24.756  43.848  1.00 83.51  ? 265 TYR E CD2 1 
ATOM   6300  C CE1 . TYR E 1 58  ? -46.506  27.108  44.862  1.00 92.16  ? 265 TYR E CE1 1 
ATOM   6301  C CE2 . TYR E 1 58  ? -46.191  24.923  43.906  1.00 83.02  ? 265 TYR E CE2 1 
ATOM   6302  C CZ  . TYR E 1 58  ? -45.670  26.104  44.411  1.00 91.37  ? 265 TYR E CZ  1 
ATOM   6303  O OH  . TYR E 1 58  ? -44.309  26.294  44.476  1.00 98.23  ? 265 TYR E OH  1 
ATOM   6304  N N   . GLU E 1 59  ? -50.305  24.949  41.252  1.00 71.05  ? 266 GLU E N   1 
ATOM   6305  C CA  . GLU E 1 59  ? -49.666  24.528  40.010  1.00 71.97  ? 266 GLU E CA  1 
ATOM   6306  C C   . GLU E 1 59  ? -50.094  25.380  38.819  1.00 74.19  ? 266 GLU E C   1 
ATOM   6307  O O   . GLU E 1 59  ? -49.312  25.554  37.876  1.00 67.87  ? 266 GLU E O   1 
ATOM   6308  C CB  . GLU E 1 59  ? -49.954  23.058  39.760  1.00 72.63  ? 266 GLU E CB  1 
ATOM   6309  C CG  . GLU E 1 59  ? -49.482  22.196  40.896  1.00 76.76  ? 266 GLU E CG  1 
ATOM   6310  C CD  . GLU E 1 59  ? -48.785  20.932  40.430  1.00 90.58  ? 266 GLU E CD  1 
ATOM   6311  O OE1 . GLU E 1 59  ? -49.284  19.823  40.747  1.00 85.40  ? 266 GLU E OE1 1 
ATOM   6312  O OE2 . GLU E 1 59  ? -47.734  21.053  39.757  1.00 93.53  ? 266 GLU E OE2 1 
ATOM   6313  N N   . LEU E 1 60  ? -51.313  25.932  38.845  1.00 72.80  ? 267 LEU E N   1 
ATOM   6314  C CA  . LEU E 1 60  ? -51.728  26.858  37.794  1.00 69.16  ? 267 LEU E CA  1 
ATOM   6315  C C   . LEU E 1 60  ? -50.916  28.146  37.830  1.00 76.50  ? 267 LEU E C   1 
ATOM   6316  O O   . LEU E 1 60  ? -50.703  28.784  36.788  1.00 75.89  ? 267 LEU E O   1 
ATOM   6317  C CB  . LEU E 1 60  ? -53.213  27.177  37.935  1.00 70.67  ? 267 LEU E CB  1 
ATOM   6318  C CG  . LEU E 1 60  ? -54.207  26.129  37.448  1.00 67.66  ? 267 LEU E CG  1 
ATOM   6319  C CD1 . LEU E 1 60  ? -55.507  26.292  38.205  1.00 62.97  ? 267 LEU E CD1 1 
ATOM   6320  C CD2 . LEU E 1 60  ? -54.416  26.269  35.957  1.00 61.94  ? 267 LEU E CD2 1 
ATOM   6321  N N   . GLN E 1 61  ? -50.407  28.513  39.005  1.00 79.50  ? 268 GLN E N   1 
ATOM   6322  C CA  . GLN E 1 61  ? -49.632  29.771  39.170  1.00 77.24  ? 268 GLN E CA  1 
ATOM   6323  C C   . GLN E 1 61  ? -48.149  29.515  38.940  1.00 74.12  ? 268 GLN E C   1 
ATOM   6324  O O   . GLN E 1 61  ? -47.472  30.421  38.439  1.00 75.30  ? 268 GLN E O   1 
ATOM   6325  C CB  . GLN E 1 61  ? -49.813  30.266  40.602  1.00 75.30  ? 268 GLN E CB  1 
ATOM   6326  C CG  . GLN E 1 61  ? -49.787  31.775  40.770  1.00 75.29  ? 268 GLN E CG  1 
ATOM   6327  C CD  . GLN E 1 61  ? -49.871  32.157  42.227  1.00 76.54  ? 268 GLN E CD  1 
ATOM   6328  O OE1 . GLN E 1 61  ? -50.560  31.520  43.018  1.00 71.74  ? 268 GLN E OE1 1 
ATOM   6329  N NE2 . GLN E 1 61  ? -49.165  33.212  42.595  1.00 81.46  ? 268 GLN E NE2 1 
ATOM   6330  N N   . HIS E 1 62  ? -47.673  28.324  39.282  1.00 74.66  ? 269 HIS E N   1 
ATOM   6331  C CA  . HIS E 1 62  ? -46.249  28.012  39.212  1.00 74.76  ? 269 HIS E CA  1 
ATOM   6332  C C   . HIS E 1 62  ? -45.864  27.203  37.975  1.00 78.98  ? 269 HIS E C   1 
ATOM   6333  O O   . HIS E 1 62  ? -44.934  27.586  37.266  1.00 85.19  ? 269 HIS E O   1 
ATOM   6334  C CB  . HIS E 1 62  ? -45.818  27.264  40.485  1.00 79.09  ? 269 HIS E CB  1 
ATOM   6335  N N   . SER E 1 63  ? -46.555  26.099  37.688  1.00 82.56  ? 270 SER E N   1 
ATOM   6336  C CA  . SER E 1 63  ? -46.108  25.191  36.638  1.00 81.76  ? 270 SER E CA  1 
ATOM   6337  C C   . SER E 1 63  ? -46.315  25.801  35.249  1.00 85.05  ? 270 SER E C   1 
ATOM   6338  O O   . SER E 1 63  ? -47.002  26.815  35.071  1.00 80.89  ? 270 SER E O   1 
ATOM   6339  C CB  . SER E 1 63  ? -46.834  23.849  36.740  1.00 85.37  ? 270 SER E CB  1 
ATOM   6340  O OG  . SER E 1 63  ? -46.883  23.194  35.483  1.00 83.62  ? 270 SER E OG  1 
ATOM   6341  N N   . ASP E 1 64  ? -45.626  25.204  34.273  1.00 91.43  ? 271 ASP E N   1 
ATOM   6342  C CA  . ASP E 1 64  ? -45.650  25.717  32.882  1.00 91.11  ? 271 ASP E CA  1 
ATOM   6343  C C   . ASP E 1 64  ? -46.315  24.693  31.969  1.00 88.94  ? 271 ASP E C   1 
ATOM   6344  O O   . ASP E 1 64  ? -46.799  25.087  30.898  1.00 91.37  ? 271 ASP E O   1 
ATOM   6345  C CB  . ASP E 1 64  ? -44.223  25.972  32.403  1.00 88.98  ? 271 ASP E CB  1 
ATOM   6346  C CG  . ASP E 1 64  ? -43.213  24.985  32.961  1.00 95.27  ? 271 ASP E CG  1 
ATOM   6347  O OD1 . ASP E 1 64  ? -42.717  25.224  34.078  1.00 93.19  ? 271 ASP E OD1 1 
ATOM   6348  O OD2 . ASP E 1 64  ? -42.937  23.982  32.278  1.00 95.45  ? 271 ASP E OD2 1 
ATOM   6349  N N   . LYS E 1 65  ? -46.313  23.427  32.374  1.00 83.94  ? 272 LYS E N   1 
ATOM   6350  C CA  . LYS E 1 65  ? -46.967  22.360  31.582  1.00 88.63  ? 272 LYS E CA  1 
ATOM   6351  C C   . LYS E 1 65  ? -48.409  22.192  32.069  1.00 87.25  ? 272 LYS E C   1 
ATOM   6352  O O   . LYS E 1 65  ? -48.653  22.451  33.261  1.00 81.45  ? 272 LYS E O   1 
ATOM   6353  C CB  . LYS E 1 65  ? -46.160  21.071  31.732  1.00 82.35  ? 272 LYS E CB  1 
ATOM   6354  N N   . PRO E 1 66  ? -49.365  21.779  31.206  1.00 83.80  ? 273 PRO E N   1 
ATOM   6355  C CA  . PRO E 1 66  ? -50.762  21.557  31.601  1.00 80.12  ? 273 PRO E CA  1 
ATOM   6356  C C   . PRO E 1 66  ? -50.958  20.975  33.008  1.00 79.03  ? 273 PRO E C   1 
ATOM   6357  O O   . PRO E 1 66  ? -50.281  20.032  33.358  1.00 71.19  ? 273 PRO E O   1 
ATOM   6358  C CB  . PRO E 1 66  ? -51.228  20.572  30.529  1.00 74.83  ? 273 PRO E CB  1 
ATOM   6359  C CG  . PRO E 1 66  ? -50.537  21.067  29.288  1.00 78.65  ? 273 PRO E CG  1 
ATOM   6360  C CD  . PRO E 1 66  ? -49.181  21.537  29.772  1.00 78.21  ? 273 PRO E CD  1 
ATOM   6361  N N   . VAL E 1 67  ? -51.904  21.538  33.759  1.00 76.91  ? 274 VAL E N   1 
ATOM   6362  C CA  . VAL E 1 67  ? -52.132  21.107  35.170  1.00 70.78  ? 274 VAL E CA  1 
ATOM   6363  C C   . VAL E 1 67  ? -53.192  20.008  35.204  1.00 69.12  ? 274 VAL E C   1 
ATOM   6364  O O   . VAL E 1 67  ? -54.188  20.125  34.513  1.00 69.04  ? 274 VAL E O   1 
ATOM   6365  C CB  . VAL E 1 67  ? -52.506  22.315  36.050  1.00 69.54  ? 274 VAL E CB  1 
ATOM   6366  C CG1 . VAL E 1 67  ? -52.739  21.938  37.503  1.00 70.44  ? 274 VAL E CG1 1 
ATOM   6367  C CG2 . VAL E 1 67  ? -51.460  23.409  35.951  1.00 71.61  ? 274 VAL E CG2 1 
ATOM   6368  N N   . GLY E 1 68  ? -52.965  18.974  36.000  1.00 60.64  ? 275 GLY E N   1 
ATOM   6369  C CA  . GLY E 1 68  ? -53.894  17.873  36.097  1.00 59.13  ? 275 GLY E CA  1 
ATOM   6370  C C   . GLY E 1 68  ? -54.870  18.059  37.229  1.00 61.96  ? 275 GLY E C   1 
ATOM   6371  O O   . GLY E 1 68  ? -54.694  18.903  38.112  1.00 59.15  ? 275 GLY E O   1 
ATOM   6372  N N   . THR E 1 69  ? -55.935  17.271  37.189  1.00 60.09  ? 276 THR E N   1 
ATOM   6373  C CA  . THR E 1 69  ? -56.991  17.412  38.170  1.00 57.27  ? 276 THR E CA  1 
ATOM   6374  C C   . THR E 1 69  ? -57.333  16.113  38.864  1.00 58.07  ? 276 THR E C   1 
ATOM   6375  O O   . THR E 1 69  ? -58.173  16.126  39.770  1.00 62.63  ? 276 THR E O   1 
ATOM   6376  C CB  . THR E 1 69  ? -58.263  17.999  37.529  1.00 53.85  ? 276 THR E CB  1 
ATOM   6377  O OG1 . THR E 1 69  ? -58.601  17.281  36.335  1.00 60.68  ? 276 THR E OG1 1 
ATOM   6378  C CG2 . THR E 1 69  ? -58.038  19.453  37.183  1.00 52.23  ? 276 THR E CG2 1 
ATOM   6379  N N   . LYS E 1 70  ? -56.685  15.007  38.495  1.00 59.61  ? 277 LYS E N   1 
ATOM   6380  C CA  . LYS E 1 70  ? -57.124  13.701  38.969  1.00 60.95  ? 277 LYS E CA  1 
ATOM   6381  C C   . LYS E 1 70  ? -57.220  13.657  40.487  1.00 60.29  ? 277 LYS E C   1 
ATOM   6382  O O   . LYS E 1 70  ? -58.087  12.964  41.029  1.00 69.66  ? 277 LYS E O   1 
ATOM   6383  C CB  . LYS E 1 70  ? -56.195  12.602  38.436  1.00 52.15  ? 277 LYS E CB  1 
ATOM   6384  N N   . LYS E 1 71  ? -56.380  14.421  41.193  1.00 60.88  ? 278 LYS E N   1 
ATOM   6385  C CA  . LYS E 1 71  ? -56.474  14.448  42.652  1.00 63.83  ? 278 LYS E CA  1 
ATOM   6386  C C   . LYS E 1 71  ? -57.733  15.181  43.118  1.00 68.25  ? 278 LYS E C   1 
ATOM   6387  O O   . LYS E 1 71  ? -58.286  14.854  44.176  1.00 66.05  ? 278 LYS E O   1 
ATOM   6388  C CB  . LYS E 1 71  ? -55.212  15.079  43.253  1.00 64.49  ? 278 LYS E CB  1 
ATOM   6389  N N   . LEU E 1 72  ? -58.231  16.156  42.360  1.00 69.29  ? 279 LEU E N   1 
ATOM   6390  C CA  . LEU E 1 72  ? -59.455  16.910  42.751  1.00 66.91  ? 279 LEU E CA  1 
ATOM   6391  C C   . LEU E 1 72  ? -60.701  16.038  42.573  1.00 65.79  ? 279 LEU E C   1 
ATOM   6392  O O   . LEU E 1 72  ? -61.571  16.083  43.438  1.00 61.91  ? 279 LEU E O   1 
ATOM   6393  C CB  . LEU E 1 72  ? -59.553  18.185  41.912  1.00 64.46  ? 279 LEU E CB  1 
ATOM   6394  C CG  . LEU E 1 72  ? -60.702  19.130  42.253  1.00 68.82  ? 279 LEU E CG  1 
ATOM   6395  C CD1 . LEU E 1 72  ? -60.494  19.798  43.601  1.00 70.30  ? 279 LEU E CD1 1 
ATOM   6396  C CD2 . LEU E 1 72  ? -60.873  20.177  41.171  1.00 60.72  ? 279 LEU E CD2 1 
ATOM   6397  N N   . THR E 1 73  ? -60.769  15.264  41.494  1.00 63.58  ? 280 THR E N   1 
ATOM   6398  C CA  . THR E 1 73  ? -61.935  14.378  41.249  1.00 62.85  ? 280 THR E CA  1 
ATOM   6399  C C   . THR E 1 73  ? -61.955  13.247  42.273  1.00 65.86  ? 280 THR E C   1 
ATOM   6400  O O   . THR E 1 73  ? -63.051  12.804  42.617  1.00 65.65  ? 280 THR E O   1 
ATOM   6401  C CB  . THR E 1 73  ? -61.945  13.815  39.828  1.00 65.15  ? 280 THR E CB  1 
ATOM   6402  O OG1 . THR E 1 73  ? -60.633  13.360  39.499  1.00 65.95  ? 280 THR E OG1 1 
ATOM   6403  C CG2 . THR E 1 73  ? -62.430  14.831  38.819  1.00 64.36  ? 280 THR E CG2 1 
ATOM   6404  N N   . LYS E 1 74  ? -60.789  12.796  42.727  1.00 66.40  ? 281 LYS E N   1 
ATOM   6405  C CA  . LYS E 1 74  ? -60.744  11.767  43.790  1.00 67.07  ? 281 LYS E CA  1 
ATOM   6406  C C   . LYS E 1 74  ? -61.259  12.388  45.082  1.00 68.88  ? 281 LYS E C   1 
ATOM   6407  O O   . LYS E 1 74  ? -61.991  11.706  45.804  1.00 63.40  ? 281 LYS E O   1 
ATOM   6408  C CB  . LYS E 1 74  ? -59.311  11.277  43.981  1.00 63.03  ? 281 LYS E CB  1 
ATOM   6409  N N   . SER E 1 75  ? -60.859  13.629  45.353  1.00 70.59  ? 282 SER E N   1 
ATOM   6410  C CA  . SER E 1 75  ? -61.318  14.344  46.567  1.00 69.78  ? 282 SER E CA  1 
ATOM   6411  C C   . SER E 1 75  ? -62.838  14.485  46.534  1.00 65.29  ? 282 SER E C   1 
ATOM   6412  O O   . SER E 1 75  ? -63.427  14.638  47.611  1.00 59.33  ? 282 SER E O   1 
ATOM   6413  C CB  . SER E 1 75  ? -60.617  15.663  46.685  1.00 73.61  ? 282 SER E CB  1 
ATOM   6414  O OG  . SER E 1 75  ? -61.310  16.690  45.998  1.00 77.54  ? 282 SER E OG  1 
ATOM   6415  N N   . PHE E 1 76  ? -63.439  14.452  45.343  1.00 66.47  ? 283 PHE E N   1 
ATOM   6416  C CA  . PHE E 1 76  ? -64.894  14.470  45.252  1.00 61.69  ? 283 PHE E CA  1 
ATOM   6417  C C   . PHE E 1 76  ? -65.523  13.161  45.684  1.00 59.01  ? 283 PHE E C   1 
ATOM   6418  O O   . PHE E 1 76  ? -66.743  13.121  45.844  1.00 54.23  ? 283 PHE E O   1 
ATOM   6419  C CB  . PHE E 1 76  ? -65.376  14.751  43.828  1.00 60.94  ? 283 PHE E CB  1 
ATOM   6420  C CG  . PHE E 1 76  ? -64.999  16.090  43.312  1.00 63.14  ? 283 PHE E CG  1 
ATOM   6421  C CD1 . PHE E 1 76  ? -64.538  17.072  44.171  1.00 59.04  ? 283 PHE E CD1 1 
ATOM   6422  C CD2 . PHE E 1 76  ? -65.098  16.366  41.951  1.00 65.96  ? 283 PHE E CD2 1 
ATOM   6423  C CE1 . PHE E 1 76  ? -64.169  18.303  43.703  1.00 63.41  ? 283 PHE E CE1 1 
ATOM   6424  C CE2 . PHE E 1 76  ? -64.731  17.595  41.464  1.00 64.21  ? 283 PHE E CE2 1 
ATOM   6425  C CZ  . PHE E 1 76  ? -64.264  18.572  42.345  1.00 67.83  ? 283 PHE E CZ  1 
ATOM   6426  N N   . GLY E 1 77  ? -64.738  12.101  45.864  1.00 60.38  ? 284 GLY E N   1 
ATOM   6427  C CA  . GLY E 1 77  ? -65.302  10.787  46.067  1.00 59.21  ? 284 GLY E CA  1 
ATOM   6428  C C   . GLY E 1 77  ? -65.580  10.027  44.800  1.00 58.56  ? 284 GLY E C   1 
ATOM   6429  O O   . GLY E 1 77  ? -66.241  8.987   44.857  1.00 59.56  ? 284 GLY E O   1 
ATOM   6430  N N   . TRP E 1 78  ? -65.080  10.498  43.661  1.00 59.19  ? 285 TRP E N   1 
ATOM   6431  C CA  . TRP E 1 78  ? -65.472  9.915   42.393  1.00 59.75  ? 285 TRP E CA  1 
ATOM   6432  C C   . TRP E 1 78  ? -64.670  8.656   42.087  1.00 58.03  ? 285 TRP E C   1 
ATOM   6433  O O   . TRP E 1 78  ? -63.618  8.396   42.670  1.00 65.84  ? 285 TRP E O   1 
ATOM   6434  C CB  . TRP E 1 78  ? -65.331  10.938  41.274  1.00 57.52  ? 285 TRP E CB  1 
ATOM   6435  C CG  . TRP E 1 78  ? -66.474  11.899  41.256  1.00 66.42  ? 285 TRP E CG  1 
ATOM   6436  C CD1 . TRP E 1 78  ? -67.584  11.873  42.067  1.00 67.04  ? 285 TRP E CD1 1 
ATOM   6437  C CD2 . TRP E 1 78  ? -66.628  13.046  40.407  1.00 66.84  ? 285 TRP E CD2 1 
ATOM   6438  N NE1 . TRP E 1 78  ? -68.415  12.930  41.769  1.00 66.68  ? 285 TRP E NE1 1 
ATOM   6439  C CE2 . TRP E 1 78  ? -67.851  13.665  40.757  1.00 66.14  ? 285 TRP E CE2 1 
ATOM   6440  C CE3 . TRP E 1 78  ? -65.853  13.610  39.388  1.00 61.45  ? 285 TRP E CE3 1 
ATOM   6441  C CZ2 . TRP E 1 78  ? -68.318  14.805  40.114  1.00 66.20  ? 285 TRP E CZ2 1 
ATOM   6442  C CZ3 . TRP E 1 78  ? -66.315  14.747  38.762  1.00 60.97  ? 285 TRP E CZ3 1 
ATOM   6443  C CH2 . TRP E 1 78  ? -67.538  15.332  39.122  1.00 63.32  ? 285 TRP E CH2 1 
ATOM   6444  N N   . GLU E 1 79  ? -65.216  7.845   41.190  1.00 56.11  ? 286 GLU E N   1 
ATOM   6445  C CA  . GLU E 1 79  ? -64.530  6.678   40.663  1.00 63.35  ? 286 GLU E CA  1 
ATOM   6446  C C   . GLU E 1 79  ? -64.027  6.996   39.260  1.00 70.23  ? 286 GLU E C   1 
ATOM   6447  O O   . GLU E 1 79  ? -64.406  8.007   38.646  1.00 64.49  ? 286 GLU E O   1 
ATOM   6448  C CB  . GLU E 1 79  ? -65.448  5.443   40.650  1.00 70.03  ? 286 GLU E CB  1 
ATOM   6449  C CG  . GLU E 1 79  ? -65.463  4.639   41.949  1.00 73.40  ? 286 GLU E CG  1 
ATOM   6450  N N   . THR E 1 80  ? -63.138  6.128   38.761  1.00 67.33  ? 287 THR E N   1 
ATOM   6451  C CA  . THR E 1 80  ? -62.491  6.406   37.481  1.00 64.40  ? 287 THR E CA  1 
ATOM   6452  C C   . THR E 1 80  ? -63.525  6.684   36.393  1.00 58.87  ? 287 THR E C   1 
ATOM   6453  O O   . THR E 1 80  ? -63.380  7.628   35.614  1.00 60.51  ? 287 THR E O   1 
ATOM   6454  C CB  . THR E 1 80  ? -61.570  5.240   37.109  1.00 69.28  ? 287 THR E CB  1 
ATOM   6455  O OG1 . THR E 1 80  ? -62.337  4.142   36.602  1.00 66.50  ? 287 THR E OG1 1 
ATOM   6456  C CG2 . THR E 1 80  ? -60.794  4.770   38.337  1.00 70.60  ? 287 THR E CG2 1 
ATOM   6457  N N   . LEU E 1 81  ? -64.618  5.925   36.385  1.00 62.78  ? 288 LEU E N   1 
ATOM   6458  C CA  . LEU E 1 81  ? -65.662  6.101   35.383  1.00 60.02  ? 288 LEU E CA  1 
ATOM   6459  C C   . LEU E 1 81  ? -66.321  7.478   35.444  1.00 60.88  ? 288 LEU E C   1 
ATOM   6460  O O   . LEU E 1 81  ? -66.818  7.944   34.414  1.00 58.42  ? 288 LEU E O   1 
ATOM   6461  C CB  . LEU E 1 81  ? -66.705  4.989   35.528  1.00 54.31  ? 288 LEU E CB  1 
ATOM   6462  C CG  . LEU E 1 81  ? -68.076  5.168   34.886  1.00 60.90  ? 288 LEU E CG  1 
ATOM   6463  C CD1 . LEU E 1 81  ? -67.960  4.859   33.411  1.00 70.70  ? 288 LEU E CD1 1 
ATOM   6464  C CD2 . LEU E 1 81  ? -69.084  4.253   35.524  1.00 56.84  ? 288 LEU E CD2 1 
ATOM   6465  N N   . ASP E 1 82  ? -66.295  8.163   36.597  1.00 57.85  ? 289 ASP E N   1 
ATOM   6466  C CA  . ASP E 1 82  ? -66.975  9.456   36.738  1.00 54.22  ? 289 ASP E CA  1 
ATOM   6467  C C   . ASP E 1 82  ? -66.329  10.572  35.929  1.00 57.92  ? 289 ASP E C   1 
ATOM   6468  O O   . ASP E 1 82  ? -66.986  11.578  35.648  1.00 60.77  ? 289 ASP E O   1 
ATOM   6469  C CB  . ASP E 1 82  ? -66.995  9.887   38.195  1.00 59.79  ? 289 ASP E CB  1 
ATOM   6470  C CG  . ASP E 1 82  ? -67.910  9.069   39.017  1.00 61.31  ? 289 ASP E CG  1 
ATOM   6471  O OD1 . ASP E 1 82  ? -69.087  8.952   38.615  1.00 68.75  ? 289 ASP E OD1 1 
ATOM   6472  O OD2 . ASP E 1 82  ? -67.459  8.553   40.063  1.00 63.24  ? 289 ASP E OD2 1 
ATOM   6473  N N   . SER E 1 83  ? -65.050  10.440  35.590  1.00 58.66  ? 290 SER E N   1 
ATOM   6474  C CA  . SER E 1 83  ? -64.356  11.473  34.843  1.00 57.36  ? 290 SER E CA  1 
ATOM   6475  C C   . SER E 1 83  ? -64.810  11.569  33.407  1.00 58.32  ? 290 SER E C   1 
ATOM   6476  O O   . SER E 1 83  ? -64.275  12.404  32.678  1.00 63.56  ? 290 SER E O   1 
ATOM   6477  C CB  . SER E 1 83  ? -62.842  11.260  34.915  1.00 63.48  ? 290 SER E CB  1 
ATOM   6478  O OG  . SER E 1 83  ? -62.451  10.946  36.247  1.00 62.25  ? 290 SER E OG  1 
ATOM   6479  N N   . PHE E 1 84  ? -65.748  10.738  32.967  1.00 55.93  ? 291 PHE E N   1 
ATOM   6480  C CA  . PHE E 1 84  ? -66.183  10.727  31.579  1.00 53.46  ? 291 PHE E CA  1 
ATOM   6481  C C   . PHE E 1 84  ? -67.620  11.176  31.427  1.00 56.15  ? 291 PHE E C   1 
ATOM   6482  O O   . PHE E 1 84  ? -68.211  10.968  30.361  1.00 55.03  ? 291 PHE E O   1 
ATOM   6483  C CB  . PHE E 1 84  ? -65.990  9.339   30.966  1.00 54.44  ? 291 PHE E CB  1 
ATOM   6484  C CG  . PHE E 1 84  ? -64.545  9.001   30.683  1.00 55.44  ? 291 PHE E CG  1 
ATOM   6485  C CD1 . PHE E 1 84  ? -63.952  9.380   29.488  1.00 55.80  ? 291 PHE E CD1 1 
ATOM   6486  C CD2 . PHE E 1 84  ? -63.781  8.305   31.615  1.00 52.63  ? 291 PHE E CD2 1 
ATOM   6487  C CE1 . PHE E 1 84  ? -62.637  9.067   29.230  1.00 59.62  ? 291 PHE E CE1 1 
ATOM   6488  C CE2 . PHE E 1 84  ? -62.470  8.002   31.367  1.00 49.25  ? 291 PHE E CE2 1 
ATOM   6489  C CZ  . PHE E 1 84  ? -61.896  8.374   30.175  1.00 55.80  ? 291 PHE E CZ  1 
ATOM   6490  N N   . MET E 1 85  ? -68.198  11.788  32.461  1.00 57.06  ? 292 MET E N   1 
ATOM   6491  C CA  . MET E 1 85  ? -69.566  12.286  32.397  1.00 57.35  ? 292 MET E CA  1 
ATOM   6492  C C   . MET E 1 85  ? -69.565  13.804  32.280  1.00 58.01  ? 292 MET E C   1 
ATOM   6493  O O   . MET E 1 85  ? -69.043  14.501  33.159  1.00 54.47  ? 292 MET E O   1 
ATOM   6494  C CB  . MET E 1 85  ? -70.388  11.839  33.601  1.00 57.64  ? 292 MET E CB  1 
ATOM   6495  C CG  . MET E 1 85  ? -71.861  12.231  33.440  1.00 63.16  ? 292 MET E CG  1 
ATOM   6496  S SD  . MET E 1 85  ? -72.969  11.447  34.627  1.00 81.44  ? 292 MET E SD  1 
ATOM   6497  C CE  . MET E 1 85  ? -74.402  11.077  33.589  1.00 72.22  ? 292 MET E CE  1 
ATOM   6498  N N   . GLN E 1 86  ? -70.173  14.296  31.201  1.00 58.28  ? 293 GLN E N   1 
ATOM   6499  C CA  . GLN E 1 86  ? -70.288  15.723  30.937  1.00 56.56  ? 293 GLN E CA  1 
ATOM   6500  C C   . GLN E 1 86  ? -71.269  16.375  31.900  1.00 58.83  ? 293 GLN E C   1 
ATOM   6501  O O   . GLN E 1 86  ? -72.315  15.800  32.221  1.00 60.22  ? 293 GLN E O   1 
ATOM   6502  C CB  . GLN E 1 86  ? -70.766  15.951  29.507  1.00 52.47  ? 293 GLN E CB  1 
ATOM   6503  C CG  . GLN E 1 86  ? -69.940  15.273  28.448  1.00 54.26  ? 293 GLN E CG  1 
ATOM   6504  C CD  . GLN E 1 86  ? -70.212  15.856  27.094  1.00 60.39  ? 293 GLN E CD  1 
ATOM   6505  O OE1 . GLN E 1 86  ? -71.215  16.540  26.908  1.00 60.29  ? 293 GLN E OE1 1 
ATOM   6506  N NE2 . GLN E 1 86  ? -69.327  15.591  26.134  1.00 59.82  ? 293 GLN E NE2 1 
ATOM   6507  N N   . HIS E 1 87  ? -70.953  17.597  32.337  1.00 55.68  ? 294 HIS E N   1 
ATOM   6508  C CA  . HIS E 1 87  ? -71.712  18.210  33.418  1.00 55.57  ? 294 HIS E CA  1 
ATOM   6509  C C   . HIS E 1 87  ? -72.019  19.675  33.117  1.00 58.19  ? 294 HIS E C   1 
ATOM   6510  O O   . HIS E 1 87  ? -71.534  20.258  32.142  1.00 58.32  ? 294 HIS E O   1 
ATOM   6511  C CB  . HIS E 1 87  ? -70.972  18.070  34.751  1.00 52.32  ? 294 HIS E CB  1 
ATOM   6512  C CG  . HIS E 1 87  ? -71.170  16.740  35.403  1.00 51.97  ? 294 HIS E CG  1 
ATOM   6513  N ND1 . HIS E 1 87  ? -72.369  16.364  35.968  1.00 53.41  ? 294 HIS E ND1 1 
ATOM   6514  C CD2 . HIS E 1 87  ? -70.338  15.679  35.546  1.00 51.96  ? 294 HIS E CD2 1 
ATOM   6515  C CE1 . HIS E 1 87  ? -72.262  15.139  36.452  1.00 51.86  ? 294 HIS E CE1 1 
ATOM   6516  N NE2 . HIS E 1 87  ? -71.041  14.698  36.208  1.00 50.12  ? 294 HIS E NE2 1 
ATOM   6517  N N   . ASP E 1 88  ? -72.879  20.240  33.967  1.00 56.04  ? 295 ASP E N   1 
ATOM   6518  C CA  . ASP E 1 88  ? -73.287  21.638  33.925  1.00 49.32  ? 295 ASP E CA  1 
ATOM   6519  C C   . ASP E 1 88  ? -72.351  22.435  34.828  1.00 51.67  ? 295 ASP E C   1 
ATOM   6520  O O   . ASP E 1 88  ? -72.087  22.024  35.964  1.00 56.09  ? 295 ASP E O   1 
ATOM   6521  C CB  . ASP E 1 88  ? -74.745  21.754  34.386  1.00 45.60  ? 295 ASP E CB  1 
ATOM   6522  C CG  . ASP E 1 88  ? -75.242  23.184  34.447  1.00 53.46  ? 295 ASP E CG  1 
ATOM   6523  O OD1 . ASP E 1 88  ? -74.942  23.890  35.437  1.00 53.87  ? 295 ASP E OD1 1 
ATOM   6524  O OD2 . ASP E 1 88  ? -75.960  23.602  33.514  1.00 50.61  ? 295 ASP E OD2 1 
ATOM   6525  N N   . VAL E 1 89  ? -71.838  23.567  34.329  1.00 54.42  ? 296 VAL E N   1 
ATOM   6526  C CA  . VAL E 1 89  ? -70.807  24.286  35.082  1.00 50.41  ? 296 VAL E CA  1 
ATOM   6527  C C   . VAL E 1 89  ? -71.404  25.038  36.275  1.00 53.82  ? 296 VAL E C   1 
ATOM   6528  O O   . VAL E 1 89  ? -70.755  25.165  37.323  1.00 52.34  ? 296 VAL E O   1 
ATOM   6529  C CB  . VAL E 1 89  ? -69.996  25.227  34.165  1.00 51.77  ? 296 VAL E CB  1 
ATOM   6530  C CG1 . VAL E 1 89  ? -70.851  26.362  33.592  1.00 47.96  ? 296 VAL E CG1 1 
ATOM   6531  C CG2 . VAL E 1 89  ? -68.783  25.778  34.904  1.00 48.77  ? 296 VAL E CG2 1 
ATOM   6532  N N   . GLN E 1 90  ? -72.640  25.520  36.179  1.00 49.37  ? 297 GLN E N   1 
ATOM   6533  C CA  . GLN E 1 90  ? -73.186  26.208  37.371  1.00 53.07  ? 297 GLN E CA  1 
ATOM   6534  C C   . GLN E 1 90  ? -73.485  25.170  38.446  1.00 50.89  ? 297 GLN E C   1 
ATOM   6535  O O   . GLN E 1 90  ? -73.333  25.488  39.619  1.00 50.49  ? 297 GLN E O   1 
ATOM   6536  C CB  . GLN E 1 90  ? -74.432  27.023  37.038  1.00 52.93  ? 297 GLN E CB  1 
ATOM   6537  C CG  . GLN E 1 90  ? -74.875  27.935  38.172  1.00 47.17  ? 297 GLN E CG  1 
ATOM   6538  C CD  . GLN E 1 90  ? -76.190  27.474  38.746  1.00 49.30  ? 297 GLN E CD  1 
ATOM   6539  O OE1 . GLN E 1 90  ? -76.845  26.594  38.208  1.00 52.13  ? 297 GLN E OE1 1 
ATOM   6540  N NE2 . GLN E 1 90  ? -76.631  28.112  39.811  1.00 54.98  ? 297 GLN E NE2 1 
ATOM   6541  N N   . GLU E 1 91  ? -73.860  23.964  38.043  1.00 49.45  ? 298 GLU E N   1 
ATOM   6542  C CA  . GLU E 1 91  ? -74.084  22.928  39.047  1.00 50.23  ? 298 GLU E CA  1 
ATOM   6543  C C   . GLU E 1 91  ? -72.828  22.704  39.881  1.00 49.24  ? 298 GLU E C   1 
ATOM   6544  O O   . GLU E 1 91  ? -72.857  22.839  41.107  1.00 48.47  ? 298 GLU E O   1 
ATOM   6545  C CB  . GLU E 1 91  ? -74.538  21.638  38.370  1.00 48.65  ? 298 GLU E CB  1 
ATOM   6546  C CG  . GLU E 1 91  ? -75.083  20.576  39.278  1.00 43.66  ? 298 GLU E CG  1 
ATOM   6547  C CD  . GLU E 1 91  ? -75.832  19.491  38.501  1.00 51.53  ? 298 GLU E CD  1 
ATOM   6548  O OE1 . GLU E 1 91  ? -76.803  18.947  39.060  1.00 50.52  ? 298 GLU E OE1 1 
ATOM   6549  O OE2 . GLU E 1 91  ? -75.460  19.186  37.335  1.00 50.30  ? 298 GLU E OE2 1 
ATOM   6550  N N   . LEU E 1 92  ? -71.706  22.388  39.241  1.00 45.00  ? 299 LEU E N   1 
ATOM   6551  C CA  . LEU E 1 92  ? -70.430  22.216  39.982  1.00 42.18  ? 299 LEU E CA  1 
ATOM   6552  C C   . LEU E 1 92  ? -70.166  23.437  40.852  1.00 45.25  ? 299 LEU E C   1 
ATOM   6553  O O   . LEU E 1 92  ? -69.858  23.251  42.007  1.00 48.37  ? 299 LEU E O   1 
ATOM   6554  C CB  . LEU E 1 92  ? -69.276  22.027  38.997  1.00 46.79  ? 299 LEU E CB  1 
ATOM   6555  C CG  . LEU E 1 92  ? -67.880  22.002  39.612  1.00 49.44  ? 299 LEU E CG  1 
ATOM   6556  C CD1 . LEU E 1 92  ? -67.618  20.684  40.319  1.00 44.31  ? 299 LEU E CD1 1 
ATOM   6557  C CD2 . LEU E 1 92  ? -66.828  22.254  38.553  1.00 49.48  ? 299 LEU E CD2 1 
ATOM   6558  N N   . CYS E 1 93  ? -70.271  24.634  40.293  1.00 52.51  ? 300 CYS E N   1 
ATOM   6559  C CA  . CYS E 1 93  ? -69.961  25.878  41.054  1.00 46.54  ? 300 CYS E CA  1 
ATOM   6560  C C   . CYS E 1 93  ? -70.746  25.910  42.355  1.00 45.75  ? 300 CYS E C   1 
ATOM   6561  O O   . CYS E 1 93  ? -70.160  26.232  43.380  1.00 47.40  ? 300 CYS E O   1 
ATOM   6562  C CB  . CYS E 1 93  ? -70.323  27.128  40.264  1.00 46.89  ? 300 CYS E CB  1 
ATOM   6563  S SG  . CYS E 1 93  ? -69.912  28.681  41.094  1.00 51.06  ? 300 CYS E SG  1 
ATOM   6564  N N   . ARG E 1 94  ? -72.034  25.606  42.288  1.00 48.97  ? 301 ARG E N   1 
ATOM   6565  C CA  . ARG E 1 94  ? -72.856  25.684  43.514  1.00 49.93  ? 301 ARG E CA  1 
ATOM   6566  C C   . ARG E 1 94  ? -72.405  24.606  44.498  1.00 46.56  ? 301 ARG E C   1 
ATOM   6567  O O   . ARG E 1 94  ? -72.297  24.920  45.678  1.00 52.20  ? 301 ARG E O   1 
ATOM   6568  C CB  . ARG E 1 94  ? -74.342  25.583  43.154  1.00 42.25  ? 301 ARG E CB  1 
ATOM   6569  C CG  . ARG E 1 94  ? -74.850  26.719  42.284  1.00 47.19  ? 301 ARG E CG  1 
ATOM   6570  C CD  . ARG E 1 94  ? -75.317  27.961  43.017  1.00 48.13  ? 301 ARG E CD  1 
ATOM   6571  N NE  . ARG E 1 94  ? -74.298  28.641  43.803  1.00 50.58  ? 301 ARG E NE  1 
ATOM   6572  C CZ  . ARG E 1 94  ? -73.348  29.431  43.319  1.00 51.07  ? 301 ARG E CZ  1 
ATOM   6573  N NH1 . ARG E 1 94  ? -73.265  29.672  42.023  1.00 48.03  ? 301 ARG E NH1 1 
ATOM   6574  N NH2 . ARG E 1 94  ? -72.471  29.974  44.139  1.00 52.73  ? 301 ARG E NH2 1 
ATOM   6575  N N   . VAL E 1 95  ? -72.157  23.390  44.017  1.00 38.60  ? 302 VAL E N   1 
ATOM   6576  C CA  . VAL E 1 95  ? -71.750  22.323  44.919  1.00 44.21  ? 302 VAL E CA  1 
ATOM   6577  C C   . VAL E 1 95  ? -70.318  22.547  45.410  1.00 45.33  ? 302 VAL E C   1 
ATOM   6578  O O   . VAL E 1 95  ? -70.004  22.269  46.570  1.00 49.05  ? 302 VAL E O   1 
ATOM   6579  C CB  . VAL E 1 95  ? -71.915  20.947  44.236  1.00 48.75  ? 302 VAL E CB  1 
ATOM   6580  C CG1 . VAL E 1 95  ? -71.715  19.841  45.225  1.00 35.96  ? 302 VAL E CG1 1 
ATOM   6581  C CG2 . VAL E 1 95  ? -73.276  20.826  43.559  1.00 39.55  ? 302 VAL E CG2 1 
ATOM   6582  N N   . LEU E 1 96  ? -69.431  23.073  44.557  1.00 46.10  ? 303 LEU E N   1 
ATOM   6583  C CA  . LEU E 1 96  ? -68.024  23.200  44.952  1.00 52.87  ? 303 LEU E CA  1 
ATOM   6584  C C   . LEU E 1 96  ? -67.760  24.415  45.842  1.00 54.25  ? 303 LEU E C   1 
ATOM   6585  O O   . LEU E 1 96  ? -66.997  24.312  46.808  1.00 53.90  ? 303 LEU E O   1 
ATOM   6586  C CB  . LEU E 1 96  ? -67.107  23.271  43.733  1.00 51.66  ? 303 LEU E CB  1 
ATOM   6587  C CG  . LEU E 1 96  ? -65.633  23.319  44.142  1.00 49.62  ? 303 LEU E CG  1 
ATOM   6588  C CD1 . LEU E 1 96  ? -64.999  21.936  44.109  1.00 60.82  ? 303 LEU E CD1 1 
ATOM   6589  C CD2 . LEU E 1 96  ? -64.885  24.266  43.242  1.00 50.59  ? 303 LEU E CD2 1 
ATOM   6590  N N   . LEU E 1 97  ? -68.358  25.571  45.538  1.00 50.72  ? 304 LEU E N   1 
ATOM   6591  C CA  . LEU E 1 97  ? -68.217  26.714  46.437  1.00 50.53  ? 304 LEU E CA  1 
ATOM   6592  C C   . LEU E 1 97  ? -68.841  26.433  47.800  1.00 49.57  ? 304 LEU E C   1 
ATOM   6593  O O   . LEU E 1 97  ? -68.350  26.915  48.822  1.00 52.02  ? 304 LEU E O   1 
ATOM   6594  C CB  . LEU E 1 97  ? -68.852  27.963  45.826  1.00 54.49  ? 304 LEU E CB  1 
ATOM   6595  C CG  . LEU E 1 97  ? -68.091  28.766  44.766  1.00 52.76  ? 304 LEU E CG  1 
ATOM   6596  C CD1 . LEU E 1 97  ? -68.724  30.131  44.586  1.00 46.16  ? 304 LEU E CD1 1 
ATOM   6597  C CD2 . LEU E 1 97  ? -66.643  28.904  45.144  1.00 51.54  ? 304 LEU E CD2 1 
ATOM   6598  N N   . ASP E 1 98  ? -69.939  25.679  47.835  1.00 51.91  ? 305 ASP E N   1 
ATOM   6599  C CA  . ASP E 1 98  ? -70.569  25.353  49.112  1.00 53.92  ? 305 ASP E CA  1 
ATOM   6600  C C   . ASP E 1 98  ? -69.651  24.492  49.963  1.00 58.27  ? 305 ASP E C   1 
ATOM   6601  O O   . ASP E 1 98  ? -69.501  24.723  51.169  1.00 57.36  ? 305 ASP E O   1 
ATOM   6602  C CB  . ASP E 1 98  ? -71.890  24.626  48.877  1.00 54.92  ? 305 ASP E CB  1 
ATOM   6603  C CG  . ASP E 1 98  ? -72.651  24.375  50.165  1.00 58.90  ? 305 ASP E CG  1 
ATOM   6604  O OD1 . ASP E 1 98  ? -73.086  25.362  50.803  1.00 59.28  ? 305 ASP E OD1 1 
ATOM   6605  O OD2 . ASP E 1 98  ? -72.812  23.197  50.538  1.00 59.54  ? 305 ASP E OD2 1 
ATOM   6606  N N   . ASN E 1 99  ? -69.055  23.478  49.345  1.00 56.73  ? 306 ASN E N   1 
ATOM   6607  C CA  . ASN E 1 99  ? -68.007  22.685  49.966  1.00 61.35  ? 306 ASN E CA  1 
ATOM   6608  C C   . ASN E 1 99  ? -66.910  23.566  50.563  1.00 61.94  ? 306 ASN E C   1 
ATOM   6609  O O   . ASN E 1 99  ? -66.606  23.484  51.760  1.00 60.90  ? 306 ASN E O   1 
ATOM   6610  C CB  . ASN E 1 99  ? -67.443  21.737  48.910  1.00 61.33  ? 306 ASN E CB  1 
ATOM   6611  C CG  . ASN E 1 99  ? -66.446  20.774  49.467  1.00 62.79  ? 306 ASN E CG  1 
ATOM   6612  O OD1 . ASN E 1 99  ? -65.316  21.148  49.772  1.00 69.33  ? 306 ASN E OD1 1 
ATOM   6613  N ND2 . ASN E 1 99  ? -66.852  19.522  49.609  1.00 63.14  ? 306 ASN E ND2 1 
ATOM   6614  N N   . VAL E 1 100 ? -66.301  24.423  49.739  1.00 51.30  ? 307 VAL E N   1 
ATOM   6615  C CA  . VAL E 1 100 ? -65.218  25.246  50.250  1.00 53.25  ? 307 VAL E CA  1 
ATOM   6616  C C   . VAL E 1 100 ? -65.721  26.165  51.353  1.00 57.95  ? 307 VAL E C   1 
ATOM   6617  O O   . VAL E 1 100 ? -65.084  26.291  52.404  1.00 62.61  ? 307 VAL E O   1 
ATOM   6618  C CB  . VAL E 1 100 ? -64.538  26.028  49.117  1.00 48.74  ? 307 VAL E CB  1 
ATOM   6619  C CG1 . VAL E 1 100 ? -63.603  27.063  49.698  1.00 50.90  ? 307 VAL E CG1 1 
ATOM   6620  C CG2 . VAL E 1 100 ? -63.771  25.082  48.231  1.00 40.53  ? 307 VAL E CG2 1 
ATOM   6621  N N   . GLU E 1 101 ? -66.885  26.789  51.153  1.00 55.60  ? 308 GLU E N   1 
ATOM   6622  C CA  . GLU E 1 101 ? -67.396  27.751  52.134  1.00 55.32  ? 308 GLU E CA  1 
ATOM   6623  C C   . GLU E 1 101 ? -67.504  27.130  53.515  1.00 55.67  ? 308 GLU E C   1 
ATOM   6624  O O   . GLU E 1 101 ? -67.094  27.728  54.509  1.00 59.47  ? 308 GLU E O   1 
ATOM   6625  C CB  . GLU E 1 101 ? -68.762  28.299  51.703  1.00 54.85  ? 308 GLU E CB  1 
ATOM   6626  C CG  . GLU E 1 101 ? -69.421  29.219  52.758  1.00 56.04  ? 308 GLU E CG  1 
ATOM   6627  C CD  . GLU E 1 101 ? -70.763  29.852  52.312  1.00 60.62  ? 308 GLU E CD  1 
ATOM   6628  O OE1 . GLU E 1 101 ? -71.386  30.551  53.141  1.00 67.51  ? 308 GLU E OE1 1 
ATOM   6629  O OE2 . GLU E 1 101 ? -71.212  29.658  51.158  1.00 62.56  ? 308 GLU E OE2 1 
ATOM   6630  N N   . ASN E 1 102 ? -68.076  25.936  53.600  1.00 59.75  ? 309 ASN E N   1 
ATOM   6631  C CA  . ASN E 1 102 ? -68.207  25.301  54.901  1.00 64.93  ? 309 ASN E CA  1 
ATOM   6632  C C   . ASN E 1 102 ? -66.852  24.865  55.425  1.00 67.73  ? 309 ASN E C   1 
ATOM   6633  O O   . ASN E 1 102 ? -66.616  24.905  56.638  1.00 65.16  ? 309 ASN E O   1 
ATOM   6634  C CB  . ASN E 1 102 ? -69.163  24.105  54.818  1.00 71.24  ? 309 ASN E CB  1 
ATOM   6635  C CG  . ASN E 1 102 ? -70.628  24.517  54.908  1.00 75.89  ? 309 ASN E CG  1 
ATOM   6636  O OD1 . ASN E 1 102 ? -71.176  24.666  56.005  1.00 67.69  ? 309 ASN E OD1 1 
ATOM   6637  N ND2 . ASN E 1 102 ? -71.268  24.706  53.751  1.00 74.63  ? 309 ASN E ND2 1 
ATOM   6638  N N   . LYS E 1 103 ? -65.952  24.458  54.525  1.00 63.05  ? 310 LYS E N   1 
ATOM   6639  C CA  . LYS E 1 103 ? -64.618  24.055  54.944  1.00 63.29  ? 310 LYS E CA  1 
ATOM   6640  C C   . LYS E 1 103 ? -63.824  25.242  55.476  1.00 68.19  ? 310 LYS E C   1 
ATOM   6641  O O   . LYS E 1 103 ? -63.018  25.082  56.404  1.00 70.97  ? 310 LYS E O   1 
ATOM   6642  C CB  . LYS E 1 103 ? -63.887  23.378  53.783  1.00 66.22  ? 310 LYS E CB  1 
ATOM   6643  N N   . MET E 1 104 ? -64.060  26.438  54.924  1.00 63.70  ? 311 MET E N   1 
ATOM   6644  C CA  . MET E 1 104 ? -63.475  27.662  55.449  1.00 60.12  ? 311 MET E CA  1 
ATOM   6645  C C   . MET E 1 104 ? -64.069  28.065  56.796  1.00 62.73  ? 311 MET E C   1 
ATOM   6646  O O   . MET E 1 104 ? -63.496  28.927  57.470  1.00 65.52  ? 311 MET E O   1 
ATOM   6647  C CB  . MET E 1 104 ? -63.645  28.806  54.438  1.00 54.90  ? 311 MET E CB  1 
ATOM   6648  C CG  . MET E 1 104 ? -62.645  28.804  53.293  1.00 59.16  ? 311 MET E CG  1 
ATOM   6649  S SD  . MET E 1 104 ? -62.627  30.398  52.433  1.00 63.84  ? 311 MET E SD  1 
ATOM   6650  C CE  . MET E 1 104 ? -61.643  30.021  50.992  1.00 59.51  ? 311 MET E CE  1 
ATOM   6651  N N   . LYS E 1 105 ? -65.189  27.479  57.208  1.00 61.25  ? 312 LYS E N   1 
ATOM   6652  C CA  . LYS E 1 105 ? -65.733  27.796  58.520  1.00 67.80  ? 312 LYS E CA  1 
ATOM   6653  C C   . LYS E 1 105 ? -64.784  27.289  59.608  1.00 71.39  ? 312 LYS E C   1 
ATOM   6654  O O   . LYS E 1 105 ? -64.150  26.240  59.458  1.00 73.27  ? 312 LYS E O   1 
ATOM   6655  C CB  . LYS E 1 105 ? -67.135  27.192  58.677  1.00 63.57  ? 312 LYS E CB  1 
ATOM   6656  N N   . GLY E 1 106 ? -64.659  28.062  60.694  1.00 69.99  ? 313 GLY E N   1 
ATOM   6657  C CA  . GLY E 1 106 ? -63.745  27.755  61.777  1.00 69.89  ? 313 GLY E CA  1 
ATOM   6658  C C   . GLY E 1 106 ? -62.297  28.142  61.545  1.00 69.83  ? 313 GLY E C   1 
ATOM   6659  O O   . GLY E 1 106 ? -61.461  27.881  62.416  1.00 71.18  ? 313 GLY E O   1 
ATOM   6660  N N   . THR E 1 107 ? -61.975  28.761  60.417  1.00 67.96  ? 314 THR E N   1 
ATOM   6661  C CA  . THR E 1 107 ? -60.606  29.068  60.024  1.00 69.21  ? 314 THR E CA  1 
ATOM   6662  C C   . THR E 1 107 ? -60.418  30.576  59.962  1.00 70.19  ? 314 THR E C   1 
ATOM   6663  O O   . THR E 1 107 ? -61.364  31.351  60.109  1.00 69.47  ? 314 THR E O   1 
ATOM   6664  C CB  . THR E 1 107 ? -60.254  28.458  58.657  1.00 69.98  ? 314 THR E CB  1 
ATOM   6665  O OG1 . THR E 1 107 ? -60.626  29.372  57.610  1.00 62.23  ? 314 THR E OG1 1 
ATOM   6666  C CG2 . THR E 1 107 ? -60.957  27.138  58.438  1.00 61.13  ? 314 THR E CG2 1 
ATOM   6667  N N   . CYS E 1 108 ? -59.178  30.984  59.692  1.00 69.79  ? 315 CYS E N   1 
ATOM   6668  C CA  . CYS E 1 108 ? -58.861  32.401  59.613  1.00 67.15  ? 315 CYS E CA  1 
ATOM   6669  C C   . CYS E 1 108 ? -59.515  33.088  58.416  1.00 69.19  ? 315 CYS E C   1 
ATOM   6670  O O   . CYS E 1 108 ? -59.548  34.322  58.372  1.00 67.82  ? 315 CYS E O   1 
ATOM   6671  C CB  . CYS E 1 108 ? -57.343  32.584  59.564  1.00 70.93  ? 315 CYS E CB  1 
ATOM   6672  S SG  . CYS E 1 108 ? -56.549  31.988  58.036  1.00 82.22  ? 315 CYS E SG  1 
ATOM   6673  N N   . VAL E 1 109 ? -60.022  32.281  57.477  1.00 71.86  ? 316 VAL E N   1 
ATOM   6674  C CA  . VAL E 1 109 ? -60.620  32.816  56.219  1.00 66.28  ? 316 VAL E CA  1 
ATOM   6675  C C   . VAL E 1 109 ? -62.106  32.453  56.135  1.00 63.62  ? 316 VAL E C   1 
ATOM   6676  O O   . VAL E 1 109 ? -62.636  32.478  55.036  1.00 58.96  ? 316 VAL E O   1 
ATOM   6677  C CB  . VAL E 1 109 ? -59.829  32.358  54.976  1.00 64.11  ? 316 VAL E CB  1 
ATOM   6678  C CG1 . VAL E 1 109 ? -58.614  33.234  54.733  1.00 69.54  ? 316 VAL E CG1 1 
ATOM   6679  C CG2 . VAL E 1 109 ? -59.425  30.895  55.035  1.00 62.67  ? 316 VAL E CG2 1 
ATOM   6680  N N   . GLU E 1 110 ? -62.754  32.088  57.240  1.00 62.46  ? 317 GLU E N   1 
ATOM   6681  C CA  . GLU E 1 110 ? -64.194  31.923  57.240  1.00 61.48  ? 317 GLU E CA  1 
ATOM   6682  C C   . GLU E 1 110 ? -64.855  33.167  56.661  1.00 62.27  ? 317 GLU E C   1 
ATOM   6683  O O   . GLU E 1 110 ? -64.341  34.284  56.785  1.00 60.06  ? 317 GLU E O   1 
ATOM   6684  C CB  . GLU E 1 110 ? -64.682  31.649  58.664  1.00 68.74  ? 317 GLU E CB  1 
ATOM   6685  C CG  . GLU E 1 110 ? -66.146  32.001  58.935  1.00 72.11  ? 317 GLU E CG  1 
ATOM   6686  C CD  . GLU E 1 110 ? -66.630  31.460  60.273  1.00 76.27  ? 317 GLU E CD  1 
ATOM   6687  O OE1 . GLU E 1 110 ? -67.219  32.236  61.060  1.00 79.00  ? 317 GLU E OE1 1 
ATOM   6688  O OE2 . GLU E 1 110 ? -66.407  30.257  60.541  1.00 78.84  ? 317 GLU E OE2 1 
ATOM   6689  N N   . GLY E 1 111 ? -65.965  32.959  55.958  1.00 59.81  ? 318 GLY E N   1 
ATOM   6690  C CA  . GLY E 1 111 ? -66.742  34.060  55.431  1.00 54.35  ? 318 GLY E CA  1 
ATOM   6691  C C   . GLY E 1 111 ? -66.260  34.652  54.127  1.00 55.17  ? 318 GLY E C   1 
ATOM   6692  O O   . GLY E 1 111 ? -66.886  35.602  53.637  1.00 57.80  ? 318 GLY E O   1 
ATOM   6693  N N   . THR E 1 112 ? -65.177  34.136  53.542  1.00 52.84  ? 319 THR E N   1 
ATOM   6694  C CA  . THR E 1 112 ? -64.670  34.708  52.299  1.00 55.03  ? 319 THR E CA  1 
ATOM   6695  C C   . THR E 1 112 ? -65.697  34.578  51.184  1.00 57.41  ? 319 THR E C   1 
ATOM   6696  O O   . THR E 1 112 ? -66.107  35.570  50.564  1.00 52.26  ? 319 THR E O   1 
ATOM   6697  C CB  . THR E 1 112 ? -63.370  34.017  51.888  1.00 57.11  ? 319 THR E CB  1 
ATOM   6698  O OG1 . THR E 1 112 ? -62.491  33.923  53.014  1.00 58.46  ? 319 THR E OG1 1 
ATOM   6699  C CG2 . THR E 1 112 ? -62.696  34.798  50.759  1.00 48.92  ? 319 THR E CG2 1 
ATOM   6700  N N   . ILE E 1 113 ? -66.118  33.342  50.920  1.00 56.53  ? 320 ILE E N   1 
ATOM   6701  C CA  . ILE E 1 113 ? -66.994  33.079  49.785  1.00 51.01  ? 320 ILE E CA  1 
ATOM   6702  C C   . ILE E 1 113 ? -68.253  33.938  49.828  1.00 52.64  ? 320 ILE E C   1 
ATOM   6703  O O   . ILE E 1 113 ? -68.589  34.550  48.802  1.00 54.37  ? 320 ILE E O   1 
ATOM   6704  C CB  . ILE E 1 113 ? -67.284  31.570  49.695  1.00 52.76  ? 320 ILE E CB  1 
ATOM   6705  C CG1 . ILE E 1 113 ? -66.003  30.823  49.339  1.00 52.77  ? 320 ILE E CG1 1 
ATOM   6706  C CG2 . ILE E 1 113 ? -68.383  31.273  48.714  1.00 51.68  ? 320 ILE E CG2 1 
ATOM   6707  C CD1 . ILE E 1 113 ? -66.161  29.365  49.223  1.00 51.09  ? 320 ILE E CD1 1 
ATOM   6708  N N   . PRO E 1 114 ? -68.969  34.059  50.951  1.00 48.06  ? 321 PRO E N   1 
ATOM   6709  C CA  . PRO E 1 114 ? -70.141  34.940  50.953  1.00 47.97  ? 321 PRO E CA  1 
ATOM   6710  C C   . PRO E 1 114 ? -69.814  36.429  50.834  1.00 54.37  ? 321 PRO E C   1 
ATOM   6711  O O   . PRO E 1 114 ? -70.628  37.167  50.262  1.00 52.09  ? 321 PRO E O   1 
ATOM   6712  C CB  . PRO E 1 114 ? -70.825  34.609  52.286  1.00 48.59  ? 321 PRO E CB  1 
ATOM   6713  C CG  . PRO E 1 114 ? -69.816  33.969  53.089  1.00 48.42  ? 321 PRO E CG  1 
ATOM   6714  C CD  . PRO E 1 114 ? -68.968  33.204  52.144  1.00 53.33  ? 321 PRO E CD  1 
ATOM   6715  N N   . LYS E 1 115 ? -68.669  36.881  51.336  1.00 53.13  ? 322 LYS E N   1 
ATOM   6716  C CA  . LYS E 1 115 ? -68.286  38.310  51.219  1.00 52.13  ? 322 LYS E CA  1 
ATOM   6717  C C   . LYS E 1 115 ? -67.983  38.655  49.765  1.00 52.73  ? 322 LYS E C   1 
ATOM   6718  O O   . LYS E 1 115 ? -68.061  39.832  49.425  1.00 51.72  ? 322 LYS E O   1 
ATOM   6719  C CB  . LYS E 1 115 ? -67.065  38.624  52.083  1.00 54.63  ? 322 LYS E CB  1 
ATOM   6720  N N   . LEU E 1 116 ? -67.671  37.655  48.952  1.00 49.06  ? 323 LEU E N   1 
ATOM   6721  C CA  . LEU E 1 116 ? -67.299  37.892  47.542  1.00 50.63  ? 323 LEU E CA  1 
ATOM   6722  C C   . LEU E 1 116 ? -68.475  37.596  46.619  1.00 53.36  ? 323 LEU E C   1 
ATOM   6723  O O   . LEU E 1 116 ? -68.670  38.367  45.689  1.00 54.93  ? 323 LEU E O   1 
ATOM   6724  C CB  . LEU E 1 116 ? -66.142  36.951  47.208  1.00 55.23  ? 323 LEU E CB  1 
ATOM   6725  C CG  . LEU E 1 116 ? -64.747  37.414  47.611  1.00 57.80  ? 323 LEU E CG  1 
ATOM   6726  C CD1 . LEU E 1 116 ? -63.721  36.358  47.246  1.00 56.07  ? 323 LEU E CD1 1 
ATOM   6727  C CD2 . LEU E 1 116 ? -64.408  38.733  46.941  1.00 54.01  ? 323 LEU E CD2 1 
ATOM   6728  N N   . PHE E 1 117 ? -69.242  36.541  46.879  1.00 51.17  ? 324 PHE E N   1 
ATOM   6729  C CA  . PHE E 1 117 ? -70.281  36.128  45.903  1.00 51.53  ? 324 PHE E CA  1 
ATOM   6730  C C   . PHE E 1 117 ? -71.712  36.223  46.426  1.00 49.11  ? 324 PHE E C   1 
ATOM   6731  O O   . PHE E 1 117 ? -72.605  35.971  45.622  1.00 52.54  ? 324 PHE E O   1 
ATOM   6732  C CB  . PHE E 1 117 ? -70.039  34.680  45.471  1.00 46.90  ? 324 PHE E CB  1 
ATOM   6733  C CG  . PHE E 1 117 ? -68.649  34.324  45.009  1.00 47.37  ? 324 PHE E CG  1 
ATOM   6734  C CD1 . PHE E 1 117 ? -68.237  34.598  43.718  1.00 50.84  ? 324 PHE E CD1 1 
ATOM   6735  C CD2 . PHE E 1 117 ? -67.766  33.669  45.850  1.00 46.74  ? 324 PHE E CD2 1 
ATOM   6736  C CE1 . PHE E 1 117 ? -66.965  34.253  43.293  1.00 49.94  ? 324 PHE E CE1 1 
ATOM   6737  C CE2 . PHE E 1 117 ? -66.493  33.329  45.427  1.00 52.59  ? 324 PHE E CE2 1 
ATOM   6738  C CZ  . PHE E 1 117 ? -66.096  33.619  44.146  1.00 51.40  ? 324 PHE E CZ  1 
ATOM   6739  N N   . ARG E 1 118 ? -71.939  36.619  47.677  1.00 46.09  ? 325 ARG E N   1 
ATOM   6740  C CA  . ARG E 1 118 ? -73.305  36.567  48.177  1.00 47.09  ? 325 ARG E CA  1 
ATOM   6741  C C   . ARG E 1 118 ? -73.925  37.958  48.240  1.00 49.38  ? 325 ARG E C   1 
ATOM   6742  O O   . ARG E 1 118 ? -73.327  38.881  48.795  1.00 51.85  ? 325 ARG E O   1 
ATOM   6743  C CB  . ARG E 1 118 ? -73.352  35.909  49.556  1.00 49.31  ? 325 ARG E CB  1 
ATOM   6744  C CG  . ARG E 1 118 ? -74.747  35.827  50.136  1.00 50.80  ? 325 ARG E CG  1 
ATOM   6745  C CD  . ARG E 1 118 ? -74.763  36.336  51.554  1.00 51.42  ? 325 ARG E CD  1 
ATOM   6746  N NE  . ARG E 1 118 ? -74.569  35.238  52.489  1.00 53.48  ? 325 ARG E NE  1 
ATOM   6747  C CZ  . ARG E 1 118 ? -74.177  35.379  53.750  1.00 62.70  ? 325 ARG E CZ  1 
ATOM   6748  N NH1 . ARG E 1 118 ? -73.919  36.591  54.247  1.00 64.89  ? 325 ARG E NH1 1 
ATOM   6749  N NH2 . ARG E 1 118 ? -74.031  34.295  54.508  1.00 63.53  ? 325 ARG E NH2 1 
ATOM   6750  N N   . GLY E 1 119 ? -75.128  38.093  47.680  1.00 47.38  ? 326 GLY E N   1 
ATOM   6751  C CA  . GLY E 1 119 ? -75.945  39.288  47.810  1.00 44.21  ? 326 GLY E CA  1 
ATOM   6752  C C   . GLY E 1 119 ? -77.327  38.984  48.370  1.00 51.67  ? 326 GLY E C   1 
ATOM   6753  O O   . GLY E 1 119 ? -77.549  37.890  48.906  1.00 49.17  ? 326 GLY E O   1 
ATOM   6754  N N   . LYS E 1 120 ? -78.277  39.913  48.217  1.00 53.39  ? 327 LYS E N   1 
ATOM   6755  C CA  . LYS E 1 120 ? -79.537  39.856  48.960  1.00 53.21  ? 327 LYS E CA  1 
ATOM   6756  C C   . LYS E 1 120 ? -80.675  40.504  48.174  1.00 48.67  ? 327 LYS E C   1 
ATOM   6757  O O   . LYS E 1 120 ? -80.580  41.681  47.824  1.00 47.50  ? 327 LYS E O   1 
ATOM   6758  C CB  . LYS E 1 120 ? -79.345  40.541  50.318  1.00 52.64  ? 327 LYS E CB  1 
ATOM   6759  C CG  . LYS E 1 120 ? -80.623  40.807  51.108  1.00 59.26  ? 327 LYS E CG  1 
ATOM   6760  C CD  . LYS E 1 120 ? -80.893  39.730  52.148  1.00 54.97  ? 327 LYS E CD  1 
ATOM   6761  C CE  . LYS E 1 120 ? -80.015  39.859  53.365  1.00 51.31  ? 327 LYS E CE  1 
ATOM   6762  N NZ  . LYS E 1 120 ? -80.511  38.847  54.361  1.00 66.83  ? 327 LYS E NZ  1 
ATOM   6763  N N   . MET E 1 121 ? -81.689  39.701  47.865  1.00 47.53  ? 328 MET E N   1 
ATOM   6764  C CA  . MET E 1 121 ? -82.869  40.188  47.122  1.00 50.14  ? 328 MET E CA  1 
ATOM   6765  C C   . MET E 1 121 ? -84.032  40.394  48.082  1.00 54.57  ? 328 MET E C   1 
ATOM   6766  O O   . MET E 1 121 ? -83.929  39.999  49.249  1.00 48.50  ? 328 MET E O   1 
ATOM   6767  C CB  . MET E 1 121 ? -83.347  39.142  46.116  1.00 47.18  ? 328 MET E CB  1 
ATOM   6768  C CG  . MET E 1 121 ? -82.387  38.815  45.017  1.00 57.65  ? 328 MET E CG  1 
ATOM   6769  S SD  . MET E 1 121 ? -82.703  37.160  44.362  1.00 72.93  ? 328 MET E SD  1 
ATOM   6770  C CE  . MET E 1 121 ? -84.083  36.634  45.375  1.00 46.95  ? 328 MET E CE  1 
ATOM   6771  N N   . VAL E 1 122 ? -85.113  40.967  47.567  1.00 48.52  ? 329 VAL E N   1 
ATOM   6772  C CA  . VAL E 1 122 ? -86.333  41.154  48.392  1.00 45.03  ? 329 VAL E CA  1 
ATOM   6773  C C   . VAL E 1 122 ? -87.566  40.991  47.502  1.00 50.41  ? 329 VAL E C   1 
ATOM   6774  O O   . VAL E 1 122 ? -87.744  41.778  46.573  1.00 48.15  ? 329 VAL E O   1 
ATOM   6775  C CB  . VAL E 1 122 ? -86.292  42.475  49.184  1.00 54.47  ? 329 VAL E CB  1 
ATOM   6776  C CG1 . VAL E 1 122 ? -86.025  43.694  48.321  1.00 52.58  ? 329 VAL E CG1 1 
ATOM   6777  C CG2 . VAL E 1 122 ? -87.493  42.647  50.095  1.00 60.57  ? 329 VAL E CG2 1 
ATOM   6778  N N   . SER E 1 123 ? -88.330  39.928  47.730  1.00 58.59  ? 330 SER E N   1 
ATOM   6779  C CA  . SER E 1 123 ? -89.593  39.706  47.028  1.00 53.16  ? 330 SER E CA  1 
ATOM   6780  C C   . SER E 1 123 ? -90.698  40.455  47.755  1.00 52.12  ? 330 SER E C   1 
ATOM   6781  O O   . SER E 1 123 ? -90.859  40.298  48.969  1.00 57.10  ? 330 SER E O   1 
ATOM   6782  C CB  . SER E 1 123 ? -89.947  38.221  46.959  1.00 50.34  ? 330 SER E CB  1 
ATOM   6783  O OG  . SER E 1 123 ? -89.005  37.469  46.209  1.00 60.98  ? 330 SER E OG  1 
ATOM   6784  N N   . TYR E 1 124 ? -91.466  41.259  47.010  1.00 49.81  ? 331 TYR E N   1 
ATOM   6785  C CA  . TYR E 1 124 ? -92.573  42.057  47.600  1.00 49.21  ? 331 TYR E CA  1 
ATOM   6786  C C   . TYR E 1 124 ? -93.917  41.540  47.083  1.00 53.58  ? 331 TYR E C   1 
ATOM   6787  O O   . TYR E 1 124 ? -94.089  41.502  45.862  1.00 53.86  ? 331 TYR E O   1 
ATOM   6788  C CB  . TYR E 1 124 ? -92.447  43.527  47.203  1.00 48.99  ? 331 TYR E CB  1 
ATOM   6789  C CG  . TYR E 1 124 ? -91.229  44.241  47.729  1.00 52.65  ? 331 TYR E CG  1 
ATOM   6790  C CD1 . TYR E 1 124 ? -91.117  44.564  49.070  1.00 55.12  ? 331 TYR E CD1 1 
ATOM   6791  C CD2 . TYR E 1 124 ? -90.200  44.616  46.882  1.00 55.50  ? 331 TYR E CD2 1 
ATOM   6792  C CE1 . TYR E 1 124 ? -90.008  45.229  49.564  1.00 55.92  ? 331 TYR E CE1 1 
ATOM   6793  C CE2 . TYR E 1 124 ? -89.085  45.284  47.358  1.00 61.32  ? 331 TYR E CE2 1 
ATOM   6794  C CZ  . TYR E 1 124 ? -88.989  45.594  48.703  1.00 60.46  ? 331 TYR E CZ  1 
ATOM   6795  O OH  . TYR E 1 124 ? -87.894  46.250  49.186  1.00 65.39  ? 331 TYR E OH  1 
ATOM   6796  N N   . ILE E 1 125 ? -94.849  41.209  47.978  1.00 52.07  ? 332 ILE E N   1 
ATOM   6797  C CA  . ILE E 1 125 ? -96.171  40.641  47.589  1.00 50.36  ? 332 ILE E CA  1 
ATOM   6798  C C   . ILE E 1 125 ? -97.279  41.588  48.061  1.00 54.90  ? 332 ILE E C   1 
ATOM   6799  O O   . ILE E 1 125 ? -97.345  41.843  49.260  1.00 57.26  ? 332 ILE E O   1 
ATOM   6800  C CB  . ILE E 1 125 ? -96.368  39.211  48.139  1.00 57.34  ? 332 ILE E CB  1 
ATOM   6801  C CG1 . ILE E 1 125 ? -95.355  38.218  47.565  1.00 50.09  ? 332 ILE E CG1 1 
ATOM   6802  C CG2 . ILE E 1 125 ? -97.790  38.737  47.902  1.00 49.93  ? 332 ILE E CG2 1 
ATOM   6803  C CD1 . ILE E 1 125 ? -94.404  37.657  48.591  1.00 54.66  ? 332 ILE E CD1 1 
ATOM   6804  N N   . GLN E 1 126 ? -98.107  42.086  47.141  1.00 55.58  ? 333 GLN E N   1 
ATOM   6805  C CA  . GLN E 1 126 ? -99.248  42.964  47.500  1.00 52.30  ? 333 GLN E CA  1 
ATOM   6806  C C   . GLN E 1 126 ? -100.548 42.371  46.965  1.00 55.81  ? 333 GLN E C   1 
ATOM   6807  O O   . GLN E 1 126 ? -100.672 42.235  45.751  1.00 55.55  ? 333 GLN E O   1 
ATOM   6808  C CB  . GLN E 1 126 ? -99.076  44.357  46.904  1.00 59.63  ? 333 GLN E CB  1 
ATOM   6809  C CG  . GLN E 1 126 ? -99.480  45.480  47.844  1.00 50.51  ? 333 GLN E CG  1 
ATOM   6810  C CD  . GLN E 1 126 ? -100.974 45.672  47.911  1.00 60.41  ? 333 GLN E CD  1 
ATOM   6811  O OE1 . GLN E 1 126 ? -101.616 46.009  46.922  1.00 82.18  ? 333 GLN E OE1 1 
ATOM   6812  N NE2 . GLN E 1 126 ? -101.540 45.454  49.086  1.00 64.78  ? 333 GLN E NE2 1 
ATOM   6813  N N   . CYS E 1 127 ? -101.496 42.082  47.853  1.00 30.00  ? 334 CYS E N   1 
ATOM   6814  C CA  . CYS E 1 127 ? -102.811 41.546  47.430  1.00 30.00  ? 334 CYS E CA  1 
ATOM   6815  C C   . CYS E 1 127 ? -103.594 42.641  46.707  1.00 30.00  ? 334 CYS E C   1 
ATOM   6816  O O   . CYS E 1 127 ? -103.578 43.782  47.176  1.00 30.00  ? 334 CYS E O   1 
ATOM   6817  C CB  . CYS E 1 127 ? -103.584 41.004  48.622  1.00 30.00  ? 334 CYS E CB  1 
ATOM   6818  S SG  . CYS E 1 127 ? -103.014 39.376  49.150  1.00 30.00  ? 334 CYS E SG  1 
ATOM   6819  N N   . LYS E 1 128 ? -104.297 42.282  45.638  1.00 58.03  ? 335 LYS E N   1 
ATOM   6820  C CA  . LYS E 1 128 ? -105.014 43.271  44.793  1.00 59.59  ? 335 LYS E CA  1 
ATOM   6821  C C   . LYS E 1 128 ? -106.346 43.727  45.406  1.00 59.66  ? 335 LYS E C   1 
ATOM   6822  O O   . LYS E 1 128 ? -106.518 44.942  45.547  1.00 56.44  ? 335 LYS E O   1 
ATOM   6823  C CB  . LYS E 1 128 ? -105.219 42.640  43.415  1.00 57.08  ? 335 LYS E CB  1 
ATOM   6824  C CG  . LYS E 1 128 ? -103.936 42.246  42.700  1.00 56.55  ? 335 LYS E CG  1 
ATOM   6825  C CD  . LYS E 1 128 ? -104.155 41.874  41.259  1.00 57.59  ? 335 LYS E CD  1 
ATOM   6826  C CE  . LYS E 1 128 ? -103.951 43.046  40.326  1.00 70.94  ? 335 LYS E CE  1 
ATOM   6827  N NZ  . LYS E 1 128 ? -104.072 42.638  38.908  1.00 72.57  ? 335 LYS E NZ  1 
ATOM   6828  N N   . GLU E 1 129 ? -107.254 42.809  45.742  1.00 62.83  ? 336 GLU E N   1 
ATOM   6829  C CA  . GLU E 1 129 ? -108.574 43.211  46.221  1.00 63.40  ? 336 GLU E CA  1 
ATOM   6830  C C   . GLU E 1 129 ? -108.759 43.091  47.736  1.00 65.50  ? 336 GLU E C   1 
ATOM   6831  O O   . GLU E 1 129 ? -109.881 43.258  48.230  1.00 70.97  ? 336 GLU E O   1 
ATOM   6832  C CB  . GLU E 1 129 ? -109.665 42.415  45.493  1.00 62.58  ? 336 GLU E CB  1 
ATOM   6833  C CG  . GLU E 1 129 ? -109.371 40.948  45.343  1.00 74.97  ? 336 GLU E CG  1 
ATOM   6834  C CD  . GLU E 1 129 ? -110.391 40.231  44.473  1.00 89.66  ? 336 GLU E CD  1 
ATOM   6835  O OE1 . GLU E 1 129 ? -111.475 40.814  44.246  1.00 89.83  ? 336 GLU E OE1 1 
ATOM   6836  O OE2 . GLU E 1 129 ? -110.104 39.093  44.015  1.00 96.05  ? 336 GLU E OE2 1 
ATOM   6837  N N   . VAL E 1 130 ? -107.699 42.729  48.460  1.00 63.78  ? 337 VAL E N   1 
ATOM   6838  C CA  . VAL E 1 130 ? -107.761 42.746  49.953  1.00 61.09  ? 337 VAL E CA  1 
ATOM   6839  C C   . VAL E 1 130 ? -106.547 43.530  50.448  1.00 61.21  ? 337 VAL E C   1 
ATOM   6840  O O   . VAL E 1 130 ? -105.551 43.625  49.717  1.00 59.77  ? 337 VAL E O   1 
ATOM   6841  C CB  . VAL E 1 130 ? -107.866 41.367  50.635  1.00 66.08  ? 337 VAL E CB  1 
ATOM   6842  C CG1 . VAL E 1 130 ? -109.172 40.650  50.337  1.00 60.95  ? 337 VAL E CG1 1 
ATOM   6843  C CG2 . VAL E 1 130 ? -106.667 40.475  50.388  1.00 64.98  ? 337 VAL E CG2 1 
ATOM   6844  N N   . ASP E 1 131 ? -106.640 44.078  51.651  1.00 69.43  ? 338 ASP E N   1 
ATOM   6845  C CA  . ASP E 1 131 ? -105.572 44.939  52.159  1.00 71.20  ? 338 ASP E CA  1 
ATOM   6846  C C   . ASP E 1 131 ? -104.561 44.095  52.936  1.00 67.69  ? 338 ASP E C   1 
ATOM   6847  O O   . ASP E 1 131 ? -104.592 43.991  54.161  1.00 67.02  ? 338 ASP E O   1 
ATOM   6848  C CB  . ASP E 1 131 ? -106.150 46.066  53.001  1.00 63.69  ? 338 ASP E CB  1 
ATOM   6849  C CG  . ASP E 1 131 ? -105.090 47.043  53.429  1.00 84.08  ? 338 ASP E CG  1 
ATOM   6850  O OD1 . ASP E 1 131 ? -103.941 46.914  52.933  1.00 84.33  ? 338 ASP E OD1 1 
ATOM   6851  O OD2 . ASP E 1 131 ? -105.394 47.936  54.250  1.00 93.83  ? 338 ASP E OD2 1 
ATOM   6852  N N   . TYR E 1 132 ? -103.692 43.409  52.183  1.00 61.26  ? 339 TYR E N   1 
ATOM   6853  C CA  . TYR E 1 132 ? -102.668 42.520  52.788  1.00 57.42  ? 339 TYR E CA  1 
ATOM   6854  C C   . TYR E 1 132 ? -101.360 42.650  52.000  1.00 61.77  ? 339 TYR E C   1 
ATOM   6855  O O   . TYR E 1 132 ? -101.411 42.708  50.765  1.00 61.41  ? 339 TYR E O   1 
ATOM   6856  C CB  . TYR E 1 132 ? -103.193 41.085  52.799  1.00 55.95  ? 339 TYR E CB  1 
ATOM   6857  C CG  . TYR E 1 132 ? -102.364 40.052  53.517  1.00 57.67  ? 339 TYR E CG  1 
ATOM   6858  C CD1 . TYR E 1 132 ? -101.264 39.465  52.915  1.00 54.52  ? 339 TYR E CD1 1 
ATOM   6859  C CD2 . TYR E 1 132 ? -102.713 39.618  54.783  1.00 56.32  ? 339 TYR E CD2 1 
ATOM   6860  C CE1 . TYR E 1 132 ? -100.509 38.506  53.565  1.00 55.36  ? 339 TYR E CE1 1 
ATOM   6861  C CE2 . TYR E 1 132 ? -101.973 38.654  55.446  1.00 51.78  ? 339 TYR E CE2 1 
ATOM   6862  C CZ  . TYR E 1 132 ? -100.868 38.095  54.833  1.00 55.24  ? 339 TYR E CZ  1 
ATOM   6863  O OH  . TYR E 1 132 ? -100.133 37.143  55.474  1.00 64.78  ? 339 TYR E OH  1 
ATOM   6864  N N   . ARG E 1 133 ? -100.226 42.633  52.697  1.00 59.43  ? 340 ARG E N   1 
ATOM   6865  C CA  . ARG E 1 133 ? -98.896  42.782  52.057  1.00 62.56  ? 340 ARG E CA  1 
ATOM   6866  C C   . ARG E 1 133 ? -97.897  41.894  52.805  1.00 59.15  ? 340 ARG E C   1 
ATOM   6867  O O   . ARG E 1 133 ? -98.074  41.717  54.021  1.00 57.51  ? 340 ARG E O   1 
ATOM   6868  C CB  . ARG E 1 133 ? -98.487  44.252  52.144  1.00 59.01  ? 340 ARG E CB  1 
ATOM   6869  C CG  . ARG E 1 133 ? -97.577  44.752  51.036  1.00 57.27  ? 340 ARG E CG  1 
ATOM   6870  C CD  . ARG E 1 133 ? -97.371  46.241  51.223  1.00 66.68  ? 340 ARG E CD  1 
ATOM   6871  N NE  . ARG E 1 133 ? -98.552  47.015  50.867  1.00 69.76  ? 340 ARG E NE  1 
ATOM   6872  C CZ  . ARG E 1 133 ? -99.279  47.736  51.712  1.00 75.83  ? 340 ARG E CZ  1 
ATOM   6873  N NH1 . ARG E 1 133 ? -98.957  47.791  52.993  1.00 70.79  ? 340 ARG E NH1 1 
ATOM   6874  N NH2 . ARG E 1 133 ? -100.332 48.398  51.272  1.00 73.76  ? 340 ARG E NH2 1 
ATOM   6875  N N   . SER E 1 134 ? -96.883  41.372  52.112  1.00 53.17  ? 341 SER E N   1 
ATOM   6876  C CA  . SER E 1 134 ? -95.846  40.541  52.779  1.00 60.77  ? 341 SER E CA  1 
ATOM   6877  C C   . SER E 1 134 ? -94.461  40.753  52.165  1.00 64.90  ? 341 SER E C   1 
ATOM   6878  O O   . SER E 1 134 ? -94.391  41.167  51.002  1.00 69.44  ? 341 SER E O   1 
ATOM   6879  C CB  . SER E 1 134 ? -96.210  39.092  52.752  1.00 61.56  ? 341 SER E CB  1 
ATOM   6880  O OG  . SER E 1 134 ? -95.737  38.437  53.917  1.00 63.15  ? 341 SER E OG  1 
ATOM   6881  N N   . ASP E 1 135 ? -93.407  40.439  52.923  1.00 61.60  ? 342 ASP E N   1 
ATOM   6882  C CA  . ASP E 1 135 ? -92.009  40.609  52.449  1.00 61.24  ? 342 ASP E CA  1 
ATOM   6883  C C   . ASP E 1 135 ? -91.192  39.342  52.712  1.00 59.06  ? 342 ASP E C   1 
ATOM   6884  O O   . ASP E 1 135 ? -91.581  38.571  53.595  1.00 70.76  ? 342 ASP E O   1 
ATOM   6885  C CB  . ASP E 1 135 ? -91.333  41.805  53.120  1.00 67.15  ? 342 ASP E CB  1 
ATOM   6886  C CG  . ASP E 1 135 ? -91.743  43.167  52.601  1.00 67.09  ? 342 ASP E CG  1 
ATOM   6887  O OD1 . ASP E 1 135 ? -92.446  43.222  51.585  1.00 56.01  ? 342 ASP E OD1 1 
ATOM   6888  O OD2 . ASP E 1 135 ? -91.351  44.163  53.227  1.00 77.11  ? 342 ASP E OD2 1 
ATOM   6889  N N   . ARG E 1 136 ? -90.095  39.152  51.986  1.00 50.05  ? 343 ARG E N   1 
ATOM   6890  C CA  . ARG E 1 136 ? -89.188  37.985  52.120  1.00 57.33  ? 343 ARG E CA  1 
ATOM   6891  C C   . ARG E 1 136 ? -87.795  38.408  51.656  1.00 58.91  ? 343 ARG E C   1 
ATOM   6892  O O   . ARG E 1 136 ? -87.601  38.555  50.438  1.00 49.77  ? 343 ARG E O   1 
ATOM   6893  C CB  . ARG E 1 136 ? -89.673  36.765  51.337  1.00 55.18  ? 343 ARG E CB  1 
ATOM   6894  C CG  . ARG E 1 136 ? -89.007  35.452  51.725  1.00 57.74  ? 343 ARG E CG  1 
ATOM   6895  C CD  . ARG E 1 136 ? -89.064  35.105  53.197  1.00 65.49  ? 343 ARG E CD  1 
ATOM   6896  N NE  . ARG E 1 136 ? -90.299  34.450  53.603  1.00 72.10  ? 343 ARG E NE  1 
ATOM   6897  C CZ  . ARG E 1 136 ? -91.004  34.783  54.678  1.00 69.83  ? 343 ARG E CZ  1 
ATOM   6898  N NH1 . ARG E 1 136 ? -90.597  35.766  55.460  1.00 71.08  ? 343 ARG E NH1 1 
ATOM   6899  N NH2 . ARG E 1 136 ? -92.115  34.133  54.971  1.00 64.90  ? 343 ARG E NH2 1 
ATOM   6900  N N   . ARG E 1 137 ? -86.884  38.637  52.597  1.00 58.64  ? 344 ARG E N   1 
ATOM   6901  C CA  . ARG E 1 137 ? -85.481  38.961  52.251  1.00 56.43  ? 344 ARG E CA  1 
ATOM   6902  C C   . ARG E 1 137 ? -84.735  37.642  52.080  1.00 55.06  ? 344 ARG E C   1 
ATOM   6903  O O   . ARG E 1 137 ? -84.777  36.826  53.006  1.00 60.23  ? 344 ARG E O   1 
ATOM   6904  C CB  . ARG E 1 137 ? -84.855  39.834  53.337  1.00 56.25  ? 344 ARG E CB  1 
ATOM   6905  C CG  . ARG E 1 137 ? -84.961  41.326  53.073  1.00 60.34  ? 344 ARG E CG  1 
ATOM   6906  C CD  . ARG E 1 137 ? -85.359  42.087  54.320  1.00 57.68  ? 344 ARG E CD  1 
ATOM   6907  N NE  . ARG E 1 137 ? -86.271  43.171  53.995  1.00 61.76  ? 344 ARG E NE  1 
ATOM   6908  C CZ  . ARG E 1 137 ? -87.591  43.108  54.108  1.00 61.83  ? 344 ARG E CZ  1 
ATOM   6909  N NH1 . ARG E 1 137 ? -88.329  44.151  53.776  1.00 59.66  ? 344 ARG E NH1 1 
ATOM   6910  N NH2 . ARG E 1 137 ? -88.168  42.009  54.555  1.00 58.84  ? 344 ARG E NH2 1 
ATOM   6911  N N   . GLU E 1 138 ? -84.062  37.458  50.949  1.00 54.56  ? 345 GLU E N   1 
ATOM   6912  C CA  . GLU E 1 138 ? -83.414  36.158  50.652  1.00 52.79  ? 345 GLU E CA  1 
ATOM   6913  C C   . GLU E 1 138 ? -81.998  36.346  50.110  1.00 52.79  ? 345 GLU E C   1 
ATOM   6914  O O   . GLU E 1 138 ? -81.791  37.249  49.303  1.00 50.39  ? 345 GLU E O   1 
ATOM   6915  C CB  . GLU E 1 138 ? -84.269  35.376  49.659  1.00 45.84  ? 345 GLU E CB  1 
ATOM   6916  C CG  . GLU E 1 138 ? -85.495  34.735  50.274  1.00 52.49  ? 345 GLU E CG  1 
ATOM   6917  C CD  . GLU E 1 138 ? -86.496  34.210  49.262  1.00 65.46  ? 345 GLU E CD  1 
ATOM   6918  O OE1 . GLU E 1 138 ? -87.170  35.030  48.614  1.00 63.82  ? 345 GLU E OE1 1 
ATOM   6919  O OE2 . GLU E 1 138 ? -86.594  32.984  49.127  1.00 64.36  ? 345 GLU E OE2 1 
ATOM   6920  N N   . ASP E 1 139 ? -81.068  35.496  50.544  1.00 53.10  ? 346 ASP E N   1 
ATOM   6921  C CA  . ASP E 1 139 ? -79.702  35.526  50.057  1.00 49.32  ? 346 ASP E CA  1 
ATOM   6922  C C   . ASP E 1 139 ? -79.619  34.824  48.709  1.00 48.39  ? 346 ASP E C   1 
ATOM   6923  O O   . ASP E 1 139 ? -80.448  33.978  48.373  1.00 49.89  ? 346 ASP E O   1 
ATOM   6924  C CB  . ASP E 1 139 ? -78.756  34.861  51.064  1.00 42.46  ? 346 ASP E CB  1 
ATOM   6925  C CG  . ASP E 1 139 ? -78.488  35.739  52.279  1.00 47.84  ? 346 ASP E CG  1 
ATOM   6926  O OD1 . ASP E 1 139 ? -78.927  36.900  52.290  1.00 47.65  ? 346 ASP E OD1 1 
ATOM   6927  O OD2 . ASP E 1 139 ? -77.847  35.271  53.237  1.00 55.30  ? 346 ASP E OD2 1 
ATOM   6928  N N   . TYR E 1 140 ? -78.623  35.211  47.920  1.00 46.14  ? 347 TYR E N   1 
ATOM   6929  C CA  . TYR E 1 140 ? -78.308  34.532  46.675  1.00 43.39  ? 347 TYR E CA  1 
ATOM   6930  C C   . TYR E 1 140 ? -76.802  34.568  46.492  1.00 52.04  ? 347 TYR E C   1 
ATOM   6931  O O   . TYR E 1 140 ? -76.121  35.471  46.992  1.00 51.92  ? 347 TYR E O   1 
ATOM   6932  C CB  . TYR E 1 140 ? -78.994  35.168  45.447  1.00 41.37  ? 347 TYR E CB  1 
ATOM   6933  C CG  . TYR E 1 140 ? -78.510  36.567  45.146  1.00 47.65  ? 347 TYR E CG  1 
ATOM   6934  C CD1 . TYR E 1 140 ? -79.111  37.667  45.742  1.00 48.23  ? 347 TYR E CD1 1 
ATOM   6935  C CD2 . TYR E 1 140 ? -77.440  36.794  44.278  1.00 46.12  ? 347 TYR E CD2 1 
ATOM   6936  C CE1 . TYR E 1 140 ? -78.679  38.931  45.481  1.00 45.14  ? 347 TYR E CE1 1 
ATOM   6937  C CE2 . TYR E 1 140 ? -77.001  38.066  44.018  1.00 41.46  ? 347 TYR E CE2 1 
ATOM   6938  C CZ  . TYR E 1 140 ? -77.625  39.130  44.633  1.00 45.81  ? 347 TYR E CZ  1 
ATOM   6939  O OH  . TYR E 1 140 ? -77.212  40.416  44.400  1.00 48.20  ? 347 TYR E OH  1 
ATOM   6940  N N   . TYR E 1 141 ? -76.291  33.566  45.781  1.00 47.50  ? 348 TYR E N   1 
ATOM   6941  C CA  . TYR E 1 141 ? -74.905  33.528  45.368  1.00 42.59  ? 348 TYR E CA  1 
ATOM   6942  C C   . TYR E 1 141 ? -74.768  33.590  43.858  1.00 49.33  ? 348 TYR E C   1 
ATOM   6943  O O   . TYR E 1 141 ? -73.663  33.398  43.338  1.00 54.16  ? 348 TYR E O   1 
ATOM   6944  C CB  . TYR E 1 141 ? -74.228  32.255  45.876  1.00 46.06  ? 348 TYR E CB  1 
ATOM   6945  C CG  . TYR E 1 141 ? -73.938  32.255  47.342  1.00 48.57  ? 348 TYR E CG  1 
ATOM   6946  C CD1 . TYR E 1 141 ? -74.957  32.392  48.269  1.00 49.66  ? 348 TYR E CD1 1 
ATOM   6947  C CD2 . TYR E 1 141 ? -72.637  32.110  47.807  1.00 49.31  ? 348 TYR E CD2 1 
ATOM   6948  C CE1 . TYR E 1 141 ? -74.689  32.400  49.615  1.00 50.65  ? 348 TYR E CE1 1 
ATOM   6949  C CE2 . TYR E 1 141 ? -72.361  32.107  49.144  1.00 49.46  ? 348 TYR E CE2 1 
ATOM   6950  C CZ  . TYR E 1 141 ? -73.389  32.257  50.046  1.00 51.00  ? 348 TYR E CZ  1 
ATOM   6951  O OH  . TYR E 1 141 ? -73.121  32.258  51.393  1.00 52.84  ? 348 TYR E OH  1 
ATOM   6952  N N   . ASP E 1 142 ? -75.892  33.787  43.193  1.00 45.65  ? 349 ASP E N   1 
ATOM   6953  C CA  . ASP E 1 142 ? -75.918  33.808  41.720  1.00 40.06  ? 349 ASP E CA  1 
ATOM   6954  C C   . ASP E 1 142 ? -77.285  34.301  41.286  1.00 41.94  ? 349 ASP E C   1 
ATOM   6955  O O   . ASP E 1 142 ? -78.218  34.293  42.097  1.00 41.19  ? 349 ASP E O   1 
ATOM   6956  C CB  . ASP E 1 142 ? -75.639  32.431  41.117  1.00 45.74  ? 349 ASP E CB  1 
ATOM   6957  C CG  . ASP E 1 142 ? -76.543  31.322  41.603  1.00 44.92  ? 349 ASP E CG  1 
ATOM   6958  O OD1 . ASP E 1 142 ? -77.083  31.406  42.719  1.00 48.98  ? 349 ASP E OD1 1 
ATOM   6959  O OD2 . ASP E 1 142 ? -76.690  30.385  40.854  1.00 39.76  ? 349 ASP E OD2 1 
ATOM   6960  N N   . ILE E 1 143 ? -77.381  34.710  40.035  1.00 47.24  ? 350 ILE E N   1 
ATOM   6961  C CA  . ILE E 1 143 ? -78.632  35.205  39.480  1.00 44.65  ? 350 ILE E CA  1 
ATOM   6962  C C   . ILE E 1 143 ? -78.927  34.416  38.212  1.00 46.25  ? 350 ILE E C   1 
ATOM   6963  O O   . ILE E 1 143 ? -78.034  34.174  37.389  1.00 50.51  ? 350 ILE E O   1 
ATOM   6964  C CB  . ILE E 1 143 ? -78.551  36.718  39.181  1.00 45.29  ? 350 ILE E CB  1 
ATOM   6965  C CG1 . ILE E 1 143 ? -77.891  37.459  40.337  1.00 41.24  ? 350 ILE E CG1 1 
ATOM   6966  C CG2 . ILE E 1 143 ? -79.912  37.308  38.917  1.00 43.30  ? 350 ILE E CG2 1 
ATOM   6967  C CD1 . ILE E 1 143 ? -77.832  38.911  40.112  1.00 46.02  ? 350 ILE E CD1 1 
ATOM   6968  N N   . GLN E 1 144 ? -80.173  34.006  38.065  1.00 40.82  ? 351 GLN E N   1 
ATOM   6969  C CA  . GLN E 1 144 ? -80.621  33.281  36.895  1.00 40.25  ? 351 GLN E CA  1 
ATOM   6970  C C   . GLN E 1 144 ? -81.413  34.244  36.010  1.00 49.88  ? 351 GLN E C   1 
ATOM   6971  O O   . GLN E 1 144 ? -82.439  34.796  36.441  1.00 49.80  ? 351 GLN E O   1 
ATOM   6972  C CB  . GLN E 1 144 ? -81.458  32.077  37.329  1.00 48.40  ? 351 GLN E CB  1 
ATOM   6973  C CG  . GLN E 1 144 ? -80.678  30.881  37.967  1.00 44.91  ? 351 GLN E CG  1 
ATOM   6974  C CD  . GLN E 1 144 ? -80.381  31.032  39.451  1.00 45.48  ? 351 GLN E CD  1 
ATOM   6975  O OE1 . GLN E 1 144 ? -81.246  31.381  40.251  1.00 50.92  ? 351 GLN E OE1 1 
ATOM   6976  N NE2 . GLN E 1 144 ? -79.139  30.767  39.824  1.00 50.18  ? 351 GLN E NE2 1 
ATOM   6977  N N   . LEU E 1 145 ? -80.931  34.465  34.779  1.00 56.66  ? 352 LEU E N   1 
ATOM   6978  C CA  . LEU E 1 145 ? -81.487  35.483  33.886  1.00 53.33  ? 352 LEU E CA  1 
ATOM   6979  C C   . LEU E 1 145 ? -82.239  34.848  32.720  1.00 52.24  ? 352 LEU E C   1 
ATOM   6980  O O   . LEU E 1 145 ? -81.720  33.946  32.055  1.00 51.68  ? 352 LEU E O   1 
ATOM   6981  C CB  . LEU E 1 145 ? -80.373  36.391  33.351  1.00 49.30  ? 352 LEU E CB  1 
ATOM   6982  C CG  . LEU E 1 145 ? -79.761  37.414  34.343  1.00 59.60  ? 352 LEU E CG  1 
ATOM   6983  C CD1 . LEU E 1 145 ? -78.947  38.525  33.675  1.00 56.24  ? 352 LEU E CD1 1 
ATOM   6984  C CD2 . LEU E 1 145 ? -80.813  38.041  35.249  1.00 59.19  ? 352 LEU E CD2 1 
ATOM   6985  N N   . SER E 1 146 ? -83.449  35.345  32.448  1.00 54.75  ? 353 SER E N   1 
ATOM   6986  C CA  . SER E 1 146 ? -84.253  34.825  31.338  1.00 56.10  ? 353 SER E CA  1 
ATOM   6987  C C   . SER E 1 146 ? -83.754  35.338  29.992  1.00 60.28  ? 353 SER E C   1 
ATOM   6988  O O   . SER E 1 146 ? -83.360  36.498  29.863  1.00 61.96  ? 353 SER E O   1 
ATOM   6989  C CB  . SER E 1 146 ? -85.715  35.220  31.498  1.00 56.28  ? 353 SER E CB  1 
ATOM   6990  O OG  . SER E 1 146 ? -86.083  35.218  32.856  1.00 67.63  ? 353 SER E OG  1 
ATOM   6991  N N   . ILE E 1 147 ? -83.797  34.476  28.976  1.00 66.34  ? 354 ILE E N   1 
ATOM   6992  C CA  . ILE E 1 147 ? -83.284  34.822  27.657  1.00 65.65  ? 354 ILE E CA  1 
ATOM   6993  C C   . ILE E 1 147 ? -84.389  34.949  26.604  1.00 66.80  ? 354 ILE E C   1 
ATOM   6994  O O   . ILE E 1 147 ? -84.260  35.775  25.695  1.00 68.97  ? 354 ILE E O   1 
ATOM   6995  C CB  . ILE E 1 147 ? -82.211  33.805  27.202  1.00 63.68  ? 354 ILE E CB  1 
ATOM   6996  C CG1 . ILE E 1 147 ? -81.131  33.662  28.264  1.00 61.67  ? 354 ILE E CG1 1 
ATOM   6997  C CG2 . ILE E 1 147 ? -81.567  34.212  25.886  1.00 64.41  ? 354 ILE E CG2 1 
ATOM   6998  C CD1 . ILE E 1 147 ? -80.563  34.972  28.730  1.00 59.93  ? 354 ILE E CD1 1 
ATOM   6999  N N   . LYS E 1 148 ? -85.478  34.181  26.704  1.00 68.40  ? 355 LYS E N   1 
ATOM   7000  C CA  . LYS E 1 148 ? -86.479  34.123  25.638  1.00 71.43  ? 355 LYS E CA  1 
ATOM   7001  C C   . LYS E 1 148 ? -87.138  35.473  25.388  1.00 64.18  ? 355 LYS E C   1 
ATOM   7002  O O   . LYS E 1 148 ? -87.868  35.984  26.244  1.00 65.06  ? 355 LYS E O   1 
ATOM   7003  C CB  . LYS E 1 148 ? -87.559  33.073  25.952  1.00 67.11  ? 355 LYS E CB  1 
ATOM   7004  N N   . GLY E 1 149 ? -86.901  36.038  24.204  1.00 60.43  ? 356 GLY E N   1 
ATOM   7005  C CA  . GLY E 1 149 ? -87.477  37.318  23.844  1.00 64.78  ? 356 GLY E CA  1 
ATOM   7006  C C   . GLY E 1 149 ? -86.809  38.506  24.499  1.00 70.94  ? 356 GLY E C   1 
ATOM   7007  O O   . GLY E 1 149 ? -87.474  39.516  24.767  1.00 75.78  ? 356 GLY E O   1 
ATOM   7008  N N   . LYS E 1 150 ? -85.509  38.407  24.773  1.00 65.04  ? 357 LYS E N   1 
ATOM   7009  C CA  . LYS E 1 150 ? -84.742  39.451  25.444  1.00 68.47  ? 357 LYS E CA  1 
ATOM   7010  C C   . LYS E 1 150 ? -83.411  39.568  24.714  1.00 68.44  ? 357 LYS E C   1 
ATOM   7011  O O   . LYS E 1 150 ? -82.687  38.576  24.596  1.00 64.68  ? 357 LYS E O   1 
ATOM   7012  C CB  . LYS E 1 150 ? -84.540  39.120  26.933  1.00 61.13  ? 357 LYS E CB  1 
ATOM   7013  N N   . LYS E 1 151 ? -83.087  40.766  24.215  1.00 68.14  ? 358 LYS E N   1 
ATOM   7014  C CA  . LYS E 1 151 ? -81.944  40.922  23.318  1.00 67.74  ? 358 LYS E CA  1 
ATOM   7015  C C   . LYS E 1 151 ? -80.621  41.200  24.030  1.00 68.08  ? 358 LYS E C   1 
ATOM   7016  O O   . LYS E 1 151 ? -79.557  40.885  23.483  1.00 66.86  ? 358 LYS E O   1 
ATOM   7017  C CB  . LYS E 1 151 ? -82.212  42.042  22.307  1.00 71.19  ? 358 LYS E CB  1 
ATOM   7018  N N   . ASN E 1 152 ? -80.643  41.773  25.225  1.00 67.63  ? 359 ASN E N   1 
ATOM   7019  C CA  . ASN E 1 152 ? -79.410  42.128  25.909  1.00 65.97  ? 359 ASN E CA  1 
ATOM   7020  C C   . ASN E 1 152 ? -79.585  41.851  27.396  1.00 67.52  ? 359 ASN E C   1 
ATOM   7021  O O   . ASN E 1 152 ? -80.667  41.470  27.853  1.00 68.80  ? 359 ASN E O   1 
ATOM   7022  C CB  . ASN E 1 152 ? -79.051  43.591  25.640  1.00 65.81  ? 359 ASN E CB  1 
ATOM   7023  C CG  . ASN E 1 152 ? -80.208  44.531  25.939  1.00 68.11  ? 359 ASN E CG  1 
ATOM   7024  O OD1 . ASN E 1 152 ? -80.967  44.319  26.883  1.00 68.45  ? 359 ASN E OD1 1 
ATOM   7025  N ND2 . ASN E 1 152 ? -80.350  45.573  25.133  1.00 79.27  ? 359 ASN E ND2 1 
ATOM   7026  N N   . ILE E 1 153 ? -78.519  42.064  28.168  1.00 67.42  ? 360 ILE E N   1 
ATOM   7027  C CA  . ILE E 1 153 ? -78.583  41.753  29.592  1.00 61.83  ? 360 ILE E CA  1 
ATOM   7028  C C   . ILE E 1 153 ? -79.385  42.773  30.382  1.00 63.91  ? 360 ILE E C   1 
ATOM   7029  O O   . ILE E 1 153 ? -79.863  42.441  31.477  1.00 63.91  ? 360 ILE E O   1 
ATOM   7030  C CB  . ILE E 1 153 ? -77.183  41.636  30.201  1.00 56.46  ? 360 ILE E CB  1 
ATOM   7031  C CG1 . ILE E 1 153 ? -77.214  40.756  31.428  1.00 61.80  ? 360 ILE E CG1 1 
ATOM   7032  C CG2 . ILE E 1 153 ? -76.714  42.958  30.670  1.00 64.76  ? 360 ILE E CG2 1 
ATOM   7033  C CD1 . ILE E 1 153 ? -75.875  40.229  31.768  1.00 65.72  ? 360 ILE E CD1 1 
ATOM   7034  N N   . PHE E 1 154 ? -79.575  43.983  29.861  1.00 60.17  ? 361 PHE E N   1 
ATOM   7035  C CA  . PHE E 1 154 ? -80.399  44.945  30.624  1.00 57.50  ? 361 PHE E CA  1 
ATOM   7036  C C   . PHE E 1 154 ? -81.850  44.504  30.531  1.00 60.47  ? 361 PHE E C   1 
ATOM   7037  O O   . PHE E 1 154 ? -82.501  44.433  31.568  1.00 58.05  ? 361 PHE E O   1 
ATOM   7038  C CB  . PHE E 1 154 ? -80.201  46.372  30.114  1.00 61.73  ? 361 PHE E CB  1 
ATOM   7039  N N   . GLU E 1 155 ? -82.316  44.209  29.322  1.00 56.80  ? 362 GLU E N   1 
ATOM   7040  C CA  . GLU E 1 155 ? -83.683  43.757  29.122  1.00 58.82  ? 362 GLU E CA  1 
ATOM   7041  C C   . GLU E 1 155 ? -84.018  42.607  30.064  1.00 57.97  ? 362 GLU E C   1 
ATOM   7042  O O   . GLU E 1 155 ? -85.129  42.545  30.604  1.00 52.63  ? 362 GLU E O   1 
ATOM   7043  C CB  . GLU E 1 155 ? -83.872  43.343  27.661  1.00 65.45  ? 362 GLU E CB  1 
ATOM   7044  C CG  . GLU E 1 155 ? -84.456  44.438  26.772  1.00 71.81  ? 362 GLU E CG  1 
ATOM   7045  C CD  . GLU E 1 155 ? -85.031  43.886  25.474  1.00 80.25  ? 362 GLU E CD  1 
ATOM   7046  O OE1 . GLU E 1 155 ? -85.571  42.751  25.490  1.00 77.34  ? 362 GLU E OE1 1 
ATOM   7047  O OE2 . GLU E 1 155 ? -84.960  44.598  24.447  1.00 81.87  ? 362 GLU E OE2 1 
ATOM   7048  N N   . SER E 1 156 ? -83.052  41.701  30.286  1.00 55.90  ? 363 SER E N   1 
ATOM   7049  C CA  . SER E 1 156 ? -83.210  40.632  31.267  1.00 54.97  ? 363 SER E CA  1 
ATOM   7050  C C   . SER E 1 156 ? -83.420  41.179  32.677  1.00 54.20  ? 363 SER E C   1 
ATOM   7051  O O   . SER E 1 156 ? -84.406  40.846  33.344  1.00 51.58  ? 363 SER E O   1 
ATOM   7052  C CB  . SER E 1 156 ? -81.990  39.716  31.237  1.00 55.91  ? 363 SER E CB  1 
ATOM   7053  O OG  . SER E 1 156 ? -82.353  38.423  31.679  1.00 57.50  ? 363 SER E OG  1 
ATOM   7054  N N   . PHE E 1 157 ? -82.477  41.991  33.166  1.00 54.21  ? 364 PHE E N   1 
ATOM   7055  C CA  . PHE E 1 157 ? -82.621  42.563  34.503  1.00 51.18  ? 364 PHE E CA  1 
ATOM   7056  C C   . PHE E 1 157 ? -83.917  43.359  34.639  1.00 51.86  ? 364 PHE E C   1 
ATOM   7057  O O   . PHE E 1 157 ? -84.526  43.373  35.713  1.00 50.16  ? 364 PHE E O   1 
ATOM   7058  C CB  . PHE E 1 157 ? -81.417  43.443  34.823  1.00 51.92  ? 364 PHE E CB  1 
ATOM   7059  C CG  . PHE E 1 157 ? -80.266  42.706  35.460  1.00 56.26  ? 364 PHE E CG  1 
ATOM   7060  C CD1 . PHE E 1 157 ? -80.217  42.524  36.833  1.00 50.96  ? 364 PHE E CD1 1 
ATOM   7061  C CD2 . PHE E 1 157 ? -79.228  42.211  34.690  1.00 55.44  ? 364 PHE E CD2 1 
ATOM   7062  C CE1 . PHE E 1 157 ? -79.169  41.866  37.425  1.00 50.26  ? 364 PHE E CE1 1 
ATOM   7063  C CE2 . PHE E 1 157 ? -78.169  41.554  35.280  1.00 57.69  ? 364 PHE E CE2 1 
ATOM   7064  C CZ  . PHE E 1 157 ? -78.139  41.386  36.655  1.00 56.07  ? 364 PHE E CZ  1 
ATOM   7065  N N   . VAL E 1 158 ? -84.365  44.016  33.566  1.00 48.20  ? 365 VAL E N   1 
ATOM   7066  C CA  . VAL E 1 158 ? -85.653  44.696  33.621  1.00 49.67  ? 365 VAL E CA  1 
ATOM   7067  C C   . VAL E 1 158 ? -86.789  43.699  33.838  1.00 49.91  ? 365 VAL E C   1 
ATOM   7068  O O   . VAL E 1 158 ? -87.746  43.978  34.572  1.00 53.17  ? 365 VAL E O   1 
ATOM   7069  C CB  . VAL E 1 158 ? -85.862  45.533  32.349  1.00 47.39  ? 365 VAL E CB  1 
ATOM   7070  C CG1 . VAL E 1 158 ? -87.266  46.123  32.321  1.00 27.40  ? 365 VAL E CG1 1 
ATOM   7071  C CG2 . VAL E 1 158 ? -84.832  46.633  32.300  1.00 50.45  ? 365 VAL E CG2 1 
ATOM   7072  N N   . ASP E 1 159 ? -86.699  42.520  33.215  1.00 48.60  ? 366 ASP E N   1 
ATOM   7073  C CA  . ASP E 1 159 ? -87.733  41.503  33.376  1.00 53.94  ? 366 ASP E CA  1 
ATOM   7074  C C   . ASP E 1 159 ? -87.736  40.931  34.791  1.00 57.40  ? 366 ASP E C   1 
ATOM   7075  O O   . ASP E 1 159 ? -88.788  40.854  35.437  1.00 55.20  ? 366 ASP E O   1 
ATOM   7076  C CB  . ASP E 1 159 ? -87.527  40.391  32.349  1.00 61.71  ? 366 ASP E CB  1 
ATOM   7077  C CG  . ASP E 1 159 ? -88.636  39.359  32.379  1.00 72.46  ? 366 ASP E CG  1 
ATOM   7078  O OD1 . ASP E 1 159 ? -89.818  39.768  32.312  1.00 69.86  ? 366 ASP E OD1 1 
ATOM   7079  O OD2 . ASP E 1 159 ? -88.323  38.147  32.479  1.00 75.37  ? 366 ASP E OD2 1 
ATOM   7080  N N   . TYR E 1 160 ? -86.559  40.513  35.274  1.00 55.22  ? 367 TYR E N   1 
ATOM   7081  C CA  . TYR E 1 160 ? -86.363  40.078  36.653  1.00 52.46  ? 367 TYR E CA  1 
ATOM   7082  C C   . TYR E 1 160 ? -87.117  40.940  37.654  1.00 53.05  ? 367 TYR E C   1 
ATOM   7083  O O   . TYR E 1 160 ? -87.891  40.437  38.471  1.00 58.64  ? 367 TYR E O   1 
ATOM   7084  C CB  . TYR E 1 160 ? -84.863  40.084  36.966  1.00 52.97  ? 367 TYR E CB  1 
ATOM   7085  C CG  . TYR E 1 160 ? -84.464  39.192  38.117  1.00 55.46  ? 367 TYR E CG  1 
ATOM   7086  C CD1 . TYR E 1 160 ? -84.815  39.510  39.423  1.00 61.56  ? 367 TYR E CD1 1 
ATOM   7087  C CD2 . TYR E 1 160 ? -83.727  38.032  37.906  1.00 53.05  ? 367 TYR E CD2 1 
ATOM   7088  C CE1 . TYR E 1 160 ? -84.447  38.692  40.487  1.00 56.81  ? 367 TYR E CE1 1 
ATOM   7089  C CE2 . TYR E 1 160 ? -83.362  37.207  38.966  1.00 49.34  ? 367 TYR E CE2 1 
ATOM   7090  C CZ  . TYR E 1 160 ? -83.724  37.547  40.253  1.00 52.24  ? 367 TYR E CZ  1 
ATOM   7091  O OH  . TYR E 1 160 ? -83.378  36.739  41.311  1.00 53.77  ? 367 TYR E OH  1 
ATOM   7092  N N   . VAL E 1 161 ? -86.918  42.254  37.613  1.00 49.01  ? 368 VAL E N   1 
ATOM   7093  C CA  . VAL E 1 161 ? -87.549  43.082  38.626  1.00 56.94  ? 368 VAL E CA  1 
ATOM   7094  C C   . VAL E 1 161 ? -88.967  43.471  38.266  1.00 57.81  ? 368 VAL E C   1 
ATOM   7095  O O   . VAL E 1 161 ? -89.616  44.185  39.045  1.00 58.91  ? 368 VAL E O   1 
ATOM   7096  C CB  . VAL E 1 161 ? -86.715  44.336  38.895  1.00 59.80  ? 368 VAL E CB  1 
ATOM   7097  C CG1 . VAL E 1 161 ? -85.271  43.917  39.134  1.00 65.07  ? 368 VAL E CG1 1 
ATOM   7098  C CG2 . VAL E 1 161 ? -86.824  45.257  37.714  1.00 62.18  ? 368 VAL E CG2 1 
ATOM   7099  N N   . ALA E 1 162 ? -89.485  42.991  37.140  1.00 53.87  ? 369 ALA E N   1 
ATOM   7100  C CA  . ALA E 1 162 ? -90.823  43.379  36.718  1.00 54.33  ? 369 ALA E CA  1 
ATOM   7101  C C   . ALA E 1 162 ? -91.893  42.729  37.584  1.00 49.20  ? 369 ALA E C   1 
ATOM   7102  O O   . ALA E 1 162 ? -91.775  41.572  37.988  1.00 61.16  ? 369 ALA E O   1 
ATOM   7103  C CB  . ALA E 1 162 ? -91.054  43.007  35.254  1.00 56.28  ? 369 ALA E CB  1 
ATOM   7104  N N   . VAL E 1 163 ? -92.963  43.479  37.831  1.00 48.83  ? 370 VAL E N   1 
ATOM   7105  C CA  . VAL E 1 163 ? -94.073  43.009  38.651  1.00 50.64  ? 370 VAL E CA  1 
ATOM   7106  C C   . VAL E 1 163 ? -94.874  41.958  37.894  1.00 53.30  ? 370 VAL E C   1 
ATOM   7107  O O   . VAL E 1 163 ? -95.421  42.230  36.823  1.00 59.51  ? 370 VAL E O   1 
ATOM   7108  C CB  . VAL E 1 163 ? -94.970  44.182  39.045  1.00 46.74  ? 370 VAL E CB  1 
ATOM   7109  C CG1 . VAL E 1 163 ? -96.157  43.690  39.879  1.00 48.26  ? 370 VAL E CG1 1 
ATOM   7110  C CG2 . VAL E 1 163 ? -94.142  45.261  39.737  1.00 32.22  ? 370 VAL E CG2 1 
ATOM   7111  N N   . GLU E 1 164 ? -94.974  40.760  38.459  1.00 56.92  ? 371 GLU E N   1 
ATOM   7112  C CA  . GLU E 1 164 ? -95.844  39.727  37.919  1.00 50.23  ? 371 GLU E CA  1 
ATOM   7113  C C   . GLU E 1 164 ? -97.182  39.726  38.633  1.00 61.36  ? 371 GLU E C   1 
ATOM   7114  O O   . GLU E 1 164 ? -97.389  40.394  39.653  1.00 60.69  ? 371 GLU E O   1 
ATOM   7115  C CB  . GLU E 1 164 ? -95.247  38.334  38.056  1.00 59.38  ? 371 GLU E CB  1 
ATOM   7116  C CG  . GLU E 1 164 ? -93.763  38.253  38.114  1.00 66.95  ? 371 GLU E CG  1 
ATOM   7117  C CD  . GLU E 1 164 ? -93.327  36.813  38.105  1.00 68.56  ? 371 GLU E CD  1 
ATOM   7118  O OE1 . GLU E 1 164 ? -92.306  36.492  38.751  1.00 71.99  ? 371 GLU E OE1 1 
ATOM   7119  O OE2 . GLU E 1 164 ? -94.025  36.004  37.453  1.00 68.49  ? 371 GLU E OE2 1 
ATOM   7120  N N   . GLN E 1 165 ? -98.091  38.922  38.090  1.00 66.09  ? 372 GLN E N   1 
ATOM   7121  C CA  . GLN E 1 165 ? -99.412  38.714  38.659  1.00 61.59  ? 372 GLN E CA  1 
ATOM   7122  C C   . GLN E 1 165 ? -99.470  37.316  39.257  1.00 63.29  ? 372 GLN E C   1 
ATOM   7123  O O   . GLN E 1 165 ? -98.924  36.367  38.681  1.00 65.07  ? 372 GLN E O   1 
ATOM   7124  C CB  . GLN E 1 165 ? -100.508 38.883  37.596  1.00 59.39  ? 372 GLN E CB  1 
ATOM   7125  C CG  . GLN E 1 165 ? -100.432 40.186  36.777  1.00 55.70  ? 372 GLN E CG  1 
ATOM   7126  C CD  . GLN E 1 165 ? -100.495 41.430  37.650  1.00 68.56  ? 372 GLN E CD  1 
ATOM   7127  O OE1 . GLN E 1 165 ? -101.401 41.595  38.488  1.00 68.36  ? 372 GLN E OE1 1 
ATOM   7128  N NE2 . GLN E 1 165 ? -99.519  42.314  37.467  1.00 64.34  ? 372 GLN E NE2 1 
ATOM   7129  N N   . LEU E 1 166 ? -100.112 37.201  40.420  1.00 57.36  ? 373 LEU E N   1 
ATOM   7130  C CA  . LEU E 1 166 ? -100.381 35.920  41.069  1.00 53.04  ? 373 LEU E CA  1 
ATOM   7131  C C   . LEU E 1 166 ? -101.891 35.718  41.055  1.00 52.04  ? 373 LEU E C   1 
ATOM   7132  O O   . LEU E 1 166 ? -102.595 36.142  41.971  1.00 50.83  ? 373 LEU E O   1 
ATOM   7133  C CB  . LEU E 1 166 ? -99.821  35.884  42.491  1.00 54.31  ? 373 LEU E CB  1 
ATOM   7134  C CG  . LEU E 1 166 ? -98.302  36.049  42.640  1.00 50.76  ? 373 LEU E CG  1 
ATOM   7135  C CD1 . LEU E 1 166 ? -97.885  35.943  44.104  1.00 48.47  ? 373 LEU E CD1 1 
ATOM   7136  C CD2 . LEU E 1 166 ? -97.554  35.037  41.813  1.00 47.28  ? 373 LEU E CD2 1 
ATOM   7137  N N   . ASP E 1 167 ? -102.376 35.041  40.013  1.00 56.62  ? 374 ASP E N   1 
ATOM   7138  C CA  . ASP E 1 167 ? -103.799 34.822  39.791  1.00 59.39  ? 374 ASP E CA  1 
ATOM   7139  C C   . ASP E 1 167 ? -104.009 33.421  39.215  1.00 56.72  ? 374 ASP E C   1 
ATOM   7140  O O   . ASP E 1 167 ? -103.065 32.746  38.797  1.00 55.90  ? 374 ASP E O   1 
ATOM   7141  C CB  . ASP E 1 167 ? -104.383 35.908  38.870  1.00 51.62  ? 374 ASP E CB  1 
ATOM   7142  C CG  . ASP E 1 167 ? -103.643 36.013  37.543  1.00 61.01  ? 374 ASP E CG  1 
ATOM   7143  O OD1 . ASP E 1 167 ? -102.955 35.044  37.167  1.00 63.02  ? 374 ASP E OD1 1 
ATOM   7144  O OD2 . ASP E 1 167 ? -103.757 37.053  36.856  1.00 62.20  ? 374 ASP E OD2 1 
ATOM   7145  N N   . GLY E 1 168 ? -105.266 32.987  39.186  1.00 55.31  ? 375 GLY E N   1 
ATOM   7146  C CA  . GLY E 1 168 ? -105.606 31.682  38.647  1.00 51.10  ? 375 GLY E CA  1 
ATOM   7147  C C   . GLY E 1 168 ? -105.168 30.510  39.502  1.00 54.09  ? 375 GLY E C   1 
ATOM   7148  O O   . GLY E 1 168 ? -105.508 30.406  40.686  1.00 54.55  ? 375 GLY E O   1 
ATOM   7149  N N   . ASP E 1 169 ? -104.409 29.605  38.893  1.00 52.33  ? 376 ASP E N   1 
ATOM   7150  C CA  . ASP E 1 169 ? -103.774 28.495  39.594  1.00 51.93  ? 376 ASP E CA  1 
ATOM   7151  C C   . ASP E 1 169 ? -102.642 28.929  40.522  1.00 56.27  ? 376 ASP E C   1 
ATOM   7152  O O   . ASP E 1 169 ? -102.024 28.073  41.169  1.00 54.93  ? 376 ASP E O   1 
ATOM   7153  C CB  . ASP E 1 169 ? -103.214 27.509  38.576  1.00 54.87  ? 376 ASP E CB  1 
ATOM   7154  C CG  . ASP E 1 169 ? -103.260 26.121  39.068  1.00 53.75  ? 376 ASP E CG  1 
ATOM   7155  O OD1 . ASP E 1 169 ? -104.112 25.896  39.941  1.00 54.87  ? 376 ASP E OD1 1 
ATOM   7156  O OD2 . ASP E 1 169 ? -102.455 25.281  38.606  1.00 53.77  ? 376 ASP E OD2 1 
ATOM   7157  N N   . ASN E 1 170 ? -102.342 30.218  40.591  1.00 50.41  ? 377 ASN E N   1 
ATOM   7158  C CA  . ASN E 1 170 ? -101.135 30.672  41.249  1.00 46.31  ? 377 ASN E CA  1 
ATOM   7159  C C   . ASN E 1 170 ? -101.438 31.867  42.116  1.00 51.18  ? 377 ASN E C   1 
ATOM   7160  O O   . ASN E 1 170 ? -100.609 32.774  42.249  1.00 49.59  ? 377 ASN E O   1 
ATOM   7161  C CB  . ASN E 1 170 ? -100.065 30.990  40.220  1.00 46.67  ? 377 ASN E CB  1 
ATOM   7162  C CG  . ASN E 1 170 ? -99.587  29.760  39.513  1.00 48.70  ? 377 ASN E CG  1 
ATOM   7163  O OD1 . ASN E 1 170 ? -98.794  28.994  40.057  1.00 52.93  ? 377 ASN E OD1 1 
ATOM   7164  N ND2 . ASN E 1 170 ? -100.097 29.531  38.312  1.00 45.46  ? 377 ASN E ND2 1 
ATOM   7165  N N   . LYS E 1 171 ? -102.635 31.879  42.698  1.00 54.62  ? 378 LYS E N   1 
ATOM   7166  C CA  . LYS E 1 171 ? -103.032 32.879  43.678  1.00 53.49  ? 378 LYS E CA  1 
ATOM   7167  C C   . LYS E 1 171 ? -102.146 32.775  44.906  1.00 49.00  ? 378 LYS E C   1 
ATOM   7168  O O   . LYS E 1 171 ? -101.320 31.868  44.991  1.00 61.07  ? 378 LYS E O   1 
ATOM   7169  C CB  . LYS E 1 171 ? -104.504 32.708  44.054  1.00 55.01  ? 378 LYS E CB  1 
ATOM   7170  C CG  . LYS E 1 171 ? -105.464 32.691  42.877  1.00 58.15  ? 378 LYS E CG  1 
ATOM   7171  C CD  . LYS E 1 171 ? -106.866 32.238  43.312  1.00 66.61  ? 378 LYS E CD  1 
ATOM   7172  C CE  . LYS E 1 171 ? -107.842 33.416  43.496  1.00 74.50  ? 378 LYS E CE  1 
ATOM   7173  N NZ  . LYS E 1 171 ? -109.279 33.013  43.720  1.00 78.69  ? 378 LYS E NZ  1 
ATOM   7174  N N   . TYR E 1 172 ? -102.303 33.673  45.862  1.00 48.93  ? 379 TYR E N   1 
ATOM   7175  C CA  . TYR E 1 172 ? -101.397 33.758  46.993  1.00 49.85  ? 379 TYR E CA  1 
ATOM   7176  C C   . TYR E 1 172 ? -102.175 33.534  48.285  1.00 54.01  ? 379 TYR E C   1 
ATOM   7177  O O   . TYR E 1 172 ? -103.310 34.004  48.421  1.00 51.61  ? 379 TYR E O   1 
ATOM   7178  C CB  . TYR E 1 172 ? -100.686 35.124  46.974  1.00 48.20  ? 379 TYR E CB  1 
ATOM   7179  C CG  . TYR E 1 172 ? -100.023 35.525  48.264  1.00 53.07  ? 379 TYR E CG  1 
ATOM   7180  C CD1 . TYR E 1 172 ? -98.789  35.009  48.627  1.00 49.82  ? 379 TYR E CD1 1 
ATOM   7181  C CD2 . TYR E 1 172 ? -100.644 36.429  49.134  1.00 50.64  ? 379 TYR E CD2 1 
ATOM   7182  C CE1 . TYR E 1 172 ? -98.192  35.379  49.820  1.00 51.12  ? 379 TYR E CE1 1 
ATOM   7183  C CE2 . TYR E 1 172 ? -100.067 36.791  50.322  1.00 43.21  ? 379 TYR E CE2 1 
ATOM   7184  C CZ  . TYR E 1 172 ? -98.836  36.272  50.660  1.00 52.05  ? 379 TYR E CZ  1 
ATOM   7185  O OH  . TYR E 1 172 ? -98.235  36.640  51.846  1.00 58.37  ? 379 TYR E OH  1 
ATOM   7186  N N   . ASP E 1 173 ? -101.569 32.810  49.239  1.00 52.83  ? 380 ASP E N   1 
ATOM   7187  C CA  . ASP E 1 173 ? -102.240 32.477  50.505  1.00 51.26  ? 380 ASP E CA  1 
ATOM   7188  C C   . ASP E 1 173 ? -102.049 33.638  51.473  1.00 54.82  ? 380 ASP E C   1 
ATOM   7189  O O   . ASP E 1 173 ? -101.010 33.754  52.127  1.00 55.11  ? 380 ASP E O   1 
ATOM   7190  C CB  . ASP E 1 173 ? -101.721 31.157  51.084  1.00 48.29  ? 380 ASP E CB  1 
ATOM   7191  C CG  . ASP E 1 173 ? -102.216 30.881  52.527  1.00 56.85  ? 380 ASP E CG  1 
ATOM   7192  O OD1 . ASP E 1 173 ? -103.294 31.371  52.939  1.00 63.06  ? 380 ASP E OD1 1 
ATOM   7193  O OD2 . ASP E 1 173 ? -101.527 30.150  53.267  1.00 57.15  ? 380 ASP E OD2 1 
ATOM   7194  N N   . ALA E 1 174 ? -103.062 34.494  51.583  1.00 54.64  ? 381 ALA E N   1 
ATOM   7195  C CA  . ALA E 1 174 ? -102.988 35.659  52.471  1.00 54.03  ? 381 ALA E CA  1 
ATOM   7196  C C   . ALA E 1 174 ? -103.775 35.423  53.761  1.00 57.35  ? 381 ALA E C   1 
ATOM   7197  O O   . ALA E 1 174 ? -104.749 36.115  54.063  1.00 60.50  ? 381 ALA E O   1 
ATOM   7198  C CB  . ALA E 1 174 ? -103.482 36.907  51.746  1.00 52.05  ? 381 ALA E CB  1 
ATOM   7199  N N   . GLY E 1 175 ? -103.347 34.415  54.519  1.00 58.93  ? 382 GLY E N   1 
ATOM   7200  C CA  . GLY E 1 175 ? -103.818 34.264  55.892  1.00 60.59  ? 382 GLY E CA  1 
ATOM   7201  C C   . GLY E 1 175 ? -105.314 34.020  55.991  1.00 65.94  ? 382 GLY E C   1 
ATOM   7202  O O   . GLY E 1 175 ? -105.881 33.170  55.294  1.00 70.74  ? 382 GLY E O   1 
ATOM   7203  N N   . GLU E 1 176 ? -105.970 34.782  56.873  1.00 65.56  ? 383 GLU E N   1 
ATOM   7204  C CA  . GLU E 1 176 ? -107.411 34.666  57.059  1.00 63.86  ? 383 GLU E CA  1 
ATOM   7205  C C   . GLU E 1 176 ? -108.200 34.972  55.788  1.00 68.78  ? 383 GLU E C   1 
ATOM   7206  O O   . GLU E 1 176 ? -109.394 34.637  55.729  1.00 68.52  ? 383 GLU E O   1 
ATOM   7207  C CB  . GLU E 1 176 ? -107.866 35.583  58.200  1.00 48.97  ? 383 GLU E CB  1 
ATOM   7208  N N   . HIS E 1 177 ? -107.550 35.547  54.783  1.00 60.96  ? 384 HIS E N   1 
ATOM   7209  C CA  . HIS E 1 177 ? -108.237 35.831  53.501  1.00 64.01  ? 384 HIS E CA  1 
ATOM   7210  C C   . HIS E 1 177 ? -108.073 34.652  52.543  1.00 66.10  ? 384 HIS E C   1 
ATOM   7211  O O   . HIS E 1 177 ? -108.620 34.735  51.438  1.00 62.53  ? 384 HIS E O   1 
ATOM   7212  C CB  . HIS E 1 177 ? -107.711 37.134  52.899  1.00 58.62  ? 384 HIS E CB  1 
ATOM   7213  C CG  . HIS E 1 177 ? -107.602 38.263  53.864  1.00 70.10  ? 384 HIS E CG  1 
ATOM   7214  N ND1 . HIS E 1 177 ? -108.698 38.994  54.266  1.00 74.53  ? 384 HIS E ND1 1 
ATOM   7215  C CD2 . HIS E 1 177 ? -106.536 38.801  54.492  1.00 67.94  ? 384 HIS E CD2 1 
ATOM   7216  C CE1 . HIS E 1 177 ? -108.313 39.928  55.108  1.00 66.95  ? 384 HIS E CE1 1 
ATOM   7217  N NE2 . HIS E 1 177 ? -106.992 39.831  55.262  1.00 62.78  ? 384 HIS E NE2 1 
ATOM   7218  N N   . GLY E 1 178 ? -107.374 33.591  52.954  1.00 55.01  ? 385 GLY E N   1 
ATOM   7219  C CA  . GLY E 1 178 ? -107.116 32.478  52.069  1.00 54.25  ? 385 GLY E CA  1 
ATOM   7220  C C   . GLY E 1 178 ? -106.454 32.916  50.778  1.00 54.48  ? 385 GLY E C   1 
ATOM   7221  O O   . GLY E 1 178 ? -105.646 33.857  50.739  1.00 52.69  ? 385 GLY E O   1 
ATOM   7222  N N   . LEU E 1 179 ? -106.788 32.218  49.696  1.00 53.58  ? 386 LEU E N   1 
ATOM   7223  C CA  . LEU E 1 179 ? -106.121 32.481  48.426  1.00 56.98  ? 386 LEU E CA  1 
ATOM   7224  C C   . LEU E 1 179 ? -106.657 33.773  47.828  1.00 60.54  ? 386 LEU E C   1 
ATOM   7225  O O   . LEU E 1 179 ? -107.851 34.070  47.922  1.00 66.47  ? 386 LEU E O   1 
ATOM   7226  C CB  . LEU E 1 179 ? -106.303 31.322  47.441  1.00 60.65  ? 386 LEU E CB  1 
ATOM   7227  C CG  . LEU E 1 179 ? -105.636 29.974  47.762  1.00 57.71  ? 386 LEU E CG  1 
ATOM   7228  C CD1 . LEU E 1 179 ? -105.646 29.060  46.554  1.00 50.52  ? 386 LEU E CD1 1 
ATOM   7229  C CD2 . LEU E 1 179 ? -104.225 30.150  48.280  1.00 53.64  ? 386 LEU E CD2 1 
ATOM   7230  N N   . GLN E 1 180 ? -105.761 34.551  47.226  1.00 56.47  ? 387 GLN E N   1 
ATOM   7231  C CA  . GLN E 1 180 ? -106.070 35.906  46.812  1.00 47.86  ? 387 GLN E CA  1 
ATOM   7232  C C   . GLN E 1 180 ? -105.265 36.220  45.570  1.00 53.42  ? 387 GLN E C   1 
ATOM   7233  O O   . GLN E 1 180 ? -104.116 35.787  45.450  1.00 56.16  ? 387 GLN E O   1 
ATOM   7234  C CB  . GLN E 1 180 ? -105.717 36.919  47.903  1.00 48.05  ? 387 GLN E CB  1 
ATOM   7235  C CG  . GLN E 1 180 ? -106.565 36.835  49.130  1.00 52.05  ? 387 GLN E CG  1 
ATOM   7236  C CD  . GLN E 1 180 ? -107.928 37.425  48.895  1.00 57.85  ? 387 GLN E CD  1 
ATOM   7237  O OE1 . GLN E 1 180 ? -108.115 38.249  47.991  1.00 58.67  ? 387 GLN E OE1 1 
ATOM   7238  N NE2 . GLN E 1 180 ? -108.892 37.013  49.701  1.00 58.57  ? 387 GLN E NE2 1 
ATOM   7239  N N   . GLU E 1 181 ? -105.862 36.978  44.654  1.00 58.18  ? 388 GLU E N   1 
ATOM   7240  C CA  . GLU E 1 181 ? -105.071 37.591  43.594  1.00 55.15  ? 388 GLU E CA  1 
ATOM   7241  C C   . GLU E 1 181 ? -104.079 38.575  44.206  1.00 54.07  ? 388 GLU E C   1 
ATOM   7242  O O   . GLU E 1 181 ? -104.405 39.313  45.143  1.00 56.15  ? 388 GLU E O   1 
ATOM   7243  C CB  . GLU E 1 181 ? -105.977 38.300  42.594  1.00 57.05  ? 388 GLU E CB  1 
ATOM   7244  C CG  . GLU E 1 181 ? -107.153 37.473  42.155  1.00 66.96  ? 388 GLU E CG  1 
ATOM   7245  C CD  . GLU E 1 181 ? -107.270 37.416  40.647  1.00 79.05  ? 388 GLU E CD  1 
ATOM   7246  O OE1 . GLU E 1 181 ? -107.367 38.511  40.035  1.00 74.25  ? 388 GLU E OE1 1 
ATOM   7247  O OE2 . GLU E 1 181 ? -107.251 36.282  40.082  1.00 79.39  ? 388 GLU E OE2 1 
ATOM   7248  N N   . ALA E 1 182 ? -102.856 38.575  43.687  1.00 52.07  ? 389 ALA E N   1 
ATOM   7249  C CA  . ALA E 1 182 ? -101.801 39.353  44.301  1.00 48.43  ? 389 ALA E CA  1 
ATOM   7250  C C   . ALA E 1 182 ? -100.760 39.679  43.251  1.00 47.25  ? 389 ALA E C   1 
ATOM   7251  O O   . ALA E 1 182 ? -100.707 39.057  42.191  1.00 48.03  ? 389 ALA E O   1 
ATOM   7252  C CB  . ALA E 1 182 ? -101.166 38.600  45.471  1.00 48.85  ? 389 ALA E CB  1 
ATOM   7253  N N   . GLU E 1 183 ? -99.939  40.680  43.558  1.00 53.89  ? 390 GLU E N   1 
ATOM   7254  C CA  . GLU E 1 183 ? -98.775  41.035  42.763  1.00 56.35  ? 390 GLU E CA  1 
ATOM   7255  C C   . GLU E 1 183 ? -97.510  40.668  43.525  1.00 51.46  ? 390 GLU E C   1 
ATOM   7256  O O   . GLU E 1 183 ? -97.465  40.715  44.758  1.00 47.12  ? 390 GLU E O   1 
ATOM   7257  C CB  . GLU E 1 183 ? -98.727  42.534  42.432  1.00 57.60  ? 390 GLU E CB  1 
ATOM   7258  C CG  . GLU E 1 183 ? -99.826  43.076  41.523  1.00 67.64  ? 390 GLU E CG  1 
ATOM   7259  C CD  . GLU E 1 183 ? -99.675  44.584  41.292  1.00 81.03  ? 390 GLU E CD  1 
ATOM   7260  O OE1 . GLU E 1 183 ? -99.205  45.275  42.229  1.00 77.93  ? 390 GLU E OE1 1 
ATOM   7261  O OE2 . GLU E 1 183 ? -100.015 45.070  40.184  1.00 81.15  ? 390 GLU E OE2 1 
ATOM   7262  N N   . LYS E 1 184 ? -96.485  40.317  42.750  1.00 49.52  ? 391 LYS E N   1 
ATOM   7263  C CA  . LYS E 1 184 ? -95.160  40.007  43.324  1.00 51.22  ? 391 LYS E CA  1 
ATOM   7264  C C   . LYS E 1 184 ? -94.091  40.717  42.504  1.00 49.79  ? 391 LYS E C   1 
ATOM   7265  O O   . LYS E 1 184 ? -94.135  40.625  41.278  1.00 51.85  ? 391 LYS E O   1 
ATOM   7266  C CB  . LYS E 1 184 ? -94.871  38.506  43.286  1.00 53.68  ? 391 LYS E CB  1 
ATOM   7267  C CG  . LYS E 1 184 ? -93.609  38.062  44.009  1.00 54.82  ? 391 LYS E CG  1 
ATOM   7268  C CD  . LYS E 1 184 ? -92.963  36.848  43.390  1.00 53.39  ? 391 LYS E CD  1 
ATOM   7269  C CE  . LYS E 1 184 ? -92.182  36.024  44.389  1.00 59.56  ? 391 LYS E CE  1 
ATOM   7270  N NZ  . LYS E 1 184 ? -90.818  35.715  43.904  1.00 52.82  ? 391 LYS E NZ  1 
ATOM   7271  N N   . GLY E 1 185 ? -93.186  41.424  43.164  1.00 41.47  ? 392 GLY E N   1 
ATOM   7272  C CA  . GLY E 1 185 ? -92.067  41.995  42.456  1.00 47.26  ? 392 GLY E CA  1 
ATOM   7273  C C   . GLY E 1 185 ? -90.781  41.736  43.211  1.00 52.80  ? 392 GLY E C   1 
ATOM   7274  O O   . GLY E 1 185 ? -90.751  41.798  44.443  1.00 52.90  ? 392 GLY E O   1 
ATOM   7275  N N   . VAL E 1 186 ? -89.718  41.443  42.515  1.00 49.69  ? 393 VAL E N   1 
ATOM   7276  C CA  . VAL E 1 186 ? -88.454  41.253  43.204  1.00 50.54  ? 393 VAL E CA  1 
ATOM   7277  C C   . VAL E 1 186 ? -87.594  42.493  42.993  1.00 53.05  ? 393 VAL E C   1 
ATOM   7278  O O   . VAL E 1 186 ? -87.728  43.202  41.987  1.00 60.97  ? 393 VAL E O   1 
ATOM   7279  C CB  . VAL E 1 186 ? -87.771  39.957  42.726  1.00 44.16  ? 393 VAL E CB  1 
ATOM   7280  C CG1 . VAL E 1 186 ? -86.533  39.712  43.513  1.00 50.44  ? 393 VAL E CG1 1 
ATOM   7281  C CG2 . VAL E 1 186 ? -88.721  38.806  42.931  1.00 47.56  ? 393 VAL E CG2 1 
ATOM   7282  N N   . LYS E 1 187 ? -86.762  42.809  43.987  1.00 49.00  ? 394 LYS E N   1 
ATOM   7283  C CA  . LYS E 1 187 ? -85.722  43.815  43.837  1.00 51.76  ? 394 LYS E CA  1 
ATOM   7284  C C   . LYS E 1 187 ? -84.490  43.352  44.586  1.00 51.61  ? 394 LYS E C   1 
ATOM   7285  O O   . LYS E 1 187 ? -84.561  42.476  45.451  1.00 52.99  ? 394 LYS E O   1 
ATOM   7286  C CB  . LYS E 1 187 ? -86.154  45.189  44.349  1.00 52.59  ? 394 LYS E CB  1 
ATOM   7287  C CG  . LYS E 1 187 ? -87.204  45.843  43.470  1.00 59.85  ? 394 LYS E CG  1 
ATOM   7288  C CD  . LYS E 1 187 ? -86.608  46.440  42.193  1.00 58.35  ? 394 LYS E CD  1 
ATOM   7289  C CE  . LYS E 1 187 ? -86.174  47.850  42.450  1.00 65.93  ? 394 LYS E CE  1 
ATOM   7290  N NZ  . LYS E 1 187 ? -87.218  48.526  43.275  1.00 73.13  ? 394 LYS E NZ  1 
ATOM   7291  N N   . PHE E 1 188 ? -83.371  43.989  44.266  1.00 55.54  ? 395 PHE E N   1 
ATOM   7292  C CA  . PHE E 1 188 ? -82.095  43.640  44.925  1.00 51.58  ? 395 PHE E CA  1 
ATOM   7293  C C   . PHE E 1 188 ? -81.781  44.665  46.005  1.00 53.73  ? 395 PHE E C   1 
ATOM   7294  O O   . PHE E 1 188 ? -82.041  45.850  45.807  1.00 56.23  ? 395 PHE E O   1 
ATOM   7295  C CB  . PHE E 1 188 ? -80.954  43.583  43.910  1.00 46.08  ? 395 PHE E CB  1 
ATOM   7296  C CG  . PHE E 1 188 ? -81.071  42.527  42.843  1.00 54.16  ? 395 PHE E CG  1 
ATOM   7297  C CD1 . PHE E 1 188 ? -81.689  42.800  41.635  1.00 58.88  ? 395 PHE E CD1 1 
ATOM   7298  C CD2 . PHE E 1 188 ? -80.532  41.268  43.035  1.00 56.81  ? 395 PHE E CD2 1 
ATOM   7299  C CE1 . PHE E 1 188 ? -81.787  41.830  40.651  1.00 55.69  ? 395 PHE E CE1 1 
ATOM   7300  C CE2 . PHE E 1 188 ? -80.632  40.298  42.052  1.00 50.44  ? 395 PHE E CE2 1 
ATOM   7301  C CZ  . PHE E 1 188 ? -81.255  40.582  40.861  1.00 52.38  ? 395 PHE E CZ  1 
ATOM   7302  N N   . LEU E 1 189 ? -81.295  44.199  47.142  1.00 46.95  ? 396 LEU E N   1 
ATOM   7303  C CA  . LEU E 1 189 ? -80.855  45.076  48.225  1.00 48.82  ? 396 LEU E CA  1 
ATOM   7304  C C   . LEU E 1 189 ? -79.352  45.324  48.171  1.00 51.86  ? 396 LEU E C   1 
ATOM   7305  O O   . LEU E 1 189 ? -78.902  46.472  48.201  1.00 54.23  ? 396 LEU E O   1 
ATOM   7306  C CB  . LEU E 1 189 ? -81.224  44.492  49.596  1.00 43.18  ? 396 LEU E CB  1 
ATOM   7307  C CG  . LEU E 1 189 ? -82.687  44.393  50.015  1.00 45.46  ? 396 LEU E CG  1 
ATOM   7308  C CD1 . LEU E 1 189 ? -82.767  43.952  51.451  1.00 44.86  ? 396 LEU E CD1 1 
ATOM   7309  C CD2 . LEU E 1 189 ? -83.390  45.712  49.837  1.00 48.37  ? 396 LEU E CD2 1 
ATOM   7310  N N   . THR E 1 190 ? -78.565  44.261  48.101  1.00 48.80  ? 397 THR E N   1 
ATOM   7311  C CA  . THR E 1 190 ? -77.140  44.355  47.857  1.00 47.91  ? 397 THR E CA  1 
ATOM   7312  C C   . THR E 1 190 ? -76.815  43.634  46.551  1.00 50.81  ? 397 THR E C   1 
ATOM   7313  O O   . THR E 1 190 ? -77.583  42.785  46.084  1.00 52.95  ? 397 THR E O   1 
ATOM   7314  C CB  . THR E 1 190 ? -76.332  43.778  49.045  1.00 47.82  ? 397 THR E CB  1 
ATOM   7315  O OG1 . THR E 1 190 ? -76.493  42.355  49.135  1.00 52.19  ? 397 THR E OG1 1 
ATOM   7316  C CG2 . THR E 1 190 ? -76.792  44.391  50.339  1.00 36.46  ? 397 THR E CG2 1 
ATOM   7317  N N   . LEU E 1 191 ? -75.690  44.012  45.936  1.00 46.49  ? 398 LEU E N   1 
ATOM   7318  C CA  . LEU E 1 191 ? -75.112  43.262  44.828  1.00 47.35  ? 398 LEU E CA  1 
ATOM   7319  C C   . LEU E 1 191 ? -73.663  42.962  45.192  1.00 51.94  ? 398 LEU E C   1 
ATOM   7320  O O   . LEU E 1 191 ? -72.942  43.864  45.658  1.00 53.09  ? 398 LEU E O   1 
ATOM   7321  C CB  . LEU E 1 191 ? -75.193  44.027  43.500  1.00 50.83  ? 398 LEU E CB  1 
ATOM   7322  C CG  . LEU E 1 191 ? -76.552  44.065  42.809  1.00 51.40  ? 398 LEU E CG  1 
ATOM   7323  C CD1 . LEU E 1 191 ? -76.704  45.286  41.924  1.00 52.69  ? 398 LEU E CD1 1 
ATOM   7324  C CD2 . LEU E 1 191 ? -76.686  42.821  41.992  1.00 55.18  ? 398 LEU E CD2 1 
ATOM   7325  N N   . PRO E 1 192 ? -73.193  41.735  44.989  1.00 53.22  ? 399 PRO E N   1 
ATOM   7326  C CA  . PRO E 1 192 ? -71.941  41.305  45.607  1.00 51.98  ? 399 PRO E CA  1 
ATOM   7327  C C   . PRO E 1 192 ? -70.756  41.790  44.799  1.00 50.60  ? 399 PRO E C   1 
ATOM   7328  O O   . PRO E 1 192 ? -70.915  42.127  43.619  1.00 54.09  ? 399 PRO E O   1 
ATOM   7329  C CB  . PRO E 1 192 ? -72.054  39.778  45.564  1.00 49.47  ? 399 PRO E CB  1 
ATOM   7330  C CG  . PRO E 1 192 ? -72.710  39.550  44.260  1.00 51.77  ? 399 PRO E CG  1 
ATOM   7331  C CD  . PRO E 1 192 ? -73.718  40.696  44.090  1.00 53.86  ? 399 PRO E CD  1 
ATOM   7332  N N   . PRO E 1 193 ? -69.557  41.843  45.392  1.00 52.00  ? 400 PRO E N   1 
ATOM   7333  C CA  . PRO E 1 193 ? -68.368  42.231  44.610  1.00 51.23  ? 400 PRO E CA  1 
ATOM   7334  C C   . PRO E 1 193 ? -68.227  41.450  43.331  1.00 55.06  ? 400 PRO E C   1 
ATOM   7335  O O   . PRO E 1 193 ? -67.976  42.042  42.278  1.00 59.57  ? 400 PRO E O   1 
ATOM   7336  C CB  . PRO E 1 193 ? -67.208  41.938  45.569  1.00 50.26  ? 400 PRO E CB  1 
ATOM   7337  C CG  . PRO E 1 193 ? -67.810  42.027  46.910  1.00 55.59  ? 400 PRO E CG  1 
ATOM   7338  C CD  . PRO E 1 193 ? -69.213  41.514  46.783  1.00 52.52  ? 400 PRO E CD  1 
ATOM   7339  N N   . VAL E 1 194 ? -68.423  40.136  43.396  1.00 57.51  ? 401 VAL E N   1 
ATOM   7340  C CA  . VAL E 1 194 ? -68.288  39.231  42.263  1.00 53.07  ? 401 VAL E CA  1 
ATOM   7341  C C   . VAL E 1 194 ? -69.674  38.711  41.925  1.00 53.83  ? 401 VAL E C   1 
ATOM   7342  O O   . VAL E 1 194 ? -70.292  38.005  42.729  1.00 62.02  ? 401 VAL E O   1 
ATOM   7343  C CB  . VAL E 1 194 ? -67.327  38.086  42.585  1.00 52.29  ? 401 VAL E CB  1 
ATOM   7344  C CG1 . VAL E 1 194 ? -66.864  37.435  41.312  1.00 55.27  ? 401 VAL E CG1 1 
ATOM   7345  C CG2 . VAL E 1 194 ? -66.165  38.622  43.395  1.00 47.43  ? 401 VAL E CG2 1 
ATOM   7346  N N   . LEU E 1 195 ? -70.168  39.089  40.745  1.00 54.16  ? 402 LEU E N   1 
ATOM   7347  C CA  . LEU E 1 195 ? -71.535  38.706  40.316  1.00 50.71  ? 402 LEU E CA  1 
ATOM   7348  C C   . LEU E 1 195 ? -71.498  37.505  39.374  1.00 50.64  ? 402 LEU E C   1 
ATOM   7349  O O   . LEU E 1 195 ? -70.855  37.600  38.333  1.00 48.77  ? 402 LEU E O   1 
ATOM   7350  C CB  . LEU E 1 195 ? -72.177  39.905  39.615  1.00 50.62  ? 402 LEU E CB  1 
ATOM   7351  C CG  . LEU E 1 195 ? -73.488  40.403  40.207  1.00 52.94  ? 402 LEU E CG  1 
ATOM   7352  C CD1 . LEU E 1 195 ? -74.272  41.165  39.159  1.00 46.05  ? 402 LEU E CD1 1 
ATOM   7353  C CD2 . LEU E 1 195 ? -74.310  39.247  40.741  1.00 48.47  ? 402 LEU E CD2 1 
ATOM   7354  N N   . HIS E 1 196 ? -72.188  36.429  39.741  1.00 50.52  ? 403 HIS E N   1 
ATOM   7355  C CA  . HIS E 1 196 ? -72.299  35.230  38.878  1.00 43.35  ? 403 HIS E CA  1 
ATOM   7356  C C   . HIS E 1 196 ? -73.683  35.225  38.242  1.00 48.42  ? 403 HIS E C   1 
ATOM   7357  O O   . HIS E 1 196 ? -74.668  35.222  38.979  1.00 48.79  ? 403 HIS E O   1 
ATOM   7358  C CB  . HIS E 1 196 ? -72.044  33.951  39.676  1.00 47.05  ? 403 HIS E CB  1 
ATOM   7359  C CG  . HIS E 1 196 ? -70.612  33.635  39.945  1.00 49.51  ? 403 HIS E CG  1 
ATOM   7360  N ND1 . HIS E 1 196 ? -69.594  34.537  39.737  1.00 50.99  ? 403 HIS E ND1 1 
ATOM   7361  C CD2 . HIS E 1 196 ? -70.030  32.513  40.416  1.00 52.86  ? 403 HIS E CD2 1 
ATOM   7362  C CE1 . HIS E 1 196 ? -68.448  33.983  40.064  1.00 47.13  ? 403 HIS E CE1 1 
ATOM   7363  N NE2 . HIS E 1 196 ? -68.688  32.743  40.480  1.00 45.67  ? 403 HIS E NE2 1 
ATOM   7364  N N   . LEU E 1 197 ? -73.737  35.256  36.919  1.00 46.05  ? 404 LEU E N   1 
ATOM   7365  C CA  . LEU E 1 197 ? -74.986  35.280  36.182  1.00 45.56  ? 404 LEU E CA  1 
ATOM   7366  C C   . LEU E 1 197 ? -75.080  33.987  35.393  1.00 50.61  ? 404 LEU E C   1 
ATOM   7367  O O   . LEU E 1 197 ? -74.154  33.635  34.650  1.00 50.09  ? 404 LEU E O   1 
ATOM   7368  C CB  . LEU E 1 197 ? -75.063  36.503  35.269  1.00 46.19  ? 404 LEU E CB  1 
ATOM   7369  C CG  . LEU E 1 197 ? -74.797  37.846  35.965  1.00 45.47  ? 404 LEU E CG  1 
ATOM   7370  C CD1 . LEU E 1 197 ? -74.732  38.962  34.957  1.00 48.54  ? 404 LEU E CD1 1 
ATOM   7371  C CD2 . LEU E 1 197 ? -75.854  38.139  36.990  1.00 43.48  ? 404 LEU E CD2 1 
ATOM   7372  N N   . GLN E 1 198 ? -76.180  33.273  35.596  1.00 46.42  ? 405 GLN E N   1 
ATOM   7373  C CA  . GLN E 1 198 ? -76.424  32.035  34.831  1.00 43.28  ? 405 GLN E CA  1 
ATOM   7374  C C   . GLN E 1 198 ? -77.447  32.373  33.761  1.00 50.35  ? 405 GLN E C   1 
ATOM   7375  O O   . GLN E 1 198 ? -78.584  32.700  34.107  1.00 51.65  ? 405 GLN E O   1 
ATOM   7376  C CB  . GLN E 1 198 ? -76.930  30.920  35.736  1.00 44.97  ? 405 GLN E CB  1 
ATOM   7377  C CG  . GLN E 1 198 ? -76.973  29.569  35.048  1.00 50.03  ? 405 GLN E CG  1 
ATOM   7378  C CD  . GLN E 1 198 ? -77.915  28.626  35.750  1.00 56.29  ? 405 GLN E CD  1 
ATOM   7379  O OE1 . GLN E 1 198 ? -78.305  27.595  35.220  1.00 50.67  ? 405 GLN E OE1 1 
ATOM   7380  N NE2 . GLN E 1 198 ? -78.283  28.973  36.968  1.00 51.69  ? 405 GLN E NE2 1 
ATOM   7381  N N   . LEU E 1 199 ? -77.023  32.311  32.507  1.00 46.79  ? 406 LEU E N   1 
ATOM   7382  C CA  . LEU E 1 199 ? -77.920  32.638  31.406  1.00 52.78  ? 406 LEU E CA  1 
ATOM   7383  C C   . LEU E 1 199 ? -78.843  31.455  31.165  1.00 50.64  ? 406 LEU E C   1 
ATOM   7384  O O   . LEU E 1 199 ? -78.379  30.321  31.044  1.00 55.76  ? 406 LEU E O   1 
ATOM   7385  C CB  . LEU E 1 199 ? -77.137  32.979  30.144  1.00 55.19  ? 406 LEU E CB  1 
ATOM   7386  C CG  . LEU E 1 199 ? -76.151  34.144  30.272  1.00 56.23  ? 406 LEU E CG  1 
ATOM   7387  C CD1 . LEU E 1 199 ? -75.640  34.552  28.894  1.00 59.21  ? 406 LEU E CD1 1 
ATOM   7388  C CD2 . LEU E 1 199 ? -76.757  35.339  31.005  1.00 48.98  ? 406 LEU E CD2 1 
ATOM   7389  N N   . MET E 1 200 ? -80.151  31.703  31.134  1.00 53.14  ? 407 MET E N   1 
ATOM   7390  C CA  . MET E 1 200 ? -81.125  30.603  31.170  1.00 56.03  ? 407 MET E CA  1 
ATOM   7391  C C   . MET E 1 200 ? -81.412  30.084  29.760  1.00 56.73  ? 407 MET E C   1 
ATOM   7392  O O   . MET E 1 200 ? -82.490  30.250  29.192  1.00 54.85  ? 407 MET E O   1 
ATOM   7393  C CB  . MET E 1 200 ? -82.389  31.054  31.871  1.00 55.44  ? 407 MET E CB  1 
ATOM   7394  C CG  . MET E 1 200 ? -82.143  31.279  33.323  1.00 59.86  ? 407 MET E CG  1 
ATOM   7395  S SD  . MET E 1 200 ? -82.631  29.835  34.213  1.00 65.35  ? 407 MET E SD  1 
ATOM   7396  C CE  . MET E 1 200 ? -84.397  30.159  34.276  1.00 53.63  ? 407 MET E CE  1 
ATOM   7397  N N   . ARG E 1 201 ? -80.411  29.415  29.209  1.00 52.75  ? 408 ARG E N   1 
ATOM   7398  C CA  . ARG E 1 201 ? -80.439  29.034  27.806  1.00 54.05  ? 408 ARG E CA  1 
ATOM   7399  C C   . ARG E 1 201 ? -81.125  27.705  27.575  1.00 55.51  ? 408 ARG E C   1 
ATOM   7400  O O   . ARG E 1 201 ? -80.680  26.936  26.724  1.00 55.94  ? 408 ARG E O   1 
ATOM   7401  C CB  . ARG E 1 201 ? -79.018  29.004  27.266  1.00 56.51  ? 408 ARG E CB  1 
ATOM   7402  C CG  . ARG E 1 201 ? -78.455  30.360  26.889  1.00 52.69  ? 408 ARG E CG  1 
ATOM   7403  C CD  . ARG E 1 201 ? -77.275  30.154  25.948  1.00 62.65  ? 408 ARG E CD  1 
ATOM   7404  N NE  . ARG E 1 201 ? -76.670  31.400  25.483  1.00 64.93  ? 408 ARG E NE  1 
ATOM   7405  C CZ  . ARG E 1 201 ? -77.091  32.086  24.425  1.00 58.25  ? 408 ARG E CZ  1 
ATOM   7406  N NH1 . ARG E 1 201 ? -78.123  31.663  23.717  1.00 55.32  ? 408 ARG E NH1 1 
ATOM   7407  N NH2 . ARG E 1 201 ? -76.473  33.198  24.078  1.00 62.79  ? 408 ARG E NH2 1 
ATOM   7408  N N   . PHE E 1 202 ? -82.169  27.417  28.349  1.00 52.98  ? 409 PHE E N   1 
ATOM   7409  C CA  . PHE E 1 202 ? -82.937  26.153  28.205  1.00 56.24  ? 409 PHE E CA  1 
ATOM   7410  C C   . PHE E 1 202 ? -84.409  26.487  27.969  1.00 56.09  ? 409 PHE E C   1 
ATOM   7411  O O   . PHE E 1 202 ? -84.846  27.557  28.413  1.00 52.98  ? 409 PHE E O   1 
ATOM   7412  C CB  . PHE E 1 202 ? -82.736  25.220  29.399  1.00 55.21  ? 409 PHE E CB  1 
ATOM   7413  C CG  . PHE E 1 202 ? -81.926  25.732  30.558  1.00 53.59  ? 409 PHE E CG  1 
ATOM   7414  C CD1 . PHE E 1 202 ? -82.523  26.461  31.571  1.00 53.49  ? 409 PHE E CD1 1 
ATOM   7415  C CD2 . PHE E 1 202 ? -80.581  25.429  30.663  1.00 50.63  ? 409 PHE E CD2 1 
ATOM   7416  C CE1 . PHE E 1 202 ? -81.778  26.905  32.648  1.00 53.53  ? 409 PHE E CE1 1 
ATOM   7417  C CE2 . PHE E 1 202 ? -79.840  25.877  31.741  1.00 49.04  ? 409 PHE E CE2 1 
ATOM   7418  C CZ  . PHE E 1 202 ? -80.439  26.618  32.729  1.00 54.90  ? 409 PHE E CZ  1 
ATOM   7419  N N   . MET E 1 203 ? -85.176  25.565  27.378  1.00 63.35  ? 410 MET E N   1 
ATOM   7420  C CA  . MET E 1 203 ? -86.522  25.950  26.973  1.00 69.77  ? 410 MET E CA  1 
ATOM   7421  C C   . MET E 1 203 ? -87.418  24.724  26.889  1.00 75.42  ? 410 MET E C   1 
ATOM   7422  O O   . MET E 1 203 ? -86.965  23.582  27.022  1.00 71.14  ? 410 MET E O   1 
ATOM   7423  C CB  . MET E 1 203 ? -86.500  26.671  25.616  1.00 71.05  ? 410 MET E CB  1 
ATOM   7424  C CG  . MET E 1 203 ? -87.634  27.663  25.405  1.00 70.18  ? 410 MET E CG  1 
ATOM   7425  S SD  . MET E 1 203 ? -88.052  27.851  23.667  1.00 103.43 ? 410 MET E SD  1 
ATOM   7426  C CE  . MET E 1 203 ? -86.985  29.193  23.174  1.00 69.02  ? 410 MET E CE  1 
ATOM   7427  N N   . TYR E 1 204 ? -88.710  25.002  26.666  1.00 79.07  ? 411 TYR E N   1 
ATOM   7428  C CA  . TYR E 1 204 ? -89.756  24.038  26.291  1.00 79.00  ? 411 TYR E CA  1 
ATOM   7429  C C   . TYR E 1 204 ? -89.917  22.866  27.255  1.00 72.03  ? 411 TYR E C   1 
ATOM   7430  O O   . TYR E 1 204 ? -90.091  21.721  26.823  1.00 76.70  ? 411 TYR E O   1 
ATOM   7431  C CB  . TYR E 1 204 ? -89.499  23.513  24.873  1.00 71.26  ? 411 TYR E CB  1 
ATOM   7432  N N   . GLN E 1 210 ? -90.013  17.842  24.409  1.00 77.72  ? 417 GLN E N   1 
ATOM   7433  C CA  . GLN E 1 210 ? -88.566  17.867  24.645  1.00 77.87  ? 417 GLN E CA  1 
ATOM   7434  C C   . GLN E 1 210 ? -88.086  19.229  25.152  1.00 75.01  ? 417 GLN E C   1 
ATOM   7435  O O   . GLN E 1 210 ? -88.519  20.272  24.670  1.00 71.73  ? 417 GLN E O   1 
ATOM   7436  C CB  . GLN E 1 210 ? -87.801  17.499  23.366  1.00 61.94  ? 417 GLN E CB  1 
ATOM   7437  N N   . ASN E 1 211 ? -87.194  19.227  26.138  1.00 74.66  ? 418 ASN E N   1 
ATOM   7438  C CA  . ASN E 1 211 ? -86.538  20.457  26.562  1.00 71.27  ? 418 ASN E CA  1 
ATOM   7439  C C   . ASN E 1 211 ? -85.241  20.609  25.779  1.00 70.40  ? 418 ASN E C   1 
ATOM   7440  O O   . ASN E 1 211 ? -84.473  19.653  25.624  1.00 63.24  ? 418 ASN E O   1 
ATOM   7441  C CB  . ASN E 1 211 ? -86.285  20.463  28.076  1.00 70.19  ? 418 ASN E CB  1 
ATOM   7442  C CG  . ASN E 1 211 ? -87.592  20.528  28.888  1.00 73.27  ? 418 ASN E CG  1 
ATOM   7443  O OD1 . ASN E 1 211 ? -88.120  21.608  29.162  1.00 69.29  ? 418 ASN E OD1 1 
ATOM   7444  N ND2 . ASN E 1 211 ? -88.117  19.366  29.260  1.00 77.57  ? 418 ASN E ND2 1 
ATOM   7445  N N   . ILE E 1 212 ? -85.048  21.806  25.225  1.00 70.35  ? 419 ILE E N   1 
ATOM   7446  C CA  . ILE E 1 212 ? -83.906  22.033  24.299  1.00 68.26  ? 419 ILE E CA  1 
ATOM   7447  C C   . ILE E 1 212 ? -83.059  23.222  24.758  1.00 65.19  ? 419 ILE E C   1 
ATOM   7448  O O   . ILE E 1 212 ? -83.448  23.876  25.729  1.00 64.33  ? 419 ILE E O   1 
ATOM   7449  C CB  . ILE E 1 212 ? -84.507  22.247  22.894  1.00 65.60  ? 419 ILE E CB  1 
ATOM   7450  C CG1 . ILE E 1 212 ? -83.512  21.951  21.766  1.00 83.01  ? 419 ILE E CG1 1 
ATOM   7451  C CG2 . ILE E 1 212 ? -85.131  23.631  22.760  1.00 64.31  ? 419 ILE E CG2 1 
ATOM   7452  C CD1 . ILE E 1 212 ? -82.815  20.616  21.891  1.00 80.52  ? 419 ILE E CD1 1 
ATOM   7453  N N   . LYS E 1 213 ? -81.928  23.463  24.092  1.00 58.65  ? 420 LYS E N   1 
ATOM   7454  C CA  . LYS E 1 213 ? -81.059  24.623  24.407  1.00 65.10  ? 420 LYS E CA  1 
ATOM   7455  C C   . LYS E 1 213 ? -81.463  25.825  23.557  1.00 62.33  ? 420 LYS E C   1 
ATOM   7456  O O   . LYS E 1 213 ? -81.816  25.630  22.388  1.00 66.78  ? 420 LYS E O   1 
ATOM   7457  C CB  . LYS E 1 213 ? -79.592  24.286  24.133  1.00 62.12  ? 420 LYS E CB  1 
ATOM   7458  C CG  . LYS E 1 213 ? -78.582  25.319  24.608  1.00 58.89  ? 420 LYS E CG  1 
ATOM   7459  C CD  . LYS E 1 213 ? -77.385  25.442  23.708  1.00 64.02  ? 420 LYS E CD  1 
ATOM   7460  C CE  . LYS E 1 213 ? -76.262  26.239  24.328  1.00 60.77  ? 420 LYS E CE  1 
ATOM   7461  N NZ  . LYS E 1 213 ? -74.992  26.058  23.589  1.00 64.21  ? 420 LYS E NZ  1 
ATOM   7462  N N   . ILE E 1 214 ? -81.408  27.020  24.135  1.00 54.50  ? 421 ILE E N   1 
ATOM   7463  C CA  . ILE E 1 214 ? -81.702  28.264  23.379  1.00 54.74  ? 421 ILE E CA  1 
ATOM   7464  C C   . ILE E 1 214 ? -80.388  28.783  22.816  1.00 58.05  ? 421 ILE E C   1 
ATOM   7465  O O   . ILE E 1 214 ? -79.442  28.940  23.591  1.00 63.80  ? 421 ILE E O   1 
ATOM   7466  C CB  . ILE E 1 214 ? -82.332  29.309  24.316  1.00 53.80  ? 421 ILE E CB  1 
ATOM   7467  C CG1 . ILE E 1 214 ? -83.618  28.812  24.974  1.00 59.51  ? 421 ILE E CG1 1 
ATOM   7468  C CG2 . ILE E 1 214 ? -82.554  30.633  23.606  1.00 58.75  ? 421 ILE E CG2 1 
ATOM   7469  C CD1 . ILE E 1 214 ? -84.232  29.822  25.913  1.00 58.07  ? 421 ILE E CD1 1 
ATOM   7470  N N   . ASN E 1 215 ? -80.322  29.021  21.513  1.00 56.82  ? 422 ASN E N   1 
ATOM   7471  C CA  . ASN E 1 215 ? -79.128  29.629  20.960  1.00 58.33  ? 422 ASN E CA  1 
ATOM   7472  C C   . ASN E 1 215 ? -79.359  31.050  20.471  1.00 61.07  ? 422 ASN E C   1 
ATOM   7473  O O   . ASN E 1 215 ? -78.491  31.599  19.782  1.00 64.54  ? 422 ASN E O   1 
ATOM   7474  C CB  . ASN E 1 215 ? -78.558  28.751  19.851  1.00 54.90  ? 422 ASN E CB  1 
ATOM   7475  C CG  . ASN E 1 215 ? -77.927  27.479  20.392  1.00 63.10  ? 422 ASN E CG  1 
ATOM   7476  O OD1 . ASN E 1 215 ? -76.838  27.506  20.954  1.00 62.72  ? 422 ASN E OD1 1 
ATOM   7477  N ND2 . ASN E 1 215 ? -78.611  26.354  20.215  1.00 62.63  ? 422 ASN E ND2 1 
ATOM   7478  N N   . ASP E 1 216 ? -80.473  31.677  20.849  1.00 55.69  ? 423 ASP E N   1 
ATOM   7479  C CA  . ASP E 1 216 ? -80.774  33.021  20.375  1.00 58.09  ? 423 ASP E CA  1 
ATOM   7480  C C   . ASP E 1 216 ? -79.657  33.992  20.745  1.00 67.22  ? 423 ASP E C   1 
ATOM   7481  O O   . ASP E 1 216 ? -78.793  33.702  21.573  1.00 65.37  ? 423 ASP E O   1 
ATOM   7482  C CB  . ASP E 1 216 ? -82.088  33.521  20.956  1.00 61.25  ? 423 ASP E CB  1 
ATOM   7483  C CG  . ASP E 1 216 ? -83.256  32.603  20.644  1.00 69.23  ? 423 ASP E CG  1 
ATOM   7484  O OD1 . ASP E 1 216 ? -83.073  31.584  19.926  1.00 59.16  ? 423 ASP E OD1 1 
ATOM   7485  O OD2 . ASP E 1 216 ? -84.365  32.911  21.128  1.00 79.10  ? 423 ASP E OD2 1 
ATOM   7486  N N   . ARG E 1 217 ? -79.682  35.167  20.120  1.00 69.87  ? 424 ARG E N   1 
ATOM   7487  C CA  . ARG E 1 217 ? -78.660  36.175  20.377  1.00 65.30  ? 424 ARG E CA  1 
ATOM   7488  C C   . ARG E 1 217 ? -78.991  36.929  21.660  1.00 67.00  ? 424 ARG E C   1 
ATOM   7489  O O   . ARG E 1 217 ? -80.064  37.527  21.775  1.00 71.67  ? 424 ARG E O   1 
ATOM   7490  C CB  . ARG E 1 217 ? -78.544  37.138  19.196  1.00 63.00  ? 424 ARG E CB  1 
ATOM   7491  N N   . PHE E 1 218 ? -78.069  36.905  22.621  1.00 67.38  ? 425 PHE E N   1 
ATOM   7492  C CA  . PHE E 1 218 ? -78.229  37.594  23.903  1.00 72.73  ? 425 PHE E CA  1 
ATOM   7493  C C   . PHE E 1 218 ? -76.989  38.460  24.146  1.00 71.47  ? 425 PHE E C   1 
ATOM   7494  O O   . PHE E 1 218 ? -75.869  37.944  24.256  1.00 67.39  ? 425 PHE E O   1 
ATOM   7495  C CB  . PHE E 1 218 ? -78.466  36.581  25.038  1.00 67.90  ? 425 PHE E CB  1 
ATOM   7496  C CG  . PHE E 1 218 ? -78.745  37.204  26.384  1.00 59.41  ? 425 PHE E CG  1 
ATOM   7497  C CD1 . PHE E 1 218 ? -80.000  37.714  26.686  1.00 64.85  ? 425 PHE E CD1 1 
ATOM   7498  C CD2 . PHE E 1 218 ? -77.760  37.252  27.356  1.00 58.73  ? 425 PHE E CD2 1 
ATOM   7499  C CE1 . PHE E 1 218 ? -80.262  38.289  27.936  1.00 61.34  ? 425 PHE E CE1 1 
ATOM   7500  C CE2 . PHE E 1 218 ? -78.013  37.826  28.607  1.00 63.66  ? 425 PHE E CE2 1 
ATOM   7501  C CZ  . PHE E 1 218 ? -79.265  38.348  28.892  1.00 57.30  ? 425 PHE E CZ  1 
ATOM   7502  N N   . GLU E 1 219 ? -77.192  39.774  24.221  1.00 64.67  ? 426 GLU E N   1 
ATOM   7503  C CA  . GLU E 1 219 ? -76.103  40.740  24.267  1.00 65.15  ? 426 GLU E CA  1 
ATOM   7504  C C   . GLU E 1 219 ? -75.730  41.047  25.702  1.00 66.76  ? 426 GLU E C   1 
ATOM   7505  O O   . GLU E 1 219 ? -76.603  41.183  26.558  1.00 68.47  ? 426 GLU E O   1 
ATOM   7506  C CB  . GLU E 1 219 ? -76.505  42.027  23.539  1.00 74.68  ? 426 GLU E CB  1 
ATOM   7507  N N   . PHE E 1 220 ? -74.433  41.158  25.964  1.00 60.95  ? 427 PHE E N   1 
ATOM   7508  C CA  . PHE E 1 220 ? -74.011  41.543  27.305  1.00 61.38  ? 427 PHE E CA  1 
ATOM   7509  C C   . PHE E 1 220 ? -72.847  42.519  27.204  1.00 65.51  ? 427 PHE E C   1 
ATOM   7510  O O   . PHE E 1 220 ? -71.902  42.274  26.443  1.00 61.59  ? 427 PHE E O   1 
ATOM   7511  C CB  . PHE E 1 220 ? -73.621  40.332  28.163  1.00 57.10  ? 427 PHE E CB  1 
ATOM   7512  C CG  . PHE E 1 220 ? -72.656  39.377  27.501  1.00 63.62  ? 427 PHE E CG  1 
ATOM   7513  C CD1 . PHE E 1 220 ? -73.110  38.374  26.660  1.00 60.63  ? 427 PHE E CD1 1 
ATOM   7514  C CD2 . PHE E 1 220 ? -71.293  39.452  27.762  1.00 64.72  ? 427 PHE E CD2 1 
ATOM   7515  C CE1 . PHE E 1 220 ? -72.225  37.488  26.077  1.00 57.28  ? 427 PHE E CE1 1 
ATOM   7516  C CE2 . PHE E 1 220 ? -70.401  38.558  27.178  1.00 61.51  ? 427 PHE E CE2 1 
ATOM   7517  C CZ  . PHE E 1 220 ? -70.870  37.582  26.334  1.00 58.38  ? 427 PHE E CZ  1 
ATOM   7518  N N   . PRO E 1 221 ? -72.890  43.616  27.960  1.00 64.24  ? 428 PRO E N   1 
ATOM   7519  C CA  . PRO E 1 221 ? -71.884  44.669  27.820  1.00 58.58  ? 428 PRO E CA  1 
ATOM   7520  C C   . PRO E 1 221 ? -70.608  44.387  28.594  1.00 63.18  ? 428 PRO E C   1 
ATOM   7521  O O   . PRO E 1 221 ? -70.551  43.555  29.498  1.00 65.73  ? 428 PRO E O   1 
ATOM   7522  C CB  . PRO E 1 221 ? -72.589  45.903  28.395  1.00 65.16  ? 428 PRO E CB  1 
ATOM   7523  C CG  . PRO E 1 221 ? -73.459  45.358  29.447  1.00 68.12  ? 428 PRO E CG  1 
ATOM   7524  C CD  . PRO E 1 221 ? -73.928  43.993  28.930  1.00 67.75  ? 428 PRO E CD  1 
ATOM   7525  N N   . GLU E 1 222 ? -69.566  45.127  28.213  1.00 73.29  ? 429 GLU E N   1 
ATOM   7526  C CA  . GLU E 1 222 ? -68.311  45.074  28.952  1.00 72.69  ? 429 GLU E CA  1 
ATOM   7527  C C   . GLU E 1 222 ? -68.453  45.777  30.294  1.00 68.21  ? 429 GLU E C   1 
ATOM   7528  O O   . GLU E 1 222 ? -67.903  45.324  31.305  1.00 67.06  ? 429 GLU E O   1 
ATOM   7529  C CB  . GLU E 1 222 ? -67.193  45.705  28.120  1.00 69.52  ? 429 GLU E CB  1 
ATOM   7530  C CG  . GLU E 1 222 ? -65.991  44.817  27.982  1.00 74.26  ? 429 GLU E CG  1 
ATOM   7531  C CD  . GLU E 1 222 ? -64.753  45.575  27.563  1.00 86.13  ? 429 GLU E CD  1 
ATOM   7532  O OE1 . GLU E 1 222 ? -64.904  46.661  26.955  1.00 88.33  ? 429 GLU E OE1 1 
ATOM   7533  O OE2 . GLU E 1 222 ? -63.634  45.085  27.866  1.00 78.60  ? 429 GLU E OE2 1 
ATOM   7534  N N   . GLN E 1 223 ? -69.188  46.885  30.312  1.00 68.05  ? 430 GLN E N   1 
ATOM   7535  C CA  . GLN E 1 223 ? -69.513  47.633  31.515  1.00 66.52  ? 430 GLN E CA  1 
ATOM   7536  C C   . GLN E 1 223 ? -71.008  47.496  31.769  1.00 70.37  ? 430 GLN E C   1 
ATOM   7537  O O   . GLN E 1 223 ? -71.822  47.738  30.868  1.00 73.15  ? 430 GLN E O   1 
ATOM   7538  C CB  . GLN E 1 223 ? -69.124  49.110  31.361  1.00 68.76  ? 430 GLN E CB  1 
ATOM   7539  C CG  . GLN E 1 223 ? -68.368  49.704  32.538  1.00 72.19  ? 430 GLN E CG  1 
ATOM   7540  C CD  . GLN E 1 223 ? -69.301  50.324  33.579  1.00 81.32  ? 430 GLN E CD  1 
ATOM   7541  O OE1 . GLN E 1 223 ? -70.251  51.039  33.238  1.00 84.63  ? 430 GLN E OE1 1 
ATOM   7542  N NE2 . GLN E 1 223 ? -69.043  50.035  34.854  1.00 72.56  ? 430 GLN E NE2 1 
ATOM   7543  N N   . LEU E 1 224 ? -71.374  47.125  32.997  1.00 66.40  ? 431 LEU E N   1 
ATOM   7544  C CA  . LEU E 1 224 ? -72.802  46.901  33.331  1.00 68.71  ? 431 LEU E CA  1 
ATOM   7545  C C   . LEU E 1 224 ? -73.189  47.677  34.586  1.00 70.47  ? 431 LEU E C   1 
ATOM   7546  O O   . LEU E 1 224 ? -72.744  47.307  35.674  1.00 67.60  ? 431 LEU E O   1 
ATOM   7547  C CB  . LEU E 1 224 ? -73.014  45.398  33.530  1.00 68.35  ? 431 LEU E CB  1 
ATOM   7548  C CG  . LEU E 1 224 ? -74.406  44.955  33.968  1.00 64.97  ? 431 LEU E CG  1 
ATOM   7549  C CD1 . LEU E 1 224 ? -75.467  45.453  33.004  1.00 70.46  ? 431 LEU E CD1 1 
ATOM   7550  C CD2 . LEU E 1 224 ? -74.470  43.445  34.097  1.00 64.24  ? 431 LEU E CD2 1 
ATOM   7551  N N   . PRO E 1 225 ? -73.944  48.807  34.493  1.00 71.65  ? 432 PRO E N   1 
ATOM   7552  C CA  . PRO E 1 225 ? -74.451  49.462  35.690  1.00 69.53  ? 432 PRO E CA  1 
ATOM   7553  C C   . PRO E 1 225 ? -75.797  48.862  36.102  1.00 64.56  ? 432 PRO E C   1 
ATOM   7554  O O   . PRO E 1 225 ? -76.672  48.709  35.281  1.00 62.90  ? 432 PRO E O   1 
ATOM   7555  C CB  . PRO E 1 225 ? -74.612  50.940  35.326  1.00 77.74  ? 432 PRO E CB  1 
ATOM   7556  C CG  . PRO E 1 225 ? -74.842  50.954  33.838  1.00 80.75  ? 432 PRO E CG  1 
ATOM   7557  C CD  . PRO E 1 225 ? -74.225  49.676  33.314  1.00 70.53  ? 432 PRO E CD  1 
ATOM   7558  N N   . LEU E 1 226 ? -75.924  48.545  37.379  1.00 61.91  ? 433 LEU E N   1 
ATOM   7559  C CA  . LEU E 1 226 ? -77.158  47.904  37.898  1.00 60.96  ? 433 LEU E CA  1 
ATOM   7560  C C   . LEU E 1 226 ? -77.786  48.744  39.014  1.00 62.45  ? 433 LEU E C   1 
ATOM   7561  O O   . LEU E 1 226 ? -78.689  48.225  39.676  1.00 61.10  ? 433 LEU E O   1 
ATOM   7562  C CB  . LEU E 1 226 ? -76.796  46.506  38.399  1.00 55.81  ? 433 LEU E CB  1 
ATOM   7563  C CG  . LEU E 1 226 ? -76.271  45.545  37.342  1.00 56.03  ? 433 LEU E CG  1 
ATOM   7564  C CD1 . LEU E 1 226 ? -75.700  44.305  37.992  1.00 51.54  ? 433 LEU E CD1 1 
ATOM   7565  C CD2 . LEU E 1 226 ? -77.371  45.173  36.370  1.00 55.72  ? 433 LEU E CD2 1 
ATOM   7566  N N   . ASP E 1 227 ? -77.322  49.978  39.221  1.00 62.74  ? 434 ASP E N   1 
ATOM   7567  C CA  . ASP E 1 227 ? -77.948  50.856  40.203  1.00 60.93  ? 434 ASP E CA  1 
ATOM   7568  C C   . ASP E 1 227 ? -79.456  50.914  40.009  1.00 64.71  ? 434 ASP E C   1 
ATOM   7569  O O   . ASP E 1 227 ? -80.201  51.175  40.964  1.00 59.33  ? 434 ASP E O   1 
ATOM   7570  C CB  . ASP E 1 227 ? -77.349  52.254  40.091  1.00 55.03  ? 434 ASP E CB  1 
ATOM   7571  C CG  . ASP E 1 227 ? -76.451  52.610  41.251  1.00 61.72  ? 434 ASP E CG  1 
ATOM   7572  O OD1 . ASP E 1 227 ? -76.147  51.745  42.100  1.00 61.59  ? 434 ASP E OD1 1 
ATOM   7573  O OD2 . ASP E 1 227 ? -76.044  53.787  41.314  1.00 72.08  ? 434 ASP E OD2 1 
ATOM   7574  N N   . GLU E 1 228 ? -79.920  50.654  38.778  1.00 60.82  ? 435 GLU E N   1 
ATOM   7575  C CA  . GLU E 1 228 ? -81.345  50.713  38.492  1.00 61.02  ? 435 GLU E CA  1 
ATOM   7576  C C   . GLU E 1 228 ? -82.114  49.625  39.230  1.00 66.37  ? 435 GLU E C   1 
ATOM   7577  O O   . GLU E 1 228 ? -83.255  49.843  39.660  1.00 66.59  ? 435 GLU E O   1 
ATOM   7578  C CB  . GLU E 1 228 ? -81.591  50.610  36.989  1.00 55.31  ? 435 GLU E CB  1 
ATOM   7579  C CG  . GLU E 1 228 ? -83.028  51.003  36.609  1.00 65.68  ? 435 GLU E CG  1 
ATOM   7580  C CD  . GLU E 1 228 ? -83.515  50.329  35.333  1.00 79.00  ? 435 GLU E CD  1 
ATOM   7581  O OE1 . GLU E 1 228 ? -84.745  50.107  35.188  1.00 84.34  ? 435 GLU E OE1 1 
ATOM   7582  O OE2 . GLU E 1 228 ? -82.662  50.026  34.469  1.00 80.42  ? 435 GLU E OE2 1 
ATOM   7583  N N   . PHE E 1 229 ? -81.508  48.458  39.411  1.00 66.67  ? 436 PHE E N   1 
ATOM   7584  C CA  . PHE E 1 229 ? -82.224  47.336  39.993  1.00 63.68  ? 436 PHE E CA  1 
ATOM   7585  C C   . PHE E 1 229 ? -81.981  47.196  41.494  1.00 61.58  ? 436 PHE E C   1 
ATOM   7586  O O   . PHE E 1 229 ? -82.291  46.156  42.084  1.00 65.05  ? 436 PHE E O   1 
ATOM   7587  C CB  . PHE E 1 229 ? -81.865  46.085  39.212  1.00 55.10  ? 436 PHE E CB  1 
ATOM   7588  C CG  . PHE E 1 229 ? -81.860  46.320  37.734  1.00 60.87  ? 436 PHE E CG  1 
ATOM   7589  C CD1 . PHE E 1 229 ? -83.048  46.377  37.031  1.00 57.04  ? 436 PHE E CD1 1 
ATOM   7590  C CD2 . PHE E 1 229 ? -80.670  46.538  37.048  1.00 60.91  ? 436 PHE E CD2 1 
ATOM   7591  C CE1 . PHE E 1 229 ? -83.044  46.613  35.658  1.00 55.53  ? 436 PHE E CE1 1 
ATOM   7592  C CE2 . PHE E 1 229 ? -80.671  46.765  35.674  1.00 57.84  ? 436 PHE E CE2 1 
ATOM   7593  C CZ  . PHE E 1 229 ? -81.859  46.804  34.987  1.00 47.42  ? 436 PHE E CZ  1 
ATOM   7594  N N   . LEU E 1 230 ? -81.467  48.236  42.130  1.00 58.20  ? 437 LEU E N   1 
ATOM   7595  C CA  . LEU E 1 230 ? -81.420  48.276  43.575  1.00 57.44  ? 437 LEU E CA  1 
ATOM   7596  C C   . LEU E 1 230 ? -82.647  49.004  44.095  1.00 62.12  ? 437 LEU E C   1 
ATOM   7597  O O   . LEU E 1 230 ? -83.208  49.869  43.418  1.00 66.69  ? 437 LEU E O   1 
ATOM   7598  C CB  . LEU E 1 230 ? -80.155  48.975  44.060  1.00 56.98  ? 437 LEU E CB  1 
ATOM   7599  C CG  . LEU E 1 230 ? -78.849  48.230  43.812  1.00 61.28  ? 437 LEU E CG  1 
ATOM   7600  C CD1 . LEU E 1 230 ? -77.717  49.217  43.891  1.00 62.12  ? 437 LEU E CD1 1 
ATOM   7601  C CD2 . LEU E 1 230 ? -78.638  47.057  44.805  1.00 59.32  ? 437 LEU E CD2 1 
ATOM   7602  N N   . GLN E 1 231 ? -83.078  48.617  45.296  1.00 56.25  ? 438 GLN E N   1 
ATOM   7603  C CA  . GLN E 1 231 ? -84.096  49.369  46.005  1.00 55.71  ? 438 GLN E CA  1 
ATOM   7604  C C   . GLN E 1 231 ? -83.556  50.706  46.504  1.00 72.07  ? 438 GLN E C   1 
ATOM   7605  O O   . GLN E 1 231 ? -84.346  51.633  46.735  1.00 70.80  ? 438 GLN E O   1 
ATOM   7606  C CB  . GLN E 1 231 ? -84.632  48.532  47.171  1.00 55.92  ? 438 GLN E CB  1 
ATOM   7607  C CG  . GLN E 1 231 ? -86.009  48.931  47.688  1.00 61.80  ? 438 GLN E CG  1 
ATOM   7608  C CD  . GLN E 1 231 ? -87.135  48.638  46.698  1.00 67.69  ? 438 GLN E CD  1 
ATOM   7609  O OE1 . GLN E 1 231 ? -87.159  47.592  46.055  1.00 68.29  ? 438 GLN E OE1 1 
ATOM   7610  N NE2 . GLN E 1 231 ? -88.083  49.564  46.588  1.00 70.78  ? 438 GLN E NE2 1 
ATOM   7611  N N   . LYS E 1 232 ? -82.242  50.784  46.697  1.00 74.61  ? 439 LYS E N   1 
ATOM   7612  C CA  . LYS E 1 232 ? -81.618  52.037  47.181  1.00 71.35  ? 439 LYS E CA  1 
ATOM   7613  C C   . LYS E 1 232 ? -80.203  52.151  46.633  1.00 68.42  ? 439 LYS E C   1 
ATOM   7614  O O   . LYS E 1 232 ? -79.355  51.336  47.021  1.00 72.72  ? 439 LYS E O   1 
ATOM   7615  C CB  . LYS E 1 232 ? -81.591  52.073  48.709  1.00 69.45  ? 439 LYS E CB  1 
ATOM   7616  C CG  . LYS E 1 232 ? -81.656  53.461  49.328  1.00 70.82  ? 439 LYS E CG  1 
ATOM   7617  C CD  . LYS E 1 232 ? -80.852  53.568  50.601  1.00 76.04  ? 439 LYS E CD  1 
ATOM   7618  C CE  . LYS E 1 232 ? -80.863  54.962  51.189  1.00 79.32  ? 439 LYS E CE  1 
ATOM   7619  N NZ  . LYS E 1 232 ? -82.038  55.174  52.066  1.00 73.37  ? 439 LYS E NZ  1 
ATOM   7620  N N   . THR E 1 233 ? -79.966  53.128  45.761  1.00 70.12  ? 440 THR E N   1 
ATOM   7621  C CA  . THR E 1 233 ? -78.623  53.388  45.271  1.00 65.11  ? 440 THR E CA  1 
ATOM   7622  C C   . THR E 1 233 ? -77.745  53.926  46.393  1.00 69.89  ? 440 THR E C   1 
ATOM   7623  O O   . THR E 1 233 ? -78.225  54.304  47.466  1.00 71.61  ? 440 THR E O   1 
ATOM   7624  C CB  . THR E 1 233 ? -78.639  54.411  44.148  1.00 67.31  ? 440 THR E CB  1 
ATOM   7625  O OG1 . THR E 1 233 ? -78.869  55.707  44.710  1.00 70.11  ? 440 THR E OG1 1 
ATOM   7626  C CG2 . THR E 1 233 ? -79.726  54.091  43.165  1.00 74.47  ? 440 THR E CG2 1 
ATOM   7627  N N   . ASP E 1 234 ? -76.440  53.958  46.121  1.00 73.92  ? 441 ASP E N   1 
ATOM   7628  C CA  . ASP E 1 234 ? -75.448  54.632  46.963  1.00 74.90  ? 441 ASP E CA  1 
ATOM   7629  C C   . ASP E 1 234 ? -74.657  55.595  46.087  1.00 73.84  ? 441 ASP E C   1 
ATOM   7630  O O   . ASP E 1 234 ? -73.991  55.154  45.122  1.00 68.33  ? 441 ASP E O   1 
ATOM   7631  C CB  . ASP E 1 234 ? -74.512  53.629  47.648  1.00 73.57  ? 441 ASP E CB  1 
ATOM   7632  C CG  . ASP E 1 234 ? -73.484  54.294  48.542  1.00 72.14  ? 441 ASP E CG  1 
ATOM   7633  O OD1 . ASP E 1 234 ? -73.494  55.535  48.679  1.00 73.09  ? 441 ASP E OD1 1 
ATOM   7634  O OD2 . ASP E 1 234 ? -72.656  53.563  49.112  1.00 72.94  ? 441 ASP E OD2 1 
ATOM   7635  N N   . PRO E 1 235 ? -74.696  56.901  46.362  1.00 78.52  ? 442 PRO E N   1 
ATOM   7636  C CA  . PRO E 1 235 ? -73.880  57.829  45.565  1.00 78.66  ? 442 PRO E CA  1 
ATOM   7637  C C   . PRO E 1 235 ? -72.390  57.639  45.786  1.00 75.97  ? 442 PRO E C   1 
ATOM   7638  O O   . PRO E 1 235 ? -71.605  57.849  44.851  1.00 74.32  ? 442 PRO E O   1 
ATOM   7639  C CB  . PRO E 1 235 ? -74.365  59.207  46.036  1.00 70.20  ? 442 PRO E CB  1 
ATOM   7640  C CG  . PRO E 1 235 ? -75.719  58.945  46.613  1.00 68.76  ? 442 PRO E CG  1 
ATOM   7641  C CD  . PRO E 1 235 ? -75.593  57.619  47.278  1.00 69.78  ? 442 PRO E CD  1 
ATOM   7642  N N   . LYS E 1 236 ? -71.990  57.222  46.993  1.00 71.89  ? 443 LYS E N   1 
ATOM   7643  C CA  . LYS E 1 236 ? -70.593  56.932  47.293  1.00 75.67  ? 443 LYS E CA  1 
ATOM   7644  C C   . LYS E 1 236 ? -70.088  55.642  46.633  1.00 80.80  ? 443 LYS E C   1 
ATOM   7645  O O   . LYS E 1 236 ? -68.866  55.460  46.530  1.00 82.06  ? 443 LYS E O   1 
ATOM   7646  C CB  . LYS E 1 236 ? -70.398  56.854  48.813  1.00 74.03  ? 443 LYS E CB  1 
ATOM   7647  N N   . ASP E 1 237 ? -71.002  54.738  46.259  1.00 74.86  ? 444 ASP E N   1 
ATOM   7648  C CA  . ASP E 1 237 ? -70.625  53.450  45.613  1.00 68.71  ? 444 ASP E CA  1 
ATOM   7649  C C   . ASP E 1 237 ? -71.665  53.068  44.563  1.00 72.86  ? 444 ASP E C   1 
ATOM   7650  O O   . ASP E 1 237 ? -72.632  52.373  44.909  1.00 67.82  ? 444 ASP E O   1 
ATOM   7651  C CB  . ASP E 1 237 ? -70.466  52.307  46.615  1.00 65.89  ? 444 ASP E CB  1 
ATOM   7652  C CG  . ASP E 1 237 ? -69.745  51.080  46.080  1.00 68.71  ? 444 ASP E CG  1 
ATOM   7653  O OD1 . ASP E 1 237 ? -69.575  50.975  44.854  1.00 63.18  ? 444 ASP E OD1 1 
ATOM   7654  O OD2 . ASP E 1 237 ? -69.361  50.232  46.901  1.00 64.51  ? 444 ASP E OD2 1 
ATOM   7655  N N   . PRO E 1 238 ? -71.494  53.478  43.294  1.00 73.29  ? 445 PRO E N   1 
ATOM   7656  C CA  . PRO E 1 238 ? -72.397  53.058  42.232  1.00 69.57  ? 445 PRO E CA  1 
ATOM   7657  C C   . PRO E 1 238 ? -72.292  51.555  41.933  1.00 74.46  ? 445 PRO E C   1 
ATOM   7658  O O   . PRO E 1 238 ? -71.193  51.043  41.938  1.00 70.52  ? 445 PRO E O   1 
ATOM   7659  C CB  . PRO E 1 238 ? -71.869  53.856  41.037  1.00 64.96  ? 445 PRO E CB  1 
ATOM   7660  C CG  . PRO E 1 238 ? -71.150  55.024  41.650  1.00 69.92  ? 445 PRO E CG  1 
ATOM   7661  C CD  . PRO E 1 238 ? -70.462  54.405  42.841  1.00 71.93  ? 445 PRO E CD  1 
ATOM   7662  N N   . ALA E 1 239 ? -73.427  50.896  41.679  1.00 66.53  ? 446 ALA E N   1 
ATOM   7663  C CA  . ALA E 1 239 ? -73.438  49.451  41.357  1.00 58.13  ? 446 ALA E CA  1 
ATOM   7664  C C   . ALA E 1 239 ? -73.029  49.267  39.904  1.00 67.12  ? 446 ALA E C   1 
ATOM   7665  O O   . ALA E 1 239 ? -73.825  48.752  39.116  1.00 65.58  ? 446 ALA E O   1 
ATOM   7666  C CB  . ALA E 1 239 ? -74.779  48.848  41.641  1.00 54.37  ? 446 ALA E CB  1 
ATOM   7667  N N   . ASN E 1 240 ? -71.821  49.692  39.579  1.00 67.40  ? 447 ASN E N   1 
ATOM   7668  C CA  . ASN E 1 240 ? -71.269  49.541  38.239  1.00 68.34  ? 447 ASN E CA  1 
ATOM   7669  C C   . ASN E 1 240 ? -70.316  48.349  38.238  1.00 65.85  ? 447 ASN E C   1 
ATOM   7670  O O   . ASN E 1 240 ? -69.424  48.254  39.092  1.00 61.07  ? 447 ASN E O   1 
ATOM   7671  C CB  . ASN E 1 240 ? -70.569  50.824  37.769  1.00 67.07  ? 447 ASN E CB  1 
ATOM   7672  N N   . TYR E 1 241 ? -70.555  47.466  37.267  1.00 68.69  ? 448 TYR E N   1 
ATOM   7673  C CA  . TYR E 1 241 ? -69.811  46.192  37.203  1.00 61.41  ? 448 TYR E CA  1 
ATOM   7674  C C   . TYR E 1 241 ? -69.009  46.084  35.917  1.00 63.66  ? 448 TYR E C   1 
ATOM   7675  O O   . TYR E 1 241 ? -69.392  46.672  34.908  1.00 67.66  ? 448 TYR E O   1 
ATOM   7676  C CB  . TYR E 1 241 ? -70.797  45.034  37.331  1.00 59.78  ? 448 TYR E CB  1 
ATOM   7677  C CG  . TYR E 1 241 ? -71.199  44.771  38.754  1.00 62.83  ? 448 TYR E CG  1 
ATOM   7678  C CD1 . TYR E 1 241 ? -72.111  45.586  39.396  1.00 57.44  ? 448 TYR E CD1 1 
ATOM   7679  C CD2 . TYR E 1 241 ? -70.631  43.733  39.464  1.00 61.28  ? 448 TYR E CD2 1 
ATOM   7680  C CE1 . TYR E 1 241 ? -72.461  45.373  40.714  1.00 54.82  ? 448 TYR E CE1 1 
ATOM   7681  C CE2 . TYR E 1 241 ? -70.967  43.503  40.782  1.00 52.08  ? 448 TYR E CE2 1 
ATOM   7682  C CZ  . TYR E 1 241 ? -71.886  44.324  41.402  1.00 53.03  ? 448 TYR E CZ  1 
ATOM   7683  O OH  . TYR E 1 241 ? -72.216  44.115  42.698  1.00 56.29  ? 448 TYR E OH  1 
ATOM   7684  N N   . ILE E 1 242 ? -67.940  45.305  35.964  1.00 60.46  ? 449 ILE E N   1 
ATOM   7685  C CA  . ILE E 1 242 ? -67.009  45.156  34.843  1.00 62.87  ? 449 ILE E CA  1 
ATOM   7686  C C   . ILE E 1 242 ? -66.833  43.671  34.525  1.00 62.32  ? 449 ILE E C   1 
ATOM   7687  O O   . ILE E 1 242 ? -66.460  42.885  35.406  1.00 61.35  ? 449 ILE E O   1 
ATOM   7688  C CB  . ILE E 1 242 ? -65.660  45.808  35.179  1.00 64.76  ? 449 ILE E CB  1 
ATOM   7689  C CG1 . ILE E 1 242 ? -65.880  47.303  35.371  1.00 60.42  ? 449 ILE E CG1 1 
ATOM   7690  C CG2 . ILE E 1 242 ? -64.581  45.475  34.125  1.00 60.98  ? 449 ILE E CG2 1 
ATOM   7691  C CD1 . ILE E 1 242 ? -64.628  48.087  35.561  1.00 61.41  ? 449 ILE E CD1 1 
ATOM   7692  N N   . LEU E 1 243 ? -67.056  43.291  33.265  1.00 57.06  ? 450 LEU E N   1 
ATOM   7693  C CA  . LEU E 1 243 ? -66.997  41.875  32.906  1.00 61.17  ? 450 LEU E CA  1 
ATOM   7694  C C   . LEU E 1 243 ? -65.604  41.285  33.135  1.00 67.88  ? 450 LEU E C   1 
ATOM   7695  O O   . LEU E 1 243 ? -64.581  41.945  32.922  1.00 68.29  ? 450 LEU E O   1 
ATOM   7696  C CB  . LEU E 1 243 ? -67.425  41.673  31.452  1.00 65.78  ? 450 LEU E CB  1 
ATOM   7697  C CG  . LEU E 1 243 ? -67.026  40.374  30.746  1.00 59.99  ? 450 LEU E CG  1 
ATOM   7698  C CD1 . LEU E 1 243 ? -67.910  39.236  31.173  1.00 65.74  ? 450 LEU E CD1 1 
ATOM   7699  C CD2 . LEU E 1 243 ? -67.137  40.552  29.257  1.00 71.03  ? 450 LEU E CD2 1 
ATOM   7700  N N   . HIS E 1 244 ? -65.567  40.041  33.628  1.00 65.77  ? 451 HIS E N   1 
ATOM   7701  C CA  . HIS E 1 244 ? -64.284  39.361  33.940  1.00 61.21  ? 451 HIS E CA  1 
ATOM   7702  C C   . HIS E 1 244 ? -64.205  38.005  33.249  1.00 60.69  ? 451 HIS E C   1 
ATOM   7703  O O   . HIS E 1 244 ? -63.101  37.645  32.835  1.00 66.83  ? 451 HIS E O   1 
ATOM   7704  C CB  . HIS E 1 244 ? -64.184  39.153  35.448  1.00 61.67  ? 451 HIS E CB  1 
ATOM   7705  C CG  . HIS E 1 244 ? -62.850  38.729  35.957  1.00 62.19  ? 451 HIS E CG  1 
ATOM   7706  N ND1 . HIS E 1 244 ? -62.677  37.565  36.674  1.00 59.97  ? 451 HIS E ND1 1 
ATOM   7707  C CD2 . HIS E 1 244 ? -61.640  39.321  35.902  1.00 65.66  ? 451 HIS E CD2 1 
ATOM   7708  C CE1 . HIS E 1 244 ? -61.414  37.449  37.021  1.00 63.99  ? 451 HIS E CE1 1 
ATOM   7709  N NE2 . HIS E 1 244 ? -60.757  38.509  36.555  1.00 66.48  ? 451 HIS E NE2 1 
ATOM   7710  N N   . ALA E 1 245 ? -65.331  37.307  33.096  1.00 59.72  ? 452 ALA E N   1 
ATOM   7711  C CA  . ALA E 1 245 ? -65.269  35.927  32.573  1.00 53.44  ? 452 ALA E CA  1 
ATOM   7712  C C   . ALA E 1 245 ? -66.524  35.547  31.800  1.00 53.22  ? 452 ALA E C   1 
ATOM   7713  O O   . ALA E 1 245 ? -67.619  35.940  32.209  1.00 53.73  ? 452 ALA E O   1 
ATOM   7714  C CB  . ALA E 1 245 ? -65.066  34.973  33.712  1.00 61.34  ? 452 ALA E CB  1 
ATOM   7715  N N   . VAL E 1 246 ? -66.347  34.780  30.728  1.00 56.36  ? 453 VAL E N   1 
ATOM   7716  C CA  . VAL E 1 246 ? -67.457  34.305  29.916  1.00 53.66  ? 453 VAL E CA  1 
ATOM   7717  C C   . VAL E 1 246 ? -67.306  32.811  29.699  1.00 56.02  ? 453 VAL E C   1 
ATOM   7718  O O   . VAL E 1 246 ? -66.579  32.372  28.801  1.00 58.47  ? 453 VAL E O   1 
ATOM   7719  C CB  . VAL E 1 246 ? -67.523  35.033  28.573  1.00 57.74  ? 453 VAL E CB  1 
ATOM   7720  C CG1 . VAL E 1 246 ? -68.675  34.485  27.741  1.00 54.34  ? 453 VAL E CG1 1 
ATOM   7721  C CG2 . VAL E 1 246 ? -67.655  36.551  28.787  1.00 64.68  ? 453 VAL E CG2 1 
ATOM   7722  N N   . LEU E 1 247 ? -68.000  32.046  30.536  1.00 55.02  ? 454 LEU E N   1 
ATOM   7723  C CA  . LEU E 1 247 ? -67.990  30.572  30.405  1.00 57.34  ? 454 LEU E CA  1 
ATOM   7724  C C   . LEU E 1 247 ? -68.873  30.242  29.207  1.00 58.79  ? 454 LEU E C   1 
ATOM   7725  O O   . LEU E 1 247 ? -70.047  30.636  29.215  1.00 54.07  ? 454 LEU E O   1 
ATOM   7726  C CB  . LEU E 1 247 ? -68.456  29.976  31.733  1.00 54.96  ? 454 LEU E CB  1 
ATOM   7727  C CG  . LEU E 1 247 ? -67.514  30.240  32.909  1.00 54.81  ? 454 LEU E CG  1 
ATOM   7728  C CD1 . LEU E 1 247 ? -67.973  31.418  33.754  1.00 53.68  ? 454 LEU E CD1 1 
ATOM   7729  C CD2 . LEU E 1 247 ? -67.343  29.006  33.773  1.00 46.19  ? 454 LEU E CD2 1 
ATOM   7730  N N   . VAL E 1 248 ? -68.294  29.583  28.209  1.00 55.11  ? 455 VAL E N   1 
ATOM   7731  C CA  . VAL E 1 248 ? -69.005  29.346  26.927  1.00 60.23  ? 455 VAL E CA  1 
ATOM   7732  C C   . VAL E 1 248 ? -69.258  27.861  26.713  1.00 59.08  ? 455 VAL E C   1 
ATOM   7733  O O   . VAL E 1 248 ? -68.323  27.077  26.836  1.00 57.54  ? 455 VAL E O   1 
ATOM   7734  C CB  . VAL E 1 248 ? -68.200  29.967  25.773  1.00 60.83  ? 455 VAL E CB  1 
ATOM   7735  C CG1 . VAL E 1 248 ? -68.681  29.523  24.407  1.00 60.30  ? 455 VAL E CG1 1 
ATOM   7736  C CG2 . VAL E 1 248 ? -68.193  31.475  25.863  1.00 50.21  ? 455 VAL E CG2 1 
ATOM   7737  N N   . HIS E 1 249 ? -70.519  27.524  26.395  1.00 63.22  ? 456 HIS E N   1 
ATOM   7738  C CA  . HIS E 1 249 ? -70.943  26.125  26.120  1.00 61.98  ? 456 HIS E CA  1 
ATOM   7739  C C   . HIS E 1 249 ? -71.114  25.897  24.619  1.00 61.49  ? 456 HIS E C   1 
ATOM   7740  O O   . HIS E 1 249 ? -71.636  26.786  23.940  1.00 63.13  ? 456 HIS E O   1 
ATOM   7741  C CB  . HIS E 1 249 ? -72.232  25.780  26.874  1.00 57.22  ? 456 HIS E CB  1 
ATOM   7742  C CG  . HIS E 1 249 ? -72.716  24.394  26.628  1.00 60.33  ? 456 HIS E CG  1 
ATOM   7743  N ND1 . HIS E 1 249 ? -73.863  24.134  25.915  1.00 60.12  ? 456 HIS E ND1 1 
ATOM   7744  C CD2 . HIS E 1 249 ? -72.201  23.197  26.967  1.00 60.81  ? 456 HIS E CD2 1 
ATOM   7745  C CE1 . HIS E 1 249 ? -74.042  22.836  25.833  1.00 64.02  ? 456 HIS E CE1 1 
ATOM   7746  N NE2 . HIS E 1 249 ? -73.038  22.245  26.466  1.00 62.04  ? 456 HIS E NE2 1 
ATOM   7747  N N   . SER E 1 250 ? -70.766  24.708  24.151  1.00 63.13  ? 457 SER E N   1 
ATOM   7748  C CA  . SER E 1 250 ? -70.772  24.365  22.735  1.00 63.26  ? 457 SER E CA  1 
ATOM   7749  C C   . SER E 1 250 ? -71.620  23.114  22.532  1.00 68.11  ? 457 SER E C   1 
ATOM   7750  O O   . SER E 1 250 ? -71.120  22.003  22.711  1.00 66.97  ? 457 SER E O   1 
ATOM   7751  C CB  . SER E 1 250 ? -69.332  24.146  22.258  1.00 68.36  ? 457 SER E CB  1 
ATOM   7752  O OG  . SER E 1 250 ? -69.249  23.835  20.876  1.00 78.30  ? 457 SER E OG  1 
ATOM   7753  N N   . GLY E 1 251 ? -72.887  23.271  22.134  1.00 64.35  ? 458 GLY E N   1 
ATOM   7754  C CA  . GLY E 1 251 ? -73.675  22.092  21.803  1.00 65.93  ? 458 GLY E CA  1 
ATOM   7755  C C   . GLY E 1 251 ? -75.150  22.123  22.162  1.00 70.92  ? 458 GLY E C   1 
ATOM   7756  O O   . GLY E 1 251 ? -75.836  23.106  21.876  1.00 69.45  ? 458 GLY E O   1 
ATOM   7757  N N   . ASP E 1 252 ? -75.655  21.053  22.785  1.00 72.84  ? 459 ASP E N   1 
ATOM   7758  C CA  . ASP E 1 252 ? -77.072  20.959  23.148  1.00 74.90  ? 459 ASP E CA  1 
ATOM   7759  C C   . ASP E 1 252 ? -77.336  20.531  24.603  1.00 79.56  ? 459 ASP E C   1 
ATOM   7760  O O   . ASP E 1 252 ? -76.455  20.032  25.309  1.00 77.96  ? 459 ASP E O   1 
ATOM   7761  C CB  . ASP E 1 252 ? -77.774  19.990  22.208  1.00 79.85  ? 459 ASP E CB  1 
ATOM   7762  C CG  . ASP E 1 252 ? -76.997  18.717  22.024  1.00 82.85  ? 459 ASP E CG  1 
ATOM   7763  O OD1 . ASP E 1 252 ? -76.557  18.158  23.045  1.00 85.18  ? 459 ASP E OD1 1 
ATOM   7764  O OD2 . ASP E 1 252 ? -76.830  18.269  20.871  1.00 89.81  ? 459 ASP E OD2 1 
ATOM   7765  N N   . HIS E 1 254 ? -78.176  17.613  25.513  1.00 81.40  ? 461 HIS E N   1 
ATOM   7766  C CA  . HIS E 1 254 ? -77.470  16.345  25.624  1.00 77.82  ? 461 HIS E CA  1 
ATOM   7767  C C   . HIS E 1 254 ? -76.001  16.568  25.932  1.00 84.47  ? 461 HIS E C   1 
ATOM   7768  O O   . HIS E 1 254 ? -75.600  16.558  27.090  1.00 107.31 ? 461 HIS E O   1 
ATOM   7769  C CB  . HIS E 1 254 ? -77.556  15.513  24.346  1.00 86.84  ? 461 HIS E CB  1 
ATOM   7770  C CG  . HIS E 1 254 ? -78.898  15.520  23.683  1.00 95.08  ? 461 HIS E CG  1 
ATOM   7771  N ND1 . HIS E 1 254 ? -79.115  16.112  22.455  1.00 97.10  ? 461 HIS E ND1 1 
ATOM   7772  C CD2 . HIS E 1 254 ? -80.078  14.964  24.049  1.00 99.82  ? 461 HIS E CD2 1 
ATOM   7773  C CE1 . HIS E 1 254 ? -80.378  15.945  22.107  1.00 100.41 ? 461 HIS E CE1 1 
ATOM   7774  N NE2 . HIS E 1 254 ? -80.983  15.252  23.056  1.00 105.20 ? 461 HIS E NE2 1 
ATOM   7775  N N   . GLY E 1 255 ? -75.210  16.751  24.870  1.00 80.62  ? 462 GLY E N   1 
ATOM   7776  C CA  . GLY E 1 255 ? -73.769  16.835  24.963  1.00 79.05  ? 462 GLY E CA  1 
ATOM   7777  C C   . GLY E 1 255 ? -73.208  18.181  24.527  1.00 77.55  ? 462 GLY E C   1 
ATOM   7778  O O   . GLY E 1 255 ? -73.941  19.106  24.162  1.00 77.85  ? 462 GLY E O   1 
ATOM   7779  N N   . GLY E 1 256 ? -71.886  18.277  24.586  1.00 73.18  ? 463 GLY E N   1 
ATOM   7780  C CA  . GLY E 1 256 ? -71.235  19.511  24.208  1.00 67.74  ? 463 GLY E CA  1 
ATOM   7781  C C   . GLY E 1 256 ? -69.901  19.697  24.904  1.00 63.20  ? 463 GLY E C   1 
ATOM   7782  O O   . GLY E 1 256 ? -69.345  18.770  25.502  1.00 59.46  ? 463 GLY E O   1 
ATOM   7783  N N   . HIS E 1 257 ? -69.370  20.923  24.804  1.00 65.79  ? 464 HIS E N   1 
ATOM   7784  C CA  . HIS E 1 257 ? -68.022  21.225  25.358  1.00 61.43  ? 464 HIS E CA  1 
ATOM   7785  C C   . HIS E 1 257 ? -68.006  22.602  26.022  1.00 55.87  ? 464 HIS E C   1 
ATOM   7786  O O   . HIS E 1 257 ? -68.754  23.475  25.582  1.00 49.84  ? 464 HIS E O   1 
ATOM   7787  C CB  . HIS E 1 257 ? -66.974  21.117  24.244  1.00 58.03  ? 464 HIS E CB  1 
ATOM   7788  C CG  . HIS E 1 257 ? -65.583  21.470  24.641  1.00 58.80  ? 464 HIS E CG  1 
ATOM   7789  N ND1 . HIS E 1 257 ? -64.742  20.568  25.251  1.00 56.05  ? 464 HIS E ND1 1 
ATOM   7790  C CD2 . HIS E 1 257 ? -64.878  22.611  24.503  1.00 58.24  ? 464 HIS E CD2 1 
ATOM   7791  C CE1 . HIS E 1 257 ? -63.583  21.142  25.485  1.00 52.05  ? 464 HIS E CE1 1 
ATOM   7792  N NE2 . HIS E 1 257 ? -63.644  22.393  25.040  1.00 57.19  ? 464 HIS E NE2 1 
ATOM   7793  N N   . TYR E 1 258 ? -67.166  22.771  27.040  1.00 59.06  ? 465 TYR E N   1 
ATOM   7794  C CA  . TYR E 1 258 ? -67.109  24.044  27.792  1.00 58.18  ? 465 TYR E CA  1 
ATOM   7795  C C   . TYR E 1 258 ? -65.763  24.741  27.602  1.00 59.00  ? 465 TYR E C   1 
ATOM   7796  O O   . TYR E 1 258 ? -64.727  24.065  27.609  1.00 58.93  ? 465 TYR E O   1 
ATOM   7797  C CB  . TYR E 1 258 ? -67.358  23.784  29.274  1.00 48.06  ? 465 TYR E CB  1 
ATOM   7798  C CG  . TYR E 1 258 ? -68.777  23.953  29.736  1.00 53.47  ? 465 TYR E CG  1 
ATOM   7799  C CD1 . TYR E 1 258 ? -69.404  25.184  29.685  1.00 57.74  ? 465 TYR E CD1 1 
ATOM   7800  C CD2 . TYR E 1 258 ? -69.482  22.881  30.247  1.00 56.01  ? 465 TYR E CD2 1 
ATOM   7801  C CE1 . TYR E 1 258 ? -70.708  25.343  30.118  1.00 57.38  ? 465 TYR E CE1 1 
ATOM   7802  C CE2 . TYR E 1 258 ? -70.783  23.025  30.688  1.00 54.56  ? 465 TYR E CE2 1 
ATOM   7803  C CZ  . TYR E 1 258 ? -71.399  24.258  30.620  1.00 57.41  ? 465 TYR E CZ  1 
ATOM   7804  O OH  . TYR E 1 258 ? -72.679  24.394  31.059  1.00 55.53  ? 465 TYR E OH  1 
ATOM   7805  N N   . VAL E 1 259 ? -65.793  26.064  27.467  1.00 59.93  ? 466 VAL E N   1 
ATOM   7806  C CA  . VAL E 1 259 ? -64.572  26.897  27.295  1.00 56.23  ? 466 VAL E CA  1 
ATOM   7807  C C   . VAL E 1 259 ? -64.811  28.157  28.124  1.00 55.40  ? 466 VAL E C   1 
ATOM   7808  O O   . VAL E 1 259 ? -65.959  28.521  28.309  1.00 59.38  ? 466 VAL E O   1 
ATOM   7809  C CB  . VAL E 1 259 ? -64.357  27.204  25.801  1.00 60.07  ? 466 VAL E CB  1 
ATOM   7810  C CG1 . VAL E 1 259 ? -63.742  28.563  25.508  1.00 63.16  ? 466 VAL E CG1 1 
ATOM   7811  C CG2 . VAL E 1 259 ? -63.592  26.107  25.092  1.00 55.78  ? 466 VAL E CG2 1 
ATOM   7812  N N   . VAL E 1 260 ? -63.764  28.777  28.642  1.00 57.01  ? 467 VAL E N   1 
ATOM   7813  C CA  . VAL E 1 260 ? -63.909  30.017  29.406  1.00 60.46  ? 467 VAL E CA  1 
ATOM   7814  C C   . VAL E 1 260 ? -62.977  31.095  28.840  1.00 64.05  ? 467 VAL E C   1 
ATOM   7815  O O   . VAL E 1 260 ? -61.761  30.887  28.730  1.00 64.35  ? 467 VAL E O   1 
ATOM   7816  C CB  . VAL E 1 260 ? -63.661  29.790  30.913  1.00 53.31  ? 467 VAL E CB  1 
ATOM   7817  C CG1 . VAL E 1 260 ? -62.268  29.222  31.181  1.00 55.16  ? 467 VAL E CG1 1 
ATOM   7818  C CG2 . VAL E 1 260 ? -63.904  31.070  31.695  1.00 55.97  ? 467 VAL E CG2 1 
ATOM   7819  N N   . TYR E 1 261 ? -63.555  32.238  28.473  1.00 58.68  ? 468 TYR E N   1 
ATOM   7820  C CA  . TYR E 1 261 ? -62.803  33.448  28.156  1.00 63.85  ? 468 TYR E CA  1 
ATOM   7821  C C   . TYR E 1 261 ? -62.632  34.319  29.406  1.00 66.75  ? 468 TYR E C   1 
ATOM   7822  O O   . TYR E 1 261 ? -63.566  34.481  30.198  1.00 64.91  ? 468 TYR E O   1 
ATOM   7823  C CB  . TYR E 1 261 ? -63.516  34.241  27.050  1.00 63.13  ? 468 TYR E CB  1 
ATOM   7824  C CG  . TYR E 1 261 ? -63.613  33.499  25.740  1.00 66.18  ? 468 TYR E CG  1 
ATOM   7825  C CD1 . TYR E 1 261 ? -62.508  33.386  24.897  1.00 73.11  ? 468 TYR E CD1 1 
ATOM   7826  C CD2 . TYR E 1 261 ? -64.800  32.895  25.342  1.00 71.62  ? 468 TYR E CD2 1 
ATOM   7827  C CE1 . TYR E 1 261 ? -62.581  32.690  23.689  1.00 68.82  ? 468 TYR E CE1 1 
ATOM   7828  C CE2 . TYR E 1 261 ? -64.884  32.197  24.133  1.00 72.09  ? 468 TYR E CE2 1 
ATOM   7829  C CZ  . TYR E 1 261 ? -63.765  32.102  23.316  1.00 73.21  ? 468 TYR E CZ  1 
ATOM   7830  O OH  . TYR E 1 261 ? -63.819  31.424  22.123  1.00 77.33  ? 468 TYR E OH  1 
ATOM   7831  N N   . LEU E 1 262 ? -61.422  34.847  29.592  1.00 65.79  ? 469 LEU E N   1 
ATOM   7832  C CA  . LEU E 1 262 ? -61.139  35.588  30.843  1.00 63.31  ? 469 LEU E CA  1 
ATOM   7833  C C   . LEU E 1 262 ? -60.123  36.706  30.640  1.00 69.62  ? 469 LEU E C   1 
ATOM   7834  O O   . LEU E 1 262 ? -59.162  36.487  29.896  1.00 77.54  ? 469 LEU E O   1 
ATOM   7835  C CB  . LEU E 1 262 ? -60.556  34.580  31.834  1.00 62.94  ? 469 LEU E CB  1 
ATOM   7836  C CG  . LEU E 1 262 ? -61.400  34.228  33.052  1.00 62.30  ? 469 LEU E CG  1 
ATOM   7837  C CD1 . LEU E 1 262 ? -61.135  32.793  33.463  1.00 60.67  ? 469 LEU E CD1 1 
ATOM   7838  C CD2 . LEU E 1 262 ? -61.088  35.166  34.202  1.00 56.04  ? 469 LEU E CD2 1 
ATOM   7839  N N   . ASN E 1 263 ? -60.347  37.865  31.260  1.00 67.38  ? 470 ASN E N   1 
ATOM   7840  C CA  . ASN E 1 263 ? -59.322  38.944  31.293  1.00 69.12  ? 470 ASN E CA  1 
ATOM   7841  C C   . ASN E 1 263 ? -58.869  38.920  32.753  1.00 66.97  ? 470 ASN E C   1 
ATOM   7842  O O   . ASN E 1 263 ? -59.427  39.665  33.563  1.00 63.17  ? 470 ASN E O   1 
ATOM   7843  C CB  . ASN E 1 263 ? -59.811  40.275  30.700  1.00 72.87  ? 470 ASN E CB  1 
ATOM   7844  C CG  . ASN E 1 263 ? -60.971  40.953  31.397  1.00 75.08  ? 470 ASN E CG  1 
ATOM   7845  O OD1 . ASN E 1 263 ? -60.865  42.109  31.786  1.00 71.64  ? 470 ASN E OD1 1 
ATOM   7846  N ND2 . ASN E 1 263 ? -62.087  40.265  31.534  1.00 70.00  ? 470 ASN E ND2 1 
ATOM   7847  N N   . PRO E 1 264 ? -57.884  38.080  33.133  1.00 66.34  ? 471 PRO E N   1 
ATOM   7848  C CA  . PRO E 1 264 ? -57.566  37.869  34.553  1.00 65.35  ? 471 PRO E CA  1 
ATOM   7849  C C   . PRO E 1 264 ? -57.209  39.089  35.412  1.00 70.67  ? 471 PRO E C   1 
ATOM   7850  O O   . PRO E 1 264 ? -57.195  38.938  36.615  1.00 69.63  ? 471 PRO E O   1 
ATOM   7851  C CB  . PRO E 1 264 ? -56.329  36.970  34.443  1.00 63.90  ? 471 PRO E CB  1 
ATOM   7852  C CG  . PRO E 1 264 ? -56.526  36.238  33.151  1.00 66.40  ? 471 PRO E CG  1 
ATOM   7853  C CD  . PRO E 1 264 ? -56.988  37.346  32.241  1.00 65.66  ? 471 PRO E CD  1 
ATOM   7854  N N   . LYS E 1 265 ? -56.939  40.241  34.796  1.00 75.05  ? 472 LYS E N   1 
ATOM   7855  C CA  . LYS E 1 265 ? -56.493  41.435  35.555  1.00 70.45  ? 472 LYS E CA  1 
ATOM   7856  C C   . LYS E 1 265 ? -57.512  42.565  35.439  1.00 65.28  ? 472 LYS E C   1 
ATOM   7857  O O   . LYS E 1 265 ? -57.342  43.561  36.148  1.00 73.90  ? 472 LYS E O   1 
ATOM   7858  C CB  . LYS E 1 265 ? -55.129  41.885  35.034  1.00 63.58  ? 472 LYS E CB  1 
ATOM   7859  N N   . GLY E 1 266 ? -58.515  42.425  34.579  1.00 59.28  ? 473 GLY E N   1 
ATOM   7860  C CA  . GLY E 1 266 ? -59.544  43.441  34.525  1.00 64.43  ? 473 GLY E CA  1 
ATOM   7861  C C   . GLY E 1 266 ? -59.272  44.589  33.587  1.00 70.39  ? 473 GLY E C   1 
ATOM   7862  O O   . GLY E 1 266 ? -59.901  45.642  33.725  1.00 73.76  ? 473 GLY E O   1 
ATOM   7863  N N   . ASP E 1 267 ? -58.361  44.419  32.624  1.00 72.28  ? 474 ASP E N   1 
ATOM   7864  C CA  . ASP E 1 267 ? -57.991  45.477  31.686  1.00 73.42  ? 474 ASP E CA  1 
ATOM   7865  C C   . ASP E 1 267 ? -58.742  45.393  30.352  1.00 80.79  ? 474 ASP E C   1 
ATOM   7866  O O   . ASP E 1 267 ? -59.286  46.395  29.871  1.00 87.76  ? 474 ASP E O   1 
ATOM   7867  C CB  . ASP E 1 267 ? -56.480  45.440  31.455  1.00 69.40  ? 474 ASP E CB  1 
ATOM   7868  C CG  . ASP E 1 267 ? -55.947  44.037  31.375  1.00 68.99  ? 474 ASP E CG  1 
ATOM   7869  O OD1 . ASP E 1 267 ? -56.522  43.242  30.612  1.00 72.45  ? 474 ASP E OD1 1 
ATOM   7870  O OD2 . ASP E 1 267 ? -54.972  43.721  32.089  1.00 66.59  ? 474 ASP E OD2 1 
ATOM   7871  N N   . GLY E 1 268 ? -58.791  44.221  29.740  1.00 75.91  ? 475 GLY E N   1 
ATOM   7872  C CA  . GLY E 1 268 ? -59.371  44.107  28.423  1.00 69.46  ? 475 GLY E CA  1 
ATOM   7873  C C   . GLY E 1 268 ? -58.440  43.291  27.560  1.00 72.91  ? 475 GLY E C   1 
ATOM   7874  O O   . GLY E 1 268 ? -58.640  43.173  26.350  1.00 76.95  ? 475 GLY E O   1 
ATOM   7875  N N   . LYS E 1 269 ? -57.401  42.740  28.188  1.00 71.68  ? 476 LYS E N   1 
ATOM   7876  C CA  . LYS E 1 269 ? -56.448  41.848  27.535  1.00 65.99  ? 476 LYS E CA  1 
ATOM   7877  C C   . LYS E 1 269 ? -56.948  40.430  27.773  1.00 74.49  ? 476 LYS E C   1 
ATOM   7878  O O   . LYS E 1 269 ? -56.692  39.835  28.821  1.00 74.89  ? 476 LYS E O   1 
ATOM   7879  C CB  . LYS E 1 269 ? -55.040  42.063  28.082  1.00 64.88  ? 476 LYS E CB  1 
ATOM   7880  N N   . TRP E 1 270 ? -57.728  39.946  26.803  1.00 77.52  ? 477 TRP E N   1 
ATOM   7881  C CA  . TRP E 1 270 ? -58.447  38.658  26.957  1.00 70.91  ? 477 TRP E CA  1 
ATOM   7882  C C   . TRP E 1 270 ? -57.640  37.429  26.568  1.00 71.38  ? 477 TRP E C   1 
ATOM   7883  O O   . TRP E 1 270 ? -56.707  37.555  25.768  1.00 76.56  ? 477 TRP E O   1 
ATOM   7884  C CB  . TRP E 1 270 ? -59.710  38.725  26.104  1.00 65.27  ? 477 TRP E CB  1 
ATOM   7885  C CG  . TRP E 1 270 ? -60.782  39.584  26.689  1.00 70.38  ? 477 TRP E CG  1 
ATOM   7886  C CD1 . TRP E 1 270 ? -60.945  40.929  26.537  1.00 72.87  ? 477 TRP E CD1 1 
ATOM   7887  C CD2 . TRP E 1 270 ? -61.854  39.141  27.530  1.00 74.65  ? 477 TRP E CD2 1 
ATOM   7888  N NE1 . TRP E 1 270 ? -62.044  41.354  27.230  1.00 79.34  ? 477 TRP E NE1 1 
ATOM   7889  C CE2 . TRP E 1 270 ? -62.622  40.277  27.846  1.00 78.48  ? 477 TRP E CE2 1 
ATOM   7890  C CE3 . TRP E 1 270 ? -62.237  37.898  28.039  1.00 70.26  ? 477 TRP E CE3 1 
ATOM   7891  C CZ2 . TRP E 1 270 ? -63.751  40.198  28.653  1.00 72.88  ? 477 TRP E CZ2 1 
ATOM   7892  C CZ3 . TRP E 1 270 ? -63.354  37.822  28.836  1.00 71.41  ? 477 TRP E CZ3 1 
ATOM   7893  C CH2 . TRP E 1 270 ? -64.094  38.958  29.139  1.00 71.24  ? 477 TRP E CH2 1 
ATOM   7894  N N   . CYS E 1 271 ? -58.057  36.279  27.091  1.00 72.37  ? 478 CYS E N   1 
ATOM   7895  C CA  . CYS E 1 271 ? -57.399  34.992  26.779  1.00 70.58  ? 478 CYS E CA  1 
ATOM   7896  C C   . CYS E 1 271 ? -58.468  33.891  26.759  1.00 71.09  ? 478 CYS E C   1 
ATOM   7897  O O   . CYS E 1 271 ? -59.454  34.023  27.495  1.00 70.43  ? 478 CYS E O   1 
ATOM   7898  C CB  . CYS E 1 271 ? -56.344  34.667  27.828  1.00 71.07  ? 478 CYS E CB  1 
ATOM   7899  S SG  . CYS E 1 271 ? -54.841  35.670  27.728  1.00 87.64  ? 478 CYS E SG  1 
ATOM   7900  N N   . LYS E 1 272 ? -58.282  32.853  25.943  1.00 66.74  ? 479 LYS E N   1 
ATOM   7901  C CA  . LYS E 1 272 ? -59.218  31.704  25.879  1.00 62.03  ? 479 LYS E CA  1 
ATOM   7902  C C   . LYS E 1 272 ? -58.604  30.505  26.582  1.00 65.59  ? 479 LYS E C   1 
ATOM   7903  O O   . LYS E 1 272 ? -57.398  30.310  26.451  1.00 68.71  ? 479 LYS E O   1 
ATOM   7904  C CB  . LYS E 1 272 ? -59.442  31.270  24.435  1.00 69.45  ? 479 LYS E CB  1 
ATOM   7905  N N   . PHE E 1 273 ? -59.424  29.719  27.275  1.00 68.92  ? 480 PHE E N   1 
ATOM   7906  C CA  . PHE E 1 273 ? -58.907  28.564  28.049  1.00 66.46  ? 480 PHE E CA  1 
ATOM   7907  C C   . PHE E 1 273 ? -59.670  27.300  27.635  1.00 72.79  ? 480 PHE E C   1 
ATOM   7908  O O   . PHE E 1 273 ? -60.674  26.981  28.292  1.00 73.35  ? 480 PHE E O   1 
ATOM   7909  C CB  . PHE E 1 273 ? -59.001  28.855  29.548  1.00 66.65  ? 480 PHE E CB  1 
ATOM   7910  C CG  . PHE E 1 273 ? -58.192  30.018  30.065  1.00 66.96  ? 480 PHE E CG  1 
ATOM   7911  C CD1 . PHE E 1 273 ? -58.655  31.319  29.959  1.00 65.24  ? 480 PHE E CD1 1 
ATOM   7912  C CD2 . PHE E 1 273 ? -56.982  29.808  30.700  1.00 64.94  ? 480 PHE E CD2 1 
ATOM   7913  C CE1 . PHE E 1 273 ? -57.908  32.382  30.436  1.00 63.24  ? 480 PHE E CE1 1 
ATOM   7914  C CE2 . PHE E 1 273 ? -56.239  30.871  31.187  1.00 64.96  ? 480 PHE E CE2 1 
ATOM   7915  C CZ  . PHE E 1 273 ? -56.702  32.157  31.052  1.00 63.01  ? 480 PHE E CZ  1 
ATOM   7916  N N   . ASP E 1 274 ? -59.225  26.626  26.569  1.00 72.76  ? 481 ASP E N   1 
ATOM   7917  C CA  . ASP E 1 274 ? -59.846  25.356  26.108  1.00 69.35  ? 481 ASP E CA  1 
ATOM   7918  C C   . ASP E 1 274 ? -59.018  24.225  26.696  1.00 70.57  ? 481 ASP E C   1 
ATOM   7919  O O   . ASP E 1 274 ? -58.065  23.796  26.033  1.00 76.10  ? 481 ASP E O   1 
ATOM   7920  C CB  . ASP E 1 274 ? -59.920  25.277  24.581  1.00 72.00  ? 481 ASP E CB  1 
ATOM   7921  C CG  . ASP E 1 274 ? -60.772  24.156  24.009  1.00 70.82  ? 481 ASP E CG  1 
ATOM   7922  O OD1 . ASP E 1 274 ? -60.698  23.026  24.520  1.00 59.26  ? 481 ASP E OD1 1 
ATOM   7923  O OD2 . ASP E 1 274 ? -61.490  24.421  23.029  1.00 71.55  ? 481 ASP E OD2 1 
ATOM   7924  N N   . ASP E 1 275 ? -59.368  23.788  27.899  1.00 69.77  ? 482 ASP E N   1 
ATOM   7925  C CA  . ASP E 1 275 ? -58.626  22.711  28.598  1.00 68.11  ? 482 ASP E CA  1 
ATOM   7926  C C   . ASP E 1 275 ? -57.125  22.988  28.536  1.00 72.44  ? 482 ASP E C   1 
ATOM   7927  O O   . ASP E 1 275 ? -56.712  24.025  29.074  1.00 73.61  ? 482 ASP E O   1 
ATOM   7928  C CB  . ASP E 1 275 ? -59.021  21.325  28.080  1.00 67.72  ? 482 ASP E CB  1 
ATOM   7929  C CG  . ASP E 1 275 ? -60.479  20.971  28.300  1.00 69.19  ? 482 ASP E CG  1 
ATOM   7930  O OD1 . ASP E 1 275 ? -61.048  21.427  29.304  1.00 66.82  ? 482 ASP E OD1 1 
ATOM   7931  O OD2 . ASP E 1 275 ? -61.028  20.237  27.463  1.00 64.42  ? 482 ASP E OD2 1 
ATOM   7932  N N   . ASP E 1 276 ? -56.348  22.096  27.918  1.00 71.45  ? 483 ASP E N   1 
ATOM   7933  C CA  . ASP E 1 276 ? -54.861  22.199  27.900  1.00 73.05  ? 483 ASP E CA  1 
ATOM   7934  C C   . ASP E 1 276 ? -54.342  23.402  27.115  1.00 71.15  ? 483 ASP E C   1 
ATOM   7935  O O   . ASP E 1 276 ? -53.157  23.714  27.280  1.00 78.68  ? 483 ASP E O   1 
ATOM   7936  C CB  . ASP E 1 276 ? -54.244  20.920  27.332  1.00 72.30  ? 483 ASP E CB  1 
ATOM   7937  C CG  . ASP E 1 276 ? -54.665  20.588  25.911  1.00 72.64  ? 483 ASP E CG  1 
ATOM   7938  O OD1 . ASP E 1 276 ? -55.878  20.476  25.664  1.00 75.40  ? 483 ASP E OD1 1 
ATOM   7939  O OD2 . ASP E 1 276 ? -53.770  20.428  25.066  1.00 73.63  ? 483 ASP E OD2 1 
ATOM   7940  N N   . VAL E 1 277 ? -55.167  24.048  26.300  1.00 63.24  ? 484 VAL E N   1 
ATOM   7941  C CA  . VAL E 1 277 ? -54.617  25.131  25.436  1.00 72.96  ? 484 VAL E CA  1 
ATOM   7942  C C   . VAL E 1 277 ? -55.084  26.498  25.922  1.00 71.95  ? 484 VAL E C   1 
ATOM   7943  O O   . VAL E 1 277 ? -56.296  26.687  26.084  1.00 69.55  ? 484 VAL E O   1 
ATOM   7944  C CB  . VAL E 1 277 ? -54.969  24.915  23.952  1.00 72.30  ? 484 VAL E CB  1 
ATOM   7945  C CG1 . VAL E 1 277 ? -54.455  26.039  23.066  1.00 60.54  ? 484 VAL E CG1 1 
ATOM   7946  C CG2 . VAL E 1 277 ? -54.476  23.572  23.441  1.00 71.69  ? 484 VAL E CG2 1 
ATOM   7947  N N   . VAL E 1 278 ? -54.135  27.400  26.156  1.00 71.97  ? 485 VAL E N   1 
ATOM   7948  C CA  . VAL E 1 278 ? -54.480  28.799  26.521  1.00 67.36  ? 485 VAL E CA  1 
ATOM   7949  C C   . VAL E 1 278 ? -54.058  29.678  25.351  1.00 67.43  ? 485 VAL E C   1 
ATOM   7950  O O   . VAL E 1 278 ? -52.862  29.696  25.029  1.00 70.72  ? 485 VAL E O   1 
ATOM   7951  C CB  . VAL E 1 278 ? -53.803  29.229  27.827  1.00 71.36  ? 485 VAL E CB  1 
ATOM   7952  C CG1 . VAL E 1 278 ? -54.079  30.689  28.150  1.00 68.55  ? 485 VAL E CG1 1 
ATOM   7953  C CG2 . VAL E 1 278 ? -54.242  28.344  28.970  1.00 69.08  ? 485 VAL E CG2 1 
ATOM   7954  N N   . SER E 1 279 ? -55.025  30.344  24.727  1.00 67.45  ? 486 SER E N   1 
ATOM   7955  C CA  . SER E 1 279 ? -54.746  31.217  23.563  1.00 64.71  ? 486 SER E CA  1 
ATOM   7956  C C   . SER E 1 279 ? -55.058  32.665  23.915  1.00 66.86  ? 486 SER E C   1 
ATOM   7957  O O   . SER E 1 279 ? -55.848  32.883  24.817  1.00 68.32  ? 486 SER E O   1 
ATOM   7958  C CB  . SER E 1 279 ? -55.548  30.766  22.370  1.00 67.10  ? 486 SER E CB  1 
ATOM   7959  O OG  . SER E 1 279 ? -56.547  31.706  22.001  1.00 66.58  ? 486 SER E OG  1 
ATOM   7960  N N   . ARG E 1 280 ? -54.440  33.611  23.219  1.00 65.88  ? 487 ARG E N   1 
ATOM   7961  C CA  . ARG E 1 280 ? -54.803  35.034  23.427  1.00 64.51  ? 487 ARG E CA  1 
ATOM   7962  C C   . ARG E 1 280 ? -56.013  35.344  22.544  1.00 63.35  ? 487 ARG E C   1 
ATOM   7963  O O   . ARG E 1 280 ? -56.151  34.721  21.477  1.00 57.13  ? 487 ARG E O   1 
ATOM   7964  C CB  . ARG E 1 280 ? -53.607  35.944  23.156  1.00 53.83  ? 487 ARG E CB  1 
ATOM   7965  N N   . CYS E 1 281 ? -56.846  36.289  22.966  1.00 63.31  ? 488 CYS E N   1 
ATOM   7966  C CA  . CYS E 1 281 ? -58.109  36.519  22.231  1.00 67.57  ? 488 CYS E CA  1 
ATOM   7967  C C   . CYS E 1 281 ? -58.384  37.996  21.990  1.00 67.04  ? 488 CYS E C   1 
ATOM   7968  O O   . CYS E 1 281 ? -57.679  38.840  22.560  1.00 65.76  ? 488 CYS E O   1 
ATOM   7969  C CB  . CYS E 1 281 ? -59.278  35.979  23.046  1.00 66.41  ? 488 CYS E CB  1 
ATOM   7970  N N   . THR E 1 282 ? -59.388  38.269  21.166  1.00 66.70  ? 489 THR E N   1 
ATOM   7971  C CA  . THR E 1 282 ? -59.808  39.665  20.933  1.00 75.04  ? 489 THR E CA  1 
ATOM   7972  C C   . THR E 1 282 ? -60.977  39.953  21.870  1.00 72.88  ? 489 THR E C   1 
ATOM   7973  O O   . THR E 1 282 ? -61.550  38.999  22.414  1.00 71.37  ? 489 THR E O   1 
ATOM   7974  C CB  . THR E 1 282 ? -60.164  39.900  19.458  1.00 79.72  ? 489 THR E CB  1 
ATOM   7975  O OG1 . THR E 1 282 ? -61.572  39.786  19.253  1.00 73.84  ? 489 THR E OG1 1 
ATOM   7976  C CG2 . THR E 1 282 ? -59.455  38.952  18.514  1.00 78.25  ? 489 THR E CG2 1 
ATOM   7977  N N   . LYS E 1 283 ? -61.321  41.224  22.045  1.00 72.77  ? 490 LYS E N   1 
ATOM   7978  C CA  . LYS E 1 283 ? -62.519  41.547  22.857  1.00 76.31  ? 490 LYS E CA  1 
ATOM   7979  C C   . LYS E 1 283 ? -63.728  40.901  22.178  1.00 79.69  ? 490 LYS E C   1 
ATOM   7980  O O   . LYS E 1 283 ? -64.439  40.162  22.846  1.00 78.52  ? 490 LYS E O   1 
ATOM   7981  C CB  . LYS E 1 283 ? -62.681  43.059  23.013  1.00 69.53  ? 490 LYS E CB  1 
ATOM   7982  N N   . GLU E 1 284 ? -63.895  41.117  20.877  1.00 78.40  ? 491 GLU E N   1 
ATOM   7983  C CA  . GLU E 1 284 ? -65.042  40.543  20.134  1.00 74.79  ? 491 GLU E CA  1 
ATOM   7984  C C   . GLU E 1 284 ? -65.027  39.019  20.221  1.00 76.24  ? 491 GLU E C   1 
ATOM   7985  O O   . GLU E 1 284 ? -66.098  38.459  20.456  1.00 78.64  ? 491 GLU E O   1 
ATOM   7986  C CB  . GLU E 1 284 ? -64.983  40.970  18.670  1.00 75.25  ? 491 GLU E CB  1 
ATOM   7987  N N   . GLU E 1 285 ? -63.864  38.382  20.074  1.00 77.01  ? 492 GLU E N   1 
ATOM   7988  C CA  . GLU E 1 285 ? -63.778  36.892  20.043  1.00 79.55  ? 492 GLU E CA  1 
ATOM   7989  C C   . GLU E 1 285 ? -64.103  36.271  21.408  1.00 75.88  ? 492 GLU E C   1 
ATOM   7990  O O   . GLU E 1 285 ? -64.196  35.039  21.474  1.00 74.56  ? 492 GLU E O   1 
ATOM   7991  C CB  . GLU E 1 285 ? -62.394  36.462  19.552  1.00 72.06  ? 492 GLU E CB  1 
ATOM   7992  N N   . ALA E 1 286 ? -64.280  37.087  22.440  1.00 72.77  ? 493 ALA E N   1 
ATOM   7993  C CA  . ALA E 1 286 ? -64.626  36.593  23.783  1.00 67.36  ? 493 ALA E CA  1 
ATOM   7994  C C   . ALA E 1 286 ? -65.978  37.159  24.184  1.00 70.39  ? 493 ALA E C   1 
ATOM   7995  O O   . ALA E 1 286 ? -66.627  36.582  25.061  1.00 71.54  ? 493 ALA E O   1 
ATOM   7996  C CB  . ALA E 1 286 ? -63.581  37.072  24.731  1.00 66.43  ? 493 ALA E CB  1 
ATOM   7997  N N   . ILE E 1 287 ? -66.356  38.276  23.578  1.00 71.35  ? 494 ILE E N   1 
ATOM   7998  C CA  . ILE E 1 287 ? -67.629  38.940  23.951  1.00 72.73  ? 494 ILE E CA  1 
ATOM   7999  C C   . ILE E 1 287 ? -68.597  38.791  22.781  1.00 75.12  ? 494 ILE E C   1 
ATOM   8000  O O   . ILE E 1 287 ? -69.318  37.798  22.786  1.00 74.43  ? 494 ILE E O   1 
ATOM   8001  C CB  . ILE E 1 287 ? -67.366  40.403  24.363  1.00 74.67  ? 494 ILE E CB  1 
ATOM   8002  C CG1 . ILE E 1 287 ? -66.265  40.501  25.419  1.00 70.74  ? 494 ILE E CG1 1 
ATOM   8003  C CG2 . ILE E 1 287 ? -68.627  41.078  24.862  1.00 70.60  ? 494 ILE E CG2 1 
ATOM   8004  C CD1 . ILE E 1 287 ? -65.768  41.902  25.643  1.00 72.05  ? 494 ILE E CD1 1 
ATOM   8005  N N   . GLU E 1 288 ? -68.556  39.678  21.789  1.00 77.50  ? 495 GLU E N   1 
ATOM   8006  C CA  . GLU E 1 288 ? -69.560  39.686  20.686  1.00 75.46  ? 495 GLU E CA  1 
ATOM   8007  C C   . GLU E 1 288 ? -69.727  38.304  20.039  1.00 75.36  ? 495 GLU E C   1 
ATOM   8008  O O   . GLU E 1 288 ? -70.863  37.964  19.689  1.00 70.35  ? 495 GLU E O   1 
ATOM   8009  C CB  . GLU E 1 288 ? -69.202  40.784  19.685  1.00 73.69  ? 495 GLU E CB  1 
ATOM   8010  C CG  . GLU E 1 288 ? -69.638  42.168  20.128  1.00 77.84  ? 495 GLU E CG  1 
ATOM   8011  C CD  . GLU E 1 288 ? -68.703  42.900  21.077  1.00 89.23  ? 495 GLU E CD  1 
ATOM   8012  O OE1 . GLU E 1 288 ? -67.543  42.470  21.224  1.00 85.00  ? 495 GLU E OE1 1 
ATOM   8013  O OE2 . GLU E 1 288 ? -69.139  43.905  21.667  1.00 92.13  ? 495 GLU E OE2 1 
ATOM   8014  N N   . HIS E 1 289 ? -68.647  37.548  19.875  1.00 71.31  ? 496 HIS E N   1 
ATOM   8015  C CA  . HIS E 1 289 ? -68.710  36.240  19.225  1.00 72.78  ? 496 HIS E CA  1 
ATOM   8016  C C   . HIS E 1 289 ? -69.385  35.161  20.080  1.00 74.38  ? 496 HIS E C   1 
ATOM   8017  O O   . HIS E 1 289 ? -69.565  34.035  19.604  1.00 72.61  ? 496 HIS E O   1 
ATOM   8018  C CB  . HIS E 1 289 ? -67.298  35.786  18.821  1.00 77.17  ? 496 HIS E CB  1 
ATOM   8019  N N   . ASN E 1 290 ? -69.766  35.462  21.322  1.00 75.67  ? 497 ASN E N   1 
ATOM   8020  C CA  . ASN E 1 290 ? -70.493  34.522  22.170  1.00 67.62  ? 497 ASN E CA  1 
ATOM   8021  C C   . ASN E 1 290 ? -71.856  35.065  22.548  1.00 66.99  ? 497 ASN E C   1 
ATOM   8022  O O   . ASN E 1 290 ? -72.400  34.682  23.592  1.00 66.87  ? 497 ASN E O   1 
ATOM   8023  C CB  . ASN E 1 290 ? -69.714  34.186  23.441  1.00 63.12  ? 497 ASN E CB  1 
ATOM   8024  C CG  . ASN E 1 290 ? -68.328  33.681  23.155  1.00 67.70  ? 497 ASN E CG  1 
ATOM   8025  O OD1 . ASN E 1 290 ? -68.143  32.739  22.391  1.00 68.25  ? 497 ASN E OD1 1 
ATOM   8026  N ND2 . ASN E 1 290 ? -67.337  34.297  23.785  1.00 65.67  ? 497 ASN E ND2 1 
ATOM   8027  N N   . TYR E 1 291 ? -72.389  35.991  21.742  1.00 68.34  ? 498 TYR E N   1 
ATOM   8028  C CA  . TYR E 1 291 ? -73.771  36.428  21.890  1.00 70.14  ? 498 TYR E CA  1 
ATOM   8029  C C   . TYR E 1 291 ? -74.728  35.413  21.285  1.00 64.06  ? 498 TYR E C   1 
ATOM   8030  O O   . TYR E 1 291 ? -75.895  35.378  21.673  1.00 66.83  ? 498 TYR E O   1 
ATOM   8031  C CB  . TYR E 1 291 ? -73.990  37.812  21.251  1.00 64.97  ? 498 TYR E CB  1 
ATOM   8032  C CG  . TYR E 1 291 ? -73.325  38.995  21.949  1.00 71.42  ? 498 TYR E CG  1 
ATOM   8033  C CD1 . TYR E 1 291 ? -72.214  38.830  22.771  1.00 74.44  ? 498 TYR E CD1 1 
ATOM   8034  C CD2 . TYR E 1 291 ? -73.777  40.301  21.723  1.00 71.70  ? 498 TYR E CD2 1 
ATOM   8035  C CE1 . TYR E 1 291 ? -71.602  39.920  23.397  1.00 75.83  ? 498 TYR E CE1 1 
ATOM   8036  C CE2 . TYR E 1 291 ? -73.169  41.400  22.341  1.00 68.50  ? 498 TYR E CE2 1 
ATOM   8037  C CZ  . TYR E 1 291 ? -72.081  41.202  23.170  1.00 75.48  ? 498 TYR E CZ  1 
ATOM   8038  O OH  . TYR E 1 291 ? -71.464  42.275  23.780  1.00 74.37  ? 498 TYR E OH  1 
ATOM   8039  N N   . GLY E 1 292 ? -74.253  34.591  20.356  1.00 60.78  ? 499 GLY E N   1 
ATOM   8040  C CA  . GLY E 1 292 ? -75.019  33.487  19.815  1.00 68.27  ? 499 GLY E CA  1 
ATOM   8041  C C   . GLY E 1 292 ? -76.012  33.912  18.746  1.00 68.25  ? 499 GLY E C   1 
ATOM   8042  O O   . GLY E 1 292 ? -76.384  35.073  18.620  1.00 66.36  ? 499 GLY E O   1 
ATOM   8043  N N   . GLY E 1 293 ? -76.437  32.944  17.943  1.00 68.88  ? 500 GLY E N   1 
ATOM   8044  C CA  . GLY E 1 293 ? -77.348  33.258  16.831  1.00 75.08  ? 500 GLY E CA  1 
ATOM   8045  C C   . GLY E 1 293 ? -76.773  32.794  15.506  1.00 89.44  ? 500 GLY E C   1 
ATOM   8046  O O   . GLY E 1 293 ? -75.615  33.160  15.225  1.00 91.51  ? 500 GLY E O   1 
ATOM   8047  N N   . ARG E 1 301 ? -70.641  26.513  15.668  1.00 89.57  ? 508 ARG E N   1 
ATOM   8048  C CA  . ARG E 1 301 ? -70.603  27.972  15.603  1.00 87.68  ? 508 ARG E CA  1 
ATOM   8049  C C   . ARG E 1 301 ? -71.950  28.566  16.012  1.00 89.72  ? 508 ARG E C   1 
ATOM   8050  O O   . ARG E 1 301 ? -72.023  29.401  16.917  1.00 82.20  ? 508 ARG E O   1 
ATOM   8051  C CB  . ARG E 1 301 ? -70.223  28.445  14.197  1.00 87.22  ? 508 ARG E CB  1 
ATOM   8052  N N   . HIS E 1 302 ? -73.019  28.135  15.334  1.00 90.90  ? 509 HIS E N   1 
ATOM   8053  C CA  . HIS E 1 302 ? -74.351  28.619  15.677  1.00 83.13  ? 509 HIS E CA  1 
ATOM   8054  C C   . HIS E 1 302 ? -74.720  28.234  17.105  1.00 85.64  ? 509 HIS E C   1 
ATOM   8055  O O   . HIS E 1 302 ? -75.311  29.038  17.838  1.00 80.89  ? 509 HIS E O   1 
ATOM   8056  C CB  . HIS E 1 302 ? -75.378  28.069  14.686  1.00 84.56  ? 509 HIS E CB  1 
ATOM   8057  N N   . CYS E 1 303 ? -74.345  27.016  17.524  1.00 84.81  ? 510 CYS E N   1 
ATOM   8058  C CA  . CYS E 1 303 ? -74.708  26.420  18.807  1.00 77.03  ? 510 CYS E CA  1 
ATOM   8059  C C   . CYS E 1 303 ? -73.731  26.772  19.937  1.00 73.39  ? 510 CYS E C   1 
ATOM   8060  O O   . CYS E 1 303 ? -73.661  26.044  20.937  1.00 70.73  ? 510 CYS E O   1 
ATOM   8061  C CB  . CYS E 1 303 ? -74.804  24.893  18.665  1.00 81.76  ? 510 CYS E CB  1 
ATOM   8062  S SG  . CYS E 1 303 ? -73.415  24.097  17.735  1.00 95.40  ? 510 CYS E SG  1 
ATOM   8063  N N   . THR E 1 304 ? -72.986  27.867  19.804  1.00 69.94  ? 511 THR E N   1 
ATOM   8064  C CA  . THR E 1 304 ? -71.952  28.230  20.760  1.00 66.42  ? 511 THR E CA  1 
ATOM   8065  C C   . THR E 1 304 ? -72.223  29.628  21.291  1.00 69.46  ? 511 THR E C   1 
ATOM   8066  O O   . THR E 1 304 ? -72.511  30.543  20.512  1.00 70.80  ? 511 THR E O   1 
ATOM   8067  C CB  . THR E 1 304 ? -70.572  28.154  20.118  1.00 65.04  ? 511 THR E CB  1 
ATOM   8068  O OG1 . THR E 1 304 ? -70.290  26.795  19.755  1.00 70.58  ? 511 THR E OG1 1 
ATOM   8069  C CG2 . THR E 1 304 ? -69.544  28.624  21.084  1.00 67.24  ? 511 THR E CG2 1 
ATOM   8070  N N   . ASN E 1 305 ? -72.146  29.791  22.612  1.00 69.24  ? 512 ASN E N   1 
ATOM   8071  C CA  . ASN E 1 305 ? -72.565  31.041  23.245  1.00 66.97  ? 512 ASN E CA  1 
ATOM   8072  C C   . ASN E 1 305 ? -72.298  30.975  24.743  1.00 60.56  ? 512 ASN E C   1 
ATOM   8073  O O   . ASN E 1 305 ? -72.047  29.905  25.304  1.00 59.31  ? 512 ASN E O   1 
ATOM   8074  C CB  . ASN E 1 305 ? -74.043  31.311  23.002  1.00 68.50  ? 512 ASN E CB  1 
ATOM   8075  C CG  . ASN E 1 305 ? -74.862  30.049  23.044  1.00 64.45  ? 512 ASN E CG  1 
ATOM   8076  O OD1 . ASN E 1 305 ? -74.787  29.264  24.009  1.00 55.29  ? 512 ASN E OD1 1 
ATOM   8077  N ND2 . ASN E 1 305 ? -75.631  29.823  21.985  1.00 59.98  ? 512 ASN E ND2 1 
ATOM   8078  N N   . ALA E 1 306 ? -72.388  32.146  25.382  1.00 59.54  ? 513 ALA E N   1 
ATOM   8079  C CA  . ALA E 1 306 ? -72.161  32.274  26.820  1.00 60.02  ? 513 ALA E CA  1 
ATOM   8080  C C   . ALA E 1 306 ? -73.300  31.642  27.600  1.00 57.55  ? 513 ALA E C   1 
ATOM   8081  O O   . ALA E 1 306 ? -74.475  31.876  27.293  1.00 52.81  ? 513 ALA E O   1 
ATOM   8082  C CB  . ALA E 1 306 ? -72.037  33.744  27.220  1.00 55.57  ? 513 ALA E CB  1 
ATOM   8083  N N   . TYR E 1 307 ? -72.943  30.838  28.609  1.00 53.62  ? 514 TYR E N   1 
ATOM   8084  C CA  . TYR E 1 307 ? -73.879  30.276  29.574  1.00 50.16  ? 514 TYR E CA  1 
ATOM   8085  C C   . TYR E 1 307 ? -73.822  30.968  30.922  1.00 50.13  ? 514 TYR E C   1 
ATOM   8086  O O   . TYR E 1 307 ? -74.867  31.189  31.540  1.00 53.76  ? 514 TYR E O   1 
ATOM   8087  C CB  . TYR E 1 307 ? -73.595  28.796  29.779  1.00 57.32  ? 514 TYR E CB  1 
ATOM   8088  C CG  . TYR E 1 307 ? -74.514  28.113  30.760  1.00 53.06  ? 514 TYR E CG  1 
ATOM   8089  C CD1 . TYR E 1 307 ? -75.874  28.381  30.770  1.00 51.77  ? 514 TYR E CD1 1 
ATOM   8090  C CD2 . TYR E 1 307 ? -74.022  27.175  31.656  1.00 52.64  ? 514 TYR E CD2 1 
ATOM   8091  C CE1 . TYR E 1 307 ? -76.723  27.738  31.647  1.00 49.69  ? 514 TYR E CE1 1 
ATOM   8092  C CE2 . TYR E 1 307 ? -74.864  26.528  32.547  1.00 55.30  ? 514 TYR E CE2 1 
ATOM   8093  C CZ  . TYR E 1 307 ? -76.216  26.810  32.533  1.00 52.48  ? 514 TYR E CZ  1 
ATOM   8094  O OH  . TYR E 1 307 ? -77.056  26.168  33.415  1.00 52.47  ? 514 TYR E OH  1 
ATOM   8095  N N   . MET E 1 308 ? -72.608  31.275  31.376  1.00 51.25  ? 515 MET E N   1 
ATOM   8096  C CA  . MET E 1 308 ? -72.399  31.939  32.685  1.00 54.52  ? 515 MET E CA  1 
ATOM   8097  C C   . MET E 1 308 ? -71.508  33.167  32.499  1.00 53.19  ? 515 MET E C   1 
ATOM   8098  O O   . MET E 1 308 ? -70.542  33.077  31.741  1.00 54.40  ? 515 MET E O   1 
ATOM   8099  C CB  . MET E 1 308 ? -71.721  30.983  33.669  1.00 56.60  ? 515 MET E CB  1 
ATOM   8100  C CG  . MET E 1 308 ? -72.593  30.497  34.796  1.00 50.86  ? 515 MET E CG  1 
ATOM   8101  S SD  . MET E 1 308 ? -71.573  29.703  36.056  1.00 56.15  ? 515 MET E SD  1 
ATOM   8102  C CE  . MET E 1 308 ? -70.681  31.119  36.692  1.00 55.02  ? 515 MET E CE  1 
ATOM   8103  N N   . LEU E 1 309 ? -71.839  34.256  33.184  1.00 52.32  ? 516 LEU E N   1 
ATOM   8104  C CA  . LEU E 1 309 ? -71.083  35.521  33.050  1.00 50.94  ? 516 LEU E CA  1 
ATOM   8105  C C   . LEU E 1 309 ? -70.639  35.987  34.429  1.00 47.47  ? 516 LEU E C   1 
ATOM   8106  O O   . LEU E 1 309 ? -71.478  36.067  35.325  1.00 50.35  ? 516 LEU E O   1 
ATOM   8107  C CB  . LEU E 1 309 ? -71.992  36.575  32.419  1.00 54.81  ? 516 LEU E CB  1 
ATOM   8108  C CG  . LEU E 1 309 ? -72.450  36.315  30.990  1.00 51.93  ? 516 LEU E CG  1 
ATOM   8109  C CD1 . LEU E 1 309 ? -73.412  37.399  30.551  1.00 51.67  ? 516 LEU E CD1 1 
ATOM   8110  C CD2 . LEU E 1 309 ? -71.260  36.259  30.057  1.00 51.36  ? 516 LEU E CD2 1 
ATOM   8111  N N   . VAL E 1 310 ? -69.356  36.297  34.566  1.00 55.74  ? 517 VAL E N   1 
ATOM   8112  C CA  . VAL E 1 310 ? -68.819  36.803  35.857  1.00 52.85  ? 517 VAL E CA  1 
ATOM   8113  C C   . VAL E 1 310 ? -68.463  38.277  35.685  1.00 55.65  ? 517 VAL E C   1 
ATOM   8114  O O   . VAL E 1 310 ? -67.652  38.586  34.812  1.00 55.56  ? 517 VAL E O   1 
ATOM   8115  C CB  . VAL E 1 310 ? -67.620  35.974  36.345  1.00 50.35  ? 517 VAL E CB  1 
ATOM   8116  C CG1 . VAL E 1 310 ? -67.016  36.531  37.622  1.00 48.02  ? 517 VAL E CG1 1 
ATOM   8117  C CG2 . VAL E 1 310 ? -67.979  34.509  36.507  1.00 49.51  ? 517 VAL E CG2 1 
ATOM   8118  N N   . TYR E 1 311 ? -69.105  39.143  36.460  1.00 53.90  ? 518 TYR E N   1 
ATOM   8119  C CA  . TYR E 1 311 ? -68.808  40.590  36.437  1.00 52.32  ? 518 TYR E CA  1 
ATOM   8120  C C   . TYR E 1 311 ? -68.228  40.953  37.798  1.00 55.30  ? 518 TYR E C   1 
ATOM   8121  O O   . TYR E 1 311 ? -68.646  40.375  38.799  1.00 57.86  ? 518 TYR E O   1 
ATOM   8122  C CB  . TYR E 1 311 ? -70.084  41.388  36.190  1.00 55.29  ? 518 TYR E CB  1 
ATOM   8123  C CG  . TYR E 1 311 ? -70.581  41.402  34.769  1.00 63.80  ? 518 TYR E CG  1 
ATOM   8124  C CD1 . TYR E 1 311 ? -71.239  40.312  34.230  1.00 57.09  ? 518 TYR E CD1 1 
ATOM   8125  C CD2 . TYR E 1 311 ? -70.419  42.520  33.972  1.00 64.73  ? 518 TYR E CD2 1 
ATOM   8126  C CE1 . TYR E 1 311 ? -71.702  40.322  32.927  1.00 56.50  ? 518 TYR E CE1 1 
ATOM   8127  C CE2 . TYR E 1 311 ? -70.873  42.546  32.666  1.00 65.04  ? 518 TYR E CE2 1 
ATOM   8128  C CZ  . TYR E 1 311 ? -71.521  41.444  32.143  1.00 62.39  ? 518 TYR E CZ  1 
ATOM   8129  O OH  . TYR E 1 311 ? -71.978  41.459  30.862  1.00 66.65  ? 518 TYR E OH  1 
ATOM   8130  N N   . ILE E 1 312 ? -67.266  41.866  37.822  1.00 58.48  ? 519 ILE E N   1 
ATOM   8131  C CA  . ILE E 1 312 ? -66.677  42.316  39.114  1.00 51.29  ? 519 ILE E CA  1 
ATOM   8132  C C   . ILE E 1 312 ? -66.991  43.797  39.320  1.00 57.51  ? 519 ILE E C   1 
ATOM   8133  O O   . ILE E 1 312 ? -66.881  44.559  38.364  1.00 63.45  ? 519 ILE E O   1 
ATOM   8134  C CB  . ILE E 1 312 ? -65.169  42.004  39.186  1.00 53.17  ? 519 ILE E CB  1 
ATOM   8135  C CG1 . ILE E 1 312 ? -64.889  40.540  38.845  1.00 51.73  ? 519 ILE E CG1 1 
ATOM   8136  C CG2 . ILE E 1 312 ? -64.597  42.376  40.543  1.00 55.82  ? 519 ILE E CG2 1 
ATOM   8137  C CD1 . ILE E 1 312 ? -63.544  40.057  39.294  1.00 50.91  ? 519 ILE E CD1 1 
ATOM   8138  N N   . ARG E 1 313 ? -67.424  44.171  40.525  1.00 56.24  ? 520 ARG E N   1 
ATOM   8139  C CA  . ARG E 1 313 ? -67.745  45.581  40.855  1.00 53.40  ? 520 ARG E CA  1 
ATOM   8140  C C   . ARG E 1 313 ? -66.479  46.420  40.776  1.00 57.39  ? 520 ARG E C   1 
ATOM   8141  O O   . ARG E 1 313 ? -65.467  46.000  41.329  1.00 58.52  ? 520 ARG E O   1 
ATOM   8142  C CB  . ARG E 1 313 ? -68.329  45.667  42.263  1.00 57.43  ? 520 ARG E CB  1 
ATOM   8143  C CG  . ARG E 1 313 ? -69.278  46.834  42.480  1.00 59.90  ? 520 ARG E CG  1 
ATOM   8144  C CD  . ARG E 1 313 ? -69.869  46.724  43.867  1.00 53.70  ? 520 ARG E CD  1 
ATOM   8145  N NE  . ARG E 1 313 ? -70.691  47.868  44.219  1.00 58.52  ? 520 ARG E NE  1 
ATOM   8146  C CZ  . ARG E 1 313 ? -71.986  47.805  44.486  1.00 58.00  ? 520 ARG E CZ  1 
ATOM   8147  N NH1 . ARG E 1 313 ? -72.619  46.647  44.433  1.00 56.78  ? 520 ARG E NH1 1 
ATOM   8148  N NH2 . ARG E 1 313 ? -72.648  48.900  44.806  1.00 58.80  ? 520 ARG E NH2 1 
ATOM   8149  N N   . GLU E 1 314 ? -66.560  47.581  40.134  1.00 58.95  ? 521 GLU E N   1 
ATOM   8150  C CA  . GLU E 1 314 ? -65.365  48.401  39.946  1.00 57.09  ? 521 GLU E CA  1 
ATOM   8151  C C   . GLU E 1 314 ? -64.784  48.843  41.285  1.00 54.08  ? 521 GLU E C   1 
ATOM   8152  O O   . GLU E 1 314 ? -63.562  48.851  41.466  1.00 57.74  ? 521 GLU E O   1 
ATOM   8153  C CB  . GLU E 1 314 ? -65.671  49.607  39.065  1.00 53.52  ? 521 GLU E CB  1 
ATOM   8154  N N   . SER E 1 315 ? -65.671  49.150  42.226  1.00 53.23  ? 522 SER E N   1 
ATOM   8155  C CA  . SER E 1 315 ? -65.253  49.637  43.561  1.00 51.19  ? 522 SER E CA  1 
ATOM   8156  C C   . SER E 1 315 ? -64.512  48.556  44.336  1.00 59.41  ? 522 SER E C   1 
ATOM   8157  O O   . SER E 1 315 ? -63.804  48.922  45.268  1.00 59.64  ? 522 SER E O   1 
ATOM   8158  C CB  . SER E 1 315 ? -66.451  50.093  44.313  1.00 54.03  ? 522 SER E CB  1 
ATOM   8159  O OG  . SER E 1 315 ? -67.398  49.048  44.441  1.00 64.12  ? 522 SER E OG  1 
ATOM   8160  N N   . LYS E 1 316 ? -64.721  47.289  43.994  1.00 62.02  ? 523 LYS E N   1 
ATOM   8161  C CA  . LYS E 1 316 ? -64.042  46.186  44.649  1.00 64.34  ? 523 LYS E CA  1 
ATOM   8162  C C   . LYS E 1 316 ? -63.013  45.535  43.742  1.00 59.87  ? 523 LYS E C   1 
ATOM   8163  O O   . LYS E 1 316 ? -62.288  44.637  44.188  1.00 63.36  ? 523 LYS E O   1 
ATOM   8164  C CB  . LYS E 1 316 ? -65.067  45.156  45.152  1.00 57.37  ? 523 LYS E CB  1 
ATOM   8165  N N   . LEU E 1 317 ? -62.911  45.994  42.493  1.00 56.07  ? 524 LEU E N   1 
ATOM   8166  C CA  . LEU E 1 317 ? -62.069  45.303  41.524  1.00 62.13  ? 524 LEU E CA  1 
ATOM   8167  C C   . LEU E 1 317 ? -60.618  45.277  41.979  1.00 65.39  ? 524 LEU E C   1 
ATOM   8168  O O   . LEU E 1 317 ? -59.957  44.236  41.918  1.00 67.54  ? 524 LEU E O   1 
ATOM   8169  C CB  . LEU E 1 317 ? -62.192  45.952  40.148  1.00 57.44  ? 524 LEU E CB  1 
ATOM   8170  C CG  . LEU E 1 317 ? -61.413  45.168  39.093  1.00 63.98  ? 524 LEU E CG  1 
ATOM   8171  C CD1 . LEU E 1 317 ? -62.251  44.977  37.828  1.00 66.87  ? 524 LEU E CD1 1 
ATOM   8172  C CD2 . LEU E 1 317 ? -60.097  45.870  38.775  1.00 69.59  ? 524 LEU E CD2 1 
ATOM   8173  N N   . SER E 1 318 ? -60.107  46.419  42.448  1.00 70.13  ? 525 SER E N   1 
ATOM   8174  C CA  . SER E 1 318 ? -58.712  46.477  42.866  1.00 67.12  ? 525 SER E CA  1 
ATOM   8175  C C   . SER E 1 318 ? -58.431  45.466  43.956  1.00 64.26  ? 525 SER E C   1 
ATOM   8176  O O   . SER E 1 318 ? -57.334  44.904  44.013  1.00 66.56  ? 525 SER E O   1 
ATOM   8177  C CB  . SER E 1 318 ? -58.360  47.881  43.353  1.00 72.12  ? 525 SER E CB  1 
ATOM   8178  O OG  . SER E 1 318 ? -58.924  48.114  44.638  1.00 69.63  ? 525 SER E OG  1 
ATOM   8179  N N   . GLU E 1 319 ? -59.414  45.209  44.818  1.00 65.93  ? 526 GLU E N   1 
ATOM   8180  C CA  . GLU E 1 319 ? -59.231  44.294  45.938  1.00 70.16  ? 526 GLU E CA  1 
ATOM   8181  C C   . GLU E 1 319 ? -59.446  42.841  45.528  1.00 71.62  ? 526 GLU E C   1 
ATOM   8182  O O   . GLU E 1 319 ? -58.660  41.960  45.909  1.00 68.73  ? 526 GLU E O   1 
ATOM   8183  C CB  . GLU E 1 319 ? -60.180  44.674  47.073  1.00 61.39  ? 526 GLU E CB  1 
ATOM   8184  C CG  . GLU E 1 319 ? -59.873  44.022  48.402  1.00 69.54  ? 526 GLU E CG  1 
ATOM   8185  C CD  . GLU E 1 319 ? -61.088  43.996  49.313  1.00 74.68  ? 526 GLU E CD  1 
ATOM   8186  O OE1 . GLU E 1 319 ? -61.281  42.992  50.032  1.00 70.30  ? 526 GLU E OE1 1 
ATOM   8187  O OE2 . GLU E 1 319 ? -61.856  44.983  49.299  1.00 83.16  ? 526 GLU E OE2 1 
ATOM   8188  N N   . VAL E 1 320 ? -60.495  42.587  44.744  1.00 62.78  ? 527 VAL E N   1 
ATOM   8189  C CA  . VAL E 1 320 ? -60.782  41.232  44.299  1.00 66.99  ? 527 VAL E CA  1 
ATOM   8190  C C   . VAL E 1 320 ? -59.597  40.667  43.533  1.00 69.87  ? 527 VAL E C   1 
ATOM   8191  O O   . VAL E 1 320 ? -59.215  39.499  43.704  1.00 72.14  ? 527 VAL E O   1 
ATOM   8192  C CB  . VAL E 1 320 ? -62.064  41.226  43.443  1.00 67.26  ? 527 VAL E CB  1 
ATOM   8193  C CG1 . VAL E 1 320 ? -62.231  39.889  42.698  1.00 64.54  ? 527 VAL E CG1 1 
ATOM   8194  C CG2 . VAL E 1 320 ? -63.262  41.502  44.298  1.00 62.03  ? 527 VAL E CG2 1 
ATOM   8195  N N   . LEU E 1 321 ? -58.994  41.491  42.683  1.00 69.27  ? 528 LEU E N   1 
ATOM   8196  C CA  . LEU E 1 321 ? -57.934  41.063  41.789  1.00 67.95  ? 528 LEU E CA  1 
ATOM   8197  C C   . LEU E 1 321 ? -56.548  41.481  42.280  1.00 71.95  ? 528 LEU E C   1 
ATOM   8198  O O   . LEU E 1 321 ? -55.585  41.432  41.506  1.00 70.58  ? 528 LEU E O   1 
ATOM   8199  C CB  . LEU E 1 321 ? -58.214  41.600  40.390  1.00 62.80  ? 528 LEU E CB  1 
ATOM   8200  C CG  . LEU E 1 321 ? -59.566  41.146  39.831  1.00 67.41  ? 528 LEU E CG  1 
ATOM   8201  C CD1 . LEU E 1 321 ? -59.736  41.566  38.370  1.00 65.72  ? 528 LEU E CD1 1 
ATOM   8202  C CD2 . LEU E 1 321 ? -59.764  39.632  39.990  1.00 67.41  ? 528 LEU E CD2 1 
ATOM   8203  N N   . GLN E 1 322 ? -56.434  41.892  43.548  1.00 70.70  ? 529 GLN E N   1 
ATOM   8204  C CA  . GLN E 1 322 ? -55.144  42.062  44.201  1.00 72.38  ? 529 GLN E CA  1 
ATOM   8205  C C   . GLN E 1 322 ? -54.187  40.957  43.776  1.00 77.76  ? 529 GLN E C   1 
ATOM   8206  O O   . GLN E 1 322 ? -54.547  39.778  43.758  1.00 79.36  ? 529 GLN E O   1 
ATOM   8207  C CB  . GLN E 1 322 ? -55.324  42.046  45.722  1.00 71.89  ? 529 GLN E CB  1 
ATOM   8208  N N   . ALA E 1 323 ? -52.977  41.349  43.404  1.00 77.78  ? 530 ALA E N   1 
ATOM   8209  C CA  . ALA E 1 323 ? -52.001  40.390  42.913  1.00 73.18  ? 530 ALA E CA  1 
ATOM   8210  C C   . ALA E 1 323 ? -51.700  39.325  43.960  1.00 73.65  ? 530 ALA E C   1 
ATOM   8211  O O   . ALA E 1 323 ? -51.816  39.550  45.169  1.00 71.99  ? 530 ALA E O   1 
ATOM   8212  C CB  . ALA E 1 323 ? -50.713  41.103  42.512  1.00 77.34  ? 530 ALA E CB  1 
ATOM   8213  N N   . VAL E 1 324 ? -51.364  38.137  43.457  1.00 76.44  ? 531 VAL E N   1 
ATOM   8214  C CA  . VAL E 1 324 ? -51.024  37.007  44.362  1.00 78.07  ? 531 VAL E CA  1 
ATOM   8215  C C   . VAL E 1 324 ? -49.584  36.606  44.082  1.00 78.32  ? 531 VAL E C   1 
ATOM   8216  O O   . VAL E 1 324 ? -49.265  36.330  42.917  1.00 77.04  ? 531 VAL E O   1 
ATOM   8217  C CB  . VAL E 1 324 ? -51.987  35.812  44.229  1.00 78.17  ? 531 VAL E CB  1 
ATOM   8218  C CG1 . VAL E 1 324 ? -51.601  34.668  45.153  1.00 72.80  ? 531 VAL E CG1 1 
ATOM   8219  C CG2 . VAL E 1 324 ? -53.431  36.214  44.472  1.00 69.52  ? 531 VAL E CG2 1 
ATOM   8220  N N   . THR E 1 325 ? -48.761  36.606  45.117  1.00 78.92  ? 532 THR E N   1 
ATOM   8221  C CA  . THR E 1 325 ? -47.329  36.255  45.047  1.00 83.30  ? 532 THR E CA  1 
ATOM   8222  C C   . THR E 1 325 ? -47.090  35.003  45.891  1.00 85.58  ? 532 THR E C   1 
ATOM   8223  O O   . THR E 1 325 ? -48.019  34.582  46.596  1.00 82.11  ? 532 THR E O   1 
ATOM   8224  C CB  . THR E 1 325 ? -46.494  37.401  45.621  1.00 83.98  ? 532 THR E CB  1 
ATOM   8225  O OG1 . THR E 1 325 ? -46.945  37.656  46.951  1.00 79.85  ? 532 THR E OG1 1 
ATOM   8226  C CG2 . THR E 1 325 ? -46.594  38.673  44.809  1.00 79.35  ? 532 THR E CG2 1 
ATOM   8227  N N   . ASP E 1 326 ? -45.877  34.449  45.855  1.00 88.18  ? 533 ASP E N   1 
ATOM   8228  C CA  . ASP E 1 326 ? -45.543  33.288  46.722  1.00 84.96  ? 533 ASP E CA  1 
ATOM   8229  C C   . ASP E 1 326 ? -45.418  33.776  48.166  1.00 86.01  ? 533 ASP E C   1 
ATOM   8230  O O   . ASP E 1 326 ? -45.274  32.926  49.051  1.00 79.38  ? 533 ASP E O   1 
ATOM   8231  C CB  . ASP E 1 326 ? -44.287  32.568  46.238  1.00 83.40  ? 533 ASP E CB  1 
ATOM   8232  C CG  . ASP E 1 326 ? -44.415  31.055  46.225  1.00 97.47  ? 533 ASP E CG  1 
ATOM   8233  O OD1 . ASP E 1 326 ? -44.717  30.480  47.287  1.00 100.92 ? 533 ASP E OD1 1 
ATOM   8234  O OD2 . ASP E 1 326 ? -44.201  30.464  45.153  1.00 104.96 ? 533 ASP E OD2 1 
ATOM   8235  N N   . HIS E 1 327 ? -45.459  35.093  48.391  1.00 89.25  ? 534 HIS E N   1 
ATOM   8236  C CA  . HIS E 1 327 ? -45.454  35.648  49.768  1.00 85.87  ? 534 HIS E CA  1 
ATOM   8237  C C   . HIS E 1 327 ? -46.820  35.404  50.394  1.00 82.21  ? 534 HIS E C   1 
ATOM   8238  O O   . HIS E 1 327 ? -46.905  35.424  51.629  1.00 82.22  ? 534 HIS E O   1 
ATOM   8239  C CB  . HIS E 1 327 ? -45.139  37.142  49.728  1.00 81.12  ? 534 HIS E CB  1 
ATOM   8240  N N   . ASP E 1 328 ? -47.839  35.192  49.560  1.00 84.78  ? 535 ASP E N   1 
ATOM   8241  C CA  . ASP E 1 328 ? -49.215  34.939  50.049  1.00 81.02  ? 535 ASP E CA  1 
ATOM   8242  C C   . ASP E 1 328 ? -49.391  33.438  50.290  1.00 81.30  ? 535 ASP E C   1 
ATOM   8243  O O   . ASP E 1 328 ? -50.267  33.078  51.084  1.00 85.74  ? 535 ASP E O   1 
ATOM   8244  C CB  . ASP E 1 328 ? -50.244  35.516  49.077  1.00 77.07  ? 535 ASP E CB  1 
ATOM   8245  C CG  . ASP E 1 328 ? -50.104  37.010  48.855  1.00 84.23  ? 535 ASP E CG  1 
ATOM   8246  O OD1 . ASP E 1 328 ? -50.173  37.758  49.846  1.00 84.55  ? 535 ASP E OD1 1 
ATOM   8247  O OD2 . ASP E 1 328 ? -49.934  37.411  47.693  1.00 88.49  ? 535 ASP E OD2 1 
ATOM   8248  N N   . ILE E 1 329 ? -48.622  32.622  49.570  1.00 82.17  ? 536 ILE E N   1 
ATOM   8249  C CA  . ILE E 1 329 ? -48.727  31.141  49.685  1.00 80.88  ? 536 ILE E CA  1 
ATOM   8250  C C   . ILE E 1 329 ? -47.810  30.689  50.819  1.00 87.62  ? 536 ILE E C   1 
ATOM   8251  O O   . ILE E 1 329 ? -46.586  30.849  50.696  1.00 86.17  ? 536 ILE E O   1 
ATOM   8252  C CB  . ILE E 1 329 ? -48.373  30.459  48.350  1.00 78.78  ? 536 ILE E CB  1 
ATOM   8253  C CG1 . ILE E 1 329 ? -48.861  31.264  47.144  1.00 77.10  ? 536 ILE E CG1 1 
ATOM   8254  C CG2 . ILE E 1 329 ? -48.890  29.030  48.320  1.00 79.06  ? 536 ILE E CG2 1 
ATOM   8255  C CD1 . ILE E 1 329 ? -48.374  30.735  45.821  1.00 81.99  ? 536 ILE E CD1 1 
ATOM   8256  N N   . PRO E 1 330 ? -48.358  30.125  51.913  1.00 88.46  ? 537 PRO E N   1 
ATOM   8257  C CA  . PRO E 1 330 ? -47.550  29.714  53.056  1.00 89.28  ? 537 PRO E CA  1 
ATOM   8258  C C   . PRO E 1 330 ? -46.496  28.653  52.715  1.00 93.97  ? 537 PRO E C   1 
ATOM   8259  O O   . PRO E 1 330 ? -46.693  27.906  51.786  1.00 93.62  ? 537 PRO E O   1 
ATOM   8260  C CB  . PRO E 1 330 ? -48.594  29.095  53.992  1.00 93.00  ? 537 PRO E CB  1 
ATOM   8261  C CG  . PRO E 1 330 ? -49.886  29.756  53.603  1.00 87.41  ? 537 PRO E CG  1 
ATOM   8262  C CD  . PRO E 1 330 ? -49.784  29.861  52.101  1.00 85.07  ? 537 PRO E CD  1 
ATOM   8263  N N   . GLN E 1 331 ? -45.427  28.584  53.508  1.00 97.32  ? 538 GLN E N   1 
ATOM   8264  C CA  . GLN E 1 331 ? -44.333  27.613  53.245  1.00 93.84  ? 538 GLN E CA  1 
ATOM   8265  C C   . GLN E 1 331 ? -44.781  26.196  53.600  1.00 93.25  ? 538 GLN E C   1 
ATOM   8266  O O   . GLN E 1 331 ? -44.384  25.273  52.878  1.00 89.46  ? 538 GLN E O   1 
ATOM   8267  C CB  . GLN E 1 331 ? -43.095  27.980  54.059  1.00 87.56  ? 538 GLN E CB  1 
ATOM   8268  N N   . GLN E 1 332 ? -45.540  26.035  54.687  1.00 92.27  ? 539 GLN E N   1 
ATOM   8269  C CA  . GLN E 1 332 ? -46.054  24.720  55.045  1.00 87.10  ? 539 GLN E CA  1 
ATOM   8270  C C   . GLN E 1 332 ? -46.723  24.068  53.854  1.00 95.05  ? 539 GLN E C   1 
ATOM   8271  O O   . GLN E 1 332 ? -46.693  22.839  53.717  1.00 97.77  ? 539 GLN E O   1 
ATOM   8272  C CB  . GLN E 1 332 ? -47.039  24.828  56.208  1.00 84.02  ? 539 GLN E CB  1 
ATOM   8273  N N   . LEU E 1 333 ? -47.297  24.886  52.975  1.00 95.22  ? 540 LEU E N   1 
ATOM   8274  C CA  . LEU E 1 333 ? -48.028  24.344  51.804  1.00 89.61  ? 540 LEU E CA  1 
ATOM   8275  C C   . LEU E 1 333 ? -47.022  23.939  50.734  1.00 91.33  ? 540 LEU E C   1 
ATOM   8276  O O   . LEU E 1 333 ? -47.087  22.789  50.283  1.00 96.21  ? 540 LEU E O   1 
ATOM   8277  C CB  . LEU E 1 333 ? -48.973  25.422  51.273  1.00 87.87  ? 540 LEU E CB  1 
ATOM   8278  C CG  . LEU E 1 333 ? -50.439  25.027  51.119  1.00 80.69  ? 540 LEU E CG  1 
ATOM   8279  C CD1 . LEU E 1 333 ? -51.128  25.955  50.136  1.00 83.04  ? 540 LEU E CD1 1 
ATOM   8280  C CD2 . LEU E 1 333 ? -50.583  23.583  50.669  1.00 75.66  ? 540 LEU E CD2 1 
ATOM   8281  N N   . VAL E 1 334 ? -46.140  24.854  50.337  1.00 89.92  ? 541 VAL E N   1 
ATOM   8282  C CA  . VAL E 1 334 ? -45.228  24.523  49.249  1.00 90.77  ? 541 VAL E CA  1 
ATOM   8283  C C   . VAL E 1 334 ? -44.380  23.324  49.616  1.00 91.88  ? 541 VAL E C   1 
ATOM   8284  O O   . VAL E 1 334 ? -43.972  22.549  48.744  1.00 89.49  ? 541 VAL E O   1 
ATOM   8285  C CB  . VAL E 1 334 ? -44.369  25.742  48.888  1.00 89.18  ? 541 VAL E CB  1 
ATOM   8286  C CG1 . VAL E 1 334 ? -43.808  25.579  47.482  1.00 93.45  ? 541 VAL E CG1 1 
ATOM   8287  C CG2 . VAL E 1 334 ? -45.206  26.993  48.999  1.00 87.93  ? 541 VAL E CG2 1 
ATOM   8288  N N   . GLU E 1 335 ? -44.112  23.142  50.907  1.00 97.22  ? 542 GLU E N   1 
ATOM   8289  C CA  . GLU E 1 335 ? -43.453  21.926  51.362  1.00 96.86  ? 542 GLU E CA  1 
ATOM   8290  C C   . GLU E 1 335 ? -44.248  20.694  50.946  1.00 93.16  ? 542 GLU E C   1 
ATOM   8291  O O   . GLU E 1 335 ? -43.764  19.859  50.175  1.00 96.79  ? 542 GLU E O   1 
ATOM   8292  C CB  . GLU E 1 335 ? -43.262  21.975  52.881  1.00 97.21  ? 542 GLU E CB  1 
ATOM   8293  N N   . ARG E 1 336 ? -45.487  20.574  51.437  1.00 94.59  ? 543 ARG E N   1 
ATOM   8294  C CA  . ARG E 1 336 ? -46.278  19.374  51.173  1.00 98.00  ? 543 ARG E CA  1 
ATOM   8295  C C   . ARG E 1 336 ? -46.449  19.125  49.676  1.00 95.32  ? 543 ARG E C   1 
ATOM   8296  O O   . ARG E 1 336 ? -46.564  17.967  49.250  1.00 87.58  ? 543 ARG E O   1 
ATOM   8297  C CB  . ARG E 1 336 ? -47.641  19.476  51.868  1.00 86.78  ? 543 ARG E CB  1 
ATOM   8298  N N   . LEU E 1 337 ? -46.434  20.189  48.860  1.00 91.03  ? 544 LEU E N   1 
ATOM   8299  C CA  . LEU E 1 337 ? -46.591  20.024  47.416  1.00 92.21  ? 544 LEU E CA  1 
ATOM   8300  C C   . LEU E 1 337 ? -45.297  19.582  46.740  1.00 97.55  ? 544 LEU E C   1 
ATOM   8301  O O   . LEU E 1 337 ? -45.342  18.927  45.692  1.00 102.56 ? 544 LEU E O   1 
ATOM   8302  C CB  . LEU E 1 337 ? -47.100  21.322  46.783  1.00 90.90  ? 544 LEU E CB  1 
ATOM   8303  C CG  . LEU E 1 337 ? -48.487  21.811  47.221  1.00 86.25  ? 544 LEU E CG  1 
ATOM   8304  C CD1 . LEU E 1 337 ? -48.794  23.190  46.676  1.00 89.03  ? 544 LEU E CD1 1 
ATOM   8305  C CD2 . LEU E 1 337 ? -49.550  20.858  46.760  1.00 83.70  ? 544 LEU E CD2 1 
ATOM   8306  N N   . GLN E 1 338 ? -44.141  19.928  47.314  1.00 101.37 ? 545 GLN E N   1 
ATOM   8307  C CA  . GLN E 1 338 ? -42.882  19.373  46.831  1.00 97.21  ? 545 GLN E CA  1 
ATOM   8308  C C   . GLN E 1 338 ? -42.728  17.902  47.201  1.00 95.28  ? 545 GLN E C   1 
ATOM   8309  O O   . GLN E 1 338 ? -41.986  17.185  46.520  1.00 104.27 ? 545 GLN E O   1 
ATOM   8310  C CB  . GLN E 1 338 ? -41.696  20.178  47.377  1.00 91.95  ? 545 GLN E CB  1 
ATOM   8311  N N   . GLU E 1 339 ? -43.429  17.436  48.245  1.00 93.78  ? 546 GLU E N   1 
ATOM   8312  C CA  . GLU E 1 339 ? -43.292  16.059  48.721  1.00 95.08  ? 546 GLU E CA  1 
ATOM   8313  C C   . GLU E 1 339 ? -43.648  15.027  47.658  1.00 95.38  ? 546 GLU E C   1 
ATOM   8314  O O   . GLU E 1 339 ? -43.232  13.868  47.775  1.00 89.56  ? 546 GLU E O   1 
ATOM   8315  C CB  . GLU E 1 339 ? -44.164  15.843  49.959  1.00 90.10  ? 546 GLU E CB  1 
ATOM   8316  N N   . GLU E 1 340 ? -44.402  15.419  46.635  1.00 97.71  ? 547 GLU E N   1 
ATOM   8317  C CA  . GLU E 1 340 ? -44.739  14.549  45.512  1.00 97.42  ? 547 GLU E CA  1 
ATOM   8318  C C   . GLU E 1 340 ? -43.502  13.938  44.842  1.00 96.80  ? 547 GLU E C   1 
ATOM   8319  O O   . GLU E 1 340 ? -42.886  14.548  43.968  1.00 91.58  ? 547 GLU E O   1 
ATOM   8320  C CB  . GLU E 1 340 ? -45.554  15.334  44.484  1.00 91.05  ? 547 GLU E CB  1 
ATOM   8321  N N   . MET F 2 1   ? -97.796  24.540  53.563  1.00 58.86  ? 1   MET F N   1 
ATOM   8322  C CA  . MET F 2 1   ? -97.456  25.913  53.209  1.00 55.00  ? 1   MET F CA  1 
ATOM   8323  C C   . MET F 2 1   ? -97.235  26.126  51.728  1.00 55.38  ? 1   MET F C   1 
ATOM   8324  O O   . MET F 2 1   ? -96.993  25.191  50.969  1.00 58.33  ? 1   MET F O   1 
ATOM   8325  C CB  . MET F 2 1   ? -96.203  26.335  53.947  1.00 53.17  ? 1   MET F CB  1 
ATOM   8326  C CG  . MET F 2 1   ? -95.005  25.641  53.445  1.00 52.99  ? 1   MET F CG  1 
ATOM   8327  S SD  . MET F 2 1   ? -93.716  25.608  54.666  1.00 55.96  ? 1   MET F SD  1 
ATOM   8328  C CE  . MET F 2 1   ? -92.568  24.546  53.829  1.00 52.95  ? 1   MET F CE  1 
ATOM   8329  N N   . GLN F 2 2   ? -97.332  27.406  51.357  1.00 56.18  ? 2   GLN F N   1 
ATOM   8330  C CA  . GLN F 2 2   ? -97.186  27.809  49.945  1.00 47.50  ? 2   GLN F CA  1 
ATOM   8331  C C   . GLN F 2 2   ? -95.845  28.495  49.746  1.00 46.72  ? 2   GLN F C   1 
ATOM   8332  O O   . GLN F 2 2   ? -95.592  29.510  50.395  1.00 53.20  ? 2   GLN F O   1 
ATOM   8333  C CB  . GLN F 2 2   ? -98.305  28.770  49.563  1.00 48.96  ? 2   GLN F CB  1 
ATOM   8334  C CG  . GLN F 2 2   ? -98.397  29.071  48.079  1.00 51.10  ? 2   GLN F CG  1 
ATOM   8335  C CD  . GLN F 2 2   ? -99.254  30.287  47.841  1.00 52.92  ? 2   GLN F CD  1 
ATOM   8336  O OE1 . GLN F 2 2   ? -98.916  31.394  48.244  1.00 54.48  ? 2   GLN F OE1 1 
ATOM   8337  N NE2 . GLN F 2 2   ? -100.387 30.083  47.193  1.00 56.69  ? 2   GLN F NE2 1 
ATOM   8338  N N   . ILE F 2 3   ? -95.034  27.937  48.863  1.00 49.18  ? 3   ILE F N   1 
ATOM   8339  C CA  . ILE F 2 3   ? -93.727  28.546  48.524  1.00 46.60  ? 3   ILE F CA  1 
ATOM   8340  C C   . ILE F 2 3   ? -93.820  29.059  47.095  1.00 49.97  ? 3   ILE F C   1 
ATOM   8341  O O   . ILE F 2 3   ? -94.874  28.907  46.466  1.00 50.90  ? 3   ILE F O   1 
ATOM   8342  C CB  . ILE F 2 3   ? -92.613  27.496  48.656  1.00 46.61  ? 3   ILE F CB  1 
ATOM   8343  C CG1 . ILE F 2 3   ? -92.770  26.368  47.634  1.00 45.60  ? 3   ILE F CG1 1 
ATOM   8344  C CG2 . ILE F 2 3   ? -92.545  26.950  50.069  1.00 53.04  ? 3   ILE F CG2 1 
ATOM   8345  C CD1 . ILE F 2 3   ? -91.695  25.319  47.708  1.00 40.83  ? 3   ILE F CD1 1 
ATOM   8346  N N   . PHE F 2 4   ? -92.732  29.654  46.637  1.00 48.74  ? 4   PHE F N   1 
ATOM   8347  C CA  . PHE F 2 4   ? -92.693  30.160  45.257  1.00 44.07  ? 4   PHE F CA  1 
ATOM   8348  C C   . PHE F 2 4   ? -91.564  29.476  44.512  1.00 44.56  ? 4   PHE F C   1 
ATOM   8349  O O   . PHE F 2 4   ? -90.515  29.291  45.088  1.00 46.04  ? 4   PHE F O   1 
ATOM   8350  C CB  . PHE F 2 4   ? -92.478  31.670  45.255  1.00 45.50  ? 4   PHE F CB  1 
ATOM   8351  C CG  . PHE F 2 4   ? -93.592  32.481  45.860  1.00 49.47  ? 4   PHE F CG  1 
ATOM   8352  C CD1 . PHE F 2 4   ? -94.887  32.372  45.387  1.00 48.24  ? 4   PHE F CD1 1 
ATOM   8353  C CD2 . PHE F 2 4   ? -93.338  33.361  46.896  1.00 50.75  ? 4   PHE F CD2 1 
ATOM   8354  C CE1 . PHE F 2 4   ? -95.908  33.122  45.945  1.00 47.96  ? 4   PHE F CE1 1 
ATOM   8355  C CE2 . PHE F 2 4   ? -94.360  34.112  47.450  1.00 48.92  ? 4   PHE F CE2 1 
ATOM   8356  C CZ  . PHE F 2 4   ? -95.642  33.991  46.974  1.00 50.24  ? 4   PHE F CZ  1 
ATOM   8357  N N   . VAL F 2 5   ? -91.841  28.975  43.326  1.00 43.31  ? 5   VAL F N   1 
ATOM   8358  C CA  . VAL F 2 5   ? -90.806  28.461  42.444  1.00 44.91  ? 5   VAL F CA  1 
ATOM   8359  C C   . VAL F 2 5   ? -90.732  29.420  41.282  1.00 46.40  ? 5   VAL F C   1 
ATOM   8360  O O   . VAL F 2 5   ? -91.765  29.799  40.719  1.00 48.38  ? 5   VAL F O   1 
ATOM   8361  C CB  . VAL F 2 5   ? -91.110  27.031  41.962  1.00 44.73  ? 5   VAL F CB  1 
ATOM   8362  C CG1 . VAL F 2 5   ? -90.026  26.535  41.030  1.00 38.01  ? 5   VAL F CG1 1 
ATOM   8363  C CG2 . VAL F 2 5   ? -91.313  26.085  43.153  1.00 41.96  ? 5   VAL F CG2 1 
ATOM   8364  N N   . LYS F 2 6   ? -89.532  29.839  40.949  1.00 49.27  ? 6   LYS F N   1 
ATOM   8365  C CA  . LYS F 2 6   ? -89.303  30.688  39.794  1.00 48.41  ? 6   LYS F CA  1 
ATOM   8366  C C   . LYS F 2 6   ? -88.899  29.757  38.662  1.00 49.03  ? 6   LYS F C   1 
ATOM   8367  O O   . LYS F 2 6   ? -87.861  29.094  38.754  1.00 58.05  ? 6   LYS F O   1 
ATOM   8368  C CB  . LYS F 2 6   ? -88.240  31.746  40.103  1.00 47.69  ? 6   LYS F CB  1 
ATOM   8369  C CG  . LYS F 2 6   ? -88.853  33.164  40.336  1.00 56.51  ? 6   LYS F CG  1 
ATOM   8370  C CD  . LYS F 2 6   ? -87.853  34.324  40.222  1.00 62.98  ? 6   LYS F CD  1 
ATOM   8371  C CE  . LYS F 2 6   ? -88.460  35.492  39.422  1.00 68.00  ? 6   LYS F CE  1 
ATOM   8372  N NZ  . LYS F 2 6   ? -87.611  36.733  39.383  1.00 66.19  ? 6   LYS F NZ  1 
ATOM   8373  N N   . THR F 2 7   ? -89.726  29.676  37.616  1.00 45.72  ? 7   THR F N   1 
ATOM   8374  C CA  . THR F 2 7   ? -89.569  28.651  36.587  1.00 49.22  ? 7   THR F CA  1 
ATOM   8375  C C   . THR F 2 7   ? -88.682  29.136  35.442  1.00 54.59  ? 7   THR F C   1 
ATOM   8376  O O   . THR F 2 7   ? -88.140  30.240  35.461  1.00 55.08  ? 7   THR F O   1 
ATOM   8377  C CB  . THR F 2 7   ? -90.911  28.235  36.013  1.00 47.86  ? 7   THR F CB  1 
ATOM   8378  O OG1 . THR F 2 7   ? -91.414  29.335  35.264  1.00 59.23  ? 7   THR F OG1 1 
ATOM   8379  C CG2 . THR F 2 7   ? -91.892  27.908  37.104  1.00 49.66  ? 7   THR F CG2 1 
ATOM   8380  N N   . LEU F 2 8   ? -88.553  28.309  34.404  1.00 58.14  ? 8   LEU F N   1 
ATOM   8381  C CA  . LEU F 2 8   ? -87.606  28.601  33.334  1.00 59.22  ? 8   LEU F CA  1 
ATOM   8382  C C   . LEU F 2 8   ? -88.038  29.800  32.509  1.00 57.31  ? 8   LEU F C   1 
ATOM   8383  O O   . LEU F 2 8   ? -87.190  30.524  31.979  1.00 56.52  ? 8   LEU F O   1 
ATOM   8384  C CB  . LEU F 2 8   ? -87.445  27.375  32.443  1.00 57.58  ? 8   LEU F CB  1 
ATOM   8385  C CG  . LEU F 2 8   ? -87.096  26.130  33.250  1.00 59.86  ? 8   LEU F CG  1 
ATOM   8386  C CD1 . LEU F 2 8   ? -86.873  24.926  32.331  1.00 60.37  ? 8   LEU F CD1 1 
ATOM   8387  C CD2 . LEU F 2 8   ? -85.864  26.405  34.104  1.00 58.74  ? 8   LEU F CD2 1 
ATOM   8388  N N   . THR F 2 9   ? -89.341  30.032  32.386  1.00 61.28  ? 9   THR F N   1 
ATOM   8389  C CA  . THR F 2 9   ? -89.782  31.238  31.693  1.00 60.39  ? 9   THR F CA  1 
ATOM   8390  C C   . THR F 2 9   ? -89.488  32.499  32.475  1.00 53.81  ? 9   THR F C   1 
ATOM   8391  O O   . THR F 2 9   ? -89.771  33.586  31.972  1.00 58.60  ? 9   THR F O   1 
ATOM   8392  C CB  . THR F 2 9   ? -91.280  31.189  31.411  1.00 58.50  ? 9   THR F CB  1 
ATOM   8393  O OG1 . THR F 2 9   ? -91.994  31.500  32.620  1.00 59.85  ? 9   THR F OG1 1 
ATOM   8394  C CG2 . THR F 2 9   ? -91.688  29.793  30.933  1.00 61.61  ? 9   THR F CG2 1 
ATOM   8395  N N   . GLY F 2 10  ? -88.903  32.383  33.656  1.00 54.14  ? 10  GLY F N   1 
ATOM   8396  C CA  . GLY F 2 10  ? -88.689  33.522  34.509  1.00 50.94  ? 10  GLY F CA  1 
ATOM   8397  C C   . GLY F 2 10  ? -89.848  33.842  35.419  1.00 48.80  ? 10  GLY F C   1 
ATOM   8398  O O   . GLY F 2 10  ? -89.659  34.583  36.380  1.00 53.13  ? 10  GLY F O   1 
ATOM   8399  N N   . LYS F 2 11  ? -91.033  33.290  35.153  1.00 57.73  ? 11  LYS F N   1 
ATOM   8400  C CA  . LYS F 2 11  ? -92.254  33.594  35.886  1.00 53.44  ? 11  LYS F CA  1 
ATOM   8401  C C   . LYS F 2 11  ? -92.377  32.704  37.118  1.00 54.22  ? 11  LYS F C   1 
ATOM   8402  O O   . LYS F 2 11  ? -91.791  31.622  37.199  1.00 59.60  ? 11  LYS F O   1 
ATOM   8403  C CB  . LYS F 2 11  ? -93.468  33.416  34.984  1.00 50.71  ? 11  LYS F CB  1 
ATOM   8404  N N   . THR F 2 12  ? -93.153  33.178  38.080  1.00 55.24  ? 12  THR F N   1 
ATOM   8405  C CA  . THR F 2 12  ? -93.232  32.604  39.421  1.00 51.13  ? 12  THR F CA  1 
ATOM   8406  C C   . THR F 2 12  ? -94.527  31.816  39.568  1.00 49.16  ? 12  THR F C   1 
ATOM   8407  O O   . THR F 2 12  ? -95.618  32.382  39.432  1.00 52.25  ? 12  THR F O   1 
ATOM   8408  C CB  . THR F 2 12  ? -93.199  33.715  40.473  1.00 49.13  ? 12  THR F CB  1 
ATOM   8409  O OG1 . THR F 2 12  ? -91.923  34.362  40.477  1.00 56.42  ? 12  THR F OG1 1 
ATOM   8410  C CG2 . THR F 2 12  ? -93.468  33.152  41.821  1.00 51.70  ? 12  THR F CG2 1 
ATOM   8411  N N   . ILE F 2 13  ? -94.421  30.534  39.886  1.00 45.98  ? 13  ILE F N   1 
ATOM   8412  C CA  . ILE F 2 13  ? -95.603  29.748  40.207  1.00 47.21  ? 13  ILE F CA  1 
ATOM   8413  C C   . ILE F 2 13  ? -95.605  29.474  41.695  1.00 45.12  ? 13  ILE F C   1 
ATOM   8414  O O   . ILE F 2 13  ? -94.580  29.568  42.374  1.00 49.47  ? 13  ILE F O   1 
ATOM   8415  C CB  . ILE F 2 13  ? -95.692  28.423  39.434  1.00 49.92  ? 13  ILE F CB  1 
ATOM   8416  C CG1 . ILE F 2 13  ? -94.572  27.483  39.902  1.00 47.49  ? 13  ILE F CG1 1 
ATOM   8417  C CG2 . ILE F 2 13  ? -95.681  28.676  37.916  1.00 44.17  ? 13  ILE F CG2 1 
ATOM   8418  C CD1 . ILE F 2 13  ? -94.585  26.138  39.258  1.00 45.51  ? 13  ILE F CD1 1 
ATOM   8419  N N   . THR F 2 14  ? -96.772  29.105  42.202  1.00 43.13  ? 14  THR F N   1 
ATOM   8420  C CA  . THR F 2 14  ? -96.894  28.709  43.593  1.00 43.88  ? 14  THR F CA  1 
ATOM   8421  C C   . THR F 2 14  ? -96.890  27.186  43.721  1.00 44.96  ? 14  THR F C   1 
ATOM   8422  O O   . THR F 2 14  ? -97.335  26.477  42.821  1.00 47.45  ? 14  THR F O   1 
ATOM   8423  C CB  . THR F 2 14  ? -98.166  29.309  44.192  1.00 46.45  ? 14  THR F CB  1 
ATOM   8424  O OG1 . THR F 2 14  ? -99.308  28.685  43.614  1.00 51.01  ? 14  THR F OG1 1 
ATOM   8425  C CG2 . THR F 2 14  ? -98.240  30.789  43.897  1.00 51.15  ? 14  THR F CG2 1 
ATOM   8426  N N   . LEU F 2 15  ? -96.436  26.709  44.881  1.00 44.61  ? 15  LEU F N   1 
ATOM   8427  C CA  . LEU F 2 15  ? -96.426  25.254  45.178  1.00 44.43  ? 15  LEU F CA  1 
ATOM   8428  C C   . LEU F 2 15  ? -96.879  25.020  46.622  1.00 47.89  ? 15  LEU F C   1 
ATOM   8429  O O   . LEU F 2 15  ? -96.386  25.722  47.500  1.00 50.14  ? 15  LEU F O   1 
ATOM   8430  C CB  . LEU F 2 15  ? -95.009  24.718  44.959  1.00 42.83  ? 15  LEU F CB  1 
ATOM   8431  C CG  . LEU F 2 15  ? -94.891  23.412  44.179  1.00 50.48  ? 15  LEU F CG  1 
ATOM   8432  C CD1 . LEU F 2 15  ? -95.058  23.653  42.689  1.00 41.92  ? 15  LEU F CD1 1 
ATOM   8433  C CD2 . LEU F 2 15  ? -93.554  22.752  44.453  1.00 44.41  ? 15  LEU F CD2 1 
ATOM   8434  N N   . GLU F 2 16  ? -97.796  24.079  46.853  1.00 51.79  ? 16  GLU F N   1 
ATOM   8435  C CA  . GLU F 2 16  ? -98.226  23.706  48.199  1.00 53.54  ? 16  GLU F CA  1 
ATOM   8436  C C   . GLU F 2 16  ? -97.380  22.521  48.648  1.00 53.03  ? 16  GLU F C   1 
ATOM   8437  O O   . GLU F 2 16  ? -97.449  21.438  48.056  1.00 47.97  ? 16  GLU F O   1 
ATOM   8438  C CB  . GLU F 2 16  ? -99.716  23.374  48.248  1.00 46.41  ? 16  GLU F CB  1 
ATOM   8439  C CG  . GLU F 2 16  ? -100.557 24.444  48.906  1.00 52.90  ? 16  GLU F CG  1 
ATOM   8440  C CD  . GLU F 2 16  ? -100.426 24.428  50.423  1.00 63.87  ? 16  GLU F CD  1 
ATOM   8441  O OE1 . GLU F 2 16  ? -100.942 25.367  51.081  1.00 62.06  ? 16  GLU F OE1 1 
ATOM   8442  O OE2 . GLU F 2 16  ? -99.810  23.471  50.959  1.00 63.41  ? 16  GLU F OE2 1 
ATOM   8443  N N   . VAL F 2 17  ? -96.578  22.727  49.685  1.00 54.70  ? 17  VAL F N   1 
ATOM   8444  C CA  . VAL F 2 17  ? -95.696  21.679  50.174  1.00 56.69  ? 17  VAL F CA  1 
ATOM   8445  C C   . VAL F 2 17  ? -95.751  21.615  51.689  1.00 57.43  ? 17  VAL F C   1 
ATOM   8446  O O   . VAL F 2 17  ? -96.028  22.610  52.366  1.00 59.68  ? 17  VAL F O   1 
ATOM   8447  C CB  . VAL F 2 17  ? -94.252  21.898  49.718  1.00 49.88  ? 17  VAL F CB  1 
ATOM   8448  C CG1 . VAL F 2 17  ? -94.186  21.886  48.208  1.00 51.11  ? 17  VAL F CG1 1 
ATOM   8449  C CG2 . VAL F 2 17  ? -93.744  23.198  50.282  1.00 53.11  ? 17  VAL F CG2 1 
ATOM   8450  N N   . GLU F 2 18  ? -95.471  20.409  52.227  1.00 54.56  ? 18  GLU F N   1 
ATOM   8451  C CA  . GLU F 2 18  ? -95.258  20.407  53.660  1.00 58.05  ? 18  GLU F CA  1 
ATOM   8452  C C   . GLU F 2 18  ? -93.770  20.536  53.974  1.00 56.31  ? 18  GLU F C   1 
ATOM   8453  O O   . GLU F 2 18  ? -92.921  20.113  53.173  1.00 54.20  ? 18  GLU F O   1 
ATOM   8454  C CB  . GLU F 2 18  ? -95.812  19.125  54.273  1.00 57.09  ? 18  GLU F CB  1 
ATOM   8455  C CG  . GLU F 2 18  ? -97.307  19.171  54.522  1.00 60.29  ? 18  GLU F CG  1 
ATOM   8456  C CD  . GLU F 2 18  ? -97.699  20.199  55.574  1.00 65.70  ? 18  GLU F CD  1 
ATOM   8457  O OE1 . GLU F 2 18  ? -97.707  21.419  55.278  1.00 63.38  ? 18  GLU F OE1 1 
ATOM   8458  O OE2 . GLU F 2 18  ? -98.013  19.776  56.708  1.00 80.14  ? 18  GLU F OE2 1 
ATOM   8459  N N   . PRO F 2 19  ? -93.435  21.133  55.125  1.00 50.74  ? 19  PRO F N   1 
ATOM   8460  C CA  . PRO F 2 19  ? -92.025  21.146  55.575  1.00 45.56  ? 19  PRO F CA  1 
ATOM   8461  C C   . PRO F 2 19  ? -91.409  19.762  55.705  1.00 51.57  ? 19  PRO F C   1 
ATOM   8462  O O   . PRO F 2 19  ? -90.184  19.634  55.717  1.00 56.42  ? 19  PRO F O   1 
ATOM   8463  C CB  . PRO F 2 19  ? -92.094  21.847  56.933  1.00 46.82  ? 19  PRO F CB  1 
ATOM   8464  C CG  . PRO F 2 19  ? -93.368  22.632  56.908  1.00 48.28  ? 19  PRO F CG  1 
ATOM   8465  C CD  . PRO F 2 19  ? -94.324  21.909  56.004  1.00 51.81  ? 19  PRO F CD  1 
ATOM   8466  N N   . SER F 2 20  ? -92.223  18.718  55.812  1.00 58.53  ? 20  SER F N   1 
ATOM   8467  C CA  . SER F 2 20  ? -91.774  17.334  55.795  1.00 53.56  ? 20  SER F CA  1 
ATOM   8468  C C   . SER F 2 20  ? -91.332  16.866  54.414  1.00 49.78  ? 20  SER F C   1 
ATOM   8469  O O   . SER F 2 20  ? -90.803  15.758  54.300  1.00 54.14  ? 20  SER F O   1 
ATOM   8470  C CB  . SER F 2 20  ? -92.920  16.417  56.251  1.00 57.63  ? 20  SER F CB  1 
ATOM   8471  O OG  . SER F 2 20  ? -93.723  17.008  57.267  1.00 63.61  ? 20  SER F OG  1 
ATOM   8472  N N   . ASP F 2 21  ? -91.578  17.635  53.364  1.00 45.56  ? 21  ASP F N   1 
ATOM   8473  C CA  . ASP F 2 21  ? -91.472  17.091  52.013  1.00 57.00  ? 21  ASP F CA  1 
ATOM   8474  C C   . ASP F 2 21  ? -90.017  16.982  51.566  1.00 52.62  ? 21  ASP F C   1 
ATOM   8475  O O   . ASP F 2 21  ? -89.237  17.935  51.682  1.00 53.72  ? 21  ASP F O   1 
ATOM   8476  C CB  . ASP F 2 21  ? -92.258  17.944  51.005  1.00 55.97  ? 21  ASP F CB  1 
ATOM   8477  C CG  . ASP F 2 21  ? -93.735  17.600  50.964  1.00 57.74  ? 21  ASP F CG  1 
ATOM   8478  O OD1 . ASP F 2 21  ? -94.088  16.423  51.221  1.00 56.79  ? 21  ASP F OD1 1 
ATOM   8479  O OD2 . ASP F 2 21  ? -94.544  18.502  50.667  1.00 56.46  ? 21  ASP F OD2 1 
ATOM   8480  N N   . THR F 2 22  ? -89.662  15.835  51.016  1.00 48.47  ? 22  THR F N   1 
ATOM   8481  C CA  . THR F 2 22  ? -88.313  15.711  50.501  1.00 55.29  ? 22  THR F CA  1 
ATOM   8482  C C   . THR F 2 22  ? -88.167  16.455  49.167  1.00 51.35  ? 22  THR F C   1 
ATOM   8483  O O   . THR F 2 22  ? -89.140  16.851  48.520  1.00 46.50  ? 22  THR F O   1 
ATOM   8484  C CB  . THR F 2 22  ? -87.936  14.232  50.357  1.00 59.33  ? 22  THR F CB  1 
ATOM   8485  O OG1 . THR F 2 22  ? -88.897  13.555  49.531  1.00 56.44  ? 22  THR F OG1 1 
ATOM   8486  C CG2 . THR F 2 22  ? -87.889  13.557  51.740  1.00 54.43  ? 22  THR F CG2 1 
ATOM   8487  N N   . ILE F 2 23  ? -86.912  16.645  48.759  1.00 53.03  ? 23  ILE F N   1 
ATOM   8488  C CA  . ILE F 2 23  ? -86.628  17.389  47.535  1.00 51.45  ? 23  ILE F CA  1 
ATOM   8489  C C   . ILE F 2 23  ? -87.257  16.699  46.334  1.00 50.02  ? 23  ILE F C   1 
ATOM   8490  O O   . ILE F 2 23  ? -87.808  17.351  45.436  1.00 47.23  ? 23  ILE F O   1 
ATOM   8491  C CB  . ILE F 2 23  ? -85.107  17.579  47.373  1.00 48.59  ? 23  ILE F CB  1 
ATOM   8492  C CG1 . ILE F 2 23  ? -84.575  18.450  48.503  1.00 53.90  ? 23  ILE F CG1 1 
ATOM   8493  C CG2 . ILE F 2 23  ? -84.764  18.261  46.087  1.00 46.98  ? 23  ILE F CG2 1 
ATOM   8494  C CD1 . ILE F 2 23  ? -85.518  19.557  48.933  1.00 51.59  ? 23  ILE F CD1 1 
ATOM   8495  N N   . GLU F 2 24  ? -87.209  15.371  46.300  1.00 52.03  ? 24  GLU F N   1 
ATOM   8496  C CA  . GLU F 2 24  ? -87.851  14.700  45.181  1.00 49.49  ? 24  GLU F CA  1 
ATOM   8497  C C   . GLU F 2 24  ? -89.360  14.794  45.307  1.00 48.21  ? 24  GLU F C   1 
ATOM   8498  O O   . GLU F 2 24  ? -90.056  14.863  44.286  1.00 43.99  ? 24  GLU F O   1 
ATOM   8499  C CB  . GLU F 2 24  ? -87.375  13.251  45.064  1.00 43.78  ? 24  GLU F CB  1 
ATOM   8500  C CG  . GLU F 2 24  ? -87.273  12.518  46.359  1.00 52.43  ? 24  GLU F CG  1 
ATOM   8501  C CD  . GLU F 2 24  ? -85.863  12.500  46.920  1.00 56.33  ? 24  GLU F CD  1 
ATOM   8502  O OE1 . GLU F 2 24  ? -85.517  13.446  47.660  1.00 57.25  ? 24  GLU F OE1 1 
ATOM   8503  O OE2 . GLU F 2 24  ? -85.113  11.537  46.641  1.00 55.73  ? 24  GLU F OE2 1 
ATOM   8504  N N   . ASN F 2 25  ? -89.875  14.846  46.542  1.00 47.75  ? 25  ASN F N   1 
ATOM   8505  C CA  . ASN F 2 25  ? -91.293  15.140  46.731  1.00 48.57  ? 25  ASN F CA  1 
ATOM   8506  C C   . ASN F 2 25  ? -91.635  16.472  46.099  1.00 48.63  ? 25  ASN F C   1 
ATOM   8507  O O   . ASN F 2 25  ? -92.644  16.592  45.393  1.00 54.95  ? 25  ASN F O   1 
ATOM   8508  C CB  . ASN F 2 25  ? -91.672  15.177  48.215  1.00 54.94  ? 25  ASN F CB  1 
ATOM   8509  C CG  . ASN F 2 25  ? -92.006  13.812  48.796  1.00 53.64  ? 25  ASN F CG  1 
ATOM   8510  O OD1 . ASN F 2 25  ? -92.269  12.837  48.075  1.00 47.85  ? 25  ASN F OD1 1 
ATOM   8511  N ND2 . ASN F 2 25  ? -91.991  13.740  50.128  1.00 53.40  ? 25  ASN F ND2 1 
ATOM   8512  N N   . VAL F 2 26  ? -90.817  17.487  46.352  1.00 40.48  ? 26  VAL F N   1 
ATOM   8513  C CA  . VAL F 2 26  ? -91.061  18.848  45.794  1.00 40.56  ? 26  VAL F CA  1 
ATOM   8514  C C   . VAL F 2 26  ? -90.831  18.812  44.286  1.00 43.87  ? 26  VAL F C   1 
ATOM   8515  O O   . VAL F 2 26  ? -91.618  19.431  43.569  1.00 47.97  ? 26  VAL F O   1 
ATOM   8516  C CB  . VAL F 2 26  ? -90.191  19.891  46.518  1.00 48.25  ? 26  VAL F CB  1 
ATOM   8517  C CG1 . VAL F 2 26  ? -90.204  21.254  45.848  1.00 40.84  ? 26  VAL F CG1 1 
ATOM   8518  C CG2 . VAL F 2 26  ? -90.616  20.013  47.967  1.00 43.00  ? 26  VAL F CG2 1 
ATOM   8519  N N   . LYS F 2 27  ? -89.821  18.074  43.826  1.00 40.71  ? 27  LYS F N   1 
ATOM   8520  C CA  . LYS F 2 27  ? -89.652  17.941  42.388  1.00 41.61  ? 27  LYS F CA  1 
ATOM   8521  C C   . LYS F 2 27  ? -90.840  17.234  41.758  1.00 45.31  ? 27  LYS F C   1 
ATOM   8522  O O   . LYS F 2 27  ? -91.113  17.417  40.562  1.00 46.02  ? 27  LYS F O   1 
ATOM   8523  C CB  . LYS F 2 27  ? -88.377  17.170  42.057  1.00 48.45  ? 27  LYS F CB  1 
ATOM   8524  C CG  . LYS F 2 27  ? -87.050  17.836  42.384  1.00 49.47  ? 27  LYS F CG  1 
ATOM   8525  C CD  . LYS F 2 27  ? -85.932  17.078  41.653  1.00 53.99  ? 27  LYS F CD  1 
ATOM   8526  C CE  . LYS F 2 27  ? -84.525  17.494  42.104  1.00 57.04  ? 27  LYS F CE  1 
ATOM   8527  N NZ  . LYS F 2 27  ? -83.480  16.717  41.380  1.00 56.70  ? 27  LYS F NZ  1 
ATOM   8528  N N   . ALA F 2 28  ? -91.530  16.385  42.527  1.00 49.01  ? 28  ALA F N   1 
ATOM   8529  C CA  . ALA F 2 28  ? -92.667  15.657  41.967  1.00 48.84  ? 28  ALA F CA  1 
ATOM   8530  C C   . ALA F 2 28  ? -93.824  16.601  41.704  1.00 51.31  ? 28  ALA F C   1 
ATOM   8531  O O   . ALA F 2 28  ? -94.484  16.519  40.656  1.00 48.96  ? 28  ALA F O   1 
ATOM   8532  C CB  . ALA F 2 28  ? -93.088  14.532  42.898  1.00 37.00  ? 28  ALA F CB  1 
ATOM   8533  N N   . LYS F 2 29  ? -94.038  17.541  42.628  1.00 45.13  ? 29  LYS F N   1 
ATOM   8534  C CA  . LYS F 2 29  ? -95.067  18.555  42.460  1.00 48.08  ? 29  LYS F CA  1 
ATOM   8535  C C   . LYS F 2 29  ? -94.738  19.545  41.340  1.00 51.25  ? 29  LYS F C   1 
ATOM   8536  O O   . LYS F 2 29  ? -95.656  20.019  40.648  1.00 49.10  ? 29  LYS F O   1 
ATOM   8537  C CB  . LYS F 2 29  ? -95.276  19.266  43.792  1.00 50.54  ? 29  LYS F CB  1 
ATOM   8538  C CG  . LYS F 2 29  ? -95.968  18.367  44.821  1.00 50.09  ? 29  LYS F CG  1 
ATOM   8539  C CD  . LYS F 2 29  ? -95.637  18.752  46.248  1.00 44.09  ? 29  LYS F CD  1 
ATOM   8540  C CE  . LYS F 2 29  ? -96.703  18.231  47.189  1.00 47.43  ? 29  LYS F CE  1 
ATOM   8541  N NZ  . LYS F 2 29  ? -96.194  18.283  48.583  1.00 57.44  ? 29  LYS F NZ  1 
ATOM   8542  N N   . ILE F 2 30  ? -93.451  19.856  41.123  1.00 46.90  ? 30  ILE F N   1 
ATOM   8543  C CA  . ILE F 2 30  ? -93.097  20.738  40.006  1.00 44.87  ? 30  ILE F CA  1 
ATOM   8544  C C   . ILE F 2 30  ? -93.461  20.082  38.685  1.00 41.14  ? 30  ILE F C   1 
ATOM   8545  O O   . ILE F 2 30  ? -93.979  20.739  37.774  1.00 41.93  ? 30  ILE F O   1 
ATOM   8546  C CB  . ILE F 2 30  ? -91.605  21.137  40.064  1.00 44.05  ? 30  ILE F CB  1 
ATOM   8547  C CG1 . ILE F 2 30  ? -91.402  22.314  41.018  1.00 38.15  ? 30  ILE F CG1 1 
ATOM   8548  C CG2 . ILE F 2 30  ? -91.052  21.504  38.677  1.00 39.61  ? 30  ILE F CG2 1 
ATOM   8549  C CD1 . ILE F 2 30  ? -90.006  22.335  41.658  1.00 42.01  ? 30  ILE F CD1 1 
ATOM   8550  N N   . GLN F 2 31  ? -93.217  18.772  38.564  1.00 47.54  ? 31  GLN F N   1 
ATOM   8551  C CA  . GLN F 2 31  ? -93.675  18.041  37.383  1.00 48.48  ? 31  GLN F CA  1 
ATOM   8552  C C   . GLN F 2 31  ? -95.192  18.091  37.254  1.00 50.44  ? 31  GLN F C   1 
ATOM   8553  O O   . GLN F 2 31  ? -95.727  18.220  36.146  1.00 50.03  ? 31  GLN F O   1 
ATOM   8554  C CB  . GLN F 2 31  ? -93.203  16.595  37.431  1.00 48.03  ? 31  GLN F CB  1 
ATOM   8555  C CG  . GLN F 2 31  ? -93.637  15.755  36.236  1.00 48.44  ? 31  GLN F CG  1 
ATOM   8556  C CD  . GLN F 2 31  ? -93.323  14.290  36.446  1.00 51.01  ? 31  GLN F CD  1 
ATOM   8557  O OE1 . GLN F 2 31  ? -93.374  13.792  37.577  1.00 54.29  ? 31  GLN F OE1 1 
ATOM   8558  N NE2 . GLN F 2 31  ? -92.995  13.592  35.369  1.00 43.09  ? 31  GLN F NE2 1 
ATOM   8559  N N   . ASP F 2 32  ? -95.905  18.016  38.376  1.00 47.68  ? 32  ASP F N   1 
ATOM   8560  C CA  . ASP F 2 32  ? -97.353  18.158  38.314  1.00 44.16  ? 32  ASP F CA  1 
ATOM   8561  C C   . ASP F 2 32  ? -97.751  19.478  37.674  1.00 46.14  ? 32  ASP F C   1 
ATOM   8562  O O   . ASP F 2 32  ? -98.505  19.502  36.700  1.00 54.93  ? 32  ASP F O   1 
ATOM   8563  C CB  . ASP F 2 32  ? -97.955  18.050  39.705  1.00 50.12  ? 32  ASP F CB  1 
ATOM   8564  C CG  . ASP F 2 32  ? -99.430  18.344  39.710  1.00 51.93  ? 32  ASP F CG  1 
ATOM   8565  O OD1 . ASP F 2 32  ? -100.207 17.515  39.172  1.00 55.74  ? 32  ASP F OD1 1 
ATOM   8566  O OD2 . ASP F 2 32  ? -99.805  19.412  40.235  1.00 51.26  ? 32  ASP F OD2 1 
ATOM   8567  N N   . LYS F 2 33  ? -97.228  20.590  38.181  1.00 52.50  ? 33  LYS F N   1 
ATOM   8568  C CA  . LYS F 2 33  ? -97.694  21.897  37.716  1.00 50.01  ? 33  LYS F CA  1 
ATOM   8569  C C   . LYS F 2 33  ? -96.932  22.443  36.506  1.00 50.11  ? 33  LYS F C   1 
ATOM   8570  O O   . LYS F 2 33  ? -97.529  23.172  35.702  1.00 48.67  ? 33  LYS F O   1 
ATOM   8571  C CB  . LYS F 2 33  ? -97.644  22.903  38.863  1.00 43.65  ? 33  LYS F CB  1 
ATOM   8572  C CG  . LYS F 2 33  ? -98.705  23.947  38.772  1.00 48.39  ? 33  LYS F CG  1 
ATOM   8573  C CD  . LYS F 2 33  ? -98.428  25.166  39.652  1.00 47.56  ? 33  LYS F CD  1 
ATOM   8574  C CE  . LYS F 2 33  ? -99.470  25.252  40.749  1.00 49.19  ? 33  LYS F CE  1 
ATOM   8575  N NZ  . LYS F 2 33  ? -99.575  26.547  41.454  1.00 45.58  ? 33  LYS F NZ  1 
ATOM   8576  N N   . GLU F 2 34  ? -95.657  22.080  36.306  1.00 47.57  ? 34  GLU F N   1 
ATOM   8577  C CA  . GLU F 2 34  ? -94.897  22.624  35.189  1.00 46.14  ? 34  GLU F CA  1 
ATOM   8578  C C   . GLU F 2 34  ? -94.495  21.601  34.141  1.00 49.03  ? 34  GLU F C   1 
ATOM   8579  O O   . GLU F 2 34  ? -94.103  22.003  33.040  1.00 50.84  ? 34  GLU F O   1 
ATOM   8580  C CB  . GLU F 2 34  ? -93.624  23.317  35.688  1.00 48.85  ? 34  GLU F CB  1 
ATOM   8581  C CG  . GLU F 2 34  ? -93.766  24.810  35.971  1.00 56.75  ? 34  GLU F CG  1 
ATOM   8582  C CD  . GLU F 2 34  ? -93.825  25.717  34.724  1.00 56.61  ? 34  GLU F CD  1 
ATOM   8583  O OE1 . GLU F 2 34  ? -92.913  25.682  33.868  1.00 57.20  ? 34  GLU F OE1 1 
ATOM   8584  O OE2 . GLU F 2 34  ? -94.771  26.520  34.634  1.00 65.68  ? 34  GLU F OE2 1 
ATOM   8585  N N   . GLY F 2 35  ? -94.560  20.306  34.444  1.00 49.89  ? 35  GLY F N   1 
ATOM   8586  C CA  . GLY F 2 35  ? -94.251  19.281  33.464  1.00 40.02  ? 35  GLY F CA  1 
ATOM   8587  C C   . GLY F 2 35  ? -92.789  18.948  33.265  1.00 48.87  ? 35  GLY F C   1 
ATOM   8588  O O   . GLY F 2 35  ? -92.469  18.201  32.334  1.00 51.88  ? 35  GLY F O   1 
ATOM   8589  N N   . ILE F 2 36  ? -91.882  19.485  34.078  1.00 50.90  ? 36  ILE F N   1 
ATOM   8590  C CA  . ILE F 2 36  ? -90.466  19.132  33.958  1.00 47.64  ? 36  ILE F CA  1 
ATOM   8591  C C   . ILE F 2 36  ? -90.281  17.777  34.624  1.00 47.68  ? 36  ILE F C   1 
ATOM   8592  O O   . ILE F 2 36  ? -90.646  17.616  35.795  1.00 52.10  ? 36  ILE F O   1 
ATOM   8593  C CB  . ILE F 2 36  ? -89.546  20.182  34.609  1.00 45.31  ? 36  ILE F CB  1 
ATOM   8594  C CG1 . ILE F 2 36  ? -90.074  21.604  34.399  1.00 47.13  ? 36  ILE F CG1 1 
ATOM   8595  C CG2 . ILE F 2 36  ? -88.129  20.037  34.100  1.00 48.30  ? 36  ILE F CG2 1 
ATOM   8596  C CD1 . ILE F 2 36  ? -90.154  22.027  32.964  1.00 57.04  ? 36  ILE F CD1 1 
ATOM   8597  N N   . PRO F 2 37  ? -89.732  16.783  33.952  1.00 49.21  ? 37  PRO F N   1 
ATOM   8598  C CA  . PRO F 2 37  ? -89.381  15.544  34.651  1.00 54.13  ? 37  PRO F CA  1 
ATOM   8599  C C   . PRO F 2 37  ? -88.470  15.842  35.832  1.00 54.49  ? 37  PRO F C   1 
ATOM   8600  O O   . PRO F 2 37  ? -87.642  16.762  35.772  1.00 51.93  ? 37  PRO F O   1 
ATOM   8601  C CB  . PRO F 2 37  ? -88.659  14.720  33.573  1.00 54.58  ? 37  PRO F CB  1 
ATOM   8602  C CG  . PRO F 2 37  ? -89.039  15.346  32.274  1.00 53.95  ? 37  PRO F CG  1 
ATOM   8603  C CD  . PRO F 2 37  ? -89.261  16.800  32.563  1.00 51.70  ? 37  PRO F CD  1 
ATOM   8604  N N   . PRO F 2 38  ? -88.629  15.131  36.948  1.00 53.89  ? 38  PRO F N   1 
ATOM   8605  C CA  . PRO F 2 38  ? -87.742  15.375  38.102  1.00 54.35  ? 38  PRO F CA  1 
ATOM   8606  C C   . PRO F 2 38  ? -86.262  15.088  37.844  1.00 56.97  ? 38  PRO F C   1 
ATOM   8607  O O   . PRO F 2 38  ? -85.410  15.751  38.453  1.00 56.33  ? 38  PRO F O   1 
ATOM   8608  C CB  . PRO F 2 38  ? -88.325  14.451  39.176  1.00 48.97  ? 38  PRO F CB  1 
ATOM   8609  C CG  . PRO F 2 38  ? -89.766  14.392  38.844  1.00 52.13  ? 38  PRO F CG  1 
ATOM   8610  C CD  . PRO F 2 38  ? -89.849  14.407  37.337  1.00 53.75  ? 38  PRO F CD  1 
ATOM   8611  N N   . ASP F 2 39  ? -85.930  14.105  36.996  1.00 58.18  ? 39  ASP F N   1 
ATOM   8612  C CA  . ASP F 2 39  ? -84.554  13.863  36.563  1.00 55.80  ? 39  ASP F CA  1 
ATOM   8613  C C   . ASP F 2 39  ? -83.839  15.166  36.231  1.00 58.53  ? 39  ASP F C   1 
ATOM   8614  O O   . ASP F 2 39  ? -82.653  15.339  36.536  1.00 59.08  ? 39  ASP F O   1 
ATOM   8615  C CB  . ASP F 2 39  ? -84.510  12.993  35.303  1.00 57.83  ? 39  ASP F CB  1 
ATOM   8616  C CG  . ASP F 2 39  ? -84.777  11.552  35.574  1.00 69.01  ? 39  ASP F CG  1 
ATOM   8617  O OD1 . ASP F 2 39  ? -85.035  11.209  36.749  1.00 71.89  ? 39  ASP F OD1 1 
ATOM   8618  O OD2 . ASP F 2 39  ? -84.713  10.760  34.604  1.00 74.46  ? 39  ASP F OD2 1 
ATOM   8619  N N   . GLN F 2 40  ? -84.565  16.080  35.589  1.00 51.15  ? 40  GLN F N   1 
ATOM   8620  C CA  . GLN F 2 40  ? -83.970  17.216  34.912  1.00 52.09  ? 40  GLN F CA  1 
ATOM   8621  C C   . GLN F 2 40  ? -83.994  18.497  35.736  1.00 45.37  ? 40  GLN F C   1 
ATOM   8622  O O   . GLN F 2 40  ? -83.299  19.452  35.381  1.00 42.20  ? 40  GLN F O   1 
ATOM   8623  C CB  . GLN F 2 40  ? -84.680  17.447  33.576  1.00 54.87  ? 40  GLN F CB  1 
ATOM   8624  C CG  . GLN F 2 40  ? -84.468  16.353  32.515  1.00 61.03  ? 40  GLN F CG  1 
ATOM   8625  C CD  . GLN F 2 40  ? -85.028  16.761  31.142  1.00 67.92  ? 40  GLN F CD  1 
ATOM   8626  O OE1 . GLN F 2 40  ? -86.022  16.204  30.678  1.00 63.98  ? 40  GLN F OE1 1 
ATOM   8627  N NE2 . GLN F 2 40  ? -84.396  17.753  30.505  1.00 66.75  ? 40  GLN F NE2 1 
ATOM   8628  N N   . GLN F 2 41  ? -84.733  18.532  36.835  1.00 42.06  ? 41  GLN F N   1 
ATOM   8629  C CA  . GLN F 2 41  ? -84.824  19.742  37.631  1.00 44.57  ? 41  GLN F CA  1 
ATOM   8630  C C   . GLN F 2 41  ? -83.635  19.892  38.576  1.00 47.95  ? 41  GLN F C   1 
ATOM   8631  O O   . GLN F 2 41  ? -83.190  18.924  39.211  1.00 42.32  ? 41  GLN F O   1 
ATOM   8632  C CB  . GLN F 2 41  ? -86.114  19.739  38.444  1.00 42.33  ? 41  GLN F CB  1 
ATOM   8633  C CG  . GLN F 2 41  ? -87.309  19.269  37.688  1.00 43.24  ? 41  GLN F CG  1 
ATOM   8634  C CD  . GLN F 2 41  ? -88.494  19.110  38.590  1.00 48.47  ? 41  GLN F CD  1 
ATOM   8635  O OE1 . GLN F 2 41  ? -88.502  19.637  39.708  1.00 43.11  ? 41  GLN F OE1 1 
ATOM   8636  N NE2 . GLN F 2 41  ? -89.514  18.390  38.119  1.00 50.48  ? 41  GLN F NE2 1 
ATOM   8637  N N   . ARG F 2 42  ? -83.237  21.158  38.740  1.00 45.76  ? 42  ARG F N   1 
ATOM   8638  C CA  . ARG F 2 42  ? -82.200  21.540  39.722  1.00 41.04  ? 42  ARG F CA  1 
ATOM   8639  C C   . ARG F 2 42  ? -82.783  22.733  40.483  1.00 42.89  ? 42  ARG F C   1 
ATOM   8640  O O   . ARG F 2 42  ? -83.204  23.686  39.831  1.00 46.18  ? 42  ARG F O   1 
ATOM   8641  C CB  . ARG F 2 42  ? -80.893  21.892  39.021  1.00 38.49  ? 42  ARG F CB  1 
ATOM   8642  C CG  . ARG F 2 42  ? -80.254  20.737  38.265  1.00 45.98  ? 42  ARG F CG  1 
ATOM   8643  C CD  . ARG F 2 42  ? -79.043  21.214  37.502  1.00 49.91  ? 42  ARG F CD  1 
ATOM   8644  N NE  . ARG F 2 42  ? -78.345  22.185  38.317  1.00 58.17  ? 42  ARG F NE  1 
ATOM   8645  C CZ  . ARG F 2 42  ? -77.727  23.264  37.873  1.00 52.73  ? 42  ARG F CZ  1 
ATOM   8646  N NH1 . ARG F 2 42  ? -77.675  23.531  36.583  1.00 50.45  ? 42  ARG F NH1 1 
ATOM   8647  N NH2 . ARG F 2 42  ? -77.148  24.069  38.737  1.00 57.11  ? 42  ARG F NH2 1 
ATOM   8648  N N   . LEU F 2 43  ? -82.815  22.681  41.809  1.00 40.07  ? 43  LEU F N   1 
ATOM   8649  C CA  . LEU F 2 43  ? -83.450  23.715  42.611  1.00 43.75  ? 43  LEU F CA  1 
ATOM   8650  C C   . LEU F 2 43  ? -82.404  24.510  43.391  1.00 44.46  ? 43  LEU F C   1 
ATOM   8651  O O   . LEU F 2 43  ? -81.767  23.982  44.310  1.00 43.55  ? 43  LEU F O   1 
ATOM   8652  C CB  . LEU F 2 43  ? -84.482  23.092  43.545  1.00 45.08  ? 43  LEU F CB  1 
ATOM   8653  C CG  . LEU F 2 43  ? -85.748  22.662  42.801  1.00 49.43  ? 43  LEU F CG  1 
ATOM   8654  C CD1 . LEU F 2 43  ? -86.675  21.766  43.647  1.00 46.42  ? 43  LEU F CD1 1 
ATOM   8655  C CD2 . LEU F 2 43  ? -86.489  23.915  42.317  1.00 47.82  ? 43  LEU F CD2 1 
ATOM   8656  N N   . ILE F 2 44  ? -82.245  25.784  43.041  1.00 43.21  ? 44  ILE F N   1 
ATOM   8657  C CA  . ILE F 2 44  ? -81.334  26.682  43.743  1.00 47.67  ? 44  ILE F CA  1 
ATOM   8658  C C   . ILE F 2 44  ? -82.130  27.552  44.712  1.00 48.85  ? 44  ILE F C   1 
ATOM   8659  O O   . ILE F 2 44  ? -83.116  28.185  44.319  1.00 47.06  ? 44  ILE F O   1 
ATOM   8660  C CB  . ILE F 2 44  ? -80.540  27.559  42.764  1.00 45.26  ? 44  ILE F CB  1 
ATOM   8661  C CG1 . ILE F 2 44  ? -80.169  26.763  41.502  1.00 40.78  ? 44  ILE F CG1 1 
ATOM   8662  C CG2 . ILE F 2 44  ? -79.335  28.142  43.485  1.00 43.91  ? 44  ILE F CG2 1 
ATOM   8663  C CD1 . ILE F 2 44  ? -79.368  25.510  41.774  1.00 47.17  ? 44  ILE F CD1 1 
ATOM   8664  N N   . PHE F 2 45  ? -81.699  27.573  45.979  1.00 49.53  ? 45  PHE F N   1 
ATOM   8665  C CA  . PHE F 2 45  ? -82.264  28.409  47.036  1.00 48.98  ? 45  PHE F CA  1 
ATOM   8666  C C   . PHE F 2 45  ? -81.119  28.900  47.918  1.00 52.67  ? 45  PHE F C   1 
ATOM   8667  O O   . PHE F 2 45  ? -80.353  28.082  48.444  1.00 52.27  ? 45  PHE F O   1 
ATOM   8668  C CB  . PHE F 2 45  ? -83.287  27.629  47.873  1.00 47.01  ? 45  PHE F CB  1 
ATOM   8669  C CG  . PHE F 2 45  ? -83.706  28.337  49.136  1.00 44.50  ? 45  PHE F CG  1 
ATOM   8670  C CD1 . PHE F 2 45  ? -84.574  29.413  49.082  1.00 42.93  ? 45  PHE F CD1 1 
ATOM   8671  C CD2 . PHE F 2 45  ? -83.235  27.926  50.376  1.00 40.16  ? 45  PHE F CD2 1 
ATOM   8672  C CE1 . PHE F 2 45  ? -84.966  30.085  50.246  1.00 46.78  ? 45  PHE F CE1 1 
ATOM   8673  C CE2 . PHE F 2 45  ? -83.617  28.598  51.538  1.00 45.73  ? 45  PHE F CE2 1 
ATOM   8674  C CZ  . PHE F 2 45  ? -84.485  29.678  51.469  1.00 43.23  ? 45  PHE F CZ  1 
ATOM   8675  N N   . ALA F 2 46  ? -80.984  30.227  48.054  1.00 45.38  ? 46  ALA F N   1 
ATOM   8676  C CA  . ALA F 2 46  ? -79.993  30.852  48.952  1.00 48.06  ? 46  ALA F CA  1 
ATOM   8677  C C   . ALA F 2 46  ? -78.566  30.346  48.719  1.00 49.20  ? 46  ALA F C   1 
ATOM   8678  O O   . ALA F 2 46  ? -77.795  30.123  49.657  1.00 53.68  ? 46  ALA F O   1 
ATOM   8679  C CB  . ALA F 2 46  ? -80.383  30.661  50.412  1.00 40.91  ? 46  ALA F CB  1 
ATOM   8680  N N   . GLY F 2 47  ? -78.198  30.177  47.459  1.00 47.49  ? 47  GLY F N   1 
ATOM   8681  C CA  . GLY F 2 47  ? -76.882  29.735  47.103  1.00 46.65  ? 47  GLY F CA  1 
ATOM   8682  C C   . GLY F 2 47  ? -76.742  28.240  46.928  1.00 52.20  ? 47  GLY F C   1 
ATOM   8683  O O   . GLY F 2 47  ? -75.873  27.795  46.166  1.00 56.29  ? 47  GLY F O   1 
ATOM   8684  N N   . LYS F 2 48  ? -77.591  27.451  47.586  1.00 47.98  ? 48  LYS F N   1 
ATOM   8685  C CA  . LYS F 2 48  ? -77.376  26.013  47.718  1.00 54.90  ? 48  LYS F CA  1 
ATOM   8686  C C   . LYS F 2 48  ? -78.259  25.234  46.746  1.00 50.23  ? 48  LYS F C   1 
ATOM   8687  O O   . LYS F 2 48  ? -79.467  25.470  46.690  1.00 53.75  ? 48  LYS F O   1 
ATOM   8688  C CB  . LYS F 2 48  ? -77.661  25.568  49.160  1.00 55.26  ? 48  LYS F CB  1 
ATOM   8689  N N   . GLN F 2 49  ? -77.664  24.301  45.995  1.00 45.93  ? 49  GLN F N   1 
ATOM   8690  C CA  . GLN F 2 49  ? -78.461  23.344  45.226  1.00 49.18  ? 49  GLN F CA  1 
ATOM   8691  C C   . GLN F 2 49  ? -79.049  22.302  46.177  1.00 48.20  ? 49  GLN F C   1 
ATOM   8692  O O   . GLN F 2 49  ? -78.307  21.611  46.884  1.00 50.85  ? 49  GLN F O   1 
ATOM   8693  C CB  . GLN F 2 49  ? -77.643  22.667  44.123  1.00 41.27  ? 49  GLN F CB  1 
ATOM   8694  C CG  . GLN F 2 49  ? -78.508  21.811  43.138  1.00 44.00  ? 49  GLN F CG  1 
ATOM   8695  C CD  . GLN F 2 49  ? -77.790  21.469  41.804  1.00 46.68  ? 49  GLN F CD  1 
ATOM   8696  O OE1 . GLN F 2 49  ? -77.490  22.345  40.996  1.00 52.12  ? 49  GLN F OE1 1 
ATOM   8697  N NE2 . GLN F 2 49  ? -77.520  20.201  41.588  1.00 41.95  ? 49  GLN F NE2 1 
ATOM   8698  N N   . LEU F 2 50  ? -80.380  22.200  46.205  1.00 45.14  ? 50  LEU F N   1 
ATOM   8699  C CA  . LEU F 2 50  ? -81.052  21.236  47.068  1.00 45.53  ? 50  LEU F CA  1 
ATOM   8700  C C   . LEU F 2 50  ? -80.866  19.822  46.535  1.00 51.05  ? 50  LEU F C   1 
ATOM   8701  O O   . LEU F 2 50  ? -80.859  19.593  45.322  1.00 53.89  ? 50  LEU F O   1 
ATOM   8702  C CB  . LEU F 2 50  ? -82.539  21.558  47.155  1.00 45.34  ? 50  LEU F CB  1 
ATOM   8703  C CG  . LEU F 2 50  ? -82.913  23.032  47.301  1.00 45.28  ? 50  LEU F CG  1 
ATOM   8704  C CD1 . LEU F 2 50  ? -84.413  23.180  47.536  1.00 45.62  ? 50  LEU F CD1 1 
ATOM   8705  C CD2 . LEU F 2 50  ? -82.140  23.654  48.440  1.00 42.70  ? 50  LEU F CD2 1 
ATOM   8706  N N   . GLU F 2 51  ? -80.717  18.858  47.437  1.00 54.21  ? 51  GLU F N   1 
ATOM   8707  C CA  . GLU F 2 51  ? -80.370  17.509  47.012  1.00 57.40  ? 51  GLU F CA  1 
ATOM   8708  C C   . GLU F 2 51  ? -81.385  16.490  47.489  1.00 54.28  ? 51  GLU F C   1 
ATOM   8709  O O   . GLU F 2 51  ? -81.925  16.593  48.594  1.00 54.12  ? 51  GLU F O   1 
ATOM   8710  C CB  . GLU F 2 51  ? -79.007  17.110  47.509  1.00 54.29  ? 51  GLU F CB  1 
ATOM   8711  C CG  . GLU F 2 51  ? -78.733  17.674  48.853  1.00 56.25  ? 51  GLU F CG  1 
ATOM   8712  C CD  . GLU F 2 51  ? -77.263  17.760  49.115  1.00 62.38  ? 51  GLU F CD  1 
ATOM   8713  O OE1 . GLU F 2 51  ? -76.498  17.267  48.257  1.00 71.88  ? 51  GLU F OE1 1 
ATOM   8714  O OE2 . GLU F 2 51  ? -76.880  18.303  50.172  1.00 64.24  ? 51  GLU F OE2 1 
ATOM   8715  N N   . ASP F 2 52  ? -81.620  15.502  46.636  1.00 55.91  ? 52  ASP F N   1 
ATOM   8716  C CA  . ASP F 2 52  ? -82.529  14.421  46.965  1.00 56.25  ? 52  ASP F CA  1 
ATOM   8717  C C   . ASP F 2 52  ? -82.093  13.755  48.263  1.00 58.02  ? 52  ASP F C   1 
ATOM   8718  O O   . ASP F 2 52  ? -80.904  13.541  48.510  1.00 68.03  ? 52  ASP F O   1 
ATOM   8719  C CB  . ASP F 2 52  ? -82.571  13.405  45.815  1.00 52.96  ? 52  ASP F CB  1 
ATOM   8720  C CG  . ASP F 2 52  ? -83.192  13.983  44.552  1.00 57.26  ? 52  ASP F CG  1 
ATOM   8721  O OD1 . ASP F 2 52  ? -83.780  15.088  44.624  1.00 52.81  ? 52  ASP F OD1 1 
ATOM   8722  O OD2 . ASP F 2 52  ? -83.085  13.343  43.489  1.00 57.19  ? 52  ASP F OD2 1 
ATOM   8723  N N   . GLY F 2 53  ? -83.061  13.445  49.104  1.00 53.47  ? 53  GLY F N   1 
ATOM   8724  C CA  . GLY F 2 53  ? -82.752  12.830  50.366  1.00 50.73  ? 53  GLY F CA  1 
ATOM   8725  C C   . GLY F 2 53  ? -83.073  13.786  51.482  1.00 54.14  ? 53  GLY F C   1 
ATOM   8726  O O   . GLY F 2 53  ? -83.696  13.406  52.475  1.00 63.09  ? 53  GLY F O   1 
ATOM   8727  N N   . ARG F 2 54  ? -82.668  15.040  51.324  1.00 58.74  ? 54  ARG F N   1 
ATOM   8728  C CA  . ARG F 2 54  ? -82.943  16.018  52.363  1.00 63.70  ? 54  ARG F CA  1 
ATOM   8729  C C   . ARG F 2 54  ? -84.379  16.550  52.236  1.00 57.84  ? 54  ARG F C   1 
ATOM   8730  O O   . ARG F 2 54  ? -85.137  16.191  51.333  1.00 54.76  ? 54  ARG F O   1 
ATOM   8731  C CB  . ARG F 2 54  ? -81.898  17.138  52.316  1.00 58.64  ? 54  ARG F CB  1 
ATOM   8732  N N   . THR F 2 55  ? -84.774  17.398  53.173  1.00 57.11  ? 55  THR F N   1 
ATOM   8733  C CA  . THR F 2 55  ? -86.159  17.825  53.233  1.00 54.36  ? 55  THR F CA  1 
ATOM   8734  C C   . THR F 2 55  ? -86.213  19.334  53.400  1.00 55.57  ? 55  THR F C   1 
ATOM   8735  O O   . THR F 2 55  ? -85.252  19.953  53.851  1.00 56.95  ? 55  THR F O   1 
ATOM   8736  C CB  . THR F 2 55  ? -86.907  17.116  54.375  1.00 50.69  ? 55  THR F CB  1 
ATOM   8737  O OG1 . THR F 2 55  ? -88.319  17.252  54.178  1.00 64.55  ? 55  THR F OG1 1 
ATOM   8738  C CG2 . THR F 2 55  ? -86.535  17.715  55.716  1.00 46.47  ? 55  THR F CG2 1 
ATOM   8739  N N   . LEU F 2 56  ? -87.318  19.941  52.973  1.00 51.62  ? 56  LEU F N   1 
ATOM   8740  C CA  . LEU F 2 56  ? -87.423  21.424  52.946  1.00 52.72  ? 56  LEU F CA  1 
ATOM   8741  C C   . LEU F 2 56  ? -87.014  22.065  54.270  1.00 58.47  ? 56  LEU F C   1 
ATOM   8742  O O   . LEU F 2 56  ? -86.266  23.042  54.215  1.00 64.26  ? 56  LEU F O   1 
ATOM   8743  C CB  . LEU F 2 56  ? -88.857  21.807  52.582  1.00 53.99  ? 56  LEU F CB  1 
ATOM   8744  C CG  . LEU F 2 56  ? -89.222  21.705  51.106  1.00 51.95  ? 56  LEU F CG  1 
ATOM   8745  C CD1 . LEU F 2 56  ? -90.305  22.704  50.774  1.00 51.72  ? 56  LEU F CD1 1 
ATOM   8746  C CD2 . LEU F 2 56  ? -88.015  21.947  50.222  1.00 54.78  ? 56  LEU F CD2 1 
ATOM   8747  N N   . SER F 2 57  ? -87.521  21.581  55.400  1.00 56.07  ? 57  SER F N   1 
ATOM   8748  C CA  . SER F 2 57  ? -87.180  22.255  56.647  1.00 60.28  ? 57  SER F CA  1 
ATOM   8749  C C   . SER F 2 57  ? -85.682  22.206  56.903  1.00 57.38  ? 57  SER F C   1 
ATOM   8750  O O   . SER F 2 57  ? -85.149  23.105  57.556  1.00 59.84  ? 57  SER F O   1 
ATOM   8751  C CB  . SER F 2 57  ? -87.961  21.639  57.819  1.00 69.15  ? 57  SER F CB  1 
ATOM   8752  O OG  . SER F 2 57  ? -87.632  20.259  57.976  1.00 66.43  ? 57  SER F OG  1 
ATOM   8753  N N   . ASP F 2 58  ? -84.982  21.199  56.363  1.00 55.37  ? 58  ASP F N   1 
ATOM   8754  C CA  . ASP F 2 58  ? -83.528  21.144  56.519  1.00 55.37  ? 58  ASP F CA  1 
ATOM   8755  C C   . ASP F 2 58  ? -82.848  22.392  55.983  1.00 58.59  ? 58  ASP F C   1 
ATOM   8756  O O   . ASP F 2 58  ? -81.744  22.723  56.427  1.00 63.24  ? 58  ASP F O   1 
ATOM   8757  C CB  . ASP F 2 58  ? -82.933  19.918  55.818  1.00 53.91  ? 58  ASP F CB  1 
ATOM   8758  C CG  . ASP F 2 58  ? -83.269  18.615  56.525  1.00 62.24  ? 58  ASP F CG  1 
ATOM   8759  O OD1 . ASP F 2 58  ? -83.681  18.669  57.704  1.00 65.84  ? 58  ASP F OD1 1 
ATOM   8760  O OD2 . ASP F 2 58  ? -83.121  17.532  55.903  1.00 61.37  ? 58  ASP F OD2 1 
ATOM   8761  N N   . TYR F 2 59  ? -83.482  23.087  55.043  1.00 56.23  ? 59  TYR F N   1 
ATOM   8762  C CA  . TYR F 2 59  ? -82.975  24.332  54.503  1.00 49.75  ? 59  TYR F CA  1 
ATOM   8763  C C   . TYR F 2 59  ? -83.679  25.550  55.076  1.00 54.39  ? 59  TYR F C   1 
ATOM   8764  O O   . TYR F 2 59  ? -83.448  26.662  54.596  1.00 59.75  ? 59  TYR F O   1 
ATOM   8765  C CB  . TYR F 2 59  ? -83.113  24.333  52.986  1.00 48.08  ? 59  TYR F CB  1 
ATOM   8766  C CG  . TYR F 2 59  ? -82.347  23.239  52.315  1.00 47.29  ? 59  TYR F CG  1 
ATOM   8767  C CD1 . TYR F 2 59  ? -80.995  23.388  52.011  1.00 44.40  ? 59  TYR F CD1 1 
ATOM   8768  C CD2 . TYR F 2 59  ? -82.970  22.042  51.980  1.00 50.90  ? 59  TYR F CD2 1 
ATOM   8769  C CE1 . TYR F 2 59  ? -80.290  22.371  51.399  1.00 40.14  ? 59  TYR F CE1 1 
ATOM   8770  C CE2 . TYR F 2 59  ? -82.269  21.017  51.369  1.00 46.20  ? 59  TYR F CE2 1 
ATOM   8771  C CZ  . TYR F 2 59  ? -80.931  21.190  51.085  1.00 41.75  ? 59  TYR F CZ  1 
ATOM   8772  O OH  . TYR F 2 59  ? -80.244  20.188  50.464  1.00 45.66  ? 59  TYR F OH  1 
ATOM   8773  N N   . ASN F 2 60  ? -84.531  25.379  56.083  1.00 51.01  ? 60  ASN F N   1 
ATOM   8774  C CA  . ASN F 2 60  ? -85.353  26.485  56.583  1.00 55.18  ? 60  ASN F CA  1 
ATOM   8775  C C   . ASN F 2 60  ? -86.137  27.135  55.458  1.00 56.15  ? 60  ASN F C   1 
ATOM   8776  O O   . ASN F 2 60  ? -86.372  28.343  55.467  1.00 61.11  ? 60  ASN F O   1 
ATOM   8777  C CB  . ASN F 2 60  ? -84.518  27.543  57.310  1.00 61.75  ? 60  ASN F CB  1 
ATOM   8778  C CG  . ASN F 2 60  ? -84.068  27.089  58.682  1.00 77.19  ? 60  ASN F CG  1 
ATOM   8779  O OD1 . ASN F 2 60  ? -82.870  26.987  58.949  1.00 82.95  ? 60  ASN F OD1 1 
ATOM   8780  N ND2 . ASN F 2 60  ? -85.034  26.807  59.568  1.00 74.37  ? 60  ASN F ND2 1 
ATOM   8781  N N   . ILE F 2 61  ? -86.501  26.344  54.453  1.00 55.13  ? 61  ILE F N   1 
ATOM   8782  C CA  . ILE F 2 61  ? -87.463  26.806  53.469  1.00 52.26  ? 61  ILE F CA  1 
ATOM   8783  C C   . ILE F 2 61  ? -88.820  26.866  54.137  1.00 51.56  ? 61  ILE F C   1 
ATOM   8784  O O   . ILE F 2 61  ? -89.180  25.979  54.919  1.00 56.09  ? 61  ILE F O   1 
ATOM   8785  C CB  . ILE F 2 61  ? -87.467  25.876  52.244  1.00 52.75  ? 61  ILE F CB  1 
ATOM   8786  C CG1 . ILE F 2 61  ? -86.247  26.162  51.380  1.00 47.93  ? 61  ILE F CG1 1 
ATOM   8787  C CG2 . ILE F 2 61  ? -88.725  26.058  51.429  1.00 51.42  ? 61  ILE F CG2 1 
ATOM   8788  C CD1 . ILE F 2 61  ? -85.960  25.081  50.403  1.00 53.08  ? 61  ILE F CD1 1 
ATOM   8789  N N   . GLN F 2 62  ? -89.548  27.939  53.877  1.00 53.49  ? 62  GLN F N   1 
ATOM   8790  C CA  . GLN F 2 62  ? -90.861  28.101  54.518  1.00 57.35  ? 62  GLN F CA  1 
ATOM   8791  C C   . GLN F 2 62  ? -91.834  28.791  53.578  1.00 59.02  ? 62  GLN F C   1 
ATOM   8792  O O   . GLN F 2 62  ? -91.508  28.968  52.406  1.00 55.07  ? 62  GLN F O   1 
ATOM   8793  C CB  . GLN F 2 62  ? -90.690  28.950  55.775  1.00 53.13  ? 62  GLN F CB  1 
ATOM   8794  C CG  . GLN F 2 62  ? -89.975  30.270  55.546  1.00 49.72  ? 62  GLN F CG  1 
ATOM   8795  C CD  . GLN F 2 62  ? -89.573  30.893  56.857  1.00 68.46  ? 62  GLN F CD  1 
ATOM   8796  O OE1 . GLN F 2 62  ? -90.215  31.817  57.348  1.00 81.35  ? 62  GLN F OE1 1 
ATOM   8797  N NE2 . GLN F 2 62  ? -88.505  30.379  57.441  1.00 72.99  ? 62  GLN F NE2 1 
ATOM   8798  N N   . LYS F 2 63  ? -93.024  29.089  54.069  1.00 54.88  ? 63  LYS F N   1 
ATOM   8799  C CA  . LYS F 2 63  ? -93.982  29.892  53.324  1.00 51.19  ? 63  LYS F CA  1 
ATOM   8800  C C   . LYS F 2 63  ? -93.300  31.121  52.737  1.00 57.54  ? 63  LYS F C   1 
ATOM   8801  O O   . LYS F 2 63  ? -92.527  31.800  53.421  1.00 64.37  ? 63  LYS F O   1 
ATOM   8802  C CB  . LYS F 2 63  ? -95.122  30.310  54.251  1.00 50.07  ? 63  LYS F CB  1 
ATOM   8803  C CG  . LYS F 2 63  ? -96.186  31.163  53.583  1.00 56.00  ? 63  LYS F CG  1 
ATOM   8804  C CD  . LYS F 2 63  ? -97.108  31.803  54.617  1.00 53.53  ? 63  LYS F CD  1 
ATOM   8805  C CE  . LYS F 2 63  ? -98.427  32.233  54.008  1.00 50.45  ? 63  LYS F CE  1 
ATOM   8806  N NZ  . LYS F 2 63  ? -98.298  32.725  52.610  1.00 48.68  ? 63  LYS F NZ  1 
ATOM   8807  N N   . GLU F 2 64  ? -93.558  31.380  51.456  1.00 52.35  ? 64  GLU F N   1 
ATOM   8808  C CA  . GLU F 2 64  ? -93.081  32.536  50.689  1.00 53.82  ? 64  GLU F CA  1 
ATOM   8809  C C   . GLU F 2 64  ? -91.607  32.448  50.311  1.00 53.37  ? 64  GLU F C   1 
ATOM   8810  O O   . GLU F 2 64  ? -91.089  33.391  49.706  1.00 60.71  ? 64  GLU F O   1 
ATOM   8811  C CB  . GLU F 2 64  ? -93.335  33.881  51.400  1.00 52.66  ? 64  GLU F CB  1 
ATOM   8812  C CG  . GLU F 2 64  ? -94.812  34.304  51.448  1.00 54.52  ? 64  GLU F CG  1 
ATOM   8813  C CD  . GLU F 2 64  ? -95.203  35.189  52.644  1.00 62.44  ? 64  GLU F CD  1 
ATOM   8814  O OE1 . GLU F 2 64  ? -94.328  35.898  53.201  1.00 68.52  ? 64  GLU F OE1 1 
ATOM   8815  O OE2 . GLU F 2 64  ? -96.405  35.182  53.022  1.00 54.86  ? 64  GLU F OE2 1 
ATOM   8816  N N   . SER F 2 65  ? -90.914  31.356  50.618  1.00 52.15  ? 65  SER F N   1 
ATOM   8817  C CA  . SER F 2 65  ? -89.561  31.188  50.105  1.00 49.18  ? 65  SER F CA  1 
ATOM   8818  C C   . SER F 2 65  ? -89.602  30.920  48.610  1.00 49.73  ? 65  SER F C   1 
ATOM   8819  O O   . SER F 2 65  ? -90.468  30.193  48.117  1.00 53.51  ? 65  SER F O   1 
ATOM   8820  C CB  . SER F 2 65  ? -88.830  30.051  50.831  1.00 49.49  ? 65  SER F CB  1 
ATOM   8821  O OG  . SER F 2 65  ? -89.017  30.121  52.241  1.00 53.18  ? 65  SER F OG  1 
ATOM   8822  N N   . THR F 2 66  ? -88.670  31.524  47.883  1.00 48.10  ? 66  THR F N   1 
ATOM   8823  C CA  . THR F 2 66  ? -88.593  31.373  46.441  1.00 42.87  ? 66  THR F CA  1 
ATOM   8824  C C   . THR F 2 66  ? -87.511  30.356  46.100  1.00 49.70  ? 66  THR F C   1 
ATOM   8825  O O   . THR F 2 66  ? -86.360  30.498  46.520  1.00 53.96  ? 66  THR F O   1 
ATOM   8826  C CB  . THR F 2 66  ? -88.305  32.710  45.771  1.00 47.98  ? 66  THR F CB  1 
ATOM   8827  O OG1 . THR F 2 66  ? -89.398  33.614  45.998  1.00 51.81  ? 66  THR F OG1 1 
ATOM   8828  C CG2 . THR F 2 66  ? -88.098  32.520  44.280  1.00 48.52  ? 66  THR F CG2 1 
ATOM   8829  N N   . LEU F 2 67  ? -87.878  29.335  45.341  1.00 49.72  ? 67  LEU F N   1 
ATOM   8830  C CA  . LEU F 2 67  ? -86.927  28.371  44.802  1.00 48.37  ? 67  LEU F CA  1 
ATOM   8831  C C   . LEU F 2 67  ? -86.665  28.682  43.341  1.00 49.56  ? 67  LEU F C   1 
ATOM   8832  O O   . LEU F 2 67  ? -87.588  29.027  42.597  1.00 53.34  ? 67  LEU F O   1 
ATOM   8833  C CB  . LEU F 2 67  ? -87.444  26.934  44.898  1.00 49.36  ? 67  LEU F CB  1 
ATOM   8834  C CG  . LEU F 2 67  ? -87.348  26.154  46.198  1.00 49.83  ? 67  LEU F CG  1 
ATOM   8835  C CD1 . LEU F 2 67  ? -87.766  27.009  47.349  1.00 42.78  ? 67  LEU F CD1 1 
ATOM   8836  C CD2 . LEU F 2 67  ? -88.224  24.917  46.080  1.00 48.35  ? 67  LEU F CD2 1 
ATOM   8837  N N   . HIS F 2 68  ? -85.421  28.510  42.919  1.00 46.13  ? 68  HIS F N   1 
ATOM   8838  C CA  . HIS F 2 68  ? -85.017  28.870  41.571  1.00 44.67  ? 68  HIS F CA  1 
ATOM   8839  C C   . HIS F 2 68  ? -84.809  27.592  40.774  1.00 49.64  ? 68  HIS F C   1 
ATOM   8840  O O   . HIS F 2 68  ? -83.862  26.838  41.025  1.00 47.55  ? 68  HIS F O   1 
ATOM   8841  C CB  . HIS F 2 68  ? -83.778  29.766  41.603  1.00 42.75  ? 68  HIS F CB  1 
ATOM   8842  C CG  . HIS F 2 68  ? -84.047  31.085  42.240  1.00 45.71  ? 68  HIS F CG  1 
ATOM   8843  N ND1 . HIS F 2 68  ? -84.863  32.034  41.659  1.00 54.89  ? 68  HIS F ND1 1 
ATOM   8844  C CD2 . HIS F 2 68  ? -83.694  31.582  43.447  1.00 48.58  ? 68  HIS F CD2 1 
ATOM   8845  C CE1 . HIS F 2 68  ? -84.968  33.075  42.463  1.00 52.46  ? 68  HIS F CE1 1 
ATOM   8846  N NE2 . HIS F 2 68  ? -84.265  32.827  43.554  1.00 53.41  ? 68  HIS F NE2 1 
ATOM   8847  N N   . LEU F 2 69  ? -85.721  27.342  39.832  1.00 50.80  ? 69  LEU F N   1 
ATOM   8848  C CA  . LEU F 2 69  ? -85.653  26.153  39.001  1.00 46.17  ? 69  LEU F CA  1 
ATOM   8849  C C   . LEU F 2 69  ? -84.759  26.412  37.806  1.00 48.32  ? 69  LEU F C   1 
ATOM   8850  O O   . LEU F 2 69  ? -84.754  27.509  37.244  1.00 55.45  ? 69  LEU F O   1 
ATOM   8851  C CB  . LEU F 2 69  ? -87.039  25.746  38.526  1.00 45.58  ? 69  LEU F CB  1 
ATOM   8852  C CG  . LEU F 2 69  ? -86.963  24.589  37.529  1.00 48.17  ? 69  LEU F CG  1 
ATOM   8853  C CD1 . LEU F 2 69  ? -86.548  23.299  38.234  1.00 42.96  ? 69  LEU F CD1 1 
ATOM   8854  C CD2 . LEU F 2 69  ? -88.253  24.423  36.747  1.00 50.39  ? 69  LEU F CD2 1 
ATOM   8855  N N   . VAL F 2 70  ? -83.914  25.429  37.527  1.00 46.20  ? 70  VAL F N   1 
ATOM   8856  C CA  . VAL F 2 70  ? -82.899  25.575  36.464  1.00 45.04  ? 70  VAL F CA  1 
ATOM   8857  C C   . VAL F 2 70  ? -82.655  24.182  35.883  1.00 50.92  ? 70  VAL F C   1 
ATOM   8858  O O   . VAL F 2 70  ? -83.016  23.193  36.533  1.00 52.21  ? 70  VAL F O   1 
ATOM   8859  C CB  . VAL F 2 70  ? -81.660  26.214  37.114  1.00 50.72  ? 70  VAL F CB  1 
ATOM   8860  C CG1 . VAL F 2 70  ? -80.446  25.319  37.204  1.00 50.76  ? 70  VAL F CG1 1 
ATOM   8861  C CG2 . VAL F 2 70  ? -81.324  27.554  36.508  1.00 54.03  ? 70  VAL F CG2 1 
ATOM   8862  N N   . LEU F 2 71  ? -82.130  24.115  34.665  1.00 45.22  ? 71  LEU F N   1 
ATOM   8863  C CA  . LEU F 2 71  ? -81.868  22.810  34.023  1.00 41.69  ? 71  LEU F CA  1 
ATOM   8864  C C   . LEU F 2 71  ? -80.365  22.567  33.928  1.00 48.23  ? 71  LEU F C   1 
ATOM   8865  O O   . LEU F 2 71  ? -79.641  23.073  34.778  1.00 46.29  ? 71  LEU F O   1 
ATOM   8866  C CB  . LEU F 2 71  ? -82.513  22.784  32.638  1.00 41.41  ? 71  LEU F CB  1 
ATOM   8867  C CG  . LEU F 2 71  ? -84.035  22.732  32.566  1.00 50.01  ? 71  LEU F CG  1 
ATOM   8868  C CD1 . LEU F 2 71  ? -84.482  22.246  31.199  1.00 51.47  ? 71  LEU F CD1 1 
ATOM   8869  C CD2 . LEU F 2 71  ? -84.625  21.854  33.652  1.00 50.01  ? 71  LEU F CD2 1 
ATOM   8870  N N   . ARG F 2 72  ? -79.918  21.849  32.901  1.00 46.10  ? 72  ARG F N   1 
ATOM   8871  C CA  . ARG F 2 72  ? -78.529  21.438  32.790  1.00 48.59  ? 72  ARG F CA  1 
ATOM   8872  C C   . ARG F 2 72  ? -78.036  21.677  31.365  1.00 50.70  ? 72  ARG F C   1 
ATOM   8873  O O   . ARG F 2 72  ? -78.762  21.426  30.395  1.00 48.85  ? 72  ARG F O   1 
ATOM   8874  C CB  . ARG F 2 72  ? -78.358  19.936  33.139  1.00 44.39  ? 72  ARG F CB  1 
ATOM   8875  C CG  . ARG F 2 72  ? -77.937  19.613  34.528  1.00 43.74  ? 72  ARG F CG  1 
ATOM   8876  C CD  . ARG F 2 72  ? -77.874  18.093  34.772  1.00 50.72  ? 72  ARG F CD  1 
ATOM   8877  N NE  . ARG F 2 72  ? -77.834  17.765  36.205  1.00 50.52  ? 72  ARG F NE  1 
ATOM   8878  C CZ  . ARG F 2 72  ? -78.905  17.434  36.916  1.00 43.77  ? 72  ARG F CZ  1 
ATOM   8879  N NH1 . ARG F 2 72  ? -80.093  17.364  36.340  1.00 45.78  ? 72  ARG F NH1 1 
ATOM   8880  N NH2 . ARG F 2 72  ? -78.794  17.172  38.194  1.00 44.35  ? 72  ARG F NH2 1 
ATOM   8881  N N   . LEU F 2 73  ? -76.786  22.121  31.255  1.00 42.76  ? 73  LEU F N   1 
ATOM   8882  C CA  . LEU F 2 73  ? -76.121  22.245  29.937  1.00 53.42  ? 73  LEU F CA  1 
ATOM   8883  C C   . LEU F 2 73  ? -74.825  21.461  30.105  1.00 58.08  ? 73  LEU F C   1 
ATOM   8884  O O   . LEU F 2 73  ? -73.861  22.043  30.579  1.00 54.14  ? 73  LEU F O   1 
ATOM   8885  C CB  . LEU F 2 73  ? -75.891  23.717  29.591  1.00 55.93  ? 73  LEU F CB  1 
ATOM   8886  C CG  . LEU F 2 73  ? -76.962  24.353  28.710  1.00 52.77  ? 73  LEU F CG  1 
ATOM   8887  C CD1 . LEU F 2 73  ? -76.500  25.699  28.188  1.00 54.17  ? 73  LEU F CD1 1 
ATOM   8888  C CD2 . LEU F 2 73  ? -77.321  23.432  27.559  1.00 55.26  ? 73  LEU F CD2 1 
ATOM   8889  N N   . ARG F 2 74  ? -74.817  20.184  29.735  1.00 58.75  ? 74  ARG F N   1 
ATOM   8890  C CA  . ARG F 2 74  ? -73.693  19.295  29.997  1.00 58.20  ? 74  ARG F CA  1 
ATOM   8891  C C   . ARG F 2 74  ? -72.610  19.482  28.940  1.00 64.08  ? 74  ARG F C   1 
ATOM   8892  O O   . ARG F 2 74  ? -72.903  19.750  27.768  1.00 64.36  ? 74  ARG F O   1 
ATOM   8893  C CB  . ARG F 2 74  ? -74.164  17.832  30.061  1.00 50.19  ? 74  ARG F CB  1 
ATOM   8894  C CG  . ARG F 2 74  ? -75.399  17.646  30.948  1.00 60.00  ? 74  ARG F CG  1 
ATOM   8895  C CD  . ARG F 2 74  ? -75.773  16.186  31.223  1.00 51.08  ? 74  ARG F CD  1 
ATOM   8896  N NE  . ARG F 2 74  ? -75.425  15.815  32.583  1.00 51.03  ? 74  ARG F NE  1 
ATOM   8897  C CZ  . ARG F 2 74  ? -76.287  15.388  33.491  1.00 52.77  ? 74  ARG F CZ  1 
ATOM   8898  N NH1 . ARG F 2 74  ? -77.570  15.276  33.191  1.00 59.70  ? 74  ARG F NH1 1 
ATOM   8899  N NH2 . ARG F 2 74  ? -75.861  15.084  34.707  1.00 58.73  ? 74  ARG F NH2 1 
ATOM   8900  N N   . GLY F 2 75  ? -71.353  19.369  29.365  1.00 56.69  ? 75  GLY F N   1 
ATOM   8901  C CA  . GLY F 2 75  ? -70.257  19.561  28.440  1.00 59.53  ? 75  GLY F CA  1 
ATOM   8902  C C   . GLY F 2 75  ? -69.040  18.697  28.695  1.00 63.29  ? 75  GLY F C   1 
ATOM   8903  O O   . GLY F 2 75  ? -68.566  18.609  29.828  1.00 62.83  ? 75  GLY F O   1 
ATOM   8904  N N   . TYR G 1 6   ? -22.541  14.324  1.312   1.00 89.93  ? 213 TYR G N   1 
ATOM   8905  C CA  . TYR G 1 6   ? -21.771  13.461  2.244   1.00 91.67  ? 213 TYR G CA  1 
ATOM   8906  C C   . TYR G 1 6   ? -22.124  11.991  2.006   1.00 85.64  ? 213 TYR G C   1 
ATOM   8907  O O   . TYR G 1 6   ? -23.137  11.707  1.345   1.00 81.75  ? 213 TYR G O   1 
ATOM   8908  C CB  . TYR G 1 6   ? -22.036  13.856  3.699   1.00 79.49  ? 213 TYR G CB  1 
ATOM   8909  C CG  . TYR G 1 6   ? -21.538  15.217  4.113   1.00 80.19  ? 213 TYR G CG  1 
ATOM   8910  C CD1 . TYR G 1 6   ? -20.279  15.665  3.751   1.00 68.59  ? 213 TYR G CD1 1 
ATOM   8911  C CD2 . TYR G 1 6   ? -22.326  16.055  4.882   1.00 82.30  ? 213 TYR G CD2 1 
ATOM   8912  C CE1 . TYR G 1 6   ? -19.821  16.914  4.136   1.00 71.65  ? 213 TYR G CE1 1 
ATOM   8913  C CE2 . TYR G 1 6   ? -21.885  17.306  5.274   1.00 77.82  ? 213 TYR G CE2 1 
ATOM   8914  C CZ  . TYR G 1 6   ? -20.627  17.738  4.900   1.00 76.87  ? 213 TYR G CZ  1 
ATOM   8915  O OH  . TYR G 1 6   ? -20.188  18.971  5.283   1.00 65.95  ? 213 TYR G OH  1 
ATOM   8916  N N   . VAL G 1 7   ? -21.305  11.088  2.541   1.00 83.33  ? 214 VAL G N   1 
ATOM   8917  C CA  . VAL G 1 7   ? -21.549  9.627   2.368   1.00 84.41  ? 214 VAL G CA  1 
ATOM   8918  C C   . VAL G 1 7   ? -21.667  8.960   3.742   1.00 88.59  ? 214 VAL G C   1 
ATOM   8919  O O   . VAL G 1 7   ? -21.195  9.545   4.734   1.00 85.26  ? 214 VAL G O   1 
ATOM   8920  C CB  . VAL G 1 7   ? -20.454  8.991   1.490   1.00 82.81  ? 214 VAL G CB  1 
ATOM   8921  C CG1 . VAL G 1 7   ? -19.180  8.700   2.256   1.00 89.20  ? 214 VAL G CG1 1 
ATOM   8922  C CG2 . VAL G 1 7   ? -20.941  7.757   0.751   1.00 82.76  ? 214 VAL G CG2 1 
ATOM   8923  N N   . GLY G 1 8   ? -22.273  7.778   3.761   1.00 89.42  ? 215 GLY G N   1 
ATOM   8924  C CA  . GLY G 1 8   ? -22.449  7.052   5.022   1.00 79.84  ? 215 GLY G CA  1 
ATOM   8925  C C   . GLY G 1 8   ? -21.516  5.877   5.173   1.00 86.31  ? 215 GLY G C   1 
ATOM   8926  O O   . GLY G 1 8   ? -20.757  5.586   4.238   1.00 85.01  ? 215 GLY G O   1 
ATOM   8927  N N   . LEU G 1 9   ? -21.582  5.224   6.322   1.00 90.83  ? 216 LEU G N   1 
ATOM   8928  C CA  . LEU G 1 9   ? -20.754  4.066   6.647   1.00 86.63  ? 216 LEU G CA  1 
ATOM   8929  C C   . LEU G 1 9   ? -21.657  2.882   6.987   1.00 82.30  ? 216 LEU G C   1 
ATOM   8930  O O   . LEU G 1 9   ? -22.567  3.004   7.814   1.00 79.11  ? 216 LEU G O   1 
ATOM   8931  C CB  . LEU G 1 9   ? -19.796  4.387   7.805   1.00 82.61  ? 216 LEU G CB  1 
ATOM   8932  N N   . LYS G 1 10  ? -21.399  1.739   6.350   1.00 82.83  ? 217 LYS G N   1 
ATOM   8933  C CA  . LYS G 1 10  ? -22.293  0.589   6.426   1.00 83.66  ? 217 LYS G CA  1 
ATOM   8934  C C   . LYS G 1 10  ? -22.110  -0.202  7.718   1.00 86.54  ? 217 LYS G C   1 
ATOM   8935  O O   . LYS G 1 10  ? -21.010  -0.298  8.276   1.00 90.45  ? 217 LYS G O   1 
ATOM   8936  C CB  . LYS G 1 10  ? -22.073  -0.354  5.241   1.00 82.92  ? 217 LYS G CB  1 
ATOM   8937  C CG  . LYS G 1 10  ? -22.058  0.304   3.884   1.00 74.77  ? 217 LYS G CG  1 
ATOM   8938  C CD  . LYS G 1 10  ? -21.787  -0.726  2.807   1.00 87.46  ? 217 LYS G CD  1 
ATOM   8939  C CE  . LYS G 1 10  ? -20.696  -1.709  3.216   1.00 86.52  ? 217 LYS G CE  1 
ATOM   8940  N NZ  . LYS G 1 10  ? -20.489  -2.726  2.151   1.00 86.22  ? 217 LYS G NZ  1 
ATOM   8941  N N   . ASN G 1 11  ? -23.217  -0.789  8.186   1.00 85.04  ? 218 ASN G N   1 
ATOM   8942  C CA  . ASN G 1 11  ? -23.204  -1.561  9.456   1.00 83.64  ? 218 ASN G CA  1 
ATOM   8943  C C   . ASN G 1 11  ? -22.931  -3.035  9.173   1.00 86.28  ? 218 ASN G C   1 
ATOM   8944  O O   . ASN G 1 11  ? -23.684  -3.639  8.392   1.00 85.31  ? 218 ASN G O   1 
ATOM   8945  C CB  . ASN G 1 11  ? -24.532  -1.429  10.204  1.00 82.91  ? 218 ASN G CB  1 
ATOM   8946  C CG  . ASN G 1 11  ? -24.446  -1.758  11.677  1.00 83.67  ? 218 ASN G CG  1 
ATOM   8947  O OD1 . ASN G 1 11  ? -23.456  -2.312  12.136  1.00 83.15  ? 218 ASN G OD1 1 
ATOM   8948  N ND2 . ASN G 1 11  ? -25.485  -1.427  12.423  1.00 85.52  ? 218 ASN G ND2 1 
ATOM   8949  N N   . GLN G 1 12  ? -21.904  -3.588  9.815   1.00 81.70  ? 219 GLN G N   1 
ATOM   8950  C CA  . GLN G 1 12  ? -21.611  -5.034  9.667   1.00 83.52  ? 219 GLN G CA  1 
ATOM   8951  C C   . GLN G 1 12  ? -22.676  -5.831  10.432  1.00 79.95  ? 219 GLN G C   1 
ATOM   8952  O O   . GLN G 1 12  ? -22.814  -7.034  10.161  1.00 76.11  ? 219 GLN G O   1 
ATOM   8953  C CB  . GLN G 1 12  ? -20.200  -5.312  10.179  1.00 74.88  ? 219 GLN G CB  1 
ATOM   8954  C CG  . GLN G 1 12  ? -19.115  -4.580  9.408   1.00 79.65  ? 219 GLN G CG  1 
ATOM   8955  C CD  . GLN G 1 12  ? -17.736  -5.085  9.752   1.00 84.79  ? 219 GLN G CD  1 
ATOM   8956  O OE1 . GLN G 1 12  ? -16.836  -4.314  10.066  1.00 80.48  ? 219 GLN G OE1 1 
ATOM   8957  N NE2 . GLN G 1 12  ? -17.559  -6.394  9.692   1.00 82.23  ? 219 GLN G NE2 1 
ATOM   8958  N N   . GLY G 1 13  ? -23.405  -5.178  11.337  1.00 75.27  ? 220 GLY G N   1 
ATOM   8959  C CA  . GLY G 1 13  ? -24.439  -5.842  12.148  1.00 75.81  ? 220 GLY G CA  1 
ATOM   8960  C C   . GLY G 1 13  ? -24.738  -5.033  13.394  1.00 78.99  ? 220 GLY G C   1 
ATOM   8961  O O   . GLY G 1 13  ? -25.917  -4.725  13.622  1.00 82.60  ? 220 GLY G O   1 
ATOM   8962  N N   . ALA G 1 14  ? -23.703  -4.673  14.152  1.00 77.04  ? 221 ALA G N   1 
ATOM   8963  C CA  . ALA G 1 14  ? -23.897  -3.893  15.394  1.00 81.23  ? 221 ALA G CA  1 
ATOM   8964  C C   . ALA G 1 14  ? -22.787  -2.857  15.590  1.00 76.49  ? 221 ALA G C   1 
ATOM   8965  O O   . ALA G 1 14  ? -22.551  -2.481  16.742  1.00 70.84  ? 221 ALA G O   1 
ATOM   8966  C CB  . ALA G 1 14  ? -23.990  -4.830  16.564  1.00 79.30  ? 221 ALA G CB  1 
ATOM   8967  N N   . THR G 1 15  ? -22.137  -2.413  14.516  1.00 68.06  ? 222 THR G N   1 
ATOM   8968  C CA  . THR G 1 15  ? -21.155  -1.341  14.613  1.00 67.30  ? 222 THR G CA  1 
ATOM   8969  C C   . THR G 1 15  ? -21.788  0.061   14.592  1.00 65.34  ? 222 THR G C   1 
ATOM   8970  O O   . THR G 1 15  ? -21.172  0.998   14.084  1.00 61.31  ? 222 THR G O   1 
ATOM   8971  C CB  . THR G 1 15  ? -20.087  -1.494  13.513  1.00 67.45  ? 222 THR G CB  1 
ATOM   8972  O OG1 . THR G 1 15  ? -20.657  -1.400  12.210  1.00 78.07  ? 222 THR G OG1 1 
ATOM   8973  C CG2 . THR G 1 15  ? -19.409  -2.838  13.615  1.00 67.60  ? 222 THR G CG2 1 
ATOM   8974  N N   . CYS G 1 16  ? -22.968  0.216   15.167  1.00 68.76  ? 223 CYS G N   1 
ATOM   8975  C CA  . CYS G 1 16  ? -23.556  1.570   15.278  1.00 68.20  ? 223 CYS G CA  1 
ATOM   8976  C C   . CYS G 1 16  ? -22.506  2.501   15.877  1.00 67.05  ? 223 CYS G C   1 
ATOM   8977  O O   . CYS G 1 16  ? -22.313  3.589   15.330  1.00 60.18  ? 223 CYS G O   1 
ATOM   8978  C CB  . CYS G 1 16  ? -24.766  1.512   16.200  1.00 59.43  ? 223 CYS G CB  1 
ATOM   8979  S SG  . CYS G 1 16  ? -25.558  -0.112  16.289  1.00 77.25  ? 223 CYS G SG  1 
ATOM   8980  N N   . TYR G 1 17  ? -21.844  2.068   16.946  1.00 66.47  ? 224 TYR G N   1 
ATOM   8981  C CA  . TYR G 1 17  ? -20.830  2.871   17.676  1.00 68.24  ? 224 TYR G CA  1 
ATOM   8982  C C   . TYR G 1 17  ? -19.655  3.290   16.803  1.00 71.71  ? 224 TYR G C   1 
ATOM   8983  O O   . TYR G 1 17  ? -19.338  4.484   16.767  1.00 72.33  ? 224 TYR G O   1 
ATOM   8984  C CB  . TYR G 1 17  ? -20.361  2.060   18.893  1.00 67.02  ? 224 TYR G CB  1 
ATOM   8985  C CG  . TYR G 1 17  ? -19.664  0.751   18.613  1.00 67.60  ? 224 TYR G CG  1 
ATOM   8986  C CD1 . TYR G 1 17  ? -20.373  -0.383  18.259  1.00 66.13  ? 224 TYR G CD1 1 
ATOM   8987  C CD2 . TYR G 1 17  ? -18.287  0.645   18.706  1.00 63.80  ? 224 TYR G CD2 1 
ATOM   8988  C CE1 . TYR G 1 17  ? -19.733  -1.578  17.984  1.00 64.78  ? 224 TYR G CE1 1 
ATOM   8989  C CE2 . TYR G 1 17  ? -17.629  -0.539  18.422  1.00 66.15  ? 224 TYR G CE2 1 
ATOM   8990  C CZ  . TYR G 1 17  ? -18.357  -1.656  18.063  1.00 68.45  ? 224 TYR G CZ  1 
ATOM   8991  O OH  . TYR G 1 17  ? -17.728  -2.836  17.802  1.00 70.78  ? 224 TYR G OH  1 
ATOM   8992  N N   . MET G 1 18  ? -19.011  2.330   16.155  1.00 69.53  ? 225 MET G N   1 
ATOM   8993  C CA  . MET G 1 18  ? -17.823  2.654   15.366  1.00 70.51  ? 225 MET G CA  1 
ATOM   8994  C C   . MET G 1 18  ? -18.172  3.533   14.172  1.00 71.04  ? 225 MET G C   1 
ATOM   8995  O O   . MET G 1 18  ? -17.353  4.349   13.730  1.00 71.38  ? 225 MET G O   1 
ATOM   8996  C CB  . MET G 1 18  ? -17.149  1.362   14.903  1.00 69.11  ? 225 MET G CB  1 
ATOM   8997  C CG  . MET G 1 18  ? -15.766  1.536   14.366  1.00 65.64  ? 225 MET G CG  1 
ATOM   8998  S SD  . MET G 1 18  ? -15.136  -0.027  13.749  1.00 67.56  ? 225 MET G SD  1 
ATOM   8999  C CE  . MET G 1 18  ? -16.188  -0.209  12.327  1.00 75.92  ? 225 MET G CE  1 
ATOM   9000  N N   . ASN G 1 19  ? -19.370  3.360   13.622  1.00 73.45  ? 226 ASN G N   1 
ATOM   9001  C CA  . ASN G 1 19  ? -19.801  4.233   12.546  1.00 69.66  ? 226 ASN G CA  1 
ATOM   9002  C C   . ASN G 1 19  ? -19.913  5.660   13.053  1.00 73.40  ? 226 ASN G C   1 
ATOM   9003  O O   . ASN G 1 19  ? -19.365  6.589   12.445  1.00 77.05  ? 226 ASN G O   1 
ATOM   9004  C CB  . ASN G 1 19  ? -21.131  3.755   11.965  1.00 61.88  ? 226 ASN G CB  1 
ATOM   9005  C CG  . ASN G 1 19  ? -20.964  2.671   10.912  1.00 68.07  ? 226 ASN G CG  1 
ATOM   9006  O OD1 . ASN G 1 19  ? -19.873  2.151   10.693  1.00 73.58  ? 226 ASN G OD1 1 
ATOM   9007  N ND2 . ASN G 1 19  ? -22.061  2.317   10.262  1.00 76.49  ? 226 ASN G ND2 1 
ATOM   9008  N N   . SER G 1 20  ? -20.595  5.852   14.185  1.00 65.46  ? 227 SER G N   1 
ATOM   9009  C CA  . SER G 1 20  ? -20.851  7.212   14.635  1.00 69.97  ? 227 SER G CA  1 
ATOM   9010  C C   . SER G 1 20  ? -19.551  7.952   14.905  1.00 73.25  ? 227 SER G C   1 
ATOM   9011  O O   . SER G 1 20  ? -19.473  9.165   14.689  1.00 78.73  ? 227 SER G O   1 
ATOM   9012  C CB  . SER G 1 20  ? -21.738  7.213   15.884  1.00 70.29  ? 227 SER G CB  1 
ATOM   9013  O OG  . SER G 1 20  ? -22.781  6.261   15.795  1.00 67.17  ? 227 SER G OG  1 
ATOM   9014  N N   . LEU G 1 21  ? -18.522  7.240   15.367  1.00 68.67  ? 228 LEU G N   1 
ATOM   9015  C CA  . LEU G 1 21  ? -17.251  7.900   15.774  1.00 69.94  ? 228 LEU G CA  1 
ATOM   9016  C C   . LEU G 1 21  ? -16.335  8.133   14.577  1.00 71.31  ? 228 LEU G C   1 
ATOM   9017  O O   . LEU G 1 21  ? -15.686  9.164   14.542  1.00 71.52  ? 228 LEU G O   1 
ATOM   9018  C CB  . LEU G 1 21  ? -16.550  7.012   16.803  1.00 75.36  ? 228 LEU G CB  1 
ATOM   9019  C CG  . LEU G 1 21  ? -15.441  7.681   17.609  1.00 67.32  ? 228 LEU G CG  1 
ATOM   9020  C CD1 . LEU G 1 21  ? -16.000  8.315   18.870  1.00 69.74  ? 228 LEU G CD1 1 
ATOM   9021  C CD2 . LEU G 1 21  ? -14.354  6.679   17.950  1.00 64.76  ? 228 LEU G CD2 1 
ATOM   9022  N N   . LEU G 1 22  ? -16.255  7.174   13.664  1.00 73.53  ? 229 LEU G N   1 
ATOM   9023  C CA  . LEU G 1 22  ? -15.414  7.332   12.454  1.00 71.96  ? 229 LEU G CA  1 
ATOM   9024  C C   . LEU G 1 22  ? -15.832  8.619   11.759  1.00 73.75  ? 229 LEU G C   1 
ATOM   9025  O O   . LEU G 1 22  ? -14.950  9.300   11.257  1.00 75.12  ? 229 LEU G O   1 
ATOM   9026  C CB  . LEU G 1 22  ? -15.619  6.125   11.542  1.00 71.56  ? 229 LEU G CB  1 
ATOM   9027  C CG  . LEU G 1 22  ? -14.766  4.905   11.867  1.00 68.77  ? 229 LEU G CG  1 
ATOM   9028  C CD1 . LEU G 1 22  ? -15.155  3.740   10.975  1.00 71.18  ? 229 LEU G CD1 1 
ATOM   9029  C CD2 . LEU G 1 22  ? -13.295  5.236   11.719  1.00 68.04  ? 229 LEU G CD2 1 
ATOM   9030  N N   . GLN G 1 23  ? -17.130  8.908   11.705  1.00 74.45  ? 230 GLN G N   1 
ATOM   9031  C CA  . GLN G 1 23  ? -17.595  10.185  11.176  1.00 73.59  ? 230 GLN G CA  1 
ATOM   9032  C C   . GLN G 1 23  ? -17.090  11.340  12.029  1.00 74.35  ? 230 GLN G C   1 
ATOM   9033  O O   . GLN G 1 23  ? -16.480  12.281  11.513  1.00 78.04  ? 230 GLN G O   1 
ATOM   9034  C CB  . GLN G 1 23  ? -19.126  10.189  11.099  1.00 75.18  ? 230 GLN G CB  1 
ATOM   9035  C CG  . GLN G 1 23  ? -19.697  9.173   10.090  1.00 77.28  ? 230 GLN G CG  1 
ATOM   9036  C CD  . GLN G 1 23  ? -19.906  9.763   8.701   1.00 80.33  ? 230 GLN G CD  1 
ATOM   9037  O OE1 . GLN G 1 23  ? -19.127  9.506   7.784   1.00 77.72  ? 230 GLN G OE1 1 
ATOM   9038  N NE2 . GLN G 1 23  ? -20.964  10.557  8.540   1.00 86.72  ? 230 GLN G NE2 1 
ATOM   9039  N N   . THR G 1 24  ? -17.293  11.260  13.340  1.00 79.07  ? 231 THR G N   1 
ATOM   9040  C CA  . THR G 1 24  ? -16.776  12.306  14.259  1.00 76.26  ? 231 THR G CA  1 
ATOM   9041  C C   . THR G 1 24  ? -15.284  12.530  14.006  1.00 74.36  ? 231 THR G C   1 
ATOM   9042  O O   . THR G 1 24  ? -14.893  13.695  13.866  1.00 74.41  ? 231 THR G O   1 
ATOM   9043  C CB  . THR G 1 24  ? -17.054  11.931  15.719  1.00 69.79  ? 231 THR G CB  1 
ATOM   9044  O OG1 . THR G 1 24  ? -18.457  11.729  15.880  1.00 72.49  ? 231 THR G OG1 1 
ATOM   9045  C CG2 . THR G 1 24  ? -16.578  12.977  16.700  1.00 72.93  ? 231 THR G CG2 1 
ATOM   9046  N N   . LEU G 1 25  ? -14.492  11.461  13.918  1.00 70.80  ? 232 LEU G N   1 
ATOM   9047  C CA  . LEU G 1 25  ? -13.023  11.632  13.785  1.00 74.12  ? 232 LEU G CA  1 
ATOM   9048  C C   . LEU G 1 25  ? -12.626  11.963  12.344  1.00 78.58  ? 232 LEU G C   1 
ATOM   9049  O O   . LEU G 1 25  ? -11.539  12.519  12.161  1.00 83.54  ? 232 LEU G O   1 
ATOM   9050  C CB  . LEU G 1 25  ? -12.344  10.359  14.291  1.00 70.84  ? 232 LEU G CB  1 
ATOM   9051  C CG  . LEU G 1 25  ? -12.480  10.108  15.789  1.00 67.79  ? 232 LEU G CG  1 
ATOM   9052  C CD1 . LEU G 1 25  ? -11.582  8.964   16.213  1.00 71.67  ? 232 LEU G CD1 1 
ATOM   9053  C CD2 . LEU G 1 25  ? -12.156  11.361  16.586  1.00 61.74  ? 232 LEU G CD2 1 
ATOM   9054  N N   . PHE G 1 26  ? -13.446  11.620  11.355  1.00 78.47  ? 233 PHE G N   1 
ATOM   9055  C CA  . PHE G 1 26  ? -13.133  12.040  9.964   1.00 80.75  ? 233 PHE G CA  1 
ATOM   9056  C C   . PHE G 1 26  ? -13.370  13.541  9.828   1.00 77.84  ? 233 PHE G C   1 
ATOM   9057  O O   . PHE G 1 26  ? -12.579  14.213  9.159   1.00 81.40  ? 233 PHE G O   1 
ATOM   9058  C CB  . PHE G 1 26  ? -13.966  11.191  9.005   1.00 83.85  ? 233 PHE G CB  1 
ATOM   9059  C CG  . PHE G 1 26  ? -14.198  11.689  7.606   1.00 86.07  ? 233 PHE G CG  1 
ATOM   9060  C CD1 . PHE G 1 26  ? -13.301  11.396  6.597   1.00 85.32  ? 233 PHE G CD1 1 
ATOM   9061  C CD2 . PHE G 1 26  ? -15.361  12.367  7.283   1.00 84.04  ? 233 PHE G CD2 1 
ATOM   9062  C CE1 . PHE G 1 26  ? -13.536  11.825  5.303   1.00 85.08  ? 233 PHE G CE1 1 
ATOM   9063  C CE2 . PHE G 1 26  ? -15.593  12.796  5.989   1.00 84.71  ? 233 PHE G CE2 1 
ATOM   9064  C CZ  . PHE G 1 26  ? -14.676  12.529  5.003   1.00 87.43  ? 233 PHE G CZ  1 
ATOM   9065  N N   . PHE G 1 27  ? -14.428  14.038  10.460  1.00 74.08  ? 234 PHE G N   1 
ATOM   9066  C CA  . PHE G 1 27  ? -14.774  15.477  10.352  1.00 76.99  ? 234 PHE G CA  1 
ATOM   9067  C C   . PHE G 1 27  ? -13.813  16.301  11.208  1.00 74.40  ? 234 PHE G C   1 
ATOM   9068  O O   . PHE G 1 27  ? -13.917  17.531  11.186  1.00 73.41  ? 234 PHE G O   1 
ATOM   9069  C CB  . PHE G 1 27  ? -16.263  15.668  10.635  1.00 78.50  ? 234 PHE G CB  1 
ATOM   9070  C CG  . PHE G 1 27  ? -17.141  15.259  9.482   1.00 78.84  ? 234 PHE G CG  1 
ATOM   9071  C CD1 . PHE G 1 27  ? -16.899  15.741  8.207   1.00 78.12  ? 234 PHE G CD1 1 
ATOM   9072  C CD2 . PHE G 1 27  ? -18.190  14.375  9.661   1.00 78.92  ? 234 PHE G CD2 1 
ATOM   9073  C CE1 . PHE G 1 27  ? -17.704  15.366  7.144   1.00 80.77  ? 234 PHE G CE1 1 
ATOM   9074  C CE2 . PHE G 1 27  ? -18.991  13.994  8.597   1.00 82.84  ? 234 PHE G CE2 1 
ATOM   9075  C CZ  . PHE G 1 27  ? -18.745  14.490  7.339   1.00 81.54  ? 234 PHE G CZ  1 
ATOM   9076  N N   . THR G 1 28  ? -12.955  15.644  11.986  1.00 81.06  ? 235 THR G N   1 
ATOM   9077  C CA  . THR G 1 28  ? -11.877  16.395  12.673  1.00 80.45  ? 235 THR G CA  1 
ATOM   9078  C C   . THR G 1 28  ? -10.788  16.430  11.608  1.00 86.56  ? 235 THR G C   1 
ATOM   9079  O O   . THR G 1 28  ? -9.844   15.639  11.711  1.00 82.53  ? 235 THR G O   1 
ATOM   9080  C CB  . THR G 1 28  ? -11.489  15.801  14.033  1.00 78.79  ? 235 THR G CB  1 
ATOM   9081  O OG1 . THR G 1 28  ? -11.036  14.456  13.897  1.00 87.80  ? 235 THR G OG1 1 
ATOM   9082  C CG2 . THR G 1 28  ? -12.623  15.842  15.034  1.00 77.84  ? 235 THR G CG2 1 
ATOM   9083  N N   . ASN G 1 29  ? -10.966  17.276  10.594  1.00 88.04  ? 236 ASN G N   1 
ATOM   9084  C CA  . ASN G 1 29  ? -10.049  17.321  9.426   1.00 85.36  ? 236 ASN G CA  1 
ATOM   9085  C C   . ASN G 1 29  ? -8.571   17.339  9.824   1.00 84.77  ? 236 ASN G C   1 
ATOM   9086  O O   . ASN G 1 29  ? -7.785   16.728  9.105   1.00 80.96  ? 236 ASN G O   1 
ATOM   9087  C CB  . ASN G 1 29  ? -10.384  18.511  8.535   1.00 88.65  ? 236 ASN G CB  1 
ATOM   9088  C CG  . ASN G 1 29  ? -11.835  18.549  8.107   1.00 92.80  ? 236 ASN G CG  1 
ATOM   9089  O OD1 . ASN G 1 29  ? -12.705  18.963  8.868   1.00 91.59  ? 236 ASN G OD1 1 
ATOM   9090  N ND2 . ASN G 1 29  ? -12.101  18.137  6.881   1.00 84.21  ? 236 ASN G ND2 1 
ATOM   9091  N N   . GLN G 1 30  ? -8.210   18.059  10.882  1.00 81.47  ? 237 GLN G N   1 
ATOM   9092  C CA  . GLN G 1 30  ? -6.786   18.136  11.280  1.00 81.96  ? 237 GLN G CA  1 
ATOM   9093  C C   . GLN G 1 30  ? -6.301   16.719  11.575  1.00 85.01  ? 237 GLN G C   1 
ATOM   9094  O O   . GLN G 1 30  ? -5.227   16.355  11.066  1.00 83.61  ? 237 GLN G O   1 
ATOM   9095  C CB  . GLN G 1 30  ? -6.586   19.054  12.481  1.00 79.16  ? 237 GLN G CB  1 
ATOM   9096  C CG  . GLN G 1 30  ? -5.389   19.978  12.317  1.00 76.78  ? 237 GLN G CG  1 
ATOM   9097  C CD  . GLN G 1 30  ? -4.977   20.648  13.604  1.00 81.77  ? 237 GLN G CD  1 
ATOM   9098  O OE1 . GLN G 1 30  ? -5.707   21.456  14.169  1.00 79.99  ? 237 GLN G OE1 1 
ATOM   9099  N NE2 . GLN G 1 30  ? -3.788   20.315  14.075  1.00 83.48  ? 237 GLN G NE2 1 
ATOM   9100  N N   . LEU G 1 31  ? -7.064   15.958  12.360  1.00 79.96  ? 238 LEU G N   1 
ATOM   9101  C CA  . LEU G 1 31  ? -6.700   14.544  12.611  1.00 82.72  ? 238 LEU G CA  1 
ATOM   9102  C C   . LEU G 1 31  ? -6.728   13.801  11.277  1.00 81.37  ? 238 LEU G C   1 
ATOM   9103  O O   . LEU G 1 31  ? -5.765   13.101  10.989  1.00 77.59  ? 238 LEU G O   1 
ATOM   9104  C CB  . LEU G 1 31  ? -7.690   13.933  13.605  1.00 81.76  ? 238 LEU G CB  1 
ATOM   9105  C CG  . LEU G 1 31  ? -7.484   12.452  13.910  1.00 82.39  ? 238 LEU G CG  1 
ATOM   9106  C CD1 . LEU G 1 31  ? -6.091   12.208  14.463  1.00 72.10  ? 238 LEU G CD1 1 
ATOM   9107  C CD2 . LEU G 1 31  ? -8.538   11.951  14.881  1.00 76.72  ? 238 LEU G CD2 1 
ATOM   9108  N N   . ARG G 1 32  ? -7.788   13.976  10.492  1.00 80.51  ? 239 ARG G N   1 
ATOM   9109  C CA  . ARG G 1 32  ? -7.900   13.254  9.229   1.00 75.69  ? 239 ARG G CA  1 
ATOM   9110  C C   . ARG G 1 32  ? -6.669   13.473  8.356   1.00 84.04  ? 239 ARG G C   1 
ATOM   9111  O O   . ARG G 1 32  ? -6.141   12.525  7.755   1.00 79.05  ? 239 ARG G O   1 
ATOM   9112  C CB  . ARG G 1 32  ? -9.167   13.695  8.504   1.00 76.64  ? 239 ARG G CB  1 
ATOM   9113  C CG  . ARG G 1 32  ? -9.518   12.818  7.322   1.00 79.32  ? 239 ARG G CG  1 
ATOM   9114  C CD  . ARG G 1 32  ? -10.172  13.609  6.215   1.00 81.36  ? 239 ARG G CD  1 
ATOM   9115  N NE  . ARG G 1 32  ? -11.424  14.225  6.634   1.00 77.49  ? 239 ARG G NE  1 
ATOM   9116  C CZ  . ARG G 1 32  ? -12.254  14.836  5.800   1.00 80.12  ? 239 ARG G CZ  1 
ATOM   9117  N NH1 . ARG G 1 32  ? -11.965  14.900  4.504   1.00 85.79  ? 239 ARG G NH1 1 
ATOM   9118  N NH2 . ARG G 1 32  ? -13.377  15.367  6.256   1.00 82.18  ? 239 ARG G NH2 1 
ATOM   9119  N N   . LYS G 1 33  ? -6.184   14.724  8.293   1.00 89.74  ? 240 LYS G N   1 
ATOM   9120  C CA  . LYS G 1 33  ? -4.970   15.029  7.536   1.00 83.23  ? 240 LYS G CA  1 
ATOM   9121  C C   . LYS G 1 33  ? -3.750   14.358  8.160   1.00 82.24  ? 240 LYS G C   1 
ATOM   9122  O O   . LYS G 1 33  ? -2.916   13.783  7.448   1.00 81.94  ? 240 LYS G O   1 
ATOM   9123  C CB  . LYS G 1 33  ? -4.779   16.548  7.444   1.00 81.98  ? 240 LYS G CB  1 
ATOM   9124  N N   . ALA G 1 34  ? -3.636   14.409  9.489   1.00 83.03  ? 241 ALA G N   1 
ATOM   9125  C CA  . ALA G 1 34  ? -2.551   13.704  10.158  1.00 82.54  ? 241 ALA G CA  1 
ATOM   9126  C C   . ALA G 1 34  ? -2.531   12.222  9.798   1.00 84.33  ? 241 ALA G C   1 
ATOM   9127  O O   . ALA G 1 34  ? -1.456   11.606  9.765   1.00 84.86  ? 241 ALA G O   1 
ATOM   9128  C CB  . ALA G 1 34  ? -2.674   13.889  11.666  1.00 79.37  ? 241 ALA G CB  1 
ATOM   9129  N N   . VAL G 1 35  ? -3.695   11.640  9.495   1.00 80.87  ? 242 VAL G N   1 
ATOM   9130  C CA  . VAL G 1 35  ? -3.782   10.194  9.301   1.00 85.47  ? 242 VAL G CA  1 
ATOM   9131  C C   . VAL G 1 35  ? -3.265   9.792   7.924   1.00 84.90  ? 242 VAL G C   1 
ATOM   9132  O O   . VAL G 1 35  ? -2.487   8.840   7.795   1.00 83.96  ? 242 VAL G O   1 
ATOM   9133  C CB  . VAL G 1 35  ? -5.228   9.702   9.531   1.00 87.09  ? 242 VAL G CB  1 
ATOM   9134  C CG1 . VAL G 1 35  ? -5.379   8.227   9.129   1.00 85.94  ? 242 VAL G CG1 1 
ATOM   9135  C CG2 . VAL G 1 35  ? -5.635   9.891   10.987  1.00 83.52  ? 242 VAL G CG2 1 
ATOM   9136  N N   . TYR G 1 36  ? -3.701   10.490  6.869   1.00 86.20  ? 243 TYR G N   1 
ATOM   9137  C CA  . TYR G 1 36  ? -3.188   10.185  5.533   1.00 85.98  ? 243 TYR G CA  1 
ATOM   9138  C C   . TYR G 1 36  ? -1.664   10.246  5.490   1.00 84.51  ? 243 TYR G C   1 
ATOM   9139  O O   . TYR G 1 36  ? -1.027   9.481   4.759   1.00 76.25  ? 243 TYR G O   1 
ATOM   9140  C CB  . TYR G 1 36  ? -3.755   11.160  4.502   1.00 85.33  ? 243 TYR G CB  1 
ATOM   9141  C CG  . TYR G 1 36  ? -5.264   11.172  4.342   1.00 80.28  ? 243 TYR G CG  1 
ATOM   9142  C CD1 . TYR G 1 36  ? -5.957   10.025  3.961   1.00 77.06  ? 243 TYR G CD1 1 
ATOM   9143  C CD2 . TYR G 1 36  ? -5.988   12.347  4.528   1.00 74.90  ? 243 TYR G CD2 1 
ATOM   9144  C CE1 . TYR G 1 36  ? -7.337   10.044  3.797   1.00 80.25  ? 243 TYR G CE1 1 
ATOM   9145  C CE2 . TYR G 1 36  ? -7.364   12.379  4.364   1.00 77.26  ? 243 TYR G CE2 1 
ATOM   9146  C CZ  . TYR G 1 36  ? -8.035   11.226  3.998   1.00 82.36  ? 243 TYR G CZ  1 
ATOM   9147  O OH  . TYR G 1 36  ? -9.399   11.259  3.830   1.00 82.53  ? 243 TYR G OH  1 
ATOM   9148  N N   . MET G 1 37  ? -1.065   11.137  6.284   1.00 90.64  ? 244 MET G N   1 
ATOM   9149  C CA  . MET G 1 37  ? 0.375    11.336  6.314   1.00 87.38  ? 244 MET G CA  1 
ATOM   9150  C C   . MET G 1 37  ? 1.127    10.215  7.033   1.00 89.57  ? 244 MET G C   1 
ATOM   9151  O O   . MET G 1 37  ? 2.356    10.144  6.910   1.00 90.45  ? 244 MET G O   1 
ATOM   9152  C CB  . MET G 1 37  ? 0.676    12.692  6.969   1.00 88.02  ? 244 MET G CB  1 
ATOM   9153  N N   . MET G 1 38  ? 0.437    9.345   7.768   1.00 92.14  ? 245 MET G N   1 
ATOM   9154  C CA  . MET G 1 38  ? 1.127    8.319   8.544   1.00 90.20  ? 245 MET G CA  1 
ATOM   9155  C C   . MET G 1 38  ? 1.948    7.423   7.617   1.00 92.59  ? 245 MET G C   1 
ATOM   9156  O O   . MET G 1 38  ? 1.490    7.072   6.520   1.00 89.39  ? 245 MET G O   1 
ATOM   9157  C CB  . MET G 1 38  ? 0.129    7.487   9.355   1.00 85.60  ? 245 MET G CB  1 
ATOM   9158  C CG  . MET G 1 38  ? -0.736   8.322   10.298  1.00 86.90  ? 245 MET G CG  1 
ATOM   9159  S SD  . MET G 1 38  ? -1.390   7.454   11.752  1.00 85.94  ? 245 MET G SD  1 
ATOM   9160  C CE  . MET G 1 38  ? -0.046   6.298   12.111  1.00 87.60  ? 245 MET G CE  1 
ATOM   9161  N N   . PRO G 1 39  ? 3.194    7.011   8.032   1.00 92.62  ? 246 PRO G N   1 
ATOM   9162  C CA  . PRO G 1 39  ? 4.103    6.256   7.158   1.00 90.43  ? 246 PRO G CA  1 
ATOM   9163  C C   . PRO G 1 39  ? 3.656    4.819   6.899   1.00 92.82  ? 246 PRO G C   1 
ATOM   9164  O O   . PRO G 1 39  ? 4.392    3.892   7.177   1.00 91.65  ? 246 PRO G O   1 
ATOM   9165  C CB  . PRO G 1 39  ? 5.448    6.262   7.895   1.00 84.03  ? 246 PRO G CB  1 
ATOM   9166  C CG  . PRO G 1 39  ? 5.064    6.245   9.335   1.00 89.84  ? 246 PRO G CG  1 
ATOM   9167  C CD  . PRO G 1 39  ? 3.873    7.170   9.358   1.00 91.02  ? 246 PRO G CD  1 
ATOM   9168  N N   . THR G 1 40  ? 2.460    4.677   6.356   1.00 93.53  ? 247 THR G N   1 
ATOM   9169  C CA  . THR G 1 40  ? 1.987    3.364   5.972   1.00 92.89  ? 247 THR G CA  1 
ATOM   9170  C C   . THR G 1 40  ? 2.780    2.929   4.735   1.00 95.13  ? 247 THR G C   1 
ATOM   9171  O O   . THR G 1 40  ? 2.519    1.888   4.129   1.00 102.64 ? 247 THR G O   1 
ATOM   9172  C CB  . THR G 1 40  ? 0.475    3.378   5.682   1.00 93.74  ? 247 THR G CB  1 
ATOM   9173  O OG1 . THR G 1 40  ? 0.250    3.991   4.411   1.00 100.82 ? 247 THR G OG1 1 
ATOM   9174  C CG2 . THR G 1 40  ? -0.276   4.181   6.740   1.00 88.11  ? 247 THR G CG2 1 
ATOM   9175  N N   . SER G 1 46  ? -4.278   -5.601  5.531   1.00 96.17  ? 253 SER G N   1 
ATOM   9176  C CA  . SER G 1 46  ? -4.986   -4.816  6.576   1.00 101.96 ? 253 SER G CA  1 
ATOM   9177  C C   . SER G 1 46  ? -4.543   -5.253  7.975   1.00 101.05 ? 253 SER G C   1 
ATOM   9178  O O   . SER G 1 46  ? -5.412   -5.650  8.770   1.00 98.20  ? 253 SER G O   1 
ATOM   9179  C CB  . SER G 1 46  ? -6.486   -4.903  6.411   1.00 93.84  ? 253 SER G CB  1 
ATOM   9180  O OG  . SER G 1 46  ? -6.950   -6.236  6.567   1.00 94.47  ? 253 SER G OG  1 
ATOM   9181  N N   . LYS G 1 47  ? -3.241   -5.184  8.274   1.00 97.29  ? 254 LYS G N   1 
ATOM   9182  C CA  . LYS G 1 47  ? -2.839   -5.488  9.648   1.00 93.73  ? 254 LYS G CA  1 
ATOM   9183  C C   . LYS G 1 47  ? -2.615   -4.244  10.500  1.00 90.71  ? 254 LYS G C   1 
ATOM   9184  O O   . LYS G 1 47  ? -2.319   -4.375  11.689  1.00 92.68  ? 254 LYS G O   1 
ATOM   9185  C CB  . LYS G 1 47  ? -1.565   -6.343  9.649   1.00 90.73  ? 254 LYS G CB  1 
ATOM   9186  N N   . SER G 1 48  ? -2.781   -3.049  9.932   1.00 87.79  ? 255 SER G N   1 
ATOM   9187  C CA  . SER G 1 48  ? -2.514   -1.790  10.615  1.00 83.99  ? 255 SER G CA  1 
ATOM   9188  C C   . SER G 1 48  ? -3.803   -0.993  10.773  1.00 88.87  ? 255 SER G C   1 
ATOM   9189  O O   . SER G 1 48  ? -4.527   -0.766  9.790   1.00 91.75  ? 255 SER G O   1 
ATOM   9190  C CB  . SER G 1 48  ? -1.477   -0.973  9.842   1.00 75.25  ? 255 SER G CB  1 
ATOM   9191  N N   . VAL G 1 49  ? -4.098   -0.577  12.006  1.00 81.67  ? 256 VAL G N   1 
ATOM   9192  C CA  . VAL G 1 49  ? -5.201   0.354   12.231  1.00 81.29  ? 256 VAL G CA  1 
ATOM   9193  C C   . VAL G 1 49  ? -5.018   1.642   11.431  1.00 82.84  ? 256 VAL G C   1 
ATOM   9194  O O   . VAL G 1 49  ? -5.998   2.130   10.856  1.00 79.80  ? 256 VAL G O   1 
ATOM   9195  C CB  . VAL G 1 49  ? -5.399   0.598   13.725  1.00 81.21  ? 256 VAL G CB  1 
ATOM   9196  C CG1 . VAL G 1 49  ? -6.367   1.736   13.956  1.00 76.10  ? 256 VAL G CG1 1 
ATOM   9197  C CG2 . VAL G 1 49  ? -5.903   -0.676  14.409  1.00 82.15  ? 256 VAL G CG2 1 
ATOM   9198  N N   . PRO G 1 50  ? -3.828   2.247   11.359  1.00 84.85  ? 257 PRO G N   1 
ATOM   9199  C CA  . PRO G 1 50  ? -3.714   3.468   10.543  1.00 81.44  ? 257 PRO G CA  1 
ATOM   9200  C C   . PRO G 1 50  ? -3.981   3.206   9.073   1.00 84.32  ? 257 PRO G C   1 
ATOM   9201  O O   . PRO G 1 50  ? -4.729   3.958   8.431   1.00 78.85  ? 257 PRO G O   1 
ATOM   9202  C CB  . PRO G 1 50  ? -2.270   3.914   10.804  1.00 82.64  ? 257 PRO G CB  1 
ATOM   9203  C CG  . PRO G 1 50  ? -1.863   3.220   12.064  1.00 81.14  ? 257 PRO G CG  1 
ATOM   9204  C CD  . PRO G 1 50  ? -2.542   1.915   12.000  1.00 81.54  ? 257 PRO G CD  1 
ATOM   9205  N N   . LEU G 1 51  ? -3.381   2.146   8.522   1.00 84.76  ? 258 LEU G N   1 
ATOM   9206  C CA  . LEU G 1 51  ? -3.586   1.825   7.115   1.00 84.38  ? 258 LEU G CA  1 
ATOM   9207  C C   . LEU G 1 51  ? -5.067   1.643   6.811   1.00 83.52  ? 258 LEU G C   1 
ATOM   9208  O O   . LEU G 1 51  ? -5.590   2.207   5.843   1.00 83.13  ? 258 LEU G O   1 
ATOM   9209  C CB  . LEU G 1 51  ? -2.792   0.570   6.746   1.00 74.51  ? 258 LEU G CB  1 
ATOM   9210  N N   . ALA G 1 52  ? -5.766   0.872   7.645   1.00 83.99  ? 259 ALA G N   1 
ATOM   9211  C CA  . ALA G 1 52  ? -7.207   0.713   7.463   1.00 87.29  ? 259 ALA G CA  1 
ATOM   9212  C C   . ALA G 1 52  ? -7.964   2.009   7.743   1.00 85.34  ? 259 ALA G C   1 
ATOM   9213  O O   . ALA G 1 52  ? -8.994   2.275   7.111   1.00 79.60  ? 259 ALA G O   1 
ATOM   9214  C CB  . ALA G 1 52  ? -7.723   -0.412  8.360   1.00 84.68  ? 259 ALA G CB  1 
ATOM   9215  N N   . LEU G 1 53  ? -7.474   2.816   8.688   1.00 88.45  ? 260 LEU G N   1 
ATOM   9216  C CA  . LEU G 1 53  ? -8.091   4.106   8.972   1.00 84.45  ? 260 LEU G CA  1 
ATOM   9217  C C   . LEU G 1 53  ? -7.911   5.064   7.807   1.00 84.35  ? 260 LEU G C   1 
ATOM   9218  O O   . LEU G 1 53  ? -8.805   5.861   7.503   1.00 83.34  ? 260 LEU G O   1 
ATOM   9219  C CB  . LEU G 1 53  ? -7.487   4.702   10.240  1.00 83.81  ? 260 LEU G CB  1 
ATOM   9220  C CG  . LEU G 1 53  ? -8.365   4.662   11.478  1.00 83.28  ? 260 LEU G CG  1 
ATOM   9221  C CD1 . LEU G 1 53  ? -7.637   5.309   12.637  1.00 85.53  ? 260 LEU G CD1 1 
ATOM   9222  C CD2 . LEU G 1 53  ? -9.683   5.371   11.190  1.00 90.03  ? 260 LEU G CD2 1 
ATOM   9223  N N   . GLN G 1 54  ? -6.743   5.019   7.168   1.00 85.95  ? 261 GLN G N   1 
ATOM   9224  C CA  . GLN G 1 54  ? -6.526   5.813   5.966   1.00 87.10  ? 261 GLN G CA  1 
ATOM   9225  C C   . GLN G 1 54  ? -7.515   5.413   4.883   1.00 80.30  ? 261 GLN G C   1 
ATOM   9226  O O   . GLN G 1 54  ? -8.146   6.268   4.249   1.00 78.47  ? 261 GLN G O   1 
ATOM   9227  C CB  . GLN G 1 54  ? -5.080   5.640   5.483   1.00 84.17  ? 261 GLN G CB  1 
ATOM   9228  N N   . ARG G 1 55  ? -7.681   4.106   4.684   1.00 81.17  ? 262 ARG G N   1 
ATOM   9229  C CA  . ARG G 1 55  ? -8.579   3.610   3.649   1.00 83.96  ? 262 ARG G CA  1 
ATOM   9230  C C   . ARG G 1 55  ? -10.003  4.106   3.874   1.00 88.59  ? 262 ARG G C   1 
ATOM   9231  O O   . ARG G 1 55  ? -10.650  4.613   2.951   1.00 91.15  ? 262 ARG G O   1 
ATOM   9232  C CB  . ARG G 1 55  ? -8.528   2.080   3.609   1.00 79.42  ? 262 ARG G CB  1 
ATOM   9233  N N   . VAL G 1 56  ? -10.501  3.979   5.105   1.00 87.95  ? 263 VAL G N   1 
ATOM   9234  C CA  . VAL G 1 56  ? -11.854  4.427   5.416   1.00 82.59  ? 263 VAL G CA  1 
ATOM   9235  C C   . VAL G 1 56  ? -11.952  5.940   5.308   1.00 85.84  ? 263 VAL G C   1 
ATOM   9236  O O   . VAL G 1 56  ? -12.894  6.477   4.711   1.00 87.42  ? 263 VAL G O   1 
ATOM   9237  C CB  . VAL G 1 56  ? -12.264  3.932   6.813   1.00 84.93  ? 263 VAL G CB  1 
ATOM   9238  C CG1 . VAL G 1 56  ? -13.396  4.790   7.393   1.00 74.33  ? 263 VAL G CG1 1 
ATOM   9239  C CG2 . VAL G 1 56  ? -12.646  2.468   6.738   1.00 81.89  ? 263 VAL G CG2 1 
ATOM   9240  N N   . PHE G 1 57  ? -10.976  6.648   5.883   1.00 86.22  ? 264 PHE G N   1 
ATOM   9241  C CA  . PHE G 1 57  ? -10.988  8.105   5.859   1.00 85.10  ? 264 PHE G CA  1 
ATOM   9242  C C   . PHE G 1 57  ? -10.955  8.654   4.436   1.00 93.25  ? 264 PHE G C   1 
ATOM   9243  O O   . PHE G 1 57  ? -11.427  9.773   4.198   1.00 92.49  ? 264 PHE G O   1 
ATOM   9244  C CB  . PHE G 1 57  ? -9.808   8.639   6.668   1.00 88.15  ? 264 PHE G CB  1 
ATOM   9245  C CG  . PHE G 1 57  ? -10.130  8.892   8.111   1.00 88.68  ? 264 PHE G CG  1 
ATOM   9246  C CD1 . PHE G 1 57  ? -11.256  8.341   8.693   1.00 89.47  ? 264 PHE G CD1 1 
ATOM   9247  C CD2 . PHE G 1 57  ? -9.311   9.687   8.886   1.00 82.69  ? 264 PHE G CD2 1 
ATOM   9248  C CE1 . PHE G 1 57  ? -11.557  8.585   10.024  1.00 84.54  ? 264 PHE G CE1 1 
ATOM   9249  C CE2 . PHE G 1 57  ? -9.611   9.932   10.203  1.00 80.78  ? 264 PHE G CE2 1 
ATOM   9250  C CZ  . PHE G 1 57  ? -10.730  9.380   10.773  1.00 82.94  ? 264 PHE G CZ  1 
ATOM   9251  N N   . TYR G 1 58  ? -10.471  7.874   3.475   1.00 90.95  ? 265 TYR G N   1 
ATOM   9252  C CA  . TYR G 1 58  ? -10.462  8.350   2.071   1.00 89.30  ? 265 TYR G CA  1 
ATOM   9253  C C   . TYR G 1 58  ? -11.828  8.165   1.424   1.00 87.56  ? 265 TYR G C   1 
ATOM   9254  O O   . TYR G 1 58  ? -12.326  9.121   0.832   1.00 87.39  ? 265 TYR G O   1 
ATOM   9255  C CB  . TYR G 1 58  ? -9.431   7.588   1.241   1.00 95.22  ? 265 TYR G CB  1 
ATOM   9256  C CG  . TYR G 1 58  ? -9.365   8.020   -0.201  1.00 104.80 ? 265 TYR G CG  1 
ATOM   9257  C CD1 . TYR G 1 58  ? -9.136   9.344   -0.539  1.00 104.60 ? 265 TYR G CD1 1 
ATOM   9258  C CD2 . TYR G 1 58  ? -9.548   7.112   -1.230  1.00 107.49 ? 265 TYR G CD2 1 
ATOM   9259  C CE1 . TYR G 1 58  ? -9.087   9.754   -1.860  1.00 102.39 ? 265 TYR G CE1 1 
ATOM   9260  C CE2 . TYR G 1 58  ? -9.498   7.504   -2.556  1.00 103.29 ? 265 TYR G CE2 1 
ATOM   9261  C CZ  . TYR G 1 58  ? -9.266   8.830   -2.872  1.00 110.56 ? 265 TYR G CZ  1 
ATOM   9262  O OH  . TYR G 1 58  ? -9.214   9.226   -4.177  1.00 117.19 ? 265 TYR G OH  1 
ATOM   9263  N N   . GLU G 1 59  ? -12.388  6.963   1.510   1.00 88.42  ? 266 GLU G N   1 
ATOM   9264  C CA  . GLU G 1 59  ? -13.644  6.668   0.828   1.00 87.43  ? 266 GLU G CA  1 
ATOM   9265  C C   . GLU G 1 59  ? -14.815  7.456   1.401   1.00 87.82  ? 266 GLU G C   1 
ATOM   9266  O O   . GLU G 1 59  ? -15.852  7.575   0.741   1.00 85.18  ? 266 GLU G O   1 
ATOM   9267  C CB  . GLU G 1 59  ? -13.928  5.164   0.894   1.00 85.64  ? 266 GLU G CB  1 
ATOM   9268  N N   . LEU G 1 60  ? -14.672  7.998   2.607   1.00 87.29  ? 267 LEU G N   1 
ATOM   9269  C CA  . LEU G 1 60  ? -15.656  8.933   3.129   1.00 89.25  ? 267 LEU G CA  1 
ATOM   9270  C C   . LEU G 1 60  ? -15.522  10.332  2.515   1.00 90.58  ? 267 LEU G C   1 
ATOM   9271  O O   . LEU G 1 60  ? -16.486  11.113  2.557   1.00 84.57  ? 267 LEU G O   1 
ATOM   9272  C CB  . LEU G 1 60  ? -15.542  8.991   4.658   1.00 89.94  ? 267 LEU G CB  1 
ATOM   9273  N N   . GLN G 1 61  ? -14.356  10.665  1.945   1.00 93.80  ? 268 GLN G N   1 
ATOM   9274  C CA  . GLN G 1 61  ? -14.147  11.900  1.192   1.00 90.91  ? 268 GLN G CA  1 
ATOM   9275  C C   . GLN G 1 61  ? -14.136  11.662  -0.312  1.00 85.52  ? 268 GLN G C   1 
ATOM   9276  O O   . GLN G 1 61  ? -13.652  12.510  -1.066  1.00 86.77  ? 268 GLN G O   1 
ATOM   9277  C CB  . GLN G 1 61  ? -12.840  12.577  1.615   1.00 92.61  ? 268 GLN G CB  1 
ATOM   9278  N N   . HIS G 1 62  ? -14.655  10.523  -0.756  1.00 86.94  ? 269 HIS G N   1 
ATOM   9279  C CA  . HIS G 1 62  ? -14.620  10.129  -2.154  1.00 88.63  ? 269 HIS G CA  1 
ATOM   9280  C C   . HIS G 1 62  ? -15.552  8.940   -2.378  1.00 90.81  ? 269 HIS G C   1 
ATOM   9281  O O   . HIS G 1 62  ? -16.762  9.115   -2.560  1.00 94.62  ? 269 HIS G O   1 
ATOM   9282  C CB  . HIS G 1 62  ? -13.190  9.781   -2.584  1.00 93.00  ? 269 HIS G CB  1 
ATOM   9283  N N   . ASP G 1 64  ? -19.281  7.796   -3.206  1.00 94.89  ? 271 ASP G N   1 
ATOM   9284  C CA  . ASP G 1 64  ? -20.663  8.127   -3.537  1.00 93.48  ? 271 ASP G CA  1 
ATOM   9285  C C   . ASP G 1 64  ? -21.612  6.991   -3.170  1.00 91.48  ? 271 ASP G C   1 
ATOM   9286  O O   . ASP G 1 64  ? -22.823  7.118   -3.342  1.00 85.95  ? 271 ASP G O   1 
ATOM   9287  C CB  . ASP G 1 64  ? -20.797  8.458   -5.024  1.00 88.82  ? 271 ASP G CB  1 
ATOM   9288  N N   . LYS G 1 65  ? -21.054  5.884   -2.674  1.00 97.51  ? 272 LYS G N   1 
ATOM   9289  C CA  . LYS G 1 65  ? -21.848  4.757   -2.174  1.00 94.07  ? 272 LYS G CA  1 
ATOM   9290  C C   . LYS G 1 65  ? -21.376  4.328   -0.785  1.00 93.84  ? 272 LYS G C   1 
ATOM   9291  O O   . LYS G 1 65  ? -20.228  4.565   -0.411  1.00 91.50  ? 272 LYS G O   1 
ATOM   9292  C CB  . LYS G 1 65  ? -21.783  3.567   -3.140  1.00 86.83  ? 272 LYS G CB  1 
ATOM   9293  N N   . VAL G 1 67  ? -19.610  3.144   2.660   1.00 84.57  ? 274 VAL G N   1 
ATOM   9294  C CA  . VAL G 1 67  ? -18.184  2.823   2.959   1.00 87.11  ? 274 VAL G CA  1 
ATOM   9295  C C   . VAL G 1 67  ? -18.126  1.536   3.783   1.00 87.56  ? 274 VAL G C   1 
ATOM   9296  O O   . VAL G 1 67  ? -18.798  1.469   4.822   1.00 81.67  ? 274 VAL G O   1 
ATOM   9297  C CB  . VAL G 1 67  ? -17.481  3.996   3.665   1.00 87.55  ? 274 VAL G CB  1 
ATOM   9298  C CG1 . VAL G 1 67  ? -16.026  3.691   3.981   1.00 82.13  ? 274 VAL G CG1 1 
ATOM   9299  C CG2 . VAL G 1 67  ? -17.591  5.277   2.859   1.00 81.09  ? 274 VAL G CG2 1 
ATOM   9300  N N   . GLY G 1 68  ? -17.338  0.560   3.330   1.00 95.24  ? 275 GLY G N   1 
ATOM   9301  C CA  . GLY G 1 68  ? -17.244  -0.719  4.009   1.00 89.90  ? 275 GLY G CA  1 
ATOM   9302  C C   . GLY G 1 68  ? -16.118  -0.820  5.017   1.00 91.51  ? 275 GLY G C   1 
ATOM   9303  O O   . GLY G 1 68  ? -14.937  -0.855  4.649   1.00 90.32  ? 275 GLY G O   1 
ATOM   9304  N N   . THR G 1 69  ? -16.490  -0.895  6.300   1.00 91.88  ? 276 THR G N   1 
ATOM   9305  C CA  . THR G 1 69  ? -15.581  -0.947  7.445   1.00 88.07  ? 276 THR G CA  1 
ATOM   9306  C C   . THR G 1 69  ? -14.871  -2.295  7.609   1.00 85.45  ? 276 THR G C   1 
ATOM   9307  O O   . THR G 1 69  ? -14.087  -2.440  8.551   1.00 84.71  ? 276 THR G O   1 
ATOM   9308  C CB  . THR G 1 69  ? -16.348  -0.627  8.750   1.00 87.81  ? 276 THR G CB  1 
ATOM   9309  O OG1 . THR G 1 69  ? -17.187  -1.732  9.122   1.00 85.89  ? 276 THR G OG1 1 
ATOM   9310  C CG2 . THR G 1 69  ? -17.218  0.616   8.615   1.00 83.18  ? 276 THR G CG2 1 
ATOM   9311  N N   . LYS G 1 70  ? -15.103  -3.272  6.730   1.00 83.89  ? 277 LYS G N   1 
ATOM   9312  C CA  . LYS G 1 70  ? -14.712  -4.644  7.033   1.00 83.45  ? 277 LYS G CA  1 
ATOM   9313  C C   . LYS G 1 70  ? -13.213  -4.785  7.306   1.00 83.70  ? 277 LYS G C   1 
ATOM   9314  O O   . LYS G 1 70  ? -12.810  -5.627  8.120   1.00 84.10  ? 277 LYS G O   1 
ATOM   9315  C CB  . LYS G 1 70  ? -15.150  -5.567  5.896   1.00 84.31  ? 277 LYS G CB  1 
ATOM   9316  N N   . LYS G 1 71  ? -12.371  -3.979  6.656   1.00 82.87  ? 278 LYS G N   1 
ATOM   9317  C CA  . LYS G 1 71  ? -10.929  -4.088  6.874   1.00 87.12  ? 278 LYS G CA  1 
ATOM   9318  C C   . LYS G 1 71  ? -10.481  -3.478  8.202   1.00 88.44  ? 278 LYS G C   1 
ATOM   9319  O O   . LYS G 1 71  ? -9.413   -3.851  8.711   1.00 84.86  ? 278 LYS G O   1 
ATOM   9320  C CB  . LYS G 1 71  ? -10.171  -3.435  5.711   1.00 83.65  ? 278 LYS G CB  1 
ATOM   9321  N N   . LEU G 1 72  ? -11.259  -2.551  8.765   1.00 85.92  ? 279 LEU G N   1 
ATOM   9322  C CA  . LEU G 1 72  ? -10.869  -1.874  10.031  1.00 80.69  ? 279 LEU G CA  1 
ATOM   9323  C C   . LEU G 1 72  ? -11.089  -2.822  11.205  1.00 82.47  ? 279 LEU G C   1 
ATOM   9324  O O   . LEU G 1 72  ? -10.210  -2.927  12.042  1.00 79.50  ? 279 LEU G O   1 
ATOM   9325  C CB  . LEU G 1 72  ? -11.708  -0.609  10.205  1.00 76.66  ? 279 LEU G CB  1 
ATOM   9326  C CG  . LEU G 1 72  ? -11.256  0.349   11.303  1.00 75.90  ? 279 LEU G CG  1 
ATOM   9327  C CD1 . LEU G 1 72  ? -9.809   0.766   11.114  1.00 78.54  ? 279 LEU G CD1 1 
ATOM   9328  C CD2 . LEU G 1 72  ? -12.153  1.568   11.353  1.00 70.47  ? 279 LEU G CD2 1 
ATOM   9329  N N   . THR G 1 73  ? -12.240  -3.482  11.250  1.00 83.15  ? 280 THR G N   1 
ATOM   9330  C CA  . THR G 1 73  ? -12.547  -4.409  12.364  1.00 78.26  ? 280 THR G CA  1 
ATOM   9331  C C   . THR G 1 73  ? -11.562  -5.573  12.325  1.00 83.14  ? 280 THR G C   1 
ATOM   9332  O O   . THR G 1 73  ? -11.214  -6.079  13.396  1.00 83.29  ? 280 THR G O   1 
ATOM   9333  C CB  . THR G 1 73  ? -14.005  -4.864  12.308  1.00 75.72  ? 280 THR G CB  1 
ATOM   9334  O OG1 . THR G 1 73  ? -14.342  -5.127  10.946  1.00 80.23  ? 280 THR G OG1 1 
ATOM   9335  C CG2 . THR G 1 73  ? -14.951  -3.842  12.896  1.00 73.66  ? 280 THR G CG2 1 
ATOM   9336  N N   . LYS G 1 74  ? -11.134  -5.977  11.134  1.00 84.93  ? 281 LYS G N   1 
ATOM   9337  C CA  . LYS G 1 74  ? -10.111  -7.042  11.037  1.00 83.49  ? 281 LYS G CA  1 
ATOM   9338  C C   . LYS G 1 74  ? -8.771   -6.446  11.442  1.00 83.67  ? 281 LYS G C   1 
ATOM   9339  O O   . LYS G 1 74  ? -7.957   -7.189  11.996  1.00 83.49  ? 281 LYS G O   1 
ATOM   9340  C CB  . LYS G 1 74  ? -10.052  -7.605  9.619   1.00 84.00  ? 281 LYS G CB  1 
ATOM   9341  N N   . SER G 1 75  ? -8.534   -5.172  11.126  1.00 85.07  ? 282 SER G N   1 
ATOM   9342  C CA  . SER G 1 75  ? -7.285   -4.535  11.611  1.00 85.50  ? 282 SER G CA  1 
ATOM   9343  C C   . SER G 1 75  ? -7.303   -4.603  13.133  1.00 86.19  ? 282 SER G C   1 
ATOM   9344  O O   . SER G 1 75  ? -6.217   -4.667  13.721  1.00 88.70  ? 282 SER G O   1 
ATOM   9345  C CB  . SER G 1 75  ? -7.110   -3.130  11.097  1.00 84.93  ? 282 SER G CB  1 
ATOM   9346  O OG  . SER G 1 75  ? -7.645   -2.168  11.987  1.00 79.03  ? 282 SER G OG  1 
ATOM   9347  N N   . PHE G 1 76  ? -8.483   -4.654  13.747  1.00 86.21  ? 283 PHE G N   1 
ATOM   9348  C CA  . PHE G 1 76  ? -8.567   -4.790  15.222  1.00 83.11  ? 283 PHE G CA  1 
ATOM   9349  C C   . PHE G 1 76  ? -8.311   -6.244  15.636  1.00 86.92  ? 283 PHE G C   1 
ATOM   9350  O O   . PHE G 1 76  ? -8.339   -6.506  16.847  1.00 84.79  ? 283 PHE G O   1 
ATOM   9351  C CB  . PHE G 1 76  ? -9.931   -4.336  15.740  1.00 79.69  ? 283 PHE G CB  1 
ATOM   9352  C CG  . PHE G 1 76  ? -10.325  -2.908  15.466  1.00 78.22  ? 283 PHE G CG  1 
ATOM   9353  C CD1 . PHE G 1 76  ? -9.377   -1.932  15.210  1.00 81.04  ? 283 PHE G CD1 1 
ATOM   9354  C CD2 . PHE G 1 76  ? -11.658  -2.538  15.489  1.00 79.35  ? 283 PHE G CD2 1 
ATOM   9355  C CE1 . PHE G 1 76  ? -9.756   -0.623  14.961  1.00 82.73  ? 283 PHE G CE1 1 
ATOM   9356  C CE2 . PHE G 1 76  ? -12.035  -1.229  15.244  1.00 78.75  ? 283 PHE G CE2 1 
ATOM   9357  C CZ  . PHE G 1 76  ? -11.084  -0.273  14.984  1.00 77.59  ? 283 PHE G CZ  1 
ATOM   9358  N N   . GLY G 1 77  ? -8.058   -7.151  14.683  1.00 88.91  ? 284 GLY G N   1 
ATOM   9359  C CA  . GLY G 1 77  ? -7.880   -8.550  15.036  1.00 88.40  ? 284 GLY G CA  1 
ATOM   9360  C C   . GLY G 1 77  ? -9.156   -9.297  15.368  1.00 82.52  ? 284 GLY G C   1 
ATOM   9361  O O   . GLY G 1 77  ? -9.105   -10.335 16.037  1.00 83.22  ? 284 GLY G O   1 
ATOM   9362  N N   . TRP G 1 78  ? -10.282  -8.793  14.881  1.00 82.26  ? 285 TRP G N   1 
ATOM   9363  C CA  . TRP G 1 78  ? -11.588  -9.399  15.223  1.00 83.18  ? 285 TRP G CA  1 
ATOM   9364  C C   . TRP G 1 78  ? -12.081  -10.314 14.100  1.00 84.47  ? 285 TRP G C   1 
ATOM   9365  O O   . TRP G 1 78  ? -11.579  -10.191 12.973  1.00 82.64  ? 285 TRP G O   1 
ATOM   9366  C CB  . TRP G 1 78  ? -12.601  -8.280  15.444  1.00 81.67  ? 285 TRP G CB  1 
ATOM   9367  C CG  . TRP G 1 78  ? -12.390  -7.383  16.620  1.00 82.64  ? 285 TRP G CG  1 
ATOM   9368  C CD1 . TRP G 1 78  ? -11.432  -7.463  17.586  1.00 87.45  ? 285 TRP G CD1 1 
ATOM   9369  C CD2 . TRP G 1 78  ? -13.204  -6.249  16.954  1.00 81.88  ? 285 TRP G CD2 1 
ATOM   9370  N NE1 . TRP G 1 78  ? -11.588  -6.449  18.492  1.00 87.67  ? 285 TRP G NE1 1 
ATOM   9371  C CE2 . TRP G 1 78  ? -12.669  -5.689  18.131  1.00 82.47  ? 285 TRP G CE2 1 
ATOM   9372  C CE3 . TRP G 1 78  ? -14.327  -5.656  16.372  1.00 76.11  ? 285 TRP G CE3 1 
ATOM   9373  C CZ2 . TRP G 1 78  ? -13.222  -4.561  18.731  1.00 78.38  ? 285 TRP G CZ2 1 
ATOM   9374  C CZ3 . TRP G 1 78  ? -14.872  -4.541  16.966  1.00 74.11  ? 285 TRP G CZ3 1 
ATOM   9375  C CH2 . TRP G 1 78  ? -14.326  -4.004  18.130  1.00 69.00  ? 285 TRP G CH2 1 
ATOM   9376  N N   . GLU G 1 79  ? -13.044  -11.189 14.396  1.00 85.56  ? 286 GLU G N   1 
ATOM   9377  C CA  . GLU G 1 79  ? -13.676  -12.027 13.347  1.00 81.77  ? 286 GLU G CA  1 
ATOM   9378  C C   . GLU G 1 79  ? -15.044  -11.424 13.021  1.00 83.47  ? 286 GLU G C   1 
ATOM   9379  O O   . GLU G 1 79  ? -15.268  -10.240 13.345  1.00 88.59  ? 286 GLU G O   1 
ATOM   9380  C CB  . GLU G 1 79  ? -13.819  -13.470 13.821  1.00 79.50  ? 286 GLU G CB  1 
ATOM   9381  N N   . THR G 1 80  ? -15.935  -12.204 12.419  1.00 79.69  ? 287 THR G N   1 
ATOM   9382  C CA  . THR G 1 80  ? -17.237  -11.634 11.984  1.00 79.42  ? 287 THR G CA  1 
ATOM   9383  C C   . THR G 1 80  ? -18.155  -11.447 13.191  1.00 82.21  ? 287 THR G C   1 
ATOM   9384  O O   . THR G 1 80  ? -18.804  -10.407 13.263  1.00 81.32  ? 287 THR G O   1 
ATOM   9385  C CB  . THR G 1 80  ? -17.878  -12.502 10.900  1.00 77.87  ? 287 THR G CB  1 
ATOM   9386  O OG1 . THR G 1 80  ? -16.856  -12.927 9.997   1.00 82.57  ? 287 THR G OG1 1 
ATOM   9387  C CG2 . THR G 1 80  ? -18.957  -11.780 10.124  1.00 70.36  ? 287 THR G CG2 1 
ATOM   9388  N N   . LEU G 1 81  ? -18.178  -12.410 14.107  1.00 88.76  ? 288 LEU G N   1 
ATOM   9389  C CA  . LEU G 1 81  ? -19.064  -12.345 15.298  1.00 86.88  ? 288 LEU G CA  1 
ATOM   9390  C C   . LEU G 1 81  ? -18.698  -11.135 16.147  1.00 83.40  ? 288 LEU G C   1 
ATOM   9391  O O   . LEU G 1 81  ? -19.597  -10.561 16.767  1.00 80.09  ? 288 LEU G O   1 
ATOM   9392  C CB  . LEU G 1 81  ? -18.865  -13.627 16.106  1.00 91.15  ? 288 LEU G CB  1 
ATOM   9393  C CG  . LEU G 1 81  ? -20.127  -14.260 16.681  1.00 102.86 ? 288 LEU G CG  1 
ATOM   9394  C CD1 . LEU G 1 81  ? -21.318  -14.072 15.754  1.00 99.68  ? 288 LEU G CD1 1 
ATOM   9395  C CD2 . LEU G 1 81  ? -19.891  -15.732 16.952  1.00 106.00 ? 288 LEU G CD2 1 
ATOM   9396  N N   . ASP G 1 82  ? -17.413  -10.801 16.197  1.00 83.27  ? 289 ASP G N   1 
ATOM   9397  C CA  . ASP G 1 82  ? -16.950  -9.653  17.008  1.00 76.20  ? 289 ASP G CA  1 
ATOM   9398  C C   . ASP G 1 82  ? -17.610  -8.380  16.474  1.00 75.53  ? 289 ASP G C   1 
ATOM   9399  O O   . ASP G 1 82  ? -17.608  -7.377  17.195  1.00 76.01  ? 289 ASP G O   1 
ATOM   9400  C CB  . ASP G 1 82  ? -15.426  -9.602  17.025  1.00 74.86  ? 289 ASP G CB  1 
ATOM   9401  C CG  . ASP G 1 82  ? -14.768  -10.864 17.546  1.00 83.68  ? 289 ASP G CG  1 
ATOM   9402  O OD1 . ASP G 1 82  ? -14.816  -11.883 16.838  1.00 83.82  ? 289 ASP G OD1 1 
ATOM   9403  O OD2 . ASP G 1 82  ? -14.202  -10.811 18.652  1.00 87.04  ? 289 ASP G OD2 1 
ATOM   9404  N N   . SER G 1 83  ? -18.172  -8.434  15.268  1.00 74.73  ? 290 SER G N   1 
ATOM   9405  C CA  . SER G 1 83  ? -18.811  -7.254  14.709  1.00 74.75  ? 290 SER G CA  1 
ATOM   9406  C C   . SER G 1 83  ? -20.326  -7.277  14.869  1.00 80.17  ? 290 SER G C   1 
ATOM   9407  O O   . SER G 1 83  ? -21.013  -6.416  14.300  1.00 76.70  ? 290 SER G O   1 
ATOM   9408  C CB  . SER G 1 83  ? -18.433  -7.102  13.239  1.00 72.81  ? 290 SER G CB  1 
ATOM   9409  O OG  . SER G 1 83  ? -17.087  -7.504  13.043  1.00 78.19  ? 290 SER G OG  1 
ATOM   9410  N N   . PHE G 1 84  ? -20.861  -8.235  15.635  1.00 77.18  ? 291 PHE G N   1 
ATOM   9411  C CA  . PHE G 1 84  ? -22.261  -8.230  16.049  1.00 74.43  ? 291 PHE G CA  1 
ATOM   9412  C C   . PHE G 1 84  ? -22.398  -7.945  17.537  1.00 72.12  ? 291 PHE G C   1 
ATOM   9413  O O   . PHE G 1 84  ? -23.432  -8.263  18.140  1.00 67.25  ? 291 PHE G O   1 
ATOM   9414  C CB  . PHE G 1 84  ? -22.941  -9.552  15.692  1.00 69.78  ? 291 PHE G CB  1 
ATOM   9415  C CG  . PHE G 1 84  ? -23.056  -9.789  14.218  1.00 70.00  ? 291 PHE G CG  1 
ATOM   9416  C CD1 . PHE G 1 84  ? -21.979  -10.287 13.501  1.00 76.12  ? 291 PHE G CD1 1 
ATOM   9417  C CD2 . PHE G 1 84  ? -24.239  -9.510  13.544  1.00 70.76  ? 291 PHE G CD2 1 
ATOM   9418  C CE1 . PHE G 1 84  ? -22.073  -10.508 12.133  1.00 76.43  ? 291 PHE G CE1 1 
ATOM   9419  C CE2 . PHE G 1 84  ? -24.346  -9.723  12.175  1.00 72.77  ? 291 PHE G CE2 1 
ATOM   9420  C CZ  . PHE G 1 84  ? -23.255  -10.225 11.469  1.00 74.90  ? 291 PHE G CZ  1 
ATOM   9421  N N   . MET G 1 85  ? -21.358  -7.361  18.134  1.00 70.65  ? 292 MET G N   1 
ATOM   9422  C CA  . MET G 1 85  ? -21.322  -7.014  19.546  1.00 68.93  ? 292 MET G CA  1 
ATOM   9423  C C   . MET G 1 85  ? -21.587  -5.520  19.695  1.00 61.49  ? 292 MET G C   1 
ATOM   9424  O O   . MET G 1 85  ? -21.001  -4.703  18.978  1.00 67.19  ? 292 MET G O   1 
ATOM   9425  C CB  . MET G 1 85  ? -19.971  -7.400  20.157  1.00 65.45  ? 292 MET G CB  1 
ATOM   9426  C CG  . MET G 1 85  ? -20.066  -8.059  21.539  1.00 74.20  ? 292 MET G CG  1 
ATOM   9427  S SD  . MET G 1 85  ? -20.603  -9.801  21.535  1.00 73.34  ? 292 MET G SD  1 
ATOM   9428  C CE  . MET G 1 85  ? -21.477  -9.873  23.106  1.00 71.67  ? 292 MET G CE  1 
ATOM   9429  N N   . GLN G 1 86  ? -22.491  -5.172  20.599  1.00 59.61  ? 293 GLN G N   1 
ATOM   9430  C CA  . GLN G 1 86  ? -22.809  -3.778  20.845  1.00 65.52  ? 293 GLN G CA  1 
ATOM   9431  C C   . GLN G 1 86  ? -21.798  -3.194  21.828  1.00 67.28  ? 293 GLN G C   1 
ATOM   9432  O O   . GLN G 1 86  ? -21.227  -3.902  22.660  1.00 67.80  ? 293 GLN G O   1 
ATOM   9433  C CB  . GLN G 1 86  ? -24.246  -3.644  21.366  1.00 63.63  ? 293 GLN G CB  1 
ATOM   9434  N N   . HIS G 1 87  ? -21.489  -1.925  21.614  1.00 65.25  ? 294 HIS G N   1 
ATOM   9435  C CA  . HIS G 1 87  ? -20.389  -1.374  22.424  1.00 63.81  ? 294 HIS G CA  1 
ATOM   9436  C C   . HIS G 1 87  ? -20.571  0.090   22.782  1.00 65.10  ? 294 HIS G C   1 
ATOM   9437  O O   . HIS G 1 87  ? -21.351  0.776   22.118  1.00 67.38  ? 294 HIS G O   1 
ATOM   9438  C CB  . HIS G 1 87  ? -19.069  -1.539  21.667  1.00 67.34  ? 294 HIS G CB  1 
ATOM   9439  C CG  . HIS G 1 87  ? -18.392  -2.854  21.844  1.00 62.84  ? 294 HIS G CG  1 
ATOM   9440  N ND1 . HIS G 1 87  ? -18.299  -3.772  20.825  1.00 55.11  ? 294 HIS G ND1 1 
ATOM   9441  C CD2 . HIS G 1 87  ? -17.769  -3.401  22.907  1.00 58.94  ? 294 HIS G CD2 1 
ATOM   9442  C CE1 . HIS G 1 87  ? -17.648  -4.831  21.249  1.00 52.11  ? 294 HIS G CE1 1 
ATOM   9443  N NE2 . HIS G 1 87  ? -17.317  -4.630  22.523  1.00 59.64  ? 294 HIS G NE2 1 
ATOM   9444  N N   . ASP G 1 88  ? -19.847  0.512   23.822  1.00 63.13  ? 295 ASP G N   1 
ATOM   9445  C CA  . ASP G 1 88  ? -19.859  1.923   24.265  1.00 58.97  ? 295 ASP G CA  1 
ATOM   9446  C C   . ASP G 1 88  ? -19.010  2.735   23.303  1.00 61.92  ? 295 ASP G C   1 
ATOM   9447  O O   . ASP G 1 88  ? -17.851  2.363   23.066  1.00 58.46  ? 295 ASP G O   1 
ATOM   9448  C CB  . ASP G 1 88  ? -19.305  2.067   25.681  1.00 60.68  ? 295 ASP G CB  1 
ATOM   9449  C CG  . ASP G 1 88  ? -19.447  3.450   26.276  1.00 62.21  ? 295 ASP G CG  1 
ATOM   9450  O OD1 . ASP G 1 88  ? -18.431  4.133   26.405  1.00 59.51  ? 295 ASP G OD1 1 
ATOM   9451  O OD2 . ASP G 1 88  ? -20.569  3.813   26.620  1.00 62.75  ? 295 ASP G OD2 1 
ATOM   9452  N N   . VAL G 1 89  ? -19.582  3.812   22.789  1.00 62.87  ? 296 VAL G N   1 
ATOM   9453  C CA  . VAL G 1 89  ? -18.868  4.680   21.858  1.00 65.01  ? 296 VAL G CA  1 
ATOM   9454  C C   . VAL G 1 89  ? -17.621  5.262   22.523  1.00 61.05  ? 296 VAL G C   1 
ATOM   9455  O O   . VAL G 1 89  ? -16.523  5.258   21.947  1.00 60.11  ? 296 VAL G O   1 
ATOM   9456  C CB  . VAL G 1 89  ? -19.828  5.771   21.318  1.00 64.90  ? 296 VAL G CB  1 
ATOM   9457  C CG1 . VAL G 1 89  ? -19.924  7.023   22.237  1.00 58.05  ? 296 VAL G CG1 1 
ATOM   9458  C CG2 . VAL G 1 89  ? -19.452  6.165   19.897  1.00 67.15  ? 296 VAL G CG2 1 
ATOM   9459  N N   . GLN G 1 90  ? -17.754  5.696   23.774  1.00 57.05  ? 297 GLN G N   1 
ATOM   9460  C CA  . GLN G 1 90  ? -16.666  6.409   24.426  1.00 62.18  ? 297 GLN G CA  1 
ATOM   9461  C C   . GLN G 1 90  ? -15.550  5.453   24.831  1.00 60.25  ? 297 GLN G C   1 
ATOM   9462  O O   . GLN G 1 90  ? -14.386  5.852   24.894  1.00 58.81  ? 297 GLN G O   1 
ATOM   9463  C CB  . GLN G 1 90  ? -17.228  7.193   25.615  1.00 57.92  ? 297 GLN G CB  1 
ATOM   9464  C CG  . GLN G 1 90  ? -16.264  8.124   26.243  1.00 52.45  ? 297 GLN G CG  1 
ATOM   9465  C CD  . GLN G 1 90  ? -15.488  7.438   27.311  1.00 55.16  ? 297 GLN G CD  1 
ATOM   9466  O OE1 . GLN G 1 90  ? -15.750  6.284   27.619  1.00 56.41  ? 297 GLN G OE1 1 
ATOM   9467  N NE2 . GLN G 1 90  ? -14.531  8.134   27.898  1.00 61.88  ? 297 GLN G NE2 1 
ATOM   9468  N N   . GLU G 1 91  ? -15.874  4.184   25.079  1.00 57.49  ? 298 GLU G N   1 
ATOM   9469  C CA  . GLU G 1 91  ? -14.807  3.215   25.274  1.00 57.06  ? 298 GLU G CA  1 
ATOM   9470  C C   . GLU G 1 91  ? -14.035  3.014   23.988  1.00 56.16  ? 298 GLU G C   1 
ATOM   9471  O O   . GLU G 1 91  ? -12.809  2.860   24.011  1.00 56.31  ? 298 GLU G O   1 
ATOM   9472  C CB  . GLU G 1 91  ? -15.361  1.887   25.774  1.00 54.79  ? 298 GLU G CB  1 
ATOM   9473  C CG  . GLU G 1 91  ? -14.274  0.859   26.028  1.00 52.98  ? 298 GLU G CG  1 
ATOM   9474  C CD  . GLU G 1 91  ? -14.819  -0.447  26.557  1.00 53.03  ? 298 GLU G CD  1 
ATOM   9475  O OE1 . GLU G 1 91  ? -14.014  -1.318  26.923  1.00 50.10  ? 298 GLU G OE1 1 
ATOM   9476  O OE2 . GLU G 1 91  ? -16.057  -0.596  26.607  1.00 55.84  ? 298 GLU G OE2 1 
ATOM   9477  N N   . LEU G 1 92  ? -14.734  3.034   22.851  1.00 57.59  ? 299 LEU G N   1 
ATOM   9478  C CA  . LEU G 1 92  ? -14.041  2.864   21.585  1.00 61.03  ? 299 LEU G CA  1 
ATOM   9479  C C   . LEU G 1 92  ? -13.100  4.035   21.314  1.00 64.69  ? 299 LEU G C   1 
ATOM   9480  O O   . LEU G 1 92  ? -11.968  3.844   20.846  1.00 57.92  ? 299 LEU G O   1 
ATOM   9481  C CB  . LEU G 1 92  ? -15.042  2.704   20.448  1.00 54.79  ? 299 LEU G CB  1 
ATOM   9482  C CG  . LEU G 1 92  ? -14.294  2.526   19.120  1.00 60.31  ? 299 LEU G CG  1 
ATOM   9483  C CD1 . LEU G 1 92  ? -13.390  1.289   19.131  1.00 59.34  ? 299 LEU G CD1 1 
ATOM   9484  C CD2 . LEU G 1 92  ? -15.249  2.490   17.960  1.00 67.62  ? 299 LEU G CD2 1 
ATOM   9485  N N   . CYS G 1 93  ? -13.540  5.253   21.615  1.00 60.21  ? 300 CYS G N   1 
ATOM   9486  C CA  . CYS G 1 93  ? -12.684  6.451   21.411  1.00 62.21  ? 300 CYS G CA  1 
ATOM   9487  C C   . CYS G 1 93  ? -11.351  6.256   22.122  1.00 60.20  ? 300 CYS G C   1 
ATOM   9488  O O   . CYS G 1 93  ? -10.324  6.323   21.455  1.00 56.13  ? 300 CYS G O   1 
ATOM   9489  C CB  . CYS G 1 93  ? -13.354  7.697   21.972  1.00 64.39  ? 300 CYS G CB  1 
ATOM   9490  S SG  . CYS G 1 93  ? -12.767  9.240   21.238  1.00 61.41  ? 300 CYS G SG  1 
ATOM   9491  N N   . ARG G 1 94  ? -11.388  6.026   23.431  1.00 62.08  ? 301 ARG G N   1 
ATOM   9492  C CA  . ARG G 1 94  ? -10.145  5.883   24.223  1.00 57.74  ? 301 ARG G CA  1 
ATOM   9493  C C   . ARG G 1 94  ? -9.266   4.787   23.631  1.00 60.55  ? 301 ARG G C   1 
ATOM   9494  O O   . ARG G 1 94  ? -8.092   5.057   23.406  1.00 60.38  ? 301 ARG G O   1 
ATOM   9495  C CB  . ARG G 1 94  ? -10.491  5.607   25.688  1.00 53.88  ? 301 ARG G CB  1 
ATOM   9496  C CG  . ARG G 1 94  ? -11.441  6.618   26.312  1.00 59.61  ? 301 ARG G CG  1 
ATOM   9497  C CD  . ARG G 1 94  ? -10.808  7.879   26.873  1.00 56.95  ? 301 ARG G CD  1 
ATOM   9498  N NE  . ARG G 1 94  ? -9.865   8.553   25.988  1.00 65.38  ? 301 ARG G NE  1 
ATOM   9499  C CZ  . ARG G 1 94  ? -10.179  9.340   24.964  1.00 64.31  ? 301 ARG G CZ  1 
ATOM   9500  N NH1 . ARG G 1 94  ? -11.440  9.596   24.668  1.00 64.64  ? 301 ARG G NH1 1 
ATOM   9501  N NH2 . ARG G 1 94  ? -9.219   9.865   24.228  1.00 64.01  ? 301 ARG G NH2 1 
ATOM   9502  N N   . VAL G 1 95  ? -9.824   3.604   23.400  1.00 53.60  ? 302 VAL G N   1 
ATOM   9503  C CA  . VAL G 1 95  ? -8.997   2.526   22.870  1.00 59.57  ? 302 VAL G CA  1 
ATOM   9504  C C   . VAL G 1 95  ? -8.401   2.922   21.516  1.00 62.37  ? 302 VAL G C   1 
ATOM   9505  O O   . VAL G 1 95  ? -7.203   2.739   21.275  1.00 64.82  ? 302 VAL G O   1 
ATOM   9506  C CB  . VAL G 1 95  ? -9.784   1.200   22.805  1.00 58.94  ? 302 VAL G CB  1 
ATOM   9507  C CG1 . VAL G 1 95  ? -10.785  1.188   21.657  1.00 65.34  ? 302 VAL G CG1 1 
ATOM   9508  C CG2 . VAL G 1 95  ? -8.810   0.032   22.663  1.00 58.81  ? 302 VAL G CG2 1 
ATOM   9509  N N   . LEU G 1 96  ? -9.207   3.525   20.638  1.00 61.88  ? 303 LEU G N   1 
ATOM   9510  C CA  . LEU G 1 96  ? -8.750   3.800   19.279  1.00 62.93  ? 303 LEU G CA  1 
ATOM   9511  C C   . LEU G 1 96  ? -7.754   4.963   19.226  1.00 70.15  ? 303 LEU G C   1 
ATOM   9512  O O   . LEU G 1 96  ? -6.712   4.867   18.563  1.00 68.66  ? 303 LEU G O   1 
ATOM   9513  C CB  . LEU G 1 96  ? -9.947   4.084   18.376  1.00 62.55  ? 303 LEU G CB  1 
ATOM   9514  C CG  . LEU G 1 96  ? -9.627   4.706   17.015  1.00 64.72  ? 303 LEU G CG  1 
ATOM   9515  C CD1 . LEU G 1 96  ? -8.927   3.691   16.095  1.00 61.02  ? 303 LEU G CD1 1 
ATOM   9516  C CD2 . LEU G 1 96  ? -10.900  5.288   16.371  1.00 58.89  ? 303 LEU G CD2 1 
ATOM   9517  N N   . LEU G 1 97  ? -8.073   6.091   19.875  1.00 64.88  ? 304 LEU G N   1 
ATOM   9518  C CA  . LEU G 1 97  ? -7.147   7.224   19.861  1.00 67.32  ? 304 LEU G CA  1 
ATOM   9519  C C   . LEU G 1 97  ? -5.828   6.868   20.536  1.00 69.76  ? 304 LEU G C   1 
ATOM   9520  O O   . LEU G 1 97  ? -4.764   7.346   20.126  1.00 71.53  ? 304 LEU G O   1 
ATOM   9521  C CB  . LEU G 1 97  ? -7.764   8.443   20.545  1.00 64.75  ? 304 LEU G CB  1 
ATOM   9522  C CG  . LEU G 1 97  ? -8.920   9.153   19.856  1.00 66.74  ? 304 LEU G CG  1 
ATOM   9523  C CD1 . LEU G 1 97  ? -9.327   10.409  20.658  1.00 66.42  ? 304 LEU G CD1 1 
ATOM   9524  C CD2 . LEU G 1 97  ? -8.555   9.476   18.410  1.00 61.91  ? 304 LEU G CD2 1 
ATOM   9525  N N   . ASP G 1 98  ? -5.875   6.047   21.591  1.00 65.81  ? 305 ASP G N   1 
ATOM   9526  C CA  . ASP G 1 98  ? -4.633   5.659   22.243  1.00 66.95  ? 305 ASP G CA  1 
ATOM   9527  C C   . ASP G 1 98  ? -3.768   4.817   21.317  1.00 70.13  ? 305 ASP G C   1 
ATOM   9528  O O   . ASP G 1 98  ? -2.535   4.867   21.393  1.00 69.75  ? 305 ASP G O   1 
ATOM   9529  C CB  . ASP G 1 98  ? -4.922   4.900   23.533  1.00 65.19  ? 305 ASP G CB  1 
ATOM   9530  C CG  . ASP G 1 98  ? -3.656   4.458   24.233  1.00 71.25  ? 305 ASP G CG  1 
ATOM   9531  O OD1 . ASP G 1 98  ? -2.989   5.312   24.869  1.00 76.79  ? 305 ASP G OD1 1 
ATOM   9532  O OD2 . ASP G 1 98  ? -3.315   3.261   24.128  1.00 70.11  ? 305 ASP G OD2 1 
ATOM   9533  N N   . ASN G 1 99  ? -4.402   4.057   20.426  1.00 71.06  ? 306 ASN G N   1 
ATOM   9534  C CA  . ASN G 1 99  ? -3.675   3.207   19.491  1.00 73.08  ? 306 ASN G CA  1 
ATOM   9535  C C   . ASN G 1 99  ? -3.013   4.032   18.381  1.00 76.16  ? 306 ASN G C   1 
ATOM   9536  O O   . ASN G 1 99  ? -1.848   3.799   18.032  1.00 71.52  ? 306 ASN G O   1 
ATOM   9537  C CB  . ASN G 1 99  ? -4.657   2.178   18.931  1.00 70.84  ? 306 ASN G CB  1 
ATOM   9538  C CG  . ASN G 1 99  ? -4.015   1.184   18.011  1.00 77.97  ? 306 ASN G CG  1 
ATOM   9539  O OD1 . ASN G 1 99  ? -3.699   1.507   16.866  1.00 85.03  ? 306 ASN G OD1 1 
ATOM   9540  N ND2 . ASN G 1 99  ? -3.848   -0.049  18.485  1.00 75.72  ? 306 ASN G ND2 1 
ATOM   9541  N N   . VAL G 1 100 ? -3.735   5.024   17.844  1.00 73.62  ? 307 VAL G N   1 
ATOM   9542  C CA  . VAL G 1 100 ? -3.245   5.821   16.722  1.00 71.60  ? 307 VAL G CA  1 
ATOM   9543  C C   . VAL G 1 100 ? -2.168   6.803   17.177  1.00 73.22  ? 307 VAL G C   1 
ATOM   9544  O O   . VAL G 1 100 ? -1.232   7.105   16.426  1.00 72.92  ? 307 VAL G O   1 
ATOM   9545  C CB  . VAL G 1 100 ? -4.431   6.539   16.043  1.00 72.25  ? 307 VAL G CB  1 
ATOM   9546  C CG1 . VAL G 1 100 ? -3.953   7.456   14.932  1.00 76.98  ? 307 VAL G CG1 1 
ATOM   9547  C CG2 . VAL G 1 100 ? -5.430   5.532   15.505  1.00 64.48  ? 307 VAL G CG2 1 
ATOM   9548  N N   . GLU G 1 101 ? -2.283   7.323   18.405  1.00 71.58  ? 308 GLU G N   1 
ATOM   9549  C CA  . GLU G 1 101 ? -1.256   8.219   18.937  1.00 71.91  ? 308 GLU G CA  1 
ATOM   9550  C C   . GLU G 1 101 ? 0.060    7.484   19.160  1.00 73.40  ? 308 GLU G C   1 
ATOM   9551  O O   . GLU G 1 101 ? 1.143    8.034   18.940  1.00 76.52  ? 308 GLU G O   1 
ATOM   9552  C CB  . GLU G 1 101 ? -1.729   8.859   20.244  1.00 69.77  ? 308 GLU G CB  1 
ATOM   9553  C CG  . GLU G 1 101 ? -0.615   9.547   21.023  1.00 75.58  ? 308 GLU G CG  1 
ATOM   9554  C CD  . GLU G 1 101 ? -1.020   9.971   22.431  1.00 74.05  ? 308 GLU G CD  1 
ATOM   9555  O OE1 . GLU G 1 101 ? -0.182   9.841   23.361  1.00 75.09  ? 308 GLU G OE1 1 
ATOM   9556  O OE2 . GLU G 1 101 ? -2.166   10.443  22.605  1.00 66.12  ? 308 GLU G OE2 1 
ATOM   9557  N N   . ASN G 1 102 ? -0.007   6.245   19.616  1.00 75.71  ? 309 ASN G N   1 
ATOM   9558  C CA  . ASN G 1 102 ? 1.217    5.471   19.694  1.00 76.46  ? 309 ASN G CA  1 
ATOM   9559  C C   . ASN G 1 102 ? 1.706    5.089   18.308  1.00 79.53  ? 309 ASN G C   1 
ATOM   9560  O O   . ASN G 1 102 ? 2.917    4.945   18.092  1.00 87.73  ? 309 ASN G O   1 
ATOM   9561  C CB  . ASN G 1 102 ? 0.997    4.228   20.550  1.00 77.31  ? 309 ASN G CB  1 
ATOM   9562  C CG  . ASN G 1 102 ? 1.167    4.509   22.021  1.00 84.30  ? 309 ASN G CG  1 
ATOM   9563  O OD1 . ASN G 1 102 ? 2.184    4.145   22.614  1.00 94.27  ? 309 ASN G OD1 1 
ATOM   9564  N ND2 . ASN G 1 102 ? 0.180    5.177   22.621  1.00 80.62  ? 309 ASN G ND2 1 
ATOM   9565  N N   . LYS G 1 103 ? 0.787    4.914   17.358  1.00 76.21  ? 310 LYS G N   1 
ATOM   9566  C CA  . LYS G 1 103 ? 1.218    4.605   16.002  1.00 77.15  ? 310 LYS G CA  1 
ATOM   9567  C C   . LYS G 1 103 ? 1.929    5.801   15.383  1.00 79.30  ? 310 LYS G C   1 
ATOM   9568  O O   . LYS G 1 103 ? 2.847    5.623   14.575  1.00 82.77  ? 310 LYS G O   1 
ATOM   9569  C CB  . LYS G 1 103 ? 0.026    4.161   15.147  1.00 72.19  ? 310 LYS G CB  1 
ATOM   9570  N N   . MET G 1 104 ? 1.560    7.015   15.784  1.00 72.59  ? 311 MET G N   1 
ATOM   9571  C CA  . MET G 1 104 ? 2.163    8.225   15.247  1.00 73.41  ? 311 MET G CA  1 
ATOM   9572  C C   . MET G 1 104 ? 3.483    8.602   15.913  1.00 73.80  ? 311 MET G C   1 
ATOM   9573  O O   . MET G 1 104 ? 3.977    9.707   15.666  1.00 72.20  ? 311 MET G O   1 
ATOM   9574  C CB  . MET G 1 104 ? 1.190    9.391   15.378  1.00 70.75  ? 311 MET G CB  1 
ATOM   9575  C CG  . MET G 1 104 ? 0.021    9.274   14.462  1.00 71.59  ? 311 MET G CG  1 
ATOM   9576  S SD  . MET G 1 104 ? -1.043   10.684  14.701  1.00 80.35  ? 311 MET G SD  1 
ATOM   9577  C CE  . MET G 1 104 ? -2.319   10.333  13.487  1.00 78.55  ? 311 MET G CE  1 
ATOM   9578  N N   . LYS G 1 105 ? 4.078    7.727   16.723  1.00 72.90  ? 312 LYS G N   1 
ATOM   9579  C CA  . LYS G 1 105 ? 5.271    8.079   17.488  1.00 75.61  ? 312 LYS G CA  1 
ATOM   9580  C C   . LYS G 1 105 ? 6.523    7.820   16.658  1.00 81.76  ? 312 LYS G C   1 
ATOM   9581  O O   . LYS G 1 105 ? 6.684    6.741   16.078  1.00 89.56  ? 312 LYS G O   1 
ATOM   9582  C CB  . LYS G 1 105 ? 5.332    7.297   18.802  1.00 76.76  ? 312 LYS G CB  1 
ATOM   9583  N N   . GLY G 1 106 ? 7.410    8.807   16.608  1.00 80.61  ? 313 GLY G N   1 
ATOM   9584  C CA  . GLY G 1 106 ? 8.560    8.704   15.743  1.00 80.25  ? 313 GLY G CA  1 
ATOM   9585  C C   . GLY G 1 106 ? 8.257    9.007   14.299  1.00 86.23  ? 313 GLY G C   1 
ATOM   9586  O O   . GLY G 1 106 ? 9.013    8.578   13.423  1.00 90.05  ? 313 GLY G O   1 
ATOM   9587  N N   . THR G 1 107 ? 7.150    9.729   14.084  1.00 85.52  ? 314 THR G N   1 
ATOM   9588  C CA  . THR G 1 107 ? 6.698    10.091  12.718  1.00 87.67  ? 314 THR G CA  1 
ATOM   9589  C C   . THR G 1 107 ? 6.545    11.609  12.591  1.00 85.35  ? 314 THR G C   1 
ATOM   9590  O O   . THR G 1 107 ? 6.766    12.317  13.587  1.00 80.44  ? 314 THR G O   1 
ATOM   9591  C CB  . THR G 1 107 ? 5.370    9.407   12.361  1.00 83.89  ? 314 THR G CB  1 
ATOM   9592  O OG1 . THR G 1 107 ? 4.283    10.138  12.931  1.00 75.78  ? 314 THR G OG1 1 
ATOM   9593  C CG2 . THR G 1 107 ? 5.300    7.961   12.802  1.00 76.36  ? 314 THR G CG2 1 
ATOM   9594  N N   . CYS G 1 108 ? 6.137    12.087  11.411  1.00 88.07  ? 315 CYS G N   1 
ATOM   9595  C CA  . CYS G 1 108 ? 6.019    13.544  11.134  1.00 82.31  ? 315 CYS G CA  1 
ATOM   9596  C C   . CYS G 1 108 ? 4.806    14.147  11.833  1.00 86.96  ? 315 CYS G C   1 
ATOM   9597  O O   . CYS G 1 108 ? 4.754    15.381  11.944  1.00 85.99  ? 315 CYS G O   1 
ATOM   9598  C CB  . CYS G 1 108 ? 5.825    13.768  9.643   1.00 90.20  ? 315 CYS G CB  1 
ATOM   9599  S SG  . CYS G 1 108 ? 4.797    12.513  8.837   1.00 94.03  ? 315 CYS G SG  1 
ATOM   9600  N N   . VAL G 1 109 ? 3.860    13.315  12.250  1.00 87.26  ? 316 VAL G N   1 
ATOM   9601  C CA  . VAL G 1 109 ? 2.608    13.783  12.911  1.00 87.66  ? 316 VAL G CA  1 
ATOM   9602  C C   . VAL G 1 109 ? 2.575    13.307  14.364  1.00 79.60  ? 316 VAL G C   1 
ATOM   9603  O O   . VAL G 1 109 ? 1.490    13.095  14.893  1.00 74.75  ? 316 VAL G O   1 
ATOM   9604  C CB  . VAL G 1 109 ? 1.391    13.288  12.110  1.00 79.59  ? 316 VAL G CB  1 
ATOM   9605  C CG1 . VAL G 1 109 ? 1.154    14.165  10.894  1.00 82.38  ? 316 VAL G CG1 1 
ATOM   9606  C CG2 . VAL G 1 109 ? 1.535    11.834  11.689  1.00 75.71  ? 316 VAL G CG2 1 
ATOM   9607  N N   . GLU G 1 110 ? 3.730    13.098  14.977  1.00 72.22  ? 317 GLU G N   1 
ATOM   9608  C CA  . GLU G 1 110 ? 3.777    12.778  16.392  1.00 70.21  ? 317 GLU G CA  1 
ATOM   9609  C C   . GLU G 1 110 ? 3.310    13.960  17.239  1.00 72.48  ? 317 GLU G C   1 
ATOM   9610  O O   . GLU G 1 110 ? 3.628    15.122  16.964  1.00 78.18  ? 317 GLU G O   1 
ATOM   9611  C CB  . GLU G 1 110 ? 5.196    12.373  16.779  1.00 74.78  ? 317 GLU G CB  1 
ATOM   9612  C CG  . GLU G 1 110 ? 5.365    12.135  18.257  1.00 75.28  ? 317 GLU G CG  1 
ATOM   9613  C CD  . GLU G 1 110 ? 6.587    11.315  18.573  1.00 74.94  ? 317 GLU G CD  1 
ATOM   9614  O OE1 . GLU G 1 110 ? 6.884    11.147  19.774  1.00 70.98  ? 317 GLU G OE1 1 
ATOM   9615  O OE2 . GLU G 1 110 ? 7.243    10.838  17.620  1.00 78.33  ? 317 GLU G OE2 1 
ATOM   9616  N N   . GLY G 1 111 ? 2.556    13.656  18.285  1.00 73.44  ? 318 GLY G N   1 
ATOM   9617  C CA  . GLY G 1 111 ? 1.953    14.669  19.113  1.00 69.20  ? 318 GLY G CA  1 
ATOM   9618  C C   . GLY G 1 111 ? 0.638    15.190  18.589  1.00 67.02  ? 318 GLY G C   1 
ATOM   9619  O O   . GLY G 1 111 ? -0.011   15.994  19.272  1.00 62.74  ? 318 GLY G O   1 
ATOM   9620  N N   . THR G 1 112 ? 0.226    14.749  17.403  1.00 65.79  ? 319 THR G N   1 
ATOM   9621  C CA  . THR G 1 112 ? -0.989   15.268  16.796  1.00 67.21  ? 319 THR G CA  1 
ATOM   9622  C C   . THR G 1 112 ? -2.164   15.167  17.755  1.00 68.11  ? 319 THR G C   1 
ATOM   9623  O O   . THR G 1 112 ? -2.770   16.182  18.121  1.00 66.77  ? 319 THR G O   1 
ATOM   9624  C CB  . THR G 1 112 ? -1.275   14.517  15.499  1.00 72.15  ? 319 THR G CB  1 
ATOM   9625  O OG1 . THR G 1 112 ? -0.306   14.907  14.518  1.00 73.28  ? 319 THR G OG1 1 
ATOM   9626  C CG2 . THR G 1 112 ? -2.669   14.841  14.992  1.00 70.94  ? 319 THR G CG2 1 
ATOM   9627  N N   . ILE G 1 113 ? -2.463   13.948  18.205  1.00 67.04  ? 320 ILE G N   1 
ATOM   9628  C CA  . ILE G 1 113 ? -3.654   13.635  19.000  1.00 64.78  ? 320 ILE G CA  1 
ATOM   9629  C C   . ILE G 1 113 ? -3.577   14.255  20.395  1.00 65.93  ? 320 ILE G C   1 
ATOM   9630  O O   . ILE G 1 113 ? -4.608   14.742  20.899  1.00 62.03  ? 320 ILE G O   1 
ATOM   9631  C CB  . ILE G 1 113 ? -3.882   12.114  19.063  1.00 66.84  ? 320 ILE G CB  1 
ATOM   9632  C CG1 . ILE G 1 113 ? -4.709   11.662  17.856  1.00 62.93  ? 320 ILE G CG1 1 
ATOM   9633  C CG2 . ILE G 1 113 ? -4.567   11.700  20.373  1.00 64.31  ? 320 ILE G CG2 1 
ATOM   9634  C CD1 . ILE G 1 113 ? -4.423   10.255  17.394  1.00 66.73  ? 320 ILE G CD1 1 
ATOM   9635  N N   . PRO G 1 114 ? -2.408   14.278  21.058  1.00 63.46  ? 321 PRO G N   1 
ATOM   9636  C CA  . PRO G 1 114 ? -2.295   15.136  22.257  1.00 60.39  ? 321 PRO G CA  1 
ATOM   9637  C C   . PRO G 1 114 ? -2.525   16.613  21.966  1.00 63.07  ? 321 PRO G C   1 
ATOM   9638  O O   . PRO G 1 114 ? -3.087   17.314  22.816  1.00 63.74  ? 321 PRO G O   1 
ATOM   9639  C CB  . PRO G 1 114 ? -0.867   14.869  22.751  1.00 60.24  ? 321 PRO G CB  1 
ATOM   9640  C CG  . PRO G 1 114 ? -0.541   13.488  22.232  1.00 60.71  ? 321 PRO G CG  1 
ATOM   9641  C CD  . PRO G 1 114 ? -1.234   13.390  20.905  1.00 64.43  ? 321 PRO G CD  1 
ATOM   9642  N N   . LYS G 1 115 ? -2.104   17.114  20.792  1.00 64.53  ? 322 LYS G N   1 
ATOM   9643  C CA  . LYS G 1 115 ? -2.245   18.543  20.507  1.00 66.54  ? 322 LYS G CA  1 
ATOM   9644  C C   . LYS G 1 115 ? -3.707   18.932  20.360  1.00 69.60  ? 322 LYS G C   1 
ATOM   9645  O O   . LYS G 1 115 ? -4.087   20.079  20.643  1.00 67.63  ? 322 LYS G O   1 
ATOM   9646  C CB  . LYS G 1 115 ? -1.471   18.921  19.240  1.00 57.30  ? 322 LYS G CB  1 
ATOM   9647  N N   . LEU G 1 116 ? -4.538   17.980  19.954  1.00 62.90  ? 323 LEU G N   1 
ATOM   9648  C CA  . LEU G 1 116 ? -5.928   18.216  19.611  1.00 63.67  ? 323 LEU G CA  1 
ATOM   9649  C C   . LEU G 1 116 ? -6.892   17.935  20.751  1.00 67.19  ? 323 LEU G C   1 
ATOM   9650  O O   . LEU G 1 116 ? -7.897   18.647  20.900  1.00 66.45  ? 323 LEU G O   1 
ATOM   9651  C CB  . LEU G 1 116 ? -6.306   17.344  18.416  1.00 67.25  ? 323 LEU G CB  1 
ATOM   9652  C CG  . LEU G 1 116 ? -5.976   17.939  17.062  1.00 65.81  ? 323 LEU G CG  1 
ATOM   9653  C CD1 . LEU G 1 116 ? -5.696   16.826  16.074  1.00 73.47  ? 323 LEU G CD1 1 
ATOM   9654  C CD2 . LEU G 1 116 ? -7.151   18.781  16.620  1.00 71.52  ? 323 LEU G CD2 1 
ATOM   9655  N N   . PHE G 1 117 ? -6.627   16.904  21.557  1.00 67.06  ? 324 PHE G N   1 
ATOM   9656  C CA  . PHE G 1 117 ? -7.630   16.412  22.487  1.00 65.02  ? 324 PHE G CA  1 
ATOM   9657  C C   . PHE G 1 117 ? -7.237   16.510  23.954  1.00 62.01  ? 324 PHE G C   1 
ATOM   9658  O O   . PHE G 1 117 ? -8.101   16.299  24.815  1.00 64.21  ? 324 PHE G O   1 
ATOM   9659  C CB  . PHE G 1 117 ? -7.986   14.949  22.160  1.00 63.99  ? 324 PHE G CB  1 
ATOM   9660  C CG  . PHE G 1 117 ? -8.416   14.720  20.731  1.00 58.86  ? 324 PHE G CG  1 
ATOM   9661  C CD1 . PHE G 1 117 ? -9.741   14.865  20.362  1.00 59.14  ? 324 PHE G CD1 1 
ATOM   9662  C CD2 . PHE G 1 117 ? -7.494   14.345  19.768  1.00 60.25  ? 324 PHE G CD2 1 
ATOM   9663  C CE1 . PHE G 1 117 ? -10.144  14.652  19.056  1.00 57.63  ? 324 PHE G CE1 1 
ATOM   9664  C CE2 . PHE G 1 117 ? -7.888   14.128  18.473  1.00 63.34  ? 324 PHE G CE2 1 
ATOM   9665  C CZ  . PHE G 1 117 ? -9.220   14.284  18.116  1.00 65.42  ? 324 PHE G CZ  1 
ATOM   9666  N N   . ARG G 1 118 ? -5.989   16.836  24.274  1.00 62.82  ? 325 ARG G N   1 
ATOM   9667  C CA  . ARG G 1 118 ? -5.492   16.702  25.640  1.00 63.16  ? 325 ARG G CA  1 
ATOM   9668  C C   . ARG G 1 118 ? -5.385   18.058  26.323  1.00 62.92  ? 325 ARG G C   1 
ATOM   9669  O O   . ARG G 1 118 ? -4.669   18.944  25.844  1.00 63.08  ? 325 ARG G O   1 
ATOM   9670  C CB  . ARG G 1 118 ? -4.141   15.988  25.681  1.00 56.19  ? 325 ARG G CB  1 
ATOM   9671  C CG  . ARG G 1 118 ? -3.639   15.788  27.097  1.00 59.11  ? 325 ARG G CG  1 
ATOM   9672  C CD  . ARG G 1 118 ? -2.249   16.355  27.284  1.00 65.20  ? 325 ARG G CD  1 
ATOM   9673  N NE  . ARG G 1 118 ? -1.234   15.375  26.913  1.00 65.33  ? 325 ARG G NE  1 
ATOM   9674  C CZ  . ARG G 1 118 ? -0.025   15.690  26.466  1.00 69.40  ? 325 ARG G CZ  1 
ATOM   9675  N NH1 . ARG G 1 118 ? 0.321    16.967  26.326  1.00 73.35  ? 325 ARG G NH1 1 
ATOM   9676  N NH2 . ARG G 1 118 ? 0.835    14.727  26.160  1.00 68.14  ? 325 ARG G NH2 1 
ATOM   9677  N N   . GLY G 1 119 ? -6.097   18.202  27.439  1.00 64.68  ? 326 GLY G N   1 
ATOM   9678  C CA  . GLY G 1 119 ? -5.939   19.310  28.348  1.00 61.45  ? 326 GLY G CA  1 
ATOM   9679  C C   . GLY G 1 119 ? -5.169   18.878  29.576  1.00 61.67  ? 326 GLY G C   1 
ATOM   9680  O O   . GLY G 1 119 ? -4.440   17.880  29.555  1.00 62.39  ? 326 GLY G O   1 
ATOM   9681  N N   . LYS G 1 120 ? -5.232   19.712  30.614  1.00 57.94  ? 327 LYS G N   1 
ATOM   9682  C CA  . LYS G 1 120 ? -4.603   19.390  31.915  1.00 57.04  ? 327 LYS G CA  1 
ATOM   9683  C C   . LYS G 1 120 ? -5.501   19.977  32.997  1.00 55.61  ? 327 LYS G C   1 
ATOM   9684  O O   . LYS G 1 120 ? -6.071   21.045  32.770  1.00 59.83  ? 327 LYS G O   1 
ATOM   9685  C CB  . LYS G 1 120 ? -3.197   19.969  32.052  1.00 51.22  ? 327 LYS G CB  1 
ATOM   9686  C CG  . LYS G 1 120 ? -2.420   19.471  33.261  1.00 59.10  ? 327 LYS G CG  1 
ATOM   9687  C CD  . LYS G 1 120 ? -0.990   19.936  33.300  1.00 65.51  ? 327 LYS G CD  1 
ATOM   9688  C CE  . LYS G 1 120 ? -0.015   18.887  32.813  1.00 58.06  ? 327 LYS G CE  1 
ATOM   9689  N NZ  . LYS G 1 120 ? -0.229   17.583  33.481  1.00 65.54  ? 327 LYS G NZ  1 
ATOM   9690  N N   . MET G 1 121 ? -5.633   19.278  34.118  1.00 51.45  ? 328 MET G N   1 
ATOM   9691  C CA  . MET G 1 121 ? -6.466   19.776  35.234  1.00 49.64  ? 328 MET G CA  1 
ATOM   9692  C C   . MET G 1 121 ? -5.635   19.903  36.508  1.00 52.87  ? 328 MET G C   1 
ATOM   9693  O O   . MET G 1 121 ? -4.519   19.396  36.529  1.00 53.67  ? 328 MET G O   1 
ATOM   9694  C CB  . MET G 1 121 ? -7.655   18.847  35.488  1.00 54.88  ? 328 MET G CB  1 
ATOM   9695  C CG  . MET G 1 121 ? -7.322   17.374  35.491  1.00 62.88  ? 328 MET G CG  1 
ATOM   9696  S SD  . MET G 1 121 ? -8.746   16.371  35.016  1.00 56.05  ? 328 MET G SD  1 
ATOM   9697  C CE  . MET G 1 121 ? -9.299   15.812  36.624  1.00 53.28  ? 328 MET G CE  1 
ATOM   9698  N N   . VAL G 1 122 ? -6.168   20.602  37.507  1.00 52.14  ? 329 VAL G N   1 
ATOM   9699  C CA  . VAL G 1 122 ? -5.487   20.740  38.825  1.00 50.29  ? 329 VAL G CA  1 
ATOM   9700  C C   . VAL G 1 122 ? -6.417   20.207  39.905  1.00 55.48  ? 329 VAL G C   1 
ATOM   9701  O O   . VAL G 1 122 ? -7.569   20.632  39.926  1.00 55.03  ? 329 VAL G O   1 
ATOM   9702  C CB  . VAL G 1 122 ? -5.143   22.196  39.174  1.00 55.53  ? 329 VAL G CB  1 
ATOM   9703  C CG1 . VAL G 1 122 ? -3.676   22.410  39.468  1.00 53.21  ? 329 VAL G CG1 1 
ATOM   9704  C CG2 . VAL G 1 122 ? -5.685   23.214  38.188  1.00 61.51  ? 329 VAL G CG2 1 
ATOM   9705  N N   . SER G 1 123 ? -5.927   19.318  40.762  1.00 53.68  ? 330 SER G N   1 
ATOM   9706  C CA  . SER G 1 123 ? -6.731   18.869  41.922  1.00 48.43  ? 330 SER G CA  1 
ATOM   9707  C C   . SER G 1 123 ? -6.140   19.521  43.163  1.00 49.08  ? 330 SER G C   1 
ATOM   9708  O O   . SER G 1 123 ? -4.955   19.321  43.423  1.00 57.11  ? 330 SER G O   1 
ATOM   9709  C CB  . SER G 1 123 ? -6.781   17.382  42.048  1.00 46.23  ? 330 SER G CB  1 
ATOM   9710  O OG  . SER G 1 123 ? -7.975   16.870  41.485  1.00 56.90  ? 330 SER G OG  1 
ATOM   9711  N N   . TYR G 1 124 ? -6.946   20.297  43.869  1.00 47.47  ? 331 TYR G N   1 
ATOM   9712  C CA  . TYR G 1 124 ? -6.492   20.983  45.097  1.00 50.46  ? 331 TYR G CA  1 
ATOM   9713  C C   . TYR G 1 124 ? -7.083   20.283  46.312  1.00 55.57  ? 331 TYR G C   1 
ATOM   9714  O O   . TYR G 1 124 ? -8.271   20.029  46.299  1.00 58.17  ? 331 TYR G O   1 
ATOM   9715  C CB  . TYR G 1 124 ? -6.918   22.449  45.076  1.00 45.64  ? 331 TYR G CB  1 
ATOM   9716  C CG  . TYR G 1 124 ? -6.295   23.286  43.991  1.00 53.13  ? 331 TYR G CG  1 
ATOM   9717  C CD1 . TYR G 1 124 ? -5.017   23.792  44.134  1.00 55.00  ? 331 TYR G CD1 1 
ATOM   9718  C CD2 . TYR G 1 124 ? -6.984   23.586  42.830  1.00 58.00  ? 331 TYR G CD2 1 
ATOM   9719  C CE1 . TYR G 1 124 ? -4.428   24.564  43.149  1.00 52.98  ? 331 TYR G CE1 1 
ATOM   9720  C CE2 . TYR G 1 124 ? -6.413   24.361  41.836  1.00 60.56  ? 331 TYR G CE2 1 
ATOM   9721  C CZ  . TYR G 1 124 ? -5.130   24.851  41.996  1.00 62.17  ? 331 TYR G CZ  1 
ATOM   9722  O OH  . TYR G 1 124 ? -4.551   25.617  41.027  1.00 65.58  ? 331 TYR G OH  1 
ATOM   9723  N N   . ILE G 1 125 ? -6.264   19.973  47.309  1.00 56.53  ? 332 ILE G N   1 
ATOM   9724  C CA  . ILE G 1 125 ? -6.708   19.325  48.575  1.00 51.82  ? 332 ILE G CA  1 
ATOM   9725  C C   . ILE G 1 125 ? -6.226   20.184  49.750  1.00 53.46  ? 332 ILE G C   1 
ATOM   9726  O O   . ILE G 1 125 ? -5.033   20.481  49.787  1.00 56.26  ? 332 ILE G O   1 
ATOM   9727  C CB  . ILE G 1 125 ? -6.185   17.879  48.681  1.00 57.54  ? 332 ILE G CB  1 
ATOM   9728  C CG1 . ILE G 1 125 ? -6.324   17.094  47.375  1.00 57.53  ? 332 ILE G CG1 1 
ATOM   9729  C CG2 . ILE G 1 125 ? -6.867   17.158  49.829  1.00 63.47  ? 332 ILE G CG2 1 
ATOM   9730  C CD1 . ILE G 1 125 ? -5.004   16.701  46.755  1.00 59.81  ? 332 ILE G CD1 1 
ATOM   9731  N N   . GLN G 1 126 ? -7.125   20.595  50.649  1.00 60.57  ? 333 GLN G N   1 
ATOM   9732  C CA  . GLN G 1 126 ? -6.756   21.448  51.813  1.00 61.17  ? 333 GLN G CA  1 
ATOM   9733  C C   . GLN G 1 126 ? -7.349   20.900  53.107  1.00 61.17  ? 333 GLN G C   1 
ATOM   9734  O O   . GLN G 1 126 ? -8.573   20.865  53.217  1.00 59.01  ? 333 GLN G O   1 
ATOM   9735  C CB  . GLN G 1 126 ? -7.206   22.896  51.630  1.00 62.23  ? 333 GLN G CB  1 
ATOM   9736  C CG  . GLN G 1 126 ? -6.142   23.909  52.027  1.00 64.93  ? 333 GLN G CG  1 
ATOM   9737  C CD  . GLN G 1 126 ? -6.092   24.132  53.517  1.00 69.59  ? 333 GLN G CD  1 
ATOM   9738  O OE1 . GLN G 1 126 ? -7.057   24.582  54.127  1.00 79.98  ? 333 GLN G OE1 1 
ATOM   9739  N NE2 . GLN G 1 126 ? -4.959   23.813  54.119  1.00 59.59  ? 333 GLN G NE2 1 
ATOM   9740  N N   . CYS G 1 127 ? -6.498   20.594  54.080  1.00 61.23  ? 334 CYS G N   1 
ATOM   9741  C CA  . CYS G 1 127 ? -6.920   20.026  55.352  1.00 59.92  ? 334 CYS G CA  1 
ATOM   9742  C C   . CYS G 1 127 ? -7.713   21.036  56.174  1.00 64.26  ? 334 CYS G C   1 
ATOM   9743  O O   . CYS G 1 127 ? -7.402   22.223  56.195  1.00 66.06  ? 334 CYS G O   1 
ATOM   9744  C CB  . CYS G 1 127 ? -5.700   19.554  56.141  1.00 60.83  ? 334 CYS G CB  1 
ATOM   9745  S SG  . CYS G 1 127 ? -4.981   18.002  55.539  1.00 69.71  ? 334 CYS G SG  1 
ATOM   9746  N N   . LYS G 1 128 ? -8.730   20.549  56.878  1.00 67.39  ? 335 LYS G N   1 
ATOM   9747  C CA  . LYS G 1 128 ? -9.626   21.432  57.611  1.00 69.56  ? 335 LYS G CA  1 
ATOM   9748  C C   . LYS G 1 128 ? -9.100   21.749  59.017  1.00 74.12  ? 335 LYS G C   1 
ATOM   9749  O O   . LYS G 1 128 ? -9.165   22.902  59.454  1.00 79.54  ? 335 LYS G O   1 
ATOM   9750  C CB  . LYS G 1 128 ? -11.027  20.804  57.671  1.00 69.10  ? 335 LYS G CB  1 
ATOM   9751  N N   . GLU G 1 129 ? -8.573   20.758  59.744  1.00 75.35  ? 336 GLU G N   1 
ATOM   9752  C CA  . GLU G 1 129 ? -8.218   20.948  61.149  1.00 73.13  ? 336 GLU G CA  1 
ATOM   9753  C C   . GLU G 1 129 ? -6.715   20.883  61.434  1.00 74.87  ? 336 GLU G C   1 
ATOM   9754  O O   . GLU G 1 129 ? -6.325   20.874  62.605  1.00 79.83  ? 336 GLU G O   1 
ATOM   9755  C CB  . GLU G 1 129 ? -8.953   19.925  62.017  1.00 72.03  ? 336 GLU G CB  1 
ATOM   9756  N N   . VAL G 1 130 ? -5.861   20.811  60.412  1.00 70.58  ? 337 VAL G N   1 
ATOM   9757  C CA  . VAL G 1 130 ? -4.429   21.060  60.549  1.00 67.62  ? 337 VAL G CA  1 
ATOM   9758  C C   . VAL G 1 130 ? -3.982   21.865  59.335  1.00 74.28  ? 337 VAL G C   1 
ATOM   9759  O O   . VAL G 1 130 ? -4.770   22.152  58.431  1.00 74.86  ? 337 VAL G O   1 
ATOM   9760  C CB  . VAL G 1 130 ? -3.583   19.769  60.682  1.00 69.95  ? 337 VAL G CB  1 
ATOM   9761  C CG1 . VAL G 1 130 ? -4.127   18.834  61.747  1.00 66.06  ? 337 VAL G CG1 1 
ATOM   9762  C CG2 . VAL G 1 130 ? -3.436   19.060  59.340  1.00 72.99  ? 337 VAL G CG2 1 
ATOM   9763  N N   . ASP G 1 131 ? -2.700   22.220  59.306  1.00 71.15  ? 338 ASP G N   1 
ATOM   9764  C CA  . ASP G 1 131 ? -2.166   23.084  58.258  1.00 73.61  ? 338 ASP G CA  1 
ATOM   9765  C C   . ASP G 1 131 ? -1.371   22.244  57.256  1.00 76.66  ? 338 ASP G C   1 
ATOM   9766  O O   . ASP G 1 131 ? -0.156   22.079  57.373  1.00 76.86  ? 338 ASP G O   1 
ATOM   9767  C CB  . ASP G 1 131 ? -1.324   24.189  58.878  1.00 81.62  ? 338 ASP G CB  1 
ATOM   9768  C CG  . ASP G 1 131 ? -1.042   25.302  57.914  1.00 84.18  ? 338 ASP G CG  1 
ATOM   9769  O OD1 . ASP G 1 131 ? -1.553   25.239  56.773  1.00 86.50  ? 338 ASP G OD1 1 
ATOM   9770  O OD2 . ASP G 1 131 ? -0.312   26.236  58.298  1.00 89.19  ? 338 ASP G OD2 1 
ATOM   9771  N N   . TYR G 1 132 ? -2.070   21.731  56.242  1.00 72.23  ? 339 TYR G N   1 
ATOM   9772  C CA  . TYR G 1 132 ? -1.472   20.891  55.213  1.00 56.77  ? 339 TYR G CA  1 
ATOM   9773  C C   . TYR G 1 132 ? -2.276   21.094  53.942  1.00 57.11  ? 339 TYR G C   1 
ATOM   9774  O O   . TYR G 1 132 ? -3.495   21.253  54.003  1.00 63.94  ? 339 TYR G O   1 
ATOM   9775  C CB  . TYR G 1 132 ? -1.478   19.430  55.650  1.00 63.56  ? 339 TYR G CB  1 
ATOM   9776  C CG  . TYR G 1 132 ? -0.675   18.438  54.826  1.00 67.31  ? 339 TYR G CG  1 
ATOM   9777  C CD1 . TYR G 1 132 ? -1.235   17.798  53.716  1.00 56.88  ? 339 TYR G CD1 1 
ATOM   9778  C CD2 . TYR G 1 132 ? 0.623    18.086  55.201  1.00 65.89  ? 339 TYR G CD2 1 
ATOM   9779  C CE1 . TYR G 1 132 ? -0.521   16.866  52.995  1.00 49.32  ? 339 TYR G CE1 1 
ATOM   9780  C CE2 . TYR G 1 132 ? 1.350    17.161  54.472  1.00 61.61  ? 339 TYR G CE2 1 
ATOM   9781  C CZ  . TYR G 1 132 ? 0.768    16.552  53.380  1.00 59.34  ? 339 TYR G CZ  1 
ATOM   9782  O OH  . TYR G 1 132 ? 1.493    15.633  52.670  1.00 70.58  ? 339 TYR G OH  1 
ATOM   9783  N N   . ARG G 1 133 ? -1.591   21.122  52.802  1.00 61.61  ? 340 ARG G N   1 
ATOM   9784  C CA  . ARG G 1 133 ? -2.212   21.384  51.506  1.00 56.10  ? 340 ARG G CA  1 
ATOM   9785  C C   . ARG G 1 133 ? -1.431   20.630  50.439  1.00 57.04  ? 340 ARG G C   1 
ATOM   9786  O O   . ARG G 1 133 ? -0.205   20.511  50.539  1.00 60.99  ? 340 ARG G O   1 
ATOM   9787  C CB  . ARG G 1 133 ? -2.238   22.891  51.188  1.00 53.67  ? 340 ARG G CB  1 
ATOM   9788  N N   . SER G 1 134 ? -2.126   20.107  49.430  1.00 54.25  ? 341 SER G N   1 
ATOM   9789  C CA  . SER G 1 134 ? -1.429   19.394  48.367  1.00 52.77  ? 341 SER G CA  1 
ATOM   9790  C C   . SER G 1 134 ? -2.037   19.731  47.008  1.00 50.31  ? 341 SER G C   1 
ATOM   9791  O O   . SER G 1 134 ? -3.133   20.279  46.915  1.00 53.73  ? 341 SER G O   1 
ATOM   9792  C CB  . SER G 1 134 ? -1.425   17.873  48.620  1.00 56.29  ? 341 SER G CB  1 
ATOM   9793  O OG  . SER G 1 134 ? -0.791   17.157  47.559  1.00 55.85  ? 341 SER G OG  1 
ATOM   9794  N N   . ASP G 1 135 ? -1.280   19.446  45.951  1.00 49.14  ? 342 ASP G N   1 
ATOM   9795  C CA  . ASP G 1 135 ? -1.709   19.779  44.575  1.00 50.65  ? 342 ASP G CA  1 
ATOM   9796  C C   . ASP G 1 135 ? -1.367   18.627  43.636  1.00 54.30  ? 342 ASP G C   1 
ATOM   9797  O O   . ASP G 1 135 ? -0.377   17.937  43.901  1.00 59.08  ? 342 ASP G O   1 
ATOM   9798  C CB  . ASP G 1 135 ? -0.938   20.983  44.038  1.00 48.94  ? 342 ASP G CB  1 
ATOM   9799  C CG  . ASP G 1 135 ? -1.455   22.354  44.425  1.00 65.60  ? 342 ASP G CG  1 
ATOM   9800  O OD1 . ASP G 1 135 ? -2.394   22.431  45.226  1.00 74.80  ? 342 ASP G OD1 1 
ATOM   9801  O OD2 . ASP G 1 135 ? -0.895   23.340  43.921  1.00 66.52  ? 342 ASP G OD2 1 
ATOM   9802  N N   . ARG G 1 136 ? -2.149   18.435  42.577  1.00 49.07  ? 343 ARG G N   1 
ATOM   9803  C CA  . ARG G 1 136 ? -1.801   17.429  41.542  1.00 54.65  ? 343 ARG G CA  1 
ATOM   9804  C C   . ARG G 1 136 ? -2.290   17.924  40.187  1.00 53.32  ? 343 ARG G C   1 
ATOM   9805  O O   . ARG G 1 136 ? -3.399   18.432  40.114  1.00 58.87  ? 343 ARG G O   1 
ATOM   9806  C CB  . ARG G 1 136 ? -2.395   16.047  41.812  1.00 52.00  ? 343 ARG G CB  1 
ATOM   9807  C CG  . ARG G 1 136 ? -1.805   14.952  40.936  1.00 48.06  ? 343 ARG G CG  1 
ATOM   9808  C CD  . ARG G 1 136 ? -1.560   13.663  41.687  1.00 55.17  ? 343 ARG G CD  1 
ATOM   9809  N NE  . ARG G 1 136 ? -0.156   13.358  41.906  1.00 57.26  ? 343 ARG G NE  1 
ATOM   9810  C CZ  . ARG G 1 136 ? 0.520    13.649  43.011  1.00 61.67  ? 343 ARG G CZ  1 
ATOM   9811  N NH1 . ARG G 1 136 ? -0.076   14.262  44.019  1.00 64.47  ? 343 ARG G NH1 1 
ATOM   9812  N NH2 . ARG G 1 136 ? 1.794    13.320  43.107  1.00 73.42  ? 343 ARG G NH2 1 
ATOM   9813  N N   . ARG G 1 137 ? -1.469   17.756  39.159  1.00 50.91  ? 344 ARG G N   1 
ATOM   9814  C CA  . ARG G 1 137 ? -1.845   18.161  37.788  1.00 52.11  ? 344 ARG G CA  1 
ATOM   9815  C C   . ARG G 1 137 ? -1.871   16.913  36.909  1.00 59.92  ? 344 ARG G C   1 
ATOM   9816  O O   . ARG G 1 137 ? -0.874   16.179  36.911  1.00 62.03  ? 344 ARG G O   1 
ATOM   9817  C CB  . ARG G 1 137 ? -0.845   19.185  37.261  1.00 53.15  ? 344 ARG G CB  1 
ATOM   9818  C CG  . ARG G 1 137 ? -1.169   20.621  37.631  1.00 56.11  ? 344 ARG G CG  1 
ATOM   9819  C CD  . ARG G 1 137 ? 0.074    21.399  38.003  1.00 48.91  ? 344 ARG G CD  1 
ATOM   9820  N NE  . ARG G 1 137 ? -0.226   22.412  39.000  1.00 49.82  ? 344 ARG G NE  1 
ATOM   9821  C CZ  . ARG G 1 137 ? -0.077   22.256  40.308  1.00 51.85  ? 344 ARG G CZ  1 
ATOM   9822  N NH1 . ARG G 1 137 ? -0.388   23.245  41.126  1.00 49.83  ? 344 ARG G NH1 1 
ATOM   9823  N NH2 . ARG G 1 137 ? 0.388    21.121  40.795  1.00 54.54  ? 344 ARG G NH2 1 
ATOM   9824  N N   . GLU G 1 138 ? -2.963   16.694  36.177  1.00 54.72  ? 345 GLU G N   1 
ATOM   9825  C CA  . GLU G 1 138 ? -3.083   15.484  35.382  1.00 52.10  ? 345 GLU G CA  1 
ATOM   9826  C C   . GLU G 1 138 ? -3.641   15.793  33.995  1.00 58.45  ? 345 GLU G C   1 
ATOM   9827  O O   . GLU G 1 138 ? -4.536   16.631  33.848  1.00 56.16  ? 345 GLU G O   1 
ATOM   9828  C CB  . GLU G 1 138 ? -3.968   14.456  36.112  1.00 51.17  ? 345 GLU G CB  1 
ATOM   9829  N N   . ASP G 1 139 ? -3.158   15.023  33.035  1.00 60.13  ? 346 ASP G N   1 
ATOM   9830  C CA  . ASP G 1 139 ? -3.668   15.156  31.661  1.00 54.62  ? 346 ASP G CA  1 
ATOM   9831  C C   . ASP G 1 139 ? -4.995   14.424  31.535  1.00 56.37  ? 346 ASP G C   1 
ATOM   9832  O O   . ASP G 1 139 ? -5.243   13.518  32.325  1.00 54.79  ? 346 ASP G O   1 
ATOM   9833  C CB  . ASP G 1 139 ? -2.654   14.585  30.672  1.00 53.82  ? 346 ASP G CB  1 
ATOM   9834  C CG  . ASP G 1 139 ? -1.320   15.302  30.674  1.00 62.14  ? 346 ASP G CG  1 
ATOM   9835  O OD1 . ASP G 1 139 ? -1.325   16.535  30.792  1.00 61.77  ? 346 ASP G OD1 1 
ATOM   9836  O OD2 . ASP G 1 139 ? -0.293   14.619  30.538  1.00 67.24  ? 346 ASP G OD2 1 
ATOM   9837  N N   . TYR G 1 140 ? -5.865   14.896  30.662  1.00 59.89  ? 347 TYR G N   1 
ATOM   9838  C CA  . TYR G 1 140 ? -7.111   14.230  30.308  1.00 51.79  ? 347 TYR G CA  1 
ATOM   9839  C C   . TYR G 1 140 ? -7.265   14.310  28.803  1.00 52.16  ? 347 TYR G C   1 
ATOM   9840  O O   . TYR G 1 140 ? -6.637   15.142  28.158  1.00 59.26  ? 347 TYR G O   1 
ATOM   9841  C CB  . TYR G 1 140 ? -8.329   14.857  31.004  1.00 47.74  ? 347 TYR G CB  1 
ATOM   9842  C CG  . TYR G 1 140 ? -8.588   16.296  30.660  1.00 57.23  ? 347 TYR G CG  1 
ATOM   9843  C CD1 . TYR G 1 140 ? -8.003   17.316  31.394  1.00 60.05  ? 347 TYR G CD1 1 
ATOM   9844  C CD2 . TYR G 1 140 ? -9.421   16.639  29.602  1.00 58.00  ? 347 TYR G CD2 1 
ATOM   9845  C CE1 . TYR G 1 140 ? -8.244   18.645  31.102  1.00 63.58  ? 347 TYR G CE1 1 
ATOM   9846  C CE2 . TYR G 1 140 ? -9.668   17.966  29.286  1.00 60.89  ? 347 TYR G CE2 1 
ATOM   9847  C CZ  . TYR G 1 140 ? -9.072   18.974  30.039  1.00 66.27  ? 347 TYR G CZ  1 
ATOM   9848  O OH  . TYR G 1 140 ? -9.306   20.308  29.738  1.00 60.17  ? 347 TYR G OH  1 
ATOM   9849  N N   . TYR G 1 141 ? -8.086   13.431  28.235  1.00 49.10  ? 348 TYR G N   1 
ATOM   9850  C CA  . TYR G 1 141 ? -8.410   13.512  26.820  1.00 48.45  ? 348 TYR G CA  1 
ATOM   9851  C C   . TYR G 1 141 ? -9.903   13.587  26.579  1.00 48.84  ? 348 TYR G C   1 
ATOM   9852  O O   . TYR G 1 141 ? -10.325  13.506  25.423  1.00 55.74  ? 348 TYR G O   1 
ATOM   9853  C CB  . TYR G 1 141 ? -7.857   12.317  26.047  1.00 52.29  ? 348 TYR G CB  1 
ATOM   9854  C CG  . TYR G 1 141 ? -6.374   12.270  25.744  1.00 49.81  ? 348 TYR G CG  1 
ATOM   9855  C CD1 . TYR G 1 141 ? -5.421   12.454  26.724  1.00 47.50  ? 348 TYR G CD1 1 
ATOM   9856  C CD2 . TYR G 1 141 ? -5.938   11.959  24.473  1.00 49.13  ? 348 TYR G CD2 1 
ATOM   9857  C CE1 . TYR G 1 141 ? -4.072   12.369  26.431  1.00 49.34  ? 348 TYR G CE1 1 
ATOM   9858  C CE2 . TYR G 1 141 ? -4.602   11.864  24.172  1.00 50.40  ? 348 TYR G CE2 1 
ATOM   9859  C CZ  . TYR G 1 141 ? -3.671   12.069  25.144  1.00 53.51  ? 348 TYR G CZ  1 
ATOM   9860  O OH  . TYR G 1 141 ? -2.338   11.968  24.806  1.00 54.05  ? 348 TYR G OH  1 
ATOM   9861  N N   . ASP G 1 142 ? -10.666  13.667  27.665  1.00 46.02  ? 349 ASP G N   1 
ATOM   9862  C CA  . ASP G 1 142 ? -12.142  13.805  27.617  1.00 46.59  ? 349 ASP G CA  1 
ATOM   9863  C C   . ASP G 1 142 ? -12.604  14.276  28.996  1.00 50.40  ? 349 ASP G C   1 
ATOM   9864  O O   . ASP G 1 142 ? -11.807  14.233  29.940  1.00 59.29  ? 349 ASP G O   1 
ATOM   9865  C CB  . ASP G 1 142 ? -12.871  12.523  27.206  1.00 56.29  ? 349 ASP G CB  1 
ATOM   9866  C CG  . ASP G 1 142 ? -12.499  11.249  27.935  1.00 61.57  ? 349 ASP G CG  1 
ATOM   9867  O OD1 . ASP G 1 142 ? -11.849  11.313  28.992  1.00 59.45  ? 349 ASP G OD1 1 
ATOM   9868  O OD2 . ASP G 1 142 ? -12.887  10.198  27.433  1.00 63.94  ? 349 ASP G OD2 1 
ATOM   9869  N N   . ILE G 1 143 ? -13.854  14.700  29.106  1.00 45.55  ? 350 ILE G N   1 
ATOM   9870  C CA  . ILE G 1 143 ? -14.404  15.149  30.420  1.00 50.31  ? 350 ILE G CA  1 
ATOM   9871  C C   . ILE G 1 143 ? -15.650  14.332  30.758  1.00 55.19  ? 350 ILE G C   1 
ATOM   9872  O O   . ILE G 1 143 ? -16.463  14.117  29.863  1.00 55.63  ? 350 ILE G O   1 
ATOM   9873  C CB  . ILE G 1 143 ? -14.668  16.668  30.445  1.00 46.66  ? 350 ILE G CB  1 
ATOM   9874  C CG1 . ILE G 1 143 ? -13.439  17.475  30.031  1.00 50.63  ? 350 ILE G CG1 1 
ATOM   9875  C CG2 . ILE G 1 143 ? -15.187  17.126  31.798  1.00 46.14  ? 350 ILE G CG2 1 
ATOM   9876  C CD1 . ILE G 1 143 ? -13.707  18.947  29.924  1.00 52.29  ? 350 ILE G CD1 1 
ATOM   9877  N N   . GLN G 1 144 ? -15.777  13.895  32.008  1.00 51.77  ? 351 GLN G N   1 
ATOM   9878  C CA  . GLN G 1 144 ? -16.883  13.088  32.498  1.00 47.95  ? 351 GLN G CA  1 
ATOM   9879  C C   . GLN G 1 144 ? -17.791  13.988  33.310  1.00 53.27  ? 351 GLN G C   1 
ATOM   9880  O O   . GLN G 1 144 ? -17.426  14.396  34.417  1.00 53.74  ? 351 GLN G O   1 
ATOM   9881  C CB  . GLN G 1 144 ? -16.370  11.935  33.350  1.00 53.39  ? 351 GLN G CB  1 
ATOM   9882  C CG  . GLN G 1 144 ? -15.934  10.728  32.553  1.00 51.43  ? 351 GLN G CG  1 
ATOM   9883  C CD  . GLN G 1 144 ? -14.587  10.911  31.899  1.00 56.90  ? 351 GLN G CD  1 
ATOM   9884  O OE1 . GLN G 1 144 ? -13.607  11.307  32.545  1.00 54.37  ? 351 GLN G OE1 1 
ATOM   9885  N NE2 . GLN G 1 144 ? -14.523  10.623  30.603  1.00 61.78  ? 351 GLN G NE2 1 
ATOM   9886  N N   . LEU G 1 145 ? -18.955  14.293  32.744  1.00 60.18  ? 352 LEU G N   1 
ATOM   9887  C CA  . LEU G 1 145 ? -19.833  15.298  33.384  1.00 59.48  ? 352 LEU G CA  1 
ATOM   9888  C C   . LEU G 1 145 ? -21.046  14.686  34.068  1.00 52.97  ? 352 LEU G C   1 
ATOM   9889  O O   . LEU G 1 145 ? -21.883  14.142  33.364  1.00 55.86  ? 352 LEU G O   1 
ATOM   9890  C CB  . LEU G 1 145 ? -20.270  16.276  32.292  1.00 58.77  ? 352 LEU G CB  1 
ATOM   9891  C CG  . LEU G 1 145 ? -19.242  17.324  31.878  1.00 57.55  ? 352 LEU G CG  1 
ATOM   9892  C CD1 . LEU G 1 145 ? -19.734  18.084  30.662  1.00 58.01  ? 352 LEU G CD1 1 
ATOM   9893  C CD2 . LEU G 1 145 ? -18.962  18.283  33.020  1.00 62.78  ? 352 LEU G CD2 1 
ATOM   9894  N N   . SER G 1 146 ? -21.132  14.816  35.386  1.00 55.30  ? 353 SER G N   1 
ATOM   9895  C CA  . SER G 1 146 ? -22.297  14.413  36.161  1.00 55.91  ? 353 SER G CA  1 
ATOM   9896  C C   . SER G 1 146 ? -23.582  14.974  35.554  1.00 63.41  ? 353 SER G C   1 
ATOM   9897  O O   . SER G 1 146 ? -23.602  16.108  35.065  1.00 69.80  ? 353 SER G O   1 
ATOM   9898  C CB  . SER G 1 146 ? -22.121  14.895  37.603  1.00 55.17  ? 353 SER G CB  1 
ATOM   9899  O OG  . SER G 1 146 ? -23.359  15.048  38.262  1.00 67.53  ? 353 SER G OG  1 
ATOM   9900  N N   . ILE G 1 147 ? -24.663  14.172  35.582  1.00 65.07  ? 354 ILE G N   1 
ATOM   9901  C CA  . ILE G 1 147 ? -25.899  14.497  34.876  1.00 66.00  ? 354 ILE G CA  1 
ATOM   9902  C C   . ILE G 1 147 ? -27.110  14.538  35.803  1.00 64.30  ? 354 ILE G C   1 
ATOM   9903  O O   . ILE G 1 147 ? -27.958  15.428  35.673  1.00 62.86  ? 354 ILE G O   1 
ATOM   9904  C CB  . ILE G 1 147 ? -26.153  13.515  33.709  1.00 60.40  ? 354 ILE G CB  1 
ATOM   9905  C CG1 . ILE G 1 147 ? -25.029  13.591  32.677  1.00 62.81  ? 354 ILE G CG1 1 
ATOM   9906  C CG2 . ILE G 1 147 ? -27.450  13.813  33.050  1.00 55.39  ? 354 ILE G CG2 1 
ATOM   9907  C CD1 . ILE G 1 147 ? -25.268  14.553  31.563  1.00 61.40  ? 354 ILE G CD1 1 
ATOM   9908  N N   . LYS G 1 148 ? -27.229  13.586  36.730  1.00 65.95  ? 355 LYS G N   1 
ATOM   9909  C CA  . LYS G 1 148 ? -28.430  13.515  37.558  1.00 66.93  ? 355 LYS G CA  1 
ATOM   9910  C C   . LYS G 1 148 ? -28.531  14.757  38.427  1.00 62.73  ? 355 LYS G C   1 
ATOM   9911  O O   . LYS G 1 148 ? -27.535  15.215  38.992  1.00 67.34  ? 355 LYS G O   1 
ATOM   9912  C CB  . LYS G 1 148 ? -28.439  12.257  38.435  1.00 61.32  ? 355 LYS G CB  1 
ATOM   9913  N N   . GLY G 1 149 ? -29.720  15.343  38.497  1.00 63.10  ? 356 GLY G N   1 
ATOM   9914  C CA  . GLY G 1 149 ? -29.926  16.532  39.344  1.00 73.57  ? 356 GLY G CA  1 
ATOM   9915  C C   . GLY G 1 149 ? -29.427  17.815  38.706  1.00 73.37  ? 356 GLY G C   1 
ATOM   9916  O O   . GLY G 1 149 ? -29.596  18.873  39.329  1.00 75.20  ? 356 GLY G O   1 
ATOM   9917  N N   . LYS G 1 150 ? -28.829  17.731  37.518  1.00 66.94  ? 357 LYS G N   1 
ATOM   9918  C CA  . LYS G 1 150 ? -28.298  18.906  36.849  1.00 66.05  ? 357 LYS G CA  1 
ATOM   9919  C C   . LYS G 1 150 ? -29.174  19.173  35.643  1.00 72.52  ? 357 LYS G C   1 
ATOM   9920  O O   . LYS G 1 150 ? -29.619  18.231  34.985  1.00 75.16  ? 357 LYS G O   1 
ATOM   9921  C CB  . LYS G 1 150 ? -26.840  18.711  36.407  1.00 72.70  ? 357 LYS G CB  1 
ATOM   9922  C CG  . LYS G 1 150 ? -25.958  17.857  37.342  1.00 67.31  ? 357 LYS G CG  1 
ATOM   9923  C CD  . LYS G 1 150 ? -25.445  18.648  38.530  1.00 64.06  ? 357 LYS G CD  1 
ATOM   9924  C CE  . LYS G 1 150 ? -24.561  17.783  39.416  1.00 70.51  ? 357 LYS G CE  1 
ATOM   9925  N NZ  . LYS G 1 150 ? -25.278  16.720  40.180  1.00 66.06  ? 357 LYS G NZ  1 
ATOM   9926  N N   . LYS G 1 151 ? -29.423  20.455  35.362  1.00 78.14  ? 358 LYS G N   1 
ATOM   9927  C CA  . LYS G 1 151 ? -30.397  20.840  34.349  1.00 77.10  ? 358 LYS G CA  1 
ATOM   9928  C C   . LYS G 1 151 ? -29.777  21.196  33.005  1.00 76.44  ? 358 LYS G C   1 
ATOM   9929  O O   . LYS G 1 151 ? -30.492  21.203  31.996  1.00 76.74  ? 358 LYS G O   1 
ATOM   9930  C CB  . LYS G 1 151 ? -31.234  22.024  34.851  1.00 81.06  ? 358 LYS G CB  1 
ATOM   9931  N N   . ASN G 1 152 ? -28.473  21.469  32.966  1.00 81.54  ? 359 ASN G N   1 
ATOM   9932  C CA  . ASN G 1 152 ? -27.801  21.912  31.750  1.00 77.42  ? 359 ASN G CA  1 
ATOM   9933  C C   . ASN G 1 152 ? -26.296  21.720  31.903  1.00 77.53  ? 359 ASN G C   1 
ATOM   9934  O O   . ASN G 1 152 ? -25.783  21.553  33.013  1.00 76.24  ? 359 ASN G O   1 
ATOM   9935  C CB  . ASN G 1 152 ? -28.114  23.377  31.449  1.00 75.24  ? 359 ASN G CB  1 
ATOM   9936  C CG  . ASN G 1 152 ? -27.956  24.264  32.665  1.00 74.78  ? 359 ASN G CG  1 
ATOM   9937  O OD1 . ASN G 1 152 ? -27.549  23.810  33.739  1.00 78.30  ? 359 ASN G OD1 1 
ATOM   9938  N ND2 . ASN G 1 152 ? -28.279  25.538  32.504  1.00 76.70  ? 359 ASN G ND2 1 
ATOM   9939  N N   . ILE G 1 153 ? -25.588  21.791  30.767  1.00 77.27  ? 360 ILE G N   1 
ATOM   9940  C CA  . ILE G 1 153 ? -24.131  21.632  30.758  1.00 73.07  ? 360 ILE G CA  1 
ATOM   9941  C C   . ILE G 1 153 ? -23.401  22.691  31.586  1.00 73.73  ? 360 ILE G C   1 
ATOM   9942  O O   . ILE G 1 153 ? -22.274  22.453  32.030  1.00 73.73  ? 360 ILE G O   1 
ATOM   9943  C CB  . ILE G 1 153 ? -23.584  21.634  29.320  1.00 72.24  ? 360 ILE G CB  1 
ATOM   9944  C CG1 . ILE G 1 153 ? -22.417  20.668  29.217  1.00 67.97  ? 360 ILE G CG1 1 
ATOM   9945  C CG2 . ILE G 1 153 ? -23.079  23.022  28.947  1.00 76.48  ? 360 ILE G CG2 1 
ATOM   9946  C CD1 . ILE G 1 153 ? -22.085  20.299  27.825  1.00 71.87  ? 360 ILE G CD1 1 
ATOM   9947  N N   . PHE G 1 154 ? -23.992  23.865  31.791  1.00 70.19  ? 361 PHE G N   1 
ATOM   9948  C CA  . PHE G 1 154 ? -23.387  24.790  32.737  1.00 76.41  ? 361 PHE G CA  1 
ATOM   9949  C C   . PHE G 1 154 ? -23.403  24.195  34.144  1.00 77.05  ? 361 PHE G C   1 
ATOM   9950  O O   . PHE G 1 154 ? -22.349  24.012  34.764  1.00 74.87  ? 361 PHE G O   1 
ATOM   9951  C CB  . PHE G 1 154 ? -24.094  26.152  32.701  1.00 76.07  ? 361 PHE G CB  1 
ATOM   9952  N N   . GLU G 1 155 ? -24.592  23.859  34.661  1.00 78.19  ? 362 GLU G N   1 
ATOM   9953  C CA  . GLU G 1 155 ? -24.682  23.359  36.035  1.00 75.66  ? 362 GLU G CA  1 
ATOM   9954  C C   . GLU G 1 155 ? -23.839  22.102  36.244  1.00 71.76  ? 362 GLU G C   1 
ATOM   9955  O O   . GLU G 1 155 ? -23.471  21.794  37.388  1.00 74.68  ? 362 GLU G O   1 
ATOM   9956  C CB  . GLU G 1 155 ? -26.146  23.092  36.409  1.00 79.05  ? 362 GLU G CB  1 
ATOM   9957  N N   . SER G 1 156 ? -23.514  21.389  35.168  1.00 65.49  ? 363 SER G N   1 
ATOM   9958  C CA  . SER G 1 156 ? -22.652  20.190  35.288  1.00 68.35  ? 363 SER G CA  1 
ATOM   9959  C C   . SER G 1 156 ? -21.237  20.634  35.621  1.00 69.40  ? 363 SER G C   1 
ATOM   9960  O O   . SER G 1 156 ? -20.711  20.200  36.647  1.00 67.01  ? 363 SER G O   1 
ATOM   9961  C CB  . SER G 1 156 ? -22.660  19.413  34.021  1.00 66.09  ? 363 SER G CB  1 
ATOM   9962  O OG  . SER G 1 156 ? -22.149  18.115  34.237  1.00 64.99  ? 363 SER G OG  1 
ATOM   9963  N N   . PHE G 1 157 ? -20.659  21.469  34.765  1.00 68.46  ? 364 PHE G N   1 
ATOM   9964  C CA  . PHE G 1 157 ? -19.289  21.997  34.970  1.00 62.85  ? 364 PHE G CA  1 
ATOM   9965  C C   . PHE G 1 157 ? -19.179  22.744  36.301  1.00 63.81  ? 364 PHE G C   1 
ATOM   9966  O O   . PHE G 1 157 ? -18.061  22.852  36.807  1.00 68.50  ? 364 PHE G O   1 
ATOM   9967  C CB  . PHE G 1 157 ? -18.924  22.910  33.801  1.00 60.18  ? 364 PHE G CB  1 
ATOM   9968  C CG  . PHE G 1 157 ? -18.219  22.260  32.642  1.00 54.14  ? 364 PHE G CG  1 
ATOM   9969  C CD1 . PHE G 1 157 ? -16.902  21.853  32.753  1.00 50.59  ? 364 PHE G CD1 1 
ATOM   9970  C CD2 . PHE G 1 157 ? -18.866  22.087  31.431  1.00 56.16  ? 364 PHE G CD2 1 
ATOM   9971  C CE1 . PHE G 1 157 ? -16.254  21.264  31.681  1.00 58.40  ? 364 PHE G CE1 1 
ATOM   9972  C CE2 . PHE G 1 157 ? -18.217  21.496  30.360  1.00 58.55  ? 364 PHE G CE2 1 
ATOM   9973  C CZ  . PHE G 1 157 ? -16.911  21.088  30.487  1.00 56.72  ? 364 PHE G CZ  1 
ATOM   9974  N N   . VAL G 1 158 ? -20.279  23.252  36.852  1.00 58.75  ? 365 VAL G N   1 
ATOM   9975  C CA  . VAL G 1 158 ? -20.180  23.891  38.154  1.00 61.47  ? 365 VAL G CA  1 
ATOM   9976  C C   . VAL G 1 158 ? -19.986  22.847  39.242  1.00 63.30  ? 365 VAL G C   1 
ATOM   9977  O O   . VAL G 1 158 ? -19.120  22.995  40.110  1.00 63.42  ? 365 VAL G O   1 
ATOM   9978  C CB  . VAL G 1 158 ? -21.402  24.782  38.428  1.00 59.65  ? 365 VAL G CB  1 
ATOM   9979  C CG1 . VAL G 1 158 ? -21.277  25.425  39.800  1.00 60.23  ? 365 VAL G CG1 1 
ATOM   9980  C CG2 . VAL G 1 158 ? -21.501  25.831  37.361  1.00 65.77  ? 365 VAL G CG2 1 
ATOM   9981  N N   . ASP G 1 159 ? -20.785  21.775  39.220  1.00 66.68  ? 366 ASP G N   1 
ATOM   9982  C CA  . ASP G 1 159 ? -20.564  20.703  40.189  1.00 68.52  ? 366 ASP G CA  1 
ATOM   9983  C C   . ASP G 1 159 ? -19.178  20.107  40.012  1.00 64.12  ? 366 ASP G C   1 
ATOM   9984  O O   . ASP G 1 159 ? -18.518  19.749  40.996  1.00 57.73  ? 366 ASP G O   1 
ATOM   9985  C CB  . ASP G 1 159 ? -21.652  19.620  40.061  1.00 74.27  ? 366 ASP G CB  1 
ATOM   9986  C CG  . ASP G 1 159 ? -21.615  18.588  41.211  1.00 77.76  ? 366 ASP G CG  1 
ATOM   9987  O OD1 . ASP G 1 159 ? -21.352  18.989  42.370  1.00 82.50  ? 366 ASP G OD1 1 
ATOM   9988  O OD2 . ASP G 1 159 ? -21.843  17.377  40.963  1.00 72.85  ? 366 ASP G OD2 1 
ATOM   9989  N N   . TYR G 1 160 ? -18.705  20.062  38.767  1.00 59.38  ? 367 TYR G N   1 
ATOM   9990  C CA  . TYR G 1 160 ? -17.373  19.554  38.477  1.00 56.45  ? 367 TYR G CA  1 
ATOM   9991  C C   . TYR G 1 160 ? -16.300  20.268  39.293  1.00 60.01  ? 367 TYR G C   1 
ATOM   9992  O O   . TYR G 1 160 ? -15.445  19.621  39.907  1.00 61.78  ? 367 TYR G O   1 
ATOM   9993  C CB  . TYR G 1 160 ? -17.089  19.684  36.988  1.00 51.63  ? 367 TYR G CB  1 
ATOM   9994  C CG  . TYR G 1 160 ? -16.018  18.731  36.566  1.00 60.24  ? 367 TYR G CG  1 
ATOM   9995  C CD1 . TYR G 1 160 ? -14.708  18.905  36.978  1.00 54.67  ? 367 TYR G CD1 1 
ATOM   9996  C CD2 . TYR G 1 160 ? -16.322  17.617  35.793  1.00 55.91  ? 367 TYR G CD2 1 
ATOM   9997  C CE1 . TYR G 1 160 ? -13.742  18.011  36.615  1.00 62.46  ? 367 TYR G CE1 1 
ATOM   9998  C CE2 . TYR G 1 160 ? -15.352  16.725  35.419  1.00 53.97  ? 367 TYR G CE2 1 
ATOM   9999  C CZ  . TYR G 1 160 ? -14.066  16.918  35.835  1.00 56.69  ? 367 TYR G CZ  1 
ATOM   10000 O OH  . TYR G 1 160 ? -13.094  16.015  35.472  1.00 56.66  ? 367 TYR G OH  1 
ATOM   10001 N N   . VAL G 1 161 ? -16.311  21.601  39.300  1.00 58.77  ? 368 VAL G N   1 
ATOM   10002 C CA  . VAL G 1 161 ? -15.318  22.337  40.074  1.00 56.98  ? 368 VAL G CA  1 
ATOM   10003 C C   . VAL G 1 161 ? -15.882  22.702  41.447  1.00 57.99  ? 368 VAL G C   1 
ATOM   10004 O O   . VAL G 1 161 ? -15.313  23.525  42.176  1.00 66.92  ? 368 VAL G O   1 
ATOM   10005 C CB  . VAL G 1 161 ? -14.820  23.587  39.321  1.00 63.16  ? 368 VAL G CB  1 
ATOM   10006 C CG1 . VAL G 1 161 ? -14.375  23.229  37.900  1.00 56.98  ? 368 VAL G CG1 1 
ATOM   10007 C CG2 . VAL G 1 161 ? -15.865  24.711  39.336  1.00 63.88  ? 368 VAL G CG2 1 
ATOM   10008 N N   . ALA G 1 162 ? -16.984  22.075  41.834  1.00 59.17  ? 369 ALA G N   1 
ATOM   10009 C CA  . ALA G 1 162 ? -17.497  22.303  43.174  1.00 59.05  ? 369 ALA G CA  1 
ATOM   10010 C C   . ALA G 1 162 ? -16.548  21.714  44.198  1.00 55.36  ? 369 ALA G C   1 
ATOM   10011 O O   . ALA G 1 162 ? -15.923  20.677  43.977  1.00 63.15  ? 369 ALA G O   1 
ATOM   10012 C CB  . ALA G 1 162 ? -18.880  21.686  43.349  1.00 60.45  ? 369 ALA G CB  1 
ATOM   10013 N N   . VAL G 1 163 ? -16.443  22.381  45.325  1.00 55.36  ? 370 VAL G N   1 
ATOM   10014 C CA  . VAL G 1 163 ? -15.608  21.883  46.406  1.00 59.95  ? 370 VAL G CA  1 
ATOM   10015 C C   . VAL G 1 163 ? -16.327  20.733  47.094  1.00 62.08  ? 370 VAL G C   1 
ATOM   10016 O O   . VAL G 1 163 ? -17.522  20.818  47.384  1.00 62.99  ? 370 VAL G O   1 
ATOM   10017 C CB  . VAL G 1 163 ? -15.268  23.012  47.388  1.00 55.38  ? 370 VAL G CB  1 
ATOM   10018 C CG1 . VAL G 1 163 ? -14.919  22.450  48.741  1.00 62.58  ? 370 VAL G CG1 1 
ATOM   10019 C CG2 . VAL G 1 163 ? -14.110  23.832  46.829  1.00 45.03  ? 370 VAL G CG2 1 
ATOM   10020 N N   . GLU G 1 164 ? -15.604  19.647  47.336  1.00 60.37  ? 371 GLU G N   1 
ATOM   10021 C CA  . GLU G 1 164 ? -16.114  18.499  48.061  1.00 59.65  ? 371 GLU G CA  1 
ATOM   10022 C C   . GLU G 1 164 ? -15.482  18.448  49.440  1.00 66.50  ? 371 GLU G C   1 
ATOM   10023 O O   . GLU G 1 164 ? -14.460  19.089  49.697  1.00 68.72  ? 371 GLU G O   1 
ATOM   10024 C CB  . GLU G 1 164 ? -15.792  17.195  47.339  1.00 59.17  ? 371 GLU G CB  1 
ATOM   10025 C CG  . GLU G 1 164 ? -15.840  17.264  45.858  1.00 59.90  ? 371 GLU G CG  1 
ATOM   10026 C CD  . GLU G 1 164 ? -15.782  15.890  45.288  1.00 63.33  ? 371 GLU G CD  1 
ATOM   10027 O OE1 . GLU G 1 164 ? -16.055  14.967  46.077  1.00 63.21  ? 371 GLU G OE1 1 
ATOM   10028 O OE2 . GLU G 1 164 ? -15.479  15.723  44.084  1.00 67.44  ? 371 GLU G OE2 1 
ATOM   10029 N N   . GLN G 1 165 ? -16.075  17.642  50.316  1.00 63.28  ? 372 GLN G N   1 
ATOM   10030 C CA  . GLN G 1 165 ? -15.485  17.341  51.611  1.00 62.19  ? 372 GLN G CA  1 
ATOM   10031 C C   . GLN G 1 165 ? -15.010  15.890  51.630  1.00 60.40  ? 372 GLN G C   1 
ATOM   10032 O O   . GLN G 1 165 ? -15.713  14.995  51.154  1.00 62.44  ? 372 GLN G O   1 
ATOM   10033 C CB  . GLN G 1 165 ? -16.484  17.607  52.739  1.00 66.66  ? 372 GLN G CB  1 
ATOM   10034 C CG  . GLN G 1 165 ? -17.113  18.981  52.682  1.00 65.49  ? 372 GLN G CG  1 
ATOM   10035 C CD  . GLN G 1 165 ? -16.102  20.086  52.912  1.00 70.32  ? 372 GLN G CD  1 
ATOM   10036 O OE1 . GLN G 1 165 ? -16.097  21.085  52.197  1.00 73.07  ? 372 GLN G OE1 1 
ATOM   10037 N NE2 . GLN G 1 165 ? -15.246  19.918  53.919  1.00 66.01  ? 372 GLN G NE2 1 
ATOM   10038 N N   . LEU G 1 166 ? -13.798  15.695  52.140  1.00 58.29  ? 373 LEU G N   1 
ATOM   10039 C CA  . LEU G 1 166 ? -13.232  14.336  52.278  1.00 57.22  ? 373 LEU G CA  1 
ATOM   10040 C C   . LEU G 1 166 ? -13.300  14.002  53.763  1.00 58.86  ? 373 LEU G C   1 
ATOM   10041 O O   . LEU G 1 166 ? -12.364  14.352  54.481  1.00 63.52  ? 373 LEU G O   1 
ATOM   10042 C CB  . LEU G 1 166 ? -11.796  14.355  51.747  1.00 49.55  ? 373 LEU G CB  1 
ATOM   10043 C CG  . LEU G 1 166 ? -11.637  14.543  50.241  1.00 53.58  ? 373 LEU G CG  1 
ATOM   10044 C CD1 . LEU G 1 166 ? -10.174  14.735  49.884  1.00 48.13  ? 373 LEU G CD1 1 
ATOM   10045 C CD2 . LEU G 1 166 ? -12.215  13.361  49.482  1.00 54.29  ? 373 LEU G CD2 1 
ATOM   10046 N N   . ASP G 1 167 ? -14.373  13.344  54.194  1.00 58.04  ? 374 ASP G N   1 
ATOM   10047 C CA  . ASP G 1 167 ? -14.589  13.096  55.611  1.00 62.96  ? 374 ASP G CA  1 
ATOM   10048 C C   . ASP G 1 167 ? -15.038  11.652  55.805  1.00 65.51  ? 374 ASP G C   1 
ATOM   10049 O O   . ASP G 1 167 ? -15.338  10.930  54.847  1.00 62.58  ? 374 ASP G O   1 
ATOM   10050 C CB  . ASP G 1 167 ? -15.617  14.076  56.210  1.00 58.87  ? 374 ASP G CB  1 
ATOM   10051 C CG  . ASP G 1 167 ? -16.789  14.341  55.276  1.00 66.94  ? 374 ASP G CG  1 
ATOM   10052 O OD1 . ASP G 1 167 ? -17.174  13.429  54.512  1.00 72.77  ? 374 ASP G OD1 1 
ATOM   10053 O OD2 . ASP G 1 167 ? -17.332  15.461  55.296  1.00 75.66  ? 374 ASP G OD2 1 
ATOM   10054 N N   . GLY G 1 168 ? -15.079  11.245  57.073  1.00 63.31  ? 375 GLY G N   1 
ATOM   10055 C CA  . GLY G 1 168 ? -15.502  9.918   57.481  1.00 60.26  ? 375 GLY G CA  1 
ATOM   10056 C C   . GLY G 1 168 ? -14.723  8.768   56.882  1.00 62.68  ? 375 GLY G C   1 
ATOM   10057 O O   . GLY G 1 168 ? -13.560  8.528   57.232  1.00 65.59  ? 375 GLY G O   1 
ATOM   10058 N N   . ASP G 1 169 ? -15.376  8.038   55.981  1.00 63.12  ? 376 ASP G N   1 
ATOM   10059 C CA  . ASP G 1 169 ? -14.781  6.899   55.301  1.00 55.55  ? 376 ASP G CA  1 
ATOM   10060 C C   . ASP G 1 169 ? -13.891  7.318   54.136  1.00 51.75  ? 376 ASP G C   1 
ATOM   10061 O O   . ASP G 1 169 ? -13.315  6.455   53.473  1.00 45.57  ? 376 ASP G O   1 
ATOM   10062 C CB  . ASP G 1 169 ? -15.903  5.967   54.835  1.00 55.88  ? 376 ASP G CB  1 
ATOM   10063 C CG  . ASP G 1 169 ? -15.423  4.572   54.529  1.00 56.72  ? 376 ASP G CG  1 
ATOM   10064 O OD1 . ASP G 1 169 ? -14.424  4.132   55.133  1.00 58.62  ? 376 ASP G OD1 1 
ATOM   10065 O OD2 . ASP G 1 169 ? -16.048  3.915   53.671  1.00 57.57  ? 376 ASP G OD2 1 
ATOM   10066 N N   . ASN G 1 170 ? -13.780  8.624   53.911  1.00 55.33  ? 377 ASN G N   1 
ATOM   10067 C CA  . ASN G 1 170 ? -12.944  9.147   52.804  1.00 53.70  ? 377 ASN G CA  1 
ATOM   10068 C C   . ASN G 1 170 ? -12.029  10.261  53.325  1.00 57.10  ? 377 ASN G C   1 
ATOM   10069 O O   . ASN G 1 170 ? -11.865  11.237  52.605  1.00 57.79  ? 377 ASN G O   1 
ATOM   10070 C CB  . ASN G 1 170 ? -13.801  9.583   51.614  1.00 48.54  ? 377 ASN G CB  1 
ATOM   10071 C CG  . ASN G 1 170 ? -14.694  8.491   51.074  1.00 53.26  ? 377 ASN G CG  1 
ATOM   10072 O OD1 . ASN G 1 170 ? -14.226  7.591   50.393  1.00 52.84  ? 377 ASN G OD1 1 
ATOM   10073 N ND2 . ASN G 1 170 ? -15.979  8.562   51.373  1.00 44.51  ? 377 ASN G ND2 1 
ATOM   10074 N N   . LYS G 1 171 ? -11.429  10.103  54.510  1.00 58.28  ? 378 LYS G N   1 
ATOM   10075 C CA  . LYS G 1 171 ? -10.477  11.073  55.030  1.00 54.09  ? 378 LYS G CA  1 
ATOM   10076 C C   . LYS G 1 171 ? -9.227   11.125  54.157  1.00 56.06  ? 378 LYS G C   1 
ATOM   10077 O O   . LYS G 1 171 ? -8.732   10.094  53.697  1.00 59.37  ? 378 LYS G O   1 
ATOM   10078 C CB  . LYS G 1 171 ? -10.079  10.697  56.454  1.00 56.40  ? 378 LYS G CB  1 
ATOM   10079 C CG  . LYS G 1 171 ? -11.202  10.757  57.467  1.00 61.91  ? 378 LYS G CG  1 
ATOM   10080 C CD  . LYS G 1 171 ? -10.685  10.339  58.832  1.00 65.10  ? 378 LYS G CD  1 
ATOM   10081 C CE  . LYS G 1 171 ? -11.285  11.167  59.942  1.00 60.78  ? 378 LYS G CE  1 
ATOM   10082 N NZ  . LYS G 1 171 ? -10.337  11.245  61.088  1.00 62.24  ? 378 LYS G NZ  1 
ATOM   10083 N N   . TYR G 1 172 ? -8.692   12.326  53.954  1.00 54.95  ? 379 TYR G N   1 
ATOM   10084 C CA  . TYR G 1 172 ? -7.465   12.479  53.184  1.00 55.78  ? 379 TYR G CA  1 
ATOM   10085 C C   . TYR G 1 172 ? -6.263   12.018  53.997  1.00 54.55  ? 379 TYR G C   1 
ATOM   10086 O O   . TYR G 1 172 ? -6.195   12.212  55.208  1.00 57.80  ? 379 TYR G O   1 
ATOM   10087 C CB  . TYR G 1 172 ? -7.277   13.938  52.759  1.00 58.91  ? 379 TYR G CB  1 
ATOM   10088 C CG  . TYR G 1 172 ? -5.950   14.251  52.097  1.00 55.35  ? 379 TYR G CG  1 
ATOM   10089 C CD1 . TYR G 1 172 ? -5.659   13.777  50.825  1.00 53.66  ? 379 TYR G CD1 1 
ATOM   10090 C CD2 . TYR G 1 172 ? -4.997   15.033  52.739  1.00 54.84  ? 379 TYR G CD2 1 
ATOM   10091 C CE1 . TYR G 1 172 ? -4.448   14.065  50.208  1.00 56.00  ? 379 TYR G CE1 1 
ATOM   10092 C CE2 . TYR G 1 172 ? -3.782   15.316  52.135  1.00 53.80  ? 379 TYR G CE2 1 
ATOM   10093 C CZ  . TYR G 1 172 ? -3.515   14.834  50.871  1.00 52.09  ? 379 TYR G CZ  1 
ATOM   10094 O OH  . TYR G 1 172 ? -2.322   15.128  50.269  1.00 48.52  ? 379 TYR G OH  1 
ATOM   10095 N N   . ASP G 1 173 ? -5.304   11.411  53.313  1.00 54.35  ? 380 ASP G N   1 
ATOM   10096 C CA  . ASP G 1 173 ? -4.073   10.935  53.945  1.00 57.42  ? 380 ASP G CA  1 
ATOM   10097 C C   . ASP G 1 173 ? -3.024   12.037  53.882  1.00 57.43  ? 380 ASP G C   1 
ATOM   10098 O O   . ASP G 1 173 ? -2.383   12.246  52.844  1.00 56.10  ? 380 ASP G O   1 
ATOM   10099 C CB  . ASP G 1 173 ? -3.587   9.671   53.253  1.00 54.97  ? 380 ASP G CB  1 
ATOM   10100 C CG  . ASP G 1 173 ? -2.192   9.306   53.647  1.00 59.81  ? 380 ASP G CG  1 
ATOM   10101 O OD1 . ASP G 1 173 ? -1.843   9.498   54.828  1.00 61.44  ? 380 ASP G OD1 1 
ATOM   10102 O OD2 . ASP G 1 173 ? -1.439   8.827   52.776  1.00 72.21  ? 380 ASP G OD2 1 
ATOM   10103 N N   . ALA G 1 174 ? -2.836   12.745  54.993  1.00 53.87  ? 381 ALA G N   1 
ATOM   10104 C CA  . ALA G 1 174 ? -1.967   13.915  54.954  1.00 58.81  ? 381 ALA G CA  1 
ATOM   10105 C C   . ALA G 1 174 ? -0.604   13.656  55.590  1.00 65.28  ? 381 ALA G C   1 
ATOM   10106 O O   . ALA G 1 174 ? -0.142   14.447  56.419  1.00 65.92  ? 381 ALA G O   1 
ATOM   10107 C CB  . ALA G 1 174 ? -2.648   15.099  55.648  1.00 60.90  ? 381 ALA G CB  1 
ATOM   10108 N N   . GLY G 1 175 ? 0.045    12.557  55.216  1.00 65.55  ? 382 GLY G N   1 
ATOM   10109 C CA  . GLY G 1 175 ? 1.397    12.301  55.697  1.00 73.78  ? 382 GLY G CA  1 
ATOM   10110 C C   . GLY G 1 175 ? 1.483    12.165  57.210  1.00 71.71  ? 382 GLY G C   1 
ATOM   10111 O O   . GLY G 1 175 ? 0.724    11.414  57.835  1.00 69.92  ? 382 GLY G O   1 
ATOM   10112 N N   . GLU G 1 176 ? 2.419    12.896  57.807  1.00 73.56  ? 383 GLU G N   1 
ATOM   10113 C CA  . GLU G 1 176 ? 2.658    12.793  59.268  1.00 76.90  ? 383 GLU G CA  1 
ATOM   10114 C C   . GLU G 1 176 ? 1.404    13.158  60.060  1.00 73.87  ? 383 GLU G C   1 
ATOM   10115 O O   . GLU G 1 176 ? 1.235    12.624  61.164  1.00 75.02  ? 383 GLU G O   1 
ATOM   10116 C CB  . GLU G 1 176 ? 3.814    13.714  59.647  1.00 84.33  ? 383 GLU G CB  1 
ATOM   10117 C CG  . GLU G 1 176 ? 5.144    13.274  59.070  1.00 87.11  ? 383 GLU G CG  1 
ATOM   10118 C CD  . GLU G 1 176 ? 5.687    14.187  57.987  1.00 91.56  ? 383 GLU G CD  1 
ATOM   10119 O OE1 . GLU G 1 176 ? 4.919    14.542  57.073  1.00 96.97  ? 383 GLU G OE1 1 
ATOM   10120 O OE2 . GLU G 1 176 ? 6.876    14.541  58.063  1.00 91.61  ? 383 GLU G OE2 1 
ATOM   10121 N N   . HIS G 1 177 ? 0.579    14.050  59.522  1.00 72.66  ? 384 HIS G N   1 
ATOM   10122 C CA  . HIS G 1 177 ? -0.658   14.469  60.230  1.00 75.63  ? 384 HIS G CA  1 
ATOM   10123 C C   . HIS G 1 177 ? -1.672   13.324  60.222  1.00 70.51  ? 384 HIS G C   1 
ATOM   10124 O O   . HIS G 1 177 ? -2.621   13.377  61.016  1.00 63.60  ? 384 HIS G O   1 
ATOM   10125 C CB  . HIS G 1 177 ? -1.212   15.744  59.593  1.00 73.41  ? 384 HIS G CB  1 
ATOM   10126 C CG  . HIS G 1 177 ? -0.251   16.879  59.591  1.00 80.00  ? 384 HIS G CG  1 
ATOM   10127 N ND1 . HIS G 1 177 ? -0.002   17.632  60.717  1.00 84.16  ? 384 HIS G ND1 1 
ATOM   10128 C CD2 . HIS G 1 177 ? 0.521    17.391  58.612  1.00 78.89  ? 384 HIS G CD2 1 
ATOM   10129 C CE1 . HIS G 1 177 ? 0.883    18.562  60.431  1.00 81.66  ? 384 HIS G CE1 1 
ATOM   10130 N NE2 . HIS G 1 177 ? 1.221    18.436  59.145  1.00 81.65  ? 384 HIS G NE2 1 
ATOM   10131 N N   . GLY G 1 178 ? -1.478   12.340  59.349  1.00 66.20  ? 385 GLY G N   1 
ATOM   10132 C CA  . GLY G 1 178 ? -2.366   11.167  59.310  1.00 60.61  ? 385 GLY G CA  1 
ATOM   10133 C C   . GLY G 1 178 ? -3.609   11.390  58.480  1.00 66.25  ? 385 GLY G C   1 
ATOM   10134 O O   . GLY G 1 178 ? -3.611   12.297  57.641  1.00 68.01  ? 385 GLY G O   1 
ATOM   10135 N N   . LEU G 1 179 ? -4.631   10.570  58.706  1.00 61.54  ? 386 LEU G N   1 
ATOM   10136 C CA  . LEU G 1 179 ? -5.903   10.713  57.963  1.00 60.36  ? 386 LEU G CA  1 
ATOM   10137 C C   . LEU G 1 179 ? -6.658   11.925  58.513  1.00 62.82  ? 386 LEU G C   1 
ATOM   10138 O O   . LEU G 1 179 ? -6.919   11.952  59.726  1.00 62.49  ? 386 LEU G O   1 
ATOM   10139 C CB  . LEU G 1 179 ? -6.691   9.409   58.093  1.00 61.52  ? 386 LEU G CB  1 
ATOM   10140 C CG  . LEU G 1 179 ? -6.750   8.556   56.829  1.00 65.16  ? 386 LEU G CG  1 
ATOM   10141 C CD1 . LEU G 1 179 ? -5.380   7.997   56.484  1.00 64.99  ? 386 LEU G CD1 1 
ATOM   10142 C CD2 . LEU G 1 179 ? -7.754   7.429   56.991  1.00 67.09  ? 386 LEU G CD2 1 
ATOM   10143 N N   . GLN G 1 180 ? -7.007   12.882  57.648  1.00 57.70  ? 387 GLN G N   1 
ATOM   10144 C CA  . GLN G 1 180 ? -7.631   14.141  58.116  1.00 57.83  ? 387 GLN G CA  1 
ATOM   10145 C C   . GLN G 1 180 ? -8.778   14.617  57.229  1.00 56.91  ? 387 GLN G C   1 
ATOM   10146 O O   . GLN G 1 180 ? -8.707   14.398  56.021  1.00 59.31  ? 387 GLN G O   1 
ATOM   10147 C CB  . GLN G 1 180 ? -6.583   15.252  58.075  1.00 58.11  ? 387 GLN G CB  1 
ATOM   10148 C CG  . GLN G 1 180 ? -5.386   15.058  58.991  1.00 58.29  ? 387 GLN G CG  1 
ATOM   10149 C CD  . GLN G 1 180 ? -5.654   15.571  60.382  1.00 62.54  ? 387 GLN G CD  1 
ATOM   10150 O OE1 . GLN G 1 180 ? -6.451   16.482  60.589  1.00 58.87  ? 387 GLN G OE1 1 
ATOM   10151 N NE2 . GLN G 1 180 ? -4.983   14.980  61.354  1.00 64.65  ? 387 GLN G NE2 1 
ATOM   10152 N N   . GLU G 1 181 ? -9.799   15.250  57.814  1.00 53.48  ? 388 GLU G N   1 
ATOM   10153 C CA  . GLU G 1 181 ? -10.853  15.899  57.046  1.00 58.99  ? 388 GLU G CA  1 
ATOM   10154 C C   . GLU G 1 181 ? -10.229  16.958  56.150  1.00 60.99  ? 388 GLU G C   1 
ATOM   10155 O O   . GLU G 1 181 ? -9.321   17.676  56.567  1.00 67.46  ? 388 GLU G O   1 
ATOM   10156 C CB  . GLU G 1 181 ? -11.890  16.537  57.977  1.00 59.29  ? 388 GLU G CB  1 
ATOM   10157 C CG  . GLU G 1 181 ? -12.360  15.642  59.123  1.00 71.92  ? 388 GLU G CG  1 
ATOM   10158 C CD  . GLU G 1 181 ? -13.619  16.164  59.833  1.00 82.98  ? 388 GLU G CD  1 
ATOM   10159 O OE1 . GLU G 1 181 ? -14.225  17.160  59.363  1.00 76.67  ? 388 GLU G OE1 1 
ATOM   10160 O OE2 . GLU G 1 181 ? -13.996  15.572  60.874  1.00 87.22  ? 388 GLU G OE2 1 
ATOM   10161 N N   . ALA G 1 182 ? -10.703  17.060  54.914  1.00 57.02  ? 389 ALA G N   1 
ATOM   10162 C CA  . ALA G 1 182 ? -10.064  17.958  53.964  1.00 57.34  ? 389 ALA G CA  1 
ATOM   10163 C C   . ALA G 1 182 ? -11.086  18.476  52.966  1.00 60.94  ? 389 ALA G C   1 
ATOM   10164 O O   . ALA G 1 182 ? -12.233  18.035  52.940  1.00 67.58  ? 389 ALA G O   1 
ATOM   10165 C CB  . ALA G 1 182 ? -8.922   17.264  53.227  1.00 55.92  ? 389 ALA G CB  1 
ATOM   10166 N N   . GLU G 1 183 ? -10.639  19.406  52.125  1.00 58.04  ? 390 GLU G N   1 
ATOM   10167 C CA  . GLU G 1 183 ? -11.497  19.957  51.054  1.00 61.45  ? 390 GLU G CA  1 
ATOM   10168 C C   . GLU G 1 183 ? -10.798  19.720  49.718  1.00 63.76  ? 390 GLU G C   1 
ATOM   10169 O O   . GLU G 1 183 ? -9.610   19.990  49.632  1.00 61.91  ? 390 GLU G O   1 
ATOM   10170 C CB  . GLU G 1 183 ? -11.680  21.459  51.227  1.00 66.49  ? 390 GLU G CB  1 
ATOM   10171 C CG  . GLU G 1 183 ? -12.665  21.846  52.308  1.00 73.71  ? 390 GLU G CG  1 
ATOM   10172 C CD  . GLU G 1 183 ? -13.091  23.303  52.259  1.00 83.90  ? 390 GLU G CD  1 
ATOM   10173 O OE1 . GLU G 1 183 ? -14.214  23.602  52.698  1.00 86.60  ? 390 GLU G OE1 1 
ATOM   10174 O OE2 . GLU G 1 183 ? -12.297  24.134  51.782  1.00 85.87  ? 390 GLU G OE2 1 
ATOM   10175 N N   . LYS G 1 184 ? -11.539  19.228  48.727  1.00 56.97  ? 391 LYS G N   1 
ATOM   10176 C CA  . LYS G 1 184 ? -10.953  18.952  47.398  1.00 52.14  ? 391 LYS G CA  1 
ATOM   10177 C C   . LYS G 1 184 ? -11.676  19.765  46.335  1.00 56.00  ? 391 LYS G C   1 
ATOM   10178 O O   . LYS G 1 184 ? -12.907  19.736  46.311  1.00 55.96  ? 391 LYS G O   1 
ATOM   10179 C CB  . LYS G 1 184 ? -11.042  17.466  47.051  1.00 54.64  ? 391 LYS G CB  1 
ATOM   10180 C CG  . LYS G 1 184 ? -10.394  17.064  45.733  1.00 56.52  ? 391 LYS G CG  1 
ATOM   10181 C CD  . LYS G 1 184 ? -10.144  15.582  45.615  1.00 53.96  ? 391 LYS G CD  1 
ATOM   10182 C CE  . LYS G 1 184 ? -9.529   15.196  44.289  1.00 51.69  ? 391 LYS G CE  1 
ATOM   10183 N NZ  . LYS G 1 184 ? -10.545  15.108  43.216  1.00 52.82  ? 391 LYS G NZ  1 
ATOM   10184 N N   . GLY G 1 185 ? -10.923  20.467  45.496  1.00 48.02  ? 392 GLY G N   1 
ATOM   10185 C CA  . GLY G 1 185 ? -11.520  21.179  44.396  1.00 40.42  ? 392 GLY G CA  1 
ATOM   10186 C C   . GLY G 1 185 ? -10.738  20.914  43.138  1.00 48.18  ? 392 GLY G C   1 
ATOM   10187 O O   . GLY G 1 185 ? -9.513   20.836  43.204  1.00 56.41  ? 392 GLY G O   1 
ATOM   10188 N N   . VAL G 1 186 ? -11.416  20.736  42.004  1.00 50.39  ? 393 VAL G N   1 
ATOM   10189 C CA  . VAL G 1 186 ? -10.770  20.621  40.701  1.00 50.37  ? 393 VAL G CA  1 
ATOM   10190 C C   . VAL G 1 186 ? -11.019  21.897  39.898  1.00 58.29  ? 393 VAL G C   1 
ATOM   10191 O O   . VAL G 1 186 ? -12.012  22.608  40.101  1.00 65.19  ? 393 VAL G O   1 
ATOM   10192 C CB  . VAL G 1 186 ? -11.273  19.380  39.940  1.00 50.70  ? 393 VAL G CB  1 
ATOM   10193 C CG1 . VAL G 1 186 ? -10.409  19.103  38.705  1.00 51.90  ? 393 VAL G CG1 1 
ATOM   10194 C CG2 . VAL G 1 186 ? -11.269  18.196  40.875  1.00 52.59  ? 393 VAL G CG2 1 
ATOM   10195 N N   . LYS G 1 187 ? -10.063  22.231  39.035  1.00 54.93  ? 394 LYS G N   1 
ATOM   10196 C CA  . LYS G 1 187 ? -10.209  23.304  38.062  1.00 54.50  ? 394 LYS G CA  1 
ATOM   10197 C C   . LYS G 1 187 ? -9.413   22.878  36.850  1.00 53.76  ? 394 LYS G C   1 
ATOM   10198 O O   . LYS G 1 187 ? -8.631   21.932  36.916  1.00 61.55  ? 394 LYS G O   1 
ATOM   10199 C CB  . LYS G 1 187 ? -9.723   24.661  38.594  1.00 55.99  ? 394 LYS G CB  1 
ATOM   10200 C CG  . LYS G 1 187 ? -10.671  25.378  39.560  1.00 56.21  ? 394 LYS G CG  1 
ATOM   10201 C CD  . LYS G 1 187 ? -11.619  26.323  38.803  1.00 62.60  ? 394 LYS G CD  1 
ATOM   10202 C CE  . LYS G 1 187 ? -11.689  27.737  39.404  1.00 62.24  ? 394 LYS G CE  1 
ATOM   10203 N NZ  . LYS G 1 187 ? -12.673  27.842  40.526  1.00 68.94  ? 394 LYS G NZ  1 
ATOM   10204 N N   . PHE G 1 188 ? -9.631   23.550  35.728  1.00 55.87  ? 395 PHE G N   1 
ATOM   10205 C CA  . PHE G 1 188 ? -8.953   23.193  34.485  1.00 55.13  ? 395 PHE G CA  1 
ATOM   10206 C C   . PHE G 1 188 ? -7.779   24.139  34.262  1.00 56.54  ? 395 PHE G C   1 
ATOM   10207 O O   . PHE G 1 188 ? -7.906   25.351  34.463  1.00 56.09  ? 395 PHE G O   1 
ATOM   10208 C CB  . PHE G 1 188 ? -9.920   23.232  33.302  1.00 55.50  ? 395 PHE G CB  1 
ATOM   10209 C CG  . PHE G 1 188 ? -10.923  22.115  33.313  1.00 61.34  ? 395 PHE G CG  1 
ATOM   10210 C CD1 . PHE G 1 188 ? -12.027  22.160  34.158  1.00 58.93  ? 395 PHE G CD1 1 
ATOM   10211 C CD2 . PHE G 1 188 ? -10.762  21.013  32.487  1.00 60.10  ? 395 PHE G CD2 1 
ATOM   10212 C CE1 . PHE G 1 188 ? -12.951  21.118  34.187  1.00 57.65  ? 395 PHE G CE1 1 
ATOM   10213 C CE2 . PHE G 1 188 ? -11.679  19.981  32.504  1.00 54.98  ? 395 PHE G CE2 1 
ATOM   10214 C CZ  . PHE G 1 188 ? -12.776  20.029  33.359  1.00 57.29  ? 395 PHE G CZ  1 
ATOM   10215 N N   . LEU G 1 189 ? -6.616   23.605  33.913  1.00 51.27  ? 396 LEU G N   1 
ATOM   10216 C CA  . LEU G 1 189 ? -5.474   24.499  33.617  1.00 52.55  ? 396 LEU G CA  1 
ATOM   10217 C C   . LEU G 1 189 ? -5.607   24.940  32.173  1.00 51.29  ? 396 LEU G C   1 
ATOM   10218 O O   . LEU G 1 189 ? -5.539   26.148  31.925  1.00 55.04  ? 396 LEU G O   1 
ATOM   10219 C CB  . LEU G 1 189 ? -4.176   23.732  33.852  1.00 52.95  ? 396 LEU G CB  1 
ATOM   10220 C CG  . LEU G 1 189 ? -3.620   23.813  35.268  1.00 56.47  ? 396 LEU G CG  1 
ATOM   10221 C CD1 . LEU G 1 189 ? -2.185   23.324  35.301  1.00 54.08  ? 396 LEU G CD1 1 
ATOM   10222 C CD2 . LEU G 1 189 ? -3.709   25.235  35.797  1.00 57.05  ? 396 LEU G CD2 1 
ATOM   10223 N N   . THR G 1 190 ? -5.765   23.985  31.269  1.00 49.69  ? 397 THR G N   1 
ATOM   10224 C CA  . THR G 1 190 ? -5.973   24.255  29.870  1.00 52.26  ? 397 THR G CA  1 
ATOM   10225 C C   . THR G 1 190 ? -7.208   23.493  29.417  1.00 62.74  ? 397 THR G C   1 
ATOM   10226 O O   . THR G 1 190 ? -7.805   22.717  30.173  1.00 64.48  ? 397 THR G O   1 
ATOM   10227 C CB  . THR G 1 190 ? -4.751   23.865  29.050  1.00 51.76  ? 397 THR G CB  1 
ATOM   10228 O OG1 . THR G 1 190 ? -4.655   22.438  28.979  1.00 57.59  ? 397 THR G OG1 1 
ATOM   10229 C CG2 . THR G 1 190 ? -3.513   24.420  29.708  1.00 50.57  ? 397 THR G CG2 1 
ATOM   10230 N N   . LEU G 1 191 ? -7.664   23.842  28.217  1.00 62.52  ? 398 LEU G N   1 
ATOM   10231 C CA  . LEU G 1 191 ? -8.828   23.172  27.600  1.00 57.62  ? 398 LEU G CA  1 
ATOM   10232 C C   . LEU G 1 191 ? -8.396   22.904  26.166  1.00 55.13  ? 398 LEU G C   1 
ATOM   10233 O O   . LEU G 1 191 ? -7.980   23.853  25.492  1.00 63.21  ? 398 LEU G O   1 
ATOM   10234 C CB  . LEU G 1 191 ? -10.051  24.085  27.679  1.00 57.25  ? 398 LEU G CB  1 
ATOM   10235 C CG  . LEU G 1 191 ? -10.879  23.961  28.956  1.00 59.45  ? 398 LEU G CG  1 
ATOM   10236 C CD1 . LEU G 1 191 ? -11.801  25.153  29.118  1.00 57.26  ? 398 LEU G CD1 1 
ATOM   10237 C CD2 . LEU G 1 191 ? -11.678  22.672  28.961  1.00 65.84  ? 398 LEU G CD2 1 
ATOM   10238 N N   . PRO G 1 192 ? -8.482   21.662  25.665  1.00 59.93  ? 399 PRO G N   1 
ATOM   10239 C CA  . PRO G 1 192 ? -7.927   21.305  24.345  1.00 66.11  ? 399 PRO G CA  1 
ATOM   10240 C C   . PRO G 1 192 ? -8.712   21.947  23.210  1.00 70.81  ? 399 PRO G C   1 
ATOM   10241 O O   . PRO G 1 192 ? -9.869   22.380  23.386  1.00 65.76  ? 399 PRO G O   1 
ATOM   10242 C CB  . PRO G 1 192 ? -8.040   19.770  24.313  1.00 60.66  ? 399 PRO G CB  1 
ATOM   10243 C CG  . PRO G 1 192 ? -9.144   19.459  25.251  1.00 63.08  ? 399 PRO G CG  1 
ATOM   10244 C CD  . PRO G 1 192 ? -9.124   20.518  26.336  1.00 60.82  ? 399 PRO G CD  1 
ATOM   10245 N N   . PRO G 1 193 ? -8.090   22.062  22.028  1.00 67.06  ? 400 PRO G N   1 
ATOM   10246 C CA  . PRO G 1 193 ? -8.807   22.604  20.862  1.00 62.44  ? 400 PRO G CA  1 
ATOM   10247 C C   . PRO G 1 193 ? -10.099  21.863  20.567  1.00 66.02  ? 400 PRO G C   1 
ATOM   10248 O O   . PRO G 1 193 ? -11.119  22.484  20.236  1.00 63.11  ? 400 PRO G O   1 
ATOM   10249 C CB  . PRO G 1 193 ? -7.799   22.428  19.724  1.00 65.01  ? 400 PRO G CB  1 
ATOM   10250 C CG  . PRO G 1 193 ? -6.461   22.184  20.381  1.00 61.18  ? 400 PRO G CG  1 
ATOM   10251 C CD  . PRO G 1 193 ? -6.720   21.612  21.711  1.00 65.10  ? 400 PRO G CD  1 
ATOM   10252 N N   . VAL G 1 194 ? -10.063  20.537  20.680  1.00 66.64  ? 401 VAL G N   1 
ATOM   10253 C CA  . VAL G 1 194 ? -11.222  19.666  20.528  1.00 65.61  ? 401 VAL G CA  1 
ATOM   10254 C C   . VAL G 1 194 ? -11.557  19.096  21.904  1.00 63.12  ? 401 VAL G C   1 
ATOM   10255 O O   . VAL G 1 194 ? -10.776  18.320  22.464  1.00 65.74  ? 401 VAL G O   1 
ATOM   10256 C CB  . VAL G 1 194 ? -10.937  18.546  19.524  1.00 60.98  ? 401 VAL G CB  1 
ATOM   10257 C CG1 . VAL G 1 194 ? -12.158  17.638  19.359  1.00 63.35  ? 401 VAL G CG1 1 
ATOM   10258 C CG2 . VAL G 1 194 ? -10.502  19.138  18.198  1.00 63.35  ? 401 VAL G CG2 1 
ATOM   10259 N N   . LEU G 1 195 ? -12.739  19.443  22.403  1.00 57.22  ? 402 LEU G N   1 
ATOM   10260 C CA  . LEU G 1 195 ? -13.183  18.938  23.719  1.00 63.07  ? 402 LEU G CA  1 
ATOM   10261 C C   . LEU G 1 195 ? -14.141  17.766  23.528  1.00 67.60  ? 402 LEU G C   1 
ATOM   10262 O O   . LEU G 1 195 ? -15.166  17.950  22.866  1.00 65.01  ? 402 LEU G O   1 
ATOM   10263 C CB  . LEU G 1 195 ? -13.888  20.076  24.458  1.00 56.79  ? 402 LEU G CB  1 
ATOM   10264 C CG  . LEU G 1 195 ? -13.305  20.463  25.812  1.00 63.90  ? 402 LEU G CG  1 
ATOM   10265 C CD1 . LEU G 1 195 ? -14.378  21.087  26.686  1.00 58.90  ? 402 LEU G CD1 1 
ATOM   10266 C CD2 . LEU G 1 195 ? -12.696  19.257  26.499  1.00 66.46  ? 402 LEU G CD2 1 
ATOM   10267 N N   . HIS G 1 196 ? -13.800  16.601  24.075  1.00 30.00  ? 403 HIS G N   1 
ATOM   10268 C CA  . HIS G 1 196 ? -14.743  15.460  24.059  1.00 30.00  ? 403 HIS G CA  1 
ATOM   10269 C C   . HIS G 1 196 ? -15.472  15.484  25.400  1.00 30.00  ? 403 HIS G C   1 
ATOM   10270 O O   . HIS G 1 196 ? -14.799  15.580  26.429  1.00 30.00  ? 403 HIS G O   1 
ATOM   10271 C CB  . HIS G 1 196 ? -13.999  14.147  23.831  1.00 30.00  ? 403 HIS G CB  1 
ATOM   10272 C CG  . HIS G 1 196 ? -13.591  13.886  22.425  1.00 30.00  ? 403 HIS G CG  1 
ATOM   10273 N ND1 . HIS G 1 196 ? -13.822  14.780  21.408  1.00 30.00  ? 403 HIS G ND1 1 
ATOM   10274 C CD2 . HIS G 1 196 ? -12.963  12.832  21.871  1.00 30.00  ? 403 HIS G CD2 1 
ATOM   10275 C CE1 . HIS G 1 196 ? -13.362  14.282  20.282  1.00 30.00  ? 403 HIS G CE1 1 
ATOM   10276 N NE2 . HIS G 1 196 ? -12.831  13.090  20.539  1.00 30.00  ? 403 HIS G NE2 1 
ATOM   10277 N N   . LEU G 1 197 ? -16.799  15.453  25.381  1.00 50.33  ? 404 LEU G N   1 
ATOM   10278 C CA  . LEU G 1 197 ? -17.581  15.543  26.637  1.00 57.77  ? 404 LEU G CA  1 
ATOM   10279 C C   . LEU G 1 197 ? -18.441  14.290  26.785  1.00 65.06  ? 404 LEU G C   1 
ATOM   10280 O O   . LEU G 1 197 ? -19.365  14.120  25.992  1.00 63.70  ? 404 LEU G O   1 
ATOM   10281 C CB  . LEU G 1 197 ? -18.434  16.814  26.611  1.00 60.01  ? 404 LEU G CB  1 
ATOM   10282 C CG  . LEU G 1 197 ? -17.666  18.132  26.656  1.00 59.00  ? 404 LEU G CG  1 
ATOM   10283 C CD1 . LEU G 1 197 ? -18.620  19.307  26.589  1.00 56.55  ? 404 LEU G CD1 1 
ATOM   10284 C CD2 . LEU G 1 197 ? -16.829  18.217  27.914  1.00 54.53  ? 404 LEU G CD2 1 
ATOM   10285 N N   . GLN G 1 198 ? -18.096  13.442  27.756  1.00 58.35  ? 405 GLN G N   1 
ATOM   10286 C CA  . GLN G 1 198 ? -18.884  12.218  28.031  1.00 56.84  ? 405 GLN G CA  1 
ATOM   10287 C C   . GLN G 1 198 ? -19.921  12.538  29.093  1.00 59.00  ? 405 GLN G C   1 
ATOM   10288 O O   . GLN G 1 198 ? -19.542  12.905  30.211  1.00 54.41  ? 405 GLN G O   1 
ATOM   10289 C CB  . GLN G 1 198 ? -18.018  11.057  28.508  1.00 52.35  ? 405 GLN G CB  1 
ATOM   10290 C CG  . GLN G 1 198 ? -18.834  9.839   28.910  1.00 52.80  ? 405 GLN G CG  1 
ATOM   10291 C CD  . GLN G 1 198 ? -17.982  8.720   29.446  1.00 58.30  ? 405 GLN G CD  1 
ATOM   10292 O OE1 . GLN G 1 198 ? -16.880  8.931   29.937  1.00 58.03  ? 405 GLN G OE1 1 
ATOM   10293 N NE2 . GLN G 1 198 ? -18.487  7.506   29.333  1.00 60.27  ? 405 GLN G NE2 1 
ATOM   10294 N N   . LEU G 1 199 ? -21.184  12.409  28.723  1.00 60.19  ? 406 LEU G N   1 
ATOM   10295 C CA  . LEU G 1 199 ? -22.286  12.650  29.644  1.00 65.49  ? 406 LEU G CA  1 
ATOM   10296 C C   . LEU G 1 199 ? -22.510  11.420  30.516  1.00 61.61  ? 406 LEU G C   1 
ATOM   10297 O O   . LEU G 1 199 ? -22.638  10.302  30.003  1.00 60.90  ? 406 LEU G O   1 
ATOM   10298 C CB  . LEU G 1 199 ? -23.548  13.006  28.858  1.00 67.53  ? 406 LEU G CB  1 
ATOM   10299 C CG  . LEU G 1 199 ? -23.352  14.295  28.049  1.00 68.87  ? 406 LEU G CG  1 
ATOM   10300 C CD1 . LEU G 1 199 ? -24.671  14.890  27.559  1.00 68.41  ? 406 LEU G CD1 1 
ATOM   10301 C CD2 . LEU G 1 199 ? -22.586  15.311  28.904  1.00 57.38  ? 406 LEU G CD2 1 
ATOM   10302 N N   . MET G 1 200 ? -22.528  11.628  31.836  1.00 49.78  ? 407 MET G N   1 
ATOM   10303 C CA  . MET G 1 200 ? -22.647  10.538  32.803  1.00 59.77  ? 407 MET G CA  1 
ATOM   10304 C C   . MET G 1 200 ? -24.111  10.101  32.929  1.00 64.47  ? 407 MET G C   1 
ATOM   10305 O O   . MET G 1 200 ? -24.761  10.293  33.961  1.00 61.75  ? 407 MET G O   1 
ATOM   10306 C CB  . MET G 1 200 ? -22.091  10.974  34.148  1.00 61.73  ? 407 MET G CB  1 
ATOM   10307 C CG  . MET G 1 200 ? -20.589  11.237  34.147  1.00 65.01  ? 407 MET G CG  1 
ATOM   10308 S SD  . MET G 1 200 ? -19.655  9.696   34.134  1.00 70.74  ? 407 MET G SD  1 
ATOM   10309 C CE  . MET G 1 200 ? -19.710  9.329   35.887  1.00 61.41  ? 407 MET G CE  1 
ATOM   10310 N N   . ARG G 1 201 ? -24.619  9.491   31.853  1.00 58.61  ? 408 ARG G N   1 
ATOM   10311 C CA  . ARG G 1 201 ? -26.037  9.128   31.725  1.00 62.05  ? 408 ARG G CA  1 
ATOM   10312 C C   . ARG G 1 201 ? -26.276  7.683   32.150  1.00 65.57  ? 408 ARG G C   1 
ATOM   10313 O O   . ARG G 1 201 ? -26.908  6.892   31.450  1.00 60.13  ? 408 ARG G O   1 
ATOM   10314 C CB  . ARG G 1 201 ? -26.521  9.366   30.295  1.00 56.13  ? 408 ARG G CB  1 
ATOM   10315 N N   . PHE G 1 202 ? -25.690  7.329   33.290  1.00 61.98  ? 409 PHE G N   1 
ATOM   10316 C CA  . PHE G 1 202 ? -25.841  5.960   33.836  1.00 63.70  ? 409 PHE G CA  1 
ATOM   10317 C C   . PHE G 1 202 ? -25.750  6.017   35.361  1.00 59.90  ? 409 PHE G C   1 
ATOM   10318 O O   . PHE G 1 202 ? -25.102  6.926   35.894  1.00 62.52  ? 409 PHE G O   1 
ATOM   10319 C CB  . PHE G 1 202 ? -24.800  4.995   33.259  1.00 64.16  ? 409 PHE G CB  1 
ATOM   10320 C CG  . PHE G 1 202 ? -23.491  5.581   32.797  1.00 60.63  ? 409 PHE G CG  1 
ATOM   10321 C CD1 . PHE G 1 202 ? -22.604  6.152   33.692  1.00 61.59  ? 409 PHE G CD1 1 
ATOM   10322 C CD2 . PHE G 1 202 ? -23.130  5.520   31.463  1.00 57.17  ? 409 PHE G CD2 1 
ATOM   10323 C CE1 . PHE G 1 202 ? -21.400  6.678   33.257  1.00 63.82  ? 409 PHE G CE1 1 
ATOM   10324 C CE2 . PHE G 1 202 ? -21.924  6.045   31.032  1.00 56.83  ? 409 PHE G CE2 1 
ATOM   10325 C CZ  . PHE G 1 202 ? -21.062  6.626   31.928  1.00 54.76  ? 409 PHE G CZ  1 
ATOM   10326 N N   . MET G 1 203 ? -26.395  5.068   36.034  1.00 64.94  ? 410 MET G N   1 
ATOM   10327 C CA  . MET G 1 203 ? -26.327  4.999   37.512  1.00 73.85  ? 410 MET G CA  1 
ATOM   10328 C C   . MET G 1 203 ? -26.608  3.566   37.960  1.00 79.41  ? 410 MET G C   1 
ATOM   10329 O O   . MET G 1 203 ? -27.727  3.092   37.731  1.00 73.00  ? 410 MET G O   1 
ATOM   10330 C CB  . MET G 1 203 ? -27.370  5.912   38.154  1.00 68.45  ? 410 MET G CB  1 
ATOM   10331 N N   . TYR G 1 204 ? -25.616  2.906   38.558  1.00 86.93  ? 411 TYR G N   1 
ATOM   10332 C CA  . TYR G 1 204 ? -25.839  1.547   39.109  1.00 89.37  ? 411 TYR G CA  1 
ATOM   10333 C C   . TYR G 1 204 ? -26.489  1.711   40.478  1.00 95.48  ? 411 TYR G C   1 
ATOM   10334 O O   . TYR G 1 204 ? -25.788  2.019   41.453  1.00 96.85  ? 411 TYR G O   1 
ATOM   10335 C CB  . TYR G 1 204 ? -24.542  0.738   39.187  1.00 82.08  ? 411 TYR G CB  1 
ATOM   10336 C CG  . TYR G 1 204 ? -24.679  -0.613  39.842  1.00 91.64  ? 411 TYR G CG  1 
ATOM   10337 C CD1 . TYR G 1 204 ? -25.311  -1.657  39.191  1.00 97.75  ? 411 TYR G CD1 1 
ATOM   10338 C CD2 . TYR G 1 204 ? -24.182  -0.849  41.112  1.00 82.76  ? 411 TYR G CD2 1 
ATOM   10339 C CE1 . TYR G 1 204 ? -25.445  -2.901  39.784  1.00 95.80  ? 411 TYR G CE1 1 
ATOM   10340 C CE2 . TYR G 1 204 ? -24.317  -2.083  41.724  1.00 82.70  ? 411 TYR G CE2 1 
ATOM   10341 C CZ  . TYR G 1 204 ? -24.950  -3.114  41.056  1.00 89.31  ? 411 TYR G CZ  1 
ATOM   10342 O OH  . TYR G 1 204 ? -25.082  -4.338  41.641  1.00 94.56  ? 411 TYR G OH  1 
ATOM   10343 N N   . ASP G 1 205 ? -27.807  1.530   40.533  1.00 98.96  ? 412 ASP G N   1 
ATOM   10344 C CA  . ASP G 1 205 ? -28.513  1.547   41.837  1.00 107.58 ? 412 ASP G CA  1 
ATOM   10345 C C   . ASP G 1 205 ? -28.150  0.239   42.550  1.00 108.84 ? 412 ASP G C   1 
ATOM   10346 O O   . ASP G 1 205 ? -27.935  -0.768  41.853  1.00 106.34 ? 412 ASP G O   1 
ATOM   10347 C CB  . ASP G 1 205 ? -30.016  1.779   41.630  1.00 103.24 ? 412 ASP G CB  1 
ATOM   10348 C CG  . ASP G 1 205 ? -30.922  0.674   42.148  1.00 108.47 ? 412 ASP G CG  1 
ATOM   10349 O OD1 . ASP G 1 205 ? -31.329  0.752   43.322  1.00 108.52 ? 412 ASP G OD1 1 
ATOM   10350 O OD2 . ASP G 1 205 ? -31.230  -0.245  41.366  1.00 108.90 ? 412 ASP G OD2 1 
ATOM   10351 N N   . PRO G 1 206 ? -28.036  0.220   43.894  1.00 108.87 ? 413 PRO G N   1 
ATOM   10352 C CA  . PRO G 1 206 ? -27.657  -0.986  44.631  1.00 106.74 ? 413 PRO G CA  1 
ATOM   10353 C C   . PRO G 1 206 ? -28.679  -2.122  44.506  1.00 114.52 ? 413 PRO G C   1 
ATOM   10354 O O   . PRO G 1 206 ? -29.339  -2.386  45.495  1.00 117.14 ? 413 PRO G O   1 
ATOM   10355 C CB  . PRO G 1 206 ? -27.601  -0.499  46.086  1.00 113.05 ? 413 PRO G CB  1 
ATOM   10356 C CG  . PRO G 1 206 ? -27.387  0.987   45.980  1.00 114.95 ? 413 PRO G CG  1 
ATOM   10357 C CD  . PRO G 1 206 ? -28.205  1.378   44.772  1.00 113.15 ? 413 PRO G CD  1 
ATOM   10358 N N   . GLN G 1 207 ? -28.736  -2.791  43.351  1.00 110.47 ? 414 GLN G N   1 
ATOM   10359 C CA  . GLN G 1 207 ? -29.699  -3.887  43.075  1.00 104.22 ? 414 GLN G CA  1 
ATOM   10360 C C   . GLN G 1 207 ? -29.638  -4.178  41.583  1.00 106.84 ? 414 GLN G C   1 
ATOM   10361 O O   . GLN G 1 207 ? -29.845  -5.345  41.214  1.00 104.78 ? 414 GLN G O   1 
ATOM   10362 C CB  . GLN G 1 207 ? -31.147  -3.478  43.325  1.00 98.82  ? 414 GLN G CB  1 
ATOM   10363 N N   . THR G 1 208 ? -29.357  -3.156  40.763  1.00 30.00  ? 415 THR G N   1 
ATOM   10364 C CA  . THR G 1 208 ? -29.221  -3.314  39.289  1.00 30.00  ? 415 THR G CA  1 
ATOM   10365 C C   . THR G 1 208 ? -28.684  -2.008  38.690  1.00 30.00  ? 415 THR G C   1 
ATOM   10366 O O   . THR G 1 208 ? -29.118  -0.938  39.149  1.00 30.00  ? 415 THR G O   1 
ATOM   10367 C CB  . THR G 1 208 ? -30.542  -3.706  38.616  1.00 30.00  ? 415 THR G CB  1 
ATOM   10368 O OG1 . THR G 1 208 ? -30.596  -5.131  38.556  1.00 30.00  ? 415 THR G OG1 1 
ATOM   10369 C CG2 . THR G 1 208 ? -30.697  -3.157  37.214  1.00 30.00  ? 415 THR G CG2 1 
ATOM   10370 N N   . ILE G 1 212 ? -28.606  0.601   34.882  1.00 75.34  ? 419 ILE G N   1 
ATOM   10371 C CA  . ILE G 1 212 ? -29.642  1.606   34.620  1.00 79.31  ? 419 ILE G CA  1 
ATOM   10372 C C   . ILE G 1 212 ? -29.084  2.832   33.884  1.00 66.63  ? 419 ILE G C   1 
ATOM   10373 O O   . ILE G 1 212 ? -28.159  3.467   34.356  1.00 67.78  ? 419 ILE G O   1 
ATOM   10374 C CB  . ILE G 1 212 ? -30.327  2.034   35.937  1.00 76.45  ? 419 ILE G CB  1 
ATOM   10375 C CG1 . ILE G 1 212 ? -31.146  0.873   36.507  1.00 82.06  ? 419 ILE G CG1 1 
ATOM   10376 C CG2 . ILE G 1 212 ? -31.196  3.257   35.733  1.00 68.47  ? 419 ILE G CG2 1 
ATOM   10377 C CD1 . ILE G 1 212 ? -32.612  0.874   36.112  1.00 81.41  ? 419 ILE G CD1 1 
ATOM   10378 N N   . LYS G 1 213 ? -29.664  3.161   32.729  1.00 70.12  ? 420 LYS G N   1 
ATOM   10379 C CA  . LYS G 1 213 ? -29.295  4.359   31.978  1.00 68.87  ? 420 LYS G CA  1 
ATOM   10380 C C   . LYS G 1 213 ? -30.138  5.550   32.420  1.00 68.60  ? 420 LYS G C   1 
ATOM   10381 O O   . LYS G 1 213 ? -31.345  5.422   32.632  1.00 70.00  ? 420 LYS G O   1 
ATOM   10382 C CB  . LYS G 1 213 ? -29.467  4.140   30.469  1.00 63.43  ? 420 LYS G CB  1 
ATOM   10383 C CG  . LYS G 1 213 ? -29.587  5.424   29.687  1.00 64.86  ? 420 LYS G CG  1 
ATOM   10384 C CD  . LYS G 1 213 ? -29.795  5.205   28.215  1.00 70.13  ? 420 LYS G CD  1 
ATOM   10385 C CE  . LYS G 1 213 ? -29.460  6.468   27.463  1.00 69.26  ? 420 LYS G CE  1 
ATOM   10386 N NZ  . LYS G 1 213 ? -30.111  6.507   26.147  1.00 71.30  ? 420 LYS G NZ  1 
ATOM   10387 N N   . ILE G 1 214 ? -29.495  6.704   32.634  1.00 70.60  ? 421 ILE G N   1 
ATOM   10388 C CA  . ILE G 1 214 ? -30.213  7.955   33.026  1.00 69.85  ? 421 ILE G CA  1 
ATOM   10389 C C   . ILE G 1 214 ? -30.727  8.643   31.756  1.00 74.79  ? 421 ILE G C   1 
ATOM   10390 O O   . ILE G 1 214 ? -29.898  9.060   30.934  1.00 75.18  ? 421 ILE G O   1 
ATOM   10391 C CB  . ILE G 1 214 ? -29.298  8.871   33.859  1.00 62.40  ? 421 ILE G CB  1 
ATOM   10392 C CG1 . ILE G 1 214 ? -28.882  8.207   35.173  1.00 64.77  ? 421 ILE G CG1 1 
ATOM   10393 C CG2 . ILE G 1 214 ? -29.940  10.228  34.096  1.00 69.17  ? 421 ILE G CG2 1 
ATOM   10394 C CD1 . ILE G 1 214 ? -29.687  8.647   36.370  1.00 71.86  ? 421 ILE G CD1 1 
ATOM   10395 N N   . ASN G 1 215 ? -32.048  8.752   31.604  1.00 75.05  ? 422 ASN G N   1 
ATOM   10396 C CA  . ASN G 1 215 ? -32.647  9.335   30.373  1.00 79.94  ? 422 ASN G CA  1 
ATOM   10397 C C   . ASN G 1 215 ? -33.243  10.707  30.688  1.00 75.54  ? 422 ASN G C   1 
ATOM   10398 O O   . ASN G 1 215 ? -34.059  11.186  29.888  1.00 70.58  ? 422 ASN G O   1 
ATOM   10399 C CB  . ASN G 1 215 ? -33.690  8.387   29.781  1.00 74.59  ? 422 ASN G CB  1 
ATOM   10400 C CG  . ASN G 1 215 ? -33.081  7.177   29.111  1.00 77.84  ? 422 ASN G CG  1 
ATOM   10401 O OD1 . ASN G 1 215 ? -32.528  7.286   28.024  1.00 77.06  ? 422 ASN G OD1 1 
ATOM   10402 N ND2 . ASN G 1 215 ? -33.184  6.023   29.747  1.00 79.95  ? 422 ASN G ND2 1 
ATOM   10403 N N   . ASP G 1 216 ? -32.812  11.329  31.783  1.00 73.28  ? 423 ASP G N   1 
ATOM   10404 C CA  . ASP G 1 216 ? -33.361  12.633  32.228  1.00 68.72  ? 423 ASP G CA  1 
ATOM   10405 C C   . ASP G 1 216 ? -33.002  13.754  31.246  1.00 73.87  ? 423 ASP G C   1 
ATOM   10406 O O   . ASP G 1 216 ? -32.160  13.534  30.361  1.00 74.68  ? 423 ASP G O   1 
ATOM   10407 C CB  . ASP G 1 216 ? -32.890  12.934  33.652  1.00 71.22  ? 423 ASP G CB  1 
ATOM   10408 C CG  . ASP G 1 216 ? -33.377  11.945  34.695  1.00 73.07  ? 423 ASP G CG  1 
ATOM   10409 O OD1 . ASP G 1 216 ? -34.195  11.072  34.349  1.00 84.04  ? 423 ASP G OD1 1 
ATOM   10410 O OD2 . ASP G 1 216 ? -32.933  12.059  35.850  1.00 72.20  ? 423 ASP G OD2 1 
ATOM   10411 N N   . ARG G 1 217 ? -33.602  14.931  31.426  1.00 72.44  ? 424 ARG G N   1 
ATOM   10412 C CA  . ARG G 1 217 ? -33.369  16.063  30.493  1.00 78.20  ? 424 ARG G CA  1 
ATOM   10413 C C   . ARG G 1 217 ? -32.031  16.736  30.788  1.00 78.14  ? 424 ARG G C   1 
ATOM   10414 O O   . ARG G 1 217 ? -31.863  17.255  31.905  1.00 77.80  ? 424 ARG G O   1 
ATOM   10415 C CB  . ARG G 1 217 ? -34.497  17.093  30.596  1.00 76.64  ? 424 ARG G CB  1 
ATOM   10416 N N   . PHE G 1 218 ? -31.128  16.747  29.807  1.00 74.77  ? 425 PHE G N   1 
ATOM   10417 C CA  . PHE G 1 218 ? -29.851  17.430  29.991  1.00 76.74  ? 425 PHE G CA  1 
ATOM   10418 C C   . PHE G 1 218 ? -29.596  18.427  28.865  1.00 74.88  ? 425 PHE G C   1 
ATOM   10419 O O   . PHE G 1 218 ? -29.418  18.040  27.699  1.00 65.22  ? 425 PHE G O   1 
ATOM   10420 C CB  . PHE G 1 218 ? -28.685  16.453  30.098  1.00 73.79  ? 425 PHE G CB  1 
ATOM   10421 C CG  . PHE G 1 218 ? -27.456  17.089  30.658  1.00 70.83  ? 425 PHE G CG  1 
ATOM   10422 C CD1 . PHE G 1 218 ? -27.370  17.357  32.023  1.00 72.65  ? 425 PHE G CD1 1 
ATOM   10423 C CD2 . PHE G 1 218 ? -26.418  17.481  29.821  1.00 61.26  ? 425 PHE G CD2 1 
ATOM   10424 C CE1 . PHE G 1 218 ? -26.255  17.971  32.553  1.00 70.37  ? 425 PHE G CE1 1 
ATOM   10425 C CE2 . PHE G 1 218 ? -25.303  18.093  30.333  1.00 68.04  ? 425 PHE G CE2 1 
ATOM   10426 C CZ  . PHE G 1 218 ? -25.215  18.341  31.703  1.00 72.74  ? 425 PHE G CZ  1 
ATOM   10427 N N   . GLU G 1 219 ? -29.523  19.704  29.236  1.00 75.63  ? 426 GLU G N   1 
ATOM   10428 C CA  . GLU G 1 219 ? -29.512  20.803  28.283  1.00 79.94  ? 426 GLU G CA  1 
ATOM   10429 C C   . GLU G 1 219 ? -28.082  21.227  27.977  1.00 73.28  ? 426 GLU G C   1 
ATOM   10430 O O   . GLU G 1 219 ? -27.288  21.458  28.894  1.00 68.45  ? 426 GLU G O   1 
ATOM   10431 C CB  . GLU G 1 219 ? -30.318  21.982  28.837  1.00 83.26  ? 426 GLU G CB  1 
ATOM   10432 N N   . PHE G 1 220 ? -27.763  21.340  26.685  1.00 70.35  ? 427 PHE G N   1 
ATOM   10433 C CA  . PHE G 1 220 ? -26.449  21.810  26.259  1.00 78.43  ? 427 PHE G CA  1 
ATOM   10434 C C   . PHE G 1 220 ? -26.551  22.806  25.107  1.00 76.73  ? 427 PHE G C   1 
ATOM   10435 O O   . PHE G 1 220 ? -27.392  22.636  24.211  1.00 71.34  ? 427 PHE G O   1 
ATOM   10436 C CB  . PHE G 1 220 ? -25.568  20.633  25.844  1.00 70.94  ? 427 PHE G CB  1 
ATOM   10437 C CG  . PHE G 1 220 ? -26.166  19.790  24.775  1.00 67.23  ? 427 PHE G CG  1 
ATOM   10438 C CD1 . PHE G 1 220 ? -27.040  18.763  25.100  1.00 67.93  ? 427 PHE G CD1 1 
ATOM   10439 C CD2 . PHE G 1 220 ? -25.856  20.026  23.440  1.00 64.13  ? 427 PHE G CD2 1 
ATOM   10440 C CE1 . PHE G 1 220 ? -27.598  17.975  24.109  1.00 70.29  ? 427 PHE G CE1 1 
ATOM   10441 C CE2 . PHE G 1 220 ? -26.403  19.255  22.439  1.00 71.13  ? 427 PHE G CE2 1 
ATOM   10442 C CZ  . PHE G 1 220 ? -27.278  18.219  22.770  1.00 79.27  ? 427 PHE G CZ  1 
ATOM   10443 N N   . PRO G 1 221 ? -25.691  23.849  25.094  1.00 81.38  ? 428 PRO G N   1 
ATOM   10444 C CA  . PRO G 1 221 ? -25.837  24.932  24.108  1.00 76.71  ? 428 PRO G CA  1 
ATOM   10445 C C   . PRO G 1 221 ? -24.904  24.823  22.914  1.00 79.24  ? 428 PRO G C   1 
ATOM   10446 O O   . PRO G 1 221 ? -23.901  24.096  22.945  1.00 75.76  ? 428 PRO G O   1 
ATOM   10447 C CB  . PRO G 1 221 ? -25.506  26.178  24.934  1.00 82.05  ? 428 PRO G CB  1 
ATOM   10448 C CG  . PRO G 1 221 ? -24.442  25.680  25.900  1.00 82.63  ? 428 PRO G CG  1 
ATOM   10449 C CD  . PRO G 1 221 ? -24.689  24.187  26.122  1.00 79.00  ? 428 PRO G CD  1 
ATOM   10450 N N   . GLU G 1 222 ? -25.233  25.569  21.853  1.00 82.14  ? 429 GLU G N   1 
ATOM   10451 C CA  . GLU G 1 222 ? -24.356  25.635  20.686  1.00 78.32  ? 429 GLU G CA  1 
ATOM   10452 C C   . GLU G 1 222 ? -23.076  26.393  21.003  1.00 72.04  ? 429 GLU G C   1 
ATOM   10453 O O   . GLU G 1 222 ? -22.008  26.055  20.475  1.00 68.89  ? 429 GLU G O   1 
ATOM   10454 C CB  . GLU G 1 222 ? -25.094  26.286  19.506  1.00 69.11  ? 429 GLU G CB  1 
ATOM   10455 C CG  . GLU G 1 222 ? -24.734  25.718  18.127  1.00 79.32  ? 429 GLU G CG  1 
ATOM   10456 C CD  . GLU G 1 222 ? -25.709  26.140  17.016  1.00 93.15  ? 429 GLU G CD  1 
ATOM   10457 O OE1 . GLU G 1 222 ? -26.687  26.872  17.317  1.00 86.96  ? 429 GLU G OE1 1 
ATOM   10458 O OE2 . GLU G 1 222 ? -25.486  25.738  15.842  1.00 88.64  ? 429 GLU G OE2 1 
ATOM   10459 N N   . GLN G 1 223 ? -23.182  27.380  21.890  1.00 75.98  ? 430 GLN G N   1 
ATOM   10460 C CA  . GLN G 1 223 ? -22.002  28.182  22.298  1.00 75.09  ? 430 GLN G CA  1 
ATOM   10461 C C   . GLN G 1 223 ? -21.689  27.895  23.762  1.00 73.34  ? 430 GLN G C   1 
ATOM   10462 O O   . GLN G 1 223 ? -22.521  28.241  24.612  1.00 71.37  ? 430 GLN G O   1 
ATOM   10463 C CB  . GLN G 1 223 ? -22.282  29.667  22.093  1.00 77.02  ? 430 GLN G CB  1 
ATOM   10464 N N   . LEU G 1 224 ? -20.528  27.300  24.034  1.00 75.15  ? 431 LEU G N   1 
ATOM   10465 C CA  . LEU G 1 224 ? -20.166  26.906  25.419  1.00 74.71  ? 431 LEU G CA  1 
ATOM   10466 C C   . LEU G 1 224 ? -19.110  27.857  25.981  1.00 76.80  ? 431 LEU G C   1 
ATOM   10467 O O   . LEU G 1 224 ? -17.962  27.824  25.505  1.00 69.20  ? 431 LEU G O   1 
ATOM   10468 C CB  . LEU G 1 224 ? -19.665  25.461  25.395  1.00 75.50  ? 431 LEU G CB  1 
ATOM   10469 C CG  . LEU G 1 224 ? -19.666  24.726  26.731  1.00 73.76  ? 431 LEU G CG  1 
ATOM   10470 C CD1 . LEU G 1 224 ? -20.742  25.254  27.659  1.00 68.75  ? 431 LEU G CD1 1 
ATOM   10471 C CD2 . LEU G 1 224 ? -19.811  23.229  26.533  1.00 74.03  ? 431 LEU G CD2 1 
ATOM   10472 N N   . PRO G 1 225 ? -19.465  28.713  26.960  1.00 77.02  ? 432 PRO G N   1 
ATOM   10473 C CA  . PRO G 1 225 ? -18.506  29.595  27.606  1.00 71.64  ? 432 PRO G CA  1 
ATOM   10474 C C   . PRO G 1 225 ? -17.832  28.871  28.775  1.00 71.64  ? 432 PRO G C   1 
ATOM   10475 O O   . PRO G 1 225 ? -18.463  28.690  29.792  1.00 70.49  ? 432 PRO G O   1 
ATOM   10476 C CB  . PRO G 1 225 ? -19.387  30.738  28.122  1.00 67.68  ? 432 PRO G CB  1 
ATOM   10477 C CG  . PRO G 1 225 ? -20.776  30.451  27.595  1.00 71.22  ? 432 PRO G CG  1 
ATOM   10478 C CD  . PRO G 1 225 ? -20.820  28.950  27.437  1.00 69.67  ? 432 PRO G CD  1 
ATOM   10479 N N   . LEU G 1 226 ? -16.558  28.522  28.620  1.00 72.38  ? 433 LEU G N   1 
ATOM   10480 C CA  . LEU G 1 226 ? -15.864  27.724  29.661  1.00 70.12  ? 433 LEU G CA  1 
ATOM   10481 C C   . LEU G 1 226 ? -14.738  28.508  30.340  1.00 73.15  ? 433 LEU G C   1 
ATOM   10482 O O   . LEU G 1 226 ? -13.911  27.869  31.002  1.00 75.48  ? 433 LEU G O   1 
ATOM   10483 C CB  . LEU G 1 226 ? -15.287  26.490  28.974  1.00 68.97  ? 433 LEU G CB  1 
ATOM   10484 C CG  . LEU G 1 226 ? -16.295  25.646  28.214  1.00 65.23  ? 433 LEU G CG  1 
ATOM   10485 C CD1 . LEU G 1 226 ? -15.606  24.824  27.144  1.00 67.12  ? 433 LEU G CD1 1 
ATOM   10486 C CD2 . LEU G 1 226 ? -17.030  24.757  29.187  1.00 69.36  ? 433 LEU G CD2 1 
ATOM   10487 N N   . ASP G 1 227 ? -14.710  29.829  30.203  1.00 69.41  ? 434 ASP G N   1 
ATOM   10488 C CA  . ASP G 1 227 ? -13.658  30.579  30.884  1.00 67.34  ? 434 ASP G CA  1 
ATOM   10489 C C   . ASP G 1 227 ? -13.793  30.464  32.398  1.00 70.32  ? 434 ASP G C   1 
ATOM   10490 O O   . ASP G 1 227 ? -12.777  30.421  33.108  1.00 71.59  ? 434 ASP G O   1 
ATOM   10491 C CB  . ASP G 1 227 ? -13.657  32.048  30.451  1.00 69.20  ? 434 ASP G CB  1 
ATOM   10492 C CG  . ASP G 1 227 ? -12.553  32.362  29.451  1.00 78.61  ? 434 ASP G CG  1 
ATOM   10493 O OD1 . ASP G 1 227 ? -11.547  31.621  29.407  1.00 79.34  ? 434 ASP G OD1 1 
ATOM   10494 O OD2 . ASP G 1 227 ? -12.689  33.350  28.697  1.00 84.16  ? 434 ASP G OD2 1 
ATOM   10495 N N   . GLU G 1 228 ? -15.027  30.375  32.907  1.00 65.51  ? 435 GLU G N   1 
ATOM   10496 C CA  . GLU G 1 228 ? -15.236  30.296  34.352  1.00 69.12  ? 435 GLU G CA  1 
ATOM   10497 C C   . GLU G 1 228 ? -14.489  29.120  34.979  1.00 67.47  ? 435 GLU G C   1 
ATOM   10498 O O   . GLU G 1 228 ? -14.133  29.170  36.164  1.00 63.24  ? 435 GLU G O   1 
ATOM   10499 C CB  . GLU G 1 228 ? -16.736  30.207  34.653  1.00 58.38  ? 435 GLU G CB  1 
ATOM   10500 C CG  . GLU G 1 228 ? -17.083  30.351  36.109  1.00 60.01  ? 435 GLU G CG  1 
ATOM   10501 C CD  . GLU G 1 228 ? -18.271  31.252  36.323  1.00 84.10  ? 435 GLU G CD  1 
ATOM   10502 O OE1 . GLU G 1 228 ? -18.137  32.463  36.036  1.00 95.80  ? 435 GLU G OE1 1 
ATOM   10503 O OE2 . GLU G 1 228 ? -19.335  30.759  36.773  1.00 77.14  ? 435 GLU G OE2 1 
ATOM   10504 N N   . PHE G 1 229 ? -14.197  28.088  34.195  1.00 64.42  ? 436 PHE G N   1 
ATOM   10505 C CA  . PHE G 1 229 ? -13.674  26.842  34.726  1.00 65.10  ? 436 PHE G CA  1 
ATOM   10506 C C   . PHE G 1 229 ? -12.173  26.672  34.506  1.00 66.45  ? 436 PHE G C   1 
ATOM   10507 O O   . PHE G 1 229 ? -11.610  25.652  34.917  1.00 62.37  ? 436 PHE G O   1 
ATOM   10508 C CB  . PHE G 1 229 ? -14.465  25.685  34.115  1.00 66.69  ? 436 PHE G CB  1 
ATOM   10509 C CG  . PHE G 1 229 ? -15.942  25.958  34.048  1.00 66.21  ? 436 PHE G CG  1 
ATOM   10510 C CD1 . PHE G 1 229 ? -16.686  26.085  35.213  1.00 63.56  ? 436 PHE G CD1 1 
ATOM   10511 C CD2 . PHE G 1 229 ? -16.572  26.147  32.831  1.00 60.11  ? 436 PHE G CD2 1 
ATOM   10512 C CE1 . PHE G 1 229 ? -18.029  26.367  35.160  1.00 61.61  ? 436 PHE G CE1 1 
ATOM   10513 C CE2 . PHE G 1 229 ? -17.906  26.419  32.776  1.00 57.46  ? 436 PHE G CE2 1 
ATOM   10514 C CZ  . PHE G 1 229 ? -18.637  26.536  33.940  1.00 59.82  ? 436 PHE G CZ  1 
ATOM   10515 N N   . LEU G 1 230 ? -11.516  27.642  33.874  1.00 66.61  ? 437 LEU G N   1 
ATOM   10516 C CA  . LEU G 1 230 ? -10.069  27.728  33.926  1.00 54.90  ? 437 LEU G CA  1 
ATOM   10517 C C   . LEU G 1 230 ? -9.633   28.250  35.289  1.00 62.15  ? 437 LEU G C   1 
ATOM   10518 O O   . LEU G 1 230 ? -10.428  28.814  36.050  1.00 63.06  ? 437 LEU G O   1 
ATOM   10519 C CB  . LEU G 1 230 ? -9.553   28.650  32.838  1.00 52.77  ? 437 LEU G CB  1 
ATOM   10520 C CG  . LEU G 1 230 ? -9.861   28.113  31.459  1.00 59.83  ? 437 LEU G CG  1 
ATOM   10521 C CD1 . LEU G 1 230 ? -9.634   29.177  30.396  1.00 63.96  ? 437 LEU G CD1 1 
ATOM   10522 C CD2 . LEU G 1 230 ? -9.006   26.880  31.201  1.00 59.24  ? 437 LEU G CD2 1 
ATOM   10523 N N   . GLN G 1 231 ? -8.356   28.037  35.612  1.00 62.85  ? 438 GLN G N   1 
ATOM   10524 C CA  . GLN G 1 231 ? -7.807   28.665  36.809  1.00 59.52  ? 438 GLN G CA  1 
ATOM   10525 C C   . GLN G 1 231 ? -7.266   30.040  36.478  1.00 55.40  ? 438 GLN G C   1 
ATOM   10526 O O   . GLN G 1 231 ? -7.358   30.963  37.294  1.00 53.87  ? 438 GLN G O   1 
ATOM   10527 C CB  . GLN G 1 231 ? -6.706   27.797  37.435  1.00 51.15  ? 438 GLN G CB  1 
ATOM   10528 C CG  . GLN G 1 231 ? -6.238   28.259  38.804  1.00 46.44  ? 438 GLN G CG  1 
ATOM   10529 C CD  . GLN G 1 231 ? -7.206   27.894  39.913  1.00 52.78  ? 438 GLN G CD  1 
ATOM   10530 O OE1 . GLN G 1 231 ? -8.415   27.768  39.689  1.00 55.02  ? 438 GLN G OE1 1 
ATOM   10531 N NE2 . GLN G 1 231 ? -6.681   27.729  41.125  1.00 43.30  ? 438 GLN G NE2 1 
ATOM   10532 N N   . LYS G 1 232 ? -6.714   30.171  35.281  1.00 53.66  ? 439 LYS G N   1 
ATOM   10533 C CA  . LYS G 1 232 ? -6.343   31.448  34.704  1.00 58.72  ? 439 LYS G CA  1 
ATOM   10534 C C   . LYS G 1 232 ? -6.827   31.456  33.265  1.00 63.61  ? 439 LYS G C   1 
ATOM   10535 O O   . LYS G 1 232 ? -6.709   30.452  32.552  1.00 59.09  ? 439 LYS G O   1 
ATOM   10536 C CB  . LYS G 1 232 ? -4.830   31.684  34.759  1.00 59.72  ? 439 LYS G CB  1 
ATOM   10537 C CG  . LYS G 1 232 ? -4.390   33.080  34.322  1.00 63.06  ? 439 LYS G CG  1 
ATOM   10538 C CD  . LYS G 1 232 ? -2.879   33.217  34.448  1.00 66.69  ? 439 LYS G CD  1 
ATOM   10539 C CE  . LYS G 1 232 ? -2.290   34.322  33.577  1.00 71.32  ? 439 LYS G CE  1 
ATOM   10540 N NZ  . LYS G 1 232 ? -1.963   35.563  34.329  1.00 69.69  ? 439 LYS G NZ  1 
ATOM   10541 N N   . THR G 1 233 ? -7.390   32.575  32.844  1.00 67.39  ? 440 THR G N   1 
ATOM   10542 C CA  . THR G 1 233 ? -7.778   32.689  31.449  1.00 75.90  ? 440 THR G CA  1 
ATOM   10543 C C   . THR G 1 233 ? -6.643   33.320  30.642  1.00 74.42  ? 440 THR G C   1 
ATOM   10544 O O   . THR G 1 233 ? -5.509   33.460  31.108  1.00 77.87  ? 440 THR G O   1 
ATOM   10545 C CB  . THR G 1 233 ? -9.078   33.474  31.317  1.00 71.59  ? 440 THR G CB  1 
ATOM   10546 O OG1 . THR G 1 233 ? -8.818   34.855  31.583  1.00 78.90  ? 440 THR G OG1 1 
ATOM   10547 C CG2 . THR G 1 233 ? -10.132  32.934  32.292  1.00 66.63  ? 440 THR G CG2 1 
ATOM   10548 N N   . ASP G 1 234 ? -6.947   33.683  29.408  1.00 73.59  ? 441 ASP G N   1 
ATOM   10549 C CA  . ASP G 1 234 ? -6.035   34.307  28.463  1.00 74.51  ? 441 ASP G CA  1 
ATOM   10550 C C   . ASP G 1 234 ? -6.860   35.201  27.549  1.00 81.71  ? 441 ASP G C   1 
ATOM   10551 O O   . ASP G 1 234 ? -7.653   34.700  26.741  1.00 81.75  ? 441 ASP G O   1 
ATOM   10552 C CB  . ASP G 1 234 ? -5.272   33.255  27.652  1.00 68.07  ? 441 ASP G CB  1 
ATOM   10553 C CG  . ASP G 1 234 ? -4.321   33.865  26.635  1.00 73.54  ? 441 ASP G CG  1 
ATOM   10554 O OD1 . ASP G 1 234 ? -4.287   35.103  26.488  1.00 77.72  ? 441 ASP G OD1 1 
ATOM   10555 O OD2 . ASP G 1 234 ? -3.586   33.100  25.979  1.00 76.99  ? 441 ASP G OD2 1 
ATOM   10556 N N   . PRO G 1 235 ? -6.715   36.524  27.654  1.00 84.20  ? 442 PRO G N   1 
ATOM   10557 C CA  . PRO G 1 235 ? -7.429   37.409  26.715  1.00 82.42  ? 442 PRO G CA  1 
ATOM   10558 C C   . PRO G 1 235 ? -7.084   37.145  25.253  1.00 81.55  ? 442 PRO G C   1 
ATOM   10559 O O   . PRO G 1 235 ? -7.976   37.167  24.396  1.00 79.95  ? 442 PRO G O   1 
ATOM   10560 C CB  . PRO G 1 235 ? -7.001   38.806  27.177  1.00 81.86  ? 442 PRO G CB  1 
ATOM   10561 C CG  . PRO G 1 235 ? -6.634   38.617  28.638  1.00 76.41  ? 442 PRO G CG  1 
ATOM   10562 C CD  . PRO G 1 235 ? -6.004   37.269  28.706  1.00 77.55  ? 442 PRO G CD  1 
ATOM   10563 N N   . LYS G 1 236 ? -5.818   36.853  24.944  1.00 82.82  ? 443 LYS G N   1 
ATOM   10564 C CA  . LYS G 1 236 ? -5.409   36.554  23.573  1.00 82.79  ? 443 LYS G CA  1 
ATOM   10565 C C   . LYS G 1 236 ? -6.034   35.269  23.028  1.00 84.86  ? 443 LYS G C   1 
ATOM   10566 O O   . LYS G 1 236 ? -5.735   34.909  21.881  1.00 81.86  ? 443 LYS G O   1 
ATOM   10567 C CB  . LYS G 1 236 ? -3.876   36.466  23.487  1.00 77.82  ? 443 LYS G CB  1 
ATOM   10568 N N   . ASP G 1 237 ? -6.882   34.574  23.813  1.00 84.77  ? 444 ASP G N   1 
ATOM   10569 C CA  . ASP G 1 237 ? -7.575   33.345  23.425  1.00 79.04  ? 444 ASP G CA  1 
ATOM   10570 C C   . ASP G 1 237 ? -8.615   32.959  24.469  1.00 78.10  ? 444 ASP G C   1 
ATOM   10571 O O   . ASP G 1 237 ? -8.276   32.303  25.461  1.00 82.16  ? 444 ASP G O   1 
ATOM   10572 C CB  . ASP G 1 237 ? -6.596   32.184  23.246  1.00 71.33  ? 444 ASP G CB  1 
ATOM   10573 C CG  . ASP G 1 237 ? -7.306   30.844  23.088  1.00 76.06  ? 444 ASP G CG  1 
ATOM   10574 O OD1 . ASP G 1 237 ? -8.447   30.813  22.569  1.00 77.40  ? 444 ASP G OD1 1 
ATOM   10575 O OD2 . ASP G 1 237 ? -6.737   29.813  23.503  1.00 82.91  ? 444 ASP G OD2 1 
ATOM   10576 N N   . PRO G 1 238 ? -9.884   33.307  24.279  1.00 77.50  ? 445 PRO G N   1 
ATOM   10577 C CA  . PRO G 1 238 ? -10.903  32.906  25.253  1.00 77.36  ? 445 PRO G CA  1 
ATOM   10578 C C   . PRO G 1 238 ? -11.270  31.437  25.102  1.00 79.55  ? 445 PRO G C   1 
ATOM   10579 O O   . PRO G 1 238 ? -10.978  30.788  24.092  1.00 71.65  ? 445 PRO G O   1 
ATOM   10580 C CB  . PRO G 1 238 ? -12.099  33.808  24.925  1.00 80.87  ? 445 PRO G CB  1 
ATOM   10581 C CG  . PRO G 1 238 ? -11.592  34.815  23.912  1.00 79.31  ? 445 PRO G CG  1 
ATOM   10582 C CD  . PRO G 1 238 ? -10.443  34.159  23.221  1.00 81.35  ? 445 PRO G CD  1 
ATOM   10583 N N   . ALA G 1 239 ? -11.941  30.923  26.139  1.00 81.55  ? 446 ALA G N   1 
ATOM   10584 C CA  . ALA G 1 239 ? -12.390  29.529  26.181  1.00 75.09  ? 446 ALA G CA  1 
ATOM   10585 C C   . ALA G 1 239 ? -13.846  29.442  25.712  1.00 72.32  ? 446 ALA G C   1 
ATOM   10586 O O   . ALA G 1 239 ? -14.770  29.077  26.446  1.00 69.39  ? 446 ALA G O   1 
ATOM   10587 C CB  . ALA G 1 239 ? -12.217  28.958  27.582  1.00 72.62  ? 446 ALA G CB  1 
ATOM   10588 N N   . ASN G 1 240 ? -14.034  29.779  24.445  1.00 66.96  ? 447 ASN G N   1 
ATOM   10589 C CA  . ASN G 1 240 ? -15.338  29.733  23.808  1.00 70.05  ? 447 ASN G CA  1 
ATOM   10590 C C   . ASN G 1 240 ? -15.371  28.520  22.898  1.00 67.30  ? 447 ASN G C   1 
ATOM   10591 O O   . ASN G 1 240 ? -14.486  28.346  22.052  1.00 64.16  ? 447 ASN G O   1 
ATOM   10592 C CB  . ASN G 1 240 ? -15.609  31.014  23.026  1.00 77.12  ? 447 ASN G CB  1 
ATOM   10593 C CG  . ASN G 1 240 ? -15.928  32.187  23.933  1.00 80.87  ? 447 ASN G CG  1 
ATOM   10594 O OD1 . ASN G 1 240 ? -16.493  32.022  25.020  1.00 76.95  ? 447 ASN G OD1 1 
ATOM   10595 N ND2 . ASN G 1 240 ? -15.550  33.379  23.500  1.00 81.40  ? 447 ASN G ND2 1 
ATOM   10596 N N   . TYR G 1 241 ? -16.377  27.672  23.084  1.00 71.18  ? 448 TYR G N   1 
ATOM   10597 C CA  . TYR G 1 241 ? -16.472  26.414  22.362  1.00 71.44  ? 448 TYR G CA  1 
ATOM   10598 C C   . TYR G 1 241 ? -17.749  26.384  21.536  1.00 66.95  ? 448 TYR G C   1 
ATOM   10599 O O   . TYR G 1 241 ? -18.835  26.700  22.038  1.00 63.59  ? 448 TYR G O   1 
ATOM   10600 C CB  . TYR G 1 241 ? -16.420  25.229  23.332  1.00 72.47  ? 448 TYR G CB  1 
ATOM   10601 N N   . ILE G 1 242 ? -17.605  26.004  20.274  1.00 68.18  ? 449 ILE G N   1 
ATOM   10602 C CA  . ILE G 1 242 ? -18.713  25.880  19.334  1.00 78.90  ? 449 ILE G CA  1 
ATOM   10603 C C   . ILE G 1 242 ? -19.052  24.400  19.175  1.00 76.68  ? 449 ILE G C   1 
ATOM   10604 O O   . ILE G 1 242 ? -18.157  23.564  18.992  1.00 71.12  ? 449 ILE G O   1 
ATOM   10605 C CB  . ILE G 1 242 ? -18.353  26.522  17.979  1.00 74.81  ? 449 ILE G CB  1 
ATOM   10606 C CG1 . ILE G 1 242 ? -18.155  28.030  18.144  1.00 78.77  ? 449 ILE G CG1 1 
ATOM   10607 C CG2 . ILE G 1 242 ? -19.400  26.224  16.933  1.00 71.14  ? 449 ILE G CG2 1 
ATOM   10608 C CD1 . ILE G 1 242 ? -18.329  28.834  16.855  1.00 87.09  ? 449 ILE G CD1 1 
ATOM   10609 N N   . LEU G 1 243 ? -20.344  24.066  19.249  1.00 74.47  ? 450 LEU G N   1 
ATOM   10610 C CA  . LEU G 1 243 ? -20.785  22.655  19.120  1.00 67.02  ? 450 LEU G CA  1 
ATOM   10611 C C   . LEU G 1 243 ? -20.416  22.125  17.746  1.00 69.09  ? 450 LEU G C   1 
ATOM   10612 O O   . LEU G 1 243 ? -20.818  22.735  16.750  1.00 73.69  ? 450 LEU G O   1 
ATOM   10613 C CB  . LEU G 1 243 ? -22.298  22.568  19.307  1.00 72.84  ? 450 LEU G CB  1 
ATOM   10614 C CG  . LEU G 1 243 ? -22.809  21.497  20.267  1.00 72.36  ? 450 LEU G CG  1 
ATOM   10615 C CD1 . LEU G 1 243 ? -24.324  21.487  20.292  1.00 74.93  ? 450 LEU G CD1 1 
ATOM   10616 C CD2 . LEU G 1 243 ? -22.275  20.121  19.915  1.00 64.70  ? 450 LEU G CD2 1 
ATOM   10617 N N   . HIS G 1 244 ? -19.701  21.010  17.717  1.00 70.72  ? 451 HIS G N   1 
ATOM   10618 C CA  . HIS G 1 244 ? -19.348  20.367  16.460  1.00 62.40  ? 451 HIS G CA  1 
ATOM   10619 C C   . HIS G 1 244 ? -20.049  19.041  16.247  1.00 70.66  ? 451 HIS G C   1 
ATOM   10620 O O   . HIS G 1 244 ? -20.341  18.705  15.098  1.00 77.60  ? 451 HIS G O   1 
ATOM   10621 C CB  . HIS G 1 244 ? -17.832  20.141  16.374  1.00 61.99  ? 451 HIS G CB  1 
ATOM   10622 C CG  . HIS G 1 244 ? -17.354  19.618  15.050  1.00 63.22  ? 451 HIS G CG  1 
ATOM   10623 N ND1 . HIS G 1 244 ? -16.831  18.352  14.894  1.00 64.59  ? 451 HIS G ND1 1 
ATOM   10624 C CD2 . HIS G 1 244 ? -17.281  20.202  13.829  1.00 66.75  ? 451 HIS G CD2 1 
ATOM   10625 C CE1 . HIS G 1 244 ? -16.482  18.169  13.630  1.00 66.34  ? 451 HIS G CE1 1 
ATOM   10626 N NE2 . HIS G 1 244 ? -16.743  19.277  12.963  1.00 63.31  ? 451 HIS G NE2 1 
ATOM   10627 N N   . ALA G 1 245 ? -20.302  18.300  17.326  1.00 67.44  ? 452 ALA G N   1 
ATOM   10628 C CA  . ALA G 1 245 ? -20.876  16.951  17.140  1.00 68.69  ? 452 ALA G CA  1 
ATOM   10629 C C   . ALA G 1 245 ? -21.677  16.486  18.345  1.00 69.69  ? 452 ALA G C   1 
ATOM   10630 O O   . ALA G 1 245 ? -21.276  16.769  19.473  1.00 73.72  ? 452 ALA G O   1 
ATOM   10631 C CB  . ALA G 1 245 ? -19.781  15.967  16.850  1.00 65.33  ? 452 ALA G CB  1 
ATOM   10632 N N   . VAL G 1 246 ? -22.780  15.796  18.089  1.00 71.92  ? 453 VAL G N   1 
ATOM   10633 C CA  . VAL G 1 246 ? -23.580  15.205  19.161  1.00 77.54  ? 453 VAL G CA  1 
ATOM   10634 C C   . VAL G 1 246 ? -23.708  13.715  18.877  1.00 77.11  ? 453 VAL G C   1 
ATOM   10635 O O   . VAL G 1 246 ? -24.239  13.318  17.831  1.00 76.56  ? 453 VAL G O   1 
ATOM   10636 C CB  . VAL G 1 246 ? -24.969  15.860  19.289  1.00 74.40  ? 453 VAL G CB  1 
ATOM   10637 C CG1 . VAL G 1 246 ? -25.891  14.998  20.163  1.00 74.16  ? 453 VAL G CG1 1 
ATOM   10638 C CG2 . VAL G 1 246 ? -24.853  17.246  19.885  1.00 70.96  ? 453 VAL G CG2 1 
ATOM   10639 N N   . LEU G 1 247 ? -23.180  12.907  19.795  1.00 70.56  ? 454 LEU G N   1 
ATOM   10640 C CA  . LEU G 1 247 ? -23.317  11.438  19.683  1.00 71.90  ? 454 LEU G CA  1 
ATOM   10641 C C   . LEU G 1 247 ? -24.572  11.082  20.474  1.00 70.08  ? 454 LEU G C   1 
ATOM   10642 O O   . LEU G 1 247 ? -24.629  11.420  21.657  1.00 63.52  ? 454 LEU G O   1 
ATOM   10643 C CB  . LEU G 1 247 ? -22.072  10.746  20.246  1.00 68.52  ? 454 LEU G CB  1 
ATOM   10644 C CG  . LEU G 1 247 ? -20.835  10.621  19.356  1.00 66.42  ? 454 LEU G CG  1 
ATOM   10645 C CD1 . LEU G 1 247 ? -21.156  9.892   18.075  1.00 70.01  ? 454 LEU G CD1 1 
ATOM   10646 C CD2 . LEU G 1 247 ? -20.167  11.957  19.074  1.00 68.19  ? 454 LEU G CD2 1 
ATOM   10647 N N   . VAL G 1 248 ? -25.533  10.430  19.836  1.00 68.31  ? 455 VAL G N   1 
ATOM   10648 C CA  . VAL G 1 248 ? -26.822  10.122  20.433  1.00 73.17  ? 455 VAL G CA  1 
ATOM   10649 C C   . VAL G 1 248 ? -26.898  8.624   20.670  1.00 69.09  ? 455 VAL G C   1 
ATOM   10650 O O   . VAL G 1 248 ? -26.375  7.819   19.887  1.00 69.62  ? 455 VAL G O   1 
ATOM   10651 C CB  . VAL G 1 248 ? -27.995  10.612  19.559  1.00 75.16  ? 455 VAL G CB  1 
ATOM   10652 N N   . HIS G 1 249 ? -27.538  8.256   21.765  1.00 66.28  ? 456 HIS G N   1 
ATOM   10653 C CA  . HIS G 1 249 ? -27.706  6.862   22.119  1.00 70.86  ? 456 HIS G CA  1 
ATOM   10654 C C   . HIS G 1 249 ? -29.182  6.601   22.364  1.00 75.42  ? 456 HIS G C   1 
ATOM   10655 O O   . HIS G 1 249 ? -29.825  7.324   23.131  1.00 77.90  ? 456 HIS G O   1 
ATOM   10656 C CB  . HIS G 1 249 ? -26.884  6.513   23.358  1.00 72.04  ? 456 HIS G CB  1 
ATOM   10657 C CG  . HIS G 1 249 ? -27.161  5.147   23.890  1.00 64.86  ? 456 HIS G CG  1 
ATOM   10658 N ND1 . HIS G 1 249 ? -27.966  4.927   24.987  1.00 63.76  ? 456 HIS G ND1 1 
ATOM   10659 C CD2 . HIS G 1 249 ? -26.747  3.929   23.470  1.00 66.44  ? 456 HIS G CD2 1 
ATOM   10660 C CE1 . HIS G 1 249 ? -28.033  3.629   25.221  1.00 71.72  ? 456 HIS G CE1 1 
ATOM   10661 N NE2 . HIS G 1 249 ? -27.308  3.001   24.311  1.00 71.11  ? 456 HIS G NE2 1 
ATOM   10662 N N   . SER G 1 250 ? -29.728  5.589   21.691  1.00 74.09  ? 457 SER G N   1 
ATOM   10663 C CA  . SER G 1 250 ? -31.163  5.250   21.835  1.00 73.76  ? 457 SER G CA  1 
ATOM   10664 C C   . SER G 1 250 ? -31.305  3.847   22.418  1.00 72.96  ? 457 SER G C   1 
ATOM   10665 O O   . SER G 1 250 ? -31.149  2.896   21.663  1.00 76.16  ? 457 SER G O   1 
ATOM   10666 C CB  . SER G 1 250 ? -31.855  5.331   20.512  1.00 75.24  ? 457 SER G CB  1 
ATOM   10667 O OG  . SER G 1 250 ? -33.262  5.266   20.675  1.00 88.79  ? 457 SER G OG  1 
ATOM   10668 N N   . GLY G 1 251 ? -31.642  3.743   23.702  1.00 72.89  ? 458 GLY G N   1 
ATOM   10669 C CA  . GLY G 1 251 ? -31.803  2.414   24.323  1.00 75.62  ? 458 GLY G CA  1 
ATOM   10670 C C   . GLY G 1 251 ? -31.474  2.351   25.802  1.00 77.31  ? 458 GLY G C   1 
ATOM   10671 O O   . GLY G 1 251 ? -31.895  3.249   26.536  1.00 76.45  ? 458 GLY G O   1 
ATOM   10672 N N   . ASP G 1 252 ? -30.762  1.303   26.223  1.00 87.06  ? 459 ASP G N   1 
ATOM   10673 C CA  . ASP G 1 252 ? -30.414  1.102   27.656  1.00 89.61  ? 459 ASP G CA  1 
ATOM   10674 C C   . ASP G 1 252 ? -28.936  0.745   27.808  1.00 91.85  ? 459 ASP G C   1 
ATOM   10675 O O   . ASP G 1 252 ? -28.218  0.716   26.798  1.00 101.50 ? 459 ASP G O   1 
ATOM   10676 C CB  . ASP G 1 252 ? -31.272  0.007   28.294  1.00 91.58  ? 459 ASP G CB  1 
ATOM   10677 N N   . ASN G 1 253 ? -28.517  0.446   29.033  1.00 87.14  ? 460 ASN G N   1 
ATOM   10678 C CA  . ASN G 1 253 ? -27.091  0.150   29.313  1.00 94.15  ? 460 ASN G CA  1 
ATOM   10679 C C   . ASN G 1 253 ? -26.620  -1.035  28.475  1.00 97.59  ? 460 ASN G C   1 
ATOM   10680 O O   . ASN G 1 253 ? -25.522  -0.951  27.906  1.00 86.67  ? 460 ASN G O   1 
ATOM   10681 C CB  . ASN G 1 253 ? -26.909  -0.139  30.803  1.00 97.11  ? 460 ASN G CB  1 
ATOM   10682 C CG  . ASN G 1 253 ? -26.159  0.943   31.545  1.00 91.19  ? 460 ASN G CG  1 
ATOM   10683 O OD1 . ASN G 1 253 ? -26.669  2.042   31.730  1.00 95.10  ? 460 ASN G OD1 1 
ATOM   10684 N ND2 . ASN G 1 253 ? -24.950  0.636   31.986  1.00 80.16  ? 460 ASN G ND2 1 
ATOM   10685 N N   . HIS G 1 254 ? -27.426  -2.090  28.398  1.00 112.62 ? 461 HIS G N   1 
ATOM   10686 C CA  . HIS G 1 254 ? -27.007  -3.344  27.716  1.00 124.99 ? 461 HIS G CA  1 
ATOM   10687 C C   . HIS G 1 254 ? -27.205  -3.264  26.204  1.00 129.03 ? 461 HIS G C   1 
ATOM   10688 O O   . HIS G 1 254 ? -26.496  -4.001  25.494  1.00 147.20 ? 461 HIS G O   1 
ATOM   10689 C CB  . HIS G 1 254 ? -27.774  -4.534  28.300  1.00 133.24 ? 461 HIS G CB  1 
ATOM   10690 C CG  . HIS G 1 254 ? -27.934  -4.483  29.779  1.00 131.71 ? 461 HIS G CG  1 
ATOM   10691 N ND1 . HIS G 1 254 ? -29.172  -4.410  30.381  1.00 136.61 ? 461 HIS G ND1 1 
ATOM   10692 C CD2 . HIS G 1 254 ? -27.024  -4.492  30.775  1.00 131.37 ? 461 HIS G CD2 1 
ATOM   10693 C CE1 . HIS G 1 254 ? -29.019  -4.375  31.688  1.00 136.51 ? 461 HIS G CE1 1 
ATOM   10694 N NE2 . HIS G 1 254 ? -27.710  -4.424  31.955  1.00 138.95 ? 461 HIS G NE2 1 
ATOM   10695 N N   . GLY G 1 255 ? -28.125  -2.425  25.725  1.00 105.27 ? 462 GLY G N   1 
ATOM   10696 C CA  . GLY G 1 255 ? -28.388  -2.435  24.275  1.00 97.78  ? 462 GLY G CA  1 
ATOM   10697 C C   . GLY G 1 255 ? -29.056  -1.187  23.756  1.00 85.20  ? 462 GLY G C   1 
ATOM   10698 O O   . GLY G 1 255 ? -29.837  -0.581  24.492  1.00 78.70  ? 462 GLY G O   1 
ATOM   10699 N N   . GLY G 1 256 ? -28.768  -0.851  22.500  1.00 76.79  ? 463 GLY G N   1 
ATOM   10700 C CA  . GLY G 1 256 ? -29.348  0.362   21.917  1.00 69.54  ? 463 GLY G CA  1 
ATOM   10701 C C   . GLY G 1 256 ? -28.908  0.676   20.504  1.00 71.48  ? 463 GLY G C   1 
ATOM   10702 O O   . GLY G 1 256 ? -28.560  -0.263  19.775  1.00 72.79  ? 463 GLY G O   1 
ATOM   10703 N N   . HIS G 1 257 ? -28.956  1.958   20.124  1.00 69.03  ? 464 HIS G N   1 
ATOM   10704 C CA  . HIS G 1 257 ? -28.523  2.352   18.795  1.00 71.15  ? 464 HIS G CA  1 
ATOM   10705 C C   . HIS G 1 257 ? -27.646  3.586   18.903  1.00 67.77  ? 464 HIS G C   1 
ATOM   10706 O O   . HIS G 1 257 ? -27.799  4.376   19.838  1.00 68.01  ? 464 HIS G O   1 
ATOM   10707 C CB  . HIS G 1 257 ? -29.703  2.644   17.866  1.00 67.91  ? 464 HIS G CB  1 
ATOM   10708 C CG  . HIS G 1 257 ? -29.298  2.832   16.441  1.00 66.73  ? 464 HIS G CG  1 
ATOM   10709 N ND1 . HIS G 1 257 ? -28.587  1.880   15.737  1.00 65.49  ? 464 HIS G ND1 1 
ATOM   10710 C CD2 . HIS G 1 257 ? -29.476  3.869   15.596  1.00 65.54  ? 464 HIS G CD2 1 
ATOM   10711 C CE1 . HIS G 1 257 ? -28.354  2.320   14.516  1.00 65.52  ? 464 HIS G CE1 1 
ATOM   10712 N NE2 . HIS G 1 257 ? -28.880  3.527   14.406  1.00 75.29  ? 464 HIS G NE2 1 
ATOM   10713 N N   . TYR G 1 258 ? -26.734  3.737   17.945  1.00 66.60  ? 465 TYR G N   1 
ATOM   10714 C CA  . TYR G 1 258 ? -25.826  4.906   17.943  1.00 71.85  ? 465 TYR G CA  1 
ATOM   10715 C C   . TYR G 1 258 ? -25.919  5.669   16.622  1.00 73.14  ? 465 TYR G C   1 
ATOM   10716 O O   . TYR G 1 258 ? -25.835  5.042   15.556  1.00 74.46  ? 465 TYR G O   1 
ATOM   10717 C CB  . TYR G 1 258 ? -24.390  4.478   18.228  1.00 68.91  ? 465 TYR G CB  1 
ATOM   10718 C CG  . TYR G 1 258 ? -23.968  4.569   19.667  1.00 68.38  ? 465 TYR G CG  1 
ATOM   10719 C CD1 . TYR G 1 258 ? -23.932  5.785   20.321  1.00 64.72  ? 465 TYR G CD1 1 
ATOM   10720 C CD2 . TYR G 1 258 ? -23.591  3.437   20.365  1.00 68.20  ? 465 TYR G CD2 1 
ATOM   10721 C CE1 . TYR G 1 258 ? -23.546  5.877   21.645  1.00 62.50  ? 465 TYR G CE1 1 
ATOM   10722 C CE2 . TYR G 1 258 ? -23.194  3.511   21.686  1.00 69.42  ? 465 TYR G CE2 1 
ATOM   10723 C CZ  . TYR G 1 258 ? -23.173  4.735   22.325  1.00 66.66  ? 465 TYR G CZ  1 
ATOM   10724 O OH  . TYR G 1 258 ? -22.777  4.814   23.622  1.00 68.79  ? 465 TYR G OH  1 
ATOM   10725 N N   . VAL G 1 259 ? -26.073  6.985   16.707  1.00 77.93  ? 466 VAL G N   1 
ATOM   10726 C CA  . VAL G 1 259 ? -26.162  7.900   15.536  1.00 73.16  ? 466 VAL G CA  1 
ATOM   10727 C C   . VAL G 1 259 ? -25.357  9.148   15.888  1.00 70.42  ? 466 VAL G C   1 
ATOM   10728 O O   . VAL G 1 259 ? -25.109  9.386   17.084  1.00 74.86  ? 466 VAL G O   1 
ATOM   10729 C CB  . VAL G 1 259 ? -27.616  8.289   15.224  1.00 72.38  ? 466 VAL G CB  1 
ATOM   10730 C CG1 . VAL G 1 259 ? -28.353  7.204   14.469  1.00 71.23  ? 466 VAL G CG1 1 
ATOM   10731 C CG2 . VAL G 1 259 ? -28.392  8.681   16.469  1.00 73.87  ? 466 VAL G CG2 1 
ATOM   10732 N N   . VAL G 1 260 ? -24.967  9.917   14.876  1.00 73.81  ? 467 VAL G N   1 
ATOM   10733 C CA  . VAL G 1 260 ? -24.161  11.147  15.125  1.00 77.96  ? 467 VAL G CA  1 
ATOM   10734 C C   . VAL G 1 260 ? -24.734  12.332  14.346  1.00 77.43  ? 467 VAL G C   1 
ATOM   10735 O O   . VAL G 1 260 ? -24.947  12.214  13.128  1.00 72.03  ? 467 VAL G O   1 
ATOM   10736 C CB  . VAL G 1 260 ? -22.659  10.941  14.844  1.00 74.42  ? 467 VAL G CB  1 
ATOM   10737 C CG1 . VAL G 1 260 ? -22.360  10.496  13.422  1.00 67.32  ? 467 VAL G CG1 1 
ATOM   10738 C CG2 . VAL G 1 260 ? -21.842  12.164  15.223  1.00 74.01  ? 467 VAL G CG2 1 
ATOM   10739 N N   . TYR G 1 261 ? -25.040  13.412  15.059  1.00 78.68  ? 468 TYR G N   1 
ATOM   10740 C CA  . TYR G 1 261 ? -25.479  14.659  14.396  1.00 82.20  ? 468 TYR G CA  1 
ATOM   10741 C C   . TYR G 1 261 ? -24.228  15.524  14.267  1.00 80.66  ? 468 TYR G C   1 
ATOM   10742 O O   . TYR G 1 261 ? -23.486  15.624  15.254  1.00 83.60  ? 468 TYR G O   1 
ATOM   10743 C CB  . TYR G 1 261 ? -26.592  15.308  15.215  1.00 79.36  ? 468 TYR G CB  1 
ATOM   10744 N N   . LEU G 1 262 ? -24.013  16.132  13.105  1.00 80.01  ? 469 LEU G N   1 
ATOM   10745 C CA  . LEU G 1 262 ? -22.747  16.871  12.898  1.00 80.11  ? 469 LEU G CA  1 
ATOM   10746 C C   . LEU G 1 262 ? -22.918  18.075  11.968  1.00 84.75  ? 469 LEU G C   1 
ATOM   10747 O O   . LEU G 1 262 ? -23.587  17.920  10.940  1.00 80.95  ? 469 LEU G O   1 
ATOM   10748 C CB  . LEU G 1 262 ? -21.747  15.880  12.298  1.00 72.71  ? 469 LEU G CB  1 
ATOM   10749 C CG  . LEU G 1 262 ? -20.446  15.681  13.066  1.00 72.84  ? 469 LEU G CG  1 
ATOM   10750 C CD1 . LEU G 1 262 ? -19.936  14.265  12.880  1.00 72.90  ? 469 LEU G CD1 1 
ATOM   10751 C CD2 . LEU G 1 262 ? -19.407  16.671  12.590  1.00 72.03  ? 469 LEU G CD2 1 
ATOM   10752 N N   . ASN G 1 263 ? -22.380  19.237  12.346  1.00 85.45  ? 470 ASN G N   1 
ATOM   10753 C CA  . ASN G 1 263 ? -22.313  20.423  11.453  1.00 80.48  ? 470 ASN G CA  1 
ATOM   10754 C C   . ASN G 1 263 ? -20.829  20.452  11.084  1.00 78.22  ? 470 ASN G C   1 
ATOM   10755 O O   . ASN G 1 263 ? -20.082  21.244  11.675  1.00 77.40  ? 470 ASN G O   1 
ATOM   10756 C CB  . ASN G 1 263 ? -22.870  21.702  12.090  1.00 81.74  ? 470 ASN G CB  1 
ATOM   10757 C CG  . ASN G 1 263 ? -22.288  22.085  13.434  1.00 79.62  ? 470 ASN G CG  1 
ATOM   10758 O OD1 . ASN G 1 263 ? -21.834  21.237  14.192  1.00 81.90  ? 470 ASN G OD1 1 
ATOM   10759 N ND2 . ASN G 1 263 ? -22.302  23.371  13.738  1.00 76.18  ? 470 ASN G ND2 1 
ATOM   10760 N N   . PRO G 1 264 ? -20.354  19.632  10.123  1.00 73.62  ? 471 PRO G N   1 
ATOM   10761 C CA  . PRO G 1 264 ? -18.912  19.469  9.874   1.00 67.22  ? 471 PRO G CA  1 
ATOM   10762 C C   . PRO G 1 264 ? -18.062  20.710  9.591   1.00 68.21  ? 471 PRO G C   1 
ATOM   10763 O O   . PRO G 1 264 ? -16.863  20.603  9.695   1.00 73.42  ? 471 PRO G O   1 
ATOM   10764 C CB  . PRO G 1 264 ? -18.914  18.600  8.618   1.00 69.08  ? 471 PRO G CB  1 
ATOM   10765 C CG  . PRO G 1 264 ? -20.189  17.826  8.727   1.00 75.68  ? 471 PRO G CG  1 
ATOM   10766 C CD  . PRO G 1 264 ? -21.160  18.898  9.151   1.00 75.49  ? 471 PRO G CD  1 
ATOM   10767 N N   . LYS G 1 265 ? -18.692  21.824  9.235   1.00 79.59  ? 472 LYS G N   1 
ATOM   10768 C CA  . LYS G 1 265 ? -17.943  23.058  8.884   1.00 85.90  ? 472 LYS G CA  1 
ATOM   10769 C C   . LYS G 1 265 ? -18.155  24.121  9.965   1.00 84.91  ? 472 LYS G C   1 
ATOM   10770 O O   . LYS G 1 265 ? -17.627  25.229  9.791   1.00 85.38  ? 472 LYS G O   1 
ATOM   10771 C CB  . LYS G 1 265 ? -18.393  23.567  7.512   1.00 73.98  ? 472 LYS G CB  1 
ATOM   10772 N N   . GLY G 1 266 ? -18.891  23.798  11.031  1.00 77.42  ? 473 GLY G N   1 
ATOM   10773 C CA  . GLY G 1 266 ? -19.164  24.802  12.041  1.00 76.31  ? 473 GLY G CA  1 
ATOM   10774 C C   . GLY G 1 266 ? -20.058  25.926  11.572  1.00 88.03  ? 473 GLY G C   1 
ATOM   10775 O O   . GLY G 1 266 ? -20.088  26.993  12.199  1.00 84.69  ? 473 GLY G O   1 
ATOM   10776 N N   . ASP G 1 267 ? -20.791  25.712  10.477  1.00 88.82  ? 474 ASP G N   1 
ATOM   10777 C CA  . ASP G 1 267 ? -21.647  26.722  9.880   1.00 77.29  ? 474 ASP G CA  1 
ATOM   10778 C C   . ASP G 1 267 ? -23.090  26.605  10.326  1.00 82.44  ? 474 ASP G C   1 
ATOM   10779 O O   . ASP G 1 267 ? -23.960  27.223  9.715   1.00 92.52  ? 474 ASP G O   1 
ATOM   10780 C CB  . ASP G 1 267 ? -21.577  26.635  8.357   1.00 81.33  ? 474 ASP G CB  1 
ATOM   10781 C CG  . ASP G 1 267 ? -21.761  25.217  7.841   1.00 89.78  ? 474 ASP G CG  1 
ATOM   10782 O OD1 . ASP G 1 267 ? -22.164  24.335  8.633   1.00 84.50  ? 474 ASP G OD1 1 
ATOM   10783 O OD2 . ASP G 1 267 ? -21.489  24.988  6.636   1.00 93.70  ? 474 ASP G OD2 1 
ATOM   10784 N N   . GLY G 1 268 ? -23.369  25.833  11.372  1.00 83.17  ? 475 GLY G N   1 
ATOM   10785 C CA  . GLY G 1 268 ? -24.740  25.580  11.756  1.00 84.09  ? 475 GLY G CA  1 
ATOM   10786 C C   . GLY G 1 268 ? -25.553  24.799  10.750  1.00 79.12  ? 475 GLY G C   1 
ATOM   10787 O O   . GLY G 1 268 ? -26.772  24.724  10.902  1.00 77.14  ? 475 GLY G O   1 
ATOM   10788 N N   . LYS G 1 269 ? -24.921  24.222  9.722   1.00 83.18  ? 476 LYS G N   1 
ATOM   10789 C CA  . LYS G 1 269 ? -25.620  23.470  8.676   1.00 83.84  ? 476 LYS G CA  1 
ATOM   10790 C C   . LYS G 1 269 ? -25.505  21.977  8.978   1.00 80.14  ? 476 LYS G C   1 
ATOM   10791 O O   . LYS G 1 269 ? -24.661  21.264  8.433   1.00 72.71  ? 476 LYS G O   1 
ATOM   10792 C CB  . LYS G 1 269 ? -25.051  23.815  7.296   1.00 80.55  ? 476 LYS G CB  1 
ATOM   10793 N N   . TRP G 1 270 ? -26.391  21.532  9.872   1.00 87.15  ? 477 TRP G N   1 
ATOM   10794 C CA  . TRP G 1 270 ? -26.304  20.157  10.420  1.00 83.73  ? 477 TRP G CA  1 
ATOM   10795 C C   . TRP G 1 270 ? -26.886  19.058  9.541   1.00 82.66  ? 477 TRP G C   1 
ATOM   10796 O O   . TRP G 1 270 ? -27.797  19.340  8.751   1.00 81.23  ? 477 TRP G O   1 
ATOM   10797 C CB  . TRP G 1 270 ? -27.023  20.103  11.776  1.00 80.12  ? 477 TRP G CB  1 
ATOM   10798 C CG  . TRP G 1 270 ? -26.479  20.920  12.907  1.00 87.50  ? 477 TRP G CG  1 
ATOM   10799 C CD1 . TRP G 1 270 ? -26.676  22.250  13.130  1.00 95.01  ? 477 TRP G CD1 1 
ATOM   10800 C CD2 . TRP G 1 270 ? -25.727  20.437  14.034  1.00 89.83  ? 477 TRP G CD2 1 
ATOM   10801 N NE1 . TRP G 1 270 ? -26.063  22.636  14.291  1.00 95.29  ? 477 TRP G NE1 1 
ATOM   10802 C CE2 . TRP G 1 270 ? -25.477  21.544  14.870  1.00 90.11  ? 477 TRP G CE2 1 
ATOM   10803 C CE3 . TRP G 1 270 ? -25.224  19.188  14.408  1.00 83.86  ? 477 TRP G CE3 1 
ATOM   10804 C CZ2 . TRP G 1 270 ? -24.742  21.435  16.049  1.00 81.70  ? 477 TRP G CZ2 1 
ATOM   10805 C CZ3 . TRP G 1 270 ? -24.500  19.080  15.574  1.00 81.98  ? 477 TRP G CZ3 1 
ATOM   10806 C CH2 . TRP G 1 270 ? -24.264  20.189  16.382  1.00 85.38  ? 477 TRP G CH2 1 
ATOM   10807 N N   . CYS G 1 271 ? -26.370  17.846  9.713   1.00 87.28  ? 478 CYS G N   1 
ATOM   10808 C CA  . CYS G 1 271 ? -26.878  16.621  9.059   1.00 90.06  ? 478 CYS G CA  1 
ATOM   10809 C C   . CYS G 1 271 ? -26.794  15.472  10.077  1.00 85.95  ? 478 CYS G C   1 
ATOM   10810 O O   . CYS G 1 271 ? -26.003  15.588  11.023  1.00 80.21  ? 478 CYS G O   1 
ATOM   10811 C CB  . CYS G 1 271 ? -26.030  16.262  7.844   1.00 87.70  ? 478 CYS G CB  1 
ATOM   10812 S SG  . CYS G 1 271 ? -25.939  17.539  6.565   1.00 84.42  ? 478 CYS G SG  1 
ATOM   10813 N N   . LYS G 1 272 ? -27.590  14.415  9.917   1.00 88.21  ? 479 LYS G N   1 
ATOM   10814 C CA  . LYS G 1 272 ? -27.558  13.225  10.757  1.00 85.22  ? 479 LYS G CA  1 
ATOM   10815 C C   . LYS G 1 272 ? -26.917  12.099  9.960   1.00 82.12  ? 479 LYS G C   1 
ATOM   10816 O O   . LYS G 1 272 ? -26.907  12.126  8.728   1.00 81.52  ? 479 LYS G O   1 
ATOM   10817 C CB  . LYS G 1 272 ? -28.965  12.816  11.228  1.00 79.97  ? 479 LYS G CB  1 
ATOM   10818 C CG  . LYS G 1 272 ? -29.245  13.118  12.698  1.00 82.57  ? 479 LYS G CG  1 
ATOM   10819 N N   . PHE G 1 273 ? -26.369  11.113  10.667  1.00 81.21  ? 480 PHE G N   1 
ATOM   10820 C CA  . PHE G 1 273 ? -25.708  9.968   10.035  1.00 85.47  ? 480 PHE G CA  1 
ATOM   10821 C C   . PHE G 1 273 ? -26.154  8.672   10.729  1.00 85.36  ? 480 PHE G C   1 
ATOM   10822 O O   . PHE G 1 273 ? -25.559  8.257   11.730  1.00 83.95  ? 480 PHE G O   1 
ATOM   10823 C CB  . PHE G 1 273 ? -24.184  10.160  10.069  1.00 72.51  ? 480 PHE G CB  1 
ATOM   10824 N N   . ASP G 1 274 ? -27.229  8.056   10.216  1.00 79.38  ? 481 ASP G N   1 
ATOM   10825 C CA  . ASP G 1 274 ? -27.738  6.771   10.763  1.00 79.04  ? 481 ASP G CA  1 
ATOM   10826 C C   . ASP G 1 274 ? -27.064  5.647   9.997   1.00 83.04  ? 481 ASP G C   1 
ATOM   10827 O O   . ASP G 1 274 ? -27.744  5.009   9.182   1.00 89.45  ? 481 ASP G O   1 
ATOM   10828 C CB  . ASP G 1 274 ? -29.256  6.659   10.640  1.00 83.97  ? 481 ASP G CB  1 
ATOM   10829 C CG  . ASP G 1 274 ? -29.905  5.678   11.601  1.00 88.55  ? 481 ASP G CG  1 
ATOM   10830 O OD1 . ASP G 1 274 ? -29.546  4.488   11.562  1.00 92.12  ? 481 ASP G OD1 1 
ATOM   10831 O OD2 . ASP G 1 274 ? -30.787  6.110   12.365  1.00 80.30  ? 481 ASP G OD2 1 
ATOM   10832 N N   . ASP G 1 275 ? -25.772  5.453   10.234  1.00 85.43  ? 482 ASP G N   1 
ATOM   10833 C CA  . ASP G 1 275 ? -24.988  4.401   9.537   1.00 82.37  ? 482 ASP G CA  1 
ATOM   10834 C C   . ASP G 1 275 ? -25.041  4.651   8.030   1.00 82.21  ? 482 ASP G C   1 
ATOM   10835 O O   . ASP G 1 275 ? -24.254  5.475   7.561   1.00 88.21  ? 482 ASP G O   1 
ATOM   10836 C CB  . ASP G 1 275 ? -25.423  2.992   9.957   1.00 79.98  ? 482 ASP G CB  1 
ATOM   10837 C CG  . ASP G 1 275 ? -25.374  2.731   11.453  1.00 81.83  ? 482 ASP G CG  1 
ATOM   10838 O OD1 . ASP G 1 275 ? -24.644  3.453   12.155  1.00 78.41  ? 482 ASP G OD1 1 
ATOM   10839 O OD2 . ASP G 1 275 ? -26.068  1.802   11.901  1.00 81.22  ? 482 ASP G OD2 1 
ATOM   10840 N N   . ASP G 1 276 ? -25.941  3.984   7.317   1.00 86.89  ? 483 ASP G N   1 
ATOM   10841 C CA  . ASP G 1 276 ? -25.996  4.077   5.835   1.00 87.05  ? 483 ASP G CA  1 
ATOM   10842 C C   . ASP G 1 276 ? -26.758  5.313   5.357   1.00 90.43  ? 483 ASP G C   1 
ATOM   10843 O O   . ASP G 1 276 ? -26.660  5.615   4.160   1.00 94.58  ? 483 ASP G O   1 
ATOM   10844 C CB  . ASP G 1 276 ? -26.681  2.834   5.271   1.00 80.51  ? 483 ASP G CB  1 
ATOM   10845 C CG  . ASP G 1 276 ? -27.912  2.420   6.054   1.00 80.89  ? 483 ASP G CG  1 
ATOM   10846 O OD1 . ASP G 1 276 ? -27.757  1.665   7.029   1.00 80.71  ? 483 ASP G OD1 1 
ATOM   10847 O OD2 . ASP G 1 276 ? -29.014  2.863   5.685   1.00 90.42  ? 483 ASP G OD2 1 
ATOM   10848 N N   . VAL G 1 277 ? -27.469  6.009   6.242   1.00 89.40  ? 484 VAL G N   1 
ATOM   10849 C CA  . VAL G 1 277 ? -28.344  7.129   5.790   1.00 89.14  ? 484 VAL G CA  1 
ATOM   10850 C C   . VAL G 1 277 ? -27.869  8.457   6.369   1.00 87.37  ? 484 VAL G C   1 
ATOM   10851 O O   . VAL G 1 277 ? -27.978  8.636   7.587   1.00 83.67  ? 484 VAL G O   1 
ATOM   10852 C CB  . VAL G 1 277 ? -29.814  6.868   6.164   1.00 80.84  ? 484 VAL G CB  1 
ATOM   10853 N N   . VAL G 1 278 ? -27.406  9.362   5.507   1.00 89.27  ? 485 VAL G N   1 
ATOM   10854 C CA  . VAL G 1 278 ? -27.004  10.701  5.951   1.00 82.94  ? 485 VAL G CA  1 
ATOM   10855 C C   . VAL G 1 278 ? -28.095  11.687  5.544   1.00 86.83  ? 485 VAL G C   1 
ATOM   10856 O O   . VAL G 1 278 ? -28.582  11.644  4.408   1.00 88.19  ? 485 VAL G O   1 
ATOM   10857 C CB  . VAL G 1 278 ? -25.633  11.088  5.354   1.00 76.00  ? 485 VAL G CB  1 
ATOM   10858 N N   . SER G 1 279 ? -28.533  12.495  6.509   1.00 93.78  ? 486 SER G N   1 
ATOM   10859 C CA  . SER G 1 279 ? -29.712  13.352  6.248   1.00 86.97  ? 486 SER G CA  1 
ATOM   10860 C C   . SER G 1 279 ? -29.586  14.737  6.859   1.00 90.42  ? 486 SER G C   1 
ATOM   10861 O O   . SER G 1 279 ? -29.520  14.814  8.089   1.00 92.84  ? 486 SER G O   1 
ATOM   10862 C CB  . SER G 1 279 ? -30.942  12.663  6.786   1.00 83.19  ? 486 SER G CB  1 
ATOM   10863 O OG  . SER G 1 279 ? -31.912  13.586  7.262   1.00 81.77  ? 486 SER G OG  1 
ATOM   10864 N N   . ARG G 1 280 ? -29.595  15.780  6.035   1.00 84.01  ? 487 ARG G N   1 
ATOM   10865 C CA  . ARG G 1 280 ? -29.665  17.162  6.493   1.00 85.93  ? 487 ARG G CA  1 
ATOM   10866 C C   . ARG G 1 280 ? -30.797  17.326  7.523   1.00 86.57  ? 487 ARG G C   1 
ATOM   10867 O O   . ARG G 1 280 ? -31.754  16.548  7.561   1.00 89.06  ? 487 ARG G O   1 
ATOM   10868 C CB  . ARG G 1 280 ? -29.872  18.101  5.297   1.00 79.74  ? 487 ARG G CB  1 
ATOM   10869 N N   . CYS G 1 281 ? -30.686  18.351  8.374   1.00 81.12  ? 488 CYS G N   1 
ATOM   10870 C CA  . CYS G 1 281 ? -31.606  18.453  9.508   1.00 82.53  ? 488 CYS G CA  1 
ATOM   10871 C C   . CYS G 1 281 ? -31.561  19.861  10.076  1.00 84.06  ? 488 CYS G C   1 
ATOM   10872 O O   . CYS G 1 281 ? -30.659  20.646  9.773   1.00 88.30  ? 488 CYS G O   1 
ATOM   10873 C CB  . CYS G 1 281 ? -31.282  17.418  10.598  1.00 88.30  ? 488 CYS G CB  1 
ATOM   10874 S SG  . CYS G 1 281 ? -29.673  17.630  11.486  1.00 89.74  ? 488 CYS G SG  1 
ATOM   10875 N N   . THR G 1 282 ? -32.472  20.115  11.018  1.00 86.99  ? 489 THR G N   1 
ATOM   10876 C CA  . THR G 1 282 ? -32.524  21.436  11.691  1.00 86.36  ? 489 THR G CA  1 
ATOM   10877 C C   . THR G 1 282 ? -31.575  21.466  12.889  1.00 90.29  ? 489 THR G C   1 
ATOM   10878 O O   . THR G 1 282 ? -31.159  20.391  13.352  1.00 88.54  ? 489 THR G O   1 
ATOM   10879 C CB  . THR G 1 282 ? -33.951  21.781  12.136  1.00 89.39  ? 489 THR G CB  1 
ATOM   10880 O OG1 . THR G 1 282 ? -34.246  21.139  13.376  1.00 92.42  ? 489 THR G OG1 1 
ATOM   10881 C CG2 . THR G 1 282 ? -34.997  21.397  11.112  1.00 87.90  ? 489 THR G CG2 1 
ATOM   10882 N N   . LYS G 1 283 ? -31.270  22.666  13.378  1.00 91.24  ? 490 LYS G N   1 
ATOM   10883 C CA  . LYS G 1 283 ? -30.357  22.821  14.538  1.00 91.51  ? 490 LYS G CA  1 
ATOM   10884 C C   . LYS G 1 283 ? -31.111  22.503  15.826  1.00 90.91  ? 490 LYS G C   1 
ATOM   10885 O O   . LYS G 1 283 ? -30.529  22.669  16.893  1.00 89.07  ? 490 LYS G O   1 
ATOM   10886 C CB  . LYS G 1 283 ? -29.799  24.245  14.572  1.00 89.18  ? 490 LYS G CB  1 
ATOM   10887 N N   . GLU G 1 284 ? -32.375  22.111  15.723  1.00 92.55  ? 491 GLU G N   1 
ATOM   10888 C CA  . GLU G 1 284 ? -33.116  21.673  16.928  1.00 91.16  ? 491 GLU G CA  1 
ATOM   10889 C C   . GLU G 1 284 ? -33.195  20.153  16.863  1.00 84.58  ? 491 GLU G C   1 
ATOM   10890 O O   . GLU G 1 284 ? -33.138  19.533  17.916  1.00 83.72  ? 491 GLU G O   1 
ATOM   10891 C CB  . GLU G 1 284 ? -34.496  22.322  16.971  1.00 91.90  ? 491 GLU G CB  1 
ATOM   10892 N N   . GLU G 1 285 ? -33.275  19.595  15.656  1.00 84.36  ? 492 GLU G N   1 
ATOM   10893 C CA  . GLU G 1 285 ? -33.295  18.122  15.470  1.00 90.45  ? 492 GLU G CA  1 
ATOM   10894 C C   . GLU G 1 285 ? -31.948  17.525  15.882  1.00 92.64  ? 492 GLU G C   1 
ATOM   10895 O O   . GLU G 1 285 ? -31.877  16.293  16.017  1.00 89.64  ? 492 GLU G O   1 
ATOM   10896 C CB  . GLU G 1 285 ? -33.616  17.786  14.016  1.00 86.97  ? 492 GLU G CB  1 
ATOM   10897 C CG  . GLU G 1 285 ? -35.099  17.795  13.704  1.00 88.49  ? 492 GLU G CG  1 
ATOM   10898 C CD  . GLU G 1 285 ? -35.431  17.523  12.248  1.00 96.33  ? 492 GLU G CD  1 
ATOM   10899 O OE1 . GLU G 1 285 ? -34.663  17.963  11.375  1.00 94.48  ? 492 GLU G OE1 1 
ATOM   10900 O OE2 . GLU G 1 285 ? -36.458  16.871  11.990  1.00 97.39  ? 492 GLU G OE2 1 
ATOM   10901 N N   . ALA G 1 286 ? -30.924  18.360  16.074  1.00 91.36  ? 493 ALA G N   1 
ATOM   10902 C CA  . ALA G 1 286 ? -29.624  17.876  16.508  1.00 88.13  ? 493 ALA G CA  1 
ATOM   10903 C C   . ALA G 1 286 ? -29.270  18.300  17.920  1.00 82.15  ? 493 ALA G C   1 
ATOM   10904 O O   . ALA G 1 286 ? -28.376  17.699  18.519  1.00 81.56  ? 493 ALA G O   1 
ATOM   10905 C CB  . ALA G 1 286 ? -28.519  18.362  15.558  1.00 86.59  ? 493 ALA G CB  1 
ATOM   10906 N N   . ILE G 1 287 ? -29.944  19.304  18.471  1.00 79.53  ? 494 ILE G N   1 
ATOM   10907 C CA  . ILE G 1 287 ? -29.571  19.790  19.790  1.00 76.11  ? 494 ILE G CA  1 
ATOM   10908 C C   . ILE G 1 287 ? -30.742  19.650  20.746  1.00 79.86  ? 494 ILE G C   1 
ATOM   10909 O O   . ILE G 1 287 ? -30.738  18.778  21.622  1.00 80.59  ? 494 ILE G O   1 
ATOM   10910 C CB  . ILE G 1 287 ? -29.086  21.244  19.723  1.00 70.68  ? 494 ILE G CB  1 
ATOM   10911 C CG1 . ILE G 1 287 ? -27.902  21.353  18.757  1.00 71.17  ? 494 ILE G CG1 1 
ATOM   10912 C CG2 . ILE G 1 287 ? -28.737  21.729  21.125  1.00 71.32  ? 494 ILE G CG2 1 
ATOM   10913 C CD1 . ILE G 1 287 ? -27.659  22.727  18.210  1.00 73.21  ? 494 ILE G CD1 1 
ATOM   10914 N N   . GLU G 1 288 ? -31.752  20.513  20.584  1.00 85.15  ? 495 GLU G N   1 
ATOM   10915 C CA  . GLU G 1 288 ? -32.872  20.538  21.520  1.00 77.92  ? 495 GLU G CA  1 
ATOM   10916 C C   . GLU G 1 288 ? -33.626  19.217  21.531  1.00 76.30  ? 495 GLU G C   1 
ATOM   10917 O O   . GLU G 1 288 ? -34.200  18.847  22.561  1.00 71.82  ? 495 GLU G O   1 
ATOM   10918 C CB  . GLU G 1 288 ? -33.814  21.696  21.181  1.00 80.00  ? 495 GLU G CB  1 
ATOM   10919 N N   . HIS G 1 289 ? -33.617  18.484  20.413  1.00 81.11  ? 496 HIS G N   1 
ATOM   10920 C CA  . HIS G 1 289 ? -34.283  17.186  20.310  1.00 81.90  ? 496 HIS G CA  1 
ATOM   10921 C C   . HIS G 1 289 ? -33.440  16.030  20.843  1.00 83.34  ? 496 HIS G C   1 
ATOM   10922 O O   . HIS G 1 289 ? -33.855  14.870  20.713  1.00 83.78  ? 496 HIS G O   1 
ATOM   10923 C CB  . HIS G 1 289 ? -34.677  16.897  18.856  1.00 80.25  ? 496 HIS G CB  1 
ATOM   10924 N N   . ASN G 1 290 ? -32.271  16.311  21.421  1.00 87.55  ? 497 ASN G N   1 
ATOM   10925 C CA  . ASN G 1 290 ? -31.456  15.293  22.072  1.00 84.18  ? 497 ASN G CA  1 
ATOM   10926 C C   . ASN G 1 290 ? -31.214  15.595  23.544  1.00 78.28  ? 497 ASN G C   1 
ATOM   10927 O O   . ASN G 1 290 ? -30.452  14.871  24.198  1.00 81.47  ? 497 ASN G O   1 
ATOM   10928 C CB  . ASN G 1 290 ? -30.115  15.125  21.342  1.00 73.69  ? 497 ASN G CB  1 
ATOM   10929 C CG  . ASN G 1 290 ? -30.281  14.557  19.945  1.00 79.38  ? 497 ASN G CG  1 
ATOM   10930 O OD1 . ASN G 1 290 ? -29.829  15.143  18.965  1.00 80.97  ? 497 ASN G OD1 1 
ATOM   10931 N ND2 . ASN G 1 290 ? -30.936  13.411  19.848  1.00 83.46  ? 497 ASN G ND2 1 
ATOM   10932 N N   . TYR G 1 291 ? -31.840  16.633  24.082  1.00 69.99  ? 498 TYR G N   1 
ATOM   10933 C CA  . TYR G 1 291 ? -31.732  16.941  25.501  1.00 75.67  ? 498 TYR G CA  1 
ATOM   10934 C C   . TYR G 1 291 ? -32.444  15.863  26.316  1.00 71.34  ? 498 TYR G C   1 
ATOM   10935 O O   . TYR G 1 291 ? -32.242  15.749  27.523  1.00 69.58  ? 498 TYR G O   1 
ATOM   10936 C CB  . TYR G 1 291 ? -32.312  18.335  25.800  1.00 73.02  ? 498 TYR G CB  1 
ATOM   10937 N N   . VAL G 1 300 ? -39.568  5.305   21.243  1.00 120.48 ? 507 VAL G N   1 
ATOM   10938 C CA  . VAL G 1 300 ? -38.265  5.181   21.958  1.00 113.35 ? 507 VAL G CA  1 
ATOM   10939 C C   . VAL G 1 300 ? -37.699  6.574   22.212  1.00 109.21 ? 507 VAL G C   1 
ATOM   10940 O O   . VAL G 1 300 ? -36.596  6.641   22.756  1.00 103.83 ? 507 VAL G O   1 
ATOM   10941 C CB  . VAL G 1 300 ? -37.255  4.320   21.180  1.00 114.69 ? 507 VAL G CB  1 
ATOM   10942 C CG1 . VAL G 1 300 ? -37.628  2.848   21.213  1.00 119.17 ? 507 VAL G CG1 1 
ATOM   10943 C CG2 . VAL G 1 300 ? -37.073  4.802   19.749  1.00 102.62 ? 507 VAL G CG2 1 
ATOM   10944 N N   . ARG G 1 301 ? -38.408  7.637   21.819  1.00 112.41 ? 508 ARG G N   1 
ATOM   10945 C CA  . ARG G 1 301 ? -37.917  8.980   22.169  1.00 108.75 ? 508 ARG G CA  1 
ATOM   10946 C C   . ARG G 1 301 ? -37.786  9.128   23.673  1.00 103.61 ? 508 ARG G C   1 
ATOM   10947 O O   . ARG G 1 301 ? -37.089  10.028  24.137  1.00 106.68 ? 508 ARG G O   1 
ATOM   10948 C CB  . ARG G 1 301 ? -38.846  10.090  21.633  1.00 107.15 ? 508 ARG G CB  1 
ATOM   10949 N N   . HIS G 1 302 ? -38.400  8.219   24.434  1.00 102.68 ? 509 HIS G N   1 
ATOM   10950 C CA  . HIS G 1 302 ? -38.144  8.152   25.868  1.00 97.65  ? 509 HIS G CA  1 
ATOM   10951 C C   . HIS G 1 302 ? -36.687  7.761   26.180  1.00 99.83  ? 509 HIS G C   1 
ATOM   10952 O O   . HIS G 1 302 ? -36.103  8.264   27.140  1.00 97.16  ? 509 HIS G O   1 
ATOM   10953 C CB  . HIS G 1 302 ? -39.098  7.165   26.528  1.00 90.84  ? 509 HIS G CB  1 
ATOM   10954 N N   . CYS G 1 303 ? -36.080  6.853   25.412  1.00 104.43 ? 510 CYS G N   1 
ATOM   10955 C CA  . CYS G 1 303 ? -34.721  6.434   25.722  1.00 93.67  ? 510 CYS G CA  1 
ATOM   10956 C C   . CYS G 1 303 ? -33.711  6.904   24.676  1.00 87.53  ? 510 CYS G C   1 
ATOM   10957 O O   . CYS G 1 303 ? -32.688  6.257   24.488  1.00 82.57  ? 510 CYS G O   1 
ATOM   10958 C CB  . CYS G 1 303 ? -34.658  4.934   25.900  1.00 79.28  ? 510 CYS G CB  1 
ATOM   10959 S SG  . CYS G 1 303 ? -35.143  3.906   24.425  1.00 99.01  ? 510 CYS G SG  1 
ATOM   10960 N N   . THR G 1 304 ? -34.050  7.926   23.899  1.00 87.29  ? 511 THR G N   1 
ATOM   10961 C CA  . THR G 1 304 ? -33.133  8.568   22.955  1.00 84.22  ? 511 THR G CA  1 
ATOM   10962 C C   . THR G 1 304 ? -32.648  9.872   23.560  1.00 84.12  ? 511 THR G C   1 
ATOM   10963 O O   . THR G 1 304 ? -33.439  10.608  24.159  1.00 94.27  ? 511 THR G O   1 
ATOM   10964 C CB  . THR G 1 304 ? -33.824  8.856   21.625  1.00 86.71  ? 511 THR G CB  1 
ATOM   10965 O OG1 . THR G 1 304 ? -34.705  7.776   21.340  1.00 95.11  ? 511 THR G OG1 1 
ATOM   10966 C CG2 . THR G 1 304 ? -32.805  8.991   20.478  1.00 70.87  ? 511 THR G CG2 1 
ATOM   10967 N N   . ASN G 1 305 ? -31.331  10.071  23.490  1.00 81.74  ? 512 ASN G N   1 
ATOM   10968 C CA  . ASN G 1 305 ? -30.707  11.296  24.041  1.00 76.38  ? 512 ASN G CA  1 
ATOM   10969 C C   . ASN G 1 305 ? -29.225  11.345  23.686  1.00 76.89  ? 512 ASN G C   1 
ATOM   10970 O O   . ASN G 1 305 ? -28.687  10.333  23.230  1.00 67.47  ? 512 ASN G O   1 
ATOM   10971 C CB  . ASN G 1 305 ? -30.831  11.412  25.561  1.00 71.65  ? 512 ASN G CB  1 
ATOM   10972 C CG  . ASN G 1 305 ? -30.683  10.099  26.291  1.00 79.61  ? 512 ASN G CG  1 
ATOM   10973 O OD1 . ASN G 1 305 ? -29.593  9.543   26.367  1.00 84.55  ? 512 ASN G OD1 1 
ATOM   10974 N ND2 . ASN G 1 305 ? -31.781  9.606   26.833  1.00 78.18  ? 512 ASN G ND2 1 
ATOM   10975 N N   . ALA G 1 306 ? -28.593  12.485  23.927  1.00 80.28  ? 513 ALA G N   1 
ATOM   10976 C CA  . ALA G 1 306 ? -27.175  12.694  23.680  1.00 75.27  ? 513 ALA G CA  1 
ATOM   10977 C C   . ALA G 1 306 ? -26.320  12.033  24.755  1.00 69.93  ? 513 ALA G C   1 
ATOM   10978 O O   . ALA G 1 306 ? -26.641  12.086  25.949  1.00 66.19  ? 513 ALA G O   1 
ATOM   10979 C CB  . ALA G 1 306 ? -26.873  14.193  23.625  1.00 72.69  ? 513 ALA G CB  1 
ATOM   10980 N N   . TYR G 1 307 ? -25.180  11.462  24.332  1.00 69.38  ? 514 TYR G N   1 
ATOM   10981 C CA  . TYR G 1 307 ? -24.222  10.792  25.257  1.00 67.18  ? 514 TYR G CA  1 
ATOM   10982 C C   . TYR G 1 307 ? -22.842  11.453  25.153  1.00 70.65  ? 514 TYR G C   1 
ATOM   10983 O O   . TYR G 1 307 ? -22.295  11.844  26.176  1.00 65.56  ? 514 TYR G O   1 
ATOM   10984 C CB  . TYR G 1 307 ? -24.117  9.308   24.909  1.00 65.44  ? 514 TYR G CB  1 
ATOM   10985 C CG  . TYR G 1 307 ? -23.168  8.488   25.745  1.00 63.31  ? 514 TYR G CG  1 
ATOM   10986 C CD1 . TYR G 1 307 ? -23.186  8.547   27.127  1.00 61.45  ? 514 TYR G CD1 1 
ATOM   10987 C CD2 . TYR G 1 307 ? -22.261  7.632   25.148  1.00 55.56  ? 514 TYR G CD2 1 
ATOM   10988 C CE1 . TYR G 1 307 ? -22.322  7.783   27.892  1.00 58.26  ? 514 TYR G CE1 1 
ATOM   10989 C CE2 . TYR G 1 307 ? -21.390  6.861   25.896  1.00 56.80  ? 514 TYR G CE2 1 
ATOM   10990 C CZ  . TYR G 1 307 ? -21.422  6.936   27.275  1.00 58.63  ? 514 TYR G CZ  1 
ATOM   10991 O OH  . TYR G 1 307 ? -20.571  6.181   28.022  1.00 66.39  ? 514 TYR G OH  1 
ATOM   10992 N N   . MET G 1 308 ? -22.320  11.594  23.942  1.00 69.51  ? 515 MET G N   1 
ATOM   10993 C CA  . MET G 1 308 ? -20.988  12.215  23.783  1.00 68.98  ? 515 MET G CA  1 
ATOM   10994 C C   . MET G 1 308 ? -21.085  13.484  22.941  1.00 71.29  ? 515 MET G C   1 
ATOM   10995 O O   . MET G 1 308 ? -21.554  13.414  21.824  1.00 69.53  ? 515 MET G O   1 
ATOM   10996 C CB  . MET G 1 308 ? -19.985  11.243  23.158  1.00 69.37  ? 515 MET G CB  1 
ATOM   10997 C CG  . MET G 1 308 ? -18.660  11.186  23.877  1.00 70.91  ? 515 MET G CG  1 
ATOM   10998 S SD  . MET G 1 308 ? -17.453  10.239  22.930  1.00 69.25  ? 515 MET G SD  1 
ATOM   10999 C CE  . MET G 1 308 ? -16.977  11.453  21.702  1.00 63.83  ? 515 MET G CE  1 
ATOM   11000 N N   . LEU G 1 309 ? -20.656  14.604  23.512  1.00 69.91  ? 516 LEU G N   1 
ATOM   11001 C CA  . LEU G 1 309 ? -20.671  15.889  22.782  1.00 62.65  ? 516 LEU G CA  1 
ATOM   11002 C C   . LEU G 1 309 ? -19.240  16.222  22.377  1.00 62.64  ? 516 LEU G C   1 
ATOM   11003 O O   . LEU G 1 309 ? -18.336  15.986  23.172  1.00 69.56  ? 516 LEU G O   1 
ATOM   11004 C CB  . LEU G 1 309 ? -21.251  16.970  23.693  1.00 56.73  ? 516 LEU G CB  1 
ATOM   11005 C CG  . LEU G 1 309 ? -22.576  16.633  24.366  1.00 64.02  ? 516 LEU G CG  1 
ATOM   11006 C CD1 . LEU G 1 309 ? -22.956  17.717  25.352  1.00 62.16  ? 516 LEU G CD1 1 
ATOM   11007 C CD2 . LEU G 1 309 ? -23.674  16.455  23.336  1.00 62.19  ? 516 LEU G CD2 1 
ATOM   11008 N N   . VAL G 1 310 ? -19.055  16.726  21.166  1.00 63.55  ? 517 VAL G N   1 
ATOM   11009 C CA  . VAL G 1 310 ? -17.706  17.118  20.677  1.00 62.57  ? 517 VAL G CA  1 
ATOM   11010 C C   . VAL G 1 310 ? -17.788  18.608  20.351  1.00 67.39  ? 517 VAL G C   1 
ATOM   11011 O O   . VAL G 1 310 ? -18.479  18.959  19.398  1.00 66.70  ? 517 VAL G O   1 
ATOM   11012 C CB  . VAL G 1 310 ? -17.234  16.282  19.476  1.00 59.60  ? 517 VAL G CB  1 
ATOM   11013 C CG1 . VAL G 1 310 ? -15.960  16.833  18.858  1.00 60.95  ? 517 VAL G CG1 1 
ATOM   11014 C CG2 . VAL G 1 310 ? -17.060  14.821  19.844  1.00 61.33  ? 517 VAL G CG2 1 
ATOM   11015 N N   . TYR G 1 311 ? -17.197  19.446  21.193  1.00 64.95  ? 518 TYR G N   1 
ATOM   11016 C CA  . TYR G 1 311 ? -17.143  20.904  20.967  1.00 61.20  ? 518 TYR G CA  1 
ATOM   11017 C C   . TYR G 1 311 ? -15.755  21.264  20.450  1.00 68.71  ? 518 TYR G C   1 
ATOM   11018 O O   . TYR G 1 311 ? -14.833  20.444  20.572  1.00 74.07  ? 518 TYR G O   1 
ATOM   11019 C CB  . TYR G 1 311 ? -17.406  21.648  22.269  1.00 59.46  ? 518 TYR G CB  1 
ATOM   11020 C CG  . TYR G 1 311 ? -18.845  21.724  22.702  1.00 70.25  ? 518 TYR G CG  1 
ATOM   11021 C CD1 . TYR G 1 311 ? -19.484  20.623  23.239  1.00 67.11  ? 518 TYR G CD1 1 
ATOM   11022 C CD2 . TYR G 1 311 ? -19.558  22.905  22.607  1.00 73.12  ? 518 TYR G CD2 1 
ATOM   11023 C CE1 . TYR G 1 311 ? -20.801  20.686  23.654  1.00 66.92  ? 518 TYR G CE1 1 
ATOM   11024 C CE2 . TYR G 1 311 ? -20.878  22.985  23.015  1.00 75.87  ? 518 TYR G CE2 1 
ATOM   11025 C CZ  . TYR G 1 311 ? -21.500  21.870  23.544  1.00 73.87  ? 518 TYR G CZ  1 
ATOM   11026 O OH  . TYR G 1 311 ? -22.796  21.918  23.959  1.00 72.60  ? 518 TYR G OH  1 
ATOM   11027 N N   . ILE G 1 312 ? -15.601  22.458  19.890  1.00 72.47  ? 519 ILE G N   1 
ATOM   11028 C CA  . ILE G 1 312 ? -14.341  22.930  19.310  1.00 70.83  ? 519 ILE G CA  1 
ATOM   11029 C C   . ILE G 1 312 ? -14.105  24.374  19.736  1.00 70.00  ? 519 ILE G C   1 
ATOM   11030 O O   . ILE G 1 312 ? -15.013  25.206  19.644  1.00 69.80  ? 519 ILE G O   1 
ATOM   11031 C CB  . ILE G 1 312 ? -14.329  22.828  17.774  1.00 71.33  ? 519 ILE G CB  1 
ATOM   11032 C CG1 . ILE G 1 312 ? -14.555  21.390  17.323  1.00 60.08  ? 519 ILE G CG1 1 
ATOM   11033 C CG2 . ILE G 1 312 ? -13.014  23.378  17.208  1.00 68.00  ? 519 ILE G CG2 1 
ATOM   11034 C CD1 . ILE G 1 312 ? -14.283  21.177  15.855  1.00 52.37  ? 519 ILE G CD1 1 
ATOM   11035 N N   . ARG G 1 313 ? -12.882  24.668  20.190  1.00 69.72  ? 520 ARG G N   1 
ATOM   11036 C CA  . ARG G 1 313 ? -12.532  26.017  20.623  1.00 72.74  ? 520 ARG G CA  1 
ATOM   11037 C C   . ARG G 1 313 ? -12.599  26.998  19.452  1.00 76.34  ? 520 ARG G C   1 
ATOM   11038 O O   . ARG G 1 313 ? -12.010  26.761  18.388  1.00 73.78  ? 520 ARG G O   1 
ATOM   11039 C CB  . ARG G 1 313 ? -11.133  26.032  21.244  1.00 65.48  ? 520 ARG G CB  1 
ATOM   11040 N N   . GLU G 1 314 ? -13.308  28.115  19.664  1.00 74.02  ? 521 GLU G N   1 
ATOM   11041 C CA  . GLU G 1 314 ? -13.538  29.085  18.594  1.00 69.48  ? 521 GLU G CA  1 
ATOM   11042 C C   . GLU G 1 314 ? -12.231  29.562  17.974  1.00 67.92  ? 521 GLU G C   1 
ATOM   11043 O O   . GLU G 1 314 ? -12.122  29.704  16.751  1.00 62.30  ? 521 GLU G O   1 
ATOM   11044 C CB  . GLU G 1 314 ? -14.323  30.267  19.146  1.00 72.55  ? 521 GLU G CB  1 
ATOM   11045 C CG  . GLU G 1 314 ? -15.267  30.913  18.166  1.00 76.89  ? 521 GLU G CG  1 
ATOM   11046 C CD  . GLU G 1 314 ? -15.847  32.200  18.715  1.00 80.65  ? 521 GLU G CD  1 
ATOM   11047 O OE1 . GLU G 1 314 ? -16.387  32.207  19.844  1.00 78.06  ? 521 GLU G OE1 1 
ATOM   11048 O OE2 . GLU G 1 314 ? -15.732  33.221  18.015  1.00 95.99  ? 521 GLU G OE2 1 
ATOM   11049 N N   . SER G 1 315 ? -11.203  29.743  18.793  1.00 66.75  ? 522 SER G N   1 
ATOM   11050 C CA  . SER G 1 315 ? -9.922   30.281  18.273  1.00 66.13  ? 522 SER G CA  1 
ATOM   11051 C C   . SER G 1 315 ? -9.236   29.298  17.327  1.00 67.91  ? 522 SER G C   1 
ATOM   11052 O O   . SER G 1 315 ? -8.399   29.748  16.535  1.00 58.68  ? 522 SER G O   1 
ATOM   11053 C CB  . SER G 1 315 ? -9.009   30.619  19.401  1.00 67.77  ? 522 SER G CB  1 
ATOM   11054 O OG  . SER G 1 315 ? -8.427   29.451  19.958  1.00 77.24  ? 522 SER G OG  1 
ATOM   11055 N N   . LYS G 1 316 ? -9.567   28.011  17.408  1.00 68.45  ? 523 LYS G N   1 
ATOM   11056 C CA  . LYS G 1 316 ? -8.808   27.019  16.596  1.00 65.06  ? 523 LYS G CA  1 
ATOM   11057 C C   . LYS G 1 316 ? -9.654   26.336  15.522  1.00 65.00  ? 523 LYS G C   1 
ATOM   11058 O O   . LYS G 1 316 ? -9.111   25.460  14.845  1.00 62.37  ? 523 LYS G O   1 
ATOM   11059 C CB  . LYS G 1 316 ? -8.246   25.944  17.524  1.00 50.85  ? 523 LYS G CB  1 
ATOM   11060 N N   . LEU G 1 317 ? -10.908  26.741  15.347  1.00 70.25  ? 524 LEU G N   1 
ATOM   11061 C CA  . LEU G 1 317 ? -11.822  26.076  14.381  1.00 72.46  ? 524 LEU G CA  1 
ATOM   11062 C C   . LEU G 1 317 ? -11.187  26.003  12.991  1.00 74.34  ? 524 LEU G C   1 
ATOM   11063 O O   . LEU G 1 317 ? -11.288  24.945  12.373  1.00 77.58  ? 524 LEU G O   1 
ATOM   11064 C CB  . LEU G 1 317 ? -13.134  26.861  14.338  1.00 67.06  ? 524 LEU G CB  1 
ATOM   11065 C CG  . LEU G 1 317 ? -14.403  26.038  14.534  1.00 78.34  ? 524 LEU G CG  1 
ATOM   11066 C CD1 . LEU G 1 317 ? -15.127  26.471  15.796  1.00 68.68  ? 524 LEU G CD1 1 
ATOM   11067 C CD2 . LEU G 1 317 ? -15.317  26.166  13.328  1.00 70.47  ? 524 LEU G CD2 1 
ATOM   11068 N N   . SER G 1 318 ? -10.553  27.081  12.539  1.00 77.88  ? 525 SER G N   1 
ATOM   11069 C CA  . SER G 1 318 ? -9.956   27.128  11.181  1.00 72.39  ? 525 SER G CA  1 
ATOM   11070 C C   . SER G 1 318 ? -8.935   26.008  10.984  1.00 77.33  ? 525 SER G C   1 
ATOM   11071 O O   . SER G 1 318 ? -8.941   25.419  9.909   1.00 78.35  ? 525 SER G O   1 
ATOM   11072 C CB  . SER G 1 318 ? -9.323   28.464  10.936  1.00 75.13  ? 525 SER G CB  1 
ATOM   11073 O OG  . SER G 1 318 ? -8.324   28.740  11.905  1.00 81.85  ? 525 SER G OG  1 
ATOM   11074 N N   . GLU G 1 319 ? -8.073   25.760  11.967  1.00 77.61  ? 526 GLU G N   1 
ATOM   11075 C CA  . GLU G 1 319 ? -6.996   24.750  11.805  1.00 77.67  ? 526 GLU G CA  1 
ATOM   11076 C C   . GLU G 1 319 ? -7.586   23.345  11.911  1.00 79.34  ? 526 GLU G C   1 
ATOM   11077 O O   . GLU G 1 319 ? -7.200   22.495  11.110  1.00 78.95  ? 526 GLU G O   1 
ATOM   11078 C CB  . GLU G 1 319 ? -5.910   24.970  12.853  1.00 73.89  ? 526 GLU G CB  1 
ATOM   11079 C CG  . GLU G 1 319 ? -4.540   24.491  12.418  1.00 77.64  ? 526 GLU G CG  1 
ATOM   11080 C CD  . GLU G 1 319 ? -3.503   24.467  13.527  1.00 89.58  ? 526 GLU G CD  1 
ATOM   11081 O OE1 . GLU G 1 319 ? -2.439   23.858  13.322  1.00 87.33  ? 526 GLU G OE1 1 
ATOM   11082 O OE2 . GLU G 1 319 ? -3.761   25.059  14.591  1.00 85.73  ? 526 GLU G OE2 1 
ATOM   11083 N N   . VAL G 1 320 ? -8.471   23.121  12.878  1.00 75.43  ? 527 VAL G N   1 
ATOM   11084 C CA  . VAL G 1 320 ? -9.109   21.786  13.051  1.00 79.03  ? 527 VAL G CA  1 
ATOM   11085 C C   . VAL G 1 320 ? -9.905   21.473  11.785  1.00 85.76  ? 527 VAL G C   1 
ATOM   11086 O O   . VAL G 1 320 ? -9.710   20.394  11.218  1.00 83.10  ? 527 VAL G O   1 
ATOM   11087 C CB  . VAL G 1 320 ? -9.992   21.743  14.311  1.00 72.95  ? 527 VAL G CB  1 
ATOM   11088 C CG1 . VAL G 1 320 ? -10.629  20.377  14.504  1.00 73.63  ? 527 VAL G CG1 1 
ATOM   11089 C CG2 . VAL G 1 320 ? -9.221   22.144  15.556  1.00 68.13  ? 527 VAL G CG2 1 
ATOM   11090 N N   . LEU G 1 321 ? -10.749  22.405  11.351  1.00 88.69  ? 528 LEU G N   1 
ATOM   11091 C CA  . LEU G 1 321 ? -11.598  22.199  10.152  1.00 88.31  ? 528 LEU G CA  1 
ATOM   11092 C C   . LEU G 1 321 ? -10.865  22.673  8.895   1.00 90.05  ? 528 LEU G C   1 
ATOM   11093 O O   . LEU G 1 321 ? -11.554  22.978  7.909   1.00 87.69  ? 528 LEU G O   1 
ATOM   11094 C CB  . LEU G 1 321 ? -12.904  22.967  10.366  1.00 83.84  ? 528 LEU G CB  1 
ATOM   11095 N N   . GLN G 1 322 ? -9.530   22.737  8.921   1.00 88.37  ? 529 GLN G N   1 
ATOM   11096 C CA  . GLN G 1 322 ? -8.767   23.059  7.723   1.00 85.26  ? 529 GLN G CA  1 
ATOM   11097 C C   . GLN G 1 322 ? -9.270   22.221  6.562   1.00 90.16  ? 529 GLN G C   1 
ATOM   11098 O O   . GLN G 1 322 ? -9.508   21.018  6.708   1.00 91.32  ? 529 GLN G O   1 
ATOM   11099 C CB  . GLN G 1 322 ? -7.275   22.794  7.954   1.00 84.34  ? 529 GLN G CB  1 
ATOM   11100 N N   . ALA G 1 323 ? -9.452   22.867  5.411   1.00 92.34  ? 530 ALA G N   1 
ATOM   11101 C CA  . ALA G 1 323 ? -10.087  22.211  4.275   1.00 90.45  ? 530 ALA G CA  1 
ATOM   11102 C C   . ALA G 1 323 ? -9.213   21.080  3.740   1.00 82.65  ? 530 ALA G C   1 
ATOM   11103 O O   . ALA G 1 323 ? -7.982   21.158  3.758   1.00 78.15  ? 530 ALA G O   1 
ATOM   11104 C CB  . ALA G 1 323 ? -10.389  23.232  3.179   1.00 91.59  ? 530 ALA G CB  1 
ATOM   11105 N N   . VAL G 1 324 ? -9.863   19.986  3.347   1.00 91.85  ? 531 VAL G N   1 
ATOM   11106 C CA  . VAL G 1 324 ? -9.123   18.805  2.812   1.00 92.55  ? 531 VAL G CA  1 
ATOM   11107 C C   . VAL G 1 324 ? -9.654   18.512  1.406   1.00 86.11  ? 531 VAL G C   1 
ATOM   11108 O O   . VAL G 1 324 ? -10.880  18.629  1.221   1.00 88.72  ? 531 VAL G O   1 
ATOM   11109 C CB  . VAL G 1 324 ? -9.255   17.575  3.733   1.00 89.23  ? 531 VAL G CB  1 
ATOM   11110 C CG1 . VAL G 1 324 ? -8.769   16.304  3.056   1.00 82.33  ? 531 VAL G CG1 1 
ATOM   11111 C CG2 . VAL G 1 324 ? -8.544   17.766  5.063   1.00 85.63  ? 531 VAL G CG2 1 
ATOM   11112 N N   . MET H 2 1   ? -0.641   3.474   49.098  1.00 56.99  ? 1   MET H N   1 
ATOM   11113 C CA  . MET H 2 1   ? -0.879   4.826   48.608  1.00 58.65  ? 1   MET H CA  1 
ATOM   11114 C C   . MET H 2 1   ? -2.376   5.066   48.541  1.00 54.68  ? 1   MET H C   1 
ATOM   11115 O O   . MET H 2 1   ? -3.131   4.194   48.122  1.00 54.89  ? 1   MET H O   1 
ATOM   11116 C CB  . MET H 2 1   ? -0.222   5.048   47.231  1.00 43.93  ? 1   MET H CB  1 
ATOM   11117 C CG  . MET H 2 1   ? -0.486   3.930   46.288  1.00 54.94  ? 1   MET H CG  1 
ATOM   11118 S SD  . MET H 2 1   ? 0.148    4.214   44.653  1.00 62.33  ? 1   MET H SD  1 
ATOM   11119 C CE  . MET H 2 1   ? 1.726    4.924   45.087  1.00 60.56  ? 1   MET H CE  1 
ATOM   11120 N N   . GLN H 2 2   ? -2.782   6.275   48.928  1.00 49.52  ? 2   GLN H N   1 
ATOM   11121 C CA  . GLN H 2 2   ? -4.204   6.662   48.835  1.00 47.24  ? 2   GLN H CA  1 
ATOM   11122 C C   . GLN H 2 2   ? -4.439   7.339   47.497  1.00 53.13  ? 2   GLN H C   1 
ATOM   11123 O O   . GLN H 2 2   ? -3.946   8.459   47.306  1.00 57.03  ? 2   GLN H O   1 
ATOM   11124 C CB  . GLN H 2 2   ? -4.568   7.667   49.914  1.00 49.88  ? 2   GLN H CB  1 
ATOM   11125 C CG  . GLN H 2 2   ? -6.046   8.000   49.945  1.00 50.69  ? 2   GLN H CG  1 
ATOM   11126 C CD  . GLN H 2 2   ? -6.314   9.125   50.906  1.00 51.43  ? 2   GLN H CD  1 
ATOM   11127 O OE1 . GLN H 2 2   ? -6.064   10.289  50.612  1.00 55.76  ? 2   GLN H OE1 1 
ATOM   11128 N NE2 . GLN H 2 2   ? -6.823   8.775   52.073  1.00 47.87  ? 2   GLN H NE2 1 
ATOM   11129 N N   . ILE H 2 3   ? -5.157   6.665   46.610  1.00 44.06  ? 3   ILE H N   1 
ATOM   11130 C CA  . ILE H 2 3   ? -5.515   7.286   45.312  1.00 44.65  ? 3   ILE H CA  1 
ATOM   11131 C C   . ILE H 2 3   ? -6.930   7.837   45.419  1.00 48.02  ? 3   ILE H C   1 
ATOM   11132 O O   . ILE H 2 3   ? -7.579   7.655   46.456  1.00 49.17  ? 3   ILE H O   1 
ATOM   11133 C CB  . ILE H 2 3   ? -5.399   6.270   44.167  1.00 44.39  ? 3   ILE H CB  1 
ATOM   11134 C CG1 . ILE H 2 3   ? -6.302   5.057   44.389  1.00 42.89  ? 3   ILE H CG1 1 
ATOM   11135 C CG2 . ILE H 2 3   ? -3.951   5.867   43.959  1.00 51.36  ? 3   ILE H CG2 1 
ATOM   11136 C CD1 . ILE H 2 3   ? -6.888   4.502   43.124  1.00 39.71  ? 3   ILE H CD1 1 
ATOM   11137 N N   . PHE H 2 4   ? -7.376   8.495   44.362  1.00 42.71  ? 4   PHE H N   1 
ATOM   11138 C CA  . PHE H 2 4   ? -8.742   9.048   44.337  1.00 42.92  ? 4   PHE H CA  1 
ATOM   11139 C C   . PHE H 2 4   ? -9.512   8.476   43.157  1.00 43.45  ? 4   PHE H C   1 
ATOM   11140 O O   . PHE H 2 4   ? -8.945   8.336   42.089  1.00 44.54  ? 4   PHE H O   1 
ATOM   11141 C CB  . PHE H 2 4   ? -8.705   10.569  44.224  1.00 48.87  ? 4   PHE H CB  1 
ATOM   11142 C CG  . PHE H 2 4   ? -8.194   11.323  45.422  1.00 50.10  ? 4   PHE H CG  1 
ATOM   11143 C CD1 . PHE H 2 4   ? -8.720   11.103  46.683  1.00 48.69  ? 4   PHE H CD1 1 
ATOM   11144 C CD2 . PHE H 2 4   ? -7.207   12.282  45.277  1.00 50.29  ? 4   PHE H CD2 1 
ATOM   11145 C CE1 . PHE H 2 4   ? -8.253   11.814  47.776  1.00 55.28  ? 4   PHE H CE1 1 
ATOM   11146 C CE2 . PHE H 2 4   ? -6.743   12.993  46.371  1.00 50.06  ? 4   PHE H CE2 1 
ATOM   11147 C CZ  . PHE H 2 4   ? -7.266   12.756  47.618  1.00 53.25  ? 4   PHE H CZ  1 
ATOM   11148 N N   . VAL H 2 5   ? -10.747  8.068   43.386  1.00 41.06  ? 5   VAL H N   1 
ATOM   11149 C CA  . VAL H 2 5   ? -11.648  7.632   42.333  1.00 42.71  ? 5   VAL H CA  1 
ATOM   11150 C C   . VAL H 2 5   ? -12.853  8.559   42.359  1.00 44.86  ? 5   VAL H C   1 
ATOM   11151 O O   . VAL H 2 5   ? -13.463  8.766   43.421  1.00 45.25  ? 5   VAL H O   1 
ATOM   11152 C CB  . VAL H 2 5   ? -12.053  6.162   42.530  1.00 43.69  ? 5   VAL H CB  1 
ATOM   11153 C CG1 . VAL H 2 5   ? -12.876  5.679   41.380  1.00 42.96  ? 5   VAL H CG1 1 
ATOM   11154 C CG2 . VAL H 2 5   ? -10.817  5.316   42.677  1.00 41.73  ? 5   VAL H CG2 1 
ATOM   11155 N N   . LYS H 2 6   ? -13.145  9.171   41.213  1.00 43.35  ? 6   LYS H N   1 
ATOM   11156 C CA  . LYS H 2 6   ? -14.400  9.902   40.997  1.00 55.86  ? 6   LYS H CA  1 
ATOM   11157 C C   . LYS H 2 6   ? -15.483  8.906   40.554  1.00 50.76  ? 6   LYS H C   1 
ATOM   11158 O O   . LYS H 2 6   ? -15.397  8.328   39.463  1.00 50.67  ? 6   LYS H O   1 
ATOM   11159 C CB  . LYS H 2 6   ? -14.219  11.011  39.955  1.00 45.12  ? 6   LYS H CB  1 
ATOM   11160 N N   . THR H 2 7   ? -16.502  8.708   41.390  1.00 47.75  ? 7   THR H N   1 
ATOM   11161 C CA  . THR H 2 7   ? -17.533  7.707   41.116  1.00 58.62  ? 7   THR H CA  1 
ATOM   11162 C C   . THR H 2 7   ? -18.582  8.245   40.126  1.00 62.78  ? 7   THR H C   1 
ATOM   11163 O O   . THR H 2 7   ? -18.422  9.300   39.505  1.00 60.18  ? 7   THR H O   1 
ATOM   11164 C CB  . THR H 2 7   ? -18.195  7.239   42.413  1.00 56.65  ? 7   THR H CB  1 
ATOM   11165 O OG1 . THR H 2 7   ? -18.956  8.318   42.988  1.00 61.02  ? 7   THR H OG1 1 
ATOM   11166 C CG2 . THR H 2 7   ? -17.159  6.740   43.401  1.00 49.67  ? 7   THR H CG2 1 
ATOM   11167 N N   . LEU H 2 8   ? -19.685  7.504   39.965  1.00 65.61  ? 8   LEU H N   1 
ATOM   11168 C CA  . LEU H 2 8   ? -20.660  7.863   38.940  1.00 65.50  ? 8   LEU H CA  1 
ATOM   11169 C C   . LEU H 2 8   ? -21.370  9.165   39.267  1.00 64.80  ? 8   LEU H C   1 
ATOM   11170 O O   . LEU H 2 8   ? -21.714  9.927   38.353  1.00 67.47  ? 8   LEU H O   1 
ATOM   11171 C CB  . LEU H 2 8   ? -21.670  6.738   38.757  1.00 61.90  ? 8   LEU H CB  1 
ATOM   11172 C CG  . LEU H 2 8   ? -21.082  5.352   38.537  1.00 66.10  ? 8   LEU H CG  1 
ATOM   11173 C CD1 . LEU H 2 8   ? -22.203  4.320   38.507  1.00 70.16  ? 8   LEU H CD1 1 
ATOM   11174 C CD2 . LEU H 2 8   ? -20.281  5.320   37.238  1.00 60.65  ? 8   LEU H CD2 1 
ATOM   11175 N N   . THR H 2 9   ? -21.586  9.435   40.559  1.00 68.71  ? 9   THR H N   1 
ATOM   11176 C CA  . THR H 2 9   ? -22.233  10.657  41.025  1.00 65.88  ? 9   THR H CA  1 
ATOM   11177 C C   . THR H 2 9   ? -21.335  11.881  40.906  1.00 66.86  ? 9   THR H C   1 
ATOM   11178 O O   . THR H 2 9   ? -21.834  13.008  40.858  1.00 74.62  ? 9   THR H O   1 
ATOM   11179 C CB  . THR H 2 9   ? -22.669  10.482  42.484  1.00 69.63  ? 9   THR H CB  1 
ATOM   11180 O OG1 . THR H 2 9   ? -21.545  10.708  43.354  1.00 64.21  ? 9   THR H OG1 1 
ATOM   11181 C CG2 . THR H 2 9   ? -23.217  9.057   42.709  1.00 62.73  ? 9   THR H CG2 1 
ATOM   11182 N N   . GLY H 2 10  ? -20.029  11.694  40.842  1.00 67.93  ? 10  GLY H N   1 
ATOM   11183 C CA  . GLY H 2 10  ? -19.113  12.803  40.885  1.00 64.78  ? 10  GLY H CA  1 
ATOM   11184 C C   . GLY H 2 10  ? -18.450  13.004  42.225  1.00 56.59  ? 10  GLY H C   1 
ATOM   11185 O O   . GLY H 2 10  ? -17.524  13.811  42.318  1.00 64.68  ? 10  GLY H O   1 
ATOM   11186 N N   . LYS H 2 11  ? -18.894  12.306  43.265  1.00 58.27  ? 11  LYS H N   1 
ATOM   11187 C CA  . LYS H 2 11  ? -18.201  12.374  44.543  1.00 60.80  ? 11  LYS H CA  1 
ATOM   11188 C C   . LYS H 2 11  ? -16.832  11.696  44.428  1.00 63.39  ? 11  LYS H C   1 
ATOM   11189 O O   . LYS H 2 11  ? -16.713  10.590  43.885  1.00 64.92  ? 11  LYS H O   1 
ATOM   11190 C CB  . LYS H 2 11  ? -19.043  11.718  45.640  1.00 56.24  ? 11  LYS H CB  1 
ATOM   11191 N N   . THR H 2 12  ? -15.787  12.374  44.897  1.00 56.91  ? 12  THR H N   1 
ATOM   11192 C CA  . THR H 2 12  ? -14.482  11.739  44.996  1.00 55.05  ? 12  THR H CA  1 
ATOM   11193 C C   . THR H 2 12  ? -14.491  10.800  46.201  1.00 57.02  ? 12  THR H C   1 
ATOM   11194 O O   . THR H 2 12  ? -15.004  11.165  47.266  1.00 54.26  ? 12  THR H O   1 
ATOM   11195 C CB  . THR H 2 12  ? -13.372  12.789  45.125  1.00 50.53  ? 12  THR H CB  1 
ATOM   11196 O OG1 . THR H 2 12  ? -13.535  13.793  44.119  1.00 52.96  ? 12  THR H OG1 1 
ATOM   11197 C CG2 . THR H 2 12  ? -12.018  12.149  44.918  1.00 48.15  ? 12  THR H CG2 1 
ATOM   11198 N N   . ILE H 2 13  ? -13.963  9.582   46.027  1.00 45.45  ? 13  ILE H N   1 
ATOM   11199 C CA  . ILE H 2 13  ? -13.690  8.719   47.163  1.00 44.49  ? 13  ILE H CA  1 
ATOM   11200 C C   . ILE H 2 13  ? -12.201  8.401   47.210  1.00 48.39  ? 13  ILE H C   1 
ATOM   11201 O O   . ILE H 2 13  ? -11.469  8.520   46.221  1.00 48.13  ? 13  ILE H O   1 
ATOM   11202 C CB  . ILE H 2 13  ? -14.510  7.422   47.123  1.00 49.52  ? 13  ILE H CB  1 
ATOM   11203 C CG1 . ILE H 2 13  ? -14.055  6.533   45.961  1.00 52.19  ? 13  ILE H CG1 1 
ATOM   11204 C CG2 . ILE H 2 13  ? -15.965  7.745   46.985  1.00 52.88  ? 13  ILE H CG2 1 
ATOM   11205 C CD1 . ILE H 2 13  ? -14.613  5.138   45.994  1.00 49.90  ? 13  ILE H CD1 1 
ATOM   11206 N N   . THR H 2 14  ? -11.758  7.977   48.388  1.00 52.53  ? 14  THR H N   1 
ATOM   11207 C CA  . THR H 2 14  ? -10.409  7.464   48.563  1.00 52.38  ? 14  THR H CA  1 
ATOM   11208 C C   . THR H 2 14  ? -10.373  5.960   48.352  1.00 52.57  ? 14  THR H C   1 
ATOM   11209 O O   . THR H 2 14  ? -11.346  5.243   48.600  1.00 52.45  ? 14  THR H O   1 
ATOM   11210 C CB  . THR H 2 14  ? -9.885   7.801   49.957  1.00 48.40  ? 14  THR H CB  1 
ATOM   11211 O OG1 . THR H 2 14  ? -10.816  7.322   50.912  1.00 49.08  ? 14  THR H OG1 1 
ATOM   11212 C CG2 . THR H 2 14  ? -9.814   9.289   50.113  1.00 52.56  ? 14  THR H CG2 1 
ATOM   11213 N N   . LEU H 2 15  ? -9.239   5.478   47.849  1.00 52.85  ? 15  LEU H N   1 
ATOM   11214 C CA  . LEU H 2 15  ? -9.044   4.013   47.702  1.00 52.85  ? 15  LEU H CA  1 
ATOM   11215 C C   . LEU H 2 15  ? -7.614   3.679   48.120  1.00 54.64  ? 15  LEU H C   1 
ATOM   11216 O O   . LEU H 2 15  ? -6.697   4.417   47.750  1.00 49.46  ? 15  LEU H O   1 
ATOM   11217 C CB  . LEU H 2 15  ? -9.320   3.569   46.268  1.00 48.70  ? 15  LEU H CB  1 
ATOM   11218 C CG  . LEU H 2 15  ? -9.930   2.180   46.124  1.00 54.08  ? 15  LEU H CG  1 
ATOM   11219 C CD1 . LEU H 2 15  ? -11.416  2.209   46.432  1.00 53.79  ? 15  LEU H CD1 1 
ATOM   11220 C CD2 . LEU H 2 15  ? -9.692   1.645   44.727  1.00 53.34  ? 15  LEU H CD2 1 
ATOM   11221 N N   . GLU H 2 16  ? -7.448   2.594   48.867  1.00 55.60  ? 16  GLU H N   1 
ATOM   11222 C CA  . GLU H 2 16  ? -6.132   2.246   49.376  1.00 52.63  ? 16  GLU H CA  1 
ATOM   11223 C C   . GLU H 2 16  ? -5.579   1.084   48.572  1.00 56.92  ? 16  GLU H C   1 
ATOM   11224 O O   . GLU H 2 16  ? -5.937   -0.071  48.789  1.00 62.95  ? 16  GLU H O   1 
ATOM   11225 C CB  . GLU H 2 16  ? -6.178   1.957   50.869  1.00 49.26  ? 16  GLU H CB  1 
ATOM   11226 C CG  . GLU H 2 16  ? -5.820   3.167   51.658  1.00 59.46  ? 16  GLU H CG  1 
ATOM   11227 C CD  . GLU H 2 16  ? -4.392   3.529   51.406  1.00 71.72  ? 16  GLU H CD  1 
ATOM   11228 O OE1 . GLU H 2 16  ? -3.599   2.603   51.087  1.00 68.61  ? 16  GLU H OE1 1 
ATOM   11229 O OE2 . GLU H 2 16  ? -4.074   4.762   51.503  1.00 74.43  ? 16  GLU H OE2 1 
ATOM   11230 N N   . VAL H 2 17  ? -4.669   1.405   47.669  1.00 55.23  ? 17  VAL H N   1 
ATOM   11231 C CA  . VAL H 2 17  ? -4.093   0.431   46.766  1.00 58.88  ? 17  VAL H CA  1 
ATOM   11232 C C   . VAL H 2 17  ? -2.576   0.491   46.858  1.00 60.40  ? 17  VAL H C   1 
ATOM   11233 O O   . VAL H 2 17  ? -2.004   1.311   47.588  1.00 63.14  ? 17  VAL H O   1 
ATOM   11234 C CB  . VAL H 2 17  ? -4.558   0.699   45.333  1.00 55.56  ? 17  VAL H CB  1 
ATOM   11235 C CG1 . VAL H 2 17  ? -6.070   0.660   45.254  1.00 58.83  ? 17  VAL H CG1 1 
ATOM   11236 C CG2 . VAL H 2 17  ? -4.059   2.046   44.908  1.00 53.28  ? 17  VAL H CG2 1 
ATOM   11237 N N   . GLU H 2 18  ? -1.916   -0.397  46.140  1.00 53.60  ? 18  GLU H N   1 
ATOM   11238 C CA  . GLU H 2 18  ? -0.440   -0.393  46.132  1.00 59.28  ? 18  GLU H CA  1 
ATOM   11239 C C   . GLU H 2 18  ? -0.007   -0.267  44.678  1.00 59.13  ? 18  GLU H C   1 
ATOM   11240 O O   . GLU H 2 18  ? -0.743   -0.739  43.815  1.00 57.92  ? 18  GLU H O   1 
ATOM   11241 C CB  . GLU H 2 18  ? 0.073    -1.671  46.788  1.00 53.39  ? 18  GLU H CB  1 
ATOM   11242 C CG  . GLU H 2 18  ? 0.275    -1.543  48.282  1.00 55.40  ? 18  GLU H CG  1 
ATOM   11243 C CD  . GLU H 2 18  ? 1.571    -0.858  48.670  1.00 74.95  ? 18  GLU H CD  1 
ATOM   11244 O OE1 . GLU H 2 18  ? 2.643    -1.417  48.375  1.00 69.90  ? 18  GLU H OE1 1 
ATOM   11245 O OE2 . GLU H 2 18  ? 1.502    0.233   49.265  1.00 82.48  ? 18  GLU H OE2 1 
ATOM   11246 N N   . PRO H 2 19  ? 1.156    0.333   44.362  1.00 60.80  ? 19  PRO H N   1 
ATOM   11247 C CA  . PRO H 2 19  ? 1.625    0.384   42.984  1.00 58.75  ? 19  PRO H CA  1 
ATOM   11248 C C   . PRO H 2 19  ? 1.601    -0.995  42.321  1.00 61.02  ? 19  PRO H C   1 
ATOM   11249 O O   . PRO H 2 19  ? 1.461    -1.045  41.128  1.00 58.86  ? 19  PRO H O   1 
ATOM   11250 C CB  . PRO H 2 19  ? 3.085    0.782   43.150  1.00 54.99  ? 19  PRO H CB  1 
ATOM   11251 C CG  . PRO H 2 19  ? 3.120    1.591   44.416  1.00 57.54  ? 19  PRO H CG  1 
ATOM   11252 C CD  . PRO H 2 19  ? 2.068    0.973   45.306  1.00 59.97  ? 19  PRO H CD  1 
ATOM   11253 N N   . SER H 2 20  ? 1.743    -2.060  43.110  1.00 58.55  ? 20  SER H N   1 
ATOM   11254 C CA  . SER H 2 20  ? 1.785    -3.444  42.584  1.00 58.92  ? 20  SER H CA  1 
ATOM   11255 C C   . SER H 2 20  ? 0.389    -3.956  42.261  1.00 59.93  ? 20  SER H C   1 
ATOM   11256 O O   . SER H 2 20  ? 0.305    -4.967  41.559  1.00 63.84  ? 20  SER H O   1 
ATOM   11257 C CB  . SER H 2 20  ? 2.436    -4.342  43.581  1.00 57.51  ? 20  SER H CB  1 
ATOM   11258 O OG  . SER H 2 20  ? 1.744    -4.311  44.819  1.00 74.23  ? 20  SER H OG  1 
ATOM   11259 N N   . ASP H 2 21  ? -0.658   -3.283  42.732  1.00 55.74  ? 21  ASP H N   1 
ATOM   11260 C CA  . ASP H 2 21  ? -1.996   -3.828  42.534  1.00 55.41  ? 21  ASP H CA  1 
ATOM   11261 C C   . ASP H 2 21  ? -2.356   -3.846  41.059  1.00 55.16  ? 21  ASP H C   1 
ATOM   11262 O O   . ASP H 2 21  ? -2.099   -2.890  40.328  1.00 57.14  ? 21  ASP H O   1 
ATOM   11263 C CB  . ASP H 2 21  ? -3.041   -3.009  43.296  1.00 59.33  ? 21  ASP H CB  1 
ATOM   11264 C CG  . ASP H 2 21  ? -3.074   -3.325  44.781  1.00 59.31  ? 21  ASP H CG  1 
ATOM   11265 O OD1 . ASP H 2 21  ? -2.597   -4.418  45.165  1.00 64.18  ? 21  ASP H OD1 1 
ATOM   11266 O OD2 . ASP H 2 21  ? -3.565   -2.470  45.561  1.00 54.40  ? 21  ASP H OD2 1 
ATOM   11267 N N   . THR H 2 22  ? -2.942   -4.945  40.614  1.00 51.05  ? 22  THR H N   1 
ATOM   11268 C CA  . THR H 2 22  ? -3.415   -4.939  39.249  1.00 57.59  ? 22  THR H CA  1 
ATOM   11269 C C   . THR H 2 22  ? -4.756   -4.223  39.164  1.00 57.11  ? 22  THR H C   1 
ATOM   11270 O O   . THR H 2 22  ? -5.458   -4.017  40.163  1.00 58.32  ? 22  THR H O   1 
ATOM   11271 C CB  . THR H 2 22  ? -3.538   -6.359  38.696  1.00 60.06  ? 22  THR H CB  1 
ATOM   11272 O OG1 . THR H 2 22  ? -4.590   -7.055  39.378  1.00 60.86  ? 22  THR H OG1 1 
ATOM   11273 C CG2 . THR H 2 22  ? -2.222   -7.106  38.840  1.00 45.36  ? 22  THR H CG2 1 
ATOM   11274 N N   . ILE H 2 23  ? -5.100   -3.835  37.937  1.00 55.09  ? 23  ILE H N   1 
ATOM   11275 C CA  . ILE H 2 23  ? -6.356   -3.137  37.693  1.00 55.68  ? 23  ILE H CA  1 
ATOM   11276 C C   . ILE H 2 23  ? -7.533   -3.947  38.229  1.00 57.01  ? 23  ILE H C   1 
ATOM   11277 O O   . ILE H 2 23  ? -8.464   -3.396  38.828  1.00 57.54  ? 23  ILE H O   1 
ATOM   11278 C CB  . ILE H 2 23  ? -6.496   -2.830  36.192  1.00 55.76  ? 23  ILE H CB  1 
ATOM   11279 C CG1 . ILE H 2 23  ? -5.393   -1.855  35.740  1.00 55.39  ? 23  ILE H CG1 1 
ATOM   11280 C CG2 . ILE H 2 23  ? -7.872   -2.288  35.887  1.00 50.75  ? 23  ILE H CG2 1 
ATOM   11281 C CD1 . ILE H 2 23  ? -5.038   -0.764  36.758  1.00 52.51  ? 23  ILE H CD1 1 
ATOM   11282 N N   . GLU H 2 24  ? -7.493   -5.272  38.059  1.00 60.47  ? 24  GLU H N   1 
ATOM   11283 C CA  . GLU H 2 24  ? -8.523   -6.123  38.649  1.00 53.39  ? 24  GLU H CA  1 
ATOM   11284 C C   . GLU H 2 24  ? -8.552   -5.979  40.161  1.00 50.66  ? 24  GLU H C   1 
ATOM   11285 O O   . GLU H 2 24  ? -9.631   -5.954  40.758  1.00 49.02  ? 24  GLU H O   1 
ATOM   11286 C CB  . GLU H 2 24  ? -8.291   -7.578  38.263  1.00 57.73  ? 24  GLU H CB  1 
ATOM   11287 C CG  . GLU H 2 24  ? -8.299   -7.817  36.779  1.00 63.57  ? 24  GLU H CG  1 
ATOM   11288 C CD  . GLU H 2 24  ? -6.913   -8.081  36.252  1.00 67.07  ? 24  GLU H CD  1 
ATOM   11289 O OE1 . GLU H 2 24  ? -6.732   -9.015  35.434  1.00 69.24  ? 24  GLU H OE1 1 
ATOM   11290 O OE2 . GLU H 2 24  ? -6.002   -7.343  36.680  1.00 65.74  ? 24  GLU H OE2 1 
ATOM   11291 N N   . ASN H 2 25  ? -7.378   -5.874  40.798  1.00 49.36  ? 25  ASN H N   1 
ATOM   11292 C CA  . ASN H 2 25  ? -7.361   -5.645  42.243  1.00 56.68  ? 25  ASN H CA  1 
ATOM   11293 C C   . ASN H 2 25  ? -7.951   -4.288  42.595  1.00 58.48  ? 25  ASN H C   1 
ATOM   11294 O O   . ASN H 2 25  ? -8.592   -4.143  43.649  1.00 53.53  ? 25  ASN H O   1 
ATOM   11295 C CB  . ASN H 2 25  ? -5.949   -5.732  42.816  1.00 56.20  ? 25  ASN H CB  1 
ATOM   11296 C CG  . ASN H 2 25  ? -5.201   -6.929  42.322  1.00 67.63  ? 25  ASN H CG  1 
ATOM   11297 O OD1 . ASN H 2 25  ? -3.961   -6.903  42.215  1.00 65.60  ? 25  ASN H OD1 1 
ATOM   11298 N ND2 . ASN H 2 25  ? -5.940   -8.004  42.006  1.00 70.71  ? 25  ASN H ND2 1 
ATOM   11299 N N   . VAL H 2 26  ? -7.722   -3.279  41.755  1.00 53.58  ? 26  VAL H N   1 
ATOM   11300 C CA  . VAL H 2 26  ? -8.317   -1.934  42.008  1.00 52.94  ? 26  VAL H CA  1 
ATOM   11301 C C   . VAL H 2 26  ? -9.833   -2.042  41.867  1.00 50.38  ? 26  VAL H C   1 
ATOM   11302 O O   . VAL H 2 26  ? -10.531  -1.505  42.722  1.00 51.89  ? 26  VAL H O   1 
ATOM   11303 C CB  . VAL H 2 26  ? -7.732   -0.858  41.080  1.00 53.43  ? 26  VAL H CB  1 
ATOM   11304 C CG1 . VAL H 2 26  ? -8.206   0.538   41.442  1.00 48.37  ? 26  VAL H CG1 1 
ATOM   11305 C CG2 . VAL H 2 26  ? -6.220   -0.912  41.068  1.00 52.63  ? 26  VAL H CG2 1 
ATOM   11306 N N   . LYS H 2 27  ? -10.309  -2.729  40.831  1.00 50.48  ? 27  LYS H N   1 
ATOM   11307 C CA  . LYS H 2 27  ? -11.746  -2.868  40.636  1.00 48.18  ? 27  LYS H CA  1 
ATOM   11308 C C   . LYS H 2 27  ? -12.379  -3.588  41.812  1.00 47.87  ? 27  LYS H C   1 
ATOM   11309 O O   . LYS H 2 27  ? -13.452  -3.192  42.284  1.00 51.46  ? 27  LYS H O   1 
ATOM   11310 C CB  . LYS H 2 27  ? -12.034  -3.605  39.328  1.00 49.98  ? 27  LYS H CB  1 
ATOM   11311 C CG  . LYS H 2 27  ? -11.648  -2.837  38.074  1.00 49.35  ? 27  LYS H CG  1 
ATOM   11312 C CD  . LYS H 2 27  ? -11.899  -3.642  36.805  1.00 49.34  ? 27  LYS H CD  1 
ATOM   11313 C CE  . LYS H 2 27  ? -11.623  -2.820  35.555  1.00 44.91  ? 27  LYS H CE  1 
ATOM   11314 N NZ  . LYS H 2 27  ? -11.566  -3.633  34.317  1.00 44.64  ? 27  LYS H NZ  1 
ATOM   11315 N N   . ALA H 2 28  ? -11.720  -4.638  42.312  1.00 52.02  ? 28  ALA H N   1 
ATOM   11316 C CA  . ALA H 2 28  ? -12.225  -5.313  43.505  1.00 48.59  ? 28  ALA H CA  1 
ATOM   11317 C C   . ALA H 2 28  ? -12.385  -4.321  44.644  1.00 52.79  ? 28  ALA H C   1 
ATOM   11318 O O   . ALA H 2 28  ? -13.418  -4.308  45.324  1.00 54.31  ? 28  ALA H O   1 
ATOM   11319 C CB  . ALA H 2 28  ? -11.295  -6.457  43.923  1.00 33.70  ? 28  ALA H CB  1 
ATOM   11320 N N   . LYS H 2 29  ? -11.393  -3.467  44.845  1.00 48.42  ? 29  LYS H N   1 
ATOM   11321 C CA  . LYS H 2 29  ? -11.462  -2.506  45.969  1.00 51.41  ? 29  LYS H CA  1 
ATOM   11322 C C   . LYS H 2 29  ? -12.612  -1.531  45.716  1.00 48.82  ? 29  LYS H C   1 
ATOM   11323 O O   . LYS H 2 29  ? -13.261  -1.151  46.690  1.00 48.59  ? 29  LYS H O   1 
ATOM   11324 C CB  . LYS H 2 29  ? -10.098  -1.845  46.142  1.00 53.70  ? 29  LYS H CB  1 
ATOM   11325 C CG  . LYS H 2 29  ? -9.102   -2.642  46.968  1.00 56.81  ? 29  LYS H CG  1 
ATOM   11326 C CD  . LYS H 2 29  ? -7.672   -2.282  46.669  1.00 56.68  ? 29  LYS H CD  1 
ATOM   11327 C CE  . LYS H 2 29  ? -6.692   -3.367  47.054  1.00 50.69  ? 29  LYS H CE  1 
ATOM   11328 N NZ  . LYS H 2 29  ? -5.592   -2.836  47.890  1.00 56.06  ? 29  LYS H NZ  1 
ATOM   11329 N N   . ILE H 2 30  ? -12.859  -1.155  44.463  1.00 44.51  ? 30  ILE H N   1 
ATOM   11330 C CA  . ILE H 2 30  ? -14.014  -0.320  44.163  1.00 51.17  ? 30  ILE H CA  1 
ATOM   11331 C C   . ILE H 2 30  ? -15.316  -1.066  44.454  1.00 52.39  ? 30  ILE H C   1 
ATOM   11332 O O   . ILE H 2 30  ? -16.310  -0.460  44.888  1.00 46.36  ? 30  ILE H O   1 
ATOM   11333 C CB  . ILE H 2 30  ? -13.923  0.178   42.709  1.00 46.87  ? 30  ILE H CB  1 
ATOM   11334 C CG1 . ILE H 2 30  ? -12.817  1.223   42.615  1.00 43.41  ? 30  ILE H CG1 1 
ATOM   11335 C CG2 . ILE H 2 30  ? -15.231  0.775   42.255  1.00 43.41  ? 30  ILE H CG2 1 
ATOM   11336 C CD1 . ILE H 2 30  ? -12.341  1.466   41.247  1.00 43.15  ? 30  ILE H CD1 1 
ATOM   11337 N N   . GLN H 2 31  ? -15.330  -2.389  44.260  1.00 52.68  ? 31  GLN H N   1 
ATOM   11338 C CA  . GLN H 2 31  ? -16.535  -3.151  44.568  1.00 53.16  ? 31  GLN H CA  1 
ATOM   11339 C C   . GLN H 2 31  ? -16.775  -3.233  46.078  1.00 57.09  ? 31  GLN H C   1 
ATOM   11340 O O   . GLN H 2 31  ? -17.923  -3.116  46.536  1.00 52.27  ? 31  GLN H O   1 
ATOM   11341 C CB  . GLN H 2 31  ? -16.450  -4.544  43.943  1.00 47.89  ? 31  GLN H CB  1 
ATOM   11342 C CG  . GLN H 2 31  ? -17.669  -5.418  44.254  1.00 58.20  ? 31  GLN H CG  1 
ATOM   11343 C CD  . GLN H 2 31  ? -17.570  -6.822  43.677  1.00 58.69  ? 31  GLN H CD  1 
ATOM   11344 O OE1 . GLN H 2 31  ? -16.483  -7.404  43.595  1.00 54.56  ? 31  GLN H OE1 1 
ATOM   11345 N NE2 . GLN H 2 31  ? -18.709  -7.362  43.248  1.00 54.95  ? 31  GLN H NE2 1 
ATOM   11346 N N   . ASP H 2 32  ? -15.708  -3.430  46.871  1.00 55.60  ? 32  ASP H N   1 
ATOM   11347 C CA  . ASP H 2 32  ? -15.859  -3.420  48.324  1.00 49.59  ? 32  ASP H CA  1 
ATOM   11348 C C   . ASP H 2 32  ? -16.389  -2.077  48.811  1.00 51.57  ? 32  ASP H C   1 
ATOM   11349 O O   . ASP H 2 32  ? -17.208  -2.024  49.733  1.00 51.54  ? 32  ASP H O   1 
ATOM   11350 C CB  . ASP H 2 32  ? -14.523  -3.743  49.005  1.00 55.04  ? 32  ASP H CB  1 
ATOM   11351 C CG  . ASP H 2 32  ? -14.595  -3.681  50.565  1.00 67.23  ? 32  ASP H CG  1 
ATOM   11352 O OD1 . ASP H 2 32  ? -15.084  -4.652  51.207  1.00 69.60  ? 32  ASP H OD1 1 
ATOM   11353 O OD2 . ASP H 2 32  ? -14.133  -2.668  51.155  1.00 59.82  ? 32  ASP H OD2 1 
ATOM   11354 N N   . LYS H 2 33  ? -15.944  -0.977  48.204  1.00 53.11  ? 33  LYS H N   1 
ATOM   11355 C CA  . LYS H 2 33  ? -16.296  0.332   48.728  1.00 47.60  ? 33  LYS H CA  1 
ATOM   11356 C C   . LYS H 2 33  ? -17.498  0.954   48.036  1.00 47.28  ? 33  LYS H C   1 
ATOM   11357 O O   . LYS H 2 33  ? -18.350  1.531   48.709  1.00 52.12  ? 33  LYS H O   1 
ATOM   11358 C CB  . LYS H 2 33  ? -15.091  1.271   48.642  1.00 53.29  ? 33  LYS H CB  1 
ATOM   11359 C CG  . LYS H 2 33  ? -15.221  2.531   49.501  1.00 54.00  ? 33  LYS H CG  1 
ATOM   11360 C CD  . LYS H 2 33  ? -13.988  3.460   49.374  1.00 56.69  ? 33  LYS H CD  1 
ATOM   11361 C CE  . LYS H 2 33  ? -13.512  3.970   50.759  1.00 60.38  ? 33  LYS H CE  1 
ATOM   11362 N NZ  . LYS H 2 33  ? -12.887  5.336   50.799  1.00 51.45  ? 33  LYS H NZ  1 
ATOM   11363 N N   . GLU H 2 34  ? -17.608  0.848   46.715  1.00 49.19  ? 34  GLU H N   1 
ATOM   11364 C CA  . GLU H 2 34  ? -18.719  1.448   45.996  1.00 48.85  ? 34  GLU H CA  1 
ATOM   11365 C C   . GLU H 2 34  ? -19.738  0.443   45.507  1.00 54.23  ? 34  GLU H C   1 
ATOM   11366 O O   . GLU H 2 34  ? -20.774  0.859   44.982  1.00 61.40  ? 34  GLU H O   1 
ATOM   11367 C CB  . GLU H 2 34  ? -18.231  2.242   44.775  1.00 49.40  ? 34  GLU H CB  1 
ATOM   11368 C CG  . GLU H 2 34  ? -17.863  3.655   45.073  1.00 56.72  ? 34  GLU H CG  1 
ATOM   11369 C CD  . GLU H 2 34  ? -19.030  4.484   45.573  1.00 58.51  ? 34  GLU H CD  1 
ATOM   11370 O OE1 . GLU H 2 34  ? -19.980  4.758   44.791  1.00 50.82  ? 34  GLU H OE1 1 
ATOM   11371 O OE2 . GLU H 2 34  ? -18.976  4.859   46.764  1.00 57.48  ? 34  GLU H OE2 1 
ATOM   11372 N N   . GLY H 2 35  ? -19.459  -0.854  45.605  1.00 53.14  ? 35  GLY H N   1 
ATOM   11373 C CA  . GLY H 2 35  ? -20.424  -1.863  45.221  1.00 51.65  ? 35  GLY H CA  1 
ATOM   11374 C C   . GLY H 2 35  ? -20.555  -2.118  43.738  1.00 57.84  ? 35  GLY H C   1 
ATOM   11375 O O   . GLY H 2 35  ? -21.248  -3.065  43.352  1.00 60.59  ? 35  GLY H O   1 
ATOM   11376 N N   . ILE H 2 36  ? -19.937  -1.300  42.895  1.00 56.90  ? 36  ILE H N   1 
ATOM   11377 C CA  . ILE H 2 36  ? -19.935  -1.515  41.451  1.00 58.32  ? 36  ILE H CA  1 
ATOM   11378 C C   . ILE H 2 36  ? -19.279  -2.862  41.160  1.00 52.21  ? 36  ILE H C   1 
ATOM   11379 O O   . ILE H 2 36  ? -18.131  -3.079  41.562  1.00 54.88  ? 36  ILE H O   1 
ATOM   11380 C CB  . ILE H 2 36  ? -19.202  -0.370  40.734  1.00 57.81  ? 36  ILE H CB  1 
ATOM   11381 C CG1 . ILE H 2 36  ? -19.537  0.969   41.389  1.00 56.53  ? 36  ILE H CG1 1 
ATOM   11382 C CG2 . ILE H 2 36  ? -19.555  -0.349  39.266  1.00 54.92  ? 36  ILE H CG2 1 
ATOM   11383 C CD1 . ILE H 2 36  ? -21.006  1.308   41.317  1.00 70.88  ? 36  ILE H CD1 1 
ATOM   11384 N N   . PRO H 2 37  ? -19.951  -3.805  40.513  1.00 56.82  ? 37  PRO H N   1 
ATOM   11385 C CA  . PRO H 2 37  ? -19.303  -5.081  40.207  1.00 55.05  ? 37  PRO H CA  1 
ATOM   11386 C C   . PRO H 2 37  ? -18.156  -4.858  39.241  1.00 56.13  ? 37  PRO H C   1 
ATOM   11387 O O   . PRO H 2 37  ? -18.301  -4.097  38.270  1.00 58.42  ? 37  PRO H O   1 
ATOM   11388 C CB  . PRO H 2 37  ? -20.426  -5.910  39.560  1.00 53.44  ? 37  PRO H CB  1 
ATOM   11389 C CG  . PRO H 2 37  ? -21.678  -5.184  39.832  1.00 54.40  ? 37  PRO H CG  1 
ATOM   11390 C CD  . PRO H 2 37  ? -21.333  -3.753  40.008  1.00 62.57  ? 37  PRO H CD  1 
ATOM   11391 N N   . PRO H 2 38  ? -17.007  -5.500  39.470  1.00 51.42  ? 38  PRO H N   1 
ATOM   11392 C CA  . PRO H 2 38  ? -15.821  -5.221  38.642  1.00 52.53  ? 38  PRO H CA  1 
ATOM   11393 C C   . PRO H 2 38  ? -16.047  -5.420  37.159  1.00 54.47  ? 38  PRO H C   1 
ATOM   11394 O O   . PRO H 2 38  ? -15.330  -4.815  36.351  1.00 54.22  ? 38  PRO H O   1 
ATOM   11395 C CB  . PRO H 2 38  ? -14.774  -6.202  39.185  1.00 51.95  ? 38  PRO H CB  1 
ATOM   11396 C CG  . PRO H 2 38  ? -15.219  -6.460  40.596  1.00 54.43  ? 38  PRO H CG  1 
ATOM   11397 C CD  . PRO H 2 38  ? -16.714  -6.428  40.567  1.00 56.64  ? 38  PRO H CD  1 
ATOM   11398 N N   . ASP H 2 39  ? -17.028  -6.239  36.778  1.00 57.16  ? 39  ASP H N   1 
ATOM   11399 C CA  . ASP H 2 39  ? -17.311  -6.498  35.371  1.00 62.99  ? 39  ASP H CA  1 
ATOM   11400 C C   . ASP H 2 39  ? -17.853  -5.269  34.647  1.00 57.54  ? 39  ASP H C   1 
ATOM   11401 O O   . ASP H 2 39  ? -17.698  -5.170  33.430  1.00 56.28  ? 39  ASP H O   1 
ATOM   11402 C CB  . ASP H 2 39  ? -18.302  -7.672  35.250  1.00 67.53  ? 39  ASP H CB  1 
ATOM   11403 C CG  . ASP H 2 39  ? -17.842  -8.936  36.027  1.00 78.61  ? 39  ASP H CG  1 
ATOM   11404 O OD1 . ASP H 2 39  ? -17.841  -8.940  37.301  1.00 72.30  ? 39  ASP H OD1 1 
ATOM   11405 O OD2 . ASP H 2 39  ? -17.495  -9.938  35.353  1.00 77.21  ? 39  ASP H OD2 1 
ATOM   11406 N N   . GLN H 2 40  ? -18.446  -4.320  35.370  1.00 55.43  ? 40  GLN H N   1 
ATOM   11407 C CA  . GLN H 2 40  ? -19.060  -3.145  34.767  1.00 55.80  ? 40  GLN H CA  1 
ATOM   11408 C C   . GLN H 2 40  ? -18.194  -1.886  34.853  1.00 57.86  ? 40  GLN H C   1 
ATOM   11409 O O   . GLN H 2 40  ? -18.522  -0.882  34.205  1.00 51.48  ? 40  GLN H O   1 
ATOM   11410 C CB  . GLN H 2 40  ? -20.425  -2.881  35.425  1.00 52.09  ? 40  GLN H CB  1 
ATOM   11411 N N   . GLN H 2 41  ? -17.103  -1.920  35.621  1.00 54.53  ? 41  GLN H N   1 
ATOM   11412 C CA  . GLN H 2 41  ? -16.245  -0.759  35.804  1.00 50.97  ? 41  GLN H CA  1 
ATOM   11413 C C   . GLN H 2 41  ? -15.321  -0.544  34.611  1.00 51.58  ? 41  GLN H C   1 
ATOM   11414 O O   . GLN H 2 41  ? -14.755  -1.494  34.057  1.00 53.14  ? 41  GLN H O   1 
ATOM   11415 C CB  . GLN H 2 41  ? -15.394  -0.922  37.061  1.00 48.40  ? 41  GLN H CB  1 
ATOM   11416 C CG  . GLN H 2 41  ? -16.148  -1.375  38.280  1.00 50.94  ? 41  GLN H CG  1 
ATOM   11417 C CD  . GLN H 2 41  ? -15.218  -1.544  39.469  1.00 53.04  ? 41  GLN H CD  1 
ATOM   11418 O OE1 . GLN H 2 41  ? -14.089  -1.051  39.446  1.00 53.82  ? 41  GLN H OE1 1 
ATOM   11419 N NE2 . GLN H 2 41  ? -15.676  -2.252  40.504  1.00 46.98  ? 41  GLN H NE2 1 
ATOM   11420 N N   . ARG H 2 42  ? -15.150  0.724   34.243  1.00 50.86  ? 42  ARG H N   1 
ATOM   11421 C CA  . ARG H 2 42  ? -14.074  1.184   33.370  1.00 47.92  ? 42  ARG H CA  1 
ATOM   11422 C C   . ARG H 2 42  ? -13.405  2.376   34.045  1.00 50.12  ? 42  ARG H C   1 
ATOM   11423 O O   . ARG H 2 42  ? -14.087  3.279   34.539  1.00 53.27  ? 42  ARG H O   1 
ATOM   11424 C CB  . ARG H 2 42  ? -14.602  1.557   31.985  1.00 45.91  ? 42  ARG H CB  1 
ATOM   11425 C CG  . ARG H 2 42  ? -15.529  0.508   31.376  1.00 51.11  ? 42  ARG H CG  1 
ATOM   11426 C CD  . ARG H 2 42  ? -16.274  1.033   30.154  1.00 52.14  ? 42  ARG H CD  1 
ATOM   11427 N NE  . ARG H 2 42  ? -15.440  1.995   29.455  1.00 56.75  ? 42  ARG H NE  1 
ATOM   11428 C CZ  . ARG H 2 42  ? -15.885  3.104   28.879  1.00 56.74  ? 42  ARG H CZ  1 
ATOM   11429 N NH1 . ARG H 2 42  ? -17.180  3.393   28.885  1.00 56.22  ? 42  ARG H NH1 1 
ATOM   11430 N NH2 . ARG H 2 42  ? -15.019  3.924   28.302  1.00 58.46  ? 42  ARG H NH2 1 
ATOM   11431 N N   . LEU H 2 43  ? -12.080  2.369   34.094  1.00 48.20  ? 43  LEU H N   1 
ATOM   11432 C CA  . LEU H 2 43  ? -11.317  3.340   34.866  1.00 47.85  ? 43  LEU H CA  1 
ATOM   11433 C C   . LEU H 2 43  ? -10.463  4.136   33.907  1.00 52.67  ? 43  LEU H C   1 
ATOM   11434 O O   . LEU H 2 43  ? -9.543   3.588   33.291  1.00 52.09  ? 43  LEU H O   1 
ATOM   11435 C CB  . LEU H 2 43  ? -10.430  2.658   35.908  1.00 49.68  ? 43  LEU H CB  1 
ATOM   11436 C CG  . LEU H 2 43  ? -11.184  1.819   36.939  1.00 53.88  ? 43  LEU H CG  1 
ATOM   11437 C CD1 . LEU H 2 43  ? -10.235  0.940   37.714  1.00 45.01  ? 43  LEU H CD1 1 
ATOM   11438 C CD2 . LEU H 2 43  ? -12.004  2.725   37.873  1.00 58.78  ? 43  LEU H CD2 1 
ATOM   11439 N N   . ILE H 2 44  ? -10.754  5.423   33.790  1.00 57.02  ? 44  ILE H N   1 
ATOM   11440 C CA  . ILE H 2 44  ? -10.018  6.290   32.883  1.00 56.59  ? 44  ILE H CA  1 
ATOM   11441 C C   . ILE H 2 44  ? -9.049   7.138   33.689  1.00 57.50  ? 44  ILE H C   1 
ATOM   11442 O O   . ILE H 2 44  ? -9.457   7.857   34.611  1.00 59.44  ? 44  ILE H O   1 
ATOM   11443 C CB  . ILE H 2 44  ? -10.968  7.150   32.042  1.00 51.96  ? 44  ILE H CB  1 
ATOM   11444 C CG1 . ILE H 2 44  ? -11.731  6.219   31.105  1.00 51.56  ? 44  ILE H CG1 1 
ATOM   11445 C CG2 . ILE H 2 44  ? -10.184  8.158   31.213  1.00 50.14  ? 44  ILE H CG2 1 
ATOM   11446 C CD1 . ILE H 2 44  ? -13.179  6.117   31.402  1.00 59.21  ? 44  ILE H CD1 1 
ATOM   11447 N N   . PHE H 2 45  ? -7.770   7.034   33.323  1.00 55.38  ? 45  PHE H N   1 
ATOM   11448 C CA  . PHE H 2 45  ? -6.715   7.886   33.912  1.00 49.27  ? 45  PHE H CA  1 
ATOM   11449 C C   . PHE H 2 45  ? -5.905   8.432   32.737  1.00 53.71  ? 45  PHE H C   1 
ATOM   11450 O O   . PHE H 2 45  ? -5.395   7.610   31.966  1.00 54.45  ? 45  PHE H O   1 
ATOM   11451 C CB  . PHE H 2 45  ? -5.824   7.091   34.864  1.00 48.07  ? 45  PHE H CB  1 
ATOM   11452 C CG  . PHE H 2 45  ? -4.639   7.839   35.416  1.00 52.30  ? 45  PHE H CG  1 
ATOM   11453 C CD1 . PHE H 2 45  ? -4.786   8.693   36.494  1.00 51.19  ? 45  PHE H CD1 1 
ATOM   11454 C CD2 . PHE H 2 45  ? -3.377   7.681   34.867  1.00 51.18  ? 45  PHE H CD2 1 
ATOM   11455 C CE1 . PHE H 2 45  ? -3.698   9.381   37.004  1.00 51.36  ? 45  PHE H CE1 1 
ATOM   11456 C CE2 . PHE H 2 45  ? -2.291   8.372   35.376  1.00 44.26  ? 45  PHE H CE2 1 
ATOM   11457 C CZ  . PHE H 2 45  ? -2.453   9.217   36.446  1.00 45.60  ? 45  PHE H CZ  1 
ATOM   11458 N N   . ALA H 2 46  ? -5.838   9.753   32.578  1.00 53.61  ? 46  ALA H N   1 
ATOM   11459 C CA  . ALA H 2 46  ? -5.029   10.408  31.518  1.00 54.15  ? 46  ALA H CA  1 
ATOM   11460 C C   . ALA H 2 46  ? -5.387   9.912   30.117  1.00 54.24  ? 46  ALA H C   1 
ATOM   11461 O O   . ALA H 2 46  ? -4.461   9.628   29.345  1.00 52.26  ? 46  ALA H O   1 
ATOM   11462 C CB  . ALA H 2 46  ? -3.560   10.263  31.815  1.00 47.97  ? 46  ALA H CB  1 
ATOM   11463 N N   . GLY H 2 47  ? -6.677   9.868   29.795  1.00 52.96  ? 47  GLY H N   1 
ATOM   11464 C CA  . GLY H 2 47  ? -7.128   9.474   28.449  1.00 51.06  ? 47  GLY H CA  1 
ATOM   11465 C C   . GLY H 2 47  ? -6.912   8.013   28.141  1.00 53.99  ? 47  GLY H C   1 
ATOM   11466 O O   . GLY H 2 47  ? -7.262   7.597   27.033  1.00 58.02  ? 47  GLY H O   1 
ATOM   11467 N N   . LYS H 2 48  ? -6.344   7.261   29.081  1.00 55.61  ? 48  LYS H N   1 
ATOM   11468 C CA  . LYS H 2 48  ? -6.176   5.831   28.858  1.00 56.59  ? 48  LYS H CA  1 
ATOM   11469 C C   . LYS H 2 48  ? -7.184   5.076   29.711  1.00 52.11  ? 48  LYS H C   1 
ATOM   11470 O O   . LYS H 2 48  ? -7.349   5.382   30.892  1.00 55.92  ? 48  LYS H O   1 
ATOM   11471 C CB  . LYS H 2 48  ? -4.746   5.388   29.199  1.00 43.60  ? 48  LYS H CB  1 
ATOM   11472 N N   . GLN H 2 49  ? -7.884   4.124   29.111  1.00 48.19  ? 49  GLN H N   1 
ATOM   11473 C CA  . GLN H 2 49  ? -8.645   3.171   29.904  1.00 49.49  ? 49  GLN H CA  1 
ATOM   11474 C C   . GLN H 2 49  ? -7.695   2.105   30.422  1.00 47.64  ? 49  GLN H C   1 
ATOM   11475 O O   . GLN H 2 49  ? -6.946   1.509   29.647  1.00 54.83  ? 49  GLN H O   1 
ATOM   11476 C CB  . GLN H 2 49  ? -9.752   2.522   29.088  1.00 49.06  ? 49  GLN H CB  1 
ATOM   11477 C CG  . GLN H 2 49  ? -10.539  1.486   29.876  1.00 48.39  ? 49  GLN H CG  1 
ATOM   11478 C CD  . GLN H 2 49  ? -11.823  1.082   29.190  1.00 48.44  ? 49  GLN H CD  1 
ATOM   11479 O OE1 . GLN H 2 49  ? -12.765  1.874   29.077  1.00 50.25  ? 49  GLN H OE1 1 
ATOM   11480 N NE2 . GLN H 2 49  ? -11.865  -0.155  28.713  1.00 42.55  ? 49  GLN H NE2 1 
ATOM   11481 N N   . LEU H 2 50  ? -7.689   1.898   31.731  1.00 44.93  ? 50  LEU H N   1 
ATOM   11482 C CA  . LEU H 2 50  ? -6.777   0.931   32.305  1.00 49.25  ? 50  LEU H CA  1 
ATOM   11483 C C   . LEU H 2 50  ? -7.284   -0.470  32.001  1.00 56.59  ? 50  LEU H C   1 
ATOM   11484 O O   . LEU H 2 50  ? -8.482   -0.689  31.798  1.00 53.97  ? 50  LEU H O   1 
ATOM   11485 C CB  . LEU H 2 50  ? -6.642   1.153   33.804  1.00 52.78  ? 50  LEU H CB  1 
ATOM   11486 C CG  . LEU H 2 50  ? -6.612   2.629   34.207  1.00 50.96  ? 50  LEU H CG  1 
ATOM   11487 C CD1 . LEU H 2 50  ? -6.722   2.787   35.713  1.00 49.03  ? 50  LEU H CD1 1 
ATOM   11488 C CD2 . LEU H 2 50  ? -5.352   3.306   33.697  1.00 52.19  ? 50  LEU H CD2 1 
ATOM   11489 N N   . GLU H 2 51  ? -6.355   -1.418  31.941  1.00 61.02  ? 51  GLU H N   1 
ATOM   11490 C CA  . GLU H 2 51  ? -6.608   -2.723  31.347  1.00 62.19  ? 51  GLU H CA  1 
ATOM   11491 C C   . GLU H 2 51  ? -6.330   -3.826  32.351  1.00 62.92  ? 51  GLU H C   1 
ATOM   11492 O O   . GLU H 2 51  ? -5.259   -3.853  32.974  1.00 60.42  ? 51  GLU H O   1 
ATOM   11493 C CB  . GLU H 2 51  ? -5.750   -2.933  30.100  1.00 63.77  ? 51  GLU H CB  1 
ATOM   11494 C CG  . GLU H 2 51  ? -6.328   -2.291  28.859  1.00 64.96  ? 51  GLU H CG  1 
ATOM   11495 C CD  . GLU H 2 51  ? -5.355   -2.304  27.707  1.00 76.46  ? 51  GLU H CD  1 
ATOM   11496 O OE1 . GLU H 2 51  ? -5.818   -2.358  26.543  1.00 78.55  ? 51  GLU H OE1 1 
ATOM   11497 O OE2 . GLU H 2 51  ? -4.127   -2.265  27.972  1.00 73.17  ? 51  GLU H OE2 1 
ATOM   11498 N N   . ASP H 2 52  ? -7.298   -4.725  32.504  1.00 62.24  ? 52  ASP H N   1 
ATOM   11499 C CA  . ASP H 2 52  ? -7.096   -5.898  33.338  1.00 66.34  ? 52  ASP H CA  1 
ATOM   11500 C C   . ASP H 2 52  ? -5.841   -6.619  32.887  1.00 70.72  ? 52  ASP H C   1 
ATOM   11501 O O   . ASP H 2 52  ? -5.732   -7.039  31.728  1.00 65.35  ? 52  ASP H O   1 
ATOM   11502 C CB  . ASP H 2 52  ? -8.306   -6.830  33.256  1.00 63.07  ? 52  ASP H CB  1 
ATOM   11503 C CG  . ASP H 2 52  ? -9.522   -6.259  33.929  1.00 64.06  ? 52  ASP H CG  1 
ATOM   11504 O OD1 . ASP H 2 52  ? -9.341   -5.417  34.823  1.00 65.08  ? 52  ASP H OD1 1 
ATOM   11505 O OD2 . ASP H 2 52  ? -10.659  -6.639  33.568  1.00 73.68  ? 52  ASP H OD2 1 
ATOM   11506 N N   . GLY H 2 53  ? -4.874   -6.706  33.793  1.00 67.07  ? 53  GLY H N   1 
ATOM   11507 C CA  . GLY H 2 53  ? -3.634   -7.376  33.487  1.00 64.19  ? 53  GLY H CA  1 
ATOM   11508 C C   . GLY H 2 53  ? -2.431   -6.531  33.838  1.00 60.89  ? 53  GLY H C   1 
ATOM   11509 O O   . GLY H 2 53  ? -1.458   -7.035  34.413  1.00 55.70  ? 53  GLY H O   1 
ATOM   11510 N N   . ARG H 2 54  ? -2.480   -5.243  33.492  1.00 61.98  ? 54  ARG H N   1 
ATOM   11511 C CA  . ARG H 2 54  ? -1.383   -4.361  33.844  1.00 58.81  ? 54  ARG H CA  1 
ATOM   11512 C C   . ARG H 2 54  ? -1.479   -4.023  35.322  1.00 58.92  ? 54  ARG H C   1 
ATOM   11513 O O   . ARG H 2 54  ? -2.461   -4.343  35.993  1.00 62.43  ? 54  ARG H O   1 
ATOM   11514 C CB  . ARG H 2 54  ? -1.390   -3.104  32.982  1.00 54.09  ? 54  ARG H CB  1 
ATOM   11515 N N   . THR H 2 55  ? -0.442   -3.408  35.848  1.00 57.79  ? 55  THR H N   1 
ATOM   11516 C CA  . THR H 2 55  ? -0.482   -2.986  37.236  1.00 60.33  ? 55  THR H CA  1 
ATOM   11517 C C   . THR H 2 55  ? -0.621   -1.468  37.314  1.00 62.44  ? 55  THR H C   1 
ATOM   11518 O O   . THR H 2 55  ? -0.630   -0.761  36.306  1.00 63.57  ? 55  THR H O   1 
ATOM   11519 C CB  . THR H 2 55  ? 0.764    -3.462  37.965  1.00 61.90  ? 55  THR H CB  1 
ATOM   11520 O OG1 . THR H 2 55  ? 0.677    -3.070  39.338  1.00 69.60  ? 55  THR H OG1 1 
ATOM   11521 C CG2 . THR H 2 55  ? 1.972    -2.816  37.357  1.00 61.05  ? 55  THR H CG2 1 
ATOM   11522 N N   . LEU H 2 56  ? -0.741   -0.935  38.526  1.00 63.18  ? 56  LEU H N   1 
ATOM   11523 C CA  . LEU H 2 56  ? -0.886   0.533   38.714  1.00 63.38  ? 56  LEU H CA  1 
ATOM   11524 C C   . LEU H 2 56  ? 0.407    1.256   38.333  1.00 62.46  ? 56  LEU H C   1 
ATOM   11525 O O   . LEU H 2 56  ? 0.309    2.307   37.698  1.00 64.21  ? 56  LEU H O   1 
ATOM   11526 C CB  . LEU H 2 56  ? -1.212   0.804   40.181  1.00 61.42  ? 56  LEU H CB  1 
ATOM   11527 C CG  . LEU H 2 56  ? -2.567   1.424   40.490  1.00 53.97  ? 56  LEU H CG  1 
ATOM   11528 C CD1 . LEU H 2 56  ? -3.522   1.270   39.325  1.00 67.08  ? 56  LEU H CD1 1 
ATOM   11529 C CD2 . LEU H 2 56  ? -3.142   0.773   41.725  1.00 60.26  ? 56  LEU H CD2 1 
ATOM   11530 N N   . SER H 2 57  ? 1.563    0.731   38.746  1.00 59.88  ? 57  SER H N   1 
ATOM   11531 C CA  . SER H 2 57  ? 2.823    1.365   38.383  1.00 58.95  ? 57  SER H CA  1 
ATOM   11532 C C   . SER H 2 57  ? 2.996    1.445   36.874  1.00 59.30  ? 57  SER H C   1 
ATOM   11533 O O   . SER H 2 57  ? 3.645    2.371   36.380  1.00 64.94  ? 57  SER H O   1 
ATOM   11534 C CB  . SER H 2 57  ? 4.004    0.629   39.019  1.00 60.14  ? 57  SER H CB  1 
ATOM   11535 O OG  . SER H 2 57  ? 3.937    -0.772  38.816  1.00 64.98  ? 57  SER H OG  1 
ATOM   11536 N N   . ASP H 2 58  ? 2.401    0.514   36.127  1.00 62.52  ? 58  ASP H N   1 
ATOM   11537 C CA  . ASP H 2 58  ? 2.449    0.595   34.668  1.00 64.45  ? 58  ASP H CA  1 
ATOM   11538 C C   . ASP H 2 58  ? 1.827    1.881   34.138  1.00 60.82  ? 58  ASP H C   1 
ATOM   11539 O O   . ASP H 2 58  ? 2.077    2.239   32.984  1.00 71.28  ? 58  ASP H O   1 
ATOM   11540 C CB  . ASP H 2 58  ? 1.740    -0.602  34.006  1.00 58.81  ? 58  ASP H CB  1 
ATOM   11541 C CG  . ASP H 2 58  ? 2.461    -1.932  34.233  1.00 64.65  ? 58  ASP H CG  1 
ATOM   11542 O OD1 . ASP H 2 58  ? 3.595    -1.947  34.771  1.00 64.05  ? 58  ASP H OD1 1 
ATOM   11543 O OD2 . ASP H 2 58  ? 1.865    -2.977  33.888  1.00 64.68  ? 58  ASP H OD2 1 
ATOM   11544 N N   . TYR H 2 59  ? 1.054    2.584   34.955  1.00 56.50  ? 59  TYR H N   1 
ATOM   11545 C CA  . TYR H 2 59  ? 0.349    3.784   34.443  1.00 58.73  ? 59  TYR H CA  1 
ATOM   11546 C C   . TYR H 2 59  ? 0.857    5.037   35.159  1.00 58.25  ? 59  TYR H C   1 
ATOM   11547 O O   . TYR H 2 59  ? 0.277    6.103   34.931  1.00 55.94  ? 59  TYR H O   1 
ATOM   11548 C CB  . TYR H 2 59  ? -1.157   3.591   34.609  1.00 60.40  ? 59  TYR H CB  1 
ATOM   11549 C CG  . TYR H 2 59  ? -1.775   2.516   33.755  1.00 57.20  ? 59  TYR H CG  1 
ATOM   11550 C CD1 . TYR H 2 59  ? -1.889   2.673   32.385  1.00 58.11  ? 59  TYR H CD1 1 
ATOM   11551 C CD2 . TYR H 2 59  ? -2.267   1.353   34.318  1.00 59.08  ? 59  TYR H CD2 1 
ATOM   11552 C CE1 . TYR H 2 59  ? -2.466   1.696   31.594  1.00 58.82  ? 59  TYR H CE1 1 
ATOM   11553 C CE2 . TYR H 2 59  ? -2.845   0.364   33.541  1.00 57.92  ? 59  TYR H CE2 1 
ATOM   11554 C CZ  . TYR H 2 59  ? -2.946   0.538   32.174  1.00 60.60  ? 59  TYR H CZ  1 
ATOM   11555 O OH  . TYR H 2 59  ? -3.513   -0.426  31.396  1.00 64.65  ? 59  TYR H OH  1 
ATOM   11556 N N   . ASN H 2 60  ? 1.898    4.906   35.981  1.00 58.58  ? 60  ASN H N   1 
ATOM   11557 C CA  . ASN H 2 60  ? 2.464    6.034   36.775  1.00 63.67  ? 60  ASN H CA  1 
ATOM   11558 C C   . ASN H 2 60  ? 1.376    6.595   37.693  1.00 65.15  ? 60  ASN H C   1 
ATOM   11559 O O   . ASN H 2 60  ? 1.417    7.800   37.986  1.00 62.49  ? 60  ASN H O   1 
ATOM   11560 C CB  . ASN H 2 60  ? 3.178    7.072   35.905  1.00 58.52  ? 60  ASN H CB  1 
ATOM   11561 C CG  . ASN H 2 60  ? 4.651    6.779   35.734  1.00 69.99  ? 60  ASN H CG  1 
ATOM   11562 O OD1 . ASN H 2 60  ? 5.394    6.727   36.708  1.00 76.83  ? 60  ASN H OD1 1 
ATOM   11563 N ND2 . ASN H 2 60  ? 5.080    6.585   34.498  1.00 75.07  ? 60  ASN H ND2 1 
ATOM   11564 N N   . ILE H 2 61  ? 0.450    5.739   38.125  1.00 60.99  ? 61  ILE H N   1 
ATOM   11565 C CA  . ILE H 2 61  ? -0.614   6.151   39.078  1.00 53.21  ? 61  ILE H CA  1 
ATOM   11566 C C   . ILE H 2 61  ? 0.035    6.083   40.448  1.00 51.07  ? 61  ILE H C   1 
ATOM   11567 O O   . ILE H 2 61  ? 0.664    5.060   40.754  1.00 55.82  ? 61  ILE H O   1 
ATOM   11568 C CB  . ILE H 2 61  ? -1.853   5.245   38.951  1.00 46.27  ? 61  ILE H CB  1 
ATOM   11569 C CG1 . ILE H 2 61  ? -2.563   5.459   37.615  1.00 46.64  ? 61  ILE H CG1 1 
ATOM   11570 C CG2 . ILE H 2 61  ? -2.801   5.421   40.125  1.00 41.51  ? 61  ILE H CG2 1 
ATOM   11571 C CD1 . ILE H 2 61  ? -3.611   4.432   37.302  1.00 45.86  ? 61  ILE H CD1 1 
ATOM   11572 N N   . GLN H 2 62  ? -0.079   7.155   41.217  1.00 49.34  ? 62  GLN H N   1 
ATOM   11573 C CA  . GLN H 2 62  ? 0.605    7.180   42.480  1.00 50.08  ? 62  GLN H CA  1 
ATOM   11574 C C   . GLN H 2 62  ? -0.290   7.948   43.434  1.00 47.74  ? 62  GLN H C   1 
ATOM   11575 O O   . GLN H 2 62  ? -1.488   8.093   43.180  1.00 50.52  ? 62  GLN H O   1 
ATOM   11576 C CB  . GLN H 2 62  ? 2.009    7.780   42.305  1.00 54.55  ? 62  GLN H CB  1 
ATOM   11577 C CG  . GLN H 2 62  ? 1.961    9.159   41.707  1.00 54.39  ? 62  GLN H CG  1 
ATOM   11578 C CD  . GLN H 2 62  ? 3.299    9.650   41.236  1.00 68.34  ? 62  GLN H CD  1 
ATOM   11579 O OE1 . GLN H 2 62  ? 3.682    10.791  41.505  1.00 79.57  ? 62  GLN H OE1 1 
ATOM   11580 N NE2 . GLN H 2 62  ? 4.026    8.796   40.520  1.00 77.13  ? 62  GLN H NE2 1 
ATOM   11581 N N   . LYS H 2 63  ? 0.287    8.452   44.521  1.00 53.43  ? 63  LYS H N   1 
ATOM   11582 C CA  . LYS H 2 63  ? -0.516   9.098   45.548  1.00 54.09  ? 63  LYS H CA  1 
ATOM   11583 C C   . LYS H 2 63  ? -1.311   10.246  44.943  1.00 53.87  ? 63  LYS H C   1 
ATOM   11584 O O   . LYS H 2 63  ? -0.844   10.940  44.031  1.00 56.94  ? 63  LYS H O   1 
ATOM   11585 C CB  . LYS H 2 63  ? 0.368    9.601   46.700  1.00 54.60  ? 63  LYS H CB  1 
ATOM   11586 C CG  . LYS H 2 63  ? -0.378   9.667   48.041  1.00 51.33  ? 63  LYS H CG  1 
ATOM   11587 C CD  . LYS H 2 63  ? 0.102    10.789  48.935  1.00 45.70  ? 63  LYS H CD  1 
ATOM   11588 C CE  . LYS H 2 63  ? -0.684   10.844  50.249  1.00 49.16  ? 63  LYS H CE  1 
ATOM   11589 N NZ  . LYS H 2 63  ? -1.822   11.783  50.291  1.00 44.29  ? 63  LYS H NZ  1 
ATOM   11590 N N   . GLU H 2 64  ? -2.542   10.403  45.422  1.00 49.71  ? 64  GLU H N   1 
ATOM   11591 C CA  . GLU H 2 64  ? -3.440   11.502  45.078  1.00 53.09  ? 64  GLU H CA  1 
ATOM   11592 C C   . GLU H 2 64  ? -3.766   11.557  43.598  1.00 46.13  ? 64  GLU H C   1 
ATOM   11593 O O   . GLU H 2 64  ? -4.430   12.490  43.166  1.00 52.30  ? 64  GLU H O   1 
ATOM   11594 C CB  . GLU H 2 64  ? -2.888   12.851  45.563  1.00 45.31  ? 64  GLU H CB  1 
ATOM   11595 C CG  . GLU H 2 64  ? -2.585   12.846  47.054  1.00 49.30  ? 64  GLU H CG  1 
ATOM   11596 C CD  . GLU H 2 64  ? -1.726   14.019  47.484  1.00 59.31  ? 64  GLU H CD  1 
ATOM   11597 O OE1 . GLU H 2 64  ? -1.697   15.025  46.735  1.00 60.34  ? 64  GLU H OE1 1 
ATOM   11598 O OE2 . GLU H 2 64  ? -1.080   13.938  48.567  1.00 54.58  ? 64  GLU H OE2 1 
ATOM   11599 N N   . SER H 2 65  ? -3.327   10.574  42.815  1.00 42.83  ? 65  SER H N   1 
ATOM   11600 C CA  . SER H 2 65  ? -3.874   10.376  41.481  1.00 47.95  ? 65  SER H CA  1 
ATOM   11601 C C   . SER H 2 65  ? -5.392   10.284  41.529  1.00 44.83  ? 65  SER H C   1 
ATOM   11602 O O   . SER H 2 65  ? -5.961   9.787   42.502  1.00 49.54  ? 65  SER H O   1 
ATOM   11603 C CB  . SER H 2 65  ? -3.330   9.092   40.876  1.00 47.22  ? 65  SER H CB  1 
ATOM   11604 O OG  . SER H 2 65  ? -2.136   9.332   40.160  1.00 55.68  ? 65  SER H OG  1 
ATOM   11605 N N   . THR H 2 66  ? -6.061   10.751  40.468  1.00 40.01  ? 66  THR H N   1 
ATOM   11606 C CA  . THR H 2 66  ? -7.517   10.627  40.348  1.00 42.18  ? 66  THR H CA  1 
ATOM   11607 C C   . THR H 2 66  ? -7.885   9.729   39.171  1.00 43.38  ? 66  THR H C   1 
ATOM   11608 O O   . THR H 2 66  ? -7.603   10.064  38.017  1.00 45.72  ? 66  THR H O   1 
ATOM   11609 C CB  . THR H 2 66  ? -8.208   11.979  40.163  1.00 43.69  ? 66  THR H CB  1 
ATOM   11610 O OG1 . THR H 2 66  ? -8.058   12.794  41.330  1.00 48.88  ? 66  THR H OG1 1 
ATOM   11611 C CG2 . THR H 2 66  ? -9.691   11.741  39.922  1.00 50.37  ? 66  THR H CG2 1 
ATOM   11612 N N   . LEU H 2 67  ? -8.541   8.609   39.458  1.00 46.19  ? 67  LEU H N   1 
ATOM   11613 C CA  . LEU H 2 67  ? -9.088   7.734   38.426  1.00 47.16  ? 67  LEU H CA  1 
ATOM   11614 C C   . LEU H 2 67  ? -10.561  8.074   38.212  1.00 44.51  ? 67  LEU H C   1 
ATOM   11615 O O   . LEU H 2 67  ? -11.264  8.471   39.147  1.00 45.59  ? 67  LEU H O   1 
ATOM   11616 C CB  . LEU H 2 67  ? -8.950   6.255   38.818  1.00 45.20  ? 67  LEU H CB  1 
ATOM   11617 C CG  . LEU H 2 67  ? -7.603   5.511   38.759  1.00 45.02  ? 67  LEU H CG  1 
ATOM   11618 C CD1 . LEU H 2 67  ? -6.479   6.291   39.351  1.00 46.44  ? 67  LEU H CD1 1 
ATOM   11619 C CD2 . LEU H 2 67  ? -7.707   4.207   39.493  1.00 46.79  ? 67  LEU H CD2 1 
ATOM   11620 N N   . HIS H 2 68  ? -11.039  7.897   36.986  1.00 40.99  ? 68  HIS H N   1 
ATOM   11621 C CA  . HIS H 2 68  ? -12.406  8.292   36.640  1.00 50.79  ? 68  HIS H CA  1 
ATOM   11622 C C   . HIS H 2 68  ? -13.276  7.074   36.308  1.00 53.41  ? 68  HIS H C   1 
ATOM   11623 O O   . HIS H 2 68  ? -13.096  6.432   35.261  1.00 52.99  ? 68  HIS H O   1 
ATOM   11624 C CB  . HIS H 2 68  ? -12.380  9.309   35.501  1.00 49.20  ? 68  HIS H CB  1 
ATOM   11625 C CG  . HIS H 2 68  ? -11.608  10.548  35.846  1.00 55.86  ? 68  HIS H CG  1 
ATOM   11626 N ND1 . HIS H 2 68  ? -12.039  11.450  36.799  1.00 52.36  ? 68  HIS H ND1 1 
ATOM   11627 C CD2 . HIS H 2 68  ? -10.418  11.014  35.398  1.00 46.88  ? 68  HIS H CD2 1 
ATOM   11628 C CE1 . HIS H 2 68  ? -11.153  12.420  36.915  1.00 48.26  ? 68  HIS H CE1 1 
ATOM   11629 N NE2 . HIS H 2 68  ? -10.168  12.187  36.065  1.00 53.14  ? 68  HIS H NE2 1 
ATOM   11630 N N   . LEU H 2 69  ? -14.228  6.774   37.203  1.00 43.79  ? 69  LEU H N   1 
ATOM   11631 C CA  . LEU H 2 69  ? -15.105  5.625   37.034  1.00 52.07  ? 69  LEU H CA  1 
ATOM   11632 C C   . LEU H 2 69  ? -16.224  5.948   36.047  1.00 52.31  ? 69  LEU H C   1 
ATOM   11633 O O   . LEU H 2 69  ? -16.749  7.069   36.018  1.00 54.79  ? 69  LEU H O   1 
ATOM   11634 C CB  . LEU H 2 69  ? -15.683  5.179   38.382  1.00 53.07  ? 69  LEU H CB  1 
ATOM   11635 C CG  . LEU H 2 69  ? -16.454  3.841   38.389  1.00 59.01  ? 69  LEU H CG  1 
ATOM   11636 C CD1 . LEU H 2 69  ? -15.650  2.726   37.712  1.00 52.67  ? 69  LEU H CD1 1 
ATOM   11637 C CD2 . LEU H 2 69  ? -16.877  3.424   39.799  1.00 55.34  ? 69  LEU H CD2 1 
ATOM   11638 N N   . VAL H 2 70  ? -16.577  4.958   35.229  1.00 52.93  ? 70  VAL H N   1 
ATOM   11639 C CA  . VAL H 2 70  ? -17.430  5.148   34.058  1.00 54.21  ? 70  VAL H CA  1 
ATOM   11640 C C   . VAL H 2 70  ? -18.069  3.806   33.703  1.00 59.13  ? 70  VAL H C   1 
ATOM   11641 O O   . VAL H 2 70  ? -17.422  2.759   33.774  1.00 59.33  ? 70  VAL H O   1 
ATOM   11642 C CB  . VAL H 2 70  ? -16.611  5.720   32.877  1.00 50.88  ? 70  VAL H CB  1 
ATOM   11643 C CG1 . VAL H 2 70  ? -17.202  5.313   31.572  1.00 54.55  ? 70  VAL H CG1 1 
ATOM   11644 C CG2 . VAL H 2 70  ? -16.543  7.241   32.968  1.00 54.42  ? 70  VAL H CG2 1 
ATOM   11645 N N   . LEU H 2 71  ? -19.348  3.838   33.327  1.00 59.99  ? 71  LEU H N   1 
ATOM   11646 C CA  . LEU H 2 71  ? -20.037  2.633   32.889  1.00 58.05  ? 71  LEU H CA  1 
ATOM   11647 C C   . LEU H 2 71  ? -20.085  2.594   31.356  1.00 54.48  ? 71  LEU H C   1 
ATOM   11648 O O   . LEU H 2 71  ? -19.261  3.217   30.677  1.00 50.36  ? 71  LEU H O   1 
ATOM   11649 C CB  . LEU H 2 71  ? -21.442  2.553   33.526  1.00 59.59  ? 71  LEU H CB  1 
ATOM   11650 C CG  . LEU H 2 71  ? -21.591  2.256   35.032  1.00 55.86  ? 71  LEU H CG  1 
ATOM   11651 C CD1 . LEU H 2 71  ? -23.051  2.160   35.403  1.00 60.03  ? 71  LEU H CD1 1 
ATOM   11652 C CD2 . LEU H 2 71  ? -20.851  0.992   35.432  1.00 54.07  ? 71  LEU H CD2 1 
ATOM   11653 N N   . ARG H 2 72  ? -21.003  1.776   30.849  1.00 61.93  ? 72  ARG H N   1 
ATOM   11654 C CA  . ARG H 2 72  ? -21.093  1.566   29.390  1.00 61.89  ? 72  ARG H CA  1 
ATOM   11655 C C   . ARG H 2 72  ? -22.516  1.769   28.897  1.00 64.64  ? 72  ARG H C   1 
ATOM   11656 O O   . ARG H 2 72  ? -23.441  1.276   29.549  1.00 65.46  ? 72  ARG H O   1 
ATOM   11657 C CB  . ARG H 2 72  ? -20.755  0.114   29.054  1.00 53.54  ? 72  ARG H CB  1 
ATOM   11658 C CG  . ARG H 2 72  ? -19.305  -0.159  28.697  1.00 57.62  ? 72  ARG H CG  1 
ATOM   11659 C CD  . ARG H 2 72  ? -18.992  -1.589  29.078  1.00 59.34  ? 72  ARG H CD  1 
ATOM   11660 N NE  . ARG H 2 72  ? -17.647  -2.006  28.720  1.00 54.34  ? 72  ARG H NE  1 
ATOM   11661 C CZ  . ARG H 2 72  ? -16.817  -2.646  29.532  1.00 51.88  ? 72  ARG H CZ  1 
ATOM   11662 N NH1 . ARG H 2 72  ? -17.190  -2.946  30.763  1.00 46.69  ? 72  ARG H NH1 1 
ATOM   11663 N NH2 . ARG H 2 72  ? -15.613  -2.980  29.111  1.00 51.58  ? 72  ARG H NH2 1 
ATOM   11664 N N   . LEU H 2 73  ? -22.674  2.494   27.800  1.00 64.02  ? 73  LEU H N   1 
ATOM   11665 C CA  . LEU H 2 73  ? -23.993  2.616   27.140  1.00 66.26  ? 73  LEU H CA  1 
ATOM   11666 C C   . LEU H 2 73  ? -23.799  1.924   25.794  1.00 67.07  ? 73  LEU H C   1 
ATOM   11667 O O   . LEU H 2 73  ? -23.269  2.566   24.889  1.00 69.98  ? 73  LEU H O   1 
ATOM   11668 C CB  . LEU H 2 73  ? -24.371  4.090   26.994  1.00 63.54  ? 73  LEU H CB  1 
ATOM   11669 C CG  . LEU H 2 73  ? -25.053  4.715   28.207  1.00 61.81  ? 73  LEU H CG  1 
ATOM   11670 C CD1 . LEU H 2 73  ? -25.691  6.040   27.842  1.00 60.34  ? 73  LEU H CD1 1 
ATOM   11671 C CD2 . LEU H 2 73  ? -26.097  3.775   28.773  1.00 68.37  ? 73  LEU H CD2 1 
ATOM   11672 N N   . ARG H 2 74  ? -24.156  0.644   25.694  1.00 69.18  ? 74  ARG H N   1 
ATOM   11673 C CA  . ARG H 2 74  ? -23.880  -0.142  24.461  1.00 72.21  ? 74  ARG H CA  1 
ATOM   11674 C C   . ARG H 2 74  ? -24.932  0.111   23.379  1.00 67.03  ? 74  ARG H C   1 
ATOM   11675 O O   . ARG H 2 74  ? -26.064  0.443   23.731  1.00 63.87  ? 74  ARG H O   1 
ATOM   11676 C CB  . ARG H 2 74  ? -23.764  -1.620  24.834  1.00 70.15  ? 74  ARG H CB  1 
ATOM   11677 C CG  . ARG H 2 74  ? -22.624  -1.933  25.790  1.00 70.91  ? 74  ARG H CG  1 
ATOM   11678 C CD  . ARG H 2 74  ? -22.521  -3.429  26.001  1.00 71.72  ? 74  ARG H CD  1 
ATOM   11679 N NE  . ARG H 2 74  ? -21.469  -3.811  26.930  1.00 72.28  ? 74  ARG H NE  1 
ATOM   11680 C CZ  . ARG H 2 74  ? -20.318  -4.374  26.582  1.00 75.39  ? 74  ARG H CZ  1 
ATOM   11681 N NH1 . ARG H 2 74  ? -20.054  -4.622  25.311  1.00 67.77  ? 74  ARG H NH1 1 
ATOM   11682 N NH2 . ARG H 2 74  ? -19.433  -4.690  27.508  1.00 66.03  ? 74  ARG H NH2 1 
ATOM   11683 N N   . GLY H 2 75  ? -24.567  -0.079  22.109  1.00 64.66  ? 75  GLY H N   1 
ATOM   11684 C CA  . GLY H 2 75  ? -25.470  0.224   21.017  1.00 67.03  ? 75  GLY H CA  1 
ATOM   11685 C C   . GLY H 2 75  ? -25.168  -0.567  19.767  1.00 69.16  ? 75  GLY H C   1 
ATOM   11686 O O   . GLY H 2 75  ? -24.009  -0.888  19.508  1.00 72.97  ? 75  GLY H O   1 
HETATM 11687 C C10 . XB7 I 3 .   ? -75.090  -25.569 15.133  1.00 63.33  ? 601 XB7 C C10 1 
HETATM 11688 C C11 . XB7 I 3 .   ? -75.379  -24.408 14.228  1.00 72.45  ? 601 XB7 C C11 1 
HETATM 11689 C C12 . XB7 I 3 .   ? -74.849  -24.695 12.839  1.00 75.95  ? 601 XB7 C C12 1 
HETATM 11690 C C13 . XB7 I 3 .   ? -75.423  -24.775 17.597  1.00 66.28  ? 601 XB7 C C13 1 
HETATM 11691 C C14 . XB7 I 3 .   ? -74.449  -23.783 19.238  1.00 61.64  ? 601 XB7 C C14 1 
HETATM 11692 C C15 . XB7 I 3 .   ? -73.551  -23.205 20.116  1.00 62.02  ? 601 XB7 C C15 1 
HETATM 11693 C C16 . XB7 I 3 .   ? -74.049  -22.635 21.263  1.00 59.28  ? 601 XB7 C C16 1 
HETATM 11694 C C17 . XB7 I 3 .   ? -75.415  -22.636 21.546  1.00 60.63  ? 601 XB7 C C17 1 
HETATM 11695 C C18 . XB7 I 3 .   ? -76.324  -23.205 20.684  1.00 57.95  ? 601 XB7 C C18 1 
HETATM 11696 C C19 . XB7 I 3 .   ? -75.811  -23.777 19.535  1.00 63.25  ? 601 XB7 C C19 1 
HETATM 11697 C C20 . XB7 I 3 .   ? -77.853  -24.672 18.313  1.00 63.89  ? 601 XB7 C C20 1 
HETATM 11698 C C21 . XB7 I 3 .   ? -78.606  -23.551 17.643  1.00 64.30  ? 601 XB7 C C21 1 
HETATM 11699 C C22 . XB7 I 3 .   ? -78.727  -22.320 18.250  1.00 58.71  ? 601 XB7 C C22 1 
HETATM 11700 C C23 . XB7 I 3 .   ? -79.428  -21.289 17.650  1.00 55.66  ? 601 XB7 C C23 1 
HETATM 11701 C C24 . XB7 I 3 .   ? -80.007  -21.526 16.442  1.00 64.79  ? 601 XB7 C C24 1 
HETATM 11702 C C25 . XB7 I 3 .   ? -79.922  -22.727 15.805  1.00 60.87  ? 601 XB7 C C25 1 
HETATM 11703 C C26 . XB7 I 3 .   ? -79.212  -23.744 16.420  1.00 60.63  ? 601 XB7 C C26 1 
HETATM 11704 C C8  . XB7 I 3 .   ? -73.119  -26.131 13.751  1.00 71.84  ? 601 XB7 C C8  1 
HETATM 11705 C C9  . XB7 I 3 .   ? -73.622  -25.884 15.158  1.00 55.06  ? 601 XB7 C C9  1 
HETATM 11706 F F1  . XB7 I 3 .   ? -80.699  -20.519 15.846  1.00 63.49  ? 601 XB7 C F1  1 
HETATM 11707 N N1  . XB7 I 3 .   ? -73.414  -24.994 12.872  1.00 73.65  ? 601 XB7 C N1  1 
HETATM 11708 N N2  . XB7 I 3 .   ? -75.728  -25.470 16.443  1.00 67.84  ? 601 XB7 C N2  1 
HETATM 11709 N N3  . XB7 I 3 .   ? -74.225  -24.421 18.019  1.00 64.47  ? 601 XB7 C N3  1 
HETATM 11710 N N4  . XB7 I 3 .   ? -76.425  -24.417 18.469  1.00 64.85  ? 601 XB7 C N4  1 
HETATM 11711 O O   . HOH J 4 .   ? -28.235  -16.484 6.104   1.00 46.76  ? 601 HOH A O   1 
HETATM 11712 O O   . HOH J 4 .   ? -33.443  -36.667 -5.122  1.00 41.00  ? 602 HOH A O   1 
HETATM 11713 O O   . HOH J 4 .   ? -10.800  -18.430 25.244  1.00 44.67  ? 603 HOH A O   1 
HETATM 11714 O O   . HOH J 4 .   ? -33.394  -19.487 40.655  1.00 46.74  ? 604 HOH A O   1 
HETATM 11715 O O   . HOH J 4 .   ? -50.213  -24.362 31.014  1.00 43.91  ? 605 HOH A O   1 
HETATM 11716 O O   . HOH J 4 .   ? -51.326  -23.738 33.277  1.00 54.64  ? 606 HOH A O   1 
HETATM 11717 O O   . HOH J 4 .   ? -28.746  -33.825 57.165  1.00 58.62  ? 607 HOH A O   1 
HETATM 11718 O O   . HOH J 4 .   ? -30.285  -36.854 57.155  1.00 68.20  ? 608 HOH A O   1 
HETATM 11719 O O   . HOH J 4 .   ? -40.156  -48.647 28.089  1.00 55.22  ? 609 HOH A O   1 
HETATM 11720 O O   . HOH J 4 .   ? -40.885  -46.284 28.881  1.00 54.86  ? 610 HOH A O   1 
HETATM 11721 O O   . HOH K 4 .   ? -26.085  -46.676 15.659  1.00 42.77  ? 101 HOH B O   1 
HETATM 11722 O O   . HOH K 4 .   ? -46.993  -39.175 22.814  1.00 54.24  ? 102 HOH B O   1 
HETATM 11723 O O   . HOH L 4 .   ? -58.292  4.495   15.055  1.00 46.82  ? 701 HOH C O   1 
HETATM 11724 O O   . HOH L 4 .   ? -89.077  -18.378 7.513   1.00 55.08  ? 702 HOH C O   1 
HETATM 11725 O O   . HOH L 4 .   ? -74.038  -30.074 33.536  1.00 63.83  ? 703 HOH C O   1 
HETATM 11726 O O   . HOH L 4 .   ? -84.540  -4.994  3.928   1.00 56.62  ? 704 HOH C O   1 
HETATM 11727 O O   . HOH L 4 .   ? -85.031  0.980   14.732  1.00 56.59  ? 705 HOH C O   1 
HETATM 11728 O O   . HOH L 4 .   ? -73.322  -4.219  4.455   1.00 51.11  ? 706 HOH C O   1 
HETATM 11729 O O   . HOH L 4 .   ? -56.141  5.388   21.729  1.00 49.54  ? 707 HOH C O   1 
HETATM 11730 O O   . HOH L 4 .   ? -77.197  -1.881  8.666   1.00 43.62  ? 708 HOH C O   1 
HETATM 11731 O O   . HOH L 4 .   ? -60.903  -1.387  0.337   1.00 46.25  ? 709 HOH C O   1 
HETATM 11732 O O   . HOH L 4 .   ? -92.886  4.270   22.025  1.00 52.65  ? 710 HOH C O   1 
HETATM 11733 O O   . HOH L 4 .   ? -57.565  7.116   18.269  1.00 43.98  ? 711 HOH C O   1 
HETATM 11734 O O   . HOH L 4 .   ? -95.316  -6.767  42.571  1.00 43.30  ? 712 HOH C O   1 
HETATM 11735 O O   . HOH L 4 .   ? -53.628  4.623   11.230  1.00 40.49  ? 713 HOH C O   1 
HETATM 11736 O O   . HOH L 4 .   ? -92.392  -27.123 27.471  1.00 65.25  ? 714 HOH C O   1 
HETATM 11737 O O   . HOH M 4 .   ? -64.651  -24.941 26.011  1.00 39.31  ? 101 HOH D O   1 
HETATM 11738 O O   . HOH M 4 .   ? -62.918  -26.929 16.904  1.00 57.62  ? 102 HOH D O   1 
HETATM 11739 O O   . HOH M 4 .   ? -52.560  -26.377 18.923  1.00 45.29  ? 103 HOH D O   1 
HETATM 11740 O O   . HOH N 4 .   ? -61.662  47.959  46.081  1.00 57.08  ? 601 HOH E O   1 
HETATM 11741 O O   . HOH N 4 .   ? -101.413 25.615  36.086  1.00 53.03  ? 602 HOH E O   1 
HETATM 11742 O O   . HOH N 4 .   ? -64.295  40.629  50.231  1.00 55.33  ? 603 HOH E O   1 
HETATM 11743 O O   . HOH O 4 .   ? -80.260  16.052  32.783  1.00 31.40  ? 101 HOH F O   1 
HETATM 11744 O O   . HOH P 4 .   ? -13.971  -7.884  10.864  1.00 69.78  ? 601 HOH G O   1 
HETATM 11745 O O   . HOH P 4 .   ? -9.164   28.125  24.534  1.00 51.13  ? 602 HOH G O   1 
HETATM 11746 O O   . HOH P 4 .   ? -31.168  21.112  24.394  1.00 61.50  ? 603 HOH G O   1 
HETATM 11747 O O   . HOH P 4 .   ? -36.971  18.567  17.863  1.00 59.24  ? 604 HOH G O   1 
HETATM 11748 O O   . HOH P 4 .   ? -16.080  -4.247  2.767   1.00 62.29  ? 605 HOH G O   1 
HETATM 11749 O O   . HOH Q 4 .   ? -8.164   -9.737  41.811  1.00 57.54  ? 101 HOH H O   1 
HETATM 11750 O O   . HOH Q 4 .   ? -12.986  -7.474  35.038  1.00 59.04  ? 102 HOH H O   1 
HETATM 11751 O O   . HOH Q 4 .   ? -21.303  -4.379  30.729  1.00 37.06  ? 103 HOH H O   1 
# 
