data_9IK4
# 
_entry.id   9IK4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9IK4         pdb_00009ik4 10.2210/pdb9ik4/pdb 
WWPDB D_1300048982 ?            ?                   
EMDB  EMD-60648    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1  'Structure model' 1 0 2025-01-22 ? 
2  'EM metadata'     1 0 2025-01-22 ? 
3  'Additional map'  1 0 2025-01-22 ? 
4  FSC               1 0 2025-01-22 ? 
5  'Half map'        1 0 2025-01-22 1 
6  'Half map'        1 0 2025-01-22 2 
7  Image             1 0 2025-01-22 ? 
8  'Primary map'     1 0 2025-01-22 ? 
9  'Structure model' 1 1 2025-01-29 ? 
10 'Additional map'  1 0 2025-01-22 ? 
11 FSC               1 0 2025-01-22 ? 
12 'Half map'        1 0 2025-01-22 1 
13 'Half map'        1 0 2025-01-22 2 
14 Image             1 0 2025-01-22 ? 
15 'Primary map'     1 0 2025-01-22 ? 
16 'Structure model' 1 2 2025-03-05 ? 
17 'EM metadata'     1 1 2025-03-05 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1  1  'Structure model' repository 'Initial release' ? ? 
2  2  'EM metadata'     repository 'Initial release' ? ? 
3  3  'Additional map'  repository 'Initial release' ? ? 
4  4  FSC               repository 'Initial release' ? ? 
5  5  'Half map'        repository 'Initial release' ? ? 
6  6  'Half map'        repository 'Initial release' ? ? 
7  7  Image             repository 'Initial release' ? ? 
8  8  'Primary map'     repository 'Initial release' ? ? 
9  10 'Additional map'  repository 'Initial release' ? ? 
10 11 FSC               repository 'Initial release' ? ? 
11 12 'Half map'        repository 'Initial release' ? ? 
12 13 'Half map'        repository 'Initial release' ? ? 
13 14 Image             repository 'Initial release' ? ? 
14 15 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 9  'Structure model' 'Data collection'      
2 9  'Structure model' 'Database references'  
3 16 'Structure model' 'Data collection'      
4 16 'Structure model' 'Database references'  
5 17 'EM metadata'     'Database references'  
6 17 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 9  'Structure model' citation        
2 9  'Structure model' citation_author 
3 9  'Structure model' em_admin        
4 16 'Structure model' citation        
5 16 'Structure model' citation_author 
6 16 'Structure model' em_admin        
7 17 'EM metadata'     citation        
8 17 'EM metadata'     citation_author 
9 17 'EM metadata'     em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  9  'Structure model' '_citation.country'                 
2  9  'Structure model' '_citation.journal_abbrev'          
3  9  'Structure model' '_citation.journal_id_CSD'          
4  9  'Structure model' '_citation.journal_id_ISSN'         
5  9  'Structure model' '_citation.pdbx_database_id_DOI'    
6  9  'Structure model' '_citation.pdbx_database_id_PubMed' 
7  9  'Structure model' '_citation.title'                   
8  9  'Structure model' '_citation.year'                    
9  9  'Structure model' '_em_admin.last_update'             
10 16 'Structure model' '_citation.journal_volume'          
11 16 'Structure model' '_citation.page_first'              
12 16 'Structure model' '_citation.page_last'               
13 16 'Structure model' '_citation_author.identifier_ORCID' 
14 16 'Structure model' '_em_admin.last_update'             
15 17 'EM metadata'     '_citation.journal_volume'          
16 17 'EM metadata'     '_citation.page_first'              
17 17 'EM metadata'     '_citation.page_last'               
18 17 'EM metadata'     '_citation_author.identifier_ORCID' 
19 17 'EM metadata'     '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9IK4 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Arabidopsis thaliana phosphate transporter PHO1;H1' 
_pdbx_database_related.db_id          EMD-60648 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              pengzhang01@cemps.ac.cn 
_pdbx_contact_author.name_first         Peng 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0408-2923 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Fang, S.'  1 0000-0002-8917-778X 
'Zhang, X.' 2 0000-0003-3138-6295 
'Zhang, P.' 3 0000-0003-0408-2923 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nat.Plants 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2055-0278 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            11 
_citation.language                  ? 
_citation.page_first                309 
_citation.page_last                 320 
_citation.title                     'Structural mechanism underlying PHO1;H1-mediated phosphate transport in Arabidopsis.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41477-024-01895-6 
_citation.pdbx_database_id_PubMed   39838070 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fang, S.'   1  ? 
primary 'Yang, Y.'   2  ? 
primary 'Zhang, X.'  3  ? 
primary 'Yang, Z.'   4  ? 
primary 'Zhang, M.'  5  ? 
primary 'Zhao, Y.'   6  ? 
primary 'Zhang, C.'  7  ? 
primary 'Yu, F.'     8  ? 
primary 'Wang, Y.F.' 9  ? 
primary 'Zhang, P.'  10 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Phosphate transporter PHO1 homolog 1' 89402.562 2 ? ? ? ? 
2 non-polymer syn 'INOSITOL HEXAKISPHOSPHATE'            660.035   2 ? ? ? ? 
3 non-polymer syn 'PHOSPHATE ION'                        94.971    2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Protein PHO1 homolog 1,AtPHO1;H1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MVKFTKQFEGQLVPEWKDAFVDYSQLKKDLKKIHLFTNGVEKKHTETSLIKTVKSSLGRLSIFGNKGREQSRVIQVHKKL
ASSGSNNDVYETELLEKIADDTDAAKEFFACLDMQLNKVNQFYKTKEKEFLERGECLKKQMDILIELKDAFKQKQANGES
TQESKEDDSISCTISCEYDSVRGRTEEMQLQVSCLDNLEDNGEEALESLGSEEPIKANNEDSKLTTVSSRVFSCQGKNVK
IKIPLTNPSRTFSAISYLINQSSSKKNGPDGGNKLQISKKKLSHAEKMIKGALTELFKGLNYLKTYRNLNILAFMNILKK
FDKVTGKQILPIYLKVVESSYFNISDKVMILSDEVEEWFIKHLAGENRRKAMKYLKPHHRKESHSVTFFIGLFTGCFVAL
LAGYIIVAHLTGMYRQHSANTFYMETAYPVLSMFGLLFLHLFLYGCNIFMWRKARINYSFIFELGSKNELKYRDVFLICT
ASMSAIAGVMFVHLSLLEKGYSFRQVQVIPGLLLLGFLLILICPLNIFYKSSRYRLISVIRNIVFSPLYKVVMLDFFMAD
QLCSQVPMLRNLEYIACYYITGSYATQDYEYCMRVKYYRDLAYAVSFLPYYWRAMQCARRWFDEGETSHLVNLGKYVSAM
LAAGTKVAYEKERSLGWLCLVVAMSSVATIYQLYWDFVKDWGLLQHNSNNPWLRNQLMLRQKSIYYFSMVLNLVLRLAWL
QTVLHSSFEHVDYRVTGLFLAALEVIRRGQWNFYRLENEHLNNAGKFRAVKT
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MVKFTKQFEGQLVPEWKDAFVDYSQLKKDLKKIHLFTNGVEKKHTETSLIKTVKSSLGRLSIFGNKGREQSRVIQVHKKL
ASSGSNNDVYETELLEKIADDTDAAKEFFACLDMQLNKVNQFYKTKEKEFLERGECLKKQMDILIELKDAFKQKQANGES
TQESKEDDSISCTISCEYDSVRGRTEEMQLQVSCLDNLEDNGEEALESLGSEEPIKANNEDSKLTTVSSRVFSCQGKNVK
IKIPLTNPSRTFSAISYLINQSSSKKNGPDGGNKLQISKKKLSHAEKMIKGALTELFKGLNYLKTYRNLNILAFMNILKK
FDKVTGKQILPIYLKVVESSYFNISDKVMILSDEVEEWFIKHLAGENRRKAMKYLKPHHRKESHSVTFFIGLFTGCFVAL
LAGYIIVAHLTGMYRQHSANTFYMETAYPVLSMFGLLFLHLFLYGCNIFMWRKARINYSFIFELGSKNELKYRDVFLICT
ASMSAIAGVMFVHLSLLEKGYSFRQVQVIPGLLLLGFLLILICPLNIFYKSSRYRLISVIRNIVFSPLYKVVMLDFFMAD
QLCSQVPMLRNLEYIACYYITGSYATQDYEYCMRVKYYRDLAYAVSFLPYYWRAMQCARRWFDEGETSHLVNLGKYVSAM
LAAGTKVAYEKERSLGWLCLVVAMSSVATIYQLYWDFVKDWGLLQHNSNNPWLRNQLMLRQKSIYYFSMVLNLVLRLAWL
QTVLHSSFEHVDYRVTGLFLAALEVIRRGQWNFYRLENEHLNNAGKFRAVKT
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'INOSITOL HEXAKISPHOSPHATE' IHP 
3 'PHOSPHATE ION'             PO4 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   VAL n 
1 3   LYS n 
1 4   PHE n 
1 5   THR n 
1 6   LYS n 
1 7   GLN n 
1 8   PHE n 
1 9   GLU n 
1 10  GLY n 
1 11  GLN n 
1 12  LEU n 
1 13  VAL n 
1 14  PRO n 
1 15  GLU n 
1 16  TRP n 
1 17  LYS n 
1 18  ASP n 
1 19  ALA n 
1 20  PHE n 
1 21  VAL n 
1 22  ASP n 
1 23  TYR n 
1 24  SER n 
1 25  GLN n 
1 26  LEU n 
1 27  LYS n 
1 28  LYS n 
1 29  ASP n 
1 30  LEU n 
1 31  LYS n 
1 32  LYS n 
1 33  ILE n 
1 34  HIS n 
1 35  LEU n 
1 36  PHE n 
1 37  THR n 
1 38  ASN n 
1 39  GLY n 
1 40  VAL n 
1 41  GLU n 
1 42  LYS n 
1 43  LYS n 
1 44  HIS n 
1 45  THR n 
1 46  GLU n 
1 47  THR n 
1 48  SER n 
1 49  LEU n 
1 50  ILE n 
1 51  LYS n 
1 52  THR n 
1 53  VAL n 
1 54  LYS n 
1 55  SER n 
1 56  SER n 
1 57  LEU n 
1 58  GLY n 
1 59  ARG n 
1 60  LEU n 
1 61  SER n 
1 62  ILE n 
1 63  PHE n 
1 64  GLY n 
1 65  ASN n 
1 66  LYS n 
1 67  GLY n 
1 68  ARG n 
1 69  GLU n 
1 70  GLN n 
1 71  SER n 
1 72  ARG n 
1 73  VAL n 
1 74  ILE n 
1 75  GLN n 
1 76  VAL n 
1 77  HIS n 
1 78  LYS n 
1 79  LYS n 
1 80  LEU n 
1 81  ALA n 
1 82  SER n 
1 83  SER n 
1 84  GLY n 
1 85  SER n 
1 86  ASN n 
1 87  ASN n 
1 88  ASP n 
1 89  VAL n 
1 90  TYR n 
1 91  GLU n 
1 92  THR n 
1 93  GLU n 
1 94  LEU n 
1 95  LEU n 
1 96  GLU n 
1 97  LYS n 
1 98  ILE n 
1 99  ALA n 
1 100 ASP n 
1 101 ASP n 
1 102 THR n 
1 103 ASP n 
1 104 ALA n 
1 105 ALA n 
1 106 LYS n 
1 107 GLU n 
1 108 PHE n 
1 109 PHE n 
1 110 ALA n 
1 111 CYS n 
1 112 LEU n 
1 113 ASP n 
1 114 MET n 
1 115 GLN n 
1 116 LEU n 
1 117 ASN n 
1 118 LYS n 
1 119 VAL n 
1 120 ASN n 
1 121 GLN n 
1 122 PHE n 
1 123 TYR n 
1 124 LYS n 
1 125 THR n 
1 126 LYS n 
1 127 GLU n 
1 128 LYS n 
1 129 GLU n 
1 130 PHE n 
1 131 LEU n 
1 132 GLU n 
1 133 ARG n 
1 134 GLY n 
1 135 GLU n 
1 136 CYS n 
1 137 LEU n 
1 138 LYS n 
1 139 LYS n 
1 140 GLN n 
1 141 MET n 
1 142 ASP n 
1 143 ILE n 
1 144 LEU n 
1 145 ILE n 
1 146 GLU n 
1 147 LEU n 
1 148 LYS n 
1 149 ASP n 
1 150 ALA n 
1 151 PHE n 
1 152 LYS n 
1 153 GLN n 
1 154 LYS n 
1 155 GLN n 
1 156 ALA n 
1 157 ASN n 
1 158 GLY n 
1 159 GLU n 
1 160 SER n 
1 161 THR n 
1 162 GLN n 
1 163 GLU n 
1 164 SER n 
1 165 LYS n 
1 166 GLU n 
1 167 ASP n 
1 168 ASP n 
1 169 SER n 
1 170 ILE n 
1 171 SER n 
1 172 CYS n 
1 173 THR n 
1 174 ILE n 
1 175 SER n 
1 176 CYS n 
1 177 GLU n 
1 178 TYR n 
1 179 ASP n 
1 180 SER n 
1 181 VAL n 
1 182 ARG n 
1 183 GLY n 
1 184 ARG n 
1 185 THR n 
1 186 GLU n 
1 187 GLU n 
1 188 MET n 
1 189 GLN n 
1 190 LEU n 
1 191 GLN n 
1 192 VAL n 
1 193 SER n 
1 194 CYS n 
1 195 LEU n 
1 196 ASP n 
1 197 ASN n 
1 198 LEU n 
1 199 GLU n 
1 200 ASP n 
1 201 ASN n 
1 202 GLY n 
1 203 GLU n 
1 204 GLU n 
1 205 ALA n 
1 206 LEU n 
1 207 GLU n 
1 208 SER n 
1 209 LEU n 
1 210 GLY n 
1 211 SER n 
1 212 GLU n 
1 213 GLU n 
1 214 PRO n 
1 215 ILE n 
1 216 LYS n 
1 217 ALA n 
1 218 ASN n 
1 219 ASN n 
1 220 GLU n 
1 221 ASP n 
1 222 SER n 
1 223 LYS n 
1 224 LEU n 
1 225 THR n 
1 226 THR n 
1 227 VAL n 
1 228 SER n 
1 229 SER n 
1 230 ARG n 
1 231 VAL n 
1 232 PHE n 
1 233 SER n 
1 234 CYS n 
1 235 GLN n 
1 236 GLY n 
1 237 LYS n 
1 238 ASN n 
1 239 VAL n 
1 240 LYS n 
1 241 ILE n 
1 242 LYS n 
1 243 ILE n 
1 244 PRO n 
1 245 LEU n 
1 246 THR n 
1 247 ASN n 
1 248 PRO n 
1 249 SER n 
1 250 ARG n 
1 251 THR n 
1 252 PHE n 
1 253 SER n 
1 254 ALA n 
1 255 ILE n 
1 256 SER n 
1 257 TYR n 
1 258 LEU n 
1 259 ILE n 
1 260 ASN n 
1 261 GLN n 
1 262 SER n 
1 263 SER n 
1 264 SER n 
1 265 LYS n 
1 266 LYS n 
1 267 ASN n 
1 268 GLY n 
1 269 PRO n 
1 270 ASP n 
1 271 GLY n 
1 272 GLY n 
1 273 ASN n 
1 274 LYS n 
1 275 LEU n 
1 276 GLN n 
1 277 ILE n 
1 278 SER n 
1 279 LYS n 
1 280 LYS n 
1 281 LYS n 
1 282 LEU n 
1 283 SER n 
1 284 HIS n 
1 285 ALA n 
1 286 GLU n 
1 287 LYS n 
1 288 MET n 
1 289 ILE n 
1 290 LYS n 
1 291 GLY n 
1 292 ALA n 
1 293 LEU n 
1 294 THR n 
1 295 GLU n 
1 296 LEU n 
1 297 PHE n 
1 298 LYS n 
1 299 GLY n 
1 300 LEU n 
1 301 ASN n 
1 302 TYR n 
1 303 LEU n 
1 304 LYS n 
1 305 THR n 
1 306 TYR n 
1 307 ARG n 
1 308 ASN n 
1 309 LEU n 
1 310 ASN n 
1 311 ILE n 
1 312 LEU n 
1 313 ALA n 
1 314 PHE n 
1 315 MET n 
1 316 ASN n 
1 317 ILE n 
1 318 LEU n 
1 319 LYS n 
1 320 LYS n 
1 321 PHE n 
1 322 ASP n 
1 323 LYS n 
1 324 VAL n 
1 325 THR n 
1 326 GLY n 
1 327 LYS n 
1 328 GLN n 
1 329 ILE n 
1 330 LEU n 
1 331 PRO n 
1 332 ILE n 
1 333 TYR n 
1 334 LEU n 
1 335 LYS n 
1 336 VAL n 
1 337 VAL n 
1 338 GLU n 
1 339 SER n 
1 340 SER n 
1 341 TYR n 
1 342 PHE n 
1 343 ASN n 
1 344 ILE n 
1 345 SER n 
1 346 ASP n 
1 347 LYS n 
1 348 VAL n 
1 349 MET n 
1 350 ILE n 
1 351 LEU n 
1 352 SER n 
1 353 ASP n 
1 354 GLU n 
1 355 VAL n 
1 356 GLU n 
1 357 GLU n 
1 358 TRP n 
1 359 PHE n 
1 360 ILE n 
1 361 LYS n 
1 362 HIS n 
1 363 LEU n 
1 364 ALA n 
1 365 GLY n 
1 366 GLU n 
1 367 ASN n 
1 368 ARG n 
1 369 ARG n 
1 370 LYS n 
1 371 ALA n 
1 372 MET n 
1 373 LYS n 
1 374 TYR n 
1 375 LEU n 
1 376 LYS n 
1 377 PRO n 
1 378 HIS n 
1 379 HIS n 
1 380 ARG n 
1 381 LYS n 
1 382 GLU n 
1 383 SER n 
1 384 HIS n 
1 385 SER n 
1 386 VAL n 
1 387 THR n 
1 388 PHE n 
1 389 PHE n 
1 390 ILE n 
1 391 GLY n 
1 392 LEU n 
1 393 PHE n 
1 394 THR n 
1 395 GLY n 
1 396 CYS n 
1 397 PHE n 
1 398 VAL n 
1 399 ALA n 
1 400 LEU n 
1 401 LEU n 
1 402 ALA n 
1 403 GLY n 
1 404 TYR n 
1 405 ILE n 
1 406 ILE n 
1 407 VAL n 
1 408 ALA n 
1 409 HIS n 
1 410 LEU n 
1 411 THR n 
1 412 GLY n 
1 413 MET n 
1 414 TYR n 
1 415 ARG n 
1 416 GLN n 
1 417 HIS n 
1 418 SER n 
1 419 ALA n 
1 420 ASN n 
1 421 THR n 
1 422 PHE n 
1 423 TYR n 
1 424 MET n 
1 425 GLU n 
1 426 THR n 
1 427 ALA n 
1 428 TYR n 
1 429 PRO n 
1 430 VAL n 
1 431 LEU n 
1 432 SER n 
1 433 MET n 
1 434 PHE n 
1 435 GLY n 
1 436 LEU n 
1 437 LEU n 
1 438 PHE n 
1 439 LEU n 
1 440 HIS n 
1 441 LEU n 
1 442 PHE n 
1 443 LEU n 
1 444 TYR n 
1 445 GLY n 
1 446 CYS n 
1 447 ASN n 
1 448 ILE n 
1 449 PHE n 
1 450 MET n 
1 451 TRP n 
1 452 ARG n 
1 453 LYS n 
1 454 ALA n 
1 455 ARG n 
1 456 ILE n 
1 457 ASN n 
1 458 TYR n 
1 459 SER n 
1 460 PHE n 
1 461 ILE n 
1 462 PHE n 
1 463 GLU n 
1 464 LEU n 
1 465 GLY n 
1 466 SER n 
1 467 LYS n 
1 468 ASN n 
1 469 GLU n 
1 470 LEU n 
1 471 LYS n 
1 472 TYR n 
1 473 ARG n 
1 474 ASP n 
1 475 VAL n 
1 476 PHE n 
1 477 LEU n 
1 478 ILE n 
1 479 CYS n 
1 480 THR n 
1 481 ALA n 
1 482 SER n 
1 483 MET n 
1 484 SER n 
1 485 ALA n 
1 486 ILE n 
1 487 ALA n 
1 488 GLY n 
1 489 VAL n 
1 490 MET n 
1 491 PHE n 
1 492 VAL n 
1 493 HIS n 
1 494 LEU n 
1 495 SER n 
1 496 LEU n 
1 497 LEU n 
1 498 GLU n 
1 499 LYS n 
1 500 GLY n 
1 501 TYR n 
1 502 SER n 
1 503 PHE n 
1 504 ARG n 
1 505 GLN n 
1 506 VAL n 
1 507 GLN n 
1 508 VAL n 
1 509 ILE n 
1 510 PRO n 
1 511 GLY n 
1 512 LEU n 
1 513 LEU n 
1 514 LEU n 
1 515 LEU n 
1 516 GLY n 
1 517 PHE n 
1 518 LEU n 
1 519 LEU n 
1 520 ILE n 
1 521 LEU n 
1 522 ILE n 
1 523 CYS n 
1 524 PRO n 
1 525 LEU n 
1 526 ASN n 
1 527 ILE n 
1 528 PHE n 
1 529 TYR n 
1 530 LYS n 
1 531 SER n 
1 532 SER n 
1 533 ARG n 
1 534 TYR n 
1 535 ARG n 
1 536 LEU n 
1 537 ILE n 
1 538 SER n 
1 539 VAL n 
1 540 ILE n 
1 541 ARG n 
1 542 ASN n 
1 543 ILE n 
1 544 VAL n 
1 545 PHE n 
1 546 SER n 
1 547 PRO n 
1 548 LEU n 
1 549 TYR n 
1 550 LYS n 
1 551 VAL n 
1 552 VAL n 
1 553 MET n 
1 554 LEU n 
1 555 ASP n 
1 556 PHE n 
1 557 PHE n 
1 558 MET n 
1 559 ALA n 
1 560 ASP n 
1 561 GLN n 
1 562 LEU n 
1 563 CYS n 
1 564 SER n 
1 565 GLN n 
1 566 VAL n 
1 567 PRO n 
1 568 MET n 
1 569 LEU n 
1 570 ARG n 
1 571 ASN n 
1 572 LEU n 
1 573 GLU n 
1 574 TYR n 
1 575 ILE n 
1 576 ALA n 
1 577 CYS n 
1 578 TYR n 
1 579 TYR n 
1 580 ILE n 
1 581 THR n 
1 582 GLY n 
1 583 SER n 
1 584 TYR n 
1 585 ALA n 
1 586 THR n 
1 587 GLN n 
1 588 ASP n 
1 589 TYR n 
1 590 GLU n 
1 591 TYR n 
1 592 CYS n 
1 593 MET n 
1 594 ARG n 
1 595 VAL n 
1 596 LYS n 
1 597 TYR n 
1 598 TYR n 
1 599 ARG n 
1 600 ASP n 
1 601 LEU n 
1 602 ALA n 
1 603 TYR n 
1 604 ALA n 
1 605 VAL n 
1 606 SER n 
1 607 PHE n 
1 608 LEU n 
1 609 PRO n 
1 610 TYR n 
1 611 TYR n 
1 612 TRP n 
1 613 ARG n 
1 614 ALA n 
1 615 MET n 
1 616 GLN n 
1 617 CYS n 
1 618 ALA n 
1 619 ARG n 
1 620 ARG n 
1 621 TRP n 
1 622 PHE n 
1 623 ASP n 
1 624 GLU n 
1 625 GLY n 
1 626 GLU n 
1 627 THR n 
1 628 SER n 
1 629 HIS n 
1 630 LEU n 
1 631 VAL n 
1 632 ASN n 
1 633 LEU n 
1 634 GLY n 
1 635 LYS n 
1 636 TYR n 
1 637 VAL n 
1 638 SER n 
1 639 ALA n 
1 640 MET n 
1 641 LEU n 
1 642 ALA n 
1 643 ALA n 
1 644 GLY n 
1 645 THR n 
1 646 LYS n 
1 647 VAL n 
1 648 ALA n 
1 649 TYR n 
1 650 GLU n 
1 651 LYS n 
1 652 GLU n 
1 653 ARG n 
1 654 SER n 
1 655 LEU n 
1 656 GLY n 
1 657 TRP n 
1 658 LEU n 
1 659 CYS n 
1 660 LEU n 
1 661 VAL n 
1 662 VAL n 
1 663 ALA n 
1 664 MET n 
1 665 SER n 
1 666 SER n 
1 667 VAL n 
1 668 ALA n 
1 669 THR n 
1 670 ILE n 
1 671 TYR n 
1 672 GLN n 
1 673 LEU n 
1 674 TYR n 
1 675 TRP n 
1 676 ASP n 
1 677 PHE n 
1 678 VAL n 
1 679 LYS n 
1 680 ASP n 
1 681 TRP n 
1 682 GLY n 
1 683 LEU n 
1 684 LEU n 
1 685 GLN n 
1 686 HIS n 
1 687 ASN n 
1 688 SER n 
1 689 ASN n 
1 690 ASN n 
1 691 PRO n 
1 692 TRP n 
1 693 LEU n 
1 694 ARG n 
1 695 ASN n 
1 696 GLN n 
1 697 LEU n 
1 698 MET n 
1 699 LEU n 
1 700 ARG n 
1 701 GLN n 
1 702 LYS n 
1 703 SER n 
1 704 ILE n 
1 705 TYR n 
1 706 TYR n 
1 707 PHE n 
1 708 SER n 
1 709 MET n 
1 710 VAL n 
1 711 LEU n 
1 712 ASN n 
1 713 LEU n 
1 714 VAL n 
1 715 LEU n 
1 716 ARG n 
1 717 LEU n 
1 718 ALA n 
1 719 TRP n 
1 720 LEU n 
1 721 GLN n 
1 722 THR n 
1 723 VAL n 
1 724 LEU n 
1 725 HIS n 
1 726 SER n 
1 727 SER n 
1 728 PHE n 
1 729 GLU n 
1 730 HIS n 
1 731 VAL n 
1 732 ASP n 
1 733 TYR n 
1 734 ARG n 
1 735 VAL n 
1 736 THR n 
1 737 GLY n 
1 738 LEU n 
1 739 PHE n 
1 740 LEU n 
1 741 ALA n 
1 742 ALA n 
1 743 LEU n 
1 744 GLU n 
1 745 VAL n 
1 746 ILE n 
1 747 ARG n 
1 748 ARG n 
1 749 GLY n 
1 750 GLN n 
1 751 TRP n 
1 752 ASN n 
1 753 PHE n 
1 754 TYR n 
1 755 ARG n 
1 756 LEU n 
1 757 GLU n 
1 758 ASN n 
1 759 GLU n 
1 760 HIS n 
1 761 LEU n 
1 762 ASN n 
1 763 ASN n 
1 764 ALA n 
1 765 GLY n 
1 766 LYS n 
1 767 PHE n 
1 768 ARG n 
1 769 ALA n 
1 770 VAL n 
1 771 LYS n 
1 772 THR n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   772 
_entity_src_gen.gene_src_common_name               'Mouse-ear cress' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'PHO1-H1, At1g68740, F14K14.15, F24J5.2' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Arabidopsis thaliana' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     3702 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Spodoptera frugiperda' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7108 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                     ?                                                                      
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                    ?                                                                      
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                  ?                                                                      
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'             ?                                                                      
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                    ?                                                                      
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                   ?                                                                      
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'             ?                                                                      
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                     ?                                                                      
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                   ?                                                                      
'C6 H10 N3 O2 1' 156.162 
IHP non-polymer         . 'INOSITOL HEXAKISPHOSPHATE' 'MYO-INOSITOL HEXAKISPHOSPHATE; INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE' 
'C6 H18 O24 P6'  660.035 
ILE 'L-peptide linking' y ISOLEUCINE                  ?                                                                      
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                     ?                                                                      
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                      ?                                                                      
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                  ?                                                                      
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE               ?                                                                      
'C9 H11 N O2'    165.189 
PO4 non-polymer         . 'PHOSPHATE ION'             ?                                                                      
'O4 P -3'        94.971  
PRO 'L-peptide linking' y PROLINE                     ?                                                                      
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                      ?                                                                      
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                   ?                                                                      
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                  ?                                                                      
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                    ?                                                                      
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                      ?                                                                      
'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   VAL 2   2   ?   ?   ?   A . n 
A 1 3   LYS 3   3   ?   ?   ?   A . n 
A 1 4   PHE 4   4   ?   ?   ?   A . n 
A 1 5   THR 5   5   ?   ?   ?   A . n 
A 1 6   LYS 6   6   ?   ?   ?   A . n 
A 1 7   GLN 7   7   ?   ?   ?   A . n 
A 1 8   PHE 8   8   ?   ?   ?   A . n 
A 1 9   GLU 9   9   ?   ?   ?   A . n 
A 1 10  GLY 10  10  ?   ?   ?   A . n 
A 1 11  GLN 11  11  11  GLN GLN A . n 
A 1 12  LEU 12  12  12  LEU LEU A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  PRO 14  14  14  PRO PRO A . n 
A 1 15  GLU 15  15  15  GLU GLU A . n 
A 1 16  TRP 16  16  16  TRP TRP A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  ASP 18  18  18  ASP ASP A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  PHE 20  20  20  PHE PHE A . n 
A 1 21  VAL 21  21  21  VAL VAL A . n 
A 1 22  ASP 22  22  22  ASP ASP A . n 
A 1 23  TYR 23  23  23  TYR TYR A . n 
A 1 24  SER 24  24  24  SER SER A . n 
A 1 25  GLN 25  25  25  GLN GLN A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  LYS 27  27  27  LYS LYS A . n 
A 1 28  LYS 28  28  28  LYS LYS A . n 
A 1 29  ASP 29  29  29  ASP ASP A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  LYS 31  31  31  LYS LYS A . n 
A 1 32  LYS 32  32  32  LYS LYS A . n 
A 1 33  ILE 33  33  33  ILE ILE A . n 
A 1 34  HIS 34  34  34  HIS HIS A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  PHE 36  36  36  PHE PHE A . n 
A 1 37  THR 37  37  37  THR THR A . n 
A 1 38  ASN 38  38  38  ASN ASN A . n 
A 1 39  GLY 39  39  39  GLY GLY A . n 
A 1 40  VAL 40  40  ?   ?   ?   A . n 
A 1 41  GLU 41  41  ?   ?   ?   A . n 
A 1 42  LYS 42  42  ?   ?   ?   A . n 
A 1 43  LYS 43  43  ?   ?   ?   A . n 
A 1 44  HIS 44  44  ?   ?   ?   A . n 
A 1 45  THR 45  45  ?   ?   ?   A . n 
A 1 46  GLU 46  46  ?   ?   ?   A . n 
A 1 47  THR 47  47  ?   ?   ?   A . n 
A 1 48  SER 48  48  ?   ?   ?   A . n 
A 1 49  LEU 49  49  ?   ?   ?   A . n 
A 1 50  ILE 50  50  ?   ?   ?   A . n 
A 1 51  LYS 51  51  ?   ?   ?   A . n 
A 1 52  THR 52  52  ?   ?   ?   A . n 
A 1 53  VAL 53  53  ?   ?   ?   A . n 
A 1 54  LYS 54  54  ?   ?   ?   A . n 
A 1 55  SER 55  55  ?   ?   ?   A . n 
A 1 56  SER 56  56  ?   ?   ?   A . n 
A 1 57  LEU 57  57  ?   ?   ?   A . n 
A 1 58  GLY 58  58  ?   ?   ?   A . n 
A 1 59  ARG 59  59  ?   ?   ?   A . n 
A 1 60  LEU 60  60  ?   ?   ?   A . n 
A 1 61  SER 61  61  ?   ?   ?   A . n 
A 1 62  ILE 62  62  ?   ?   ?   A . n 
A 1 63  PHE 63  63  ?   ?   ?   A . n 
A 1 64  GLY 64  64  ?   ?   ?   A . n 
A 1 65  ASN 65  65  ?   ?   ?   A . n 
A 1 66  LYS 66  66  ?   ?   ?   A . n 
A 1 67  GLY 67  67  ?   ?   ?   A . n 
A 1 68  ARG 68  68  ?   ?   ?   A . n 
A 1 69  GLU 69  69  ?   ?   ?   A . n 
A 1 70  GLN 70  70  ?   ?   ?   A . n 
A 1 71  SER 71  71  ?   ?   ?   A . n 
A 1 72  ARG 72  72  ?   ?   ?   A . n 
A 1 73  VAL 73  73  73  VAL VAL A . n 
A 1 74  ILE 74  74  74  ILE ILE A . n 
A 1 75  GLN 75  75  75  GLN GLN A . n 
A 1 76  VAL 76  76  76  VAL VAL A . n 
A 1 77  HIS 77  77  77  HIS HIS A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  LYS 79  79  79  LYS LYS A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  SER 82  82  82  SER SER A . n 
A 1 83  SER 83  83  83  SER SER A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  SER 85  85  85  SER SER A . n 
A 1 86  ASN 86  86  86  ASN ASN A . n 
A 1 87  ASN 87  87  87  ASN ASN A . n 
A 1 88  ASP 88  88  88  ASP ASP A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  TYR 90  90  90  TYR TYR A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  THR 92  92  92  THR THR A . n 
A 1 93  GLU 93  93  93  GLU GLU A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  GLU 96  96  96  GLU GLU A . n 
A 1 97  LYS 97  97  97  LYS LYS A . n 
A 1 98  ILE 98  98  98  ILE ILE A . n 
A 1 99  ALA 99  99  99  ALA ALA A . n 
A 1 100 ASP 100 100 100 ASP ASP A . n 
A 1 101 ASP 101 101 101 ASP ASP A . n 
A 1 102 THR 102 102 102 THR THR A . n 
A 1 103 ASP 103 103 103 ASP ASP A . n 
A 1 104 ALA 104 104 104 ALA ALA A . n 
A 1 105 ALA 105 105 105 ALA ALA A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 PHE 109 109 109 PHE PHE A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 CYS 111 111 111 CYS CYS A . n 
A 1 112 LEU 112 112 112 LEU LEU A . n 
A 1 113 ASP 113 113 113 ASP ASP A . n 
A 1 114 MET 114 114 114 MET MET A . n 
A 1 115 GLN 115 115 115 GLN GLN A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 ASN 117 117 117 ASN ASN A . n 
A 1 118 LYS 118 118 118 LYS LYS A . n 
A 1 119 VAL 119 119 119 VAL VAL A . n 
A 1 120 ASN 120 120 120 ASN ASN A . n 
A 1 121 GLN 121 121 121 GLN GLN A . n 
A 1 122 PHE 122 122 122 PHE PHE A . n 
A 1 123 TYR 123 123 123 TYR TYR A . n 
A 1 124 LYS 124 124 124 LYS LYS A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 LYS 126 126 126 LYS LYS A . n 
A 1 127 GLU 127 127 127 GLU GLU A . n 
A 1 128 LYS 128 128 128 LYS LYS A . n 
A 1 129 GLU 129 129 129 GLU GLU A . n 
A 1 130 PHE 130 130 130 PHE PHE A . n 
A 1 131 LEU 131 131 131 LEU LEU A . n 
A 1 132 GLU 132 132 132 GLU GLU A . n 
A 1 133 ARG 133 133 133 ARG ARG A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 GLU 135 135 135 GLU GLU A . n 
A 1 136 CYS 136 136 136 CYS CYS A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 LYS 138 138 138 LYS LYS A . n 
A 1 139 LYS 139 139 139 LYS LYS A . n 
A 1 140 GLN 140 140 140 GLN GLN A . n 
A 1 141 MET 141 141 141 MET MET A . n 
A 1 142 ASP 142 142 142 ASP ASP A . n 
A 1 143 ILE 143 143 143 ILE ILE A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 ILE 145 145 145 ILE ILE A . n 
A 1 146 GLU 146 146 146 GLU GLU A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 LYS 148 148 148 LYS LYS A . n 
A 1 149 ASP 149 149 149 ASP ASP A . n 
A 1 150 ALA 150 150 150 ALA ALA A . n 
A 1 151 PHE 151 151 151 PHE PHE A . n 
A 1 152 LYS 152 152 152 LYS LYS A . n 
A 1 153 GLN 153 153 153 GLN GLN A . n 
A 1 154 LYS 154 154 154 LYS LYS A . n 
A 1 155 GLN 155 155 155 GLN GLN A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 ASN 157 157 157 ASN ASN A . n 
A 1 158 GLY 158 158 ?   ?   ?   A . n 
A 1 159 GLU 159 159 ?   ?   ?   A . n 
A 1 160 SER 160 160 ?   ?   ?   A . n 
A 1 161 THR 161 161 ?   ?   ?   A . n 
A 1 162 GLN 162 162 ?   ?   ?   A . n 
A 1 163 GLU 163 163 ?   ?   ?   A . n 
A 1 164 SER 164 164 ?   ?   ?   A . n 
A 1 165 LYS 165 165 ?   ?   ?   A . n 
A 1 166 GLU 166 166 ?   ?   ?   A . n 
A 1 167 ASP 167 167 ?   ?   ?   A . n 
A 1 168 ASP 168 168 ?   ?   ?   A . n 
A 1 169 SER 169 169 ?   ?   ?   A . n 
A 1 170 ILE 170 170 ?   ?   ?   A . n 
A 1 171 SER 171 171 ?   ?   ?   A . n 
A 1 172 CYS 172 172 ?   ?   ?   A . n 
A 1 173 THR 173 173 ?   ?   ?   A . n 
A 1 174 ILE 174 174 ?   ?   ?   A . n 
A 1 175 SER 175 175 ?   ?   ?   A . n 
A 1 176 CYS 176 176 ?   ?   ?   A . n 
A 1 177 GLU 177 177 ?   ?   ?   A . n 
A 1 178 TYR 178 178 ?   ?   ?   A . n 
A 1 179 ASP 179 179 ?   ?   ?   A . n 
A 1 180 SER 180 180 ?   ?   ?   A . n 
A 1 181 VAL 181 181 ?   ?   ?   A . n 
A 1 182 ARG 182 182 ?   ?   ?   A . n 
A 1 183 GLY 183 183 ?   ?   ?   A . n 
A 1 184 ARG 184 184 ?   ?   ?   A . n 
A 1 185 THR 185 185 ?   ?   ?   A . n 
A 1 186 GLU 186 186 ?   ?   ?   A . n 
A 1 187 GLU 187 187 ?   ?   ?   A . n 
A 1 188 MET 188 188 ?   ?   ?   A . n 
A 1 189 GLN 189 189 ?   ?   ?   A . n 
A 1 190 LEU 190 190 ?   ?   ?   A . n 
A 1 191 GLN 191 191 ?   ?   ?   A . n 
A 1 192 VAL 192 192 ?   ?   ?   A . n 
A 1 193 SER 193 193 ?   ?   ?   A . n 
A 1 194 CYS 194 194 ?   ?   ?   A . n 
A 1 195 LEU 195 195 ?   ?   ?   A . n 
A 1 196 ASP 196 196 ?   ?   ?   A . n 
A 1 197 ASN 197 197 ?   ?   ?   A . n 
A 1 198 LEU 198 198 ?   ?   ?   A . n 
A 1 199 GLU 199 199 ?   ?   ?   A . n 
A 1 200 ASP 200 200 ?   ?   ?   A . n 
A 1 201 ASN 201 201 ?   ?   ?   A . n 
A 1 202 GLY 202 202 ?   ?   ?   A . n 
A 1 203 GLU 203 203 ?   ?   ?   A . n 
A 1 204 GLU 204 204 ?   ?   ?   A . n 
A 1 205 ALA 205 205 ?   ?   ?   A . n 
A 1 206 LEU 206 206 ?   ?   ?   A . n 
A 1 207 GLU 207 207 ?   ?   ?   A . n 
A 1 208 SER 208 208 ?   ?   ?   A . n 
A 1 209 LEU 209 209 ?   ?   ?   A . n 
A 1 210 GLY 210 210 ?   ?   ?   A . n 
A 1 211 SER 211 211 ?   ?   ?   A . n 
A 1 212 GLU 212 212 ?   ?   ?   A . n 
A 1 213 GLU 213 213 ?   ?   ?   A . n 
A 1 214 PRO 214 214 ?   ?   ?   A . n 
A 1 215 ILE 215 215 ?   ?   ?   A . n 
A 1 216 LYS 216 216 ?   ?   ?   A . n 
A 1 217 ALA 217 217 ?   ?   ?   A . n 
A 1 218 ASN 218 218 ?   ?   ?   A . n 
A 1 219 ASN 219 219 ?   ?   ?   A . n 
A 1 220 GLU 220 220 ?   ?   ?   A . n 
A 1 221 ASP 221 221 ?   ?   ?   A . n 
A 1 222 SER 222 222 ?   ?   ?   A . n 
A 1 223 LYS 223 223 ?   ?   ?   A . n 
A 1 224 LEU 224 224 ?   ?   ?   A . n 
A 1 225 THR 225 225 ?   ?   ?   A . n 
A 1 226 THR 226 226 ?   ?   ?   A . n 
A 1 227 VAL 227 227 ?   ?   ?   A . n 
A 1 228 SER 228 228 ?   ?   ?   A . n 
A 1 229 SER 229 229 ?   ?   ?   A . n 
A 1 230 ARG 230 230 ?   ?   ?   A . n 
A 1 231 VAL 231 231 ?   ?   ?   A . n 
A 1 232 PHE 232 232 ?   ?   ?   A . n 
A 1 233 SER 233 233 ?   ?   ?   A . n 
A 1 234 CYS 234 234 ?   ?   ?   A . n 
A 1 235 GLN 235 235 ?   ?   ?   A . n 
A 1 236 GLY 236 236 ?   ?   ?   A . n 
A 1 237 LYS 237 237 ?   ?   ?   A . n 
A 1 238 ASN 238 238 ?   ?   ?   A . n 
A 1 239 VAL 239 239 ?   ?   ?   A . n 
A 1 240 LYS 240 240 ?   ?   ?   A . n 
A 1 241 ILE 241 241 ?   ?   ?   A . n 
A 1 242 LYS 242 242 ?   ?   ?   A . n 
A 1 243 ILE 243 243 ?   ?   ?   A . n 
A 1 244 PRO 244 244 ?   ?   ?   A . n 
A 1 245 LEU 245 245 ?   ?   ?   A . n 
A 1 246 THR 246 246 ?   ?   ?   A . n 
A 1 247 ASN 247 247 ?   ?   ?   A . n 
A 1 248 PRO 248 248 ?   ?   ?   A . n 
A 1 249 SER 249 249 ?   ?   ?   A . n 
A 1 250 ARG 250 250 ?   ?   ?   A . n 
A 1 251 THR 251 251 ?   ?   ?   A . n 
A 1 252 PHE 252 252 ?   ?   ?   A . n 
A 1 253 SER 253 253 ?   ?   ?   A . n 
A 1 254 ALA 254 254 ?   ?   ?   A . n 
A 1 255 ILE 255 255 ?   ?   ?   A . n 
A 1 256 SER 256 256 ?   ?   ?   A . n 
A 1 257 TYR 257 257 ?   ?   ?   A . n 
A 1 258 LEU 258 258 ?   ?   ?   A . n 
A 1 259 ILE 259 259 ?   ?   ?   A . n 
A 1 260 ASN 260 260 ?   ?   ?   A . n 
A 1 261 GLN 261 261 ?   ?   ?   A . n 
A 1 262 SER 262 262 ?   ?   ?   A . n 
A 1 263 SER 263 263 ?   ?   ?   A . n 
A 1 264 SER 264 264 ?   ?   ?   A . n 
A 1 265 LYS 265 265 ?   ?   ?   A . n 
A 1 266 LYS 266 266 ?   ?   ?   A . n 
A 1 267 ASN 267 267 ?   ?   ?   A . n 
A 1 268 GLY 268 268 ?   ?   ?   A . n 
A 1 269 PRO 269 269 ?   ?   ?   A . n 
A 1 270 ASP 270 270 ?   ?   ?   A . n 
A 1 271 GLY 271 271 ?   ?   ?   A . n 
A 1 272 GLY 272 272 ?   ?   ?   A . n 
A 1 273 ASN 273 273 ?   ?   ?   A . n 
A 1 274 LYS 274 274 ?   ?   ?   A . n 
A 1 275 LEU 275 275 ?   ?   ?   A . n 
A 1 276 GLN 276 276 ?   ?   ?   A . n 
A 1 277 ILE 277 277 ?   ?   ?   A . n 
A 1 278 SER 278 278 ?   ?   ?   A . n 
A 1 279 LYS 279 279 ?   ?   ?   A . n 
A 1 280 LYS 280 280 280 LYS LYS A . n 
A 1 281 LYS 281 281 281 LYS LYS A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 SER 283 283 283 SER SER A . n 
A 1 284 HIS 284 284 284 HIS HIS A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 GLU 286 286 286 GLU GLU A . n 
A 1 287 LYS 287 287 287 LYS LYS A . n 
A 1 288 MET 288 288 288 MET MET A . n 
A 1 289 ILE 289 289 289 ILE ILE A . n 
A 1 290 LYS 290 290 290 LYS LYS A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 ALA 292 292 292 ALA ALA A . n 
A 1 293 LEU 293 293 293 LEU LEU A . n 
A 1 294 THR 294 294 294 THR THR A . n 
A 1 295 GLU 295 295 295 GLU GLU A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 PHE 297 297 297 PHE PHE A . n 
A 1 298 LYS 298 298 298 LYS LYS A . n 
A 1 299 GLY 299 299 299 GLY GLY A . n 
A 1 300 LEU 300 300 300 LEU LEU A . n 
A 1 301 ASN 301 301 301 ASN ASN A . n 
A 1 302 TYR 302 302 302 TYR TYR A . n 
A 1 303 LEU 303 303 303 LEU LEU A . n 
A 1 304 LYS 304 304 304 LYS LYS A . n 
A 1 305 THR 305 305 305 THR THR A . n 
A 1 306 TYR 306 306 306 TYR TYR A . n 
A 1 307 ARG 307 307 307 ARG ARG A . n 
A 1 308 ASN 308 308 308 ASN ASN A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 ASN 310 310 310 ASN ASN A . n 
A 1 311 ILE 311 311 311 ILE ILE A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 ALA 313 313 313 ALA ALA A . n 
A 1 314 PHE 314 314 314 PHE PHE A . n 
A 1 315 MET 315 315 315 MET MET A . n 
A 1 316 ASN 316 316 316 ASN ASN A . n 
A 1 317 ILE 317 317 317 ILE ILE A . n 
A 1 318 LEU 318 318 318 LEU LEU A . n 
A 1 319 LYS 319 319 319 LYS LYS A . n 
A 1 320 LYS 320 320 320 LYS LYS A . n 
A 1 321 PHE 321 321 321 PHE PHE A . n 
A 1 322 ASP 322 322 322 ASP ASP A . n 
A 1 323 LYS 323 323 323 LYS LYS A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 THR 325 325 325 THR THR A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 LYS 327 327 327 LYS LYS A . n 
A 1 328 GLN 328 328 328 GLN GLN A . n 
A 1 329 ILE 329 329 329 ILE ILE A . n 
A 1 330 LEU 330 330 330 LEU LEU A . n 
A 1 331 PRO 331 331 331 PRO PRO A . n 
A 1 332 ILE 332 332 332 ILE ILE A . n 
A 1 333 TYR 333 333 333 TYR TYR A . n 
A 1 334 LEU 334 334 334 LEU LEU A . n 
A 1 335 LYS 335 335 335 LYS LYS A . n 
A 1 336 VAL 336 336 336 VAL VAL A . n 
A 1 337 VAL 337 337 337 VAL VAL A . n 
A 1 338 GLU 338 338 338 GLU GLU A . n 
A 1 339 SER 339 339 339 SER SER A . n 
A 1 340 SER 340 340 340 SER SER A . n 
A 1 341 TYR 341 341 341 TYR TYR A . n 
A 1 342 PHE 342 342 342 PHE PHE A . n 
A 1 343 ASN 343 343 343 ASN ASN A . n 
A 1 344 ILE 344 344 344 ILE ILE A . n 
A 1 345 SER 345 345 345 SER SER A . n 
A 1 346 ASP 346 346 346 ASP ASP A . n 
A 1 347 LYS 347 347 347 LYS LYS A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 MET 349 349 349 MET MET A . n 
A 1 350 ILE 350 350 350 ILE ILE A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 SER 352 352 352 SER SER A . n 
A 1 353 ASP 353 353 353 ASP ASP A . n 
A 1 354 GLU 354 354 354 GLU GLU A . n 
A 1 355 VAL 355 355 355 VAL VAL A . n 
A 1 356 GLU 356 356 356 GLU GLU A . n 
A 1 357 GLU 357 357 357 GLU GLU A . n 
A 1 358 TRP 358 358 358 TRP TRP A . n 
A 1 359 PHE 359 359 359 PHE PHE A . n 
A 1 360 ILE 360 360 360 ILE ILE A . n 
A 1 361 LYS 361 361 361 LYS LYS A . n 
A 1 362 HIS 362 362 362 HIS HIS A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 ALA 364 364 364 ALA ALA A . n 
A 1 365 GLY 365 365 365 GLY GLY A . n 
A 1 366 GLU 366 366 366 GLU GLU A . n 
A 1 367 ASN 367 367 367 ASN ASN A . n 
A 1 368 ARG 368 368 368 ARG ARG A . n 
A 1 369 ARG 369 369 369 ARG ARG A . n 
A 1 370 LYS 370 370 370 LYS LYS A . n 
A 1 371 ALA 371 371 371 ALA ALA A . n 
A 1 372 MET 372 372 372 MET MET A . n 
A 1 373 LYS 373 373 373 LYS LYS A . n 
A 1 374 TYR 374 374 374 TYR TYR A . n 
A 1 375 LEU 375 375 375 LEU LEU A . n 
A 1 376 LYS 376 376 376 LYS LYS A . n 
A 1 377 PRO 377 377 377 PRO PRO A . n 
A 1 378 HIS 378 378 378 HIS HIS A . n 
A 1 379 HIS 379 379 379 HIS HIS A . n 
A 1 380 ARG 380 380 380 ARG ARG A . n 
A 1 381 LYS 381 381 381 LYS LYS A . n 
A 1 382 GLU 382 382 382 GLU GLU A . n 
A 1 383 SER 383 383 383 SER SER A . n 
A 1 384 HIS 384 384 384 HIS HIS A . n 
A 1 385 SER 385 385 385 SER SER A . n 
A 1 386 VAL 386 386 386 VAL VAL A . n 
A 1 387 THR 387 387 387 THR THR A . n 
A 1 388 PHE 388 388 388 PHE PHE A . n 
A 1 389 PHE 389 389 389 PHE PHE A . n 
A 1 390 ILE 390 390 390 ILE ILE A . n 
A 1 391 GLY 391 391 391 GLY GLY A . n 
A 1 392 LEU 392 392 392 LEU LEU A . n 
A 1 393 PHE 393 393 393 PHE PHE A . n 
A 1 394 THR 394 394 394 THR THR A . n 
A 1 395 GLY 395 395 395 GLY GLY A . n 
A 1 396 CYS 396 396 396 CYS CYS A . n 
A 1 397 PHE 397 397 397 PHE PHE A . n 
A 1 398 VAL 398 398 398 VAL VAL A . n 
A 1 399 ALA 399 399 399 ALA ALA A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 LEU 401 401 401 LEU LEU A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 GLY 403 403 403 GLY GLY A . n 
A 1 404 TYR 404 404 404 TYR TYR A . n 
A 1 405 ILE 405 405 405 ILE ILE A . n 
A 1 406 ILE 406 406 406 ILE ILE A . n 
A 1 407 VAL 407 407 407 VAL VAL A . n 
A 1 408 ALA 408 408 408 ALA ALA A . n 
A 1 409 HIS 409 409 409 HIS HIS A . n 
A 1 410 LEU 410 410 410 LEU LEU A . n 
A 1 411 THR 411 411 411 THR THR A . n 
A 1 412 GLY 412 412 412 GLY GLY A . n 
A 1 413 MET 413 413 413 MET MET A . n 
A 1 414 TYR 414 414 414 TYR TYR A . n 
A 1 415 ARG 415 415 415 ARG ARG A . n 
A 1 416 GLN 416 416 416 GLN GLN A . n 
A 1 417 HIS 417 417 417 HIS HIS A . n 
A 1 418 SER 418 418 418 SER SER A . n 
A 1 419 ALA 419 419 419 ALA ALA A . n 
A 1 420 ASN 420 420 420 ASN ASN A . n 
A 1 421 THR 421 421 421 THR THR A . n 
A 1 422 PHE 422 422 422 PHE PHE A . n 
A 1 423 TYR 423 423 423 TYR TYR A . n 
A 1 424 MET 424 424 424 MET MET A . n 
A 1 425 GLU 425 425 425 GLU GLU A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 ALA 427 427 427 ALA ALA A . n 
A 1 428 TYR 428 428 428 TYR TYR A . n 
A 1 429 PRO 429 429 429 PRO PRO A . n 
A 1 430 VAL 430 430 430 VAL VAL A . n 
A 1 431 LEU 431 431 431 LEU LEU A . n 
A 1 432 SER 432 432 432 SER SER A . n 
A 1 433 MET 433 433 433 MET MET A . n 
A 1 434 PHE 434 434 434 PHE PHE A . n 
A 1 435 GLY 435 435 435 GLY GLY A . n 
A 1 436 LEU 436 436 436 LEU LEU A . n 
A 1 437 LEU 437 437 437 LEU LEU A . n 
A 1 438 PHE 438 438 438 PHE PHE A . n 
A 1 439 LEU 439 439 439 LEU LEU A . n 
A 1 440 HIS 440 440 440 HIS HIS A . n 
A 1 441 LEU 441 441 441 LEU LEU A . n 
A 1 442 PHE 442 442 442 PHE PHE A . n 
A 1 443 LEU 443 443 443 LEU LEU A . n 
A 1 444 TYR 444 444 444 TYR TYR A . n 
A 1 445 GLY 445 445 445 GLY GLY A . n 
A 1 446 CYS 446 446 446 CYS CYS A . n 
A 1 447 ASN 447 447 447 ASN ASN A . n 
A 1 448 ILE 448 448 448 ILE ILE A . n 
A 1 449 PHE 449 449 449 PHE PHE A . n 
A 1 450 MET 450 450 450 MET MET A . n 
A 1 451 TRP 451 451 451 TRP TRP A . n 
A 1 452 ARG 452 452 452 ARG ARG A . n 
A 1 453 LYS 453 453 453 LYS LYS A . n 
A 1 454 ALA 454 454 454 ALA ALA A . n 
A 1 455 ARG 455 455 455 ARG ARG A . n 
A 1 456 ILE 456 456 456 ILE ILE A . n 
A 1 457 ASN 457 457 457 ASN ASN A . n 
A 1 458 TYR 458 458 458 TYR TYR A . n 
A 1 459 SER 459 459 459 SER SER A . n 
A 1 460 PHE 460 460 460 PHE PHE A . n 
A 1 461 ILE 461 461 461 ILE ILE A . n 
A 1 462 PHE 462 462 462 PHE PHE A . n 
A 1 463 GLU 463 463 463 GLU GLU A . n 
A 1 464 LEU 464 464 464 LEU LEU A . n 
A 1 465 GLY 465 465 465 GLY GLY A . n 
A 1 466 SER 466 466 466 SER SER A . n 
A 1 467 LYS 467 467 467 LYS LYS A . n 
A 1 468 ASN 468 468 468 ASN ASN A . n 
A 1 469 GLU 469 469 469 GLU GLU A . n 
A 1 470 LEU 470 470 470 LEU LEU A . n 
A 1 471 LYS 471 471 471 LYS LYS A . n 
A 1 472 TYR 472 472 472 TYR TYR A . n 
A 1 473 ARG 473 473 473 ARG ARG A . n 
A 1 474 ASP 474 474 474 ASP ASP A . n 
A 1 475 VAL 475 475 475 VAL VAL A . n 
A 1 476 PHE 476 476 476 PHE PHE A . n 
A 1 477 LEU 477 477 477 LEU LEU A . n 
A 1 478 ILE 478 478 478 ILE ILE A . n 
A 1 479 CYS 479 479 479 CYS CYS A . n 
A 1 480 THR 480 480 480 THR THR A . n 
A 1 481 ALA 481 481 481 ALA ALA A . n 
A 1 482 SER 482 482 482 SER SER A . n 
A 1 483 MET 483 483 483 MET MET A . n 
A 1 484 SER 484 484 484 SER SER A . n 
A 1 485 ALA 485 485 485 ALA ALA A . n 
A 1 486 ILE 486 486 486 ILE ILE A . n 
A 1 487 ALA 487 487 487 ALA ALA A . n 
A 1 488 GLY 488 488 488 GLY GLY A . n 
A 1 489 VAL 489 489 489 VAL VAL A . n 
A 1 490 MET 490 490 490 MET MET A . n 
A 1 491 PHE 491 491 491 PHE PHE A . n 
A 1 492 VAL 492 492 492 VAL VAL A . n 
A 1 493 HIS 493 493 493 HIS HIS A . n 
A 1 494 LEU 494 494 494 LEU LEU A . n 
A 1 495 SER 495 495 495 SER SER A . n 
A 1 496 LEU 496 496 496 LEU LEU A . n 
A 1 497 LEU 497 497 497 LEU LEU A . n 
A 1 498 GLU 498 498 498 GLU GLU A . n 
A 1 499 LYS 499 499 499 LYS LYS A . n 
A 1 500 GLY 500 500 500 GLY GLY A . n 
A 1 501 TYR 501 501 501 TYR TYR A . n 
A 1 502 SER 502 502 502 SER SER A . n 
A 1 503 PHE 503 503 503 PHE PHE A . n 
A 1 504 ARG 504 504 504 ARG ARG A . n 
A 1 505 GLN 505 505 505 GLN GLN A . n 
A 1 506 VAL 506 506 506 VAL VAL A . n 
A 1 507 GLN 507 507 507 GLN GLN A . n 
A 1 508 VAL 508 508 508 VAL VAL A . n 
A 1 509 ILE 509 509 509 ILE ILE A . n 
A 1 510 PRO 510 510 510 PRO PRO A . n 
A 1 511 GLY 511 511 511 GLY GLY A . n 
A 1 512 LEU 512 512 512 LEU LEU A . n 
A 1 513 LEU 513 513 513 LEU LEU A . n 
A 1 514 LEU 514 514 514 LEU LEU A . n 
A 1 515 LEU 515 515 515 LEU LEU A . n 
A 1 516 GLY 516 516 516 GLY GLY A . n 
A 1 517 PHE 517 517 517 PHE PHE A . n 
A 1 518 LEU 518 518 518 LEU LEU A . n 
A 1 519 LEU 519 519 519 LEU LEU A . n 
A 1 520 ILE 520 520 520 ILE ILE A . n 
A 1 521 LEU 521 521 521 LEU LEU A . n 
A 1 522 ILE 522 522 522 ILE ILE A . n 
A 1 523 CYS 523 523 523 CYS CYS A . n 
A 1 524 PRO 524 524 524 PRO PRO A . n 
A 1 525 LEU 525 525 525 LEU LEU A . n 
A 1 526 ASN 526 526 526 ASN ASN A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 PHE 528 528 528 PHE PHE A . n 
A 1 529 TYR 529 529 529 TYR TYR A . n 
A 1 530 LYS 530 530 530 LYS LYS A . n 
A 1 531 SER 531 531 531 SER SER A . n 
A 1 532 SER 532 532 532 SER SER A . n 
A 1 533 ARG 533 533 533 ARG ARG A . n 
A 1 534 TYR 534 534 534 TYR TYR A . n 
A 1 535 ARG 535 535 535 ARG ARG A . n 
A 1 536 LEU 536 536 536 LEU LEU A . n 
A 1 537 ILE 537 537 537 ILE ILE A . n 
A 1 538 SER 538 538 538 SER SER A . n 
A 1 539 VAL 539 539 539 VAL VAL A . n 
A 1 540 ILE 540 540 540 ILE ILE A . n 
A 1 541 ARG 541 541 541 ARG ARG A . n 
A 1 542 ASN 542 542 542 ASN ASN A . n 
A 1 543 ILE 543 543 543 ILE ILE A . n 
A 1 544 VAL 544 544 544 VAL VAL A . n 
A 1 545 PHE 545 545 545 PHE PHE A . n 
A 1 546 SER 546 546 546 SER SER A . n 
A 1 547 PRO 547 547 547 PRO PRO A . n 
A 1 548 LEU 548 548 548 LEU LEU A . n 
A 1 549 TYR 549 549 549 TYR TYR A . n 
A 1 550 LYS 550 550 550 LYS LYS A . n 
A 1 551 VAL 551 551 551 VAL VAL A . n 
A 1 552 VAL 552 552 552 VAL VAL A . n 
A 1 553 MET 553 553 553 MET MET A . n 
A 1 554 LEU 554 554 554 LEU LEU A . n 
A 1 555 ASP 555 555 555 ASP ASP A . n 
A 1 556 PHE 556 556 556 PHE PHE A . n 
A 1 557 PHE 557 557 557 PHE PHE A . n 
A 1 558 MET 558 558 558 MET MET A . n 
A 1 559 ALA 559 559 559 ALA ALA A . n 
A 1 560 ASP 560 560 560 ASP ASP A . n 
A 1 561 GLN 561 561 561 GLN GLN A . n 
A 1 562 LEU 562 562 562 LEU LEU A . n 
A 1 563 CYS 563 563 563 CYS CYS A . n 
A 1 564 SER 564 564 564 SER SER A . n 
A 1 565 GLN 565 565 565 GLN GLN A . n 
A 1 566 VAL 566 566 566 VAL VAL A . n 
A 1 567 PRO 567 567 567 PRO PRO A . n 
A 1 568 MET 568 568 568 MET MET A . n 
A 1 569 LEU 569 569 569 LEU LEU A . n 
A 1 570 ARG 570 570 570 ARG ARG A . n 
A 1 571 ASN 571 571 571 ASN ASN A . n 
A 1 572 LEU 572 572 572 LEU LEU A . n 
A 1 573 GLU 573 573 573 GLU GLU A . n 
A 1 574 TYR 574 574 574 TYR TYR A . n 
A 1 575 ILE 575 575 575 ILE ILE A . n 
A 1 576 ALA 576 576 576 ALA ALA A . n 
A 1 577 CYS 577 577 577 CYS CYS A . n 
A 1 578 TYR 578 578 578 TYR TYR A . n 
A 1 579 TYR 579 579 579 TYR TYR A . n 
A 1 580 ILE 580 580 580 ILE ILE A . n 
A 1 581 THR 581 581 581 THR THR A . n 
A 1 582 GLY 582 582 582 GLY GLY A . n 
A 1 583 SER 583 583 583 SER SER A . n 
A 1 584 TYR 584 584 584 TYR TYR A . n 
A 1 585 ALA 585 585 585 ALA ALA A . n 
A 1 586 THR 586 586 586 THR THR A . n 
A 1 587 GLN 587 587 587 GLN GLN A . n 
A 1 588 ASP 588 588 588 ASP ASP A . n 
A 1 589 TYR 589 589 589 TYR TYR A . n 
A 1 590 GLU 590 590 590 GLU GLU A . n 
A 1 591 TYR 591 591 591 TYR TYR A . n 
A 1 592 CYS 592 592 592 CYS CYS A . n 
A 1 593 MET 593 593 593 MET MET A . n 
A 1 594 ARG 594 594 594 ARG ARG A . n 
A 1 595 VAL 595 595 595 VAL VAL A . n 
A 1 596 LYS 596 596 596 LYS LYS A . n 
A 1 597 TYR 597 597 597 TYR TYR A . n 
A 1 598 TYR 598 598 598 TYR TYR A . n 
A 1 599 ARG 599 599 599 ARG ARG A . n 
A 1 600 ASP 600 600 600 ASP ASP A . n 
A 1 601 LEU 601 601 601 LEU LEU A . n 
A 1 602 ALA 602 602 602 ALA ALA A . n 
A 1 603 TYR 603 603 603 TYR TYR A . n 
A 1 604 ALA 604 604 604 ALA ALA A . n 
A 1 605 VAL 605 605 605 VAL VAL A . n 
A 1 606 SER 606 606 606 SER SER A . n 
A 1 607 PHE 607 607 607 PHE PHE A . n 
A 1 608 LEU 608 608 608 LEU LEU A . n 
A 1 609 PRO 609 609 609 PRO PRO A . n 
A 1 610 TYR 610 610 610 TYR TYR A . n 
A 1 611 TYR 611 611 611 TYR TYR A . n 
A 1 612 TRP 612 612 612 TRP TRP A . n 
A 1 613 ARG 613 613 613 ARG ARG A . n 
A 1 614 ALA 614 614 614 ALA ALA A . n 
A 1 615 MET 615 615 615 MET MET A . n 
A 1 616 GLN 616 616 616 GLN GLN A . n 
A 1 617 CYS 617 617 617 CYS CYS A . n 
A 1 618 ALA 618 618 618 ALA ALA A . n 
A 1 619 ARG 619 619 619 ARG ARG A . n 
A 1 620 ARG 620 620 620 ARG ARG A . n 
A 1 621 TRP 621 621 621 TRP TRP A . n 
A 1 622 PHE 622 622 622 PHE PHE A . n 
A 1 623 ASP 623 623 623 ASP ASP A . n 
A 1 624 GLU 624 624 624 GLU GLU A . n 
A 1 625 GLY 625 625 625 GLY GLY A . n 
A 1 626 GLU 626 626 626 GLU GLU A . n 
A 1 627 THR 627 627 627 THR THR A . n 
A 1 628 SER 628 628 628 SER SER A . n 
A 1 629 HIS 629 629 629 HIS HIS A . n 
A 1 630 LEU 630 630 630 LEU LEU A . n 
A 1 631 VAL 631 631 631 VAL VAL A . n 
A 1 632 ASN 632 632 632 ASN ASN A . n 
A 1 633 LEU 633 633 633 LEU LEU A . n 
A 1 634 GLY 634 634 634 GLY GLY A . n 
A 1 635 LYS 635 635 635 LYS LYS A . n 
A 1 636 TYR 636 636 636 TYR TYR A . n 
A 1 637 VAL 637 637 637 VAL VAL A . n 
A 1 638 SER 638 638 638 SER SER A . n 
A 1 639 ALA 639 639 639 ALA ALA A . n 
A 1 640 MET 640 640 640 MET MET A . n 
A 1 641 LEU 641 641 641 LEU LEU A . n 
A 1 642 ALA 642 642 642 ALA ALA A . n 
A 1 643 ALA 643 643 643 ALA ALA A . n 
A 1 644 GLY 644 644 644 GLY GLY A . n 
A 1 645 THR 645 645 645 THR THR A . n 
A 1 646 LYS 646 646 646 LYS LYS A . n 
A 1 647 VAL 647 647 647 VAL VAL A . n 
A 1 648 ALA 648 648 648 ALA ALA A . n 
A 1 649 TYR 649 649 649 TYR TYR A . n 
A 1 650 GLU 650 650 650 GLU GLU A . n 
A 1 651 LYS 651 651 651 LYS LYS A . n 
A 1 652 GLU 652 652 652 GLU GLU A . n 
A 1 653 ARG 653 653 653 ARG ARG A . n 
A 1 654 SER 654 654 654 SER SER A . n 
A 1 655 LEU 655 655 655 LEU LEU A . n 
A 1 656 GLY 656 656 656 GLY GLY A . n 
A 1 657 TRP 657 657 657 TRP TRP A . n 
A 1 658 LEU 658 658 658 LEU LEU A . n 
A 1 659 CYS 659 659 659 CYS CYS A . n 
A 1 660 LEU 660 660 660 LEU LEU A . n 
A 1 661 VAL 661 661 661 VAL VAL A . n 
A 1 662 VAL 662 662 662 VAL VAL A . n 
A 1 663 ALA 663 663 663 ALA ALA A . n 
A 1 664 MET 664 664 664 MET MET A . n 
A 1 665 SER 665 665 665 SER SER A . n 
A 1 666 SER 666 666 666 SER SER A . n 
A 1 667 VAL 667 667 667 VAL VAL A . n 
A 1 668 ALA 668 668 668 ALA ALA A . n 
A 1 669 THR 669 669 669 THR THR A . n 
A 1 670 ILE 670 670 670 ILE ILE A . n 
A 1 671 TYR 671 671 671 TYR TYR A . n 
A 1 672 GLN 672 672 672 GLN GLN A . n 
A 1 673 LEU 673 673 673 LEU LEU A . n 
A 1 674 TYR 674 674 674 TYR TYR A . n 
A 1 675 TRP 675 675 675 TRP TRP A . n 
A 1 676 ASP 676 676 676 ASP ASP A . n 
A 1 677 PHE 677 677 677 PHE PHE A . n 
A 1 678 VAL 678 678 678 VAL VAL A . n 
A 1 679 LYS 679 679 679 LYS LYS A . n 
A 1 680 ASP 680 680 680 ASP ASP A . n 
A 1 681 TRP 681 681 681 TRP TRP A . n 
A 1 682 GLY 682 682 682 GLY GLY A . n 
A 1 683 LEU 683 683 683 LEU LEU A . n 
A 1 684 LEU 684 684 684 LEU LEU A . n 
A 1 685 GLN 685 685 685 GLN GLN A . n 
A 1 686 HIS 686 686 686 HIS HIS A . n 
A 1 687 ASN 687 687 687 ASN ASN A . n 
A 1 688 SER 688 688 688 SER SER A . n 
A 1 689 ASN 689 689 689 ASN ASN A . n 
A 1 690 ASN 690 690 690 ASN ASN A . n 
A 1 691 PRO 691 691 691 PRO PRO A . n 
A 1 692 TRP 692 692 692 TRP TRP A . n 
A 1 693 LEU 693 693 693 LEU LEU A . n 
A 1 694 ARG 694 694 694 ARG ARG A . n 
A 1 695 ASN 695 695 695 ASN ASN A . n 
A 1 696 GLN 696 696 696 GLN GLN A . n 
A 1 697 LEU 697 697 697 LEU LEU A . n 
A 1 698 MET 698 698 698 MET MET A . n 
A 1 699 LEU 699 699 699 LEU LEU A . n 
A 1 700 ARG 700 700 700 ARG ARG A . n 
A 1 701 GLN 701 701 701 GLN GLN A . n 
A 1 702 LYS 702 702 702 LYS LYS A . n 
A 1 703 SER 703 703 703 SER SER A . n 
A 1 704 ILE 704 704 704 ILE ILE A . n 
A 1 705 TYR 705 705 705 TYR TYR A . n 
A 1 706 TYR 706 706 706 TYR TYR A . n 
A 1 707 PHE 707 707 707 PHE PHE A . n 
A 1 708 SER 708 708 708 SER SER A . n 
A 1 709 MET 709 709 709 MET MET A . n 
A 1 710 VAL 710 710 710 VAL VAL A . n 
A 1 711 LEU 711 711 711 LEU LEU A . n 
A 1 712 ASN 712 712 712 ASN ASN A . n 
A 1 713 LEU 713 713 713 LEU LEU A . n 
A 1 714 VAL 714 714 714 VAL VAL A . n 
A 1 715 LEU 715 715 715 LEU LEU A . n 
A 1 716 ARG 716 716 716 ARG ARG A . n 
A 1 717 LEU 717 717 717 LEU LEU A . n 
A 1 718 ALA 718 718 718 ALA ALA A . n 
A 1 719 TRP 719 719 719 TRP TRP A . n 
A 1 720 LEU 720 720 720 LEU LEU A . n 
A 1 721 GLN 721 721 721 GLN GLN A . n 
A 1 722 THR 722 722 722 THR THR A . n 
A 1 723 VAL 723 723 723 VAL VAL A . n 
A 1 724 LEU 724 724 724 LEU LEU A . n 
A 1 725 HIS 725 725 725 HIS HIS A . n 
A 1 726 SER 726 726 726 SER SER A . n 
A 1 727 SER 727 727 727 SER SER A . n 
A 1 728 PHE 728 728 728 PHE PHE A . n 
A 1 729 GLU 729 729 729 GLU GLU A . n 
A 1 730 HIS 730 730 730 HIS HIS A . n 
A 1 731 VAL 731 731 731 VAL VAL A . n 
A 1 732 ASP 732 732 732 ASP ASP A . n 
A 1 733 TYR 733 733 733 TYR TYR A . n 
A 1 734 ARG 734 734 734 ARG ARG A . n 
A 1 735 VAL 735 735 735 VAL VAL A . n 
A 1 736 THR 736 736 736 THR THR A . n 
A 1 737 GLY 737 737 737 GLY GLY A . n 
A 1 738 LEU 738 738 738 LEU LEU A . n 
A 1 739 PHE 739 739 739 PHE PHE A . n 
A 1 740 LEU 740 740 740 LEU LEU A . n 
A 1 741 ALA 741 741 741 ALA ALA A . n 
A 1 742 ALA 742 742 742 ALA ALA A . n 
A 1 743 LEU 743 743 743 LEU LEU A . n 
A 1 744 GLU 744 744 744 GLU GLU A . n 
A 1 745 VAL 745 745 745 VAL VAL A . n 
A 1 746 ILE 746 746 746 ILE ILE A . n 
A 1 747 ARG 747 747 747 ARG ARG A . n 
A 1 748 ARG 748 748 748 ARG ARG A . n 
A 1 749 GLY 749 749 749 GLY GLY A . n 
A 1 750 GLN 750 750 750 GLN GLN A . n 
A 1 751 TRP 751 751 751 TRP TRP A . n 
A 1 752 ASN 752 752 752 ASN ASN A . n 
A 1 753 PHE 753 753 753 PHE PHE A . n 
A 1 754 TYR 754 754 754 TYR TYR A . n 
A 1 755 ARG 755 755 755 ARG ARG A . n 
A 1 756 LEU 756 756 756 LEU LEU A . n 
A 1 757 GLU 757 757 757 GLU GLU A . n 
A 1 758 ASN 758 758 758 ASN ASN A . n 
A 1 759 GLU 759 759 759 GLU GLU A . n 
A 1 760 HIS 760 760 760 HIS HIS A . n 
A 1 761 LEU 761 761 761 LEU LEU A . n 
A 1 762 ASN 762 762 762 ASN ASN A . n 
A 1 763 ASN 763 763 763 ASN ASN A . n 
A 1 764 ALA 764 764 764 ALA ALA A . n 
A 1 765 GLY 765 765 765 GLY GLY A . n 
A 1 766 LYS 766 766 766 LYS LYS A . n 
A 1 767 PHE 767 767 767 PHE PHE A . n 
A 1 768 ARG 768 768 768 ARG ARG A . n 
A 1 769 ALA 769 769 769 ALA ALA A . n 
A 1 770 VAL 770 770 770 VAL VAL A . n 
A 1 771 LYS 771 771 771 LYS LYS A . n 
A 1 772 THR 772 772 772 THR THR A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   VAL 2   2   ?   ?   ?   B . n 
B 1 3   LYS 3   3   ?   ?   ?   B . n 
B 1 4   PHE 4   4   ?   ?   ?   B . n 
B 1 5   THR 5   5   ?   ?   ?   B . n 
B 1 6   LYS 6   6   ?   ?   ?   B . n 
B 1 7   GLN 7   7   ?   ?   ?   B . n 
B 1 8   PHE 8   8   ?   ?   ?   B . n 
B 1 9   GLU 9   9   ?   ?   ?   B . n 
B 1 10  GLY 10  10  ?   ?   ?   B . n 
B 1 11  GLN 11  11  11  GLN GLN B . n 
B 1 12  LEU 12  12  12  LEU LEU B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  PRO 14  14  14  PRO PRO B . n 
B 1 15  GLU 15  15  15  GLU GLU B . n 
B 1 16  TRP 16  16  16  TRP TRP B . n 
B 1 17  LYS 17  17  17  LYS LYS B . n 
B 1 18  ASP 18  18  18  ASP ASP B . n 
B 1 19  ALA 19  19  19  ALA ALA B . n 
B 1 20  PHE 20  20  20  PHE PHE B . n 
B 1 21  VAL 21  21  21  VAL VAL B . n 
B 1 22  ASP 22  22  22  ASP ASP B . n 
B 1 23  TYR 23  23  23  TYR TYR B . n 
B 1 24  SER 24  24  24  SER SER B . n 
B 1 25  GLN 25  25  25  GLN GLN B . n 
B 1 26  LEU 26  26  26  LEU LEU B . n 
B 1 27  LYS 27  27  27  LYS LYS B . n 
B 1 28  LYS 28  28  28  LYS LYS B . n 
B 1 29  ASP 29  29  29  ASP ASP B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  LYS 31  31  31  LYS LYS B . n 
B 1 32  LYS 32  32  32  LYS LYS B . n 
B 1 33  ILE 33  33  33  ILE ILE B . n 
B 1 34  HIS 34  34  34  HIS HIS B . n 
B 1 35  LEU 35  35  35  LEU LEU B . n 
B 1 36  PHE 36  36  36  PHE PHE B . n 
B 1 37  THR 37  37  37  THR THR B . n 
B 1 38  ASN 38  38  38  ASN ASN B . n 
B 1 39  GLY 39  39  39  GLY GLY B . n 
B 1 40  VAL 40  40  ?   ?   ?   B . n 
B 1 41  GLU 41  41  ?   ?   ?   B . n 
B 1 42  LYS 42  42  ?   ?   ?   B . n 
B 1 43  LYS 43  43  ?   ?   ?   B . n 
B 1 44  HIS 44  44  ?   ?   ?   B . n 
B 1 45  THR 45  45  ?   ?   ?   B . n 
B 1 46  GLU 46  46  ?   ?   ?   B . n 
B 1 47  THR 47  47  ?   ?   ?   B . n 
B 1 48  SER 48  48  ?   ?   ?   B . n 
B 1 49  LEU 49  49  ?   ?   ?   B . n 
B 1 50  ILE 50  50  ?   ?   ?   B . n 
B 1 51  LYS 51  51  ?   ?   ?   B . n 
B 1 52  THR 52  52  ?   ?   ?   B . n 
B 1 53  VAL 53  53  ?   ?   ?   B . n 
B 1 54  LYS 54  54  ?   ?   ?   B . n 
B 1 55  SER 55  55  ?   ?   ?   B . n 
B 1 56  SER 56  56  ?   ?   ?   B . n 
B 1 57  LEU 57  57  ?   ?   ?   B . n 
B 1 58  GLY 58  58  ?   ?   ?   B . n 
B 1 59  ARG 59  59  ?   ?   ?   B . n 
B 1 60  LEU 60  60  ?   ?   ?   B . n 
B 1 61  SER 61  61  ?   ?   ?   B . n 
B 1 62  ILE 62  62  ?   ?   ?   B . n 
B 1 63  PHE 63  63  ?   ?   ?   B . n 
B 1 64  GLY 64  64  ?   ?   ?   B . n 
B 1 65  ASN 65  65  ?   ?   ?   B . n 
B 1 66  LYS 66  66  ?   ?   ?   B . n 
B 1 67  GLY 67  67  ?   ?   ?   B . n 
B 1 68  ARG 68  68  ?   ?   ?   B . n 
B 1 69  GLU 69  69  ?   ?   ?   B . n 
B 1 70  GLN 70  70  ?   ?   ?   B . n 
B 1 71  SER 71  71  ?   ?   ?   B . n 
B 1 72  ARG 72  72  ?   ?   ?   B . n 
B 1 73  VAL 73  73  73  VAL VAL B . n 
B 1 74  ILE 74  74  74  ILE ILE B . n 
B 1 75  GLN 75  75  75  GLN GLN B . n 
B 1 76  VAL 76  76  76  VAL VAL B . n 
B 1 77  HIS 77  77  77  HIS HIS B . n 
B 1 78  LYS 78  78  78  LYS LYS B . n 
B 1 79  LYS 79  79  79  LYS LYS B . n 
B 1 80  LEU 80  80  80  LEU LEU B . n 
B 1 81  ALA 81  81  81  ALA ALA B . n 
B 1 82  SER 82  82  82  SER SER B . n 
B 1 83  SER 83  83  83  SER SER B . n 
B 1 84  GLY 84  84  84  GLY GLY B . n 
B 1 85  SER 85  85  85  SER SER B . n 
B 1 86  ASN 86  86  86  ASN ASN B . n 
B 1 87  ASN 87  87  87  ASN ASN B . n 
B 1 88  ASP 88  88  88  ASP ASP B . n 
B 1 89  VAL 89  89  89  VAL VAL B . n 
B 1 90  TYR 90  90  90  TYR TYR B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  THR 92  92  92  THR THR B . n 
B 1 93  GLU 93  93  93  GLU GLU B . n 
B 1 94  LEU 94  94  94  LEU LEU B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  GLU 96  96  96  GLU GLU B . n 
B 1 97  LYS 97  97  97  LYS LYS B . n 
B 1 98  ILE 98  98  98  ILE ILE B . n 
B 1 99  ALA 99  99  99  ALA ALA B . n 
B 1 100 ASP 100 100 100 ASP ASP B . n 
B 1 101 ASP 101 101 101 ASP ASP B . n 
B 1 102 THR 102 102 102 THR THR B . n 
B 1 103 ASP 103 103 103 ASP ASP B . n 
B 1 104 ALA 104 104 104 ALA ALA B . n 
B 1 105 ALA 105 105 105 ALA ALA B . n 
B 1 106 LYS 106 106 106 LYS LYS B . n 
B 1 107 GLU 107 107 107 GLU GLU B . n 
B 1 108 PHE 108 108 108 PHE PHE B . n 
B 1 109 PHE 109 109 109 PHE PHE B . n 
B 1 110 ALA 110 110 110 ALA ALA B . n 
B 1 111 CYS 111 111 111 CYS CYS B . n 
B 1 112 LEU 112 112 112 LEU LEU B . n 
B 1 113 ASP 113 113 113 ASP ASP B . n 
B 1 114 MET 114 114 114 MET MET B . n 
B 1 115 GLN 115 115 115 GLN GLN B . n 
B 1 116 LEU 116 116 116 LEU LEU B . n 
B 1 117 ASN 117 117 117 ASN ASN B . n 
B 1 118 LYS 118 118 118 LYS LYS B . n 
B 1 119 VAL 119 119 119 VAL VAL B . n 
B 1 120 ASN 120 120 120 ASN ASN B . n 
B 1 121 GLN 121 121 121 GLN GLN B . n 
B 1 122 PHE 122 122 122 PHE PHE B . n 
B 1 123 TYR 123 123 123 TYR TYR B . n 
B 1 124 LYS 124 124 124 LYS LYS B . n 
B 1 125 THR 125 125 125 THR THR B . n 
B 1 126 LYS 126 126 126 LYS LYS B . n 
B 1 127 GLU 127 127 127 GLU GLU B . n 
B 1 128 LYS 128 128 128 LYS LYS B . n 
B 1 129 GLU 129 129 129 GLU GLU B . n 
B 1 130 PHE 130 130 130 PHE PHE B . n 
B 1 131 LEU 131 131 131 LEU LEU B . n 
B 1 132 GLU 132 132 132 GLU GLU B . n 
B 1 133 ARG 133 133 133 ARG ARG B . n 
B 1 134 GLY 134 134 134 GLY GLY B . n 
B 1 135 GLU 135 135 135 GLU GLU B . n 
B 1 136 CYS 136 136 136 CYS CYS B . n 
B 1 137 LEU 137 137 137 LEU LEU B . n 
B 1 138 LYS 138 138 138 LYS LYS B . n 
B 1 139 LYS 139 139 139 LYS LYS B . n 
B 1 140 GLN 140 140 140 GLN GLN B . n 
B 1 141 MET 141 141 141 MET MET B . n 
B 1 142 ASP 142 142 142 ASP ASP B . n 
B 1 143 ILE 143 143 143 ILE ILE B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 ILE 145 145 145 ILE ILE B . n 
B 1 146 GLU 146 146 146 GLU GLU B . n 
B 1 147 LEU 147 147 147 LEU LEU B . n 
B 1 148 LYS 148 148 148 LYS LYS B . n 
B 1 149 ASP 149 149 149 ASP ASP B . n 
B 1 150 ALA 150 150 150 ALA ALA B . n 
B 1 151 PHE 151 151 151 PHE PHE B . n 
B 1 152 LYS 152 152 152 LYS LYS B . n 
B 1 153 GLN 153 153 153 GLN GLN B . n 
B 1 154 LYS 154 154 154 LYS LYS B . n 
B 1 155 GLN 155 155 155 GLN GLN B . n 
B 1 156 ALA 156 156 156 ALA ALA B . n 
B 1 157 ASN 157 157 157 ASN ASN B . n 
B 1 158 GLY 158 158 ?   ?   ?   B . n 
B 1 159 GLU 159 159 ?   ?   ?   B . n 
B 1 160 SER 160 160 ?   ?   ?   B . n 
B 1 161 THR 161 161 ?   ?   ?   B . n 
B 1 162 GLN 162 162 ?   ?   ?   B . n 
B 1 163 GLU 163 163 ?   ?   ?   B . n 
B 1 164 SER 164 164 ?   ?   ?   B . n 
B 1 165 LYS 165 165 ?   ?   ?   B . n 
B 1 166 GLU 166 166 ?   ?   ?   B . n 
B 1 167 ASP 167 167 ?   ?   ?   B . n 
B 1 168 ASP 168 168 ?   ?   ?   B . n 
B 1 169 SER 169 169 ?   ?   ?   B . n 
B 1 170 ILE 170 170 ?   ?   ?   B . n 
B 1 171 SER 171 171 ?   ?   ?   B . n 
B 1 172 CYS 172 172 ?   ?   ?   B . n 
B 1 173 THR 173 173 ?   ?   ?   B . n 
B 1 174 ILE 174 174 ?   ?   ?   B . n 
B 1 175 SER 175 175 ?   ?   ?   B . n 
B 1 176 CYS 176 176 ?   ?   ?   B . n 
B 1 177 GLU 177 177 ?   ?   ?   B . n 
B 1 178 TYR 178 178 ?   ?   ?   B . n 
B 1 179 ASP 179 179 ?   ?   ?   B . n 
B 1 180 SER 180 180 ?   ?   ?   B . n 
B 1 181 VAL 181 181 ?   ?   ?   B . n 
B 1 182 ARG 182 182 ?   ?   ?   B . n 
B 1 183 GLY 183 183 ?   ?   ?   B . n 
B 1 184 ARG 184 184 ?   ?   ?   B . n 
B 1 185 THR 185 185 ?   ?   ?   B . n 
B 1 186 GLU 186 186 ?   ?   ?   B . n 
B 1 187 GLU 187 187 ?   ?   ?   B . n 
B 1 188 MET 188 188 ?   ?   ?   B . n 
B 1 189 GLN 189 189 ?   ?   ?   B . n 
B 1 190 LEU 190 190 ?   ?   ?   B . n 
B 1 191 GLN 191 191 ?   ?   ?   B . n 
B 1 192 VAL 192 192 ?   ?   ?   B . n 
B 1 193 SER 193 193 ?   ?   ?   B . n 
B 1 194 CYS 194 194 ?   ?   ?   B . n 
B 1 195 LEU 195 195 ?   ?   ?   B . n 
B 1 196 ASP 196 196 ?   ?   ?   B . n 
B 1 197 ASN 197 197 ?   ?   ?   B . n 
B 1 198 LEU 198 198 ?   ?   ?   B . n 
B 1 199 GLU 199 199 ?   ?   ?   B . n 
B 1 200 ASP 200 200 ?   ?   ?   B . n 
B 1 201 ASN 201 201 ?   ?   ?   B . n 
B 1 202 GLY 202 202 ?   ?   ?   B . n 
B 1 203 GLU 203 203 ?   ?   ?   B . n 
B 1 204 GLU 204 204 ?   ?   ?   B . n 
B 1 205 ALA 205 205 ?   ?   ?   B . n 
B 1 206 LEU 206 206 ?   ?   ?   B . n 
B 1 207 GLU 207 207 ?   ?   ?   B . n 
B 1 208 SER 208 208 ?   ?   ?   B . n 
B 1 209 LEU 209 209 ?   ?   ?   B . n 
B 1 210 GLY 210 210 ?   ?   ?   B . n 
B 1 211 SER 211 211 ?   ?   ?   B . n 
B 1 212 GLU 212 212 ?   ?   ?   B . n 
B 1 213 GLU 213 213 ?   ?   ?   B . n 
B 1 214 PRO 214 214 ?   ?   ?   B . n 
B 1 215 ILE 215 215 ?   ?   ?   B . n 
B 1 216 LYS 216 216 ?   ?   ?   B . n 
B 1 217 ALA 217 217 ?   ?   ?   B . n 
B 1 218 ASN 218 218 ?   ?   ?   B . n 
B 1 219 ASN 219 219 ?   ?   ?   B . n 
B 1 220 GLU 220 220 ?   ?   ?   B . n 
B 1 221 ASP 221 221 ?   ?   ?   B . n 
B 1 222 SER 222 222 ?   ?   ?   B . n 
B 1 223 LYS 223 223 ?   ?   ?   B . n 
B 1 224 LEU 224 224 ?   ?   ?   B . n 
B 1 225 THR 225 225 ?   ?   ?   B . n 
B 1 226 THR 226 226 ?   ?   ?   B . n 
B 1 227 VAL 227 227 ?   ?   ?   B . n 
B 1 228 SER 228 228 ?   ?   ?   B . n 
B 1 229 SER 229 229 ?   ?   ?   B . n 
B 1 230 ARG 230 230 ?   ?   ?   B . n 
B 1 231 VAL 231 231 ?   ?   ?   B . n 
B 1 232 PHE 232 232 ?   ?   ?   B . n 
B 1 233 SER 233 233 ?   ?   ?   B . n 
B 1 234 CYS 234 234 ?   ?   ?   B . n 
B 1 235 GLN 235 235 ?   ?   ?   B . n 
B 1 236 GLY 236 236 ?   ?   ?   B . n 
B 1 237 LYS 237 237 ?   ?   ?   B . n 
B 1 238 ASN 238 238 ?   ?   ?   B . n 
B 1 239 VAL 239 239 ?   ?   ?   B . n 
B 1 240 LYS 240 240 ?   ?   ?   B . n 
B 1 241 ILE 241 241 ?   ?   ?   B . n 
B 1 242 LYS 242 242 ?   ?   ?   B . n 
B 1 243 ILE 243 243 ?   ?   ?   B . n 
B 1 244 PRO 244 244 ?   ?   ?   B . n 
B 1 245 LEU 245 245 ?   ?   ?   B . n 
B 1 246 THR 246 246 ?   ?   ?   B . n 
B 1 247 ASN 247 247 ?   ?   ?   B . n 
B 1 248 PRO 248 248 ?   ?   ?   B . n 
B 1 249 SER 249 249 ?   ?   ?   B . n 
B 1 250 ARG 250 250 ?   ?   ?   B . n 
B 1 251 THR 251 251 ?   ?   ?   B . n 
B 1 252 PHE 252 252 ?   ?   ?   B . n 
B 1 253 SER 253 253 ?   ?   ?   B . n 
B 1 254 ALA 254 254 ?   ?   ?   B . n 
B 1 255 ILE 255 255 ?   ?   ?   B . n 
B 1 256 SER 256 256 ?   ?   ?   B . n 
B 1 257 TYR 257 257 ?   ?   ?   B . n 
B 1 258 LEU 258 258 ?   ?   ?   B . n 
B 1 259 ILE 259 259 ?   ?   ?   B . n 
B 1 260 ASN 260 260 ?   ?   ?   B . n 
B 1 261 GLN 261 261 ?   ?   ?   B . n 
B 1 262 SER 262 262 ?   ?   ?   B . n 
B 1 263 SER 263 263 ?   ?   ?   B . n 
B 1 264 SER 264 264 ?   ?   ?   B . n 
B 1 265 LYS 265 265 ?   ?   ?   B . n 
B 1 266 LYS 266 266 ?   ?   ?   B . n 
B 1 267 ASN 267 267 ?   ?   ?   B . n 
B 1 268 GLY 268 268 ?   ?   ?   B . n 
B 1 269 PRO 269 269 ?   ?   ?   B . n 
B 1 270 ASP 270 270 ?   ?   ?   B . n 
B 1 271 GLY 271 271 ?   ?   ?   B . n 
B 1 272 GLY 272 272 ?   ?   ?   B . n 
B 1 273 ASN 273 273 ?   ?   ?   B . n 
B 1 274 LYS 274 274 ?   ?   ?   B . n 
B 1 275 LEU 275 275 ?   ?   ?   B . n 
B 1 276 GLN 276 276 ?   ?   ?   B . n 
B 1 277 ILE 277 277 ?   ?   ?   B . n 
B 1 278 SER 278 278 ?   ?   ?   B . n 
B 1 279 LYS 279 279 ?   ?   ?   B . n 
B 1 280 LYS 280 280 280 LYS LYS B . n 
B 1 281 LYS 281 281 281 LYS LYS B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 SER 283 283 283 SER SER B . n 
B 1 284 HIS 284 284 284 HIS HIS B . n 
B 1 285 ALA 285 285 285 ALA ALA B . n 
B 1 286 GLU 286 286 286 GLU GLU B . n 
B 1 287 LYS 287 287 287 LYS LYS B . n 
B 1 288 MET 288 288 288 MET MET B . n 
B 1 289 ILE 289 289 289 ILE ILE B . n 
B 1 290 LYS 290 290 290 LYS LYS B . n 
B 1 291 GLY 291 291 291 GLY GLY B . n 
B 1 292 ALA 292 292 292 ALA ALA B . n 
B 1 293 LEU 293 293 293 LEU LEU B . n 
B 1 294 THR 294 294 294 THR THR B . n 
B 1 295 GLU 295 295 295 GLU GLU B . n 
B 1 296 LEU 296 296 296 LEU LEU B . n 
B 1 297 PHE 297 297 297 PHE PHE B . n 
B 1 298 LYS 298 298 298 LYS LYS B . n 
B 1 299 GLY 299 299 299 GLY GLY B . n 
B 1 300 LEU 300 300 300 LEU LEU B . n 
B 1 301 ASN 301 301 301 ASN ASN B . n 
B 1 302 TYR 302 302 302 TYR TYR B . n 
B 1 303 LEU 303 303 303 LEU LEU B . n 
B 1 304 LYS 304 304 304 LYS LYS B . n 
B 1 305 THR 305 305 305 THR THR B . n 
B 1 306 TYR 306 306 306 TYR TYR B . n 
B 1 307 ARG 307 307 307 ARG ARG B . n 
B 1 308 ASN 308 308 308 ASN ASN B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 ASN 310 310 310 ASN ASN B . n 
B 1 311 ILE 311 311 311 ILE ILE B . n 
B 1 312 LEU 312 312 312 LEU LEU B . n 
B 1 313 ALA 313 313 313 ALA ALA B . n 
B 1 314 PHE 314 314 314 PHE PHE B . n 
B 1 315 MET 315 315 315 MET MET B . n 
B 1 316 ASN 316 316 316 ASN ASN B . n 
B 1 317 ILE 317 317 317 ILE ILE B . n 
B 1 318 LEU 318 318 318 LEU LEU B . n 
B 1 319 LYS 319 319 319 LYS LYS B . n 
B 1 320 LYS 320 320 320 LYS LYS B . n 
B 1 321 PHE 321 321 321 PHE PHE B . n 
B 1 322 ASP 322 322 322 ASP ASP B . n 
B 1 323 LYS 323 323 323 LYS LYS B . n 
B 1 324 VAL 324 324 324 VAL VAL B . n 
B 1 325 THR 325 325 325 THR THR B . n 
B 1 326 GLY 326 326 326 GLY GLY B . n 
B 1 327 LYS 327 327 327 LYS LYS B . n 
B 1 328 GLN 328 328 328 GLN GLN B . n 
B 1 329 ILE 329 329 329 ILE ILE B . n 
B 1 330 LEU 330 330 330 LEU LEU B . n 
B 1 331 PRO 331 331 331 PRO PRO B . n 
B 1 332 ILE 332 332 332 ILE ILE B . n 
B 1 333 TYR 333 333 333 TYR TYR B . n 
B 1 334 LEU 334 334 334 LEU LEU B . n 
B 1 335 LYS 335 335 335 LYS LYS B . n 
B 1 336 VAL 336 336 336 VAL VAL B . n 
B 1 337 VAL 337 337 337 VAL VAL B . n 
B 1 338 GLU 338 338 338 GLU GLU B . n 
B 1 339 SER 339 339 339 SER SER B . n 
B 1 340 SER 340 340 340 SER SER B . n 
B 1 341 TYR 341 341 341 TYR TYR B . n 
B 1 342 PHE 342 342 342 PHE PHE B . n 
B 1 343 ASN 343 343 343 ASN ASN B . n 
B 1 344 ILE 344 344 344 ILE ILE B . n 
B 1 345 SER 345 345 345 SER SER B . n 
B 1 346 ASP 346 346 346 ASP ASP B . n 
B 1 347 LYS 347 347 347 LYS LYS B . n 
B 1 348 VAL 348 348 348 VAL VAL B . n 
B 1 349 MET 349 349 349 MET MET B . n 
B 1 350 ILE 350 350 350 ILE ILE B . n 
B 1 351 LEU 351 351 351 LEU LEU B . n 
B 1 352 SER 352 352 352 SER SER B . n 
B 1 353 ASP 353 353 353 ASP ASP B . n 
B 1 354 GLU 354 354 354 GLU GLU B . n 
B 1 355 VAL 355 355 355 VAL VAL B . n 
B 1 356 GLU 356 356 356 GLU GLU B . n 
B 1 357 GLU 357 357 357 GLU GLU B . n 
B 1 358 TRP 358 358 358 TRP TRP B . n 
B 1 359 PHE 359 359 359 PHE PHE B . n 
B 1 360 ILE 360 360 360 ILE ILE B . n 
B 1 361 LYS 361 361 361 LYS LYS B . n 
B 1 362 HIS 362 362 362 HIS HIS B . n 
B 1 363 LEU 363 363 363 LEU LEU B . n 
B 1 364 ALA 364 364 364 ALA ALA B . n 
B 1 365 GLY 365 365 365 GLY GLY B . n 
B 1 366 GLU 366 366 366 GLU GLU B . n 
B 1 367 ASN 367 367 367 ASN ASN B . n 
B 1 368 ARG 368 368 368 ARG ARG B . n 
B 1 369 ARG 369 369 369 ARG ARG B . n 
B 1 370 LYS 370 370 370 LYS LYS B . n 
B 1 371 ALA 371 371 371 ALA ALA B . n 
B 1 372 MET 372 372 372 MET MET B . n 
B 1 373 LYS 373 373 373 LYS LYS B . n 
B 1 374 TYR 374 374 374 TYR TYR B . n 
B 1 375 LEU 375 375 375 LEU LEU B . n 
B 1 376 LYS 376 376 376 LYS LYS B . n 
B 1 377 PRO 377 377 377 PRO PRO B . n 
B 1 378 HIS 378 378 378 HIS HIS B . n 
B 1 379 HIS 379 379 379 HIS HIS B . n 
B 1 380 ARG 380 380 380 ARG ARG B . n 
B 1 381 LYS 381 381 381 LYS LYS B . n 
B 1 382 GLU 382 382 382 GLU GLU B . n 
B 1 383 SER 383 383 383 SER SER B . n 
B 1 384 HIS 384 384 384 HIS HIS B . n 
B 1 385 SER 385 385 385 SER SER B . n 
B 1 386 VAL 386 386 386 VAL VAL B . n 
B 1 387 THR 387 387 387 THR THR B . n 
B 1 388 PHE 388 388 388 PHE PHE B . n 
B 1 389 PHE 389 389 389 PHE PHE B . n 
B 1 390 ILE 390 390 390 ILE ILE B . n 
B 1 391 GLY 391 391 391 GLY GLY B . n 
B 1 392 LEU 392 392 392 LEU LEU B . n 
B 1 393 PHE 393 393 393 PHE PHE B . n 
B 1 394 THR 394 394 394 THR THR B . n 
B 1 395 GLY 395 395 395 GLY GLY B . n 
B 1 396 CYS 396 396 396 CYS CYS B . n 
B 1 397 PHE 397 397 397 PHE PHE B . n 
B 1 398 VAL 398 398 398 VAL VAL B . n 
B 1 399 ALA 399 399 399 ALA ALA B . n 
B 1 400 LEU 400 400 400 LEU LEU B . n 
B 1 401 LEU 401 401 401 LEU LEU B . n 
B 1 402 ALA 402 402 402 ALA ALA B . n 
B 1 403 GLY 403 403 403 GLY GLY B . n 
B 1 404 TYR 404 404 404 TYR TYR B . n 
B 1 405 ILE 405 405 405 ILE ILE B . n 
B 1 406 ILE 406 406 406 ILE ILE B . n 
B 1 407 VAL 407 407 407 VAL VAL B . n 
B 1 408 ALA 408 408 408 ALA ALA B . n 
B 1 409 HIS 409 409 409 HIS HIS B . n 
B 1 410 LEU 410 410 410 LEU LEU B . n 
B 1 411 THR 411 411 411 THR THR B . n 
B 1 412 GLY 412 412 412 GLY GLY B . n 
B 1 413 MET 413 413 413 MET MET B . n 
B 1 414 TYR 414 414 414 TYR TYR B . n 
B 1 415 ARG 415 415 415 ARG ARG B . n 
B 1 416 GLN 416 416 416 GLN GLN B . n 
B 1 417 HIS 417 417 417 HIS HIS B . n 
B 1 418 SER 418 418 418 SER SER B . n 
B 1 419 ALA 419 419 419 ALA ALA B . n 
B 1 420 ASN 420 420 420 ASN ASN B . n 
B 1 421 THR 421 421 421 THR THR B . n 
B 1 422 PHE 422 422 422 PHE PHE B . n 
B 1 423 TYR 423 423 423 TYR TYR B . n 
B 1 424 MET 424 424 424 MET MET B . n 
B 1 425 GLU 425 425 425 GLU GLU B . n 
B 1 426 THR 426 426 426 THR THR B . n 
B 1 427 ALA 427 427 427 ALA ALA B . n 
B 1 428 TYR 428 428 428 TYR TYR B . n 
B 1 429 PRO 429 429 429 PRO PRO B . n 
B 1 430 VAL 430 430 430 VAL VAL B . n 
B 1 431 LEU 431 431 431 LEU LEU B . n 
B 1 432 SER 432 432 432 SER SER B . n 
B 1 433 MET 433 433 433 MET MET B . n 
B 1 434 PHE 434 434 434 PHE PHE B . n 
B 1 435 GLY 435 435 435 GLY GLY B . n 
B 1 436 LEU 436 436 436 LEU LEU B . n 
B 1 437 LEU 437 437 437 LEU LEU B . n 
B 1 438 PHE 438 438 438 PHE PHE B . n 
B 1 439 LEU 439 439 439 LEU LEU B . n 
B 1 440 HIS 440 440 440 HIS HIS B . n 
B 1 441 LEU 441 441 441 LEU LEU B . n 
B 1 442 PHE 442 442 442 PHE PHE B . n 
B 1 443 LEU 443 443 443 LEU LEU B . n 
B 1 444 TYR 444 444 444 TYR TYR B . n 
B 1 445 GLY 445 445 445 GLY GLY B . n 
B 1 446 CYS 446 446 446 CYS CYS B . n 
B 1 447 ASN 447 447 447 ASN ASN B . n 
B 1 448 ILE 448 448 448 ILE ILE B . n 
B 1 449 PHE 449 449 449 PHE PHE B . n 
B 1 450 MET 450 450 450 MET MET B . n 
B 1 451 TRP 451 451 451 TRP TRP B . n 
B 1 452 ARG 452 452 452 ARG ARG B . n 
B 1 453 LYS 453 453 453 LYS LYS B . n 
B 1 454 ALA 454 454 454 ALA ALA B . n 
B 1 455 ARG 455 455 455 ARG ARG B . n 
B 1 456 ILE 456 456 456 ILE ILE B . n 
B 1 457 ASN 457 457 457 ASN ASN B . n 
B 1 458 TYR 458 458 458 TYR TYR B . n 
B 1 459 SER 459 459 459 SER SER B . n 
B 1 460 PHE 460 460 460 PHE PHE B . n 
B 1 461 ILE 461 461 461 ILE ILE B . n 
B 1 462 PHE 462 462 462 PHE PHE B . n 
B 1 463 GLU 463 463 463 GLU GLU B . n 
B 1 464 LEU 464 464 464 LEU LEU B . n 
B 1 465 GLY 465 465 465 GLY GLY B . n 
B 1 466 SER 466 466 466 SER SER B . n 
B 1 467 LYS 467 467 467 LYS LYS B . n 
B 1 468 ASN 468 468 468 ASN ASN B . n 
B 1 469 GLU 469 469 469 GLU GLU B . n 
B 1 470 LEU 470 470 470 LEU LEU B . n 
B 1 471 LYS 471 471 471 LYS LYS B . n 
B 1 472 TYR 472 472 472 TYR TYR B . n 
B 1 473 ARG 473 473 473 ARG ARG B . n 
B 1 474 ASP 474 474 474 ASP ASP B . n 
B 1 475 VAL 475 475 475 VAL VAL B . n 
B 1 476 PHE 476 476 476 PHE PHE B . n 
B 1 477 LEU 477 477 477 LEU LEU B . n 
B 1 478 ILE 478 478 478 ILE ILE B . n 
B 1 479 CYS 479 479 479 CYS CYS B . n 
B 1 480 THR 480 480 480 THR THR B . n 
B 1 481 ALA 481 481 481 ALA ALA B . n 
B 1 482 SER 482 482 482 SER SER B . n 
B 1 483 MET 483 483 483 MET MET B . n 
B 1 484 SER 484 484 484 SER SER B . n 
B 1 485 ALA 485 485 485 ALA ALA B . n 
B 1 486 ILE 486 486 486 ILE ILE B . n 
B 1 487 ALA 487 487 487 ALA ALA B . n 
B 1 488 GLY 488 488 488 GLY GLY B . n 
B 1 489 VAL 489 489 489 VAL VAL B . n 
B 1 490 MET 490 490 490 MET MET B . n 
B 1 491 PHE 491 491 491 PHE PHE B . n 
B 1 492 VAL 492 492 492 VAL VAL B . n 
B 1 493 HIS 493 493 493 HIS HIS B . n 
B 1 494 LEU 494 494 494 LEU LEU B . n 
B 1 495 SER 495 495 495 SER SER B . n 
B 1 496 LEU 496 496 496 LEU LEU B . n 
B 1 497 LEU 497 497 497 LEU LEU B . n 
B 1 498 GLU 498 498 498 GLU GLU B . n 
B 1 499 LYS 499 499 499 LYS LYS B . n 
B 1 500 GLY 500 500 500 GLY GLY B . n 
B 1 501 TYR 501 501 501 TYR TYR B . n 
B 1 502 SER 502 502 502 SER SER B . n 
B 1 503 PHE 503 503 503 PHE PHE B . n 
B 1 504 ARG 504 504 504 ARG ARG B . n 
B 1 505 GLN 505 505 505 GLN GLN B . n 
B 1 506 VAL 506 506 506 VAL VAL B . n 
B 1 507 GLN 507 507 507 GLN GLN B . n 
B 1 508 VAL 508 508 508 VAL VAL B . n 
B 1 509 ILE 509 509 509 ILE ILE B . n 
B 1 510 PRO 510 510 510 PRO PRO B . n 
B 1 511 GLY 511 511 511 GLY GLY B . n 
B 1 512 LEU 512 512 512 LEU LEU B . n 
B 1 513 LEU 513 513 513 LEU LEU B . n 
B 1 514 LEU 514 514 514 LEU LEU B . n 
B 1 515 LEU 515 515 515 LEU LEU B . n 
B 1 516 GLY 516 516 516 GLY GLY B . n 
B 1 517 PHE 517 517 517 PHE PHE B . n 
B 1 518 LEU 518 518 518 LEU LEU B . n 
B 1 519 LEU 519 519 519 LEU LEU B . n 
B 1 520 ILE 520 520 520 ILE ILE B . n 
B 1 521 LEU 521 521 521 LEU LEU B . n 
B 1 522 ILE 522 522 522 ILE ILE B . n 
B 1 523 CYS 523 523 523 CYS CYS B . n 
B 1 524 PRO 524 524 524 PRO PRO B . n 
B 1 525 LEU 525 525 525 LEU LEU B . n 
B 1 526 ASN 526 526 526 ASN ASN B . n 
B 1 527 ILE 527 527 527 ILE ILE B . n 
B 1 528 PHE 528 528 528 PHE PHE B . n 
B 1 529 TYR 529 529 529 TYR TYR B . n 
B 1 530 LYS 530 530 530 LYS LYS B . n 
B 1 531 SER 531 531 531 SER SER B . n 
B 1 532 SER 532 532 532 SER SER B . n 
B 1 533 ARG 533 533 533 ARG ARG B . n 
B 1 534 TYR 534 534 534 TYR TYR B . n 
B 1 535 ARG 535 535 535 ARG ARG B . n 
B 1 536 LEU 536 536 536 LEU LEU B . n 
B 1 537 ILE 537 537 537 ILE ILE B . n 
B 1 538 SER 538 538 538 SER SER B . n 
B 1 539 VAL 539 539 539 VAL VAL B . n 
B 1 540 ILE 540 540 540 ILE ILE B . n 
B 1 541 ARG 541 541 541 ARG ARG B . n 
B 1 542 ASN 542 542 542 ASN ASN B . n 
B 1 543 ILE 543 543 543 ILE ILE B . n 
B 1 544 VAL 544 544 544 VAL VAL B . n 
B 1 545 PHE 545 545 545 PHE PHE B . n 
B 1 546 SER 546 546 546 SER SER B . n 
B 1 547 PRO 547 547 547 PRO PRO B . n 
B 1 548 LEU 548 548 548 LEU LEU B . n 
B 1 549 TYR 549 549 549 TYR TYR B . n 
B 1 550 LYS 550 550 550 LYS LYS B . n 
B 1 551 VAL 551 551 551 VAL VAL B . n 
B 1 552 VAL 552 552 552 VAL VAL B . n 
B 1 553 MET 553 553 553 MET MET B . n 
B 1 554 LEU 554 554 554 LEU LEU B . n 
B 1 555 ASP 555 555 555 ASP ASP B . n 
B 1 556 PHE 556 556 556 PHE PHE B . n 
B 1 557 PHE 557 557 557 PHE PHE B . n 
B 1 558 MET 558 558 558 MET MET B . n 
B 1 559 ALA 559 559 559 ALA ALA B . n 
B 1 560 ASP 560 560 560 ASP ASP B . n 
B 1 561 GLN 561 561 561 GLN GLN B . n 
B 1 562 LEU 562 562 562 LEU LEU B . n 
B 1 563 CYS 563 563 563 CYS CYS B . n 
B 1 564 SER 564 564 564 SER SER B . n 
B 1 565 GLN 565 565 565 GLN GLN B . n 
B 1 566 VAL 566 566 566 VAL VAL B . n 
B 1 567 PRO 567 567 567 PRO PRO B . n 
B 1 568 MET 568 568 568 MET MET B . n 
B 1 569 LEU 569 569 569 LEU LEU B . n 
B 1 570 ARG 570 570 570 ARG ARG B . n 
B 1 571 ASN 571 571 571 ASN ASN B . n 
B 1 572 LEU 572 572 572 LEU LEU B . n 
B 1 573 GLU 573 573 573 GLU GLU B . n 
B 1 574 TYR 574 574 574 TYR TYR B . n 
B 1 575 ILE 575 575 575 ILE ILE B . n 
B 1 576 ALA 576 576 576 ALA ALA B . n 
B 1 577 CYS 577 577 577 CYS CYS B . n 
B 1 578 TYR 578 578 578 TYR TYR B . n 
B 1 579 TYR 579 579 579 TYR TYR B . n 
B 1 580 ILE 580 580 580 ILE ILE B . n 
B 1 581 THR 581 581 581 THR THR B . n 
B 1 582 GLY 582 582 582 GLY GLY B . n 
B 1 583 SER 583 583 583 SER SER B . n 
B 1 584 TYR 584 584 584 TYR TYR B . n 
B 1 585 ALA 585 585 585 ALA ALA B . n 
B 1 586 THR 586 586 586 THR THR B . n 
B 1 587 GLN 587 587 587 GLN GLN B . n 
B 1 588 ASP 588 588 588 ASP ASP B . n 
B 1 589 TYR 589 589 589 TYR TYR B . n 
B 1 590 GLU 590 590 590 GLU GLU B . n 
B 1 591 TYR 591 591 591 TYR TYR B . n 
B 1 592 CYS 592 592 592 CYS CYS B . n 
B 1 593 MET 593 593 593 MET MET B . n 
B 1 594 ARG 594 594 594 ARG ARG B . n 
B 1 595 VAL 595 595 595 VAL VAL B . n 
B 1 596 LYS 596 596 596 LYS LYS B . n 
B 1 597 TYR 597 597 597 TYR TYR B . n 
B 1 598 TYR 598 598 598 TYR TYR B . n 
B 1 599 ARG 599 599 599 ARG ARG B . n 
B 1 600 ASP 600 600 600 ASP ASP B . n 
B 1 601 LEU 601 601 601 LEU LEU B . n 
B 1 602 ALA 602 602 602 ALA ALA B . n 
B 1 603 TYR 603 603 603 TYR TYR B . n 
B 1 604 ALA 604 604 604 ALA ALA B . n 
B 1 605 VAL 605 605 605 VAL VAL B . n 
B 1 606 SER 606 606 606 SER SER B . n 
B 1 607 PHE 607 607 607 PHE PHE B . n 
B 1 608 LEU 608 608 608 LEU LEU B . n 
B 1 609 PRO 609 609 609 PRO PRO B . n 
B 1 610 TYR 610 610 610 TYR TYR B . n 
B 1 611 TYR 611 611 611 TYR TYR B . n 
B 1 612 TRP 612 612 612 TRP TRP B . n 
B 1 613 ARG 613 613 613 ARG ARG B . n 
B 1 614 ALA 614 614 614 ALA ALA B . n 
B 1 615 MET 615 615 615 MET MET B . n 
B 1 616 GLN 616 616 616 GLN GLN B . n 
B 1 617 CYS 617 617 617 CYS CYS B . n 
B 1 618 ALA 618 618 618 ALA ALA B . n 
B 1 619 ARG 619 619 619 ARG ARG B . n 
B 1 620 ARG 620 620 620 ARG ARG B . n 
B 1 621 TRP 621 621 621 TRP TRP B . n 
B 1 622 PHE 622 622 622 PHE PHE B . n 
B 1 623 ASP 623 623 623 ASP ASP B . n 
B 1 624 GLU 624 624 624 GLU GLU B . n 
B 1 625 GLY 625 625 625 GLY GLY B . n 
B 1 626 GLU 626 626 626 GLU GLU B . n 
B 1 627 THR 627 627 627 THR THR B . n 
B 1 628 SER 628 628 628 SER SER B . n 
B 1 629 HIS 629 629 629 HIS HIS B . n 
B 1 630 LEU 630 630 630 LEU LEU B . n 
B 1 631 VAL 631 631 631 VAL VAL B . n 
B 1 632 ASN 632 632 632 ASN ASN B . n 
B 1 633 LEU 633 633 633 LEU LEU B . n 
B 1 634 GLY 634 634 634 GLY GLY B . n 
B 1 635 LYS 635 635 635 LYS LYS B . n 
B 1 636 TYR 636 636 636 TYR TYR B . n 
B 1 637 VAL 637 637 637 VAL VAL B . n 
B 1 638 SER 638 638 638 SER SER B . n 
B 1 639 ALA 639 639 639 ALA ALA B . n 
B 1 640 MET 640 640 640 MET MET B . n 
B 1 641 LEU 641 641 641 LEU LEU B . n 
B 1 642 ALA 642 642 642 ALA ALA B . n 
B 1 643 ALA 643 643 643 ALA ALA B . n 
B 1 644 GLY 644 644 644 GLY GLY B . n 
B 1 645 THR 645 645 645 THR THR B . n 
B 1 646 LYS 646 646 646 LYS LYS B . n 
B 1 647 VAL 647 647 647 VAL VAL B . n 
B 1 648 ALA 648 648 648 ALA ALA B . n 
B 1 649 TYR 649 649 649 TYR TYR B . n 
B 1 650 GLU 650 650 650 GLU GLU B . n 
B 1 651 LYS 651 651 651 LYS LYS B . n 
B 1 652 GLU 652 652 652 GLU GLU B . n 
B 1 653 ARG 653 653 653 ARG ARG B . n 
B 1 654 SER 654 654 654 SER SER B . n 
B 1 655 LEU 655 655 655 LEU LEU B . n 
B 1 656 GLY 656 656 656 GLY GLY B . n 
B 1 657 TRP 657 657 657 TRP TRP B . n 
B 1 658 LEU 658 658 658 LEU LEU B . n 
B 1 659 CYS 659 659 659 CYS CYS B . n 
B 1 660 LEU 660 660 660 LEU LEU B . n 
B 1 661 VAL 661 661 661 VAL VAL B . n 
B 1 662 VAL 662 662 662 VAL VAL B . n 
B 1 663 ALA 663 663 663 ALA ALA B . n 
B 1 664 MET 664 664 664 MET MET B . n 
B 1 665 SER 665 665 665 SER SER B . n 
B 1 666 SER 666 666 666 SER SER B . n 
B 1 667 VAL 667 667 667 VAL VAL B . n 
B 1 668 ALA 668 668 668 ALA ALA B . n 
B 1 669 THR 669 669 669 THR THR B . n 
B 1 670 ILE 670 670 670 ILE ILE B . n 
B 1 671 TYR 671 671 671 TYR TYR B . n 
B 1 672 GLN 672 672 672 GLN GLN B . n 
B 1 673 LEU 673 673 673 LEU LEU B . n 
B 1 674 TYR 674 674 674 TYR TYR B . n 
B 1 675 TRP 675 675 675 TRP TRP B . n 
B 1 676 ASP 676 676 676 ASP ASP B . n 
B 1 677 PHE 677 677 677 PHE PHE B . n 
B 1 678 VAL 678 678 678 VAL VAL B . n 
B 1 679 LYS 679 679 679 LYS LYS B . n 
B 1 680 ASP 680 680 680 ASP ASP B . n 
B 1 681 TRP 681 681 681 TRP TRP B . n 
B 1 682 GLY 682 682 682 GLY GLY B . n 
B 1 683 LEU 683 683 683 LEU LEU B . n 
B 1 684 LEU 684 684 684 LEU LEU B . n 
B 1 685 GLN 685 685 685 GLN GLN B . n 
B 1 686 HIS 686 686 686 HIS HIS B . n 
B 1 687 ASN 687 687 687 ASN ASN B . n 
B 1 688 SER 688 688 688 SER SER B . n 
B 1 689 ASN 689 689 689 ASN ASN B . n 
B 1 690 ASN 690 690 690 ASN ASN B . n 
B 1 691 PRO 691 691 691 PRO PRO B . n 
B 1 692 TRP 692 692 692 TRP TRP B . n 
B 1 693 LEU 693 693 693 LEU LEU B . n 
B 1 694 ARG 694 694 694 ARG ARG B . n 
B 1 695 ASN 695 695 695 ASN ASN B . n 
B 1 696 GLN 696 696 696 GLN GLN B . n 
B 1 697 LEU 697 697 697 LEU LEU B . n 
B 1 698 MET 698 698 698 MET MET B . n 
B 1 699 LEU 699 699 699 LEU LEU B . n 
B 1 700 ARG 700 700 700 ARG ARG B . n 
B 1 701 GLN 701 701 701 GLN GLN B . n 
B 1 702 LYS 702 702 702 LYS LYS B . n 
B 1 703 SER 703 703 703 SER SER B . n 
B 1 704 ILE 704 704 704 ILE ILE B . n 
B 1 705 TYR 705 705 705 TYR TYR B . n 
B 1 706 TYR 706 706 706 TYR TYR B . n 
B 1 707 PHE 707 707 707 PHE PHE B . n 
B 1 708 SER 708 708 708 SER SER B . n 
B 1 709 MET 709 709 709 MET MET B . n 
B 1 710 VAL 710 710 710 VAL VAL B . n 
B 1 711 LEU 711 711 711 LEU LEU B . n 
B 1 712 ASN 712 712 712 ASN ASN B . n 
B 1 713 LEU 713 713 713 LEU LEU B . n 
B 1 714 VAL 714 714 714 VAL VAL B . n 
B 1 715 LEU 715 715 715 LEU LEU B . n 
B 1 716 ARG 716 716 716 ARG ARG B . n 
B 1 717 LEU 717 717 717 LEU LEU B . n 
B 1 718 ALA 718 718 718 ALA ALA B . n 
B 1 719 TRP 719 719 719 TRP TRP B . n 
B 1 720 LEU 720 720 720 LEU LEU B . n 
B 1 721 GLN 721 721 721 GLN GLN B . n 
B 1 722 THR 722 722 722 THR THR B . n 
B 1 723 VAL 723 723 723 VAL VAL B . n 
B 1 724 LEU 724 724 724 LEU LEU B . n 
B 1 725 HIS 725 725 725 HIS HIS B . n 
B 1 726 SER 726 726 726 SER SER B . n 
B 1 727 SER 727 727 727 SER SER B . n 
B 1 728 PHE 728 728 728 PHE PHE B . n 
B 1 729 GLU 729 729 729 GLU GLU B . n 
B 1 730 HIS 730 730 730 HIS HIS B . n 
B 1 731 VAL 731 731 731 VAL VAL B . n 
B 1 732 ASP 732 732 732 ASP ASP B . n 
B 1 733 TYR 733 733 733 TYR TYR B . n 
B 1 734 ARG 734 734 734 ARG ARG B . n 
B 1 735 VAL 735 735 735 VAL VAL B . n 
B 1 736 THR 736 736 736 THR THR B . n 
B 1 737 GLY 737 737 737 GLY GLY B . n 
B 1 738 LEU 738 738 738 LEU LEU B . n 
B 1 739 PHE 739 739 739 PHE PHE B . n 
B 1 740 LEU 740 740 740 LEU LEU B . n 
B 1 741 ALA 741 741 741 ALA ALA B . n 
B 1 742 ALA 742 742 742 ALA ALA B . n 
B 1 743 LEU 743 743 743 LEU LEU B . n 
B 1 744 GLU 744 744 744 GLU GLU B . n 
B 1 745 VAL 745 745 745 VAL VAL B . n 
B 1 746 ILE 746 746 746 ILE ILE B . n 
B 1 747 ARG 747 747 747 ARG ARG B . n 
B 1 748 ARG 748 748 748 ARG ARG B . n 
B 1 749 GLY 749 749 749 GLY GLY B . n 
B 1 750 GLN 750 750 750 GLN GLN B . n 
B 1 751 TRP 751 751 751 TRP TRP B . n 
B 1 752 ASN 752 752 752 ASN ASN B . n 
B 1 753 PHE 753 753 753 PHE PHE B . n 
B 1 754 TYR 754 754 754 TYR TYR B . n 
B 1 755 ARG 755 755 755 ARG ARG B . n 
B 1 756 LEU 756 756 756 LEU LEU B . n 
B 1 757 GLU 757 757 757 GLU GLU B . n 
B 1 758 ASN 758 758 758 ASN ASN B . n 
B 1 759 GLU 759 759 759 GLU GLU B . n 
B 1 760 HIS 760 760 760 HIS HIS B . n 
B 1 761 LEU 761 761 761 LEU LEU B . n 
B 1 762 ASN 762 762 762 ASN ASN B . n 
B 1 763 ASN 763 763 763 ASN ASN B . n 
B 1 764 ALA 764 764 764 ALA ALA B . n 
B 1 765 GLY 765 765 765 GLY GLY B . n 
B 1 766 LYS 766 766 766 LYS LYS B . n 
B 1 767 PHE 767 767 767 PHE PHE B . n 
B 1 768 ARG 768 768 768 ARG ARG B . n 
B 1 769 ALA 769 769 769 ALA ALA B . n 
B 1 770 VAL 770 770 770 VAL VAL B . n 
B 1 771 LYS 771 771 771 LYS LYS B . n 
B 1 772 THR 772 772 772 THR THR B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 IHP ? ? IHP ? ? 'SUBJECT OF INVESTIGATION' ? 
2 PO4 ? ? PO4 ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 IHP 1 801  1002 IHP IHP A . 
D 3 PO4 1 802  1001 PO4 PO4 A . 
E 3 PO4 1 1001 1001 PO4 PO4 B . 
F 2 IHP 1 1002 1002 IHP IHP B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9IK4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9IK4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9IK4 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9IK4 
_struct.title                        'Cryo-EM structure of Arabidopsis thaliana phosphate transporter PHO1;H1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9IK4 
_struct_keywords.text            'phosphate transport, SPX domain, SPX-EXS, InsP6, PHO1, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PHO11_ARATH 
_struct_ref.pdbx_db_accession          Q93ZF5 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MVKFTKQFEGQLVPEWKDAFVDYSQLKKDLKKIHLFTNGVEKKHTETSLIKTVKSSLGRLSIFGNKGREQSRVIQVHKKL
ASSGSNNDVYETELLEKIADDTDAAKEFFACLDMQLNKVNQFYKTKEKEFLERGECLKKQMDILIELKDAFKQKQANGES
TQESKEDDSISCTISCEYDSVRGRTEEMQLQVSCLDNLEDNGEEALESLGSEEPIKANNEDSKLTTVSSRVFSCQGKNVK
IKIPLTNPSRTFSAISYLINQSSSKKNGPDGGNKLQISKKKLSHAEKMIKGALTELFKGLNYLKTYRNLNILAFMNILKK
FDKVTGKQILPIYLKVVESSYFNISDKVMILSDEVEEWFIKHLAGENRRKAMKYLKPHHRKESHSVTFFIGLFTGCFVAL
LAGYIIVAHLTGMYRQHSANTFYMETAYPVLSMFGLLFLHLFLYGCNIFMWRKARINYSFIFELGSKNELKYRDVFLICT
ASMSAIAGVMFVHLSLLEKGYSFRQVQVIPGLLLLGFLLILICPLNIFYKSSRYRLISVIRNIVFSPLYKVVMLDFFMAD
QLCSQVPMLRNLEYIACYYITGSYATQDYEYCMRVKYYRDLAYAVSFLPYYWRAMQCARRWFDEGETSHLVNLGKYVSAM
LAAGTKVAYEKERSLGWLCLVVAMSSVATIYQLYWDFVKDWGLLQHNSNNPWLRNQLMLRQKSIYYFSMVLNLVLRLAWL
QTVLHSSFEHVDYRVTGLFLAALEVIRRGQWNFYRLENEHLNNAGKFRAVKT
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9IK4 A 1 ? 772 ? Q93ZF5 1 ? 772 ? 1 772 
2 1 9IK4 B 1 ? 772 ? Q93ZF5 1 ? 772 ? 1 772 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 24  ? GLY A 39  ? SER A 24  GLY A 39  1 ? 16 
HELX_P HELX_P2  AA2 ALA A 104 ? PHE A 151 ? ALA A 104 PHE A 151 1 ? 48 
HELX_P HELX_P3  AA3 SER A 283 ? ILE A 317 ? SER A 283 ILE A 317 1 ? 35 
HELX_P HELX_P4  AA4 LYS A 320 ? THR A 325 ? LYS A 320 THR A 325 1 ? 6  
HELX_P HELX_P5  AA5 GLN A 328 ? TYR A 333 ? GLN A 328 TYR A 333 1 ? 6  
HELX_P HELX_P6  AA6 TYR A 333 ? GLU A 338 ? TYR A 333 GLU A 338 1 ? 6  
HELX_P HELX_P7  AA7 SER A 340 ? SER A 345 ? SER A 340 SER A 345 1 ? 6  
HELX_P HELX_P8  AA8 ILE A 350 ? VAL A 355 ? ILE A 350 VAL A 355 1 ? 6  
HELX_P HELX_P9  AA9 ARG A 369 ? TYR A 374 ? ARG A 369 TYR A 374 1 ? 6  
HELX_P HELX_P10 AB1 VAL A 386 ? GLY A 403 ? VAL A 386 GLY A 403 1 ? 18 
HELX_P HELX_P11 AB2 SER A 432 ? TYR A 444 ? SER A 432 TYR A 444 1 ? 13 
HELX_P HELX_P12 AB3 ASN A 447 ? LYS A 453 ? ASN A 447 LYS A 453 1 ? 7  
HELX_P HELX_P13 AB4 ASN A 457 ? PHE A 462 ? ASN A 457 PHE A 462 1 ? 6  
HELX_P HELX_P14 AB5 LEU A 477 ? SER A 482 ? LEU A 477 SER A 482 1 ? 6  
HELX_P HELX_P15 AB6 MET A 483 ? MET A 490 ? MET A 483 MET A 490 1 ? 8  
HELX_P HELX_P16 AB7 PHE A 491 ? GLY A 500 ? PHE A 491 GLY A 500 1 ? 10 
HELX_P HELX_P17 AB8 SER A 502 ? GLN A 507 ? SER A 502 GLN A 507 1 ? 6  
HELX_P HELX_P18 AB9 VAL A 508 ? ILE A 522 ? VAL A 508 ILE A 522 1 ? 15 
HELX_P HELX_P19 AC1 VAL A 552 ? PHE A 557 ? VAL A 552 PHE A 557 1 ? 6  
HELX_P HELX_P20 AC2 MET A 558 ? ASP A 560 ? MET A 558 ASP A 560 5 ? 3  
HELX_P HELX_P21 AC3 PRO A 567 ? ASN A 571 ? PRO A 567 ASN A 571 5 ? 5  
HELX_P HELX_P22 AC4 TYR A 574 ? TYR A 578 ? TYR A 574 TYR A 578 5 ? 5  
HELX_P HELX_P23 AC5 VAL A 595 ? ARG A 599 ? VAL A 595 ARG A 599 5 ? 5  
HELX_P HELX_P24 AC6 LEU A 608 ? MET A 615 ? LEU A 608 MET A 615 1 ? 8  
HELX_P HELX_P25 AC7 THR A 627 ? ALA A 642 ? THR A 627 ALA A 642 1 ? 16 
HELX_P HELX_P26 AC8 ALA A 643 ? ALA A 648 ? ALA A 643 ALA A 648 1 ? 6  
HELX_P HELX_P27 AC9 VAL A 662 ? GLN A 672 ? VAL A 662 GLN A 672 1 ? 11 
HELX_P HELX_P28 AD1 GLN A 672 ? VAL A 678 ? GLN A 672 VAL A 678 1 ? 7  
HELX_P HELX_P29 AD2 SER A 703 ? LEU A 711 ? SER A 703 LEU A 711 1 ? 9  
HELX_P HELX_P30 AD3 LEU A 713 ? LEU A 717 ? LEU A 713 LEU A 717 5 ? 5  
HELX_P HELX_P31 AD4 LEU A 740 ? ARG A 748 ? LEU A 740 ARG A 748 1 ? 9  
HELX_P HELX_P32 AD5 GLN A 750 ? ASN A 762 ? GLN A 750 ASN A 762 1 ? 13 
HELX_P HELX_P33 AD6 SER B 24  ? GLY B 39  ? SER B 24  GLY B 39  1 ? 16 
HELX_P HELX_P34 AD7 ALA B 104 ? PHE B 151 ? ALA B 104 PHE B 151 1 ? 48 
HELX_P HELX_P35 AD8 SER B 283 ? ILE B 317 ? SER B 283 ILE B 317 1 ? 35 
HELX_P HELX_P36 AD9 LYS B 320 ? THR B 325 ? LYS B 320 THR B 325 1 ? 6  
HELX_P HELX_P37 AE1 GLN B 328 ? TYR B 333 ? GLN B 328 TYR B 333 1 ? 6  
HELX_P HELX_P38 AE2 TYR B 333 ? GLU B 338 ? TYR B 333 GLU B 338 1 ? 6  
HELX_P HELX_P39 AE3 SER B 340 ? SER B 345 ? SER B 340 SER B 345 1 ? 6  
HELX_P HELX_P40 AE4 ILE B 350 ? VAL B 355 ? ILE B 350 VAL B 355 1 ? 6  
HELX_P HELX_P41 AE5 ARG B 369 ? TYR B 374 ? ARG B 369 TYR B 374 1 ? 6  
HELX_P HELX_P42 AE6 VAL B 386 ? GLY B 403 ? VAL B 386 GLY B 403 1 ? 18 
HELX_P HELX_P43 AE7 SER B 432 ? TYR B 444 ? SER B 432 TYR B 444 1 ? 13 
HELX_P HELX_P44 AE8 ASN B 447 ? LYS B 453 ? ASN B 447 LYS B 453 1 ? 7  
HELX_P HELX_P45 AE9 ASN B 457 ? PHE B 462 ? ASN B 457 PHE B 462 1 ? 6  
HELX_P HELX_P46 AF1 LEU B 477 ? SER B 482 ? LEU B 477 SER B 482 1 ? 6  
HELX_P HELX_P47 AF2 MET B 483 ? MET B 490 ? MET B 483 MET B 490 1 ? 8  
HELX_P HELX_P48 AF3 PHE B 491 ? GLY B 500 ? PHE B 491 GLY B 500 1 ? 10 
HELX_P HELX_P49 AF4 SER B 502 ? GLN B 507 ? SER B 502 GLN B 507 1 ? 6  
HELX_P HELX_P50 AF5 VAL B 508 ? ILE B 522 ? VAL B 508 ILE B 522 1 ? 15 
HELX_P HELX_P51 AF6 VAL B 552 ? PHE B 557 ? VAL B 552 PHE B 557 1 ? 6  
HELX_P HELX_P52 AF7 MET B 558 ? ASP B 560 ? MET B 558 ASP B 560 5 ? 3  
HELX_P HELX_P53 AF8 PRO B 567 ? ASN B 571 ? PRO B 567 ASN B 571 5 ? 5  
HELX_P HELX_P54 AF9 TYR B 574 ? TYR B 578 ? TYR B 574 TYR B 578 5 ? 5  
HELX_P HELX_P55 AG1 VAL B 595 ? ARG B 599 ? VAL B 595 ARG B 599 5 ? 5  
HELX_P HELX_P56 AG2 LEU B 608 ? MET B 615 ? LEU B 608 MET B 615 1 ? 8  
HELX_P HELX_P57 AG3 THR B 627 ? ALA B 642 ? THR B 627 ALA B 642 1 ? 16 
HELX_P HELX_P58 AG4 ALA B 643 ? ALA B 648 ? ALA B 643 ALA B 648 1 ? 6  
HELX_P HELX_P59 AG5 VAL B 662 ? GLN B 672 ? VAL B 662 GLN B 672 1 ? 11 
HELX_P HELX_P60 AG6 GLN B 672 ? VAL B 678 ? GLN B 672 VAL B 678 1 ? 7  
HELX_P HELX_P61 AG7 SER B 703 ? LEU B 711 ? SER B 703 LEU B 711 1 ? 9  
HELX_P HELX_P62 AG8 LEU B 713 ? LEU B 717 ? LEU B 713 LEU B 717 5 ? 5  
HELX_P HELX_P63 AG9 LEU B 740 ? ARG B 748 ? LEU B 740 ARG B 748 1 ? 9  
HELX_P HELX_P64 AH1 GLN B 750 ? ASN B 762 ? GLN B 750 ASN B 762 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 577 SG ? ? ? 1_555 A CYS 592 SG ? ? A CYS 577 A CYS 592 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf2 disulf ? ? B CYS 577 SG ? ? ? 1_555 B CYS 592 SG ? ? B CYS 577 B CYS 592 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 577 ? CYS A 592 ? CYS A 577 ? 1_555 CYS A 592 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 577 ? CYS B 592 ? CYS B 577 ? 1_555 CYS B 592 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 HIS A 77 ? LYS A 79 ? HIS A 77 LYS A 79 
AA1 2 VAL A 89 ? GLU A 91 ? VAL A 89 GLU A 91 
AA2 1 HIS B 77 ? LYS B 79 ? HIS B 77 LYS B 79 
AA2 2 VAL B 89 ? GLU B 91 ? VAL B 89 GLU B 91 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N HIS A 77 ? N HIS A 77 O GLU A 91 ? O GLU A 91 
AA2 1 2 N HIS B 77 ? N HIS B 77 O GLU B 91 ? O GLU B 91 
# 
_pdbx_entry_details.entry_id                   9IK4 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 CD2 A TYR 733 ? ? CG2 A THR 736  ? ? 1.88 
2 1 CD2 B TYR 733 ? ? CG2 B THR 736  ? ? 1.88 
3 1 CE2 A TYR 733 ? ? CG2 A THR 736  ? ? 1.98 
4 1 CE2 B TYR 733 ? ? CG2 B THR 736  ? ? 1.98 
5 1 CE  B LYS 27  ? ? O36 B IHP 1002 ? ? 2.13 
6 1 CE  A LYS 27  ? ? O36 A IHP 801  ? ? 2.14 
7 1 CE2 A TYR 733 ? ? CB  A THR 736  ? ? 2.19 
8 1 CE2 B TYR 733 ? ? CB  B THR 736  ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA A LEU 410 ? ? CB A LEU 410 ? ? CG A LEU 410 ? ? 131.24 115.30 15.94 2.30 N 
2 1 N  A GLY 412 ? ? CA A GLY 412 ? ? C  A GLY 412 ? ? 137.78 113.10 24.68 2.50 N 
3 1 CA B LEU 410 ? ? CB B LEU 410 ? ? CG B LEU 410 ? ? 131.26 115.30 15.96 2.30 N 
4 1 N  B GLY 412 ? ? CA B GLY 412 ? ? C  B GLY 412 ? ? 137.73 113.10 24.63 2.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 95  ? ? -132.76 -30.60  
2  1 ARG A 133 ? ? -94.22  36.53   
3  1 GLN A 328 ? ? -98.34  33.96   
4  1 LEU A 375 ? ? -143.34 13.98   
5  1 LYS A 381 ? ? -79.80  -168.75 
6  1 HIS A 384 ? ? -88.24  48.91   
7  1 LEU A 410 ? ? -95.48  50.88   
8  1 HIS A 417 ? ? -105.12 40.32   
9  1 SER A 418 ? ? -143.98 -154.88 
10 1 ALA A 419 ? ? -70.58  -166.46 
11 1 PHE A 422 ? ? -84.05  43.91   
12 1 TYR A 423 ? ? -120.75 -54.75  
13 1 PRO A 429 ? ? -88.49  35.29   
14 1 VAL A 430 ? ? -135.07 -56.35  
15 1 ASN A 468 ? ? 58.19   70.74   
16 1 SER A 502 ? ? 64.06   74.67   
17 1 PHE A 503 ? ? -38.19  -32.99  
18 1 GLN A 507 ? ? -96.21  52.56   
19 1 LEU A 525 ? ? -84.27  -85.85  
20 1 ASN A 526 ? ? -158.77 2.41    
21 1 TYR A 549 ? ? 60.67   72.43   
22 1 ALA A 576 ? ? -87.01  48.41   
23 1 PHE A 607 ? ? -93.89  46.85   
24 1 GLU A 624 ? ? 78.66   -12.00  
25 1 HIS A 629 ? ? -93.94  47.34   
26 1 ALA A 639 ? ? -94.12  48.29   
27 1 SER A 654 ? ? -158.08 -159.95 
28 1 LEU A 655 ? ? -89.84  30.72   
29 1 TRP A 657 ? ? -84.80  49.20   
30 1 ARG A 700 ? ? -75.46  -157.02 
31 1 GLN A 701 ? ? -36.80  140.22  
32 1 LEU A 720 ? ? 68.22   -2.63   
33 1 PHE A 728 ? ? -95.23  58.83   
34 1 HIS A 730 ? ? -148.83 -152.78 
35 1 VAL A 731 ? ? -38.17  136.07  
36 1 LEU B 95  ? ? -132.75 -30.65  
37 1 ARG B 133 ? ? -94.18  36.54   
38 1 GLN B 328 ? ? -98.31  33.89   
39 1 LEU B 375 ? ? -143.37 14.07   
40 1 LYS B 381 ? ? -79.71  -168.74 
41 1 HIS B 384 ? ? -88.23  48.89   
42 1 LEU B 410 ? ? -95.51  50.99   
43 1 HIS B 417 ? ? -105.07 40.30   
44 1 SER B 418 ? ? -143.98 -154.83 
45 1 ALA B 419 ? ? -70.63  -166.40 
46 1 PHE B 422 ? ? -84.07  43.93   
47 1 TYR B 423 ? ? -120.79 -54.66  
48 1 ASN B 468 ? ? 58.21   70.77   
49 1 SER B 502 ? ? 64.13   74.65   
50 1 PHE B 503 ? ? -38.24  -32.90  
51 1 GLN B 507 ? ? -96.24  52.62   
52 1 LEU B 525 ? ? -84.29  -85.78  
53 1 ASN B 526 ? ? -158.83 2.44    
54 1 TYR B 549 ? ? 60.72   72.44   
55 1 ALA B 576 ? ? -86.93  48.33   
56 1 PHE B 607 ? ? -93.90  46.82   
57 1 GLU B 624 ? ? 78.03   -11.94  
58 1 HIS B 629 ? ? -93.88  47.32   
59 1 ALA B 639 ? ? -94.08  48.26   
60 1 SER B 654 ? ? -158.10 -159.94 
61 1 LEU B 655 ? ? -89.73  30.62   
62 1 TRP B 657 ? ? -84.81  49.21   
63 1 ARG B 700 ? ? -75.42  -156.98 
64 1 GLN B 701 ? ? -36.79  140.22  
65 1 LEU B 720 ? ? 68.30   -2.62   
66 1 PHE B 728 ? ? -95.22  58.76   
67 1 HIS B 730 ? ? -148.86 -152.80 
68 1 VAL B 731 ? ? -38.10  136.02  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9IK4 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9IK4 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.34 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               375307 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Phosphate transporter PHO1;H1' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9IK4 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             8000 
_em_imaging.nominal_defocus_max             20000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9IK4 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9IK4 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              9IK4 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A VAL 2   ? A VAL 2   
3   1 Y 1 A LYS 3   ? A LYS 3   
4   1 Y 1 A PHE 4   ? A PHE 4   
5   1 Y 1 A THR 5   ? A THR 5   
6   1 Y 1 A LYS 6   ? A LYS 6   
7   1 Y 1 A GLN 7   ? A GLN 7   
8   1 Y 1 A PHE 8   ? A PHE 8   
9   1 Y 1 A GLU 9   ? A GLU 9   
10  1 Y 1 A GLY 10  ? A GLY 10  
11  1 Y 1 A VAL 40  ? A VAL 40  
12  1 Y 1 A GLU 41  ? A GLU 41  
13  1 Y 1 A LYS 42  ? A LYS 42  
14  1 Y 1 A LYS 43  ? A LYS 43  
15  1 Y 1 A HIS 44  ? A HIS 44  
16  1 Y 1 A THR 45  ? A THR 45  
17  1 Y 1 A GLU 46  ? A GLU 46  
18  1 Y 1 A THR 47  ? A THR 47  
19  1 Y 1 A SER 48  ? A SER 48  
20  1 Y 1 A LEU 49  ? A LEU 49  
21  1 Y 1 A ILE 50  ? A ILE 50  
22  1 Y 1 A LYS 51  ? A LYS 51  
23  1 Y 1 A THR 52  ? A THR 52  
24  1 Y 1 A VAL 53  ? A VAL 53  
25  1 Y 1 A LYS 54  ? A LYS 54  
26  1 Y 1 A SER 55  ? A SER 55  
27  1 Y 1 A SER 56  ? A SER 56  
28  1 Y 1 A LEU 57  ? A LEU 57  
29  1 Y 1 A GLY 58  ? A GLY 58  
30  1 Y 1 A ARG 59  ? A ARG 59  
31  1 Y 1 A LEU 60  ? A LEU 60  
32  1 Y 1 A SER 61  ? A SER 61  
33  1 Y 1 A ILE 62  ? A ILE 62  
34  1 Y 1 A PHE 63  ? A PHE 63  
35  1 Y 1 A GLY 64  ? A GLY 64  
36  1 Y 1 A ASN 65  ? A ASN 65  
37  1 Y 1 A LYS 66  ? A LYS 66  
38  1 Y 1 A GLY 67  ? A GLY 67  
39  1 Y 1 A ARG 68  ? A ARG 68  
40  1 Y 1 A GLU 69  ? A GLU 69  
41  1 Y 1 A GLN 70  ? A GLN 70  
42  1 Y 1 A SER 71  ? A SER 71  
43  1 Y 1 A ARG 72  ? A ARG 72  
44  1 Y 1 A GLY 158 ? A GLY 158 
45  1 Y 1 A GLU 159 ? A GLU 159 
46  1 Y 1 A SER 160 ? A SER 160 
47  1 Y 1 A THR 161 ? A THR 161 
48  1 Y 1 A GLN 162 ? A GLN 162 
49  1 Y 1 A GLU 163 ? A GLU 163 
50  1 Y 1 A SER 164 ? A SER 164 
51  1 Y 1 A LYS 165 ? A LYS 165 
52  1 Y 1 A GLU 166 ? A GLU 166 
53  1 Y 1 A ASP 167 ? A ASP 167 
54  1 Y 1 A ASP 168 ? A ASP 168 
55  1 Y 1 A SER 169 ? A SER 169 
56  1 Y 1 A ILE 170 ? A ILE 170 
57  1 Y 1 A SER 171 ? A SER 171 
58  1 Y 1 A CYS 172 ? A CYS 172 
59  1 Y 1 A THR 173 ? A THR 173 
60  1 Y 1 A ILE 174 ? A ILE 174 
61  1 Y 1 A SER 175 ? A SER 175 
62  1 Y 1 A CYS 176 ? A CYS 176 
63  1 Y 1 A GLU 177 ? A GLU 177 
64  1 Y 1 A TYR 178 ? A TYR 178 
65  1 Y 1 A ASP 179 ? A ASP 179 
66  1 Y 1 A SER 180 ? A SER 180 
67  1 Y 1 A VAL 181 ? A VAL 181 
68  1 Y 1 A ARG 182 ? A ARG 182 
69  1 Y 1 A GLY 183 ? A GLY 183 
70  1 Y 1 A ARG 184 ? A ARG 184 
71  1 Y 1 A THR 185 ? A THR 185 
72  1 Y 1 A GLU 186 ? A GLU 186 
73  1 Y 1 A GLU 187 ? A GLU 187 
74  1 Y 1 A MET 188 ? A MET 188 
75  1 Y 1 A GLN 189 ? A GLN 189 
76  1 Y 1 A LEU 190 ? A LEU 190 
77  1 Y 1 A GLN 191 ? A GLN 191 
78  1 Y 1 A VAL 192 ? A VAL 192 
79  1 Y 1 A SER 193 ? A SER 193 
80  1 Y 1 A CYS 194 ? A CYS 194 
81  1 Y 1 A LEU 195 ? A LEU 195 
82  1 Y 1 A ASP 196 ? A ASP 196 
83  1 Y 1 A ASN 197 ? A ASN 197 
84  1 Y 1 A LEU 198 ? A LEU 198 
85  1 Y 1 A GLU 199 ? A GLU 199 
86  1 Y 1 A ASP 200 ? A ASP 200 
87  1 Y 1 A ASN 201 ? A ASN 201 
88  1 Y 1 A GLY 202 ? A GLY 202 
89  1 Y 1 A GLU 203 ? A GLU 203 
90  1 Y 1 A GLU 204 ? A GLU 204 
91  1 Y 1 A ALA 205 ? A ALA 205 
92  1 Y 1 A LEU 206 ? A LEU 206 
93  1 Y 1 A GLU 207 ? A GLU 207 
94  1 Y 1 A SER 208 ? A SER 208 
95  1 Y 1 A LEU 209 ? A LEU 209 
96  1 Y 1 A GLY 210 ? A GLY 210 
97  1 Y 1 A SER 211 ? A SER 211 
98  1 Y 1 A GLU 212 ? A GLU 212 
99  1 Y 1 A GLU 213 ? A GLU 213 
100 1 Y 1 A PRO 214 ? A PRO 214 
101 1 Y 1 A ILE 215 ? A ILE 215 
102 1 Y 1 A LYS 216 ? A LYS 216 
103 1 Y 1 A ALA 217 ? A ALA 217 
104 1 Y 1 A ASN 218 ? A ASN 218 
105 1 Y 1 A ASN 219 ? A ASN 219 
106 1 Y 1 A GLU 220 ? A GLU 220 
107 1 Y 1 A ASP 221 ? A ASP 221 
108 1 Y 1 A SER 222 ? A SER 222 
109 1 Y 1 A LYS 223 ? A LYS 223 
110 1 Y 1 A LEU 224 ? A LEU 224 
111 1 Y 1 A THR 225 ? A THR 225 
112 1 Y 1 A THR 226 ? A THR 226 
113 1 Y 1 A VAL 227 ? A VAL 227 
114 1 Y 1 A SER 228 ? A SER 228 
115 1 Y 1 A SER 229 ? A SER 229 
116 1 Y 1 A ARG 230 ? A ARG 230 
117 1 Y 1 A VAL 231 ? A VAL 231 
118 1 Y 1 A PHE 232 ? A PHE 232 
119 1 Y 1 A SER 233 ? A SER 233 
120 1 Y 1 A CYS 234 ? A CYS 234 
121 1 Y 1 A GLN 235 ? A GLN 235 
122 1 Y 1 A GLY 236 ? A GLY 236 
123 1 Y 1 A LYS 237 ? A LYS 237 
124 1 Y 1 A ASN 238 ? A ASN 238 
125 1 Y 1 A VAL 239 ? A VAL 239 
126 1 Y 1 A LYS 240 ? A LYS 240 
127 1 Y 1 A ILE 241 ? A ILE 241 
128 1 Y 1 A LYS 242 ? A LYS 242 
129 1 Y 1 A ILE 243 ? A ILE 243 
130 1 Y 1 A PRO 244 ? A PRO 244 
131 1 Y 1 A LEU 245 ? A LEU 245 
132 1 Y 1 A THR 246 ? A THR 246 
133 1 Y 1 A ASN 247 ? A ASN 247 
134 1 Y 1 A PRO 248 ? A PRO 248 
135 1 Y 1 A SER 249 ? A SER 249 
136 1 Y 1 A ARG 250 ? A ARG 250 
137 1 Y 1 A THR 251 ? A THR 251 
138 1 Y 1 A PHE 252 ? A PHE 252 
139 1 Y 1 A SER 253 ? A SER 253 
140 1 Y 1 A ALA 254 ? A ALA 254 
141 1 Y 1 A ILE 255 ? A ILE 255 
142 1 Y 1 A SER 256 ? A SER 256 
143 1 Y 1 A TYR 257 ? A TYR 257 
144 1 Y 1 A LEU 258 ? A LEU 258 
145 1 Y 1 A ILE 259 ? A ILE 259 
146 1 Y 1 A ASN 260 ? A ASN 260 
147 1 Y 1 A GLN 261 ? A GLN 261 
148 1 Y 1 A SER 262 ? A SER 262 
149 1 Y 1 A SER 263 ? A SER 263 
150 1 Y 1 A SER 264 ? A SER 264 
151 1 Y 1 A LYS 265 ? A LYS 265 
152 1 Y 1 A LYS 266 ? A LYS 266 
153 1 Y 1 A ASN 267 ? A ASN 267 
154 1 Y 1 A GLY 268 ? A GLY 268 
155 1 Y 1 A PRO 269 ? A PRO 269 
156 1 Y 1 A ASP 270 ? A ASP 270 
157 1 Y 1 A GLY 271 ? A GLY 271 
158 1 Y 1 A GLY 272 ? A GLY 272 
159 1 Y 1 A ASN 273 ? A ASN 273 
160 1 Y 1 A LYS 274 ? A LYS 274 
161 1 Y 1 A LEU 275 ? A LEU 275 
162 1 Y 1 A GLN 276 ? A GLN 276 
163 1 Y 1 A ILE 277 ? A ILE 277 
164 1 Y 1 A SER 278 ? A SER 278 
165 1 Y 1 A LYS 279 ? A LYS 279 
166 1 Y 1 B MET 1   ? B MET 1   
167 1 Y 1 B VAL 2   ? B VAL 2   
168 1 Y 1 B LYS 3   ? B LYS 3   
169 1 Y 1 B PHE 4   ? B PHE 4   
170 1 Y 1 B THR 5   ? B THR 5   
171 1 Y 1 B LYS 6   ? B LYS 6   
172 1 Y 1 B GLN 7   ? B GLN 7   
173 1 Y 1 B PHE 8   ? B PHE 8   
174 1 Y 1 B GLU 9   ? B GLU 9   
175 1 Y 1 B GLY 10  ? B GLY 10  
176 1 Y 1 B VAL 40  ? B VAL 40  
177 1 Y 1 B GLU 41  ? B GLU 41  
178 1 Y 1 B LYS 42  ? B LYS 42  
179 1 Y 1 B LYS 43  ? B LYS 43  
180 1 Y 1 B HIS 44  ? B HIS 44  
181 1 Y 1 B THR 45  ? B THR 45  
182 1 Y 1 B GLU 46  ? B GLU 46  
183 1 Y 1 B THR 47  ? B THR 47  
184 1 Y 1 B SER 48  ? B SER 48  
185 1 Y 1 B LEU 49  ? B LEU 49  
186 1 Y 1 B ILE 50  ? B ILE 50  
187 1 Y 1 B LYS 51  ? B LYS 51  
188 1 Y 1 B THR 52  ? B THR 52  
189 1 Y 1 B VAL 53  ? B VAL 53  
190 1 Y 1 B LYS 54  ? B LYS 54  
191 1 Y 1 B SER 55  ? B SER 55  
192 1 Y 1 B SER 56  ? B SER 56  
193 1 Y 1 B LEU 57  ? B LEU 57  
194 1 Y 1 B GLY 58  ? B GLY 58  
195 1 Y 1 B ARG 59  ? B ARG 59  
196 1 Y 1 B LEU 60  ? B LEU 60  
197 1 Y 1 B SER 61  ? B SER 61  
198 1 Y 1 B ILE 62  ? B ILE 62  
199 1 Y 1 B PHE 63  ? B PHE 63  
200 1 Y 1 B GLY 64  ? B GLY 64  
201 1 Y 1 B ASN 65  ? B ASN 65  
202 1 Y 1 B LYS 66  ? B LYS 66  
203 1 Y 1 B GLY 67  ? B GLY 67  
204 1 Y 1 B ARG 68  ? B ARG 68  
205 1 Y 1 B GLU 69  ? B GLU 69  
206 1 Y 1 B GLN 70  ? B GLN 70  
207 1 Y 1 B SER 71  ? B SER 71  
208 1 Y 1 B ARG 72  ? B ARG 72  
209 1 Y 1 B GLY 158 ? B GLY 158 
210 1 Y 1 B GLU 159 ? B GLU 159 
211 1 Y 1 B SER 160 ? B SER 160 
212 1 Y 1 B THR 161 ? B THR 161 
213 1 Y 1 B GLN 162 ? B GLN 162 
214 1 Y 1 B GLU 163 ? B GLU 163 
215 1 Y 1 B SER 164 ? B SER 164 
216 1 Y 1 B LYS 165 ? B LYS 165 
217 1 Y 1 B GLU 166 ? B GLU 166 
218 1 Y 1 B ASP 167 ? B ASP 167 
219 1 Y 1 B ASP 168 ? B ASP 168 
220 1 Y 1 B SER 169 ? B SER 169 
221 1 Y 1 B ILE 170 ? B ILE 170 
222 1 Y 1 B SER 171 ? B SER 171 
223 1 Y 1 B CYS 172 ? B CYS 172 
224 1 Y 1 B THR 173 ? B THR 173 
225 1 Y 1 B ILE 174 ? B ILE 174 
226 1 Y 1 B SER 175 ? B SER 175 
227 1 Y 1 B CYS 176 ? B CYS 176 
228 1 Y 1 B GLU 177 ? B GLU 177 
229 1 Y 1 B TYR 178 ? B TYR 178 
230 1 Y 1 B ASP 179 ? B ASP 179 
231 1 Y 1 B SER 180 ? B SER 180 
232 1 Y 1 B VAL 181 ? B VAL 181 
233 1 Y 1 B ARG 182 ? B ARG 182 
234 1 Y 1 B GLY 183 ? B GLY 183 
235 1 Y 1 B ARG 184 ? B ARG 184 
236 1 Y 1 B THR 185 ? B THR 185 
237 1 Y 1 B GLU 186 ? B GLU 186 
238 1 Y 1 B GLU 187 ? B GLU 187 
239 1 Y 1 B MET 188 ? B MET 188 
240 1 Y 1 B GLN 189 ? B GLN 189 
241 1 Y 1 B LEU 190 ? B LEU 190 
242 1 Y 1 B GLN 191 ? B GLN 191 
243 1 Y 1 B VAL 192 ? B VAL 192 
244 1 Y 1 B SER 193 ? B SER 193 
245 1 Y 1 B CYS 194 ? B CYS 194 
246 1 Y 1 B LEU 195 ? B LEU 195 
247 1 Y 1 B ASP 196 ? B ASP 196 
248 1 Y 1 B ASN 197 ? B ASN 197 
249 1 Y 1 B LEU 198 ? B LEU 198 
250 1 Y 1 B GLU 199 ? B GLU 199 
251 1 Y 1 B ASP 200 ? B ASP 200 
252 1 Y 1 B ASN 201 ? B ASN 201 
253 1 Y 1 B GLY 202 ? B GLY 202 
254 1 Y 1 B GLU 203 ? B GLU 203 
255 1 Y 1 B GLU 204 ? B GLU 204 
256 1 Y 1 B ALA 205 ? B ALA 205 
257 1 Y 1 B LEU 206 ? B LEU 206 
258 1 Y 1 B GLU 207 ? B GLU 207 
259 1 Y 1 B SER 208 ? B SER 208 
260 1 Y 1 B LEU 209 ? B LEU 209 
261 1 Y 1 B GLY 210 ? B GLY 210 
262 1 Y 1 B SER 211 ? B SER 211 
263 1 Y 1 B GLU 212 ? B GLU 212 
264 1 Y 1 B GLU 213 ? B GLU 213 
265 1 Y 1 B PRO 214 ? B PRO 214 
266 1 Y 1 B ILE 215 ? B ILE 215 
267 1 Y 1 B LYS 216 ? B LYS 216 
268 1 Y 1 B ALA 217 ? B ALA 217 
269 1 Y 1 B ASN 218 ? B ASN 218 
270 1 Y 1 B ASN 219 ? B ASN 219 
271 1 Y 1 B GLU 220 ? B GLU 220 
272 1 Y 1 B ASP 221 ? B ASP 221 
273 1 Y 1 B SER 222 ? B SER 222 
274 1 Y 1 B LYS 223 ? B LYS 223 
275 1 Y 1 B LEU 224 ? B LEU 224 
276 1 Y 1 B THR 225 ? B THR 225 
277 1 Y 1 B THR 226 ? B THR 226 
278 1 Y 1 B VAL 227 ? B VAL 227 
279 1 Y 1 B SER 228 ? B SER 228 
280 1 Y 1 B SER 229 ? B SER 229 
281 1 Y 1 B ARG 230 ? B ARG 230 
282 1 Y 1 B VAL 231 ? B VAL 231 
283 1 Y 1 B PHE 232 ? B PHE 232 
284 1 Y 1 B SER 233 ? B SER 233 
285 1 Y 1 B CYS 234 ? B CYS 234 
286 1 Y 1 B GLN 235 ? B GLN 235 
287 1 Y 1 B GLY 236 ? B GLY 236 
288 1 Y 1 B LYS 237 ? B LYS 237 
289 1 Y 1 B ASN 238 ? B ASN 238 
290 1 Y 1 B VAL 239 ? B VAL 239 
291 1 Y 1 B LYS 240 ? B LYS 240 
292 1 Y 1 B ILE 241 ? B ILE 241 
293 1 Y 1 B LYS 242 ? B LYS 242 
294 1 Y 1 B ILE 243 ? B ILE 243 
295 1 Y 1 B PRO 244 ? B PRO 244 
296 1 Y 1 B LEU 245 ? B LEU 245 
297 1 Y 1 B THR 246 ? B THR 246 
298 1 Y 1 B ASN 247 ? B ASN 247 
299 1 Y 1 B PRO 248 ? B PRO 248 
300 1 Y 1 B SER 249 ? B SER 249 
301 1 Y 1 B ARG 250 ? B ARG 250 
302 1 Y 1 B THR 251 ? B THR 251 
303 1 Y 1 B PHE 252 ? B PHE 252 
304 1 Y 1 B SER 253 ? B SER 253 
305 1 Y 1 B ALA 254 ? B ALA 254 
306 1 Y 1 B ILE 255 ? B ILE 255 
307 1 Y 1 B SER 256 ? B SER 256 
308 1 Y 1 B TYR 257 ? B TYR 257 
309 1 Y 1 B LEU 258 ? B LEU 258 
310 1 Y 1 B ILE 259 ? B ILE 259 
311 1 Y 1 B ASN 260 ? B ASN 260 
312 1 Y 1 B GLN 261 ? B GLN 261 
313 1 Y 1 B SER 262 ? B SER 262 
314 1 Y 1 B SER 263 ? B SER 263 
315 1 Y 1 B SER 264 ? B SER 264 
316 1 Y 1 B LYS 265 ? B LYS 265 
317 1 Y 1 B LYS 266 ? B LYS 266 
318 1 Y 1 B ASN 267 ? B ASN 267 
319 1 Y 1 B GLY 268 ? B GLY 268 
320 1 Y 1 B PRO 269 ? B PRO 269 
321 1 Y 1 B ASP 270 ? B ASP 270 
322 1 Y 1 B GLY 271 ? B GLY 271 
323 1 Y 1 B GLY 272 ? B GLY 272 
324 1 Y 1 B ASN 273 ? B ASN 273 
325 1 Y 1 B LYS 274 ? B LYS 274 
326 1 Y 1 B LEU 275 ? B LEU 275 
327 1 Y 1 B GLN 276 ? B GLN 276 
328 1 Y 1 B ILE 277 ? B ILE 277 
329 1 Y 1 B SER 278 ? B SER 278 
330 1 Y 1 B LYS 279 ? B LYS 279 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
IHP C1   C N N 158 
IHP C2   C N N 159 
IHP C3   C N N 160 
IHP C4   C N N 161 
IHP C5   C N N 162 
IHP C6   C N N 163 
IHP O11  O N N 164 
IHP P1   P N N 165 
IHP O21  O N N 166 
IHP O31  O N N 167 
IHP O41  O N N 168 
IHP O12  O N N 169 
IHP P2   P N N 170 
IHP O22  O N N 171 
IHP O32  O N N 172 
IHP O42  O N N 173 
IHP O13  O N N 174 
IHP P3   P N N 175 
IHP O23  O N N 176 
IHP O33  O N N 177 
IHP O43  O N N 178 
IHP O14  O N N 179 
IHP P4   P N N 180 
IHP O24  O N N 181 
IHP O34  O N N 182 
IHP O44  O N N 183 
IHP O15  O N N 184 
IHP P5   P N N 185 
IHP O25  O N N 186 
IHP O35  O N N 187 
IHP O45  O N N 188 
IHP O16  O N N 189 
IHP P6   P N N 190 
IHP O26  O N N 191 
IHP O36  O N N 192 
IHP O46  O N N 193 
IHP H1   H N N 194 
IHP H2   H N N 195 
IHP H3   H N N 196 
IHP H4   H N N 197 
IHP H5   H N N 198 
IHP H6   H N N 199 
IHP H31  H N N 200 
IHP H41  H N N 201 
IHP H32  H N N 202 
IHP H42  H N N 203 
IHP H33  H N N 204 
IHP H43  H N N 205 
IHP H34  H N N 206 
IHP H44  H N N 207 
IHP H35  H N N 208 
IHP H45  H N N 209 
IHP H36  H N N 210 
IHP H46  H N N 211 
ILE N    N N N 212 
ILE CA   C N S 213 
ILE C    C N N 214 
ILE O    O N N 215 
ILE CB   C N S 216 
ILE CG1  C N N 217 
ILE CG2  C N N 218 
ILE CD1  C N N 219 
ILE OXT  O N N 220 
ILE H    H N N 221 
ILE H2   H N N 222 
ILE HA   H N N 223 
ILE HB   H N N 224 
ILE HG12 H N N 225 
ILE HG13 H N N 226 
ILE HG21 H N N 227 
ILE HG22 H N N 228 
ILE HG23 H N N 229 
ILE HD11 H N N 230 
ILE HD12 H N N 231 
ILE HD13 H N N 232 
ILE HXT  H N N 233 
LEU N    N N N 234 
LEU CA   C N S 235 
LEU C    C N N 236 
LEU O    O N N 237 
LEU CB   C N N 238 
LEU CG   C N N 239 
LEU CD1  C N N 240 
LEU CD2  C N N 241 
LEU OXT  O N N 242 
LEU H    H N N 243 
LEU H2   H N N 244 
LEU HA   H N N 245 
LEU HB2  H N N 246 
LEU HB3  H N N 247 
LEU HG   H N N 248 
LEU HD11 H N N 249 
LEU HD12 H N N 250 
LEU HD13 H N N 251 
LEU HD21 H N N 252 
LEU HD22 H N N 253 
LEU HD23 H N N 254 
LEU HXT  H N N 255 
LYS N    N N N 256 
LYS CA   C N S 257 
LYS C    C N N 258 
LYS O    O N N 259 
LYS CB   C N N 260 
LYS CG   C N N 261 
LYS CD   C N N 262 
LYS CE   C N N 263 
LYS NZ   N N N 264 
LYS OXT  O N N 265 
LYS H    H N N 266 
LYS H2   H N N 267 
LYS HA   H N N 268 
LYS HB2  H N N 269 
LYS HB3  H N N 270 
LYS HG2  H N N 271 
LYS HG3  H N N 272 
LYS HD2  H N N 273 
LYS HD3  H N N 274 
LYS HE2  H N N 275 
LYS HE3  H N N 276 
LYS HZ1  H N N 277 
LYS HZ2  H N N 278 
LYS HZ3  H N N 279 
LYS HXT  H N N 280 
MET N    N N N 281 
MET CA   C N S 282 
MET C    C N N 283 
MET O    O N N 284 
MET CB   C N N 285 
MET CG   C N N 286 
MET SD   S N N 287 
MET CE   C N N 288 
MET OXT  O N N 289 
MET H    H N N 290 
MET H2   H N N 291 
MET HA   H N N 292 
MET HB2  H N N 293 
MET HB3  H N N 294 
MET HG2  H N N 295 
MET HG3  H N N 296 
MET HE1  H N N 297 
MET HE2  H N N 298 
MET HE3  H N N 299 
MET HXT  H N N 300 
PHE N    N N N 301 
PHE CA   C N S 302 
PHE C    C N N 303 
PHE O    O N N 304 
PHE CB   C N N 305 
PHE CG   C Y N 306 
PHE CD1  C Y N 307 
PHE CD2  C Y N 308 
PHE CE1  C Y N 309 
PHE CE2  C Y N 310 
PHE CZ   C Y N 311 
PHE OXT  O N N 312 
PHE H    H N N 313 
PHE H2   H N N 314 
PHE HA   H N N 315 
PHE HB2  H N N 316 
PHE HB3  H N N 317 
PHE HD1  H N N 318 
PHE HD2  H N N 319 
PHE HE1  H N N 320 
PHE HE2  H N N 321 
PHE HZ   H N N 322 
PHE HXT  H N N 323 
PO4 P    P N N 324 
PO4 O1   O N N 325 
PO4 O2   O N N 326 
PO4 O3   O N N 327 
PO4 O4   O N N 328 
PRO N    N N N 329 
PRO CA   C N S 330 
PRO C    C N N 331 
PRO O    O N N 332 
PRO CB   C N N 333 
PRO CG   C N N 334 
PRO CD   C N N 335 
PRO OXT  O N N 336 
PRO H    H N N 337 
PRO HA   H N N 338 
PRO HB2  H N N 339 
PRO HB3  H N N 340 
PRO HG2  H N N 341 
PRO HG3  H N N 342 
PRO HD2  H N N 343 
PRO HD3  H N N 344 
PRO HXT  H N N 345 
SER N    N N N 346 
SER CA   C N S 347 
SER C    C N N 348 
SER O    O N N 349 
SER CB   C N N 350 
SER OG   O N N 351 
SER OXT  O N N 352 
SER H    H N N 353 
SER H2   H N N 354 
SER HA   H N N 355 
SER HB2  H N N 356 
SER HB3  H N N 357 
SER HG   H N N 358 
SER HXT  H N N 359 
THR N    N N N 360 
THR CA   C N S 361 
THR C    C N N 362 
THR O    O N N 363 
THR CB   C N R 364 
THR OG1  O N N 365 
THR CG2  C N N 366 
THR OXT  O N N 367 
THR H    H N N 368 
THR H2   H N N 369 
THR HA   H N N 370 
THR HB   H N N 371 
THR HG1  H N N 372 
THR HG21 H N N 373 
THR HG22 H N N 374 
THR HG23 H N N 375 
THR HXT  H N N 376 
TRP N    N N N 377 
TRP CA   C N S 378 
TRP C    C N N 379 
TRP O    O N N 380 
TRP CB   C N N 381 
TRP CG   C Y N 382 
TRP CD1  C Y N 383 
TRP CD2  C Y N 384 
TRP NE1  N Y N 385 
TRP CE2  C Y N 386 
TRP CE3  C Y N 387 
TRP CZ2  C Y N 388 
TRP CZ3  C Y N 389 
TRP CH2  C Y N 390 
TRP OXT  O N N 391 
TRP H    H N N 392 
TRP H2   H N N 393 
TRP HA   H N N 394 
TRP HB2  H N N 395 
TRP HB3  H N N 396 
TRP HD1  H N N 397 
TRP HE1  H N N 398 
TRP HE3  H N N 399 
TRP HZ2  H N N 400 
TRP HZ3  H N N 401 
TRP HH2  H N N 402 
TRP HXT  H N N 403 
TYR N    N N N 404 
TYR CA   C N S 405 
TYR C    C N N 406 
TYR O    O N N 407 
TYR CB   C N N 408 
TYR CG   C Y N 409 
TYR CD1  C Y N 410 
TYR CD2  C Y N 411 
TYR CE1  C Y N 412 
TYR CE2  C Y N 413 
TYR CZ   C Y N 414 
TYR OH   O N N 415 
TYR OXT  O N N 416 
TYR H    H N N 417 
TYR H2   H N N 418 
TYR HA   H N N 419 
TYR HB2  H N N 420 
TYR HB3  H N N 421 
TYR HD1  H N N 422 
TYR HD2  H N N 423 
TYR HE1  H N N 424 
TYR HE2  H N N 425 
TYR HH   H N N 426 
TYR HXT  H N N 427 
VAL N    N N N 428 
VAL CA   C N S 429 
VAL C    C N N 430 
VAL O    O N N 431 
VAL CB   C N N 432 
VAL CG1  C N N 433 
VAL CG2  C N N 434 
VAL OXT  O N N 435 
VAL H    H N N 436 
VAL H2   H N N 437 
VAL HA   H N N 438 
VAL HB   H N N 439 
VAL HG11 H N N 440 
VAL HG12 H N N 441 
VAL HG13 H N N 442 
VAL HG21 H N N 443 
VAL HG22 H N N 444 
VAL HG23 H N N 445 
VAL HXT  H N N 446 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
IHP C1  C2   sing N N 150 
IHP C1  C6   sing N N 151 
IHP C1  O11  sing N N 152 
IHP C1  H1   sing N N 153 
IHP C2  C3   sing N N 154 
IHP C2  O12  sing N N 155 
IHP C2  H2   sing N N 156 
IHP C3  C4   sing N N 157 
IHP C3  O13  sing N N 158 
IHP C3  H3   sing N N 159 
IHP C4  C5   sing N N 160 
IHP C4  O14  sing N N 161 
IHP C4  H4   sing N N 162 
IHP C5  C6   sing N N 163 
IHP C5  O15  sing N N 164 
IHP C5  H5   sing N N 165 
IHP C6  O16  sing N N 166 
IHP C6  H6   sing N N 167 
IHP O11 P1   sing N N 168 
IHP P1  O21  doub N N 169 
IHP P1  O31  sing N N 170 
IHP P1  O41  sing N N 171 
IHP O31 H31  sing N N 172 
IHP O41 H41  sing N N 173 
IHP O12 P2   sing N N 174 
IHP P2  O22  doub N N 175 
IHP P2  O32  sing N N 176 
IHP P2  O42  sing N N 177 
IHP O32 H32  sing N N 178 
IHP O42 H42  sing N N 179 
IHP O13 P3   sing N N 180 
IHP P3  O23  doub N N 181 
IHP P3  O33  sing N N 182 
IHP P3  O43  sing N N 183 
IHP O33 H33  sing N N 184 
IHP O43 H43  sing N N 185 
IHP O14 P4   sing N N 186 
IHP P4  O24  doub N N 187 
IHP P4  O34  sing N N 188 
IHP P4  O44  sing N N 189 
IHP O34 H34  sing N N 190 
IHP O44 H44  sing N N 191 
IHP O15 P5   sing N N 192 
IHP P5  O25  doub N N 193 
IHP P5  O35  sing N N 194 
IHP P5  O45  sing N N 195 
IHP O35 H35  sing N N 196 
IHP O45 H45  sing N N 197 
IHP O16 P6   sing N N 198 
IHP P6  O26  doub N N 199 
IHP P6  O36  sing N N 200 
IHP P6  O46  sing N N 201 
IHP O36 H36  sing N N 202 
IHP O46 H46  sing N N 203 
ILE N   CA   sing N N 204 
ILE N   H    sing N N 205 
ILE N   H2   sing N N 206 
ILE CA  C    sing N N 207 
ILE CA  CB   sing N N 208 
ILE CA  HA   sing N N 209 
ILE C   O    doub N N 210 
ILE C   OXT  sing N N 211 
ILE CB  CG1  sing N N 212 
ILE CB  CG2  sing N N 213 
ILE CB  HB   sing N N 214 
ILE CG1 CD1  sing N N 215 
ILE CG1 HG12 sing N N 216 
ILE CG1 HG13 sing N N 217 
ILE CG2 HG21 sing N N 218 
ILE CG2 HG22 sing N N 219 
ILE CG2 HG23 sing N N 220 
ILE CD1 HD11 sing N N 221 
ILE CD1 HD12 sing N N 222 
ILE CD1 HD13 sing N N 223 
ILE OXT HXT  sing N N 224 
LEU N   CA   sing N N 225 
LEU N   H    sing N N 226 
LEU N   H2   sing N N 227 
LEU CA  C    sing N N 228 
LEU CA  CB   sing N N 229 
LEU CA  HA   sing N N 230 
LEU C   O    doub N N 231 
LEU C   OXT  sing N N 232 
LEU CB  CG   sing N N 233 
LEU CB  HB2  sing N N 234 
LEU CB  HB3  sing N N 235 
LEU CG  CD1  sing N N 236 
LEU CG  CD2  sing N N 237 
LEU CG  HG   sing N N 238 
LEU CD1 HD11 sing N N 239 
LEU CD1 HD12 sing N N 240 
LEU CD1 HD13 sing N N 241 
LEU CD2 HD21 sing N N 242 
LEU CD2 HD22 sing N N 243 
LEU CD2 HD23 sing N N 244 
LEU OXT HXT  sing N N 245 
LYS N   CA   sing N N 246 
LYS N   H    sing N N 247 
LYS N   H2   sing N N 248 
LYS CA  C    sing N N 249 
LYS CA  CB   sing N N 250 
LYS CA  HA   sing N N 251 
LYS C   O    doub N N 252 
LYS C   OXT  sing N N 253 
LYS CB  CG   sing N N 254 
LYS CB  HB2  sing N N 255 
LYS CB  HB3  sing N N 256 
LYS CG  CD   sing N N 257 
LYS CG  HG2  sing N N 258 
LYS CG  HG3  sing N N 259 
LYS CD  CE   sing N N 260 
LYS CD  HD2  sing N N 261 
LYS CD  HD3  sing N N 262 
LYS CE  NZ   sing N N 263 
LYS CE  HE2  sing N N 264 
LYS CE  HE3  sing N N 265 
LYS NZ  HZ1  sing N N 266 
LYS NZ  HZ2  sing N N 267 
LYS NZ  HZ3  sing N N 268 
LYS OXT HXT  sing N N 269 
MET N   CA   sing N N 270 
MET N   H    sing N N 271 
MET N   H2   sing N N 272 
MET CA  C    sing N N 273 
MET CA  CB   sing N N 274 
MET CA  HA   sing N N 275 
MET C   O    doub N N 276 
MET C   OXT  sing N N 277 
MET CB  CG   sing N N 278 
MET CB  HB2  sing N N 279 
MET CB  HB3  sing N N 280 
MET CG  SD   sing N N 281 
MET CG  HG2  sing N N 282 
MET CG  HG3  sing N N 283 
MET SD  CE   sing N N 284 
MET CE  HE1  sing N N 285 
MET CE  HE2  sing N N 286 
MET CE  HE3  sing N N 287 
MET OXT HXT  sing N N 288 
PHE N   CA   sing N N 289 
PHE N   H    sing N N 290 
PHE N   H2   sing N N 291 
PHE CA  C    sing N N 292 
PHE CA  CB   sing N N 293 
PHE CA  HA   sing N N 294 
PHE C   O    doub N N 295 
PHE C   OXT  sing N N 296 
PHE CB  CG   sing N N 297 
PHE CB  HB2  sing N N 298 
PHE CB  HB3  sing N N 299 
PHE CG  CD1  doub Y N 300 
PHE CG  CD2  sing Y N 301 
PHE CD1 CE1  sing Y N 302 
PHE CD1 HD1  sing N N 303 
PHE CD2 CE2  doub Y N 304 
PHE CD2 HD2  sing N N 305 
PHE CE1 CZ   doub Y N 306 
PHE CE1 HE1  sing N N 307 
PHE CE2 CZ   sing Y N 308 
PHE CE2 HE2  sing N N 309 
PHE CZ  HZ   sing N N 310 
PHE OXT HXT  sing N N 311 
PO4 P   O1   doub N N 312 
PO4 P   O2   sing N N 313 
PO4 P   O3   sing N N 314 
PO4 P   O4   sing N N 315 
PRO N   CA   sing N N 316 
PRO N   CD   sing N N 317 
PRO N   H    sing N N 318 
PRO CA  C    sing N N 319 
PRO CA  CB   sing N N 320 
PRO CA  HA   sing N N 321 
PRO C   O    doub N N 322 
PRO C   OXT  sing N N 323 
PRO CB  CG   sing N N 324 
PRO CB  HB2  sing N N 325 
PRO CB  HB3  sing N N 326 
PRO CG  CD   sing N N 327 
PRO CG  HG2  sing N N 328 
PRO CG  HG3  sing N N 329 
PRO CD  HD2  sing N N 330 
PRO CD  HD3  sing N N 331 
PRO OXT HXT  sing N N 332 
SER N   CA   sing N N 333 
SER N   H    sing N N 334 
SER N   H2   sing N N 335 
SER CA  C    sing N N 336 
SER CA  CB   sing N N 337 
SER CA  HA   sing N N 338 
SER C   O    doub N N 339 
SER C   OXT  sing N N 340 
SER CB  OG   sing N N 341 
SER CB  HB2  sing N N 342 
SER CB  HB3  sing N N 343 
SER OG  HG   sing N N 344 
SER OXT HXT  sing N N 345 
THR N   CA   sing N N 346 
THR N   H    sing N N 347 
THR N   H2   sing N N 348 
THR CA  C    sing N N 349 
THR CA  CB   sing N N 350 
THR CA  HA   sing N N 351 
THR C   O    doub N N 352 
THR C   OXT  sing N N 353 
THR CB  OG1  sing N N 354 
THR CB  CG2  sing N N 355 
THR CB  HB   sing N N 356 
THR OG1 HG1  sing N N 357 
THR CG2 HG21 sing N N 358 
THR CG2 HG22 sing N N 359 
THR CG2 HG23 sing N N 360 
THR OXT HXT  sing N N 361 
TRP N   CA   sing N N 362 
TRP N   H    sing N N 363 
TRP N   H2   sing N N 364 
TRP CA  C    sing N N 365 
TRP CA  CB   sing N N 366 
TRP CA  HA   sing N N 367 
TRP C   O    doub N N 368 
TRP C   OXT  sing N N 369 
TRP CB  CG   sing N N 370 
TRP CB  HB2  sing N N 371 
TRP CB  HB3  sing N N 372 
TRP CG  CD1  doub Y N 373 
TRP CG  CD2  sing Y N 374 
TRP CD1 NE1  sing Y N 375 
TRP CD1 HD1  sing N N 376 
TRP CD2 CE2  doub Y N 377 
TRP CD2 CE3  sing Y N 378 
TRP NE1 CE2  sing Y N 379 
TRP NE1 HE1  sing N N 380 
TRP CE2 CZ2  sing Y N 381 
TRP CE3 CZ3  doub Y N 382 
TRP CE3 HE3  sing N N 383 
TRP CZ2 CH2  doub Y N 384 
TRP CZ2 HZ2  sing N N 385 
TRP CZ3 CH2  sing Y N 386 
TRP CZ3 HZ3  sing N N 387 
TRP CH2 HH2  sing N N 388 
TRP OXT HXT  sing N N 389 
TYR N   CA   sing N N 390 
TYR N   H    sing N N 391 
TYR N   H2   sing N N 392 
TYR CA  C    sing N N 393 
TYR CA  CB   sing N N 394 
TYR CA  HA   sing N N 395 
TYR C   O    doub N N 396 
TYR C   OXT  sing N N 397 
TYR CB  CG   sing N N 398 
TYR CB  HB2  sing N N 399 
TYR CB  HB3  sing N N 400 
TYR CG  CD1  doub Y N 401 
TYR CG  CD2  sing Y N 402 
TYR CD1 CE1  sing Y N 403 
TYR CD1 HD1  sing N N 404 
TYR CD2 CE2  doub Y N 405 
TYR CD2 HD2  sing N N 406 
TYR CE1 CZ   doub Y N 407 
TYR CE1 HE1  sing N N 408 
TYR CE2 CZ   sing Y N 409 
TYR CE2 HE2  sing N N 410 
TYR CZ  OH   sing N N 411 
TYR OH  HH   sing N N 412 
TYR OXT HXT  sing N N 413 
VAL N   CA   sing N N 414 
VAL N   H    sing N N 415 
VAL N   H2   sing N N 416 
VAL CA  C    sing N N 417 
VAL CA  CB   sing N N 418 
VAL CA  HA   sing N N 419 
VAL C   O    doub N N 420 
VAL C   OXT  sing N N 421 
VAL CB  CG1  sing N N 422 
VAL CB  CG2  sing N N 423 
VAL CB  HB   sing N N 424 
VAL CG1 HG11 sing N N 425 
VAL CG1 HG12 sing N N 426 
VAL CG1 HG13 sing N N 427 
VAL CG2 HG21 sing N N 428 
VAL CG2 HG22 sing N N 429 
VAL CG2 HG23 sing N N 430 
VAL OXT HXT  sing N N 431 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-26 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9IK4 
_em_admin.last_update        2025-03-05 
_em_admin.map_release_date   2025-01-22 
_em_admin.title              'Cryo-EM structure of Arabidopsis thaliana phosphate transporter PHO1;H1' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          3702 
_em_entity_assembly_naturalsource.organism             'Arabidopsis thaliana' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         58.5 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOCONTINUUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?          
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.14_3260: 
'IMAGE ACQUISITION'        ? 3  1 ? 1 ?      ?          
MASKING                    ? 4  1 1 1 ?      ?          
'CTF CORRECTION'           ? 5  1 ? ? ?      ?          
'LAYERLINE INDEXING'       ? 6  1 1 1 ?      ?          
'DIFFRACTION INDEXING'     ? 7  1 1 1 ?      ?          
'MODEL FITTING'            ? 8  1 1 1 ?      ?          
OTHER                      ? 9  1 1 1 ?      ?          
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?          
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?          
CLASSIFICATION             ? 12 1 ? ? ?      ?          
RECONSTRUCTION             ? 13 1 ? ? ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9IK4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . GLN A 1 11  ? 132.318 116.897 80.615  1.00 62.87  ? 11   GLN A N   1 
ATOM   2     C CA  . GLN A 1 11  ? 131.456 117.996 80.204  1.00 62.87  ? 11   GLN A CA  1 
ATOM   3     C C   . GLN A 1 11  ? 132.244 119.295 80.106  1.00 62.87  ? 11   GLN A C   1 
ATOM   4     O O   . GLN A 1 11  ? 132.580 119.909 81.119  1.00 62.87  ? 11   GLN A O   1 
ATOM   5     C CB  . GLN A 1 11  ? 130.288 118.158 81.180  1.00 62.87  ? 11   GLN A CB  1 
ATOM   6     C CG  . GLN A 1 11  ? 129.252 117.040 81.136  1.00 62.87  ? 11   GLN A CG  1 
ATOM   7     C CD  . GLN A 1 11  ? 128.458 117.003 79.840  1.00 62.87  ? 11   GLN A CD  1 
ATOM   8     O OE1 . GLN A 1 11  ? 128.901 116.446 78.835  1.00 62.87  ? 11   GLN A OE1 1 
ATOM   9     N NE2 . GLN A 1 11  ? 127.271 117.594 79.864  1.00 62.87  ? 11   GLN A NE2 1 
ATOM   10    N N   . LEU A 1 12  ? 132.547 119.705 78.872  1.00 56.94  ? 12   LEU A N   1 
ATOM   11    C CA  . LEU A 1 12  ? 133.213 120.986 78.666  1.00 56.94  ? 12   LEU A CA  1 
ATOM   12    C C   . LEU A 1 12  ? 132.242 122.143 78.870  1.00 56.94  ? 12   LEU A C   1 
ATOM   13    O O   . LEU A 1 12  ? 132.614 123.185 79.421  1.00 56.94  ? 12   LEU A O   1 
ATOM   14    C CB  . LEU A 1 12  ? 133.860 121.035 77.274  1.00 56.94  ? 12   LEU A CB  1 
ATOM   15    C CG  . LEU A 1 12  ? 133.079 121.159 75.957  1.00 56.94  ? 12   LEU A CG  1 
ATOM   16    C CD1 . LEU A 1 12  ? 134.003 121.647 74.856  1.00 56.94  ? 12   LEU A CD1 1 
ATOM   17    C CD2 . LEU A 1 12  ? 132.420 119.848 75.538  1.00 56.94  ? 12   LEU A CD2 1 
ATOM   18    N N   . VAL A 1 13  ? 130.997 121.973 78.440  1.00 59.25  ? 13   VAL A N   1 
ATOM   19    C CA  . VAL A 1 13  ? 129.930 122.936 78.691  1.00 59.25  ? 13   VAL A CA  1 
ATOM   20    C C   . VAL A 1 13  ? 128.828 122.192 79.436  1.00 59.25  ? 13   VAL A C   1 
ATOM   21    O O   . VAL A 1 13  ? 128.708 120.967 79.286  1.00 59.25  ? 13   VAL A O   1 
ATOM   22    C CB  . VAL A 1 13  ? 129.419 123.565 77.383  1.00 59.25  ? 13   VAL A CB  1 
ATOM   23    C CG1 . VAL A 1 13  ? 130.429 124.568 76.852  1.00 59.25  ? 13   VAL A CG1 1 
ATOM   24    C CG2 . VAL A 1 13  ? 129.130 122.489 76.343  1.00 59.25  ? 13   VAL A CG2 1 
ATOM   25    N N   . PRO A 1 14  ? 128.033 122.866 80.274  1.00 61.30  ? 14   PRO A N   1 
ATOM   26    C CA  . PRO A 1 14  ? 126.906 122.182 80.920  1.00 61.30  ? 14   PRO A CA  1 
ATOM   27    C C   . PRO A 1 14  ? 125.826 121.798 79.922  1.00 61.30  ? 14   PRO A C   1 
ATOM   28    O O   . PRO A 1 14  ? 125.140 122.665 79.372  1.00 61.30  ? 14   PRO A O   1 
ATOM   29    C CB  . PRO A 1 14  ? 126.400 123.219 81.933  1.00 61.30  ? 14   PRO A CB  1 
ATOM   30    C CG  . PRO A 1 14  ? 127.564 124.131 82.158  1.00 61.30  ? 14   PRO A CG  1 
ATOM   31    C CD  . PRO A 1 14  ? 128.255 124.209 80.837  1.00 61.30  ? 14   PRO A CD  1 
ATOM   32    N N   . GLU A 1 15  ? 125.675 120.499 79.676  1.00 58.77  ? 15   GLU A N   1 
ATOM   33    C CA  . GLU A 1 15  ? 124.744 119.988 78.674  1.00 58.77  ? 15   GLU A CA  1 
ATOM   34    C C   . GLU A 1 15  ? 123.791 119.000 79.342  1.00 58.77  ? 15   GLU A C   1 
ATOM   35    O O   . GLU A 1 15  ? 124.019 117.789 79.352  1.00 58.77  ? 15   GLU A O   1 
ATOM   36    C CB  . GLU A 1 15  ? 125.503 119.349 77.494  1.00 58.77  ? 15   GLU A CB  1 
ATOM   37    C CG  . GLU A 1 15  ? 124.624 118.843 76.350  1.00 58.77  ? 15   GLU A CG  1 
ATOM   38    C CD  . GLU A 1 15  ? 123.512 119.803 75.984  1.00 58.77  ? 15   GLU A CD  1 
ATOM   39    O OE1 . GLU A 1 15  ? 123.809 120.970 75.654  1.00 58.77  ? 15   GLU A OE1 1 
ATOM   40    O OE2 . GLU A 1 15  ? 122.335 119.387 76.026  1.00 58.77  ? 15   GLU A OE2 1 
ATOM   41    N N   . TRP A 1 16  ? 122.738 119.541 79.948  1.00 57.50  ? 16   TRP A N   1 
ATOM   42    C CA  . TRP A 1 16  ? 121.486 118.817 80.167  1.00 57.50  ? 16   TRP A CA  1 
ATOM   43    C C   . TRP A 1 16  ? 120.405 119.889 79.989  1.00 57.50  ? 16   TRP A C   1 
ATOM   44    O O   . TRP A 1 16  ? 120.065 120.639 80.906  1.00 57.50  ? 16   TRP A O   1 
ATOM   45    C CB  . TRP A 1 16  ? 121.433 118.081 81.517  1.00 57.50  ? 16   TRP A CB  1 
ATOM   46    C CG  . TRP A 1 16  ? 121.479 118.895 82.808  1.00 57.50  ? 16   TRP A CG  1 
ATOM   47    C CD1 . TRP A 1 16  ? 120.437 119.111 83.663  1.00 57.50  ? 16   TRP A CD1 1 
ATOM   48    C CD2 . TRP A 1 16  ? 122.604 119.588 83.370  1.00 57.50  ? 16   TRP A CD2 1 
ATOM   49    N NE1 . TRP A 1 16  ? 120.837 119.891 84.717  1.00 57.50  ? 16   TRP A NE1 1 
ATOM   50    C CE2 . TRP A 1 16  ? 122.164 120.197 84.563  1.00 57.50  ? 16   TRP A CE2 1 
ATOM   51    C CE3 . TRP A 1 16  ? 123.938 119.752 82.983  1.00 57.50  ? 16   TRP A CE3 1 
ATOM   52    C CZ2 . TRP A 1 16  ? 123.009 120.955 85.370  1.00 57.50  ? 16   TRP A CZ2 1 
ATOM   53    C CZ3 . TRP A 1 16  ? 124.774 120.506 83.787  1.00 57.50  ? 16   TRP A CZ3 1 
ATOM   54    C CH2 . TRP A 1 16  ? 124.307 121.096 84.966  1.00 57.50  ? 16   TRP A CH2 1 
ATOM   55    N N   . LYS A 1 17  ? 119.895 120.007 78.767  1.00 61.36  ? 17   LYS A N   1 
ATOM   56    C CA  . LYS A 1 17  ? 119.034 121.154 78.517  1.00 61.36  ? 17   LYS A CA  1 
ATOM   57    C C   . LYS A 1 17  ? 117.563 120.766 78.470  1.00 61.36  ? 17   LYS A C   1 
ATOM   58    O O   . LYS A 1 17  ? 116.747 121.344 79.194  1.00 61.36  ? 17   LYS A O   1 
ATOM   59    C CB  . LYS A 1 17  ? 119.472 121.867 77.234  1.00 61.36  ? 17   LYS A CB  1 
ATOM   60    C CG  . LYS A 1 17  ? 120.809 122.618 77.367  1.00 61.36  ? 17   LYS A CG  1 
ATOM   61    C CD  . LYS A 1 17  ? 121.016 123.269 78.748  1.00 61.36  ? 17   LYS A CD  1 
ATOM   62    C CE  . LYS A 1 17  ? 120.246 124.581 78.912  1.00 61.36  ? 17   LYS A CE  1 
ATOM   63    N NZ  . LYS A 1 17  ? 120.197 125.006 80.338  1.00 61.36  ? 17   LYS A NZ  1 
ATOM   64    N N   . ASP A 1 18  ? 117.207 119.794 77.638  1.00 65.24  ? 18   ASP A N   1 
ATOM   65    C CA  . ASP A 1 18  ? 115.900 119.181 77.799  1.00 65.24  ? 18   ASP A CA  1 
ATOM   66    C C   . ASP A 1 18  ? 115.851 118.288 79.028  1.00 65.24  ? 18   ASP A C   1 
ATOM   67    O O   . ASP A 1 18  ? 114.773 118.103 79.600  1.00 65.24  ? 18   ASP A O   1 
ATOM   68    C CB  . ASP A 1 18  ? 115.527 118.373 76.555  1.00 65.24  ? 18   ASP A CB  1 
ATOM   69    C CG  . ASP A 1 18  ? 114.028 118.257 76.368  1.00 65.24  ? 18   ASP A CG  1 
ATOM   70    O OD1 . ASP A 1 18  ? 113.596 117.624 75.383  1.00 65.24  ? 18   ASP A OD1 1 
ATOM   71    O OD2 . ASP A 1 18  ? 113.280 118.812 77.200  1.00 65.24  ? 18   ASP A OD2 1 
ATOM   72    N N   . ALA A 1 19  ? 117.002 117.770 79.465  1.00 54.51  ? 19   ALA A N   1 
ATOM   73    C CA  . ALA A 1 19  ? 117.110 116.927 80.646  1.00 54.51  ? 19   ALA A CA  1 
ATOM   74    C C   . ALA A 1 19  ? 117.355 117.728 81.918  1.00 54.51  ? 19   ALA A C   1 
ATOM   75    O O   . ALA A 1 19  ? 117.851 117.178 82.903  1.00 54.51  ? 19   ALA A O   1 
ATOM   76    C CB  . ALA A 1 19  ? 118.221 115.893 80.450  1.00 54.51  ? 19   ALA A CB  1 
ATOM   77    N N   . PHE A 1 20  ? 117.010 119.007 81.924  1.00 61.02  ? 20   PHE A N   1 
ATOM   78    C CA  . PHE A 1 20  ? 117.054 119.809 83.137  1.00 61.02  ? 20   PHE A CA  1 
ATOM   79    C C   . PHE A 1 20  ? 115.757 119.535 83.906  1.00 61.02  ? 20   PHE A C   1 
ATOM   80    O O   . PHE A 1 20  ? 114.895 118.767 83.464  1.00 61.02  ? 20   PHE A O   1 
ATOM   81    C CB  . PHE A 1 20  ? 117.330 121.267 82.740  1.00 61.02  ? 20   PHE A CB  1 
ATOM   82    C CG  . PHE A 1 20  ? 117.501 122.240 83.895  1.00 61.02  ? 20   PHE A CG  1 
ATOM   83    C CD1 . PHE A 1 20  ? 118.762 122.512 84.401  1.00 61.02  ? 20   PHE A CD1 1 
ATOM   84    C CD2 . PHE A 1 20  ? 116.434 123.014 84.343  1.00 61.02  ? 20   PHE A CD2 1 
ATOM   85    C CE1 . PHE A 1 20  ? 118.933 123.426 85.432  1.00 61.02  ? 20   PHE A CE1 1 
ATOM   86    C CE2 . PHE A 1 20  ? 116.596 123.931 85.370  1.00 61.02  ? 20   PHE A CE2 1 
ATOM   87    C CZ  . PHE A 1 20  ? 117.848 124.143 85.909  1.00 61.02  ? 20   PHE A CZ  1 
ATOM   88    N N   . VAL A 1 21  ? 115.680 120.068 85.129  1.00 65.19  ? 21   VAL A N   1 
ATOM   89    C CA  . VAL A 1 21  ? 114.444 120.171 85.896  1.00 65.19  ? 21   VAL A CA  1 
ATOM   90    C C   . VAL A 1 21  ? 113.330 120.727 85.024  1.00 65.19  ? 21   VAL A C   1 
ATOM   91    O O   . VAL A 1 21  ? 113.495 121.753 84.354  1.00 65.19  ? 21   VAL A O   1 
ATOM   92    C CB  . VAL A 1 21  ? 114.684 121.068 87.125  1.00 65.19  ? 21   VAL A CB  1 
ATOM   93    C CG1 . VAL A 1 21  ? 113.407 121.287 87.915  1.00 65.19  ? 21   VAL A CG1 1 
ATOM   94    C CG2 . VAL A 1 21  ? 115.789 120.495 87.988  1.00 65.19  ? 21   VAL A CG2 1 
ATOM   95    N N   . ASP A 1 22  ? 112.189 120.046 85.023  1.00 71.83  ? 22   ASP A N   1 
ATOM   96    C CA  . ASP A 1 22  ? 111.088 120.463 84.171  1.00 71.83  ? 22   ASP A CA  1 
ATOM   97    C C   . ASP A 1 22  ? 109.968 121.000 85.047  1.00 71.83  ? 22   ASP A C   1 
ATOM   98    O O   . ASP A 1 22  ? 108.794 120.660 84.863  1.00 71.83  ? 22   ASP A O   1 
ATOM   99    C CB  . ASP A 1 22  ? 110.600 119.314 83.295  1.00 71.83  ? 22   ASP A CB  1 
ATOM   100   C CG  . ASP A 1 22  ? 109.996 119.800 81.997  1.00 71.83  ? 22   ASP A CG  1 
ATOM   101   O OD1 . ASP A 1 22  ? 110.206 120.985 81.663  1.00 71.83  ? 22   ASP A OD1 1 
ATOM   102   O OD2 . ASP A 1 22  ? 109.315 119.011 81.312  1.00 71.83  ? 22   ASP A OD2 1 
ATOM   103   N N   . TYR A 1 23  ? 110.344 121.845 86.013  1.00 73.32  ? 23   TYR A N   1 
ATOM   104   C CA  . TYR A 1 23  ? 109.382 122.487 86.899  1.00 73.32  ? 23   TYR A CA  1 
ATOM   105   C C   . TYR A 1 23  ? 108.512 123.501 86.168  1.00 73.32  ? 23   TYR A C   1 
ATOM   106   O O   . TYR A 1 23  ? 107.516 123.956 86.733  1.00 73.32  ? 23   TYR A O   1 
ATOM   107   C CB  . TYR A 1 23  ? 110.123 123.138 88.082  1.00 73.32  ? 23   TYR A CB  1 
ATOM   108   C CG  . TYR A 1 23  ? 110.789 124.492 87.831  1.00 73.32  ? 23   TYR A CG  1 
ATOM   109   C CD1 . TYR A 1 23  ? 112.134 124.572 87.488  1.00 73.32  ? 23   TYR A CD1 1 
ATOM   110   C CD2 . TYR A 1 23  ? 110.104 125.691 88.055  1.00 73.32  ? 23   TYR A CD2 1 
ATOM   111   C CE1 . TYR A 1 23  ? 112.752 125.792 87.285  1.00 73.32  ? 23   TYR A CE1 1 
ATOM   112   C CE2 . TYR A 1 23  ? 110.715 126.914 87.853  1.00 73.32  ? 23   TYR A CE2 1 
ATOM   113   C CZ  . TYR A 1 23  ? 112.039 126.958 87.474  1.00 73.32  ? 23   TYR A CZ  1 
ATOM   114   O OH  . TYR A 1 23  ? 112.651 128.174 87.283  1.00 73.32  ? 23   TYR A OH  1 
ATOM   115   N N   . SER A 1 24  ? 108.891 123.900 84.954  1.00 70.58  ? 24   SER A N   1 
ATOM   116   C CA  . SER A 1 24  ? 108.072 124.771 84.123  1.00 70.58  ? 24   SER A CA  1 
ATOM   117   C C   . SER A 1 24  ? 106.941 124.003 83.448  1.00 70.58  ? 24   SER A C   1 
ATOM   118   O O   . SER A 1 24  ? 105.767 124.358 83.597  1.00 70.58  ? 24   SER A O   1 
ATOM   119   C CB  . SER A 1 24  ? 108.941 125.458 83.068  1.00 70.58  ? 24   SER A CB  1 
ATOM   120   O OG  . SER A 1 24  ? 109.482 124.507 82.167  1.00 70.58  ? 24   SER A OG  1 
ATOM   121   N N   . GLN A 1 25  ? 107.289 122.945 82.707  1.00 70.80  ? 25   GLN A N   1 
ATOM   122   C CA  . GLN A 1 25  ? 106.339 122.340 81.779  1.00 70.80  ? 25   GLN A CA  1 
ATOM   123   C C   . GLN A 1 25  ? 105.291 121.495 82.488  1.00 70.80  ? 25   GLN A C   1 
ATOM   124   O O   . GLN A 1 25  ? 104.145 121.423 82.028  1.00 70.80  ? 25   GLN A O   1 
ATOM   125   C CB  . GLN A 1 25  ? 107.082 121.490 80.746  1.00 70.80  ? 25   GLN A CB  1 
ATOM   126   C CG  . GLN A 1 25  ? 106.352 121.308 79.417  1.00 70.80  ? 25   GLN A CG  1 
ATOM   127   C CD  . GLN A 1 25  ? 105.397 120.126 79.412  1.00 70.80  ? 25   GLN A CD  1 
ATOM   128   O OE1 . GLN A 1 25  ? 105.807 118.981 79.598  1.00 70.80  ? 25   GLN A OE1 1 
ATOM   129   N NE2 . GLN A 1 25  ? 104.116 120.401 79.197  1.00 70.80  ? 25   GLN A NE2 1 
ATOM   130   N N   . LEU A 1 26  ? 105.650 120.857 83.602  1.00 69.80  ? 26   LEU A N   1 
ATOM   131   C CA  . LEU A 1 26  ? 104.756 119.872 84.201  1.00 69.80  ? 26   LEU A CA  1 
ATOM   132   C C   . LEU A 1 26  ? 103.616 120.542 84.961  1.00 69.80  ? 26   LEU A C   1 
ATOM   133   O O   . LEU A 1 26  ? 102.501 120.011 85.020  1.00 69.80  ? 26   LEU A O   1 
ATOM   134   C CB  . LEU A 1 26  ? 105.545 118.927 85.110  1.00 69.80  ? 26   LEU A CB  1 
ATOM   135   C CG  . LEU A 1 26  ? 106.025 117.580 84.546  1.00 69.80  ? 26   LEU A CG  1 
ATOM   136   C CD1 . LEU A 1 26  ? 106.599 117.682 83.135  1.00 69.80  ? 26   LEU A CD1 1 
ATOM   137   C CD2 . LEU A 1 26  ? 107.038 116.942 85.485  1.00 69.80  ? 26   LEU A CD2 1 
ATOM   138   N N   . LYS A 1 27  ? 103.869 121.715 85.544  1.00 75.83  ? 27   LYS A N   1 
ATOM   139   C CA  . LYS A 1 27  ? 102.840 122.351 86.356  1.00 75.83  ? 27   LYS A CA  1 
ATOM   140   C C   . LYS A 1 27  ? 101.783 123.058 85.521  1.00 75.83  ? 27   LYS A C   1 
ATOM   141   O O   . LYS A 1 27  ? 100.666 123.256 86.008  1.00 75.83  ? 27   LYS A O   1 
ATOM   142   C CB  . LYS A 1 27  ? 103.454 123.357 87.330  1.00 75.83  ? 27   LYS A CB  1 
ATOM   143   C CG  . LYS A 1 27  ? 104.331 124.397 86.679  1.00 75.83  ? 27   LYS A CG  1 
ATOM   144   C CD  . LYS A 1 27  ? 104.693 125.508 87.657  1.00 75.83  ? 27   LYS A CD  1 
ATOM   145   C CE  . LYS A 1 27  ? 103.458 126.134 88.290  1.00 75.83  ? 27   LYS A CE  1 
ATOM   146   N NZ  . LYS A 1 27  ? 103.813 127.257 89.202  1.00 75.83  ? 27   LYS A NZ  1 
ATOM   147   N N   . LYS A 1 28  ? 102.100 123.459 84.288  1.00 67.83  ? 28   LYS A N   1 
ATOM   148   C CA  . LYS A 1 28  ? 101.060 124.066 83.466  1.00 67.83  ? 28   LYS A CA  1 
ATOM   149   C C   . LYS A 1 28  ? 100.146 123.003 82.870  1.00 67.83  ? 28   LYS A C   1 
ATOM   150   O O   . LYS A 1 28  ? 99.003  123.302 82.507  1.00 67.83  ? 28   LYS A O   1 
ATOM   151   C CB  . LYS A 1 28  ? 101.668 124.957 82.380  1.00 67.83  ? 28   LYS A CB  1 
ATOM   152   C CG  . LYS A 1 28  ? 102.260 124.252 81.173  1.00 67.83  ? 28   LYS A CG  1 
ATOM   153   C CD  . LYS A 1 28  ? 103.500 124.985 80.686  1.00 67.83  ? 28   LYS A CD  1 
ATOM   154   C CE  . LYS A 1 28  ? 104.152 124.276 79.516  1.00 67.83  ? 28   LYS A CE  1 
ATOM   155   N NZ  . LYS A 1 28  ? 105.519 124.806 79.257  1.00 67.83  ? 28   LYS A NZ  1 
ATOM   156   N N   . ASP A 1 29  ? 100.626 121.762 82.770  1.00 67.72  ? 29   ASP A N   1 
ATOM   157   C CA  . ASP A 1 29  ? 99.723  120.637 82.575  1.00 67.72  ? 29   ASP A CA  1 
ATOM   158   C C   . ASP A 1 29  ? 98.941  120.338 83.843  1.00 67.72  ? 29   ASP A C   1 
ATOM   159   O O   . ASP A 1 29  ? 97.788  119.902 83.760  1.00 67.72  ? 29   ASP A O   1 
ATOM   160   C CB  . ASP A 1 29  ? 100.503 119.404 82.129  1.00 67.72  ? 29   ASP A CB  1 
ATOM   161   C CG  . ASP A 1 29  ? 101.522 119.725 81.062  1.00 67.72  ? 29   ASP A CG  1 
ATOM   162   O OD1 . ASP A 1 29  ? 101.271 120.652 80.265  1.00 67.72  ? 29   ASP A OD1 1 
ATOM   163   O OD2 . ASP A 1 29  ? 102.573 119.054 81.018  1.00 67.72  ? 29   ASP A OD2 1 
ATOM   164   N N   . LEU A 1 30  ? 99.541  120.575 85.013  1.00 68.14  ? 30   LEU A N   1 
ATOM   165   C CA  . LEU A 1 30  ? 98.778  120.525 86.254  1.00 68.14  ? 30   LEU A CA  1 
ATOM   166   C C   . LEU A 1 30  ? 97.871  121.744 86.383  1.00 68.14  ? 30   LEU A C   1 
ATOM   167   O O   . LEU A 1 30  ? 96.869  121.697 87.105  1.00 68.14  ? 30   LEU A O   1 
ATOM   168   C CB  . LEU A 1 30  ? 99.732  120.400 87.448  1.00 68.14  ? 30   LEU A CB  1 
ATOM   169   C CG  . LEU A 1 30  ? 99.207  119.929 88.813  1.00 68.14  ? 30   LEU A CG  1 
ATOM   170   C CD1 . LEU A 1 30  ? 100.278 119.103 89.510  1.00 68.14  ? 30   LEU A CD1 1 
ATOM   171   C CD2 . LEU A 1 30  ? 98.795  121.088 89.712  1.00 68.14  ? 30   LEU A CD2 1 
ATOM   172   N N   . LYS A 1 31  ? 98.191  122.839 85.688  1.00 81.45  ? 31   LYS A N   1 
ATOM   173   C CA  . LYS A 1 31  ? 97.198  123.889 85.500  1.00 81.45  ? 31   LYS A CA  1 
ATOM   174   C C   . LYS A 1 31  ? 96.111  123.460 84.520  1.00 81.45  ? 31   LYS A C   1 
ATOM   175   O O   . LYS A 1 31  ? 95.018  124.034 84.533  1.00 81.45  ? 31   LYS A O   1 
ATOM   176   C CB  . LYS A 1 31  ? 97.848  125.179 84.981  1.00 81.45  ? 31   LYS A CB  1 
ATOM   177   C CG  . LYS A 1 31  ? 97.119  126.484 85.346  1.00 81.45  ? 31   LYS A CG  1 
ATOM   178   C CD  . LYS A 1 31  ? 97.120  126.820 86.840  1.00 81.45  ? 31   LYS A CD  1 
ATOM   179   C CE  . LYS A 1 31  ? 98.519  127.209 87.381  1.00 81.45  ? 31   LYS A CE  1 
ATOM   180   N NZ  . LYS A 1 31  ? 98.371  127.541 88.851  1.00 81.45  ? 31   LYS A NZ  1 
ATOM   181   N N   . LYS A 1 32  ? 96.389  122.476 83.662  1.00 67.07  ? 32   LYS A N   1 
ATOM   182   C CA  . LYS A 1 32  ? 95.411  122.070 82.661  1.00 67.07  ? 32   LYS A CA  1 
ATOM   183   C C   . LYS A 1 32  ? 94.438  121.017 83.178  1.00 67.07  ? 32   LYS A C   1 
ATOM   184   O O   . LYS A 1 32  ? 93.334  120.896 82.637  1.00 67.07  ? 32   LYS A O   1 
ATOM   185   C CB  . LYS A 1 32  ? 96.120  121.568 81.401  1.00 67.07  ? 32   LYS A CB  1 
ATOM   186   C CG  . LYS A 1 32  ? 95.285  121.716 80.130  1.00 67.07  ? 32   LYS A CG  1 
ATOM   187   C CD  . LYS A 1 32  ? 96.133  121.925 78.879  1.00 67.07  ? 32   LYS A CD  1 
ATOM   188   C CE  . LYS A 1 32  ? 97.352  121.015 78.839  1.00 67.07  ? 32   LYS A CE  1 
ATOM   189   N NZ  . LYS A 1 32  ? 97.924  120.931 77.469  1.00 67.07  ? 32   LYS A NZ  1 
ATOM   190   N N   . ILE A 1 33  ? 94.806  120.254 84.206  1.00 68.96  ? 33   ILE A N   1 
ATOM   191   C CA  . ILE A 1 33  ? 93.798  119.430 84.866  1.00 68.96  ? 33   ILE A CA  1 
ATOM   192   C C   . ILE A 1 33  ? 92.940  120.311 85.780  1.00 68.96  ? 33   ILE A C   1 
ATOM   193   O O   . ILE A 1 33  ? 91.775  119.990 86.056  1.00 68.96  ? 33   ILE A O   1 
ATOM   194   C CB  . ILE A 1 33  ? 94.478  118.254 85.604  1.00 68.96  ? 33   ILE A CB  1 
ATOM   195   C CG1 . ILE A 1 33  ? 93.458  117.292 86.231  1.00 68.96  ? 33   ILE A CG1 1 
ATOM   196   C CG2 . ILE A 1 33  ? 95.453  118.751 86.659  1.00 68.96  ? 33   ILE A CG2 1 
ATOM   197   C CD1 . ILE A 1 33  ? 93.960  115.871 86.376  1.00 68.96  ? 33   ILE A CD1 1 
ATOM   198   N N   . HIS A 1 34  ? 93.481  121.457 86.207  1.00 68.78  ? 34   HIS A N   1 
ATOM   199   C CA  . HIS A 1 34  ? 92.750  122.431 87.009  1.00 68.78  ? 34   HIS A CA  1 
ATOM   200   C C   . HIS A 1 34  ? 91.583  123.050 86.244  1.00 68.78  ? 34   HIS A C   1 
ATOM   201   O O   . HIS A 1 34  ? 90.529  123.308 86.835  1.00 68.78  ? 34   HIS A O   1 
ATOM   202   C CB  . HIS A 1 34  ? 93.716  123.519 87.483  1.00 68.78  ? 34   HIS A CB  1 
ATOM   203   C CG  . HIS A 1 34  ? 93.202  124.350 88.617  1.00 68.78  ? 34   HIS A CG  1 
ATOM   204   N ND1 . HIS A 1 34  ? 93.900  125.430 89.115  1.00 68.78  ? 34   HIS A ND1 1 
ATOM   205   C CD2 . HIS A 1 34  ? 92.077  124.253 89.363  1.00 68.78  ? 34   HIS A CD2 1 
ATOM   206   C CE1 . HIS A 1 34  ? 93.219  125.970 90.110  1.00 68.78  ? 34   HIS A CE1 1 
ATOM   207   N NE2 . HIS A 1 34  ? 92.109  125.274 90.281  1.00 68.78  ? 34   HIS A NE2 1 
ATOM   208   N N   . LEU A 1 35  ? 91.737  123.275 84.935  1.00 66.23  ? 35   LEU A N   1 
ATOM   209   C CA  . LEU A 1 35  ? 90.628  123.806 84.146  1.00 66.23  ? 35   LEU A CA  1 
ATOM   210   C C   . LEU A 1 35  ? 89.649  122.709 83.745  1.00 66.23  ? 35   LEU A C   1 
ATOM   211   O O   . LEU A 1 35  ? 88.567  123.005 83.226  1.00 66.23  ? 35   LEU A O   1 
ATOM   212   C CB  . LEU A 1 35  ? 91.159  124.548 82.914  1.00 66.23  ? 35   LEU A CB  1 
ATOM   213   C CG  . LEU A 1 35  ? 92.106  123.866 81.917  1.00 66.23  ? 35   LEU A CG  1 
ATOM   214   C CD1 . LEU A 1 35  ? 91.370  123.219 80.742  1.00 66.23  ? 35   LEU A CD1 1 
ATOM   215   C CD2 . LEU A 1 35  ? 93.155  124.849 81.417  1.00 66.23  ? 35   LEU A CD2 1 
ATOM   216   N N   . PHE A 1 36  ? 90.012  121.445 83.966  1.00 67.31  ? 36   PHE A N   1 
ATOM   217   C CA  . PHE A 1 36  ? 89.089  120.340 83.753  1.00 67.31  ? 36   PHE A CA  1 
ATOM   218   C C   . PHE A 1 36  ? 88.217  120.082 84.978  1.00 67.31  ? 36   PHE A C   1 
ATOM   219   O O   . PHE A 1 36  ? 87.176  119.425 84.860  1.00 67.31  ? 36   PHE A O   1 
ATOM   220   C CB  . PHE A 1 36  ? 89.881  119.081 83.369  1.00 67.31  ? 36   PHE A CB  1 
ATOM   221   C CG  . PHE A 1 36  ? 89.024  117.898 82.997  1.00 67.31  ? 36   PHE A CG  1 
ATOM   222   C CD1 . PHE A 1 36  ? 88.366  117.855 81.775  1.00 67.31  ? 36   PHE A CD1 1 
ATOM   223   C CD2 . PHE A 1 36  ? 88.877  116.832 83.871  1.00 67.31  ? 36   PHE A CD2 1 
ATOM   224   C CE1 . PHE A 1 36  ? 87.573  116.767 81.429  1.00 67.31  ? 36   PHE A CE1 1 
ATOM   225   C CE2 . PHE A 1 36  ? 88.087  115.741 83.535  1.00 67.31  ? 36   PHE A CE2 1 
ATOM   226   C CZ  . PHE A 1 36  ? 87.436  115.711 82.312  1.00 67.31  ? 36   PHE A CZ  1 
ATOM   227   N N   . THR A 1 37  ? 88.598  120.623 86.139  1.00 64.70  ? 37   THR A N   1 
ATOM   228   C CA  . THR A 1 37  ? 87.866  120.372 87.376  1.00 64.70  ? 37   THR A CA  1 
ATOM   229   C C   . THR A 1 37  ? 86.507  121.062 87.365  1.00 64.70  ? 37   THR A C   1 
ATOM   230   O O   . THR A 1 37  ? 85.487  120.453 87.708  1.00 64.70  ? 37   THR A O   1 
ATOM   231   C CB  . THR A 1 37  ? 88.696  120.844 88.574  1.00 64.70  ? 37   THR A CB  1 
ATOM   232   O OG1 . THR A 1 37  ? 89.975  120.200 88.552  1.00 64.70  ? 37   THR A OG1 1 
ATOM   233   C CG2 . THR A 1 37  ? 87.998  120.505 89.883  1.00 64.70  ? 37   THR A CG2 1 
ATOM   234   N N   . ASN A 1 38  ? 86.472  122.327 86.945  1.00 64.39  ? 38   ASN A N   1 
ATOM   235   C CA  . ASN A 1 38  ? 85.201  123.031 86.849  1.00 64.39  ? 38   ASN A CA  1 
ATOM   236   C C   . ASN A 1 38  ? 84.534  122.800 85.499  1.00 64.39  ? 38   ASN A C   1 
ATOM   237   O O   . ASN A 1 38  ? 83.327  123.028 85.360  1.00 64.39  ? 38   ASN A O   1 
ATOM   238   C CB  . ASN A 1 38  ? 85.375  124.535 87.101  1.00 64.39  ? 38   ASN A CB  1 
ATOM   239   C CG  . ASN A 1 38  ? 85.687  124.883 88.557  1.00 64.39  ? 38   ASN A CG  1 
ATOM   240   O OD1 . ASN A 1 38  ? 85.390  124.133 89.486  1.00 64.39  ? 38   ASN A OD1 1 
ATOM   241   N ND2 . ASN A 1 38  ? 86.291  126.049 88.751  1.00 64.39  ? 38   ASN A ND2 1 
ATOM   242   N N   . GLY A 1 39  ? 85.294  122.360 84.501  1.00 55.34  ? 39   GLY A N   1 
ATOM   243   C CA  . GLY A 1 39  ? 84.752  122.119 83.177  1.00 55.34  ? 39   GLY A CA  1 
ATOM   244   C C   . GLY A 1 39  ? 83.978  120.820 83.063  1.00 55.34  ? 39   GLY A C   1 
ATOM   245   O O   . GLY A 1 39  ? 83.001  120.601 83.779  1.00 55.34  ? 39   GLY A O   1 
ATOM   246   N N   . VAL A 1 73  ? 96.852  107.359 94.458  1.00 62.84  ? 73   VAL A N   1 
ATOM   247   C CA  . VAL A 1 73  ? 96.123  107.712 93.249  1.00 62.84  ? 73   VAL A CA  1 
ATOM   248   C C   . VAL A 1 73  ? 96.536  106.727 92.147  1.00 62.84  ? 73   VAL A C   1 
ATOM   249   O O   . VAL A 1 73  ? 95.811  106.508 91.175  1.00 62.84  ? 73   VAL A O   1 
ATOM   250   C CB  . VAL A 1 73  ? 96.375  109.202 92.861  1.00 62.84  ? 73   VAL A CB  1 
ATOM   251   C CG1 . VAL A 1 73  ? 97.850  109.459 92.566  1.00 62.84  ? 73   VAL A CG1 1 
ATOM   252   C CG2 . VAL A 1 73  ? 95.462  109.670 91.722  1.00 62.84  ? 73   VAL A CG2 1 
ATOM   253   N N   . ILE A 1 74  ? 97.699  106.103 92.325  1.00 63.01  ? 74   ILE A N   1 
ATOM   254   C CA  . ILE A 1 74  ? 98.209  105.152 91.345  1.00 63.01  ? 74   ILE A CA  1 
ATOM   255   C C   . ILE A 1 74  ? 98.977  104.041 92.054  1.00 63.01  ? 74   ILE A C   1 
ATOM   256   O O   . ILE A 1 74  ? 99.722  104.295 93.007  1.00 63.01  ? 74   ILE A O   1 
ATOM   257   C CB  . ILE A 1 74  ? 99.080  105.877 90.291  1.00 63.01  ? 74   ILE A CB  1 
ATOM   258   C CG1 . ILE A 1 74  ? 99.740  104.887 89.320  1.00 63.01  ? 74   ILE A CG1 1 
ATOM   259   C CG2 . ILE A 1 74  ? 100.098 106.807 90.955  1.00 63.01  ? 74   ILE A CG2 1 
ATOM   260   C CD1 . ILE A 1 74  ? 100.538 105.509 88.212  1.00 63.01  ? 74   ILE A CD1 1 
ATOM   261   N N   . GLN A 1 75  ? 98.781  102.796 91.618  1.00 65.29  ? 75   GLN A N   1 
ATOM   262   C CA  . GLN A 1 75  ? 99.746  101.741 91.898  1.00 65.29  ? 75   GLN A CA  1 
ATOM   263   C C   . GLN A 1 75  ? 100.629 101.611 90.662  1.00 65.29  ? 75   GLN A C   1 
ATOM   264   O O   . GLN A 1 75  ? 100.136 101.620 89.529  1.00 65.29  ? 75   GLN A O   1 
ATOM   265   C CB  . GLN A 1 75  ? 99.063  100.417 92.300  1.00 65.29  ? 75   GLN A CB  1 
ATOM   266   C CG  . GLN A 1 75  ? 98.454  99.538  91.209  1.00 65.29  ? 75   GLN A CG  1 
ATOM   267   C CD  . GLN A 1 75  ? 97.795  98.290  91.766  1.00 65.29  ? 75   GLN A CD  1 
ATOM   268   O OE1 . GLN A 1 75  ? 98.157  97.809  92.840  1.00 65.29  ? 75   GLN A OE1 1 
ATOM   269   N NE2 . GLN A 1 75  ? 96.823  97.758  91.036  1.00 65.29  ? 75   GLN A NE2 1 
ATOM   270   N N   . VAL A 1 76  ? 101.942 101.591 90.878  1.00 67.01  ? 76   VAL A N   1 
ATOM   271   C CA  . VAL A 1 76  ? 102.887 101.725 89.773  1.00 67.01  ? 76   VAL A CA  1 
ATOM   272   C C   . VAL A 1 76  ? 103.204 100.337 89.227  1.00 67.01  ? 76   VAL A C   1 
ATOM   273   O O   . VAL A 1 76  ? 103.668 99.461  89.962  1.00 67.01  ? 76   VAL A O   1 
ATOM   274   C CB  . VAL A 1 76  ? 104.160 102.458 90.205  1.00 67.01  ? 76   VAL A CB  1 
ATOM   275   C CG1 . VAL A 1 76  ? 105.002 102.791 88.984  1.00 67.01  ? 76   VAL A CG1 1 
ATOM   276   C CG2 . VAL A 1 76  ? 103.812 103.719 90.983  1.00 67.01  ? 76   VAL A CG2 1 
ATOM   277   N N   . HIS A 1 77  ? 102.953 100.138 87.936  1.00 69.66  ? 77   HIS A N   1 
ATOM   278   C CA  . HIS A 1 77  ? 103.302 98.899  87.245  1.00 69.66  ? 77   HIS A CA  1 
ATOM   279   C C   . HIS A 1 77  ? 104.770 98.978  86.846  1.00 69.66  ? 77   HIS A C   1 
ATOM   280   O O   . HIS A 1 77  ? 105.120 99.436  85.759  1.00 69.66  ? 77   HIS A O   1 
ATOM   281   C CB  . HIS A 1 77  ? 102.400 98.687  86.037  1.00 69.66  ? 77   HIS A CB  1 
ATOM   282   C CG  . HIS A 1 77  ? 100.988 98.340  86.390  1.00 69.66  ? 77   HIS A CG  1 
ATOM   283   N ND1 . HIS A 1 77  ? 100.489 97.060  86.285  1.00 69.66  ? 77   HIS A ND1 1 
ATOM   284   C CD2 . HIS A 1 77  ? 99.970  99.105  86.851  1.00 69.66  ? 77   HIS A CD2 1 
ATOM   285   C CE1 . HIS A 1 77  ? 99.224  97.050  86.665  1.00 69.66  ? 77   HIS A CE1 1 
ATOM   286   N NE2 . HIS A 1 77  ? 98.884  98.279  87.013  1.00 69.66  ? 77   HIS A NE2 1 
ATOM   287   N N   . LYS A 1 78  ? 105.637 98.526  87.748  1.00 70.72  ? 78   LYS A N   1 
ATOM   288   C CA  . LYS A 1 78  ? 107.077 98.591  87.544  1.00 70.72  ? 78   LYS A CA  1 
ATOM   289   C C   . LYS A 1 78  ? 107.523 97.573  86.503  1.00 70.72  ? 78   LYS A C   1 
ATOM   290   O O   . LYS A 1 78  ? 107.558 96.369  86.777  1.00 70.72  ? 78   LYS A O   1 
ATOM   291   C CB  . LYS A 1 78  ? 107.803 98.329  88.864  1.00 70.72  ? 78   LYS A CB  1 
ATOM   292   C CG  . LYS A 1 78  ? 109.177 98.958  88.983  1.00 70.72  ? 78   LYS A CG  1 
ATOM   293   C CD  . LYS A 1 78  ? 109.434 99.413  90.407  1.00 70.72  ? 78   LYS A CD  1 
ATOM   294   C CE  . LYS A 1 78  ? 110.609 100.365 90.486  1.00 70.72  ? 78   LYS A CE  1 
ATOM   295   N NZ  . LYS A 1 78  ? 110.663 101.022 91.817  1.00 70.72  ? 78   LYS A NZ  1 
ATOM   296   N N   . LYS A 1 79  ? 107.869 98.054  85.311  1.00 76.50  ? 79   LYS A N   1 
ATOM   297   C CA  . LYS A 1 79  ? 108.455 97.191  84.294  1.00 76.50  ? 79   LYS A CA  1 
ATOM   298   C C   . LYS A 1 79  ? 109.701 97.865  83.745  1.00 76.50  ? 79   LYS A C   1 
ATOM   299   O O   . LYS A 1 79  ? 109.691 99.052  83.406  1.00 76.50  ? 79   LYS A O   1 
ATOM   300   C CB  . LYS A 1 79  ? 107.483 96.881  83.147  1.00 76.50  ? 79   LYS A CB  1 
ATOM   301   C CG  . LYS A 1 79  ? 106.108 96.382  83.550  1.00 76.50  ? 79   LYS A CG  1 
ATOM   302   C CD  . LYS A 1 79  ? 105.160 96.415  82.363  1.00 76.50  ? 79   LYS A CD  1 
ATOM   303   C CE  . LYS A 1 79  ? 104.794 97.837  81.986  1.00 76.50  ? 79   LYS A CE  1 
ATOM   304   N NZ  . LYS A 1 79  ? 103.909 97.884  80.791  1.00 76.50  ? 79   LYS A NZ  1 
ATOM   305   N N   . LEU A 1 80  ? 110.776 97.091  83.664  1.00 75.50  ? 80   LEU A N   1 
ATOM   306   C CA  . LEU A 1 80  ? 112.005 97.528  83.029  1.00 75.50  ? 80   LEU A CA  1 
ATOM   307   C C   . LEU A 1 80  ? 111.916 97.248  81.531  1.00 75.50  ? 80   LEU A C   1 
ATOM   308   O O   . LEU A 1 80  ? 110.883 96.805  81.020  1.00 75.50  ? 80   LEU A O   1 
ATOM   309   C CB  . LEU A 1 80  ? 113.212 96.847  83.680  1.00 75.50  ? 80   LEU A CB  1 
ATOM   310   C CG  . LEU A 1 80  ? 114.024 97.681  84.675  1.00 75.50  ? 80   LEU A CG  1 
ATOM   311   C CD1 . LEU A 1 80  ? 113.179 98.093  85.869  1.00 75.50  ? 80   LEU A CD1 1 
ATOM   312   C CD2 . LEU A 1 80  ? 115.259 96.917  85.127  1.00 75.50  ? 80   LEU A CD2 1 
ATOM   313   N N   . ALA A 1 81  ? 113.006 97.502  80.815  1.00 68.09  ? 81   ALA A N   1 
ATOM   314   C CA  . ALA A 1 81  ? 113.002 97.376  79.365  1.00 68.09  ? 81   ALA A CA  1 
ATOM   315   C C   . ALA A 1 81  ? 113.031 95.913  78.942  1.00 68.09  ? 81   ALA A C   1 
ATOM   316   O O   . ALA A 1 81  ? 113.752 95.096  79.519  1.00 68.09  ? 81   ALA A O   1 
ATOM   317   C CB  . ALA A 1 81  ? 114.194 98.116  78.761  1.00 68.09  ? 81   ALA A CB  1 
ATOM   318   N N   . SER A 1 82  ? 112.231 95.589  77.928  1.00 65.83  ? 82   SER A N   1 
ATOM   319   C CA  . SER A 1 82  ? 112.238 94.268  77.312  1.00 65.83  ? 82   SER A CA  1 
ATOM   320   C C   . SER A 1 82  ? 113.334 94.120  76.265  1.00 65.83  ? 82   SER A C   1 
ATOM   321   O O   . SER A 1 82  ? 113.465 93.044  75.671  1.00 65.83  ? 82   SER A O   1 
ATOM   322   C CB  . SER A 1 82  ? 110.877 93.972  76.673  1.00 65.83  ? 82   SER A CB  1 
ATOM   323   O OG  . SER A 1 82  ? 110.638 94.821  75.564  1.00 65.83  ? 82   SER A OG  1 
ATOM   324   N N   . SER A 1 83  ? 114.112 95.173  76.022  1.00 71.83  ? 83   SER A N   1 
ATOM   325   C CA  . SER A 1 83  ? 115.229 95.144  75.093  1.00 71.83  ? 83   SER A CA  1 
ATOM   326   C C   . SER A 1 83  ? 116.555 94.852  75.784  1.00 71.83  ? 83   SER A C   1 
ATOM   327   O O   . SER A 1 83  ? 117.613 95.216  75.255  1.00 71.83  ? 83   SER A O   1 
ATOM   328   C CB  . SER A 1 83  ? 115.315 96.473  74.339  1.00 71.83  ? 83   SER A CB  1 
ATOM   329   O OG  . SER A 1 83  ? 115.359 97.564  75.244  1.00 71.83  ? 83   SER A OG  1 
ATOM   330   N N   . GLY A 1 84  ? 116.523 94.213  76.952  1.00 68.54  ? 84   GLY A N   1 
ATOM   331   C CA  . GLY A 1 84  ? 117.737 93.950  77.697  1.00 68.54  ? 84   GLY A CA  1 
ATOM   332   C C   . GLY A 1 84  ? 118.369 95.163  78.337  1.00 68.54  ? 84   GLY A C   1 
ATOM   333   O O   . GLY A 1 84  ? 119.548 95.109  78.700  1.00 68.54  ? 84   GLY A O   1 
ATOM   334   N N   . SER A 1 85  ? 117.625 96.252  78.493  1.00 70.06  ? 85   SER A N   1 
ATOM   335   C CA  . SER A 1 85  ? 118.129 97.489  79.069  1.00 70.06  ? 85   SER A CA  1 
ATOM   336   C C   . SER A 1 85  ? 117.371 97.790  80.361  1.00 70.06  ? 85   SER A C   1 
ATOM   337   O O   . SER A 1 85  ? 116.577 96.979  80.847  1.00 70.06  ? 85   SER A O   1 
ATOM   338   C CB  . SER A 1 85  ? 118.012 98.638  78.063  1.00 70.06  ? 85   SER A CB  1 
ATOM   339   O OG  . SER A 1 85  ? 118.171 99.892  78.703  1.00 70.06  ? 85   SER A OG  1 
ATOM   340   N N   . ASN A 1 86  ? 117.626 98.969  80.916  1.00 71.42  ? 86   ASN A N   1 
ATOM   341   C CA  . ASN A 1 86  ? 117.040 99.414  82.174  1.00 71.42  ? 86   ASN A CA  1 
ATOM   342   C C   . ASN A 1 86  ? 116.207 100.673 81.976  1.00 71.42  ? 86   ASN A C   1 
ATOM   343   O O   . ASN A 1 86  ? 116.304 101.637 82.739  1.00 71.42  ? 86   ASN A O   1 
ATOM   344   C CB  . ASN A 1 86  ? 118.125 99.621  83.227  1.00 71.42  ? 86   ASN A CB  1 
ATOM   345   C CG  . ASN A 1 86  ? 119.260 100.511 82.742  1.00 71.42  ? 86   ASN A CG  1 
ATOM   346   O OD1 . ASN A 1 86  ? 119.228 101.047 81.633  1.00 71.42  ? 86   ASN A OD1 1 
ATOM   347   N ND2 . ASN A 1 86  ? 120.277 100.665 83.579  1.00 71.42  ? 86   ASN A ND2 1 
ATOM   348   N N   . ASN A 1 87  ? 115.383 100.682 80.933  1.00 73.64  ? 87   ASN A N   1 
ATOM   349   C CA  . ASN A 1 87  ? 114.493 101.803 80.669  1.00 73.64  ? 87   ASN A CA  1 
ATOM   350   C C   . ASN A 1 87  ? 113.248 101.657 81.535  1.00 73.64  ? 87   ASN A C   1 
ATOM   351   O O   . ASN A 1 87  ? 112.473 100.712 81.359  1.00 73.64  ? 87   ASN A O   1 
ATOM   352   C CB  . ASN A 1 87  ? 114.124 101.848 79.189  1.00 73.64  ? 87   ASN A CB  1 
ATOM   353   C CG  . ASN A 1 87  ? 115.312 102.169 78.304  1.00 73.64  ? 87   ASN A CG  1 
ATOM   354   O OD1 . ASN A 1 87  ? 116.134 103.022 78.635  1.00 73.64  ? 87   ASN A OD1 1 
ATOM   355   N ND2 . ASN A 1 87  ? 115.408 101.483 77.170  1.00 73.64  ? 87   ASN A ND2 1 
ATOM   356   N N   . ASP A 1 88  ? 113.055 102.589 82.463  1.00 66.84  ? 88   ASP A N   1 
ATOM   357   C CA  . ASP A 1 88  ? 111.977 102.483 83.444  1.00 66.84  ? 88   ASP A CA  1 
ATOM   358   C C   . ASP A 1 88  ? 110.667 102.936 82.811  1.00 66.84  ? 88   ASP A C   1 
ATOM   359   O O   . ASP A 1 88  ? 110.209 104.059 83.034  1.00 66.84  ? 88   ASP A O   1 
ATOM   360   C CB  . ASP A 1 88  ? 112.302 103.306 84.685  1.00 66.84  ? 88   ASP A CB  1 
ATOM   361   C CG  . ASP A 1 88  ? 113.472 102.747 85.463  1.00 66.84  ? 88   ASP A CG  1 
ATOM   362   O OD1 . ASP A 1 88  ? 113.504 102.916 86.698  1.00 66.84  ? 88   ASP A OD1 1 
ATOM   363   O OD2 . ASP A 1 88  ? 114.368 102.146 84.837  1.00 66.84  ? 88   ASP A OD2 1 
ATOM   364   N N   . VAL A 1 89  ? 110.042 102.048 82.042  1.00 65.41  ? 89   VAL A N   1 
ATOM   365   C CA  . VAL A 1 89  ? 108.758 102.336 81.399  1.00 65.41  ? 89   VAL A CA  1 
ATOM   366   C C   . VAL A 1 89  ? 107.667 101.939 82.396  1.00 65.41  ? 89   VAL A C   1 
ATOM   367   O O   . VAL A 1 89  ? 107.421 100.763 82.662  1.00 65.41  ? 89   VAL A O   1 
ATOM   368   C CB  . VAL A 1 89  ? 108.623 101.636 80.046  1.00 65.41  ? 89   VAL A CB  1 
ATOM   369   C CG1 . VAL A 1 89  ? 109.310 102.454 78.975  1.00 65.41  ? 89   VAL A CG1 1 
ATOM   370   C CG2 . VAL A 1 89  ? 109.270 100.255 80.075  1.00 65.41  ? 89   VAL A CG2 1 
ATOM   371   N N   . TYR A 1 90  ? 107.013 102.947 82.968  1.00 67.50  ? 90   TYR A N   1 
ATOM   372   C CA  . TYR A 1 90  ? 106.064 102.747 84.064  1.00 67.50  ? 90   TYR A CA  1 
ATOM   373   C C   . TYR A 1 90  ? 104.640 102.854 83.524  1.00 67.50  ? 90   TYR A C   1 
ATOM   374   O O   . TYR A 1 90  ? 104.188 103.919 83.107  1.00 67.50  ? 90   TYR A O   1 
ATOM   375   C CB  . TYR A 1 90  ? 106.330 103.750 85.181  1.00 67.50  ? 90   TYR A CB  1 
ATOM   376   C CG  . TYR A 1 90  ? 107.612 103.472 85.932  1.00 67.50  ? 90   TYR A CG  1 
ATOM   377   C CD1 . TYR A 1 90  ? 107.982 102.172 86.252  1.00 67.50  ? 90   TYR A CD1 1 
ATOM   378   C CD2 . TYR A 1 90  ? 108.460 104.506 86.307  1.00 67.50  ? 90   TYR A CD2 1 
ATOM   379   C CE1 . TYR A 1 90  ? 109.155 101.908 86.933  1.00 67.50  ? 90   TYR A CE1 1 
ATOM   380   C CE2 . TYR A 1 90  ? 109.638 104.252 86.990  1.00 67.50  ? 90   TYR A CE2 1 
ATOM   381   C CZ  . TYR A 1 90  ? 109.978 102.950 87.301  1.00 67.50  ? 90   TYR A CZ  1 
ATOM   382   O OH  . TYR A 1 90  ? 111.148 102.692 87.977  1.00 67.50  ? 90   TYR A OH  1 
ATOM   383   N N   . GLU A 1 91  ? 103.931 101.729 83.531  1.00 77.83  ? 91   GLU A N   1 
ATOM   384   C CA  . GLU A 1 91  ? 102.531 101.699 83.136  1.00 77.83  ? 91   GLU A CA  1 
ATOM   385   C C   . GLU A 1 91  ? 101.654 102.210 84.283  1.00 77.83  ? 91   GLU A C   1 
ATOM   386   O O   . GLU A 1 91  ? 101.900 101.941 85.462  1.00 77.83  ? 91   GLU A O   1 
ATOM   387   C CB  . GLU A 1 91  ? 102.134 100.278 82.722  1.00 77.83  ? 91   GLU A CB  1 
ATOM   388   C CG  . GLU A 1 91  ? 100.674 100.060 82.352  1.00 77.83  ? 91   GLU A CG  1 
ATOM   389   C CD  . GLU A 1 91  ? 100.167 101.089 81.365  1.00 77.83  ? 91   GLU A CD  1 
ATOM   390   O OE1 . GLU A 1 91  ? 100.607 101.053 80.200  1.00 77.83  ? 91   GLU A OE1 1 
ATOM   391   O OE2 . GLU A 1 91  ? 99.332  101.933 81.752  1.00 77.83  ? 91   GLU A OE2 1 
ATOM   392   N N   . THR A 1 92  ? 100.615 102.958 83.922  1.00 76.75  ? 92   THR A N   1 
ATOM   393   C CA  . THR A 1 92  ? 99.756  103.657 84.867  1.00 76.75  ? 92   THR A CA  1 
ATOM   394   C C   . THR A 1 92  ? 98.517  102.826 85.170  1.00 76.75  ? 92   THR A C   1 
ATOM   395   O O   . THR A 1 92  ? 98.140  101.950 84.386  1.00 76.75  ? 92   THR A O   1 
ATOM   396   C CB  . THR A 1 92  ? 99.325  105.000 84.300  1.00 76.75  ? 92   THR A CB  1 
ATOM   397   O OG1 . THR A 1 92  ? 98.193  104.804 83.446  1.00 76.75  ? 92   THR A OG1 1 
ATOM   398   C CG2 . THR A 1 92  ? 100.445 105.568 83.457  1.00 76.75  ? 92   THR A CG2 1 
ATOM   399   N N   . GLU A 1 93  ? 97.882  103.104 86.307  1.00 74.92  ? 93   GLU A N   1 
ATOM   400   C CA  . GLU A 1 93  ? 96.586  102.522 86.644  1.00 74.92  ? 93   GLU A CA  1 
ATOM   401   C C   . GLU A 1 93  ? 95.802  103.495 87.511  1.00 74.92  ? 93   GLU A C   1 
ATOM   402   O O   . GLU A 1 93  ? 96.319  103.990 88.519  1.00 74.92  ? 93   GLU A O   1 
ATOM   403   C CB  . GLU A 1 93  ? 96.724  101.176 87.359  1.00 74.92  ? 93   GLU A CB  1 
ATOM   404   C CG  . GLU A 1 93  ? 95.697  100.156 86.884  1.00 74.92  ? 93   GLU A CG  1 
ATOM   405   C CD  . GLU A 1 93  ? 95.692  98.887  87.708  1.00 74.92  ? 93   GLU A CD  1 
ATOM   406   O OE1 . GLU A 1 93  ? 95.047  98.883  88.779  1.00 74.92  ? 93   GLU A OE1 1 
ATOM   407   O OE2 . GLU A 1 93  ? 96.309  97.892  87.285  1.00 74.92  ? 93   GLU A OE2 1 
ATOM   408   N N   . LEU A 1 94  ? 94.558  103.767 87.117  1.00 73.17  ? 94   LEU A N   1 
ATOM   409   C CA  . LEU A 1 94  ? 93.638  104.592 87.898  1.00 73.17  ? 94   LEU A CA  1 
ATOM   410   C C   . LEU A 1 94  ? 92.669  103.656 88.615  1.00 73.17  ? 94   LEU A C   1 
ATOM   411   O O   . LEU A 1 94  ? 92.091  102.753 88.004  1.00 73.17  ? 94   LEU A O   1 
ATOM   412   C CB  . LEU A 1 94  ? 92.930  105.610 87.004  1.00 73.17  ? 94   LEU A CB  1 
ATOM   413   C CG  . LEU A 1 94  ? 92.100  105.238 85.766  1.00 73.17  ? 94   LEU A CG  1 
ATOM   414   C CD1 . LEU A 1 94  ? 90.624  104.971 86.075  1.00 73.17  ? 94   LEU A CD1 1 
ATOM   415   C CD2 . LEU A 1 94  ? 92.234  106.336 84.722  1.00 73.17  ? 94   LEU A CD2 1 
ATOM   416   N N   . LEU A 1 95  ? 92.532  103.839 89.926  1.00 70.00  ? 95   LEU A N   1 
ATOM   417   C CA  . LEU A 1 95  ? 91.686  102.978 90.746  1.00 70.00  ? 95   LEU A CA  1 
ATOM   418   C C   . LEU A 1 95  ? 90.765  103.743 91.687  1.00 70.00  ? 95   LEU A C   1 
ATOM   419   O O   . LEU A 1 95  ? 89.663  103.274 91.976  1.00 70.00  ? 95   LEU A O   1 
ATOM   420   C CB  . LEU A 1 95  ? 92.573  102.009 91.550  1.00 70.00  ? 95   LEU A CB  1 
ATOM   421   C CG  . LEU A 1 95  ? 92.095  100.692 92.184  1.00 70.00  ? 95   LEU A CG  1 
ATOM   422   C CD1 . LEU A 1 95  ? 93.308  99.807  92.411  1.00 70.00  ? 95   LEU A CD1 1 
ATOM   423   C CD2 . LEU A 1 95  ? 91.352  100.857 93.509  1.00 70.00  ? 95   LEU A CD2 1 
ATOM   424   N N   . GLU A 1 96  ? 91.174  104.921 92.155  1.00 70.70  ? 96   GLU A N   1 
ATOM   425   C CA  . GLU A 1 96  ? 90.570  105.564 93.323  1.00 70.70  ? 96   GLU A CA  1 
ATOM   426   C C   . GLU A 1 96  ? 89.525  106.616 92.969  1.00 70.70  ? 96   GLU A C   1 
ATOM   427   O O   . GLU A 1 96  ? 89.240  107.485 93.801  1.00 70.70  ? 96   GLU A O   1 
ATOM   428   C CB  . GLU A 1 96  ? 91.662  106.165 94.206  1.00 70.70  ? 96   GLU A CB  1 
ATOM   429   C CG  . GLU A 1 96  ? 92.717  105.164 94.697  1.00 70.70  ? 96   GLU A CG  1 
ATOM   430   C CD  . GLU A 1 96  ? 93.894  104.973 93.748  1.00 70.70  ? 96   GLU A CD  1 
ATOM   431   O OE1 . GLU A 1 96  ? 95.009  104.700 94.237  1.00 70.70  ? 96   GLU A OE1 1 
ATOM   432   O OE2 . GLU A 1 96  ? 93.708  105.078 92.519  1.00 70.70  ? 96   GLU A OE2 1 
ATOM   433   N N   . LYS A 1 97  ? 88.947  106.543 91.763  1.00 68.60  ? 97   LYS A N   1 
ATOM   434   C CA  . LYS A 1 97  ? 87.777  107.321 91.330  1.00 68.60  ? 97   LYS A CA  1 
ATOM   435   C C   . LYS A 1 97  ? 88.039  108.831 91.400  1.00 68.60  ? 97   LYS A C   1 
ATOM   436   O O   . LYS A 1 97  ? 87.470  109.557 92.217  1.00 68.60  ? 97   LYS A O   1 
ATOM   437   C CB  . LYS A 1 97  ? 86.531  106.936 92.142  1.00 68.60  ? 97   LYS A CB  1 
ATOM   438   C CG  . LYS A 1 97  ? 86.176  105.457 92.076  1.00 68.60  ? 97   LYS A CG  1 
ATOM   439   C CD  . LYS A 1 97  ? 85.408  104.995 93.310  1.00 68.60  ? 97   LYS A CD  1 
ATOM   440   C CE  . LYS A 1 97  ? 86.098  105.395 94.609  1.00 68.60  ? 97   LYS A CE  1 
ATOM   441   N NZ  . LYS A 1 97  ? 87.468  104.825 94.732  1.00 68.60  ? 97   LYS A NZ  1 
ATOM   442   N N   . ILE A 1 98  ? 88.946  109.274 90.526  1.00 68.68  ? 98   ILE A N   1 
ATOM   443   C CA  . ILE A 1 98  ? 89.374  110.673 90.522  1.00 68.68  ? 98   ILE A CA  1 
ATOM   444   C C   . ILE A 1 98  ? 88.242  111.580 90.046  1.00 68.68  ? 98   ILE A C   1 
ATOM   445   O O   . ILE A 1 98  ? 87.787  112.468 90.774  1.00 68.68  ? 98   ILE A O   1 
ATOM   446   C CB  . ILE A 1 98  ? 90.635  110.864 89.659  1.00 68.68  ? 98   ILE A CB  1 
ATOM   447   C CG1 . ILE A 1 98  ? 91.823  110.055 90.198  1.00 68.68  ? 98   ILE A CG1 1 
ATOM   448   C CG2 . ILE A 1 98  ? 91.006  112.340 89.583  1.00 68.68  ? 98   ILE A CG2 1 
ATOM   449   C CD1 . ILE A 1 98  ? 92.052  108.708 89.511  1.00 68.68  ? 98   ILE A CD1 1 
ATOM   450   N N   . ALA A 1 99  ? 87.771  111.368 88.818  1.00 67.17  ? 99   ALA A N   1 
ATOM   451   C CA  . ALA A 1 99  ? 86.741  112.235 88.256  1.00 67.17  ? 99   ALA A CA  1 
ATOM   452   C C   . ALA A 1 99  ? 85.618  111.430 87.615  1.00 67.17  ? 99   ALA A C   1 
ATOM   453   O O   . ALA A 1 99  ? 85.646  110.194 87.626  1.00 67.17  ? 99   ALA A O   1 
ATOM   454   C CB  . ALA A 1 99  ? 87.353  113.193 87.231  1.00 67.17  ? 99   ALA A CB  1 
ATOM   455   N N   . ASP A 1 100 ? 84.622  112.126 87.060  1.00 72.48  ? 100  ASP A N   1 
ATOM   456   C CA  . ASP A 1 100 ? 83.529  111.446 86.372  1.00 72.48  ? 100  ASP A CA  1 
ATOM   457   C C   . ASP A 1 100 ? 84.003  110.839 85.057  1.00 72.48  ? 100  ASP A C   1 
ATOM   458   O O   . ASP A 1 100 ? 83.522  109.779 84.639  1.00 72.48  ? 100  ASP A O   1 
ATOM   459   C CB  . ASP A 1 100 ? 82.365  112.415 86.149  1.00 72.48  ? 100  ASP A CB  1 
ATOM   460   C CG  . ASP A 1 100 ? 82.786  113.684 85.434  1.00 72.48  ? 100  ASP A CG  1 
ATOM   461   O OD1 . ASP A 1 100 ? 84.002  113.964 85.395  1.00 72.48  ? 100  ASP A OD1 1 
ATOM   462   O OD2 . ASP A 1 100 ? 81.906  114.398 84.911  1.00 72.48  ? 100  ASP A OD2 1 
ATOM   463   N N   . ASP A 1 101 ? 84.943  111.498 84.390  1.00 70.02  ? 101  ASP A N   1 
ATOM   464   C CA  . ASP A 1 101 ? 85.667  110.906 83.277  1.00 70.02  ? 101  ASP A CA  1 
ATOM   465   C C   . ASP A 1 101 ? 87.111  111.386 83.309  1.00 70.02  ? 101  ASP A C   1 
ATOM   466   O O   . ASP A 1 101 ? 87.391  112.583 83.207  1.00 70.02  ? 101  ASP A O   1 
ATOM   467   C CB  . ASP A 1 101 ? 84.983  111.197 81.922  1.00 70.02  ? 101  ASP A CB  1 
ATOM   468   C CG  . ASP A 1 101 ? 84.612  112.657 81.733  1.00 70.02  ? 101  ASP A CG  1 
ATOM   469   O OD1 . ASP A 1 101 ? 84.764  113.460 82.674  1.00 70.02  ? 101  ASP A OD1 1 
ATOM   470   O OD2 . ASP A 1 101 ? 84.147  112.999 80.625  1.00 70.02  ? 101  ASP A OD2 1 
ATOM   471   N N   . THR A 1 102 ? 88.030  110.436 83.480  1.00 67.75  ? 102  THR A N   1 
ATOM   472   C CA  . THR A 1 102 ? 89.437  110.751 83.722  1.00 67.75  ? 102  THR A CA  1 
ATOM   473   C C   . THR A 1 102 ? 90.157  110.914 82.387  1.00 67.75  ? 102  THR A C   1 
ATOM   474   O O   . THR A 1 102 ? 91.001  110.108 81.990  1.00 67.75  ? 102  THR A O   1 
ATOM   475   C CB  . THR A 1 102 ? 90.080  109.668 84.576  1.00 67.75  ? 102  THR A CB  1 
ATOM   476   O OG1 . THR A 1 102 ? 89.638  108.383 84.121  1.00 67.75  ? 102  THR A OG1 1 
ATOM   477   C CG2 . THR A 1 102 ? 89.700  109.845 86.037  1.00 67.75  ? 102  THR A CG2 1 
ATOM   478   N N   . ASP A 1 103 ? 89.808  111.989 81.682  1.00 69.47  ? 103  ASP A N   1 
ATOM   479   C CA  . ASP A 1 103 ? 90.496  112.364 80.456  1.00 69.47  ? 103  ASP A CA  1 
ATOM   480   C C   . ASP A 1 103 ? 91.756  113.175 80.715  1.00 69.47  ? 103  ASP A C   1 
ATOM   481   O O   . ASP A 1 103 ? 92.676  113.146 79.890  1.00 69.47  ? 103  ASP A O   1 
ATOM   482   C CB  . ASP A 1 103 ? 89.555  113.157 79.542  1.00 69.47  ? 103  ASP A CB  1 
ATOM   483   C CG  . ASP A 1 103 ? 89.978  113.111 78.085  1.00 69.47  ? 103  ASP A CG  1 
ATOM   484   O OD1 . ASP A 1 103 ? 90.473  114.138 77.574  1.00 69.47  ? 103  ASP A OD1 1 
ATOM   485   O OD2 . ASP A 1 103 ? 89.818  112.047 77.451  1.00 69.47  ? 103  ASP A OD2 1 
ATOM   486   N N   . ALA A 1 104 ? 91.822  113.889 81.836  1.00 67.44  ? 104  ALA A N   1 
ATOM   487   C CA  . ALA A 1 104 ? 92.997  114.661 82.202  1.00 67.44  ? 104  ALA A CA  1 
ATOM   488   C C   . ALA A 1 104 ? 93.873  113.947 83.219  1.00 67.44  ? 104  ALA A C   1 
ATOM   489   O O   . ALA A 1 104 ? 95.003  114.386 83.459  1.00 67.44  ? 104  ALA A O   1 
ATOM   490   C CB  . ALA A 1 104 ? 92.583  116.032 82.748  1.00 67.44  ? 104  ALA A CB  1 
ATOM   491   N N   . ALA A 1 105 ? 93.384  112.861 83.822  1.00 63.05  ? 105  ALA A N   1 
ATOM   492   C CA  . ALA A 1 105 ? 94.227  112.079 84.717  1.00 63.05  ? 105  ALA A CA  1 
ATOM   493   C C   . ALA A 1 105 ? 95.296  111.320 83.949  1.00 63.05  ? 105  ALA A C   1 
ATOM   494   O O   . ALA A 1 105 ? 96.381  111.073 84.483  1.00 63.05  ? 105  ALA A O   1 
ATOM   495   C CB  . ALA A 1 105 ? 93.380  111.113 85.542  1.00 63.05  ? 105  ALA A CB  1 
ATOM   496   N N   . LYS A 1 106 ? 95.015  110.941 82.702  1.00 64.48  ? 106  LYS A N   1 
ATOM   497   C CA  . LYS A 1 106 ? 96.057  110.322 81.893  1.00 64.48  ? 106  LYS A CA  1 
ATOM   498   C C   . LYS A 1 106 ? 97.015  111.363 81.331  1.00 64.48  ? 106  LYS A C   1 
ATOM   499   O O   . LYS A 1 106 ? 98.153  111.027 80.991  1.00 64.48  ? 106  LYS A O   1 
ATOM   500   C CB  . LYS A 1 106 ? 95.443  109.490 80.768  1.00 64.48  ? 106  LYS A CB  1 
ATOM   501   C CG  . LYS A 1 106 ? 94.662  110.278 79.724  1.00 64.48  ? 106  LYS A CG  1 
ATOM   502   C CD  . LYS A 1 106 ? 94.345  109.407 78.514  1.00 64.48  ? 106  LYS A CD  1 
ATOM   503   C CE  . LYS A 1 106 ? 95.598  108.757 77.930  1.00 64.48  ? 106  LYS A CE  1 
ATOM   504   N NZ  . LYS A 1 106 ? 96.687  109.745 77.669  1.00 64.48  ? 106  LYS A NZ  1 
ATOM   505   N N   . GLU A 1 107 ? 96.578  112.625 81.232  1.00 69.84  ? 107  GLU A N   1 
ATOM   506   C CA  . GLU A 1 107 ? 97.473  113.711 80.843  1.00 69.84  ? 107  GLU A CA  1 
ATOM   507   C C   . GLU A 1 107 ? 98.519  113.976 81.921  1.00 69.84  ? 107  GLU A C   1 
ATOM   508   O O   . GLU A 1 107 ? 99.635  114.408 81.601  1.00 69.84  ? 107  GLU A O   1 
ATOM   509   C CB  . GLU A 1 107 ? 96.652  114.976 80.538  1.00 69.84  ? 107  GLU A CB  1 
ATOM   510   C CG  . GLU A 1 107 ? 97.450  116.248 80.234  1.00 69.84  ? 107  GLU A CG  1 
ATOM   511   C CD  . GLU A 1 107 ? 96.704  117.510 80.587  1.00 69.84  ? 107  GLU A CD  1 
ATOM   512   O OE1 . GLU A 1 107 ? 95.908  117.996 79.758  1.00 69.84  ? 107  GLU A OE1 1 
ATOM   513   O OE2 . GLU A 1 107 ? 96.895  118.013 81.716  1.00 69.84  ? 107  GLU A OE2 1 
ATOM   514   N N   . PHE A 1 108 ? 98.186  113.685 83.185  1.00 69.31  ? 108  PHE A N   1 
ATOM   515   C CA  . PHE A 1 108 ? 99.169  113.713 84.265  1.00 69.31  ? 108  PHE A CA  1 
ATOM   516   C C   . PHE A 1 108 ? 100.298 112.723 83.991  1.00 69.31  ? 108  PHE A C   1 
ATOM   517   O O   . PHE A 1 108 ? 101.471 113.027 84.227  1.00 69.31  ? 108  PHE A O   1 
ATOM   518   C CB  . PHE A 1 108 ? 98.477  113.396 85.596  1.00 69.31  ? 108  PHE A CB  1 
ATOM   519   C CG  . PHE A 1 108 ? 99.378  113.467 86.813  1.00 69.31  ? 108  PHE A CG  1 
ATOM   520   C CD1 . PHE A 1 108 ? 100.427 114.379 86.898  1.00 69.31  ? 108  PHE A CD1 1 
ATOM   521   C CD2 . PHE A 1 108 ? 99.175  112.597 87.875  1.00 69.31  ? 108  PHE A CD2 1 
ATOM   522   C CE1 . PHE A 1 108 ? 101.241 114.423 88.019  1.00 69.31  ? 108  PHE A CE1 1 
ATOM   523   C CE2 . PHE A 1 108 ? 99.989  112.635 88.994  1.00 69.31  ? 108  PHE A CE2 1 
ATOM   524   C CZ  . PHE A 1 108 ? 101.021 113.548 89.067  1.00 69.31  ? 108  PHE A CZ  1 
ATOM   525   N N   . PHE A 1 109 ? 99.970  111.551 83.450  1.00 70.41  ? 109  PHE A N   1 
ATOM   526   C CA  . PHE A 1 109 ? 100.976 110.541 83.151  1.00 70.41  ? 109  PHE A CA  1 
ATOM   527   C C   . PHE A 1 109 ? 101.280 110.408 81.665  1.00 70.41  ? 109  PHE A C   1 
ATOM   528   O O   . PHE A 1 109 ? 102.042 109.514 81.282  1.00 70.41  ? 109  PHE A O   1 
ATOM   529   C CB  . PHE A 1 109 ? 100.561 109.176 83.696  1.00 70.41  ? 109  PHE A CB  1 
ATOM   530   C CG  . PHE A 1 109 ? 100.125 109.187 85.130  1.00 70.41  ? 109  PHE A CG  1 
ATOM   531   C CD1 . PHE A 1 109 ? 101.054 109.021 86.145  1.00 70.41  ? 109  PHE A CD1 1 
ATOM   532   C CD2 . PHE A 1 109 ? 98.784  109.266 85.461  1.00 70.41  ? 109  PHE A CD2 1 
ATOM   533   C CE1 . PHE A 1 109 ? 100.660 109.011 87.469  1.00 70.41  ? 109  PHE A CE1 1 
ATOM   534   C CE2 . PHE A 1 109 ? 98.378  109.248 86.782  1.00 70.41  ? 109  PHE A CE2 1 
ATOM   535   C CZ  . PHE A 1 109 ? 99.318  109.113 87.787  1.00 70.41  ? 109  PHE A CZ  1 
ATOM   536   N N   . ALA A 1 110 ? 100.710 111.264 80.815  1.00 68.11  ? 110  ALA A N   1 
ATOM   537   C CA  . ALA A 1 110 ? 101.111 111.273 79.414  1.00 68.11  ? 110  ALA A CA  1 
ATOM   538   C C   . ALA A 1 110 ? 102.489 111.882 79.222  1.00 68.11  ? 110  ALA A C   1 
ATOM   539   O O   . ALA A 1 110 ? 103.138 111.620 78.203  1.00 68.11  ? 110  ALA A O   1 
ATOM   540   C CB  . ALA A 1 110 ? 100.095 112.038 78.563  1.00 68.11  ? 110  ALA A CB  1 
ATOM   541   N N   . CYS A 1 111 ? 102.949 112.679 80.182  1.00 70.12  ? 111  CYS A N   1 
ATOM   542   C CA  . CYS A 1 111 ? 104.260 113.300 80.126  1.00 70.12  ? 111  CYS A CA  1 
ATOM   543   C C   . CYS A 1 111 ? 105.184 112.871 81.251  1.00 70.12  ? 111  CYS A C   1 
ATOM   544   O O   . CYS A 1 111 ? 106.381 112.732 81.012  1.00 70.12  ? 111  CYS A O   1 
ATOM   545   C CB  . CYS A 1 111 ? 104.125 114.827 80.158  1.00 70.12  ? 111  CYS A CB  1 
ATOM   546   S SG  . CYS A 1 111 ? 102.982 115.433 81.418  1.00 70.12  ? 111  CYS A SG  1 
ATOM   547   N N   . LEU A 1 112 ? 104.650 112.624 82.453  1.00 66.84  ? 112  LEU A N   1 
ATOM   548   C CA  . LEU A 1 112 ? 105.474 112.404 83.640  1.00 66.84  ? 112  LEU A CA  1 
ATOM   549   C C   . LEU A 1 112 ? 106.281 111.116 83.575  1.00 66.84  ? 112  LEU A C   1 
ATOM   550   O O   . LEU A 1 112 ? 107.439 111.099 84.004  1.00 66.84  ? 112  LEU A O   1 
ATOM   551   C CB  . LEU A 1 112 ? 104.593 112.417 84.894  1.00 66.84  ? 112  LEU A CB  1 
ATOM   552   C CG  . LEU A 1 112 ? 105.171 112.154 86.288  1.00 66.84  ? 112  LEU A CG  1 
ATOM   553   C CD1 . LEU A 1 112 ? 104.555 113.082 87.313  1.00 66.84  ? 112  LEU A CD1 1 
ATOM   554   C CD2 . LEU A 1 112 ? 104.865 110.720 86.699  1.00 66.84  ? 112  LEU A CD2 1 
ATOM   555   N N   . ASP A 1 113 ? 105.701 110.038 83.050  1.00 70.60  ? 113  ASP A N   1 
ATOM   556   C CA  . ASP A 1 113 ? 106.458 108.799 82.924  1.00 70.60  ? 113  ASP A CA  1 
ATOM   557   C C   . ASP A 1 113 ? 107.493 108.890 81.813  1.00 70.60  ? 113  ASP A C   1 
ATOM   558   O O   . ASP A 1 113 ? 108.462 108.124 81.807  1.00 70.60  ? 113  ASP A O   1 
ATOM   559   C CB  . ASP A 1 113 ? 105.502 107.634 82.707  1.00 70.60  ? 113  ASP A CB  1 
ATOM   560   C CG  . ASP A 1 113 ? 104.503 107.502 83.834  1.00 70.60  ? 113  ASP A CG  1 
ATOM   561   O OD1 . ASP A 1 113 ? 104.518 106.474 84.544  1.00 70.60  ? 113  ASP A OD1 1 
ATOM   562   O OD2 . ASP A 1 113 ? 103.726 108.455 84.035  1.00 70.60  ? 113  ASP A OD2 1 
ATOM   563   N N   . MET A 1 114 ? 107.309 109.811 80.868  1.00 73.32  ? 114  MET A N   1 
ATOM   564   C CA  . MET A 1 114 ? 108.381 110.129 79.940  1.00 73.32  ? 114  MET A CA  1 
ATOM   565   C C   . MET A 1 114 ? 109.509 110.899 80.614  1.00 73.32  ? 114  MET A C   1 
ATOM   566   O O   . MET A 1 114 ? 110.666 110.749 80.208  1.00 73.32  ? 114  MET A O   1 
ATOM   567   C CB  . MET A 1 114 ? 107.845 110.925 78.746  1.00 73.32  ? 114  MET A CB  1 
ATOM   568   C CG  . MET A 1 114 ? 106.514 110.443 78.156  1.00 73.32  ? 114  MET A CG  1 
ATOM   569   S SD  . MET A 1 114 ? 106.518 108.755 77.502  1.00 73.32  ? 114  MET A SD  1 
ATOM   570   C CE  . MET A 1 114 ? 105.621 107.838 78.756  1.00 73.32  ? 114  MET A CE  1 
ATOM   571   N N   . GLN A 1 115 ? 109.204 111.707 81.638  1.00 67.20  ? 115  GLN A N   1 
ATOM   572   C CA  . GLN A 1 115 ? 110.262 112.358 82.405  1.00 67.20  ? 115  GLN A CA  1 
ATOM   573   C C   . GLN A 1 115 ? 111.068 111.367 83.226  1.00 67.20  ? 115  GLN A C   1 
ATOM   574   O O   . GLN A 1 115 ? 112.216 111.662 83.573  1.00 67.20  ? 115  GLN A O   1 
ATOM   575   C CB  . GLN A 1 115 ? 109.700 113.430 83.340  1.00 67.20  ? 115  GLN A CB  1 
ATOM   576   C CG  . GLN A 1 115 ? 108.576 114.248 82.768  1.00 67.20  ? 115  GLN A CG  1 
ATOM   577   C CD  . GLN A 1 115 ? 109.065 115.380 81.900  1.00 67.20  ? 115  GLN A CD  1 
ATOM   578   O OE1 . GLN A 1 115 ? 109.649 116.338 82.394  1.00 67.20  ? 115  GLN A OE1 1 
ATOM   579   N NE2 . GLN A 1 115 ? 108.829 115.277 80.598  1.00 67.20  ? 115  GLN A NE2 1 
ATOM   580   N N   . LEU A 1 116 ? 110.483 110.220 83.573  1.00 62.85  ? 116  LEU A N   1 
ATOM   581   C CA  . LEU A 1 116 ? 111.267 109.139 84.155  1.00 62.85  ? 116  LEU A CA  1 
ATOM   582   C C   . LEU A 1 116 ? 112.292 108.631 83.154  1.00 62.85  ? 116  LEU A C   1 
ATOM   583   O O   . LEU A 1 116 ? 113.468 108.457 83.486  1.00 62.85  ? 116  LEU A O   1 
ATOM   584   C CB  . LEU A 1 116 ? 110.355 107.997 84.617  1.00 62.85  ? 116  LEU A CB  1 
ATOM   585   C CG  . LEU A 1 116 ? 109.743 107.993 86.025  1.00 62.85  ? 116  LEU A CG  1 
ATOM   586   C CD1 . LEU A 1 116 ? 110.840 107.955 87.082  1.00 62.85  ? 116  LEU A CD1 1 
ATOM   587   C CD2 . LEU A 1 116 ? 108.787 109.144 86.277  1.00 62.85  ? 116  LEU A CD2 1 
ATOM   588   N N   . ASN A 1 117 ? 111.862 108.416 81.908  1.00 62.28  ? 117  ASN A N   1 
ATOM   589   C CA  . ASN A 1 117 ? 112.766 107.909 80.883  1.00 62.28  ? 117  ASN A CA  1 
ATOM   590   C C   . ASN A 1 117 ? 113.785 108.959 80.475  1.00 62.28  ? 117  ASN A C   1 
ATOM   591   O O   . ASN A 1 117 ? 114.942 108.628 80.196  1.00 62.28  ? 117  ASN A O   1 
ATOM   592   C CB  . ASN A 1 117 ? 111.971 107.462 79.660  1.00 62.28  ? 117  ASN A CB  1 
ATOM   593   C CG  . ASN A 1 117 ? 111.033 106.330 79.963  1.00 62.28  ? 117  ASN A CG  1 
ATOM   594   O OD1 . ASN A 1 117 ? 110.570 106.183 81.092  1.00 62.28  ? 117  ASN A OD1 1 
ATOM   595   N ND2 . ASN A 1 117 ? 110.742 105.518 78.956  1.00 62.28  ? 117  ASN A ND2 1 
ATOM   596   N N   . LYS A 1 118 ? 113.367 110.232 80.452  1.00 60.52  ? 118  LYS A N   1 
ATOM   597   C CA  . LYS A 1 118 ? 114.209 111.332 79.987  1.00 60.52  ? 118  LYS A CA  1 
ATOM   598   C C   . LYS A 1 118 ? 115.457 111.492 80.840  1.00 60.52  ? 118  LYS A C   1 
ATOM   599   O O   . LYS A 1 118 ? 116.537 111.791 80.317  1.00 60.52  ? 118  LYS A O   1 
ATOM   600   C CB  . LYS A 1 118 ? 113.400 112.630 79.986  1.00 60.52  ? 118  LYS A CB  1 
ATOM   601   C CG  . LYS A 1 118 ? 114.083 113.820 79.340  1.00 60.52  ? 118  LYS A CG  1 
ATOM   602   C CD  . LYS A 1 118 ? 113.416 115.119 79.764  1.00 60.52  ? 118  LYS A CD  1 
ATOM   603   C CE  . LYS A 1 118 ? 113.676 115.420 81.230  1.00 60.52  ? 118  LYS A CE  1 
ATOM   604   N NZ  . LYS A 1 118 ? 113.348 116.827 81.589  1.00 60.52  ? 118  LYS A NZ  1 
ATOM   605   N N   . VAL A 1 119 ? 115.333 111.278 82.143  1.00 55.85  ? 119  VAL A N   1 
ATOM   606   C CA  . VAL A 1 119 ? 116.511 111.182 82.984  1.00 55.85  ? 119  VAL A CA  1 
ATOM   607   C C   . VAL A 1 119 ? 117.184 109.823 82.830  1.00 55.85  ? 119  VAL A C   1 
ATOM   608   O O   . VAL A 1 119 ? 118.414 109.739 82.856  1.00 55.85  ? 119  VAL A O   1 
ATOM   609   C CB  . VAL A 1 119 ? 116.128 111.459 84.446  1.00 55.85  ? 119  VAL A CB  1 
ATOM   610   C CG1 . VAL A 1 119 ? 117.359 111.678 85.293  1.00 55.85  ? 119  VAL A CG1 1 
ATOM   611   C CG2 . VAL A 1 119 ? 115.221 112.670 84.528  1.00 55.85  ? 119  VAL A CG2 1 
ATOM   612   N N   . ASN A 1 120 ? 116.410 108.760 82.604  1.00 58.86  ? 120  ASN A N   1 
ATOM   613   C CA  . ASN A 1 120 ? 116.985 107.418 82.636  1.00 58.86  ? 120  ASN A CA  1 
ATOM   614   C C   . ASN A 1 120 ? 117.664 107.069 81.322  1.00 58.86  ? 120  ASN A C   1 
ATOM   615   O O   . ASN A 1 120 ? 118.638 106.309 81.305  1.00 58.86  ? 120  ASN A O   1 
ATOM   616   C CB  . ASN A 1 120 ? 115.914 106.388 82.970  1.00 58.86  ? 120  ASN A CB  1 
ATOM   617   C CG  . ASN A 1 120 ? 115.587 106.352 84.444  1.00 58.86  ? 120  ASN A CG  1 
ATOM   618   O OD1 . ASN A 1 120 ? 114.802 105.522 84.894  1.00 58.86  ? 120  ASN A OD1 1 
ATOM   619   N ND2 . ASN A 1 120 ? 116.198 107.245 85.210  1.00 58.86  ? 120  ASN A ND2 1 
ATOM   620   N N   . GLN A 1 121 ? 117.158 107.597 80.205  1.00 57.84  ? 121  GLN A N   1 
ATOM   621   C CA  . GLN A 1 121 ? 117.878 107.424 78.949  1.00 57.84  ? 121  GLN A CA  1 
ATOM   622   C C   . GLN A 1 121 ? 119.179 108.217 78.946  1.00 57.84  ? 121  GLN A C   1 
ATOM   623   O O   . GLN A 1 121 ? 120.158 107.791 78.326  1.00 57.84  ? 121  GLN A O   1 
ATOM   624   C CB  . GLN A 1 121 ? 117.008 107.827 77.755  1.00 57.84  ? 121  GLN A CB  1 
ATOM   625   C CG  . GLN A 1 121 ? 115.776 106.954 77.535  1.00 57.84  ? 121  GLN A CG  1 
ATOM   626   C CD  . GLN A 1 121 ? 114.590 107.734 76.986  1.00 57.84  ? 121  GLN A CD  1 
ATOM   627   O OE1 . GLN A 1 121 ? 114.354 108.880 77.365  1.00 57.84  ? 121  GLN A OE1 1 
ATOM   628   N NE2 . GLN A 1 121 ? 113.832 107.106 76.094  1.00 57.84  ? 121  GLN A NE2 1 
ATOM   629   N N   . PHE A 1 122 ? 119.217 109.352 79.647  1.00 55.56  ? 122  PHE A N   1 
ATOM   630   C CA  . PHE A 1 122 ? 120.410 110.189 79.612  1.00 55.56  ? 122  PHE A CA  1 
ATOM   631   C C   . PHE A 1 122 ? 121.443 109.730 80.634  1.00 55.56  ? 122  PHE A C   1 
ATOM   632   O O   . PHE A 1 122 ? 122.621 109.582 80.295  1.00 55.56  ? 122  PHE A O   1 
ATOM   633   C CB  . PHE A 1 122 ? 120.043 111.656 79.835  1.00 55.56  ? 122  PHE A CB  1 
ATOM   634   C CG  . PHE A 1 122 ? 121.232 112.578 79.874  1.00 55.56  ? 122  PHE A CG  1 
ATOM   635   C CD1 . PHE A 1 122 ? 121.392 113.481 80.907  1.00 55.56  ? 122  PHE A CD1 1 
ATOM   636   C CD2 . PHE A 1 122 ? 122.195 112.534 78.876  1.00 55.56  ? 122  PHE A CD2 1 
ATOM   637   C CE1 . PHE A 1 122 ? 122.482 114.326 80.948  1.00 55.56  ? 122  PHE A CE1 1 
ATOM   638   C CE2 . PHE A 1 122 ? 123.291 113.373 78.912  1.00 55.56  ? 122  PHE A CE2 1 
ATOM   639   C CZ  . PHE A 1 122 ? 123.434 114.270 79.949  1.00 55.56  ? 122  PHE A CZ  1 
ATOM   640   N N   . TYR A 1 123 ? 121.017 109.514 81.890  1.00 55.94  ? 123  TYR A N   1 
ATOM   641   C CA  . TYR A 1 123 ? 121.947 109.164 82.967  1.00 55.94  ? 123  TYR A CA  1 
ATOM   642   C C   . TYR A 1 123 ? 122.634 107.836 82.696  1.00 55.94  ? 123  TYR A C   1 
ATOM   643   O O   . TYR A 1 123 ? 123.810 107.668 83.025  1.00 55.94  ? 123  TYR A O   1 
ATOM   644   C CB  . TYR A 1 123 ? 121.212 109.117 84.315  1.00 55.94  ? 123  TYR A CB  1 
ATOM   645   C CG  . TYR A 1 123 ? 122.070 108.945 85.572  1.00 55.94  ? 123  TYR A CG  1 
ATOM   646   C CD1 . TYR A 1 123 ? 122.513 107.685 85.988  1.00 55.94  ? 123  TYR A CD1 1 
ATOM   647   C CD2 . TYR A 1 123 ? 122.386 110.036 86.377  1.00 55.94  ? 123  TYR A CD2 1 
ATOM   648   C CE1 . TYR A 1 123 ? 123.282 107.527 87.129  1.00 55.94  ? 123  TYR A CE1 1 
ATOM   649   C CE2 . TYR A 1 123 ? 123.143 109.877 87.534  1.00 55.94  ? 123  TYR A CE2 1 
ATOM   650   C CZ  . TYR A 1 123 ? 123.582 108.619 87.901  1.00 55.94  ? 123  TYR A CZ  1 
ATOM   651   O OH  . TYR A 1 123 ? 124.337 108.443 89.034  1.00 55.94  ? 123  TYR A OH  1 
ATOM   652   N N   . LYS A 1 124 ? 121.910 106.877 82.113  1.00 55.68  ? 124  LYS A N   1 
ATOM   653   C CA  . LYS A 1 124 ? 122.541 105.629 81.703  1.00 55.68  ? 124  LYS A CA  1 
ATOM   654   C C   . LYS A 1 124 ? 123.545 105.871 80.587  1.00 55.68  ? 124  LYS A C   1 
ATOM   655   O O   . LYS A 1 124 ? 124.630 105.282 80.585  1.00 55.68  ? 124  LYS A O   1 
ATOM   656   C CB  . LYS A 1 124 ? 121.485 104.621 81.259  1.00 55.68  ? 124  LYS A CB  1 
ATOM   657   C CG  . LYS A 1 124 ? 122.039 103.242 80.973  1.00 55.68  ? 124  LYS A CG  1 
ATOM   658   C CD  . LYS A 1 124 ? 122.654 102.658 82.225  1.00 55.68  ? 124  LYS A CD  1 
ATOM   659   C CE  . LYS A 1 124 ? 123.399 101.368 81.955  1.00 55.68  ? 124  LYS A CE  1 
ATOM   660   N NZ  . LYS A 1 124 ? 124.606 101.592 81.122  1.00 55.68  ? 124  LYS A NZ  1 
ATOM   661   N N   . THR A 1 125 ? 123.215 106.762 79.652  1.00 56.01  ? 125  THR A N   1 
ATOM   662   C CA  . THR A 1 125 ? 124.133 107.061 78.561  1.00 56.01  ? 125  THR A CA  1 
ATOM   663   C C   . THR A 1 125 ? 125.243 107.999 79.017  1.00 56.01  ? 125  THR A C   1 
ATOM   664   O O   . THR A 1 125 ? 126.391 107.858 78.579  1.00 56.01  ? 125  THR A O   1 
ATOM   665   C CB  . THR A 1 125 ? 123.355 107.655 77.387  1.00 56.01  ? 125  THR A CB  1 
ATOM   666   O OG1 . THR A 1 125 ? 122.275 106.774 77.051  1.00 56.01  ? 125  THR A OG1 1 
ATOM   667   C CG2 . THR A 1 125 ? 124.242 107.815 76.158  1.00 56.01  ? 125  THR A CG2 1 
ATOM   668   N N   . LYS A 1 126 ? 124.931 108.939 79.915  1.00 57.05  ? 126  LYS A N   1 
ATOM   669   C CA  . LYS A 1 126 ? 125.977 109.794 80.469  1.00 57.05  ? 126  LYS A CA  1 
ATOM   670   C C   . LYS A 1 126 ? 126.911 109.008 81.374  1.00 57.05  ? 126  LYS A C   1 
ATOM   671   O O   . LYS A 1 126 ? 128.104 109.320 81.443  1.00 57.05  ? 126  LYS A O   1 
ATOM   672   C CB  . LYS A 1 126 ? 125.375 110.972 81.236  1.00 57.05  ? 126  LYS A CB  1 
ATOM   673   C CG  . LYS A 1 126 ? 126.323 112.150 81.419  1.00 57.05  ? 126  LYS A CG  1 
ATOM   674   C CD  . LYS A 1 126 ? 127.017 112.524 80.118  1.00 57.05  ? 126  LYS A CD  1 
ATOM   675   C CE  . LYS A 1 126 ? 128.291 113.307 80.373  1.00 57.05  ? 126  LYS A CE  1 
ATOM   676   N NZ  . LYS A 1 126 ? 128.865 113.851 79.112  1.00 57.05  ? 126  LYS A NZ  1 
ATOM   677   N N   . GLU A 1 127 ? 126.397 107.996 82.074  1.00 56.24  ? 127  GLU A N   1 
ATOM   678   C CA  . GLU A 1 127 ? 127.297 107.047 82.714  1.00 56.24  ? 127  GLU A CA  1 
ATOM   679   C C   . GLU A 1 127 ? 128.027 106.206 81.680  1.00 56.24  ? 127  GLU A C   1 
ATOM   680   O O   . GLU A 1 127 ? 129.207 105.909 81.858  1.00 56.24  ? 127  GLU A O   1 
ATOM   681   C CB  . GLU A 1 127 ? 126.550 106.147 83.696  1.00 56.24  ? 127  GLU A CB  1 
ATOM   682   C CG  . GLU A 1 127 ? 127.440 105.549 84.778  1.00 56.24  ? 127  GLU A CG  1 
ATOM   683   C CD  . GLU A 1 127 ? 126.700 104.563 85.664  1.00 56.24  ? 127  GLU A CD  1 
ATOM   684   O OE1 . GLU A 1 127 ? 127.123 103.393 85.725  1.00 56.24  ? 127  GLU A OE1 1 
ATOM   685   O OE2 . GLU A 1 127 ? 125.715 104.958 86.319  1.00 56.24  ? 127  GLU A OE2 1 
ATOM   686   N N   . LYS A 1 128 ? 127.345 105.815 80.594  1.00 58.32  ? 128  LYS A N   1 
ATOM   687   C CA  . LYS A 1 128 ? 128.005 105.051 79.533  1.00 58.32  ? 128  LYS A CA  1 
ATOM   688   C C   . LYS A 1 128 ? 129.076 105.871 78.832  1.00 58.32  ? 128  LYS A C   1 
ATOM   689   O O   . LYS A 1 128 ? 130.118 105.327 78.450  1.00 58.32  ? 128  LYS A O   1 
ATOM   690   C CB  . LYS A 1 128 ? 126.989 104.558 78.502  1.00 58.32  ? 128  LYS A CB  1 
ATOM   691   C CG  . LYS A 1 128 ? 126.444 103.165 78.757  1.00 58.32  ? 128  LYS A CG  1 
ATOM   692   C CD  . LYS A 1 128 ? 125.103 102.975 78.064  1.00 58.32  ? 128  LYS A CD  1 
ATOM   693   C CE  . LYS A 1 128 ? 125.257 102.852 76.560  1.00 58.32  ? 128  LYS A CE  1 
ATOM   694   N NZ  . LYS A 1 128 ? 126.003 101.623 76.179  1.00 58.32  ? 128  LYS A NZ  1 
ATOM   695   N N   . GLU A 1 129 ? 128.833 107.171 78.645  1.00 55.53  ? 129  GLU A N   1 
ATOM   696   C CA  . GLU A 1 129 ? 129.892 108.053 78.174  1.00 55.53  ? 129  GLU A CA  1 
ATOM   697   C C   . GLU A 1 129 ? 130.991 108.169 79.217  1.00 55.53  ? 129  GLU A C   1 
ATOM   698   O O   . GLU A 1 129 ? 132.175 108.170 78.869  1.00 55.53  ? 129  GLU A O   1 
ATOM   699   C CB  . GLU A 1 129 ? 129.318 109.431 77.826  1.00 55.53  ? 129  GLU A CB  1 
ATOM   700   C CG  . GLU A 1 129 ? 130.085 110.221 76.752  1.00 55.53  ? 129  GLU A CG  1 
ATOM   701   C CD  . GLU A 1 129 ? 131.431 110.751 77.215  1.00 55.53  ? 129  GLU A CD  1 
ATOM   702   O OE1 . GLU A 1 129 ? 132.360 110.829 76.383  1.00 55.53  ? 129  GLU A OE1 1 
ATOM   703   O OE2 . GLU A 1 129 ? 131.558 111.106 78.403  1.00 55.53  ? 129  GLU A OE2 1 
ATOM   704   N N   . PHE A 1 130 ? 130.623 108.252 80.493  1.00 55.67  ? 130  PHE A N   1 
ATOM   705   C CA  . PHE A 1 130 ? 131.606 108.260 81.566  1.00 55.67  ? 130  PHE A CA  1 
ATOM   706   C C   . PHE A 1 130 ? 132.098 106.869 81.932  1.00 55.67  ? 130  PHE A C   1 
ATOM   707   O O   . PHE A 1 130 ? 132.962 106.755 82.801  1.00 55.67  ? 130  PHE A O   1 
ATOM   708   C CB  . PHE A 1 130 ? 131.032 108.950 82.801  1.00 55.67  ? 130  PHE A CB  1 
ATOM   709   C CG  . PHE A 1 130 ? 131.185 110.441 82.783  1.00 55.67  ? 130  PHE A CG  1 
ATOM   710   C CD1 . PHE A 1 130 ? 132.313 111.025 82.235  1.00 55.67  ? 130  PHE A CD1 1 
ATOM   711   C CD2 . PHE A 1 130 ? 130.191 111.258 83.294  1.00 55.67  ? 130  PHE A CD2 1 
ATOM   712   C CE1 . PHE A 1 130 ? 132.456 112.395 82.215  1.00 55.67  ? 130  PHE A CE1 1 
ATOM   713   C CE2 . PHE A 1 130 ? 130.329 112.627 83.279  1.00 55.67  ? 130  PHE A CE2 1 
ATOM   714   C CZ  . PHE A 1 130 ? 131.462 113.196 82.736  1.00 55.67  ? 130  PHE A CZ  1 
ATOM   715   N N   . LEU A 1 131 ? 131.529 105.809 81.348  1.00 57.49  ? 131  LEU A N   1 
ATOM   716   C CA  . LEU A 1 131 ? 132.263 104.551 81.284  1.00 57.49  ? 131  LEU A CA  1 
ATOM   717   C C   . LEU A 1 131 ? 133.263 104.577 80.144  1.00 57.49  ? 131  LEU A C   1 
ATOM   718   O O   . LEU A 1 131 ? 134.392 104.115 80.314  1.00 57.49  ? 131  LEU A O   1 
ATOM   719   C CB  . LEU A 1 131 ? 131.333 103.340 81.123  1.00 57.49  ? 131  LEU A CB  1 
ATOM   720   C CG  . LEU A 1 131 ? 130.306 102.911 82.180  1.00 57.49  ? 131  LEU A CG  1 
ATOM   721   C CD1 . LEU A 1 131 ? 129.902 101.450 81.995  1.00 57.49  ? 131  LEU A CD1 1 
ATOM   722   C CD2 . LEU A 1 131 ? 130.805 103.177 83.598  1.00 57.49  ? 131  LEU A CD2 1 
ATOM   723   N N   . GLU A 1 132 ? 132.871 105.125 78.991  1.00 59.07  ? 132  GLU A N   1 
ATOM   724   C CA  . GLU A 1 132 ? 133.821 105.354 77.908  1.00 59.07  ? 132  GLU A CA  1 
ATOM   725   C C   . GLU A 1 132 ? 134.859 106.386 78.322  1.00 59.07  ? 132  GLU A C   1 
ATOM   726   O O   . GLU A 1 132 ? 136.028 106.302 77.937  1.00 59.07  ? 132  GLU A O   1 
ATOM   727   C CB  . GLU A 1 132 ? 133.081 105.808 76.651  1.00 59.07  ? 132  GLU A CB  1 
ATOM   728   C CG  . GLU A 1 132 ? 133.905 105.743 75.378  1.00 59.07  ? 132  GLU A CG  1 
ATOM   729   C CD  . GLU A 1 132 ? 134.181 104.321 74.933  1.00 59.07  ? 132  GLU A CD  1 
ATOM   730   O OE1 . GLU A 1 132 ? 133.284 103.704 74.321  1.00 59.07  ? 132  GLU A OE1 1 
ATOM   731   O OE2 . GLU A 1 132 ? 135.292 103.814 75.193  1.00 59.07  ? 132  GLU A OE2 1 
ATOM   732   N N   . ARG A 1 133 ? 134.445 107.365 79.121  1.00 55.12  ? 133  ARG A N   1 
ATOM   733   C CA  . ARG A 1 133 ? 135.362 108.195 79.882  1.00 55.12  ? 133  ARG A CA  1 
ATOM   734   C C   . ARG A 1 133 ? 135.567 107.664 81.290  1.00 55.12  ? 133  ARG A C   1 
ATOM   735   O O   . ARG A 1 133 ? 135.581 108.451 82.239  1.00 55.12  ? 133  ARG A O   1 
ATOM   736   C CB  . ARG A 1 133 ? 134.883 109.647 79.931  1.00 55.12  ? 133  ARG A CB  1 
ATOM   737   C CG  . ARG A 1 133 ? 135.149 110.423 78.654  1.00 55.12  ? 133  ARG A CG  1 
ATOM   738   C CD  . ARG A 1 133 ? 135.651 111.831 78.959  1.00 55.12  ? 133  ARG A CD  1 
ATOM   739   N NE  . ARG A 1 133 ? 134.603 112.700 79.482  1.00 55.12  ? 133  ARG A NE  1 
ATOM   740   C CZ  . ARG A 1 133 ? 133.761 113.389 78.723  1.00 55.12  ? 133  ARG A CZ  1 
ATOM   741   N NH1 . ARG A 1 133 ? 133.844 113.318 77.402  1.00 55.12  ? 133  ARG A NH1 1 
ATOM   742   N NH2 . ARG A 1 133 ? 132.836 114.152 79.284  1.00 55.12  ? 133  ARG A NH2 1 
ATOM   743   N N   . GLY A 1 134 ? 135.596 106.343 81.453  1.00 56.05  ? 134  GLY A N   1 
ATOM   744   C CA  . GLY A 1 134 ? 135.984 105.727 82.705  1.00 56.05  ? 134  GLY A CA  1 
ATOM   745   C C   . GLY A 1 134 ? 136.882 104.523 82.533  1.00 56.05  ? 134  GLY A C   1 
ATOM   746   O O   . GLY A 1 134 ? 137.389 103.991 83.522  1.00 56.05  ? 134  GLY A O   1 
ATOM   747   N N   . GLU A 1 135 ? 137.083 104.075 81.291  1.00 61.65  ? 135  GLU A N   1 
ATOM   748   C CA  . GLU A 1 135 ? 138.013 102.976 81.038  1.00 61.65  ? 135  GLU A CA  1 
ATOM   749   C C   . GLU A 1 135 ? 139.128 103.312 80.061  1.00 61.65  ? 135  GLU A C   1 
ATOM   750   O O   . GLU A 1 135 ? 140.185 102.678 80.139  1.00 61.65  ? 135  GLU A O   1 
ATOM   751   C CB  . GLU A 1 135 ? 137.276 101.722 80.541  1.00 61.65  ? 135  GLU A CB  1 
ATOM   752   C CG  . GLU A 1 135 ? 136.435 101.887 79.286  1.00 61.65  ? 135  GLU A CG  1 
ATOM   753   C CD  . GLU A 1 135 ? 137.156 101.486 78.020  1.00 61.65  ? 135  GLU A CD  1 
ATOM   754   O OE1 . GLU A 1 135 ? 138.076 100.646 78.095  1.00 61.65  ? 135  GLU A OE1 1 
ATOM   755   O OE2 . GLU A 1 135 ? 136.784 101.997 76.944  1.00 61.65  ? 135  GLU A OE2 1 
ATOM   756   N N   . CYS A 1 136 ? 138.954 104.277 79.151  1.00 63.42  ? 136  CYS A N   1 
ATOM   757   C CA  . CYS A 1 136 ? 140.089 104.728 78.351  1.00 63.42  ? 136  CYS A CA  1 
ATOM   758   C C   . CYS A 1 136 ? 141.076 105.525 79.189  1.00 63.42  ? 136  CYS A C   1 
ATOM   759   O O   . CYS A 1 136 ? 142.260 105.599 78.845  1.00 63.42  ? 136  CYS A O   1 
ATOM   760   C CB  . CYS A 1 136 ? 139.620 105.556 77.154  1.00 63.42  ? 136  CYS A CB  1 
ATOM   761   S SG  . CYS A 1 136 ? 138.286 104.815 76.191  1.00 63.42  ? 136  CYS A SG  1 
ATOM   762   N N   . LEU A 1 137 ? 140.615 106.122 80.290  1.00 61.31  ? 137  LEU A N   1 
ATOM   763   C CA  . LEU A 1 137 ? 141.537 106.767 81.211  1.00 61.31  ? 137  LEU A CA  1 
ATOM   764   C C   . LEU A 1 137 ? 142.310 105.755 82.040  1.00 61.31  ? 137  LEU A C   1 
ATOM   765   O O   . LEU A 1 137 ? 143.418 106.063 82.476  1.00 61.31  ? 137  LEU A O   1 
ATOM   766   C CB  . LEU A 1 137 ? 140.781 107.739 82.117  1.00 61.31  ? 137  LEU A CB  1 
ATOM   767   C CG  . LEU A 1 137 ? 139.719 107.255 83.109  1.00 61.31  ? 137  LEU A CG  1 
ATOM   768   C CD1 . LEU A 1 137 ? 140.258 107.021 84.503  1.00 61.31  ? 137  LEU A CD1 1 
ATOM   769   C CD2 . LEU A 1 137 ? 138.652 108.277 83.185  1.00 61.31  ? 137  LEU A CD2 1 
ATOM   770   N N   . LYS A 1 138 ? 141.745 104.567 82.278  1.00 61.06  ? 138  LYS A N   1 
ATOM   771   C CA  . LYS A 1 138 ? 142.497 103.512 82.953  1.00 61.06  ? 138  LYS A CA  1 
ATOM   772   C C   . LYS A 1 138 ? 143.687 103.073 82.116  1.00 61.06  ? 138  LYS A C   1 
ATOM   773   O O   . LYS A 1 138 ? 144.746 102.747 82.659  1.00 61.06  ? 138  LYS A O   1 
ATOM   774   C CB  . LYS A 1 138 ? 141.604 102.304 83.252  1.00 61.06  ? 138  LYS A CB  1 
ATOM   775   C CG  . LYS A 1 138 ? 140.298 102.599 83.960  1.00 61.06  ? 138  LYS A CG  1 
ATOM   776   C CD  . LYS A 1 138 ? 140.477 103.432 85.216  1.00 61.06  ? 138  LYS A CD  1 
ATOM   777   C CE  . LYS A 1 138 ? 140.928 102.596 86.397  1.00 61.06  ? 138  LYS A CE  1 
ATOM   778   N NZ  . LYS A 1 138 ? 141.661 103.430 87.389  1.00 61.06  ? 138  LYS A NZ  1 
ATOM   779   N N   . LYS A 1 139 ? 143.531 103.069 80.794  1.00 63.77  ? 139  LYS A N   1 
ATOM   780   C CA  . LYS A 1 139 ? 144.650 102.764 79.915  1.00 63.77  ? 139  LYS A CA  1 
ATOM   781   C C   . LYS A 1 139 ? 145.553 103.977 79.729  1.00 63.77  ? 139  LYS A C   1 
ATOM   782   O O   . LYS A 1 139 ? 146.764 103.824 79.536  1.00 63.77  ? 139  LYS A O   1 
ATOM   783   C CB  . LYS A 1 139 ? 144.131 102.264 78.568  1.00 63.77  ? 139  LYS A CB  1 
ATOM   784   C CG  . LYS A 1 139 ? 144.975 101.165 77.940  1.00 63.77  ? 139  LYS A CG  1 
ATOM   785   C CD  . LYS A 1 139 ? 144.787 101.123 76.433  1.00 63.77  ? 139  LYS A CD  1 
ATOM   786   C CE  . LYS A 1 139 ? 145.347 99.840  75.842  1.00 63.77  ? 139  LYS A CE  1 
ATOM   787   N NZ  . LYS A 1 139 ? 144.886 99.620  74.441  1.00 63.77  ? 139  LYS A NZ  1 
ATOM   788   N N   . GLN A 1 140 ? 144.983 105.186 79.777  1.00 62.21  ? 140  GLN A N   1 
ATOM   789   C CA  . GLN A 1 140 ? 145.789 106.389 79.584  1.00 62.21  ? 140  GLN A CA  1 
ATOM   790   C C   . GLN A 1 140 ? 146.669 106.678 80.797  1.00 62.21  ? 140  GLN A C   1 
ATOM   791   O O   . GLN A 1 140 ? 147.819 107.104 80.635  1.00 62.21  ? 140  GLN A O   1 
ATOM   792   C CB  . GLN A 1 140 ? 144.887 107.583 79.252  1.00 62.21  ? 140  GLN A CB  1 
ATOM   793   C CG  . GLN A 1 140 ? 145.619 108.915 79.088  1.00 62.21  ? 140  GLN A CG  1 
ATOM   794   C CD  . GLN A 1 140 ? 146.076 109.167 77.658  1.00 62.21  ? 140  GLN A CD  1 
ATOM   795   O OE1 . GLN A 1 140 ? 145.940 108.305 76.788  1.00 62.21  ? 140  GLN A OE1 1 
ATOM   796   N NE2 . GLN A 1 140 ? 146.628 110.350 77.412  1.00 62.21  ? 140  GLN A NE2 1 
ATOM   797   N N   . MET A 1 141 ? 146.172 106.438 82.014  1.00 70.88  ? 141  MET A N   1 
ATOM   798   C CA  . MET A 1 141 ? 147.058 106.522 83.168  1.00 70.88  ? 141  MET A CA  1 
ATOM   799   C C   . MET A 1 141 ? 147.883 105.260 83.376  1.00 70.88  ? 141  MET A C   1 
ATOM   800   O O   . MET A 1 141 ? 148.700 105.228 84.298  1.00 70.88  ? 141  MET A O   1 
ATOM   801   C CB  . MET A 1 141 ? 146.290 106.827 84.457  1.00 70.88  ? 141  MET A CB  1 
ATOM   802   C CG  . MET A 1 141 ? 145.238 107.911 84.357  1.00 70.88  ? 141  MET A CG  1 
ATOM   803   S SD  . MET A 1 141 ? 144.206 107.931 85.833  1.00 70.88  ? 141  MET A SD  1 
ATOM   804   C CE  . MET A 1 141 ? 143.623 106.236 85.858  1.00 70.88  ? 141  MET A CE  1 
ATOM   805   N N   . ASP A 1 142 ? 147.679 104.213 82.570  1.00 68.46  ? 142  ASP A N   1 
ATOM   806   C CA  . ASP A 1 142 ? 148.515 103.024 82.709  1.00 68.46  ? 142  ASP A CA  1 
ATOM   807   C C   . ASP A 1 142 ? 149.870 103.200 82.037  1.00 68.46  ? 142  ASP A C   1 
ATOM   808   O O   . ASP A 1 142 ? 150.859 102.609 82.481  1.00 68.46  ? 142  ASP A O   1 
ATOM   809   C CB  . ASP A 1 142 ? 147.812 101.794 82.138  1.00 68.46  ? 142  ASP A CB  1 
ATOM   810   C CG  . ASP A 1 142 ? 148.097 100.539 82.941  1.00 68.46  ? 142  ASP A CG  1 
ATOM   811   O OD1 . ASP A 1 142 ? 148.806 100.633 83.966  1.00 68.46  ? 142  ASP A OD1 1 
ATOM   812   O OD2 . ASP A 1 142 ? 147.608 99.459  82.550  1.00 68.46  ? 142  ASP A OD2 1 
ATOM   813   N N   . ILE A 1 143 ? 149.940 103.986 80.960  1.00 63.91  ? 143  ILE A N   1 
ATOM   814   C CA  . ILE A 1 143 ? 151.245 104.307 80.389  1.00 63.91  ? 143  ILE A CA  1 
ATOM   815   C C   . ILE A 1 143 ? 151.964 105.306 81.290  1.00 63.91  ? 143  ILE A C   1 
ATOM   816   O O   . ILE A 1 143 ? 153.200 105.379 81.296  1.00 63.91  ? 143  ILE A O   1 
ATOM   817   C CB  . ILE A 1 143 ? 151.094 104.800 78.928  1.00 63.91  ? 143  ILE A CB  1 
ATOM   818   C CG1 . ILE A 1 143 ? 152.447 104.829 78.205  1.00 63.91  ? 143  ILE A CG1 1 
ATOM   819   C CG2 . ILE A 1 143 ? 150.419 106.163 78.851  1.00 63.91  ? 143  ILE A CG2 1 
ATOM   820   C CD1 . ILE A 1 143 ? 152.334 104.919 76.699  1.00 63.91  ? 143  ILE A CD1 1 
ATOM   821   N N   . LEU A 1 144 ? 151.205 106.068 82.085  1.00 63.64  ? 144  LEU A N   1 
ATOM   822   C CA  . LEU A 1 144 ? 151.772 106.921 83.122  1.00 63.64  ? 144  LEU A CA  1 
ATOM   823   C C   . LEU A 1 144 ? 152.490 106.103 84.186  1.00 63.64  ? 144  LEU A C   1 
ATOM   824   O O   . LEU A 1 144 ? 153.522 106.540 84.709  1.00 63.64  ? 144  LEU A O   1 
ATOM   825   C CB  . LEU A 1 144 ? 150.665 107.754 83.763  1.00 63.64  ? 144  LEU A CB  1 
ATOM   826   C CG  . LEU A 1 144 ? 151.040 108.702 84.899  1.00 63.64  ? 144  LEU A CG  1 
ATOM   827   C CD1 . LEU A 1 144 ? 151.827 109.913 84.401  1.00 63.64  ? 144  LEU A CD1 1 
ATOM   828   C CD2 . LEU A 1 144 ? 149.808 109.082 85.708  1.00 63.64  ? 144  LEU A CD2 1 
ATOM   829   N N   . ILE A 1 145 ? 151.953 104.920 84.511  1.00 68.70  ? 145  ILE A N   1 
ATOM   830   C CA  . ILE A 1 145 ? 152.608 103.986 85.425  1.00 68.70  ? 145  ILE A CA  1 
ATOM   831   C C   . ILE A 1 145 ? 153.981 103.582 84.903  1.00 68.70  ? 145  ILE A C   1 
ATOM   832   O O   . ILE A 1 145 ? 154.932 103.476 85.686  1.00 68.70  ? 145  ILE A O   1 
ATOM   833   C CB  . ILE A 1 145 ? 151.729 102.734 85.658  1.00 68.70  ? 145  ILE A CB  1 
ATOM   834   C CG1 . ILE A 1 145 ? 150.308 103.099 86.101  1.00 68.70  ? 145  ILE A CG1 1 
ATOM   835   C CG2 . ILE A 1 145 ? 152.345 101.799 86.696  1.00 68.70  ? 145  ILE A CG2 1 
ATOM   836   C CD1 . ILE A 1 145 ? 150.214 104.074 87.261  1.00 68.70  ? 145  ILE A CD1 1 
ATOM   837   N N   . GLU A 1 146 ? 154.120 103.402 83.586  1.00 66.69  ? 146  GLU A N   1 
ATOM   838   C CA  . GLU A 1 146 ? 155.425 103.105 83.004  1.00 66.69  ? 146  GLU A CA  1 
ATOM   839   C C   . GLU A 1 146 ? 156.344 104.321 83.077  1.00 66.69  ? 146  GLU A C   1 
ATOM   840   O O   . GLU A 1 146 ? 157.567 104.183 83.192  1.00 66.69  ? 146  GLU A O   1 
ATOM   841   C CB  . GLU A 1 146 ? 155.252 102.624 81.560  1.00 66.69  ? 146  GLU A CB  1 
ATOM   842   C CG  . GLU A 1 146 ? 156.482 101.956 80.943  1.00 66.69  ? 146  GLU A CG  1 
ATOM   843   C CD  . GLU A 1 146 ? 157.392 102.931 80.224  1.00 66.69  ? 146  GLU A CD  1 
ATOM   844   O OE1 . GLU A 1 146 ? 156.874 103.933 79.693  1.00 66.69  ? 146  GLU A OE1 1 
ATOM   845   O OE2 . GLU A 1 146 ? 158.619 102.699 80.191  1.00 66.69  ? 146  GLU A OE2 1 
ATOM   846   N N   . LEU A 1 147 ? 155.769 105.525 83.033  1.00 63.95  ? 147  LEU A N   1 
ATOM   847   C CA  . LEU A 1 147 ? 156.589 106.726 83.154  1.00 63.95  ? 147  LEU A CA  1 
ATOM   848   C C   . LEU A 1 147 ? 156.902 107.046 84.610  1.00 63.95  ? 147  LEU A C   1 
ATOM   849   O O   . LEU A 1 147 ? 158.054 107.345 84.949  1.00 63.95  ? 147  LEU A O   1 
ATOM   850   C CB  . LEU A 1 147 ? 155.905 107.916 82.481  1.00 63.95  ? 147  LEU A CB  1 
ATOM   851   C CG  . LEU A 1 147 ? 156.165 108.214 80.997  1.00 63.95  ? 147  LEU A CG  1 
ATOM   852   C CD1 . LEU A 1 147 ? 157.623 108.611 80.790  1.00 63.95  ? 147  LEU A CD1 1 
ATOM   853   C CD2 . LEU A 1 147 ? 155.778 107.079 80.057  1.00 63.95  ? 147  LEU A CD2 1 
ATOM   854   N N   . LYS A 1 148 ? 155.899 106.984 85.489  1.00 67.10  ? 148  LYS A N   1 
ATOM   855   C CA  . LYS A 1 148 ? 156.077 107.365 86.886  1.00 67.10  ? 148  LYS A CA  1 
ATOM   856   C C   . LYS A 1 148 ? 156.771 106.290 87.719  1.00 67.10  ? 148  LYS A C   1 
ATOM   857   O O   . LYS A 1 148 ? 156.959 106.477 88.923  1.00 67.10  ? 148  LYS A O   1 
ATOM   858   C CB  . LYS A 1 148 ? 154.730 107.754 87.511  1.00 67.10  ? 148  LYS A CB  1 
ATOM   859   C CG  . LYS A 1 148 ? 153.851 106.618 88.011  1.00 67.10  ? 148  LYS A CG  1 
ATOM   860   C CD  . LYS A 1 148 ? 152.388 106.993 87.891  1.00 67.10  ? 148  LYS A CD  1 
ATOM   861   C CE  . LYS A 1 148 ? 152.047 108.207 88.743  1.00 67.10  ? 148  LYS A CE  1 
ATOM   862   N NZ  . LYS A 1 148 ? 150.587 108.303 89.010  1.00 67.10  ? 148  LYS A NZ  1 
ATOM   863   N N   . ASP A 1 149 ? 157.169 105.175 87.111  1.00 67.00  ? 149  ASP A N   1 
ATOM   864   C CA  . ASP A 1 149 ? 158.042 104.221 87.773  1.00 67.00  ? 149  ASP A CA  1 
ATOM   865   C C   . ASP A 1 149 ? 159.514 104.430 87.454  1.00 67.00  ? 149  ASP A C   1 
ATOM   866   O O   . ASP A 1 149 ? 160.357 104.173 88.318  1.00 67.00  ? 149  ASP A O   1 
ATOM   867   C CB  . ASP A 1 149 ? 157.656 102.782 87.398  1.00 67.00  ? 149  ASP A CB  1 
ATOM   868   C CG  . ASP A 1 149 ? 156.614 102.198 88.329  1.00 67.00  ? 149  ASP A CG  1 
ATOM   869   O OD1 . ASP A 1 149 ? 156.588 100.961 88.489  1.00 67.00  ? 149  ASP A OD1 1 
ATOM   870   O OD2 . ASP A 1 149 ? 155.819 102.976 88.904  1.00 67.00  ? 149  ASP A OD2 1 
ATOM   871   N N   . ALA A 1 150 ? 159.842 104.900 86.248  1.00 68.75  ? 150  ALA A N   1 
ATOM   872   C CA  . ALA A 1 150 ? 161.233 104.991 85.829  1.00 68.75  ? 150  ALA A CA  1 
ATOM   873   C C   . ALA A 1 150 ? 161.846 106.364 86.055  1.00 68.75  ? 150  ALA A C   1 
ATOM   874   O O   . ALA A 1 150 ? 163.014 106.559 85.704  1.00 68.75  ? 150  ALA A O   1 
ATOM   875   C CB  . ALA A 1 150 ? 161.360 104.625 84.350  1.00 68.75  ? 150  ALA A CB  1 
ATOM   876   N N   . PHE A 1 151 ? 161.102 107.322 86.622  1.00 66.74  ? 151  PHE A N   1 
ATOM   877   C CA  . PHE A 1 151 ? 161.625 108.685 86.693  1.00 66.74  ? 151  PHE A CA  1 
ATOM   878   C C   . PHE A 1 151 ? 162.652 108.827 87.811  1.00 66.74  ? 151  PHE A C   1 
ATOM   879   O O   . PHE A 1 151 ? 163.443 109.777 87.816  1.00 66.74  ? 151  PHE A O   1 
ATOM   880   C CB  . PHE A 1 151 ? 160.486 109.697 86.864  1.00 66.74  ? 151  PHE A CB  1 
ATOM   881   C CG  . PHE A 1 151 ? 159.947 109.804 88.269  1.00 66.74  ? 151  PHE A CG  1 
ATOM   882   C CD1 . PHE A 1 151 ? 159.053 108.875 88.759  1.00 66.74  ? 151  PHE A CD1 1 
ATOM   883   C CD2 . PHE A 1 151 ? 160.287 110.890 89.072  1.00 66.74  ? 151  PHE A CD2 1 
ATOM   884   C CE1 . PHE A 1 151 ? 158.545 108.986 90.049  1.00 66.74  ? 151  PHE A CE1 1 
ATOM   885   C CE2 . PHE A 1 151 ? 159.784 111.014 90.360  1.00 66.74  ? 151  PHE A CE2 1 
ATOM   886   C CZ  . PHE A 1 151 ? 158.912 110.059 90.843  1.00 66.74  ? 151  PHE A CZ  1 
ATOM   887   N N   . LYS A 1 152 ? 162.647 107.904 88.775  1.00 64.43  ? 152  LYS A N   1 
ATOM   888   C CA  . LYS A 1 152 ? 163.675 107.895 89.807  1.00 64.43  ? 152  LYS A CA  1 
ATOM   889   C C   . LYS A 1 152 ? 164.643 106.731 89.647  1.00 64.43  ? 152  LYS A C   1 
ATOM   890   O O   . LYS A 1 152 ? 165.748 106.778 90.198  1.00 64.43  ? 152  LYS A O   1 
ATOM   891   C CB  . LYS A 1 152 ? 163.031 107.863 91.195  1.00 64.43  ? 152  LYS A CB  1 
ATOM   892   C CG  . LYS A 1 152 ? 163.896 108.459 92.297  1.00 64.43  ? 152  LYS A CG  1 
ATOM   893   C CD  . LYS A 1 152 ? 164.328 109.879 91.966  1.00 64.43  ? 152  LYS A CD  1 
ATOM   894   C CE  . LYS A 1 152 ? 163.154 110.842 92.003  1.00 64.43  ? 152  LYS A CE  1 
ATOM   895   N NZ  . LYS A 1 152 ? 163.611 112.240 92.201  1.00 64.43  ? 152  LYS A NZ  1 
ATOM   896   N N   . GLN A 1 153 ? 164.251 105.693 88.906  1.00 66.89  ? 153  GLN A N   1 
ATOM   897   C CA  . GLN A 1 153 ? 165.182 104.622 88.568  1.00 66.89  ? 153  GLN A CA  1 
ATOM   898   C C   . GLN A 1 153 ? 166.237 105.127 87.589  1.00 66.89  ? 153  GLN A C   1 
ATOM   899   O O   . GLN A 1 153 ? 167.441 104.949 87.810  1.00 66.89  ? 153  GLN A O   1 
ATOM   900   C CB  . GLN A 1 153 ? 164.403 103.433 87.993  1.00 66.89  ? 153  GLN A CB  1 
ATOM   901   C CG  . GLN A 1 153 ? 165.056 102.044 88.092  1.00 66.89  ? 153  GLN A CG  1 
ATOM   902   C CD  . GLN A 1 153 ? 166.357 101.902 87.328  1.00 66.89  ? 153  GLN A CD  1 
ATOM   903   O OE1 . GLN A 1 153 ? 166.437 102.232 86.145  1.00 66.89  ? 153  GLN A OE1 1 
ATOM   904   N NE2 . GLN A 1 153 ? 167.390 101.422 88.006  1.00 66.89  ? 153  GLN A NE2 1 
ATOM   905   N N   . LYS A 1 154 ? 165.802 105.756 86.498  1.00 61.98  ? 154  LYS A N   1 
ATOM   906   C CA  . LYS A 1 154 ? 166.720 106.262 85.488  1.00 61.98  ? 154  LYS A CA  1 
ATOM   907   C C   . LYS A 1 154 ? 167.388 107.571 85.884  1.00 61.98  ? 154  LYS A C   1 
ATOM   908   O O   . LYS A 1 154 ? 168.383 107.951 85.256  1.00 61.98  ? 154  LYS A O   1 
ATOM   909   C CB  . LYS A 1 154 ? 165.989 106.439 84.148  1.00 61.98  ? 154  LYS A CB  1 
ATOM   910   C CG  . LYS A 1 154 ? 165.470 105.140 83.513  1.00 61.98  ? 154  LYS A CG  1 
ATOM   911   C CD  . LYS A 1 154 ? 166.546 104.075 83.240  1.00 61.98  ? 154  LYS A CD  1 
ATOM   912   C CE  . LYS A 1 154 ? 167.753 104.602 82.453  1.00 61.98  ? 154  LYS A CE  1 
ATOM   913   N NZ  . LYS A 1 154 ? 168.623 103.497 81.969  1.00 61.98  ? 154  LYS A NZ  1 
ATOM   914   N N   . GLN A 1 155 ? 166.869 108.273 86.897  1.00 66.27  ? 155  GLN A N   1 
ATOM   915   C CA  . GLN A 1 155 ? 167.595 109.415 87.445  1.00 66.27  ? 155  GLN A CA  1 
ATOM   916   C C   . GLN A 1 155 ? 168.843 108.950 88.177  1.00 66.27  ? 155  GLN A C   1 
ATOM   917   O O   . GLN A 1 155 ? 169.864 109.647 88.192  1.00 66.27  ? 155  GLN A O   1 
ATOM   918   C CB  . GLN A 1 155 ? 166.691 110.221 88.376  1.00 66.27  ? 155  GLN A CB  1 
ATOM   919   C CG  . GLN A 1 155 ? 167.252 111.577 88.770  1.00 66.27  ? 155  GLN A CG  1 
ATOM   920   C CD  . GLN A 1 155 ? 166.213 112.471 89.414  1.00 66.27  ? 155  GLN A CD  1 
ATOM   921   O OE1 . GLN A 1 155 ? 165.061 112.079 89.582  1.00 66.27  ? 155  GLN A OE1 1 
ATOM   922   N NE2 . GLN A 1 155 ? 166.617 113.682 89.779  1.00 66.27  ? 155  GLN A NE2 1 
ATOM   923   N N   . ALA A 1 156 ? 168.784 107.759 88.770  1.00 62.03  ? 156  ALA A N   1 
ATOM   924   C CA  . ALA A 1 156 ? 169.955 107.132 89.360  1.00 62.03  ? 156  ALA A CA  1 
ATOM   925   C C   . ALA A 1 156 ? 170.884 106.525 88.317  1.00 62.03  ? 156  ALA A C   1 
ATOM   926   O O   . ALA A 1 156 ? 172.021 106.177 88.651  1.00 62.03  ? 156  ALA A O   1 
ATOM   927   C CB  . ALA A 1 156 ? 169.520 106.057 90.354  1.00 62.03  ? 156  ALA A CB  1 
ATOM   928   N N   . ASN A 1 157 ? 170.434 106.385 87.074  1.00 64.10  ? 157  ASN A N   1 
ATOM   929   C CA  . ASN A 1 157 ? 171.269 105.831 86.017  1.00 64.10  ? 157  ASN A CA  1 
ATOM   930   C C   . ASN A 1 157 ? 171.803 106.935 85.112  1.00 64.10  ? 157  ASN A C   1 
ATOM   931   O O   . ASN A 1 157 ? 172.224 106.678 83.984  1.00 64.10  ? 157  ASN A O   1 
ATOM   932   C CB  . ASN A 1 157 ? 170.484 104.809 85.194  1.00 64.10  ? 157  ASN A CB  1 
ATOM   933   C CG  . ASN A 1 157 ? 170.154 103.558 85.981  1.00 64.10  ? 157  ASN A CG  1 
ATOM   934   O OD1 . ASN A 1 157 ? 170.980 103.050 86.739  1.00 64.10  ? 157  ASN A OD1 1 
ATOM   935   N ND2 . ASN A 1 157 ? 168.941 103.053 85.803  1.00 64.10  ? 157  ASN A ND2 1 
ATOM   936   N N   . LYS A 1 280 ? 162.902 114.804 78.859  1.00 67.56  ? 280  LYS A N   1 
ATOM   937   C CA  . LYS A 1 280 ? 162.350 116.020 79.445  1.00 67.56  ? 280  LYS A CA  1 
ATOM   938   C C   . LYS A 1 280 ? 160.846 116.087 79.204  1.00 67.56  ? 280  LYS A C   1 
ATOM   939   O O   . LYS A 1 280 ? 160.206 117.100 79.480  1.00 67.56  ? 280  LYS A O   1 
ATOM   940   C CB  . LYS A 1 280 ? 163.035 117.264 78.867  1.00 67.56  ? 280  LYS A CB  1 
ATOM   941   C CG  . LYS A 1 280 ? 164.520 117.439 79.216  1.00 67.56  ? 280  LYS A CG  1 
ATOM   942   C CD  . LYS A 1 280 ? 164.902 116.872 80.581  1.00 67.56  ? 280  LYS A CD  1 
ATOM   943   C CE  . LYS A 1 280 ? 166.400 116.980 80.817  1.00 67.56  ? 280  LYS A CE  1 
ATOM   944   N NZ  . LYS A 1 280 ? 166.829 116.263 82.048  1.00 67.56  ? 280  LYS A NZ  1 
ATOM   945   N N   . LYS A 1 281 ? 160.289 114.993 78.688  1.00 66.28  ? 281  LYS A N   1 
ATOM   946   C CA  . LYS A 1 281 ? 158.860 114.884 78.428  1.00 66.28  ? 281  LYS A CA  1 
ATOM   947   C C   . LYS A 1 281 ? 158.056 114.533 79.672  1.00 66.28  ? 281  LYS A C   1 
ATOM   948   O O   . LYS A 1 281 ? 156.831 114.390 79.580  1.00 66.28  ? 281  LYS A O   1 
ATOM   949   C CB  . LYS A 1 281 ? 158.603 113.838 77.339  1.00 66.28  ? 281  LYS A CB  1 
ATOM   950   C CG  . LYS A 1 281 ? 159.013 112.427 77.729  1.00 66.28  ? 281  LYS A CG  1 
ATOM   951   C CD  . LYS A 1 281 ? 158.362 111.393 76.824  1.00 66.28  ? 281  LYS A CD  1 
ATOM   952   C CE  . LYS A 1 281 ? 159.236 110.158 76.677  1.00 66.28  ? 281  LYS A CE  1 
ATOM   953   N NZ  . LYS A 1 281 ? 160.218 110.306 75.566  1.00 66.28  ? 281  LYS A NZ  1 
ATOM   954   N N   . LEU A 1 282 ? 158.718 114.378 80.821  1.00 64.16  ? 282  LEU A N   1 
ATOM   955   C CA  . LEU A 1 282 ? 158.022 114.067 82.065  1.00 64.16  ? 282  LEU A CA  1 
ATOM   956   C C   . LEU A 1 282 ? 157.151 115.233 82.515  1.00 64.16  ? 282  LEU A C   1 
ATOM   957   O O   . LEU A 1 282 ? 156.060 115.032 83.062  1.00 64.16  ? 282  LEU A O   1 
ATOM   958   C CB  . LEU A 1 282 ? 159.046 113.677 83.138  1.00 64.16  ? 282  LEU A CB  1 
ATOM   959   C CG  . LEU A 1 282 ? 160.201 114.622 83.513  1.00 64.16  ? 282  LEU A CG  1 
ATOM   960   C CD1 . LEU A 1 282 ? 159.870 115.565 84.672  1.00 64.16  ? 282  LEU A CD1 1 
ATOM   961   C CD2 . LEU A 1 282 ? 161.465 113.829 83.812  1.00 64.16  ? 282  LEU A CD2 1 
ATOM   962   N N   . SER A 1 283 ? 157.613 116.463 82.285  1.00 62.07  ? 283  SER A N   1 
ATOM   963   C CA  . SER A 1 283 ? 156.809 117.630 82.615  1.00 62.07  ? 283  SER A CA  1 
ATOM   964   C C   . SER A 1 283 ? 155.719 117.880 81.584  1.00 62.07  ? 283  SER A C   1 
ATOM   965   O O   . SER A 1 283 ? 154.681 118.457 81.925  1.00 62.07  ? 283  SER A O   1 
ATOM   966   C CB  . SER A 1 283 ? 157.706 118.859 82.752  1.00 62.07  ? 283  SER A CB  1 
ATOM   967   O OG  . SER A 1 283 ? 158.693 118.650 83.746  1.00 62.07  ? 283  SER A OG  1 
ATOM   968   N N   . HIS A 1 284 ? 155.930 117.457 80.333  1.00 68.42  ? 284  HIS A N   1 
ATOM   969   C CA  . HIS A 1 284 ? 154.860 117.509 79.342  1.00 68.42  ? 284  HIS A CA  1 
ATOM   970   C C   . HIS A 1 284 ? 153.784 116.481 79.668  1.00 68.42  ? 284  HIS A C   1 
ATOM   971   O O   . HIS A 1 284 ? 152.605 116.681 79.349  1.00 68.42  ? 284  HIS A O   1 
ATOM   972   C CB  . HIS A 1 284 ? 155.453 117.302 77.938  1.00 68.42  ? 284  HIS A CB  1 
ATOM   973   C CG  . HIS A 1 284 ? 154.444 117.239 76.825  1.00 68.42  ? 284  HIS A CG  1 
ATOM   974   N ND1 . HIS A 1 284 ? 154.325 118.240 75.884  1.00 68.42  ? 284  HIS A ND1 1 
ATOM   975   C CD2 . HIS A 1 284 ? 153.587 116.262 76.438  1.00 68.42  ? 284  HIS A CD2 1 
ATOM   976   C CE1 . HIS A 1 284 ? 153.393 117.912 75.007  1.00 68.42  ? 284  HIS A CE1 1 
ATOM   977   N NE2 . HIS A 1 284 ? 152.929 116.716 75.321  1.00 68.42  ? 284  HIS A NE2 1 
ATOM   978   N N   . ALA A 1 285 ? 154.168 115.391 80.332  1.00 67.04  ? 285  ALA A N   1 
ATOM   979   C CA  . ALA A 1 285 ? 153.228 114.355 80.730  1.00 67.04  ? 285  ALA A CA  1 
ATOM   980   C C   . ALA A 1 285 ? 152.258 114.807 81.814  1.00 67.04  ? 285  ALA A C   1 
ATOM   981   O O   . ALA A 1 285 ? 151.202 114.186 81.964  1.00 67.04  ? 285  ALA A O   1 
ATOM   982   C CB  . ALA A 1 285 ? 153.990 113.119 81.214  1.00 67.04  ? 285  ALA A CB  1 
ATOM   983   N N   . GLU A 1 286 ? 152.582 115.866 82.559  1.00 68.75  ? 286  GLU A N   1 
ATOM   984   C CA  . GLU A 1 286 ? 151.712 116.304 83.645  1.00 68.75  ? 286  GLU A CA  1 
ATOM   985   C C   . GLU A 1 286 ? 150.445 116.961 83.108  1.00 68.75  ? 286  GLU A C   1 
ATOM   986   O O   . GLU A 1 286 ? 149.335 116.595 83.506  1.00 68.75  ? 286  GLU A O   1 
ATOM   987   C CB  . GLU A 1 286 ? 152.477 117.249 84.572  1.00 68.75  ? 286  GLU A CB  1 
ATOM   988   C CG  . GLU A 1 286 ? 153.895 116.779 84.869  1.00 68.75  ? 286  GLU A CG  1 
ATOM   989   C CD  . GLU A 1 286 ? 154.709 117.789 85.655  1.00 68.75  ? 286  GLU A CD  1 
ATOM   990   O OE1 . GLU A 1 286 ? 155.818 117.434 86.107  1.00 68.75  ? 286  GLU A OE1 1 
ATOM   991   O OE2 . GLU A 1 286 ? 154.245 118.935 85.822  1.00 68.75  ? 286  GLU A OE2 1 
ATOM   992   N N   . LYS A 1 287 ? 150.592 117.897 82.160  1.00 67.48  ? 287  LYS A N   1 
ATOM   993   C CA  . LYS A 1 287 ? 149.445 118.557 81.529  1.00 67.48  ? 287  LYS A CA  1 
ATOM   994   C C   . LYS A 1 287 ? 148.593 117.554 80.748  1.00 67.48  ? 287  LYS A C   1 
ATOM   995   O O   . LYS A 1 287 ? 147.382 117.746 80.589  1.00 67.48  ? 287  LYS A O   1 
ATOM   996   C CB  . LYS A 1 287 ? 149.955 119.687 80.623  1.00 67.48  ? 287  LYS A CB  1 
ATOM   997   C CG  . LYS A 1 287 ? 148.958 120.455 79.719  1.00 67.48  ? 287  LYS A CG  1 
ATOM   998   C CD  . LYS A 1 287 ? 147.674 120.938 80.398  1.00 67.48  ? 287  LYS A CD  1 
ATOM   999   C CE  . LYS A 1 287 ? 147.005 122.019 79.553  1.00 67.48  ? 287  LYS A CE  1 
ATOM   1000  N NZ  . LYS A 1 287 ? 145.776 122.582 80.177  1.00 67.48  ? 287  LYS A NZ  1 
ATOM   1001  N N   . MET A 1 288 ? 149.202 116.450 80.300  1.00 67.66  ? 288  MET A N   1 
ATOM   1002  C CA  . MET A 1 288 ? 148.443 115.376 79.668  1.00 67.66  ? 288  MET A CA  1 
ATOM   1003  C C   . MET A 1 288 ? 147.467 114.712 80.635  1.00 67.66  ? 288  MET A C   1 
ATOM   1004  O O   . MET A 1 288 ? 146.482 114.110 80.194  1.00 67.66  ? 288  MET A O   1 
ATOM   1005  C CB  . MET A 1 288 ? 149.393 114.322 79.100  1.00 67.66  ? 288  MET A CB  1 
ATOM   1006  C CG  . MET A 1 288 ? 150.264 114.796 77.949  1.00 67.66  ? 288  MET A CG  1 
ATOM   1007  S SD  . MET A 1 288 ? 149.308 115.359 76.529  1.00 67.66  ? 288  MET A SD  1 
ATOM   1008  C CE  . MET A 1 288 ? 148.567 113.811 76.002  1.00 67.66  ? 288  MET A CE  1 
ATOM   1009  N N   . ILE A 1 289 ? 147.720 114.797 81.943  1.00 63.97  ? 289  ILE A N   1 
ATOM   1010  C CA  . ILE A 1 289 ? 146.799 114.216 82.914  1.00 63.97  ? 289  ILE A CA  1 
ATOM   1011  C C   . ILE A 1 289 ? 146.245 115.221 83.920  1.00 63.97  ? 289  ILE A C   1 
ATOM   1012  O O   . ILE A 1 289 ? 145.243 114.918 84.583  1.00 63.97  ? 289  ILE A O   1 
ATOM   1013  C CB  . ILE A 1 289 ? 147.460 113.050 83.667  1.00 63.97  ? 289  ILE A CB  1 
ATOM   1014  C CG1 . ILE A 1 289 ? 148.863 113.444 84.121  1.00 63.97  ? 289  ILE A CG1 1 
ATOM   1015  C CG2 . ILE A 1 289 ? 147.498 111.803 82.790  1.00 63.97  ? 289  ILE A CG2 1 
ATOM   1016  C CD1 . ILE A 1 289 ? 149.358 112.710 85.324  1.00 63.97  ? 289  ILE A CD1 1 
ATOM   1017  N N   . LYS A 1 290 ? 146.879 116.388 84.081  1.00 61.80  ? 290  LYS A N   1 
ATOM   1018  C CA  . LYS A 1 290 ? 146.296 117.438 84.916  1.00 61.80  ? 290  LYS A CA  1 
ATOM   1019  C C   . LYS A 1 290 ? 144.982 117.930 84.330  1.00 61.80  ? 290  LYS A C   1 
ATOM   1020  O O   . LYS A 1 290 ? 143.912 117.718 84.910  1.00 61.80  ? 290  LYS A O   1 
ATOM   1021  C CB  . LYS A 1 290 ? 147.263 118.614 85.083  1.00 61.80  ? 290  LYS A CB  1 
ATOM   1022  C CG  . LYS A 1 290 ? 148.450 118.379 86.000  1.00 61.80  ? 290  LYS A CG  1 
ATOM   1023  C CD  . LYS A 1 290 ? 148.895 119.677 86.648  1.00 61.80  ? 290  LYS A CD  1 
ATOM   1024  C CE  . LYS A 1 290 ? 150.408 119.797 86.649  1.00 61.80  ? 290  LYS A CE  1 
ATOM   1025  N NZ  . LYS A 1 290 ? 150.851 121.217 86.650  1.00 61.80  ? 290  LYS A NZ  1 
ATOM   1026  N N   . GLY A 1 291 ? 145.044 118.550 83.148  1.00 58.86  ? 291  GLY A N   1 
ATOM   1027  C CA  . GLY A 1 291 ? 143.863 119.099 82.503  1.00 58.86  ? 291  GLY A CA  1 
ATOM   1028  C C   . GLY A 1 291 ? 142.830 118.067 82.109  1.00 58.86  ? 291  GLY A C   1 
ATOM   1029  O O   . GLY A 1 291 ? 141.658 118.415 81.938  1.00 58.86  ? 291  GLY A O   1 
ATOM   1030  N N   . ALA A 1 292 ? 143.237 116.806 81.966  1.00 58.34  ? 292  ALA A N   1 
ATOM   1031  C CA  . ALA A 1 292 ? 142.269 115.736 81.776  1.00 58.34  ? 292  ALA A CA  1 
ATOM   1032  C C   . ALA A 1 292 ? 141.429 115.539 83.030  1.00 58.34  ? 292  ALA A C   1 
ATOM   1033  O O   . ALA A 1 292 ? 140.218 115.778 83.026  1.00 58.34  ? 292  ALA A O   1 
ATOM   1034  C CB  . ALA A 1 292 ? 142.990 114.439 81.399  1.00 58.34  ? 292  ALA A CB  1 
ATOM   1035  N N   . LEU A 1 293 ? 142.070 115.172 84.134  1.00 57.30  ? 293  LEU A N   1 
ATOM   1036  C CA  . LEU A 1 293 ? 141.336 114.739 85.316  1.00 57.30  ? 293  LEU A CA  1 
ATOM   1037  C C   . LEU A 1 293 ? 140.950 115.876 86.253  1.00 57.30  ? 293  LEU A C   1 
ATOM   1038  O O   . LEU A 1 293 ? 140.445 115.603 87.346  1.00 57.30  ? 293  LEU A O   1 
ATOM   1039  C CB  . LEU A 1 293 ? 142.142 113.688 86.086  1.00 57.30  ? 293  LEU A CB  1 
ATOM   1040  C CG  . LEU A 1 293 ? 141.928 112.204 85.749  1.00 57.30  ? 293  LEU A CG  1 
ATOM   1041  C CD1 . LEU A 1 293 ? 140.497 111.791 86.055  1.00 57.30  ? 293  LEU A CD1 1 
ATOM   1042  C CD2 . LEU A 1 293 ? 142.292 111.843 84.313  1.00 57.30  ? 293  LEU A CD2 1 
ATOM   1043  N N   . THR A 1 294 ? 141.163 117.135 85.872  1.00 54.95  ? 294  THR A N   1 
ATOM   1044  C CA  . THR A 1 294 ? 140.601 118.229 86.657  1.00 54.95  ? 294  THR A CA  1 
ATOM   1045  C C   . THR A 1 294 ? 139.096 118.352 86.435  1.00 54.95  ? 294  THR A C   1 
ATOM   1046  O O   . THR A 1 294 ? 138.305 118.211 87.373  1.00 54.95  ? 294  THR A O   1 
ATOM   1047  C CB  . THR A 1 294 ? 141.320 119.539 86.330  1.00 54.95  ? 294  THR A CB  1 
ATOM   1048  O OG1 . THR A 1 294 ? 141.554 119.619 84.919  1.00 54.95  ? 294  THR A OG1 1 
ATOM   1049  C CG2 . THR A 1 294 ? 142.618 119.678 87.116  1.00 54.95  ? 294  THR A CG2 1 
ATOM   1050  N N   . GLU A 1 295 ? 138.677 118.602 85.198  1.00 56.90  ? 295  GLU A N   1 
ATOM   1051  C CA  . GLU A 1 295 ? 137.258 118.768 84.911  1.00 56.90  ? 295  GLU A CA  1 
ATOM   1052  C C   . GLU A 1 295 ? 136.544 117.449 84.664  1.00 56.90  ? 295  GLU A C   1 
ATOM   1053  O O   . GLU A 1 295 ? 135.309 117.430 84.631  1.00 56.90  ? 295  GLU A O   1 
ATOM   1054  C CB  . GLU A 1 295 ? 137.061 119.687 83.700  1.00 56.90  ? 295  GLU A CB  1 
ATOM   1055  C CG  . GLU A 1 295 ? 137.135 121.173 84.015  1.00 56.90  ? 295  GLU A CG  1 
ATOM   1056  C CD  . GLU A 1 295 ? 137.820 121.965 82.917  1.00 56.90  ? 295  GLU A CD  1 
ATOM   1057  O OE1 . GLU A 1 295 ? 137.269 122.044 81.800  1.00 56.90  ? 295  GLU A OE1 1 
ATOM   1058  O OE2 . GLU A 1 295 ? 138.906 122.520 83.172  1.00 56.90  ? 295  GLU A OE2 1 
ATOM   1059  N N   . LEU A 1 296 ? 137.286 116.354 84.483  1.00 53.92  ? 296  LEU A N   1 
ATOM   1060  C CA  . LEU A 1 296 ? 136.654 115.043 84.402  1.00 53.92  ? 296  LEU A CA  1 
ATOM   1061  C C   . LEU A 1 296 ? 136.069 114.645 85.749  1.00 53.92  ? 296  LEU A C   1 
ATOM   1062  O O   . LEU A 1 296 ? 135.060 113.934 85.808  1.00 53.92  ? 296  LEU A O   1 
ATOM   1063  C CB  . LEU A 1 296 ? 137.663 114.010 83.908  1.00 53.92  ? 296  LEU A CB  1 
ATOM   1064  C CG  . LEU A 1 296 ? 137.329 112.530 83.734  1.00 53.92  ? 296  LEU A CG  1 
ATOM   1065  C CD1 . LEU A 1 296 ? 135.988 112.317 83.075  1.00 53.92  ? 296  LEU A CD1 1 
ATOM   1066  C CD2 . LEU A 1 296 ? 138.408 111.941 82.866  1.00 53.92  ? 296  LEU A CD2 1 
ATOM   1067  N N   . PHE A 1 297 ? 136.692 115.097 86.840  1.00 56.79  ? 297  PHE A N   1 
ATOM   1068  C CA  . PHE A 1 297 ? 136.020 115.056 88.132  1.00 56.79  ? 297  PHE A CA  1 
ATOM   1069  C C   . PHE A 1 297 ? 134.775 115.930 88.111  1.00 56.79  ? 297  PHE A C   1 
ATOM   1070  O O   . PHE A 1 297 ? 133.702 115.500 88.549  1.00 56.79  ? 297  PHE A O   1 
ATOM   1071  C CB  . PHE A 1 297 ? 136.964 115.522 89.242  1.00 56.79  ? 297  PHE A CB  1 
ATOM   1072  C CG  . PHE A 1 297 ? 136.419 115.333 90.640  1.00 56.79  ? 297  PHE A CG  1 
ATOM   1073  C CD1 . PHE A 1 297 ? 136.880 116.122 91.678  1.00 56.79  ? 297  PHE A CD1 1 
ATOM   1074  C CD2 . PHE A 1 297 ? 135.507 114.326 90.932  1.00 56.79  ? 297  PHE A CD2 1 
ATOM   1075  C CE1 . PHE A 1 297 ? 136.407 115.959 92.964  1.00 56.79  ? 297  PHE A CE1 1 
ATOM   1076  C CE2 . PHE A 1 297 ? 135.027 114.154 92.220  1.00 56.79  ? 297  PHE A CE2 1 
ATOM   1077  C CZ  . PHE A 1 297 ? 135.483 114.970 93.237  1.00 56.79  ? 297  PHE A CZ  1 
ATOM   1078  N N   . LYS A 1 298 ? 134.890 117.147 87.573  1.00 53.02  ? 298  LYS A N   1 
ATOM   1079  C CA  . LYS A 1 298 ? 133.763 118.069 87.616  1.00 53.02  ? 298  LYS A CA  1 
ATOM   1080  C C   . LYS A 1 298 ? 132.661 117.667 86.651  1.00 53.02  ? 298  LYS A C   1 
ATOM   1081  O O   . LYS A 1 298 ? 131.525 118.120 86.801  1.00 53.02  ? 298  LYS A O   1 
ATOM   1082  C CB  . LYS A 1 298 ? 134.233 119.498 87.345  1.00 53.02  ? 298  LYS A CB  1 
ATOM   1083  C CG  . LYS A 1 298 ? 134.823 120.220 88.569  1.00 53.02  ? 298  LYS A CG  1 
ATOM   1084  C CD  . LYS A 1 298 ? 134.195 119.740 89.880  1.00 53.02  ? 298  LYS A CD  1 
ATOM   1085  C CE  . LYS A 1 298 ? 134.537 120.613 91.066  1.00 53.02  ? 298  LYS A CE  1 
ATOM   1086  N NZ  . LYS A 1 298 ? 133.890 120.130 92.320  1.00 53.02  ? 298  LYS A NZ  1 
ATOM   1087  N N   . GLY A 1 299 ? 132.963 116.810 85.674  1.00 50.35  ? 299  GLY A N   1 
ATOM   1088  C CA  . GLY A 1 299 ? 131.901 116.179 84.914  1.00 50.35  ? 299  GLY A CA  1 
ATOM   1089  C C   . GLY A 1 299 ? 131.070 115.237 85.758  1.00 50.35  ? 299  GLY A C   1 
ATOM   1090  O O   . GLY A 1 299 ? 129.875 115.057 85.503  1.00 50.35  ? 299  GLY A O   1 
ATOM   1091  N N   . LEU A 1 300 ? 131.685 114.627 86.771  1.00 50.39  ? 300  LEU A N   1 
ATOM   1092  C CA  . LEU A 1 300 ? 130.947 113.802 87.716  1.00 50.39  ? 300  LEU A CA  1 
ATOM   1093  C C   . LEU A 1 300 ? 130.256 114.644 88.781  1.00 50.39  ? 300  LEU A C   1 
ATOM   1094  O O   . LEU A 1 300 ? 129.133 114.319 89.180  1.00 50.39  ? 300  LEU A O   1 
ATOM   1095  C CB  . LEU A 1 300 ? 131.891 112.787 88.359  1.00 50.39  ? 300  LEU A CB  1 
ATOM   1096  C CG  . LEU A 1 300 ? 132.781 112.039 87.363  1.00 50.39  ? 300  LEU A CG  1 
ATOM   1097  C CD1 . LEU A 1 300 ? 133.798 111.155 88.058  1.00 50.39  ? 300  LEU A CD1 1 
ATOM   1098  C CD2 . LEU A 1 300 ? 131.931 111.212 86.428  1.00 50.39  ? 300  LEU A CD2 1 
ATOM   1099  N N   . ASN A 1 301 ? 130.901 115.721 89.252  1.00 53.72  ? 301  ASN A N   1 
ATOM   1100  C CA  . ASN A 1 301 ? 130.232 116.648 90.164  1.00 53.72  ? 301  ASN A CA  1 
ATOM   1101  C C   . ASN A 1 301 ? 129.075 117.375 89.494  1.00 53.72  ? 301  ASN A C   1 
ATOM   1102  O O   . ASN A 1 301 ? 128.131 117.783 90.178  1.00 53.72  ? 301  ASN A O   1 
ATOM   1103  C CB  . ASN A 1 301 ? 131.216 117.666 90.746  1.00 53.72  ? 301  ASN A CB  1 
ATOM   1104  C CG  . ASN A 1 301 ? 132.336 117.020 91.550  1.00 53.72  ? 301  ASN A CG  1 
ATOM   1105  O OD1 . ASN A 1 301 ? 133.432 116.793 91.045  1.00 53.72  ? 301  ASN A OD1 1 
ATOM   1106  N ND2 . ASN A 1 301 ? 132.066 116.744 92.819  1.00 53.72  ? 301  ASN A ND2 1 
ATOM   1107  N N   . TYR A 1 302 ? 129.133 117.568 88.174  1.00 54.70  ? 302  TYR A N   1 
ATOM   1108  C CA  . TYR A 1 302 ? 127.941 118.016 87.463  1.00 54.70  ? 302  TYR A CA  1 
ATOM   1109  C C   . TYR A 1 302 ? 126.896 116.910 87.426  1.00 54.70  ? 302  TYR A C   1 
ATOM   1110  O O   . TYR A 1 302 ? 125.694 117.180 87.525  1.00 54.70  ? 302  TYR A O   1 
ATOM   1111  C CB  . TYR A 1 302 ? 128.288 118.464 86.039  1.00 54.70  ? 302  TYR A CB  1 
ATOM   1112  C CG  . TYR A 1 302 ? 129.131 119.725 85.923  1.00 54.70  ? 302  TYR A CG  1 
ATOM   1113  C CD1 . TYR A 1 302 ? 129.285 120.595 86.997  1.00 54.70  ? 302  TYR A CD1 1 
ATOM   1114  C CD2 . TYR A 1 302 ? 129.792 120.028 84.737  1.00 54.70  ? 302  TYR A CD2 1 
ATOM   1115  C CE1 . TYR A 1 302 ? 130.063 121.733 86.888  1.00 54.70  ? 302  TYR A CE1 1 
ATOM   1116  C CE2 . TYR A 1 302 ? 130.568 121.164 84.619  1.00 54.70  ? 302  TYR A CE2 1 
ATOM   1117  C CZ  . TYR A 1 302 ? 130.700 122.011 85.698  1.00 54.70  ? 302  TYR A CZ  1 
ATOM   1118  O OH  . TYR A 1 302 ? 131.472 123.143 85.584  1.00 54.70  ? 302  TYR A OH  1 
ATOM   1119  N N   . LEU A 1 303 ? 127.340 115.658 87.304  1.00 52.84  ? 303  LEU A N   1 
ATOM   1120  C CA  . LEU A 1 303 ? 126.416 114.535 87.228  1.00 52.84  ? 303  LEU A CA  1 
ATOM   1121  C C   . LEU A 1 303 ? 125.752 114.246 88.566  1.00 52.84  ? 303  LEU A C   1 
ATOM   1122  O O   . LEU A 1 303 ? 124.600 113.802 88.595  1.00 52.84  ? 303  LEU A O   1 
ATOM   1123  C CB  . LEU A 1 303 ? 127.144 113.293 86.717  1.00 52.84  ? 303  LEU A CB  1 
ATOM   1124  C CG  . LEU A 1 303 ? 126.290 112.125 86.216  1.00 52.84  ? 303  LEU A CG  1 
ATOM   1125  C CD1 . LEU A 1 303 ? 125.058 112.597 85.449  1.00 52.84  ? 303  LEU A CD1 1 
ATOM   1126  C CD2 . LEU A 1 303 ? 127.136 111.211 85.353  1.00 52.84  ? 303  LEU A CD2 1 
ATOM   1127  N N   . LYS A 1 304 ? 126.456 114.474 89.676  1.00 52.81  ? 304  LYS A N   1 
ATOM   1128  C CA  . LYS A 1 304 ? 125.793 114.434 90.974  1.00 52.81  ? 304  LYS A CA  1 
ATOM   1129  C C   . LYS A 1 304 ? 124.825 115.598 91.116  1.00 52.81  ? 304  LYS A C   1 
ATOM   1130  O O   . LYS A 1 304 ? 123.713 115.431 91.630  1.00 52.81  ? 304  LYS A O   1 
ATOM   1131  C CB  . LYS A 1 304 ? 126.826 114.459 92.101  1.00 52.81  ? 304  LYS A CB  1 
ATOM   1132  C CG  . LYS A 1 304 ? 127.866 113.359 92.027  1.00 52.81  ? 304  LYS A CG  1 
ATOM   1133  C CD  . LYS A 1 304 ? 129.222 113.851 92.495  1.00 52.81  ? 304  LYS A CD  1 
ATOM   1134  C CE  . LYS A 1 304 ? 130.317 112.880 92.105  1.00 52.81  ? 304  LYS A CE  1 
ATOM   1135  N NZ  . LYS A 1 304 ? 131.652 113.351 92.551  1.00 52.81  ? 304  LYS A NZ  1 
ATOM   1136  N N   . THR A 1 305 ? 125.229 116.783 90.644  1.00 53.28  ? 305  THR A N   1 
ATOM   1137  C CA  . THR A 1 305 ? 124.339 117.937 90.631  1.00 53.28  ? 305  THR A CA  1 
ATOM   1138  C C   . THR A 1 305 ? 123.191 117.725 89.655  1.00 53.28  ? 305  THR A C   1 
ATOM   1139  O O   . THR A 1 305 ? 122.089 118.245 89.868  1.00 53.28  ? 305  THR A O   1 
ATOM   1140  C CB  . THR A 1 305 ? 125.133 119.195 90.273  1.00 53.28  ? 305  THR A CB  1 
ATOM   1141  O OG1 . THR A 1 305 ? 126.345 119.221 91.036  1.00 53.28  ? 305  THR A OG1 1 
ATOM   1142  C CG2 . THR A 1 305 ? 124.346 120.452 90.604  1.00 53.28  ? 305  THR A CG2 1 
ATOM   1143  N N   . TYR A 1 306 ? 123.427 116.950 88.594  1.00 50.38  ? 306  TYR A N   1 
ATOM   1144  C CA  . TYR A 1 306 ? 122.333 116.501 87.743  1.00 50.38  ? 306  TYR A CA  1 
ATOM   1145  C C   . TYR A 1 306 ? 121.375 115.604 88.515  1.00 50.38  ? 306  TYR A C   1 
ATOM   1146  O O   . TYR A 1 306 ? 120.155 115.704 88.350  1.00 50.38  ? 306  TYR A O   1 
ATOM   1147  C CB  . TYR A 1 306 ? 122.893 115.770 86.522  1.00 50.38  ? 306  TYR A CB  1 
ATOM   1148  C CG  . TYR A 1 306 ? 121.855 115.154 85.617  1.00 50.38  ? 306  TYR A CG  1 
ATOM   1149  C CD1 . TYR A 1 306 ? 121.536 113.803 85.703  1.00 50.38  ? 306  TYR A CD1 1 
ATOM   1150  C CD2 . TYR A 1 306 ? 121.210 115.917 84.664  1.00 50.38  ? 306  TYR A CD2 1 
ATOM   1151  C CE1 . TYR A 1 306 ? 120.588 113.241 84.876  1.00 50.38  ? 306  TYR A CE1 1 
ATOM   1152  C CE2 . TYR A 1 306 ? 120.269 115.363 83.829  1.00 50.38  ? 306  TYR A CE2 1 
ATOM   1153  C CZ  . TYR A 1 306 ? 119.956 114.027 83.944  1.00 50.38  ? 306  TYR A CZ  1 
ATOM   1154  O OH  . TYR A 1 306 ? 119.016 113.480 83.105  1.00 50.38  ? 306  TYR A OH  1 
ATOM   1155  N N   . ARG A 1 307 ? 121.912 114.721 89.363  1.00 52.65  ? 307  ARG A N   1 
ATOM   1156  C CA  . ARG A 1 307 ? 121.068 113.794 90.110  1.00 52.65  ? 307  ARG A CA  1 
ATOM   1157  C C   . ARG A 1 307 ? 120.284 114.519 91.194  1.00 52.65  ? 307  ARG A C   1 
ATOM   1158  O O   . ARG A 1 307 ? 119.079 114.294 91.354  1.00 52.65  ? 307  ARG A O   1 
ATOM   1159  C CB  . ARG A 1 307 ? 121.915 112.675 90.719  1.00 52.65  ? 307  ARG A CB  1 
ATOM   1160  C CG  . ARG A 1 307 ? 121.199 111.877 91.812  1.00 52.65  ? 307  ARG A CG  1 
ATOM   1161  C CD  . ARG A 1 307 ? 122.064 110.775 92.415  1.00 52.65  ? 307  ARG A CD  1 
ATOM   1162  N NE  . ARG A 1 307 ? 123.386 111.239 92.819  1.00 52.65  ? 307  ARG A NE  1 
ATOM   1163  C CZ  . ARG A 1 307 ? 124.496 110.528 92.672  1.00 52.65  ? 307  ARG A CZ  1 
ATOM   1164  N NH1 . ARG A 1 307 ? 124.442 109.322 92.129  1.00 52.65  ? 307  ARG A NH1 1 
ATOM   1165  N NH2 . ARG A 1 307 ? 125.658 111.020 93.063  1.00 52.65  ? 307  ARG A NH2 1 
ATOM   1166  N N   . ASN A 1 308 ? 120.958 115.404 91.938  1.00 53.44  ? 308  ASN A N   1 
ATOM   1167  C CA  . ASN A 1 308 ? 120.327 116.121 93.042  1.00 53.44  ? 308  ASN A CA  1 
ATOM   1168  C C   . ASN A 1 308 ? 119.222 117.050 92.566  1.00 53.44  ? 308  ASN A C   1 
ATOM   1169  O O   . ASN A 1 308 ? 118.153 117.098 93.186  1.00 53.44  ? 308  ASN A O   1 
ATOM   1170  C CB  . ASN A 1 308 ? 121.372 116.927 93.807  1.00 53.44  ? 308  ASN A CB  1 
ATOM   1171  C CG  . ASN A 1 308 ? 122.443 116.062 94.403  1.00 53.44  ? 308  ASN A CG  1 
ATOM   1172  O OD1 . ASN A 1 308 ? 122.156 115.043 95.024  1.00 53.44  ? 308  ASN A OD1 1 
ATOM   1173  N ND2 . ASN A 1 308 ? 123.695 116.450 94.200  1.00 53.44  ? 308  ASN A ND2 1 
ATOM   1174  N N   . LEU A 1 309 ? 119.461 117.784 91.473  1.00 51.27  ? 309  LEU A N   1 
ATOM   1175  C CA  . LEU A 1 309 ? 118.444 118.680 90.930  1.00 51.27  ? 309  LEU A CA  1 
ATOM   1176  C C   . LEU A 1 309 ? 117.246 117.914 90.393  1.00 51.27  ? 309  LEU A C   1 
ATOM   1177  O O   . LEU A 1 309 ? 116.118 118.407 90.473  1.00 51.27  ? 309  LEU A O   1 
ATOM   1178  C CB  . LEU A 1 309 ? 119.034 119.567 89.832  1.00 51.27  ? 309  LEU A CB  1 
ATOM   1179  C CG  . LEU A 1 309 ? 119.650 120.928 90.185  1.00 51.27  ? 309  LEU A CG  1 
ATOM   1180  C CD1 . LEU A 1 309 ? 120.704 120.872 91.286  1.00 51.27  ? 309  LEU A CD1 1 
ATOM   1181  C CD2 . LEU A 1 309 ? 120.217 121.579 88.931  1.00 51.27  ? 309  LEU A CD2 1 
ATOM   1182  N N   . ASN A 1 310 ? 117.460 116.710 89.867  1.00 51.45  ? 310  ASN A N   1 
ATOM   1183  C CA  . ASN A 1 310 ? 116.342 115.883 89.440  1.00 51.45  ? 310  ASN A CA  1 
ATOM   1184  C C   . ASN A 1 310 ? 115.563 115.302 90.615  1.00 51.45  ? 310  ASN A C   1 
ATOM   1185  O O   . ASN A 1 310 ? 114.344 115.143 90.512  1.00 51.45  ? 310  ASN A O   1 
ATOM   1186  C CB  . ASN A 1 310 ? 116.838 114.770 88.517  1.00 51.45  ? 310  ASN A CB  1 
ATOM   1187  C CG  . ASN A 1 310 ? 117.334 115.299 87.183  1.00 51.45  ? 310  ASN A CG  1 
ATOM   1188  O OD1 . ASN A 1 310 ? 118.153 114.671 86.513  1.00 51.45  ? 310  ASN A OD1 1 
ATOM   1189  N ND2 . ASN A 1 310 ? 116.848 116.468 86.800  1.00 51.45  ? 310  ASN A ND2 1 
ATOM   1190  N N   . ILE A 1 311 ? 116.229 114.980 91.726  1.00 54.91  ? 311  ILE A N   1 
ATOM   1191  C CA  . ILE A 1 311 ? 115.499 114.727 92.964  1.00 54.91  ? 311  ILE A CA  1 
ATOM   1192  C C   . ILE A 1 311 ? 114.845 116.010 93.456  1.00 54.91  ? 311  ILE A C   1 
ATOM   1193  O O   . ILE A 1 311 ? 113.691 116.007 93.901  1.00 54.91  ? 311  ILE A O   1 
ATOM   1194  C CB  . ILE A 1 311 ? 116.421 114.106 94.029  1.00 54.91  ? 311  ILE A CB  1 
ATOM   1195  C CG1 . ILE A 1 311 ? 117.089 112.844 93.490  1.00 54.91  ? 311  ILE A CG1 1 
ATOM   1196  C CG2 . ILE A 1 311 ? 115.644 113.765 95.285  1.00 54.91  ? 311  ILE A CG2 1 
ATOM   1197  C CD1 . ILE A 1 311 ? 116.102 111.788 93.067  1.00 54.91  ? 311  ILE A CD1 1 
ATOM   1198  N N   . LEU A 1 312 ? 115.557 117.137 93.345  1.00 52.77  ? 312  LEU A N   1 
ATOM   1199  C CA  . LEU A 1 312 ? 114.942 118.432 93.620  1.00 52.77  ? 312  LEU A CA  1 
ATOM   1200  C C   . LEU A 1 312 ? 113.865 118.786 92.601  1.00 52.77  ? 312  LEU A C   1 
ATOM   1201  O O   . LEU A 1 312 ? 113.007 119.624 92.890  1.00 52.77  ? 312  LEU A O   1 
ATOM   1202  C CB  . LEU A 1 312 ? 116.001 119.535 93.663  1.00 52.77  ? 312  LEU A CB  1 
ATOM   1203  C CG  . LEU A 1 312 ? 116.647 119.776 95.029  1.00 52.77  ? 312  LEU A CG  1 
ATOM   1204  C CD1 . LEU A 1 312 ? 117.693 120.877 94.956  1.00 52.77  ? 312  LEU A CD1 1 
ATOM   1205  C CD2 . LEU A 1 312 ? 115.589 120.107 96.065  1.00 52.77  ? 312  LEU A CD2 1 
ATOM   1206  N N   . ALA A 1 313 ? 113.901 118.192 91.407  1.00 54.98  ? 313  ALA A N   1 
ATOM   1207  C CA  . ALA A 1 313 ? 112.746 118.269 90.523  1.00 54.98  ? 313  ALA A CA  1 
ATOM   1208  C C   . ALA A 1 313 ? 111.609 117.410 91.052  1.00 54.98  ? 313  ALA A C   1 
ATOM   1209  O O   . ALA A 1 313 ? 110.569 117.925 91.475  1.00 54.98  ? 313  ALA A O   1 
ATOM   1210  C CB  . ALA A 1 313 ? 113.128 117.829 89.111  1.00 54.98  ? 313  ALA A CB  1 
ATOM   1211  N N   . PHE A 1 314 ? 111.831 116.093 91.105  1.00 54.41  ? 314  PHE A N   1 
ATOM   1212  C CA  . PHE A 1 314 ? 110.746 115.130 91.263  1.00 54.41  ? 314  PHE A CA  1 
ATOM   1213  C C   . PHE A 1 314 ? 110.104 115.172 92.642  1.00 54.41  ? 314  PHE A C   1 
ATOM   1214  O O   . PHE A 1 314 ? 108.966 114.716 92.794  1.00 54.41  ? 314  PHE A O   1 
ATOM   1215  C CB  . PHE A 1 314 ? 111.264 113.725 90.961  1.00 54.41  ? 314  PHE A CB  1 
ATOM   1216  C CG  . PHE A 1 314 ? 111.325 113.410 89.495  1.00 54.41  ? 314  PHE A CG  1 
ATOM   1217  C CD1 . PHE A 1 314 ? 110.169 113.380 88.736  1.00 54.41  ? 314  PHE A CD1 1 
ATOM   1218  C CD2 . PHE A 1 314 ? 112.538 113.152 88.873  1.00 54.41  ? 314  PHE A CD2 1 
ATOM   1219  C CE1 . PHE A 1 314 ? 110.216 113.093 87.384  1.00 54.41  ? 314  PHE A CE1 1 
ATOM   1220  C CE2 . PHE A 1 314 ? 112.596 112.868 87.522  1.00 54.41  ? 314  PHE A CE2 1 
ATOM   1221  C CZ  . PHE A 1 314 ? 111.432 112.836 86.776  1.00 54.41  ? 314  PHE A CZ  1 
ATOM   1222  N N   . MET A 1 315 ? 110.791 115.727 93.639  1.00 54.54  ? 315  MET A N   1 
ATOM   1223  C CA  . MET A 1 315 ? 110.147 115.956 94.925  1.00 54.54  ? 315  MET A CA  1 
ATOM   1224  C C   . MET A 1 315 ? 109.316 117.234 94.897  1.00 54.54  ? 315  MET A C   1 
ATOM   1225  O O   . MET A 1 315 ? 108.190 117.263 95.405  1.00 54.54  ? 315  MET A O   1 
ATOM   1226  C CB  . MET A 1 315 ? 111.193 116.018 96.040  1.00 54.54  ? 315  MET A CB  1 
ATOM   1227  C CG  . MET A 1 315 ? 110.613 115.834 97.438  1.00 54.54  ? 315  MET A CG  1 
ATOM   1228  S SD  . MET A 1 315 ? 111.822 115.987 98.769  1.00 54.54  ? 315  MET A SD  1 
ATOM   1229  C CE  . MET A 1 315 ? 113.055 114.804 98.245  1.00 54.54  ? 315  MET A CE  1 
ATOM   1230  N N   . ASN A 1 316 ? 109.851 118.295 94.293  1.00 57.58  ? 316  ASN A N   1 
ATOM   1231  C CA  . ASN A 1 316 ? 109.260 119.626 94.368  1.00 57.58  ? 316  ASN A CA  1 
ATOM   1232  C C   . ASN A 1 316 ? 108.362 119.951 93.179  1.00 57.58  ? 316  ASN A C   1 
ATOM   1233  O O   . ASN A 1 316 ? 108.004 121.115 92.978  1.00 57.58  ? 316  ASN A O   1 
ATOM   1234  C CB  . ASN A 1 316 ? 110.360 120.675 94.510  1.00 57.58  ? 316  ASN A CB  1 
ATOM   1235  C CG  . ASN A 1 316 ? 111.333 120.348 95.623  1.00 57.58  ? 316  ASN A CG  1 
ATOM   1236  O OD1 . ASN A 1 316 ? 112.048 119.347 95.569  1.00 57.58  ? 316  ASN A OD1 1 
ATOM   1237  N ND2 . ASN A 1 316 ? 111.366 121.195 96.643  1.00 57.58  ? 316  ASN A ND2 1 
ATOM   1238  N N   . ILE A 1 317 ? 107.998 118.955 92.375  1.00 56.62  ? 317  ILE A N   1 
ATOM   1239  C CA  . ILE A 1 317 ? 106.940 119.138 91.387  1.00 56.62  ? 317  ILE A CA  1 
ATOM   1240  C C   . ILE A 1 317 ? 105.585 118.685 91.912  1.00 56.62  ? 317  ILE A C   1 
ATOM   1241  O O   . ILE A 1 317 ? 104.646 118.535 91.116  1.00 56.62  ? 317  ILE A O   1 
ATOM   1242  C CB  . ILE A 1 317 ? 107.255 118.409 90.064  1.00 56.62  ? 317  ILE A CB  1 
ATOM   1243  C CG1 . ILE A 1 317 ? 107.442 116.911 90.309  1.00 56.62  ? 317  ILE A CG1 1 
ATOM   1244  C CG2 . ILE A 1 317 ? 108.425 119.063 89.339  1.00 56.62  ? 317  ILE A CG2 1 
ATOM   1245  C CD1 . ILE A 1 317 ? 107.833 116.141 89.075  1.00 56.62  ? 317  ILE A CD1 1 
ATOM   1246  N N   . LEU A 1 318 ? 105.456 118.452 93.216  1.00 59.98  ? 318  LEU A N   1 
ATOM   1247  C CA  . LEU A 1 318 ? 104.262 117.841 93.776  1.00 59.98  ? 318  LEU A CA  1 
ATOM   1248  C C   . LEU A 1 318 ? 103.738 118.592 94.996  1.00 59.98  ? 318  LEU A C   1 
ATOM   1249  O O   . LEU A 1 318 ? 103.095 117.986 95.858  1.00 59.98  ? 318  LEU A O   1 
ATOM   1250  C CB  . LEU A 1 318 ? 104.550 116.383 94.130  1.00 59.98  ? 318  LEU A CB  1 
ATOM   1251  C CG  . LEU A 1 318 ? 104.321 115.369 93.006  1.00 59.98  ? 318  LEU A CG  1 
ATOM   1252  C CD1 . LEU A 1 318 ? 104.503 113.956 93.522  1.00 59.98  ? 318  LEU A CD1 1 
ATOM   1253  C CD2 . LEU A 1 318 ? 102.965 115.530 92.352  1.00 59.98  ? 318  LEU A CD2 1 
ATOM   1254  N N   . LYS A 1 319 ? 104.016 119.894 95.103  1.00 65.84  ? 319  LYS A N   1 
ATOM   1255  C CA  . LYS A 1 319 ? 103.509 120.662 96.238  1.00 65.84  ? 319  LYS A CA  1 
ATOM   1256  C C   . LYS A 1 319 ? 101.999 120.850 96.150  1.00 65.84  ? 319  LYS A C   1 
ATOM   1257  O O   . LYS A 1 319 ? 101.260 120.498 97.078  1.00 65.84  ? 319  LYS A O   1 
ATOM   1258  C CB  . LYS A 1 319 ? 104.196 122.027 96.330  1.00 65.84  ? 319  LYS A CB  1 
ATOM   1259  C CG  . LYS A 1 319 ? 105.702 122.010 96.475  1.00 65.84  ? 319  LYS A CG  1 
ATOM   1260  C CD  . LYS A 1 319 ? 106.303 123.254 95.842  1.00 65.84  ? 319  LYS A CD  1 
ATOM   1261  C CE  . LYS A 1 319 ? 107.785 123.089 95.590  1.00 65.84  ? 319  LYS A CE  1 
ATOM   1262  N NZ  . LYS A 1 319 ? 108.543 122.838 96.849  1.00 65.84  ? 319  LYS A NZ  1 
ATOM   1263  N N   . LYS A 1 320 ? 101.520 121.406 95.037  1.00 72.24  ? 320  LYS A N   1 
ATOM   1264  C CA  . LYS A 1 320 ? 100.110 121.750 94.909  1.00 72.24  ? 320  LYS A CA  1 
ATOM   1265  C C   . LYS A 1 320 ? 99.231  120.558 94.560  1.00 72.24  ? 320  LYS A C   1 
ATOM   1266  O O   . LYS A 1 320 ? 98.004  120.668 94.657  1.00 72.24  ? 320  LYS A O   1 
ATOM   1267  C CB  . LYS A 1 320 ? 99.933  122.856 93.864  1.00 72.24  ? 320  LYS A CB  1 
ATOM   1268  C CG  . LYS A 1 320 ? 100.942 122.825 92.726  1.00 72.24  ? 320  LYS A CG  1 
ATOM   1269  C CD  . LYS A 1 320 ? 100.616 123.882 91.681  1.00 72.24  ? 320  LYS A CD  1 
ATOM   1270  C CE  . LYS A 1 320 ? 101.107 125.254 92.120  1.00 72.24  ? 320  LYS A CE  1 
ATOM   1271  N NZ  . LYS A 1 320 ? 100.943 126.284 91.058  1.00 72.24  ? 320  LYS A NZ  1 
ATOM   1272  N N   . PHE A 1 321 ? 99.818  119.429 94.164  1.00 66.89  ? 321  PHE A N   1 
ATOM   1273  C CA  . PHE A 1 321 ? 99.022  118.229 93.951  1.00 66.89  ? 321  PHE A CA  1 
ATOM   1274  C C   . PHE A 1 321 ? 98.629  117.557 95.257  1.00 66.89  ? 321  PHE A C   1 
ATOM   1275  O O   . PHE A 1 321 ? 97.615  116.855 95.295  1.00 66.89  ? 321  PHE A O   1 
ATOM   1276  C CB  . PHE A 1 321 ? 99.775  117.240 93.065  1.00 66.89  ? 321  PHE A CB  1 
ATOM   1277  C CG  . PHE A 1 321 ? 98.918  116.124 92.546  1.00 66.89  ? 321  PHE A CG  1 
ATOM   1278  C CD1 . PHE A 1 321 ? 99.147  114.817 92.948  1.00 66.89  ? 321  PHE A CD1 1 
ATOM   1279  C CD2 . PHE A 1 321 ? 97.872  116.383 91.673  1.00 66.89  ? 321  PHE A CD2 1 
ATOM   1280  C CE1 . PHE A 1 321 ? 98.357  113.784 92.477  1.00 66.89  ? 321  PHE A CE1 1 
ATOM   1281  C CE2 . PHE A 1 321 ? 97.076  115.355 91.198  1.00 66.89  ? 321  PHE A CE2 1 
ATOM   1282  C CZ  . PHE A 1 321 ? 97.320  114.054 91.602  1.00 66.89  ? 321  PHE A CZ  1 
ATOM   1283  N N   . ASP A 1 322 ? 99.390  117.768 96.331  1.00 66.98  ? 322  ASP A N   1 
ATOM   1284  C CA  . ASP A 1 322 ? 99.022  117.270 97.649  1.00 66.98  ? 322  ASP A CA  1 
ATOM   1285  C C   . ASP A 1 322 ? 98.130  118.246 98.412  1.00 66.98  ? 322  ASP A C   1 
ATOM   1286  O O   . ASP A 1 322 ? 98.009  118.139 99.637  1.00 66.98  ? 322  ASP A O   1 
ATOM   1287  C CB  . ASP A 1 322 ? 100.274 116.939 98.463  1.00 66.98  ? 322  ASP A CB  1 
ATOM   1288  C CG  . ASP A 1 322 ? 100.954 115.664 97.995  1.00 66.98  ? 322  ASP A CG  1 
ATOM   1289  O OD1 . ASP A 1 322 ? 100.666 114.592 98.568  1.00 66.98  ? 322  ASP A OD1 1 
ATOM   1290  O OD2 . ASP A 1 322 ? 101.767 115.726 97.052  1.00 66.98  ? 322  ASP A OD2 1 
ATOM   1291  N N   . LYS A 1 323 ? 97.517  119.202 97.713  1.00 64.04  ? 323  LYS A N   1 
ATOM   1292  C CA  . LYS A 1 323 ? 96.485  120.057 98.288  1.00 64.04  ? 323  LYS A CA  1 
ATOM   1293  C C   . LYS A 1 323 ? 95.177  119.950 97.517  1.00 64.04  ? 323  LYS A C   1 
ATOM   1294  O O   . LYS A 1 323 ? 94.106  119.938 98.132  1.00 64.04  ? 323  LYS A O   1 
ATOM   1295  C CB  . LYS A 1 323 ? 96.962  121.514 98.344  1.00 64.04  ? 323  LYS A CB  1 
ATOM   1296  C CG  . LYS A 1 323 ? 96.086  122.413 99.206  1.00 64.04  ? 323  LYS A CG  1 
ATOM   1297  C CD  . LYS A 1 323 ? 96.912  123.425 99.979  1.00 64.04  ? 323  LYS A CD  1 
ATOM   1298  C CE  . LYS A 1 323 ? 96.253  123.780 101.303 1.00 64.04  ? 323  LYS A CE  1 
ATOM   1299  N NZ  . LYS A 1 323 ? 97.176  124.539 102.195 1.00 64.04  ? 323  LYS A NZ  1 
ATOM   1300  N N   . VAL A 1 324 ? 95.227  119.874 96.187  1.00 64.18  ? 324  VAL A N   1 
ATOM   1301  C CA  . VAL A 1 324 ? 94.015  119.800 95.378  1.00 64.18  ? 324  VAL A CA  1 
ATOM   1302  C C   . VAL A 1 324 ? 93.499  118.363 95.378  1.00 64.18  ? 324  VAL A C   1 
ATOM   1303  O O   . VAL A 1 324 ? 92.306  118.120 95.162  1.00 64.18  ? 324  VAL A O   1 
ATOM   1304  C CB  . VAL A 1 324 ? 94.261  120.344 93.952  1.00 64.18  ? 324  VAL A CB  1 
ATOM   1305  C CG1 . VAL A 1 324 ? 95.056  119.367 93.083  1.00 64.18  ? 324  VAL A CG1 1 
ATOM   1306  C CG2 . VAL A 1 324 ? 92.946  120.738 93.282  1.00 64.18  ? 324  VAL A CG2 1 
ATOM   1307  N N   . THR A 1 325 ? 94.384  117.400 95.644  1.00 65.07  ? 325  THR A N   1 
ATOM   1308  C CA  . THR A 1 325 ? 93.956  116.017 95.809  1.00 65.07  ? 325  THR A CA  1 
ATOM   1309  C C   . THR A 1 325 ? 94.269  115.484 97.204  1.00 65.07  ? 325  THR A C   1 
ATOM   1310  O O   . THR A 1 325 ? 93.426  114.814 97.810  1.00 65.07  ? 325  THR A O   1 
ATOM   1311  C CB  . THR A 1 325 ? 94.595  115.129 94.737  1.00 65.07  ? 325  THR A CB  1 
ATOM   1312  O OG1 . THR A 1 325 ? 95.968  115.493 94.559  1.00 65.07  ? 325  THR A OG1 1 
ATOM   1313  C CG2 . THR A 1 325 ? 93.863  115.289 93.413  1.00 65.07  ? 325  THR A CG2 1 
ATOM   1314  N N   . GLY A 1 326 ? 95.460  115.777 97.728  1.00 63.22  ? 326  GLY A N   1 
ATOM   1315  C CA  . GLY A 1 326 ? 95.779  115.499 99.118  1.00 63.22  ? 326  GLY A CA  1 
ATOM   1316  C C   . GLY A 1 326 ? 95.933  114.040 99.502  1.00 63.22  ? 326  GLY A C   1 
ATOM   1317  O O   . GLY A 1 326 ? 95.109  113.507 100.251 1.00 63.22  ? 326  GLY A O   1 
ATOM   1318  N N   . LYS A 1 327 ? 96.980  113.380 99.006  1.00 69.97  ? 327  LYS A N   1 
ATOM   1319  C CA  . LYS A 1 327 ? 97.186  111.970 99.316  1.00 69.97  ? 327  LYS A CA  1 
ATOM   1320  C C   . LYS A 1 327 ? 98.575  111.706 99.885  1.00 69.97  ? 327  LYS A C   1 
ATOM   1321  O O   . LYS A 1 327 ? 99.313  112.639 100.214 1.00 69.97  ? 327  LYS A O   1 
ATOM   1322  C CB  . LYS A 1 327 ? 96.969  111.113 98.069  1.00 69.97  ? 327  LYS A CB  1 
ATOM   1323  C CG  . LYS A 1 327 ? 95.540  111.104 97.563  1.00 69.97  ? 327  LYS A CG  1 
ATOM   1324  C CD  . LYS A 1 327 ? 95.414  110.248 96.322  1.00 69.97  ? 327  LYS A CD  1 
ATOM   1325  C CE  . LYS A 1 327 ? 93.978  110.180 95.845  1.00 69.97  ? 327  LYS A CE  1 
ATOM   1326  N NZ  . LYS A 1 327 ? 93.495  111.511 95.389  1.00 69.97  ? 327  LYS A NZ  1 
ATOM   1327  N N   . GLN A 1 328 ? 98.930  110.427 100.011 1.00 66.34  ? 328  GLN A N   1 
ATOM   1328  C CA  . GLN A 1 328 ? 100.251 110.006 100.463 1.00 66.34  ? 328  GLN A CA  1 
ATOM   1329  C C   . GLN A 1 328 ? 101.166 109.639 99.302  1.00 66.34  ? 328  GLN A C   1 
ATOM   1330  O O   . GLN A 1 328 ? 101.998 108.733 99.432  1.00 66.34  ? 328  GLN A O   1 
ATOM   1331  C CB  . GLN A 1 328 ? 100.121 108.828 101.430 1.00 66.34  ? 328  GLN A CB  1 
ATOM   1332  C CG  . GLN A 1 328 ? 99.445  109.168 102.749 1.00 66.34  ? 328  GLN A CG  1 
ATOM   1333  C CD  . GLN A 1 328 ? 100.438 109.436 103.864 1.00 66.34  ? 328  GLN A CD  1 
ATOM   1334  O OE1 . GLN A 1 328 ? 101.258 110.350 103.774 1.00 66.34  ? 328  GLN A OE1 1 
ATOM   1335  N NE2 . GLN A 1 328 ? 100.373 108.633 104.921 1.00 66.34  ? 328  GLN A NE2 1 
ATOM   1336  N N   . ILE A 1 329 ? 101.029 110.325 98.164  1.00 65.36  ? 329  ILE A N   1 
ATOM   1337  C CA  . ILE A 1 329 ? 101.729 109.927 96.945  1.00 65.36  ? 329  ILE A CA  1 
ATOM   1338  C C   . ILE A 1 329 ? 103.167 110.419 96.902  1.00 65.36  ? 329  ILE A C   1 
ATOM   1339  O O   . ILE A 1 329 ? 103.973 109.868 96.142  1.00 65.36  ? 329  ILE A O   1 
ATOM   1340  C CB  . ILE A 1 329 ? 100.909 110.409 95.728  1.00 65.36  ? 329  ILE A CB  1 
ATOM   1341  C CG1 . ILE A 1 329 ? 101.211 109.574 94.479  1.00 65.36  ? 329  ILE A CG1 1 
ATOM   1342  C CG2 . ILE A 1 329 ? 101.128 111.896 95.457  1.00 65.36  ? 329  ILE A CG2 1 
ATOM   1343  C CD1 . ILE A 1 329 ? 100.944 108.103 94.652  1.00 65.36  ? 329  ILE A CD1 1 
ATOM   1344  N N   . LEU A 1 330 ? 103.523 111.419 97.712  1.00 63.20  ? 330  LEU A N   1 
ATOM   1345  C CA  . LEU A 1 330 ? 104.875 111.974 97.646  1.00 63.20  ? 330  LEU A CA  1 
ATOM   1346  C C   . LEU A 1 330 ? 105.991 111.037 98.122  1.00 63.20  ? 330  LEU A C   1 
ATOM   1347  O O   . LEU A 1 330 ? 107.128 111.221 97.650  1.00 63.20  ? 330  LEU A O   1 
ATOM   1348  C CB  . LEU A 1 330 ? 104.925 113.333 98.369  1.00 63.20  ? 330  LEU A CB  1 
ATOM   1349  C CG  . LEU A 1 330 ? 104.616 113.622 99.839  1.00 63.20  ? 330  LEU A CG  1 
ATOM   1350  C CD1 . LEU A 1 330 ? 105.899 113.630 100.655 1.00 63.20  ? 330  LEU A CD1 1 
ATOM   1351  C CD2 . LEU A 1 330 ? 103.875 114.938 99.986  1.00 63.20  ? 330  LEU A CD2 1 
ATOM   1352  N N   . PRO A 1 331 ? 105.789 110.056 99.013  1.00 62.10  ? 331  PRO A N   1 
ATOM   1353  C CA  . PRO A 1 331 ? 106.766 108.962 99.088  1.00 62.10  ? 331  PRO A CA  1 
ATOM   1354  C C   . PRO A 1 331 ? 106.454 107.757 98.214  1.00 62.10  ? 331  PRO A C   1 
ATOM   1355  O O   . PRO A 1 331 ? 107.369 106.965 97.955  1.00 62.10  ? 331  PRO A O   1 
ATOM   1356  C CB  . PRO A 1 331 ? 106.728 108.573 100.571 1.00 62.10  ? 331  PRO A CB  1 
ATOM   1357  C CG  . PRO A 1 331 ? 105.345 108.793 100.943 1.00 62.10  ? 331  PRO A CG  1 
ATOM   1358  C CD  . PRO A 1 331 ? 104.951 110.052 100.235 1.00 62.10  ? 331  PRO A CD  1 
ATOM   1359  N N   . ILE A 1 332 ? 105.209 107.586 97.759  1.00 61.47  ? 332  ILE A N   1 
ATOM   1360  C CA  . ILE A 1 332 ? 104.869 106.418 96.950  1.00 61.47  ? 332  ILE A CA  1 
ATOM   1361  C C   . ILE A 1 332 ? 105.435 106.566 95.545  1.00 61.47  ? 332  ILE A C   1 
ATOM   1362  O O   . ILE A 1 332 ? 106.092 105.657 95.021  1.00 61.47  ? 332  ILE A O   1 
ATOM   1363  C CB  . ILE A 1 332 ? 103.345 106.201 96.930  1.00 61.47  ? 332  ILE A CB  1 
ATOM   1364  C CG1 . ILE A 1 332 ? 102.857 105.733 98.302  1.00 61.47  ? 332  ILE A CG1 1 
ATOM   1365  C CG2 . ILE A 1 332 ? 102.950 105.180 95.868  1.00 61.47  ? 332  ILE A CG2 1 
ATOM   1366  C CD1 . ILE A 1 332 ? 103.547 104.485 98.808  1.00 61.47  ? 332  ILE A CD1 1 
ATOM   1367  N N   . TYR A 1 333 ? 105.189 107.719 94.917  1.00 59.85  ? 333  TYR A N   1 
ATOM   1368  C CA  . TYR A 1 333 ? 105.821 108.057 93.648  1.00 59.85  ? 333  TYR A CA  1 
ATOM   1369  C C   . TYR A 1 333 ? 107.338 108.126 93.767  1.00 59.85  ? 333  TYR A C   1 
ATOM   1370  O O   . TYR A 1 333 ? 108.034 107.781 92.812  1.00 59.85  ? 333  TYR A O   1 
ATOM   1371  C CB  . TYR A 1 333 ? 105.280 109.400 93.147  1.00 59.85  ? 333  TYR A CB  1 
ATOM   1372  C CG  . TYR A 1 333 ? 105.901 109.936 91.871  1.00 59.85  ? 333  TYR A CG  1 
ATOM   1373  C CD1 . TYR A 1 333 ? 106.130 109.115 90.768  1.00 59.85  ? 333  TYR A CD1 1 
ATOM   1374  C CD2 . TYR A 1 333 ? 106.286 111.268 91.785  1.00 59.85  ? 333  TYR A CD2 1 
ATOM   1375  C CE1 . TYR A 1 333 ? 106.713 109.612 89.620  1.00 59.85  ? 333  TYR A CE1 1 
ATOM   1376  C CE2 . TYR A 1 333 ? 106.863 111.775 90.639  1.00 59.85  ? 333  TYR A CE2 1 
ATOM   1377  C CZ  . TYR A 1 333 ? 107.073 110.943 89.562  1.00 59.85  ? 333  TYR A CZ  1 
ATOM   1378  O OH  . TYR A 1 333 ? 107.648 111.451 88.424  1.00 59.85  ? 333  TYR A OH  1 
ATOM   1379  N N   . LEU A 1 334 ? 107.866 108.525 94.926  1.00 54.58  ? 334  LEU A N   1 
ATOM   1380  C CA  . LEU A 1 334 ? 109.303 108.727 95.058  1.00 54.58  ? 334  LEU A CA  1 
ATOM   1381  C C   . LEU A 1 334 ? 110.080 107.414 95.018  1.00 54.58  ? 334  LEU A C   1 
ATOM   1382  O O   . LEU A 1 334 ? 111.265 107.419 94.670  1.00 54.58  ? 334  LEU A O   1 
ATOM   1383  C CB  . LEU A 1 334 ? 109.591 109.490 96.354  1.00 54.58  ? 334  LEU A CB  1 
ATOM   1384  C CG  . LEU A 1 334 ? 110.974 110.090 96.607  1.00 54.58  ? 334  LEU A CG  1 
ATOM   1385  C CD1 . LEU A 1 334 ? 111.458 110.794 95.360  1.00 54.58  ? 334  LEU A CD1 1 
ATOM   1386  C CD2 . LEU A 1 334 ? 110.938 111.059 97.775  1.00 54.58  ? 334  LEU A CD2 1 
ATOM   1387  N N   . LYS A 1 335 ? 109.434 106.287 95.314  1.00 50.23  ? 335  LYS A N   1 
ATOM   1388  C CA  . LYS A 1 335 ? 110.130 105.008 95.328  1.00 50.23  ? 335  LYS A CA  1 
ATOM   1389  C C   . LYS A 1 335 ? 110.162 104.307 93.974  1.00 50.23  ? 335  LYS A C   1 
ATOM   1390  O O   . LYS A 1 335 ? 110.659 103.181 93.901  1.00 50.23  ? 335  LYS A O   1 
ATOM   1391  C CB  . LYS A 1 335 ? 109.520 104.084 96.384  1.00 50.23  ? 335  LYS A CB  1 
ATOM   1392  C CG  . LYS A 1 335 ? 109.631 104.582 97.834  1.00 50.23  ? 335  LYS A CG  1 
ATOM   1393  C CD  . LYS A 1 335 ? 111.061 104.552 98.398  1.00 50.23  ? 335  LYS A CD  1 
ATOM   1394  C CE  . LYS A 1 335 ? 111.708 105.940 98.459  1.00 50.23  ? 335  LYS A CE  1 
ATOM   1395  N NZ  . LYS A 1 335 ? 113.059 105.918 99.079  1.00 50.23  ? 335  LYS A NZ  1 
ATOM   1396  N N   . VAL A 1 336 ? 109.634 104.914 92.908  1.00 57.33  ? 336  VAL A N   1 
ATOM   1397  C CA  . VAL A 1 336 ? 110.081 104.559 91.566  1.00 57.33  ? 336  VAL A CA  1 
ATOM   1398  C C   . VAL A 1 336 ? 111.044 105.592 91.017  1.00 57.33  ? 336  VAL A C   1 
ATOM   1399  O O   . VAL A 1 336 ? 111.649 105.372 89.960  1.00 57.33  ? 336  VAL A O   1 
ATOM   1400  C CB  . VAL A 1 336 ? 108.910 104.334 90.585  1.00 57.33  ? 336  VAL A CB  1 
ATOM   1401  C CG1 . VAL A 1 336 ? 108.118 103.106 90.983  1.00 57.33  ? 336  VAL A CG1 1 
ATOM   1402  C CG2 . VAL A 1 336 ? 108.021 105.545 90.481  1.00 57.33  ? 336  VAL A CG2 1 
ATOM   1403  N N   . VAL A 1 337 ? 111.220 106.705 91.722  1.00 54.82  ? 337  VAL A N   1 
ATOM   1404  C CA  . VAL A 1 337 ? 112.250 107.686 91.415  1.00 54.82  ? 337  VAL A CA  1 
ATOM   1405  C C   . VAL A 1 337 ? 113.572 107.322 92.071  1.00 54.82  ? 337  VAL A C   1 
ATOM   1406  O O   . VAL A 1 337 ? 114.614 107.307 91.418  1.00 54.82  ? 337  VAL A O   1 
ATOM   1407  C CB  . VAL A 1 337 ? 111.790 109.100 91.833  1.00 54.82  ? 337  VAL A CB  1 
ATOM   1408  C CG1 . VAL A 1 337 ? 112.779 110.142 91.342  1.00 54.82  ? 337  VAL A CG1 1 
ATOM   1409  C CG2 . VAL A 1 337 ? 110.419 109.389 91.267  1.00 54.82  ? 337  VAL A CG2 1 
ATOM   1410  N N   . GLU A 1 338 ? 113.549 107.023 93.370  1.00 48.37  ? 338  GLU A N   1 
ATOM   1411  C CA  . GLU A 1 338 ? 114.784 106.680 94.057  1.00 48.37  ? 338  GLU A CA  1 
ATOM   1412  C C   . GLU A 1 338 ? 115.265 105.280 93.698  1.00 48.37  ? 338  GLU A C   1 
ATOM   1413  O O   . GLU A 1 338 ? 116.474 105.028 93.731  1.00 48.37  ? 338  GLU A O   1 
ATOM   1414  C CB  . GLU A 1 338 ? 114.591 106.789 95.568  1.00 48.37  ? 338  GLU A CB  1 
ATOM   1415  C CG  . GLU A 1 338 ? 114.122 108.150 96.071  1.00 48.37  ? 338  GLU A CG  1 
ATOM   1416  C CD  . GLU A 1 338 ? 115.125 109.260 95.879  1.00 48.37  ? 338  GLU A CD  1 
ATOM   1417  O OE1 . GLU A 1 338 ? 116.333 108.978 95.857  1.00 48.37  ? 338  GLU A OE1 1 
ATOM   1418  O OE2 . GLU A 1 338 ? 114.709 110.429 95.788  1.00 48.37  ? 338  GLU A OE2 1 
ATOM   1419  N N   . SER A 1 339 ? 114.351 104.371 93.349  1.00 54.39  ? 339  SER A N   1 
ATOM   1420  C CA  . SER A 1 339 ? 114.723 103.045 92.871  1.00 54.39  ? 339  SER A CA  1 
ATOM   1421  C C   . SER A 1 339 ? 115.057 103.016 91.390  1.00 54.39  ? 339  SER A C   1 
ATOM   1422  O O   . SER A 1 339 ? 115.445 101.960 90.882  1.00 54.39  ? 339  SER A O   1 
ATOM   1423  C CB  . SER A 1 339 ? 113.608 102.032 93.123  1.00 54.39  ? 339  SER A CB  1 
ATOM   1424  O OG  . SER A 1 339 ? 112.394 102.472 92.554  1.00 54.39  ? 339  SER A OG  1 
ATOM   1425  N N   . SER A 1 340 ? 114.891 104.126 90.680  1.00 55.87  ? 340  SER A N   1 
ATOM   1426  C CA  . SER A 1 340 ? 115.374 104.161 89.316  1.00 55.87  ? 340  SER A CA  1 
ATOM   1427  C C   . SER A 1 340 ? 116.893 104.256 89.319  1.00 55.87  ? 340  SER A C   1 
ATOM   1428  O O   . SER A 1 340 ? 117.515 104.561 90.339  1.00 55.87  ? 340  SER A O   1 
ATOM   1429  C CB  . SER A 1 340 ? 114.765 105.325 88.553  1.00 55.87  ? 340  SER A CB  1 
ATOM   1430  O OG  . SER A 1 340 ? 114.830 105.065 87.166  1.00 55.87  ? 340  SER A OG  1 
ATOM   1431  N N   . TYR A 1 341 ? 117.477 104.028 88.137  1.00 53.80  ? 341  TYR A N   1 
ATOM   1432  C CA  . TYR A 1 341 ? 118.901 103.712 88.025  1.00 53.80  ? 341  TYR A CA  1 
ATOM   1433  C C   . TYR A 1 341 ? 119.791 104.867 88.474  1.00 53.80  ? 341  TYR A C   1 
ATOM   1434  O O   . TYR A 1 341 ? 120.926 104.648 88.914  1.00 53.80  ? 341  TYR A O   1 
ATOM   1435  C CB  . TYR A 1 341 ? 119.225 103.305 86.584  1.00 53.80  ? 341  TYR A CB  1 
ATOM   1436  C CG  . TYR A 1 341 ? 120.681 102.993 86.346  1.00 53.80  ? 341  TYR A CG  1 
ATOM   1437  C CD1 . TYR A 1 341 ? 121.537 103.945 85.804  1.00 53.80  ? 341  TYR A CD1 1 
ATOM   1438  C CD2 . TYR A 1 341 ? 121.204 101.755 86.678  1.00 53.80  ? 341  TYR A CD2 1 
ATOM   1439  C CE1 . TYR A 1 341 ? 122.870 103.675 85.608  1.00 53.80  ? 341  TYR A CE1 1 
ATOM   1440  C CE2 . TYR A 1 341 ? 122.541 101.470 86.472  1.00 53.80  ? 341  TYR A CE2 1 
ATOM   1441  C CZ  . TYR A 1 341 ? 123.367 102.436 85.933  1.00 53.80  ? 341  TYR A CZ  1 
ATOM   1442  O OH  . TYR A 1 341 ? 124.697 102.160 85.727  1.00 53.80  ? 341  TYR A OH  1 
ATOM   1443  N N   . PHE A 1 342 ? 119.289 106.100 88.400  1.00 56.08  ? 342  PHE A N   1 
ATOM   1444  C CA  . PHE A 1 342 ? 120.136 107.237 88.732  1.00 56.08  ? 342  PHE A CA  1 
ATOM   1445  C C   . PHE A 1 342 ? 120.292 107.443 90.234  1.00 56.08  ? 342  PHE A C   1 
ATOM   1446  O O   . PHE A 1 342 ? 121.218 108.146 90.649  1.00 56.08  ? 342  PHE A O   1 
ATOM   1447  C CB  . PHE A 1 342 ? 119.633 108.517 88.045  1.00 56.08  ? 342  PHE A CB  1 
ATOM   1448  C CG  . PHE A 1 342 ? 118.313 109.022 88.535  1.00 56.08  ? 342  PHE A CG  1 
ATOM   1449  C CD1 . PHE A 1 342 ? 117.124 108.481 88.077  1.00 56.08  ? 342  PHE A CD1 1 
ATOM   1450  C CD2 . PHE A 1 342 ? 118.263 110.089 89.413  1.00 56.08  ? 342  PHE A CD2 1 
ATOM   1451  C CE1 . PHE A 1 342 ? 115.911 108.966 88.518  1.00 56.08  ? 342  PHE A CE1 1 
ATOM   1452  C CE2 . PHE A 1 342 ? 117.058 110.577 89.852  1.00 56.08  ? 342  PHE A CE2 1 
ATOM   1453  C CZ  . PHE A 1 342 ? 115.878 110.017 89.409  1.00 56.08  ? 342  PHE A CZ  1 
ATOM   1454  N N   . ASN A 1 343 ? 119.436 106.837 91.059  1.00 47.18  ? 343  ASN A N   1 
ATOM   1455  C CA  . ASN A 1 343 ? 119.663 106.844 92.496  1.00 47.18  ? 343  ASN A CA  1 
ATOM   1456  C C   . ASN A 1 343 ? 119.785 105.468 93.131  1.00 47.18  ? 343  ASN A C   1 
ATOM   1457  O O   . ASN A 1 343 ? 120.386 105.367 94.204  1.00 47.18  ? 343  ASN A O   1 
ATOM   1458  C CB  . ASN A 1 343 ? 118.554 107.600 93.233  1.00 47.18  ? 343  ASN A CB  1 
ATOM   1459  C CG  . ASN A 1 343 ? 119.049 108.205 94.517  1.00 47.18  ? 343  ASN A CG  1 
ATOM   1460  O OD1 . ASN A 1 343 ? 120.080 108.873 94.547  1.00 47.18  ? 343  ASN A OD1 1 
ATOM   1461  N ND2 . ASN A 1 343 ? 118.361 107.911 95.604  1.00 47.18  ? 343  ASN A ND2 1 
ATOM   1462  N N   . ILE A 1 344 ? 119.252 104.409 92.513  1.00 48.11  ? 344  ILE A N   1 
ATOM   1463  C CA  . ILE A 1 344 ? 119.390 103.081 93.103  1.00 48.11  ? 344  ILE A CA  1 
ATOM   1464  C C   . ILE A 1 344 ? 120.821 102.578 92.917  1.00 48.11  ? 344  ILE A C   1 
ATOM   1465  O O   . ILE A 1 344 ? 121.252 101.630 93.582  1.00 48.11  ? 344  ILE A O   1 
ATOM   1466  C CB  . ILE A 1 344 ? 118.345 102.118 92.507  1.00 48.11  ? 344  ILE A CB  1 
ATOM   1467  C CG1 . ILE A 1 344 ? 118.161 100.882 93.388  1.00 48.11  ? 344  ILE A CG1 1 
ATOM   1468  C CG2 . ILE A 1 344 ? 118.781 101.631 91.145  1.00 48.11  ? 344  ILE A CG2 1 
ATOM   1469  C CD1 . ILE A 1 344 ? 117.051 99.956  92.937  1.00 48.11  ? 344  ILE A CD1 1 
ATOM   1470  N N   . SER A 1 345 ? 121.586 103.208 92.035  1.00 46.43  ? 345  SER A N   1 
ATOM   1471  C CA  . SER A 1 345 ? 123.021 103.016 91.984  1.00 46.43  ? 345  SER A CA  1 
ATOM   1472  C C   . SER A 1 345 ? 123.731 104.227 92.565  1.00 46.43  ? 345  SER A C   1 
ATOM   1473  O O   . SER A 1 345 ? 123.123 105.272 92.805  1.00 46.43  ? 345  SER A O   1 
ATOM   1474  C CB  . SER A 1 345 ? 123.500 102.796 90.554  1.00 46.43  ? 345  SER A CB  1 
ATOM   1475  O OG  . SER A 1 345 ? 124.913 102.755 90.523  1.00 46.43  ? 345  SER A OG  1 
ATOM   1476  N N   . ASP A 1 346 ? 125.027 104.056 92.809  1.00 46.64  ? 346  ASP A N   1 
ATOM   1477  C CA  . ASP A 1 346 ? 125.995 105.124 93.031  1.00 46.64  ? 346  ASP A CA  1 
ATOM   1478  C C   . ASP A 1 346 ? 127.258 104.837 92.237  1.00 46.64  ? 346  ASP A C   1 
ATOM   1479  O O   . ASP A 1 346 ? 128.375 104.967 92.742  1.00 46.64  ? 346  ASP A O   1 
ATOM   1480  C CB  . ASP A 1 346 ? 126.327 105.307 94.514  1.00 46.64  ? 346  ASP A CB  1 
ATOM   1481  C CG  . ASP A 1 346 ? 125.270 106.106 95.277  1.00 46.64  ? 346  ASP A CG  1 
ATOM   1482  O OD1 . ASP A 1 346 ? 124.618 106.977 94.673  1.00 46.64  ? 346  ASP A OD1 1 
ATOM   1483  O OD2 . ASP A 1 346 ? 125.108 105.879 96.494  1.00 46.64  ? 346  ASP A OD2 1 
ATOM   1484  N N   . LYS A 1 347 ? 127.096 104.426 90.977  1.00 53.85  ? 347  LYS A N   1 
ATOM   1485  C CA  . LYS A 1 347 ? 128.255 104.102 90.150  1.00 53.85  ? 347  LYS A CA  1 
ATOM   1486  C C   . LYS A 1 347 ? 129.028 105.344 89.726  1.00 53.85  ? 347  LYS A C   1 
ATOM   1487  O O   . LYS A 1 347 ? 130.164 105.227 89.262  1.00 53.85  ? 347  LYS A O   1 
ATOM   1488  C CB  . LYS A 1 347 ? 127.835 103.308 88.913  1.00 53.85  ? 347  LYS A CB  1 
ATOM   1489  C CG  . LYS A 1 347 ? 127.728 101.807 89.128  1.00 53.85  ? 347  LYS A CG  1 
ATOM   1490  C CD  . LYS A 1 347 ? 128.027 101.019 87.858  1.00 53.85  ? 347  LYS A CD  1 
ATOM   1491  C CE  . LYS A 1 347 ? 129.353 101.422 87.233  1.00 53.85  ? 347  LYS A CE  1 
ATOM   1492  N NZ  . LYS A 1 347 ? 129.889 100.352 86.346  1.00 53.85  ? 347  LYS A NZ  1 
ATOM   1493  N N   . VAL A 1 348 ? 128.427 106.532 89.821  1.00 58.80  ? 348  VAL A N   1 
ATOM   1494  C CA  . VAL A 1 348 ? 129.220 107.743 89.654  1.00 58.80  ? 348  VAL A CA  1 
ATOM   1495  C C   . VAL A 1 348 ? 130.013 108.048 90.918  1.00 58.80  ? 348  VAL A C   1 
ATOM   1496  O O   . VAL A 1 348 ? 131.045 108.723 90.851  1.00 58.80  ? 348  VAL A O   1 
ATOM   1497  C CB  . VAL A 1 348 ? 128.329 108.933 89.232  1.00 58.80  ? 348  VAL A CB  1 
ATOM   1498  C CG1 . VAL A 1 348 ? 127.550 108.581 87.982  1.00 58.80  ? 348  VAL A CG1 1 
ATOM   1499  C CG2 . VAL A 1 348 ? 127.372 109.339 90.342  1.00 58.80  ? 348  VAL A CG2 1 
ATOM   1500  N N   . MET A 1 349 ? 129.576 107.530 92.070  1.00 58.57  ? 349  MET A N   1 
ATOM   1501  C CA  . MET A 1 349 ? 130.209 107.829 93.346  1.00 58.57  ? 349  MET A CA  1 
ATOM   1502  C C   . MET A 1 349 ? 131.381 106.915 93.662  1.00 58.57  ? 349  MET A C   1 
ATOM   1503  O O   . MET A 1 349 ? 132.221 107.276 94.493  1.00 58.57  ? 349  MET A O   1 
ATOM   1504  C CB  . MET A 1 349 ? 129.179 107.749 94.477  1.00 58.57  ? 349  MET A CB  1 
ATOM   1505  C CG  . MET A 1 349 ? 128.318 108.991 94.610  1.00 58.57  ? 349  MET A CG  1 
ATOM   1506  S SD  . MET A 1 349 ? 129.174 110.309 95.494  1.00 58.57  ? 349  MET A SD  1 
ATOM   1507  C CE  . MET A 1 349 ? 127.831 111.452 95.801  1.00 58.57  ? 349  MET A CE  1 
ATOM   1508  N N   . ILE A 1 350 ? 131.464 105.741 93.033  1.00 57.82  ? 350  ILE A N   1 
ATOM   1509  C CA  . ILE A 1 350 ? 132.676 104.936 93.151  1.00 57.82  ? 350  ILE A CA  1 
ATOM   1510  C C   . ILE A 1 350 ? 133.798 105.586 92.344  1.00 57.82  ? 350  ILE A C   1 
ATOM   1511  O O   . ILE A 1 350 ? 134.985 105.459 92.669  1.00 57.82  ? 350  ILE A O   1 
ATOM   1512  C CB  . ILE A 1 350 ? 132.394 103.476 92.729  1.00 57.82  ? 350  ILE A CB  1 
ATOM   1513  C CG1 . ILE A 1 350 ? 133.623 102.575 92.893  1.00 57.82  ? 350  ILE A CG1 1 
ATOM   1514  C CG2 . ILE A 1 350 ? 131.874 103.390 91.315  1.00 57.82  ? 350  ILE A CG2 1 
ATOM   1515  C CD1 . ILE A 1 350 ? 133.345 101.112 92.622  1.00 57.82  ? 350  ILE A CD1 1 
ATOM   1516  N N   . LEU A 1 351 ? 133.429 106.364 91.327  1.00 57.69  ? 351  LEU A N   1 
ATOM   1517  C CA  . LEU A 1 351 ? 134.378 107.204 90.613  1.00 57.69  ? 351  LEU A CA  1 
ATOM   1518  C C   . LEU A 1 351 ? 134.776 108.447 91.395  1.00 57.69  ? 351  LEU A C   1 
ATOM   1519  O O   . LEU A 1 351 ? 135.778 109.076 91.046  1.00 57.69  ? 351  LEU A O   1 
ATOM   1520  C CB  . LEU A 1 351 ? 133.802 107.614 89.259  1.00 57.69  ? 351  LEU A CB  1 
ATOM   1521  C CG  . LEU A 1 351 ? 133.076 106.504 88.506  1.00 57.69  ? 351  LEU A CG  1 
ATOM   1522  C CD1 . LEU A 1 351 ? 132.264 107.070 87.359  1.00 57.69  ? 351  LEU A CD1 1 
ATOM   1523  C CD2 . LEU A 1 351 ? 134.062 105.471 88.006  1.00 57.69  ? 351  LEU A CD2 1 
ATOM   1524  N N   . SER A 1 352 ? 134.031 108.806 92.444  1.00 62.73  ? 352  SER A N   1 
ATOM   1525  C CA  . SER A 1 352 ? 134.332 110.024 93.192  1.00 62.73  ? 352  SER A CA  1 
ATOM   1526  C C   . SER A 1 352 ? 135.594 109.867 94.029  1.00 62.73  ? 352  SER A C   1 
ATOM   1527  O O   . SER A 1 352 ? 136.261 110.858 94.347  1.00 62.73  ? 352  SER A O   1 
ATOM   1528  C CB  . SER A 1 352 ? 133.149 110.404 94.078  1.00 62.73  ? 352  SER A CB  1 
ATOM   1529  O OG  . SER A 1 352 ? 133.065 109.548 95.203  1.00 62.73  ? 352  SER A OG  1 
ATOM   1530  N N   . ASP A 1 353 ? 135.932 108.638 94.408  1.00 57.01  ? 353  ASP A N   1 
ATOM   1531  C CA  . ASP A 1 353 ? 137.212 108.361 95.043  1.00 57.01  ? 353  ASP A CA  1 
ATOM   1532  C C   . ASP A 1 353 ? 138.216 107.749 94.077  1.00 57.01  ? 353  ASP A C   1 
ATOM   1533  O O   . ASP A 1 353 ? 139.418 107.754 94.365  1.00 57.01  ? 353  ASP A O   1 
ATOM   1534  C CB  . ASP A 1 353 ? 137.019 107.438 96.249  1.00 57.01  ? 353  ASP A CB  1 
ATOM   1535  C CG  . ASP A 1 353 ? 138.138 107.567 97.264  1.00 57.01  ? 353  ASP A CG  1 
ATOM   1536  O OD1 . ASP A 1 353 ? 138.345 106.619 98.051  1.00 57.01  ? 353  ASP A OD1 1 
ATOM   1537  O OD2 . ASP A 1 353 ? 138.815 108.617 97.270  1.00 57.01  ? 353  ASP A OD2 1 
ATOM   1538  N N   . GLU A 1 354 ? 137.750 107.232 92.940  1.00 59.37  ? 354  GLU A N   1 
ATOM   1539  C CA  . GLU A 1 354 ? 138.634 106.729 91.899  1.00 59.37  ? 354  GLU A CA  1 
ATOM   1540  C C   . GLU A 1 354 ? 139.433 107.843 91.232  1.00 59.37  ? 354  GLU A C   1 
ATOM   1541  O O   . GLU A 1 354 ? 140.575 107.612 90.827  1.00 59.37  ? 354  GLU A O   1 
ATOM   1542  C CB  . GLU A 1 354 ? 137.800 105.950 90.871  1.00 59.37  ? 354  GLU A CB  1 
ATOM   1543  C CG  . GLU A 1 354 ? 138.494 105.504 89.591  1.00 59.37  ? 354  GLU A CG  1 
ATOM   1544  C CD  . GLU A 1 354 ? 138.298 106.480 88.444  1.00 59.37  ? 354  GLU A CD  1 
ATOM   1545  O OE1 . GLU A 1 354 ? 137.134 106.785 88.112  1.00 59.37  ? 354  GLU A OE1 1 
ATOM   1546  O OE2 . GLU A 1 354 ? 139.309 106.949 87.884  1.00 59.37  ? 354  GLU A OE2 1 
ATOM   1547  N N   . VAL A 1 355 ? 138.877 109.052 91.144  1.00 61.04  ? 355  VAL A N   1 
ATOM   1548  C CA  . VAL A 1 355 ? 139.586 110.159 90.508  1.00 61.04  ? 355  VAL A CA  1 
ATOM   1549  C C   . VAL A 1 355 ? 140.807 110.621 91.295  1.00 61.04  ? 355  VAL A C   1 
ATOM   1550  O O   . VAL A 1 355 ? 141.708 111.237 90.714  1.00 61.04  ? 355  VAL A O   1 
ATOM   1551  C CB  . VAL A 1 355 ? 138.634 111.341 90.279  1.00 61.04  ? 355  VAL A CB  1 
ATOM   1552  C CG1 . VAL A 1 355 ? 137.642 111.008 89.182  1.00 61.04  ? 355  VAL A CG1 1 
ATOM   1553  C CG2 . VAL A 1 355 ? 137.903 111.669 91.569  1.00 61.04  ? 355  VAL A CG2 1 
ATOM   1554  N N   . GLU A 1 356 ? 140.872 110.335 92.590  1.00 61.39  ? 356  GLU A N   1 
ATOM   1555  C CA  . GLU A 1 356 ? 142.017 110.705 93.405  1.00 61.39  ? 356  GLU A CA  1 
ATOM   1556  C C   . GLU A 1 356 ? 142.865 109.511 93.814  1.00 61.39  ? 356  GLU A C   1 
ATOM   1557  O O   . GLU A 1 356 ? 143.331 109.473 94.954  1.00 61.39  ? 356  GLU A O   1 
ATOM   1558  C CB  . GLU A 1 356 ? 141.561 111.447 94.662  1.00 61.39  ? 356  GLU A CB  1 
ATOM   1559  C CG  . GLU A 1 356 ? 140.960 112.813 94.413  1.00 61.39  ? 356  GLU A CG  1 
ATOM   1560  C CD  . GLU A 1 356 ? 140.504 113.482 95.695  1.00 61.39  ? 356  GLU A CD  1 
ATOM   1561  O OE1 . GLU A 1 356 ? 140.543 112.828 96.757  1.00 61.39  ? 356  GLU A OE1 1 
ATOM   1562  O OE2 . GLU A 1 356 ? 140.104 114.662 95.645  1.00 61.39  ? 356  GLU A OE2 1 
ATOM   1563  N N   . GLU A 1 357 ? 143.056 108.522 92.937  1.00 65.82  ? 357  GLU A N   1 
ATOM   1564  C CA  . GLU A 1 357 ? 143.939 107.421 93.310  1.00 65.82  ? 357  GLU A CA  1 
ATOM   1565  C C   . GLU A 1 357 ? 145.393 107.747 92.986  1.00 65.82  ? 357  GLU A C   1 
ATOM   1566  O O   . GLU A 1 357 ? 146.299 107.375 93.740  1.00 65.82  ? 357  GLU A O   1 
ATOM   1567  C CB  . GLU A 1 357 ? 143.504 106.111 92.643  1.00 65.82  ? 357  GLU A CB  1 
ATOM   1568  C CG  . GLU A 1 357 ? 143.420 106.107 91.130  1.00 65.82  ? 357  GLU A CG  1 
ATOM   1569  C CD  . GLU A 1 357 ? 142.483 105.034 90.606  1.00 65.82  ? 357  GLU A CD  1 
ATOM   1570  O OE1 . GLU A 1 357 ? 141.764 105.297 89.622  1.00 65.82  ? 357  GLU A OE1 1 
ATOM   1571  O OE2 . GLU A 1 357 ? 142.454 103.931 91.190  1.00 65.82  ? 357  GLU A OE2 1 
ATOM   1572  N N   . TRP A 1 358 ? 145.641 108.446 91.879  1.00 66.52  ? 358  TRP A N   1 
ATOM   1573  C CA  . TRP A 1 358 ? 146.984 108.904 91.557  1.00 66.52  ? 358  TRP A CA  1 
ATOM   1574  C C   . TRP A 1 358 ? 147.119 110.413 91.628  1.00 66.52  ? 358  TRP A C   1 
ATOM   1575  O O   . TRP A 1 358 ? 148.235 110.929 91.504  1.00 66.52  ? 358  TRP A O   1 
ATOM   1576  C CB  . TRP A 1 358 ? 147.399 108.436 90.156  1.00 66.52  ? 358  TRP A CB  1 
ATOM   1577  C CG  . TRP A 1 358 ? 146.831 107.113 89.735  1.00 66.52  ? 358  TRP A CG  1 
ATOM   1578  C CD1 . TRP A 1 358 ? 146.031 106.881 88.657  1.00 66.52  ? 358  TRP A CD1 1 
ATOM   1579  C CD2 . TRP A 1 358 ? 147.033 105.839 90.365  1.00 66.52  ? 358  TRP A CD2 1 
ATOM   1580  N NE1 . TRP A 1 358 ? 145.713 105.548 88.580  1.00 66.52  ? 358  TRP A NE1 1 
ATOM   1581  C CE2 . TRP A 1 358 ? 146.318 104.886 89.615  1.00 66.52  ? 358  TRP A CE2 1 
ATOM   1582  C CE3 . TRP A 1 358 ? 147.747 105.413 91.491  1.00 66.52  ? 358  TRP A CE3 1 
ATOM   1583  C CZ2 . TRP A 1 358 ? 146.289 103.536 89.956  1.00 66.52  ? 358  TRP A CZ2 1 
ATOM   1584  C CZ3 . TRP A 1 358 ? 147.717 104.072 91.827  1.00 66.52  ? 358  TRP A CZ3 1 
ATOM   1585  C CH2 . TRP A 1 358 ? 146.995 103.150 91.061  1.00 66.52  ? 358  TRP A CH2 1 
ATOM   1586  N N   . PHE A 1 359 ? 146.006 111.122 91.814  1.00 63.67  ? 359  PHE A N   1 
ATOM   1587  C CA  . PHE A 1 359 ? 146.041 112.576 91.907  1.00 63.67  ? 359  PHE A CA  1 
ATOM   1588  C C   . PHE A 1 359 ? 146.640 113.028 93.234  1.00 63.67  ? 359  PHE A C   1 
ATOM   1589  O O   . PHE A 1 359 ? 147.335 114.048 93.298  1.00 63.67  ? 359  PHE A O   1 
ATOM   1590  C CB  . PHE A 1 359 ? 144.626 113.132 91.728  1.00 63.67  ? 359  PHE A CB  1 
ATOM   1591  C CG  . PHE A 1 359 ? 144.565 114.629 91.612  1.00 63.67  ? 359  PHE A CG  1 
ATOM   1592  C CD1 . PHE A 1 359 ? 143.469 115.322 92.095  1.00 63.67  ? 359  PHE A CD1 1 
ATOM   1593  C CD2 . PHE A 1 359 ? 145.582 115.343 91.002  1.00 63.67  ? 359  PHE A CD2 1 
ATOM   1594  C CE1 . PHE A 1 359 ? 143.405 116.691 92.000  1.00 63.67  ? 359  PHE A CE1 1 
ATOM   1595  C CE2 . PHE A 1 359 ? 145.519 116.718 90.904  1.00 63.67  ? 359  PHE A CE2 1 
ATOM   1596  C CZ  . PHE A 1 359 ? 144.425 117.393 91.401  1.00 63.67  ? 359  PHE A CZ  1 
ATOM   1597  N N   . ILE A 1 360 ? 146.398 112.275 94.306  1.00 64.48  ? 360  ILE A N   1 
ATOM   1598  C CA  . ILE A 1 360 ? 146.744 112.782 95.627  1.00 64.48  ? 360  ILE A CA  1 
ATOM   1599  C C   . ILE A 1 360 ? 148.201 112.502 96.001  1.00 64.48  ? 360  ILE A C   1 
ATOM   1600  O O   . ILE A 1 360 ? 148.833 113.339 96.660  1.00 64.48  ? 360  ILE A O   1 
ATOM   1601  C CB  . ILE A 1 360 ? 145.748 112.218 96.664  1.00 64.48  ? 360  ILE A CB  1 
ATOM   1602  C CG1 . ILE A 1 360 ? 145.976 112.831 98.047  1.00 64.48  ? 360  ILE A CG1 1 
ATOM   1603  C CG2 . ILE A 1 360 ? 145.796 110.696 96.734  1.00 64.48  ? 360  ILE A CG2 1 
ATOM   1604  C CD1 . ILE A 1 360 ? 145.713 114.311 98.073  1.00 64.48  ? 360  ILE A CD1 1 
ATOM   1605  N N   . LYS A 1 361 ? 148.786 111.391 95.547  1.00 67.35  ? 361  LYS A N   1 
ATOM   1606  C CA  . LYS A 1 361 ? 150.005 110.909 96.187  1.00 67.35  ? 361  LYS A CA  1 
ATOM   1607  C C   . LYS A 1 361 ? 151.237 111.225 95.343  1.00 67.35  ? 361  LYS A C   1 
ATOM   1608  O O   . LYS A 1 361 ? 152.325 111.474 95.877  1.00 67.35  ? 361  LYS A O   1 
ATOM   1609  C CB  . LYS A 1 361 ? 149.863 109.405 96.473  1.00 67.35  ? 361  LYS A CB  1 
ATOM   1610  C CG  . LYS A 1 361 ? 151.141 108.633 96.778  1.00 67.35  ? 361  LYS A CG  1 
ATOM   1611  C CD  . LYS A 1 361 ? 150.830 107.188 97.128  1.00 67.35  ? 361  LYS A CD  1 
ATOM   1612  C CE  . LYS A 1 361 ? 151.921 106.584 98.000  1.00 67.35  ? 361  LYS A CE  1 
ATOM   1613  N NZ  . LYS A 1 361 ? 151.447 105.371 98.726  1.00 67.35  ? 361  LYS A NZ  1 
ATOM   1614  N N   . HIS A 1 362 ? 151.079 111.292 94.023  1.00 72.01  ? 362  HIS A N   1 
ATOM   1615  C CA  . HIS A 1 362 ? 152.229 111.611 93.180  1.00 72.01  ? 362  HIS A CA  1 
ATOM   1616  C C   . HIS A 1 362 ? 151.976 112.671 92.121  1.00 72.01  ? 362  HIS A C   1 
ATOM   1617  O O   . HIS A 1 362 ? 152.948 113.152 91.528  1.00 72.01  ? 362  HIS A O   1 
ATOM   1618  C CB  . HIS A 1 362 ? 152.763 110.346 92.499  1.00 72.01  ? 362  HIS A CB  1 
ATOM   1619  C CG  . HIS A 1 362 ? 153.899 109.706 93.235  1.00 72.01  ? 362  HIS A CG  1 
ATOM   1620  N ND1 . HIS A 1 362 ? 155.207 110.116 93.086  1.00 72.01  ? 362  HIS A ND1 1 
ATOM   1621  C CD2 . HIS A 1 362 ? 153.923 108.696 94.136  1.00 72.01  ? 362  HIS A CD2 1 
ATOM   1622  C CE1 . HIS A 1 362 ? 155.988 109.380 93.857  1.00 72.01  ? 362  HIS A CE1 1 
ATOM   1623  N NE2 . HIS A 1 362 ? 155.233 108.511 94.505  1.00 72.01  ? 362  HIS A NE2 1 
ATOM   1624  N N   . LEU A 1 363 ? 150.732 113.069 91.857  1.00 65.97  ? 363  LEU A N   1 
ATOM   1625  C CA  . LEU A 1 363 ? 150.495 114.080 90.832  1.00 65.97  ? 363  LEU A CA  1 
ATOM   1626  C C   . LEU A 1 363 ? 150.740 115.478 91.386  1.00 65.97  ? 363  LEU A C   1 
ATOM   1627  O O   . LEU A 1 363 ? 151.689 116.160 90.984  1.00 65.97  ? 363  LEU A O   1 
ATOM   1628  C CB  . LEU A 1 363 ? 149.069 113.950 90.294  1.00 65.97  ? 363  LEU A CB  1 
ATOM   1629  C CG  . LEU A 1 363 ? 148.692 114.485 88.907  1.00 65.97  ? 363  LEU A CG  1 
ATOM   1630  C CD1 . LEU A 1 363 ? 147.494 113.703 88.394  1.00 65.97  ? 363  LEU A CD1 1 
ATOM   1631  C CD2 . LEU A 1 363 ? 148.404 115.980 88.866  1.00 65.97  ? 363  LEU A CD2 1 
ATOM   1632  N N   . ALA A 1 364 ? 149.900 115.916 92.324  1.00 61.91  ? 364  ALA A N   1 
ATOM   1633  C CA  . ALA A 1 364 ? 149.979 117.279 92.829  1.00 61.91  ? 364  ALA A CA  1 
ATOM   1634  C C   . ALA A 1 364 ? 151.018 117.443 93.927  1.00 61.91  ? 364  ALA A C   1 
ATOM   1635  O O   . ALA A 1 364 ? 151.265 118.572 94.364  1.00 61.91  ? 364  ALA A O   1 
ATOM   1636  C CB  . ALA A 1 364 ? 148.611 117.730 93.349  1.00 61.91  ? 364  ALA A CB  1 
ATOM   1637  N N   . GLY A 1 365 ? 151.626 116.353 94.382  1.00 61.57  ? 365  GLY A N   1 
ATOM   1638  C CA  . GLY A 1 365 ? 152.577 116.422 95.471  1.00 61.57  ? 365  GLY A CA  1 
ATOM   1639  C C   . GLY A 1 365 ? 152.116 115.637 96.679  1.00 61.57  ? 365  GLY A C   1 
ATOM   1640  O O   . GLY A 1 365 ? 151.495 114.579 96.538  1.00 61.57  ? 365  GLY A O   1 
ATOM   1641  N N   . GLU A 1 366 ? 152.402 116.147 97.877  1.00 67.77  ? 366  GLU A N   1 
ATOM   1642  C CA  . GLU A 1 366 ? 152.067 115.428 99.097  1.00 67.77  ? 366  GLU A CA  1 
ATOM   1643  C C   . GLU A 1 366 ? 150.992 116.107 99.933  1.00 67.77  ? 366  GLU A C   1 
ATOM   1644  O O   . GLU A 1 366 ? 150.695 115.620 101.027 1.00 67.77  ? 366  GLU A O   1 
ATOM   1645  C CB  . GLU A 1 366 ? 153.320 115.238 99.971  1.00 67.77  ? 366  GLU A CB  1 
ATOM   1646  C CG  . GLU A 1 366 ? 154.408 114.328 99.404  1.00 67.77  ? 366  GLU A CG  1 
ATOM   1647  C CD  . GLU A 1 366 ? 153.877 113.212 98.526  1.00 67.77  ? 366  GLU A CD  1 
ATOM   1648  O OE1 . GLU A 1 366 ? 154.041 113.306 97.293  1.00 67.77  ? 366  GLU A OE1 1 
ATOM   1649  O OE2 . GLU A 1 366 ? 153.297 112.247 99.064  1.00 67.77  ? 366  GLU A OE2 1 
ATOM   1650  N N   . ASN A 1 367 ? 150.400 117.201 99.464  1.00 69.60  ? 367  ASN A N   1 
ATOM   1651  C CA  . ASN A 1 367 ? 149.502 117.995 100.290 1.00 69.60  ? 367  ASN A CA  1 
ATOM   1652  C C   . ASN A 1 367 ? 148.075 117.453 100.193 1.00 69.60  ? 367  ASN A C   1 
ATOM   1653  O O   . ASN A 1 367 ? 147.795 116.479 99.492  1.00 69.60  ? 367  ASN A O   1 
ATOM   1654  C CB  . ASN A 1 367 ? 149.585 119.463 99.882  1.00 69.60  ? 367  ASN A CB  1 
ATOM   1655  C CG  . ASN A 1 367 ? 150.926 120.084 100.215 1.00 69.60  ? 367  ASN A CG  1 
ATOM   1656  O OD1 . ASN A 1 367 ? 151.483 119.846 101.286 1.00 69.60  ? 367  ASN A OD1 1 
ATOM   1657  N ND2 . ASN A 1 367 ? 151.456 120.881 99.295  1.00 69.60  ? 367  ASN A ND2 1 
ATOM   1658  N N   . ARG A 1 368 ? 147.156 118.091 100.915 1.00 63.91  ? 368  ARG A N   1 
ATOM   1659  C CA  . ARG A 1 368 ? 145.735 117.777 100.869 1.00 63.91  ? 368  ARG A CA  1 
ATOM   1660  C C   . ARG A 1 368 ? 144.880 118.942 100.406 1.00 63.91  ? 368  ARG A C   1 
ATOM   1661  O O   . ARG A 1 368 ? 143.830 118.718 99.801  1.00 63.91  ? 368  ARG A O   1 
ATOM   1662  C CB  . ARG A 1 368 ? 145.235 117.328 102.251 1.00 63.91  ? 368  ARG A CB  1 
ATOM   1663  C CG  . ARG A 1 368 ? 145.246 115.826 102.478 1.00 63.91  ? 368  ARG A CG  1 
ATOM   1664  C CD  . ARG A 1 368 ? 144.414 115.097 101.434 1.00 63.91  ? 368  ARG A CD  1 
ATOM   1665  N NE  . ARG A 1 368 ? 142.981 115.329 101.589 1.00 63.91  ? 368  ARG A NE  1 
ATOM   1666  C CZ  . ARG A 1 368 ? 142.236 116.000 100.718 1.00 63.91  ? 368  ARG A CZ  1 
ATOM   1667  N NH1 . ARG A 1 368 ? 142.788 116.511 99.628  1.00 63.91  ? 368  ARG A NH1 1 
ATOM   1668  N NH2 . ARG A 1 368 ? 140.940 116.163 100.937 1.00 63.91  ? 368  ARG A NH2 1 
ATOM   1669  N N   . ARG A 1 369 ? 145.303 120.176 100.674 1.00 60.03  ? 369  ARG A N   1 
ATOM   1670  C CA  . ARG A 1 369 ? 144.605 121.376 100.236 1.00 60.03  ? 369  ARG A CA  1 
ATOM   1671  C C   . ARG A 1 369 ? 145.131 121.903 98.910  1.00 60.03  ? 369  ARG A C   1 
ATOM   1672  O O   . ARG A 1 369 ? 144.362 122.460 98.120  1.00 60.03  ? 369  ARG A O   1 
ATOM   1673  C CB  . ARG A 1 369 ? 144.725 122.475 101.300 1.00 60.03  ? 369  ARG A CB  1 
ATOM   1674  C CG  . ARG A 1 369 ? 143.718 122.407 102.461 1.00 60.03  ? 369  ARG A CG  1 
ATOM   1675  C CD  . ARG A 1 369 ? 142.256 122.168 102.055 1.00 60.03  ? 369  ARG A CD  1 
ATOM   1676  N NE  . ARG A 1 369 ? 141.794 123.001 100.944 1.00 60.03  ? 369  ARG A NE  1 
ATOM   1677  C CZ  . ARG A 1 369 ? 140.702 122.748 100.228 1.00 60.03  ? 369  ARG A CZ  1 
ATOM   1678  N NH1 . ARG A 1 369 ? 139.950 121.694 100.516 1.00 60.03  ? 369  ARG A NH1 1 
ATOM   1679  N NH2 . ARG A 1 369 ? 140.354 123.553 99.235  1.00 60.03  ? 369  ARG A NH2 1 
ATOM   1680  N N   . LYS A 1 370 ? 146.434 121.750 98.658  1.00 62.97  ? 370  LYS A N   1 
ATOM   1681  C CA  . LYS A 1 370 ? 146.996 122.116 97.362  1.00 62.97  ? 370  LYS A CA  1 
ATOM   1682  C C   . LYS A 1 370 ? 146.509 121.179 96.265  1.00 62.97  ? 370  LYS A C   1 
ATOM   1683  O O   . LYS A 1 370 ? 146.282 121.615 95.131  1.00 62.97  ? 370  LYS A O   1 
ATOM   1684  C CB  . LYS A 1 370 ? 148.523 122.114 97.446  1.00 62.97  ? 370  LYS A CB  1 
ATOM   1685  C CG  . LYS A 1 370 ? 149.245 122.562 96.186  1.00 62.97  ? 370  LYS A CG  1 
ATOM   1686  C CD  . LYS A 1 370 ? 150.126 121.447 95.645  1.00 62.97  ? 370  LYS A CD  1 
ATOM   1687  C CE  . LYS A 1 370 ? 151.233 121.993 94.761  1.00 62.97  ? 370  LYS A CE  1 
ATOM   1688  N NZ  . LYS A 1 370 ? 152.068 120.903 94.188  1.00 62.97  ? 370  LYS A NZ  1 
ATOM   1689  N N   . ALA A 1 371 ? 146.320 119.898 96.589  1.00 59.69  ? 371  ALA A N   1 
ATOM   1690  C CA  . ALA A 1 371 ? 145.734 118.970 95.630  1.00 59.69  ? 371  ALA A CA  1 
ATOM   1691  C C   . ALA A 1 371 ? 144.250 119.242 95.420  1.00 59.69  ? 371  ALA A C   1 
ATOM   1692  O O   . ALA A 1 371 ? 143.701 118.897 94.368  1.00 59.69  ? 371  ALA A O   1 
ATOM   1693  C CB  . ALA A 1 371 ? 145.948 117.530 96.093  1.00 59.69  ? 371  ALA A CB  1 
ATOM   1694  N N   . MET A 1 372 ? 143.590 119.857 96.399  1.00 60.54  ? 372  MET A N   1 
ATOM   1695  C CA  . MET A 1 372 ? 142.166 120.139 96.269  1.00 60.54  ? 372  MET A CA  1 
ATOM   1696  C C   . MET A 1 372 ? 141.923 121.406 95.459  1.00 60.54  ? 372  MET A C   1 
ATOM   1697  O O   . MET A 1 372 ? 140.916 121.508 94.752  1.00 60.54  ? 372  MET A O   1 
ATOM   1698  C CB  . MET A 1 372 ? 141.539 120.273 97.656  1.00 60.54  ? 372  MET A CB  1 
ATOM   1699  C CG  . MET A 1 372 ? 140.140 119.690 97.814  1.00 60.54  ? 372  MET A CG  1 
ATOM   1700  S SD  . MET A 1 372 ? 140.022 117.910 97.544  1.00 60.54  ? 372  MET A SD  1 
ATOM   1701  C CE  . MET A 1 372 ? 139.189 117.860 95.966  1.00 60.54  ? 372  MET A CE  1 
ATOM   1702  N N   . LYS A 1 373 ? 142.840 122.374 95.545  1.00 59.04  ? 373  LYS A N   1 
ATOM   1703  C CA  . LYS A 1 373 ? 142.603 123.696 94.969  1.00 59.04  ? 373  LYS A CA  1 
ATOM   1704  C C   . LYS A 1 373 ? 142.725 123.676 93.448  1.00 59.04  ? 373  LYS A C   1 
ATOM   1705  O O   . LYS A 1 373 ? 142.126 124.516 92.765  1.00 59.04  ? 373  LYS A O   1 
ATOM   1706  C CB  . LYS A 1 373 ? 143.574 124.699 95.612  1.00 59.04  ? 373  LYS A CB  1 
ATOM   1707  C CG  . LYS A 1 373 ? 143.501 126.160 95.152  1.00 59.04  ? 373  LYS A CG  1 
ATOM   1708  C CD  . LYS A 1 373 ? 144.630 126.511 94.186  1.00 59.04  ? 373  LYS A CD  1 
ATOM   1709  C CE  . LYS A 1 373 ? 145.994 126.276 94.819  1.00 59.04  ? 373  LYS A CE  1 
ATOM   1710  N NZ  . LYS A 1 373 ? 147.095 126.418 93.831  1.00 59.04  ? 373  LYS A NZ  1 
ATOM   1711  N N   . TYR A 1 374 ? 143.449 122.696 92.895  1.00 62.28  ? 374  TYR A N   1 
ATOM   1712  C CA  . TYR A 1 374 ? 143.646 122.622 91.449  1.00 62.28  ? 374  TYR A CA  1 
ATOM   1713  C C   . TYR A 1 374 ? 142.386 122.241 90.678  1.00 62.28  ? 374  TYR A C   1 
ATOM   1714  O O   . TYR A 1 374 ? 142.383 122.340 89.446  1.00 62.28  ? 374  TYR A O   1 
ATOM   1715  C CB  . TYR A 1 374 ? 144.750 121.619 91.105  1.00 62.28  ? 374  TYR A CB  1 
ATOM   1716  C CG  . TYR A 1 374 ? 146.160 122.120 91.317  1.00 62.28  ? 374  TYR A CG  1 
ATOM   1717  C CD1 . TYR A 1 374 ? 146.419 123.471 91.526  1.00 62.28  ? 374  TYR A CD1 1 
ATOM   1718  C CD2 . TYR A 1 374 ? 147.239 121.242 91.272  1.00 62.28  ? 374  TYR A CD2 1 
ATOM   1719  C CE1 . TYR A 1 374 ? 147.714 123.931 91.706  1.00 62.28  ? 374  TYR A CE1 1 
ATOM   1720  C CE2 . TYR A 1 374 ? 148.537 121.693 91.450  1.00 62.28  ? 374  TYR A CE2 1 
ATOM   1721  C CZ  . TYR A 1 374 ? 148.767 123.038 91.666  1.00 62.28  ? 374  TYR A CZ  1 
ATOM   1722  O OH  . TYR A 1 374 ? 150.053 123.492 91.845  1.00 62.28  ? 374  TYR A OH  1 
ATOM   1723  N N   . LEU A 1 375 ? 141.325 121.792 91.352  1.00 59.99  ? 375  LEU A N   1 
ATOM   1724  C CA  . LEU A 1 375 ? 140.153 121.330 90.619  1.00 59.99  ? 375  LEU A CA  1 
ATOM   1725  C C   . LEU A 1 375 ? 138.835 121.682 91.308  1.00 59.99  ? 375  LEU A C   1 
ATOM   1726  O O   . LEU A 1 375 ? 137.786 121.157 90.917  1.00 59.99  ? 375  LEU A O   1 
ATOM   1727  C CB  . LEU A 1 375 ? 140.257 119.816 90.379  1.00 59.99  ? 375  LEU A CB  1 
ATOM   1728  C CG  . LEU A 1 375 ? 139.904 118.740 91.416  1.00 59.99  ? 375  LEU A CG  1 
ATOM   1729  C CD1 . LEU A 1 375 ? 140.074 117.365 90.781  1.00 59.99  ? 375  LEU A CD1 1 
ATOM   1730  C CD2 . LEU A 1 375 ? 140.684 118.853 92.708  1.00 59.99  ? 375  LEU A CD2 1 
ATOM   1731  N N   . LYS A 1 376 ? 138.845 122.578 92.297  1.00 57.54  ? 376  LYS A N   1 
ATOM   1732  C CA  . LYS A 1 376 ? 137.639 122.862 93.062  1.00 57.54  ? 376  LYS A CA  1 
ATOM   1733  C C   . LYS A 1 376 ? 137.187 124.300 92.865  1.00 57.54  ? 376  LYS A C   1 
ATOM   1734  O O   . LYS A 1 376 ? 137.734 125.203 93.517  1.00 57.54  ? 376  LYS A O   1 
ATOM   1735  C CB  . LYS A 1 376 ? 137.872 122.595 94.543  1.00 57.54  ? 376  LYS A CB  1 
ATOM   1736  C CG  . LYS A 1 376 ? 137.620 121.166 94.984  1.00 57.54  ? 376  LYS A CG  1 
ATOM   1737  C CD  . LYS A 1 376 ? 136.154 120.948 95.312  1.00 57.54  ? 376  LYS A CD  1 
ATOM   1738  C CE  . LYS A 1 376 ? 135.953 119.688 96.141  1.00 57.54  ? 376  LYS A CE  1 
ATOM   1739  N NZ  . LYS A 1 376 ? 136.281 119.905 97.579  1.00 57.54  ? 376  LYS A NZ  1 
ATOM   1740  N N   . PRO A 1 377 ? 136.216 124.570 91.992  1.00 61.00  ? 377  PRO A N   1 
ATOM   1741  C CA  . PRO A 1 377 ? 135.379 125.761 92.177  1.00 61.00  ? 377  PRO A CA  1 
ATOM   1742  C C   . PRO A 1 377 ? 134.276 125.452 93.177  1.00 61.00  ? 377  PRO A C   1 
ATOM   1743  O O   . PRO A 1 377 ? 134.077 124.274 93.496  1.00 61.00  ? 377  PRO A O   1 
ATOM   1744  C CB  . PRO A 1 377 ? 134.830 126.033 90.774  1.00 61.00  ? 377  PRO A CB  1 
ATOM   1745  C CG  . PRO A 1 377 ? 134.831 124.702 90.113  1.00 61.00  ? 377  PRO A CG  1 
ATOM   1746  C CD  . PRO A 1 377 ? 136.009 123.949 90.673  1.00 61.00  ? 377  PRO A CD  1 
ATOM   1747  N N   . HIS A 1 378 ? 133.539 126.478 93.631  1.00 65.79  ? 378  HIS A N   1 
ATOM   1748  C CA  . HIS A 1 378 ? 132.699 126.416 94.836  1.00 65.79  ? 378  HIS A CA  1 
ATOM   1749  C C   . HIS A 1 378 ? 133.476 125.833 96.011  1.00 65.79  ? 378  HIS A C   1 
ATOM   1750  O O   . HIS A 1 378 ? 133.024 124.874 96.643  1.00 65.79  ? 378  HIS A O   1 
ATOM   1751  C CB  . HIS A 1 378 ? 131.400 125.629 94.600  1.00 65.79  ? 378  HIS A CB  1 
ATOM   1752  C CG  . HIS A 1 378 ? 130.286 125.995 95.536  1.00 65.79  ? 378  HIS A CG  1 
ATOM   1753  N ND1 . HIS A 1 378 ? 130.436 126.015 96.906  1.00 65.79  ? 378  HIS A ND1 1 
ATOM   1754  C CD2 . HIS A 1 378 ? 129.002 126.347 95.294  1.00 65.79  ? 378  HIS A CD2 1 
ATOM   1755  C CE1 . HIS A 1 378 ? 129.295 126.370 97.468  1.00 65.79  ? 378  HIS A CE1 1 
ATOM   1756  N NE2 . HIS A 1 378 ? 128.408 126.576 96.512  1.00 65.79  ? 378  HIS A NE2 1 
ATOM   1757  N N   . HIS A 1 379 ? 134.647 126.423 96.273  1.00 61.80  ? 379  HIS A N   1 
ATOM   1758  C CA  . HIS A 1 379 ? 135.755 125.850 97.035  1.00 61.80  ? 379  HIS A CA  1 
ATOM   1759  C C   . HIS A 1 379 ? 135.384 125.330 98.420  1.00 61.80  ? 379  HIS A C   1 
ATOM   1760  O O   . HIS A 1 379 ? 135.405 124.116 98.650  1.00 61.80  ? 379  HIS A O   1 
ATOM   1761  C CB  . HIS A 1 379 ? 136.885 126.886 97.156  1.00 61.80  ? 379  HIS A CB  1 
ATOM   1762  C CG  . HIS A 1 379 ? 136.414 128.291 97.393  1.00 61.80  ? 379  HIS A CG  1 
ATOM   1763  N ND1 . HIS A 1 379 ? 136.379 128.861 98.648  1.00 61.80  ? 379  HIS A ND1 1 
ATOM   1764  C CD2 . HIS A 1 379 ? 135.987 129.250 96.535  1.00 61.80  ? 379  HIS A CD2 1 
ATOM   1765  C CE1 . HIS A 1 379 ? 135.932 130.101 98.555  1.00 61.80  ? 379  HIS A CE1 1 
ATOM   1766  N NE2 . HIS A 1 379 ? 135.686 130.361 97.284  1.00 61.80  ? 379  HIS A NE2 1 
ATOM   1767  N N   . ARG A 1 380 ? 134.992 126.231 99.319  1.00 56.68  ? 380  ARG A N   1 
ATOM   1768  C CA  . ARG A 1 380 ? 134.733 125.908 100.716 1.00 56.68  ? 380  ARG A CA  1 
ATOM   1769  C C   . ARG A 1 380 ? 134.036 127.104 101.351 1.00 56.68  ? 380  ARG A C   1 
ATOM   1770  O O   . ARG A 1 380 ? 134.353 128.251 101.023 1.00 56.68  ? 380  ARG A O   1 
ATOM   1771  C CB  . ARG A 1 380 ? 136.048 125.568 101.441 1.00 56.68  ? 380  ARG A CB  1 
ATOM   1772  C CG  . ARG A 1 380 ? 135.948 125.279 102.935 1.00 56.68  ? 380  ARG A CG  1 
ATOM   1773  C CD  . ARG A 1 380 ? 134.913 124.206 103.260 1.00 56.68  ? 380  ARG A CD  1 
ATOM   1774  N NE  . ARG A 1 380 ? 134.949 123.817 104.669 1.00 56.68  ? 380  ARG A NE  1 
ATOM   1775  C CZ  . ARG A 1 380 ? 135.785 122.917 105.176 1.00 56.68  ? 380  ARG A CZ  1 
ATOM   1776  N NH1 . ARG A 1 380 ? 136.658 122.302 104.391 1.00 56.68  ? 380  ARG A NH1 1 
ATOM   1777  N NH2 . ARG A 1 380 ? 135.748 122.625 106.469 1.00 56.68  ? 380  ARG A NH2 1 
ATOM   1778  N N   . LYS A 1 381 ? 133.088 126.862 102.252 1.00 52.93  ? 381  LYS A N   1 
ATOM   1779  C CA  . LYS A 1 381 ? 132.492 127.952 103.008 1.00 52.93  ? 381  LYS A CA  1 
ATOM   1780  C C   . LYS A 1 381 ? 133.414 128.356 104.154 1.00 52.93  ? 381  LYS A C   1 
ATOM   1781  O O   . LYS A 1 381 ? 134.572 127.942 104.234 1.00 52.93  ? 381  LYS A O   1 
ATOM   1782  C CB  . LYS A 1 381 ? 131.128 127.551 103.559 1.00 52.93  ? 381  LYS A CB  1 
ATOM   1783  C CG  . LYS A 1 381 ? 130.073 127.332 102.503 1.00 52.93  ? 381  LYS A CG  1 
ATOM   1784  C CD  . LYS A 1 381 ? 128.770 126.916 103.145 1.00 52.93  ? 381  LYS A CD  1 
ATOM   1785  C CE  . LYS A 1 381 ? 127.689 126.715 102.100 1.00 52.93  ? 381  LYS A CE  1 
ATOM   1786  N NZ  . LYS A 1 381 ? 126.424 126.284 102.743 1.00 52.93  ? 381  LYS A NZ  1 
ATOM   1787  N N   . GLU A 1 382 ? 132.892 129.177 105.058 1.00 49.37  ? 382  GLU A N   1 
ATOM   1788  C CA  . GLU A 1 382 ? 133.721 129.579 106.180 1.00 49.37  ? 382  GLU A CA  1 
ATOM   1789  C C   . GLU A 1 382 ? 133.849 128.434 107.183 1.00 49.37  ? 382  GLU A C   1 
ATOM   1790  O O   . GLU A 1 382 ? 132.904 127.684 107.442 1.00 49.37  ? 382  GLU A O   1 
ATOM   1791  C CB  . GLU A 1 382 ? 133.157 130.828 106.858 1.00 49.37  ? 382  GLU A CB  1 
ATOM   1792  C CG  . GLU A 1 382 ? 134.211 131.612 107.627 1.00 49.37  ? 382  GLU A CG  1 
ATOM   1793  C CD  . GLU A 1 382 ? 134.256 131.253 109.099 1.00 49.37  ? 382  GLU A CD  1 
ATOM   1794  O OE1 . GLU A 1 382 ? 135.197 131.691 109.791 1.00 49.37  ? 382  GLU A OE1 1 
ATOM   1795  O OE2 . GLU A 1 382 ? 133.339 130.550 109.570 1.00 49.37  ? 382  GLU A OE2 1 
ATOM   1796  N N   . SER A 1 383 ? 135.053 128.289 107.730 1.00 47.74  ? 383  SER A N   1 
ATOM   1797  C CA  . SER A 1 383 ? 135.311 127.287 108.757 1.00 47.74  ? 383  SER A CA  1 
ATOM   1798  C C   . SER A 1 383 ? 134.645 127.750 110.041 1.00 47.74  ? 383  SER A C   1 
ATOM   1799  O O   . SER A 1 383 ? 135.181 128.605 110.753 1.00 47.74  ? 383  SER A O   1 
ATOM   1800  C CB  . SER A 1 383 ? 136.810 127.089 108.960 1.00 47.74  ? 383  SER A CB  1 
ATOM   1801  O OG  . SER A 1 383 ? 137.317 128.025 109.895 1.00 47.74  ? 383  SER A OG  1 
ATOM   1802  N N   . HIS A 1 384 ? 133.487 127.178 110.352 1.00 37.46  ? 384  HIS A N   1 
ATOM   1803  C CA  . HIS A 1 384 ? 132.695 127.642 111.487 1.00 37.46  ? 384  HIS A CA  1 
ATOM   1804  C C   . HIS A 1 384 ? 133.092 126.944 112.780 1.00 37.46  ? 384  HIS A C   1 
ATOM   1805  O O   . HIS A 1 384 ? 132.263 126.464 113.551 1.00 37.46  ? 384  HIS A O   1 
ATOM   1806  C CB  . HIS A 1 384 ? 131.217 127.453 111.188 1.00 37.46  ? 384  HIS A CB  1 
ATOM   1807  C CG  . HIS A 1 384 ? 130.694 128.398 110.155 1.00 37.46  ? 384  HIS A CG  1 
ATOM   1808  N ND1 . HIS A 1 384 ? 130.789 128.152 108.803 1.00 37.46  ? 384  HIS A ND1 1 
ATOM   1809  C CD2 . HIS A 1 384 ? 130.085 129.601 110.277 1.00 37.46  ? 384  HIS A CD2 1 
ATOM   1810  C CE1 . HIS A 1 384 ? 130.253 129.159 108.137 1.00 37.46  ? 384  HIS A CE1 1 
ATOM   1811  N NE2 . HIS A 1 384 ? 129.816 130.050 109.008 1.00 37.46  ? 384  HIS A NE2 1 
ATOM   1812  N N   . SER A 1 385 ? 134.401 126.921 113.023 1.00 27.83  ? 385  SER A N   1 
ATOM   1813  C CA  . SER A 1 385 ? 134.977 126.612 114.316 1.00 27.83  ? 385  SER A CA  1 
ATOM   1814  C C   . SER A 1 385 ? 135.260 127.877 115.098 1.00 27.83  ? 385  SER A C   1 
ATOM   1815  O O   . SER A 1 385 ? 135.997 127.843 116.084 1.00 27.83  ? 385  SER A O   1 
ATOM   1816  C CB  . SER A 1 385 ? 136.257 125.799 114.147 1.00 27.83  ? 385  SER A CB  1 
ATOM   1817  O OG  . SER A 1 385 ? 137.321 126.632 113.737 1.00 27.83  ? 385  SER A OG  1 
ATOM   1818  N N   . VAL A 1 386 ? 134.714 129.000 114.646 1.00 18.73  ? 386  VAL A N   1 
ATOM   1819  C CA  . VAL A 1 386 ? 134.806 130.253 115.376 1.00 18.73  ? 386  VAL A CA  1 
ATOM   1820  C C   . VAL A 1 386 ? 133.438 130.838 115.678 1.00 18.73  ? 386  VAL A C   1 
ATOM   1821  O O   . VAL A 1 386 ? 133.327 131.676 116.577 1.00 18.73  ? 386  VAL A O   1 
ATOM   1822  C CB  . VAL A 1 386 ? 135.680 131.274 114.613 1.00 18.73  ? 386  VAL A CB  1 
ATOM   1823  C CG1 . VAL A 1 386 ? 134.914 131.927 113.477 1.00 18.73  ? 386  VAL A CG1 1 
ATOM   1824  C CG2 . VAL A 1 386 ? 136.324 132.287 115.540 1.00 18.73  ? 386  VAL A CG2 1 
ATOM   1825  N N   . THR A 1 387 ? 132.374 130.405 115.002 1.00 11.91  ? 387  THR A N   1 
ATOM   1826  C CA  . THR A 1 387 ? 131.037 130.733 115.471 1.00 11.91  ? 387  THR A CA  1 
ATOM   1827  C C   . THR A 1 387 ? 130.697 129.902 116.695 1.00 11.91  ? 387  THR A C   1 
ATOM   1828  O O   . THR A 1 387 ? 129.904 130.320 117.545 1.00 11.91  ? 387  THR A O   1 
ATOM   1829  C CB  . THR A 1 387 ? 130.030 130.494 114.355 1.00 11.91  ? 387  THR A CB  1 
ATOM   1830  O OG1 . THR A 1 387 ? 130.526 131.084 113.154 1.00 11.91  ? 387  THR A OG1 1 
ATOM   1831  C CG2 . THR A 1 387 ? 128.705 131.156 114.670 1.00 11.91  ? 387  THR A CG2 1 
ATOM   1832  N N   . PHE A 1 388 ? 131.315 128.732 116.809 1.00 9.78   ? 388  PHE A N   1 
ATOM   1833  C CA  . PHE A 1 388 ? 131.163 127.902 117.993 1.00 9.78   ? 388  PHE A CA  1 
ATOM   1834  C C   . PHE A 1 388 ? 131.953 128.467 119.166 1.00 9.78   ? 388  PHE A C   1 
ATOM   1835  O O   . PHE A 1 388 ? 131.442 128.527 120.286 1.00 9.78   ? 388  PHE A O   1 
ATOM   1836  C CB  . PHE A 1 388 ? 131.607 126.475 117.651 1.00 9.78   ? 388  PHE A CB  1 
ATOM   1837  C CG  . PHE A 1 388 ? 131.447 125.495 118.765 1.00 9.78   ? 388  PHE A CG  1 
ATOM   1838  C CD1 . PHE A 1 388 ? 132.526 125.137 119.545 1.00 9.78   ? 388  PHE A CD1 1 
ATOM   1839  C CD2 . PHE A 1 388 ? 130.227 124.914 119.015 1.00 9.78   ? 388  PHE A CD2 1 
ATOM   1840  C CE1 . PHE A 1 388 ? 132.383 124.242 120.559 1.00 9.78   ? 388  PHE A CE1 1 
ATOM   1841  C CE2 . PHE A 1 388 ? 130.087 124.015 120.033 1.00 9.78   ? 388  PHE A CE2 1 
ATOM   1842  C CZ  . PHE A 1 388 ? 131.166 123.684 120.805 1.00 9.78   ? 388  PHE A CZ  1 
ATOM   1843  N N   . PHE A 1 389 ? 133.174 128.918 118.927 1.00 12.74  ? 389  PHE A N   1 
ATOM   1844  C CA  . PHE A 1 389 ? 134.042 129.375 119.998 1.00 12.74  ? 389  PHE A CA  1 
ATOM   1845  C C   . PHE A 1 389 ? 133.681 130.771 120.494 1.00 12.74  ? 389  PHE A C   1 
ATOM   1846  O O   . PHE A 1 389 ? 134.075 131.142 121.602 1.00 12.74  ? 389  PHE A O   1 
ATOM   1847  C CB  . PHE A 1 389 ? 135.499 129.330 119.539 1.00 12.74  ? 389  PHE A CB  1 
ATOM   1848  C CG  . PHE A 1 389 ? 136.145 127.972 119.666 1.00 12.74  ? 389  PHE A CG  1 
ATOM   1849  C CD1 . PHE A 1 389 ? 137.289 127.811 120.426 1.00 12.74  ? 389  PHE A CD1 1 
ATOM   1850  C CD2 . PHE A 1 389 ? 135.616 126.862 119.024 1.00 12.74  ? 389  PHE A CD2 1 
ATOM   1851  C CE1 . PHE A 1 389 ? 137.886 126.573 120.543 1.00 12.74  ? 389  PHE A CE1 1 
ATOM   1852  C CE2 . PHE A 1 389 ? 136.208 125.631 119.137 1.00 12.74  ? 389  PHE A CE2 1 
ATOM   1853  C CZ  . PHE A 1 389 ? 137.341 125.484 119.897 1.00 12.74  ? 389  PHE A CZ  1 
ATOM   1854  N N   . ILE A 1 390 ? 132.967 131.563 119.693 1.00 12.07  ? 390  ILE A N   1 
ATOM   1855  C CA  . ILE A 1 390 ? 132.218 132.693 120.227 1.00 12.07  ? 390  ILE A CA  1 
ATOM   1856  C C   . ILE A 1 390 ? 131.122 132.210 121.164 1.00 12.07  ? 390  ILE A C   1 
ATOM   1857  O O   . ILE A 1 390 ? 130.985 132.742 122.272 1.00 12.07  ? 390  ILE A O   1 
ATOM   1858  C CB  . ILE A 1 390 ? 131.597 133.536 119.099 1.00 12.07  ? 390  ILE A CB  1 
ATOM   1859  C CG1 . ILE A 1 390 ? 132.656 134.279 118.317 1.00 12.07  ? 390  ILE A CG1 1 
ATOM   1860  C CG2 . ILE A 1 390 ? 130.649 134.557 119.629 1.00 12.07  ? 390  ILE A CG2 1 
ATOM   1861  C CD1 . ILE A 1 390 ? 132.148 134.755 116.988 1.00 12.07  ? 390  ILE A CD1 1 
ATOM   1862  N N   . GLY A 1 391 ? 130.379 131.181 120.779 1.00 7.20   ? 391  GLY A N   1 
ATOM   1863  C CA  . GLY A 1 391 ? 129.294 130.687 121.588 1.00 7.20   ? 391  GLY A CA  1 
ATOM   1864  C C   . GLY A 1 391 ? 129.731 129.925 122.816 1.00 7.20   ? 391  GLY A C   1 
ATOM   1865  O O   . GLY A 1 391 ? 129.055 130.001 123.843 1.00 7.20   ? 391  GLY A O   1 
ATOM   1866  N N   . LEU A 1 392 ? 130.837 129.178 122.720 1.00 8.91   ? 392  LEU A N   1 
ATOM   1867  C CA  . LEU A 1 392 ? 131.345 128.421 123.862 1.00 8.91   ? 392  LEU A CA  1 
ATOM   1868  C C   . LEU A 1 392 ? 131.708 129.351 125.004 1.00 8.91   ? 392  LEU A C   1 
ATOM   1869  O O   . LEU A 1 392 ? 131.436 129.054 126.169 1.00 8.91   ? 392  LEU A O   1 
ATOM   1870  C CB  . LEU A 1 392 ? 132.569 127.606 123.455 1.00 8.91   ? 392  LEU A CB  1 
ATOM   1871  C CG  . LEU A 1 392 ? 133.028 126.323 124.157 1.00 8.91   ? 392  LEU A CG  1 
ATOM   1872  C CD1 . LEU A 1 392 ? 134.128 125.722 123.329 1.00 8.91   ? 392  LEU A CD1 1 
ATOM   1873  C CD2 . LEU A 1 392 ? 133.512 126.476 125.586 1.00 8.91   ? 392  LEU A CD2 1 
ATOM   1874  N N   . PHE A 1 393 ? 132.308 130.489 124.683 1.00 7.07   ? 393  PHE A N   1 
ATOM   1875  C CA  . PHE A 1 393 ? 132.778 131.415 125.694 1.00 7.07   ? 393  PHE A CA  1 
ATOM   1876  C C   . PHE A 1 393 ? 131.765 132.492 126.038 1.00 7.07   ? 393  PHE A C   1 
ATOM   1877  O O   . PHE A 1 393 ? 131.911 133.137 127.076 1.00 7.07   ? 393  PHE A O   1 
ATOM   1878  C CB  . PHE A 1 393 ? 134.073 132.036 125.219 1.00 7.07   ? 393  PHE A CB  1 
ATOM   1879  C CG  . PHE A 1 393 ? 135.237 131.113 125.303 1.00 7.07   ? 393  PHE A CG  1 
ATOM   1880  C CD1 . PHE A 1 393 ? 135.729 130.723 126.531 1.00 7.07   ? 393  PHE A CD1 1 
ATOM   1881  C CD2 . PHE A 1 393 ? 135.845 130.643 124.163 1.00 7.07   ? 393  PHE A CD2 1 
ATOM   1882  C CE1 . PHE A 1 393 ? 136.804 129.883 126.618 1.00 7.07   ? 393  PHE A CE1 1 
ATOM   1883  C CE2 . PHE A 1 393 ? 136.917 129.804 124.244 1.00 7.07   ? 393  PHE A CE2 1 
ATOM   1884  C CZ  . PHE A 1 393 ? 137.399 129.425 125.473 1.00 7.07   ? 393  PHE A CZ  1 
ATOM   1885  N N   . THR A 1 394 ? 130.756 132.710 125.196 1.00 5.26   ? 394  THR A N   1 
ATOM   1886  C CA  . THR A 1 394 ? 129.612 133.517 125.601 1.00 5.26   ? 394  THR A CA  1 
ATOM   1887  C C   . THR A 1 394 ? 128.840 132.829 126.713 1.00 5.26   ? 394  THR A C   1 
ATOM   1888  O O   . THR A 1 394 ? 128.547 133.437 127.744 1.00 5.26   ? 394  THR A O   1 
ATOM   1889  C CB  . THR A 1 394 ? 128.697 133.778 124.408 1.00 5.26   ? 394  THR A CB  1 
ATOM   1890  O OG1 . THR A 1 394 ? 129.349 134.660 123.495 1.00 5.26   ? 394  THR A OG1 1 
ATOM   1891  C CG2 . THR A 1 394 ? 127.393 134.396 124.845 1.00 5.26   ? 394  THR A CG2 1 
ATOM   1892  N N   . GLY A 1 395 ? 128.520 131.552 126.533 1.00 5.46   ? 395  GLY A N   1 
ATOM   1893  C CA  . GLY A 1 395 ? 127.757 130.850 127.545 1.00 5.46   ? 395  GLY A CA  1 
ATOM   1894  C C   . GLY A 1 395 ? 128.559 130.516 128.782 1.00 5.46   ? 395  GLY A C   1 
ATOM   1895  O O   . GLY A 1 395 ? 127.998 130.392 129.870 1.00 5.46   ? 395  GLY A O   1 
ATOM   1896  N N   . CYS A 1 396 ? 129.873 130.360 128.640 1.00 6.71   ? 396  CYS A N   1 
ATOM   1897  C CA  . CYS A 1 396 ? 130.702 130.071 129.800 1.00 6.71   ? 396  CYS A CA  1 
ATOM   1898  C C   . CYS A 1 396 ? 130.867 131.292 130.689 1.00 6.71   ? 396  CYS A C   1 
ATOM   1899  O O   . CYS A 1 396 ? 130.910 131.150 131.913 1.00 6.71   ? 396  CYS A O   1 
ATOM   1900  C CB  . CYS A 1 396 ? 132.061 129.543 129.349 1.00 6.71   ? 396  CYS A CB  1 
ATOM   1901  S SG  . CYS A 1 396 ? 133.272 129.347 130.645 1.00 6.71   ? 396  CYS A SG  1 
ATOM   1902  N N   . PHE A 1 397 ? 130.922 132.486 130.103 1.00 6.90   ? 397  PHE A N   1 
ATOM   1903  C CA  . PHE A 1 397 ? 130.921 133.742 130.840 1.00 6.90   ? 397  PHE A CA  1 
ATOM   1904  C C   . PHE A 1 397 ? 129.588 134.036 131.510 1.00 6.90   ? 397  PHE A C   1 
ATOM   1905  O O   . PHE A 1 397 ? 129.572 134.478 132.659 1.00 6.90   ? 397  PHE A O   1 
ATOM   1906  C CB  . PHE A 1 397 ? 131.312 134.889 129.906 1.00 6.90   ? 397  PHE A CB  1 
ATOM   1907  C CG  . PHE A 1 397 ? 130.879 136.236 130.387 1.00 6.90   ? 397  PHE A CG  1 
ATOM   1908  C CD1 . PHE A 1 397 ? 131.431 136.813 131.516 1.00 6.90   ? 397  PHE A CD1 1 
ATOM   1909  C CD2 . PHE A 1 397 ? 129.930 136.948 129.675 1.00 6.90   ? 397  PHE A CD2 1 
ATOM   1910  C CE1 . PHE A 1 397 ? 131.000 138.044 131.956 1.00 6.90   ? 397  PHE A CE1 1 
ATOM   1911  C CE2 . PHE A 1 397 ? 129.510 138.177 130.105 1.00 6.90   ? 397  PHE A CE2 1 
ATOM   1912  C CZ  . PHE A 1 397 ? 130.045 138.725 131.245 1.00 6.90   ? 397  PHE A CZ  1 
ATOM   1913  N N   . VAL A 1 398 ? 128.472 133.813 130.817 1.00 6.42   ? 398  VAL A N   1 
ATOM   1914  C CA  . VAL A 1 398 ? 127.163 134.121 131.382 1.00 6.42   ? 398  VAL A CA  1 
ATOM   1915  C C   . VAL A 1 398 ? 126.836 133.195 132.548 1.00 6.42   ? 398  VAL A C   1 
ATOM   1916  O O   . VAL A 1 398 ? 126.348 133.649 133.588 1.00 6.42   ? 398  VAL A O   1 
ATOM   1917  C CB  . VAL A 1 398 ? 126.097 134.061 130.273 1.00 6.42   ? 398  VAL A CB  1 
ATOM   1918  C CG1 . VAL A 1 398 ? 124.707 134.073 130.843 1.00 6.42   ? 398  VAL A CG1 1 
ATOM   1919  C CG2 . VAL A 1 398 ? 126.264 135.222 129.339 1.00 6.42   ? 398  VAL A CG2 1 
ATOM   1920  N N   . ALA A 1 399 ? 127.158 131.909 132.438 1.00 7.37   ? 399  ALA A N   1 
ATOM   1921  C CA  . ALA A 1 399 ? 126.870 130.972 133.514 1.00 7.37   ? 399  ALA A CA  1 
ATOM   1922  C C   . ALA A 1 399 ? 127.836 131.079 134.683 1.00 7.37   ? 399  ALA A C   1 
ATOM   1923  O O   . ALA A 1 399 ? 127.463 130.739 135.809 1.00 7.37   ? 399  ALA A O   1 
ATOM   1924  C CB  . ALA A 1 399 ? 126.885 129.546 132.982 1.00 7.37   ? 399  ALA A CB  1 
ATOM   1925  N N   . LEU A 1 400 ? 129.071 131.526 134.451 1.00 10.95  ? 400  LEU A N   1 
ATOM   1926  C CA  . LEU A 1 400 ? 129.980 131.840 135.547 1.00 10.95  ? 400  LEU A CA  1 
ATOM   1927  C C   . LEU A 1 400 ? 129.640 133.155 136.233 1.00 10.95  ? 400  LEU A C   1 
ATOM   1928  O O   . LEU A 1 400 ? 129.839 133.274 137.446 1.00 10.95  ? 400  LEU A O   1 
ATOM   1929  C CB  . LEU A 1 400 ? 131.415 131.889 135.045 1.00 10.95  ? 400  LEU A CB  1 
ATOM   1930  C CG  . LEU A 1 400 ? 132.120 130.546 135.113 1.00 10.95  ? 400  LEU A CG  1 
ATOM   1931  C CD1 . LEU A 1 400 ? 133.300 130.496 134.182 1.00 10.95  ? 400  LEU A CD1 1 
ATOM   1932  C CD2 . LEU A 1 400 ? 132.559 130.315 136.526 1.00 10.95  ? 400  LEU A CD2 1 
ATOM   1933  N N   . LEU A 1 401 ? 129.147 134.142 135.485 1.00 16.72  ? 401  LEU A N   1 
ATOM   1934  C CA  . LEU A 1 401 ? 128.549 135.322 136.091 1.00 16.72  ? 401  LEU A CA  1 
ATOM   1935  C C   . LEU A 1 401 ? 127.287 134.982 136.864 1.00 16.72  ? 401  LEU A C   1 
ATOM   1936  O O   . LEU A 1 401 ? 127.144 135.410 138.009 1.00 16.72  ? 401  LEU A O   1 
ATOM   1937  C CB  . LEU A 1 401 ? 128.219 136.362 135.024 1.00 16.72  ? 401  LEU A CB  1 
ATOM   1938  C CG  . LEU A 1 401 ? 127.311 137.507 135.469 1.00 16.72  ? 401  LEU A CG  1 
ATOM   1939  C CD1 . LEU A 1 401 ? 128.074 138.458 136.355 1.00 16.72  ? 401  LEU A CD1 1 
ATOM   1940  C CD2 . LEU A 1 401 ? 126.698 138.226 134.284 1.00 16.72  ? 401  LEU A CD2 1 
ATOM   1941  N N   . ALA A 1 402 ? 126.369 134.214 136.277 1.00 22.03  ? 402  ALA A N   1 
ATOM   1942  C CA  . ALA A 1 402 ? 125.137 133.865 136.972 1.00 22.03  ? 402  ALA A CA  1 
ATOM   1943  C C   . ALA A 1 402 ? 125.369 132.926 138.145 1.00 22.03  ? 402  ALA A C   1 
ATOM   1944  O O   . ALA A 1 402 ? 124.519 132.849 139.036 1.00 22.03  ? 402  ALA A O   1 
ATOM   1945  C CB  . ALA A 1 402 ? 124.136 133.241 136.004 1.00 22.03  ? 402  ALA A CB  1 
ATOM   1946  N N   . GLY A 1 403 ? 126.499 132.233 138.179 1.00 25.47  ? 403  GLY A N   1 
ATOM   1947  C CA  . GLY A 1 403 ? 126.911 131.521 139.367 1.00 25.47  ? 403  GLY A CA  1 
ATOM   1948  C C   . GLY A 1 403 ? 127.863 132.358 140.190 1.00 25.47  ? 403  GLY A C   1 
ATOM   1949  O O   . GLY A 1 403 ? 128.827 131.838 140.749 1.00 25.47  ? 403  GLY A O   1 
ATOM   1950  N N   . TYR A 1 404 ? 127.631 133.670 140.213 1.00 26.10  ? 404  TYR A N   1 
ATOM   1951  C CA  . TYR A 1 404 ? 128.358 134.611 141.053 1.00 26.10  ? 404  TYR A CA  1 
ATOM   1952  C C   . TYR A 1 404 ? 127.365 135.602 141.640 1.00 26.10  ? 404  TYR A C   1 
ATOM   1953  O O   . TYR A 1 404 ? 127.640 136.230 142.660 1.00 26.10  ? 404  TYR A O   1 
ATOM   1954  C CB  . TYR A 1 404 ? 129.454 135.310 140.246 1.00 26.10  ? 404  TYR A CB  1 
ATOM   1955  C CG  . TYR A 1 404 ? 130.267 136.347 140.977 1.00 26.10  ? 404  TYR A CG  1 
ATOM   1956  C CD1 . TYR A 1 404 ? 129.907 137.688 140.949 1.00 26.10  ? 404  TYR A CD1 1 
ATOM   1957  C CD2 . TYR A 1 404 ? 131.419 135.994 141.657 1.00 26.10  ? 404  TYR A CD2 1 
ATOM   1958  C CE1 . TYR A 1 404 ? 130.651 138.639 141.605 1.00 26.10  ? 404  TYR A CE1 1 
ATOM   1959  C CE2 . TYR A 1 404 ? 132.171 136.942 142.315 1.00 26.10  ? 404  TYR A CE2 1 
ATOM   1960  C CZ  . TYR A 1 404 ? 131.783 138.260 142.283 1.00 26.10  ? 404  TYR A CZ  1 
ATOM   1961  O OH  . TYR A 1 404 ? 132.532 139.205 142.936 1.00 26.10  ? 404  TYR A OH  1 
ATOM   1962  N N   . ILE A 1 405 ? 126.201 135.749 141.003 1.00 35.63  ? 405  ILE A N   1 
ATOM   1963  C CA  . ILE A 1 405 ? 125.106 136.526 141.571 1.00 35.63  ? 405  ILE A CA  1 
ATOM   1964  C C   . ILE A 1 405 ? 124.083 135.631 142.265 1.00 35.63  ? 405  ILE A C   1 
ATOM   1965  O O   . ILE A 1 405 ? 123.024 136.111 142.697 1.00 35.63  ? 405  ILE A O   1 
ATOM   1966  C CB  . ILE A 1 405 ? 124.432 137.402 140.496 1.00 35.63  ? 405  ILE A CB  1 
ATOM   1967  C CG1 . ILE A 1 405 ? 125.439 137.804 139.435 1.00 35.63  ? 405  ILE A CG1 1 
ATOM   1968  C CG2 . ILE A 1 405 ? 123.952 138.718 141.081 1.00 35.63  ? 405  ILE A CG2 1 
ATOM   1969  C CD1 . ILE A 1 405 ? 124.801 138.418 138.221 1.00 35.63  ? 405  ILE A CD1 1 
ATOM   1970  N N   . ILE A 1 406 ? 124.367 134.332 142.377 1.00 50.84  ? 406  ILE A N   1 
ATOM   1971  C CA  . ILE A 1 406 ? 123.616 133.428 143.235 1.00 50.84  ? 406  ILE A CA  1 
ATOM   1972  C C   . ILE A 1 406 ? 124.412 133.049 144.475 1.00 50.84  ? 406  ILE A C   1 
ATOM   1973  O O   . ILE A 1 406 ? 123.895 133.127 145.596 1.00 50.84  ? 406  ILE A O   1 
ATOM   1974  C CB  . ILE A 1 406 ? 123.170 132.164 142.462 1.00 50.84  ? 406  ILE A CB  1 
ATOM   1975  C CG1 . ILE A 1 406 ? 122.016 132.498 141.522 1.00 50.84  ? 406  ILE A CG1 1 
ATOM   1976  C CG2 . ILE A 1 406 ? 122.740 131.049 143.401 1.00 50.84  ? 406  ILE A CG2 1 
ATOM   1977  C CD1 . ILE A 1 406 ? 120.763 132.948 142.235 1.00 50.84  ? 406  ILE A CD1 1 
ATOM   1978  N N   . VAL A 1 407 ? 125.684 132.689 144.306 1.00 52.62  ? 407  VAL A N   1 
ATOM   1979  C CA  . VAL A 1 407 ? 126.487 132.272 145.448 1.00 52.62  ? 407  VAL A CA  1 
ATOM   1980  C C   . VAL A 1 407 ? 126.843 133.465 146.337 1.00 52.62  ? 407  VAL A C   1 
ATOM   1981  O O   . VAL A 1 407 ? 126.786 133.361 147.564 1.00 52.62  ? 407  VAL A O   1 
ATOM   1982  C CB  . VAL A 1 407 ? 127.726 131.484 144.969 1.00 52.62  ? 407  VAL A CB  1 
ATOM   1983  C CG1 . VAL A 1 407 ? 128.517 132.253 143.954 1.00 52.62  ? 407  VAL A CG1 1 
ATOM   1984  C CG2 . VAL A 1 407 ? 128.616 131.079 146.130 1.00 52.62  ? 407  VAL A CG2 1 
ATOM   1985  N N   . ALA A 1 408 ? 127.146 134.632 145.754 1.00 55.74  ? 408  ALA A N   1 
ATOM   1986  C CA  . ALA A 1 408 ? 127.453 135.791 146.587 1.00 55.74  ? 408  ALA A CA  1 
ATOM   1987  C C   . ALA A 1 408 ? 126.199 136.372 147.213 1.00 55.74  ? 408  ALA A C   1 
ATOM   1988  O O   . ALA A 1 408 ? 126.281 137.031 148.254 1.00 55.74  ? 408  ALA A O   1 
ATOM   1989  C CB  . ALA A 1 408 ? 128.171 136.869 145.785 1.00 55.74  ? 408  ALA A CB  1 
ATOM   1990  N N   . HIS A 1 409 ? 125.045 136.154 146.584 1.00 55.69  ? 409  HIS A N   1 
ATOM   1991  C CA  . HIS A 1 409 ? 123.771 136.450 147.227 1.00 55.69  ? 409  HIS A CA  1 
ATOM   1992  C C   . HIS A 1 409 ? 123.591 135.595 148.475 1.00 55.69  ? 409  HIS A C   1 
ATOM   1993  O O   . HIS A 1 409 ? 123.151 136.080 149.523 1.00 55.69  ? 409  HIS A O   1 
ATOM   1994  C CB  . HIS A 1 409 ? 122.636 136.210 146.234 1.00 55.69  ? 409  HIS A CB  1 
ATOM   1995  C CG  . HIS A 1 409 ? 121.416 137.036 146.487 1.00 55.69  ? 409  HIS A CG  1 
ATOM   1996  N ND1 . HIS A 1 409 ? 120.605 136.850 147.585 1.00 55.69  ? 409  HIS A ND1 1 
ATOM   1997  C CD2 . HIS A 1 409 ? 120.855 138.039 145.772 1.00 55.69  ? 409  HIS A CD2 1 
ATOM   1998  C CE1 . HIS A 1 409 ? 119.604 137.710 147.541 1.00 55.69  ? 409  HIS A CE1 1 
ATOM   1999  N NE2 . HIS A 1 409 ? 119.732 138.443 146.450 1.00 55.69  ? 409  HIS A NE2 1 
ATOM   2000  N N   . LEU A 1 410 ? 123.934 134.319 148.378 1.00 56.38  ? 410  LEU A N   1 
ATOM   2001  C CA  . LEU A 1 410 ? 123.836 133.377 149.491 1.00 56.38  ? 410  LEU A CA  1 
ATOM   2002  C C   . LEU A 1 410 ? 125.177 133.256 150.217 1.00 56.38  ? 410  LEU A C   1 
ATOM   2003  O O   . LEU A 1 410 ? 125.731 132.187 150.441 1.00 56.38  ? 410  LEU A O   1 
ATOM   2004  C CB  . LEU A 1 410 ? 123.319 132.042 148.952 1.00 56.38  ? 410  LEU A CB  1 
ATOM   2005  C CG  . LEU A 1 410 ? 122.925 130.750 149.669 1.00 56.38  ? 410  LEU A CG  1 
ATOM   2006  C CD1 . LEU A 1 410 ? 121.687 130.281 148.959 1.00 56.38  ? 410  LEU A CD1 1 
ATOM   2007  C CD2 . LEU A 1 410 ? 123.974 129.663 149.561 1.00 56.38  ? 410  LEU A CD2 1 
ATOM   2008  N N   . THR A 1 411 ? 125.742 134.403 150.577 1.00 55.12  ? 411  THR A N   1 
ATOM   2009  C CA  . THR A 1 411 ? 126.960 134.445 151.373 1.00 55.12  ? 411  THR A CA  1 
ATOM   2010  C C   . THR A 1 411 ? 126.887 135.553 152.415 1.00 55.12  ? 411  THR A C   1 
ATOM   2011  O O   . THR A 1 411 ? 127.700 135.567 153.346 1.00 55.12  ? 411  THR A O   1 
ATOM   2012  C CB  . THR A 1 411 ? 128.198 134.642 150.448 1.00 55.12  ? 411  THR A CB  1 
ATOM   2013  O OG1 . THR A 1 411 ? 128.093 133.780 149.316 1.00 55.12  ? 411  THR A OG1 1 
ATOM   2014  C CG2 . THR A 1 411 ? 129.520 134.292 151.122 1.00 55.12  ? 411  THR A CG2 1 
ATOM   2015  N N   . GLY A 1 412 ? 125.869 136.405 152.373 1.00 65.66  ? 412  GLY A N   1 
ATOM   2016  C CA  . GLY A 1 412 ? 126.066 137.680 153.017 1.00 65.66  ? 412  GLY A CA  1 
ATOM   2017  C C   . GLY A 1 412 ? 126.735 139.001 152.706 1.00 65.66  ? 412  GLY A C   1 
ATOM   2018  O O   . GLY A 1 412 ? 126.632 139.956 153.480 1.00 65.66  ? 412  GLY A O   1 
ATOM   2019  N N   . MET A 1 413 ? 127.411 139.049 151.554 1.00 73.28  ? 413  MET A N   1 
ATOM   2020  C CA  . MET A 1 413 ? 128.467 139.971 151.130 1.00 73.28  ? 413  MET A CA  1 
ATOM   2021  C C   . MET A 1 413 ? 127.806 140.794 150.019 1.00 73.28  ? 413  MET A C   1 
ATOM   2022  O O   . MET A 1 413 ? 128.234 141.929 149.778 1.00 73.28  ? 413  MET A O   1 
ATOM   2023  C CB  . MET A 1 413 ? 129.794 139.417 150.598 1.00 73.28  ? 413  MET A CB  1 
ATOM   2024  C CG  . MET A 1 413 ? 130.324 138.241 151.420 1.00 73.28  ? 413  MET A CG  1 
ATOM   2025  S SD  . MET A 1 413 ? 131.644 137.265 150.666 1.00 73.28  ? 413  MET A SD  1 
ATOM   2026  C CE  . MET A 1 413 ? 133.002 138.427 150.659 1.00 73.28  ? 413  MET A CE  1 
ATOM   2027  N N   . TYR A 1 414 ? 126.805 140.228 149.325 1.00 73.91  ? 414  TYR A N   1 
ATOM   2028  C CA  . TYR A 1 414 ? 126.116 140.906 148.222 1.00 73.91  ? 414  TYR A CA  1 
ATOM   2029  C C   . TYR A 1 414 ? 125.499 142.243 148.635 1.00 73.91  ? 414  TYR A C   1 
ATOM   2030  O O   . TYR A 1 414 ? 125.447 143.184 147.834 1.00 73.91  ? 414  TYR A O   1 
ATOM   2031  C CB  . TYR A 1 414 ? 125.039 139.978 147.654 1.00 73.91  ? 414  TYR A CB  1 
ATOM   2032  C CG  . TYR A 1 414 ? 123.989 140.637 146.782 1.00 73.91  ? 414  TYR A CG  1 
ATOM   2033  C CD1 . TYR A 1 414 ? 122.672 140.750 147.216 1.00 73.91  ? 414  TYR A CD1 1 
ATOM   2034  C CD2 . TYR A 1 414 ? 124.307 141.122 145.518 1.00 73.91  ? 414  TYR A CD2 1 
ATOM   2035  C CE1 . TYR A 1 414 ? 121.703 141.341 146.423 1.00 73.91  ? 414  TYR A CE1 1 
ATOM   2036  C CE2 . TYR A 1 414 ? 123.344 141.715 144.714 1.00 73.91  ? 414  TYR A CE2 1 
ATOM   2037  C CZ  . TYR A 1 414 ? 122.044 141.821 145.173 1.00 73.91  ? 414  TYR A CZ  1 
ATOM   2038  O OH  . TYR A 1 414 ? 121.084 142.410 144.380 1.00 73.91  ? 414  TYR A OH  1 
ATOM   2039  N N   . ARG A 1 415 ? 125.032 142.353 149.875 1.00 74.50  ? 415  ARG A N   1 
ATOM   2040  C CA  . ARG A 1 415 ? 124.619 143.636 150.428 1.00 74.50  ? 415  ARG A CA  1 
ATOM   2041  C C   . ARG A 1 415 ? 125.579 144.144 151.491 1.00 74.50  ? 415  ARG A C   1 
ATOM   2042  O O   . ARG A 1 415 ? 125.268 145.144 152.150 1.00 74.50  ? 415  ARG A O   1 
ATOM   2043  C CB  . ARG A 1 415 ? 123.209 143.545 151.021 1.00 74.50  ? 415  ARG A CB  1 
ATOM   2044  C CG  . ARG A 1 415 ? 122.089 143.412 150.004 1.00 74.50  ? 415  ARG A CG  1 
ATOM   2045  C CD  . ARG A 1 415 ? 120.753 143.205 150.709 1.00 74.50  ? 415  ARG A CD  1 
ATOM   2046  N NE  . ARG A 1 415 ? 119.632 143.115 149.780 1.00 74.50  ? 415  ARG A NE  1 
ATOM   2047  C CZ  . ARG A 1 415 ? 119.269 142.000 149.156 1.00 74.50  ? 415  ARG A CZ  1 
ATOM   2048  N NH1 . ARG A 1 415 ? 118.233 142.011 148.331 1.00 74.50  ? 415  ARG A NH1 1 
ATOM   2049  N NH2 . ARG A 1 415 ? 119.939 140.873 149.356 1.00 74.50  ? 415  ARG A NH2 1 
ATOM   2050  N N   . GLN A 1 416 ? 126.731 143.484 151.654 1.00 67.96  ? 416  GLN A N   1 
ATOM   2051  C CA  . GLN A 1 416 ? 127.715 143.742 152.713 1.00 67.96  ? 416  GLN A CA  1 
ATOM   2052  C C   . GLN A 1 416 ? 127.078 143.726 154.104 1.00 67.96  ? 416  GLN A C   1 
ATOM   2053  O O   . GLN A 1 416 ? 127.310 144.603 154.938 1.00 67.96  ? 416  GLN A O   1 
ATOM   2054  C CB  . GLN A 1 416 ? 128.478 145.044 152.464 1.00 67.96  ? 416  GLN A CB  1 
ATOM   2055  C CG  . GLN A 1 416 ? 129.723 144.837 151.632 1.00 67.96  ? 416  GLN A CG  1 
ATOM   2056  C CD  . GLN A 1 416 ? 130.770 144.009 152.352 1.00 67.96  ? 416  GLN A CD  1 
ATOM   2057  O OE1 . GLN A 1 416 ? 130.991 144.172 153.550 1.00 67.96  ? 416  GLN A OE1 1 
ATOM   2058  N NE2 . GLN A 1 416 ? 131.404 143.098 151.626 1.00 67.96  ? 416  GLN A NE2 1 
ATOM   2059  N N   . HIS A 1 417 ? 126.258 142.705 154.345 1.00 71.49  ? 417  HIS A N   1 
ATOM   2060  C CA  . HIS A 1 417 ? 125.705 142.417 155.665 1.00 71.49  ? 417  HIS A CA  1 
ATOM   2061  C C   . HIS A 1 417 ? 126.398 141.215 156.295 1.00 71.49  ? 417  HIS A C   1 
ATOM   2062  O O   . HIS A 1 417 ? 125.772 140.368 156.938 1.00 71.49  ? 417  HIS A O   1 
ATOM   2063  C CB  . HIS A 1 417 ? 124.192 142.222 155.588 1.00 71.49  ? 417  HIS A CB  1 
ATOM   2064  C CG  . HIS A 1 417 ? 123.757 141.079 154.724 1.00 71.49  ? 417  HIS A CG  1 
ATOM   2065  N ND1 . HIS A 1 417 ? 123.517 139.818 155.226 1.00 71.49  ? 417  HIS A ND1 1 
ATOM   2066  C CD2 . HIS A 1 417 ? 123.500 141.010 153.397 1.00 71.49  ? 417  HIS A CD2 1 
ATOM   2067  C CE1 . HIS A 1 417 ? 123.131 139.022 154.245 1.00 71.49  ? 417  HIS A CE1 1 
ATOM   2068  N NE2 . HIS A 1 417 ? 123.120 139.719 153.123 1.00 71.49  ? 417  HIS A NE2 1 
ATOM   2069  N N   . SER A 1 418 ? 127.712 141.138 156.123 1.00 66.69  ? 418  SER A N   1 
ATOM   2070  C CA  . SER A 1 418 ? 128.480 139.931 156.384 1.00 66.69  ? 418  SER A CA  1 
ATOM   2071  C C   . SER A 1 418 ? 129.835 140.329 156.956 1.00 66.69  ? 418  SER A C   1 
ATOM   2072  O O   . SER A 1 418 ? 129.980 141.406 157.546 1.00 66.69  ? 418  SER A O   1 
ATOM   2073  C CB  . SER A 1 418 ? 128.644 139.107 155.101 1.00 66.69  ? 418  SER A CB  1 
ATOM   2074  O OG  . SER A 1 418 ? 129.796 139.527 154.394 1.00 66.69  ? 418  SER A OG  1 
ATOM   2075  N N   . ALA A 1 419 ? 130.825 139.455 156.772 1.00 61.61  ? 419  ALA A N   1 
ATOM   2076  C CA  . ALA A 1 419 ? 132.193 139.620 157.255 1.00 61.61  ? 419  ALA A CA  1 
ATOM   2077  C C   . ALA A 1 419 ? 132.959 140.710 156.504 1.00 61.61  ? 419  ALA A C   1 
ATOM   2078  O O   . ALA A 1 419 ? 132.348 141.533 155.812 1.00 61.61  ? 419  ALA A O   1 
ATOM   2079  C CB  . ALA A 1 419 ? 132.946 138.291 157.161 1.00 61.61  ? 419  ALA A CB  1 
ATOM   2080  N N   . ASN A 1 420 ? 134.289 140.725 156.695 1.00 58.42  ? 420  ASN A N   1 
ATOM   2081  C CA  . ASN A 1 420 ? 135.212 141.793 156.295 1.00 58.42  ? 420  ASN A CA  1 
ATOM   2082  C C   . ASN A 1 420 ? 135.000 142.294 154.869 1.00 58.42  ? 420  ASN A C   1 
ATOM   2083  O O   . ASN A 1 420 ? 134.645 141.532 153.967 1.00 58.42  ? 420  ASN A O   1 
ATOM   2084  C CB  . ASN A 1 420 ? 136.655 141.301 156.448 1.00 58.42  ? 420  ASN A CB  1 
ATOM   2085  C CG  . ASN A 1 420 ? 136.847 139.873 155.954 1.00 58.42  ? 420  ASN A CG  1 
ATOM   2086  O OD1 . ASN A 1 420 ? 136.486 139.530 154.827 1.00 58.42  ? 420  ASN A OD1 1 
ATOM   2087  N ND2 . ASN A 1 420 ? 137.423 139.033 156.803 1.00 58.42  ? 420  ASN A ND2 1 
ATOM   2088  N N   . THR A 1 421 ? 135.218 143.597 154.684 1.00 55.64  ? 421  THR A N   1 
ATOM   2089  C CA  . THR A 1 421 ? 134.896 144.300 153.450 1.00 55.64  ? 421  THR A CA  1 
ATOM   2090  C C   . THR A 1 421 ? 136.062 144.249 152.443 1.00 55.64  ? 421  THR A C   1 
ATOM   2091  O O   . THR A 1 421 ? 136.250 145.149 151.618 1.00 55.64  ? 421  THR A O   1 
ATOM   2092  C CB  . THR A 1 421 ? 134.480 145.740 153.785 1.00 55.64  ? 421  THR A CB  1 
ATOM   2093  O OG1 . THR A 1 421 ? 133.699 145.716 154.983 1.00 55.64  ? 421  THR A OG1 1 
ATOM   2094  C CG2 . THR A 1 421 ? 133.548 146.331 152.715 1.00 55.64  ? 421  THR A CG2 1 
ATOM   2095  N N   . PHE A 1 422 ? 136.876 143.196 152.486 1.00 59.68  ? 422  PHE A N   1 
ATOM   2096  C CA  . PHE A 1 422 ? 137.878 142.971 151.442 1.00 59.68  ? 422  PHE A CA  1 
ATOM   2097  C C   . PHE A 1 422 ? 137.281 142.252 150.235 1.00 59.68  ? 422  PHE A C   1 
ATOM   2098  O O   . PHE A 1 422 ? 137.885 141.343 149.669 1.00 59.68  ? 422  PHE A O   1 
ATOM   2099  C CB  . PHE A 1 422 ? 139.041 142.172 152.011 1.00 59.68  ? 422  PHE A CB  1 
ATOM   2100  C CG  . PHE A 1 422 ? 139.931 142.954 152.919 1.00 59.68  ? 422  PHE A CG  1 
ATOM   2101  C CD1 . PHE A 1 422 ? 140.739 143.961 152.422 1.00 59.68  ? 422  PHE A CD1 1 
ATOM   2102  C CD2 . PHE A 1 422 ? 139.953 142.686 154.278 1.00 59.68  ? 422  PHE A CD2 1 
ATOM   2103  C CE1 . PHE A 1 422 ? 141.569 144.679 153.261 1.00 59.68  ? 422  PHE A CE1 1 
ATOM   2104  C CE2 . PHE A 1 422 ? 140.771 143.407 155.128 1.00 59.68  ? 422  PHE A CE2 1 
ATOM   2105  C CZ  . PHE A 1 422 ? 141.580 144.407 154.619 1.00 59.68  ? 422  PHE A CZ  1 
ATOM   2106  N N   . TYR A 1 423 ? 136.093 142.682 149.814 1.00 55.72  ? 423  TYR A N   1 
ATOM   2107  C CA  . TYR A 1 423 ? 135.444 142.208 148.604 1.00 55.72  ? 423  TYR A CA  1 
ATOM   2108  C C   . TYR A 1 423 ? 135.224 143.410 147.703 1.00 55.72  ? 423  TYR A C   1 
ATOM   2109  O O   . TYR A 1 423 ? 135.701 143.440 146.566 1.00 55.72  ? 423  TYR A O   1 
ATOM   2110  C CB  . TYR A 1 423 ? 134.135 141.488 148.963 1.00 55.72  ? 423  TYR A CB  1 
ATOM   2111  C CG  . TYR A 1 423 ? 133.075 141.380 147.878 1.00 55.72  ? 423  TYR A CG  1 
ATOM   2112  C CD1 . TYR A 1 423 ? 132.019 142.286 147.813 1.00 55.72  ? 423  TYR A CD1 1 
ATOM   2113  C CD2 . TYR A 1 423 ? 133.105 140.349 146.947 1.00 55.72  ? 423  TYR A CD2 1 
ATOM   2114  C CE1 . TYR A 1 423 ? 131.043 142.184 146.835 1.00 55.72  ? 423  TYR A CE1 1 
ATOM   2115  C CE2 . TYR A 1 423 ? 132.131 140.240 145.967 1.00 55.72  ? 423  TYR A CE2 1 
ATOM   2116  C CZ  . TYR A 1 423 ? 131.104 141.161 145.917 1.00 55.72  ? 423  TYR A CZ  1 
ATOM   2117  O OH  . TYR A 1 423 ? 130.130 141.066 144.948 1.00 55.72  ? 423  TYR A OH  1 
ATOM   2118  N N   . MET A 1 424 ? 134.558 144.433 148.234 1.00 51.85  ? 424  MET A N   1 
ATOM   2119  C CA  . MET A 1 424 ? 134.174 145.604 147.459 1.00 51.85  ? 424  MET A CA  1 
ATOM   2120  C C   . MET A 1 424 ? 135.238 146.689 147.458 1.00 51.85  ? 424  MET A C   1 
ATOM   2121  O O   . MET A 1 424 ? 134.960 147.813 147.031 1.00 51.85  ? 424  MET A O   1 
ATOM   2122  C CB  . MET A 1 424 ? 132.852 146.173 147.974 1.00 51.85  ? 424  MET A CB  1 
ATOM   2123  C CG  . MET A 1 424 ? 131.930 146.643 146.876 1.00 51.85  ? 424  MET A CG  1 
ATOM   2124  S SD  . MET A 1 424 ? 130.292 147.021 147.490 1.00 51.85  ? 424  MET A SD  1 
ATOM   2125  C CE  . MET A 1 424 ? 129.767 145.379 147.949 1.00 51.85  ? 424  MET A CE  1 
ATOM   2126  N N   . GLU A 1 425 ? 136.437 146.389 147.950 1.00 47.06  ? 425  GLU A N   1 
ATOM   2127  C CA  . GLU A 1 425 ? 137.584 147.269 147.806 1.00 47.06  ? 425  GLU A CA  1 
ATOM   2128  C C   . GLU A 1 425 ? 138.814 146.532 147.305 1.00 47.06  ? 425  GLU A C   1 
ATOM   2129  O O   . GLU A 1 425 ? 139.842 147.170 147.061 1.00 47.06  ? 425  GLU A O   1 
ATOM   2130  C CB  . GLU A 1 425 ? 137.909 147.975 149.133 1.00 47.06  ? 425  GLU A CB  1 
ATOM   2131  C CG  . GLU A 1 425 ? 136.772 148.821 149.690 1.00 47.06  ? 425  GLU A CG  1 
ATOM   2132  C CD  . GLU A 1 425 ? 136.819 148.970 151.192 1.00 47.06  ? 425  GLU A CD  1 
ATOM   2133  O OE1 . GLU A 1 425 ? 136.876 147.935 151.886 1.00 47.06  ? 425  GLU A OE1 1 
ATOM   2134  O OE2 . GLU A 1 425 ? 136.800 150.120 151.678 1.00 47.06  ? 425  GLU A OE2 1 
ATOM   2135  N N   . THR A 1 426 ? 138.739 145.213 147.144 1.00 43.72  ? 426  THR A N   1 
ATOM   2136  C CA  . THR A 1 426 ? 139.854 144.427 146.634 1.00 43.72  ? 426  THR A CA  1 
ATOM   2137  C C   . THR A 1 426 ? 139.625 144.011 145.189 1.00 43.72  ? 426  THR A C   1 
ATOM   2138  O O   . THR A 1 426 ? 140.459 144.285 144.323 1.00 43.72  ? 426  THR A O   1 
ATOM   2139  C CB  . THR A 1 426 ? 140.054 143.184 147.496 1.00 43.72  ? 426  THR A CB  1 
ATOM   2140  O OG1 . THR A 1 426 ? 138.811 142.475 147.588 1.00 43.72  ? 426  THR A OG1 1 
ATOM   2141  C CG2 . THR A 1 426 ? 140.505 143.591 148.871 1.00 43.72  ? 426  THR A CG2 1 
ATOM   2142  N N   . ALA A 1 427 ? 138.411 143.430 145.012 1.00 33.37  ? 427  ALA A N   1 
ATOM   2143  C CA  . ALA A 1 427 ? 137.945 142.918 143.706 1.00 33.37  ? 427  ALA A CA  1 
ATOM   2144  C C   . ALA A 1 427 ? 136.617 143.402 143.124 1.00 33.37  ? 427  ALA A C   1 
ATOM   2145  O O   . ALA A 1 427 ? 135.995 142.613 142.401 1.00 33.37  ? 427  ALA A O   1 
ATOM   2146  C CB  . ALA A 1 427 ? 137.962 141.427 143.673 1.00 33.37  ? 427  ALA A CB  1 
ATOM   2147  N N   . TYR A 1 428 ? 136.099 144.537 143.562 1.00 32.47  ? 428  TYR A N   1 
ATOM   2148  C CA  . TYR A 1 428 ? 135.057 145.284 142.813 1.00 32.47  ? 428  TYR A CA  1 
ATOM   2149  C C   . TYR A 1 428 ? 135.767 146.368 141.994 1.00 32.47  ? 428  TYR A C   1 
ATOM   2150  O O   . TYR A 1 428 ? 135.220 146.824 140.984 1.00 32.47  ? 428  TYR A O   1 
ATOM   2151  C CB  . TYR A 1 428 ? 133.993 145.850 143.742 1.00 32.47  ? 428  TYR A CB  1 
ATOM   2152  C CG  . TYR A 1 428 ? 132.886 146.596 143.045 1.00 32.47  ? 428  TYR A CG  1 
ATOM   2153  C CD1 . TYR A 1 428 ? 132.937 147.970 142.895 1.00 32.47  ? 428  TYR A CD1 1 
ATOM   2154  C CD2 . TYR A 1 428 ? 131.780 145.933 142.548 1.00 32.47  ? 428  TYR A CD2 1 
ATOM   2155  C CE1 . TYR A 1 428 ? 131.920 148.668 142.270 1.00 32.47  ? 428  TYR A CE1 1 
ATOM   2156  C CE2 . TYR A 1 428 ? 130.754 146.615 141.918 1.00 32.47  ? 428  TYR A CE2 1 
ATOM   2157  C CZ  . TYR A 1 428 ? 130.822 147.988 141.777 1.00 32.47  ? 428  TYR A CZ  1 
ATOM   2158  O OH  . TYR A 1 428 ? 129.814 148.672 141.159 1.00 32.47  ? 428  TYR A OH  1 
ATOM   2159  N N   . PRO A 1 429 ? 136.996 146.787 142.363 1.00 22.94  ? 429  PRO A N   1 
ATOM   2160  C CA  . PRO A 1 429 ? 137.793 147.600 141.493 1.00 22.94  ? 429  PRO A CA  1 
ATOM   2161  C C   . PRO A 1 429 ? 138.612 146.668 140.595 1.00 22.94  ? 429  PRO A C   1 
ATOM   2162  O O   . PRO A 1 429 ? 139.739 147.003 140.376 1.00 22.94  ? 429  PRO A O   1 
ATOM   2163  C CB  . PRO A 1 429 ? 138.746 148.347 142.406 1.00 22.94  ? 429  PRO A CB  1 
ATOM   2164  C CG  . PRO A 1 429 ? 138.660 147.625 143.707 1.00 22.94  ? 429  PRO A CG  1 
ATOM   2165  C CD  . PRO A 1 429 ? 137.217 147.197 143.771 1.00 22.94  ? 429  PRO A CD  1 
ATOM   2166  N N   . VAL A 1 430 ? 138.086 145.511 140.175 1.00 20.58  ? 430  VAL A N   1 
ATOM   2167  C CA  . VAL A 1 430 ? 138.734 144.637 139.129 1.00 20.58  ? 430  VAL A CA  1 
ATOM   2168  C C   . VAL A 1 430 ? 137.537 144.290 138.255 1.00 20.58  ? 430  VAL A C   1 
ATOM   2169  O O   . VAL A 1 430 ? 137.682 144.389 137.042 1.00 20.58  ? 430  VAL A O   1 
ATOM   2170  C CB  . VAL A 1 430 ? 139.687 143.553 139.640 1.00 20.58  ? 430  VAL A CB  1 
ATOM   2171  C CG1 . VAL A 1 430 ? 140.176 142.681 138.494 1.00 20.58  ? 430  VAL A CG1 1 
ATOM   2172  C CG2 . VAL A 1 430 ? 140.846 144.127 140.434 1.00 20.58  ? 430  VAL A CG2 1 
ATOM   2173  N N   . LEU A 1 431 ? 136.488 143.719 138.811 1.00 25.54  ? 431  LEU A N   1 
ATOM   2174  C CA  . LEU A 1 431 ? 135.315 143.451 138.001 1.00 25.54  ? 431  LEU A CA  1 
ATOM   2175  C C   . LEU A 1 431 ? 134.624 144.720 137.545 1.00 25.54  ? 431  LEU A C   1 
ATOM   2176  O O   . LEU A 1 431 ? 133.631 144.642 136.818 1.00 25.54  ? 431  LEU A O   1 
ATOM   2177  C CB  . LEU A 1 431 ? 134.320 142.591 138.769 1.00 25.54  ? 431  LEU A CB  1 
ATOM   2178  C CG  . LEU A 1 431 ? 134.581 141.097 138.693 1.00 25.54  ? 431  LEU A CG  1 
ATOM   2179  C CD1 . LEU A 1 431 ? 133.629 140.384 139.612 1.00 25.54  ? 431  LEU A CD1 1 
ATOM   2180  C CD2 . LEU A 1 431 ? 134.406 140.624 137.270 1.00 25.54  ? 431  LEU A CD2 1 
ATOM   2181  N N   . SER A 1 432 ? 135.105 145.881 137.975 1.00 21.29  ? 432  SER A N   1 
ATOM   2182  C CA  . SER A 1 432 ? 134.689 147.129 137.354 1.00 21.29  ? 432  SER A CA  1 
ATOM   2183  C C   . SER A 1 432 ? 135.593 147.483 136.180 1.00 21.29  ? 432  SER A C   1 
ATOM   2184  O O   . SER A 1 432 ? 135.107 147.788 135.091 1.00 21.29  ? 432  SER A O   1 
ATOM   2185  C CB  . SER A 1 432 ? 134.685 148.248 138.392 1.00 21.29  ? 432  SER A CB  1 
ATOM   2186  O OG  . SER A 1 432 ? 134.762 149.523 137.781 1.00 21.29  ? 432  SER A OG  1 
ATOM   2187  N N   . MET A 1 433 ? 136.908 147.404 136.376 1.00 35.55  ? 433  MET A N   1 
ATOM   2188  C CA  . MET A 1 433 ? 137.856 147.750 135.328 1.00 35.55  ? 433  MET A CA  1 
ATOM   2189  C C   . MET A 1 433 ? 137.854 146.742 134.188 1.00 35.55  ? 433  MET A C   1 
ATOM   2190  O O   . MET A 1 433 ? 138.355 147.036 133.101 1.00 35.55  ? 433  MET A O   1 
ATOM   2191  C CB  . MET A 1 433 ? 139.246 147.860 135.928 1.00 35.55  ? 433  MET A CB  1 
ATOM   2192  C CG  . MET A 1 433 ? 140.198 148.660 135.119 1.00 35.55  ? 433  MET A CG  1 
ATOM   2193  S SD  . MET A 1 433 ? 141.306 147.591 134.238 1.00 35.55  ? 433  MET A SD  1 
ATOM   2194  C CE  . MET A 1 433 ? 142.220 147.023 135.634 1.00 35.55  ? 433  MET A CE  1 
ATOM   2195  N N   . PHE A 1 434 ? 137.292 145.562 134.387 1.00 24.61  ? 434  PHE A N   1 
ATOM   2196  C CA  . PHE A 1 434 ? 137.244 144.595 133.306 1.00 24.61  ? 434  PHE A CA  1 
ATOM   2197  C C   . PHE A 1 434 ? 135.868 144.466 132.684 1.00 24.61  ? 434  PHE A C   1 
ATOM   2198  O O   . PHE A 1 434 ? 135.742 143.852 131.626 1.00 24.61  ? 434  PHE A O   1 
ATOM   2199  C CB  . PHE A 1 434 ? 137.711 143.233 133.798 1.00 24.61  ? 434  PHE A CB  1 
ATOM   2200  C CG  . PHE A 1 434 ? 139.189 143.057 133.753 1.00 24.61  ? 434  PHE A CG  1 
ATOM   2201  C CD1 . PHE A 1 434 ? 139.893 143.349 132.604 1.00 24.61  ? 434  PHE A CD1 1 
ATOM   2202  C CD2 . PHE A 1 434 ? 139.869 142.572 134.852 1.00 24.61  ? 434  PHE A CD2 1 
ATOM   2203  C CE1 . PHE A 1 434 ? 141.248 143.181 132.556 1.00 24.61  ? 434  PHE A CE1 1 
ATOM   2204  C CE2 . PHE A 1 434 ? 141.223 142.405 134.811 1.00 24.61  ? 434  PHE A CE2 1 
ATOM   2205  C CZ  . PHE A 1 434 ? 141.913 142.710 133.659 1.00 24.61  ? 434  PHE A CZ  1 
ATOM   2206  N N   . GLY A 1 435 ? 134.842 145.014 133.308 1.00 35.55  ? 435  GLY A N   1 
ATOM   2207  C CA  . GLY A 1 435 ? 133.558 145.066 132.657 1.00 35.55  ? 435  GLY A CA  1 
ATOM   2208  C C   . GLY A 1 435 ? 133.373 146.263 131.778 1.00 35.55  ? 435  GLY A C   1 
ATOM   2209  O O   . GLY A 1 435 ? 132.430 146.296 130.987 1.00 35.55  ? 435  GLY A O   1 
ATOM   2210  N N   . LEU A 1 436 ? 134.252 147.258 131.905 1.00 16.44  ? 436  LEU A N   1 
ATOM   2211  C CA  . LEU A 1 436 ? 134.257 148.455 131.075 1.00 16.44  ? 436  LEU A CA  1 
ATOM   2212  C C   . LEU A 1 436 ? 135.221 148.355 129.909 1.00 16.44  ? 436  LEU A C   1 
ATOM   2213  O O   . LEU A 1 436 ? 134.908 148.825 128.818 1.00 16.44  ? 436  LEU A O   1 
ATOM   2214  C CB  . LEU A 1 436 ? 134.616 149.683 131.909 1.00 16.44  ? 436  LEU A CB  1 
ATOM   2215  C CG  . LEU A 1 436 ? 133.718 149.993 133.096 1.00 16.44  ? 436  LEU A CG  1 
ATOM   2216  C CD1 . LEU A 1 436 ? 134.198 151.222 133.801 1.00 16.44  ? 436  LEU A CD1 1 
ATOM   2217  C CD2 . LEU A 1 436 ? 132.321 150.179 132.631 1.00 16.44  ? 436  LEU A CD2 1 
ATOM   2218  N N   . LEU A 1 437 ? 136.388 147.751 130.115 1.00 22.56  ? 437  LEU A N   1 
ATOM   2219  C CA  . LEU A 1 437 ? 137.333 147.569 129.024 1.00 22.56  ? 437  LEU A CA  1 
ATOM   2220  C C   . LEU A 1 437 ? 136.857 146.521 128.024 1.00 22.56  ? 437  LEU A C   1 
ATOM   2221  O O   . LEU A 1 437 ? 137.100 146.660 126.824 1.00 22.56  ? 437  LEU A O   1 
ATOM   2222  C CB  . LEU A 1 437 ? 138.689 147.202 129.596 1.00 22.56  ? 437  LEU A CB  1 
ATOM   2223  C CG  . LEU A 1 437 ? 139.806 146.888 128.615 1.00 22.56  ? 437  LEU A CG  1 
ATOM   2224  C CD1 . LEU A 1 437 ? 140.031 148.031 127.659 1.00 22.56  ? 437  LEU A CD1 1 
ATOM   2225  C CD2 . LEU A 1 437 ? 141.073 146.583 129.368 1.00 22.56  ? 437  LEU A CD2 1 
ATOM   2226  N N   . PHE A 1 438 ? 136.158 145.484 128.481 1.00 35.55  ? 438  PHE A N   1 
ATOM   2227  C CA  . PHE A 1 438 ? 135.639 144.452 127.597 1.00 35.55  ? 438  PHE A CA  1 
ATOM   2228  C C   . PHE A 1 438 ? 134.200 144.697 127.204 1.00 35.55  ? 438  PHE A C   1 
ATOM   2229  O O   . PHE A 1 438 ? 133.566 143.815 126.629 1.00 35.55  ? 438  PHE A O   1 
ATOM   2230  C CB  . PHE A 1 438 ? 135.787 143.077 128.236 1.00 35.55  ? 438  PHE A CB  1 
ATOM   2231  C CG  . PHE A 1 438 ? 137.189 142.601 128.280 1.00 35.55  ? 438  PHE A CG  1 
ATOM   2232  C CD1 . PHE A 1 438 ? 137.920 142.495 127.120 1.00 35.55  ? 438  PHE A CD1 1 
ATOM   2233  C CD2 . PHE A 1 438 ? 137.787 142.290 129.473 1.00 35.55  ? 438  PHE A CD2 1 
ATOM   2234  C CE1 . PHE A 1 438 ? 139.212 142.080 127.150 1.00 35.55  ? 438  PHE A CE1 1 
ATOM   2235  C CE2 . PHE A 1 438 ? 139.077 141.878 129.503 1.00 35.55  ? 438  PHE A CE2 1 
ATOM   2236  C CZ  . PHE A 1 438 ? 139.790 141.774 128.339 1.00 35.55  ? 438  PHE A CZ  1 
ATOM   2237  N N   . LEU A 1 439 ? 133.659 145.860 127.527 1.00 24.59  ? 439  LEU A N   1 
ATOM   2238  C CA  . LEU A 1 439 ? 132.492 146.363 126.828 1.00 24.59  ? 439  LEU A CA  1 
ATOM   2239  C C   . LEU A 1 439 ? 132.876 147.260 125.666 1.00 24.59  ? 439  LEU A C   1 
ATOM   2240  O O   . LEU A 1 439 ? 132.146 147.311 124.675 1.00 24.59  ? 439  LEU A O   1 
ATOM   2241  C CB  . LEU A 1 439 ? 131.582 147.135 127.786 1.00 24.59  ? 439  LEU A CB  1 
ATOM   2242  C CG  . LEU A 1 439 ? 130.236 147.619 127.265 1.00 24.59  ? 439  LEU A CG  1 
ATOM   2243  C CD1 . LEU A 1 439 ? 129.499 146.476 126.643 1.00 24.59  ? 439  LEU A CD1 1 
ATOM   2244  C CD2 . LEU A 1 439 ? 129.433 148.226 128.369 1.00 24.59  ? 439  LEU A CD2 1 
ATOM   2245  N N   . HIS A 1 440 ? 134.019 147.937 125.742 1.00 35.55  ? 440  HIS A N   1 
ATOM   2246  C CA  . HIS A 1 440 ? 134.467 148.771 124.644 1.00 35.55  ? 440  HIS A CA  1 
ATOM   2247  C C   . HIS A 1 440 ? 135.026 147.978 123.481 1.00 35.55  ? 440  HIS A C   1 
ATOM   2248  O O   . HIS A 1 440 ? 134.726 148.309 122.333 1.00 35.55  ? 440  HIS A O   1 
ATOM   2249  C CB  . HIS A 1 440 ? 135.521 149.758 125.106 1.00 35.55  ? 440  HIS A CB  1 
ATOM   2250  C CG  . HIS A 1 440 ? 135.539 151.011 124.300 1.00 35.55  ? 440  HIS A CG  1 
ATOM   2251  N ND1 . HIS A 1 440 ? 136.203 152.146 124.699 1.00 35.55  ? 440  HIS A ND1 1 
ATOM   2252  C CD2 . HIS A 1 440 ? 134.958 151.310 123.117 1.00 35.55  ? 440  HIS A CD2 1 
ATOM   2253  C CE1 . HIS A 1 440 ? 136.026 153.092 123.800 1.00 35.55  ? 440  HIS A CE1 1 
ATOM   2254  N NE2 . HIS A 1 440 ? 135.283 152.607 122.824 1.00 35.55  ? 440  HIS A NE2 1 
ATOM   2255  N N   . LEU A 1 441 ? 135.833 146.957 123.739 1.00 28.89  ? 441  LEU A N   1 
ATOM   2256  C CA  . LEU A 1 441 ? 136.317 146.072 122.694 1.00 28.89  ? 441  LEU A CA  1 
ATOM   2257  C C   . LEU A 1 441 ? 135.198 145.316 122.006 1.00 28.89  ? 441  LEU A C   1 
ATOM   2258  O O   . LEU A 1 441 ? 135.319 145.009 120.825 1.00 28.89  ? 441  LEU A O   1 
ATOM   2259  C CB  . LEU A 1 441 ? 137.330 145.088 123.280 1.00 28.89  ? 441  LEU A CB  1 
ATOM   2260  C CG  . LEU A 1 441 ? 137.962 144.015 122.407 1.00 28.89  ? 441  LEU A CG  1 
ATOM   2261  C CD1 . LEU A 1 441 ? 138.744 144.649 121.289 1.00 28.89  ? 441  LEU A CD1 1 
ATOM   2262  C CD2 . LEU A 1 441 ? 138.844 143.134 123.253 1.00 28.89  ? 441  LEU A CD2 1 
ATOM   2263  N N   . PHE A 1 442 ? 134.103 145.046 122.697 1.00 35.55  ? 442  PHE A N   1 
ATOM   2264  C CA  . PHE A 1 442 ? 132.937 144.484 122.045 1.00 35.55  ? 442  PHE A CA  1 
ATOM   2265  C C   . PHE A 1 442 ? 132.270 145.491 121.128 1.00 35.55  ? 442  PHE A C   1 
ATOM   2266  O O   . PHE A 1 442 ? 131.936 145.152 119.993 1.00 35.55  ? 442  PHE A O   1 
ATOM   2267  C CB  . PHE A 1 442 ? 131.944 143.987 123.085 1.00 35.55  ? 442  PHE A CB  1 
ATOM   2268  C CG  . PHE A 1 442 ? 130.600 143.681 122.537 1.00 35.55  ? 442  PHE A CG  1 
ATOM   2269  C CD1 . PHE A 1 442 ? 129.524 144.476 122.842 1.00 35.55  ? 442  PHE A CD1 1 
ATOM   2270  C CD2 . PHE A 1 442 ? 130.403 142.589 121.734 1.00 35.55  ? 442  PHE A CD2 1 
ATOM   2271  C CE1 . PHE A 1 442 ? 128.277 144.202 122.337 1.00 35.55  ? 442  PHE A CE1 1 
ATOM   2272  C CE2 . PHE A 1 442 ? 129.154 142.308 121.229 1.00 35.55  ? 442  PHE A CE2 1 
ATOM   2273  C CZ  . PHE A 1 442 ? 128.094 143.117 121.529 1.00 35.55  ? 442  PHE A CZ  1 
ATOM   2274  N N   . LEU A 1 443 ? 132.087 146.736 121.573 1.00 22.23  ? 443  LEU A N   1 
ATOM   2275  C CA  . LEU A 1 443 ? 131.459 147.754 120.732 1.00 22.23  ? 443  LEU A CA  1 
ATOM   2276  C C   . LEU A 1 443 ? 132.369 148.263 119.630 1.00 22.23  ? 443  LEU A C   1 
ATOM   2277  O O   . LEU A 1 443 ? 131.889 148.955 118.734 1.00 22.23  ? 443  LEU A O   1 
ATOM   2278  C CB  . LEU A 1 443 ? 130.989 148.935 121.571 1.00 22.23  ? 443  LEU A CB  1 
ATOM   2279  C CG  . LEU A 1 443 ? 129.886 148.592 122.545 1.00 22.23  ? 443  LEU A CG  1 
ATOM   2280  C CD1 . LEU A 1 443 ? 129.911 149.564 123.639 1.00 22.23  ? 443  LEU A CD1 1 
ATOM   2281  C CD2 . LEU A 1 443 ? 128.581 148.658 121.851 1.00 22.23  ? 443  LEU A CD2 1 
ATOM   2282  N N   . TYR A 1 444 ? 133.658 147.965 119.679 1.00 18.77  ? 444  TYR A N   1 
ATOM   2283  C CA  . TYR A 1 444 ? 134.524 148.103 118.524 1.00 18.77  ? 444  TYR A CA  1 
ATOM   2284  C C   . TYR A 1 444 ? 134.308 146.975 117.528 1.00 18.77  ? 444  TYR A C   1 
ATOM   2285  O O   . TYR A 1 444 ? 134.662 147.105 116.359 1.00 18.77  ? 444  TYR A O   1 
ATOM   2286  C CB  . TYR A 1 444 ? 135.978 148.145 118.980 1.00 18.77  ? 444  TYR A CB  1 
ATOM   2287  C CG  . TYR A 1 444 ? 136.974 148.313 117.875 1.00 18.77  ? 444  TYR A CG  1 
ATOM   2288  C CD1 . TYR A 1 444 ? 138.077 147.485 117.790 1.00 18.77  ? 444  TYR A CD1 1 
ATOM   2289  C CD2 . TYR A 1 444 ? 136.817 149.299 116.916 1.00 18.77  ? 444  TYR A CD2 1 
ATOM   2290  C CE1 . TYR A 1 444 ? 138.997 147.630 116.778 1.00 18.77  ? 444  TYR A CE1 1 
ATOM   2291  C CE2 . TYR A 1 444 ? 137.727 149.450 115.895 1.00 18.77  ? 444  TYR A CE2 1 
ATOM   2292  C CZ  . TYR A 1 444 ? 138.817 148.615 115.835 1.00 18.77  ? 444  TYR A CZ  1 
ATOM   2293  O OH  . TYR A 1 444 ? 139.732 148.767 114.826 1.00 18.77  ? 444  TYR A OH  1 
ATOM   2294  N N   . GLY A 1 445 ? 133.689 145.889 117.951 1.00 15.92  ? 445  GLY A N   1 
ATOM   2295  C CA  . GLY A 1 445 ? 133.448 144.795 117.053 1.00 15.92  ? 445  GLY A CA  1 
ATOM   2296  C C   . GLY A 1 445 ? 132.004 144.746 116.659 1.00 15.92  ? 445  GLY A C   1 
ATOM   2297  O O   . GLY A 1 445 ? 131.605 143.947 115.815 1.00 15.92  ? 445  GLY A O   1 
ATOM   2298  N N   . CYS A 1 446 ? 131.201 145.580 117.288 1.00 15.15  ? 446  CYS A N   1 
ATOM   2299  C CA  . CYS A 1 446 ? 129.855 145.812 116.813 1.00 15.15  ? 446  CYS A CA  1 
ATOM   2300  C C   . CYS A 1 446 ? 129.814 147.037 115.915 1.00 15.15  ? 446  CYS A C   1 
ATOM   2301  O O   . CYS A 1 446 ? 128.741 147.439 115.463 1.00 15.15  ? 446  CYS A O   1 
ATOM   2302  C CB  . CYS A 1 446 ? 128.912 145.946 118.005 1.00 15.15  ? 446  CYS A CB  1 
ATOM   2303  S SG  . CYS A 1 446 ? 127.153 145.787 117.659 1.00 15.15  ? 446  CYS A SG  1 
ATOM   2304  N N   . ASN A 1 447 ? 130.977 147.636 115.650 1.00 16.66  ? 447  ASN A N   1 
ATOM   2305  C CA  . ASN A 1 447 ? 131.126 148.729 114.704 1.00 16.66  ? 447  ASN A CA  1 
ATOM   2306  C C   . ASN A 1 447 ? 131.858 148.330 113.440 1.00 16.66  ? 447  ASN A C   1 
ATOM   2307  O O   . ASN A 1 447 ? 131.662 148.978 112.416 1.00 16.66  ? 447  ASN A O   1 
ATOM   2308  C CB  . ASN A 1 447 ? 131.863 149.907 115.345 1.00 16.66  ? 447  ASN A CB  1 
ATOM   2309  C CG  . ASN A 1 447 ? 130.959 150.743 116.202 1.00 16.66  ? 447  ASN A CG  1 
ATOM   2310  O OD1 . ASN A 1 447 ? 129.744 150.722 116.037 1.00 16.66  ? 447  ASN A OD1 1 
ATOM   2311  N ND2 . ASN A 1 447 ? 131.540 151.479 117.129 1.00 16.66  ? 447  ASN A ND2 1 
ATOM   2312  N N   . ILE A 1 448 ? 132.685 147.287 113.471 1.00 16.44  ? 448  ILE A N   1 
ATOM   2313  C CA  . ILE A 1 448 ? 133.145 146.669 112.238 1.00 16.44  ? 448  ILE A CA  1 
ATOM   2314  C C   . ILE A 1 448 ? 132.021 145.900 111.564 1.00 16.44  ? 448  ILE A C   1 
ATOM   2315  O O   . ILE A 1 448 ? 131.965 145.849 110.343 1.00 16.44  ? 448  ILE A O   1 
ATOM   2316  C CB  . ILE A 1 448 ? 134.378 145.780 112.466 1.00 16.44  ? 448  ILE A CB  1 
ATOM   2317  C CG1 . ILE A 1 448 ? 135.434 146.539 113.256 1.00 16.44  ? 448  ILE A CG1 1 
ATOM   2318  C CG2 . ILE A 1 448 ? 135.020 145.391 111.159 1.00 16.44  ? 448  ILE A CG2 1 
ATOM   2319  C CD1 . ILE A 1 448 ? 136.729 145.784 113.470 1.00 16.44  ? 448  ILE A CD1 1 
ATOM   2320  N N   . PHE A 1 449 ? 131.069 145.385 112.325 1.00 17.09  ? 449  PHE A N   1 
ATOM   2321  C CA  . PHE A 1 449 ? 129.881 144.816 111.717 1.00 17.09  ? 449  PHE A CA  1 
ATOM   2322  C C   . PHE A 1 449 ? 128.992 145.870 111.076 1.00 17.09  ? 449  PHE A C   1 
ATOM   2323  O O   . PHE A 1 449 ? 128.264 145.548 110.139 1.00 17.09  ? 449  PHE A O   1 
ATOM   2324  C CB  . PHE A 1 449 ? 129.074 144.019 112.747 1.00 17.09  ? 449  PHE A CB  1 
ATOM   2325  C CG  . PHE A 1 449 ? 127.797 143.445 112.208 1.00 17.09  ? 449  PHE A CG  1 
ATOM   2326  C CD1 . PHE A 1 449 ? 126.578 143.992 112.552 1.00 17.09  ? 449  PHE A CD1 1 
ATOM   2327  C CD2 . PHE A 1 449 ? 127.818 142.381 111.335 1.00 17.09  ? 449  PHE A CD2 1 
ATOM   2328  C CE1 . PHE A 1 449 ? 125.403 143.476 112.045 1.00 17.09  ? 449  PHE A CE1 1 
ATOM   2329  C CE2 . PHE A 1 449 ? 126.646 141.858 110.829 1.00 17.09  ? 449  PHE A CE2 1 
ATOM   2330  C CZ  . PHE A 1 449 ? 125.439 142.408 111.186 1.00 17.09  ? 449  PHE A CZ  1 
ATOM   2331  N N   . MET A 1 450 ? 129.064 147.128 111.506 1.00 24.36  ? 450  MET A N   1 
ATOM   2332  C CA  . MET A 1 450 ? 128.300 148.179 110.852 1.00 24.36  ? 450  MET A CA  1 
ATOM   2333  C C   . MET A 1 450 ? 129.102 148.984 109.845 1.00 24.36  ? 450  MET A C   1 
ATOM   2334  O O   . MET A 1 450 ? 128.500 149.671 109.020 1.00 24.36  ? 450  MET A O   1 
ATOM   2335  C CB  . MET A 1 450 ? 127.708 149.142 111.886 1.00 24.36  ? 450  MET A CB  1 
ATOM   2336  C CG  . MET A 1 450 ? 126.697 148.518 112.816 1.00 24.36  ? 450  MET A CG  1 
ATOM   2337  S SD  . MET A 1 450 ? 126.426 149.528 114.276 1.00 24.36  ? 450  MET A SD  1 
ATOM   2338  C CE  . MET A 1 450 ? 125.055 148.646 114.995 1.00 24.36  ? 450  MET A CE  1 
ATOM   2339  N N   . TRP A 1 451 ? 130.433 148.917 109.888 1.00 22.32  ? 451  TRP A N   1 
ATOM   2340  C CA  . TRP A 1 451 ? 131.252 149.542 108.856 1.00 22.32  ? 451  TRP A CA  1 
ATOM   2341  C C   . TRP A 1 451 ? 131.300 148.695 107.595 1.00 22.32  ? 451  TRP A C   1 
ATOM   2342  O O   . TRP A 1 451 ? 131.201 149.227 106.485 1.00 22.32  ? 451  TRP A O   1 
ATOM   2343  C CB  . TRP A 1 451 ? 132.665 149.789 109.376 1.00 22.32  ? 451  TRP A CB  1 
ATOM   2344  C CG  . TRP A 1 451 ? 132.725 150.946 110.294 1.00 22.32  ? 451  TRP A CG  1 
ATOM   2345  C CD1 . TRP A 1 451 ? 131.795 151.914 110.428 1.00 22.32  ? 451  TRP A CD1 1 
ATOM   2346  C CD2 . TRP A 1 451 ? 133.758 151.251 111.230 1.00 22.32  ? 451  TRP A CD2 1 
ATOM   2347  N NE1 . TRP A 1 451 ? 132.184 152.817 111.378 1.00 22.32  ? 451  TRP A NE1 1 
ATOM   2348  C CE2 . TRP A 1 451 ? 133.391 152.426 111.884 1.00 22.32  ? 451  TRP A CE2 1 
ATOM   2349  C CE3 . TRP A 1 451 ? 134.956 150.640 111.581 1.00 22.32  ? 451  TRP A CE3 1 
ATOM   2350  C CZ2 . TRP A 1 451 ? 134.179 153.003 112.853 1.00 22.32  ? 451  TRP A CZ2 1 
ATOM   2351  C CZ3 . TRP A 1 451 ? 135.741 151.223 112.538 1.00 22.32  ? 451  TRP A CZ3 1 
ATOM   2352  C CH2 . TRP A 1 451 ? 135.351 152.384 113.165 1.00 22.32  ? 451  TRP A CH2 1 
ATOM   2353  N N   . ARG A 1 452 ? 131.466 147.381 107.748 1.00 26.19  ? 452  ARG A N   1 
ATOM   2354  C CA  . ARG A 1 452 ? 131.448 146.489 106.598 1.00 26.19  ? 452  ARG A CA  1 
ATOM   2355  C C   . ARG A 1 452 ? 130.078 146.465 105.945 1.00 26.19  ? 452  ARG A C   1 
ATOM   2356  O O   . ARG A 1 452 ? 129.976 146.426 104.717 1.00 26.19  ? 452  ARG A O   1 
ATOM   2357  C CB  . ARG A 1 452 ? 131.855 145.081 107.018 1.00 26.19  ? 452  ARG A CB  1 
ATOM   2358  C CG  . ARG A 1 452 ? 133.267 144.966 107.558 1.00 26.19  ? 452  ARG A CG  1 
ATOM   2359  C CD  . ARG A 1 452 ? 134.309 145.058 106.479 1.00 26.19  ? 452  ARG A CD  1 
ATOM   2360  N NE  . ARG A 1 452 ? 135.552 144.407 106.876 1.00 26.19  ? 452  ARG A NE  1 
ATOM   2361  C CZ  . ARG A 1 452 ? 135.775 143.102 106.779 1.00 26.19  ? 452  ARG A CZ  1 
ATOM   2362  N NH1 . ARG A 1 452 ? 134.838 142.298 106.300 1.00 26.19  ? 452  ARG A NH1 1 
ATOM   2363  N NH2 . ARG A 1 452 ? 136.939 142.597 107.158 1.00 26.19  ? 452  ARG A NH2 1 
ATOM   2364  N N   . LYS A 1 453 ? 129.013 146.534 106.739 1.00 23.39  ? 453  LYS A N   1 
ATOM   2365  C CA  . LYS A 1 453 ? 127.661 146.412 106.214 1.00 23.39  ? 453  LYS A CA  1 
ATOM   2366  C C   . LYS A 1 453 ? 127.142 147.715 105.616 1.00 23.39  ? 453  LYS A C   1 
ATOM   2367  O O   . LYS A 1 453 ? 125.983 147.785 105.197 1.00 23.39  ? 453  LYS A O   1 
ATOM   2368  C CB  . LYS A 1 453 ? 126.709 145.911 107.294 1.00 23.39  ? 453  LYS A CB  1 
ATOM   2369  C CG  . LYS A 1 453 ? 125.675 144.935 106.784 1.00 23.39  ? 453  LYS A CG  1 
ATOM   2370  C CD  . LYS A 1 453 ? 124.693 144.576 107.863 1.00 23.39  ? 453  LYS A CD  1 
ATOM   2371  C CE  . LYS A 1 453 ? 123.815 145.765 108.200 1.00 23.39  ? 453  LYS A CE  1 
ATOM   2372  N NZ  . LYS A 1 453 ? 122.926 146.119 107.063 1.00 23.39  ? 453  LYS A NZ  1 
ATOM   2373  N N   . ALA A 1 454 ? 127.964 148.757 105.579 1.00 27.50  ? 454  ALA A N   1 
ATOM   2374  C CA  . ALA A 1 454 ? 127.661 149.921 104.763 1.00 27.50  ? 454  ALA A CA  1 
ATOM   2375  C C   . ALA A 1 454 ? 128.846 150.360 103.925 1.00 27.50  ? 454  ALA A C   1 
ATOM   2376  O O   . ALA A 1 454 ? 128.749 151.394 103.260 1.00 27.50  ? 454  ALA A O   1 
ATOM   2377  C CB  . ALA A 1 454 ? 127.186 151.092 105.628 1.00 27.50  ? 454  ALA A CB  1 
ATOM   2378  N N   . ARG A 1 455 ? 129.952 149.610 103.955 1.00 36.15  ? 455  ARG A N   1 
ATOM   2379  C CA  . ARG A 1 455 ? 131.139 149.779 103.112 1.00 36.15  ? 455  ARG A CA  1 
ATOM   2380  C C   . ARG A 1 455 ? 131.793 151.142 103.355 1.00 36.15  ? 455  ARG A C   1 
ATOM   2381  O O   . ARG A 1 455 ? 132.028 151.933 102.446 1.00 36.15  ? 455  ARG A O   1 
ATOM   2382  C CB  . ARG A 1 455 ? 130.798 149.559 101.629 1.00 36.15  ? 455  ARG A CB  1 
ATOM   2383  C CG  . ARG A 1 455 ? 130.189 148.191 101.330 1.00 36.15  ? 455  ARG A CG  1 
ATOM   2384  C CD  . ARG A 1 455 ? 129.425 148.182 100.021 1.00 36.15  ? 455  ARG A CD  1 
ATOM   2385  N NE  . ARG A 1 455 ? 128.219 149.002 100.063 1.00 36.15  ? 455  ARG A NE  1 
ATOM   2386  C CZ  . ARG A 1 455 ? 126.995 148.519 100.251 1.00 36.15  ? 455  ARG A CZ  1 
ATOM   2387  N NH1 . ARG A 1 455 ? 126.814 147.216 100.412 1.00 36.15  ? 455  ARG A NH1 1 
ATOM   2388  N NH2 . ARG A 1 455 ? 125.950 149.334 100.272 1.00 36.15  ? 455  ARG A NH2 1 
ATOM   2389  N N   . ILE A 1 456 ? 132.114 151.372 104.622 1.00 25.56  ? 456  ILE A N   1 
ATOM   2390  C CA  . ILE A 1 456 ? 132.576 152.680 105.066 1.00 25.56  ? 456  ILE A CA  1 
ATOM   2391  C C   . ILE A 1 456 ? 134.104 152.693 105.037 1.00 25.56  ? 456  ILE A C   1 
ATOM   2392  O O   . ILE A 1 456 ? 134.736 153.720 105.318 1.00 25.56  ? 456  ILE A O   1 
ATOM   2393  C CB  . ILE A 1 456 ? 131.946 153.000 106.437 1.00 25.56  ? 456  ILE A CB  1 
ATOM   2394  C CG1 . ILE A 1 456 ? 130.437 152.795 106.303 1.00 25.56  ? 456  ILE A CG1 1 
ATOM   2395  C CG2 . ILE A 1 456 ? 132.142 154.431 106.859 1.00 25.56  ? 456  ILE A CG2 1 
ATOM   2396  C CD1 . ILE A 1 456 ? 129.548 153.431 107.375 1.00 25.56  ? 456  ILE A CD1 1 
ATOM   2397  N N   . ASN A 1 457 ? 134.696 151.576 104.603 1.00 27.58  ? 457  ASN A N   1 
ATOM   2398  C CA  . ASN A 1 457 ? 136.117 151.466 104.236 1.00 27.58  ? 457  ASN A CA  1 
ATOM   2399  C C   . ASN A 1 457 ? 137.029 151.886 105.393 1.00 27.58  ? 457  ASN A C   1 
ATOM   2400  O O   . ASN A 1 457 ? 137.674 152.933 105.390 1.00 27.58  ? 457  ASN A O   1 
ATOM   2401  C CB  . ASN A 1 457 ? 136.408 152.261 102.961 1.00 27.58  ? 457  ASN A CB  1 
ATOM   2402  C CG  . ASN A 1 457 ? 137.855 152.181 102.534 1.00 27.58  ? 457  ASN A CG  1 
ATOM   2403  O OD1 . ASN A 1 457 ? 138.533 151.188 102.775 1.00 27.58  ? 457  ASN A OD1 1 
ATOM   2404  N ND2 . ASN A 1 457 ? 138.348 153.255 101.941 1.00 27.58  ? 457  ASN A ND2 1 
ATOM   2405  N N   . TYR A 1 458 ? 137.004 151.079 106.440 1.00 28.93  ? 458  TYR A N   1 
ATOM   2406  C CA  . TYR A 1 458 ? 137.700 151.489 107.642 1.00 28.93  ? 458  TYR A CA  1 
ATOM   2407  C C   . TYR A 1 458 ? 139.192 151.233 107.564 1.00 28.93  ? 458  TYR A C   1 
ATOM   2408  O O   . TYR A 1 458 ? 139.946 151.848 108.319 1.00 28.93  ? 458  TYR A O   1 
ATOM   2409  C CB  . TYR A 1 458 ? 137.083 150.793 108.843 1.00 28.93  ? 458  TYR A CB  1 
ATOM   2410  C CG  . TYR A 1 458 ? 137.531 149.380 109.090 1.00 28.93  ? 458  TYR A CG  1 
ATOM   2411  C CD1 . TYR A 1 458 ? 137.026 148.335 108.342 1.00 28.93  ? 458  TYR A CD1 1 
ATOM   2412  C CD2 . TYR A 1 458 ? 138.434 149.089 110.102 1.00 28.93  ? 458  TYR A CD2 1 
ATOM   2413  C CE1 . TYR A 1 458 ? 137.432 147.042 108.576 1.00 28.93  ? 458  TYR A CE1 1 
ATOM   2414  C CE2 . TYR A 1 458 ? 138.840 147.805 110.345 1.00 28.93  ? 458  TYR A CE2 1 
ATOM   2415  C CZ  . TYR A 1 458 ? 138.341 146.787 109.581 1.00 28.93  ? 458  TYR A CZ  1 
ATOM   2416  O OH  . TYR A 1 458 ? 138.752 145.501 109.827 1.00 28.93  ? 458  TYR A OH  1 
ATOM   2417  N N   . SER A 1 459 ? 139.637 150.362 106.659 1.00 31.25  ? 459  SER A N   1 
ATOM   2418  C CA  . SER A 1 459 ? 141.050 150.002 106.617 1.00 31.25  ? 459  SER A CA  1 
ATOM   2419  C C   . SER A 1 459 ? 141.896 151.083 105.963 1.00 31.25  ? 459  SER A C   1 
ATOM   2420  O O   . SER A 1 459 ? 143.042 151.301 106.373 1.00 31.25  ? 459  SER A O   1 
ATOM   2421  C CB  . SER A 1 459 ? 141.232 148.679 105.879 1.00 31.25  ? 459  SER A CB  1 
ATOM   2422  O OG  . SER A 1 459 ? 142.606 148.382 105.711 1.00 31.25  ? 459  SER A OG  1 
ATOM   2423  N N   . PHE A 1 460 ? 141.362 151.763 104.950 1.00 31.17  ? 460  PHE A N   1 
ATOM   2424  C CA  . PHE A 1 460 ? 142.126 152.794 104.263 1.00 31.17  ? 460  PHE A CA  1 
ATOM   2425  C C   . PHE A 1 460 ? 142.120 154.115 105.022 1.00 31.17  ? 460  PHE A C   1 
ATOM   2426  O O   . PHE A 1 460 ? 143.144 154.806 105.050 1.00 31.17  ? 460  PHE A O   1 
ATOM   2427  C CB  . PHE A 1 460 ? 141.586 152.991 102.846 1.00 31.17  ? 460  PHE A CB  1 
ATOM   2428  C CG  . PHE A 1 460 ? 142.042 154.261 102.196 1.00 31.17  ? 460  PHE A CG  1 
ATOM   2429  C CD1 . PHE A 1 460 ? 143.378 154.456 101.888 1.00 31.17  ? 460  PHE A CD1 1 
ATOM   2430  C CD2 . PHE A 1 460 ? 141.135 155.261 101.893 1.00 31.17  ? 460  PHE A CD2 1 
ATOM   2431  C CE1 . PHE A 1 460 ? 143.800 155.626 101.300 1.00 31.17  ? 460  PHE A CE1 1 
ATOM   2432  C CE2 . PHE A 1 460 ? 141.551 156.430 101.305 1.00 31.17  ? 460  PHE A CE2 1 
ATOM   2433  C CZ  . PHE A 1 460 ? 142.886 156.611 101.003 1.00 31.17  ? 460  PHE A CZ  1 
ATOM   2434  N N   . ILE A 1 461 ? 140.981 154.476 105.627 1.00 26.52  ? 461  ILE A N   1 
ATOM   2435  C CA  . ILE A 1 461 ? 140.896 155.694 106.431 1.00 26.52  ? 461  ILE A CA  1 
ATOM   2436  C C   . ILE A 1 461 ? 141.833 155.610 107.622 1.00 26.52  ? 461  ILE A C   1 
ATOM   2437  O O   . ILE A 1 461 ? 142.620 156.528 107.873 1.00 26.52  ? 461  ILE A O   1 
ATOM   2438  C CB  . ILE A 1 461 ? 139.449 155.943 106.881 1.00 26.52  ? 461  ILE A CB  1 
ATOM   2439  C CG1 . ILE A 1 461 ? 138.534 156.122 105.682 1.00 26.52  ? 461  ILE A CG1 1 
ATOM   2440  C CG2 . ILE A 1 461 ? 139.377 157.178 107.708 1.00 26.52  ? 461  ILE A CG2 1 
ATOM   2441  C CD1 . ILE A 1 461 ? 137.080 156.188 106.048 1.00 26.52  ? 461  ILE A CD1 1 
ATOM   2442  N N   . PHE A 1 462 ? 141.811 154.485 108.337 1.00 28.00  ? 462  PHE A N   1 
ATOM   2443  C CA  . PHE A 1 462 ? 142.719 154.258 109.454 1.00 28.00  ? 462  PHE A CA  1 
ATOM   2444  C C   . PHE A 1 462 ? 144.155 154.000 109.015 1.00 28.00  ? 462  PHE A C   1 
ATOM   2445  O O   . PHE A 1 462 ? 145.036 153.954 109.880 1.00 28.00  ? 462  PHE A O   1 
ATOM   2446  C CB  . PHE A 1 462 ? 142.250 153.069 110.301 1.00 28.00  ? 462  PHE A CB  1 
ATOM   2447  C CG  . PHE A 1 462 ? 140.931 153.278 111.014 1.00 28.00  ? 462  PHE A CG  1 
ATOM   2448  C CD1 . PHE A 1 462 ? 140.432 154.540 111.256 1.00 28.00  ? 462  PHE A CD1 1 
ATOM   2449  C CD2 . PHE A 1 462 ? 140.214 152.191 111.477 1.00 28.00  ? 462  PHE A CD2 1 
ATOM   2450  C CE1 . PHE A 1 462 ? 139.239 154.702 111.917 1.00 28.00  ? 462  PHE A CE1 1 
ATOM   2451  C CE2 . PHE A 1 462 ? 139.026 152.356 112.136 1.00 28.00  ? 462  PHE A CE2 1 
ATOM   2452  C CZ  . PHE A 1 462 ? 138.540 153.607 112.354 1.00 28.00  ? 462  PHE A CZ  1 
ATOM   2453  N N   . GLU A 1 463 ? 144.392 153.837 107.705 1.00 32.52  ? 463  GLU A N   1 
ATOM   2454  C CA  . GLU A 1 463 ? 145.670 153.437 107.101 1.00 32.52  ? 463  GLU A CA  1 
ATOM   2455  C C   . GLU A 1 463 ? 146.141 152.094 107.660 1.00 32.52  ? 463  GLU A C   1 
ATOM   2456  O O   . GLU A 1 463 ? 147.276 151.934 108.111 1.00 32.52  ? 463  GLU A O   1 
ATOM   2457  C CB  . GLU A 1 463 ? 146.754 154.514 107.264 1.00 32.52  ? 463  GLU A CB  1 
ATOM   2458  C CG  . GLU A 1 463 ? 146.553 155.753 106.415 1.00 32.52  ? 463  GLU A CG  1 
ATOM   2459  C CD  . GLU A 1 463 ? 145.643 156.752 107.085 1.00 32.52  ? 463  GLU A CD  1 
ATOM   2460  O OE1 . GLU A 1 463 ? 144.993 157.552 106.381 1.00 32.52  ? 463  GLU A OE1 1 
ATOM   2461  O OE2 . GLU A 1 463 ? 145.568 156.723 108.327 1.00 32.52  ? 463  GLU A OE2 1 
ATOM   2462  N N   . LEU A 1 464 ? 145.239 151.115 107.611 1.00 31.00  ? 464  LEU A N   1 
ATOM   2463  C CA  . LEU A 1 464 ? 145.536 149.819 108.206 1.00 31.00  ? 464  LEU A CA  1 
ATOM   2464  C C   . LEU A 1 464 ? 146.438 148.983 107.304 1.00 31.00  ? 464  LEU A C   1 
ATOM   2465  O O   . LEU A 1 464 ? 147.561 148.631 107.682 1.00 31.00  ? 464  LEU A O   1 
ATOM   2466  C CB  . LEU A 1 464 ? 144.236 149.073 108.503 1.00 31.00  ? 464  LEU A CB  1 
ATOM   2467  C CG  . LEU A 1 464 ? 143.517 149.475 109.781 1.00 31.00  ? 464  LEU A CG  1 
ATOM   2468  C CD1 . LEU A 1 464 ? 142.289 148.635 109.953 1.00 31.00  ? 464  LEU A CD1 1 
ATOM   2469  C CD2 . LEU A 1 464 ? 144.432 149.299 110.952 1.00 31.00  ? 464  LEU A CD2 1 
ATOM   2470  N N   . GLY A 1 465 ? 145.968 148.672 106.104 1.00 41.15  ? 465  GLY A N   1 
ATOM   2471  C CA  . GLY A 1 465 ? 146.623 147.725 105.225 1.00 41.15  ? 465  GLY A CA  1 
ATOM   2472  C C   . GLY A 1 465 ? 145.889 146.397 105.224 1.00 41.15  ? 465  GLY A C   1 
ATOM   2473  O O   . GLY A 1 465 ? 144.814 146.246 105.808 1.00 41.15  ? 465  GLY A O   1 
ATOM   2474  N N   . SER A 1 466 ? 146.490 145.422 104.541 1.00 44.87  ? 466  SER A N   1 
ATOM   2475  C CA  . SER A 1 466 ? 145.913 144.084 104.540 1.00 44.87  ? 466  SER A CA  1 
ATOM   2476  C C   . SER A 1 466 ? 146.161 143.438 105.896 1.00 44.87  ? 466  SER A C   1 
ATOM   2477  O O   . SER A 1 466 ? 145.208 143.237 106.655 1.00 44.87  ? 466  SER A O   1 
ATOM   2478  C CB  . SER A 1 466 ? 146.500 143.243 103.409 1.00 44.87  ? 466  SER A CB  1 
ATOM   2479  O OG  . SER A 1 466 ? 146.191 143.817 102.152 1.00 44.87  ? 466  SER A OG  1 
ATOM   2480  N N   . LYS A 1 467 ? 147.431 143.132 106.181 1.00 50.05  ? 467  LYS A N   1 
ATOM   2481  C CA  . LYS A 1 467 ? 148.033 143.022 107.521 1.00 50.05  ? 467  LYS A CA  1 
ATOM   2482  C C   . LYS A 1 467 ? 147.201 142.198 108.511 1.00 50.05  ? 467  LYS A C   1 
ATOM   2483  O O   . LYS A 1 467 ? 146.993 142.592 109.660 1.00 50.05  ? 467  LYS A O   1 
ATOM   2484  C CB  . LYS A 1 467 ? 148.296 144.424 108.074 1.00 50.05  ? 467  LYS A CB  1 
ATOM   2485  C CG  . LYS A 1 467 ? 149.470 144.559 109.042 1.00 50.05  ? 467  LYS A CG  1 
ATOM   2486  C CD  . LYS A 1 467 ? 149.446 145.929 109.706 1.00 50.05  ? 467  LYS A CD  1 
ATOM   2487  C CE  . LYS A 1 467 ? 150.553 146.076 110.727 1.00 50.05  ? 467  LYS A CE  1 
ATOM   2488  N NZ  . LYS A 1 467 ? 150.348 145.161 111.875 1.00 50.05  ? 467  LYS A NZ  1 
ATOM   2489  N N   . ASN A 1 468 ? 146.702 141.052 108.024 1.00 51.01  ? 468  ASN A N   1 
ATOM   2490  C CA  . ASN A 1 468 ? 145.874 140.107 108.790 1.00 51.01  ? 468  ASN A CA  1 
ATOM   2491  C C   . ASN A 1 468 ? 144.609 140.787 109.325 1.00 51.01  ? 468  ASN A C   1 
ATOM   2492  O O   . ASN A 1 468 ? 144.504 141.097 110.515 1.00 51.01  ? 468  ASN A O   1 
ATOM   2493  C CB  . ASN A 1 468 ? 146.661 139.443 109.931 1.00 51.01  ? 468  ASN A CB  1 
ATOM   2494  C CG  . ASN A 1 468 ? 147.766 138.538 109.434 1.00 51.01  ? 468  ASN A CG  1 
ATOM   2495  O OD1 . ASN A 1 468 ? 147.627 137.316 109.435 1.00 51.01  ? 468  ASN A OD1 1 
ATOM   2496  N ND2 . ASN A 1 468 ? 148.879 139.132 109.021 1.00 51.01  ? 468  ASN A ND2 1 
ATOM   2497  N N   . GLU A 1 469 ? 143.703 141.091 108.383 1.00 42.08  ? 469  GLU A N   1 
ATOM   2498  C CA  . GLU A 1 469 ? 142.457 141.808 108.667 1.00 42.08  ? 469  GLU A CA  1 
ATOM   2499  C C   . GLU A 1 469 ? 141.654 141.165 109.793 1.00 42.08  ? 469  GLU A C   1 
ATOM   2500  O O   . GLU A 1 469 ? 141.157 140.044 109.655 1.00 42.08  ? 469  GLU A O   1 
ATOM   2501  C CB  . GLU A 1 469 ? 141.566 141.866 107.419 1.00 42.08  ? 469  GLU A CB  1 
ATOM   2502  C CG  . GLU A 1 469 ? 142.017 142.757 106.269 1.00 42.08  ? 469  GLU A CG  1 
ATOM   2503  C CD  . GLU A 1 469 ? 142.591 141.970 105.109 1.00 42.08  ? 469  GLU A CD  1 
ATOM   2504  O OE1 . GLU A 1 469 ? 142.678 140.731 105.222 1.00 42.08  ? 469  GLU A OE1 1 
ATOM   2505  O OE2 . GLU A 1 469 ? 142.926 142.585 104.074 1.00 42.08  ? 469  GLU A OE2 1 
ATOM   2506  N N   . LEU A 1 470 ? 141.542 141.880 110.913 1.00 29.27  ? 470  LEU A N   1 
ATOM   2507  C CA  . LEU A 1 470 ? 140.619 141.494 111.971 1.00 29.27  ? 470  LEU A CA  1 
ATOM   2508  C C   . LEU A 1 470 ? 139.190 141.660 111.496 1.00 29.27  ? 470  LEU A C   1 
ATOM   2509  O O   . LEU A 1 470 ? 138.882 142.559 110.712 1.00 29.27  ? 470  LEU A O   1 
ATOM   2510  C CB  . LEU A 1 470 ? 140.843 142.322 113.234 1.00 29.27  ? 470  LEU A CB  1 
ATOM   2511  C CG  . LEU A 1 470 ? 141.736 141.717 114.312 1.00 29.27  ? 470  LEU A CG  1 
ATOM   2512  C CD1 . LEU A 1 470 ? 143.129 141.560 113.815 1.00 29.27  ? 470  LEU A CD1 1 
ATOM   2513  C CD2 . LEU A 1 470 ? 141.740 142.578 115.551 1.00 29.27  ? 470  LEU A CD2 1 
ATOM   2514  N N   . LYS A 1 471 ? 138.324 140.779 111.952 1.00 21.38  ? 471  LYS A N   1 
ATOM   2515  C CA  . LYS A 1 471 ? 136.929 140.828 111.570 1.00 21.38  ? 471  LYS A CA  1 
ATOM   2516  C C   . LYS A 1 471 ? 136.090 141.049 112.817 1.00 21.38  ? 471  LYS A C   1 
ATOM   2517  O O   . LYS A 1 471 ? 136.608 141.265 113.906 1.00 21.38  ? 471  LYS A O   1 
ATOM   2518  C CB  . LYS A 1 471 ? 136.532 139.550 110.838 1.00 21.38  ? 471  LYS A CB  1 
ATOM   2519  C CG  . LYS A 1 471 ? 137.235 139.344 109.517 1.00 21.38  ? 471  LYS A CG  1 
ATOM   2520  C CD  . LYS A 1 471 ? 136.801 138.038 108.886 1.00 21.38  ? 471  LYS A CD  1 
ATOM   2521  C CE  . LYS A 1 471 ? 135.385 138.134 108.345 1.00 21.38  ? 471  LYS A CE  1 
ATOM   2522  N NZ  . LYS A 1 471 ? 135.333 139.017 107.153 1.00 21.38  ? 471  LYS A NZ  1 
ATOM   2523  N N   . TYR A 1 472 ? 134.777 140.980 112.652 1.00 17.11  ? 472  TYR A N   1 
ATOM   2524  C CA  . TYR A 1 472 ? 133.865 141.043 113.781 1.00 17.11  ? 472  TYR A CA  1 
ATOM   2525  C C   . TYR A 1 472 ? 133.599 139.676 114.394 1.00 17.11  ? 472  TYR A C   1 
ATOM   2526  O O   . TYR A 1 472 ? 132.704 139.539 115.236 1.00 17.11  ? 472  TYR A O   1 
ATOM   2527  C CB  . TYR A 1 472 ? 132.557 141.711 113.369 1.00 17.11  ? 472  TYR A CB  1 
ATOM   2528  C CG  . TYR A 1 472 ? 131.698 140.909 112.433 1.00 17.11  ? 472  TYR A CG  1 
ATOM   2529  C CD1 . TYR A 1 472 ? 131.979 140.862 111.075 1.00 17.11  ? 472  TYR A CD1 1 
ATOM   2530  C CD2 . TYR A 1 472 ? 130.586 140.227 112.900 1.00 17.11  ? 472  TYR A CD2 1 
ATOM   2531  C CE1 . TYR A 1 472 ? 131.198 140.147 110.218 1.00 17.11  ? 472  TYR A CE1 1 
ATOM   2532  C CE2 . TYR A 1 472 ? 129.796 139.507 112.050 1.00 17.11  ? 472  TYR A CE2 1 
ATOM   2533  C CZ  . TYR A 1 472 ? 130.105 139.470 110.708 1.00 17.11  ? 472  TYR A CZ  1 
ATOM   2534  O OH  . TYR A 1 472 ? 129.318 138.747 109.842 1.00 17.11  ? 472  TYR A OH  1 
ATOM   2535  N N   . ARG A 1 473 ? 134.337 138.656 113.976 1.00 20.81  ? 473  ARG A N   1 
ATOM   2536  C CA  . ARG A 1 473 ? 134.380 137.390 114.678 1.00 20.81  ? 473  ARG A CA  1 
ATOM   2537  C C   . ARG A 1 473 ? 135.701 137.172 115.379 1.00 20.81  ? 473  ARG A C   1 
ATOM   2538  O O   . ARG A 1 473 ? 135.825 136.210 116.136 1.00 20.81  ? 473  ARG A O   1 
ATOM   2539  C CB  . ARG A 1 473 ? 134.136 136.219 113.716 1.00 20.81  ? 473  ARG A CB  1 
ATOM   2540  C CG  . ARG A 1 473 ? 132.908 136.356 112.846 1.00 20.81  ? 473  ARG A CG  1 
ATOM   2541  C CD  . ARG A 1 473 ? 132.243 135.018 112.592 1.00 20.81  ? 473  ARG A CD  1 
ATOM   2542  N NE  . ARG A 1 473 ? 130.882 135.184 112.096 1.00 20.81  ? 473  ARG A NE  1 
ATOM   2543  C CZ  . ARG A 1 473 ? 129.824 135.392 112.873 1.00 20.81  ? 473  ARG A CZ  1 
ATOM   2544  N NH1 . ARG A 1 473 ? 129.959 135.458 114.191 1.00 20.81  ? 473  ARG A NH1 1 
ATOM   2545  N NH2 . ARG A 1 473 ? 128.625 135.534 112.330 1.00 20.81  ? 473  ARG A NH2 1 
ATOM   2546  N N   . ASP A 1 474 ? 136.695 138.013 115.132 1.00 22.67  ? 474  ASP A N   1 
ATOM   2547  C CA  . ASP A 1 474 ? 137.962 137.926 115.827 1.00 22.67  ? 474  ASP A CA  1 
ATOM   2548  C C   . ASP A 1 474 ? 138.146 139.016 116.872 1.00 22.67  ? 474  ASP A C   1 
ATOM   2549  O O   . ASP A 1 474 ? 139.253 139.159 117.391 1.00 22.67  ? 474  ASP A O   1 
ATOM   2550  C CB  . ASP A 1 474 ? 139.131 137.982 114.838 1.00 22.67  ? 474  ASP A CB  1 
ATOM   2551  C CG  . ASP A 1 474 ? 139.066 136.890 113.783 1.00 22.67  ? 474  ASP A CG  1 
ATOM   2552  O OD1 . ASP A 1 474 ? 138.070 136.143 113.748 1.00 22.67  ? 474  ASP A OD1 1 
ATOM   2553  O OD2 . ASP A 1 474 ? 140.024 136.768 112.989 1.00 22.67  ? 474  ASP A OD2 1 
ATOM   2554  N N   . VAL A 1 475 ? 137.114 139.810 117.165 1.00 13.95  ? 475  VAL A N   1 
ATOM   2555  C CA  . VAL A 1 475 ? 137.099 140.690 118.330 1.00 13.95  ? 475  VAL A CA  1 
ATOM   2556  C C   . VAL A 1 475 ? 135.859 140.376 119.141 1.00 13.95  ? 475  VAL A C   1 
ATOM   2557  O O   . VAL A 1 475 ? 135.735 140.802 120.289 1.00 13.95  ? 475  VAL A O   1 
ATOM   2558  C CB  . VAL A 1 475 ? 137.132 142.175 117.955 1.00 13.95  ? 475  VAL A CB  1 
ATOM   2559  C CG1 . VAL A 1 475 ? 138.464 142.546 117.389 1.00 13.95  ? 475  VAL A CG1 1 
ATOM   2560  C CG2 . VAL A 1 475 ? 136.120 142.419 116.948 1.00 13.95  ? 475  VAL A CG2 1 
ATOM   2561  N N   . PHE A 1 476 ? 134.928 139.640 118.554 1.00 18.00  ? 476  PHE A N   1 
ATOM   2562  C CA  . PHE A 1 476 ? 133.898 138.990 119.346 1.00 18.00  ? 476  PHE A CA  1 
ATOM   2563  C C   . PHE A 1 476 ? 134.422 137.745 120.027 1.00 18.00  ? 476  PHE A C   1 
ATOM   2564  O O   . PHE A 1 476 ? 133.766 137.220 120.929 1.00 18.00  ? 476  PHE A O   1 
ATOM   2565  C CB  . PHE A 1 476 ? 132.710 138.591 118.483 1.00 18.00  ? 476  PHE A CB  1 
ATOM   2566  C CG  . PHE A 1 476 ? 131.709 139.672 118.271 1.00 18.00  ? 476  PHE A CG  1 
ATOM   2567  C CD1 . PHE A 1 476 ? 131.998 140.977 118.555 1.00 18.00  ? 476  PHE A CD1 1 
ATOM   2568  C CD2 . PHE A 1 476 ? 130.467 139.366 117.769 1.00 18.00  ? 476  PHE A CD2 1 
ATOM   2569  C CE1 . PHE A 1 476 ? 131.073 141.947 118.340 1.00 18.00  ? 476  PHE A CE1 1 
ATOM   2570  C CE2 . PHE A 1 476 ? 129.538 140.342 117.556 1.00 18.00  ? 476  PHE A CE2 1 
ATOM   2571  C CZ  . PHE A 1 476 ? 129.841 141.631 117.843 1.00 18.00  ? 476  PHE A CZ  1 
ATOM   2572  N N   . LEU A 1 477 ? 135.576 137.257 119.597 1.00 14.75  ? 477  LEU A N   1 
ATOM   2573  C CA  . LEU A 1 477 ? 136.232 136.108 120.190 1.00 14.75  ? 477  LEU A CA  1 
ATOM   2574  C C   . LEU A 1 477 ? 137.204 136.501 121.286 1.00 14.75  ? 477  LEU A C   1 
ATOM   2575  O O   . LEU A 1 477 ? 137.338 135.765 122.257 1.00 14.75  ? 477  LEU A O   1 
ATOM   2576  C CB  . LEU A 1 477 ? 136.965 135.314 119.110 1.00 14.75  ? 477  LEU A CB  1 
ATOM   2577  C CG  . LEU A 1 477 ? 137.484 133.934 119.471 1.00 14.75  ? 477  LEU A CG  1 
ATOM   2578  C CD1 . LEU A 1 477 ? 136.335 132.996 119.635 1.00 14.75  ? 477  LEU A CD1 1 
ATOM   2579  C CD2 . LEU A 1 477 ? 138.406 133.452 118.391 1.00 14.75  ? 477  LEU A CD2 1 
ATOM   2580  N N   . ILE A 1 478 ? 137.880 137.645 121.162 1.00 10.46  ? 478  ILE A N   1 
ATOM   2581  C CA  . ILE A 1 478 ? 138.739 138.114 122.244 1.00 10.46  ? 478  ILE A CA  1 
ATOM   2582  C C   . ILE A 1 478 ? 137.910 138.551 123.435 1.00 10.46  ? 478  ILE A C   1 
ATOM   2583  O O   . ILE A 1 478 ? 138.231 138.230 124.579 1.00 10.46  ? 478  ILE A O   1 
ATOM   2584  C CB  . ILE A 1 478 ? 139.637 139.266 121.779 1.00 10.46  ? 478  ILE A CB  1 
ATOM   2585  C CG1 . ILE A 1 478 ? 140.282 138.959 120.449 1.00 10.46  ? 478  ILE A CG1 1 
ATOM   2586  C CG2 . ILE A 1 478 ? 140.694 139.546 122.811 1.00 10.46  ? 478  ILE A CG2 1 
ATOM   2587  C CD1 . ILE A 1 478 ? 141.082 140.113 119.931 1.00 10.46  ? 478  ILE A CD1 1 
ATOM   2588  N N   . CYS A 1 479 ? 136.830 139.288 123.191 1.00 10.00  ? 479  CYS A N   1 
ATOM   2589  C CA  . CYS A 1 479 ? 136.091 139.915 124.273 1.00 10.00  ? 479  CYS A CA  1 
ATOM   2590  C C   . CYS A 1 479 ? 135.212 138.943 125.034 1.00 10.00  ? 479  CYS A C   1 
ATOM   2591  O O   . CYS A 1 479 ? 134.678 139.315 126.081 1.00 10.00  ? 479  CYS A O   1 
ATOM   2592  C CB  . CYS A 1 479 ? 135.234 141.051 123.735 1.00 10.00  ? 479  CYS A CB  1 
ATOM   2593  S SG  . CYS A 1 479 ? 133.753 140.516 122.923 1.00 10.00  ? 479  CYS A SG  1 
ATOM   2594  N N   . THR A 1 480 ? 135.050 137.719 124.539 1.00 7.00   ? 480  THR A N   1 
ATOM   2595  C CA  . THR A 1 480 ? 134.307 136.662 125.210 1.00 7.00   ? 480  THR A CA  1 
ATOM   2596  C C   . THR A 1 480 ? 135.192 135.591 125.818 1.00 7.00   ? 480  THR A C   1 
ATOM   2597  O O   . THR A 1 480 ? 134.924 135.148 126.931 1.00 7.00   ? 480  THR A O   1 
ATOM   2598  C CB  . THR A 1 480 ? 133.339 136.010 124.233 1.00 7.00   ? 480  THR A CB  1 
ATOM   2599  O OG1 . THR A 1 480 ? 134.050 135.656 123.047 1.00 7.00   ? 480  THR A OG1 1 
ATOM   2600  C CG2 . THR A 1 480 ? 132.230 136.949 123.885 1.00 7.00   ? 480  THR A CG2 1 
ATOM   2601  N N   . ALA A 1 481 ? 136.245 135.162 125.117 1.00 5.28   ? 481  ALA A N   1 
ATOM   2602  C CA  . ALA A 1 481 ? 137.180 134.191 125.671 1.00 5.28   ? 481  ALA A CA  1 
ATOM   2603  C C   . ALA A 1 481 ? 137.962 134.742 126.843 1.00 5.28   ? 481  ALA A C   1 
ATOM   2604  O O   . ALA A 1 481 ? 138.401 133.969 127.695 1.00 5.28   ? 481  ALA A O   1 
ATOM   2605  C CB  . ALA A 1 481 ? 138.164 133.719 124.609 1.00 5.28   ? 481  ALA A CB  1 
ATOM   2606  N N   . SER A 1 482 ? 138.149 136.054 126.907 1.00 9.20   ? 482  SER A N   1 
ATOM   2607  C CA  . SER A 1 482 ? 138.908 136.661 127.983 1.00 9.20   ? 482  SER A CA  1 
ATOM   2608  C C   . SER A 1 482 ? 138.044 137.327 129.028 1.00 9.20   ? 482  SER A C   1 
ATOM   2609  O O   . SER A 1 482 ? 138.588 137.930 129.948 1.00 9.20   ? 482  SER A O   1 
ATOM   2610  C CB  . SER A 1 482 ? 139.877 137.691 127.425 1.00 9.20   ? 482  SER A CB  1 
ATOM   2611  O OG  . SER A 1 482 ? 139.220 138.548 126.528 1.00 9.20   ? 482  SER A OG  1 
ATOM   2612  N N   . MET A 1 483 ? 136.727 137.263 128.894 1.00 13.53  ? 483  MET A N   1 
ATOM   2613  C CA  . MET A 1 483 ? 135.834 137.713 129.947 1.00 13.53  ? 483  MET A CA  1 
ATOM   2614  C C   . MET A 1 483 ? 135.245 136.548 130.726 1.00 13.53  ? 483  MET A C   1 
ATOM   2615  O O   . MET A 1 483 ? 134.819 136.730 131.871 1.00 13.53  ? 483  MET A O   1 
ATOM   2616  C CB  . MET A 1 483 ? 134.730 138.592 129.351 1.00 13.53  ? 483  MET A CB  1 
ATOM   2617  C CG  . MET A 1 483 ? 133.984 139.455 130.352 1.00 13.53  ? 483  MET A CG  1 
ATOM   2618  S SD  . MET A 1 483 ? 135.077 140.316 131.488 1.00 13.53  ? 483  MET A SD  1 
ATOM   2619  C CE  . MET A 1 483 ? 134.056 140.432 132.950 1.00 13.53  ? 483  MET A CE  1 
ATOM   2620  N N   . SER A 1 484 ? 135.237 135.351 130.145 1.00 10.62  ? 484  SER A N   1 
ATOM   2621  C CA  . SER A 1 484 ? 135.010 134.148 130.928 1.00 10.62  ? 484  SER A CA  1 
ATOM   2622  C C   . SER A 1 484 ? 136.261 133.709 131.667 1.00 10.62  ? 484  SER A C   1 
ATOM   2623  O O   . SER A 1 484 ? 136.160 132.933 132.620 1.00 10.62  ? 484  SER A O   1 
ATOM   2624  C CB  . SER A 1 484 ? 134.548 133.013 130.036 1.00 10.62  ? 484  SER A CB  1 
ATOM   2625  O OG  . SER A 1 484 ? 135.669 132.385 129.467 1.00 10.62  ? 484  SER A OG  1 
ATOM   2626  N N   . ALA A 1 485 ? 137.436 134.178 131.236 1.00 12.08  ? 485  ALA A N   1 
ATOM   2627  C CA  . ALA A 1 485 ? 138.672 133.911 131.960 1.00 12.08  ? 485  ALA A CA  1 
ATOM   2628  C C   . ALA A 1 485 ? 138.825 134.817 133.172 1.00 12.08  ? 485  ALA A C   1 
ATOM   2629  O O   . ALA A 1 485 ? 139.649 134.539 134.042 1.00 12.08  ? 485  ALA A O   1 
ATOM   2630  C CB  . ALA A 1 485 ? 139.873 134.062 131.030 1.00 12.08  ? 485  ALA A CB  1 
ATOM   2631  N N   . ILE A 1 486 ? 138.069 135.911 133.241 1.00 14.68  ? 486  ILE A N   1 
ATOM   2632  C CA  . ILE A 1 486 ? 138.030 136.717 134.455 1.00 14.68  ? 486  ILE A CA  1 
ATOM   2633  C C   . ILE A 1 486 ? 136.880 136.281 135.338 1.00 14.68  ? 486  ILE A C   1 
ATOM   2634  O O   . ILE A 1 486 ? 137.033 136.139 136.554 1.00 14.68  ? 486  ILE A O   1 
ATOM   2635  C CB  . ILE A 1 486 ? 137.929 138.209 134.110 1.00 14.68  ? 486  ILE A CB  1 
ATOM   2636  C CG1 . ILE A 1 486 ? 139.192 138.658 133.412 1.00 14.68  ? 486  ILE A CG1 1 
ATOM   2637  C CG2 . ILE A 1 486 ? 137.738 139.042 135.343 1.00 14.68  ? 486  ILE A CG2 1 
ATOM   2638  C CD1 . ILE A 1 486 ? 138.975 139.831 132.535 1.00 14.68  ? 486  ILE A CD1 1 
ATOM   2639  N N   . ALA A 1 487 ? 135.720 136.012 134.735 1.00 14.92  ? 487  ALA A N   1 
ATOM   2640  C CA  . ALA A 1 487 ? 134.569 135.548 135.498 1.00 14.92  ? 487  ALA A CA  1 
ATOM   2641  C C   . ALA A 1 487 ? 134.765 134.147 136.058 1.00 14.92  ? 487  ALA A C   1 
ATOM   2642  O O   . ALA A 1 487 ? 133.993 133.731 136.923 1.00 14.92  ? 487  ALA A O   1 
ATOM   2643  C CB  . ALA A 1 487 ? 133.313 135.586 134.640 1.00 14.92  ? 487  ALA A CB  1 
ATOM   2644  N N   . GLY A 1 488 ? 135.774 133.415 135.589 1.00 16.21  ? 488  GLY A N   1 
ATOM   2645  C CA  . GLY A 1 488 ? 136.213 132.198 136.236 1.00 16.21  ? 488  GLY A CA  1 
ATOM   2646  C C   . GLY A 1 488 ? 137.137 132.461 137.405 1.00 16.21  ? 488  GLY A C   1 
ATOM   2647  O O   . GLY A 1 488 ? 136.878 131.989 138.512 1.00 16.21  ? 488  GLY A O   1 
ATOM   2648  N N   . VAL A 1 489 ? 138.213 133.221 137.174 1.00 14.33  ? 489  VAL A N   1 
ATOM   2649  C CA  . VAL A 1 489 ? 139.202 133.486 138.218 1.00 14.33  ? 489  VAL A CA  1 
ATOM   2650  C C   . VAL A 1 489 ? 138.618 134.382 139.310 1.00 14.33  ? 489  VAL A C   1 
ATOM   2651  O O   . VAL A 1 489 ? 138.997 134.276 140.481 1.00 14.33  ? 489  VAL A O   1 
ATOM   2652  C CB  . VAL A 1 489 ? 140.474 134.056 137.561 1.00 14.33  ? 489  VAL A CB  1 
ATOM   2653  C CG1 . VAL A 1 489 ? 141.539 134.399 138.564 1.00 14.33  ? 489  VAL A CG1 1 
ATOM   2654  C CG2 . VAL A 1 489 ? 141.031 133.042 136.604 1.00 14.33  ? 489  VAL A CG2 1 
ATOM   2655  N N   . MET A 1 490 ? 137.629 135.212 138.977 1.00 16.45  ? 490  MET A N   1 
ATOM   2656  C CA  . MET A 1 490 ? 136.815 135.867 139.993 1.00 16.45  ? 490  MET A CA  1 
ATOM   2657  C C   . MET A 1 490 ? 135.567 135.072 140.332 1.00 16.45  ? 490  MET A C   1 
ATOM   2658  O O   . MET A 1 490 ? 134.537 135.659 140.677 1.00 16.45  ? 490  MET A O   1 
ATOM   2659  C CB  . MET A 1 490 ? 136.433 137.285 139.571 1.00 16.45  ? 490  MET A CB  1 
ATOM   2660  C CG  . MET A 1 490 ? 137.589 138.202 139.209 1.00 16.45  ? 490  MET A CG  1 
ATOM   2661  S SD  . MET A 1 490 ? 139.115 137.900 140.110 1.00 16.45  ? 490  MET A SD  1 
ATOM   2662  C CE  . MET A 1 490 ? 138.679 138.493 141.734 1.00 16.45  ? 490  MET A CE  1 
ATOM   2663  N N   . PHE A 1 491 ? 135.621 133.751 140.193 1.00 21.61  ? 491  PHE A N   1 
ATOM   2664  C CA  . PHE A 1 491 ? 134.691 132.851 140.858 1.00 21.61  ? 491  PHE A CA  1 
ATOM   2665  C C   . PHE A 1 491 ? 135.395 131.866 141.777 1.00 21.61  ? 491  PHE A C   1 
ATOM   2666  O O   . PHE A 1 491 ? 134.859 131.538 142.835 1.00 21.61  ? 491  PHE A O   1 
ATOM   2667  C CB  . PHE A 1 491 ? 133.856 132.085 139.827 1.00 21.61  ? 491  PHE A CB  1 
ATOM   2668  C CG  . PHE A 1 491 ? 133.010 131.004 140.416 1.00 21.61  ? 491  PHE A CG  1 
ATOM   2669  C CD1 . PHE A 1 491 ? 132.051 131.298 141.368 1.00 21.61  ? 491  PHE A CD1 1 
ATOM   2670  C CD2 . PHE A 1 491 ? 133.173 129.696 140.017 1.00 21.61  ? 491  PHE A CD2 1 
ATOM   2671  C CE1 . PHE A 1 491 ? 131.285 130.303 141.918 1.00 21.61  ? 491  PHE A CE1 1 
ATOM   2672  C CE2 . PHE A 1 491 ? 132.403 128.704 140.553 1.00 21.61  ? 491  PHE A CE2 1 
ATOM   2673  C CZ  . PHE A 1 491 ? 131.454 129.009 141.506 1.00 21.61  ? 491  PHE A CZ  1 
ATOM   2674  N N   . VAL A 1 492 ? 136.612 131.434 141.425 1.00 20.54  ? 492  VAL A N   1 
ATOM   2675  C CA  . VAL A 1 492 ? 137.450 130.673 142.345 1.00 20.54  ? 492  VAL A CA  1 
ATOM   2676  C C   . VAL A 1 492 ? 138.016 131.536 143.463 1.00 20.54  ? 492  VAL A C   1 
ATOM   2677  O O   . VAL A 1 492 ? 138.579 130.998 144.424 1.00 20.54  ? 492  VAL A O   1 
ATOM   2678  C CB  . VAL A 1 492 ? 138.611 129.979 141.601 1.00 20.54  ? 492  VAL A CB  1 
ATOM   2679  C CG1 . VAL A 1 492 ? 138.111 129.338 140.327 1.00 20.54  ? 492  VAL A CG1 1 
ATOM   2680  C CG2 . VAL A 1 492 ? 139.739 130.947 141.308 1.00 20.54  ? 492  VAL A CG2 1 
ATOM   2681  N N   . HIS A 1 493 ? 137.887 132.857 143.368 1.00 26.72  ? 493  HIS A N   1 
ATOM   2682  C CA  . HIS A 1 493 ? 138.353 133.794 144.375 1.00 26.72  ? 493  HIS A CA  1 
ATOM   2683  C C   . HIS A 1 493 ? 137.238 134.241 145.311 1.00 26.72  ? 493  HIS A C   1 
ATOM   2684  O O   . HIS A 1 493 ? 137.527 134.759 146.392 1.00 26.72  ? 493  HIS A O   1 
ATOM   2685  C CB  . HIS A 1 493 ? 138.991 135.002 143.676 1.00 26.72  ? 493  HIS A CB  1 
ATOM   2686  C CG  . HIS A 1 493 ? 139.638 135.987 144.595 1.00 26.72  ? 493  HIS A CG  1 
ATOM   2687  N ND1 . HIS A 1 493 ? 138.918 136.918 145.312 1.00 26.72  ? 493  HIS A ND1 1 
ATOM   2688  C CD2 . HIS A 1 493 ? 140.939 136.211 144.886 1.00 26.72  ? 493  HIS A CD2 1 
ATOM   2689  C CE1 . HIS A 1 493 ? 139.749 137.663 146.017 1.00 26.72  ? 493  HIS A CE1 1 
ATOM   2690  N NE2 . HIS A 1 493 ? 140.981 137.256 145.775 1.00 26.72  ? 493  HIS A NE2 1 
ATOM   2691  N N   . LEU A 1 494 ? 135.979 134.056 144.933 1.00 27.94  ? 494  LEU A N   1 
ATOM   2692  C CA  . LEU A 1 494 ? 134.885 134.222 145.874 1.00 27.94  ? 494  LEU A CA  1 
ATOM   2693  C C   . LEU A 1 494 ? 134.774 133.038 146.825 1.00 27.94  ? 494  LEU A C   1 
ATOM   2694  O O   . LEU A 1 494 ? 134.527 133.236 148.021 1.00 27.94  ? 494  LEU A O   1 
ATOM   2695  C CB  . LEU A 1 494 ? 133.563 134.417 145.135 1.00 27.94  ? 494  LEU A CB  1 
ATOM   2696  C CG  . LEU A 1 494 ? 132.372 134.756 146.037 1.00 27.94  ? 494  LEU A CG  1 
ATOM   2697  C CD1 . LEU A 1 494 ? 132.503 136.149 146.615 1.00 27.94  ? 494  LEU A CD1 1 
ATOM   2698  C CD2 . LEU A 1 494 ? 131.063 134.595 145.322 1.00 27.94  ? 494  LEU A CD2 1 
ATOM   2699  N N   . SER A 1 495 ? 134.974 131.819 146.321 1.00 33.79  ? 495  SER A N   1 
ATOM   2700  C CA  . SER A 1 495 ? 134.915 130.588 147.100 1.00 33.79  ? 495  SER A CA  1 
ATOM   2701  C C   . SER A 1 495 ? 135.942 130.561 148.215 1.00 33.79  ? 495  SER A C   1 
ATOM   2702  O O   . SER A 1 495 ? 135.606 130.233 149.354 1.00 33.79  ? 495  SER A O   1 
ATOM   2703  C CB  . SER A 1 495 ? 135.144 129.373 146.199 1.00 33.79  ? 495  SER A CB  1 
ATOM   2704  O OG  . SER A 1 495 ? 136.532 129.186 145.987 1.00 33.79  ? 495  SER A OG  1 
ATOM   2705  N N   . LEU A 1 496 ? 137.188 130.919 147.902 1.00 35.65  ? 496  LEU A N   1 
ATOM   2706  C CA  . LEU A 1 496 ? 138.233 131.002 148.911 1.00 35.65  ? 496  LEU A CA  1 
ATOM   2707  C C   . LEU A 1 496 ? 137.924 132.056 149.966 1.00 35.65  ? 496  LEU A C   1 
ATOM   2708  O O   . LEU A 1 496 ? 138.347 131.902 151.115 1.00 35.65  ? 496  LEU A O   1 
ATOM   2709  C CB  . LEU A 1 496 ? 139.581 131.291 148.243 1.00 35.65  ? 496  LEU A CB  1 
ATOM   2710  C CG  . LEU A 1 496 ? 140.077 130.224 147.264 1.00 35.65  ? 496  LEU A CG  1 
ATOM   2711  C CD1 . LEU A 1 496 ? 141.340 130.652 146.577 1.00 35.65  ? 496  LEU A CD1 1 
ATOM   2712  C CD2 . LEU A 1 496 ? 140.313 128.925 147.964 1.00 35.65  ? 496  LEU A CD2 1 
ATOM   2713  N N   . LEU A 1 497 ? 137.164 133.095 149.616 1.00 40.03  ? 497  LEU A N   1 
ATOM   2714  C CA  . LEU A 1 497 ? 136.736 134.105 150.573 1.00 40.03  ? 497  LEU A CA  1 
ATOM   2715  C C   . LEU A 1 497 ? 135.302 133.872 151.031 1.00 40.03  ? 497  LEU A C   1 
ATOM   2716  O O   . LEU A 1 497 ? 134.628 134.796 151.489 1.00 40.03  ? 497  LEU A O   1 
ATOM   2717  C CB  . LEU A 1 497 ? 136.897 135.507 149.994 1.00 40.03  ? 497  LEU A CB  1 
ATOM   2718  C CG  . LEU A 1 497 ? 138.342 135.914 149.728 1.00 40.03  ? 497  LEU A CG  1 
ATOM   2719  C CD1 . LEU A 1 497 ? 138.385 137.342 149.252 1.00 40.03  ? 497  LEU A CD1 1 
ATOM   2720  C CD2 . LEU A 1 497 ? 139.193 135.735 150.966 1.00 40.03  ? 497  LEU A CD2 1 
ATOM   2721  N N   . GLU A 1 498 ? 134.820 132.639 150.908 1.00 52.18  ? 498  GLU A N   1 
ATOM   2722  C CA  . GLU A 1 498 ? 133.630 132.238 151.645 1.00 52.18  ? 498  GLU A CA  1 
ATOM   2723  C C   . GLU A 1 498 ? 134.003 131.529 152.941 1.00 52.18  ? 498  GLU A C   1 
ATOM   2724  O O   . GLU A 1 498 ? 133.322 131.691 153.959 1.00 52.18  ? 498  GLU A O   1 
ATOM   2725  C CB  . GLU A 1 498 ? 132.748 131.334 150.780 1.00 52.18  ? 498  GLU A CB  1 
ATOM   2726  C CG  . GLU A 1 498 ? 131.362 131.055 151.346 1.00 52.18  ? 498  GLU A CG  1 
ATOM   2727  C CD  . GLU A 1 498 ? 130.400 130.554 150.288 1.00 52.18  ? 498  GLU A CD  1 
ATOM   2728  O OE1 . GLU A 1 498 ? 130.678 129.499 149.682 1.00 52.18  ? 498  GLU A OE1 1 
ATOM   2729  O OE2 . GLU A 1 498 ? 129.369 131.214 150.052 1.00 52.18  ? 498  GLU A OE2 1 
ATOM   2730  N N   . LYS A 1 499 ? 135.091 130.762 152.917 1.00 43.52  ? 499  LYS A N   1 
ATOM   2731  C CA  . LYS A 1 499 ? 135.589 130.038 154.078 1.00 43.52  ? 499  LYS A CA  1 
ATOM   2732  C C   . LYS A 1 499 ? 136.860 130.641 154.661 1.00 43.52  ? 499  LYS A C   1 
ATOM   2733  O O   . LYS A 1 499 ? 137.160 130.415 155.836 1.00 43.52  ? 499  LYS A O   1 
ATOM   2734  C CB  . LYS A 1 499 ? 135.840 128.573 153.708 1.00 43.52  ? 499  LYS A CB  1 
ATOM   2735  C CG  . LYS A 1 499 ? 136.972 128.354 152.715 1.00 43.52  ? 499  LYS A CG  1 
ATOM   2736  C CD  . LYS A 1 499 ? 137.117 126.891 152.350 1.00 43.52  ? 499  LYS A CD  1 
ATOM   2737  C CE  . LYS A 1 499 ? 138.525 126.577 151.877 1.00 43.52  ? 499  LYS A CE  1 
ATOM   2738  N NZ  . LYS A 1 499 ? 138.888 127.350 150.673 1.00 43.52  ? 499  LYS A NZ  1 
ATOM   2739  N N   . GLY A 1 500 ? 137.616 131.406 153.875 1.00 47.01  ? 500  GLY A N   1 
ATOM   2740  C CA  . GLY A 1 500 ? 138.876 131.953 154.339 1.00 47.01  ? 500  GLY A CA  1 
ATOM   2741  C C   . GLY A 1 500 ? 140.037 131.028 154.038 1.00 47.01  ? 500  GLY A C   1 
ATOM   2742  O O   . GLY A 1 500 ? 140.068 129.889 154.511 1.00 47.01  ? 500  GLY A O   1 
ATOM   2743  N N   . TYR A 1 501 ? 140.983 131.489 153.230 1.00 47.71  ? 501  TYR A N   1 
ATOM   2744  C CA  . TYR A 1 501 ? 142.154 130.699 152.859 1.00 47.71  ? 501  TYR A CA  1 
ATOM   2745  C C   . TYR A 1 501 ? 143.410 131.573 152.895 1.00 47.71  ? 501  TYR A C   1 
ATOM   2746  O O   . TYR A 1 501 ? 144.062 131.796 151.872 1.00 47.71  ? 501  TYR A O   1 
ATOM   2747  C CB  . TYR A 1 501 ? 141.970 130.004 151.508 1.00 47.71  ? 501  TYR A CB  1 
ATOM   2748  C CG  . TYR A 1 501 ? 143.080 129.020 151.174 1.00 47.71  ? 501  TYR A CG  1 
ATOM   2749  C CD1 . TYR A 1 501 ? 143.627 128.200 152.154 1.00 47.71  ? 501  TYR A CD1 1 
ATOM   2750  C CD2 . TYR A 1 501 ? 143.593 128.930 149.885 1.00 47.71  ? 501  TYR A CD2 1 
ATOM   2751  C CE1 . TYR A 1 501 ? 144.648 127.311 151.857 1.00 47.71  ? 501  TYR A CE1 1 
ATOM   2752  C CE2 . TYR A 1 501 ? 144.612 128.042 149.579 1.00 47.71  ? 501  TYR A CE2 1 
ATOM   2753  C CZ  . TYR A 1 501 ? 145.133 127.237 150.568 1.00 47.71  ? 501  TYR A CZ  1 
ATOM   2754  O OH  . TYR A 1 501 ? 146.141 126.355 150.268 1.00 47.71  ? 501  TYR A OH  1 
ATOM   2755  N N   . SER A 1 502 ? 143.693 132.154 154.071 1.00 51.86  ? 502  SER A N   1 
ATOM   2756  C CA  . SER A 1 502 ? 144.939 132.872 154.359 1.00 51.86  ? 502  SER A CA  1 
ATOM   2757  C C   . SER A 1 502 ? 145.126 134.121 153.508 1.00 51.86  ? 502  SER A C   1 
ATOM   2758  O O   . SER A 1 502 ? 145.906 134.107 152.550 1.00 51.86  ? 502  SER A O   1 
ATOM   2759  C CB  . SER A 1 502 ? 146.163 131.952 154.211 1.00 51.86  ? 502  SER A CB  1 
ATOM   2760  O OG  . SER A 1 502 ? 146.564 131.847 152.854 1.00 51.86  ? 502  SER A OG  1 
ATOM   2761  N N   . PHE A 1 503 ? 144.369 135.175 153.843 1.00 53.16  ? 503  PHE A N   1 
ATOM   2762  C CA  . PHE A 1 503 ? 144.269 136.474 153.172 1.00 53.16  ? 503  PHE A CA  1 
ATOM   2763  C C   . PHE A 1 503 ? 145.556 137.068 152.603 1.00 53.16  ? 503  PHE A C   1 
ATOM   2764  O O   . PHE A 1 503 ? 145.514 137.768 151.587 1.00 53.16  ? 503  PHE A O   1 
ATOM   2765  C CB  . PHE A 1 503 ? 143.688 137.491 154.148 1.00 53.16  ? 503  PHE A CB  1 
ATOM   2766  C CG  . PHE A 1 503 ? 142.216 137.713 153.999 1.00 53.16  ? 503  PHE A CG  1 
ATOM   2767  C CD1 . PHE A 1 503 ? 141.310 136.769 154.456 1.00 53.16  ? 503  PHE A CD1 1 
ATOM   2768  C CD2 . PHE A 1 503 ? 141.735 138.873 153.416 1.00 53.16  ? 503  PHE A CD2 1 
ATOM   2769  C CE1 . PHE A 1 503 ? 139.948 136.974 154.324 1.00 53.16  ? 503  PHE A CE1 1 
ATOM   2770  C CE2 . PHE A 1 503 ? 140.379 139.084 153.282 1.00 53.16  ? 503  PHE A CE2 1 
ATOM   2771  C CZ  . PHE A 1 503 ? 139.484 138.133 153.736 1.00 53.16  ? 503  PHE A CZ  1 
ATOM   2772  N N   . ARG A 1 504 ? 146.693 136.814 153.256 1.00 67.17  ? 504  ARG A N   1 
ATOM   2773  C CA  . ARG A 1 504 ? 147.984 137.322 152.805 1.00 67.17  ? 504  ARG A CA  1 
ATOM   2774  C C   . ARG A 1 504 ? 148.416 136.772 151.450 1.00 67.17  ? 504  ARG A C   1 
ATOM   2775  O O   . ARG A 1 504 ? 149.257 137.394 150.794 1.00 67.17  ? 504  ARG A O   1 
ATOM   2776  C CB  . ARG A 1 504 ? 149.057 137.010 153.852 1.00 67.17  ? 504  ARG A CB  1 
ATOM   2777  C CG  . ARG A 1 504 ? 150.211 138.006 153.887 1.00 67.17  ? 504  ARG A CG  1 
ATOM   2778  C CD  . ARG A 1 504 ? 151.561 137.302 153.869 1.00 67.17  ? 504  ARG A CD  1 
ATOM   2779  N NE  . ARG A 1 504 ? 151.838 136.653 152.589 1.00 67.17  ? 504  ARG A NE  1 
ATOM   2780  C CZ  . ARG A 1 504 ? 152.359 137.265 151.531 1.00 67.17  ? 504  ARG A CZ  1 
ATOM   2781  N NH1 . ARG A 1 504 ? 152.671 138.551 151.591 1.00 67.17  ? 504  ARG A NH1 1 
ATOM   2782  N NH2 . ARG A 1 504 ? 152.573 136.589 150.411 1.00 67.17  ? 504  ARG A NH2 1 
ATOM   2783  N N   . GLN A 1 505 ? 147.876 135.641 151.010 1.00 61.57  ? 505  GLN A N   1 
ATOM   2784  C CA  . GLN A 1 505 ? 148.250 135.089 149.718 1.00 61.57  ? 505  GLN A CA  1 
ATOM   2785  C C   . GLN A 1 505 ? 147.083 134.909 148.760 1.00 61.57  ? 505  GLN A C   1 
ATOM   2786  O O   . GLN A 1 505 ? 147.316 134.669 147.573 1.00 61.57  ? 505  GLN A O   1 
ATOM   2787  C CB  . GLN A 1 505 ? 148.958 133.737 149.898 1.00 61.57  ? 505  GLN A CB  1 
ATOM   2788  C CG  . GLN A 1 505 ? 150.177 133.552 149.006 1.00 61.57  ? 505  GLN A CG  1 
ATOM   2789  C CD  . GLN A 1 505 ? 149.861 132.850 147.704 1.00 61.57  ? 505  GLN A CD  1 
ATOM   2790  O OE1 . GLN A 1 505 ? 148.925 132.057 147.623 1.00 61.57  ? 505  GLN A OE1 1 
ATOM   2791  N NE2 . GLN A 1 505 ? 150.644 133.138 146.673 1.00 61.57  ? 505  GLN A NE2 1 
ATOM   2792  N N   . VAL A 1 506 ? 145.838 135.016 149.227 1.00 53.00  ? 506  VAL A N   1 
ATOM   2793  C CA  . VAL A 1 506 ? 144.716 134.904 148.301 1.00 53.00  ? 506  VAL A CA  1 
ATOM   2794  C C   . VAL A 1 506 ? 144.511 136.227 147.566 1.00 53.00  ? 506  VAL A C   1 
ATOM   2795  O O   . VAL A 1 506 ? 143.945 136.261 146.467 1.00 53.00  ? 506  VAL A O   1 
ATOM   2796  C CB  . VAL A 1 506 ? 143.445 134.431 149.046 1.00 53.00  ? 506  VAL A CB  1 
ATOM   2797  C CG1 . VAL A 1 506 ? 142.855 135.517 149.912 1.00 53.00  ? 506  VAL A CG1 1 
ATOM   2798  C CG2 . VAL A 1 506 ? 142.402 133.872 148.092 1.00 53.00  ? 506  VAL A CG2 1 
ATOM   2799  N N   . GLN A 1 507 ? 144.999 137.332 148.136 1.00 53.12  ? 507  GLN A N   1 
ATOM   2800  C CA  . GLN A 1 507 ? 144.853 138.653 147.527 1.00 53.12  ? 507  GLN A CA  1 
ATOM   2801  C C   . GLN A 1 507 ? 146.096 139.036 146.722 1.00 53.12  ? 507  GLN A C   1 
ATOM   2802  O O   . GLN A 1 507 ? 146.707 140.088 146.903 1.00 53.12  ? 507  GLN A O   1 
ATOM   2803  C CB  . GLN A 1 507 ? 144.526 139.683 148.596 1.00 53.12  ? 507  GLN A CB  1 
ATOM   2804  C CG  . GLN A 1 507 ? 143.037 139.787 148.843 1.00 53.12  ? 507  GLN A CG  1 
ATOM   2805  C CD  . GLN A 1 507 ? 142.681 140.870 149.824 1.00 53.12  ? 507  GLN A CD  1 
ATOM   2806  O OE1 . GLN A 1 507 ? 141.595 140.859 150.404 1.00 53.12  ? 507  GLN A OE1 1 
ATOM   2807  N NE2 . GLN A 1 507 ? 143.597 141.804 150.037 1.00 53.12  ? 507  GLN A NE2 1 
ATOM   2808  N N   . VAL A 1 508 ? 146.470 138.127 145.828 1.00 46.38  ? 508  VAL A N   1 
ATOM   2809  C CA  . VAL A 1 508 ? 147.329 138.442 144.690 1.00 46.38  ? 508  VAL A CA  1 
ATOM   2810  C C   . VAL A 1 508 ? 146.675 138.068 143.372 1.00 46.38  ? 508  VAL A C   1 
ATOM   2811  O O   . VAL A 1 508 ? 146.875 138.772 142.361 1.00 46.38  ? 508  VAL A O   1 
ATOM   2812  C CB  . VAL A 1 508 ? 148.702 137.739 144.865 1.00 46.38  ? 508  VAL A CB  1 
ATOM   2813  C CG1 . VAL A 1 508 ? 149.534 137.652 143.586 1.00 46.38  ? 508  VAL A CG1 1 
ATOM   2814  C CG2 . VAL A 1 508 ? 149.507 138.454 145.934 1.00 46.38  ? 508  VAL A CG2 1 
ATOM   2815  N N   . ILE A 1 509 ? 145.799 137.066 143.388 1.00 41.65  ? 509  ILE A N   1 
ATOM   2816  C CA  . ILE A 1 509 ? 144.851 136.670 142.343 1.00 41.65  ? 509  ILE A CA  1 
ATOM   2817  C C   . ILE A 1 509 ? 144.122 137.849 141.682 1.00 41.65  ? 509  ILE A C   1 
ATOM   2818  O O   . ILE A 1 509 ? 143.980 137.826 140.449 1.00 41.65  ? 509  ILE A O   1 
ATOM   2819  C CB  . ILE A 1 509 ? 143.872 135.628 142.926 1.00 41.65  ? 509  ILE A CB  1 
ATOM   2820  C CG1 . ILE A 1 509 ? 144.626 134.373 143.370 1.00 41.65  ? 509  ILE A CG1 1 
ATOM   2821  C CG2 . ILE A 1 509 ? 142.770 135.259 141.963 1.00 41.65  ? 509  ILE A CG2 1 
ATOM   2822  C CD1 . ILE A 1 509 ? 145.062 133.461 142.234 1.00 41.65  ? 509  ILE A CD1 1 
ATOM   2823  N N   . PRO A 1 510 ? 143.658 138.905 142.390 1.00 37.37  ? 510  PRO A N   1 
ATOM   2824  C CA  . PRO A 1 510 ? 143.241 140.108 141.638 1.00 37.37  ? 510  PRO A CA  1 
ATOM   2825  C C   . PRO A 1 510 ? 144.381 140.789 140.907 1.00 37.37  ? 510  PRO A C   1 
ATOM   2826  O O   . PRO A 1 510 ? 144.331 140.928 139.682 1.00 37.37  ? 510  PRO A O   1 
ATOM   2827  C CB  . PRO A 1 510 ? 142.646 141.014 142.722 1.00 37.37  ? 510  PRO A CB  1 
ATOM   2828  C CG  . PRO A 1 510 ? 142.236 140.109 143.780 1.00 37.37  ? 510  PRO A CG  1 
ATOM   2829  C CD  . PRO A 1 510 ? 143.287 139.058 143.815 1.00 37.37  ? 510  PRO A CD  1 
ATOM   2830  N N   . GLY A 1 511 ? 145.436 141.169 141.615 1.00 35.65  ? 511  GLY A N   1 
ATOM   2831  C CA  . GLY A 1 511 ? 146.558 141.863 141.023 1.00 35.65  ? 511  GLY A CA  1 
ATOM   2832  C C   . GLY A 1 511 ? 147.442 141.054 140.103 1.00 35.65  ? 511  GLY A C   1 
ATOM   2833  O O   . GLY A 1 511 ? 148.398 141.601 139.551 1.00 35.65  ? 511  GLY A O   1 
ATOM   2834  N N   . LEU A 1 512 ? 147.163 139.763 139.924 1.00 36.92  ? 512  LEU A N   1 
ATOM   2835  C CA  . LEU A 1 512 ? 147.889 138.922 138.985 1.00 36.92  ? 512  LEU A CA  1 
ATOM   2836  C C   . LEU A 1 512 ? 147.110 138.675 137.705 1.00 36.92  ? 512  LEU A C   1 
ATOM   2837  O O   . LEU A 1 512 ? 147.722 138.519 136.644 1.00 36.92  ? 512  LEU A O   1 
ATOM   2838  C CB  . LEU A 1 512 ? 148.226 137.571 139.636 1.00 36.92  ? 512  LEU A CB  1 
ATOM   2839  C CG  . LEU A 1 512 ? 149.151 136.593 138.922 1.00 36.92  ? 512  LEU A CG  1 
ATOM   2840  C CD1 . LEU A 1 512 ? 150.543 137.184 138.830 1.00 36.92  ? 512  LEU A CD1 1 
ATOM   2841  C CD2 . LEU A 1 512 ? 149.175 135.264 139.646 1.00 36.92  ? 512  LEU A CD2 1 
ATOM   2842  N N   . LEU A 1 513 ? 145.779 138.634 137.790 1.00 29.84  ? 513  LEU A N   1 
ATOM   2843  C CA  . LEU A 1 513 ? 144.933 138.594 136.605 1.00 29.84  ? 513  LEU A CA  1 
ATOM   2844  C C   . LEU A 1 513 ? 145.119 139.841 135.762 1.00 29.84  ? 513  LEU A C   1 
ATOM   2845  O O   . LEU A 1 513 ? 145.077 139.770 134.530 1.00 29.84  ? 513  LEU A O   1 
ATOM   2846  C CB  . LEU A 1 513 ? 143.477 138.443 137.030 1.00 29.84  ? 513  LEU A CB  1 
ATOM   2847  C CG  . LEU A 1 513 ? 142.394 138.403 135.971 1.00 29.84  ? 513  LEU A CG  1 
ATOM   2848  C CD1 . LEU A 1 513 ? 142.713 137.367 134.926 1.00 29.84  ? 513  LEU A CD1 1 
ATOM   2849  C CD2 . LEU A 1 513 ? 141.099 138.090 136.660 1.00 29.84  ? 513  LEU A CD2 1 
ATOM   2850  N N   . LEU A 1 514 ? 145.316 140.984 136.414 1.00 29.90  ? 514  LEU A N   1 
ATOM   2851  C CA  . LEU A 1 514 ? 145.788 142.176 135.725 1.00 29.90  ? 514  LEU A CA  1 
ATOM   2852  C C   . LEU A 1 514 ? 147.156 141.933 135.109 1.00 29.90  ? 514  LEU A C   1 
ATOM   2853  O O   . LEU A 1 514 ? 147.396 142.282 133.948 1.00 29.90  ? 514  LEU A O   1 
ATOM   2854  C CB  . LEU A 1 514 ? 145.829 143.341 136.710 1.00 29.90  ? 514  LEU A CB  1 
ATOM   2855  C CG  . LEU A 1 514 ? 146.245 144.728 136.243 1.00 29.90  ? 514  LEU A CG  1 
ATOM   2856  C CD1 . LEU A 1 514 ? 145.364 145.686 136.928 1.00 29.90  ? 514  LEU A CD1 1 
ATOM   2857  C CD2 . LEU A 1 514 ? 147.683 145.049 136.614 1.00 29.90  ? 514  LEU A CD2 1 
ATOM   2858  N N   . LEU A 1 515 ? 148.063 141.318 135.873 1.00 36.25  ? 515  LEU A N   1 
ATOM   2859  C CA  . LEU A 1 515 ? 149.415 141.079 135.389 1.00 36.25  ? 515  LEU A CA  1 
ATOM   2860  C C   . LEU A 1 515 ? 149.451 140.023 134.300 1.00 36.25  ? 515  LEU A C   1 
ATOM   2861  O O   . LEU A 1 515 ? 150.309 140.095 133.419 1.00 36.25  ? 515  LEU A O   1 
ATOM   2862  C CB  . LEU A 1 515 ? 150.326 140.677 136.549 1.00 36.25  ? 515  LEU A CB  1 
ATOM   2863  C CG  . LEU A 1 515 ? 151.827 140.580 136.261 1.00 36.25  ? 515  LEU A CG  1 
ATOM   2864  C CD1 . LEU A 1 515 ? 152.335 141.854 135.610 1.00 36.25  ? 515  LEU A CD1 1 
ATOM   2865  C CD2 . LEU A 1 515 ? 152.598 140.277 137.525 1.00 36.25  ? 515  LEU A CD2 1 
ATOM   2866  N N   . GLY A 1 516 ? 148.533 139.062 134.326 1.00 35.22  ? 516  GLY A N   1 
ATOM   2867  C CA  . GLY A 1 516 ? 148.430 138.108 133.239 1.00 35.22  ? 516  GLY A CA  1 
ATOM   2868  C C   . GLY A 1 516 ? 147.977 138.766 131.951 1.00 35.22  ? 516  GLY A C   1 
ATOM   2869  O O   . GLY A 1 516 ? 148.535 138.513 130.881 1.00 35.22  ? 516  GLY A O   1 
ATOM   2870  N N   . PHE A 1 517 ? 146.975 139.639 132.059 1.00 26.70  ? 517  PHE A N   1 
ATOM   2871  C CA  . PHE A 1 517 ? 146.462 140.350 130.898 1.00 26.70  ? 517  PHE A CA  1 
ATOM   2872  C C   . PHE A 1 517 ? 147.413 141.422 130.407 1.00 26.70  ? 517  PHE A C   1 
ATOM   2873  O O   . PHE A 1 517 ? 147.347 141.795 129.234 1.00 26.70  ? 517  PHE A O   1 
ATOM   2874  C CB  . PHE A 1 517 ? 145.117 140.977 131.224 1.00 26.70  ? 517  PHE A CB  1 
ATOM   2875  C CG  . PHE A 1 517 ? 143.968 140.109 130.881 1.00 26.70  ? 517  PHE A CG  1 
ATOM   2876  C CD1 . PHE A 1 517 ? 143.583 139.950 129.572 1.00 26.70  ? 517  PHE A CD1 1 
ATOM   2877  C CD2 . PHE A 1 517 ? 143.281 139.436 131.862 1.00 26.70  ? 517  PHE A CD2 1 
ATOM   2878  C CE1 . PHE A 1 517 ? 142.531 139.143 129.256 1.00 26.70  ? 517  PHE A CE1 1 
ATOM   2879  C CE2 . PHE A 1 517 ? 142.231 138.629 131.546 1.00 26.70  ? 517  PHE A CE2 1 
ATOM   2880  C CZ  . PHE A 1 517 ? 141.851 138.487 130.249 1.00 26.70  ? 517  PHE A CZ  1 
ATOM   2881  N N   . LEU A 1 518 ? 148.283 141.934 131.272 1.00 31.40  ? 518  LEU A N   1 
ATOM   2882  C CA  . LEU A 1 518 ? 149.215 142.965 130.844 1.00 31.40  ? 518  LEU A CA  1 
ATOM   2883  C C   . LEU A 1 518 ? 150.282 142.393 129.922 1.00 31.40  ? 518  LEU A C   1 
ATOM   2884  O O   . LEU A 1 518 ? 150.709 143.065 128.978 1.00 31.40  ? 518  LEU A O   1 
ATOM   2885  C CB  . LEU A 1 518 ? 149.845 143.616 132.072 1.00 31.40  ? 518  LEU A CB  1 
ATOM   2886  C CG  . LEU A 1 518 ? 150.299 145.074 132.047 1.00 31.40  ? 518  LEU A CG  1 
ATOM   2887  C CD1 . LEU A 1 518 ? 150.379 145.575 133.475 1.00 31.40  ? 518  LEU A CD1 1 
ATOM   2888  C CD2 . LEU A 1 518 ? 151.635 145.268 131.354 1.00 31.40  ? 518  LEU A CD2 1 
ATOM   2889  N N   . LEU A 1 519 ? 150.707 141.154 130.166 1.00 35.65  ? 519  LEU A N   1 
ATOM   2890  C CA  . LEU A 1 519 ? 151.765 140.528 129.386 1.00 35.65  ? 519  LEU A CA  1 
ATOM   2891  C C   . LEU A 1 519 ? 151.266 139.846 128.125 1.00 35.65  ? 519  LEU A C   1 
ATOM   2892  O O   . LEU A 1 519 ? 152.058 139.652 127.200 1.00 35.65  ? 519  LEU A O   1 
ATOM   2893  C CB  . LEU A 1 519 ? 152.531 139.516 130.242 1.00 35.65  ? 519  LEU A CB  1 
ATOM   2894  C CG  . LEU A 1 519 ? 152.965 140.029 131.611 1.00 35.65  ? 519  LEU A CG  1 
ATOM   2895  C CD1 . LEU A 1 519 ? 153.387 138.888 132.506 1.00 35.65  ? 519  LEU A CD1 1 
ATOM   2896  C CD2 . LEU A 1 519 ? 154.088 141.042 131.466 1.00 35.65  ? 519  LEU A CD2 1 
ATOM   2897  N N   . ILE A 1 520 ? 149.990 139.453 128.073 1.00 35.37  ? 520  ILE A N   1 
ATOM   2898  C CA  . ILE A 1 520 ? 149.392 139.016 126.813 1.00 35.37  ? 520  ILE A CA  1 
ATOM   2899  C C   . ILE A 1 520 ? 149.369 140.137 125.788 1.00 35.37  ? 520  ILE A C   1 
ATOM   2900  O O   . ILE A 1 520 ? 149.674 139.899 124.611 1.00 35.37  ? 520  ILE A O   1 
ATOM   2901  C CB  . ILE A 1 520 ? 147.974 138.470 127.075 1.00 35.37  ? 520  ILE A CB  1 
ATOM   2902  C CG1 . ILE A 1 520 ? 148.031 137.239 127.972 1.00 35.37  ? 520  ILE A CG1 1 
ATOM   2903  C CG2 . ILE A 1 520 ? 147.264 138.103 125.784 1.00 35.37  ? 520  ILE A CG2 1 
ATOM   2904  C CD1 . ILE A 1 520 ? 146.682 136.678 128.321 1.00 35.37  ? 520  ILE A CD1 1 
ATOM   2905  N N   . LEU A 1 521 ? 149.066 141.360 126.219 1.00 39.17  ? 521  LEU A N   1 
ATOM   2906  C CA  . LEU A 1 521 ? 149.066 142.530 125.356 1.00 39.17  ? 521  LEU A CA  1 
ATOM   2907  C C   . LEU A 1 521 ? 150.436 142.843 124.776 1.00 39.17  ? 521  LEU A C   1 
ATOM   2908  O O   . LEU A 1 521 ? 150.517 143.306 123.634 1.00 39.17  ? 521  LEU A O   1 
ATOM   2909  C CB  . LEU A 1 521 ? 148.550 143.746 126.131 1.00 39.17  ? 521  LEU A CB  1 
ATOM   2910  C CG  . LEU A 1 521 ? 148.202 145.018 125.357 1.00 39.17  ? 521  LEU A CG  1 
ATOM   2911  C CD1 . LEU A 1 521 ? 147.146 144.741 124.322 1.00 39.17  ? 521  LEU A CD1 1 
ATOM   2912  C CD2 . LEU A 1 521 ? 147.727 146.090 126.312 1.00 39.17  ? 521  LEU A CD2 1 
ATOM   2913  N N   . ILE A 1 522 ? 151.508 142.584 125.517 1.00 41.25  ? 522  ILE A N   1 
ATOM   2914  C CA  . ILE A 1 522 ? 152.858 142.857 125.050 1.00 41.25  ? 522  ILE A CA  1 
ATOM   2915  C C   . ILE A 1 522 ? 153.602 141.569 124.699 1.00 41.25  ? 522  ILE A C   1 
ATOM   2916  O O   . ILE A 1 522 ? 154.813 141.588 124.517 1.00 41.25  ? 522  ILE A O   1 
ATOM   2917  C CB  . ILE A 1 522 ? 153.638 143.691 126.082 1.00 41.25  ? 522  ILE A CB  1 
ATOM   2918  C CG1 . ILE A 1 522 ? 153.796 142.904 127.383 1.00 41.25  ? 522  ILE A CG1 1 
ATOM   2919  C CG2 . ILE A 1 522 ? 152.923 144.999 126.335 1.00 41.25  ? 522  ILE A CG2 1 
ATOM   2920  C CD1 . ILE A 1 522 ? 154.432 143.680 128.516 1.00 41.25  ? 522  ILE A CD1 1 
ATOM   2921  N N   . CYS A 1 523 ? 152.881 140.451 124.611 1.00 43.71  ? 523  CYS A N   1 
ATOM   2922  C CA  . CYS A 1 523 ? 153.467 139.163 124.234 1.00 43.71  ? 523  CYS A CA  1 
ATOM   2923  C C   . CYS A 1 523 ? 153.978 139.208 122.802 1.00 43.71  ? 523  CYS A C   1 
ATOM   2924  O O   . CYS A 1 523 ? 153.191 139.463 121.882 1.00 43.71  ? 523  CYS A O   1 
ATOM   2925  C CB  . CYS A 1 523 ? 152.444 138.047 124.379 1.00 43.71  ? 523  CYS A CB  1 
ATOM   2926  S SG  . CYS A 1 523 ? 152.902 136.524 123.534 1.00 43.71  ? 523  CYS A SG  1 
ATOM   2927  N N   . PRO A 1 524 ? 155.265 138.974 122.563 1.00 43.22  ? 524  PRO A N   1 
ATOM   2928  C CA  . PRO A 1 524 ? 155.833 139.185 121.227 1.00 43.22  ? 524  PRO A CA  1 
ATOM   2929  C C   . PRO A 1 524 ? 155.901 137.953 120.337 1.00 43.22  ? 524  PRO A C   1 
ATOM   2930  O O   . PRO A 1 524 ? 156.586 138.018 119.312 1.00 43.22  ? 524  PRO A O   1 
ATOM   2931  C CB  . PRO A 1 524 ? 157.248 139.665 121.564 1.00 43.22  ? 524  PRO A CB  1 
ATOM   2932  C CG  . PRO A 1 524 ? 157.593 138.911 122.806 1.00 43.22  ? 524  PRO A CG  1 
ATOM   2933  C CD  . PRO A 1 524 ? 156.307 138.617 123.541 1.00 43.22  ? 524  PRO A CD  1 
ATOM   2934  N N   . LEU A 1 525 ? 155.255 136.834 120.676 1.00 41.22  ? 525  LEU A N   1 
ATOM   2935  C CA  . LEU A 1 525 ? 155.634 135.636 119.941 1.00 41.22  ? 525  LEU A CA  1 
ATOM   2936  C C   . LEU A 1 525 ? 154.909 135.484 118.608 1.00 41.22  ? 525  LEU A C   1 
ATOM   2937  O O   . LEU A 1 525 ? 155.436 135.935 117.586 1.00 41.22  ? 525  LEU A O   1 
ATOM   2938  C CB  . LEU A 1 525 ? 155.384 134.416 120.830 1.00 41.22  ? 525  LEU A CB  1 
ATOM   2939  C CG  . LEU A 1 525 ? 155.865 134.607 122.275 1.00 41.22  ? 525  LEU A CG  1 
ATOM   2940  C CD1 . LEU A 1 525 ? 155.317 133.543 123.197 1.00 41.22  ? 525  LEU A CD1 1 
ATOM   2941  C CD2 . LEU A 1 525 ? 157.380 134.613 122.337 1.00 41.22  ? 525  LEU A CD2 1 
ATOM   2942  N N   . ASN A 1 526 ? 153.707 134.895 118.595 1.00 33.10  ? 526  ASN A N   1 
ATOM   2943  C CA  . ASN A 1 526 ? 152.767 135.043 117.485 1.00 33.10  ? 526  ASN A CA  1 
ATOM   2944  C C   . ASN A 1 526 ? 151.334 134.739 117.898 1.00 33.10  ? 526  ASN A C   1 
ATOM   2945  O O   . ASN A 1 526 ? 150.438 134.738 117.049 1.00 33.10  ? 526  ASN A O   1 
ATOM   2946  C CB  . ASN A 1 526 ? 153.135 134.152 116.294 1.00 33.10  ? 526  ASN A CB  1 
ATOM   2947  C CG  . ASN A 1 526 ? 152.735 134.772 114.963 1.00 33.10  ? 526  ASN A CG  1 
ATOM   2948  O OD1 . ASN A 1 526 ? 152.155 135.855 114.921 1.00 33.10  ? 526  ASN A OD1 1 
ATOM   2949  N ND2 . ASN A 1 526 ? 153.044 134.087 113.872 1.00 33.10  ? 526  ASN A ND2 1 
ATOM   2950  N N   . ILE A 1 527 ? 151.110 134.438 119.175 1.00 34.87  ? 527  ILE A N   1 
ATOM   2951  C CA  . ILE A 1 527 ? 149.928 133.664 119.552 1.00 34.87  ? 527  ILE A CA  1 
ATOM   2952  C C   . ILE A 1 527 ? 148.670 134.522 119.515 1.00 34.87  ? 527  ILE A C   1 
ATOM   2953  O O   . ILE A 1 527 ? 147.747 134.274 118.730 1.00 34.87  ? 527  ILE A O   1 
ATOM   2954  C CB  . ILE A 1 527 ? 150.114 133.030 120.941 1.00 34.87  ? 527  ILE A CB  1 
ATOM   2955  C CG1 . ILE A 1 527 ? 151.558 132.591 121.149 1.00 34.87  ? 527  ILE A CG1 1 
ATOM   2956  C CG2 . ILE A 1 527 ? 149.185 131.838 121.099 1.00 34.87  ? 527  ILE A CG2 1 
ATOM   2957  C CD1 . ILE A 1 527 ? 151.872 132.295 122.588 1.00 34.87  ? 527  ILE A CD1 1 
ATOM   2958  N N   . PHE A 1 528 ? 148.618 135.546 120.363 1.00 32.36  ? 528  PHE A N   1 
ATOM   2959  C CA  . PHE A 1 528 ? 147.388 136.302 120.579 1.00 32.36  ? 528  PHE A CA  1 
ATOM   2960  C C   . PHE A 1 528 ? 147.381 137.546 119.694 1.00 32.36  ? 528  PHE A C   1 
ATOM   2961  O O   . PHE A 1 528 ? 147.540 138.674 120.156 1.00 32.36  ? 528  PHE A O   1 
ATOM   2962  C CB  . PHE A 1 528 ? 147.247 136.659 122.049 1.00 32.36  ? 528  PHE A CB  1 
ATOM   2963  C CG  . PHE A 1 528 ? 147.357 135.482 122.959 1.00 32.36  ? 528  PHE A CG  1 
ATOM   2964  C CD1 . PHE A 1 528 ? 146.372 134.509 122.969 1.00 32.36  ? 528  PHE A CD1 1 
ATOM   2965  C CD2 . PHE A 1 528 ? 148.449 135.340 123.793 1.00 32.36  ? 528  PHE A CD2 1 
ATOM   2966  C CE1 . PHE A 1 528 ? 146.469 133.420 123.805 1.00 32.36  ? 528  PHE A CE1 1 
ATOM   2967  C CE2 . PHE A 1 528 ? 148.553 134.256 124.631 1.00 32.36  ? 528  PHE A CE2 1 
ATOM   2968  C CZ  . PHE A 1 528 ? 147.560 133.294 124.639 1.00 32.36  ? 528  PHE A CZ  1 
ATOM   2969  N N   . TYR A 1 529 ? 147.204 137.291 118.394 1.00 25.38  ? 529  TYR A N   1 
ATOM   2970  C CA  . TYR A 1 529 ? 146.987 138.311 117.366 1.00 25.38  ? 529  TYR A CA  1 
ATOM   2971  C C   . TYR A 1 529 ? 148.110 139.342 117.310 1.00 25.38  ? 529  TYR A C   1 
ATOM   2972  O O   . TYR A 1 529 ? 147.868 140.544 117.373 1.00 25.38  ? 529  TYR A O   1 
ATOM   2973  C CB  . TYR A 1 529 ? 145.651 139.021 117.562 1.00 25.38  ? 529  TYR A CB  1 
ATOM   2974  C CG  . TYR A 1 529 ? 144.424 138.194 117.350 1.00 25.38  ? 529  TYR A CG  1 
ATOM   2975  C CD1 . TYR A 1 529 ? 143.739 138.238 116.150 1.00 25.38  ? 529  TYR A CD1 1 
ATOM   2976  C CD2 . TYR A 1 529 ? 143.920 137.408 118.366 1.00 25.38  ? 529  TYR A CD2 1 
ATOM   2977  C CE1 . TYR A 1 529 ? 142.600 137.501 115.962 1.00 25.38  ? 529  TYR A CE1 1 
ATOM   2978  C CE2 . TYR A 1 529 ? 142.785 136.669 118.187 1.00 25.38  ? 529  TYR A CE2 1 
ATOM   2979  C CZ  . TYR A 1 529 ? 142.132 136.720 116.987 1.00 25.38  ? 529  TYR A CZ  1 
ATOM   2980  O OH  . TYR A 1 529 ? 140.999 135.975 116.819 1.00 25.38  ? 529  TYR A OH  1 
ATOM   2981  N N   . LYS A 1 530 ? 149.347 138.878 117.212 1.00 34.61  ? 530  LYS A N   1 
ATOM   2982  C CA  . LYS A 1 530 ? 150.414 139.808 116.886 1.00 34.61  ? 530  LYS A CA  1 
ATOM   2983  C C   . LYS A 1 530 ? 150.227 140.271 115.440 1.00 34.61  ? 530  LYS A C   1 
ATOM   2984  O O   . LYS A 1 530 ? 149.604 139.576 114.631 1.00 34.61  ? 530  LYS A O   1 
ATOM   2985  C CB  . LYS A 1 530 ? 151.775 139.146 117.112 1.00 34.61  ? 530  LYS A CB  1 
ATOM   2986  C CG  . LYS A 1 530 ? 152.982 140.071 117.039 1.00 34.61  ? 530  LYS A CG  1 
ATOM   2987  C CD  . LYS A 1 530 ? 154.269 139.357 117.370 1.00 34.61  ? 530  LYS A CD  1 
ATOM   2988  C CE  . LYS A 1 530 ? 155.462 140.240 117.067 1.00 34.61  ? 530  LYS A CE  1 
ATOM   2989  N NZ  . LYS A 1 530 ? 155.465 141.449 117.927 1.00 34.61  ? 530  LYS A NZ  1 
ATOM   2990  N N   . SER A 1 531 ? 150.757 141.468 115.139 1.00 37.54  ? 531  SER A N   1 
ATOM   2991  C CA  . SER A 1 531 ? 150.536 142.345 113.980 1.00 37.54  ? 531  SER A CA  1 
ATOM   2992  C C   . SER A 1 531 ? 149.184 143.035 114.021 1.00 37.54  ? 531  SER A C   1 
ATOM   2993  O O   . SER A 1 531 ? 148.793 143.669 113.036 1.00 37.54  ? 531  SER A O   1 
ATOM   2994  C CB  . SER A 1 531 ? 150.699 141.660 112.615 1.00 37.54  ? 531  SER A CB  1 
ATOM   2995  O OG  . SER A 1 531 ? 149.467 141.106 112.192 1.00 37.54  ? 531  SER A OG  1 
ATOM   2996  N N   . SER A 1 532 ? 148.452 142.923 115.126 1.00 25.57  ? 532  SER A N   1 
ATOM   2997  C CA  . SER A 1 532 ? 147.397 143.878 115.432 1.00 25.57  ? 532  SER A CA  1 
ATOM   2998  C C   . SER A 1 532 ? 147.386 144.207 116.913 1.00 25.57  ? 532  SER A C   1 
ATOM   2999  O O   . SER A 1 532 ? 146.540 144.986 117.357 1.00 25.57  ? 532  SER A O   1 
ATOM   3000  C CB  . SER A 1 532 ? 146.032 143.360 115.010 1.00 25.57  ? 532  SER A CB  1 
ATOM   3001  O OG  . SER A 1 532 ? 145.389 142.674 116.068 1.00 25.57  ? 532  SER A OG  1 
ATOM   3002  N N   . ARG A 1 533 ? 148.298 143.637 117.677 1.00 31.94  ? 533  ARG A N   1 
ATOM   3003  C CA  . ARG A 1 533 ? 148.461 143.932 119.082 1.00 31.94  ? 533  ARG A CA  1 
ATOM   3004  C C   . ARG A 1 533 ? 149.769 144.643 119.351 1.00 31.94  ? 533  ARG A C   1 
ATOM   3005  O O   . ARG A 1 533 ? 149.957 145.170 120.449 1.00 31.94  ? 533  ARG A O   1 
ATOM   3006  C CB  . ARG A 1 533 ? 148.394 142.629 119.885 1.00 31.94  ? 533  ARG A CB  1 
ATOM   3007  C CG  . ARG A 1 533 ? 148.161 142.715 121.366 1.00 31.94  ? 533  ARG A CG  1 
ATOM   3008  C CD  . ARG A 1 533 ? 148.224 141.324 121.978 1.00 31.94  ? 533  ARG A CD  1 
ATOM   3009  N NE  . ARG A 1 533 ? 148.925 140.371 121.121 1.00 31.94  ? 533  ARG A NE  1 
ATOM   3010  C CZ  . ARG A 1 533 ? 150.186 139.996 121.286 1.00 31.94  ? 533  ARG A CZ  1 
ATOM   3011  N NH1 . ARG A 1 533 ? 150.896 140.488 122.286 1.00 31.94  ? 533  ARG A NH1 1 
ATOM   3012  N NH2 . ARG A 1 533 ? 150.736 139.136 120.444 1.00 31.94  ? 533  ARG A NH2 1 
ATOM   3013  N N   . TYR A 1 534 ? 150.673 144.678 118.378 1.00 37.64  ? 534  TYR A N   1 
ATOM   3014  C CA  . TYR A 1 534 ? 151.802 145.590 118.423 1.00 37.64  ? 534  TYR A CA  1 
ATOM   3015  C C   . TYR A 1 534 ? 151.569 146.829 117.576 1.00 37.64  ? 534  TYR A C   1 
ATOM   3016  O O   . TYR A 1 534 ? 152.303 147.811 117.724 1.00 37.64  ? 534  TYR A O   1 
ATOM   3017  C CB  . TYR A 1 534 ? 153.085 144.877 117.986 1.00 37.64  ? 534  TYR A CB  1 
ATOM   3018  C CG  . TYR A 1 534 ? 153.812 144.249 119.151 1.00 37.64  ? 534  TYR A CG  1 
ATOM   3019  C CD1 . TYR A 1 534 ? 155.026 144.755 119.597 1.00 37.64  ? 534  TYR A CD1 1 
ATOM   3020  C CD2 . TYR A 1 534 ? 153.263 143.169 119.827 1.00 37.64  ? 534  TYR A CD2 1 
ATOM   3021  C CE1 . TYR A 1 534 ? 155.678 144.189 120.674 1.00 37.64  ? 534  TYR A CE1 1 
ATOM   3022  C CE2 . TYR A 1 534 ? 153.906 142.597 120.902 1.00 37.64  ? 534  TYR A CE2 1 
ATOM   3023  C CZ  . TYR A 1 534 ? 155.109 143.109 121.321 1.00 37.64  ? 534  TYR A CZ  1 
ATOM   3024  O OH  . TYR A 1 534 ? 155.742 142.530 122.395 1.00 37.64  ? 534  TYR A OH  1 
ATOM   3025  N N   . ARG A 1 535 ? 150.567 146.806 116.695 1.00 28.88  ? 535  ARG A N   1 
ATOM   3026  C CA  . ARG A 1 535 ? 150.095 148.046 116.089 1.00 28.88  ? 535  ARG A CA  1 
ATOM   3027  C C   . ARG A 1 535 ? 149.340 148.886 117.107 1.00 28.88  ? 535  ARG A C   1 
ATOM   3028  O O   . ARG A 1 535 ? 149.380 150.117 117.063 1.00 28.88  ? 535  ARG A O   1 
ATOM   3029  C CB  . ARG A 1 535 ? 149.210 147.748 114.883 1.00 28.88  ? 535  ARG A CB  1 
ATOM   3030  C CG  . ARG A 1 535 ? 148.837 148.968 114.077 1.00 28.88  ? 535  ARG A CG  1 
ATOM   3031  C CD  . ARG A 1 535 ? 148.035 148.588 112.856 1.00 28.88  ? 535  ARG A CD  1 
ATOM   3032  N NE  . ARG A 1 535 ? 147.622 149.765 112.100 1.00 28.88  ? 535  ARG A NE  1 
ATOM   3033  C CZ  . ARG A 1 535 ? 148.354 150.334 111.151 1.00 28.88  ? 535  ARG A CZ  1 
ATOM   3034  N NH1 . ARG A 1 535 ? 149.535 149.827 110.833 1.00 28.88  ? 535  ARG A NH1 1 
ATOM   3035  N NH2 . ARG A 1 535 ? 147.907 151.404 110.516 1.00 28.88  ? 535  ARG A NH2 1 
ATOM   3036  N N   . LEU A 1 536 ? 148.646 148.237 118.038 1.00 21.78  ? 536  LEU A N   1 
ATOM   3037  C CA  . LEU A 1 536 ? 147.944 148.972 119.078 1.00 21.78  ? 536  LEU A CA  1 
ATOM   3038  C C   . LEU A 1 536 ? 148.901 149.581 120.092 1.00 21.78  ? 536  LEU A C   1 
ATOM   3039  O O   . LEU A 1 536 ? 148.526 150.536 120.772 1.00 21.78  ? 536  LEU A O   1 
ATOM   3040  C CB  . LEU A 1 536 ? 146.929 148.052 119.758 1.00 21.78  ? 536  LEU A CB  1 
ATOM   3041  C CG  . LEU A 1 536 ? 145.840 148.566 120.689 1.00 21.78  ? 536  LEU A CG  1 
ATOM   3042  C CD1 . LEU A 1 536 ? 144.641 147.677 120.512 1.00 21.78  ? 536  LEU A CD1 1 
ATOM   3043  C CD2 . LEU A 1 536 ? 146.277 148.511 122.120 1.00 21.78  ? 536  LEU A CD2 1 
ATOM   3044  N N   . ILE A 1 537 ? 150.129 149.067 120.211 1.00 23.28  ? 537  ILE A N   1 
ATOM   3045  C CA  . ILE A 1 537 ? 151.135 149.761 121.010 1.00 23.28  ? 537  ILE A CA  1 
ATOM   3046  C C   . ILE A 1 537 ? 151.953 150.701 120.135 1.00 23.28  ? 537  ILE A C   1 
ATOM   3047  O O   . ILE A 1 537 ? 152.808 151.439 120.645 1.00 23.28  ? 537  ILE A O   1 
ATOM   3048  C CB  . ILE A 1 537 ? 152.031 148.768 121.782 1.00 23.28  ? 537  ILE A CB  1 
ATOM   3049  C CG1 . ILE A 1 537 ? 151.232 147.546 122.225 1.00 23.28  ? 537  ILE A CG1 1 
ATOM   3050  C CG2 . ILE A 1 537 ? 152.596 149.394 123.062 1.00 23.28  ? 537  ILE A CG2 1 
ATOM   3051  C CD1 . ILE A 1 537 ? 150.193 147.804 123.311 1.00 23.28  ? 537  ILE A CD1 1 
ATOM   3052  N N   . SER A 1 538 ? 151.706 150.721 118.831 1.00 26.69  ? 538  SER A N   1 
ATOM   3053  C CA  . SER A 1 538 ? 152.161 151.818 117.990 1.00 26.69  ? 538  SER A CA  1 
ATOM   3054  C C   . SER A 1 538 ? 151.204 152.997 118.029 1.00 26.69  ? 538  SER A C   1 
ATOM   3055  O O   . SER A 1 538 ? 151.480 154.027 117.410 1.00 26.69  ? 538  SER A O   1 
ATOM   3056  C CB  . SER A 1 538 ? 152.348 151.348 116.547 1.00 26.69  ? 538  SER A CB  1 
ATOM   3057  O OG  . SER A 1 538 ? 152.655 152.434 115.694 1.00 26.69  ? 538  SER A OG  1 
ATOM   3058  N N   . VAL A 1 539 ? 150.091 152.868 118.750 1.00 25.26  ? 539  VAL A N   1 
ATOM   3059  C CA  . VAL A 1 539 ? 149.081 153.911 118.861 1.00 25.26  ? 539  VAL A CA  1 
ATOM   3060  C C   . VAL A 1 539 ? 149.118 154.570 120.233 1.00 25.26  ? 539  VAL A C   1 
ATOM   3061  O O   . VAL A 1 539 ? 149.177 155.794 120.338 1.00 25.26  ? 539  VAL A O   1 
ATOM   3062  C CB  . VAL A 1 539 ? 147.674 153.361 118.555 1.00 25.26  ? 539  VAL A CB  1 
ATOM   3063  C CG1 . VAL A 1 539 ? 146.656 154.411 118.776 1.00 25.26  ? 539  VAL A CG1 1 
ATOM   3064  C CG2 . VAL A 1 539 ? 147.602 152.898 117.129 1.00 25.26  ? 539  VAL A CG2 1 
ATOM   3065  N N   . ILE A 1 540 ? 149.183 153.769 121.296 1.00 23.26  ? 540  ILE A N   1 
ATOM   3066  C CA  . ILE A 1 540 ? 149.215 154.306 122.654 1.00 23.26  ? 540  ILE A CA  1 
ATOM   3067  C C   . ILE A 1 540 ? 150.660 154.594 123.051 1.00 23.26  ? 540  ILE A C   1 
ATOM   3068  O O   . ILE A 1 540 ? 150.969 154.830 124.222 1.00 23.26  ? 540  ILE A O   1 
ATOM   3069  C CB  . ILE A 1 540 ? 148.521 153.358 123.648 1.00 23.26  ? 540  ILE A CB  1 
ATOM   3070  C CG1 . ILE A 1 540 ? 147.343 152.682 122.968 1.00 23.26  ? 540  ILE A CG1 1 
ATOM   3071  C CG2 . ILE A 1 540 ? 147.939 154.124 124.818 1.00 23.26  ? 540  ILE A CG2 1 
ATOM   3072  C CD1 . ILE A 1 540 ? 146.542 151.785 123.869 1.00 23.26  ? 540  ILE A CD1 1 
ATOM   3073  N N   . ARG A 1 541 ? 151.566 154.564 122.083 1.00 38.98  ? 541  ARG A N   1 
ATOM   3074  C CA  . ARG A 1 541 ? 152.865 155.188 122.263 1.00 38.98  ? 541  ARG A CA  1 
ATOM   3075  C C   . ARG A 1 541 ? 152.865 156.627 121.778 1.00 38.98  ? 541  ARG A C   1 
ATOM   3076  O O   . ARG A 1 541 ? 153.492 157.485 122.408 1.00 38.98  ? 541  ARG A O   1 
ATOM   3077  C CB  . ARG A 1 541 ? 153.937 154.382 121.531 1.00 38.98  ? 541  ARG A CB  1 
ATOM   3078  C CG  . ARG A 1 541 ? 155.345 154.904 121.672 1.00 38.98  ? 541  ARG A CG  1 
ATOM   3079  C CD  . ARG A 1 541 ? 156.301 153.969 120.967 1.00 38.98  ? 541  ARG A CD  1 
ATOM   3080  N NE  . ARG A 1 541 ? 155.964 153.827 119.556 1.00 38.98  ? 541  ARG A NE  1 
ATOM   3081  C CZ  . ARG A 1 541 ? 156.366 154.658 118.605 1.00 38.98  ? 541  ARG A CZ  1 
ATOM   3082  N NH1 . ARG A 1 541 ? 157.138 155.692 118.907 1.00 38.98  ? 541  ARG A NH1 1 
ATOM   3083  N NH2 . ARG A 1 541 ? 156.005 154.449 117.349 1.00 38.98  ? 541  ARG A NH2 1 
ATOM   3084  N N   . ASN A 1 542 ? 152.147 156.921 120.693 1.00 35.87  ? 542  ASN A N   1 
ATOM   3085  C CA  . ASN A 1 542 ? 152.062 158.298 120.227 1.00 35.87  ? 542  ASN A CA  1 
ATOM   3086  C C   . ASN A 1 542 ? 151.199 159.155 121.139 1.00 35.87  ? 542  ASN A C   1 
ATOM   3087  O O   . ASN A 1 542 ? 151.443 160.356 121.265 1.00 35.87  ? 542  ASN A O   1 
ATOM   3088  C CB  . ASN A 1 542 ? 151.496 158.366 118.811 1.00 35.87  ? 542  ASN A CB  1 
ATOM   3089  C CG  . ASN A 1 542 ? 152.199 157.449 117.844 1.00 35.87  ? 542  ASN A CG  1 
ATOM   3090  O OD1 . ASN A 1 542 ? 151.578 156.899 116.940 1.00 35.87  ? 542  ASN A OD1 1 
ATOM   3091  N ND2 . ASN A 1 542 ? 153.503 157.289 118.015 1.00 35.87  ? 542  ASN A ND2 1 
ATOM   3092  N N   . ILE A 1 543 ? 150.188 158.568 121.771 1.00 30.31  ? 543  ILE A N   1 
ATOM   3093  C CA  . ILE A 1 543 ? 149.189 159.368 122.471 1.00 30.31  ? 543  ILE A CA  1 
ATOM   3094  C C   . ILE A 1 543 ? 149.728 159.843 123.816 1.00 30.31  ? 543  ILE A C   1 
ATOM   3095  O O   . ILE A 1 543 ? 149.479 160.979 124.234 1.00 30.31  ? 543  ILE A O   1 
ATOM   3096  C CB  . ILE A 1 543 ? 147.884 158.565 122.611 1.00 30.31  ? 543  ILE A CB  1 
ATOM   3097  C CG1 . ILE A 1 543 ? 147.283 158.316 121.238 1.00 30.31  ? 543  ILE A CG1 1 
ATOM   3098  C CG2 . ILE A 1 543 ? 146.862 159.288 123.428 1.00 30.31  ? 543  ILE A CG2 1 
ATOM   3099  C CD1 . ILE A 1 543 ? 146.336 157.186 121.226 1.00 30.31  ? 543  ILE A CD1 1 
ATOM   3100  N N   . VAL A 1 544 ? 150.515 159.004 124.492 1.00 34.73  ? 544  VAL A N   1 
ATOM   3101  C CA  . VAL A 1 544 ? 151.015 159.368 125.817 1.00 34.73  ? 544  VAL A CA  1 
ATOM   3102  C C   . VAL A 1 544 ? 152.132 160.399 125.705 1.00 34.73  ? 544  VAL A C   1 
ATOM   3103  O O   . VAL A 1 544 ? 152.248 161.309 126.534 1.00 34.73  ? 544  VAL A O   1 
ATOM   3104  C CB  . VAL A 1 544 ? 151.462 158.116 126.585 1.00 34.73  ? 544  VAL A CB  1 
ATOM   3105  C CG1 . VAL A 1 544 ? 151.716 158.454 128.032 1.00 34.73  ? 544  VAL A CG1 1 
ATOM   3106  C CG2 . VAL A 1 544 ? 150.389 157.074 126.510 1.00 34.73  ? 544  VAL A CG2 1 
ATOM   3107  N N   . PHE A 1 545 ? 152.960 160.290 124.671 1.00 40.48  ? 545  PHE A N   1 
ATOM   3108  C CA  . PHE A 1 545 ? 153.885 161.374 124.341 1.00 40.48  ? 545  PHE A CA  1 
ATOM   3109  C C   . PHE A 1 545 ? 153.091 162.396 123.543 1.00 40.48  ? 545  PHE A C   1 
ATOM   3110  O O   . PHE A 1 545 ? 153.145 162.436 122.314 1.00 40.48  ? 545  PHE A O   1 
ATOM   3111  C CB  . PHE A 1 545 ? 155.088 160.864 123.561 1.00 40.48  ? 545  PHE A CB  1 
ATOM   3112  C CG  . PHE A 1 545 ? 156.006 160.003 124.363 1.00 40.48  ? 545  PHE A CG  1 
ATOM   3113  C CD1 . PHE A 1 545 ? 156.034 160.095 125.745 1.00 40.48  ? 545  PHE A CD1 1 
ATOM   3114  C CD2 . PHE A 1 545 ? 156.851 159.109 123.737 1.00 40.48  ? 545  PHE A CD2 1 
ATOM   3115  C CE1 . PHE A 1 545 ? 156.876 159.303 126.486 1.00 40.48  ? 545  PHE A CE1 1 
ATOM   3116  C CE2 . PHE A 1 545 ? 157.699 158.317 124.468 1.00 40.48  ? 545  PHE A CE2 1 
ATOM   3117  C CZ  . PHE A 1 545 ? 157.713 158.413 125.847 1.00 40.48  ? 545  PHE A CZ  1 
ATOM   3118  N N   . SER A 1 546 ? 152.367 163.258 124.269 1.00 34.77  ? 546  SER A N   1 
ATOM   3119  C CA  . SER A 1 546 ? 151.248 163.978 123.662 1.00 34.77  ? 546  SER A CA  1 
ATOM   3120  C C   . SER A 1 546 ? 151.636 165.056 122.650 1.00 34.77  ? 546  SER A C   1 
ATOM   3121  O O   . SER A 1 546 ? 151.171 164.976 121.500 1.00 34.77  ? 546  SER A O   1 
ATOM   3122  C CB  . SER A 1 546 ? 150.309 164.490 124.760 1.00 34.77  ? 546  SER A CB  1 
ATOM   3123  O OG  . SER A 1 546 ? 150.971 165.242 125.755 1.00 34.77  ? 546  SER A OG  1 
ATOM   3124  N N   . PRO A 1 547 ? 152.448 166.084 122.974 1.00 40.98  ? 547  PRO A N   1 
ATOM   3125  C CA  . PRO A 1 547 ? 152.578 167.190 122.013 1.00 40.98  ? 547  PRO A CA  1 
ATOM   3126  C C   . PRO A 1 547 ? 153.446 166.872 120.809 1.00 40.98  ? 547  PRO A C   1 
ATOM   3127  O O   . PRO A 1 547 ? 153.368 167.594 119.809 1.00 40.98  ? 547  PRO A O   1 
ATOM   3128  C CB  . PRO A 1 547 ? 153.193 168.308 122.854 1.00 40.98  ? 547  PRO A CB  1 
ATOM   3129  C CG  . PRO A 1 547 ? 154.071 167.606 123.767 1.00 40.98  ? 547  PRO A CG  1 
ATOM   3130  C CD  . PRO A 1 547 ? 153.435 166.272 124.066 1.00 40.98  ? 547  PRO A CD  1 
ATOM   3131  N N   . LEU A 1 548 ? 154.244 165.814 120.867 1.00 46.32  ? 548  LEU A N   1 
ATOM   3132  C CA  . LEU A 1 548 ? 154.975 165.303 119.718 1.00 46.32  ? 548  LEU A CA  1 
ATOM   3133  C C   . LEU A 1 548 ? 154.056 164.347 118.958 1.00 46.32  ? 548  LEU A C   1 
ATOM   3134  O O   . LEU A 1 548 ? 152.849 164.308 119.220 1.00 46.32  ? 548  LEU A O   1 
ATOM   3135  C CB  . LEU A 1 548 ? 156.262 164.608 120.174 1.00 46.32  ? 548  LEU A CB  1 
ATOM   3136  C CG  . LEU A 1 548 ? 157.195 165.321 121.150 1.00 46.32  ? 548  LEU A CG  1 
ATOM   3137  C CD1 . LEU A 1 548 ? 157.005 164.776 122.554 1.00 46.32  ? 548  LEU A CD1 1 
ATOM   3138  C CD2 . LEU A 1 548 ? 158.635 165.165 120.712 1.00 46.32  ? 548  LEU A CD2 1 
ATOM   3139  N N   . TYR A 1 549 ? 154.626 163.569 118.028 1.00 43.01  ? 549  TYR A N   1 
ATOM   3140  C CA  . TYR A 1 549 ? 153.997 162.390 117.427 1.00 43.01  ? 549  TYR A CA  1 
ATOM   3141  C C   . TYR A 1 549 ? 152.702 162.750 116.692 1.00 43.01  ? 549  TYR A C   1 
ATOM   3142  O O   . TYR A 1 549 ? 151.594 162.514 117.183 1.00 43.01  ? 549  TYR A O   1 
ATOM   3143  C CB  . TYR A 1 549 ? 153.759 161.312 118.488 1.00 43.01  ? 549  TYR A CB  1 
ATOM   3144  C CG  . TYR A 1 549 ? 154.968 160.459 118.751 1.00 43.01  ? 549  TYR A CG  1 
ATOM   3145  C CD1 . TYR A 1 549 ? 155.758 160.002 117.706 1.00 43.01  ? 549  TYR A CD1 1 
ATOM   3146  C CD2 . TYR A 1 549 ? 155.318 160.106 120.043 1.00 43.01  ? 549  TYR A CD2 1 
ATOM   3147  C CE1 . TYR A 1 549 ? 156.861 159.220 117.944 1.00 43.01  ? 549  TYR A CE1 1 
ATOM   3148  C CE2 . TYR A 1 549 ? 156.416 159.324 120.290 1.00 43.01  ? 549  TYR A CE2 1 
ATOM   3149  C CZ  . TYR A 1 549 ? 157.186 158.886 119.241 1.00 43.01  ? 549  TYR A CZ  1 
ATOM   3150  O OH  . TYR A 1 549 ? 158.285 158.104 119.494 1.00 43.01  ? 549  TYR A OH  1 
ATOM   3151  N N   . LYS A 1 550 ? 152.895 163.410 115.541 1.00 36.28  ? 550  LYS A N   1 
ATOM   3152  C CA  . LYS A 1 550 ? 151.857 163.955 114.664 1.00 36.28  ? 550  LYS A CA  1 
ATOM   3153  C C   . LYS A 1 550 ? 150.674 163.027 114.408 1.00 36.28  ? 550  LYS A C   1 
ATOM   3154  O O   . LYS A 1 550 ? 150.832 161.804 114.356 1.00 36.28  ? 550  LYS A O   1 
ATOM   3155  C CB  . LYS A 1 550 ? 152.484 164.331 113.325 1.00 36.28  ? 550  LYS A CB  1 
ATOM   3156  C CG  . LYS A 1 550 ? 153.346 163.234 112.731 1.00 36.28  ? 550  LYS A CG  1 
ATOM   3157  C CD  . LYS A 1 550 ? 153.496 163.413 111.233 1.00 36.28  ? 550  LYS A CD  1 
ATOM   3158  C CE  . LYS A 1 550 ? 154.142 164.749 110.908 1.00 36.28  ? 550  LYS A CE  1 
ATOM   3159  N NZ  . LYS A 1 550 ? 154.400 164.906 109.454 1.00 36.28  ? 550  LYS A NZ  1 
ATOM   3160  N N   . VAL A 1 551 ? 149.488 163.598 114.246 1.00 27.34  ? 551  VAL A N   1 
ATOM   3161  C CA  . VAL A 1 551 ? 148.250 162.836 114.320 1.00 27.34  ? 551  VAL A CA  1 
ATOM   3162  C C   . VAL A 1 551 ? 147.908 162.271 112.949 1.00 27.34  ? 551  VAL A C   1 
ATOM   3163  O O   . VAL A 1 551 ? 147.867 163.005 111.956 1.00 27.34  ? 551  VAL A O   1 
ATOM   3164  C CB  . VAL A 1 551 ? 147.102 163.704 114.848 1.00 27.34  ? 551  VAL A CB  1 
ATOM   3165  C CG1 . VAL A 1 551 ? 145.957 162.833 115.294 1.00 27.34  ? 551  VAL A CG1 1 
ATOM   3166  C CG2 . VAL A 1 551 ? 147.587 164.585 115.977 1.00 27.34  ? 551  VAL A CG2 1 
ATOM   3167  N N   . VAL A 1 552 ? 147.669 160.967 112.897 1.00 21.32  ? 552  VAL A N   1 
ATOM   3168  C CA  . VAL A 1 552 ? 146.982 160.341 111.786 1.00 21.32  ? 552  VAL A CA  1 
ATOM   3169  C C   . VAL A 1 552 ? 145.649 159.825 112.304 1.00 21.32  ? 552  VAL A C   1 
ATOM   3170  O O   . VAL A 1 552 ? 145.301 160.008 113.466 1.00 21.32  ? 552  VAL A O   1 
ATOM   3171  C CB  . VAL A 1 552 ? 147.824 159.225 111.140 1.00 21.32  ? 552  VAL A CB  1 
ATOM   3172  C CG1 . VAL A 1 552 ? 149.098 159.802 110.566 1.00 21.32  ? 552  VAL A CG1 1 
ATOM   3173  C CG2 . VAL A 1 552 ? 148.147 158.165 112.152 1.00 21.32  ? 552  VAL A CG2 1 
ATOM   3174  N N   . MET A 1 553 ? 144.869 159.189 111.428 1.00 19.31  ? 553  MET A N   1 
ATOM   3175  C CA  . MET A 1 553 ? 143.490 158.872 111.781 1.00 19.31  ? 553  MET A CA  1 
ATOM   3176  C C   . MET A 1 553 ? 143.402 157.749 112.804 1.00 19.31  ? 553  MET A C   1 
ATOM   3177  O O   . MET A 1 553 ? 142.464 157.714 113.603 1.00 19.31  ? 553  MET A O   1 
ATOM   3178  C CB  . MET A 1 553 ? 142.703 158.520 110.527 1.00 19.31  ? 553  MET A CB  1 
ATOM   3179  C CG  . MET A 1 553 ? 141.226 158.308 110.745 1.00 19.31  ? 553  MET A CG  1 
ATOM   3180  S SD  . MET A 1 553 ? 140.475 159.681 111.609 1.00 19.31  ? 553  MET A SD  1 
ATOM   3181  C CE  . MET A 1 553 ? 138.790 159.119 111.654 1.00 19.31  ? 553  MET A CE  1 
ATOM   3182  N N   . LEU A 1 554 ? 144.383 156.859 112.845 1.00 24.94  ? 554  LEU A N   1 
ATOM   3183  C CA  . LEU A 1 554 ? 144.421 155.837 113.889 1.00 24.94  ? 554  LEU A CA  1 
ATOM   3184  C C   . LEU A 1 554 ? 145.466 156.228 114.933 1.00 24.94  ? 554  LEU A C   1 
ATOM   3185  O O   . LEU A 1 554 ? 146.202 155.414 115.481 1.00 24.94  ? 554  LEU A O   1 
ATOM   3186  C CB  . LEU A 1 554 ? 144.689 154.463 113.288 1.00 24.94  ? 554  LEU A CB  1 
ATOM   3187  C CG  . LEU A 1 554 ? 144.093 153.319 114.109 1.00 24.94  ? 554  LEU A CG  1 
ATOM   3188  C CD1 . LEU A 1 554 ? 142.587 153.414 114.153 1.00 24.94  ? 554  LEU A CD1 1 
ATOM   3189  C CD2 . LEU A 1 554 ? 144.527 151.992 113.556 1.00 24.94  ? 554  LEU A CD2 1 
ATOM   3190  N N   . ASP A 1 555 ? 145.538 157.531 115.164 1.00 25.66  ? 555  ASP A N   1 
ATOM   3191  C CA  . ASP A 1 555 ? 146.296 158.094 116.268 1.00 25.66  ? 555  ASP A CA  1 
ATOM   3192  C C   . ASP A 1 555 ? 145.363 159.059 116.970 1.00 25.66  ? 555  ASP A C   1 
ATOM   3193  O O   . ASP A 1 555 ? 145.481 159.305 118.170 1.00 25.66  ? 555  ASP A O   1 
ATOM   3194  C CB  . ASP A 1 555 ? 147.558 158.791 115.762 1.00 25.66  ? 555  ASP A CB  1 
ATOM   3195  C CG  . ASP A 1 555 ? 148.539 159.101 116.864 1.00 25.66  ? 555  ASP A CG  1 
ATOM   3196  O OD1 . ASP A 1 555 ? 148.307 158.656 118.002 1.00 25.66  ? 555  ASP A OD1 1 
ATOM   3197  O OD2 . ASP A 1 555 ? 149.544 159.790 116.591 1.00 25.66  ? 555  ASP A OD2 1 
ATOM   3198  N N   . PHE A 1 556 ? 144.425 159.605 116.210 1.00 20.03  ? 556  PHE A N   1 
ATOM   3199  C CA  . PHE A 1 556 ? 143.279 160.303 116.759 1.00 20.03  ? 556  PHE A CA  1 
ATOM   3200  C C   . PHE A 1 556 ? 142.275 159.386 117.397 1.00 20.03  ? 556  PHE A C   1 
ATOM   3201  O O   . PHE A 1 556 ? 141.786 159.713 118.480 1.00 20.03  ? 556  PHE A O   1 
ATOM   3202  C CB  . PHE A 1 556 ? 142.562 161.111 115.666 1.00 20.03  ? 556  PHE A CB  1 
ATOM   3203  C CG  . PHE A 1 556 ? 141.164 161.517 116.030 1.00 20.03  ? 556  PHE A CG  1 
ATOM   3204  C CD1 . PHE A 1 556 ? 140.930 162.480 116.969 1.00 20.03  ? 556  PHE A CD1 1 
ATOM   3205  C CD2 . PHE A 1 556 ? 140.079 160.933 115.407 1.00 20.03  ? 556  PHE A CD2 1 
ATOM   3206  C CE1 . PHE A 1 556 ? 139.638 162.848 117.301 1.00 20.03  ? 556  PHE A CE1 1 
ATOM   3207  C CE2 . PHE A 1 556 ? 138.792 161.292 115.736 1.00 20.03  ? 556  PHE A CE2 1 
ATOM   3208  C CZ  . PHE A 1 556 ? 138.577 162.250 116.679 1.00 20.03  ? 556  PHE A CZ  1 
ATOM   3209  N N   . PHE A 1 557 ? 141.957 158.256 116.778 1.00 20.30  ? 557  PHE A N   1 
ATOM   3210  C CA  . PHE A 1 557 ? 140.805 157.459 117.154 1.00 20.30  ? 557  PHE A CA  1 
ATOM   3211  C C   . PHE A 1 557 ? 140.951 156.800 118.511 1.00 20.30  ? 557  PHE A C   1 
ATOM   3212  O O   . PHE A 1 557 ? 140.061 156.956 119.343 1.00 20.30  ? 557  PHE A O   1 
ATOM   3213  C CB  . PHE A 1 557 ? 140.547 156.393 116.098 1.00 20.30  ? 557  PHE A CB  1 
ATOM   3214  C CG  . PHE A 1 557 ? 139.157 155.858 116.110 1.00 20.30  ? 557  PHE A CG  1 
ATOM   3215  C CD1 . PHE A 1 557 ? 138.894 154.590 116.581 1.00 20.30  ? 557  PHE A CD1 1 
ATOM   3216  C CD2 . PHE A 1 557 ? 138.115 156.620 115.638 1.00 20.30  ? 557  PHE A CD2 1 
ATOM   3217  C CE1 . PHE A 1 557 ? 137.624 154.099 116.581 1.00 20.30  ? 557  PHE A CE1 1 
ATOM   3218  C CE2 . PHE A 1 557 ? 136.843 156.128 115.638 1.00 20.30  ? 557  PHE A CE2 1 
ATOM   3219  C CZ  . PHE A 1 557 ? 136.601 154.868 116.109 1.00 20.30  ? 557  PHE A CZ  1 
ATOM   3220  N N   . MET A 1 558 ? 142.070 156.139 118.792 1.00 21.79  ? 558  MET A N   1 
ATOM   3221  C CA  . MET A 1 558 ? 142.272 155.475 120.072 1.00 21.79  ? 558  MET A CA  1 
ATOM   3222  C C   . MET A 1 558 ? 142.825 156.438 121.118 1.00 21.79  ? 558  MET A C   1 
ATOM   3223  O O   . MET A 1 558 ? 143.286 156.023 122.181 1.00 21.79  ? 558  MET A O   1 
ATOM   3224  C CB  . MET A 1 558 ? 143.185 154.264 119.896 1.00 21.79  ? 558  MET A CB  1 
ATOM   3225  C CG  . MET A 1 558 ? 142.986 153.097 120.872 1.00 21.79  ? 558  MET A CG  1 
ATOM   3226  S SD  . MET A 1 558 ? 141.330 152.396 120.980 1.00 21.79  ? 558  MET A SD  1 
ATOM   3227  C CE  . MET A 1 558 ? 141.271 151.333 119.536 1.00 21.79  ? 558  MET A CE  1 
ATOM   3228  N N   . ALA A 1 559 ? 142.800 157.732 120.820 1.00 27.82  ? 559  ALA A N   1 
ATOM   3229  C CA  . ALA A 1 559 ? 142.994 158.763 121.818 1.00 27.82  ? 559  ALA A CA  1 
ATOM   3230  C C   . ALA A 1 559 ? 141.683 159.337 122.273 1.00 27.82  ? 559  ALA A C   1 
ATOM   3231  O O   . ALA A 1 559 ? 141.617 159.892 123.371 1.00 27.82  ? 559  ALA A O   1 
ATOM   3232  C CB  . ALA A 1 559 ? 143.856 159.910 121.278 1.00 27.82  ? 559  ALA A CB  1 
ATOM   3233  N N   . ASP A 1 560 ? 140.649 159.227 121.458 1.00 35.55  ? 560  ASP A N   1 
ATOM   3234  C CA  . ASP A 1 560 ? 139.329 159.675 121.811 1.00 35.55  ? 560  ASP A CA  1 
ATOM   3235  C C   . ASP A 1 560 ? 138.395 158.496 121.949 1.00 35.55  ? 560  ASP A C   1 
ATOM   3236  O O   . ASP A 1 560 ? 137.200 158.647 121.739 1.00 35.55  ? 560  ASP A O   1 
ATOM   3237  C CB  . ASP A 1 560 ? 138.821 160.663 120.764 1.00 35.55  ? 560  ASP A CB  1 
ATOM   3238  C CG  . ASP A 1 560 ? 137.787 161.601 121.303 1.00 35.55  ? 560  ASP A CG  1 
ATOM   3239  O OD1 . ASP A 1 560 ? 137.412 161.441 122.472 1.00 35.55  ? 560  ASP A OD1 1 
ATOM   3240  O OD2 . ASP A 1 560 ? 137.363 162.517 120.571 1.00 35.55  ? 560  ASP A OD2 1 
ATOM   3241  N N   . GLN A 1 561 ? 138.926 157.305 122.194 1.00 33.67  ? 561  GLN A N   1 
ATOM   3242  C CA  . GLN A 1 561 ? 138.199 156.202 122.803 1.00 33.67  ? 561  GLN A CA  1 
ATOM   3243  C C   . GLN A 1 561 ? 138.468 156.117 124.289 1.00 33.67  ? 561  GLN A C   1 
ATOM   3244  O O   . GLN A 1 561 ? 137.866 155.293 124.973 1.00 33.67  ? 561  GLN A O   1 
ATOM   3245  C CB  . GLN A 1 561 ? 138.592 154.869 122.174 1.00 33.67  ? 561  GLN A CB  1 
ATOM   3246  C CG  . GLN A 1 561 ? 138.296 154.712 120.738 1.00 33.67  ? 561  GLN A CG  1 
ATOM   3247  C CD  . GLN A 1 561 ? 136.864 154.474 120.480 1.00 33.67  ? 561  GLN A CD  1 
ATOM   3248  O OE1 . GLN A 1 561 ? 136.341 153.397 120.730 1.00 33.67  ? 561  GLN A OE1 1 
ATOM   3249  N NE2 . GLN A 1 561 ? 136.203 155.473 119.964 1.00 33.67  ? 561  GLN A NE2 1 
ATOM   3250  N N   . LEU A 1 562 ? 139.391 156.925 124.785 1.00 35.55  ? 562  LEU A N   1 
ATOM   3251  C CA  . LEU A 1 562 ? 139.753 156.970 126.183 1.00 35.55  ? 562  LEU A CA  1 
ATOM   3252  C C   . LEU A 1 562 ? 139.033 158.064 126.935 1.00 35.55  ? 562  LEU A C   1 
ATOM   3253  O O   . LEU A 1 562 ? 139.183 158.158 128.152 1.00 35.55  ? 562  LEU A O   1 
ATOM   3254  C CB  . LEU A 1 562 ? 141.262 157.178 126.331 1.00 35.55  ? 562  LEU A CB  1 
ATOM   3255  C CG  . LEU A 1 562 ? 142.057 155.935 125.978 1.00 35.55  ? 562  LEU A CG  1 
ATOM   3256  C CD1 . LEU A 1 562 ? 143.462 156.296 125.552 1.00 35.55  ? 562  LEU A CD1 1 
ATOM   3257  C CD2 . LEU A 1 562 ? 142.058 155.005 127.172 1.00 35.55  ? 562  LEU A CD2 1 
ATOM   3258  N N   . CYS A 1 563 ? 138.274 158.894 126.254 1.00 20.95  ? 563  CYS A N   1 
ATOM   3259  C CA  . CYS A 1 563 ? 137.376 159.820 126.906 1.00 20.95  ? 563  CYS A CA  1 
ATOM   3260  C C   . CYS A 1 563 ? 136.022 159.193 127.183 1.00 20.95  ? 563  CYS A C   1 
ATOM   3261  O O   . CYS A 1 563 ? 135.048 159.915 127.392 1.00 20.95  ? 563  CYS A O   1 
ATOM   3262  C CB  . CYS A 1 563 ? 137.226 161.069 126.051 1.00 20.95  ? 563  CYS A CB  1 
ATOM   3263  S SG  . CYS A 1 563 ? 138.793 161.654 125.422 1.00 20.95  ? 563  CYS A SG  1 
ATOM   3264  N N   . SER A 1 564 ? 135.936 157.871 127.151 1.00 21.36  ? 564  SER A N   1 
ATOM   3265  C CA  . SER A 1 564 ? 134.836 157.134 127.732 1.00 21.36  ? 564  SER A CA  1 
ATOM   3266  C C   . SER A 1 564 ? 135.306 156.210 128.839 1.00 21.36  ? 564  SER A C   1 
ATOM   3267  O O   . SER A 1 564 ? 134.482 155.617 129.537 1.00 21.36  ? 564  SER A O   1 
ATOM   3268  C CB  . SER A 1 564 ? 134.123 156.337 126.657 1.00 21.36  ? 564  SER A CB  1 
ATOM   3269  O OG  . SER A 1 564 ? 133.729 157.216 125.641 1.00 21.36  ? 564  SER A OG  1 
ATOM   3270  N N   . GLN A 1 565 ? 136.609 156.093 129.026 1.00 19.61  ? 565  GLN A N   1 
ATOM   3271  C CA  . GLN A 1 565 ? 137.213 155.243 130.030 1.00 19.61  ? 565  GLN A CA  1 
ATOM   3272  C C   . GLN A 1 565 ? 137.883 156.090 131.088 1.00 19.61  ? 565  GLN A C   1 
ATOM   3273  O O   . GLN A 1 565 ? 138.996 155.814 131.515 1.00 19.61  ? 565  GLN A O   1 
ATOM   3274  C CB  . GLN A 1 565 ? 138.223 154.288 129.407 1.00 19.61  ? 565  GLN A CB  1 
ATOM   3275  C CG  . GLN A 1 565 ? 137.741 153.498 128.214 1.00 19.61  ? 565  GLN A CG  1 
ATOM   3276  C CD  . GLN A 1 565 ? 136.723 152.477 128.578 1.00 19.61  ? 565  GLN A CD  1 
ATOM   3277  O OE1 . GLN A 1 565 ? 136.640 152.057 129.715 1.00 19.61  ? 565  GLN A OE1 1 
ATOM   3278  N NE2 . GLN A 1 565 ? 135.954 152.049 127.615 1.00 19.61  ? 565  GLN A NE2 1 
ATOM   3279  N N   . VAL A 1 566 ? 137.234 157.171 131.485 1.00 19.24  ? 566  VAL A N   1 
ATOM   3280  C CA  . VAL A 1 566 ? 137.650 157.894 132.680 1.00 19.24  ? 566  VAL A CA  1 
ATOM   3281  C C   . VAL A 1 566 ? 137.299 157.107 133.944 1.00 19.24  ? 566  VAL A C   1 
ATOM   3282  O O   . VAL A 1 566 ? 138.145 157.061 134.844 1.00 19.24  ? 566  VAL A O   1 
ATOM   3283  C CB  . VAL A 1 566 ? 137.070 159.315 132.702 1.00 19.24  ? 566  VAL A CB  1 
ATOM   3284  C CG1 . VAL A 1 566 ? 137.697 160.112 133.791 1.00 19.24  ? 566  VAL A CG1 1 
ATOM   3285  C CG2 . VAL A 1 566 ? 137.316 159.983 131.383 1.00 19.24  ? 566  VAL A CG2 1 
ATOM   3286  N N   . PRO A 1 567 ? 136.124 156.462 134.101 1.00 24.58  ? 567  PRO A N   1 
ATOM   3287  C CA  . PRO A 1 567 ? 135.951 155.617 135.293 1.00 24.58  ? 567  PRO A CA  1 
ATOM   3288  C C   . PRO A 1 567 ? 136.767 154.344 135.281 1.00 24.58  ? 567  PRO A C   1 
ATOM   3289  O O   . PRO A 1 567 ? 137.072 153.826 136.357 1.00 24.58  ? 567  PRO A O   1 
ATOM   3290  C CB  . PRO A 1 567 ? 134.456 155.309 135.285 1.00 24.58  ? 567  PRO A CB  1 
ATOM   3291  C CG  . PRO A 1 567 ? 133.881 156.418 134.566 1.00 24.58  ? 567  PRO A CG  1 
ATOM   3292  C CD  . PRO A 1 567 ? 134.803 156.627 133.457 1.00 24.58  ? 567  PRO A CD  1 
ATOM   3293  N N   . MET A 1 568 ? 137.117 153.811 134.121 1.00 35.55  ? 568  MET A N   1 
ATOM   3294  C CA  . MET A 1 568 ? 138.060 152.709 134.067 1.00 35.55  ? 568  MET A CA  1 
ATOM   3295  C C   . MET A 1 568 ? 139.453 153.111 134.521 1.00 35.55  ? 568  MET A C   1 
ATOM   3296  O O   . MET A 1 568 ? 140.151 152.286 135.104 1.00 35.55  ? 568  MET A O   1 
ATOM   3297  C CB  . MET A 1 568 ? 138.122 152.153 132.650 1.00 35.55  ? 568  MET A CB  1 
ATOM   3298  C CG  . MET A 1 568 ? 138.911 150.898 132.488 1.00 35.55  ? 568  MET A CG  1 
ATOM   3299  S SD  . MET A 1 568 ? 140.584 151.194 131.932 1.00 35.55  ? 568  MET A SD  1 
ATOM   3300  C CE  . MET A 1 568 ? 140.450 150.676 130.244 1.00 35.55  ? 568  MET A CE  1 
ATOM   3301  N N   . LEU A 1 569 ? 139.874 154.355 134.312 1.00 21.61  ? 569  LEU A N   1 
ATOM   3302  C CA  . LEU A 1 569 ? 141.230 154.770 134.643 1.00 21.61  ? 569  LEU A CA  1 
ATOM   3303  C C   . LEU A 1 569 ? 141.355 155.265 136.073 1.00 21.61  ? 569  LEU A C   1 
ATOM   3304  O O   . LEU A 1 569 ? 142.378 155.850 136.433 1.00 21.61  ? 569  LEU A O   1 
ATOM   3305  C CB  . LEU A 1 569 ? 141.711 155.839 133.673 1.00 21.61  ? 569  LEU A CB  1 
ATOM   3306  C CG  . LEU A 1 569 ? 142.307 155.222 132.424 1.00 21.61  ? 569  LEU A CG  1 
ATOM   3307  C CD1 . LEU A 1 569 ? 142.455 156.241 131.323 1.00 21.61  ? 569  LEU A CD1 1 
ATOM   3308  C CD2 . LEU A 1 569 ? 143.637 154.629 132.792 1.00 21.61  ? 569  LEU A CD2 1 
ATOM   3309  N N   . ARG A 1 570 ? 140.324 155.068 136.885 1.00 18.25  ? 570  ARG A N   1 
ATOM   3310  C CA  . ARG A 1 570 ? 140.420 155.177 138.332 1.00 18.25  ? 570  ARG A CA  1 
ATOM   3311  C C   . ARG A 1 570 ? 140.529 153.816 138.989 1.00 18.25  ? 570  ARG A C   1 
ATOM   3312  O O   . ARG A 1 570 ? 141.017 153.705 140.114 1.00 18.25  ? 570  ARG A O   1 
ATOM   3313  C CB  . ARG A 1 570 ? 139.201 155.899 138.893 1.00 18.25  ? 570  ARG A CB  1 
ATOM   3314  C CG  . ARG A 1 570 ? 138.886 157.175 138.192 1.00 18.25  ? 570  ARG A CG  1 
ATOM   3315  C CD  . ARG A 1 570 ? 138.012 158.027 139.047 1.00 18.25  ? 570  ARG A CD  1 
ATOM   3316  N NE  . ARG A 1 570 ? 137.773 159.315 138.425 1.00 18.25  ? 570  ARG A NE  1 
ATOM   3317  C CZ  . ARG A 1 570 ? 136.619 159.666 137.889 1.00 18.25  ? 570  ARG A CZ  1 
ATOM   3318  N NH1 . ARG A 1 570 ? 135.603 158.820 137.900 1.00 18.25  ? 570  ARG A NH1 1 
ATOM   3319  N NH2 . ARG A 1 570 ? 136.484 160.859 137.341 1.00 18.25  ? 570  ARG A NH2 1 
ATOM   3320  N N   . ASN A 1 571 ? 140.058 152.783 138.305 1.00 34.35  ? 571  ASN A N   1 
ATOM   3321  C CA  . ASN A 1 571 ? 140.218 151.403 138.727 1.00 34.35  ? 571  ASN A CA  1 
ATOM   3322  C C   . ASN A 1 571 ? 141.410 150.748 138.069 1.00 34.35  ? 571  ASN A C   1 
ATOM   3323  O O   . ASN A 1 571 ? 141.467 149.531 137.949 1.00 34.35  ? 571  ASN A O   1 
ATOM   3324  C CB  . ASN A 1 571 ? 138.945 150.636 138.424 1.00 34.35  ? 571  ASN A CB  1 
ATOM   3325  C CG  . ASN A 1 571 ? 137.726 151.392 138.823 1.00 34.35  ? 571  ASN A CG  1 
ATOM   3326  O OD1 . ASN A 1 571 ? 137.799 152.309 139.628 1.00 34.35  ? 571  ASN A OD1 1 
ATOM   3327  N ND2 . ASN A 1 571 ? 136.588 151.010 138.282 1.00 34.35  ? 571  ASN A ND2 1 
ATOM   3328  N N   . LEU A 1 572 ? 142.374 151.529 137.613 1.00 35.55  ? 572  LEU A N   1 
ATOM   3329  C CA  . LEU A 1 572 ? 143.661 150.993 137.208 1.00 35.55  ? 572  LEU A CA  1 
ATOM   3330  C C   . LEU A 1 572 ? 144.657 151.922 137.868 1.00 35.55  ? 572  LEU A C   1 
ATOM   3331  O O   . LEU A 1 572 ? 145.862 151.866 137.627 1.00 35.55  ? 572  LEU A O   1 
ATOM   3332  C CB  . LEU A 1 572 ? 143.792 150.925 135.685 1.00 35.55  ? 572  LEU A CB  1 
ATOM   3333  C CG  . LEU A 1 572 ? 144.892 150.140 134.961 1.00 35.55  ? 572  LEU A CG  1 
ATOM   3334  C CD1 . LEU A 1 572 ? 144.335 149.553 133.705 1.00 35.55  ? 572  LEU A CD1 1 
ATOM   3335  C CD2 . LEU A 1 572 ? 146.051 151.006 134.557 1.00 35.55  ? 572  LEU A CD2 1 
ATOM   3336  N N   . GLU A 1 573 ? 144.144 152.777 138.728 1.00 32.72  ? 573  GLU A N   1 
ATOM   3337  C CA  . GLU A 1 573 ? 144.983 153.530 139.643 1.00 32.72  ? 573  GLU A CA  1 
ATOM   3338  C C   . GLU A 1 573 ? 144.690 153.217 141.098 1.00 32.72  ? 573  GLU A C   1 
ATOM   3339  O O   . GLU A 1 573 ? 145.505 153.539 141.963 1.00 32.72  ? 573  GLU A O   1 
ATOM   3340  C CB  . GLU A 1 573 ? 144.849 155.035 139.400 1.00 32.72  ? 573  GLU A CB  1 
ATOM   3341  C CG  . GLU A 1 573 ? 145.951 155.607 138.523 1.00 32.72  ? 573  GLU A CG  1 
ATOM   3342  C CD  . GLU A 1 573 ? 147.345 155.221 138.992 1.00 32.72  ? 573  GLU A CD  1 
ATOM   3343  O OE1 . GLU A 1 573 ? 147.962 154.336 138.365 1.00 32.72  ? 573  GLU A OE1 1 
ATOM   3344  O OE2 . GLU A 1 573 ? 147.830 155.806 139.981 1.00 32.72  ? 573  GLU A OE2 1 
ATOM   3345  N N   . TYR A 1 574 ? 143.548 152.610 141.412 1.00 36.24  ? 574  TYR A N   1 
ATOM   3346  C CA  . TYR A 1 574 ? 143.404 152.107 142.768 1.00 36.24  ? 574  TYR A CA  1 
ATOM   3347  C C   . TYR A 1 574 ? 144.152 150.797 142.917 1.00 36.24  ? 574  TYR A C   1 
ATOM   3348  O O   . TYR A 1 574 ? 144.738 150.535 143.971 1.00 36.24  ? 574  TYR A O   1 
ATOM   3349  C CB  . TYR A 1 574 ? 141.955 151.917 143.182 1.00 36.24  ? 574  TYR A CB  1 
ATOM   3350  C CG  . TYR A 1 574 ? 141.904 151.542 144.634 1.00 36.24  ? 574  TYR A CG  1 
ATOM   3351  C CD1 . TYR A 1 574 ? 142.410 152.402 145.597 1.00 36.24  ? 574  TYR A CD1 1 
ATOM   3352  C CD2 . TYR A 1 574 ? 141.413 150.313 145.044 1.00 36.24  ? 574  TYR A CD2 1 
ATOM   3353  C CE1 . TYR A 1 574 ? 142.394 152.066 146.933 1.00 36.24  ? 574  TYR A CE1 1 
ATOM   3354  C CE2 . TYR A 1 574 ? 141.392 149.966 146.383 1.00 36.24  ? 574  TYR A CE2 1 
ATOM   3355  C CZ  . TYR A 1 574 ? 141.888 150.847 147.320 1.00 36.24  ? 574  TYR A CZ  1 
ATOM   3356  O OH  . TYR A 1 574 ? 141.868 150.514 148.653 1.00 36.24  ? 574  TYR A OH  1 
ATOM   3357  N N   . ILE A 1 575 ? 144.124 149.973 141.871 1.00 25.11  ? 575  ILE A N   1 
ATOM   3358  C CA  . ILE A 1 575 ? 144.815 148.693 141.855 1.00 25.11  ? 575  ILE A CA  1 
ATOM   3359  C C   . ILE A 1 575 ? 146.313 148.899 141.996 1.00 25.11  ? 575  ILE A C   1 
ATOM   3360  O O   . ILE A 1 575 ? 146.938 148.313 142.883 1.00 25.11  ? 575  ILE A O   1 
ATOM   3361  C CB  . ILE A 1 575 ? 144.494 147.892 140.588 1.00 25.11  ? 575  ILE A CB  1 
ATOM   3362  C CG1 . ILE A 1 575 ? 143.065 147.385 140.628 1.00 25.11  ? 575  ILE A CG1 1 
ATOM   3363  C CG2 . ILE A 1 575 ? 145.440 146.741 140.434 1.00 25.11  ? 575  ILE A CG2 1 
ATOM   3364  C CD1 . ILE A 1 575 ? 142.703 146.679 139.371 1.00 25.11  ? 575  ILE A CD1 1 
ATOM   3365  N N   . ALA A 1 576 ? 146.899 149.787 141.198 1.00 29.24  ? 576  ALA A N   1 
ATOM   3366  C CA  . ALA A 1 576 ? 148.330 150.022 141.350 1.00 29.24  ? 576  ALA A CA  1 
ATOM   3367  C C   . ALA A 1 576 ? 148.600 151.087 142.407 1.00 29.24  ? 576  ALA A C   1 
ATOM   3368  O O   . ALA A 1 576 ? 149.372 152.023 142.186 1.00 29.24  ? 576  ALA A O   1 
ATOM   3369  C CB  . ALA A 1 576 ? 148.958 150.427 140.019 1.00 29.24  ? 576  ALA A CB  1 
ATOM   3370  N N   . CYS A 1 577 ? 147.957 150.931 143.562 1.00 40.92  ? 577  CYS A N   1 
ATOM   3371  C CA  . CYS A 1 577 ? 148.249 151.597 144.820 1.00 40.92  ? 577  CYS A CA  1 
ATOM   3372  C C   . CYS A 1 577 ? 148.126 150.510 145.877 1.00 40.92  ? 577  CYS A C   1 
ATOM   3373  O O   . CYS A 1 577 ? 148.669 150.604 146.979 1.00 40.92  ? 577  CYS A O   1 
ATOM   3374  C CB  . CYS A 1 577 ? 147.278 152.752 145.067 1.00 40.92  ? 577  CYS A CB  1 
ATOM   3375  S SG  . CYS A 1 577 ? 147.419 153.564 146.673 1.00 40.92  ? 577  CYS A SG  1 
ATOM   3376  N N   . TYR A 1 578 ? 147.395 149.462 145.515 1.00 47.19  ? 578  TYR A N   1 
ATOM   3377  C CA  . TYR A 1 578 ? 147.132 148.315 146.365 1.00 47.19  ? 578  TYR A CA  1 
ATOM   3378  C C   . TYR A 1 578 ? 148.052 147.175 145.930 1.00 47.19  ? 578  TYR A C   1 
ATOM   3379  O O   . TYR A 1 578 ? 147.896 146.030 146.360 1.00 47.19  ? 578  TYR A O   1 
ATOM   3380  C CB  . TYR A 1 578 ? 145.642 147.967 146.249 1.00 47.19  ? 578  TYR A CB  1 
ATOM   3381  C CG  . TYR A 1 578 ? 145.111 146.965 147.233 1.00 47.19  ? 578  TYR A CG  1 
ATOM   3382  C CD1 . TYR A 1 578 ? 144.910 147.312 148.557 1.00 47.19  ? 578  TYR A CD1 1 
ATOM   3383  C CD2 . TYR A 1 578 ? 144.779 145.679 146.830 1.00 47.19  ? 578  TYR A CD2 1 
ATOM   3384  C CE1 . TYR A 1 578 ? 144.420 146.400 149.464 1.00 47.19  ? 578  TYR A CE1 1 
ATOM   3385  C CE2 . TYR A 1 578 ? 144.289 144.756 147.732 1.00 47.19  ? 578  TYR A CE2 1 
ATOM   3386  C CZ  . TYR A 1 578 ? 144.114 145.123 149.052 1.00 47.19  ? 578  TYR A CZ  1 
ATOM   3387  O OH  . TYR A 1 578 ? 143.623 144.208 149.958 1.00 47.19  ? 578  TYR A OH  1 
ATOM   3388  N N   . TYR A 1 579 ? 149.009 147.478 145.055 1.00 43.31  ? 579  TYR A N   1 
ATOM   3389  C CA  . TYR A 1 579 ? 149.933 146.473 144.542 1.00 43.31  ? 579  TYR A CA  1 
ATOM   3390  C C   . TYR A 1 579 ? 151.334 147.054 144.371 1.00 43.31  ? 579  TYR A C   1 
ATOM   3391  O O   . TYR A 1 579 ? 152.227 146.391 143.836 1.00 43.31  ? 579  TYR A O   1 
ATOM   3392  C CB  . TYR A 1 579 ? 149.394 145.913 143.220 1.00 43.31  ? 579  TYR A CB  1 
ATOM   3393  C CG  . TYR A 1 579 ? 150.069 144.665 142.694 1.00 43.31  ? 579  TYR A CG  1 
ATOM   3394  C CD1 . TYR A 1 579 ? 150.589 144.628 141.404 1.00 43.31  ? 579  TYR A CD1 1 
ATOM   3395  C CD2 . TYR A 1 579 ? 150.198 143.536 143.485 1.00 43.31  ? 579  TYR A CD2 1 
ATOM   3396  C CE1 . TYR A 1 579 ? 151.209 143.492 140.913 1.00 43.31  ? 579  TYR A CE1 1 
ATOM   3397  C CE2 . TYR A 1 579 ? 150.820 142.394 143.005 1.00 43.31  ? 579  TYR A CE2 1 
ATOM   3398  C CZ  . TYR A 1 579 ? 151.322 142.379 141.721 1.00 43.31  ? 579  TYR A CZ  1 
ATOM   3399  O OH  . TYR A 1 579 ? 151.939 141.244 141.250 1.00 43.31  ? 579  TYR A OH  1 
ATOM   3400  N N   . ILE A 1 580 ? 151.557 148.290 144.813 1.00 40.83  ? 580  ILE A N   1 
ATOM   3401  C CA  . ILE A 1 580 ? 152.846 148.921 144.546 1.00 40.83  ? 580  ILE A CA  1 
ATOM   3402  C C   . ILE A 1 580 ? 153.439 149.534 145.809 1.00 40.83  ? 580  ILE A C   1 
ATOM   3403  O O   . ILE A 1 580 ? 154.627 149.874 145.842 1.00 40.83  ? 580  ILE A O   1 
ATOM   3404  C CB  . ILE A 1 580 ? 152.727 149.964 143.415 1.00 40.83  ? 580  ILE A CB  1 
ATOM   3405  C CG1 . ILE A 1 580 ? 154.044 150.084 142.643 1.00 40.83  ? 580  ILE A CG1 1 
ATOM   3406  C CG2 . ILE A 1 580 ? 152.300 151.326 143.947 1.00 40.83  ? 580  ILE A CG2 1 
ATOM   3407  C CD1 . ILE A 1 580 ? 154.401 148.858 141.840 1.00 40.83  ? 580  ILE A CD1 1 
ATOM   3408  N N   . THR A 1 581 ? 152.644 149.663 146.865 1.00 42.88  ? 581  THR A N   1 
ATOM   3409  C CA  . THR A 1 581 ? 153.159 150.229 148.108 1.00 42.88  ? 581  THR A CA  1 
ATOM   3410  C C   . THR A 1 581 ? 152.856 149.302 149.280 1.00 42.88  ? 581  THR A C   1 
ATOM   3411  O O   . THR A 1 581 ? 153.083 149.627 150.449 1.00 42.88  ? 581  THR A O   1 
ATOM   3412  C CB  . THR A 1 581 ? 152.618 151.644 148.325 1.00 42.88  ? 581  THR A CB  1 
ATOM   3413  O OG1 . THR A 1 581 ? 153.433 152.328 149.284 1.00 42.88  ? 581  THR A OG1 1 
ATOM   3414  C CG2 . THR A 1 581 ? 151.174 151.634 148.799 1.00 42.88  ? 581  THR A CG2 1 
ATOM   3415  N N   . GLY A 1 582 ? 152.405 148.091 148.967 1.00 52.32  ? 582  GLY A N   1 
ATOM   3416  C CA  . GLY A 1 582 ? 152.179 147.095 149.993 1.00 52.32  ? 582  GLY A CA  1 
ATOM   3417  C C   . GLY A 1 582 ? 150.976 147.375 150.866 1.00 52.32  ? 582  GLY A C   1 
ATOM   3418  O O   . GLY A 1 582 ? 151.118 147.723 152.041 1.00 52.32  ? 582  GLY A O   1 
ATOM   3419  N N   . SER A 1 583 ? 149.782 147.248 150.292 1.00 55.54  ? 583  SER A N   1 
ATOM   3420  C CA  . SER A 1 583 ? 148.546 147.429 151.036 1.00 55.54  ? 583  SER A CA  1 
ATOM   3421  C C   . SER A 1 583 ? 147.731 146.145 151.095 1.00 55.54  ? 583  SER A C   1 
ATOM   3422  O O   . SER A 1 583 ? 146.641 146.143 151.674 1.00 55.54  ? 583  SER A O   1 
ATOM   3423  C CB  . SER A 1 583 ? 147.709 148.548 150.415 1.00 55.54  ? 583  SER A CB  1 
ATOM   3424  O OG  . SER A 1 583 ? 148.367 149.792 150.540 1.00 55.54  ? 583  SER A OG  1 
ATOM   3425  N N   . TYR A 1 584 ? 148.240 145.058 150.522 1.00 53.67  ? 584  TYR A N   1 
ATOM   3426  C CA  . TYR A 1 584 ? 147.509 143.802 150.417 1.00 53.67  ? 584  TYR A CA  1 
ATOM   3427  C C   . TYR A 1 584 ? 147.912 142.839 151.525 1.00 53.67  ? 584  TYR A C   1 
ATOM   3428  O O   . TYR A 1 584 ? 147.054 142.219 152.161 1.00 53.67  ? 584  TYR A O   1 
ATOM   3429  C CB  . TYR A 1 584 ? 147.717 143.162 149.033 1.00 53.67  ? 584  TYR A CB  1 
ATOM   3430  C CG  . TYR A 1 584 ? 149.148 142.849 148.599 1.00 53.67  ? 584  TYR A CG  1 
ATOM   3431  C CD1 . TYR A 1 584 ? 150.034 143.854 148.221 1.00 53.67  ? 584  TYR A CD1 1 
ATOM   3432  C CD2 . TYR A 1 584 ? 149.590 141.537 148.519 1.00 53.67  ? 584  TYR A CD2 1 
ATOM   3433  C CE1 . TYR A 1 584 ? 151.318 143.563 147.814 1.00 53.67  ? 584  TYR A CE1 1 
ATOM   3434  C CE2 . TYR A 1 584 ? 150.876 141.238 148.107 1.00 53.67  ? 584  TYR A CE2 1 
ATOM   3435  C CZ  . TYR A 1 584 ? 151.731 142.256 147.756 1.00 53.67  ? 584  TYR A CZ  1 
ATOM   3436  O OH  . TYR A 1 584 ? 153.009 141.968 147.347 1.00 53.67  ? 584  TYR A OH  1 
ATOM   3437  N N   . ALA A 1 585 ? 149.213 142.709 151.769 1.00 55.32  ? 585  ALA A N   1 
ATOM   3438  C CA  . ALA A 1 585 ? 149.697 141.834 152.827 1.00 55.32  ? 585  ALA A CA  1 
ATOM   3439  C C   . ALA A 1 585 ? 149.531 142.500 154.185 1.00 55.32  ? 585  ALA A C   1 
ATOM   3440  O O   . ALA A 1 585 ? 149.514 141.824 155.217 1.00 55.32  ? 585  ALA A O   1 
ATOM   3441  C CB  . ALA A 1 585 ? 151.160 141.461 152.589 1.00 55.32  ? 585  ALA A CB  1 
ATOM   3442  N N   . THR A 1 586 ? 149.418 143.827 154.192 1.00 55.60  ? 586  THR A N   1 
ATOM   3443  C CA  . THR A 1 586 ? 149.334 144.577 155.438 1.00 55.60  ? 586  THR A CA  1 
ATOM   3444  C C   . THR A 1 586 ? 147.889 144.809 155.867 1.00 55.60  ? 586  THR A C   1 
ATOM   3445  O O   . THR A 1 586 ? 147.646 145.433 156.907 1.00 55.60  ? 586  THR A O   1 
ATOM   3446  C CB  . THR A 1 586 ? 150.070 145.907 155.296 1.00 55.60  ? 586  THR A CB  1 
ATOM   3447  O OG1 . THR A 1 586 ? 149.320 146.784 154.447 1.00 55.60  ? 586  THR A OG1 1 
ATOM   3448  C CG2 . THR A 1 586 ? 151.441 145.674 154.690 1.00 55.60  ? 586  THR A CG2 1 
ATOM   3449  N N   . GLN A 1 587 ? 146.940 144.319 155.058 1.00 57.52  ? 587  GLN A N   1 
ATOM   3450  C CA  . GLN A 1 587 ? 145.509 144.273 155.359 1.00 57.52  ? 587  GLN A CA  1 
ATOM   3451  C C   . GLN A 1 587 ? 144.887 145.631 155.658 1.00 57.52  ? 587  GLN A C   1 
ATOM   3452  O O   . GLN A 1 587 ? 144.454 145.879 156.788 1.00 57.52  ? 587  GLN A O   1 
ATOM   3453  C CB  . GLN A 1 587 ? 145.235 143.337 156.541 1.00 57.52  ? 587  GLN A CB  1 
ATOM   3454  C CG  . GLN A 1 587 ? 145.243 141.832 156.268 1.00 57.52  ? 587  GLN A CG  1 
ATOM   3455  C CD  . GLN A 1 587 ? 144.010 141.301 155.538 1.00 57.52  ? 587  GLN A CD  1 
ATOM   3456  O OE1 . GLN A 1 587 ? 143.510 141.892 154.585 1.00 57.52  ? 587  GLN A OE1 1 
ATOM   3457  N NE2 . GLN A 1 587 ? 143.486 140.193 156.035 1.00 57.52  ? 587  GLN A NE2 1 
ATOM   3458  N N   . ASP A 1 588 ? 144.832 146.514 154.664 1.00 60.79  ? 588  ASP A N   1 
ATOM   3459  C CA  . ASP A 1 588 ? 144.214 147.820 154.852 1.00 60.79  ? 588  ASP A CA  1 
ATOM   3460  C C   . ASP A 1 588 ? 143.625 148.363 153.554 1.00 60.79  ? 588  ASP A C   1 
ATOM   3461  O O   . ASP A 1 588 ? 144.355 148.660 152.604 1.00 60.79  ? 588  ASP A O   1 
ATOM   3462  C CB  . ASP A 1 588 ? 145.230 148.796 155.454 1.00 60.79  ? 588  ASP A CB  1 
ATOM   3463  C CG  . ASP A 1 588 ? 145.556 148.486 156.907 1.00 60.79  ? 588  ASP A CG  1 
ATOM   3464  O OD1 . ASP A 1 588 ? 144.816 147.715 157.546 1.00 60.79  ? 588  ASP A OD1 1 
ATOM   3465  O OD2 . ASP A 1 588 ? 146.561 149.027 157.416 1.00 60.79  ? 588  ASP A OD2 1 
ATOM   3466  N N   . TYR A 1 589 ? 142.295 148.497 153.505 1.00 55.85  ? 589  TYR A N   1 
ATOM   3467  C CA  . TYR A 1 589 ? 141.597 148.989 152.322 1.00 55.85  ? 589  TYR A CA  1 
ATOM   3468  C C   . TYR A 1 589 ? 141.511 150.509 152.280 1.00 55.85  ? 589  TYR A C   1 
ATOM   3469  O O   . TYR A 1 589 ? 140.921 151.071 151.349 1.00 55.85  ? 589  TYR A O   1 
ATOM   3470  C CB  . TYR A 1 589 ? 140.199 148.371 152.236 1.00 55.85  ? 589  TYR A CB  1 
ATOM   3471  C CG  . TYR A 1 589 ? 139.447 148.304 153.549 1.00 55.85  ? 589  TYR A CG  1 
ATOM   3472  C CD1 . TYR A 1 589 ? 139.300 147.104 154.225 1.00 55.85  ? 589  TYR A CD1 1 
ATOM   3473  C CD2 . TYR A 1 589 ? 138.849 149.433 154.088 1.00 55.85  ? 589  TYR A CD2 1 
ATOM   3474  C CE1 . TYR A 1 589 ? 138.608 147.034 155.418 1.00 55.85  ? 589  TYR A CE1 1 
ATOM   3475  C CE2 . TYR A 1 589 ? 138.154 149.376 155.281 1.00 55.85  ? 589  TYR A CE2 1 
ATOM   3476  C CZ  . TYR A 1 589 ? 138.036 148.173 155.940 1.00 55.85  ? 589  TYR A CZ  1 
ATOM   3477  O OH  . TYR A 1 589 ? 137.342 148.113 157.124 1.00 55.85  ? 589  TYR A OH  1 
ATOM   3478  N N   . GLU A 1 590 ? 142.088 151.191 153.266 1.00 57.78  ? 590  GLU A N   1 
ATOM   3479  C CA  . GLU A 1 590 ? 142.079 152.648 153.253 1.00 57.78  ? 590  GLU A CA  1 
ATOM   3480  C C   . GLU A 1 590 ? 143.477 153.244 153.183 1.00 57.78  ? 590  GLU A C   1 
ATOM   3481  O O   . GLU A 1 590 ? 143.622 154.432 153.485 1.00 57.78  ? 590  GLU A O   1 
ATOM   3482  C CB  . GLU A 1 590 ? 141.370 153.201 154.496 1.00 57.78  ? 590  GLU A CB  1 
ATOM   3483  C CG  . GLU A 1 590 ? 139.910 152.809 154.634 1.00 57.78  ? 590  GLU A CG  1 
ATOM   3484  C CD  . GLU A 1 590 ? 138.988 153.650 153.777 1.00 57.78  ? 590  GLU A CD  1 
ATOM   3485  O OE1 . GLU A 1 590 ? 139.025 154.891 153.905 1.00 57.78  ? 590  GLU A OE1 1 
ATOM   3486  O OE2 . GLU A 1 590 ? 138.218 153.069 152.985 1.00 57.78  ? 590  GLU A OE2 1 
ATOM   3487  N N   . TYR A 1 591 ? 144.505 152.477 152.806 1.00 60.60  ? 591  TYR A N   1 
ATOM   3488  C CA  . TYR A 1 591 ? 145.873 152.988 152.836 1.00 60.60  ? 591  TYR A CA  1 
ATOM   3489  C C   . TYR A 1 591 ? 146.097 154.043 151.762 1.00 60.60  ? 591  TYR A C   1 
ATOM   3490  O O   . TYR A 1 591 ? 146.911 154.957 151.932 1.00 60.60  ? 591  TYR A O   1 
ATOM   3491  C CB  . TYR A 1 591 ? 146.868 151.840 152.674 1.00 60.60  ? 591  TYR A CB  1 
ATOM   3492  C CG  . TYR A 1 591 ? 148.306 152.238 152.924 1.00 60.60  ? 591  TYR A CG  1 
ATOM   3493  C CD1 . TYR A 1 591 ? 149.149 152.587 151.873 1.00 60.60  ? 591  TYR A CD1 1 
ATOM   3494  C CD2 . TYR A 1 591 ? 148.820 152.270 154.215 1.00 60.60  ? 591  TYR A CD2 1 
ATOM   3495  C CE1 . TYR A 1 591 ? 150.461 152.952 152.102 1.00 60.60  ? 591  TYR A CE1 1 
ATOM   3496  C CE2 . TYR A 1 591 ? 150.132 152.633 154.452 1.00 60.60  ? 591  TYR A CE2 1 
ATOM   3497  C CZ  . TYR A 1 591 ? 150.947 152.973 153.392 1.00 60.60  ? 591  TYR A CZ  1 
ATOM   3498  O OH  . TYR A 1 591 ? 152.253 153.335 153.622 1.00 60.60  ? 591  TYR A OH  1 
ATOM   3499  N N   . CYS A 1 592 ? 145.390 153.928 150.643 1.00 55.86  ? 592  CYS A N   1 
ATOM   3500  C CA  . CYS A 1 592 ? 145.497 154.928 149.591 1.00 55.86  ? 592  CYS A CA  1 
ATOM   3501  C C   . CYS A 1 592 ? 144.739 156.195 149.965 1.00 55.86  ? 592  CYS A C   1 
ATOM   3502  O O   . CYS A 1 592 ? 145.277 157.300 149.852 1.00 55.86  ? 592  CYS A O   1 
ATOM   3503  C CB  . CYS A 1 592 ? 144.983 154.366 148.266 1.00 55.86  ? 592  CYS A CB  1 
ATOM   3504  S SG  . CYS A 1 592 ? 145.827 152.868 147.723 1.00 55.86  ? 592  CYS A SG  1 
ATOM   3505  N N   . MET A 1 593 ? 143.494 156.048 150.418 1.00 51.10  ? 593  MET A N   1 
ATOM   3506  C CA  . MET A 1 593 ? 142.627 157.199 150.637 1.00 51.10  ? 593  MET A CA  1 
ATOM   3507  C C   . MET A 1 593 ? 142.727 157.791 152.045 1.00 51.10  ? 593  MET A C   1 
ATOM   3508  O O   . MET A 1 593 ? 141.712 158.031 152.708 1.00 51.10  ? 593  MET A O   1 
ATOM   3509  C CB  . MET A 1 593 ? 141.186 156.815 150.273 1.00 51.10  ? 593  MET A CB  1 
ATOM   3510  C CG  . MET A 1 593 ? 140.637 155.571 150.954 1.00 51.10  ? 593  MET A CG  1 
ATOM   3511  S SD  . MET A 1 593 ? 138.969 155.182 150.388 1.00 51.10  ? 593  MET A SD  1 
ATOM   3512  C CE  . MET A 1 593 ? 138.018 156.504 151.135 1.00 51.10  ? 593  MET A CE  1 
ATOM   3513  N N   . ARG A 1 594 ? 143.951 158.074 152.492 1.00 57.31  ? 594  ARG A N   1 
ATOM   3514  C CA  . ARG A 1 594 ? 144.168 158.860 153.702 1.00 57.31  ? 594  ARG A CA  1 
ATOM   3515  C C   . ARG A 1 594 ? 144.850 160.175 153.358 1.00 57.31  ? 594  ARG A C   1 
ATOM   3516  O O   . ARG A 1 594 ? 144.384 161.252 153.740 1.00 57.31  ? 594  ARG A O   1 
ATOM   3517  C CB  . ARG A 1 594 ? 145.024 158.100 154.719 1.00 57.31  ? 594  ARG A CB  1 
ATOM   3518  C CG  . ARG A 1 594 ? 144.344 156.923 155.369 1.00 57.31  ? 594  ARG A CG  1 
ATOM   3519  C CD  . ARG A 1 594 ? 145.316 156.123 156.218 1.00 57.31  ? 594  ARG A CD  1 
ATOM   3520  N NE  . ARG A 1 594 ? 144.884 154.736 156.368 1.00 57.31  ? 594  ARG A NE  1 
ATOM   3521  C CZ  . ARG A 1 594 ? 144.065 154.301 157.319 1.00 57.31  ? 594  ARG A CZ  1 
ATOM   3522  N NH1 . ARG A 1 594 ? 143.579 155.145 158.218 1.00 57.31  ? 594  ARG A NH1 1 
ATOM   3523  N NH2 . ARG A 1 594 ? 143.732 153.020 157.371 1.00 57.31  ? 594  ARG A NH2 1 
ATOM   3524  N N   . VAL A 1 595 ? 145.958 160.083 152.630 1.00 53.70  ? 595  VAL A N   1 
ATOM   3525  C CA  . VAL A 1 595 ? 146.794 161.228 152.293 1.00 53.70  ? 595  VAL A CA  1 
ATOM   3526  C C   . VAL A 1 595 ? 146.190 161.994 151.125 1.00 53.70  ? 595  VAL A C   1 
ATOM   3527  O O   . VAL A 1 595 ? 145.200 161.561 150.527 1.00 53.70  ? 595  VAL A O   1 
ATOM   3528  C CB  . VAL A 1 595 ? 148.233 160.780 151.981 1.00 53.70  ? 595  VAL A CB  1 
ATOM   3529  C CG1 . VAL A 1 595 ? 148.985 160.492 153.267 1.00 53.70  ? 595  VAL A CG1 1 
ATOM   3530  C CG2 . VAL A 1 595 ? 148.211 159.540 151.109 1.00 53.70  ? 595  VAL A CG2 1 
ATOM   3531  N N   . LYS A 1 596 ? 146.778 163.151 150.809 1.00 52.29  ? 596  LYS A N   1 
ATOM   3532  C CA  . LYS A 1 596 ? 146.358 164.027 149.716 1.00 52.29  ? 596  LYS A CA  1 
ATOM   3533  C C   . LYS A 1 596 ? 146.456 163.380 148.337 1.00 52.29  ? 596  LYS A C   1 
ATOM   3534  O O   . LYS A 1 596 ? 145.866 163.878 147.372 1.00 52.29  ? 596  LYS A O   1 
ATOM   3535  C CB  . LYS A 1 596 ? 147.208 165.298 149.729 1.00 52.29  ? 596  LYS A CB  1 
ATOM   3536  C CG  . LYS A 1 596 ? 148.701 165.026 149.580 1.00 52.29  ? 596  LYS A CG  1 
ATOM   3537  C CD  . LYS A 1 596 ? 149.547 166.217 149.992 1.00 52.29  ? 596  LYS A CD  1 
ATOM   3538  C CE  . LYS A 1 596 ? 149.901 167.091 148.799 1.00 52.29  ? 596  LYS A CE  1 
ATOM   3539  N NZ  . LYS A 1 596 ? 150.365 168.443 149.218 1.00 52.29  ? 596  LYS A NZ  1 
ATOM   3540  N N   . TYR A 1 597 ? 147.238 162.303 148.240 1.00 48.76  ? 597  TYR A N   1 
ATOM   3541  C CA  . TYR A 1 597 ? 147.401 161.452 147.068 1.00 48.76  ? 597  TYR A CA  1 
ATOM   3542  C C   . TYR A 1 597 ? 146.064 160.991 146.495 1.00 48.76  ? 597  TYR A C   1 
ATOM   3543  O O   . TYR A 1 597 ? 145.888 160.978 145.275 1.00 48.76  ? 597  TYR A O   1 
ATOM   3544  C CB  . TYR A 1 597 ? 148.308 160.277 147.456 1.00 48.76  ? 597  TYR A CB  1 
ATOM   3545  C CG  . TYR A 1 597 ? 148.614 159.248 146.395 1.00 48.76  ? 597  TYR A CG  1 
ATOM   3546  C CD1 . TYR A 1 597 ? 149.331 159.585 145.255 1.00 48.76  ? 597  TYR A CD1 1 
ATOM   3547  C CD2 . TYR A 1 597 ? 148.285 157.913 146.592 1.00 48.76  ? 597  TYR A CD2 1 
ATOM   3548  C CE1 . TYR A 1 597 ? 149.639 158.632 144.300 1.00 48.76  ? 597  TYR A CE1 1 
ATOM   3549  C CE2 . TYR A 1 597 ? 148.594 156.952 145.646 1.00 48.76  ? 597  TYR A CE2 1 
ATOM   3550  C CZ  . TYR A 1 597 ? 149.269 157.319 144.501 1.00 48.76  ? 597  TYR A CZ  1 
ATOM   3551  O OH  . TYR A 1 597 ? 149.583 156.370 143.553 1.00 48.76  ? 597  TYR A OH  1 
ATOM   3552  N N   . TYR A 1 598 ? 145.117 160.609 147.350 1.00 46.38  ? 598  TYR A N   1 
ATOM   3553  C CA  . TYR A 1 598 ? 143.805 160.225 146.845 1.00 46.38  ? 598  TYR A CA  1 
ATOM   3554  C C   . TYR A 1 598 ? 142.738 161.263 147.133 1.00 46.38  ? 598  TYR A C   1 
ATOM   3555  O O   . TYR A 1 598 ? 141.581 160.921 147.391 1.00 46.38  ? 598  TYR A O   1 
ATOM   3556  C CB  . TYR A 1 598 ? 143.376 158.879 147.403 1.00 46.38  ? 598  TYR A CB  1 
ATOM   3557  C CG  . TYR A 1 598 ? 143.657 157.801 146.413 1.00 46.38  ? 598  TYR A CG  1 
ATOM   3558  C CD1 . TYR A 1 598 ? 142.667 156.928 145.990 1.00 46.38  ? 598  TYR A CD1 1 
ATOM   3559  C CD2 . TYR A 1 598 ? 144.918 157.689 145.860 1.00 46.38  ? 598  TYR A CD2 1 
ATOM   3560  C CE1 . TYR A 1 598 ? 142.949 155.954 145.060 1.00 46.38  ? 598  TYR A CE1 1 
ATOM   3561  C CE2 . TYR A 1 598 ? 145.206 156.734 144.944 1.00 46.38  ? 598  TYR A CE2 1 
ATOM   3562  C CZ  . TYR A 1 598 ? 144.231 155.877 144.547 1.00 46.38  ? 598  TYR A CZ  1 
ATOM   3563  O OH  . TYR A 1 598 ? 144.587 154.948 143.624 1.00 46.38  ? 598  TYR A OH  1 
ATOM   3564  N N   . ARG A 1 599 ? 143.120 162.532 147.105 1.00 47.79  ? 599  ARG A N   1 
ATOM   3565  C CA  . ARG A 1 599 ? 142.159 163.619 147.080 1.00 47.79  ? 599  ARG A CA  1 
ATOM   3566  C C   . ARG A 1 599 ? 142.222 164.392 145.770 1.00 47.79  ? 599  ARG A C   1 
ATOM   3567  O O   . ARG A 1 599 ? 141.184 164.835 145.267 1.00 47.79  ? 599  ARG A O   1 
ATOM   3568  C CB  . ARG A 1 599 ? 142.384 164.545 148.276 1.00 47.79  ? 599  ARG A CB  1 
ATOM   3569  C CG  . ARG A 1 599 ? 142.157 163.852 149.609 1.00 47.79  ? 599  ARG A CG  1 
ATOM   3570  C CD  . ARG A 1 599 ? 142.316 164.802 150.780 1.00 47.79  ? 599  ARG A CD  1 
ATOM   3571  N NE  . ARG A 1 599 ? 141.240 165.788 150.826 1.00 47.79  ? 599  ARG A NE  1 
ATOM   3572  C CZ  . ARG A 1 599 ? 141.197 166.812 151.672 1.00 47.79  ? 599  ARG A CZ  1 
ATOM   3573  N NH1 . ARG A 1 599 ? 142.174 166.990 152.552 1.00 47.79  ? 599  ARG A NH1 1 
ATOM   3574  N NH2 . ARG A 1 599 ? 140.176 167.657 151.642 1.00 47.79  ? 599  ARG A NH2 1 
ATOM   3575  N N   . ASP A 1 600 ? 143.414 164.553 145.201 1.00 41.09  ? 600  ASP A N   1 
ATOM   3576  C CA  . ASP A 1 600 ? 143.566 165.209 143.912 1.00 41.09  ? 600  ASP A CA  1 
ATOM   3577  C C   . ASP A 1 600 ? 144.212 164.273 142.901 1.00 41.09  ? 600  ASP A C   1 
ATOM   3578  O O   . ASP A 1 600 ? 143.683 164.082 141.806 1.00 41.09  ? 600  ASP A O   1 
ATOM   3579  C CB  . ASP A 1 600 ? 144.396 166.487 144.059 1.00 41.09  ? 600  ASP A CB  1 
ATOM   3580  C CG  . ASP A 1 600 ? 143.966 167.583 143.096 1.00 41.09  ? 600  ASP A CG  1 
ATOM   3581  O OD1 . ASP A 1 600 ? 144.747 168.540 142.895 1.00 41.09  ? 600  ASP A OD1 1 
ATOM   3582  O OD2 . ASP A 1 600 ? 142.850 167.492 142.539 1.00 41.09  ? 600  ASP A OD2 1 
ATOM   3583  N N   . LEU A 1 601 ? 145.323 163.641 143.272 1.00 31.09  ? 601  LEU A N   1 
ATOM   3584  C CA  . LEU A 1 601 ? 146.162 162.954 142.294 1.00 31.09  ? 601  LEU A CA  1 
ATOM   3585  C C   . LEU A 1 601 ? 145.642 161.572 141.915 1.00 31.09  ? 601  LEU A C   1 
ATOM   3586  O O   . LEU A 1 601 ? 146.301 160.846 141.169 1.00 31.09  ? 601  LEU A O   1 
ATOM   3587  C CB  . LEU A 1 601 ? 147.603 162.843 142.798 1.00 31.09  ? 601  LEU A CB  1 
ATOM   3588  C CG  . LEU A 1 601 ? 148.538 164.042 142.587 1.00 31.09  ? 601  LEU A CG  1 
ATOM   3589  C CD1 . LEU A 1 601 ? 148.269 165.188 143.555 1.00 31.09  ? 601  LEU A CD1 1 
ATOM   3590  C CD2 . LEU A 1 601 ? 149.993 163.606 142.662 1.00 31.09  ? 601  LEU A CD2 1 
ATOM   3591  N N   . ALA A 1 602 ? 144.499 161.182 142.441 1.00 32.27  ? 602  ALA A N   1 
ATOM   3592  C CA  . ALA A 1 602 ? 143.752 160.082 141.849 1.00 32.27  ? 602  ALA A CA  1 
ATOM   3593  C C   . ALA A 1 602 ? 142.497 160.577 141.164 1.00 32.27  ? 602  ALA A C   1 
ATOM   3594  O O   . ALA A 1 602 ? 141.638 159.763 140.820 1.00 32.27  ? 602  ALA A O   1 
ATOM   3595  C CB  . ALA A 1 602 ? 143.385 159.039 142.900 1.00 32.27  ? 602  ALA A CB  1 
ATOM   3596  N N   . TYR A 1 603 ? 142.353 161.882 140.990 1.00 30.63  ? 603  TYR A N   1 
ATOM   3597  C CA  . TYR A 1 603 ? 141.245 162.487 140.285 1.00 30.63  ? 603  TYR A CA  1 
ATOM   3598  C C   . TYR A 1 603 ? 141.736 163.531 139.294 1.00 30.63  ? 603  TYR A C   1 
ATOM   3599  O O   . TYR A 1 603 ? 141.028 163.834 138.330 1.00 30.63  ? 603  TYR A O   1 
ATOM   3600  C CB  . TYR A 1 603 ? 140.275 163.116 141.291 1.00 30.63  ? 603  TYR A CB  1 
ATOM   3601  C CG  . TYR A 1 603 ? 139.030 163.692 140.690 1.00 30.63  ? 603  TYR A CG  1 
ATOM   3602  C CD1 . TYR A 1 603 ? 138.708 165.025 140.873 1.00 30.63  ? 603  TYR A CD1 1 
ATOM   3603  C CD2 . TYR A 1 603 ? 138.174 162.905 139.945 1.00 30.63  ? 603  TYR A CD2 1 
ATOM   3604  C CE1 . TYR A 1 603 ? 137.573 165.554 140.335 1.00 30.63  ? 603  TYR A CE1 1 
ATOM   3605  C CE2 . TYR A 1 603 ? 137.036 163.425 139.405 1.00 30.63  ? 603  TYR A CE2 1 
ATOM   3606  C CZ  . TYR A 1 603 ? 136.743 164.750 139.602 1.00 30.63  ? 603  TYR A CZ  1 
ATOM   3607  O OH  . TYR A 1 603 ? 135.607 165.283 139.061 1.00 30.63  ? 603  TYR A OH  1 
ATOM   3608  N N   . ALA A 1 604 ? 142.940 164.065 139.489 1.00 32.76  ? 604  ALA A N   1 
ATOM   3609  C CA  . ALA A 1 604 ? 143.515 165.023 138.559 1.00 32.76  ? 604  ALA A CA  1 
ATOM   3610  C C   . ALA A 1 604 ? 144.286 164.312 137.462 1.00 32.76  ? 604  ALA A C   1 
ATOM   3611  O O   . ALA A 1 604 ? 144.371 164.815 136.341 1.00 32.76  ? 604  ALA A O   1 
ATOM   3612  C CB  . ALA A 1 604 ? 144.433 166.011 139.277 1.00 32.76  ? 604  ALA A CB  1 
ATOM   3613  N N   . VAL A 1 605 ? 144.862 163.152 137.761 1.00 25.40  ? 605  VAL A N   1 
ATOM   3614  C CA  . VAL A 1 605 ? 145.520 162.384 136.712 1.00 25.40  ? 605  VAL A CA  1 
ATOM   3615  C C   . VAL A 1 605 ? 144.466 161.452 136.136 1.00 25.40  ? 605  VAL A C   1 
ATOM   3616  O O   . VAL A 1 605 ? 144.712 160.728 135.167 1.00 25.40  ? 605  VAL A O   1 
ATOM   3617  C CB  . VAL A 1 605 ? 146.753 161.619 137.228 1.00 25.40  ? 605  VAL A CB  1 
ATOM   3618  C CG1 . VAL A 1 605 ? 146.347 160.353 137.956 1.00 25.40  ? 605  VAL A CG1 1 
ATOM   3619  C CG2 . VAL A 1 605 ? 147.745 161.342 136.103 1.00 25.40  ? 605  VAL A CG2 1 
ATOM   3620  N N   . SER A 1 606 ? 143.277 161.457 136.729 1.00 21.29  ? 606  SER A N   1 
ATOM   3621  C CA  . SER A 1 606 ? 142.156 160.805 136.082 1.00 21.29  ? 606  SER A CA  1 
ATOM   3622  C C   . SER A 1 606 ? 141.723 161.541 134.825 1.00 21.29  ? 606  SER A C   1 
ATOM   3623  O O   . SER A 1 606 ? 141.244 160.893 133.891 1.00 21.29  ? 606  SER A O   1 
ATOM   3624  C CB  . SER A 1 606 ? 140.987 160.683 137.044 1.00 21.29  ? 606  SER A CB  1 
ATOM   3625  O OG  . SER A 1 606 ? 139.793 160.423 136.346 1.00 21.29  ? 606  SER A OG  1 
ATOM   3626  N N   . PHE A 1 607 ? 141.885 162.866 134.770 1.00 26.13  ? 607  PHE A N   1 
ATOM   3627  C CA  . PHE A 1 607 ? 141.710 163.623 133.523 1.00 26.13  ? 607  PHE A CA  1 
ATOM   3628  C C   . PHE A 1 607 ? 143.022 163.812 132.798 1.00 26.13  ? 607  PHE A C   1 
ATOM   3629  O O   . PHE A 1 607 ? 143.386 164.903 132.378 1.00 26.13  ? 607  PHE A O   1 
ATOM   3630  C CB  . PHE A 1 607 ? 141.077 164.969 133.804 1.00 26.13  ? 607  PHE A CB  1 
ATOM   3631  C CG  . PHE A 1 607 ? 139.679 164.864 134.197 1.00 26.13  ? 607  PHE A CG  1 
ATOM   3632  C CD1 . PHE A 1 607 ? 138.704 164.647 133.251 1.00 26.13  ? 607  PHE A CD1 1 
ATOM   3633  C CD2 . PHE A 1 607 ? 139.336 164.929 135.523 1.00 26.13  ? 607  PHE A CD2 1 
ATOM   3634  C CE1 . PHE A 1 607 ? 137.409 164.529 133.623 1.00 26.13  ? 607  PHE A CE1 1 
ATOM   3635  C CE2 . PHE A 1 607 ? 138.051 164.807 135.902 1.00 26.13  ? 607  PHE A CE2 1 
ATOM   3636  C CZ  . PHE A 1 607 ? 137.085 164.616 134.954 1.00 26.13  ? 607  PHE A CZ  1 
ATOM   3637  N N   . LEU A 1 608 ? 143.742 162.748 132.691 1.00 22.72  ? 608  LEU A N   1 
ATOM   3638  C CA  . LEU A 1 608 ? 144.815 162.616 131.735 1.00 22.72  ? 608  LEU A CA  1 
ATOM   3639  C C   . LEU A 1 608 ? 144.355 162.288 130.307 1.00 22.72  ? 608  LEU A C   1 
ATOM   3640  O O   . LEU A 1 608 ? 145.054 162.720 129.383 1.00 22.72  ? 608  LEU A O   1 
ATOM   3641  C CB  . LEU A 1 608 ? 145.816 161.591 132.253 1.00 22.72  ? 608  LEU A CB  1 
ATOM   3642  C CG  . LEU A 1 608 ? 147.212 161.644 131.647 1.00 22.72  ? 608  LEU A CG  1 
ATOM   3643  C CD1 . LEU A 1 608 ? 147.799 163.032 131.804 1.00 22.72  ? 608  LEU A CD1 1 
ATOM   3644  C CD2 . LEU A 1 608 ? 148.086 160.630 132.345 1.00 22.72  ? 608  LEU A CD2 1 
ATOM   3645  N N   . PRO A 1 609 ? 143.271 161.528 130.030 1.00 28.57  ? 609  PRO A N   1 
ATOM   3646  C CA  . PRO A 1 609 ? 142.899 161.336 128.614 1.00 28.57  ? 609  PRO A CA  1 
ATOM   3647  C C   . PRO A 1 609 ? 142.429 162.591 127.900 1.00 28.57  ? 609  PRO A C   1 
ATOM   3648  O O   . PRO A 1 609 ? 142.576 162.670 126.674 1.00 28.57  ? 609  PRO A O   1 
ATOM   3649  C CB  . PRO A 1 609 ? 141.779 160.296 128.684 1.00 28.57  ? 609  PRO A CB  1 
ATOM   3650  C CG  . PRO A 1 609 ? 142.019 159.594 129.888 1.00 28.57  ? 609  PRO A CG  1 
ATOM   3651  C CD  . PRO A 1 609 ? 142.469 160.593 130.848 1.00 28.57  ? 609  PRO A CD  1 
ATOM   3652  N N   . TYR A 1 610 ? 141.877 163.569 128.613 1.00 35.55  ? 610  TYR A N   1 
ATOM   3653  C CA  . TYR A 1 610 ? 141.509 164.846 128.026 1.00 35.55  ? 610  TYR A CA  1 
ATOM   3654  C C   . TYR A 1 610 ? 142.684 165.789 127.926 1.00 35.55  ? 610  TYR A C   1 
ATOM   3655  O O   . TYR A 1 610 ? 142.539 166.869 127.366 1.00 35.55  ? 610  TYR A O   1 
ATOM   3656  C CB  . TYR A 1 610 ? 140.410 165.525 128.831 1.00 35.55  ? 610  TYR A CB  1 
ATOM   3657  C CG  . TYR A 1 610 ? 139.044 164.917 128.717 1.00 35.55  ? 610  TYR A CG  1 
ATOM   3658  C CD1 . TYR A 1 610 ? 138.737 163.732 129.345 1.00 35.55  ? 610  TYR A CD1 1 
ATOM   3659  C CD2 . TYR A 1 610 ? 138.050 165.554 128.025 1.00 35.55  ? 610  TYR A CD2 1 
ATOM   3660  C CE1 . TYR A 1 610 ? 137.495 163.185 129.261 1.00 35.55  ? 610  TYR A CE1 1 
ATOM   3661  C CE2 . TYR A 1 610 ? 136.798 165.013 127.939 1.00 35.55  ? 610  TYR A CE2 1 
ATOM   3662  C CZ  . TYR A 1 610 ? 136.529 163.829 128.562 1.00 35.55  ? 610  TYR A CZ  1 
ATOM   3663  O OH  . TYR A 1 610 ? 135.278 163.275 128.480 1.00 35.55  ? 610  TYR A OH  1 
ATOM   3664  N N   . TYR A 1 611 ? 143.828 165.432 128.477 1.00 30.73  ? 611  TYR A N   1 
ATOM   3665  C CA  . TYR A 1 611 ? 145.052 166.155 128.189 1.00 30.73  ? 611  TYR A CA  1 
ATOM   3666  C C   . TYR A 1 611 ? 145.739 165.654 126.942 1.00 30.73  ? 611  TYR A C   1 
ATOM   3667  O O   . TYR A 1 611 ? 146.365 166.448 126.242 1.00 30.73  ? 611  TYR A O   1 
ATOM   3668  C CB  . TYR A 1 611 ? 146.039 166.070 129.363 1.00 30.73  ? 611  TYR A CB  1 
ATOM   3669  C CG  . TYR A 1 611 ? 147.431 166.601 129.062 1.00 30.73  ? 611  TYR A CG  1 
ATOM   3670  C CD1 . TYR A 1 611 ? 148.489 165.741 128.788 1.00 30.73  ? 611  TYR A CD1 1 
ATOM   3671  C CD2 . TYR A 1 611 ? 147.685 167.961 129.046 1.00 30.73  ? 611  TYR A CD2 1 
ATOM   3672  C CE1 . TYR A 1 611 ? 149.748 166.223 128.507 1.00 30.73  ? 611  TYR A CE1 1 
ATOM   3673  C CE2 . TYR A 1 611 ? 148.948 168.446 128.774 1.00 30.73  ? 611  TYR A CE2 1 
ATOM   3674  C CZ  . TYR A 1 611 ? 149.968 167.570 128.501 1.00 30.73  ? 611  TYR A CZ  1 
ATOM   3675  O OH  . TYR A 1 611 ? 151.223 168.047 128.228 1.00 30.73  ? 611  TYR A OH  1 
ATOM   3676  N N   . TRP A 1 612 ? 145.650 164.362 126.647 1.00 20.80  ? 612  TRP A N   1 
ATOM   3677  C CA  . TRP A 1 612 ? 146.297 163.845 125.452 1.00 20.80  ? 612  TRP A CA  1 
ATOM   3678  C C   . TRP A 1 612 ? 145.601 164.312 124.183 1.00 20.80  ? 612  TRP A C   1 
ATOM   3679  O O   . TRP A 1 612 ? 146.257 164.502 123.155 1.00 20.80  ? 612  TRP A O   1 
ATOM   3680  C CB  . TRP A 1 612 ? 146.336 162.324 125.491 1.00 20.80  ? 612  TRP A CB  1 
ATOM   3681  C CG  . TRP A 1 612 ? 147.006 161.743 126.689 1.00 20.80  ? 612  TRP A CG  1 
ATOM   3682  C CD1 . TRP A 1 612 ? 147.991 162.306 127.434 1.00 20.80  ? 612  TRP A CD1 1 
ATOM   3683  C CD2 . TRP A 1 612 ? 146.753 160.458 127.260 1.00 20.80  ? 612  TRP A CD2 1 
ATOM   3684  N NE1 . TRP A 1 612 ? 148.360 161.453 128.443 1.00 20.80  ? 612  TRP A NE1 1 
ATOM   3685  C CE2 . TRP A 1 612 ? 147.610 160.311 128.355 1.00 20.80  ? 612  TRP A CE2 1 
ATOM   3686  C CE3 . TRP A 1 612 ? 145.875 159.418 126.950 1.00 20.80  ? 612  TRP A CE3 1 
ATOM   3687  C CZ2 . TRP A 1 612 ? 147.622 159.166 129.134 1.00 20.80  ? 612  TRP A CZ2 1 
ATOM   3688  C CZ3 . TRP A 1 612 ? 145.886 158.291 127.728 1.00 20.80  ? 612  TRP A CZ3 1 
ATOM   3689  C CH2 . TRP A 1 612 ? 146.748 158.175 128.811 1.00 20.80  ? 612  TRP A CH2 1 
ATOM   3690  N N   . ARG A 1 613 ? 144.288 164.512 124.242 1.00 20.94  ? 613  ARG A N   1 
ATOM   3691  C CA  . ARG A 1 613 ? 143.541 165.033 123.110 1.00 20.94  ? 613  ARG A CA  1 
ATOM   3692  C C   . ARG A 1 613 ? 143.916 166.481 122.852 1.00 20.94  ? 613  ARG A C   1 
ATOM   3693  O O   . ARG A 1 613 ? 144.236 166.858 121.723 1.00 20.94  ? 613  ARG A O   1 
ATOM   3694  C CB  . ARG A 1 613 ? 142.041 164.920 123.359 1.00 20.94  ? 613  ARG A CB  1 
ATOM   3695  C CG  . ARG A 1 613 ? 141.441 163.590 123.012 1.00 20.94  ? 613  ARG A CG  1 
ATOM   3696  C CD  . ARG A 1 613 ? 141.879 163.108 121.643 1.00 20.94  ? 613  ARG A CD  1 
ATOM   3697  N NE  . ARG A 1 613 ? 141.428 163.981 120.571 1.00 20.94  ? 613  ARG A NE  1 
ATOM   3698  C CZ  . ARG A 1 613 ? 142.206 164.384 119.580 1.00 20.94  ? 613  ARG A CZ  1 
ATOM   3699  N NH1 . ARG A 1 613 ? 143.457 163.983 119.531 1.00 20.94  ? 613  ARG A NH1 1 
ATOM   3700  N NH2 . ARG A 1 613 ? 141.735 165.182 118.641 1.00 20.94  ? 613  ARG A NH2 1 
ATOM   3701  N N   . ALA A 1 614 ? 143.900 167.294 123.902 1.00 21.45  ? 614  ALA A N   1 
ATOM   3702  C CA  . ALA A 1 614 ? 144.149 168.721 123.779 1.00 21.45  ? 614  ALA A CA  1 
ATOM   3703  C C   . ALA A 1 614 ? 145.593 169.038 123.420 1.00 21.45  ? 614  ALA A C   1 
ATOM   3704  O O   . ALA A 1 614 ? 145.897 170.171 123.052 1.00 21.45  ? 614  ALA A O   1 
ATOM   3705  C CB  . ALA A 1 614 ? 143.765 169.438 125.070 1.00 21.45  ? 614  ALA A CB  1 
ATOM   3706  N N   . MET A 1 615 ? 146.498 168.076 123.533 1.00 31.45  ? 615  MET A N   1 
ATOM   3707  C CA  . MET A 1 615 ? 147.849 168.298 123.046 1.00 31.45  ? 615  MET A CA  1 
ATOM   3708  C C   . MET A 1 615 ? 148.152 167.544 121.765 1.00 31.45  ? 615  MET A C   1 
ATOM   3709  O O   . MET A 1 615 ? 149.311 167.516 121.348 1.00 31.45  ? 615  MET A O   1 
ATOM   3710  C CB  . MET A 1 615 ? 148.864 167.939 124.120 1.00 31.45  ? 615  MET A CB  1 
ATOM   3711  C CG  . MET A 1 615 ? 148.875 168.938 125.246 1.00 31.45  ? 615  MET A CG  1 
ATOM   3712  S SD  . MET A 1 615 ? 150.112 170.230 125.022 1.00 31.45  ? 615  MET A SD  1 
ATOM   3713  C CE  . MET A 1 615 ? 149.434 171.538 126.040 1.00 31.45  ? 615  MET A CE  1 
ATOM   3714  N N   . GLN A 1 616 ? 147.149 166.931 121.139 1.00 26.64  ? 616  GLN A N   1 
ATOM   3715  C CA  . GLN A 1 616 ? 147.286 166.460 119.767 1.00 26.64  ? 616  GLN A CA  1 
ATOM   3716  C C   . GLN A 1 616 ? 146.725 167.459 118.773 1.00 26.64  ? 616  GLN A C   1 
ATOM   3717  O O   . GLN A 1 616 ? 147.206 167.523 117.638 1.00 26.64  ? 616  GLN A O   1 
ATOM   3718  C CB  . GLN A 1 616 ? 146.569 165.127 119.580 1.00 26.64  ? 616  GLN A CB  1 
ATOM   3719  C CG  . GLN A 1 616 ? 147.332 163.906 120.022 1.00 26.64  ? 616  GLN A CG  1 
ATOM   3720  C CD  . GLN A 1 616 ? 146.436 162.704 120.107 1.00 26.64  ? 616  GLN A CD  1 
ATOM   3721  O OE1 . GLN A 1 616 ? 145.462 162.603 119.377 1.00 26.64  ? 616  GLN A OE1 1 
ATOM   3722  N NE2 . GLN A 1 616 ? 146.750 161.789 121.006 1.00 26.64  ? 616  GLN A NE2 1 
ATOM   3723  N N   . CYS A 1 617 ? 145.709 168.221 119.175 1.00 27.26  ? 617  CYS A N   1 
ATOM   3724  C CA  . CYS A 1 617 ? 145.208 169.352 118.412 1.00 27.26  ? 617  CYS A CA  1 
ATOM   3725  C C   . CYS A 1 617 ? 146.184 170.513 118.400 1.00 27.26  ? 617  CYS A C   1 
ATOM   3726  O O   . CYS A 1 617 ? 146.151 171.323 117.473 1.00 27.26  ? 617  CYS A O   1 
ATOM   3727  C CB  . CYS A 1 617 ? 143.870 169.815 118.979 1.00 27.26  ? 617  CYS A CB  1 
ATOM   3728  S SG  . CYS A 1 617 ? 142.715 168.480 119.255 1.00 27.26  ? 617  CYS A SG  1 
ATOM   3729  N N   . ALA A 1 618 ? 147.047 170.613 119.408 1.00 32.91  ? 618  ALA A N   1 
ATOM   3730  C CA  . ALA A 1 618 ? 148.091 171.625 119.394 1.00 32.91  ? 618  ALA A CA  1 
ATOM   3731  C C   . ALA A 1 618 ? 149.153 171.292 118.359 1.00 32.91  ? 618  ALA A C   1 
ATOM   3732  O O   . ALA A 1 618 ? 149.622 172.181 117.644 1.00 32.91  ? 618  ALA A O   1 
ATOM   3733  C CB  . ALA A 1 618 ? 148.717 171.764 120.779 1.00 32.91  ? 618  ALA A CB  1 
ATOM   3734  N N   . ARG A 1 619 ? 149.547 170.026 118.260 1.00 41.55  ? 619  ARG A N   1 
ATOM   3735  C CA  . ARG A 1 619 ? 150.386 169.724 117.107 1.00 41.55  ? 619  ARG A CA  1 
ATOM   3736  C C   . ARG A 1 619 ? 149.579 169.722 115.801 1.00 41.55  ? 619  ARG A C   1 
ATOM   3737  O O   . ARG A 1 619 ? 150.088 170.021 114.710 1.00 41.55  ? 619  ARG A O   1 
ATOM   3738  C CB  . ARG A 1 619 ? 151.125 168.395 117.296 1.00 41.55  ? 619  ARG A CB  1 
ATOM   3739  C CG  . ARG A 1 619 ? 152.153 168.120 116.203 1.00 41.55  ? 619  ARG A CG  1 
ATOM   3740  C CD  . ARG A 1 619 ? 153.234 167.148 116.584 1.00 41.55  ? 619  ARG A CD  1 
ATOM   3741  N NE  . ARG A 1 619 ? 153.874 166.621 115.386 1.00 41.55  ? 619  ARG A NE  1 
ATOM   3742  C CZ  . ARG A 1 619 ? 155.068 166.041 115.359 1.00 41.55  ? 619  ARG A CZ  1 
ATOM   3743  N NH1 . ARG A 1 619 ? 155.778 165.927 116.470 1.00 41.55  ? 619  ARG A NH1 1 
ATOM   3744  N NH2 . ARG A 1 619 ? 155.558 165.589 114.214 1.00 41.55  ? 619  ARG A NH2 1 
ATOM   3745  N N   . ARG A 1 620 ? 148.269 169.494 115.831 1.00 36.08  ? 620  ARG A N   1 
ATOM   3746  C CA  . ARG A 1 620 ? 147.439 169.672 114.647 1.00 36.08  ? 620  ARG A CA  1 
ATOM   3747  C C   . ARG A 1 620 ? 147.081 171.135 114.399 1.00 36.08  ? 620  ARG A C   1 
ATOM   3748  O O   . ARG A 1 620 ? 146.262 171.417 113.522 1.00 36.08  ? 620  ARG A O   1 
ATOM   3749  C CB  . ARG A 1 620 ? 146.171 168.821 114.743 1.00 36.08  ? 620  ARG A CB  1 
ATOM   3750  C CG  . ARG A 1 620 ? 145.899 168.001 113.495 1.00 36.08  ? 620  ARG A CG  1 
ATOM   3751  C CD  . ARG A 1 620 ? 144.878 166.917 113.743 1.00 36.08  ? 620  ARG A CD  1 
ATOM   3752  N NE  . ARG A 1 620 ? 143.557 167.455 114.047 1.00 36.08  ? 620  ARG A NE  1 
ATOM   3753  C CZ  . ARG A 1 620 ? 142.475 166.707 114.234 1.00 36.08  ? 620  ARG A CZ  1 
ATOM   3754  N NH1 . ARG A 1 620 ? 142.553 165.390 114.151 1.00 36.08  ? 620  ARG A NH1 1 
ATOM   3755  N NH2 . ARG A 1 620 ? 141.312 167.274 114.506 1.00 36.08  ? 620  ARG A NH2 1 
ATOM   3756  N N   . TRP A 1 621 ? 147.699 172.072 115.122 1.00 45.38  ? 621  TRP A N   1 
ATOM   3757  C CA  . TRP A 1 621 ? 147.557 173.500 114.867 1.00 45.38  ? 621  TRP A CA  1 
ATOM   3758  C C   . TRP A 1 621 ? 148.854 174.150 114.413 1.00 45.38  ? 621  TRP A C   1 
ATOM   3759  O O   . TRP A 1 621 ? 148.839 174.908 113.438 1.00 45.38  ? 621  TRP A O   1 
ATOM   3760  C CB  . TRP A 1 621 ? 147.022 174.219 116.109 1.00 45.38  ? 621  TRP A CB  1 
ATOM   3761  C CG  . TRP A 1 621 ? 147.363 175.665 116.151 1.00 45.38  ? 621  TRP A CG  1 
ATOM   3762  C CD1 . TRP A 1 621 ? 146.849 176.652 115.364 1.00 45.38  ? 621  TRP A CD1 1 
ATOM   3763  C CD2 . TRP A 1 621 ? 148.287 176.299 117.038 1.00 45.38  ? 621  TRP A CD2 1 
ATOM   3764  N NE1 . TRP A 1 621 ? 147.400 177.863 115.704 1.00 45.38  ? 621  TRP A NE1 1 
ATOM   3765  C CE2 . TRP A 1 621 ? 148.287 177.672 116.729 1.00 45.38  ? 621  TRP A CE2 1 
ATOM   3766  C CE3 . TRP A 1 621 ? 149.120 175.837 118.062 1.00 45.38  ? 621  TRP A CE3 1 
ATOM   3767  C CZ2 . TRP A 1 621 ? 149.086 178.587 117.406 1.00 45.38  ? 621  TRP A CZ2 1 
ATOM   3768  C CZ3 . TRP A 1 621 ? 149.911 176.744 118.733 1.00 45.38  ? 621  TRP A CZ3 1 
ATOM   3769  C CH2 . TRP A 1 621 ? 149.889 178.104 118.403 1.00 45.38  ? 621  TRP A CH2 1 
ATOM   3770  N N   . PHE A 1 622 ? 149.892 173.930 115.213 1.00 44.17  ? 622  PHE A N   1 
ATOM   3771  C CA  . PHE A 1 622 ? 151.232 174.405 114.822 1.00 44.17  ? 622  PHE A CA  1 
ATOM   3772  C C   . PHE A 1 622 ? 151.635 173.470 113.702 1.00 44.17  ? 622  PHE A C   1 
ATOM   3773  O O   . PHE A 1 622 ? 152.819 173.399 113.367 1.00 44.17  ? 622  PHE A O   1 
ATOM   3774  C CB  . PHE A 1 622 ? 152.164 174.490 116.036 1.00 44.17  ? 622  PHE A CB  1 
ATOM   3775  C CG  . PHE A 1 622 ? 153.609 174.890 115.857 1.00 44.17  ? 622  PHE A CG  1 
ATOM   3776  C CD1 . PHE A 1 622 ? 153.942 176.227 115.719 1.00 44.17  ? 622  PHE A CD1 1 
ATOM   3777  C CD2 . PHE A 1 622 ? 154.619 173.951 115.729 1.00 44.17  ? 622  PHE A CD2 1 
ATOM   3778  C CE1 . PHE A 1 622 ? 155.254 176.618 115.509 1.00 44.17  ? 622  PHE A CE1 1 
ATOM   3779  C CE2 . PHE A 1 622 ? 155.932 174.342 115.522 1.00 44.17  ? 622  PHE A CE2 1 
ATOM   3780  C CZ  . PHE A 1 622 ? 156.248 175.675 115.412 1.00 44.17  ? 622  PHE A CZ  1 
ATOM   3781  N N   . ASP A 1 623 ? 150.651 172.748 113.181 1.00 56.17  ? 623  ASP A N   1 
ATOM   3782  C CA  . ASP A 1 623 ? 150.903 171.896 111.990 1.00 56.17  ? 623  ASP A CA  1 
ATOM   3783  C C   . ASP A 1 623 ? 149.582 171.826 111.227 1.00 56.17  ? 623  ASP A C   1 
ATOM   3784  O O   . ASP A 1 623 ? 148.570 171.487 111.873 1.00 56.17  ? 623  ASP A O   1 
ATOM   3785  C CB  . ASP A 1 623 ? 151.510 170.543 112.351 1.00 56.17  ? 623  ASP A CB  1 
ATOM   3786  C CG  . ASP A 1 623 ? 151.235 169.469 111.315 1.00 56.17  ? 623  ASP A CG  1 
ATOM   3787  O OD1 . ASP A 1 623 ? 150.937 168.327 111.721 1.00 56.17  ? 623  ASP A OD1 1 
ATOM   3788  O OD2 . ASP A 1 623 ? 151.327 169.782 110.110 1.00 56.17  ? 623  ASP A OD2 1 
ATOM   3789  N N   . GLU A 1 624 ? 149.607 172.130 109.927 1.00 58.17  ? 624  GLU A N   1 
ATOM   3790  C CA  . GLU A 1 624 ? 148.378 172.226 109.125 1.00 58.17  ? 624  GLU A CA  1 
ATOM   3791  C C   . GLU A 1 624 ? 147.637 173.551 109.344 1.00 58.17  ? 624  GLU A C   1 
ATOM   3792  O O   . GLU A 1 624 ? 146.749 173.909 108.564 1.00 58.17  ? 624  GLU A O   1 
ATOM   3793  C CB  . GLU A 1 624 ? 147.460 171.014 109.389 1.00 58.17  ? 624  GLU A CB  1 
ATOM   3794  C CG  . GLU A 1 624 ? 146.360 170.737 108.386 1.00 58.17  ? 624  GLU A CG  1 
ATOM   3795  C CD  . GLU A 1 624 ? 145.383 169.707 108.898 1.00 58.17  ? 624  GLU A CD  1 
ATOM   3796  O OE1 . GLU A 1 624 ? 144.183 170.026 109.001 1.00 58.17  ? 624  GLU A OE1 1 
ATOM   3797  O OE2 . GLU A 1 624 ? 145.817 168.578 109.208 1.00 58.17  ? 624  GLU A OE2 1 
ATOM   3798  N N   . GLY A 1 625 ? 148.020 174.316 110.362 1.00 55.22  ? 625  GLY A N   1 
ATOM   3799  C CA  . GLY A 1 625 ? 147.716 175.731 110.423 1.00 55.22  ? 625  GLY A CA  1 
ATOM   3800  C C   . GLY A 1 625 ? 146.320 176.187 110.801 1.00 55.22  ? 625  GLY A C   1 
ATOM   3801  O O   . GLY A 1 625 ? 146.176 177.258 111.396 1.00 55.22  ? 625  GLY A O   1 
ATOM   3802  N N   . GLU A 1 626 ? 145.292 175.400 110.480 1.00 54.93  ? 626  GLU A N   1 
ATOM   3803  C CA  . GLU A 1 626 ? 143.942 175.946 110.362 1.00 54.93  ? 626  GLU A CA  1 
ATOM   3804  C C   . GLU A 1 626 ? 143.313 176.256 111.716 1.00 54.93  ? 626  GLU A C   1 
ATOM   3805  O O   . GLU A 1 626 ? 143.784 175.801 112.761 1.00 54.93  ? 626  GLU A O   1 
ATOM   3806  C CB  . GLU A 1 626 ? 143.053 174.984 109.576 1.00 54.93  ? 626  GLU A CB  1 
ATOM   3807  C CG  . GLU A 1 626 ? 142.895 173.616 110.193 1.00 54.93  ? 626  GLU A CG  1 
ATOM   3808  C CD  . GLU A 1 626 ? 142.040 172.705 109.340 1.00 54.93  ? 626  GLU A CD  1 
ATOM   3809  O OE1 . GLU A 1 626 ? 141.569 173.162 108.279 1.00 54.93  ? 626  GLU A OE1 1 
ATOM   3810  O OE2 . GLU A 1 626 ? 141.835 171.537 109.724 1.00 54.93  ? 626  GLU A OE2 1 
ATOM   3811  N N   . THR A 1 627 ? 142.248 177.060 111.681 1.00 53.83  ? 627  THR A N   1 
ATOM   3812  C CA  . THR A 1 627 ? 141.559 177.548 112.868 1.00 53.83  ? 627  THR A CA  1 
ATOM   3813  C C   . THR A 1 627 ? 140.736 176.461 113.549 1.00 53.83  ? 627  THR A C   1 
ATOM   3814  O O   . THR A 1 627 ? 140.628 176.468 114.781 1.00 53.83  ? 627  THR A O   1 
ATOM   3815  C CB  . THR A 1 627 ? 140.681 178.744 112.459 1.00 53.83  ? 627  THR A CB  1 
ATOM   3816  O OG1 . THR A 1 627 ? 141.517 179.777 111.927 1.00 53.83  ? 627  THR A OG1 1 
ATOM   3817  C CG2 . THR A 1 627 ? 139.893 179.334 113.631 1.00 53.83  ? 627  THR A CG2 1 
ATOM   3818  N N   . SER A 1 628 ? 140.222 175.488 112.789 1.00 44.99  ? 628  SER A N   1 
ATOM   3819  C CA  . SER A 1 628 ? 139.325 174.484 113.355 1.00 44.99  ? 628  SER A CA  1 
ATOM   3820  C C   . SER A 1 628 ? 140.039 173.538 114.316 1.00 44.99  ? 628  SER A C   1 
ATOM   3821  O O   . SER A 1 628 ? 139.386 172.907 115.152 1.00 44.99  ? 628  SER A O   1 
ATOM   3822  C CB  . SER A 1 628 ? 138.657 173.689 112.240 1.00 44.99  ? 628  SER A CB  1 
ATOM   3823  O OG  . SER A 1 628 ? 137.801 172.699 112.779 1.00 44.99  ? 628  SER A OG  1 
ATOM   3824  N N   . HIS A 1 629 ? 141.360 173.420 114.221 1.00 43.00  ? 629  HIS A N   1 
ATOM   3825  C CA  . HIS A 1 629 ? 142.116 172.748 115.275 1.00 43.00  ? 629  HIS A CA  1 
ATOM   3826  C C   . HIS A 1 629 ? 142.644 173.744 116.299 1.00 43.00  ? 629  HIS A C   1 
ATOM   3827  O O   . HIS A 1 629 ? 143.809 173.730 116.678 1.00 43.00  ? 629  HIS A O   1 
ATOM   3828  C CB  . HIS A 1 629 ? 143.246 171.941 114.660 1.00 43.00  ? 629  HIS A CB  1 
ATOM   3829  C CG  . HIS A 1 629 ? 142.803 171.073 113.530 1.00 43.00  ? 629  HIS A CG  1 
ATOM   3830  N ND1 . HIS A 1 629 ? 141.617 170.372 113.555 1.00 43.00  ? 629  HIS A ND1 1 
ATOM   3831  C CD2 . HIS A 1 629 ? 143.371 170.809 112.332 1.00 43.00  ? 629  HIS A CD2 1 
ATOM   3832  C CE1 . HIS A 1 629 ? 141.478 169.705 112.424 1.00 43.00  ? 629  HIS A CE1 1 
ATOM   3833  N NE2 . HIS A 1 629 ? 142.529 169.955 111.663 1.00 43.00  ? 629  HIS A NE2 1 
ATOM   3834  N N   . LEU A 1 630 ? 141.759 174.634 116.738 1.00 35.46  ? 630  LEU A N   1 
ATOM   3835  C CA  . LEU A 1 630 ? 141.946 175.455 117.923 1.00 35.46  ? 630  LEU A CA  1 
ATOM   3836  C C   . LEU A 1 630 ? 140.678 175.531 118.738 1.00 35.46  ? 630  LEU A C   1 
ATOM   3837  O O   . LEU A 1 630 ? 140.749 175.786 119.941 1.00 35.46  ? 630  LEU A O   1 
ATOM   3838  C CB  . LEU A 1 630 ? 142.386 176.877 117.554 1.00 35.46  ? 630  LEU A CB  1 
ATOM   3839  C CG  . LEU A 1 630 ? 143.845 177.086 117.159 1.00 35.46  ? 630  LEU A CG  1 
ATOM   3840  C CD1 . LEU A 1 630 ? 144.062 178.498 116.652 1.00 35.46  ? 630  LEU A CD1 1 
ATOM   3841  C CD2 . LEU A 1 630 ? 144.758 176.794 118.331 1.00 35.46  ? 630  LEU A CD2 1 
ATOM   3842  N N   . VAL A 1 631 ? 139.520 175.324 118.118 1.00 28.11  ? 631  VAL A N   1 
ATOM   3843  C CA  . VAL A 1 631 ? 138.275 175.140 118.840 1.00 28.11  ? 631  VAL A CA  1 
ATOM   3844  C C   . VAL A 1 631 ? 138.091 173.674 119.221 1.00 28.11  ? 631  VAL A C   1 
ATOM   3845  O O   . VAL A 1 631 ? 137.332 173.370 120.156 1.00 28.11  ? 631  VAL A O   1 
ATOM   3846  C CB  . VAL A 1 631 ? 137.100 175.672 117.992 1.00 28.11  ? 631  VAL A CB  1 
ATOM   3847  C CG1 . VAL A 1 631 ? 135.840 175.865 118.810 1.00 28.11  ? 631  VAL A CG1 1 
ATOM   3848  C CG2 . VAL A 1 631 ? 137.495 176.962 117.326 1.00 28.11  ? 631  VAL A CG2 1 
ATOM   3849  N N   . ASN A 1 632 ? 138.804 172.761 118.558 1.00 23.60  ? 632  ASN A N   1 
ATOM   3850  C CA  . ASN A 1 632 ? 138.919 171.391 119.047 1.00 23.60  ? 632  ASN A CA  1 
ATOM   3851  C C   . ASN A 1 632 ? 139.721 171.349 120.337 1.00 23.60  ? 632  ASN A C   1 
ATOM   3852  O O   . ASN A 1 632 ? 139.363 170.636 121.279 1.00 23.60  ? 632  ASN A O   1 
ATOM   3853  C CB  . ASN A 1 632 ? 139.582 170.515 117.987 1.00 23.60  ? 632  ASN A CB  1 
ATOM   3854  C CG  . ASN A 1 632 ? 139.184 169.068 118.096 1.00 23.60  ? 632  ASN A CG  1 
ATOM   3855  O OD1 . ASN A 1 632 ? 139.432 168.419 119.104 1.00 23.60  ? 632  ASN A OD1 1 
ATOM   3856  N ND2 . ASN A 1 632 ? 138.577 168.548 117.047 1.00 23.60  ? 632  ASN A ND2 1 
ATOM   3857  N N   . LEU A 1 633 ? 140.817 172.113 120.387 1.00 21.88  ? 633  LEU A N   1 
ATOM   3858  C CA  . LEU A 1 633 ? 141.665 172.203 121.574 1.00 21.88  ? 633  LEU A CA  1 
ATOM   3859  C C   . LEU A 1 633 ? 140.903 172.785 122.750 1.00 21.88  ? 633  LEU A C   1 
ATOM   3860  O O   . LEU A 1 633 ? 141.157 172.439 123.904 1.00 21.88  ? 633  LEU A O   1 
ATOM   3861  C CB  . LEU A 1 633 ? 142.898 173.059 121.270 1.00 21.88  ? 633  LEU A CB  1 
ATOM   3862  C CG  . LEU A 1 633 ? 143.971 173.273 122.338 1.00 21.88  ? 633  LEU A CG  1 
ATOM   3863  C CD1 . LEU A 1 633 ? 145.342 173.153 121.712 1.00 21.88  ? 633  LEU A CD1 1 
ATOM   3864  C CD2 . LEU A 1 633 ? 143.834 174.628 123.005 1.00 21.88  ? 633  LEU A CD2 1 
ATOM   3865  N N   . GLY A 1 634 ? 139.974 173.685 122.469 1.00 20.10  ? 634  GLY A N   1 
ATOM   3866  C CA  . GLY A 1 634 ? 139.169 174.279 123.506 1.00 20.10  ? 634  GLY A CA  1 
ATOM   3867  C C   . GLY A 1 634 ? 138.210 173.296 124.136 1.00 20.10  ? 634  GLY A C   1 
ATOM   3868  O O   . GLY A 1 634 ? 137.789 173.500 125.279 1.00 20.10  ? 634  GLY A O   1 
ATOM   3869  N N   . LYS A 1 635 ? 137.862 172.227 123.409 1.00 16.29  ? 635  LYS A N   1 
ATOM   3870  C CA  . LYS A 1 635 ? 136.788 171.337 123.845 1.00 16.29  ? 635  LYS A CA  1 
ATOM   3871  C C   . LYS A 1 635 ? 137.197 170.473 125.030 1.00 16.29  ? 635  LYS A C   1 
ATOM   3872  O O   . LYS A 1 635 ? 136.352 170.122 125.864 1.00 16.29  ? 635  LYS A O   1 
ATOM   3873  C CB  . LYS A 1 635 ? 136.337 170.469 122.677 1.00 16.29  ? 635  LYS A CB  1 
ATOM   3874  C CG  . LYS A 1 635 ? 135.093 169.652 122.931 1.00 16.29  ? 635  LYS A CG  1 
ATOM   3875  C CD  . LYS A 1 635 ? 134.758 168.822 121.724 1.00 16.29  ? 635  LYS A CD  1 
ATOM   3876  C CE  . LYS A 1 635 ? 135.320 167.427 121.810 1.00 16.29  ? 635  LYS A CE  1 
ATOM   3877  N NZ  . LYS A 1 635 ? 134.479 166.475 121.038 1.00 16.29  ? 635  LYS A NZ  1 
ATOM   3878  N N   . TYR A 1 636 ? 138.477 170.126 125.128 1.00 20.76  ? 636  TYR A N   1 
ATOM   3879  C CA  . TYR A 1 636 ? 138.960 169.293 126.214 1.00 20.76  ? 636  TYR A CA  1 
ATOM   3880  C C   . TYR A 1 636 ? 139.448 170.118 127.396 1.00 20.76  ? 636  TYR A C   1 
ATOM   3881  O O   . TYR A 1 636 ? 139.410 169.658 128.538 1.00 20.76  ? 636  TYR A O   1 
ATOM   3882  C CB  . TYR A 1 636 ? 140.064 168.381 125.689 1.00 20.76  ? 636  TYR A CB  1 
ATOM   3883  C CG  . TYR A 1 636 ? 139.643 167.644 124.448 1.00 20.76  ? 636  TYR A CG  1 
ATOM   3884  C CD1 . TYR A 1 636 ? 138.724 166.611 124.509 1.00 20.76  ? 636  TYR A CD1 1 
ATOM   3885  C CD2 . TYR A 1 636 ? 140.128 168.009 123.214 1.00 20.76  ? 636  TYR A CD2 1 
ATOM   3886  C CE1 . TYR A 1 636 ? 138.329 165.952 123.382 1.00 20.76  ? 636  TYR A CE1 1 
ATOM   3887  C CE2 . TYR A 1 636 ? 139.727 167.360 122.084 1.00 20.76  ? 636  TYR A CE2 1 
ATOM   3888  C CZ  . TYR A 1 636 ? 138.831 166.334 122.173 1.00 20.76  ? 636  TYR A CZ  1 
ATOM   3889  O OH  . TYR A 1 636 ? 138.441 165.689 121.031 1.00 20.76  ? 636  TYR A OH  1 
ATOM   3890  N N   . VAL A 1 637 ? 139.886 171.347 127.142 1.00 12.89  ? 637  VAL A N   1 
ATOM   3891  C CA  . VAL A 1 637 ? 140.221 172.303 128.189 1.00 12.89  ? 637  VAL A CA  1 
ATOM   3892  C C   . VAL A 1 637 ? 138.920 172.716 128.860 1.00 12.89  ? 637  VAL A C   1 
ATOM   3893  O O   . VAL A 1 637 ? 138.894 173.010 130.058 1.00 12.89  ? 637  VAL A O   1 
ATOM   3894  C CB  . VAL A 1 637 ? 140.996 173.502 127.611 1.00 12.89  ? 637  VAL A CB  1 
ATOM   3895  C CG1 . VAL A 1 637 ? 141.324 174.527 128.661 1.00 12.89  ? 637  VAL A CG1 1 
ATOM   3896  C CG2 . VAL A 1 637 ? 142.279 173.020 126.982 1.00 12.89  ? 637  VAL A CG2 1 
ATOM   3897  N N   . SER A 1 638 ? 137.821 172.690 128.109 1.00 14.77  ? 638  SER A N   1 
ATOM   3898  C CA  . SER A 1 638 ? 136.505 172.914 128.687 1.00 14.77  ? 638  SER A CA  1 
ATOM   3899  C C   . SER A 1 638 ? 136.113 171.872 129.722 1.00 14.77  ? 638  SER A C   1 
ATOM   3900  O O   . SER A 1 638 ? 135.658 172.242 130.809 1.00 14.77  ? 638  SER A O   1 
ATOM   3901  C CB  . SER A 1 638 ? 135.441 172.933 127.606 1.00 14.77  ? 638  SER A CB  1 
ATOM   3902  O OG  . SER A 1 638 ? 134.175 173.088 128.200 1.00 14.77  ? 638  SER A OG  1 
ATOM   3903  N N   . ALA A 1 639 ? 136.265 170.584 129.428 1.00 19.51  ? 639  ALA A N   1 
ATOM   3904  C CA  . ALA A 1 639 ? 136.042 169.554 130.447 1.00 19.51  ? 639  ALA A CA  1 
ATOM   3905  C C   . ALA A 1 639 ? 137.336 169.157 131.148 1.00 19.51  ? 639  ALA A C   1 
ATOM   3906  O O   . ALA A 1 639 ? 137.653 167.987 131.316 1.00 19.51  ? 639  ALA A O   1 
ATOM   3907  C CB  . ALA A 1 639 ? 135.371 168.342 129.822 1.00 19.51  ? 639  ALA A CB  1 
ATOM   3908  N N   . MET A 1 640 ? 138.069 170.140 131.564 1.00 19.20  ? 640  MET A N   1 
ATOM   3909  C CA  . MET A 1 640 ? 139.188 170.079 132.488 1.00 19.20  ? 640  MET A CA  1 
ATOM   3910  C C   . MET A 1 640 ? 139.096 171.200 133.501 1.00 19.20  ? 640  MET A C   1 
ATOM   3911  O O   . MET A 1 640 ? 139.673 171.102 134.582 1.00 19.20  ? 640  MET A O   1 
ATOM   3912  C CB  . MET A 1 640 ? 140.524 170.150 131.746 1.00 19.20  ? 640  MET A CB  1 
ATOM   3913  C CG  . MET A 1 640 ? 141.029 168.817 131.263 1.00 19.20  ? 640  MET A CG  1 
ATOM   3914  S SD  . MET A 1 640 ? 142.816 168.656 131.371 1.00 19.20  ? 640  MET A SD  1 
ATOM   3915  C CE  . MET A 1 640 ? 143.334 169.402 129.839 1.00 19.20  ? 640  MET A CE  1 
ATOM   3916  N N   . LEU A 1 641 ? 138.383 172.266 133.166 1.00 24.02  ? 641  LEU A N   1 
ATOM   3917  C CA  . LEU A 1 641 ? 137.984 173.281 134.116 1.00 24.02  ? 641  LEU A CA  1 
ATOM   3918  C C   . LEU A 1 641 ? 136.679 172.934 134.798 1.00 24.02  ? 641  LEU A C   1 
ATOM   3919  O O   . LEU A 1 641 ? 136.526 173.219 135.988 1.00 24.02  ? 641  LEU A O   1 
ATOM   3920  C CB  . LEU A 1 641 ? 137.850 174.632 133.419 1.00 24.02  ? 641  LEU A CB  1 
ATOM   3921  C CG  . LEU A 1 641 ? 139.066 175.147 132.660 1.00 24.02  ? 641  LEU A CG  1 
ATOM   3922  C CD1 . LEU A 1 641 ? 138.826 176.573 132.232 1.00 24.02  ? 641  LEU A CD1 1 
ATOM   3923  C CD2 . LEU A 1 641 ? 140.315 175.049 133.509 1.00 24.02  ? 641  LEU A CD2 1 
ATOM   3924  N N   . ALA A 1 642 ? 135.746 172.304 134.082 1.00 27.76  ? 642  ALA A N   1 
ATOM   3925  C CA  . ALA A 1 642 ? 134.446 171.966 134.639 1.00 27.76  ? 642  ALA A CA  1 
ATOM   3926  C C   . ALA A 1 642 ? 134.507 170.909 135.728 1.00 27.76  ? 642  ALA A C   1 
ATOM   3927  O O   . ALA A 1 642 ? 133.635 170.893 136.600 1.00 27.76  ? 642  ALA A O   1 
ATOM   3928  C CB  . ALA A 1 642 ? 133.499 171.484 133.535 1.00 27.76  ? 642  ALA A CB  1 
ATOM   3929  N N   . ALA A 1 643 ? 135.506 170.036 135.702 1.00 32.29  ? 643  ALA A N   1 
ATOM   3930  C CA  . ALA A 1 643 ? 135.802 169.191 136.843 1.00 32.29  ? 643  ALA A CA  1 
ATOM   3931  C C   . ALA A 1 643 ? 136.887 169.774 137.728 1.00 32.29  ? 643  ALA A C   1 
ATOM   3932  O O   . ALA A 1 643 ? 137.021 169.352 138.879 1.00 32.29  ? 643  ALA A O   1 
ATOM   3933  C CB  . ALA A 1 643 ? 136.220 167.801 136.381 1.00 32.29  ? 643  ALA A CB  1 
ATOM   3934  N N   . GLY A 1 644 ? 137.651 170.743 137.221 1.00 35.01  ? 644  GLY A N   1 
ATOM   3935  C CA  . GLY A 1 644 ? 138.570 171.486 138.061 1.00 35.01  ? 644  GLY A CA  1 
ATOM   3936  C C   . GLY A 1 644 ? 137.888 172.400 139.056 1.00 35.01  ? 644  GLY A C   1 
ATOM   3937  O O   . GLY A 1 644 ? 138.527 172.834 140.019 1.00 35.01  ? 644  GLY A O   1 
ATOM   3938  N N   . THR A 1 645 ? 136.607 172.712 138.842 1.00 38.37  ? 645  THR A N   1 
ATOM   3939  C CA  . THR A 1 645 ? 135.838 173.423 139.852 1.00 38.37  ? 645  THR A CA  1 
ATOM   3940  C C   . THR A 1 645 ? 135.356 172.490 140.958 1.00 38.37  ? 645  THR A C   1 
ATOM   3941  O O   . THR A 1 645 ? 135.112 172.945 142.080 1.00 38.37  ? 645  THR A O   1 
ATOM   3942  C CB  . THR A 1 645 ? 134.647 174.137 139.214 1.00 38.37  ? 645  THR A CB  1 
ATOM   3943  O OG1 . THR A 1 645 ? 133.845 173.189 138.505 1.00 38.37  ? 645  THR A OG1 1 
ATOM   3944  C CG2 . THR A 1 645 ? 135.116 175.211 138.255 1.00 38.37  ? 645  THR A CG2 1 
ATOM   3945  N N   . LYS A 1 646 ? 135.215 171.192 140.673 1.00 39.66  ? 646  LYS A N   1 
ATOM   3946  C CA  . LYS A 1 646 ? 134.883 170.241 141.728 1.00 39.66  ? 646  LYS A CA  1 
ATOM   3947  C C   . LYS A 1 646 ? 136.058 170.011 142.664 1.00 39.66  ? 646  LYS A C   1 
ATOM   3948  O O   . LYS A 1 646 ? 135.851 169.624 143.819 1.00 39.66  ? 646  LYS A O   1 
ATOM   3949  C CB  . LYS A 1 646 ? 134.417 168.915 141.122 1.00 39.66  ? 646  LYS A CB  1 
ATOM   3950  C CG  . LYS A 1 646 ? 133.724 167.963 142.095 1.00 39.66  ? 646  LYS A CG  1 
ATOM   3951  C CD  . LYS A 1 646 ? 132.344 168.455 142.474 1.00 39.66  ? 646  LYS A CD  1 
ATOM   3952  C CE  . LYS A 1 646 ? 131.332 168.115 141.404 1.00 39.66  ? 646  LYS A CE  1 
ATOM   3953  N NZ  . LYS A 1 646 ? 130.129 168.982 141.456 1.00 39.66  ? 646  LYS A NZ  1 
ATOM   3954  N N   . VAL A 1 647 ? 137.282 170.249 142.188 1.00 42.03  ? 647  VAL A N   1 
ATOM   3955  C CA  . VAL A 1 647 ? 138.450 170.250 143.063 1.00 42.03  ? 647  VAL A CA  1 
ATOM   3956  C C   . VAL A 1 647 ? 138.316 171.339 144.121 1.00 42.03  ? 647  VAL A C   1 
ATOM   3957  O O   . VAL A 1 647 ? 138.640 171.130 145.297 1.00 42.03  ? 647  VAL A O   1 
ATOM   3958  C CB  . VAL A 1 647 ? 139.730 170.406 142.217 1.00 42.03  ? 647  VAL A CB  1 
ATOM   3959  C CG1 . VAL A 1 647 ? 140.944 170.738 143.072 1.00 42.03  ? 647  VAL A CG1 1 
ATOM   3960  C CG2 . VAL A 1 647 ? 139.987 169.136 141.427 1.00 42.03  ? 647  VAL A CG2 1 
ATOM   3961  N N   . ALA A 1 648 ? 137.776 172.491 143.739 1.00 47.69  ? 648  ALA A N   1 
ATOM   3962  C CA  . ALA A 1 648 ? 137.496 173.560 144.684 1.00 47.69  ? 648  ALA A CA  1 
ATOM   3963  C C   . ALA A 1 648 ? 136.031 173.615 145.099 1.00 47.69  ? 648  ALA A C   1 
ATOM   3964  O O   . ALA A 1 648 ? 135.516 174.703 145.367 1.00 47.69  ? 648  ALA A O   1 
ATOM   3965  C CB  . ALA A 1 648 ? 137.925 174.903 144.098 1.00 47.69  ? 648  ALA A CB  1 
ATOM   3966  N N   . TYR A 1 649 ? 135.343 172.477 145.134 1.00 48.13  ? 649  TYR A N   1 
ATOM   3967  C CA  . TYR A 1 649 ? 133.996 172.410 145.678 1.00 48.13  ? 649  TYR A CA  1 
ATOM   3968  C C   . TYR A 1 649 ? 133.906 171.560 146.941 1.00 48.13  ? 649  TYR A C   1 
ATOM   3969  O O   . TYR A 1 649 ? 132.957 171.729 147.715 1.00 48.13  ? 649  TYR A O   1 
ATOM   3970  C CB  . TYR A 1 649 ? 133.020 171.882 144.613 1.00 48.13  ? 649  TYR A CB  1 
ATOM   3971  C CG  . TYR A 1 649 ? 131.582 171.794 145.070 1.00 48.13  ? 649  TYR A CG  1 
ATOM   3972  C CD1 . TYR A 1 649 ? 130.919 170.575 145.099 1.00 48.13  ? 649  TYR A CD1 1 
ATOM   3973  C CD2 . TYR A 1 649 ? 130.904 172.920 145.514 1.00 48.13  ? 649  TYR A CD2 1 
ATOM   3974  C CE1 . TYR A 1 649 ? 129.609 170.482 145.528 1.00 48.13  ? 649  TYR A CE1 1 
ATOM   3975  C CE2 . TYR A 1 649 ? 129.594 172.840 145.945 1.00 48.13  ? 649  TYR A CE2 1 
ATOM   3976  C CZ  . TYR A 1 649 ? 128.953 171.616 145.950 1.00 48.13  ? 649  TYR A CZ  1 
ATOM   3977  O OH  . TYR A 1 649 ? 127.652 171.515 146.378 1.00 48.13  ? 649  TYR A OH  1 
ATOM   3978  N N   . GLU A 1 650 ? 134.886 170.682 147.187 1.00 52.51  ? 650  GLU A N   1 
ATOM   3979  C CA  . GLU A 1 650 ? 134.916 169.904 148.425 1.00 52.51  ? 650  GLU A CA  1 
ATOM   3980  C C   . GLU A 1 650 ? 135.069 170.807 149.643 1.00 52.51  ? 650  GLU A C   1 
ATOM   3981  O O   . GLU A 1 650 ? 134.552 170.507 150.725 1.00 52.51  ? 650  GLU A O   1 
ATOM   3982  C CB  . GLU A 1 650 ? 136.043 168.875 148.360 1.00 52.51  ? 650  GLU A CB  1 
ATOM   3983  C CG  . GLU A 1 650 ? 137.347 169.417 147.792 1.00 52.51  ? 650  GLU A CG  1 
ATOM   3984  C CD  . GLU A 1 650 ? 138.235 170.058 148.837 1.00 52.51  ? 650  GLU A CD  1 
ATOM   3985  O OE1 . GLU A 1 650 ? 138.043 169.776 150.038 1.00 52.51  ? 650  GLU A OE1 1 
ATOM   3986  O OE2 . GLU A 1 650 ? 139.121 170.850 148.457 1.00 52.51  ? 650  GLU A OE2 1 
ATOM   3987  N N   . LYS A 1 651 ? 135.772 171.918 149.479 1.00 51.10  ? 651  LYS A N   1 
ATOM   3988  C CA  . LYS A 1 651 ? 135.745 173.025 150.416 1.00 51.10  ? 651  LYS A CA  1 
ATOM   3989  C C   . LYS A 1 651 ? 134.839 174.112 149.859 1.00 51.10  ? 651  LYS A C   1 
ATOM   3990  O O   . LYS A 1 651 ? 134.436 174.064 148.696 1.00 51.10  ? 651  LYS A O   1 
ATOM   3991  C CB  . LYS A 1 651 ? 137.153 173.568 150.650 1.00 51.10  ? 651  LYS A CB  1 
ATOM   3992  C CG  . LYS A 1 651 ? 137.924 173.816 149.369 1.00 51.10  ? 651  LYS A CG  1 
ATOM   3993  C CD  . LYS A 1 651 ? 139.198 174.584 149.636 1.00 51.10  ? 651  LYS A CD  1 
ATOM   3994  C CE  . LYS A 1 651 ? 138.888 175.940 150.239 1.00 51.10  ? 651  LYS A CE  1 
ATOM   3995  N NZ  . LYS A 1 651 ? 140.070 176.836 150.214 1.00 51.10  ? 651  LYS A NZ  1 
ATOM   3996  N N   . GLU A 1 652 ? 134.526 175.094 150.723 1.00 56.03  ? 652  GLU A N   1 
ATOM   3997  C CA  . GLU A 1 652 ? 133.707 176.293 150.436 1.00 56.03  ? 652  GLU A CA  1 
ATOM   3998  C C   . GLU A 1 652 ? 132.416 175.962 149.679 1.00 56.03  ? 652  GLU A C   1 
ATOM   3999  O O   . GLU A 1 652 ? 131.990 176.681 148.773 1.00 56.03  ? 652  GLU A O   1 
ATOM   4000  C CB  . GLU A 1 652 ? 134.528 177.407 149.754 1.00 56.03  ? 652  GLU A CB  1 
ATOM   4001  C CG  . GLU A 1 652 ? 135.182 177.161 148.395 1.00 56.03  ? 652  GLU A CG  1 
ATOM   4002  C CD  . GLU A 1 652 ? 136.157 178.252 148.020 1.00 56.03  ? 652  GLU A CD  1 
ATOM   4003  O OE1 . GLU A 1 652 ? 136.286 179.227 148.785 1.00 56.03  ? 652  GLU A OE1 1 
ATOM   4004  O OE2 . GLU A 1 652 ? 136.827 178.121 146.974 1.00 56.03  ? 652  GLU A OE2 1 
ATOM   4005  N N   . ARG A 1 653 ? 131.788 174.857 150.086 1.00 57.51  ? 653  ARG A N   1 
ATOM   4006  C CA  . ARG A 1 653 ? 130.508 174.406 149.552 1.00 57.51  ? 653  ARG A CA  1 
ATOM   4007  C C   . ARG A 1 653 ? 129.430 175.382 149.995 1.00 57.51  ? 653  ARG A C   1 
ATOM   4008  O O   . ARG A 1 653 ? 128.965 175.330 151.137 1.00 57.51  ? 653  ARG A O   1 
ATOM   4009  C CB  . ARG A 1 653 ? 130.222 172.997 150.059 1.00 57.51  ? 653  ARG A CB  1 
ATOM   4010  C CG  . ARG A 1 653 ? 129.013 172.297 149.466 1.00 57.51  ? 653  ARG A CG  1 
ATOM   4011  C CD  . ARG A 1 653 ? 128.632 171.111 150.345 1.00 57.51  ? 653  ARG A CD  1 
ATOM   4012  N NE  . ARG A 1 653 ? 127.729 170.170 149.688 1.00 57.51  ? 653  ARG A NE  1 
ATOM   4013  C CZ  . ARG A 1 653 ? 128.086 168.956 149.282 1.00 57.51  ? 653  ARG A CZ  1 
ATOM   4014  N NH1 . ARG A 1 653 ? 129.328 168.530 149.468 1.00 57.51  ? 653  ARG A NH1 1 
ATOM   4015  N NH2 . ARG A 1 653 ? 127.201 168.163 148.695 1.00 57.51  ? 653  ARG A NH2 1 
ATOM   4016  N N   . SER A 1 654 ? 129.037 176.273 149.095 1.00 53.90  ? 654  SER A N   1 
ATOM   4017  C CA  . SER A 1 654 ? 128.292 177.467 149.460 1.00 53.90  ? 654  SER A CA  1 
ATOM   4018  C C   . SER A 1 654 ? 127.552 177.951 148.219 1.00 53.90  ? 654  SER A C   1 
ATOM   4019  O O   . SER A 1 654 ? 127.320 177.176 147.286 1.00 53.90  ? 654  SER A O   1 
ATOM   4020  C CB  . SER A 1 654 ? 129.244 178.526 150.034 1.00 53.90  ? 654  SER A CB  1 
ATOM   4021  O OG  . SER A 1 654 ? 130.410 178.626 149.235 1.00 53.90  ? 654  SER A OG  1 
ATOM   4022  N N   . LEU A 1 655 ? 127.154 179.223 148.216 1.00 55.79  ? 655  LEU A N   1 
ATOM   4023  C CA  . LEU A 1 655 ? 126.759 179.897 146.985 1.00 55.79  ? 655  LEU A CA  1 
ATOM   4024  C C   . LEU A 1 655 ? 127.954 180.573 146.309 1.00 55.79  ? 655  LEU A C   1 
ATOM   4025  O O   . LEU A 1 655 ? 127.810 181.610 145.649 1.00 55.79  ? 655  LEU A O   1 
ATOM   4026  C CB  . LEU A 1 655 ? 125.636 180.899 147.272 1.00 55.79  ? 655  LEU A CB  1 
ATOM   4027  C CG  . LEU A 1 655 ? 124.644 181.266 146.155 1.00 55.79  ? 655  LEU A CG  1 
ATOM   4028  C CD1 . LEU A 1 655 ? 123.910 180.034 145.634 1.00 55.79  ? 655  LEU A CD1 1 
ATOM   4029  C CD2 . LEU A 1 655 ? 123.665 182.331 146.627 1.00 55.79  ? 655  LEU A CD2 1 
ATOM   4030  N N   . GLY A 1 656 ? 129.142 180.003 146.478 1.00 57.29  ? 656  GLY A N   1 
ATOM   4031  C CA  . GLY A 1 656 ? 130.364 180.466 145.857 1.00 57.29  ? 656  GLY A CA  1 
ATOM   4032  C C   . GLY A 1 656 ? 130.688 179.604 144.657 1.00 57.29  ? 656  GLY A C   1 
ATOM   4033  O O   . GLY A 1 656 ? 130.179 179.843 143.559 1.00 57.29  ? 656  GLY A O   1 
ATOM   4034  N N   . TRP A 1 657 ? 131.534 178.592 144.846 1.00 57.14  ? 657  TRP A N   1 
ATOM   4035  C CA  . TRP A 1 657 ? 131.907 177.677 143.767 1.00 57.14  ? 657  TRP A CA  1 
ATOM   4036  C C   . TRP A 1 657 ? 130.880 176.546 143.618 1.00 57.14  ? 657  TRP A C   1 
ATOM   4037  O O   . TRP A 1 657 ? 131.210 175.366 143.538 1.00 57.14  ? 657  TRP A O   1 
ATOM   4038  C CB  . TRP A 1 657 ? 133.301 177.109 144.018 1.00 57.14  ? 657  TRP A CB  1 
ATOM   4039  C CG  . TRP A 1 657 ? 134.447 178.104 144.123 1.00 57.14  ? 657  TRP A CG  1 
ATOM   4040  C CD1 . TRP A 1 657 ? 134.594 179.106 145.043 1.00 57.14  ? 657  TRP A CD1 1 
ATOM   4041  C CD2 . TRP A 1 657 ? 135.636 178.129 143.323 1.00 57.14  ? 657  TRP A CD2 1 
ATOM   4042  N NE1 . TRP A 1 657 ? 135.774 179.773 144.840 1.00 57.14  ? 657  TRP A NE1 1 
ATOM   4043  C CE2 . TRP A 1 657 ? 136.436 179.191 143.793 1.00 57.14  ? 657  TRP A CE2 1 
ATOM   4044  C CE3 . TRP A 1 657 ? 136.092 177.370 142.243 1.00 57.14  ? 657  TRP A CE3 1 
ATOM   4045  C CZ2 . TRP A 1 657 ? 137.664 179.509 143.221 1.00 57.14  ? 657  TRP A CZ2 1 
ATOM   4046  C CZ3 . TRP A 1 657 ? 137.314 177.685 141.679 1.00 57.14  ? 657  TRP A CZ3 1 
ATOM   4047  C CH2 . TRP A 1 657 ? 138.085 178.745 142.167 1.00 57.14  ? 657  TRP A CH2 1 
ATOM   4048  N N   . LEU A 1 658 ? 129.608 176.939 143.563 1.00 53.38  ? 658  LEU A N   1 
ATOM   4049  C CA  . LEU A 1 658 ? 128.497 176.063 143.212 1.00 53.38  ? 658  LEU A CA  1 
ATOM   4050  C C   . LEU A 1 658 ? 127.576 176.692 142.184 1.00 53.38  ? 658  LEU A C   1 
ATOM   4051  O O   . LEU A 1 658 ? 126.854 175.965 141.492 1.00 53.38  ? 658  LEU A O   1 
ATOM   4052  C CB  . LEU A 1 658 ? 127.693 175.683 144.464 1.00 53.38  ? 658  LEU A CB  1 
ATOM   4053  C CG  . LEU A 1 658 ? 126.503 174.717 144.457 1.00 53.38  ? 658  LEU A CG  1 
ATOM   4054  C CD1 . LEU A 1 658 ? 126.805 173.442 143.698 1.00 53.38  ? 658  LEU A CD1 1 
ATOM   4055  C CD2 . LEU A 1 658 ? 126.089 174.409 145.882 1.00 53.38  ? 658  LEU A CD2 1 
ATOM   4056  N N   . CYS A 1 659 ? 127.607 178.015 142.030 1.00 54.08  ? 659  CYS A N   1 
ATOM   4057  C CA  . CYS A 1 659 ? 127.191 178.671 140.801 1.00 54.08  ? 659  CYS A CA  1 
ATOM   4058  C C   . CYS A 1 659 ? 128.316 178.708 139.773 1.00 54.08  ? 659  CYS A C   1 
ATOM   4059  O O   . CYS A 1 659 ? 128.202 179.407 138.761 1.00 54.08  ? 659  CYS A O   1 
ATOM   4060  C CB  . CYS A 1 659 ? 126.696 180.089 141.095 1.00 54.08  ? 659  CYS A CB  1 
ATOM   4061  S SG  . CYS A 1 659 ? 127.984 181.236 141.632 1.00 54.08  ? 659  CYS A SG  1 
ATOM   4062  N N   . LEU A 1 660 ? 129.407 177.982 140.032 1.00 50.06  ? 660  LEU A N   1 
ATOM   4063  C CA  . LEU A 1 660 ? 130.496 177.795 139.091 1.00 50.06  ? 660  LEU A CA  1 
ATOM   4064  C C   . LEU A 1 660 ? 130.574 176.373 138.551 1.00 50.06  ? 660  LEU A C   1 
ATOM   4065  O O   . LEU A 1 660 ? 130.931 176.197 137.382 1.00 50.06  ? 660  LEU A O   1 
ATOM   4066  C CB  . LEU A 1 660 ? 131.837 178.158 139.751 1.00 50.06  ? 660  LEU A CB  1 
ATOM   4067  C CG  . LEU A 1 660 ? 132.925 178.818 138.903 1.00 50.06  ? 660  LEU A CG  1 
ATOM   4068  C CD1 . LEU A 1 660 ? 132.376 180.027 138.175 1.00 50.06  ? 660  LEU A CD1 1 
ATOM   4069  C CD2 . LEU A 1 660 ? 134.101 179.218 139.771 1.00 50.06  ? 660  LEU A CD2 1 
ATOM   4070  N N   . VAL A 1 661 ? 130.232 175.358 139.352 1.00 45.10  ? 661  VAL A N   1 
ATOM   4071  C CA  . VAL A 1 661 ? 130.190 173.983 138.869 1.00 45.10  ? 661  VAL A CA  1 
ATOM   4072  C C   . VAL A 1 661 ? 128.861 173.675 138.187 1.00 45.10  ? 661  VAL A C   1 
ATOM   4073  O O   . VAL A 1 661 ? 128.660 172.560 137.687 1.00 45.10  ? 661  VAL A O   1 
ATOM   4074  C CB  . VAL A 1 661 ? 130.482 173.020 140.043 1.00 45.10  ? 661  VAL A CB  1 
ATOM   4075  C CG1 . VAL A 1 661 ? 129.263 172.853 140.927 1.00 45.10  ? 661  VAL A CG1 1 
ATOM   4076  C CG2 . VAL A 1 661 ? 131.070 171.683 139.576 1.00 45.10  ? 661  VAL A CG2 1 
ATOM   4077  N N   . VAL A 1 662 ? 127.942 174.633 138.141 1.00 48.16  ? 662  VAL A N   1 
ATOM   4078  C CA  . VAL A 1 662 ? 126.762 174.514 137.296 1.00 48.16  ? 662  VAL A CA  1 
ATOM   4079  C C   . VAL A 1 662 ? 127.054 175.371 136.071 1.00 48.16  ? 662  VAL A C   1 
ATOM   4080  O O   . VAL A 1 662 ? 126.582 175.092 134.963 1.00 48.16  ? 662  VAL A O   1 
ATOM   4081  C CB  . VAL A 1 662 ? 125.492 174.945 138.054 1.00 48.16  ? 662  VAL A CB  1 
ATOM   4082  C CG1 . VAL A 1 662 ? 124.266 174.997 137.152 1.00 48.16  ? 662  VAL A CG1 1 
ATOM   4083  C CG2 . VAL A 1 662 ? 125.244 174.005 139.212 1.00 48.16  ? 662  VAL A CG2 1 
ATOM   4084  N N   . ALA A 1 663 ? 127.905 176.381 136.255 1.00 49.17  ? 663  ALA A N   1 
ATOM   4085  C CA  . ALA A 1 663 ? 128.275 177.265 135.156 1.00 49.17  ? 663  ALA A CA  1 
ATOM   4086  C C   . ALA A 1 663 ? 129.182 176.567 134.149 1.00 49.17  ? 663  ALA A C   1 
ATOM   4087  O O   . ALA A 1 663 ? 128.826 176.425 132.976 1.00 49.17  ? 663  ALA A O   1 
ATOM   4088  C CB  . ALA A 1 663 ? 128.958 178.520 135.698 1.00 49.17  ? 663  ALA A CB  1 
ATOM   4089  N N   . MET A 1 664 ? 130.359 176.120 134.594 1.00 44.85  ? 664  MET A N   1 
ATOM   4090  C CA  . MET A 1 664 ? 131.330 175.567 133.656 1.00 44.85  ? 664  MET A CA  1 
ATOM   4091  C C   . MET A 1 664 ? 130.950 174.167 133.201 1.00 44.85  ? 664  MET A C   1 
ATOM   4092  O O   . MET A 1 664 ? 131.416 173.716 132.153 1.00 44.85  ? 664  MET A O   1 
ATOM   4093  C CB  . MET A 1 664 ? 132.721 175.550 134.280 1.00 44.85  ? 664  MET A CB  1 
ATOM   4094  C CG  . MET A 1 664 ? 133.230 176.912 134.686 1.00 44.85  ? 664  MET A CG  1 
ATOM   4095  S SD  . MET A 1 664 ? 133.283 178.055 133.303 1.00 44.85  ? 664  MET A SD  1 
ATOM   4096  C CE  . MET A 1 664 ? 133.936 179.518 134.095 1.00 44.85  ? 664  MET A CE  1 
ATOM   4097  N N   . SER A 1 665 ? 130.108 173.470 133.954 1.00 37.53  ? 665  SER A N   1 
ATOM   4098  C CA  . SER A 1 665 ? 129.746 172.119 133.568 1.00 37.53  ? 665  SER A CA  1 
ATOM   4099  C C   . SER A 1 665 ? 128.592 172.072 132.585 1.00 37.53  ? 665  SER A C   1 
ATOM   4100  O O   . SER A 1 665 ? 128.348 171.014 132.003 1.00 37.53  ? 665  SER A O   1 
ATOM   4101  C CB  . SER A 1 665 ? 129.384 171.293 134.791 1.00 37.53  ? 665  SER A CB  1 
ATOM   4102  O OG  . SER A 1 665 ? 128.143 171.712 135.321 1.00 37.53  ? 665  SER A OG  1 
ATOM   4103  N N   . SER A 1 666 ? 127.871 173.171 132.386 1.00 32.47  ? 666  SER A N   1 
ATOM   4104  C CA  . SER A 1 666 ? 126.920 173.249 131.288 1.00 32.47  ? 666  SER A CA  1 
ATOM   4105  C C   . SER A 1 666 ? 127.466 174.030 130.107 1.00 32.47  ? 666  SER A C   1 
ATOM   4106  O O   . SER A 1 666 ? 126.924 173.914 129.005 1.00 32.47  ? 666  SER A O   1 
ATOM   4107  C CB  . SER A 1 666 ? 125.600 173.868 131.752 1.00 32.47  ? 666  SER A CB  1 
ATOM   4108  O OG  . SER A 1 666 ? 124.770 172.880 132.333 1.00 32.47  ? 666  SER A OG  1 
ATOM   4109  N N   . VAL A 1 667 ? 128.514 174.827 130.321 1.00 29.52  ? 667  VAL A N   1 
ATOM   4110  C CA  . VAL A 1 667 ? 129.310 175.341 129.212 1.00 29.52  ? 667  VAL A CA  1 
ATOM   4111  C C   . VAL A 1 667 ? 129.973 174.187 128.476 1.00 29.52  ? 667  VAL A C   1 
ATOM   4112  O O   . VAL A 1 667 ? 130.015 174.157 127.242 1.00 29.52  ? 667  VAL A O   1 
ATOM   4113  C CB  . VAL A 1 667 ? 130.338 176.366 129.730 1.00 29.52  ? 667  VAL A CB  1 
ATOM   4114  C CG1 . VAL A 1 667 ? 131.500 176.559 128.757 1.00 29.52  ? 667  VAL A CG1 1 
ATOM   4115  C CG2 . VAL A 1 667 ? 129.654 177.694 130.000 1.00 29.52  ? 667  VAL A CG2 1 
ATOM   4116  N N   . ALA A 1 668 ? 130.460 173.196 129.227 1.00 19.37  ? 668  ALA A N   1 
ATOM   4117  C CA  . ALA A 1 668 ? 131.095 172.033 128.618 1.00 19.37  ? 668  ALA A CA  1 
ATOM   4118  C C   . ALA A 1 668 ? 130.096 171.193 127.842 1.00 19.37  ? 668  ALA A C   1 
ATOM   4119  O O   . ALA A 1 668 ? 130.345 170.847 126.687 1.00 19.37  ? 668  ALA A O   1 
ATOM   4120  C CB  . ALA A 1 668 ? 131.775 171.182 129.686 1.00 19.37  ? 668  ALA A CB  1 
ATOM   4121  N N   . THR A 1 669 ? 128.929 170.926 128.424 1.00 21.64  ? 669  THR A N   1 
ATOM   4122  C CA  . THR A 1 669 ? 128.034 169.914 127.879 1.00 21.64  ? 669  THR A CA  1 
ATOM   4123  C C   . THR A 1 669 ? 127.307 170.390 126.619 1.00 21.64  ? 669  THR A C   1 
ATOM   4124  O O   . THR A 1 669 ? 126.678 169.581 125.934 1.00 21.64  ? 669  THR A O   1 
ATOM   4125  C CB  . THR A 1 669 ? 127.065 169.499 128.986 1.00 21.64  ? 669  THR A CB  1 
ATOM   4126  O OG1 . THR A 1 669 ? 127.810 169.364 130.195 1.00 21.64  ? 669  THR A OG1 1 
ATOM   4127  C CG2 . THR A 1 669 ? 126.443 168.133 128.728 1.00 21.64  ? 669  THR A CG2 1 
ATOM   4128  N N   . ILE A 1 670 ? 127.418 171.666 126.257 1.00 22.73  ? 670  ILE A N   1 
ATOM   4129  C CA  . ILE A 1 670 ? 127.011 172.092 124.919 1.00 22.73  ? 670  ILE A CA  1 
ATOM   4130  C C   . ILE A 1 670 ? 128.207 172.113 123.972 1.00 22.73  ? 670  ILE A C   1 
ATOM   4131  O O   . ILE A 1 670 ? 128.100 171.725 122.808 1.00 22.73  ? 670  ILE A O   1 
ATOM   4132  C CB  . ILE A 1 670 ? 126.287 173.463 124.980 1.00 22.73  ? 670  ILE A CB  1 
ATOM   4133  C CG1 . ILE A 1 670 ? 125.967 174.001 123.582 1.00 22.73  ? 670  ILE A CG1 1 
ATOM   4134  C CG2 . ILE A 1 670 ? 127.075 174.499 125.779 1.00 22.73  ? 670  ILE A CG2 1 
ATOM   4135  C CD1 . ILE A 1 670 ? 124.987 173.162 122.791 1.00 22.73  ? 670  ILE A CD1 1 
ATOM   4136  N N   . TYR A 1 671 ? 129.376 172.494 124.478 1.00 15.99  ? 671  TYR A N   1 
ATOM   4137  C CA  . TYR A 1 671 ? 130.593 172.590 123.692 1.00 15.99  ? 671  TYR A CA  1 
ATOM   4138  C C   . TYR A 1 671 ? 131.178 171.231 123.354 1.00 15.99  ? 671  TYR A C   1 
ATOM   4139  O O   . TYR A 1 671 ? 132.054 171.149 122.492 1.00 15.99  ? 671  TYR A O   1 
ATOM   4140  C CB  . TYR A 1 671 ? 131.549 173.480 124.461 1.00 15.99  ? 671  TYR A CB  1 
ATOM   4141  C CG  . TYR A 1 671 ? 132.817 173.856 123.790 1.00 15.99  ? 671  TYR A CG  1 
ATOM   4142  C CD1 . TYR A 1 671 ? 132.830 174.252 122.475 1.00 15.99  ? 671  TYR A CD1 1 
ATOM   4143  C CD2 . TYR A 1 671 ? 133.956 174.033 124.529 1.00 15.99  ? 671  TYR A CD2 1 
ATOM   4144  C CE1 . TYR A 1 671 ? 133.985 174.656 121.881 1.00 15.99  ? 671  TYR A CE1 1 
ATOM   4145  C CE2 . TYR A 1 671 ? 135.094 174.465 123.959 1.00 15.99  ? 671  TYR A CE2 1 
ATOM   4146  C CZ  . TYR A 1 671 ? 135.114 174.762 122.632 1.00 15.99  ? 671  TYR A CZ  1 
ATOM   4147  O OH  . TYR A 1 671 ? 136.277 175.186 122.055 1.00 15.99  ? 671  TYR A OH  1 
ATOM   4148  N N   . GLN A 1 672 ? 130.728 170.170 124.014 1.00 14.39  ? 672  GLN A N   1 
ATOM   4149  C CA  . GLN A 1 672 ? 130.868 168.836 123.461 1.00 14.39  ? 672  GLN A CA  1 
ATOM   4150  C C   . GLN A 1 672 ? 129.700 168.452 122.574 1.00 14.39  ? 672  GLN A C   1 
ATOM   4151  O O   . GLN A 1 672 ? 129.906 167.749 121.588 1.00 14.39  ? 672  GLN A O   1 
ATOM   4152  C CB  . GLN A 1 672 ? 131.002 167.791 124.570 1.00 14.39  ? 672  GLN A CB  1 
ATOM   4153  C CG  . GLN A 1 672 ? 131.860 168.197 125.744 1.00 14.39  ? 672  GLN A CG  1 
ATOM   4154  C CD  . GLN A 1 672 ? 133.310 167.876 125.552 1.00 14.39  ? 672  GLN A CD  1 
ATOM   4155  O OE1 . GLN A 1 672 ? 133.648 166.900 124.909 1.00 14.39  ? 672  GLN A OE1 1 
ATOM   4156  N NE2 . GLN A 1 672 ? 134.182 168.692 126.118 1.00 14.39  ? 672  GLN A NE2 1 
ATOM   4157  N N   . LEU A 1 673 ? 128.481 168.894 122.893 1.00 17.03  ? 673  LEU A N   1 
ATOM   4158  C CA  . LEU A 1 673 ? 127.303 168.602 122.078 1.00 17.03  ? 673  LEU A CA  1 
ATOM   4159  C C   . LEU A 1 673 ? 127.271 169.347 120.758 1.00 17.03  ? 673  LEU A C   1 
ATOM   4160  O O   . LEU A 1 673 ? 126.646 168.860 119.812 1.00 17.03  ? 673  LEU A O   1 
ATOM   4161  C CB  . LEU A 1 673 ? 126.024 168.938 122.832 1.00 17.03  ? 673  LEU A CB  1 
ATOM   4162  C CG  . LEU A 1 673 ? 125.172 167.850 123.453 1.00 17.03  ? 673  LEU A CG  1 
ATOM   4163  C CD1 . LEU A 1 673 ? 124.406 167.174 122.377 1.00 17.03  ? 673  LEU A CD1 1 
ATOM   4164  C CD2 . LEU A 1 673 ? 126.035 166.853 124.086 1.00 17.03  ? 673  LEU A CD2 1 
ATOM   4165  N N   . TYR A 1 674 ? 127.870 170.530 120.685 1.00 19.72  ? 674  TYR A N   1 
ATOM   4166  C CA  . TYR A 1 674 ? 127.998 171.227 119.408 1.00 19.72  ? 674  TYR A CA  1 
ATOM   4167  C C   . TYR A 1 674 ? 128.927 170.452 118.483 1.00 19.72  ? 674  TYR A C   1 
ATOM   4168  O O   . TYR A 1 674 ? 128.556 170.099 117.362 1.00 19.72  ? 674  TYR A O   1 
ATOM   4169  C CB  . TYR A 1 674 ? 128.510 172.651 119.647 1.00 19.72  ? 674  TYR A CB  1 
ATOM   4170  C CG  . TYR A 1 674 ? 129.232 173.275 118.477 1.00 19.72  ? 674  TYR A CG  1 
ATOM   4171  C CD1 . TYR A 1 674 ? 128.550 173.620 117.320 1.00 19.72  ? 674  TYR A CD1 1 
ATOM   4172  C CD2 . TYR A 1 674 ? 130.594 173.533 118.540 1.00 19.72  ? 674  TYR A CD2 1 
ATOM   4173  C CE1 . TYR A 1 674 ? 129.202 174.188 116.260 1.00 19.72  ? 674  TYR A CE1 1 
ATOM   4174  C CE2 . TYR A 1 674 ? 131.254 174.104 117.484 1.00 19.72  ? 674  TYR A CE2 1 
ATOM   4175  C CZ  . TYR A 1 674 ? 130.551 174.429 116.347 1.00 19.72  ? 674  TYR A CZ  1 
ATOM   4176  O OH  . TYR A 1 674 ? 131.199 175.001 115.282 1.00 19.72  ? 674  TYR A OH  1 
ATOM   4177  N N   . TRP A 1 675 ? 130.133 170.167 118.963 1.00 17.74  ? 675  TRP A N   1 
ATOM   4178  C CA  . TRP A 1 675 ? 131.210 169.585 118.180 1.00 17.74  ? 675  TRP A CA  1 
ATOM   4179  C C   . TRP A 1 675 ? 130.918 168.187 117.679 1.00 17.74  ? 675  TRP A C   1 
ATOM   4180  O O   . TRP A 1 675 ? 131.496 167.755 116.680 1.00 17.74  ? 675  TRP A O   1 
ATOM   4181  C CB  . TRP A 1 675 ? 132.470 169.537 119.016 1.00 17.74  ? 675  TRP A CB  1 
ATOM   4182  C CG  . TRP A 1 675 ? 133.687 169.477 118.226 1.00 17.74  ? 675  TRP A CG  1 
ATOM   4183  C CD1 . TRP A 1 675 ? 134.354 168.368 117.822 1.00 17.74  ? 675  TRP A CD1 1 
ATOM   4184  C CD2 . TRP A 1 675 ? 134.410 170.584 117.741 1.00 17.74  ? 675  TRP A CD2 1 
ATOM   4185  N NE1 . TRP A 1 675 ? 135.459 168.721 117.104 1.00 17.74  ? 675  TRP A NE1 1 
ATOM   4186  C CE2 . TRP A 1 675 ? 135.515 170.086 117.040 1.00 17.74  ? 675  TRP A CE2 1 
ATOM   4187  C CE3 . TRP A 1 675 ? 134.231 171.960 117.829 1.00 17.74  ? 675  TRP A CE3 1 
ATOM   4188  C CZ2 . TRP A 1 675 ? 136.429 170.916 116.417 1.00 17.74  ? 675  TRP A CZ2 1 
ATOM   4189  C CZ3 . TRP A 1 675 ? 135.133 172.776 117.219 1.00 17.74  ? 675  TRP A CZ3 1 
ATOM   4190  C CH2 . TRP A 1 675 ? 136.228 172.259 116.528 1.00 17.74  ? 675  TRP A CH2 1 
ATOM   4191  N N   . ASP A 1 676 ? 130.058 167.462 118.388 1.00 22.94  ? 676  ASP A N   1 
ATOM   4192  C CA  . ASP A 1 676 ? 129.744 166.098 117.997 1.00 22.94  ? 676  ASP A CA  1 
ATOM   4193  C C   . ASP A 1 676 ? 128.981 166.075 116.687 1.00 22.94  ? 676  ASP A C   1 
ATOM   4194  O O   . ASP A 1 676 ? 129.414 165.448 115.717 1.00 22.94  ? 676  ASP A O   1 
ATOM   4195  C CB  . ASP A 1 676 ? 128.952 165.412 119.097 1.00 22.94  ? 676  ASP A CB  1 
ATOM   4196  C CG  . ASP A 1 676 ? 129.834 164.898 120.205 1.00 22.94  ? 676  ASP A CG  1 
ATOM   4197  O OD1 . ASP A 1 676 ? 131.045 165.200 120.204 1.00 22.94  ? 676  ASP A OD1 1 
ATOM   4198  O OD2 . ASP A 1 676 ? 129.316 164.182 121.078 1.00 22.94  ? 676  ASP A OD2 1 
ATOM   4199  N N   . PHE A 1 677 ? 127.865 166.800 116.622 1.00 19.07  ? 677  PHE A N   1 
ATOM   4200  C CA  . PHE A 1 677 ? 127.064 166.824 115.403 1.00 19.07  ? 677  PHE A CA  1 
ATOM   4201  C C   . PHE A 1 677 ? 127.681 167.665 114.298 1.00 19.07  ? 677  PHE A C   1 
ATOM   4202  O O   . PHE A 1 677 ? 127.569 167.304 113.123 1.00 19.07  ? 677  PHE A O   1 
ATOM   4203  C CB  . PHE A 1 677 ? 125.670 167.348 115.704 1.00 19.07  ? 677  PHE A CB  1 
ATOM   4204  C CG  . PHE A 1 677 ? 124.971 166.576 116.745 1.00 19.07  ? 677  PHE A CG  1 
ATOM   4205  C CD1 . PHE A 1 677 ? 124.626 165.268 116.526 1.00 19.07  ? 677  PHE A CD1 1 
ATOM   4206  C CD2 . PHE A 1 677 ? 124.683 167.147 117.956 1.00 19.07  ? 677  PHE A CD2 1 
ATOM   4207  C CE1 . PHE A 1 677 ? 123.986 164.545 117.492 1.00 19.07  ? 677  PHE A CE1 1 
ATOM   4208  C CE2 . PHE A 1 677 ? 124.043 166.432 118.923 1.00 19.07  ? 677  PHE A CE2 1 
ATOM   4209  C CZ  . PHE A 1 677 ? 123.696 165.126 118.692 1.00 19.07  ? 677  PHE A CZ  1 
ATOM   4210  N N   . VAL A 1 678 ? 128.325 168.770 114.636 1.00 21.87  ? 678  VAL A N   1 
ATOM   4211  C CA  . VAL A 1 678 ? 128.710 169.710 113.603 1.00 21.87  ? 678  VAL A CA  1 
ATOM   4212  C C   . VAL A 1 678 ? 130.043 169.303 113.005 1.00 21.87  ? 678  VAL A C   1 
ATOM   4213  O O   . VAL A 1 678 ? 130.126 169.023 111.807 1.00 21.87  ? 678  VAL A O   1 
ATOM   4214  C CB  . VAL A 1 678 ? 128.749 171.143 114.146 1.00 21.87  ? 678  VAL A CB  1 
ATOM   4215  C CG1 . VAL A 1 678 ? 129.292 172.077 113.095 1.00 21.87  ? 678  VAL A CG1 1 
ATOM   4216  C CG2 . VAL A 1 678 ? 127.358 171.559 114.550 1.00 21.87  ? 678  VAL A CG2 1 
ATOM   4217  N N   . LYS A 1 679 ? 131.094 169.251 113.814 1.00 18.74  ? 679  LYS A N   1 
ATOM   4218  C CA  . LYS A 1 679 ? 132.427 169.093 113.255 1.00 18.74  ? 679  LYS A CA  1 
ATOM   4219  C C   . LYS A 1 679 ? 132.982 167.686 113.393 1.00 18.74  ? 679  LYS A C   1 
ATOM   4220  O O   . LYS A 1 679 ? 134.125 167.446 112.990 1.00 18.74  ? 679  LYS A O   1 
ATOM   4221  C CB  . LYS A 1 679 ? 133.381 170.101 113.881 1.00 18.74  ? 679  LYS A CB  1 
ATOM   4222  C CG  . LYS A 1 679 ? 133.211 171.478 113.305 1.00 18.74  ? 679  LYS A CG  1 
ATOM   4223  C CD  . LYS A 1 679 ? 134.486 172.264 113.380 1.00 18.74  ? 679  LYS A CD  1 
ATOM   4224  C CE  . LYS A 1 679 ? 134.302 173.611 112.731 1.00 18.74  ? 679  LYS A CE  1 
ATOM   4225  N NZ  . LYS A 1 679 ? 133.004 174.219 113.132 1.00 18.74  ? 679  LYS A NZ  1 
ATOM   4226  N N   . ASP A 1 680 ? 132.214 166.752 113.953 1.00 22.53  ? 680  ASP A N   1 
ATOM   4227  C CA  . ASP A 1 680 ? 132.594 165.344 113.936 1.00 22.53  ? 680  ASP A CA  1 
ATOM   4228  C C   . ASP A 1 680 ? 131.635 164.503 113.118 1.00 22.53  ? 680  ASP A C   1 
ATOM   4229  O O   . ASP A 1 680 ? 132.063 163.847 112.168 1.00 22.53  ? 680  ASP A O   1 
ATOM   4230  C CB  . ASP A 1 680 ? 132.697 164.784 115.361 1.00 22.53  ? 680  ASP A CB  1 
ATOM   4231  C CG  . ASP A 1 680 ? 134.102 164.880 115.917 1.00 22.53  ? 680  ASP A CG  1 
ATOM   4232  O OD1 . ASP A 1 680 ? 135.019 165.198 115.137 1.00 22.53  ? 680  ASP A OD1 1 
ATOM   4233  O OD2 . ASP A 1 680 ? 134.298 164.646 117.125 1.00 22.53  ? 680  ASP A OD2 1 
ATOM   4234  N N   . TRP A 1 681 ? 130.344 164.523 113.430 1.00 32.32  ? 681  TRP A N   1 
ATOM   4235  C CA  . TRP A 1 681 ? 129.396 163.755 112.639 1.00 32.32  ? 681  TRP A CA  1 
ATOM   4236  C C   . TRP A 1 681 ? 129.060 164.439 111.327 1.00 32.32  ? 681  TRP A C   1 
ATOM   4237  O O   . TRP A 1 681 ? 128.530 163.787 110.424 1.00 32.32  ? 681  TRP A O   1 
ATOM   4238  C CB  . TRP A 1 681 ? 128.094 163.496 113.408 1.00 32.32  ? 681  TRP A CB  1 
ATOM   4239  C CG  . TRP A 1 681 ? 128.212 162.687 114.685 1.00 32.32  ? 681  TRP A CG  1 
ATOM   4240  C CD1 . TRP A 1 681 ? 129.347 162.379 115.372 1.00 32.32  ? 681  TRP A CD1 1 
ATOM   4241  C CD2 . TRP A 1 681 ? 127.137 162.103 115.427 1.00 32.32  ? 681  TRP A CD2 1 
ATOM   4242  N NE1 . TRP A 1 681 ? 129.048 161.653 116.485 1.00 32.32  ? 681  TRP A NE1 1 
ATOM   4243  C CE2 . TRP A 1 681 ? 127.696 161.466 116.541 1.00 32.32  ? 681  TRP A CE2 1 
ATOM   4244  C CE3 . TRP A 1 681 ? 125.755 162.059 115.255 1.00 32.32  ? 681  TRP A CE3 1 
ATOM   4245  C CZ2 . TRP A 1 681 ? 126.932 160.796 117.471 1.00 32.32  ? 681  TRP A CZ2 1 
ATOM   4246  C CZ3 . TRP A 1 681 ? 124.999 161.388 116.183 1.00 32.32  ? 681  TRP A CZ3 1 
ATOM   4247  C CH2 . TRP A 1 681 ? 125.590 160.767 117.274 1.00 32.32  ? 681  TRP A CH2 1 
ATOM   4248  N N   . GLY A 1 682 ? 129.353 165.732 111.205 1.00 29.66  ? 682  GLY A N   1 
ATOM   4249  C CA  . GLY A 1 682 ? 129.084 166.481 109.998 1.00 29.66  ? 682  GLY A CA  1 
ATOM   4250  C C   . GLY A 1 682 ? 127.647 166.892 109.809 1.00 29.66  ? 682  GLY A C   1 
ATOM   4251  O O   . GLY A 1 682 ? 127.308 167.423 108.748 1.00 29.66  ? 682  GLY A O   1 
ATOM   4252  N N   . LEU A 1 683 ? 126.797 166.677 110.800 1.00 39.87  ? 683  LEU A N   1 
ATOM   4253  C CA  . LEU A 1 683 ? 125.368 166.882 110.647 1.00 39.87  ? 683  LEU A CA  1 
ATOM   4254  C C   . LEU A 1 683 ? 125.010 168.329 110.977 1.00 39.87  ? 683  LEU A C   1 
ATOM   4255  O O   . LEU A 1 683 ? 125.884 169.193 111.085 1.00 39.87  ? 683  LEU A O   1 
ATOM   4256  C CB  . LEU A 1 683 ? 124.610 165.890 111.520 1.00 39.87  ? 683  LEU A CB  1 
ATOM   4257  C CG  . LEU A 1 683 ? 124.864 164.439 111.139 1.00 39.87  ? 683  LEU A CG  1 
ATOM   4258  C CD1 . LEU A 1 683 ? 124.275 163.510 112.171 1.00 39.87  ? 683  LEU A CD1 1 
ATOM   4259  C CD2 . LEU A 1 683 ? 124.274 164.163 109.781 1.00 39.87  ? 683  LEU A CD2 1 
ATOM   4260  N N   . LEU A 1 684 ? 123.701 168.588 111.118 1.00 47.39  ? 684  LEU A N   1 
ATOM   4261  C CA  . LEU A 1 684 ? 123.128 169.891 111.480 1.00 47.39  ? 684  LEU A CA  1 
ATOM   4262  C C   . LEU A 1 684 ? 123.511 170.984 110.486 1.00 47.39  ? 684  LEU A C   1 
ATOM   4263  O O   . LEU A 1 684 ? 124.001 172.049 110.865 1.00 47.39  ? 684  LEU A O   1 
ATOM   4264  C CB  . LEU A 1 684 ? 123.502 170.303 112.907 1.00 47.39  ? 684  LEU A CB  1 
ATOM   4265  C CG  . LEU A 1 684 ? 122.817 169.576 114.059 1.00 47.39  ? 684  LEU A CG  1 
ATOM   4266  C CD1 . LEU A 1 684 ? 123.057 170.328 115.346 1.00 47.39  ? 684  LEU A CD1 1 
ATOM   4267  C CD2 . LEU A 1 684 ? 121.339 169.440 113.802 1.00 47.39  ? 684  LEU A CD2 1 
ATOM   4268  N N   . GLN A 1 685 ? 123.290 170.724 109.206 1.00 61.47  ? 685  GLN A N   1 
ATOM   4269  C CA  . GLN A 1 685 ? 123.489 171.722 108.165 1.00 61.47  ? 685  GLN A CA  1 
ATOM   4270  C C   . GLN A 1 685 ? 122.120 172.155 107.654 1.00 61.47  ? 685  GLN A C   1 
ATOM   4271  O O   . GLN A 1 685 ? 121.441 171.390 106.963 1.00 61.47  ? 685  GLN A O   1 
ATOM   4272  C CB  . GLN A 1 685 ? 124.357 171.167 107.040 1.00 61.47  ? 685  GLN A CB  1 
ATOM   4273  C CG  . GLN A 1 685 ? 125.737 170.746 107.500 1.00 61.47  ? 685  GLN A CG  1 
ATOM   4274  C CD  . GLN A 1 685 ? 126.678 170.467 106.349 1.00 61.47  ? 685  GLN A CD  1 
ATOM   4275  O OE1 . GLN A 1 685 ? 126.322 170.649 105.185 1.00 61.47  ? 685  GLN A OE1 1 
ATOM   4276  N NE2 . GLN A 1 685 ? 127.887 170.022 106.668 1.00 61.47  ? 685  GLN A NE2 1 
ATOM   4277  N N   . HIS A 1 686 ? 121.712 173.381 108.007 1.00 62.71  ? 686  HIS A N   1 
ATOM   4278  C CA  . HIS A 1 686 ? 120.423 173.906 107.564 1.00 62.71  ? 686  HIS A CA  1 
ATOM   4279  C C   . HIS A 1 686 ? 120.390 174.169 106.067 1.00 62.71  ? 686  HIS A C   1 
ATOM   4280  O O   . HIS A 1 686 ? 119.316 174.120 105.458 1.00 62.71  ? 686  HIS A O   1 
ATOM   4281  C CB  . HIS A 1 686 ? 120.080 175.197 108.312 1.00 62.71  ? 686  HIS A CB  1 
ATOM   4282  C CG  . HIS A 1 686 ? 119.386 174.976 109.620 1.00 62.71  ? 686  HIS A CG  1 
ATOM   4283  N ND1 . HIS A 1 686 ? 119.121 176.002 110.501 1.00 62.71  ? 686  HIS A ND1 1 
ATOM   4284  C CD2 . HIS A 1 686 ? 118.898 173.852 110.195 1.00 62.71  ? 686  HIS A CD2 1 
ATOM   4285  C CE1 . HIS A 1 686 ? 118.502 175.519 111.563 1.00 62.71  ? 686  HIS A CE1 1 
ATOM   4286  N NE2 . HIS A 1 686 ? 118.356 174.217 111.403 1.00 62.71  ? 686  HIS A NE2 1 
ATOM   4287  N N   . ASN A 1 687 ? 121.544 174.440 105.458 1.00 60.16  ? 687  ASN A N   1 
ATOM   4288  C CA  . ASN A 1 687 ? 121.629 174.663 104.016 1.00 60.16  ? 687  ASN A CA  1 
ATOM   4289  C C   . ASN A 1 687 ? 121.770 173.310 103.317 1.00 60.16  ? 687  ASN A C   1 
ATOM   4290  O O   . ASN A 1 687 ? 122.807 172.959 102.750 1.00 60.16  ? 687  ASN A O   1 
ATOM   4291  C CB  . ASN A 1 687 ? 122.789 175.594 103.692 1.00 60.16  ? 687  ASN A CB  1 
ATOM   4292  C CG  . ASN A 1 687 ? 122.862 176.789 104.631 1.00 60.16  ? 687  ASN A CG  1 
ATOM   4293  O OD1 . ASN A 1 687 ? 123.933 177.132 105.134 1.00 60.16  ? 687  ASN A OD1 1 
ATOM   4294  N ND2 . ASN A 1 687 ? 121.723 177.434 104.862 1.00 60.16  ? 687  ASN A ND2 1 
ATOM   4295  N N   . SER A 1 688 ? 120.687 172.538 103.373 1.00 58.53  ? 688  SER A N   1 
ATOM   4296  C CA  . SER A 1 688 ? 120.658 171.183 102.836 1.00 58.53  ? 688  SER A CA  1 
ATOM   4297  C C   . SER A 1 688 ? 119.235 170.859 102.411 1.00 58.53  ? 688  SER A C   1 
ATOM   4298  O O   . SER A 1 688 ? 118.299 171.622 102.659 1.00 58.53  ? 688  SER A O   1 
ATOM   4299  C CB  . SER A 1 688 ? 121.150 170.149 103.857 1.00 58.53  ? 688  SER A CB  1 
ATOM   4300  O OG  . SER A 1 688 ? 122.373 170.528 104.462 1.00 58.53  ? 688  SER A OG  1 
ATOM   4301  N N   . ASN A 1 689 ? 119.087 169.707 101.763 1.00 56.95  ? 689  ASN A N   1 
ATOM   4302  C CA  . ASN A 1 689 ? 117.783 169.200 101.366 1.00 56.95  ? 689  ASN A CA  1 
ATOM   4303  C C   . ASN A 1 689 ? 117.139 168.331 102.437 1.00 56.95  ? 689  ASN A C   1 
ATOM   4304  O O   . ASN A 1 689 ? 115.998 167.894 102.258 1.00 56.95  ? 689  ASN A O   1 
ATOM   4305  C CB  . ASN A 1 689 ? 117.905 168.405 100.066 1.00 56.95  ? 689  ASN A CB  1 
ATOM   4306  C CG  . ASN A 1 689 ? 118.999 167.364 100.126 1.00 56.95  ? 689  ASN A CG  1 
ATOM   4307  O OD1 . ASN A 1 689 ? 120.060 167.599 100.702 1.00 56.95  ? 689  ASN A OD1 1 
ATOM   4308  N ND2 . ASN A 1 689 ? 118.747 166.204 99.535  1.00 56.95  ? 689  ASN A ND2 1 
ATOM   4309  N N   . ASN A 1 690 ? 117.835 168.077 103.538 1.00 57.04  ? 690  ASN A N   1 
ATOM   4310  C CA  . ASN A 1 690 ? 117.334 167.259 104.627 1.00 57.04  ? 690  ASN A CA  1 
ATOM   4311  C C   . ASN A 1 690 ? 117.261 168.093 105.896 1.00 57.04  ? 690  ASN A C   1 
ATOM   4312  O O   . ASN A 1 690 ? 118.185 168.857 106.194 1.00 57.04  ? 690  ASN A O   1 
ATOM   4313  C CB  . ASN A 1 690 ? 118.234 166.039 104.860 1.00 57.04  ? 690  ASN A CB  1 
ATOM   4314  C CG  . ASN A 1 690 ? 117.903 164.887 103.936 1.00 57.04  ? 690  ASN A CG  1 
ATOM   4315  O OD1 . ASN A 1 690 ? 116.738 164.547 103.745 1.00 57.04  ? 690  ASN A OD1 1 
ATOM   4316  N ND2 . ASN A 1 690 ? 118.929 164.284 103.348 1.00 57.04  ? 690  ASN A ND2 1 
ATOM   4317  N N   . PRO A 1 691 ? 116.164 167.977 106.659 1.00 60.97  ? 691  PRO A N   1 
ATOM   4318  C CA  . PRO A 1 691 ? 116.039 168.763 107.894 1.00 60.97  ? 691  PRO A CA  1 
ATOM   4319  C C   . PRO A 1 691 ? 116.980 168.273 108.979 1.00 60.97  ? 691  PRO A C   1 
ATOM   4320  O O   . PRO A 1 691 ? 116.904 167.114 109.396 1.00 60.97  ? 691  PRO A O   1 
ATOM   4321  C CB  . PRO A 1 691 ? 114.569 168.573 108.289 1.00 60.97  ? 691  PRO A CB  1 
ATOM   4322  C CG  . PRO A 1 691 ? 114.158 167.299 107.645 1.00 60.97  ? 691  PRO A CG  1 
ATOM   4323  C CD  . PRO A 1 691 ? 114.962 167.170 106.385 1.00 60.97  ? 691  PRO A CD  1 
ATOM   4324  N N   . TRP A 1 692 ? 117.911 169.139 109.387 1.00 64.80  ? 692  TRP A N   1 
ATOM   4325  C CA  . TRP A 1 692 ? 118.895 168.958 110.456 1.00 64.80  ? 692  TRP A CA  1 
ATOM   4326  C C   . TRP A 1 692 ? 119.912 167.848 110.191 1.00 64.80  ? 692  TRP A C   1 
ATOM   4327  O O   . TRP A 1 692 ? 120.684 167.518 111.094 1.00 64.80  ? 692  TRP A O   1 
ATOM   4328  C CB  . TRP A 1 692 ? 118.234 168.717 111.821 1.00 64.80  ? 692  TRP A CB  1 
ATOM   4329  C CG  . TRP A 1 692 ? 117.430 169.887 112.298 1.00 64.80  ? 692  TRP A CG  1 
ATOM   4330  C CD1 . TRP A 1 692 ? 117.497 171.167 111.835 1.00 64.80  ? 692  TRP A CD1 1 
ATOM   4331  C CD2 . TRP A 1 692 ? 116.449 169.889 113.341 1.00 64.80  ? 692  TRP A CD2 1 
ATOM   4332  N NE1 . TRP A 1 692 ? 116.615 171.966 112.521 1.00 64.80  ? 692  TRP A NE1 1 
ATOM   4333  C CE2 . TRP A 1 692 ? 115.960 171.205 113.452 1.00 64.80  ? 692  TRP A CE2 1 
ATOM   4334  C CE3 . TRP A 1 692 ? 115.935 168.905 114.192 1.00 64.80  ? 692  TRP A CE3 1 
ATOM   4335  C CZ2 . TRP A 1 692 ? 114.982 171.564 114.377 1.00 64.80  ? 692  TRP A CZ2 1 
ATOM   4336  C CZ3 . TRP A 1 692 ? 114.965 169.263 115.111 1.00 64.80  ? 692  TRP A CZ3 1 
ATOM   4337  C CH2 . TRP A 1 692 ? 114.498 170.581 115.196 1.00 64.80  ? 692  TRP A CH2 1 
ATOM   4338  N N   . LEU A 1 693 ? 119.939 167.261 108.997 1.00 54.79  ? 693  LEU A N   1 
ATOM   4339  C CA  . LEU A 1 693 ? 120.987 166.354 108.560 1.00 54.79  ? 693  LEU A CA  1 
ATOM   4340  C C   . LEU A 1 693 ? 121.791 167.025 107.451 1.00 54.79  ? 693  LEU A C   1 
ATOM   4341  O O   . LEU A 1 693 ? 121.592 168.201 107.135 1.00 54.79  ? 693  LEU A O   1 
ATOM   4342  C CB  . LEU A 1 693 ? 120.388 165.028 108.097 1.00 54.79  ? 693  LEU A CB  1 
ATOM   4343  C CG  . LEU A 1 693 ? 119.502 164.309 109.107 1.00 54.79  ? 693  LEU A CG  1 
ATOM   4344  C CD1 . LEU A 1 693 ? 119.000 163.007 108.533 1.00 54.79  ? 693  LEU A CD1 1 
ATOM   4345  C CD2 . LEU A 1 693 ? 120.270 164.064 110.377 1.00 54.79  ? 693  LEU A CD2 1 
ATOM   4346  N N   . ARG A 1 694 ? 122.710 166.283 106.847 1.00 41.83  ? 694  ARG A N   1 
ATOM   4347  C CA  . ARG A 1 694 ? 123.505 166.802 105.748 1.00 41.83  ? 694  ARG A CA  1 
ATOM   4348  C C   . ARG A 1 694 ? 122.850 166.439 104.421 1.00 41.83  ? 694  ARG A C   1 
ATOM   4349  O O   . ARG A 1 694 ? 121.703 165.983 104.374 1.00 41.83  ? 694  ARG A O   1 
ATOM   4350  C CB  . ARG A 1 694 ? 124.939 166.283 105.824 1.00 41.83  ? 694  ARG A CB  1 
ATOM   4351  C CG  . ARG A 1 694 ? 125.062 164.782 105.944 1.00 41.83  ? 694  ARG A CG  1 
ATOM   4352  C CD  . ARG A 1 694 ? 126.507 164.412 106.164 1.00 41.83  ? 694  ARG A CD  1 
ATOM   4353  N NE  . ARG A 1 694 ? 126.676 163.101 106.773 1.00 41.83  ? 694  ARG A NE  1 
ATOM   4354  C CZ  . ARG A 1 694 ? 127.769 162.754 107.438 1.00 41.83  ? 694  ARG A CZ  1 
ATOM   4355  N NH1 . ARG A 1 694 ? 128.745 163.633 107.567 1.00 41.83  ? 694  ARG A NH1 1 
ATOM   4356  N NH2 . ARG A 1 694 ? 127.885 161.551 107.979 1.00 41.83  ? 694  ARG A NH2 1 
ATOM   4357  N N   . ASN A 1 695 ? 123.584 166.660 103.332 1.00 46.98  ? 695  ASN A N   1 
ATOM   4358  C CA  . ASN A 1 695 ? 123.049 166.394 102.002 1.00 46.98  ? 695  ASN A CA  1 
ATOM   4359  C C   . ASN A 1 695 ? 123.003 164.899 101.716 1.00 46.98  ? 695  ASN A C   1 
ATOM   4360  O O   . ASN A 1 695 ? 121.928 164.321 101.522 1.00 46.98  ? 695  ASN A O   1 
ATOM   4361  C CB  . ASN A 1 695 ? 123.900 167.099 100.944 1.00 46.98  ? 695  ASN A CB  1 
ATOM   4362  C CG  . ASN A 1 695 ? 123.728 168.597 100.961 1.00 46.98  ? 695  ASN A CG  1 
ATOM   4363  O OD1 . ASN A 1 695 ? 122.717 169.109 101.429 1.00 46.98  ? 695  ASN A OD1 1 
ATOM   4364  N ND2 . ASN A 1 695 ? 124.718 169.311 100.443 1.00 46.98  ? 695  ASN A ND2 1 
ATOM   4365  N N   . GLN A 1 696 ? 124.166 164.259 101.699 1.00 39.71  ? 696  GLN A N   1 
ATOM   4366  C CA  . GLN A 1 696 ? 124.299 162.871 101.285 1.00 39.71  ? 696  GLN A CA  1 
ATOM   4367  C C   . GLN A 1 696 ? 124.414 161.992 102.525 1.00 39.71  ? 696  GLN A C   1 
ATOM   4368  O O   . GLN A 1 696 ? 125.047 162.377 103.514 1.00 39.71  ? 696  GLN A O   1 
ATOM   4369  C CB  . GLN A 1 696 ? 125.503 162.689 100.356 1.00 39.71  ? 696  GLN A CB  1 
ATOM   4370  C CG  . GLN A 1 696 ? 126.881 162.962 100.965 1.00 39.71  ? 696  GLN A CG  1 
ATOM   4371  C CD  . GLN A 1 696 ? 127.237 164.434 101.031 1.00 39.71  ? 696  GLN A CD  1 
ATOM   4372  O OE1 . GLN A 1 696 ? 126.892 165.209 100.141 1.00 39.71  ? 696  GLN A OE1 1 
ATOM   4373  N NE2 . GLN A 1 696 ? 127.923 164.828 102.095 1.00 39.71  ? 696  GLN A NE2 1 
ATOM   4374  N N   . LEU A 1 697 ? 123.770 160.833 102.485 1.00 28.34  ? 697  LEU A N   1 
ATOM   4375  C CA  . LEU A 1 697 ? 123.791 159.895 103.594 1.00 28.34  ? 697  LEU A CA  1 
ATOM   4376  C C   . LEU A 1 697 ? 124.367 158.566 103.129 1.00 28.34  ? 697  LEU A C   1 
ATOM   4377  O O   . LEU A 1 697 ? 124.079 158.108 102.020 1.00 28.34  ? 697  LEU A O   1 
ATOM   4378  C CB  . LEU A 1 697 ? 122.385 159.695 104.163 1.00 28.34  ? 697  LEU A CB  1 
ATOM   4379  C CG  . LEU A 1 697 ? 121.677 160.931 104.724 1.00 28.34  ? 697  LEU A CG  1 
ATOM   4380  C CD1 . LEU A 1 697 ? 120.449 160.534 105.493 1.00 28.34  ? 697  LEU A CD1 1 
ATOM   4381  C CD2 . LEU A 1 697 ? 122.589 161.733 105.619 1.00 28.34  ? 697  LEU A CD2 1 
ATOM   4382  N N   . MET A 1 698 ? 125.188 157.951 103.982 1.00 27.93  ? 698  MET A N   1 
ATOM   4383  C CA  . MET A 1 698 ? 125.763 156.643 103.700 1.00 27.93  ? 698  MET A CA  1 
ATOM   4384  C C   . MET A 1 698 ? 124.964 155.509 104.324 1.00 27.93  ? 698  MET A C   1 
ATOM   4385  O O   . MET A 1 698 ? 125.516 154.440 104.605 1.00 27.93  ? 698  MET A O   1 
ATOM   4386  C CB  . MET A 1 698 ? 127.217 156.594 104.166 1.00 27.93  ? 698  MET A CB  1 
ATOM   4387  C CG  . MET A 1 698 ? 128.085 155.814 103.233 1.00 27.93  ? 698  MET A CG  1 
ATOM   4388  S SD  . MET A 1 698 ? 129.850 155.957 103.427 1.00 27.93  ? 698  MET A SD  1 
ATOM   4389  C CE  . MET A 1 698 ? 130.272 154.714 102.220 1.00 27.93  ? 698  MET A CE  1 
ATOM   4390  N N   . LEU A 1 699 ? 123.669 155.703 104.538 1.00 37.06  ? 699  LEU A N   1 
ATOM   4391  C CA  . LEU A 1 699 ? 122.865 154.709 105.227 1.00 37.06  ? 699  LEU A CA  1 
ATOM   4392  C C   . LEU A 1 699 ? 121.439 154.796 104.685 1.00 37.06  ? 699  LEU A C   1 
ATOM   4393  O O   . LEU A 1 699 ? 121.106 155.684 103.895 1.00 37.06  ? 699  LEU A O   1 
ATOM   4394  C CB  . LEU A 1 699 ? 123.011 154.920 106.747 1.00 37.06  ? 699  LEU A CB  1 
ATOM   4395  C CG  . LEU A 1 699 ? 122.411 154.066 107.876 1.00 37.06  ? 699  LEU A CG  1 
ATOM   4396  C CD1 . LEU A 1 699 ? 123.312 154.099 109.075 1.00 37.06  ? 699  LEU A CD1 1 
ATOM   4397  C CD2 . LEU A 1 699 ? 121.062 154.598 108.302 1.00 37.06  ? 699  LEU A CD2 1 
ATOM   4398  N N   . ARG A 1 700 ? 120.593 153.882 105.136 1.00 42.19  ? 700  ARG A N   1 
ATOM   4399  C CA  . ARG A 1 700 ? 119.199 153.686 104.790 1.00 42.19  ? 700  ARG A CA  1 
ATOM   4400  C C   . ARG A 1 700 ? 118.338 154.755 105.471 1.00 42.19  ? 700  ARG A C   1 
ATOM   4401  O O   . ARG A 1 700 ? 118.828 155.843 105.796 1.00 42.19  ? 700  ARG A O   1 
ATOM   4402  C CB  . ARG A 1 700 ? 118.791 152.259 105.172 1.00 42.19  ? 700  ARG A CB  1 
ATOM   4403  C CG  . ARG A 1 700 ? 119.489 151.181 104.353 1.00 42.19  ? 700  ARG A CG  1 
ATOM   4404  C CD  . ARG A 1 700 ? 119.863 149.972 105.206 1.00 42.19  ? 700  ARG A CD  1 
ATOM   4405  N NE  . ARG A 1 700 ? 121.094 150.188 105.964 1.00 42.19  ? 700  ARG A NE  1 
ATOM   4406  C CZ  . ARG A 1 700 ? 122.310 149.875 105.526 1.00 42.19  ? 700  ARG A CZ  1 
ATOM   4407  N NH1 . ARG A 1 700 ? 123.370 150.110 106.287 1.00 42.19  ? 700  ARG A NH1 1 
ATOM   4408  N NH2 . ARG A 1 700 ? 122.465 149.327 104.328 1.00 42.19  ? 700  ARG A NH2 1 
ATOM   4409  N N   . GLN A 1 701 ? 117.043 154.450 105.649 1.00 48.37  ? 701  GLN A N   1 
ATOM   4410  C CA  . GLN A 1 701 ? 115.914 155.329 105.972 1.00 48.37  ? 701  GLN A CA  1 
ATOM   4411  C C   . GLN A 1 701 ? 116.190 156.484 106.929 1.00 48.37  ? 701  GLN A C   1 
ATOM   4412  O O   . GLN A 1 701 ? 116.950 156.353 107.894 1.00 48.37  ? 701  GLN A O   1 
ATOM   4413  C CB  . GLN A 1 701 ? 114.762 154.487 106.546 1.00 48.37  ? 701  GLN A CB  1 
ATOM   4414  C CG  . GLN A 1 701 ? 115.073 153.764 107.865 1.00 48.37  ? 701  GLN A CG  1 
ATOM   4415  C CD  . GLN A 1 701 ? 113.883 153.012 108.434 1.00 48.37  ? 701  GLN A CD  1 
ATOM   4416  O OE1 . GLN A 1 701 ? 112.788 153.043 107.873 1.00 48.37  ? 701  GLN A OE1 1 
ATOM   4417  N NE2 . GLN A 1 701 ? 114.090 152.343 109.563 1.00 48.37  ? 701  GLN A NE2 1 
ATOM   4418  N N   . LYS A 1 702 ? 115.599 157.640 106.639 1.00 46.30  ? 702  LYS A N   1 
ATOM   4419  C CA  . LYS A 1 702 ? 115.893 158.870 107.365 1.00 46.30  ? 702  LYS A CA  1 
ATOM   4420  C C   . LYS A 1 702 ? 115.123 158.946 108.676 1.00 46.30  ? 702  LYS A C   1 
ATOM   4421  O O   . LYS A 1 702 ? 114.468 159.954 108.955 1.00 46.30  ? 702  LYS A O   1 
ATOM   4422  C CB  . LYS A 1 702 ? 115.548 160.084 106.499 1.00 46.30  ? 702  LYS A CB  1 
ATOM   4423  C CG  . LYS A 1 702 ? 116.688 160.620 105.647 1.00 46.30  ? 702  LYS A CG  1 
ATOM   4424  C CD  . LYS A 1 702 ? 117.008 159.717 104.460 1.00 46.30  ? 702  LYS A CD  1 
ATOM   4425  C CE  . LYS A 1 702 ? 115.788 159.405 103.622 1.00 46.30  ? 702  LYS A CE  1 
ATOM   4426  N NZ  . LYS A 1 702 ? 116.166 158.586 102.441 1.00 46.30  ? 702  LYS A NZ  1 
ATOM   4427  N N   . SER A 1 703 ? 115.205 157.909 109.483 1.00 42.52  ? 703  SER A N   1 
ATOM   4428  C CA  . SER A 1 703 ? 114.523 157.817 110.765 1.00 42.52  ? 703  SER A CA  1 
ATOM   4429  C C   . SER A 1 703 ? 115.466 157.435 111.888 1.00 42.52  ? 703  SER A C   1 
ATOM   4430  O O   . SER A 1 703 ? 115.322 157.943 113.001 1.00 42.52  ? 703  SER A O   1 
ATOM   4431  C CB  . SER A 1 703 ? 113.377 156.799 110.687 1.00 42.52  ? 703  SER A CB  1 
ATOM   4432  O OG  . SER A 1 703 ? 113.048 156.309 111.975 1.00 42.52  ? 703  SER A OG  1 
ATOM   4433  N N   . ILE A 1 704 ? 116.432 156.552 111.622 1.00 41.72  ? 704  ILE A N   1 
ATOM   4434  C CA  . ILE A 1 704 ? 117.407 156.175 112.641 1.00 41.72  ? 704  ILE A CA  1 
ATOM   4435  C C   . ILE A 1 704 ? 118.582 157.129 112.692 1.00 41.72  ? 704  ILE A C   1 
ATOM   4436  O O   . ILE A 1 704 ? 119.437 156.994 113.573 1.00 41.72  ? 704  ILE A O   1 
ATOM   4437  C CB  . ILE A 1 704 ? 117.897 154.735 112.413 1.00 41.72  ? 704  ILE A CB  1 
ATOM   4438  C CG1 . ILE A 1 704 ? 118.297 154.529 110.953 1.00 41.72  ? 704  ILE A CG1 1 
ATOM   4439  C CG2 . ILE A 1 704 ? 116.819 153.743 112.835 1.00 41.72  ? 704  ILE A CG2 1 
ATOM   4440  C CD1 . ILE A 1 704 ? 118.577 153.081 110.591 1.00 41.72  ? 704  ILE A CD1 1 
ATOM   4441  N N   . TYR A 1 705 ? 118.650 158.090 111.773 1.00 37.61  ? 705  TYR A N   1 
ATOM   4442  C CA  . TYR A 1 705 ? 119.640 159.149 111.900 1.00 37.61  ? 705  TYR A CA  1 
ATOM   4443  C C   . TYR A 1 705 ? 119.295 160.076 113.051 1.00 37.61  ? 705  TYR A C   1 
ATOM   4444  O O   . TYR A 1 705 ? 120.176 160.487 113.809 1.00 37.61  ? 705  TYR A O   1 
ATOM   4445  C CB  . TYR A 1 705 ? 119.735 159.935 110.600 1.00 37.61  ? 705  TYR A CB  1 
ATOM   4446  C CG  . TYR A 1 705 ? 120.853 159.479 109.713 1.00 37.61  ? 705  TYR A CG  1 
ATOM   4447  C CD1 . TYR A 1 705 ? 122.134 159.977 109.876 1.00 37.61  ? 705  TYR A CD1 1 
ATOM   4448  C CD2 . TYR A 1 705 ? 120.631 158.546 108.715 1.00 37.61  ? 705  TYR A CD2 1 
ATOM   4449  C CE1 . TYR A 1 705 ? 123.167 159.560 109.063 1.00 37.61  ? 705  TYR A CE1 1 
ATOM   4450  C CE2 . TYR A 1 705 ? 121.654 158.123 107.900 1.00 37.61  ? 705  TYR A CE2 1 
ATOM   4451  C CZ  . TYR A 1 705 ? 122.919 158.630 108.079 1.00 37.61  ? 705  TYR A CZ  1 
ATOM   4452  O OH  . TYR A 1 705 ? 123.941 158.206 107.268 1.00 37.61  ? 705  TYR A OH  1 
ATOM   4453  N N   . TYR A 1 706 ? 118.016 160.407 113.200 1.00 46.22  ? 706  TYR A N   1 
ATOM   4454  C CA  . TYR A 1 706 ? 117.563 161.304 114.249 1.00 46.22  ? 706  TYR A CA  1 
ATOM   4455  C C   . TYR A 1 706 ? 117.503 160.639 115.611 1.00 46.22  ? 706  TYR A C   1 
ATOM   4456  O O   . TYR A 1 706 ? 117.579 161.335 116.629 1.00 46.22  ? 706  TYR A O   1 
ATOM   4457  C CB  . TYR A 1 706 ? 116.178 161.856 113.908 1.00 46.22  ? 706  TYR A CB  1 
ATOM   4458  C CG  . TYR A 1 706 ? 116.115 162.626 112.611 1.00 46.22  ? 706  TYR A CG  1 
ATOM   4459  C CD1 . TYR A 1 706 ? 116.541 163.943 112.545 1.00 46.22  ? 706  TYR A CD1 1 
ATOM   4460  C CD2 . TYR A 1 706 ? 115.635 162.032 111.451 1.00 46.22  ? 706  TYR A CD2 1 
ATOM   4461  C CE1 . TYR A 1 706 ? 116.487 164.648 111.364 1.00 46.22  ? 706  TYR A CE1 1 
ATOM   4462  C CE2 . TYR A 1 706 ? 115.579 162.730 110.263 1.00 46.22  ? 706  TYR A CE2 1 
ATOM   4463  C CZ  . TYR A 1 706 ? 116.004 164.037 110.225 1.00 46.22  ? 706  TYR A CZ  1 
ATOM   4464  O OH  . TYR A 1 706 ? 115.948 164.739 109.043 1.00 46.22  ? 706  TYR A OH  1 
ATOM   4465  N N   . PHE A 1 707 ? 117.348 159.315 115.654 1.00 42.20  ? 707  PHE A N   1 
ATOM   4466  C CA  . PHE A 1 707 ? 117.357 158.603 116.925 1.00 42.20  ? 707  PHE A CA  1 
ATOM   4467  C C   . PHE A 1 707 ? 118.751 158.593 117.536 1.00 42.20  ? 707  PHE A C   1 
ATOM   4468  O O   . PHE A 1 707 ? 118.898 158.595 118.761 1.00 42.20  ? 707  PHE A O   1 
ATOM   4469  C CB  . PHE A 1 707 ? 116.843 157.177 116.731 1.00 42.20  ? 707  PHE A CB  1 
ATOM   4470  C CG  . PHE A 1 707 ? 116.817 156.370 117.990 1.00 42.20  ? 707  PHE A CG  1 
ATOM   4471  C CD1 . PHE A 1 707 ? 117.468 155.151 118.060 1.00 42.20  ? 707  PHE A CD1 1 
ATOM   4472  C CD2 . PHE A 1 707 ? 116.149 156.834 119.109 1.00 42.20  ? 707  PHE A CD2 1 
ATOM   4473  C CE1 . PHE A 1 707 ? 117.450 154.405 119.223 1.00 42.20  ? 707  PHE A CE1 1 
ATOM   4474  C CE2 . PHE A 1 707 ? 116.126 156.094 120.277 1.00 42.20  ? 707  PHE A CE2 1 
ATOM   4475  C CZ  . PHE A 1 707 ? 116.778 154.878 120.332 1.00 42.20  ? 707  PHE A CZ  1 
ATOM   4476  N N   . SER A 1 708 ? 119.785 158.603 116.699 1.00 32.94  ? 708  SER A N   1 
ATOM   4477  C CA  . SER A 1 708 ? 121.139 158.684 117.220 1.00 32.94  ? 708  SER A CA  1 
ATOM   4478  C C   . SER A 1 708 ? 121.537 160.107 117.575 1.00 32.94  ? 708  SER A C   1 
ATOM   4479  O O   . SER A 1 708 ? 122.602 160.305 118.159 1.00 32.94  ? 708  SER A O   1 
ATOM   4480  C CB  . SER A 1 708 ? 122.127 158.105 116.214 1.00 32.94  ? 708  SER A CB  1 
ATOM   4481  O OG  . SER A 1 708 ? 123.435 158.559 116.487 1.00 32.94  ? 708  SER A OG  1 
ATOM   4482  N N   . MET A 1 709 ? 120.718 161.101 117.240 1.00 35.92  ? 709  MET A N   1 
ATOM   4483  C CA  . MET A 1 709 ? 121.012 162.474 117.626 1.00 35.92  ? 709  MET A CA  1 
ATOM   4484  C C   . MET A 1 709 ? 120.451 162.841 118.989 1.00 35.92  ? 709  MET A C   1 
ATOM   4485  O O   . MET A 1 709 ? 120.892 163.833 119.574 1.00 35.92  ? 709  MET A O   1 
ATOM   4486  C CB  . MET A 1 709 ? 120.474 163.446 116.578 1.00 35.92  ? 709  MET A CB  1 
ATOM   4487  C CG  . MET A 1 709 ? 121.097 163.261 115.219 1.00 35.92  ? 709  MET A CG  1 
ATOM   4488  S SD  . MET A 1 709 ? 120.602 164.499 114.020 1.00 35.92  ? 709  MET A SD  1 
ATOM   4489  C CE  . MET A 1 709 ? 121.913 165.694 114.217 1.00 35.92  ? 709  MET A CE  1 
ATOM   4490  N N   . VAL A 1 710 ? 119.493 162.077 119.504 1.00 33.27  ? 710  VAL A N   1 
ATOM   4491  C CA  . VAL A 1 710 ? 118.928 162.349 120.818 1.00 33.27  ? 710  VAL A CA  1 
ATOM   4492  C C   . VAL A 1 710 ? 119.671 161.481 121.828 1.00 33.27  ? 710  VAL A C   1 
ATOM   4493  O O   . VAL A 1 710 ? 119.705 161.784 123.025 1.00 33.27  ? 710  VAL A O   1 
ATOM   4494  C CB  . VAL A 1 710 ? 117.400 162.111 120.823 1.00 33.27  ? 710  VAL A CB  1 
ATOM   4495  C CG1 . VAL A 1 710 ? 117.055 160.650 120.593 1.00 33.27  ? 710  VAL A CG1 1 
ATOM   4496  C CG2 . VAL A 1 710 ? 116.736 162.662 122.086 1.00 33.27  ? 710  VAL A CG2 1 
ATOM   4497  N N   . LEU A 1 711 ? 120.324 160.423 121.343 1.00 29.59  ? 711  LEU A N   1 
ATOM   4498  C CA  . LEU A 1 711 ? 121.098 159.556 122.219 1.00 29.59  ? 711  LEU A CA  1 
ATOM   4499  C C   . LEU A 1 711 ? 122.505 160.060 122.488 1.00 29.59  ? 711  LEU A C   1 
ATOM   4500  O O   . LEU A 1 711 ? 123.221 159.431 123.268 1.00 29.59  ? 711  LEU A O   1 
ATOM   4501  C CB  . LEU A 1 711 ? 121.189 158.146 121.652 1.00 29.59  ? 711  LEU A CB  1 
ATOM   4502  C CG  . LEU A 1 711 ? 119.947 157.279 121.754 1.00 29.59  ? 711  LEU A CG  1 
ATOM   4503  C CD1 . LEU A 1 711 ? 120.211 155.960 121.064 1.00 29.59  ? 711  LEU A CD1 1 
ATOM   4504  C CD2 . LEU A 1 711 ? 119.603 157.065 123.213 1.00 29.59  ? 711  LEU A CD2 1 
ATOM   4505  N N   . ASN A 1 712 ? 122.941 161.133 121.854 1.00 20.62  ? 712  ASN A N   1 
ATOM   4506  C CA  . ASN A 1 712 ? 124.180 161.758 122.278 1.00 20.62  ? 712  ASN A CA  1 
ATOM   4507  C C   . ASN A 1 712 ? 123.945 162.885 123.270 1.00 20.62  ? 712  ASN A C   1 
ATOM   4508  O O   . ASN A 1 712 ? 124.911 163.500 123.732 1.00 20.62  ? 712  ASN A O   1 
ATOM   4509  C CB  . ASN A 1 712 ? 124.951 162.284 121.077 1.00 20.62  ? 712  ASN A CB  1 
ATOM   4510  C CG  . ASN A 1 712 ? 126.433 162.217 121.282 1.00 20.62  ? 712  ASN A CG  1 
ATOM   4511  O OD1 . ASN A 1 712 ? 126.984 161.150 121.519 1.00 20.62  ? 712  ASN A OD1 1 
ATOM   4512  N ND2 . ASN A 1 712 ? 127.090 163.362 121.219 1.00 20.62  ? 712  ASN A ND2 1 
ATOM   4513  N N   . LEU A 1 713 ? 122.685 163.161 123.611 1.00 31.04  ? 713  LEU A N   1 
ATOM   4514  C CA  . LEU A 1 713 ? 122.334 164.180 124.588 1.00 31.04  ? 713  LEU A CA  1 
ATOM   4515  C C   . LEU A 1 713 ? 121.723 163.593 125.848 1.00 31.04  ? 713  LEU A C   1 
ATOM   4516  O O   . LEU A 1 713 ? 122.000 164.095 126.941 1.00 31.04  ? 713  LEU A O   1 
ATOM   4517  C CB  . LEU A 1 713 ? 121.353 165.185 123.965 1.00 31.04  ? 713  LEU A CB  1 
ATOM   4518  C CG  . LEU A 1 713 ? 121.297 166.654 124.402 1.00 31.04  ? 713  LEU A CG  1 
ATOM   4519  C CD1 . LEU A 1 713 ? 120.488 167.425 123.378 1.00 31.04  ? 713  LEU A CD1 1 
ATOM   4520  C CD2 . LEU A 1 713 ? 120.712 166.895 125.791 1.00 31.04  ? 713  LEU A CD2 1 
ATOM   4521  N N   . VAL A 1 714 ? 120.887 162.570 125.716 1.00 28.86  ? 714  VAL A N   1 
ATOM   4522  C CA  . VAL A 1 714 ? 120.464 161.764 126.850 1.00 28.86  ? 714  VAL A CA  1 
ATOM   4523  C C   . VAL A 1 714 ? 121.657 161.112 127.523 1.00 28.86  ? 714  VAL A C   1 
ATOM   4524  O O   . VAL A 1 714 ? 121.796 161.164 128.745 1.00 28.86  ? 714  VAL A O   1 
ATOM   4525  C CB  . VAL A 1 714 ? 119.432 160.712 126.386 1.00 28.86  ? 714  VAL A CB  1 
ATOM   4526  C CG1 . VAL A 1 714 ? 119.129 159.726 127.492 1.00 28.86  ? 714  VAL A CG1 1 
ATOM   4527  C CG2 . VAL A 1 714 ? 118.158 161.388 125.926 1.00 28.86  ? 714  VAL A CG2 1 
ATOM   4528  N N   . LEU A 1 715 ? 122.556 160.527 126.727 1.00 22.76  ? 715  LEU A N   1 
ATOM   4529  C CA  . LEU A 1 715 ? 123.700 159.808 127.268 1.00 22.76  ? 715  LEU A CA  1 
ATOM   4530  C C   . LEU A 1 715 ? 124.883 160.706 127.574 1.00 22.76  ? 715  LEU A C   1 
ATOM   4531  O O   . LEU A 1 715 ? 125.958 160.188 127.881 1.00 22.76  ? 715  LEU A O   1 
ATOM   4532  C CB  . LEU A 1 715 ? 124.149 158.706 126.312 1.00 22.76  ? 715  LEU A CB  1 
ATOM   4533  C CG  . LEU A 1 715 ? 123.279 157.455 126.245 1.00 22.76  ? 715  LEU A CG  1 
ATOM   4534  C CD1 . LEU A 1 715 ? 123.640 156.593 125.051 1.00 22.76  ? 715  LEU A CD1 1 
ATOM   4535  C CD2 . LEU A 1 715 ? 123.424 156.671 127.521 1.00 22.76  ? 715  LEU A CD2 1 
ATOM   4536  N N   . ARG A 1 716 ? 124.743 162.023 127.486 1.00 20.43  ? 716  ARG A N   1 
ATOM   4537  C CA  . ARG A 1 716 ? 125.805 162.832 128.058 1.00 20.43  ? 716  ARG A CA  1 
ATOM   4538  C C   . ARG A 1 716 ? 125.378 163.453 129.392 1.00 20.43  ? 716  ARG A C   1 
ATOM   4539  O O   . ARG A 1 716 ? 125.977 164.431 129.849 1.00 20.43  ? 716  ARG A O   1 
ATOM   4540  C CB  . ARG A 1 716 ? 126.286 163.864 127.035 1.00 20.43  ? 716  ARG A CB  1 
ATOM   4541  C CG  . ARG A 1 716 ? 127.748 164.224 127.261 1.00 20.43  ? 716  ARG A CG  1 
ATOM   4542  C CD  . ARG A 1 716 ? 128.324 165.233 126.323 1.00 20.43  ? 716  ARG A CD  1 
ATOM   4543  N NE  . ARG A 1 716 ? 128.556 164.731 124.981 1.00 20.43  ? 716  ARG A NE  1 
ATOM   4544  C CZ  . ARG A 1 716 ? 129.702 164.198 124.590 1.00 20.43  ? 716  ARG A CZ  1 
ATOM   4545  N NH1 . ARG A 1 716 ? 130.714 164.109 125.433 1.00 20.43  ? 716  ARG A NH1 1 
ATOM   4546  N NH2 . ARG A 1 716 ? 129.845 163.776 123.351 1.00 20.43  ? 716  ARG A NH2 1 
ATOM   4547  N N   . LEU A 1 717 ? 124.319 162.927 130.007 1.00 27.82  ? 717  LEU A N   1 
ATOM   4548  C CA  . LEU A 1 717 ? 124.113 163.057 131.442 1.00 27.82  ? 717  LEU A CA  1 
ATOM   4549  C C   . LEU A 1 717 ? 124.781 161.930 132.205 1.00 27.82  ? 717  LEU A C   1 
ATOM   4550  O O   . LEU A 1 717 ? 125.044 162.079 133.402 1.00 27.82  ? 717  LEU A O   1 
ATOM   4551  C CB  . LEU A 1 717 ? 122.621 163.074 131.783 1.00 27.82  ? 717  LEU A CB  1 
ATOM   4552  C CG  . LEU A 1 717 ? 121.868 164.404 131.756 1.00 27.82  ? 717  LEU A CG  1 
ATOM   4553  C CD1 . LEU A 1 717 ? 120.366 164.159 131.684 1.00 27.82  ? 717  LEU A CD1 1 
ATOM   4554  C CD2 . LEU A 1 717 ? 122.225 165.242 132.978 1.00 27.82  ? 717  LEU A CD2 1 
ATOM   4555  N N   . ALA A 1 718 ? 125.074 160.817 131.530 1.00 26.98  ? 718  ALA A N   1 
ATOM   4556  C CA  . ALA A 1 718 ? 125.944 159.804 132.107 1.00 26.98  ? 718  ALA A CA  1 
ATOM   4557  C C   . ALA A 1 718 ? 127.374 160.319 132.213 1.00 26.98  ? 718  ALA A C   1 
ATOM   4558  O O   . ALA A 1 718 ? 127.993 160.240 133.279 1.00 26.98  ? 718  ALA A O   1 
ATOM   4559  C CB  . ALA A 1 718 ? 125.881 158.535 131.267 1.00 26.98  ? 718  ALA A CB  1 
ATOM   4560  N N   . TRP A 1 719 ? 127.909 160.856 131.119 1.00 25.06  ? 719  TRP A N   1 
ATOM   4561  C CA  . TRP A 1 719 ? 129.036 161.775 131.183 1.00 25.06  ? 719  TRP A CA  1 
ATOM   4562  C C   . TRP A 1 719 ? 128.623 163.007 131.987 1.00 25.06  ? 719  TRP A C   1 
ATOM   4563  O O   . TRP A 1 719 ? 127.444 163.360 132.039 1.00 25.06  ? 719  TRP A O   1 
ATOM   4564  C CB  . TRP A 1 719 ? 129.466 162.167 129.770 1.00 25.06  ? 719  TRP A CB  1 
ATOM   4565  C CG  . TRP A 1 719 ? 130.811 162.791 129.637 1.00 25.06  ? 719  TRP A CG  1 
ATOM   4566  C CD1 . TRP A 1 719 ? 132.012 162.152 129.611 1.00 25.06  ? 719  TRP A CD1 1 
ATOM   4567  C CD2 . TRP A 1 719 ? 131.096 164.181 129.479 1.00 25.06  ? 719  TRP A CD2 1 
ATOM   4568  N NE1 . TRP A 1 719 ? 133.029 163.058 129.451 1.00 25.06  ? 719  TRP A NE1 1 
ATOM   4569  C CE2 . TRP A 1 719 ? 132.490 164.313 129.375 1.00 25.06  ? 719  TRP A CE2 1 
ATOM   4570  C CE3 . TRP A 1 719 ? 130.308 165.329 129.429 1.00 25.06  ? 719  TRP A CE3 1 
ATOM   4571  C CZ2 . TRP A 1 719 ? 133.107 165.544 129.224 1.00 25.06  ? 719  TRP A CZ2 1 
ATOM   4572  C CZ3 . TRP A 1 719 ? 130.923 166.543 129.274 1.00 25.06  ? 719  TRP A CZ3 1 
ATOM   4573  C CH2 . TRP A 1 719 ? 132.305 166.645 129.175 1.00 25.06  ? 719  TRP A CH2 1 
ATOM   4574  N N   . LEU A 1 720 ? 129.603 163.616 132.671 1.00 27.53  ? 720  LEU A N   1 
ATOM   4575  C CA  . LEU A 1 720 ? 129.469 164.679 133.682 1.00 27.53  ? 720  LEU A CA  1 
ATOM   4576  C C   . LEU A 1 720 ? 128.801 164.182 134.966 1.00 27.53  ? 720  LEU A C   1 
ATOM   4577  O O   . LEU A 1 720 ? 128.690 164.922 135.946 1.00 27.53  ? 720  LEU A O   1 
ATOM   4578  C CB  . LEU A 1 720 ? 128.740 165.922 133.137 1.00 27.53  ? 720  LEU A CB  1 
ATOM   4579  C CG  . LEU A 1 720 ? 128.891 167.293 133.793 1.00 27.53  ? 720  LEU A CG  1 
ATOM   4580  C CD1 . LEU A 1 720 ? 130.171 167.968 133.348 1.00 27.53  ? 720  LEU A CD1 1 
ATOM   4581  C CD2 . LEU A 1 720 ? 127.670 168.135 133.494 1.00 27.53  ? 720  LEU A CD2 1 
ATOM   4582  N N   . GLN A 1 721 ? 128.384 162.927 135.012 1.00 29.35  ? 721  GLN A N   1 
ATOM   4583  C CA  . GLN A 1 721 ? 128.070 162.356 136.304 1.00 29.35  ? 721  GLN A CA  1 
ATOM   4584  C C   . GLN A 1 721 ? 129.240 161.474 136.674 1.00 29.35  ? 721  GLN A C   1 
ATOM   4585  O O   . GLN A 1 721 ? 129.649 161.423 137.834 1.00 29.35  ? 721  GLN A O   1 
ATOM   4586  C CB  . GLN A 1 721 ? 126.759 161.570 136.272 1.00 29.35  ? 721  GLN A CB  1 
ATOM   4587  C CG  . GLN A 1 721 ? 126.529 160.601 137.445 1.00 29.35  ? 721  GLN A CG  1 
ATOM   4588  C CD  . GLN A 1 721 ? 126.662 161.209 138.846 1.00 29.35  ? 721  GLN A CD  1 
ATOM   4589  O OE1 . GLN A 1 721 ? 126.427 162.400 139.066 1.00 29.35  ? 721  GLN A OE1 1 
ATOM   4590  N NE2 . GLN A 1 721 ? 127.047 160.375 139.804 1.00 29.35  ? 721  GLN A NE2 1 
ATOM   4591  N N   . THR A 1 722 ? 129.851 160.849 135.677 1.00 29.73  ? 722  THR A N   1 
ATOM   4592  C CA  . THR A 1 722 ? 130.894 159.883 135.970 1.00 29.73  ? 722  THR A CA  1 
ATOM   4593  C C   . THR A 1 722 ? 132.252 160.564 136.037 1.00 29.73  ? 722  THR A C   1 
ATOM   4594  O O   . THR A 1 722 ? 133.239 159.940 136.429 1.00 29.73  ? 722  THR A O   1 
ATOM   4595  C CB  . THR A 1 722 ? 130.890 158.764 134.931 1.00 29.73  ? 722  THR A CB  1 
ATOM   4596  O OG1 . THR A 1 722 ? 130.952 159.320 133.615 1.00 29.73  ? 722  THR A OG1 1 
ATOM   4597  C CG2 . THR A 1 722 ? 129.627 157.952 135.057 1.00 29.73  ? 722  THR A CG2 1 
ATOM   4598  N N   . VAL A 1 723 ? 132.318 161.841 135.676 1.00 29.86  ? 723  VAL A N   1 
ATOM   4599  C CA  . VAL A 1 723 ? 133.563 162.586 135.741 1.00 29.86  ? 723  VAL A CA  1 
ATOM   4600  C C   . VAL A 1 723 ? 133.481 163.740 136.743 1.00 29.86  ? 723  VAL A C   1 
ATOM   4601  O O   . VAL A 1 723 ? 134.385 164.569 136.804 1.00 29.86  ? 723  VAL A O   1 
ATOM   4602  C CB  . VAL A 1 723 ? 134.004 163.079 134.357 1.00 29.86  ? 723  VAL A CB  1 
ATOM   4603  C CG1 . VAL A 1 723 ? 134.156 161.919 133.403 1.00 29.86  ? 723  VAL A CG1 1 
ATOM   4604  C CG2 . VAL A 1 723 ? 133.078 164.138 133.821 1.00 29.86  ? 723  VAL A CG2 1 
ATOM   4605  N N   . LEU A 1 724 ? 132.407 163.811 137.529 1.00 36.80  ? 724  LEU A N   1 
ATOM   4606  C CA  . LEU A 1 724 ? 132.395 164.685 138.695 1.00 36.80  ? 724  LEU A CA  1 
ATOM   4607  C C   . LEU A 1 724 ? 132.181 163.905 139.981 1.00 36.80  ? 724  LEU A C   1 
ATOM   4608  O O   . LEU A 1 724 ? 132.293 164.487 141.065 1.00 36.80  ? 724  LEU A O   1 
ATOM   4609  C CB  . LEU A 1 724 ? 131.322 165.769 138.592 1.00 36.80  ? 724  LEU A CB  1 
ATOM   4610  C CG  . LEU A 1 724 ? 131.223 166.654 137.354 1.00 36.80  ? 724  LEU A CG  1 
ATOM   4611  C CD1 . LEU A 1 724 ? 129.983 167.524 137.447 1.00 36.80  ? 724  LEU A CD1 1 
ATOM   4612  C CD2 . LEU A 1 724 ? 132.461 167.505 137.206 1.00 36.80  ? 724  LEU A CD2 1 
ATOM   4613  N N   . HIS A 1 725 ? 131.881 162.617 139.891 1.00 43.59  ? 725  HIS A N   1 
ATOM   4614  C CA  . HIS A 1 725 ? 131.521 161.766 141.018 1.00 43.59  ? 725  HIS A CA  1 
ATOM   4615  C C   . HIS A 1 725 ? 132.387 160.528 141.023 1.00 43.59  ? 725  HIS A C   1 
ATOM   4616  O O   . HIS A 1 725 ? 131.887 159.407 140.903 1.00 43.59  ? 725  HIS A O   1 
ATOM   4617  C CB  . HIS A 1 725 ? 130.052 161.355 141.022 1.00 43.59  ? 725  HIS A CB  1 
ATOM   4618  C CG  . HIS A 1 725 ? 129.142 162.353 141.667 1.00 43.59  ? 725  HIS A CG  1 
ATOM   4619  N ND1 . HIS A 1 725 ? 128.393 163.254 140.943 1.00 43.59  ? 725  HIS A ND1 1 
ATOM   4620  C CD2 . HIS A 1 725 ? 128.871 162.600 142.970 1.00 43.59  ? 725  HIS A CD2 1 
ATOM   4621  C CE1 . HIS A 1 725 ? 127.693 164.008 141.771 1.00 43.59  ? 725  HIS A CE1 1 
ATOM   4622  N NE2 . HIS A 1 725 ? 127.966 163.632 143.008 1.00 43.59  ? 725  HIS A NE2 1 
ATOM   4623  N N   . SER A 1 726 ? 133.709 160.746 141.047 1.00 45.85  ? 726  SER A N   1 
ATOM   4624  C CA  . SER A 1 726 ? 134.738 159.707 141.095 1.00 45.85  ? 726  SER A CA  1 
ATOM   4625  C C   . SER A 1 726 ? 134.451 158.642 142.142 1.00 45.85  ? 726  SER A C   1 
ATOM   4626  O O   . SER A 1 726 ? 134.425 158.928 143.343 1.00 45.85  ? 726  SER A O   1 
ATOM   4627  C CB  . SER A 1 726 ? 136.105 160.330 141.369 1.00 45.85  ? 726  SER A CB  1 
ATOM   4628  O OG  . SER A 1 726 ? 136.990 159.375 141.927 1.00 45.85  ? 726  SER A OG  1 
ATOM   4629  N N   . SER A 1 727 ? 134.244 157.410 141.674 1.00 49.91  ? 727  SER A N   1 
ATOM   4630  C CA  . SER A 1 727 ? 133.525 156.419 142.462 1.00 49.91  ? 727  SER A CA  1 
ATOM   4631  C C   . SER A 1 727 ? 134.368 155.887 143.610 1.00 49.91  ? 727  SER A C   1 
ATOM   4632  O O   . SER A 1 727 ? 133.886 155.807 144.746 1.00 49.91  ? 727  SER A O   1 
ATOM   4633  C CB  . SER A 1 727 ? 133.060 155.277 141.567 1.00 49.91  ? 727  SER A CB  1 
ATOM   4634  O OG  . SER A 1 727 ? 132.585 154.200 142.348 1.00 49.91  ? 727  SER A OG  1 
ATOM   4635  N N   . PHE A 1 728 ? 135.621 155.517 143.350 1.00 48.48  ? 728  PHE A N   1 
ATOM   4636  C CA  . PHE A 1 728 ? 136.437 155.092 144.478 1.00 48.48  ? 728  PHE A CA  1 
ATOM   4637  C C   . PHE A 1 728 ? 137.279 156.240 145.016 1.00 48.48  ? 728  PHE A C   1 
ATOM   4638  O O   . PHE A 1 728 ? 138.512 156.175 145.020 1.00 48.48  ? 728  PHE A O   1 
ATOM   4639  C CB  . PHE A 1 728 ? 137.332 153.905 144.132 1.00 48.48  ? 728  PHE A CB  1 
ATOM   4640  C CG  . PHE A 1 728 ? 137.589 153.020 145.314 1.00 48.48  ? 728  PHE A CG  1 
ATOM   4641  C CD1 . PHE A 1 728 ? 136.662 152.056 145.683 1.00 48.48  ? 728  PHE A CD1 1 
ATOM   4642  C CD2 . PHE A 1 728 ? 138.705 153.208 146.112 1.00 48.48  ? 728  PHE A CD2 1 
ATOM   4643  C CE1 . PHE A 1 728 ? 136.876 151.262 146.789 1.00 48.48  ? 728  PHE A CE1 1 
ATOM   4644  C CE2 . PHE A 1 728 ? 138.916 152.423 147.221 1.00 48.48  ? 728  PHE A CE2 1 
ATOM   4645  C CZ  . PHE A 1 728 ? 138.006 151.447 147.557 1.00 48.48  ? 728  PHE A CZ  1 
ATOM   4646  N N   . GLU A 1 729 ? 136.615 157.312 145.436 1.00 55.60  ? 729  GLU A N   1 
ATOM   4647  C CA  . GLU A 1 729 ? 137.249 158.338 146.248 1.00 55.60  ? 729  GLU A CA  1 
ATOM   4648  C C   . GLU A 1 729 ? 136.276 158.732 147.354 1.00 55.60  ? 729  GLU A C   1 
ATOM   4649  O O   . GLU A 1 729 ? 136.681 159.132 148.450 1.00 55.60  ? 729  GLU A O   1 
ATOM   4650  C CB  . GLU A 1 729 ? 137.651 159.533 145.376 1.00 55.60  ? 729  GLU A CB  1 
ATOM   4651  C CG  . GLU A 1 729 ? 138.300 160.693 146.115 1.00 55.60  ? 729  GLU A CG  1 
ATOM   4652  C CD  . GLU A 1 729 ? 138.121 162.012 145.394 1.00 55.60  ? 729  GLU A CD  1 
ATOM   4653  O OE1 . GLU A 1 729 ? 137.114 162.704 145.658 1.00 55.60  ? 729  GLU A OE1 1 
ATOM   4654  O OE2 . GLU A 1 729 ? 138.987 162.359 144.565 1.00 55.60  ? 729  GLU A OE2 1 
ATOM   4655  N N   . HIS A 1 730 ? 134.986 158.572 147.082 1.00 56.49  ? 730  HIS A N   1 
ATOM   4656  C CA  . HIS A 1 730 ? 133.918 159.055 147.950 1.00 56.49  ? 730  HIS A CA  1 
ATOM   4657  C C   . HIS A 1 730 ? 132.730 158.107 147.809 1.00 56.49  ? 730  HIS A C   1 
ATOM   4658  O O   . HIS A 1 730 ? 132.903 156.933 147.464 1.00 56.49  ? 730  HIS A O   1 
ATOM   4659  C CB  . HIS A 1 730 ? 133.576 160.523 147.666 1.00 56.49  ? 730  HIS A CB  1 
ATOM   4660  C CG  . HIS A 1 730 ? 133.307 160.830 146.227 1.00 56.49  ? 730  HIS A CG  1 
ATOM   4661  N ND1 . HIS A 1 730 ? 134.080 161.711 145.501 1.00 56.49  ? 730  HIS A ND1 1 
ATOM   4662  C CD2 . HIS A 1 730 ? 132.334 160.404 145.389 1.00 56.49  ? 730  HIS A CD2 1 
ATOM   4663  C CE1 . HIS A 1 730 ? 133.605 161.802 144.273 1.00 56.49  ? 730  HIS A CE1 1 
ATOM   4664  N NE2 . HIS A 1 730 ? 132.546 161.018 144.179 1.00 56.49  ? 730  HIS A NE2 1 
ATOM   4665  N N   . VAL A 1 731 ? 131.524 158.646 148.046 1.00 52.21  ? 731  VAL A N   1 
ATOM   4666  C CA  . VAL A 1 731 ? 130.298 158.022 148.561 1.00 52.21  ? 731  VAL A CA  1 
ATOM   4667  C C   . VAL A 1 731 ? 130.013 156.600 148.068 1.00 52.21  ? 731  VAL A C   1 
ATOM   4668  O O   . VAL A 1 731 ? 130.163 156.280 146.882 1.00 52.21  ? 731  VAL A O   1 
ATOM   4669  C CB  . VAL A 1 731 ? 129.114 158.976 148.256 1.00 52.21  ? 731  VAL A CB  1 
ATOM   4670  C CG1 . VAL A 1 731 ? 129.028 159.312 146.762 1.00 52.21  ? 731  VAL A CG1 1 
ATOM   4671  C CG2 . VAL A 1 731 ? 127.776 158.455 148.788 1.00 52.21  ? 731  VAL A CG2 1 
ATOM   4672  N N   . ASP A 1 732 ? 129.607 155.734 149.008 1.00 49.37  ? 732  ASP A N   1 
ATOM   4673  C CA  . ASP A 1 732 ? 129.614 154.284 148.841 1.00 49.37  ? 732  ASP A CA  1 
ATOM   4674  C C   . ASP A 1 732 ? 128.455 153.737 148.014 1.00 49.37  ? 732  ASP A C   1 
ATOM   4675  O O   . ASP A 1 732 ? 128.159 152.540 148.106 1.00 49.37  ? 732  ASP A O   1 
ATOM   4676  C CB  . ASP A 1 732 ? 129.605 153.624 150.221 1.00 49.37  ? 732  ASP A CB  1 
ATOM   4677  C CG  . ASP A 1 732 ? 128.279 153.804 150.945 1.00 49.37  ? 732  ASP A CG  1 
ATOM   4678  O OD1 . ASP A 1 732 ? 127.726 154.924 150.905 1.00 49.37  ? 732  ASP A OD1 1 
ATOM   4679  O OD2 . ASP A 1 732 ? 127.791 152.827 151.550 1.00 49.37  ? 732  ASP A OD2 1 
ATOM   4680  N N   . TYR A 1 733 ? 127.766 154.568 147.237 1.00 46.16  ? 733  TYR A N   1 
ATOM   4681  C CA  . TYR A 1 733 ? 126.775 154.062 146.289 1.00 46.16  ? 733  TYR A CA  1 
ATOM   4682  C C   . TYR A 1 733 ? 127.534 153.599 145.046 1.00 46.16  ? 733  TYR A C   1 
ATOM   4683  O O   . TYR A 1 733 ? 128.024 154.389 144.238 1.00 46.16  ? 733  TYR A O   1 
ATOM   4684  C CB  . TYR A 1 733 ? 125.737 155.128 145.937 1.00 30.00  ? 733  TYR A CB  1 
ATOM   4685  C CG  . TYR A 1 733 ? 124.740 154.690 144.886 1.00 30.00  ? 733  TYR A CG  1 
ATOM   4686  C CD1 . TYR A 1 733 ? 123.691 153.838 145.209 1.00 30.00  ? 733  TYR A CD1 1 
ATOM   4687  C CD2 . TYR A 1 733 ? 124.850 155.130 143.575 1.00 30.00  ? 733  TYR A CD2 1 
ATOM   4688  C CE1 . TYR A 1 733 ? 122.779 153.436 144.253 1.00 30.00  ? 733  TYR A CE1 1 
ATOM   4689  C CE2 . TYR A 1 733 ? 123.941 154.733 142.610 1.00 30.00  ? 733  TYR A CE2 1 
ATOM   4690  C CZ  . TYR A 1 733 ? 122.909 153.887 142.955 1.00 30.00  ? 733  TYR A CZ  1 
ATOM   4691  O OH  . TYR A 1 733 ? 122.002 153.486 142.000 1.00 30.00  ? 733  TYR A OH  1 
ATOM   4692  N N   . ARG A 1 734 ? 127.644 152.278 144.906 1.00 40.80  ? 734  ARG A N   1 
ATOM   4693  C CA  . ARG A 1 734 ? 128.624 151.673 144.011 1.00 40.80  ? 734  ARG A CA  1 
ATOM   4694  C C   . ARG A 1 734 ? 128.066 151.262 142.655 1.00 40.80  ? 734  ARG A C   1 
ATOM   4695  O O   . ARG A 1 734 ? 128.770 151.345 141.645 1.00 40.80  ? 734  ARG A O   1 
ATOM   4696  C CB  . ARG A 1 734 ? 129.244 150.448 144.680 1.00 40.80  ? 734  ARG A CB  1 
ATOM   4697  C CG  . ARG A 1 734 ? 129.869 150.722 146.024 1.00 40.80  ? 734  ARG A CG  1 
ATOM   4698  C CD  . ARG A 1 734 ? 131.041 151.651 145.883 1.00 40.80  ? 734  ARG A CD  1 
ATOM   4699  N NE  . ARG A 1 734 ? 132.014 151.105 144.950 1.00 40.80  ? 734  ARG A NE  1 
ATOM   4700  C CZ  . ARG A 1 734 ? 132.926 151.831 144.323 1.00 40.80  ? 734  ARG A CZ  1 
ATOM   4701  N NH1 . ARG A 1 734 ? 133.773 151.253 143.488 1.00 40.80  ? 734  ARG A NH1 1 
ATOM   4702  N NH2 . ARG A 1 734 ? 132.983 153.138 144.525 1.00 40.80  ? 734  ARG A NH2 1 
ATOM   4703  N N   . VAL A 1 735 ? 126.825 150.783 142.618 1.00 38.21  ? 735  VAL A N   1 
ATOM   4704  C CA  . VAL A 1 735 ? 126.299 150.151 141.413 1.00 38.21  ? 735  VAL A CA  1 
ATOM   4705  C C   . VAL A 1 735 ? 125.855 151.226 140.421 1.00 38.21  ? 735  VAL A C   1 
ATOM   4706  O O   . VAL A 1 735 ? 125.632 150.946 139.239 1.00 38.21  ? 735  VAL A O   1 
ATOM   4707  C CB  . VAL A 1 735 ? 125.156 149.173 141.756 1.00 38.21  ? 735  VAL A CB  1 
ATOM   4708  C CG1 . VAL A 1 735 ? 123.862 149.918 142.047 1.00 38.21  ? 735  VAL A CG1 1 
ATOM   4709  C CG2 . VAL A 1 735 ? 124.984 148.098 140.682 1.00 38.21  ? 735  VAL A CG2 1 
ATOM   4710  N N   . THR A 1 736 ? 125.739 152.471 140.881 1.00 33.89  ? 736  THR A N   1 
ATOM   4711  C CA  . THR A 1 736 ? 125.536 153.576 139.955 1.00 33.89  ? 736  THR A CA  1 
ATOM   4712  C C   . THR A 1 736 ? 126.844 153.921 139.256 1.00 33.89  ? 736  THR A C   1 
ATOM   4713  O O   . THR A 1 736 ? 126.843 154.475 138.155 1.00 33.89  ? 736  THR A O   1 
ATOM   4714  C CB  . THR A 1 736 ? 124.971 154.802 140.677 1.00 33.89  ? 736  THR A CB  1 
ATOM   4715  O OG1 . THR A 1 736 ? 125.006 155.934 139.801 1.00 33.89  ? 736  THR A OG1 1 
ATOM   4716  C CG2 . THR A 1 736 ? 125.764 155.111 141.931 1.00 33.89  ? 736  THR A CG2 1 
ATOM   4717  N N   . GLY A 1 737 ? 127.966 153.590 139.886 1.00 29.46  ? 737  GLY A N   1 
ATOM   4718  C CA  . GLY A 1 737 ? 129.266 153.878 139.324 1.00 29.46  ? 737  GLY A CA  1 
ATOM   4719  C C   . GLY A 1 737 ? 129.704 152.860 138.297 1.00 29.46  ? 737  GLY A C   1 
ATOM   4720  O O   . GLY A 1 737 ? 130.753 153.022 137.673 1.00 29.46  ? 737  GLY A O   1 
ATOM   4721  N N   . LEU A 1 738 ? 128.930 151.790 138.138 1.00 27.06  ? 738  LEU A N   1 
ATOM   4722  C CA  . LEU A 1 738 ? 129.169 150.798 137.102 1.00 27.06  ? 738  LEU A CA  1 
ATOM   4723  C C   . LEU A 1 738 ? 127.969 150.620 136.190 1.00 27.06  ? 738  LEU A C   1 
ATOM   4724  O O   . LEU A 1 738 ? 128.008 149.785 135.287 1.00 27.06  ? 738  LEU A O   1 
ATOM   4725  C CB  . LEU A 1 738 ? 129.555 149.454 137.725 1.00 27.06  ? 738  LEU A CB  1 
ATOM   4726  C CG  . LEU A 1 738 ? 130.486 148.544 136.927 1.00 27.06  ? 738  LEU A CG  1 
ATOM   4727  C CD1 . LEU A 1 738 ? 131.690 149.329 136.499 1.00 27.06  ? 738  LEU A CD1 1 
ATOM   4728  C CD2 . LEU A 1 738 ? 130.891 147.334 137.726 1.00 27.06  ? 738  LEU A CD2 1 
ATOM   4729  N N   . PHE A 1 739 ? 126.898 151.373 136.401 1.00 28.15  ? 739  PHE A N   1 
ATOM   4730  C CA  . PHE A 1 739 ? 125.817 151.403 135.431 1.00 28.15  ? 739  PHE A CA  1 
ATOM   4731  C C   . PHE A 1 739 ? 125.892 152.619 134.529 1.00 28.15  ? 739  PHE A C   1 
ATOM   4732  O O   . PHE A 1 739 ? 125.860 152.479 133.307 1.00 28.15  ? 739  PHE A O   1 
ATOM   4733  C CB  . PHE A 1 739 ? 124.458 151.373 136.127 1.00 28.15  ? 739  PHE A CB  1 
ATOM   4734  C CG  . PHE A 1 739 ? 123.297 151.506 135.188 1.00 28.15  ? 739  PHE A CG  1 
ATOM   4735  C CD1 . PHE A 1 739 ? 122.400 152.552 135.319 1.00 28.15  ? 739  PHE A CD1 1 
ATOM   4736  C CD2 . PHE A 1 739 ? 123.102 150.586 134.174 1.00 28.15  ? 739  PHE A CD2 1 
ATOM   4737  C CE1 . PHE A 1 739 ? 121.328 152.676 134.459 1.00 28.15  ? 739  PHE A CE1 1 
ATOM   4738  C CE2 . PHE A 1 739 ? 122.035 150.707 133.309 1.00 28.15  ? 739  PHE A CE2 1 
ATOM   4739  C CZ  . PHE A 1 739 ? 121.147 151.753 133.454 1.00 28.15  ? 739  PHE A CZ  1 
ATOM   4740  N N   . LEU A 1 740 ? 126.006 153.808 135.100 1.00 25.71  ? 740  LEU A N   1 
ATOM   4741  C CA  . LEU A 1 740 ? 126.160 155.019 134.315 1.00 25.71  ? 740  LEU A CA  1 
ATOM   4742  C C   . LEU A 1 740 ? 127.502 155.086 133.611 1.00 25.71  ? 740  LEU A C   1 
ATOM   4743  O O   . LEU A 1 740 ? 127.560 155.548 132.472 1.00 25.71  ? 740  LEU A O   1 
ATOM   4744  C CB  . LEU A 1 740 ? 125.978 156.247 135.205 1.00 25.71  ? 740  LEU A CB  1 
ATOM   4745  C CG  . LEU A 1 740 ? 124.517 156.564 135.516 1.00 25.71  ? 740  LEU A CG  1 
ATOM   4746  C CD1 . LEU A 1 740 ? 124.421 157.826 136.319 1.00 25.71  ? 740  LEU A CD1 1 
ATOM   4747  C CD2 . LEU A 1 740 ? 123.703 156.685 134.243 1.00 25.71  ? 740  LEU A CD2 1 
ATOM   4748  N N   . ALA A 1 741 ? 128.569 154.610 134.243 1.00 19.37  ? 741  ALA A N   1 
ATOM   4749  C CA  . ALA A 1 741 ? 129.871 154.552 133.605 1.00 19.37  ? 741  ALA A CA  1 
ATOM   4750  C C   . ALA A 1 741 ? 129.954 153.512 132.511 1.00 19.37  ? 741  ALA A C   1 
ATOM   4751  O O   . ALA A 1 741 ? 130.887 153.564 131.712 1.00 19.37  ? 741  ALA A O   1 
ATOM   4752  C CB  . ALA A 1 741 ? 130.953 154.251 134.631 1.00 19.37  ? 741  ALA A CB  1 
ATOM   4753  N N   . ALA A 1 742 ? 129.029 152.560 132.467 1.00 24.40  ? 742  ALA A N   1 
ATOM   4754  C CA  . ALA A 1 742 ? 128.907 151.651 131.341 1.00 24.40  ? 742  ALA A CA  1 
ATOM   4755  C C   . ALA A 1 742 ? 127.794 152.069 130.404 1.00 24.40  ? 742  ALA A C   1 
ATOM   4756  O O   . ALA A 1 742 ? 127.269 151.238 129.663 1.00 24.40  ? 742  ALA A O   1 
ATOM   4757  C CB  . ALA A 1 742 ? 128.683 150.224 131.824 1.00 24.40  ? 742  ALA A CB  1 
ATOM   4758  N N   . LEU A 1 743 ? 127.396 153.336 130.458 1.00 24.16  ? 743  LEU A N   1 
ATOM   4759  C CA  . LEU A 1 743 ? 126.548 153.950 129.450 1.00 24.16  ? 743  LEU A CA  1 
ATOM   4760  C C   . LEU A 1 743 ? 127.317 154.938 128.593 1.00 24.16  ? 743  LEU A C   1 
ATOM   4761  O O   . LEU A 1 743 ? 127.033 155.059 127.402 1.00 24.16  ? 743  LEU A O   1 
ATOM   4762  C CB  . LEU A 1 743 ? 125.360 154.658 130.104 1.00 24.16  ? 743  LEU A CB  1 
ATOM   4763  C CG  . LEU A 1 743 ? 124.129 153.815 130.401 1.00 24.16  ? 743  LEU A CG  1 
ATOM   4764  C CD1 . LEU A 1 743 ? 123.111 154.677 131.092 1.00 24.16  ? 743  LEU A CD1 1 
ATOM   4765  C CD2 . LEU A 1 743 ? 123.561 153.237 129.135 1.00 24.16  ? 743  LEU A CD2 1 
ATOM   4766  N N   . GLU A 1 744 ? 128.283 155.640 129.166 1.00 16.64  ? 744  GLU A N   1 
ATOM   4767  C CA  . GLU A 1 744 ? 129.190 156.449 128.379 1.00 16.64  ? 744  GLU A CA  1 
ATOM   4768  C C   . GLU A 1 744 ? 130.074 155.595 127.484 1.00 16.64  ? 744  GLU A C   1 
ATOM   4769  O O   . GLU A 1 744 ? 130.373 156.001 126.358 1.00 16.64  ? 744  GLU A O   1 
ATOM   4770  C CB  . GLU A 1 744 ? 130.018 157.331 129.314 1.00 16.64  ? 744  GLU A CB  1 
ATOM   4771  C CG  . GLU A 1 744 ? 131.338 157.855 128.787 1.00 16.64  ? 744  GLU A CG  1 
ATOM   4772  C CD  . GLU A 1 744 ? 131.211 158.817 127.606 1.00 16.64  ? 744  GLU A CD  1 
ATOM   4773  O OE1 . GLU A 1 744 ? 130.142 159.433 127.416 1.00 16.64  ? 744  GLU A OE1 1 
ATOM   4774  O OE2 . GLU A 1 744 ? 132.204 158.976 126.867 1.00 16.64  ? 744  GLU A OE2 1 
ATOM   4775  N N   . VAL A 1 745 ? 130.446 154.392 127.925 1.00 17.92  ? 745  VAL A N   1 
ATOM   4776  C CA  . VAL A 1 745 ? 131.128 153.436 127.052 1.00 17.92  ? 745  VAL A CA  1 
ATOM   4777  C C   . VAL A 1 745 ? 130.189 152.887 125.979 1.00 17.92  ? 745  VAL A C   1 
ATOM   4778  O O   . VAL A 1 745 ? 130.651 152.468 124.918 1.00 17.92  ? 745  VAL A O   1 
ATOM   4779  C CB  . VAL A 1 745 ? 131.752 152.328 127.922 1.00 17.92  ? 745  VAL A CB  1 
ATOM   4780  C CG1 . VAL A 1 745 ? 132.637 151.417 127.145 1.00 17.92  ? 745  VAL A CG1 1 
ATOM   4781  C CG2 . VAL A 1 745 ? 132.577 152.945 128.998 1.00 17.92  ? 745  VAL A CG2 1 
ATOM   4782  N N   . ILE A 1 746 ? 128.870 152.916 126.205 1.00 20.69  ? 746  ILE A N   1 
ATOM   4783  C CA  . ILE A 1 746 ? 127.898 152.584 125.163 1.00 20.69  ? 746  ILE A CA  1 
ATOM   4784  C C   . ILE A 1 746 ? 127.608 153.784 124.277 1.00 20.69  ? 746  ILE A C   1 
ATOM   4785  O O   . ILE A 1 746 ? 127.333 153.611 123.078 1.00 20.69  ? 746  ILE A O   1 
ATOM   4786  C CB  . ILE A 1 746 ? 126.639 151.997 125.835 1.00 20.69  ? 746  ILE A CB  1 
ATOM   4787  C CG1 . ILE A 1 746 ? 126.983 150.625 126.409 1.00 20.69  ? 746  ILE A CG1 1 
ATOM   4788  C CG2 . ILE A 1 746 ? 125.458 151.876 124.893 1.00 20.69  ? 746  ILE A CG2 1 
ATOM   4789  C CD1 . ILE A 1 746 ? 125.808 149.796 126.879 1.00 20.69  ? 746  ILE A CD1 1 
ATOM   4790  N N   . ARG A 1 747 ? 127.745 155.002 124.805 1.00 35.55  ? 747  ARG A N   1 
ATOM   4791  C CA  . ARG A 1 747 ? 127.558 156.209 124.006 1.00 35.55  ? 747  ARG A CA  1 
ATOM   4792  C C   . ARG A 1 747 ? 128.591 156.324 122.903 1.00 35.55  ? 747  ARG A C   1 
ATOM   4793  O O   . ARG A 1 747 ? 128.230 156.410 121.731 1.00 35.55  ? 747  ARG A O   1 
ATOM   4794  C CB  . ARG A 1 747 ? 127.619 157.447 124.883 1.00 35.55  ? 747  ARG A CB  1 
ATOM   4795  C CG  . ARG A 1 747 ? 127.606 158.682 124.069 1.00 35.55  ? 747  ARG A CG  1 
ATOM   4796  C CD  . ARG A 1 747 ? 127.924 159.890 124.885 1.00 35.55  ? 747  ARG A CD  1 
ATOM   4797  N NE  . ARG A 1 747 ? 129.343 160.058 125.136 1.00 35.55  ? 747  ARG A NE  1 
ATOM   4798  C CZ  . ARG A 1 747 ? 130.214 160.521 124.253 1.00 35.55  ? 747  ARG A CZ  1 
ATOM   4799  N NH1 . ARG A 1 747 ? 129.841 160.828 123.023 1.00 35.55  ? 747  ARG A NH1 1 
ATOM   4800  N NH2 . ARG A 1 747 ? 131.476 160.653 124.601 1.00 35.55  ? 747  ARG A NH2 1 
ATOM   4801  N N   . ARG A 1 748 ? 129.867 156.322 123.243 1.00 35.55  ? 748  ARG A N   1 
ATOM   4802  C CA  . ARG A 1 748 ? 130.893 156.185 122.224 1.00 35.55  ? 748  ARG A CA  1 
ATOM   4803  C C   . ARG A 1 748 ? 130.872 154.747 121.763 1.00 35.55  ? 748  ARG A C   1 
ATOM   4804  O O   . ARG A 1 748 ? 131.105 153.834 122.543 1.00 35.55  ? 748  ARG A O   1 
ATOM   4805  C CB  . ARG A 1 748 ? 132.252 156.545 122.768 1.00 35.55  ? 748  ARG A CB  1 
ATOM   4806  C CG  . ARG A 1 748 ? 133.276 156.601 121.732 1.00 35.55  ? 748  ARG A CG  1 
ATOM   4807  C CD  . ARG A 1 748 ? 134.493 157.008 122.410 1.00 35.55  ? 748  ARG A CD  1 
ATOM   4808  N NE  . ARG A 1 748 ? 134.250 158.252 123.100 1.00 35.55  ? 748  ARG A NE  1 
ATOM   4809  C CZ  . ARG A 1 748 ? 134.412 159.443 122.563 1.00 35.55  ? 748  ARG A CZ  1 
ATOM   4810  N NH1 . ARG A 1 748 ? 134.881 159.552 121.339 1.00 35.55  ? 748  ARG A NH1 1 
ATOM   4811  N NH2 . ARG A 1 748 ? 134.162 160.518 123.272 1.00 35.55  ? 748  ARG A NH2 1 
ATOM   4812  N N   . GLY A 1 749 ? 130.624 154.535 120.490 1.00 27.22  ? 749  GLY A N   1 
ATOM   4813  C CA  . GLY A 1 749 ? 130.307 153.215 120.022 1.00 27.22  ? 749  GLY A CA  1 
ATOM   4814  C C   . GLY A 1 749 ? 129.247 153.416 118.982 1.00 27.22  ? 749  GLY A C   1 
ATOM   4815  O O   . GLY A 1 749 ? 129.143 152.637 118.036 1.00 27.22  ? 749  GLY A O   1 
ATOM   4816  N N   . GLN A 1 750 ? 128.449 154.471 119.152 1.00 29.19  ? 750  GLN A N   1 
ATOM   4817  C CA  . GLN A 1 750 ? 127.744 155.065 118.029 1.00 29.19  ? 750  GLN A CA  1 
ATOM   4818  C C   . GLN A 1 750 ? 128.372 156.367 117.586 1.00 29.19  ? 750  GLN A C   1 
ATOM   4819  O O   . GLN A 1 750 ? 128.105 156.813 116.474 1.00 29.19  ? 750  GLN A O   1 
ATOM   4820  C CB  . GLN A 1 750 ? 126.275 155.326 118.351 1.00 29.19  ? 750  GLN A CB  1 
ATOM   4821  C CG  . GLN A 1 750 ? 126.044 156.447 119.312 1.00 29.19  ? 750  GLN A CG  1 
ATOM   4822  C CD  . GLN A 1 750 ? 124.588 156.744 119.490 1.00 29.19  ? 750  GLN A CD  1 
ATOM   4823  O OE1 . GLN A 1 750 ? 123.739 156.162 118.816 1.00 29.19  ? 750  GLN A OE1 1 
ATOM   4824  N NE2 . GLN A 1 750 ? 124.281 157.658 120.396 1.00 29.19  ? 750  GLN A NE2 1 
ATOM   4825  N N   . TRP A 1 751 ? 129.183 156.988 118.426 1.00 35.55  ? 751  TRP A N   1 
ATOM   4826  C CA  . TRP A 1 751 ? 130.006 158.075 117.949 1.00 35.55  ? 751  TRP A CA  1 
ATOM   4827  C C   . TRP A 1 751 ? 131.065 157.570 116.994 1.00 35.55  ? 751  TRP A C   1 
ATOM   4828  O O   . TRP A 1 751 ? 131.458 158.304 116.091 1.00 35.55  ? 751  TRP A O   1 
ATOM   4829  C CB  . TRP A 1 751 ? 130.659 158.796 119.119 1.00 35.55  ? 751  TRP A CB  1 
ATOM   4830  C CG  . TRP A 1 751 ? 131.558 159.934 118.763 1.00 35.55  ? 751  TRP A CG  1 
ATOM   4831  C CD1 . TRP A 1 751 ? 131.234 161.239 118.795 1.00 35.55  ? 751  TRP A CD1 1 
ATOM   4832  C CD2 . TRP A 1 751 ? 132.940 159.875 118.387 1.00 35.55  ? 751  TRP A CD2 1 
ATOM   4833  N NE1 . TRP A 1 751 ? 132.304 162.003 118.436 1.00 35.55  ? 751  TRP A NE1 1 
ATOM   4834  C CE2 . TRP A 1 751 ? 133.366 161.183 118.181 1.00 35.55  ? 751  TRP A CE2 1 
ATOM   4835  C CE3 . TRP A 1 751 ? 133.851 158.841 118.193 1.00 35.55  ? 751  TRP A CE3 1 
ATOM   4836  C CZ2 . TRP A 1 751 ? 134.652 161.486 117.789 1.00 35.55  ? 751  TRP A CZ2 1 
ATOM   4837  C CZ3 . TRP A 1 751 ? 135.112 159.141 117.795 1.00 35.55  ? 751  TRP A CZ3 1 
ATOM   4838  C CH2 . TRP A 1 751 ? 135.510 160.448 117.600 1.00 35.55  ? 751  TRP A CH2 1 
ATOM   4839  N N   . ASN A 1 752 ? 131.573 156.349 117.188 1.00 33.27  ? 752  ASN A N   1 
ATOM   4840  C CA  . ASN A 1 752 ? 132.570 155.806 116.267 1.00 33.27  ? 752  ASN A CA  1 
ATOM   4841  C C   . ASN A 1 752 ? 131.986 155.578 114.890 1.00 33.27  ? 752  ASN A C   1 
ATOM   4842  O O   . ASN A 1 752 ? 132.703 155.653 113.893 1.00 33.27  ? 752  ASN A O   1 
ATOM   4843  C CB  . ASN A 1 752 ? 133.121 154.482 116.775 1.00 33.27  ? 752  ASN A CB  1 
ATOM   4844  C CG  . ASN A 1 752 ? 133.814 154.610 118.075 1.00 33.27  ? 752  ASN A CG  1 
ATOM   4845  O OD1 . ASN A 1 752 ? 134.293 155.675 118.422 1.00 33.27  ? 752  ASN A OD1 1 
ATOM   4846  N ND2 . ASN A 1 752 ? 133.895 153.519 118.809 1.00 33.27  ? 752  ASN A ND2 1 
ATOM   4847  N N   . PHE A 1 753 ? 130.698 155.279 114.826 1.00 30.49  ? 753  PHE A N   1 
ATOM   4848  C CA  . PHE A 1 753 ? 130.059 155.081 113.542 1.00 30.49  ? 753  PHE A CA  1 
ATOM   4849  C C   . PHE A 1 753 ? 129.988 156.380 112.755 1.00 30.49  ? 753  PHE A C   1 
ATOM   4850  O O   . PHE A 1 753 ? 130.554 156.484 111.662 1.00 30.49  ? 753  PHE A O   1 
ATOM   4851  C CB  . PHE A 1 753 ? 128.668 154.507 113.745 1.00 30.49  ? 753  PHE A CB  1 
ATOM   4852  C CG  . PHE A 1 753 ? 128.112 153.895 112.524 1.00 30.49  ? 753  PHE A CG  1 
ATOM   4853  C CD1 . PHE A 1 753 ? 128.890 153.049 111.763 1.00 30.49  ? 753  PHE A CD1 1 
ATOM   4854  C CD2 . PHE A 1 753 ? 126.828 154.170 112.119 1.00 30.49  ? 753  PHE A CD2 1 
ATOM   4855  C CE1 . PHE A 1 753 ? 128.401 152.477 110.635 1.00 30.49  ? 753  PHE A CE1 1 
ATOM   4856  C CE2 . PHE A 1 753 ? 126.333 153.602 110.981 1.00 30.49  ? 753  PHE A CE2 1 
ATOM   4857  C CZ  . PHE A 1 753 ? 127.124 152.754 110.235 1.00 30.49  ? 753  PHE A CZ  1 
ATOM   4858  N N   . TYR A 1 754 ? 129.336 157.395 113.310 1.00 35.55  ? 754  TYR A N   1 
ATOM   4859  C CA  . TYR A 1 754 ? 129.073 158.623 112.590 1.00 35.55  ? 754  TYR A CA  1 
ATOM   4860  C C   . TYR A 1 754 ? 130.270 159.547 112.538 1.00 35.55  ? 754  TYR A C   1 
ATOM   4861  O O   . TYR A 1 754 ? 130.189 160.604 111.924 1.00 35.55  ? 754  TYR A O   1 
ATOM   4862  C CB  . TYR A 1 754 ? 127.885 159.339 113.205 1.00 35.55  ? 754  TYR A CB  1 
ATOM   4863  C CG  . TYR A 1 754 ? 126.611 158.575 113.053 1.00 35.55  ? 754  TYR A CG  1 
ATOM   4864  C CD1 . TYR A 1 754 ? 125.967 158.510 111.839 1.00 35.55  ? 754  TYR A CD1 1 
ATOM   4865  C CD2 . TYR A 1 754 ? 126.046 157.919 114.123 1.00 35.55  ? 754  TYR A CD2 1 
ATOM   4866  C CE1 . TYR A 1 754 ? 124.795 157.808 111.696 1.00 35.55  ? 754  TYR A CE1 1 
ATOM   4867  C CE2 . TYR A 1 754 ? 124.875 157.217 113.989 1.00 35.55  ? 754  TYR A CE2 1 
ATOM   4868  C CZ  . TYR A 1 754 ? 124.256 157.164 112.776 1.00 35.55  ? 754  TYR A CZ  1 
ATOM   4869  O OH  . TYR A 1 754 ? 123.086 156.461 112.646 1.00 35.55  ? 754  TYR A OH  1 
ATOM   4870  N N   . ARG A 1 755 ? 131.375 159.194 113.161 1.00 35.55  ? 755  ARG A N   1 
ATOM   4871  C CA  . ARG A 1 755 ? 132.596 159.918 112.888 1.00 35.55  ? 755  ARG A CA  1 
ATOM   4872  C C   . ARG A 1 755 ? 133.323 159.355 111.682 1.00 35.55  ? 755  ARG A C   1 
ATOM   4873  O O   . ARG A 1 755 ? 133.917 160.123 110.919 1.00 35.55  ? 755  ARG A O   1 
ATOM   4874  C CB  . ARG A 1 755 ? 133.508 159.902 114.115 1.00 35.55  ? 755  ARG A CB  1 
ATOM   4875  C CG  . ARG A 1 755 ? 134.888 160.471 113.943 1.00 35.55  ? 755  ARG A CG  1 
ATOM   4876  C CD  . ARG A 1 755 ? 134.894 161.896 113.449 1.00 35.55  ? 755  ARG A CD  1 
ATOM   4877  N NE  . ARG A 1 755 ? 136.126 162.146 112.718 1.00 35.55  ? 755  ARG A NE  1 
ATOM   4878  C CZ  . ARG A 1 755 ? 136.741 163.319 112.659 1.00 35.55  ? 755  ARG A CZ  1 
ATOM   4879  N NH1 . ARG A 1 755 ? 136.233 164.369 113.285 1.00 35.55  ? 755  ARG A NH1 1 
ATOM   4880  N NH2 . ARG A 1 755 ? 137.870 163.439 111.975 1.00 35.55  ? 755  ARG A NH2 1 
ATOM   4881  N N   . LEU A 1 756 ? 133.248 158.048 111.450 1.00 24.23  ? 756  LEU A N   1 
ATOM   4882  C CA  . LEU A 1 756 ? 133.847 157.435 110.272 1.00 24.23  ? 756  LEU A CA  1 
ATOM   4883  C C   . LEU A 1 756 ? 132.994 157.547 109.027 1.00 24.23  ? 756  LEU A C   1 
ATOM   4884  O O   . LEU A 1 756 ? 133.550 157.687 107.938 1.00 24.23  ? 756  LEU A O   1 
ATOM   4885  C CB  . LEU A 1 756 ? 134.159 155.960 110.528 1.00 24.23  ? 756  LEU A CB  1 
ATOM   4886  C CG  . LEU A 1 756 ? 135.609 155.675 110.877 1.00 24.23  ? 756  LEU A CG  1 
ATOM   4887  C CD1 . LEU A 1 756 ? 136.392 155.992 109.671 1.00 24.23  ? 756  LEU A CD1 1 
ATOM   4888  C CD2 . LEU A 1 756 ? 136.127 156.501 112.012 1.00 24.23  ? 756  LEU A CD2 1 
ATOM   4889  N N   . GLU A 1 757 ? 131.669 157.474 109.159 1.00 29.93  ? 757  GLU A N   1 
ATOM   4890  C CA  . GLU A 1 757 ? 130.788 157.739 108.029 1.00 29.93  ? 757  GLU A CA  1 
ATOM   4891  C C   . GLU A 1 757 ? 130.982 159.156 107.514 1.00 29.93  ? 757  GLU A C   1 
ATOM   4892  O O   . GLU A 1 757 ? 131.076 159.381 106.306 1.00 29.93  ? 757  GLU A O   1 
ATOM   4893  C CB  . GLU A 1 757 ? 129.340 157.497 108.437 1.00 29.93  ? 757  GLU A CB  1 
ATOM   4894  C CG  . GLU A 1 757 ? 128.351 158.248 107.601 1.00 29.93  ? 757  GLU A CG  1 
ATOM   4895  C CD  . GLU A 1 757 ? 126.934 158.054 108.050 1.00 29.93  ? 757  GLU A CD  1 
ATOM   4896  O OE1 . GLU A 1 757 ? 126.529 156.893 108.245 1.00 29.93  ? 757  GLU A OE1 1 
ATOM   4897  O OE2 . GLU A 1 757 ? 126.214 159.061 108.195 1.00 29.93  ? 757  GLU A OE2 1 
ATOM   4898  N N   . ASN A 1 758 ? 131.102 160.114 108.431 1.00 25.02  ? 758  ASN A N   1 
ATOM   4899  C CA  . ASN A 1 758 ? 131.358 161.499 108.063 1.00 25.02  ? 758  ASN A CA  1 
ATOM   4900  C C   . ASN A 1 758 ? 132.710 161.678 107.405 1.00 25.02  ? 758  ASN A C   1 
ATOM   4901  O O   . ASN A 1 758 ? 132.800 162.347 106.376 1.00 25.02  ? 758  ASN A O   1 
ATOM   4902  C CB  . ASN A 1 758 ? 131.292 162.404 109.281 1.00 25.02  ? 758  ASN A CB  1 
ATOM   4903  C CG  . ASN A 1 758 ? 131.688 163.819 108.957 1.00 25.02  ? 758  ASN A CG  1 
ATOM   4904  O OD1 . ASN A 1 758 ? 130.988 164.503 108.224 1.00 25.02  ? 758  ASN A OD1 1 
ATOM   4905  N ND2 . ASN A 1 758 ? 132.820 164.265 109.484 1.00 25.02  ? 758  ASN A ND2 1 
ATOM   4906  N N   . GLU A 1 759 ? 133.766 161.101 107.961 1.00 19.29  ? 759  GLU A N   1 
ATOM   4907  C CA  . GLU A 1 759 ? 135.066 161.245 107.328 1.00 19.29  ? 759  GLU A CA  1 
ATOM   4908  C C   . GLU A 1 759 ? 135.355 160.138 106.329 1.00 19.29  ? 759  GLU A C   1 
ATOM   4909  O O   . GLU A 1 759 ? 136.526 159.834 106.092 1.00 19.29  ? 759  GLU A O   1 
ATOM   4910  C CB  . GLU A 1 759 ? 136.180 161.322 108.370 1.00 19.29  ? 759  GLU A CB  1 
ATOM   4911  C CG  . GLU A 1 759 ? 136.239 162.674 109.083 1.00 19.29  ? 759  GLU A CG  1 
ATOM   4912  C CD  . GLU A 1 759 ? 136.725 163.824 108.198 1.00 19.29  ? 759  GLU A CD  1 
ATOM   4913  O OE1 . GLU A 1 759 ? 137.644 163.603 107.385 1.00 19.29  ? 759  GLU A OE1 1 
ATOM   4914  O OE2 . GLU A 1 759 ? 136.194 164.952 108.318 1.00 19.29  ? 759  GLU A OE2 1 
ATOM   4915  N N   . HIS A 1 760 ? 134.317 159.511 105.770 1.00 22.64  ? 760  HIS A N   1 
ATOM   4916  C CA  . HIS A 1 760 ? 134.386 158.886 104.455 1.00 22.64  ? 760  HIS A CA  1 
ATOM   4917  C C   . HIS A 1 760 ? 133.534 159.612 103.426 1.00 22.64  ? 760  HIS A C   1 
ATOM   4918  O O   . HIS A 1 760 ? 134.007 159.855 102.313 1.00 22.64  ? 760  HIS A O   1 
ATOM   4919  C CB  . HIS A 1 760 ? 133.952 157.422 104.505 1.00 22.64  ? 760  HIS A CB  1 
ATOM   4920  C CG  . HIS A 1 760 ? 134.224 156.680 103.234 1.00 22.64  ? 760  HIS A CG  1 
ATOM   4921  N ND1 . HIS A 1 760 ? 133.228 156.099 102.484 1.00 22.64  ? 760  HIS A ND1 1 
ATOM   4922  C CD2 . HIS A 1 760 ? 135.380 156.438 102.572 1.00 22.64  ? 760  HIS A CD2 1 
ATOM   4923  C CE1 . HIS A 1 760 ? 133.757 155.520 101.421 1.00 22.64  ? 760  HIS A CE1 1 
ATOM   4924  N NE2 . HIS A 1 760 ? 135.062 155.711 101.451 1.00 22.64  ? 760  HIS A NE2 1 
ATOM   4925  N N   . LEU A 1 761 ? 132.308 160.016 103.791 1.00 18.12  ? 761  LEU A N   1 
ATOM   4926  C CA  . LEU A 1 761 ? 131.523 160.905 102.938 1.00 18.12  ? 761  LEU A CA  1 
ATOM   4927  C C   . LEU A 1 761 ? 132.082 162.318 102.898 1.00 18.12  ? 761  LEU A C   1 
ATOM   4928  O O   . LEU A 1 761 ? 131.527 163.174 102.206 1.00 18.12  ? 761  LEU A O   1 
ATOM   4929  C CB  . LEU A 1 761 ? 130.070 160.984 103.385 1.00 18.12  ? 761  LEU A CB  1 
ATOM   4930  C CG  . LEU A 1 761 ? 129.132 159.817 103.152 1.00 18.12  ? 761  LEU A CG  1 
ATOM   4931  C CD1 . LEU A 1 761 ? 127.745 160.200 103.639 1.00 18.12  ? 761  LEU A CD1 1 
ATOM   4932  C CD2 . LEU A 1 761 ? 129.119 159.482 101.688 1.00 18.12  ? 761  LEU A CD2 1 
ATOM   4933  N N   . ASN A 1 762 ? 133.124 162.609 103.667 1.00 17.23  ? 762  ASN A N   1 
ATOM   4934  C CA  . ASN A 1 762 ? 133.991 163.740 103.392 1.00 17.23  ? 762  ASN A CA  1 
ATOM   4935  C C   . ASN A 1 762 ? 135.450 163.308 103.321 1.00 17.23  ? 762  ASN A C   1 
ATOM   4936  O O   . ASN A 1 762 ? 136.346 164.048 103.741 1.00 17.23  ? 762  ASN A O   1 
ATOM   4937  C CB  . ASN A 1 762 ? 133.744 164.832 104.422 1.00 17.23  ? 762  ASN A CB  1 
ATOM   4938  C CG  . ASN A 1 762 ? 132.282 165.250 104.453 1.00 17.23  ? 762  ASN A CG  1 
ATOM   4939  O OD1 . ASN A 1 762 ? 131.556 164.961 105.396 1.00 17.23  ? 762  ASN A OD1 1 
ATOM   4940  N ND2 . ASN A 1 762 ? 131.838 165.903 103.393 1.00 17.23  ? 762  ASN A ND2 1 
ATOM   4941  N N   . ASN A 1 763 ? 135.680 162.090 102.813 1.00 32.54  ? 763  ASN A N   1 
ATOM   4942  C CA  . ASN A 1 763 ? 136.948 161.631 102.254 1.00 32.54  ? 763  ASN A CA  1 
ATOM   4943  C C   . ASN A 1 763 ? 136.873 161.352 100.756 1.00 32.54  ? 763  ASN A C   1 
ATOM   4944  O O   . ASN A 1 763 ? 137.901 161.440 100.075 1.00 32.54  ? 763  ASN A O   1 
ATOM   4945  C CB  . ASN A 1 763 ? 137.426 160.363 102.969 1.00 32.54  ? 763  ASN A CB  1 
ATOM   4946  C CG  . ASN A 1 763 ? 138.921 160.159 102.860 1.00 32.54  ? 763  ASN A CG  1 
ATOM   4947  O OD1 . ASN A 1 763 ? 139.666 161.075 102.531 1.00 32.54  ? 763  ASN A OD1 1 
ATOM   4948  N ND2 . ASN A 1 763 ? 139.368 158.955 103.156 1.00 32.54  ? 763  ASN A ND2 1 
ATOM   4949  N N   . ALA A 1 764 ? 135.689 160.961 100.256 1.00 36.08  ? 764  ALA A N   1 
ATOM   4950  C CA  . ALA A 1 764 ? 135.289 160.907 98.845  1.00 36.08  ? 764  ALA A CA  1 
ATOM   4951  C C   . ALA A 1 764 ? 135.980 159.821 98.014  1.00 36.08  ? 764  ALA A C   1 
ATOM   4952  O O   . ALA A 1 764 ? 135.733 159.721 96.808  1.00 36.08  ? 764  ALA A O   1 
ATOM   4953  C CB  . ALA A 1 764 ? 135.479 162.278 98.182  1.00 36.08  ? 764  ALA A CB  1 
ATOM   4954  N N   . GLY A 1 765 ? 136.838 159.007 98.630  1.00 39.53  ? 765  GLY A N   1 
ATOM   4955  C CA  . GLY A 1 765 ? 137.429 157.853 97.970  1.00 39.53  ? 765  GLY A CA  1 
ATOM   4956  C C   . GLY A 1 765 ? 136.779 156.559 98.422  1.00 39.53  ? 765  GLY A C   1 
ATOM   4957  O O   . GLY A 1 765 ? 136.126 156.542 99.469  1.00 39.53  ? 765  GLY A O   1 
ATOM   4958  N N   . LYS A 1 766 ? 136.933 155.471 97.657  1.00 42.95  ? 766  LYS A N   1 
ATOM   4959  C CA  . LYS A 1 766 ? 136.245 154.218 97.972  1.00 42.95  ? 766  LYS A CA  1 
ATOM   4960  C C   . LYS A 1 766 ? 137.186 153.024 97.813  1.00 42.95  ? 766  LYS A C   1 
ATOM   4961  O O   . LYS A 1 766 ? 136.820 151.996 97.235  1.00 42.95  ? 766  LYS A O   1 
ATOM   4962  C CB  . LYS A 1 766 ? 134.985 154.046 97.122  1.00 42.95  ? 766  LYS A CB  1 
ATOM   4963  C CG  . LYS A 1 766 ? 133.806 154.869 97.623  1.00 42.95  ? 766  LYS A CG  1 
ATOM   4964  C CD  . LYS A 1 766 ? 132.702 154.972 96.592  1.00 42.95  ? 766  LYS A CD  1 
ATOM   4965  C CE  . LYS A 1 766 ? 133.019 156.010 95.525  1.00 42.95  ? 766  LYS A CE  1 
ATOM   4966  N NZ  . LYS A 1 766 ? 132.986 157.404 96.042  1.00 42.95  ? 766  LYS A NZ  1 
ATOM   4967  N N   . PHE A 1 767 ? 138.389 153.136 98.367  1.00 38.86  ? 767  PHE A N   1 
ATOM   4968  C CA  . PHE A 1 767 ? 139.456 152.147 98.216  1.00 38.86  ? 767  PHE A CA  1 
ATOM   4969  C C   . PHE A 1 767 ? 139.137 150.908 99.039  1.00 38.86  ? 767  PHE A C   1 
ATOM   4970  O O   . PHE A 1 767 ? 139.694 150.718 100.122 1.00 38.86  ? 767  PHE A O   1 
ATOM   4971  C CB  . PHE A 1 767 ? 140.794 152.693 98.712  1.00 38.86  ? 767  PHE A CB  1 
ATOM   4972  C CG  . PHE A 1 767 ? 141.317 153.897 97.991  1.00 38.86  ? 767  PHE A CG  1 
ATOM   4973  C CD1 . PHE A 1 767 ? 142.422 153.775 97.184  1.00 38.86  ? 767  PHE A CD1 1 
ATOM   4974  C CD2 . PHE A 1 767 ? 140.779 155.157 98.190  1.00 38.86  ? 767  PHE A CD2 1 
ATOM   4975  C CE1 . PHE A 1 767 ? 142.947 154.865 96.549  1.00 38.86  ? 767  PHE A CE1 1 
ATOM   4976  C CE2 . PHE A 1 767 ? 141.297 156.255 97.545  1.00 38.86  ? 767  PHE A CE2 1 
ATOM   4977  C CZ  . PHE A 1 767 ? 142.384 156.107 96.721  1.00 38.86  ? 767  PHE A CZ  1 
ATOM   4978  N N   . ARG A 1 768 ? 138.282 150.026 98.538  1.00 45.85  ? 768  ARG A N   1 
ATOM   4979  C CA  . ARG A 1 768 ? 138.075 148.748 99.219  1.00 45.85  ? 768  ARG A CA  1 
ATOM   4980  C C   . ARG A 1 768 ? 138.984 147.681 98.612  1.00 45.85  ? 768  ARG A C   1 
ATOM   4981  O O   . ARG A 1 768 ? 138.814 147.238 97.477  1.00 45.85  ? 768  ARG A O   1 
ATOM   4982  C CB  . ARG A 1 768 ? 136.611 148.332 99.160  1.00 45.85  ? 768  ARG A CB  1 
ATOM   4983  C CG  . ARG A 1 768 ? 135.897 148.417 100.485 1.00 45.85  ? 768  ARG A CG  1 
ATOM   4984  C CD  . ARG A 1 768 ? 134.471 147.932 100.344 1.00 45.85  ? 768  ARG A CD  1 
ATOM   4985  N NE  . ARG A 1 768 ? 133.671 148.855 99.547  1.00 45.85  ? 768  ARG A NE  1 
ATOM   4986  C CZ  . ARG A 1 768 ? 132.673 148.485 98.752  1.00 45.85  ? 768  ARG A CZ  1 
ATOM   4987  N NH1 . ARG A 1 768 ? 132.343 147.206 98.654  1.00 45.85  ? 768  ARG A NH1 1 
ATOM   4988  N NH2 . ARG A 1 768 ? 132.004 149.396 98.058  1.00 45.85  ? 768  ARG A NH2 1 
ATOM   4989  N N   . ALA A 1 769 ? 139.971 147.266 99.408  1.00 50.31  ? 769  ALA A N   1 
ATOM   4990  C CA  . ALA A 1 769 ? 140.664 146.012 99.141  1.00 50.31  ? 769  ALA A CA  1 
ATOM   4991  C C   . ALA A 1 769 ? 139.665 144.892 99.383  1.00 50.31  ? 769  ALA A C   1 
ATOM   4992  O O   . ALA A 1 769 ? 138.710 145.089 100.142 1.00 50.31  ? 769  ALA A O   1 
ATOM   4993  C CB  . ALA A 1 769 ? 141.903 145.852 100.020 1.00 50.31  ? 769  ALA A CB  1 
ATOM   4994  N N   . VAL A 1 770 ? 139.913 143.717 98.797  1.00 52.40  ? 770  VAL A N   1 
ATOM   4995  C CA  . VAL A 1 770 ? 138.875 142.748 98.440  1.00 52.40  ? 770  VAL A CA  1 
ATOM   4996  C C   . VAL A 1 770 ? 138.017 142.290 99.618  1.00 52.40  ? 770  VAL A C   1 
ATOM   4997  O O   . VAL A 1 770 ? 138.489 141.654 100.566 1.00 52.40  ? 770  VAL A O   1 
ATOM   4998  C CB  . VAL A 1 770 ? 139.512 141.556 97.689  1.00 52.40  ? 770  VAL A CB  1 
ATOM   4999  C CG1 . VAL A 1 770 ? 140.750 141.003 98.413  1.00 52.40  ? 770  VAL A CG1 1 
ATOM   5000  C CG2 . VAL A 1 770 ? 138.482 140.457 97.461  1.00 52.40  ? 770  VAL A CG2 1 
ATOM   5001  N N   . LYS A 1 771 ? 136.752 142.702 99.591  1.00 53.96  ? 771  LYS A N   1 
ATOM   5002  C CA  . LYS A 1 771 ? 135.788 142.292 100.597 1.00 53.96  ? 771  LYS A CA  1 
ATOM   5003  C C   . LYS A 1 771 ? 134.635 141.535 99.949  1.00 53.96  ? 771  LYS A C   1 
ATOM   5004  O O   . LYS A 1 771 ? 134.401 140.363 100.259 1.00 53.96  ? 771  LYS A O   1 
ATOM   5005  C CB  . LYS A 1 771 ? 135.291 143.520 101.365 1.00 53.96  ? 771  LYS A CB  1 
ATOM   5006  C CG  . LYS A 1 771 ? 134.028 143.309 102.186 1.00 53.96  ? 771  LYS A CG  1 
ATOM   5007  C CD  . LYS A 1 771 ? 133.260 144.607 102.333 1.00 53.96  ? 771  LYS A CD  1 
ATOM   5008  C CE  . LYS A 1 771 ? 131.906 144.374 102.955 1.00 53.96  ? 771  LYS A CE  1 
ATOM   5009  N NZ  . LYS A 1 771 ? 131.096 143.415 102.175 1.00 53.96  ? 771  LYS A NZ  1 
ATOM   5010  N N   . THR A 1 772 ? 133.953 142.184 99.009  1.00 67.07  ? 772  THR A N   1 
ATOM   5011  C CA  . THR A 1 772 ? 132.788 141.622 98.327  1.00 67.07  ? 772  THR A CA  1 
ATOM   5012  C C   . THR A 1 772 ? 132.637 142.211 96.930  1.00 67.07  ? 772  THR A C   1 
ATOM   5013  O O   . THR A 1 772 ? 132.291 143.383 96.771  1.00 67.07  ? 772  THR A O   1 
ATOM   5014  C CB  . THR A 1 772 ? 131.474 141.871 99.105  1.00 67.07  ? 772  THR A CB  1 
ATOM   5015  O OG1 . THR A 1 772 ? 131.267 143.280 99.276  1.00 67.07  ? 772  THR A OG1 1 
ATOM   5016  C CG2 . THR A 1 772 ? 131.463 141.153 100.450 1.00 67.07  ? 772  THR A CG2 1 
ATOM   5017  N N   . GLN B 1 11  ? 125.064 140.426 80.674  1.00 62.33  ? 11   GLN B N   1 
ATOM   5018  C CA  . GLN B 1 11  ? 125.924 139.326 80.261  1.00 62.33  ? 11   GLN B CA  1 
ATOM   5019  C C   . GLN B 1 11  ? 125.134 138.028 80.161  1.00 62.33  ? 11   GLN B C   1 
ATOM   5020  O O   . GLN B 1 11  ? 124.797 137.414 81.173  1.00 62.33  ? 11   GLN B O   1 
ATOM   5021  C CB  . GLN B 1 11  ? 127.092 139.160 81.237  1.00 62.33  ? 11   GLN B CB  1 
ATOM   5022  C CG  . GLN B 1 11  ? 128.131 140.276 81.194  1.00 62.33  ? 11   GLN B CG  1 
ATOM   5023  C CD  . GLN B 1 11  ? 128.924 140.313 79.898  1.00 62.33  ? 11   GLN B CD  1 
ATOM   5024  O OE1 . GLN B 1 11  ? 128.482 140.873 78.894  1.00 62.33  ? 11   GLN B OE1 1 
ATOM   5025  N NE2 . GLN B 1 11  ? 130.110 139.719 79.921  1.00 62.33  ? 11   GLN B NE2 1 
ATOM   5026  N N   . LEU B 1 12  ? 124.830 137.622 78.927  1.00 56.31  ? 12   LEU B N   1 
ATOM   5027  C CA  . LEU B 1 12  ? 124.161 136.342 78.719  1.00 56.31  ? 12   LEU B CA  1 
ATOM   5028  C C   . LEU B 1 12  ? 125.129 135.183 78.921  1.00 56.31  ? 12   LEU B C   1 
ATOM   5029  O O   . LEU B 1 12  ? 124.755 134.141 79.471  1.00 56.31  ? 12   LEU B O   1 
ATOM   5030  C CB  . LEU B 1 12  ? 123.514 136.296 77.327  1.00 56.31  ? 12   LEU B CB  1 
ATOM   5031  C CG  . LEU B 1 12  ? 124.295 136.173 76.009  1.00 56.31  ? 12   LEU B CG  1 
ATOM   5032  C CD1 . LEU B 1 12  ? 123.370 135.688 74.908  1.00 56.31  ? 12   LEU B CD1 1 
ATOM   5033  C CD2 . LEU B 1 12  ? 124.956 137.483 75.592  1.00 56.31  ? 12   LEU B CD2 1 
ATOM   5034  N N   . VAL B 1 13  ? 126.375 135.350 78.491  1.00 58.94  ? 13   VAL B N   1 
ATOM   5035  C CA  . VAL B 1 13  ? 127.440 134.385 78.740  1.00 58.94  ? 13   VAL B CA  1 
ATOM   5036  C C   . VAL B 1 13  ? 128.544 135.126 79.487  1.00 58.94  ? 13   VAL B C   1 
ATOM   5037  O O   . VAL B 1 13  ? 128.666 136.351 79.338  1.00 58.94  ? 13   VAL B O   1 
ATOM   5038  C CB  . VAL B 1 13  ? 127.950 133.757 77.432  1.00 58.94  ? 13   VAL B CB  1 
ATOM   5039  C CG1 . VAL B 1 13  ? 126.938 132.757 76.900  1.00 58.94  ? 13   VAL B CG1 1 
ATOM   5040  C CG2 . VAL B 1 13  ? 128.241 134.834 76.393  1.00 58.94  ? 13   VAL B CG2 1 
ATOM   5041  N N   . PRO B 1 14  ? 129.337 134.449 80.323  1.00 61.54  ? 14   PRO B N   1 
ATOM   5042  C CA  . PRO B 1 14  ? 130.466 135.129 80.971  1.00 61.54  ? 14   PRO B CA  1 
ATOM   5043  C C   . PRO B 1 14  ? 131.546 135.513 79.973  1.00 61.54  ? 14   PRO B C   1 
ATOM   5044  O O   . PRO B 1 14  ? 132.231 134.646 79.421  1.00 61.54  ? 14   PRO B O   1 
ATOM   5045  C CB  . PRO B 1 14  ? 130.970 134.090 81.982  1.00 61.54  ? 14   PRO B CB  1 
ATOM   5046  C CG  . PRO B 1 14  ? 129.804 133.180 82.206  1.00 61.54  ? 14   PRO B CG  1 
ATOM   5047  C CD  . PRO B 1 14  ? 129.112 133.106 80.885  1.00 61.54  ? 14   PRO B CD  1 
ATOM   5048  N N   . GLU B 1 15  ? 131.700 136.812 79.729  1.00 57.83  ? 15   GLU B N   1 
ATOM   5049  C CA  . GLU B 1 15  ? 132.632 137.323 78.727  1.00 57.83  ? 15   GLU B CA  1 
ATOM   5050  C C   . GLU B 1 15  ? 133.587 138.307 79.397  1.00 57.83  ? 15   GLU B C   1 
ATOM   5051  O O   . GLU B 1 15  ? 133.361 139.520 79.408  1.00 57.83  ? 15   GLU B O   1 
ATOM   5052  C CB  . GLU B 1 15  ? 131.874 137.964 77.548  1.00 57.83  ? 15   GLU B CB  1 
ATOM   5053  C CG  . GLU B 1 15  ? 132.754 138.471 76.405  1.00 57.83  ? 15   GLU B CG  1 
ATOM   5054  C CD  . GLU B 1 15  ? 133.864 137.509 76.038  1.00 57.83  ? 15   GLU B CD  1 
ATOM   5055  O OE1 . GLU B 1 15  ? 133.565 136.343 75.706  1.00 57.83  ? 15   GLU B OE1 1 
ATOM   5056  O OE2 . GLU B 1 15  ? 135.042 137.922 76.080  1.00 57.83  ? 15   GLU B OE2 1 
ATOM   5057  N N   . TRP B 1 16  ? 134.639 137.764 80.002  1.00 56.75  ? 16   TRP B N   1 
ATOM   5058  C CA  . TRP B 1 16  ? 135.893 138.485 80.222  1.00 56.75  ? 16   TRP B CA  1 
ATOM   5059  C C   . TRP B 1 16  ? 136.971 137.411 80.042  1.00 56.75  ? 16   TRP B C   1 
ATOM   5060  O O   . TRP B 1 16  ? 137.310 136.658 80.958  1.00 56.75  ? 16   TRP B O   1 
ATOM   5061  C CB  . TRP B 1 16  ? 135.947 139.218 81.573  1.00 56.75  ? 16   TRP B CB  1 
ATOM   5062  C CG  . TRP B 1 16  ? 135.900 138.403 82.863  1.00 56.75  ? 16   TRP B CG  1 
ATOM   5063  C CD1 . TRP B 1 16  ? 136.941 138.183 83.718  1.00 56.75  ? 16   TRP B CD1 1 
ATOM   5064  C CD2 . TRP B 1 16  ? 134.773 137.711 83.424  1.00 56.75  ? 16   TRP B CD2 1 
ATOM   5065  N NE1 . TRP B 1 16  ? 136.539 137.403 84.770  1.00 56.75  ? 16   TRP B NE1 1 
ATOM   5066  C CE2 . TRP B 1 16  ? 135.212 137.100 84.616  1.00 56.75  ? 16   TRP B CE2 1 
ATOM   5067  C CE3 . TRP B 1 16  ? 133.439 137.550 83.037  1.00 56.75  ? 16   TRP B CE3 1 
ATOM   5068  C CZ2 . TRP B 1 16  ? 134.366 136.342 85.422  1.00 56.75  ? 16   TRP B CZ2 1 
ATOM   5069  C CZ3 . TRP B 1 16  ? 132.601 136.798 83.840  1.00 56.75  ? 16   TRP B CZ3 1 
ATOM   5070  C CH2 . TRP B 1 16  ? 133.067 136.205 85.017  1.00 56.75  ? 16   TRP B CH2 1 
ATOM   5071  N N   . LYS B 1 17  ? 137.480 137.294 78.820  1.00 59.48  ? 17   LYS B N   1 
ATOM   5072  C CA  . LYS B 1 17  ? 138.339 136.146 78.568  1.00 59.48  ? 17   LYS B CA  1 
ATOM   5073  C C   . LYS B 1 17  ? 139.811 136.530 78.522  1.00 59.48  ? 17   LYS B C   1 
ATOM   5074  O O   . LYS B 1 17  ? 140.626 135.949 79.245  1.00 59.48  ? 17   LYS B O   1 
ATOM   5075  C CB  . LYS B 1 17  ? 137.900 135.435 77.285  1.00 59.48  ? 17   LYS B CB  1 
ATOM   5076  C CG  . LYS B 1 17  ? 136.561 134.686 77.416  1.00 59.48  ? 17   LYS B CG  1 
ATOM   5077  C CD  . LYS B 1 17  ? 136.353 134.034 78.796  1.00 59.48  ? 17   LYS B CD  1 
ATOM   5078  C CE  . LYS B 1 17  ? 137.120 132.720 78.958  1.00 59.48  ? 17   LYS B CE  1 
ATOM   5079  N NZ  . LYS B 1 17  ? 137.169 132.293 80.384  1.00 59.48  ? 17   LYS B NZ  1 
ATOM   5080  N N   . ASP B 1 18  ? 140.169 137.502 77.691  1.00 62.75  ? 18   ASP B N   1 
ATOM   5081  C CA  . ASP B 1 18  ? 141.477 138.113 77.853  1.00 62.75  ? 18   ASP B CA  1 
ATOM   5082  C C   . ASP B 1 18  ? 141.528 139.004 79.083  1.00 62.75  ? 18   ASP B C   1 
ATOM   5083  O O   . ASP B 1 18  ? 142.607 139.186 79.655  1.00 62.75  ? 18   ASP B O   1 
ATOM   5084  C CB  . ASP B 1 18  ? 141.852 138.921 76.610  1.00 62.75  ? 18   ASP B CB  1 
ATOM   5085  C CG  . ASP B 1 18  ? 143.351 139.035 76.423  1.00 62.75  ? 18   ASP B CG  1 
ATOM   5086  O OD1 . ASP B 1 18  ? 143.785 139.668 75.439  1.00 62.75  ? 18   ASP B OD1 1 
ATOM   5087  O OD2 . ASP B 1 18  ? 144.098 138.477 77.254  1.00 62.75  ? 18   ASP B OD2 1 
ATOM   5088  N N   . ALA B 1 19  ? 140.379 139.524 79.521  1.00 53.26  ? 19   ALA B N   1 
ATOM   5089  C CA  . ALA B 1 19  ? 140.273 140.365 80.703  1.00 53.26  ? 19   ALA B CA  1 
ATOM   5090  C C   . ALA B 1 19  ? 140.026 139.562 81.975  1.00 53.26  ? 19   ALA B C   1 
ATOM   5091  O O   . ALA B 1 19  ? 139.531 140.113 82.960  1.00 53.26  ? 19   ALA B O   1 
ATOM   5092  C CB  . ALA B 1 19  ? 139.163 141.401 80.509  1.00 53.26  ? 19   ALA B CB  1 
ATOM   5093  N N   . PHE B 1 20  ? 140.368 138.283 81.979  1.00 60.05  ? 20   PHE B N   1 
ATOM   5094  C CA  . PHE B 1 20  ? 140.323 137.479 83.190  1.00 60.05  ? 20   PHE B CA  1 
ATOM   5095  C C   . PHE B 1 20  ? 141.620 137.749 83.959  1.00 60.05  ? 20   PHE B C   1 
ATOM   5096  O O   . PHE B 1 20  ? 142.484 138.517 83.518  1.00 60.05  ? 20   PHE B O   1 
ATOM   5097  C CB  . PHE B 1 20  ? 140.043 136.022 82.791  1.00 60.05  ? 20   PHE B CB  1 
ATOM   5098  C CG  . PHE B 1 20  ? 139.870 135.048 83.945  1.00 60.05  ? 20   PHE B CG  1 
ATOM   5099  C CD1 . PHE B 1 20  ? 138.609 134.778 84.450  1.00 60.05  ? 20   PHE B CD1 1 
ATOM   5100  C CD2 . PHE B 1 20  ? 140.936 134.272 84.391  1.00 60.05  ? 20   PHE B CD2 1 
ATOM   5101  C CE1 . PHE B 1 20  ? 138.436 133.863 85.480  1.00 60.05  ? 20   PHE B CE1 1 
ATOM   5102  C CE2 . PHE B 1 20  ? 140.773 133.354 85.417  1.00 60.05  ? 20   PHE B CE2 1 
ATOM   5103  C CZ  . PHE B 1 20  ? 139.520 133.143 85.955  1.00 60.05  ? 20   PHE B CZ  1 
ATOM   5104  N N   . VAL B 1 21  ? 141.696 137.214 85.181  1.00 64.19  ? 21   VAL B N   1 
ATOM   5105  C CA  . VAL B 1 21  ? 142.932 137.108 85.948  1.00 64.19  ? 21   VAL B CA  1 
ATOM   5106  C C   . VAL B 1 21  ? 144.045 136.551 85.075  1.00 64.19  ? 21   VAL B C   1 
ATOM   5107  O O   . VAL B 1 21  ? 143.878 135.527 84.404  1.00 64.19  ? 21   VAL B O   1 
ATOM   5108  C CB  . VAL B 1 21  ? 142.690 136.210 87.176  1.00 64.19  ? 21   VAL B CB  1 
ATOM   5109  C CG1 . VAL B 1 21  ? 143.967 135.987 87.966  1.00 64.19  ? 21   VAL B CG1 1 
ATOM   5110  C CG2 . VAL B 1 21  ? 141.587 136.784 88.040  1.00 64.19  ? 21   VAL B CG2 1 
ATOM   5111  N N   . ASP B 1 22  ? 145.187 137.230 85.075  1.00 70.83  ? 22   ASP B N   1 
ATOM   5112  C CA  . ASP B 1 22  ? 146.287 136.812 84.223  1.00 70.83  ? 22   ASP B CA  1 
ATOM   5113  C C   . ASP B 1 22  ? 147.406 136.271 85.097  1.00 70.83  ? 22   ASP B C   1 
ATOM   5114  O O   . ASP B 1 22  ? 148.581 136.609 84.914  1.00 70.83  ? 22   ASP B O   1 
ATOM   5115  C CB  . ASP B 1 22  ? 146.778 137.961 83.348  1.00 70.83  ? 22   ASP B CB  1 
ATOM   5116  C CG  . ASP B 1 22  ? 147.381 137.475 82.050  1.00 70.83  ? 22   ASP B CG  1 
ATOM   5117  O OD1 . ASP B 1 22  ? 147.168 136.291 81.714  1.00 70.83  ? 22   ASP B OD1 1 
ATOM   5118  O OD2 . ASP B 1 22  ? 148.064 138.264 81.365  1.00 70.83  ? 22   ASP B OD2 1 
ATOM   5119  N N   . TYR B 1 23  ? 147.028 135.426 86.062  1.00 73.23  ? 23   TYR B N   1 
ATOM   5120  C CA  . TYR B 1 23  ? 147.989 134.781 86.947  1.00 73.23  ? 23   TYR B CA  1 
ATOM   5121  C C   . TYR B 1 23  ? 148.858 133.766 86.214  1.00 73.23  ? 23   TYR B C   1 
ATOM   5122  O O   . TYR B 1 23  ? 149.852 133.307 86.779  1.00 73.23  ? 23   TYR B O   1 
ATOM   5123  C CB  . TYR B 1 23  ? 147.248 134.129 88.129  1.00 73.23  ? 23   TYR B CB  1 
ATOM   5124  C CG  . TYR B 1 23  ? 146.579 132.777 87.877  1.00 73.23  ? 23   TYR B CG  1 
ATOM   5125  C CD1 . TYR B 1 23  ? 145.233 132.700 87.534  1.00 73.23  ? 23   TYR B CD1 1 
ATOM   5126  C CD2 . TYR B 1 23  ? 147.261 131.576 88.099  1.00 73.23  ? 23   TYR B CD2 1 
ATOM   5127  C CE1 . TYR B 1 23  ? 144.612 131.481 87.329  1.00 73.23  ? 23   TYR B CE1 1 
ATOM   5128  C CE2 . TYR B 1 23  ? 146.647 130.354 87.895  1.00 73.23  ? 23   TYR B CE2 1 
ATOM   5129  C CZ  . TYR B 1 23  ? 145.323 130.314 87.516  1.00 73.23  ? 23   TYR B CZ  1 
ATOM   5130  O OH  . TYR B 1 23  ? 144.709 129.099 87.323  1.00 73.23  ? 23   TYR B OH  1 
ATOM   5131  N N   . SER B 1 24  ? 148.478 133.369 85.001  1.00 69.97  ? 24   SER B N   1 
ATOM   5132  C CA  . SER B 1 24  ? 149.295 132.498 84.168  1.00 69.97  ? 24   SER B CA  1 
ATOM   5133  C C   . SER B 1 24  ? 150.427 133.264 83.494  1.00 69.97  ? 24   SER B C   1 
ATOM   5134  O O   . SER B 1 24  ? 151.601 132.907 83.643  1.00 69.97  ? 24   SER B O   1 
ATOM   5135  C CB  . SER B 1 24  ? 148.424 131.815 83.112  1.00 69.97  ? 24   SER B CB  1 
ATOM   5136  O OG  . SER B 1 24  ? 147.885 132.767 82.212  1.00 69.97  ? 24   SER B OG  1 
ATOM   5137  N N   . GLN B 1 25  ? 150.081 134.324 82.755  1.00 70.40  ? 25   GLN B N   1 
ATOM   5138  C CA  . GLN B 1 25  ? 151.032 134.928 81.827  1.00 70.40  ? 25   GLN B CA  1 
ATOM   5139  C C   . GLN B 1 25  ? 152.082 135.771 82.537  1.00 70.40  ? 25   GLN B C   1 
ATOM   5140  O O   . GLN B 1 25  ? 153.228 135.841 82.077  1.00 70.40  ? 25   GLN B O   1 
ATOM   5141  C CB  . GLN B 1 25  ? 150.291 135.782 80.796  1.00 70.40  ? 25   GLN B CB  1 
ATOM   5142  C CG  . GLN B 1 25  ? 151.022 135.964 79.466  1.00 70.40  ? 25   GLN B CG  1 
ATOM   5143  C CD  . GLN B 1 25  ? 151.978 137.144 79.463  1.00 70.40  ? 25   GLN B CD  1 
ATOM   5144  O OE1 . GLN B 1 25  ? 151.571 138.290 79.651  1.00 70.40  ? 25   GLN B OE1 1 
ATOM   5145  N NE2 . GLN B 1 25  ? 153.259 136.866 79.248  1.00 70.40  ? 25   GLN B NE2 1 
ATOM   5146  N N   . LEU B 1 26  ? 151.724 136.408 83.652  1.00 69.85  ? 26   LEU B N   1 
ATOM   5147  C CA  . LEU B 1 26  ? 152.621 137.390 84.253  1.00 69.85  ? 26   LEU B CA  1 
ATOM   5148  C C   . LEU B 1 26  ? 153.760 136.717 85.012  1.00 69.85  ? 26   LEU B C   1 
ATOM   5149  O O   . LEU B 1 26  ? 154.876 137.245 85.071  1.00 69.85  ? 26   LEU B O   1 
ATOM   5150  C CB  . LEU B 1 26  ? 151.834 138.335 85.163  1.00 69.85  ? 26   LEU B CB  1 
ATOM   5151  C CG  . LEU B 1 26  ? 151.356 139.684 84.601  1.00 69.85  ? 26   LEU B CG  1 
ATOM   5152  C CD1 . LEU B 1 26  ? 150.782 139.585 83.190  1.00 69.85  ? 26   LEU B CD1 1 
ATOM   5153  C CD2 . LEU B 1 26  ? 150.345 140.322 85.541  1.00 69.85  ? 26   LEU B CD2 1 
ATOM   5154  N N   . LYS B 1 27  ? 153.504 135.543 85.593  1.00 75.50  ? 27   LYS B N   1 
ATOM   5155  C CA  . LYS B 1 27  ? 154.532 134.904 86.404  1.00 75.50  ? 27   LYS B CA  1 
ATOM   5156  C C   . LYS B 1 27  ? 155.588 134.196 85.568  1.00 75.50  ? 27   LYS B C   1 
ATOM   5157  O O   . LYS B 1 27  ? 156.704 133.995 86.055  1.00 75.50  ? 27   LYS B O   1 
ATOM   5158  C CB  . LYS B 1 27  ? 153.916 133.898 87.376  1.00 75.50  ? 27   LYS B CB  1 
ATOM   5159  C CG  . LYS B 1 27  ? 153.036 132.861 86.724  1.00 75.50  ? 27   LYS B CG  1 
ATOM   5160  C CD  . LYS B 1 27  ? 152.673 131.749 87.701  1.00 75.50  ? 27   LYS B CD  1 
ATOM   5161  C CE  . LYS B 1 27  ? 153.906 131.119 88.332  1.00 75.50  ? 27   LYS B CE  1 
ATOM   5162  N NZ  . LYS B 1 27  ? 153.549 129.996 89.243  1.00 75.50  ? 27   LYS B NZ  1 
ATOM   5163  N N   . LYS B 1 28  ? 155.270 133.798 84.334  1.00 68.13  ? 28   LYS B N   1 
ATOM   5164  C CA  . LYS B 1 28  ? 156.308 133.190 83.512  1.00 68.13  ? 28   LYS B CA  1 
ATOM   5165  C C   . LYS B 1 28  ? 157.224 134.251 82.917  1.00 68.13  ? 28   LYS B C   1 
ATOM   5166  O O   . LYS B 1 28  ? 158.367 133.951 82.553  1.00 68.13  ? 28   LYS B O   1 
ATOM   5167  C CB  . LYS B 1 28  ? 155.698 132.302 82.424  1.00 68.13  ? 28   LYS B CB  1 
ATOM   5168  C CG  . LYS B 1 28  ? 155.108 133.009 81.218  1.00 68.13  ? 28   LYS B CG  1 
ATOM   5169  C CD  . LYS B 1 28  ? 153.866 132.280 80.731  1.00 68.13  ? 28   LYS B CD  1 
ATOM   5170  C CE  . LYS B 1 28  ? 153.215 132.992 79.561  1.00 68.13  ? 28   LYS B CE  1 
ATOM   5171  N NZ  . LYS B 1 28  ? 151.847 132.465 79.301  1.00 68.13  ? 28   LYS B NZ  1 
ATOM   5172  N N   . ASP B 1 29  ? 156.746 135.494 82.818  1.00 68.08  ? 29   ASP B N   1 
ATOM   5173  C CA  . ASP B 1 29  ? 157.652 136.617 82.625  1.00 68.08  ? 29   ASP B CA  1 
ATOM   5174  C C   . ASP B 1 29  ? 158.435 136.913 83.893  1.00 68.08  ? 29   ASP B C   1 
ATOM   5175  O O   . ASP B 1 29  ? 159.588 137.347 83.811  1.00 68.08  ? 29   ASP B O   1 
ATOM   5176  C CB  . ASP B 1 29  ? 156.874 137.852 82.181  1.00 68.08  ? 29   ASP B CB  1 
ATOM   5177  C CG  . ASP B 1 29  ? 155.854 137.535 81.114  1.00 68.08  ? 29   ASP B CG  1 
ATOM   5178  O OD1 . ASP B 1 29  ? 156.103 136.608 80.316  1.00 68.08  ? 29   ASP B OD1 1 
ATOM   5179  O OD2 . ASP B 1 29  ? 154.804 138.209 81.071  1.00 68.08  ? 29   ASP B OD2 1 
ATOM   5180  N N   . LEU B 1 30  ? 157.835 136.675 85.063  1.00 67.93  ? 30   LEU B N   1 
ATOM   5181  C CA  . LEU B 1 30  ? 158.597 136.722 86.305  1.00 67.93  ? 30   LEU B CA  1 
ATOM   5182  C C   . LEU B 1 30  ? 159.502 135.501 86.431  1.00 67.93  ? 30   LEU B C   1 
ATOM   5183  O O   . LEU B 1 30  ? 160.504 135.544 87.153  1.00 67.93  ? 30   LEU B O   1 
ATOM   5184  C CB  . LEU B 1 30  ? 157.644 136.847 87.499  1.00 67.93  ? 30   LEU B CB  1 
ATOM   5185  C CG  . LEU B 1 30  ? 158.170 137.315 88.864  1.00 67.93  ? 30   LEU B CG  1 
ATOM   5186  C CD1 . LEU B 1 30  ? 157.101 138.142 89.563  1.00 67.93  ? 30   LEU B CD1 1 
ATOM   5187  C CD2 . LEU B 1 30  ? 158.579 136.153 89.762  1.00 67.93  ? 30   LEU B CD2 1 
ATOM   5188  N N   . LYS B 1 31  ? 159.179 134.407 85.735  1.00 80.90  ? 31   LYS B N   1 
ATOM   5189  C CA  . LYS B 1 31  ? 160.171 133.355 85.545  1.00 80.90  ? 31   LYS B CA  1 
ATOM   5190  C C   . LYS B 1 31  ? 161.258 133.784 84.566  1.00 80.90  ? 31   LYS B C   1 
ATOM   5191  O O   . LYS B 1 31  ? 162.350 133.207 84.577  1.00 80.90  ? 31   LYS B O   1 
ATOM   5192  C CB  . LYS B 1 31  ? 159.518 132.068 85.025  1.00 80.90  ? 31   LYS B CB  1 
ATOM   5193  C CG  . LYS B 1 31  ? 160.244 130.761 85.388  1.00 80.90  ? 31   LYS B CG  1 
ATOM   5194  C CD  . LYS B 1 31  ? 160.243 130.422 86.881  1.00 80.90  ? 31   LYS B CD  1 
ATOM   5195  C CE  . LYS B 1 31  ? 158.843 130.035 87.422  1.00 80.90  ? 31   LYS B CE  1 
ATOM   5196  N NZ  . LYS B 1 31  ? 158.990 129.701 88.891  1.00 80.90  ? 31   LYS B NZ  1 
ATOM   5197  N N   . LYS B 1 32  ? 160.982 134.770 83.709  1.00 67.30  ? 32   LYS B N   1 
ATOM   5198  C CA  . LYS B 1 32  ? 161.961 135.175 82.709  1.00 67.30  ? 32   LYS B CA  1 
ATOM   5199  C C   . LYS B 1 32  ? 162.937 136.226 83.227  1.00 67.30  ? 32   LYS B C   1 
ATOM   5200  O O   . LYS B 1 32  ? 164.041 136.345 82.687  1.00 67.30  ? 32   LYS B O   1 
ATOM   5201  C CB  . LYS B 1 32  ? 161.253 135.680 81.449  1.00 67.30  ? 32   LYS B CB  1 
ATOM   5202  C CG  . LYS B 1 32  ? 162.087 135.532 80.178  1.00 67.30  ? 32   LYS B CG  1 
ATOM   5203  C CD  . LYS B 1 32  ? 161.239 135.327 78.927  1.00 67.30  ? 32   LYS B CD  1 
ATOM   5204  C CE  . LYS B 1 32  ? 160.022 136.240 78.889  1.00 67.30  ? 32   LYS B CE  1 
ATOM   5205  N NZ  . LYS B 1 32  ? 159.450 136.327 77.518  1.00 67.30  ? 32   LYS B NZ  1 
ATOM   5206  N N   . ILE B 1 33  ? 162.570 136.988 84.256  1.00 68.93  ? 33   ILE B N   1 
ATOM   5207  C CA  . ILE B 1 33  ? 163.579 137.808 84.918  1.00 68.93  ? 33   ILE B CA  1 
ATOM   5208  C C   . ILE B 1 33  ? 164.436 136.925 85.830  1.00 68.93  ? 33   ILE B C   1 
ATOM   5209  O O   . ILE B 1 33  ? 165.601 137.242 86.106  1.00 68.93  ? 33   ILE B O   1 
ATOM   5210  C CB  . ILE B 1 33  ? 162.902 138.985 85.657  1.00 68.93  ? 33   ILE B CB  1 
ATOM   5211  C CG1 . ILE B 1 33  ? 163.924 139.944 86.285  1.00 68.93  ? 33   ILE B CG1 1 
ATOM   5212  C CG2 . ILE B 1 33  ? 161.926 138.488 86.711  1.00 68.93  ? 33   ILE B CG2 1 
ATOM   5213  C CD1 . ILE B 1 33  ? 163.425 141.366 86.433  1.00 68.93  ? 33   ILE B CD1 1 
ATOM   5214  N N   . HIS B 1 34  ? 163.892 135.779 86.255  1.00 68.30  ? 34   HIS B N   1 
ATOM   5215  C CA  . HIS B 1 34  ? 164.622 134.803 87.056  1.00 68.30  ? 34   HIS B CA  1 
ATOM   5216  C C   . HIS B 1 34  ? 165.787 134.182 86.290  1.00 68.30  ? 34   HIS B C   1 
ATOM   5217  O O   . HIS B 1 34  ? 166.841 133.921 86.881  1.00 68.30  ? 34   HIS B O   1 
ATOM   5218  C CB  . HIS B 1 34  ? 163.654 133.716 87.528  1.00 68.30  ? 34   HIS B CB  1 
ATOM   5219  C CG  . HIS B 1 34  ? 164.165 132.882 88.661  1.00 68.30  ? 34   HIS B CG  1 
ATOM   5220  N ND1 . HIS B 1 34  ? 163.466 131.803 89.158  1.00 68.30  ? 34   HIS B ND1 1 
ATOM   5221  C CD2 . HIS B 1 34  ? 165.291 132.976 89.407  1.00 68.30  ? 34   HIS B CD2 1 
ATOM   5222  C CE1 . HIS B 1 34  ? 164.145 131.260 90.152  1.00 68.30  ? 34   HIS B CE1 1 
ATOM   5223  N NE2 . HIS B 1 34  ? 165.257 131.953 90.324  1.00 68.30  ? 34   HIS B NE2 1 
ATOM   5224  N N   . LEU B 1 35  ? 165.632 133.959 84.980  1.00 66.39  ? 35   LEU B N   1 
ATOM   5225  C CA  . LEU B 1 35  ? 166.741 133.428 84.191  1.00 66.39  ? 35   LEU B CA  1 
ATOM   5226  C C   . LEU B 1 35  ? 167.722 134.523 83.791  1.00 66.39  ? 35   LEU B C   1 
ATOM   5227  O O   . LEU B 1 35  ? 168.803 134.225 83.271  1.00 66.39  ? 35   LEU B O   1 
ATOM   5228  C CB  . LEU B 1 35  ? 166.208 132.688 82.957  1.00 66.39  ? 35   LEU B CB  1 
ATOM   5229  C CG  . LEU B 1 35  ? 165.262 133.374 81.961  1.00 66.39  ? 35   LEU B CG  1 
ATOM   5230  C CD1 . LEU B 1 35  ? 165.999 134.021 80.788  1.00 66.39  ? 35   LEU B CD1 1 
ATOM   5231  C CD2 . LEU B 1 35  ? 164.211 132.394 81.460  1.00 66.39  ? 35   LEU B CD2 1 
ATOM   5232  N N   . PHE B 1 36  ? 167.361 135.787 84.015  1.00 67.67  ? 36   PHE B N   1 
ATOM   5233  C CA  . PHE B 1 36  ? 168.287 136.891 83.803  1.00 67.67  ? 36   PHE B CA  1 
ATOM   5234  C C   . PHE B 1 36  ? 169.159 137.146 85.028  1.00 67.67  ? 36   PHE B C   1 
ATOM   5235  O O   . PHE B 1 36  ? 170.202 137.800 84.911  1.00 67.67  ? 36   PHE B O   1 
ATOM   5236  C CB  . PHE B 1 36  ? 167.497 138.152 83.420  1.00 67.67  ? 36   PHE B CB  1 
ATOM   5237  C CG  . PHE B 1 36  ? 168.357 139.333 83.050  1.00 67.67  ? 36   PHE B CG  1 
ATOM   5238  C CD1 . PHE B 1 36  ? 169.014 139.377 81.828  1.00 67.67  ? 36   PHE B CD1 1 
ATOM   5239  C CD2 . PHE B 1 36  ? 168.505 140.398 83.925  1.00 67.67  ? 36   PHE B CD2 1 
ATOM   5240  C CE1 . PHE B 1 36  ? 169.809 140.464 81.484  1.00 67.67  ? 36   PHE B CE1 1 
ATOM   5241  C CE2 . PHE B 1 36  ? 169.298 141.488 83.591  1.00 67.67  ? 36   PHE B CE2 1 
ATOM   5242  C CZ  . PHE B 1 36  ? 169.949 141.518 82.368  1.00 67.67  ? 36   PHE B CZ  1 
ATOM   5243  N N   . THR B 1 37  ? 168.777 136.603 86.188  1.00 64.78  ? 37   THR B N   1 
ATOM   5244  C CA  . THR B 1 37  ? 169.510 136.851 87.426  1.00 64.78  ? 37   THR B CA  1 
ATOM   5245  C C   . THR B 1 37  ? 170.867 136.158 87.413  1.00 64.78  ? 37   THR B C   1 
ATOM   5246  O O   . THR B 1 37  ? 171.888 136.765 87.757  1.00 64.78  ? 37   THR B O   1 
ATOM   5247  C CB  . THR B 1 37  ? 168.679 136.379 88.623  1.00 64.78  ? 37   THR B CB  1 
ATOM   5248  O OG1 . THR B 1 37  ? 167.402 137.025 88.602  1.00 64.78  ? 37   THR B OG1 1 
ATOM   5249  C CG2 . THR B 1 37  ? 169.378 136.715 89.932  1.00 64.78  ? 37   THR B CG2 1 
ATOM   5250  N N   . ASN B 1 38  ? 170.900 134.894 86.992  1.00 64.73  ? 38   ASN B N   1 
ATOM   5251  C CA  . ASN B 1 38  ? 172.170 134.187 86.895  1.00 64.73  ? 38   ASN B CA  1 
ATOM   5252  C C   . ASN B 1 38  ? 172.836 134.419 85.545  1.00 64.73  ? 38   ASN B C   1 
ATOM   5253  O O   . ASN B 1 38  ? 174.043 134.189 85.405  1.00 64.73  ? 38   ASN B O   1 
ATOM   5254  C CB  . ASN B 1 38  ? 171.993 132.683 87.144  1.00 64.73  ? 38   ASN B CB  1 
ATOM   5255  C CG  . ASN B 1 38  ? 171.679 132.334 88.600  1.00 64.73  ? 38   ASN B CG  1 
ATOM   5256  O OD1 . ASN B 1 38  ? 171.978 133.081 89.530  1.00 64.73  ? 38   ASN B OD1 1 
ATOM   5257  N ND2 . ASN B 1 38  ? 171.075 131.168 88.792  1.00 64.73  ? 38   ASN B ND2 1 
ATOM   5258  N N   . GLY B 1 39  ? 172.078 134.862 84.548  1.00 55.36  ? 39   GLY B N   1 
ATOM   5259  C CA  . GLY B 1 39  ? 172.620 135.104 83.224  1.00 55.36  ? 39   GLY B CA  1 
ATOM   5260  C C   . GLY B 1 39  ? 173.396 136.401 83.111  1.00 55.36  ? 39   GLY B C   1 
ATOM   5261  O O   . GLY B 1 39  ? 174.374 136.617 83.827  1.00 55.36  ? 39   GLY B O   1 
ATOM   5262  N N   . VAL B 1 73  ? 160.551 149.872 94.527  1.00 63.76  ? 73   VAL B N   1 
ATOM   5263  C CA  . VAL B 1 73  ? 161.279 149.519 93.318  1.00 63.76  ? 73   VAL B CA  1 
ATOM   5264  C C   . VAL B 1 73  ? 160.868 150.507 92.217  1.00 63.76  ? 73   VAL B C   1 
ATOM   5265  O O   . VAL B 1 73  ? 161.593 150.725 91.245  1.00 63.76  ? 73   VAL B O   1 
ATOM   5266  C CB  . VAL B 1 73  ? 161.024 148.031 92.928  1.00 63.76  ? 73   VAL B CB  1 
ATOM   5267  C CG1 . VAL B 1 73  ? 159.549 147.776 92.632  1.00 63.76  ? 73   VAL B CG1 1 
ATOM   5268  C CG2 . VAL B 1 73  ? 161.936 147.562 91.788  1.00 63.76  ? 73   VAL B CG2 1 
ATOM   5269  N N   . ILE B 1 74  ? 159.707 151.133 92.396  1.00 63.81  ? 74   ILE B N   1 
ATOM   5270  C CA  . ILE B 1 74  ? 159.199 152.086 91.417  1.00 63.81  ? 74   ILE B CA  1 
ATOM   5271  C C   . ILE B 1 74  ? 158.433 153.198 92.128  1.00 63.81  ? 74   ILE B C   1 
ATOM   5272  O O   . ILE B 1 74  ? 157.687 152.944 93.081  1.00 63.81  ? 74   ILE B O   1 
ATOM   5273  C CB  . ILE B 1 74  ? 158.326 151.364 90.362  1.00 63.81  ? 74   ILE B CB  1 
ATOM   5274  C CG1 . ILE B 1 74  ? 157.667 152.358 89.393  1.00 63.81  ? 74   ILE B CG1 1 
ATOM   5275  C CG2 . ILE B 1 74  ? 157.306 150.435 91.026  1.00 63.81  ? 74   ILE B CG2 1 
ATOM   5276  C CD1 . ILE B 1 74  ? 156.868 151.738 88.285  1.00 63.81  ? 74   ILE B CD1 1 
ATOM   5277  N N   . GLN B 1 75  ? 158.631 154.443 91.694  1.00 65.38  ? 75   GLN B N   1 
ATOM   5278  C CA  . GLN B 1 75  ? 157.668 155.499 91.975  1.00 65.38  ? 75   GLN B CA  1 
ATOM   5279  C C   . GLN B 1 75  ? 156.785 155.633 90.740  1.00 65.38  ? 75   GLN B C   1 
ATOM   5280  O O   . GLN B 1 75  ? 157.278 155.624 89.606  1.00 65.38  ? 75   GLN B O   1 
ATOM   5281  C CB  . GLN B 1 75  ? 158.354 156.821 92.379  1.00 65.38  ? 75   GLN B CB  1 
ATOM   5282  C CG  . GLN B 1 75  ? 158.965 157.700 91.289  1.00 65.38  ? 75   GLN B CG  1 
ATOM   5283  C CD  . GLN B 1 75  ? 159.626 158.947 91.849  1.00 65.38  ? 75   GLN B CD  1 
ATOM   5284  O OE1 . GLN B 1 75  ? 159.265 159.427 92.923  1.00 65.38  ? 75   GLN B OE1 1 
ATOM   5285  N NE2 . GLN B 1 75  ? 160.600 159.478 91.119  1.00 65.38  ? 75   GLN B NE2 1 
ATOM   5286  N N   . VAL B 1 76  ? 155.473 155.655 90.956  1.00 66.65  ? 76   VAL B N   1 
ATOM   5287  C CA  . VAL B 1 76  ? 154.527 155.525 89.851  1.00 66.65  ? 76   VAL B CA  1 
ATOM   5288  C C   . VAL B 1 76  ? 154.212 156.914 89.307  1.00 66.65  ? 76   VAL B C   1 
ATOM   5289  O O   . VAL B 1 76  ? 153.751 157.791 90.043  1.00 66.65  ? 76   VAL B O   1 
ATOM   5290  C CB  . VAL B 1 76  ? 153.252 154.794 90.282  1.00 66.65  ? 76   VAL B CB  1 
ATOM   5291  C CG1 . VAL B 1 76  ? 152.410 154.465 89.060  1.00 66.65  ? 76   VAL B CG1 1 
ATOM   5292  C CG2 . VAL B 1 76  ? 153.598 153.531 91.058  1.00 66.65  ? 76   VAL B CG2 1 
ATOM   5293  N N   . HIS B 1 77  ? 154.464 157.115 88.016  1.00 68.98  ? 77   HIS B N   1 
ATOM   5294  C CA  . HIS B 1 77  ? 154.117 158.355 87.327  1.00 68.98  ? 77   HIS B CA  1 
ATOM   5295  C C   . HIS B 1 77  ? 152.649 158.280 86.928  1.00 68.98  ? 77   HIS B C   1 
ATOM   5296  O O   . HIS B 1 77  ? 152.298 157.824 85.840  1.00 68.98  ? 77   HIS B O   1 
ATOM   5297  C CB  . HIS B 1 77  ? 155.020 158.567 86.119  1.00 68.98  ? 77   HIS B CB  1 
ATOM   5298  C CG  . HIS B 1 77  ? 156.432 158.911 86.473  1.00 68.98  ? 77   HIS B CG  1 
ATOM   5299  N ND1 . HIS B 1 77  ? 156.934 160.190 86.370  1.00 68.98  ? 77   HIS B ND1 1 
ATOM   5300  C CD2 . HIS B 1 77  ? 157.449 158.144 86.933  1.00 68.98  ? 77   HIS B CD2 1 
ATOM   5301  C CE1 . HIS B 1 77  ? 158.199 160.197 86.750  1.00 68.98  ? 77   HIS B CE1 1 
ATOM   5302  N NE2 . HIS B 1 77  ? 158.536 158.967 87.095  1.00 68.98  ? 77   HIS B NE2 1 
ATOM   5303  N N   . LYS B 1 78  ? 151.784 158.732 87.831  1.00 69.88  ? 78   LYS B N   1 
ATOM   5304  C CA  . LYS B 1 78  ? 150.343 158.671 87.627  1.00 69.88  ? 78   LYS B CA  1 
ATOM   5305  C C   . LYS B 1 78  ? 149.900 159.691 86.587  1.00 69.88  ? 78   LYS B C   1 
ATOM   5306  O O   . LYS B 1 78  ? 149.866 160.895 86.863  1.00 69.88  ? 78   LYS B O   1 
ATOM   5307  C CB  . LYS B 1 78  ? 149.618 158.932 88.947  1.00 69.88  ? 78   LYS B CB  1 
ATOM   5308  C CG  . LYS B 1 78  ? 148.243 158.306 89.065  1.00 69.88  ? 78   LYS B CG  1 
ATOM   5309  C CD  . LYS B 1 78  ? 147.985 157.849 90.489  1.00 69.88  ? 78   LYS B CD  1 
ATOM   5310  C CE  . LYS B 1 78  ? 146.807 156.900 90.567  1.00 69.88  ? 78   LYS B CE  1 
ATOM   5311  N NZ  . LYS B 1 78  ? 146.753 156.241 91.896  1.00 69.88  ? 78   LYS B NZ  1 
ATOM   5312  N N   . LYS B 1 79  ? 149.552 159.213 85.395  1.00 74.64  ? 79   LYS B N   1 
ATOM   5313  C CA  . LYS B 1 79  ? 148.968 160.078 84.380  1.00 74.64  ? 79   LYS B CA  1 
ATOM   5314  C C   . LYS B 1 79  ? 147.720 159.407 83.829  1.00 74.64  ? 79   LYS B C   1 
ATOM   5315  O O   . LYS B 1 79  ? 147.728 158.221 83.488  1.00 74.64  ? 79   LYS B O   1 
ATOM   5316  C CB  . LYS B 1 79  ? 149.940 160.388 83.232  1.00 74.64  ? 79   LYS B CB  1 
ATOM   5317  C CG  . LYS B 1 79  ? 151.317 160.883 83.636  1.00 74.64  ? 79   LYS B CG  1 
ATOM   5318  C CD  . LYS B 1 79  ? 152.264 160.850 82.449  1.00 74.64  ? 79   LYS B CD  1 
ATOM   5319  C CE  . LYS B 1 79  ? 152.628 159.428 82.069  1.00 74.64  ? 79   LYS B CE  1 
ATOM   5320  N NZ  . LYS B 1 79  ? 153.512 159.381 80.874  1.00 74.64  ? 79   LYS B NZ  1 
ATOM   5321  N N   . LEU B 1 80  ? 146.647 160.184 83.749  1.00 75.93  ? 80   LEU B N   1 
ATOM   5322  C CA  . LEU B 1 80  ? 145.417 159.750 83.114  1.00 75.93  ? 80   LEU B CA  1 
ATOM   5323  C C   . LEU B 1 80  ? 145.506 160.033 81.617  1.00 75.93  ? 80   LEU B C   1 
ATOM   5324  O O   . LEU B 1 80  ? 146.541 160.474 81.106  1.00 75.93  ? 80   LEU B O   1 
ATOM   5325  C CB  . LEU B 1 80  ? 144.211 160.433 83.766  1.00 75.93  ? 80   LEU B CB  1 
ATOM   5326  C CG  . LEU B 1 80  ? 143.397 159.599 84.760  1.00 75.93  ? 80   LEU B CG  1 
ATOM   5327  C CD1 . LEU B 1 80  ? 144.242 159.184 85.954  1.00 75.93  ? 80   LEU B CD1 1 
ATOM   5328  C CD2 . LEU B 1 80  ? 142.165 160.364 85.214  1.00 75.93  ? 80   LEU B CD2 1 
ATOM   5329  N N   . ALA B 1 81  ? 144.415 159.781 80.900  1.00 68.06  ? 81   ALA B N   1 
ATOM   5330  C CA  . ALA B 1 81  ? 144.420 159.910 79.450  1.00 68.06  ? 81   ALA B CA  1 
ATOM   5331  C C   . ALA B 1 81  ? 144.394 161.373 79.029  1.00 68.06  ? 81   ALA B C   1 
ATOM   5332  O O   . ALA B 1 81  ? 143.674 162.191 79.608  1.00 68.06  ? 81   ALA B O   1 
ATOM   5333  C CB  . ALA B 1 81  ? 143.226 159.173 78.845  1.00 68.06  ? 81   ALA B CB  1 
ATOM   5334  N N   . SER B 1 82  ? 145.195 161.698 78.015  1.00 65.11  ? 82   SER B N   1 
ATOM   5335  C CA  . SER B 1 82  ? 145.190 163.019 77.401  1.00 65.11  ? 82   SER B CA  1 
ATOM   5336  C C   . SER B 1 82  ? 144.095 163.171 76.355  1.00 65.11  ? 82   SER B C   1 
ATOM   5337  O O   . SER B 1 82  ? 143.965 164.248 75.762  1.00 65.11  ? 82   SER B O   1 
ATOM   5338  C CB  . SER B 1 82  ? 146.551 163.313 76.763  1.00 65.11  ? 82   SER B CB  1 
ATOM   5339  O OG  . SER B 1 82  ? 146.789 162.466 75.652  1.00 65.11  ? 82   SER B OG  1 
ATOM   5340  N N   . SER B 1 83  ? 143.314 162.120 76.111  1.00 70.77  ? 83   SER B N   1 
ATOM   5341  C CA  . SER B 1 83  ? 142.197 162.152 75.181  1.00 70.77  ? 83   SER B CA  1 
ATOM   5342  C C   . SER B 1 83  ? 140.871 162.446 75.873  1.00 70.77  ? 83   SER B C   1 
ATOM   5343  O O   . SER B 1 83  ? 139.813 162.085 75.344  1.00 70.77  ? 83   SER B O   1 
ATOM   5344  C CB  . SER B 1 83  ? 142.108 160.825 74.426  1.00 70.77  ? 83   SER B CB  1 
ATOM   5345  O OG  . SER B 1 83  ? 142.062 159.732 75.329  1.00 70.77  ? 83   SER B OG  1 
ATOM   5346  N N   . GLY B 1 84  ? 140.905 163.084 77.042  1.00 67.24  ? 84   GLY B N   1 
ATOM   5347  C CA  . GLY B 1 84  ? 139.692 163.348 77.787  1.00 67.24  ? 84   GLY B CA  1 
ATOM   5348  C C   . GLY B 1 84  ? 139.057 162.135 78.426  1.00 67.24  ? 84   GLY B C   1 
ATOM   5349  O O   . GLY B 1 84  ? 137.878 162.191 78.789  1.00 67.24  ? 84   GLY B O   1 
ATOM   5350  N N   . SER B 1 85  ? 139.799 161.045 78.580  1.00 69.67  ? 85   SER B N   1 
ATOM   5351  C CA  . SER B 1 85  ? 139.293 159.807 79.154  1.00 69.67  ? 85   SER B CA  1 
ATOM   5352  C C   . SER B 1 85  ? 140.051 159.503 80.446  1.00 69.67  ? 85   SER B C   1 
ATOM   5353  O O   . SER B 1 85  ? 140.846 160.312 80.933  1.00 69.67  ? 85   SER B O   1 
ATOM   5354  C CB  . SER B 1 85  ? 139.407 158.660 78.147  1.00 69.67  ? 85   SER B CB  1 
ATOM   5355  O OG  . SER B 1 85  ? 139.246 157.405 78.785  1.00 69.67  ? 85   SER B OG  1 
ATOM   5356  N N   . ASN B 1 86  ? 139.793 158.323 81.000  1.00 71.33  ? 86   ASN B N   1 
ATOM   5357  C CA  . ASN B 1 86  ? 140.378 157.876 82.256  1.00 71.33  ? 86   ASN B CA  1 
ATOM   5358  C C   . ASN B 1 86  ? 141.209 156.615 82.056  1.00 71.33  ? 86   ASN B C   1 
ATOM   5359  O O   . ASN B 1 86  ? 141.109 155.651 82.819  1.00 71.33  ? 86   ASN B O   1 
ATOM   5360  C CB  . ASN B 1 86  ? 139.292 157.670 83.310  1.00 71.33  ? 86   ASN B CB  1 
ATOM   5361  C CG  . ASN B 1 86  ? 138.156 156.783 82.823  1.00 71.33  ? 86   ASN B CG  1 
ATOM   5362  O OD1 . ASN B 1 86  ? 138.186 156.248 81.713  1.00 71.33  ? 86   ASN B OD1 1 
ATOM   5363  N ND2 . ASN B 1 86  ? 137.139 156.629 83.660  1.00 71.33  ? 86   ASN B ND2 1 
ATOM   5364  N N   . ASN B 1 87  ? 142.033 156.607 81.013  1.00 73.61  ? 87   ASN B N   1 
ATOM   5365  C CA  . ASN B 1 87  ? 142.920 155.484 80.748  1.00 73.61  ? 87   ASN B CA  1 
ATOM   5366  C C   . ASN B 1 87  ? 144.165 155.625 81.614  1.00 73.61  ? 87   ASN B C   1 
ATOM   5367  O O   . ASN B 1 87  ? 144.943 156.570 81.440  1.00 73.61  ? 87   ASN B O   1 
ATOM   5368  C CB  . ASN B 1 87  ? 143.289 155.440 79.268  1.00 73.61  ? 87   ASN B CB  1 
ATOM   5369  C CG  . ASN B 1 87  ? 142.101 155.123 78.382  1.00 73.61  ? 87   ASN B CG  1 
ATOM   5370  O OD1 . ASN B 1 87  ? 141.277 154.271 78.712  1.00 73.61  ? 87   ASN B OD1 1 
ATOM   5371  N ND2 . ASN B 1 87  ? 142.005 155.811 77.250  1.00 73.61  ? 87   ASN B ND2 1 
ATOM   5372  N N   . ASP B 1 88  ? 144.357 154.692 82.541  1.00 66.73  ? 88   ASP B N   1 
ATOM   5373  C CA  . ASP B 1 88  ? 145.435 154.794 83.522  1.00 66.73  ? 88   ASP B CA  1 
ATOM   5374  C C   . ASP B 1 88  ? 146.744 154.340 82.888  1.00 66.73  ? 88   ASP B C   1 
ATOM   5375  O O   . ASP B 1 88  ? 147.200 153.216 83.110  1.00 66.73  ? 88   ASP B O   1 
ATOM   5376  C CB  . ASP B 1 88  ? 145.108 153.970 84.762  1.00 66.73  ? 88   ASP B CB  1 
ATOM   5377  C CG  . ASP B 1 88  ? 143.939 154.531 85.540  1.00 66.73  ? 88   ASP B CG  1 
ATOM   5378  O OD1 . ASP B 1 88  ? 143.908 154.360 86.775  1.00 66.73  ? 88   ASP B OD1 1 
ATOM   5379  O OD2 . ASP B 1 88  ? 143.045 155.134 84.916  1.00 66.73  ? 88   ASP B OD2 1 
ATOM   5380  N N   . VAL B 1 89  ? 147.371 155.228 82.120  1.00 65.14  ? 89   VAL B N   1 
ATOM   5381  C CA  . VAL B 1 89  ? 148.654 154.938 81.477  1.00 65.14  ? 89   VAL B CA  1 
ATOM   5382  C C   . VAL B 1 89  ? 149.746 155.331 82.474  1.00 65.14  ? 89   VAL B C   1 
ATOM   5383  O O   . VAL B 1 89  ? 149.995 156.506 82.742  1.00 65.14  ? 89   VAL B O   1 
ATOM   5384  C CB  . VAL B 1 89  ? 148.791 155.639 80.125  1.00 65.14  ? 89   VAL B CB  1 
ATOM   5385  C CG1 . VAL B 1 89  ? 148.102 154.824 79.053  1.00 65.14  ? 89   VAL B CG1 1 
ATOM   5386  C CG2 . VAL B 1 89  ? 148.146 157.022 80.156  1.00 65.14  ? 89   VAL B CG2 1 
ATOM   5387  N N   . TYR B 1 90  ? 150.398 154.321 83.045  1.00 66.84  ? 90   TYR B N   1 
ATOM   5388  C CA  . TYR B 1 90  ? 151.347 154.517 84.141  1.00 66.84  ? 90   TYR B CA  1 
ATOM   5389  C C   . TYR B 1 90  ? 152.771 154.409 83.601  1.00 66.84  ? 90   TYR B C   1 
ATOM   5390  O O   . TYR B 1 90  ? 153.221 153.343 83.182  1.00 66.84  ? 90   TYR B O   1 
ATOM   5391  C CB  . TYR B 1 90  ? 151.080 153.514 85.256  1.00 66.84  ? 90   TYR B CB  1 
ATOM   5392  C CG  . TYR B 1 90  ? 149.798 153.793 86.008  1.00 66.84  ? 90   TYR B CG  1 
ATOM   5393  C CD1 . TYR B 1 90  ? 149.431 155.094 86.330  1.00 66.84  ? 90   TYR B CD1 1 
ATOM   5394  C CD2 . TYR B 1 90  ? 148.948 152.760 86.381  1.00 66.84  ? 90   TYR B CD2 1 
ATOM   5395  C CE1 . TYR B 1 90  ? 148.258 155.358 87.012  1.00 66.84  ? 90   TYR B CE1 1 
ATOM   5396  C CE2 . TYR B 1 90  ? 147.770 153.016 87.065  1.00 66.84  ? 90   TYR B CE2 1 
ATOM   5397  C CZ  . TYR B 1 90  ? 147.433 154.318 87.378  1.00 66.84  ? 90   TYR B CZ  1 
ATOM   5398  O OH  . TYR B 1 90  ? 146.264 154.577 88.055  1.00 66.84  ? 90   TYR B OH  1 
ATOM   5399  N N   . GLU B 1 91  ? 153.482 155.532 83.609  1.00 77.60  ? 91   GLU B N   1 
ATOM   5400  C CA  . GLU B 1 91  ? 154.882 155.560 83.214  1.00 77.60  ? 91   GLU B CA  1 
ATOM   5401  C C   . GLU B 1 91  ? 155.758 155.045 84.360  1.00 77.60  ? 91   GLU B C   1 
ATOM   5402  O O   . GLU B 1 91  ? 155.513 155.313 85.539  1.00 77.60  ? 91   GLU B O   1 
ATOM   5403  C CB  . GLU B 1 91  ? 155.282 156.981 82.802  1.00 77.60  ? 91   GLU B CB  1 
ATOM   5404  C CG  . GLU B 1 91  ? 156.742 157.196 82.433  1.00 77.60  ? 91   GLU B CG  1 
ATOM   5405  C CD  . GLU B 1 91  ? 157.248 156.168 81.444  1.00 77.60  ? 91   GLU B CD  1 
ATOM   5406  O OE1 . GLU B 1 91  ? 156.808 156.206 80.279  1.00 77.60  ? 91   GLU B OE1 1 
ATOM   5407  O OE2 . GLU B 1 91  ? 158.081 155.322 81.830  1.00 77.60  ? 91   GLU B OE2 1 
ATOM   5408  N N   . THR B 1 92  ? 156.796 154.296 83.998  1.00 77.03  ? 92   THR B N   1 
ATOM   5409  C CA  . THR B 1 92  ? 157.653 153.594 84.942  1.00 77.03  ? 92   THR B CA  1 
ATOM   5410  C C   . THR B 1 92  ? 158.895 154.422 85.246  1.00 77.03  ? 92   THR B C   1 
ATOM   5411  O O   . THR B 1 92  ? 159.273 155.298 84.463  1.00 77.03  ? 92   THR B O   1 
ATOM   5412  C CB  . THR B 1 92  ? 158.081 152.250 84.373  1.00 77.03  ? 92   THR B CB  1 
ATOM   5413  O OG1 . THR B 1 92  ? 159.214 152.446 83.519  1.00 77.03  ? 92   THR B OG1 1 
ATOM   5414  C CG2 . THR B 1 92  ? 156.961 151.686 83.529  1.00 77.03  ? 92   THR B CG2 1 
ATOM   5415  N N   . GLU B 1 93  ? 159.529 154.141 86.383  1.00 74.99  ? 93   GLU B N   1 
ATOM   5416  C CA  . GLU B 1 93  ? 160.826 154.719 86.720  1.00 74.99  ? 93   GLU B CA  1 
ATOM   5417  C C   . GLU B 1 93  ? 161.608 153.744 87.586  1.00 74.99  ? 93   GLU B C   1 
ATOM   5418  O O   . GLU B 1 93  ? 161.091 153.248 88.593  1.00 74.99  ? 93   GLU B O   1 
ATOM   5419  C CB  . GLU B 1 93  ? 160.691 156.065 87.437  1.00 74.99  ? 93   GLU B CB  1 
ATOM   5420  C CG  . GLU B 1 93  ? 161.720 157.084 86.964  1.00 74.99  ? 93   GLU B CG  1 
ATOM   5421  C CD  . GLU B 1 93  ? 161.727 158.351 87.789  1.00 74.99  ? 93   GLU B CD  1 
ATOM   5422  O OE1 . GLU B 1 93  ? 162.373 158.353 88.860  1.00 74.99  ? 93   GLU B OE1 1 
ATOM   5423  O OE2 . GLU B 1 93  ? 161.112 159.348 87.368  1.00 74.99  ? 93   GLU B OE2 1 
ATOM   5424  N N   . LEU B 1 94  ? 162.851 153.469 87.191  1.00 74.31  ? 94   LEU B N   1 
ATOM   5425  C CA  . LEU B 1 94  ? 163.770 152.642 87.970  1.00 74.31  ? 94   LEU B CA  1 
ATOM   5426  C C   . LEU B 1 94  ? 164.741 153.575 88.689  1.00 74.31  ? 94   LEU B C   1 
ATOM   5427  O O   . LEU B 1 94  ? 165.320 154.478 88.079  1.00 74.31  ? 94   LEU B O   1 
ATOM   5428  C CB  . LEU B 1 94  ? 164.476 151.623 87.076  1.00 74.31  ? 94   LEU B CB  1 
ATOM   5429  C CG  . LEU B 1 94  ? 165.307 151.996 85.838  1.00 74.31  ? 94   LEU B CG  1 
ATOM   5430  C CD1 . LEU B 1 94  ? 166.783 152.260 86.147  1.00 74.31  ? 94   LEU B CD1 1 
ATOM   5431  C CD2 . LEU B 1 94  ? 165.171 150.900 84.792  1.00 74.31  ? 94   LEU B CD2 1 
ATOM   5432  N N   . LEU B 1 95  ? 164.878 153.390 90.000  1.00 70.59  ? 95   LEU B N   1 
ATOM   5433  C CA  . LEU B 1 95  ? 165.726 154.248 90.821  1.00 70.59  ? 95   LEU B CA  1 
ATOM   5434  C C   . LEU B 1 95  ? 166.645 153.479 91.760  1.00 70.59  ? 95   LEU B C   1 
ATOM   5435  O O   . LEU B 1 95  ? 167.748 153.946 92.050  1.00 70.59  ? 95   LEU B O   1 
ATOM   5436  C CB  . LEU B 1 95  ? 164.840 155.217 91.626  1.00 70.59  ? 95   LEU B CB  1 
ATOM   5437  C CG  . LEU B 1 95  ? 165.321 156.532 92.263  1.00 70.59  ? 95   LEU B CG  1 
ATOM   5438  C CD1 . LEU B 1 95  ? 164.110 157.420 92.490  1.00 70.59  ? 95   LEU B CD1 1 
ATOM   5439  C CD2 . LEU B 1 95  ? 166.064 156.364 93.587  1.00 70.59  ? 95   LEU B CD2 1 
ATOM   5440  N N   . GLU B 1 96  ? 166.234 152.302 92.227  1.00 71.72  ? 96   GLU B N   1 
ATOM   5441  C CA  . GLU B 1 96  ? 166.836 151.656 93.394  1.00 71.72  ? 96   GLU B CA  1 
ATOM   5442  C C   . GLU B 1 96  ? 167.879 150.602 93.039  1.00 71.72  ? 96   GLU B C   1 
ATOM   5443  O O   . GLU B 1 96  ? 168.163 149.731 93.869  1.00 71.72  ? 96   GLU B O   1 
ATOM   5444  C CB  . GLU B 1 96  ? 165.744 151.055 94.277  1.00 71.72  ? 96   GLU B CB  1 
ATOM   5445  C CG  . GLU B 1 96  ? 164.691 152.058 94.769  1.00 71.72  ? 96   GLU B CG  1 
ATOM   5446  C CD  . GLU B 1 96  ? 163.514 152.253 93.820  1.00 71.72  ? 96   GLU B CD  1 
ATOM   5447  O OE1 . GLU B 1 96  ? 162.400 152.527 94.309  1.00 71.72  ? 96   GLU B OE1 1 
ATOM   5448  O OE2 . GLU B 1 96  ? 163.699 152.150 92.591  1.00 71.72  ? 96   GLU B OE2 1 
ATOM   5449  N N   . LYS B 1 97  ? 168.457 150.676 91.832  1.00 70.09  ? 97   LYS B N   1 
ATOM   5450  C CA  . LYS B 1 97  ? 169.626 149.896 91.399  1.00 70.09  ? 97   LYS B CA  1 
ATOM   5451  C C   . LYS B 1 97  ? 169.361 148.387 91.466  1.00 70.09  ? 97   LYS B C   1 
ATOM   5452  O O   . LYS B 1 97  ? 169.929 147.658 92.282  1.00 70.09  ? 97   LYS B O   1 
ATOM   5453  C CB  . LYS B 1 97  ? 170.872 150.278 92.211  1.00 70.09  ? 97   LYS B CB  1 
ATOM   5454  C CG  . LYS B 1 97  ? 171.230 151.756 92.147  1.00 70.09  ? 97   LYS B CG  1 
ATOM   5455  C CD  . LYS B 1 97  ? 172.000 152.214 93.381  1.00 70.09  ? 97   LYS B CD  1 
ATOM   5456  C CE  . LYS B 1 97  ? 171.309 151.813 94.680  1.00 70.09  ? 97   LYS B CE  1 
ATOM   5457  N NZ  . LYS B 1 97  ? 169.940 152.386 94.804  1.00 70.09  ? 97   LYS B NZ  1 
ATOM   5458  N N   . ILE B 1 98  ? 168.452 147.947 90.591  1.00 69.33  ? 98   ILE B N   1 
ATOM   5459  C CA  . ILE B 1 98  ? 168.022 146.548 90.586  1.00 69.33  ? 98   ILE B CA  1 
ATOM   5460  C C   . ILE B 1 98  ? 169.151 145.640 90.108  1.00 69.33  ? 98   ILE B C   1 
ATOM   5461  O O   . ILE B 1 98  ? 169.605 144.750 90.835  1.00 69.33  ? 98   ILE B O   1 
ATOM   5462  C CB  . ILE B 1 98  ? 166.760 146.362 89.722  1.00 69.33  ? 98   ILE B CB  1 
ATOM   5463  C CG1 . ILE B 1 98  ? 165.574 147.172 90.263  1.00 69.33  ? 98   ILE B CG1 1 
ATOM   5464  C CG2 . ILE B 1 98  ? 166.387 144.886 89.644  1.00 69.33  ? 98   ILE B CG2 1 
ATOM   5465  C CD1 . ILE B 1 98  ? 165.347 148.520 89.578  1.00 69.33  ? 98   ILE B CD1 1 
ATOM   5466  N N   . ALA B 1 99  ? 169.624 145.852 88.880  1.00 67.64  ? 99   ALA B N   1 
ATOM   5467  C CA  . ALA B 1 99  ? 170.651 144.985 88.317  1.00 67.64  ? 99   ALA B CA  1 
ATOM   5468  C C   . ALA B 1 99  ? 171.776 145.788 87.677  1.00 67.64  ? 99   ALA B C   1 
ATOM   5469  O O   . ALA B 1 99  ? 171.751 147.024 87.690  1.00 67.64  ? 99   ALA B O   1 
ATOM   5470  C CB  . ALA B 1 99  ? 170.038 144.029 87.290  1.00 67.64  ? 99   ALA B CB  1 
ATOM   5471  N N   . ASP B 1 100 ? 172.770 145.091 87.121  1.00 72.85  ? 100  ASP B N   1 
ATOM   5472  C CA  . ASP B 1 100 ? 173.865 145.769 86.434  1.00 72.85  ? 100  ASP B CA  1 
ATOM   5473  C C   . ASP B 1 100 ? 173.392 146.380 85.120  1.00 72.85  ? 100  ASP B C   1 
ATOM   5474  O O   . ASP B 1 100 ? 173.875 147.439 84.704  1.00 72.85  ? 100  ASP B O   1 
ATOM   5475  C CB  . ASP B 1 100 ? 175.027 144.798 86.209  1.00 72.85  ? 100  ASP B CB  1 
ATOM   5476  C CG  . ASP B 1 100 ? 174.603 143.532 85.493  1.00 72.85  ? 100  ASP B CG  1 
ATOM   5477  O OD1 . ASP B 1 100 ? 173.386 143.254 85.454  1.00 72.85  ? 100  ASP B OD1 1 
ATOM   5478  O OD2 . ASP B 1 100 ? 175.482 142.816 84.969  1.00 72.85  ? 100  ASP B OD2 1 
ATOM   5479  N N   . ASP B 1 101 ? 172.451 145.724 84.452  1.00 70.06  ? 101  ASP B N   1 
ATOM   5480  C CA  . ASP B 1 101 ? 171.728 146.318 83.340  1.00 70.06  ? 101  ASP B CA  1 
ATOM   5481  C C   . ASP B 1 101 ? 170.282 145.841 83.371  1.00 70.06  ? 101  ASP B C   1 
ATOM   5482  O O   . ASP B 1 101 ? 170.001 144.645 83.268  1.00 70.06  ? 101  ASP B O   1 
ATOM   5483  C CB  . ASP B 1 101 ? 172.411 146.028 81.984  1.00 70.06  ? 101  ASP B CB  1 
ATOM   5484  C CG  . ASP B 1 101 ? 172.779 144.568 81.793  1.00 70.06  ? 101  ASP B CG  1 
ATOM   5485  O OD1 . ASP B 1 101 ? 172.625 143.764 82.733  1.00 70.06  ? 101  ASP B OD1 1 
ATOM   5486  O OD2 . ASP B 1 101 ? 173.243 144.226 80.685  1.00 70.06  ? 101  ASP B OD2 1 
ATOM   5487  N N   . THR B 1 102 ? 169.366 146.793 83.544  1.00 68.05  ? 102  THR B N   1 
ATOM   5488  C CA  . THR B 1 102 ? 167.958 146.481 83.785  1.00 68.05  ? 102  THR B CA  1 
ATOM   5489  C C   . THR B 1 102 ? 167.238 146.321 82.450  1.00 68.05  ? 102  THR B C   1 
ATOM   5490  O O   . THR B 1 102 ? 166.395 147.129 82.055  1.00 68.05  ? 102  THR B O   1 
ATOM   5491  C CB  . THR B 1 102 ? 167.317 147.564 84.641  1.00 68.05  ? 102  THR B CB  1 
ATOM   5492  O OG1 . THR B 1 102 ? 167.762 148.848 84.188  1.00 68.05  ? 102  THR B OG1 1 
ATOM   5493  C CG2 . THR B 1 102 ? 167.697 147.383 86.101  1.00 68.05  ? 102  THR B CG2 1 
ATOM   5494  N N   . ASP B 1 103 ? 167.584 145.246 81.744  1.00 68.44  ? 103  ASP B N   1 
ATOM   5495  C CA  . ASP B 1 103 ? 166.896 144.875 80.517  1.00 68.44  ? 103  ASP B CA  1 
ATOM   5496  C C   . ASP B 1 103 ? 165.634 144.066 80.775  1.00 68.44  ? 103  ASP B C   1 
ATOM   5497  O O   . ASP B 1 103 ? 164.714 144.098 79.950  1.00 68.44  ? 103  ASP B O   1 
ATOM   5498  C CB  . ASP B 1 103 ? 167.835 144.080 79.602  1.00 68.44  ? 103  ASP B CB  1 
ATOM   5499  C CG  . ASP B 1 103 ? 167.412 144.130 78.145  1.00 68.44  ? 103  ASP B CG  1 
ATOM   5500  O OD1 . ASP B 1 103 ? 166.915 143.105 77.632  1.00 68.44  ? 103  ASP B OD1 1 
ATOM   5501  O OD2 . ASP B 1 103 ? 167.574 145.195 77.512  1.00 68.44  ? 103  ASP B OD2 1 
ATOM   5502  N N   . ALA B 1 104 ? 165.567 143.350 81.895  1.00 67.66  ? 104  ALA B N   1 
ATOM   5503  C CA  . ALA B 1 104 ? 164.390 142.580 82.260  1.00 67.66  ? 104  ALA B CA  1 
ATOM   5504  C C   . ALA B 1 104 ? 163.516 143.294 83.278  1.00 67.66  ? 104  ALA B C   1 
ATOM   5505  O O   . ALA B 1 104 ? 162.385 142.857 83.518  1.00 67.66  ? 104  ALA B O   1 
ATOM   5506  C CB  . ALA B 1 104 ? 164.802 141.207 82.804  1.00 67.66  ? 104  ALA B CB  1 
ATOM   5507  N N   . ALA B 1 105 ? 164.007 144.378 83.883  1.00 63.60  ? 105  ALA B N   1 
ATOM   5508  C CA  . ALA B 1 105 ? 163.166 145.160 84.780  1.00 63.60  ? 105  ALA B CA  1 
ATOM   5509  C C   . ALA B 1 105 ? 162.098 145.923 84.012  1.00 63.60  ? 105  ALA B C   1 
ATOM   5510  O O   . ALA B 1 105 ? 161.014 146.171 84.547  1.00 63.60  ? 105  ALA B O   1 
ATOM   5511  C CB  . ALA B 1 105 ? 164.014 146.124 85.606  1.00 63.60  ? 105  ALA B CB  1 
ATOM   5512  N N   . LYS B 1 106 ? 162.379 146.303 82.766  1.00 65.24  ? 106  LYS B N   1 
ATOM   5513  C CA  . LYS B 1 106 ? 161.339 146.925 81.958  1.00 65.24  ? 106  LYS B CA  1 
ATOM   5514  C C   . LYS B 1 106 ? 160.379 145.887 81.395  1.00 65.24  ? 106  LYS B C   1 
ATOM   5515  O O   . LYS B 1 106 ? 159.241 146.226 81.055  1.00 65.24  ? 106  LYS B O   1 
ATOM   5516  C CB  . LYS B 1 106 ? 161.955 147.758 80.834  1.00 65.24  ? 106  LYS B CB  1 
ATOM   5517  C CG  . LYS B 1 106 ? 162.733 146.970 79.789  1.00 65.24  ? 106  LYS B CG  1 
ATOM   5518  C CD  . LYS B 1 106 ? 163.052 147.842 78.580  1.00 65.24  ? 106  LYS B CD  1 
ATOM   5519  C CE  . LYS B 1 106 ? 161.801 148.495 77.997  1.00 65.24  ? 106  LYS B CE  1 
ATOM   5520  N NZ  . LYS B 1 106 ? 160.709 147.510 77.734  1.00 65.24  ? 106  LYS B NZ  1 
ATOM   5521  N N   . GLU B 1 107 ? 160.813 144.624 81.293  1.00 69.65  ? 107  GLU B N   1 
ATOM   5522  C CA  . GLU B 1 107 ? 159.915 143.541 80.903  1.00 69.65  ? 107  GLU B CA  1 
ATOM   5523  C C   . GLU B 1 107 ? 158.869 143.277 81.981  1.00 69.65  ? 107  GLU B C   1 
ATOM   5524  O O   . GLU B 1 107 ? 157.753 142.847 81.660  1.00 69.65  ? 107  GLU B O   1 
ATOM   5525  C CB  . GLU B 1 107 ? 160.734 142.275 80.597  1.00 69.65  ? 107  GLU B CB  1 
ATOM   5526  C CG  . GLU B 1 107 ? 159.933 141.005 80.291  1.00 69.65  ? 107  GLU B CG  1 
ATOM   5527  C CD  . GLU B 1 107 ? 160.677 139.741 80.641  1.00 69.65  ? 107  GLU B CD  1 
ATOM   5528  O OE1 . GLU B 1 107 ? 161.472 139.254 79.811  1.00 69.65  ? 107  GLU B OE1 1 
ATOM   5529  O OE2 . GLU B 1 107 ? 160.485 139.237 81.769  1.00 69.65  ? 107  GLU B OE2 1 
ATOM   5530  N N   . PHE B 1 108 ? 159.203 143.565 83.245  1.00 70.66  ? 108  PHE B N   1 
ATOM   5531  C CA  . PHE B 1 108 ? 158.220 143.537 84.325  1.00 70.66  ? 108  PHE B CA  1 
ATOM   5532  C C   . PHE B 1 108 ? 157.093 144.530 84.053  1.00 70.66  ? 108  PHE B C   1 
ATOM   5533  O O   . PHE B 1 108 ? 155.919 144.228 84.288  1.00 70.66  ? 108  PHE B O   1 
ATOM   5534  C CB  . PHE B 1 108 ? 158.913 143.851 85.657  1.00 70.66  ? 108  PHE B CB  1 
ATOM   5535  C CG  . PHE B 1 108 ? 158.012 143.780 86.874  1.00 70.66  ? 108  PHE B CG  1 
ATOM   5536  C CD1 . PHE B 1 108 ? 156.961 142.870 86.957  1.00 70.66  ? 108  PHE B CD1 1 
ATOM   5537  C CD2 . PHE B 1 108 ? 158.217 144.648 87.936  1.00 70.66  ? 108  PHE B CD2 1 
ATOM   5538  C CE1 . PHE B 1 108 ? 156.147 142.826 88.079  1.00 70.66  ? 108  PHE B CE1 1 
ATOM   5539  C CE2 . PHE B 1 108 ? 157.402 144.610 89.056  1.00 70.66  ? 108  PHE B CE2 1 
ATOM   5540  C CZ  . PHE B 1 108 ? 156.368 143.699 89.127  1.00 70.66  ? 108  PHE B CZ  1 
ATOM   5541  N N   . PHE B 1 109 ? 157.423 145.702 83.514  1.00 71.82  ? 109  PHE B N   1 
ATOM   5542  C CA  . PHE B 1 109 ? 156.419 146.715 83.216  1.00 71.82  ? 109  PHE B CA  1 
ATOM   5543  C C   . PHE B 1 109 ? 156.115 146.851 81.730  1.00 71.82  ? 109  PHE B C   1 
ATOM   5544  O O   . PHE B 1 109 ? 155.355 147.747 81.349  1.00 71.82  ? 109  PHE B O   1 
ATOM   5545  C CB  . PHE B 1 109 ? 156.837 148.078 83.763  1.00 71.82  ? 109  PHE B CB  1 
ATOM   5546  C CG  . PHE B 1 109 ? 157.273 148.064 85.197  1.00 71.82  ? 109  PHE B CG  1 
ATOM   5547  C CD1 . PHE B 1 109 ? 156.345 148.230 86.212  1.00 71.82  ? 109  PHE B CD1 1 
ATOM   5548  C CD2 . PHE B 1 109 ? 158.614 147.981 85.528  1.00 71.82  ? 109  PHE B CD2 1 
ATOM   5549  C CE1 . PHE B 1 109 ? 156.739 148.238 87.536  1.00 71.82  ? 109  PHE B CE1 1 
ATOM   5550  C CE2 . PHE B 1 109 ? 159.020 147.997 86.849  1.00 71.82  ? 109  PHE B CE2 1 
ATOM   5551  C CZ  . PHE B 1 109 ? 158.080 148.132 87.854  1.00 71.82  ? 109  PHE B CZ  1 
ATOM   5552  N N   . ALA B 1 110 ? 156.684 145.995 80.879  1.00 68.66  ? 110  ALA B N   1 
ATOM   5553  C CA  . ALA B 1 110 ? 156.282 145.988 79.477  1.00 68.66  ? 110  ALA B CA  1 
ATOM   5554  C C   . ALA B 1 110 ? 154.903 145.382 79.285  1.00 68.66  ? 110  ALA B C   1 
ATOM   5555  O O   . ALA B 1 110 ? 154.255 145.648 78.267  1.00 68.66  ? 110  ALA B O   1 
ATOM   5556  C CB  . ALA B 1 110 ? 157.297 145.222 78.626  1.00 68.66  ? 110  ALA B CB  1 
ATOM   5557  N N   . CYS B 1 111 ? 154.442 144.585 80.244  1.00 70.19  ? 111  CYS B N   1 
ATOM   5558  C CA  . CYS B 1 111 ? 153.129 143.967 80.187  1.00 70.19  ? 111  CYS B CA  1 
ATOM   5559  C C   . CYS B 1 111 ? 152.207 144.396 81.312  1.00 70.19  ? 111  CYS B C   1 
ATOM   5560  O O   . CYS B 1 111 ? 151.010 144.537 81.074  1.00 70.19  ? 111  CYS B O   1 
ATOM   5561  C CB  . CYS B 1 111 ? 153.261 142.440 80.217  1.00 70.19  ? 111  CYS B CB  1 
ATOM   5562  S SG  . CYS B 1 111 ? 154.404 141.829 81.476  1.00 70.19  ? 111  CYS B SG  1 
ATOM   5563  N N   . LEU B 1 112 ? 152.741 144.641 82.515  1.00 66.74  ? 112  LEU B N   1 
ATOM   5564  C CA  . LEU B 1 112 ? 151.917 144.860 83.702  1.00 66.74  ? 112  LEU B CA  1 
ATOM   5565  C C   . LEU B 1 112 ? 151.113 146.150 83.640  1.00 66.74  ? 112  LEU B C   1 
ATOM   5566  O O   . LEU B 1 112 ? 149.956 146.168 84.069  1.00 66.74  ? 112  LEU B O   1 
ATOM   5567  C CB  . LEU B 1 112 ? 152.799 144.844 84.956  1.00 66.74  ? 112  LEU B CB  1 
ATOM   5568  C CG  . LEU B 1 112 ? 152.222 145.106 86.351  1.00 66.74  ? 112  LEU B CG  1 
ATOM   5569  C CD1 . LEU B 1 112 ? 152.835 144.175 87.375  1.00 66.74  ? 112  LEU B CD1 1 
ATOM   5570  C CD2 . LEU B 1 112 ? 152.530 146.538 86.764  1.00 66.74  ? 112  LEU B CD2 1 
ATOM   5571  N N   . ASP B 1 113 ? 151.695 147.227 83.116  1.00 70.23  ? 113  ASP B N   1 
ATOM   5572  C CA  . ASP B 1 113 ? 150.941 148.468 82.992  1.00 70.23  ? 113  ASP B CA  1 
ATOM   5573  C C   . ASP B 1 113 ? 149.905 148.381 81.881  1.00 70.23  ? 113  ASP B C   1 
ATOM   5574  O O   . ASP B 1 113 ? 148.938 149.149 81.877  1.00 70.23  ? 113  ASP B O   1 
ATOM   5575  C CB  . ASP B 1 113 ? 151.900 149.632 82.776  1.00 70.23  ? 113  ASP B CB  1 
ATOM   5576  C CG  . ASP B 1 113 ? 152.899 149.760 83.904  1.00 70.23  ? 113  ASP B CG  1 
ATOM   5577  O OD1 . ASP B 1 113 ? 152.886 150.787 84.615  1.00 70.23  ? 113  ASP B OD1 1 
ATOM   5578  O OD2 . ASP B 1 113 ? 153.673 148.805 84.104  1.00 70.23  ? 113  ASP B OD2 1 
ATOM   5579  N N   . MET B 1 114 ? 150.088 147.460 80.935  1.00 73.48  ? 114  MET B N   1 
ATOM   5580  C CA  . MET B 1 114 ? 149.015 147.146 80.006  1.00 73.48  ? 114  MET B CA  1 
ATOM   5581  C C   . MET B 1 114 ? 147.886 146.378 80.679  1.00 73.48  ? 114  MET B C   1 
ATOM   5582  O O   . MET B 1 114 ? 146.729 146.530 80.274  1.00 73.48  ? 114  MET B O   1 
ATOM   5583  C CB  . MET B 1 114 ? 149.549 146.351 78.811  1.00 73.48  ? 114  MET B CB  1 
ATOM   5584  C CG  . MET B 1 114 ? 150.881 146.831 78.222  1.00 73.48  ? 114  MET B CG  1 
ATOM   5585  S SD  . MET B 1 114 ? 150.880 148.520 77.570  1.00 73.48  ? 114  MET B SD  1 
ATOM   5586  C CE  . MET B 1 114 ? 151.779 149.433 78.826  1.00 73.48  ? 114  MET B CE  1 
ATOM   5587  N N   . GLN B 1 115 ? 148.189 145.568 81.702  1.00 66.78  ? 115  GLN B N   1 
ATOM   5588  C CA  . GLN B 1 115 ? 147.130 144.918 82.468  1.00 66.78  ? 115  GLN B CA  1 
ATOM   5589  C C   . GLN B 1 115 ? 146.326 145.909 83.291  1.00 66.78  ? 115  GLN B C   1 
ATOM   5590  O O   . GLN B 1 115 ? 145.177 145.616 83.637  1.00 66.78  ? 115  GLN B O   1 
ATOM   5591  C CB  . GLN B 1 115 ? 147.690 143.843 83.401  1.00 66.78  ? 115  GLN B CB  1 
ATOM   5592  C CG  . GLN B 1 115 ? 148.812 143.024 82.828  1.00 66.78  ? 115  GLN B CG  1 
ATOM   5593  C CD  . GLN B 1 115 ? 148.320 141.894 81.959  1.00 66.78  ? 115  GLN B CD  1 
ATOM   5594  O OE1 . GLN B 1 115 ? 147.735 140.936 82.451  1.00 66.78  ? 115  GLN B OE1 1 
ATOM   5595  N NE2 . GLN B 1 115 ? 148.557 141.998 80.657  1.00 66.78  ? 115  GLN B NE2 1 
ATOM   5596  N N   . LEU B 1 116 ? 146.913 147.055 83.640  1.00 62.38  ? 116  LEU B N   1 
ATOM   5597  C CA  . LEU B 1 116 ? 146.132 148.136 84.223  1.00 62.38  ? 116  LEU B CA  1 
ATOM   5598  C C   . LEU B 1 116 ? 145.107 148.648 83.223  1.00 62.38  ? 116  LEU B C   1 
ATOM   5599  O O   . LEU B 1 116 ? 143.931 148.824 83.555  1.00 62.38  ? 116  LEU B O   1 
ATOM   5600  C CB  . LEU B 1 116 ? 147.045 149.275 84.686  1.00 62.38  ? 116  LEU B CB  1 
ATOM   5601  C CG  . LEU B 1 116 ? 147.658 149.276 86.095  1.00 62.38  ? 116  LEU B CG  1 
ATOM   5602  C CD1 . LEU B 1 116 ? 146.561 149.315 87.151  1.00 62.38  ? 116  LEU B CD1 1 
ATOM   5603  C CD2 . LEU B 1 116 ? 148.612 148.123 86.345  1.00 62.38  ? 116  LEU B CD2 1 
ATOM   5604  N N   . ASN B 1 117 ? 145.538 148.863 81.977  1.00 62.38  ? 117  ASN B N   1 
ATOM   5605  C CA  . ASN B 1 117 ? 144.635 149.374 80.952  1.00 62.38  ? 117  ASN B CA  1 
ATOM   5606  C C   . ASN B 1 117 ? 143.614 148.327 80.543  1.00 62.38  ? 117  ASN B C   1 
ATOM   5607  O O   . ASN B 1 117 ? 142.457 148.661 80.265  1.00 62.38  ? 117  ASN B O   1 
ATOM   5608  C CB  . ASN B 1 117 ? 145.430 149.821 79.730  1.00 62.38  ? 117  ASN B CB  1 
ATOM   5609  C CG  . ASN B 1 117 ? 146.371 150.951 80.035  1.00 62.38  ? 117  ASN B CG  1 
ATOM   5610  O OD1 . ASN B 1 117 ? 146.835 151.095 81.164  1.00 62.38  ? 117  ASN B OD1 1 
ATOM   5611  N ND2 . ASN B 1 117 ? 146.663 151.764 79.029  1.00 62.38  ? 117  ASN B ND2 1 
ATOM   5612  N N   . LYS B 1 118 ? 144.028 147.053 80.519  1.00 59.65  ? 118  LYS B N   1 
ATOM   5613  C CA  . LYS B 1 118 ? 143.184 145.955 80.052  1.00 59.65  ? 118  LYS B CA  1 
ATOM   5614  C C   . LYS B 1 118 ? 141.936 145.797 80.905  1.00 59.65  ? 118  LYS B C   1 
ATOM   5615  O O   . LYS B 1 118 ? 140.856 145.501 80.382  1.00 59.65  ? 118  LYS B O   1 
ATOM   5616  C CB  . LYS B 1 118 ? 143.991 144.656 80.049  1.00 59.65  ? 118  LYS B CB  1 
ATOM   5617  C CG  . LYS B 1 118 ? 143.305 143.468 79.402  1.00 59.65  ? 118  LYS B CG  1 
ATOM   5618  C CD  . LYS B 1 118 ? 143.969 142.167 79.823  1.00 59.65  ? 118  LYS B CD  1 
ATOM   5619  C CE  . LYS B 1 118 ? 143.709 141.864 81.289  1.00 59.65  ? 118  LYS B CE  1 
ATOM   5620  N NZ  . LYS B 1 118 ? 144.035 140.456 81.646  1.00 59.65  ? 118  LYS B NZ  1 
ATOM   5621  N N   . VAL B 1 119 ? 142.061 146.009 82.209  1.00 55.28  ? 119  VAL B N   1 
ATOM   5622  C CA  . VAL B 1 119 ? 140.883 146.105 83.050  1.00 55.28  ? 119  VAL B CA  1 
ATOM   5623  C C   . VAL B 1 119 ? 140.212 147.466 82.898  1.00 55.28  ? 119  VAL B C   1 
ATOM   5624  O O   . VAL B 1 119 ? 138.983 147.553 82.924  1.00 55.28  ? 119  VAL B O   1 
ATOM   5625  C CB  . VAL B 1 119 ? 141.265 145.826 84.511  1.00 55.28  ? 119  VAL B CB  1 
ATOM   5626  C CG1 . VAL B 1 119 ? 140.034 145.608 85.358  1.00 55.28  ? 119  VAL B CG1 1 
ATOM   5627  C CG2 . VAL B 1 119 ? 142.170 144.613 84.591  1.00 55.28  ? 119  VAL B CG2 1 
ATOM   5628  N N   . ASN B 1 120 ? 140.989 148.528 82.673  1.00 59.36  ? 120  ASN B N   1 
ATOM   5629  C CA  . ASN B 1 120 ? 140.416 149.871 82.707  1.00 59.36  ? 120  ASN B CA  1 
ATOM   5630  C C   . ASN B 1 120 ? 139.738 150.223 81.394  1.00 59.36  ? 120  ASN B C   1 
ATOM   5631  O O   . ASN B 1 120 ? 138.766 150.985 81.378  1.00 59.36  ? 120  ASN B O   1 
ATOM   5632  C CB  . ASN B 1 120 ? 141.490 150.899 83.042  1.00 59.36  ? 120  ASN B CB  1 
ATOM   5633  C CG  . ASN B 1 120 ? 141.817 150.932 84.516  1.00 59.36  ? 120  ASN B CG  1 
ATOM   5634  O OD1 . ASN B 1 120 ? 142.603 151.759 84.967  1.00 59.36  ? 120  ASN B OD1 1 
ATOM   5635  N ND2 . ASN B 1 120 ? 141.204 150.039 85.281  1.00 59.36  ? 120  ASN B ND2 1 
ATOM   5636  N N   . GLN B 1 121 ? 140.244 149.696 80.276  1.00 57.85  ? 121  GLN B N   1 
ATOM   5637  C CA  . GLN B 1 121 ? 139.523 149.872 79.020  1.00 57.85  ? 121  GLN B CA  1 
ATOM   5638  C C   . GLN B 1 121 ? 138.221 149.082 79.016  1.00 57.85  ? 121  GLN B C   1 
ATOM   5639  O O   . GLN B 1 121 ? 137.242 149.511 78.397  1.00 57.85  ? 121  GLN B O   1 
ATOM   5640  C CB  . GLN B 1 121 ? 140.392 149.469 77.825  1.00 57.85  ? 121  GLN B CB  1 
ATOM   5641  C CG  . GLN B 1 121 ? 141.626 150.340 77.606  1.00 57.85  ? 121  GLN B CG  1 
ATOM   5642  C CD  . GLN B 1 121 ? 142.811 149.558 77.056  1.00 57.85  ? 121  GLN B CD  1 
ATOM   5643  O OE1 . GLN B 1 121 ? 143.044 148.411 77.434  1.00 57.85  ? 121  GLN B OE1 1 
ATOM   5644  N NE2 . GLN B 1 121 ? 143.570 150.186 76.165  1.00 57.85  ? 121  GLN B NE2 1 
ATOM   5645  N N   . PHE B 1 122 ? 138.181 147.946 79.715  1.00 55.70  ? 122  PHE B N   1 
ATOM   5646  C CA  . PHE B 1 122 ? 136.986 147.112 79.679  1.00 55.70  ? 122  PHE B CA  1 
ATOM   5647  C C   . PHE B 1 122 ? 135.954 147.571 80.702  1.00 55.70  ? 122  PHE B C   1 
ATOM   5648  O O   . PHE B 1 122 ? 134.776 147.722 80.364  1.00 55.70  ? 122  PHE B O   1 
ATOM   5649  C CB  . PHE B 1 122 ? 137.350 145.643 79.900  1.00 55.70  ? 122  PHE B CB  1 
ATOM   5650  C CG  . PHE B 1 122 ? 136.159 144.723 79.937  1.00 55.70  ? 122  PHE B CG  1 
ATOM   5651  C CD1 . PHE B 1 122 ? 135.998 143.820 80.970  1.00 55.70  ? 122  PHE B CD1 1 
ATOM   5652  C CD2 . PHE B 1 122 ? 135.196 144.771 78.940  1.00 55.70  ? 122  PHE B CD2 1 
ATOM   5653  C CE1 . PHE B 1 122 ? 134.905 142.977 81.009  1.00 55.70  ? 122  PHE B CE1 1 
ATOM   5654  C CE2 . PHE B 1 122 ? 134.098 143.935 78.975  1.00 55.70  ? 122  PHE B CE2 1 
ATOM   5655  C CZ  . PHE B 1 122 ? 133.954 143.036 80.011  1.00 55.70  ? 122  PHE B CZ  1 
ATOM   5656  N N   . TYR B 1 123 ? 136.380 147.785 81.958  1.00 55.72  ? 123  TYR B N   1 
ATOM   5657  C CA  . TYR B 1 123 ? 135.452 148.135 83.036  1.00 55.72  ? 123  TYR B CA  1 
ATOM   5658  C C   . TYR B 1 123 ? 134.767 149.465 82.767  1.00 55.72  ? 123  TYR B C   1 
ATOM   5659  O O   . TYR B 1 123 ? 133.591 149.635 83.097  1.00 55.72  ? 123  TYR B O   1 
ATOM   5660  C CB  . TYR B 1 123 ? 136.186 148.178 84.384  1.00 55.72  ? 123  TYR B CB  1 
ATOM   5661  C CG  . TYR B 1 123 ? 135.328 148.350 85.642  1.00 55.72  ? 123  TYR B CG  1 
ATOM   5662  C CD1 . TYR B 1 123 ? 134.889 149.610 86.060  1.00 55.72  ? 123  TYR B CD1 1 
ATOM   5663  C CD2 . TYR B 1 123 ? 135.010 147.259 86.445  1.00 55.72  ? 123  TYR B CD2 1 
ATOM   5664  C CE1 . TYR B 1 123 ? 134.120 149.768 87.201  1.00 55.72  ? 123  TYR B CE1 1 
ATOM   5665  C CE2 . TYR B 1 123 ? 134.254 147.417 87.602  1.00 55.72  ? 123  TYR B CE2 1 
ATOM   5666  C CZ  . TYR B 1 123 ? 133.818 148.676 87.970  1.00 55.72  ? 123  TYR B CZ  1 
ATOM   5667  O OH  . TYR B 1 123 ? 133.064 148.852 89.105  1.00 55.72  ? 123  TYR B OH  1 
ATOM   5668  N N   . LYS B 1 124 ? 135.493 150.422 82.185  1.00 55.56  ? 124  LYS B N   1 
ATOM   5669  C CA  . LYS B 1 124 ? 134.864 151.672 81.777  1.00 55.56  ? 124  LYS B CA  1 
ATOM   5670  C C   . LYS B 1 124 ? 133.860 151.434 80.661  1.00 55.56  ? 124  LYS B C   1 
ATOM   5671  O O   . LYS B 1 124 ? 132.776 152.025 80.660  1.00 55.56  ? 124  LYS B O   1 
ATOM   5672  C CB  . LYS B 1 124 ? 135.923 152.680 81.335  1.00 55.56  ? 124  LYS B CB  1 
ATOM   5673  C CG  . LYS B 1 124 ? 135.371 154.059 81.051  1.00 55.56  ? 124  LYS B CG  1 
ATOM   5674  C CD  . LYS B 1 124 ? 134.757 154.643 82.303  1.00 55.56  ? 124  LYS B CD  1 
ATOM   5675  C CE  . LYS B 1 124 ? 134.015 155.935 82.036  1.00 55.56  ? 124  LYS B CE  1 
ATOM   5676  N NZ  . LYS B 1 124 ? 132.807 155.715 81.202  1.00 55.56  ? 124  LYS B NZ  1 
ATOM   5677  N N   . THR B 1 125 ? 134.188 150.544 79.724  1.00 55.41  ? 125  THR B N   1 
ATOM   5678  C CA  . THR B 1 125 ? 133.269 150.249 78.633  1.00 55.41  ? 125  THR B CA  1 
ATOM   5679  C C   . THR B 1 125 ? 132.158 149.312 79.088  1.00 55.41  ? 125  THR B C   1 
ATOM   5680  O O   . THR B 1 125 ? 131.010 149.456 78.650  1.00 55.41  ? 125  THR B O   1 
ATOM   5681  C CB  . THR B 1 125 ? 134.046 149.655 77.459  1.00 55.41  ? 125  THR B CB  1 
ATOM   5682  O OG1 . THR B 1 125 ? 135.127 150.534 77.124  1.00 55.41  ? 125  THR B OG1 1 
ATOM   5683  C CG2 . THR B 1 125 ? 133.158 149.498 76.229  1.00 55.41  ? 125  THR B CG2 1 
ATOM   5684  N N   . LYS B 1 126 ? 132.467 148.370 79.985  1.00 56.47  ? 126  LYS B N   1 
ATOM   5685  C CA  . LYS B 1 126 ? 131.420 147.517 80.538  1.00 56.47  ? 126  LYS B CA  1 
ATOM   5686  C C   . LYS B 1 126 ? 130.487 148.303 81.444  1.00 56.47  ? 126  LYS B C   1 
ATOM   5687  O O   . LYS B 1 126 ? 129.294 147.993 81.513  1.00 56.47  ? 126  LYS B O   1 
ATOM   5688  C CB  . LYS B 1 126 ? 132.020 146.336 81.303  1.00 56.47  ? 126  LYS B CB  1 
ATOM   5689  C CG  . LYS B 1 126 ? 131.069 145.159 81.484  1.00 56.47  ? 126  LYS B CG  1 
ATOM   5690  C CD  . LYS B 1 126 ? 130.375 144.789 80.182  1.00 56.47  ? 126  LYS B CD  1 
ATOM   5691  C CE  . LYS B 1 126 ? 129.099 144.008 80.436  1.00 56.47  ? 126  LYS B CE  1 
ATOM   5692  N NZ  . LYS B 1 126 ? 128.524 143.467 79.175  1.00 56.47  ? 126  LYS B NZ  1 
ATOM   5693  N N   . GLU B 1 127 ? 131.004 149.313 82.146  1.00 56.22  ? 127  GLU B N   1 
ATOM   5694  C CA  . GLU B 1 127 ? 130.106 150.263 82.786  1.00 56.22  ? 127  GLU B CA  1 
ATOM   5695  C C   . GLU B 1 127 ? 129.378 151.106 81.753  1.00 56.22  ? 127  GLU B C   1 
ATOM   5696  O O   . GLU B 1 127 ? 128.198 151.406 81.933  1.00 56.22  ? 127  GLU B O   1 
ATOM   5697  C CB  . GLU B 1 127 ? 130.854 151.159 83.769  1.00 56.22  ? 127  GLU B CB  1 
ATOM   5698  C CG  . GLU B 1 127 ? 129.966 151.758 84.853  1.00 56.22  ? 127  GLU B CG  1 
ATOM   5699  C CD  . GLU B 1 127 ? 130.708 152.742 85.740  1.00 56.22  ? 127  GLU B CD  1 
ATOM   5700  O OE1 . GLU B 1 127 ? 130.287 153.912 85.802  1.00 56.22  ? 127  GLU B OE1 1 
ATOM   5701  O OE2 . GLU B 1 127 ? 131.692 152.343 86.394  1.00 56.22  ? 127  GLU B OE2 1 
ATOM   5702  N N   . LYS B 1 128 ? 130.060 151.498 80.668  1.00 58.40  ? 128  LYS B N   1 
ATOM   5703  C CA  . LYS B 1 128 ? 129.401 152.265 79.609  1.00 58.40  ? 128  LYS B CA  1 
ATOM   5704  C C   . LYS B 1 128 ? 128.329 151.448 78.907  1.00 58.40  ? 128  LYS B C   1 
ATOM   5705  O O   . LYS B 1 128 ? 127.288 151.995 78.525  1.00 58.40  ? 128  LYS B O   1 
ATOM   5706  C CB  . LYS B 1 128 ? 130.418 152.757 78.578  1.00 58.40  ? 128  LYS B CB  1 
ATOM   5707  C CG  . LYS B 1 128 ? 130.966 154.149 78.835  1.00 58.40  ? 128  LYS B CG  1 
ATOM   5708  C CD  . LYS B 1 128 ? 132.308 154.337 78.142  1.00 58.40  ? 128  LYS B CD  1 
ATOM   5709  C CE  . LYS B 1 128 ? 132.154 154.462 76.638  1.00 58.40  ? 128  LYS B CE  1 
ATOM   5710  N NZ  . LYS B 1 128 ? 131.410 155.694 76.259  1.00 58.40  ? 128  LYS B NZ  1 
ATOM   5711  N N   . GLU B 1 129 ? 128.569 150.148 78.717  1.00 55.59  ? 129  GLU B N   1 
ATOM   5712  C CA  . GLU B 1 129 ? 127.508 149.269 78.245  1.00 55.59  ? 129  GLU B CA  1 
ATOM   5713  C C   . GLU B 1 129 ? 126.409 149.153 79.289  1.00 55.59  ? 129  GLU B C   1 
ATOM   5714  O O   . GLU B 1 129 ? 125.225 149.155 78.940  1.00 55.59  ? 129  GLU B O   1 
ATOM   5715  C CB  . GLU B 1 129 ? 128.079 147.890 77.895  1.00 55.59  ? 129  GLU B CB  1 
ATOM   5716  C CG  . GLU B 1 129 ? 127.310 147.103 76.820  1.00 55.59  ? 129  GLU B CG  1 
ATOM   5717  C CD  . GLU B 1 129 ? 125.963 146.576 77.282  1.00 55.59  ? 129  GLU B CD  1 
ATOM   5718  O OE1 . GLU B 1 129 ? 125.034 146.500 76.451  1.00 55.59  ? 129  GLU B OE1 1 
ATOM   5719  O OE2 . GLU B 1 129 ? 125.835 146.218 78.470  1.00 55.59  ? 129  GLU B OE2 1 
ATOM   5720  N N   . PHE B 1 130 ? 126.777 149.068 80.564  1.00 55.97  ? 130  PHE B N   1 
ATOM   5721  C CA  . PHE B 1 130 ? 125.794 149.060 81.637  1.00 55.97  ? 130  PHE B CA  1 
ATOM   5722  C C   . PHE B 1 130 ? 125.305 150.452 82.005  1.00 55.97  ? 130  PHE B C   1 
ATOM   5723  O O   . PHE B 1 130 ? 124.442 150.566 82.875  1.00 55.97  ? 130  PHE B O   1 
ATOM   5724  C CB  . PHE B 1 130 ? 126.366 148.367 82.871  1.00 55.97  ? 130  PHE B CB  1 
ATOM   5725  C CG  . PHE B 1 130 ? 126.211 146.877 82.851  1.00 55.97  ? 130  PHE B CG  1 
ATOM   5726  C CD1 . PHE B 1 130 ? 125.081 146.295 82.302  1.00 55.97  ? 130  PHE B CD1 1 
ATOM   5727  C CD2 . PHE B 1 130 ? 127.203 146.057 83.361  1.00 55.97  ? 130  PHE B CD2 1 
ATOM   5728  C CE1 . PHE B 1 130 ? 124.936 144.926 82.280  1.00 55.97  ? 130  PHE B CE1 1 
ATOM   5729  C CE2 . PHE B 1 130 ? 127.063 144.688 83.344  1.00 55.97  ? 130  PHE B CE2 1 
ATOM   5730  C CZ  . PHE B 1 130 ? 125.928 144.122 82.800  1.00 55.97  ? 130  PHE B CZ  1 
ATOM   5731  N N   . LEU B 1 131 ? 125.876 151.512 81.423  1.00 57.66  ? 131  LEU B N   1 
ATOM   5732  C CA  . LEU B 1 131 ? 125.145 152.771 81.361  1.00 57.66  ? 131  LEU B CA  1 
ATOM   5733  C C   . LEU B 1 131 ? 124.145 152.749 80.221  1.00 57.66  ? 131  LEU B C   1 
ATOM   5734  O O   . LEU B 1 131 ? 123.016 153.213 80.392  1.00 57.66  ? 131  LEU B O   1 
ATOM   5735  C CB  . LEU B 1 131 ? 126.077 153.980 81.202  1.00 57.66  ? 131  LEU B CB  1 
ATOM   5736  C CG  . LEU B 1 131 ? 127.105 154.406 82.259  1.00 57.66  ? 131  LEU B CG  1 
ATOM   5737  C CD1 . LEU B 1 131 ? 127.512 155.866 82.076  1.00 57.66  ? 131  LEU B CD1 1 
ATOM   5738  C CD2 . LEU B 1 131 ? 126.606 154.139 83.676  1.00 57.66  ? 131  LEU B CD2 1 
ATOM   5739  N N   . GLU B 1 132 ? 124.535 152.202 79.067  1.00 58.50  ? 132  GLU B N   1 
ATOM   5740  C CA  . GLU B 1 132 ? 123.585 151.976 77.984  1.00 58.50  ? 132  GLU B CA  1 
ATOM   5741  C C   . GLU B 1 132 ? 122.545 150.945 78.397  1.00 58.50  ? 132  GLU B C   1 
ATOM   5742  O O   . GLU B 1 132 ? 121.375 151.033 78.011  1.00 58.50  ? 132  GLU B O   1 
ATOM   5743  C CB  . GLU B 1 132 ? 124.324 151.522 76.726  1.00 58.50  ? 132  GLU B CB  1 
ATOM   5744  C CG  . GLU B 1 132 ? 123.499 151.591 75.453  1.00 58.50  ? 132  GLU B CG  1 
ATOM   5745  C CD  . GLU B 1 132 ? 123.226 153.014 75.010  1.00 58.50  ? 132  GLU B CD  1 
ATOM   5746  O OE1 . GLU B 1 132 ? 124.124 153.630 74.399  1.00 58.50  ? 132  GLU B OE1 1 
ATOM   5747  O OE2 . GLU B 1 132 ? 122.116 153.523 75.271  1.00 58.50  ? 132  GLU B OE2 1 
ATOM   5748  N N   . ARG B 1 133 ? 122.957 149.964 79.194  1.00 55.10  ? 133  ARG B N   1 
ATOM   5749  C CA  . ARG B 1 133 ? 122.038 149.136 79.954  1.00 55.10  ? 133  ARG B CA  1 
ATOM   5750  C C   . ARG B 1 133 ? 121.834 149.665 81.362  1.00 55.10  ? 133  ARG B C   1 
ATOM   5751  O O   . ARG B 1 133 ? 121.819 148.876 82.311  1.00 55.10  ? 133  ARG B O   1 
ATOM   5752  C CB  . ARG B 1 133 ? 122.514 147.682 80.001  1.00 55.10  ? 133  ARG B CB  1 
ATOM   5753  C CG  . ARG B 1 133 ? 122.246 146.909 78.722  1.00 55.10  ? 133  ARG B CG  1 
ATOM   5754  C CD  . ARG B 1 133 ? 121.742 145.501 79.026  1.00 55.10  ? 133  ARG B CD  1 
ATOM   5755  N NE  . ARG B 1 133 ? 122.787 144.630 79.547  1.00 55.10  ? 133  ARG B NE  1 
ATOM   5756  C CZ  . ARG B 1 133 ? 123.628 143.940 78.787  1.00 55.10  ? 133  ARG B CZ  1 
ATOM   5757  N NH1 . ARG B 1 133 ? 123.546 144.013 77.466  1.00 55.10  ? 133  ARG B NH1 1 
ATOM   5758  N NH2 . ARG B 1 133 ? 124.552 143.174 79.346  1.00 55.10  ? 133  ARG B NH2 1 
ATOM   5759  N N   . GLY B 1 134 ? 121.808 150.986 81.528  1.00 56.06  ? 134  GLY B N   1 
ATOM   5760  C CA  . GLY B 1 134 ? 121.421 151.600 82.780  1.00 56.06  ? 134  GLY B CA  1 
ATOM   5761  C C   . GLY B 1 134 ? 120.526 152.806 82.610  1.00 56.06  ? 134  GLY B C   1 
ATOM   5762  O O   . GLY B 1 134 ? 120.020 153.338 83.600  1.00 56.06  ? 134  GLY B O   1 
ATOM   5763  N N   . GLU B 1 135 ? 120.325 153.257 81.369  1.00 60.81  ? 135  GLU B N   1 
ATOM   5764  C CA  . GLU B 1 135 ? 119.397 154.358 81.118  1.00 60.81  ? 135  GLU B CA  1 
ATOM   5765  C C   . GLU B 1 135 ? 118.282 154.025 80.140  1.00 60.81  ? 135  GLU B C   1 
ATOM   5766  O O   . GLU B 1 135 ? 117.226 154.662 80.219  1.00 60.81  ? 135  GLU B O   1 
ATOM   5767  C CB  . GLU B 1 135 ? 120.138 155.611 80.623  1.00 60.81  ? 135  GLU B CB  1 
ATOM   5768  C CG  . GLU B 1 135 ? 120.978 155.447 79.367  1.00 60.81  ? 135  GLU B CG  1 
ATOM   5769  C CD  . GLU B 1 135 ? 120.258 155.851 78.101  1.00 60.81  ? 135  GLU B CD  1 
ATOM   5770  O OE1 . GLU B 1 135 ? 119.339 156.692 78.178  1.00 60.81  ? 135  GLU B OE1 1 
ATOM   5771  O OE2 . GLU B 1 135 ? 120.629 155.341 77.025  1.00 60.81  ? 135  GLU B OE2 1 
ATOM   5772  N N   . CYS B 1 136 ? 118.454 153.062 79.229  1.00 61.99  ? 136  CYS B N   1 
ATOM   5773  C CA  . CYS B 1 136 ? 117.318 152.614 78.428  1.00 61.99  ? 136  CYS B CA  1 
ATOM   5774  C C   . CYS B 1 136 ? 116.329 151.818 79.265  1.00 61.99  ? 136  CYS B C   1 
ATOM   5775  O O   . CYS B 1 136 ? 115.145 151.747 78.922  1.00 61.99  ? 136  CYS B O   1 
ATOM   5776  C CB  . CYS B 1 136 ? 117.785 151.787 77.230  1.00 61.99  ? 136  CYS B CB  1 
ATOM   5777  S SG  . CYS B 1 136 ? 119.121 152.526 76.268  1.00 61.99  ? 136  CYS B SG  1 
ATOM   5778  N N   . LEU B 1 137 ? 116.789 151.218 80.365  1.00 61.13  ? 137  LEU B N   1 
ATOM   5779  C CA  . LEU B 1 137 ? 115.866 150.574 81.286  1.00 61.13  ? 137  LEU B CA  1 
ATOM   5780  C C   . LEU B 1 137 ? 115.096 151.586 82.116  1.00 61.13  ? 137  LEU B C   1 
ATOM   5781  O O   . LEU B 1 137 ? 113.986 151.280 82.552  1.00 61.13  ? 137  LEU B O   1 
ATOM   5782  C CB  . LEU B 1 137 ? 116.620 149.599 82.190  1.00 61.13  ? 137  LEU B CB  1 
ATOM   5783  C CG  . LEU B 1 137 ? 117.683 150.080 83.182  1.00 61.13  ? 137  LEU B CG  1 
ATOM   5784  C CD1 . LEU B 1 137 ? 117.144 150.313 84.577  1.00 61.13  ? 137  LEU B CD1 1 
ATOM   5785  C CD2 . LEU B 1 137 ? 118.748 149.055 83.257  1.00 61.13  ? 137  LEU B CD2 1 
ATOM   5786  N N   . LYS B 1 138 ? 115.663 152.773 82.355  1.00 61.13  ? 138  LYS B N   1 
ATOM   5787  C CA  . LYS B 1 138 ? 114.913 153.829 83.032  1.00 61.13  ? 138  LYS B CA  1 
ATOM   5788  C C   . LYS B 1 138 ? 113.724 154.271 82.196  1.00 61.13  ? 138  LYS B C   1 
ATOM   5789  O O   . LYS B 1 138 ? 112.665 154.599 82.740  1.00 61.13  ? 138  LYS B O   1 
ATOM   5790  C CB  . LYS B 1 138 ? 115.808 155.034 83.333  1.00 61.13  ? 138  LYS B CB  1 
ATOM   5791  C CG  . LYS B 1 138 ? 117.114 154.735 84.040  1.00 61.13  ? 138  LYS B CG  1 
ATOM   5792  C CD  . LYS B 1 138 ? 116.933 153.901 85.296  1.00 61.13  ? 138  LYS B CD  1 
ATOM   5793  C CE  . LYS B 1 138 ? 116.484 154.736 86.478  1.00 61.13  ? 138  LYS B CE  1 
ATOM   5794  N NZ  . LYS B 1 138 ? 115.750 153.903 87.468  1.00 61.13  ? 138  LYS B NZ  1 
ATOM   5795  N N   . LYS B 1 139 ? 113.879 154.276 80.874  1.00 64.05  ? 139  LYS B N   1 
ATOM   5796  C CA  . LYS B 1 139 ? 112.761 154.585 79.996  1.00 64.05  ? 139  LYS B CA  1 
ATOM   5797  C C   . LYS B 1 139 ? 111.856 153.375 79.808  1.00 64.05  ? 139  LYS B C   1 
ATOM   5798  O O   . LYS B 1 139 ? 110.645 153.530 79.615  1.00 64.05  ? 139  LYS B O   1 
ATOM   5799  C CB  . LYS B 1 139 ? 113.280 155.086 78.649  1.00 64.05  ? 139  LYS B CB  1 
ATOM   5800  C CG  . LYS B 1 139 ? 112.439 156.187 78.023  1.00 64.05  ? 139  LYS B CG  1 
ATOM   5801  C CD  . LYS B 1 139 ? 112.627 156.231 76.516  1.00 64.05  ? 139  LYS B CD  1 
ATOM   5802  C CE  . LYS B 1 139 ? 112.069 157.516 75.926  1.00 64.05  ? 139  LYS B CE  1 
ATOM   5803  N NZ  . LYS B 1 139 ? 112.531 157.737 74.527  1.00 64.05  ? 139  LYS B NZ  1 
ATOM   5804  N N   . GLN B 1 140 ? 112.423 152.164 79.854  1.00 62.14  ? 140  GLN B N   1 
ATOM   5805  C CA  . GLN B 1 140 ? 111.615 150.963 79.659  1.00 62.14  ? 140  GLN B CA  1 
ATOM   5806  C C   . GLN B 1 140 ? 110.734 150.674 80.872  1.00 62.14  ? 140  GLN B C   1 
ATOM   5807  O O   . GLN B 1 140 ? 109.584 150.251 80.710  1.00 62.14  ? 140  GLN B O   1 
ATOM   5808  C CB  . GLN B 1 140 ? 112.514 149.768 79.325  1.00 62.14  ? 140  GLN B CB  1 
ATOM   5809  C CG  . GLN B 1 140 ? 111.779 148.437 79.159  1.00 62.14  ? 140  GLN B CG  1 
ATOM   5810  C CD  . GLN B 1 140 ? 111.322 148.188 77.729  1.00 62.14  ? 140  GLN B CD  1 
ATOM   5811  O OE1 . GLN B 1 140 ? 111.459 149.051 76.861  1.00 62.14  ? 140  GLN B OE1 1 
ATOM   5812  N NE2 . GLN B 1 140 ? 110.768 147.006 77.481  1.00 62.14  ? 140  GLN B NE2 1 
ATOM   5813  N N   . MET B 1 141 ? 111.232 150.911 82.089  1.00 70.61  ? 141  MET B N   1 
ATOM   5814  C CA  . MET B 1 141 ? 110.346 150.828 83.243  1.00 70.61  ? 141  MET B CA  1 
ATOM   5815  C C   . MET B 1 141 ? 109.523 152.091 83.453  1.00 70.61  ? 141  MET B C   1 
ATOM   5816  O O   . MET B 1 141 ? 108.707 152.122 84.376  1.00 70.61  ? 141  MET B O   1 
ATOM   5817  C CB  . MET B 1 141 ? 111.113 150.519 84.532  1.00 70.61  ? 141  MET B CB  1 
ATOM   5818  C CG  . MET B 1 141 ? 112.163 149.433 84.430  1.00 70.61  ? 141  MET B CG  1 
ATOM   5819  S SD  . MET B 1 141 ? 113.195 149.409 85.906  1.00 70.61  ? 141  MET B SD  1 
ATOM   5820  C CE  . MET B 1 141 ? 113.782 151.102 85.934  1.00 70.61  ? 141  MET B CE  1 
ATOM   5821  N N   . ASP B 1 142 ? 109.729 153.138 82.649  1.00 67.55  ? 142  ASP B N   1 
ATOM   5822  C CA  . ASP B 1 142 ? 108.895 154.329 82.789  1.00 67.55  ? 142  ASP B CA  1 
ATOM   5823  C C   . ASP B 1 142 ? 107.541 154.156 82.117  1.00 67.55  ? 142  ASP B C   1 
ATOM   5824  O O   . ASP B 1 142 ? 106.553 154.749 82.562  1.00 67.55  ? 142  ASP B O   1 
ATOM   5825  C CB  . ASP B 1 142 ? 109.602 155.558 82.221  1.00 67.55  ? 142  ASP B CB  1 
ATOM   5826  C CG  . ASP B 1 142 ? 109.319 156.813 83.025  1.00 67.55  ? 142  ASP B CG  1 
ATOM   5827  O OD1 . ASP B 1 142 ? 108.610 156.718 84.050  1.00 67.55  ? 142  ASP B OD1 1 
ATOM   5828  O OD2 . ASP B 1 142 ? 109.810 157.893 82.636  1.00 67.55  ? 142  ASP B OD2 1 
ATOM   5829  N N   . ILE B 1 143 ? 107.468 153.372 81.039  1.00 63.34  ? 143  ILE B N   1 
ATOM   5830  C CA  . ILE B 1 143 ? 106.163 153.055 80.468  1.00 63.34  ? 143  ILE B CA  1 
ATOM   5831  C C   . ILE B 1 143 ? 105.442 152.056 81.367  1.00 63.34  ? 143  ILE B C   1 
ATOM   5832  O O   . ILE B 1 143 ? 104.206 151.986 81.373  1.00 63.34  ? 143  ILE B O   1 
ATOM   5833  C CB  . ILE B 1 143 ? 106.312 152.564 79.006  1.00 63.34  ? 143  ILE B CB  1 
ATOM   5834  C CG1 . ILE B 1 143 ? 104.960 152.538 78.284  1.00 63.34  ? 143  ILE B CG1 1 
ATOM   5835  C CG2 . ILE B 1 143 ? 106.985 151.200 78.927  1.00 63.34  ? 143  ILE B CG2 1 
ATOM   5836  C CD1 . ILE B 1 143 ? 105.072 152.450 76.778  1.00 63.34  ? 143  ILE B CD1 1 
ATOM   5837  N N   . LEU B 1 144 ? 106.200 151.291 82.161  1.00 63.06  ? 144  LEU B N   1 
ATOM   5838  C CA  . LEU B 1 144 ? 105.631 150.438 83.197  1.00 63.06  ? 144  LEU B CA  1 
ATOM   5839  C C   . LEU B 1 144 ? 104.914 151.256 84.263  1.00 63.06  ? 144  LEU B C   1 
ATOM   5840  O O   . LEU B 1 144 ? 103.882 150.820 84.785  1.00 63.06  ? 144  LEU B O   1 
ATOM   5841  C CB  . LEU B 1 144 ? 106.736 149.602 83.837  1.00 63.06  ? 144  LEU B CB  1 
ATOM   5842  C CG  . LEU B 1 144 ? 106.360 148.653 84.971  1.00 63.06  ? 144  LEU B CG  1 
ATOM   5843  C CD1 . LEU B 1 144 ? 105.570 147.444 84.472  1.00 63.06  ? 144  LEU B CD1 1 
ATOM   5844  C CD2 . LEU B 1 144 ? 107.591 148.269 85.780  1.00 63.06  ? 144  LEU B CD2 1 
ATOM   5845  N N   . ILE B 1 145 ? 105.454 152.437 84.589  1.00 67.99  ? 145  ILE B N   1 
ATOM   5846  C CA  . ILE B 1 145 ? 104.801 153.371 85.504  1.00 67.99  ? 145  ILE B CA  1 
ATOM   5847  C C   . ILE B 1 145 ? 103.429 153.779 84.983  1.00 67.99  ? 145  ILE B C   1 
ATOM   5848  O O   . ILE B 1 145 ? 102.479 153.886 85.767  1.00 67.99  ? 145  ILE B O   1 
ATOM   5849  C CB  . ILE B 1 145 ? 105.682 154.621 85.739  1.00 67.99  ? 145  ILE B CB  1 
ATOM   5850  C CG1 . ILE B 1 145 ? 107.103 154.253 86.182  1.00 67.99  ? 145  ILE B CG1 1 
ATOM   5851  C CG2 . ILE B 1 145 ? 105.069 155.556 86.779  1.00 67.99  ? 145  ILE B CG2 1 
ATOM   5852  C CD1 . ILE B 1 145 ? 107.195 153.275 87.340  1.00 67.99  ? 145  ILE B CD1 1 
ATOM   5853  N N   . GLU B 1 146 ? 103.290 153.961 83.667  1.00 65.96  ? 146  GLU B N   1 
ATOM   5854  C CA  . GLU B 1 146 ? 101.985 154.261 83.085  1.00 65.96  ? 146  GLU B CA  1 
ATOM   5855  C C   . GLU B 1 146 ? 101.065 153.047 83.157  1.00 65.96  ? 146  GLU B C   1 
ATOM   5856  O O   . GLU B 1 146 ? 99.841  153.188 83.272  1.00 65.96  ? 146  GLU B O   1 
ATOM   5857  C CB  . GLU B 1 146 ? 102.160 154.744 81.641  1.00 65.96  ? 146  GLU B CB  1 
ATOM   5858  C CG  . GLU B 1 146 ? 100.931 155.415 81.026  1.00 65.96  ? 146  GLU B CG  1 
ATOM   5859  C CD  . GLU B 1 146 ? 100.019 154.444 80.305  1.00 65.96  ? 146  GLU B CD  1 
ATOM   5860  O OE1 . GLU B 1 146 ? 100.535 153.441 79.773  1.00 65.96  ? 146  GLU B OE1 1 
ATOM   5861  O OE2 . GLU B 1 146 ? 98.793  154.678 80.273  1.00 65.96  ? 146  GLU B OE2 1 
ATOM   5862  N N   . LEU B 1 147 ? 101.637 151.842 83.111  1.00 63.07  ? 147  LEU B N   1 
ATOM   5863  C CA  . LEU B 1 147 ? 100.814 150.643 83.230  1.00 63.07  ? 147  LEU B CA  1 
ATOM   5864  C C   . LEU B 1 147 ? 100.501 150.321 84.686  1.00 63.07  ? 147  LEU B C   1 
ATOM   5865  O O   . LEU B 1 147 ? 99.349  150.024 85.024  1.00 63.07  ? 147  LEU B O   1 
ATOM   5866  C CB  . LEU B 1 147 ? 101.496 149.452 82.555  1.00 63.07  ? 147  LEU B CB  1 
ATOM   5867  C CG  . LEU B 1 147 ? 101.235 149.157 81.071  1.00 63.07  ? 147  LEU B CG  1 
ATOM   5868  C CD1 . LEU B 1 147 ? 99.776  148.763 80.863  1.00 63.07  ? 147  LEU B CD1 1 
ATOM   5869  C CD2 . LEU B 1 147 ? 101.624 150.293 80.132  1.00 63.07  ? 147  LEU B CD2 1 
ATOM   5870  N N   . LYS B 1 148 ? 101.504 150.380 85.565  1.00 66.42  ? 148  LYS B N   1 
ATOM   5871  C CA  . LYS B 1 148 ? 101.326 149.997 86.961  1.00 66.42  ? 148  LYS B CA  1 
ATOM   5872  C C   . LYS B 1 148 ? 100.633 151.073 87.795  1.00 66.42  ? 148  LYS B C   1 
ATOM   5873  O O   . LYS B 1 148 ? 100.445 150.884 88.999  1.00 66.42  ? 148  LYS B O   1 
ATOM   5874  C CB  . LYS B 1 148 ? 102.672 149.604 87.585  1.00 66.42  ? 148  LYS B CB  1 
ATOM   5875  C CG  . LYS B 1 148 ? 103.553 150.738 88.087  1.00 66.42  ? 148  LYS B CG  1 
ATOM   5876  C CD  . LYS B 1 148 ? 105.015 150.360 87.967  1.00 66.42  ? 148  LYS B CD  1 
ATOM   5877  C CE  . LYS B 1 148 ? 105.354 149.144 88.816  1.00 66.42  ? 148  LYS B CE  1 
ATOM   5878  N NZ  . LYS B 1 148 ? 106.814 149.045 89.083  1.00 66.42  ? 148  LYS B NZ  1 
ATOM   5879  N N   . ASP B 1 149 ? 100.238 152.189 87.189  1.00 67.20  ? 149  ASP B N   1 
ATOM   5880  C CA  . ASP B 1 149 ? 99.367  153.144 87.853  1.00 67.20  ? 149  ASP B CA  1 
ATOM   5881  C C   . ASP B 1 149 ? 97.894  152.938 87.533  1.00 67.20  ? 149  ASP B C   1 
ATOM   5882  O O   . ASP B 1 149 ? 97.052  153.196 88.398  1.00 67.20  ? 149  ASP B O   1 
ATOM   5883  C CB  . ASP B 1 149 ? 99.756  154.583 87.480  1.00 67.20  ? 149  ASP B CB  1 
ATOM   5884  C CG  . ASP B 1 149 ? 100.799 155.163 88.411  1.00 67.20  ? 149  ASP B CG  1 
ATOM   5885  O OD1 . ASP B 1 149 ? 100.828 156.399 88.573  1.00 67.20  ? 149  ASP B OD1 1 
ATOM   5886  O OD2 . ASP B 1 149 ? 101.592 154.383 88.985  1.00 67.20  ? 149  ASP B OD2 1 
ATOM   5887  N N   . ALA B 1 150 ? 97.566  152.471 86.327  1.00 68.04  ? 150  ALA B N   1 
ATOM   5888  C CA  . ALA B 1 150 ? 96.174  152.384 85.908  1.00 68.04  ? 150  ALA B CA  1 
ATOM   5889  C C   . ALA B 1 150 ? 95.558  151.011 86.132  1.00 68.04  ? 150  ALA B C   1 
ATOM   5890  O O   . ALA B 1 150 ? 94.390  150.819 85.781  1.00 68.04  ? 150  ALA B O   1 
ATOM   5891  C CB  . ALA B 1 150 ? 96.048  152.752 84.430  1.00 68.04  ? 150  ALA B CB  1 
ATOM   5892  N N   . PHE B 1 151 ? 96.300  150.051 86.698  1.00 67.48  ? 151  PHE B N   1 
ATOM   5893  C CA  . PHE B 1 151 ? 95.774  148.689 86.766  1.00 67.48  ? 151  PHE B CA  1 
ATOM   5894  C C   . PHE B 1 151 ? 94.748  148.547 87.885  1.00 67.48  ? 151  PHE B C   1 
ATOM   5895  O O   . PHE B 1 151 ? 93.954  147.599 87.888  1.00 67.48  ? 151  PHE B O   1 
ATOM   5896  C CB  . PHE B 1 151 ? 96.912  147.674 86.936  1.00 67.48  ? 151  PHE B CB  1 
ATOM   5897  C CG  . PHE B 1 151 ? 97.450  147.564 88.341  1.00 67.48  ? 151  PHE B CG  1 
ATOM   5898  C CD1 . PHE B 1 151 ? 98.346  148.490 88.832  1.00 67.48  ? 151  PHE B CD1 1 
ATOM   5899  C CD2 . PHE B 1 151 ? 97.108  146.478 89.143  1.00 67.48  ? 151  PHE B CD2 1 
ATOM   5900  C CE1 . PHE B 1 151 ? 98.855  148.377 90.122  1.00 67.48  ? 151  PHE B CE1 1 
ATOM   5901  C CE2 . PHE B 1 151 ? 97.611  146.351 90.430  1.00 67.48  ? 151  PHE B CE2 1 
ATOM   5902  C CZ  . PHE B 1 151 ? 98.486  147.304 90.914  1.00 67.48  ? 151  PHE B CZ  1 
ATOM   5903  N N   . LYS B 1 152 ? 94.755  149.469 88.849  1.00 64.31  ? 152  LYS B N   1 
ATOM   5904  C CA  . LYS B 1 152 ? 93.726  149.478 89.882  1.00 64.31  ? 152  LYS B CA  1 
ATOM   5905  C C   . LYS B 1 152 ? 92.761  150.645 89.724  1.00 64.31  ? 152  LYS B C   1 
ATOM   5906  O O   . LYS B 1 152 ? 91.655  150.599 90.274  1.00 64.31  ? 152  LYS B O   1 
ATOM   5907  C CB  . LYS B 1 152 ? 94.371  149.507 91.270  1.00 64.31  ? 152  LYS B CB  1 
ATOM   5908  C CG  . LYS B 1 152 ? 93.505  148.911 92.371  1.00 64.31  ? 152  LYS B CG  1 
ATOM   5909  C CD  . LYS B 1 152 ? 93.070  147.493 92.038  1.00 64.31  ? 152  LYS B CD  1 
ATOM   5910  C CE  . LYS B 1 152 ? 94.242  146.528 92.074  1.00 64.31  ? 152  LYS B CE  1 
ATOM   5911  N NZ  . LYS B 1 152 ? 93.781  145.130 92.269  1.00 64.31  ? 152  LYS B NZ  1 
ATOM   5912  N N   . GLN B 1 153 ? 93.155  151.683 88.984  1.00 65.94  ? 153  GLN B N   1 
ATOM   5913  C CA  . GLN B 1 153 ? 92.226  152.756 88.648  1.00 65.94  ? 153  GLN B CA  1 
ATOM   5914  C C   . GLN B 1 153 ? 91.170  152.255 87.668  1.00 65.94  ? 153  GLN B C   1 
ATOM   5915  O O   . GLN B 1 153 ? 89.966  152.435 87.889  1.00 65.94  ? 153  GLN B O   1 
ATOM   5916  C CB  . GLN B 1 153 ? 93.007  153.944 88.074  1.00 65.94  ? 153  GLN B CB  1 
ATOM   5917  C CG  . GLN B 1 153 ? 92.357  155.334 88.175  1.00 65.94  ? 153  GLN B CG  1 
ATOM   5918  C CD  . GLN B 1 153 ? 91.056  155.480 87.412  1.00 65.94  ? 153  GLN B CD  1 
ATOM   5919  O OE1 . GLN B 1 153 ? 90.976  155.152 86.228  1.00 65.94  ? 153  GLN B OE1 1 
ATOM   5920  N NE2 . GLN B 1 153 ? 90.025  155.962 88.091  1.00 65.94  ? 153  GLN B NE2 1 
ATOM   5921  N N   . LYS B 1 154 ? 91.603  151.626 86.577  1.00 61.29  ? 154  LYS B N   1 
ATOM   5922  C CA  . LYS B 1 154 ? 90.685  151.124 85.565  1.00 61.29  ? 154  LYS B CA  1 
ATOM   5923  C C   . LYS B 1 154 ? 90.013  149.815 85.960  1.00 61.29  ? 154  LYS B C   1 
ATOM   5924  O O   . LYS B 1 154 ? 89.018  149.438 85.331  1.00 61.29  ? 154  LYS B O   1 
ATOM   5925  C CB  . LYS B 1 154 ? 91.415  150.947 84.225  1.00 61.29  ? 154  LYS B CB  1 
ATOM   5926  C CG  . LYS B 1 154 ? 91.937  152.246 83.592  1.00 61.29  ? 154  LYS B CG  1 
ATOM   5927  C CD  . LYS B 1 154 ? 90.863  153.314 83.320  1.00 61.29  ? 154  LYS B CD  1 
ATOM   5928  C CE  . LYS B 1 154 ? 89.655  152.791 82.533  1.00 61.29  ? 154  LYS B CE  1 
ATOM   5929  N NZ  . LYS B 1 154 ? 88.787  153.898 82.051  1.00 61.29  ? 154  LYS B NZ  1 
ATOM   5930  N N   . GLN B 1 155 ? 90.532  149.111 86.971  1.00 65.67  ? 155  GLN B N   1 
ATOM   5931  C CA  . GLN B 1 155 ? 89.804  147.970 87.518  1.00 65.67  ? 155  GLN B CA  1 
ATOM   5932  C C   . GLN B 1 155 ? 88.556  148.436 88.251  1.00 65.67  ? 155  GLN B C   1 
ATOM   5933  O O   . GLN B 1 155 ? 87.534  147.741 88.264  1.00 65.67  ? 155  GLN B O   1 
ATOM   5934  C CB  . GLN B 1 155 ? 90.706  147.160 88.447  1.00 65.67  ? 155  GLN B CB  1 
ATOM   5935  C CG  . GLN B 1 155 ? 90.142  145.805 88.840  1.00 65.67  ? 155  GLN B CG  1 
ATOM   5936  C CD  . GLN B 1 155 ? 91.179  144.908 89.482  1.00 65.67  ? 155  GLN B CD  1 
ATOM   5937  O OE1 . GLN B 1 155 ? 92.333  145.298 89.651  1.00 65.67  ? 155  GLN B OE1 1 
ATOM   5938  N NE2 . GLN B 1 155 ? 90.773  143.698 89.846  1.00 65.67  ? 155  GLN B NE2 1 
ATOM   5939  N N   . ALA B 1 156 ? 88.618  149.626 88.846  1.00 60.68  ? 156  ALA B N   1 
ATOM   5940  C CA  . ALA B 1 156 ? 87.448  150.254 89.436  1.00 60.68  ? 156  ALA B CA  1 
ATOM   5941  C C   . ALA B 1 156 ? 86.520  150.866 88.394  1.00 60.68  ? 156  ALA B C   1 
ATOM   5942  O O   . ALA B 1 156 ? 85.384  151.215 88.729  1.00 60.68  ? 156  ALA B O   1 
ATOM   5943  C CB  . ALA B 1 156 ? 87.886  151.328 90.432  1.00 60.68  ? 156  ALA B CB  1 
ATOM   5944  N N   . ASN B 1 157 ? 86.971  151.006 87.152  1.00 62.72  ? 157  ASN B N   1 
ATOM   5945  C CA  . ASN B 1 157 ? 86.137  151.564 86.096  1.00 62.72  ? 157  ASN B CA  1 
ATOM   5946  C C   . ASN B 1 157 ? 85.600  150.461 85.189  1.00 62.72  ? 157  ASN B C   1 
ATOM   5947  O O   . ASN B 1 157 ? 85.180  150.721 84.061  1.00 62.72  ? 157  ASN B O   1 
ATOM   5948  C CB  . ASN B 1 157 ? 86.924  152.585 85.274  1.00 62.72  ? 157  ASN B CB  1 
ATOM   5949  C CG  . ASN B 1 157 ? 87.256  153.834 86.063  1.00 62.72  ? 157  ASN B CG  1 
ATOM   5950  O OD1 . ASN B 1 157 ? 86.431  154.343 86.822  1.00 62.72  ? 157  ASN B OD1 1 
ATOM   5951  N ND2 . ASN B 1 157 ? 88.470  154.337 85.885  1.00 62.72  ? 157  ASN B ND2 1 
ATOM   5952  N N   . LYS B 1 280 ? 94.484  142.584 78.924  1.00 67.32  ? 280  LYS B N   1 
ATOM   5953  C CA  . LYS B 1 280 ? 95.034  141.366 79.508  1.00 67.32  ? 280  LYS B CA  1 
ATOM   5954  C C   . LYS B 1 280 ? 96.537  141.296 79.267  1.00 67.32  ? 280  LYS B C   1 
ATOM   5955  O O   . LYS B 1 280 ? 97.176  140.281 79.541  1.00 67.32  ? 280  LYS B O   1 
ATOM   5956  C CB  . LYS B 1 280 ? 94.346  140.124 78.928  1.00 67.32  ? 280  LYS B CB  1 
ATOM   5957  C CG  . LYS B 1 280 ? 92.862  139.952 79.277  1.00 67.32  ? 280  LYS B CG  1 
ATOM   5958  C CD  . LYS B 1 280 ? 92.481  140.518 80.643  1.00 67.32  ? 280  LYS B CD  1 
ATOM   5959  C CE  . LYS B 1 280 ? 90.983  140.412 80.879  1.00 67.32  ? 280  LYS B CE  1 
ATOM   5960  N NZ  . LYS B 1 280 ? 90.555  141.128 82.111  1.00 67.32  ? 280  LYS B NZ  1 
ATOM   5961  N N   . LYS B 1 281 ? 97.097  142.390 78.753  1.00 66.21  ? 281  LYS B N   1 
ATOM   5962  C CA  . LYS B 1 281 ? 98.527  142.496 78.492  1.00 66.21  ? 281  LYS B CA  1 
ATOM   5963  C C   . LYS B 1 281 ? 99.331  142.844 79.736  1.00 66.21  ? 281  LYS B C   1 
ATOM   5964  O O   . LYS B 1 281 ? 100.556 142.984 79.644  1.00 66.21  ? 281  LYS B O   1 
ATOM   5965  C CB  . LYS B 1 281 ? 98.786  143.543 77.405  1.00 66.21  ? 281  LYS B CB  1 
ATOM   5966  C CG  . LYS B 1 281 ? 98.378  144.954 77.796  1.00 66.21  ? 281  LYS B CG  1 
ATOM   5967  C CD  . LYS B 1 281 ? 99.032  145.989 76.893  1.00 66.21  ? 281  LYS B CD  1 
ATOM   5968  C CE  . LYS B 1 281 ? 98.160  147.226 76.748  1.00 66.21  ? 281  LYS B CE  1 
ATOM   5969  N NZ  . LYS B 1 281 ? 97.177  147.081 75.637  1.00 66.21  ? 281  LYS B NZ  1 
ATOM   5970  N N   . LEU B 1 282 ? 98.670  142.998 80.886  1.00 63.90  ? 282  LEU B N   1 
ATOM   5971  C CA  . LEU B 1 282 ? 99.366  143.306 82.130  1.00 63.90  ? 282  LEU B CA  1 
ATOM   5972  C C   . LEU B 1 282 ? 100.235 142.137 82.579  1.00 63.90  ? 282  LEU B C   1 
ATOM   5973  O O   . LEU B 1 282 ? 101.326 142.335 83.126  1.00 63.90  ? 282  LEU B O   1 
ATOM   5974  C CB  . LEU B 1 282 ? 98.343  143.697 83.204  1.00 63.90  ? 282  LEU B CB  1 
ATOM   5975  C CG  . LEU B 1 282 ? 97.187  142.754 83.578  1.00 63.90  ? 282  LEU B CG  1 
ATOM   5976  C CD1 . LEU B 1 282 ? 97.516  141.808 84.735  1.00 63.90  ? 282  LEU B CD1 1 
ATOM   5977  C CD2 . LEU B 1 282 ? 95.924  143.548 83.878  1.00 63.90  ? 282  LEU B CD2 1 
ATOM   5978  N N   . SER B 1 283 ? 99.770  140.909 82.347  1.00 61.61  ? 283  SER B N   1 
ATOM   5979  C CA  . SER B 1 283 ? 100.572 139.740 82.675  1.00 61.61  ? 283  SER B CA  1 
ATOM   5980  C C   . SER B 1 283 ? 101.662 139.489 81.643  1.00 61.61  ? 283  SER B C   1 
ATOM   5981  O O   . SER B 1 283 ? 102.698 138.910 81.984  1.00 61.61  ? 283  SER B O   1 
ATOM   5982  C CB  . SER B 1 283 ? 99.672  138.513 82.810  1.00 61.61  ? 283  SER B CB  1 
ATOM   5983  O OG  . SER B 1 283 ? 98.686  138.722 83.805  1.00 61.61  ? 283  SER B OG  1 
ATOM   5984  N N   . HIS B 1 284 ? 101.452 139.915 80.394  1.00 68.23  ? 284  HIS B N   1 
ATOM   5985  C CA  . HIS B 1 284 ? 102.521 139.862 79.402  1.00 68.23  ? 284  HIS B CA  1 
ATOM   5986  C C   . HIS B 1 284 ? 103.599 140.887 79.729  1.00 68.23  ? 284  HIS B C   1 
ATOM   5987  O O   . HIS B 1 284 ? 104.777 140.686 79.410  1.00 68.23  ? 284  HIS B O   1 
ATOM   5988  C CB  . HIS B 1 284 ? 101.928 140.072 77.999  1.00 68.23  ? 284  HIS B CB  1 
ATOM   5989  C CG  . HIS B 1 284 ? 102.937 140.134 76.885  1.00 68.23  ? 284  HIS B CG  1 
ATOM   5990  N ND1 . HIS B 1 284 ? 103.054 139.135 75.942  1.00 68.23  ? 284  HIS B ND1 1 
ATOM   5991  C CD2 . HIS B 1 284 ? 103.796 141.110 76.500  1.00 68.23  ? 284  HIS B CD2 1 
ATOM   5992  C CE1 . HIS B 1 284 ? 103.987 139.462 75.066  1.00 68.23  ? 284  HIS B CE1 1 
ATOM   5993  N NE2 . HIS B 1 284 ? 104.454 140.657 75.382  1.00 68.23  ? 284  HIS B NE2 1 
ATOM   5994  N N   . ALA B 1 285 ? 103.218 141.977 80.395  1.00 66.75  ? 285  ALA B N   1 
ATOM   5995  C CA  . ALA B 1 285 ? 104.160 143.011 80.795  1.00 66.75  ? 285  ALA B CA  1 
ATOM   5996  C C   . ALA B 1 285 ? 105.128 142.555 81.877  1.00 66.75  ? 285  ALA B C   1 
ATOM   5997  O O   . ALA B 1 285 ? 106.186 143.173 82.028  1.00 66.75  ? 285  ALA B O   1 
ATOM   5998  C CB  . ALA B 1 285 ? 103.401 144.248 81.280  1.00 66.75  ? 285  ALA B CB  1 
ATOM   5999  N N   . GLU B 1 286 ? 104.802 141.496 82.621  1.00 68.38  ? 286  GLU B N   1 
ATOM   6000  C CA  . GLU B 1 286 ? 105.672 141.054 83.706  1.00 68.38  ? 286  GLU B CA  1 
ATOM   6001  C C   . GLU B 1 286 ? 106.938 140.395 83.168  1.00 68.38  ? 286  GLU B C   1 
ATOM   6002  O O   . GLU B 1 286 ? 108.048 140.759 83.567  1.00 68.38  ? 286  GLU B O   1 
ATOM   6003  C CB  . GLU B 1 286 ? 104.905 140.109 84.632  1.00 68.38  ? 286  GLU B CB  1 
ATOM   6004  C CG  . GLU B 1 286 ? 103.488 140.582 84.930  1.00 68.38  ? 286  GLU B CG  1 
ATOM   6005  C CD  . GLU B 1 286 ? 102.672 139.572 85.715  1.00 68.38  ? 286  GLU B CD  1 
ATOM   6006  O OE1 . GLU B 1 286 ? 101.564 139.928 86.167  1.00 68.38  ? 286  GLU B OE1 1 
ATOM   6007  O OE2 . GLU B 1 286 ? 103.134 138.425 85.880  1.00 68.38  ? 286  GLU B OE2 1 
ATOM   6008  N N   . LYS B 1 287 ? 106.788 139.461 82.219  1.00 66.05  ? 287  LYS B N   1 
ATOM   6009  C CA  . LYS B 1 287 ? 107.934 138.800 81.587  1.00 66.05  ? 287  LYS B CA  1 
ATOM   6010  C C   . LYS B 1 287 ? 108.788 139.802 80.807  1.00 66.05  ? 287  LYS B C   1 
ATOM   6011  O O   . LYS B 1 287 ? 109.999 139.607 80.648  1.00 66.05  ? 287  LYS B O   1 
ATOM   6012  C CB  . LYS B 1 287 ? 107.421 137.672 80.680  1.00 66.05  ? 287  LYS B CB  1 
ATOM   6013  C CG  . LYS B 1 287 ? 108.417 136.903 79.774  1.00 66.05  ? 287  LYS B CG  1 
ATOM   6014  C CD  . LYS B 1 287 ? 109.700 136.416 80.453  1.00 66.05  ? 287  LYS B CD  1 
ATOM   6015  C CE  . LYS B 1 287 ? 110.367 135.335 79.606  1.00 66.05  ? 287  LYS B CE  1 
ATOM   6016  N NZ  . LYS B 1 287 ? 111.594 134.769 80.229  1.00 66.05  ? 287  LYS B NZ  1 
ATOM   6017  N N   . MET B 1 288 ? 108.181 140.908 80.361  1.00 66.72  ? 288  MET B N   1 
ATOM   6018  C CA  . MET B 1 288 ? 108.942 141.981 79.730  1.00 66.72  ? 288  MET B CA  1 
ATOM   6019  C C   . MET B 1 288 ? 109.919 142.642 80.698  1.00 66.72  ? 288  MET B C   1 
ATOM   6020  O O   . MET B 1 288 ? 110.906 143.242 80.258  1.00 66.72  ? 288  MET B O   1 
ATOM   6021  C CB  . MET B 1 288 ? 107.994 143.038 79.164  1.00 66.72  ? 288  MET B CB  1 
ATOM   6022  C CG  . MET B 1 288 ? 107.122 142.567 78.014  1.00 66.72  ? 288  MET B CG  1 
ATOM   6023  S SD  . MET B 1 288 ? 108.077 142.003 76.592  1.00 66.72  ? 288  MET B SD  1 
ATOM   6024  C CE  . MET B 1 288 ? 108.820 143.550 76.067  1.00 66.72  ? 288  MET B CE  1 
ATOM   6025  N N   . ILE B 1 289 ? 109.667 142.555 82.007  1.00 63.24  ? 289  ILE B N   1 
ATOM   6026  C CA  . ILE B 1 289 ? 110.589 143.133 82.978  1.00 63.24  ? 289  ILE B CA  1 
ATOM   6027  C C   . ILE B 1 289 ? 111.141 142.125 83.983  1.00 63.24  ? 289  ILE B C   1 
ATOM   6028  O O   . ILE B 1 289 ? 112.144 142.426 84.645  1.00 63.24  ? 289  ILE B O   1 
ATOM   6029  C CB  . ILE B 1 289 ? 109.930 144.299 83.733  1.00 63.24  ? 289  ILE B CB  1 
ATOM   6030  C CG1 . ILE B 1 289 ? 108.527 143.907 84.187  1.00 63.24  ? 289  ILE B CG1 1 
ATOM   6031  C CG2 . ILE B 1 289 ? 109.895 145.548 82.858  1.00 63.24  ? 289  ILE B CG2 1 
ATOM   6032  C CD1 . ILE B 1 289 ? 108.033 144.641 85.390  1.00 63.24  ? 289  ILE B CD1 1 
ATOM   6033  N N   . LYS B 1 290 ? 110.505 140.959 84.142  1.00 60.63  ? 290  LYS B N   1 
ATOM   6034  C CA  . LYS B 1 290 ? 111.086 139.907 84.975  1.00 60.63  ? 290  LYS B CA  1 
ATOM   6035  C C   . LYS B 1 290 ? 112.399 139.413 84.388  1.00 60.63  ? 290  LYS B C   1 
ATOM   6036  O O   . LYS B 1 290 ? 113.469 139.622 84.969  1.00 60.63  ? 290  LYS B O   1 
ATOM   6037  C CB  . LYS B 1 290 ? 110.116 138.733 85.140  1.00 60.63  ? 290  LYS B CB  1 
ATOM   6038  C CG  . LYS B 1 290 ? 108.930 138.969 86.058  1.00 60.63  ? 290  LYS B CG  1 
ATOM   6039  C CD  . LYS B 1 290 ? 108.483 137.671 86.704  1.00 60.63  ? 290  LYS B CD  1 
ATOM   6040  C CE  . LYS B 1 290 ? 106.969 137.554 86.705  1.00 60.63  ? 290  LYS B CE  1 
ATOM   6041  N NZ  . LYS B 1 290 ? 106.523 136.135 86.704  1.00 60.63  ? 290  LYS B NZ  1 
ATOM   6042  N N   . GLY B 1 291 ? 112.335 138.795 83.205  1.00 58.61  ? 291  GLY B N   1 
ATOM   6043  C CA  . GLY B 1 291 ? 113.515 138.245 82.559  1.00 58.61  ? 291  GLY B CA  1 
ATOM   6044  C C   . GLY B 1 291 ? 114.550 139.275 82.167  1.00 58.61  ? 291  GLY B C   1 
ATOM   6045  O O   . GLY B 1 291 ? 115.722 138.925 81.996  1.00 58.61  ? 291  GLY B O   1 
ATOM   6046  N N   . ALA B 1 292 ? 114.146 140.537 82.026  1.00 57.81  ? 292  ALA B N   1 
ATOM   6047  C CA  . ALA B 1 292 ? 115.116 141.606 81.837  1.00 57.81  ? 292  ALA B CA  1 
ATOM   6048  C C   . ALA B 1 292 ? 115.957 141.799 83.092  1.00 57.81  ? 292  ALA B C   1 
ATOM   6049  O O   . ALA B 1 292 ? 117.167 141.557 83.087  1.00 57.81  ? 292  ALA B O   1 
ATOM   6050  C CB  . ALA B 1 292 ? 114.398 142.905 81.463  1.00 57.81  ? 292  ALA B CB  1 
ATOM   6051  N N   . LEU B 1 293 ? 115.316 142.166 84.197  1.00 56.85  ? 293  LEU B N   1 
ATOM   6052  C CA  . LEU B 1 293 ? 116.051 142.596 85.379  1.00 56.85  ? 293  LEU B CA  1 
ATOM   6053  C C   . LEU B 1 293 ? 116.435 141.456 86.314  1.00 56.85  ? 293  LEU B C   1 
ATOM   6054  O O   . LEU B 1 293 ? 116.940 141.727 87.407  1.00 56.85  ? 293  LEU B O   1 
ATOM   6055  C CB  . LEU B 1 293 ? 115.248 143.647 86.151  1.00 56.85  ? 293  LEU B CB  1 
ATOM   6056  C CG  . LEU B 1 293 ? 115.464 145.131 85.815  1.00 56.85  ? 293  LEU B CG  1 
ATOM   6057  C CD1 . LEU B 1 293 ? 116.896 145.540 86.122  1.00 56.85  ? 293  LEU B CD1 1 
ATOM   6058  C CD2 . LEU B 1 293 ? 115.101 145.495 84.380  1.00 56.85  ? 293  LEU B CD2 1 
ATOM   6059  N N   . THR B 1 294 ? 116.219 140.199 85.931  1.00 54.09  ? 294  THR B N   1 
ATOM   6060  C CA  . THR B 1 294 ? 116.779 139.102 86.714  1.00 54.09  ? 294  THR B CA  1 
ATOM   6061  C C   . THR B 1 294 ? 118.284 138.976 86.492  1.00 54.09  ? 294  THR B C   1 
ATOM   6062  O O   . THR B 1 294 ? 119.076 139.114 87.430  1.00 54.09  ? 294  THR B O   1 
ATOM   6063  C CB  . THR B 1 294 ? 116.057 137.794 86.386  1.00 54.09  ? 294  THR B CB  1 
ATOM   6064  O OG1 . THR B 1 294 ? 115.824 137.716 84.975  1.00 54.09  ? 294  THR B OG1 1 
ATOM   6065  C CG2 . THR B 1 294 ? 114.759 137.656 87.172  1.00 54.09  ? 294  THR B CG2 1 
ATOM   6066  N N   . GLU B 1 295 ? 118.702 138.728 85.255  1.00 55.72  ? 295  GLU B N   1 
ATOM   6067  C CA  . GLU B 1 295 ? 120.121 138.559 84.968  1.00 55.72  ? 295  GLU B CA  1 
ATOM   6068  C C   . GLU B 1 295 ? 120.837 139.877 84.722  1.00 55.72  ? 295  GLU B C   1 
ATOM   6069  O O   . GLU B 1 295 ? 122.073 139.894 84.689  1.00 55.72  ? 295  GLU B O   1 
ATOM   6070  C CB  . GLU B 1 295 ? 120.316 137.642 83.755  1.00 55.72  ? 295  GLU B CB  1 
ATOM   6071  C CG  . GLU B 1 295 ? 120.239 136.155 84.068  1.00 55.72  ? 295  GLU B CG  1 
ATOM   6072  C CD  . GLU B 1 295 ? 119.552 135.366 82.969  1.00 55.72  ? 295  GLU B CD  1 
ATOM   6073  O OE1 . GLU B 1 295 ? 120.103 135.287 81.852  1.00 55.72  ? 295  GLU B OE1 1 
ATOM   6074  O OE2 . GLU B 1 295 ? 118.465 134.812 83.223  1.00 55.72  ? 295  GLU B OE2 1 
ATOM   6075  N N   . LEU B 1 296 ? 120.097 140.974 84.543  1.00 54.21  ? 296  LEU B N   1 
ATOM   6076  C CA  . LEU B 1 296 ? 120.733 142.284 84.464  1.00 54.21  ? 296  LEU B CA  1 
ATOM   6077  C C   . LEU B 1 296 ? 121.318 142.678 85.811  1.00 54.21  ? 296  LEU B C   1 
ATOM   6078  O O   . LEU B 1 296 ? 122.329 143.387 85.871  1.00 54.21  ? 296  LEU B O   1 
ATOM   6079  C CB  . LEU B 1 296 ? 119.725 143.319 83.972  1.00 54.21  ? 296  LEU B CB  1 
ATOM   6080  C CG  . LEU B 1 296 ? 120.062 144.799 83.799  1.00 54.21  ? 296  LEU B CG  1 
ATOM   6081  C CD1 . LEU B 1 296 ? 121.404 145.010 83.141  1.00 54.21  ? 296  LEU B CD1 1 
ATOM   6082  C CD2 . LEU B 1 296 ? 118.985 145.391 82.933  1.00 54.21  ? 296  LEU B CD2 1 
ATOM   6083  N N   . PHE B 1 297 ? 120.695 142.226 86.902  1.00 57.13  ? 297  PHE B N   1 
ATOM   6084  C CA  . PHE B 1 297 ? 121.367 142.264 88.194  1.00 57.13  ? 297  PHE B CA  1 
ATOM   6085  C C   . PHE B 1 297 ? 122.610 141.387 88.171  1.00 57.13  ? 297  PHE B C   1 
ATOM   6086  O O   . PHE B 1 297 ? 123.683 141.814 88.610  1.00 57.13  ? 297  PHE B O   1 
ATOM   6087  C CB  . PHE B 1 297 ? 120.422 141.798 89.303  1.00 57.13  ? 297  PHE B CB  1 
ATOM   6088  C CG  . PHE B 1 297 ? 120.967 141.984 90.701  1.00 57.13  ? 297  PHE B CG  1 
ATOM   6089  C CD1 . PHE B 1 297 ? 120.505 141.194 91.738  1.00 57.13  ? 297  PHE B CD1 1 
ATOM   6090  C CD2 . PHE B 1 297 ? 121.881 142.989 90.995  1.00 57.13  ? 297  PHE B CD2 1 
ATOM   6091  C CE1 . PHE B 1 297 ? 120.978 141.355 93.025  1.00 57.13  ? 297  PHE B CE1 1 
ATOM   6092  C CE2 . PHE B 1 297 ? 122.362 143.158 92.283  1.00 57.13  ? 297  PHE B CE2 1 
ATOM   6093  C CZ  . PHE B 1 297 ? 121.905 142.341 93.299  1.00 57.13  ? 297  PHE B CZ  1 
ATOM   6094  N N   . LYS B 1 298 ? 122.493 140.171 87.631  1.00 53.28  ? 298  LYS B N   1 
ATOM   6095  C CA  . LYS B 1 298 ? 123.618 139.247 87.673  1.00 53.28  ? 298  LYS B CA  1 
ATOM   6096  C C   . LYS B 1 298 ? 124.721 139.648 86.708  1.00 53.28  ? 298  LYS B C   1 
ATOM   6097  O O   . LYS B 1 298 ? 125.856 139.192 86.858  1.00 53.28  ? 298  LYS B O   1 
ATOM   6098  C CB  . LYS B 1 298 ? 123.144 137.819 87.400  1.00 53.28  ? 298  LYS B CB  1 
ATOM   6099  C CG  . LYS B 1 298 ? 122.554 137.096 88.623  1.00 53.28  ? 298  LYS B CG  1 
ATOM   6100  C CD  . LYS B 1 298 ? 123.182 137.573 89.935  1.00 53.28  ? 298  LYS B CD  1 
ATOM   6101  C CE  . LYS B 1 298 ? 122.839 136.699 91.120  1.00 53.28  ? 298  LYS B CE  1 
ATOM   6102  N NZ  . LYS B 1 298 ? 123.487 137.180 92.374  1.00 53.28  ? 298  LYS B NZ  1 
ATOM   6103  N N   . GLY B 1 299 ? 124.420 140.507 85.733  1.00 49.94  ? 299  GLY B N   1 
ATOM   6104  C CA  . GLY B 1 299 ? 125.483 141.137 84.974  1.00 49.94  ? 299  GLY B CA  1 
ATOM   6105  C C   . GLY B 1 299 ? 126.316 142.076 85.819  1.00 49.94  ? 299  GLY B C   1 
ATOM   6106  O O   . GLY B 1 299 ? 127.511 142.254 85.564  1.00 49.94  ? 299  GLY B O   1 
ATOM   6107  N N   . LEU B 1 300 ? 125.702 142.686 86.833  1.00 49.72  ? 300  LEU B N   1 
ATOM   6108  C CA  . LEU B 1 300 ? 126.443 143.508 87.779  1.00 49.72  ? 300  LEU B CA  1 
ATOM   6109  C C   . LEU B 1 300 ? 127.132 142.663 88.843  1.00 49.72  ? 300  LEU B C   1 
ATOM   6110  O O   . LEU B 1 300 ? 128.255 142.985 89.242  1.00 49.72  ? 300  LEU B O   1 
ATOM   6111  C CB  . LEU B 1 300 ? 125.501 144.524 88.424  1.00 49.72  ? 300  LEU B CB  1 
ATOM   6112  C CG  . LEU B 1 300 ? 124.612 145.275 87.428  1.00 49.72  ? 300  LEU B CG  1 
ATOM   6113  C CD1 . LEU B 1 300 ? 123.596 146.160 88.126  1.00 49.72  ? 300  LEU B CD1 1 
ATOM   6114  C CD2 . LEU B 1 300 ? 125.464 146.102 86.495  1.00 49.72  ? 300  LEU B CD2 1 
ATOM   6115  N N   . ASN B 1 301 ? 126.484 141.587 89.312  1.00 53.45  ? 301  ASN B N   1 
ATOM   6116  C CA  . ASN B 1 301 ? 127.152 140.657 90.223  1.00 53.45  ? 301  ASN B CA  1 
ATOM   6117  C C   . ASN B 1 301 ? 128.307 139.929 89.552  1.00 53.45  ? 301  ASN B C   1 
ATOM   6118  O O   . ASN B 1 301 ? 129.250 139.518 90.235  1.00 53.45  ? 301  ASN B O   1 
ATOM   6119  C CB  . ASN B 1 301 ? 126.165 139.640 90.804  1.00 53.45  ? 301  ASN B CB  1 
ATOM   6120  C CG  . ASN B 1 301 ? 125.047 140.287 91.608  1.00 53.45  ? 301  ASN B CG  1 
ATOM   6121  O OD1 . ASN B 1 301 ? 123.952 140.517 91.104  1.00 53.45  ? 301  ASN B OD1 1 
ATOM   6122  N ND2 . ASN B 1 301 ? 125.318 140.561 92.878  1.00 53.45  ? 301  ASN B ND2 1 
ATOM   6123  N N   . TYR B 1 302 ? 128.249 139.738 88.232  1.00 54.61  ? 302  TYR B N   1 
ATOM   6124  C CA  . TYR B 1 302 ? 129.440 139.288 87.520  1.00 54.61  ? 302  TYR B CA  1 
ATOM   6125  C C   . TYR B 1 302 ? 130.487 140.392 87.485  1.00 54.61  ? 302  TYR B C   1 
ATOM   6126  O O   . TYR B 1 302 ? 131.689 140.120 87.583  1.00 54.61  ? 302  TYR B O   1 
ATOM   6127  C CB  . TYR B 1 302 ? 129.092 138.843 86.095  1.00 54.61  ? 302  TYR B CB  1 
ATOM   6128  C CG  . TYR B 1 302 ? 128.246 137.584 85.978  1.00 54.61  ? 302  TYR B CG  1 
ATOM   6129  C CD1 . TYR B 1 302 ? 128.090 136.713 87.050  1.00 54.61  ? 302  TYR B CD1 1 
ATOM   6130  C CD2 . TYR B 1 302 ? 127.584 137.284 84.791  1.00 54.61  ? 302  TYR B CD2 1 
ATOM   6131  C CE1 . TYR B 1 302 ? 127.310 135.576 86.940  1.00 54.61  ? 302  TYR B CE1 1 
ATOM   6132  C CE2 . TYR B 1 302 ? 126.806 136.150 84.672  1.00 54.61  ? 302  TYR B CE2 1 
ATOM   6133  C CZ  . TYR B 1 302 ? 126.673 135.301 85.749  1.00 54.61  ? 302  TYR B CZ  1 
ATOM   6134  O OH  . TYR B 1 302 ? 125.898 134.172 85.633  1.00 54.61  ? 302  TYR B OH  1 
ATOM   6135  N N   . LEU B 1 303 ? 130.045 141.645 87.364  1.00 52.52  ? 303  LEU B N   1 
ATOM   6136  C CA  . LEU B 1 303 ? 130.972 142.766 87.290  1.00 52.52  ? 303  LEU B CA  1 
ATOM   6137  C C   . LEU B 1 303 ? 131.636 143.052 88.628  1.00 52.52  ? 303  LEU B C   1 
ATOM   6138  O O   . LEU B 1 303 ? 132.790 143.493 88.657  1.00 52.52  ? 303  LEU B O   1 
ATOM   6139  C CB  . LEU B 1 303 ? 130.246 144.010 86.780  1.00 52.52  ? 303  LEU B CB  1 
ATOM   6140  C CG  . LEU B 1 303 ? 131.103 145.178 86.282  1.00 52.52  ? 303  LEU B CG  1 
ATOM   6141  C CD1 . LEU B 1 303 ? 132.334 144.704 85.513  1.00 52.52  ? 303  LEU B CD1 1 
ATOM   6142  C CD2 . LEU B 1 303 ? 130.258 146.095 85.420  1.00 52.52  ? 303  LEU B CD2 1 
ATOM   6143  N N   . LYS B 1 304 ? 130.932 142.824 89.738  1.00 51.99  ? 304  LYS B N   1 
ATOM   6144  C CA  . LYS B 1 304 ? 131.595 142.861 91.036  1.00 51.99  ? 304  LYS B CA  1 
ATOM   6145  C C   . LYS B 1 304 ? 132.561 141.694 91.176  1.00 51.99  ? 304  LYS B C   1 
ATOM   6146  O O   . LYS B 1 304 ? 133.673 141.859 91.690  1.00 51.99  ? 304  LYS B O   1 
ATOM   6147  C CB  . LYS B 1 304 ? 130.563 142.837 92.163  1.00 51.99  ? 304  LYS B CB  1 
ATOM   6148  C CG  . LYS B 1 304 ? 129.525 143.938 92.090  1.00 51.99  ? 304  LYS B CG  1 
ATOM   6149  C CD  . LYS B 1 304 ? 128.168 143.449 92.558  1.00 51.99  ? 304  LYS B CD  1 
ATOM   6150  C CE  . LYS B 1 304 ? 127.074 144.422 92.169  1.00 51.99  ? 304  LYS B CE  1 
ATOM   6151  N NZ  . LYS B 1 304 ? 125.738 143.953 92.615  1.00 51.99  ? 304  LYS B NZ  1 
ATOM   6152  N N   . THR B 1 305 ? 132.154 140.511 90.702  1.00 52.68  ? 305  THR B N   1 
ATOM   6153  C CA  . THR B 1 305 ? 133.042 139.355 90.688  1.00 52.68  ? 305  THR B CA  1 
ATOM   6154  C C   . THR B 1 305 ? 134.191 139.566 89.712  1.00 52.68  ? 305  THR B C   1 
ATOM   6155  O O   . THR B 1 305 ? 135.291 139.044 89.924  1.00 52.68  ? 305  THR B O   1 
ATOM   6156  C CB  . THR B 1 305 ? 132.246 138.099 90.328  1.00 52.68  ? 305  THR B CB  1 
ATOM   6157  O OG1 . THR B 1 305 ? 131.034 138.075 91.091  1.00 52.68  ? 305  THR B OG1 1 
ATOM   6158  C CG2 . THR B 1 305 ? 133.030 136.840 90.657  1.00 52.68  ? 305  THR B CG2 1 
ATOM   6159  N N   . TYR B 1 306 ? 133.956 140.343 88.652  1.00 50.26  ? 306  TYR B N   1 
ATOM   6160  C CA  . TYR B 1 306 ? 135.051 140.792 87.801  1.00 50.26  ? 306  TYR B CA  1 
ATOM   6161  C C   . TYR B 1 306 ? 136.011 141.686 88.574  1.00 50.26  ? 306  TYR B C   1 
ATOM   6162  O O   . TYR B 1 306 ? 137.230 141.583 88.410  1.00 50.26  ? 306  TYR B O   1 
ATOM   6163  C CB  . TYR B 1 306 ? 134.492 141.525 86.582  1.00 50.26  ? 306  TYR B CB  1 
ATOM   6164  C CG  . TYR B 1 306 ? 135.532 142.140 85.678  1.00 50.26  ? 306  TYR B CG  1 
ATOM   6165  C CD1 . TYR B 1 306 ? 135.853 143.491 85.765  1.00 50.26  ? 306  TYR B CD1 1 
ATOM   6166  C CD2 . TYR B 1 306 ? 136.175 141.377 84.723  1.00 50.26  ? 306  TYR B CD2 1 
ATOM   6167  C CE1 . TYR B 1 306 ? 136.802 144.052 84.939  1.00 50.26  ? 306  TYR B CE1 1 
ATOM   6168  C CE2 . TYR B 1 306 ? 137.117 141.931 83.889  1.00 50.26  ? 306  TYR B CE2 1 
ATOM   6169  C CZ  . TYR B 1 306 ? 137.433 143.266 84.005  1.00 50.26  ? 306  TYR B CZ  1 
ATOM   6170  O OH  . TYR B 1 306 ? 138.374 143.813 83.167  1.00 50.26  ? 306  TYR B OH  1 
ATOM   6171  N N   . ARG B 1 307 ? 135.475 142.568 89.424  1.00 52.72  ? 307  ARG B N   1 
ATOM   6172  C CA  . ARG B 1 307 ? 136.322 143.492 90.172  1.00 52.72  ? 307  ARG B CA  1 
ATOM   6173  C C   . ARG B 1 307 ? 137.104 142.765 91.255  1.00 52.72  ? 307  ARG B C   1 
ATOM   6174  O O   . ARG B 1 307 ? 138.310 142.986 91.415  1.00 52.72  ? 307  ARG B O   1 
ATOM   6175  C CB  . ARG B 1 307 ? 135.476 144.612 90.783  1.00 52.72  ? 307  ARG B CB  1 
ATOM   6176  C CG  . ARG B 1 307 ? 136.195 145.407 91.877  1.00 52.72  ? 307  ARG B CG  1 
ATOM   6177  C CD  . ARG B 1 307 ? 135.332 146.510 92.482  1.00 52.72  ? 307  ARG B CD  1 
ATOM   6178  N NE  . ARG B 1 307 ? 134.009 146.048 92.885  1.00 52.72  ? 307  ARG B NE  1 
ATOM   6179  C CZ  . ARG B 1 307 ? 132.901 146.762 92.739  1.00 52.72  ? 307  ARG B CZ  1 
ATOM   6180  N NH1 . ARG B 1 307 ? 132.957 147.968 92.198  1.00 52.72  ? 307  ARG B NH1 1 
ATOM   6181  N NH2 . ARG B 1 307 ? 131.737 146.272 93.129  1.00 52.72  ? 307  ARG B NH2 1 
ATOM   6182  N N   . ASN B 1 308 ? 136.429 141.880 91.998  1.00 53.58  ? 308  ASN B N   1 
ATOM   6183  C CA  . ASN B 1 308 ? 137.058 141.160 93.101  1.00 53.58  ? 308  ASN B CA  1 
ATOM   6184  C C   . ASN B 1 308 ? 138.161 140.229 92.623  1.00 53.58  ? 308  ASN B C   1 
ATOM   6185  O O   . ASN B 1 308 ? 139.230 140.178 93.243  1.00 53.58  ? 308  ASN B O   1 
ATOM   6186  C CB  . ASN B 1 308 ? 136.012 140.355 93.864  1.00 53.58  ? 308  ASN B CB  1 
ATOM   6187  C CG  . ASN B 1 308 ? 134.942 141.221 94.462  1.00 53.58  ? 308  ASN B CG  1 
ATOM   6188  O OD1 . ASN B 1 308 ? 135.231 142.238 95.084  1.00 53.58  ? 308  ASN B OD1 1 
ATOM   6189  N ND2 . ASN B 1 308 ? 133.690 140.836 94.258  1.00 53.58  ? 308  ASN B ND2 1 
ATOM   6190  N N   . LEU B 1 309 ? 137.921 139.498 91.529  1.00 51.75  ? 309  LEU B N   1 
ATOM   6191  C CA  . LEU B 1 309 ? 138.935 138.600 90.984  1.00 51.75  ? 309  LEU B CA  1 
ATOM   6192  C C   . LEU B 1 309 ? 140.136 139.364 90.449  1.00 51.75  ? 309  LEU B C   1 
ATOM   6193  O O   . LEU B 1 309 ? 141.262 138.868 90.528  1.00 51.75  ? 309  LEU B O   1 
ATOM   6194  C CB  . LEU B 1 309 ? 138.344 137.716 89.885  1.00 51.75  ? 309  LEU B CB  1 
ATOM   6195  C CG  . LEU B 1 309 ? 137.725 136.356 90.237  1.00 51.75  ? 309  LEU B CG  1 
ATOM   6196  C CD1 . LEU B 1 309 ? 136.671 136.412 91.337  1.00 51.75  ? 309  LEU B CD1 1 
ATOM   6197  C CD2 . LEU B 1 309 ? 137.156 135.708 88.982  1.00 51.75  ? 309  LEU B CD2 1 
ATOM   6198  N N   . ASN B 1 310 ? 139.923 140.569 89.925  1.00 51.27  ? 310  ASN B N   1 
ATOM   6199  C CA  . ASN B 1 310 ? 141.043 141.394 89.498  1.00 51.27  ? 310  ASN B CA  1 
ATOM   6200  C C   . ASN B 1 310 ? 141.823 141.972 90.675  1.00 51.27  ? 310  ASN B C   1 
ATOM   6201  O O   . ASN B 1 310 ? 143.043 142.129 90.572  1.00 51.27  ? 310  ASN B O   1 
ATOM   6202  C CB  . ASN B 1 310 ? 140.550 142.510 88.577  1.00 51.27  ? 310  ASN B CB  1 
ATOM   6203  C CG  . ASN B 1 310 ? 140.052 141.984 87.243  1.00 51.27  ? 310  ASN B CG  1 
ATOM   6204  O OD1 . ASN B 1 310 ? 139.234 142.615 86.574  1.00 51.27  ? 310  ASN B OD1 1 
ATOM   6205  N ND2 . ASN B 1 310 ? 140.536 140.815 86.858  1.00 51.27  ? 310  ASN B ND2 1 
ATOM   6206  N N   . ILE B 1 311 ? 141.158 142.295 91.786  1.00 55.56  ? 311  ILE B N   1 
ATOM   6207  C CA  . ILE B 1 311 ? 141.889 142.544 93.024  1.00 55.56  ? 311  ILE B CA  1 
ATOM   6208  C C   . ILE B 1 311 ? 142.540 141.258 93.515  1.00 55.56  ? 311  ILE B C   1 
ATOM   6209  O O   . ILE B 1 311 ? 143.694 141.259 93.959  1.00 55.56  ? 311  ILE B O   1 
ATOM   6210  C CB  . ILE B 1 311 ? 140.968 143.165 94.090  1.00 55.56  ? 311  ILE B CB  1 
ATOM   6211  C CG1 . ILE B 1 311 ? 140.302 144.430 93.553  1.00 55.56  ? 311  ILE B CG1 1 
ATOM   6212  C CG2 . ILE B 1 311 ? 141.746 143.503 95.346  1.00 55.56  ? 311  ILE B CG2 1 
ATOM   6213  C CD1 . ILE B 1 311 ? 141.292 145.484 93.131  1.00 55.56  ? 311  ILE B CD1 1 
ATOM   6214  N N   . LEU B 1 312 ? 141.826 140.134 93.402  1.00 53.22  ? 312  LEU B N   1 
ATOM   6215  C CA  . LEU B 1 312 ? 142.438 138.837 93.675  1.00 53.22  ? 312  LEU B CA  1 
ATOM   6216  C C   . LEU B 1 312 ? 143.515 138.482 92.655  1.00 53.22  ? 312  LEU B C   1 
ATOM   6217  O O   . LEU B 1 312 ? 144.371 137.642 92.943  1.00 53.22  ? 312  LEU B O   1 
ATOM   6218  C CB  . LEU B 1 312 ? 141.377 137.736 93.716  1.00 53.22  ? 312  LEU B CB  1 
ATOM   6219  C CG  . LEU B 1 312 ? 140.731 137.494 95.082  1.00 53.22  ? 312  LEU B CG  1 
ATOM   6220  C CD1 . LEU B 1 312 ? 139.683 136.395 95.007  1.00 53.22  ? 312  LEU B CD1 1 
ATOM   6221  C CD2 . LEU B 1 312 ? 141.788 137.160 96.117  1.00 53.22  ? 312  LEU B CD2 1 
ATOM   6222  N N   . ALA B 1 313 ? 143.480 139.078 91.462  1.00 55.47  ? 313  ALA B N   1 
ATOM   6223  C CA  . ALA B 1 313 ? 144.634 139.000 90.578  1.00 55.47  ? 313  ALA B CA  1 
ATOM   6224  C C   . ALA B 1 313 ? 145.773 139.856 91.108  1.00 55.47  ? 313  ALA B C   1 
ATOM   6225  O O   . ALA B 1 313 ? 146.812 139.338 91.530  1.00 55.47  ? 313  ALA B O   1 
ATOM   6226  C CB  . ALA B 1 313 ? 144.253 139.443 89.166  1.00 55.47  ? 313  ALA B CB  1 
ATOM   6227  N N   . PHE B 1 314 ? 145.554 141.173 91.163  1.00 54.72  ? 314  PHE B N   1 
ATOM   6228  C CA  . PHE B 1 314 ? 146.640 142.134 91.322  1.00 54.72  ? 314  PHE B CA  1 
ATOM   6229  C C   . PHE B 1 314 ? 147.283 142.088 92.701  1.00 54.72  ? 314  PHE B C   1 
ATOM   6230  O O   . PHE B 1 314 ? 148.422 142.542 92.853  1.00 54.72  ? 314  PHE B O   1 
ATOM   6231  C CB  . PHE B 1 314 ? 146.126 143.540 91.022  1.00 54.72  ? 314  PHE B CB  1 
ATOM   6232  C CG  . PHE B 1 314 ? 146.065 143.858 89.557  1.00 54.72  ? 314  PHE B CG  1 
ATOM   6233  C CD1 . PHE B 1 314 ? 147.221 143.886 88.797  1.00 54.72  ? 314  PHE B CD1 1 
ATOM   6234  C CD2 . PHE B 1 314 ? 144.853 144.119 88.936  1.00 54.72  ? 314  PHE B CD2 1 
ATOM   6235  C CE1 . PHE B 1 314 ? 147.175 144.176 87.446  1.00 54.72  ? 314  PHE B CE1 1 
ATOM   6236  C CE2 . PHE B 1 314 ? 144.795 144.405 87.584  1.00 54.72  ? 314  PHE B CE2 1 
ATOM   6237  C CZ  . PHE B 1 314 ? 145.959 144.435 86.838  1.00 54.72  ? 314  PHE B CZ  1 
ATOM   6238  N N   . MET B 1 315 ? 146.594 141.533 93.698  1.00 56.68  ? 315  MET B N   1 
ATOM   6239  C CA  . MET B 1 315 ? 147.238 141.301 94.983  1.00 56.68  ? 315  MET B CA  1 
ATOM   6240  C C   . MET B 1 315 ? 148.066 140.022 94.953  1.00 56.68  ? 315  MET B C   1 
ATOM   6241  O O   . MET B 1 315 ? 149.193 139.990 95.461  1.00 56.68  ? 315  MET B O   1 
ATOM   6242  C CB  . MET B 1 315 ? 146.193 141.240 96.098  1.00 56.68  ? 315  MET B CB  1 
ATOM   6243  C CG  . MET B 1 315 ? 146.773 141.421 97.497  1.00 56.68  ? 315  MET B CG  1 
ATOM   6244  S SD  . MET B 1 315 ? 145.564 141.268 98.827  1.00 56.68  ? 315  MET B SD  1 
ATOM   6245  C CE  . MET B 1 315 ? 144.333 142.454 98.305  1.00 56.68  ? 315  MET B CE  1 
ATOM   6246  N N   . ASN B 1 316 ? 147.530 138.962 94.347  1.00 58.34  ? 316  ASN B N   1 
ATOM   6247  C CA  . ASN B 1 316 ? 148.118 137.631 94.421  1.00 58.34  ? 316  ASN B CA  1 
ATOM   6248  C C   . ASN B 1 316 ? 149.016 137.305 93.231  1.00 58.34  ? 316  ASN B C   1 
ATOM   6249  O O   . ASN B 1 316 ? 149.371 136.141 93.028  1.00 58.34  ? 316  ASN B O   1 
ATOM   6250  C CB  . ASN B 1 316 ? 147.016 136.583 94.561  1.00 58.34  ? 316  ASN B CB  1 
ATOM   6251  C CG  . ASN B 1 316 ? 146.044 136.911 95.675  1.00 58.34  ? 316  ASN B CG  1 
ATOM   6252  O OD1 . ASN B 1 316 ? 145.331 137.913 95.623  1.00 58.34  ? 316  ASN B OD1 1 
ATOM   6253  N ND2 . ASN B 1 316 ? 146.009 136.062 96.694  1.00 58.34  ? 316  ASN B ND2 1 
ATOM   6254  N N   . ILE B 1 317 ? 149.381 138.302 92.429  1.00 58.86  ? 317  ILE B N   1 
ATOM   6255  C CA  . ILE B 1 317 ? 150.439 138.118 91.440  1.00 58.86  ? 317  ILE B CA  1 
ATOM   6256  C C   . ILE B 1 317 ? 151.794 138.567 91.966  1.00 58.86  ? 317  ILE B C   1 
ATOM   6257  O O   . ILE B 1 317 ? 152.734 138.717 91.170  1.00 58.86  ? 317  ILE B O   1 
ATOM   6258  C CB  . ILE B 1 317 ? 150.125 138.849 90.118  1.00 58.86  ? 317  ILE B CB  1 
ATOM   6259  C CG1 . ILE B 1 317 ? 149.941 140.347 90.365  1.00 58.86  ? 317  ILE B CG1 1 
ATOM   6260  C CG2 . ILE B 1 317 ? 148.954 138.199 89.392  1.00 58.86  ? 317  ILE B CG2 1 
ATOM   6261  C CD1 . ILE B 1 317 ? 149.552 141.120 89.133  1.00 58.86  ? 317  ILE B CD1 1 
ATOM   6262  N N   . LEU B 1 318 ? 151.924 138.798 93.270  1.00 61.11  ? 318  LEU B N   1 
ATOM   6263  C CA  . LEU B 1 318 ? 153.120 139.406 93.831  1.00 61.11  ? 318  LEU B CA  1 
ATOM   6264  C C   . LEU B 1 318 ? 153.642 138.652 95.050  1.00 61.11  ? 318  LEU B C   1 
ATOM   6265  O O   . LEU B 1 318 ? 154.287 139.256 95.913  1.00 61.11  ? 318  LEU B O   1 
ATOM   6266  C CB  . LEU B 1 318 ? 152.835 140.864 94.186  1.00 61.11  ? 318  LEU B CB  1 
ATOM   6267  C CG  . LEU B 1 318 ? 153.065 141.880 93.065  1.00 61.11  ? 318  LEU B CG  1 
ATOM   6268  C CD1 . LEU B 1 318 ? 152.887 143.292 93.583  1.00 61.11  ? 318  LEU B CD1 1 
ATOM   6269  C CD2 . LEU B 1 318 ? 154.421 141.716 92.410  1.00 61.11  ? 318  LEU B CD2 1 
ATOM   6270  N N   . LYS B 1 319 ? 153.362 137.350 95.155  1.00 66.74  ? 319  LYS B N   1 
ATOM   6271  C CA  . LYS B 1 319 ? 153.867 136.580 96.289  1.00 66.74  ? 319  LYS B CA  1 
ATOM   6272  C C   . LYS B 1 319 ? 155.377 136.389 96.200  1.00 66.74  ? 319  LYS B C   1 
ATOM   6273  O O   . LYS B 1 319 ? 156.116 136.738 97.128  1.00 66.74  ? 319  LYS B O   1 
ATOM   6274  C CB  . LYS B 1 319 ? 153.177 135.216 96.378  1.00 66.74  ? 319  LYS B CB  1 
ATOM   6275  C CG  . LYS B 1 319 ? 151.671 135.236 96.523  1.00 66.74  ? 319  LYS B CG  1 
ATOM   6276  C CD  . LYS B 1 319 ? 151.068 133.994 95.889  1.00 66.74  ? 319  LYS B CD  1 
ATOM   6277  C CE  . LYS B 1 319 ? 149.586 134.162 95.637  1.00 66.74  ? 319  LYS B CE  1 
ATOM   6278  N NZ  . LYS B 1 319 ? 148.829 134.413 96.896  1.00 66.74  ? 319  LYS B NZ  1 
ATOM   6279  N N   . LYS B 1 320 ? 155.854 135.834 95.086  1.00 73.41  ? 320  LYS B N   1 
ATOM   6280  C CA  . LYS B 1 320 ? 157.263 135.487 94.958  1.00 73.41  ? 320  LYS B CA  1 
ATOM   6281  C C   . LYS B 1 320 ? 158.145 136.678 94.610  1.00 73.41  ? 320  LYS B C   1 
ATOM   6282  O O   . LYS B 1 320 ? 159.372 136.565 94.707  1.00 73.41  ? 320  LYS B O   1 
ATOM   6283  C CB  . LYS B 1 320 ? 157.439 134.382 93.911  1.00 73.41  ? 320  LYS B CB  1 
ATOM   6284  C CG  . LYS B 1 320 ? 156.429 134.417 92.773  1.00 73.41  ? 320  LYS B CG  1 
ATOM   6285  C CD  . LYS B 1 320 ? 156.754 133.361 91.727  1.00 73.41  ? 320  LYS B CD  1 
ATOM   6286  C CE  . LYS B 1 320 ? 156.259 131.989 92.164  1.00 73.41  ? 320  LYS B CE  1 
ATOM   6287  N NZ  . LYS B 1 320 ? 156.421 130.960 91.100  1.00 73.41  ? 320  LYS B NZ  1 
ATOM   6288  N N   . PHE B 1 321 ? 157.561 137.809 94.216  1.00 67.15  ? 321  PHE B N   1 
ATOM   6289  C CA  . PHE B 1 321 ? 158.358 139.007 94.005  1.00 67.15  ? 321  PHE B CA  1 
ATOM   6290  C C   . PHE B 1 321 ? 158.753 139.676 95.311  1.00 67.15  ? 321  PHE B C   1 
ATOM   6291  O O   . PHE B 1 321 ? 159.769 140.376 95.350  1.00 67.15  ? 321  PHE B O   1 
ATOM   6292  C CB  . PHE B 1 321 ? 157.608 139.998 93.120  1.00 67.15  ? 321  PHE B CB  1 
ATOM   6293  C CG  . PHE B 1 321 ? 158.467 141.114 92.603  1.00 67.15  ? 321  PHE B CG  1 
ATOM   6294  C CD1 . PHE B 1 321 ? 158.241 142.421 93.006  1.00 67.15  ? 321  PHE B CD1 1 
ATOM   6295  C CD2 . PHE B 1 321 ? 159.513 140.854 91.729  1.00 67.15  ? 321  PHE B CD2 1 
ATOM   6296  C CE1 . PHE B 1 321 ? 159.033 143.453 92.537  1.00 67.15  ? 321  PHE B CE1 1 
ATOM   6297  C CE2 . PHE B 1 321 ? 160.310 141.881 91.256  1.00 67.15  ? 321  PHE B CE2 1 
ATOM   6298  C CZ  . PHE B 1 321 ? 160.069 143.182 91.662  1.00 67.15  ? 321  PHE B CZ  1 
ATOM   6299  N N   . ASP B 1 322 ? 157.992 139.466 96.385  1.00 66.91  ? 322  ASP B N   1 
ATOM   6300  C CA  . ASP B 1 322 ? 158.361 139.960 97.704  1.00 66.91  ? 322  ASP B CA  1 
ATOM   6301  C C   . ASP B 1 322 ? 159.251 138.982 98.465  1.00 66.91  ? 322  ASP B C   1 
ATOM   6302  O O   . ASP B 1 322 ? 159.373 139.087 99.690  1.00 66.91  ? 322  ASP B O   1 
ATOM   6303  C CB  . ASP B 1 322 ? 157.110 140.293 98.519  1.00 66.91  ? 322  ASP B CB  1 
ATOM   6304  C CG  . ASP B 1 322 ? 156.433 141.570 98.052  1.00 66.91  ? 322  ASP B CG  1 
ATOM   6305  O OD1 . ASP B 1 322 ? 156.722 142.640 98.627  1.00 66.91  ? 322  ASP B OD1 1 
ATOM   6306  O OD2 . ASP B 1 322 ? 155.619 141.511 97.110  1.00 66.91  ? 322  ASP B OD2 1 
ATOM   6307  N N   . LYS B 1 323 ? 159.862 138.025 97.765  1.00 64.18  ? 323  LYS B N   1 
ATOM   6308  C CA  . LYS B 1 323 ? 160.892 137.168 98.339  1.00 64.18  ? 323  LYS B CA  1 
ATOM   6309  C C   . LYS B 1 323 ? 162.201 137.273 97.568  1.00 64.18  ? 323  LYS B C   1 
ATOM   6310  O O   . LYS B 1 323 ? 163.272 137.282 98.183  1.00 64.18  ? 323  LYS B O   1 
ATOM   6311  C CB  . LYS B 1 323 ? 160.412 135.711 98.392  1.00 64.18  ? 323  LYS B CB  1 
ATOM   6312  C CG  . LYS B 1 323 ? 161.287 134.809 99.253  1.00 64.18  ? 323  LYS B CG  1 
ATOM   6313  C CD  . LYS B 1 323 ? 160.459 133.798 100.025 1.00 64.18  ? 323  LYS B CD  1 
ATOM   6314  C CE  . LYS B 1 323 ? 161.117 133.440 101.348 1.00 64.18  ? 323  LYS B CE  1 
ATOM   6315  N NZ  . LYS B 1 323 ? 160.193 132.681 102.239 1.00 64.18  ? 323  LYS B NZ  1 
ATOM   6316  N N   . VAL B 1 324 ? 162.150 137.351 96.238  1.00 63.78  ? 324  VAL B N   1 
ATOM   6317  C CA  . VAL B 1 324 ? 163.362 137.424 95.429  1.00 63.78  ? 324  VAL B CA  1 
ATOM   6318  C C   . VAL B 1 324 ? 163.881 138.860 95.431  1.00 63.78  ? 324  VAL B C   1 
ATOM   6319  O O   . VAL B 1 324 ? 165.075 139.100 95.215  1.00 63.78  ? 324  VAL B O   1 
ATOM   6320  C CB  . VAL B 1 324 ? 163.116 136.883 94.002  1.00 63.78  ? 324  VAL B CB  1 
ATOM   6321  C CG1 . VAL B 1 324 ? 162.322 137.862 93.135  1.00 63.78  ? 324  VAL B CG1 1 
ATOM   6322  C CG2 . VAL B 1 324 ? 164.429 136.487 93.331  1.00 63.78  ? 324  VAL B CG2 1 
ATOM   6323  N N   . THR B 1 325 ? 162.999 139.824 95.699  1.00 64.36  ? 325  THR B N   1 
ATOM   6324  C CA  . THR B 1 325 ? 163.430 141.206 95.865  1.00 64.36  ? 325  THR B CA  1 
ATOM   6325  C C   . THR B 1 325 ? 163.117 141.737 97.261  1.00 64.36  ? 325  THR B C   1 
ATOM   6326  O O   . THR B 1 325 ? 163.962 142.405 97.868  1.00 64.36  ? 325  THR B O   1 
ATOM   6327  C CB  . THR B 1 325 ? 162.792 142.097 94.794  1.00 64.36  ? 325  THR B CB  1 
ATOM   6328  O OG1 . THR B 1 325 ? 161.419 141.736 94.616  1.00 64.36  ? 325  THR B OG1 1 
ATOM   6329  C CG2 . THR B 1 325 ? 163.524 141.938 93.470  1.00 64.36  ? 325  THR B CG2 1 
ATOM   6330  N N   . GLY B 1 326 ? 161.926 141.446 97.785  1.00 62.05  ? 326  GLY B N   1 
ATOM   6331  C CA  . GLY B 1 326 ? 161.608 141.723 99.175  1.00 62.05  ? 326  GLY B CA  1 
ATOM   6332  C C   . GLY B 1 326 ? 161.457 143.181 99.561  1.00 62.05  ? 326  GLY B C   1 
ATOM   6333  O O   . GLY B 1 326 ? 162.282 143.711 100.311 1.00 62.05  ? 326  GLY B O   1 
ATOM   6334  N N   . LYS B 1 327 ? 160.411 143.844 99.067  1.00 68.23  ? 327  LYS B N   1 
ATOM   6335  C CA  . LYS B 1 327 ? 160.208 145.254 99.379  1.00 68.23  ? 327  LYS B CA  1 
ATOM   6336  C C   . LYS B 1 327 ? 158.820 145.520 99.948  1.00 68.23  ? 327  LYS B C   1 
ATOM   6337  O O   . LYS B 1 327 ? 158.080 144.588 100.276 1.00 68.23  ? 327  LYS B O   1 
ATOM   6338  C CB  . LYS B 1 327 ? 160.427 146.113 98.133  1.00 68.23  ? 327  LYS B CB  1 
ATOM   6339  C CG  . LYS B 1 327 ? 161.855 146.120 97.627  1.00 68.23  ? 327  LYS B CG  1 
ATOM   6340  C CD  . LYS B 1 327 ? 161.983 146.977 96.387  1.00 68.23  ? 327  LYS B CD  1 
ATOM   6341  C CE  . LYS B 1 327 ? 163.419 147.043 95.910  1.00 68.23  ? 327  LYS B CE  1 
ATOM   6342  N NZ  . LYS B 1 327 ? 163.900 145.711 95.452  1.00 68.23  ? 327  LYS B NZ  1 
ATOM   6343  N N   . GLN B 1 328 ? 158.467 146.800 100.076 1.00 65.65  ? 328  GLN B N   1 
ATOM   6344  C CA  . GLN B 1 328 ? 157.148 147.223 100.528 1.00 65.65  ? 328  GLN B CA  1 
ATOM   6345  C C   . GLN B 1 328 ? 156.233 147.593 99.369  1.00 65.65  ? 328  GLN B C   1 
ATOM   6346  O O   . GLN B 1 328 ? 155.403 148.501 99.500  1.00 65.65  ? 328  GLN B O   1 
ATOM   6347  C CB  . GLN B 1 328 ? 157.280 148.399 101.497 1.00 65.65  ? 328  GLN B CB  1 
ATOM   6348  C CG  . GLN B 1 328 ? 157.955 148.057 102.816 1.00 65.65  ? 328  GLN B CG  1 
ATOM   6349  C CD  . GLN B 1 328 ? 156.961 147.789 103.930 1.00 65.65  ? 328  GLN B CD  1 
ATOM   6350  O OE1 . GLN B 1 328 ? 156.139 146.876 103.840 1.00 65.65  ? 328  GLN B OE1 1 
ATOM   6351  N NE2 . GLN B 1 328 ? 157.028 148.590 104.989 1.00 65.65  ? 328  GLN B NE2 1 
ATOM   6352  N N   . ILE B 1 329 ? 156.368 146.909 98.229  1.00 64.69  ? 329  ILE B N   1 
ATOM   6353  C CA  . ILE B 1 329 ? 155.669 147.311 97.011  1.00 64.69  ? 329  ILE B CA  1 
ATOM   6354  C C   . ILE B 1 329 ? 154.230 146.821 96.967  1.00 64.69  ? 329  ILE B C   1 
ATOM   6355  O O   . ILE B 1 329 ? 153.425 147.375 96.208  1.00 64.69  ? 329  ILE B O   1 
ATOM   6356  C CB  . ILE B 1 329 ? 156.488 146.828 95.794  1.00 64.69  ? 329  ILE B CB  1 
ATOM   6357  C CG1 . ILE B 1 329 ? 156.187 147.665 94.545  1.00 64.69  ? 329  ILE B CG1 1 
ATOM   6358  C CG2 . ILE B 1 329 ? 156.266 145.342 95.520  1.00 64.69  ? 329  ILE B CG2 1 
ATOM   6359  C CD1 . ILE B 1 329 ? 156.457 149.136 94.720  1.00 64.69  ? 329  ILE B CD1 1 
ATOM   6360  N N   . LEU B 1 330 ? 153.872 145.821 97.776  1.00 61.42  ? 330  LEU B N   1 
ATOM   6361  C CA  . LEU B 1 330 ? 152.519 145.269 97.709  1.00 61.42  ? 330  LEU B CA  1 
ATOM   6362  C C   . LEU B 1 330 ? 151.405 146.207 98.187  1.00 61.42  ? 330  LEU B C   1 
ATOM   6363  O O   . LEU B 1 330 ? 150.267 146.026 97.715  1.00 61.42  ? 330  LEU B O   1 
ATOM   6364  C CB  . LEU B 1 330 ? 152.466 143.909 98.430  1.00 61.42  ? 330  LEU B CB  1 
ATOM   6365  C CG  . LEU B 1 330 ? 152.774 143.617 99.900  1.00 61.42  ? 330  LEU B CG  1 
ATOM   6366  C CD1 . LEU B 1 330 ? 151.492 143.611 100.716 1.00 61.42  ? 330  LEU B CD1 1 
ATOM   6367  C CD2 . LEU B 1 330 ? 153.513 142.299 100.045 1.00 61.42  ? 330  LEU B CD2 1 
ATOM   6368  N N   . PRO B 1 331 ? 151.609 147.187 99.079  1.00 61.42  ? 331  PRO B N   1 
ATOM   6369  C CA  . PRO B 1 331 ? 150.634 148.282 99.156  1.00 61.42  ? 331  PRO B CA  1 
ATOM   6370  C C   . PRO B 1 331 ? 150.949 149.488 98.283  1.00 61.42  ? 331  PRO B C   1 
ATOM   6371  O O   . PRO B 1 331 ? 150.035 150.282 98.025  1.00 61.42  ? 331  PRO B O   1 
ATOM   6372  C CB  . PRO B 1 331 ? 150.673 148.669 100.640 1.00 61.42  ? 331  PRO B CB  1 
ATOM   6373  C CG  . PRO B 1 331 ? 152.056 148.446 101.011 1.00 61.42  ? 331  PRO B CG  1 
ATOM   6374  C CD  . PRO B 1 331 ? 152.447 147.187 100.301 1.00 61.42  ? 331  PRO B CD  1 
ATOM   6375  N N   . ILE B 1 332 ? 152.193 149.657 97.828  1.00 60.07  ? 332  ILE B N   1 
ATOM   6376  C CA  . ILE B 1 332 ? 152.536 150.826 97.021  1.00 60.07  ? 332  ILE B CA  1 
ATOM   6377  C C   . ILE B 1 332 ? 151.970 150.681 95.616  1.00 60.07  ? 332  ILE B C   1 
ATOM   6378  O O   . ILE B 1 332 ? 151.315 151.592 95.094  1.00 60.07  ? 332  ILE B O   1 
ATOM   6379  C CB  . ILE B 1 332 ? 154.061 151.040 97.002  1.00 60.07  ? 332  ILE B CB  1 
ATOM   6380  C CG1 . ILE B 1 332 ? 154.550 151.504 98.374  1.00 60.07  ? 332  ILE B CG1 1 
ATOM   6381  C CG2 . ILE B 1 332 ? 154.458 152.061 95.941  1.00 60.07  ? 332  ILE B CG2 1 
ATOM   6382  C CD1 . ILE B 1 332 ? 153.862 152.753 98.882  1.00 60.07  ? 332  ILE B CD1 1 
ATOM   6383  N N   . TYR B 1 333 ? 152.213 149.528 94.987  1.00 59.40  ? 333  TYR B N   1 
ATOM   6384  C CA  . TYR B 1 333 ? 151.581 149.193 93.717  1.00 59.40  ? 333  TYR B CA  1 
ATOM   6385  C C   . TYR B 1 333 ? 150.063 149.127 93.836  1.00 59.40  ? 333  TYR B C   1 
ATOM   6386  O O   . TYR B 1 333 ? 149.368 149.475 92.881  1.00 59.40  ? 333  TYR B O   1 
ATOM   6387  C CB  . TYR B 1 333 ? 152.119 147.850 93.214  1.00 59.40  ? 333  TYR B CB  1 
ATOM   6388  C CG  . TYR B 1 333 ? 151.496 147.317 91.937  1.00 59.40  ? 333  TYR B CG  1 
ATOM   6389  C CD1 . TYR B 1 333 ? 151.269 148.140 90.836  1.00 59.40  ? 333  TYR B CD1 1 
ATOM   6390  C CD2 . TYR B 1 333 ? 151.109 145.985 91.850  1.00 59.40  ? 333  TYR B CD2 1 
ATOM   6391  C CE1 . TYR B 1 333 ? 150.685 147.646 89.686  1.00 59.40  ? 333  TYR B CE1 1 
ATOM   6392  C CE2 . TYR B 1 333 ? 150.531 145.482 90.703  1.00 59.40  ? 333  TYR B CE2 1 
ATOM   6393  C CZ  . TYR B 1 333 ? 150.322 146.315 89.627  1.00 59.40  ? 333  TYR B CZ  1 
ATOM   6394  O OH  . TYR B 1 333 ? 149.746 145.810 88.489  1.00 59.40  ? 333  TYR B OH  1 
ATOM   6395  N N   . LEU B 1 334 ? 149.535 148.728 94.994  1.00 54.79  ? 334  LEU B N   1 
ATOM   6396  C CA  . LEU B 1 334 ? 148.097 148.529 95.126  1.00 54.79  ? 334  LEU B CA  1 
ATOM   6397  C C   . LEU B 1 334 ? 147.323 149.843 95.088  1.00 54.79  ? 334  LEU B C   1 
ATOM   6398  O O   . LEU B 1 334 ? 146.138 149.841 94.741  1.00 54.79  ? 334  LEU B O   1 
ATOM   6399  C CB  . LEU B 1 334 ? 147.808 147.764 96.421  1.00 54.79  ? 334  LEU B CB  1 
ATOM   6400  C CG  . LEU B 1 334 ? 146.424 147.166 96.674  1.00 54.79  ? 334  LEU B CG  1 
ATOM   6401  C CD1 . LEU B 1 334 ? 145.938 146.465 95.426  1.00 54.79  ? 334  LEU B CD1 1 
ATOM   6402  C CD2 . LEU B 1 334 ? 146.458 146.195 97.840  1.00 54.79  ? 334  LEU B CD2 1 
ATOM   6403  N N   . LYS B 1 335 ? 147.972 150.968 95.386  1.00 50.63  ? 335  LYS B N   1 
ATOM   6404  C CA  . LYS B 1 335 ? 147.278 152.249 95.402  1.00 50.63  ? 335  LYS B CA  1 
ATOM   6405  C C   . LYS B 1 335 ? 147.247 152.951 94.049  1.00 50.63  ? 335  LYS B C   1 
ATOM   6406  O O   . LYS B 1 335 ? 146.752 154.079 93.978  1.00 50.63  ? 335  LYS B O   1 
ATOM   6407  C CB  . LYS B 1 335 ? 147.890 153.170 96.459  1.00 50.63  ? 335  LYS B CB  1 
ATOM   6408  C CG  . LYS B 1 335 ? 147.778 152.669 97.908  1.00 50.63  ? 335  LYS B CG  1 
ATOM   6409  C CD  . LYS B 1 335 ? 146.348 152.702 98.472  1.00 50.63  ? 335  LYS B CD  1 
ATOM   6410  C CE  . LYS B 1 335 ? 145.698 151.315 98.532  1.00 50.63  ? 335  LYS B CE  1 
ATOM   6411  N NZ  . LYS B 1 335 ? 144.348 151.339 99.152  1.00 50.63  ? 335  LYS B NZ  1 
ATOM   6412  N N   . VAL B 1 336 ? 147.774 152.345 92.982  1.00 57.58  ? 336  VAL B N   1 
ATOM   6413  C CA  . VAL B 1 336 ? 147.327 152.703 91.641  1.00 57.58  ? 336  VAL B CA  1 
ATOM   6414  C C   . VAL B 1 336 ? 146.363 151.673 91.090  1.00 57.58  ? 336  VAL B C   1 
ATOM   6415  O O   . VAL B 1 336 ? 145.758 151.896 90.034  1.00 57.58  ? 336  VAL B O   1 
ATOM   6416  C CB  . VAL B 1 336 ? 148.499 152.927 90.660  1.00 57.58  ? 336  VAL B CB  1 
ATOM   6417  C CG1 . VAL B 1 336 ? 149.293 154.152 91.059  1.00 57.58  ? 336  VAL B CG1 1 
ATOM   6418  C CG2 . VAL B 1 336 ? 149.386 151.715 90.554  1.00 57.58  ? 336  VAL B CG2 1 
ATOM   6419  N N   . VAL B 1 337 ? 146.184 150.559 91.793  1.00 55.24  ? 337  VAL B N   1 
ATOM   6420  C CA  . VAL B 1 337 ? 145.152 149.581 91.486  1.00 55.24  ? 337  VAL B CA  1 
ATOM   6421  C C   . VAL B 1 337 ? 143.831 149.947 92.142  1.00 55.24  ? 337  VAL B C   1 
ATOM   6422  O O   . VAL B 1 337 ? 142.789 149.964 91.489  1.00 55.24  ? 337  VAL B O   1 
ATOM   6423  C CB  . VAL B 1 337 ? 145.609 148.165 91.901  1.00 55.24  ? 337  VAL B CB  1 
ATOM   6424  C CG1 . VAL B 1 337 ? 144.618 147.126 91.408  1.00 55.24  ? 337  VAL B CG1 1 
ATOM   6425  C CG2 . VAL B 1 337 ? 146.979 147.874 91.335  1.00 55.24  ? 337  VAL B CG2 1 
ATOM   6426  N N   . GLU B 1 338 ? 143.855 150.243 93.441  1.00 48.76  ? 338  GLU B N   1 
ATOM   6427  C CA  . GLU B 1 338 ? 142.620 150.588 94.129  1.00 48.76  ? 338  GLU B CA  1 
ATOM   6428  C C   . GLU B 1 338 ? 142.142 151.989 93.772  1.00 48.76  ? 338  GLU B C   1 
ATOM   6429  O O   . GLU B 1 338 ? 140.934 152.244 93.806  1.00 48.76  ? 338  GLU B O   1 
ATOM   6430  C CB  . GLU B 1 338 ? 142.813 150.476 95.639  1.00 48.76  ? 338  GLU B CB  1 
ATOM   6431  C CG  . GLU B 1 338 ? 143.280 149.113 96.141  1.00 48.76  ? 338  GLU B CG  1 
ATOM   6432  C CD  . GLU B 1 338 ? 142.274 148.006 95.947  1.00 48.76  ? 338  GLU B CD  1 
ATOM   6433  O OE1 . GLU B 1 338 ? 141.067 148.291 95.925  1.00 48.76  ? 338  GLU B OE1 1 
ATOM   6434  O OE2 . GLU B 1 338 ? 142.687 146.836 95.854  1.00 48.76  ? 338  GLU B OE2 1 
ATOM   6435  N N   . SER B 1 339 ? 143.058 152.897 93.424  1.00 55.05  ? 339  SER B N   1 
ATOM   6436  C CA  . SER B 1 339 ? 142.689 154.224 92.948  1.00 55.05  ? 339  SER B CA  1 
ATOM   6437  C C   . SER B 1 339 ? 142.354 154.256 91.468  1.00 55.05  ? 339  SER B C   1 
ATOM   6438  O O   . SER B 1 339 ? 141.969 155.314 90.960  1.00 55.05  ? 339  SER B O   1 
ATOM   6439  C CB  . SER B 1 339 ? 143.806 155.235 93.201  1.00 55.05  ? 339  SER B CB  1 
ATOM   6440  O OG  . SER B 1 339 ? 145.019 154.793 92.632  1.00 55.05  ? 339  SER B OG  1 
ATOM   6441  N N   . SER B 1 340 ? 142.518 153.147 90.756  1.00 56.32  ? 340  SER B N   1 
ATOM   6442  C CA  . SER B 1 340 ? 142.035 153.115 89.392  1.00 56.32  ? 340  SER B CA  1 
ATOM   6443  C C   . SER B 1 340 ? 140.516 153.024 89.394  1.00 56.32  ? 340  SER B C   1 
ATOM   6444  O O   . SER B 1 340 ? 139.894 152.718 90.414  1.00 56.32  ? 340  SER B O   1 
ATOM   6445  C CB  . SER B 1 340 ? 142.642 151.951 88.627  1.00 56.32  ? 340  SER B CB  1 
ATOM   6446  O OG  . SER B 1 340 ? 142.577 152.213 87.240  1.00 56.32  ? 340  SER B OG  1 
ATOM   6447  N N   . TYR B 1 341 ? 139.932 153.254 88.213  1.00 54.09  ? 341  TYR B N   1 
ATOM   6448  C CA  . TYR B 1 341 ? 138.509 153.573 88.102  1.00 54.09  ? 341  TYR B CA  1 
ATOM   6449  C C   . TYR B 1 341 ? 137.617 152.419 88.549  1.00 54.09  ? 341  TYR B C   1 
ATOM   6450  O O   . TYR B 1 341 ? 136.482 152.639 88.989  1.00 54.09  ? 341  TYR B O   1 
ATOM   6451  C CB  . TYR B 1 341 ? 138.186 153.983 86.661  1.00 54.09  ? 341  TYR B CB  1 
ATOM   6452  C CG  . TYR B 1 341 ? 136.730 154.298 86.424  1.00 54.09  ? 341  TYR B CG  1 
ATOM   6453  C CD1 . TYR B 1 341 ? 135.872 153.349 85.881  1.00 54.09  ? 341  TYR B CD1 1 
ATOM   6454  C CD2 . TYR B 1 341 ? 136.209 155.537 86.757  1.00 54.09  ? 341  TYR B CD2 1 
ATOM   6455  C CE1 . TYR B 1 341 ? 134.540 153.621 85.685  1.00 54.09  ? 341  TYR B CE1 1 
ATOM   6456  C CE2 . TYR B 1 341 ? 134.873 155.825 86.553  1.00 54.09  ? 341  TYR B CE2 1 
ATOM   6457  C CZ  . TYR B 1 341 ? 134.046 154.861 86.012  1.00 54.09  ? 341  TYR B CZ  1 
ATOM   6458  O OH  . TYR B 1 341 ? 132.716 155.140 85.806  1.00 54.09  ? 341  TYR B OH  1 
ATOM   6459  N N   . PHE B 1 342 ? 138.116 151.185 88.474  1.00 56.33  ? 342  PHE B N   1 
ATOM   6460  C CA  . PHE B 1 342 ? 137.266 150.050 88.804  1.00 56.33  ? 342  PHE B CA  1 
ATOM   6461  C C   . PHE B 1 342 ? 137.110 149.842 90.305  1.00 56.33  ? 342  PHE B C   1 
ATOM   6462  O O   . PHE B 1 342 ? 136.183 149.140 90.719  1.00 56.33  ? 342  PHE B O   1 
ATOM   6463  C CB  . PHE B 1 342 ? 137.767 148.770 88.114  1.00 56.33  ? 342  PHE B CB  1 
ATOM   6464  C CG  . PHE B 1 342 ? 139.086 148.261 88.604  1.00 56.33  ? 342  PHE B CG  1 
ATOM   6465  C CD1 . PHE B 1 342 ? 140.276 148.801 88.146  1.00 56.33  ? 342  PHE B CD1 1 
ATOM   6466  C CD2 . PHE B 1 342 ? 139.134 147.193 89.480  1.00 56.33  ? 342  PHE B CD2 1 
ATOM   6467  C CE1 . PHE B 1 342 ? 141.488 148.312 88.587  1.00 56.33  ? 342  PHE B CE1 1 
ATOM   6468  C CE2 . PHE B 1 342 ? 140.338 146.702 89.918  1.00 56.33  ? 342  PHE B CE2 1 
ATOM   6469  C CZ  . PHE B 1 342 ? 141.520 147.260 89.476  1.00 56.33  ? 342  PHE B CZ  1 
ATOM   6470  N N   . ASN B 1 343 ? 137.968 150.445 91.132  1.00 47.77  ? 343  ASN B N   1 
ATOM   6471  C CA  . ASN B 1 343 ? 137.741 150.436 92.568  1.00 47.77  ? 343  ASN B CA  1 
ATOM   6472  C C   . ASN B 1 343 ? 137.621 151.812 93.206  1.00 47.77  ? 343  ASN B C   1 
ATOM   6473  O O   . ASN B 1 343 ? 137.021 151.912 94.278  1.00 47.77  ? 343  ASN B O   1 
ATOM   6474  C CB  . ASN B 1 343 ? 138.849 149.677 93.304  1.00 47.77  ? 343  ASN B CB  1 
ATOM   6475  C CG  . ASN B 1 343 ? 138.353 149.071 94.588  1.00 47.77  ? 343  ASN B CG  1 
ATOM   6476  O OD1 . ASN B 1 343 ? 137.320 148.405 94.616  1.00 47.77  ? 343  ASN B OD1 1 
ATOM   6477  N ND2 . ASN B 1 343 ? 139.041 149.362 95.674  1.00 47.77  ? 343  ASN B ND2 1 
ATOM   6478  N N   . ILE B 1 344 ? 138.156 152.871 92.588  1.00 48.71  ? 344  ILE B N   1 
ATOM   6479  C CA  . ILE B 1 344 ? 138.021 154.198 93.181  1.00 48.71  ? 344  ILE B CA  1 
ATOM   6480  C C   . ILE B 1 344 ? 136.592 154.704 92.995  1.00 48.71  ? 344  ILE B C   1 
ATOM   6481  O O   . ILE B 1 344 ? 136.162 155.652 93.662  1.00 48.71  ? 344  ILE B O   1 
ATOM   6482  C CB  . ILE B 1 344 ? 139.068 155.160 92.586  1.00 48.71  ? 344  ILE B CB  1 
ATOM   6483  C CG1 . ILE B 1 344 ? 139.255 156.394 93.469  1.00 48.71  ? 344  ILE B CG1 1 
ATOM   6484  C CG2 . ILE B 1 344 ? 138.634 155.650 91.225  1.00 48.71  ? 344  ILE B CG2 1 
ATOM   6485  C CD1 . ILE B 1 344 ? 140.367 157.318 93.019  1.00 48.71  ? 344  ILE B CD1 1 
ATOM   6486  N N   . SER B 1 345 ? 135.825 154.076 92.113  1.00 47.46  ? 345  SER B N   1 
ATOM   6487  C CA  . SER B 1 345 ? 134.390 154.271 92.062  1.00 47.46  ? 345  SER B CA  1 
ATOM   6488  C C   . SER B 1 345 ? 133.678 153.061 92.641  1.00 47.46  ? 345  SER B C   1 
ATOM   6489  O O   . SER B 1 345 ? 134.284 152.015 92.880  1.00 47.46  ? 345  SER B O   1 
ATOM   6490  C CB  . SER B 1 345 ? 133.912 154.495 90.633  1.00 47.46  ? 345  SER B CB  1 
ATOM   6491  O OG  . SER B 1 345 ? 132.499 154.539 90.602  1.00 47.46  ? 345  SER B OG  1 
ATOM   6492  N N   . ASP B 1 346 ? 132.383 153.234 92.885  1.00 47.30  ? 346  ASP B N   1 
ATOM   6493  C CA  . ASP B 1 346 ? 131.412 152.168 93.106  1.00 47.30  ? 346  ASP B CA  1 
ATOM   6494  C C   . ASP B 1 346 ? 130.150 152.459 92.313  1.00 47.30  ? 346  ASP B C   1 
ATOM   6495  O O   . ASP B 1 346 ? 129.033 152.331 92.818  1.00 47.30  ? 346  ASP B O   1 
ATOM   6496  C CB  . ASP B 1 346 ? 131.080 151.983 94.589  1.00 47.30  ? 346  ASP B CB  1 
ATOM   6497  C CG  . ASP B 1 346 ? 132.135 151.182 95.351  1.00 47.30  ? 346  ASP B CG  1 
ATOM   6498  O OD1 . ASP B 1 346 ? 132.786 150.310 94.746  1.00 47.30  ? 346  ASP B OD1 1 
ATOM   6499  O OD2 . ASP B 1 346 ? 132.298 151.406 96.568  1.00 47.30  ? 346  ASP B OD2 1 
ATOM   6500  N N   . LYS B 1 347 ? 130.312 152.872 91.053  1.00 53.88  ? 347  LYS B N   1 
ATOM   6501  C CA  . LYS B 1 347 ? 129.155 153.199 90.226  1.00 53.88  ? 347  LYS B CA  1 
ATOM   6502  C C   . LYS B 1 347 ? 128.379 151.959 89.801  1.00 53.88  ? 347  LYS B C   1 
ATOM   6503  O O   . LYS B 1 347 ? 127.243 152.079 89.337  1.00 53.88  ? 347  LYS B O   1 
ATOM   6504  C CB  . LYS B 1 347 ? 129.576 153.994 88.991  1.00 53.88  ? 347  LYS B CB  1 
ATOM   6505  C CG  . LYS B 1 347 ? 129.686 155.494 89.208  1.00 53.88  ? 347  LYS B CG  1 
ATOM   6506  C CD  . LYS B 1 347 ? 129.388 156.285 87.939  1.00 53.88  ? 347  LYS B CD  1 
ATOM   6507  C CE  . LYS B 1 347 ? 128.061 155.885 87.314  1.00 53.88  ? 347  LYS B CE  1 
ATOM   6508  N NZ  . LYS B 1 347 ? 127.528 156.958 86.428  1.00 53.88  ? 347  LYS B NZ  1 
ATOM   6509  N N   . VAL B 1 348 ? 128.977 150.770 89.894  1.00 58.78  ? 348  VAL B N   1 
ATOM   6510  C CA  . VAL B 1 348 ? 128.182 149.560 89.725  1.00 58.78  ? 348  VAL B CA  1 
ATOM   6511  C C   . VAL B 1 348 ? 127.389 149.255 90.990  1.00 58.78  ? 348  VAL B C   1 
ATOM   6512  O O   . VAL B 1 348 ? 126.355 148.582 90.921  1.00 58.78  ? 348  VAL B O   1 
ATOM   6513  C CB  . VAL B 1 348 ? 129.070 148.370 89.302  1.00 58.78  ? 348  VAL B CB  1 
ATOM   6514  C CG1 . VAL B 1 348 ? 129.849 148.722 88.052  1.00 58.78  ? 348  VAL B CG1 1 
ATOM   6515  C CG2 . VAL B 1 348 ? 130.026 147.960 90.411  1.00 58.78  ? 348  VAL B CG2 1 
ATOM   6516  N N   . MET B 1 349 ? 127.826 149.770 92.142  1.00 59.48  ? 349  MET B N   1 
ATOM   6517  C CA  . MET B 1 349 ? 127.193 149.471 93.418  1.00 59.48  ? 349  MET B CA  1 
ATOM   6518  C C   . MET B 1 349 ? 126.022 150.387 93.735  1.00 59.48  ? 349  MET B C   1 
ATOM   6519  O O   . MET B 1 349 ? 125.183 150.026 94.565  1.00 59.48  ? 349  MET B O   1 
ATOM   6520  C CB  . MET B 1 349 ? 128.223 149.547 94.549  1.00 59.48  ? 349  MET B CB  1 
ATOM   6521  C CG  . MET B 1 349 ? 129.082 148.303 94.680  1.00 59.48  ? 349  MET B CG  1 
ATOM   6522  S SD  . MET B 1 349 ? 128.224 146.986 95.562  1.00 59.48  ? 349  MET B SD  1 
ATOM   6523  C CE  . MET B 1 349 ? 129.564 145.840 95.867  1.00 59.48  ? 349  MET B CE  1 
ATOM   6524  N N   . ILE B 1 350 ? 125.942 151.562 93.108  1.00 58.26  ? 350  ILE B N   1 
ATOM   6525  C CA  . ILE B 1 350 ? 124.732 152.370 93.227  1.00 58.26  ? 350  ILE B CA  1 
ATOM   6526  C C   . ILE B 1 350 ? 123.609 151.723 92.420  1.00 58.26  ? 350  ILE B C   1 
ATOM   6527  O O   . ILE B 1 350 ? 122.422 151.852 92.745  1.00 58.26  ? 350  ILE B O   1 
ATOM   6528  C CB  . ILE B 1 350 ? 125.016 153.830 92.808  1.00 58.26  ? 350  ILE B CB  1 
ATOM   6529  C CG1 . ILE B 1 350 ? 123.790 154.733 92.972  1.00 58.26  ? 350  ILE B CG1 1 
ATOM   6530  C CG2 . ILE B 1 350 ? 125.536 153.917 91.393  1.00 58.26  ? 350  ILE B CG2 1 
ATOM   6531  C CD1 . ILE B 1 350 ? 124.071 156.196 92.704  1.00 58.26  ? 350  ILE B CD1 1 
ATOM   6532  N N   . LEU B 1 351 ? 123.976 150.945 91.401  1.00 57.89  ? 351  LEU B N   1 
ATOM   6533  C CA  . LEU B 1 351 ? 123.025 150.109 90.686  1.00 57.89  ? 351  LEU B CA  1 
ATOM   6534  C C   . LEU B 1 351 ? 122.624 148.865 91.466  1.00 57.89  ? 351  LEU B C   1 
ATOM   6535  O O   . LEU B 1 351 ? 121.621 148.239 91.116  1.00 57.89  ? 351  LEU B O   1 
ATOM   6536  C CB  . LEU B 1 351 ? 123.600 149.700 89.332  1.00 57.89  ? 351  LEU B CB  1 
ATOM   6537  C CG  . LEU B 1 351 ? 124.328 150.809 88.580  1.00 57.89  ? 351  LEU B CG  1 
ATOM   6538  C CD1 . LEU B 1 351 ? 125.139 150.243 87.432  1.00 57.89  ? 351  LEU B CD1 1 
ATOM   6539  C CD2 . LEU B 1 351 ? 123.344 151.845 88.081  1.00 57.89  ? 351  LEU B CD2 1 
ATOM   6540  N N   . SER B 1 352 ? 123.369 148.503 92.515  1.00 63.51  ? 352  SER B N   1 
ATOM   6541  C CA  . SER B 1 352 ? 123.065 147.285 93.261  1.00 63.51  ? 352  SER B CA  1 
ATOM   6542  C C   . SER B 1 352 ? 121.804 147.444 94.099  1.00 63.51  ? 352  SER B C   1 
ATOM   6543  O O   . SER B 1 352 ? 121.135 146.453 94.415  1.00 63.51  ? 352  SER B O   1 
ATOM   6544  C CB  . SER B 1 352 ? 124.248 146.901 94.146  1.00 63.51  ? 352  SER B CB  1 
ATOM   6545  O OG  . SER B 1 352 ? 124.334 147.755 95.272  1.00 63.51  ? 352  SER B OG  1 
ATOM   6546  N N   . ASP B 1 353 ? 121.468 148.672 94.479  1.00 58.26  ? 353  ASP B N   1 
ATOM   6547  C CA  . ASP B 1 353 ? 120.189 148.951 95.115  1.00 58.26  ? 353  ASP B CA  1 
ATOM   6548  C C   . ASP B 1 353 ? 119.186 149.566 94.150  1.00 58.26  ? 353  ASP B C   1 
ATOM   6549  O O   . ASP B 1 353 ? 117.984 149.564 94.438  1.00 58.26  ? 353  ASP B O   1 
ATOM   6550  C CB  . ASP B 1 353 ? 120.384 149.872 96.322  1.00 58.26  ? 353  ASP B CB  1 
ATOM   6551  C CG  . ASP B 1 353 ? 119.265 149.744 97.337  1.00 58.26  ? 353  ASP B CG  1 
ATOM   6552  O OD1 . ASP B 1 353 ? 119.060 150.691 98.126  1.00 58.26  ? 353  ASP B OD1 1 
ATOM   6553  O OD2 . ASP B 1 353 ? 118.586 148.695 97.341  1.00 58.26  ? 353  ASP B OD2 1 
ATOM   6554  N N   . GLU B 1 354 ? 119.653 150.084 93.013  1.00 60.01  ? 354  GLU B N   1 
ATOM   6555  C CA  . GLU B 1 354 ? 118.770 150.591 91.973  1.00 60.01  ? 354  GLU B CA  1 
ATOM   6556  C C   . GLU B 1 354 ? 117.969 149.479 91.304  1.00 60.01  ? 354  GLU B C   1 
ATOM   6557  O O   . GLU B 1 354 ? 116.827 149.713 90.900  1.00 60.01  ? 354  GLU B O   1 
ATOM   6558  C CB  . GLU B 1 354 ? 119.606 151.369 90.947  1.00 60.01  ? 354  GLU B CB  1 
ATOM   6559  C CG  . GLU B 1 354 ? 118.912 151.818 89.667  1.00 60.01  ? 354  GLU B CG  1 
ATOM   6560  C CD  . GLU B 1 354 ? 119.107 150.844 88.518  1.00 60.01  ? 354  GLU B CD  1 
ATOM   6561  O OE1 . GLU B 1 354 ? 120.269 150.537 88.185  1.00 60.01  ? 354  GLU B OE1 1 
ATOM   6562  O OE2 . GLU B 1 354 ? 118.094 150.378 87.958  1.00 60.01  ? 354  GLU B OE2 1 
ATOM   6563  N N   . VAL B 1 355 ? 118.523 148.269 91.215  1.00 61.72  ? 355  VAL B N   1 
ATOM   6564  C CA  . VAL B 1 355 ? 117.811 147.165 90.577  1.00 61.72  ? 355  VAL B CA  1 
ATOM   6565  C C   . VAL B 1 355 ? 116.590 146.704 91.363  1.00 61.72  ? 355  VAL B C   1 
ATOM   6566  O O   . VAL B 1 355 ? 115.687 146.091 90.782  1.00 61.72  ? 355  VAL B O   1 
ATOM   6567  C CB  . VAL B 1 355 ? 118.760 145.981 90.347  1.00 61.72  ? 355  VAL B CB  1 
ATOM   6568  C CG1 . VAL B 1 355 ? 119.753 146.313 89.250  1.00 61.72  ? 355  VAL B CG1 1 
ATOM   6569  C CG2 . VAL B 1 355 ? 119.491 145.649 91.635  1.00 61.72  ? 355  VAL B CG2 1 
ATOM   6570  N N   . GLU B 1 356 ? 116.525 146.988 92.659  1.00 61.18  ? 356  GLU B N   1 
ATOM   6571  C CA  . GLU B 1 356 ? 115.379 146.619 93.474  1.00 61.18  ? 356  GLU B CA  1 
ATOM   6572  C C   . GLU B 1 356 ? 114.534 147.814 93.884  1.00 61.18  ? 356  GLU B C   1 
ATOM   6573  O O   . GLU B 1 356 ? 114.068 147.852 95.025  1.00 61.18  ? 356  GLU B O   1 
ATOM   6574  C CB  . GLU B 1 356 ? 115.834 145.874 94.729  1.00 61.18  ? 356  GLU B CB  1 
ATOM   6575  C CG  . GLU B 1 356 ? 116.432 144.508 94.478  1.00 61.18  ? 356  GLU B CG  1 
ATOM   6576  C CD  . GLU B 1 356 ? 116.887 143.836 95.760  1.00 61.18  ? 356  GLU B CD  1 
ATOM   6577  O OE1 . GLU B 1 356 ? 116.849 144.488 96.822  1.00 61.18  ? 356  GLU B OE1 1 
ATOM   6578  O OE2 . GLU B 1 356 ? 117.284 142.655 95.707  1.00 61.18  ? 356  GLU B OE2 1 
ATOM   6579  N N   . GLU B 1 357 ? 114.344 148.805 93.009  1.00 65.58  ? 357  GLU B N   1 
ATOM   6580  C CA  . GLU B 1 357 ? 113.464 149.908 93.383  1.00 65.58  ? 357  GLU B CA  1 
ATOM   6581  C C   . GLU B 1 357 ? 112.009 149.585 93.059  1.00 65.58  ? 357  GLU B C   1 
ATOM   6582  O O   . GLU B 1 357 ? 111.104 149.957 93.814  1.00 65.58  ? 357  GLU B O   1 
ATOM   6583  C CB  . GLU B 1 357 ? 113.901 151.217 92.718  1.00 65.58  ? 357  GLU B CB  1 
ATOM   6584  C CG  . GLU B 1 357 ? 113.985 151.223 91.206  1.00 65.58  ? 357  GLU B CG  1 
ATOM   6585  C CD  . GLU B 1 357 ? 114.924 152.295 90.683  1.00 65.58  ? 357  GLU B CD  1 
ATOM   6586  O OE1 . GLU B 1 357 ? 115.643 152.033 89.699  1.00 65.58  ? 357  GLU B OE1 1 
ATOM   6587  O OE2 . GLU B 1 357 ? 114.955 153.397 91.268  1.00 65.58  ? 357  GLU B OE2 1 
ATOM   6588  N N   . TRP B 1 358 ? 111.760 148.888 91.951  1.00 66.42  ? 358  TRP B N   1 
ATOM   6589  C CA  . TRP B 1 358 ? 110.416 148.433 91.629  1.00 66.42  ? 358  TRP B CA  1 
ATOM   6590  C C   . TRP B 1 358 ? 110.278 146.924 91.698  1.00 66.42  ? 358  TRP B C   1 
ATOM   6591  O O   . TRP B 1 358 ? 109.161 146.411 91.573  1.00 66.42  ? 358  TRP B O   1 
ATOM   6592  C CB  . TRP B 1 358 ? 110.002 148.904 90.228  1.00 66.42  ? 358  TRP B CB  1 
ATOM   6593  C CG  . TRP B 1 358 ? 110.572 150.226 89.809  1.00 66.42  ? 358  TRP B CG  1 
ATOM   6594  C CD1 . TRP B 1 358 ? 111.373 150.459 88.732  1.00 66.42  ? 358  TRP B CD1 1 
ATOM   6595  C CD2 . TRP B 1 358 ? 110.372 151.499 90.442  1.00 66.42  ? 358  TRP B CD2 1 
ATOM   6596  N NE1 . TRP B 1 358 ? 111.694 151.790 88.657  1.00 66.42  ? 358  TRP B NE1 1 
ATOM   6597  C CE2 . TRP B 1 358 ? 111.089 152.452 89.692  1.00 66.42  ? 358  TRP B CE2 1 
ATOM   6598  C CE3 . TRP B 1 358 ? 109.660 151.926 91.568  1.00 66.42  ? 358  TRP B CE3 1 
ATOM   6599  C CZ2 . TRP B 1 358 ? 111.121 153.802 90.035  1.00 66.42  ? 358  TRP B CZ2 1 
ATOM   6600  C CZ3 . TRP B 1 358 ? 109.692 153.266 91.905  1.00 66.42  ? 358  TRP B CZ3 1 
ATOM   6601  C CH2 . TRP B 1 358 ? 110.416 154.188 91.141  1.00 66.42  ? 358  TRP B CH2 1 
ATOM   6602  N N   . PHE B 1 359 ? 111.390 146.213 91.883  1.00 63.19  ? 359  PHE B N   1 
ATOM   6603  C CA  . PHE B 1 359 ? 111.352 144.759 91.974  1.00 63.19  ? 359  PHE B CA  1 
ATOM   6604  C C   . PHE B 1 359 ? 110.751 144.306 93.300  1.00 63.19  ? 359  PHE B C   1 
ATOM   6605  O O   . PHE B 1 359 ? 110.054 143.287 93.362  1.00 63.19  ? 359  PHE B O   1 
ATOM   6606  C CB  . PHE B 1 359 ? 112.765 144.199 91.793  1.00 63.19  ? 359  PHE B CB  1 
ATOM   6607  C CG  . PHE B 1 359 ? 112.823 142.703 91.675  1.00 63.19  ? 359  PHE B CG  1 
ATOM   6608  C CD1 . PHE B 1 359 ? 113.918 142.007 92.157  1.00 63.19  ? 359  PHE B CD1 1 
ATOM   6609  C CD2 . PHE B 1 359 ? 111.804 141.992 91.065  1.00 63.19  ? 359  PHE B CD2 1 
ATOM   6610  C CE1 . PHE B 1 359 ? 113.979 140.638 92.060  1.00 63.19  ? 359  PHE B CE1 1 
ATOM   6611  C CE2 . PHE B 1 359 ? 111.865 140.617 90.965  1.00 63.19  ? 359  PHE B CE2 1 
ATOM   6612  C CZ  . PHE B 1 359 ? 112.957 139.939 91.460  1.00 63.19  ? 359  PHE B CZ  1 
ATOM   6613  N N   . ILE B 1 360 ? 110.995 145.057 94.373  1.00 64.48  ? 360  ILE B N   1 
ATOM   6614  C CA  . ILE B 1 360 ? 110.648 144.549 95.693  1.00 64.48  ? 360  ILE B CA  1 
ATOM   6615  C C   . ILE B 1 360 ? 109.192 144.831 96.068  1.00 64.48  ? 360  ILE B C   1 
ATOM   6616  O O   . ILE B 1 360 ? 108.558 143.995 96.725  1.00 64.48  ? 360  ILE B O   1 
ATOM   6617  C CB  . ILE B 1 360 ? 111.645 145.109 96.731  1.00 64.48  ? 360  ILE B CB  1 
ATOM   6618  C CG1 . ILE B 1 360 ? 111.416 144.495 98.113  1.00 64.48  ? 360  ILE B CG1 1 
ATOM   6619  C CG2 . ILE B 1 360 ? 111.601 146.632 96.803  1.00 64.48  ? 360  ILE B CG2 1 
ATOM   6620  C CD1 . ILE B 1 360 ? 111.676 143.014 98.137  1.00 64.48  ? 360  ILE B CD1 1 
ATOM   6621  N N   . LYS B 1 361 ? 108.609 145.944 95.615  1.00 67.71  ? 361  LYS B N   1 
ATOM   6622  C CA  . LYS B 1 361 ? 107.391 146.428 96.256  1.00 67.71  ? 361  LYS B CA  1 
ATOM   6623  C C   . LYS B 1 361 ? 106.158 146.115 95.412  1.00 67.71  ? 361  LYS B C   1 
ATOM   6624  O O   . LYS B 1 361 ? 105.070 145.868 95.946  1.00 67.71  ? 361  LYS B O   1 
ATOM   6625  C CB  . LYS B 1 361 ? 107.536 147.931 96.544  1.00 67.71  ? 361  LYS B CB  1 
ATOM   6626  C CG  . LYS B 1 361 ? 106.259 148.705 96.850  1.00 67.71  ? 361  LYS B CG  1 
ATOM   6627  C CD  . LYS B 1 361 ? 106.574 150.149 97.203  1.00 67.71  ? 361  LYS B CD  1 
ATOM   6628  C CE  . LYS B 1 361 ? 105.484 150.754 98.076  1.00 67.71  ? 361  LYS B CE  1 
ATOM   6629  N NZ  . LYS B 1 361 ? 105.960 151.964 98.803  1.00 67.71  ? 361  LYS B NZ  1 
ATOM   6630  N N   . HIS B 1 362 ? 106.316 146.049 94.091  1.00 71.03  ? 362  HIS B N   1 
ATOM   6631  C CA  . HIS B 1 362 ? 105.165 145.734 93.248  1.00 71.03  ? 362  HIS B CA  1 
ATOM   6632  C C   . HIS B 1 362 ? 105.416 144.675 92.188  1.00 71.03  ? 362  HIS B C   1 
ATOM   6633  O O   . HIS B 1 362 ? 104.443 144.197 91.594  1.00 71.03  ? 362  HIS B O   1 
ATOM   6634  C CB  . HIS B 1 362 ? 104.634 147.001 92.569  1.00 71.03  ? 362  HIS B CB  1 
ATOM   6635  C CG  . HIS B 1 362 ? 103.499 147.643 93.306  1.00 71.03  ? 362  HIS B CG  1 
ATOM   6636  N ND1 . HIS B 1 362 ? 102.190 147.236 93.156  1.00 71.03  ? 362  HIS B ND1 1 
ATOM   6637  C CD2 . HIS B 1 362 ? 103.478 148.651 94.209  1.00 71.03  ? 362  HIS B CD2 1 
ATOM   6638  C CE1 . HIS B 1 362 ? 101.411 147.972 93.929  1.00 71.03  ? 362  HIS B CE1 1 
ATOM   6639  N NE2 . HIS B 1 362 ? 102.168 148.838 94.578  1.00 71.03  ? 362  HIS B NE2 1 
ATOM   6640  N N   . LEU B 1 363 ? 106.660 144.275 91.923  1.00 66.54  ? 363  LEU B N   1 
ATOM   6641  C CA  . LEU B 1 363 ? 106.894 143.266 90.897  1.00 66.54  ? 363  LEU B CA  1 
ATOM   6642  C C   . LEU B 1 363 ? 106.646 141.867 91.449  1.00 66.54  ? 363  LEU B C   1 
ATOM   6643  O O   . LEU B 1 363 ? 105.696 141.187 91.045  1.00 66.54  ? 363  LEU B O   1 
ATOM   6644  C CB  . LEU B 1 363 ? 108.321 143.393 90.359  1.00 66.54  ? 363  LEU B CB  1 
ATOM   6645  C CG  . LEU B 1 363 ? 108.696 142.859 88.971  1.00 66.54  ? 363  LEU B CG  1 
ATOM   6646  C CD1 . LEU B 1 363 ? 109.895 143.639 88.458  1.00 66.54  ? 363  LEU B CD1 1 
ATOM   6647  C CD2 . LEU B 1 363 ? 108.981 141.363 88.928  1.00 66.54  ? 363  LEU B CD2 1 
ATOM   6648  N N   . ALA B 1 364 ? 107.486 141.426 92.386  1.00 62.67  ? 364  ALA B N   1 
ATOM   6649  C CA  . ALA B 1 364 ? 107.404 140.062 92.889  1.00 62.67  ? 364  ALA B CA  1 
ATOM   6650  C C   . ALA B 1 364 ? 106.365 139.899 93.987  1.00 62.67  ? 364  ALA B C   1 
ATOM   6651  O O   . ALA B 1 364 ? 106.115 138.769 94.422  1.00 62.67  ? 364  ALA B O   1 
ATOM   6652  C CB  . ALA B 1 364 ? 108.771 139.608 93.408  1.00 62.67  ? 364  ALA B CB  1 
ATOM   6653  N N   . GLY B 1 365 ? 105.759 140.989 94.443  1.00 61.81  ? 365  GLY B N   1 
ATOM   6654  C CA  . GLY B 1 365 ? 104.808 140.920 95.532  1.00 61.81  ? 365  GLY B CA  1 
ATOM   6655  C C   . GLY B 1 365 ? 105.271 141.703 96.742  1.00 61.81  ? 365  GLY B C   1 
ATOM   6656  O O   . GLY B 1 365 ? 105.893 142.760 96.602  1.00 61.81  ? 365  GLY B O   1 
ATOM   6657  N N   . GLU B 1 366 ? 104.984 141.192 97.939  1.00 67.88  ? 366  GLU B N   1 
ATOM   6658  C CA  . GLU B 1 366 ? 105.320 141.908 99.160  1.00 67.88  ? 366  GLU B CA  1 
ATOM   6659  C C   . GLU B 1 366 ? 106.394 141.225 99.995  1.00 67.88  ? 366  GLU B C   1 
ATOM   6660  O O   . GLU B 1 366 ? 106.692 141.711 101.090 1.00 67.88  ? 366  GLU B O   1 
ATOM   6661  C CB  . GLU B 1 366 ? 104.068 142.100 100.034 1.00 67.88  ? 366  GLU B CB  1 
ATOM   6662  C CG  . GLU B 1 366 ? 102.981 143.013 99.469  1.00 67.88  ? 366  GLU B CG  1 
ATOM   6663  C CD  . GLU B 1 366 ? 103.514 144.128 98.592  1.00 67.88  ? 366  GLU B CD  1 
ATOM   6664  O OE1 . GLU B 1 366 ? 103.351 144.037 97.359  1.00 67.88  ? 366  GLU B OE1 1 
ATOM   6665  O OE2 . GLU B 1 366 ? 104.097 145.092 99.131  1.00 67.88  ? 366  GLU B OE2 1 
ATOM   6666  N N   . ASN B 1 367 ? 106.984 140.132 99.524  1.00 69.65  ? 367  ASN B N   1 
ATOM   6667  C CA  . ASN B 1 367 ? 107.880 139.334 100.349 1.00 69.65  ? 367  ASN B CA  1 
ATOM   6668  C C   . ASN B 1 367 ? 109.308 139.873 100.253 1.00 69.65  ? 367  ASN B C   1 
ATOM   6669  O O   . ASN B 1 367 ? 109.590 140.849 99.552  1.00 69.65  ? 367  ASN B O   1 
ATOM   6670  C CB  . ASN B 1 367 ? 107.794 137.867 99.938  1.00 69.65  ? 367  ASN B CB  1 
ATOM   6671  C CG  . ASN B 1 367 ? 106.451 137.249 100.271 1.00 69.65  ? 367  ASN B CG  1 
ATOM   6672  O OD1 . ASN B 1 367 ? 105.895 137.486 101.343 1.00 69.65  ? 367  ASN B OD1 1 
ATOM   6673  N ND2 . ASN B 1 367 ? 105.920 136.454 99.350  1.00 69.65  ? 367  ASN B ND2 1 
ATOM   6674  N N   . ARG B 1 368 ? 110.226 139.233 100.973 1.00 64.36  ? 368  ARG B N   1 
ATOM   6675  C CA  . ARG B 1 368 ? 111.648 139.544 100.928 1.00 64.36  ? 368  ARG B CA  1 
ATOM   6676  C C   . ARG B 1 368 ? 112.500 138.378 100.463 1.00 64.36  ? 368  ARG B C   1 
ATOM   6677  O O   . ARG B 1 368 ? 113.550 138.601 99.858  1.00 64.36  ? 368  ARG B O   1 
ATOM   6678  C CB  . ARG B 1 368 ? 112.148 139.990 102.311 1.00 64.36  ? 368  ARG B CB  1 
ATOM   6679  C CG  . ARG B 1 368 ? 112.140 141.491 102.540 1.00 64.36  ? 368  ARG B CG  1 
ATOM   6680  C CD  . ARG B 1 368 ? 112.974 142.220 101.496 1.00 64.36  ? 368  ARG B CD  1 
ATOM   6681  N NE  . ARG B 1 368 ? 114.406 141.985 101.651 1.00 64.36  ? 368  ARG B NE  1 
ATOM   6682  C CZ  . ARG B 1 368 ? 115.150 141.314 100.779 1.00 64.36  ? 368  ARG B CZ  1 
ATOM   6683  N NH1 . ARG B 1 368 ? 114.597 140.805 99.689  1.00 64.36  ? 368  ARG B NH1 1 
ATOM   6684  N NH2 . ARG B 1 368 ? 116.446 141.148 100.997 1.00 64.36  ? 368  ARG B NH2 1 
ATOM   6685  N N   . ARG B 1 369 ? 112.075 137.145 100.729 1.00 62.07  ? 369  ARG B N   1 
ATOM   6686  C CA  . ARG B 1 369 ? 112.770 135.943 100.289 1.00 62.07  ? 369  ARG B CA  1 
ATOM   6687  C C   . ARG B 1 369 ? 112.243 135.419 98.962  1.00 62.07  ? 369  ARG B C   1 
ATOM   6688  O O   . ARG B 1 369 ? 113.011 134.862 98.172  1.00 62.07  ? 369  ARG B O   1 
ATOM   6689  C CB  . ARG B 1 369 ? 112.648 134.843 101.352 1.00 62.07  ? 369  ARG B CB  1 
ATOM   6690  C CG  . ARG B 1 369 ? 113.655 134.907 102.513 1.00 62.07  ? 369  ARG B CG  1 
ATOM   6691  C CD  . ARG B 1 369 ? 115.118 135.145 102.107 1.00 62.07  ? 369  ARG B CD  1 
ATOM   6692  N NE  . ARG B 1 369 ? 115.578 134.312 100.995 1.00 62.07  ? 369  ARG B NE  1 
ATOM   6693  C CZ  . ARG B 1 369 ? 116.670 134.564 100.279 1.00 62.07  ? 369  ARG B CZ  1 
ATOM   6694  N NH1 . ARG B 1 369 ? 117.425 135.616 100.568 1.00 62.07  ? 369  ARG B NH1 1 
ATOM   6695  N NH2 . ARG B 1 369 ? 117.016 133.759 99.284  1.00 62.07  ? 369  ARG B NH2 1 
ATOM   6696  N N   . LYS B 1 370 ? 110.940 135.575 98.711  1.00 64.73  ? 370  LYS B N   1 
ATOM   6697  C CA  . LYS B 1 370 ? 110.378 135.213 97.415  1.00 64.73  ? 370  LYS B CA  1 
ATOM   6698  C C   . LYS B 1 370 ? 110.866 136.150 96.319  1.00 64.73  ? 370  LYS B C   1 
ATOM   6699  O O   . LYS B 1 370 ? 111.092 135.715 95.184  1.00 64.73  ? 370  LYS B O   1 
ATOM   6700  C CB  . LYS B 1 370 ? 108.850 135.217 97.499  1.00 64.73  ? 370  LYS B CB  1 
ATOM   6701  C CG  . LYS B 1 370 ? 108.127 134.773 96.238  1.00 64.73  ? 370  LYS B CG  1 
ATOM   6702  C CD  . LYS B 1 370 ? 107.248 135.890 95.699  1.00 64.73  ? 370  LYS B CD  1 
ATOM   6703  C CE  . LYS B 1 370 ? 106.140 135.348 94.814  1.00 64.73  ? 370  LYS B CE  1 
ATOM   6704  N NZ  . LYS B 1 370 ? 105.307 136.441 94.243  1.00 64.73  ? 370  LYS B NZ  1 
ATOM   6705  N N   . ALA B 1 371 ? 111.058 137.430 96.645  1.00 61.00  ? 371  ALA B N   1 
ATOM   6706  C CA  . ALA B 1 371 ? 111.646 138.359 95.687  1.00 61.00  ? 371  ALA B CA  1 
ATOM   6707  C C   . ALA B 1 371 ? 113.129 138.084 95.476  1.00 61.00  ? 371  ALA B C   1 
ATOM   6708  O O   . ALA B 1 371 ? 113.679 138.429 94.425  1.00 61.00  ? 371  ALA B O   1 
ATOM   6709  C CB  . ALA B 1 371 ? 111.434 139.798 96.153  1.00 61.00  ? 371  ALA B CB  1 
ATOM   6710  N N   . MET B 1 372 ? 113.788 137.466 96.454  1.00 61.83  ? 372  MET B N   1 
ATOM   6711  C CA  . MET B 1 372 ? 115.211 137.182 96.324  1.00 61.83  ? 372  MET B CA  1 
ATOM   6712  C C   . MET B 1 372 ? 115.452 135.915 95.512  1.00 61.83  ? 372  MET B C   1 
ATOM   6713  O O   . MET B 1 372 ? 116.458 135.812 94.805  1.00 61.83  ? 372  MET B O   1 
ATOM   6714  C CB  . MET B 1 372 ? 115.838 137.044 97.711  1.00 61.83  ? 372  MET B CB  1 
ATOM   6715  C CG  . MET B 1 372 ? 117.238 137.624 97.870  1.00 61.83  ? 372  MET B CG  1 
ATOM   6716  S SD  . MET B 1 372 ? 117.360 139.404 97.602  1.00 61.83  ? 372  MET B SD  1 
ATOM   6717  C CE  . MET B 1 372 ? 118.192 139.455 96.024  1.00 61.83  ? 372  MET B CE  1 
ATOM   6718  N N   . LYS B 1 373 ? 114.533 134.949 95.596  1.00 60.99  ? 373  LYS B N   1 
ATOM   6719  C CA  . LYS B 1 373 ? 114.767 133.628 95.019  1.00 60.99  ? 373  LYS B CA  1 
ATOM   6720  C C   . LYS B 1 373 ? 114.644 133.649 93.498  1.00 60.99  ? 373  LYS B C   1 
ATOM   6721  O O   . LYS B 1 373 ? 115.243 132.810 92.814  1.00 60.99  ? 373  LYS B O   1 
ATOM   6722  C CB  . LYS B 1 373 ? 113.794 132.626 95.661  1.00 60.99  ? 373  LYS B CB  1 
ATOM   6723  C CG  . LYS B 1 373 ? 113.864 131.165 95.199  1.00 60.99  ? 373  LYS B CG  1 
ATOM   6724  C CD  . LYS B 1 373 ? 112.735 130.817 94.232  1.00 60.99  ? 373  LYS B CD  1 
ATOM   6725  C CE  . LYS B 1 373 ? 111.371 131.054 94.865  1.00 60.99  ? 373  LYS B CE  1 
ATOM   6726  N NZ  . LYS B 1 373 ? 110.269 130.916 93.877  1.00 60.99  ? 373  LYS B NZ  1 
ATOM   6727  N N   . TYR B 1 374 ? 113.923 134.632 92.947  1.00 64.37  ? 374  TYR B N   1 
ATOM   6728  C CA  . TYR B 1 374 ? 113.726 134.709 91.500  1.00 64.37  ? 374  TYR B CA  1 
ATOM   6729  C C   . TYR B 1 374 ? 114.986 135.088 90.730  1.00 64.37  ? 374  TYR B C   1 
ATOM   6730  O O   . TYR B 1 374 ? 114.989 134.991 89.498  1.00 64.37  ? 374  TYR B O   1 
ATOM   6731  C CB  . TYR B 1 374 ? 112.623 135.714 91.158  1.00 64.37  ? 374  TYR B CB  1 
ATOM   6732  C CG  . TYR B 1 374 ? 111.213 135.216 91.369  1.00 64.37  ? 374  TYR B CG  1 
ATOM   6733  C CD1 . TYR B 1 374 ? 110.951 133.865 91.576  1.00 64.37  ? 374  TYR B CD1 1 
ATOM   6734  C CD2 . TYR B 1 374 ? 110.136 136.096 91.326  1.00 64.37  ? 374  TYR B CD2 1 
ATOM   6735  C CE1 . TYR B 1 374 ? 109.655 133.408 91.756  1.00 64.37  ? 374  TYR B CE1 1 
ATOM   6736  C CE2 . TYR B 1 374 ? 108.837 135.648 91.504  1.00 64.37  ? 374  TYR B CE2 1 
ATOM   6737  C CZ  . TYR B 1 374 ? 108.604 134.302 91.718  1.00 64.37  ? 374  TYR B CZ  1 
ATOM   6738  O OH  . TYR B 1 374 ? 107.317 133.850 91.896  1.00 64.37  ? 374  TYR B OH  1 
ATOM   6739  N N   . LEU B 1 375 ? 116.048 135.534 91.405  1.00 61.50  ? 375  LEU B N   1 
ATOM   6740  C CA  . LEU B 1 375 ? 117.221 135.994 90.672  1.00 61.50  ? 375  LEU B CA  1 
ATOM   6741  C C   . LEU B 1 375 ? 118.538 135.639 91.361  1.00 61.50  ? 375  LEU B C   1 
ATOM   6742  O O   . LEU B 1 375 ? 119.589 136.162 90.970  1.00 61.50  ? 375  LEU B O   1 
ATOM   6743  C CB  . LEU B 1 375 ? 117.120 137.509 90.435  1.00 61.50  ? 375  LEU B CB  1 
ATOM   6744  C CG  . LEU B 1 375 ? 117.476 138.583 91.473  1.00 61.50  ? 375  LEU B CG  1 
ATOM   6745  C CD1 . LEU B 1 375 ? 117.308 139.959 90.840  1.00 61.50  ? 375  LEU B CD1 1 
ATOM   6746  C CD2 . LEU B 1 375 ? 116.696 138.470 92.765  1.00 61.50  ? 375  LEU B CD2 1 
ATOM   6747  N N   . LYS B 1 376 ? 118.527 134.742 92.348  1.00 59.64  ? 376  LYS B N   1 
ATOM   6748  C CA  . LYS B 1 376 ? 119.733 134.454 93.112  1.00 59.64  ? 376  LYS B CA  1 
ATOM   6749  C C   . LYS B 1 376 ? 120.181 133.015 92.914  1.00 59.64  ? 376  LYS B C   1 
ATOM   6750  O O   . LYS B 1 376 ? 119.632 132.112 93.565  1.00 59.64  ? 376  LYS B O   1 
ATOM   6751  C CB  . LYS B 1 376 ? 119.500 134.719 94.594  1.00 59.64  ? 376  LYS B CB  1 
ATOM   6752  C CG  . LYS B 1 376 ? 119.755 136.147 95.037  1.00 59.64  ? 376  LYS B CG  1 
ATOM   6753  C CD  . LYS B 1 376 ? 121.221 136.362 95.365  1.00 59.64  ? 376  LYS B CD  1 
ATOM   6754  C CE  . LYS B 1 376 ? 121.425 137.620 96.196  1.00 59.64  ? 376  LYS B CE  1 
ATOM   6755  N NZ  . LYS B 1 376 ? 121.096 137.401 97.633  1.00 59.64  ? 376  LYS B NZ  1 
ATOM   6756  N N   . PRO B 1 377 ? 121.151 132.745 92.039  1.00 63.21  ? 377  PRO B N   1 
ATOM   6757  C CA  . PRO B 1 377 ? 121.987 131.552 92.224  1.00 63.21  ? 377  PRO B CA  1 
ATOM   6758  C C   . PRO B 1 377 ? 123.090 131.857 93.223  1.00 63.21  ? 377  PRO B C   1 
ATOM   6759  O O   . PRO B 1 377 ? 123.292 133.034 93.544  1.00 63.21  ? 377  PRO B O   1 
ATOM   6760  C CB  . PRO B 1 377 ? 122.535 131.280 90.819  1.00 63.21  ? 377  PRO B CB  1 
ATOM   6761  C CG  . PRO B 1 377 ? 122.536 132.612 90.161  1.00 63.21  ? 377  PRO B CG  1 
ATOM   6762  C CD  . PRO B 1 377 ? 121.360 133.367 90.722  1.00 63.21  ? 377  PRO B CD  1 
ATOM   6763  N N   . HIS B 1 378 ? 123.825 130.829 93.676  1.00 66.29  ? 378  HIS B N   1 
ATOM   6764  C CA  . HIS B 1 378 ? 124.665 130.887 94.881  1.00 66.29  ? 378  HIS B CA  1 
ATOM   6765  C C   . HIS B 1 378 ? 123.890 131.470 96.057  1.00 66.29  ? 378  HIS B C   1 
ATOM   6766  O O   . HIS B 1 378 ? 124.344 132.427 96.690  1.00 66.29  ? 378  HIS B O   1 
ATOM   6767  C CB  . HIS B 1 378 ? 125.966 131.671 94.646  1.00 66.29  ? 378  HIS B CB  1 
ATOM   6768  C CG  . HIS B 1 378 ? 127.079 131.303 95.581  1.00 66.29  ? 378  HIS B CG  1 
ATOM   6769  N ND1 . HIS B 1 378 ? 126.929 131.280 96.952  1.00 66.29  ? 378  HIS B ND1 1 
ATOM   6770  C CD2 . HIS B 1 378 ? 128.363 130.948 95.339  1.00 66.29  ? 378  HIS B CD2 1 
ATOM   6771  C CE1 . HIS B 1 378 ? 128.070 130.923 97.512  1.00 66.29  ? 378  HIS B CE1 1 
ATOM   6772  N NE2 . HIS B 1 378 ? 128.957 130.716 96.556  1.00 66.29  ? 378  HIS B NE2 1 
ATOM   6773  N N   . HIS B 1 379 ? 122.717 130.882 96.318  1.00 62.08  ? 379  HIS B N   1 
ATOM   6774  C CA  . HIS B 1 379 ? 121.611 131.456 97.081  1.00 62.08  ? 379  HIS B CA  1 
ATOM   6775  C C   . HIS B 1 379 ? 121.983 131.973 98.467  1.00 62.08  ? 379  HIS B C   1 
ATOM   6776  O O   . HIS B 1 379 ? 121.964 133.187 98.698  1.00 62.08  ? 379  HIS B O   1 
ATOM   6777  C CB  . HIS B 1 379 ? 120.478 130.423 97.200  1.00 62.08  ? 379  HIS B CB  1 
ATOM   6778  C CG  . HIS B 1 379 ? 120.946 129.016 97.435  1.00 62.08  ? 379  HIS B CG  1 
ATOM   6779  N ND1 . HIS B 1 379 ? 120.981 128.444 98.689  1.00 62.08  ? 379  HIS B ND1 1 
ATOM   6780  C CD2 . HIS B 1 379 ? 121.372 128.058 96.576  1.00 62.08  ? 379  HIS B CD2 1 
ATOM   6781  C CE1 . HIS B 1 379 ? 121.425 127.204 98.595  1.00 62.08  ? 379  HIS B CE1 1 
ATOM   6782  N NE2 . HIS B 1 379 ? 121.670 126.945 97.323  1.00 62.08  ? 379  HIS B NE2 1 
ATOM   6783  N N   . ARG B 1 380 ? 122.373 131.070 99.364  1.00 56.79  ? 380  ARG B N   1 
ATOM   6784  C CA  . ARG B 1 380 ? 122.633 131.391 100.761 1.00 56.79  ? 380  ARG B CA  1 
ATOM   6785  C C   . ARG B 1 380 ? 123.327 130.192 101.395 1.00 56.79  ? 380  ARG B C   1 
ATOM   6786  O O   . ARG B 1 380 ? 123.008 129.046 101.065 1.00 56.79  ? 380  ARG B O   1 
ATOM   6787  C CB  . ARG B 1 380 ? 121.318 131.732 101.487 1.00 56.79  ? 380  ARG B CB  1 
ATOM   6788  C CG  . ARG B 1 380 ? 121.420 132.019 102.982 1.00 56.79  ? 380  ARG B CG  1 
ATOM   6789  C CD  . ARG B 1 380 ? 122.457 133.089 103.308 1.00 56.79  ? 380  ARG B CD  1 
ATOM   6790  N NE  . ARG B 1 380 ? 122.422 133.476 104.718 1.00 56.79  ? 380  ARG B NE  1 
ATOM   6791  C CZ  . ARG B 1 380 ? 121.588 134.378 105.226 1.00 56.79  ? 380  ARG B CZ  1 
ATOM   6792  N NH1 . ARG B 1 380 ? 120.716 134.995 104.442 1.00 56.79  ? 380  ARG B NH1 1 
ATOM   6793  N NH2 . ARG B 1 380 ? 121.626 134.667 106.520 1.00 56.79  ? 380  ARG B NH2 1 
ATOM   6794  N N   . LYS B 1 381 ? 124.277 130.431 102.296 1.00 53.08  ? 381  LYS B N   1 
ATOM   6795  C CA  . LYS B 1 381 ? 124.870 129.339 103.051 1.00 53.08  ? 381  LYS B CA  1 
ATOM   6796  C C   . LYS B 1 381 ? 123.948 128.935 104.196 1.00 53.08  ? 381  LYS B C   1 
ATOM   6797  O O   . LYS B 1 381 ? 122.790 129.351 104.277 1.00 53.08  ? 381  LYS B O   1 
ATOM   6798  C CB  . LYS B 1 381 ? 126.234 129.736 103.602 1.00 53.08  ? 381  LYS B CB  1 
ATOM   6799  C CG  . LYS B 1 381 ? 127.290 129.953 102.546 1.00 53.08  ? 381  LYS B CG  1 
ATOM   6800  C CD  . LYS B 1 381 ? 128.595 130.366 103.188 1.00 53.08  ? 381  LYS B CD  1 
ATOM   6801  C CE  . LYS B 1 381 ? 129.675 130.564 102.143 1.00 53.08  ? 381  LYS B CE  1 
ATOM   6802  N NZ  . LYS B 1 381 ? 130.942 130.992 102.785 1.00 53.08  ? 381  LYS B NZ  1 
ATOM   6803  N N   . GLU B 1 382 ? 124.468 128.112 105.099 1.00 48.50  ? 382  GLU B N   1 
ATOM   6804  C CA  . GLU B 1 382 ? 123.638 127.710 106.220 1.00 48.50  ? 382  GLU B CA  1 
ATOM   6805  C C   . GLU B 1 382 ? 123.512 128.854 107.225 1.00 48.50  ? 382  GLU B C   1 
ATOM   6806  O O   . GLU B 1 382 ? 124.459 129.601 107.485 1.00 48.50  ? 382  GLU B O   1 
ATOM   6807  C CB  . GLU B 1 382 ? 124.200 126.459 106.897 1.00 48.50  ? 382  GLU B CB  1 
ATOM   6808  C CG  . GLU B 1 382 ? 123.144 125.676 107.664 1.00 48.50  ? 382  GLU B CG  1 
ATOM   6809  C CD  . GLU B 1 382 ? 123.100 126.032 109.137 1.00 48.50  ? 382  GLU B CD  1 
ATOM   6810  O OE1 . GLU B 1 382 ? 122.158 125.595 109.828 1.00 48.50  ? 382  GLU B OE1 1 
ATOM   6811  O OE2 . GLU B 1 382 ? 124.018 126.733 109.609 1.00 48.50  ? 382  GLU B OE2 1 
ATOM   6812  N N   . SER B 1 383 ? 122.308 129.000 107.772 1.00 46.07  ? 383  SER B N   1 
ATOM   6813  C CA  . SER B 1 383 ? 122.053 130.002 108.801 1.00 46.07  ? 383  SER B CA  1 
ATOM   6814  C C   . SER B 1 383 ? 122.718 129.535 110.084 1.00 46.07  ? 383  SER B C   1 
ATOM   6815  O O   . SER B 1 383 ? 122.180 128.680 110.795 1.00 46.07  ? 383  SER B O   1 
ATOM   6816  C CB  . SER B 1 383 ? 120.554 130.202 109.004 1.00 46.07  ? 383  SER B CB  1 
ATOM   6817  O OG  . SER B 1 383 ? 120.045 129.266 109.938 1.00 46.07  ? 383  SER B OG  1 
ATOM   6818  N N   . HIS B 1 384 ? 123.877 130.104 110.396 1.00 36.53  ? 384  HIS B N   1 
ATOM   6819  C CA  . HIS B 1 384 ? 124.669 129.637 111.530 1.00 36.53  ? 384  HIS B CA  1 
ATOM   6820  C C   . HIS B 1 384 ? 124.273 130.334 112.824 1.00 36.53  ? 384  HIS B C   1 
ATOM   6821  O O   . HIS B 1 384 ? 125.103 130.811 113.596 1.00 36.53  ? 384  HIS B O   1 
ATOM   6822  C CB  . HIS B 1 384 ? 126.147 129.824 111.231 1.00 36.53  ? 384  HIS B CB  1 
ATOM   6823  C CG  . HIS B 1 384 ? 126.668 128.879 110.197 1.00 36.53  ? 384  HIS B CG  1 
ATOM   6824  N ND1 . HIS B 1 384 ? 126.573 129.127 108.846 1.00 36.53  ? 384  HIS B ND1 1 
ATOM   6825  C CD2 . HIS B 1 384 ? 127.275 127.675 110.317 1.00 36.53  ? 384  HIS B CD2 1 
ATOM   6826  C CE1 . HIS B 1 384 ? 127.107 128.120 108.177 1.00 36.53  ? 384  HIS B CE1 1 
ATOM   6827  N NE2 . HIS B 1 384 ? 127.542 127.227 109.047 1.00 36.53  ? 384  HIS B NE2 1 
ATOM   6828  N N   . SER B 1 385 ? 122.964 130.359 113.067 1.00 27.21  ? 385  SER B N   1 
ATOM   6829  C CA  . SER B 1 385 ? 122.388 130.668 114.361 1.00 27.21  ? 385  SER B CA  1 
ATOM   6830  C C   . SER B 1 385 ? 122.103 129.402 115.141 1.00 27.21  ? 385  SER B C   1 
ATOM   6831  O O   . SER B 1 385 ? 121.367 129.436 116.127 1.00 27.21  ? 385  SER B O   1 
ATOM   6832  C CB  . SER B 1 385 ? 121.111 131.483 114.194 1.00 27.21  ? 385  SER B CB  1 
ATOM   6833  O OG  . SER B 1 385 ? 120.044 130.653 113.782 1.00 27.21  ? 385  SER B OG  1 
ATOM   6834  N N   . VAL B 1 386 ? 122.647 128.278 114.687 1.00 18.34  ? 386  VAL B N   1 
ATOM   6835  C CA  . VAL B 1 386 ? 122.552 127.025 115.416 1.00 18.34  ? 386  VAL B CA  1 
ATOM   6836  C C   . VAL B 1 386 ? 123.919 126.436 115.716 1.00 18.34  ? 386  VAL B C   1 
ATOM   6837  O O   . VAL B 1 386 ? 124.029 125.597 116.614 1.00 18.34  ? 386  VAL B O   1 
ATOM   6838  C CB  . VAL B 1 386 ? 121.676 126.006 114.651 1.00 18.34  ? 386  VAL B CB  1 
ATOM   6839  C CG1 . VAL B 1 386 ? 122.441 125.354 113.514 1.00 18.34  ? 386  VAL B CG1 1 
ATOM   6840  C CG2 . VAL B 1 386 ? 121.030 124.993 115.576 1.00 18.34  ? 386  VAL B CG2 1 
ATOM   6841  N N   . THR B 1 387 ? 124.984 126.869 115.041 1.00 12.11  ? 387  THR B N   1 
ATOM   6842  C CA  . THR B 1 387 ? 126.321 126.537 115.510 1.00 12.11  ? 387  THR B CA  1 
ATOM   6843  C C   . THR B 1 387 ? 126.663 127.366 116.735 1.00 12.11  ? 387  THR B C   1 
ATOM   6844  O O   . THR B 1 387 ? 127.454 126.944 117.584 1.00 12.11  ? 387  THR B O   1 
ATOM   6845  C CB  . THR B 1 387 ? 127.328 126.776 114.394 1.00 12.11  ? 387  THR B CB  1 
ATOM   6846  O OG1 . THR B 1 387 ? 126.831 126.188 113.192 1.00 12.11  ? 387  THR B OG1 1 
ATOM   6847  C CG2 . THR B 1 387 ? 128.651 126.110 114.708 1.00 12.11  ? 387  THR B CG2 1 
ATOM   6848  N N   . PHE B 1 388 ? 126.046 128.537 116.851 1.00 9.67   ? 388  PHE B N   1 
ATOM   6849  C CA  . PHE B 1 388 ? 126.200 129.365 118.036 1.00 9.67   ? 388  PHE B CA  1 
ATOM   6850  C C   . PHE B 1 388 ? 125.410 128.799 119.207 1.00 9.67   ? 388  PHE B C   1 
ATOM   6851  O O   . PHE B 1 388 ? 125.920 128.737 120.328 1.00 9.67   ? 388  PHE B O   1 
ATOM   6852  C CB  . PHE B 1 388 ? 125.759 130.792 117.696 1.00 9.67   ? 388  PHE B CB  1 
ATOM   6853  C CG  . PHE B 1 388 ? 125.922 131.770 118.811 1.00 9.67   ? 388  PHE B CG  1 
ATOM   6854  C CD1 . PHE B 1 388 ? 124.843 132.130 119.591 1.00 9.67   ? 388  PHE B CD1 1 
ATOM   6855  C CD2 . PHE B 1 388 ? 127.142 132.349 119.062 1.00 9.67   ? 388  PHE B CD2 1 
ATOM   6856  C CE1 . PHE B 1 388 ? 124.988 133.023 120.607 1.00 9.67   ? 388  PHE B CE1 1 
ATOM   6857  C CE2 . PHE B 1 388 ? 127.284 133.246 120.081 1.00 9.67   ? 388  PHE B CE2 1 
ATOM   6858  C CZ  . PHE B 1 388 ? 126.206 133.578 120.854 1.00 9.67   ? 388  PHE B CZ  1 
ATOM   6859  N N   . PHE B 1 389 ? 124.188 128.351 118.969 1.00 11.53  ? 389  PHE B N   1 
ATOM   6860  C CA  . PHE B 1 389 ? 123.319 127.895 120.039 1.00 11.53  ? 389  PHE B CA  1 
ATOM   6861  C C   . PHE B 1 389 ? 123.676 126.497 120.533 1.00 11.53  ? 389  PHE B C   1 
ATOM   6862  O O   . PHE B 1 389 ? 123.282 126.125 121.640 1.00 11.53  ? 389  PHE B O   1 
ATOM   6863  C CB  . PHE B 1 389 ? 121.861 127.943 119.580 1.00 11.53  ? 389  PHE B CB  1 
ATOM   6864  C CG  . PHE B 1 389 ? 121.219 129.302 119.709 1.00 11.53  ? 389  PHE B CG  1 
ATOM   6865  C CD1 . PHE B 1 389 ? 120.075 129.465 120.469 1.00 11.53  ? 389  PHE B CD1 1 
ATOM   6866  C CD2 . PHE B 1 389 ? 121.750 130.412 119.069 1.00 11.53  ? 389  PHE B CD2 1 
ATOM   6867  C CE1 . PHE B 1 389 ? 119.480 130.704 120.588 1.00 11.53  ? 389  PHE B CE1 1 
ATOM   6868  C CE2 . PHE B 1 389 ? 121.160 131.644 119.183 1.00 11.53  ? 389  PHE B CE2 1 
ATOM   6869  C CZ  . PHE B 1 389 ? 120.028 131.792 119.944 1.00 11.53  ? 389  PHE B CZ  1 
ATOM   6870  N N   . ILE B 1 390 ? 124.389 125.704 119.730 1.00 12.58  ? 390  ILE B N   1 
ATOM   6871  C CA  . ILE B 1 390 ? 125.136 124.572 120.263 1.00 12.58  ? 390  ILE B CA  1 
ATOM   6872  C C   . ILE B 1 390 ? 126.233 125.052 121.201 1.00 12.58  ? 390  ILE B C   1 
ATOM   6873  O O   . ILE B 1 390 ? 126.369 124.518 122.307 1.00 12.58  ? 390  ILE B O   1 
ATOM   6874  C CB  . ILE B 1 390 ? 125.756 123.730 119.133 1.00 12.58  ? 390  ILE B CB  1 
ATOM   6875  C CG1 . ILE B 1 390 ? 124.695 122.990 118.350 1.00 12.58  ? 390  ILE B CG1 1 
ATOM   6876  C CG2 . ILE B 1 390 ? 126.701 122.706 119.662 1.00 12.58  ? 390  ILE B CG2 1 
ATOM   6877  C CD1 . ILE B 1 390 ? 125.201 122.515 117.021 1.00 12.58  ? 390  ILE B CD1 1 
ATOM   6878  N N   . GLY B 1 391 ? 126.978 126.079 120.816 1.00 7.51   ? 391  GLY B N   1 
ATOM   6879  C CA  . GLY B 1 391 ? 128.064 126.570 121.626 1.00 7.51   ? 391  GLY B CA  1 
ATOM   6880  C C   . GLY B 1 391 ? 127.629 127.332 122.856 1.00 7.51   ? 391  GLY B C   1 
ATOM   6881  O O   . GLY B 1 391 ? 128.305 127.253 123.883 1.00 7.51   ? 391  GLY B O   1 
ATOM   6882  N N   . LEU B 1 392 ? 126.525 128.081 122.760 1.00 8.97   ? 392  LEU B N   1 
ATOM   6883  C CA  . LEU B 1 392 ? 126.018 128.837 123.904 1.00 8.97   ? 392  LEU B CA  1 
ATOM   6884  C C   . LEU B 1 392 ? 125.653 127.907 125.045 1.00 8.97   ? 392  LEU B C   1 
ATOM   6885  O O   . LEU B 1 392 ? 125.926 128.201 126.210 1.00 8.97   ? 392  LEU B O   1 
ATOM   6886  C CB  . LEU B 1 392 ? 124.796 129.656 123.498 1.00 8.97   ? 392  LEU B CB  1 
ATOM   6887  C CG  . LEU B 1 392 ? 124.340 130.938 124.202 1.00 8.97   ? 392  LEU B CG  1 
ATOM   6888  C CD1 . LEU B 1 392 ? 123.240 131.543 123.375 1.00 8.97   ? 392  LEU B CD1 1 
ATOM   6889  C CD2 . LEU B 1 392 ? 123.855 130.784 125.631 1.00 8.97   ? 392  LEU B CD2 1 
ATOM   6890  N N   . PHE B 1 393 ? 125.051 126.770 124.722 1.00 6.96   ? 393  PHE B N   1 
ATOM   6891  C CA  . PHE B 1 393 ? 124.579 125.843 125.731 1.00 6.96   ? 393  PHE B CA  1 
ATOM   6892  C C   . PHE B 1 393 ? 125.590 124.764 126.074 1.00 6.96   ? 393  PHE B C   1 
ATOM   6893  O O   . PHE B 1 393 ? 125.443 124.117 127.111 1.00 6.96   ? 393  PHE B O   1 
ATOM   6894  C CB  . PHE B 1 393 ? 123.283 125.226 125.256 1.00 6.96   ? 393  PHE B CB  1 
ATOM   6895  C CG  . PHE B 1 393 ? 122.121 126.151 125.342 1.00 6.96   ? 393  PHE B CG  1 
ATOM   6896  C CD1 . PHE B 1 393 ? 121.629 126.541 126.570 1.00 6.96   ? 393  PHE B CD1 1 
ATOM   6897  C CD2 . PHE B 1 393 ? 121.514 126.624 124.202 1.00 6.96   ? 393  PHE B CD2 1 
ATOM   6898  C CE1 . PHE B 1 393 ? 120.556 127.383 126.658 1.00 6.96   ? 393  PHE B CE1 1 
ATOM   6899  C CE2 . PHE B 1 393 ? 120.443 127.465 124.284 1.00 6.96   ? 393  PHE B CE2 1 
ATOM   6900  C CZ  . PHE B 1 393 ? 119.962 127.843 125.514 1.00 6.96   ? 393  PHE B CZ  1 
ATOM   6901  N N   . THR B 1 394 ? 126.599 124.545 125.231 1.00 6.11   ? 394  THR B N   1 
ATOM   6902  C CA  . THR B 1 394 ? 127.741 123.735 125.635 1.00 6.11   ? 394  THR B CA  1 
ATOM   6903  C C   . THR B 1 394 ? 128.514 124.420 126.748 1.00 6.11   ? 394  THR B C   1 
ATOM   6904  O O   . THR B 1 394 ? 128.806 123.810 127.778 1.00 6.11   ? 394  THR B O   1 
ATOM   6905  C CB  . THR B 1 394 ? 128.655 123.474 124.442 1.00 6.11   ? 394  THR B CB  1 
ATOM   6906  O OG1 . THR B 1 394 ? 128.001 122.595 123.528 1.00 6.11   ? 394  THR B OG1 1 
ATOM   6907  C CG2 . THR B 1 394 ? 129.957 122.853 124.878 1.00 6.11   ? 394  THR B CG2 1 
ATOM   6908  N N   . GLY B 1 395 ? 128.837 125.697 126.570 1.00 6.16   ? 395  GLY B N   1 
ATOM   6909  C CA  . GLY B 1 395 ? 129.601 126.396 127.583 1.00 6.16   ? 395  GLY B CA  1 
ATOM   6910  C C   . GLY B 1 395 ? 128.800 126.729 128.820 1.00 6.16   ? 395  GLY B C   1 
ATOM   6911  O O   . GLY B 1 395 ? 129.362 126.851 129.908 1.00 6.16   ? 395  GLY B O   1 
ATOM   6912  N N   . CYS B 1 396 ? 127.486 126.888 128.679 1.00 7.82   ? 396  CYS B N   1 
ATOM   6913  C CA  . CYS B 1 396 ? 126.658 127.178 129.839 1.00 7.82   ? 396  CYS B CA  1 
ATOM   6914  C C   . CYS B 1 396 ? 126.491 125.955 130.727 1.00 7.82   ? 396  CYS B C   1 
ATOM   6915  O O   . CYS B 1 396 ? 126.448 126.096 131.950 1.00 7.82   ? 396  CYS B O   1 
ATOM   6916  C CB  . CYS B 1 396 ? 125.300 127.708 129.389 1.00 7.82   ? 396  CYS B CB  1 
ATOM   6917  S SG  . CYS B 1 396 ? 124.089 127.906 130.685 1.00 7.82   ? 396  CYS B SG  1 
ATOM   6918  N N   . PHE B 1 397 ? 126.433 124.762 130.138 1.00 7.91   ? 397  PHE B N   1 
ATOM   6919  C CA  . PHE B 1 397 ? 126.432 123.505 130.874 1.00 7.91   ? 397  PHE B CA  1 
ATOM   6920  C C   . PHE B 1 397 ? 127.764 123.207 131.543 1.00 7.91   ? 397  PHE B C   1 
ATOM   6921  O O   . PHE B 1 397 ? 127.779 122.764 132.692 1.00 7.91   ? 397  PHE B O   1 
ATOM   6922  C CB  . PHE B 1 397 ? 126.039 122.360 129.938 1.00 7.91   ? 397  PHE B CB  1 
ATOM   6923  C CG  . PHE B 1 397 ? 126.468 121.012 130.417 1.00 7.91   ? 397  PHE B CG  1 
ATOM   6924  C CD1 . PHE B 1 397 ? 125.916 120.434 131.546 1.00 7.91   ? 397  PHE B CD1 1 
ATOM   6925  C CD2 . PHE B 1 397 ? 127.417 120.299 129.704 1.00 7.91   ? 397  PHE B CD2 1 
ATOM   6926  C CE1 . PHE B 1 397 ? 126.344 119.202 131.984 1.00 7.91   ? 397  PHE B CE1 1 
ATOM   6927  C CE2 . PHE B 1 397 ? 127.834 119.069 130.132 1.00 7.91   ? 397  PHE B CE2 1 
ATOM   6928  C CZ  . PHE B 1 397 ? 127.298 118.520 131.272 1.00 7.91   ? 397  PHE B CZ  1 
ATOM   6929  N N   . VAL B 1 398 ? 128.880 123.429 130.851 1.00 7.25   ? 398  VAL B N   1 
ATOM   6930  C CA  . VAL B 1 398 ? 130.189 123.117 131.415 1.00 7.25   ? 398  VAL B CA  1 
ATOM   6931  C C   . VAL B 1 398 ? 130.518 124.041 132.583 1.00 7.25   ? 398  VAL B C   1 
ATOM   6932  O O   . VAL B 1 398 ? 131.005 123.585 133.622 1.00 7.25   ? 398  VAL B O   1 
ATOM   6933  C CB  . VAL B 1 398 ? 131.255 123.178 130.307 1.00 7.25   ? 398  VAL B CB  1 
ATOM   6934  C CG1 . VAL B 1 398 ? 132.645 123.162 130.876 1.00 7.25   ? 398  VAL B CG1 1 
ATOM   6935  C CG2 . VAL B 1 398 ? 131.086 122.018 129.370 1.00 7.25   ? 398  VAL B CG2 1 
ATOM   6936  N N   . ALA B 1 399 ? 130.199 125.328 132.474 1.00 7.47   ? 399  ALA B N   1 
ATOM   6937  C CA  . ALA B 1 399 ? 130.488 126.263 133.552 1.00 7.47   ? 399  ALA B CA  1 
ATOM   6938  C C   . ALA B 1 399 ? 129.522 126.157 134.721 1.00 7.47   ? 399  ALA B C   1 
ATOM   6939  O O   . ALA B 1 399 ? 129.896 126.494 135.847 1.00 7.47   ? 399  ALA B O   1 
ATOM   6940  C CB  . ALA B 1 399 ? 130.476 127.690 133.022 1.00 7.47   ? 399  ALA B CB  1 
ATOM   6941  N N   . LEU B 1 400 ? 128.287 125.712 134.488 1.00 11.21  ? 400  LEU B N   1 
ATOM   6942  C CA  . LEU B 1 400 ? 127.377 125.399 135.584 1.00 11.21  ? 400  LEU B CA  1 
ATOM   6943  C C   . LEU B 1 400 ? 127.715 124.082 136.268 1.00 11.21  ? 400  LEU B C   1 
ATOM   6944  O O   . LEU B 1 400 ? 127.516 123.962 137.480 1.00 11.21  ? 400  LEU B O   1 
ATOM   6945  C CB  . LEU B 1 400 ? 125.941 125.353 135.082 1.00 11.21  ? 400  LEU B CB  1 
ATOM   6946  C CG  . LEU B 1 400 ? 125.240 126.697 135.152 1.00 11.21  ? 400  LEU B CG  1 
ATOM   6947  C CD1 . LEU B 1 400 ? 124.060 126.751 134.221 1.00 11.21  ? 400  LEU B CD1 1 
ATOM   6948  C CD2 . LEU B 1 400 ? 124.801 126.927 136.565 1.00 11.21  ? 400  LEU B CD2 1 
ATOM   6949  N N   . LEU B 1 401 ? 128.205 123.095 135.518 1.00 17.09  ? 401  LEU B N   1 
ATOM   6950  C CA  . LEU B 1 401 ? 128.801 121.913 136.123 1.00 17.09  ? 401  LEU B CA  1 
ATOM   6951  C C   . LEU B 1 401 ? 130.064 122.249 136.896 1.00 17.09  ? 401  LEU B C   1 
ATOM   6952  O O   . LEU B 1 401 ? 130.206 121.819 138.041 1.00 17.09  ? 401  LEU B O   1 
ATOM   6953  C CB  . LEU B 1 401 ? 129.129 120.874 135.054 1.00 17.09  ? 401  LEU B CB  1 
ATOM   6954  C CG  . LEU B 1 401 ? 130.035 119.727 135.497 1.00 17.09  ? 401  LEU B CG  1 
ATOM   6955  C CD1 . LEU B 1 401 ? 129.269 118.776 136.382 1.00 17.09  ? 401  LEU B CD1 1 
ATOM   6956  C CD2 . LEU B 1 401 ? 130.646 119.008 134.311 1.00 17.09  ? 401  LEU B CD2 1 
ATOM   6957  N N   . ALA B 1 402 ? 130.984 123.016 136.310 1.00 21.98  ? 402  ALA B N   1 
ATOM   6958  C CA  . ALA B 1 402 ? 132.216 123.361 137.005 1.00 21.98  ? 402  ALA B CA  1 
ATOM   6959  C C   . ALA B 1 402 ? 131.986 124.299 138.180 1.00 21.98  ? 402  ALA B C   1 
ATOM   6960  O O   . ALA B 1 402 ? 132.837 124.373 139.070 1.00 21.98  ? 402  ALA B O   1 
ATOM   6961  C CB  . ALA B 1 402 ? 133.218 123.985 136.038 1.00 21.98  ? 402  ALA B CB  1 
ATOM   6962  N N   . GLY B 1 403 ? 130.857 124.995 138.214 1.00 26.18  ? 403  GLY B N   1 
ATOM   6963  C CA  . GLY B 1 403 ? 130.447 125.705 139.404 1.00 26.18  ? 403  GLY B CA  1 
ATOM   6964  C C   . GLY B 1 403 ? 129.493 124.869 140.225 1.00 26.18  ? 403  GLY B C   1 
ATOM   6965  O O   . GLY B 1 403 ? 128.531 125.390 140.785 1.00 26.18  ? 403  GLY B O   1 
ATOM   6966  N N   . TYR B 1 404 ? 129.723 123.557 140.246 1.00 26.50  ? 404  TYR B N   1 
ATOM   6967  C CA  . TYR B 1 404 ? 128.994 122.616 141.085 1.00 26.50  ? 404  TYR B CA  1 
ATOM   6968  C C   . TYR B 1 404 ? 129.985 121.623 141.671 1.00 26.50  ? 404  TYR B C   1 
ATOM   6969  O O   . TYR B 1 404 ? 129.709 120.993 142.690 1.00 26.50  ? 404  TYR B O   1 
ATOM   6970  C CB  . TYR B 1 404 ? 127.897 121.920 140.277 1.00 26.50  ? 404  TYR B CB  1 
ATOM   6971  C CG  . TYR B 1 404 ? 127.081 120.885 141.007 1.00 26.50  ? 404  TYR B CG  1 
ATOM   6972  C CD1 . TYR B 1 404 ? 127.439 119.543 140.977 1.00 26.50  ? 404  TYR B CD1 1 
ATOM   6973  C CD2 . TYR B 1 404 ? 125.931 121.238 141.687 1.00 26.50  ? 404  TYR B CD2 1 
ATOM   6974  C CE1 . TYR B 1 404 ? 126.693 118.592 141.632 1.00 26.50  ? 404  TYR B CE1 1 
ATOM   6975  C CE2 . TYR B 1 404 ? 125.177 120.291 142.345 1.00 26.50  ? 404  TYR B CE2 1 
ATOM   6976  C CZ  . TYR B 1 404 ? 125.562 118.972 142.310 1.00 26.50  ? 404  TYR B CZ  1 
ATOM   6977  O OH  . TYR B 1 404 ? 124.810 118.028 142.963 1.00 26.50  ? 404  TYR B OH  1 
ATOM   6978  N N   . ILE B 1 405 ? 131.148 121.474 141.033 1.00 36.31  ? 405  ILE B N   1 
ATOM   6979  C CA  . ILE B 1 405 ? 132.242 120.694 141.601 1.00 36.31  ? 405  ILE B CA  1 
ATOM   6980  C C   . ILE B 1 405 ? 133.267 121.586 142.295 1.00 36.31  ? 405  ILE B C   1 
ATOM   6981  O O   . ILE B 1 405 ? 134.325 121.103 142.727 1.00 36.31  ? 405  ILE B O   1 
ATOM   6982  C CB  . ILE B 1 405 ? 132.914 119.818 140.524 1.00 36.31  ? 405  ILE B CB  1 
ATOM   6983  C CG1 . ILE B 1 405 ? 131.906 119.419 139.463 1.00 36.31  ? 405  ILE B CG1 1 
ATOM   6984  C CG2 . ILE B 1 405 ? 133.392 118.500 141.108 1.00 36.31  ? 405  ILE B CG2 1 
ATOM   6985  C CD1 . ILE B 1 405 ? 132.543 118.806 138.247 1.00 36.31  ? 405  ILE B CD1 1 
ATOM   6986  N N   . ILE B 1 406 ? 132.985 122.885 142.409 1.00 50.32  ? 406  ILE B N   1 
ATOM   6987  C CA  . ILE B 1 406 ? 133.739 123.786 143.268 1.00 50.32  ? 406  ILE B CA  1 
ATOM   6988  C C   . ILE B 1 406 ? 132.944 124.165 144.510 1.00 50.32  ? 406  ILE B C   1 
ATOM   6989  O O   . ILE B 1 406 ? 133.460 124.084 145.630 1.00 50.32  ? 406  ILE B O   1 
ATOM   6990  C CB  . ILE B 1 406 ? 134.187 125.051 142.498 1.00 50.32  ? 406  ILE B CB  1 
ATOM   6991  C CG1 . ILE B 1 406 ? 135.341 124.716 141.557 1.00 50.32  ? 406  ILE B CG1 1 
ATOM   6992  C CG2 . ILE B 1 406 ? 134.620 126.163 143.438 1.00 50.32  ? 406  ILE B CG2 1 
ATOM   6993  C CD1 . ILE B 1 406 ? 136.592 124.262 142.269 1.00 50.32  ? 406  ILE B CD1 1 
ATOM   6994  N N   . VAL B 1 407 ? 131.672 124.528 144.342 1.00 52.88  ? 407  VAL B N   1 
ATOM   6995  C CA  . VAL B 1 407 ? 130.870 124.945 145.484 1.00 52.88  ? 407  VAL B CA  1 
ATOM   6996  C C   . VAL B 1 407 ? 130.511 123.752 146.371 1.00 52.88  ? 407  VAL B C   1 
ATOM   6997  O O   . VAL B 1 407 ? 130.569 123.854 147.599 1.00 52.88  ? 407  VAL B O   1 
ATOM   6998  C CB  . VAL B 1 407 ? 129.633 125.736 145.006 1.00 52.88  ? 407  VAL B CB  1 
ATOM   6999  C CG1 . VAL B 1 407 ? 128.840 124.970 143.990 1.00 52.88  ? 407  VAL B CG1 1 
ATOM   7000  C CG2 . VAL B 1 407 ? 128.744 126.141 146.168 1.00 52.88  ? 407  VAL B CG2 1 
ATOM   7001  N N   . ALA B 1 408 ? 130.207 122.586 145.787 1.00 56.47  ? 408  ALA B N   1 
ATOM   7002  C CA  . ALA B 1 408 ? 129.897 121.426 146.617 1.00 56.47  ? 408  ALA B CA  1 
ATOM   7003  C C   . ALA B 1 408 ? 131.150 120.842 147.243 1.00 56.47  ? 408  ALA B C   1 
ATOM   7004  O O   . ALA B 1 408 ? 131.067 120.181 148.283 1.00 56.47  ? 408  ALA B O   1 
ATOM   7005  C CB  . ALA B 1 408 ? 129.177 120.351 145.814 1.00 56.47  ? 408  ALA B CB  1 
ATOM   7006  N N   . HIS B 1 409 ? 132.304 121.058 146.614 1.00 56.07  ? 409  HIS B N   1 
ATOM   7007  C CA  . HIS B 1 409 ? 133.577 120.759 147.257 1.00 56.07  ? 409  HIS B CA  1 
ATOM   7008  C C   . HIS B 1 409 ? 133.760 121.611 148.506 1.00 56.07  ? 409  HIS B C   1 
ATOM   7009  O O   . HIS B 1 409 ? 134.199 121.124 149.553 1.00 56.07  ? 409  HIS B O   1 
ATOM   7010  C CB  . HIS B 1 409 ? 134.713 120.998 146.263 1.00 56.07  ? 409  HIS B CB  1 
ATOM   7011  C CG  . HIS B 1 409 ? 135.932 120.169 146.515 1.00 56.07  ? 409  HIS B CG  1 
ATOM   7012  N ND1 . HIS B 1 409 ? 136.743 120.352 147.614 1.00 56.07  ? 409  HIS B ND1 1 
ATOM   7013  C CD2 . HIS B 1 409 ? 136.490 119.166 145.799 1.00 56.07  ? 409  HIS B CD2 1 
ATOM   7014  C CE1 . HIS B 1 409 ? 137.743 119.490 147.568 1.00 56.07  ? 409  HIS B CE1 1 
ATOM   7015  N NE2 . HIS B 1 409 ? 137.613 118.759 146.477 1.00 56.07  ? 409  HIS B NE2 1 
ATOM   7016  N N   . LEU B 1 410 ? 133.419 122.889 148.410 1.00 57.33  ? 410  LEU B N   1 
ATOM   7017  C CA  . LEU B 1 410 ? 133.520 123.829 149.525 1.00 57.33  ? 410  LEU B CA  1 
ATOM   7018  C C   . LEU B 1 410 ? 132.178 123.951 150.251 1.00 57.33  ? 410  LEU B C   1 
ATOM   7019  O O   . LEU B 1 410 ? 131.627 125.021 150.477 1.00 57.33  ? 410  LEU B O   1 
ATOM   7020  C CB  . LEU B 1 410 ? 134.039 125.164 148.988 1.00 57.33  ? 410  LEU B CB  1 
ATOM   7021  C CG  . LEU B 1 410 ? 134.436 126.453 149.706 1.00 57.33  ? 410  LEU B CG  1 
ATOM   7022  C CD1 . LEU B 1 410 ? 135.674 126.921 148.997 1.00 57.33  ? 410  LEU B CD1 1 
ATOM   7023  C CD2 . LEU B 1 410 ? 133.389 127.543 149.600 1.00 57.33  ? 410  LEU B CD2 1 
ATOM   7024  N N   . THR B 1 411 ? 131.612 122.805 150.610 1.00 55.84  ? 411  THR B N   1 
ATOM   7025  C CA  . THR B 1 411 ? 130.393 122.764 151.405 1.00 55.84  ? 411  THR B CA  1 
ATOM   7026  C C   . THR B 1 411 ? 130.464 121.655 152.446 1.00 55.84  ? 411  THR B C   1 
ATOM   7027  O O   . THR B 1 411 ? 129.651 121.641 153.377 1.00 55.84  ? 411  THR B O   1 
ATOM   7028  C CB  . THR B 1 411 ? 129.154 122.571 150.481 1.00 55.84  ? 411  THR B CB  1 
ATOM   7029  O OG1 . THR B 1 411 ? 129.261 123.435 149.350 1.00 55.84  ? 411  THR B OG1 1 
ATOM   7030  C CG2 . THR B 1 411 ? 127.833 122.923 151.155 1.00 55.84  ? 411  THR B CG2 1 
ATOM   7031  N N   . GLY B 1 412 ? 131.480 120.801 152.403 1.00 67.29  ? 412  GLY B N   1 
ATOM   7032  C CA  . GLY B 1 412 ? 131.281 119.525 153.045 1.00 67.29  ? 412  GLY B CA  1 
ATOM   7033  C C   . GLY B 1 412 ? 130.609 118.207 152.731 1.00 67.29  ? 412  GLY B C   1 
ATOM   7034  O O   . GLY B 1 412 ? 130.711 117.250 153.505 1.00 67.29  ? 412  GLY B O   1 
ATOM   7035  N N   . MET B 1 413 ? 129.933 118.160 151.580 1.00 74.13  ? 413  MET B N   1 
ATOM   7036  C CA  . MET B 1 413 ? 128.875 117.241 151.155 1.00 74.13  ? 413  MET B CA  1 
ATOM   7037  C C   . MET B 1 413 ? 129.534 116.419 150.042 1.00 74.13  ? 413  MET B C   1 
ATOM   7038  O O   . MET B 1 413 ? 129.104 115.285 149.800 1.00 74.13  ? 413  MET B O   1 
ATOM   7039  C CB  . MET B 1 413 ? 127.550 117.799 150.624 1.00 74.13  ? 413  MET B CB  1 
ATOM   7040  C CG  . MET B 1 413 ? 127.022 118.975 151.447 1.00 74.13  ? 413  MET B CG  1 
ATOM   7041  S SD  . MET B 1 413 ? 125.703 119.954 150.695 1.00 74.13  ? 413  MET B SD  1 
ATOM   7042  C CE  . MET B 1 413 ? 124.343 118.795 150.687 1.00 74.13  ? 413  MET B CE  1 
ATOM   7043  N N   . TYR B 1 414 ? 130.536 116.984 149.350 1.00 75.21  ? 414  TYR B N   1 
ATOM   7044  C CA  . TYR B 1 414 ? 131.224 116.306 148.245 1.00 75.21  ? 414  TYR B CA  1 
ATOM   7045  C C   . TYR B 1 414 ? 131.838 114.967 148.656 1.00 75.21  ? 414  TYR B C   1 
ATOM   7046  O O   . TYR B 1 414 ? 131.888 114.028 147.853 1.00 75.21  ? 414  TYR B O   1 
ATOM   7047  C CB  . TYR B 1 414 ? 132.303 117.233 147.678 1.00 75.21  ? 414  TYR B CB  1 
ATOM   7048  C CG  . TYR B 1 414 ? 133.352 116.573 146.806 1.00 75.21  ? 414  TYR B CG  1 
ATOM   7049  C CD1 . TYR B 1 414 ? 134.669 116.457 147.239 1.00 75.21  ? 414  TYR B CD1 1 
ATOM   7050  C CD2 . TYR B 1 414 ? 133.032 116.090 145.540 1.00 75.21  ? 414  TYR B CD2 1 
ATOM   7051  C CE1 . TYR B 1 414 ? 135.636 115.865 146.445 1.00 75.21  ? 414  TYR B CE1 1 
ATOM   7052  C CE2 . TYR B 1 414 ? 133.994 115.497 144.736 1.00 75.21  ? 414  TYR B CE2 1 
ATOM   7053  C CZ  . TYR B 1 414 ? 135.293 115.387 145.194 1.00 75.21  ? 414  TYR B CZ  1 
ATOM   7054  O OH  . TYR B 1 414 ? 136.252 114.797 144.400 1.00 75.21  ? 414  TYR B OH  1 
ATOM   7055  N N   . ARG B 1 415 ? 132.305 114.854 149.896 1.00 75.72  ? 415  ARG B N   1 
ATOM   7056  C CA  . ARG B 1 415 ? 132.716 113.570 150.447 1.00 75.72  ? 415  ARG B CA  1 
ATOM   7057  C C   . ARG B 1 415 ? 131.755 113.062 151.509 1.00 75.72  ? 415  ARG B C   1 
ATOM   7058  O O   . ARG B 1 415 ? 132.063 112.061 152.167 1.00 75.72  ? 415  ARG B O   1 
ATOM   7059  C CB  . ARG B 1 415 ? 134.126 113.657 151.040 1.00 75.72  ? 415  ARG B CB  1 
ATOM   7060  C CG  . ARG B 1 415 ? 135.246 113.789 150.023 1.00 75.72  ? 415  ARG B CG  1 
ATOM   7061  C CD  . ARG B 1 415 ? 136.582 113.992 150.728 1.00 75.72  ? 415  ARG B CD  1 
ATOM   7062  N NE  . ARG B 1 415 ? 137.703 114.082 149.799 1.00 75.72  ? 415  ARG B NE  1 
ATOM   7063  C CZ  . ARG B 1 415 ? 138.069 115.197 149.177 1.00 75.72  ? 415  ARG B CZ  1 
ATOM   7064  N NH1 . ARG B 1 415 ? 139.105 115.185 148.352 1.00 75.72  ? 415  ARG B NH1 1 
ATOM   7065  N NH2 . ARG B 1 415 ? 137.401 116.325 149.379 1.00 75.72  ? 415  ARG B NH2 1 
ATOM   7066  N N   . GLN B 1 416 ? 130.604 113.725 151.673 1.00 69.21  ? 416  GLN B N   1 
ATOM   7067  C CA  . GLN B 1 416 ? 129.620 113.467 152.732 1.00 69.21  ? 416  GLN B CA  1 
ATOM   7068  C C   . GLN B 1 416 ? 130.256 113.480 154.123 1.00 69.21  ? 416  GLN B C   1 
ATOM   7069  O O   . GLN B 1 416 ? 130.023 112.602 154.956 1.00 69.21  ? 416  GLN B O   1 
ATOM   7070  C CB  . GLN B 1 416 ? 128.854 112.166 152.481 1.00 69.21  ? 416  GLN B CB  1 
ATOM   7071  C CG  . GLN B 1 416 ? 127.609 112.378 151.649 1.00 69.21  ? 416  GLN B CG  1 
ATOM   7072  C CD  . GLN B 1 416 ? 126.564 113.207 152.371 1.00 69.21  ? 416  GLN B CD  1 
ATOM   7073  O OE1 . GLN B 1 416 ? 126.342 113.043 153.569 1.00 69.21  ? 416  GLN B OE1 1 
ATOM   7074  N NE2 . GLN B 1 416 ? 125.931 114.120 151.646 1.00 69.21  ? 416  GLN B NE2 1 
ATOM   7075  N N   . HIS B 1 417 ? 131.078 114.498 154.365 1.00 72.75  ? 417  HIS B N   1 
ATOM   7076  C CA  . HIS B 1 417 ? 131.633 114.784 155.686 1.00 72.75  ? 417  HIS B CA  1 
ATOM   7077  C C   . HIS B 1 417 ? 130.942 115.986 156.317 1.00 72.75  ? 417  HIS B C   1 
ATOM   7078  O O   . HIS B 1 417 ? 131.570 116.831 156.962 1.00 72.75  ? 417  HIS B O   1 
ATOM   7079  C CB  . HIS B 1 417 ? 133.146 114.976 155.609 1.00 72.75  ? 417  HIS B CB  1 
ATOM   7080  C CG  . HIS B 1 417 ? 133.583 116.119 154.747 1.00 72.75  ? 417  HIS B CG  1 
ATOM   7081  N ND1 . HIS B 1 417 ? 133.825 117.378 155.250 1.00 72.75  ? 417  HIS B ND1 1 
ATOM   7082  C CD2 . HIS B 1 417 ? 133.841 116.189 153.420 1.00 72.75  ? 417  HIS B CD2 1 
ATOM   7083  C CE1 . HIS B 1 417 ? 134.213 118.175 154.271 1.00 72.75  ? 417  HIS B CE1 1 
ATOM   7084  N NE2 . HIS B 1 417 ? 134.223 117.480 153.148 1.00 72.75  ? 417  HIS B NE2 1 
ATOM   7085  N N   . SER B 1 418 ? 129.628 116.066 156.146 1.00 67.88  ? 418  SER B N   1 
ATOM   7086  C CA  . SER B 1 418 ? 128.862 117.274 156.409 1.00 67.88  ? 418  SER B CA  1 
ATOM   7087  C C   . SER B 1 418 ? 127.507 116.878 156.981 1.00 67.88  ? 418  SER B C   1 
ATOM   7088  O O   . SER B 1 418 ? 127.359 115.801 157.568 1.00 67.88  ? 418  SER B O   1 
ATOM   7089  C CB  . SER B 1 418 ? 128.700 118.100 155.127 1.00 67.88  ? 418  SER B CB  1 
ATOM   7090  O OG  . SER B 1 418 ? 127.548 117.683 154.420 1.00 67.88  ? 418  SER B OG  1 
ATOM   7091  N N   . ALA B 1 419 ? 126.518 117.755 156.797 1.00 62.24  ? 419  ALA B N   1 
ATOM   7092  C CA  . ALA B 1 419 ? 125.150 117.591 157.280 1.00 62.24  ? 419  ALA B CA  1 
ATOM   7093  C C   . ALA B 1 419 ? 124.382 116.504 156.528 1.00 62.24  ? 419  ALA B C   1 
ATOM   7094  O O   . ALA B 1 419 ? 124.991 115.681 155.835 1.00 62.24  ? 419  ALA B O   1 
ATOM   7095  C CB  . ALA B 1 419 ? 124.400 118.922 157.189 1.00 62.24  ? 419  ALA B CB  1 
ATOM   7096  N N   . ASN B 1 420 ? 123.052 116.492 156.719 1.00 58.26  ? 420  ASN B N   1 
ATOM   7097  C CA  . ASN B 1 420 ? 122.127 115.425 156.317 1.00 58.26  ? 420  ASN B CA  1 
ATOM   7098  C C   . ASN B 1 420 ? 122.337 114.926 154.891 1.00 58.26  ? 420  ASN B C   1 
ATOM   7099  O O   . ASN B 1 420 ? 122.694 115.689 153.990 1.00 58.26  ? 420  ASN B O   1 
ATOM   7100  C CB  . ASN B 1 420 ? 120.685 115.921 156.471 1.00 58.26  ? 420  ASN B CB  1 
ATOM   7101  C CG  . ASN B 1 420 ? 120.496 117.349 155.979 1.00 58.26  ? 420  ASN B CG  1 
ATOM   7102  O OD1 . ASN B 1 420 ? 120.858 117.694 154.853 1.00 58.26  ? 420  ASN B OD1 1 
ATOM   7103  N ND2 . ASN B 1 420 ? 119.921 118.189 156.830 1.00 58.26  ? 420  ASN B ND2 1 
ATOM   7104  N N   . THR B 1 421 ? 122.117 113.624 154.704 1.00 55.61  ? 421  THR B N   1 
ATOM   7105  C CA  . THR B 1 421 ? 122.438 112.923 153.469 1.00 55.61  ? 421  THR B CA  1 
ATOM   7106  C C   . THR B 1 421 ? 121.271 112.978 152.462 1.00 55.61  ? 421  THR B C   1 
ATOM   7107  O O   . THR B 1 421 ? 121.081 112.079 151.636 1.00 55.61  ? 421  THR B O   1 
ATOM   7108  C CB  . THR B 1 421 ? 122.851 111.481 153.802 1.00 55.61  ? 421  THR B CB  1 
ATOM   7109  O OG1 . THR B 1 421 ? 123.632 111.502 155.000 1.00 55.61  ? 421  THR B OG1 1 
ATOM   7110  C CG2 . THR B 1 421 ? 123.782 110.890 152.731 1.00 55.61  ? 421  THR B CG2 1 
ATOM   7111  N N   . PHE B 1 422 ? 120.460 114.032 152.507 1.00 60.10  ? 422  PHE B N   1 
ATOM   7112  C CA  . PHE B 1 422 ? 119.458 114.260 151.464 1.00 60.10  ? 422  PHE B CA  1 
ATOM   7113  C C   . PHE B 1 422 ? 120.057 114.980 150.257 1.00 60.10  ? 422  PHE B C   1 
ATOM   7114  O O   . PHE B 1 422 ? 119.454 115.891 149.693 1.00 60.10  ? 422  PHE B O   1 
ATOM   7115  C CB  . PHE B 1 422 ? 118.297 115.061 152.034 1.00 60.10  ? 422  PHE B CB  1 
ATOM   7116  C CG  . PHE B 1 422 ? 117.406 114.280 152.940 1.00 60.10  ? 422  PHE B CG  1 
ATOM   7117  C CD1 . PHE B 1 422 ? 116.595 113.275 152.443 1.00 60.10  ? 422  PHE B CD1 1 
ATOM   7118  C CD2 . PHE B 1 422 ? 117.384 114.546 154.300 1.00 60.10  ? 422  PHE B CD2 1 
ATOM   7119  C CE1 . PHE B 1 422 ? 115.763 112.557 153.280 1.00 60.10  ? 422  PHE B CE1 1 
ATOM   7120  C CE2 . PHE B 1 422 ? 116.565 113.825 155.149 1.00 60.10  ? 422  PHE B CE2 1 
ATOM   7121  C CZ  . PHE B 1 422 ? 115.754 112.827 154.638 1.00 60.10  ? 422  PHE B CZ  1 
ATOM   7122  N N   . TYR B 1 423 ? 121.244 114.548 149.835 1.00 55.69  ? 423  TYR B N   1 
ATOM   7123  C CA  . TYR B 1 423 ? 121.893 115.023 148.627 1.00 55.69  ? 423  TYR B CA  1 
ATOM   7124  C C   . TYR B 1 423 ? 122.111 113.822 147.723 1.00 55.69  ? 423  TYR B C   1 
ATOM   7125  O O   . TYR B 1 423 ? 121.634 113.794 146.586 1.00 55.69  ? 423  TYR B O   1 
ATOM   7126  C CB  . TYR B 1 423 ? 123.204 115.740 148.986 1.00 55.69  ? 423  TYR B CB  1 
ATOM   7127  C CG  . TYR B 1 423 ? 124.263 115.847 147.901 1.00 55.69  ? 423  TYR B CG  1 
ATOM   7128  C CD1 . TYR B 1 423 ? 125.318 114.939 147.835 1.00 55.69  ? 423  TYR B CD1 1 
ATOM   7129  C CD2 . TYR B 1 423 ? 124.236 116.879 146.972 1.00 55.69  ? 423  TYR B CD2 1 
ATOM   7130  C CE1 . TYR B 1 423 ? 126.294 115.040 146.857 1.00 55.69  ? 423  TYR B CE1 1 
ATOM   7131  C CE2 . TYR B 1 423 ? 125.210 116.987 145.991 1.00 55.69  ? 423  TYR B CE2 1 
ATOM   7132  C CZ  . TYR B 1 423 ? 126.235 116.064 145.940 1.00 55.69  ? 423  TYR B CZ  1 
ATOM   7133  O OH  . TYR B 1 423 ? 127.209 116.159 144.971 1.00 55.69  ? 423  TYR B OH  1 
ATOM   7134  N N   . MET B 1 424 ? 122.774 112.796 148.253 1.00 51.70  ? 424  MET B N   1 
ATOM   7135  C CA  . MET B 1 424 ? 123.156 111.626 147.476 1.00 51.70  ? 424  MET B CA  1 
ATOM   7136  C C   . MET B 1 424 ? 122.090 110.543 147.474 1.00 51.70  ? 424  MET B C   1 
ATOM   7137  O O   . MET B 1 424 ? 122.366 109.419 147.045 1.00 51.70  ? 424  MET B O   1 
ATOM   7138  C CB  . MET B 1 424 ? 124.477 111.054 147.990 1.00 51.70  ? 424  MET B CB  1 
ATOM   7139  C CG  . MET B 1 424 ? 125.398 110.583 146.892 1.00 51.70  ? 424  MET B CG  1 
ATOM   7140  S SD  . MET B 1 424 ? 127.035 110.201 147.505 1.00 51.70  ? 424  MET B SD  1 
ATOM   7141  C CE  . MET B 1 424 ? 127.564 111.841 147.966 1.00 51.70  ? 424  MET B CE  1 
ATOM   7142  N N   . GLU B 1 425 ? 120.892 110.844 147.966 1.00 46.86  ? 425  GLU B N   1 
ATOM   7143  C CA  . GLU B 1 425 ? 119.743 109.967 147.821 1.00 46.86  ? 425  GLU B CA  1 
ATOM   7144  C C   . GLU B 1 425 ? 118.515 110.708 147.322 1.00 46.86  ? 425  GLU B C   1 
ATOM   7145  O O   . GLU B 1 425 ? 117.485 110.072 147.077 1.00 46.86  ? 425  GLU B O   1 
ATOM   7146  C CB  . GLU B 1 425 ? 119.417 109.260 149.147 1.00 46.86  ? 425  GLU B CB  1 
ATOM   7147  C CG  . GLU B 1 425 ? 120.552 108.411 149.703 1.00 46.86  ? 425  GLU B CG  1 
ATOM   7148  C CD  . GLU B 1 425 ? 120.504 108.260 151.205 1.00 46.86  ? 425  GLU B CD  1 
ATOM   7149  O OE1 . GLU B 1 425 ? 120.450 109.293 151.900 1.00 46.86  ? 425  GLU B OE1 1 
ATOM   7150  O OE2 . GLU B 1 425 ? 120.522 107.108 151.689 1.00 46.86  ? 425  GLU B OE2 1 
ATOM   7151  N N   . THR B 1 426 ? 118.592 112.027 147.162 1.00 44.54  ? 426  THR B N   1 
ATOM   7152  C CA  . THR B 1 426 ? 117.479 112.816 146.653 1.00 44.54  ? 426  THR B CA  1 
ATOM   7153  C C   . THR B 1 426 ? 117.709 113.233 145.209 1.00 44.54  ? 426  THR B C   1 
ATOM   7154  O O   . THR B 1 426 ? 116.873 112.962 144.343 1.00 44.54  ? 426  THR B O   1 
ATOM   7155  C CB  . THR B 1 426 ? 117.282 114.058 147.517 1.00 44.54  ? 426  THR B CB  1 
ATOM   7156  O OG1 . THR B 1 426 ? 118.526 114.764 147.610 1.00 44.54  ? 426  THR B OG1 1 
ATOM   7157  C CG2 . THR B 1 426 ? 116.830 113.649 148.891 1.00 44.54  ? 426  THR B CG2 1 
ATOM   7158  N N   . ALA B 1 427 ? 118.910 113.840 145.032 1.00 33.26  ? 427  ALA B N   1 
ATOM   7159  C CA  . ALA B 1 427 ? 119.369 114.357 143.725 1.00 33.26  ? 427  ALA B CA  1 
ATOM   7160  C C   . ALA B 1 427 ? 120.781 113.885 143.381 1.00 33.26  ? 427  ALA B C   1 
ATOM   7161  O O   . ALA B 1 427 ? 121.647 114.753 143.216 1.00 33.26  ? 427  ALA B O   1 
ATOM   7162  C CB  . ALA B 1 427 ? 119.354 115.847 143.695 1.00 33.26  ? 427  ALA B CB  1 
ATOM   7163  N N   . TYR B 1 428 ? 121.059 112.595 143.462 1.00 30.40  ? 428  TYR B N   1 
ATOM   7164  C CA  . TYR B 1 428 ? 122.238 111.977 142.806 1.00 30.40  ? 428  TYR B CA  1 
ATOM   7165  C C   . TYR B 1 428 ? 121.526 110.870 142.022 1.00 30.40  ? 428  TYR B C   1 
ATOM   7166  O O   . TYR B 1 428 ? 122.012 110.469 140.962 1.00 30.40  ? 428  TYR B O   1 
ATOM   7167  C CB  . TYR B 1 428 ? 123.339 111.489 143.737 1.00 30.40  ? 428  TYR B CB  1 
ATOM   7168  C CG  . TYR B 1 428 ? 124.435 110.719 143.049 1.00 30.40  ? 428  TYR B CG  1 
ATOM   7169  C CD1 . TYR B 1 428 ? 124.364 109.344 142.914 1.00 30.40  ? 428  TYR B CD1 1 
ATOM   7170  C CD2 . TYR B 1 428 ? 125.547 111.361 142.541 1.00 30.40  ? 428  TYR B CD2 1 
ATOM   7171  C CE1 . TYR B 1 428 ? 125.371 108.625 142.296 1.00 30.40  ? 428  TYR B CE1 1 
ATOM   7172  C CE2 . TYR B 1 428 ? 126.563 110.659 141.917 1.00 30.40  ? 428  TYR B CE2 1 
ATOM   7173  C CZ  . TYR B 1 428 ? 126.477 109.285 141.793 1.00 30.40  ? 428  TYR B CZ  1 
ATOM   7174  O OH  . TYR B 1 428 ? 127.475 108.581 141.181 1.00 30.40  ? 428  TYR B OH  1 
ATOM   7175  N N   . PRO B 1 429 ? 120.351 110.379 142.473 1.00 20.91  ? 429  PRO B N   1 
ATOM   7176  C CA  . PRO B 1 429 ? 119.542 109.529 141.656 1.00 20.91  ? 429  PRO B CA  1 
ATOM   7177  C C   . PRO B 1 429 ? 118.832 110.328 140.567 1.00 20.91  ? 429  PRO B C   1 
ATOM   7178  O O   . PRO B 1 429 ? 118.013 109.748 139.919 1.00 20.91  ? 429  PRO B O   1 
ATOM   7179  C CB  . PRO B 1 429 ? 118.627 108.790 142.612 1.00 20.91  ? 429  PRO B CB  1 
ATOM   7180  C CG  . PRO B 1 429 ? 118.670 109.612 143.855 1.00 20.91  ? 429  PRO B CG  1 
ATOM   7181  C CD  . PRO B 1 429 ? 120.095 110.102 143.894 1.00 20.91  ? 429  PRO B CD  1 
ATOM   7182  N N   . VAL B 1 430 ? 119.091 111.631 140.446 1.00 18.56  ? 430  VAL B N   1 
ATOM   7183  C CA  . VAL B 1 430 ? 118.592 112.453 139.290 1.00 18.56  ? 430  VAL B CA  1 
ATOM   7184  C C   . VAL B 1 430 ? 119.646 113.203 138.485 1.00 18.56  ? 430  VAL B C   1 
ATOM   7185  O O   . VAL B 1 430 ? 119.272 113.821 137.493 1.00 18.56  ? 430  VAL B O   1 
ATOM   7186  C CB  . VAL B 1 430 ? 117.568 113.472 139.802 1.00 18.56  ? 430  VAL B CB  1 
ATOM   7187  C CG1 . VAL B 1 430 ? 117.063 114.362 138.676 1.00 18.56  ? 430  VAL B CG1 1 
ATOM   7188  C CG2 . VAL B 1 430 ? 116.427 112.840 140.575 1.00 18.56  ? 430  VAL B CG2 1 
ATOM   7189  N N   . LEU B 1 431 ? 120.890 113.193 138.926 1.00 21.65  ? 431  LEU B N   1 
ATOM   7190  C CA  . LEU B 1 431 ? 121.950 113.769 138.088 1.00 21.65  ? 431  LEU B CA  1 
ATOM   7191  C C   . LEU B 1 431 ? 122.654 112.541 137.564 1.00 21.65  ? 431  LEU B C   1 
ATOM   7192  O O   . LEU B 1 431 ? 123.639 112.697 136.858 1.00 21.65  ? 431  LEU B O   1 
ATOM   7193  C CB  . LEU B 1 431 ? 122.852 114.694 138.890 1.00 21.65  ? 431  LEU B CB  1 
ATOM   7194  C CG  . LEU B 1 431 ? 122.611 116.182 138.664 1.00 21.65  ? 431  LEU B CG  1 
ATOM   7195  C CD1 . LEU B 1 431 ? 123.624 117.006 139.436 1.00 21.65  ? 431  LEU B CD1 1 
ATOM   7196  C CD2 . LEU B 1 431 ? 122.675 116.516 137.185 1.00 21.65  ? 431  LEU B CD2 1 
ATOM   7197  N N   . SER B 1 432 ? 122.224 111.365 137.992 1.00 21.03  ? 432  SER B N   1 
ATOM   7198  C CA  . SER B 1 432 ? 122.637 110.116 137.369 1.00 21.03  ? 432  SER B CA  1 
ATOM   7199  C C   . SER B 1 432 ? 121.733 109.766 136.194 1.00 21.03  ? 432  SER B C   1 
ATOM   7200  O O   . SER B 1 432 ? 122.218 109.462 135.105 1.00 21.03  ? 432  SER B O   1 
ATOM   7201  C CB  . SER B 1 432 ? 122.639 108.996 138.405 1.00 21.03  ? 432  SER B CB  1 
ATOM   7202  O OG  . SER B 1 432 ? 122.559 107.722 137.792 1.00 21.03  ? 432  SER B OG  1 
ATOM   7203  N N   . MET B 1 433 ? 120.418 109.847 136.390 1.00 35.55  ? 433  MET B N   1 
ATOM   7204  C CA  . MET B 1 433 ? 119.469 109.505 135.343 1.00 35.55  ? 433  MET B CA  1 
ATOM   7205  C C   . MET B 1 433 ? 119.473 110.515 134.204 1.00 35.55  ? 433  MET B C   1 
ATOM   7206  O O   . MET B 1 433 ? 118.971 110.223 133.116 1.00 35.55  ? 433  MET B O   1 
ATOM   7207  C CB  . MET B 1 433 ? 118.079 109.396 135.942 1.00 35.55  ? 433  MET B CB  1 
ATOM   7208  C CG  . MET B 1 433 ? 117.125 108.600 135.132 1.00 35.55  ? 433  MET B CG  1 
ATOM   7209  S SD  . MET B 1 433 ? 116.019 109.673 134.253 1.00 35.55  ? 433  MET B SD  1 
ATOM   7210  C CE  . MET B 1 433 ? 115.107 110.241 135.650 1.00 35.55  ? 433  MET B CE  1 
ATOM   7211  N N   . PHE B 1 434 ? 120.037 111.693 134.404 1.00 32.32  ? 434  PHE B N   1 
ATOM   7212  C CA  . PHE B 1 434 ? 120.087 112.661 133.325 1.00 32.32  ? 434  PHE B CA  1 
ATOM   7213  C C   . PHE B 1 434 ? 121.463 112.789 132.703 1.00 32.32  ? 434  PHE B C   1 
ATOM   7214  O O   . PHE B 1 434 ? 121.590 113.404 131.645 1.00 32.32  ? 434  PHE B O   1 
ATOM   7215  C CB  . PHE B 1 434 ? 119.623 114.024 133.819 1.00 32.32  ? 434  PHE B CB  1 
ATOM   7216  C CG  . PHE B 1 434 ? 118.146 114.203 133.775 1.00 32.32  ? 434  PHE B CG  1 
ATOM   7217  C CD1 . PHE B 1 434 ? 117.440 113.914 132.625 1.00 32.32  ? 434  PHE B CD1 1 
ATOM   7218  C CD2 . PHE B 1 434 ? 117.466 114.687 134.874 1.00 32.32  ? 434  PHE B CD2 1 
ATOM   7219  C CE1 . PHE B 1 434 ? 116.086 114.085 132.577 1.00 32.32  ? 434  PHE B CE1 1 
ATOM   7220  C CE2 . PHE B 1 434 ? 116.113 114.857 134.834 1.00 32.32  ? 434  PHE B CE2 1 
ATOM   7221  C CZ  . PHE B 1 434 ? 115.422 114.556 133.681 1.00 32.32  ? 434  PHE B CZ  1 
ATOM   7222  N N   . GLY B 1 435 ? 122.488 112.238 133.326 1.00 18.24  ? 435  GLY B N   1 
ATOM   7223  C CA  . GLY B 1 435 ? 123.771 112.184 132.675 1.00 18.24  ? 435  GLY B CA  1 
ATOM   7224  C C   . GLY B 1 435 ? 123.955 110.988 131.795 1.00 18.24  ? 435  GLY B C   1 
ATOM   7225  O O   . GLY B 1 435 ? 124.897 110.954 131.003 1.00 18.24  ? 435  GLY B O   1 
ATOM   7226  N N   . LEU B 1 436 ? 123.073 109.995 131.920 1.00 14.90  ? 436  LEU B N   1 
ATOM   7227  C CA  . LEU B 1 436 ? 123.066 108.798 131.088 1.00 14.90  ? 436  LEU B CA  1 
ATOM   7228  C C   . LEU B 1 436 ? 122.102 108.903 129.922 1.00 14.90  ? 436  LEU B C   1 
ATOM   7229  O O   . LEU B 1 436 ? 122.414 108.433 128.831 1.00 14.90  ? 436  LEU B O   1 
ATOM   7230  C CB  . LEU B 1 436 ? 122.704 107.570 131.920 1.00 14.90  ? 436  LEU B CB  1 
ATOM   7231  C CG  . LEU B 1 436 ? 123.602 107.257 133.107 1.00 14.90  ? 436  LEU B CG  1 
ATOM   7232  C CD1 . LEU B 1 436 ? 123.120 106.028 133.810 1.00 14.90  ? 436  LEU B CD1 1 
ATOM   7233  C CD2 . LEU B 1 436 ? 124.999 107.068 132.642 1.00 14.90  ? 436  LEU B CD2 1 
ATOM   7234  N N   . LEU B 1 437 ? 120.936 109.508 130.129 1.00 27.16  ? 437  LEU B N   1 
ATOM   7235  C CA  . LEU B 1 437 ? 119.992 109.694 129.038 1.00 27.16  ? 437  LEU B CA  1 
ATOM   7236  C C   . LEU B 1 437 ? 120.469 110.743 128.040 1.00 27.16  ? 437  LEU B C   1 
ATOM   7237  O O   . LEU B 1 437 ? 120.226 110.606 126.840 1.00 27.16  ? 437  LEU B O   1 
ATOM   7238  C CB  . LEU B 1 437 ? 118.636 110.063 129.611 1.00 27.16  ? 437  LEU B CB  1 
ATOM   7239  C CG  . LEU B 1 437 ? 117.520 110.380 128.631 1.00 27.16  ? 437  LEU B CG  1 
ATOM   7240  C CD1 . LEU B 1 437 ? 117.292 109.240 127.673 1.00 27.16  ? 437  LEU B CD1 1 
ATOM   7241  C CD2 . LEU B 1 437 ? 116.253 110.687 129.384 1.00 27.16  ? 437  LEU B CD2 1 
ATOM   7242  N N   . PHE B 1 438 ? 121.171 111.777 128.498 1.00 35.55  ? 438  PHE B N   1 
ATOM   7243  C CA  . PHE B 1 438 ? 121.691 112.810 127.616 1.00 35.55  ? 438  PHE B CA  1 
ATOM   7244  C C   . PHE B 1 438 ? 123.131 112.563 127.222 1.00 35.55  ? 438  PHE B C   1 
ATOM   7245  O O   . PHE B 1 438 ? 123.766 113.444 126.648 1.00 35.55  ? 438  PHE B O   1 
ATOM   7246  C CB  . PHE B 1 438 ? 121.547 114.184 128.257 1.00 35.55  ? 438  PHE B CB  1 
ATOM   7247  C CG  . PHE B 1 438 ? 120.145 114.663 128.301 1.00 35.55  ? 438  PHE B CG  1 
ATOM   7248  C CD1 . PHE B 1 438 ? 119.414 114.772 127.142 1.00 35.55  ? 438  PHE B CD1 1 
ATOM   7249  C CD2 . PHE B 1 438 ? 119.548 114.973 129.495 1.00 35.55  ? 438  PHE B CD2 1 
ATOM   7250  C CE1 . PHE B 1 438 ? 118.123 115.189 127.173 1.00 35.55  ? 438  PHE B CE1 1 
ATOM   7251  C CE2 . PHE B 1 438 ? 118.260 115.388 129.526 1.00 35.55  ? 438  PHE B CE2 1 
ATOM   7252  C CZ  . PHE B 1 438 ? 117.547 115.495 128.362 1.00 35.55  ? 438  PHE B CZ  1 
ATOM   7253  N N   . LEU B 1 439 ? 123.669 111.398 127.544 1.00 26.05  ? 439  LEU B N   1 
ATOM   7254  C CA  . LEU B 1 439 ? 124.835 110.893 126.844 1.00 26.05  ? 439  LEU B CA  1 
ATOM   7255  C C   . LEU B 1 439 ? 124.449 109.999 125.681 1.00 26.05  ? 439  LEU B C   1 
ATOM   7256  O O   . LEU B 1 439 ? 125.179 109.948 124.689 1.00 26.05  ? 439  LEU B O   1 
ATOM   7257  C CB  . LEU B 1 439 ? 125.744 110.119 127.801 1.00 26.05  ? 439  LEU B CB  1 
ATOM   7258  C CG  . LEU B 1 439 ? 127.088 109.632 127.278 1.00 26.05  ? 439  LEU B CG  1 
ATOM   7259  C CD1 . LEU B 1 439 ? 127.827 110.774 126.658 1.00 26.05  ? 439  LEU B CD1 1 
ATOM   7260  C CD2 . LEU B 1 439 ? 127.891 109.022 128.382 1.00 26.05  ? 439  LEU B CD2 1 
ATOM   7261  N N   . HIS B 1 440 ? 123.304 109.324 125.756 1.00 35.55  ? 440  HIS B N   1 
ATOM   7262  C CA  . HIS B 1 440 ? 122.855 108.492 124.656 1.00 35.55  ? 440  HIS B CA  1 
ATOM   7263  C C   . HIS B 1 440 ? 122.298 109.288 123.495 1.00 35.55  ? 440  HIS B C   1 
ATOM   7264  O O   . HIS B 1 440 ? 122.597 108.959 122.346 1.00 35.55  ? 440  HIS B O   1 
ATOM   7265  C CB  . HIS B 1 440 ? 121.799 107.507 125.118 1.00 35.55  ? 440  HIS B CB  1 
ATOM   7266  C CG  . HIS B 1 440 ? 121.778 106.255 124.310 1.00 35.55  ? 440  HIS B CG  1 
ATOM   7267  N ND1 . HIS B 1 440 ? 121.112 105.121 124.707 1.00 35.55  ? 440  HIS B ND1 1 
ATOM   7268  C CD2 . HIS B 1 440 ? 122.359 105.957 123.126 1.00 35.55  ? 440  HIS B CD2 1 
ATOM   7269  C CE1 . HIS B 1 440 ? 121.287 104.176 123.806 1.00 35.55  ? 440  HIS B CE1 1 
ATOM   7270  N NE2 . HIS B 1 440 ? 122.031 104.661 122.831 1.00 35.55  ? 440  HIS B NE2 1 
ATOM   7271  N N   . LEU B 1 441 ? 121.493 110.311 123.754 1.00 27.85  ? 441  LEU B N   1 
ATOM   7272  C CA  . LEU B 1 441 ? 121.010 111.198 122.711 1.00 27.85  ? 441  LEU B CA  1 
ATOM   7273  C C   . LEU B 1 441 ? 122.131 111.952 122.024 1.00 27.85  ? 441  LEU B C   1 
ATOM   7274  O O   . LEU B 1 441 ? 122.010 112.262 120.843 1.00 27.85  ? 441  LEU B O   1 
ATOM   7275  C CB  . LEU B 1 441 ? 119.999 112.184 123.298 1.00 27.85  ? 441  LEU B CB  1 
ATOM   7276  C CG  . LEU B 1 441 ? 119.369 113.259 122.427 1.00 27.85  ? 441  LEU B CG  1 
ATOM   7277  C CD1 . LEU B 1 441 ? 118.586 112.628 121.308 1.00 27.85  ? 441  LEU B CD1 1 
ATOM   7278  C CD2 . LEU B 1 441 ? 118.489 114.141 123.274 1.00 27.85  ? 441  LEU B CD2 1 
ATOM   7279  N N   . PHE B 1 442 ? 123.226 112.219 122.715 1.00 35.55  ? 442  PHE B N   1 
ATOM   7280  C CA  . PHE B 1 442 ? 124.393 112.780 122.064 1.00 35.55  ? 442  PHE B CA  1 
ATOM   7281  C C   . PHE B 1 442 ? 125.058 111.773 121.145 1.00 35.55  ? 442  PHE B C   1 
ATOM   7282  O O   . PHE B 1 442 ? 125.393 112.114 120.011 1.00 35.55  ? 442  PHE B O   1 
ATOM   7283  C CB  . PHE B 1 442 ? 125.387 113.273 123.104 1.00 35.55  ? 442  PHE B CB  1 
ATOM   7284  C CG  . PHE B 1 442 ? 126.731 113.578 122.556 1.00 35.55  ? 442  PHE B CG  1 
ATOM   7285  C CD1 . PHE B 1 442 ? 127.806 112.780 122.861 1.00 35.55  ? 442  PHE B CD1 1 
ATOM   7286  C CD2 . PHE B 1 442 ? 126.931 114.671 121.755 1.00 35.55  ? 442  PHE B CD2 1 
ATOM   7287  C CE1 . PHE B 1 442 ? 129.053 113.052 122.356 1.00 35.55  ? 442  PHE B CE1 1 
ATOM   7288  C CE2 . PHE B 1 442 ? 128.181 114.950 121.250 1.00 35.55  ? 442  PHE B CE2 1 
ATOM   7289  C CZ  . PHE B 1 442 ? 129.239 114.138 121.549 1.00 35.55  ? 442  PHE B CZ  1 
ATOM   7290  N N   . LEU B 1 443 ? 125.239 110.527 121.588 1.00 21.25  ? 443  LEU B N   1 
ATOM   7291  C CA  . LEU B 1 443 ? 125.864 109.509 120.746 1.00 21.25  ? 443  LEU B CA  1 
ATOM   7292  C C   . LEU B 1 443 ? 124.953 109.003 119.643 1.00 21.25  ? 443  LEU B C   1 
ATOM   7293  O O   . LEU B 1 443 ? 125.432 108.312 118.746 1.00 21.25  ? 443  LEU B O   1 
ATOM   7294  C CB  . LEU B 1 443 ? 126.332 108.326 121.583 1.00 21.25  ? 443  LEU B CB  1 
ATOM   7295  C CG  . LEU B 1 443 ? 127.436 108.665 122.558 1.00 21.25  ? 443  LEU B CG  1 
ATOM   7296  C CD1 . LEU B 1 443 ? 127.409 107.692 123.650 1.00 21.25  ? 443  LEU B CD1 1 
ATOM   7297  C CD2 . LEU B 1 443 ? 128.740 108.598 121.863 1.00 21.25  ? 443  LEU B CD2 1 
ATOM   7298  N N   . TYR B 1 444 ? 123.665 109.304 119.692 1.00 19.24  ? 444  TYR B N   1 
ATOM   7299  C CA  . TYR B 1 444 ? 122.798 109.170 118.538 1.00 19.24  ? 444  TYR B CA  1 
ATOM   7300  C C   . TYR B 1 444 ? 123.017 110.299 117.543 1.00 19.24  ? 444  TYR B C   1 
ATOM   7301  O O   . TYR B 1 444 ? 122.662 110.171 116.374 1.00 19.24  ? 444  TYR B O   1 
ATOM   7302  C CB  . TYR B 1 444 ? 121.345 109.130 118.993 1.00 19.24  ? 444  TYR B CB  1 
ATOM   7303  C CG  . TYR B 1 444 ? 120.348 108.966 117.888 1.00 19.24  ? 444  TYR B CG  1 
ATOM   7304  C CD1 . TYR B 1 444 ? 119.247 109.795 117.805 1.00 19.24  ? 444  TYR B CD1 1 
ATOM   7305  C CD2 . TYR B 1 444 ? 120.503 107.981 116.928 1.00 19.24  ? 444  TYR B CD2 1 
ATOM   7306  C CE1 . TYR B 1 444 ? 118.326 109.654 116.793 1.00 19.24  ? 444  TYR B CE1 1 
ATOM   7307  C CE2 . TYR B 1 444 ? 119.592 107.833 115.907 1.00 19.24  ? 444  TYR B CE2 1 
ATOM   7308  C CZ  . TYR B 1 444 ? 118.504 108.670 115.848 1.00 19.24  ? 444  TYR B CZ  1 
ATOM   7309  O OH  . TYR B 1 444 ? 117.589 108.522 114.839 1.00 19.24  ? 444  TYR B OH  1 
ATOM   7310  N N   . GLY B 1 445 ? 123.638 111.383 117.968 1.00 15.85  ? 445  GLY B N   1 
ATOM   7311  C CA  . GLY B 1 445 ? 123.881 112.478 117.071 1.00 15.85  ? 445  GLY B CA  1 
ATOM   7312  C C   . GLY B 1 445 ? 125.325 112.524 116.677 1.00 15.85  ? 445  GLY B C   1 
ATOM   7313  O O   . GLY B 1 445 ? 125.726 113.323 115.834 1.00 15.85  ? 445  GLY B O   1 
ATOM   7314  N N   . CYS B 1 446 ? 126.127 111.688 117.304 1.00 16.26  ? 446  CYS B N   1 
ATOM   7315  C CA  . CYS B 1 446 ? 127.472 111.453 116.830 1.00 16.26  ? 446  CYS B CA  1 
ATOM   7316  C C   . CYS B 1 446 ? 127.511 110.230 115.930 1.00 16.26  ? 446  CYS B C   1 
ATOM   7317  O O   . CYS B 1 446 ? 128.582 109.827 115.477 1.00 16.26  ? 446  CYS B O   1 
ATOM   7318  C CB  . CYS B 1 446 ? 128.415 111.316 118.021 1.00 16.26  ? 446  CYS B CB  1 
ATOM   7319  S SG  . CYS B 1 446 ? 130.174 111.471 117.675 1.00 16.26  ? 446  CYS B SG  1 
ATOM   7320  N N   . ASN B 1 447 ? 126.346 109.634 115.663 1.00 16.95  ? 447  ASN B N   1 
ATOM   7321  C CA  . ASN B 1 447 ? 126.195 108.542 114.716 1.00 16.95  ? 447  ASN B CA  1 
ATOM   7322  C C   . ASN B 1 447 ? 125.464 108.945 113.453 1.00 16.95  ? 447  ASN B C   1 
ATOM   7323  O O   . ASN B 1 447 ? 125.659 108.297 112.428 1.00 16.95  ? 447  ASN B O   1 
ATOM   7324  C CB  . ASN B 1 447 ? 125.456 107.365 115.356 1.00 16.95  ? 447  ASN B CB  1 
ATOM   7325  C CG  . ASN B 1 447 ? 126.358 106.526 116.211 1.00 16.95  ? 447  ASN B CG  1 
ATOM   7326  O OD1 . ASN B 1 447 ? 127.573 106.545 116.046 1.00 16.95  ? 447  ASN B OD1 1 
ATOM   7327  N ND2 . ASN B 1 447 ? 125.775 105.790 117.138 1.00 16.95  ? 447  ASN B ND2 1 
ATOM   7328  N N   . ILE B 1 448 ? 124.639 109.990 113.485 1.00 16.58  ? 448  ILE B N   1 
ATOM   7329  C CA  . ILE B 1 448 ? 124.180 110.609 112.253 1.00 16.58  ? 448  ILE B CA  1 
ATOM   7330  C C   . ILE B 1 448 ? 125.305 111.377 111.580 1.00 16.58  ? 448  ILE B C   1 
ATOM   7331  O O   . ILE B 1 448 ? 125.361 111.430 110.360 1.00 16.58  ? 448  ILE B O   1 
ATOM   7332  C CB  . ILE B 1 448 ? 122.948 111.501 112.483 1.00 16.58  ? 448  ILE B CB  1 
ATOM   7333  C CG1 . ILE B 1 448 ? 121.891 110.743 113.272 1.00 16.58  ? 448  ILE B CG1 1 
ATOM   7334  C CG2 . ILE B 1 448 ? 122.307 111.893 111.177 1.00 16.58  ? 448  ILE B CG2 1 
ATOM   7335  C CD1 . ILE B 1 448 ? 120.598 111.500 113.487 1.00 16.58  ? 448  ILE B CD1 1 
ATOM   7336  N N   . PHE B 1 449 ? 126.258 111.890 112.343 1.00 17.42  ? 449  PHE B N   1 
ATOM   7337  C CA  . PHE B 1 449 ? 127.447 112.457 111.734 1.00 17.42  ? 449  PHE B CA  1 
ATOM   7338  C C   . PHE B 1 449 ? 128.334 111.402 111.092 1.00 17.42  ? 449  PHE B C   1 
ATOM   7339  O O   . PHE B 1 449 ? 129.063 111.724 110.156 1.00 17.42  ? 449  PHE B O   1 
ATOM   7340  C CB  . PHE B 1 449 ? 128.256 113.251 112.766 1.00 17.42  ? 449  PHE B CB  1 
ATOM   7341  C CG  . PHE B 1 449 ? 129.534 113.823 112.228 1.00 17.42  ? 449  PHE B CG  1 
ATOM   7342  C CD1 . PHE B 1 449 ? 130.752 113.273 112.571 1.00 17.42  ? 449  PHE B CD1 1 
ATOM   7343  C CD2 . PHE B 1 449 ? 129.515 114.889 111.356 1.00 17.42  ? 449  PHE B CD2 1 
ATOM   7344  C CE1 . PHE B 1 449 ? 131.928 113.787 112.064 1.00 17.42  ? 449  PHE B CE1 1 
ATOM   7345  C CE2 . PHE B 1 449 ? 130.688 115.409 110.851 1.00 17.42  ? 449  PHE B CE2 1 
ATOM   7346  C CZ  . PHE B 1 449 ? 131.894 114.856 111.207 1.00 17.42  ? 449  PHE B CZ  1 
ATOM   7347  N N   . MET B 1 450 ? 128.259 110.144 111.521 1.00 24.01  ? 450  MET B N   1 
ATOM   7348  C CA  . MET B 1 450 ? 129.022 109.092 110.865 1.00 24.01  ? 450  MET B CA  1 
ATOM   7349  C C   . MET B 1 450 ? 128.218 108.290 109.856 1.00 24.01  ? 450  MET B C   1 
ATOM   7350  O O   . MET B 1 450 ? 128.818 107.603 109.030 1.00 24.01  ? 450  MET B O   1 
ATOM   7351  C CB  . MET B 1 450 ? 129.612 108.126 111.897 1.00 24.01  ? 450  MET B CB  1 
ATOM   7352  C CG  . MET B 1 450 ? 130.624 108.747 112.828 1.00 24.01  ? 450  MET B CG  1 
ATOM   7353  S SD  . MET B 1 450 ? 130.894 107.734 114.287 1.00 24.01  ? 450  MET B SD  1 
ATOM   7354  C CE  . MET B 1 450 ? 132.266 108.613 115.007 1.00 24.01  ? 450  MET B CE  1 
ATOM   7355  N N   . TRP B 1 451 ? 126.887 108.359 109.900 1.00 22.61  ? 451  TRP B N   1 
ATOM   7356  C CA  . TRP B 1 451 ? 126.066 107.738 108.867 1.00 22.61  ? 451  TRP B CA  1 
ATOM   7357  C C   . TRP B 1 451 ? 126.020 108.587 107.607 1.00 22.61  ? 451  TRP B C   1 
ATOM   7358  O O   . TRP B 1 451 ? 126.118 108.057 106.497 1.00 22.61  ? 451  TRP B O   1 
ATOM   7359  C CB  . TRP B 1 451 ? 124.653 107.493 109.387 1.00 22.61  ? 451  TRP B CB  1 
ATOM   7360  C CG  . TRP B 1 451 ? 124.591 106.335 110.303 1.00 22.61  ? 451  TRP B CG  1 
ATOM   7361  C CD1 . TRP B 1 451 ? 125.519 105.365 110.436 1.00 22.61  ? 451  TRP B CD1 1 
ATOM   7362  C CD2 . TRP B 1 451 ? 123.557 106.030 111.239 1.00 22.61  ? 451  TRP B CD2 1 
ATOM   7363  N NE1 . TRP B 1 451 ? 125.129 104.461 111.384 1.00 22.61  ? 451  TRP B NE1 1 
ATOM   7364  C CE2 . TRP B 1 451 ? 123.922 104.854 111.891 1.00 22.61  ? 451  TRP B CE2 1 
ATOM   7365  C CE3 . TRP B 1 451 ? 122.361 106.644 111.591 1.00 22.61  ? 451  TRP B CE3 1 
ATOM   7366  C CZ2 . TRP B 1 451 ? 123.133 104.277 112.860 1.00 22.61  ? 451  TRP B CZ2 1 
ATOM   7367  C CZ3 . TRP B 1 451 ? 121.574 106.061 112.547 1.00 22.61  ? 451  TRP B CZ3 1 
ATOM   7368  C CH2 . TRP B 1 451 ? 121.963 104.898 113.173 1.00 22.61  ? 451  TRP B CH2 1 
ATOM   7369  N N   . ARG B 1 452 ? 125.857 109.901 107.763 1.00 26.54  ? 452  ARG B N   1 
ATOM   7370  C CA  . ARG B 1 452 ? 125.877 110.795 106.614 1.00 26.54  ? 452  ARG B CA  1 
ATOM   7371  C C   . ARG B 1 452 ? 127.246 110.817 105.961 1.00 26.54  ? 452  ARG B C   1 
ATOM   7372  O O   . ARG B 1 452 ? 127.349 110.857 104.733 1.00 26.54  ? 452  ARG B O   1 
ATOM   7373  C CB  . ARG B 1 452 ? 125.473 112.203 107.036 1.00 26.54  ? 452  ARG B CB  1 
ATOM   7374  C CG  . ARG B 1 452 ? 124.061 112.320 107.576 1.00 26.54  ? 452  ARG B CG  1 
ATOM   7375  C CD  . ARG B 1 452 ? 123.018 112.231 106.497 1.00 26.54  ? 452  ARG B CD  1 
ATOM   7376  N NE  . ARG B 1 452 ? 121.777 112.884 106.895 1.00 26.54  ? 452  ARG B NE  1 
ATOM   7377  C CZ  . ARG B 1 452 ? 121.556 114.190 106.800 1.00 26.54  ? 452  ARG B CZ  1 
ATOM   7378  N NH1 . ARG B 1 452 ? 122.495 114.993 106.322 1.00 26.54  ? 452  ARG B NH1 1 
ATOM   7379  N NH2 . ARG B 1 452 ? 120.393 114.697 107.180 1.00 26.54  ? 452  ARG B NH2 1 
ATOM   7380  N N   . LYS B 1 453 ? 128.311 110.745 106.755 1.00 23.40  ? 453  LYS B N   1 
ATOM   7381  C CA  . LYS B 1 453 ? 129.664 110.864 106.230 1.00 23.40  ? 453  LYS B CA  1 
ATOM   7382  C C   . LYS B 1 453 ? 130.180 109.561 105.629 1.00 23.40  ? 453  LYS B C   1 
ATOM   7383  O O   . LYS B 1 453 ? 131.338 109.490 105.210 1.00 23.40  ? 453  LYS B O   1 
ATOM   7384  C CB  . LYS B 1 453 ? 130.616 111.362 107.310 1.00 23.40  ? 453  LYS B CB  1 
ATOM   7385  C CG  . LYS B 1 453 ? 131.652 112.336 106.801 1.00 23.40  ? 453  LYS B CG  1 
ATOM   7386  C CD  . LYS B 1 453 ? 132.636 112.692 107.881 1.00 23.40  ? 453  LYS B CD  1 
ATOM   7387  C CE  . LYS B 1 453 ? 133.512 111.501 108.216 1.00 23.40  ? 453  LYS B CE  1 
ATOM   7388  N NZ  . LYS B 1 453 ? 134.400 111.147 107.078 1.00 23.40  ? 453  LYS B NZ  1 
ATOM   7389  N N   . ALA B 1 454 ? 129.356 108.521 105.591 1.00 27.60  ? 454  ALA B N   1 
ATOM   7390  C CA  . ALA B 1 454 ? 129.657 107.357 104.773 1.00 27.60  ? 454  ALA B CA  1 
ATOM   7391  C C   . ALA B 1 454 ? 128.471 106.922 103.935 1.00 27.60  ? 454  ALA B C   1 
ATOM   7392  O O   . ALA B 1 454 ? 128.565 105.889 103.268 1.00 27.60  ? 454  ALA B O   1 
ATOM   7393  C CB  . ALA B 1 454 ? 130.130 106.184 105.636 1.00 27.60  ? 454  ALA B CB  1 
ATOM   7394  N N   . ARG B 1 455 ? 127.366 107.674 103.966 1.00 36.15  ? 455  ARG B N   1 
ATOM   7395  C CA  . ARG B 1 455 ? 126.179 107.509 103.123 1.00 36.15  ? 455  ARG B CA  1 
ATOM   7396  C C   . ARG B 1 455 ? 125.522 106.147 103.364 1.00 36.15  ? 455  ARG B C   1 
ATOM   7397  O O   . ARG B 1 455 ? 125.285 105.358 102.453 1.00 36.15  ? 455  ARG B O   1 
ATOM   7398  C CB  . ARG B 1 455 ? 126.520 107.730 101.640 1.00 36.15  ? 455  ARG B CB  1 
ATOM   7399  C CG  . ARG B 1 455 ? 127.132 109.097 101.343 1.00 36.15  ? 455  ARG B CG  1 
ATOM   7400  C CD  . ARG B 1 455 ? 127.896 109.107 100.034 1.00 36.15  ? 455  ARG B CD  1 
ATOM   7401  N NE  . ARG B 1 455 ? 129.100 108.285 100.075 1.00 36.15  ? 455  ARG B NE  1 
ATOM   7402  C CZ  . ARG B 1 455 ? 130.325 108.765 100.263 1.00 36.15  ? 455  ARG B CZ  1 
ATOM   7403  N NH1 . ARG B 1 455 ? 130.508 110.067 100.426 1.00 36.15  ? 455  ARG B NH1 1 
ATOM   7404  N NH2 . ARG B 1 455 ? 131.368 107.948 100.283 1.00 36.15  ? 455  ARG B NH2 1 
ATOM   7405  N N   . ILE B 1 456 ? 125.200 105.916 104.631 1.00 26.05  ? 456  ILE B N   1 
ATOM   7406  C CA  . ILE B 1 456 ? 124.736 104.609 105.073 1.00 26.05  ? 456  ILE B CA  1 
ATOM   7407  C C   . ILE B 1 456 ? 123.208 104.599 105.044 1.00 26.05  ? 456  ILE B C   1 
ATOM   7408  O O   . ILE B 1 456 ? 122.574 103.573 105.323 1.00 26.05  ? 456  ILE B O   1 
ATOM   7409  C CB  . ILE B 1 456 ? 125.365 104.284 106.444 1.00 26.05  ? 456  ILE B CB  1 
ATOM   7410  C CG1 . ILE B 1 456 ? 126.875 104.487 106.310 1.00 26.05  ? 456  ILE B CG1 1 
ATOM   7411  C CG2 . ILE B 1 456 ? 125.167 102.854 106.864 1.00 26.05  ? 456  ILE B CG2 1 
ATOM   7412  C CD1 . ILE B 1 456 ? 127.763 103.848 107.380 1.00 26.05  ? 456  ILE B CD1 1 
ATOM   7413  N N   . ASN B 1 457 ? 122.618 105.717 104.612 1.00 27.85  ? 457  ASN B N   1 
ATOM   7414  C CA  . ASN B 1 457 ? 121.197 105.830 104.245 1.00 27.85  ? 457  ASN B CA  1 
ATOM   7415  C C   . ASN B 1 457 ? 120.284 105.411 105.401 1.00 27.85  ? 457  ASN B C   1 
ATOM   7416  O O   . ASN B 1 457 ? 119.638 104.365 105.396 1.00 27.85  ? 457  ASN B O   1 
ATOM   7417  C CB  . ASN B 1 457 ? 120.905 105.038 102.969 1.00 27.85  ? 457  ASN B CB  1 
ATOM   7418  C CG  . ASN B 1 457 ? 119.458 105.122 102.542 1.00 27.85  ? 457  ASN B CG  1 
ATOM   7419  O OD1 . ASN B 1 457 ? 118.782 106.116 102.785 1.00 27.85  ? 457  ASN B OD1 1 
ATOM   7420  N ND2 . ASN B 1 457 ? 118.963 104.049 101.947 1.00 27.85  ? 457  ASN B ND2 1 
ATOM   7421  N N   . TYR B 1 458 ? 120.311 106.216 106.449 1.00 29.12  ? 458  TYR B N   1 
ATOM   7422  C CA  . TYR B 1 458 ? 119.615 105.805 107.650 1.00 29.12  ? 458  TYR B CA  1 
ATOM   7423  C C   . TYR B 1 458 ? 118.123 106.065 107.573 1.00 29.12  ? 458  TYR B C   1 
ATOM   7424  O O   . TYR B 1 458 ? 117.368 105.451 108.328 1.00 29.12  ? 458  TYR B O   1 
ATOM   7425  C CB  . TYR B 1 458 ? 120.233 106.499 108.853 1.00 29.12  ? 458  TYR B CB  1 
ATOM   7426  C CG  . TYR B 1 458 ? 119.788 107.912 109.102 1.00 29.12  ? 458  TYR B CG  1 
ATOM   7427  C CD1 . TYR B 1 458 ? 120.295 108.958 108.355 1.00 29.12  ? 458  TYR B CD1 1 
ATOM   7428  C CD2 . TYR B 1 458 ? 118.886 108.204 110.115 1.00 29.12  ? 458  TYR B CD2 1 
ATOM   7429  C CE1 . TYR B 1 458 ? 119.892 110.251 108.591 1.00 29.12  ? 458  TYR B CE1 1 
ATOM   7430  C CE2 . TYR B 1 458 ? 118.483 109.488 110.359 1.00 29.12  ? 458  TYR B CE2 1 
ATOM   7431  C CZ  . TYR B 1 458 ? 118.984 110.506 109.596 1.00 29.12  ? 458  TYR B CZ  1 
ATOM   7432  O OH  . TYR B 1 458 ? 118.575 111.792 109.844 1.00 29.12  ? 458  TYR B OH  1 
ATOM   7433  N N   . SER B 1 459 ? 117.680 106.938 106.670 1.00 31.63  ? 459  SER B N   1 
ATOM   7434  C CA  . SER B 1 459 ? 116.268 107.301 106.628 1.00 31.63  ? 459  SER B CA  1 
ATOM   7435  C C   . SER B 1 459 ? 115.419 106.223 105.973 1.00 31.63  ? 459  SER B C   1 
ATOM   7436  O O   . SER B 1 459 ? 114.273 106.006 106.383 1.00 31.63  ? 459  SER B O   1 
ATOM   7437  C CB  . SER B 1 459 ? 116.088 108.625 105.892 1.00 31.63  ? 459  SER B CB  1 
ATOM   7438  O OG  . SER B 1 459 ? 114.715 108.926 105.725 1.00 31.63  ? 459  SER B OG  1 
ATOM   7439  N N   . PHE B 1 460 ? 115.952 105.543 104.959 1.00 30.96  ? 460  PHE B N   1 
ATOM   7440  C CA  . PHE B 1 460 ? 115.185 104.515 104.270 1.00 30.96  ? 460  PHE B CA  1 
ATOM   7441  C C   . PHE B 1 460 ? 115.189 103.193 105.028 1.00 30.96  ? 460  PHE B C   1 
ATOM   7442  O O   . PHE B 1 460 ? 114.164 102.504 105.055 1.00 30.96  ? 460  PHE B O   1 
ATOM   7443  C CB  . PHE B 1 460 ? 115.726 104.319 102.853 1.00 30.96  ? 460  PHE B CB  1 
ATOM   7444  C CG  . PHE B 1 460 ? 115.266 103.051 102.201 1.00 30.96  ? 460  PHE B CG  1 
ATOM   7445  C CD1 . PHE B 1 460 ? 113.930 102.859 101.894 1.00 30.96  ? 460  PHE B CD1 1 
ATOM   7446  C CD2 . PHE B 1 460 ? 116.172 102.050 101.897 1.00 30.96  ? 460  PHE B CD2 1 
ATOM   7447  C CE1 . PHE B 1 460 ? 113.505 101.690 101.303 1.00 30.96  ? 460  PHE B CE1 1 
ATOM   7448  C CE2 . PHE B 1 460 ? 115.753 100.882 101.307 1.00 30.96  ? 460  PHE B CE2 1 
ATOM   7449  C CZ  . PHE B 1 460 ? 114.418 100.704 101.005 1.00 30.96  ? 460  PHE B CZ  1 
ATOM   7450  N N   . ILE B 1 461 ? 116.327 102.828 105.632 1.00 27.10  ? 461  ILE B N   1 
ATOM   7451  C CA  . ILE B 1 461 ? 116.410 101.609 106.434 1.00 27.10  ? 461  ILE B CA  1 
ATOM   7452  C C   . ILE B 1 461 ? 115.473 101.693 107.626 1.00 27.10  ? 461  ILE B C   1 
ATOM   7453  O O   . ILE B 1 461 ? 114.685 100.776 107.875 1.00 27.10  ? 461  ILE B O   1 
ATOM   7454  C CB  . ILE B 1 461 ? 117.857 101.356 106.884 1.00 27.10  ? 461  ILE B CB  1 
ATOM   7455  C CG1 . ILE B 1 461 ? 118.771 101.177 105.684 1.00 27.10  ? 461  ILE B CG1 1 
ATOM   7456  C CG2 . ILE B 1 461 ? 117.926 100.120 107.709 1.00 27.10  ? 461  ILE B CG2 1 
ATOM   7457  C CD1 . ILE B 1 461 ? 120.225 101.108 106.050 1.00 27.10  ? 461  ILE B CD1 1 
ATOM   7458  N N   . PHE B 1 462 ? 115.498 102.817 108.342 1.00 28.96  ? 462  PHE B N   1 
ATOM   7459  C CA  . PHE B 1 462 ? 114.590 103.044 109.459 1.00 28.96  ? 462  PHE B CA  1 
ATOM   7460  C C   . PHE B 1 462 ? 113.154 103.306 109.020 1.00 28.96  ? 462  PHE B C   1 
ATOM   7461  O O   . PHE B 1 462 ? 112.274 103.352 109.886 1.00 28.96  ? 462  PHE B O   1 
ATOM   7462  C CB  . PHE B 1 462 ? 115.062 104.231 110.308 1.00 28.96  ? 462  PHE B CB  1 
ATOM   7463  C CG  . PHE B 1 462 ? 116.380 104.018 111.021 1.00 28.96  ? 462  PHE B CG  1 
ATOM   7464  C CD1 . PHE B 1 462 ? 116.877 102.755 111.261 1.00 28.96  ? 462  PHE B CD1 1 
ATOM   7465  C CD2 . PHE B 1 462 ? 117.099 105.103 111.485 1.00 28.96  ? 462  PHE B CD2 1 
ATOM   7466  C CE1 . PHE B 1 462 ? 118.070 102.590 111.922 1.00 28.96  ? 462  PHE B CE1 1 
ATOM   7467  C CE2 . PHE B 1 462 ? 118.287 104.935 112.143 1.00 28.96  ? 462  PHE B CE2 1 
ATOM   7468  C CZ  . PHE B 1 462 ? 118.770 103.683 112.360 1.00 28.96  ? 462  PHE B CZ  1 
ATOM   7469  N N   . GLU B 1 463 ? 112.918 103.471 107.711 1.00 33.21  ? 463  GLU B N   1 
ATOM   7470  C CA  . GLU B 1 463 ? 111.640 103.874 107.108 1.00 33.21  ? 463  GLU B CA  1 
ATOM   7471  C C   . GLU B 1 463 ? 111.173 105.218 107.669 1.00 33.21  ? 463  GLU B C   1 
ATOM   7472  O O   . GLU B 1 463 ? 110.037 105.380 108.120 1.00 33.21  ? 463  GLU B O   1 
ATOM   7473  C CB  . GLU B 1 463 ? 110.554 102.799 107.269 1.00 33.21  ? 463  GLU B CB  1 
ATOM   7474  C CG  . GLU B 1 463 ? 110.752 101.562 106.418 1.00 33.21  ? 463  GLU B CG  1 
ATOM   7475  C CD  . GLU B 1 463 ? 111.661 100.560 107.087 1.00 33.21  ? 463  GLU B CD  1 
ATOM   7476  O OE1 . GLU B 1 463 ? 112.309 99.759  106.382 1.00 33.21  ? 463  GLU B OE1 1 
ATOM   7477  O OE2 . GLU B 1 463 ? 111.736 100.587 108.329 1.00 33.21  ? 463  GLU B OE2 1 
ATOM   7478  N N   . LEU B 1 464 ? 112.077 106.195 107.621 1.00 31.13  ? 464  LEU B N   1 
ATOM   7479  C CA  . LEU B 1 464 ? 111.782 107.491 108.218 1.00 31.13  ? 464  LEU B CA  1 
ATOM   7480  C C   . LEU B 1 464 ? 110.882 108.330 107.318 1.00 31.13  ? 464  LEU B C   1 
ATOM   7481  O O   . LEU B 1 464 ? 109.759 108.684 107.696 1.00 31.13  ? 464  LEU B O   1 
ATOM   7482  C CB  . LEU B 1 464 ? 113.083 108.234 108.516 1.00 31.13  ? 464  LEU B CB  1 
ATOM   7483  C CG  . LEU B 1 464 ? 113.802 107.828 109.793 1.00 31.13  ? 464  LEU B CG  1 
ATOM   7484  C CD1 . LEU B 1 464 ? 115.032 108.666 109.966 1.00 31.13  ? 464  LEU B CD1 1 
ATOM   7485  C CD2 . LEU B 1 464 ? 112.887 108.005 110.964 1.00 31.13  ? 464  LEU B CD2 1 
ATOM   7486  N N   . GLY B 1 465 ? 111.352 108.641 106.118 1.00 41.21  ? 465  GLY B N   1 
ATOM   7487  C CA  . GLY B 1 465 ? 110.699 109.591 105.240 1.00 41.21  ? 465  GLY B CA  1 
ATOM   7488  C C   . GLY B 1 465 ? 111.436 110.918 105.242 1.00 41.21  ? 465  GLY B C   1 
ATOM   7489  O O   . GLY B 1 465 ? 112.511 111.066 105.825 1.00 41.21  ? 465  GLY B O   1 
ATOM   7490  N N   . SER B 1 466 ? 110.836 111.895 104.560 1.00 44.21  ? 466  SER B N   1 
ATOM   7491  C CA  . SER B 1 466 ? 111.416 113.232 104.561 1.00 44.21  ? 466  SER B CA  1 
ATOM   7492  C C   . SER B 1 466 ? 111.169 113.877 105.918 1.00 44.21  ? 466  SER B C   1 
ATOM   7493  O O   . SER B 1 466 ? 112.123 114.075 106.676 1.00 44.21  ? 466  SER B O   1 
ATOM   7494  C CB  . SER B 1 466 ? 110.831 114.076 103.431 1.00 44.21  ? 466  SER B CB  1 
ATOM   7495  O OG  . SER B 1 466 ? 111.139 113.503 102.173 1.00 44.21  ? 466  SER B OG  1 
ATOM   7496  N N   . LYS B 1 467 ? 109.900 114.185 106.203 1.00 49.68  ? 467  LYS B N   1 
ATOM   7497  C CA  . LYS B 1 467 ? 109.299 114.294 107.543 1.00 49.68  ? 467  LYS B CA  1 
ATOM   7498  C C   . LYS B 1 467 ? 110.132 115.115 108.535 1.00 49.68  ? 467  LYS B C   1 
ATOM   7499  O O   . LYS B 1 467 ? 110.339 114.719 109.683 1.00 49.68  ? 467  LYS B O   1 
ATOM   7500  C CB  . LYS B 1 467 ? 109.033 112.891 108.094 1.00 49.68  ? 467  LYS B CB  1 
ATOM   7501  C CG  . LYS B 1 467 ? 107.859 112.758 109.062 1.00 49.68  ? 467  LYS B CG  1 
ATOM   7502  C CD  . LYS B 1 467 ? 107.880 111.387 109.725 1.00 49.68  ? 467  LYS B CD  1 
ATOM   7503  C CE  . LYS B 1 467 ? 106.773 111.241 110.745 1.00 49.68  ? 467  LYS B CE  1 
ATOM   7504  N NZ  . LYS B 1 467 ? 106.980 112.153 111.894 1.00 49.68  ? 467  LYS B NZ  1 
ATOM   7505  N N   . ASN B 1 468 ? 110.634 116.261 108.049 1.00 49.78  ? 468  ASN B N   1 
ATOM   7506  C CA  . ASN B 1 468 ? 111.464 117.203 108.816 1.00 49.78  ? 468  ASN B CA  1 
ATOM   7507  C C   . ASN B 1 468 ? 112.728 116.519 109.350 1.00 49.78  ? 468  ASN B C   1 
ATOM   7508  O O   . ASN B 1 468 ? 112.832 116.207 110.540 1.00 49.78  ? 468  ASN B O   1 
ATOM   7509  C CB  . ASN B 1 468 ? 110.678 117.866 109.958 1.00 49.78  ? 468  ASN B CB  1 
ATOM   7510  C CG  . ASN B 1 468 ? 109.575 118.775 109.463 1.00 49.78  ? 468  ASN B CG  1 
ATOM   7511  O OD1 . ASN B 1 468 ? 109.717 119.997 109.465 1.00 49.78  ? 468  ASN B OD1 1 
ATOM   7512  N ND2 . ASN B 1 468 ? 108.461 118.183 109.049 1.00 49.78  ? 468  ASN B ND2 1 
ATOM   7513  N N   . GLU B 1 469 ? 113.633 116.215 108.407 1.00 40.98  ? 469  GLU B N   1 
ATOM   7514  C CA  . GLU B 1 469 ? 114.877 115.495 108.691 1.00 40.98  ? 469  GLU B CA  1 
ATOM   7515  C C   . GLU B 1 469 ? 115.682 116.134 109.818 1.00 40.98  ? 469  GLU B C   1 
ATOM   7516  O O   . GLU B 1 469 ? 116.181 117.254 109.681 1.00 40.98  ? 469  GLU B O   1 
ATOM   7517  C CB  . GLU B 1 469 ? 115.768 115.437 107.442 1.00 40.98  ? 469  GLU B CB  1 
ATOM   7518  C CG  . GLU B 1 469 ? 115.315 114.549 106.291 1.00 40.98  ? 469  GLU B CG  1 
ATOM   7519  C CD  . GLU B 1 469 ? 114.743 115.339 105.132 1.00 40.98  ? 469  GLU B CD  1 
ATOM   7520  O OE1 . GLU B 1 469 ? 114.658 116.578 105.247 1.00 40.98  ? 469  GLU B OE1 1 
ATOM   7521  O OE2 . GLU B 1 469 ? 114.406 114.726 104.097 1.00 40.98  ? 469  GLU B OE2 1 
ATOM   7522  N N   . LEU B 1 470 ? 115.793 115.418 110.936 1.00 28.46  ? 470  LEU B N   1 
ATOM   7523  C CA  . LEU B 1 470 ? 116.716 115.800 111.994 1.00 28.46  ? 470  LEU B CA  1 
ATOM   7524  C C   . LEU B 1 470 ? 118.145 115.632 111.519 1.00 28.46  ? 470  LEU B C   1 
ATOM   7525  O O   . LEU B 1 470 ? 118.451 114.734 110.734 1.00 28.46  ? 470  LEU B O   1 
ATOM   7526  C CB  . LEU B 1 470 ? 116.491 114.971 113.257 1.00 28.46  ? 470  LEU B CB  1 
ATOM   7527  C CG  . LEU B 1 470 ? 115.599 115.576 114.336 1.00 28.46  ? 470  LEU B CG  1 
ATOM   7528  C CD1 . LEU B 1 470 ? 114.206 115.737 113.839 1.00 28.46  ? 470  LEU B CD1 1 
ATOM   7529  C CD2 . LEU B 1 470 ? 115.593 114.713 115.574 1.00 28.46  ? 470  LEU B CD2 1 
ATOM   7530  N N   . LYS B 1 471 ? 119.013 116.511 111.976 1.00 20.93  ? 471  LYS B N   1 
ATOM   7531  C CA  . LYS B 1 471 ? 120.408 116.459 111.594 1.00 20.93  ? 471  LYS B CA  1 
ATOM   7532  C C   . LYS B 1 471 ? 121.247 116.235 112.841 1.00 20.93  ? 471  LYS B C   1 
ATOM   7533  O O   . LYS B 1 471 ? 120.728 116.018 113.930 1.00 20.93  ? 471  LYS B O   1 
ATOM   7534  C CB  . LYS B 1 471 ? 120.808 117.738 110.864 1.00 20.93  ? 471  LYS B CB  1 
ATOM   7535  C CG  . LYS B 1 471 ? 120.104 117.947 109.544 1.00 20.93  ? 471  LYS B CG  1 
ATOM   7536  C CD  . LYS B 1 471 ? 120.541 119.253 108.914 1.00 20.93  ? 471  LYS B CD  1 
ATOM   7537  C CE  . LYS B 1 471 ? 121.956 119.155 108.373 1.00 20.93  ? 471  LYS B CE  1 
ATOM   7538  N NZ  . LYS B 1 471 ? 122.007 118.274 107.180 1.00 20.93  ? 471  LYS B NZ  1 
ATOM   7539  N N   . TYR B 1 472 ? 122.560 116.301 112.676 1.00 17.68  ? 472  TYR B N   1 
ATOM   7540  C CA  . TYR B 1 472 ? 123.472 116.235 113.805 1.00 17.68  ? 472  TYR B CA  1 
ATOM   7541  C C   . TYR B 1 472 ? 123.740 117.600 114.420 1.00 17.68  ? 472  TYR B C   1 
ATOM   7542  O O   . TYR B 1 472 ? 124.636 117.735 115.262 1.00 17.68  ? 472  TYR B O   1 
ATOM   7543  C CB  . TYR B 1 472 ? 124.778 115.565 113.392 1.00 17.68  ? 472  TYR B CB  1 
ATOM   7544  C CG  . TYR B 1 472 ? 125.639 116.367 112.457 1.00 17.68  ? 472  TYR B CG  1 
ATOM   7545  C CD1 . TYR B 1 472 ? 125.357 116.416 111.099 1.00 17.68  ? 472  TYR B CD1 1 
ATOM   7546  C CD2 . TYR B 1 472 ? 126.752 117.046 112.925 1.00 17.68  ? 472  TYR B CD2 1 
ATOM   7547  C CE1 . TYR B 1 472 ? 126.140 117.131 110.243 1.00 17.68  ? 472  TYR B CE1 1 
ATOM   7548  C CE2 . TYR B 1 472 ? 127.543 117.765 112.076 1.00 17.68  ? 472  TYR B CE2 1 
ATOM   7549  C CZ  . TYR B 1 472 ? 127.234 117.805 110.733 1.00 17.68  ? 472  TYR B CZ  1 
ATOM   7550  O OH  . TYR B 1 472 ? 128.023 118.528 109.868 1.00 17.68  ? 472  TYR B OH  1 
ATOM   7551  N N   . ARG B 1 473 ? 123.004 118.623 114.003 1.00 21.22  ? 473  ARG B N   1 
ATOM   7552  C CA  . ARG B 1 473 ? 122.964 119.888 114.707 1.00 21.22  ? 473  ARG B CA  1 
ATOM   7553  C C   . ARG B 1 473 ? 121.644 120.107 115.409 1.00 21.22  ? 473  ARG B C   1 
ATOM   7554  O O   . ARG B 1 473 ? 121.521 121.068 116.167 1.00 21.22  ? 473  ARG B O   1 
ATOM   7555  C CB  . ARG B 1 473 ? 123.210 121.060 113.746 1.00 21.22  ? 473  ARG B CB  1 
ATOM   7556  C CG  . ARG B 1 473 ? 124.438 120.921 112.877 1.00 21.22  ? 473  ARG B CG  1 
ATOM   7557  C CD  . ARG B 1 473 ? 125.106 122.259 112.624 1.00 21.22  ? 473  ARG B CD  1 
ATOM   7558  N NE  . ARG B 1 473 ? 126.466 122.091 112.128 1.00 21.22  ? 473  ARG B NE  1 
ATOM   7559  C CZ  . ARG B 1 473 ? 127.523 121.879 112.904 1.00 21.22  ? 473  ARG B CZ  1 
ATOM   7560  N NH1 . ARG B 1 473 ? 127.389 121.812 114.222 1.00 21.22  ? 473  ARG B NH1 1 
ATOM   7561  N NH2 . ARG B 1 473 ? 128.722 121.736 112.361 1.00 21.22  ? 473  ARG B NH2 1 
ATOM   7562  N N   . ASP B 1 474 ? 120.648 119.269 115.160 1.00 23.22  ? 474  ASP B N   1 
ATOM   7563  C CA  . ASP B 1 474 ? 119.381 119.357 115.856 1.00 23.22  ? 474  ASP B CA  1 
ATOM   7564  C C   . ASP B 1 474 ? 119.195 118.266 116.899 1.00 23.22  ? 474  ASP B C   1 
ATOM   7565  O O   . ASP B 1 474 ? 118.087 118.124 117.418 1.00 23.22  ? 474  ASP B O   1 
ATOM   7566  C CB  . ASP B 1 474 ? 118.212 119.306 114.866 1.00 23.22  ? 474  ASP B CB  1 
ATOM   7567  C CG  . ASP B 1 474 ? 118.279 120.399 113.813 1.00 23.22  ? 474  ASP B CG  1 
ATOM   7568  O OD1 . ASP B 1 474 ? 119.277 121.144 113.779 1.00 23.22  ? 474  ASP B OD1 1 
ATOM   7569  O OD2 . ASP B 1 474 ? 117.321 120.524 113.019 1.00 23.22  ? 474  ASP B OD2 1 
ATOM   7570  N N   . VAL B 1 475 ? 120.225 117.469 117.191 1.00 14.10  ? 475  VAL B N   1 
ATOM   7571  C CA  . VAL B 1 475 ? 120.238 116.588 118.355 1.00 14.10  ? 475  VAL B CA  1 
ATOM   7572  C C   . VAL B 1 475 ? 121.479 116.898 119.166 1.00 14.10  ? 475  VAL B C   1 
ATOM   7573  O O   . VAL B 1 475 ? 121.602 116.470 120.313 1.00 14.10  ? 475  VAL B O   1 
ATOM   7574  C CB  . VAL B 1 475 ? 120.203 115.104 117.977 1.00 14.10  ? 475  VAL B CB  1 
ATOM   7575  C CG1 . VAL B 1 475 ? 118.870 114.736 117.411 1.00 14.10  ? 475  VAL B CG1 1 
ATOM   7576  C CG2 . VAL B 1 475 ? 121.214 114.859 116.970 1.00 14.10  ? 475  VAL B CG2 1 
ATOM   7577  N N   . PHE B 1 476 ? 122.412 117.633 118.580 1.00 17.97  ? 476  PHE B N   1 
ATOM   7578  C CA  . PHE B 1 476 ? 123.443 118.280 119.372 1.00 17.97  ? 476  PHE B CA  1 
ATOM   7579  C C   . PHE B 1 476 ? 122.922 119.525 120.055 1.00 17.97  ? 476  PHE B C   1 
ATOM   7580  O O   . PHE B 1 476 ? 123.579 120.047 120.958 1.00 17.97  ? 476  PHE B O   1 
ATOM   7581  C CB  . PHE B 1 476 ? 124.632 118.677 118.510 1.00 17.97  ? 476  PHE B CB  1 
ATOM   7582  C CG  . PHE B 1 476 ? 125.630 117.595 118.296 1.00 17.97  ? 476  PHE B CG  1 
ATOM   7583  C CD1 . PHE B 1 476 ? 125.339 116.290 118.578 1.00 17.97  ? 476  PHE B CD1 1 
ATOM   7584  C CD2 . PHE B 1 476 ? 126.873 117.899 117.795 1.00 17.97  ? 476  PHE B CD2 1 
ATOM   7585  C CE1 . PHE B 1 476 ? 126.262 115.319 118.362 1.00 17.97  ? 476  PHE B CE1 1 
ATOM   7586  C CE2 . PHE B 1 476 ? 127.801 116.922 117.580 1.00 17.97  ? 476  PHE B CE2 1 
ATOM   7587  C CZ  . PHE B 1 476 ? 127.495 115.633 117.865 1.00 17.97  ? 476  PHE B CZ  1 
ATOM   7588  N N   . LEU B 1 477 ? 121.768 120.016 119.626 1.00 14.84  ? 477  LEU B N   1 
ATOM   7589  C CA  . LEU B 1 477 ? 121.115 121.165 120.221 1.00 14.84  ? 477  LEU B CA  1 
ATOM   7590  C C   . LEU B 1 477 ? 120.143 120.773 121.317 1.00 14.84  ? 477  LEU B C   1 
ATOM   7591  O O   . LEU B 1 477 ? 120.010 121.508 122.289 1.00 14.84  ? 477  LEU B O   1 
ATOM   7592  C CB  . LEU B 1 477 ? 120.383 121.963 119.142 1.00 14.84  ? 477  LEU B CB  1 
ATOM   7593  C CG  . LEU B 1 477 ? 119.868 123.343 119.506 1.00 14.84  ? 477  LEU B CG  1 
ATOM   7594  C CD1 . LEU B 1 477 ? 121.018 124.279 119.671 1.00 14.84  ? 477  LEU B CD1 1 
ATOM   7595  C CD2 . LEU B 1 477 ? 118.947 123.828 118.426 1.00 14.84  ? 477  LEU B CD2 1 
ATOM   7596  N N   . ILE B 1 478 ? 119.464 119.630 121.191 1.00 11.25  ? 478  ILE B N   1 
ATOM   7597  C CA  . ILE B 1 478 ? 118.604 119.161 122.272 1.00 11.25  ? 478  ILE B CA  1 
ATOM   7598  C C   . ILE B 1 478 ? 119.433 118.721 123.463 1.00 11.25  ? 478  ILE B C   1 
ATOM   7599  O O   . ILE B 1 478 ? 119.112 119.042 124.607 1.00 11.25  ? 478  ILE B O   1 
ATOM   7600  C CB  . ILE B 1 478 ? 117.704 118.012 121.806 1.00 11.25  ? 478  ILE B CB  1 
ATOM   7601  C CG1 . ILE B 1 478 ? 117.059 118.322 120.476 1.00 11.25  ? 478  ILE B CG1 1 
ATOM   7602  C CG2 . ILE B 1 478 ? 116.646 117.733 122.837 1.00 11.25  ? 478  ILE B CG2 1 
ATOM   7603  C CD1 . ILE B 1 478 ? 116.257 117.171 119.957 1.00 11.25  ? 478  ILE B CD1 1 
ATOM   7604  N N   . CYS B 1 479 ? 120.511 117.982 123.218 1.00 10.65  ? 479  CYS B N   1 
ATOM   7605  C CA  . CYS B 1 479 ? 121.249 117.352 124.298 1.00 10.65  ? 479  CYS B CA  1 
ATOM   7606  C C   . CYS B 1 479 ? 122.130 118.322 125.061 1.00 10.65  ? 479  CYS B C   1 
ATOM   7607  O O   . CYS B 1 479 ? 122.663 117.946 126.107 1.00 10.65  ? 479  CYS B O   1 
ATOM   7608  C CB  . CYS B 1 479 ? 122.104 116.216 123.759 1.00 10.65  ? 479  CYS B CB  1 
ATOM   7609  S SG  . CYS B 1 479 ? 123.585 116.749 122.948 1.00 10.65  ? 479  CYS B SG  1 
ATOM   7610  N N   . THR B 1 480 ? 122.294 119.546 124.568 1.00 7.36   ? 480  THR B N   1 
ATOM   7611  C CA  . THR B 1 480 ? 123.039 120.601 125.240 1.00 7.36   ? 480  THR B CA  1 
ATOM   7612  C C   . THR B 1 480 ? 122.156 121.672 125.850 1.00 7.36   ? 480  THR B C   1 
ATOM   7613  O O   . THR B 1 480 ? 122.426 122.113 126.963 1.00 7.36   ? 480  THR B O   1 
ATOM   7614  C CB  . THR B 1 480 ? 124.009 121.252 124.263 1.00 7.36   ? 480  THR B CB  1 
ATOM   7615  O OG1 . THR B 1 480 ? 123.298 121.609 123.078 1.00 7.36   ? 480  THR B OG1 1 
ATOM   7616  C CG2 . THR B 1 480 ? 125.116 120.311 123.914 1.00 7.36   ? 480  THR B CG2 1 
ATOM   7617  N N   . ALA B 1 481 ? 121.104 122.104 125.150 1.00 5.31   ? 481  ALA B N   1 
ATOM   7618  C CA  . ALA B 1 481 ? 120.172 123.077 125.705 1.00 5.31   ? 481  ALA B CA  1 
ATOM   7619  C C   . ALA B 1 481 ? 119.389 122.525 126.876 1.00 5.31   ? 481  ALA B C   1 
ATOM   7620  O O   . ALA B 1 481 ? 118.951 123.299 127.730 1.00 5.31   ? 481  ALA B O   1 
ATOM   7621  C CB  . ALA B 1 481 ? 119.188 123.552 124.644 1.00 5.31   ? 481  ALA B CB  1 
ATOM   7622  N N   . SER B 1 482 ? 119.199 121.214 126.939 1.00 8.79   ? 482  SER B N   1 
ATOM   7623  C CA  . SER B 1 482 ? 118.439 120.607 128.014 1.00 8.79   ? 482  SER B CA  1 
ATOM   7624  C C   . SER B 1 482 ? 119.301 119.937 129.057 1.00 8.79   ? 482  SER B C   1 
ATOM   7625  O O   . SER B 1 482 ? 118.757 119.334 129.977 1.00 8.79   ? 482  SER B O   1 
ATOM   7626  C CB  . SER B 1 482 ? 117.468 119.580 127.454 1.00 8.79   ? 482  SER B CB  1 
ATOM   7627  O OG  . SER B 1 482 ? 118.122 118.722 126.556 1.00 8.79   ? 482  SER B OG  1 
ATOM   7628  N N   . MET B 1 483 ? 120.618 119.999 128.923 1.00 13.13  ? 483  MET B N   1 
ATOM   7629  C CA  . MET B 1 483 ? 121.511 119.546 129.976 1.00 13.13  ? 483  MET B CA  1 
ATOM   7630  C C   . MET B 1 483 ? 122.102 120.708 130.757 1.00 13.13  ? 483  MET B C   1 
ATOM   7631  O O   . MET B 1 483 ? 122.527 120.523 131.901 1.00 13.13  ? 483  MET B O   1 
ATOM   7632  C CB  . MET B 1 483 ? 122.612 118.665 129.378 1.00 13.13  ? 483  MET B CB  1 
ATOM   7633  C CG  . MET B 1 483 ? 123.357 117.799 130.379 1.00 13.13  ? 483  MET B CG  1 
ATOM   7634  S SD  . MET B 1 483 ? 122.262 116.938 131.513 1.00 13.13  ? 483  MET B SD  1 
ATOM   7635  C CE  . MET B 1 483 ? 123.283 116.818 132.974 1.00 13.13  ? 483  MET B CE  1 
ATOM   7636  N N   . SER B 1 484 ? 122.113 121.906 130.177 1.00 10.27  ? 484  SER B N   1 
ATOM   7637  C CA  . SER B 1 484 ? 122.342 123.107 130.962 1.00 10.27  ? 484  SER B CA  1 
ATOM   7638  C C   . SER B 1 484 ? 121.092 123.548 131.702 1.00 10.27  ? 484  SER B C   1 
ATOM   7639  O O   . SER B 1 484 ? 121.195 124.322 132.655 1.00 10.27  ? 484  SER B O   1 
ATOM   7640  C CB  . SER B 1 484 ? 122.807 124.243 130.072 1.00 10.27  ? 484  SER B CB  1 
ATOM   7641  O OG  . SER B 1 484 ? 121.686 124.874 129.503 1.00 10.27  ? 484  SER B OG  1 
ATOM   7642  N N   . ALA B 1 485 ? 119.916 123.082 131.270 1.00 11.19  ? 485  ALA B N   1 
ATOM   7643  C CA  . ALA B 1 485 ? 118.680 123.351 131.994 1.00 11.19  ? 485  ALA B CA  1 
ATOM   7644  C C   . ALA B 1 485 ? 118.526 122.443 133.206 1.00 11.19  ? 485  ALA B C   1 
ATOM   7645  O O   . ALA B 1 485 ? 117.702 122.721 134.076 1.00 11.19  ? 485  ALA B O   1 
ATOM   7646  C CB  . ALA B 1 485 ? 117.479 123.204 131.064 1.00 11.19  ? 485  ALA B CB  1 
ATOM   7647  N N   . ILE B 1 486 ? 119.279 121.348 133.272 1.00 14.60  ? 486  ILE B N   1 
ATOM   7648  C CA  . ILE B 1 486 ? 119.317 120.539 134.486 1.00 14.60  ? 486  ILE B CA  1 
ATOM   7649  C C   . ILE B 1 486 ? 120.468 120.972 135.369 1.00 14.60  ? 486  ILE B C   1 
ATOM   7650  O O   . ILE B 1 486 ? 120.315 121.112 136.586 1.00 14.60  ? 486  ILE B O   1 
ATOM   7651  C CB  . ILE B 1 486 ? 119.415 119.048 134.138 1.00 14.60  ? 486  ILE B CB  1 
ATOM   7652  C CG1 . ILE B 1 486 ? 118.151 118.602 133.439 1.00 14.60  ? 486  ILE B CG1 1 
ATOM   7653  C CG2 . ILE B 1 486 ? 119.605 118.213 135.370 1.00 14.60  ? 486  ILE B CG2 1 
ATOM   7654  C CD1 . ILE B 1 486 ? 118.365 117.430 132.561 1.00 14.60  ? 486  ILE B CD1 1 
ATOM   7655  N N   . ALA B 1 487 ? 121.628 121.239 134.766 1.00 14.48  ? 487  ALA B N   1 
ATOM   7656  C CA  . ALA B 1 487 ? 122.780 121.700 135.530 1.00 14.48  ? 487  ALA B CA  1 
ATOM   7657  C C   . ALA B 1 487 ? 122.587 123.101 136.092 1.00 14.48  ? 487  ALA B C   1 
ATOM   7658  O O   . ALA B 1 487 ? 123.361 123.513 136.957 1.00 14.48  ? 487  ALA B O   1 
ATOM   7659  C CB  . ALA B 1 487 ? 124.036 121.660 134.672 1.00 14.48  ? 487  ALA B CB  1 
ATOM   7660  N N   . GLY B 1 488 ? 121.580 123.835 135.624 1.00 16.23  ? 488  GLY B N   1 
ATOM   7661  C CA  . GLY B 1 488 ? 121.143 125.053 136.273 1.00 16.23  ? 488  GLY B CA  1 
ATOM   7662  C C   . GLY B 1 488 ? 120.219 124.789 137.441 1.00 16.23  ? 488  GLY B C   1 
ATOM   7663  O O   . GLY B 1 488 ? 120.479 125.259 138.549 1.00 16.23  ? 488  GLY B O   1 
ATOM   7664  N N   . VAL B 1 489 ? 119.141 124.032 137.209 1.00 15.14  ? 489  VAL B N   1 
ATOM   7665  C CA  . VAL B 1 489 ? 118.152 123.768 138.253 1.00 15.14  ? 489  VAL B CA  1 
ATOM   7666  C C   . VAL B 1 489 ? 118.734 122.869 139.344 1.00 15.14  ? 489  VAL B C   1 
ATOM   7667  O O   . VAL B 1 489 ? 118.356 122.974 140.515 1.00 15.14  ? 489  VAL B O   1 
ATOM   7668  C CB  . VAL B 1 489 ? 116.879 123.201 137.596 1.00 15.14  ? 489  VAL B CB  1 
ATOM   7669  C CG1 . VAL B 1 489 ? 115.813 122.859 138.598 1.00 15.14  ? 489  VAL B CG1 1 
ATOM   7670  C CG2 . VAL B 1 489 ? 116.324 124.217 136.640 1.00 15.14  ? 489  VAL B CG2 1 
ATOM   7671  N N   . MET B 1 490 ? 119.721 122.037 139.009 1.00 16.97  ? 490  MET B N   1 
ATOM   7672  C CA  . MET B 1 490 ? 120.534 121.379 140.024 1.00 16.97  ? 490  MET B CA  1 
ATOM   7673  C C   . MET B 1 490 ? 121.784 122.170 140.364 1.00 16.97  ? 490  MET B C   1 
ATOM   7674  O O   . MET B 1 490 ? 122.813 121.581 140.709 1.00 16.97  ? 490  MET B O   1 
ATOM   7675  C CB  . MET B 1 490 ? 120.913 119.961 139.600 1.00 16.97  ? 490  MET B CB  1 
ATOM   7676  C CG  . MET B 1 490 ? 119.755 119.046 139.237 1.00 16.97  ? 490  MET B CG  1 
ATOM   7677  S SD  . MET B 1 490 ? 118.231 119.351 140.139 1.00 16.97  ? 490  MET B SD  1 
ATOM   7678  C CE  . MET B 1 490 ? 118.665 118.754 141.762 1.00 16.97  ? 490  MET B CE  1 
ATOM   7679  N N   . PHE B 1 491 ? 121.733 123.492 140.228 1.00 23.14  ? 491  PHE B N   1 
ATOM   7680  C CA  . PHE B 1 491 ? 122.664 124.390 140.894 1.00 23.14  ? 491  PHE B CA  1 
ATOM   7681  C C   . PHE B 1 491 ? 121.963 125.374 141.814 1.00 23.14  ? 491  PHE B C   1 
ATOM   7682  O O   . PHE B 1 491 ? 122.499 125.700 142.872 1.00 23.14  ? 491  PHE B O   1 
ATOM   7683  C CB  . PHE B 1 491 ? 123.501 125.155 139.864 1.00 23.14  ? 491  PHE B CB  1 
ATOM   7684  C CG  . PHE B 1 491 ? 124.349 126.233 140.455 1.00 23.14  ? 491  PHE B CG  1 
ATOM   7685  C CD1 . PHE B 1 491 ? 125.307 125.936 141.406 1.00 23.14  ? 491  PHE B CD1 1 
ATOM   7686  C CD2 . PHE B 1 491 ? 124.189 127.543 140.057 1.00 23.14  ? 491  PHE B CD2 1 
ATOM   7687  C CE1 . PHE B 1 491 ? 126.076 126.929 141.957 1.00 23.14  ? 491  PHE B CE1 1 
ATOM   7688  C CE2 . PHE B 1 491 ? 124.961 128.532 140.594 1.00 23.14  ? 491  PHE B CE2 1 
ATOM   7689  C CZ  . PHE B 1 491 ? 125.909 128.223 141.547 1.00 23.14  ? 491  PHE B CZ  1 
ATOM   7690  N N   . VAL B 1 492 ? 120.747 125.809 141.463 1.00 22.21  ? 492  VAL B N   1 
ATOM   7691  C CA  . VAL B 1 492 ? 119.910 126.571 142.384 1.00 22.21  ? 492  VAL B CA  1 
ATOM   7692  C C   . VAL B 1 492 ? 119.342 125.707 143.501 1.00 22.21  ? 492  VAL B C   1 
ATOM   7693  O O   . VAL B 1 492 ? 118.781 126.245 144.463 1.00 22.21  ? 492  VAL B O   1 
ATOM   7694  C CB  . VAL B 1 492 ? 118.751 127.269 141.641 1.00 22.21  ? 492  VAL B CB  1 
ATOM   7695  C CG1 . VAL B 1 492 ? 119.252 127.910 140.368 1.00 22.21  ? 492  VAL B CG1 1 
ATOM   7696  C CG2 . VAL B 1 492 ? 117.620 126.303 141.347 1.00 22.21  ? 492  VAL B CG2 1 
ATOM   7697  N N   . HIS B 1 493 ? 119.469 124.386 143.404 1.00 28.91  ? 493  HIS B N   1 
ATOM   7698  C CA  . HIS B 1 493 ? 119.001 123.449 144.410 1.00 28.91  ? 493  HIS B CA  1 
ATOM   7699  C C   . HIS B 1 493 ? 120.115 122.999 145.345 1.00 28.91  ? 493  HIS B C   1 
ATOM   7700  O O   . HIS B 1 493 ? 119.826 122.479 146.425 1.00 28.91  ? 493  HIS B O   1 
ATOM   7701  C CB  . HIS B 1 493 ? 118.361 122.243 143.709 1.00 28.91  ? 493  HIS B CB  1 
ATOM   7702  C CG  . HIS B 1 493 ? 117.712 121.258 144.627 1.00 28.91  ? 493  HIS B CG  1 
ATOM   7703  N ND1 . HIS B 1 493 ? 118.429 120.324 145.342 1.00 28.91  ? 493  HIS B ND1 1 
ATOM   7704  C CD2 . HIS B 1 493 ? 116.410 121.036 144.917 1.00 28.91  ? 493  HIS B CD2 1 
ATOM   7705  C CE1 . HIS B 1 493 ? 117.597 119.580 146.046 1.00 28.91  ? 493  HIS B CE1 1 
ATOM   7706  N NE2 . HIS B 1 493 ? 116.366 119.990 145.805 1.00 28.91  ? 493  HIS B NE2 1 
ATOM   7707  N N   . LEU B 1 494 ? 121.375 123.181 144.967 1.00 29.78  ? 494  LEU B N   1 
ATOM   7708  C CA  . LEU B 1 494 ? 122.468 123.011 145.908 1.00 29.78  ? 494  LEU B CA  1 
ATOM   7709  C C   . LEU B 1 494 ? 122.582 124.193 146.861 1.00 29.78  ? 494  LEU B C   1 
ATOM   7710  O O   . LEU B 1 494 ? 122.828 123.994 148.056 1.00 29.78  ? 494  LEU B O   1 
ATOM   7711  C CB  . LEU B 1 494 ? 123.789 122.815 145.169 1.00 29.78  ? 494  LEU B CB  1 
ATOM   7712  C CG  . LEU B 1 494 ? 124.980 122.473 146.069 1.00 29.78  ? 494  LEU B CG  1 
ATOM   7713  C CD1 . LEU B 1 494 ? 124.847 121.079 146.646 1.00 29.78  ? 494  LEU B CD1 1 
ATOM   7714  C CD2 . LEU B 1 494 ? 126.290 122.631 145.354 1.00 29.78  ? 494  LEU B CD2 1 
ATOM   7715  N N   . SER B 1 495 ? 122.384 125.414 146.358 1.00 35.14  ? 495  SER B N   1 
ATOM   7716  C CA  . SER B 1 495 ? 122.445 126.643 147.139 1.00 35.14  ? 495  SER B CA  1 
ATOM   7717  C C   . SER B 1 495 ? 121.419 126.671 148.254 1.00 35.14  ? 495  SER B C   1 
ATOM   7718  O O   . SER B 1 495 ? 121.756 126.996 149.394 1.00 35.14  ? 495  SER B O   1 
ATOM   7719  C CB  . SER B 1 495 ? 122.219 127.861 146.240 1.00 35.14  ? 495  SER B CB  1 
ATOM   7720  O OG  . SER B 1 495 ? 120.832 128.051 146.029 1.00 35.14  ? 495  SER B OG  1 
ATOM   7721  N N   . LEU B 1 496 ? 120.172 126.316 147.941 1.00 36.32  ? 496  LEU B N   1 
ATOM   7722  C CA  . LEU B 1 496 ? 119.128 126.234 148.950 1.00 36.32  ? 496  LEU B CA  1 
ATOM   7723  C C   . LEU B 1 496 ? 119.434 125.178 150.003 1.00 36.32  ? 496  LEU B C   1 
ATOM   7724  O O   . LEU B 1 496 ? 119.012 125.331 151.152 1.00 36.32  ? 496  LEU B O   1 
ATOM   7725  C CB  . LEU B 1 496 ? 117.779 125.948 148.282 1.00 36.32  ? 496  LEU B CB  1 
ATOM   7726  C CG  . LEU B 1 496 ? 117.284 127.018 147.304 1.00 36.32  ? 496  LEU B CG  1 
ATOM   7727  C CD1 . LEU B 1 496 ? 116.021 126.593 146.616 1.00 36.32  ? 496  LEU B CD1 1 
ATOM   7728  C CD2 . LEU B 1 496 ? 117.051 128.316 148.006 1.00 36.32  ? 496  LEU B CD2 1 
ATOM   7729  N N   . LEU B 1 497 ? 120.192 124.138 149.652 1.00 40.87  ? 497  LEU B N   1 
ATOM   7730  C CA  . LEU B 1 497 ? 120.617 123.125 150.607 1.00 40.87  ? 497  LEU B CA  1 
ATOM   7731  C C   . LEU B 1 497 ? 122.053 123.355 151.065 1.00 40.87  ? 497  LEU B C   1 
ATOM   7732  O O   . LEU B 1 497 ? 122.725 122.428 151.522 1.00 40.87  ? 497  LEU B O   1 
ATOM   7733  C CB  . LEU B 1 497 ? 120.454 121.724 150.026 1.00 40.87  ? 497  LEU B CB  1 
ATOM   7734  C CG  . LEU B 1 497 ? 119.008 121.321 149.760 1.00 40.87  ? 497  LEU B CG  1 
ATOM   7735  C CD1 . LEU B 1 497 ? 118.962 119.894 149.281 1.00 40.87  ? 497  LEU B CD1 1 
ATOM   7736  C CD2 . LEU B 1 497 ? 118.158 121.500 150.998 1.00 40.87  ? 497  LEU B CD2 1 
ATOM   7737  N N   . GLU B 1 498 ? 122.537 124.587 150.944 1.00 52.72  ? 498  GLU B N   1 
ATOM   7738  C CA  . GLU B 1 498 ? 123.728 124.984 151.681 1.00 52.72  ? 498  GLU B CA  1 
ATOM   7739  C C   . GLU B 1 498 ? 123.357 125.692 152.978 1.00 52.72  ? 498  GLU B C   1 
ATOM   7740  O O   . GLU B 1 498 ? 124.037 125.528 153.997 1.00 52.72  ? 498  GLU B O   1 
ATOM   7741  C CB  . GLU B 1 498 ? 124.612 125.888 150.818 1.00 52.72  ? 498  GLU B CB  1 
ATOM   7742  C CG  . GLU B 1 498 ? 125.998 126.163 151.384 1.00 52.72  ? 498  GLU B CG  1 
ATOM   7743  C CD  . GLU B 1 498 ? 126.961 126.664 150.327 1.00 52.72  ? 498  GLU B CD  1 
ATOM   7744  O OE1 . GLU B 1 498 ? 126.685 127.720 149.722 1.00 52.72  ? 498  GLU B OE1 1 
ATOM   7745  O OE2 . GLU B 1 498 ? 127.990 126.002 150.090 1.00 52.72  ? 498  GLU B OE2 1 
ATOM   7746  N N   . LYS B 1 499 ? 122.270 126.462 152.956 1.00 43.26  ? 499  LYS B N   1 
ATOM   7747  C CA  . LYS B 1 499 ? 121.773 127.185 154.118 1.00 43.26  ? 499  LYS B CA  1 
ATOM   7748  C C   . LYS B 1 499 ? 120.501 126.583 154.700 1.00 43.26  ? 499  LYS B C   1 
ATOM   7749  O O   . LYS B 1 499 ? 120.202 126.809 155.875 1.00 43.26  ? 499  LYS B O   1 
ATOM   7750  C CB  . LYS B 1 499 ? 121.525 128.651 153.750 1.00 43.26  ? 499  LYS B CB  1 
ATOM   7751  C CG  . LYS B 1 499 ? 120.394 128.873 152.757 1.00 43.26  ? 499  LYS B CG  1 
ATOM   7752  C CD  . LYS B 1 499 ? 120.251 130.338 152.394 1.00 43.26  ? 499  LYS B CD  1 
ATOM   7753  C CE  . LYS B 1 499 ? 118.844 130.655 151.923 1.00 43.26  ? 499  LYS B CE  1 
ATOM   7754  N NZ  . LYS B 1 499 ? 118.480 129.884 150.717 1.00 43.26  ? 499  LYS B NZ  1 
ATOM   7755  N N   . GLY B 1 500 ? 119.744 125.821 153.913 1.00 46.89  ? 500  GLY B N   1 
ATOM   7756  C CA  . GLY B 1 500 ? 118.482 125.277 154.377 1.00 46.89  ? 500  GLY B CA  1 
ATOM   7757  C C   . GLY B 1 500 ? 117.324 126.204 154.077 1.00 46.89  ? 500  GLY B C   1 
ATOM   7758  O O   . GLY B 1 500 ? 117.294 127.342 154.551 1.00 46.89  ? 500  GLY B O   1 
ATOM   7759  N N   . TYR B 1 501 ? 116.377 125.746 153.269 1.00 47.70  ? 501  TYR B N   1 
ATOM   7760  C CA  . TYR B 1 501 ? 115.207 126.539 152.898 1.00 47.70  ? 501  TYR B CA  1 
ATOM   7761  C C   . TYR B 1 501 ? 113.949 125.667 152.933 1.00 47.70  ? 501  TYR B C   1 
ATOM   7762  O O   . TYR B 1 501 ? 113.296 125.447 151.910 1.00 47.70  ? 501  TYR B O   1 
ATOM   7763  C CB  . TYR B 1 501 ? 115.392 127.235 151.549 1.00 47.70  ? 501  TYR B CB  1 
ATOM   7764  C CG  . TYR B 1 501 ? 114.284 128.222 151.216 1.00 47.70  ? 501  TYR B CG  1 
ATOM   7765  C CD1 . TYR B 1 501 ? 113.739 129.042 152.198 1.00 47.70  ? 501  TYR B CD1 1 
ATOM   7766  C CD2 . TYR B 1 501 ? 113.771 128.316 149.927 1.00 47.70  ? 501  TYR B CD2 1 
ATOM   7767  C CE1 . TYR B 1 501 ? 112.720 129.934 151.902 1.00 47.70  ? 501  TYR B CE1 1 
ATOM   7768  C CE2 . TYR B 1 501 ? 112.754 129.206 149.622 1.00 47.70  ? 501  TYR B CE2 1 
ATOM   7769  C CZ  . TYR B 1 501 ? 112.235 130.011 150.613 1.00 47.70  ? 501  TYR B CZ  1 
ATOM   7770  O OH  . TYR B 1 501 ? 111.228 130.895 150.314 1.00 47.70  ? 501  TYR B OH  1 
ATOM   7771  N N   . SER B 1 502 ? 113.666 125.085 154.109 1.00 52.25  ? 502  SER B N   1 
ATOM   7772  C CA  . SER B 1 502 ? 112.418 124.370 154.396 1.00 52.25  ? 502  SER B CA  1 
ATOM   7773  C C   . SER B 1 502 ? 112.229 123.122 153.543 1.00 52.25  ? 502  SER B C   1 
ATOM   7774  O O   . SER B 1 502 ? 111.448 123.139 152.585 1.00 52.25  ? 502  SER B O   1 
ATOM   7775  C CB  . SER B 1 502 ? 111.196 125.293 154.249 1.00 52.25  ? 502  SER B CB  1 
ATOM   7776  O OG  . SER B 1 502 ? 110.794 125.400 152.892 1.00 52.25  ? 502  SER B OG  1 
ATOM   7777  N N   . PHE B 1 503 ? 112.983 122.066 153.876 1.00 53.46  ? 503  PHE B N   1 
ATOM   7778  C CA  . PHE B 1 503 ? 113.080 120.768 153.203 1.00 53.46  ? 503  PHE B CA  1 
ATOM   7779  C C   . PHE B 1 503 ? 111.793 120.177 152.634 1.00 53.46  ? 503  PHE B C   1 
ATOM   7780  O O   . PHE B 1 503 ? 111.833 119.479 151.616 1.00 53.46  ? 503  PHE B O   1 
ATOM   7781  C CB  . PHE B 1 503 ? 113.659 119.748 154.178 1.00 53.46  ? 503  PHE B CB  1 
ATOM   7782  C CG  . PHE B 1 503 ? 115.131 119.524 154.028 1.00 53.46  ? 503  PHE B CG  1 
ATOM   7783  C CD1 . PHE B 1 503 ? 116.039 120.465 154.486 1.00 53.46  ? 503  PHE B CD1 1 
ATOM   7784  C CD2 . PHE B 1 503 ? 115.609 118.363 153.444 1.00 53.46  ? 503  PHE B CD2 1 
ATOM   7785  C CE1 . PHE B 1 503 ? 117.400 120.257 154.354 1.00 53.46  ? 503  PHE B CE1 1 
ATOM   7786  C CE2 . PHE B 1 503 ? 116.965 118.150 153.309 1.00 53.46  ? 503  PHE B CE2 1 
ATOM   7787  C CZ  . PHE B 1 503 ? 117.862 119.099 153.765 1.00 53.46  ? 503  PHE B CZ  1 
ATOM   7788  N N   . ARG B 1 504 ? 110.655 120.433 153.287 1.00 68.76  ? 504  ARG B N   1 
ATOM   7789  C CA  . ARG B 1 504 ? 109.364 119.928 152.836 1.00 68.76  ? 504  ARG B CA  1 
ATOM   7790  C C   . ARG B 1 504 ? 108.933 120.481 151.481 1.00 68.76  ? 504  ARG B C   1 
ATOM   7791  O O   . ARG B 1 504 ? 108.090 119.862 150.825 1.00 68.76  ? 504  ARG B O   1 
ATOM   7792  C CB  . ARG B 1 504 ? 108.292 120.240 153.883 1.00 68.76  ? 504  ARG B CB  1 
ATOM   7793  C CG  . ARG B 1 504 ? 107.136 119.247 153.917 1.00 68.76  ? 504  ARG B CG  1 
ATOM   7794  C CD  . ARG B 1 504 ? 105.786 119.954 153.900 1.00 68.76  ? 504  ARG B CD  1 
ATOM   7795  N NE  . ARG B 1 504 ? 105.511 120.605 152.621 1.00 68.76  ? 504  ARG B NE  1 
ATOM   7796  C CZ  . ARG B 1 504 ? 104.988 119.996 151.562 1.00 68.76  ? 504  ARG B CZ  1 
ATOM   7797  N NH1 . ARG B 1 504 ? 104.674 118.710 151.620 1.00 68.76  ? 504  ARG B NH1 1 
ATOM   7798  N NH2 . ARG B 1 504 ? 104.776 120.674 150.443 1.00 68.76  ? 504  ARG B NH2 1 
ATOM   7799  N N   . GLN B 1 505 ? 109.475 121.611 151.043 1.00 62.60  ? 505  GLN B N   1 
ATOM   7800  C CA  . GLN B 1 505 ? 109.101 122.166 149.751 1.00 62.60  ? 505  GLN B CA  1 
ATOM   7801  C C   . GLN B 1 505 ? 110.269 122.345 148.793 1.00 62.60  ? 505  GLN B C   1 
ATOM   7802  O O   . GLN B 1 505 ? 110.036 122.587 147.608 1.00 62.60  ? 505  GLN B O   1 
ATOM   7803  C CB  . GLN B 1 505 ? 108.396 123.519 149.934 1.00 62.60  ? 505  GLN B CB  1 
ATOM   7804  C CG  . GLN B 1 505 ? 107.178 123.708 149.042 1.00 62.60  ? 505  GLN B CG  1 
ATOM   7805  C CD  . GLN B 1 505 ? 107.495 124.411 147.741 1.00 62.60  ? 505  GLN B CD  1 
ATOM   7806  O OE1 . GLN B 1 505 ? 108.432 125.202 147.661 1.00 62.60  ? 505  GLN B OE1 1 
ATOM   7807  N NE2 . GLN B 1 505 ? 106.711 124.126 146.710 1.00 62.60  ? 505  GLN B NE2 1 
ATOM   7808  N N   . VAL B 1 506 ? 111.514 122.235 149.261 1.00 52.84  ? 506  VAL B N   1 
ATOM   7809  C CA  . VAL B 1 506 ? 112.636 122.345 148.335 1.00 52.84  ? 506  VAL B CA  1 
ATOM   7810  C C   . VAL B 1 506 ? 112.839 121.024 147.598 1.00 52.84  ? 506  VAL B C   1 
ATOM   7811  O O   . VAL B 1 506 ? 113.404 120.990 146.499 1.00 52.84  ? 506  VAL B O   1 
ATOM   7812  C CB  . VAL B 1 506 ? 113.908 122.816 149.080 1.00 52.84  ? 506  VAL B CB  1 
ATOM   7813  C CG1 . VAL B 1 506 ? 114.496 121.726 149.945 1.00 52.84  ? 506  VAL B CG1 1 
ATOM   7814  C CG2 . VAL B 1 506 ? 114.952 123.373 148.127 1.00 52.84  ? 506  VAL B CG2 1 
ATOM   7815  N N   . GLN B 1 507 ? 112.348 119.919 148.167 1.00 52.65  ? 507  GLN B N   1 
ATOM   7816  C CA  . GLN B 1 507 ? 112.492 118.598 147.555 1.00 52.65  ? 507  GLN B CA  1 
ATOM   7817  C C   . GLN B 1 507 ? 111.247 118.219 146.749 1.00 52.65  ? 507  GLN B C   1 
ATOM   7818  O O   . GLN B 1 507 ? 110.635 117.168 146.930 1.00 52.65  ? 507  GLN B O   1 
ATOM   7819  C CB  . GLN B 1 507 ? 112.817 117.566 148.622 1.00 52.65  ? 507  GLN B CB  1 
ATOM   7820  C CG  . GLN B 1 507 ? 114.305 117.459 148.869 1.00 52.65  ? 507  GLN B CG  1 
ATOM   7821  C CD  . GLN B 1 507 ? 114.659 116.373 149.849 1.00 52.65  ? 507  GLN B CD  1 
ATOM   7822  O OE1 . GLN B 1 507 ? 115.745 116.382 150.429 1.00 52.65  ? 507  GLN B OE1 1 
ATOM   7823  N NE2 . GLN B 1 507 ? 113.741 115.441 150.061 1.00 52.65  ? 507  GLN B NE2 1 
ATOM   7824  N N   . VAL B 1 508 ? 110.876 119.130 145.857 1.00 46.91  ? 508  VAL B N   1 
ATOM   7825  C CA  . VAL B 1 508 ? 110.015 118.819 144.719 1.00 46.91  ? 508  VAL B CA  1 
ATOM   7826  C C   . VAL B 1 508 ? 110.670 119.193 143.401 1.00 46.91  ? 508  VAL B C   1 
ATOM   7827  O O   . VAL B 1 508 ? 110.468 118.491 142.390 1.00 46.91  ? 508  VAL B O   1 
ATOM   7828  C CB  . VAL B 1 508 ? 108.644 119.524 144.894 1.00 46.91  ? 508  VAL B CB  1 
ATOM   7829  C CG1 . VAL B 1 508 ? 107.812 119.615 143.616 1.00 46.91  ? 508  VAL B CG1 1 
ATOM   7830  C CG2 . VAL B 1 508 ? 107.837 118.809 145.963 1.00 46.91  ? 508  VAL B CG2 1 
ATOM   7831  N N   . ILE B 1 509 ? 111.548 120.193 143.418 1.00 42.26  ? 509  ILE B N   1 
ATOM   7832  C CA  . ILE B 1 509 ? 112.496 120.589 142.374 1.00 42.26  ? 509  ILE B CA  1 
ATOM   7833  C C   . ILE B 1 509 ? 113.223 119.409 141.711 1.00 42.26  ? 509  ILE B C   1 
ATOM   7834  O O   . ILE B 1 509 ? 113.366 119.434 140.478 1.00 42.26  ? 509  ILE B O   1 
ATOM   7835  C CB  . ILE B 1 509 ? 113.478 121.628 142.958 1.00 42.26  ? 509  ILE B CB  1 
ATOM   7836  C CG1 . ILE B 1 509 ? 112.726 122.884 143.404 1.00 42.26  ? 509  ILE B CG1 1 
ATOM   7837  C CG2 . ILE B 1 509 ? 114.581 121.997 141.996 1.00 42.26  ? 509  ILE B CG2 1 
ATOM   7838  C CD1 . ILE B 1 509 ? 112.293 123.798 142.270 1.00 42.26  ? 509  ILE B CD1 1 
ATOM   7839  N N   . PRO B 1 510 ? 113.685 118.352 142.418 1.00 38.24  ? 510  PRO B N   1 
ATOM   7840  C CA  . PRO B 1 510 ? 114.100 117.149 141.664 1.00 38.24  ? 510  PRO B CA  1 
ATOM   7841  C C   . PRO B 1 510 ? 112.958 116.471 140.932 1.00 38.24  ? 510  PRO B C   1 
ATOM   7842  O O   . PRO B 1 510 ? 113.008 116.334 139.707 1.00 38.24  ? 510  PRO B O   1 
ATOM   7843  C CB  . PRO B 1 510 ? 114.693 116.240 142.746 1.00 38.24  ? 510  PRO B CB  1 
ATOM   7844  C CG  . PRO B 1 510 ? 115.105 117.142 143.806 1.00 38.24  ? 510  PRO B CG  1 
ATOM   7845  C CD  . PRO B 1 510 ? 114.057 118.196 143.843 1.00 38.24  ? 510  PRO B CD  1 
ATOM   7846  N N   . GLY B 1 511 ? 111.903 116.092 141.640 1.00 36.59  ? 511  GLY B N   1 
ATOM   7847  C CA  . GLY B 1 511 ? 110.780 115.401 141.047 1.00 36.59  ? 511  GLY B CA  1 
ATOM   7848  C C   . GLY B 1 511 ? 109.897 116.213 140.128 1.00 36.59  ? 511  GLY B C   1 
ATOM   7849  O O   . GLY B 1 511 ? 108.940 115.669 139.575 1.00 36.59  ? 511  GLY B O   1 
ATOM   7850  N N   . LEU B 1 512 ? 110.178 117.504 139.951 1.00 37.33  ? 512  LEU B N   1 
ATOM   7851  C CA  . LEU B 1 512 ? 109.454 118.348 139.013 1.00 37.33  ? 512  LEU B CA  1 
ATOM   7852  C C   . LEU B 1 512 ? 110.233 118.595 137.733 1.00 37.33  ? 512  LEU B C   1 
ATOM   7853  O O   . LEU B 1 512 ? 109.621 118.754 136.673 1.00 37.33  ? 512  LEU B O   1 
ATOM   7854  C CB  . LEU B 1 512 ? 109.120 119.698 139.666 1.00 37.33  ? 512  LEU B CB  1 
ATOM   7855  C CG  . LEU B 1 512 ? 108.196 120.680 138.954 1.00 37.33  ? 512  LEU B CG  1 
ATOM   7856  C CD1 . LEU B 1 512 ? 106.804 120.092 138.860 1.00 37.33  ? 512  LEU B CD1 1 
ATOM   7857  C CD2 . LEU B 1 512 ? 108.176 122.007 139.680 1.00 37.33  ? 512  LEU B CD2 1 
ATOM   7858  N N   . LEU B 1 513 ? 111.565 118.634 137.818 1.00 29.74  ? 513  LEU B N   1 
ATOM   7859  C CA  . LEU B 1 513 ? 112.410 118.673 136.633 1.00 29.74  ? 513  LEU B CA  1 
ATOM   7860  C C   . LEU B 1 513 ? 112.222 117.428 135.788 1.00 29.74  ? 513  LEU B C   1 
ATOM   7861  O O   . LEU B 1 513 ? 112.264 117.501 134.557 1.00 29.74  ? 513  LEU B O   1 
ATOM   7862  C CB  . LEU B 1 513 ? 113.866 118.821 137.058 1.00 29.74  ? 513  LEU B CB  1 
ATOM   7863  C CG  . LEU B 1 513 ? 114.950 118.860 136.000 1.00 29.74  ? 513  LEU B CG  1 
ATOM   7864  C CD1 . LEU B 1 513 ? 114.632 119.898 134.956 1.00 29.74  ? 513  LEU B CD1 1 
ATOM   7865  C CD2 . LEU B 1 513 ? 116.245 119.170 136.689 1.00 29.74  ? 513  LEU B CD2 1 
ATOM   7866  N N   . LEU B 1 514 ? 112.023 116.284 136.439 1.00 29.38  ? 514  LEU B N   1 
ATOM   7867  C CA  . LEU B 1 514 ? 111.549 115.095 135.749 1.00 29.38  ? 514  LEU B CA  1 
ATOM   7868  C C   . LEU B 1 514 ? 110.180 115.341 135.133 1.00 29.38  ? 514  LEU B C   1 
ATOM   7869  O O   . LEU B 1 514 ? 109.939 114.994 133.971 1.00 29.38  ? 514  LEU B O   1 
ATOM   7870  C CB  . LEU B 1 514 ? 111.505 113.928 136.732 1.00 29.38  ? 514  LEU B CB  1 
ATOM   7871  C CG  . LEU B 1 514 ? 111.086 112.543 136.263 1.00 29.38  ? 514  LEU B CG  1 
ATOM   7872  C CD1 . LEU B 1 514 ? 111.966 111.582 136.947 1.00 29.38  ? 514  LEU B CD1 1 
ATOM   7873  C CD2 . LEU B 1 514 ? 109.647 112.224 136.633 1.00 29.38  ? 514  LEU B CD2 1 
ATOM   7874  N N   . LEU B 1 515 ? 109.275 115.957 135.898 1.00 36.44  ? 515  LEU B N   1 
ATOM   7875  C CA  . LEU B 1 515 ? 107.924 116.199 135.414 1.00 36.44  ? 515  LEU B CA  1 
ATOM   7876  C C   . LEU B 1 515 ? 107.889 117.257 134.327 1.00 36.44  ? 515  LEU B C   1 
ATOM   7877  O O   . LEU B 1 515 ? 107.031 117.188 133.446 1.00 36.44  ? 515  LEU B O   1 
ATOM   7878  C CB  . LEU B 1 515 ? 107.014 116.602 136.575 1.00 36.44  ? 515  LEU B CB  1 
ATOM   7879  C CG  . LEU B 1 515 ? 105.513 116.702 136.287 1.00 36.44  ? 515  LEU B CG  1 
ATOM   7880  C CD1 . LEU B 1 515 ? 105.002 115.430 135.634 1.00 36.44  ? 515  LEU B CD1 1 
ATOM   7881  C CD2 . LEU B 1 515 ? 104.742 117.005 137.551 1.00 36.44  ? 515  LEU B CD2 1 
ATOM   7882  N N   . GLY B 1 516 ? 108.809 118.216 134.354 1.00 35.20  ? 516  GLY B N   1 
ATOM   7883  C CA  . GLY B 1 516 ? 108.914 119.171 133.268 1.00 35.20  ? 516  GLY B CA  1 
ATOM   7884  C C   . GLY B 1 516 ? 109.365 118.515 131.979 1.00 35.20  ? 516  GLY B C   1 
ATOM   7885  O O   . GLY B 1 516 ? 108.808 118.770 130.910 1.00 35.20  ? 516  GLY B O   1 
ATOM   7886  N N   . PHE B 1 517 ? 110.366 117.639 132.086 1.00 26.01  ? 517  PHE B N   1 
ATOM   7887  C CA  . PHE B 1 517 ? 110.877 116.929 130.924 1.00 26.01  ? 517  PHE B CA  1 
ATOM   7888  C C   . PHE B 1 517 ? 109.924 115.859 130.431 1.00 26.01  ? 517  PHE B C   1 
ATOM   7889  O O   . PHE B 1 517 ? 109.989 115.488 129.257 1.00 26.01  ? 517  PHE B O   1 
ATOM   7890  C CB  . PHE B 1 517 ? 112.221 116.299 131.249 1.00 26.01  ? 517  PHE B CB  1 
ATOM   7891  C CG  . PHE B 1 517 ? 113.372 117.164 130.907 1.00 26.01  ? 517  PHE B CG  1 
ATOM   7892  C CD1 . PHE B 1 517 ? 113.757 117.325 129.598 1.00 26.01  ? 517  PHE B CD1 1 
ATOM   7893  C CD2 . PHE B 1 517 ? 114.060 117.835 131.889 1.00 26.01  ? 517  PHE B CD2 1 
ATOM   7894  C CE1 . PHE B 1 517 ? 114.811 118.130 129.283 1.00 26.01  ? 517  PHE B CE1 1 
ATOM   7895  C CE2 . PHE B 1 517 ? 115.112 118.640 131.574 1.00 26.01  ? 517  PHE B CE2 1 
ATOM   7896  C CZ  . PHE B 1 517 ? 115.492 118.784 130.278 1.00 26.01  ? 517  PHE B CZ  1 
ATOM   7897  N N   . LEU B 1 518 ? 109.054 115.348 131.296 1.00 31.26  ? 518  LEU B N   1 
ATOM   7898  C CA  . LEU B 1 518 ? 108.119 114.319 130.866 1.00 31.26  ? 518  LEU B CA  1 
ATOM   7899  C C   . LEU B 1 518 ? 107.053 114.895 129.945 1.00 31.26  ? 518  LEU B C   1 
ATOM   7900  O O   . LEU B 1 518 ? 106.625 114.225 129.000 1.00 31.26  ? 518  LEU B O   1 
ATOM   7901  C CB  . LEU B 1 518 ? 107.488 113.668 132.094 1.00 31.26  ? 518  LEU B CB  1 
ATOM   7902  C CG  . LEU B 1 518 ? 107.031 112.210 132.067 1.00 31.26  ? 518  LEU B CG  1 
ATOM   7903  C CD1 . LEU B 1 518 ? 106.950 111.708 133.494 1.00 31.26  ? 518  LEU B CD1 1 
ATOM   7904  C CD2 . LEU B 1 518 ? 105.695 112.021 131.373 1.00 31.26  ? 518  LEU B CD2 1 
ATOM   7905  N N   . LEU B 1 519 ? 106.631 116.135 130.192 1.00 35.87  ? 519  LEU B N   1 
ATOM   7906  C CA  . LEU B 1 519 ? 105.574 116.764 129.412 1.00 35.87  ? 519  LEU B CA  1 
ATOM   7907  C C   . LEU B 1 519 ? 106.074 117.447 128.152 1.00 35.87  ? 519  LEU B C   1 
ATOM   7908  O O   . LEU B 1 519 ? 105.283 117.644 127.227 1.00 35.87  ? 519  LEU B O   1 
ATOM   7909  C CB  . LEU B 1 519 ? 104.811 117.776 130.269 1.00 35.87  ? 519  LEU B CB  1 
ATOM   7910  C CG  . LEU B 1 519 ? 104.375 117.262 131.638 1.00 35.87  ? 519  LEU B CG  1 
ATOM   7911  C CD1 . LEU B 1 519 ? 103.955 118.402 132.535 1.00 35.87  ? 519  LEU B CD1 1 
ATOM   7912  C CD2 . LEU B 1 519 ? 103.250 116.252 131.491 1.00 35.87  ? 519  LEU B CD2 1 
ATOM   7913  N N   . ILE B 1 520 ? 107.351 117.837 128.101 1.00 35.43  ? 520  ILE B N   1 
ATOM   7914  C CA  . ILE B 1 520 ? 107.950 118.275 126.842 1.00 35.43  ? 520  ILE B CA  1 
ATOM   7915  C C   . ILE B 1 520 ? 107.970 117.156 125.815 1.00 35.43  ? 520  ILE B C   1 
ATOM   7916  O O   . ILE B 1 520 ? 107.666 117.395 124.638 1.00 35.43  ? 520  ILE B O   1 
ATOM   7917  C CB  . ILE B 1 520 ? 109.369 118.818 127.103 1.00 35.43  ? 520  ILE B CB  1 
ATOM   7918  C CG1 . ILE B 1 520 ? 109.315 120.047 128.002 1.00 35.43  ? 520  ILE B CG1 1 
ATOM   7919  C CG2 . ILE B 1 520 ? 110.080 119.184 125.814 1.00 35.43  ? 520  ILE B CG2 1 
ATOM   7920  C CD1 . ILE B 1 520 ? 110.664 120.605 128.352 1.00 35.43  ? 520  ILE B CD1 1 
ATOM   7921  N N   . LEU B 1 521 ? 108.270 115.931 126.244 1.00 38.82  ? 521  LEU B N   1 
ATOM   7922  C CA  . LEU B 1 521 ? 108.268 114.762 125.379 1.00 38.82  ? 521  LEU B CA  1 
ATOM   7923  C C   . LEU B 1 521 ? 106.898 114.453 124.798 1.00 38.82  ? 521  LEU B C   1 
ATOM   7924  O O   . LEU B 1 521 ? 106.816 113.992 123.656 1.00 38.82  ? 521  LEU B O   1 
ATOM   7925  C CB  . LEU B 1 521 ? 108.782 113.543 126.152 1.00 38.82  ? 521  LEU B CB  1 
ATOM   7926  C CG  . LEU B 1 521 ? 109.127 112.272 125.376 1.00 38.82  ? 521  LEU B CG  1 
ATOM   7927  C CD1 . LEU B 1 521 ? 110.184 112.548 124.342 1.00 38.82  ? 521  LEU B CD1 1 
ATOM   7928  C CD2 . LEU B 1 521 ? 109.600 111.198 126.330 1.00 38.82  ? 521  LEU B CD2 1 
ATOM   7929  N N   . ILE B 1 522 ? 105.826 114.713 125.540 1.00 40.61  ? 522  ILE B N   1 
ATOM   7930  C CA  . ILE B 1 522 ? 104.475 114.443 125.072 1.00 40.61  ? 522  ILE B CA  1 
ATOM   7931  C C   . ILE B 1 522 ? 103.735 115.733 124.724 1.00 40.61  ? 522  ILE B C   1 
ATOM   7932  O O   . ILE B 1 522 ? 102.524 115.717 124.542 1.00 40.61  ? 522  ILE B O   1 
ATOM   7933  C CB  . ILE B 1 522 ? 103.694 113.610 126.104 1.00 40.61  ? 522  ILE B CB  1 
ATOM   7934  C CG1 . ILE B 1 522 ? 103.537 114.395 127.406 1.00 40.61  ? 522  ILE B CG1 1 
ATOM   7935  C CG2 . ILE B 1 522 ? 104.407 112.299 126.355 1.00 40.61  ? 522  ILE B CG2 1 
ATOM   7936  C CD1 . ILE B 1 522 ? 102.900 113.618 128.538 1.00 40.61  ? 522  ILE B CD1 1 
ATOM   7937  N N   . CYS B 1 523 ? 104.458 116.850 124.637 1.00 43.56  ? 523  CYS B N   1 
ATOM   7938  C CA  . CYS B 1 523 ? 103.874 118.139 124.262 1.00 43.56  ? 523  CYS B CA  1 
ATOM   7939  C C   . CYS B 1 523 ? 103.363 118.098 122.830 1.00 43.56  ? 523  CYS B C   1 
ATOM   7940  O O   . CYS B 1 523 ? 104.149 117.843 121.910 1.00 43.56  ? 523  CYS B O   1 
ATOM   7941  C CB  . CYS B 1 523 ? 104.900 119.254 124.409 1.00 43.56  ? 523  CYS B CB  1 
ATOM   7942  S SG  . CYS B 1 523 ? 104.444 120.779 123.567 1.00 43.56  ? 523  CYS B SG  1 
ATOM   7943  N N   . PRO B 1 524 ? 102.076 118.335 122.591 1.00 42.65  ? 524  PRO B N   1 
ATOM   7944  C CA  . PRO B 1 524 ? 101.508 118.127 121.256 1.00 42.65  ? 524  PRO B CA  1 
ATOM   7945  C C   . PRO B 1 524 ? 101.443 119.360 120.367 1.00 42.65  ? 524  PRO B C   1 
ATOM   7946  O O   . PRO B 1 524 ? 100.757 119.298 119.343 1.00 42.65  ? 524  PRO B O   1 
ATOM   7947  C CB  . PRO B 1 524 ? 100.092 117.649 121.592 1.00 42.65  ? 524  PRO B CB  1 
ATOM   7948  C CG  . PRO B 1 524 ? 99.748  118.402 122.835 1.00 42.65  ? 524  PRO B CG  1 
ATOM   7949  C CD  . PRO B 1 524 ? 101.036 118.693 123.570 1.00 42.65  ? 524  PRO B CD  1 
ATOM   7950  N N   . LEU B 1 525 ? 102.091 120.478 120.708 1.00 39.99  ? 525  LEU B N   1 
ATOM   7951  C CA  . LEU B 1 525 ? 101.714 121.677 119.975 1.00 39.99  ? 525  LEU B CA  1 
ATOM   7952  C C   . LEU B 1 525 ? 102.440 121.830 118.642 1.00 39.99  ? 525  LEU B C   1 
ATOM   7953  O O   . LEU B 1 525 ? 101.912 121.382 117.619 1.00 39.99  ? 525  LEU B O   1 
ATOM   7954  C CB  . LEU B 1 525 ? 101.967 122.895 120.866 1.00 39.99  ? 525  LEU B CB  1 
ATOM   7955  C CG  . LEU B 1 525 ? 101.485 122.703 122.310 1.00 39.99  ? 525  LEU B CG  1 
ATOM   7956  C CD1 . LEU B 1 525 ? 102.036 123.765 123.234 1.00 39.99  ? 525  LEU B CD1 1 
ATOM   7957  C CD2 . LEU B 1 525 ? 99.971  122.700 122.373 1.00 39.99  ? 525  LEU B CD2 1 
ATOM   7958  N N   . ASN B 1 526 ? 103.643 122.416 118.630 1.00 32.19  ? 526  ASN B N   1 
ATOM   7959  C CA  . ASN B 1 526 ? 104.582 122.268 117.519 1.00 32.19  ? 526  ASN B CA  1 
ATOM   7960  C C   . ASN B 1 526 ? 106.015 122.569 117.933 1.00 32.19  ? 526  ASN B C   1 
ATOM   7961  O O   . ASN B 1 526 ? 106.912 122.569 117.084 1.00 32.19  ? 526  ASN B O   1 
ATOM   7962  C CB  . ASN B 1 526 ? 104.216 123.162 116.329 1.00 32.19  ? 526  ASN B CB  1 
ATOM   7963  C CG  . ASN B 1 526 ? 104.615 122.543 114.997 1.00 32.19  ? 526  ASN B CG  1 
ATOM   7964  O OD1 . ASN B 1 526 ? 105.192 121.459 114.954 1.00 32.19  ? 526  ASN B OD1 1 
ATOM   7965  N ND2 . ASN B 1 526 ? 104.307 123.230 113.907 1.00 32.19  ? 526  ASN B ND2 1 
ATOM   7966  N N   . ILE B 1 527 ? 106.241 122.867 119.210 1.00 35.06  ? 527  ILE B N   1 
ATOM   7967  C CA  . ILE B 1 527 ? 107.424 123.638 119.588 1.00 35.06  ? 527  ILE B CA  1 
ATOM   7968  C C   . ILE B 1 527 ? 108.680 122.777 119.550 1.00 35.06  ? 527  ILE B C   1 
ATOM   7969  O O   . ILE B 1 527 ? 109.604 123.026 118.765 1.00 35.06  ? 527  ILE B O   1 
ATOM   7970  C CB  . ILE B 1 527 ? 107.239 124.270 120.978 1.00 35.06  ? 527  ILE B CB  1 
ATOM   7971  C CG1 . ILE B 1 527 ? 105.797 124.713 121.186 1.00 35.06  ? 527  ILE B CG1 1 
ATOM   7972  C CG2 . ILE B 1 527 ? 108.171 125.461 121.137 1.00 35.06  ? 527  ILE B CG2 1 
ATOM   7973  C CD1 . ILE B 1 527 ? 105.483 125.007 122.627 1.00 35.06  ? 527  ILE B CD1 1 
ATOM   7974  N N   . PHE B 1 528 ? 108.731 121.753 120.396 1.00 32.13  ? 528  PHE B N   1 
ATOM   7975  C CA  . PHE B 1 528 ? 109.959 120.993 120.610 1.00 32.13  ? 528  PHE B CA  1 
ATOM   7976  C C   . PHE B 1 528 ? 109.963 119.751 119.724 1.00 32.13  ? 528  PHE B C   1 
ATOM   7977  O O   . PHE B 1 528 ? 109.801 118.622 120.184 1.00 32.13  ? 528  PHE B O   1 
ATOM   7978  C CB  . PHE B 1 528 ? 110.099 120.634 122.080 1.00 32.13  ? 528  PHE B CB  1 
ATOM   7979  C CG  . PHE B 1 528 ? 109.992 121.810 122.992 1.00 32.13  ? 528  PHE B CG  1 
ATOM   7980  C CD1 . PHE B 1 528 ? 110.978 122.781 123.004 1.00 32.13  ? 528  PHE B CD1 1 
ATOM   7981  C CD2 . PHE B 1 528 ? 108.900 121.953 123.827 1.00 32.13  ? 528  PHE B CD2 1 
ATOM   7982  C CE1 . PHE B 1 528 ? 110.884 123.869 123.841 1.00 32.13  ? 528  PHE B CE1 1 
ATOM   7983  C CE2 . PHE B 1 528 ? 108.798 123.036 124.666 1.00 32.13  ? 528  PHE B CE2 1 
ATOM   7984  C CZ  . PHE B 1 528 ? 109.793 123.996 124.675 1.00 32.13  ? 528  PHE B CZ  1 
ATOM   7985  N N   . TYR B 1 529 ? 110.140 120.007 118.424 1.00 25.60  ? 529  TYR B N   1 
ATOM   7986  C CA  . TYR B 1 529 ? 110.355 118.989 117.394 1.00 25.60  ? 529  TYR B CA  1 
ATOM   7987  C C   . TYR B 1 529 ? 109.230 117.960 117.337 1.00 25.60  ? 529  TYR B C   1 
ATOM   7988  O O   . TYR B 1 529 ? 109.469 116.757 117.398 1.00 25.60  ? 529  TYR B O   1 
ATOM   7989  C CB  . TYR B 1 529 ? 111.690 118.275 117.590 1.00 25.60  ? 529  TYR B CB  1 
ATOM   7990  C CG  . TYR B 1 529 ? 112.919 119.100 117.379 1.00 25.60  ? 529  TYR B CG  1 
ATOM   7991  C CD1 . TYR B 1 529 ? 113.604 119.057 116.179 1.00 25.60  ? 529  TYR B CD1 1 
ATOM   7992  C CD2 . TYR B 1 529 ? 113.424 119.884 118.396 1.00 25.60  ? 529  TYR B CD2 1 
ATOM   7993  C CE1 . TYR B 1 529 ? 114.743 119.792 115.992 1.00 25.60  ? 529  TYR B CE1 1 
ATOM   7994  C CE2 . TYR B 1 529 ? 114.561 120.621 118.218 1.00 25.60  ? 529  TYR B CE2 1 
ATOM   7995  C CZ  . TYR B 1 529 ? 115.214 120.570 117.017 1.00 25.60  ? 529  TYR B CZ  1 
ATOM   7996  O OH  . TYR B 1 529 ? 116.348 121.313 116.851 1.00 25.60  ? 529  TYR B OH  1 
ATOM   7997  N N   . LYS B 1 530 ? 107.995 118.427 117.241 1.00 33.56  ? 530  LYS B N   1 
ATOM   7998  C CA  . LYS B 1 530 ? 106.925 117.499 116.913 1.00 33.56  ? 530  LYS B CA  1 
ATOM   7999  C C   . LYS B 1 530 ? 107.111 117.038 115.466 1.00 33.56  ? 530  LYS B C   1 
ATOM   8000  O O   . LYS B 1 530 ? 107.736 117.733 114.659 1.00 33.56  ? 530  LYS B O   1 
ATOM   8001  C CB  . LYS B 1 530 ? 105.566 118.163 117.140 1.00 33.56  ? 530  LYS B CB  1 
ATOM   8002  C CG  . LYS B 1 530 ? 104.357 117.241 117.066 1.00 33.56  ? 530  LYS B CG  1 
ATOM   8003  C CD  . LYS B 1 530 ? 103.071 117.957 117.398 1.00 33.56  ? 530  LYS B CD  1 
ATOM   8004  C CE  . LYS B 1 530 ? 101.877 117.078 117.094 1.00 33.56  ? 530  LYS B CE  1 
ATOM   8005  N NZ  . LYS B 1 530 ? 101.871 115.867 117.952 1.00 33.56  ? 530  LYS B NZ  1 
ATOM   8006  N N   . SER B 1 531 ? 106.578 115.843 115.164 1.00 36.73  ? 531  SER B N   1 
ATOM   8007  C CA  . SER B 1 531 ? 106.798 114.967 114.004 1.00 36.73  ? 531  SER B CA  1 
ATOM   8008  C C   . SER B 1 531 ? 108.149 114.274 114.043 1.00 36.73  ? 531  SER B C   1 
ATOM   8009  O O   . SER B 1 531 ? 108.538 113.641 113.057 1.00 36.73  ? 531  SER B O   1 
ATOM   8010  C CB  . SER B 1 531 ? 106.636 115.654 112.640 1.00 36.73  ? 531  SER B CB  1 
ATOM   8011  O OG  . SER B 1 531 ? 107.869 116.206 112.217 1.00 36.73  ? 531  SER B OG  1 
ATOM   8012  N N   . SER B 1 532 ? 108.881 114.382 115.149 1.00 25.28  ? 532  SER B N   1 
ATOM   8013  C CA  . SER B 1 532 ? 109.933 113.425 115.453 1.00 25.28  ? 532  SER B CA  1 
ATOM   8014  C C   . SER B 1 532 ? 109.944 113.094 116.934 1.00 25.28  ? 532  SER B C   1 
ATOM   8015  O O   . SER B 1 532 ? 110.789 112.312 117.376 1.00 25.28  ? 532  SER B O   1 
ATOM   8016  C CB  . SER B 1 532 ? 111.300 113.941 115.032 1.00 25.28  ? 532  SER B CB  1 
ATOM   8017  O OG  . SER B 1 532 ? 111.944 114.624 116.090 1.00 25.28  ? 532  SER B OG  1 
ATOM   8018  N N   . ARG B 1 533 ? 109.034 113.665 117.699 1.00 31.66  ? 533  ARG B N   1 
ATOM   8019  C CA  . ARG B 1 533 ? 108.870 113.368 119.103 1.00 31.66  ? 533  ARG B CA  1 
ATOM   8020  C C   . ARG B 1 533 ? 107.561 112.659 119.371 1.00 31.66  ? 533  ARG B C   1 
ATOM   8021  O O   . ARG B 1 533 ? 107.372 112.131 120.468 1.00 31.66  ? 533  ARG B O   1 
ATOM   8022  C CB  . ARG B 1 533 ? 108.940 114.670 119.908 1.00 31.66  ? 533  ARG B CB  1 
ATOM   8023  C CG  . ARG B 1 533 ? 109.173 114.581 121.389 1.00 31.66  ? 533  ARG B CG  1 
ATOM   8024  C CD  . ARG B 1 533 ? 109.113 115.972 122.003 1.00 31.66  ? 533  ARG B CD  1 
ATOM   8025  N NE  . ARG B 1 533 ? 108.413 116.927 121.147 1.00 31.66  ? 533  ARG B NE  1 
ATOM   8026  C CZ  . ARG B 1 533 ? 107.153 117.304 121.312 1.00 31.66  ? 533  ARG B CZ  1 
ATOM   8027  N NH1 . ARG B 1 533 ? 106.442 116.812 122.312 1.00 31.66  ? 533  ARG B NH1 1 
ATOM   8028  N NH2 . ARG B 1 533 ? 106.605 118.167 120.472 1.00 31.66  ? 533  ARG B NH2 1 
ATOM   8029  N N   . TYR B 1 534 ? 106.656 112.627 118.398 1.00 37.31  ? 534  TYR B N   1 
ATOM   8030  C CA  . TYR B 1 534 ? 105.525 111.718 118.442 1.00 37.31  ? 534  TYR B CA  1 
ATOM   8031  C C   . TYR B 1 534 ? 105.756 110.480 117.593 1.00 37.31  ? 534  TYR B C   1 
ATOM   8032  O O   . TYR B 1 534 ? 105.020 109.499 117.740 1.00 37.31  ? 534  TYR B O   1 
ATOM   8033  C CB  . TYR B 1 534 ? 104.244 112.434 118.006 1.00 37.31  ? 534  TYR B CB  1 
ATOM   8034  C CG  . TYR B 1 534 ? 103.519 113.062 119.172 1.00 37.31  ? 534  TYR B CG  1 
ATOM   8035  C CD1 . TYR B 1 534 ? 102.303 112.558 119.617 1.00 37.31  ? 534  TYR B CD1 1 
ATOM   8036  C CD2 . TYR B 1 534 ? 104.070 114.140 119.850 1.00 37.31  ? 534  TYR B CD2 1 
ATOM   8037  C CE1 . TYR B 1 534 ? 101.653 113.124 120.695 1.00 37.31  ? 534  TYR B CE1 1 
ATOM   8038  C CE2 . TYR B 1 534 ? 103.428 114.711 120.925 1.00 37.31  ? 534  TYR B CE2 1 
ATOM   8039  C CZ  . TYR B 1 534 ? 102.224 114.201 121.344 1.00 37.31  ? 534  TYR B CZ  1 
ATOM   8040  O OH  . TYR B 1 534 ? 101.593 114.780 122.419 1.00 37.31  ? 534  TYR B OH  1 
ATOM   8041  N N   . ARG B 1 535 ? 106.758 110.502 116.712 1.00 28.61  ? 535  ARG B N   1 
ATOM   8042  C CA  . ARG B 1 535 ? 107.227 109.262 116.104 1.00 28.61  ? 535  ARG B CA  1 
ATOM   8043  C C   . ARG B 1 535 ? 107.981 108.419 117.121 1.00 28.61  ? 535  ARG B C   1 
ATOM   8044  O O   . ARG B 1 535 ? 107.938 107.187 117.075 1.00 28.61  ? 535  ARG B O   1 
ATOM   8045  C CB  . ARG B 1 535 ? 108.113 109.560 114.899 1.00 28.61  ? 535  ARG B CB  1 
ATOM   8046  C CG  . ARG B 1 535 ? 108.484 108.340 114.091 1.00 28.61  ? 535  ARG B CG  1 
ATOM   8047  C CD  . ARG B 1 535 ? 109.286 108.720 112.870 1.00 28.61  ? 535  ARG B CD  1 
ATOM   8048  N NE  . ARG B 1 535 ? 109.696 107.543 112.113 1.00 28.61  ? 535  ARG B NE  1 
ATOM   8049  C CZ  . ARG B 1 535 ? 108.963 106.978 111.162 1.00 28.61  ? 535  ARG B CZ  1 
ATOM   8050  N NH1 . ARG B 1 535 ? 107.784 107.487 110.846 1.00 28.61  ? 535  ARG B NH1 1 
ATOM   8051  N NH2 . ARG B 1 535 ? 109.408 105.907 110.526 1.00 28.61  ? 535  ARG B NH2 1 
ATOM   8052  N N   . LEU B 1 536 ? 108.676 109.065 118.052 1.00 21.64  ? 536  LEU B N   1 
ATOM   8053  C CA  . LEU B 1 536 ? 109.377 108.327 119.092 1.00 21.64  ? 536  LEU B CA  1 
ATOM   8054  C C   . LEU B 1 536 ? 108.418 107.718 120.104 1.00 21.64  ? 536  LEU B C   1 
ATOM   8055  O O   . LEU B 1 536 ? 108.792 106.762 120.783 1.00 21.64  ? 536  LEU B O   1 
ATOM   8056  C CB  . LEU B 1 536 ? 110.393 109.244 119.773 1.00 21.64  ? 536  LEU B CB  1 
ATOM   8057  C CG  . LEU B 1 536 ? 111.481 108.726 120.703 1.00 21.64  ? 536  LEU B CG  1 
ATOM   8058  C CD1 . LEU B 1 536 ? 112.683 109.613 120.527 1.00 21.64  ? 536  LEU B CD1 1 
ATOM   8059  C CD2 . LEU B 1 536 ? 111.045 108.781 122.134 1.00 21.64  ? 536  LEU B CD2 1 
ATOM   8060  N N   . ILE B 1 537 ? 107.192 108.235 120.225 1.00 23.54  ? 537  ILE B N   1 
ATOM   8061  C CA  . ILE B 1 537 ? 106.184 107.542 121.023 1.00 23.54  ? 537  ILE B CA  1 
ATOM   8062  C C   . ILE B 1 537 ? 105.364 106.604 120.146 1.00 23.54  ? 537  ILE B C   1 
ATOM   8063  O O   . ILE B 1 537 ? 104.508 105.868 120.656 1.00 23.54  ? 537  ILE B O   1 
ATOM   8064  C CB  . ILE B 1 537 ? 105.290 108.536 121.796 1.00 23.54  ? 537  ILE B CB  1 
ATOM   8065  C CG1 . ILE B 1 537 ? 106.092 109.755 122.241 1.00 23.54  ? 537  ILE B CG1 1 
ATOM   8066  C CG2 . ILE B 1 537 ? 104.724 107.909 123.076 1.00 23.54  ? 537  ILE B CG2 1 
ATOM   8067  C CD1 . ILE B 1 537 ? 107.131 109.494 123.326 1.00 23.54  ? 537  ILE B CD1 1 
ATOM   8068  N N   . SER B 1 538 ? 105.611 106.586 118.842 1.00 27.00  ? 538  SER B N   1 
ATOM   8069  C CA  . SER B 1 538 ? 105.154 105.491 118.000 1.00 27.00  ? 538  SER B CA  1 
ATOM   8070  C C   . SER B 1 538 ? 106.108 104.310 118.037 1.00 27.00  ? 538  SER B C   1 
ATOM   8071  O O   . SER B 1 538 ? 105.830 103.282 117.417 1.00 27.00  ? 538  SER B O   1 
ATOM   8072  C CB  . SER B 1 538 ? 104.967 105.963 116.557 1.00 27.00  ? 538  SER B CB  1 
ATOM   8073  O OG  . SER B 1 538 ? 104.659 104.879 115.702 1.00 27.00  ? 538  SER B OG  1 
ATOM   8074  N N   . VAL B 1 539 ? 107.222 104.435 118.758 1.00 24.85  ? 539  VAL B N   1 
ATOM   8075  C CA  . VAL B 1 539 ? 108.229 103.391 118.868 1.00 24.85  ? 539  VAL B CA  1 
ATOM   8076  C C   . VAL B 1 539 ? 108.192 102.730 120.238 1.00 24.85  ? 539  VAL B C   1 
ATOM   8077  O O   . VAL B 1 539 ? 108.130 101.506 120.342 1.00 24.85  ? 539  VAL B O   1 
ATOM   8078  C CB  . VAL B 1 539 ? 109.638 103.938 118.562 1.00 24.85  ? 539  VAL B CB  1 
ATOM   8079  C CG1 . VAL B 1 539 ? 110.654 102.886 118.782 1.00 24.85  ? 539  VAL B CG1 1 
ATOM   8080  C CG2 . VAL B 1 539 ? 109.711 104.403 117.137 1.00 24.85  ? 539  VAL B CG2 1 
ATOM   8081  N N   . ILE B 1 540 ? 108.128 103.529 121.303 1.00 23.60  ? 540  ILE B N   1 
ATOM   8082  C CA  . ILE B 1 540 ? 108.096 102.991 122.660 1.00 23.60  ? 540  ILE B CA  1 
ATOM   8083  C C   . ILE B 1 540 ? 106.650 102.705 123.057 1.00 23.60  ? 540  ILE B C   1 
ATOM   8084  O O   . ILE B 1 540 ? 106.340 102.468 124.227 1.00 23.60  ? 540  ILE B O   1 
ATOM   8085  C CB  . ILE B 1 540 ? 108.792 103.936 123.655 1.00 23.60  ? 540  ILE B CB  1 
ATOM   8086  C CG1 . ILE B 1 540 ? 109.970 104.611 122.976 1.00 23.60  ? 540  ILE B CG1 1 
ATOM   8087  C CG2 . ILE B 1 540 ? 109.372 103.166 124.824 1.00 23.60  ? 540  ILE B CG2 1 
ATOM   8088  C CD1 . ILE B 1 540 ? 110.774 105.504 123.878 1.00 23.60  ? 540  ILE B CD1 1 
ATOM   8089  N N   . ARG B 1 541 ? 105.744 102.738 122.089 1.00 39.23  ? 541  ARG B N   1 
ATOM   8090  C CA  . ARG B 1 541 ? 104.443 102.117 122.268 1.00 39.23  ? 541  ARG B CA  1 
ATOM   8091  C C   . ARG B 1 541 ? 104.441 100.678 121.781 1.00 39.23  ? 541  ARG B C   1 
ATOM   8092  O O   . ARG B 1 541 ? 103.812 99.821  122.410 1.00 39.23  ? 541  ARG B O   1 
ATOM   8093  C CB  . ARG B 1 541 ? 103.373 102.926 121.537 1.00 39.23  ? 541  ARG B CB  1 
ATOM   8094  C CG  . ARG B 1 541 ? 101.964 102.406 121.677 1.00 39.23  ? 541  ARG B CG  1 
ATOM   8095  C CD  . ARG B 1 541 ? 101.010 103.344 120.974 1.00 39.23  ? 541  ARG B CD  1 
ATOM   8096  N NE  . ARG B 1 541 ? 101.347 103.488 119.563 1.00 39.23  ? 541  ARG B NE  1 
ATOM   8097  C CZ  . ARG B 1 541 ? 100.943 102.658 118.611 1.00 39.23  ? 541  ARG B CZ  1 
ATOM   8098  N NH1 . ARG B 1 541 ? 100.170 101.626 118.912 1.00 39.23  ? 541  ARG B NH1 1 
ATOM   8099  N NH2 . ARG B 1 541 ? 101.305 102.869 117.355 1.00 39.23  ? 541  ARG B NH2 1 
ATOM   8100  N N   . ASN B 1 542 ? 105.157 100.384 120.696 1.00 36.44  ? 542  ASN B N   1 
ATOM   8101  C CA  . ASN B 1 542 ? 105.240 99.007  120.228 1.00 36.44  ? 542  ASN B CA  1 
ATOM   8102  C C   . ASN B 1 542 ? 106.101 98.148  121.138 1.00 36.44  ? 542  ASN B C   1 
ATOM   8103  O O   . ASN B 1 542 ? 105.855 96.947  121.262 1.00 36.44  ? 542  ASN B O   1 
ATOM   8104  C CB  . ASN B 1 542 ? 105.805 98.940  118.811 1.00 36.44  ? 542  ASN B CB  1 
ATOM   8105  C CG  . ASN B 1 542 ? 105.104 99.861  117.846 1.00 36.44  ? 542  ASN B CG  1 
ATOM   8106  O OD1 . ASN B 1 542 ? 105.727 100.411 116.942 1.00 36.44  ? 542  ASN B OD1 1 
ATOM   8107  N ND2 . ASN B 1 542 ? 103.801 100.023 118.017 1.00 36.44  ? 542  ASN B ND2 1 
ATOM   8108  N N   . ILE B 1 543 ? 107.114 98.731  121.771 1.00 30.12  ? 543  ILE B N   1 
ATOM   8109  C CA  . ILE B 1 543 ? 108.111 97.928  122.470 1.00 30.12  ? 543  ILE B CA  1 
ATOM   8110  C C   . ILE B 1 543 ? 107.571 97.453  123.814 1.00 30.12  ? 543  ILE B C   1 
ATOM   8111  O O   . ILE B 1 543 ? 107.818 96.315  124.231 1.00 30.12  ? 543  ILE B O   1 
ATOM   8112  C CB  . ILE B 1 543 ? 109.418 98.729  122.611 1.00 30.12  ? 543  ILE B CB  1 
ATOM   8113  C CG1 . ILE B 1 543 ? 110.019 98.979  121.238 1.00 30.12  ? 543  ILE B CG1 1 
ATOM   8114  C CG2 . ILE B 1 543 ? 110.439 98.003  123.426 1.00 30.12  ? 543  ILE B CG2 1 
ATOM   8115  C CD1 . ILE B 1 543 ? 110.968 100.107 121.228 1.00 30.12  ? 543  ILE B CD1 1 
ATOM   8116  N N   . VAL B 1 544 ? 106.785 98.292  124.491 1.00 35.10  ? 544  VAL B N   1 
ATOM   8117  C CA  . VAL B 1 544 ? 106.286 97.927  125.816 1.00 35.10  ? 544  VAL B CA  1 
ATOM   8118  C C   . VAL B 1 544 ? 105.166 96.899  125.702 1.00 35.10  ? 544  VAL B C   1 
ATOM   8119  O O   . VAL B 1 544 ? 105.049 95.988  126.530 1.00 35.10  ? 544  VAL B O   1 
ATOM   8120  C CB  . VAL B 1 544 ? 105.841 99.179  126.586 1.00 35.10  ? 544  VAL B CB  1 
ATOM   8121  C CG1 . VAL B 1 544 ? 105.587 98.840  128.032 1.00 35.10  ? 544  VAL B CG1 1 
ATOM   8122  C CG2 . VAL B 1 544 ? 106.916 100.219 126.512 1.00 35.10  ? 544  VAL B CG2 1 
ATOM   8123  N N   . PHE B 1 545 ? 104.339 97.011  124.669 1.00 41.13  ? 545  PHE B N   1 
ATOM   8124  C CA  . PHE B 1 545 ? 103.411 95.929  124.337 1.00 41.13  ? 545  PHE B CA  1 
ATOM   8125  C C   . PHE B 1 545 ? 104.203 94.907  123.538 1.00 41.13  ? 545  PHE B C   1 
ATOM   8126  O O   . PHE B 1 545 ? 104.148 94.869  122.309 1.00 41.13  ? 545  PHE B O   1 
ATOM   8127  C CB  . PHE B 1 545 ? 102.209 96.443  123.558 1.00 41.13  ? 545  PHE B CB  1 
ATOM   8128  C CG  . PHE B 1 545 ? 101.293 97.305  124.361 1.00 41.13  ? 545  PHE B CG  1 
ATOM   8129  C CD1 . PHE B 1 545 ? 101.264 97.211  125.743 1.00 41.13  ? 545  PHE B CD1 1 
ATOM   8130  C CD2 . PHE B 1 545 ? 100.450 98.201  123.736 1.00 41.13  ? 545  PHE B CD2 1 
ATOM   8131  C CE1 . PHE B 1 545 ? 100.425 98.003  126.485 1.00 41.13  ? 545  PHE B CE1 1 
ATOM   8132  C CE2 . PHE B 1 545 ? 99.603  98.994  124.469 1.00 41.13  ? 545  PHE B CE2 1 
ATOM   8133  C CZ  . PHE B 1 545 ? 99.590  98.896  125.848 1.00 41.13  ? 545  PHE B CZ  1 
ATOM   8134  N N   . SER B 1 546 ? 104.926 94.042  124.262 1.00 35.96  ? 546  SER B N   1 
ATOM   8135  C CA  . SER B 1 546 ? 106.043 93.321  123.655 1.00 35.96  ? 546  SER B CA  1 
ATOM   8136  C C   . SER B 1 546 ? 105.653 92.245  122.641 1.00 35.96  ? 546  SER B C   1 
ATOM   8137  O O   . SER B 1 546 ? 106.118 92.326  121.490 1.00 35.96  ? 546  SER B O   1 
ATOM   8138  C CB  . SER B 1 546 ? 106.981 92.806  124.751 1.00 35.96  ? 546  SER B CB  1 
ATOM   8139  O OG  . SER B 1 546 ? 106.318 92.054  125.745 1.00 35.96  ? 546  SER B OG  1 
ATOM   8140  N N   . PRO B 1 547 ? 104.839 91.218  122.963 1.00 41.25  ? 547  PRO B N   1 
ATOM   8141  C CA  . PRO B 1 547 ? 104.707 90.114  122.000 1.00 41.25  ? 547  PRO B CA  1 
ATOM   8142  C C   . PRO B 1 547 ? 103.839 90.436  120.797 1.00 41.25  ? 547  PRO B C   1 
ATOM   8143  O O   . PRO B 1 547 ? 103.915 89.715  119.796 1.00 41.25  ? 547  PRO B O   1 
ATOM   8144  C CB  . PRO B 1 547 ? 104.089 88.996  122.839 1.00 41.25  ? 547  PRO B CB  1 
ATOM   8145  C CG  . PRO B 1 547 ? 103.212 89.699  123.754 1.00 41.25  ? 547  PRO B CG  1 
ATOM   8146  C CD  . PRO B 1 547 ? 103.852 91.031  124.054 1.00 41.25  ? 547  PRO B CD  1 
ATOM   8147  N N   . LEU B 1 548 ? 103.042 91.495  120.856 1.00 46.30  ? 548  LEU B N   1 
ATOM   8148  C CA  . LEU B 1 548 ? 102.313 92.009  119.709 1.00 46.30  ? 548  LEU B CA  1 
ATOM   8149  C C   . LEU B 1 548 ? 103.234 92.965  118.950 1.00 46.30  ? 548  LEU B C   1 
ATOM   8150  O O   . LEU B 1 548 ? 104.440 93.000  119.212 1.00 46.30  ? 548  LEU B O   1 
ATOM   8151  C CB  . LEU B 1 548 ? 101.027 92.706  120.165 1.00 46.30  ? 548  LEU B CB  1 
ATOM   8152  C CG  . LEU B 1 548 ? 100.093 91.994  121.141 1.00 46.30  ? 548  LEU B CG  1 
ATOM   8153  C CD1 . LEU B 1 548 ? 100.284 92.537  122.546 1.00 46.30  ? 548  LEU B CD1 1 
ATOM   8154  C CD2 . LEU B 1 548 ? 98.653  92.153  120.703 1.00 46.30  ? 548  LEU B CD2 1 
ATOM   8155  N N   . TYR B 1 549 ? 102.665 93.745  118.021 1.00 43.15  ? 549  TYR B N   1 
ATOM   8156  C CA  . TYR B 1 549 ? 103.297 94.924  117.422 1.00 43.15  ? 549  TYR B CA  1 
ATOM   8157  C C   . TYR B 1 549 ? 104.591 94.562  116.686 1.00 43.15  ? 549  TYR B C   1 
ATOM   8158  O O   . TYR B 1 549 ? 105.699 94.795  117.177 1.00 43.15  ? 549  TYR B O   1 
ATOM   8159  C CB  . TYR B 1 549 ? 103.537 96.000  118.484 1.00 43.15  ? 549  TYR B CB  1 
ATOM   8160  C CG  . TYR B 1 549 ? 102.329 96.855  118.748 1.00 43.15  ? 549  TYR B CG  1 
ATOM   8161  C CD1 . TYR B 1 549 ? 101.540 97.315  117.704 1.00 43.15  ? 549  TYR B CD1 1 
ATOM   8162  C CD2 . TYR B 1 549 ? 101.981 97.206  120.041 1.00 43.15  ? 549  TYR B CD2 1 
ATOM   8163  C CE1 . TYR B 1 549 ? 100.439 98.099  117.944 1.00 43.15  ? 549  TYR B CE1 1 
ATOM   8164  C CE2 . TYR B 1 549 ? 100.884 97.991  120.289 1.00 43.15  ? 549  TYR B CE2 1 
ATOM   8165  C CZ  . TYR B 1 549 ? 100.115 98.432  119.241 1.00 43.15  ? 549  TYR B CZ  1 
ATOM   8166  O OH  . TYR B 1 549 ? 99.017  99.216  119.495 1.00 43.15  ? 549  TYR B OH  1 
ATOM   8167  N N   . LYS B 1 550 ? 104.396 93.905  115.534 1.00 36.51  ? 550  LYS B N   1 
ATOM   8168  C CA  . LYS B 1 550 ? 105.433 93.358  114.656 1.00 36.51  ? 550  LYS B CA  1 
ATOM   8169  C C   . LYS B 1 550 ? 106.618 94.285  114.402 1.00 36.51  ? 550  LYS B C   1 
ATOM   8170  O O   . LYS B 1 550 ? 106.462 95.508  114.351 1.00 36.51  ? 550  LYS B O   1 
ATOM   8171  C CB  . LYS B 1 550 ? 104.805 92.986  113.317 1.00 36.51  ? 550  LYS B CB  1 
ATOM   8172  C CG  . LYS B 1 550 ? 103.945 94.086  112.724 1.00 36.51  ? 550  LYS B CG  1 
ATOM   8173  C CD  . LYS B 1 550 ? 103.794 93.909  111.226 1.00 36.51  ? 550  LYS B CD  1 
ATOM   8174  C CE  . LYS B 1 550 ? 103.146 92.574  110.899 1.00 36.51  ? 550  LYS B CE  1 
ATOM   8175  N NZ  . LYS B 1 550 ? 102.888 92.420  109.445 1.00 36.51  ? 550  LYS B NZ  1 
ATOM   8176  N N   . VAL B 1 551 ? 107.802 93.711  114.239 1.00 27.64  ? 551  VAL B N   1 
ATOM   8177  C CA  . VAL B 1 551 ? 109.043 94.471  114.313 1.00 27.64  ? 551  VAL B CA  1 
ATOM   8178  C C   . VAL B 1 551 ? 109.385 95.037  112.943 1.00 27.64  ? 551  VAL B C   1 
ATOM   8179  O O   . VAL B 1 551 ? 109.424 94.304  111.949 1.00 27.64  ? 551  VAL B O   1 
ATOM   8180  C CB  . VAL B 1 551 ? 110.188 93.599  114.840 1.00 27.64  ? 551  VAL B CB  1 
ATOM   8181  C CG1 . VAL B 1 551 ? 111.335 94.467  115.288 1.00 27.64  ? 551  VAL B CG1 1 
ATOM   8182  C CG2 . VAL B 1 551 ? 109.701 92.718  115.968 1.00 27.64  ? 551  VAL B CG2 1 
ATOM   8183  N N   . VAL B 1 552 ? 109.627 96.341  112.893 1.00 21.93  ? 552  VAL B N   1 
ATOM   8184  C CA  . VAL B 1 552 ? 110.315 96.967  111.783 1.00 21.93  ? 552  VAL B CA  1 
ATOM   8185  C C   . VAL B 1 552 ? 111.649 97.479  112.301 1.00 21.93  ? 552  VAL B C   1 
ATOM   8186  O O   . VAL B 1 552 ? 111.997 97.294  113.464 1.00 21.93  ? 552  VAL B O   1 
ATOM   8187  C CB  . VAL B 1 552 ? 109.475 98.086  111.138 1.00 21.93  ? 552  VAL B CB  1 
ATOM   8188  C CG1 . VAL B 1 552 ? 108.200 97.512  110.564 1.00 21.93  ? 552  VAL B CG1 1 
ATOM   8189  C CG2 . VAL B 1 552 ? 109.154 99.145  112.152 1.00 21.93  ? 552  VAL B CG2 1 
ATOM   8190  N N   . MET B 1 553 ? 112.430 98.115  111.426 1.00 19.06  ? 553  MET B N   1 
ATOM   8191  C CA  . MET B 1 553 ? 113.810 98.429  111.779 1.00 19.06  ? 553  MET B CA  1 
ATOM   8192  C C   . MET B 1 553 ? 113.900 99.550  112.804 1.00 19.06  ? 553  MET B C   1 
ATOM   8193  O O   . MET B 1 553 ? 114.839 99.582  113.604 1.00 19.06  ? 553  MET B O   1 
ATOM   8194  C CB  . MET B 1 553 ? 114.597 98.780  110.526 1.00 19.06  ? 553  MET B CB  1 
ATOM   8195  C CG  . MET B 1 553 ? 116.075 98.989  110.744 1.00 19.06  ? 553  MET B CG  1 
ATOM   8196  S SD  . MET B 1 553 ? 116.823 97.614  111.606 1.00 19.06  ? 553  MET B SD  1 
ATOM   8197  C CE  . MET B 1 553 ? 118.510 98.172  111.652 1.00 19.06  ? 553  MET B CE  1 
ATOM   8198  N N   . LEU B 1 554 ? 112.921 100.442 112.847 1.00 25.58  ? 554  LEU B N   1 
ATOM   8199  C CA  . LEU B 1 554 ? 112.885 101.462 113.892 1.00 25.58  ? 554  LEU B CA  1 
ATOM   8200  C C   . LEU B 1 554 ? 111.839 101.072 114.935 1.00 25.58  ? 554  LEU B C   1 
ATOM   8201  O O   . LEU B 1 554 ? 111.106 101.887 115.485 1.00 25.58  ? 554  LEU B O   1 
ATOM   8202  C CB  . LEU B 1 554 ? 112.620 102.838 113.293 1.00 25.58  ? 554  LEU B CB  1 
ATOM   8203  C CG  . LEU B 1 554 ? 113.218 103.980 114.116 1.00 25.58  ? 554  LEU B CG  1 
ATOM   8204  C CD1 . LEU B 1 554 ? 114.724 103.881 114.160 1.00 25.58  ? 554  LEU B CD1 1 
ATOM   8205  C CD2 . LEU B 1 554 ? 112.787 105.308 113.565 1.00 25.58  ? 554  LEU B CD2 1 
ATOM   8206  N N   . ASP B 1 555 ? 111.765 99.769  115.165 1.00 24.80  ? 555  ASP B N   1 
ATOM   8207  C CA  . ASP B 1 555 ? 111.006 99.206  116.268 1.00 24.80  ? 555  ASP B CA  1 
ATOM   8208  C C   . ASP B 1 555 ? 111.937 98.238  116.969 1.00 24.80  ? 555  ASP B C   1 
ATOM   8209  O O   . ASP B 1 555 ? 111.819 97.991  118.168 1.00 24.80  ? 555  ASP B O   1 
ATOM   8210  C CB  . ASP B 1 555 ? 109.742 98.512  115.761 1.00 24.80  ? 555  ASP B CB  1 
ATOM   8211  C CG  . ASP B 1 555 ? 108.761 98.203  116.863 1.00 24.80  ? 555  ASP B CG  1 
ATOM   8212  O OD1 . ASP B 1 555 ? 108.994 98.646  118.002 1.00 24.80  ? 555  ASP B OD1 1 
ATOM   8213  O OD2 . ASP B 1 555 ? 107.755 97.516  116.589 1.00 24.80  ? 555  ASP B OD2 1 
ATOM   8214  N N   . PHE B 1 556 ? 112.874 97.691  116.207 1.00 18.66  ? 556  PHE B N   1 
ATOM   8215  C CA  . PHE B 1 556 ? 114.018 96.990  116.755 1.00 18.66  ? 556  PHE B CA  1 
ATOM   8216  C C   . PHE B 1 556 ? 115.025 97.904  117.395 1.00 18.66  ? 556  PHE B C   1 
ATOM   8217  O O   . PHE B 1 556 ? 115.513 97.574  118.478 1.00 18.66  ? 556  PHE B O   1 
ATOM   8218  C CB  . PHE B 1 556 ? 114.734 96.182  115.662 1.00 18.66  ? 556  PHE B CB  1 
ATOM   8219  C CG  . PHE B 1 556 ? 116.131 95.773  116.024 1.00 18.66  ? 556  PHE B CG  1 
ATOM   8220  C CD1 . PHE B 1 556 ? 116.364 94.807  116.962 1.00 18.66  ? 556  PHE B CD1 1 
ATOM   8221  C CD2 . PHE B 1 556 ? 117.217 96.355  115.403 1.00 18.66  ? 556  PHE B CD2 1 
ATOM   8222  C CE1 . PHE B 1 556 ? 117.654 94.436  117.293 1.00 18.66  ? 556  PHE B CE1 1 
ATOM   8223  C CE2 . PHE B 1 556 ? 118.503 95.993  115.730 1.00 18.66  ? 556  PHE B CE2 1 
ATOM   8224  C CZ  . PHE B 1 556 ? 118.716 95.034  116.673 1.00 18.66  ? 556  PHE B CZ  1 
ATOM   8225  N N   . PHE B 1 557 ? 115.345 99.034  116.777 1.00 22.51  ? 557  PHE B N   1 
ATOM   8226  C CA  . PHE B 1 557 ? 116.498 99.828  117.155 1.00 22.51  ? 557  PHE B CA  1 
ATOM   8227  C C   . PHE B 1 557 ? 116.354 100.486 118.512 1.00 22.51  ? 557  PHE B C   1 
ATOM   8228  O O   . PHE B 1 557 ? 117.244 100.327 119.344 1.00 22.51  ? 557  PHE B O   1 
ATOM   8229  C CB  . PHE B 1 557 ? 116.759 100.895 116.100 1.00 22.51  ? 557  PHE B CB  1 
ATOM   8230  C CG  . PHE B 1 557 ? 118.150 101.427 116.113 1.00 22.51  ? 557  PHE B CG  1 
ATOM   8231  C CD1 . PHE B 1 557 ? 118.415 102.694 116.586 1.00 22.51  ? 557  PHE B CD1 1 
ATOM   8232  C CD2 . PHE B 1 557 ? 119.190 100.664 115.640 1.00 22.51  ? 557  PHE B CD2 1 
ATOM   8233  C CE1 . PHE B 1 557 ? 119.686 103.183 116.586 1.00 22.51  ? 557  PHE B CE1 1 
ATOM   8234  C CE2 . PHE B 1 557 ? 120.463 101.153 115.640 1.00 22.51  ? 557  PHE B CE2 1 
ATOM   8235  C CZ  . PHE B 1 557 ? 120.708 102.412 116.113 1.00 22.51  ? 557  PHE B CZ  1 
ATOM   8236  N N   . MET B 1 558 ? 115.236 101.148 118.794 1.00 19.62  ? 558  MET B N   1 
ATOM   8237  C CA  . MET B 1 558 ? 115.035 101.811 120.075 1.00 19.62  ? 558  MET B CA  1 
ATOM   8238  C C   . MET B 1 558 ? 114.481 100.847 121.120 1.00 19.62  ? 558  MET B C   1 
ATOM   8239  O O   . MET B 1 558 ? 114.020 101.262 122.184 1.00 19.62  ? 558  MET B O   1 
ATOM   8240  C CB  . MET B 1 558 ? 114.125 103.025 119.902 1.00 19.62  ? 558  MET B CB  1 
ATOM   8241  C CG  . MET B 1 558 ? 114.327 104.189 120.879 1.00 19.62  ? 558  MET B CG  1 
ATOM   8242  S SD  . MET B 1 558 ? 115.984 104.887 120.988 1.00 19.62  ? 558  MET B SD  1 
ATOM   8243  C CE  . MET B 1 558 ? 116.045 105.951 119.546 1.00 19.62  ? 558  MET B CE  1 
ATOM   8244  N N   . ALA B 1 559 ? 114.503 99.554  120.820 1.00 28.09  ? 559  ALA B N   1 
ATOM   8245  C CA  . ALA B 1 559 ? 114.308 98.522  121.817 1.00 28.09  ? 559  ALA B CA  1 
ATOM   8246  C C   . ALA B 1 559 ? 115.617 97.945  122.271 1.00 28.09  ? 559  ALA B C   1 
ATOM   8247  O O   . ALA B 1 559 ? 115.682 97.388  123.368 1.00 28.09  ? 559  ALA B O   1 
ATOM   8248  C CB  . ALA B 1 559 ? 113.442 97.377  121.275 1.00 28.09  ? 559  ALA B CB  1 
ATOM   8249  N N   . ASP B 1 560 ? 116.651 98.054  121.456 1.00 35.55  ? 560  ASP B N   1 
ATOM   8250  C CA  . ASP B 1 560 ? 117.970 97.603  121.809 1.00 35.55  ? 560  ASP B CA  1 
ATOM   8251  C C   . ASP B 1 560 ? 118.907 98.780  121.948 1.00 35.55  ? 560  ASP B C   1 
ATOM   8252  O O   . ASP B 1 560 ? 120.102 98.626  121.738 1.00 35.55  ? 560  ASP B O   1 
ATOM   8253  C CB  . ASP B 1 560 ? 118.477 96.615  120.760 1.00 35.55  ? 560  ASP B CB  1 
ATOM   8254  C CG  . ASP B 1 560 ? 119.508 95.674  121.298 1.00 35.55  ? 560  ASP B CG  1 
ATOM   8255  O OD1 . ASP B 1 560 ? 119.884 95.832  122.467 1.00 35.55  ? 560  ASP B OD1 1 
ATOM   8256  O OD2 . ASP B 1 560 ? 119.930 94.759  120.564 1.00 35.55  ? 560  ASP B OD2 1 
ATOM   8257  N N   . GLN B 1 561 ? 118.378 99.971  122.194 1.00 35.84  ? 561  GLN B N   1 
ATOM   8258  C CA  . GLN B 1 561 ? 119.107 101.072 122.805 1.00 35.84  ? 561  GLN B CA  1 
ATOM   8259  C C   . GLN B 1 561 ? 118.839 101.156 124.291 1.00 35.84  ? 561  GLN B C   1 
ATOM   8260  O O   . GLN B 1 561 ? 119.443 101.977 124.976 1.00 35.84  ? 561  GLN B O   1 
ATOM   8261  C CB  . GLN B 1 561 ? 118.717 102.406 122.178 1.00 35.84  ? 561  GLN B CB  1 
ATOM   8262  C CG  . GLN B 1 561 ? 119.013 102.565 120.742 1.00 35.84  ? 561  GLN B CG  1 
ATOM   8263  C CD  . GLN B 1 561 ? 120.446 102.801 120.484 1.00 35.84  ? 561  GLN B CD  1 
ATOM   8264  O OE1 . GLN B 1 561 ? 120.971 103.876 120.736 1.00 35.84  ? 561  GLN B OE1 1 
ATOM   8265  N NE2 . GLN B 1 561 ? 121.104 101.801 119.967 1.00 35.84  ? 561  GLN B NE2 1 
ATOM   8266  N N   . LEU B 1 562 ? 117.914 100.349 124.786 1.00 35.55  ? 562  LEU B N   1 
ATOM   8267  C CA  . LEU B 1 562 ? 117.552 100.303 126.184 1.00 35.55  ? 562  LEU B CA  1 
ATOM   8268  C C   . LEU B 1 562 ? 118.270 99.206  126.934 1.00 35.55  ? 562  LEU B C   1 
ATOM   8269  O O   . LEU B 1 562 ? 118.120 99.110  128.151 1.00 35.55  ? 562  LEU B O   1 
ATOM   8270  C CB  . LEU B 1 562 ? 116.043 100.097 126.332 1.00 35.55  ? 562  LEU B CB  1 
ATOM   8271  C CG  . LEU B 1 562 ? 115.251 101.342 125.981 1.00 35.55  ? 562  LEU B CG  1 
ATOM   8272  C CD1 . LEU B 1 562 ? 113.844 100.984 125.555 1.00 35.55  ? 562  LEU B CD1 1 
ATOM   8273  C CD2 . LEU B 1 562 ? 115.251 102.271 127.176 1.00 35.55  ? 562  LEU B CD2 1 
ATOM   8274  N N   . CYS B 1 563 ? 119.028 98.374  126.252 1.00 20.45  ? 563  CYS B N   1 
ATOM   8275  C CA  . CYS B 1 563 ? 119.924 97.447  126.902 1.00 20.45  ? 563  CYS B CA  1 
ATOM   8276  C C   . CYS B 1 563 ? 121.279 98.070  127.180 1.00 20.45  ? 563  CYS B C   1 
ATOM   8277  O O   . CYS B 1 563 ? 122.252 97.346  127.388 1.00 20.45  ? 563  CYS B O   1 
ATOM   8278  C CB  . CYS B 1 563 ? 120.071 96.199  126.046 1.00 20.45  ? 563  CYS B CB  1 
ATOM   8279  S SG  . CYS B 1 563 ? 118.503 95.617  125.417 1.00 20.45  ? 563  CYS B SG  1 
ATOM   8280  N N   . SER B 1 564 ? 121.367 99.392  127.150 1.00 18.68  ? 564  SER B N   1 
ATOM   8281  C CA  . SER B 1 564 ? 122.469 100.126 127.733 1.00 18.68  ? 564  SER B CA  1 
ATOM   8282  C C   . SER B 1 564 ? 122.001 101.049 128.841 1.00 18.68  ? 564  SER B C   1 
ATOM   8283  O O   . SER B 1 564 ? 122.827 101.639 129.540 1.00 18.68  ? 564  SER B O   1 
ATOM   8284  C CB  . SER B 1 564 ? 123.184 100.923 126.658 1.00 18.68  ? 564  SER B CB  1 
ATOM   8285  O OG  . SER B 1 564 ? 123.575 100.045 125.641 1.00 18.68  ? 564  SER B OG  1 
ATOM   8286  N N   . GLN B 1 565 ? 120.698 101.169 129.029 1.00 18.21  ? 565  GLN B N   1 
ATOM   8287  C CA  . GLN B 1 565 ? 120.096 102.018 130.034 1.00 18.21  ? 565  GLN B CA  1 
ATOM   8288  C C   . GLN B 1 565 ? 119.425 101.171 131.090 1.00 18.21  ? 565  GLN B C   1 
ATOM   8289  O O   . GLN B 1 565 ? 118.312 101.449 131.518 1.00 18.21  ? 565  GLN B O   1 
ATOM   8290  C CB  . GLN B 1 565 ? 119.088 102.976 129.412 1.00 18.21  ? 565  GLN B CB  1 
ATOM   8291  C CG  . GLN B 1 565 ? 119.571 103.767 128.220 1.00 18.21  ? 565  GLN B CG  1 
ATOM   8292  C CD  . GLN B 1 565 ? 120.591 104.785 128.585 1.00 18.21  ? 565  GLN B CD  1 
ATOM   8293  O OE1 . GLN B 1 565 ? 120.676 105.204 129.723 1.00 18.21  ? 565  GLN B OE1 1 
ATOM   8294  N NE2 . GLN B 1 565 ? 121.362 105.213 127.623 1.00 18.21  ? 565  GLN B NE2 1 
ATOM   8295  N N   . VAL B 1 566 ? 120.071 100.088 131.485 1.00 18.15  ? 566  VAL B N   1 
ATOM   8296  C CA  . VAL B 1 566 ? 119.654 99.364  132.680 1.00 18.15  ? 566  VAL B CA  1 
ATOM   8297  C C   . VAL B 1 566 ? 120.007 100.149 133.945 1.00 18.15  ? 566  VAL B C   1 
ATOM   8298  O O   . VAL B 1 566 ? 119.161 100.196 134.845 1.00 18.15  ? 566  VAL B O   1 
ATOM   8299  C CB  . VAL B 1 566 ? 120.231 97.942  132.700 1.00 18.15  ? 566  VAL B CB  1 
ATOM   8300  C CG1 . VAL B 1 566 ? 119.602 97.145  133.787 1.00 18.15  ? 566  VAL B CG1 1 
ATOM   8301  C CG2 . VAL B 1 566 ? 119.983 97.277  131.379 1.00 18.15  ? 566  VAL B CG2 1 
ATOM   8302  N N   . PRO B 1 567 ? 121.183 100.791 134.102 1.00 23.76  ? 567  PRO B N   1 
ATOM   8303  C CA  . PRO B 1 567 ? 121.358 101.634 135.296 1.00 23.76  ? 567  PRO B CA  1 
ATOM   8304  C C   . PRO B 1 567 ? 120.544 102.909 135.286 1.00 23.76  ? 567  PRO B C   1 
ATOM   8305  O O   . PRO B 1 567 ? 120.240 103.425 136.363 1.00 23.76  ? 567  PRO B O   1 
ATOM   8306  C CB  . PRO B 1 567 ? 122.854 101.939 135.288 1.00 23.76  ? 567  PRO B CB  1 
ATOM   8307  C CG  . PRO B 1 567 ? 123.426 100.830 134.567 1.00 23.76  ? 567  PRO B CG  1 
ATOM   8308  C CD  . PRO B 1 567 ? 122.503 100.624 133.458 1.00 23.76  ? 567  PRO B CD  1 
ATOM   8309  N N   . MET B 1 568 ? 120.195 103.444 134.126 1.00 35.55  ? 568  MET B N   1 
ATOM   8310  C CA  . MET B 1 568 ? 119.254 104.548 134.074 1.00 35.55  ? 568  MET B CA  1 
ATOM   8311  C C   . MET B 1 568 ? 117.861 104.148 134.527 1.00 35.55  ? 568  MET B C   1 
ATOM   8312  O O   . MET B 1 568 ? 117.165 104.974 135.112 1.00 35.55  ? 568  MET B O   1 
ATOM   8313  C CB  . MET B 1 568 ? 119.193 105.106 132.658 1.00 35.55  ? 568  MET B CB  1 
ATOM   8314  C CG  . MET B 1 568 ? 118.407 106.363 132.498 1.00 35.55  ? 568  MET B CG  1 
ATOM   8315  S SD  . MET B 1 568 ? 116.734 106.072 131.941 1.00 35.55  ? 568  MET B SD  1 
ATOM   8316  C CE  . MET B 1 568 ? 116.868 106.591 130.254 1.00 35.55  ? 568  MET B CE  1 
ATOM   8317  N N   . LEU B 1 569 ? 117.437 102.905 134.317 1.00 17.11  ? 569  LEU B N   1 
ATOM   8318  C CA  . LEU B 1 569 ? 116.080 102.493 134.648 1.00 17.11  ? 569  LEU B CA  1 
ATOM   8319  C C   . LEU B 1 569 ? 115.954 101.996 136.076 1.00 17.11  ? 569  LEU B C   1 
ATOM   8320  O O   . LEU B 1 569 ? 114.931 101.412 136.436 1.00 17.11  ? 569  LEU B O   1 
ATOM   8321  C CB  . LEU B 1 569 ? 115.598 101.426 133.676 1.00 17.11  ? 569  LEU B CB  1 
ATOM   8322  C CG  . LEU B 1 569 ? 115.003 102.047 132.428 1.00 17.11  ? 569  LEU B CG  1 
ATOM   8323  C CD1 . LEU B 1 569 ? 114.852 101.029 131.325 1.00 17.11  ? 569  LEU B CD1 1 
ATOM   8324  C CD2 . LEU B 1 569 ? 113.673 102.642 132.797 1.00 17.11  ? 569  LEU B CD2 1 
ATOM   8325  N N   . ARG B 1 570 ? 116.986 102.190 136.889 1.00 17.20  ? 570  ARG B N   1 
ATOM   8326  C CA  . ARG B 1 570 ? 116.890 102.079 138.336 1.00 17.20  ? 570  ARG B CA  1 
ATOM   8327  C C   . ARG B 1 570 ? 116.784 103.439 138.995 1.00 17.20  ? 570  ARG B C   1 
ATOM   8328  O O   . ARG B 1 570 ? 116.296 103.549 140.120 1.00 17.20  ? 570  ARG B O   1 
ATOM   8329  C CB  . ARG B 1 570 ? 118.108 101.353 138.895 1.00 17.20  ? 570  ARG B CB  1 
ATOM   8330  C CG  . ARG B 1 570 ? 118.420 100.078 138.192 1.00 17.20  ? 570  ARG B CG  1 
ATOM   8331  C CD  . ARG B 1 570 ? 119.292 99.223  139.047 1.00 17.20  ? 570  ARG B CD  1 
ATOM   8332  N NE  . ARG B 1 570 ? 119.529 97.936  138.423 1.00 17.20  ? 570  ARG B NE  1 
ATOM   8333  C CZ  . ARG B 1 570 ? 120.682 97.582  137.885 1.00 17.20  ? 570  ARG B CZ  1 
ATOM   8334  N NH1 . ARG B 1 570 ? 121.700 98.427  137.898 1.00 17.20  ? 570  ARG B NH1 1 
ATOM   8335  N NH2 . ARG B 1 570 ? 120.814 96.390  137.336 1.00 17.20  ? 570  ARG B NH2 1 
ATOM   8336  N N   . ASN B 1 571 ? 117.256 104.472 138.312 1.00 24.78  ? 571  ASN B N   1 
ATOM   8337  C CA  . ASN B 1 571 ? 117.099 105.851 138.736 1.00 24.78  ? 571  ASN B CA  1 
ATOM   8338  C C   . ASN B 1 571 ? 115.908 106.510 138.080 1.00 24.78  ? 571  ASN B C   1 
ATOM   8339  O O   . ASN B 1 571 ? 115.855 107.727 137.961 1.00 24.78  ? 571  ASN B O   1 
ATOM   8340  C CB  . ASN B 1 571 ? 118.374 106.617 138.434 1.00 24.78  ? 571  ASN B CB  1 
ATOM   8341  C CG  . ASN B 1 571 ? 119.592 105.857 138.832 1.00 24.78  ? 571  ASN B CG  1 
ATOM   8342  O OD1 . ASN B 1 571 ? 119.517 104.940 139.636 1.00 24.78  ? 571  ASN B OD1 1 
ATOM   8343  N ND2 . ASN B 1 571 ? 120.730 106.238 138.292 1.00 24.78  ? 571  ASN B ND2 1 
ATOM   8344  N N   . LEU B 1 572 ? 114.943 105.732 137.622 1.00 26.55  ? 572  LEU B N   1 
ATOM   8345  C CA  . LEU B 1 572 ? 113.657 106.271 137.218 1.00 26.55  ? 572  LEU B CA  1 
ATOM   8346  C C   . LEU B 1 572 ? 112.659 105.343 137.877 1.00 26.55  ? 572  LEU B C   1 
ATOM   8347  O O   . LEU B 1 572 ? 111.454 105.402 137.636 1.00 26.55  ? 572  LEU B O   1 
ATOM   8348  C CB  . LEU B 1 572 ? 113.527 106.341 135.695 1.00 26.55  ? 572  LEU B CB  1 
ATOM   8349  C CG  . LEU B 1 572 ? 112.428 107.130 134.972 1.00 26.55  ? 572  LEU B CG  1 
ATOM   8350  C CD1 . LEU B 1 572 ? 112.986 107.717 133.717 1.00 26.55  ? 572  LEU B CD1 1 
ATOM   8351  C CD2 . LEU B 1 572 ? 111.267 106.267 134.567 1.00 26.55  ? 572  LEU B CD2 1 
ATOM   8352  N N   . GLU B 1 573 ? 113.171 104.485 138.735 1.00 21.52  ? 573  GLU B N   1 
ATOM   8353  C CA  . GLU B 1 573 ? 112.331 103.733 139.650 1.00 21.52  ? 573  GLU B CA  1 
ATOM   8354  C C   . GLU B 1 573 ? 112.624 104.044 141.105 1.00 21.52  ? 573  GLU B C   1 
ATOM   8355  O O   . GLU B 1 573 ? 111.809 103.722 141.969 1.00 21.52  ? 573  GLU B O   1 
ATOM   8356  C CB  . GLU B 1 573 ? 112.461 102.229 139.405 1.00 21.52  ? 573  GLU B CB  1 
ATOM   8357  C CG  . GLU B 1 573 ? 111.358 101.659 138.527 1.00 21.52  ? 573  GLU B CG  1 
ATOM   8358  C CD  . GLU B 1 573 ? 109.965 102.048 138.996 1.00 21.52  ? 573  GLU B CD  1 
ATOM   8359  O OE1 . GLU B 1 573 ? 109.350 102.935 138.371 1.00 21.52  ? 573  GLU B OE1 1 
ATOM   8360  O OE2 . GLU B 1 573 ? 109.479 101.462 139.984 1.00 21.52  ? 573  GLU B OE2 1 
ATOM   8361  N N   . TYR B 1 574 ? 113.767 104.648 141.420 1.00 32.92  ? 574  TYR B N   1 
ATOM   8362  C CA  . TYR B 1 574 ? 113.912 105.149 142.777 1.00 32.92  ? 574  TYR B CA  1 
ATOM   8363  C C   . TYR B 1 574 ? 113.168 106.460 142.927 1.00 32.92  ? 574  TYR B C   1 
ATOM   8364  O O   . TYR B 1 574 ? 112.582 106.721 143.982 1.00 32.92  ? 574  TYR B O   1 
ATOM   8365  C CB  . TYR B 1 574 ? 115.362 105.335 143.191 1.00 32.92  ? 574  TYR B CB  1 
ATOM   8366  C CG  . TYR B 1 574 ? 115.414 105.707 144.643 1.00 32.92  ? 574  TYR B CG  1 
ATOM   8367  C CD1 . TYR B 1 574 ? 114.907 104.847 145.605 1.00 32.92  ? 574  TYR B CD1 1 
ATOM   8368  C CD2 . TYR B 1 574 ? 115.907 106.935 145.054 1.00 32.92  ? 574  TYR B CD2 1 
ATOM   8369  C CE1 . TYR B 1 574 ? 114.923 105.181 146.942 1.00 32.92  ? 574  TYR B CE1 1 
ATOM   8370  C CE2 . TYR B 1 574 ? 115.929 107.280 146.394 1.00 32.92  ? 574  TYR B CE2 1 
ATOM   8371  C CZ  . TYR B 1 574 ? 115.432 106.399 147.330 1.00 32.92  ? 574  TYR B CZ  1 
ATOM   8372  O OH  . TYR B 1 574 ? 115.453 106.729 148.664 1.00 32.92  ? 574  TYR B OH  1 
ATOM   8373  N N   . ILE B 1 575 ? 113.197 107.285 141.882 1.00 22.28  ? 575  ILE B N   1 
ATOM   8374  C CA  . ILE B 1 575 ? 112.508 108.566 141.868 1.00 22.28  ? 575  ILE B CA  1 
ATOM   8375  C C   . ILE B 1 575 ? 111.010 108.363 142.009 1.00 22.28  ? 575  ILE B C   1 
ATOM   8376  O O   . ILE B 1 575 ? 110.386 108.949 142.897 1.00 22.28  ? 575  ILE B O   1 
ATOM   8377  C CB  . ILE B 1 575 ? 112.831 109.368 140.603 1.00 22.28  ? 575  ILE B CB  1 
ATOM   8378  C CG1 . ILE B 1 575 ? 114.261 109.873 140.643 1.00 22.28  ? 575  ILE B CG1 1 
ATOM   8379  C CG2 . ILE B 1 575 ? 111.887 110.521 140.451 1.00 22.28  ? 575  ILE B CG2 1 
ATOM   8380  C CD1 . ILE B 1 575 ? 114.624 110.580 139.387 1.00 22.28  ? 575  ILE B CD1 1 
ATOM   8381  N N   . ALA B 1 576 ? 110.422 107.478 141.210 1.00 26.44  ? 576  ALA B N   1 
ATOM   8382  C CA  . ALA B 1 576 ? 108.991 107.245 141.362 1.00 26.44  ? 576  ALA B CA  1 
ATOM   8383  C C   . ALA B 1 576 ? 108.719 106.180 142.418 1.00 26.44  ? 576  ALA B C   1 
ATOM   8384  O O   . ALA B 1 576 ? 107.945 105.245 142.195 1.00 26.44  ? 576  ALA B O   1 
ATOM   8385  C CB  . ALA B 1 576 ? 108.361 106.844 140.030 1.00 26.44  ? 576  ALA B CB  1 
ATOM   8386  N N   . CYS B 1 577 ? 109.362 106.332 143.572 1.00 39.44  ? 577  CYS B N   1 
ATOM   8387  C CA  . CYS B 1 577 ? 109.069 105.665 144.830 1.00 39.44  ? 577  CYS B CA  1 
ATOM   8388  C C   . CYS B 1 577 ? 109.194 106.751 145.888 1.00 39.44  ? 577  CYS B C   1 
ATOM   8389  O O   . CYS B 1 577 ? 108.651 106.655 146.991 1.00 39.44  ? 577  CYS B O   1 
ATOM   8390  C CB  . CYS B 1 577 ? 110.038 104.508 145.075 1.00 39.44  ? 577  CYS B CB  1 
ATOM   8391  S SG  . CYS B 1 577 ? 109.895 103.694 146.680 1.00 39.44  ? 577  CYS B SG  1 
ATOM   8392  N N   . TYR B 1 578 ? 109.927 107.797 145.528 1.00 46.32  ? 578  TYR B N   1 
ATOM   8393  C CA  . TYR B 1 578 ? 110.192 108.943 146.379 1.00 46.32  ? 578  TYR B CA  1 
ATOM   8394  C C   . TYR B 1 578 ? 109.275 110.085 145.946 1.00 46.32  ? 578  TYR B C   1 
ATOM   8395  O O   . TYR B 1 578 ? 109.433 111.229 146.378 1.00 46.32  ? 578  TYR B O   1 
ATOM   8396  C CB  . TYR B 1 578 ? 111.683 109.288 146.264 1.00 46.32  ? 578  TYR B CB  1 
ATOM   8397  C CG  . TYR B 1 578 ? 112.216 110.287 147.249 1.00 46.32  ? 578  TYR B CG  1 
ATOM   8398  C CD1 . TYR B 1 578 ? 112.417 109.938 148.572 1.00 46.32  ? 578  TYR B CD1 1 
ATOM   8399  C CD2 . TYR B 1 578 ? 112.551 111.573 146.848 1.00 46.32  ? 578  TYR B CD2 1 
ATOM   8400  C CE1 . TYR B 1 578 ? 112.909 110.848 149.481 1.00 46.32  ? 578  TYR B CE1 1 
ATOM   8401  C CE2 . TYR B 1 578 ? 113.043 112.494 147.752 1.00 46.32  ? 578  TYR B CE2 1 
ATOM   8402  C CZ  . TYR B 1 578 ? 113.218 112.124 149.070 1.00 46.32  ? 578  TYR B CZ  1 
ATOM   8403  O OH  . TYR B 1 578 ? 113.710 113.037 149.978 1.00 46.32  ? 578  TYR B OH  1 
ATOM   8404  N N   . TYR B 1 579 ? 108.317 109.785 145.071 1.00 42.95  ? 579  TYR B N   1 
ATOM   8405  C CA  . TYR B 1 579 ? 107.395 110.793 144.560 1.00 42.95  ? 579  TYR B CA  1 
ATOM   8406  C C   . TYR B 1 579 ? 105.993 110.215 144.388 1.00 42.95  ? 579  TYR B C   1 
ATOM   8407  O O   . TYR B 1 579 ? 105.101 110.880 143.854 1.00 42.95  ? 579  TYR B O   1 
ATOM   8408  C CB  . TYR B 1 579 ? 107.935 111.354 143.238 1.00 42.95  ? 579  TYR B CB  1 
ATOM   8409  C CG  . TYR B 1 579 ? 107.263 112.604 142.714 1.00 42.95  ? 579  TYR B CG  1 
ATOM   8410  C CD1 . TYR B 1 579 ? 106.743 112.644 141.424 1.00 42.95  ? 579  TYR B CD1 1 
ATOM   8411  C CD2 . TYR B 1 579 ? 107.136 113.732 143.506 1.00 42.95  ? 579  TYR B CD2 1 
ATOM   8412  C CE1 . TYR B 1 579 ? 106.125 113.782 140.935 1.00 42.95  ? 579  TYR B CE1 1 
ATOM   8413  C CE2 . TYR B 1 579 ? 106.516 114.876 143.029 1.00 42.95  ? 579  TYR B CE2 1 
ATOM   8414  C CZ  . TYR B 1 579 ? 106.014 114.894 141.745 1.00 42.95  ? 579  TYR B CZ  1 
ATOM   8415  O OH  . TYR B 1 579 ? 105.400 116.031 141.275 1.00 42.95  ? 579  TYR B OH  1 
ATOM   8416  N N   . ILE B 1 580 ? 105.768 108.979 144.828 1.00 40.57  ? 580  ILE B N   1 
ATOM   8417  C CA  . ILE B 1 580 ? 104.477 108.351 144.560 1.00 40.57  ? 580  ILE B CA  1 
ATOM   8418  C C   . ILE B 1 580 ? 103.883 107.738 145.822 1.00 40.57  ? 580  ILE B C   1 
ATOM   8419  O O   . ILE B 1 580 ? 102.695 107.399 145.855 1.00 40.57  ? 580  ILE B O   1 
ATOM   8420  C CB  . ILE B 1 580 ? 104.594 107.309 143.428 1.00 40.57  ? 580  ILE B CB  1 
ATOM   8421  C CG1 . ILE B 1 580 ? 103.276 107.193 142.656 1.00 40.57  ? 580  ILE B CG1 1 
ATOM   8422  C CG2 . ILE B 1 580 ? 105.019 105.946 143.958 1.00 40.57  ? 580  ILE B CG2 1 
ATOM   8423  C CD1 . ILE B 1 580 ? 102.922 108.421 141.854 1.00 40.57  ? 580  ILE B CD1 1 
ATOM   8424  N N   . THR B 1 581 ? 104.678 107.605 146.878 1.00 43.12  ? 581  THR B N   1 
ATOM   8425  C CA  . THR B 1 581 ? 104.162 107.039 148.120 1.00 43.12  ? 581  THR B CA  1 
ATOM   8426  C C   . THR B 1 581 ? 104.467 107.963 149.293 1.00 43.12  ? 581  THR B C   1 
ATOM   8427  O O   . THR B 1 581 ? 104.240 107.637 150.462 1.00 43.12  ? 581  THR B O   1 
ATOM   8428  C CB  . THR B 1 581 ? 104.700 105.622 148.335 1.00 43.12  ? 581  THR B CB  1 
ATOM   8429  O OG1 . THR B 1 581 ? 103.884 104.938 149.293 1.00 43.12  ? 581  THR B OG1 1 
ATOM   8430  C CG2 . THR B 1 581 ? 106.144 105.629 148.809 1.00 43.12  ? 581  THR B CG2 1 
ATOM   8431  N N   . GLY B 1 582 ? 104.920 109.173 148.982 1.00 52.15  ? 582  GLY B N   1 
ATOM   8432  C CA  . GLY B 1 582 ? 105.148 110.167 150.010 1.00 52.15  ? 582  GLY B CA  1 
ATOM   8433  C C   . GLY B 1 582 ? 106.351 109.884 150.882 1.00 52.15  ? 582  GLY B C   1 
ATOM   8434  O O   . GLY B 1 582 ? 106.208 109.534 152.056 1.00 52.15  ? 582  GLY B O   1 
ATOM   8435  N N   . SER B 1 583 ? 107.545 110.009 150.308 1.00 55.58  ? 583  SER B N   1 
ATOM   8436  C CA  . SER B 1 583 ? 108.781 109.825 151.051 1.00 55.58  ? 583  SER B CA  1 
ATOM   8437  C C   . SER B 1 583 ? 109.598 111.107 151.113 1.00 55.58  ? 583  SER B C   1 
ATOM   8438  O O   . SER B 1 583 ? 110.689 111.106 151.692 1.00 55.58  ? 583  SER B O   1 
ATOM   8439  C CB  . SER B 1 583 ? 109.615 108.705 150.429 1.00 55.58  ? 583  SER B CB  1 
ATOM   8440  O OG  . SER B 1 583 ? 108.955 107.462 150.552 1.00 55.58  ? 583  SER B OG  1 
ATOM   8441  N N   . TYR B 1 584 ? 109.092 112.196 150.541 1.00 52.68  ? 584  TYR B N   1 
ATOM   8442  C CA  . TYR B 1 584 ? 109.825 113.450 150.438 1.00 52.68  ? 584  TYR B CA  1 
ATOM   8443  C C   . TYR B 1 584 ? 109.424 114.413 151.548 1.00 52.68  ? 584  TYR B C   1 
ATOM   8444  O O   . TYR B 1 584 ? 110.283 115.030 152.184 1.00 52.68  ? 584  TYR B O   1 
ATOM   8445  C CB  . TYR B 1 584 ? 109.619 114.093 149.055 1.00 52.68  ? 584  TYR B CB  1 
ATOM   8446  C CG  . TYR B 1 584 ? 108.188 114.410 148.622 1.00 52.68  ? 584  TYR B CG  1 
ATOM   8447  C CD1 . TYR B 1 584 ? 107.300 113.407 148.242 1.00 52.68  ? 584  TYR B CD1 1 
ATOM   8448  C CD2 . TYR B 1 584 ? 107.749 115.723 148.543 1.00 52.68  ? 584  TYR B CD2 1 
ATOM   8449  C CE1 . TYR B 1 584 ? 106.017 113.701 147.836 1.00 52.68  ? 584  TYR B CE1 1 
ATOM   8450  C CE2 . TYR B 1 584 ? 106.463 116.025 148.132 1.00 52.68  ? 584  TYR B CE2 1 
ATOM   8451  C CZ  . TYR B 1 584 ? 105.606 115.009 147.780 1.00 52.68  ? 584  TYR B CZ  1 
ATOM   8452  O OH  . TYR B 1 584 ? 104.329 115.300 147.371 1.00 52.68  ? 584  TYR B OH  1 
ATOM   8453  N N   . ALA B 1 585 ? 108.124 114.545 151.791 1.00 55.50  ? 585  ALA B N   1 
ATOM   8454  C CA  . ALA B 1 585 ? 107.642 115.419 152.851 1.00 55.50  ? 585  ALA B CA  1 
ATOM   8455  C C   . ALA B 1 585 ? 107.806 114.751 154.208 1.00 55.50  ? 585  ALA B C   1 
ATOM   8456  O O   . ALA B 1 585 ? 107.824 115.426 155.241 1.00 55.50  ? 585  ALA B O   1 
ATOM   8457  C CB  . ALA B 1 585 ? 106.179 115.796 152.614 1.00 55.50  ? 585  ALA B CB  1 
ATOM   8458  N N   . THR B 1 586 ? 107.916 113.424 154.213 1.00 56.14  ? 586  THR B N   1 
ATOM   8459  C CA  . THR B 1 586 ? 107.999 112.672 155.458 1.00 56.14  ? 586  THR B CA  1 
ATOM   8460  C C   . THR B 1 586 ? 109.444 112.437 155.887 1.00 56.14  ? 586  THR B C   1 
ATOM   8461  O O   . THR B 1 586 ? 109.685 111.810 156.926 1.00 56.14  ? 586  THR B O   1 
ATOM   8462  C CB  . THR B 1 586 ? 107.260 111.344 155.314 1.00 56.14  ? 586  THR B CB  1 
ATOM   8463  O OG1 . THR B 1 586 ? 108.009 110.467 154.464 1.00 56.14  ? 586  THR B OG1 1 
ATOM   8464  C CG2 . THR B 1 586 ? 105.890 111.580 154.709 1.00 56.14  ? 586  THR B CG2 1 
ATOM   8465  N N   . GLN B 1 587 ? 110.393 112.925 155.078 1.00 57.73  ? 587  GLN B N   1 
ATOM   8466  C CA  . GLN B 1 587 ? 111.825 112.968 155.379 1.00 57.73  ? 587  GLN B CA  1 
ATOM   8467  C C   . GLN B 1 587 ? 112.444 111.608 155.676 1.00 57.73  ? 587  GLN B C   1 
ATOM   8468  O O   . GLN B 1 587 ? 112.876 111.358 156.805 1.00 57.73  ? 587  GLN B O   1 
ATOM   8469  C CB  . GLN B 1 587 ? 112.101 113.902 156.562 1.00 57.73  ? 587  GLN B CB  1 
ATOM   8470  C CG  . GLN B 1 587 ? 112.096 115.408 156.292 1.00 57.73  ? 587  GLN B CG  1 
ATOM   8471  C CD  . GLN B 1 587 ? 113.330 115.937 155.562 1.00 57.73  ? 587  GLN B CD  1 
ATOM   8472  O OE1 . GLN B 1 587 ? 113.828 115.347 154.608 1.00 57.73  ? 587  GLN B OE1 1 
ATOM   8473  N NE2 . GLN B 1 587 ? 113.856 117.044 156.061 1.00 57.73  ? 587  GLN B NE2 1 
ATOM   8474  N N   . ASP B 1 588 ? 112.497 110.727 154.681 1.00 60.77  ? 588  ASP B N   1 
ATOM   8475  C CA  . ASP B 1 588 ? 113.112 109.419 154.867 1.00 60.77  ? 588  ASP B CA  1 
ATOM   8476  C C   . ASP B 1 588 ? 113.700 108.877 153.568 1.00 60.77  ? 588  ASP B C   1 
ATOM   8477  O O   . ASP B 1 588 ? 112.970 108.583 152.618 1.00 60.77  ? 588  ASP B O   1 
ATOM   8478  C CB  . ASP B 1 588 ? 112.095 108.445 155.468 1.00 60.77  ? 588  ASP B CB  1 
ATOM   8479  C CG  . ASP B 1 588 ? 111.771 108.754 156.922 1.00 60.77  ? 588  ASP B CG  1 
ATOM   8480  O OD1 . ASP B 1 588 ? 112.513 109.523 157.562 1.00 60.77  ? 588  ASP B OD1 1 
ATOM   8481  O OD2 . ASP B 1 588 ? 110.765 108.214 157.430 1.00 60.77  ? 588  ASP B OD2 1 
ATOM   8482  N N   . TYR B 1 589 ? 115.030 108.740 153.519 1.00 55.86  ? 589  TYR B N   1 
ATOM   8483  C CA  . TYR B 1 589 ? 115.727 108.249 152.335 1.00 55.86  ? 589  TYR B CA  1 
ATOM   8484  C C   . TYR B 1 589 ? 115.809 106.729 152.291 1.00 55.86  ? 589  TYR B C   1 
ATOM   8485  O O   . TYR B 1 589 ? 116.399 106.167 151.359 1.00 55.86  ? 589  TYR B O   1 
ATOM   8486  C CB  . TYR B 1 589 ? 117.126 108.864 152.250 1.00 55.86  ? 589  TYR B CB  1 
ATOM   8487  C CG  . TYR B 1 589 ? 117.878 108.927 153.563 1.00 55.86  ? 589  TYR B CG  1 
ATOM   8488  C CD1 . TYR B 1 589 ? 118.028 110.127 154.241 1.00 55.86  ? 589  TYR B CD1 1 
ATOM   8489  C CD2 . TYR B 1 589 ? 118.474 107.797 154.100 1.00 55.86  ? 589  TYR B CD2 1 
ATOM   8490  C CE1 . TYR B 1 589 ? 118.720 110.194 155.434 1.00 55.86  ? 589  TYR B CE1 1 
ATOM   8491  C CE2 . TYR B 1 589 ? 119.169 107.851 155.293 1.00 55.86  ? 589  TYR B CE2 1 
ATOM   8492  C CZ  . TYR B 1 589 ? 119.290 109.052 155.953 1.00 55.86  ? 589  TYR B CZ  1 
ATOM   8493  O OH  . TYR B 1 589 ? 119.984 109.109 157.138 1.00 55.86  ? 589  TYR B OH  1 
ATOM   8494  N N   . GLU B 1 590 ? 115.231 106.046 153.276 1.00 57.62  ? 590  GLU B N   1 
ATOM   8495  C CA  . GLU B 1 590 ? 115.238 104.590 153.261 1.00 57.62  ? 590  GLU B CA  1 
ATOM   8496  C C   . GLU B 1 590 ? 113.838 103.996 153.189 1.00 57.62  ? 590  GLU B C   1 
ATOM   8497  O O   . GLU B 1 590 ? 113.691 102.808 153.490 1.00 57.62  ? 590  GLU B O   1 
ATOM   8498  C CB  . GLU B 1 590 ? 115.946 104.033 154.503 1.00 57.62  ? 590  GLU B CB  1 
ATOM   8499  C CG  . GLU B 1 590 ? 117.406 104.422 154.641 1.00 57.62  ? 590  GLU B CG  1 
ATOM   8500  C CD  . GLU B 1 590 ? 118.327 103.580 153.783 1.00 57.62  ? 590  GLU B CD  1 
ATOM   8501  O OE1 . GLU B 1 590 ? 118.287 102.339 153.909 1.00 57.62  ? 590  GLU B OE1 1 
ATOM   8502  O OE2 . GLU B 1 590 ? 119.097 104.161 152.991 1.00 57.62  ? 590  GLU B OE2 1 
ATOM   8503  N N   . TYR B 1 591 ? 112.812 104.766 152.814 1.00 60.04  ? 591  TYR B N   1 
ATOM   8504  C CA  . TYR B 1 591 ? 111.443 104.258 152.844 1.00 60.04  ? 591  TYR B CA  1 
ATOM   8505  C C   . TYR B 1 591 ? 111.217 103.205 151.768 1.00 60.04  ? 591  TYR B C   1 
ATOM   8506  O O   . TYR B 1 591 ? 110.400 102.293 151.937 1.00 60.04  ? 591  TYR B O   1 
ATOM   8507  C CB  . TYR B 1 591 ? 110.450 105.408 152.683 1.00 60.04  ? 591  TYR B CB  1 
ATOM   8508  C CG  . TYR B 1 591 ? 109.011 105.013 152.933 1.00 60.04  ? 591  TYR B CG  1 
ATOM   8509  C CD1 . TYR B 1 591 ? 108.167 104.667 151.882 1.00 60.04  ? 591  TYR B CD1 1 
ATOM   8510  C CD2 . TYR B 1 591 ? 108.498 104.980 154.223 1.00 60.04  ? 591  TYR B CD2 1 
ATOM   8511  C CE1 . TYR B 1 591 ? 106.855 104.304 152.110 1.00 60.04  ? 591  TYR B CE1 1 
ATOM   8512  C CE2 . TYR B 1 591 ? 107.184 104.619 154.461 1.00 60.04  ? 591  TYR B CE2 1 
ATOM   8513  C CZ  . TYR B 1 591 ? 106.369 104.282 153.400 1.00 60.04  ? 591  TYR B CZ  1 
ATOM   8514  O OH  . TYR B 1 591 ? 105.062 103.923 153.630 1.00 60.04  ? 591  TYR B OH  1 
ATOM   8515  N N   . CYS B 1 592 ? 111.924 103.320 150.649 1.00 55.51  ? 592  CYS B N   1 
ATOM   8516  C CA  . CYS B 1 592 ? 111.815 102.322 149.596 1.00 55.51  ? 592  CYS B CA  1 
ATOM   8517  C C   . CYS B 1 592 ? 112.570 101.053 149.967 1.00 55.51  ? 592  CYS B C   1 
ATOM   8518  O O   . CYS B 1 592 ? 112.029 99.949  149.853 1.00 55.51  ? 592  CYS B O   1 
ATOM   8519  C CB  . CYS B 1 592 ? 112.330 102.884 148.271 1.00 55.51  ? 592  CYS B CB  1 
ATOM   8520  S SG  . CYS B 1 592 ? 111.488 104.385 147.731 1.00 55.51  ? 592  CYS B SG  1 
ATOM   8521  N N   . MET B 1 593 ? 113.815 101.197 150.421 1.00 51.89  ? 593  MET B N   1 
ATOM   8522  C CA  . MET B 1 593 ? 114.680 100.043 150.638 1.00 51.89  ? 593  MET B CA  1 
ATOM   8523  C C   . MET B 1 593 ? 114.579 99.450  152.045 1.00 51.89  ? 593  MET B C   1 
ATOM   8524  O O   . MET B 1 593 ? 115.594 99.207  152.708 1.00 51.89  ? 593  MET B O   1 
ATOM   8525  C CB  . MET B 1 593 ? 116.121 100.425 150.274 1.00 51.89  ? 593  MET B CB  1 
ATOM   8526  C CG  . MET B 1 593 ? 116.673 101.667 150.957 1.00 51.89  ? 593  MET B CG  1 
ATOM   8527  S SD  . MET B 1 593 ? 118.342 102.053 150.392 1.00 51.89  ? 593  MET B SD  1 
ATOM   8528  C CE  . MET B 1 593 ? 119.291 100.729 151.137 1.00 51.89  ? 593  MET B CE  1 
ATOM   8529  N N   . ARG B 1 594 ? 113.354 99.168  152.491 1.00 57.93  ? 594  ARG B N   1 
ATOM   8530  C CA  . ARG B 1 594 ? 113.136 98.381  153.701 1.00 57.93  ? 594  ARG B CA  1 
ATOM   8531  C C   . ARG B 1 594 ? 112.451 97.068  153.355 1.00 57.93  ? 594  ARG B C   1 
ATOM   8532  O O   . ARG B 1 594 ? 112.915 95.989  153.736 1.00 57.93  ? 594  ARG B O   1 
ATOM   8533  C CB  . ARG B 1 594 ? 112.281 99.141  154.719 1.00 57.93  ? 594  ARG B CB  1 
ATOM   8534  C CG  . ARG B 1 594 ? 112.964 100.316 155.371 1.00 57.93  ? 594  ARG B CG  1 
ATOM   8535  C CD  . ARG B 1 594 ? 111.994 101.117 156.221 1.00 57.93  ? 594  ARG B CD  1 
ATOM   8536  N NE  . ARG B 1 594 ? 112.428 102.503 156.373 1.00 57.93  ? 594  ARG B NE  1 
ATOM   8537  C CZ  . ARG B 1 594 ? 113.248 102.934 157.325 1.00 57.93  ? 594  ARG B CZ  1 
ATOM   8538  N NH1 . ARG B 1 594 ? 113.732 102.088 158.222 1.00 57.93  ? 594  ARG B NH1 1 
ATOM   8539  N NH2 . ARG B 1 594 ? 113.584 104.215 157.378 1.00 57.93  ? 594  ARG B NH2 1 
ATOM   8540  N N   . VAL B 1 595 ? 111.343 97.163  152.627 1.00 54.42  ? 595  VAL B N   1 
ATOM   8541  C CA  . VAL B 1 595 ? 110.505 96.021  152.288 1.00 54.42  ? 595  VAL B CA  1 
ATOM   8542  C C   . VAL B 1 595 ? 111.107 95.255  151.119 1.00 54.42  ? 595  VAL B C   1 
ATOM   8543  O O   . VAL B 1 595 ? 112.099 95.687  150.522 1.00 54.42  ? 595  VAL B O   1 
ATOM   8544  C CB  . VAL B 1 595 ? 109.067 96.472  151.977 1.00 54.42  ? 595  VAL B CB  1 
ATOM   8545  C CG1 . VAL B 1 595 ? 108.316 96.760  153.264 1.00 54.42  ? 595  VAL B CG1 1 
ATOM   8546  C CG2 . VAL B 1 595 ? 109.091 97.713  151.107 1.00 54.42  ? 595  VAL B CG2 1 
ATOM   8547  N N   . LYS B 1 596 ? 110.517 94.099  150.802 1.00 52.90  ? 596  LYS B N   1 
ATOM   8548  C CA  . LYS B 1 596 ? 110.935 93.224  149.707 1.00 52.90  ? 596  LYS B CA  1 
ATOM   8549  C C   . LYS B 1 596 ? 110.838 93.874  148.329 1.00 52.90  ? 596  LYS B C   1 
ATOM   8550  O O   . LYS B 1 596 ? 111.427 93.376  147.364 1.00 52.90  ? 596  LYS B O   1 
ATOM   8551  C CB  . LYS B 1 596 ? 110.083 91.954  149.719 1.00 52.90  ? 596  LYS B CB  1 
ATOM   8552  C CG  . LYS B 1 596 ? 108.590 92.231  149.570 1.00 52.90  ? 596  LYS B CG  1 
ATOM   8553  C CD  . LYS B 1 596 ? 107.741 91.040  149.981 1.00 52.90  ? 596  LYS B CD  1 
ATOM   8554  C CE  . LYS B 1 596 ? 107.385 90.169  148.786 1.00 52.90  ? 596  LYS B CE  1 
ATOM   8555  N NZ  . LYS B 1 596 ? 106.919 88.818  149.203 1.00 52.90  ? 596  LYS B NZ  1 
ATOM   8556  N N   . TYR B 1 597 ? 110.058 94.952  148.234 1.00 49.16  ? 597  TYR B N   1 
ATOM   8557  C CA  . TYR B 1 597 ? 109.897 95.806  147.063 1.00 49.16  ? 597  TYR B CA  1 
ATOM   8558  C C   . TYR B 1 597 ? 111.235 96.264  146.491 1.00 49.16  ? 597  TYR B C   1 
ATOM   8559  O O   . TYR B 1 597 ? 111.411 96.279  145.271 1.00 49.16  ? 597  TYR B O   1 
ATOM   8560  C CB  . TYR B 1 597 ? 108.993 96.981  147.453 1.00 49.16  ? 597  TYR B CB  1 
ATOM   8561  C CG  . TYR B 1 597 ? 108.688 98.012  146.394 1.00 49.16  ? 597  TYR B CG  1 
ATOM   8562  C CD1 . TYR B 1 597 ? 107.971 97.679  145.253 1.00 49.16  ? 597  TYR B CD1 1 
ATOM   8563  C CD2 . TYR B 1 597 ? 109.020 99.347  146.593 1.00 49.16  ? 597  TYR B CD2 1 
ATOM   8564  C CE1 . TYR B 1 597 ? 107.665 98.634  144.299 1.00 49.16  ? 597  TYR B CE1 1 
ATOM   8565  C CE2 . TYR B 1 597 ? 108.713 100.309 145.648 1.00 49.16  ? 597  TYR B CE2 1 
ATOM   8566  C CZ  . TYR B 1 597 ? 108.037 99.946  144.502 1.00 49.16  ? 597  TYR B CZ  1 
ATOM   8567  O OH  . TYR B 1 597 ? 107.725 100.897 143.556 1.00 49.16  ? 597  TYR B OH  1 
ATOM   8568  N N   . TYR B 1 598 ? 112.182 96.643  147.346 1.00 46.45  ? 598  TYR B N   1 
ATOM   8569  C CA  . TYR B 1 598 ? 113.496 97.025  146.842 1.00 46.45  ? 598  TYR B CA  1 
ATOM   8570  C C   . TYR B 1 598 ? 114.560 95.985  147.128 1.00 46.45  ? 598  TYR B C   1 
ATOM   8571  O O   . TYR B 1 598 ? 115.719 96.324  147.387 1.00 46.45  ? 598  TYR B O   1 
ATOM   8572  C CB  . TYR B 1 598 ? 113.927 98.370  147.402 1.00 46.45  ? 598  TYR B CB  1 
ATOM   8573  C CG  . TYR B 1 598 ? 113.648 99.450  146.413 1.00 46.45  ? 598  TYR B CG  1 
ATOM   8574  C CD1 . TYR B 1 598 ? 114.640 100.321 145.991 1.00 46.45  ? 598  TYR B CD1 1 
ATOM   8575  C CD2 . TYR B 1 598 ? 112.388 99.565  145.860 1.00 46.45  ? 598  TYR B CD2 1 
ATOM   8576  C CE1 . TYR B 1 598 ? 114.360 101.297 145.063 1.00 46.45  ? 598  TYR B CE1 1 
ATOM   8577  C CE2 . TYR B 1 598 ? 112.102 100.522 144.946 1.00 46.45  ? 598  TYR B CE2 1 
ATOM   8578  C CZ  . TYR B 1 598 ? 113.078 101.377 144.550 1.00 46.45  ? 598  TYR B CZ  1 
ATOM   8579  O OH  . TYR B 1 598 ? 112.723 102.309 143.629 1.00 46.45  ? 598  TYR B OH  1 
ATOM   8580  N N   . ARG B 1 599 ? 114.175 94.717  147.098 1.00 48.23  ? 599  ARG B N   1 
ATOM   8581  C CA  . ARG B 1 599 ? 115.135 93.627  147.071 1.00 48.23  ? 599  ARG B CA  1 
ATOM   8582  C C   . ARG B 1 599 ? 115.070 92.857  145.760 1.00 48.23  ? 599  ARG B C   1 
ATOM   8583  O O   . ARG B 1 599 ? 116.106 92.412  145.257 1.00 48.23  ? 599  ARG B O   1 
ATOM   8584  C CB  . ARG B 1 599 ? 114.908 92.701  148.266 1.00 48.23  ? 599  ARG B CB  1 
ATOM   8585  C CG  . ARG B 1 599 ? 115.136 93.391  149.600 1.00 48.23  ? 599  ARG B CG  1 
ATOM   8586  C CD  . ARG B 1 599 ? 114.975 92.439  150.770 1.00 48.23  ? 599  ARG B CD  1 
ATOM   8587  N NE  . ARG B 1 599 ? 116.050 91.452  150.815 1.00 48.23  ? 599  ARG B NE  1 
ATOM   8588  C CZ  . ARG B 1 599 ? 116.090 90.426  151.659 1.00 48.23  ? 599  ARG B CZ  1 
ATOM   8589  N NH1 . ARG B 1 599 ? 115.114 90.249  152.539 1.00 48.23  ? 599  ARG B NH1 1 
ATOM   8590  N NH2 . ARG B 1 599 ? 117.110 89.579  151.627 1.00 48.23  ? 599  ARG B NH2 1 
ATOM   8591  N N   . ASP B 1 600 ? 113.877 92.699  145.192 1.00 40.02  ? 600  ASP B N   1 
ATOM   8592  C CA  . ASP B 1 600 ? 113.724 92.045  143.902 1.00 40.02  ? 600  ASP B CA  1 
ATOM   8593  C C   . ASP B 1 600 ? 113.080 92.983  142.892 1.00 40.02  ? 600  ASP B C   1 
ATOM   8594  O O   . ASP B 1 600 ? 113.609 93.175  141.797 1.00 40.02  ? 600  ASP B O   1 
ATOM   8595  C CB  . ASP B 1 600 ? 112.892 90.768  144.047 1.00 40.02  ? 600  ASP B CB  1 
ATOM   8596  C CG  . ASP B 1 600 ? 113.319 89.673  143.082 1.00 40.02  ? 600  ASP B CG  1 
ATOM   8597  O OD1 . ASP B 1 600 ? 112.536 88.718  142.879 1.00 40.02  ? 600  ASP B OD1 1 
ATOM   8598  O OD2 . ASP B 1 600 ? 114.435 89.762  142.525 1.00 40.02  ? 600  ASP B OD2 1 
ATOM   8599  N N   . LEU B 1 601 ? 111.970 93.618  143.264 1.00 30.80  ? 601  LEU B N   1 
ATOM   8600  C CA  . LEU B 1 601 ? 111.133 94.308  142.287 1.00 30.80  ? 601  LEU B CA  1 
ATOM   8601  C C   . LEU B 1 601 ? 111.655 95.690  141.910 1.00 30.80  ? 601  LEU B C   1 
ATOM   8602  O O   . LEU B 1 601 ? 110.998 96.418  141.165 1.00 30.80  ? 601  LEU B O   1 
ATOM   8603  C CB  . LEU B 1 601 ? 109.692 94.421  142.791 1.00 30.80  ? 601  LEU B CB  1 
ATOM   8604  C CG  . LEU B 1 601 ? 108.755 93.224  142.579 1.00 30.80  ? 601  LEU B CG  1 
ATOM   8605  C CD1 . LEU B 1 601 ? 109.021 92.076  143.545 1.00 30.80  ? 601  LEU B CD1 1 
ATOM   8606  C CD2 . LEU B 1 601 ? 107.301 93.663  142.655 1.00 30.80  ? 601  LEU B CD2 1 
ATOM   8607  N N   . ALA B 1 602 ? 112.799 96.076  142.437 1.00 31.56  ? 602  ALA B N   1 
ATOM   8608  C CA  . ALA B 1 602 ? 113.548 97.175  141.846 1.00 31.56  ? 602  ALA B CA  1 
ATOM   8609  C C   . ALA B 1 602 ? 114.803 96.679  141.160 1.00 31.56  ? 602  ALA B C   1 
ATOM   8610  O O   . ALA B 1 602 ? 115.663 97.492  140.817 1.00 31.56  ? 602  ALA B O   1 
ATOM   8611  C CB  . ALA B 1 602 ? 113.917 98.216  142.898 1.00 31.56  ? 602  ALA B CB  1 
ATOM   8612  N N   . TYR B 1 603 ? 114.944 95.374  140.984 1.00 30.30  ? 603  TYR B N   1 
ATOM   8613  C CA  . TYR B 1 603 ? 116.050 94.767  140.278 1.00 30.30  ? 603  TYR B CA  1 
ATOM   8614  C C   . TYR B 1 603 ? 115.557 93.726  139.286 1.00 30.30  ? 603  TYR B C   1 
ATOM   8615  O O   . TYR B 1 603 ? 116.265 93.423  138.321 1.00 30.30  ? 603  TYR B O   1 
ATOM   8616  C CB  . TYR B 1 603 ? 117.019 94.135  141.283 1.00 30.30  ? 603  TYR B CB  1 
ATOM   8617  C CG  . TYR B 1 603 ? 118.263 93.558  140.681 1.00 30.30  ? 603  TYR B CG  1 
ATOM   8618  C CD1 . TYR B 1 603 ? 118.582 92.224  140.863 1.00 30.30  ? 603  TYR B CD1 1 
ATOM   8619  C CD2 . TYR B 1 603 ? 119.121 94.344  139.938 1.00 30.30  ? 603  TYR B CD2 1 
ATOM   8620  C CE1 . TYR B 1 603 ? 119.716 91.693  140.323 1.00 30.30  ? 603  TYR B CE1 1 
ATOM   8621  C CE2 . TYR B 1 603 ? 120.258 93.822  139.396 1.00 30.30  ? 603  TYR B CE2 1 
ATOM   8622  C CZ  . TYR B 1 603 ? 120.548 92.496  139.591 1.00 30.30  ? 603  TYR B CZ  1 
ATOM   8623  O OH  . TYR B 1 603 ? 121.682 91.962  139.049 1.00 30.30  ? 603  TYR B OH  1 
ATOM   8624  N N   . ALA B 1 604 ? 114.352 93.194  139.480 1.00 31.29  ? 604  ALA B N   1 
ATOM   8625  C CA  . ALA B 1 604 ? 113.775 92.238  138.549 1.00 31.29  ? 604  ALA B CA  1 
ATOM   8626  C C   . ALA B 1 604 ? 113.005 92.953  137.453 1.00 31.29  ? 604  ALA B C   1 
ATOM   8627  O O   . ALA B 1 604 ? 112.919 92.452  136.331 1.00 31.29  ? 604  ALA B O   1 
ATOM   8628  C CB  . ALA B 1 604 ? 112.855 91.252  139.265 1.00 31.29  ? 604  ALA B CB  1 
ATOM   8629  N N   . VAL B 1 605 ? 112.431 94.114  137.754 1.00 24.57  ? 605  VAL B N   1 
ATOM   8630  C CA  . VAL B 1 605 ? 111.775 94.884  136.706 1.00 24.57  ? 605  VAL B CA  1 
ATOM   8631  C C   . VAL B 1 605 ? 112.831 95.815  136.131 1.00 24.57  ? 605  VAL B C   1 
ATOM   8632  O O   . VAL B 1 605 ? 112.586 96.541  135.163 1.00 24.57  ? 605  VAL B O   1 
ATOM   8633  C CB  . VAL B 1 605 ? 110.544 95.651  137.223 1.00 24.57  ? 605  VAL B CB  1 
ATOM   8634  C CG1 . VAL B 1 605 ? 110.953 96.915  137.953 1.00 24.57  ? 605  VAL B CG1 1 
ATOM   8635  C CG2 . VAL B 1 605 ? 109.553 95.932  136.098 1.00 24.57  ? 605  VAL B CG2 1 
ATOM   8636  N N   . SER B 1 606 ? 114.021 95.807  136.724 1.00 19.94  ? 606  SER B N   1 
ATOM   8637  C CA  . SER B 1 606 ? 115.142 96.457  136.077 1.00 19.94  ? 606  SER B CA  1 
ATOM   8638  C C   . SER B 1 606 ? 115.574 95.723  134.819 1.00 19.94  ? 606  SER B C   1 
ATOM   8639  O O   . SER B 1 606 ? 116.054 96.371  133.887 1.00 19.94  ? 606  SER B O   1 
ATOM   8640  C CB  . SER B 1 606 ? 116.312 96.576  137.039 1.00 19.94  ? 606  SER B CB  1 
ATOM   8641  O OG  . SER B 1 606 ? 117.506 96.835  136.342 1.00 19.94  ? 606  SER B OG  1 
ATOM   8642  N N   . PHE B 1 607 ? 115.409 94.398  134.762 1.00 25.53  ? 607  PHE B N   1 
ATOM   8643  C CA  . PHE B 1 607 ? 115.582 93.643  133.515 1.00 25.53  ? 607  PHE B CA  1 
ATOM   8644  C C   . PHE B 1 607 ? 114.270 93.457  132.789 1.00 25.53  ? 607  PHE B C   1 
ATOM   8645  O O   . PHE B 1 607 ? 113.903 92.368  132.367 1.00 25.53  ? 607  PHE B O   1 
ATOM   8646  C CB  . PHE B 1 607 ? 116.213 92.295  133.794 1.00 25.53  ? 607  PHE B CB  1 
ATOM   8647  C CG  . PHE B 1 607 ? 117.611 92.396  134.186 1.00 25.53  ? 607  PHE B CG  1 
ATOM   8648  C CD1 . PHE B 1 607 ? 118.586 92.612  133.240 1.00 25.53  ? 607  PHE B CD1 1 
ATOM   8649  C CD2 . PHE B 1 607 ? 117.954 92.328  135.512 1.00 25.53  ? 607  PHE B CD2 1 
ATOM   8650  C CE1 . PHE B 1 607 ? 119.881 92.727  133.613 1.00 25.53  ? 607  PHE B CE1 1 
ATOM   8651  C CE2 . PHE B 1 607 ? 119.240 92.448  135.891 1.00 25.53  ? 607  PHE B CE2 1 
ATOM   8652  C CZ  . PHE B 1 607 ? 120.205 92.638  134.943 1.00 25.53  ? 607  PHE B CZ  1 
ATOM   8653  N N   . LEU B 1 608 ? 113.552 94.523  132.684 1.00 23.02  ? 608  LEU B N   1 
ATOM   8654  C CA  . LEU B 1 608 ? 112.479 94.659  131.729 1.00 23.02  ? 608  LEU B CA  1 
ATOM   8655  C C   . LEU B 1 608 ? 112.939 94.987  130.301 1.00 23.02  ? 608  LEU B C   1 
ATOM   8656  O O   . LEU B 1 608 ? 112.240 94.558  129.376 1.00 23.02  ? 608  LEU B O   1 
ATOM   8657  C CB  . LEU B 1 608 ? 111.481 95.684  132.248 1.00 23.02  ? 608  LEU B CB  1 
ATOM   8658  C CG  . LEU B 1 608 ? 110.085 95.635  131.642 1.00 23.02  ? 608  LEU B CG  1 
ATOM   8659  C CD1 . LEU B 1 608 ? 109.494 94.248  131.797 1.00 23.02  ? 608  LEU B CD1 1 
ATOM   8660  C CD2 . LEU B 1 608 ? 109.212 96.650  132.342 1.00 23.02  ? 608  LEU B CD2 1 
ATOM   8661  N N   . PRO B 1 609 ? 114.025 95.746  130.025 1.00 26.71  ? 609  PRO B N   1 
ATOM   8662  C CA  . PRO B 1 609 ? 114.398 95.939  128.609 1.00 26.71  ? 609  PRO B CA  1 
ATOM   8663  C C   . PRO B 1 609 ? 114.865 94.684  127.893 1.00 26.71  ? 609  PRO B C   1 
ATOM   8664  O O   . PRO B 1 609 ? 114.717 94.607  126.668 1.00 26.71  ? 609  PRO B O   1 
ATOM   8665  C CB  . PRO B 1 609 ? 115.519 96.977  128.681 1.00 26.71  ? 609  PRO B CB  1 
ATOM   8666  C CG  . PRO B 1 609 ? 115.282 97.678  129.885 1.00 26.71  ? 609  PRO B CG  1 
ATOM   8667  C CD  . PRO B 1 609 ? 114.829 96.678  130.844 1.00 26.71  ? 609  PRO B CD  1 
ATOM   8668  N N   . TYR B 1 610 ? 115.415 93.704  128.605 1.00 35.55  ? 610  TYR B N   1 
ATOM   8669  C CA  . TYR B 1 610 ? 115.780 92.427  128.016 1.00 35.55  ? 610  TYR B CA  1 
ATOM   8670  C C   . TYR B 1 610 ? 114.603 91.487  127.915 1.00 35.55  ? 610  TYR B C   1 
ATOM   8671  O O   . TYR B 1 610 ? 114.746 90.407  127.353 1.00 35.55  ? 610  TYR B O   1 
ATOM   8672  C CB  . TYR B 1 610 ? 116.878 91.744  128.819 1.00 35.55  ? 610  TYR B CB  1 
ATOM   8673  C CG  . TYR B 1 610 ? 118.246 92.350  128.706 1.00 35.55  ? 610  TYR B CG  1 
ATOM   8674  C CD1 . TYR B 1 610 ? 118.555 93.534  129.336 1.00 35.55  ? 610  TYR B CD1 1 
ATOM   8675  C CD2 . TYR B 1 610 ? 119.238 91.712  128.013 1.00 35.55  ? 610  TYR B CD2 1 
ATOM   8676  C CE1 . TYR B 1 610 ? 119.798 94.078  129.253 1.00 35.55  ? 610  TYR B CE1 1 
ATOM   8677  C CE2 . TYR B 1 610 ? 120.491 92.250  127.928 1.00 35.55  ? 610  TYR B CE2 1 
ATOM   8678  C CZ  . TYR B 1 610 ? 120.763 93.433  128.553 1.00 35.55  ? 610  TYR B CZ  1 
ATOM   8679  O OH  . TYR B 1 610 ? 122.015 93.984  128.472 1.00 35.55  ? 610  TYR B OH  1 
ATOM   8680  N N   . TYR B 1 611 ? 113.460 91.845  128.466 1.00 25.28  ? 611  TYR B N   1 
ATOM   8681  C CA  . TYR B 1 611 ? 112.235 91.125  128.177 1.00 25.28  ? 611  TYR B CA  1 
ATOM   8682  C C   . TYR B 1 611 ? 111.549 91.629  126.931 1.00 25.28  ? 611  TYR B C   1 
ATOM   8683  O O   . TYR B 1 611 ? 110.921 90.837  126.230 1.00 25.28  ? 611  TYR B O   1 
ATOM   8684  C CB  . TYR B 1 611 ? 111.248 91.210  129.352 1.00 25.28  ? 611  TYR B CB  1 
ATOM   8685  C CG  . TYR B 1 611 ? 109.855 90.682  129.050 1.00 25.28  ? 611  TYR B CG  1 
ATOM   8686  C CD1 . TYR B 1 611 ? 108.799 91.545  128.777 1.00 25.28  ? 611  TYR B CD1 1 
ATOM   8687  C CD2 . TYR B 1 611 ? 109.598 89.323  129.032 1.00 25.28  ? 611  TYR B CD2 1 
ATOM   8688  C CE1 . TYR B 1 611 ? 107.539 91.066  128.496 1.00 25.28  ? 611  TYR B CE1 1 
ATOM   8689  C CE2 . TYR B 1 611 ? 108.334 88.841  128.760 1.00 25.28  ? 611  TYR B CE2 1 
ATOM   8690  C CZ  . TYR B 1 611 ? 107.315 89.719  128.487 1.00 25.28  ? 611  TYR B CZ  1 
ATOM   8691  O OH  . TYR B 1 611 ? 106.060 89.245  128.214 1.00 25.28  ? 611  TYR B OH  1 
ATOM   8692  N N   . TRP B 1 612 ? 111.640 92.922  126.638 1.00 21.74  ? 612  TRP B N   1 
ATOM   8693  C CA  . TRP B 1 612 ? 110.994 93.441  125.443 1.00 21.74  ? 612  TRP B CA  1 
ATOM   8694  C C   . TRP B 1 612 ? 111.690 92.975  124.175 1.00 21.74  ? 612  TRP B C   1 
ATOM   8695  O O   . TRP B 1 612 ? 111.033 92.788  123.146 1.00 21.74  ? 612  TRP B O   1 
ATOM   8696  C CB  . TRP B 1 612 ? 110.959 94.962  125.485 1.00 21.74  ? 612  TRP B CB  1 
ATOM   8697  C CG  . TRP B 1 612 ? 110.290 95.543  126.684 1.00 21.74  ? 612  TRP B CG  1 
ATOM   8698  C CD1 . TRP B 1 612 ? 109.303 94.981  127.428 1.00 21.74  ? 612  TRP B CD1 1 
ATOM   8699  C CD2 . TRP B 1 612 ? 110.545 96.827  127.256 1.00 21.74  ? 612  TRP B CD2 1 
ATOM   8700  N NE1 . TRP B 1 612 ? 108.937 95.833  128.439 1.00 21.74  ? 612  TRP B NE1 1 
ATOM   8701  C CE2 . TRP B 1 612 ? 109.689 96.974  128.352 1.00 21.74  ? 612  TRP B CE2 1 
ATOM   8702  C CE3 . TRP B 1 612 ? 111.425 97.865  126.948 1.00 21.74  ? 612  TRP B CE3 1 
ATOM   8703  C CZ2 . TRP B 1 612 ? 109.679 98.117  129.133 1.00 21.74  ? 612  TRP B CZ2 1 
ATOM   8704  C CZ3 . TRP B 1 612 ? 111.416 98.992  127.728 1.00 21.74  ? 612  TRP B CZ3 1 
ATOM   8705  C CH2 . TRP B 1 612 ? 110.555 99.107  128.811 1.00 21.74  ? 612  TRP B CH2 1 
ATOM   8706  N N   . ARG B 1 613 ? 113.002 92.772  124.233 1.00 21.53  ? 613  ARG B N   1 
ATOM   8707  C CA  . ARG B 1 613 ? 113.748 92.251  123.100 1.00 21.53  ? 613  ARG B CA  1 
ATOM   8708  C C   . ARG B 1 613 ? 113.370 90.804  122.840 1.00 21.53  ? 613  ARG B C   1 
ATOM   8709  O O   . ARG B 1 613 ? 113.048 90.430  121.710 1.00 21.53  ? 613  ARG B O   1 
ATOM   8710  C CB  . ARG B 1 613 ? 115.248 92.361  123.349 1.00 21.53  ? 613  ARG B CB  1 
ATOM   8711  C CG  . ARG B 1 613 ? 115.850 93.690  123.003 1.00 21.53  ? 613  ARG B CG  1 
ATOM   8712  C CD  . ARG B 1 613 ? 115.414 94.175  121.635 1.00 21.53  ? 613  ARG B CD  1 
ATOM   8713  N NE  . ARG B 1 613 ? 115.863 93.303  120.562 1.00 21.53  ? 613  ARG B NE  1 
ATOM   8714  C CZ  . ARG B 1 613 ? 115.084 92.902  119.570 1.00 21.53  ? 613  ARG B CZ  1 
ATOM   8715  N NH1 . ARG B 1 613 ? 113.833 93.306  119.522 1.00 21.53  ? 613  ARG B NH1 1 
ATOM   8716  N NH2 . ARG B 1 613 ? 115.552 92.105  118.631 1.00 21.53  ? 613  ARG B NH2 1 
ATOM   8717  N N   . ALA B 1 614 ? 113.384 89.990  123.888 1.00 20.27  ? 614  ALA B N   1 
ATOM   8718  C CA  . ALA B 1 614 ? 113.132 88.564  123.763 1.00 20.27  ? 614  ALA B CA  1 
ATOM   8719  C C   . ALA B 1 614 ? 111.687 88.250  123.404 1.00 20.27  ? 614  ALA B C   1 
ATOM   8720  O O   . ALA B 1 614 ? 111.381 87.118  123.034 1.00 20.27  ? 614  ALA B O   1 
ATOM   8721  C CB  . ALA B 1 614 ? 113.515 87.844  125.054 1.00 20.27  ? 614  ALA B CB  1 
ATOM   8722  N N   . MET B 1 615 ? 110.785 89.213  123.519 1.00 31.21  ? 615  MET B N   1 
ATOM   8723  C CA  . MET B 1 615 ? 109.433 88.996  123.031 1.00 31.21  ? 615  MET B CA  1 
ATOM   8724  C C   . MET B 1 615 ? 109.131 89.752  121.752 1.00 31.21  ? 615  MET B C   1 
ATOM   8725  O O   . MET B 1 615 ? 107.973 89.782  121.335 1.00 31.21  ? 615  MET B O   1 
ATOM   8726  C CB  . MET B 1 615 ? 108.419 89.354  124.106 1.00 31.21  ? 615  MET B CB  1 
ATOM   8727  C CG  . MET B 1 615 ? 108.406 88.354  125.231 1.00 31.21  ? 615  MET B CG  1 
ATOM   8728  S SD  . MET B 1 615 ? 107.166 87.065  125.005 1.00 31.21  ? 615  MET B SD  1 
ATOM   8729  C CE  . MET B 1 615 ? 107.842 85.754  126.021 1.00 31.21  ? 615  MET B CE  1 
ATOM   8730  N N   . GLN B 1 616 ? 110.135 90.363  121.126 1.00 26.16  ? 616  GLN B N   1 
ATOM   8731  C CA  . GLN B 1 616 ? 109.999 90.837  119.755 1.00 26.16  ? 616  GLN B CA  1 
ATOM   8732  C C   . GLN B 1 616 ? 110.558 89.838  118.760 1.00 26.16  ? 616  GLN B C   1 
ATOM   8733  O O   . GLN B 1 616 ? 110.077 89.777  117.625 1.00 26.16  ? 616  GLN B O   1 
ATOM   8734  C CB  . GLN B 1 616 ? 110.719 92.169  119.570 1.00 26.16  ? 616  GLN B CB  1 
ATOM   8735  C CG  . GLN B 1 616 ? 109.959 93.390  120.014 1.00 26.16  ? 616  GLN B CG  1 
ATOM   8736  C CD  . GLN B 1 616 ? 110.857 94.590  120.101 1.00 26.16  ? 616  GLN B CD  1 
ATOM   8737  O OE1 . GLN B 1 616 ? 111.831 94.690  119.370 1.00 26.16  ? 616  GLN B OE1 1 
ATOM   8738  N NE2 . GLN B 1 616 ? 110.545 95.504  121.001 1.00 26.16  ? 616  GLN B NE2 1 
ATOM   8739  N N   . CYS B 1 617 ? 111.573 89.073  119.160 1.00 26.94  ? 617  CYS B N   1 
ATOM   8740  C CA  . CYS B 1 617 ? 112.071 87.943  118.395 1.00 26.94  ? 617  CYS B CA  1 
ATOM   8741  C C   . CYS B 1 617 ? 111.093 86.783  118.382 1.00 26.94  ? 617  CYS B C   1 
ATOM   8742  O O   . CYS B 1 617 ? 111.124 85.975  117.453 1.00 26.94  ? 617  CYS B O   1 
ATOM   8743  C CB  . CYS B 1 617 ? 113.409 87.476  118.962 1.00 26.94  ? 617  CYS B CB  1 
ATOM   8744  S SG  . CYS B 1 617 ? 114.567 88.808  119.240 1.00 26.94  ? 617  CYS B SG  1 
ATOM   8745  N N   . ALA B 1 618 ? 110.230 86.684  119.390 1.00 32.58  ? 618  ALA B N   1 
ATOM   8746  C CA  . ALA B 1 618 ? 109.183 85.674  119.374 1.00 32.58  ? 618  ALA B CA  1 
ATOM   8747  C C   . ALA B 1 618 ? 108.122 86.011  118.340 1.00 32.58  ? 618  ALA B C   1 
ATOM   8748  O O   . ALA B 1 618 ? 107.652 85.124  117.624 1.00 32.58  ? 618  ALA B O   1 
ATOM   8749  C CB  . ALA B 1 618 ? 108.557 85.534  120.760 1.00 32.58  ? 618  ALA B CB  1 
ATOM   8750  N N   . ARG B 1 619 ? 107.731 87.277  118.243 1.00 41.54  ? 619  ARG B N   1 
ATOM   8751  C CA  . ARG B 1 619 ? 106.892 87.583  117.091 1.00 41.54  ? 619  ARG B CA  1 
ATOM   8752  C C   . ARG B 1 619 ? 107.699 87.585  115.784 1.00 41.54  ? 619  ARG B C   1 
ATOM   8753  O O   . ARG B 1 619 ? 107.189 87.289  114.693 1.00 41.54  ? 619  ARG B O   1 
ATOM   8754  C CB  . ARG B 1 619 ? 106.156 88.913  117.282 1.00 41.54  ? 619  ARG B CB  1 
ATOM   8755  C CG  . ARG B 1 619 ? 105.128 89.192  116.189 1.00 41.54  ? 619  ARG B CG  1 
ATOM   8756  C CD  . ARG B 1 619 ? 104.050 90.165  116.572 1.00 41.54  ? 619  ARG B CD  1 
ATOM   8757  N NE  . ARG B 1 619 ? 103.411 90.696  115.374 1.00 41.54  ? 619  ARG B NE  1 
ATOM   8758  C CZ  . ARG B 1 619 ? 102.218 91.278  115.348 1.00 41.54  ? 619  ARG B CZ  1 
ATOM   8759  N NH1 . ARG B 1 619 ? 101.508 91.392  116.459 1.00 41.54  ? 619  ARG B NH1 1 
ATOM   8760  N NH2 . ARG B 1 619 ? 101.729 91.732  114.204 1.00 41.54  ? 619  ARG B NH2 1 
ATOM   8761  N N   . ARG B 1 620 ? 109.010 87.811  115.815 1.00 36.12  ? 620  ARG B N   1 
ATOM   8762  C CA  . ARG B 1 620 ? 109.839 87.632  114.630 1.00 36.12  ? 620  ARG B CA  1 
ATOM   8763  C C   . ARG B 1 620 ? 110.194 86.169  114.380 1.00 36.12  ? 620  ARG B C   1 
ATOM   8764  O O   . ARG B 1 620 ? 111.013 85.887  113.502 1.00 36.12  ? 620  ARG B O   1 
ATOM   8765  C CB  . ARG B 1 620 ? 111.109 88.481  114.728 1.00 36.12  ? 620  ARG B CB  1 
ATOM   8766  C CG  . ARG B 1 620 ? 111.382 89.302  113.481 1.00 36.12  ? 620  ARG B CG  1 
ATOM   8767  C CD  . ARG B 1 620 ? 112.405 90.383  113.730 1.00 36.12  ? 620  ARG B CD  1 
ATOM   8768  N NE  . ARG B 1 620 ? 113.725 89.843  114.033 1.00 36.12  ? 620  ARG B NE  1 
ATOM   8769  C CZ  . ARG B 1 620 ? 114.809 90.588  114.222 1.00 36.12  ? 620  ARG B CZ  1 
ATOM   8770  N NH1 . ARG B 1 620 ? 114.734 91.906  114.140 1.00 36.12  ? 620  ARG B NH1 1 
ATOM   8771  N NH2 . ARG B 1 620 ? 115.971 90.018  114.492 1.00 36.12  ? 620  ARG B NH2 1 
ATOM   8772  N N   . TRP B 1 621 ? 109.575 85.232  115.102 1.00 45.83  ? 621  TRP B N   1 
ATOM   8773  C CA  . TRP B 1 621 ? 109.714 83.804  114.845 1.00 45.83  ? 621  TRP B CA  1 
ATOM   8774  C C   . TRP B 1 621 ? 108.415 83.158  114.390 1.00 45.83  ? 621  TRP B C   1 
ATOM   8775  O O   . TRP B 1 621 ? 108.429 82.401  113.414 1.00 45.83  ? 621  TRP B O   1 
ATOM   8776  C CB  . TRP B 1 621 ? 110.248 83.083  116.086 1.00 45.83  ? 621  TRP B CB  1 
ATOM   8777  C CG  . TRP B 1 621 ? 109.904 81.637  116.126 1.00 45.83  ? 621  TRP B CG  1 
ATOM   8778  C CD1 . TRP B 1 621 ? 110.416 80.650  115.338 1.00 45.83  ? 621  TRP B CD1 1 
ATOM   8779  C CD2 . TRP B 1 621 ? 108.978 81.004  117.012 1.00 45.83  ? 621  TRP B CD2 1 
ATOM   8780  N NE1 . TRP B 1 621 ? 109.862 79.439  115.675 1.00 45.83  ? 621  TRP B NE1 1 
ATOM   8781  C CE2 . TRP B 1 621 ? 108.975 79.631  116.701 1.00 45.83  ? 621  TRP B CE2 1 
ATOM   8782  C CE3 . TRP B 1 621 ? 108.146 81.466  118.037 1.00 45.83  ? 621  TRP B CE3 1 
ATOM   8783  C CZ2 . TRP B 1 621 ? 108.174 78.717  117.376 1.00 45.83  ? 621  TRP B CZ2 1 
ATOM   8784  C CZ3 . TRP B 1 621 ? 107.354 80.560  118.706 1.00 45.83  ? 621  TRP B CZ3 1 
ATOM   8785  C CH2 . TRP B 1 621 ? 107.372 79.200  118.374 1.00 45.83  ? 621  TRP B CH2 1 
ATOM   8786  N N   . PHE B 1 622 ? 107.380 83.375  115.195 1.00 44.46  ? 622  PHE B N   1 
ATOM   8787  C CA  . PHE B 1 622 ? 106.039 82.903  114.804 1.00 44.46  ? 622  PHE B CA  1 
ATOM   8788  C C   . PHE B 1 622 ? 105.638 83.843  113.688 1.00 44.46  ? 622  PHE B C   1 
ATOM   8789  O O   . PHE B 1 622 ? 104.453 83.924  113.359 1.00 44.46  ? 622  PHE B O   1 
ATOM   8790  C CB  . PHE B 1 622 ? 105.107 82.816  116.017 1.00 44.46  ? 622  PHE B CB  1 
ATOM   8791  C CG  . PHE B 1 622 ? 103.662 82.419  115.837 1.00 44.46  ? 622  PHE B CG  1 
ATOM   8792  C CD1 . PHE B 1 622 ? 103.327 81.082  115.694 1.00 44.46  ? 622  PHE B CD1 1 
ATOM   8793  C CD2 . PHE B 1 622 ? 102.654 83.360  115.711 1.00 44.46  ? 622  PHE B CD2 1 
ATOM   8794  C CE1 . PHE B 1 622 ? 102.014 80.695  115.482 1.00 44.46  ? 622  PHE B CE1 1 
ATOM   8795  C CE2 . PHE B 1 622 ? 101.340 82.972  115.502 1.00 44.46  ? 622  PHE B CE2 1 
ATOM   8796  C CZ  . PHE B 1 622 ? 101.022 81.640  115.388 1.00 44.46  ? 622  PHE B CZ  1 
ATOM   8797  N N   . ASP B 1 623 ? 106.625 84.557  113.162 1.00 56.42  ? 623  ASP B N   1 
ATOM   8798  C CA  . ASP B 1 623 ? 106.375 85.411  111.973 1.00 56.42  ? 623  ASP B CA  1 
ATOM   8799  C C   . ASP B 1 623 ? 107.695 85.477  111.210 1.00 56.42  ? 623  ASP B C   1 
ATOM   8800  O O   . ASP B 1 623 ? 108.712 85.799  111.857 1.00 56.42  ? 623  ASP B O   1 
ATOM   8801  C CB  . ASP B 1 623 ? 105.772 86.766  112.336 1.00 56.42  ? 623  ASP B CB  1 
ATOM   8802  C CG  . ASP B 1 623 ? 105.423 87.609  111.124 1.00 56.42  ? 623  ASP B CG  1 
ATOM   8803  O OD1 . ASP B 1 623 ? 105.635 87.124  109.994 1.00 56.42  ? 623  ASP B OD1 1 
ATOM   8804  O OD2 . ASP B 1 623 ? 104.946 88.745  111.320 1.00 56.42  ? 623  ASP B OD2 1 
ATOM   8805  N N   . GLU B 1 624 ? 107.666 85.186  109.907 1.00 58.89  ? 624  GLU B N   1 
ATOM   8806  C CA  . GLU B 1 624 ? 108.894 85.088  109.105 1.00 58.89  ? 624  GLU B CA  1 
ATOM   8807  C C   . GLU B 1 624 ? 109.633 83.762  109.322 1.00 58.89  ? 624  GLU B C   1 
ATOM   8808  O O   . GLU B 1 624 ? 110.520 83.403  108.541 1.00 58.89  ? 624  GLU B O   1 
ATOM   8809  C CB  . GLU B 1 624 ? 109.815 86.298  109.371 1.00 58.89  ? 624  GLU B CB  1 
ATOM   8810  C CG  . GLU B 1 624 ? 110.915 86.575  108.367 1.00 58.89  ? 624  GLU B CG  1 
ATOM   8811  C CD  . GLU B 1 624 ? 111.894 87.602  108.882 1.00 58.89  ? 624  GLU B CD  1 
ATOM   8812  O OE1 . GLU B 1 624 ? 113.094 87.280  108.984 1.00 58.89  ? 624  GLU B OE1 1 
ATOM   8813  O OE2 . GLU B 1 624 ? 111.463 88.731  109.193 1.00 58.89  ? 624  GLU B OE2 1 
ATOM   8814  N N   . GLY B 1 625 ? 109.248 82.996  110.339 1.00 54.70  ? 625  GLY B N   1 
ATOM   8815  C CA  . GLY B 1 625 ? 109.550 81.580  110.398 1.00 54.70  ? 625  GLY B CA  1 
ATOM   8816  C C   . GLY B 1 625 ? 110.945 81.121  110.775 1.00 54.70  ? 625  GLY B C   1 
ATOM   8817  O O   . GLY B 1 625 ? 111.086 80.049  111.368 1.00 54.70  ? 625  GLY B O   1 
ATOM   8818  N N   . GLU B 1 626 ? 111.975 81.906  110.455 1.00 55.32  ? 626  GLU B N   1 
ATOM   8819  C CA  . GLU B 1 626 ? 113.323 81.358  110.336 1.00 55.32  ? 626  GLU B CA  1 
ATOM   8820  C C   . GLU B 1 626 ? 113.952 81.044  111.689 1.00 55.32  ? 626  GLU B C   1 
ATOM   8821  O O   . GLU B 1 626 ? 113.482 81.499  112.735 1.00 55.32  ? 626  GLU B O   1 
ATOM   8822  C CB  . GLU B 1 626 ? 114.214 82.319  109.552 1.00 55.32  ? 626  GLU B CB  1 
ATOM   8823  C CG  . GLU B 1 626 ? 114.375 83.686  110.170 1.00 55.32  ? 626  GLU B CG  1 
ATOM   8824  C CD  . GLU B 1 626 ? 115.231 84.596  109.318 1.00 55.32  ? 626  GLU B CD  1 
ATOM   8825  O OE1 . GLU B 1 626 ? 115.702 84.140  108.257 1.00 55.32  ? 626  GLU B OE1 1 
ATOM   8826  O OE2 . GLU B 1 626 ? 115.439 85.764  109.704 1.00 55.32  ? 626  GLU B OE2 1 
ATOM   8827  N N   . THR B 1 627 ? 115.015 80.238  111.653 1.00 53.95  ? 627  THR B N   1 
ATOM   8828  C CA  . THR B 1 627 ? 115.703 79.747  112.840 1.00 53.95  ? 627  THR B CA  1 
ATOM   8829  C C   . THR B 1 627 ? 116.528 80.832  113.522 1.00 53.95  ? 627  THR B C   1 
ATOM   8830  O O   . THR B 1 627 ? 116.636 80.823  114.754 1.00 53.95  ? 627  THR B O   1 
ATOM   8831  C CB  . THR B 1 627 ? 116.579 78.550  112.429 1.00 53.95  ? 627  THR B CB  1 
ATOM   8832  O OG1 . THR B 1 627 ? 115.740 77.520  111.895 1.00 53.95  ? 627  THR B OG1 1 
ATOM   8833  C CG2 . THR B 1 627 ? 117.365 77.956  113.600 1.00 53.95  ? 627  THR B CG2 1 
ATOM   8834  N N   . SER B 1 628 ? 117.044 81.805  112.763 1.00 44.80  ? 628  SER B N   1 
ATOM   8835  C CA  . SER B 1 628 ? 117.943 82.806  113.331 1.00 44.80  ? 628  SER B CA  1 
ATOM   8836  C C   . SER B 1 628 ? 117.232 83.751  114.293 1.00 44.80  ? 628  SER B C   1 
ATOM   8837  O O   . SER B 1 628 ? 117.886 84.380  115.130 1.00 44.80  ? 628  SER B O   1 
ATOM   8838  C CB  . SER B 1 628 ? 118.613 83.601  112.217 1.00 44.80  ? 628  SER B CB  1 
ATOM   8839  O OG  . SER B 1 628 ? 119.471 84.589  112.758 1.00 44.80  ? 628  SER B OG  1 
ATOM   8840  N N   . HIS B 1 629 ? 115.911 83.873  114.199 1.00 42.46  ? 629  HIS B N   1 
ATOM   8841  C CA  . HIS B 1 629 ? 115.156 84.545  115.254 1.00 42.46  ? 629  HIS B CA  1 
ATOM   8842  C C   . HIS B 1 629 ? 114.627 83.548  116.276 1.00 42.46  ? 629  HIS B C   1 
ATOM   8843  O O   . HIS B 1 629 ? 113.461 83.565  116.655 1.00 42.46  ? 629  HIS B O   1 
ATOM   8844  C CB  . HIS B 1 629 ? 114.028 85.355  114.640 1.00 42.46  ? 629  HIS B CB  1 
ATOM   8845  C CG  . HIS B 1 629 ? 114.472 86.224  113.511 1.00 42.46  ? 629  HIS B CG  1 
ATOM   8846  N ND1 . HIS B 1 629 ? 115.660 86.922  113.537 1.00 42.46  ? 629  HIS B ND1 1 
ATOM   8847  C CD2 . HIS B 1 629 ? 113.905 86.490  112.313 1.00 42.46  ? 629  HIS B CD2 1 
ATOM   8848  C CE1 . HIS B 1 629 ? 115.800 87.590  112.406 1.00 42.46  ? 629  HIS B CE1 1 
ATOM   8849  N NE2 . HIS B 1 629 ? 114.749 87.344  111.645 1.00 42.46  ? 629  HIS B NE2 1 
ATOM   8850  N N   . LEU B 1 630 ? 115.510 82.656  116.713 1.00 34.52  ? 630  LEU B N   1 
ATOM   8851  C CA  . LEU B 1 630 ? 115.320 81.834  117.898 1.00 34.52  ? 630  LEU B CA  1 
ATOM   8852  C C   . LEU B 1 630 ? 116.589 81.754  118.712 1.00 34.52  ? 630  LEU B C   1 
ATOM   8853  O O   . LEU B 1 630 ? 116.517 81.498  119.915 1.00 34.52  ? 630  LEU B O   1 
ATOM   8854  C CB  . LEU B 1 630 ? 114.878 80.413  117.527 1.00 34.52  ? 630  LEU B CB  1 
ATOM   8855  C CG  . LEU B 1 630 ? 113.418 80.207  117.131 1.00 34.52  ? 630  LEU B CG  1 
ATOM   8856  C CD1 . LEU B 1 630 ? 113.198 78.797  116.622 1.00 34.52  ? 630  LEU B CD1 1 
ATOM   8857  C CD2 . LEU B 1 630 ? 112.506 80.499  118.304 1.00 34.52  ? 630  LEU B CD2 1 
ATOM   8858  N N   . VAL B 1 631 ? 117.747 81.959  118.093 1.00 26.79  ? 631  VAL B N   1 
ATOM   8859  C CA  . VAL B 1 631 ? 118.993 82.140  118.815 1.00 26.79  ? 631  VAL B CA  1 
ATOM   8860  C C   . VAL B 1 631 ? 119.179 83.604  119.198 1.00 26.79  ? 631  VAL B C   1 
ATOM   8861  O O   . VAL B 1 631 ? 119.939 83.906  120.133 1.00 26.79  ? 631  VAL B O   1 
ATOM   8862  C CB  . VAL B 1 631 ? 120.166 81.607  117.966 1.00 26.79  ? 631  VAL B CB  1 
ATOM   8863  C CG1 . VAL B 1 631 ? 121.426 81.410  118.783 1.00 26.79  ? 631  VAL B CG1 1 
ATOM   8864  C CG2 . VAL B 1 631 ? 119.769 80.318  117.297 1.00 26.79  ? 631  VAL B CG2 1 
ATOM   8865  N N   . ASN B 1 632 ? 118.468 84.520  118.536 1.00 23.38  ? 632  ASN B N   1 
ATOM   8866  C CA  . ASN B 1 632 ? 118.356 85.890  119.027 1.00 23.38  ? 632  ASN B CA  1 
ATOM   8867  C C   . ASN B 1 632 ? 117.554 85.932  120.317 1.00 23.38  ? 632  ASN B C   1 
ATOM   8868  O O   . ASN B 1 632 ? 117.914 86.643  121.260 1.00 23.38  ? 632  ASN B O   1 
ATOM   8869  C CB  . ASN B 1 632 ? 117.695 86.769  117.969 1.00 23.38  ? 632  ASN B CB  1 
ATOM   8870  C CG  . ASN B 1 632 ? 118.096 88.214  118.079 1.00 23.38  ? 632  ASN B CG  1 
ATOM   8871  O OD1 . ASN B 1 632 ? 117.850 88.863  119.088 1.00 23.38  ? 632  ASN B OD1 1 
ATOM   8872  N ND2 . ASN B 1 632 ? 118.704 88.735  117.031 1.00 23.38  ? 632  ASN B ND2 1 
ATOM   8873  N N   . LEU B 1 633 ? 116.456 85.170  120.366 1.00 21.37  ? 633  LEU B N   1 
ATOM   8874  C CA  . LEU B 1 633 ? 115.609 85.080  121.553 1.00 21.37  ? 633  LEU B CA  1 
ATOM   8875  C C   . LEU B 1 633 ? 116.370 84.495  122.728 1.00 21.37  ? 633  LEU B C   1 
ATOM   8876  O O   . LEU B 1 633 ? 116.116 84.839  123.883 1.00 21.37  ? 633  LEU B O   1 
ATOM   8877  C CB  . LEU B 1 633 ? 114.374 84.227  121.248 1.00 21.37  ? 633  LEU B CB  1 
ATOM   8878  C CG  . LEU B 1 633 ? 113.301 84.013  122.316 1.00 21.37  ? 633  LEU B CG  1 
ATOM   8879  C CD1 . LEU B 1 633 ? 111.930 84.137  121.690 1.00 21.37  ? 633  LEU B CD1 1 
ATOM   8880  C CD2 . LEU B 1 633 ? 113.435 82.657  122.981 1.00 21.37  ? 633  LEU B CD2 1 
ATOM   8881  N N   . GLY B 1 634 ? 117.297 83.593  122.446 1.00 19.01  ? 634  GLY B N   1 
ATOM   8882  C CA  . GLY B 1 634 ? 118.101 82.996  123.482 1.00 19.01  ? 634  GLY B CA  1 
ATOM   8883  C C   . GLY B 1 634 ? 119.061 83.976  124.114 1.00 19.01  ? 634  GLY B C   1 
ATOM   8884  O O   . GLY B 1 634 ? 119.482 83.770  125.256 1.00 19.01  ? 634  GLY B O   1 
ATOM   8885  N N   . LYS B 1 635 ? 119.412 85.045  123.388 1.00 15.06  ? 635  LYS B N   1 
ATOM   8886  C CA  . LYS B 1 635 ? 120.487 85.933  123.825 1.00 15.06  ? 635  LYS B CA  1 
ATOM   8887  C C   . LYS B 1 635 ? 120.081 86.796  125.011 1.00 15.06  ? 635  LYS B C   1 
ATOM   8888  O O   . LYS B 1 635 ? 120.926 87.143  125.846 1.00 15.06  ? 635  LYS B O   1 
ATOM   8889  C CB  . LYS B 1 635 ? 120.941 86.802  122.658 1.00 15.06  ? 635  LYS B CB  1 
ATOM   8890  C CG  . LYS B 1 635 ? 122.186 87.615  122.913 1.00 15.06  ? 635  LYS B CG  1 
ATOM   8891  C CD  . LYS B 1 635 ? 122.522 88.446  121.707 1.00 15.06  ? 635  LYS B CD  1 
ATOM   8892  C CE  . LYS B 1 635 ? 121.964 89.843  121.795 1.00 15.06  ? 635  LYS B CE  1 
ATOM   8893  N NZ  . LYS B 1 635 ? 122.807 90.794  121.025 1.00 15.06  ? 635  LYS B NZ  1 
ATOM   8894  N N   . TYR B 1 636 ? 118.802 87.145  125.110 1.00 18.93  ? 636  TYR B N   1 
ATOM   8895  C CA  . TYR B 1 636 ? 118.320 87.978  126.197 1.00 18.93  ? 636  TYR B CA  1 
ATOM   8896  C C   . TYR B 1 636 ? 117.830 87.152  127.378 1.00 18.93  ? 636  TYR B C   1 
ATOM   8897  O O   . TYR B 1 636 ? 117.869 87.610  128.521 1.00 18.93  ? 636  TYR B O   1 
ATOM   8898  C CB  . TYR B 1 636 ? 117.218 88.892  125.673 1.00 18.93  ? 636  TYR B CB  1 
ATOM   8899  C CG  . TYR B 1 636 ? 117.641 89.630  124.433 1.00 18.93  ? 636  TYR B CG  1 
ATOM   8900  C CD1 . TYR B 1 636 ? 118.561 90.662  124.496 1.00 18.93  ? 636  TYR B CD1 1 
ATOM   8901  C CD2 . TYR B 1 636 ? 117.154 89.269  123.199 1.00 18.93  ? 636  TYR B CD2 1 
ATOM   8902  C CE1 . TYR B 1 636 ? 118.958 91.322  123.370 1.00 18.93  ? 636  TYR B CE1 1 
ATOM   8903  C CE2 . TYR B 1 636 ? 117.557 89.918  122.070 1.00 18.93  ? 636  TYR B CE2 1 
ATOM   8904  C CZ  . TYR B 1 636 ? 118.455 90.942  122.161 1.00 18.93  ? 636  TYR B CZ  1 
ATOM   8905  O OH  . TYR B 1 636 ? 118.846 91.588  121.019 1.00 18.93  ? 636  TYR B OH  1 
ATOM   8906  N N   . VAL B 1 637 ? 117.390 85.924  127.122 1.00 12.28  ? 637  VAL B N   1 
ATOM   8907  C CA  . VAL B 1 637 ? 117.053 84.967  128.168 1.00 12.28  ? 637  VAL B CA  1 
ATOM   8908  C C   . VAL B 1 637 ? 118.354 84.551  128.838 1.00 12.28  ? 637  VAL B C   1 
ATOM   8909  O O   . VAL B 1 637 ? 118.379 84.255  130.036 1.00 12.28  ? 637  VAL B O   1 
ATOM   8910  C CB  . VAL B 1 637 ? 116.276 83.770  127.588 1.00 12.28  ? 637  VAL B CB  1 
ATOM   8911  C CG1 . VAL B 1 637 ? 115.945 82.745  128.637 1.00 12.28  ? 637  VAL B CG1 1 
ATOM   8912  C CG2 . VAL B 1 637 ? 114.993 84.256  126.960 1.00 12.28  ? 637  VAL B CG2 1 
ATOM   8913  N N   . SER B 1 638 ? 119.452 84.575  128.087 1.00 14.39  ? 638  SER B N   1 
ATOM   8914  C CA  . SER B 1 638 ? 120.768 84.348  128.665 1.00 14.39  ? 638  SER B CA  1 
ATOM   8915  C C   . SER B 1 638 ? 121.162 85.387  129.702 1.00 14.39  ? 638  SER B C   1 
ATOM   8916  O O   . SER B 1 638 ? 121.616 85.015  130.787 1.00 14.39  ? 638  SER B O   1 
ATOM   8917  C CB  . SER B 1 638 ? 121.832 84.329  127.583 1.00 14.39  ? 638  SER B CB  1 
ATOM   8918  O OG  . SER B 1 638 ? 123.098 84.170  128.177 1.00 14.39  ? 638  SER B OG  1 
ATOM   8919  N N   . ALA B 1 639 ? 121.013 86.676  129.409 1.00 19.36  ? 639  ALA B N   1 
ATOM   8920  C CA  . ALA B 1 639 ? 121.238 87.704  130.429 1.00 19.36  ? 639  ALA B CA  1 
ATOM   8921  C C   . ALA B 1 639 ? 119.945 88.103  131.131 1.00 19.36  ? 639  ALA B C   1 
ATOM   8922  O O   . ALA B 1 639 ? 119.630 89.273  131.301 1.00 19.36  ? 639  ALA B O   1 
ATOM   8923  C CB  . ALA B 1 639 ? 121.911 88.916  129.807 1.00 19.36  ? 639  ALA B CB  1 
ATOM   8924  N N   . MET B 1 640 ? 119.209 87.120  131.546 1.00 18.58  ? 640  MET B N   1 
ATOM   8925  C CA  . MET B 1 640 ? 118.091 87.183  132.470 1.00 18.58  ? 640  MET B CA  1 
ATOM   8926  C C   . MET B 1 640 ? 118.181 86.061  133.481 1.00 18.58  ? 640  MET B C   1 
ATOM   8927  O O   . MET B 1 640 ? 117.604 86.158  134.563 1.00 18.58  ? 640  MET B O   1 
ATOM   8928  C CB  . MET B 1 640 ? 116.755 87.116  131.728 1.00 18.58  ? 640  MET B CB  1 
ATOM   8929  C CG  . MET B 1 640 ? 116.253 88.450  131.247 1.00 18.58  ? 640  MET B CG  1 
ATOM   8930  S SD  . MET B 1 640 ? 114.466 88.615  131.356 1.00 18.58  ? 640  MET B SD  1 
ATOM   8931  C CE  . MET B 1 640 ? 113.946 87.872  129.822 1.00 18.58  ? 640  MET B CE  1 
ATOM   8932  N N   . LEU B 1 641 ? 118.891 84.993  133.144 1.00 24.22  ? 641  LEU B N   1 
ATOM   8933  C CA  . LEU B 1 641 ? 119.289 83.975  134.093 1.00 24.22  ? 641  LEU B CA  1 
ATOM   8934  C C   . LEU B 1 641 ? 120.595 84.319  134.776 1.00 24.22  ? 641  LEU B C   1 
ATOM   8935  O O   . LEU B 1 641 ? 120.748 84.032  135.965 1.00 24.22  ? 641  LEU B O   1 
ATOM   8936  C CB  . LEU B 1 641 ? 119.420 82.626  133.394 1.00 24.22  ? 641  LEU B CB  1 
ATOM   8937  C CG  . LEU B 1 641 ? 118.203 82.114  132.635 1.00 24.22  ? 641  LEU B CG  1 
ATOM   8938  C CD1 . LEU B 1 641 ? 118.440 80.689  132.204 1.00 24.22  ? 641  LEU B CD1 1 
ATOM   8939  C CD2 . LEU B 1 641 ? 116.954 82.213  133.484 1.00 24.22  ? 641  LEU B CD2 1 
ATOM   8940  N N   . ALA B 1 642 ? 121.529 84.949  134.060 1.00 28.07  ? 642  ALA B N   1 
ATOM   8941  C CA  . ALA B 1 642 ? 122.830 85.283  134.618 1.00 28.07  ? 642  ALA B CA  1 
ATOM   8942  C C   . ALA B 1 642 ? 122.771 86.338  135.708 1.00 28.07  ? 642  ALA B C   1 
ATOM   8943  O O   . ALA B 1 642 ? 123.643 86.351  136.580 1.00 28.07  ? 642  ALA B O   1 
ATOM   8944  C CB  . ALA B 1 642 ? 123.777 85.765  133.514 1.00 28.07  ? 642  ALA B CB  1 
ATOM   8945  N N   . ALA B 1 643 ? 121.773 87.214  135.683 1.00 32.55  ? 643  ALA B N   1 
ATOM   8946  C CA  . ALA B 1 643 ? 121.479 88.057  136.826 1.00 32.55  ? 643  ALA B CA  1 
ATOM   8947  C C   . ALA B 1 643 ? 120.393 87.475  137.710 1.00 32.55  ? 643  ALA B C   1 
ATOM   8948  O O   . ALA B 1 643 ? 120.260 87.896  138.862 1.00 32.55  ? 643  ALA B O   1 
ATOM   8949  C CB  . ALA B 1 643 ? 121.065 89.449  136.366 1.00 32.55  ? 643  ALA B CB  1 
ATOM   8950  N N   . GLY B 1 644 ? 119.627 86.509  137.202 1.00 35.04  ? 644  GLY B N   1 
ATOM   8951  C CA  . GLY B 1 644 ? 118.707 85.766  138.041 1.00 35.04  ? 644  GLY B CA  1 
ATOM   8952  C C   . GLY B 1 644 ? 119.387 84.849  139.035 1.00 35.04  ? 644  GLY B C   1 
ATOM   8953  O O   . GLY B 1 644 ? 118.748 84.416  139.997 1.00 35.04  ? 644  GLY B O   1 
ATOM   8954  N N   . THR B 1 645 ? 120.667 84.535  138.820 1.00 38.57  ? 645  THR B N   1 
ATOM   8955  C CA  . THR B 1 645 ? 121.435 83.821  139.829 1.00 38.57  ? 645  THR B CA  1 
ATOM   8956  C C   . THR B 1 645 ? 121.919 84.751  140.936 1.00 38.57  ? 645  THR B C   1 
ATOM   8957  O O   . THR B 1 645 ? 122.162 84.294  142.058 1.00 38.57  ? 645  THR B O   1 
ATOM   8958  C CB  . THR B 1 645 ? 122.625 83.105  139.189 1.00 38.57  ? 645  THR B CB  1 
ATOM   8959  O OG1 . THR B 1 645 ? 123.429 84.053  138.482 1.00 38.57  ? 645  THR B OG1 1 
ATOM   8960  C CG2 . THR B 1 645 ? 122.153 82.034  138.229 1.00 38.57  ? 645  THR B CG2 1 
ATOM   8961  N N   . LYS B 1 646 ? 122.062 86.049  140.653 1.00 40.18  ? 646  LYS B N   1 
ATOM   8962  C CA  . LYS B 1 646 ? 122.397 86.999  141.710 1.00 40.18  ? 646  LYS B CA  1 
ATOM   8963  C C   . LYS B 1 646 ? 121.222 87.230  142.646 1.00 40.18  ? 646  LYS B C   1 
ATOM   8964  O O   . LYS B 1 646 ? 121.430 87.614  143.801 1.00 40.18  ? 646  LYS B O   1 
ATOM   8965  C CB  . LYS B 1 646 ? 122.865 88.324  141.106 1.00 40.18  ? 646  LYS B CB  1 
ATOM   8966  C CG  . LYS B 1 646 ? 123.560 89.273  142.080 1.00 40.18  ? 646  LYS B CG  1 
ATOM   8967  C CD  . LYS B 1 646 ? 124.940 88.779  142.458 1.00 40.18  ? 646  LYS B CD  1 
ATOM   8968  C CE  . LYS B 1 646 ? 125.952 89.118  141.388 1.00 40.18  ? 646  LYS B CE  1 
ATOM   8969  N NZ  . LYS B 1 646 ? 127.153 88.248  141.439 1.00 40.18  ? 646  LYS B NZ  1 
ATOM   8970  N N   . VAL B 1 647 ? 119.998 86.995  142.169 1.00 41.85  ? 647  VAL B N   1 
ATOM   8971  C CA  . VAL B 1 647 ? 118.830 86.995  143.044 1.00 41.85  ? 647  VAL B CA  1 
ATOM   8972  C C   . VAL B 1 647 ? 118.962 85.904  144.101 1.00 41.85  ? 647  VAL B C   1 
ATOM   8973  O O   . VAL B 1 647 ? 118.638 86.112  145.277 1.00 41.85  ? 647  VAL B O   1 
ATOM   8974  C CB  . VAL B 1 647 ? 117.550 86.843  142.199 1.00 41.85  ? 647  VAL B CB  1 
ATOM   8975  C CG1 . VAL B 1 647 ? 116.335 86.512  143.053 1.00 41.85  ? 647  VAL B CG1 1 
ATOM   8976  C CG2 . VAL B 1 647 ? 117.295 88.114  141.411 1.00 41.85  ? 647  VAL B CG2 1 
ATOM   8977  N N   . ALA B 1 648 ? 119.499 84.751  143.718 1.00 48.16  ? 648  ALA B N   1 
ATOM   8978  C CA  . ALA B 1 648 ? 119.778 83.680  144.660 1.00 48.16  ? 648  ALA B CA  1 
ATOM   8979  C C   . ALA B 1 648 ? 121.242 83.622  145.075 1.00 48.16  ? 648  ALA B C   1 
ATOM   8980  O O   . ALA B 1 648 ? 121.755 82.533  145.342 1.00 48.16  ? 648  ALA B O   1 
ATOM   8981  C CB  . ALA B 1 648 ? 119.345 82.339  144.073 1.00 48.16  ? 648  ALA B CB  1 
ATOM   8982  N N   . TYR B 1 649 ? 121.933 84.759  145.112 1.00 49.22  ? 649  TYR B N   1 
ATOM   8983  C CA  . TYR B 1 649 ? 123.279 84.822  145.657 1.00 49.22  ? 649  TYR B CA  1 
ATOM   8984  C C   . TYR B 1 649 ? 123.371 85.670  146.920 1.00 49.22  ? 649  TYR B C   1 
ATOM   8985  O O   . TYR B 1 649 ? 124.320 85.497  147.694 1.00 49.22  ? 649  TYR B O   1 
ATOM   8986  C CB  . TYR B 1 649 ? 124.256 85.349  144.592 1.00 49.22  ? 649  TYR B CB  1 
ATOM   8987  C CG  . TYR B 1 649 ? 125.695 85.434  145.048 1.00 49.22  ? 649  TYR B CG  1 
ATOM   8988  C CD1 . TYR B 1 649 ? 126.360 86.652  145.079 1.00 49.22  ? 649  TYR B CD1 1 
ATOM   8989  C CD2 . TYR B 1 649 ? 126.370 84.306  145.491 1.00 49.22  ? 649  TYR B CD2 1 
ATOM   8990  C CE1 . TYR B 1 649 ? 127.671 86.741  145.509 1.00 49.22  ? 649  TYR B CE1 1 
ATOM   8991  C CE2 . TYR B 1 649 ? 127.680 84.383  145.922 1.00 49.22  ? 649  TYR B CE2 1 
ATOM   8992  C CZ  . TYR B 1 649 ? 128.324 85.606  145.929 1.00 49.22  ? 649  TYR B CZ  1 
ATOM   8993  O OH  . TYR B 1 649 ? 129.626 85.703  146.357 1.00 49.22  ? 649  TYR B OH  1 
ATOM   8994  N N   . GLU B 1 650 ? 122.393 86.549  147.167 1.00 54.83  ? 650  GLU B N   1 
ATOM   8995  C CA  . GLU B 1 650 ? 122.365 87.326  148.406 1.00 54.83  ? 650  GLU B CA  1 
ATOM   8996  C C   . GLU B 1 650 ? 122.210 86.422  149.624 1.00 54.83  ? 650  GLU B C   1 
ATOM   8997  O O   . GLU B 1 650 ? 122.728 86.719  150.706 1.00 54.83  ? 650  GLU B O   1 
ATOM   8998  C CB  . GLU B 1 650 ? 121.240 88.357  148.343 1.00 54.83  ? 650  GLU B CB  1 
ATOM   8999  C CG  . GLU B 1 650 ? 119.935 87.819  147.775 1.00 54.83  ? 650  GLU B CG  1 
ATOM   9000  C CD  . GLU B 1 650 ? 119.046 87.178  148.818 1.00 54.83  ? 650  GLU B CD  1 
ATOM   9001  O OE1 . GLU B 1 650 ? 119.238 87.458  150.020 1.00 54.83  ? 650  GLU B OE1 1 
ATOM   9002  O OE2 . GLU B 1 650 ? 118.158 86.388  148.438 1.00 54.83  ? 650  GLU B OE2 1 
ATOM   9003  N N   . LYS B 1 651 ? 121.505 85.312  149.458 1.00 53.50  ? 651  LYS B N   1 
ATOM   9004  C CA  . LYS B 1 651 ? 121.530 84.204  150.393 1.00 53.50  ? 651  LYS B CA  1 
ATOM   9005  C C   . LYS B 1 651 ? 122.433 83.115  149.835 1.00 53.50  ? 651  LYS B C   1 
ATOM   9006  O O   . LYS B 1 651 ? 122.836 83.165  148.672 1.00 53.50  ? 651  LYS B O   1 
ATOM   9007  C CB  . LYS B 1 651 ? 120.121 83.663  150.627 1.00 53.50  ? 651  LYS B CB  1 
ATOM   9008  C CG  . LYS B 1 651 ? 119.350 83.419  149.346 1.00 53.50  ? 651  LYS B CG  1 
ATOM   9009  C CD  . LYS B 1 651 ? 118.073 82.653  149.611 1.00 53.50  ? 651  LYS B CD  1 
ATOM   9010  C CE  . LYS B 1 651 ? 118.381 81.296  150.213 1.00 53.50  ? 651  LYS B CE  1 
ATOM   9011  N NZ  . LYS B 1 651 ? 117.197 80.402  150.186 1.00 53.50  ? 651  LYS B NZ  1 
ATOM   9012  N N   . GLU B 1 652 ? 122.745 82.131  150.697 1.00 57.19  ? 652  GLU B N   1 
ATOM   9013  C CA  . GLU B 1 652 ? 123.561 80.931  150.408 1.00 57.19  ? 652  GLU B CA  1 
ATOM   9014  C C   . GLU B 1 652 ? 124.853 81.261  149.652 1.00 57.19  ? 652  GLU B C   1 
ATOM   9015  O O   . GLU B 1 652 ? 125.277 80.542  148.744 1.00 57.19  ? 652  GLU B O   1 
ATOM   9016  C CB  . GLU B 1 652 ? 122.738 79.820  149.725 1.00 57.19  ? 652  GLU B CB  1 
ATOM   9017  C CG  . GLU B 1 652 ? 122.084 80.069  148.366 1.00 57.19  ? 652  GLU B CG  1 
ATOM   9018  C CD  . GLU B 1 652 ? 121.106 78.981  147.990 1.00 57.19  ? 652  GLU B CD  1 
ATOM   9019  O OE1 . GLU B 1 652 ? 120.976 78.006  148.754 1.00 57.19  ? 652  GLU B OE1 1 
ATOM   9020  O OE2 . GLU B 1 652 ? 120.437 79.115  146.944 1.00 57.19  ? 652  GLU B OE2 1 
ATOM   9021  N N   . ARG B 1 653 ? 125.483 82.364  150.060 1.00 58.91  ? 653  ARG B N   1 
ATOM   9022  C CA  . ARG B 1 653 ? 126.763 82.813  149.527 1.00 58.91  ? 653  ARG B CA  1 
ATOM   9023  C C   . ARG B 1 653 ? 127.840 81.835  149.968 1.00 58.91  ? 653  ARG B C   1 
ATOM   9024  O O   . ARG B 1 653 ? 128.305 81.884  151.111 1.00 58.91  ? 653  ARG B O   1 
ATOM   9025  C CB  . ARG B 1 653 ? 127.053 84.221  150.036 1.00 58.91  ? 653  ARG B CB  1 
ATOM   9026  C CG  . ARG B 1 653 ? 128.263 84.920  149.444 1.00 58.91  ? 653  ARG B CG  1 
ATOM   9027  C CD  . ARG B 1 653 ? 128.646 86.103  150.325 1.00 58.91  ? 653  ARG B CD  1 
ATOM   9028  N NE  . ARG B 1 653 ? 129.551 87.043  149.669 1.00 58.91  ? 653  ARG B NE  1 
ATOM   9029  C CZ  . ARG B 1 653 ? 129.197 88.259  149.265 1.00 58.91  ? 653  ARG B CZ  1 
ATOM   9030  N NH1 . ARG B 1 653 ? 127.956 88.688  149.451 1.00 58.91  ? 653  ARG B NH1 1 
ATOM   9031  N NH2 . ARG B 1 653 ? 130.084 89.051  148.678 1.00 58.91  ? 653  ARG B NH2 1 
ATOM   9032  N N   . SER B 1 654 ? 128.231 80.944  149.067 1.00 54.31  ? 654  SER B N   1 
ATOM   9033  C CA  . SER B 1 654 ? 128.974 79.748  149.431 1.00 54.31  ? 654  SER B CA  1 
ATOM   9034  C C   . SER B 1 654 ? 129.712 79.264  148.189 1.00 54.31  ? 654  SER B C   1 
ATOM   9035  O O   . SER B 1 654 ? 129.946 80.040  147.257 1.00 54.31  ? 654  SER B O   1 
ATOM   9036  C CB  . SER B 1 654 ? 128.020 78.690  150.003 1.00 54.31  ? 654  SER B CB  1 
ATOM   9037  O OG  . SER B 1 654 ? 126.854 78.594  149.203 1.00 54.31  ? 654  SER B OG  1 
ATOM   9038  N N   . LEU B 1 655 ? 130.108 77.992  148.183 1.00 56.22  ? 655  LEU B N   1 
ATOM   9039  C CA  . LEU B 1 655 ? 130.501 77.318  146.952 1.00 56.22  ? 655  LEU B CA  1 
ATOM   9040  C C   . LEU B 1 655 ? 129.305 76.646  146.274 1.00 56.22  ? 655  LEU B C   1 
ATOM   9041  O O   . LEU B 1 655 ? 129.447 75.610  145.613 1.00 56.22  ? 655  LEU B O   1 
ATOM   9042  C CB  . LEU B 1 655 ? 131.622 76.314  147.237 1.00 56.22  ? 655  LEU B CB  1 
ATOM   9043  C CG  . LEU B 1 655 ? 132.614 75.946  146.119 1.00 56.22  ? 655  LEU B CG  1 
ATOM   9044  C CD1 . LEU B 1 655 ? 133.350 77.178  145.600 1.00 56.22  ? 655  LEU B CD1 1 
ATOM   9045  C CD2 . LEU B 1 655 ? 133.591 74.879  146.589 1.00 56.22  ? 655  LEU B CD2 1 
ATOM   9046  N N   . GLY B 1 656 ? 128.118 77.218  146.444 1.00 58.73  ? 656  GLY B N   1 
ATOM   9047  C CA  . GLY B 1 656 ? 126.895 76.758  145.823 1.00 58.73  ? 656  GLY B CA  1 
ATOM   9048  C C   . GLY B 1 656 ? 126.573 77.623  144.624 1.00 58.73  ? 656  GLY B C   1 
ATOM   9049  O O   . GLY B 1 656 ? 127.081 77.385  143.526 1.00 58.73  ? 656  GLY B O   1 
ATOM   9050  N N   . TRP B 1 657 ? 125.729 78.637  144.815 1.00 57.88  ? 657  TRP B N   1 
ATOM   9051  C CA  . TRP B 1 657 ? 125.357 79.554  143.737 1.00 57.88  ? 657  TRP B CA  1 
ATOM   9052  C C   . TRP B 1 657 ? 126.387 80.682  143.590 1.00 57.88  ? 657  TRP B C   1 
ATOM   9053  O O   . TRP B 1 657 ? 126.059 81.863  143.511 1.00 57.88  ? 657  TRP B O   1 
ATOM   9054  C CB  . TRP B 1 657 ? 123.965 80.124  143.989 1.00 57.88  ? 657  TRP B CB  1 
ATOM   9055  C CG  . TRP B 1 657 ? 122.817 79.131  144.093 1.00 57.88  ? 657  TRP B CG  1 
ATOM   9056  C CD1 . TRP B 1 657 ? 122.668 78.128  145.012 1.00 57.88  ? 657  TRP B CD1 1 
ATOM   9057  C CD2 . TRP B 1 657 ? 121.628 79.110  143.293 1.00 57.88  ? 657  TRP B CD2 1 
ATOM   9058  N NE1 . TRP B 1 657 ? 121.487 77.464  144.807 1.00 57.88  ? 657  TRP B NE1 1 
ATOM   9059  C CE2 . TRP B 1 657 ? 120.826 78.049  143.761 1.00 57.88  ? 657  TRP B CE2 1 
ATOM   9060  C CE3 . TRP B 1 657 ? 121.173 79.871  142.214 1.00 57.88  ? 657  TRP B CE3 1 
ATOM   9061  C CZ2 . TRP B 1 657 ? 119.596 77.734  143.189 1.00 57.88  ? 657  TRP B CZ2 1 
ATOM   9062  C CZ3 . TRP B 1 657 ? 119.950 79.559  141.649 1.00 57.88  ? 657  TRP B CZ3 1 
ATOM   9063  C CH2 . TRP B 1 657 ? 119.177 78.500  142.136 1.00 57.88  ? 657  TRP B CH2 1 
ATOM   9064  N N   . LEU B 1 658 ? 127.658 80.288  143.534 1.00 54.12  ? 658  LEU B N   1 
ATOM   9065  C CA  . LEU B 1 658 ? 128.771 81.162  143.184 1.00 54.12  ? 658  LEU B CA  1 
ATOM   9066  C C   . LEU B 1 658 ? 129.690 80.532  142.155 1.00 54.12  ? 658  LEU B C   1 
ATOM   9067  O O   . LEU B 1 658 ? 130.414 81.259  141.464 1.00 54.12  ? 658  LEU B O   1 
ATOM   9068  C CB  . LEU B 1 658 ? 129.576 81.538  144.436 1.00 54.12  ? 658  LEU B CB  1 
ATOM   9069  C CG  . LEU B 1 658 ? 130.767 82.502  144.431 1.00 54.12  ? 658  LEU B CG  1 
ATOM   9070  C CD1 . LEU B 1 658 ? 130.468 83.779  143.674 1.00 54.12  ? 658  LEU B CD1 1 
ATOM   9071  C CD2 . LEU B 1 658 ? 131.182 82.807  145.856 1.00 54.12  ? 658  LEU B CD2 1 
ATOM   9072  N N   . CYS B 1 659 ? 129.656 79.209  141.999 1.00 54.78  ? 659  CYS B N   1 
ATOM   9073  C CA  . CYS B 1 659 ? 130.072 78.554  140.770 1.00 54.78  ? 659  CYS B CA  1 
ATOM   9074  C C   . CYS B 1 659 ? 128.946 78.521  139.741 1.00 54.78  ? 659  CYS B C   1 
ATOM   9075  O O   . CYS B 1 659 ? 129.059 77.823  138.729 1.00 54.78  ? 659  CYS B O   1 
ATOM   9076  C CB  . CYS B 1 659 ? 130.563 77.135  141.061 1.00 54.78  ? 659  CYS B CB  1 
ATOM   9077  S SG  . CYS B 1 659 ? 129.274 75.990  141.597 1.00 54.78  ? 659  CYS B SG  1 
ATOM   9078  N N   . LEU B 1 660 ? 127.856 79.249  140.001 1.00 50.98  ? 660  LEU B N   1 
ATOM   9079  C CA  . LEU B 1 660 ? 126.768 79.440  139.061 1.00 50.98  ? 660  LEU B CA  1 
ATOM   9080  C C   . LEU B 1 660 ? 126.693 80.862  138.523 1.00 50.98  ? 660  LEU B C   1 
ATOM   9081  O O   . LEU B 1 660 ? 126.336 81.041  137.354 1.00 50.98  ? 660  LEU B O   1 
ATOM   9082  C CB  . LEU B 1 660 ? 125.426 79.079  139.721 1.00 50.98  ? 660  LEU B CB  1 
ATOM   9083  C CG  . LEU B 1 660 ? 124.337 78.421  138.872 1.00 50.98  ? 660  LEU B CG  1 
ATOM   9084  C CD1 . LEU B 1 660 ? 124.883 77.213  138.142 1.00 50.98  ? 660  LEU B CD1 1 
ATOM   9085  C CD2 . LEU B 1 660 ? 123.160 78.023  139.739 1.00 50.98  ? 660  LEU B CD2 1 
ATOM   9086  N N   . VAL B 1 661 ? 127.037 81.876  139.326 1.00 46.37  ? 661  VAL B N   1 
ATOM   9087  C CA  . VAL B 1 661 ? 127.082 83.251  138.844 1.00 46.37  ? 661  VAL B CA  1 
ATOM   9088  C C   . VAL B 1 661 ? 128.412 83.558  138.162 1.00 46.37  ? 661  VAL B C   1 
ATOM   9089  O O   . VAL B 1 661 ? 128.614 84.672  137.664 1.00 46.37  ? 661  VAL B O   1 
ATOM   9090  C CB  . VAL B 1 661 ? 126.792 84.213  140.019 1.00 46.37  ? 661  VAL B CB  1 
ATOM   9091  C CG1 . VAL B 1 661 ? 128.011 84.377  140.904 1.00 46.37  ? 661  VAL B CG1 1 
ATOM   9092  C CG2 . VAL B 1 661 ? 126.206 85.552  139.555 1.00 46.37  ? 661  VAL B CG2 1 
ATOM   9093  N N   . VAL B 1 662 ? 129.329 82.598  138.116 1.00 49.70  ? 662  VAL B N   1 
ATOM   9094  C CA  . VAL B 1 662 ? 130.508 82.716  137.270 1.00 49.70  ? 662  VAL B CA  1 
ATOM   9095  C C   . VAL B 1 662 ? 130.215 81.861  136.044 1.00 49.70  ? 662  VAL B C   1 
ATOM   9096  O O   . VAL B 1 662 ? 130.687 82.141  134.936 1.00 49.70  ? 662  VAL B O   1 
ATOM   9097  C CB  . VAL B 1 662 ? 131.778 82.281  138.027 1.00 49.70  ? 662  VAL B CB  1 
ATOM   9098  C CG1 . VAL B 1 662 ? 133.004 82.227  137.125 1.00 49.70  ? 662  VAL B CG1 1 
ATOM   9099  C CG2 . VAL B 1 662 ? 132.027 83.218  139.187 1.00 49.70  ? 662  VAL B CG2 1 
ATOM   9100  N N   . ALA B 1 663 ? 129.362 80.853  136.226 1.00 50.27  ? 663  ALA B N   1 
ATOM   9101  C CA  . ALA B 1 663 ? 128.990 79.971  135.126 1.00 50.27  ? 663  ALA B CA  1 
ATOM   9102  C C   . ALA B 1 663 ? 128.084 80.672  134.121 1.00 50.27  ? 663  ALA B C   1 
ATOM   9103  O O   . ALA B 1 663 ? 128.440 80.816  132.947 1.00 50.27  ? 663  ALA B O   1 
ATOM   9104  C CB  . ALA B 1 663 ? 128.304 78.716  135.667 1.00 50.27  ? 663  ALA B CB  1 
ATOM   9105  N N   . MET B 1 664 ? 126.908 81.120  134.566 1.00 45.52  ? 664  MET B N   1 
ATOM   9106  C CA  . MET B 1 664 ? 125.938 81.677  133.630 1.00 45.52  ? 664  MET B CA  1 
ATOM   9107  C C   . MET B 1 664 ? 126.321 83.077  133.176 1.00 45.52  ? 664  MET B C   1 
ATOM   9108  O O   . MET B 1 664 ? 125.856 83.530  132.129 1.00 45.52  ? 664  MET B O   1 
ATOM   9109  C CB  . MET B 1 664 ? 124.548 81.696  134.254 1.00 45.52  ? 664  MET B CB  1 
ATOM   9110  C CG  . MET B 1 664 ? 124.036 80.335  134.658 1.00 45.52  ? 664  MET B CG  1 
ATOM   9111  S SD  . MET B 1 664 ? 123.980 79.194  133.273 1.00 45.52  ? 664  MET B SD  1 
ATOM   9112  C CE  . MET B 1 664 ? 123.324 77.730  134.063 1.00 45.52  ? 664  MET B CE  1 
ATOM   9113  N N   . SER B 1 665 ? 127.165 83.771  133.930 1.00 38.95  ? 665  SER B N   1 
ATOM   9114  C CA  . SER B 1 665 ? 127.529 85.122  133.546 1.00 38.95  ? 665  SER B CA  1 
ATOM   9115  C C   . SER B 1 665 ? 128.683 85.168  132.563 1.00 38.95  ? 665  SER B C   1 
ATOM   9116  O O   . SER B 1 665 ? 128.929 86.227  131.983 1.00 38.95  ? 665  SER B O   1 
ATOM   9117  C CB  . SER B 1 665 ? 127.893 85.945  134.770 1.00 38.95  ? 665  SER B CB  1 
ATOM   9118  O OG  . SER B 1 665 ? 129.133 85.523  135.300 1.00 38.95  ? 665  SER B OG  1 
ATOM   9119  N N   . SER B 1 666 ? 129.402 84.068  132.363 1.00 33.29  ? 666  SER B N   1 
ATOM   9120  C CA  . SER B 1 666 ? 130.353 83.990  131.264 1.00 33.29  ? 666  SER B CA  1 
ATOM   9121  C C   . SER B 1 666 ? 129.805 83.212  130.082 1.00 33.29  ? 666  SER B C   1 
ATOM   9122  O O   . SER B 1 666 ? 130.347 83.328  128.980 1.00 33.29  ? 666  SER B O   1 
ATOM   9123  C CB  . SER B 1 666 ? 131.671 83.367  131.727 1.00 33.29  ? 666  SER B CB  1 
ATOM   9124  O OG  . SER B 1 666 ? 132.504 84.353  132.310 1.00 33.29  ? 666  SER B OG  1 
ATOM   9125  N N   . VAL B 1 667 ? 128.756 82.416  130.295 1.00 30.25  ? 667  VAL B N   1 
ATOM   9126  C CA  . VAL B 1 667 ? 127.958 81.905  129.185 1.00 30.25  ? 667  VAL B CA  1 
ATOM   9127  C C   . VAL B 1 667 ? 127.297 83.062  128.451 1.00 30.25  ? 667  VAL B C   1 
ATOM   9128  O O   . VAL B 1 667 ? 127.255 83.094  127.217 1.00 30.25  ? 667  VAL B O   1 
ATOM   9129  C CB  . VAL B 1 667 ? 126.928 80.882  129.702 1.00 30.25  ? 667  VAL B CB  1 
ATOM   9130  C CG1 . VAL B 1 667 ? 125.766 80.692  128.729 1.00 30.25  ? 667  VAL B CG1 1 
ATOM   9131  C CG2 . VAL B 1 667 ? 127.609 79.552  129.970 1.00 30.25  ? 667  VAL B CG2 1 
ATOM   9132  N N   . ALA B 1 668 ? 126.812 84.053  129.204 1.00 19.26  ? 668  ALA B N   1 
ATOM   9133  C CA  . ALA B 1 668 ? 126.180 85.218  128.597 1.00 19.26  ? 668  ALA B CA  1 
ATOM   9134  C C   . ALA B 1 668 ? 127.180 86.057  127.821 1.00 19.26  ? 668  ALA B C   1 
ATOM   9135  O O   . ALA B 1 668 ? 126.932 86.405  126.667 1.00 19.26  ? 668  ALA B O   1 
ATOM   9136  C CB  . ALA B 1 668 ? 125.501 86.068  129.666 1.00 19.26  ? 668  ALA B CB  1 
ATOM   9137  N N   . THR B 1 669 ? 128.348 86.321  128.404 1.00 21.48  ? 669  THR B N   1 
ATOM   9138  C CA  . THR B 1 669 ? 129.245 87.332  127.860 1.00 21.48  ? 669  THR B CA  1 
ATOM   9139  C C   . THR B 1 669 ? 129.971 86.856  126.599 1.00 21.48  ? 669  THR B C   1 
ATOM   9140  O O   . THR B 1 669 ? 130.601 87.665  125.915 1.00 21.48  ? 669  THR B O   1 
ATOM   9141  C CB  . THR B 1 669 ? 130.215 87.743  128.967 1.00 21.48  ? 669  THR B CB  1 
ATOM   9142  O OG1 . THR B 1 669 ? 129.470 87.878  130.177 1.00 21.48  ? 669  THR B OG1 1 
ATOM   9143  C CG2 . THR B 1 669 ? 130.839 89.109  128.712 1.00 21.48  ? 669  THR B CG2 1 
ATOM   9144  N N   . ILE B 1 670 ? 129.857 85.581  126.235 1.00 22.57  ? 670  ILE B N   1 
ATOM   9145  C CA  . ILE B 1 670 ? 130.264 85.156  124.897 1.00 22.57  ? 670  ILE B CA  1 
ATOM   9146  C C   . ILE B 1 670 ? 129.067 85.139  123.950 1.00 22.57  ? 670  ILE B C   1 
ATOM   9147  O O   . ILE B 1 670 ? 129.175 85.529  122.786 1.00 22.57  ? 670  ILE B O   1 
ATOM   9148  C CB  . ILE B 1 670 ? 130.984 83.784  124.956 1.00 22.57  ? 670  ILE B CB  1 
ATOM   9149  C CG1 . ILE B 1 670 ? 131.304 83.247  123.557 1.00 22.57  ? 670  ILE B CG1 1 
ATOM   9150  C CG2 . ILE B 1 670 ? 130.194 82.748  125.753 1.00 22.57  ? 670  ILE B CG2 1 
ATOM   9151  C CD1 . ILE B 1 670 ? 132.285 84.085  122.767 1.00 22.57  ? 670  ILE B CD1 1 
ATOM   9152  N N   . TYR B 1 671 ? 127.897 84.760  124.456 1.00 15.00  ? 671  TYR B N   1 
ATOM   9153  C CA  . TYR B 1 671 ? 126.680 84.667  123.670 1.00 15.00  ? 671  TYR B CA  1 
ATOM   9154  C C   . TYR B 1 671 ? 126.098 86.027  123.334 1.00 15.00  ? 671  TYR B C   1 
ATOM   9155  O O   . TYR B 1 671 ? 125.222 86.113  122.472 1.00 15.00  ? 671  TYR B O   1 
ATOM   9156  C CB  . TYR B 1 671 ? 125.722 83.778  124.438 1.00 15.00  ? 671  TYR B CB  1 
ATOM   9157  C CG  . TYR B 1 671 ? 124.453 83.406  123.766 1.00 15.00  ? 671  TYR B CG  1 
ATOM   9158  C CD1 . TYR B 1 671 ? 124.440 83.012  122.451 1.00 15.00  ? 671  TYR B CD1 1 
ATOM   9159  C CD2 . TYR B 1 671 ? 123.314 83.230  124.505 1.00 15.00  ? 671  TYR B CD2 1 
ATOM   9160  C CE1 . TYR B 1 671 ? 123.284 82.611  121.856 1.00 15.00  ? 671  TYR B CE1 1 
ATOM   9161  C CE2 . TYR B 1 671 ? 122.175 82.801  123.935 1.00 15.00  ? 671  TYR B CE2 1 
ATOM   9162  C CZ  . TYR B 1 671 ? 122.155 82.506  122.607 1.00 15.00  ? 671  TYR B CZ  1 
ATOM   9163  O OH  . TYR B 1 671 ? 120.990 82.085  122.029 1.00 15.00  ? 671  TYR B OH  1 
ATOM   9164  N N   . GLN B 1 672 ? 126.550 87.086  123.995 1.00 14.12  ? 672  GLN B N   1 
ATOM   9165  C CA  . GLN B 1 672 ? 126.413 88.422  123.444 1.00 14.12  ? 672  GLN B CA  1 
ATOM   9166  C C   . GLN B 1 672 ? 127.582 88.805  122.558 1.00 14.12  ? 672  GLN B C   1 
ATOM   9167  O O   . GLN B 1 672 ? 127.376 89.510  121.572 1.00 14.12  ? 672  GLN B O   1 
ATOM   9168  C CB  . GLN B 1 672 ? 126.281 89.466  124.554 1.00 14.12  ? 672  GLN B CB  1 
ATOM   9169  C CG  . GLN B 1 672 ? 125.423 89.060  125.728 1.00 14.12  ? 672  GLN B CG  1 
ATOM   9170  C CD  . GLN B 1 672 ? 123.973 89.384  125.537 1.00 14.12  ? 672  GLN B CD  1 
ATOM   9171  O OE1 . GLN B 1 672 ? 123.637 90.362  124.895 1.00 14.12  ? 672  GLN B OE1 1 
ATOM   9172  N NE2 . GLN B 1 672 ? 123.099 88.569  126.102 1.00 14.12  ? 672  GLN B NE2 1 
ATOM   9173  N N   . LEU B 1 673 ? 128.800 88.360  122.876 1.00 17.43  ? 673  LEU B N   1 
ATOM   9174  C CA  . LEU B 1 673 ? 129.978 88.651  122.061 1.00 17.43  ? 673  LEU B CA  1 
ATOM   9175  C C   . LEU B 1 673 ? 130.008 87.908  120.739 1.00 17.43  ? 673  LEU B C   1 
ATOM   9176  O O   . LEU B 1 673 ? 130.634 88.395  119.794 1.00 17.43  ? 673  LEU B O   1 
ATOM   9177  C CB  . LEU B 1 673 ? 131.256 88.311  122.814 1.00 17.43  ? 673  LEU B CB  1 
ATOM   9178  C CG  . LEU B 1 673 ? 132.111 89.396  123.437 1.00 17.43  ? 673  LEU B CG  1 
ATOM   9179  C CD1 . LEU B 1 673 ? 132.879 90.073  122.362 1.00 17.43  ? 673  LEU B CD1 1 
ATOM   9180  C CD2 . LEU B 1 673 ? 131.249 90.395  124.071 1.00 17.43  ? 673  LEU B CD2 1 
ATOM   9181  N N   . TYR B 1 674 ? 129.407 86.725  120.665 1.00 19.78  ? 674  TYR B N   1 
ATOM   9182  C CA  . TYR B 1 674 ? 129.277 86.031  119.387 1.00 19.78  ? 674  TYR B CA  1 
ATOM   9183  C C   . TYR B 1 674 ? 128.350 86.809  118.464 1.00 19.78  ? 674  TYR B C   1 
ATOM   9184  O O   . TYR B 1 674 ? 128.722 87.163  117.343 1.00 19.78  ? 674  TYR B O   1 
ATOM   9185  C CB  . TYR B 1 674 ? 128.763 84.608  119.624 1.00 19.78  ? 674  TYR B CB  1 
ATOM   9186  C CG  . TYR B 1 674 ? 128.039 83.987  118.454 1.00 19.78  ? 674  TYR B CG  1 
ATOM   9187  C CD1 . TYR B 1 674 ? 128.720 83.642  117.296 1.00 19.78  ? 674  TYR B CD1 1 
ATOM   9188  C CD2 . TYR B 1 674 ? 126.676 83.732  118.516 1.00 19.78  ? 674  TYR B CD2 1 
ATOM   9189  C CE1 . TYR B 1 674 ? 128.068 83.077  116.235 1.00 19.78  ? 674  TYR B CE1 1 
ATOM   9190  C CE2 . TYR B 1 674 ? 126.016 83.163  117.460 1.00 19.78  ? 674  TYR B CE2 1 
ATOM   9191  C CZ  . TYR B 1 674 ? 126.718 82.838  116.322 1.00 19.78  ? 674  TYR B CZ  1 
ATOM   9192  O OH  . TYR B 1 674 ? 126.069 82.269  115.256 1.00 19.78  ? 674  TYR B OH  1 
ATOM   9193  N N   . TRP B 1 675 ? 127.145 87.096  118.944 1.00 18.47  ? 675  TRP B N   1 
ATOM   9194  C CA  . TRP B 1 675 ? 126.068 87.681  118.162 1.00 18.47  ? 675  TRP B CA  1 
ATOM   9195  C C   . TRP B 1 675 ? 126.363 89.080  117.663 1.00 18.47  ? 675  TRP B C   1 
ATOM   9196  O O   . TRP B 1 675 ? 125.786 89.514  116.664 1.00 18.47  ? 675  TRP B O   1 
ATOM   9197  C CB  . TRP B 1 675 ? 124.809 87.731  118.998 1.00 18.47  ? 675  TRP B CB  1 
ATOM   9198  C CG  . TRP B 1 675 ? 123.592 87.795  118.209 1.00 18.47  ? 675  TRP B CG  1 
ATOM   9199  C CD1 . TRP B 1 675 ? 122.927 88.905  117.806 1.00 18.47  ? 675  TRP B CD1 1 
ATOM   9200  C CD2 . TRP B 1 675 ? 122.866 86.689  117.721 1.00 18.47  ? 675  TRP B CD2 1 
ATOM   9201  N NE1 . TRP B 1 675 ? 121.822 88.555  117.087 1.00 18.47  ? 675  TRP B NE1 1 
ATOM   9202  C CE2 . TRP B 1 675 ? 121.763 87.191  117.021 1.00 18.47  ? 675  TRP B CE2 1 
ATOM   9203  C CE3 . TRP B 1 675 ? 123.043 85.313  117.807 1.00 18.47  ? 675  TRP B CE3 1 
ATOM   9204  C CZ2 . TRP B 1 675 ? 120.847 86.364  116.398 1.00 18.47  ? 675  TRP B CZ2 1 
ATOM   9205  C CZ3 . TRP B 1 675 ? 122.140 84.500  117.197 1.00 18.47  ? 675  TRP B CZ3 1 
ATOM   9206  C CH2 . TRP B 1 675 ? 121.045 85.020  116.507 1.00 18.47  ? 675  TRP B CH2 1 
ATOM   9207  N N   . ASP B 1 676 ? 127.225 89.801  118.373 1.00 23.95  ? 676  ASP B N   1 
ATOM   9208  C CA  . ASP B 1 676 ? 127.541 91.165  117.984 1.00 23.95  ? 676  ASP B CA  1 
ATOM   9209  C C   . ASP B 1 676 ? 128.305 91.189  116.674 1.00 23.95  ? 676  ASP B C   1 
ATOM   9210  O O   . ASP B 1 676 ? 127.873 91.819  115.705 1.00 23.95  ? 676  ASP B O   1 
ATOM   9211  C CB  . ASP B 1 676 ? 128.336 91.848  119.085 1.00 23.95  ? 676  ASP B CB  1 
ATOM   9212  C CG  . ASP B 1 676 ? 127.454 92.363  120.193 1.00 23.95  ? 676  ASP B CG  1 
ATOM   9213  O OD1 . ASP B 1 676 ? 126.243 92.063  120.192 1.00 23.95  ? 676  ASP B OD1 1 
ATOM   9214  O OD2 . ASP B 1 676 ? 127.974 93.076  121.068 1.00 23.95  ? 676  ASP B OD2 1 
ATOM   9215  N N   . PHE B 1 677 ? 129.419 90.462  116.607 1.00 19.03  ? 677  PHE B N   1 
ATOM   9216  C CA  . PHE B 1 677 ? 130.220 90.438  115.388 1.00 19.03  ? 677  PHE B CA  1 
ATOM   9217  C C   . PHE B 1 677 ? 129.601 89.600  114.282 1.00 19.03  ? 677  PHE B C   1 
ATOM   9218  O O   . PHE B 1 677 ? 129.714 89.962  113.108 1.00 19.03  ? 677  PHE B O   1 
ATOM   9219  C CB  . PHE B 1 677 ? 131.613 89.911  115.689 1.00 19.03  ? 677  PHE B CB  1 
ATOM   9220  C CG  . PHE B 1 677 ? 132.314 90.679  116.731 1.00 19.03  ? 677  PHE B CG  1 
ATOM   9221  C CD1 . PHE B 1 677 ? 132.662 91.988  116.513 1.00 19.03  ? 677  PHE B CD1 1 
ATOM   9222  C CD2 . PHE B 1 677 ? 132.601 90.106  117.941 1.00 19.03  ? 677  PHE B CD2 1 
ATOM   9223  C CE1 . PHE B 1 677 ? 133.303 92.708  117.480 1.00 19.03  ? 677  PHE B CE1 1 
ATOM   9224  C CE2 . PHE B 1 677 ? 133.242 90.819  118.909 1.00 19.03  ? 677  PHE B CE2 1 
ATOM   9225  C CZ  . PHE B 1 677 ? 133.592 92.124  118.680 1.00 19.03  ? 677  PHE B CZ  1 
ATOM   9226  N N   . VAL B 1 678 ? 128.955 88.495  114.619 1.00 22.99  ? 678  VAL B N   1 
ATOM   9227  C CA  . VAL B 1 678 ? 128.568 87.558  113.584 1.00 22.99  ? 678  VAL B CA  1 
ATOM   9228  C C   . VAL B 1 678 ? 127.236 87.969  112.988 1.00 22.99  ? 678  VAL B C   1 
ATOM   9229  O O   . VAL B 1 678 ? 127.153 88.250  111.790 1.00 22.99  ? 678  VAL B O   1 
ATOM   9230  C CB  . VAL B 1 678 ? 128.526 86.124  114.126 1.00 22.99  ? 678  VAL B CB  1 
ATOM   9231  C CG1 . VAL B 1 678 ? 127.981 85.193  113.073 1.00 22.99  ? 678  VAL B CG1 1 
ATOM   9232  C CG2 . VAL B 1 678 ? 129.916 85.705  114.529 1.00 22.99  ? 678  VAL B CG2 1 
ATOM   9233  N N   . LYS B 1 679 ? 126.185 88.022  113.796 1.00 19.93  ? 679  LYS B N   1 
ATOM   9234  C CA  . LYS B 1 679 ? 124.852 88.183  113.238 1.00 19.93  ? 679  LYS B CA  1 
ATOM   9235  C C   . LYS B 1 679 ? 124.300 89.591  113.378 1.00 19.93  ? 679  LYS B C   1 
ATOM   9236  O O   . LYS B 1 679 ? 123.157 89.834  112.975 1.00 19.93  ? 679  LYS B O   1 
ATOM   9237  C CB  . LYS B 1 679 ? 123.897 87.176  113.862 1.00 19.93  ? 679  LYS B CB  1 
ATOM   9238  C CG  . LYS B 1 679 ? 124.064 85.800  113.284 1.00 19.93  ? 679  LYS B CG  1 
ATOM   9239  C CD  . LYS B 1 679 ? 122.787 85.016  113.358 1.00 19.93  ? 679  LYS B CD  1 
ATOM   9240  C CE  . LYS B 1 679 ? 122.968 83.670  112.707 1.00 19.93  ? 679  LYS B CE  1 
ATOM   9241  N NZ  . LYS B 1 679 ? 124.265 83.059  113.108 1.00 19.93  ? 679  LYS B NZ  1 
ATOM   9242  N N   . ASP B 1 680 ? 125.070 90.523  113.939 1.00 20.79  ? 680  ASP B N   1 
ATOM   9243  C CA  . ASP B 1 680 ? 124.693 91.931  113.925 1.00 20.79  ? 680  ASP B CA  1 
ATOM   9244  C C   . ASP B 1 680 ? 125.654 92.772  113.107 1.00 20.79  ? 680  ASP B C   1 
ATOM   9245  O O   . ASP B 1 680 ? 125.227 93.430  112.158 1.00 20.79  ? 680  ASP B O   1 
ATOM   9246  C CB  . ASP B 1 680 ? 124.591 92.490  115.350 1.00 20.79  ? 680  ASP B CB  1 
ATOM   9247  C CG  . ASP B 1 680 ? 123.186 92.396  115.906 1.00 20.79  ? 680  ASP B CG  1 
ATOM   9248  O OD1 . ASP B 1 680 ? 122.268 92.080  115.126 1.00 20.79  ? 680  ASP B OD1 1 
ATOM   9249  O OD2 . ASP B 1 680 ? 122.990 92.628  117.114 1.00 20.79  ? 680  ASP B OD2 1 
ATOM   9250  N N   . TRP B 1 681 ? 126.944 92.748  113.420 1.00 31.70  ? 681  TRP B N   1 
ATOM   9251  C CA  . TRP B 1 681 ? 127.894 93.516  112.630 1.00 31.70  ? 681  TRP B CA  1 
ATOM   9252  C C   . TRP B 1 681 ? 128.228 92.833  111.317 1.00 31.70  ? 681  TRP B C   1 
ATOM   9253  O O   . TRP B 1 681 ? 128.760 93.485  110.414 1.00 31.70  ? 681  TRP B O   1 
ATOM   9254  C CB  . TRP B 1 681 ? 129.197 93.771  113.398 1.00 31.70  ? 681  TRP B CB  1 
ATOM   9255  C CG  . TRP B 1 681 ? 129.081 94.578  114.677 1.00 31.70  ? 681  TRP B CG  1 
ATOM   9256  C CD1 . TRP B 1 681 ? 127.947 94.887  115.364 1.00 31.70  ? 681  TRP B CD1 1 
ATOM   9257  C CD2 . TRP B 1 681 ? 130.157 95.159  115.419 1.00 31.70  ? 681  TRP B CD2 1 
ATOM   9258  N NE1 . TRP B 1 681 ? 128.247 95.612  116.479 1.00 31.70  ? 681  TRP B NE1 1 
ATOM   9259  C CE2 . TRP B 1 681 ? 129.599 95.795  116.534 1.00 31.70  ? 681  TRP B CE2 1 
ATOM   9260  C CE3 . TRP B 1 681 ? 131.539 95.201  115.247 1.00 31.70  ? 681  TRP B CE3 1 
ATOM   9261  C CZ2 . TRP B 1 681 ? 130.365 96.463  117.465 1.00 31.70  ? 681  TRP B CZ2 1 
ATOM   9262  C CZ3 . TRP B 1 681 ? 132.296 95.868  116.177 1.00 31.70  ? 681  TRP B CZ3 1 
ATOM   9263  C CH2 . TRP B 1 681 ? 131.707 96.489  117.268 1.00 31.70  ? 681  TRP B CH2 1 
ATOM   9264  N N   . GLY B 1 682 ? 127.933 91.541  111.192 1.00 30.14  ? 682  GLY B N   1 
ATOM   9265  C CA  . GLY B 1 682 ? 128.201 90.793  109.984 1.00 30.14  ? 682  GLY B CA  1 
ATOM   9266  C C   . GLY B 1 682 ? 129.636 90.379  109.794 1.00 30.14  ? 682  GLY B C   1 
ATOM   9267  O O   . GLY B 1 682 ? 129.975 89.849  108.733 1.00 30.14  ? 682  GLY B O   1 
ATOM   9268  N N   . LEU B 1 683 ? 130.487 90.591  110.786 1.00 39.90  ? 683  LEU B N   1 
ATOM   9269  C CA  . LEU B 1 683 ? 131.915 90.383  110.633 1.00 39.90  ? 683  LEU B CA  1 
ATOM   9270  C C   . LEU B 1 683 ? 132.271 88.936  110.961 1.00 39.90  ? 683  LEU B C   1 
ATOM   9271  O O   . LEU B 1 683 ? 131.395 88.073  111.067 1.00 39.90  ? 683  LEU B O   1 
ATOM   9272  C CB  . LEU B 1 683 ? 132.676 91.373  111.506 1.00 39.90  ? 683  LEU B CB  1 
ATOM   9273  C CG  . LEU B 1 683 ? 132.425 92.825  111.128 1.00 39.90  ? 683  LEU B CG  1 
ATOM   9274  C CD1 . LEU B 1 683 ? 133.016 93.751  112.161 1.00 39.90  ? 683  LEU B CD1 1 
ATOM   9275  C CD2 . LEU B 1 683 ? 133.015 93.102  109.770 1.00 39.90  ? 683  LEU B CD2 1 
ATOM   9276  N N   . LEU B 1 684 ? 133.579 88.674  111.100 1.00 47.39  ? 684  LEU B N   1 
ATOM   9277  C CA  . LEU B 1 684 ? 134.149 87.369  111.461 1.00 47.39  ? 684  LEU B CA  1 
ATOM   9278  C C   . LEU B 1 684 ? 133.764 86.277  110.466 1.00 47.39  ? 684  LEU B C   1 
ATOM   9279  O O   . LEU B 1 684 ? 133.272 85.213  110.843 1.00 47.39  ? 684  LEU B O   1 
ATOM   9280  C CB  . LEU B 1 684 ? 133.774 86.956  112.887 1.00 47.39  ? 684  LEU B CB  1 
ATOM   9281  C CG  . LEU B 1 684 ? 134.461 87.680  114.041 1.00 47.39  ? 684  LEU B CG  1 
ATOM   9282  C CD1 . LEU B 1 684 ? 134.220 86.926  115.326 1.00 47.39  ? 684  LEU B CD1 1 
ATOM   9283  C CD2 . LEU B 1 684 ? 135.940 87.813  113.783 1.00 47.39  ? 684  LEU B CD2 1 
ATOM   9284  N N   . GLN B 1 685 ? 133.985 86.540  109.185 1.00 61.67  ? 685  GLN B N   1 
ATOM   9285  C CA  . GLN B 1 685 ? 133.784 85.543  108.143 1.00 61.67  ? 685  GLN B CA  1 
ATOM   9286  C C   . GLN B 1 685 ? 135.152 85.108  107.632 1.00 61.67  ? 685  GLN B C   1 
ATOM   9287  O O   . GLN B 1 685 ? 135.833 85.873  106.941 1.00 61.67  ? 685  GLN B O   1 
ATOM   9288  C CB  . GLN B 1 685 ? 132.918 86.101  107.019 1.00 61.67  ? 685  GLN B CB  1 
ATOM   9289  C CG  . GLN B 1 685 ? 131.538 86.524  107.480 1.00 61.67  ? 685  GLN B CG  1 
ATOM   9290  C CD  . GLN B 1 685 ? 130.598 86.807  106.329 1.00 61.67  ? 685  GLN B CD  1 
ATOM   9291  O OE1 . GLN B 1 685 ? 130.953 86.627  105.165 1.00 61.67  ? 685  GLN B OE1 1 
ATOM   9292  N NE2 . GLN B 1 685 ? 129.389 87.255  106.649 1.00 61.67  ? 685  GLN B NE2 1 
ATOM   9293  N N   . HIS B 1 686 ? 135.558 83.881  107.982 1.00 62.32  ? 686  HIS B N   1 
ATOM   9294  C CA  . HIS B 1 686 ? 136.846 83.353  107.539 1.00 62.32  ? 686  HIS B CA  1 
ATOM   9295  C C   . HIS B 1 686 ? 136.878 83.093  106.041 1.00 62.32  ? 686  HIS B C   1 
ATOM   9296  O O   . HIS B 1 686 ? 137.952 83.141  105.432 1.00 62.32  ? 686  HIS B O   1 
ATOM   9297  C CB  . HIS B 1 686 ? 137.187 82.061  108.285 1.00 62.32  ? 686  HIS B CB  1 
ATOM   9298  C CG  . HIS B 1 686 ? 137.881 82.279  109.593 1.00 62.32  ? 686  HIS B CG  1 
ATOM   9299  N ND1 . HIS B 1 686 ? 138.144 81.251  110.473 1.00 62.32  ? 686  HIS B ND1 1 
ATOM   9300  C CD2 . HIS B 1 686 ? 138.371 83.401  110.170 1.00 62.32  ? 686  HIS B CD2 1 
ATOM   9301  C CE1 . HIS B 1 686 ? 138.764 81.731  111.535 1.00 62.32  ? 686  HIS B CE1 1 
ATOM   9302  N NE2 . HIS B 1 686 ? 138.913 83.034  111.377 1.00 62.32  ? 686  HIS B NE2 1 
ATOM   9303  N N   . ASN B 1 687 ? 135.724 82.825  105.432 1.00 59.91  ? 687  ASN B N   1 
ATOM   9304  C CA  . ASN B 1 687 ? 135.638 82.605  103.990 1.00 59.91  ? 687  ASN B CA  1 
ATOM   9305  C C   . ASN B 1 687 ? 135.500 83.959  103.292 1.00 59.91  ? 687  ASN B C   1 
ATOM   9306  O O   . ASN B 1 687 ? 134.463 84.312  102.726 1.00 59.91  ? 687  ASN B O   1 
ATOM   9307  C CB  . ASN B 1 687 ? 134.476 81.677  103.664 1.00 59.91  ? 687  ASN B CB  1 
ATOM   9308  C CG  . ASN B 1 687 ? 134.401 80.480  104.602 1.00 59.91  ? 687  ASN B CG  1 
ATOM   9309  O OD1 . ASN B 1 687 ? 133.329 80.138  105.104 1.00 59.91  ? 687  ASN B OD1 1 
ATOM   9310  N ND2 . ASN B 1 687 ? 135.538 79.833  104.832 1.00 59.91  ? 687  ASN B ND2 1 
ATOM   9311  N N   . SER B 1 688 ? 136.584 84.729  103.349 1.00 57.88  ? 688  SER B N   1 
ATOM   9312  C CA  . SER B 1 688 ? 136.616 86.084  102.815 1.00 57.88  ? 688  SER B CA  1 
ATOM   9313  C C   . SER B 1 688 ? 138.040 86.406  102.390 1.00 57.88  ? 688  SER B C   1 
ATOM   9314  O O   . SER B 1 688 ? 138.974 85.640  102.636 1.00 57.88  ? 688  SER B O   1 
ATOM   9315  C CB  . SER B 1 688 ? 136.126 87.117  103.837 1.00 57.88  ? 688  SER B CB  1 
ATOM   9316  O OG  . SER B 1 688 ? 134.903 86.741  104.442 1.00 57.88  ? 688  SER B OG  1 
ATOM   9317  N N   . ASN B 1 689 ? 138.190 87.558  101.744 1.00 55.57  ? 689  ASN B N   1 
ATOM   9318  C CA  . ASN B 1 689 ? 139.495 88.064  101.348 1.00 55.57  ? 689  ASN B CA  1 
ATOM   9319  C C   . ASN B 1 689 ? 140.141 88.930  102.419 1.00 55.57  ? 689  ASN B C   1 
ATOM   9320  O O   . ASN B 1 689 ? 141.283 89.364  102.241 1.00 55.57  ? 689  ASN B O   1 
ATOM   9321  C CB  . ASN B 1 689 ? 139.374 88.861  100.048 1.00 55.57  ? 689  ASN B CB  1 
ATOM   9322  C CG  . ASN B 1 689 ? 138.282 89.904  100.110 1.00 55.57  ? 689  ASN B CG  1 
ATOM   9323  O OD1 . ASN B 1 689 ? 137.221 89.670  100.686 1.00 55.57  ? 689  ASN B OD1 1 
ATOM   9324  N ND2 . ASN B 1 689 ? 138.537 91.064  99.521  1.00 55.57  ? 689  ASN B ND2 1 
ATOM   9325  N N   . ASN B 1 690 ? 139.446 89.184  103.521 1.00 56.19  ? 690  ASN B N   1 
ATOM   9326  C CA  . ASN B 1 690 ? 139.948 89.998  104.611 1.00 56.19  ? 690  ASN B CA  1 
ATOM   9327  C C   . ASN B 1 690 ? 140.020 89.163  105.879 1.00 56.19  ? 690  ASN B C   1 
ATOM   9328  O O   . ASN B 1 690 ? 139.094 88.400  106.175 1.00 56.19  ? 690  ASN B O   1 
ATOM   9329  C CB  . ASN B 1 690 ? 139.050 91.221  104.846 1.00 56.19  ? 690  ASN B CB  1 
ATOM   9330  C CG  . ASN B 1 690 ? 139.384 92.373  103.923 1.00 56.19  ? 690  ASN B CG  1 
ATOM   9331  O OD1 . ASN B 1 690 ? 140.549 92.711  103.733 1.00 56.19  ? 690  ASN B OD1 1 
ATOM   9332  N ND2 . ASN B 1 690 ? 138.359 92.979  103.336 1.00 56.19  ? 690  ASN B ND2 1 
ATOM   9333  N N   . PRO B 1 691 ? 141.117 89.276  106.641 1.00 61.61  ? 691  PRO B N   1 
ATOM   9334  C CA  . PRO B 1 691 ? 141.240 88.488  107.875 1.00 61.61  ? 691  PRO B CA  1 
ATOM   9335  C C   . PRO B 1 691 ? 140.300 88.978  108.962 1.00 61.61  ? 691  PRO B C   1 
ATOM   9336  O O   . PRO B 1 691 ? 140.379 90.136  109.380 1.00 61.61  ? 691  PRO B O   1 
ATOM   9337  C CB  . PRO B 1 691 ? 142.711 88.674  108.270 1.00 61.61  ? 691  PRO B CB  1 
ATOM   9338  C CG  . PRO B 1 691 ? 143.124 89.948  107.629 1.00 61.61  ? 691  PRO B CG  1 
ATOM   9339  C CD  . PRO B 1 691 ? 142.321 90.081  106.369 1.00 61.61  ? 691  PRO B CD  1 
ATOM   9340  N N   . TRP B 1 692 ? 139.368 88.113  109.369 1.00 64.76  ? 692  TRP B N   1 
ATOM   9341  C CA  . TRP B 1 692 ? 138.384 88.294  110.438 1.00 64.76  ? 692  TRP B CA  1 
ATOM   9342  C C   . TRP B 1 692 ? 137.369 89.407  110.174 1.00 64.76  ? 692  TRP B C   1 
ATOM   9343  O O   . TRP B 1 692 ? 136.599 89.738  111.078 1.00 64.76  ? 692  TRP B O   1 
ATOM   9344  C CB  . TRP B 1 692 ? 139.046 88.532  111.803 1.00 64.76  ? 692  TRP B CB  1 
ATOM   9345  C CG  . TRP B 1 692 ? 139.848 87.360  112.278 1.00 64.76  ? 692  TRP B CG  1 
ATOM   9346  C CD1 . TRP B 1 692 ? 139.778 86.080  111.814 1.00 64.76  ? 692  TRP B CD1 1 
ATOM   9347  C CD2 . TRP B 1 692 ? 140.829 87.355  113.321 1.00 64.76  ? 692  TRP B CD2 1 
ATOM   9348  N NE1 . TRP B 1 692 ? 140.658 85.279  112.498 1.00 64.76  ? 692  TRP B NE1 1 
ATOM   9349  C CE2 . TRP B 1 692 ? 141.315 86.037  113.430 1.00 64.76  ? 692  TRP B CE2 1 
ATOM   9350  C CE3 . TRP B 1 692 ? 141.345 88.336  114.173 1.00 64.76  ? 692  TRP B CE3 1 
ATOM   9351  C CZ2 . TRP B 1 692 ? 142.292 85.675  114.354 1.00 64.76  ? 692  TRP B CZ2 1 
ATOM   9352  C CZ3 . TRP B 1 692 ? 142.314 87.975  115.092 1.00 64.76  ? 692  TRP B CZ3 1 
ATOM   9353  C CH2 . TRP B 1 692 ? 142.778 86.655  115.175 1.00 64.76  ? 692  TRP B CH2 1 
ATOM   9354  N N   . LEU B 1 693 ? 137.344 89.996  108.981 1.00 54.79  ? 693  LEU B N   1 
ATOM   9355  C CA  . LEU B 1 693 ? 136.298 90.906  108.546 1.00 54.79  ? 693  LEU B CA  1 
ATOM   9356  C C   . LEU B 1 693 ? 135.492 90.238  107.435 1.00 54.79  ? 693  LEU B C   1 
ATOM   9357  O O   . LEU B 1 693 ? 135.689 89.062  107.118 1.00 54.79  ? 693  LEU B O   1 
ATOM   9358  C CB  . LEU B 1 693 ? 136.899 92.231  108.085 1.00 54.79  ? 693  LEU B CB  1 
ATOM   9359  C CG  . LEU B 1 693 ? 137.786 92.947  109.096 1.00 54.79  ? 693  LEU B CG  1 
ATOM   9360  C CD1 . LEU B 1 693 ? 138.291 94.249  108.523 1.00 54.79  ? 693  LEU B CD1 1 
ATOM   9361  C CD2 . LEU B 1 693 ? 137.019 93.191  110.365 1.00 54.79  ? 693  LEU B CD2 1 
ATOM   9362  N N   . ARG B 1 694 ? 134.574 90.982  106.833 1.00 41.73  ? 694  ARG B N   1 
ATOM   9363  C CA  . ARG B 1 694 ? 133.778 90.467  105.733 1.00 41.73  ? 694  ARG B CA  1 
ATOM   9364  C C   . ARG B 1 694 ? 134.434 90.830  104.407 1.00 41.73  ? 694  ARG B C   1 
ATOM   9365  O O   . ARG B 1 694 ? 135.582 91.284  104.360 1.00 41.73  ? 694  ARG B O   1 
ATOM   9366  C CB  . ARG B 1 694 ? 132.345 90.989  105.810 1.00 41.73  ? 694  ARG B CB  1 
ATOM   9367  C CG  . ARG B 1 694 ? 132.225 92.490  105.933 1.00 41.73  ? 694  ARG B CG  1 
ATOM   9368  C CD  . ARG B 1 694 ? 130.781 92.862  106.153 1.00 41.73  ? 694  ARG B CD  1 
ATOM   9369  N NE  . ARG B 1 694 ? 130.615 94.173  106.764 1.00 41.73  ? 694  ARG B NE  1 
ATOM   9370  C CZ  . ARG B 1 694 ? 129.523 94.521  107.430 1.00 41.73  ? 694  ARG B CZ  1 
ATOM   9371  N NH1 . ARG B 1 694 ? 128.545 93.644  107.558 1.00 41.73  ? 694  ARG B NH1 1 
ATOM   9372  N NH2 . ARG B 1 694 ? 129.409 95.723  107.973 1.00 41.73  ? 694  ARG B NH2 1 
ATOM   9373  N N   . ASN B 1 695 ? 133.699 90.612  103.317 1.00 46.29  ? 695  ASN B N   1 
ATOM   9374  C CA  . ASN B 1 695 ? 134.234 90.880  101.988 1.00 46.29  ? 695  ASN B CA  1 
ATOM   9375  C C   . ASN B 1 695 ? 134.284 92.375  101.704 1.00 46.29  ? 695  ASN B C   1 
ATOM   9376  O O   . ASN B 1 695 ? 135.360 92.951  101.511 1.00 46.29  ? 695  ASN B O   1 
ATOM   9377  C CB  . ASN B 1 695 ? 133.382 90.178  100.929 1.00 46.29  ? 695  ASN B CB  1 
ATOM   9378  C CG  . ASN B 1 695 ? 133.553 88.680  100.944 1.00 46.29  ? 695  ASN B CG  1 
ATOM   9379  O OD1 . ASN B 1 695 ? 134.563 88.165  101.410 1.00 46.29  ? 695  ASN B OD1 1 
ATOM   9380  N ND2 . ASN B 1 695 ? 132.560 87.967  100.424 1.00 46.29  ? 695  ASN B ND2 1 
ATOM   9381  N N   . GLN B 1 696 ? 133.122 93.017  101.688 1.00 38.76  ? 696  GLN B N   1 
ATOM   9382  C CA  . GLN B 1 696 ? 132.992 94.406  101.276 1.00 38.76  ? 696  GLN B CA  1 
ATOM   9383  C C   . GLN B 1 696 ? 132.879 95.284  102.517 1.00 38.76  ? 696  GLN B C   1 
ATOM   9384  O O   . GLN B 1 696 ? 132.245 94.898  103.506 1.00 38.76  ? 696  GLN B O   1 
ATOM   9385  C CB  . GLN B 1 696 ? 131.788 94.591  100.348 1.00 38.76  ? 696  GLN B CB  1 
ATOM   9386  C CG  . GLN B 1 696 ? 130.409 94.321  100.956 1.00 38.76  ? 696  GLN B CG  1 
ATOM   9387  C CD  . GLN B 1 696 ? 130.051 92.849  101.020 1.00 38.76  ? 696  GLN B CD  1 
ATOM   9388  O OE1 . GLN B 1 696 ? 130.394 92.075  100.129 1.00 38.76  ? 696  GLN B OE1 1 
ATOM   9389  N NE2 . GLN B 1 696 ? 129.364 92.455  102.083 1.00 38.76  ? 696  GLN B NE2 1 
ATOM   9390  N N   . LEU B 1 697 ? 133.525 96.441  102.479 1.00 28.06  ? 697  LEU B N   1 
ATOM   9391  C CA  . LEU B 1 697 ? 133.506 97.377  103.589 1.00 28.06  ? 697  LEU B CA  1 
ATOM   9392  C C   . LEU B 1 697 ? 132.933 98.708  103.126 1.00 28.06  ? 697  LEU B C   1 
ATOM   9393  O O   . LEU B 1 697 ? 133.221 99.168  102.018 1.00 28.06  ? 697  LEU B O   1 
ATOM   9394  C CB  . LEU B 1 697 ? 134.913 97.574  104.159 1.00 28.06  ? 697  LEU B CB  1 
ATOM   9395  C CG  . LEU B 1 697 ? 135.618 96.335  104.718 1.00 28.06  ? 697  LEU B CG  1 
ATOM   9396  C CD1 . LEU B 1 697 ? 136.847 96.729  105.487 1.00 28.06  ? 697  LEU B CD1 1 
ATOM   9397  C CD2 . LEU B 1 697 ? 134.705 95.534  105.612 1.00 28.06  ? 697  LEU B CD2 1 
ATOM   9398  N N   . MET B 1 698 ? 132.113 99.324  103.980 1.00 29.56  ? 698  MET B N   1 
ATOM   9399  C CA  . MET B 1 698 ? 131.540 100.633 103.701 1.00 29.56  ? 698  MET B CA  1 
ATOM   9400  C C   . MET B 1 698 ? 132.342 101.765 104.326 1.00 29.56  ? 698  MET B C   1 
ATOM   9401  O O   . MET B 1 698 ? 131.792 102.834 104.608 1.00 29.56  ? 698  MET B O   1 
ATOM   9402  C CB  . MET B 1 698 ? 130.086 100.684 104.166 1.00 29.56  ? 698  MET B CB  1 
ATOM   9403  C CG  . MET B 1 698 ? 129.221 101.467 103.234 1.00 29.56  ? 698  MET B CG  1 
ATOM   9404  S SD  . MET B 1 698 ? 127.455 101.328 103.429 1.00 29.56  ? 698  MET B SD  1 
ATOM   9405  C CE  . MET B 1 698 ? 127.036 102.573 102.224 1.00 29.56  ? 698  MET B CE  1 
ATOM   9406  N N   . LEU B 1 699 ? 133.636 101.568 104.539 1.00 37.26  ? 699  LEU B N   1 
ATOM   9407  C CA  . LEU B 1 699 ? 134.443 102.559 105.230 1.00 37.26  ? 699  LEU B CA  1 
ATOM   9408  C C   . LEU B 1 699 ? 135.869 102.470 104.688 1.00 37.26  ? 699  LEU B C   1 
ATOM   9409  O O   . LEU B 1 699 ? 136.199 101.583 103.897 1.00 37.26  ? 699  LEU B O   1 
ATOM   9410  C CB  . LEU B 1 699 ? 134.296 102.347 106.749 1.00 37.26  ? 699  LEU B CB  1 
ATOM   9411  C CG  . LEU B 1 699 ? 134.898 103.197 107.880 1.00 37.26  ? 699  LEU B CG  1 
ATOM   9412  C CD1 . LEU B 1 699 ? 133.997 103.165 109.079 1.00 37.26  ? 699  LEU B CD1 1 
ATOM   9413  C CD2 . LEU B 1 699 ? 136.246 102.662 108.305 1.00 37.26  ? 699  LEU B CD2 1 
ATOM   9414  N N   . ARG B 1 700 ? 136.717 103.382 105.140 1.00 42.00  ? 700  ARG B N   1 
ATOM   9415  C CA  . ARG B 1 700 ? 138.111 103.575 104.794 1.00 42.00  ? 700  ARG B CA  1 
ATOM   9416  C C   . ARG B 1 700 ? 138.970 102.503 105.473 1.00 42.00  ? 700  ARG B C   1 
ATOM   9417  O O   . ARG B 1 700 ? 138.477 101.416 105.797 1.00 42.00  ? 700  ARG B O   1 
ATOM   9418  C CB  . ARG B 1 700 ? 138.522 105.001 105.178 1.00 42.00  ? 700  ARG B CB  1 
ATOM   9419  C CG  . ARG B 1 700 ? 137.825 106.082 104.361 1.00 42.00  ? 700  ARG B CG  1 
ATOM   9420  C CD  . ARG B 1 700 ? 137.455 107.290 105.215 1.00 42.00  ? 700  ARG B CD  1 
ATOM   9421  N NE  . ARG B 1 700 ? 136.223 107.076 105.973 1.00 42.00  ? 700  ARG B NE  1 
ATOM   9422  C CZ  . ARG B 1 700 ? 135.008 107.391 105.536 1.00 42.00  ? 700  ARG B CZ  1 
ATOM   9423  N NH1 . ARG B 1 700 ? 133.947 107.157 106.296 1.00 42.00  ? 700  ARG B NH1 1 
ATOM   9424  N NH2 . ARG B 1 700 ? 134.854 107.941 104.339 1.00 42.00  ? 700  ARG B NH2 1 
ATOM   9425  N N   . GLN B 1 701 ? 140.265 102.806 105.651 1.00 48.55  ? 701  GLN B N   1 
ATOM   9426  C CA  . GLN B 1 701 ? 141.393 101.924 105.973 1.00 48.55  ? 701  GLN B CA  1 
ATOM   9427  C C   . GLN B 1 701 ? 141.114 100.768 106.929 1.00 48.55  ? 701  GLN B C   1 
ATOM   9428  O O   . GLN B 1 701 ? 140.355 100.899 107.894 1.00 48.55  ? 701  GLN B O   1 
ATOM   9429  C CB  . GLN B 1 701 ? 142.546 102.763 106.548 1.00 48.55  ? 701  GLN B CB  1 
ATOM   9430  C CG  . GLN B 1 701 ? 142.237 103.484 107.869 1.00 48.55  ? 701  GLN B CG  1 
ATOM   9431  C CD  . GLN B 1 701 ? 143.428 104.234 108.438 1.00 48.55  ? 701  GLN B CD  1 
ATOM   9432  O OE1 . GLN B 1 701 ? 144.523 104.201 107.877 1.00 48.55  ? 701  GLN B OE1 1 
ATOM   9433  N NE2 . GLN B 1 701 ? 143.223 104.901 109.569 1.00 48.55  ? 701  GLN B NE2 1 
ATOM   9434  N N   . LYS B 1 702 ? 141.703 99.611  106.637 1.00 46.20  ? 702  LYS B N   1 
ATOM   9435  C CA  . LYS B 1 702 ? 141.407 98.381  107.361 1.00 46.20  ? 702  LYS B CA  1 
ATOM   9436  C C   . LYS B 1 702 ? 142.177 98.301  108.672 1.00 46.20  ? 702  LYS B C   1 
ATOM   9437  O O   . LYS B 1 702 ? 142.830 97.292  108.950 1.00 46.20  ? 702  LYS B O   1 
ATOM   9438  C CB  . LYS B 1 702 ? 141.749 97.167  106.494 1.00 46.20  ? 702  LYS B CB  1 
ATOM   9439  C CG  . LYS B 1 702 ? 140.608 96.635  105.641 1.00 46.20  ? 702  LYS B CG  1 
ATOM   9440  C CD  . LYS B 1 702 ? 140.289 97.541  104.455 1.00 46.20  ? 702  LYS B CD  1 
ATOM   9441  C CE  . LYS B 1 702 ? 141.510 97.851  103.617 1.00 46.20  ? 702  LYS B CE  1 
ATOM   9442  N NZ  . LYS B 1 702 ? 141.134 98.673  102.438 1.00 46.20  ? 702  LYS B NZ  1 
ATOM   9443  N N   . SER B 1 703 ? 142.097 99.337  109.481 1.00 42.53  ? 703  SER B N   1 
ATOM   9444  C CA  . SER B 1 703 ? 142.779 99.426  110.762 1.00 42.53  ? 703  SER B CA  1 
ATOM   9445  C C   . SER B 1 703 ? 141.837 99.809  111.886 1.00 42.53  ? 703  SER B C   1 
ATOM   9446  O O   . SER B 1 703 ? 141.980 99.298  112.999 1.00 42.53  ? 703  SER B O   1 
ATOM   9447  C CB  . SER B 1 703 ? 143.927 100.442 110.686 1.00 42.53  ? 703  SER B CB  1 
ATOM   9448  O OG  . SER B 1 703 ? 144.257 100.930 111.974 1.00 42.53  ? 703  SER B OG  1 
ATOM   9449  N N   . ILE B 1 704 ? 140.872 100.694 111.622 1.00 41.47  ? 704  ILE B N   1 
ATOM   9450  C CA  . ILE B 1 704 ? 139.899 101.071 112.641 1.00 41.47  ? 704  ILE B CA  1 
ATOM   9451  C C   . ILE B 1 704 ? 138.722 100.120 112.691 1.00 41.47  ? 704  ILE B C   1 
ATOM   9452  O O   . ILE B 1 704 ? 137.867 100.255 113.572 1.00 41.47  ? 704  ILE B O   1 
ATOM   9453  C CB  . ILE B 1 704 ? 139.412 102.513 112.416 1.00 41.47  ? 704  ILE B CB  1 
ATOM   9454  C CG1 . ILE B 1 704 ? 139.011 102.722 110.956 1.00 41.47  ? 704  ILE B CG1 1 
ATOM   9455  C CG2 . ILE B 1 704 ? 140.491 103.501 112.839 1.00 41.47  ? 704  ILE B CG2 1 
ATOM   9456  C CD1 . ILE B 1 704 ? 138.734 104.170 110.596 1.00 41.47  ? 704  ILE B CD1 1 
ATOM   9457  N N   . TYR B 1 705 ? 138.652 99.160  111.770 1.00 38.30  ? 705  TYR B N   1 
ATOM   9458  C CA  . TYR B 1 705 ? 137.659 98.103  111.896 1.00 38.30  ? 705  TYR B CA  1 
ATOM   9459  C C   . TYR B 1 705 ? 138.003 97.173  113.046 1.00 38.30  ? 705  TYR B C   1 
ATOM   9460  O O   . TYR B 1 705 ? 137.121 96.763  113.803 1.00 38.30  ? 705  TYR B O   1 
ATOM   9461  C CB  . TYR B 1 705 ? 137.562 97.319  110.595 1.00 38.30  ? 705  TYR B CB  1 
ATOM   9462  C CG  . TYR B 1 705 ? 136.446 97.779  109.709 1.00 38.30  ? 705  TYR B CG  1 
ATOM   9463  C CD1 . TYR B 1 705 ? 135.163 97.283  109.871 1.00 38.30  ? 705  TYR B CD1 1 
ATOM   9464  C CD2 . TYR B 1 705 ? 136.669 98.713  108.712 1.00 38.30  ? 705  TYR B CD2 1 
ATOM   9465  C CE1 . TYR B 1 705 ? 134.131 97.704  109.059 1.00 38.30  ? 705  TYR B CE1 1 
ATOM   9466  C CE2 . TYR B 1 705 ? 135.647 99.139  107.898 1.00 38.30  ? 705  TYR B CE2 1 
ATOM   9467  C CZ  . TYR B 1 705 ? 134.381 98.634  108.076 1.00 38.30  ? 705  TYR B CZ  1 
ATOM   9468  O OH  . TYR B 1 705 ? 133.360 99.061  107.266 1.00 38.30  ? 705  TYR B OH  1 
ATOM   9469  N N   . TYR B 1 706 ? 139.281 96.840  113.194 1.00 46.38  ? 706  TYR B N   1 
ATOM   9470  C CA  . TYR B 1 706 ? 139.732 95.940  114.242 1.00 46.38  ? 706  TYR B CA  1 
ATOM   9471  C C   . TYR B 1 706 ? 139.794 96.604  115.605 1.00 46.38  ? 706  TYR B C   1 
ATOM   9472  O O   . TYR B 1 706 ? 139.717 95.906  116.622 1.00 46.38  ? 706  TYR B O   1 
ATOM   9473  C CB  . TYR B 1 706 ? 141.117 95.386  113.899 1.00 46.38  ? 706  TYR B CB  1 
ATOM   9474  C CG  . TYR B 1 706 ? 141.177 94.618  112.601 1.00 46.38  ? 706  TYR B CG  1 
ATOM   9475  C CD1 . TYR B 1 706 ? 140.749 93.302  112.534 1.00 46.38  ? 706  TYR B CD1 1 
ATOM   9476  C CD2 . TYR B 1 706 ? 141.658 95.213  111.443 1.00 46.38  ? 706  TYR B CD2 1 
ATOM   9477  C CE1 . TYR B 1 706 ? 140.801 92.598  111.352 1.00 46.38  ? 706  TYR B CE1 1 
ATOM   9478  C CE2 . TYR B 1 706 ? 141.713 94.516  110.254 1.00 46.38  ? 706  TYR B CE2 1 
ATOM   9479  C CZ  . TYR B 1 706 ? 141.285 93.210  110.214 1.00 46.38  ? 706  TYR B CZ  1 
ATOM   9480  O OH  . TYR B 1 706 ? 141.340 92.510  109.030 1.00 46.38  ? 706  TYR B OH  1 
ATOM   9481  N N   . PHE B 1 707 ? 139.952 97.927  115.649 1.00 41.97  ? 707  PHE B N   1 
ATOM   9482  C CA  . PHE B 1 707 ? 139.944 98.637  116.922 1.00 41.97  ? 707  PHE B CA  1 
ATOM   9483  C C   . PHE B 1 707 ? 138.550 98.649  117.533 1.00 41.97  ? 707  PHE B C   1 
ATOM   9484  O O   . PHE B 1 707 ? 138.403 98.646  118.758 1.00 41.97  ? 707  PHE B O   1 
ATOM   9485  C CB  . PHE B 1 707 ? 140.461 100.062 116.730 1.00 41.97  ? 707  PHE B CB  1 
ATOM   9486  C CG  . PHE B 1 707 ? 140.488 100.868 117.990 1.00 41.97  ? 707  PHE B CG  1 
ATOM   9487  C CD1 . PHE B 1 707 ? 139.840 102.088 118.061 1.00 41.97  ? 707  PHE B CD1 1 
ATOM   9488  C CD2 . PHE B 1 707 ? 141.156 100.400 119.108 1.00 41.97  ? 707  PHE B CD2 1 
ATOM   9489  C CE1 . PHE B 1 707 ? 139.859 102.832 119.225 1.00 41.97  ? 707  PHE B CE1 1 
ATOM   9490  C CE2 . PHE B 1 707 ? 141.180 101.138 120.277 1.00 41.97  ? 707  PHE B CE2 1 
ATOM   9491  C CZ  . PHE B 1 707 ? 140.531 102.356 120.334 1.00 41.97  ? 707  PHE B CZ  1 
ATOM   9492  N N   . SER B 1 708 ? 137.516 98.642  116.696 1.00 32.13  ? 708  SER B N   1 
ATOM   9493  C CA  . SER B 1 708 ? 136.162 98.563  117.217 1.00 32.13  ? 708  SER B CA  1 
ATOM   9494  C C   . SER B 1 708 ? 135.761 97.140  117.570 1.00 32.13  ? 708  SER B C   1 
ATOM   9495  O O   . SER B 1 708 ? 134.696 96.944  118.154 1.00 32.13  ? 708  SER B O   1 
ATOM   9496  C CB  . SER B 1 708 ? 135.175 99.146  116.211 1.00 32.13  ? 708  SER B CB  1 
ATOM   9497  O OG  . SER B 1 708 ? 133.866 98.694  116.485 1.00 32.13  ? 708  SER B OG  1 
ATOM   9498  N N   . MET B 1 709 ? 136.578 96.146  117.233 1.00 35.78  ? 709  MET B N   1 
ATOM   9499  C CA  . MET B 1 709 ? 136.281 94.773  117.617 1.00 35.78  ? 709  MET B CA  1 
ATOM   9500  C C   . MET B 1 709 ? 136.842 94.403  118.980 1.00 35.78  ? 709  MET B C   1 
ATOM   9501  O O   . MET B 1 709 ? 136.399 93.410  119.564 1.00 35.78  ? 709  MET B O   1 
ATOM   9502  C CB  . MET B 1 709 ? 136.817 93.801  116.568 1.00 35.78  ? 709  MET B CB  1 
ATOM   9503  C CG  . MET B 1 709 ? 136.194 93.989  115.209 1.00 35.78  ? 709  MET B CG  1 
ATOM   9504  S SD  . MET B 1 709 ? 136.687 92.752  114.008 1.00 35.78  ? 709  MET B SD  1 
ATOM   9505  C CE  . MET B 1 709 ? 135.373 91.559  114.203 1.00 35.78  ? 709  MET B CE  1 
ATOM   9506  N N   . VAL B 1 710 ? 137.801 95.164  119.496 1.00 33.18  ? 710  VAL B N   1 
ATOM   9507  C CA  . VAL B 1 710 ? 138.366 94.889  120.810 1.00 33.18  ? 710  VAL B CA  1 
ATOM   9508  C C   . VAL B 1 710 ? 137.625 95.757  121.820 1.00 33.18  ? 710  VAL B C   1 
ATOM   9509  O O   . VAL B 1 710 ? 137.590 95.452  123.017 1.00 33.18  ? 710  VAL B O   1 
ATOM   9510  C CB  . VAL B 1 710 ? 139.894 95.123  120.814 1.00 33.18  ? 710  VAL B CB  1 
ATOM   9511  C CG1 . VAL B 1 710 ? 140.242 96.584  120.586 1.00 33.18  ? 710  VAL B CG1 1 
ATOM   9512  C CG2 . VAL B 1 710 ? 140.557 94.570  122.077 1.00 33.18  ? 710  VAL B CG2 1 
ATOM   9513  N N   . LEU B 1 711 ? 136.974 96.816  121.337 1.00 27.97  ? 711  LEU B N   1 
ATOM   9514  C CA  . LEU B 1 711 ? 136.201 97.684  122.215 1.00 27.97  ? 711  LEU B CA  1 
ATOM   9515  C C   . LEU B 1 711 ? 134.793 97.183  122.483 1.00 27.97  ? 711  LEU B C   1 
ATOM   9516  O O   . LEU B 1 711 ? 134.078 97.812  123.264 1.00 27.97  ? 711  LEU B O   1 
ATOM   9517  C CB  . LEU B 1 711 ? 136.114 99.095  121.650 1.00 27.97  ? 711  LEU B CB  1 
ATOM   9518  C CG  . LEU B 1 711 ? 137.357 99.959  121.753 1.00 27.97  ? 711  LEU B CG  1 
ATOM   9519  C CD1 . LEU B 1 711 ? 137.096 101.279 121.065 1.00 27.97  ? 711  LEU B CD1 1 
ATOM   9520  C CD2 . LEU B 1 711 ? 137.701 100.171 123.212 1.00 27.97  ? 711  LEU B CD2 1 
ATOM   9521  N N   . ASN B 1 712 ? 134.355 96.111  121.848 1.00 21.61  ? 712  ASN B N   1 
ATOM   9522  C CA  . ASN B 1 712 ? 133.115 95.489  122.271 1.00 21.61  ? 712  ASN B CA  1 
ATOM   9523  C C   . ASN B 1 712 ? 133.348 94.359  123.261 1.00 21.61  ? 712  ASN B C   1 
ATOM   9524  O O   . ASN B 1 712 ? 132.381 93.746  123.722 1.00 21.61  ? 712  ASN B O   1 
ATOM   9525  C CB  . ASN B 1 712 ? 132.343 94.965  121.069 1.00 21.61  ? 712  ASN B CB  1 
ATOM   9526  C CG  . ASN B 1 712 ? 130.861 95.035  121.274 1.00 21.61  ? 712  ASN B CG  1 
ATOM   9527  O OD1 . ASN B 1 712 ? 130.312 96.103  121.513 1.00 21.61  ? 712  ASN B OD1 1 
ATOM   9528  N ND2 . ASN B 1 712 ? 130.202 93.892  121.210 1.00 21.61  ? 712  ASN B ND2 1 
ATOM   9529  N N   . LEU B 1 713 ? 134.607 94.080  123.602 1.00 29.64  ? 713  LEU B N   1 
ATOM   9530  C CA  . LEU B 1 713 ? 134.957 93.059  124.577 1.00 29.64  ? 713  LEU B CA  1 
ATOM   9531  C C   . LEU B 1 713 ? 135.568 93.643  125.838 1.00 29.64  ? 713  LEU B C   1 
ATOM   9532  O O   . LEU B 1 713 ? 135.291 93.139  126.930 1.00 29.64  ? 713  LEU B O   1 
ATOM   9533  C CB  . LEU B 1 713 ? 135.935 92.053  123.952 1.00 29.64  ? 713  LEU B CB  1 
ATOM   9534  C CG  . LEU B 1 713 ? 135.989 90.583  124.387 1.00 29.64  ? 713  LEU B CG  1 
ATOM   9535  C CD1 . LEU B 1 713 ? 136.796 89.812  123.362 1.00 29.64  ? 713  LEU B CD1 1 
ATOM   9536  C CD2 . LEU B 1 713 ? 136.573 90.339  125.776 1.00 29.64  ? 713  LEU B CD2 1 
ATOM   9537  N N   . VAL B 1 714 ? 136.406 94.664  125.707 1.00 27.91  ? 714  VAL B N   1 
ATOM   9538  C CA  . VAL B 1 714 ? 136.831 95.468  126.842 1.00 27.91  ? 714  VAL B CA  1 
ATOM   9539  C C   . VAL B 1 714 ? 135.639 96.122  127.516 1.00 27.91  ? 714  VAL B C   1 
ATOM   9540  O O   . VAL B 1 714 ? 135.500 96.068  128.739 1.00 27.91  ? 714  VAL B O   1 
ATOM   9541  C CB  . VAL B 1 714 ? 137.866 96.518  126.379 1.00 27.91  ? 714  VAL B CB  1 
ATOM   9542  C CG1 . VAL B 1 714 ? 138.170 97.502  127.487 1.00 27.91  ? 714  VAL B CG1 1 
ATOM   9543  C CG2 . VAL B 1 714 ? 139.138 95.841  125.919 1.00 27.91  ? 714  VAL B CG2 1 
ATOM   9544  N N   . LEU B 1 715 ? 134.742 96.710  126.721 1.00 22.68  ? 715  LEU B N   1 
ATOM   9545  C CA  . LEU B 1 715 ? 133.600 97.430  127.263 1.00 22.68  ? 715  LEU B CA  1 
ATOM   9546  C C   . LEU B 1 715 ? 132.414 96.533  127.568 1.00 22.68  ? 715  LEU B C   1 
ATOM   9547  O O   . LEU B 1 715 ? 131.341 97.054  127.876 1.00 22.68  ? 715  LEU B O   1 
ATOM   9548  C CB  . LEU B 1 715 ? 133.153 98.534  126.309 1.00 22.68  ? 715  LEU B CB  1 
ATOM   9549  C CG  . LEU B 1 715 ? 134.025 99.784  126.243 1.00 22.68  ? 715  LEU B CG  1 
ATOM   9550  C CD1 . LEU B 1 715 ? 133.665 100.648 125.051 1.00 22.68  ? 715  LEU B CD1 1 
ATOM   9551  C CD2 . LEU B 1 715 ? 133.882 100.566 127.521 1.00 22.68  ? 715  LEU B CD2 1 
ATOM   9552  N N   . ARG B 1 716 ? 132.552 95.217  127.479 1.00 24.15  ? 716  ARG B N   1 
ATOM   9553  C CA  . ARG B 1 716 ? 131.489 94.409  128.050 1.00 24.15  ? 716  ARG B CA  1 
ATOM   9554  C C   . ARG B 1 716 ? 131.914 93.785  129.383 1.00 24.15  ? 716  ARG B C   1 
ATOM   9555  O O   . ARG B 1 716 ? 131.314 92.808  129.838 1.00 24.15  ? 716  ARG B O   1 
ATOM   9556  C CB  . ARG B 1 716 ? 131.005 93.379  127.025 1.00 24.15  ? 716  ARG B CB  1 
ATOM   9557  C CG  . ARG B 1 716 ? 129.542 93.022  127.250 1.00 24.15  ? 716  ARG B CG  1 
ATOM   9558  C CD  . ARG B 1 716 ? 128.964 92.015  126.311 1.00 24.15  ? 716  ARG B CD  1 
ATOM   9559  N NE  . ARG B 1 716 ? 128.733 92.520  124.970 1.00 24.15  ? 716  ARG B NE  1 
ATOM   9560  C CZ  . ARG B 1 716 ? 127.588 93.056  124.580 1.00 24.15  ? 716  ARG B CZ  1 
ATOM   9561  N NH1 . ARG B 1 716 ? 126.577 93.145  125.422 1.00 24.15  ? 716  ARG B NH1 1 
ATOM   9562  N NH2 . ARG B 1 716 ? 127.446 93.480  123.341 1.00 24.15  ? 716  ARG B NH2 1 
ATOM   9563  N N   . LEU B 1 717 ? 132.974 94.308  129.998 1.00 26.63  ? 717  LEU B N   1 
ATOM   9564  C CA  . LEU B 1 717 ? 133.180 94.175  131.433 1.00 26.63  ? 717  LEU B CA  1 
ATOM   9565  C C   . LEU B 1 717 ? 132.515 95.303  132.198 1.00 26.63  ? 717  LEU B C   1 
ATOM   9566  O O   . LEU B 1 717 ? 132.252 95.153  133.395 1.00 26.63  ? 717  LEU B O   1 
ATOM   9567  C CB  . LEU B 1 717 ? 134.672 94.155  131.773 1.00 26.63  ? 717  LEU B CB  1 
ATOM   9568  C CG  . LEU B 1 717 ? 135.422 92.823  131.745 1.00 26.63  ? 717  LEU B CG  1 
ATOM   9569  C CD1 . LEU B 1 717 ? 136.925 93.066  131.672 1.00 26.63  ? 717  LEU B CD1 1 
ATOM   9570  C CD2 . LEU B 1 717 ? 135.064 91.984  132.965 1.00 26.63  ? 717  LEU B CD2 1 
ATOM   9571  N N   . ALA B 1 718 ? 132.224 96.417  131.524 1.00 26.30  ? 718  ALA B N   1 
ATOM   9572  C CA  . ALA B 1 718 ? 131.356 97.432  132.102 1.00 26.30  ? 718  ALA B CA  1 
ATOM   9573  C C   . ALA B 1 718 ? 129.925 96.919  132.208 1.00 26.30  ? 718  ALA B C   1 
ATOM   9574  O O   . ALA B 1 718 ? 129.306 96.998  133.274 1.00 26.30  ? 718  ALA B O   1 
ATOM   9575  C CB  . ALA B 1 718 ? 131.422 98.701  131.264 1.00 26.30  ? 718  ALA B CB  1 
ATOM   9576  N N   . TRP B 1 719 ? 129.389 96.385  131.114 1.00 21.66  ? 719  TRP B N   1 
ATOM   9577  C CA  . TRP B 1 719 ? 128.260 95.468  131.176 1.00 21.66  ? 719  TRP B CA  1 
ATOM   9578  C C   . TRP B 1 719 ? 128.670 94.234  131.978 1.00 21.66  ? 719  TRP B C   1 
ATOM   9579  O O   . TRP B 1 719 ? 129.848 93.879  132.029 1.00 21.66  ? 719  TRP B O   1 
ATOM   9580  C CB  . TRP B 1 719 ? 127.829 95.079  129.763 1.00 21.66  ? 719  TRP B CB  1 
ATOM   9581  C CG  . TRP B 1 719 ? 126.482 94.458  129.629 1.00 21.66  ? 719  TRP B CG  1 
ATOM   9582  C CD1 . TRP B 1 719 ? 125.283 95.100  129.603 1.00 21.66  ? 719  TRP B CD1 1 
ATOM   9583  C CD2 . TRP B 1 719 ? 126.195 93.069  129.469 1.00 21.66  ? 719  TRP B CD2 1 
ATOM   9584  N NE1 . TRP B 1 719 ? 124.264 94.196  129.443 1.00 21.66  ? 719  TRP B NE1 1 
ATOM   9585  C CE2 . TRP B 1 719 ? 124.801 92.940  129.364 1.00 21.66  ? 719  TRP B CE2 1 
ATOM   9586  C CE3 . TRP B 1 719 ? 126.980 91.919  129.417 1.00 21.66  ? 719  TRP B CE3 1 
ATOM   9587  C CZ2 . TRP B 1 719 ? 124.181 91.710  129.212 1.00 21.66  ? 719  TRP B CZ2 1 
ATOM   9588  C CZ3 . TRP B 1 719 ? 126.363 90.706  129.260 1.00 21.66  ? 719  TRP B CZ3 1 
ATOM   9589  C CH2 . TRP B 1 719 ? 124.981 90.608  129.162 1.00 21.66  ? 719  TRP B CH2 1 
ATOM   9590  N N   . LEU B 1 720 ? 127.689 93.626  132.662 1.00 28.43  ? 720  LEU B N   1 
ATOM   9591  C CA  . LEU B 1 720 ? 127.822 92.561  133.671 1.00 28.43  ? 720  LEU B CA  1 
ATOM   9592  C C   . LEU B 1 720 ? 128.491 93.055  134.956 1.00 28.43  ? 720  LEU B C   1 
ATOM   9593  O O   . LEU B 1 720 ? 128.600 92.313  135.935 1.00 28.43  ? 720  LEU B O   1 
ATOM   9594  C CB  . LEU B 1 720 ? 128.548 91.318  133.124 1.00 28.43  ? 720  LEU B CB  1 
ATOM   9595  C CG  . LEU B 1 720 ? 128.394 89.946  133.778 1.00 28.43  ? 720  LEU B CG  1 
ATOM   9596  C CD1 . LEU B 1 720 ? 127.113 89.274  133.332 1.00 28.43  ? 720  LEU B CD1 1 
ATOM   9597  C CD2 . LEU B 1 720 ? 129.613 89.102  133.477 1.00 28.43  ? 720  LEU B CD2 1 
ATOM   9598  N N   . GLN B 1 721 ? 128.909 94.310  135.003 1.00 29.58  ? 721  GLN B N   1 
ATOM   9599  C CA  . GLN B 1 721 ? 129.226 94.877  136.296 1.00 29.58  ? 721  GLN B CA  1 
ATOM   9600  C C   . GLN B 1 721 ? 128.057 95.762  136.667 1.00 29.58  ? 721  GLN B C   1 
ATOM   9601  O O   . GLN B 1 721 ? 127.648 95.811  137.827 1.00 29.58  ? 721  GLN B O   1 
ATOM   9602  C CB  . GLN B 1 721 ? 130.538 95.661  136.265 1.00 29.58  ? 721  GLN B CB  1 
ATOM   9603  C CG  . GLN B 1 721 ? 130.769 96.628  137.439 1.00 29.58  ? 721  GLN B CG  1 
ATOM   9604  C CD  . GLN B 1 721 ? 130.636 96.018  138.840 1.00 29.58  ? 721  GLN B CD  1 
ATOM   9605  O OE1 . GLN B 1 721 ? 130.868 94.827  139.058 1.00 29.58  ? 721  GLN B OE1 1 
ATOM   9606  N NE2 . GLN B 1 721 ? 130.253 96.852  139.798 1.00 29.58  ? 721  GLN B NE2 1 
ATOM   9607  N N   . THR B 1 722 ? 127.447 96.389  135.671 1.00 29.45  ? 722  THR B N   1 
ATOM   9608  C CA  . THR B 1 722 ? 126.406 97.356  135.966 1.00 29.45  ? 722  THR B CA  1 
ATOM   9609  C C   . THR B 1 722 ? 125.047 96.678  136.032 1.00 29.45  ? 722  THR B C   1 
ATOM   9610  O O   . THR B 1 722 ? 124.061 97.304  136.426 1.00 29.45  ? 722  THR B O   1 
ATOM   9611  C CB  . THR B 1 722 ? 126.412 98.477  134.928 1.00 29.45  ? 722  THR B CB  1 
ATOM   9612  O OG1 . THR B 1 722 ? 126.349 97.923  133.612 1.00 29.45  ? 722  THR B OG1 1 
ATOM   9613  C CG2 . THR B 1 722 ? 127.677 99.286  135.056 1.00 29.45  ? 722  THR B CG2 1 
ATOM   9614  N N   . VAL B 1 723 ? 124.978 95.402  135.670 1.00 30.44  ? 723  VAL B N   1 
ATOM   9615  C CA  . VAL B 1 723 ? 123.731 94.660  135.733 1.00 30.44  ? 723  VAL B CA  1 
ATOM   9616  C C   . VAL B 1 723 ? 123.811 93.504  136.734 1.00 30.44  ? 723  VAL B C   1 
ATOM   9617  O O   . VAL B 1 723 ? 122.906 92.677  136.794 1.00 30.44  ? 723  VAL B O   1 
ATOM   9618  C CB  . VAL B 1 723 ? 123.289 94.169  134.349 1.00 30.44  ? 723  VAL B CB  1 
ATOM   9619  C CG1 . VAL B 1 723 ? 123.140 95.331  133.396 1.00 30.44  ? 723  VAL B CG1 1 
ATOM   9620  C CG2 . VAL B 1 723 ? 124.213 93.109  133.811 1.00 30.44  ? 723  VAL B CG2 1 
ATOM   9621  N N   . LEU B 1 724 ? 124.886 93.429  137.519 1.00 37.36  ? 724  LEU B N   1 
ATOM   9622  C CA  . LEU B 1 724 ? 124.895 92.554  138.684 1.00 37.36  ? 724  LEU B CA  1 
ATOM   9623  C C   . LEU B 1 724 ? 125.112 93.331  139.971 1.00 37.36  ? 724  LEU B C   1 
ATOM   9624  O O   . LEU B 1 724 ? 124.999 92.748  141.054 1.00 37.36  ? 724  LEU B O   1 
ATOM   9625  C CB  . LEU B 1 724 ? 125.966 91.468  138.579 1.00 37.36  ? 724  LEU B CB  1 
ATOM   9626  C CG  . LEU B 1 724 ? 126.063 90.585  137.341 1.00 37.36  ? 724  LEU B CG  1 
ATOM   9627  C CD1 . LEU B 1 724 ? 127.302 89.712  137.432 1.00 37.36  ? 724  LEU B CD1 1 
ATOM   9628  C CD2 . LEU B 1 724 ? 124.824 89.736  137.191 1.00 37.36  ? 724  LEU B CD2 1 
ATOM   9629  N N   . HIS B 1 725 ? 125.414 94.620  139.883 1.00 44.27  ? 725  HIS B N   1 
ATOM   9630  C CA  . HIS B 1 725 ? 125.776 95.467  141.011 1.00 44.27  ? 725  HIS B CA  1 
ATOM   9631  C C   . HIS B 1 725 ? 124.912 96.707  141.018 1.00 44.27  ? 725  HIS B C   1 
ATOM   9632  O O   . HIS B 1 725 ? 125.414 97.828  140.899 1.00 44.27  ? 725  HIS B O   1 
ATOM   9633  C CB  . HIS B 1 725 ? 127.246 95.875  141.016 1.00 44.27  ? 725  HIS B CB  1 
ATOM   9634  C CG  . HIS B 1 725 ? 128.153 94.875  141.659 1.00 44.27  ? 725  HIS B CG  1 
ATOM   9635  N ND1 . HIS B 1 725 ? 128.901 93.973  140.933 1.00 44.27  ? 725  HIS B ND1 1 
ATOM   9636  C CD2 . HIS B 1 725 ? 128.424 94.626  142.962 1.00 44.27  ? 725  HIS B CD2 1 
ATOM   9637  C CE1 . HIS B 1 725 ? 129.600 93.217  141.761 1.00 44.27  ? 725  HIS B CE1 1 
ATOM   9638  N NE2 . HIS B 1 725 ? 129.327 93.592  142.998 1.00 44.27  ? 725  HIS B NE2 1 
ATOM   9639  N N   . SER B 1 726 ? 123.589 96.492  141.042 1.00 45.89  ? 726  SER B N   1 
ATOM   9640  C CA  . SER B 1 726 ? 122.563 97.533  141.091 1.00 45.89  ? 726  SER B CA  1 
ATOM   9641  C C   . SER B 1 726 ? 122.852 98.596  142.141 1.00 45.89  ? 726  SER B C   1 
ATOM   9642  O O   . SER B 1 726 ? 122.878 98.308  143.340 1.00 45.89  ? 726  SER B O   1 
ATOM   9643  C CB  . SER B 1 726 ? 121.195 96.913  141.365 1.00 45.89  ? 726  SER B CB  1 
ATOM   9644  O OG  . SER B 1 726 ? 120.312 97.869  141.924 1.00 45.89  ? 726  SER B OG  1 
ATOM   9645  N N   . SER B 1 727 ? 123.062 99.828  141.674 1.00 50.97  ? 727  SER B N   1 
ATOM   9646  C CA  . SER B 1 727 ? 123.783 100.817 142.464 1.00 50.97  ? 727  SER B CA  1 
ATOM   9647  C C   . SER B 1 727 ? 122.941 101.348 143.612 1.00 50.97  ? 727  SER B C   1 
ATOM   9648  O O   . SER B 1 727 ? 123.424 101.426 144.748 1.00 50.97  ? 727  SER B O   1 
ATOM   9649  C CB  . SER B 1 727 ? 124.251 101.959 141.570 1.00 50.97  ? 727  SER B CB  1 
ATOM   9650  O OG  . SER B 1 727 ? 124.728 103.034 142.353 1.00 50.97  ? 727  SER B OG  1 
ATOM   9651  N N   . PHE B 1 728 ? 121.689 101.721 143.353 1.00 49.12  ? 728  PHE B N   1 
ATOM   9652  C CA  . PHE B 1 728 ? 120.874 102.147 144.481 1.00 49.12  ? 728  PHE B CA  1 
ATOM   9653  C C   . PHE B 1 728 ? 120.030 101.000 145.018 1.00 49.12  ? 728  PHE B C   1 
ATOM   9654  O O   . PHE B 1 728 ? 118.797 101.067 145.022 1.00 49.12  ? 728  PHE B O   1 
ATOM   9655  C CB  . PHE B 1 728 ? 119.981 103.336 144.138 1.00 49.12  ? 728  PHE B CB  1 
ATOM   9656  C CG  . PHE B 1 728 ? 119.726 104.220 145.321 1.00 49.12  ? 728  PHE B CG  1 
ATOM   9657  C CD1 . PHE B 1 728 ? 120.654 105.181 145.691 1.00 49.12  ? 728  PHE B CD1 1 
ATOM   9658  C CD2 . PHE B 1 728 ? 118.609 104.033 146.118 1.00 49.12  ? 728  PHE B CD2 1 
ATOM   9659  C CE1 . PHE B 1 728 ? 120.443 105.974 146.798 1.00 49.12  ? 728  PHE B CE1 1 
ATOM   9660  C CE2 . PHE B 1 728 ? 118.401 104.817 147.229 1.00 49.12  ? 728  PHE B CE2 1 
ATOM   9661  C CZ  . PHE B 1 728 ? 119.312 105.791 147.566 1.00 49.12  ? 728  PHE B CZ  1 
ATOM   9662  N N   . GLU B 1 729 ? 120.691 99.926  145.436 1.00 57.31  ? 729  GLU B N   1 
ATOM   9663  C CA  . GLU B 1 729 ? 120.056 98.900  146.247 1.00 57.31  ? 729  GLU B CA  1 
ATOM   9664  C C   . GLU B 1 729 ? 121.028 98.502  147.352 1.00 57.31  ? 729  GLU B C   1 
ATOM   9665  O O   . GLU B 1 729 ? 120.622 98.102  148.448 1.00 57.31  ? 729  GLU B O   1 
ATOM   9666  C CB  . GLU B 1 729 ? 119.651 97.707  145.373 1.00 57.31  ? 729  GLU B CB  1 
ATOM   9667  C CG  . GLU B 1 729 ? 118.999 96.547  146.110 1.00 57.31  ? 729  GLU B CG  1 
ATOM   9668  C CD  . GLU B 1 729 ? 119.176 95.228  145.388 1.00 57.31  ? 729  GLU B CD  1 
ATOM   9669  O OE1 . GLU B 1 729 ? 120.181 94.534  145.650 1.00 57.31  ? 729  GLU B OE1 1 
ATOM   9670  O OE2 . GLU B 1 729 ? 118.309 94.885  144.558 1.00 57.31  ? 729  GLU B OE2 1 
ATOM   9671  N N   . HIS B 1 730 ? 122.318 98.660  147.081 1.00 58.63  ? 730  HIS B N   1 
ATOM   9672  C CA  . HIS B 1 730 ? 123.385 98.173  147.948 1.00 58.63  ? 730  HIS B CA  1 
ATOM   9673  C C   . HIS B 1 730 ? 124.574 99.119  147.808 1.00 58.63  ? 730  HIS B C   1 
ATOM   9674  O O   . HIS B 1 730 ? 124.404 100.294 147.465 1.00 58.63  ? 730  HIS B O   1 
ATOM   9675  C CB  . HIS B 1 730 ? 123.724 96.705  147.661 1.00 58.63  ? 730  HIS B CB  1 
ATOM   9676  C CG  . HIS B 1 730 ? 123.992 96.400  146.222 1.00 58.63  ? 730  HIS B CG  1 
ATOM   9677  N ND1 . HIS B 1 730 ? 123.217 95.522  145.495 1.00 58.63  ? 730  HIS B ND1 1 
ATOM   9678  C CD2 . HIS B 1 730 ? 124.966 96.825  145.384 1.00 58.63  ? 730  HIS B CD2 1 
ATOM   9679  C CE1 . HIS B 1 730 ? 123.692 95.431  144.266 1.00 58.63  ? 730  HIS B CE1 1 
ATOM   9680  N NE2 . HIS B 1 730 ? 124.753 96.213  144.173 1.00 58.63  ? 730  HIS B NE2 1 
ATOM   9681  N N   . VAL B 1 731 ? 125.779 98.578  148.044 1.00 53.81  ? 731  VAL B N   1 
ATOM   9682  C CA  . VAL B 1 731 ? 127.007 99.198  148.559 1.00 53.81  ? 731  VAL B CA  1 
ATOM   9683  C C   . VAL B 1 731 ? 127.295 100.621 148.069 1.00 53.81  ? 731  VAL B C   1 
ATOM   9684  O O   . VAL B 1 731 ? 127.146 100.942 146.883 1.00 53.81  ? 731  VAL B O   1 
ATOM   9685  C CB  . VAL B 1 731 ? 128.189 98.243  148.253 1.00 53.81  ? 731  VAL B CB  1 
ATOM   9686  C CG1 . VAL B 1 731 ? 128.274 97.908  146.759 1.00 53.81  ? 731  VAL B CG1 1 
ATOM   9687  C CG2 . VAL B 1 731 ? 129.528 98.760  148.786 1.00 53.81  ? 731  VAL B CG2 1 
ATOM   9688  N N   . ASP B 1 732 ? 127.703 101.484 149.010 1.00 51.32  ? 732  ASP B N   1 
ATOM   9689  C CA  . ASP B 1 732 ? 127.698 102.934 148.845 1.00 51.32  ? 732  ASP B CA  1 
ATOM   9690  C C   . ASP B 1 732 ? 128.859 103.481 148.019 1.00 51.32  ? 732  ASP B C   1 
ATOM   9691  O O   . ASP B 1 732 ? 129.158 104.676 148.113 1.00 51.32  ? 732  ASP B O   1 
ATOM   9692  C CB  . ASP B 1 732 ? 127.709 103.593 150.226 1.00 51.32  ? 732  ASP B CB  1 
ATOM   9693  C CG  . ASP B 1 732 ? 129.035 103.408 150.949 1.00 51.32  ? 732  ASP B CG  1 
ATOM   9694  O OD1 . ASP B 1 732 ? 129.586 102.288 150.908 1.00 51.32  ? 732  ASP B OD1 1 
ATOM   9695  O OD2 . ASP B 1 732 ? 129.525 104.384 151.556 1.00 51.32  ? 732  ASP B OD2 1 
ATOM   9696  N N   . TYR B 1 733 ? 129.546 102.649 147.240 1.00 48.38  ? 733  TYR B N   1 
ATOM   9697  C CA  . TYR B 1 733 ? 130.538 103.155 146.293 1.00 48.38  ? 733  TYR B CA  1 
ATOM   9698  C C   . TYR B 1 733 ? 129.780 103.621 145.051 1.00 48.38  ? 733  TYR B C   1 
ATOM   9699  O O   . TYR B 1 733 ? 129.288 102.833 144.241 1.00 48.38  ? 733  TYR B O   1 
ATOM   9700  C CB  . TYR B 1 733 ? 131.575 102.088 145.939 1.00 30.00  ? 733  TYR B CB  1 
ATOM   9701  C CG  . TYR B 1 733 ? 132.572 102.526 144.889 1.00 30.00  ? 733  TYR B CG  1 
ATOM   9702  C CD1 . TYR B 1 733 ? 133.622 103.376 145.214 1.00 30.00  ? 733  TYR B CD1 1 
ATOM   9703  C CD2 . TYR B 1 733 ? 132.462 102.088 143.577 1.00 30.00  ? 733  TYR B CD2 1 
ATOM   9704  C CE1 . TYR B 1 733 ? 134.535 103.778 144.258 1.00 30.00  ? 733  TYR B CE1 1 
ATOM   9705  C CE2 . TYR B 1 733 ? 133.372 102.486 142.614 1.00 30.00  ? 733  TYR B CE2 1 
ATOM   9706  C CZ  . TYR B 1 733 ? 134.405 103.330 142.960 1.00 30.00  ? 733  TYR B CZ  1 
ATOM   9707  O OH  . TYR B 1 733 ? 135.313 103.730 142.005 1.00 30.00  ? 733  TYR B OH  1 
ATOM   9708  N N   . ARG B 1 734 ? 129.673 104.942 144.912 1.00 42.32  ? 734  ARG B N   1 
ATOM   9709  C CA  . ARG B 1 734 ? 128.693 105.550 144.019 1.00 42.32  ? 734  ARG B CA  1 
ATOM   9710  C C   . ARG B 1 734 ? 129.252 105.963 142.664 1.00 42.32  ? 734  ARG B C   1 
ATOM   9711  O O   . ARG B 1 734 ? 128.548 105.882 141.653 1.00 42.32  ? 734  ARG B O   1 
ATOM   9712  C CB  . ARG B 1 734 ? 128.076 106.776 144.689 1.00 42.32  ? 734  ARG B CB  1 
ATOM   9713  C CG  . ARG B 1 734 ? 127.451 106.501 146.034 1.00 42.32  ? 734  ARG B CG  1 
ATOM   9714  C CD  . ARG B 1 734 ? 126.277 105.575 145.891 1.00 42.32  ? 734  ARG B CD  1 
ATOM   9715  N NE  . ARG B 1 734 ? 125.305 106.124 144.959 1.00 42.32  ? 734  ARG B NE  1 
ATOM   9716  C CZ  . ARG B 1 734 ? 124.391 105.401 144.331 1.00 42.32  ? 734  ARG B CZ  1 
ATOM   9717  N NH1 . ARG B 1 734 ? 123.545 105.981 143.497 1.00 42.32  ? 734  ARG B NH1 1 
ATOM   9718  N NH2 . ARG B 1 734 ? 124.332 104.094 144.531 1.00 42.32  ? 734  ARG B NH2 1 
ATOM   9719  N N   . VAL B 1 735 ? 130.495 106.439 142.627 1.00 39.31  ? 735  VAL B N   1 
ATOM   9720  C CA  . VAL B 1 735 ? 131.021 107.072 141.422 1.00 39.31  ? 735  VAL B CA  1 
ATOM   9721  C C   . VAL B 1 735 ? 131.463 105.997 140.430 1.00 39.31  ? 735  VAL B C   1 
ATOM   9722  O O   . VAL B 1 735 ? 131.686 106.278 139.247 1.00 39.31  ? 735  VAL B O   1 
ATOM   9723  C CB  . VAL B 1 735 ? 132.166 108.046 141.767 1.00 39.31  ? 735  VAL B CB  1 
ATOM   9724  C CG1 . VAL B 1 735 ? 133.459 107.299 142.057 1.00 39.31  ? 735  VAL B CG1 1 
ATOM   9725  C CG2 . VAL B 1 735 ? 132.341 109.123 140.695 1.00 39.31  ? 735  VAL B CG2 1 
ATOM   9726  N N   . THR B 1 736 ? 131.577 104.752 140.888 1.00 35.00  ? 736  THR B N   1 
ATOM   9727  C CA  . THR B 1 736 ? 131.778 103.647 139.959 1.00 35.00  ? 736  THR B CA  1 
ATOM   9728  C C   . THR B 1 736 ? 130.469 103.306 139.260 1.00 35.00  ? 736  THR B C   1 
ATOM   9729  O O   . THR B 1 736 ? 130.469 102.753 138.158 1.00 35.00  ? 736  THR B O   1 
ATOM   9730  C CB  . THR B 1 736 ? 132.340 102.419 140.679 1.00 35.00  ? 736  THR B CB  1 
ATOM   9731  O OG1 . THR B 1 736 ? 132.302 101.289 139.802 1.00 35.00  ? 736  THR B OG1 1 
ATOM   9732  C CG2 . THR B 1 736 ? 131.546 102.110 141.933 1.00 35.00  ? 736  THR B CG2 1 
ATOM   9733  N N   . GLY B 1 737 ? 129.348 103.638 139.891 1.00 30.12  ? 737  GLY B N   1 
ATOM   9734  C CA  . GLY B 1 737 ? 128.046 103.354 139.328 1.00 30.12  ? 737  GLY B CA  1 
ATOM   9735  C C   . GLY B 1 737 ? 127.610 104.374 138.303 1.00 30.12  ? 737  GLY B C   1 
ATOM   9736  O O   . GLY B 1 737 ? 126.562 104.216 137.679 1.00 30.12  ? 737  GLY B O   1 
ATOM   9737  N N   . LEU B 1 738 ? 128.387 105.443 138.145 1.00 26.02  ? 738  LEU B N   1 
ATOM   9738  C CA  . LEU B 1 738 ? 128.150 106.436 137.111 1.00 26.02  ? 738  LEU B CA  1 
ATOM   9739  C C   . LEU B 1 738 ? 129.350 106.613 136.199 1.00 26.02  ? 738  LEU B C   1 
ATOM   9740  O O   . LEU B 1 738 ? 129.313 107.450 135.297 1.00 26.02  ? 738  LEU B O   1 
ATOM   9741  C CB  . LEU B 1 738 ? 127.766 107.780 137.736 1.00 26.02  ? 738  LEU B CB  1 
ATOM   9742  C CG  . LEU B 1 738 ? 126.837 108.693 136.940 1.00 26.02  ? 738  LEU B CG  1 
ATOM   9743  C CD1 . LEU B 1 738 ? 125.632 107.912 136.510 1.00 26.02  ? 738  LEU B CD1 1 
ATOM   9744  C CD2 . LEU B 1 738 ? 126.435 109.904 137.740 1.00 26.02  ? 738  LEU B CD2 1 
ATOM   9745  N N   . PHE B 1 739 ? 130.420 105.859 136.409 1.00 27.92  ? 739  PHE B N   1 
ATOM   9746  C CA  . PHE B 1 739 ? 131.501 105.827 135.438 1.00 27.92  ? 739  PHE B CA  1 
ATOM   9747  C C   . PHE B 1 739 ? 131.423 104.613 134.535 1.00 27.92  ? 739  PHE B C   1 
ATOM   9748  O O   . PHE B 1 739 ? 131.455 104.755 133.314 1.00 27.92  ? 739  PHE B O   1 
ATOM   9749  C CB  . PHE B 1 739 ? 132.859 105.853 136.135 1.00 27.92  ? 739  PHE B CB  1 
ATOM   9750  C CG  . PHE B 1 739 ? 134.020 105.720 135.195 1.00 27.92  ? 739  PHE B CG  1 
ATOM   9751  C CD1 . PHE B 1 739 ? 134.915 104.672 135.325 1.00 27.92  ? 739  PHE B CD1 1 
ATOM   9752  C CD2 . PHE B 1 739 ? 134.217 106.641 134.182 1.00 27.92  ? 739  PHE B CD2 1 
ATOM   9753  C CE1 . PHE B 1 739 ? 135.987 104.546 134.464 1.00 27.92  ? 739  PHE B CE1 1 
ATOM   9754  C CE2 . PHE B 1 739 ? 135.284 106.519 133.317 1.00 27.92  ? 739  PHE B CE2 1 
ATOM   9755  C CZ  . PHE B 1 739 ? 136.170 105.470 133.461 1.00 27.92  ? 739  PHE B CZ  1 
ATOM   9756  N N   . LEU B 1 740 ? 131.306 103.423 135.105 1.00 24.72  ? 740  LEU B N   1 
ATOM   9757  C CA  . LEU B 1 740 ? 131.149 102.214 134.317 1.00 24.72  ? 740  LEU B CA  1 
ATOM   9758  C C   . LEU B 1 740 ? 129.808 102.150 133.614 1.00 24.72  ? 740  LEU B C   1 
ATOM   9759  O O   . LEU B 1 740 ? 129.748 101.690 132.474 1.00 24.72  ? 740  LEU B O   1 
ATOM   9760  C CB  . LEU B 1 740 ? 131.330 100.984 135.206 1.00 24.72  ? 740  LEU B CB  1 
ATOM   9761  C CG  . LEU B 1 740 ? 132.790 100.663 135.516 1.00 24.72  ? 740  LEU B CG  1 
ATOM   9762  C CD1 . LEU B 1 740 ? 132.884 99.401  136.317 1.00 24.72  ? 740  LEU B CD1 1 
ATOM   9763  C CD2 . LEU B 1 740 ? 133.604 100.543 134.243 1.00 24.72  ? 740  LEU B CD2 1 
ATOM   9764  N N   . ALA B 1 741 ? 128.742 102.628 134.246 1.00 18.50  ? 741  ALA B N   1 
ATOM   9765  C CA  . ALA B 1 741 ? 127.440 102.690 133.609 1.00 18.50  ? 741  ALA B CA  1 
ATOM   9766  C C   . ALA B 1 741 ? 127.359 103.731 132.516 1.00 18.50  ? 741  ALA B C   1 
ATOM   9767  O O   . ALA B 1 741 ? 126.426 103.682 131.718 1.00 18.50  ? 741  ALA B O   1 
ATOM   9768  C CB  . ALA B 1 741 ? 126.359 102.991 134.635 1.00 18.50  ? 741  ALA B CB  1 
ATOM   9769  N N   . ALA B 1 742 ? 128.286 104.681 132.473 1.00 21.81  ? 742  ALA B N   1 
ATOM   9770  C CA  . ALA B 1 742 ? 128.409 105.591 131.349 1.00 21.81  ? 742  ALA B CA  1 
ATOM   9771  C C   . ALA B 1 742 ? 129.522 105.172 130.412 1.00 21.81  ? 742  ALA B C   1 
ATOM   9772  O O   . ALA B 1 742 ? 130.048 106.004 129.671 1.00 21.81  ? 742  ALA B O   1 
ATOM   9773  C CB  . ALA B 1 742 ? 128.636 107.018 131.833 1.00 21.81  ? 742  ALA B CB  1 
ATOM   9774  N N   . LEU B 1 743 ? 129.917 103.905 130.463 1.00 22.70  ? 743  LEU B N   1 
ATOM   9775  C CA  . LEU B 1 743 ? 130.764 103.290 129.454 1.00 22.70  ? 743  LEU B CA  1 
ATOM   9776  C C   . LEU B 1 743 ? 129.992 102.305 128.596 1.00 22.70  ? 743  LEU B C   1 
ATOM   9777  O O   . LEU B 1 743 ? 130.276 102.185 127.405 1.00 22.70  ? 743  LEU B O   1 
ATOM   9778  C CB  . LEU B 1 743 ? 131.950 102.579 130.107 1.00 22.70  ? 743  LEU B CB  1 
ATOM   9779  C CG  . LEU B 1 743 ? 133.182 103.419 130.406 1.00 22.70  ? 743  LEU B CG  1 
ATOM   9780  C CD1 . LEU B 1 743 ? 134.200 102.554 131.094 1.00 22.70  ? 743  LEU B CD1 1 
ATOM   9781  C CD2 . LEU B 1 743 ? 133.752 103.998 129.140 1.00 22.70  ? 743  LEU B CD2 1 
ATOM   9782  N N   . GLU B 1 744 ? 129.025 101.604 129.168 1.00 20.08  ? 744  GLU B N   1 
ATOM   9783  C CA  . GLU B 1 744 ? 128.116 100.798 128.380 1.00 20.08  ? 744  GLU B CA  1 
ATOM   9784  C C   . GLU B 1 744 ? 127.234 101.655 127.486 1.00 20.08  ? 744  GLU B C   1 
ATOM   9785  O O   . GLU B 1 744 ? 126.935 101.252 126.360 1.00 20.08  ? 744  GLU B O   1 
ATOM   9786  C CB  . GLU B 1 744 ? 127.287 99.917  129.314 1.00 20.08  ? 744  GLU B CB  1 
ATOM   9787  C CG  . GLU B 1 744 ? 125.965 99.396  128.786 1.00 20.08  ? 744  GLU B CG  1 
ATOM   9788  C CD  . GLU B 1 744 ? 126.090 98.436  127.604 1.00 20.08  ? 744  GLU B CD  1 
ATOM   9789  O OE1 . GLU B 1 744 ? 127.158 97.818  127.412 1.00 20.08  ? 744  GLU B OE1 1 
ATOM   9790  O OE2 . GLU B 1 744 ? 125.097 98.279  126.865 1.00 20.08  ? 744  GLU B OE2 1 
ATOM   9791  N N   . VAL B 1 745 ? 126.865 102.859 127.929 1.00 14.46  ? 745  VAL B N   1 
ATOM   9792  C CA  . VAL B 1 745 ? 126.184 103.818 127.057 1.00 14.46  ? 745  VAL B CA  1 
ATOM   9793  C C   . VAL B 1 745 ? 127.125 104.366 125.985 1.00 14.46  ? 745  VAL B C   1 
ATOM   9794  O O   . VAL B 1 745 ? 126.663 104.787 124.925 1.00 14.46  ? 745  VAL B O   1 
ATOM   9795  C CB  . VAL B 1 745 ? 125.563 104.925 127.929 1.00 14.46  ? 745  VAL B CB  1 
ATOM   9796  C CG1 . VAL B 1 745 ? 124.680 105.839 127.154 1.00 14.46  ? 745  VAL B CG1 1 
ATOM   9797  C CG2 . VAL B 1 745 ? 124.737 104.309 129.005 1.00 14.46  ? 745  VAL B CG2 1 
ATOM   9798  N N   . ILE B 1 746 ? 128.443 104.334 126.211 1.00 20.68  ? 746  ILE B N   1 
ATOM   9799  C CA  . ILE B 1 746 ? 129.416 104.665 125.170 1.00 20.68  ? 746  ILE B CA  1 
ATOM   9800  C C   . ILE B 1 746 ? 129.703 103.466 124.281 1.00 20.68  ? 746  ILE B C   1 
ATOM   9801  O O   . ILE B 1 746 ? 129.979 103.640 123.083 1.00 20.68  ? 746  ILE B O   1 
ATOM   9802  C CB  . ILE B 1 746 ? 130.676 105.249 125.842 1.00 20.68  ? 746  ILE B CB  1 
ATOM   9803  C CG1 . ILE B 1 746 ? 130.335 106.621 126.418 1.00 20.68  ? 746  ILE B CG1 1 
ATOM   9804  C CG2 . ILE B 1 746 ? 131.857 105.369 124.900 1.00 20.68  ? 746  ILE B CG2 1 
ATOM   9805  C CD1 . ILE B 1 746 ? 131.512 107.447 126.890 1.00 20.68  ? 746  ILE B CD1 1 
ATOM   9806  N N   . ARG B 1 747 ? 129.564 102.247 124.807 1.00 35.55  ? 747  ARG B N   1 
ATOM   9807  C CA  . ARG B 1 747 ? 129.748 101.042 124.007 1.00 35.55  ? 747  ARG B CA  1 
ATOM   9808  C C   . ARG B 1 747 ? 128.715 100.930 122.904 1.00 35.55  ? 747  ARG B C   1 
ATOM   9809  O O   . ARG B 1 747 ? 129.076 100.845 121.732 1.00 35.55  ? 747  ARG B O   1 
ATOM   9810  C CB  . ARG B 1 747 ? 129.685 99.802  124.883 1.00 35.55  ? 747  ARG B CB  1 
ATOM   9811  C CG  . ARG B 1 747 ? 129.696 98.568  124.066 1.00 35.55  ? 747  ARG B CG  1 
ATOM   9812  C CD  . ARG B 1 747 ? 129.375 97.360  124.881 1.00 35.55  ? 747  ARG B CD  1 
ATOM   9813  N NE  . ARG B 1 747 ? 127.956 97.194  125.132 1.00 35.55  ? 747  ARG B NE  1 
ATOM   9814  C CZ  . ARG B 1 747 ? 127.084 96.734  124.248 1.00 35.55  ? 747  ARG B CZ  1 
ATOM   9815  N NH1 . ARG B 1 747 ? 127.456 96.428  123.018 1.00 35.55  ? 747  ARG B NH1 1 
ATOM   9816  N NH2 . ARG B 1 747 ? 125.822 96.605  124.596 1.00 35.55  ? 747  ARG B NH2 1 
ATOM   9817  N N   . ARG B 1 748 ? 127.439 100.934 123.244 1.00 35.55  ? 748  ARG B N   1 
ATOM   9818  C CA  . ARG B 1 748 ? 126.413 101.075 122.226 1.00 35.55  ? 748  ARG B CA  1 
ATOM   9819  C C   . ARG B 1 748 ? 126.437 102.514 121.766 1.00 35.55  ? 748  ARG B C   1 
ATOM   9820  O O   . ARG B 1 748 ? 126.206 103.426 122.548 1.00 35.55  ? 748  ARG B O   1 
ATOM   9821  C CB  . ARG B 1 748 ? 125.053 100.717 122.769 1.00 35.55  ? 748  ARG B CB  1 
ATOM   9822  C CG  . ARG B 1 748 ? 124.030 100.664 121.733 1.00 35.55  ? 748  ARG B CG  1 
ATOM   9823  C CD  . ARG B 1 748 ? 122.812 100.259 122.410 1.00 35.55  ? 748  ARG B CD  1 
ATOM   9824  N NE  . ARG B 1 748 ? 123.053 99.013  123.099 1.00 35.55  ? 748  ARG B NE  1 
ATOM   9825  C CZ  . ARG B 1 748 ? 122.888 97.824  122.560 1.00 35.55  ? 748  ARG B CZ  1 
ATOM   9826  N NH1 . ARG B 1 748 ? 122.419 97.718  121.336 1.00 35.55  ? 748  ARG B NH1 1 
ATOM   9827  N NH2 . ARG B 1 748 ? 123.136 96.747  123.267 1.00 35.55  ? 748  ARG B NH2 1 
ATOM   9828  N N   . GLY B 1 749 ? 126.685 102.726 120.494 1.00 25.94  ? 749  GLY B N   1 
ATOM   9829  C CA  . GLY B 1 749 ? 127.005 104.047 120.028 1.00 25.94  ? 749  GLY B CA  1 
ATOM   9830  C C   . GLY B 1 749 ? 128.065 103.845 118.987 1.00 25.94  ? 749  GLY B C   1 
ATOM   9831  O O   . GLY B 1 749 ? 128.170 104.625 118.043 1.00 25.94  ? 749  GLY B O   1 
ATOM   9832  N N   . GLN B 1 750 ? 128.860 102.789 119.155 1.00 29.82  ? 750  GLN B N   1 
ATOM   9833  C CA  . GLN B 1 750 ? 129.564 102.195 118.031 1.00 29.82  ? 750  GLN B CA  1 
ATOM   9834  C C   . GLN B 1 750 ? 128.933 100.895 117.587 1.00 29.82  ? 750  GLN B C   1 
ATOM   9835  O O   . GLN B 1 750 ? 129.200 100.449 116.474 1.00 29.82  ? 750  GLN B O   1 
ATOM   9836  C CB  . GLN B 1 750 ? 131.033 101.930 118.353 1.00 29.82  ? 750  GLN B CB  1 
ATOM   9837  C CG  . GLN B 1 750 ? 131.261 100.807 119.313 1.00 29.82  ? 750  GLN B CG  1 
ATOM   9838  C CD  . GLN B 1 750 ? 132.717 100.507 119.489 1.00 29.82  ? 750  GLN B CD  1 
ATOM   9839  O OE1 . GLN B 1 750 ? 133.567 101.089 118.817 1.00 29.82  ? 750  GLN B OE1 1 
ATOM   9840  N NE2 . GLN B 1 750 ? 133.022 99.591  120.395 1.00 29.82  ? 750  GLN B NE2 1 
ATOM   9841  N N   . TRP B 1 751 ? 128.121 100.274 118.426 1.00 35.55  ? 751  TRP B N   1 
ATOM   9842  C CA  . TRP B 1 751 ? 127.296 99.189  117.947 1.00 35.55  ? 751  TRP B CA  1 
ATOM   9843  C C   . TRP B 1 751 ? 126.238 99.698  116.993 1.00 35.55  ? 751  TRP B C   1 
ATOM   9844  O O   . TRP B 1 751 ? 125.843 98.966  116.090 1.00 35.55  ? 751  TRP B O   1 
ATOM   9845  C CB  . TRP B 1 751 ? 126.642 98.468  119.117 1.00 35.55  ? 751  TRP B CB  1 
ATOM   9846  C CG  . TRP B 1 751 ? 125.741 97.333  118.759 1.00 35.55  ? 751  TRP B CG  1 
ATOM   9847  C CD1 . TRP B 1 751 ? 126.062 96.026  118.790 1.00 35.55  ? 751  TRP B CD1 1 
ATOM   9848  C CD2 . TRP B 1 751 ? 124.358 97.395  118.383 1.00 35.55  ? 751  TRP B CD2 1 
ATOM   9849  N NE1 . TRP B 1 751 ? 124.991 95.265  118.429 1.00 35.55  ? 751  TRP B NE1 1 
ATOM   9850  C CE2 . TRP B 1 751 ? 123.930 96.088  118.175 1.00 35.55  ? 751  TRP B CE2 1 
ATOM   9851  C CE3 . TRP B 1 751 ? 123.450 98.431  118.191 1.00 35.55  ? 751  TRP B CE3 1 
ATOM   9852  C CZ2 . TRP B 1 751 ? 122.643 95.788  117.783 1.00 35.55  ? 751  TRP B CZ2 1 
ATOM   9853  C CZ3 . TRP B 1 751 ? 122.188 98.134  117.793 1.00 35.55  ? 751  TRP B CZ3 1 
ATOM   9854  C CH2 . TRP B 1 751 ? 121.788 96.828  117.596 1.00 35.55  ? 751  TRP B CH2 1 
ATOM   9855  N N   . ASN B 1 752 ? 125.732 100.920 117.190 1.00 32.82  ? 752  ASN B N   1 
ATOM   9856  C CA  . ASN B 1 752 ? 124.736 101.466 116.269 1.00 32.82  ? 752  ASN B CA  1 
ATOM   9857  C C   . ASN B 1 752 ? 125.321 101.695 114.893 1.00 32.82  ? 752  ASN B C   1 
ATOM   9858  O O   . ASN B 1 752 ? 124.604 101.623 113.895 1.00 32.82  ? 752  ASN B O   1 
ATOM   9859  C CB  . ASN B 1 752 ? 124.188 102.791 116.779 1.00 32.82  ? 752  ASN B CB  1 
ATOM   9860  C CG  . ASN B 1 752 ? 123.495 102.662 118.079 1.00 32.82  ? 752  ASN B CG  1 
ATOM   9861  O OD1 . ASN B 1 752 ? 123.014 101.597 118.424 1.00 32.82  ? 752  ASN B OD1 1 
ATOM   9862  N ND2 . ASN B 1 752 ? 123.416 103.752 118.815 1.00 32.82  ? 752  ASN B ND2 1 
ATOM   9863  N N   . PHE B 1 753 ? 126.609 101.991 114.829 1.00 30.77  ? 753  PHE B N   1 
ATOM   9864  C CA  . PHE B 1 753 ? 127.249 102.190 113.545 1.00 30.77  ? 753  PHE B CA  1 
ATOM   9865  C C   . PHE B 1 753 ? 127.317 100.892 112.756 1.00 30.77  ? 753  PHE B C   1 
ATOM   9866  O O   . PHE B 1 753 ? 126.751 100.791 111.663 1.00 30.77  ? 753  PHE B O   1 
ATOM   9867  C CB  . PHE B 1 753 ? 128.641 102.760 113.749 1.00 30.77  ? 753  PHE B CB  1 
ATOM   9868  C CG  . PHE B 1 753 ? 129.199 103.374 112.529 1.00 30.77  ? 753  PHE B CG  1 
ATOM   9869  C CD1 . PHE B 1 753 ? 128.422 104.222 111.769 1.00 30.77  ? 753  PHE B CD1 1 
ATOM   9870  C CD2 . PHE B 1 753 ? 130.481 103.097 112.123 1.00 30.77  ? 753  PHE B CD2 1 
ATOM   9871  C CE1 . PHE B 1 753 ? 128.912 104.795 110.642 1.00 30.77  ? 753  PHE B CE1 1 
ATOM   9872  C CE2 . PHE B 1 753 ? 130.978 103.665 110.986 1.00 30.77  ? 753  PHE B CE2 1 
ATOM   9873  C CZ  . PHE B 1 753 ? 130.188 104.515 110.241 1.00 30.77  ? 753  PHE B CZ  1 
ATOM   9874  N N   . TYR B 1 754 ? 127.967 99.875  113.310 1.00 35.55  ? 754  TYR B N   1 
ATOM   9875  C CA  . TYR B 1 754 ? 128.227 98.647  112.588 1.00 35.55  ? 754  TYR B CA  1 
ATOM   9876  C C   . TYR B 1 754 ? 127.028 97.726  112.535 1.00 35.55  ? 754  TYR B C   1 
ATOM   9877  O O   . TYR B 1 754 ? 127.108 96.669  111.918 1.00 35.55  ? 754  TYR B O   1 
ATOM   9878  C CB  . TYR B 1 754 ? 129.414 97.928  113.202 1.00 35.55  ? 754  TYR B CB  1 
ATOM   9879  C CG  . TYR B 1 754 ? 130.690 98.690  113.050 1.00 35.55  ? 754  TYR B CG  1 
ATOM   9880  C CD1 . TYR B 1 754 ? 131.333 98.755  111.837 1.00 35.55  ? 754  TYR B CD1 1 
ATOM   9881  C CD2 . TYR B 1 754 ? 131.256 99.342  114.122 1.00 35.55  ? 754  TYR B CD2 1 
ATOM   9882  C CE1 . TYR B 1 754 ? 132.507 99.454  111.694 1.00 35.55  ? 754  TYR B CE1 1 
ATOM   9883  C CE2 . TYR B 1 754 ? 132.428 100.043 113.989 1.00 35.55  ? 754  TYR B CE2 1 
ATOM   9884  C CZ  . TYR B 1 754 ? 133.048 100.096 112.775 1.00 35.55  ? 754  TYR B CZ  1 
ATOM   9885  O OH  . TYR B 1 754 ? 134.219 100.797 112.646 1.00 35.55  ? 754  TYR B OH  1 
ATOM   9886  N N   . ARG B 1 755 ? 125.924 98.080  113.158 1.00 35.55  ? 755  ARG B N   1 
ATOM   9887  C CA  . ARG B 1 755 ? 124.702 97.359  112.884 1.00 35.55  ? 755  ARG B CA  1 
ATOM   9888  C C   . ARG B 1 755 ? 123.976 97.925  111.679 1.00 35.55  ? 755  ARG B C   1 
ATOM   9889  O O   . ARG B 1 755 ? 123.381 97.160  110.915 1.00 35.55  ? 755  ARG B O   1 
ATOM   9890  C CB  . ARG B 1 755 ? 123.791 97.375  114.112 1.00 35.55  ? 755  ARG B CB  1 
ATOM   9891  C CG  . ARG B 1 755 ? 122.409 96.809  113.938 1.00 35.55  ? 755  ARG B CG  1 
ATOM   9892  C CD  . ARG B 1 755 ? 122.400 95.385  113.442 1.00 35.55  ? 755  ARG B CD  1 
ATOM   9893  N NE  . ARG B 1 755 ? 121.167 95.138  112.711 1.00 35.55  ? 755  ARG B NE  1 
ATOM   9894  C CZ  . ARG B 1 755 ? 120.550 93.967  112.651 1.00 35.55  ? 755  ARG B CZ  1 
ATOM   9895  N NH1 . ARG B 1 755 ? 121.056 92.915  113.275 1.00 35.55  ? 755  ARG B NH1 1 
ATOM   9896  N NH2 . ARG B 1 755 ? 119.420 93.850  111.966 1.00 35.55  ? 755  ARG B NH2 1 
ATOM   9897  N N   . LEU B 1 756 ? 124.054 99.233  111.449 1.00 26.01  ? 756  LEU B N   1 
ATOM   9898  C CA  . LEU B 1 756 ? 123.456 99.848  110.272 1.00 26.01  ? 756  LEU B CA  1 
ATOM   9899  C C   . LEU B 1 756 ? 124.308 99.736  109.026 1.00 26.01  ? 756  LEU B C   1 
ATOM   9900  O O   . LEU B 1 756 ? 123.752 99.599  107.937 1.00 26.01  ? 756  LEU B O   1 
ATOM   9901  C CB  . LEU B 1 756 ? 123.147 101.323 110.530 1.00 26.01  ? 756  LEU B CB  1 
ATOM   9902  C CG  . LEU B 1 756 ? 121.697 101.611 110.880 1.00 26.01  ? 756  LEU B CG  1 
ATOM   9903  C CD1 . LEU B 1 756 ? 120.913 101.298 109.674 1.00 26.01  ? 756  LEU B CD1 1 
ATOM   9904  C CD2 . LEU B 1 756 ? 121.178 100.784 112.013 1.00 26.01  ? 756  LEU B CD2 1 
ATOM   9905  N N   . GLU B 1 757 ? 125.634 99.806  109.159 1.00 30.31  ? 757  GLU B N   1 
ATOM   9906  C CA  . GLU B 1 757 ? 126.514 99.542  108.028 1.00 30.31  ? 757  GLU B CA  1 
ATOM   9907  C C   . GLU B 1 757 ? 126.317 98.125  107.511 1.00 30.31  ? 757  GLU B C   1 
ATOM   9908  O O   . GLU B 1 757 ? 126.222 97.902  106.303 1.00 30.31  ? 757  GLU B O   1 
ATOM   9909  C CB  . GLU B 1 757 ? 127.962 99.780  108.437 1.00 30.31  ? 757  GLU B CB  1 
ATOM   9910  C CG  . GLU B 1 757 ? 128.950 99.028  107.599 1.00 30.31  ? 757  GLU B CG  1 
ATOM   9911  C CD  . GLU B 1 757 ? 130.367 99.219  108.048 1.00 30.31  ? 757  GLU B CD  1 
ATOM   9912  O OE1 . GLU B 1 757 ? 130.775 100.378 108.245 1.00 30.31  ? 757  GLU B OE1 1 
ATOM   9913  O OE2 . GLU B 1 757 ? 131.085 98.210  108.191 1.00 30.31  ? 757  GLU B OE2 1 
ATOM   9914  N N   . ASN B 1 758 ? 126.195 97.166  108.427 1.00 25.19  ? 758  ASN B N   1 
ATOM   9915  C CA  . ASN B 1 758 ? 125.936 95.783  108.056 1.00 25.19  ? 758  ASN B CA  1 
ATOM   9916  C C   . ASN B 1 758 ? 124.584 95.607  107.399 1.00 25.19  ? 758  ASN B C   1 
ATOM   9917  O O   . ASN B 1 758 ? 124.493 94.940  106.368 1.00 25.19  ? 758  ASN B O   1 
ATOM   9918  C CB  . ASN B 1 758 ? 126.000 94.876  109.273 1.00 25.19  ? 758  ASN B CB  1 
ATOM   9919  C CG  . ASN B 1 758 ? 125.601 93.461  108.947 1.00 25.19  ? 758  ASN B CG  1 
ATOM   9920  O OD1 . ASN B 1 758 ? 126.300 92.777  108.213 1.00 25.19  ? 758  ASN B OD1 1 
ATOM   9921  N ND2 . ASN B 1 758 ? 124.468 93.017  109.474 1.00 25.19  ? 758  ASN B ND2 1 
ATOM   9922  N N   . GLU B 1 759 ? 123.529 96.185  107.956 1.00 21.05  ? 759  GLU B N   1 
ATOM   9923  C CA  . GLU B 1 759 ? 122.229 96.045  107.323 1.00 21.05  ? 759  GLU B CA  1 
ATOM   9924  C C   . GLU B 1 759 ? 121.942 97.154  106.325 1.00 21.05  ? 759  GLU B C   1 
ATOM   9925  O O   . GLU B 1 759 ? 120.772 97.461  106.089 1.00 21.05  ? 759  GLU B O   1 
ATOM   9926  C CB  . GLU B 1 759 ? 121.115 95.969  108.364 1.00 21.05  ? 759  GLU B CB  1 
ATOM   9927  C CG  . GLU B 1 759 ? 121.053 94.615  109.076 1.00 21.05  ? 759  GLU B CG  1 
ATOM   9928  C CD  . GLU B 1 759 ? 120.565 93.468  108.189 1.00 21.05  ? 759  GLU B CD  1 
ATOM   9929  O OE1 . GLU B 1 759 ? 119.646 93.692  107.377 1.00 21.05  ? 759  GLU B OE1 1 
ATOM   9930  O OE2 . GLU B 1 759 ? 121.094 92.339  108.307 1.00 21.05  ? 759  GLU B OE2 1 
ATOM   9931  N N   . HIS B 1 760 ? 122.981 97.779  105.767 1.00 25.16  ? 760  HIS B N   1 
ATOM   9932  C CA  . HIS B 1 760 ? 122.914 98.407  104.453 1.00 25.16  ? 760  HIS B CA  1 
ATOM   9933  C C   . HIS B 1 760 ? 123.763 97.680  103.423 1.00 25.16  ? 760  HIS B C   1 
ATOM   9934  O O   . HIS B 1 760 ? 123.290 97.440  102.310 1.00 25.16  ? 760  HIS B O   1 
ATOM   9935  C CB  . HIS B 1 760 ? 123.350 99.870  104.505 1.00 25.16  ? 760  HIS B CB  1 
ATOM   9936  C CG  . HIS B 1 760 ? 123.080 100.614 103.235 1.00 25.16  ? 760  HIS B CG  1 
ATOM   9937  N ND1 . HIS B 1 760 ? 124.076 101.194 102.486 1.00 25.16  ? 760  HIS B ND1 1 
ATOM   9938  C CD2 . HIS B 1 760 ? 121.924 100.860 102.573 1.00 25.16  ? 760  HIS B CD2 1 
ATOM   9939  C CE1 . HIS B 1 760 ? 123.549 101.776 101.424 1.00 25.16  ? 760  HIS B CE1 1 
ATOM   9940  N NE2 . HIS B 1 760 ? 122.243 101.588 101.453 1.00 25.16  ? 760  HIS B NE2 1 
ATOM   9941  N N   . LEU B 1 761 ? 124.989 97.273  103.787 1.00 20.05  ? 761  LEU B N   1 
ATOM   9942  C CA  . LEU B 1 761 ? 125.772 96.384  102.933 1.00 20.05  ? 761  LEU B CA  1 
ATOM   9943  C C   . LEU B 1 761 ? 125.210 94.972  102.891 1.00 20.05  ? 761  LEU B C   1 
ATOM   9944  O O   . LEU B 1 761 ? 125.764 94.116  102.198 1.00 20.05  ? 761  LEU B O   1 
ATOM   9945  C CB  . LEU B 1 761 ? 127.225 96.302  103.380 1.00 20.05  ? 761  LEU B CB  1 
ATOM   9946  C CG  . LEU B 1 761 ? 128.165 97.467  103.148 1.00 20.05  ? 761  LEU B CG  1 
ATOM   9947  C CD1 . LEU B 1 761 ? 129.551 97.081  103.635 1.00 20.05  ? 761  LEU B CD1 1 
ATOM   9948  C CD2 . LEU B 1 761 ? 128.179 97.804  101.684 1.00 20.05  ? 761  LEU B CD2 1 
ATOM   9949  N N   . ASN B 1 762 ? 124.167 94.683  103.659 1.00 17.19  ? 762  ASN B N   1 
ATOM   9950  C CA  . ASN B 1 762 ? 123.299 93.553  103.383 1.00 17.19  ? 762  ASN B CA  1 
ATOM   9951  C C   . ASN B 1 762 ? 121.840 93.988  103.312 1.00 17.19  ? 762  ASN B C   1 
ATOM   9952  O O   . ASN B 1 762 ? 120.942 93.249  103.732 1.00 17.19  ? 762  ASN B O   1 
ATOM   9953  C CB  . ASN B 1 762 ? 123.543 92.459  104.411 1.00 17.19  ? 762  ASN B CB  1 
ATOM   9954  C CG  . ASN B 1 762 ? 125.004 92.038  104.441 1.00 17.19  ? 762  ASN B CG  1 
ATOM   9955  O OD1 . ASN B 1 762 ? 125.731 92.325  105.385 1.00 17.19  ? 762  ASN B OD1 1 
ATOM   9956  N ND2 . ASN B 1 762 ? 125.447 91.387  103.380 1.00 17.19  ? 762  ASN B ND2 1 
ATOM   9957  N N   . ASN B 1 763 ? 121.612 95.208  102.806 1.00 32.82  ? 763  ASN B N   1 
ATOM   9958  C CA  . ASN B 1 763 ? 120.346 95.670  102.248 1.00 32.82  ? 763  ASN B CA  1 
ATOM   9959  C C   . ASN B 1 763 ? 120.421 95.951  100.750 1.00 32.82  ? 763  ASN B C   1 
ATOM   9960  O O   . ASN B 1 763 ? 119.393 95.866  100.070 1.00 32.82  ? 763  ASN B O   1 
ATOM   9961  C CB  . ASN B 1 763 ? 119.870 96.939  102.965 1.00 32.82  ? 763  ASN B CB  1 
ATOM   9962  C CG  . ASN B 1 763 ? 118.375 97.145  102.856 1.00 32.82  ? 763  ASN B CG  1 
ATOM   9963  O OD1 . ASN B 1 763 ? 117.629 96.231  102.526 1.00 32.82  ? 763  ASN B OD1 1 
ATOM   9964  N ND2 . ASN B 1 763 ? 117.931 98.350  103.154 1.00 32.82  ? 763  ASN B ND2 1 
ATOM   9965  N N   . ALA B 1 764 ? 121.606 96.341  100.251 1.00 35.48  ? 764  ALA B N   1 
ATOM   9966  C CA  . ALA B 1 764 ? 122.005 96.396  98.840  1.00 35.48  ? 764  ALA B CA  1 
ATOM   9967  C C   . ALA B 1 764 ? 121.316 97.484  98.010  1.00 35.48  ? 764  ALA B C   1 
ATOM   9968  O O   . ALA B 1 764 ? 121.564 97.586  96.804  1.00 35.48  ? 764  ALA B O   1 
ATOM   9969  C CB  . ALA B 1 764 ? 121.812 95.026  98.175  1.00 35.48  ? 764  ALA B CB  1 
ATOM   9970  N N   . GLY B 1 765 ? 120.460 98.300  98.628  1.00 39.76  ? 765  GLY B N   1 
ATOM   9971  C CA  . GLY B 1 765 ? 119.872 99.456  97.970  1.00 39.76  ? 765  GLY B CA  1 
ATOM   9972  C C   . GLY B 1 765 ? 120.525 100.747 98.424  1.00 39.76  ? 765  GLY B C   1 
ATOM   9973  O O   . GLY B 1 765 ? 121.177 100.762 99.471  1.00 39.76  ? 765  GLY B O   1 
ATOM   9974  N N   . LYS B 1 766 ? 120.373 101.836 97.660  1.00 41.99  ? 766  LYS B N   1 
ATOM   9975  C CA  . LYS B 1 766 ? 121.063 103.088 97.977  1.00 41.99  ? 766  LYS B CA  1 
ATOM   9976  C C   . LYS B 1 766 ? 120.124 104.284 97.819  1.00 41.99  ? 766  LYS B C   1 
ATOM   9977  O O   . LYS B 1 766 ? 120.492 105.312 97.243  1.00 41.99  ? 766  LYS B O   1 
ATOM   9978  C CB  . LYS B 1 766 ? 122.323 103.258 97.127  1.00 41.99  ? 766  LYS B CB  1 
ATOM   9979  C CG  . LYS B 1 766 ? 123.500 102.433 97.626  1.00 41.99  ? 766  LYS B CG  1 
ATOM   9980  C CD  . LYS B 1 766 ? 124.604 102.329 96.596  1.00 41.99  ? 766  LYS B CD  1 
ATOM   9981  C CE  . LYS B 1 766 ? 124.285 101.293 95.526  1.00 41.99  ? 766  LYS B CE  1 
ATOM   9982  N NZ  . LYS B 1 766 ? 124.315 99.898  96.042  1.00 41.99  ? 766  LYS B NZ  1 
ATOM   9983  N N   . PHE B 1 767 ? 118.922 104.174 98.373  1.00 38.40  ? 767  PHE B N   1 
ATOM   9984  C CA  . PHE B 1 767 ? 117.856 105.165 98.224  1.00 38.40  ? 767  PHE B CA  1 
ATOM   9985  C C   . PHE B 1 767 ? 118.178 106.403 99.049  1.00 38.40  ? 767  PHE B C   1 
ATOM   9986  O O   . PHE B 1 767 ? 117.621 106.591 100.132 1.00 38.40  ? 767  PHE B O   1 
ATOM   9987  C CB  . PHE B 1 767 ? 116.517 104.622 98.720  1.00 38.40  ? 767  PHE B CB  1 
ATOM   9988  C CG  . PHE B 1 767 ? 115.992 103.420 97.997  1.00 38.40  ? 767  PHE B CG  1 
ATOM   9989  C CD1 . PHE B 1 767 ? 114.887 103.545 97.190  1.00 38.40  ? 767  PHE B CD1 1 
ATOM   9990  C CD2 . PHE B 1 767 ? 116.527 102.158 98.194  1.00 38.40  ? 767  PHE B CD2 1 
ATOM   9991  C CE1 . PHE B 1 767 ? 114.359 102.456 96.554  1.00 38.40  ? 767  PHE B CE1 1 
ATOM   9992  C CE2 . PHE B 1 767 ? 116.007 101.062 97.548  1.00 38.40  ? 767  PHE B CE2 1 
ATOM   9993  C CZ  . PHE B 1 767 ? 114.920 101.213 96.724  1.00 38.40  ? 767  PHE B CZ  1 
ATOM   9994  N N   . ARG B 1 768 ? 119.035 107.283 98.549  1.00 45.33  ? 768  ARG B N   1 
ATOM   9995  C CA  . ARG B 1 768 ? 119.245 108.560 99.232  1.00 45.33  ? 768  ARG B CA  1 
ATOM   9996  C C   . ARG B 1 768 ? 118.338 109.629 98.627  1.00 45.33  ? 768  ARG B C   1 
ATOM   9997  O O   . ARG B 1 768 ? 118.508 110.074 97.493  1.00 45.33  ? 768  ARG B O   1 
ATOM   9998  C CB  . ARG B 1 768 ? 120.709 108.973 99.173  1.00 45.33  ? 768  ARG B CB  1 
ATOM   9999  C CG  . ARG B 1 768 ? 121.423 108.885 100.498 1.00 45.33  ? 768  ARG B CG  1 
ATOM   10000 C CD  . ARG B 1 768 ? 122.850 109.367 100.358 1.00 45.33  ? 768  ARG B CD  1 
ATOM   10001 N NE  . ARG B 1 768 ? 123.649 108.444 99.559  1.00 45.33  ? 768  ARG B NE  1 
ATOM   10002 C CZ  . ARG B 1 768 ? 124.647 108.812 98.765  1.00 45.33  ? 768  ARG B CZ  1 
ATOM   10003 N NH1 . ARG B 1 768 ? 124.979 110.091 98.669  1.00 45.33  ? 768  ARG B NH1 1 
ATOM   10004 N NH2 . ARG B 1 768 ? 125.314 107.902 98.070  1.00 45.33  ? 768  ARG B NH2 1 
ATOM   10005 N N   . ALA B 1 769 ? 117.352 110.045 99.424  1.00 49.70  ? 769  ALA B N   1 
ATOM   10006 C CA  . ALA B 1 769 ? 116.661 111.301 99.158  1.00 49.70  ? 769  ALA B CA  1 
ATOM   10007 C C   . ALA B 1 769 ? 117.662 112.419 99.401  1.00 49.70  ? 769  ALA B C   1 
ATOM   10008 O O   . ALA B 1 769 ? 118.617 112.219 100.160 1.00 49.70  ? 769  ALA B O   1 
ATOM   10009 C CB  . ALA B 1 769 ? 115.423 111.463 100.038 1.00 49.70  ? 769  ALA B CB  1 
ATOM   10010 N N   . VAL B 1 770 ? 117.417 113.595 98.817  1.00 52.63  ? 770  VAL B N   1 
ATOM   10011 C CA  . VAL B 1 770 ? 118.456 114.563 98.461  1.00 52.63  ? 770  VAL B CA  1 
ATOM   10012 C C   . VAL B 1 770 ? 119.316 115.017 99.640  1.00 52.63  ? 770  VAL B C   1 
ATOM   10013 O O   . VAL B 1 770 ? 118.845 115.653 100.590 1.00 52.63  ? 770  VAL B O   1 
ATOM   10014 C CB  . VAL B 1 770 ? 117.822 115.757 97.713  1.00 52.63  ? 770  VAL B CB  1 
ATOM   10015 C CG1 . VAL B 1 770 ? 116.585 116.311 98.437  1.00 52.63  ? 770  VAL B CG1 1 
ATOM   10016 C CG2 . VAL B 1 770 ? 118.854 116.854 97.487  1.00 52.63  ? 770  VAL B CG2 1 
ATOM   10017 N N   . LYS B 1 771 ? 120.580 114.603 99.612  1.00 55.12  ? 771  LYS B N   1 
ATOM   10018 C CA  . LYS B 1 771 ? 121.545 115.009 100.619 1.00 55.12  ? 771  LYS B CA  1 
ATOM   10019 C C   . LYS B 1 771 ? 122.699 115.764 99.972  1.00 55.12  ? 771  LYS B C   1 
ATOM   10020 O O   . LYS B 1 771 ? 122.935 116.936 100.284 1.00 55.12  ? 771  LYS B O   1 
ATOM   10021 C CB  . LYS B 1 771 ? 122.039 113.779 101.385 1.00 55.12  ? 771  LYS B CB  1 
ATOM   10022 C CG  . LYS B 1 771 ? 123.303 113.986 102.206 1.00 55.12  ? 771  LYS B CG  1 
ATOM   10023 C CD  . LYS B 1 771 ? 124.068 112.686 102.352 1.00 55.12  ? 771  LYS B CD  1 
ATOM   10024 C CE  . LYS B 1 771 ? 125.423 112.916 102.974 1.00 55.12  ? 771  LYS B CE  1 
ATOM   10025 N NZ  . LYS B 1 771 ? 126.235 113.875 102.195 1.00 55.12  ? 771  LYS B NZ  1 
ATOM   10026 N N   . THR B 1 772 ? 123.380 115.115 99.031  1.00 66.98  ? 772  THR B N   1 
ATOM   10027 C CA  . THR B 1 772 ? 124.546 115.676 98.350  1.00 66.98  ? 772  THR B CA  1 
ATOM   10028 C C   . THR B 1 772 ? 124.695 115.089 96.952  1.00 66.98  ? 772  THR B C   1 
ATOM   10029 O O   . THR B 1 772 ? 125.039 113.917 96.791  1.00 66.98  ? 772  THR B O   1 
ATOM   10030 C CB  . THR B 1 772 ? 125.859 115.423 99.128  1.00 66.98  ? 772  THR B CB  1 
ATOM   10031 O OG1 . THR B 1 772 ? 126.063 114.015 99.297  1.00 66.98  ? 772  THR B OG1 1 
ATOM   10032 C CG2 . THR B 1 772 ? 125.872 116.140 100.474 1.00 66.98  ? 772  THR B CG2 1 
HETATM 10033 C C1  . IHP C 2 .   ? 103.566 130.761 88.669  1.00 111.14 ? 801  IHP A C1  1 
HETATM 10034 C C2  . IHP C 2 .   ? 104.928 131.393 88.475  1.00 111.14 ? 801  IHP A C2  1 
HETATM 10035 C C3  . IHP C 2 .   ? 105.465 131.504 87.062  1.00 111.14 ? 801  IHP A C3  1 
HETATM 10036 C C4  . IHP C 2 .   ? 104.416 131.955 86.057  1.00 111.14 ? 801  IHP A C4  1 
HETATM 10037 C C5  . IHP C 2 .   ? 103.138 131.146 86.083  1.00 111.14 ? 801  IHP A C5  1 
HETATM 10038 C C6  . IHP C 2 .   ? 102.685 130.650 87.438  1.00 111.14 ? 801  IHP A C6  1 
HETATM 10039 O O11 . IHP C 2 .   ? 102.880 131.488 89.676  1.00 111.14 ? 801  IHP A O11 1 
HETATM 10040 P P1  . IHP C 2 .   ? 101.823 130.793 90.694  1.00 111.14 ? 801  IHP A P1  1 
HETATM 10041 O O21 . IHP C 2 .   ? 101.635 131.868 91.731  1.00 111.14 ? 801  IHP A O21 1 
HETATM 10042 O O31 . IHP C 2 .   ? 100.552 130.558 89.899  1.00 111.14 ? 801  IHP A O31 1 
HETATM 10043 O O41 . IHP C 2 .   ? 102.576 129.533 91.141  1.00 111.14 ? 801  IHP A O41 1 
HETATM 10044 O O12 . IHP C 2 .   ? 105.773 130.520 89.199  1.00 111.14 ? 801  IHP A O12 1 
HETATM 10045 P P2  . IHP C 2 .   ? 106.467 130.839 90.623  1.00 111.14 ? 801  IHP A P2  1 
HETATM 10046 O O22 . IHP C 2 .   ? 106.291 129.584 91.459  1.00 111.14 ? 801  IHP A O22 1 
HETATM 10047 O O32 . IHP C 2 .   ? 105.637 131.950 91.210  1.00 111.14 ? 801  IHP A O32 1 
HETATM 10048 O O42 . IHP C 2 .   ? 107.882 131.105 90.117  1.00 111.14 ? 801  IHP A O42 1 
HETATM 10049 O O13 . IHP C 2 .   ? 105.932 130.238 86.669  1.00 111.14 ? 801  IHP A O13 1 
HETATM 10050 P P3  . IHP C 2 .   ? 107.454 129.822 86.271  1.00 111.14 ? 801  IHP A P3  1 
HETATM 10051 O O23 . IHP C 2 .   ? 107.620 130.153 84.818  1.00 111.14 ? 801  IHP A O23 1 
HETATM 10052 O O33 . IHP C 2 .   ? 108.412 130.551 87.196  1.00 111.14 ? 801  IHP A O33 1 
HETATM 10053 O O43 . IHP C 2 .   ? 107.431 128.340 86.565  1.00 111.14 ? 801  IHP A O43 1 
HETATM 10054 O O14 . IHP C 2 .   ? 104.853 131.681 84.728  1.00 111.14 ? 801  IHP A O14 1 
HETATM 10055 P P4  . IHP C 2 .   ? 105.490 132.682 83.659  1.00 111.14 ? 801  IHP A P4  1 
HETATM 10056 O O24 . IHP C 2 .   ? 105.257 131.921 82.374  1.00 111.14 ? 801  IHP A O24 1 
HETATM 10057 O O34 . IHP C 2 .   ? 104.640 133.934 83.790  1.00 111.14 ? 801  IHP A O34 1 
HETATM 10058 O O44 . IHP C 2 .   ? 106.964 132.826 84.036  1.00 111.14 ? 801  IHP A O44 1 
HETATM 10059 O O15 . IHP C 2 .   ? 102.049 131.851 85.493  1.00 111.14 ? 801  IHP A O15 1 
HETATM 10060 P P5  . IHP C 2 .   ? 101.090 131.280 84.323  1.00 111.14 ? 801  IHP A P5  1 
HETATM 10061 O O25 . IHP C 2 .   ? 101.491 129.842 84.045  1.00 111.14 ? 801  IHP A O25 1 
HETATM 10062 O O35 . IHP C 2 .   ? 101.383 132.198 83.144  1.00 111.14 ? 801  IHP A O35 1 
HETATM 10063 O O45 . IHP C 2 .   ? 99.779  131.464 85.054  1.00 111.14 ? 801  IHP A O45 1 
HETATM 10064 O O16 . IHP C 2 .   ? 102.771 129.277 87.157  1.00 111.14 ? 801  IHP A O16 1 
HETATM 10065 P P6  . IHP C 2 .   ? 101.522 128.311 87.190  1.00 111.14 ? 801  IHP A P6  1 
HETATM 10066 O O26 . IHP C 2 .   ? 101.111 128.517 88.633  1.00 111.14 ? 801  IHP A O26 1 
HETATM 10067 O O36 . IHP C 2 .   ? 102.258 127.032 86.766  1.00 111.14 ? 801  IHP A O36 1 
HETATM 10068 O O46 . IHP C 2 .   ? 100.532 128.896 86.220  1.00 111.14 ? 801  IHP A O46 1 
HETATM 10069 P P   . PO4 D 3 .   ? 134.304 164.036 123.473 1.00 26.02  ? 802  PO4 A P   1 
HETATM 10070 O O1  . PO4 D 3 .   ? 134.898 162.674 123.259 1.00 26.02  ? 802  PO4 A O1  1 
HETATM 10071 O O2  . PO4 D 3 .   ? 135.418 164.920 123.969 1.00 26.02  ? 802  PO4 A O2  1 
HETATM 10072 O O3  . PO4 D 3 .   ? 133.760 164.533 122.155 1.00 26.02  ? 802  PO4 A O3  1 
HETATM 10073 O O4  . PO4 D 3 .   ? 133.195 163.989 124.501 1.00 26.02  ? 802  PO4 A O4  1 
HETATM 10074 P P   . PO4 E 3 .   ? 122.986 93.229  123.464 1.00 23.68  ? 1001 PO4 B P   1 
HETATM 10075 O O1  . PO4 E 3 .   ? 122.395 94.593  123.251 1.00 23.68  ? 1001 PO4 B O1  1 
HETATM 10076 O O2  . PO4 E 3 .   ? 121.871 92.346  123.958 1.00 23.68  ? 1001 PO4 B O2  1 
HETATM 10077 O O3  . PO4 E 3 .   ? 123.530 92.733  122.144 1.00 23.68  ? 1001 PO4 B O3  1 
HETATM 10078 O O4  . PO4 E 3 .   ? 124.096 93.272  124.491 1.00 23.68  ? 1001 PO4 B O4  1 
HETATM 10079 C C1  . IHP F 2 .   ? 153.788 126.494 88.707  1.00 107.62 ? 1002 IHP B C1  1 
HETATM 10080 C C2  . IHP F 2 .   ? 152.425 125.865 88.512  1.00 107.62 ? 1002 IHP B C2  1 
HETATM 10081 C C3  . IHP F 2 .   ? 151.888 125.757 87.099  1.00 107.62 ? 1002 IHP B C3  1 
HETATM 10082 C C4  . IHP F 2 .   ? 152.936 125.306 86.093  1.00 107.62 ? 1002 IHP B C4  1 
HETATM 10083 C C5  . IHP F 2 .   ? 154.215 126.112 86.120  1.00 107.62 ? 1002 IHP B C5  1 
HETATM 10084 C C6  . IHP F 2 .   ? 154.669 126.605 87.476  1.00 107.62 ? 1002 IHP B C6  1 
HETATM 10085 O O11 . IHP F 2 .   ? 154.473 125.765 89.713  1.00 107.62 ? 1002 IHP B O11 1 
HETATM 10086 P P1  . IHP F 2 .   ? 155.531 126.456 90.732  1.00 107.62 ? 1002 IHP B P1  1 
HETATM 10087 O O21 . IHP F 2 .   ? 155.717 125.379 91.767  1.00 107.62 ? 1002 IHP B O21 1 
HETATM 10088 O O31 . IHP F 2 .   ? 156.803 126.690 89.937  1.00 107.62 ? 1002 IHP B O31 1 
HETATM 10089 O O41 . IHP F 2 .   ? 154.781 127.717 91.180  1.00 107.62 ? 1002 IHP B O41 1 
HETATM 10090 O O12 . IHP F 2 .   ? 151.582 126.739 89.237  1.00 107.62 ? 1002 IHP B O12 1 
HETATM 10091 P P2  . IHP F 2 .   ? 150.887 126.419 90.661  1.00 107.62 ? 1002 IHP B P2  1 
HETATM 10092 O O22 . IHP F 2 .   ? 151.066 127.673 91.498  1.00 107.62 ? 1002 IHP B O22 1 
HETATM 10093 O O32 . IHP F 2 .   ? 151.715 125.306 91.246  1.00 107.62 ? 1002 IHP B O32 1 
HETATM 10094 O O42 . IHP F 2 .   ? 149.472 126.157 90.154  1.00 107.62 ? 1002 IHP B O42 1 
HETATM 10095 O O13 . IHP F 2 .   ? 151.423 127.025 86.707  1.00 107.62 ? 1002 IHP B O13 1 
HETATM 10096 P P3  . IHP F 2 .   ? 149.902 127.444 86.310  1.00 107.62 ? 1002 IHP B P3  1 
HETATM 10097 O O23 . IHP F 2 .   ? 149.735 127.116 84.857  1.00 107.62 ? 1002 IHP B O23 1 
HETATM 10098 O O33 . IHP F 2 .   ? 148.943 126.716 87.234  1.00 107.62 ? 1002 IHP B O33 1 
HETATM 10099 O O43 . IHP F 2 .   ? 149.928 128.926 86.606  1.00 107.62 ? 1002 IHP B O43 1 
HETATM 10100 O O14 . IHP F 2 .   ? 152.499 125.582 84.764  1.00 107.62 ? 1002 IHP B O14 1 
HETATM 10101 P P4  . IHP F 2 .   ? 151.860 124.584 83.694  1.00 107.62 ? 1002 IHP B P4  1 
HETATM 10102 O O24 . IHP F 2 .   ? 152.095 125.346 82.410  1.00 107.62 ? 1002 IHP B O24 1 
HETATM 10103 O O34 . IHP F 2 .   ? 152.708 123.330 83.823  1.00 107.62 ? 1002 IHP B O34 1 
HETATM 10104 O O44 . IHP F 2 .   ? 150.386 124.442 84.071  1.00 107.62 ? 1002 IHP B O44 1 
HETATM 10105 O O15 . IHP F 2 .   ? 155.303 125.406 85.529  1.00 107.62 ? 1002 IHP B O15 1 
HETATM 10106 P P5  . IHP F 2 .   ? 156.263 125.976 84.360  1.00 107.62 ? 1002 IHP B P5  1 
HETATM 10107 O O25 . IHP F 2 .   ? 155.865 127.415 84.084  1.00 107.62 ? 1002 IHP B O25 1 
HETATM 10108 O O35 . IHP F 2 .   ? 155.968 125.060 83.180  1.00 107.62 ? 1002 IHP B O35 1 
HETATM 10109 O O45 . IHP F 2 .   ? 157.574 125.789 85.091  1.00 107.62 ? 1002 IHP B O45 1 
HETATM 10110 O O16 . IHP F 2 .   ? 154.586 127.979 87.197  1.00 107.62 ? 1002 IHP B O16 1 
HETATM 10111 P P6  . IHP F 2 .   ? 155.837 128.942 87.231  1.00 107.62 ? 1002 IHP B P6  1 
HETATM 10112 O O26 . IHP F 2 .   ? 156.248 128.733 88.674  1.00 107.62 ? 1002 IHP B O26 1 
HETATM 10113 O O36 . IHP F 2 .   ? 155.104 130.223 86.809  1.00 107.62 ? 1002 IHP B O36 1 
HETATM 10114 O O46 . IHP F 2 .   ? 156.826 128.357 86.260  1.00 107.62 ? 1002 IHP B O46 1 
# 
