data_9IJU
# 
_entry.id   9IJU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9IJU         pdb_00009iju 10.2210/pdb9iju/pdb 
WWPDB D_1300048961 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'Structure model' 1 1 2025-03-26 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9IJU 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              nxzhang@simm.ac.cn 
_pdbx_contact_author.name_first         Naixia 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4824-5819 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Shi, L.'   1 ? 
'Xu, Z.'    2 ? 
'Chen, X.'  3 ? 
'Xiong, B.' 4 ? 
'Zhang, N.' 5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Med.Chem. 
_citation.journal_id_ASTM           JMCMAR 
_citation.journal_id_CSD            0151 
_citation.journal_id_ISSN           0022-2623 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            68 
_citation.language                  ? 
_citation.page_first                5874 
_citation.page_last                 5890 
_citation.title                     
'Sertraline and Astemizole Enhance the Deubiquitinase Activity of USP7 by Binding to Its Switching Loop Region.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.jmedchem.5c00032 
_citation.pdbx_database_id_PubMed   39999290 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Shi, L.'   1 ? 
primary 'Xu, Z.'    2 ? 
primary 'Chen, X.'  3 ? 
primary 'Meng, Q.'  4 ? 
primary 'Zhou, H.'  5 ? 
primary 'Xiong, B.' 6 ? 
primary 'Zhang, N.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Ubiquitin carboxyl-terminal hydrolase 7'                                      41004.340 4  3.4.19.12 ? ? ? 
2 polymer     man Ubiquitin                                                                      8519.778  4  ?         ? ? ? 
3 non-polymer syn '(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine' 306.230   2  ?         ? ? ? 
4 water       nat water                                                                          18.015    65 ?         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
;Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7
;
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWET
LDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDY
VAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN
YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEV
LQAVTDHDIPQQLVERLQEEKRIEAQKRKERQE
;
;KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWET
LDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDY
VAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN
YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEV
LQAVTDHDIPQQLVERLQEEKRIEAQKRKERQE
;
A,C,E,G ? 
2 'polypeptide(L)' no no MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG 
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG B,D,F,H ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 '(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine' SRE 
4 water                                                                          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   LYS n 
1 2   LYS n 
1 3   HIS n 
1 4   THR n 
1 5   GLY n 
1 6   TYR n 
1 7   VAL n 
1 8   GLY n 
1 9   LEU n 
1 10  LYS n 
1 11  ASN n 
1 12  GLN n 
1 13  GLY n 
1 14  ALA n 
1 15  THR n 
1 16  CYS n 
1 17  TYR n 
1 18  MET n 
1 19  ASN n 
1 20  SER n 
1 21  LEU n 
1 22  LEU n 
1 23  GLN n 
1 24  THR n 
1 25  LEU n 
1 26  PHE n 
1 27  PHE n 
1 28  THR n 
1 29  ASN n 
1 30  GLN n 
1 31  LEU n 
1 32  ARG n 
1 33  LYS n 
1 34  ALA n 
1 35  VAL n 
1 36  TYR n 
1 37  MET n 
1 38  MET n 
1 39  PRO n 
1 40  THR n 
1 41  GLU n 
1 42  GLY n 
1 43  ASP n 
1 44  ASP n 
1 45  SER n 
1 46  SER n 
1 47  LYS n 
1 48  SER n 
1 49  VAL n 
1 50  PRO n 
1 51  LEU n 
1 52  ALA n 
1 53  LEU n 
1 54  GLN n 
1 55  ARG n 
1 56  VAL n 
1 57  PHE n 
1 58  TYR n 
1 59  GLU n 
1 60  LEU n 
1 61  GLN n 
1 62  HIS n 
1 63  SER n 
1 64  ASP n 
1 65  LYS n 
1 66  PRO n 
1 67  VAL n 
1 68  GLY n 
1 69  THR n 
1 70  LYS n 
1 71  LYS n 
1 72  LEU n 
1 73  THR n 
1 74  LYS n 
1 75  SER n 
1 76  PHE n 
1 77  GLY n 
1 78  TRP n 
1 79  GLU n 
1 80  THR n 
1 81  LEU n 
1 82  ASP n 
1 83  SER n 
1 84  PHE n 
1 85  MET n 
1 86  GLN n 
1 87  HIS n 
1 88  ASP n 
1 89  VAL n 
1 90  GLN n 
1 91  GLU n 
1 92  LEU n 
1 93  CYS n 
1 94  ARG n 
1 95  VAL n 
1 96  LEU n 
1 97  LEU n 
1 98  ASP n 
1 99  ASN n 
1 100 VAL n 
1 101 GLU n 
1 102 ASN n 
1 103 LYS n 
1 104 MET n 
1 105 LYS n 
1 106 GLY n 
1 107 THR n 
1 108 CYS n 
1 109 VAL n 
1 110 GLU n 
1 111 GLY n 
1 112 THR n 
1 113 ILE n 
1 114 PRO n 
1 115 LYS n 
1 116 LEU n 
1 117 PHE n 
1 118 ARG n 
1 119 GLY n 
1 120 LYS n 
1 121 MET n 
1 122 VAL n 
1 123 SER n 
1 124 TYR n 
1 125 ILE n 
1 126 GLN n 
1 127 CYS n 
1 128 LYS n 
1 129 GLU n 
1 130 VAL n 
1 131 ASP n 
1 132 TYR n 
1 133 ARG n 
1 134 SER n 
1 135 ASP n 
1 136 ARG n 
1 137 ARG n 
1 138 GLU n 
1 139 ASP n 
1 140 TYR n 
1 141 TYR n 
1 142 ASP n 
1 143 ILE n 
1 144 GLN n 
1 145 LEU n 
1 146 SER n 
1 147 ILE n 
1 148 LYS n 
1 149 GLY n 
1 150 LYS n 
1 151 LYS n 
1 152 ASN n 
1 153 ILE n 
1 154 PHE n 
1 155 GLU n 
1 156 SER n 
1 157 PHE n 
1 158 VAL n 
1 159 ASP n 
1 160 TYR n 
1 161 VAL n 
1 162 ALA n 
1 163 VAL n 
1 164 GLU n 
1 165 GLN n 
1 166 LEU n 
1 167 ASP n 
1 168 GLY n 
1 169 ASP n 
1 170 ASN n 
1 171 LYS n 
1 172 TYR n 
1 173 ASP n 
1 174 ALA n 
1 175 GLY n 
1 176 GLU n 
1 177 HIS n 
1 178 GLY n 
1 179 LEU n 
1 180 GLN n 
1 181 GLU n 
1 182 ALA n 
1 183 GLU n 
1 184 LYS n 
1 185 GLY n 
1 186 VAL n 
1 187 LYS n 
1 188 PHE n 
1 189 LEU n 
1 190 THR n 
1 191 LEU n 
1 192 PRO n 
1 193 PRO n 
1 194 VAL n 
1 195 LEU n 
1 196 HIS n 
1 197 LEU n 
1 198 GLN n 
1 199 LEU n 
1 200 MET n 
1 201 ARG n 
1 202 PHE n 
1 203 MET n 
1 204 TYR n 
1 205 ASP n 
1 206 PRO n 
1 207 GLN n 
1 208 THR n 
1 209 ASP n 
1 210 GLN n 
1 211 ASN n 
1 212 ILE n 
1 213 LYS n 
1 214 ILE n 
1 215 ASN n 
1 216 ASP n 
1 217 ARG n 
1 218 PHE n 
1 219 GLU n 
1 220 PHE n 
1 221 PRO n 
1 222 GLU n 
1 223 GLN n 
1 224 LEU n 
1 225 PRO n 
1 226 LEU n 
1 227 ASP n 
1 228 GLU n 
1 229 PHE n 
1 230 LEU n 
1 231 GLN n 
1 232 LYS n 
1 233 THR n 
1 234 ASP n 
1 235 PRO n 
1 236 LYS n 
1 237 ASP n 
1 238 PRO n 
1 239 ALA n 
1 240 ASN n 
1 241 TYR n 
1 242 ILE n 
1 243 LEU n 
1 244 HIS n 
1 245 ALA n 
1 246 VAL n 
1 247 LEU n 
1 248 VAL n 
1 249 HIS n 
1 250 SER n 
1 251 GLY n 
1 252 ASP n 
1 253 ASN n 
1 254 HIS n 
1 255 GLY n 
1 256 GLY n 
1 257 HIS n 
1 258 TYR n 
1 259 VAL n 
1 260 VAL n 
1 261 TYR n 
1 262 LEU n 
1 263 ASN n 
1 264 PRO n 
1 265 LYS n 
1 266 GLY n 
1 267 ASP n 
1 268 GLY n 
1 269 LYS n 
1 270 TRP n 
1 271 CYS n 
1 272 LYS n 
1 273 PHE n 
1 274 ASP n 
1 275 ASP n 
1 276 ASP n 
1 277 VAL n 
1 278 VAL n 
1 279 SER n 
1 280 ARG n 
1 281 CYS n 
1 282 THR n 
1 283 LYS n 
1 284 GLU n 
1 285 GLU n 
1 286 ALA n 
1 287 ILE n 
1 288 GLU n 
1 289 HIS n 
1 290 ASN n 
1 291 TYR n 
1 292 GLY n 
1 293 GLY n 
1 294 HIS n 
1 295 ASP n 
1 296 ASP n 
1 297 ASP n 
1 298 LEU n 
1 299 SER n 
1 300 VAL n 
1 301 ARG n 
1 302 HIS n 
1 303 CYS n 
1 304 THR n 
1 305 ASN n 
1 306 ALA n 
1 307 TYR n 
1 308 MET n 
1 309 LEU n 
1 310 VAL n 
1 311 TYR n 
1 312 ILE n 
1 313 ARG n 
1 314 GLU n 
1 315 SER n 
1 316 LYS n 
1 317 LEU n 
1 318 SER n 
1 319 GLU n 
1 320 VAL n 
1 321 LEU n 
1 322 GLN n 
1 323 ALA n 
1 324 VAL n 
1 325 THR n 
1 326 ASP n 
1 327 HIS n 
1 328 ASP n 
1 329 ILE n 
1 330 PRO n 
1 331 GLN n 
1 332 GLN n 
1 333 LEU n 
1 334 VAL n 
1 335 GLU n 
1 336 ARG n 
1 337 LEU n 
1 338 GLN n 
1 339 GLU n 
1 340 GLU n 
1 341 LYS n 
1 342 ARG n 
1 343 ILE n 
1 344 GLU n 
1 345 ALA n 
1 346 GLN n 
1 347 LYS n 
1 348 ARG n 
1 349 LYS n 
1 350 GLU n 
1 351 ARG n 
1 352 GLN n 
1 353 GLU n 
2 1   MET n 
2 2   GLN n 
2 3   ILE n 
2 4   PHE n 
2 5   VAL n 
2 6   LYS n 
2 7   THR n 
2 8   LEU n 
2 9   THR n 
2 10  GLY n 
2 11  LYS n 
2 12  THR n 
2 13  ILE n 
2 14  THR n 
2 15  LEU n 
2 16  GLU n 
2 17  VAL n 
2 18  GLU n 
2 19  PRO n 
2 20  SER n 
2 21  ASP n 
2 22  THR n 
2 23  ILE n 
2 24  GLU n 
2 25  ASN n 
2 26  VAL n 
2 27  LYS n 
2 28  ALA n 
2 29  LYS n 
2 30  ILE n 
2 31  GLN n 
2 32  ASP n 
2 33  LYS n 
2 34  GLU n 
2 35  GLY n 
2 36  ILE n 
2 37  PRO n 
2 38  PRO n 
2 39  ASP n 
2 40  GLN n 
2 41  GLN n 
2 42  ARG n 
2 43  LEU n 
2 44  ILE n 
2 45  PHE n 
2 46  ALA n 
2 47  GLY n 
2 48  LYS n 
2 49  GLN n 
2 50  LEU n 
2 51  GLU n 
2 52  ASP n 
2 53  GLY n 
2 54  ARG n 
2 55  THR n 
2 56  LEU n 
2 57  SER n 
2 58  ASP n 
2 59  TYR n 
2 60  ASN n 
2 61  ILE n 
2 62  GLN n 
2 63  LYS n 
2 64  GLU n 
2 65  SER n 
2 66  THR n 
2 67  LEU n 
2 68  HIS n 
2 69  LEU n 
2 70  VAL n 
2 71  LEU n 
2 72  ARG n 
2 73  LEU n 
2 74  ARG n 
2 75  GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 353 human ? 'USP7, HAUSP'           ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 75  human ? 'RPS27A, UBA80, UBCEP1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                        ?          'C3 H7 N O2' 
89.093  
ARG 'L-peptide linking' y ARGININE                                                                       ?          
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                     ?          'C4 H8 N2 O3' 
132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                ?          'C4 H7 N O4' 
133.103 
CYS 'L-peptide linking' y CYSTEINE                                                                       ?          'C3 H7 N O2 S' 
121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                      ?          'C5 H10 N2 O3' 
146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                ?          'C5 H9 N O4' 
147.129 
GLY 'peptide linking'   y GLYCINE                                                                        ?          'C2 H5 N O2' 
75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                      ?          
'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                                                          ?          'H2 O' 18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                     ?          'C6 H13 N O2' 
131.173 
LEU 'L-peptide linking' y LEUCINE                                                                        ?          'C6 H13 N O2' 
131.173 
LYS 'L-peptide linking' y LYSINE                                                                         ?          
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                                     ?          
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                                                  ?          'C9 H11 N O2' 
165.189 
PRO 'L-peptide linking' y PROLINE                                                                        ?          'C5 H9 N O2' 
115.130 
SER 'L-peptide linking' y SERINE                                                                         ?          'C3 H7 N O3' 
105.093 
SRE non-polymer         . '(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine' Sertraline 
'C17 H17 Cl2 N'  306.230 
THR 'L-peptide linking' y THREONINE                                                                      ?          'C4 H9 N O3' 
119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                     ?          
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                                       ?          'C9 H11 N O3' 
181.189 
VAL 'L-peptide linking' y VALINE                                                                         ?          'C5 H11 N O2' 
117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   LYS 1   208 ?   ?   ?   A . n 
A 1 2   LYS 2   209 ?   ?   ?   A . n 
A 1 3   HIS 3   210 210 HIS HIS A . n 
A 1 4   THR 4   211 211 THR THR A . n 
A 1 5   GLY 5   212 212 GLY GLY A . n 
A 1 6   TYR 6   213 213 TYR TYR A . n 
A 1 7   VAL 7   214 214 VAL VAL A . n 
A 1 8   GLY 8   215 215 GLY GLY A . n 
A 1 9   LEU 9   216 216 LEU LEU A . n 
A 1 10  LYS 10  217 217 LYS LYS A . n 
A 1 11  ASN 11  218 218 ASN ASN A . n 
A 1 12  GLN 12  219 219 GLN GLN A . n 
A 1 13  GLY 13  220 220 GLY GLY A . n 
A 1 14  ALA 14  221 221 ALA ALA A . n 
A 1 15  THR 15  222 222 THR THR A . n 
A 1 16  CYS 16  223 223 CYS CYS A . n 
A 1 17  TYR 17  224 224 TYR TYR A . n 
A 1 18  MET 18  225 225 MET MET A . n 
A 1 19  ASN 19  226 226 ASN ASN A . n 
A 1 20  SER 20  227 227 SER SER A . n 
A 1 21  LEU 21  228 228 LEU LEU A . n 
A 1 22  LEU 22  229 229 LEU LEU A . n 
A 1 23  GLN 23  230 230 GLN GLN A . n 
A 1 24  THR 24  231 231 THR THR A . n 
A 1 25  LEU 25  232 232 LEU LEU A . n 
A 1 26  PHE 26  233 233 PHE PHE A . n 
A 1 27  PHE 27  234 234 PHE PHE A . n 
A 1 28  THR 28  235 235 THR THR A . n 
A 1 29  ASN 29  236 236 ASN ASN A . n 
A 1 30  GLN 30  237 237 GLN GLN A . n 
A 1 31  LEU 31  238 238 LEU LEU A . n 
A 1 32  ARG 32  239 239 ARG ARG A . n 
A 1 33  LYS 33  240 240 LYS LYS A . n 
A 1 34  ALA 34  241 241 ALA ALA A . n 
A 1 35  VAL 35  242 242 VAL VAL A . n 
A 1 36  TYR 36  243 243 TYR TYR A . n 
A 1 37  MET 37  244 244 MET MET A . n 
A 1 38  MET 38  245 245 MET MET A . n 
A 1 39  PRO 39  246 246 PRO PRO A . n 
A 1 40  THR 40  247 247 THR THR A . n 
A 1 41  GLU 41  248 248 GLU GLU A . n 
A 1 42  GLY 42  249 ?   ?   ?   A . n 
A 1 43  ASP 43  250 250 ASP ASP A . n 
A 1 44  ASP 44  251 251 ASP ASP A . n 
A 1 45  SER 45  252 252 SER SER A . n 
A 1 46  SER 46  253 253 SER SER A . n 
A 1 47  LYS 47  254 254 LYS LYS A . n 
A 1 48  SER 48  255 255 SER SER A . n 
A 1 49  VAL 49  256 256 VAL VAL A . n 
A 1 50  PRO 50  257 257 PRO PRO A . n 
A 1 51  LEU 51  258 258 LEU LEU A . n 
A 1 52  ALA 52  259 259 ALA ALA A . n 
A 1 53  LEU 53  260 260 LEU LEU A . n 
A 1 54  GLN 54  261 261 GLN GLN A . n 
A 1 55  ARG 55  262 262 ARG ARG A . n 
A 1 56  VAL 56  263 263 VAL VAL A . n 
A 1 57  PHE 57  264 264 PHE PHE A . n 
A 1 58  TYR 58  265 265 TYR TYR A . n 
A 1 59  GLU 59  266 266 GLU GLU A . n 
A 1 60  LEU 60  267 267 LEU LEU A . n 
A 1 61  GLN 61  268 268 GLN GLN A . n 
A 1 62  HIS 62  269 269 HIS HIS A . n 
A 1 63  SER 63  270 270 SER SER A . n 
A 1 64  ASP 64  271 271 ASP ASP A . n 
A 1 65  LYS 65  272 272 LYS LYS A . n 
A 1 66  PRO 66  273 273 PRO PRO A . n 
A 1 67  VAL 67  274 274 VAL VAL A . n 
A 1 68  GLY 68  275 275 GLY GLY A . n 
A 1 69  THR 69  276 276 THR THR A . n 
A 1 70  LYS 70  277 277 LYS LYS A . n 
A 1 71  LYS 71  278 278 LYS LYS A . n 
A 1 72  LEU 72  279 279 LEU LEU A . n 
A 1 73  THR 73  280 280 THR THR A . n 
A 1 74  LYS 74  281 281 LYS LYS A . n 
A 1 75  SER 75  282 282 SER SER A . n 
A 1 76  PHE 76  283 283 PHE PHE A . n 
A 1 77  GLY 77  284 284 GLY GLY A . n 
A 1 78  TRP 78  285 285 TRP TRP A . n 
A 1 79  GLU 79  286 286 GLU GLU A . n 
A 1 80  THR 80  287 287 THR THR A . n 
A 1 81  LEU 81  288 288 LEU LEU A . n 
A 1 82  ASP 82  289 289 ASP ASP A . n 
A 1 83  SER 83  290 290 SER SER A . n 
A 1 84  PHE 84  291 291 PHE PHE A . n 
A 1 85  MET 85  292 292 MET MET A . n 
A 1 86  GLN 86  293 293 GLN GLN A . n 
A 1 87  HIS 87  294 294 HIS HIS A . n 
A 1 88  ASP 88  295 295 ASP ASP A . n 
A 1 89  VAL 89  296 296 VAL VAL A . n 
A 1 90  GLN 90  297 297 GLN GLN A . n 
A 1 91  GLU 91  298 298 GLU GLU A . n 
A 1 92  LEU 92  299 299 LEU LEU A . n 
A 1 93  CYS 93  300 300 CYS CYS A . n 
A 1 94  ARG 94  301 301 ARG ARG A . n 
A 1 95  VAL 95  302 302 VAL VAL A . n 
A 1 96  LEU 96  303 303 LEU LEU A . n 
A 1 97  LEU 97  304 304 LEU LEU A . n 
A 1 98  ASP 98  305 305 ASP ASP A . n 
A 1 99  ASN 99  306 306 ASN ASN A . n 
A 1 100 VAL 100 307 307 VAL VAL A . n 
A 1 101 GLU 101 308 308 GLU GLU A . n 
A 1 102 ASN 102 309 309 ASN ASN A . n 
A 1 103 LYS 103 310 310 LYS LYS A . n 
A 1 104 MET 104 311 311 MET MET A . n 
A 1 105 LYS 105 312 312 LYS LYS A . n 
A 1 106 GLY 106 313 313 GLY GLY A . n 
A 1 107 THR 107 314 314 THR THR A . n 
A 1 108 CYS 108 315 315 CYS CYS A . n 
A 1 109 VAL 109 316 316 VAL VAL A . n 
A 1 110 GLU 110 317 317 GLU GLU A . n 
A 1 111 GLY 111 318 318 GLY GLY A . n 
A 1 112 THR 112 319 319 THR THR A . n 
A 1 113 ILE 113 320 320 ILE ILE A . n 
A 1 114 PRO 114 321 321 PRO PRO A . n 
A 1 115 LYS 115 322 322 LYS LYS A . n 
A 1 116 LEU 116 323 323 LEU LEU A . n 
A 1 117 PHE 117 324 324 PHE PHE A . n 
A 1 118 ARG 118 325 325 ARG ARG A . n 
A 1 119 GLY 119 326 326 GLY GLY A . n 
A 1 120 LYS 120 327 327 LYS LYS A . n 
A 1 121 MET 121 328 328 MET MET A . n 
A 1 122 VAL 122 329 329 VAL VAL A . n 
A 1 123 SER 123 330 330 SER SER A . n 
A 1 124 TYR 124 331 331 TYR TYR A . n 
A 1 125 ILE 125 332 332 ILE ILE A . n 
A 1 126 GLN 126 333 333 GLN GLN A . n 
A 1 127 CYS 127 334 334 CYS CYS A . n 
A 1 128 LYS 128 335 335 LYS LYS A . n 
A 1 129 GLU 129 336 336 GLU GLU A . n 
A 1 130 VAL 130 337 337 VAL VAL A . n 
A 1 131 ASP 131 338 338 ASP ASP A . n 
A 1 132 TYR 132 339 339 TYR TYR A . n 
A 1 133 ARG 133 340 340 ARG ARG A . n 
A 1 134 SER 134 341 341 SER SER A . n 
A 1 135 ASP 135 342 342 ASP ASP A . n 
A 1 136 ARG 136 343 343 ARG ARG A . n 
A 1 137 ARG 137 344 344 ARG ARG A . n 
A 1 138 GLU 138 345 345 GLU GLU A . n 
A 1 139 ASP 139 346 346 ASP ASP A . n 
A 1 140 TYR 140 347 347 TYR TYR A . n 
A 1 141 TYR 141 348 348 TYR TYR A . n 
A 1 142 ASP 142 349 349 ASP ASP A . n 
A 1 143 ILE 143 350 350 ILE ILE A . n 
A 1 144 GLN 144 351 351 GLN GLN A . n 
A 1 145 LEU 145 352 352 LEU LEU A . n 
A 1 146 SER 146 353 353 SER SER A . n 
A 1 147 ILE 147 354 354 ILE ILE A . n 
A 1 148 LYS 148 355 355 LYS LYS A . n 
A 1 149 GLY 149 356 356 GLY GLY A . n 
A 1 150 LYS 150 357 357 LYS LYS A . n 
A 1 151 LYS 151 358 358 LYS LYS A . n 
A 1 152 ASN 152 359 359 ASN ASN A . n 
A 1 153 ILE 153 360 360 ILE ILE A . n 
A 1 154 PHE 154 361 361 PHE PHE A . n 
A 1 155 GLU 155 362 362 GLU GLU A . n 
A 1 156 SER 156 363 363 SER SER A . n 
A 1 157 PHE 157 364 364 PHE PHE A . n 
A 1 158 VAL 158 365 365 VAL VAL A . n 
A 1 159 ASP 159 366 366 ASP ASP A . n 
A 1 160 TYR 160 367 367 TYR TYR A . n 
A 1 161 VAL 161 368 368 VAL VAL A . n 
A 1 162 ALA 162 369 369 ALA ALA A . n 
A 1 163 VAL 163 370 370 VAL VAL A . n 
A 1 164 GLU 164 371 371 GLU GLU A . n 
A 1 165 GLN 165 372 372 GLN GLN A . n 
A 1 166 LEU 166 373 373 LEU LEU A . n 
A 1 167 ASP 167 374 374 ASP ASP A . n 
A 1 168 GLY 168 375 375 GLY GLY A . n 
A 1 169 ASP 169 376 376 ASP ASP A . n 
A 1 170 ASN 170 377 377 ASN ASN A . n 
A 1 171 LYS 171 378 378 LYS LYS A . n 
A 1 172 TYR 172 379 379 TYR TYR A . n 
A 1 173 ASP 173 380 380 ASP ASP A . n 
A 1 174 ALA 174 381 381 ALA ALA A . n 
A 1 175 GLY 175 382 382 GLY GLY A . n 
A 1 176 GLU 176 383 383 GLU GLU A . n 
A 1 177 HIS 177 384 384 HIS HIS A . n 
A 1 178 GLY 178 385 385 GLY GLY A . n 
A 1 179 LEU 179 386 386 LEU LEU A . n 
A 1 180 GLN 180 387 387 GLN GLN A . n 
A 1 181 GLU 181 388 388 GLU GLU A . n 
A 1 182 ALA 182 389 389 ALA ALA A . n 
A 1 183 GLU 183 390 390 GLU GLU A . n 
A 1 184 LYS 184 391 391 LYS LYS A . n 
A 1 185 GLY 185 392 392 GLY GLY A . n 
A 1 186 VAL 186 393 393 VAL VAL A . n 
A 1 187 LYS 187 394 394 LYS LYS A . n 
A 1 188 PHE 188 395 395 PHE PHE A . n 
A 1 189 LEU 189 396 396 LEU LEU A . n 
A 1 190 THR 190 397 397 THR THR A . n 
A 1 191 LEU 191 398 398 LEU LEU A . n 
A 1 192 PRO 192 399 399 PRO PRO A . n 
A 1 193 PRO 193 400 400 PRO PRO A . n 
A 1 194 VAL 194 401 401 VAL VAL A . n 
A 1 195 LEU 195 402 402 LEU LEU A . n 
A 1 196 HIS 196 403 403 HIS HIS A . n 
A 1 197 LEU 197 404 404 LEU LEU A . n 
A 1 198 GLN 198 405 405 GLN GLN A . n 
A 1 199 LEU 199 406 406 LEU LEU A . n 
A 1 200 MET 200 407 407 MET MET A . n 
A 1 201 ARG 201 408 408 ARG ARG A . n 
A 1 202 PHE 202 409 409 PHE PHE A . n 
A 1 203 MET 203 410 410 MET MET A . n 
A 1 204 TYR 204 411 411 TYR TYR A . n 
A 1 205 ASP 205 412 ?   ?   ?   A . n 
A 1 206 PRO 206 413 ?   ?   ?   A . n 
A 1 207 GLN 207 414 ?   ?   ?   A . n 
A 1 208 THR 208 415 415 THR THR A . n 
A 1 209 ASP 209 416 416 ASP ASP A . n 
A 1 210 GLN 210 417 417 GLN GLN A . n 
A 1 211 ASN 211 418 418 ASN ASN A . n 
A 1 212 ILE 212 419 419 ILE ILE A . n 
A 1 213 LYS 213 420 420 LYS LYS A . n 
A 1 214 ILE 214 421 421 ILE ILE A . n 
A 1 215 ASN 215 422 422 ASN ASN A . n 
A 1 216 ASP 216 423 423 ASP ASP A . n 
A 1 217 ARG 217 424 424 ARG ARG A . n 
A 1 218 PHE 218 425 425 PHE PHE A . n 
A 1 219 GLU 219 426 426 GLU GLU A . n 
A 1 220 PHE 220 427 427 PHE PHE A . n 
A 1 221 PRO 221 428 428 PRO PRO A . n 
A 1 222 GLU 222 429 429 GLU GLU A . n 
A 1 223 GLN 223 430 430 GLN GLN A . n 
A 1 224 LEU 224 431 431 LEU LEU A . n 
A 1 225 PRO 225 432 432 PRO PRO A . n 
A 1 226 LEU 226 433 433 LEU LEU A . n 
A 1 227 ASP 227 434 434 ASP ASP A . n 
A 1 228 GLU 228 435 435 GLU GLU A . n 
A 1 229 PHE 229 436 436 PHE PHE A . n 
A 1 230 LEU 230 437 437 LEU LEU A . n 
A 1 231 GLN 231 438 438 GLN GLN A . n 
A 1 232 LYS 232 439 439 LYS LYS A . n 
A 1 233 THR 233 440 440 THR THR A . n 
A 1 234 ASP 234 441 441 ASP ASP A . n 
A 1 235 PRO 235 442 442 PRO PRO A . n 
A 1 236 LYS 236 443 443 LYS LYS A . n 
A 1 237 ASP 237 444 444 ASP ASP A . n 
A 1 238 PRO 238 445 445 PRO PRO A . n 
A 1 239 ALA 239 446 446 ALA ALA A . n 
A 1 240 ASN 240 447 447 ASN ASN A . n 
A 1 241 TYR 241 448 448 TYR TYR A . n 
A 1 242 ILE 242 449 449 ILE ILE A . n 
A 1 243 LEU 243 450 450 LEU LEU A . n 
A 1 244 HIS 244 451 451 HIS HIS A . n 
A 1 245 ALA 245 452 452 ALA ALA A . n 
A 1 246 VAL 246 453 453 VAL VAL A . n 
A 1 247 LEU 247 454 454 LEU LEU A . n 
A 1 248 VAL 248 455 455 VAL VAL A . n 
A 1 249 HIS 249 456 456 HIS HIS A . n 
A 1 250 SER 250 457 457 SER SER A . n 
A 1 251 GLY 251 458 458 GLY GLY A . n 
A 1 252 ASP 252 459 459 ASP ASP A . n 
A 1 253 ASN 253 460 460 ASN ASN A . n 
A 1 254 HIS 254 461 461 HIS HIS A . n 
A 1 255 GLY 255 462 462 GLY GLY A . n 
A 1 256 GLY 256 463 463 GLY GLY A . n 
A 1 257 HIS 257 464 464 HIS HIS A . n 
A 1 258 TYR 258 465 465 TYR TYR A . n 
A 1 259 VAL 259 466 466 VAL VAL A . n 
A 1 260 VAL 260 467 467 VAL VAL A . n 
A 1 261 TYR 261 468 468 TYR TYR A . n 
A 1 262 LEU 262 469 469 LEU LEU A . n 
A 1 263 ASN 263 470 470 ASN ASN A . n 
A 1 264 PRO 264 471 471 PRO PRO A . n 
A 1 265 LYS 265 472 472 LYS LYS A . n 
A 1 266 GLY 266 473 473 GLY GLY A . n 
A 1 267 ASP 267 474 474 ASP ASP A . n 
A 1 268 GLY 268 475 475 GLY GLY A . n 
A 1 269 LYS 269 476 476 LYS LYS A . n 
A 1 270 TRP 270 477 477 TRP TRP A . n 
A 1 271 CYS 271 478 478 CYS CYS A . n 
A 1 272 LYS 272 479 479 LYS LYS A . n 
A 1 273 PHE 273 480 480 PHE PHE A . n 
A 1 274 ASP 274 481 481 ASP ASP A . n 
A 1 275 ASP 275 482 482 ASP ASP A . n 
A 1 276 ASP 276 483 483 ASP ASP A . n 
A 1 277 VAL 277 484 484 VAL VAL A . n 
A 1 278 VAL 278 485 485 VAL VAL A . n 
A 1 279 SER 279 486 486 SER SER A . n 
A 1 280 ARG 280 487 487 ARG ARG A . n 
A 1 281 CYS 281 488 488 CYS CYS A . n 
A 1 282 THR 282 489 489 THR THR A . n 
A 1 283 LYS 283 490 490 LYS LYS A . n 
A 1 284 GLU 284 491 491 GLU GLU A . n 
A 1 285 GLU 285 492 492 GLU GLU A . n 
A 1 286 ALA 286 493 493 ALA ALA A . n 
A 1 287 ILE 287 494 494 ILE ILE A . n 
A 1 288 GLU 288 495 495 GLU GLU A . n 
A 1 289 HIS 289 496 496 HIS HIS A . n 
A 1 290 ASN 290 497 497 ASN ASN A . n 
A 1 291 TYR 291 498 498 TYR TYR A . n 
A 1 292 GLY 292 499 499 GLY GLY A . n 
A 1 293 GLY 293 500 500 GLY GLY A . n 
A 1 294 HIS 294 501 ?   ?   ?   A . n 
A 1 295 ASP 295 502 ?   ?   ?   A . n 
A 1 296 ASP 296 503 ?   ?   ?   A . n 
A 1 297 ASP 297 504 ?   ?   ?   A . n 
A 1 298 LEU 298 505 ?   ?   ?   A . n 
A 1 299 SER 299 506 ?   ?   ?   A . n 
A 1 300 VAL 300 507 ?   ?   ?   A . n 
A 1 301 ARG 301 508 ?   ?   ?   A . n 
A 1 302 HIS 302 509 ?   ?   ?   A . n 
A 1 303 CYS 303 510 510 CYS CYS A . n 
A 1 304 THR 304 511 511 THR THR A . n 
A 1 305 ASN 305 512 512 ASN ASN A . n 
A 1 306 ALA 306 513 513 ALA ALA A . n 
A 1 307 TYR 307 514 514 TYR TYR A . n 
A 1 308 MET 308 515 515 MET MET A . n 
A 1 309 LEU 309 516 516 LEU LEU A . n 
A 1 310 VAL 310 517 517 VAL VAL A . n 
A 1 311 TYR 311 518 518 TYR TYR A . n 
A 1 312 ILE 312 519 519 ILE ILE A . n 
A 1 313 ARG 313 520 520 ARG ARG A . n 
A 1 314 GLU 314 521 521 GLU GLU A . n 
A 1 315 SER 315 522 522 SER SER A . n 
A 1 316 LYS 316 523 523 LYS LYS A . n 
A 1 317 LEU 317 524 524 LEU LEU A . n 
A 1 318 SER 318 525 525 SER SER A . n 
A 1 319 GLU 319 526 526 GLU GLU A . n 
A 1 320 VAL 320 527 527 VAL VAL A . n 
A 1 321 LEU 321 528 528 LEU LEU A . n 
A 1 322 GLN 322 529 529 GLN GLN A . n 
A 1 323 ALA 323 530 530 ALA ALA A . n 
A 1 324 VAL 324 531 531 VAL VAL A . n 
A 1 325 THR 325 532 532 THR THR A . n 
A 1 326 ASP 326 533 533 ASP ASP A . n 
A 1 327 HIS 327 534 534 HIS HIS A . n 
A 1 328 ASP 328 535 535 ASP ASP A . n 
A 1 329 ILE 329 536 536 ILE ILE A . n 
A 1 330 PRO 330 537 537 PRO PRO A . n 
A 1 331 GLN 331 538 538 GLN GLN A . n 
A 1 332 GLN 332 539 539 GLN GLN A . n 
A 1 333 LEU 333 540 540 LEU LEU A . n 
A 1 334 VAL 334 541 541 VAL VAL A . n 
A 1 335 GLU 335 542 542 GLU GLU A . n 
A 1 336 ARG 336 543 543 ARG ARG A . n 
A 1 337 LEU 337 544 544 LEU LEU A . n 
A 1 338 GLN 338 545 545 GLN GLN A . n 
A 1 339 GLU 339 546 546 GLU GLU A . n 
A 1 340 GLU 340 547 547 GLU GLU A . n 
A 1 341 LYS 341 548 548 LYS LYS A . n 
A 1 342 ARG 342 549 ?   ?   ?   A . n 
A 1 343 ILE 343 550 ?   ?   ?   A . n 
A 1 344 GLU 344 551 ?   ?   ?   A . n 
A 1 345 ALA 345 552 ?   ?   ?   A . n 
A 1 346 GLN 346 553 ?   ?   ?   A . n 
A 1 347 LYS 347 554 ?   ?   ?   A . n 
A 1 348 ARG 348 555 ?   ?   ?   A . n 
A 1 349 LYS 349 556 ?   ?   ?   A . n 
A 1 350 GLU 350 557 ?   ?   ?   A . n 
A 1 351 ARG 351 558 ?   ?   ?   A . n 
A 1 352 GLN 352 559 ?   ?   ?   A . n 
A 1 353 GLU 353 560 ?   ?   ?   A . n 
B 2 1   MET 1   1   1   MET MET B . n 
B 2 2   GLN 2   2   2   GLN GLN B . n 
B 2 3   ILE 3   3   3   ILE ILE B . n 
B 2 4   PHE 4   4   4   PHE PHE B . n 
B 2 5   VAL 5   5   5   VAL VAL B . n 
B 2 6   LYS 6   6   6   LYS LYS B . n 
B 2 7   THR 7   7   7   THR THR B . n 
B 2 8   LEU 8   8   8   LEU LEU B . n 
B 2 9   THR 9   9   9   THR THR B . n 
B 2 10  GLY 10  10  10  GLY GLY B . n 
B 2 11  LYS 11  11  11  LYS LYS B . n 
B 2 12  THR 12  12  12  THR THR B . n 
B 2 13  ILE 13  13  13  ILE ILE B . n 
B 2 14  THR 14  14  14  THR THR B . n 
B 2 15  LEU 15  15  15  LEU LEU B . n 
B 2 16  GLU 16  16  16  GLU GLU B . n 
B 2 17  VAL 17  17  17  VAL VAL B . n 
B 2 18  GLU 18  18  18  GLU GLU B . n 
B 2 19  PRO 19  19  19  PRO PRO B . n 
B 2 20  SER 20  20  20  SER SER B . n 
B 2 21  ASP 21  21  21  ASP ASP B . n 
B 2 22  THR 22  22  22  THR THR B . n 
B 2 23  ILE 23  23  23  ILE ILE B . n 
B 2 24  GLU 24  24  24  GLU GLU B . n 
B 2 25  ASN 25  25  25  ASN ASN B . n 
B 2 26  VAL 26  26  26  VAL VAL B . n 
B 2 27  LYS 27  27  27  LYS LYS B . n 
B 2 28  ALA 28  28  28  ALA ALA B . n 
B 2 29  LYS 29  29  29  LYS LYS B . n 
B 2 30  ILE 30  30  30  ILE ILE B . n 
B 2 31  GLN 31  31  31  GLN GLN B . n 
B 2 32  ASP 32  32  32  ASP ASP B . n 
B 2 33  LYS 33  33  33  LYS LYS B . n 
B 2 34  GLU 34  34  34  GLU GLU B . n 
B 2 35  GLY 35  35  35  GLY GLY B . n 
B 2 36  ILE 36  36  36  ILE ILE B . n 
B 2 37  PRO 37  37  37  PRO PRO B . n 
B 2 38  PRO 38  38  38  PRO PRO B . n 
B 2 39  ASP 39  39  39  ASP ASP B . n 
B 2 40  GLN 40  40  40  GLN GLN B . n 
B 2 41  GLN 41  41  41  GLN GLN B . n 
B 2 42  ARG 42  42  42  ARG ARG B . n 
B 2 43  LEU 43  43  43  LEU LEU B . n 
B 2 44  ILE 44  44  44  ILE ILE B . n 
B 2 45  PHE 45  45  45  PHE PHE B . n 
B 2 46  ALA 46  46  46  ALA ALA B . n 
B 2 47  GLY 47  47  47  GLY GLY B . n 
B 2 48  LYS 48  48  48  LYS LYS B . n 
B 2 49  GLN 49  49  49  GLN GLN B . n 
B 2 50  LEU 50  50  50  LEU LEU B . n 
B 2 51  GLU 51  51  51  GLU GLU B . n 
B 2 52  ASP 52  52  52  ASP ASP B . n 
B 2 53  GLY 53  53  53  GLY GLY B . n 
B 2 54  ARG 54  54  54  ARG ARG B . n 
B 2 55  THR 55  55  55  THR THR B . n 
B 2 56  LEU 56  56  56  LEU LEU B . n 
B 2 57  SER 57  57  57  SER SER B . n 
B 2 58  ASP 58  58  58  ASP ASP B . n 
B 2 59  TYR 59  59  59  TYR TYR B . n 
B 2 60  ASN 60  60  60  ASN ASN B . n 
B 2 61  ILE 61  61  61  ILE ILE B . n 
B 2 62  GLN 62  62  62  GLN GLN B . n 
B 2 63  LYS 63  63  63  LYS LYS B . n 
B 2 64  GLU 64  64  64  GLU GLU B . n 
B 2 65  SER 65  65  65  SER SER B . n 
B 2 66  THR 66  66  66  THR THR B . n 
B 2 67  LEU 67  67  67  LEU LEU B . n 
B 2 68  HIS 68  68  68  HIS HIS B . n 
B 2 69  LEU 69  69  69  LEU LEU B . n 
B 2 70  VAL 70  70  70  VAL VAL B . n 
B 2 71  LEU 71  71  71  LEU LEU B . n 
B 2 72  ARG 72  72  72  ARG ARG B . n 
B 2 73  LEU 73  73  73  LEU LEU B . n 
B 2 74  ARG 74  74  74  ARG ARG B . n 
B 2 75  GLY 75  75  75  GLY GLY B . n 
C 1 1   LYS 1   208 ?   ?   ?   C . n 
C 1 2   LYS 2   209 ?   ?   ?   C . n 
C 1 3   HIS 3   210 ?   ?   ?   C . n 
C 1 4   THR 4   211 211 THR THR C . n 
C 1 5   GLY 5   212 212 GLY GLY C . n 
C 1 6   TYR 6   213 213 TYR TYR C . n 
C 1 7   VAL 7   214 214 VAL VAL C . n 
C 1 8   GLY 8   215 215 GLY GLY C . n 
C 1 9   LEU 9   216 216 LEU LEU C . n 
C 1 10  LYS 10  217 217 LYS LYS C . n 
C 1 11  ASN 11  218 218 ASN ASN C . n 
C 1 12  GLN 12  219 219 GLN GLN C . n 
C 1 13  GLY 13  220 220 GLY GLY C . n 
C 1 14  ALA 14  221 221 ALA ALA C . n 
C 1 15  THR 15  222 222 THR THR C . n 
C 1 16  CYS 16  223 223 CYS CYS C . n 
C 1 17  TYR 17  224 224 TYR TYR C . n 
C 1 18  MET 18  225 225 MET MET C . n 
C 1 19  ASN 19  226 226 ASN ASN C . n 
C 1 20  SER 20  227 227 SER SER C . n 
C 1 21  LEU 21  228 228 LEU LEU C . n 
C 1 22  LEU 22  229 229 LEU LEU C . n 
C 1 23  GLN 23  230 230 GLN GLN C . n 
C 1 24  THR 24  231 231 THR THR C . n 
C 1 25  LEU 25  232 232 LEU LEU C . n 
C 1 26  PHE 26  233 233 PHE PHE C . n 
C 1 27  PHE 27  234 234 PHE PHE C . n 
C 1 28  THR 28  235 235 THR THR C . n 
C 1 29  ASN 29  236 236 ASN ASN C . n 
C 1 30  GLN 30  237 237 GLN GLN C . n 
C 1 31  LEU 31  238 238 LEU LEU C . n 
C 1 32  ARG 32  239 239 ARG ARG C . n 
C 1 33  LYS 33  240 240 LYS LYS C . n 
C 1 34  ALA 34  241 241 ALA ALA C . n 
C 1 35  VAL 35  242 242 VAL VAL C . n 
C 1 36  TYR 36  243 243 TYR TYR C . n 
C 1 37  MET 37  244 244 MET MET C . n 
C 1 38  MET 38  245 245 MET MET C . n 
C 1 39  PRO 39  246 246 PRO PRO C . n 
C 1 40  THR 40  247 247 THR THR C . n 
C 1 41  GLU 41  248 ?   ?   ?   C . n 
C 1 42  GLY 42  249 ?   ?   ?   C . n 
C 1 43  ASP 43  250 ?   ?   ?   C . n 
C 1 44  ASP 44  251 ?   ?   ?   C . n 
C 1 45  SER 45  252 ?   ?   ?   C . n 
C 1 46  SER 46  253 253 SER SER C . n 
C 1 47  LYS 47  254 254 LYS LYS C . n 
C 1 48  SER 48  255 255 SER SER C . n 
C 1 49  VAL 49  256 256 VAL VAL C . n 
C 1 50  PRO 50  257 257 PRO PRO C . n 
C 1 51  LEU 51  258 258 LEU LEU C . n 
C 1 52  ALA 52  259 259 ALA ALA C . n 
C 1 53  LEU 53  260 260 LEU LEU C . n 
C 1 54  GLN 54  261 261 GLN GLN C . n 
C 1 55  ARG 55  262 262 ARG ARG C . n 
C 1 56  VAL 56  263 263 VAL VAL C . n 
C 1 57  PHE 57  264 264 PHE PHE C . n 
C 1 58  TYR 58  265 265 TYR TYR C . n 
C 1 59  GLU 59  266 266 GLU GLU C . n 
C 1 60  LEU 60  267 267 LEU LEU C . n 
C 1 61  GLN 61  268 268 GLN GLN C . n 
C 1 62  HIS 62  269 269 HIS HIS C . n 
C 1 63  SER 63  270 270 SER SER C . n 
C 1 64  ASP 64  271 271 ASP ASP C . n 
C 1 65  LYS 65  272 272 LYS LYS C . n 
C 1 66  PRO 66  273 273 PRO PRO C . n 
C 1 67  VAL 67  274 274 VAL VAL C . n 
C 1 68  GLY 68  275 275 GLY GLY C . n 
C 1 69  THR 69  276 276 THR THR C . n 
C 1 70  LYS 70  277 277 LYS LYS C . n 
C 1 71  LYS 71  278 278 LYS LYS C . n 
C 1 72  LEU 72  279 279 LEU LEU C . n 
C 1 73  THR 73  280 280 THR THR C . n 
C 1 74  LYS 74  281 281 LYS LYS C . n 
C 1 75  SER 75  282 282 SER SER C . n 
C 1 76  PHE 76  283 283 PHE PHE C . n 
C 1 77  GLY 77  284 284 GLY GLY C . n 
C 1 78  TRP 78  285 285 TRP TRP C . n 
C 1 79  GLU 79  286 286 GLU GLU C . n 
C 1 80  THR 80  287 287 THR THR C . n 
C 1 81  LEU 81  288 288 LEU LEU C . n 
C 1 82  ASP 82  289 289 ASP ASP C . n 
C 1 83  SER 83  290 290 SER SER C . n 
C 1 84  PHE 84  291 291 PHE PHE C . n 
C 1 85  MET 85  292 292 MET MET C . n 
C 1 86  GLN 86  293 293 GLN GLN C . n 
C 1 87  HIS 87  294 294 HIS HIS C . n 
C 1 88  ASP 88  295 295 ASP ASP C . n 
C 1 89  VAL 89  296 296 VAL VAL C . n 
C 1 90  GLN 90  297 297 GLN GLN C . n 
C 1 91  GLU 91  298 298 GLU GLU C . n 
C 1 92  LEU 92  299 299 LEU LEU C . n 
C 1 93  CYS 93  300 300 CYS CYS C . n 
C 1 94  ARG 94  301 301 ARG ARG C . n 
C 1 95  VAL 95  302 302 VAL VAL C . n 
C 1 96  LEU 96  303 303 LEU LEU C . n 
C 1 97  LEU 97  304 304 LEU LEU C . n 
C 1 98  ASP 98  305 305 ASP ASP C . n 
C 1 99  ASN 99  306 306 ASN ASN C . n 
C 1 100 VAL 100 307 307 VAL VAL C . n 
C 1 101 GLU 101 308 308 GLU GLU C . n 
C 1 102 ASN 102 309 309 ASN ASN C . n 
C 1 103 LYS 103 310 310 LYS LYS C . n 
C 1 104 MET 104 311 311 MET MET C . n 
C 1 105 LYS 105 312 312 LYS LYS C . n 
C 1 106 GLY 106 313 313 GLY GLY C . n 
C 1 107 THR 107 314 314 THR THR C . n 
C 1 108 CYS 108 315 315 CYS CYS C . n 
C 1 109 VAL 109 316 316 VAL VAL C . n 
C 1 110 GLU 110 317 317 GLU GLU C . n 
C 1 111 GLY 111 318 318 GLY GLY C . n 
C 1 112 THR 112 319 319 THR THR C . n 
C 1 113 ILE 113 320 320 ILE ILE C . n 
C 1 114 PRO 114 321 321 PRO PRO C . n 
C 1 115 LYS 115 322 322 LYS LYS C . n 
C 1 116 LEU 116 323 323 LEU LEU C . n 
C 1 117 PHE 117 324 324 PHE PHE C . n 
C 1 118 ARG 118 325 325 ARG ARG C . n 
C 1 119 GLY 119 326 326 GLY GLY C . n 
C 1 120 LYS 120 327 327 LYS LYS C . n 
C 1 121 MET 121 328 328 MET MET C . n 
C 1 122 VAL 122 329 329 VAL VAL C . n 
C 1 123 SER 123 330 330 SER SER C . n 
C 1 124 TYR 124 331 331 TYR TYR C . n 
C 1 125 ILE 125 332 332 ILE ILE C . n 
C 1 126 GLN 126 333 333 GLN GLN C . n 
C 1 127 CYS 127 334 334 CYS CYS C . n 
C 1 128 LYS 128 335 335 LYS LYS C . n 
C 1 129 GLU 129 336 336 GLU GLU C . n 
C 1 130 VAL 130 337 337 VAL VAL C . n 
C 1 131 ASP 131 338 338 ASP ASP C . n 
C 1 132 TYR 132 339 339 TYR TYR C . n 
C 1 133 ARG 133 340 340 ARG ARG C . n 
C 1 134 SER 134 341 341 SER SER C . n 
C 1 135 ASP 135 342 342 ASP ASP C . n 
C 1 136 ARG 136 343 343 ARG ARG C . n 
C 1 137 ARG 137 344 344 ARG ARG C . n 
C 1 138 GLU 138 345 345 GLU GLU C . n 
C 1 139 ASP 139 346 346 ASP ASP C . n 
C 1 140 TYR 140 347 347 TYR TYR C . n 
C 1 141 TYR 141 348 348 TYR TYR C . n 
C 1 142 ASP 142 349 349 ASP ASP C . n 
C 1 143 ILE 143 350 350 ILE ILE C . n 
C 1 144 GLN 144 351 351 GLN GLN C . n 
C 1 145 LEU 145 352 352 LEU LEU C . n 
C 1 146 SER 146 353 353 SER SER C . n 
C 1 147 ILE 147 354 354 ILE ILE C . n 
C 1 148 LYS 148 355 355 LYS LYS C . n 
C 1 149 GLY 149 356 356 GLY GLY C . n 
C 1 150 LYS 150 357 357 LYS LYS C . n 
C 1 151 LYS 151 358 358 LYS LYS C . n 
C 1 152 ASN 152 359 359 ASN ASN C . n 
C 1 153 ILE 153 360 360 ILE ILE C . n 
C 1 154 PHE 154 361 361 PHE PHE C . n 
C 1 155 GLU 155 362 362 GLU GLU C . n 
C 1 156 SER 156 363 363 SER SER C . n 
C 1 157 PHE 157 364 364 PHE PHE C . n 
C 1 158 VAL 158 365 365 VAL VAL C . n 
C 1 159 ASP 159 366 366 ASP ASP C . n 
C 1 160 TYR 160 367 367 TYR TYR C . n 
C 1 161 VAL 161 368 368 VAL VAL C . n 
C 1 162 ALA 162 369 369 ALA ALA C . n 
C 1 163 VAL 163 370 370 VAL VAL C . n 
C 1 164 GLU 164 371 371 GLU GLU C . n 
C 1 165 GLN 165 372 372 GLN GLN C . n 
C 1 166 LEU 166 373 373 LEU LEU C . n 
C 1 167 ASP 167 374 374 ASP ASP C . n 
C 1 168 GLY 168 375 375 GLY GLY C . n 
C 1 169 ASP 169 376 376 ASP ASP C . n 
C 1 170 ASN 170 377 377 ASN ASN C . n 
C 1 171 LYS 171 378 378 LYS LYS C . n 
C 1 172 TYR 172 379 379 TYR TYR C . n 
C 1 173 ASP 173 380 380 ASP ASP C . n 
C 1 174 ALA 174 381 381 ALA ALA C . n 
C 1 175 GLY 175 382 382 GLY GLY C . n 
C 1 176 GLU 176 383 383 GLU GLU C . n 
C 1 177 HIS 177 384 384 HIS HIS C . n 
C 1 178 GLY 178 385 385 GLY GLY C . n 
C 1 179 LEU 179 386 386 LEU LEU C . n 
C 1 180 GLN 180 387 387 GLN GLN C . n 
C 1 181 GLU 181 388 388 GLU GLU C . n 
C 1 182 ALA 182 389 389 ALA ALA C . n 
C 1 183 GLU 183 390 390 GLU GLU C . n 
C 1 184 LYS 184 391 391 LYS LYS C . n 
C 1 185 GLY 185 392 392 GLY GLY C . n 
C 1 186 VAL 186 393 393 VAL VAL C . n 
C 1 187 LYS 187 394 394 LYS LYS C . n 
C 1 188 PHE 188 395 395 PHE PHE C . n 
C 1 189 LEU 189 396 396 LEU LEU C . n 
C 1 190 THR 190 397 397 THR THR C . n 
C 1 191 LEU 191 398 398 LEU LEU C . n 
C 1 192 PRO 192 399 399 PRO PRO C . n 
C 1 193 PRO 193 400 400 PRO PRO C . n 
C 1 194 VAL 194 401 401 VAL VAL C . n 
C 1 195 LEU 195 402 402 LEU LEU C . n 
C 1 196 HIS 196 403 403 HIS HIS C . n 
C 1 197 LEU 197 404 404 LEU LEU C . n 
C 1 198 GLN 198 405 405 GLN GLN C . n 
C 1 199 LEU 199 406 406 LEU LEU C . n 
C 1 200 MET 200 407 407 MET MET C . n 
C 1 201 ARG 201 408 408 ARG ARG C . n 
C 1 202 PHE 202 409 409 PHE PHE C . n 
C 1 203 MET 203 410 410 MET MET C . n 
C 1 204 TYR 204 411 411 TYR TYR C . n 
C 1 205 ASP 205 412 ?   ?   ?   C . n 
C 1 206 PRO 206 413 ?   ?   ?   C . n 
C 1 207 GLN 207 414 ?   ?   ?   C . n 
C 1 208 THR 208 415 415 THR THR C . n 
C 1 209 ASP 209 416 416 ASP ASP C . n 
C 1 210 GLN 210 417 417 GLN GLN C . n 
C 1 211 ASN 211 418 418 ASN ASN C . n 
C 1 212 ILE 212 419 419 ILE ILE C . n 
C 1 213 LYS 213 420 420 LYS LYS C . n 
C 1 214 ILE 214 421 421 ILE ILE C . n 
C 1 215 ASN 215 422 422 ASN ASN C . n 
C 1 216 ASP 216 423 423 ASP ASP C . n 
C 1 217 ARG 217 424 424 ARG ARG C . n 
C 1 218 PHE 218 425 425 PHE PHE C . n 
C 1 219 GLU 219 426 426 GLU GLU C . n 
C 1 220 PHE 220 427 427 PHE PHE C . n 
C 1 221 PRO 221 428 428 PRO PRO C . n 
C 1 222 GLU 222 429 429 GLU GLU C . n 
C 1 223 GLN 223 430 430 GLN GLN C . n 
C 1 224 LEU 224 431 431 LEU LEU C . n 
C 1 225 PRO 225 432 432 PRO PRO C . n 
C 1 226 LEU 226 433 433 LEU LEU C . n 
C 1 227 ASP 227 434 434 ASP ASP C . n 
C 1 228 GLU 228 435 435 GLU GLU C . n 
C 1 229 PHE 229 436 436 PHE PHE C . n 
C 1 230 LEU 230 437 437 LEU LEU C . n 
C 1 231 GLN 231 438 438 GLN GLN C . n 
C 1 232 LYS 232 439 439 LYS LYS C . n 
C 1 233 THR 233 440 440 THR THR C . n 
C 1 234 ASP 234 441 441 ASP ASP C . n 
C 1 235 PRO 235 442 442 PRO PRO C . n 
C 1 236 LYS 236 443 443 LYS LYS C . n 
C 1 237 ASP 237 444 444 ASP ASP C . n 
C 1 238 PRO 238 445 445 PRO PRO C . n 
C 1 239 ALA 239 446 446 ALA ALA C . n 
C 1 240 ASN 240 447 447 ASN ASN C . n 
C 1 241 TYR 241 448 448 TYR TYR C . n 
C 1 242 ILE 242 449 449 ILE ILE C . n 
C 1 243 LEU 243 450 450 LEU LEU C . n 
C 1 244 HIS 244 451 451 HIS HIS C . n 
C 1 245 ALA 245 452 452 ALA ALA C . n 
C 1 246 VAL 246 453 453 VAL VAL C . n 
C 1 247 LEU 247 454 454 LEU LEU C . n 
C 1 248 VAL 248 455 455 VAL VAL C . n 
C 1 249 HIS 249 456 456 HIS HIS C . n 
C 1 250 SER 250 457 457 SER SER C . n 
C 1 251 GLY 251 458 458 GLY GLY C . n 
C 1 252 ASP 252 459 459 ASP ASP C . n 
C 1 253 ASN 253 460 460 ASN ASN C . n 
C 1 254 HIS 254 461 461 HIS HIS C . n 
C 1 255 GLY 255 462 462 GLY GLY C . n 
C 1 256 GLY 256 463 463 GLY GLY C . n 
C 1 257 HIS 257 464 464 HIS HIS C . n 
C 1 258 TYR 258 465 465 TYR TYR C . n 
C 1 259 VAL 259 466 466 VAL VAL C . n 
C 1 260 VAL 260 467 467 VAL VAL C . n 
C 1 261 TYR 261 468 468 TYR TYR C . n 
C 1 262 LEU 262 469 469 LEU LEU C . n 
C 1 263 ASN 263 470 470 ASN ASN C . n 
C 1 264 PRO 264 471 471 PRO PRO C . n 
C 1 265 LYS 265 472 472 LYS LYS C . n 
C 1 266 GLY 266 473 473 GLY GLY C . n 
C 1 267 ASP 267 474 474 ASP ASP C . n 
C 1 268 GLY 268 475 475 GLY GLY C . n 
C 1 269 LYS 269 476 476 LYS LYS C . n 
C 1 270 TRP 270 477 477 TRP TRP C . n 
C 1 271 CYS 271 478 478 CYS CYS C . n 
C 1 272 LYS 272 479 479 LYS LYS C . n 
C 1 273 PHE 273 480 480 PHE PHE C . n 
C 1 274 ASP 274 481 481 ASP ASP C . n 
C 1 275 ASP 275 482 482 ASP ASP C . n 
C 1 276 ASP 276 483 483 ASP ASP C . n 
C 1 277 VAL 277 484 484 VAL VAL C . n 
C 1 278 VAL 278 485 485 VAL VAL C . n 
C 1 279 SER 279 486 486 SER SER C . n 
C 1 280 ARG 280 487 487 ARG ARG C . n 
C 1 281 CYS 281 488 488 CYS CYS C . n 
C 1 282 THR 282 489 489 THR THR C . n 
C 1 283 LYS 283 490 490 LYS LYS C . n 
C 1 284 GLU 284 491 491 GLU GLU C . n 
C 1 285 GLU 285 492 492 GLU GLU C . n 
C 1 286 ALA 286 493 493 ALA ALA C . n 
C 1 287 ILE 287 494 494 ILE ILE C . n 
C 1 288 GLU 288 495 495 GLU GLU C . n 
C 1 289 HIS 289 496 496 HIS HIS C . n 
C 1 290 ASN 290 497 497 ASN ASN C . n 
C 1 291 TYR 291 498 498 TYR TYR C . n 
C 1 292 GLY 292 499 499 GLY GLY C . n 
C 1 293 GLY 293 500 500 GLY GLY C . n 
C 1 294 HIS 294 501 ?   ?   ?   C . n 
C 1 295 ASP 295 502 ?   ?   ?   C . n 
C 1 296 ASP 296 503 ?   ?   ?   C . n 
C 1 297 ASP 297 504 ?   ?   ?   C . n 
C 1 298 LEU 298 505 ?   ?   ?   C . n 
C 1 299 SER 299 506 ?   ?   ?   C . n 
C 1 300 VAL 300 507 ?   ?   ?   C . n 
C 1 301 ARG 301 508 ?   ?   ?   C . n 
C 1 302 HIS 302 509 ?   ?   ?   C . n 
C 1 303 CYS 303 510 510 CYS CYS C . n 
C 1 304 THR 304 511 511 THR THR C . n 
C 1 305 ASN 305 512 512 ASN ASN C . n 
C 1 306 ALA 306 513 513 ALA ALA C . n 
C 1 307 TYR 307 514 514 TYR TYR C . n 
C 1 308 MET 308 515 515 MET MET C . n 
C 1 309 LEU 309 516 516 LEU LEU C . n 
C 1 310 VAL 310 517 517 VAL VAL C . n 
C 1 311 TYR 311 518 518 TYR TYR C . n 
C 1 312 ILE 312 519 519 ILE ILE C . n 
C 1 313 ARG 313 520 520 ARG ARG C . n 
C 1 314 GLU 314 521 521 GLU GLU C . n 
C 1 315 SER 315 522 522 SER SER C . n 
C 1 316 LYS 316 523 523 LYS LYS C . n 
C 1 317 LEU 317 524 524 LEU LEU C . n 
C 1 318 SER 318 525 525 SER SER C . n 
C 1 319 GLU 319 526 526 GLU GLU C . n 
C 1 320 VAL 320 527 527 VAL VAL C . n 
C 1 321 LEU 321 528 528 LEU LEU C . n 
C 1 322 GLN 322 529 529 GLN GLN C . n 
C 1 323 ALA 323 530 530 ALA ALA C . n 
C 1 324 VAL 324 531 531 VAL VAL C . n 
C 1 325 THR 325 532 532 THR THR C . n 
C 1 326 ASP 326 533 533 ASP ASP C . n 
C 1 327 HIS 327 534 534 HIS HIS C . n 
C 1 328 ASP 328 535 535 ASP ASP C . n 
C 1 329 ILE 329 536 536 ILE ILE C . n 
C 1 330 PRO 330 537 537 PRO PRO C . n 
C 1 331 GLN 331 538 538 GLN GLN C . n 
C 1 332 GLN 332 539 539 GLN GLN C . n 
C 1 333 LEU 333 540 540 LEU LEU C . n 
C 1 334 VAL 334 541 541 VAL VAL C . n 
C 1 335 GLU 335 542 542 GLU GLU C . n 
C 1 336 ARG 336 543 543 ARG ARG C . n 
C 1 337 LEU 337 544 544 LEU LEU C . n 
C 1 338 GLN 338 545 545 GLN GLN C . n 
C 1 339 GLU 339 546 546 GLU GLU C . n 
C 1 340 GLU 340 547 547 GLU GLU C . n 
C 1 341 LYS 341 548 548 LYS LYS C . n 
C 1 342 ARG 342 549 549 ARG ARG C . n 
C 1 343 ILE 343 550 550 ILE ILE C . n 
C 1 344 GLU 344 551 551 GLU GLU C . n 
C 1 345 ALA 345 552 552 ALA ALA C . n 
C 1 346 GLN 346 553 ?   ?   ?   C . n 
C 1 347 LYS 347 554 ?   ?   ?   C . n 
C 1 348 ARG 348 555 ?   ?   ?   C . n 
C 1 349 LYS 349 556 ?   ?   ?   C . n 
C 1 350 GLU 350 557 ?   ?   ?   C . n 
C 1 351 ARG 351 558 ?   ?   ?   C . n 
C 1 352 GLN 352 559 ?   ?   ?   C . n 
C 1 353 GLU 353 560 ?   ?   ?   C . n 
D 2 1   MET 1   1   1   MET MET D . n 
D 2 2   GLN 2   2   2   GLN GLN D . n 
D 2 3   ILE 3   3   3   ILE ILE D . n 
D 2 4   PHE 4   4   4   PHE PHE D . n 
D 2 5   VAL 5   5   5   VAL VAL D . n 
D 2 6   LYS 6   6   6   LYS LYS D . n 
D 2 7   THR 7   7   7   THR THR D . n 
D 2 8   LEU 8   8   8   LEU LEU D . n 
D 2 9   THR 9   9   9   THR THR D . n 
D 2 10  GLY 10  10  10  GLY GLY D . n 
D 2 11  LYS 11  11  11  LYS LYS D . n 
D 2 12  THR 12  12  12  THR THR D . n 
D 2 13  ILE 13  13  13  ILE ILE D . n 
D 2 14  THR 14  14  14  THR THR D . n 
D 2 15  LEU 15  15  15  LEU LEU D . n 
D 2 16  GLU 16  16  16  GLU GLU D . n 
D 2 17  VAL 17  17  17  VAL VAL D . n 
D 2 18  GLU 18  18  18  GLU GLU D . n 
D 2 19  PRO 19  19  19  PRO PRO D . n 
D 2 20  SER 20  20  20  SER SER D . n 
D 2 21  ASP 21  21  21  ASP ASP D . n 
D 2 22  THR 22  22  22  THR THR D . n 
D 2 23  ILE 23  23  23  ILE ILE D . n 
D 2 24  GLU 24  24  24  GLU GLU D . n 
D 2 25  ASN 25  25  25  ASN ASN D . n 
D 2 26  VAL 26  26  26  VAL VAL D . n 
D 2 27  LYS 27  27  27  LYS LYS D . n 
D 2 28  ALA 28  28  28  ALA ALA D . n 
D 2 29  LYS 29  29  29  LYS LYS D . n 
D 2 30  ILE 30  30  30  ILE ILE D . n 
D 2 31  GLN 31  31  31  GLN GLN D . n 
D 2 32  ASP 32  32  32  ASP ASP D . n 
D 2 33  LYS 33  33  33  LYS LYS D . n 
D 2 34  GLU 34  34  34  GLU GLU D . n 
D 2 35  GLY 35  35  35  GLY GLY D . n 
D 2 36  ILE 36  36  36  ILE ILE D . n 
D 2 37  PRO 37  37  37  PRO PRO D . n 
D 2 38  PRO 38  38  38  PRO PRO D . n 
D 2 39  ASP 39  39  39  ASP ASP D . n 
D 2 40  GLN 40  40  40  GLN GLN D . n 
D 2 41  GLN 41  41  41  GLN GLN D . n 
D 2 42  ARG 42  42  42  ARG ARG D . n 
D 2 43  LEU 43  43  43  LEU LEU D . n 
D 2 44  ILE 44  44  44  ILE ILE D . n 
D 2 45  PHE 45  45  45  PHE PHE D . n 
D 2 46  ALA 46  46  46  ALA ALA D . n 
D 2 47  GLY 47  47  47  GLY GLY D . n 
D 2 48  LYS 48  48  48  LYS LYS D . n 
D 2 49  GLN 49  49  49  GLN GLN D . n 
D 2 50  LEU 50  50  50  LEU LEU D . n 
D 2 51  GLU 51  51  51  GLU GLU D . n 
D 2 52  ASP 52  52  52  ASP ASP D . n 
D 2 53  GLY 53  53  53  GLY GLY D . n 
D 2 54  ARG 54  54  54  ARG ARG D . n 
D 2 55  THR 55  55  55  THR THR D . n 
D 2 56  LEU 56  56  56  LEU LEU D . n 
D 2 57  SER 57  57  57  SER SER D . n 
D 2 58  ASP 58  58  58  ASP ASP D . n 
D 2 59  TYR 59  59  59  TYR TYR D . n 
D 2 60  ASN 60  60  60  ASN ASN D . n 
D 2 61  ILE 61  61  61  ILE ILE D . n 
D 2 62  GLN 62  62  62  GLN GLN D . n 
D 2 63  LYS 63  63  63  LYS LYS D . n 
D 2 64  GLU 64  64  64  GLU GLU D . n 
D 2 65  SER 65  65  65  SER SER D . n 
D 2 66  THR 66  66  66  THR THR D . n 
D 2 67  LEU 67  67  67  LEU LEU D . n 
D 2 68  HIS 68  68  68  HIS HIS D . n 
D 2 69  LEU 69  69  69  LEU LEU D . n 
D 2 70  VAL 70  70  70  VAL VAL D . n 
D 2 71  LEU 71  71  71  LEU LEU D . n 
D 2 72  ARG 72  72  72  ARG ARG D . n 
D 2 73  LEU 73  73  73  LEU LEU D . n 
D 2 74  ARG 74  74  74  ARG ARG D . n 
D 2 75  GLY 75  75  75  GLY GLY D . n 
E 1 1   LYS 1   208 ?   ?   ?   E . n 
E 1 2   LYS 2   209 ?   ?   ?   E . n 
E 1 3   HIS 3   210 ?   ?   ?   E . n 
E 1 4   THR 4   211 211 THR THR E . n 
E 1 5   GLY 5   212 212 GLY GLY E . n 
E 1 6   TYR 6   213 213 TYR TYR E . n 
E 1 7   VAL 7   214 214 VAL VAL E . n 
E 1 8   GLY 8   215 215 GLY GLY E . n 
E 1 9   LEU 9   216 216 LEU LEU E . n 
E 1 10  LYS 10  217 217 LYS LYS E . n 
E 1 11  ASN 11  218 218 ASN ASN E . n 
E 1 12  GLN 12  219 219 GLN GLN E . n 
E 1 13  GLY 13  220 220 GLY GLY E . n 
E 1 14  ALA 14  221 221 ALA ALA E . n 
E 1 15  THR 15  222 222 THR THR E . n 
E 1 16  CYS 16  223 223 CYS CYS E . n 
E 1 17  TYR 17  224 224 TYR TYR E . n 
E 1 18  MET 18  225 225 MET MET E . n 
E 1 19  ASN 19  226 226 ASN ASN E . n 
E 1 20  SER 20  227 227 SER SER E . n 
E 1 21  LEU 21  228 228 LEU LEU E . n 
E 1 22  LEU 22  229 229 LEU LEU E . n 
E 1 23  GLN 23  230 230 GLN GLN E . n 
E 1 24  THR 24  231 231 THR THR E . n 
E 1 25  LEU 25  232 232 LEU LEU E . n 
E 1 26  PHE 26  233 233 PHE PHE E . n 
E 1 27  PHE 27  234 234 PHE PHE E . n 
E 1 28  THR 28  235 235 THR THR E . n 
E 1 29  ASN 29  236 236 ASN ASN E . n 
E 1 30  GLN 30  237 237 GLN GLN E . n 
E 1 31  LEU 31  238 238 LEU LEU E . n 
E 1 32  ARG 32  239 239 ARG ARG E . n 
E 1 33  LYS 33  240 240 LYS LYS E . n 
E 1 34  ALA 34  241 241 ALA ALA E . n 
E 1 35  VAL 35  242 242 VAL VAL E . n 
E 1 36  TYR 36  243 243 TYR TYR E . n 
E 1 37  MET 37  244 244 MET MET E . n 
E 1 38  MET 38  245 245 MET MET E . n 
E 1 39  PRO 39  246 246 PRO PRO E . n 
E 1 40  THR 40  247 247 THR THR E . n 
E 1 41  GLU 41  248 248 GLU GLU E . n 
E 1 42  GLY 42  249 249 GLY GLY E . n 
E 1 43  ASP 43  250 250 ASP ASP E . n 
E 1 44  ASP 44  251 ?   ?   ?   E . n 
E 1 45  SER 45  252 252 SER SER E . n 
E 1 46  SER 46  253 253 SER SER E . n 
E 1 47  LYS 47  254 254 LYS LYS E . n 
E 1 48  SER 48  255 255 SER SER E . n 
E 1 49  VAL 49  256 256 VAL VAL E . n 
E 1 50  PRO 50  257 257 PRO PRO E . n 
E 1 51  LEU 51  258 258 LEU LEU E . n 
E 1 52  ALA 52  259 259 ALA ALA E . n 
E 1 53  LEU 53  260 260 LEU LEU E . n 
E 1 54  GLN 54  261 261 GLN GLN E . n 
E 1 55  ARG 55  262 262 ARG ARG E . n 
E 1 56  VAL 56  263 263 VAL VAL E . n 
E 1 57  PHE 57  264 264 PHE PHE E . n 
E 1 58  TYR 58  265 265 TYR TYR E . n 
E 1 59  GLU 59  266 266 GLU GLU E . n 
E 1 60  LEU 60  267 267 LEU LEU E . n 
E 1 61  GLN 61  268 268 GLN GLN E . n 
E 1 62  HIS 62  269 269 HIS HIS E . n 
E 1 63  SER 63  270 270 SER SER E . n 
E 1 64  ASP 64  271 271 ASP ASP E . n 
E 1 65  LYS 65  272 272 LYS LYS E . n 
E 1 66  PRO 66  273 273 PRO PRO E . n 
E 1 67  VAL 67  274 274 VAL VAL E . n 
E 1 68  GLY 68  275 275 GLY GLY E . n 
E 1 69  THR 69  276 276 THR THR E . n 
E 1 70  LYS 70  277 277 LYS LYS E . n 
E 1 71  LYS 71  278 278 LYS LYS E . n 
E 1 72  LEU 72  279 279 LEU LEU E . n 
E 1 73  THR 73  280 280 THR THR E . n 
E 1 74  LYS 74  281 281 LYS LYS E . n 
E 1 75  SER 75  282 282 SER SER E . n 
E 1 76  PHE 76  283 283 PHE PHE E . n 
E 1 77  GLY 77  284 284 GLY GLY E . n 
E 1 78  TRP 78  285 285 TRP TRP E . n 
E 1 79  GLU 79  286 286 GLU GLU E . n 
E 1 80  THR 80  287 287 THR THR E . n 
E 1 81  LEU 81  288 288 LEU LEU E . n 
E 1 82  ASP 82  289 289 ASP ASP E . n 
E 1 83  SER 83  290 290 SER SER E . n 
E 1 84  PHE 84  291 291 PHE PHE E . n 
E 1 85  MET 85  292 292 MET MET E . n 
E 1 86  GLN 86  293 293 GLN GLN E . n 
E 1 87  HIS 87  294 294 HIS HIS E . n 
E 1 88  ASP 88  295 295 ASP ASP E . n 
E 1 89  VAL 89  296 296 VAL VAL E . n 
E 1 90  GLN 90  297 297 GLN GLN E . n 
E 1 91  GLU 91  298 298 GLU GLU E . n 
E 1 92  LEU 92  299 299 LEU LEU E . n 
E 1 93  CYS 93  300 300 CYS CYS E . n 
E 1 94  ARG 94  301 301 ARG ARG E . n 
E 1 95  VAL 95  302 302 VAL VAL E . n 
E 1 96  LEU 96  303 303 LEU LEU E . n 
E 1 97  LEU 97  304 304 LEU LEU E . n 
E 1 98  ASP 98  305 305 ASP ASP E . n 
E 1 99  ASN 99  306 306 ASN ASN E . n 
E 1 100 VAL 100 307 307 VAL VAL E . n 
E 1 101 GLU 101 308 308 GLU GLU E . n 
E 1 102 ASN 102 309 309 ASN ASN E . n 
E 1 103 LYS 103 310 310 LYS LYS E . n 
E 1 104 MET 104 311 311 MET MET E . n 
E 1 105 LYS 105 312 312 LYS LYS E . n 
E 1 106 GLY 106 313 313 GLY GLY E . n 
E 1 107 THR 107 314 314 THR THR E . n 
E 1 108 CYS 108 315 315 CYS CYS E . n 
E 1 109 VAL 109 316 316 VAL VAL E . n 
E 1 110 GLU 110 317 317 GLU GLU E . n 
E 1 111 GLY 111 318 318 GLY GLY E . n 
E 1 112 THR 112 319 319 THR THR E . n 
E 1 113 ILE 113 320 320 ILE ILE E . n 
E 1 114 PRO 114 321 321 PRO PRO E . n 
E 1 115 LYS 115 322 322 LYS LYS E . n 
E 1 116 LEU 116 323 323 LEU LEU E . n 
E 1 117 PHE 117 324 324 PHE PHE E . n 
E 1 118 ARG 118 325 325 ARG ARG E . n 
E 1 119 GLY 119 326 326 GLY GLY E . n 
E 1 120 LYS 120 327 327 LYS LYS E . n 
E 1 121 MET 121 328 328 MET MET E . n 
E 1 122 VAL 122 329 329 VAL VAL E . n 
E 1 123 SER 123 330 330 SER SER E . n 
E 1 124 TYR 124 331 331 TYR TYR E . n 
E 1 125 ILE 125 332 332 ILE ILE E . n 
E 1 126 GLN 126 333 333 GLN GLN E . n 
E 1 127 CYS 127 334 334 CYS CYS E . n 
E 1 128 LYS 128 335 335 LYS LYS E . n 
E 1 129 GLU 129 336 336 GLU GLU E . n 
E 1 130 VAL 130 337 337 VAL VAL E . n 
E 1 131 ASP 131 338 338 ASP ASP E . n 
E 1 132 TYR 132 339 339 TYR TYR E . n 
E 1 133 ARG 133 340 340 ARG ARG E . n 
E 1 134 SER 134 341 341 SER SER E . n 
E 1 135 ASP 135 342 342 ASP ASP E . n 
E 1 136 ARG 136 343 343 ARG ARG E . n 
E 1 137 ARG 137 344 344 ARG ARG E . n 
E 1 138 GLU 138 345 345 GLU GLU E . n 
E 1 139 ASP 139 346 346 ASP ASP E . n 
E 1 140 TYR 140 347 347 TYR TYR E . n 
E 1 141 TYR 141 348 348 TYR TYR E . n 
E 1 142 ASP 142 349 349 ASP ASP E . n 
E 1 143 ILE 143 350 350 ILE ILE E . n 
E 1 144 GLN 144 351 351 GLN GLN E . n 
E 1 145 LEU 145 352 352 LEU LEU E . n 
E 1 146 SER 146 353 353 SER SER E . n 
E 1 147 ILE 147 354 354 ILE ILE E . n 
E 1 148 LYS 148 355 355 LYS LYS E . n 
E 1 149 GLY 149 356 356 GLY GLY E . n 
E 1 150 LYS 150 357 357 LYS LYS E . n 
E 1 151 LYS 151 358 358 LYS LYS E . n 
E 1 152 ASN 152 359 359 ASN ASN E . n 
E 1 153 ILE 153 360 360 ILE ILE E . n 
E 1 154 PHE 154 361 361 PHE PHE E . n 
E 1 155 GLU 155 362 362 GLU GLU E . n 
E 1 156 SER 156 363 363 SER SER E . n 
E 1 157 PHE 157 364 364 PHE PHE E . n 
E 1 158 VAL 158 365 365 VAL VAL E . n 
E 1 159 ASP 159 366 366 ASP ASP E . n 
E 1 160 TYR 160 367 367 TYR TYR E . n 
E 1 161 VAL 161 368 368 VAL VAL E . n 
E 1 162 ALA 162 369 369 ALA ALA E . n 
E 1 163 VAL 163 370 370 VAL VAL E . n 
E 1 164 GLU 164 371 371 GLU GLU E . n 
E 1 165 GLN 165 372 372 GLN GLN E . n 
E 1 166 LEU 166 373 373 LEU LEU E . n 
E 1 167 ASP 167 374 374 ASP ASP E . n 
E 1 168 GLY 168 375 375 GLY GLY E . n 
E 1 169 ASP 169 376 376 ASP ASP E . n 
E 1 170 ASN 170 377 377 ASN ASN E . n 
E 1 171 LYS 171 378 378 LYS LYS E . n 
E 1 172 TYR 172 379 379 TYR TYR E . n 
E 1 173 ASP 173 380 380 ASP ASP E . n 
E 1 174 ALA 174 381 381 ALA ALA E . n 
E 1 175 GLY 175 382 382 GLY GLY E . n 
E 1 176 GLU 176 383 383 GLU GLU E . n 
E 1 177 HIS 177 384 384 HIS HIS E . n 
E 1 178 GLY 178 385 385 GLY GLY E . n 
E 1 179 LEU 179 386 386 LEU LEU E . n 
E 1 180 GLN 180 387 387 GLN GLN E . n 
E 1 181 GLU 181 388 388 GLU GLU E . n 
E 1 182 ALA 182 389 389 ALA ALA E . n 
E 1 183 GLU 183 390 390 GLU GLU E . n 
E 1 184 LYS 184 391 391 LYS LYS E . n 
E 1 185 GLY 185 392 392 GLY GLY E . n 
E 1 186 VAL 186 393 393 VAL VAL E . n 
E 1 187 LYS 187 394 394 LYS LYS E . n 
E 1 188 PHE 188 395 395 PHE PHE E . n 
E 1 189 LEU 189 396 396 LEU LEU E . n 
E 1 190 THR 190 397 397 THR THR E . n 
E 1 191 LEU 191 398 398 LEU LEU E . n 
E 1 192 PRO 192 399 399 PRO PRO E . n 
E 1 193 PRO 193 400 400 PRO PRO E . n 
E 1 194 VAL 194 401 401 VAL VAL E . n 
E 1 195 LEU 195 402 402 LEU LEU E . n 
E 1 196 HIS 196 403 403 HIS HIS E . n 
E 1 197 LEU 197 404 404 LEU LEU E . n 
E 1 198 GLN 198 405 405 GLN GLN E . n 
E 1 199 LEU 199 406 406 LEU LEU E . n 
E 1 200 MET 200 407 407 MET MET E . n 
E 1 201 ARG 201 408 408 ARG ARG E . n 
E 1 202 PHE 202 409 409 PHE PHE E . n 
E 1 203 MET 203 410 410 MET MET E . n 
E 1 204 TYR 204 411 ?   ?   ?   E . n 
E 1 205 ASP 205 412 ?   ?   ?   E . n 
E 1 206 PRO 206 413 ?   ?   ?   E . n 
E 1 207 GLN 207 414 ?   ?   ?   E . n 
E 1 208 THR 208 415 ?   ?   ?   E . n 
E 1 209 ASP 209 416 ?   ?   ?   E . n 
E 1 210 GLN 210 417 417 GLN GLN E . n 
E 1 211 ASN 211 418 418 ASN ASN E . n 
E 1 212 ILE 212 419 419 ILE ILE E . n 
E 1 213 LYS 213 420 420 LYS LYS E . n 
E 1 214 ILE 214 421 421 ILE ILE E . n 
E 1 215 ASN 215 422 422 ASN ASN E . n 
E 1 216 ASP 216 423 423 ASP ASP E . n 
E 1 217 ARG 217 424 424 ARG ARG E . n 
E 1 218 PHE 218 425 425 PHE PHE E . n 
E 1 219 GLU 219 426 426 GLU GLU E . n 
E 1 220 PHE 220 427 427 PHE PHE E . n 
E 1 221 PRO 221 428 428 PRO PRO E . n 
E 1 222 GLU 222 429 429 GLU GLU E . n 
E 1 223 GLN 223 430 430 GLN GLN E . n 
E 1 224 LEU 224 431 431 LEU LEU E . n 
E 1 225 PRO 225 432 432 PRO PRO E . n 
E 1 226 LEU 226 433 433 LEU LEU E . n 
E 1 227 ASP 227 434 434 ASP ASP E . n 
E 1 228 GLU 228 435 435 GLU GLU E . n 
E 1 229 PHE 229 436 436 PHE PHE E . n 
E 1 230 LEU 230 437 437 LEU LEU E . n 
E 1 231 GLN 231 438 438 GLN GLN E . n 
E 1 232 LYS 232 439 439 LYS LYS E . n 
E 1 233 THR 233 440 440 THR THR E . n 
E 1 234 ASP 234 441 441 ASP ASP E . n 
E 1 235 PRO 235 442 442 PRO PRO E . n 
E 1 236 LYS 236 443 443 LYS LYS E . n 
E 1 237 ASP 237 444 444 ASP ASP E . n 
E 1 238 PRO 238 445 445 PRO PRO E . n 
E 1 239 ALA 239 446 446 ALA ALA E . n 
E 1 240 ASN 240 447 447 ASN ASN E . n 
E 1 241 TYR 241 448 448 TYR TYR E . n 
E 1 242 ILE 242 449 449 ILE ILE E . n 
E 1 243 LEU 243 450 450 LEU LEU E . n 
E 1 244 HIS 244 451 451 HIS HIS E . n 
E 1 245 ALA 245 452 452 ALA ALA E . n 
E 1 246 VAL 246 453 453 VAL VAL E . n 
E 1 247 LEU 247 454 454 LEU LEU E . n 
E 1 248 VAL 248 455 455 VAL VAL E . n 
E 1 249 HIS 249 456 456 HIS HIS E . n 
E 1 250 SER 250 457 457 SER SER E . n 
E 1 251 GLY 251 458 458 GLY GLY E . n 
E 1 252 ASP 252 459 459 ASP ASP E . n 
E 1 253 ASN 253 460 460 ASN ASN E . n 
E 1 254 HIS 254 461 461 HIS HIS E . n 
E 1 255 GLY 255 462 462 GLY GLY E . n 
E 1 256 GLY 256 463 463 GLY GLY E . n 
E 1 257 HIS 257 464 464 HIS HIS E . n 
E 1 258 TYR 258 465 465 TYR TYR E . n 
E 1 259 VAL 259 466 466 VAL VAL E . n 
E 1 260 VAL 260 467 467 VAL VAL E . n 
E 1 261 TYR 261 468 468 TYR TYR E . n 
E 1 262 LEU 262 469 469 LEU LEU E . n 
E 1 263 ASN 263 470 470 ASN ASN E . n 
E 1 264 PRO 264 471 471 PRO PRO E . n 
E 1 265 LYS 265 472 472 LYS LYS E . n 
E 1 266 GLY 266 473 473 GLY GLY E . n 
E 1 267 ASP 267 474 474 ASP ASP E . n 
E 1 268 GLY 268 475 475 GLY GLY E . n 
E 1 269 LYS 269 476 476 LYS LYS E . n 
E 1 270 TRP 270 477 477 TRP TRP E . n 
E 1 271 CYS 271 478 478 CYS CYS E . n 
E 1 272 LYS 272 479 479 LYS LYS E . n 
E 1 273 PHE 273 480 480 PHE PHE E . n 
E 1 274 ASP 274 481 481 ASP ASP E . n 
E 1 275 ASP 275 482 482 ASP ASP E . n 
E 1 276 ASP 276 483 483 ASP ASP E . n 
E 1 277 VAL 277 484 484 VAL VAL E . n 
E 1 278 VAL 278 485 485 VAL VAL E . n 
E 1 279 SER 279 486 486 SER SER E . n 
E 1 280 ARG 280 487 487 ARG ARG E . n 
E 1 281 CYS 281 488 488 CYS CYS E . n 
E 1 282 THR 282 489 489 THR THR E . n 
E 1 283 LYS 283 490 490 LYS LYS E . n 
E 1 284 GLU 284 491 491 GLU GLU E . n 
E 1 285 GLU 285 492 492 GLU GLU E . n 
E 1 286 ALA 286 493 493 ALA ALA E . n 
E 1 287 ILE 287 494 494 ILE ILE E . n 
E 1 288 GLU 288 495 495 GLU GLU E . n 
E 1 289 HIS 289 496 496 HIS HIS E . n 
E 1 290 ASN 290 497 497 ASN ASN E . n 
E 1 291 TYR 291 498 498 TYR TYR E . n 
E 1 292 GLY 292 499 499 GLY GLY E . n 
E 1 293 GLY 293 500 500 GLY GLY E . n 
E 1 294 HIS 294 501 ?   ?   ?   E . n 
E 1 295 ASP 295 502 ?   ?   ?   E . n 
E 1 296 ASP 296 503 ?   ?   ?   E . n 
E 1 297 ASP 297 504 ?   ?   ?   E . n 
E 1 298 LEU 298 505 ?   ?   ?   E . n 
E 1 299 SER 299 506 ?   ?   ?   E . n 
E 1 300 VAL 300 507 ?   ?   ?   E . n 
E 1 301 ARG 301 508 508 ARG ARG E . n 
E 1 302 HIS 302 509 509 HIS HIS E . n 
E 1 303 CYS 303 510 510 CYS CYS E . n 
E 1 304 THR 304 511 511 THR THR E . n 
E 1 305 ASN 305 512 512 ASN ASN E . n 
E 1 306 ALA 306 513 513 ALA ALA E . n 
E 1 307 TYR 307 514 514 TYR TYR E . n 
E 1 308 MET 308 515 515 MET MET E . n 
E 1 309 LEU 309 516 516 LEU LEU E . n 
E 1 310 VAL 310 517 517 VAL VAL E . n 
E 1 311 TYR 311 518 518 TYR TYR E . n 
E 1 312 ILE 312 519 519 ILE ILE E . n 
E 1 313 ARG 313 520 520 ARG ARG E . n 
E 1 314 GLU 314 521 521 GLU GLU E . n 
E 1 315 SER 315 522 522 SER SER E . n 
E 1 316 LYS 316 523 523 LYS LYS E . n 
E 1 317 LEU 317 524 524 LEU LEU E . n 
E 1 318 SER 318 525 525 SER SER E . n 
E 1 319 GLU 319 526 526 GLU GLU E . n 
E 1 320 VAL 320 527 527 VAL VAL E . n 
E 1 321 LEU 321 528 528 LEU LEU E . n 
E 1 322 GLN 322 529 529 GLN GLN E . n 
E 1 323 ALA 323 530 530 ALA ALA E . n 
E 1 324 VAL 324 531 531 VAL VAL E . n 
E 1 325 THR 325 532 532 THR THR E . n 
E 1 326 ASP 326 533 533 ASP ASP E . n 
E 1 327 HIS 327 534 534 HIS HIS E . n 
E 1 328 ASP 328 535 535 ASP ASP E . n 
E 1 329 ILE 329 536 536 ILE ILE E . n 
E 1 330 PRO 330 537 537 PRO PRO E . n 
E 1 331 GLN 331 538 538 GLN GLN E . n 
E 1 332 GLN 332 539 539 GLN GLN E . n 
E 1 333 LEU 333 540 540 LEU LEU E . n 
E 1 334 VAL 334 541 541 VAL VAL E . n 
E 1 335 GLU 335 542 542 GLU GLU E . n 
E 1 336 ARG 336 543 543 ARG ARG E . n 
E 1 337 LEU 337 544 544 LEU LEU E . n 
E 1 338 GLN 338 545 545 GLN GLN E . n 
E 1 339 GLU 339 546 546 GLU GLU E . n 
E 1 340 GLU 340 547 547 GLU GLU E . n 
E 1 341 LYS 341 548 ?   ?   ?   E . n 
E 1 342 ARG 342 549 ?   ?   ?   E . n 
E 1 343 ILE 343 550 ?   ?   ?   E . n 
E 1 344 GLU 344 551 ?   ?   ?   E . n 
E 1 345 ALA 345 552 ?   ?   ?   E . n 
E 1 346 GLN 346 553 ?   ?   ?   E . n 
E 1 347 LYS 347 554 ?   ?   ?   E . n 
E 1 348 ARG 348 555 ?   ?   ?   E . n 
E 1 349 LYS 349 556 ?   ?   ?   E . n 
E 1 350 GLU 350 557 ?   ?   ?   E . n 
E 1 351 ARG 351 558 ?   ?   ?   E . n 
E 1 352 GLN 352 559 ?   ?   ?   E . n 
E 1 353 GLU 353 560 ?   ?   ?   E . n 
F 2 1   MET 1   1   1   MET MET F . n 
F 2 2   GLN 2   2   2   GLN GLN F . n 
F 2 3   ILE 3   3   3   ILE ILE F . n 
F 2 4   PHE 4   4   4   PHE PHE F . n 
F 2 5   VAL 5   5   5   VAL VAL F . n 
F 2 6   LYS 6   6   6   LYS LYS F . n 
F 2 7   THR 7   7   7   THR THR F . n 
F 2 8   LEU 8   8   8   LEU LEU F . n 
F 2 9   THR 9   9   9   THR THR F . n 
F 2 10  GLY 10  10  10  GLY GLY F . n 
F 2 11  LYS 11  11  11  LYS LYS F . n 
F 2 12  THR 12  12  12  THR THR F . n 
F 2 13  ILE 13  13  13  ILE ILE F . n 
F 2 14  THR 14  14  14  THR THR F . n 
F 2 15  LEU 15  15  15  LEU LEU F . n 
F 2 16  GLU 16  16  16  GLU GLU F . n 
F 2 17  VAL 17  17  17  VAL VAL F . n 
F 2 18  GLU 18  18  18  GLU GLU F . n 
F 2 19  PRO 19  19  19  PRO PRO F . n 
F 2 20  SER 20  20  20  SER SER F . n 
F 2 21  ASP 21  21  21  ASP ASP F . n 
F 2 22  THR 22  22  22  THR THR F . n 
F 2 23  ILE 23  23  23  ILE ILE F . n 
F 2 24  GLU 24  24  24  GLU GLU F . n 
F 2 25  ASN 25  25  25  ASN ASN F . n 
F 2 26  VAL 26  26  26  VAL VAL F . n 
F 2 27  LYS 27  27  27  LYS LYS F . n 
F 2 28  ALA 28  28  28  ALA ALA F . n 
F 2 29  LYS 29  29  29  LYS LYS F . n 
F 2 30  ILE 30  30  30  ILE ILE F . n 
F 2 31  GLN 31  31  31  GLN GLN F . n 
F 2 32  ASP 32  32  32  ASP ASP F . n 
F 2 33  LYS 33  33  33  LYS LYS F . n 
F 2 34  GLU 34  34  34  GLU GLU F . n 
F 2 35  GLY 35  35  35  GLY GLY F . n 
F 2 36  ILE 36  36  36  ILE ILE F . n 
F 2 37  PRO 37  37  37  PRO PRO F . n 
F 2 38  PRO 38  38  38  PRO PRO F . n 
F 2 39  ASP 39  39  39  ASP ASP F . n 
F 2 40  GLN 40  40  40  GLN GLN F . n 
F 2 41  GLN 41  41  41  GLN GLN F . n 
F 2 42  ARG 42  42  42  ARG ARG F . n 
F 2 43  LEU 43  43  43  LEU LEU F . n 
F 2 44  ILE 44  44  44  ILE ILE F . n 
F 2 45  PHE 45  45  45  PHE PHE F . n 
F 2 46  ALA 46  46  46  ALA ALA F . n 
F 2 47  GLY 47  47  47  GLY GLY F . n 
F 2 48  LYS 48  48  48  LYS LYS F . n 
F 2 49  GLN 49  49  49  GLN GLN F . n 
F 2 50  LEU 50  50  50  LEU LEU F . n 
F 2 51  GLU 51  51  51  GLU GLU F . n 
F 2 52  ASP 52  52  52  ASP ASP F . n 
F 2 53  GLY 53  53  53  GLY GLY F . n 
F 2 54  ARG 54  54  54  ARG ARG F . n 
F 2 55  THR 55  55  55  THR THR F . n 
F 2 56  LEU 56  56  56  LEU LEU F . n 
F 2 57  SER 57  57  57  SER SER F . n 
F 2 58  ASP 58  58  58  ASP ASP F . n 
F 2 59  TYR 59  59  59  TYR TYR F . n 
F 2 60  ASN 60  60  60  ASN ASN F . n 
F 2 61  ILE 61  61  61  ILE ILE F . n 
F 2 62  GLN 62  62  62  GLN GLN F . n 
F 2 63  LYS 63  63  63  LYS LYS F . n 
F 2 64  GLU 64  64  64  GLU GLU F . n 
F 2 65  SER 65  65  65  SER SER F . n 
F 2 66  THR 66  66  66  THR THR F . n 
F 2 67  LEU 67  67  67  LEU LEU F . n 
F 2 68  HIS 68  68  68  HIS HIS F . n 
F 2 69  LEU 69  69  69  LEU LEU F . n 
F 2 70  VAL 70  70  70  VAL VAL F . n 
F 2 71  LEU 71  71  71  LEU LEU F . n 
F 2 72  ARG 72  72  72  ARG ARG F . n 
F 2 73  LEU 73  73  73  LEU LEU F . n 
F 2 74  ARG 74  74  74  ARG ARG F . n 
F 2 75  GLY 75  75  75  GLY GLY F . n 
G 1 1   LYS 1   208 ?   ?   ?   G . n 
G 1 2   LYS 2   209 ?   ?   ?   G . n 
G 1 3   HIS 3   210 ?   ?   ?   G . n 
G 1 4   THR 4   211 ?   ?   ?   G . n 
G 1 5   GLY 5   212 ?   ?   ?   G . n 
G 1 6   TYR 6   213 ?   ?   ?   G . n 
G 1 7   VAL 7   214 214 VAL VAL G . n 
G 1 8   GLY 8   215 215 GLY GLY G . n 
G 1 9   LEU 9   216 216 LEU LEU G . n 
G 1 10  LYS 10  217 217 LYS LYS G . n 
G 1 11  ASN 11  218 218 ASN ASN G . n 
G 1 12  GLN 12  219 219 GLN GLN G . n 
G 1 13  GLY 13  220 220 GLY GLY G . n 
G 1 14  ALA 14  221 221 ALA ALA G . n 
G 1 15  THR 15  222 222 THR THR G . n 
G 1 16  CYS 16  223 223 CYS CYS G . n 
G 1 17  TYR 17  224 224 TYR TYR G . n 
G 1 18  MET 18  225 225 MET MET G . n 
G 1 19  ASN 19  226 226 ASN ASN G . n 
G 1 20  SER 20  227 227 SER SER G . n 
G 1 21  LEU 21  228 228 LEU LEU G . n 
G 1 22  LEU 22  229 229 LEU LEU G . n 
G 1 23  GLN 23  230 230 GLN GLN G . n 
G 1 24  THR 24  231 231 THR THR G . n 
G 1 25  LEU 25  232 232 LEU LEU G . n 
G 1 26  PHE 26  233 233 PHE PHE G . n 
G 1 27  PHE 27  234 234 PHE PHE G . n 
G 1 28  THR 28  235 235 THR THR G . n 
G 1 29  ASN 29  236 236 ASN ASN G . n 
G 1 30  GLN 30  237 237 GLN GLN G . n 
G 1 31  LEU 31  238 238 LEU LEU G . n 
G 1 32  ARG 32  239 239 ARG ARG G . n 
G 1 33  LYS 33  240 240 LYS LYS G . n 
G 1 34  ALA 34  241 241 ALA ALA G . n 
G 1 35  VAL 35  242 242 VAL VAL G . n 
G 1 36  TYR 36  243 243 TYR TYR G . n 
G 1 37  MET 37  244 244 MET MET G . n 
G 1 38  MET 38  245 245 MET MET G . n 
G 1 39  PRO 39  246 246 PRO PRO G . n 
G 1 40  THR 40  247 247 THR THR G . n 
G 1 41  GLU 41  248 248 GLU GLU G . n 
G 1 42  GLY 42  249 ?   ?   ?   G . n 
G 1 43  ASP 43  250 ?   ?   ?   G . n 
G 1 44  ASP 44  251 ?   ?   ?   G . n 
G 1 45  SER 45  252 ?   ?   ?   G . n 
G 1 46  SER 46  253 253 SER SER G . n 
G 1 47  LYS 47  254 254 LYS LYS G . n 
G 1 48  SER 48  255 255 SER SER G . n 
G 1 49  VAL 49  256 256 VAL VAL G . n 
G 1 50  PRO 50  257 257 PRO PRO G . n 
G 1 51  LEU 51  258 258 LEU LEU G . n 
G 1 52  ALA 52  259 259 ALA ALA G . n 
G 1 53  LEU 53  260 260 LEU LEU G . n 
G 1 54  GLN 54  261 261 GLN GLN G . n 
G 1 55  ARG 55  262 262 ARG ARG G . n 
G 1 56  VAL 56  263 263 VAL VAL G . n 
G 1 57  PHE 57  264 264 PHE PHE G . n 
G 1 58  TYR 58  265 265 TYR TYR G . n 
G 1 59  GLU 59  266 266 GLU GLU G . n 
G 1 60  LEU 60  267 267 LEU LEU G . n 
G 1 61  GLN 61  268 268 GLN GLN G . n 
G 1 62  HIS 62  269 ?   ?   ?   G . n 
G 1 63  SER 63  270 ?   ?   ?   G . n 
G 1 64  ASP 64  271 271 ASP ASP G . n 
G 1 65  LYS 65  272 272 LYS LYS G . n 
G 1 66  PRO 66  273 273 PRO PRO G . n 
G 1 67  VAL 67  274 274 VAL VAL G . n 
G 1 68  GLY 68  275 275 GLY GLY G . n 
G 1 69  THR 69  276 276 THR THR G . n 
G 1 70  LYS 70  277 277 LYS LYS G . n 
G 1 71  LYS 71  278 278 LYS LYS G . n 
G 1 72  LEU 72  279 279 LEU LEU G . n 
G 1 73  THR 73  280 280 THR THR G . n 
G 1 74  LYS 74  281 281 LYS LYS G . n 
G 1 75  SER 75  282 282 SER SER G . n 
G 1 76  PHE 76  283 283 PHE PHE G . n 
G 1 77  GLY 77  284 284 GLY GLY G . n 
G 1 78  TRP 78  285 285 TRP TRP G . n 
G 1 79  GLU 79  286 286 GLU GLU G . n 
G 1 80  THR 80  287 287 THR THR G . n 
G 1 81  LEU 81  288 288 LEU LEU G . n 
G 1 82  ASP 82  289 289 ASP ASP G . n 
G 1 83  SER 83  290 290 SER SER G . n 
G 1 84  PHE 84  291 291 PHE PHE G . n 
G 1 85  MET 85  292 292 MET MET G . n 
G 1 86  GLN 86  293 293 GLN GLN G . n 
G 1 87  HIS 87  294 294 HIS HIS G . n 
G 1 88  ASP 88  295 295 ASP ASP G . n 
G 1 89  VAL 89  296 296 VAL VAL G . n 
G 1 90  GLN 90  297 297 GLN GLN G . n 
G 1 91  GLU 91  298 298 GLU GLU G . n 
G 1 92  LEU 92  299 299 LEU LEU G . n 
G 1 93  CYS 93  300 300 CYS CYS G . n 
G 1 94  ARG 94  301 301 ARG ARG G . n 
G 1 95  VAL 95  302 302 VAL VAL G . n 
G 1 96  LEU 96  303 303 LEU LEU G . n 
G 1 97  LEU 97  304 304 LEU LEU G . n 
G 1 98  ASP 98  305 305 ASP ASP G . n 
G 1 99  ASN 99  306 306 ASN ASN G . n 
G 1 100 VAL 100 307 307 VAL VAL G . n 
G 1 101 GLU 101 308 308 GLU GLU G . n 
G 1 102 ASN 102 309 309 ASN ASN G . n 
G 1 103 LYS 103 310 310 LYS LYS G . n 
G 1 104 MET 104 311 311 MET MET G . n 
G 1 105 LYS 105 312 312 LYS LYS G . n 
G 1 106 GLY 106 313 313 GLY GLY G . n 
G 1 107 THR 107 314 314 THR THR G . n 
G 1 108 CYS 108 315 315 CYS CYS G . n 
G 1 109 VAL 109 316 316 VAL VAL G . n 
G 1 110 GLU 110 317 317 GLU GLU G . n 
G 1 111 GLY 111 318 318 GLY GLY G . n 
G 1 112 THR 112 319 319 THR THR G . n 
G 1 113 ILE 113 320 320 ILE ILE G . n 
G 1 114 PRO 114 321 321 PRO PRO G . n 
G 1 115 LYS 115 322 322 LYS LYS G . n 
G 1 116 LEU 116 323 323 LEU LEU G . n 
G 1 117 PHE 117 324 324 PHE PHE G . n 
G 1 118 ARG 118 325 325 ARG ARG G . n 
G 1 119 GLY 119 326 326 GLY GLY G . n 
G 1 120 LYS 120 327 327 LYS LYS G . n 
G 1 121 MET 121 328 328 MET MET G . n 
G 1 122 VAL 122 329 329 VAL VAL G . n 
G 1 123 SER 123 330 330 SER SER G . n 
G 1 124 TYR 124 331 331 TYR TYR G . n 
G 1 125 ILE 125 332 332 ILE ILE G . n 
G 1 126 GLN 126 333 333 GLN GLN G . n 
G 1 127 CYS 127 334 334 CYS CYS G . n 
G 1 128 LYS 128 335 335 LYS LYS G . n 
G 1 129 GLU 129 336 336 GLU GLU G . n 
G 1 130 VAL 130 337 337 VAL VAL G . n 
G 1 131 ASP 131 338 338 ASP ASP G . n 
G 1 132 TYR 132 339 339 TYR TYR G . n 
G 1 133 ARG 133 340 340 ARG ARG G . n 
G 1 134 SER 134 341 341 SER SER G . n 
G 1 135 ASP 135 342 342 ASP ASP G . n 
G 1 136 ARG 136 343 343 ARG ARG G . n 
G 1 137 ARG 137 344 344 ARG ARG G . n 
G 1 138 GLU 138 345 345 GLU GLU G . n 
G 1 139 ASP 139 346 346 ASP ASP G . n 
G 1 140 TYR 140 347 347 TYR TYR G . n 
G 1 141 TYR 141 348 348 TYR TYR G . n 
G 1 142 ASP 142 349 349 ASP ASP G . n 
G 1 143 ILE 143 350 350 ILE ILE G . n 
G 1 144 GLN 144 351 351 GLN GLN G . n 
G 1 145 LEU 145 352 352 LEU LEU G . n 
G 1 146 SER 146 353 353 SER SER G . n 
G 1 147 ILE 147 354 354 ILE ILE G . n 
G 1 148 LYS 148 355 355 LYS LYS G . n 
G 1 149 GLY 149 356 356 GLY GLY G . n 
G 1 150 LYS 150 357 357 LYS LYS G . n 
G 1 151 LYS 151 358 358 LYS LYS G . n 
G 1 152 ASN 152 359 359 ASN ASN G . n 
G 1 153 ILE 153 360 360 ILE ILE G . n 
G 1 154 PHE 154 361 361 PHE PHE G . n 
G 1 155 GLU 155 362 362 GLU GLU G . n 
G 1 156 SER 156 363 363 SER SER G . n 
G 1 157 PHE 157 364 364 PHE PHE G . n 
G 1 158 VAL 158 365 365 VAL VAL G . n 
G 1 159 ASP 159 366 366 ASP ASP G . n 
G 1 160 TYR 160 367 367 TYR TYR G . n 
G 1 161 VAL 161 368 368 VAL VAL G . n 
G 1 162 ALA 162 369 369 ALA ALA G . n 
G 1 163 VAL 163 370 370 VAL VAL G . n 
G 1 164 GLU 164 371 371 GLU GLU G . n 
G 1 165 GLN 165 372 372 GLN GLN G . n 
G 1 166 LEU 166 373 373 LEU LEU G . n 
G 1 167 ASP 167 374 374 ASP ASP G . n 
G 1 168 GLY 168 375 375 GLY GLY G . n 
G 1 169 ASP 169 376 376 ASP ASP G . n 
G 1 170 ASN 170 377 377 ASN ASN G . n 
G 1 171 LYS 171 378 378 LYS LYS G . n 
G 1 172 TYR 172 379 379 TYR TYR G . n 
G 1 173 ASP 173 380 380 ASP ASP G . n 
G 1 174 ALA 174 381 381 ALA ALA G . n 
G 1 175 GLY 175 382 382 GLY GLY G . n 
G 1 176 GLU 176 383 383 GLU GLU G . n 
G 1 177 HIS 177 384 384 HIS HIS G . n 
G 1 178 GLY 178 385 385 GLY GLY G . n 
G 1 179 LEU 179 386 386 LEU LEU G . n 
G 1 180 GLN 180 387 387 GLN GLN G . n 
G 1 181 GLU 181 388 388 GLU GLU G . n 
G 1 182 ALA 182 389 389 ALA ALA G . n 
G 1 183 GLU 183 390 390 GLU GLU G . n 
G 1 184 LYS 184 391 391 LYS LYS G . n 
G 1 185 GLY 185 392 392 GLY GLY G . n 
G 1 186 VAL 186 393 393 VAL VAL G . n 
G 1 187 LYS 187 394 394 LYS LYS G . n 
G 1 188 PHE 188 395 395 PHE PHE G . n 
G 1 189 LEU 189 396 396 LEU LEU G . n 
G 1 190 THR 190 397 397 THR THR G . n 
G 1 191 LEU 191 398 398 LEU LEU G . n 
G 1 192 PRO 192 399 399 PRO PRO G . n 
G 1 193 PRO 193 400 400 PRO PRO G . n 
G 1 194 VAL 194 401 401 VAL VAL G . n 
G 1 195 LEU 195 402 402 LEU LEU G . n 
G 1 196 HIS 196 403 403 HIS HIS G . n 
G 1 197 LEU 197 404 404 LEU LEU G . n 
G 1 198 GLN 198 405 405 GLN GLN G . n 
G 1 199 LEU 199 406 406 LEU LEU G . n 
G 1 200 MET 200 407 407 MET MET G . n 
G 1 201 ARG 201 408 408 ARG ARG G . n 
G 1 202 PHE 202 409 409 PHE PHE G . n 
G 1 203 MET 203 410 410 MET MET G . n 
G 1 204 TYR 204 411 411 TYR TYR G . n 
G 1 205 ASP 205 412 412 ASP ASP G . n 
G 1 206 PRO 206 413 413 PRO PRO G . n 
G 1 207 GLN 207 414 ?   ?   ?   G . n 
G 1 208 THR 208 415 ?   ?   ?   G . n 
G 1 209 ASP 209 416 ?   ?   ?   G . n 
G 1 210 GLN 210 417 ?   ?   ?   G . n 
G 1 211 ASN 211 418 418 ASN ASN G . n 
G 1 212 ILE 212 419 419 ILE ILE G . n 
G 1 213 LYS 213 420 420 LYS LYS G . n 
G 1 214 ILE 214 421 421 ILE ILE G . n 
G 1 215 ASN 215 422 422 ASN ASN G . n 
G 1 216 ASP 216 423 423 ASP ASP G . n 
G 1 217 ARG 217 424 424 ARG ARG G . n 
G 1 218 PHE 218 425 425 PHE PHE G . n 
G 1 219 GLU 219 426 426 GLU GLU G . n 
G 1 220 PHE 220 427 427 PHE PHE G . n 
G 1 221 PRO 221 428 428 PRO PRO G . n 
G 1 222 GLU 222 429 429 GLU GLU G . n 
G 1 223 GLN 223 430 430 GLN GLN G . n 
G 1 224 LEU 224 431 431 LEU LEU G . n 
G 1 225 PRO 225 432 432 PRO PRO G . n 
G 1 226 LEU 226 433 433 LEU LEU G . n 
G 1 227 ASP 227 434 434 ASP ASP G . n 
G 1 228 GLU 228 435 435 GLU GLU G . n 
G 1 229 PHE 229 436 436 PHE PHE G . n 
G 1 230 LEU 230 437 437 LEU LEU G . n 
G 1 231 GLN 231 438 438 GLN GLN G . n 
G 1 232 LYS 232 439 439 LYS LYS G . n 
G 1 233 THR 233 440 440 THR THR G . n 
G 1 234 ASP 234 441 441 ASP ASP G . n 
G 1 235 PRO 235 442 442 PRO PRO G . n 
G 1 236 LYS 236 443 443 LYS LYS G . n 
G 1 237 ASP 237 444 444 ASP ASP G . n 
G 1 238 PRO 238 445 445 PRO PRO G . n 
G 1 239 ALA 239 446 446 ALA ALA G . n 
G 1 240 ASN 240 447 447 ASN ASN G . n 
G 1 241 TYR 241 448 448 TYR TYR G . n 
G 1 242 ILE 242 449 449 ILE ILE G . n 
G 1 243 LEU 243 450 450 LEU LEU G . n 
G 1 244 HIS 244 451 451 HIS HIS G . n 
G 1 245 ALA 245 452 452 ALA ALA G . n 
G 1 246 VAL 246 453 453 VAL VAL G . n 
G 1 247 LEU 247 454 454 LEU LEU G . n 
G 1 248 VAL 248 455 455 VAL VAL G . n 
G 1 249 HIS 249 456 456 HIS HIS G . n 
G 1 250 SER 250 457 457 SER SER G . n 
G 1 251 GLY 251 458 458 GLY GLY G . n 
G 1 252 ASP 252 459 459 ASP ASP G . n 
G 1 253 ASN 253 460 460 ASN ASN G . n 
G 1 254 HIS 254 461 461 HIS HIS G . n 
G 1 255 GLY 255 462 462 GLY GLY G . n 
G 1 256 GLY 256 463 463 GLY GLY G . n 
G 1 257 HIS 257 464 464 HIS HIS G . n 
G 1 258 TYR 258 465 465 TYR TYR G . n 
G 1 259 VAL 259 466 466 VAL VAL G . n 
G 1 260 VAL 260 467 467 VAL VAL G . n 
G 1 261 TYR 261 468 468 TYR TYR G . n 
G 1 262 LEU 262 469 469 LEU LEU G . n 
G 1 263 ASN 263 470 470 ASN ASN G . n 
G 1 264 PRO 264 471 471 PRO PRO G . n 
G 1 265 LYS 265 472 472 LYS LYS G . n 
G 1 266 GLY 266 473 473 GLY GLY G . n 
G 1 267 ASP 267 474 474 ASP ASP G . n 
G 1 268 GLY 268 475 475 GLY GLY G . n 
G 1 269 LYS 269 476 476 LYS LYS G . n 
G 1 270 TRP 270 477 477 TRP TRP G . n 
G 1 271 CYS 271 478 478 CYS CYS G . n 
G 1 272 LYS 272 479 479 LYS LYS G . n 
G 1 273 PHE 273 480 480 PHE PHE G . n 
G 1 274 ASP 274 481 481 ASP ASP G . n 
G 1 275 ASP 275 482 482 ASP ASP G . n 
G 1 276 ASP 276 483 483 ASP ASP G . n 
G 1 277 VAL 277 484 484 VAL VAL G . n 
G 1 278 VAL 278 485 485 VAL VAL G . n 
G 1 279 SER 279 486 486 SER SER G . n 
G 1 280 ARG 280 487 487 ARG ARG G . n 
G 1 281 CYS 281 488 488 CYS CYS G . n 
G 1 282 THR 282 489 489 THR THR G . n 
G 1 283 LYS 283 490 490 LYS LYS G . n 
G 1 284 GLU 284 491 491 GLU GLU G . n 
G 1 285 GLU 285 492 492 GLU GLU G . n 
G 1 286 ALA 286 493 493 ALA ALA G . n 
G 1 287 ILE 287 494 494 ILE ILE G . n 
G 1 288 GLU 288 495 495 GLU GLU G . n 
G 1 289 HIS 289 496 496 HIS HIS G . n 
G 1 290 ASN 290 497 497 ASN ASN G . n 
G 1 291 TYR 291 498 498 TYR TYR G . n 
G 1 292 GLY 292 499 ?   ?   ?   G . n 
G 1 293 GLY 293 500 ?   ?   ?   G . n 
G 1 294 HIS 294 501 ?   ?   ?   G . n 
G 1 295 ASP 295 502 ?   ?   ?   G . n 
G 1 296 ASP 296 503 ?   ?   ?   G . n 
G 1 297 ASP 297 504 ?   ?   ?   G . n 
G 1 298 LEU 298 505 ?   ?   ?   G . n 
G 1 299 SER 299 506 ?   ?   ?   G . n 
G 1 300 VAL 300 507 ?   ?   ?   G . n 
G 1 301 ARG 301 508 508 ARG ARG G . n 
G 1 302 HIS 302 509 509 HIS HIS G . n 
G 1 303 CYS 303 510 510 CYS CYS G . n 
G 1 304 THR 304 511 511 THR THR G . n 
G 1 305 ASN 305 512 512 ASN ASN G . n 
G 1 306 ALA 306 513 513 ALA ALA G . n 
G 1 307 TYR 307 514 514 TYR TYR G . n 
G 1 308 MET 308 515 515 MET MET G . n 
G 1 309 LEU 309 516 516 LEU LEU G . n 
G 1 310 VAL 310 517 517 VAL VAL G . n 
G 1 311 TYR 311 518 518 TYR TYR G . n 
G 1 312 ILE 312 519 519 ILE ILE G . n 
G 1 313 ARG 313 520 520 ARG ARG G . n 
G 1 314 GLU 314 521 521 GLU GLU G . n 
G 1 315 SER 315 522 522 SER SER G . n 
G 1 316 LYS 316 523 523 LYS LYS G . n 
G 1 317 LEU 317 524 524 LEU LEU G . n 
G 1 318 SER 318 525 525 SER SER G . n 
G 1 319 GLU 319 526 526 GLU GLU G . n 
G 1 320 VAL 320 527 527 VAL VAL G . n 
G 1 321 LEU 321 528 528 LEU LEU G . n 
G 1 322 GLN 322 529 529 GLN GLN G . n 
G 1 323 ALA 323 530 530 ALA ALA G . n 
G 1 324 VAL 324 531 ?   ?   ?   G . n 
G 1 325 THR 325 532 ?   ?   ?   G . n 
G 1 326 ASP 326 533 ?   ?   ?   G . n 
G 1 327 HIS 327 534 ?   ?   ?   G . n 
G 1 328 ASP 328 535 ?   ?   ?   G . n 
G 1 329 ILE 329 536 ?   ?   ?   G . n 
G 1 330 PRO 330 537 ?   ?   ?   G . n 
G 1 331 GLN 331 538 ?   ?   ?   G . n 
G 1 332 GLN 332 539 ?   ?   ?   G . n 
G 1 333 LEU 333 540 ?   ?   ?   G . n 
G 1 334 VAL 334 541 ?   ?   ?   G . n 
G 1 335 GLU 335 542 ?   ?   ?   G . n 
G 1 336 ARG 336 543 ?   ?   ?   G . n 
G 1 337 LEU 337 544 ?   ?   ?   G . n 
G 1 338 GLN 338 545 ?   ?   ?   G . n 
G 1 339 GLU 339 546 ?   ?   ?   G . n 
G 1 340 GLU 340 547 ?   ?   ?   G . n 
G 1 341 LYS 341 548 ?   ?   ?   G . n 
G 1 342 ARG 342 549 ?   ?   ?   G . n 
G 1 343 ILE 343 550 ?   ?   ?   G . n 
G 1 344 GLU 344 551 ?   ?   ?   G . n 
G 1 345 ALA 345 552 ?   ?   ?   G . n 
G 1 346 GLN 346 553 ?   ?   ?   G . n 
G 1 347 LYS 347 554 ?   ?   ?   G . n 
G 1 348 ARG 348 555 ?   ?   ?   G . n 
G 1 349 LYS 349 556 ?   ?   ?   G . n 
G 1 350 GLU 350 557 ?   ?   ?   G . n 
G 1 351 ARG 351 558 ?   ?   ?   G . n 
G 1 352 GLN 352 559 ?   ?   ?   G . n 
G 1 353 GLU 353 560 ?   ?   ?   G . n 
H 2 1   MET 1   1   1   MET MET H . n 
H 2 2   GLN 2   2   2   GLN GLN H . n 
H 2 3   ILE 3   3   3   ILE ILE H . n 
H 2 4   PHE 4   4   4   PHE PHE H . n 
H 2 5   VAL 5   5   5   VAL VAL H . n 
H 2 6   LYS 6   6   6   LYS LYS H . n 
H 2 7   THR 7   7   7   THR THR H . n 
H 2 8   LEU 8   8   8   LEU LEU H . n 
H 2 9   THR 9   9   9   THR THR H . n 
H 2 10  GLY 10  10  10  GLY GLY H . n 
H 2 11  LYS 11  11  11  LYS LYS H . n 
H 2 12  THR 12  12  12  THR THR H . n 
H 2 13  ILE 13  13  13  ILE ILE H . n 
H 2 14  THR 14  14  14  THR THR H . n 
H 2 15  LEU 15  15  15  LEU LEU H . n 
H 2 16  GLU 16  16  16  GLU GLU H . n 
H 2 17  VAL 17  17  17  VAL VAL H . n 
H 2 18  GLU 18  18  18  GLU GLU H . n 
H 2 19  PRO 19  19  19  PRO PRO H . n 
H 2 20  SER 20  20  20  SER SER H . n 
H 2 21  ASP 21  21  21  ASP ASP H . n 
H 2 22  THR 22  22  22  THR THR H . n 
H 2 23  ILE 23  23  23  ILE ILE H . n 
H 2 24  GLU 24  24  24  GLU GLU H . n 
H 2 25  ASN 25  25  25  ASN ASN H . n 
H 2 26  VAL 26  26  26  VAL VAL H . n 
H 2 27  LYS 27  27  27  LYS LYS H . n 
H 2 28  ALA 28  28  28  ALA ALA H . n 
H 2 29  LYS 29  29  29  LYS LYS H . n 
H 2 30  ILE 30  30  30  ILE ILE H . n 
H 2 31  GLN 31  31  31  GLN GLN H . n 
H 2 32  ASP 32  32  32  ASP ASP H . n 
H 2 33  LYS 33  33  33  LYS LYS H . n 
H 2 34  GLU 34  34  34  GLU GLU H . n 
H 2 35  GLY 35  35  35  GLY GLY H . n 
H 2 36  ILE 36  36  36  ILE ILE H . n 
H 2 37  PRO 37  37  37  PRO PRO H . n 
H 2 38  PRO 38  38  38  PRO PRO H . n 
H 2 39  ASP 39  39  39  ASP ASP H . n 
H 2 40  GLN 40  40  40  GLN GLN H . n 
H 2 41  GLN 41  41  41  GLN GLN H . n 
H 2 42  ARG 42  42  42  ARG ARG H . n 
H 2 43  LEU 43  43  43  LEU LEU H . n 
H 2 44  ILE 44  44  44  ILE ILE H . n 
H 2 45  PHE 45  45  45  PHE PHE H . n 
H 2 46  ALA 46  46  46  ALA ALA H . n 
H 2 47  GLY 47  47  47  GLY GLY H . n 
H 2 48  LYS 48  48  48  LYS LYS H . n 
H 2 49  GLN 49  49  49  GLN GLN H . n 
H 2 50  LEU 50  50  50  LEU LEU H . n 
H 2 51  GLU 51  51  51  GLU GLU H . n 
H 2 52  ASP 52  52  52  ASP ASP H . n 
H 2 53  GLY 53  53  53  GLY GLY H . n 
H 2 54  ARG 54  54  54  ARG ARG H . n 
H 2 55  THR 55  55  55  THR THR H . n 
H 2 56  LEU 56  56  56  LEU LEU H . n 
H 2 57  SER 57  57  57  SER SER H . n 
H 2 58  ASP 58  58  58  ASP ASP H . n 
H 2 59  TYR 59  59  59  TYR TYR H . n 
H 2 60  ASN 60  60  60  ASN ASN H . n 
H 2 61  ILE 61  61  61  ILE ILE H . n 
H 2 62  GLN 62  62  62  GLN GLN H . n 
H 2 63  LYS 63  63  63  LYS LYS H . n 
H 2 64  GLU 64  64  64  GLU GLU H . n 
H 2 65  SER 65  65  65  SER SER H . n 
H 2 66  THR 66  66  66  THR THR H . n 
H 2 67  LEU 67  67  67  LEU LEU H . n 
H 2 68  HIS 68  68  68  HIS HIS H . n 
H 2 69  LEU 69  69  69  LEU LEU H . n 
H 2 70  VAL 70  70  70  VAL VAL H . n 
H 2 71  LEU 71  71  71  LEU LEU H . n 
H 2 72  ARG 72  72  72  ARG ARG H . n 
H 2 73  LEU 73  73  73  LEU LEU H . n 
H 2 74  ARG 74  74  74  ARG ARG H . n 
H 2 75  GLY 75  75  75  GLY GLY H . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        SRE 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   SRE 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
I 3 SRE 1  601 601 SRE LIG C . 
J 3 SRE 1  601 601 SRE LIG G . 
K 4 HOH 1  601 83  HOH HOH A . 
K 4 HOH 2  602 49  HOH HOH A . 
K 4 HOH 3  603 74  HOH HOH A . 
K 4 HOH 4  604 1   HOH HOH A . 
K 4 HOH 5  605 87  HOH HOH A . 
K 4 HOH 6  606 6   HOH HOH A . 
K 4 HOH 7  607 2   HOH HOH A . 
K 4 HOH 8  608 12  HOH HOH A . 
K 4 HOH 9  609 33  HOH HOH A . 
K 4 HOH 10 610 5   HOH HOH A . 
K 4 HOH 11 611 16  HOH HOH A . 
K 4 HOH 12 612 13  HOH HOH A . 
L 4 HOH 1  101 102 HOH HOH B . 
L 4 HOH 2  102 31  HOH HOH B . 
L 4 HOH 3  103 29  HOH HOH B . 
L 4 HOH 4  104 10  HOH HOH B . 
L 4 HOH 5  105 18  HOH HOH B . 
L 4 HOH 6  106 21  HOH HOH B . 
L 4 HOH 7  107 76  HOH HOH B . 
L 4 HOH 8  108 46  HOH HOH B . 
L 4 HOH 9  109 34  HOH HOH B . 
M 4 HOH 1  701 97  HOH HOH C . 
M 4 HOH 2  702 48  HOH HOH C . 
M 4 HOH 3  703 24  HOH HOH C . 
M 4 HOH 4  704 22  HOH HOH C . 
M 4 HOH 5  705 30  HOH HOH C . 
M 4 HOH 6  706 70  HOH HOH C . 
M 4 HOH 7  707 89  HOH HOH C . 
M 4 HOH 8  708 79  HOH HOH C . 
M 4 HOH 9  709 28  HOH HOH C . 
M 4 HOH 10 710 104 HOH HOH C . 
M 4 HOH 11 711 77  HOH HOH C . 
M 4 HOH 12 712 81  HOH HOH C . 
N 4 HOH 1  101 19  HOH HOH D . 
N 4 HOH 2  102 52  HOH HOH D . 
O 4 HOH 1  601 78  HOH HOH E . 
O 4 HOH 2  602 45  HOH HOH E . 
O 4 HOH 3  603 7   HOH HOH E . 
O 4 HOH 4  604 59  HOH HOH E . 
O 4 HOH 5  605 61  HOH HOH E . 
O 4 HOH 6  606 72  HOH HOH E . 
O 4 HOH 7  607 8   HOH HOH E . 
O 4 HOH 8  608 94  HOH HOH E . 
O 4 HOH 9  609 11  HOH HOH E . 
O 4 HOH 10 610 73  HOH HOH E . 
P 4 HOH 1  101 38  HOH HOH F . 
P 4 HOH 2  102 3   HOH HOH F . 
P 4 HOH 3  103 84  HOH HOH F . 
P 4 HOH 4  104 17  HOH HOH F . 
P 4 HOH 5  105 57  HOH HOH F . 
Q 4 HOH 1  701 43  HOH HOH G . 
Q 4 HOH 2  702 51  HOH HOH G . 
Q 4 HOH 3  703 68  HOH HOH G . 
Q 4 HOH 4  704 69  HOH HOH G . 
Q 4 HOH 5  705 71  HOH HOH G . 
Q 4 HOH 6  706 27  HOH HOH G . 
Q 4 HOH 7  707 36  HOH HOH G . 
Q 4 HOH 8  708 50  HOH HOH G . 
R 4 HOH 1  101 60  HOH HOH H . 
R 4 HOH 2  102 9   HOH HOH H . 
R 4 HOH 3  103 15  HOH HOH H . 
R 4 HOH 4  104 20  HOH HOH H . 
R 4 HOH 5  105 4   HOH HOH H . 
R 4 HOH 6  106 82  HOH HOH H . 
R 4 HOH 7  107 55  HOH HOH H . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A LYS 240 ? CE  ? A LYS 33  CE  
2   1 Y 1 A LYS 240 ? NZ  ? A LYS 33  NZ  
3   1 Y 1 A GLU 248 ? CG  ? A GLU 41  CG  
4   1 Y 1 A GLU 248 ? CD  ? A GLU 41  CD  
5   1 Y 1 A GLU 248 ? OE1 ? A GLU 41  OE1 
6   1 Y 1 A GLU 248 ? OE2 ? A GLU 41  OE2 
7   1 Y 1 A ASP 251 ? CB  ? A ASP 44  CB  
8   1 Y 1 A ASP 251 ? CG  ? A ASP 44  CG  
9   1 Y 1 A ASP 251 ? OD1 ? A ASP 44  OD1 
10  1 Y 1 A ASP 251 ? OD2 ? A ASP 44  OD2 
11  1 Y 1 A SER 252 ? CB  ? A SER 45  CB  
12  1 Y 1 A SER 252 ? OG  ? A SER 45  OG  
13  1 Y 1 A LYS 254 ? CG  ? A LYS 47  CG  
14  1 Y 1 A LYS 254 ? CD  ? A LYS 47  CD  
15  1 Y 1 A LYS 254 ? CE  ? A LYS 47  CE  
16  1 Y 1 A LYS 254 ? NZ  ? A LYS 47  NZ  
17  1 Y 1 A LEU 258 ? CG  ? A LEU 51  CG  
18  1 Y 1 A LEU 258 ? CD1 ? A LEU 51  CD1 
19  1 Y 1 A LEU 258 ? CD2 ? A LEU 51  CD2 
20  1 Y 1 A ARG 262 ? CD  ? A ARG 55  CD  
21  1 Y 1 A ARG 262 ? NE  ? A ARG 55  NE  
22  1 Y 1 A ARG 262 ? CZ  ? A ARG 55  CZ  
23  1 Y 1 A ARG 262 ? NH1 ? A ARG 55  NH1 
24  1 Y 1 A ARG 262 ? NH2 ? A ARG 55  NH2 
25  1 Y 1 A ASP 271 ? CG  ? A ASP 64  CG  
26  1 Y 1 A ASP 271 ? OD1 ? A ASP 64  OD1 
27  1 Y 1 A ASP 271 ? OD2 ? A ASP 64  OD2 
28  1 Y 1 A LYS 272 ? CG  ? A LYS 65  CG  
29  1 Y 1 A LYS 272 ? CD  ? A LYS 65  CD  
30  1 Y 1 A LYS 272 ? CE  ? A LYS 65  CE  
31  1 Y 1 A LYS 272 ? NZ  ? A LYS 65  NZ  
32  1 Y 1 A LYS 278 ? CG  ? A LYS 71  CG  
33  1 Y 1 A LYS 278 ? CD  ? A LYS 71  CD  
34  1 Y 1 A LYS 278 ? CE  ? A LYS 71  CE  
35  1 Y 1 A LYS 278 ? NZ  ? A LYS 71  NZ  
36  1 Y 1 A LYS 281 ? CG  ? A LYS 74  CG  
37  1 Y 1 A LYS 281 ? CD  ? A LYS 74  CD  
38  1 Y 1 A LYS 281 ? CE  ? A LYS 74  CE  
39  1 Y 1 A LYS 281 ? NZ  ? A LYS 74  NZ  
40  1 Y 1 A GLU 286 ? CG  ? A GLU 79  CG  
41  1 Y 1 A GLU 286 ? CD  ? A GLU 79  CD  
42  1 Y 1 A GLU 286 ? OE1 ? A GLU 79  OE1 
43  1 Y 1 A GLU 286 ? OE2 ? A GLU 79  OE2 
44  1 Y 1 A LEU 288 ? CB  ? A LEU 81  CB  
45  1 Y 1 A LEU 288 ? CG  ? A LEU 81  CG  
46  1 Y 1 A LEU 288 ? CD1 ? A LEU 81  CD1 
47  1 Y 1 A LEU 288 ? CD2 ? A LEU 81  CD2 
48  1 Y 1 A LYS 310 ? CD  ? A LYS 103 CD  
49  1 Y 1 A LYS 310 ? CE  ? A LYS 103 CE  
50  1 Y 1 A LYS 310 ? NZ  ? A LYS 103 NZ  
51  1 Y 1 A LYS 322 ? CE  ? A LYS 115 CE  
52  1 Y 1 A LYS 322 ? NZ  ? A LYS 115 NZ  
53  1 Y 1 A LYS 327 ? CE  ? A LYS 120 CE  
54  1 Y 1 A LYS 327 ? NZ  ? A LYS 120 NZ  
55  1 Y 1 A LYS 335 ? CG  ? A LYS 128 CG  
56  1 Y 1 A LYS 335 ? CD  ? A LYS 128 CD  
57  1 Y 1 A LYS 335 ? CE  ? A LYS 128 CE  
58  1 Y 1 A LYS 335 ? NZ  ? A LYS 128 NZ  
59  1 Y 1 A LYS 355 ? CD  ? A LYS 148 CD  
60  1 Y 1 A LYS 355 ? CE  ? A LYS 148 CE  
61  1 Y 1 A LYS 355 ? NZ  ? A LYS 148 NZ  
62  1 Y 1 A LYS 358 ? CD  ? A LYS 151 CD  
63  1 Y 1 A LYS 358 ? CE  ? A LYS 151 CE  
64  1 Y 1 A LYS 358 ? NZ  ? A LYS 151 NZ  
65  1 Y 1 A LYS 378 ? CE  ? A LYS 171 CE  
66  1 Y 1 A LYS 378 ? NZ  ? A LYS 171 NZ  
67  1 Y 1 A ASP 416 ? CG  ? A ASP 209 CG  
68  1 Y 1 A ASP 416 ? OD1 ? A ASP 209 OD1 
69  1 Y 1 A ASP 416 ? OD2 ? A ASP 209 OD2 
70  1 Y 1 A GLN 417 ? CB  ? A GLN 210 CB  
71  1 Y 1 A GLN 417 ? CG  ? A GLN 210 CG  
72  1 Y 1 A GLN 417 ? CD  ? A GLN 210 CD  
73  1 Y 1 A GLN 417 ? OE1 ? A GLN 210 OE1 
74  1 Y 1 A GLN 417 ? NE2 ? A GLN 210 NE2 
75  1 Y 1 A ASN 418 ? CG  ? A ASN 211 CG  
76  1 Y 1 A ASN 418 ? OD1 ? A ASN 211 OD1 
77  1 Y 1 A ASN 418 ? ND2 ? A ASN 211 ND2 
78  1 Y 1 A LYS 439 ? CG  ? A LYS 232 CG  
79  1 Y 1 A LYS 439 ? CD  ? A LYS 232 CD  
80  1 Y 1 A LYS 439 ? CE  ? A LYS 232 CE  
81  1 Y 1 A LYS 439 ? NZ  ? A LYS 232 NZ  
82  1 Y 1 A LYS 443 ? CG  ? A LYS 236 CG  
83  1 Y 1 A LYS 443 ? CD  ? A LYS 236 CD  
84  1 Y 1 A LYS 443 ? CE  ? A LYS 236 CE  
85  1 Y 1 A LYS 443 ? NZ  ? A LYS 236 NZ  
86  1 Y 1 A ASN 460 ? CG  ? A ASN 253 CG  
87  1 Y 1 A ASN 460 ? OD1 ? A ASN 253 OD1 
88  1 Y 1 A ASN 460 ? ND2 ? A ASN 253 ND2 
89  1 Y 1 A HIS 461 ? CB  ? A HIS 254 CB  
90  1 Y 1 A HIS 461 ? CG  ? A HIS 254 CG  
91  1 Y 1 A HIS 461 ? ND1 ? A HIS 254 ND1 
92  1 Y 1 A HIS 461 ? CD2 ? A HIS 254 CD2 
93  1 Y 1 A HIS 461 ? CE1 ? A HIS 254 CE1 
94  1 Y 1 A HIS 461 ? NE2 ? A HIS 254 NE2 
95  1 Y 1 A LYS 472 ? CE  ? A LYS 265 CE  
96  1 Y 1 A LYS 472 ? NZ  ? A LYS 265 NZ  
97  1 Y 1 A LYS 476 ? CG  ? A LYS 269 CG  
98  1 Y 1 A LYS 476 ? CD  ? A LYS 269 CD  
99  1 Y 1 A LYS 476 ? CE  ? A LYS 269 CE  
100 1 Y 1 A LYS 476 ? NZ  ? A LYS 269 NZ  
101 1 Y 1 A ARG 487 ? CD  ? A ARG 280 CD  
102 1 Y 1 A ARG 487 ? NE  ? A ARG 280 NE  
103 1 Y 1 A ARG 487 ? CZ  ? A ARG 280 CZ  
104 1 Y 1 A ARG 487 ? NH1 ? A ARG 280 NH1 
105 1 Y 1 A ARG 487 ? NH2 ? A ARG 280 NH2 
106 1 Y 1 A GLN 538 ? CB  ? A GLN 331 CB  
107 1 Y 1 A GLN 538 ? CG  ? A GLN 331 CG  
108 1 Y 1 A GLN 538 ? CD  ? A GLN 331 CD  
109 1 Y 1 A GLN 538 ? OE1 ? A GLN 331 OE1 
110 1 Y 1 A GLN 538 ? NE2 ? A GLN 331 NE2 
111 1 Y 1 A GLU 542 ? CG  ? A GLU 335 CG  
112 1 Y 1 A GLU 542 ? CD  ? A GLU 335 CD  
113 1 Y 1 A GLU 542 ? OE1 ? A GLU 335 OE1 
114 1 Y 1 A GLU 542 ? OE2 ? A GLU 335 OE2 
115 1 Y 1 A ARG 543 ? CG  ? A ARG 336 CG  
116 1 Y 1 A ARG 543 ? CD  ? A ARG 336 CD  
117 1 Y 1 A ARG 543 ? NE  ? A ARG 336 NE  
118 1 Y 1 A ARG 543 ? CZ  ? A ARG 336 CZ  
119 1 Y 1 A ARG 543 ? NH1 ? A ARG 336 NH1 
120 1 Y 1 A ARG 543 ? NH2 ? A ARG 336 NH2 
121 1 Y 1 A LEU 544 ? CG  ? A LEU 337 CG  
122 1 Y 1 A LEU 544 ? CD1 ? A LEU 337 CD1 
123 1 Y 1 A LEU 544 ? CD2 ? A LEU 337 CD2 
124 1 Y 1 A GLN 545 ? CG  ? A GLN 338 CG  
125 1 Y 1 A GLN 545 ? CD  ? A GLN 338 CD  
126 1 Y 1 A GLN 545 ? OE1 ? A GLN 338 OE1 
127 1 Y 1 A GLN 545 ? NE2 ? A GLN 338 NE2 
128 1 Y 1 A GLU 546 ? CB  ? A GLU 339 CB  
129 1 Y 1 A GLU 546 ? CG  ? A GLU 339 CG  
130 1 Y 1 A GLU 546 ? CD  ? A GLU 339 CD  
131 1 Y 1 A GLU 546 ? OE1 ? A GLU 339 OE1 
132 1 Y 1 A GLU 546 ? OE2 ? A GLU 339 OE2 
133 1 Y 1 A GLU 547 ? CG  ? A GLU 340 CG  
134 1 Y 1 A GLU 547 ? CD  ? A GLU 340 CD  
135 1 Y 1 A GLU 547 ? OE1 ? A GLU 340 OE1 
136 1 Y 1 A GLU 547 ? OE2 ? A GLU 340 OE2 
137 1 Y 1 B LYS 48  ? CG  ? B LYS 48  CG  
138 1 Y 1 B LYS 48  ? CD  ? B LYS 48  CD  
139 1 Y 1 B LYS 48  ? CE  ? B LYS 48  CE  
140 1 Y 1 B LYS 48  ? NZ  ? B LYS 48  NZ  
141 1 Y 1 B ARG 54  ? CG  ? B ARG 54  CG  
142 1 Y 1 B ARG 54  ? CD  ? B ARG 54  CD  
143 1 Y 1 B ARG 54  ? NE  ? B ARG 54  NE  
144 1 Y 1 B ARG 54  ? CZ  ? B ARG 54  CZ  
145 1 Y 1 B ARG 54  ? NH1 ? B ARG 54  NH1 
146 1 Y 1 B ARG 54  ? NH2 ? B ARG 54  NH2 
147 1 Y 1 C PHE 233 ? CB  ? C PHE 26  CB  
148 1 Y 1 C PHE 233 ? CG  ? C PHE 26  CG  
149 1 Y 1 C PHE 233 ? CD1 ? C PHE 26  CD1 
150 1 Y 1 C PHE 233 ? CD2 ? C PHE 26  CD2 
151 1 Y 1 C PHE 233 ? CE1 ? C PHE 26  CE1 
152 1 Y 1 C PHE 233 ? CE2 ? C PHE 26  CE2 
153 1 Y 1 C PHE 233 ? CZ  ? C PHE 26  CZ  
154 1 Y 1 C LYS 240 ? CE  ? C LYS 33  CE  
155 1 Y 1 C LYS 240 ? NZ  ? C LYS 33  NZ  
156 1 Y 1 C MET 244 ? CG  ? C MET 37  CG  
157 1 Y 1 C MET 244 ? SD  ? C MET 37  SD  
158 1 Y 1 C MET 244 ? CE  ? C MET 37  CE  
159 1 Y 1 C LYS 254 ? CB  ? C LYS 47  CB  
160 1 Y 1 C LYS 254 ? CG  ? C LYS 47  CG  
161 1 Y 1 C LYS 254 ? CD  ? C LYS 47  CD  
162 1 Y 1 C LYS 254 ? CE  ? C LYS 47  CE  
163 1 Y 1 C LYS 254 ? NZ  ? C LYS 47  NZ  
164 1 Y 1 C LEU 258 ? CB  ? C LEU 51  CB  
165 1 Y 1 C LEU 258 ? CG  ? C LEU 51  CG  
166 1 Y 1 C LEU 258 ? CD1 ? C LEU 51  CD1 
167 1 Y 1 C LEU 258 ? CD2 ? C LEU 51  CD2 
168 1 Y 1 C ARG 262 ? CD  ? C ARG 55  CD  
169 1 Y 1 C ARG 262 ? NE  ? C ARG 55  NE  
170 1 Y 1 C ARG 262 ? CZ  ? C ARG 55  CZ  
171 1 Y 1 C ARG 262 ? NH1 ? C ARG 55  NH1 
172 1 Y 1 C ARG 262 ? NH2 ? C ARG 55  NH2 
173 1 Y 1 C LEU 267 ? CB  ? C LEU 60  CB  
174 1 Y 1 C LEU 267 ? CG  ? C LEU 60  CG  
175 1 Y 1 C LEU 267 ? CD1 ? C LEU 60  CD1 
176 1 Y 1 C LEU 267 ? CD2 ? C LEU 60  CD2 
177 1 Y 1 C LYS 272 ? CB  ? C LYS 65  CB  
178 1 Y 1 C LYS 272 ? CG  ? C LYS 65  CG  
179 1 Y 1 C LYS 272 ? CD  ? C LYS 65  CD  
180 1 Y 1 C LYS 272 ? CE  ? C LYS 65  CE  
181 1 Y 1 C LYS 272 ? NZ  ? C LYS 65  NZ  
182 1 Y 1 C LYS 277 ? CB  ? C LYS 70  CB  
183 1 Y 1 C LYS 277 ? CG  ? C LYS 70  CG  
184 1 Y 1 C LYS 277 ? CD  ? C LYS 70  CD  
185 1 Y 1 C LYS 277 ? CE  ? C LYS 70  CE  
186 1 Y 1 C LYS 277 ? NZ  ? C LYS 70  NZ  
187 1 Y 1 C LYS 278 ? CB  ? C LYS 71  CB  
188 1 Y 1 C LYS 278 ? CG  ? C LYS 71  CG  
189 1 Y 1 C LYS 278 ? CD  ? C LYS 71  CD  
190 1 Y 1 C LYS 278 ? CE  ? C LYS 71  CE  
191 1 Y 1 C LYS 278 ? NZ  ? C LYS 71  NZ  
192 1 Y 1 C LYS 281 ? CD  ? C LYS 74  CD  
193 1 Y 1 C LYS 281 ? CE  ? C LYS 74  CE  
194 1 Y 1 C LYS 281 ? NZ  ? C LYS 74  NZ  
195 1 Y 1 C GLU 286 ? CB  ? C GLU 79  CB  
196 1 Y 1 C GLU 286 ? CG  ? C GLU 79  CG  
197 1 Y 1 C GLU 286 ? CD  ? C GLU 79  CD  
198 1 Y 1 C GLU 286 ? OE1 ? C GLU 79  OE1 
199 1 Y 1 C GLU 286 ? OE2 ? C GLU 79  OE2 
200 1 Y 1 C LEU 288 ? CG  ? C LEU 81  CG  
201 1 Y 1 C LEU 288 ? CD1 ? C LEU 81  CD1 
202 1 Y 1 C LEU 288 ? CD2 ? C LEU 81  CD2 
203 1 Y 1 C GLN 293 ? CG  ? C GLN 86  CG  
204 1 Y 1 C GLN 293 ? CD  ? C GLN 86  CD  
205 1 Y 1 C GLN 293 ? OE1 ? C GLN 86  OE1 
206 1 Y 1 C GLN 293 ? NE2 ? C GLN 86  NE2 
207 1 Y 1 C LYS 310 ? CG  ? C LYS 103 CG  
208 1 Y 1 C LYS 310 ? CD  ? C LYS 103 CD  
209 1 Y 1 C LYS 310 ? CE  ? C LYS 103 CE  
210 1 Y 1 C LYS 310 ? NZ  ? C LYS 103 NZ  
211 1 Y 1 C LYS 322 ? CD  ? C LYS 115 CD  
212 1 Y 1 C LYS 322 ? CE  ? C LYS 115 CE  
213 1 Y 1 C LYS 322 ? NZ  ? C LYS 115 NZ  
214 1 Y 1 C LYS 327 ? CE  ? C LYS 120 CE  
215 1 Y 1 C LYS 327 ? NZ  ? C LYS 120 NZ  
216 1 Y 1 C LYS 355 ? CG  ? C LYS 148 CG  
217 1 Y 1 C LYS 355 ? CD  ? C LYS 148 CD  
218 1 Y 1 C LYS 355 ? CE  ? C LYS 148 CE  
219 1 Y 1 C LYS 355 ? NZ  ? C LYS 148 NZ  
220 1 Y 1 C LYS 358 ? CD  ? C LYS 151 CD  
221 1 Y 1 C LYS 358 ? CE  ? C LYS 151 CE  
222 1 Y 1 C LYS 358 ? NZ  ? C LYS 151 NZ  
223 1 Y 1 C LYS 378 ? CD  ? C LYS 171 CD  
224 1 Y 1 C LYS 378 ? CE  ? C LYS 171 CE  
225 1 Y 1 C LYS 378 ? NZ  ? C LYS 171 NZ  
226 1 Y 1 C GLU 383 ? CD  ? C GLU 176 CD  
227 1 Y 1 C GLU 383 ? OE1 ? C GLU 176 OE1 
228 1 Y 1 C GLU 383 ? OE2 ? C GLU 176 OE2 
229 1 Y 1 C LYS 394 ? CE  ? C LYS 187 CE  
230 1 Y 1 C LYS 394 ? NZ  ? C LYS 187 NZ  
231 1 Y 1 C TYR 411 ? CG  ? C TYR 204 CG  
232 1 Y 1 C TYR 411 ? CD1 ? C TYR 204 CD1 
233 1 Y 1 C TYR 411 ? CD2 ? C TYR 204 CD2 
234 1 Y 1 C TYR 411 ? CE1 ? C TYR 204 CE1 
235 1 Y 1 C TYR 411 ? CE2 ? C TYR 204 CE2 
236 1 Y 1 C TYR 411 ? CZ  ? C TYR 204 CZ  
237 1 Y 1 C TYR 411 ? OH  ? C TYR 204 OH  
238 1 Y 1 C ASP 416 ? CB  ? C ASP 209 CB  
239 1 Y 1 C ASP 416 ? CG  ? C ASP 209 CG  
240 1 Y 1 C ASP 416 ? OD1 ? C ASP 209 OD1 
241 1 Y 1 C ASP 416 ? OD2 ? C ASP 209 OD2 
242 1 Y 1 C GLN 417 ? CB  ? C GLN 210 CB  
243 1 Y 1 C GLN 417 ? CG  ? C GLN 210 CG  
244 1 Y 1 C GLN 417 ? CD  ? C GLN 210 CD  
245 1 Y 1 C GLN 417 ? OE1 ? C GLN 210 OE1 
246 1 Y 1 C GLN 417 ? NE2 ? C GLN 210 NE2 
247 1 Y 1 C ASN 418 ? CB  ? C ASN 211 CB  
248 1 Y 1 C ASN 418 ? CG  ? C ASN 211 CG  
249 1 Y 1 C ASN 418 ? OD1 ? C ASN 211 OD1 
250 1 Y 1 C ASN 418 ? ND2 ? C ASN 211 ND2 
251 1 Y 1 C ARG 424 ? CG  ? C ARG 217 CG  
252 1 Y 1 C ARG 424 ? CD  ? C ARG 217 CD  
253 1 Y 1 C ARG 424 ? NE  ? C ARG 217 NE  
254 1 Y 1 C ARG 424 ? CZ  ? C ARG 217 CZ  
255 1 Y 1 C ARG 424 ? NH1 ? C ARG 217 NH1 
256 1 Y 1 C ARG 424 ? NH2 ? C ARG 217 NH2 
257 1 Y 1 C LYS 443 ? CG  ? C LYS 236 CG  
258 1 Y 1 C LYS 443 ? CD  ? C LYS 236 CD  
259 1 Y 1 C LYS 443 ? CE  ? C LYS 236 CE  
260 1 Y 1 C LYS 443 ? NZ  ? C LYS 236 NZ  
261 1 Y 1 C ASN 460 ? CG  ? C ASN 253 CG  
262 1 Y 1 C ASN 460 ? OD1 ? C ASN 253 OD1 
263 1 Y 1 C ASN 460 ? ND2 ? C ASN 253 ND2 
264 1 Y 1 C HIS 461 ? CG  ? C HIS 254 CG  
265 1 Y 1 C HIS 461 ? ND1 ? C HIS 254 ND1 
266 1 Y 1 C HIS 461 ? CD2 ? C HIS 254 CD2 
267 1 Y 1 C HIS 461 ? CE1 ? C HIS 254 CE1 
268 1 Y 1 C HIS 461 ? NE2 ? C HIS 254 NE2 
269 1 Y 1 C LYS 476 ? CB  ? C LYS 269 CB  
270 1 Y 1 C LYS 476 ? CG  ? C LYS 269 CG  
271 1 Y 1 C LYS 476 ? CD  ? C LYS 269 CD  
272 1 Y 1 C LYS 476 ? CE  ? C LYS 269 CE  
273 1 Y 1 C LYS 476 ? NZ  ? C LYS 269 NZ  
274 1 Y 1 C GLU 491 ? CG  ? C GLU 284 CG  
275 1 Y 1 C GLU 491 ? CD  ? C GLU 284 CD  
276 1 Y 1 C GLU 491 ? OE1 ? C GLU 284 OE1 
277 1 Y 1 C GLU 491 ? OE2 ? C GLU 284 OE2 
278 1 Y 1 C GLU 492 ? CB  ? C GLU 285 CB  
279 1 Y 1 C GLU 492 ? CG  ? C GLU 285 CG  
280 1 Y 1 C GLU 492 ? CD  ? C GLU 285 CD  
281 1 Y 1 C GLU 492 ? OE1 ? C GLU 285 OE1 
282 1 Y 1 C GLU 492 ? OE2 ? C GLU 285 OE2 
283 1 Y 1 C GLN 538 ? CB  ? C GLN 331 CB  
284 1 Y 1 C GLN 538 ? CG  ? C GLN 331 CG  
285 1 Y 1 C GLN 538 ? CD  ? C GLN 331 CD  
286 1 Y 1 C GLN 538 ? OE1 ? C GLN 331 OE1 
287 1 Y 1 C GLN 538 ? NE2 ? C GLN 331 NE2 
288 1 Y 1 C GLN 539 ? CB  ? C GLN 332 CB  
289 1 Y 1 C GLN 539 ? CG  ? C GLN 332 CG  
290 1 Y 1 C GLN 539 ? CD  ? C GLN 332 CD  
291 1 Y 1 C GLN 539 ? OE1 ? C GLN 332 OE1 
292 1 Y 1 C GLN 539 ? NE2 ? C GLN 332 NE2 
293 1 Y 1 C GLU 542 ? CB  ? C GLU 335 CB  
294 1 Y 1 C GLU 542 ? CG  ? C GLU 335 CG  
295 1 Y 1 C GLU 542 ? CD  ? C GLU 335 CD  
296 1 Y 1 C GLU 542 ? OE1 ? C GLU 335 OE1 
297 1 Y 1 C GLU 542 ? OE2 ? C GLU 335 OE2 
298 1 Y 1 C ARG 543 ? CG  ? C ARG 336 CG  
299 1 Y 1 C ARG 543 ? CD  ? C ARG 336 CD  
300 1 Y 1 C ARG 543 ? NE  ? C ARG 336 NE  
301 1 Y 1 C ARG 543 ? CZ  ? C ARG 336 CZ  
302 1 Y 1 C ARG 543 ? NH1 ? C ARG 336 NH1 
303 1 Y 1 C ARG 543 ? NH2 ? C ARG 336 NH2 
304 1 Y 1 C LEU 544 ? CB  ? C LEU 337 CB  
305 1 Y 1 C LEU 544 ? CG  ? C LEU 337 CG  
306 1 Y 1 C LEU 544 ? CD1 ? C LEU 337 CD1 
307 1 Y 1 C LEU 544 ? CD2 ? C LEU 337 CD2 
308 1 Y 1 C GLU 546 ? CB  ? C GLU 339 CB  
309 1 Y 1 C GLU 546 ? CG  ? C GLU 339 CG  
310 1 Y 1 C GLU 546 ? CD  ? C GLU 339 CD  
311 1 Y 1 C GLU 546 ? OE1 ? C GLU 339 OE1 
312 1 Y 1 C GLU 546 ? OE2 ? C GLU 339 OE2 
313 1 Y 1 C GLU 547 ? CB  ? C GLU 340 CB  
314 1 Y 1 C GLU 547 ? CG  ? C GLU 340 CG  
315 1 Y 1 C GLU 547 ? CD  ? C GLU 340 CD  
316 1 Y 1 C GLU 547 ? OE1 ? C GLU 340 OE1 
317 1 Y 1 C GLU 547 ? OE2 ? C GLU 340 OE2 
318 1 Y 1 C LYS 548 ? CG  ? C LYS 341 CG  
319 1 Y 1 C LYS 548 ? CD  ? C LYS 341 CD  
320 1 Y 1 C LYS 548 ? CE  ? C LYS 341 CE  
321 1 Y 1 C LYS 548 ? NZ  ? C LYS 341 NZ  
322 1 Y 1 C ARG 549 ? CG  ? C ARG 342 CG  
323 1 Y 1 C ARG 549 ? CD  ? C ARG 342 CD  
324 1 Y 1 C ARG 549 ? NE  ? C ARG 342 NE  
325 1 Y 1 C ARG 549 ? CZ  ? C ARG 342 CZ  
326 1 Y 1 C ARG 549 ? NH1 ? C ARG 342 NH1 
327 1 Y 1 C ARG 549 ? NH2 ? C ARG 342 NH2 
328 1 Y 1 C GLU 551 ? CG  ? C GLU 344 CG  
329 1 Y 1 C GLU 551 ? CD  ? C GLU 344 CD  
330 1 Y 1 C GLU 551 ? OE1 ? C GLU 344 OE1 
331 1 Y 1 C GLU 551 ? OE2 ? C GLU 344 OE2 
332 1 Y 1 D LYS 6   ? CE  ? D LYS 6   CE  
333 1 Y 1 D LYS 6   ? NZ  ? D LYS 6   NZ  
334 1 Y 1 D LYS 11  ? CG  ? D LYS 11  CG  
335 1 Y 1 D LYS 11  ? CD  ? D LYS 11  CD  
336 1 Y 1 D LYS 11  ? CE  ? D LYS 11  CE  
337 1 Y 1 D LYS 11  ? NZ  ? D LYS 11  NZ  
338 1 Y 1 D LYS 48  ? CG  ? D LYS 48  CG  
339 1 Y 1 D LYS 48  ? CD  ? D LYS 48  CD  
340 1 Y 1 D LYS 48  ? CE  ? D LYS 48  CE  
341 1 Y 1 D LYS 48  ? NZ  ? D LYS 48  NZ  
342 1 Y 1 D ARG 54  ? CZ  ? D ARG 54  CZ  
343 1 Y 1 D ARG 54  ? NH1 ? D ARG 54  NH1 
344 1 Y 1 D ARG 54  ? NH2 ? D ARG 54  NH2 
345 1 Y 1 E LYS 240 ? CD  ? E LYS 33  CD  
346 1 Y 1 E LYS 240 ? CE  ? E LYS 33  CE  
347 1 Y 1 E LYS 240 ? NZ  ? E LYS 33  NZ  
348 1 Y 1 E GLU 248 ? CB  ? E GLU 41  CB  
349 1 Y 1 E GLU 248 ? CG  ? E GLU 41  CG  
350 1 Y 1 E GLU 248 ? CD  ? E GLU 41  CD  
351 1 Y 1 E GLU 248 ? OE1 ? E GLU 41  OE1 
352 1 Y 1 E GLU 248 ? OE2 ? E GLU 41  OE2 
353 1 Y 1 E ASP 250 ? CG  ? E ASP 43  CG  
354 1 Y 1 E ASP 250 ? OD1 ? E ASP 43  OD1 
355 1 Y 1 E ASP 250 ? OD2 ? E ASP 43  OD2 
356 1 Y 1 E LYS 254 ? CB  ? E LYS 47  CB  
357 1 Y 1 E LYS 254 ? CG  ? E LYS 47  CG  
358 1 Y 1 E LYS 254 ? CD  ? E LYS 47  CD  
359 1 Y 1 E LYS 254 ? CE  ? E LYS 47  CE  
360 1 Y 1 E LYS 254 ? NZ  ? E LYS 47  NZ  
361 1 Y 1 E LEU 258 ? CG  ? E LEU 51  CG  
362 1 Y 1 E LEU 258 ? CD1 ? E LEU 51  CD1 
363 1 Y 1 E LEU 258 ? CD2 ? E LEU 51  CD2 
364 1 Y 1 E GLN 261 ? CG  ? E GLN 54  CG  
365 1 Y 1 E GLN 261 ? CD  ? E GLN 54  CD  
366 1 Y 1 E GLN 261 ? OE1 ? E GLN 54  OE1 
367 1 Y 1 E GLN 261 ? NE2 ? E GLN 54  NE2 
368 1 Y 1 E ARG 262 ? CZ  ? E ARG 55  CZ  
369 1 Y 1 E ARG 262 ? NH1 ? E ARG 55  NH1 
370 1 Y 1 E ARG 262 ? NH2 ? E ARG 55  NH2 
371 1 Y 1 E GLN 268 ? CB  ? E GLN 61  CB  
372 1 Y 1 E GLN 268 ? CG  ? E GLN 61  CG  
373 1 Y 1 E GLN 268 ? CD  ? E GLN 61  CD  
374 1 Y 1 E GLN 268 ? OE1 ? E GLN 61  OE1 
375 1 Y 1 E GLN 268 ? NE2 ? E GLN 61  NE2 
376 1 Y 1 E ASP 271 ? CG  ? E ASP 64  CG  
377 1 Y 1 E ASP 271 ? OD1 ? E ASP 64  OD1 
378 1 Y 1 E ASP 271 ? OD2 ? E ASP 64  OD2 
379 1 Y 1 E LYS 272 ? CG  ? E LYS 65  CG  
380 1 Y 1 E LYS 272 ? CD  ? E LYS 65  CD  
381 1 Y 1 E LYS 272 ? CE  ? E LYS 65  CE  
382 1 Y 1 E LYS 272 ? NZ  ? E LYS 65  NZ  
383 1 Y 1 E LYS 277 ? CG  ? E LYS 70  CG  
384 1 Y 1 E LYS 277 ? CD  ? E LYS 70  CD  
385 1 Y 1 E LYS 277 ? CE  ? E LYS 70  CE  
386 1 Y 1 E LYS 277 ? NZ  ? E LYS 70  NZ  
387 1 Y 1 E LYS 278 ? CG  ? E LYS 71  CG  
388 1 Y 1 E LYS 278 ? CD  ? E LYS 71  CD  
389 1 Y 1 E LYS 278 ? CE  ? E LYS 71  CE  
390 1 Y 1 E LYS 278 ? NZ  ? E LYS 71  NZ  
391 1 Y 1 E LYS 281 ? CG  ? E LYS 74  CG  
392 1 Y 1 E LYS 281 ? CD  ? E LYS 74  CD  
393 1 Y 1 E LYS 281 ? CE  ? E LYS 74  CE  
394 1 Y 1 E LYS 281 ? NZ  ? E LYS 74  NZ  
395 1 Y 1 E LYS 310 ? CB  ? E LYS 103 CB  
396 1 Y 1 E LYS 310 ? CG  ? E LYS 103 CG  
397 1 Y 1 E LYS 310 ? CD  ? E LYS 103 CD  
398 1 Y 1 E LYS 310 ? CE  ? E LYS 103 CE  
399 1 Y 1 E LYS 310 ? NZ  ? E LYS 103 NZ  
400 1 Y 1 E LYS 312 ? CB  ? E LYS 105 CB  
401 1 Y 1 E LYS 312 ? CG  ? E LYS 105 CG  
402 1 Y 1 E LYS 312 ? CD  ? E LYS 105 CD  
403 1 Y 1 E LYS 312 ? CE  ? E LYS 105 CE  
404 1 Y 1 E LYS 312 ? NZ  ? E LYS 105 NZ  
405 1 Y 1 E LYS 322 ? CD  ? E LYS 115 CD  
406 1 Y 1 E LYS 322 ? CE  ? E LYS 115 CE  
407 1 Y 1 E LYS 322 ? NZ  ? E LYS 115 NZ  
408 1 Y 1 E LYS 327 ? CE  ? E LYS 120 CE  
409 1 Y 1 E LYS 327 ? NZ  ? E LYS 120 NZ  
410 1 Y 1 E LYS 355 ? CB  ? E LYS 148 CB  
411 1 Y 1 E LYS 355 ? CG  ? E LYS 148 CG  
412 1 Y 1 E LYS 355 ? CD  ? E LYS 148 CD  
413 1 Y 1 E LYS 355 ? CE  ? E LYS 148 CE  
414 1 Y 1 E LYS 355 ? NZ  ? E LYS 148 NZ  
415 1 Y 1 E LYS 358 ? CG  ? E LYS 151 CG  
416 1 Y 1 E LYS 358 ? CD  ? E LYS 151 CD  
417 1 Y 1 E LYS 358 ? CE  ? E LYS 151 CE  
418 1 Y 1 E LYS 358 ? NZ  ? E LYS 151 NZ  
419 1 Y 1 E LYS 378 ? CD  ? E LYS 171 CD  
420 1 Y 1 E LYS 378 ? CE  ? E LYS 171 CE  
421 1 Y 1 E LYS 378 ? NZ  ? E LYS 171 NZ  
422 1 Y 1 E GLU 383 ? CG  ? E GLU 176 CG  
423 1 Y 1 E GLU 383 ? CD  ? E GLU 176 CD  
424 1 Y 1 E GLU 383 ? OE1 ? E GLU 176 OE1 
425 1 Y 1 E GLU 383 ? OE2 ? E GLU 176 OE2 
426 1 Y 1 E LYS 391 ? CG  ? E LYS 184 CG  
427 1 Y 1 E LYS 391 ? CD  ? E LYS 184 CD  
428 1 Y 1 E LYS 391 ? CE  ? E LYS 184 CE  
429 1 Y 1 E LYS 391 ? NZ  ? E LYS 184 NZ  
430 1 Y 1 E GLN 417 ? CG  ? E GLN 210 CG  
431 1 Y 1 E GLN 417 ? CD  ? E GLN 210 CD  
432 1 Y 1 E GLN 417 ? OE1 ? E GLN 210 OE1 
433 1 Y 1 E GLN 417 ? NE2 ? E GLN 210 NE2 
434 1 Y 1 E ASN 418 ? CG  ? E ASN 211 CG  
435 1 Y 1 E ASN 418 ? OD1 ? E ASN 211 OD1 
436 1 Y 1 E ASN 418 ? ND2 ? E ASN 211 ND2 
437 1 Y 1 E GLU 426 ? CG  ? E GLU 219 CG  
438 1 Y 1 E GLU 426 ? CD  ? E GLU 219 CD  
439 1 Y 1 E GLU 426 ? OE1 ? E GLU 219 OE1 
440 1 Y 1 E GLU 426 ? OE2 ? E GLU 219 OE2 
441 1 Y 1 E LYS 443 ? CG  ? E LYS 236 CG  
442 1 Y 1 E LYS 443 ? CD  ? E LYS 236 CD  
443 1 Y 1 E LYS 443 ? CE  ? E LYS 236 CE  
444 1 Y 1 E LYS 443 ? NZ  ? E LYS 236 NZ  
445 1 Y 1 E HIS 461 ? CB  ? E HIS 254 CB  
446 1 Y 1 E HIS 461 ? CG  ? E HIS 254 CG  
447 1 Y 1 E HIS 461 ? ND1 ? E HIS 254 ND1 
448 1 Y 1 E HIS 461 ? CD2 ? E HIS 254 CD2 
449 1 Y 1 E HIS 461 ? CE1 ? E HIS 254 CE1 
450 1 Y 1 E HIS 461 ? NE2 ? E HIS 254 NE2 
451 1 Y 1 E LYS 472 ? CG  ? E LYS 265 CG  
452 1 Y 1 E LYS 472 ? CD  ? E LYS 265 CD  
453 1 Y 1 E LYS 472 ? CE  ? E LYS 265 CE  
454 1 Y 1 E LYS 472 ? NZ  ? E LYS 265 NZ  
455 1 Y 1 E LYS 476 ? CG  ? E LYS 269 CG  
456 1 Y 1 E LYS 476 ? CD  ? E LYS 269 CD  
457 1 Y 1 E LYS 476 ? CE  ? E LYS 269 CE  
458 1 Y 1 E LYS 476 ? NZ  ? E LYS 269 NZ  
459 1 Y 1 E LYS 479 ? CG  ? E LYS 272 CG  
460 1 Y 1 E LYS 479 ? CD  ? E LYS 272 CD  
461 1 Y 1 E LYS 479 ? CE  ? E LYS 272 CE  
462 1 Y 1 E LYS 479 ? NZ  ? E LYS 272 NZ  
463 1 Y 1 E ARG 487 ? CG  ? E ARG 280 CG  
464 1 Y 1 E ARG 487 ? CD  ? E ARG 280 CD  
465 1 Y 1 E ARG 487 ? NE  ? E ARG 280 NE  
466 1 Y 1 E ARG 487 ? CZ  ? E ARG 280 CZ  
467 1 Y 1 E ARG 487 ? NH1 ? E ARG 280 NH1 
468 1 Y 1 E ARG 487 ? NH2 ? E ARG 280 NH2 
469 1 Y 1 E LYS 490 ? CG  ? E LYS 283 CG  
470 1 Y 1 E LYS 490 ? CD  ? E LYS 283 CD  
471 1 Y 1 E LYS 490 ? CE  ? E LYS 283 CE  
472 1 Y 1 E LYS 490 ? NZ  ? E LYS 283 NZ  
473 1 Y 1 E GLU 491 ? CB  ? E GLU 284 CB  
474 1 Y 1 E GLU 491 ? CG  ? E GLU 284 CG  
475 1 Y 1 E GLU 491 ? CD  ? E GLU 284 CD  
476 1 Y 1 E GLU 491 ? OE1 ? E GLU 284 OE1 
477 1 Y 1 E GLU 491 ? OE2 ? E GLU 284 OE2 
478 1 Y 1 E ARG 508 ? CG  ? E ARG 301 CG  
479 1 Y 1 E ARG 508 ? CD  ? E ARG 301 CD  
480 1 Y 1 E ARG 508 ? NE  ? E ARG 301 NE  
481 1 Y 1 E ARG 508 ? CZ  ? E ARG 301 CZ  
482 1 Y 1 E ARG 508 ? NH1 ? E ARG 301 NH1 
483 1 Y 1 E ARG 508 ? NH2 ? E ARG 301 NH2 
484 1 Y 1 E HIS 509 ? CG  ? E HIS 302 CG  
485 1 Y 1 E HIS 509 ? ND1 ? E HIS 302 ND1 
486 1 Y 1 E HIS 509 ? CD2 ? E HIS 302 CD2 
487 1 Y 1 E HIS 509 ? CE1 ? E HIS 302 CE1 
488 1 Y 1 E HIS 509 ? NE2 ? E HIS 302 NE2 
489 1 Y 1 E HIS 534 ? CG  ? E HIS 327 CG  
490 1 Y 1 E HIS 534 ? ND1 ? E HIS 327 ND1 
491 1 Y 1 E HIS 534 ? CD2 ? E HIS 327 CD2 
492 1 Y 1 E HIS 534 ? CE1 ? E HIS 327 CE1 
493 1 Y 1 E HIS 534 ? NE2 ? E HIS 327 NE2 
494 1 Y 1 E GLN 538 ? CB  ? E GLN 331 CB  
495 1 Y 1 E GLN 538 ? CG  ? E GLN 331 CG  
496 1 Y 1 E GLN 538 ? CD  ? E GLN 331 CD  
497 1 Y 1 E GLN 538 ? OE1 ? E GLN 331 OE1 
498 1 Y 1 E GLN 538 ? NE2 ? E GLN 331 NE2 
499 1 Y 1 E LEU 540 ? CB  ? E LEU 333 CB  
500 1 Y 1 E LEU 540 ? CG  ? E LEU 333 CG  
501 1 Y 1 E LEU 540 ? CD1 ? E LEU 333 CD1 
502 1 Y 1 E LEU 540 ? CD2 ? E LEU 333 CD2 
503 1 Y 1 E VAL 541 ? CB  ? E VAL 334 CB  
504 1 Y 1 E VAL 541 ? CG1 ? E VAL 334 CG1 
505 1 Y 1 E VAL 541 ? CG2 ? E VAL 334 CG2 
506 1 Y 1 E GLU 542 ? CB  ? E GLU 335 CB  
507 1 Y 1 E GLU 542 ? CG  ? E GLU 335 CG  
508 1 Y 1 E GLU 542 ? CD  ? E GLU 335 CD  
509 1 Y 1 E GLU 542 ? OE1 ? E GLU 335 OE1 
510 1 Y 1 E GLU 542 ? OE2 ? E GLU 335 OE2 
511 1 Y 1 E ARG 543 ? CB  ? E ARG 336 CB  
512 1 Y 1 E ARG 543 ? CG  ? E ARG 336 CG  
513 1 Y 1 E ARG 543 ? CD  ? E ARG 336 CD  
514 1 Y 1 E ARG 543 ? NE  ? E ARG 336 NE  
515 1 Y 1 E ARG 543 ? CZ  ? E ARG 336 CZ  
516 1 Y 1 E ARG 543 ? NH1 ? E ARG 336 NH1 
517 1 Y 1 E ARG 543 ? NH2 ? E ARG 336 NH2 
518 1 Y 1 E LEU 544 ? CB  ? E LEU 337 CB  
519 1 Y 1 E LEU 544 ? CG  ? E LEU 337 CG  
520 1 Y 1 E LEU 544 ? CD1 ? E LEU 337 CD1 
521 1 Y 1 E LEU 544 ? CD2 ? E LEU 337 CD2 
522 1 Y 1 E GLN 545 ? CB  ? E GLN 338 CB  
523 1 Y 1 E GLN 545 ? CG  ? E GLN 338 CG  
524 1 Y 1 E GLN 545 ? CD  ? E GLN 338 CD  
525 1 Y 1 E GLN 545 ? OE1 ? E GLN 338 OE1 
526 1 Y 1 E GLN 545 ? NE2 ? E GLN 338 NE2 
527 1 Y 1 E GLU 546 ? CB  ? E GLU 339 CB  
528 1 Y 1 E GLU 546 ? CG  ? E GLU 339 CG  
529 1 Y 1 E GLU 546 ? CD  ? E GLU 339 CD  
530 1 Y 1 E GLU 546 ? OE1 ? E GLU 339 OE1 
531 1 Y 1 E GLU 546 ? OE2 ? E GLU 339 OE2 
532 1 Y 1 E GLU 547 ? CG  ? E GLU 340 CG  
533 1 Y 1 E GLU 547 ? CD  ? E GLU 340 CD  
534 1 Y 1 E GLU 547 ? OE1 ? E GLU 340 OE1 
535 1 Y 1 E GLU 547 ? OE2 ? E GLU 340 OE2 
536 1 Y 1 F LYS 11  ? CG  ? F LYS 11  CG  
537 1 Y 1 F LYS 11  ? CD  ? F LYS 11  CD  
538 1 Y 1 F LYS 11  ? CE  ? F LYS 11  CE  
539 1 Y 1 F LYS 11  ? NZ  ? F LYS 11  NZ  
540 1 Y 1 F LYS 48  ? CD  ? F LYS 48  CD  
541 1 Y 1 F LYS 48  ? CE  ? F LYS 48  CE  
542 1 Y 1 F LYS 48  ? NZ  ? F LYS 48  NZ  
543 1 Y 1 G LEU 216 ? CB  ? G LEU 9   CB  
544 1 Y 1 G LEU 216 ? CG  ? G LEU 9   CG  
545 1 Y 1 G LEU 216 ? CD1 ? G LEU 9   CD1 
546 1 Y 1 G LEU 216 ? CD2 ? G LEU 9   CD2 
547 1 Y 1 G GLN 219 ? CG  ? G GLN 12  CG  
548 1 Y 1 G GLN 219 ? CD  ? G GLN 12  CD  
549 1 Y 1 G GLN 219 ? OE1 ? G GLN 12  OE1 
550 1 Y 1 G GLN 219 ? NE2 ? G GLN 12  NE2 
551 1 Y 1 G GLN 230 ? CB  ? G GLN 23  CB  
552 1 Y 1 G GLN 230 ? CG  ? G GLN 23  CG  
553 1 Y 1 G GLN 230 ? CD  ? G GLN 23  CD  
554 1 Y 1 G GLN 230 ? OE1 ? G GLN 23  OE1 
555 1 Y 1 G GLN 230 ? NE2 ? G GLN 23  NE2 
556 1 Y 1 G PHE 233 ? CB  ? G PHE 26  CB  
557 1 Y 1 G PHE 233 ? CG  ? G PHE 26  CG  
558 1 Y 1 G PHE 233 ? CD1 ? G PHE 26  CD1 
559 1 Y 1 G PHE 233 ? CD2 ? G PHE 26  CD2 
560 1 Y 1 G PHE 233 ? CE1 ? G PHE 26  CE1 
561 1 Y 1 G PHE 233 ? CE2 ? G PHE 26  CE2 
562 1 Y 1 G PHE 233 ? CZ  ? G PHE 26  CZ  
563 1 Y 1 G PHE 234 ? CB  ? G PHE 27  CB  
564 1 Y 1 G PHE 234 ? CG  ? G PHE 27  CG  
565 1 Y 1 G PHE 234 ? CD1 ? G PHE 27  CD1 
566 1 Y 1 G PHE 234 ? CD2 ? G PHE 27  CD2 
567 1 Y 1 G PHE 234 ? CE1 ? G PHE 27  CE1 
568 1 Y 1 G PHE 234 ? CE2 ? G PHE 27  CE2 
569 1 Y 1 G PHE 234 ? CZ  ? G PHE 27  CZ  
570 1 Y 1 G GLN 237 ? CB  ? G GLN 30  CB  
571 1 Y 1 G GLN 237 ? CG  ? G GLN 30  CG  
572 1 Y 1 G GLN 237 ? CD  ? G GLN 30  CD  
573 1 Y 1 G GLN 237 ? OE1 ? G GLN 30  OE1 
574 1 Y 1 G GLN 237 ? NE2 ? G GLN 30  NE2 
575 1 Y 1 G ARG 239 ? CB  ? G ARG 32  CB  
576 1 Y 1 G ARG 239 ? CG  ? G ARG 32  CG  
577 1 Y 1 G ARG 239 ? CD  ? G ARG 32  CD  
578 1 Y 1 G ARG 239 ? NE  ? G ARG 32  NE  
579 1 Y 1 G ARG 239 ? CZ  ? G ARG 32  CZ  
580 1 Y 1 G ARG 239 ? NH1 ? G ARG 32  NH1 
581 1 Y 1 G ARG 239 ? NH2 ? G ARG 32  NH2 
582 1 Y 1 G LYS 240 ? CB  ? G LYS 33  CB  
583 1 Y 1 G LYS 240 ? CG  ? G LYS 33  CG  
584 1 Y 1 G LYS 240 ? CD  ? G LYS 33  CD  
585 1 Y 1 G LYS 240 ? CE  ? G LYS 33  CE  
586 1 Y 1 G LYS 240 ? NZ  ? G LYS 33  NZ  
587 1 Y 1 G MET 244 ? CB  ? G MET 37  CB  
588 1 Y 1 G MET 244 ? CG  ? G MET 37  CG  
589 1 Y 1 G MET 244 ? SD  ? G MET 37  SD  
590 1 Y 1 G MET 244 ? CE  ? G MET 37  CE  
591 1 Y 1 G GLU 248 ? CG  ? G GLU 41  CG  
592 1 Y 1 G GLU 248 ? CD  ? G GLU 41  CD  
593 1 Y 1 G GLU 248 ? OE1 ? G GLU 41  OE1 
594 1 Y 1 G GLU 248 ? OE2 ? G GLU 41  OE2 
595 1 Y 1 G LYS 254 ? CB  ? G LYS 47  CB  
596 1 Y 1 G LYS 254 ? CG  ? G LYS 47  CG  
597 1 Y 1 G LYS 254 ? CD  ? G LYS 47  CD  
598 1 Y 1 G LYS 254 ? CE  ? G LYS 47  CE  
599 1 Y 1 G LYS 254 ? NZ  ? G LYS 47  NZ  
600 1 Y 1 G LEU 258 ? CG  ? G LEU 51  CG  
601 1 Y 1 G LEU 258 ? CD1 ? G LEU 51  CD1 
602 1 Y 1 G LEU 258 ? CD2 ? G LEU 51  CD2 
603 1 Y 1 G GLN 261 ? CB  ? G GLN 54  CB  
604 1 Y 1 G GLN 261 ? CG  ? G GLN 54  CG  
605 1 Y 1 G GLN 261 ? CD  ? G GLN 54  CD  
606 1 Y 1 G GLN 261 ? OE1 ? G GLN 54  OE1 
607 1 Y 1 G GLN 261 ? NE2 ? G GLN 54  NE2 
608 1 Y 1 G ARG 262 ? CG  ? G ARG 55  CG  
609 1 Y 1 G ARG 262 ? CD  ? G ARG 55  CD  
610 1 Y 1 G ARG 262 ? NE  ? G ARG 55  NE  
611 1 Y 1 G ARG 262 ? CZ  ? G ARG 55  CZ  
612 1 Y 1 G ARG 262 ? NH1 ? G ARG 55  NH1 
613 1 Y 1 G ARG 262 ? NH2 ? G ARG 55  NH2 
614 1 Y 1 G TYR 265 ? CG  ? G TYR 58  CG  
615 1 Y 1 G TYR 265 ? CD1 ? G TYR 58  CD1 
616 1 Y 1 G TYR 265 ? CD2 ? G TYR 58  CD2 
617 1 Y 1 G TYR 265 ? CE1 ? G TYR 58  CE1 
618 1 Y 1 G TYR 265 ? CE2 ? G TYR 58  CE2 
619 1 Y 1 G TYR 265 ? CZ  ? G TYR 58  CZ  
620 1 Y 1 G TYR 265 ? OH  ? G TYR 58  OH  
621 1 Y 1 G GLU 266 ? CB  ? G GLU 59  CB  
622 1 Y 1 G GLU 266 ? CG  ? G GLU 59  CG  
623 1 Y 1 G GLU 266 ? CD  ? G GLU 59  CD  
624 1 Y 1 G GLU 266 ? OE1 ? G GLU 59  OE1 
625 1 Y 1 G GLU 266 ? OE2 ? G GLU 59  OE2 
626 1 Y 1 G LEU 267 ? CB  ? G LEU 60  CB  
627 1 Y 1 G LEU 267 ? CG  ? G LEU 60  CG  
628 1 Y 1 G LEU 267 ? CD1 ? G LEU 60  CD1 
629 1 Y 1 G LEU 267 ? CD2 ? G LEU 60  CD2 
630 1 Y 1 G GLN 268 ? CB  ? G GLN 61  CB  
631 1 Y 1 G GLN 268 ? CG  ? G GLN 61  CG  
632 1 Y 1 G GLN 268 ? CD  ? G GLN 61  CD  
633 1 Y 1 G GLN 268 ? OE1 ? G GLN 61  OE1 
634 1 Y 1 G GLN 268 ? NE2 ? G GLN 61  NE2 
635 1 Y 1 G ASP 271 ? CB  ? G ASP 64  CB  
636 1 Y 1 G ASP 271 ? CG  ? G ASP 64  CG  
637 1 Y 1 G ASP 271 ? OD1 ? G ASP 64  OD1 
638 1 Y 1 G ASP 271 ? OD2 ? G ASP 64  OD2 
639 1 Y 1 G LYS 272 ? CG  ? G LYS 65  CG  
640 1 Y 1 G LYS 272 ? CD  ? G LYS 65  CD  
641 1 Y 1 G LYS 272 ? CE  ? G LYS 65  CE  
642 1 Y 1 G LYS 272 ? NZ  ? G LYS 65  NZ  
643 1 Y 1 G LYS 278 ? CB  ? G LYS 71  CB  
644 1 Y 1 G LYS 278 ? CG  ? G LYS 71  CG  
645 1 Y 1 G LYS 278 ? CD  ? G LYS 71  CD  
646 1 Y 1 G LYS 278 ? CE  ? G LYS 71  CE  
647 1 Y 1 G LYS 278 ? NZ  ? G LYS 71  NZ  
648 1 Y 1 G LYS 281 ? CB  ? G LYS 74  CB  
649 1 Y 1 G LYS 281 ? CG  ? G LYS 74  CG  
650 1 Y 1 G LYS 281 ? CD  ? G LYS 74  CD  
651 1 Y 1 G LYS 281 ? CE  ? G LYS 74  CE  
652 1 Y 1 G LYS 281 ? NZ  ? G LYS 74  NZ  
653 1 Y 1 G LYS 310 ? CB  ? G LYS 103 CB  
654 1 Y 1 G LYS 310 ? CG  ? G LYS 103 CG  
655 1 Y 1 G LYS 310 ? CD  ? G LYS 103 CD  
656 1 Y 1 G LYS 310 ? CE  ? G LYS 103 CE  
657 1 Y 1 G LYS 310 ? NZ  ? G LYS 103 NZ  
658 1 Y 1 G LYS 312 ? CB  ? G LYS 105 CB  
659 1 Y 1 G LYS 312 ? CG  ? G LYS 105 CG  
660 1 Y 1 G LYS 312 ? CD  ? G LYS 105 CD  
661 1 Y 1 G LYS 312 ? CE  ? G LYS 105 CE  
662 1 Y 1 G LYS 312 ? NZ  ? G LYS 105 NZ  
663 1 Y 1 G CYS 315 ? SG  ? G CYS 108 SG  
664 1 Y 1 G LYS 322 ? CG  ? G LYS 115 CG  
665 1 Y 1 G LYS 322 ? CD  ? G LYS 115 CD  
666 1 Y 1 G LYS 322 ? CE  ? G LYS 115 CE  
667 1 Y 1 G LYS 322 ? NZ  ? G LYS 115 NZ  
668 1 Y 1 G ARG 325 ? CD  ? G ARG 118 CD  
669 1 Y 1 G ARG 325 ? NE  ? G ARG 118 NE  
670 1 Y 1 G ARG 325 ? CZ  ? G ARG 118 CZ  
671 1 Y 1 G ARG 325 ? NH1 ? G ARG 118 NH1 
672 1 Y 1 G ARG 325 ? NH2 ? G ARG 118 NH2 
673 1 Y 1 G LYS 327 ? CE  ? G LYS 120 CE  
674 1 Y 1 G LYS 327 ? NZ  ? G LYS 120 NZ  
675 1 Y 1 G LYS 335 ? CG  ? G LYS 128 CG  
676 1 Y 1 G LYS 335 ? CD  ? G LYS 128 CD  
677 1 Y 1 G LYS 335 ? CE  ? G LYS 128 CE  
678 1 Y 1 G LYS 335 ? NZ  ? G LYS 128 NZ  
679 1 Y 1 G GLU 336 ? CB  ? G GLU 129 CB  
680 1 Y 1 G GLU 336 ? CG  ? G GLU 129 CG  
681 1 Y 1 G GLU 336 ? CD  ? G GLU 129 CD  
682 1 Y 1 G GLU 336 ? OE1 ? G GLU 129 OE1 
683 1 Y 1 G GLU 336 ? OE2 ? G GLU 129 OE2 
684 1 Y 1 G LYS 355 ? CD  ? G LYS 148 CD  
685 1 Y 1 G LYS 355 ? CE  ? G LYS 148 CE  
686 1 Y 1 G LYS 355 ? NZ  ? G LYS 148 NZ  
687 1 Y 1 G LYS 357 ? CG  ? G LYS 150 CG  
688 1 Y 1 G LYS 357 ? CD  ? G LYS 150 CD  
689 1 Y 1 G LYS 357 ? CE  ? G LYS 150 CE  
690 1 Y 1 G LYS 357 ? NZ  ? G LYS 150 NZ  
691 1 Y 1 G LYS 358 ? CG  ? G LYS 151 CG  
692 1 Y 1 G LYS 358 ? CD  ? G LYS 151 CD  
693 1 Y 1 G LYS 358 ? CE  ? G LYS 151 CE  
694 1 Y 1 G LYS 358 ? NZ  ? G LYS 151 NZ  
695 1 Y 1 G PHE 361 ? CB  ? G PHE 154 CB  
696 1 Y 1 G PHE 361 ? CG  ? G PHE 154 CG  
697 1 Y 1 G PHE 361 ? CD1 ? G PHE 154 CD1 
698 1 Y 1 G PHE 361 ? CD2 ? G PHE 154 CD2 
699 1 Y 1 G PHE 361 ? CE1 ? G PHE 154 CE1 
700 1 Y 1 G PHE 361 ? CE2 ? G PHE 154 CE2 
701 1 Y 1 G PHE 361 ? CZ  ? G PHE 154 CZ  
702 1 Y 1 G LYS 378 ? CG  ? G LYS 171 CG  
703 1 Y 1 G LYS 378 ? CD  ? G LYS 171 CD  
704 1 Y 1 G LYS 378 ? CE  ? G LYS 171 CE  
705 1 Y 1 G LYS 378 ? NZ  ? G LYS 171 NZ  
706 1 Y 1 G GLU 383 ? CB  ? G GLU 176 CB  
707 1 Y 1 G GLU 383 ? CG  ? G GLU 176 CG  
708 1 Y 1 G GLU 383 ? CD  ? G GLU 176 CD  
709 1 Y 1 G GLU 383 ? OE1 ? G GLU 176 OE1 
710 1 Y 1 G GLU 383 ? OE2 ? G GLU 176 OE2 
711 1 Y 1 G GLU 388 ? CG  ? G GLU 181 CG  
712 1 Y 1 G GLU 388 ? CD  ? G GLU 181 CD  
713 1 Y 1 G GLU 388 ? OE1 ? G GLU 181 OE1 
714 1 Y 1 G GLU 388 ? OE2 ? G GLU 181 OE2 
715 1 Y 1 G GLU 390 ? CB  ? G GLU 183 CB  
716 1 Y 1 G GLU 390 ? CG  ? G GLU 183 CG  
717 1 Y 1 G GLU 390 ? CD  ? G GLU 183 CD  
718 1 Y 1 G GLU 390 ? OE1 ? G GLU 183 OE1 
719 1 Y 1 G GLU 390 ? OE2 ? G GLU 183 OE2 
720 1 Y 1 G LEU 406 ? CB  ? G LEU 199 CB  
721 1 Y 1 G LEU 406 ? CG  ? G LEU 199 CG  
722 1 Y 1 G LEU 406 ? CD1 ? G LEU 199 CD1 
723 1 Y 1 G LEU 406 ? CD2 ? G LEU 199 CD2 
724 1 Y 1 G MET 410 ? CG  ? G MET 203 CG  
725 1 Y 1 G MET 410 ? SD  ? G MET 203 SD  
726 1 Y 1 G MET 410 ? CE  ? G MET 203 CE  
727 1 Y 1 G ASP 412 ? CB  ? G ASP 205 CB  
728 1 Y 1 G ASP 412 ? CG  ? G ASP 205 CG  
729 1 Y 1 G ASP 412 ? OD1 ? G ASP 205 OD1 
730 1 Y 1 G ASP 412 ? OD2 ? G ASP 205 OD2 
731 1 Y 1 G ASN 418 ? CG  ? G ASN 211 CG  
732 1 Y 1 G ASN 418 ? OD1 ? G ASN 211 OD1 
733 1 Y 1 G ASN 418 ? ND2 ? G ASN 211 ND2 
734 1 Y 1 G ARG 424 ? CB  ? G ARG 217 CB  
735 1 Y 1 G ARG 424 ? CG  ? G ARG 217 CG  
736 1 Y 1 G ARG 424 ? CD  ? G ARG 217 CD  
737 1 Y 1 G ARG 424 ? NE  ? G ARG 217 NE  
738 1 Y 1 G ARG 424 ? CZ  ? G ARG 217 CZ  
739 1 Y 1 G ARG 424 ? NH1 ? G ARG 217 NH1 
740 1 Y 1 G ARG 424 ? NH2 ? G ARG 217 NH2 
741 1 Y 1 G GLU 426 ? CB  ? G GLU 219 CB  
742 1 Y 1 G GLU 426 ? CG  ? G GLU 219 CG  
743 1 Y 1 G GLU 426 ? CD  ? G GLU 219 CD  
744 1 Y 1 G GLU 426 ? OE1 ? G GLU 219 OE1 
745 1 Y 1 G GLU 426 ? OE2 ? G GLU 219 OE2 
746 1 Y 1 G GLU 429 ? CG  ? G GLU 222 CG  
747 1 Y 1 G GLU 429 ? CD  ? G GLU 222 CD  
748 1 Y 1 G GLU 429 ? OE1 ? G GLU 222 OE1 
749 1 Y 1 G GLU 429 ? OE2 ? G GLU 222 OE2 
750 1 Y 1 G GLN 430 ? CB  ? G GLN 223 CB  
751 1 Y 1 G GLN 430 ? CG  ? G GLN 223 CG  
752 1 Y 1 G GLN 430 ? CD  ? G GLN 223 CD  
753 1 Y 1 G GLN 430 ? OE1 ? G GLN 223 OE1 
754 1 Y 1 G GLN 430 ? NE2 ? G GLN 223 NE2 
755 1 Y 1 G LYS 443 ? CG  ? G LYS 236 CG  
756 1 Y 1 G LYS 443 ? CD  ? G LYS 236 CD  
757 1 Y 1 G LYS 443 ? CE  ? G LYS 236 CE  
758 1 Y 1 G LYS 443 ? NZ  ? G LYS 236 NZ  
759 1 Y 1 G TYR 448 ? CB  ? G TYR 241 CB  
760 1 Y 1 G TYR 448 ? CG  ? G TYR 241 CG  
761 1 Y 1 G TYR 448 ? CD1 ? G TYR 241 CD1 
762 1 Y 1 G TYR 448 ? CD2 ? G TYR 241 CD2 
763 1 Y 1 G TYR 448 ? CE1 ? G TYR 241 CE1 
764 1 Y 1 G TYR 448 ? CE2 ? G TYR 241 CE2 
765 1 Y 1 G TYR 448 ? CZ  ? G TYR 241 CZ  
766 1 Y 1 G TYR 448 ? OH  ? G TYR 241 OH  
767 1 Y 1 G TYR 468 ? CB  ? G TYR 261 CB  
768 1 Y 1 G TYR 468 ? CG  ? G TYR 261 CG  
769 1 Y 1 G TYR 468 ? CD1 ? G TYR 261 CD1 
770 1 Y 1 G TYR 468 ? CD2 ? G TYR 261 CD2 
771 1 Y 1 G TYR 468 ? CE1 ? G TYR 261 CE1 
772 1 Y 1 G TYR 468 ? CE2 ? G TYR 261 CE2 
773 1 Y 1 G TYR 468 ? CZ  ? G TYR 261 CZ  
774 1 Y 1 G TYR 468 ? OH  ? G TYR 261 OH  
775 1 Y 1 G LYS 472 ? CB  ? G LYS 265 CB  
776 1 Y 1 G LYS 472 ? CG  ? G LYS 265 CG  
777 1 Y 1 G LYS 472 ? CD  ? G LYS 265 CD  
778 1 Y 1 G LYS 472 ? CE  ? G LYS 265 CE  
779 1 Y 1 G LYS 472 ? NZ  ? G LYS 265 NZ  
780 1 Y 1 G LYS 476 ? CB  ? G LYS 269 CB  
781 1 Y 1 G LYS 476 ? CG  ? G LYS 269 CG  
782 1 Y 1 G LYS 476 ? CD  ? G LYS 269 CD  
783 1 Y 1 G LYS 476 ? CE  ? G LYS 269 CE  
784 1 Y 1 G LYS 476 ? NZ  ? G LYS 269 NZ  
785 1 Y 1 G TRP 477 ? CB  ? G TRP 270 CB  
786 1 Y 1 G TRP 477 ? CG  ? G TRP 270 CG  
787 1 Y 1 G TRP 477 ? CD1 ? G TRP 270 CD1 
788 1 Y 1 G TRP 477 ? CD2 ? G TRP 270 CD2 
789 1 Y 1 G TRP 477 ? NE1 ? G TRP 270 NE1 
790 1 Y 1 G TRP 477 ? CE2 ? G TRP 270 CE2 
791 1 Y 1 G TRP 477 ? CE3 ? G TRP 270 CE3 
792 1 Y 1 G TRP 477 ? CZ2 ? G TRP 270 CZ2 
793 1 Y 1 G TRP 477 ? CZ3 ? G TRP 270 CZ3 
794 1 Y 1 G TRP 477 ? CH2 ? G TRP 270 CH2 
795 1 Y 1 G LYS 479 ? CD  ? G LYS 272 CD  
796 1 Y 1 G LYS 479 ? CE  ? G LYS 272 CE  
797 1 Y 1 G LYS 479 ? NZ  ? G LYS 272 NZ  
798 1 Y 1 G PHE 480 ? CB  ? G PHE 273 CB  
799 1 Y 1 G PHE 480 ? CG  ? G PHE 273 CG  
800 1 Y 1 G PHE 480 ? CD1 ? G PHE 273 CD1 
801 1 Y 1 G PHE 480 ? CD2 ? G PHE 273 CD2 
802 1 Y 1 G PHE 480 ? CE1 ? G PHE 273 CE1 
803 1 Y 1 G PHE 480 ? CE2 ? G PHE 273 CE2 
804 1 Y 1 G PHE 480 ? CZ  ? G PHE 273 CZ  
805 1 Y 1 G ARG 487 ? CG  ? G ARG 280 CG  
806 1 Y 1 G ARG 487 ? CD  ? G ARG 280 CD  
807 1 Y 1 G ARG 487 ? NE  ? G ARG 280 NE  
808 1 Y 1 G ARG 487 ? CZ  ? G ARG 280 CZ  
809 1 Y 1 G ARG 487 ? NH1 ? G ARG 280 NH1 
810 1 Y 1 G ARG 487 ? NH2 ? G ARG 280 NH2 
811 1 Y 1 G LYS 490 ? CB  ? G LYS 283 CB  
812 1 Y 1 G LYS 490 ? CG  ? G LYS 283 CG  
813 1 Y 1 G LYS 490 ? CD  ? G LYS 283 CD  
814 1 Y 1 G LYS 490 ? CE  ? G LYS 283 CE  
815 1 Y 1 G LYS 490 ? NZ  ? G LYS 283 NZ  
816 1 Y 1 G GLU 491 ? CB  ? G GLU 284 CB  
817 1 Y 1 G GLU 491 ? CG  ? G GLU 284 CG  
818 1 Y 1 G GLU 491 ? CD  ? G GLU 284 CD  
819 1 Y 1 G GLU 491 ? OE1 ? G GLU 284 OE1 
820 1 Y 1 G GLU 491 ? OE2 ? G GLU 284 OE2 
821 1 Y 1 G GLU 495 ? CG  ? G GLU 288 CG  
822 1 Y 1 G GLU 495 ? CD  ? G GLU 288 CD  
823 1 Y 1 G GLU 495 ? OE1 ? G GLU 288 OE1 
824 1 Y 1 G GLU 495 ? OE2 ? G GLU 288 OE2 
825 1 Y 1 G HIS 496 ? CB  ? G HIS 289 CB  
826 1 Y 1 G HIS 496 ? CG  ? G HIS 289 CG  
827 1 Y 1 G HIS 496 ? ND1 ? G HIS 289 ND1 
828 1 Y 1 G HIS 496 ? CD2 ? G HIS 289 CD2 
829 1 Y 1 G HIS 496 ? CE1 ? G HIS 289 CE1 
830 1 Y 1 G HIS 496 ? NE2 ? G HIS 289 NE2 
831 1 Y 1 G ARG 508 ? CB  ? G ARG 301 CB  
832 1 Y 1 G ARG 508 ? CG  ? G ARG 301 CG  
833 1 Y 1 G ARG 508 ? CD  ? G ARG 301 CD  
834 1 Y 1 G ARG 508 ? NE  ? G ARG 301 NE  
835 1 Y 1 G ARG 508 ? CZ  ? G ARG 301 CZ  
836 1 Y 1 G ARG 508 ? NH1 ? G ARG 301 NH1 
837 1 Y 1 G ARG 508 ? NH2 ? G ARG 301 NH2 
838 1 Y 1 G HIS 509 ? CG  ? G HIS 302 CG  
839 1 Y 1 G HIS 509 ? ND1 ? G HIS 302 ND1 
840 1 Y 1 G HIS 509 ? CD2 ? G HIS 302 CD2 
841 1 Y 1 G HIS 509 ? CE1 ? G HIS 302 CE1 
842 1 Y 1 G HIS 509 ? NE2 ? G HIS 302 NE2 
843 1 Y 1 G LYS 523 ? CD  ? G LYS 316 CD  
844 1 Y 1 G LYS 523 ? CE  ? G LYS 316 CE  
845 1 Y 1 G LYS 523 ? NZ  ? G LYS 316 NZ  
846 1 Y 1 G LEU 524 ? CG  ? G LEU 317 CG  
847 1 Y 1 G LEU 524 ? CD1 ? G LEU 317 CD1 
848 1 Y 1 G LEU 524 ? CD2 ? G LEU 317 CD2 
849 1 Y 1 G LEU 528 ? CB  ? G LEU 321 CB  
850 1 Y 1 G LEU 528 ? CG  ? G LEU 321 CG  
851 1 Y 1 G LEU 528 ? CD1 ? G LEU 321 CD1 
852 1 Y 1 G LEU 528 ? CD2 ? G LEU 321 CD2 
853 1 Y 1 H LYS 6   ? CG  ? H LYS 6   CG  
854 1 Y 1 H LYS 6   ? CD  ? H LYS 6   CD  
855 1 Y 1 H LYS 6   ? CE  ? H LYS 6   CE  
856 1 Y 1 H LYS 6   ? NZ  ? H LYS 6   NZ  
857 1 Y 1 H LYS 11  ? CG  ? H LYS 11  CG  
858 1 Y 1 H LYS 11  ? CD  ? H LYS 11  CD  
859 1 Y 1 H LYS 11  ? CE  ? H LYS 11  CE  
860 1 Y 1 H LYS 11  ? NZ  ? H LYS 11  NZ  
861 1 Y 1 H GLN 40  ? CB  ? H GLN 40  CB  
862 1 Y 1 H GLN 40  ? CG  ? H GLN 40  CG  
863 1 Y 1 H GLN 40  ? CD  ? H GLN 40  CD  
864 1 Y 1 H GLN 40  ? OE1 ? H GLN 40  OE1 
865 1 Y 1 H GLN 40  ? NE2 ? H GLN 40  NE2 
866 1 Y 1 H LYS 48  ? CD  ? H LYS 48  CD  
867 1 Y 1 H LYS 48  ? CE  ? H LYS 48  CE  
868 1 Y 1 H LYS 48  ? NZ  ? H LYS 48  NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? '(1.16_3549: ???)' 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .                  2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .                  3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? .                  4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.21 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9IJU 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     100.640 
_cell.length_a_esd                 ? 
_cell.length_b                     84.860 
_cell.length_b_esd                 ? 
_cell.length_c                     106.780 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9IJU 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9IJU 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.30 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          46.50 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M Bis-tris pH 6.5, 0.2 M MgCl2, 25% PEG3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     80 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-07-02 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9792 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL02U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9792 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL02U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9IJU 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.46 
_reflns.d_resolution_low                               20.581 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     65312 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.55 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.84 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.04516 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.46 
_reflns_shell.d_res_low                                     2.548 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             6466 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.6319 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9IJU 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.460 
_refine.ls_d_res_low                             20.581 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     65263 
_refine.ls_number_reflns_R_free                  3263 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.74 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2208 
_refine.ls_R_factor_R_free                       0.2702 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2180 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      1NB8 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.11 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 31.69 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.38 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.460 
_refine_hist.d_res_low                        20.581 
_refine_hist.number_atoms_solvent             65 
_refine_hist.number_atoms_total               11957 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        11852 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         40 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009 ? 12123 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.990 ? 16420 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 5.545 ? 7142  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.054 ? 1824  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.006 ? 2166  ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.4600 2.4967 . . 120 2709 99.00  . . . . 0.3190 . . . . . . . . . . . 0.3737 
'X-RAY DIFFRACTION' 2.4967 2.5356 . . 113 2732 100.00 . . . . 0.2994 . . . . . . . . . . . 0.3390 
'X-RAY DIFFRACTION' 2.5356 2.5771 . . 104 2704 99.00  . . . . 0.2895 . . . . . . . . . . . 0.3899 
'X-RAY DIFFRACTION' 2.5771 2.6215 . . 146 2646 100.00 . . . . 0.2846 . . . . . . . . . . . 0.3151 
'X-RAY DIFFRACTION' 2.6215 2.6690 . . 148 2706 100.00 . . . . 0.2904 . . . . . . . . . . . 0.3282 
'X-RAY DIFFRACTION' 2.6690 2.7203 . . 144 2649 100.00 . . . . 0.2794 . . . . . . . . . . . 0.3297 
'X-RAY DIFFRACTION' 2.7203 2.7757 . . 144 2691 100.00 . . . . 0.2817 . . . . . . . . . . . 0.3860 
'X-RAY DIFFRACTION' 2.7757 2.8359 . . 141 2664 100.00 . . . . 0.2635 . . . . . . . . . . . 0.3285 
'X-RAY DIFFRACTION' 2.8359 2.9017 . . 132 2689 100.00 . . . . 0.2574 . . . . . . . . . . . 0.3098 
'X-RAY DIFFRACTION' 2.9017 2.9740 . . 140 2687 100.00 . . . . 0.2569 . . . . . . . . . . . 0.3171 
'X-RAY DIFFRACTION' 2.9740 3.0542 . . 136 2707 100.00 . . . . 0.2598 . . . . . . . . . . . 0.3167 
'X-RAY DIFFRACTION' 3.0542 3.1437 . . 151 2694 100.00 . . . . 0.2619 . . . . . . . . . . . 0.3270 
'X-RAY DIFFRACTION' 3.1437 3.2448 . . 121 2706 100.00 . . . . 0.2467 . . . . . . . . . . . 0.3287 
'X-RAY DIFFRACTION' 3.2448 3.3603 . . 152 2663 100.00 . . . . 0.2452 . . . . . . . . . . . 0.3188 
'X-RAY DIFFRACTION' 3.3603 3.4943 . . 131 2704 100.00 . . . . 0.2393 . . . . . . . . . . . 0.2876 
'X-RAY DIFFRACTION' 3.4943 3.6525 . . 130 2727 100.00 . . . . 0.2338 . . . . . . . . . . . 0.2947 
'X-RAY DIFFRACTION' 3.6525 3.8438 . . 123 2707 100.00 . . . . 0.2201 . . . . . . . . . . . 0.2974 
'X-RAY DIFFRACTION' 3.8438 4.0829 . . 167 2686 100.00 . . . . 0.1979 . . . . . . . . . . . 0.2323 
'X-RAY DIFFRACTION' 4.0829 4.3953 . . 179 2683 100.00 . . . . 0.1777 . . . . . . . . . . . 0.2347 
'X-RAY DIFFRACTION' 4.3953 4.8325 . . 147 2700 100.00 . . . . 0.1628 . . . . . . . . . . . 0.2291 
'X-RAY DIFFRACTION' 4.8325 5.5199 . . 180 2684 100.00 . . . . 0.1804 . . . . . . . . . . . 0.2230 
'X-RAY DIFFRACTION' 5.5199 6.9105 . . 136 2744 100.00 . . . . 0.2176 . . . . . . . . . . . 0.2680 
'X-RAY DIFFRACTION' 6.9105 20.581 . . 178 2718 98.00  . . . . 0.1879 . . . . . . . . . . . 0.2367 
# 
_struct.entry_id                     9IJU 
_struct.title                        
'Sertraline enhances the deubiquitinase activity of USP7 by binding to its switching loop region' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9IJU 
_struct_keywords.text            'ubiquitin specific protease, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 1 ? 
F N N 2 ? 
G N N 1 ? 
H N N 2 ? 
I N N 3 ? 
J N N 3 ? 
K N N 4 ? 
L N N 4 ? 
M N N 4 ? 
N N N 4 ? 
O N N 4 ? 
P N N 4 ? 
Q N N 4 ? 
R N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP UBP7_HUMAN  Q93009 ? 1 
;KKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWET
LDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDY
VAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN
YILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEV
LQAVTDHDIPQQLVERLQEEKRIEAQKRKERQE
;
208 
2 UNP RS27A_HUMAN P62979 ? 2 MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRG 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9IJU A 1 ? 353 ? Q93009 208 ? 560 ? 208 560 
2 2 9IJU B 1 ? 75  ? P62979 1   ? 75  ? 1   75  
3 1 9IJU C 1 ? 353 ? Q93009 208 ? 560 ? 208 560 
4 2 9IJU D 1 ? 75  ? P62979 1   ? 75  ? 1   75  
5 1 9IJU E 1 ? 353 ? Q93009 208 ? 560 ? 208 560 
6 2 9IJU F 1 ? 75  ? P62979 1   ? 75  ? 1   75  
7 1 9IJU G 1 ? 353 ? Q93009 208 ? 560 ? 208 560 
8 2 9IJU H 1 ? 75  ? P62979 1   ? 75  ? 1   75  
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
3 author_and_software_defined_assembly PISA dimeric 2 
4 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 3430  ? 
1 MORE         -7    ? 
1 'SSA (A^2)'  16270 ? 
2 'ABSA (A^2)' 3210  ? 
2 MORE         -7    ? 
2 'SSA (A^2)'  16510 ? 
3 'ABSA (A^2)' 3280  ? 
3 MORE         -7    ? 
3 'SSA (A^2)'  16260 ? 
4 'ABSA (A^2)' 3250  ? 
4 MORE         -7    ? 
4 'SSA (A^2)'  15520 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,K,L   
2 1 C,D,I,M,N 
3 1 E,F,O,P   
4 1 G,H,J,Q,R 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'gel filtration' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 15  ? PHE A 27  ? THR A 222 PHE A 234 1 ? 13 
HELX_P HELX_P2  AA2 THR A 28  ? MET A 37  ? THR A 235 MET A 244 1 ? 10 
HELX_P HELX_P3  AA3 SER A 48  ? SER A 63  ? SER A 255 SER A 270 1 ? 16 
HELX_P HELX_P4  AA4 THR A 69  ? GLY A 77  ? THR A 276 GLY A 284 1 ? 9  
HELX_P HELX_P5  AA5 GLU A 79  ? MET A 85  ? GLU A 286 MET A 292 5 ? 7  
HELX_P HELX_P6  AA6 ASP A 88  ? LYS A 105 ? ASP A 295 LYS A 312 1 ? 18 
HELX_P HELX_P7  AA7 GLY A 111 ? ARG A 118 ? GLY A 318 ARG A 325 1 ? 8  
HELX_P HELX_P8  AA8 ASN A 152 ? ALA A 162 ? ASN A 359 ALA A 369 1 ? 11 
HELX_P HELX_P9  AA9 ASP A 167 ? LYS A 171 ? ASP A 374 LYS A 378 5 ? 5  
HELX_P HELX_P10 AB1 GLY A 175 ? HIS A 177 ? GLY A 382 HIS A 384 5 ? 3  
HELX_P HELX_P11 AB2 ASP A 227 ? LEU A 230 ? ASP A 434 LEU A 437 5 ? 4  
HELX_P HELX_P12 AB3 THR A 282 ? ILE A 287 ? THR A 489 ILE A 494 1 ? 6  
HELX_P HELX_P13 AB4 GLU A 288 ? TYR A 291 ? GLU A 495 TYR A 498 5 ? 4  
HELX_P HELX_P14 AB5 LYS A 316 ? LEU A 321 ? LYS A 523 LEU A 528 1 ? 6  
HELX_P HELX_P15 AB6 THR A 325 ? ILE A 329 ? THR A 532 ILE A 536 5 ? 5  
HELX_P HELX_P16 AB7 PRO A 330 ? GLU A 339 ? PRO A 537 GLU A 546 1 ? 10 
HELX_P HELX_P17 AB8 THR B 22  ? GLY B 35  ? THR B 22  GLY B 35  1 ? 14 
HELX_P HELX_P18 AB9 PRO B 37  ? GLN B 41  ? PRO B 37  GLN B 41  5 ? 5  
HELX_P HELX_P19 AC1 LEU B 56  ? ASN B 60  ? LEU B 56  ASN B 60  5 ? 5  
HELX_P HELX_P20 AC2 THR C 15  ? PHE C 27  ? THR C 222 PHE C 234 1 ? 13 
HELX_P HELX_P21 AC3 THR C 28  ? MET C 37  ? THR C 235 MET C 244 1 ? 10 
HELX_P HELX_P22 AC4 SER C 48  ? SER C 63  ? SER C 255 SER C 270 1 ? 16 
HELX_P HELX_P23 AC5 THR C 69  ? GLY C 77  ? THR C 276 GLY C 284 1 ? 9  
HELX_P HELX_P24 AC6 GLU C 79  ? MET C 85  ? GLU C 286 MET C 292 5 ? 7  
HELX_P HELX_P25 AC7 ASP C 88  ? MET C 104 ? ASP C 295 MET C 311 1 ? 17 
HELX_P HELX_P26 AC8 GLY C 111 ? ARG C 118 ? GLY C 318 ARG C 325 1 ? 8  
HELX_P HELX_P27 AC9 ASN C 152 ? ALA C 162 ? ASN C 359 ALA C 369 1 ? 11 
HELX_P HELX_P28 AD1 ASP C 167 ? LYS C 171 ? ASP C 374 LYS C 378 5 ? 5  
HELX_P HELX_P29 AD2 GLY C 175 ? HIS C 177 ? GLY C 382 HIS C 384 5 ? 3  
HELX_P HELX_P30 AD3 ASP C 227 ? LEU C 230 ? ASP C 434 LEU C 437 5 ? 4  
HELX_P HELX_P31 AD4 THR C 282 ? ILE C 287 ? THR C 489 ILE C 494 1 ? 6  
HELX_P HELX_P32 AD5 GLU C 288 ? TYR C 291 ? GLU C 495 TYR C 498 5 ? 4  
HELX_P HELX_P33 AD6 LYS C 316 ? LEU C 321 ? LYS C 523 LEU C 528 1 ? 6  
HELX_P HELX_P34 AD7 THR C 325 ? ILE C 329 ? THR C 532 ILE C 536 5 ? 5  
HELX_P HELX_P35 AD8 PRO C 330 ? ARG C 342 ? PRO C 537 ARG C 549 1 ? 13 
HELX_P HELX_P36 AD9 THR D 22  ? GLY D 35  ? THR D 22  GLY D 35  1 ? 14 
HELX_P HELX_P37 AE1 PRO D 37  ? GLN D 41  ? PRO D 37  GLN D 41  5 ? 5  
HELX_P HELX_P38 AE2 THR D 55  ? ASN D 60  ? THR D 55  ASN D 60  5 ? 6  
HELX_P HELX_P39 AE3 THR E 15  ? PHE E 27  ? THR E 222 PHE E 234 1 ? 13 
HELX_P HELX_P40 AE4 THR E 28  ? MET E 37  ? THR E 235 MET E 244 1 ? 10 
HELX_P HELX_P41 AE5 SER E 48  ? SER E 63  ? SER E 255 SER E 270 1 ? 16 
HELX_P HELX_P42 AE6 THR E 69  ? PHE E 76  ? THR E 276 PHE E 283 1 ? 8  
HELX_P HELX_P43 AE7 GLU E 79  ? MET E 85  ? GLU E 286 MET E 292 5 ? 7  
HELX_P HELX_P44 AE8 ASP E 88  ? MET E 104 ? ASP E 295 MET E 311 1 ? 17 
HELX_P HELX_P45 AE9 GLY E 111 ? ARG E 118 ? GLY E 318 ARG E 325 1 ? 8  
HELX_P HELX_P46 AF1 ASN E 152 ? VAL E 161 ? ASN E 359 VAL E 368 1 ? 10 
HELX_P HELX_P47 AF2 ASP E 167 ? LYS E 171 ? ASP E 374 LYS E 378 5 ? 5  
HELX_P HELX_P48 AF3 GLY E 175 ? HIS E 177 ? GLY E 382 HIS E 384 5 ? 3  
HELX_P HELX_P49 AF4 ASP E 227 ? LEU E 230 ? ASP E 434 LEU E 437 5 ? 4  
HELX_P HELX_P50 AF5 THR E 282 ? ILE E 287 ? THR E 489 ILE E 494 1 ? 6  
HELX_P HELX_P51 AF6 GLU E 288 ? GLY E 292 ? GLU E 495 GLY E 499 5 ? 5  
HELX_P HELX_P52 AF7 LYS E 316 ? LEU E 321 ? LYS E 523 LEU E 528 1 ? 6  
HELX_P HELX_P53 AF8 PRO E 330 ? LEU E 337 ? PRO E 537 LEU E 544 1 ? 8  
HELX_P HELX_P54 AF9 THR F 22  ? GLY F 35  ? THR F 22  GLY F 35  1 ? 14 
HELX_P HELX_P55 AG1 PRO F 37  ? GLN F 41  ? PRO F 37  GLN F 41  5 ? 5  
HELX_P HELX_P56 AG2 LEU F 56  ? ASN F 60  ? LEU F 56  ASN F 60  5 ? 5  
HELX_P HELX_P57 AG3 THR G 15  ? PHE G 27  ? THR G 222 PHE G 234 1 ? 13 
HELX_P HELX_P58 AG4 THR G 28  ? MET G 38  ? THR G 235 MET G 245 1 ? 11 
HELX_P HELX_P59 AG5 SER G 48  ? GLN G 61  ? SER G 255 GLN G 268 1 ? 14 
HELX_P HELX_P60 AG6 THR G 69  ? PHE G 76  ? THR G 276 PHE G 283 1 ? 8  
HELX_P HELX_P61 AG7 THR G 80  ? MET G 85  ? THR G 287 MET G 292 5 ? 6  
HELX_P HELX_P62 AG8 VAL G 89  ? MET G 104 ? VAL G 296 MET G 311 1 ? 16 
HELX_P HELX_P63 AG9 GLY G 111 ? ARG G 118 ? GLY G 318 ARG G 325 1 ? 8  
HELX_P HELX_P64 AH1 ASN G 152 ? VAL G 161 ? ASN G 359 VAL G 368 1 ? 10 
HELX_P HELX_P65 AH2 ASP G 167 ? LYS G 171 ? ASP G 374 LYS G 378 5 ? 5  
HELX_P HELX_P66 AH3 GLY G 175 ? HIS G 177 ? GLY G 382 HIS G 384 5 ? 3  
HELX_P HELX_P67 AH4 ASP G 227 ? LEU G 230 ? ASP G 434 LEU G 437 5 ? 4  
HELX_P HELX_P68 AH5 THR G 282 ? ILE G 287 ? THR G 489 ILE G 494 1 ? 6  
HELX_P HELX_P69 AH6 GLU G 288 ? TYR G 291 ? GLU G 495 TYR G 498 5 ? 4  
HELX_P HELX_P70 AH7 LYS G 316 ? LEU G 321 ? LYS G 523 LEU G 528 1 ? 6  
HELX_P HELX_P71 AH8 THR H 22  ? GLY H 35  ? THR H 22  GLY H 35  1 ? 14 
HELX_P HELX_P72 AH9 LEU H 56  ? ASN H 60  ? LEU H 56  ASN H 60  5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 5 ? 
AA3 ? 7 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 5 ? 
AA7 ? 4 ? 
AA8 ? 5 ? 
AA9 ? 7 ? 
AB1 ? 2 ? 
AB2 ? 2 ? 
AB3 ? 5 ? 
AB4 ? 4 ? 
AB5 ? 5 ? 
AB6 ? 7 ? 
AB7 ? 2 ? 
AB8 ? 2 ? 
AB9 ? 5 ? 
AC1 ? 2 ? 
AC2 ? 2 ? 
AC3 ? 4 ? 
AC4 ? 5 ? 
AC5 ? 7 ? 
AC6 ? 2 ? 
AC7 ? 2 ? 
AC8 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AA9 6 7 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? parallel      
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB6 4 5 ? anti-parallel 
AB6 5 6 ? anti-parallel 
AB6 6 7 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? parallel      
AB9 3 4 ? anti-parallel 
AB9 4 5 ? anti-parallel 
AC1 1 2 ? parallel      
AC2 1 2 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? parallel      
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
AC4 4 5 ? anti-parallel 
AC5 1 2 ? parallel      
AC5 2 3 ? anti-parallel 
AC5 3 4 ? anti-parallel 
AC5 4 5 ? anti-parallel 
AC5 5 6 ? anti-parallel 
AC5 6 7 ? anti-parallel 
AC6 1 2 ? anti-parallel 
AC7 1 2 ? anti-parallel 
AC8 1 2 ? anti-parallel 
AC8 2 3 ? parallel      
AC8 3 4 ? anti-parallel 
AC8 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 133 ? TYR A 140 ? ARG A 340 TYR A 347 
AA1 2 GLY A 119 ? CYS A 127 ? GLY A 326 CYS A 334 
AA1 3 ALA A 182 ? PHE A 188 ? ALA A 389 PHE A 395 
AA1 4 GLU A 164 ? LEU A 166 ? GLU A 371 LEU A 373 
AA2 1 ILE A 143 ? LEU A 145 ? ILE A 350 LEU A 352 
AA2 2 VAL A 194 ? LEU A 199 ? VAL A 401 LEU A 406 
AA2 3 THR A 304 ? ARG A 313 ? THR A 511 ARG A 520 
AA2 4 ASN A 240 ? GLY A 251 ? ASN A 447 GLY A 458 
AA2 5 GLN A 223 ? PRO A 225 ? GLN A 430 PRO A 432 
AA3 1 ILE A 143 ? LEU A 145 ? ILE A 350 LEU A 352 
AA3 2 VAL A 194 ? LEU A 199 ? VAL A 401 LEU A 406 
AA3 3 THR A 304 ? ARG A 313 ? THR A 511 ARG A 520 
AA3 4 ASN A 240 ? GLY A 251 ? ASN A 447 GLY A 458 
AA3 5 GLY A 256 ? LEU A 262 ? GLY A 463 LEU A 469 
AA3 6 TRP A 270 ? ASP A 274 ? TRP A 477 ASP A 481 
AA3 7 VAL A 277 ? CYS A 281 ? VAL A 484 CYS A 488 
AA4 1 TYR A 172 ? ASP A 173 ? TYR A 379 ASP A 380 
AA4 2 LEU A 179 ? GLN A 180 ? LEU A 386 GLN A 387 
AA5 1 PHE A 202 ? MET A 203 ? PHE A 409 MET A 410 
AA5 2 ILE A 212 ? LYS A 213 ? ILE A 419 LYS A 420 
AA6 1 THR B 12  ? GLU B 16  ? THR B 12  GLU B 16  
AA6 2 GLN B 2   ? LYS B 6   ? GLN B 2   LYS B 6   
AA6 3 THR B 66  ? VAL B 70  ? THR B 66  VAL B 70  
AA6 4 ARG B 42  ? PHE B 45  ? ARG B 42  PHE B 45  
AA6 5 LYS B 48  ? GLN B 49  ? LYS B 48  GLN B 49  
AA7 1 ARG C 133 ? TYR C 140 ? ARG C 340 TYR C 347 
AA7 2 GLY C 119 ? CYS C 127 ? GLY C 326 CYS C 334 
AA7 3 ALA C 182 ? THR C 190 ? ALA C 389 THR C 397 
AA7 4 GLU C 164 ? LEU C 166 ? GLU C 371 LEU C 373 
AA8 1 ILE C 143 ? SER C 146 ? ILE C 350 SER C 353 
AA8 2 VAL C 194 ? MET C 200 ? VAL C 401 MET C 407 
AA8 3 THR C 304 ? ARG C 313 ? THR C 511 ARG C 520 
AA8 4 ASN C 240 ? GLY C 251 ? ASN C 447 GLY C 458 
AA8 5 GLN C 223 ? PRO C 225 ? GLN C 430 PRO C 432 
AA9 1 ILE C 143 ? SER C 146 ? ILE C 350 SER C 353 
AA9 2 VAL C 194 ? MET C 200 ? VAL C 401 MET C 407 
AA9 3 THR C 304 ? ARG C 313 ? THR C 511 ARG C 520 
AA9 4 ASN C 240 ? GLY C 251 ? ASN C 447 GLY C 458 
AA9 5 GLY C 256 ? LEU C 262 ? GLY C 463 LEU C 469 
AA9 6 CYS C 271 ? ASP C 274 ? CYS C 478 ASP C 481 
AA9 7 VAL C 277 ? ARG C 280 ? VAL C 484 ARG C 487 
AB1 1 TYR C 172 ? ASP C 173 ? TYR C 379 ASP C 380 
AB1 2 LEU C 179 ? GLN C 180 ? LEU C 386 GLN C 387 
AB2 1 PHE C 202 ? MET C 203 ? PHE C 409 MET C 410 
AB2 2 ILE C 212 ? LYS C 213 ? ILE C 419 LYS C 420 
AB3 1 THR D 12  ? GLU D 16  ? THR D 12  GLU D 16  
AB3 2 GLN D 2   ? LYS D 6   ? GLN D 2   LYS D 6   
AB3 3 THR D 66  ? VAL D 70  ? THR D 66  VAL D 70  
AB3 4 ARG D 42  ? PHE D 45  ? ARG D 42  PHE D 45  
AB3 5 LYS D 48  ? GLN D 49  ? LYS D 48  GLN D 49  
AB4 1 ARG E 133 ? TYR E 140 ? ARG E 340 TYR E 347 
AB4 2 GLY E 119 ? CYS E 127 ? GLY E 326 CYS E 334 
AB4 3 ALA E 182 ? THR E 190 ? ALA E 389 THR E 397 
AB4 4 GLU E 164 ? LEU E 166 ? GLU E 371 LEU E 373 
AB5 1 ILE E 143 ? SER E 146 ? ILE E 350 SER E 353 
AB5 2 VAL E 194 ? MET E 200 ? VAL E 401 MET E 407 
AB5 3 THR E 304 ? ARG E 313 ? THR E 511 ARG E 520 
AB5 4 ASN E 240 ? GLY E 251 ? ASN E 447 GLY E 458 
AB5 5 GLN E 223 ? PRO E 225 ? GLN E 430 PRO E 432 
AB6 1 ILE E 143 ? SER E 146 ? ILE E 350 SER E 353 
AB6 2 VAL E 194 ? MET E 200 ? VAL E 401 MET E 407 
AB6 3 THR E 304 ? ARG E 313 ? THR E 511 ARG E 520 
AB6 4 ASN E 240 ? GLY E 251 ? ASN E 447 GLY E 458 
AB6 5 GLY E 256 ? LEU E 262 ? GLY E 463 LEU E 469 
AB6 6 CYS E 271 ? ASP E 274 ? CYS E 478 ASP E 481 
AB6 7 VAL E 277 ? ARG E 280 ? VAL E 484 ARG E 487 
AB7 1 TYR E 172 ? ASP E 173 ? TYR E 379 ASP E 380 
AB7 2 LEU E 179 ? GLN E 180 ? LEU E 386 GLN E 387 
AB8 1 PHE E 202 ? MET E 203 ? PHE E 409 MET E 410 
AB8 2 ILE E 212 ? LYS E 213 ? ILE E 419 LYS E 420 
AB9 1 THR F 12  ? GLU F 16  ? THR F 12  GLU F 16  
AB9 2 GLN F 2   ? LYS F 6   ? GLN F 2   LYS F 6   
AB9 3 THR F 66  ? VAL F 70  ? THR F 66  VAL F 70  
AB9 4 ARG F 42  ? PHE F 45  ? ARG F 42  PHE F 45  
AB9 5 LYS F 48  ? GLN F 49  ? LYS F 48  GLN F 49  
AC1 1 LEU G 9   ? LYS G 10  ? LEU G 216 LYS G 217 
AC1 2 VAL G 67  ? GLY G 68  ? VAL G 274 GLY G 275 
AC2 1 HIS G 87  ? ASP G 88  ? HIS G 294 ASP G 295 
AC2 2 ARG H 74  ? GLY H 75  ? ARG H 74  GLY H 75  
AC3 1 ARG G 133 ? TYR G 140 ? ARG G 340 TYR G 347 
AC3 2 GLY G 119 ? CYS G 127 ? GLY G 326 CYS G 334 
AC3 3 ALA G 182 ? THR G 190 ? ALA G 389 THR G 397 
AC3 4 GLU G 164 ? LEU G 166 ? GLU G 371 LEU G 373 
AC4 1 ILE G 143 ? SER G 146 ? ILE G 350 SER G 353 
AC4 2 VAL G 194 ? MET G 200 ? VAL G 401 MET G 407 
AC4 3 THR G 304 ? ARG G 313 ? THR G 511 ARG G 520 
AC4 4 ASN G 240 ? GLY G 251 ? ASN G 447 GLY G 458 
AC4 5 GLN G 223 ? PRO G 225 ? GLN G 430 PRO G 432 
AC5 1 ILE G 143 ? SER G 146 ? ILE G 350 SER G 353 
AC5 2 VAL G 194 ? MET G 200 ? VAL G 401 MET G 407 
AC5 3 THR G 304 ? ARG G 313 ? THR G 511 ARG G 520 
AC5 4 ASN G 240 ? GLY G 251 ? ASN G 447 GLY G 458 
AC5 5 GLY G 256 ? LEU G 262 ? GLY G 463 LEU G 469 
AC5 6 CYS G 271 ? ASP G 274 ? CYS G 478 ASP G 481 
AC5 7 VAL G 277 ? VAL G 278 ? VAL G 484 VAL G 485 
AC6 1 TYR G 172 ? ASP G 173 ? TYR G 379 ASP G 380 
AC6 2 LEU G 179 ? GLN G 180 ? LEU G 386 GLN G 387 
AC7 1 PHE G 202 ? MET G 203 ? PHE G 409 MET G 410 
AC7 2 ILE G 212 ? LYS G 213 ? ILE G 419 LYS G 420 
AC8 1 THR H 12  ? GLU H 16  ? THR H 12  GLU H 16  
AC8 2 GLN H 2   ? LYS H 6   ? GLN H 2   LYS H 6   
AC8 3 THR H 66  ? VAL H 70  ? THR H 66  VAL H 70  
AC8 4 ARG H 42  ? PHE H 45  ? ARG H 42  PHE H 45  
AC8 5 LYS H 48  ? GLN H 49  ? LYS H 48  GLN H 49  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLU A 138 ? O GLU A 345 N MET A 121 ? N MET A 328 
AA1 2 3 N VAL A 122 ? N VAL A 329 O LYS A 187 ? O LYS A 394 
AA1 3 4 O ALA A 182 ? O ALA A 389 N LEU A 166 ? N LEU A 373 
AA2 1 2 N ILE A 143 ? N ILE A 350 O GLN A 198 ? O GLN A 405 
AA2 2 3 N LEU A 195 ? N LEU A 402 O TYR A 311 ? O TYR A 518 
AA2 3 4 O ILE A 312 ? O ILE A 519 N ILE A 242 ? N ILE A 449 
AA2 4 5 O TYR A 241 ? O TYR A 448 N LEU A 224 ? N LEU A 431 
AA3 1 2 N ILE A 143 ? N ILE A 350 O GLN A 198 ? O GLN A 405 
AA3 2 3 N LEU A 195 ? N LEU A 402 O TYR A 311 ? O TYR A 518 
AA3 3 4 O ILE A 312 ? O ILE A 519 N ILE A 242 ? N ILE A 449 
AA3 4 5 N VAL A 246 ? N VAL A 453 O TYR A 261 ? O TYR A 468 
AA3 5 6 N LEU A 262 ? N LEU A 469 O CYS A 271 ? O CYS A 478 
AA3 6 7 N ASP A 274 ? N ASP A 481 O VAL A 277 ? O VAL A 484 
AA4 1 2 N TYR A 172 ? N TYR A 379 O GLN A 180 ? O GLN A 387 
AA5 1 2 N MET A 203 ? N MET A 410 O ILE A 212 ? O ILE A 419 
AA6 1 2 O ILE B 13  ? O ILE B 13  N VAL B 5   ? N VAL B 5   
AA6 2 3 N LYS B 6   ? N LYS B 6   O LEU B 67  ? O LEU B 67  
AA6 3 4 O HIS B 68  ? O HIS B 68  N ILE B 44  ? N ILE B 44  
AA6 4 5 N PHE B 45  ? N PHE B 45  O LYS B 48  ? O LYS B 48  
AA7 1 2 O SER C 134 ? O SER C 341 N ILE C 125 ? N ILE C 332 
AA7 2 3 N LYS C 120 ? N LYS C 327 O LEU C 189 ? O LEU C 396 
AA7 3 4 O LYS C 184 ? O LYS C 391 N GLU C 164 ? N GLU C 371 
AA8 1 2 N ILE C 143 ? N ILE C 350 O GLN C 198 ? O GLN C 405 
AA8 2 3 N LEU C 195 ? N LEU C 402 O TYR C 311 ? O TYR C 518 
AA8 3 4 O ILE C 312 ? O ILE C 519 N ILE C 242 ? N ILE C 449 
AA8 4 5 O TYR C 241 ? O TYR C 448 N LEU C 224 ? N LEU C 431 
AA9 1 2 N ILE C 143 ? N ILE C 350 O GLN C 198 ? O GLN C 405 
AA9 2 3 N LEU C 195 ? N LEU C 402 O TYR C 311 ? O TYR C 518 
AA9 3 4 O ILE C 312 ? O ILE C 519 N ILE C 242 ? N ILE C 449 
AA9 4 5 N VAL C 248 ? N VAL C 455 O VAL C 259 ? O VAL C 466 
AA9 5 6 N VAL C 260 ? N VAL C 467 O PHE C 273 ? O PHE C 480 
AA9 6 7 N LYS C 272 ? N LYS C 479 O SER C 279 ? O SER C 486 
AB1 1 2 N TYR C 172 ? N TYR C 379 O GLN C 180 ? O GLN C 387 
AB2 1 2 N MET C 203 ? N MET C 410 O ILE C 212 ? O ILE C 419 
AB3 1 2 O LEU D 15  ? O LEU D 15  N ILE D 3   ? N ILE D 3   
AB3 2 3 N LYS D 6   ? N LYS D 6   O LEU D 67  ? O LEU D 67  
AB3 3 4 O HIS D 68  ? O HIS D 68  N ILE D 44  ? N ILE D 44  
AB3 4 5 N PHE D 45  ? N PHE D 45  O LYS D 48  ? O LYS D 48  
AB4 1 2 O SER E 134 ? O SER E 341 N ILE E 125 ? N ILE E 332 
AB4 2 3 N VAL E 122 ? N VAL E 329 O LYS E 187 ? O LYS E 394 
AB4 3 4 O ALA E 182 ? O ALA E 389 N LEU E 166 ? N LEU E 373 
AB5 1 2 N ILE E 143 ? N ILE E 350 O GLN E 198 ? O GLN E 405 
AB5 2 3 N LEU E 195 ? N LEU E 402 O TYR E 311 ? O TYR E 518 
AB5 3 4 O ILE E 312 ? O ILE E 519 N ILE E 242 ? N ILE E 449 
AB5 4 5 O TYR E 241 ? O TYR E 448 N LEU E 224 ? N LEU E 431 
AB6 1 2 N ILE E 143 ? N ILE E 350 O GLN E 198 ? O GLN E 405 
AB6 2 3 N LEU E 195 ? N LEU E 402 O TYR E 311 ? O TYR E 518 
AB6 3 4 O ILE E 312 ? O ILE E 519 N ILE E 242 ? N ILE E 449 
AB6 4 5 N VAL E 248 ? N VAL E 455 O VAL E 259 ? O VAL E 466 
AB6 5 6 N VAL E 260 ? N VAL E 467 O PHE E 273 ? O PHE E 480 
AB6 6 7 N LYS E 272 ? N LYS E 479 O SER E 279 ? O SER E 486 
AB7 1 2 N TYR E 172 ? N TYR E 379 O GLN E 180 ? O GLN E 387 
AB8 1 2 N MET E 203 ? N MET E 410 O ILE E 212 ? O ILE E 419 
AB9 1 2 O ILE F 13  ? O ILE F 13  N VAL F 5   ? N VAL F 5   
AB9 2 3 N LYS F 6   ? N LYS F 6   O LEU F 67  ? O LEU F 67  
AB9 3 4 O HIS F 68  ? O HIS F 68  N ILE F 44  ? N ILE F 44  
AB9 4 5 N PHE F 45  ? N PHE F 45  O LYS F 48  ? O LYS F 48  
AC1 1 2 N LYS G 10  ? N LYS G 217 O VAL G 67  ? O VAL G 274 
AC2 1 2 N HIS G 87  ? N HIS G 294 O GLY H 75  ? O GLY H 75  
AC3 1 2 O GLU G 138 ? O GLU G 345 N MET G 121 ? N MET G 328 
AC3 2 3 N GLN G 126 ? N GLN G 333 O GLU G 183 ? O GLU G 390 
AC3 3 4 O ALA G 182 ? O ALA G 389 N LEU G 166 ? N LEU G 373 
AC4 1 2 N ILE G 143 ? N ILE G 350 O GLN G 198 ? O GLN G 405 
AC4 2 3 N LEU G 195 ? N LEU G 402 O TYR G 311 ? O TYR G 518 
AC4 3 4 O MET G 308 ? O MET G 515 N LEU G 247 ? N LEU G 454 
AC4 4 5 O TYR G 241 ? O TYR G 448 N LEU G 224 ? N LEU G 431 
AC5 1 2 N ILE G 143 ? N ILE G 350 O GLN G 198 ? O GLN G 405 
AC5 2 3 N LEU G 195 ? N LEU G 402 O TYR G 311 ? O TYR G 518 
AC5 3 4 O MET G 308 ? O MET G 515 N LEU G 247 ? N LEU G 454 
AC5 4 5 N VAL G 248 ? N VAL G 455 O VAL G 259 ? O VAL G 466 
AC5 5 6 N LEU G 262 ? N LEU G 469 O CYS G 271 ? O CYS G 478 
AC5 6 7 N ASP G 274 ? N ASP G 481 O VAL G 277 ? O VAL G 484 
AC6 1 2 N TYR G 172 ? N TYR G 379 O GLN G 180 ? O GLN G 387 
AC7 1 2 N MET G 203 ? N MET G 410 O ILE G 212 ? O ILE G 419 
AC8 1 2 O ILE H 13  ? O ILE H 13  N VAL H 5   ? N VAL H 5   
AC8 2 3 N LYS H 6   ? N LYS H 6   O LEU H 67  ? O LEU H 67  
AC8 3 4 O HIS H 68  ? O HIS H 68  N ILE H 44  ? N ILE H 44  
AC8 4 5 N PHE H 45  ? N PHE H 45  O LYS H 48  ? O LYS H 48  
# 
_pdbx_entry_details.entry_id                   9IJU 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 246 ? ? -68.37  96.06   
2  1 SER A 253 ? ? 47.37   25.79   
3  1 ALA A 381 ? ? -90.21  39.94   
4  1 ASP A 482 ? ? 58.38   -112.32 
5  1 ILE A 494 ? ? -109.35 -76.92  
6  1 THR A 532 ? ? -127.81 -166.72 
7  1 GLU A 547 ? ? -151.97 79.90   
8  1 GLN B 62  ? ? -120.02 -160.08 
9  1 LEU B 71  ? ? -103.54 -157.62 
10 1 ALA C 221 ? ? -144.59 18.26   
11 1 ALA C 381 ? ? -95.38  39.63   
12 1 ARG C 408 ? ? -92.72  53.22   
13 1 ASP C 444 ? ? -153.95 71.45   
14 1 ASP C 459 ? ? -114.79 -169.52 
15 1 ASP C 482 ? ? 53.09   -108.50 
16 1 ILE C 494 ? ? -105.15 -81.39  
17 1 ARG C 549 ? ? -61.28  89.04   
18 1 GLU D 64  ? ? 82.54   -3.91   
19 1 LEU D 71  ? ? -104.79 -147.31 
20 1 ALA E 221 ? ? -144.70 27.37   
21 1 PRO E 273 ? ? -30.56  128.42  
22 1 ALA E 381 ? ? -100.29 49.42   
23 1 ASP E 444 ? ? -164.81 84.55   
24 1 ASP E 482 ? ? 53.29   -116.13 
25 1 ILE E 494 ? ? -110.01 -78.12  
26 1 LEU F 71  ? ? -107.07 -146.52 
27 1 ALA G 221 ? ? -141.05 18.79   
28 1 THR G 222 ? ? -86.25  30.57   
29 1 PRO G 246 ? ? -60.52  95.05   
30 1 THR G 247 ? ? -92.02  -125.54 
31 1 PRO G 273 ? ? -45.93  151.67  
32 1 ALA G 381 ? ? -109.29 42.70   
33 1 ARG G 408 ? ? -93.62  52.11   
34 1 ASP G 444 ? ? -174.61 91.29   
35 1 ASP G 482 ? ? 54.58   -96.95  
36 1 ILE G 494 ? ? -117.90 -70.96  
37 1 ASN G 512 ? ? 176.50  170.89  
38 1 LEU G 528 ? ? -92.22  47.66   
39 1 GLN G 529 ? ? -78.21  -160.91 
40 1 GLU H 64  ? ? 64.64   -1.51   
41 1 LEU H 71  ? ? -104.67 -154.83 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A LYS 208 ? A LYS 1   
2   1 Y 1 A LYS 209 ? A LYS 2   
3   1 Y 1 A GLY 249 ? A GLY 42  
4   1 Y 1 A ASP 412 ? A ASP 205 
5   1 Y 1 A PRO 413 ? A PRO 206 
6   1 Y 1 A GLN 414 ? A GLN 207 
7   1 Y 1 A HIS 501 ? A HIS 294 
8   1 Y 1 A ASP 502 ? A ASP 295 
9   1 Y 1 A ASP 503 ? A ASP 296 
10  1 Y 1 A ASP 504 ? A ASP 297 
11  1 Y 1 A LEU 505 ? A LEU 298 
12  1 Y 1 A SER 506 ? A SER 299 
13  1 Y 1 A VAL 507 ? A VAL 300 
14  1 Y 1 A ARG 508 ? A ARG 301 
15  1 Y 1 A HIS 509 ? A HIS 302 
16  1 Y 1 A ARG 549 ? A ARG 342 
17  1 Y 1 A ILE 550 ? A ILE 343 
18  1 Y 1 A GLU 551 ? A GLU 344 
19  1 Y 1 A ALA 552 ? A ALA 345 
20  1 Y 1 A GLN 553 ? A GLN 346 
21  1 Y 1 A LYS 554 ? A LYS 347 
22  1 Y 1 A ARG 555 ? A ARG 348 
23  1 Y 1 A LYS 556 ? A LYS 349 
24  1 Y 1 A GLU 557 ? A GLU 350 
25  1 Y 1 A ARG 558 ? A ARG 351 
26  1 Y 1 A GLN 559 ? A GLN 352 
27  1 Y 1 A GLU 560 ? A GLU 353 
28  1 Y 1 C LYS 208 ? C LYS 1   
29  1 Y 1 C LYS 209 ? C LYS 2   
30  1 Y 1 C HIS 210 ? C HIS 3   
31  1 Y 1 C GLU 248 ? C GLU 41  
32  1 Y 1 C GLY 249 ? C GLY 42  
33  1 Y 1 C ASP 250 ? C ASP 43  
34  1 Y 1 C ASP 251 ? C ASP 44  
35  1 Y 1 C SER 252 ? C SER 45  
36  1 Y 1 C ASP 412 ? C ASP 205 
37  1 Y 1 C PRO 413 ? C PRO 206 
38  1 Y 1 C GLN 414 ? C GLN 207 
39  1 Y 1 C HIS 501 ? C HIS 294 
40  1 Y 1 C ASP 502 ? C ASP 295 
41  1 Y 1 C ASP 503 ? C ASP 296 
42  1 Y 1 C ASP 504 ? C ASP 297 
43  1 Y 1 C LEU 505 ? C LEU 298 
44  1 Y 1 C SER 506 ? C SER 299 
45  1 Y 1 C VAL 507 ? C VAL 300 
46  1 Y 1 C ARG 508 ? C ARG 301 
47  1 Y 1 C HIS 509 ? C HIS 302 
48  1 Y 1 C GLN 553 ? C GLN 346 
49  1 Y 1 C LYS 554 ? C LYS 347 
50  1 Y 1 C ARG 555 ? C ARG 348 
51  1 Y 1 C LYS 556 ? C LYS 349 
52  1 Y 1 C GLU 557 ? C GLU 350 
53  1 Y 1 C ARG 558 ? C ARG 351 
54  1 Y 1 C GLN 559 ? C GLN 352 
55  1 Y 1 C GLU 560 ? C GLU 353 
56  1 Y 1 E LYS 208 ? E LYS 1   
57  1 Y 1 E LYS 209 ? E LYS 2   
58  1 Y 1 E HIS 210 ? E HIS 3   
59  1 Y 1 E ASP 251 ? E ASP 44  
60  1 Y 1 E TYR 411 ? E TYR 204 
61  1 Y 1 E ASP 412 ? E ASP 205 
62  1 Y 1 E PRO 413 ? E PRO 206 
63  1 Y 1 E GLN 414 ? E GLN 207 
64  1 Y 1 E THR 415 ? E THR 208 
65  1 Y 1 E ASP 416 ? E ASP 209 
66  1 Y 1 E HIS 501 ? E HIS 294 
67  1 Y 1 E ASP 502 ? E ASP 295 
68  1 Y 1 E ASP 503 ? E ASP 296 
69  1 Y 1 E ASP 504 ? E ASP 297 
70  1 Y 1 E LEU 505 ? E LEU 298 
71  1 Y 1 E SER 506 ? E SER 299 
72  1 Y 1 E VAL 507 ? E VAL 300 
73  1 Y 1 E LYS 548 ? E LYS 341 
74  1 Y 1 E ARG 549 ? E ARG 342 
75  1 Y 1 E ILE 550 ? E ILE 343 
76  1 Y 1 E GLU 551 ? E GLU 344 
77  1 Y 1 E ALA 552 ? E ALA 345 
78  1 Y 1 E GLN 553 ? E GLN 346 
79  1 Y 1 E LYS 554 ? E LYS 347 
80  1 Y 1 E ARG 555 ? E ARG 348 
81  1 Y 1 E LYS 556 ? E LYS 349 
82  1 Y 1 E GLU 557 ? E GLU 350 
83  1 Y 1 E ARG 558 ? E ARG 351 
84  1 Y 1 E GLN 559 ? E GLN 352 
85  1 Y 1 E GLU 560 ? E GLU 353 
86  1 Y 1 G LYS 208 ? G LYS 1   
87  1 Y 1 G LYS 209 ? G LYS 2   
88  1 Y 1 G HIS 210 ? G HIS 3   
89  1 Y 1 G THR 211 ? G THR 4   
90  1 Y 1 G GLY 212 ? G GLY 5   
91  1 Y 1 G TYR 213 ? G TYR 6   
92  1 Y 1 G GLY 249 ? G GLY 42  
93  1 Y 1 G ASP 250 ? G ASP 43  
94  1 Y 1 G ASP 251 ? G ASP 44  
95  1 Y 1 G SER 252 ? G SER 45  
96  1 Y 1 G HIS 269 ? G HIS 62  
97  1 Y 1 G SER 270 ? G SER 63  
98  1 Y 1 G GLN 414 ? G GLN 207 
99  1 Y 1 G THR 415 ? G THR 208 
100 1 Y 1 G ASP 416 ? G ASP 209 
101 1 Y 1 G GLN 417 ? G GLN 210 
102 1 Y 1 G GLY 499 ? G GLY 292 
103 1 Y 1 G GLY 500 ? G GLY 293 
104 1 Y 1 G HIS 501 ? G HIS 294 
105 1 Y 1 G ASP 502 ? G ASP 295 
106 1 Y 1 G ASP 503 ? G ASP 296 
107 1 Y 1 G ASP 504 ? G ASP 297 
108 1 Y 1 G LEU 505 ? G LEU 298 
109 1 Y 1 G SER 506 ? G SER 299 
110 1 Y 1 G VAL 507 ? G VAL 300 
111 1 Y 1 G VAL 531 ? G VAL 324 
112 1 Y 1 G THR 532 ? G THR 325 
113 1 Y 1 G ASP 533 ? G ASP 326 
114 1 Y 1 G HIS 534 ? G HIS 327 
115 1 Y 1 G ASP 535 ? G ASP 328 
116 1 Y 1 G ILE 536 ? G ILE 329 
117 1 Y 1 G PRO 537 ? G PRO 330 
118 1 Y 1 G GLN 538 ? G GLN 331 
119 1 Y 1 G GLN 539 ? G GLN 332 
120 1 Y 1 G LEU 540 ? G LEU 333 
121 1 Y 1 G VAL 541 ? G VAL 334 
122 1 Y 1 G GLU 542 ? G GLU 335 
123 1 Y 1 G ARG 543 ? G ARG 336 
124 1 Y 1 G LEU 544 ? G LEU 337 
125 1 Y 1 G GLN 545 ? G GLN 338 
126 1 Y 1 G GLU 546 ? G GLU 339 
127 1 Y 1 G GLU 547 ? G GLU 340 
128 1 Y 1 G LYS 548 ? G LYS 341 
129 1 Y 1 G ARG 549 ? G ARG 342 
130 1 Y 1 G ILE 550 ? G ILE 343 
131 1 Y 1 G GLU 551 ? G GLU 344 
132 1 Y 1 G ALA 552 ? G ALA 345 
133 1 Y 1 G GLN 553 ? G GLN 346 
134 1 Y 1 G LYS 554 ? G LYS 347 
135 1 Y 1 G ARG 555 ? G ARG 348 
136 1 Y 1 G LYS 556 ? G LYS 349 
137 1 Y 1 G GLU 557 ? G GLU 350 
138 1 Y 1 G ARG 558 ? G ARG 351 
139 1 Y 1 G GLN 559 ? G GLN 352 
140 1 Y 1 G GLU 560 ? G GLU 353 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
HOH O    O  N N 158 
HOH H1   H  N N 159 
HOH H2   H  N N 160 
ILE N    N  N N 161 
ILE CA   C  N S 162 
ILE C    C  N N 163 
ILE O    O  N N 164 
ILE CB   C  N S 165 
ILE CG1  C  N N 166 
ILE CG2  C  N N 167 
ILE CD1  C  N N 168 
ILE OXT  O  N N 169 
ILE H    H  N N 170 
ILE H2   H  N N 171 
ILE HA   H  N N 172 
ILE HB   H  N N 173 
ILE HG12 H  N N 174 
ILE HG13 H  N N 175 
ILE HG21 H  N N 176 
ILE HG22 H  N N 177 
ILE HG23 H  N N 178 
ILE HD11 H  N N 179 
ILE HD12 H  N N 180 
ILE HD13 H  N N 181 
ILE HXT  H  N N 182 
LEU N    N  N N 183 
LEU CA   C  N S 184 
LEU C    C  N N 185 
LEU O    O  N N 186 
LEU CB   C  N N 187 
LEU CG   C  N N 188 
LEU CD1  C  N N 189 
LEU CD2  C  N N 190 
LEU OXT  O  N N 191 
LEU H    H  N N 192 
LEU H2   H  N N 193 
LEU HA   H  N N 194 
LEU HB2  H  N N 195 
LEU HB3  H  N N 196 
LEU HG   H  N N 197 
LEU HD11 H  N N 198 
LEU HD12 H  N N 199 
LEU HD13 H  N N 200 
LEU HD21 H  N N 201 
LEU HD22 H  N N 202 
LEU HD23 H  N N 203 
LEU HXT  H  N N 204 
LYS N    N  N N 205 
LYS CA   C  N S 206 
LYS C    C  N N 207 
LYS O    O  N N 208 
LYS CB   C  N N 209 
LYS CG   C  N N 210 
LYS CD   C  N N 211 
LYS CE   C  N N 212 
LYS NZ   N  N N 213 
LYS OXT  O  N N 214 
LYS H    H  N N 215 
LYS H2   H  N N 216 
LYS HA   H  N N 217 
LYS HB2  H  N N 218 
LYS HB3  H  N N 219 
LYS HG2  H  N N 220 
LYS HG3  H  N N 221 
LYS HD2  H  N N 222 
LYS HD3  H  N N 223 
LYS HE2  H  N N 224 
LYS HE3  H  N N 225 
LYS HZ1  H  N N 226 
LYS HZ2  H  N N 227 
LYS HZ3  H  N N 228 
LYS HXT  H  N N 229 
MET N    N  N N 230 
MET CA   C  N S 231 
MET C    C  N N 232 
MET O    O  N N 233 
MET CB   C  N N 234 
MET CG   C  N N 235 
MET SD   S  N N 236 
MET CE   C  N N 237 
MET OXT  O  N N 238 
MET H    H  N N 239 
MET H2   H  N N 240 
MET HA   H  N N 241 
MET HB2  H  N N 242 
MET HB3  H  N N 243 
MET HG2  H  N N 244 
MET HG3  H  N N 245 
MET HE1  H  N N 246 
MET HE2  H  N N 247 
MET HE3  H  N N 248 
MET HXT  H  N N 249 
PHE N    N  N N 250 
PHE CA   C  N S 251 
PHE C    C  N N 252 
PHE O    O  N N 253 
PHE CB   C  N N 254 
PHE CG   C  Y N 255 
PHE CD1  C  Y N 256 
PHE CD2  C  Y N 257 
PHE CE1  C  Y N 258 
PHE CE2  C  Y N 259 
PHE CZ   C  Y N 260 
PHE OXT  O  N N 261 
PHE H    H  N N 262 
PHE H2   H  N N 263 
PHE HA   H  N N 264 
PHE HB2  H  N N 265 
PHE HB3  H  N N 266 
PHE HD1  H  N N 267 
PHE HD2  H  N N 268 
PHE HE1  H  N N 269 
PHE HE2  H  N N 270 
PHE HZ   H  N N 271 
PHE HXT  H  N N 272 
PRO N    N  N N 273 
PRO CA   C  N S 274 
PRO C    C  N N 275 
PRO O    O  N N 276 
PRO CB   C  N N 277 
PRO CG   C  N N 278 
PRO CD   C  N N 279 
PRO OXT  O  N N 280 
PRO H    H  N N 281 
PRO HA   H  N N 282 
PRO HB2  H  N N 283 
PRO HB3  H  N N 284 
PRO HG2  H  N N 285 
PRO HG3  H  N N 286 
PRO HD2  H  N N 287 
PRO HD3  H  N N 288 
PRO HXT  H  N N 289 
SER N    N  N N 290 
SER CA   C  N S 291 
SER C    C  N N 292 
SER O    O  N N 293 
SER CB   C  N N 294 
SER OG   O  N N 295 
SER OXT  O  N N 296 
SER H    H  N N 297 
SER H2   H  N N 298 
SER HA   H  N N 299 
SER HB2  H  N N 300 
SER HB3  H  N N 301 
SER HG   H  N N 302 
SER HXT  H  N N 303 
SRE CL19 CL N N 304 
SRE C16  C  Y N 305 
SRE C15  C  Y N 306 
SRE CL20 CL N N 307 
SRE C17  C  Y N 308 
SRE C18  C  Y N 309 
SRE C13  C  Y N 310 
SRE C14  C  Y N 311 
SRE C4   C  N S 312 
SRE C5   C  Y N 313 
SRE C6   C  Y N 314 
SRE C7   C  Y N 315 
SRE C8   C  Y N 316 
SRE C9   C  Y N 317 
SRE C10  C  Y N 318 
SRE C1   C  N S 319 
SRE N11  N  N N 320 
SRE C12  C  N N 321 
SRE C2   C  N N 322 
SRE C3   C  N N 323 
SRE H17  H  N N 324 
SRE H18  H  N N 325 
SRE H14  H  N N 326 
SRE H4   H  N N 327 
SRE H6   H  N N 328 
SRE H7   H  N N 329 
SRE H8   H  N N 330 
SRE H9   H  N N 331 
SRE H1   H  N N 332 
SRE H12  H  N N 333 
SRE H12A H  N N 334 
SRE H2   H  N N 335 
SRE H2A  H  N N 336 
SRE H3   H  N N 337 
SRE H3A  H  N N 338 
SRE H16  H  N N 339 
SRE H171 H  N N 340 
THR N    N  N N 341 
THR CA   C  N S 342 
THR C    C  N N 343 
THR O    O  N N 344 
THR CB   C  N R 345 
THR OG1  O  N N 346 
THR CG2  C  N N 347 
THR OXT  O  N N 348 
THR H    H  N N 349 
THR H2   H  N N 350 
THR HA   H  N N 351 
THR HB   H  N N 352 
THR HG1  H  N N 353 
THR HG21 H  N N 354 
THR HG22 H  N N 355 
THR HG23 H  N N 356 
THR HXT  H  N N 357 
TRP N    N  N N 358 
TRP CA   C  N S 359 
TRP C    C  N N 360 
TRP O    O  N N 361 
TRP CB   C  N N 362 
TRP CG   C  Y N 363 
TRP CD1  C  Y N 364 
TRP CD2  C  Y N 365 
TRP NE1  N  Y N 366 
TRP CE2  C  Y N 367 
TRP CE3  C  Y N 368 
TRP CZ2  C  Y N 369 
TRP CZ3  C  Y N 370 
TRP CH2  C  Y N 371 
TRP OXT  O  N N 372 
TRP H    H  N N 373 
TRP H2   H  N N 374 
TRP HA   H  N N 375 
TRP HB2  H  N N 376 
TRP HB3  H  N N 377 
TRP HD1  H  N N 378 
TRP HE1  H  N N 379 
TRP HE3  H  N N 380 
TRP HZ2  H  N N 381 
TRP HZ3  H  N N 382 
TRP HH2  H  N N 383 
TRP HXT  H  N N 384 
TYR N    N  N N 385 
TYR CA   C  N S 386 
TYR C    C  N N 387 
TYR O    O  N N 388 
TYR CB   C  N N 389 
TYR CG   C  Y N 390 
TYR CD1  C  Y N 391 
TYR CD2  C  Y N 392 
TYR CE1  C  Y N 393 
TYR CE2  C  Y N 394 
TYR CZ   C  Y N 395 
TYR OH   O  N N 396 
TYR OXT  O  N N 397 
TYR H    H  N N 398 
TYR H2   H  N N 399 
TYR HA   H  N N 400 
TYR HB2  H  N N 401 
TYR HB3  H  N N 402 
TYR HD1  H  N N 403 
TYR HD2  H  N N 404 
TYR HE1  H  N N 405 
TYR HE2  H  N N 406 
TYR HH   H  N N 407 
TYR HXT  H  N N 408 
VAL N    N  N N 409 
VAL CA   C  N S 410 
VAL C    C  N N 411 
VAL O    O  N N 412 
VAL CB   C  N N 413 
VAL CG1  C  N N 414 
VAL CG2  C  N N 415 
VAL OXT  O  N N 416 
VAL H    H  N N 417 
VAL H2   H  N N 418 
VAL HA   H  N N 419 
VAL HB   H  N N 420 
VAL HG11 H  N N 421 
VAL HG12 H  N N 422 
VAL HG13 H  N N 423 
VAL HG21 H  N N 424 
VAL HG22 H  N N 425 
VAL HG23 H  N N 426 
VAL HXT  H  N N 427 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N    CA   sing N N 1   
ALA N    H    sing N N 2   
ALA N    H2   sing N N 3   
ALA CA   C    sing N N 4   
ALA CA   CB   sing N N 5   
ALA CA   HA   sing N N 6   
ALA C    O    doub N N 7   
ALA C    OXT  sing N N 8   
ALA CB   HB1  sing N N 9   
ALA CB   HB2  sing N N 10  
ALA CB   HB3  sing N N 11  
ALA OXT  HXT  sing N N 12  
ARG N    CA   sing N N 13  
ARG N    H    sing N N 14  
ARG N    H2   sing N N 15  
ARG CA   C    sing N N 16  
ARG CA   CB   sing N N 17  
ARG CA   HA   sing N N 18  
ARG C    O    doub N N 19  
ARG C    OXT  sing N N 20  
ARG CB   CG   sing N N 21  
ARG CB   HB2  sing N N 22  
ARG CB   HB3  sing N N 23  
ARG CG   CD   sing N N 24  
ARG CG   HG2  sing N N 25  
ARG CG   HG3  sing N N 26  
ARG CD   NE   sing N N 27  
ARG CD   HD2  sing N N 28  
ARG CD   HD3  sing N N 29  
ARG NE   CZ   sing N N 30  
ARG NE   HE   sing N N 31  
ARG CZ   NH1  sing N N 32  
ARG CZ   NH2  doub N N 33  
ARG NH1  HH11 sing N N 34  
ARG NH1  HH12 sing N N 35  
ARG NH2  HH21 sing N N 36  
ARG NH2  HH22 sing N N 37  
ARG OXT  HXT  sing N N 38  
ASN N    CA   sing N N 39  
ASN N    H    sing N N 40  
ASN N    H2   sing N N 41  
ASN CA   C    sing N N 42  
ASN CA   CB   sing N N 43  
ASN CA   HA   sing N N 44  
ASN C    O    doub N N 45  
ASN C    OXT  sing N N 46  
ASN CB   CG   sing N N 47  
ASN CB   HB2  sing N N 48  
ASN CB   HB3  sing N N 49  
ASN CG   OD1  doub N N 50  
ASN CG   ND2  sing N N 51  
ASN ND2  HD21 sing N N 52  
ASN ND2  HD22 sing N N 53  
ASN OXT  HXT  sing N N 54  
ASP N    CA   sing N N 55  
ASP N    H    sing N N 56  
ASP N    H2   sing N N 57  
ASP CA   C    sing N N 58  
ASP CA   CB   sing N N 59  
ASP CA   HA   sing N N 60  
ASP C    O    doub N N 61  
ASP C    OXT  sing N N 62  
ASP CB   CG   sing N N 63  
ASP CB   HB2  sing N N 64  
ASP CB   HB3  sing N N 65  
ASP CG   OD1  doub N N 66  
ASP CG   OD2  sing N N 67  
ASP OD2  HD2  sing N N 68  
ASP OXT  HXT  sing N N 69  
CYS N    CA   sing N N 70  
CYS N    H    sing N N 71  
CYS N    H2   sing N N 72  
CYS CA   C    sing N N 73  
CYS CA   CB   sing N N 74  
CYS CA   HA   sing N N 75  
CYS C    O    doub N N 76  
CYS C    OXT  sing N N 77  
CYS CB   SG   sing N N 78  
CYS CB   HB2  sing N N 79  
CYS CB   HB3  sing N N 80  
CYS SG   HG   sing N N 81  
CYS OXT  HXT  sing N N 82  
GLN N    CA   sing N N 83  
GLN N    H    sing N N 84  
GLN N    H2   sing N N 85  
GLN CA   C    sing N N 86  
GLN CA   CB   sing N N 87  
GLN CA   HA   sing N N 88  
GLN C    O    doub N N 89  
GLN C    OXT  sing N N 90  
GLN CB   CG   sing N N 91  
GLN CB   HB2  sing N N 92  
GLN CB   HB3  sing N N 93  
GLN CG   CD   sing N N 94  
GLN CG   HG2  sing N N 95  
GLN CG   HG3  sing N N 96  
GLN CD   OE1  doub N N 97  
GLN CD   NE2  sing N N 98  
GLN NE2  HE21 sing N N 99  
GLN NE2  HE22 sing N N 100 
GLN OXT  HXT  sing N N 101 
GLU N    CA   sing N N 102 
GLU N    H    sing N N 103 
GLU N    H2   sing N N 104 
GLU CA   C    sing N N 105 
GLU CA   CB   sing N N 106 
GLU CA   HA   sing N N 107 
GLU C    O    doub N N 108 
GLU C    OXT  sing N N 109 
GLU CB   CG   sing N N 110 
GLU CB   HB2  sing N N 111 
GLU CB   HB3  sing N N 112 
GLU CG   CD   sing N N 113 
GLU CG   HG2  sing N N 114 
GLU CG   HG3  sing N N 115 
GLU CD   OE1  doub N N 116 
GLU CD   OE2  sing N N 117 
GLU OE2  HE2  sing N N 118 
GLU OXT  HXT  sing N N 119 
GLY N    CA   sing N N 120 
GLY N    H    sing N N 121 
GLY N    H2   sing N N 122 
GLY CA   C    sing N N 123 
GLY CA   HA2  sing N N 124 
GLY CA   HA3  sing N N 125 
GLY C    O    doub N N 126 
GLY C    OXT  sing N N 127 
GLY OXT  HXT  sing N N 128 
HIS N    CA   sing N N 129 
HIS N    H    sing N N 130 
HIS N    H2   sing N N 131 
HIS CA   C    sing N N 132 
HIS CA   CB   sing N N 133 
HIS CA   HA   sing N N 134 
HIS C    O    doub N N 135 
HIS C    OXT  sing N N 136 
HIS CB   CG   sing N N 137 
HIS CB   HB2  sing N N 138 
HIS CB   HB3  sing N N 139 
HIS CG   ND1  sing Y N 140 
HIS CG   CD2  doub Y N 141 
HIS ND1  CE1  doub Y N 142 
HIS ND1  HD1  sing N N 143 
HIS CD2  NE2  sing Y N 144 
HIS CD2  HD2  sing N N 145 
HIS CE1  NE2  sing Y N 146 
HIS CE1  HE1  sing N N 147 
HIS NE2  HE2  sing N N 148 
HIS OXT  HXT  sing N N 149 
HOH O    H1   sing N N 150 
HOH O    H2   sing N N 151 
ILE N    CA   sing N N 152 
ILE N    H    sing N N 153 
ILE N    H2   sing N N 154 
ILE CA   C    sing N N 155 
ILE CA   CB   sing N N 156 
ILE CA   HA   sing N N 157 
ILE C    O    doub N N 158 
ILE C    OXT  sing N N 159 
ILE CB   CG1  sing N N 160 
ILE CB   CG2  sing N N 161 
ILE CB   HB   sing N N 162 
ILE CG1  CD1  sing N N 163 
ILE CG1  HG12 sing N N 164 
ILE CG1  HG13 sing N N 165 
ILE CG2  HG21 sing N N 166 
ILE CG2  HG22 sing N N 167 
ILE CG2  HG23 sing N N 168 
ILE CD1  HD11 sing N N 169 
ILE CD1  HD12 sing N N 170 
ILE CD1  HD13 sing N N 171 
ILE OXT  HXT  sing N N 172 
LEU N    CA   sing N N 173 
LEU N    H    sing N N 174 
LEU N    H2   sing N N 175 
LEU CA   C    sing N N 176 
LEU CA   CB   sing N N 177 
LEU CA   HA   sing N N 178 
LEU C    O    doub N N 179 
LEU C    OXT  sing N N 180 
LEU CB   CG   sing N N 181 
LEU CB   HB2  sing N N 182 
LEU CB   HB3  sing N N 183 
LEU CG   CD1  sing N N 184 
LEU CG   CD2  sing N N 185 
LEU CG   HG   sing N N 186 
LEU CD1  HD11 sing N N 187 
LEU CD1  HD12 sing N N 188 
LEU CD1  HD13 sing N N 189 
LEU CD2  HD21 sing N N 190 
LEU CD2  HD22 sing N N 191 
LEU CD2  HD23 sing N N 192 
LEU OXT  HXT  sing N N 193 
LYS N    CA   sing N N 194 
LYS N    H    sing N N 195 
LYS N    H2   sing N N 196 
LYS CA   C    sing N N 197 
LYS CA   CB   sing N N 198 
LYS CA   HA   sing N N 199 
LYS C    O    doub N N 200 
LYS C    OXT  sing N N 201 
LYS CB   CG   sing N N 202 
LYS CB   HB2  sing N N 203 
LYS CB   HB3  sing N N 204 
LYS CG   CD   sing N N 205 
LYS CG   HG2  sing N N 206 
LYS CG   HG3  sing N N 207 
LYS CD   CE   sing N N 208 
LYS CD   HD2  sing N N 209 
LYS CD   HD3  sing N N 210 
LYS CE   NZ   sing N N 211 
LYS CE   HE2  sing N N 212 
LYS CE   HE3  sing N N 213 
LYS NZ   HZ1  sing N N 214 
LYS NZ   HZ2  sing N N 215 
LYS NZ   HZ3  sing N N 216 
LYS OXT  HXT  sing N N 217 
MET N    CA   sing N N 218 
MET N    H    sing N N 219 
MET N    H2   sing N N 220 
MET CA   C    sing N N 221 
MET CA   CB   sing N N 222 
MET CA   HA   sing N N 223 
MET C    O    doub N N 224 
MET C    OXT  sing N N 225 
MET CB   CG   sing N N 226 
MET CB   HB2  sing N N 227 
MET CB   HB3  sing N N 228 
MET CG   SD   sing N N 229 
MET CG   HG2  sing N N 230 
MET CG   HG3  sing N N 231 
MET SD   CE   sing N N 232 
MET CE   HE1  sing N N 233 
MET CE   HE2  sing N N 234 
MET CE   HE3  sing N N 235 
MET OXT  HXT  sing N N 236 
PHE N    CA   sing N N 237 
PHE N    H    sing N N 238 
PHE N    H2   sing N N 239 
PHE CA   C    sing N N 240 
PHE CA   CB   sing N N 241 
PHE CA   HA   sing N N 242 
PHE C    O    doub N N 243 
PHE C    OXT  sing N N 244 
PHE CB   CG   sing N N 245 
PHE CB   HB2  sing N N 246 
PHE CB   HB3  sing N N 247 
PHE CG   CD1  doub Y N 248 
PHE CG   CD2  sing Y N 249 
PHE CD1  CE1  sing Y N 250 
PHE CD1  HD1  sing N N 251 
PHE CD2  CE2  doub Y N 252 
PHE CD2  HD2  sing N N 253 
PHE CE1  CZ   doub Y N 254 
PHE CE1  HE1  sing N N 255 
PHE CE2  CZ   sing Y N 256 
PHE CE2  HE2  sing N N 257 
PHE CZ   HZ   sing N N 258 
PHE OXT  HXT  sing N N 259 
PRO N    CA   sing N N 260 
PRO N    CD   sing N N 261 
PRO N    H    sing N N 262 
PRO CA   C    sing N N 263 
PRO CA   CB   sing N N 264 
PRO CA   HA   sing N N 265 
PRO C    O    doub N N 266 
PRO C    OXT  sing N N 267 
PRO CB   CG   sing N N 268 
PRO CB   HB2  sing N N 269 
PRO CB   HB3  sing N N 270 
PRO CG   CD   sing N N 271 
PRO CG   HG2  sing N N 272 
PRO CG   HG3  sing N N 273 
PRO CD   HD2  sing N N 274 
PRO CD   HD3  sing N N 275 
PRO OXT  HXT  sing N N 276 
SER N    CA   sing N N 277 
SER N    H    sing N N 278 
SER N    H2   sing N N 279 
SER CA   C    sing N N 280 
SER CA   CB   sing N N 281 
SER CA   HA   sing N N 282 
SER C    O    doub N N 283 
SER C    OXT  sing N N 284 
SER CB   OG   sing N N 285 
SER CB   HB2  sing N N 286 
SER CB   HB3  sing N N 287 
SER OG   HG   sing N N 288 
SER OXT  HXT  sing N N 289 
SRE CL19 C16  sing N N 290 
SRE C16  C17  sing Y N 291 
SRE C15  C16  doub Y N 292 
SRE C15  C14  sing Y N 293 
SRE CL20 C15  sing N N 294 
SRE C17  C18  doub Y N 295 
SRE C17  H17  sing N N 296 
SRE C18  H18  sing N N 297 
SRE C13  C18  sing Y N 298 
SRE C13  C4   sing N N 299 
SRE C14  C13  doub Y N 300 
SRE C14  H14  sing N N 301 
SRE C4   C3   sing N N 302 
SRE C4   C5   sing N N 303 
SRE C4   H4   sing N N 304 
SRE C5   C10  sing Y N 305 
SRE C6   C5   doub Y N 306 
SRE C6   C7   sing Y N 307 
SRE C6   H6   sing N N 308 
SRE C7   C8   doub Y N 309 
SRE C7   H7   sing N N 310 
SRE C8   C9   sing Y N 311 
SRE C8   H8   sing N N 312 
SRE C9   H9   sing N N 313 
SRE C10  C9   doub Y N 314 
SRE C10  C1   sing N N 315 
SRE C1   N11  sing N N 316 
SRE C1   H1   sing N N 317 
SRE N11  C12  sing N N 318 
SRE C12  H12  sing N N 319 
SRE C12  H12A sing N N 320 
SRE C2   C1   sing N N 321 
SRE C2   H2   sing N N 322 
SRE C2   H2A  sing N N 323 
SRE C3   C2   sing N N 324 
SRE C3   H3   sing N N 325 
SRE C3   H3A  sing N N 326 
SRE N11  H16  sing N N 327 
SRE C12  H171 sing N N 328 
THR N    CA   sing N N 329 
THR N    H    sing N N 330 
THR N    H2   sing N N 331 
THR CA   C    sing N N 332 
THR CA   CB   sing N N 333 
THR CA   HA   sing N N 334 
THR C    O    doub N N 335 
THR C    OXT  sing N N 336 
THR CB   OG1  sing N N 337 
THR CB   CG2  sing N N 338 
THR CB   HB   sing N N 339 
THR OG1  HG1  sing N N 340 
THR CG2  HG21 sing N N 341 
THR CG2  HG22 sing N N 342 
THR CG2  HG23 sing N N 343 
THR OXT  HXT  sing N N 344 
TRP N    CA   sing N N 345 
TRP N    H    sing N N 346 
TRP N    H2   sing N N 347 
TRP CA   C    sing N N 348 
TRP CA   CB   sing N N 349 
TRP CA   HA   sing N N 350 
TRP C    O    doub N N 351 
TRP C    OXT  sing N N 352 
TRP CB   CG   sing N N 353 
TRP CB   HB2  sing N N 354 
TRP CB   HB3  sing N N 355 
TRP CG   CD1  doub Y N 356 
TRP CG   CD2  sing Y N 357 
TRP CD1  NE1  sing Y N 358 
TRP CD1  HD1  sing N N 359 
TRP CD2  CE2  doub Y N 360 
TRP CD2  CE3  sing Y N 361 
TRP NE1  CE2  sing Y N 362 
TRP NE1  HE1  sing N N 363 
TRP CE2  CZ2  sing Y N 364 
TRP CE3  CZ3  doub Y N 365 
TRP CE3  HE3  sing N N 366 
TRP CZ2  CH2  doub Y N 367 
TRP CZ2  HZ2  sing N N 368 
TRP CZ3  CH2  sing Y N 369 
TRP CZ3  HZ3  sing N N 370 
TRP CH2  HH2  sing N N 371 
TRP OXT  HXT  sing N N 372 
TYR N    CA   sing N N 373 
TYR N    H    sing N N 374 
TYR N    H2   sing N N 375 
TYR CA   C    sing N N 376 
TYR CA   CB   sing N N 377 
TYR CA   HA   sing N N 378 
TYR C    O    doub N N 379 
TYR C    OXT  sing N N 380 
TYR CB   CG   sing N N 381 
TYR CB   HB2  sing N N 382 
TYR CB   HB3  sing N N 383 
TYR CG   CD1  doub Y N 384 
TYR CG   CD2  sing Y N 385 
TYR CD1  CE1  sing Y N 386 
TYR CD1  HD1  sing N N 387 
TYR CD2  CE2  doub Y N 388 
TYR CD2  HD2  sing N N 389 
TYR CE1  CZ   doub Y N 390 
TYR CE1  HE1  sing N N 391 
TYR CE2  CZ   sing Y N 392 
TYR CE2  HE2  sing N N 393 
TYR CZ   OH   sing N N 394 
TYR OH   HH   sing N N 395 
TYR OXT  HXT  sing N N 396 
VAL N    CA   sing N N 397 
VAL N    H    sing N N 398 
VAL N    H2   sing N N 399 
VAL CA   C    sing N N 400 
VAL CA   CB   sing N N 401 
VAL CA   HA   sing N N 402 
VAL C    O    doub N N 403 
VAL C    OXT  sing N N 404 
VAL CB   CG1  sing N N 405 
VAL CB   CG2  sing N N 406 
VAL CB   HB   sing N N 407 
VAL CG1  HG11 sing N N 408 
VAL CG1  HG12 sing N N 409 
VAL CG1  HG13 sing N N 410 
VAL CG2  HG21 sing N N 411 
VAL CG2  HG22 sing N N 412 
VAL CG2  HG23 sing N N 413 
VAL OXT  HXT  sing N N 414 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32171220 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   1NB8 
_pdbx_initial_refinement_model.details          'PDB code 1NB8 was used as a starting search model' 
# 
_atom_sites.entry_id                    9IJU 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009936 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000036 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011784 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009365 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N    . HIS A 1 3   ? 10.035  -0.681  46.079  1.00 95.16  ? 210 HIS A N    1 
ATOM   2     C  CA   . HIS A 1 3   ? 9.101   -1.291  45.098  1.00 97.21  ? 210 HIS A CA   1 
ATOM   3     C  C    . HIS A 1 3   ? 9.863   -2.242  44.178  1.00 94.80  ? 210 HIS A C    1 
ATOM   4     O  O    . HIS A 1 3   ? 9.334   -3.331  43.897  1.00 91.22  ? 210 HIS A O    1 
ATOM   5     C  CB   . HIS A 1 3   ? 8.377   -0.207  44.294  1.00 96.98  ? 210 HIS A CB   1 
ATOM   6     C  CG   . HIS A 1 3   ? 7.276   -0.741  43.444  1.00 101.51 ? 210 HIS A CG   1 
ATOM   7     N  ND1  . HIS A 1 3   ? 7.462   -1.068  42.116  1.00 98.73  ? 210 HIS A ND1  1 
ATOM   8     C  CD2  . HIS A 1 3   ? 5.987   -1.020  43.729  1.00 100.73 ? 210 HIS A CD2  1 
ATOM   9     C  CE1  . HIS A 1 3   ? 6.332   -1.521  41.616  1.00 104.49 ? 210 HIS A CE1  1 
ATOM   10    N  NE2  . HIS A 1 3   ? 5.410   -1.501  42.587  1.00 106.97 ? 210 HIS A NE2  1 
ATOM   11    N  N    . THR A 1 4   ? 11.060  -1.845  43.738  1.00 95.82  ? 211 THR A N    1 
ATOM   12    C  CA   . THR A 1 4   ? 11.794  -2.669  42.782  1.00 87.80  ? 211 THR A CA   1 
ATOM   13    C  C    . THR A 1 4   ? 12.986  -3.384  43.404  1.00 82.44  ? 211 THR A C    1 
ATOM   14    O  O    . THR A 1 4   ? 13.406  -4.430  42.889  1.00 81.99  ? 211 THR A O    1 
ATOM   15    C  CB   . THR A 1 4   ? 12.320  -1.808  41.638  1.00 78.82  ? 211 THR A CB   1 
ATOM   16    O  OG1  . THR A 1 4   ? 13.518  -1.154  42.080  1.00 75.75  ? 211 THR A OG1  1 
ATOM   17    C  CG2  . THR A 1 4   ? 11.293  -0.755  41.257  1.00 77.04  ? 211 THR A CG2  1 
ATOM   18    N  N    . GLY A 1 5   ? 13.582  -2.756  44.427  1.00 81.81  ? 212 GLY A N    1 
ATOM   19    C  CA   . GLY A 1 5   ? 14.824  -3.274  45.035  1.00 76.12  ? 212 GLY A CA   1 
ATOM   20    C  C    . GLY A 1 5   ? 16.007  -2.478  44.523  1.00 77.48  ? 212 GLY A C    1 
ATOM   21    O  O    . GLY A 1 5   ? 17.090  -2.601  45.117  1.00 72.22  ? 212 GLY A O    1 
ATOM   22    N  N    . TYR A 1 6   ? 15.806  -1.676  43.473  1.00 75.37  ? 213 TYR A N    1 
ATOM   23    C  CA   . TYR A 1 6   ? 16.857  -0.909  42.824  1.00 69.96  ? 213 TYR A CA   1 
ATOM   24    C  C    . TYR A 1 6   ? 16.467  0.558   42.822  1.00 68.71  ? 213 TYR A C    1 
ATOM   25    O  O    . TYR A 1 6   ? 15.286  0.899   42.748  1.00 66.73  ? 213 TYR A O    1 
ATOM   26    C  CB   . TYR A 1 6   ? 17.111  -1.378  41.363  1.00 63.19  ? 213 TYR A CB   1 
ATOM   27    C  CG   . TYR A 1 6   ? 17.329  -2.866  41.223  1.00 61.98  ? 213 TYR A CG   1 
ATOM   28    C  CD1  . TYR A 1 6   ? 18.424  -3.472  41.810  1.00 56.14  ? 213 TYR A CD1  1 
ATOM   29    C  CD2  . TYR A 1 6   ? 16.440  -3.667  40.506  1.00 62.63  ? 213 TYR A CD2  1 
ATOM   30    C  CE1  . TYR A 1 6   ? 18.637  -4.822  41.707  1.00 58.76  ? 213 TYR A CE1  1 
ATOM   31    C  CE2  . TYR A 1 6   ? 16.655  -5.033  40.390  1.00 60.17  ? 213 TYR A CE2  1 
ATOM   32    C  CZ   . TYR A 1 6   ? 17.763  -5.598  40.998  1.00 58.21  ? 213 TYR A CZ   1 
ATOM   33    O  OH   . TYR A 1 6   ? 18.024  -6.941  40.920  1.00 63.29  ? 213 TYR A OH   1 
ATOM   34    N  N    . VAL A 1 7   ? 17.493  1.391   42.895  1.00 67.63  ? 214 VAL A N    1 
ATOM   35    C  CA   . VAL A 1 7   ? 17.240  2.848   42.927  1.00 67.59  ? 214 VAL A CA   1 
ATOM   36    C  C    . VAL A 1 7   ? 17.582  3.461   41.580  1.00 67.00  ? 214 VAL A C    1 
ATOM   37    O  O    . VAL A 1 7   ? 18.391  2.886   40.836  1.00 67.87  ? 214 VAL A O    1 
ATOM   38    C  CB   . VAL A 1 7   ? 17.990  3.539   44.079  1.00 70.10  ? 214 VAL A CB   1 
ATOM   39    C  CG1  . VAL A 1 7   ? 17.365  3.219   45.424  1.00 73.45  ? 214 VAL A CG1  1 
ATOM   40    C  CG2  . VAL A 1 7   ? 19.469  3.235   44.087  1.00 69.69  ? 214 VAL A CG2  1 
ATOM   41    N  N    . GLY A 1 8   ? 16.926  4.568   41.279  1.00 63.13  ? 215 GLY A N    1 
ATOM   42    C  CA   . GLY A 1 8   ? 17.153  5.301   40.057  1.00 58.63  ? 215 GLY A CA   1 
ATOM   43    C  C    . GLY A 1 8   ? 18.226  6.339   40.247  1.00 61.27  ? 215 GLY A C    1 
ATOM   44    O  O    . GLY A 1 8   ? 18.877  6.423   41.289  1.00 67.12  ? 215 GLY A O    1 
ATOM   45    N  N    . LEU A 1 9   ? 18.424  7.130   39.195  1.00 66.43  ? 216 LEU A N    1 
ATOM   46    C  CA   . LEU A 1 9   ? 19.473  8.170   39.191  1.00 61.83  ? 216 LEU A CA   1 
ATOM   47    C  C    . LEU A 1 9   ? 18.843  9.486   38.763  1.00 64.29  ? 216 LEU A C    1 
ATOM   48    O  O    . LEU A 1 9   ? 18.108  9.494   37.795  1.00 62.75  ? 216 LEU A O    1 
ATOM   49    C  CB   . LEU A 1 9   ? 20.543  7.772   38.176  1.00 63.04  ? 216 LEU A CB   1 
ATOM   50    C  CG   . LEU A 1 9   ? 21.650  6.847   38.670  1.00 63.47  ? 216 LEU A CG   1 
ATOM   51    C  CD1  . LEU A 1 9   ? 22.303  6.131   37.505  1.00 61.95  ? 216 LEU A CD1  1 
ATOM   52    C  CD2  . LEU A 1 9   ? 22.696  7.620   39.444  1.00 60.78  ? 216 LEU A CD2  1 
ATOM   53    N  N    . LYS A 1 10  ? 19.205  10.580  39.413  1.00 69.61  ? 217 LYS A N    1 
ATOM   54    C  CA   . LYS A 1 10  ? 18.593  11.870  39.124  1.00 65.32  ? 217 LYS A CA   1 
ATOM   55    C  C    . LYS A 1 10  ? 19.001  12.339  37.740  1.00 62.04  ? 217 LYS A C    1 
ATOM   56    O  O    . LYS A 1 10  ? 20.128  12.118  37.294  1.00 66.86  ? 217 LYS A O    1 
ATOM   57    C  CB   . LYS A 1 10  ? 18.980  12.907  40.180  1.00 66.33  ? 217 LYS A CB   1 
ATOM   58    C  CG   . LYS A 1 10  ? 18.566  12.501  41.601  1.00 72.51  ? 217 LYS A CG   1 
ATOM   59    C  CD   . LYS A 1 10  ? 18.625  13.669  42.585  1.00 69.89  ? 217 LYS A CD   1 
ATOM   60    C  CE   . LYS A 1 10  ? 19.633  13.424  43.710  1.00 67.28  ? 217 LYS A CE   1 
ATOM   61    N  NZ   . LYS A 1 10  ? 20.506  14.636  43.916  1.00 63.75  ? 217 LYS A NZ   1 
ATOM   62    N  N    . ASN A 1 11  ? 18.053  12.939  37.040  1.00 66.17  ? 218 ASN A N    1 
ATOM   63    C  CA   . ASN A 1 11  ? 18.319  13.604  35.772  1.00 66.04  ? 218 ASN A CA   1 
ATOM   64    C  C    . ASN A 1 11  ? 18.767  15.030  36.076  1.00 70.93  ? 218 ASN A C    1 
ATOM   65    O  O    . ASN A 1 11  ? 17.955  15.868  36.493  1.00 69.73  ? 218 ASN A O    1 
ATOM   66    C  CB   . ASN A 1 11  ? 17.066  13.590  34.901  1.00 60.47  ? 218 ASN A CB   1 
ATOM   67    C  CG   . ASN A 1 11  ? 17.217  14.429  33.653  1.00 65.49  ? 218 ASN A CG   1 
ATOM   68    O  OD1  . ASN A 1 11  ? 18.331  14.785  33.264  1.00 64.66  ? 218 ASN A OD1  1 
ATOM   69    N  ND2  . ASN A 1 11  ? 16.097  14.733  33.003  1.00 67.28  ? 218 ASN A ND2  1 
ATOM   70    N  N    . GLN A 1 12  ? 20.046  15.310  35.845  1.00 63.53  ? 219 GLN A N    1 
ATOM   71    C  CA   . GLN A 1 12  ? 20.554  16.686  36.070  1.00 68.88  ? 219 GLN A CA   1 
ATOM   72    C  C    . GLN A 1 12  ? 19.844  17.633  35.108  1.00 65.38  ? 219 GLN A C    1 
ATOM   73    O  O    . GLN A 1 12  ? 19.693  18.792  35.467  1.00 73.54  ? 219 GLN A O    1 
ATOM   74    C  CB   . GLN A 1 12  ? 22.069  16.758  35.890  1.00 67.85  ? 219 GLN A CB   1 
ATOM   75    C  CG   . GLN A 1 12  ? 22.857  16.023  36.960  1.00 71.78  ? 219 GLN A CG   1 
ATOM   76    C  CD   . GLN A 1 12  ? 24.337  16.271  36.810  1.00 73.90  ? 219 GLN A CD   1 
ATOM   77    O  OE1  . GLN A 1 12  ? 25.107  15.374  36.483  1.00 75.12  ? 219 GLN A OE1  1 
ATOM   78    N  NE2  . GLN A 1 12  ? 24.746  17.507  37.037  1.00 73.94  ? 219 GLN A NE2  1 
ATOM   79    N  N    . GLY A 1 13  ? 19.416  17.144  33.944  1.00 67.29  ? 220 GLY A N    1 
ATOM   80    C  CA   . GLY A 1 13  ? 18.664  17.954  32.963  1.00 65.05  ? 220 GLY A CA   1 
ATOM   81    C  C    . GLY A 1 13  ? 18.614  17.275  31.611  1.00 64.57  ? 220 GLY A C    1 
ATOM   82    O  O    . GLY A 1 13  ? 17.518  17.204  31.036  1.00 64.92  ? 220 GLY A O    1 
ATOM   83    N  N    . ALA A 1 14  ? 19.756  16.800  31.123  1.00 62.76  ? 221 ALA A N    1 
ATOM   84    C  CA   . ALA A 1 14  ? 19.845  16.072  29.865  1.00 64.47  ? 221 ALA A CA   1 
ATOM   85    C  C    . ALA A 1 14  ? 20.706  14.821  30.001  1.00 67.98  ? 221 ALA A C    1 
ATOM   86    O  O    . ALA A 1 14  ? 21.102  14.235  28.991  1.00 64.85  ? 221 ALA A O    1 
ATOM   87    C  CB   . ALA A 1 14  ? 20.396  16.964  28.750  1.00 66.46  ? 221 ALA A CB   1 
ATOM   88    N  N    . THR A 1 15  ? 20.960  14.404  31.244  1.00 63.98  ? 222 THR A N    1 
ATOM   89    C  CA   . THR A 1 15  ? 21.901  13.294  31.527  1.00 60.75  ? 222 THR A CA   1 
ATOM   90    C  C    . THR A 1 15  ? 21.236  11.921  31.484  1.00 61.23  ? 222 THR A C    1 
ATOM   91    O  O    . THR A 1 15  ? 21.766  11.013  32.129  1.00 57.24  ? 222 THR A O    1 
ATOM   92    C  CB   . THR A 1 15  ? 22.556  13.558  32.886  1.00 67.55  ? 222 THR A CB   1 
ATOM   93    O  OG1  . THR A 1 15  ? 21.550  13.544  33.899  1.00 69.06  ? 222 THR A OG1  1 
ATOM   94    C  CG2  . THR A 1 15  ? 23.306  14.870  32.919  1.00 61.90  ? 222 THR A CG2  1 
ATOM   95    N  N    . CYS A 1 16  ? 20.164  11.766  30.712  1.00 56.55  ? 223 CYS A N    1 
ATOM   96    C  CA   . CYS A 1 16  ? 19.506  10.441  30.551  1.00 56.72  ? 223 CYS A CA   1 
ATOM   97    C  C    . CYS A 1 16  ? 20.527  9.439   30.011  1.00 60.56  ? 223 CYS A C    1 
ATOM   98    O  O    . CYS A 1 16  ? 20.545  8.308   30.502  1.00 56.26  ? 223 CYS A O    1 
ATOM   99    C  CB   . CYS A 1 16  ? 18.320  10.516  29.598  1.00 48.61  ? 223 CYS A CB   1 
ATOM   100   S  SG   . CYS A 1 16  ? 18.095  12.119  28.794  1.00 62.29  ? 223 CYS A SG   1 
ATOM   101   N  N    . TYR A 1 17  ? 21.341  9.854   29.041  1.00 57.07  ? 224 TYR A N    1 
ATOM   102   C  CA   . TYR A 1 17  ? 22.383  8.979   28.455  1.00 58.74  ? 224 TYR A CA   1 
ATOM   103   C  C    . TYR A 1 17  ? 23.279  8.424   29.559  1.00 55.97  ? 224 TYR A C    1 
ATOM   104   O  O    . TYR A 1 17  ? 23.465  7.208   29.599  1.00 54.96  ? 224 TYR A O    1 
ATOM   105   C  CB   . TYR A 1 17  ? 23.176  9.746   27.390  1.00 58.77  ? 224 TYR A CB   1 
ATOM   106   C  CG   . TYR A 1 17  ? 23.944  10.956  27.854  1.00 57.67  ? 224 TYR A CG   1 
ATOM   107   C  CD1  . TYR A 1 17  ? 23.321  12.180  27.998  1.00 58.04  ? 224 TYR A CD1  1 
ATOM   108   C  CD2  . TYR A 1 17  ? 25.298  10.884  28.134  1.00 55.39  ? 224 TYR A CD2  1 
ATOM   109   C  CE1  . TYR A 1 17  ? 24.015  13.296  28.428  1.00 57.94  ? 224 TYR A CE1  1 
ATOM   110   C  CE2  . TYR A 1 17  ? 26.006  11.986  28.579  1.00 60.04  ? 224 TYR A CE2  1 
ATOM   111   C  CZ   . TYR A 1 17  ? 25.359  13.198  28.722  1.00 61.43  ? 224 TYR A CZ   1 
ATOM   112   O  OH   . TYR A 1 17  ? 26.027  14.306  29.139  1.00 61.34  ? 224 TYR A OH   1 
ATOM   113   N  N    . MET A 1 18  ? 23.788  9.292   30.429  1.00 56.32  ? 225 MET A N    1 
ATOM   114   C  CA   . MET A 1 18  ? 24.749  8.862   31.468  1.00 57.82  ? 225 MET A CA   1 
ATOM   115   C  C    . MET A 1 18  ? 24.043  7.903   32.407  1.00 60.60  ? 225 MET A C    1 
ATOM   116   O  O    . MET A 1 18  ? 24.571  6.835   32.612  1.00 59.22  ? 225 MET A O    1 
ATOM   117   C  CB   . MET A 1 18  ? 25.270  10.058  32.262  1.00 54.24  ? 225 MET A CB   1 
ATOM   118   C  CG   . MET A 1 18  ? 26.633  9.835   32.864  1.00 56.23  ? 225 MET A CG   1 
ATOM   119   S  SD   . MET A 1 18  ? 27.267  11.336  33.625  1.00 70.29  ? 225 MET A SD   1 
ATOM   120   C  CE   . MET A 1 18  ? 25.745  12.054  34.230  1.00 59.33  ? 225 MET A CE   1 
ATOM   121   N  N    . ASN A 1 19  ? 22.880  8.287   32.908  1.00 58.16  ? 226 ASN A N    1 
ATOM   122   C  CA   . ASN A 1 19  ? 22.150  7.451   33.887  1.00 58.12  ? 226 ASN A CA   1 
ATOM   123   C  C    . ASN A 1 19  ? 21.932  6.058   33.288  1.00 54.93  ? 226 ASN A C    1 
ATOM   124   O  O    . ASN A 1 19  ? 22.169  5.091   33.997  1.00 56.83  ? 226 ASN A O    1 
ATOM   125   C  CB   . ASN A 1 19  ? 20.879  8.164   34.354  1.00 61.60  ? 226 ASN A CB   1 
ATOM   126   C  CG   . ASN A 1 19  ? 21.133  9.545   34.920  1.00 69.46  ? 226 ASN A CG   1 
ATOM   127   O  OD1  . ASN A 1 19  ? 22.129  9.774   35.600  1.00 69.93  ? 226 ASN A OD1  1 
ATOM   128   N  ND2  . ASN A 1 19  ? 20.236  10.474  34.643  1.00 68.78  ? 226 ASN A ND2  1 
ATOM   129   N  N    . SER A 1 20  ? 21.517  5.969   32.025  1.00 56.80  ? 227 SER A N    1 
ATOM   130   C  CA   . SER A 1 20  ? 21.248  4.662   31.432  1.00 57.69  ? 227 SER A CA   1 
ATOM   131   C  C    . SER A 1 20  ? 22.532  3.883   31.253  1.00 53.99  ? 227 SER A C    1 
ATOM   132   O  O    . SER A 1 20  ? 22.564  2.672   31.507  1.00 53.76  ? 227 SER A O    1 
ATOM   133   C  CB   . SER A 1 20  ? 20.503  4.791   30.106  1.00 56.53  ? 227 SER A CB   1 
ATOM   134   O  OG   . SER A 1 20  ? 19.489  5.770   30.190  1.00 60.25  ? 227 SER A OG   1 
ATOM   135   N  N    . LEU A 1 21  ? 23.608  4.565   30.841  1.00 52.00  ? 228 LEU A N    1 
ATOM   136   C  CA   . LEU A 1 21  ? 24.900  3.900   30.810  1.00 52.08  ? 228 LEU A CA   1 
ATOM   137   C  C    . LEU A 1 21  ? 25.325  3.505   32.208  1.00 51.14  ? 228 LEU A C    1 
ATOM   138   O  O    . LEU A 1 21  ? 25.807  2.387   32.422  1.00 53.36  ? 228 LEU A O    1 
ATOM   139   C  CB   . LEU A 1 21  ? 25.961  4.789   30.170  1.00 57.90  ? 228 LEU A CB   1 
ATOM   140   C  CG   . LEU A 1 21  ? 27.346  4.122   30.220  1.00 50.63  ? 228 LEU A CG   1 
ATOM   141   C  CD1  . LEU A 1 21  ? 27.451  2.952   29.247  1.00 47.81  ? 228 LEU A CD1  1 
ATOM   142   C  CD2  . LEU A 1 21  ? 28.491  5.105   29.982  1.00 49.84  ? 228 LEU A CD2  1 
ATOM   143   N  N    . LEU A 1 22  ? 25.139  4.387   33.181  1.00 56.33  ? 229 LEU A N    1 
ATOM   144   C  CA   . LEU A 1 22  ? 25.638  4.102   34.549  1.00 53.09  ? 229 LEU A CA   1 
ATOM   145   C  C    . LEU A 1 22  ? 24.926  2.881   35.113  1.00 55.80  ? 229 LEU A C    1 
ATOM   146   O  O    . LEU A 1 22  ? 25.628  2.018   35.594  1.00 54.72  ? 229 LEU A O    1 
ATOM   147   C  CB   . LEU A 1 22  ? 25.451  5.325   35.444  1.00 53.54  ? 229 LEU A CB   1 
ATOM   148   C  CG   . LEU A 1 22  ? 26.471  6.438   35.239  1.00 57.01  ? 229 LEU A CG   1 
ATOM   149   C  CD1  . LEU A 1 22  ? 26.096  7.658   36.055  1.00 56.28  ? 229 LEU A CD1  1 
ATOM   150   C  CD2  . LEU A 1 22  ? 27.863  5.959   35.595  1.00 49.22  ? 229 LEU A CD2  1 
ATOM   151   N  N    . GLN A 1 23  ? 23.598  2.816   35.042  1.00 54.12  ? 230 GLN A N    1 
ATOM   152   C  CA   . GLN A 1 23  ? 22.913  1.601   35.494  1.00 53.61  ? 230 GLN A CA   1 
ATOM   153   C  C    . GLN A 1 23  ? 23.451  0.379   34.764  1.00 51.03  ? 230 GLN A C    1 
ATOM   154   O  O    . GLN A 1 23  ? 23.692  -0.670  35.379  1.00 50.26  ? 230 GLN A O    1 
ATOM   155   C  CB   . GLN A 1 23  ? 21.394  1.712   35.289  1.00 52.52  ? 230 GLN A CB   1 
ATOM   156   C  CG   . GLN A 1 23  ? 20.743  2.975   35.853  1.00 50.81  ? 230 GLN A CG   1 
ATOM   157   C  CD   . GLN A 1 23  ? 20.431  2.846   37.334  1.00 56.23  ? 230 GLN A CD   1 
ATOM   158   O  OE1  . GLN A 1 23  ? 20.840  1.876   37.969  1.00 54.77  ? 230 GLN A OE1  1 
ATOM   159   N  NE2  . GLN A 1 23  ? 19.701  3.822   37.891  1.00 54.36  ? 230 GLN A NE2  1 
ATOM   160   N  N    . THR A 1 24  ? 23.675  0.513   33.452  1.00 49.18  ? 231 THR A N    1 
ATOM   161   C  CA   . THR A 1 24  ? 24.207  -0.593  32.663  1.00 49.26  ? 231 THR A CA   1 
ATOM   162   C  C    . THR A 1 24  ? 25.544  -1.080  33.221  1.00 48.86  ? 231 THR A C    1 
ATOM   163   O  O    . THR A 1 24  ? 25.732  -2.274  33.477  1.00 45.31  ? 231 THR A O    1 
ATOM   164   C  CB   . THR A 1 24  ? 24.348  -0.148  31.212  1.00 49.96  ? 231 THR A CB   1 
ATOM   165   O  OG1  . THR A 1 24  ? 23.061  0.286   30.720  1.00 53.13  ? 231 THR A OG1  1 
ATOM   166   C  CG2  . THR A 1 24  ? 24.890  -1.282  30.352  1.00 45.32  ? 231 THR A CG2  1 
ATOM   167   N  N    . LEU A 1 25  ? 26.479  -0.162  33.444  1.00 50.35  ? 232 LEU A N    1 
ATOM   168   C  CA   . LEU A 1 25  ? 27.761  -0.554  34.017  1.00 49.76  ? 232 LEU A CA   1 
ATOM   169   C  C    . LEU A 1 25  ? 27.618  -0.948  35.482  1.00 52.77  ? 232 LEU A C    1 
ATOM   170   O  O    . LEU A 1 25  ? 28.287  -1.879  35.956  1.00 54.53  ? 232 LEU A O    1 
ATOM   171   C  CB   . LEU A 1 25  ? 28.760  0.590   33.854  1.00 48.91  ? 232 LEU A CB   1 
ATOM   172   C  CG   . LEU A 1 25  ? 28.992  1.009   32.390  1.00 52.24  ? 232 LEU A CG   1 
ATOM   173   C  CD1  . LEU A 1 25  ? 29.965  2.182   32.302  1.00 38.44  ? 232 LEU A CD1  1 
ATOM   174   C  CD2  . LEU A 1 25  ? 29.476  -0.194  31.557  1.00 44.81  ? 232 LEU A CD2  1 
ATOM   175   N  N    . PHE A 1 26  ? 26.751  -0.257  36.220  1.00 54.79  ? 233 PHE A N    1 
ATOM   176   C  CA   . PHE A 1 26  ? 26.554  -0.611  37.617  1.00 55.65  ? 233 PHE A CA   1 
ATOM   177   C  C    . PHE A 1 26  ? 26.190  -2.080  37.750  1.00 55.78  ? 233 PHE A C    1 
ATOM   178   O  O    . PHE A 1 26  ? 26.814  -2.810  38.528  1.00 55.81  ? 233 PHE A O    1 
ATOM   179   C  CB   . PHE A 1 26  ? 25.487  0.277   38.250  1.00 55.62  ? 233 PHE A CB   1 
ATOM   180   C  CG   . PHE A 1 26  ? 25.114  -0.129  39.634  1.00 57.80  ? 233 PHE A CG   1 
ATOM   181   C  CD1  . PHE A 1 26  ? 26.004  0.069   40.696  1.00 63.50  ? 233 PHE A CD1  1 
ATOM   182   C  CD2  . PHE A 1 26  ? 23.877  -0.714  39.893  1.00 58.41  ? 233 PHE A CD2  1 
ATOM   183   C  CE1  . PHE A 1 26  ? 25.661  -0.305  42.015  1.00 63.50  ? 233 PHE A CE1  1 
ATOM   184   C  CE2  . PHE A 1 26  ? 23.525  -1.100  41.206  1.00 64.30  ? 233 PHE A CE2  1 
ATOM   185   C  CZ   . PHE A 1 26  ? 24.423  -0.889  42.272  1.00 62.50  ? 233 PHE A CZ   1 
ATOM   186   N  N    . PHE A 1 27  ? 25.217  -2.554  36.966  1.00 52.89  ? 234 PHE A N    1 
ATOM   187   C  CA   . PHE A 1 27  ? 24.877  -3.974  37.095  1.00 56.68  ? 234 PHE A CA   1 
ATOM   188   C  C    . PHE A 1 27  ? 25.801  -4.896  36.302  1.00 57.18  ? 234 PHE A C    1 
ATOM   189   O  O    . PHE A 1 27  ? 25.543  -6.103  36.252  1.00 62.21  ? 234 PHE A O    1 
ATOM   190   C  CB   . PHE A 1 27  ? 23.422  -4.240  36.697  1.00 52.21  ? 234 PHE A CB   1 
ATOM   191   C  CG   . PHE A 1 27  ? 22.426  -3.538  37.562  1.00 49.80  ? 234 PHE A CG   1 
ATOM   192   C  CD1  . PHE A 1 27  ? 22.198  -3.958  38.867  1.00 55.01  ? 234 PHE A CD1  1 
ATOM   193   C  CD2  . PHE A 1 27  ? 21.723  -2.452  37.080  1.00 51.34  ? 234 PHE A CD2  1 
ATOM   194   C  CE1  . PHE A 1 27  ? 21.285  -3.301  39.688  1.00 52.73  ? 234 PHE A CE1  1 
ATOM   195   C  CE2  . PHE A 1 27  ? 20.810  -1.789  37.887  1.00 55.56  ? 234 PHE A CE2  1 
ATOM   196   C  CZ   . PHE A 1 27  ? 20.591  -2.219  39.198  1.00 55.96  ? 234 PHE A CZ   1 
ATOM   197   N  N    . THR A 1 28  ? 26.859  -4.390  35.679  1.00 53.00  ? 235 THR A N    1 
ATOM   198   C  CA   . THR A 1 28  ? 27.955  -5.276  35.302  1.00 48.98  ? 235 THR A CA   1 
ATOM   199   C  C    . THR A 1 28  ? 28.738  -5.476  36.594  1.00 53.93  ? 235 THR A C    1 
ATOM   200   O  O    . THR A 1 28  ? 29.682  -4.733  36.901  1.00 54.38  ? 235 THR A O    1 
ATOM   201   C  CB   . THR A 1 28  ? 28.812  -4.675  34.189  1.00 48.13  ? 235 THR A CB   1 
ATOM   202   O  OG1  . THR A 1 28  ? 27.985  -4.099  33.177  1.00 41.69  ? 235 THR A OG1  1 
ATOM   203   C  CG2  . THR A 1 28  ? 29.706  -5.729  33.566  1.00 45.83  ? 235 THR A CG2  1 
ATOM   204   N  N    . ASN A 1 29  ? 28.313  -6.467  37.385  1.00 54.03  ? 236 ASN A N    1 
ATOM   205   C  CA   . ASN A 1 29  ? 28.775  -6.577  38.771  1.00 56.11  ? 236 ASN A CA   1 
ATOM   206   C  C    . ASN A 1 29  ? 30.286  -6.674  38.852  1.00 56.45  ? 236 ASN A C    1 
ATOM   207   O  O    . ASN A 1 29  ? 30.921  -5.978  39.658  1.00 57.16  ? 236 ASN A O    1 
ATOM   208   C  CB   . ASN A 1 29  ? 28.155  -7.791  39.455  1.00 56.07  ? 236 ASN A CB   1 
ATOM   209   C  CG   . ASN A 1 29  ? 26.740  -7.551  39.848  1.00 58.44  ? 236 ASN A CG   1 
ATOM   210   O  OD1  . ASN A 1 29  ? 26.147  -6.564  39.408  1.00 51.75  ? 236 ASN A OD1  1 
ATOM   211   N  ND2  . ASN A 1 29  ? 26.182  -8.433  40.699  1.00 51.72  ? 236 ASN A ND2  1 
ATOM   212   N  N    . GLN A 1 30  ? 30.877  -7.559  38.041  1.00 50.77  ? 237 GLN A N    1 
ATOM   213   C  CA   . GLN A 1 30  ? 32.324  -7.726  38.067  1.00 49.38  ? 237 GLN A CA   1 
ATOM   214   C  C    . GLN A 1 30  ? 33.058  -6.411  37.792  1.00 53.94  ? 237 GLN A C    1 
ATOM   215   O  O    . GLN A 1 30  ? 34.123  -6.163  38.363  1.00 53.00  ? 237 GLN A O    1 
ATOM   216   C  CB   . GLN A 1 30  ? 32.734  -8.796  37.069  1.00 49.59  ? 237 GLN A CB   1 
ATOM   217   C  CG   . GLN A 1 30  ? 34.188  -9.202  37.214  1.00 58.35  ? 237 GLN A CG   1 
ATOM   218   C  CD   . GLN A 1 30  ? 34.539  -10.437 36.406  1.00 59.99  ? 237 GLN A CD   1 
ATOM   219   O  OE1  . GLN A 1 30  ? 33.660  -11.155 35.955  1.00 59.32  ? 237 GLN A OE1  1 
ATOM   220   N  NE2  . GLN A 1 30  ? 35.830  -10.683 36.220  1.00 64.68  ? 237 GLN A NE2  1 
ATOM   221   N  N    . LEU A 1 31  ? 32.496  -5.538  36.957  1.00 52.50  ? 238 LEU A N    1 
ATOM   222   C  CA   . LEU A 1 31  ? 33.124  -4.240  36.740  1.00 54.48  ? 238 LEU A CA   1 
ATOM   223   C  C    . LEU A 1 31  ? 33.014  -3.370  37.985  1.00 51.07  ? 238 LEU A C    1 
ATOM   224   O  O    . LEU A 1 31  ? 33.988  -2.730  38.391  1.00 56.87  ? 238 LEU A O    1 
ATOM   225   C  CB   . LEU A 1 31  ? 32.488  -3.559  35.526  1.00 47.46  ? 238 LEU A CB   1 
ATOM   226   C  CG   . LEU A 1 31  ? 32.892  -2.139  35.178  1.00 46.85  ? 238 LEU A CG   1 
ATOM   227   C  CD1  . LEU A 1 31  ? 34.407  -2.004  35.137  1.00 53.87  ? 238 LEU A CD1  1 
ATOM   228   C  CD2  . LEU A 1 31  ? 32.306  -1.736  33.853  1.00 43.62  ? 238 LEU A CD2  1 
ATOM   229   N  N    . ARG A 1 32  ? 31.835  -3.345  38.607  1.00 57.89  ? 239 ARG A N    1 
ATOM   230   C  CA   . ARG A 1 32  ? 31.620  -2.518  39.789  1.00 52.48  ? 239 ARG A CA   1 
ATOM   231   C  C    . ARG A 1 32  ? 32.524  -2.967  40.925  1.00 57.52  ? 239 ARG A C    1 
ATOM   232   O  O    . ARG A 1 32  ? 33.134  -2.132  41.611  1.00 58.41  ? 239 ARG A O    1 
ATOM   233   C  CB   . ARG A 1 32  ? 30.149  -2.584  40.194  1.00 54.39  ? 239 ARG A CB   1 
ATOM   234   C  CG   . ARG A 1 32  ? 29.702  -1.579  41.216  1.00 53.46  ? 239 ARG A CG   1 
ATOM   235   C  CD   . ARG A 1 32  ? 28.720  -2.229  42.185  1.00 59.40  ? 239 ARG A CD   1 
ATOM   236   N  NE   . ARG A 1 32  ? 27.516  -2.725  41.523  1.00 60.12  ? 239 ARG A NE   1 
ATOM   237   C  CZ   . ARG A 1 32  ? 26.594  -3.490  42.110  1.00 60.65  ? 239 ARG A CZ   1 
ATOM   238   N  NH1  . ARG A 1 32  ? 26.727  -3.854  43.386  1.00 58.67  ? 239 ARG A NH1  1 
ATOM   239   N  NH2  . ARG A 1 32  ? 25.528  -3.883  41.418  1.00 57.36  ? 239 ARG A NH2  1 
ATOM   240   N  N    . LYS A 1 33  ? 32.636  -4.290  41.122  1.00 58.08  ? 240 LYS A N    1 
ATOM   241   C  CA   . LYS A 1 33  ? 33.612  -4.846  42.060  1.00 58.33  ? 240 LYS A CA   1 
ATOM   242   C  C    . LYS A 1 33  ? 35.000  -4.282  41.809  1.00 55.50  ? 240 LYS A C    1 
ATOM   243   O  O    . LYS A 1 33  ? 35.714  -3.931  42.751  1.00 63.93  ? 240 LYS A O    1 
ATOM   244   C  CB   . LYS A 1 33  ? 33.657  -6.375  41.953  1.00 53.30  ? 240 LYS A CB   1 
ATOM   245   C  CG   . LYS A 1 33  ? 32.984  -7.121  43.087  1.00 59.47  ? 240 LYS A CG   1 
ATOM   246   C  CD   . LYS A 1 33  ? 33.325  -8.608  43.052  1.00 63.52  ? 240 LYS A CD   1 
ATOM   247   N  N    . ALA A 1 34  ? 35.411  -4.198  40.545  1.00 59.02  ? 241 ALA A N    1 
ATOM   248   C  CA   . ALA A 1 34  ? 36.756  -3.706  40.266  1.00 58.07  ? 241 ALA A CA   1 
ATOM   249   C  C    . ALA A 1 34  ? 36.859  -2.198  40.441  1.00 56.12  ? 241 ALA A C    1 
ATOM   250   O  O    . ALA A 1 34  ? 37.906  -1.705  40.869  1.00 54.82  ? 241 ALA A O    1 
ATOM   251   C  CB   . ALA A 1 34  ? 37.202  -4.108  38.861  1.00 52.33  ? 241 ALA A CB   1 
ATOM   252   N  N    . VAL A 1 35  ? 35.795  -1.447  40.145  1.00 57.32  ? 242 VAL A N    1 
ATOM   253   C  CA   . VAL A 1 35  ? 35.859  0.001   40.350  1.00 57.20  ? 242 VAL A CA   1 
ATOM   254   C  C    . VAL A 1 35  ? 36.005  0.327   41.839  1.00 59.30  ? 242 VAL A C    1 
ATOM   255   O  O    . VAL A 1 35  ? 36.800  1.198   42.225  1.00 57.71  ? 242 VAL A O    1 
ATOM   256   C  CB   . VAL A 1 35  ? 34.628  0.681   39.726  1.00 52.85  ? 242 VAL A CB   1 
ATOM   257   C  CG1  . VAL A 1 35  ? 34.488  2.110   40.233  1.00 52.63  ? 242 VAL A CG1  1 
ATOM   258   C  CG2  . VAL A 1 35  ? 34.710  0.650   38.208  1.00 46.90  ? 242 VAL A CG2  1 
ATOM   259   N  N    . TYR A 1 36  ? 35.261  -0.379  42.699  1.00 53.82  ? 243 TYR A N    1 
ATOM   260   C  CA   . TYR A 1 36  ? 35.419  -0.193  44.143  1.00 60.50  ? 243 TYR A CA   1 
ATOM   261   C  C    . TYR A 1 36  ? 36.859  -0.424  44.602  1.00 57.52  ? 243 TYR A C    1 
ATOM   262   O  O    . TYR A 1 36  ? 37.284  0.145   45.608  1.00 61.32  ? 243 TYR A O    1 
ATOM   263   C  CB   . TYR A 1 36  ? 34.504  -1.152  44.918  1.00 62.42  ? 243 TYR A CB   1 
ATOM   264   C  CG   . TYR A 1 36  ? 33.030  -0.824  44.918  1.00 55.73  ? 243 TYR A CG   1 
ATOM   265   C  CD1  . TYR A 1 36  ? 32.587  0.483   44.935  1.00 56.21  ? 243 TYR A CD1  1 
ATOM   266   C  CD2  . TYR A 1 36  ? 32.083  -1.842  44.908  1.00 56.45  ? 243 TYR A CD2  1 
ATOM   267   C  CE1  . TYR A 1 36  ? 31.234  0.765   44.939  1.00 60.44  ? 243 TYR A CE1  1 
ATOM   268   C  CE2  . TYR A 1 36  ? 30.739  -1.575  44.912  1.00 52.38  ? 243 TYR A CE2  1 
ATOM   269   C  CZ   . TYR A 1 36  ? 30.317  -0.274  44.932  1.00 58.54  ? 243 TYR A CZ   1 
ATOM   270   O  OH   . TYR A 1 36  ? 28.966  -0.002  44.937  1.00 64.61  ? 243 TYR A OH   1 
ATOM   271   N  N    . MET A 1 37  ? 37.609  -1.269  43.902  1.00 55.97  ? 244 MET A N    1 
ATOM   272   C  CA   . MET A 1 37  ? 38.951  -1.652  44.311  1.00 57.82  ? 244 MET A CA   1 
ATOM   273   C  C    . MET A 1 37  ? 40.028  -0.749  43.725  1.00 61.36  ? 244 MET A C    1 
ATOM   274   O  O    . MET A 1 37  ? 41.225  -0.992  43.959  1.00 60.02  ? 244 MET A O    1 
ATOM   275   C  CB   . MET A 1 37  ? 39.225  -3.105  43.914  1.00 57.34  ? 244 MET A CB   1 
ATOM   276   C  CG   . MET A 1 37  ? 38.535  -4.139  44.806  1.00 60.21  ? 244 MET A CG   1 
ATOM   277   S  SD   . MET A 1 37  ? 39.269  -5.784  44.611  1.00 82.94  ? 244 MET A SD   1 
ATOM   278   C  CE   . MET A 1 37  ? 38.698  -6.257  42.971  1.00 69.86  ? 244 MET A CE   1 
ATOM   279   N  N    . MET A 1 38  ? 39.624  0.276   42.982  1.00 58.45  ? 245 MET A N    1 
ATOM   280   C  CA   . MET A 1 38  ? 40.607  1.205   42.374  1.00 62.46  ? 245 MET A CA   1 
ATOM   281   C  C    . MET A 1 38  ? 41.130  2.156   43.453  1.00 59.21  ? 245 MET A C    1 
ATOM   282   O  O    . MET A 1 38  ? 40.312  2.726   44.184  1.00 54.87  ? 245 MET A O    1 
ATOM   283   C  CB   . MET A 1 38  ? 39.977  2.020   41.247  1.00 57.26  ? 245 MET A CB   1 
ATOM   284   C  CG   . MET A 1 38  ? 39.567  1.198   40.059  1.00 58.83  ? 245 MET A CG   1 
ATOM   285   S  SD   . MET A 1 38  ? 38.789  2.256   38.834  1.00 58.78  ? 245 MET A SD   1 
ATOM   286   C  CE   . MET A 1 38  ? 40.249  2.998   38.114  1.00 54.21  ? 245 MET A CE   1 
ATOM   287   N  N    . PRO A 1 39  ? 42.461  2.346   43.576  1.00 60.57  ? 246 PRO A N    1 
ATOM   288   C  CA   . PRO A 1 39  ? 43.024  3.255   44.591  1.00 58.44  ? 246 PRO A CA   1 
ATOM   289   C  C    . PRO A 1 39  ? 42.742  4.725   44.364  1.00 63.36  ? 246 PRO A C    1 
ATOM   290   O  O    . PRO A 1 39  ? 43.489  5.373   43.633  1.00 73.48  ? 246 PRO A O    1 
ATOM   291   C  CB   . PRO A 1 39  ? 44.533  3.004   44.479  1.00 61.75  ? 246 PRO A CB   1 
ATOM   292   C  CG   . PRO A 1 39  ? 44.723  2.490   43.091  1.00 60.28  ? 246 PRO A CG   1 
ATOM   293   C  CD   . PRO A 1 39  ? 43.511  1.648   42.819  1.00 59.61  ? 246 PRO A CD   1 
ATOM   294   N  N    . THR A 1 40  ? 41.704  5.272   45.001  1.00 70.43  ? 247 THR A N    1 
ATOM   295   C  CA   . THR A 1 40  ? 41.432  6.704   44.983  1.00 74.18  ? 247 THR A CA   1 
ATOM   296   C  C    . THR A 1 40  ? 41.852  7.390   46.277  1.00 74.68  ? 247 THR A C    1 
ATOM   297   O  O    . THR A 1 40  ? 41.294  8.439   46.627  1.00 78.87  ? 247 THR A O    1 
ATOM   298   C  CB   . THR A 1 40  ? 39.946  6.972   44.715  1.00 75.75  ? 247 THR A CB   1 
ATOM   299   O  OG1  . THR A 1 40  ? 39.151  6.404   45.773  1.00 72.59  ? 247 THR A OG1  1 
ATOM   300   C  CG2  . THR A 1 40  ? 39.519  6.408   43.349  1.00 65.53  ? 247 THR A CG2  1 
ATOM   301   N  N    . GLU A 1 41  ? 42.811  6.815   47.005  1.00 78.66  ? 248 GLU A N    1 
ATOM   302   C  CA   . GLU A 1 41  ? 43.329  7.482   48.195  1.00 82.67  ? 248 GLU A CA   1 
ATOM   303   C  C    . GLU A 1 41  ? 43.998  8.798   47.815  1.00 80.60  ? 248 GLU A C    1 
ATOM   304   O  O    . GLU A 1 41  ? 43.534  9.884   48.188  1.00 80.91  ? 248 GLU A O    1 
ATOM   305   C  CB   . GLU A 1 41  ? 44.301  6.556   48.931  1.00 69.98  ? 248 GLU A CB   1 
ATOM   306   N  N    . ASP A 1 43  ? 43.899  10.382  45.164  1.00 92.13  ? 250 ASP A N    1 
ATOM   307   C  CA   . ASP A 1 43  ? 43.166  11.041  44.093  1.00 84.88  ? 250 ASP A CA   1 
ATOM   308   C  C    . ASP A 1 43  ? 42.505  12.312  44.614  1.00 87.83  ? 250 ASP A C    1 
ATOM   309   O  O    . ASP A 1 43  ? 41.938  12.328  45.712  1.00 87.57  ? 250 ASP A O    1 
ATOM   310   C  CB   . ASP A 1 43  ? 42.122  10.094  43.495  1.00 79.52  ? 250 ASP A CB   1 
ATOM   311   C  CG   . ASP A 1 43  ? 42.689  9.246   42.373  1.00 82.92  ? 250 ASP A CG   1 
ATOM   312   O  OD1  . ASP A 1 43  ? 43.903  9.368   42.100  1.00 90.00  ? 250 ASP A OD1  1 
ATOM   313   O  OD2  . ASP A 1 43  ? 41.933  8.474   41.745  1.00 79.98  ? 250 ASP A OD2  1 
ATOM   314   N  N    . ASP A 1 44  ? 42.598  13.384  43.825  1.00 86.90  ? 251 ASP A N    1 
ATOM   315   C  CA   . ASP A 1 44  ? 42.068  14.679  44.235  1.00 82.50  ? 251 ASP A CA   1 
ATOM   316   C  C    . ASP A 1 44  ? 40.556  14.657  44.080  1.00 88.02  ? 251 ASP A C    1 
ATOM   317   O  O    . ASP A 1 44  ? 40.047  14.348  42.996  1.00 88.71  ? 251 ASP A O    1 
ATOM   318   N  N    . SER A 1 45  ? 39.842  14.973  45.164  1.00 90.02  ? 252 SER A N    1 
ATOM   319   C  CA   . SER A 1 45  ? 38.382  14.928  45.159  1.00 92.28  ? 252 SER A CA   1 
ATOM   320   C  C    . SER A 1 45  ? 37.815  15.715  43.981  1.00 94.31  ? 252 SER A C    1 
ATOM   321   O  O    . SER A 1 45  ? 38.378  16.730  43.553  1.00 100.02 ? 252 SER A O    1 
ATOM   322   N  N    . SER A 1 46  ? 36.702  15.212  43.438  1.00 87.49  ? 253 SER A N    1 
ATOM   323   C  CA   . SER A 1 46  ? 35.985  15.845  42.324  1.00 92.36  ? 253 SER A CA   1 
ATOM   324   C  C    . SER A 1 46  ? 36.915  16.265  41.184  1.00 89.05  ? 253 SER A C    1 
ATOM   325   O  O    . SER A 1 46  ? 36.616  17.189  40.421  1.00 89.39  ? 253 SER A O    1 
ATOM   326   C  CB   . SER A 1 46  ? 35.149  17.031  42.808  1.00 95.75  ? 253 SER A CB   1 
ATOM   327   O  OG   . SER A 1 46  ? 34.537  16.726  44.050  1.00 101.41 ? 253 SER A OG   1 
ATOM   328   N  N    . LYS A 1 47  ? 38.054  15.592  41.060  1.00 83.83  ? 254 LYS A N    1 
ATOM   329   C  CA   . LYS A 1 47  ? 38.813  15.601  39.824  1.00 84.16  ? 254 LYS A CA   1 
ATOM   330   C  C    . LYS A 1 47  ? 39.022  14.201  39.268  1.00 79.77  ? 254 LYS A C    1 
ATOM   331   O  O    . LYS A 1 47  ? 39.453  14.070  38.115  1.00 83.85  ? 254 LYS A O    1 
ATOM   332   C  CB   . LYS A 1 47  ? 40.173  16.295  40.018  1.00 82.54  ? 254 LYS A CB   1 
ATOM   333   N  N    . SER A 1 48  ? 38.667  13.161  40.024  1.00 72.15  ? 255 SER A N    1 
ATOM   334   C  CA   . SER A 1 48  ? 38.947  11.768  39.685  1.00 73.40  ? 255 SER A CA   1 
ATOM   335   C  C    . SER A 1 48  ? 37.676  11.103  39.155  1.00 67.47  ? 255 SER A C    1 
ATOM   336   O  O    . SER A 1 48  ? 36.710  10.912  39.902  1.00 66.55  ? 255 SER A O    1 
ATOM   337   C  CB   . SER A 1 48  ? 39.494  11.040  40.920  1.00 71.45  ? 255 SER A CB   1 
ATOM   338   O  OG   . SER A 1 48  ? 39.150  9.674   40.943  1.00 67.17  ? 255 SER A OG   1 
ATOM   339   N  N    . VAL A 1 49  ? 37.669  10.747  37.869  1.00 64.48  ? 256 VAL A N    1 
ATOM   340   C  CA   . VAL A 1 49  ? 36.561  9.959   37.324  1.00 65.20  ? 256 VAL A CA   1 
ATOM   341   C  C    . VAL A 1 49  ? 36.404  8.635   38.068  1.00 66.08  ? 256 VAL A C    1 
ATOM   342   O  O    . VAL A 1 49  ? 35.259  8.253   38.367  1.00 63.27  ? 256 VAL A O    1 
ATOM   343   C  CB   . VAL A 1 49  ? 36.713  9.793   35.811  1.00 62.51  ? 256 VAL A CB   1 
ATOM   344   C  CG1  . VAL A 1 49  ? 35.675  8.837   35.256  1.00 55.06  ? 256 VAL A CG1  1 
ATOM   345   C  CG2  . VAL A 1 49  ? 36.594  11.125  35.131  1.00 63.73  ? 256 VAL A CG2  1 
ATOM   346   N  N    . PRO A 1 50  ? 37.476  7.901   38.422  1.00 67.21  ? 257 PRO A N    1 
ATOM   347   C  CA   . PRO A 1 50  ? 37.268  6.698   39.256  1.00 58.90  ? 257 PRO A CA   1 
ATOM   348   C  C    . PRO A 1 50  ? 36.608  6.991   40.589  1.00 62.06  ? 257 PRO A C    1 
ATOM   349   O  O    . PRO A 1 50  ? 35.674  6.277   40.978  1.00 65.78  ? 257 PRO A O    1 
ATOM   350   C  CB   . PRO A 1 50  ? 38.685  6.143   39.412  1.00 59.87  ? 257 PRO A CB   1 
ATOM   351   C  CG   . PRO A 1 50  ? 39.349  6.533   38.131  1.00 64.14  ? 257 PRO A CG   1 
ATOM   352   C  CD   . PRO A 1 50  ? 38.855  7.940   37.892  1.00 62.47  ? 257 PRO A CD   1 
ATOM   353   N  N    . LEU A 1 51  ? 37.050  8.028   41.304  1.00 65.37  ? 258 LEU A N    1 
ATOM   354   C  CA   . LEU A 1 51  ? 36.410  8.347   42.576  1.00 63.58  ? 258 LEU A CA   1 
ATOM   355   C  C    . LEU A 1 51  ? 34.948  8.703   42.369  1.00 64.38  ? 258 LEU A C    1 
ATOM   356   O  O    . LEU A 1 51  ? 34.090  8.347   43.188  1.00 64.53  ? 258 LEU A O    1 
ATOM   357   C  CB   . LEU A 1 51  ? 37.141  9.488   43.288  1.00 62.84  ? 258 LEU A CB   1 
ATOM   358   N  N    . ALA A 1 52  ? 34.631  9.383   41.269  1.00 63.96  ? 259 ALA A N    1 
ATOM   359   C  CA   . ALA A 1 52  ? 33.231  9.708   41.019  1.00 59.71  ? 259 ALA A CA   1 
ATOM   360   C  C    . ALA A 1 52  ? 32.437  8.448   40.715  1.00 62.34  ? 259 ALA A C    1 
ATOM   361   O  O    . ALA A 1 52  ? 31.290  8.301   41.158  1.00 57.57  ? 259 ALA A O    1 
ATOM   362   C  CB   . ALA A 1 52  ? 33.126  10.717  39.881  1.00 59.37  ? 259 ALA A CB   1 
ATOM   363   N  N    . LEU A 1 53  ? 33.061  7.518   40.000  1.00 66.09  ? 260 LEU A N    1 
ATOM   364   C  CA   . LEU A 1 53  ? 32.379  6.253   39.635  1.00 61.73  ? 260 LEU A CA   1 
ATOM   365   C  C    . LEU A 1 53  ? 32.167  5.407   40.888  1.00 61.13  ? 260 LEU A C    1 
ATOM   366   O  O    . LEU A 1 53  ? 31.109  4.798   40.980  1.00 60.79  ? 260 LEU A O    1 
ATOM   367   C  CB   . LEU A 1 53  ? 33.213  5.511   38.587  1.00 59.36  ? 260 LEU A CB   1 
ATOM   368   C  CG   . LEU A 1 53  ? 32.404  4.846   37.481  1.00 60.90  ? 260 LEU A CG   1 
ATOM   369   C  CD1  . LEU A 1 53  ? 31.435  5.837   36.864  1.00 59.14  ? 260 LEU A CD1  1 
ATOM   370   C  CD2  . LEU A 1 53  ? 33.320  4.266   36.422  1.00 53.90  ? 260 LEU A CD2  1 
ATOM   371   N  N    . GLN A 1 54  ? 33.130  5.387   41.810  1.00 57.64  ? 261 GLN A N    1 
ATOM   372   C  CA   . GLN A 1 54  ? 32.923  4.657   43.079  1.00 64.12  ? 261 GLN A CA   1 
ATOM   373   C  C    . GLN A 1 54  ? 31.782  5.305   43.857  1.00 55.25  ? 261 GLN A C    1 
ATOM   374   O  O    . GLN A 1 54  ? 30.975  4.566   44.390  1.00 56.85  ? 261 GLN A O    1 
ATOM   375   C  CB   . GLN A 1 54  ? 34.196  4.670   43.912  1.00 64.00  ? 261 GLN A CB   1 
ATOM   376   C  CG   . GLN A 1 54  ? 35.322  3.842   43.333  1.00 61.38  ? 261 GLN A CG   1 
ATOM   377   C  CD   . GLN A 1 54  ? 36.612  4.184   44.030  1.00 64.54  ? 261 GLN A CD   1 
ATOM   378   O  OE1  . GLN A 1 54  ? 36.798  5.302   44.493  1.00 61.88  ? 261 GLN A OE1  1 
ATOM   379   N  NE2  . GLN A 1 54  ? 37.501  3.213   44.131  1.00 60.59  ? 261 GLN A NE2  1 
ATOM   380   N  N    . ARG A 1 55  ? 31.731  6.635   43.895  1.00 57.66  ? 262 ARG A N    1 
ATOM   381   C  CA   . ARG A 1 55  ? 30.672  7.328   44.630  1.00 58.74  ? 262 ARG A CA   1 
ATOM   382   C  C    . ARG A 1 55  ? 29.299  6.997   44.057  1.00 63.25  ? 262 ARG A C    1 
ATOM   383   O  O    . ARG A 1 55  ? 28.376  6.642   44.802  1.00 60.70  ? 262 ARG A O    1 
ATOM   384   C  CB   . ARG A 1 55  ? 30.898  8.837   44.622  1.00 54.54  ? 262 ARG A CB   1 
ATOM   385   C  CG   . ARG A 1 55  ? 29.759  9.631   45.264  1.00 52.83  ? 262 ARG A CG   1 
ATOM   386   N  N    . VAL A 1 56  ? 29.141  7.095   42.731  1.00 57.49  ? 263 VAL A N    1 
ATOM   387   C  CA   . VAL A 1 56  ? 27.847  6.757   42.149  1.00 59.13  ? 263 VAL A CA   1 
ATOM   388   C  C    . VAL A 1 56  ? 27.528  5.284   42.377  1.00 60.56  ? 263 VAL A C    1 
ATOM   389   O  O    . VAL A 1 56  ? 26.398  4.929   42.727  1.00 57.01  ? 263 VAL A O    1 
ATOM   390   C  CB   . VAL A 1 56  ? 27.792  7.118   40.655  1.00 57.07  ? 263 VAL A CB   1 
ATOM   391   C  CG1  . VAL A 1 56  ? 26.529  6.525   40.037  1.00 55.64  ? 263 VAL A CG1  1 
ATOM   392   C  CG2  . VAL A 1 56  ? 27.826  8.627   40.466  1.00 48.37  ? 263 VAL A CG2  1 
ATOM   393   N  N    . PHE A 1 57  ? 28.513  4.403   42.201  1.00 57.74  ? 264 PHE A N    1 
ATOM   394   C  CA   . PHE A 1 57  ? 28.233  2.982   42.373  1.00 60.39  ? 264 PHE A CA   1 
ATOM   395   C  C    . PHE A 1 57  ? 27.869  2.677   43.821  1.00 62.99  ? 264 PHE A C    1 
ATOM   396   O  O    . PHE A 1 57  ? 26.855  2.017   44.085  1.00 62.44  ? 264 PHE A O    1 
ATOM   397   C  CB   . PHE A 1 57  ? 29.427  2.138   41.925  1.00 63.37  ? 264 PHE A CB   1 
ATOM   398   C  CG   . PHE A 1 57  ? 29.564  2.005   40.430  1.00 61.74  ? 264 PHE A CG   1 
ATOM   399   C  CD1  . PHE A 1 57  ? 28.544  2.416   39.583  1.00 59.27  ? 264 PHE A CD1  1 
ATOM   400   C  CD2  . PHE A 1 57  ? 30.724  1.456   39.872  1.00 58.90  ? 264 PHE A CD2  1 
ATOM   401   C  CE1  . PHE A 1 57  ? 28.669  2.281   38.201  1.00 58.81  ? 264 PHE A CE1  1 
ATOM   402   C  CE2  . PHE A 1 57  ? 30.863  1.320   38.502  1.00 55.12  ? 264 PHE A CE2  1 
ATOM   403   C  CZ   . PHE A 1 57  ? 29.828  1.736   37.657  1.00 60.46  ? 264 PHE A CZ   1 
ATOM   404   N  N    . TYR A 1 58  ? 28.673  3.172   44.777  1.00 61.78  ? 265 TYR A N    1 
ATOM   405   C  CA   . TYR A 1 58  ? 28.336  3.031   46.198  1.00 61.54  ? 265 TYR A CA   1 
ATOM   406   C  C    . TYR A 1 58  ? 26.912  3.492   46.499  1.00 60.17  ? 265 TYR A C    1 
ATOM   407   O  O    . TYR A 1 58  ? 26.193  2.861   47.282  1.00 64.22  ? 265 TYR A O    1 
ATOM   408   C  CB   . TYR A 1 58  ? 29.316  3.829   47.070  1.00 65.62  ? 265 TYR A CB   1 
ATOM   409   C  CG   . TYR A 1 58  ? 29.005  3.738   48.553  1.00 62.67  ? 265 TYR A CG   1 
ATOM   410   C  CD1  . TYR A 1 58  ? 28.106  4.605   49.152  1.00 65.93  ? 265 TYR A CD1  1 
ATOM   411   C  CD2  . TYR A 1 58  ? 29.591  2.771   49.339  1.00 61.60  ? 265 TYR A CD2  1 
ATOM   412   C  CE1  . TYR A 1 58  ? 27.803  4.497   50.490  1.00 73.64  ? 265 TYR A CE1  1 
ATOM   413   C  CE2  . TYR A 1 58  ? 29.300  2.662   50.676  1.00 64.33  ? 265 TYR A CE2  1 
ATOM   414   C  CZ   . TYR A 1 58  ? 28.409  3.528   51.248  1.00 70.58  ? 265 TYR A CZ   1 
ATOM   415   O  OH   . TYR A 1 58  ? 28.107  3.426   52.584  1.00 77.26  ? 265 TYR A OH   1 
ATOM   416   N  N    . GLU A 1 59  ? 26.494  4.601   45.904  1.00 59.59  ? 266 GLU A N    1 
ATOM   417   C  CA   . GLU A 1 59  ? 25.222  5.186   46.299  1.00 63.48  ? 266 GLU A CA   1 
ATOM   418   C  C    . GLU A 1 59  ? 24.041  4.422   45.711  1.00 70.65  ? 266 GLU A C    1 
ATOM   419   O  O    . GLU A 1 59  ? 23.061  4.155   46.415  1.00 74.03  ? 266 GLU A O    1 
ATOM   420   C  CB   . GLU A 1 59  ? 25.196  6.656   45.907  1.00 63.50  ? 266 GLU A CB   1 
ATOM   421   C  CG   . GLU A 1 59  ? 26.066  7.502   46.832  1.00 65.46  ? 266 GLU A CG   1 
ATOM   422   C  CD   . GLU A 1 59  ? 25.479  8.871   47.072  1.00 83.07  ? 266 GLU A CD   1 
ATOM   423   O  OE1  . GLU A 1 59  ? 25.800  9.787   46.273  1.00 81.54  ? 266 GLU A OE1  1 
ATOM   424   O  OE2  . GLU A 1 59  ? 24.688  9.019   48.043  1.00 80.45  ? 266 GLU A OE2  1 
ATOM   425   N  N    . LEU A 1 60  ? 24.168  3.989   44.463  1.00 67.69  ? 267 LEU A N    1 
ATOM   426   C  CA   . LEU A 1 60  ? 23.114  3.159   43.846  1.00 64.28  ? 267 LEU A CA   1 
ATOM   427   C  C    . LEU A 1 60  ? 22.999  1.839   44.608  1.00 64.48  ? 267 LEU A C    1 
ATOM   428   O  O    . LEU A 1 60  ? 21.948  1.203   44.537  1.00 65.39  ? 267 LEU A O    1 
ATOM   429   C  CB   . LEU A 1 60  ? 23.502  2.907   42.392  1.00 59.72  ? 267 LEU A CB   1 
ATOM   430   C  CG   . LEU A 1 60  ? 23.174  4.013   41.398  1.00 62.70  ? 267 LEU A CG   1 
ATOM   431   C  CD1  . LEU A 1 60  ? 23.933  3.780   40.106  1.00 60.69  ? 267 LEU A CD1  1 
ATOM   432   C  CD2  . LEU A 1 60  ? 21.683  4.051   41.132  1.00 58.53  ? 267 LEU A CD2  1 
ATOM   433   N  N    . GLN A 1 61  ? 24.064  1.431   45.283  1.00 62.19  ? 268 GLN A N    1 
ATOM   434   C  CA   . GLN A 1 61  ? 24.032  0.187   46.037  1.00 64.03  ? 268 GLN A CA   1 
ATOM   435   C  C    . GLN A 1 61  ? 23.504  0.361   47.457  1.00 67.79  ? 268 GLN A C    1 
ATOM   436   O  O    . GLN A 1 61  ? 23.100  -0.631  48.075  1.00 70.17  ? 268 GLN A O    1 
ATOM   437   C  CB   . GLN A 1 61  ? 25.434  -0.428  46.079  1.00 57.95  ? 268 GLN A CB   1 
ATOM   438   C  CG   . GLN A 1 61  ? 25.502  -1.762  46.755  1.00 58.16  ? 268 GLN A CG   1 
ATOM   439   C  CD   . GLN A 1 61  ? 26.832  -2.434  46.566  1.00 60.47  ? 268 GLN A CD   1 
ATOM   440   O  OE1  . GLN A 1 61  ? 27.614  -2.052  45.694  1.00 63.82  ? 268 GLN A OE1  1 
ATOM   441   N  NE2  . GLN A 1 61  ? 27.095  -3.462  47.370  1.00 65.71  ? 268 GLN A NE2  1 
ATOM   442   N  N    . HIS A 1 62  ? 23.506  1.595   47.970  1.00 68.34  ? 269 HIS A N    1 
ATOM   443   C  CA   . HIS A 1 62  ? 23.151  1.824   49.395  1.00 72.41  ? 269 HIS A CA   1 
ATOM   444   C  C    . HIS A 1 62  ? 21.931  2.734   49.580  1.00 72.03  ? 269 HIS A C    1 
ATOM   445   O  O    . HIS A 1 62  ? 21.100  2.392   50.427  1.00 76.85  ? 269 HIS A O    1 
ATOM   446   C  CB   . HIS A 1 62  ? 24.369  2.395   50.122  1.00 69.12  ? 269 HIS A CB   1 
ATOM   447   C  CG   . HIS A 1 62  ? 25.421  1.388   50.420  1.00 69.88  ? 269 HIS A CG   1 
ATOM   448   N  ND1  . HIS A 1 62  ? 26.240  0.867   49.445  1.00 69.27  ? 269 HIS A ND1  1 
ATOM   449   C  CD2  . HIS A 1 62  ? 25.791  0.811   51.578  1.00 73.23  ? 269 HIS A CD2  1 
ATOM   450   C  CE1  . HIS A 1 62  ? 27.065  0.005   49.987  1.00 68.34  ? 269 HIS A CE1  1 
ATOM   451   N  NE2  . HIS A 1 62  ? 26.819  -0.037  51.292  1.00 65.78  ? 269 HIS A NE2  1 
ATOM   452   N  N    . SER A 1 63  ? 21.828  3.847   48.851  1.00 61.73  ? 270 SER A N    1 
ATOM   453   C  CA   . SER A 1 63  ? 20.730  4.783   49.032  1.00 66.29  ? 270 SER A CA   1 
ATOM   454   C  C    . SER A 1 63  ? 19.364  4.115   48.833  1.00 82.01  ? 270 SER A C    1 
ATOM   455   O  O    . SER A 1 63  ? 19.234  3.035   48.233  1.00 74.53  ? 270 SER A O    1 
ATOM   456   C  CB   . SER A 1 63  ? 20.859  5.953   48.062  1.00 65.74  ? 270 SER A CB   1 
ATOM   457   O  OG   . SER A 1 63  ? 19.583  6.439   47.686  1.00 68.11  ? 270 SER A OG   1 
ATOM   458   N  N    . ASP A 1 64  ? 18.335  4.788   49.368  1.00 81.27  ? 271 ASP A N    1 
ATOM   459   C  CA   . ASP A 1 64  ? 16.933  4.461   49.140  1.00 68.74  ? 271 ASP A CA   1 
ATOM   460   C  C    . ASP A 1 64  ? 16.204  5.615   48.470  1.00 69.84  ? 271 ASP A C    1 
ATOM   461   O  O    . ASP A 1 64  ? 14.971  5.593   48.382  1.00 73.28  ? 271 ASP A O    1 
ATOM   462   C  CB   . ASP A 1 64  ? 16.240  4.087   50.457  1.00 68.88  ? 271 ASP A CB   1 
ATOM   463   N  N    . LYS A 1 65  ? 16.937  6.625   48.012  1.00 72.28  ? 272 LYS A N    1 
ATOM   464   C  CA   . LYS A 1 65  ? 16.450  7.741   47.218  1.00 71.08  ? 272 LYS A CA   1 
ATOM   465   C  C    . LYS A 1 65  ? 17.231  7.803   45.908  1.00 71.01  ? 272 LYS A C    1 
ATOM   466   O  O    . LYS A 1 65  ? 18.311  7.210   45.788  1.00 72.99  ? 272 LYS A O    1 
ATOM   467   C  CB   . LYS A 1 65  ? 16.602  9.071   47.977  1.00 73.44  ? 272 LYS A CB   1 
ATOM   468   N  N    . PRO A 1 66  ? 16.701  8.482   44.899  1.00 69.85  ? 273 PRO A N    1 
ATOM   469   C  CA   . PRO A 1 66  ? 17.443  8.630   43.638  1.00 71.18  ? 273 PRO A CA   1 
ATOM   470   C  C    . PRO A 1 66  ? 18.809  9.277   43.834  1.00 71.44  ? 273 PRO A C    1 
ATOM   471   O  O    . PRO A 1 66  ? 18.959  10.241  44.588  1.00 70.28  ? 273 PRO A O    1 
ATOM   472   C  CB   . PRO A 1 66  ? 16.517  9.509   42.794  1.00 70.33  ? 273 PRO A CB   1 
ATOM   473   C  CG   . PRO A 1 66  ? 15.129  9.078   43.269  1.00 70.89  ? 273 PRO A CG   1 
ATOM   474   C  CD   . PRO A 1 66  ? 15.263  8.773   44.744  1.00 64.26  ? 273 PRO A CD   1 
ATOM   475   N  N    . VAL A 1 67  ? 19.812  8.733   43.129  1.00 73.14  ? 274 VAL A N    1 
ATOM   476   C  CA   . VAL A 1 67  ? 21.237  9.146   43.304  1.00 66.34  ? 274 VAL A CA   1 
ATOM   477   C  C    . VAL A 1 67  ? 21.660  10.222  42.305  1.00 65.05  ? 274 VAL A C    1 
ATOM   478   O  O    . VAL A 1 67  ? 21.209  10.181  41.174  1.00 69.37  ? 274 VAL A O    1 
ATOM   479   C  CB   . VAL A 1 67  ? 22.109  7.886   43.171  1.00 68.39  ? 274 VAL A CB   1 
ATOM   480   C  CG1  . VAL A 1 67  ? 23.600  8.164   43.179  1.00 71.10  ? 274 VAL A CG1  1 
ATOM   481   C  CG2  . VAL A 1 67  ? 21.736  6.833   44.197  1.00 64.22  ? 274 VAL A CG2  1 
ATOM   482   N  N    . GLY A 1 68  ? 22.538  11.129  42.725  1.00 68.77  ? 275 GLY A N    1 
ATOM   483   C  CA   . GLY A 1 68  ? 22.991  12.237  41.866  1.00 67.80  ? 275 GLY A CA   1 
ATOM   484   C  C    . GLY A 1 68  ? 24.309  11.969  41.171  1.00 68.68  ? 275 GLY A C    1 
ATOM   485   O  O    . GLY A 1 68  ? 25.061  11.101  41.642  1.00 74.11  ? 275 GLY A O    1 
ATOM   486   N  N    . THR A 1 69  ? 24.597  12.723  40.112  1.00 68.66  ? 276 THR A N    1 
ATOM   487   C  CA   . THR A 1 69  ? 25.794  12.472  39.278  1.00 64.54  ? 276 THR A CA   1 
ATOM   488   C  C    . THR A 1 69  ? 26.547  13.779  39.072  1.00 69.24  ? 276 THR A C    1 
ATOM   489   O  O    . THR A 1 69  ? 27.289  13.889  38.086  1.00 66.04  ? 276 THR A O    1 
ATOM   490   C  CB   . THR A 1 69  ? 25.351  11.906  37.928  1.00 70.46  ? 276 THR A CB   1 
ATOM   491   O  OG1  . THR A 1 69  ? 24.368  12.774  37.365  1.00 67.78  ? 276 THR A OG1  1 
ATOM   492   C  CG2  . THR A 1 69  ? 24.773  10.513  38.032  1.00 68.32  ? 276 THR A CG2  1 
ATOM   493   N  N    . LYS A 1 70  ? 26.363  14.721  39.986  1.00 70.09  ? 277 LYS A N    1 
ATOM   494   C  CA   . LYS A 1 70  ? 26.998  16.052  39.864  1.00 67.94  ? 277 LYS A CA   1 
ATOM   495   C  C    . LYS A 1 70  ? 28.522  15.919  39.908  1.00 69.12  ? 277 LYS A C    1 
ATOM   496   O  O    . LYS A 1 70  ? 29.176  16.478  39.021  1.00 69.35  ? 277 LYS A O    1 
ATOM   497   C  CB   . LYS A 1 70  ? 26.462  16.945  40.981  1.00 69.27  ? 277 LYS A CB   1 
ATOM   498   C  CG   . LYS A 1 70  ? 25.071  16.605  41.495  1.00 68.51  ? 277 LYS A CG   1 
ATOM   499   C  CD   . LYS A 1 70  ? 25.063  16.288  42.970  1.00 65.42  ? 277 LYS A CD   1 
ATOM   500   C  CE   . LYS A 1 70  ? 23.702  15.873  43.475  1.00 54.49  ? 277 LYS A CE   1 
ATOM   501   N  NZ   . LYS A 1 70  ? 23.796  14.676  44.340  1.00 56.73  ? 277 LYS A NZ   1 
ATOM   502   N  N    . LYS A 1 71  ? 29.062  15.219  40.904  1.00 64.62  ? 278 LYS A N    1 
ATOM   503   C  CA   . LYS A 1 71  ? 30.512  15.116  41.028  1.00 65.00  ? 278 LYS A CA   1 
ATOM   504   C  C    . LYS A 1 71  ? 31.130  14.391  39.838  1.00 68.74  ? 278 LYS A C    1 
ATOM   505   O  O    . LYS A 1 71  ? 32.257  14.707  39.435  1.00 65.37  ? 278 LYS A O    1 
ATOM   506   C  CB   . LYS A 1 71  ? 30.875  14.410  42.332  1.00 71.43  ? 278 LYS A CB   1 
ATOM   507   N  N    . LEU A 1 72  ? 30.400  13.440  39.250  1.00 71.90  ? 279 LEU A N    1 
ATOM   508   C  CA   . LEU A 1 72  ? 30.915  12.716  38.089  1.00 68.02  ? 279 LEU A CA   1 
ATOM   509   C  C    . LEU A 1 72  ? 31.050  13.628  36.873  1.00 67.91  ? 279 LEU A C    1 
ATOM   510   O  O    . LEU A 1 72  ? 32.063  13.576  36.162  1.00 67.27  ? 279 LEU A O    1 
ATOM   511   C  CB   . LEU A 1 72  ? 30.011  11.524  37.780  1.00 60.88  ? 279 LEU A CB   1 
ATOM   512   C  CG   . LEU A 1 72  ? 30.324  10.705  36.533  1.00 63.48  ? 279 LEU A CG   1 
ATOM   513   C  CD1  . LEU A 1 72  ? 31.771  10.238  36.548  1.00 62.18  ? 279 LEU A CD1  1 
ATOM   514   C  CD2  . LEU A 1 72  ? 29.355  9.520   36.402  1.00 61.86  ? 279 LEU A CD2  1 
ATOM   515   N  N    . THR A 1 73  ? 30.043  14.466  36.609  1.00 65.38  ? 280 THR A N    1 
ATOM   516   C  CA   . THR A 1 73  ? 30.182  15.412  35.509  1.00 66.47  ? 280 THR A CA   1 
ATOM   517   C  C    . THR A 1 73  ? 31.247  16.455  35.818  1.00 66.86  ? 280 THR A C    1 
ATOM   518   O  O    . THR A 1 73  ? 31.953  16.905  34.906  1.00 65.10  ? 280 THR A O    1 
ATOM   519   C  CB   . THR A 1 73  ? 28.841  16.069  35.203  1.00 63.16  ? 280 THR A CB   1 
ATOM   520   O  OG1  . THR A 1 73  ? 28.150  16.297  36.431  1.00 70.86  ? 280 THR A OG1  1 
ATOM   521   C  CG2  . THR A 1 73  ? 27.990  15.147  34.354  1.00 62.09  ? 280 THR A CG2  1 
ATOM   522   N  N    . LYS A 1 74  ? 31.409  16.819  37.096  1.00 64.52  ? 281 LYS A N    1 
ATOM   523   C  CA   . LYS A 1 74  ? 32.518  17.692  37.473  1.00 65.19  ? 281 LYS A CA   1 
ATOM   524   C  C    . LYS A 1 74  ? 33.849  17.046  37.132  1.00 66.78  ? 281 LYS A C    1 
ATOM   525   O  O    . LYS A 1 74  ? 34.712  17.675  36.512  1.00 75.42  ? 281 LYS A O    1 
ATOM   526   C  CB   . LYS A 1 74  ? 32.460  18.034  38.962  1.00 70.12  ? 281 LYS A CB   1 
ATOM   527   N  N    . SER A 1 75  ? 34.025  15.774  37.497  1.00 66.03  ? 282 SER A N    1 
ATOM   528   C  CA   . SER A 1 75  ? 35.285  15.102  37.194  1.00 67.51  ? 282 SER A CA   1 
ATOM   529   C  C    . SER A 1 75  ? 35.534  14.966  35.697  1.00 63.12  ? 282 SER A C    1 
ATOM   530   O  O    . SER A 1 75  ? 36.681  14.741  35.300  1.00 69.43  ? 282 SER A O    1 
ATOM   531   C  CB   . SER A 1 75  ? 35.338  13.723  37.862  1.00 71.29  ? 282 SER A CB   1 
ATOM   532   O  OG   . SER A 1 75  ? 34.534  12.767  37.177  1.00 69.56  ? 282 SER A OG   1 
ATOM   533   N  N    . PHE A 1 76  ? 34.505  15.091  34.851  1.00 63.41  ? 283 PHE A N    1 
ATOM   534   C  CA   . PHE A 1 76  ? 34.781  15.159  33.415  1.00 68.77  ? 283 PHE A CA   1 
ATOM   535   C  C    . PHE A 1 76  ? 35.471  16.458  33.030  1.00 71.02  ? 283 PHE A C    1 
ATOM   536   O  O    . PHE A 1 76  ? 36.126  16.502  31.988  1.00 72.94  ? 283 PHE A O    1 
ATOM   537   C  CB   . PHE A 1 76  ? 33.509  15.042  32.558  1.00 67.77  ? 283 PHE A CB   1 
ATOM   538   C  CG   . PHE A 1 76  ? 32.820  13.707  32.641  1.00 70.57  ? 283 PHE A CG   1 
ATOM   539   C  CD1  . PHE A 1 76  ? 33.454  12.604  33.205  1.00 70.04  ? 283 PHE A CD1  1 
ATOM   540   C  CD2  . PHE A 1 76  ? 31.525  13.560  32.163  1.00 68.86  ? 283 PHE A CD2  1 
ATOM   541   C  CE1  . PHE A 1 76  ? 32.813  11.381  33.289  1.00 65.33  ? 283 PHE A CE1  1 
ATOM   542   C  CE2  . PHE A 1 76  ? 30.872  12.344  32.253  1.00 70.52  ? 283 PHE A CE2  1 
ATOM   543   C  CZ   . PHE A 1 76  ? 31.522  11.246  32.813  1.00 68.73  ? 283 PHE A CZ   1 
ATOM   544   N  N    . GLY A 1 77  ? 35.335  17.507  33.835  1.00 70.59  ? 284 GLY A N    1 
ATOM   545   C  CA   . GLY A 1 77  ? 35.746  18.837  33.438  1.00 70.08  ? 284 GLY A CA   1 
ATOM   546   C  C    . GLY A 1 77  ? 34.622  19.727  32.953  1.00 71.35  ? 284 GLY A C    1 
ATOM   547   O  O    . GLY A 1 77  ? 34.888  20.728  32.279  1.00 72.19  ? 284 GLY A O    1 
ATOM   548   N  N    . TRP A 1 78  ? 33.397  19.297  33.224  1.00 72.78  ? 285 TRP A N    1 
ATOM   549   C  CA   . TRP A 1 78  ? 32.235  19.981  32.623  1.00 72.01  ? 285 TRP A CA   1 
ATOM   550   C  C    . TRP A 1 78  ? 31.640  21.067  33.502  1.00 74.08  ? 285 TRP A C    1 
ATOM   551   O  O    . TRP A 1 78  ? 31.615  20.907  34.731  1.00 70.70  ? 285 TRP A O    1 
ATOM   552   C  CB   . TRP A 1 78  ? 31.163  18.936  32.317  1.00 69.82  ? 285 TRP A CB   1 
ATOM   553   C  CG   . TRP A 1 78  ? 31.462  18.007  31.188  1.00 70.62  ? 285 TRP A CG   1 
ATOM   554   C  CD1  . TRP A 1 78  ? 32.587  17.945  30.420  1.00 68.46  ? 285 TRP A CD1  1 
ATOM   555   C  CD2  . TRP A 1 78  ? 30.581  16.989  30.696  1.00 70.51  ? 285 TRP A CD2  1 
ATOM   556   N  NE1  . TRP A 1 78  ? 32.465  16.955  29.484  1.00 76.13  ? 285 TRP A NE1  1 
ATOM   557   C  CE2  . TRP A 1 78  ? 31.243  16.355  29.627  1.00 73.52  ? 285 TRP A CE2  1 
ATOM   558   C  CE3  . TRP A 1 78  ? 29.300  16.564  31.053  1.00 70.67  ? 285 TRP A CE3  1 
ATOM   559   C  CZ2  . TRP A 1 78  ? 30.661  15.309  28.915  1.00 75.11  ? 285 TRP A CZ2  1 
ATOM   560   C  CZ3  . TRP A 1 78  ? 28.727  15.531  30.351  1.00 66.93  ? 285 TRP A CZ3  1 
ATOM   561   C  CH2  . TRP A 1 78  ? 29.400  14.914  29.297  1.00 69.99  ? 285 TRP A CH2  1 
ATOM   562   N  N    . GLU A 1 79  ? 31.153  22.121  32.858  1.00 73.97  ? 286 GLU A N    1 
ATOM   563   C  CA   . GLU A 1 79  ? 30.409  23.161  33.596  1.00 75.96  ? 286 GLU A CA   1 
ATOM   564   C  C    . GLU A 1 79  ? 28.944  22.701  33.644  1.00 78.83  ? 286 GLU A C    1 
ATOM   565   O  O    . GLU A 1 79  ? 28.620  21.674  33.013  1.00 73.76  ? 286 GLU A O    1 
ATOM   566   C  CB   . GLU A 1 79  ? 30.611  24.501  32.892  1.00 68.48  ? 286 GLU A CB   1 
ATOM   567   N  N    . THR A 1 80  ? 28.081  23.418  34.361  1.00 80.19  ? 287 THR A N    1 
ATOM   568   C  CA   . THR A 1 80  ? 26.681  22.935  34.510  1.00 78.30  ? 287 THR A CA   1 
ATOM   569   C  C    . THR A 1 80  ? 25.993  22.930  33.139  1.00 82.06  ? 287 THR A C    1 
ATOM   570   O  O    . THR A 1 80  ? 25.204  22.010  32.915  1.00 80.91  ? 287 THR A O    1 
ATOM   571   C  CB   . THR A 1 80  ? 25.925  23.703  35.603  1.00 79.83  ? 287 THR A CB   1 
ATOM   572   O  OG1  . THR A 1 80  ? 26.781  23.836  36.737  1.00 85.41  ? 287 THR A OG1  1 
ATOM   573   C  CG2  . THR A 1 80  ? 24.650  23.018  36.041  1.00 72.27  ? 287 THR A CG2  1 
ATOM   574   N  N    . LEU A 1 81  ? 26.308  23.877  32.247  1.00 78.44  ? 288 LEU A N    1 
ATOM   575   C  CA   . LEU A 1 81  ? 25.600  23.926  30.971  1.00 80.05  ? 288 LEU A CA   1 
ATOM   576   C  C    . LEU A 1 81  ? 25.684  22.593  30.225  1.00 80.96  ? 288 LEU A C    1 
ATOM   577   O  O    . LEU A 1 81  ? 24.711  22.179  29.577  1.00 75.13  ? 288 LEU A O    1 
ATOM   578   N  N    . ASP A 1 82  ? 26.826  21.896  30.333  1.00 77.82  ? 289 ASP A N    1 
ATOM   579   C  CA   . ASP A 1 82  ? 27.022  20.633  29.629  1.00 71.90  ? 289 ASP A CA   1 
ATOM   580   C  C    . ASP A 1 82  ? 26.066  19.541  30.091  1.00 70.17  ? 289 ASP A C    1 
ATOM   581   O  O    . ASP A 1 82  ? 25.826  18.596  29.335  1.00 78.12  ? 289 ASP A O    1 
ATOM   582   C  CB   . ASP A 1 82  ? 28.460  20.153  29.803  1.00 69.93  ? 289 ASP A CB   1 
ATOM   583   C  CG   . ASP A 1 82  ? 29.477  21.178  29.348  1.00 69.66  ? 289 ASP A CG   1 
ATOM   584   O  OD1  . ASP A 1 82  ? 29.609  21.411  28.123  1.00 69.72  ? 289 ASP A OD1  1 
ATOM   585   O  OD2  . ASP A 1 82  ? 30.152  21.750  30.222  1.00 64.82  ? 289 ASP A OD2  1 
ATOM   586   N  N    . SER A 1 83  ? 25.549  19.648  31.309  1.00 71.59  ? 290 SER A N    1 
ATOM   587   C  CA   . SER A 1 83  ? 24.586  18.646  31.829  1.00 70.70  ? 290 SER A CA   1 
ATOM   588   C  C    . SER A 1 83  ? 23.214  18.858  31.177  1.00 72.42  ? 290 SER A C    1 
ATOM   589   O  O    . SER A 1 83  ? 22.264  18.172  31.575  1.00 64.46  ? 290 SER A O    1 
ATOM   590   C  CB   . SER A 1 83  ? 24.509  18.697  33.333  1.00 68.97  ? 290 SER A CB   1 
ATOM   591   O  OG   . SER A 1 83  ? 25.461  17.828  33.922  1.00 68.87  ? 290 SER A OG   1 
ATOM   592   N  N    . PHE A 1 84  ? 23.128  19.777  30.214  1.00 68.34  ? 291 PHE A N    1 
ATOM   593   C  CA   . PHE A 1 84  ? 21.842  20.069  29.533  1.00 68.92  ? 291 PHE A CA   1 
ATOM   594   C  C    . PHE A 1 84  ? 22.022  19.872  28.024  1.00 71.79  ? 291 PHE A C    1 
ATOM   595   O  O    . PHE A 1 84  ? 21.062  20.128  27.285  1.00 72.11  ? 291 PHE A O    1 
ATOM   596   C  CB   . PHE A 1 84  ? 21.313  21.446  29.942  1.00 70.97  ? 291 PHE A CB   1 
ATOM   597   C  CG   . PHE A 1 84  ? 20.984  21.586  31.406  1.00 74.04  ? 291 PHE A CG   1 
ATOM   598   C  CD1  . PHE A 1 84  ? 21.954  21.958  32.322  1.00 70.85  ? 291 PHE A CD1  1 
ATOM   599   C  CD2  . PHE A 1 84  ? 19.704  21.344  31.872  1.00 78.11  ? 291 PHE A CD2  1 
ATOM   600   C  CE1  . PHE A 1 84  ? 21.656  22.071  33.669  1.00 67.48  ? 291 PHE A CE1  1 
ATOM   601   C  CE2  . PHE A 1 84  ? 19.402  21.471  33.218  1.00 72.73  ? 291 PHE A CE2  1 
ATOM   602   C  CZ   . PHE A 1 84  ? 20.379  21.833  34.115  1.00 71.60  ? 291 PHE A CZ   1 
ATOM   603   N  N    . MET A 1 85  ? 23.203  19.433  27.582  1.00 71.68  ? 292 MET A N    1 
ATOM   604   C  CA   . MET A 1 85  ? 23.395  19.075  26.153  1.00 69.28  ? 292 MET A CA   1 
ATOM   605   C  C    . MET A 1 85  ? 23.159  17.573  26.031  1.00 64.60  ? 292 MET A C    1 
ATOM   606   O  O    . MET A 1 85  ? 23.722  16.817  26.833  1.00 67.24  ? 292 MET A O    1 
ATOM   607   C  CB   . MET A 1 85  ? 24.800  19.401  25.650  1.00 70.50  ? 292 MET A CB   1 
ATOM   608   C  CG   . MET A 1 85  ? 25.083  18.868  24.258  1.00 70.59  ? 292 MET A CG   1 
ATOM   609   S  SD   . MET A 1 85  ? 26.677  19.396  23.598  1.00 86.81  ? 292 MET A SD   1 
ATOM   610   C  CE   . MET A 1 85  ? 26.263  19.582  21.866  1.00 68.43  ? 292 MET A CE   1 
ATOM   611   N  N    . GLN A 1 86  ? 22.315  17.182  25.086  1.00 63.57  ? 293 GLN A N    1 
ATOM   612   C  CA   . GLN A 1 86  ? 21.940  15.759  24.926  1.00 61.62  ? 293 GLN A CA   1 
ATOM   613   C  C    . GLN A 1 86  ? 23.071  15.011  24.230  1.00 63.23  ? 293 GLN A C    1 
ATOM   614   O  O    . GLN A 1 86  ? 23.731  15.606  23.366  1.00 60.15  ? 293 GLN A O    1 
ATOM   615   C  CB   . GLN A 1 86  ? 20.610  15.699  24.180  1.00 59.94  ? 293 GLN A CB   1 
ATOM   616   C  CG   . GLN A 1 86  ? 19.529  16.556  24.817  1.00 63.13  ? 293 GLN A CG   1 
ATOM   617   C  CD   . GLN A 1 86  ? 18.147  16.224  24.316  1.00 65.90  ? 293 GLN A CD   1 
ATOM   618   O  OE1  . GLN A 1 86  ? 17.897  15.146  23.791  1.00 66.04  ? 293 GLN A OE1  1 
ATOM   619   N  NE2  . GLN A 1 86  ? 17.231  17.163  24.476  1.00 61.07  ? 293 GLN A NE2  1 
ATOM   620   N  N    . HIS A 1 87  ? 23.245  13.738  24.563  1.00 60.14  ? 294 HIS A N    1 
ATOM   621   C  CA   . HIS A 1 87  ? 24.377  12.995  24.053  1.00 54.88  ? 294 HIS A CA   1 
ATOM   622   C  C    . HIS A 1 87  ? 23.983  11.569  23.688  1.00 57.58  ? 294 HIS A C    1 
ATOM   623   O  O    . HIS A 1 87  ? 22.887  11.087  24.000  1.00 52.21  ? 294 HIS A O    1 
ATOM   624   C  CB   . HIS A 1 87  ? 25.523  13.036  25.065  1.00 54.95  ? 294 HIS A CB   1 
ATOM   625   C  CG   . HIS A 1 87  ? 26.426  14.215  24.875  1.00 61.24  ? 294 HIS A CG   1 
ATOM   626   N  ND1  . HIS A 1 87  ? 26.709  15.113  25.883  1.00 63.15  ? 294 HIS A ND1  1 
ATOM   627   C  CD2  . HIS A 1 87  ? 27.088  14.655  23.780  1.00 57.03  ? 294 HIS A CD2  1 
ATOM   628   C  CE1  . HIS A 1 87  ? 27.511  16.054  25.416  1.00 63.61  ? 294 HIS A CE1  1 
ATOM   629   N  NE2  . HIS A 1 87  ? 27.756  15.800  24.143  1.00 59.87  ? 294 HIS A NE2  1 
ATOM   630   N  N    . ASP A 1 88  ? 24.919  10.913  22.996  1.00 56.80  ? 295 ASP A N    1 
ATOM   631   C  CA   . ASP A 1 88  ? 24.805  9.546   22.516  1.00 42.94  ? 295 ASP A CA   1 
ATOM   632   C  C    . ASP A 1 88  ? 25.398  8.606   23.564  1.00 48.15  ? 295 ASP A C    1 
ATOM   633   O  O    . ASP A 1 88  ? 26.515  8.828   24.028  1.00 46.26  ? 295 ASP A O    1 
ATOM   634   C  CB   . ASP A 1 88  ? 25.558  9.456   21.187  1.00 47.96  ? 295 ASP A CB   1 
ATOM   635   C  CG   . ASP A 1 88  ? 25.558  8.063   20.574  1.00 47.02  ? 295 ASP A CG   1 
ATOM   636   O  OD1  . ASP A 1 88  ? 26.171  7.134   21.160  1.00 45.50  ? 295 ASP A OD1  1 
ATOM   637   O  OD2  . ASP A 1 88  ? 24.991  7.932   19.459  1.00 46.87  ? 295 ASP A OD2  1 
ATOM   638   N  N    . VAL A 1 89  ? 24.651  7.562   23.943  1.00 43.67  ? 296 VAL A N    1 
ATOM   639   C  CA   . VAL A 1 89  ? 25.105  6.722   25.047  1.00 49.83  ? 296 VAL A CA   1 
ATOM   640   C  C    . VAL A 1 89  ? 26.314  5.894   24.635  1.00 49.77  ? 296 VAL A C    1 
ATOM   641   O  O    . VAL A 1 89  ? 27.174  5.583   25.471  1.00 49.87  ? 296 VAL A O    1 
ATOM   642   C  CB   . VAL A 1 89  ? 23.975  5.817   25.593  1.00 51.12  ? 296 VAL A CB   1 
ATOM   643   C  CG1  . VAL A 1 89  ? 23.529  4.753   24.559  1.00 42.15  ? 296 VAL A CG1  1 
ATOM   644   C  CG2  . VAL A 1 89  ? 24.442  5.138   26.854  1.00 48.41  ? 296 VAL A CG2  1 
ATOM   645   N  N    . GLN A 1 90  ? 26.437  5.532   23.365  1.00 47.58  ? 297 GLN A N    1 
ATOM   646   C  CA   . GLN A 1 90  ? 27.574  4.660   22.988  1.00 49.22  ? 297 GLN A CA   1 
ATOM   647   C  C    . GLN A 1 90  ? 28.824  5.535   22.889  1.00 52.94  ? 297 GLN A C    1 
ATOM   648   O  O    . GLN A 1 90  ? 29.911  5.041   23.192  1.00 49.78  ? 297 GLN A O    1 
ATOM   649   C  CB   . GLN A 1 90  ? 27.273  3.871   21.713  1.00 45.78  ? 297 GLN A CB   1 
ATOM   650   C  CG   . GLN A 1 90  ? 28.369  2.896   21.322  1.00 42.26  ? 297 GLN A CG   1 
ATOM   651   C  CD   . GLN A 1 90  ? 29.206  3.516   20.236  1.00 41.13  ? 297 GLN A CD   1 
ATOM   652   O  OE1  . GLN A 1 90  ? 28.788  4.469   19.600  1.00 49.86  ? 297 GLN A OE1  1 
ATOM   653   N  NE2  . GLN A 1 90  ? 30.383  2.976   19.996  1.00 44.10  ? 297 GLN A NE2  1 
ATOM   654   N  N    . GLU A 1 91  ? 28.660  6.799   22.510  1.00 51.66  ? 298 GLU A N    1 
ATOM   655   C  CA   . GLU A 1 91  ? 29.834  7.671   22.487  1.00 48.27  ? 298 GLU A CA   1 
ATOM   656   C  C    . GLU A 1 91  ? 30.379  7.872   23.890  1.00 46.98  ? 298 GLU A C    1 
ATOM   657   O  O    . GLU A 1 91  ? 31.599  7.840   24.105  1.00 48.48  ? 298 GLU A O    1 
ATOM   658   C  CB   . GLU A 1 91  ? 29.494  9.023   21.838  1.00 44.64  ? 298 GLU A CB   1 
ATOM   659   C  CG   . GLU A 1 91  ? 30.673  10.007  21.843  1.00 49.90  ? 298 GLU A CG   1 
ATOM   660   C  CD   . GLU A 1 91  ? 30.421  11.271  21.023  1.00 48.90  ? 298 GLU A CD   1 
ATOM   661   O  OE1  . GLU A 1 91  ? 31.392  11.958  20.663  1.00 51.36  ? 298 GLU A OE1  1 
ATOM   662   O  OE2  . GLU A 1 91  ? 29.254  11.583  20.711  1.00 58.13  ? 298 GLU A OE2  1 
ATOM   663   N  N    . LEU A 1 92  ? 29.492  8.083   24.861  1.00 46.73  ? 299 LEU A N    1 
ATOM   664   C  CA   . LEU A 1 92  ? 29.943  8.168   26.242  1.00 47.60  ? 299 LEU A CA   1 
ATOM   665   C  C    . LEU A 1 92  ? 30.621  6.871   26.646  1.00 48.75  ? 299 LEU A C    1 
ATOM   666   O  O    . LEU A 1 92  ? 31.711  6.878   27.226  1.00 51.46  ? 299 LEU A O    1 
ATOM   667   C  CB   . LEU A 1 92  ? 28.766  8.472   27.171  1.00 46.70  ? 299 LEU A CB   1 
ATOM   668   C  CG   . LEU A 1 92  ? 29.101  8.436   28.670  1.00 50.45  ? 299 LEU A CG   1 
ATOM   669   C  CD1  . LEU A 1 92  ? 30.078  9.558   29.040  1.00 48.82  ? 299 LEU A CD1  1 
ATOM   670   C  CD2  . LEU A 1 92  ? 27.844  8.563   29.513  1.00 53.57  ? 299 LEU A CD2  1 
ATOM   671   N  N    . CYS A 1 93  ? 29.988  5.743   26.326  1.00 46.05  ? 300 CYS A N    1 
ATOM   672   C  CA   . CYS A 1 93  ? 30.516  4.463   26.764  1.00 49.30  ? 300 CYS A CA   1 
ATOM   673   C  C    . CYS A 1 93  ? 31.945  4.283   26.292  1.00 49.94  ? 300 CYS A C    1 
ATOM   674   O  O    . CYS A 1 93  ? 32.800  3.839   27.064  1.00 51.06  ? 300 CYS A O    1 
ATOM   675   C  CB   . CYS A 1 93  ? 29.636  3.326   26.258  1.00 49.86  ? 300 CYS A CB   1 
ATOM   676   S  SG   . CYS A 1 93  ? 30.134  1.697   26.823  1.00 47.14  ? 300 CYS A SG   1 
ATOM   677   N  N    . ARG A 1 94  ? 32.228  4.645   25.029  1.00 51.43  ? 301 ARG A N    1 
ATOM   678   C  CA   . ARG A 1 94  ? 33.576  4.494   24.492  1.00 46.34  ? 301 ARG A CA   1 
ATOM   679   C  C    . ARG A 1 94  ? 34.572  5.327   25.287  1.00 52.41  ? 301 ARG A C    1 
ATOM   680   O  O    . ARG A 1 94  ? 35.647  4.845   25.670  1.00 52.07  ? 301 ARG A O    1 
ATOM   681   C  CB   . ARG A 1 94  ? 33.609  4.889   23.017  1.00 47.79  ? 301 ARG A CB   1 
ATOM   682   C  CG   . ARG A 1 94  ? 32.817  3.968   22.086  1.00 49.99  ? 301 ARG A CG   1 
ATOM   683   C  CD   . ARG A 1 94  ? 33.623  2.734   21.677  1.00 53.07  ? 301 ARG A CD   1 
ATOM   684   N  NE   . ARG A 1 94  ? 34.051  1.907   22.811  1.00 48.55  ? 301 ARG A NE   1 
ATOM   685   C  CZ   . ARG A 1 94  ? 33.260  1.082   23.492  1.00 46.88  ? 301 ARG A CZ   1 
ATOM   686   N  NH1  . ARG A 1 94  ? 31.988  0.937   23.165  1.00 41.26  ? 301 ARG A NH1  1 
ATOM   687   N  NH2  . ARG A 1 94  ? 33.750  0.387   24.510  1.00 48.28  ? 301 ARG A NH2  1 
ATOM   688   N  N    . VAL A 1 95  ? 34.217  6.577   25.563  1.00 48.65  ? 302 VAL A N    1 
ATOM   689   C  CA   . VAL A 1 95  ? 35.127  7.479   26.255  1.00 47.25  ? 302 VAL A CA   1 
ATOM   690   C  C    . VAL A 1 95  ? 35.257  7.105   27.731  1.00 49.86  ? 302 VAL A C    1 
ATOM   691   O  O    . VAL A 1 95  ? 36.356  7.123   28.299  1.00 53.64  ? 302 VAL A O    1 
ATOM   692   C  CB   . VAL A 1 95  ? 34.644  8.925   26.059  1.00 47.22  ? 302 VAL A CB   1 
ATOM   693   C  CG1  . VAL A 1 95  ? 35.549  9.900   26.781  1.00 45.04  ? 302 VAL A CG1  1 
ATOM   694   C  CG2  . VAL A 1 95  ? 34.570  9.243   24.565  1.00 36.42  ? 302 VAL A CG2  1 
ATOM   695   N  N    . LEU A 1 96  ? 34.156  6.750   28.380  1.00 52.41  ? 303 LEU A N    1 
ATOM   696   C  CA   . LEU A 1 96  ? 34.220  6.521   29.819  1.00 50.07  ? 303 LEU A CA   1 
ATOM   697   C  C    . LEU A 1 96  ? 34.968  5.230   30.132  1.00 54.89  ? 303 LEU A C    1 
ATOM   698   O  O    . LEU A 1 96  ? 35.781  5.182   31.064  1.00 61.58  ? 303 LEU A O    1 
ATOM   699   C  CB   . LEU A 1 96  ? 32.806  6.513   30.384  1.00 50.75  ? 303 LEU A CB   1 
ATOM   700   C  CG   . LEU A 1 96  ? 32.436  6.519   31.858  1.00 51.71  ? 303 LEU A CG   1 
ATOM   701   C  CD1  . LEU A 1 96  ? 32.316  5.093   32.320  1.00 57.63  ? 303 LEU A CD1  1 
ATOM   702   C  CD2  . LEU A 1 96  ? 33.440  7.281   32.669  1.00 52.89  ? 303 LEU A CD2  1 
ATOM   703   N  N    . LEU A 1 97  ? 34.735  4.181   29.352  1.00 49.54  ? 304 LEU A N    1 
ATOM   704   C  CA   . LEU A 1 97  ? 35.456  2.936   29.580  1.00 48.18  ? 304 LEU A CA   1 
ATOM   705   C  C    . LEU A 1 97  ? 36.937  3.085   29.244  1.00 54.71  ? 304 LEU A C    1 
ATOM   706   O  O    . LEU A 1 97  ? 37.799  2.490   29.903  1.00 54.80  ? 304 LEU A O    1 
ATOM   707   C  CB   . LEU A 1 97  ? 34.836  1.825   28.745  1.00 45.57  ? 304 LEU A CB   1 
ATOM   708   C  CG   . LEU A 1 97  ? 33.583  1.180   29.286  1.00 46.27  ? 304 LEU A CG   1 
ATOM   709   C  CD1  . LEU A 1 97  ? 33.245  -0.055  28.447  1.00 43.10  ? 304 LEU A CD1  1 
ATOM   710   C  CD2  . LEU A 1 97  ? 33.784  0.821   30.755  1.00 44.99  ? 304 LEU A CD2  1 
ATOM   711   N  N    . ASP A 1 98  ? 37.257  3.850   28.201  1.00 55.84  ? 305 ASP A N    1 
ATOM   712   C  CA   . ASP A 1 98  ? 38.656  4.081   27.879  1.00 53.42  ? 305 ASP A CA   1 
ATOM   713   C  C    . ASP A 1 98  ? 39.358  4.767   29.032  1.00 55.33  ? 305 ASP A C    1 
ATOM   714   O  O    . ASP A 1 98  ? 40.402  4.307   29.505  1.00 59.99  ? 305 ASP A O    1 
ATOM   715   C  CB   . ASP A 1 98  ? 38.784  4.929   26.622  1.00 51.32  ? 305 ASP A CB   1 
ATOM   716   C  CG   . ASP A 1 98  ? 40.224  5.170   26.249  1.00 52.90  ? 305 ASP A CG   1 
ATOM   717   O  OD1  . ASP A 1 98  ? 40.875  4.227   25.767  1.00 50.38  ? 305 ASP A OD1  1 
ATOM   718   O  OD2  . ASP A 1 98  ? 40.722  6.287   26.493  1.00 60.68  ? 305 ASP A OD2  1 
ATOM   719   N  N    . ASN A 1 99  ? 38.791  5.874   29.495  1.00 55.80  ? 306 ASN A N    1 
ATOM   720   C  CA   . ASN A 1 99  ? 39.334  6.593   30.642  1.00 56.18  ? 306 ASN A CA   1 
ATOM   721   C  C    . ASN A 1 99  ? 39.535  5.655   31.831  1.00 52.91  ? 306 ASN A C    1 
ATOM   722   O  O    . ASN A 1 99  ? 40.613  5.614   32.441  1.00 54.56  ? 306 ASN A O    1 
ATOM   723   C  CB   . ASN A 1 99  ? 38.383  7.758   30.954  1.00 53.30  ? 306 ASN A CB   1 
ATOM   724   C  CG   . ASN A 1 99  ? 38.678  8.453   32.263  1.00 60.30  ? 306 ASN A CG   1 
ATOM   725   O  OD1  . ASN A 1 99  ? 38.800  7.821   33.308  1.00 62.20  ? 306 ASN A OD1  1 
ATOM   726   N  ND2  . ASN A 1 99  ? 38.721  9.781   32.224  1.00 62.23  ? 306 ASN A ND2  1 
ATOM   727   N  N    . VAL A 1 100 ? 38.508  4.872   32.159  1.00 51.09  ? 307 VAL A N    1 
ATOM   728   C  CA   . VAL A 1 100 ? 38.619  3.997   33.317  1.00 58.91  ? 307 VAL A CA   1 
ATOM   729   C  C    . VAL A 1 100 ? 39.666  2.924   33.067  1.00 55.26  ? 307 VAL A C    1 
ATOM   730   O  O    . VAL A 1 100 ? 40.430  2.567   33.969  1.00 48.65  ? 307 VAL A O    1 
ATOM   731   C  CB   . VAL A 1 100 ? 37.250  3.397   33.683  1.00 54.88  ? 307 VAL A CB   1 
ATOM   732   C  CG1  . VAL A 1 100 ? 37.399  2.403   34.823  1.00 57.07  ? 307 VAL A CG1  1 
ATOM   733   C  CG2  . VAL A 1 100 ? 36.307  4.495   34.106  1.00 53.26  ? 307 VAL A CG2  1 
ATOM   734   N  N    . GLU A 1 101 ? 39.738  2.407   31.839  1.00 55.45  ? 308 GLU A N    1 
ATOM   735   C  CA   . GLU A 1 101 ? 40.707  1.354   31.559  1.00 50.84  ? 308 GLU A CA   1 
ATOM   736   C  C    . GLU A 1 101 ? 42.125  1.853   31.790  1.00 57.83  ? 308 GLU A C    1 
ATOM   737   O  O    . GLU A 1 101 ? 42.921  1.208   32.483  1.00 57.88  ? 308 GLU A O    1 
ATOM   738   C  CB   . GLU A 1 101 ? 40.549  0.855   30.137  1.00 49.45  ? 308 GLU A CB   1 
ATOM   739   C  CG   . GLU A 1 101 ? 41.469  -0.278  29.825  1.00 52.96  ? 308 GLU A CG   1 
ATOM   740   C  CD   . GLU A 1 101 ? 41.379  -0.703  28.388  1.00 57.71  ? 308 GLU A CD   1 
ATOM   741   O  OE1  . GLU A 1 101 ? 42.349  -1.312  27.887  1.00 67.51  ? 308 GLU A OE1  1 
ATOM   742   O  OE2  . GLU A 1 101 ? 40.336  -0.428  27.757  1.00 58.89  ? 308 GLU A OE2  1 
ATOM   743   N  N    . ASN A 1 102 ? 42.449  3.023   31.235  1.00 56.49  ? 309 ASN A N    1 
ATOM   744   C  CA   . ASN A 1 102 ? 43.769  3.588   31.453  1.00 65.44  ? 309 ASN A CA   1 
ATOM   745   C  C    . ASN A 1 102 ? 44.016  3.826   32.937  1.00 63.28  ? 309 ASN A C    1 
ATOM   746   O  O    . ASN A 1 102 ? 45.094  3.505   33.450  1.00 63.57  ? 309 ASN A O    1 
ATOM   747   C  CB   . ASN A 1 102 ? 43.935  4.875   30.637  1.00 60.70  ? 309 ASN A CB   1 
ATOM   748   C  CG   . ASN A 1 102 ? 43.993  4.601   29.148  1.00 70.83  ? 309 ASN A CG   1 
ATOM   749   O  OD1  . ASN A 1 102 ? 44.321  3.482   28.719  1.00 67.79  ? 309 ASN A OD1  1 
ATOM   750   N  ND2  . ASN A 1 102 ? 43.654  5.612   28.342  1.00 77.12  ? 309 ASN A ND2  1 
ATOM   751   N  N    . LYS A 1 103 ? 43.002  4.293   33.654  1.00 58.60  ? 310 LYS A N    1 
ATOM   752   C  CA   . LYS A 1 103 ? 43.185  4.591   35.097  1.00 59.47  ? 310 LYS A CA   1 
ATOM   753   C  C    . LYS A 1 103 ? 43.326  3.296   35.914  1.00 57.44  ? 310 LYS A C    1 
ATOM   754   O  O    . LYS A 1 103 ? 43.787  3.395   37.052  1.00 62.68  ? 310 LYS A O    1 
ATOM   755   C  CB   . LYS A 1 103 ? 42.056  5.500   35.581  1.00 60.02  ? 310 LYS A CB   1 
ATOM   756   C  CG   . LYS A 1 103 ? 42.217  6.969   35.220  1.00 55.90  ? 310 LYS A CG   1 
ATOM   757   N  N    . MET A 1 104 ? 42.958  2.136   35.365  1.00 59.38  ? 311 MET A N    1 
ATOM   758   C  CA   . MET A 1 104 ? 43.171  0.874   36.071  1.00 58.68  ? 311 MET A CA   1 
ATOM   759   C  C    . MET A 1 104 ? 44.571  0.298   35.854  1.00 63.06  ? 311 MET A C    1 
ATOM   760   O  O    . MET A 1 104 ? 44.942  -0.673  36.527  1.00 61.06  ? 311 MET A O    1 
ATOM   761   C  CB   . MET A 1 104 ? 42.136  -0.178  35.638  1.00 54.56  ? 311 MET A CB   1 
ATOM   762   C  CG   . MET A 1 104 ? 40.708  0.052   36.136  1.00 53.59  ? 311 MET A CG   1 
ATOM   763   S  SD   . MET A 1 104 ? 39.734  -1.463  36.055  1.00 65.15  ? 311 MET A SD   1 
ATOM   764   C  CE   . MET A 1 104 ? 38.362  -1.032  37.100  1.00 51.12  ? 311 MET A CE   1 
ATOM   765   N  N    . LYS A 1 105 ? 45.346  0.849   34.923  1.00 62.02  ? 312 LYS A N    1 
ATOM   766   C  CA   . LYS A 1 105 ? 46.694  0.345   34.683  1.00 65.27  ? 312 LYS A CA   1 
ATOM   767   C  C    . LYS A 1 105 ? 47.578  0.583   35.901  1.00 60.54  ? 312 LYS A C    1 
ATOM   768   O  O    . LYS A 1 105 ? 47.497  1.623   36.556  1.00 59.10  ? 312 LYS A O    1 
ATOM   769   C  CB   . LYS A 1 105 ? 47.300  1.010   33.445  1.00 58.84  ? 312 LYS A CB   1 
ATOM   770   C  CG   . LYS A 1 105 ? 46.570  0.614   32.193  1.00 58.31  ? 312 LYS A CG   1 
ATOM   771   C  CD   . LYS A 1 105 ? 47.238  1.095   30.926  1.00 55.53  ? 312 LYS A CD   1 
ATOM   772   C  CE   . LYS A 1 105 ? 46.398  0.646   29.712  1.00 66.34  ? 312 LYS A CE   1 
ATOM   773   N  NZ   . LYS A 1 105 ? 46.594  1.495   28.479  1.00 68.43  ? 312 LYS A NZ   1 
ATOM   774   N  N    . GLY A 1 106 ? 48.386  -0.406  36.252  1.00 61.00  ? 313 GLY A N    1 
ATOM   775   C  CA   . GLY A 1 106 ? 49.297  -0.263  37.400  1.00 65.12  ? 313 GLY A CA   1 
ATOM   776   C  C    . GLY A 1 106 ? 48.615  -0.517  38.728  1.00 70.46  ? 313 GLY A C    1 
ATOM   777   O  O    . GLY A 1 106 ? 49.232  -0.220  39.757  1.00 74.37  ? 313 GLY A O    1 
ATOM   778   N  N    . THR A 1 107 ? 47.387  -1.033  38.709  1.00 70.07  ? 314 THR A N    1 
ATOM   779   C  CA   . THR A 1 107 ? 46.633  -1.305  39.933  1.00 68.58  ? 314 THR A CA   1 
ATOM   780   C  C    . THR A 1 107 ? 46.330  -2.795  40.033  1.00 68.63  ? 314 THR A C    1 
ATOM   781   O  O    . THR A 1 107 ? 46.637  -3.583  39.128  1.00 68.57  ? 314 THR A O    1 
ATOM   782   C  CB   . THR A 1 107 ? 45.327  -0.517  39.974  1.00 62.68  ? 314 THR A CB   1 
ATOM   783   O  OG1  . THR A 1 107 ? 44.389  -1.120  39.064  1.00 61.74  ? 314 THR A OG1  1 
ATOM   784   C  CG2  . THR A 1 107 ? 45.570  0.932   39.603  1.00 62.61  ? 314 THR A CG2  1 
ATOM   785   N  N    . CYS A 1 108 ? 45.705  -3.173  41.151  1.00 65.40  ? 315 CYS A N    1 
ATOM   786   C  CA   . CYS A 1 108 ? 45.323  -4.564  41.360  1.00 67.09  ? 315 CYS A CA   1 
ATOM   787   C  C    . CYS A 1 108 ? 44.300  -5.029  40.328  1.00 71.67  ? 315 CYS A C    1 
ATOM   788   O  O    . CYS A 1 108 ? 44.151  -6.240  40.109  1.00 69.35  ? 315 CYS A O    1 
ATOM   789   C  CB   . CYS A 1 108 ? 44.774  -4.743  42.784  1.00 73.97  ? 315 CYS A CB   1 
ATOM   790   S  SG   . CYS A 1 108 ? 43.585  -3.461  43.322  1.00 77.73  ? 315 CYS A SG   1 
ATOM   791   N  N    . VAL A 1 109 ? 43.619  -4.097  39.666  1.00 63.71  ? 316 VAL A N    1 
ATOM   792   C  CA   . VAL A 1 109 ? 42.532  -4.453  38.764  1.00 60.83  ? 316 VAL A CA   1 
ATOM   793   C  C    . VAL A 1 109 ? 42.848  -4.051  37.323  1.00 64.42  ? 316 VAL A C    1 
ATOM   794   O  O    . VAL A 1 109 ? 41.941  -3.762  36.535  1.00 60.88  ? 316 VAL A O    1 
ATOM   795   C  CB   . VAL A 1 109 ? 41.212  -3.819  39.245  1.00 60.25  ? 316 VAL A CB   1 
ATOM   796   C  CG1  . VAL A 1 109 ? 40.727  -4.502  40.527  1.00 62.08  ? 316 VAL A CG1  1 
ATOM   797   C  CG2  . VAL A 1 109 ? 41.371  -2.310  39.458  1.00 54.16  ? 316 VAL A CG2  1 
ATOM   798   N  N    . GLU A 1 110 ? 44.126  -4.031  36.954  1.00 65.09  ? 317 GLU A N    1 
ATOM   799   C  CA   . GLU A 1 110 ? 44.467  -3.774  35.558  1.00 61.84  ? 317 GLU A CA   1 
ATOM   800   C  C    . GLU A 1 110 ? 43.937  -4.896  34.680  1.00 58.78  ? 317 GLU A C    1 
ATOM   801   O  O    . GLU A 1 110 ? 43.983  -6.069  35.057  1.00 57.68  ? 317 GLU A O    1 
ATOM   802   C  CB   . GLU A 1 110 ? 45.975  -3.659  35.379  1.00 57.74  ? 317 GLU A CB   1 
ATOM   803   C  CG   . GLU A 1 110 ? 46.396  -3.455  33.959  1.00 56.23  ? 317 GLU A CG   1 
ATOM   804   C  CD   . GLU A 1 110 ? 47.883  -3.225  33.835  1.00 61.68  ? 317 GLU A CD   1 
ATOM   805   O  OE1  . GLU A 1 110 ? 48.433  -3.456  32.738  1.00 60.14  ? 317 GLU A OE1  1 
ATOM   806   O  OE2  . GLU A 1 110 ? 48.506  -2.820  34.839  1.00 63.55  ? 317 GLU A OE2  1 
ATOM   807   N  N    . GLY A 1 111 ? 43.434  -4.536  33.503  1.00 58.85  ? 318 GLY A N    1 
ATOM   808   C  CA   . GLY A 1 111 ? 42.977  -5.519  32.547  1.00 47.70  ? 318 GLY A CA   1 
ATOM   809   C  C    . GLY A 1 111 ? 41.531  -5.926  32.694  1.00 51.54  ? 318 GLY A C    1 
ATOM   810   O  O    . GLY A 1 111 ? 41.062  -6.775  31.914  1.00 52.94  ? 318 GLY A O    1 
ATOM   811   N  N    . THR A 1 112 ? 40.798  -5.336  33.651  1.00 50.52  ? 319 THR A N    1 
ATOM   812   C  CA   . THR A 1 112 ? 39.432  -5.784  33.907  1.00 50.50  ? 319 THR A CA   1 
ATOM   813   C  C    . THR A 1 112 ? 38.524  -5.449  32.730  1.00 52.00  ? 319 THR A C    1 
ATOM   814   O  O    . THR A 1 112 ? 37.786  -6.312  32.227  1.00 53.96  ? 319 THR A O    1 
ATOM   815   C  CB   . THR A 1 112 ? 38.873  -5.178  35.207  1.00 53.76  ? 319 THR A CB   1 
ATOM   816   O  OG1  . THR A 1 112 ? 39.802  -5.354  36.281  1.00 56.47  ? 319 THR A OG1  1 
ATOM   817   C  CG2  . THR A 1 112 ? 37.588  -5.895  35.599  1.00 51.04  ? 319 THR A CG2  1 
ATOM   818   N  N    . ILE A 1 113 ? 38.574  -4.210  32.256  1.00 45.66  ? 320 ILE A N    1 
ATOM   819   C  CA   . ILE A 1 113 ? 37.695  -3.818  31.157  1.00 50.11  ? 320 ILE A CA   1 
ATOM   820   C  C    . ILE A 1 113 ? 37.953  -4.647  29.899  1.00 50.42  ? 320 ILE A C    1 
ATOM   821   O  O    . ILE A 1 113 ? 37.003  -5.268  29.393  1.00 48.80  ? 320 ILE A O    1 
ATOM   822   C  CB   . ILE A 1 113 ? 37.771  -2.298  30.944  1.00 49.10  ? 320 ILE A CB   1 
ATOM   823   C  CG1  . ILE A 1 113 ? 37.023  -1.625  32.108  1.00 46.93  ? 320 ILE A CG1  1 
ATOM   824   C  CG2  . ILE A 1 113 ? 37.186  -1.913  29.624  1.00 47.69  ? 320 ILE A CG2  1 
ATOM   825   C  CD1  . ILE A 1 113 ? 37.379  -0.164  32.301  1.00 54.31  ? 320 ILE A CD1  1 
ATOM   826   N  N    . PRO A 1 114 ? 39.192  -4.791  29.410  1.00 49.28  ? 321 PRO A N    1 
ATOM   827   C  CA   . PRO A 1 114 ? 39.380  -5.704  28.272  1.00 47.18  ? 321 PRO A CA   1 
ATOM   828   C  C    . PRO A 1 114 ? 38.995  -7.143  28.588  1.00 49.40  ? 321 PRO A C    1 
ATOM   829   O  O    . PRO A 1 114 ? 38.467  -7.829  27.710  1.00 46.43  ? 321 PRO A O    1 
ATOM   830   C  CB   . PRO A 1 114 ? 40.874  -5.549  27.920  1.00 51.74  ? 321 PRO A CB   1 
ATOM   831   C  CG   . PRO A 1 114 ? 41.508  -5.015  29.132  1.00 52.46  ? 321 PRO A CG   1 
ATOM   832   C  CD   . PRO A 1 114 ? 40.471  -4.198  29.856  1.00 51.36  ? 321 PRO A CD   1 
ATOM   833   N  N    . LYS A 1 115 ? 39.211  -7.628  29.813  1.00 53.66  ? 322 LYS A N    1 
ATOM   834   C  CA   . LYS A 1 115 ? 38.769  -8.988  30.125  1.00 47.07  ? 322 LYS A CA   1 
ATOM   835   C  C    . LYS A 1 115 ? 37.249  -9.127  29.978  1.00 47.07  ? 322 LYS A C    1 
ATOM   836   O  O    . LYS A 1 115 ? 36.750  -10.158 29.506  1.00 46.87  ? 322 LYS A O    1 
ATOM   837   C  CB   . LYS A 1 115 ? 39.226  -9.366  31.535  1.00 47.51  ? 322 LYS A CB   1 
ATOM   838   C  CG   . LYS A 1 115 ? 38.777  -10.769 31.992  1.00 53.80  ? 322 LYS A CG   1 
ATOM   839   C  CD   . LYS A 1 115 ? 39.348  -11.128 33.359  1.00 54.52  ? 322 LYS A CD   1 
ATOM   840   N  N    . LEU A 1 116 ? 36.496  -8.098  30.377  1.00 48.37  ? 323 LEU A N    1 
ATOM   841   C  CA   . LEU A 1 116 ? 35.036  -8.137  30.276  1.00 46.06  ? 323 LEU A CA   1 
ATOM   842   C  C    . LEU A 1 116 ? 34.568  -7.874  28.865  1.00 45.56  ? 323 LEU A C    1 
ATOM   843   O  O    . LEU A 1 116 ? 33.689  -8.584  28.362  1.00 51.54  ? 323 LEU A O    1 
ATOM   844   C  CB   . LEU A 1 116 ? 34.385  -7.098  31.185  1.00 46.79  ? 323 LEU A CB   1 
ATOM   845   C  CG   . LEU A 1 116 ? 34.514  -7.361  32.672  1.00 50.92  ? 323 LEU A CG   1 
ATOM   846   C  CD1  . LEU A 1 116 ? 33.823  -6.252  33.452  1.00 52.58  ? 323 LEU A CD1  1 
ATOM   847   C  CD2  . LEU A 1 116 ? 33.912  -8.720  32.983  1.00 55.28  ? 323 LEU A CD2  1 
ATOM   848   N  N    . PHE A 1 117 ? 35.136  -6.844  28.216  1.00 42.92  ? 324 PHE A N    1 
ATOM   849   C  CA   . PHE A 1 117 ? 34.509  -6.243  27.049  1.00 43.41  ? 324 PHE A CA   1 
ATOM   850   C  C    . PHE A 1 117 ? 35.260  -6.439  25.733  1.00 48.86  ? 324 PHE A C    1 
ATOM   851   O  O    . PHE A 1 117 ? 34.684  -6.165  24.682  1.00 44.72  ? 324 PHE A O    1 
ATOM   852   C  CB   . PHE A 1 117 ? 34.305  -4.741  27.285  1.00 42.04  ? 324 PHE A CB   1 
ATOM   853   C  CG   . PHE A 1 117 ? 33.396  -4.400  28.477  1.00 46.61  ? 324 PHE A CG   1 
ATOM   854   C  CD1  . PHE A 1 117 ? 32.026  -4.524  28.388  1.00 50.08  ? 324 PHE A CD1  1 
ATOM   855   C  CD2  . PHE A 1 117 ? 33.920  -3.918  29.655  1.00 47.08  ? 324 PHE A CD2  1 
ATOM   856   C  CE1  . PHE A 1 117 ? 31.191  -4.175  29.452  1.00 50.15  ? 324 PHE A CE1  1 
ATOM   857   C  CE2  . PHE A 1 117 ? 33.098  -3.583  30.721  1.00 52.81  ? 324 PHE A CE2  1 
ATOM   858   C  CZ   . PHE A 1 117 ? 31.722  -3.709  30.610  1.00 51.24  ? 324 PHE A CZ   1 
ATOM   859   N  N    . ARG A 1 118 ? 36.529  -6.841  25.774  1.00 47.27  ? 325 ARG A N    1 
ATOM   860   C  CA   . ARG A 1 118 ? 37.341  -6.848  24.528  1.00 45.86  ? 325 ARG A CA   1 
ATOM   861   C  C    . ARG A 1 118 ? 37.402  -8.178  23.800  1.00 44.06  ? 325 ARG A C    1 
ATOM   862   O  O    . ARG A 1 118 ? 37.772  -9.177  24.415  1.00 50.11  ? 325 ARG A O    1 
ATOM   863   C  CB   . ARG A 1 118 ? 38.775  -6.391  24.790  1.00 49.57  ? 325 ARG A CB   1 
ATOM   864   C  CG   . ARG A 1 118 ? 39.644  -6.264  23.551  1.00 47.41  ? 325 ARG A CG   1 
ATOM   865   C  CD   . ARG A 1 118 ? 41.041  -5.903  23.988  1.00 49.72  ? 325 ARG A CD   1 
ATOM   866   N  NE   . ARG A 1 118 ? 41.774  -7.051  24.491  1.00 55.89  ? 325 ARG A NE   1 
ATOM   867   C  CZ   . ARG A 1 118 ? 42.966  -6.983  25.067  1.00 48.71  ? 325 ARG A CZ   1 
ATOM   868   N  NH1  . ARG A 1 118 ? 43.569  -5.817  25.207  1.00 48.05  ? 325 ARG A NH1  1 
ATOM   869   N  NH2  . ARG A 1 118 ? 43.551  -8.081  25.503  1.00 53.68  ? 325 ARG A NH2  1 
ATOM   870   N  N    . GLY A 1 119 ? 37.049  -8.151  22.523  1.00 45.62  ? 326 GLY A N    1 
ATOM   871   C  CA   . GLY A 1 119 ? 37.184  -9.310  21.670  1.00 45.89  ? 326 GLY A CA   1 
ATOM   872   C  C    . GLY A 1 119 ? 38.150  -9.031  20.531  1.00 42.92  ? 326 GLY A C    1 
ATOM   873   O  O    . GLY A 1 119 ? 38.657  -7.919  20.391  1.00 48.58  ? 326 GLY A O    1 
ATOM   874   N  N    . LYS A 1 120 ? 38.363  -10.052 19.686  1.00 39.83  ? 327 LYS A N    1 
ATOM   875   C  CA   . LYS A 1 120 ? 39.213  -9.896  18.508  1.00 44.05  ? 327 LYS A CA   1 
ATOM   876   C  C    . LYS A 1 120 ? 38.510  -10.362 17.240  1.00 45.96  ? 327 LYS A C    1 
ATOM   877   O  O    . LYS A 1 120 ? 37.966  -11.474 17.189  1.00 46.51  ? 327 LYS A O    1 
ATOM   878   C  CB   . LYS A 1 120 ? 40.547  -10.640 18.663  1.00 49.06  ? 327 LYS A CB   1 
ATOM   879   C  CG   . LYS A 1 120 ? 41.605  -10.214 17.613  1.00 51.20  ? 327 LYS A CG   1 
ATOM   880   C  CD   . LYS A 1 120 ? 42.907  -9.660  18.252  1.00 52.61  ? 327 LYS A CD   1 
ATOM   881   N  N    . MET A 1 121 ? 38.560  -9.510  16.214  1.00 51.83  ? 328 MET A N    1 
ATOM   882   C  CA   . MET A 1 121 ? 38.107  -9.748  14.846  1.00 50.79  ? 328 MET A CA   1 
ATOM   883   C  C    . MET A 1 121 ? 39.273  -10.203 13.978  1.00 47.49  ? 328 MET A C    1 
ATOM   884   O  O    . MET A 1 121 ? 40.421  -9.816  14.200  1.00 44.07  ? 328 MET A O    1 
ATOM   885   C  CB   . MET A 1 121 ? 37.565  -8.453  14.227  1.00 44.35  ? 328 MET A CB   1 
ATOM   886   C  CG   . MET A 1 121 ? 36.080  -8.213  14.276  1.00 56.53  ? 328 MET A CG   1 
ATOM   887   S  SD   . MET A 1 121 ? 35.780  -6.450  13.977  1.00 65.16  ? 328 MET A SD   1 
ATOM   888   C  CE   . MET A 1 121 ? 37.143  -6.089  12.842  1.00 49.27  ? 328 MET A CE   1 
ATOM   889   N  N    . VAL A 1 122 ? 38.965  -10.918 12.902  1.00 48.98  ? 329 VAL A N    1 
ATOM   890   C  CA   . VAL A 1 122 ? 39.955  -11.133 11.854  1.00 42.53  ? 329 VAL A CA   1 
ATOM   891   C  C    . VAL A 1 122 ? 39.336  -10.756 10.521  1.00 45.41  ? 329 VAL A C    1 
ATOM   892   O  O    . VAL A 1 122 ? 38.152  -11.028 10.284  1.00 49.79  ? 329 VAL A O    1 
ATOM   893   C  CB   . VAL A 1 122 ? 40.481  -12.583 11.849  1.00 45.39  ? 329 VAL A CB   1 
ATOM   894   C  CG1  . VAL A 1 122 ? 39.367  -13.580 11.499  1.00 46.71  ? 329 VAL A CG1  1 
ATOM   895   C  CG2  . VAL A 1 122 ? 41.679  -12.709 10.907  1.00 48.94  ? 329 VAL A CG2  1 
ATOM   896   N  N    . SER A 1 123 ? 40.127  -10.122 9.646   1.00 38.51  ? 330 SER A N    1 
ATOM   897   C  CA   . SER A 1 123 ? 39.669  -9.814  8.292   1.00 46.39  ? 330 SER A CA   1 
ATOM   898   C  C    . SER A 1 123 ? 40.601  -10.454 7.277   1.00 50.44  ? 330 SER A C    1 
ATOM   899   O  O    . SER A 1 123 ? 41.804  -10.184 7.284   1.00 49.53  ? 330 SER A O    1 
ATOM   900   C  CB   . SER A 1 123 ? 39.581  -8.310  8.027   1.00 47.25  ? 330 SER A CB   1 
ATOM   901   O  OG   . SER A 1 123 ? 39.030  -7.640  9.132   1.00 55.44  ? 330 SER A OG   1 
ATOM   902   N  N    . TYR A 1 124 ? 40.022  -11.263 6.386   1.00 58.24  ? 331 TYR A N    1 
ATOM   903   C  CA   . TYR A 1 124 ? 40.722  -11.977 5.323   1.00 56.05  ? 331 TYR A CA   1 
ATOM   904   C  C    . TYR A 1 124 ? 40.515  -11.233 4.017   1.00 53.37  ? 331 TYR A C    1 
ATOM   905   O  O    . TYR A 1 124 ? 39.385  -10.869 3.685   1.00 53.37  ? 331 TYR A O    1 
ATOM   906   C  CB   . TYR A 1 124 ? 40.186  -13.404 5.189   1.00 55.49  ? 331 TYR A CB   1 
ATOM   907   C  CG   . TYR A 1 124 ? 40.312  -14.222 6.458   1.00 63.87  ? 331 TYR A CG   1 
ATOM   908   C  CD1  . TYR A 1 124 ? 41.561  -14.453 7.025   1.00 60.30  ? 331 TYR A CD1  1 
ATOM   909   C  CD2  . TYR A 1 124 ? 39.190  -14.765 7.091   1.00 59.90  ? 331 TYR A CD2  1 
ATOM   910   C  CE1  . TYR A 1 124 ? 41.701  -15.205 8.184   1.00 57.27  ? 331 TYR A CE1  1 
ATOM   911   C  CE2  . TYR A 1 124 ? 39.321  -15.520 8.267   1.00 57.12  ? 331 TYR A CE2  1 
ATOM   912   C  CZ   . TYR A 1 124 ? 40.584  -15.731 8.806   1.00 60.67  ? 331 TYR A CZ   1 
ATOM   913   O  OH   . TYR A 1 124 ? 40.754  -16.467 9.963   1.00 61.91  ? 331 TYR A OH   1 
ATOM   914   N  N    . ILE A 1 125 ? 41.594  -11.028 3.272   1.00 58.17  ? 332 ILE A N    1 
ATOM   915   C  CA   . ILE A 1 125 ? 41.544  -10.367 1.969   1.00 56.45  ? 332 ILE A CA   1 
ATOM   916   C  C    . ILE A 1 125 ? 42.183  -11.280 0.943   1.00 50.96  ? 332 ILE A C    1 
ATOM   917   O  O    . ILE A 1 125 ? 43.358  -11.633 1.081   1.00 59.26  ? 332 ILE A O    1 
ATOM   918   C  CB   . ILE A 1 125 ? 42.269  -9.018  1.983   1.00 52.12  ? 332 ILE A CB   1 
ATOM   919   C  CG1  . ILE A 1 125 ? 41.540  -8.041  2.901   1.00 49.72  ? 332 ILE A CG1  1 
ATOM   920   C  CG2  . ILE A 1 125 ? 42.396  -8.490  0.565   1.00 52.94  ? 332 ILE A CG2  1 
ATOM   921   C  CD1  . ILE A 1 125 ? 42.452  -6.940  3.441   1.00 53.22  ? 332 ILE A CD1  1 
ATOM   922   N  N    . GLN A 1 126 ? 41.437  -11.614 -0.109  1.00 54.73  ? 333 GLN A N    1 
ATOM   923   C  CA   . GLN A 1 126 ? 41.894  -12.531 -1.155  1.00 55.25  ? 333 GLN A CA   1 
ATOM   924   C  C    . GLN A 1 126 ? 41.713  -11.897 -2.532  1.00 52.83  ? 333 GLN A C    1 
ATOM   925   O  O    . GLN A 1 126 ? 40.575  -11.673 -2.962  1.00 54.55  ? 333 GLN A O    1 
ATOM   926   C  CB   . GLN A 1 126 ? 41.121  -13.848 -1.071  1.00 52.56  ? 333 GLN A CB   1 
ATOM   927   C  CG   . GLN A 1 126 ? 41.182  -14.694 -2.300  1.00 53.42  ? 333 GLN A CG   1 
ATOM   928   C  CD   . GLN A 1 126 ? 42.417  -15.532 -2.319  1.00 64.49  ? 333 GLN A CD   1 
ATOM   929   O  OE1  . GLN A 1 126 ? 42.445  -16.628 -1.745  1.00 72.42  ? 333 GLN A OE1  1 
ATOM   930   N  NE2  . GLN A 1 126 ? 43.471  -15.024 -2.973  1.00 64.37  ? 333 GLN A NE2  1 
ATOM   931   N  N    . CYS A 1 127 ? 42.823  -11.612 -3.228  1.00 50.05  ? 334 CYS A N    1 
ATOM   932   C  CA   . CYS A 1 127 ? 42.732  -11.128 -4.610  1.00 56.12  ? 334 CYS A CA   1 
ATOM   933   C  C    . CYS A 1 127 ? 42.094  -12.168 -5.518  1.00 53.37  ? 334 CYS A C    1 
ATOM   934   O  O    . CYS A 1 127 ? 42.315  -13.372 -5.371  1.00 60.43  ? 334 CYS A O    1 
ATOM   935   C  CB   . CYS A 1 127 ? 44.095  -10.762 -5.171  1.00 46.71  ? 334 CYS A CB   1 
ATOM   936   S  SG   . CYS A 1 127 ? 44.808  -9.347  -4.348  1.00 53.41  ? 334 CYS A SG   1 
ATOM   937   N  N    . LYS A 1 128 ? 41.327  -11.704 -6.491  1.00 55.14  ? 335 LYS A N    1 
ATOM   938   C  CA   . LYS A 1 128 ? 40.558  -12.646 -7.331  1.00 56.80  ? 335 LYS A CA   1 
ATOM   939   C  C    . LYS A 1 128 ? 41.289  -12.966 -8.637  1.00 64.36  ? 335 LYS A C    1 
ATOM   940   O  O    . LYS A 1 128 ? 40.987  -14.017 -9.221  1.00 68.82  ? 335 LYS A O    1 
ATOM   941   C  CB   . LYS A 1 128 ? 39.184  -12.028 -7.581  1.00 52.95  ? 335 LYS A CB   1 
ATOM   942   N  N    . GLU A 1 129 ? 42.202  -12.105 -9.079  1.00 65.07  ? 336 GLU A N    1 
ATOM   943   C  CA   . GLU A 1 129 ? 42.864  -12.316 -10.390 1.00 67.36  ? 336 GLU A CA   1 
ATOM   944   C  C    . GLU A 1 129 ? 44.376  -12.391 -10.201 1.00 69.27  ? 336 GLU A C    1 
ATOM   945   O  O    . GLU A 1 129 ? 45.086  -12.307 -11.208 1.00 77.34  ? 336 GLU A O    1 
ATOM   946   C  CB   . GLU A 1 129 ? 42.486  -11.194 -11.354 1.00 65.07  ? 336 GLU A CB   1 
ATOM   947   C  CG   . GLU A 1 129 ? 41.042  -11.237 -11.816 1.00 70.27  ? 336 GLU A CG   1 
ATOM   948   C  CD   . GLU A 1 129 ? 40.665  -12.431 -12.675 1.00 83.10  ? 336 GLU A CD   1 
ATOM   949   O  OE1  . GLU A 1 129 ? 41.486  -12.841 -13.518 1.00 84.09  ? 336 GLU A OE1  1 
ATOM   950   O  OE2  . GLU A 1 129 ? 39.544  -12.942 -12.504 1.00 88.79  ? 336 GLU A OE2  1 
ATOM   951   N  N    . VAL A 1 130 ? 44.835  -12.554 -8.966  1.00 64.01  ? 337 VAL A N    1 
ATOM   952   C  CA   . VAL A 1 130 ? 46.289  -12.694 -8.677  1.00 62.79  ? 337 VAL A CA   1 
ATOM   953   C  C    . VAL A 1 130 ? 46.435  -13.462 -7.356  1.00 69.79  ? 337 VAL A C    1 
ATOM   954   O  O    . VAL A 1 130 ? 45.510  -13.416 -6.535  1.00 68.73  ? 337 VAL A O    1 
ATOM   955   C  CB   . VAL A 1 130 ? 46.987  -11.320 -8.681  1.00 65.21  ? 337 VAL A CB   1 
ATOM   956   C  CG1  . VAL A 1 130 ? 47.374  -10.811 -7.305  1.00 66.85  ? 337 VAL A CG1  1 
ATOM   957   C  CG2  . VAL A 1 130 ? 48.168  -11.287 -9.632  1.00 66.24  ? 337 VAL A CG2  1 
ATOM   958   N  N    . ASP A 1 131 ? 47.530  -14.200 -7.187  1.00 74.44  ? 338 ASP A N    1 
ATOM   959   C  CA   . ASP A 1 131 ? 47.771  -14.932 -5.917  1.00 75.09  ? 338 ASP A CA   1 
ATOM   960   C  C    . ASP A 1 131 ? 48.294  -13.961 -4.855  1.00 74.28  ? 338 ASP A C    1 
ATOM   961   O  O    . ASP A 1 131 ? 49.522  -13.862 -4.709  1.00 75.58  ? 338 ASP A O    1 
ATOM   962   C  CB   . ASP A 1 131 ? 48.706  -16.124 -6.127  1.00 76.83  ? 338 ASP A CB   1 
ATOM   963   C  CG   . ASP A 1 131 ? 48.282  -17.355 -5.350  1.00 84.02  ? 338 ASP A CG   1 
ATOM   964   O  OD1  . ASP A 1 131 ? 48.345  -17.313 -4.109  1.00 84.25  ? 338 ASP A OD1  1 
ATOM   965   O  OD2  . ASP A 1 131 ? 47.892  -18.344 -5.995  1.00 84.61  ? 338 ASP A OD2  1 
ATOM   966   N  N    . TYR A 1 132 ? 47.393  -13.269 -4.158  1.00 68.84  ? 339 TYR A N    1 
ATOM   967   C  CA   . TYR A 1 132 ? 47.798  -12.356 -3.060  1.00 66.11  ? 339 TYR A CA   1 
ATOM   968   C  C    . TYR A 1 132 ? 46.748  -12.415 -1.950  1.00 69.74  ? 339 TYR A C    1 
ATOM   969   O  O    . TYR A 1 132 ? 45.592  -12.054 -2.198  1.00 63.81  ? 339 TYR A O    1 
ATOM   970   C  CB   . TYR A 1 132 ? 48.033  -10.937 -3.576  1.00 58.87  ? 339 TYR A CB   1 
ATOM   971   C  CG   . TYR A 1 132 ? 48.841  -10.027 -2.691  1.00 61.10  ? 339 TYR A CG   1 
ATOM   972   C  CD1  . TYR A 1 132 ? 48.264  -9.368  -1.621  1.00 58.23  ? 339 TYR A CD1  1 
ATOM   973   C  CD2  . TYR A 1 132 ? 50.179  -9.794  -2.948  1.00 60.35  ? 339 TYR A CD2  1 
ATOM   974   C  CE1  . TYR A 1 132 ? 49.000  -8.517  -0.816  1.00 56.91  ? 339 TYR A CE1  1 
ATOM   975   C  CE2  . TYR A 1 132 ? 50.929  -8.942  -2.157  1.00 58.31  ? 339 TYR A CE2  1 
ATOM   976   C  CZ   . TYR A 1 132 ? 50.336  -8.301  -1.087  1.00 54.41  ? 339 TYR A CZ   1 
ATOM   977   O  OH   . TYR A 1 132 ? 51.067  -7.460  -0.302  1.00 57.69  ? 339 TYR A OH   1 
ATOM   978   N  N    . ARG A 1 133 ? 47.150  -12.883 -0.772  1.00 67.66  ? 340 ARG A N    1 
ATOM   979   C  CA   . ARG A 1 133 ? 46.269  -12.945 0.391   1.00 60.84  ? 340 ARG A CA   1 
ATOM   980   C  C    . ARG A 1 133 ? 46.849  -12.071 1.487   1.00 58.62  ? 340 ARG A C    1 
ATOM   981   O  O    . ARG A 1 133 ? 48.065  -11.874 1.540   1.00 65.54  ? 340 ARG A O    1 
ATOM   982   C  CB   . ARG A 1 133 ? 46.147  -14.366 0.935   1.00 58.88  ? 340 ARG A CB   1 
ATOM   983   C  CG   . ARG A 1 133 ? 45.081  -15.215 0.275   1.00 65.69  ? 340 ARG A CG   1 
ATOM   984   C  CD   . ARG A 1 133 ? 45.195  -16.650 0.756   1.00 72.84  ? 340 ARG A CD   1 
ATOM   985   N  NE   . ARG A 1 133 ? 46.448  -17.268 0.322   1.00 77.10  ? 340 ARG A NE   1 
ATOM   986   C  CZ   . ARG A 1 133 ? 46.619  -17.854 -0.862  1.00 82.19  ? 340 ARG A CZ   1 
ATOM   987   N  NH1  . ARG A 1 133 ? 45.606  -17.899 -1.726  1.00 78.66  ? 340 ARG A NH1  1 
ATOM   988   N  NH2  . ARG A 1 133 ? 47.800  -18.390 -1.187  1.00 80.83  ? 340 ARG A NH2  1 
ATOM   989   N  N    . SER A 1 134 ? 45.993  -11.557 2.375   1.00 54.89  ? 341 SER A N    1 
ATOM   990   C  CA   . SER A 1 134 ? 46.505  -10.829 3.535   1.00 58.56  ? 341 SER A CA   1 
ATOM   991   C  C    . SER A 1 134 ? 45.519  -10.928 4.701   1.00 53.88  ? 341 SER A C    1 
ATOM   992   O  O    . SER A 1 134 ? 44.414  -11.451 4.565   1.00 52.88  ? 341 SER A O    1 
ATOM   993   C  CB   . SER A 1 134 ? 46.826  -9.368  3.181   1.00 53.53  ? 341 SER A CB   1 
ATOM   994   O  OG   . SER A 1 134 ? 46.963  -8.591  4.350   1.00 58.32  ? 341 SER A OG   1 
ATOM   995   N  N    . ASP A 1 135 ? 45.927  -10.377 5.846   1.00 55.99  ? 342 ASP A N    1 
ATOM   996   C  CA   . ASP A 1 135 ? 45.358  -10.717 7.145   1.00 56.78  ? 342 ASP A CA   1 
ATOM   997   C  C    . ASP A 1 135 ? 45.362  -9.523  8.063   1.00 53.81  ? 342 ASP A C    1 
ATOM   998   O  O    . ASP A 1 135 ? 46.377  -8.833  8.174   1.00 61.51  ? 342 ASP A O    1 
ATOM   999   C  CB   . ASP A 1 135 ? 46.188  -11.791 7.864   1.00 60.55  ? 342 ASP A CB   1 
ATOM   1000  C  CG   . ASP A 1 135 ? 45.530  -13.096 7.837   1.00 58.38  ? 342 ASP A CG   1 
ATOM   1001  O  OD1  . ASP A 1 135 ? 44.298  -13.065 7.596   1.00 60.37  ? 342 ASP A OD1  1 
ATOM   1002  O  OD2  . ASP A 1 135 ? 46.229  -14.117 7.997   1.00 59.45  ? 342 ASP A OD2  1 
ATOM   1003  N  N    . ARG A 1 136 ? 44.293  -9.345  8.829   1.00 50.17  ? 343 ARG A N    1 
ATOM   1004  C  CA   . ARG A 1 136 ? 44.327  -8.276  9.857   1.00 52.66  ? 343 ARG A CA   1 
ATOM   1005  C  C    . ARG A 1 136 ? 43.483  -8.682  11.065  1.00 51.33  ? 343 ARG A C    1 
ATOM   1006  O  O    . ARG A 1 136 ? 42.332  -9.047  10.879  1.00 51.14  ? 343 ARG A O    1 
ATOM   1007  C  CB   . ARG A 1 136 ? 43.891  -6.928  9.289   1.00 52.11  ? 343 ARG A CB   1 
ATOM   1008  C  CG   . ARG A 1 136 ? 44.313  -5.758  10.158  1.00 51.46  ? 343 ARG A CG   1 
ATOM   1009  C  CD   . ARG A 1 136 ? 45.786  -5.896  10.459  1.00 58.91  ? 343 ARG A CD   1 
ATOM   1010  N  NE   . ARG A 1 136 ? 46.461  -4.714  9.975   1.00 53.48  ? 343 ARG A NE   1 
ATOM   1011  C  CZ   . ARG A 1 136 ? 46.789  -3.687  10.737  1.00 64.67  ? 343 ARG A CZ   1 
ATOM   1012  N  NH1  . ARG A 1 136 ? 46.518  -3.696  12.031  1.00 56.57  ? 343 ARG A NH1  1 
ATOM   1013  N  NH2  . ARG A 1 136 ? 47.387  -2.648  10.199  1.00 69.67  ? 343 ARG A NH2  1 
ATOM   1014  N  N    . ARG A 1 137 ? 44.059  -8.590  12.256  1.00 48.48  ? 344 ARG A N    1 
ATOM   1015  C  CA   . ARG A 1 137 ? 43.351  -8.967  13.498  1.00 50.71  ? 344 ARG A CA   1 
ATOM   1016  C  C    . ARG A 1 137 ? 43.245  -7.745  14.398  1.00 55.97  ? 344 ARG A C    1 
ATOM   1017  O  O    . ARG A 1 137 ? 44.295  -7.211  14.770  1.00 60.97  ? 344 ARG A O    1 
ATOM   1018  C  CB   . ARG A 1 137 ? 44.108  -10.081 14.214  1.00 50.15  ? 344 ARG A CB   1 
ATOM   1019  C  CG   . ARG A 1 137 ? 43.886  -11.447 13.601  1.00 46.95  ? 344 ARG A CG   1 
ATOM   1020  C  CD   . ARG A 1 137 ? 45.083  -12.338 13.803  1.00 46.35  ? 344 ARG A CD   1 
ATOM   1021  N  NE   . ARG A 1 137 ? 44.943  -13.484 12.928  1.00 50.55  ? 344 ARG A NE   1 
ATOM   1022  C  CZ   . ARG A 1 137 ? 45.393  -13.538 11.687  1.00 49.43  ? 344 ARG A CZ   1 
ATOM   1023  N  NH1  . ARG A 1 137 ? 45.208  -14.631 10.971  1.00 52.81  ? 344 ARG A NH1  1 
ATOM   1024  N  NH2  . ARG A 1 137 ? 46.039  -12.510 11.171  1.00 52.13  ? 344 ARG A NH2  1 
ATOM   1025  N  N    . GLU A 1 138 ? 42.026  -7.328  14.737  1.00 49.40  ? 345 GLU A N    1 
ATOM   1026  C  CA   . GLU A 1 138 ? 41.878  -6.113  15.515  1.00 49.68  ? 345 GLU A CA   1 
ATOM   1027  C  C    . GLU A 1 138 ? 40.971  -6.380  16.709  1.00 50.26  ? 345 GLU A C    1 
ATOM   1028  O  O    . GLU A 1 138 ? 39.999  -7.144  16.624  1.00 53.04  ? 345 GLU A O    1 
ATOM   1029  C  CB   . GLU A 1 138 ? 41.366  -4.956  14.624  1.00 51.73  ? 345 GLU A CB   1 
ATOM   1030  C  CG   . GLU A 1 138 ? 42.335  -4.684  13.445  1.00 52.02  ? 345 GLU A CG   1 
ATOM   1031  C  CD   . GLU A 1 138 ? 41.736  -3.898  12.281  1.00 55.68  ? 345 GLU A CD   1 
ATOM   1032  O  OE1  . GLU A 1 138 ? 40.871  -4.435  11.546  1.00 55.02  ? 345 GLU A OE1  1 
ATOM   1033  O  OE2  . GLU A 1 138 ? 42.165  -2.745  12.083  1.00 53.89  ? 345 GLU A OE2  1 
ATOM   1034  N  N    . ASP A 1 139 ? 41.338  -5.729  17.794  1.00 40.29  ? 346 ASP A N    1 
ATOM   1035  C  CA   . ASP A 1 139 ? 40.533  -5.835  19.013  1.00 42.33  ? 346 ASP A CA   1 
ATOM   1036  C  C    . ASP A 1 139 ? 39.305  -4.946  18.872  1.00 50.33  ? 346 ASP A C    1 
ATOM   1037  O  O    . ASP A 1 139 ? 39.360  -3.995  18.106  1.00 55.13  ? 346 ASP A O    1 
ATOM   1038  C  CB   . ASP A 1 139 ? 41.400  -5.433  20.202  1.00 48.71  ? 346 ASP A CB   1 
ATOM   1039  C  CG   . ASP A 1 139 ? 42.457  -6.447  20.581  1.00 45.97  ? 346 ASP A CG   1 
ATOM   1040  O  OD1  . ASP A 1 139 ? 42.137  -7.637  20.604  1.00 44.59  ? 346 ASP A OD1  1 
ATOM   1041  O  OD2  . ASP A 1 139 ? 43.580  -6.027  20.878  1.00 58.92  ? 346 ASP A OD2  1 
ATOM   1042  N  N    . TYR A 1 140 ? 38.193  -5.331  19.472  1.00 49.42  ? 347 TYR A N    1 
ATOM   1043  C  CA   . TYR A 1 140 ? 36.994  -4.505  19.548  1.00 42.71  ? 347 TYR A CA   1 
ATOM   1044  C  C    . TYR A 1 140 ? 36.492  -4.527  20.983  1.00 46.84  ? 347 TYR A C    1 
ATOM   1045  O  O    . TYR A 1 140 ? 36.802  -5.428  21.765  1.00 46.86  ? 347 TYR A O    1 
ATOM   1046  C  CB   . TYR A 1 140 ? 35.881  -4.985  18.589  1.00 44.22  ? 347 TYR A CB   1 
ATOM   1047  C  CG   . TYR A 1 140 ? 35.420  -6.407  18.841  1.00 41.46  ? 347 TYR A CG   1 
ATOM   1048  C  CD1  . TYR A 1 140 ? 36.109  -7.497  18.307  1.00 43.43  ? 347 TYR A CD1  1 
ATOM   1049  C  CD2  . TYR A 1 140 ? 34.304  -6.660  19.608  1.00 44.76  ? 347 TYR A CD2  1 
ATOM   1050  C  CE1  . TYR A 1 140 ? 35.685  -8.799  18.535  1.00 40.90  ? 347 TYR A CE1  1 
ATOM   1051  C  CE2  . TYR A 1 140 ? 33.866  -7.942  19.833  1.00 43.50  ? 347 TYR A CE2  1 
ATOM   1052  C  CZ   . TYR A 1 140 ? 34.564  -9.014  19.311  1.00 47.82  ? 347 TYR A CZ   1 
ATOM   1053  O  OH   . TYR A 1 140 ? 34.098  -10.297 19.579  1.00 47.03  ? 347 TYR A OH   1 
ATOM   1054  N  N    . TYR A 1 141 ? 35.668  -3.537  21.307  1.00 48.11  ? 348 TYR A N    1 
ATOM   1055  C  CA   . TYR A 1 141 ? 35.045  -3.449  22.645  1.00 43.39  ? 348 TYR A CA   1 
ATOM   1056  C  C    . TYR A 1 141 ? 33.531  -3.385  22.451  1.00 45.15  ? 348 TYR A C    1 
ATOM   1057  O  O    . TYR A 1 141 ? 32.822  -3.484  23.453  1.00 44.32  ? 348 TYR A O    1 
ATOM   1058  C  CB   . TYR A 1 141 ? 35.596  -2.228  23.372  1.00 47.56  ? 348 TYR A CB   1 
ATOM   1059  C  CG   . TYR A 1 141 ? 36.947  -2.387  24.020  1.00 49.71  ? 348 TYR A CG   1 
ATOM   1060  C  CD1  . TYR A 1 141 ? 38.108  -2.343  23.270  1.00 48.14  ? 348 TYR A CD1  1 
ATOM   1061  C  CD2  . TYR A 1 141 ? 37.066  -2.541  25.389  1.00 49.21  ? 348 TYR A CD2  1 
ATOM   1062  C  CE1  . TYR A 1 141 ? 39.353  -2.463  23.857  1.00 50.19  ? 348 TYR A CE1  1 
ATOM   1063  C  CE2  . TYR A 1 141 ? 38.305  -2.666  25.994  1.00 54.41  ? 348 TYR A CE2  1 
ATOM   1064  C  CZ   . TYR A 1 141 ? 39.452  -2.627  25.224  1.00 54.02  ? 348 TYR A CZ   1 
ATOM   1065  O  OH   . TYR A 1 141 ? 40.678  -2.751  25.802  1.00 61.77  ? 348 TYR A OH   1 
ATOM   1066  N  N    . ASP A 1 142 ? 33.065  -3.199  21.216  1.00 44.12  ? 349 ASP A N    1 
ATOM   1067  C  CA   . ASP A 1 142 ? 31.659  -3.208  20.866  1.00 46.03  ? 349 ASP A CA   1 
ATOM   1068  C  C    . ASP A 1 142 ? 31.593  -3.556  19.387  1.00 52.69  ? 349 ASP A C    1 
ATOM   1069  O  O    . ASP A 1 142 ? 32.628  -3.640  18.709  1.00 45.31  ? 349 ASP A O    1 
ATOM   1070  C  CB   . ASP A 1 142 ? 30.986  -1.877  21.215  1.00 45.07  ? 349 ASP A CB   1 
ATOM   1071  C  CG   . ASP A 1 142 ? 31.438  -0.696  20.344  1.00 51.06  ? 349 ASP A CG   1 
ATOM   1072  O  OD1  . ASP A 1 142 ? 32.366  -0.797  19.501  1.00 52.12  ? 349 ASP A OD1  1 
ATOM   1073  O  OD2  . ASP A 1 142 ? 30.815  0.381   20.510  1.00 51.23  ? 349 ASP A OD2  1 
ATOM   1074  N  N    . ILE A 1 143 ? 30.372  -3.792  18.897  1.00 49.37  ? 350 ILE A N    1 
ATOM   1075  C  CA   . ILE A 1 143 ? 30.157  -4.201  17.506  1.00 42.24  ? 350 ILE A CA   1 
ATOM   1076  C  C    . ILE A 1 143 ? 29.053  -3.335  16.892  1.00 48.68  ? 350 ILE A C    1 
ATOM   1077  O  O    . ILE A 1 143 ? 27.928  -3.271  17.414  1.00 42.93  ? 350 ILE A O    1 
ATOM   1078  C  CB   . ILE A 1 143 ? 29.801  -5.693  17.398  1.00 40.16  ? 350 ILE A CB   1 
ATOM   1079  C  CG1  . ILE A 1 143 ? 30.901  -6.561  18.004  1.00 45.92  ? 350 ILE A CG1  1 
ATOM   1080  C  CG2  . ILE A 1 143 ? 29.549  -6.108  15.951  1.00 39.85  ? 350 ILE A CG2  1 
ATOM   1081  C  CD1  . ILE A 1 143 ? 30.467  -8.049  18.232  1.00 43.00  ? 350 ILE A CD1  1 
ATOM   1082  N  N    . GLN A 1 144 ? 29.370  -2.677  15.785  1.00 46.24  ? 351 GLN A N    1 
ATOM   1083  C  CA   . GLN A 1 144 ? 28.375  -1.919  15.045  1.00 43.22  ? 351 GLN A CA   1 
ATOM   1084  C  C    . GLN A 1 144 ? 27.640  -2.866  14.110  1.00 46.26  ? 351 GLN A C    1 
ATOM   1085  O  O    . GLN A 1 144 ? 28.266  -3.492  13.248  1.00 51.37  ? 351 GLN A O    1 
ATOM   1086  C  CB   . GLN A 1 144 ? 29.049  -0.802  14.253  1.00 41.81  ? 351 GLN A CB   1 
ATOM   1087  C  CG   . GLN A 1 144 ? 29.616  0.315   15.091  1.00 42.82  ? 351 GLN A CG   1 
ATOM   1088  C  CD   . GLN A 1 144 ? 30.835  -0.106  15.932  1.00 47.03  ? 351 GLN A CD   1 
ATOM   1089  O  OE1  . GLN A 1 144 ? 31.782  -0.707  15.428  1.00 46.39  ? 351 GLN A OE1  1 
ATOM   1090  N  NE2  . GLN A 1 144 ? 30.791  0.195   17.228  1.00 45.78  ? 351 GLN A NE2  1 
ATOM   1091  N  N    . LEU A 1 145 ? 26.328  -2.990  14.290  1.00 50.19  ? 352 LEU A N    1 
ATOM   1092  C  CA   . LEU A 1 145 ? 25.528  -3.965  13.510  1.00 46.78  ? 352 LEU A CA   1 
ATOM   1093  C  C    . LEU A 1 145 ? 24.524  -3.238  12.617  1.00 51.50  ? 352 LEU A C    1 
ATOM   1094  O  O    . LEU A 1 145 ? 23.649  -2.561  13.159  1.00 49.92  ? 352 LEU A O    1 
ATOM   1095  C  CB   . LEU A 1 145 ? 24.793  -4.869  14.499  1.00 45.63  ? 352 LEU A CB   1 
ATOM   1096  C  CG   . LEU A 1 145 ? 25.591  -6.018  15.108  1.00 52.30  ? 352 LEU A CG   1 
ATOM   1097  C  CD1  . LEU A 1 145 ? 24.718  -6.812  16.062  1.00 47.84  ? 352 LEU A CD1  1 
ATOM   1098  C  CD2  . LEU A 1 145 ? 26.150  -6.928  14.028  1.00 44.93  ? 352 LEU A CD2  1 
ATOM   1099  N  N    . SER A 1 146 ? 24.619  -3.431  11.303  1.00 55.02  ? 353 SER A N    1 
ATOM   1100  C  CA   . SER A 1 146 ? 23.696  -2.783  10.333  1.00 58.12  ? 353 SER A CA   1 
ATOM   1101  C  C    . SER A 1 146 ? 22.238  -3.209  10.560  1.00 57.54  ? 353 SER A C    1 
ATOM   1102  O  O    . SER A 1 146 ? 22.010  -4.367  10.935  1.00 57.72  ? 353 SER A O    1 
ATOM   1103  C  CB   . SER A 1 146 ? 24.147  -3.032  8.929   1.00 55.80  ? 353 SER A CB   1 
ATOM   1104  O  OG   . SER A 1 146 ? 23.838  -1.922  8.102   1.00 65.81  ? 353 SER A OG   1 
ATOM   1105  N  N    . ILE A 1 147 ? 21.285  -2.305  10.313  1.00 57.14  ? 354 ILE A N    1 
ATOM   1106  C  CA   . ILE A 1 147 ? 19.850  -2.578  10.627  1.00 60.29  ? 354 ILE A CA   1 
ATOM   1107  C  C    . ILE A 1 147 ? 18.987  -2.526  9.372   1.00 56.86  ? 354 ILE A C    1 
ATOM   1108  O  O    . ILE A 1 147 ? 18.103  -3.379  9.246   1.00 52.98  ? 354 ILE A O    1 
ATOM   1109  C  CB   . ILE A 1 147 ? 19.345  -1.533  11.646  1.00 61.57  ? 354 ILE A CB   1 
ATOM   1110  C  CG1  . ILE A 1 147 ? 20.195  -1.505  12.915  1.00 60.63  ? 354 ILE A CG1  1 
ATOM   1111  C  CG2  . ILE A 1 147 ? 17.872  -1.712  11.979  1.00 52.22  ? 354 ILE A CG2  1 
ATOM   1112  C  CD1  . ILE A 1 147 ? 20.258  -2.823  13.617  1.00 55.25  ? 354 ILE A CD1  1 
ATOM   1113  N  N    . LYS A 1 148 ? 19.245  -1.582  8.465   1.00 56.41  ? 355 LYS A N    1 
ATOM   1114  C  CA   . LYS A 1 148 ? 18.308  -1.419  7.358   1.00 62.97  ? 355 LYS A CA   1 
ATOM   1115  C  C    . LYS A 1 148 ? 18.283  -2.645  6.452   1.00 65.54  ? 355 LYS A C    1 
ATOM   1116  O  O    . LYS A 1 148 ? 19.321  -3.099  5.954   1.00 69.71  ? 355 LYS A O    1 
ATOM   1117  C  CB   . LYS A 1 148 ? 18.661  -0.175  6.544   1.00 60.45  ? 355 LYS A CB   1 
ATOM   1118  C  CG   . LYS A 1 148 ? 17.439  0.514   5.949   1.00 58.47  ? 355 LYS A CG   1 
ATOM   1119  N  N    . GLY A 1 149 ? 17.088  -3.170  6.225   1.00 58.14  ? 356 GLY A N    1 
ATOM   1120  C  CA   . GLY A 1 149 ? 16.924  -4.334  5.392   1.00 60.17  ? 356 GLY A CA   1 
ATOM   1121  C  C    . GLY A 1 149 ? 17.143  -5.647  6.100   1.00 62.68  ? 356 GLY A C    1 
ATOM   1122  O  O    . GLY A 1 149 ? 16.983  -6.705  5.474   1.00 62.84  ? 356 GLY A O    1 
ATOM   1123  N  N    . LYS A 1 150 ? 17.500  -5.617  7.377   1.00 62.08  ? 357 LYS A N    1 
ATOM   1124  C  CA   . LYS A 1 150 ? 17.727  -6.820  8.160   1.00 60.43  ? 357 LYS A CA   1 
ATOM   1125  C  C    . LYS A 1 150 ? 16.556  -7.021  9.113   1.00 61.99  ? 357 LYS A C    1 
ATOM   1126  O  O    . LYS A 1 150 ? 16.122  -6.081  9.787   1.00 65.06  ? 357 LYS A O    1 
ATOM   1127  C  CB   . LYS A 1 150 ? 19.058  -6.740  8.919   1.00 61.64  ? 357 LYS A CB   1 
ATOM   1128  C  CG   . LYS A 1 150 ? 20.317  -6.658  8.023   1.00 59.23  ? 357 LYS A CG   1 
ATOM   1129  C  CD   . LYS A 1 150 ? 20.736  -5.219  7.756   1.00 65.03  ? 357 LYS A CD   1 
ATOM   1130  C  CE   . LYS A 1 150 ? 21.701  -5.099  6.566   1.00 71.67  ? 357 LYS A CE   1 
ATOM   1131  N  NZ   . LYS A 1 150 ? 21.081  -5.523  5.262   1.00 77.04  ? 357 LYS A NZ   1 
ATOM   1132  N  N    . LYS A 1 151 ? 16.027  -8.239  9.146   1.00 63.17  ? 358 LYS A N    1 
ATOM   1133  C  CA   . LYS A 1 151 ? 14.877  -8.509  9.999   1.00 63.63  ? 358 LYS A CA   1 
ATOM   1134  C  C    . LYS A 1 151 ? 15.284  -8.548  11.463  1.00 61.20  ? 358 LYS A C    1 
ATOM   1135  O  O    . LYS A 1 151 ? 14.563  -8.039  12.331  1.00 60.22  ? 358 LYS A O    1 
ATOM   1136  C  CB   . LYS A 1 151 ? 14.212  -9.831  9.581   1.00 66.56  ? 358 LYS A CB   1 
ATOM   1137  C  CG   . LYS A 1 151 ? 13.199  -10.404 10.575  1.00 68.59  ? 358 LYS A CG   1 
ATOM   1138  N  N    . ASN A 1 152 ? 16.434  -9.146  11.766  1.00 63.76  ? 359 ASN A N    1 
ATOM   1139  C  CA   . ASN A 1 152 ? 16.765  -9.426  13.154  1.00 56.08  ? 359 ASN A CA   1 
ATOM   1140  C  C    . ASN A 1 152 ? 18.273  -9.453  13.349  1.00 59.01  ? 359 ASN A C    1 
ATOM   1141  O  O    . ASN A 1 152 ? 19.070  -9.347  12.409  1.00 59.41  ? 359 ASN A O    1 
ATOM   1142  C  CB   . ASN A 1 152 ? 16.158  -10.753 13.602  1.00 54.54  ? 359 ASN A CB   1 
ATOM   1143  C  CG   . ASN A 1 152 ? 16.502  -11.882 12.663  1.00 59.29  ? 359 ASN A CG   1 
ATOM   1144  O  OD1  . ASN A 1 152 ? 17.607  -11.927 12.107  1.00 60.64  ? 359 ASN A OD1  1 
ATOM   1145  N  ND2  . ASN A 1 152 ? 15.561  -12.799 12.464  1.00 59.69  ? 359 ASN A ND2  1 
ATOM   1146  N  N    . ILE A 1 153 ? 18.650  -9.655  14.601  1.00 58.11  ? 360 ILE A N    1 
ATOM   1147  C  CA   . ILE A 1 153 ? 20.046  -9.654  14.967  1.00 56.30  ? 360 ILE A CA   1 
ATOM   1148  C  C    . ILE A 1 153 ? 20.783  -10.769 14.242  1.00 57.33  ? 360 ILE A C    1 
ATOM   1149  O  O    . ILE A 1 153 ? 21.962  -10.620 13.893  1.00 56.31  ? 360 ILE A O    1 
ATOM   1150  C  CB   . ILE A 1 153 ? 20.149  -9.764  16.501  1.00 56.17  ? 360 ILE A CB   1 
ATOM   1151  C  CG1  . ILE A 1 153 ? 21.393  -9.078  17.017  1.00 57.08  ? 360 ILE A CG1  1 
ATOM   1152  C  CG2  . ILE A 1 153 ? 20.189  -11.204 16.927  1.00 58.97  ? 360 ILE A CG2  1 
ATOM   1153  C  CD1  . ILE A 1 153 ? 21.588  -9.314  18.469  1.00 59.46  ? 360 ILE A CD1  1 
ATOM   1154  N  N    . PHE A 1 154 ? 20.107  -11.877 13.945  1.00 58.46  ? 361 PHE A N    1 
ATOM   1155  C  CA   . PHE A 1 154 ? 20.853  -13.019 13.367  1.00 51.50  ? 361 PHE A CA   1 
ATOM   1156  C  C    . PHE A 1 154 ? 21.223  -12.704 11.925  1.00 54.83  ? 361 PHE A C    1 
ATOM   1157  O  O    . PHE A 1 154 ? 22.365  -12.959 11.551  1.00 51.34  ? 361 PHE A O    1 
ATOM   1158  C  CB   . PHE A 1 154 ? 20.066  -14.325 13.462  1.00 57.73  ? 361 PHE A CB   1 
ATOM   1159  C  CG   . PHE A 1 154 ? 20.922  -15.550 13.280  1.00 56.75  ? 361 PHE A CG   1 
ATOM   1160  C  CD1  . PHE A 1 154 ? 21.659  -16.056 14.336  1.00 57.18  ? 361 PHE A CD1  1 
ATOM   1161  C  CD2  . PHE A 1 154 ? 21.021  -16.170 12.046  1.00 52.02  ? 361 PHE A CD2  1 
ATOM   1162  C  CE1  . PHE A 1 154 ? 22.456  -17.175 14.172  1.00 62.56  ? 361 PHE A CE1  1 
ATOM   1163  C  CE2  . PHE A 1 154 ? 21.830  -17.280 11.879  1.00 58.16  ? 361 PHE A CE2  1 
ATOM   1164  C  CZ   . PHE A 1 154 ? 22.549  -17.774 12.940  1.00 64.36  ? 361 PHE A CZ   1 
ATOM   1165  N  N    . GLU A 1 155 ? 20.277  -12.175 11.158  1.00 49.97  ? 362 GLU A N    1 
ATOM   1166  C  CA   . GLU A 1 155 ? 20.622  -11.790 9.795   1.00 47.06  ? 362 GLU A CA   1 
ATOM   1167  C  C    . GLU A 1 155 ? 21.713  -10.721 9.790   1.00 57.93  ? 362 GLU A C    1 
ATOM   1168  O  O    . GLU A 1 155 ? 22.554  -10.672 8.877   1.00 54.50  ? 362 GLU A O    1 
ATOM   1169  C  CB   . GLU A 1 155 ? 19.385  -11.267 9.063   1.00 55.26  ? 362 GLU A CB   1 
ATOM   1170  C  CG   . GLU A 1 155 ? 18.261  -12.273 8.825   1.00 59.70  ? 362 GLU A CG   1 
ATOM   1171  C  CD   . GLU A 1 155 ? 17.135  -11.697 7.946   1.00 66.23  ? 362 GLU A CD   1 
ATOM   1172  O  OE1  . GLU A 1 155 ? 17.306  -10.573 7.406   1.00 59.78  ? 362 GLU A OE1  1 
ATOM   1173  O  OE2  . GLU A 1 155 ? 16.090  -12.381 7.790   1.00 66.37  ? 362 GLU A OE2  1 
ATOM   1174  N  N    . SER A 1 156 ? 21.711  -9.855  10.800  1.00 55.52  ? 363 SER A N    1 
ATOM   1175  C  CA   . SER A 1 156 ? 22.682  -8.784  10.875  1.00 54.86  ? 363 SER A CA   1 
ATOM   1176  C  C    . SER A 1 156 ? 24.083  -9.282  11.233  1.00 51.71  ? 363 SER A C    1 
ATOM   1177  O  O    . SER A 1 156 ? 25.073  -8.609  10.907  1.00 47.80  ? 363 SER A O    1 
ATOM   1178  C  CB   . SER A 1 156 ? 22.199  -7.753  11.888  1.00 52.04  ? 363 SER A CB   1 
ATOM   1179  O  OG   . SER A 1 156 ? 23.165  -6.754  12.090  1.00 54.82  ? 363 SER A OG   1 
ATOM   1180  N  N    . PHE A 1 157 ? 24.201  -10.428 11.903  1.00 45.44  ? 364 PHE A N    1 
ATOM   1181  C  CA   . PHE A 1 157 ? 25.523  -11.034 12.009  1.00 47.84  ? 364 PHE A CA   1 
ATOM   1182  C  C    . PHE A 1 157 ? 25.907  -11.725 10.705  1.00 50.47  ? 364 PHE A C    1 
ATOM   1183  O  O    . PHE A 1 157 ? 27.068  -11.671 10.285  1.00 50.97  ? 364 PHE A O    1 
ATOM   1184  C  CB   . PHE A 1 157 ? 25.567  -12.021 13.161  1.00 48.87  ? 364 PHE A CB   1 
ATOM   1185  C  CG   . PHE A 1 157 ? 25.993  -11.417 14.463  1.00 49.92  ? 364 PHE A CG   1 
ATOM   1186  C  CD1  . PHE A 1 157 ? 27.320  -11.203 14.737  1.00 42.98  ? 364 PHE A CD1  1 
ATOM   1187  C  CD2  . PHE A 1 157 ? 25.054  -11.076 15.425  1.00 53.81  ? 364 PHE A CD2  1 
ATOM   1188  C  CE1  . PHE A 1 157 ? 27.706  -10.658 15.932  1.00 45.14  ? 364 PHE A CE1  1 
ATOM   1189  C  CE2  . PHE A 1 157 ? 25.435  -10.512 16.625  1.00 42.72  ? 364 PHE A CE2  1 
ATOM   1190  C  CZ   . PHE A 1 157 ? 26.748  -10.310 16.879  1.00 46.22  ? 364 PHE A CZ   1 
ATOM   1191  N  N    . VAL A 1 158 ? 24.938  -12.361 10.047  1.00 49.30  ? 365 VAL A N    1 
ATOM   1192  C  CA   . VAL A 1 158 ? 25.205  -13.026 8.781   1.00 44.58  ? 365 VAL A CA   1 
ATOM   1193  C  C    . VAL A 1 158 ? 25.757  -12.030 7.773   1.00 48.34  ? 365 VAL A C    1 
ATOM   1194  O  O    . VAL A 1 158 ? 26.758  -12.292 7.100   1.00 49.80  ? 365 VAL A O    1 
ATOM   1195  C  CB   . VAL A 1 158 ? 23.925  -13.708 8.271   1.00 52.12  ? 365 VAL A CB   1 
ATOM   1196  C  CG1  . VAL A 1 158 ? 24.049  -14.063 6.765   1.00 45.31  ? 365 VAL A CG1  1 
ATOM   1197  C  CG2  . VAL A 1 158 ? 23.623  -14.938 9.131   1.00 43.40  ? 365 VAL A CG2  1 
ATOM   1198  N  N    . ASP A 1 159 ? 25.116  -10.866 7.666   1.00 47.75  ? 366 ASP A N    1 
ATOM   1199  C  CA   . ASP A 1 159 ? 25.611  -9.798  6.808   1.00 48.15  ? 366 ASP A CA   1 
ATOM   1200  C  C    . ASP A 1 159 ? 27.000  -9.335  7.239   1.00 50.49  ? 366 ASP A C    1 
ATOM   1201  O  O    . ASP A 1 159 ? 27.887  -9.157  6.397   1.00 50.68  ? 366 ASP A O    1 
ATOM   1202  C  CB   . ASP A 1 159 ? 24.620  -8.631  6.815   1.00 48.19  ? 366 ASP A CB   1 
ATOM   1203  C  CG   . ASP A 1 159 ? 25.095  -7.433  6.002   1.00 59.07  ? 366 ASP A CG   1 
ATOM   1204  O  OD1  . ASP A 1 159 ? 24.794  -7.386  4.783   1.00 61.72  ? 366 ASP A OD1  1 
ATOM   1205  O  OD2  . ASP A 1 159 ? 25.744  -6.520  6.590   1.00 63.43  ? 366 ASP A OD2  1 
ATOM   1206  N  N    . TYR A 1 160 ? 27.216  -9.155  8.545   1.00 50.19  ? 367 TYR A N    1 
ATOM   1207  C  CA   . TYR A 1 160 ? 28.528  -8.736  9.037   1.00 44.38  ? 367 TYR A CA   1 
ATOM   1208  C  C    . TYR A 1 160 ? 29.635  -9.682  8.585   1.00 49.89  ? 367 TYR A C    1 
ATOM   1209  O  O    . TYR A 1 160 ? 30.727  -9.239  8.198   1.00 47.50  ? 367 TYR A O    1 
ATOM   1210  C  CB   . TYR A 1 160 ? 28.498  -8.651  10.553  1.00 43.02  ? 367 TYR A CB   1 
ATOM   1211  C  CG   . TYR A 1 160 ? 29.668  -7.945  11.193  1.00 46.15  ? 367 TYR A CG   1 
ATOM   1212  C  CD1  . TYR A 1 160 ? 30.880  -8.593  11.384  1.00 42.33  ? 367 TYR A CD1  1 
ATOM   1213  C  CD2  . TYR A 1 160 ? 29.536  -6.652  11.667  1.00 38.50  ? 367 TYR A CD2  1 
ATOM   1214  C  CE1  . TYR A 1 160 ? 31.929  -7.950  11.992  1.00 44.50  ? 367 TYR A CE1  1 
ATOM   1215  C  CE2  . TYR A 1 160 ? 30.573  -6.001  12.263  1.00 40.02  ? 367 TYR A CE2  1 
ATOM   1216  C  CZ   . TYR A 1 160 ? 31.767  -6.651  12.428  1.00 48.76  ? 367 TYR A CZ   1 
ATOM   1217  O  OH   . TYR A 1 160 ? 32.809  -5.981  13.028  1.00 51.41  ? 367 TYR A OH   1 
ATOM   1218  N  N    . VAL A 1 161 ? 29.375  -10.993 8.592   1.00 44.81  ? 368 VAL A N    1 
ATOM   1219  C  CA   . VAL A 1 161 ? 30.433  -11.927 8.207   1.00 49.50  ? 368 VAL A CA   1 
ATOM   1220  C  C    . VAL A 1 161 ? 30.437  -12.233 6.718   1.00 44.21  ? 368 VAL A C    1 
ATOM   1221  O  O    . VAL A 1 161 ? 31.330  -12.939 6.243   1.00 41.76  ? 368 VAL A O    1 
ATOM   1222  C  CB   . VAL A 1 161 ? 30.345  -13.233 9.016   1.00 46.51  ? 368 VAL A CB   1 
ATOM   1223  C  CG1  . VAL A 1 161 ? 30.482  -12.918 10.475  1.00 41.82  ? 368 VAL A CG1  1 
ATOM   1224  C  CG2  . VAL A 1 161 ? 29.055  -13.960 8.719   1.00 40.13  ? 368 VAL A CG2  1 
ATOM   1225  N  N    . ALA A 1 162 ? 29.501  -11.687 5.962   1.00 47.50  ? 369 ALA A N    1 
ATOM   1226  C  CA   . ALA A 1 162 ? 29.402  -12.021 4.554   1.00 45.91  ? 369 ALA A CA   1 
ATOM   1227  C  C    . ALA A 1 162 ? 30.592  -11.477 3.763   1.00 49.72  ? 369 ALA A C    1 
ATOM   1228  O  O    . ALA A 1 162 ? 31.158  -10.435 4.093   1.00 51.09  ? 369 ALA A O    1 
ATOM   1229  C  CB   . ALA A 1 162 ? 28.096  -11.467 4.002   1.00 45.24  ? 369 ALA A CB   1 
ATOM   1230  N  N    . VAL A 1 163 ? 30.967  -12.195 2.696   1.00 53.98  ? 370 VAL A N    1 
ATOM   1231  C  CA   . VAL A 1 163 ? 32.065  -11.766 1.825   1.00 50.08  ? 370 VAL A CA   1 
ATOM   1232  C  C    . VAL A 1 163 ? 31.640  -10.552 1.003   1.00 49.42  ? 370 VAL A C    1 
ATOM   1233  O  O    . VAL A 1 163 ? 30.513  -10.501 0.501   1.00 48.64  ? 370 VAL A O    1 
ATOM   1234  C  CB   . VAL A 1 163 ? 32.475  -12.932 0.905   1.00 52.77  ? 370 VAL A CB   1 
ATOM   1235  C  CG1  . VAL A 1 163 ? 33.472  -12.468 -0.183  1.00 53.33  ? 370 VAL A CG1  1 
ATOM   1236  C  CG2  . VAL A 1 163 ? 33.044  -14.080 1.726   1.00 46.13  ? 370 VAL A CG2  1 
ATOM   1237  N  N    . GLU A 1 164 ? 32.539  -9.565  0.861   1.00 51.17  ? 371 GLU A N    1 
ATOM   1238  C  CA   . GLU A 1 164 ? 32.328  -8.412  -0.017  1.00 50.22  ? 371 GLU A CA   1 
ATOM   1239  C  C    . GLU A 1 164 ? 33.373  -8.352  -1.118  1.00 51.34  ? 371 GLU A C    1 
ATOM   1240  O  O    . GLU A 1 164 ? 34.499  -8.828  -0.963  1.00 58.83  ? 371 GLU A O    1 
ATOM   1241  C  CB   . GLU A 1 164 ? 32.406  -7.051  0.700   1.00 52.22  ? 371 GLU A CB   1 
ATOM   1242  C  CG   . GLU A 1 164 ? 32.096  -7.002  2.164   1.00 52.99  ? 371 GLU A CG   1 
ATOM   1243  C  CD   . GLU A 1 164 ? 32.467  -5.657  2.749   1.00 52.76  ? 371 GLU A CD   1 
ATOM   1244  O  OE1  . GLU A 1 164 ? 31.897  -4.635  2.304   1.00 59.75  ? 371 GLU A OE1  1 
ATOM   1245  O  OE2  . GLU A 1 164 ? 33.312  -5.612  3.663   1.00 58.27  ? 371 GLU A OE2  1 
ATOM   1246  N  N    . GLN A 1 165 ? 33.017  -7.687  -2.213  1.00 51.41  ? 372 GLN A N    1 
ATOM   1247  C  CA   . GLN A 1 165 ? 33.947  -7.444  -3.303  1.00 48.73  ? 372 GLN A CA   1 
ATOM   1248  C  C    . GLN A 1 165 ? 34.632  -6.106  -3.092  1.00 56.94  ? 372 GLN A C    1 
ATOM   1249  O  O    . GLN A 1 165 ? 33.963  -5.071  -3.056  1.00 59.54  ? 372 GLN A O    1 
ATOM   1250  C  CB   . GLN A 1 165 ? 33.212  -7.460  -4.630  1.00 46.46  ? 372 GLN A CB   1 
ATOM   1251  C  CG   . GLN A 1 165 ? 32.353  -8.698  -4.750  1.00 51.47  ? 372 GLN A CG   1 
ATOM   1252  C  CD   . GLN A 1 165 ? 33.165  -9.969  -4.668  1.00 49.14  ? 372 GLN A CD   1 
ATOM   1253  O  OE1  . GLN A 1 165 ? 34.328  -10.018 -5.092  1.00 51.96  ? 372 GLN A OE1  1 
ATOM   1254  N  NE2  . GLN A 1 165 ? 32.566  -11.002 -4.124  1.00 49.58  ? 372 GLN A NE2  1 
ATOM   1255  N  N    . LEU A 1 166 ? 35.954  -6.123  -2.979  1.00 54.06  ? 373 LEU A N    1 
ATOM   1256  C  CA   . LEU A 1 166 ? 36.712  -4.859  -2.949  1.00 53.34  ? 373 LEU A CA   1 
ATOM   1257  C  C    . LEU A 1 166 ? 36.965  -4.543  -4.419  1.00 58.38  ? 373 LEU A C    1 
ATOM   1258  O  O    . LEU A 1 166 ? 37.970  -5.019  -4.951  1.00 61.77  ? 373 LEU A O    1 
ATOM   1259  C  CB   . LEU A 1 166 ? 38.000  -5.077  -2.161  1.00 55.40  ? 373 LEU A CB   1 
ATOM   1260  C  CG   . LEU A 1 166 ? 37.843  -5.125  -0.645  1.00 56.14  ? 373 LEU A CG   1 
ATOM   1261  C  CD1  . LEU A 1 166 ? 39.201  -5.213  0.025   1.00 48.30  ? 373 LEU A CD1  1 
ATOM   1262  C  CD2  . LEU A 1 166 ? 37.074  -3.918  -0.139  1.00 45.52  ? 373 LEU A CD2  1 
ATOM   1263  N  N    . ASP A 1 167 ? 36.074  -3.797  -5.062  1.00 61.33  ? 374 ASP A N    1 
ATOM   1264  C  CA   . ASP A 1 167 ? 36.231  -3.544  -6.517  1.00 57.24  ? 374 ASP A CA   1 
ATOM   1265  C  C    . ASP A 1 167 ? 36.060  -2.063  -6.841  1.00 57.61  ? 374 ASP A C    1 
ATOM   1266  O  O    . ASP A 1 167 ? 35.559  -1.320  -5.991  1.00 59.77  ? 374 ASP A O    1 
ATOM   1267  C  CB   . ASP A 1 167 ? 35.310  -4.432  -7.367  1.00 60.25  ? 374 ASP A CB   1 
ATOM   1268  C  CG   . ASP A 1 167 ? 33.825  -4.373  -7.063  1.00 58.34  ? 374 ASP A CG   1 
ATOM   1269  O  OD1  . ASP A 1 167 ? 33.433  -3.685  -6.104  1.00 63.31  ? 374 ASP A OD1  1 
ATOM   1270  O  OD2  . ASP A 1 167 ? 33.068  -5.032  -7.794  1.00 60.40  ? 374 ASP A OD2  1 
ATOM   1271  N  N    . GLY A 1 168 ? 36.465  -1.667  -8.040  1.00 58.60  ? 375 GLY A N    1 
ATOM   1272  C  CA   . GLY A 1 168 ? 36.310  -0.275  -8.510  1.00 60.72  ? 375 GLY A CA   1 
ATOM   1273  C  C    . GLY A 1 168 ? 37.088  0.749   -7.722  1.00 54.23  ? 375 GLY A C    1 
ATOM   1274  O  O    . GLY A 1 168 ? 38.318  0.660   -7.711  1.00 59.16  ? 375 GLY A O    1 
ATOM   1275  N  N    . ASP A 1 169 ? 36.389  1.723   -7.136  1.00 53.47  ? 376 ASP A N    1 
ATOM   1276  C  CA   . ASP A 1 169 ? 37.050  2.770   -6.312  1.00 50.39  ? 376 ASP A CA   1 
ATOM   1277  C  C    . ASP A 1 169 ? 37.490  2.152   -4.989  1.00 48.41  ? 376 ASP A C    1 
ATOM   1278  O  O    . ASP A 1 169 ? 38.205  2.817   -4.250  1.00 48.30  ? 376 ASP A O    1 
ATOM   1279  C  CB   . ASP A 1 169 ? 36.142  3.984   -6.104  1.00 53.65  ? 376 ASP A CB   1 
ATOM   1280  C  CG   . ASP A 1 169 ? 36.861  5.309   -5.954  1.00 48.08  ? 376 ASP A CG   1 
ATOM   1281  O  OD1  . ASP A 1 169 ? 38.038  5.384   -6.330  1.00 52.88  ? 376 ASP A OD1  1 
ATOM   1282  O  OD2  . ASP A 1 169 ? 36.228  6.255   -5.466  1.00 49.09  ? 376 ASP A OD2  1 
ATOM   1283  N  N    . ASN A 1 170 ? 37.091  0.912   -4.736  1.00 50.13  ? 377 ASN A N    1 
ATOM   1284  C  CA   . ASN A 1 170 ? 37.433  0.224   -3.472  1.00 54.63  ? 377 ASN A CA   1 
ATOM   1285  C  C    . ASN A 1 170 ? 38.293  -1.009  -3.774  1.00 53.03  ? 377 ASN A C    1 
ATOM   1286  O  O    . ASN A 1 170 ? 38.241  -1.946  -2.993  1.00 52.50  ? 377 ASN A O    1 
ATOM   1287  C  CB   . ASN A 1 170 ? 36.160  -0.047  -2.674  1.00 47.72  ? 377 ASN A CB   1 
ATOM   1288  C  CG   . ASN A 1 170 ? 35.382  1.215   -2.393  1.00 52.84  ? 377 ASN A CG   1 
ATOM   1289  O  OD1  . ASN A 1 170 ? 35.882  2.100   -1.716  1.00 51.26  ? 377 ASN A OD1  1 
ATOM   1290  N  ND2  . ASN A 1 170 ? 34.179  1.317   -2.926  1.00 45.38  ? 377 ASN A ND2  1 
ATOM   1291  N  N    . LYS A 1 171 ? 39.089  -0.973  -4.840  1.00 52.53  ? 378 LYS A N    1 
ATOM   1292  C  CA   . LYS A 1 171 ? 40.025  -2.082  -5.160  1.00 53.80  ? 378 LYS A CA   1 
ATOM   1293  C  C    . LYS A 1 171 ? 41.087  -2.195  -4.066  1.00 50.18  ? 378 LYS A C    1 
ATOM   1294  O  O    . LYS A 1 171 ? 41.417  -1.176  -3.454  1.00 47.13  ? 378 LYS A O    1 
ATOM   1295  C  CB   . LYS A 1 171 ? 40.685  -1.854  -6.520  1.00 48.90  ? 378 LYS A CB   1 
ATOM   1296  C  CG   . LYS A 1 171 ? 39.985  -2.504  -7.703  1.00 56.05  ? 378 LYS A CG   1 
ATOM   1297  C  CD   . LYS A 1 171 ? 40.583  -2.113  -9.033  1.00 55.98  ? 378 LYS A CD   1 
ATOM   1298  N  N    . TYR A 1 172 ? 41.619  -3.386  -3.846  1.00 51.81  ? 379 TYR A N    1 
ATOM   1299  C  CA   . TYR A 1 172 ? 42.583  -3.578  -2.738  1.00 57.05  ? 379 TYR A CA   1 
ATOM   1300  C  C    . TYR A 1 172 ? 44.002  -3.236  -3.195  1.00 53.65  ? 379 TYR A C    1 
ATOM   1301  O  O    . TYR A 1 172 ? 44.396  -3.622  -4.288  1.00 54.62  ? 379 TYR A O    1 
ATOM   1302  C  CB   . TYR A 1 172 ? 42.461  -5.004  -2.200  1.00 53.54  ? 379 TYR A CB   1 
ATOM   1303  C  CG   . TYR A 1 172 ? 43.578  -5.469  -1.307  1.00 47.63  ? 379 TYR A CG   1 
ATOM   1304  C  CD1  . TYR A 1 172 ? 43.824  -4.870  -0.083  1.00 45.92  ? 379 TYR A CD1  1 
ATOM   1305  C  CD2  . TYR A 1 172 ? 44.376  -6.527  -1.688  1.00 48.51  ? 379 TYR A CD2  1 
ATOM   1306  C  CE1  . TYR A 1 172 ? 44.854  -5.303  0.731   1.00 52.37  ? 379 TYR A CE1  1 
ATOM   1307  C  CE2  . TYR A 1 172 ? 45.402  -6.979  -0.882  1.00 51.10  ? 379 TYR A CE2  1 
ATOM   1308  C  CZ   . TYR A 1 172 ? 45.643  -6.362  0.327   1.00 53.94  ? 379 TYR A CZ   1 
ATOM   1309  O  OH   . TYR A 1 172 ? 46.663  -6.820  1.097   1.00 45.08  ? 379 TYR A OH   1 
ATOM   1310  N  N    . ASP A 1 173 ? 44.741  -2.538  -2.342  1.00 48.68  ? 380 ASP A N    1 
ATOM   1311  C  CA   . ASP A 1 173 ? 46.133  -2.217  -2.663  1.00 55.33  ? 380 ASP A CA   1 
ATOM   1312  C  C    . ASP A 1 173 ? 47.007  -3.431  -2.368  1.00 56.45  ? 380 ASP A C    1 
ATOM   1313  O  O    . ASP A 1 173 ? 47.590  -3.557  -1.286  1.00 55.41  ? 380 ASP A O    1 
ATOM   1314  C  CB   . ASP A 1 173 ? 46.618  -1.005  -1.878  1.00 54.94  ? 380 ASP A CB   1 
ATOM   1315  C  CG   . ASP A 1 173 ? 48.114  -0.766  -2.059  1.00 57.00  ? 380 ASP A CG   1 
ATOM   1316  O  OD1  . ASP A 1 173 ? 48.636  -1.115  -3.143  1.00 57.67  ? 380 ASP A OD1  1 
ATOM   1317  O  OD2  . ASP A 1 173 ? 48.762  -0.241  -1.123  1.00 57.38  ? 380 ASP A OD2  1 
ATOM   1318  N  N    . ALA A 1 174 ? 47.146  -4.309  -3.361  1.00 54.61  ? 381 ALA A N    1 
ATOM   1319  C  CA   . ALA A 1 174 ? 47.832  -5.593  -3.195  1.00 53.56  ? 381 ALA A CA   1 
ATOM   1320  C  C    . ALA A 1 174 ? 49.326  -5.536  -3.490  1.00 54.50  ? 381 ALA A C    1 
ATOM   1321  O  O    . ALA A 1 174 ? 49.853  -6.462  -4.097  1.00 65.07  ? 381 ALA A O    1 
ATOM   1322  C  CB   . ALA A 1 174 ? 47.158  -6.647  -4.067  1.00 53.01  ? 381 ALA A CB   1 
ATOM   1323  N  N    . GLY A 1 175 ? 50.043  -4.491  -3.097  1.00 55.45  ? 382 GLY A N    1 
ATOM   1324  C  CA   . GLY A 1 175 ? 51.499  -4.577  -3.058  1.00 54.64  ? 382 GLY A CA   1 
ATOM   1325  C  C    . GLY A 1 175 ? 52.129  -4.480  -4.435  1.00 64.97  ? 382 GLY A C    1 
ATOM   1326  O  O    . GLY A 1 175 ? 51.764  -3.612  -5.237  1.00 64.86  ? 382 GLY A O    1 
ATOM   1327  N  N    . GLU A 1 176 ? 53.037  -5.401  -4.740  1.00 63.61  ? 383 GLU A N    1 
ATOM   1328  C  CA   . GLU A 1 176 ? 53.713  -5.407  -6.062  1.00 65.91  ? 383 GLU A CA   1 
ATOM   1329  C  C    . GLU A 1 176 ? 52.694  -5.578  -7.190  1.00 67.48  ? 383 GLU A C    1 
ATOM   1330  O  O    . GLU A 1 176 ? 53.075  -5.366  -8.347  1.00 70.07  ? 383 GLU A O    1 
ATOM   1331  C  CB   . GLU A 1 176 ? 54.751  -6.525  -6.117  1.00 65.64  ? 383 GLU A CB   1 
ATOM   1332  C  CG   . GLU A 1 176 ? 54.161  -7.921  -6.133  1.00 73.95  ? 383 GLU A CG   1 
ATOM   1333  C  CD   . GLU A 1 176 ? 54.722  -8.816  -7.223  1.00 80.62  ? 383 GLU A CD   1 
ATOM   1334  O  OE1  . GLU A 1 176 ? 54.279  -8.688  -8.378  1.00 80.57  ? 383 GLU A OE1  1 
ATOM   1335  O  OE2  . GLU A 1 176 ? 55.602  -9.637  -6.912  1.00 86.31  ? 383 GLU A OE2  1 
ATOM   1336  N  N    . HIS A 1 177 ? 51.454  -5.935  -6.863  1.00 63.66  ? 384 HIS A N    1 
ATOM   1337  C  CA   . HIS A 1 177 ? 50.438  -6.181  -7.912  1.00 61.98  ? 384 HIS A CA   1 
ATOM   1338  C  C    . HIS A 1 177 ? 49.557  -4.945  -8.052  1.00 59.93  ? 384 HIS A C    1 
ATOM   1339  O  O    . HIS A 1 177 ? 48.624  -4.980  -8.858  1.00 59.35  ? 384 HIS A O    1 
ATOM   1340  C  CB   . HIS A 1 177 ? 49.625  -7.432  -7.589  1.00 64.66  ? 384 HIS A CB   1 
ATOM   1341  C  CG   . HIS A 1 177 ? 50.413  -8.693  -7.532  1.00 68.97  ? 384 HIS A CG   1 
ATOM   1342  N  ND1  . HIS A 1 177 ? 50.663  -9.346  -6.347  1.00 68.23  ? 384 HIS A ND1  1 
ATOM   1343  C  CD2  . HIS A 1 177 ? 50.979  -9.437  -8.503  1.00 67.48  ? 384 HIS A CD2  1 
ATOM   1344  C  CE1  . HIS A 1 177 ? 51.357  -10.437 -6.587  1.00 70.97  ? 384 HIS A CE1  1 
ATOM   1345  N  NE2  . HIS A 1 177 ? 51.563  -10.515 -7.902  1.00 70.28  ? 384 HIS A NE2  1 
ATOM   1346  N  N    . GLY A 1 178 ? 49.861  -3.895  -7.296  1.00 56.59  ? 385 GLY A N    1 
ATOM   1347  C  CA   . GLY A 1 178 ? 49.066  -2.657  -7.352  1.00 56.10  ? 385 GLY A CA   1 
ATOM   1348  C  C    . GLY A 1 178 ? 47.605  -2.915  -7.067  1.00 60.81  ? 385 GLY A C    1 
ATOM   1349  O  O    . GLY A 1 178 ? 47.299  -3.969  -6.505  1.00 56.74  ? 385 GLY A O    1 
ATOM   1350  N  N    . LEU A 1 179 ? 46.730  -1.992  -7.460  1.00 57.98  ? 386 LEU A N    1 
ATOM   1351  C  CA   . LEU A 1 179 ? 45.328  -2.158  -7.119  1.00 51.36  ? 386 LEU A CA   1 
ATOM   1352  C  C    . LEU A 1 179 ? 44.757  -3.386  -7.814  1.00 59.62  ? 386 LEU A C    1 
ATOM   1353  O  O    . LEU A 1 179 ? 45.066  -3.674  -8.973  1.00 65.59  ? 386 LEU A O    1 
ATOM   1354  C  CB   . LEU A 1 179 ? 44.535  -0.906  -7.488  1.00 50.49  ? 386 LEU A CB   1 
ATOM   1355  C  CG   . LEU A 1 179 ? 44.997  0.371   -6.781  1.00 51.21  ? 386 LEU A CG   1 
ATOM   1356  C  CD1  . LEU A 1 179 ? 44.196  1.606   -7.237  1.00 53.72  ? 386 LEU A CD1  1 
ATOM   1357  C  CD2  . LEU A 1 179 ? 44.911  0.208   -5.281  1.00 51.43  ? 386 LEU A CD2  1 
ATOM   1358  N  N    . GLN A 1 180 ? 43.916  -4.116  -7.096  1.00 57.00  ? 387 GLN A N    1 
ATOM   1359  C  CA   . GLN A 1 180 ? 43.449  -5.405  -7.567  1.00 55.84  ? 387 GLN A CA   1 
ATOM   1360  C  C    . GLN A 1 180 ? 42.046  -5.620  -7.038  1.00 53.29  ? 387 GLN A C    1 
ATOM   1361  O  O    . GLN A 1 180 ? 41.749  -5.253  -5.902  1.00 56.59  ? 387 GLN A O    1 
ATOM   1362  C  CB   . GLN A 1 180 ? 44.373  -6.532  -7.080  1.00 58.68  ? 387 GLN A CB   1 
ATOM   1363  C  CG   . GLN A 1 180 ? 45.713  -6.602  -7.809  1.00 61.49  ? 387 GLN A CG   1 
ATOM   1364  C  CD   . GLN A 1 180 ? 45.567  -7.179  -9.201  1.00 55.43  ? 387 GLN A CD   1 
ATOM   1365  O  OE1  . GLN A 1 180 ? 44.572  -7.817  -9.520  1.00 57.68  ? 387 GLN A OE1  1 
ATOM   1366  N  NE2  . GLN A 1 180 ? 46.556  -6.958  -10.026 1.00 58.49  ? 387 GLN A NE2  1 
ATOM   1367  N  N    . GLU A 1 181 ? 41.190  -6.201  -7.859  1.00 50.13  ? 388 GLU A N    1 
ATOM   1368  C  CA   . GLU A 1 181 ? 39.922  -6.671  -7.341  1.00 49.59  ? 388 GLU A CA   1 
ATOM   1369  C  C    . GLU A 1 181 ? 40.190  -7.751  -6.300  1.00 57.55  ? 388 GLU A C    1 
ATOM   1370  O  O    . GLU A 1 181 ? 41.137  -8.531  -6.423  1.00 54.61  ? 388 GLU A O    1 
ATOM   1371  C  CB   . GLU A 1 181 ? 39.053  -7.188  -8.490  1.00 51.34  ? 388 GLU A CB   1 
ATOM   1372  C  CG   . GLU A 1 181 ? 38.763  -6.101  -9.535  1.00 60.16  ? 388 GLU A CG   1 
ATOM   1373  C  CD   . GLU A 1 181 ? 37.895  -6.572  -10.707 1.00 75.21  ? 388 GLU A CD   1 
ATOM   1374  O  OE1  . GLU A 1 181 ? 37.161  -7.588  -10.566 1.00 72.71  ? 388 GLU A OE1  1 
ATOM   1375  O  OE2  . GLU A 1 181 ? 37.934  -5.903  -11.770 1.00 75.69  ? 388 GLU A OE2  1 
ATOM   1376  N  N    . ALA A 1 182 ? 39.381  -7.775  -5.244  1.00 57.49  ? 389 ALA A N    1 
ATOM   1377  C  CA   . ALA A 1 182 ? 39.625  -8.724  -4.171  1.00 52.86  ? 389 ALA A CA   1 
ATOM   1378  C  C    . ALA A 1 182 ? 38.329  -8.969  -3.422  1.00 52.56  ? 389 ALA A C    1 
ATOM   1379  O  O    . ALA A 1 182 ? 37.374  -8.206  -3.534  1.00 59.60  ? 389 ALA A O    1 
ATOM   1380  C  CB   . ALA A 1 182 ? 40.706  -8.218  -3.219  1.00 51.09  ? 389 ALA A CB   1 
ATOM   1381  N  N    . GLU A 1 183 ? 38.313  -10.045 -2.644  1.00 53.26  ? 390 GLU A N    1 
ATOM   1382  C  CA   . GLU A 1 183 ? 37.236  -10.309 -1.707  1.00 53.19  ? 390 GLU A CA   1 
ATOM   1383  C  C    . GLU A 1 183 ? 37.736  -10.040 -0.305  1.00 53.33  ? 390 GLU A C    1 
ATOM   1384  O  O    . GLU A 1 183 ? 38.888  -10.343 0.014   1.00 59.03  ? 390 GLU A O    1 
ATOM   1385  C  CB   . GLU A 1 183 ? 36.751  -11.741 -1.809  1.00 50.34  ? 390 GLU A CB   1 
ATOM   1386  C  CG   . GLU A 1 183 ? 36.354  -12.119 -3.203  1.00 54.39  ? 390 GLU A CG   1 
ATOM   1387  C  CD   . GLU A 1 183 ? 35.493  -13.343 -3.205  1.00 61.31  ? 390 GLU A CD   1 
ATOM   1388  O  OE1  . GLU A 1 183 ? 35.632  -14.161 -2.255  1.00 68.96  ? 390 GLU A OE1  1 
ATOM   1389  O  OE2  . GLU A 1 183 ? 34.677  -13.475 -4.138  1.00 57.53  ? 390 GLU A OE2  1 
ATOM   1390  N  N    . LYS A 1 184 ? 36.870  -9.477  0.524   1.00 49.08  ? 391 LYS A N    1 
ATOM   1391  C  CA   . LYS A 1 184 ? 37.168  -9.238  1.926   1.00 48.65  ? 391 LYS A CA   1 
ATOM   1392  C  C    . LYS A 1 184 ? 36.103  -9.920  2.760   1.00 51.86  ? 391 LYS A C    1 
ATOM   1393  O  O    . LYS A 1 184 ? 34.907  -9.855  2.438   1.00 53.46  ? 391 LYS A O    1 
ATOM   1394  C  CB   . LYS A 1 184 ? 37.211  -7.749  2.262   1.00 49.53  ? 391 LYS A CB   1 
ATOM   1395  C  CG   . LYS A 1 184 ? 37.318  -7.437  3.754   1.00 49.16  ? 391 LYS A CG   1 
ATOM   1396  C  CD   . LYS A 1 184 ? 37.520  -5.932  3.975   1.00 48.70  ? 391 LYS A CD   1 
ATOM   1397  C  CE   . LYS A 1 184 ? 37.670  -5.549  5.444   1.00 49.32  ? 391 LYS A CE   1 
ATOM   1398  N  NZ   . LYS A 1 184 ? 36.341  -5.264  6.084   1.00 54.56  ? 391 LYS A NZ   1 
ATOM   1399  N  N    . GLY A 1 185 ? 36.545  -10.586 3.818   1.00 50.15  ? 392 GLY A N    1 
ATOM   1400  C  CA   . GLY A 1 185 ? 35.644  -11.259 4.722   1.00 45.58  ? 392 GLY A CA   1 
ATOM   1401  C  C    . GLY A 1 185 ? 36.086  -11.125 6.159   1.00 48.59  ? 392 GLY A C    1 
ATOM   1402  O  O    . GLY A 1 185 ? 37.279  -11.166 6.471   1.00 48.20  ? 392 GLY A O    1 
ATOM   1403  N  N    . VAL A 1 186 ? 35.127  -10.968 7.052   1.00 46.51  ? 393 VAL A N    1 
ATOM   1404  C  CA   . VAL A 1 186 ? 35.420  -10.743 8.454   1.00 50.54  ? 393 VAL A CA   1 
ATOM   1405  C  C    . VAL A 1 186 ? 34.832  -11.889 9.263   1.00 46.79  ? 393 VAL A C    1 
ATOM   1406  O  O    . VAL A 1 186 ? 33.774  -12.427 8.921   1.00 47.26  ? 393 VAL A O    1 
ATOM   1407  C  CB   . VAL A 1 186 ? 34.876  -9.374  8.911   1.00 52.15  ? 393 VAL A CB   1 
ATOM   1408  C  CG1  . VAL A 1 186 ? 34.797  -9.299  10.414  1.00 45.45  ? 393 VAL A CG1  1 
ATOM   1409  C  CG2  . VAL A 1 186 ? 35.761  -8.260  8.371   1.00 42.67  ? 393 VAL A CG2  1 
ATOM   1410  N  N    . LYS A 1 187 ? 35.553  -12.302 10.300  1.00 49.32  ? 394 LYS A N    1 
ATOM   1411  C  CA   . LYS A 1 187 ? 35.042  -13.277 11.249  1.00 50.24  ? 394 LYS A CA   1 
ATOM   1412  C  C    . LYS A 1 187 ? 35.502  -12.865 12.630  1.00 47.05  ? 394 LYS A C    1 
ATOM   1413  O  O    . LYS A 1 187 ? 36.408  -12.041 12.783  1.00 49.70  ? 394 LYS A O    1 
ATOM   1414  C  CB   . LYS A 1 187 ? 35.497  -14.710 10.931  1.00 51.18  ? 394 LYS A CB   1 
ATOM   1415  C  CG   . LYS A 1 187 ? 34.692  -15.372 9.799   1.00 51.26  ? 394 LYS A CG   1 
ATOM   1416  C  CD   . LYS A 1 187 ? 33.603  -16.299 10.326  1.00 55.46  ? 394 LYS A CD   1 
ATOM   1417  C  CE   . LYS A 1 187 ? 32.901  -17.081 9.196   1.00 59.74  ? 394 LYS A CE   1 
ATOM   1418  N  NZ   . LYS A 1 187 ? 33.845  -17.916 8.379   1.00 67.52  ? 394 LYS A NZ   1 
ATOM   1419  N  N    . PHE A 1 188 ? 34.848  -13.430 13.639  1.00 48.23  ? 395 PHE A N    1 
ATOM   1420  C  CA   . PHE A 1 188 ? 35.238  -13.211 15.026  1.00 45.98  ? 395 PHE A CA   1 
ATOM   1421  C  C    . PHE A 1 188 ? 36.189  -14.303 15.490  1.00 44.78  ? 395 PHE A C    1 
ATOM   1422  O  O    . PHE A 1 188 ? 35.894  -15.494 15.336  1.00 46.61  ? 395 PHE A O    1 
ATOM   1423  C  CB   . PHE A 1 188 ? 33.999  -13.164 15.912  1.00 47.92  ? 395 PHE A CB   1 
ATOM   1424  C  CG   . PHE A 1 188 ? 33.170  -11.965 15.649  1.00 50.37  ? 395 PHE A CG   1 
ATOM   1425  C  CD1  . PHE A 1 188 ? 33.516  -10.743 16.205  1.00 45.31  ? 395 PHE A CD1  1 
ATOM   1426  C  CD2  . PHE A 1 188 ? 32.098  -12.029 14.772  1.00 45.97  ? 395 PHE A CD2  1 
ATOM   1427  C  CE1  . PHE A 1 188 ? 32.768  -9.603  15.915  1.00 52.66  ? 395 PHE A CE1  1 
ATOM   1428  C  CE2  . PHE A 1 188 ? 31.351  -10.898 14.476  1.00 48.86  ? 395 PHE A CE2  1 
ATOM   1429  C  CZ   . PHE A 1 188 ? 31.685  -9.678  15.041  1.00 46.77  ? 395 PHE A CZ   1 
ATOM   1430  N  N    . LEU A 1 189 ? 37.328  -13.895 16.059  1.00 41.33  ? 396 LEU A N    1 
ATOM   1431  C  CA   . LEU A 1 189 ? 38.216  -14.880 16.669  1.00 48.44  ? 396 LEU A CA   1 
ATOM   1432  C  C    . LEU A 1 189 ? 37.737  -15.253 18.067  1.00 51.88  ? 396 LEU A C    1 
ATOM   1433  O  O    . LEU A 1 189 ? 37.700  -16.438 18.421  1.00 53.60  ? 396 LEU A O    1 
ATOM   1434  C  CB   . LEU A 1 189 ? 39.653  -14.364 16.709  1.00 47.07  ? 396 LEU A CB   1 
ATOM   1435  C  CG   . LEU A 1 189 ? 40.294  -14.297 15.317  1.00 50.36  ? 396 LEU A CG   1 
ATOM   1436  C  CD1  . LEU A 1 189 ? 41.613  -13.540 15.363  1.00 44.04  ? 396 LEU A CD1  1 
ATOM   1437  C  CD2  . LEU A 1 189 ? 40.457  -15.698 14.741  1.00 44.42  ? 396 LEU A CD2  1 
ATOM   1438  N  N    . THR A 1 190 ? 37.356  -14.248 18.860  1.00 48.14  ? 397 THR A N    1 
ATOM   1439  C  CA   . THR A 1 190 ? 36.776  -14.412 20.186  1.00 44.86  ? 397 THR A CA   1 
ATOM   1440  C  C    . THR A 1 190 ? 35.601  -13.453 20.337  1.00 49.00  ? 397 THR A C    1 
ATOM   1441  O  O    . THR A 1 190 ? 35.474  -12.472 19.600  1.00 52.15  ? 397 THR A O    1 
ATOM   1442  C  CB   . THR A 1 190 ? 37.776  -14.105 21.307  1.00 46.35  ? 397 THR A CB   1 
ATOM   1443  O  OG1  . THR A 1 190 ? 38.175  -12.728 21.214  1.00 45.08  ? 397 THR A OG1  1 
ATOM   1444  C  CG2  . THR A 1 190 ? 38.994  -14.990 21.228  1.00 37.38  ? 397 THR A CG2  1 
ATOM   1445  N  N    . LEU A 1 191 ? 34.753  -13.743 21.325  1.00 46.95  ? 398 LEU A N    1 
ATOM   1446  C  CA   . LEU A 1 191 ? 33.665  -12.874 21.749  1.00 42.69  ? 398 LEU A CA   1 
ATOM   1447  C  C    . LEU A 1 191 ? 33.776  -12.653 23.253  1.00 42.03  ? 398 LEU A C    1 
ATOM   1448  O  O    . LEU A 1 191 ? 33.943  -13.633 24.011  1.00 45.91  ? 398 LEU A O    1 
ATOM   1449  C  CB   . LEU A 1 191 ? 32.320  -13.490 21.379  1.00 44.95  ? 398 LEU A CB   1 
ATOM   1450  C  CG   . LEU A 1 191 ? 32.008  -13.434 19.870  1.00 46.75  ? 398 LEU A CG   1 
ATOM   1451  C  CD1  . LEU A 1 191 ? 30.995  -14.484 19.473  1.00 46.13  ? 398 LEU A CD1  1 
ATOM   1452  C  CD2  . LEU A 1 191 ? 31.526  -12.048 19.434  1.00 42.06  ? 398 LEU A CD2  1 
ATOM   1453  N  N    . PRO A 1 192 ? 33.714  -11.407 23.726  1.00 41.71  ? 399 PRO A N    1 
ATOM   1454  C  CA   . PRO A 1 192 ? 34.011  -11.122 25.139  1.00 43.30  ? 399 PRO A CA   1 
ATOM   1455  C  C    . PRO A 1 192 ? 32.881  -11.579 26.043  1.00 45.93  ? 399 PRO A C    1 
ATOM   1456  O  O    . PRO A 1 192 ? 31.774  -11.875 25.564  1.00 41.18  ? 399 PRO A O    1 
ATOM   1457  C  CB   . PRO A 1 192 ? 34.163  -9.594  25.164  1.00 43.29  ? 399 PRO A CB   1 
ATOM   1458  C  CG   . PRO A 1 192 ? 33.275  -9.133  24.092  1.00 45.07  ? 399 PRO A CG   1 
ATOM   1459  C  CD   . PRO A 1 192 ? 33.370  -10.178 22.991  1.00 43.73  ? 399 PRO A CD   1 
ATOM   1460  N  N    . PRO A 1 193 ? 33.129  -11.680 27.357  1.00 45.31  ? 400 PRO A N    1 
ATOM   1461  C  CA   . PRO A 1 193 ? 32.060  -12.122 28.267  1.00 40.81  ? 400 PRO A CA   1 
ATOM   1462  C  C    . PRO A 1 193 ? 30.898  -11.163 28.315  1.00 45.97  ? 400 PRO A C    1 
ATOM   1463  O  O    . PRO A 1 193 ? 29.761  -11.588 28.545  1.00 47.03  ? 400 PRO A O    1 
ATOM   1464  C  CB   . PRO A 1 193 ? 32.769  -12.208 29.627  1.00 42.17  ? 400 PRO A CB   1 
ATOM   1465  C  CG   . PRO A 1 193 ? 34.218  -12.395 29.291  1.00 49.52  ? 400 PRO A CG   1 
ATOM   1466  C  CD   . PRO A 1 193 ? 34.420  -11.552 28.054  1.00 47.23  ? 400 PRO A CD   1 
ATOM   1467  N  N    . VAL A 1 194 ? 31.152  -9.876  28.139  1.00 45.51  ? 401 VAL A N    1 
ATOM   1468  C  CA   . VAL A 1 194 ? 30.103  -8.878  28.058  1.00 42.30  ? 401 VAL A CA   1 
ATOM   1469  C  C    . VAL A 1 194 ? 30.163  -8.307  26.653  1.00 46.49  ? 401 VAL A C    1 
ATOM   1470  O  O    . VAL A 1 194 ? 31.208  -7.793  26.235  1.00 52.09  ? 401 VAL A O    1 
ATOM   1471  C  CB   . VAL A 1 194 ? 30.277  -7.787  29.123  1.00 48.26  ? 401 VAL A CB   1 
ATOM   1472  C  CG1  . VAL A 1 194 ? 29.024  -6.944  29.236  1.00 45.69  ? 401 VAL A CG1  1 
ATOM   1473  C  CG2  . VAL A 1 194 ? 30.617  -8.411  30.454  1.00 45.91  ? 401 VAL A CG2  1 
ATOM   1474  N  N    . LEU A 1 195 ? 29.064  -8.437  25.914  1.00 47.85  ? 402 LEU A N    1 
ATOM   1475  C  CA   . LEU A 1 195 ? 28.976  -8.049  24.516  1.00 44.14  ? 402 LEU A CA   1 
ATOM   1476  C  C    . LEU A 1 195 ? 28.140  -6.797  24.394  1.00 48.15  ? 402 LEU A C    1 
ATOM   1477  O  O    . LEU A 1 195 ? 26.955  -6.813  24.742  1.00 54.66  ? 402 LEU A O    1 
ATOM   1478  C  CB   . LEU A 1 195 ? 28.317  -9.133  23.679  1.00 47.89  ? 402 LEU A CB   1 
ATOM   1479  C  CG   . LEU A 1 195 ? 29.144  -9.907  22.680  1.00 53.20  ? 402 LEU A CG   1 
ATOM   1480  C  CD1  . LEU A 1 195 ? 28.166  -10.543 21.758  1.00 52.17  ? 402 LEU A CD1  1 
ATOM   1481  C  CD2  . LEU A 1 195 ? 30.102  -9.023  21.917  1.00 46.13  ? 402 LEU A CD2  1 
ATOM   1482  N  N    . HIS A 1 196 ? 28.732  -5.742  23.844  1.00 45.18  ? 403 HIS A N    1 
ATOM   1483  C  CA   . HIS A 1 196 ? 28.054  -4.474  23.612  1.00 40.17  ? 403 HIS A CA   1 
ATOM   1484  C  C    . HIS A 1 196 ? 27.777  -4.366  22.122  1.00 43.73  ? 403 HIS A C    1 
ATOM   1485  O  O    . HIS A 1 196 ? 28.709  -4.239  21.322  1.00 47.33  ? 403 HIS A O    1 
ATOM   1486  C  CB   . HIS A 1 196 ? 28.899  -3.297  24.101  1.00 35.65  ? 403 HIS A CB   1 
ATOM   1487  C  CG   . HIS A 1 196 ? 28.806  -3.065  25.569  1.00 42.98  ? 403 HIS A CG   1 
ATOM   1488  N  ND1  . HIS A 1 196 ? 29.175  -1.880  26.164  1.00 52.27  ? 403 HIS A ND1  1 
ATOM   1489  C  CD2  . HIS A 1 196 ? 28.396  -3.878  26.573  1.00 51.23  ? 403 HIS A CD2  1 
ATOM   1490  C  CE1  . HIS A 1 196 ? 28.984  -1.968  27.469  1.00 45.50  ? 403 HIS A CE1  1 
ATOM   1491  N  NE2  . HIS A 1 196 ? 28.512  -3.171  27.742  1.00 43.06  ? 403 HIS A NE2  1 
ATOM   1492  N  N    . LEU A 1 197 ? 26.497  -4.395  21.760  1.00 42.20  ? 404 LEU A N    1 
ATOM   1493  C  CA   . LEU A 1 197 ? 26.051  -4.225  20.388  1.00 42.46  ? 404 LEU A CA   1 
ATOM   1494  C  C    . LEU A 1 197 ? 25.461  -2.831  20.194  1.00 48.56  ? 404 LEU A C    1 
ATOM   1495  O  O    . LEU A 1 197 ? 24.549  -2.412  20.930  1.00 42.47  ? 404 LEU A O    1 
ATOM   1496  C  CB   . LEU A 1 197 ? 25.017  -5.294  20.020  1.00 44.71  ? 404 LEU A CB   1 
ATOM   1497  C  CG   . LEU A 1 197 ? 25.506  -6.698  20.377  1.00 49.16  ? 404 LEU A CG   1 
ATOM   1498  C  CD1  . LEU A 1 197 ? 24.455  -7.786  20.121  1.00 45.90  ? 404 LEU A CD1  1 
ATOM   1499  C  CD2  . LEU A 1 197 ? 26.813  -6.989  19.641  1.00 41.54  ? 404 LEU A CD2  1 
ATOM   1500  N  N    . GLN A 1 198 ? 25.969  -2.123  19.192  1.00 43.16  ? 405 GLN A N    1 
ATOM   1501  C  CA   . GLN A 1 198 ? 25.418  -0.835  18.809  1.00 44.48  ? 405 GLN A CA   1 
ATOM   1502  C  C    . GLN A 1 198 ? 24.636  -1.019  17.513  1.00 48.27  ? 405 GLN A C    1 
ATOM   1503  O  O    . GLN A 1 198 ? 25.206  -1.369  16.475  1.00 47.35  ? 405 GLN A O    1 
ATOM   1504  C  CB   . GLN A 1 198 ? 26.523  0.202   18.662  1.00 39.98  ? 405 GLN A CB   1 
ATOM   1505  C  CG   . GLN A 1 198 ? 26.072  1.485   17.997  1.00 41.90  ? 405 GLN A CG   1 
ATOM   1506  C  CD   . GLN A 1 198 ? 27.248  2.403   17.731  1.00 45.04  ? 405 GLN A CD   1 
ATOM   1507  O  OE1  . GLN A 1 198 ? 28.385  1.942   17.590  1.00 45.83  ? 405 GLN A OE1  1 
ATOM   1508  N  NE2  . GLN A 1 198 ? 26.989  3.700   17.668  1.00 43.65  ? 405 GLN A NE2  1 
ATOM   1509  N  N    . LEU A 1 199 ? 23.330  -0.800  17.568  1.00 43.16  ? 406 LEU A N    1 
ATOM   1510  C  CA   . LEU A 1 199 ? 22.543  -0.966  16.359  1.00 48.34  ? 406 LEU A CA   1 
ATOM   1511  C  C    . LEU A 1 199 ? 22.638  0.310   15.554  1.00 48.12  ? 406 LEU A C    1 
ATOM   1512  O  O    . LEU A 1 199 ? 22.396  1.396   16.076  1.00 50.71  ? 406 LEU A O    1 
ATOM   1513  C  CB   . LEU A 1 199 ? 21.077  -1.287  16.663  1.00 46.33  ? 406 LEU A CB   1 
ATOM   1514  C  CG   . LEU A 1 199 ? 20.781  -2.276  17.767  1.00 40.42  ? 406 LEU A CG   1 
ATOM   1515  C  CD1  . LEU A 1 199 ? 19.293  -2.524  17.819  1.00 47.89  ? 406 LEU A CD1  1 
ATOM   1516  C  CD2  . LEU A 1 199 ? 21.571  -3.584  17.569  1.00 36.15  ? 406 LEU A CD2  1 
ATOM   1517  N  N    . MET A 1 200 ? 22.946  0.172   14.271  1.00 48.78  ? 407 MET A N    1 
ATOM   1518  C  CA   . MET A 1 200 ? 23.129  1.314   13.388  1.00 48.72  ? 407 MET A CA   1 
ATOM   1519  C  C    . MET A 1 200 ? 21.794  1.938   12.956  1.00 52.10  ? 407 MET A C    1 
ATOM   1520  O  O    . MET A 1 200 ? 21.431  1.993   11.781  1.00 55.76  ? 407 MET A O    1 
ATOM   1521  C  CB   . MET A 1 200 ? 23.954  0.852   12.205  1.00 48.64  ? 407 MET A CB   1 
ATOM   1522  C  CG   . MET A 1 200 ? 25.213  0.207   12.701  1.00 55.76  ? 407 MET A CG   1 
ATOM   1523  S  SD   . MET A 1 200 ? 26.330  1.548   13.008  1.00 53.61  ? 407 MET A SD   1 
ATOM   1524  C  CE   . MET A 1 200 ? 27.108  1.552   11.393  1.00 40.76  ? 407 MET A CE   1 
ATOM   1525  N  N    . ARG A 1 201 ? 21.066  2.464   13.934  1.00 49.05  ? 408 ARG A N    1 
ATOM   1526  C  CA   . ARG A 1 201 ? 19.726  3.029   13.657  1.00 52.68  ? 408 ARG A CA   1 
ATOM   1527  C  C    . ARG A 1 201 ? 19.868  4.448   13.122  1.00 50.61  ? 408 ARG A C    1 
ATOM   1528  O  O    . ARG A 1 201 ? 19.202  5.340   13.645  1.00 51.03  ? 408 ARG A O    1 
ATOM   1529  C  CB   . ARG A 1 201 ? 18.900  2.985   14.940  1.00 46.60  ? 408 ARG A CB   1 
ATOM   1530  C  CG   . ARG A 1 201 ? 18.544  1.581   15.390  1.00 52.09  ? 408 ARG A CG   1 
ATOM   1531  C  CD   . ARG A 1 201 ? 17.211  1.693   16.082  1.00 54.20  ? 408 ARG A CD   1 
ATOM   1532  N  NE   . ARG A 1 201 ? 16.599  0.413   16.386  1.00 57.33  ? 408 ARG A NE   1 
ATOM   1533  C  CZ   . ARG A 1 201 ? 15.590  -0.107  15.709  1.00 57.91  ? 408 ARG A CZ   1 
ATOM   1534  N  NH1  . ARG A 1 201 ? 15.086  0.546   14.679  1.00 56.03  ? 408 ARG A NH1  1 
ATOM   1535  N  NH2  . ARG A 1 201 ? 15.086  -1.273  16.066  1.00 53.50  ? 408 ARG A NH2  1 
ATOM   1536  N  N    . PHE A 1 202 ? 20.711  4.622   12.110  1.00 53.50  ? 409 PHE A N    1 
ATOM   1537  C  CA   . PHE A 1 202 ? 20.889  5.957   11.490  1.00 56.64  ? 409 PHE A CA   1 
ATOM   1538  C  C    . PHE A 1 202 ? 21.316  5.845   10.023  1.00 59.98  ? 409 PHE A C    1 
ATOM   1539  O  O    . PHE A 1 202 ? 21.950  4.846   9.651   1.00 59.59  ? 409 PHE A O    1 
ATOM   1540  C  CB   . PHE A 1 202 ? 21.874  6.831   12.274  1.00 54.72  ? 409 PHE A CB   1 
ATOM   1541  C  CG   . PHE A 1 202 ? 22.979  6.149   13.033  1.00 55.70  ? 409 PHE A CG   1 
ATOM   1542  C  CD1  . PHE A 1 202 ? 23.952  5.412   12.380  1.00 56.56  ? 409 PHE A CD1  1 
ATOM   1543  C  CD2  . PHE A 1 202 ? 23.075  6.300   14.406  1.00 55.47  ? 409 PHE A CD2  1 
ATOM   1544  C  CE1  . PHE A 1 202 ? 24.971  4.808   13.093  1.00 61.03  ? 409 PHE A CE1  1 
ATOM   1545  C  CE2  . PHE A 1 202 ? 24.097  5.696   15.116  1.00 52.76  ? 409 PHE A CE2  1 
ATOM   1546  C  CZ   . PHE A 1 202 ? 25.039  4.946   14.459  1.00 60.77  ? 409 PHE A CZ   1 
ATOM   1547  N  N    . MET A 1 203 ? 20.958  6.846   9.221   1.00 63.69  ? 410 MET A N    1 
ATOM   1548  C  CA   . MET A 1 203 ? 21.376  6.907   7.796   1.00 67.46  ? 410 MET A CA   1 
ATOM   1549  C  C    . MET A 1 203 ? 21.322  8.368   7.341   1.00 76.95  ? 410 MET A C    1 
ATOM   1550  O  O    . MET A 1 203 ? 20.529  9.139   7.908   1.00 78.27  ? 410 MET A O    1 
ATOM   1551  C  CB   . MET A 1 203 ? 20.509  6.039   6.877   1.00 70.57  ? 410 MET A CB   1 
ATOM   1552  C  CG   . MET A 1 203 ? 19.034  6.377   6.833   1.00 73.18  ? 410 MET A CG   1 
ATOM   1553  S  SD   . MET A 1 203 ? 18.163  5.160   5.807   1.00 90.54  ? 410 MET A SD   1 
ATOM   1554  C  CE   . MET A 1 203 ? 16.488  5.336   6.418   1.00 78.42  ? 410 MET A CE   1 
ATOM   1555  N  N    . TYR A 1 204 ? 22.157  8.735   6.375   1.00 74.71  ? 411 TYR A N    1 
ATOM   1556  C  CA   . TYR A 1 204 ? 22.232  10.146  5.928   1.00 74.61  ? 411 TYR A CA   1 
ATOM   1557  C  C    . TYR A 1 204 ? 21.851  10.199  4.446   1.00 77.07  ? 411 TYR A C    1 
ATOM   1558  O  O    . TYR A 1 204 ? 22.361  9.367   3.678   1.00 73.08  ? 411 TYR A O    1 
ATOM   1559  C  CB   . TYR A 1 204 ? 23.623  10.700  6.259   1.00 72.01  ? 411 TYR A CB   1 
ATOM   1560  C  CG   . TYR A 1 204 ? 24.002  12.005  5.607   1.00 77.43  ? 411 TYR A CG   1 
ATOM   1561  C  CD1  . TYR A 1 204 ? 23.735  13.213  6.227   1.00 85.01  ? 411 TYR A CD1  1 
ATOM   1562  C  CD2  . TYR A 1 204 ? 24.660  12.037  4.389   1.00 73.39  ? 411 TYR A CD2  1 
ATOM   1563  C  CE1  . TYR A 1 204 ? 24.079  14.418  5.641   1.00 84.53  ? 411 TYR A CE1  1 
ATOM   1564  C  CE2  . TYR A 1 204 ? 25.010  13.232  3.787   1.00 75.03  ? 411 TYR A CE2  1 
ATOM   1565  C  CZ   . TYR A 1 204 ? 24.716  14.428  4.414   1.00 81.81  ? 411 TYR A CZ   1 
ATOM   1566  O  OH   . TYR A 1 204 ? 25.068  15.611  3.833   1.00 85.22  ? 411 TYR A OH   1 
ATOM   1567  N  N    . THR A 1 208 ? 18.386  15.722  0.922   1.00 80.80  ? 415 THR A N    1 
ATOM   1568  C  CA   . THR A 1 208 ? 17.837  16.242  2.172   1.00 87.98  ? 415 THR A CA   1 
ATOM   1569  C  C    . THR A 1 208 ? 18.996  16.612  3.118   1.00 95.99  ? 415 THR A C    1 
ATOM   1570  O  O    . THR A 1 208 ? 18.870  17.537  3.937   1.00 91.20  ? 415 THR A O    1 
ATOM   1571  C  CB   . THR A 1 208 ? 16.864  15.223  2.860   1.00 84.94  ? 415 THR A CB   1 
ATOM   1572  O  OG1  . THR A 1 208 ? 15.888  14.752  1.919   1.00 79.97  ? 415 THR A OG1  1 
ATOM   1573  C  CG2  . THR A 1 208 ? 16.131  15.868  4.035   1.00 81.74  ? 415 THR A CG2  1 
ATOM   1574  N  N    . ASP A 1 209 ? 20.141  15.938  2.951   1.00 96.79  ? 416 ASP A N    1 
ATOM   1575  C  CA   . ASP A 1 209 ? 21.371  16.267  3.727   1.00 94.91  ? 416 ASP A CA   1 
ATOM   1576  C  C    . ASP A 1 209 ? 21.075  16.405  5.223   1.00 94.60  ? 416 ASP A C    1 
ATOM   1577  O  O    . ASP A 1 209 ? 21.333  17.486  5.787   1.00 93.47  ? 416 ASP A O    1 
ATOM   1578  C  CB   . ASP A 1 209 ? 22.074  17.500  3.150   1.00 89.34  ? 416 ASP A CB   1 
ATOM   1579  N  N    . GLN A 1 210 ? 20.609  15.326  5.845   1.00 91.69  ? 417 GLN A N    1 
ATOM   1580  C  CA   . GLN A 1 210 ? 20.350  15.349  7.281   1.00 88.32  ? 417 GLN A CA   1 
ATOM   1581  C  C    . GLN A 1 210 ? 20.634  13.979  7.891   1.00 83.55  ? 417 GLN A C    1 
ATOM   1582  O  O    . GLN A 1 210 ? 20.669  12.957  7.196   1.00 82.90  ? 417 GLN A O    1 
ATOM   1583  N  N    . ASN A 1 211 ? 20.809  13.992  9.215   1.00 78.49  ? 418 ASN A N    1 
ATOM   1584  C  CA   . ASN A 1 211 ? 20.961  12.722  9.961   1.00 78.36  ? 418 ASN A CA   1 
ATOM   1585  C  C    . ASN A 1 211 ? 19.557  12.228  10.286  1.00 74.18  ? 418 ASN A C    1 
ATOM   1586  O  O    . ASN A 1 211 ? 18.822  12.949  10.976  1.00 84.42  ? 418 ASN A O    1 
ATOM   1587  C  CB   . ASN A 1 211 ? 21.790  12.897  11.232  1.00 77.92  ? 418 ASN A CB   1 
ATOM   1588  N  N    . ILE A 1 212 ? 19.196  11.059  9.789   1.00 67.01  ? 419 ILE A N    1 
ATOM   1589  C  CA   . ILE A 1 212 ? 17.864  10.503  9.979   1.00 64.29  ? 419 ILE A CA   1 
ATOM   1590  C  C    . ILE A 1 212 ? 17.979  9.215   10.779  1.00 65.37  ? 419 ILE A C    1 
ATOM   1591  O  O    . ILE A 1 212 ? 18.759  8.326   10.423  1.00 65.91  ? 419 ILE A O    1 
ATOM   1592  C  CB   . ILE A 1 212 ? 17.162  10.252  8.630   1.00 69.09  ? 419 ILE A CB   1 
ATOM   1593  C  CG1  . ILE A 1 212 ? 16.727  11.586  8.003   1.00 67.30  ? 419 ILE A CG1  1 
ATOM   1594  C  CG2  . ILE A 1 212 ? 15.993  9.300   8.806   1.00 62.81  ? 419 ILE A CG2  1 
ATOM   1595  C  CD1  . ILE A 1 212 ? 16.079  11.450  6.644   1.00 71.31  ? 419 ILE A CD1  1 
ATOM   1596  N  N    . LYS A 1 213 ? 17.205  9.118   11.857  1.00 63.81  ? 420 LYS A N    1 
ATOM   1597  C  CA   . LYS A 1 213 ? 17.128  7.889   12.639  1.00 59.14  ? 420 LYS A CA   1 
ATOM   1598  C  C    . LYS A 1 213 ? 16.298  6.828   11.915  1.00 62.96  ? 420 LYS A C    1 
ATOM   1599  O  O    . LYS A 1 213 ? 15.238  7.122   11.345  1.00 63.88  ? 420 LYS A O    1 
ATOM   1600  C  CB   . LYS A 1 213 ? 16.531  8.175   14.023  1.00 58.15  ? 420 LYS A CB   1 
ATOM   1601  C  CG   . LYS A 1 213 ? 16.244  6.922   14.854  1.00 59.17  ? 420 LYS A CG   1 
ATOM   1602  C  CD   . LYS A 1 213 ? 15.660  7.237   16.220  1.00 53.58  ? 420 LYS A CD   1 
ATOM   1603  C  CE   . LYS A 1 213 ? 15.777  6.011   17.102  1.00 57.90  ? 420 LYS A CE   1 
ATOM   1604  N  NZ   . LYS A 1 213 ? 14.885  6.086   18.300  1.00 61.40  ? 420 LYS A NZ   1 
ATOM   1605  N  N    . ILE A 1 214 ? 16.798  5.590   11.933  1.00 53.78  ? 421 ILE A N    1 
ATOM   1606  C  CA   . ILE A 1 214 ? 16.049  4.443   11.356  1.00 53.38  ? 421 ILE A CA   1 
ATOM   1607  C  C    . ILE A 1 214 ? 15.256  3.806   12.488  1.00 55.86  ? 421 ILE A C    1 
ATOM   1608  O  O    . ILE A 1 214 ? 15.870  3.259   13.400  1.00 52.39  ? 421 ILE A O    1 
ATOM   1609  C  CB   . ILE A 1 214 ? 16.998  3.410   10.726  1.00 56.31  ? 421 ILE A CB   1 
ATOM   1610  C  CG1  . ILE A 1 214 ? 17.950  4.023   9.702   1.00 59.24  ? 421 ILE A CG1  1 
ATOM   1611  C  CG2  . ILE A 1 214 ? 16.221  2.251   10.128  1.00 57.62  ? 421 ILE A CG2  1 
ATOM   1612  C  CD1  . ILE A 1 214 ? 18.894  3.014   9.101   1.00 60.12  ? 421 ILE A CD1  1 
ATOM   1613  N  N    . ASN A 1 215 ? 13.936  3.893   12.429  1.00 58.14  ? 422 ASN A N    1 
ATOM   1614  C  CA   . ASN A 1 215 ? 13.088  3.267   13.437  1.00 58.07  ? 422 ASN A CA   1 
ATOM   1615  C  C    . ASN A 1 215 ? 12.445  1.971   12.950  1.00 56.41  ? 422 ASN A C    1 
ATOM   1616  O  O    . ASN A 1 215 ? 11.471  1.507   13.557  1.00 55.24  ? 422 ASN A O    1 
ATOM   1617  C  CB   . ASN A 1 215 ? 12.016  4.245   13.912  1.00 56.85  ? 422 ASN A CB   1 
ATOM   1618  C  CG   . ASN A 1 215 ? 12.592  5.584   14.314  1.00 58.46  ? 422 ASN A CG   1 
ATOM   1619  O  OD1  . ASN A 1 215 ? 12.990  5.780   15.459  1.00 60.35  ? 422 ASN A OD1  1 
ATOM   1620  N  ND2  . ASN A 1 215 ? 12.628  6.519   13.372  1.00 61.20  ? 422 ASN A ND2  1 
ATOM   1621  N  N    . ASP A 1 216 ? 13.027  1.361   11.929  1.00 52.66  ? 423 ASP A N    1 
ATOM   1622  C  CA   . ASP A 1 216 ? 12.453  0.125   11.350  1.00 51.57  ? 423 ASP A CA   1 
ATOM   1623  C  C    . ASP A 1 216 ? 12.483  -1.020  12.369  1.00 56.21  ? 423 ASP A C    1 
ATOM   1624  O  O    . ASP A 1 216 ? 13.291  -0.985  13.298  1.00 56.90  ? 423 ASP A O    1 
ATOM   1625  C  CB   . ASP A 1 216 ? 13.148  -0.210  10.030  1.00 55.48  ? 423 ASP A CB   1 
ATOM   1626  C  CG   . ASP A 1 216 ? 13.078  0.887   8.982   1.00 60.22  ? 423 ASP A CG   1 
ATOM   1627  O  OD1  . ASP A 1 216 ? 12.368  1.883   9.209   1.00 60.36  ? 423 ASP A OD1  1 
ATOM   1628  O  OD2  . ASP A 1 216 ? 13.743  0.733   7.942   1.00 61.24  ? 423 ASP A OD2  1 
ATOM   1629  N  N    . ARG A 1 217 ? 11.627  -2.018  12.167  1.00 59.43  ? 424 ARG A N    1 
ATOM   1630  C  CA   . ARG A 1 217 ? 11.556  -3.160  13.110  1.00 57.10  ? 424 ARG A CA   1 
ATOM   1631  C  C    . ARG A 1 217 ? 12.844  -3.975  13.029  1.00 53.95  ? 424 ARG A C    1 
ATOM   1632  O  O    . ARG A 1 217 ? 13.233  -4.364  11.923  1.00 56.79  ? 424 ARG A O    1 
ATOM   1633  C  CB   . ARG A 1 217 ? 10.314  -4.022  12.863  1.00 48.72  ? 424 ARG A CB   1 
ATOM   1634  C  CG   . ARG A 1 217 ? 10.347  -5.365  13.578  1.00 50.08  ? 424 ARG A CG   1 
ATOM   1635  C  CD   . ARG A 1 217 ? 9.080   -6.188  13.503  1.00 48.99  ? 424 ARG A CD   1 
ATOM   1636  N  NE   . ARG A 1 217 ? 8.620   -6.510  14.846  1.00 59.79  ? 424 ARG A NE   1 
ATOM   1637  C  CZ   . ARG A 1 217 ? 8.025   -7.640  15.204  1.00 56.44  ? 424 ARG A CZ   1 
ATOM   1638  N  NH1  . ARG A 1 217 ? 7.800   -8.587  14.313  1.00 54.09  ? 424 ARG A NH1  1 
ATOM   1639  N  NH2  . ARG A 1 217 ? 7.647   -7.818  16.455  1.00 61.02  ? 424 ARG A NH2  1 
ATOM   1640  N  N    . PHE A 1 218 ? 13.484  -4.191  14.170  1.00 51.18  ? 425 PHE A N    1 
ATOM   1641  C  CA   . PHE A 1 218 ? 14.695  -5.034  14.236  1.00 49.93  ? 425 PHE A CA   1 
ATOM   1642  C  C    . PHE A 1 218 ? 14.556  -5.921  15.462  1.00 49.60  ? 425 PHE A C    1 
ATOM   1643  O  O    . PHE A 1 218 ? 14.634  -5.424  16.589  1.00 53.13  ? 425 PHE A O    1 
ATOM   1644  C  CB   . PHE A 1 218 ? 15.953  -4.179  14.310  1.00 52.68  ? 425 PHE A CB   1 
ATOM   1645  C  CG   . PHE A 1 218 ? 17.234  -4.949  14.165  1.00 53.57  ? 425 PHE A CG   1 
ATOM   1646  C  CD1  . PHE A 1 218 ? 17.672  -5.352  12.917  1.00 50.62  ? 425 PHE A CD1  1 
ATOM   1647  C  CD2  . PHE A 1 218 ? 17.996  -5.267  15.276  1.00 50.70  ? 425 PHE A CD2  1 
ATOM   1648  C  CE1  . PHE A 1 218 ? 18.859  -6.048  12.781  1.00 54.77  ? 425 PHE A CE1  1 
ATOM   1649  C  CE2  . PHE A 1 218 ? 19.179  -5.970  15.139  1.00 55.13  ? 425 PHE A CE2  1 
ATOM   1650  C  CZ   . PHE A 1 218 ? 19.610  -6.347  13.891  1.00 53.09  ? 425 PHE A CZ   1 
ATOM   1651  N  N    . GLU A 1 219 ? 14.342  -7.206  15.229  1.00 55.40  ? 426 GLU A N    1 
ATOM   1652  C  CA   . GLU A 1 219 ? 14.123  -8.126  16.361  1.00 58.47  ? 426 GLU A CA   1 
ATOM   1653  C  C    . GLU A 1 219 ? 15.439  -8.615  16.942  1.00 57.80  ? 426 GLU A C    1 
ATOM   1654  O  O    . GLU A 1 219 ? 16.416  -8.703  16.208  1.00 58.77  ? 426 GLU A O    1 
ATOM   1655  C  CB   . GLU A 1 219 ? 13.256  -9.297  15.905  1.00 50.70  ? 426 GLU A CB   1 
ATOM   1656  C  CG   . GLU A 1 219 ? 12.109  -8.889  15.001  1.00 56.99  ? 426 GLU A CG   1 
ATOM   1657  C  CD   . GLU A 1 219 ? 11.331  -10.036 14.381  1.00 59.92  ? 426 GLU A CD   1 
ATOM   1658  O  OE1  . GLU A 1 219 ? 11.777  -11.190 14.500  1.00 63.27  ? 426 GLU A OE1  1 
ATOM   1659  O  OE2  . GLU A 1 219 ? 10.284  -9.769  13.775  1.00 60.13  ? 426 GLU A OE2  1 
ATOM   1660  N  N    . PHE A 1 220 ? 15.448  -8.790  18.259  1.00 56.39  ? 427 PHE A N    1 
ATOM   1661  C  CA   . PHE A 1 220 ? 16.636  -9.299  18.975  1.00 50.07  ? 427 PHE A CA   1 
ATOM   1662  C  C    . PHE A 1 220 ? 16.129  -10.350 19.950  1.00 51.15  ? 427 PHE A C    1 
ATOM   1663  O  O    . PHE A 1 220 ? 15.013  -10.226 20.452  1.00 51.60  ? 427 PHE A O    1 
ATOM   1664  C  CB   . PHE A 1 220 ? 17.404  -8.170  19.667  1.00 47.12  ? 427 PHE A CB   1 
ATOM   1665  C  CG   . PHE A 1 220 ? 16.620  -7.219  20.531  1.00 52.28  ? 427 PHE A CG   1 
ATOM   1666  C  CD1  . PHE A 1 220 ? 16.486  -7.446  21.889  1.00 51.04  ? 427 PHE A CD1  1 
ATOM   1667  C  CD2  . PHE A 1 220 ? 16.075  -6.063  19.998  1.00 52.19  ? 427 PHE A CD2  1 
ATOM   1668  C  CE1  . PHE A 1 220 ? 15.784  -6.559  22.687  1.00 46.75  ? 427 PHE A CE1  1 
ATOM   1669  C  CE2  . PHE A 1 220 ? 15.368  -5.182  20.797  1.00 49.21  ? 427 PHE A CE2  1 
ATOM   1670  C  CZ   . PHE A 1 220 ? 15.227  -5.430  22.139  1.00 45.62  ? 427 PHE A CZ   1 
ATOM   1671  N  N    . PRO A 1 221 ? 16.898  -11.411 20.220  1.00 52.90  ? 428 PRO A N    1 
ATOM   1672  C  CA   . PRO A 1 221 ? 16.419  -12.467 21.074  1.00 54.35  ? 428 PRO A CA   1 
ATOM   1673  C  C    . PRO A 1 221 ? 16.841  -12.423 22.538  1.00 57.74  ? 428 PRO A C    1 
ATOM   1674  O  O    . PRO A 1 221 ? 17.669  -11.620 22.897  1.00 62.16  ? 428 PRO A O    1 
ATOM   1675  C  CB   . PRO A 1 221 ? 17.147  -13.652 20.443  1.00 55.62  ? 428 PRO A CB   1 
ATOM   1676  C  CG   . PRO A 1 221 ? 18.498  -13.107 20.086  1.00 60.26  ? 428 PRO A CG   1 
ATOM   1677  C  CD   . PRO A 1 221 ? 18.205  -11.694 19.645  1.00 54.63  ? 428 PRO A CD   1 
ATOM   1678  N  N    . GLU A 1 222 ? 16.192  -13.241 23.359  1.00 59.33  ? 429 GLU A N    1 
ATOM   1679  C  CA   . GLU A 1 222 ? 16.660  -13.380 24.738  1.00 58.47  ? 429 GLU A CA   1 
ATOM   1680  C  C    . GLU A 1 222 ? 17.945  -14.207 24.822  1.00 57.48  ? 429 GLU A C    1 
ATOM   1681  O  O    . GLU A 1 222 ? 18.851  -13.873 25.594  1.00 59.29  ? 429 GLU A O    1 
ATOM   1682  C  CB   . GLU A 1 222 ? 15.567  -14.009 25.604  1.00 53.20  ? 429 GLU A CB   1 
ATOM   1683  C  CG   . GLU A 1 222 ? 15.909  -14.053 27.100  1.00 72.37  ? 429 GLU A CG   1 
ATOM   1684  C  CD   . GLU A 1 222 ? 14.669  -14.119 28.004  1.00 73.76  ? 429 GLU A CD   1 
ATOM   1685  O  OE1  . GLU A 1 222 ? 14.626  -13.407 29.052  1.00 71.89  ? 429 GLU A OE1  1 
ATOM   1686  O  OE2  . GLU A 1 222 ? 13.745  -14.881 27.653  1.00 59.16  ? 429 GLU A OE2  1 
ATOM   1687  N  N    . GLN A 1 223 ? 18.029  -15.252 23.999  1.00 57.35  ? 430 GLN A N    1 
ATOM   1688  C  CA   . GLN A 1 223 ? 19.248  -16.092 23.929  1.00 56.50  ? 430 GLN A CA   1 
ATOM   1689  C  C    . GLN A 1 223 ? 19.840  -15.961 22.524  1.00 59.03  ? 430 GLN A C    1 
ATOM   1690  O  O    . GLN A 1 223 ? 19.085  -16.134 21.566  1.00 64.13  ? 430 GLN A O    1 
ATOM   1691  C  CB   . GLN A 1 223 ? 18.906  -17.546 24.241  1.00 64.50  ? 430 GLN A CB   1 
ATOM   1692  C  CG   . GLN A 1 223 ? 18.552  -17.816 25.692  1.00 63.02  ? 430 GLN A CG   1 
ATOM   1693  C  CD   . GLN A 1 223 ? 18.852  -19.247 26.059  1.00 74.39  ? 430 GLN A CD   1 
ATOM   1694  O  OE1  . GLN A 1 223 ? 20.005  -19.667 26.117  1.00 71.14  ? 430 GLN A OE1  1 
ATOM   1695  N  NE2  . GLN A 1 223 ? 17.805  -20.018 26.299  1.00 75.54  ? 430 GLN A NE2  1 
ATOM   1696  N  N    . LEU A 1 224 ? 21.143  -15.691 22.410  1.00 59.28  ? 431 LEU A N    1 
ATOM   1697  C  CA   . LEU A 1 224 ? 21.776  -15.449 21.086  1.00 53.88  ? 431 LEU A CA   1 
ATOM   1698  C  C    . LEU A 1 224 ? 22.915  -16.431 20.846  1.00 54.63  ? 431 LEU A C    1 
ATOM   1699  O  O    . LEU A 1 224 ? 23.960  -16.301 21.489  1.00 56.69  ? 431 LEU A O    1 
ATOM   1700  C  CB   . LEU A 1 224 ? 22.276  -14.007 21.050  1.00 53.69  ? 431 LEU A CB   1 
ATOM   1701  C  CG   . LEU A 1 224 ? 23.019  -13.548 19.803  1.00 53.08  ? 431 LEU A CG   1 
ATOM   1702  C  CD1  . LEU A 1 224 ? 22.184  -13.739 18.554  1.00 47.76  ? 431 LEU A CD1  1 
ATOM   1703  C  CD2  . LEU A 1 224 ? 23.432  -12.097 19.950  1.00 55.11  ? 431 LEU A CD2  1 
ATOM   1704  N  N    . PRO A 1 225 ? 22.733  -17.429 19.964  1.00 55.02  ? 432 PRO A N    1 
ATOM   1705  C  CA   . PRO A 1 225 ? 23.828  -18.317 19.598  1.00 59.01  ? 432 PRO A CA   1 
ATOM   1706  C  C    . PRO A 1 225 ? 24.777  -17.647 18.595  1.00 55.33  ? 432 PRO A C    1 
ATOM   1707  O  O    . PRO A 1 225 ? 24.346  -17.282 17.528  1.00 52.78  ? 432 PRO A O    1 
ATOM   1708  C  CB   . PRO A 1 225 ? 23.085  -19.500 18.973  1.00 59.90  ? 432 PRO A CB   1 
ATOM   1709  C  CG   . PRO A 1 225 ? 21.790  -18.936 18.447  1.00 57.81  ? 432 PRO A CG   1 
ATOM   1710  C  CD   . PRO A 1 225 ? 21.455  -17.789 19.368  1.00 53.24  ? 432 PRO A CD   1 
ATOM   1711  N  N    . LEU A 1 226 ? 26.049  -17.492 18.966  1.00 55.88  ? 433 LEU A N    1 
ATOM   1712  C  CA   . LEU A 1 226 ? 26.979  -16.799 18.085  1.00 51.94  ? 433 LEU A CA   1 
ATOM   1713  C  C    . LEU A 1 226 ? 28.088  -17.699 17.560  1.00 50.45  ? 433 LEU A C    1 
ATOM   1714  O  O    . LEU A 1 226 ? 29.037  -17.194 16.958  1.00 54.72  ? 433 LEU A O    1 
ATOM   1715  C  CB   . LEU A 1 226 ? 27.569  -15.582 18.802  1.00 46.50  ? 433 LEU A CB   1 
ATOM   1716  C  CG   . LEU A 1 226 ? 26.566  -14.445 19.018  1.00 45.03  ? 433 LEU A CG   1 
ATOM   1717  C  CD1  . LEU A 1 226 ? 27.181  -13.293 19.825  1.00 45.80  ? 433 LEU A CD1  1 
ATOM   1718  C  CD2  . LEU A 1 226 ? 26.029  -13.944 17.676  1.00 45.32  ? 433 LEU A CD2  1 
ATOM   1719  N  N    . ASP A 1 227 ? 27.988  -19.021 17.753  1.00 57.14  ? 434 ASP A N    1 
ATOM   1720  C  CA   . ASP A 1 227 ? 29.050  -19.920 17.300  1.00 54.84  ? 434 ASP A CA   1 
ATOM   1721  C  C    . ASP A 1 227 ? 29.237  -19.833 15.800  1.00 52.61  ? 434 ASP A C    1 
ATOM   1722  O  O    . ASP A 1 227 ? 30.357  -19.990 15.302  1.00 51.14  ? 434 ASP A O    1 
ATOM   1723  C  CB   . ASP A 1 227 ? 28.749  -21.363 17.709  1.00 52.26  ? 434 ASP A CB   1 
ATOM   1724  C  CG   . ASP A 1 227 ? 29.547  -21.811 18.938  1.00 61.16  ? 434 ASP A CG   1 
ATOM   1725  O  OD1  . ASP A 1 227 ? 30.416  -21.042 19.432  1.00 58.49  ? 434 ASP A OD1  1 
ATOM   1726  O  OD2  . ASP A 1 227 ? 29.295  -22.939 19.417  1.00 64.50  ? 434 ASP A OD2  1 
ATOM   1727  N  N    . GLU A 1 228 ? 28.165  -19.537 15.072  1.00 54.37  ? 435 GLU A N    1 
ATOM   1728  C  CA   . GLU A 1 228 ? 28.239  -19.504 13.619  1.00 53.90  ? 435 GLU A CA   1 
ATOM   1729  C  C    . GLU A 1 228 ? 29.184  -18.426 13.113  1.00 56.54  ? 435 GLU A C    1 
ATOM   1730  O  O    . GLU A 1 228 ? 29.714  -18.547 12.003  1.00 65.01  ? 435 GLU A O    1 
ATOM   1731  C  CB   . GLU A 1 228 ? 26.834  -19.310 13.050  1.00 55.96  ? 435 GLU A CB   1 
ATOM   1732  C  CG   . GLU A 1 228 ? 26.778  -18.776 11.638  1.00 63.10  ? 435 GLU A CG   1 
ATOM   1733  C  CD   . GLU A 1 228 ? 26.936  -19.865 10.585  1.00 66.92  ? 435 GLU A CD   1 
ATOM   1734  O  OE1  . GLU A 1 228 ? 26.407  -19.691 9.467   1.00 76.96  ? 435 GLU A OE1  1 
ATOM   1735  O  OE2  . GLU A 1 228 ? 27.590  -20.886 10.874  1.00 67.80  ? 435 GLU A OE2  1 
ATOM   1736  N  N    . PHE A 1 229 ? 29.445  -17.390 13.903  1.00 55.34  ? 436 PHE A N    1 
ATOM   1737  C  CA   . PHE A 1 229 ? 30.262  -16.279 13.437  1.00 54.68  ? 436 PHE A CA   1 
ATOM   1738  C  C    . PHE A 1 229 ? 31.650  -16.267 14.075  1.00 53.59  ? 436 PHE A C    1 
ATOM   1739  O  O    . PHE A 1 229 ? 32.296  -15.213 14.128  1.00 56.11  ? 436 PHE A O    1 
ATOM   1740  C  CB   . PHE A 1 229 ? 29.511  -14.971 13.674  1.00 46.61  ? 436 PHE A CB   1 
ATOM   1741  C  CG   . PHE A 1 229 ? 28.035  -15.080 13.365  1.00 51.11  ? 436 PHE A CG   1 
ATOM   1742  C  CD1  . PHE A 1 229 ? 27.591  -15.204 12.060  1.00 50.74  ? 436 PHE A CD1  1 
ATOM   1743  C  CD2  . PHE A 1 229 ? 27.089  -15.098 14.378  1.00 55.33  ? 436 PHE A CD2  1 
ATOM   1744  C  CE1  . PHE A 1 229 ? 26.239  -15.307 11.773  1.00 50.15  ? 436 PHE A CE1  1 
ATOM   1745  C  CE2  . PHE A 1 229 ? 25.731  -15.211 14.089  1.00 52.17  ? 436 PHE A CE2  1 
ATOM   1746  C  CZ   . PHE A 1 229 ? 25.313  -15.318 12.789  1.00 48.88  ? 436 PHE A CZ   1 
ATOM   1747  N  N    . LEU A 1 230 ? 32.126  -17.417 14.551  1.00 52.24  ? 437 LEU A N    1 
ATOM   1748  C  CA   . LEU A 1 230 ? 33.487  -17.573 15.051  1.00 53.18  ? 437 LEU A CA   1 
ATOM   1749  C  C    . LEU A 1 230 ? 34.333  -18.305 14.020  1.00 49.97  ? 437 LEU A C    1 
ATOM   1750  O  O    . LEU A 1 230 ? 33.827  -19.075 13.208  1.00 53.26  ? 437 LEU A O    1 
ATOM   1751  C  CB   . LEU A 1 230 ? 33.523  -18.357 16.367  1.00 45.55  ? 437 LEU A CB   1 
ATOM   1752  C  CG   . LEU A 1 230 ? 33.179  -17.653 17.678  1.00 51.78  ? 437 LEU A CG   1 
ATOM   1753  C  CD1  . LEU A 1 230 ? 32.892  -18.740 18.745  1.00 42.35  ? 437 LEU A CD1  1 
ATOM   1754  C  CD2  . LEU A 1 230 ? 34.267  -16.659 18.132  1.00 46.04  ? 437 LEU A CD2  1 
ATOM   1755  N  N    . GLN A 1 231 ? 35.635  -18.063 14.023  1.00 51.22  ? 438 GLN A N    1 
ATOM   1756  C  CA   . GLN A 1 231 ? 36.530  -18.805 13.106  1.00 55.23  ? 438 GLN A CA   1 
ATOM   1757  C  C    . GLN A 1 231 ? 36.613  -20.241 13.603  1.00 58.80  ? 438 GLN A C    1 
ATOM   1758  O  O    . GLN A 1 231 ? 36.391  -21.153 12.799  1.00 60.03  ? 438 GLN A O    1 
ATOM   1759  C  CB   . GLN A 1 231 ? 37.904  -18.146 13.077  1.00 55.96  ? 438 GLN A CB   1 
ATOM   1760  C  CG   . GLN A 1 231 ? 38.931  -18.866 12.220  1.00 56.69  ? 438 GLN A CG   1 
ATOM   1761  C  CD   . GLN A 1 231 ? 38.678  -18.745 10.738  1.00 59.61  ? 438 GLN A CD   1 
ATOM   1762  O  OE1  . GLN A 1 231 ? 37.996  -17.837 10.271  1.00 64.45  ? 438 GLN A OE1  1 
ATOM   1763  N  NE2  . GLN A 1 231 ? 39.244  -19.666 9.979   1.00 58.66  ? 438 GLN A NE2  1 
ATOM   1764  N  N    . LYS A 1 232 ? 36.909  -20.414 14.888  1.00 30.00  ? 439 LYS A N    1 
ATOM   1765  C  CA   . LYS A 1 232 ? 36.951  -21.763 15.490  1.00 30.00  ? 439 LYS A CA   1 
ATOM   1766  C  C    . LYS A 1 232 ? 36.016  -21.817 16.700  1.00 30.00  ? 439 LYS A C    1 
ATOM   1767  O  O    . LYS A 1 232 ? 36.170  -20.983 17.609  1.00 30.00  ? 439 LYS A O    1 
ATOM   1768  C  CB   . LYS A 1 232 ? 38.377  -22.133 15.900  1.00 30.00  ? 439 LYS A CB   1 
ATOM   1769  N  N    . THR A 1 233 ? 35.098  -22.781 16.699  1.00 64.41  ? 440 THR A N    1 
ATOM   1770  C  CA   . THR A 1 233 ? 34.160  -22.964 17.827  1.00 58.48  ? 440 THR A CA   1 
ATOM   1771  C  C    . THR A 1 233 ? 34.842  -23.789 18.911  1.00 67.23  ? 440 THR A C    1 
ATOM   1772  O  O    . THR A 1 233 ? 35.639  -24.666 18.553  1.00 73.42  ? 440 THR A O    1 
ATOM   1773  C  CB   . THR A 1 233 ? 32.882  -23.652 17.343  1.00 57.77  ? 440 THR A CB   1 
ATOM   1774  O  OG1  . THR A 1 233 ? 33.194  -24.976 16.911  1.00 60.03  ? 440 THR A OG1  1 
ATOM   1775  C  CG2  . THR A 1 233 ? 32.208  -22.902 16.216  1.00 55.88  ? 440 THR A CG2  1 
ATOM   1776  N  N    . ASP A 1 234 ? 34.550  -23.505 20.180  1.00 77.49  ? 441 ASP A N    1 
ATOM   1777  C  CA   . ASP A 1 234 ? 35.079  -24.307 21.314  1.00 81.28  ? 441 ASP A CA   1 
ATOM   1778  C  C    . ASP A 1 234 ? 33.943  -25.192 21.820  1.00 84.14  ? 441 ASP A C    1 
ATOM   1779  O  O    . ASP A 1 234 ? 33.001  -24.650 22.421  1.00 84.65  ? 441 ASP A O    1 
ATOM   1780  C  CB   . ASP A 1 234 ? 35.603  -23.413 22.436  1.00 75.33  ? 441 ASP A CB   1 
ATOM   1781  C  CG   . ASP A 1 234 ? 36.272  -24.151 23.578  1.00 82.45  ? 441 ASP A CG   1 
ATOM   1782  O  OD1  . ASP A 1 234 ? 36.653  -25.321 23.387  1.00 80.78  ? 441 ASP A OD1  1 
ATOM   1783  O  OD2  . ASP A 1 234 ? 36.414  -23.539 24.650  1.00 82.15  ? 441 ASP A OD2  1 
ATOM   1784  N  N    . PRO A 1 235 ? 33.968  -26.514 21.561  1.00 86.64  ? 442 PRO A N    1 
ATOM   1785  C  CA   . PRO A 1 235 ? 32.921  -27.417 22.047  1.00 87.59  ? 442 PRO A CA   1 
ATOM   1786  C  C    . PRO A 1 235 ? 32.823  -27.379 23.576  1.00 84.49  ? 442 PRO A C    1 
ATOM   1787  O  O    . PRO A 1 235 ? 31.845  -27.855 24.099  1.00 84.07  ? 442 PRO A O    1 
ATOM   1788  C  CB   . PRO A 1 235 ? 33.396  -28.785 21.562  1.00 88.61  ? 442 PRO A CB   1 
ATOM   1789  C  CG   . PRO A 1 235 ? 34.261  -28.471 20.368  1.00 85.72  ? 442 PRO A CG   1 
ATOM   1790  C  CD   . PRO A 1 235 ? 34.985  -27.208 20.776  1.00 85.82  ? 442 PRO A CD   1 
ATOM   1791  N  N    . LYS A 1 236 ? 33.826  -26.809 24.241  1.00 82.48  ? 443 LYS A N    1 
ATOM   1792  C  CA   . LYS A 1 236 ? 33.789  -26.657 25.692  1.00 82.25  ? 443 LYS A CA   1 
ATOM   1793  C  C    . LYS A 1 236 ? 32.838  -25.538 26.101  1.00 82.84  ? 443 LYS A C    1 
ATOM   1794  O  O    . LYS A 1 236 ? 31.837  -25.776 26.789  1.00 80.82  ? 443 LYS A O    1 
ATOM   1795  C  CB   . LYS A 1 236 ? 35.199  -26.381 26.225  1.00 78.92  ? 443 LYS A CB   1 
ATOM   1796  N  N    . ASP A 1 237 ? 33.153  -24.294 25.685  1.00 77.04  ? 444 ASP A N    1 
ATOM   1797  C  CA   . ASP A 1 237 ? 32.419  -23.066 25.968  1.00 68.82  ? 444 ASP A CA   1 
ATOM   1798  C  C    . ASP A 1 237 ? 31.701  -22.576 24.714  1.00 71.04  ? 444 ASP A C    1 
ATOM   1799  O  O    . ASP A 1 237 ? 32.212  -21.669 24.047  1.00 70.19  ? 444 ASP A O    1 
ATOM   1800  C  CB   . ASP A 1 237 ? 33.393  -21.992 26.472  1.00 66.21  ? 444 ASP A CB   1 
ATOM   1801  C  CG   . ASP A 1 237 ? 32.706  -20.661 26.841  1.00 65.35  ? 444 ASP A CG   1 
ATOM   1802  O  OD1  . ASP A 1 237 ? 31.478  -20.494 26.624  1.00 67.02  ? 444 ASP A OD1  1 
ATOM   1803  O  OD2  . ASP A 1 237 ? 33.411  -19.765 27.366  1.00 64.15  ? 444 ASP A OD2  1 
ATOM   1804  N  N    . PRO A 1 238 ? 30.537  -23.126 24.350  1.00 72.89  ? 445 PRO A N    1 
ATOM   1805  C  CA   . PRO A 1 238 ? 29.807  -22.579 23.192  1.00 66.72  ? 445 PRO A CA   1 
ATOM   1806  C  C    . PRO A 1 238 ? 29.445  -21.114 23.409  1.00 65.04  ? 445 PRO A C    1 
ATOM   1807  O  O    . PRO A 1 238 ? 29.179  -20.672 24.530  1.00 63.70  ? 445 PRO A O    1 
ATOM   1808  C  CB   . PRO A 1 238 ? 28.556  -23.465 23.092  1.00 67.73  ? 445 PRO A CB   1 
ATOM   1809  C  CG   . PRO A 1 238 ? 28.481  -24.203 24.412  1.00 73.09  ? 445 PRO A CG   1 
ATOM   1810  C  CD   . PRO A 1 238 ? 29.894  -24.337 24.886  1.00 72.95  ? 445 PRO A CD   1 
ATOM   1811  N  N    . ALA A 1 239 ? 29.473  -20.351 22.312  1.00 61.50  ? 446 ALA A N    1 
ATOM   1812  C  CA   . ALA A 1 239 ? 29.305  -18.901 22.362  1.00 56.95  ? 446 ALA A CA   1 
ATOM   1813  C  C    . ALA A 1 239 ? 27.823  -18.541 22.406  1.00 57.29  ? 446 ALA A C    1 
ATOM   1814  O  O    . ALA A 1 239 ? 27.266  -17.924 21.498  1.00 57.68  ? 446 ALA A O    1 
ATOM   1815  C  CB   . ALA A 1 239 ? 29.995  -18.236 21.179  1.00 50.25  ? 446 ALA A CB   1 
ATOM   1816  N  N    . ASN A 1 240 ? 27.188  -18.947 23.496  1.00 51.89  ? 447 ASN A N    1 
ATOM   1817  C  CA   . ASN A 1 240 ? 25.782  -18.670 23.725  1.00 51.21  ? 447 ASN A CA   1 
ATOM   1818  C  C    . ASN A 1 240 ? 25.645  -17.530 24.723  1.00 50.10  ? 447 ASN A C    1 
ATOM   1819  O  O    . ASN A 1 240 ? 26.274  -17.549 25.782  1.00 58.12  ? 447 ASN A O    1 
ATOM   1820  C  CB   . ASN A 1 240 ? 25.075  -19.930 24.216  1.00 59.40  ? 447 ASN A CB   1 
ATOM   1821  C  CG   . ASN A 1 240 ? 24.999  -20.982 23.138  1.00 65.91  ? 447 ASN A CG   1 
ATOM   1822  O  OD1  . ASN A 1 240 ? 25.552  -20.793 22.043  1.00 70.80  ? 447 ASN A OD1  1 
ATOM   1823  N  ND2  . ASN A 1 240 ? 24.314  -22.088 23.416  1.00 65.53  ? 447 ASN A ND2  1 
ATOM   1824  N  N    . TYR A 1 241 ? 24.841  -16.548 24.327  1.00 47.60  ? 448 TYR A N    1 
ATOM   1825  C  CA   . TYR A 1 241 ? 24.757  -15.298 25.104  1.00 54.06  ? 448 TYR A CA   1 
ATOM   1826  C  C    . TYR A 1 241 ? 23.346  -15.023 25.615  1.00 57.56  ? 448 TYR A C    1 
ATOM   1827  O  O    . TYR A 1 241 ? 22.383  -15.323 24.917  1.00 59.11  ? 448 TYR A O    1 
ATOM   1828  C  CB   . TYR A 1 241 ? 25.260  -14.155 24.218  1.00 51.25  ? 448 TYR A CB   1 
ATOM   1829  C  CG   . TYR A 1 241 ? 26.758  -14.042 24.163  1.00 47.85  ? 448 TYR A CG   1 
ATOM   1830  C  CD1  . TYR A 1 241 ? 27.516  -14.980 23.489  1.00 51.17  ? 448 TYR A CD1  1 
ATOM   1831  C  CD2  . TYR A 1 241 ? 27.414  -13.007 24.798  1.00 46.33  ? 448 TYR A CD2  1 
ATOM   1832  C  CE1  . TYR A 1 241 ? 28.894  -14.906 23.454  1.00 49.12  ? 448 TYR A CE1  1 
ATOM   1833  C  CE2  . TYR A 1 241 ? 28.792  -12.915 24.776  1.00 40.16  ? 448 TYR A CE2  1 
ATOM   1834  C  CZ   . TYR A 1 241 ? 29.528  -13.866 24.098  1.00 44.80  ? 448 TYR A CZ   1 
ATOM   1835  O  OH   . TYR A 1 241 ? 30.881  -13.801 24.077  1.00 46.91  ? 448 TYR A OH   1 
ATOM   1836  N  N    . ILE A 1 242 ? 23.251  -14.436 26.799  1.00 52.80  ? 449 ILE A N    1 
ATOM   1837  C  CA   . ILE A 1 242 ? 21.985  -14.122 27.461  1.00 57.41  ? 449 ILE A CA   1 
ATOM   1838  C  C    . ILE A 1 242 ? 21.780  -12.611 27.474  1.00 54.71  ? 449 ILE A C    1 
ATOM   1839  O  O    . ILE A 1 242 ? 22.656  -11.859 27.914  1.00 51.58  ? 449 ILE A O    1 
ATOM   1840  C  CB   . ILE A 1 242 ? 21.943  -14.665 28.903  1.00 60.87  ? 449 ILE A CB   1 
ATOM   1841  C  CG1  . ILE A 1 242 ? 22.194  -16.171 28.936  1.00 57.70  ? 449 ILE A CG1  1 
ATOM   1842  C  CG2  . ILE A 1 242 ? 20.626  -14.291 29.558  1.00 58.52  ? 449 ILE A CG2  1 
ATOM   1843  C  CD1  . ILE A 1 242 ? 21.394  -16.954 27.904  1.00 60.93  ? 449 ILE A CD1  1 
ATOM   1844  N  N    . LEU A 1 243 ? 20.608  -12.170 27.031  1.00 55.96  ? 450 LEU A N    1 
ATOM   1845  C  CA   . LEU A 1 243 ? 20.310  -10.751 27.001  1.00 46.85  ? 450 LEU A CA   1 
ATOM   1846  C  C    . LEU A 1 243 ? 20.246  -10.176 28.417  1.00 52.86  ? 450 LEU A C    1 
ATOM   1847  O  O    . LEU A 1 243 ? 19.540  -10.692 29.286  1.00 54.47  ? 450 LEU A O    1 
ATOM   1848  C  CB   . LEU A 1 243 ? 18.999  -10.520 26.274  1.00 51.92  ? 450 LEU A CB   1 
ATOM   1849  C  CG   . LEU A 1 243 ? 18.624  -9.044  26.261  1.00 47.29  ? 450 LEU A CG   1 
ATOM   1850  C  CD1  . LEU A 1 243 ? 19.483  -8.413  25.207  1.00 47.65  ? 450 LEU A CD1  1 
ATOM   1851  C  CD2  . LEU A 1 243 ? 17.177  -8.910  25.914  1.00 45.17  ? 450 LEU A CD2  1 
ATOM   1852  N  N    . HIS A 1 244 ? 20.972  -9.089  28.646  1.00 54.78  ? 451 HIS A N    1 
ATOM   1853  C  CA   . HIS A 1 244 ? 21.025  -8.462  29.985  1.00 49.34  ? 451 HIS A CA   1 
ATOM   1854  C  C    . HIS A 1 244 ? 20.453  -7.056  29.934  1.00 51.15  ? 451 HIS A C    1 
ATOM   1855  O  O    . HIS A 1 244 ? 19.769  -6.685  30.885  1.00 48.94  ? 451 HIS A O    1 
ATOM   1856  C  CB   . HIS A 1 244 ? 22.475  -8.388  30.449  1.00 50.43  ? 451 HIS A CB   1 
ATOM   1857  C  CG   . HIS A 1 244 ? 22.676  -7.864  31.829  1.00 50.79  ? 451 HIS A CG   1 
ATOM   1858  N  ND1  . HIS A 1 244 ? 23.459  -6.761  32.083  1.00 50.60  ? 451 HIS A ND1  1 
ATOM   1859  C  CD2  . HIS A 1 244 ? 22.247  -8.310  33.026  1.00 52.02  ? 451 HIS A CD2  1 
ATOM   1860  C  CE1  . HIS A 1 244 ? 23.489  -6.538  33.378  1.00 56.41  ? 451 HIS A CE1  1 
ATOM   1861  N  NE2  . HIS A 1 244 ? 22.751  -7.470  33.976  1.00 55.63  ? 451 HIS A NE2  1 
ATOM   1862  N  N    . ALA A 1 245 ? 20.730  -6.310  28.868  1.00 49.77  ? 452 ALA A N    1 
ATOM   1863  C  CA   . ALA A 1 245 ? 20.293  -4.903  28.880  1.00 45.93  ? 452 ALA A CA   1 
ATOM   1864  C  C    . ALA A 1 245 ? 19.827  -4.396  27.523  1.00 46.99  ? 452 ALA A C    1 
ATOM   1865  O  O    . ALA A 1 245 ? 20.380  -4.815  26.508  1.00 55.38  ? 452 ALA A O    1 
ATOM   1866  C  CB   . ALA A 1 245 ? 21.399  -4.043  29.410  1.00 49.22  ? 452 ALA A CB   1 
ATOM   1867  N  N    . VAL A 1 246 ? 18.842  -3.501  27.543  1.00 51.16  ? 453 VAL A N    1 
ATOM   1868  C  CA   . VAL A 1 246 ? 18.317  -2.867  26.304  1.00 49.63  ? 453 VAL A CA   1 
ATOM   1869  C  C    . VAL A 1 246 ? 18.316  -1.357  26.539  1.00 51.36  ? 453 VAL A C    1 
ATOM   1870  O  O    . VAL A 1 246 ? 17.433  -0.875  27.241  1.00 51.25  ? 453 VAL A O    1 
ATOM   1871  C  CB   . VAL A 1 246 ? 16.915  -3.389  25.933  1.00 51.57  ? 453 VAL A CB   1 
ATOM   1872  C  CG1  . VAL A 1 246 ? 16.466  -2.896  24.571  1.00 47.13  ? 453 VAL A CG1  1 
ATOM   1873  C  CG2  . VAL A 1 246 ? 16.800  -4.902  26.017  1.00 45.64  ? 453 VAL A CG2  1 
ATOM   1874  N  N    . LEU A 1 247 ? 19.336  -0.674  26.022  1.00 52.70  ? 454 LEU A N    1 
ATOM   1875  C  CA   . LEU A 1 247 ? 19.422  0.801   26.112  1.00 47.14  ? 454 LEU A CA   1 
ATOM   1876  C  C    . LEU A 1 247 ? 18.522  1.313   25.003  1.00 54.83  ? 454 LEU A C    1 
ATOM   1877  O  O    . LEU A 1 247 ? 18.851  1.107   23.834  1.00 49.74  ? 454 LEU A O    1 
ATOM   1878  C  CB   . LEU A 1 247 ? 20.881  1.242   26.011  1.00 42.60  ? 454 LEU A CB   1 
ATOM   1879  C  CG   . LEU A 1 247 ? 21.745  0.879   27.216  1.00 47.66  ? 454 LEU A CG   1 
ATOM   1880  C  CD1  . LEU A 1 247 ? 22.489  -0.429  27.009  1.00 47.73  ? 454 LEU A CD1  1 
ATOM   1881  C  CD2  . LEU A 1 247 ? 22.715  1.991   27.556  1.00 46.76  ? 454 LEU A CD2  1 
ATOM   1882  N  N    . VAL A 1 248 ? 17.439  1.978   25.374  1.00 54.91  ? 455 VAL A N    1 
ATOM   1883  C  CA   . VAL A 1 248 ? 16.371  2.347   24.459  1.00 51.27  ? 455 VAL A CA   1 
ATOM   1884  C  C    . VAL A 1 248 ? 16.443  3.844   24.245  1.00 49.66  ? 455 VAL A C    1 
ATOM   1885  O  O    . VAL A 1 248 ? 16.579  4.611   25.208  1.00 50.16  ? 455 VAL A O    1 
ATOM   1886  C  CB   . VAL A 1 248 ? 14.996  1.929   25.011  1.00 53.29  ? 455 VAL A CB   1 
ATOM   1887  C  CG1  . VAL A 1 248 ? 13.862  2.435   24.124  1.00 53.30  ? 455 VAL A CG1  1 
ATOM   1888  C  CG2  . VAL A 1 248 ? 14.930  0.428   25.171  1.00 50.34  ? 455 VAL A CG2  1 
ATOM   1889  N  N    . HIS A 1 249 ? 16.368  4.253   22.989  1.00 44.30  ? 456 HIS A N    1 
ATOM   1890  C  CA   . HIS A 1 249 ? 16.377  5.651   22.623  1.00 51.36  ? 456 HIS A CA   1 
ATOM   1891  C  C    . HIS A 1 249 ? 15.035  6.013   21.999  1.00 57.32  ? 456 HIS A C    1 
ATOM   1892  O  O    . HIS A 1 249 ? 14.501  5.287   21.150  1.00 58.94  ? 456 HIS A O    1 
ATOM   1893  C  CB   . HIS A 1 249 ? 17.503  5.962   21.656  1.00 49.68  ? 456 HIS A CB   1 
ATOM   1894  C  CG   . HIS A 1 249 ? 17.389  7.313   21.033  1.00 53.67  ? 456 HIS A CG   1 
ATOM   1895  N  ND1  . HIS A 1 249 ? 16.544  7.571   19.979  1.00 55.97  ? 456 HIS A ND1  1 
ATOM   1896  C  CD2  . HIS A 1 249 ? 18.004  8.486   21.323  1.00 54.28  ? 456 HIS A CD2  1 
ATOM   1897  C  CE1  . HIS A 1 249 ? 16.654  8.842   19.632  1.00 61.20  ? 456 HIS A CE1  1 
ATOM   1898  N  NE2  . HIS A 1 249 ? 17.537  9.417   20.429  1.00 59.26  ? 456 HIS A NE2  1 
ATOM   1899  N  N    . SER A 1 250 ? 14.488  7.136   22.423  1.00 55.38  ? 457 SER A N    1 
ATOM   1900  C  CA   . SER A 1 250 ? 13.215  7.601   21.915  1.00 59.18  ? 457 SER A CA   1 
ATOM   1901  C  C    . SER A 1 250 ? 13.461  8.983   21.367  1.00 54.29  ? 457 SER A C    1 
ATOM   1902  O  O    . SER A 1 250 ? 14.105  9.791   22.028  1.00 58.07  ? 457 SER A O    1 
ATOM   1903  C  CB   . SER A 1 250 ? 12.163  7.637   23.017  1.00 61.14  ? 457 SER A CB   1 
ATOM   1904  O  OG   . SER A 1 250 ? 12.642  8.452   24.072  1.00 67.94  ? 457 SER A OG   1 
ATOM   1905  N  N    . GLY A 1 251 ? 13.012  9.227   20.148  1.00 58.69  ? 458 GLY A N    1 
ATOM   1906  C  CA   . GLY A 1 251 ? 13.139  10.571  19.573  1.00 61.11  ? 458 GLY A CA   1 
ATOM   1907  C  C    . GLY A 1 251 ? 13.748  10.578  18.191  1.00 65.64  ? 458 GLY A C    1 
ATOM   1908  O  O    . GLY A 1 251 ? 13.468  9.659   17.408  1.00 62.79  ? 458 GLY A O    1 
ATOM   1909  N  N    . ASP A 1 252 ? 14.538  11.605  17.904  1.00 68.81  ? 459 ASP A N    1 
ATOM   1910  C  CA   . ASP A 1 252 ? 15.173  11.758  16.578  1.00 71.18  ? 459 ASP A CA   1 
ATOM   1911  C  C    . ASP A 1 252 ? 16.686  11.817  16.753  1.00 74.26  ? 459 ASP A C    1 
ATOM   1912  O  O    . ASP A 1 252 ? 17.173  11.581  17.869  1.00 72.47  ? 459 ASP A O    1 
ATOM   1913  C  CB   . ASP A 1 252 ? 14.691  13.050  15.919  1.00 74.95  ? 459 ASP A CB   1 
ATOM   1914  C  CG   . ASP A 1 252 ? 14.495  12.967  14.416  1.00 86.24  ? 459 ASP A CG   1 
ATOM   1915  O  OD1  . ASP A 1 252 ? 15.169  12.134  13.775  1.00 87.96  ? 459 ASP A OD1  1 
ATOM   1916  O  OD2  . ASP A 1 252 ? 13.677  13.751  13.897  1.00 94.19  ? 459 ASP A OD2  1 
ATOM   1917  N  N    . ASN A 1 253 ? 17.404  12.135  15.683  1.00 76.60  ? 460 ASN A N    1 
ATOM   1918  C  CA   . ASN A 1 253 ? 18.860  12.261  15.734  1.00 68.29  ? 460 ASN A CA   1 
ATOM   1919  C  C    . ASN A 1 253 ? 19.282  13.533  16.469  1.00 81.72  ? 460 ASN A C    1 
ATOM   1920  O  O    . ASN A 1 253 ? 20.276  13.525  17.214  1.00 71.45  ? 460 ASN A O    1 
ATOM   1921  C  CB   . ASN A 1 253 ? 19.447  12.237  14.322  1.00 75.51  ? 460 ASN A CB   1 
ATOM   1922  N  N    . HIS A 1 254 ? 18.535  14.634  16.274  1.00 82.64  ? 461 HIS A N    1 
ATOM   1923  C  CA   . HIS A 1 254 ? 18.787  15.858  17.033  1.00 74.66  ? 461 HIS A CA   1 
ATOM   1924  C  C    . HIS A 1 254 ? 18.678  15.617  18.540  1.00 72.22  ? 461 HIS A C    1 
ATOM   1925  O  O    . HIS A 1 254 ? 19.533  16.065  19.315  1.00 75.31  ? 461 HIS A O    1 
ATOM   1926  N  N    . GLY A 1 255 ? 17.637  14.915  18.979  1.00 66.97  ? 462 GLY A N    1 
ATOM   1927  C  CA   . GLY A 1 255 ? 17.451  14.765  20.414  1.00 70.64  ? 462 GLY A CA   1 
ATOM   1928  C  C    . GLY A 1 255 ? 16.365  13.762  20.754  1.00 67.82  ? 462 GLY A C    1 
ATOM   1929  O  O    . GLY A 1 255 ? 15.688  13.217  19.878  1.00 73.08  ? 462 GLY A O    1 
ATOM   1930  N  N    . GLY A 1 256 ? 16.210  13.525  22.052  1.00 60.42  ? 463 GLY A N    1 
ATOM   1931  C  CA   . GLY A 1 256 ? 15.294  12.487  22.500  1.00 60.15  ? 463 GLY A CA   1 
ATOM   1932  C  C    . GLY A 1 256 ? 15.505  12.157  23.963  1.00 62.48  ? 463 GLY A C    1 
ATOM   1933  O  O    . GLY A 1 256 ? 15.940  13.010  24.751  1.00 63.47  ? 463 GLY A O    1 
ATOM   1934  N  N    . HIS A 1 257 ? 15.202  10.900  24.319  1.00 61.29  ? 464 HIS A N    1 
ATOM   1935  C  CA   . HIS A 1 257 ? 15.312  10.437  25.700  1.00 62.44  ? 464 HIS A CA   1 
ATOM   1936  C  C    . HIS A 1 257 ? 15.881  9.025   25.726  1.00 56.75  ? 464 HIS A C    1 
ATOM   1937  O  O    . HIS A 1 257 ? 15.634  8.237   24.810  1.00 58.69  ? 464 HIS A O    1 
ATOM   1938  C  CB   . HIS A 1 257 ? 13.953  10.462  26.421  1.00 54.90  ? 464 HIS A CB   1 
ATOM   1939  C  CG   . HIS A 1 257 ? 14.048  10.285  27.907  1.00 52.92  ? 464 HIS A CG   1 
ATOM   1940  N  ND1  . HIS A 1 257 ? 14.739  11.157  28.719  1.00 55.76  ? 464 HIS A ND1  1 
ATOM   1941  C  CD2  . HIS A 1 257 ? 13.551  9.326   28.726  1.00 57.17  ? 464 HIS A CD2  1 
ATOM   1942  C  CE1  . HIS A 1 257 ? 14.675  10.738  29.973  1.00 52.67  ? 464 HIS A CE1  1 
ATOM   1943  N  NE2  . HIS A 1 257 ? 13.957  9.630   30.004  1.00 54.06  ? 464 HIS A NE2  1 
ATOM   1944  N  N    . TYR A 1 258 ? 16.637  8.710   26.793  1.00 56.14  ? 465 TYR A N    1 
ATOM   1945  C  CA   . TYR A 1 258 ? 17.238  7.393   27.010  1.00 50.44  ? 465 TYR A CA   1 
ATOM   1946  C  C    . TYR A 1 258 ? 16.672  6.772   28.276  1.00 58.25  ? 465 TYR A C    1 
ATOM   1947  O  O    . TYR A 1 258 ? 16.571  7.432   29.317  1.00 60.58  ? 465 TYR A O    1 
ATOM   1948  C  CB   . TYR A 1 258 ? 18.772  7.459   27.149  1.00 50.94  ? 465 TYR A CB   1 
ATOM   1949  C  CG   . TYR A 1 258 ? 19.546  7.442   25.838  1.00 57.18  ? 465 TYR A CG   1 
ATOM   1950  C  CD1  . TYR A 1 258 ? 19.813  6.239   25.173  1.00 49.41  ? 465 TYR A CD1  1 
ATOM   1951  C  CD2  . TYR A 1 258 ? 20.009  8.624   25.261  1.00 53.90  ? 465 TYR A CD2  1 
ATOM   1952  C  CE1  . TYR A 1 258 ? 20.511  6.211   23.971  1.00 49.27  ? 465 TYR A CE1  1 
ATOM   1953  C  CE2  . TYR A 1 258 ? 20.737  8.603   24.048  1.00 57.63  ? 465 TYR A CE2  1 
ATOM   1954  C  CZ   . TYR A 1 258 ? 20.981  7.385   23.420  1.00 54.54  ? 465 TYR A CZ   1 
ATOM   1955  O  OH   . TYR A 1 258 ? 21.670  7.343   22.229  1.00 50.50  ? 465 TYR A OH   1 
ATOM   1956  N  N    . VAL A 1 259 ? 16.302  5.504   28.185  1.00 57.45  ? 466 VAL A N    1 
ATOM   1957  C  CA   . VAL A 1 259 ? 16.065  4.667   29.345  1.00 56.94  ? 466 VAL A CA   1 
ATOM   1958  C  C    . VAL A 1 259 ? 16.784  3.358   29.056  1.00 58.77  ? 466 VAL A C    1 
ATOM   1959  O  O    . VAL A 1 259 ? 17.228  3.108   27.935  1.00 56.17  ? 466 VAL A O    1 
ATOM   1960  C  CB   . VAL A 1 259 ? 14.558  4.436   29.612  1.00 60.48  ? 466 VAL A CB   1 
ATOM   1961  C  CG1  . VAL A 1 259 ? 13.770  5.758   29.505  1.00 58.16  ? 466 VAL A CG1  1 
ATOM   1962  C  CG2  . VAL A 1 259 ? 13.985  3.398   28.626  1.00 59.18  ? 466 VAL A CG2  1 
ATOM   1963  N  N    . VAL A 1 260 ? 16.901  2.514   30.066  1.00 51.78  ? 467 VAL A N    1 
ATOM   1964  C  CA   . VAL A 1 260 ? 17.512  1.216   29.849  1.00 53.51  ? 467 VAL A CA   1 
ATOM   1965  C  C    . VAL A 1 260 ? 16.712  0.180   30.622  1.00 59.61  ? 467 VAL A C    1 
ATOM   1966  O  O    . VAL A 1 260 ? 16.307  0.412   31.768  1.00 58.37  ? 467 VAL A O    1 
ATOM   1967  C  CB   . VAL A 1 260 ? 19.012  1.210   30.238  1.00 53.69  ? 467 VAL A CB   1 
ATOM   1968  C  CG1  . VAL A 1 260 ? 19.215  1.621   31.709  1.00 53.17  ? 467 VAL A CG1  1 
ATOM   1969  C  CG2  . VAL A 1 260 ? 19.620  -0.162  29.981  1.00 53.13  ? 467 VAL A CG2  1 
ATOM   1970  N  N    . TYR A 1 261 ? 16.451  -0.952  29.976  1.00 59.37  ? 468 TYR A N    1 
ATOM   1971  C  CA   . TYR A 1 261 ? 15.830  -2.095  30.628  1.00 54.79  ? 468 TYR A CA   1 
ATOM   1972  C  C    . TYR A 1 261 ? 16.903  -3.117  30.942  1.00 51.32  ? 468 TYR A C    1 
ATOM   1973  O  O    . TYR A 1 261 ? 17.762  -3.389  30.106  1.00 51.49  ? 468 TYR A O    1 
ATOM   1974  C  CB   . TYR A 1 261 ? 14.772  -2.742  29.739  1.00 55.88  ? 468 TYR A CB   1 
ATOM   1975  C  CG   . TYR A 1 261 ? 13.599  -1.858  29.383  1.00 61.92  ? 468 TYR A CG   1 
ATOM   1976  C  CD1  . TYR A 1 261 ? 13.759  -0.745  28.557  1.00 53.78  ? 468 TYR A CD1  1 
ATOM   1977  C  CD2  . TYR A 1 261 ? 12.315  -2.155  29.853  1.00 59.91  ? 468 TYR A CD2  1 
ATOM   1978  C  CE1  . TYR A 1 261 ? 12.681  0.044   28.224  1.00 54.68  ? 468 TYR A CE1  1 
ATOM   1979  C  CE2  . TYR A 1 261 ? 11.241  -1.364  29.525  1.00 55.08  ? 468 TYR A CE2  1 
ATOM   1980  C  CZ   . TYR A 1 261 ? 11.429  -0.271  28.720  1.00 53.40  ? 468 TYR A CZ   1 
ATOM   1981  O  OH   . TYR A 1 261 ? 10.355  0.503   28.394  1.00 58.13  ? 468 TYR A OH   1 
ATOM   1982  N  N    . LEU A 1 262 ? 16.834  -3.664  32.151  1.00 53.05  ? 469 LEU A N    1 
ATOM   1983  C  CA   . LEU A 1 262 ? 17.864  -4.620  32.608  1.00 51.57  ? 469 LEU A CA   1 
ATOM   1984  C  C    . LEU A 1 262 ? 17.243  -5.742  33.429  1.00 50.18  ? 469 LEU A C    1 
ATOM   1985  O  O    . LEU A 1 262 ? 16.273  -5.473  34.139  1.00 56.20  ? 469 LEU A O    1 
ATOM   1986  C  CB   . LEU A 1 262 ? 18.859  -3.874  33.505  1.00 49.64  ? 469 LEU A CB   1 
ATOM   1987  C  CG   . LEU A 1 262 ? 19.979  -3.078  32.849  1.00 51.38  ? 469 LEU A CG   1 
ATOM   1988  C  CD1  . LEU A 1 262 ? 19.989  -1.665  33.392  1.00 50.46  ? 469 LEU A CD1  1 
ATOM   1989  C  CD2  . LEU A 1 262 ? 21.316  -3.733  33.132  1.00 47.69  ? 469 LEU A CD2  1 
ATOM   1990  N  N    . ASN A 1 263 ? 17.734  -6.962  33.271  1.00 51.72  ? 470 ASN A N    1 
ATOM   1991  C  CA   . ASN A 1 263 ? 17.366  -8.076  34.181  1.00 60.11  ? 470 ASN A CA   1 
ATOM   1992  C  C    . ASN A 1 263 ? 18.649  -8.215  34.995  1.00 57.04  ? 470 ASN A C    1 
ATOM   1993  O  O    . ASN A 1 263 ? 19.483  -9.042  34.648  1.00 53.28  ? 470 ASN A O    1 
ATOM   1994  C  CB   . ASN A 1 263 ? 16.794  -9.315  33.472  1.00 57.24  ? 470 ASN A CB   1 
ATOM   1995  C  CG   . ASN A 1 263 ? 17.706  -10.071 32.534  1.00 56.57  ? 470 ASN A CG   1 
ATOM   1996  O  OD1  . ASN A 1 263 ? 17.834  -11.283 32.644  1.00 57.96  ? 470 ASN A OD1  1 
ATOM   1997  N  ND2  . ASN A 1 263 ? 18.305  -9.380  31.587  1.00 50.08  ? 470 ASN A ND2  1 
ATOM   1998  N  N    . PRO A 1 264 ? 18.855  -7.407  36.054  1.00 61.32  ? 471 PRO A N    1 
ATOM   1999  C  CA   . PRO A 1 264 ? 20.154  -7.348  36.728  1.00 52.56  ? 471 PRO A CA   1 
ATOM   2000  C  C    . PRO A 1 264 ? 20.795  -8.694  37.055  1.00 57.97  ? 471 PRO A C    1 
ATOM   2001  O  O    . PRO A 1 264 ? 21.977  -8.812  36.872  1.00 56.20  ? 471 PRO A O    1 
ATOM   2002  C  CB   . PRO A 1 264 ? 19.801  -6.553  37.981  1.00 53.76  ? 471 PRO A CB   1 
ATOM   2003  C  CG   . PRO A 1 264 ? 18.734  -5.625  37.494  1.00 58.67  ? 471 PRO A CG   1 
ATOM   2004  C  CD   . PRO A 1 264 ? 17.853  -6.572  36.718  1.00 55.49  ? 471 PRO A CD   1 
ATOM   2005  N  N    . LYS A 1 265 ? 20.003  -9.654  37.510  1.00 64.11  ? 472 LYS A N    1 
ATOM   2006  C  CA   . LYS A 1 265 ? 20.594  -10.941 37.957  1.00 65.63  ? 472 LYS A CA   1 
ATOM   2007  C  C    . LYS A 1 265 ? 20.677  -11.916 36.790  1.00 59.55  ? 472 LYS A C    1 
ATOM   2008  O  O    . LYS A 1 265 ? 21.148  -13.041 37.008  1.00 62.45  ? 472 LYS A O    1 
ATOM   2009  C  CB   . LYS A 1 265 ? 19.764  -11.515 39.107  1.00 65.91  ? 472 LYS A CB   1 
ATOM   2010  C  CG   . LYS A 1 265 ? 19.201  -10.487 40.080  1.00 68.21  ? 472 LYS A CG   1 
ATOM   2011  C  CD   . LYS A 1 265 ? 18.853  -11.063 41.433  1.00 69.32  ? 472 LYS A CD   1 
ATOM   2012  N  N    . GLY A 1 266 ? 20.280  -11.485 35.596  1.00 57.96  ? 473 GLY A N    1 
ATOM   2013  C  CA   . GLY A 1 266 ? 20.259  -12.421 34.485  1.00 63.94  ? 473 GLY A CA   1 
ATOM   2014  C  C    . GLY A 1 266 ? 19.230  -13.523 34.625  1.00 65.82  ? 473 GLY A C    1 
ATOM   2015  O  O    . GLY A 1 266 ? 19.368  -14.576 33.994  1.00 62.93  ? 473 GLY A O    1 
ATOM   2016  N  N    . ASP A 1 267 ? 18.194  -13.297 35.437  1.00 67.32  ? 474 ASP A N    1 
ATOM   2017  C  CA   . ASP A 1 267 ? 17.214  -14.301 35.824  1.00 64.34  ? 474 ASP A CA   1 
ATOM   2018  C  C    . ASP A 1 267 ? 15.894  -14.157 35.078  1.00 69.19  ? 474 ASP A C    1 
ATOM   2019  O  O    . ASP A 1 267 ? 14.944  -14.894 35.368  1.00 76.82  ? 474 ASP A O    1 
ATOM   2020  C  CB   . ASP A 1 267 ? 16.960  -14.209 37.323  1.00 59.60  ? 474 ASP A CB   1 
ATOM   2021  C  CG   . ASP A 1 267 ? 16.491  -12.834 37.736  1.00 69.56  ? 474 ASP A CG   1 
ATOM   2022  O  OD1  . ASP A 1 267 ? 16.364  -11.961 36.843  1.00 66.40  ? 474 ASP A OD1  1 
ATOM   2023  O  OD2  . ASP A 1 267 ? 16.261  -12.615 38.949  1.00 73.49  ? 474 ASP A OD2  1 
ATOM   2024  N  N    . GLY A 1 268 ? 15.805  -13.228 34.138  1.00 65.78  ? 475 GLY A N    1 
ATOM   2025  C  CA   . GLY A 1 268 ? 14.572  -12.999 33.427  1.00 62.86  ? 475 GLY A CA   1 
ATOM   2026  C  C    . GLY A 1 268 ? 13.609  -12.078 34.123  1.00 60.46  ? 475 GLY A C    1 
ATOM   2027  O  O    . GLY A 1 268 ? 12.544  -11.795 33.561  1.00 61.34  ? 475 GLY A O    1 
ATOM   2028  N  N    . LYS A 1 269 ? 13.946  -11.597 35.323  1.00 63.08  ? 476 LYS A N    1 
ATOM   2029  C  CA   . LYS A 1 269 ? 13.117  -10.638 36.054  1.00 63.63  ? 476 LYS A CA   1 
ATOM   2030  C  C    . LYS A 1 269 ? 13.589  -9.231  35.705  1.00 62.41  ? 476 LYS A C    1 
ATOM   2031  O  O    . LYS A 1 269 ? 14.694  -8.830  36.084  1.00 65.88  ? 476 LYS A O    1 
ATOM   2032  C  CB   . LYS A 1 269 ? 13.199  -10.891 37.559  1.00 64.21  ? 476 LYS A CB   1 
ATOM   2033  N  N    . TRP A 1 270 ? 12.745  -8.466  35.025  1.00 57.89  ? 477 TRP A N    1 
ATOM   2034  C  CA   . TRP A 1 270 ? 13.163  -7.237  34.369  1.00 57.93  ? 477 TRP A CA   1 
ATOM   2035  C  C    . TRP A 1 270 ? 12.654  -5.998  35.085  1.00 59.52  ? 477 TRP A C    1 
ATOM   2036  O  O    . TRP A 1 270 ? 11.522  -5.958  35.571  1.00 62.00  ? 477 TRP A O    1 
ATOM   2037  C  CB   . TRP A 1 270 ? 12.658  -7.197  32.923  1.00 56.49  ? 477 TRP A CB   1 
ATOM   2038  C  CG   . TRP A 1 270 ? 13.455  -8.062  31.977  1.00 63.68  ? 477 TRP A CG   1 
ATOM   2039  C  CD1  . TRP A 1 270 ? 13.357  -9.425  31.817  1.00 62.02  ? 477 TRP A CD1  1 
ATOM   2040  C  CD2  . TRP A 1 270 ? 14.478  -7.624  31.072  1.00 59.45  ? 477 TRP A CD2  1 
ATOM   2041  N  NE1  . TRP A 1 270 ? 14.253  -9.853  30.860  1.00 64.50  ? 477 TRP A NE1  1 
ATOM   2042  C  CE2  . TRP A 1 270 ? 14.951  -8.769  30.385  1.00 63.29  ? 477 TRP A CE2  1 
ATOM   2043  C  CE3  . TRP A 1 270 ? 15.042  -6.378  30.776  1.00 55.61  ? 477 TRP A CE3  1 
ATOM   2044  C  CZ2  . TRP A 1 270 ? 15.956  -8.699  29.415  1.00 54.32  ? 477 TRP A CZ2  1 
ATOM   2045  C  CZ3  . TRP A 1 270 ? 16.034  -6.314  29.814  1.00 55.53  ? 477 TRP A CZ3  1 
ATOM   2046  C  CH2  . TRP A 1 270 ? 16.482  -7.471  29.146  1.00 50.04  ? 477 TRP A CH2  1 
ATOM   2047  N  N    . CYS A 1 271 ? 13.474  -4.957  35.088  1.00 57.70  ? 478 CYS A N    1 
ATOM   2048  C  CA   . CYS A 1 271 ? 12.993  -3.636  35.459  1.00 57.70  ? 478 CYS A CA   1 
ATOM   2049  C  C    . CYS A 1 271 ? 13.320  -2.628  34.362  1.00 59.53  ? 478 CYS A C    1 
ATOM   2050  O  O    . CYS A 1 271 ? 14.048  -2.902  33.404  1.00 58.32  ? 478 CYS A O    1 
ATOM   2051  C  CB   . CYS A 1 271 ? 13.571  -3.170  36.804  1.00 52.87  ? 478 CYS A CB   1 
ATOM   2052  S  SG   . CYS A 1 271 ? 13.236  -4.318  38.124  1.00 58.58  ? 478 CYS A SG   1 
ATOM   2053  N  N    . LYS A 1 272 ? 12.689  -1.460  34.506  1.00 59.79  ? 479 LYS A N    1 
ATOM   2054  C  CA   . LYS A 1 272 ? 12.911  -0.322  33.589  1.00 61.62  ? 479 LYS A CA   1 
ATOM   2055  C  C    . LYS A 1 272 ? 13.502  0.794   34.431  1.00 63.83  ? 479 LYS A C    1 
ATOM   2056  O  O    . LYS A 1 272 ? 13.044  0.965   35.550  1.00 64.84  ? 479 LYS A O    1 
ATOM   2057  C  CB   . LYS A 1 272 ? 11.599  0.177   32.985  1.00 55.53  ? 479 LYS A CB   1 
ATOM   2058  C  CG   . LYS A 1 272 ? 11.702  1.401   32.090  1.00 56.13  ? 479 LYS A CG   1 
ATOM   2059  C  CD   . LYS A 1 272 ? 10.375  2.084   31.880  1.00 59.12  ? 479 LYS A CD   1 
ATOM   2060  C  CE   . LYS A 1 272 ? 10.486  3.335   31.039  1.00 56.08  ? 479 LYS A CE   1 
ATOM   2061  N  NZ   . LYS A 1 272 ? 9.396   3.416   30.040  1.00 65.91  ? 479 LYS A NZ   1 
ATOM   2062  N  N    . PHE A 1 273 ? 14.477  1.512   33.875  1.00 65.40  ? 480 PHE A N    1 
ATOM   2063  C  CA   . PHE A 1 273 ? 15.189  2.577   34.617  1.00 61.55  ? 480 PHE A CA   1 
ATOM   2064  C  C    . PHE A 1 273 ? 15.054  3.874   33.826  1.00 57.02  ? 480 PHE A C    1 
ATOM   2065  O  O    . PHE A 1 273 ? 15.896  4.123   32.956  1.00 58.42  ? 480 PHE A O    1 
ATOM   2066  C  CB   . PHE A 1 273 ? 16.649  2.168   34.838  1.00 62.32  ? 480 PHE A CB   1 
ATOM   2067  C  CG   . PHE A 1 273 ? 16.882  0.887   35.601  1.00 59.17  ? 480 PHE A CG   1 
ATOM   2068  C  CD1  . PHE A 1 273 ? 16.676  -0.352  35.015  1.00 55.64  ? 480 PHE A CD1  1 
ATOM   2069  C  CD2  . PHE A 1 273 ? 17.353  0.921   36.900  1.00 57.25  ? 480 PHE A CD2  1 
ATOM   2070  C  CE1  . PHE A 1 273 ? 16.887  -1.522  35.723  1.00 55.15  ? 480 PHE A CE1  1 
ATOM   2071  C  CE2  . PHE A 1 273 ? 17.575  -0.249  37.606  1.00 60.82  ? 480 PHE A CE2  1 
ATOM   2072  C  CZ   . PHE A 1 273 ? 17.340  -1.468  37.017  1.00 57.74  ? 480 PHE A CZ   1 
ATOM   2073  N  N    . ASP A 1 274 ? 14.001  4.639   34.101  1.00 59.28  ? 481 ASP A N    1 
ATOM   2074  C  CA   . ASP A 1 274 ? 13.782  5.947   33.437  1.00 62.85  ? 481 ASP A CA   1 
ATOM   2075  C  C    . ASP A 1 274 ? 14.274  7.011   34.408  1.00 67.13  ? 481 ASP A C    1 
ATOM   2076  O  O    . ASP A 1 274 ? 13.432  7.600   35.110  1.00 71.20  ? 481 ASP A O    1 
ATOM   2077  C  CB   . ASP A 1 274 ? 12.311  6.128   33.053  1.00 62.80  ? 481 ASP A CB   1 
ATOM   2078  C  CG   . ASP A 1 274 ? 11.982  7.305   32.154  1.00 67.56  ? 481 ASP A CG   1 
ATOM   2079  O  OD1  . ASP A 1 274 ? 12.689  8.317   32.221  1.00 60.92  ? 481 ASP A OD1  1 
ATOM   2080  O  OD2  . ASP A 1 274 ? 10.996  7.201   31.406  1.00 61.64  ? 481 ASP A OD2  1 
ATOM   2081  N  N    . ASP A 1 275 ? 15.585  7.208   34.464  1.00 61.53  ? 482 ASP A N    1 
ATOM   2082  C  CA   . ASP A 1 275 ? 16.190  8.223   35.361  1.00 61.63  ? 482 ASP A CA   1 
ATOM   2083  C  C    . ASP A 1 275 ? 15.797  7.922   36.812  1.00 68.10  ? 482 ASP A C    1 
ATOM   2084  O  O    . ASP A 1 275 ? 16.249  6.893   37.319  1.00 66.09  ? 482 ASP A O    1 
ATOM   2085  C  CB   . ASP A 1 275 ? 15.888  9.647   34.877  1.00 62.36  ? 482 ASP A CB   1 
ATOM   2086  C  CG   . ASP A 1 275 ? 16.651  10.053  33.636  1.00 56.58  ? 482 ASP A CG   1 
ATOM   2087  O  OD1  . ASP A 1 275 ? 17.743  9.516   33.423  1.00 54.51  ? 482 ASP A OD1  1 
ATOM   2088  O  OD2  . ASP A 1 275 ? 16.143  10.909  32.903  1.00 59.10  ? 482 ASP A OD2  1 
ATOM   2089  N  N    . ASP A 1 276 ? 14.987  8.768   37.446  1.00 65.75  ? 483 ASP A N    1 
ATOM   2090  C  CA   . ASP A 1 276 ? 14.680  8.627   38.897  1.00 64.38  ? 483 ASP A CA   1 
ATOM   2091  C  C    . ASP A 1 276 ? 13.738  7.464   39.205  1.00 68.21  ? 483 ASP A C    1 
ATOM   2092  O  O    . ASP A 1 276 ? 13.695  7.056   40.373  1.00 66.21  ? 483 ASP A O    1 
ATOM   2093  C  CB   . ASP A 1 276 ? 14.122  9.944   39.445  1.00 53.81  ? 483 ASP A CB   1 
ATOM   2094  C  CG   . ASP A 1 276 ? 12.934  10.524  38.700  1.00 65.27  ? 483 ASP A CG   1 
ATOM   2095  O  OD1  . ASP A 1 276 ? 12.976  10.584  37.460  1.00 67.54  ? 483 ASP A OD1  1 
ATOM   2096  O  OD2  . ASP A 1 276 ? 11.980  10.939  39.379  1.00 66.63  ? 483 ASP A OD2  1 
ATOM   2097  N  N    . VAL A 1 277 ? 13.059  6.910   38.210  1.00 65.90  ? 484 VAL A N    1 
ATOM   2098  C  CA   . VAL A 1 277 ? 12.022  5.909   38.447  1.00 66.02  ? 484 VAL A CA   1 
ATOM   2099  C  C    . VAL A 1 277 ? 12.466  4.570   37.874  1.00 63.49  ? 484 VAL A C    1 
ATOM   2100  O  O    . VAL A 1 277 ? 12.644  4.431   36.656  1.00 60.27  ? 484 VAL A O    1 
ATOM   2101  C  CB   . VAL A 1 277 ? 10.675  6.328   37.839  1.00 66.97  ? 484 VAL A CB   1 
ATOM   2102  C  CG1  . VAL A 1 277 ? 9.539   5.527   38.477  1.00 69.60  ? 484 VAL A CG1  1 
ATOM   2103  C  CG2  . VAL A 1 277 ? 10.459  7.827   37.983  1.00 61.17  ? 484 VAL A CG2  1 
ATOM   2104  N  N    . VAL A 1 278 ? 12.550  3.603   38.782  1.00 64.88  ? 485 VAL A N    1 
ATOM   2105  C  CA   . VAL A 1 278 ? 12.783  2.197   38.378  1.00 64.85  ? 485 VAL A CA   1 
ATOM   2106  C  C    . VAL A 1 278 ? 11.429  1.515   38.570  1.00 67.51  ? 485 VAL A C    1 
ATOM   2107  O  O    . VAL A 1 278 ? 10.730  1.869   39.530  1.00 70.59  ? 485 VAL A O    1 
ATOM   2108  C  CB   . VAL A 1 278 ? 13.872  1.535   39.232  1.00 64.90  ? 485 VAL A CB   1 
ATOM   2109  C  CG1  . VAL A 1 278 ? 14.177  0.117   38.786  1.00 59.41  ? 485 VAL A CG1  1 
ATOM   2110  C  CG2  . VAL A 1 278 ? 15.130  2.371   39.271  1.00 62.34  ? 485 VAL A CG2  1 
ATOM   2111  N  N    . SER A 1 279 ? 11.058  0.601   37.685  1.00 66.05  ? 486 SER A N    1 
ATOM   2112  C  CA   . SER A 1 279 ? 9.751   -0.052  37.737  1.00 66.58  ? 486 SER A CA   1 
ATOM   2113  C  C    . SER A 1 279 ? 9.841   -1.434  37.120  1.00 62.83  ? 486 SER A C    1 
ATOM   2114  O  O    . SER A 1 279 ? 10.418  -1.582  36.043  1.00 66.95  ? 486 SER A O    1 
ATOM   2115  C  CB   . SER A 1 279 ? 8.692   0.764   36.990  1.00 60.01  ? 486 SER A CB   1 
ATOM   2116  O  OG   . SER A 1 279 ? 9.254   1.412   35.859  1.00 68.52  ? 486 SER A OG   1 
ATOM   2117  N  N    . ARG A 1 280 ? 9.260   -2.431  37.787  1.00 60.75  ? 487 ARG A N    1 
ATOM   2118  C  CA   . ARG A 1 280 ? 9.204   -3.766  37.214  1.00 58.73  ? 487 ARG A CA   1 
ATOM   2119  C  C    . ARG A 1 280 ? 8.461   -3.730  35.879  1.00 66.51  ? 487 ARG A C    1 
ATOM   2120  O  O    . ARG A 1 280 ? 7.648   -2.834  35.617  1.00 62.17  ? 487 ARG A O    1 
ATOM   2121  C  CB   . ARG A 1 280 ? 8.533   -4.736  38.190  1.00 61.72  ? 487 ARG A CB   1 
ATOM   2122  C  CG   . ARG A 1 280 ? 9.497   -5.378  39.198  1.00 54.34  ? 487 ARG A CG   1 
ATOM   2123  N  N    . CYS A 1 281 ? 8.781   -4.689  35.011  1.00 57.95  ? 488 CYS A N    1 
ATOM   2124  C  CA   . CYS A 1 281 ? 8.219   -4.727  33.667  1.00 56.98  ? 488 CYS A CA   1 
ATOM   2125  C  C    . CYS A 1 281 ? 8.270   -6.174  33.191  1.00 62.48  ? 488 CYS A C    1 
ATOM   2126  O  O    . CYS A 1 281 ? 8.922   -7.032  33.801  1.00 59.23  ? 488 CYS A O    1 
ATOM   2127  C  CB   . CYS A 1 281 ? 8.982   -3.798  32.707  1.00 61.26  ? 488 CYS A CB   1 
ATOM   2128  S  SG   . CYS A 1 281 ? 10.637  -4.425  32.206  1.00 63.46  ? 488 CYS A SG   1 
ATOM   2129  N  N    . THR A 1 282 ? 7.577   -6.446  32.094  1.00 57.71  ? 489 THR A N    1 
ATOM   2130  C  CA   . THR A 1 282 ? 7.628   -7.808  31.591  1.00 63.48  ? 489 THR A CA   1 
ATOM   2131  C  C    . THR A 1 282 ? 8.745   -7.949  30.563  1.00 62.05  ? 489 THR A C    1 
ATOM   2132  O  O    . THR A 1 282 ? 9.271   -6.964  30.036  1.00 59.06  ? 489 THR A O    1 
ATOM   2133  C  CB   . THR A 1 282 ? 6.296   -8.217  30.967  1.00 61.83  ? 489 THR A CB   1 
ATOM   2134  O  OG1  . THR A 1 282 ? 6.069   -7.426  29.800  1.00 62.47  ? 489 THR A OG1  1 
ATOM   2135  C  CG2  . THR A 1 282 ? 5.154   -8.001  31.952  1.00 59.18  ? 489 THR A CG2  1 
ATOM   2136  N  N    . LYS A 1 283 ? 9.116   -9.205  30.301  1.00 60.99  ? 490 LYS A N    1 
ATOM   2137  C  CA   . LYS A 1 283 ? 9.988   -9.502  29.174  1.00 56.73  ? 490 LYS A CA   1 
ATOM   2138  C  C    . LYS A 1 283 ? 9.446   -8.876  27.905  1.00 60.77  ? 490 LYS A C    1 
ATOM   2139  O  O    . LYS A 1 283 ? 10.174  -8.199  27.169  1.00 60.51  ? 490 LYS A O    1 
ATOM   2140  C  CB   . LYS A 1 283 ? 10.127  -11.007 29.002  1.00 55.70  ? 490 LYS A CB   1 
ATOM   2141  C  CG   . LYS A 1 283 ? 10.914  -11.670 30.088  1.00 59.89  ? 490 LYS A CG   1 
ATOM   2142  C  CD   . LYS A 1 283 ? 11.032  -13.173 29.834  1.00 55.30  ? 490 LYS A CD   1 
ATOM   2143  C  CE   . LYS A 1 283 ? 11.699  -13.850 31.030  1.00 57.40  ? 490 LYS A CE   1 
ATOM   2144  N  NZ   . LYS A 1 283 ? 12.782  -14.789 30.596  1.00 62.27  ? 490 LYS A NZ   1 
ATOM   2145  N  N    . GLU A 1 284 ? 8.151   -9.073  27.650  1.00 62.40  ? 491 GLU A N    1 
ATOM   2146  C  CA   . GLU A 1 284 ? 7.524   -8.486  26.471  1.00 63.68  ? 491 GLU A CA   1 
ATOM   2147  C  C    . GLU A 1 284 ? 7.774   -6.979  26.380  1.00 58.93  ? 491 GLU A C    1 
ATOM   2148  O  O    . GLU A 1 284 ? 7.931   -6.425  25.284  1.00 59.05  ? 491 GLU A O    1 
ATOM   2149  C  CB   . GLU A 1 284 ? 6.028   -8.785  26.489  1.00 65.32  ? 491 GLU A CB   1 
ATOM   2150  C  CG   . GLU A 1 284 ? 5.260   -7.982  25.478  1.00 69.98  ? 491 GLU A CG   1 
ATOM   2151  C  CD   . GLU A 1 284 ? 3.823   -8.407  25.344  1.00 69.48  ? 491 GLU A CD   1 
ATOM   2152  O  OE1  . GLU A 1 284 ? 2.938   -7.643  25.783  1.00 75.03  ? 491 GLU A OE1  1 
ATOM   2153  O  OE2  . GLU A 1 284 ? 3.590   -9.500  24.796  1.00 72.59  ? 491 GLU A OE2  1 
ATOM   2154  N  N    . GLU A 1 285 ? 7.844   -6.298  27.515  1.00 57.13  ? 492 GLU A N    1 
ATOM   2155  C  CA   . GLU A 1 285 ? 8.019   -4.852  27.469  1.00 59.77  ? 492 GLU A CA   1 
ATOM   2156  C  C    . GLU A 1 285 ? 9.466   -4.420  27.283  1.00 58.48  ? 492 GLU A C    1 
ATOM   2157  O  O    . GLU A 1 285 ? 9.707   -3.293  26.833  1.00 53.90  ? 492 GLU A O    1 
ATOM   2158  C  CB   . GLU A 1 285 ? 7.517   -4.221  28.750  1.00 60.17  ? 492 GLU A CB   1 
ATOM   2159  C  CG   . GLU A 1 285 ? 6.052   -4.230  28.923  1.00 59.14  ? 492 GLU A CG   1 
ATOM   2160  C  CD   . GLU A 1 285 ? 5.730   -3.839  30.325  1.00 65.30  ? 492 GLU A CD   1 
ATOM   2161  O  OE1  . GLU A 1 285 ? 6.063   -4.633  31.243  1.00 63.22  ? 492 GLU A OE1  1 
ATOM   2162  O  OE2  . GLU A 1 285 ? 5.202   -2.716  30.499  1.00 68.34  ? 492 GLU A OE2  1 
ATOM   2163  N  N    . ALA A 1 286 ? 10.402  -5.308  27.583  1.00 53.72  ? 493 ALA A N    1 
ATOM   2164  C  CA   . ALA A 1 286 ? 11.834  -4.977  27.475  1.00 58.67  ? 493 ALA A CA   1 
ATOM   2165  C  C    . ALA A 1 286 ? 12.379  -5.402  26.120  1.00 57.40  ? 493 ALA A C    1 
ATOM   2166  O  O    . ALA A 1 286 ? 13.329  -4.777  25.651  1.00 55.01  ? 493 ALA A O    1 
ATOM   2167  C  CB   . ALA A 1 286 ? 12.549  -5.713  28.558  1.00 54.01  ? 493 ALA A CB   1 
ATOM   2168  N  N    . ILE A 1 287 ? 11.791  -6.432  25.527  1.00 54.23  ? 494 ILE A N    1 
ATOM   2169  C  CA   . ILE A 1 287 ? 12.341  -6.991  24.267  1.00 49.80  ? 494 ILE A CA   1 
ATOM   2170  C  C    . ILE A 1 287 ? 11.409  -6.654  23.108  1.00 52.35  ? 494 ILE A C    1 
ATOM   2171  O  O    . ILE A 1 287 ? 11.730  -5.719  22.386  1.00 54.29  ? 494 ILE A O    1 
ATOM   2172  C  CB   . ILE A 1 287 ? 12.560  -8.508  24.447  1.00 53.76  ? 494 ILE A CB   1 
ATOM   2173  C  CG1  . ILE A 1 287 ? 13.352  -8.814  25.722  1.00 51.88  ? 494 ILE A CG1  1 
ATOM   2174  C  CG2  . ILE A 1 287 ? 13.213  -9.134  23.230  1.00 49.07  ? 494 ILE A CG2  1 
ATOM   2175  C  CD1  . ILE A 1 287 ? 13.238  -10.240 26.196  1.00 54.45  ? 494 ILE A CD1  1 
ATOM   2176  N  N    . GLU A 1 288 ? 10.289  -7.356  22.975  1.00 54.86  ? 495 GLU A N    1 
ATOM   2177  C  CA   . GLU A 1 288 ? 9.393   -7.188  21.803  1.00 52.09  ? 495 GLU A CA   1 
ATOM   2178  C  C    . GLU A 1 288 ? 8.948   -5.729  21.629  1.00 53.95  ? 495 GLU A C    1 
ATOM   2179  O  O    . GLU A 1 288 ? 8.891   -5.279  20.485  1.00 56.41  ? 495 GLU A O    1 
ATOM   2180  C  CB   . GLU A 1 288 ? 8.241   -8.179  21.933  1.00 50.81  ? 495 GLU A CB   1 
ATOM   2181  C  CG   . GLU A 1 288 ? 8.613   -9.593  21.538  1.00 55.69  ? 495 GLU A CG   1 
ATOM   2182  C  CD   . GLU A 1 288 ? 9.135   -10.492 22.645  1.00 57.96  ? 495 GLU A CD   1 
ATOM   2183  O  OE1  . GLU A 1 288 ? 9.189   -10.047 23.805  1.00 61.97  ? 495 GLU A OE1  1 
ATOM   2184  O  OE2  . GLU A 1 288 ? 9.489   -11.639 22.339  1.00 60.89  ? 495 GLU A OE2  1 
ATOM   2185  N  N    . HIS A 1 289 ? 8.623   -5.033  22.714  1.00 50.14  ? 496 HIS A N    1 
ATOM   2186  C  CA   . HIS A 1 289 ? 8.163   -3.656  22.579  1.00 56.36  ? 496 HIS A CA   1 
ATOM   2187  C  C    . HIS A 1 289 ? 9.272   -2.703  22.146  1.00 58.79  ? 496 HIS A C    1 
ATOM   2188  O  O    . HIS A 1 289 ? 8.978   -1.572  21.736  1.00 53.86  ? 496 HIS A O    1 
ATOM   2189  C  CB   . HIS A 1 289 ? 7.536   -3.184  23.897  1.00 56.04  ? 496 HIS A CB   1 
ATOM   2190  C  CG   . HIS A 1 289 ? 6.229   -3.845  24.212  1.00 62.72  ? 496 HIS A CG   1 
ATOM   2191  N  ND1  . HIS A 1 289 ? 5.266   -3.254  25.001  1.00 67.44  ? 496 HIS A ND1  1 
ATOM   2192  C  CD2  . HIS A 1 289 ? 5.717   -5.041  23.829  1.00 60.79  ? 496 HIS A CD2  1 
ATOM   2193  C  CE1  . HIS A 1 289 ? 4.223   -4.061  25.099  1.00 64.43  ? 496 HIS A CE1  1 
ATOM   2194  N  NE2  . HIS A 1 289 ? 4.473   -5.153  24.400  1.00 62.71  ? 496 HIS A NE2  1 
ATOM   2195  N  N    . ASN A 1 290 ? 10.533  -3.133  22.196  1.00 53.18  ? 497 ASN A N    1 
ATOM   2196  C  CA   . ASN A 1 290 ? 11.629  -2.289  21.754  1.00 56.82  ? 497 ASN A CA   1 
ATOM   2197  C  C    . ASN A 1 290 ? 12.136  -2.658  20.367  1.00 57.70  ? 497 ASN A C    1 
ATOM   2198  O  O    . ASN A 1 290 ? 13.162  -2.120  19.921  1.00 55.00  ? 497 ASN A O    1 
ATOM   2199  C  CB   . ASN A 1 290 ? 12.745  -2.326  22.793  1.00 57.89  ? 497 ASN A CB   1 
ATOM   2200  C  CG   . ASN A 1 290 ? 12.343  -1.593  24.052  1.00 55.41  ? 497 ASN A CG   1 
ATOM   2201  O  OD1  . ASN A 1 290 ? 11.861  -0.465  23.977  1.00 49.72  ? 497 ASN A OD1  1 
ATOM   2202  N  ND2  . ASN A 1 290 ? 12.457  -2.255  25.201  1.00 51.37  ? 497 ASN A ND2  1 
ATOM   2203  N  N    . TYR A 1 291 ? 11.416  -3.536  19.663  1.00 57.77  ? 498 TYR A N    1 
ATOM   2204  C  CA   . TYR A 1 291 ? 11.804  -3.932  18.319  1.00 51.00  ? 498 TYR A CA   1 
ATOM   2205  C  C    . TYR A 1 291 ? 11.712  -2.789  17.330  1.00 50.04  ? 498 TYR A C    1 
ATOM   2206  O  O    . TYR A 1 291 ? 12.314  -2.882  16.257  1.00 54.67  ? 498 TYR A O    1 
ATOM   2207  C  CB   . TYR A 1 291 ? 10.928  -5.080  17.846  1.00 53.13  ? 498 TYR A CB   1 
ATOM   2208  C  CG   . TYR A 1 291 ? 11.284  -6.408  18.454  1.00 55.38  ? 498 TYR A CG   1 
ATOM   2209  C  CD1  . TYR A 1 291 ? 12.346  -6.538  19.352  1.00 54.48  ? 498 TYR A CD1  1 
ATOM   2210  C  CD2  . TYR A 1 291 ? 10.569  -7.549  18.114  1.00 56.39  ? 498 TYR A CD2  1 
ATOM   2211  C  CE1  . TYR A 1 291 ? 12.674  -7.801  19.904  1.00 53.87  ? 498 TYR A CE1  1 
ATOM   2212  C  CE2  . TYR A 1 291 ? 10.888  -8.802  18.640  1.00 51.36  ? 498 TYR A CE2  1 
ATOM   2213  C  CZ   . TYR A 1 291 ? 11.926  -8.920  19.532  1.00 54.84  ? 498 TYR A CZ   1 
ATOM   2214  O  OH   . TYR A 1 291 ? 12.201  -10.164 20.038  1.00 56.11  ? 498 TYR A OH   1 
ATOM   2215  N  N    . GLY A 1 292 ? 10.978  -1.717  17.654  1.00 52.67  ? 499 GLY A N    1 
ATOM   2216  C  CA   . GLY A 1 292 ? 10.767  -0.633  16.703  1.00 57.12  ? 499 GLY A CA   1 
ATOM   2217  C  C    . GLY A 1 292 ? 9.712   -0.953  15.651  1.00 52.27  ? 499 GLY A C    1 
ATOM   2218  O  O    . GLY A 1 292 ? 8.957   -1.911  15.761  1.00 53.12  ? 499 GLY A O    1 
ATOM   2219  N  N    . GLY A 1 293 ? 9.674   -0.120  14.607  1.00 65.63  ? 500 GLY A N    1 
ATOM   2220  C  CA   . GLY A 1 293 ? 8.725   -0.267  13.503  1.00 56.77  ? 500 GLY A CA   1 
ATOM   2221  C  C    . GLY A 1 293 ? 7.632   0.786   13.419  1.00 66.51  ? 500 GLY A C    1 
ATOM   2222  O  O    . GLY A 1 293 ? 7.741   1.763   12.669  1.00 71.17  ? 500 GLY A O    1 
ATOM   2223  N  N    . CYS A 1 303 ? 9.645   5.967   16.779  1.00 65.89  ? 510 CYS A N    1 
ATOM   2224  C  CA   . CYS A 1 303 ? 10.090  6.846   17.855  1.00 65.85  ? 510 CYS A CA   1 
ATOM   2225  C  C    . CYS A 1 303 ? 11.032  6.185   18.863  1.00 63.13  ? 510 CYS A C    1 
ATOM   2226  O  O    . CYS A 1 303 ? 12.104  6.716   19.168  1.00 64.29  ? 510 CYS A O    1 
ATOM   2227  C  CB   . CYS A 1 303 ? 8.883   7.382   18.616  1.00 71.72  ? 510 CYS A CB   1 
ATOM   2228  S  SG   . CYS A 1 303 ? 9.293   8.843   19.556  1.00 90.75  ? 510 CYS A SG   1 
ATOM   2229  N  N    . THR A 1 304 ? 10.604  5.039   19.380  1.00 53.76  ? 511 THR A N    1 
ATOM   2230  C  CA   . THR A 1 304 ? 11.199  4.396   20.539  1.00 57.18  ? 511 THR A CA   1 
ATOM   2231  C  C    . THR A 1 304 ? 11.686  3.014   20.154  1.00 63.46  ? 511 THR A C    1 
ATOM   2232  O  O    . THR A 1 304 ? 10.888  2.199   19.671  1.00 63.02  ? 511 THR A O    1 
ATOM   2233  C  CB   . THR A 1 304 ? 10.168  4.266   21.652  1.00 54.97  ? 511 THR A CB   1 
ATOM   2234  O  OG1  . THR A 1 304 ? 9.577   5.543   21.888  1.00 64.43  ? 511 THR A OG1  1 
ATOM   2235  C  CG2  . THR A 1 304 ? 10.795  3.731   22.924  1.00 55.54  ? 511 THR A CG2  1 
ATOM   2236  N  N    . ASN A 1 305 ? 12.971  2.729   20.405  1.00 58.25  ? 512 ASN A N    1 
ATOM   2237  C  CA   . ASN A 1 305 ? 13.512  1.423   20.017  1.00 59.29  ? 512 ASN A CA   1 
ATOM   2238  C  C    . ASN A 1 305 ? 14.896  1.194   20.638  1.00 59.37  ? 512 ASN A C    1 
ATOM   2239  O  O    . ASN A 1 305 ? 15.528  2.104   21.186  1.00 56.54  ? 512 ASN A O    1 
ATOM   2240  C  CB   . ASN A 1 305 ? 13.583  1.320   18.500  1.00 48.30  ? 512 ASN A CB   1 
ATOM   2241  C  CG   . ASN A 1 305 ? 13.983  2.616   17.896  1.00 54.63  ? 512 ASN A CG   1 
ATOM   2242  O  OD1  . ASN A 1 305 ? 15.090  3.083   18.142  1.00 62.49  ? 512 ASN A OD1  1 
ATOM   2243  N  ND2  . ASN A 1 305 ? 13.070  3.259   17.166  1.00 53.34  ? 512 ASN A ND2  1 
ATOM   2244  N  N    . ALA A 1 306 ? 15.357  -0.052  20.535  1.00 54.36  ? 513 ALA A N    1 
ATOM   2245  C  CA   . ALA A 1 306 ? 16.679  -0.410  21.026  1.00 55.05  ? 513 ALA A CA   1 
ATOM   2246  C  C    . ALA A 1 306 ? 17.746  0.258   20.178  1.00 52.11  ? 513 ALA A C    1 
ATOM   2247  O  O    . ALA A 1 306 ? 17.656  0.267   18.945  1.00 53.87  ? 513 ALA A O    1 
ATOM   2248  C  CB   . ALA A 1 306 ? 16.872  -1.927  21.004  1.00 50.72  ? 513 ALA A CB   1 
ATOM   2249  N  N    . TYR A 1 307 ? 18.746  0.828   20.845  1.00 44.77  ? 514 TYR A N    1 
ATOM   2250  C  CA   . TYR A 1 307 ? 19.941  1.379   20.209  1.00 47.84  ? 514 TYR A CA   1 
ATOM   2251  C  C    . TYR A 1 307 ? 21.191  0.595   20.559  1.00 47.80  ? 514 TYR A C    1 
ATOM   2252  O  O    . TYR A 1 307 ? 22.037  0.356   19.693  1.00 48.77  ? 514 TYR A O    1 
ATOM   2253  C  CB   . TYR A 1 307 ? 20.135  2.842   20.628  1.00 49.69  ? 514 TYR A CB   1 
ATOM   2254  C  CG   . TYR A 1 307 ? 21.348  3.506   20.029  1.00 49.96  ? 514 TYR A CG   1 
ATOM   2255  C  CD1  . TYR A 1 307 ? 21.795  3.152   18.767  1.00 47.13  ? 514 TYR A CD1  1 
ATOM   2256  C  CD2  . TYR A 1 307 ? 22.060  4.492   20.733  1.00 44.20  ? 514 TYR A CD2  1 
ATOM   2257  C  CE1  . TYR A 1 307 ? 22.912  3.762   18.205  1.00 44.37  ? 514 TYR A CE1  1 
ATOM   2258  C  CE2  . TYR A 1 307 ? 23.170  5.110   20.176  1.00 42.28  ? 514 TYR A CE2  1 
ATOM   2259  C  CZ   . TYR A 1 307 ? 23.583  4.736   18.906  1.00 43.99  ? 514 TYR A CZ   1 
ATOM   2260  O  OH   . TYR A 1 307 ? 24.672  5.306   18.314  1.00 46.85  ? 514 TYR A OH   1 
ATOM   2261  N  N    . MET A 1 308 ? 21.300  0.228   21.837  1.00 45.18  ? 515 MET A N    1 
ATOM   2262  C  CA   . MET A 1 308 ? 22.435  -0.589  22.320  1.00 44.98  ? 515 MET A CA   1 
ATOM   2263  C  C    . MET A 1 308 ? 21.897  -1.825  23.029  1.00 45.68  ? 515 MET A C    1 
ATOM   2264  O  O    . MET A 1 308 ? 20.950  -1.698  23.798  1.00 50.00  ? 515 MET A O    1 
ATOM   2265  C  CB   . MET A 1 308 ? 23.315  0.180   23.306  1.00 49.49  ? 515 MET A CB   1 
ATOM   2266  C  CG   . MET A 1 308 ? 24.668  0.549   22.746  1.00 54.88  ? 515 MET A CG   1 
ATOM   2267  S  SD   . MET A 1 308 ? 25.774  1.190   24.016  1.00 57.85  ? 515 MET A SD   1 
ATOM   2268  C  CE   . MET A 1 308 ? 26.097  -0.300  24.952  1.00 49.07  ? 515 MET A CE   1 
ATOM   2269  N  N    . LEU A 1 309 ? 22.495  -2.977  22.766  1.00 47.47  ? 516 LEU A N    1 
ATOM   2270  C  CA   . LEU A 1 309 ? 22.093  -4.215  23.454  1.00 42.80  ? 516 LEU A CA   1 
ATOM   2271  C  C    . LEU A 1 309 ? 23.290  -4.722  24.247  1.00 48.40  ? 516 LEU A C    1 
ATOM   2272  O  O    . LEU A 1 309 ? 24.408  -4.640  23.739  1.00 50.81  ? 516 LEU A O    1 
ATOM   2273  C  CB   . LEU A 1 309 ? 21.652  -5.232  22.406  1.00 42.32  ? 516 LEU A CB   1 
ATOM   2274  C  CG   . LEU A 1 309 ? 20.386  -4.885  21.636  1.00 49.01  ? 516 LEU A CG   1 
ATOM   2275  C  CD1  . LEU A 1 309 ? 20.151  -5.900  20.537  1.00 44.11  ? 516 LEU A CD1  1 
ATOM   2276  C  CD2  . LEU A 1 309 ? 19.198  -4.826  22.574  1.00 45.85  ? 516 LEU A CD2  1 
ATOM   2277  N  N    . VAL A 1 310 ? 23.053  -5.195  25.465  1.00 44.93  ? 517 VAL A N    1 
ATOM   2278  C  CA   . VAL A 1 310 ? 24.152  -5.806  26.256  1.00 43.76  ? 517 VAL A CA   1 
ATOM   2279  C  C    . VAL A 1 310 ? 23.834  -7.285  26.442  1.00 48.94  ? 517 VAL A C    1 
ATOM   2280  O  O    . VAL A 1 310 ? 22.778  -7.586  27.002  1.00 52.77  ? 517 VAL A O    1 
ATOM   2281  C  CB   . VAL A 1 310 ? 24.408  -5.092  27.597  1.00 43.51  ? 517 VAL A CB   1 
ATOM   2282  C  CG1  . VAL A 1 310 ? 25.420  -5.829  28.456  1.00 34.87  ? 517 VAL A CG1  1 
ATOM   2283  C  CG2  . VAL A 1 310 ? 24.830  -3.651  27.391  1.00 41.66  ? 517 VAL A CG2  1 
ATOM   2284  N  N    . TYR A 1 311 ? 24.694  -8.157  25.922  1.00 44.91  ? 518 TYR A N    1 
ATOM   2285  C  CA   . TYR A 1 311 ? 24.540  -9.610  26.135  1.00 45.33  ? 518 TYR A CA   1 
ATOM   2286  C  C    . TYR A 1 311 ? 25.725  -10.087 26.959  1.00 48.32  ? 518 TYR A C    1 
ATOM   2287  O  O    . TYR A 1 311 ? 26.816  -9.562  26.813  1.00 51.16  ? 518 TYR A O    1 
ATOM   2288  C  CB   . TYR A 1 311 ? 24.503  -10.388 24.820  1.00 49.50  ? 518 TYR A CB   1 
ATOM   2289  C  CG   . TYR A 1 311 ? 23.252  -10.260 23.995  1.00 46.78  ? 518 TYR A CG   1 
ATOM   2290  C  CD1  . TYR A 1 311 ? 23.020  -9.133  23.229  1.00 45.96  ? 518 TYR A CD1  1 
ATOM   2291  C  CD2  . TYR A 1 311 ? 22.320  -11.280 23.950  1.00 50.27  ? 518 TYR A CD2  1 
ATOM   2292  C  CE1  . TYR A 1 311 ? 21.880  -9.009  22.460  1.00 48.04  ? 518 TYR A CE1  1 
ATOM   2293  C  CE2  . TYR A 1 311 ? 21.171  -11.172 23.187  1.00 47.61  ? 518 TYR A CE2  1 
ATOM   2294  C  CZ   . TYR A 1 311 ? 20.955  -10.032 22.436  1.00 53.86  ? 518 TYR A CZ   1 
ATOM   2295  O  OH   . TYR A 1 311 ? 19.831  -9.894  21.685  1.00 56.57  ? 518 TYR A OH   1 
ATOM   2296  N  N    . ILE A 1 312 ? 25.495  -11.043 27.837  1.00 49.54  ? 519 ILE A N    1 
ATOM   2297  C  CA   . ILE A 1 312 ? 26.553  -11.624 28.643  1.00 47.89  ? 519 ILE A CA   1 
ATOM   2298  C  C    . ILE A 1 312 ? 26.668  -13.093 28.270  1.00 46.89  ? 519 ILE A C    1 
ATOM   2299  O  O    . ILE A 1 312 ? 25.654  -13.773 28.093  1.00 50.37  ? 519 ILE A O    1 
ATOM   2300  C  CB   . ILE A 1 312 ? 26.252  -11.445 30.145  1.00 48.97  ? 519 ILE A CB   1 
ATOM   2301  C  CG1  . ILE A 1 312 ? 26.214  -9.964  30.483  1.00 43.49  ? 519 ILE A CG1  1 
ATOM   2302  C  CG2  . ILE A 1 312 ? 27.276  -12.160 30.998  1.00 45.69  ? 519 ILE A CG2  1 
ATOM   2303  C  CD1  . ILE A 1 312 ? 25.564  -9.679  31.828  1.00 53.85  ? 519 ILE A CD1  1 
ATOM   2304  N  N    . ARG A 1 313 ? 27.898  -13.579 28.135  1.00 47.22  ? 520 ARG A N    1 
ATOM   2305  C  CA   . ARG A 1 313 ? 28.115  -14.966 27.745  1.00 47.80  ? 520 ARG A CA   1 
ATOM   2306  C  C    . ARG A 1 313 ? 27.616  -15.891 28.848  1.00 52.94  ? 520 ARG A C    1 
ATOM   2307  O  O    . ARG A 1 313 ? 27.996  -15.733 30.019  1.00 50.27  ? 520 ARG A O    1 
ATOM   2308  C  CB   . ARG A 1 313 ? 29.601  -15.215 27.468  1.00 44.80  ? 520 ARG A CB   1 
ATOM   2309  C  CG   . ARG A 1 313 ? 29.884  -16.439 26.627  1.00 45.22  ? 520 ARG A CG   1 
ATOM   2310  C  CD   . ARG A 1 313 ? 31.366  -16.665 26.566  1.00 51.58  ? 520 ARG A CD   1 
ATOM   2311  N  NE   . ARG A 1 313 ? 31.776  -17.763 25.695  1.00 56.92  ? 520 ARG A NE   1 
ATOM   2312  C  CZ   . ARG A 1 313 ? 32.405  -17.611 24.532  1.00 49.14  ? 520 ARG A CZ   1 
ATOM   2313  N  NH1  . ARG A 1 313 ? 32.668  -16.404 24.062  1.00 43.64  ? 520 ARG A NH1  1 
ATOM   2314  N  NH2  . ARG A 1 313 ? 32.752  -18.675 23.828  1.00 51.76  ? 520 ARG A NH2  1 
ATOM   2315  N  N    . GLU A 1 314 ? 26.753  -16.844 28.498  1.00 48.34  ? 521 GLU A N    1 
ATOM   2316  C  CA   . GLU A 1 314 ? 26.133  -17.755 29.494  1.00 49.61  ? 521 GLU A CA   1 
ATOM   2317  C  C    . GLU A 1 314 ? 27.185  -18.400 30.395  1.00 54.19  ? 521 GLU A C    1 
ATOM   2318  O  O    . GLU A 1 314 ? 26.964  -18.450 31.610  1.00 56.11  ? 521 GLU A O    1 
ATOM   2319  C  CB   . GLU A 1 314 ? 25.340  -18.824 28.749  1.00 59.53  ? 521 GLU A CB   1 
ATOM   2320  C  CG   . GLU A 1 314 ? 24.337  -19.583 29.594  1.00 58.39  ? 521 GLU A CG   1 
ATOM   2321  C  CD   . GLU A 1 314 ? 23.390  -20.455 28.787  1.00 69.66  ? 521 GLU A CD   1 
ATOM   2322  O  OE1  . GLU A 1 314 ? 23.852  -21.111 27.836  1.00 67.98  ? 521 GLU A OE1  1 
ATOM   2323  O  OE2  . GLU A 1 314 ? 22.190  -20.475 29.111  1.00 74.56  ? 521 GLU A OE2  1 
ATOM   2324  N  N    . SER A 1 315 ? 28.291  -18.853 29.821  1.00 53.05  ? 522 SER A N    1 
ATOM   2325  C  CA   . SER A 1 315 ? 29.357  -19.525 30.600  1.00 51.47  ? 522 SER A CA   1 
ATOM   2326  C  C    . SER A 1 315 ? 29.931  -18.611 31.681  1.00 53.34  ? 522 SER A C    1 
ATOM   2327  O  O    . SER A 1 315 ? 30.562  -19.136 32.599  1.00 56.68  ? 522 SER A O    1 
ATOM   2328  C  CB   . SER A 1 315 ? 30.434  -19.979 29.678  1.00 49.45  ? 522 SER A CB   1 
ATOM   2329  O  OG   . SER A 1 315 ? 31.101  -18.875 29.096  1.00 64.11  ? 522 SER A OG   1 
ATOM   2330  N  N    . LYS A 1 316 ? 29.742  -17.303 31.558  1.00 52.77  ? 523 LYS A N    1 
ATOM   2331  C  CA   . LYS A 1 316 ? 30.343  -16.342 32.507  1.00 54.20  ? 523 LYS A CA   1 
ATOM   2332  C  C    . LYS A 1 316 ? 29.257  -15.554 33.238  1.00 52.68  ? 523 LYS A C    1 
ATOM   2333  O  O    . LYS A 1 316 ? 29.622  -14.634 33.954  1.00 53.30  ? 523 LYS A O    1 
ATOM   2334  C  CB   . LYS A 1 316 ? 31.250  -15.374 31.745  1.00 52.67  ? 523 LYS A CB   1 
ATOM   2335  C  CG   . LYS A 1 316 ? 32.167  -15.991 30.703  1.00 56.23  ? 523 LYS A CG   1 
ATOM   2336  C  CD   . LYS A 1 316 ? 33.461  -16.486 31.293  1.00 57.39  ? 523 LYS A CD   1 
ATOM   2337  C  CE   . LYS A 1 316 ? 34.404  -17.042 30.252  1.00 48.08  ? 523 LYS A CE   1 
ATOM   2338  N  NZ   . LYS A 1 316 ? 35.717  -17.383 30.845  1.00 66.61  ? 523 LYS A NZ   1 
ATOM   2339  N  N    . LEU A 1 317 ? 27.984  -15.911 33.099  1.00 53.85  ? 524 LEU A N    1 
ATOM   2340  C  CA   . LEU A 1 317 ? 26.937  -15.176 33.852  1.00 54.81  ? 524 LEU A CA   1 
ATOM   2341  C  C    . LEU A 1 317 ? 27.196  -15.222 35.361  1.00 57.19  ? 524 LEU A C    1 
ATOM   2342  O  O    . LEU A 1 317 ? 27.104  -14.173 35.990  1.00 61.74  ? 524 LEU A O    1 
ATOM   2343  C  CB   . LEU A 1 317 ? 25.553  -15.735 33.518  1.00 53.80  ? 524 LEU A CB   1 
ATOM   2344  C  CG   . LEU A 1 317 ? 24.410  -14.745 33.726  1.00 60.23  ? 524 LEU A CG   1 
ATOM   2345  C  CD1  . LEU A 1 317 ? 23.981  -14.120 32.411  1.00 58.71  ? 524 LEU A CD1  1 
ATOM   2346  C  CD2  . LEU A 1 317 ? 23.233  -15.409 34.415  1.00 49.50  ? 524 LEU A CD2  1 
ATOM   2347  N  N    . SER A 1 318 ? 27.478  -16.400 35.911  1.00 56.24  ? 525 SER A N    1 
ATOM   2348  C  CA   . SER A 1 318 ? 27.723  -16.534 37.368  1.00 55.63  ? 525 SER A CA   1 
ATOM   2349  C  C    . SER A 1 318 ? 28.811  -15.572 37.825  1.00 58.54  ? 525 SER A C    1 
ATOM   2350  O  O    . SER A 1 318 ? 28.622  -14.927 38.854  1.00 60.96  ? 525 SER A O    1 
ATOM   2351  C  CB   . SER A 1 318 ? 28.083  -17.949 37.710  1.00 50.38  ? 525 SER A CB   1 
ATOM   2352  O  OG   . SER A 1 318 ? 29.306  -18.336 37.104  1.00 60.18  ? 525 SER A OG   1 
ATOM   2353  N  N    . GLU A 1 319 ? 29.918  -15.515 37.092  1.00 62.87  ? 526 GLU A N    1 
ATOM   2354  C  CA   . GLU A 1 319 ? 31.029  -14.669 37.535  1.00 62.22  ? 526 GLU A CA   1 
ATOM   2355  C  C    . GLU A 1 319 ? 30.733  -13.194 37.298  1.00 56.38  ? 526 GLU A C    1 
ATOM   2356  O  O    . GLU A 1 319 ? 30.917  -12.365 38.192  1.00 65.02  ? 526 GLU A O    1 
ATOM   2357  C  CB   . GLU A 1 319 ? 32.328  -15.062 36.827  1.00 55.82  ? 526 GLU A CB   1 
ATOM   2358  C  CG   . GLU A 1 319 ? 33.540  -14.324 37.338  1.00 58.88  ? 526 GLU A CG   1 
ATOM   2359  C  CD   . GLU A 1 319 ? 34.791  -14.623 36.528  1.00 71.13  ? 526 GLU A CD   1 
ATOM   2360  O  OE1  . GLU A 1 319 ? 35.709  -13.769 36.524  1.00 71.17  ? 526 GLU A OE1  1 
ATOM   2361  O  OE2  . GLU A 1 319 ? 34.857  -15.702 35.891  1.00 67.50  ? 526 GLU A OE2  1 
ATOM   2362  N  N    . VAL A 1 320 ? 30.294  -12.845 36.096  1.00 55.13  ? 527 VAL A N    1 
ATOM   2363  C  CA   . VAL A 1 320 ? 30.090  -11.410 35.755  1.00 53.02  ? 527 VAL A CA   1 
ATOM   2364  C  C    . VAL A 1 320 ? 29.003  -10.819 36.655  1.00 57.89  ? 527 VAL A C    1 
ATOM   2365  O  O    . VAL A 1 320 ? 29.182  -9.683  37.091  1.00 52.43  ? 527 VAL A O    1 
ATOM   2366  C  CB   . VAL A 1 320 ? 29.781  -11.253 34.256  1.00 48.14  ? 527 VAL A CB   1 
ATOM   2367  C  CG1  . VAL A 1 320 ? 29.264  -9.871  33.894  1.00 45.75  ? 527 VAL A CG1  1 
ATOM   2368  C  CG2  . VAL A 1 320 ? 30.984  -11.607 33.402  1.00 51.77  ? 527 VAL A CG2  1 
ATOM   2369  N  N    . LEU A 1 321 ? 27.941  -11.573 36.940  1.00 55.11  ? 528 LEU A N    1 
ATOM   2370  C  CA   . LEU A 1 321 ? 26.801  -11.034 37.730  1.00 56.40  ? 528 LEU A CA   1 
ATOM   2371  C  C    . LEU A 1 321 ? 26.845  -11.585 39.157  1.00 58.14  ? 528 LEU A C    1 
ATOM   2372  O  O    . LEU A 1 321 ? 25.779  -11.701 39.769  1.00 55.09  ? 528 LEU A O    1 
ATOM   2373  C  CB   . LEU A 1 321 ? 25.495  -11.373 37.009  1.00 49.50  ? 528 LEU A CB   1 
ATOM   2374  C  CG   . LEU A 1 321 ? 25.328  -10.754 35.625  1.00 52.64  ? 528 LEU A CG   1 
ATOM   2375  C  CD1  . LEU A 1 321 ? 23.919  -10.970 35.114  1.00 56.51  ? 528 LEU A CD1  1 
ATOM   2376  C  CD2  . LEU A 1 321 ? 25.648  -9.273  35.654  1.00 51.67  ? 528 LEU A CD2  1 
ATOM   2377  N  N    . GLN A 1 322 ? 28.042  -11.879 39.664  1.00 58.51  ? 529 GLN A N    1 
ATOM   2378  C  CA   . GLN A 1 322 ? 28.217  -12.343 41.061  1.00 56.49  ? 529 GLN A CA   1 
ATOM   2379  C  C    . GLN A 1 322 ? 27.676  -11.283 42.011  1.00 64.38  ? 529 GLN A C    1 
ATOM   2380  O  O    . GLN A 1 322 ? 27.970  -10.103 41.807  1.00 56.93  ? 529 GLN A O    1 
ATOM   2381  C  CB   . GLN A 1 322 ? 29.693  -12.606 41.345  1.00 63.84  ? 529 GLN A CB   1 
ATOM   2382  C  CG   . GLN A 1 322 ? 30.026  -12.821 42.813  1.00 71.10  ? 529 GLN A CG   1 
ATOM   2383  C  CD   . GLN A 1 322 ? 31.314  -13.579 43.009  1.00 74.95  ? 529 GLN A CD   1 
ATOM   2384  O  OE1  . GLN A 1 322 ? 32.394  -13.106 42.666  1.00 81.04  ? 529 GLN A OE1  1 
ATOM   2385  N  NE2  . GLN A 1 322 ? 31.207  -14.771 43.571  1.00 69.05  ? 529 GLN A NE2  1 
ATOM   2386  N  N    . ALA A 1 323 ? 26.973  -11.711 43.050  1.00 63.82  ? 530 ALA A N    1 
ATOM   2387  C  CA   . ALA A 1 323 ? 26.341  -10.783 43.970  1.00 59.77  ? 530 ALA A CA   1 
ATOM   2388  C  C    . ALA A 1 323 ? 27.406  -9.945  44.668  1.00 65.23  ? 530 ALA A C    1 
ATOM   2389  O  O    . ALA A 1 323 ? 28.454  -10.457 45.082  1.00 66.30  ? 530 ALA A O    1 
ATOM   2390  C  CB   . ALA A 1 323 ? 25.486  -11.546 44.978  1.00 58.53  ? 530 ALA A CB   1 
ATOM   2391  N  N    . VAL A 1 324 ? 27.148  -8.642  44.763  1.00 59.08  ? 531 VAL A N    1 
ATOM   2392  C  CA   . VAL A 1 324 ? 28.070  -7.697  45.377  1.00 66.01  ? 531 VAL A CA   1 
ATOM   2393  C  C    . VAL A 1 324 ? 27.496  -7.232  46.706  1.00 70.24  ? 531 VAL A C    1 
ATOM   2394  O  O    . VAL A 1 324 ? 26.331  -6.821  46.781  1.00 70.37  ? 531 VAL A O    1 
ATOM   2395  C  CB   . VAL A 1 324 ? 28.341  -6.481  44.474  1.00 65.96  ? 531 VAL A CB   1 
ATOM   2396  C  CG1  . VAL A 1 324 ? 29.449  -5.605  45.091  1.00 59.25  ? 531 VAL A CG1  1 
ATOM   2397  C  CG2  . VAL A 1 324 ? 28.684  -6.929  43.050  1.00 62.12  ? 531 VAL A CG2  1 
ATOM   2398  N  N    . THR A 1 325 ? 28.327  -7.262  47.746  1.00 66.41  ? 532 THR A N    1 
ATOM   2399  C  CA   . THR A 1 325 ? 27.892  -6.777  49.049  1.00 71.15  ? 532 THR A CA   1 
ATOM   2400  C  C    . THR A 1 325 ? 28.863  -5.758  49.623  1.00 71.46  ? 532 THR A C    1 
ATOM   2401  O  O    . THR A 1 325 ? 29.751  -5.260  48.921  1.00 71.36  ? 532 THR A O    1 
ATOM   2402  C  CB   . THR A 1 325 ? 27.759  -7.927  50.024  1.00 67.73  ? 532 THR A CB   1 
ATOM   2403  O  OG1  . THR A 1 325 ? 28.896  -8.787  49.853  1.00 69.30  ? 532 THR A OG1  1 
ATOM   2404  C  CG2  . THR A 1 325 ? 26.454  -8.682  49.750  1.00 68.00  ? 532 THR A CG2  1 
ATOM   2405  N  N    . ASP A 1 326 ? 28.711  -5.458  50.912  1.00 64.98  ? 533 ASP A N    1 
ATOM   2406  C  CA   . ASP A 1 326 ? 29.572  -4.471  51.527  1.00 55.19  ? 533 ASP A CA   1 
ATOM   2407  C  C    . ASP A 1 326 ? 30.978  -5.008  51.766  1.00 63.55  ? 533 ASP A C    1 
ATOM   2408  O  O    . ASP A 1 326 ? 31.896  -4.213  51.985  1.00 67.27  ? 533 ASP A O    1 
ATOM   2409  C  CB   . ASP A 1 326 ? 28.934  -3.972  52.824  1.00 61.07  ? 533 ASP A CB   1 
ATOM   2410  C  CG   . ASP A 1 326 ? 27.871  -2.901  52.579  1.00 71.56  ? 533 ASP A CG   1 
ATOM   2411  O  OD1  . ASP A 1 326 ? 27.307  -2.889  51.470  1.00 71.33  ? 533 ASP A OD1  1 
ATOM   2412  O  OD2  . ASP A 1 326 ? 27.604  -2.065  53.478  1.00 79.27  ? 533 ASP A OD2  1 
ATOM   2413  N  N    . HIS A 1 327 ? 31.180  -6.326  51.716  1.00 58.33  ? 534 HIS A N    1 
ATOM   2414  C  CA   . HIS A 1 327 ? 32.541  -6.842  51.796  1.00 64.62  ? 534 HIS A CA   1 
ATOM   2415  C  C    . HIS A 1 327 ? 33.360  -6.568  50.526  1.00 70.80  ? 534 HIS A C    1 
ATOM   2416  O  O    . HIS A 1 327 ? 34.590  -6.719  50.558  1.00 66.09  ? 534 HIS A O    1 
ATOM   2417  C  CB   . HIS A 1 327 ? 32.532  -8.350  52.105  1.00 69.33  ? 534 HIS A CB   1 
ATOM   2418  C  CG   . HIS A 1 327 ? 31.694  -8.724  53.293  1.00 65.74  ? 534 HIS A CG   1 
ATOM   2419  N  ND1  . HIS A 1 327 ? 30.618  -9.582  53.203  1.00 69.59  ? 534 HIS A ND1  1 
ATOM   2420  C  CD2  . HIS A 1 327 ? 31.757  -8.333  54.589  1.00 61.66  ? 534 HIS A CD2  1 
ATOM   2421  C  CE1  . HIS A 1 327 ? 30.055  -9.706  54.392  1.00 64.68  ? 534 HIS A CE1  1 
ATOM   2422  N  NE2  . HIS A 1 327 ? 30.725  -8.956  55.249  1.00 63.56  ? 534 HIS A NE2  1 
ATOM   2423  N  N    . ASP A 1 328 ? 32.720  -6.161  49.419  1.00 66.07  ? 535 ASP A N    1 
ATOM   2424  C  CA   . ASP A 1 328 ? 33.428  -5.783  48.195  1.00 62.36  ? 535 ASP A CA   1 
ATOM   2425  C  C    . ASP A 1 328 ? 33.810  -4.301  48.135  1.00 64.93  ? 535 ASP A C    1 
ATOM   2426  O  O    . ASP A 1 328 ? 34.541  -3.910  47.228  1.00 65.67  ? 535 ASP A O    1 
ATOM   2427  C  CB   . ASP A 1 328 ? 32.586  -6.115  46.953  1.00 62.65  ? 535 ASP A CB   1 
ATOM   2428  C  CG   . ASP A 1 328 ? 32.117  -7.567  46.915  1.00 70.82  ? 535 ASP A CG   1 
ATOM   2429  O  OD1  . ASP A 1 328 ? 32.969  -8.500  46.995  1.00 64.11  ? 535 ASP A OD1  1 
ATOM   2430  O  OD2  . ASP A 1 328 ? 30.876  -7.765  46.795  1.00 67.89  ? 535 ASP A OD2  1 
ATOM   2431  N  N    . ILE A 1 329 ? 33.298  -3.495  49.058  1.00 64.18  ? 536 ILE A N    1 
ATOM   2432  C  CA   . ILE A 1 329 ? 33.670  -2.056  49.118  1.00 61.36  ? 536 ILE A CA   1 
ATOM   2433  C  C    . ILE A 1 329 ? 34.745  -1.892  50.189  1.00 69.77  ? 536 ILE A C    1 
ATOM   2434  O  O    . ILE A 1 329 ? 34.434  -2.111  51.367  1.00 71.25  ? 536 ILE A O    1 
ATOM   2435  C  CB   . ILE A 1 329 ? 32.445  -1.178  49.413  1.00 60.51  ? 536 ILE A CB   1 
ATOM   2436  C  CG1  . ILE A 1 329 ? 31.164  -1.795  48.847  1.00 63.36  ? 536 ILE A CG1  1 
ATOM   2437  C  CG2  . ILE A 1 329 ? 32.671  0.237   48.908  1.00 64.44  ? 536 ILE A CG2  1 
ATOM   2438  C  CD1  . ILE A 1 329 ? 30.103  -0.798  48.497  1.00 62.27  ? 536 ILE A CD1  1 
ATOM   2439  N  N    . PRO A 1 330 ? 35.995  -1.542  49.826  1.00 73.57  ? 537 PRO A N    1 
ATOM   2440  C  CA   . PRO A 1 330 ? 37.048  -1.286  50.811  1.00 74.01  ? 537 PRO A CA   1 
ATOM   2441  C  C    . PRO A 1 330 ? 36.648  -0.263  51.884  1.00 71.99  ? 537 PRO A C    1 
ATOM   2442  O  O    . PRO A 1 330 ? 36.032  0.718   51.543  1.00 68.28  ? 537 PRO A O    1 
ATOM   2443  C  CB   . PRO A 1 330 ? 38.168  -0.735  49.929  1.00 71.88  ? 537 PRO A CB   1 
ATOM   2444  C  CG   . PRO A 1 330 ? 37.970  -1.448  48.625  1.00 65.81  ? 537 PRO A CG   1 
ATOM   2445  C  CD   . PRO A 1 330 ? 36.471  -1.413  48.452  1.00 66.23  ? 537 PRO A CD   1 
ATOM   2446  N  N    . GLN A 1 331 ? 37.039  -0.499  53.138  1.00 76.52  ? 538 GLN A N    1 
ATOM   2447  C  CA   . GLN A 1 331 ? 36.628  0.385   54.264  1.00 72.50  ? 538 GLN A CA   1 
ATOM   2448  C  C    . GLN A 1 331 ? 37.204  1.786   54.080  1.00 76.22  ? 538 GLN A C    1 
ATOM   2449  O  O    . GLN A 1 331 ? 36.534  2.744   54.467  1.00 71.30  ? 538 GLN A O    1 
ATOM   2450  N  N    . GLN A 1 332 ? 38.409  1.878   53.533  1.00 80.18  ? 539 GLN A N    1 
ATOM   2451  C  CA   . GLN A 1 332 ? 39.069  3.184   53.319  1.00 74.89  ? 539 GLN A CA   1 
ATOM   2452  C  C    . GLN A 1 332 ? 38.149  4.052   52.467  1.00 77.18  ? 539 GLN A C    1 
ATOM   2453  O  O    . GLN A 1 332 ? 38.014  5.241   52.780  1.00 74.18  ? 539 GLN A O    1 
ATOM   2454  C  CB   . GLN A 1 332 ? 40.411  2.955   52.626  1.00 80.37  ? 539 GLN A CB   1 
ATOM   2455  C  CG   . GLN A 1 332 ? 41.211  1.788   53.185  1.00 83.15  ? 539 GLN A CG   1 
ATOM   2456  C  CD   . GLN A 1 332 ? 41.058  0.534   52.360  1.00 89.19  ? 539 GLN A CD   1 
ATOM   2457  O  OE1  . GLN A 1 332 ? 40.457  -0.446  52.794  1.00 90.67  ? 539 GLN A OE1  1 
ATOM   2458  N  NE2  . GLN A 1 332 ? 41.599  0.558   51.153  1.00 83.11  ? 539 GLN A NE2  1 
ATOM   2459  N  N    . LEU A 1 333 ? 37.552  3.467   51.430  1.00 77.62  ? 540 LEU A N    1 
ATOM   2460  C  CA   . LEU A 1 333 ? 36.628  4.208   50.536  1.00 75.35  ? 540 LEU A CA   1 
ATOM   2461  C  C    . LEU A 1 333 ? 35.358  4.551   51.307  1.00 72.80  ? 540 LEU A C    1 
ATOM   2462  O  O    . LEU A 1 333 ? 34.873  5.664   51.151  1.00 70.03  ? 540 LEU A O    1 
ATOM   2463  C  CB   . LEU A 1 333 ? 36.314  3.322   49.329  1.00 72.91  ? 540 LEU A CB   1 
ATOM   2464  C  CG   . LEU A 1 333 ? 35.380  3.920   48.284  1.00 70.54  ? 540 LEU A CG   1 
ATOM   2465  C  CD1  . LEU A 1 333 ? 35.992  5.172   47.684  1.00 65.43  ? 540 LEU A CD1  1 
ATOM   2466  C  CD2  . LEU A 1 333 ? 35.075  2.898   47.205  1.00 68.84  ? 540 LEU A CD2  1 
ATOM   2467  N  N    . VAL A 1 334 ? 34.845  3.601   52.084  1.00 69.93  ? 541 VAL A N    1 
ATOM   2468  C  CA   . VAL A 1 334 ? 33.606  3.842   52.869  1.00 71.68  ? 541 VAL A CA   1 
ATOM   2469  C  C    . VAL A 1 334 ? 33.875  5.039   53.775  1.00 71.07  ? 541 VAL A C    1 
ATOM   2470  O  O    . VAL A 1 334 ? 33.006  5.914   53.854  1.00 70.74  ? 541 VAL A O    1 
ATOM   2471  C  CB   . VAL A 1 334 ? 33.170  2.590   53.652  1.00 77.84  ? 541 VAL A CB   1 
ATOM   2472  C  CG1  . VAL A 1 334 ? 31.919  2.843   54.477  1.00 68.52  ? 541 VAL A CG1  1 
ATOM   2473  C  CG2  . VAL A 1 334 ? 32.957  1.402   52.731  1.00 74.16  ? 541 VAL A CG2  1 
ATOM   2474  N  N    . GLU A 1 335 ? 35.064  5.103   54.377  1.00 75.21  ? 542 GLU A N    1 
ATOM   2475  C  CA   . GLU A 1 335 ? 35.384  6.274   55.184  1.00 77.91  ? 542 GLU A CA   1 
ATOM   2476  C  C    . GLU A 1 335 ? 35.473  7.521   54.313  1.00 74.11  ? 542 GLU A C    1 
ATOM   2477  O  O    . GLU A 1 335 ? 34.870  8.554   54.628  1.00 76.50  ? 542 GLU A O    1 
ATOM   2478  C  CB   . GLU A 1 335 ? 36.684  6.039   55.962  1.00 67.12  ? 542 GLU A CB   1 
ATOM   2479  N  N    . ARG A 1 336 ? 36.201  7.435   53.197  1.00 71.47  ? 543 ARG A N    1 
ATOM   2480  C  CA   . ARG A 1 336 ? 36.343  8.594   52.325  1.00 73.71  ? 543 ARG A CA   1 
ATOM   2481  C  C    . ARG A 1 336 ? 34.980  9.110   51.874  1.00 78.11  ? 543 ARG A C    1 
ATOM   2482  O  O    . ARG A 1 336 ? 34.720  10.319  51.917  1.00 77.95  ? 543 ARG A O    1 
ATOM   2483  C  CB   . ARG A 1 336 ? 37.230  8.242   51.125  1.00 64.89  ? 543 ARG A CB   1 
ATOM   2484  N  N    . LEU A 1 337 ? 34.078  8.205   51.481  1.00 79.23  ? 544 LEU A N    1 
ATOM   2485  C  CA   . LEU A 1 337 ? 32.801  8.632   50.911  1.00 79.99  ? 544 LEU A CA   1 
ATOM   2486  C  C    . LEU A 1 337 ? 31.892  9.245   51.976  1.00 78.70  ? 544 LEU A C    1 
ATOM   2487  O  O    . LEU A 1 337 ? 31.305  10.312  51.757  1.00 82.64  ? 544 LEU A O    1 
ATOM   2488  C  CB   . LEU A 1 337 ? 32.119  7.453   50.206  1.00 73.52  ? 544 LEU A CB   1 
ATOM   2489  N  N    . GLN A 1 338 ? 31.773  8.595   53.142  1.00 78.99  ? 545 GLN A N    1 
ATOM   2490  C  CA   . GLN A 1 338 ? 30.918  9.128   54.207  1.00 82.42  ? 545 GLN A CA   1 
ATOM   2491  C  C    . GLN A 1 338 ? 31.530  10.377  54.832  1.00 83.86  ? 545 GLN A C    1 
ATOM   2492  O  O    . GLN A 1 338 ? 30.835  11.379  55.051  1.00 84.23  ? 545 GLN A O    1 
ATOM   2493  C  CB   . GLN A 1 338 ? 30.666  8.059   55.276  1.00 76.46  ? 545 GLN A CB   1 
ATOM   2494  N  N    . GLU A 1 339 ? 32.834  10.342  55.107  1.00 84.95  ? 546 GLU A N    1 
ATOM   2495  C  CA   . GLU A 1 339 ? 33.549  11.492  55.661  1.00 87.41  ? 546 GLU A CA   1 
ATOM   2496  C  C    . GLU A 1 339 ? 33.840  12.520  54.565  1.00 88.05  ? 546 GLU A C    1 
ATOM   2497  O  O    . GLU A 1 339 ? 34.981  12.903  54.311  1.00 88.67  ? 546 GLU A O    1 
ATOM   2498  N  N    . GLU A 1 340 ? 32.752  12.967  53.914  1.00 86.23  ? 547 GLU A N    1 
ATOM   2499  C  CA   . GLU A 1 340 ? 32.777  13.875  52.763  1.00 87.98  ? 547 GLU A CA   1 
ATOM   2500  C  C    . GLU A 1 340 ? 31.461  14.659  52.780  1.00 87.81  ? 547 GLU A C    1 
ATOM   2501  O  O    . GLU A 1 340 ? 30.511  14.349  52.057  1.00 85.44  ? 547 GLU A O    1 
ATOM   2502  C  CB   . GLU A 1 340 ? 32.956  13.132  51.440  1.00 81.57  ? 547 GLU A CB   1 
ATOM   2503  N  N    . LYS A 1 341 ? 31.413  15.684  53.629  1.00 90.42  ? 548 LYS A N    1 
ATOM   2504  C  CA   . LYS A 1 341 ? 30.195  16.464  53.846  1.00 89.95  ? 548 LYS A CA   1 
ATOM   2505  C  C    . LYS A 1 341 ? 30.477  17.965  53.915  1.00 83.31  ? 548 LYS A C    1 
ATOM   2506  O  O    . LYS A 1 341 ? 29.632  18.782  53.549  1.00 78.99  ? 548 LYS A O    1 
ATOM   2507  C  CB   . LYS A 1 341 ? 29.509  15.998  55.128  1.00 82.82  ? 548 LYS A CB   1 
ATOM   2508  C  CG   . LYS A 1 341 ? 29.065  14.556  55.078  1.00 80.52  ? 548 LYS A CG   1 
ATOM   2509  C  CD   . LYS A 1 341 ? 28.071  14.360  53.946  1.00 85.06  ? 548 LYS A CD   1 
ATOM   2510  C  CE   . LYS A 1 341 ? 27.922  12.896  53.586  1.00 83.42  ? 548 LYS A CE   1 
ATOM   2511  N  NZ   . LYS A 1 341 ? 29.183  12.372  53.025  1.00 83.00  ? 548 LYS A NZ   1 
ATOM   2512  N  N    . MET B 2 1   ? 48.921  5.128   2.478   1.00 53.89  ? 1   MET B N    1 
ATOM   2513  C  CA   . MET B 2 1   ? 48.580  3.749   2.833   1.00 56.96  ? 1   MET B CA   1 
ATOM   2514  C  C    . MET B 2 1   ? 47.084  3.553   2.710   1.00 51.10  ? 1   MET B C    1 
ATOM   2515  O  O    . MET B 2 1   ? 46.310  4.502   2.825   1.00 56.42  ? 1   MET B O    1 
ATOM   2516  C  CB   . MET B 2 1   ? 49.048  3.391   4.264   1.00 51.66  ? 1   MET B CB   1 
ATOM   2517  C  CG   . MET B 2 1   ? 48.535  4.306   5.378   1.00 53.68  ? 1   MET B CG   1 
ATOM   2518  S  SD   . MET B 2 1   ? 49.008  3.755   7.043   1.00 63.60  ? 1   MET B SD   1 
ATOM   2519  C  CE   . MET B 2 1   ? 48.231  5.041   7.994   1.00 56.57  ? 1   MET B CE   1 
ATOM   2520  N  N    . GLN B 2 2   ? 46.661  2.328   2.472   1.00 51.68  ? 2   GLN B N    1 
ATOM   2521  C  CA   . GLN B 2 2   ? 45.249  2.040   2.289   1.00 52.36  ? 2   GLN B CA   1 
ATOM   2522  C  C    . GLN B 2 2   ? 44.711  1.402   3.567   1.00 53.21  ? 2   GLN B C    1 
ATOM   2523  O  O    . GLN B 2 2   ? 45.128  0.292   3.925   1.00 50.44  ? 2   GLN B O    1 
ATOM   2524  C  CB   . GLN B 2 2   ? 45.036  1.125   1.081   1.00 46.74  ? 2   GLN B CB   1 
ATOM   2525  C  CG   . GLN B 2 2   ? 43.581  0.927   0.707   1.00 46.92  ? 2   GLN B CG   1 
ATOM   2526  C  CD   . GLN B 2 2   ? 43.390  -0.097  -0.397  1.00 52.15  ? 2   GLN B CD   1 
ATOM   2527  O  OE1  . GLN B 2 2   ? 43.746  -1.268  -0.242  1.00 55.28  ? 2   GLN B OE1  1 
ATOM   2528  N  NE2  . GLN B 2 2   ? 42.853  0.340   -1.532  1.00 44.51  ? 2   GLN B NE2  1 
ATOM   2529  N  N    . ILE B 2 3   ? 43.802  2.105   4.251   1.00 47.15  ? 3   ILE B N    1 
ATOM   2530  C  CA   . ILE B 2 3   ? 43.000  1.524   5.323   1.00 46.68  ? 3   ILE B CA   1 
ATOM   2531  C  C    . ILE B 2 3   ? 41.604  1.205   4.800   1.00 49.40  ? 3   ILE B C    1 
ATOM   2532  O  O    . ILE B 2 3   ? 41.233  1.550   3.675   1.00 49.40  ? 3   ILE B O    1 
ATOM   2533  C  CB   . ILE B 2 3   ? 42.899  2.445   6.547   1.00 44.77  ? 3   ILE B CB   1 
ATOM   2534  C  CG1  . ILE B 2 3   ? 41.969  3.627   6.208   1.00 46.20  ? 3   ILE B CG1  1 
ATOM   2535  C  CG2  . ILE B 2 3   ? 44.246  2.893   6.959   1.00 44.84  ? 3   ILE B CG2  1 
ATOM   2536  C  CD1  . ILE B 2 3   ? 41.676  4.590   7.365   1.00 43.58  ? 3   ILE B CD1  1 
ATOM   2537  N  N    . PHE B 2 4   ? 40.810  0.571   5.654   1.00 47.51  ? 4   PHE B N    1 
ATOM   2538  C  CA   . PHE B 2 4   ? 39.415  0.309   5.362   1.00 42.92  ? 4   PHE B CA   1 
ATOM   2539  C  C    . PHE B 2 4   ? 38.542  1.154   6.280   1.00 46.89  ? 4   PHE B C    1 
ATOM   2540  O  O    . PHE B 2 4   ? 38.956  1.533   7.378   1.00 46.79  ? 4   PHE B O    1 
ATOM   2541  C  CB   . PHE B 2 4   ? 39.105  -1.180  5.520   1.00 42.65  ? 4   PHE B CB   1 
ATOM   2542  C  CG   . PHE B 2 4   ? 39.939  -2.065  4.626   1.00 40.93  ? 4   PHE B CG   1 
ATOM   2543  C  CD1  . PHE B 2 4   ? 39.866  -1.948  3.245   1.00 45.36  ? 4   PHE B CD1  1 
ATOM   2544  C  CD2  . PHE B 2 4   ? 40.815  -2.987  5.167   1.00 44.84  ? 4   PHE B CD2  1 
ATOM   2545  C  CE1  . PHE B 2 4   ? 40.655  -2.750  2.404   1.00 47.65  ? 4   PHE B CE1  1 
ATOM   2546  C  CE2  . PHE B 2 4   ? 41.602  -3.782  4.356   1.00 50.68  ? 4   PHE B CE2  1 
ATOM   2547  C  CZ   . PHE B 2 4   ? 41.525  -3.664  2.956   1.00 48.47  ? 4   PHE B CZ   1 
ATOM   2548  N  N    . VAL B 2 5   ? 37.340  1.481   5.807   1.00 45.12  ? 5   VAL B N    1 
ATOM   2549  C  CA   . VAL B 2 5   ? 36.334  2.169   6.610   1.00 47.22  ? 5   VAL B CA   1 
ATOM   2550  C  C    . VAL B 2 5   ? 35.016  1.424   6.437   1.00 50.61  ? 5   VAL B C    1 
ATOM   2551  O  O    . VAL B 2 5   ? 34.519  1.300   5.310   1.00 47.28  ? 5   VAL B O    1 
ATOM   2552  C  CB   . VAL B 2 5   ? 36.148  3.651   6.221   1.00 45.25  ? 5   VAL B CB   1 
ATOM   2553  C  CG1  . VAL B 2 5   ? 35.068  4.290   7.125   1.00 41.36  ? 5   VAL B CG1  1 
ATOM   2554  C  CG2  . VAL B 2 5   ? 37.452  4.446   6.317   1.00 40.44  ? 5   VAL B CG2  1 
ATOM   2555  N  N    . LYS B 2 6   ? 34.441  0.948   7.546   1.00 41.79  ? 6   LYS B N    1 
ATOM   2556  C  CA   . LYS B 2 6   ? 33.079  0.420   7.512   1.00 49.73  ? 6   LYS B CA   1 
ATOM   2557  C  C    . LYS B 2 6   ? 32.095  1.589   7.594   1.00 51.29  ? 6   LYS B C    1 
ATOM   2558  O  O    . LYS B 2 6   ? 32.103  2.361   8.562   1.00 45.84  ? 6   LYS B O    1 
ATOM   2559  C  CB   . LYS B 2 6   ? 32.831  -0.590  8.638   1.00 43.97  ? 6   LYS B CB   1 
ATOM   2560  C  CG   . LYS B 2 6   ? 33.671  -1.922  8.542   1.00 56.16  ? 6   LYS B CG   1 
ATOM   2561  C  CD   . LYS B 2 6   ? 32.863  -3.153  8.068   1.00 53.06  ? 6   LYS B CD   1 
ATOM   2562  C  CE   . LYS B 2 6   ? 32.038  -3.750  9.228   1.00 59.96  ? 6   LYS B CE   1 
ATOM   2563  N  NZ   . LYS B 2 6   ? 31.049  -4.831  8.820   1.00 63.25  ? 6   LYS B NZ   1 
ATOM   2564  N  N    . THR B 2 7   ? 31.257  1.719   6.572   1.00 50.91  ? 7   THR B N    1 
ATOM   2565  C  CA   . THR B 2 7   ? 30.322  2.823   6.451   1.00 49.64  ? 7   THR B CA   1 
ATOM   2566  C  C    . THR B 2 7   ? 28.995  2.472   7.113   1.00 48.67  ? 7   THR B C    1 
ATOM   2567  O  O    . THR B 2 7   ? 28.744  1.325   7.484   1.00 56.51  ? 7   THR B O    1 
ATOM   2568  C  CB   . THR B 2 7   ? 30.108  3.164   4.981   1.00 44.46  ? 7   THR B CB   1 
ATOM   2569  O  OG1  . THR B 2 7   ? 29.213  2.204   4.410   1.00 50.34  ? 7   THR B OG1  1 
ATOM   2570  C  CG2  . THR B 2 7   ? 31.407  3.083   4.247   1.00 45.44  ? 7   THR B CG2  1 
ATOM   2571  N  N    . LEU B 2 8   ? 28.120  3.475   7.217   1.00 48.73  ? 8   LEU B N    1 
ATOM   2572  C  CA   . LEU B 2 8   ? 26.853  3.327   7.928   1.00 52.01  ? 8   LEU B CA   1 
ATOM   2573  C  C    . LEU B 2 8   ? 25.969  2.232   7.361   1.00 51.29  ? 8   LEU B C    1 
ATOM   2574  O  O    . LEU B 2 8   ? 24.958  1.902   7.989   1.00 55.94  ? 8   LEU B O    1 
ATOM   2575  C  CB   . LEU B 2 8   ? 26.062  4.645   7.920   1.00 50.42  ? 8   LEU B CB   1 
ATOM   2576  C  CG   . LEU B 2 8   ? 26.786  5.919   8.352   1.00 55.45  ? 8   LEU B CG   1 
ATOM   2577  C  CD1  . LEU B 2 8   ? 25.901  7.156   8.161   1.00 57.09  ? 8   LEU B CD1  1 
ATOM   2578  C  CD2  . LEU B 2 8   ? 27.237  5.796   9.796   1.00 47.75  ? 8   LEU B CD2  1 
ATOM   2579  N  N    . THR B 2 9   ? 26.294  1.680   6.197   1.00 51.43  ? 9   THR B N    1 
ATOM   2580  C  CA   . THR B 2 9   ? 25.562  0.540   5.657   1.00 57.43  ? 9   THR B CA   1 
ATOM   2581  C  C    . THR B 2 9   ? 26.231  -0.795  5.969   1.00 56.02  ? 9   THR B C    1 
ATOM   2582  O  O    . THR B 2 9   ? 25.717  -1.841  5.566   1.00 56.61  ? 9   THR B O    1 
ATOM   2583  C  CB   . THR B 2 9   ? 25.392  0.697   4.140   1.00 59.02  ? 9   THR B CB   1 
ATOM   2584  O  OG1  . THR B 2 9   ? 26.675  0.909   3.520   1.00 60.66  ? 9   THR B OG1  1 
ATOM   2585  C  CG2  . THR B 2 9   ? 24.521  1.892   3.856   1.00 50.40  ? 9   THR B CG2  1 
ATOM   2586  N  N    . GLY B 2 10  ? 27.370  -0.789  6.666   1.00 57.87  ? 10  GLY B N    1 
ATOM   2587  C  CA   . GLY B 2 10  ? 28.147  -1.989  6.889   1.00 52.73  ? 10  GLY B CA   1 
ATOM   2588  C  C    . GLY B 2 10  ? 29.151  -2.316  5.799   1.00 55.30  ? 10  GLY B C    1 
ATOM   2589  O  O    . GLY B 2 10  ? 30.059  -3.125  6.038   1.00 57.53  ? 10  GLY B O    1 
ATOM   2590  N  N    . LYS B 2 11  ? 29.010  -1.675  4.638   1.00 51.30  ? 11  LYS B N    1 
ATOM   2591  C  CA   . LYS B 2 11  ? 29.917  -1.906  3.485   1.00 53.77  ? 11  LYS B CA   1 
ATOM   2592  C  C    . LYS B 2 11  ? 31.319  -1.369  3.778   1.00 53.79  ? 11  LYS B C    1 
ATOM   2593  O  O    . LYS B 2 11  ? 31.438  -0.377  4.503   1.00 51.39  ? 11  LYS B O    1 
ATOM   2594  C  CB   . LYS B 2 11  ? 29.346  -1.218  2.246   1.00 50.57  ? 11  LYS B CB   1 
ATOM   2595  C  CG   . LYS B 2 11  ? 30.076  -1.449  0.930   1.00 58.38  ? 11  LYS B CG   1 
ATOM   2596  C  CD   . LYS B 2 11  ? 30.391  -0.164  0.194   1.00 62.47  ? 11  LYS B CD   1 
ATOM   2597  C  CE   . LYS B 2 11  ? 30.885  -0.384  -1.220  1.00 63.29  ? 11  LYS B CE   1 
ATOM   2598  N  NZ   . LYS B 2 11  ? 32.150  -1.156  -1.255  1.00 67.10  ? 11  LYS B NZ   1 
ATOM   2599  N  N    . THR B 2 12  ? 32.332  -2.012  3.206   1.00 44.73  ? 12  THR B N    1 
ATOM   2600  C  CA   . THR B 2 12  ? 33.725  -1.567  3.407   1.00 45.73  ? 12  THR B CA   1 
ATOM   2601  C  C    . THR B 2 12  ? 34.202  -0.748  2.213   1.00 48.54  ? 12  THR B C    1 
ATOM   2602  O  O    . THR B 2 12  ? 34.086  -1.224  1.079   1.00 53.28  ? 12  THR B O    1 
ATOM   2603  C  CB   . THR B 2 12  ? 34.665  -2.744  3.674   1.00 48.05  ? 12  THR B CB   1 
ATOM   2604  O  OG1  . THR B 2 12  ? 34.306  -3.305  4.934   1.00 49.01  ? 12  THR B OG1  1 
ATOM   2605  C  CG2  . THR B 2 12  ? 36.124  -2.351  3.683   1.00 43.45  ? 12  THR B CG2  1 
ATOM   2606  N  N    . ILE B 2 13  ? 34.686  0.456   2.485   1.00 43.90  ? 13  ILE B N    1 
ATOM   2607  C  CA   . ILE B 2 13  ? 35.299  1.279   1.419   1.00 47.88  ? 13  ILE B CA   1 
ATOM   2608  C  C    . ILE B 2 13  ? 36.782  1.414   1.749   1.00 45.75  ? 13  ILE B C    1 
ATOM   2609  O  O    . ILE B 2 13  ? 37.138  1.333   2.927   1.00 44.72  ? 13  ILE B O    1 
ATOM   2610  C  CB   . ILE B 2 13  ? 34.612  2.656   1.303   1.00 50.03  ? 13  ILE B CB   1 
ATOM   2611  C  CG1  . ILE B 2 13  ? 34.701  3.467   2.597   1.00 53.63  ? 13  ILE B CG1  1 
ATOM   2612  C  CG2  . ILE B 2 13  ? 33.177  2.512   0.826   1.00 51.81  ? 13  ILE B CG2  1 
ATOM   2613  C  CD1  . ILE B 2 13  ? 35.162  4.885   2.400   1.00 51.42  ? 13  ILE B CD1  1 
ATOM   2614  N  N    . THR B 2 14  ? 37.632  1.546   0.736   1.00 47.18  ? 14  THR B N    1 
ATOM   2615  C  CA   . THR B 2 14  ? 39.034  1.846   1.007   1.00 49.03  ? 14  THR B CA   1 
ATOM   2616  C  C    . THR B 2 14  ? 39.205  3.351   1.187   1.00 49.08  ? 14  THR B C    1 
ATOM   2617  O  O    . THR B 2 14  ? 38.434  4.149   0.646   1.00 50.80  ? 14  THR B O    1 
ATOM   2618  C  CB   . THR B 2 14  ? 39.955  1.333   -0.109  1.00 45.97  ? 14  THR B CB   1 
ATOM   2619  O  OG1  . THR B 2 14  ? 39.535  1.867   -1.363  1.00 52.44  ? 14  THR B OG1  1 
ATOM   2620  C  CG2  . THR B 2 14  ? 39.929  -0.212  -0.198  1.00 42.80  ? 14  THR B CG2  1 
ATOM   2621  N  N    . LEU B 2 15  ? 40.195  3.732   1.992   1.00 45.77  ? 15  LEU B N    1 
ATOM   2622  C  CA   . LEU B 2 15  ? 40.557  5.127   2.181   1.00 42.12  ? 15  LEU B CA   1 
ATOM   2623  C  C    . LEU B 2 15  ? 42.070  5.272   2.066   1.00 47.78  ? 15  LEU B C    1 
ATOM   2624  O  O    . LEU B 2 15  ? 42.830  4.458   2.600   1.00 50.98  ? 15  LEU B O    1 
ATOM   2625  C  CB   . LEU B 2 15  ? 40.071  5.681   3.538   1.00 48.40  ? 15  LEU B CB   1 
ATOM   2626  C  CG   . LEU B 2 15  ? 39.733  7.192   3.534   1.00 48.11  ? 15  LEU B CG   1 
ATOM   2627  C  CD1  . LEU B 2 15  ? 38.462  7.465   2.749   1.00 43.14  ? 15  LEU B CD1  1 
ATOM   2628  C  CD2  . LEU B 2 15  ? 39.646  7.803   4.929   1.00 44.45  ? 15  LEU B CD2  1 
ATOM   2629  N  N    . GLU B 2 16  ? 42.494  6.310   1.341   1.00 52.04  ? 16  GLU B N    1 
ATOM   2630  C  CA   . GLU B 2 16  ? 43.892  6.550   1.015   1.00 50.73  ? 16  GLU B CA   1 
ATOM   2631  C  C    . GLU B 2 16  ? 44.404  7.601   1.981   1.00 51.92  ? 16  GLU B C    1 
ATOM   2632  O  O    . GLU B 2 16  ? 43.985  8.763   1.929   1.00 55.86  ? 16  GLU B O    1 
ATOM   2633  C  CB   . GLU B 2 16  ? 44.050  6.992   -0.437  1.00 45.74  ? 16  GLU B CB   1 
ATOM   2634  C  CG   . GLU B 2 16  ? 45.478  7.308   -0.809  1.00 47.59  ? 16  GLU B CG   1 
ATOM   2635  C  CD   . GLU B 2 16  ? 46.425  6.250   -0.316  1.00 53.04  ? 16  GLU B CD   1 
ATOM   2636  O  OE1  . GLU B 2 16  ? 46.176  5.054   -0.614  1.00 54.16  ? 16  GLU B OE1  1 
ATOM   2637  O  OE2  . GLU B 2 16  ? 47.400  6.613   0.380   1.00 58.01  ? 16  GLU B OE2  1 
ATOM   2638  N  N    . VAL B 2 17  ? 45.285  7.185   2.884   1.00 49.92  ? 17  VAL B N    1 
ATOM   2639  C  CA   . VAL B 2 17  ? 45.648  7.990   4.039   1.00 53.05  ? 17  VAL B CA   1 
ATOM   2640  C  C    . VAL B 2 17  ? 47.138  7.830   4.320   1.00 58.34  ? 17  VAL B C    1 
ATOM   2641  O  O    . VAL B 2 17  ? 47.823  6.961   3.768   1.00 54.45  ? 17  VAL B O    1 
ATOM   2642  C  CB   . VAL B 2 17  ? 44.819  7.592   5.274   1.00 56.99  ? 17  VAL B CB   1 
ATOM   2643  C  CG1  . VAL B 2 17  ? 43.366  8.086   5.120   1.00 50.63  ? 17  VAL B CG1  1 
ATOM   2644  C  CG2  . VAL B 2 17  ? 44.851  6.077   5.432   1.00 47.49  ? 17  VAL B CG2  1 
ATOM   2645  N  N    . GLU B 2 18  ? 47.629  8.688   5.203   1.00 59.79  ? 18  GLU B N    1 
ATOM   2646  C  CA   . GLU B 2 18  ? 49.032  8.741   5.565   1.00 63.20  ? 18  GLU B CA   1 
ATOM   2647  C  C    . GLU B 2 18  ? 49.132  8.764   7.086   1.00 58.58  ? 18  GLU B C    1 
ATOM   2648  O  O    . GLU B 2 18  ? 48.304  9.402   7.753   1.00 59.36  ? 18  GLU B O    1 
ATOM   2649  C  CB   . GLU B 2 18  ? 49.707  9.995   4.947   1.00 62.31  ? 18  GLU B CB   1 
ATOM   2650  C  CG   . GLU B 2 18  ? 51.011  9.743   4.184   1.00 56.48  ? 18  GLU B CG   1 
ATOM   2651  C  CD   . GLU B 2 18  ? 50.884  8.661   3.136   1.00 64.88  ? 18  GLU B CD   1 
ATOM   2652  O  OE1  . GLU B 2 18  ? 51.498  7.584   3.331   1.00 67.59  ? 18  GLU B OE1  1 
ATOM   2653  O  OE2  . GLU B 2 18  ? 50.174  8.871   2.115   1.00 64.72  ? 18  GLU B OE2  1 
ATOM   2654  N  N    . PRO B 2 19  ? 50.119  8.072   7.667   1.00 55.49  ? 19  PRO B N    1 
ATOM   2655  C  CA   . PRO B 2 19  ? 50.286  8.099   9.128   1.00 54.22  ? 19  PRO B CA   1 
ATOM   2656  C  C    . PRO B 2 19  ? 50.233  9.492   9.722   1.00 56.93  ? 19  PRO B C    1 
ATOM   2657  O  O    . PRO B 2 19  ? 49.834  9.656   10.872  1.00 56.59  ? 19  PRO B O    1 
ATOM   2658  C  CB   . PRO B 2 19  ? 51.666  7.458   9.329   1.00 48.89  ? 19  PRO B CB   1 
ATOM   2659  C  CG   . PRO B 2 19  ? 51.768  6.467   8.216   1.00 46.48  ? 19  PRO B CG   1 
ATOM   2660  C  CD   . PRO B 2 19  ? 51.057  7.129   7.027   1.00 57.64  ? 19  PRO B CD   1 
ATOM   2661  N  N    . SER B 2 20  ? 50.597  10.503  8.935   1.00 61.50  ? 20  SER B N    1 
ATOM   2662  C  CA   . SER B 2 20  ? 50.603  11.880  9.420   1.00 63.33  ? 20  SER B CA   1 
ATOM   2663  C  C    . SER B 2 20  ? 49.196  12.466  9.571   1.00 57.43  ? 20  SER B C    1 
ATOM   2664  O  O    . SER B 2 20  ? 49.002  13.402  10.356  1.00 58.30  ? 20  SER B O    1 
ATOM   2665  C  CB   . SER B 2 20  ? 51.429  12.742  8.458   1.00 59.99  ? 20  SER B CB   1 
ATOM   2666  O  OG   . SER B 2 20  ? 51.262  12.279  7.125   1.00 74.09  ? 20  SER B OG   1 
ATOM   2667  N  N    . ASP B 2 21  ? 48.224  11.984  8.797   1.00 61.17  ? 21  ASP B N    1 
ATOM   2668  C  CA   . ASP B 2 21  ? 46.918  12.637  8.734   1.00 60.31  ? 21  ASP B CA   1 
ATOM   2669  C  C    . ASP B 2 21  ? 46.296  12.762  10.118  1.00 57.42  ? 21  ASP B C    1 
ATOM   2670  O  O    . ASP B 2 21  ? 46.352  11.835  10.922  1.00 53.99  ? 21  ASP B O    1 
ATOM   2671  C  CB   . ASP B 2 21  ? 45.986  11.847  7.812   1.00 56.63  ? 21  ASP B CB   1 
ATOM   2672  C  CG   . ASP B 2 21  ? 46.427  11.900  6.374   1.00 60.92  ? 21  ASP B CG   1 
ATOM   2673  O  OD1  . ASP B 2 21  ? 47.027  12.936  6.008   1.00 64.96  ? 21  ASP B OD1  1 
ATOM   2674  O  OD2  . ASP B 2 21  ? 46.192  10.919  5.624   1.00 57.78  ? 21  ASP B OD2  1 
ATOM   2675  N  N    . THR B 2 22  ? 45.721  13.924  10.408  1.00 56.51  ? 22  THR B N    1 
ATOM   2676  C  CA   . THR B 2 22  ? 44.989  14.043  11.656  1.00 56.04  ? 22  THR B CA   1 
ATOM   2677  C  C    . THR B 2 22  ? 43.609  13.406  11.498  1.00 56.79  ? 22  THR B C    1 
ATOM   2678  O  O    . THR B 2 22  ? 43.196  13.030  10.399  1.00 55.84  ? 22  THR B O    1 
ATOM   2679  C  CB   . THR B 2 22  ? 44.865  15.510  12.076  1.00 58.63  ? 22  THR B CB   1 
ATOM   2680  O  OG1  . THR B 2 22  ? 43.719  16.099  11.448  1.00 64.20  ? 22  THR B OG1  1 
ATOM   2681  C  CG2  . THR B 2 22  ? 46.098  16.284  11.665  1.00 57.43  ? 22  THR B CG2  1 
ATOM   2682  N  N    . ILE B 2 23  ? 42.880  13.285  12.610  1.00 50.12  ? 23  ILE B N    1 
ATOM   2683  C  CA   . ILE B 2 23  ? 41.564  12.663  12.501  1.00 53.95  ? 23  ILE B CA   1 
ATOM   2684  C  C    . ILE B 2 23  ? 40.634  13.530  11.646  1.00 55.73  ? 23  ILE B C    1 
ATOM   2685  O  O    . ILE B 2 23  ? 39.805  13.002  10.886  1.00 57.26  ? 23  ILE B O    1 
ATOM   2686  C  CB   . ILE B 2 23  ? 40.988  12.358  13.904  1.00 51.85  ? 23  ILE B CB   1 
ATOM   2687  C  CG1  . ILE B 2 23  ? 41.823  11.282  14.598  1.00 51.00  ? 23  ILE B CG1  1 
ATOM   2688  C  CG2  . ILE B 2 23  ? 39.565  11.850  13.834  1.00 51.04  ? 23  ILE B CG2  1 
ATOM   2689  C  CD1  . ILE B 2 23  ? 42.356  10.200  13.669  1.00 52.87  ? 23  ILE B CD1  1 
ATOM   2690  N  N    . GLU B 2 24  ? 40.791  14.857  11.706  1.00 52.80  ? 24  GLU B N    1 
ATOM   2691  C  CA   . GLU B 2 24  ? 40.031  15.744  10.828  1.00 53.12  ? 24  GLU B CA   1 
ATOM   2692  C  C    . GLU B 2 24  ? 40.337  15.478  9.360   1.00 56.49  ? 24  GLU B C    1 
ATOM   2693  O  O    . GLU B 2 24  ? 39.426  15.489  8.520   1.00 55.36  ? 24  GLU B O    1 
ATOM   2694  C  CB   . GLU B 2 24  ? 40.326  17.198  11.178  1.00 53.21  ? 24  GLU B CB   1 
ATOM   2695  C  CG   . GLU B 2 24  ? 40.017  17.532  12.644  1.00 58.95  ? 24  GLU B CG   1 
ATOM   2696  C  CD   . GLU B 2 24  ? 41.264  17.565  13.553  1.00 65.19  ? 24  GLU B CD   1 
ATOM   2697  O  OE1  . GLU B 2 24  ? 41.396  18.543  14.330  1.00 70.86  ? 24  GLU B OE1  1 
ATOM   2698  O  OE2  . GLU B 2 24  ? 42.104  16.624  13.503  1.00 64.07  ? 24  GLU B OE2  1 
ATOM   2699  N  N    . ASN B 2 25  ? 41.610  15.227  9.026   1.00 53.86  ? 25  ASN B N    1 
ATOM   2700  C  CA   . ASN B 2 25  ? 41.951  14.873  7.646   1.00 51.37  ? 25  ASN B CA   1 
ATOM   2701  C  C    . ASN B 2 25  ? 41.196  13.626  7.196   1.00 54.85  ? 25  ASN B C    1 
ATOM   2702  O  O    . ASN B 2 25  ? 40.675  13.563  6.071   1.00 51.78  ? 25  ASN B O    1 
ATOM   2703  C  CB   . ASN B 2 25  ? 43.451  14.616  7.498   1.00 51.23  ? 25  ASN B CB   1 
ATOM   2704  C  CG   . ASN B 2 25  ? 44.308  15.820  7.824   1.00 62.92  ? 25  ASN B CG   1 
ATOM   2705  O  OD1  . ASN B 2 25  ? 45.525  15.672  8.039   1.00 60.89  ? 25  ASN B OD1  1 
ATOM   2706  N  ND2  . ASN B 2 25  ? 43.696  17.017  7.868   1.00 53.86  ? 25  ASN B ND2  1 
ATOM   2707  N  N    . VAL B 2 26  ? 41.150  12.612  8.051   1.00 53.64  ? 26  VAL B N    1 
ATOM   2708  C  CA   . VAL B 2 26  ? 40.495  11.330  7.676   1.00 50.39  ? 26  VAL B CA   1 
ATOM   2709  C  C    . VAL B 2 26  ? 38.999  11.596  7.574   1.00 47.90  ? 26  VAL B C    1 
ATOM   2710  O  O    . VAL B 2 26  ? 38.405  11.176  6.586   1.00 49.06  ? 26  VAL B O    1 
ATOM   2711  C  CB   . VAL B 2 26  ? 40.860  10.217  8.676   1.00 46.96  ? 26  VAL B CB   1 
ATOM   2712  C  CG1  . VAL B 2 26  ? 40.063  8.942   8.469   1.00 41.24  ? 26  VAL B CG1  1 
ATOM   2713  C  CG2  . VAL B 2 26  ? 42.346  9.933   8.649   1.00 43.84  ? 26  VAL B CG2  1 
ATOM   2714  N  N    . LYS B 2 27  ? 38.432  12.306  8.547   1.00 49.43  ? 27  LYS B N    1 
ATOM   2715  C  CA   . LYS B 2 27  ? 37.020  12.672  8.446   1.00 51.30  ? 27  LYS B CA   1 
ATOM   2716  C  C    . LYS B 2 27  ? 36.732  13.452  7.165   1.00 52.69  ? 27  LYS B C    1 
ATOM   2717  O  O    . LYS B 2 27  ? 35.662  13.283  6.554   1.00 49.25  ? 27  LYS B O    1 
ATOM   2718  C  CB   . LYS B 2 27  ? 36.587  13.493  9.656   1.00 45.50  ? 27  LYS B CB   1 
ATOM   2719  C  CG   . LYS B 2 27  ? 36.210  12.709  10.885  1.00 47.66  ? 27  LYS B CG   1 
ATOM   2720  C  CD   . LYS B 2 27  ? 36.288  13.606  12.168  1.00 52.00  ? 27  LYS B CD   1 
ATOM   2721  C  CE   . LYS B 2 27  ? 35.636  12.941  13.404  1.00 45.98  ? 27  LYS B CE   1 
ATOM   2722  N  NZ   . LYS B 2 27  ? 35.626  13.802  14.623  1.00 42.45  ? 27  LYS B NZ   1 
ATOM   2723  N  N    . ALA B 2 28  ? 37.675  14.298  6.740   1.00 48.68  ? 28  ALA B N    1 
ATOM   2724  C  CA   . ALA B 2 28  ? 37.500  15.023  5.488   1.00 51.31  ? 28  ALA B CA   1 
ATOM   2725  C  C    . ALA B 2 28  ? 37.570  14.074  4.311   1.00 47.28  ? 28  ALA B C    1 
ATOM   2726  O  O    . ALA B 2 28  ? 36.800  14.206  3.357   1.00 52.83  ? 28  ALA B O    1 
ATOM   2727  C  CB   . ALA B 2 28  ? 38.549  16.133  5.348   1.00 46.17  ? 28  ALA B CB   1 
ATOM   2728  N  N    . LYS B 2 29  ? 38.479  13.104  4.352   1.00 49.61  ? 29  LYS B N    1 
ATOM   2729  C  CA   . LYS B 2 29  ? 38.546  12.165  3.236   1.00 46.67  ? 29  LYS B CA   1 
ATOM   2730  C  C    . LYS B 2 29  ? 37.298  11.283  3.181   1.00 46.82  ? 29  LYS B C    1 
ATOM   2731  O  O    . LYS B 2 29  ? 36.821  10.956  2.089   1.00 48.33  ? 29  LYS B O    1 
ATOM   2732  C  CB   . LYS B 2 29  ? 39.829  11.338  3.337   1.00 50.05  ? 29  LYS B CB   1 
ATOM   2733  C  CG   . LYS B 2 29  ? 41.111  12.179  3.137   1.00 48.68  ? 29  LYS B CG   1 
ATOM   2734  C  CD   . LYS B 2 29  ? 42.371  11.493  3.662   1.00 51.68  ? 29  LYS B CD   1 
ATOM   2735  C  CE   . LYS B 2 29  ? 43.649  12.007  2.990   1.00 43.84  ? 29  LYS B CE   1 
ATOM   2736  N  NZ   . LYS B 2 29  ? 43.482  11.983  1.503   1.00 60.53  ? 29  LYS B NZ   1 
ATOM   2737  N  N    . ILE B 2 30  ? 36.731  10.921  4.337   1.00 45.92  ? 30  ILE B N    1 
ATOM   2738  C  CA   . ILE B 2 30  ? 35.484  10.159  4.330   1.00 48.72  ? 30  ILE B CA   1 
ATOM   2739  C  C    . ILE B 2 30  ? 34.365  10.999  3.721   1.00 53.43  ? 30  ILE B C    1 
ATOM   2740  O  O    . ILE B 2 30  ? 33.517  10.488  2.977   1.00 45.55  ? 30  ILE B O    1 
ATOM   2741  C  CB   . ILE B 2 30  ? 35.121  9.679   5.749   1.00 47.18  ? 30  ILE B CB   1 
ATOM   2742  C  CG1  . ILE B 2 30  ? 36.088  8.595   6.224   1.00 50.22  ? 30  ILE B CG1  1 
ATOM   2743  C  CG2  . ILE B 2 30  ? 33.686  9.163   5.795   1.00 38.51  ? 30  ILE B CG2  1 
ATOM   2744  C  CD1  . ILE B 2 30  ? 35.935  8.237   7.720   1.00 46.07  ? 30  ILE B CD1  1 
ATOM   2745  N  N    . GLN B 2 31  ? 34.345  12.304  4.017   1.00 48.41  ? 31  GLN B N    1 
ATOM   2746  C  CA   . GLN B 2 31  ? 33.375  13.159  3.342   1.00 53.34  ? 31  GLN B CA   1 
ATOM   2747  C  C    . GLN B 2 31  ? 33.553  13.086  1.826   1.00 53.80  ? 31  GLN B C    1 
ATOM   2748  O  O    . GLN B 2 31  ? 32.587  12.895  1.075   1.00 50.80  ? 31  GLN B O    1 
ATOM   2749  C  CB   . GLN B 2 31  ? 33.504  14.597  3.839   1.00 56.14  ? 31  GLN B CB   1 
ATOM   2750  C  CG   . GLN B 2 31  ? 32.772  15.621  2.971   1.00 55.76  ? 31  GLN B CG   1 
ATOM   2751  C  CD   . GLN B 2 31  ? 32.635  16.969  3.665   1.00 62.91  ? 31  GLN B CD   1 
ATOM   2752  O  OE1  . GLN B 2 31  ? 33.618  17.548  4.160   1.00 67.66  ? 31  GLN B OE1  1 
ATOM   2753  N  NE2  . GLN B 2 31  ? 31.406  17.463  3.729   1.00 64.72  ? 31  GLN B NE2  1 
ATOM   2754  N  N    . ASP B 2 32  ? 34.797  13.196  1.363   1.00 52.41  ? 32  ASP B N    1 
ATOM   2755  C  CA   . ASP B 2 32  ? 35.055  13.177  -0.070  1.00 44.36  ? 32  ASP B CA   1 
ATOM   2756  C  C    . ASP B 2 32  ? 34.544  11.896  -0.723  1.00 49.49  ? 32  ASP B C    1 
ATOM   2757  O  O    . ASP B 2 32  ? 34.048  11.933  -1.854  1.00 54.34  ? 32  ASP B O    1 
ATOM   2758  C  CB   . ASP B 2 32  ? 36.546  13.345  -0.331  1.00 42.67  ? 32  ASP B CB   1 
ATOM   2759  C  CG   . ASP B 2 32  ? 36.914  13.065  -1.779  1.00 47.84  ? 32  ASP B CG   1 
ATOM   2760  O  OD1  . ASP B 2 32  ? 36.668  13.948  -2.635  1.00 53.16  ? 32  ASP B OD1  1 
ATOM   2761  O  OD2  . ASP B 2 32  ? 37.426  11.961  -2.070  1.00 46.30  ? 32  ASP B OD2  1 
ATOM   2762  N  N    . LYS B 2 33  ? 34.649  10.753  -0.044  1.00 49.96  ? 33  LYS B N    1 
ATOM   2763  C  CA   . LYS B 2 33  ? 34.268  9.503   -0.697  1.00 46.20  ? 33  LYS B CA   1 
ATOM   2764  C  C    . LYS B 2 33  ? 32.852  9.044   -0.352  1.00 50.60  ? 33  LYS B C    1 
ATOM   2765  O  O    . LYS B 2 33  ? 32.173  8.458   -1.210  1.00 51.57  ? 33  LYS B O    1 
ATOM   2766  C  CB   . LYS B 2 33  ? 35.276  8.392   -0.358  1.00 47.35  ? 33  LYS B CB   1 
ATOM   2767  C  CG   . LYS B 2 33  ? 35.230  7.180   -1.314  1.00 48.14  ? 33  LYS B CG   1 
ATOM   2768  C  CD   . LYS B 2 33  ? 36.592  6.530   -1.479  1.00 46.46  ? 33  LYS B CD   1 
ATOM   2769  C  CE   . LYS B 2 33  ? 36.472  5.170   -2.139  1.00 51.07  ? 33  LYS B CE   1 
ATOM   2770  N  NZ   . LYS B 2 33  ? 37.750  4.384   -2.022  1.00 49.00  ? 33  LYS B NZ   1 
ATOM   2771  N  N    . GLU B 2 34  ? 32.384  9.293   0.877   1.00 43.60  ? 34  GLU B N    1 
ATOM   2772  C  CA   . GLU B 2 34  ? 31.072  8.838   1.322   1.00 52.63  ? 34  GLU B CA   1 
ATOM   2773  C  C    . GLU B 2 34  ? 30.052  9.956   1.504   1.00 50.59  ? 34  GLU B C    1 
ATOM   2774  O  O    . GLU B 2 34  ? 28.863  9.658   1.621   1.00 48.60  ? 34  GLU B O    1 
ATOM   2775  C  CB   . GLU B 2 34  ? 31.181  8.068   2.653   1.00 46.49  ? 34  GLU B CB   1 
ATOM   2776  C  CG   . GLU B 2 34  ? 31.432  6.601   2.513   1.00 50.59  ? 34  GLU B CG   1 
ATOM   2777  C  CD   . GLU B 2 34  ? 30.239  5.832   1.937   1.00 53.53  ? 34  GLU B CD   1 
ATOM   2778  O  OE1  . GLU B 2 34  ? 29.202  5.762   2.613   1.00 49.73  ? 34  GLU B OE1  1 
ATOM   2779  O  OE2  . GLU B 2 34  ? 30.351  5.259   0.823   1.00 57.41  ? 34  GLU B OE2  1 
ATOM   2780  N  N    . GLY B 2 35  ? 30.481  11.218  1.564   1.00 50.15  ? 35  GLY B N    1 
ATOM   2781  C  CA   . GLY B 2 35  ? 29.575  12.336  1.629   1.00 43.37  ? 35  GLY B CA   1 
ATOM   2782  C  C    . GLY B 2 35  ? 29.146  12.743  3.020   1.00 56.44  ? 35  GLY B C    1 
ATOM   2783  O  O    . GLY B 2 35  ? 28.451  13.760  3.161   1.00 66.65  ? 35  GLY B O    1 
ATOM   2784  N  N    . ILE B 2 36  ? 29.519  11.993  4.046   1.00 52.27  ? 36  ILE B N    1 
ATOM   2785  C  CA   . ILE B 2 36  ? 29.111  12.350  5.406   1.00 53.12  ? 36  ILE B CA   1 
ATOM   2786  C  C    . ILE B 2 36  ? 29.847  13.613  5.841   1.00 55.57  ? 36  ILE B C    1 
ATOM   2787  O  O    . ILE B 2 36  ? 31.092  13.654  5.786   1.00 55.07  ? 36  ILE B O    1 
ATOM   2788  C  CB   . ILE B 2 36  ? 29.391  11.203  6.371   1.00 51.10  ? 36  ILE B CB   1 
ATOM   2789  C  CG1  . ILE B 2 36  ? 29.009  9.849   5.750   1.00 57.50  ? 36  ILE B CG1  1 
ATOM   2790  C  CG2  . ILE B 2 36  ? 28.675  11.462  7.707   1.00 47.39  ? 36  ILE B CG2  1 
ATOM   2791  C  CD1  . ILE B 2 36  ? 27.554  9.703   5.354   1.00 56.34  ? 36  ILE B CD1  1 
ATOM   2792  N  N    . PRO B 2 37  ? 29.142  14.640  6.295   1.00 52.92  ? 37  PRO B N    1 
ATOM   2793  C  CA   . PRO B 2 37  ? 29.810  15.819  6.887   1.00 60.71  ? 37  PRO B CA   1 
ATOM   2794  C  C    . PRO B 2 37  ? 30.675  15.437  8.081   1.00 57.01  ? 37  PRO B C    1 
ATOM   2795  O  O    . PRO B 2 37  ? 30.218  14.728  8.994   1.00 60.06  ? 37  PRO B O    1 
ATOM   2796  C  CB   . PRO B 2 37  ? 28.634  16.713  7.318   1.00 57.84  ? 37  PRO B CB   1 
ATOM   2797  C  CG   . PRO B 2 37  ? 27.487  16.279  6.471   1.00 62.79  ? 37  PRO B CG   1 
ATOM   2798  C  CD   . PRO B 2 37  ? 27.685  14.801  6.210   1.00 61.26  ? 37  PRO B CD   1 
ATOM   2799  N  N    . PRO B 2 38  ? 31.928  15.900  8.113   1.00 52.50  ? 38  PRO B N    1 
ATOM   2800  C  CA   . PRO B 2 38  ? 32.791  15.629  9.277   1.00 57.96  ? 38  PRO B CA   1 
ATOM   2801  C  C    . PRO B 2 38  ? 32.126  15.883  10.624  1.00 61.16  ? 38  PRO B C    1 
ATOM   2802  O  O    . PRO B 2 38  ? 32.381  15.140  11.582  1.00 62.33  ? 38  PRO B O    1 
ATOM   2803  C  CB   . PRO B 2 38  ? 33.972  16.590  9.052   1.00 57.23  ? 38  PRO B CB   1 
ATOM   2804  C  CG   . PRO B 2 38  ? 34.021  16.816  7.579   1.00 49.13  ? 38  PRO B CG   1 
ATOM   2805  C  CD   . PRO B 2 38  ? 32.633  16.643  7.049   1.00 57.08  ? 38  PRO B CD   1 
ATOM   2806  N  N    . ASP B 2 39  ? 31.282  16.914  10.725  1.00 60.34  ? 39  ASP B N    1 
ATOM   2807  C  CA   . ASP B 2 39  ? 30.696  17.278  12.014  1.00 64.31  ? 39  ASP B CA   1 
ATOM   2808  C  C    . ASP B 2 39  ? 29.895  16.135  12.621  1.00 62.14  ? 39  ASP B C    1 
ATOM   2809  O  O    . ASP B 2 39  ? 29.689  16.106  13.837  1.00 65.74  ? 39  ASP B O    1 
ATOM   2810  C  CB   . ASP B 2 39  ? 29.784  18.502  11.867  1.00 68.10  ? 39  ASP B CB   1 
ATOM   2811  C  CG   . ASP B 2 39  ? 30.547  19.775  11.561  1.00 78.19  ? 39  ASP B CG   1 
ATOM   2812  O  OD1  . ASP B 2 39  ? 31.765  19.833  11.861  1.00 75.69  ? 39  ASP B OD1  1 
ATOM   2813  O  OD2  . ASP B 2 39  ? 29.917  20.717  11.016  1.00 82.34  ? 39  ASP B OD2  1 
ATOM   2814  N  N    . GLN B 2 40  ? 29.403  15.211  11.796  1.00 59.74  ? 40  GLN B N    1 
ATOM   2815  C  CA   . GLN B 2 40  ? 28.575  14.112  12.270  1.00 57.88  ? 40  GLN B CA   1 
ATOM   2816  C  C    . GLN B 2 40  ? 29.325  12.791  12.396  1.00 52.69  ? 40  GLN B C    1 
ATOM   2817  O  O    . GLN B 2 40  ? 28.789  11.854  12.991  1.00 55.08  ? 40  GLN B O    1 
ATOM   2818  C  CB   . GLN B 2 40  ? 27.374  13.917  11.334  1.00 55.14  ? 40  GLN B CB   1 
ATOM   2819  C  CG   . GLN B 2 40  ? 26.322  14.976  11.480  1.00 64.16  ? 40  GLN B CG   1 
ATOM   2820  C  CD   . GLN B 2 40  ? 26.375  15.997  10.367  1.00 76.04  ? 40  GLN B CD   1 
ATOM   2821  O  OE1  . GLN B 2 40  ? 27.225  16.907  10.362  1.00 72.91  ? 40  GLN B OE1  1 
ATOM   2822  N  NE2  . GLN B 2 40  ? 25.457  15.859  9.407   1.00 79.03  ? 40  GLN B NE2  1 
ATOM   2823  N  N    . GLN B 2 41  ? 30.532  12.684  11.847  1.00 50.64  ? 41  GLN B N    1 
ATOM   2824  C  CA   . GLN B 2 41  ? 31.273  11.429  11.893  1.00 51.15  ? 41  GLN B CA   1 
ATOM   2825  C  C    . GLN B 2 41  ? 31.848  11.153  13.284  1.00 50.84  ? 41  GLN B C    1 
ATOM   2826  O  O    . GLN B 2 41  ? 32.505  12.008  13.890  1.00 47.79  ? 41  GLN B O    1 
ATOM   2827  C  CB   . GLN B 2 41  ? 32.412  11.452  10.873  1.00 44.44  ? 41  GLN B CB   1 
ATOM   2828  C  CG   . GLN B 2 41  ? 31.978  11.789  9.482   1.00 50.20  ? 41  GLN B CG   1 
ATOM   2829  C  CD   . GLN B 2 41  ? 33.138  11.805  8.532   1.00 51.64  ? 41  GLN B CD   1 
ATOM   2830  O  OE1  . GLN B 2 41  ? 34.131  11.122  8.766   1.00 48.34  ? 41  GLN B OE1  1 
ATOM   2831  N  NE2  . GLN B 2 41  ? 33.039  12.600  7.465   1.00 49.12  ? 41  GLN B NE2  1 
ATOM   2832  N  N    . ARG B 2 42  ? 31.720  9.887   13.676  1.00 50.54  ? 42  ARG B N    1 
ATOM   2833  C  CA   . ARG B 2 42  ? 32.419  9.367   14.871  1.00 50.42  ? 42  ARG B CA   1 
ATOM   2834  C  C    . ARG B 2 42  ? 33.134  8.110   14.351  1.00 47.07  ? 42  ARG B C    1 
ATOM   2835  O  O    . ARG B 2 42  ? 32.482  7.315   13.671  1.00 45.36  ? 42  ARG B O    1 
ATOM   2836  C  CB   . ARG B 2 42  ? 31.465  9.086   16.027  1.00 46.62  ? 42  ARG B CB   1 
ATOM   2837  C  CG   . ARG B 2 42  ? 30.610  10.259  16.477  1.00 50.84  ? 42  ARG B CG   1 
ATOM   2838  C  CD   . ARG B 2 42  ? 29.615  9.775   17.510  1.00 47.66  ? 42  ARG B CD   1 
ATOM   2839  N  NE   . ARG B 2 42  ? 30.174  8.667   18.256  1.00 55.13  ? 42  ARG B NE   1 
ATOM   2840  C  CZ   . ARG B 2 42  ? 29.528  7.582   18.644  1.00 53.19  ? 42  ARG B CZ   1 
ATOM   2841  N  NH1  . ARG B 2 42  ? 28.241  7.431   18.392  1.00 46.61  ? 42  ARG B NH1  1 
ATOM   2842  N  NH2  . ARG B 2 42  ? 30.191  6.650   19.296  1.00 53.77  ? 42  ARG B NH2  1 
ATOM   2843  N  N    . LEU B 2 43  ? 34.419  7.935   14.631  1.00 42.07  ? 43  LEU B N    1 
ATOM   2844  C  CA   . LEU B 2 43  ? 35.244  6.858   14.098  1.00 43.99  ? 43  LEU B CA   1 
ATOM   2845  C  C    . LEU B 2 43  ? 35.698  5.942   15.230  1.00 46.94  ? 43  LEU B C    1 
ATOM   2846  O  O    . LEU B 2 43  ? 36.402  6.395   16.144  1.00 47.41  ? 43  LEU B O    1 
ATOM   2847  C  CB   . LEU B 2 43  ? 36.445  7.441   13.364  1.00 37.95  ? 43  LEU B CB   1 
ATOM   2848  C  CG   . LEU B 2 43  ? 36.113  8.184   12.067  1.00 42.50  ? 43  LEU B CG   1 
ATOM   2849  C  CD1  . LEU B 2 43  ? 37.369  8.861   11.510  1.00 40.23  ? 43  LEU B CD1  1 
ATOM   2850  C  CD2  . LEU B 2 43  ? 35.560  7.205   11.065  1.00 40.75  ? 43  LEU B CD2  1 
ATOM   2851  N  N    . ILE B 2 44  ? 35.312  4.654   15.168  1.00 42.60  ? 44  ILE B N    1 
ATOM   2852  C  CA   . ILE B 2 44  ? 35.656  3.681   16.214  1.00 43.31  ? 44  ILE B CA   1 
ATOM   2853  C  C    . ILE B 2 44  ? 36.770  2.764   15.723  1.00 45.64  ? 44  ILE B C    1 
ATOM   2854  O  O    . ILE B 2 44  ? 36.652  2.139   14.660  1.00 47.76  ? 44  ILE B O    1 
ATOM   2855  C  CB   . ILE B 2 44  ? 34.442  2.840   16.657  1.00 46.27  ? 44  ILE B CB   1 
ATOM   2856  C  CG1  . ILE B 2 44  ? 33.202  3.703   16.903  1.00 44.68  ? 44  ILE B CG1  1 
ATOM   2857  C  CG2  . ILE B 2 44  ? 34.778  2.157   17.976  1.00 48.19  ? 44  ILE B CG2  1 
ATOM   2858  C  CD1  . ILE B 2 44  ? 33.261  4.492   18.220  1.00 45.23  ? 44  ILE B CD1  1 
ATOM   2859  N  N    . PHE B 2 45  ? 37.862  2.712   16.490  1.00 46.44  ? 45  PHE B N    1 
ATOM   2860  C  CA   . PHE B 2 45  ? 39.003  1.805   16.198  1.00 51.26  ? 45  PHE B CA   1 
ATOM   2861  C  C    . PHE B 2 45  ? 39.451  1.127   17.494  1.00 42.33  ? 45  PHE B C    1 
ATOM   2862  O  O    . PHE B 2 45  ? 39.830  1.839   18.428  1.00 36.72  ? 45  PHE B O    1 
ATOM   2863  C  CB   . PHE B 2 45  ? 40.201  2.529   15.585  1.00 45.14  ? 45  PHE B CB   1 
ATOM   2864  C  CG   . PHE B 2 45  ? 41.410  1.653   15.388  1.00 41.89  ? 45  PHE B CG   1 
ATOM   2865  C  CD1  . PHE B 2 45  ? 41.409  0.648   14.436  1.00 44.96  ? 45  PHE B CD1  1 
ATOM   2866  C  CD2  . PHE B 2 45  ? 42.541  1.813   16.171  1.00 41.97  ? 45  PHE B CD2  1 
ATOM   2867  C  CE1  . PHE B 2 45  ? 42.515  -0.165  14.260  1.00 42.44  ? 45  PHE B CE1  1 
ATOM   2868  C  CE2  . PHE B 2 45  ? 43.645  0.995   15.999  1.00 43.31  ? 45  PHE B CE2  1 
ATOM   2869  C  CZ   . PHE B 2 45  ? 43.632  0.010   15.040  1.00 47.69  ? 45  PHE B CZ   1 
ATOM   2870  N  N    . ALA B 2 46  ? 39.431  -0.202  17.516  1.00 43.21  ? 46  ALA B N    1 
ATOM   2871  C  CA   . ALA B 2 46  ? 39.849  -0.997  18.693  1.00 49.08  ? 46  ALA B CA   1 
ATOM   2872  C  C    . ALA B 2 46  ? 39.270  -0.425  19.986  1.00 49.09  ? 46  ALA B C    1 
ATOM   2873  O  O    . ALA B 2 46  ? 40.013  -0.298  20.971  1.00 48.65  ? 46  ALA B O    1 
ATOM   2874  C  CB   . ALA B 2 46  ? 41.349  -1.128  18.723  1.00 45.85  ? 46  ALA B CB   1 
ATOM   2875  N  N    . GLY B 2 47  ? 37.997  -0.054  19.978  1.00 48.13  ? 47  GLY B N    1 
ATOM   2876  C  CA   . GLY B 2 47  ? 37.341  0.418   21.208  1.00 48.39  ? 47  GLY B CA   1 
ATOM   2877  C  C    . GLY B 2 47  ? 37.581  1.871   21.525  1.00 48.93  ? 47  GLY B C    1 
ATOM   2878  O  O    . GLY B 2 47  ? 37.022  2.347   22.515  1.00 53.50  ? 47  GLY B O    1 
ATOM   2879  N  N    . LYS B 2 48  ? 38.403  2.545   20.736  1.00 46.46  ? 48  LYS B N    1 
ATOM   2880  C  CA   . LYS B 2 48  ? 38.587  3.966   20.951  1.00 46.63  ? 48  LYS B CA   1 
ATOM   2881  C  C    . LYS B 2 48  ? 37.827  4.738   19.883  1.00 49.04  ? 48  LYS B C    1 
ATOM   2882  O  O    . LYS B 2 48  ? 37.792  4.340   18.715  1.00 49.97  ? 48  LYS B O    1 
ATOM   2883  C  CB   . LYS B 2 48  ? 40.077  4.331   20.941  1.00 49.62  ? 48  LYS B CB   1 
ATOM   2884  N  N    . GLN B 2 49  ? 37.191  5.825   20.291  1.00 48.59  ? 49  GLN B N    1 
ATOM   2885  C  CA   . GLN B 2 49  ? 36.717  6.814   19.331  1.00 50.15  ? 49  GLN B CA   1 
ATOM   2886  C  C    . GLN B 2 49  ? 37.883  7.743   19.008  1.00 48.45  ? 49  GLN B C    1 
ATOM   2887  O  O    . GLN B 2 49  ? 38.451  8.344   19.923  1.00 53.93  ? 49  GLN B O    1 
ATOM   2888  C  CB   . GLN B 2 49  ? 35.534  7.597   19.904  1.00 44.46  ? 49  GLN B CB   1 
ATOM   2889  C  CG   . GLN B 2 49  ? 34.927  8.599   18.930  1.00 48.55  ? 49  GLN B CG   1 
ATOM   2890  C  CD   . GLN B 2 49  ? 33.619  9.213   19.455  1.00 57.36  ? 49  GLN B CD   1 
ATOM   2891  O  OE1  . GLN B 2 49  ? 32.577  8.522   19.587  1.00 49.93  ? 49  GLN B OE1  1 
ATOM   2892  N  NE2  . GLN B 2 49  ? 33.671  10.515  19.768  1.00 45.04  ? 49  GLN B NE2  1 
ATOM   2893  N  N    . LEU B 2 50  ? 38.272  7.835   17.733  1.00 45.82  ? 50  LEU B N    1 
ATOM   2894  C  CA   . LEU B 2 50  ? 39.410  8.675   17.375  1.00 46.37  ? 50  LEU B CA   1 
ATOM   2895  C  C    . LEU B 2 50  ? 39.093  10.146  17.629  1.00 50.04  ? 50  LEU B C    1 
ATOM   2896  O  O    . LEU B 2 50  ? 37.945  10.579  17.544  1.00 50.68  ? 50  LEU B O    1 
ATOM   2897  C  CB   . LEU B 2 50  ? 39.794  8.468   15.917  1.00 46.25  ? 50  LEU B CB   1 
ATOM   2898  C  CG   . LEU B 2 50  ? 39.967  7.002   15.514  1.00 48.51  ? 50  LEU B CG   1 
ATOM   2899  C  CD1  . LEU B 2 50  ? 40.331  6.924   14.049  1.00 41.84  ? 50  LEU B CD1  1 
ATOM   2900  C  CD2  . LEU B 2 50  ? 41.014  6.279   16.384  1.00 46.54  ? 50  LEU B CD2  1 
ATOM   2901  N  N    . GLU B 2 51  ? 40.120  10.916  17.975  1.00 56.50  ? 51  GLU B N    1 
ATOM   2902  C  CA   . GLU B 2 51  ? 39.937  12.281  18.463  1.00 60.96  ? 51  GLU B CA   1 
ATOM   2903  C  C    . GLU B 2 51  ? 40.465  13.292  17.461  1.00 55.91  ? 51  GLU B C    1 
ATOM   2904  O  O    . GLU B 2 51  ? 41.614  13.189  17.015  1.00 53.79  ? 51  GLU B O    1 
ATOM   2905  C  CB   . GLU B 2 51  ? 40.658  12.498  19.793  1.00 60.15  ? 51  GLU B CB   1 
ATOM   2906  C  CG   . GLU B 2 51  ? 39.884  12.112  21.018  1.00 61.82  ? 51  GLU B CG   1 
ATOM   2907  C  CD   . GLU B 2 51  ? 40.732  12.262  22.264  1.00 72.73  ? 51  GLU B CD   1 
ATOM   2908  O  OE1  . GLU B 2 51  ? 41.077  11.230  22.881  1.00 66.71  ? 51  GLU B OE1  1 
ATOM   2909  O  OE2  . GLU B 2 51  ? 41.072  13.419  22.604  1.00 76.63  ? 51  GLU B OE2  1 
ATOM   2910  N  N    . ASP B 2 52  ? 39.636  14.277  17.131  1.00 56.34  ? 52  ASP B N    1 
ATOM   2911  C  CA   . ASP B 2 52  ? 40.134  15.425  16.388  1.00 60.43  ? 52  ASP B CA   1 
ATOM   2912  C  C    . ASP B 2 52  ? 41.390  15.959  17.074  1.00 62.56  ? 52  ASP B C    1 
ATOM   2913  O  O    . ASP B 2 52  ? 41.402  16.159  18.293  1.00 63.20  ? 52  ASP B O    1 
ATOM   2914  C  CB   . ASP B 2 52  ? 39.049  16.502  16.300  1.00 56.21  ? 52  ASP B CB   1 
ATOM   2915  C  CG   . ASP B 2 52  ? 37.926  16.129  15.324  1.00 61.67  ? 52  ASP B CG   1 
ATOM   2916  O  OD1  . ASP B 2 52  ? 38.039  15.076  14.642  1.00 58.57  ? 52  ASP B OD1  1 
ATOM   2917  O  OD2  . ASP B 2 52  ? 36.939  16.891  15.234  1.00 58.27  ? 52  ASP B OD2  1 
ATOM   2918  N  N    . GLY B 2 53  ? 42.471  16.127  16.302  1.00 54.20  ? 53  GLY B N    1 
ATOM   2919  C  CA   . GLY B 2 53  ? 43.751  16.550  16.838  1.00 53.80  ? 53  GLY B CA   1 
ATOM   2920  C  C    . GLY B 2 53  ? 44.790  15.442  16.962  1.00 59.30  ? 53  GLY B C    1 
ATOM   2921  O  O    . GLY B 2 53  ? 45.991  15.711  16.828  1.00 60.04  ? 53  GLY B O    1 
ATOM   2922  N  N    . ARG B 2 54  ? 44.372  14.205  17.205  1.00 54.20  ? 54  ARG B N    1 
ATOM   2923  C  CA   . ARG B 2 54  ? 45.374  13.155  17.195  1.00 55.14  ? 54  ARG B CA   1 
ATOM   2924  C  C    . ARG B 2 54  ? 45.671  12.746  15.750  1.00 53.64  ? 54  ARG B C    1 
ATOM   2925  O  O    . ARG B 2 54  ? 45.042  13.213  14.799  1.00 52.70  ? 54  ARG B O    1 
ATOM   2926  C  CB   . ARG B 2 54  ? 44.923  11.971  18.055  1.00 45.67  ? 54  ARG B CB   1 
ATOM   2927  N  N    . THR B 2 55  ? 46.654  11.868  15.598  1.00 53.49  ? 55  THR B N    1 
ATOM   2928  C  CA   . THR B 2 55  ? 47.013  11.365  14.252  1.00 52.28  ? 55  THR B CA   1 
ATOM   2929  C  C    . THR B 2 55  ? 46.734  9.862   14.179  1.00 49.27  ? 55  THR B C    1 
ATOM   2930  O  O    . THR B 2 55  ? 46.493  9.261   15.217  1.00 52.01  ? 55  THR B O    1 
ATOM   2931  C  CB   . THR B 2 55  ? 48.450  11.765  13.895  1.00 55.95  ? 55  THR B CB   1 
ATOM   2932  O  OG1  . THR B 2 55  ? 48.640  11.519  12.506  1.00 65.76  ? 55  THR B OG1  1 
ATOM   2933  C  CG2  . THR B 2 55  ? 49.518  11.027  14.663  1.00 49.43  ? 55  THR B CG2  1 
ATOM   2934  N  N    . LEU B 2 56  ? 46.724  9.299   12.978  1.00 49.12  ? 56  LEU B N    1 
ATOM   2935  C  CA   . LEU B 2 56  ? 46.495  7.847   12.798  1.00 50.40  ? 56  LEU B CA   1 
ATOM   2936  C  C    . LEU B 2 56  ? 47.662  7.078   13.414  1.00 54.04  ? 56  LEU B C    1 
ATOM   2937  O  O    . LEU B 2 56  ? 47.423  6.003   13.965  1.00 56.83  ? 56  LEU B O    1 
ATOM   2938  C  CB   . LEU B 2 56  ? 46.401  7.558   11.302  1.00 51.29  ? 56  LEU B CB   1 
ATOM   2939  C  CG   . LEU B 2 56  ? 45.179  8.092   10.568  1.00 48.10  ? 56  LEU B CG   1 
ATOM   2940  C  CD1  . LEU B 2 56  ? 45.265  7.716   9.102   1.00 50.20  ? 56  LEU B CD1  1 
ATOM   2941  C  CD2  . LEU B 2 56  ? 43.904  7.543   11.176  1.00 48.99  ? 56  LEU B CD2  1 
ATOM   2942  N  N    . SER B 2 57  ? 48.875  7.616   13.315  1.00 52.59  ? 57  SER B N    1 
ATOM   2943  C  CA   . SER B 2 57  ? 50.067  6.987   13.934  1.00 58.74  ? 57  SER B CA   1 
ATOM   2944  C  C    . SER B 2 57  ? 49.880  6.892   15.448  1.00 55.63  ? 57  SER B C    1 
ATOM   2945  O  O    . SER B 2 57  ? 50.355  5.914   16.031  1.00 57.25  ? 57  SER B O    1 
ATOM   2946  C  CB   . SER B 2 57  ? 51.313  7.749   13.564  1.00 52.96  ? 57  SER B CB   1 
ATOM   2947  O  OG   . SER B 2 57  ? 51.795  8.547   14.634  1.00 55.55  ? 57  SER B OG   1 
ATOM   2948  N  N    . ASP B 2 58  ? 49.231  7.886   16.041  1.00 47.43  ? 58  ASP B N    1 
ATOM   2949  C  CA   . ASP B 2 58  ? 48.993  7.897   17.500  1.00 53.87  ? 58  ASP B CA   1 
ATOM   2950  C  C    . ASP B 2 58  ? 48.204  6.651   17.882  1.00 56.14  ? 58  ASP B C    1 
ATOM   2951  O  O    . ASP B 2 58  ? 48.208  6.308   19.066  1.00 56.87  ? 58  ASP B O    1 
ATOM   2952  C  CB   . ASP B 2 58  ? 48.283  9.179   17.929  1.00 52.99  ? 58  ASP B CB   1 
ATOM   2953  C  CG   . ASP B 2 58  ? 49.185  10.394  18.012  1.00 58.05  ? 58  ASP B CG   1 
ATOM   2954  O  OD1  . ASP B 2 58  ? 50.412  10.227  17.897  1.00 67.60  ? 58  ASP B OD1  1 
ATOM   2955  O  OD2  . ASP B 2 58  ? 48.648  11.499  18.178  1.00 61.62  ? 58  ASP B OD2  1 
ATOM   2956  N  N    . TYR B 2 59  ? 47.569  6.002   16.908  1.00 52.18  ? 59  TYR B N    1 
ATOM   2957  C  CA   . TYR B 2 59  ? 46.748  4.849   17.252  1.00 51.51  ? 59  TYR B CA   1 
ATOM   2958  C  C    . TYR B 2 59  ? 47.319  3.549   16.721  1.00 52.61  ? 59  TYR B C    1 
ATOM   2959  O  O    . TYR B 2 59  ? 46.638  2.527   16.783  1.00 55.39  ? 59  TYR B O    1 
ATOM   2960  C  CB   . TYR B 2 59  ? 45.319  5.034   16.724  1.00 50.69  ? 59  TYR B CB   1 
ATOM   2961  C  CG   . TYR B 2 59  ? 44.555  6.151   17.401  1.00 52.45  ? 59  TYR B CG   1 
ATOM   2962  C  CD1  . TYR B 2 59  ? 44.596  7.439   16.908  1.00 51.13  ? 59  TYR B CD1  1 
ATOM   2963  C  CD2  . TYR B 2 59  ? 43.803  5.914   18.545  1.00 49.59  ? 59  TYR B CD2  1 
ATOM   2964  C  CE1  . TYR B 2 59  ? 43.893  8.467   17.523  1.00 48.71  ? 59  TYR B CE1  1 
ATOM   2965  C  CE2  . TYR B 2 59  ? 43.108  6.929   19.161  1.00 51.08  ? 59  TYR B CE2  1 
ATOM   2966  C  CZ   . TYR B 2 59  ? 43.167  8.210   18.648  1.00 52.00  ? 59  TYR B CZ   1 
ATOM   2967  O  OH   . TYR B 2 59  ? 42.476  9.232   19.259  1.00 53.25  ? 59  TYR B OH   1 
ATOM   2968  N  N    . ASN B 2 60  ? 48.543  3.554   16.187  1.00 54.91  ? 60  ASN B N    1 
ATOM   2969  C  CA   . ASN B 2 60  ? 49.072  2.378   15.482  1.00 56.13  ? 60  ASN B CA   1 
ATOM   2970  C  C    . ASN B 2 60  ? 48.086  1.902   14.408  1.00 54.34  ? 60  ASN B C    1 
ATOM   2971  O  O    . ASN B 2 60  ? 47.959  0.707   14.132  1.00 55.53  ? 60  ASN B O    1 
ATOM   2972  C  CB   . ASN B 2 60  ? 49.413  1.252   16.468  1.00 61.50  ? 60  ASN B CB   1 
ATOM   2973  C  CG   . ASN B 2 60  ? 50.281  0.141   15.845  1.00 64.69  ? 60  ASN B CG   1 
ATOM   2974  O  OD1  . ASN B 2 60  ? 51.330  0.405   15.262  1.00 68.18  ? 60  ASN B OD1  1 
ATOM   2975  N  ND2  . ASN B 2 60  ? 49.838  -1.107  15.985  1.00 64.84  ? 60  ASN B ND2  1 
ATOM   2976  N  N    . ILE B 2 61  ? 47.433  2.870   13.766  1.00 56.61  ? 61  ILE B N    1 
ATOM   2977  C  CA   . ILE B 2 61  ? 46.562  2.536   12.607  1.00 55.09  ? 61  ILE B CA   1 
ATOM   2978  C  C    . ILE B 2 61  ? 47.505  2.428   11.418  1.00 53.59  ? 61  ILE B C    1 
ATOM   2979  O  O    . ILE B 2 61  ? 48.206  3.402   11.124  1.00 49.32  ? 61  ILE B O    1 
ATOM   2980  C  CB   . ILE B 2 61  ? 45.449  3.578   12.380  1.00 52.53  ? 61  ILE B CB   1 
ATOM   2981  C  CG1  . ILE B 2 61  ? 44.363  3.475   13.449  1.00 50.94  ? 61  ILE B CG1  1 
ATOM   2982  C  CG2  . ILE B 2 61  ? 44.854  3.470   10.987  1.00 41.31  ? 61  ILE B CG2  1 
ATOM   2983  C  CD1  . ILE B 2 61  ? 43.482  4.689   13.546  1.00 47.74  ? 61  ILE B CD1  1 
ATOM   2984  N  N    . GLN B 2 62  ? 47.567  1.242   10.831  1.00 56.74  ? 62  GLN B N    1 
ATOM   2985  C  CA   . GLN B 2 62  ? 48.481  1.005   9.698   1.00 56.69  ? 62  GLN B CA   1 
ATOM   2986  C  C    . GLN B 2 62  ? 47.659  0.590   8.484   1.00 58.34  ? 62  GLN B C    1 
ATOM   2987  O  O    . GLN B 2 62  ? 46.450  0.835   8.463   1.00 53.62  ? 62  GLN B O    1 
ATOM   2988  C  CB   . GLN B 2 62  ? 49.493  -0.091  10.039  1.00 57.91  ? 62  GLN B CB   1 
ATOM   2989  C  CG   . GLN B 2 62  ? 49.556  -0.485  11.503  1.00 58.01  ? 62  GLN B CG   1 
ATOM   2990  C  CD   . GLN B 2 62  ? 50.820  -1.246  11.805  1.00 67.54  ? 62  GLN B CD   1 
ATOM   2991  O  OE1  . GLN B 2 62  ? 50.883  -2.462  11.658  1.00 81.36  ? 62  GLN B OE1  1 
ATOM   2992  N  NE2  . GLN B 2 62  ? 51.846  -0.525  12.224  1.00 72.45  ? 62  GLN B NE2  1 
ATOM   2993  N  N    . LYS B 2 63  ? 48.314  -0.043  7.525   1.00 48.60  ? 63  LYS B N    1 
ATOM   2994  C  CA   . LYS B 2 63  ? 47.626  -0.493  6.301   1.00 54.10  ? 63  LYS B CA   1 
ATOM   2995  C  C    . LYS B 2 63  ? 46.695  -1.654  6.630   1.00 50.61  ? 63  LYS B C    1 
ATOM   2996  O  O    . LYS B 2 63  ? 47.096  -2.492  7.436   1.00 47.87  ? 63  LYS B O    1 
ATOM   2997  C  CB   . LYS B 2 63  ? 48.685  -0.879  5.265   1.00 55.62  ? 63  LYS B CB   1 
ATOM   2998  C  CG   . LYS B 2 63  ? 48.193  -1.144  3.852   1.00 58.00  ? 63  LYS B CG   1 
ATOM   2999  C  CD   . LYS B 2 63  ? 48.912  -2.302  3.205   1.00 56.81  ? 63  LYS B CD   1 
ATOM   3000  C  CE   . LYS B 2 63  ? 48.540  -2.504  1.753   1.00 54.57  ? 63  LYS B CE   1 
ATOM   3001  N  NZ   . LYS B 2 63  ? 47.079  -2.663  1.573   1.00 56.45  ? 63  LYS B NZ   1 
ATOM   3002  N  N    . GLU B 2 64  ? 45.505  -1.672  6.035   1.00 52.40  ? 64  GLU B N    1 
ATOM   3003  C  CA   . GLU B 2 64  ? 44.501  -2.766  6.197   1.00 52.53  ? 64  GLU B CA   1 
ATOM   3004  C  C    . GLU B 2 64  ? 43.798  -2.651  7.544   1.00 51.20  ? 64  GLU B C    1 
ATOM   3005  O  O    . GLU B 2 64  ? 43.001  -3.531  7.860   1.00 47.53  ? 64  GLU B O    1 
ATOM   3006  C  CB   . GLU B 2 64  ? 45.098  -4.130  5.877   1.00 48.27  ? 64  GLU B CB   1 
ATOM   3007  C  CG   . GLU B 2 64  ? 45.641  -4.177  4.471   1.00 52.85  ? 64  GLU B CG   1 
ATOM   3008  C  CD   . GLU B 2 64  ? 46.196  -5.533  4.119   1.00 53.79  ? 64  GLU B CD   1 
ATOM   3009  O  OE1  . GLU B 2 64  ? 47.287  -5.593  3.536   1.00 62.05  ? 64  GLU B OE1  1 
ATOM   3010  O  OE2  . GLU B 2 64  ? 45.524  -6.515  4.439   1.00 56.65  ? 64  GLU B OE2  1 
ATOM   3011  N  N    . SER B 2 65  ? 44.054  -1.569  8.263   1.00 44.46  ? 65  SER B N    1 
ATOM   3012  C  CA   . SER B 2 65  ? 43.304  -1.324  9.507   1.00 45.48  ? 65  SER B CA   1 
ATOM   3013  C  C    . SER B 2 65  ? 41.881  -0.899  9.142   1.00 47.72  ? 65  SER B C    1 
ATOM   3014  O  O    . SER B 2 65  ? 41.712  -0.211  8.144   1.00 48.95  ? 65  SER B O    1 
ATOM   3015  C  CB   . SER B 2 65  ? 44.003  -0.327  10.374  1.00 45.16  ? 65  SER B CB   1 
ATOM   3016  O  OG   . SER B 2 65  ? 44.995  -0.954  11.170  1.00 61.10  ? 65  SER B OG   1 
ATOM   3017  N  N    . THR B 2 66  ? 40.899  -1.321  9.918   1.00 42.77  ? 66  THR B N    1 
ATOM   3018  C  CA   . THR B 2 66  ? 39.493  -1.023  9.678   1.00 47.07  ? 66  THR B CA   1 
ATOM   3019  C  C    . THR B 2 66  ? 39.007  -0.015  10.709  1.00 47.51  ? 66  THR B C    1 
ATOM   3020  O  O    . THR B 2 66  ? 39.191  -0.217  11.914  1.00 49.06  ? 66  THR B O    1 
ATOM   3021  C  CB   . THR B 2 66  ? 38.651  -2.304  9.740   1.00 51.63  ? 66  THR B CB   1 
ATOM   3022  O  OG1  . THR B 2 66  ? 39.122  -3.233  8.743   1.00 50.93  ? 66  THR B OG1  1 
ATOM   3023  C  CG2  . THR B 2 66  ? 37.160  -2.004  9.501   1.00 46.60  ? 66  THR B CG2  1 
ATOM   3024  N  N    . LEU B 2 67  ? 38.406  1.071   10.246  1.00 46.42  ? 67  LEU B N    1 
ATOM   3025  C  CA   . LEU B 2 67  ? 37.735  2.009   11.136  1.00 43.10  ? 67  LEU B CA   1 
ATOM   3026  C  C    . LEU B 2 67  ? 36.232  1.846   10.967  1.00 45.63  ? 67  LEU B C    1 
ATOM   3027  O  O    . LEU B 2 67  ? 35.760  1.459   9.894   1.00 51.74  ? 67  LEU B O    1 
ATOM   3028  C  CB   . LEU B 2 67  ? 38.136  3.445   10.836  1.00 41.84  ? 67  LEU B CB   1 
ATOM   3029  C  CG   . LEU B 2 67  ? 39.625  3.670   10.655  1.00 44.76  ? 67  LEU B CG   1 
ATOM   3030  C  CD1  . LEU B 2 67  ? 39.869  5.145   10.466  1.00 48.05  ? 67  LEU B CD1  1 
ATOM   3031  C  CD2  . LEU B 2 67  ? 40.390  3.163   11.867  1.00 49.60  ? 67  LEU B CD2  1 
ATOM   3032  N  N    . HIS B 2 68  ? 35.470  2.115   12.025  1.00 43.24  ? 68  HIS B N    1 
ATOM   3033  C  CA   . HIS B 2 68  ? 34.023  1.911   11.981  1.00 46.76  ? 68  HIS B CA   1 
ATOM   3034  C  C    . HIS B 2 68  ? 33.356  3.255   12.170  1.00 43.77  ? 68  HIS B C    1 
ATOM   3035  O  O    . HIS B 2 68  ? 33.574  3.922   13.195  1.00 46.30  ? 68  HIS B O    1 
ATOM   3036  C  CB   . HIS B 2 68  ? 33.532  0.900   13.032  1.00 41.31  ? 68  HIS B CB   1 
ATOM   3037  C  CG   . HIS B 2 68  ? 34.246  -0.412  12.963  1.00 46.06  ? 68  HIS B CG   1 
ATOM   3038  N  ND1  . HIS B 2 68  ? 33.808  -1.458  12.176  1.00 45.24  ? 68  HIS B ND1  1 
ATOM   3039  C  CD2  . HIS B 2 68  ? 35.398  -0.826  13.541  1.00 41.10  ? 68  HIS B CD2  1 
ATOM   3040  C  CE1  . HIS B 2 68  ? 34.651  -2.465  12.292  1.00 46.22  ? 68  HIS B CE1  1 
ATOM   3041  N  NE2  . HIS B 2 68  ? 35.622  -2.107  13.114  1.00 49.15  ? 68  HIS B NE2  1 
ATOM   3042  N  N    . LEU B 2 69  ? 32.563  3.645   11.173  1.00 44.47  ? 69  LEU B N    1 
ATOM   3043  C  CA   . LEU B 2 69  ? 31.918  4.951   11.122  1.00 50.93  ? 69  LEU B CA   1 
ATOM   3044  C  C    . LEU B 2 69  ? 30.523  4.872   11.746  1.00 47.07  ? 69  LEU B C    1 
ATOM   3045  O  O    . LEU B 2 69  ? 29.755  3.948   11.460  1.00 47.80  ? 69  LEU B O    1 
ATOM   3046  C  CB   . LEU B 2 69  ? 31.843  5.435   9.669   1.00 43.92  ? 69  LEU B CB   1 
ATOM   3047  C  CG   . LEU B 2 69  ? 31.191  6.795   9.400   1.00 46.88  ? 69  LEU B CG   1 
ATOM   3048  C  CD1  . LEU B 2 69  ? 32.007  7.916   10.004  1.00 41.84  ? 69  LEU B CD1  1 
ATOM   3049  C  CD2  . LEU B 2 69  ? 31.012  7.026   7.905   1.00 49.92  ? 69  LEU B CD2  1 
ATOM   3050  N  N    . VAL B 2 70  ? 30.197  5.837   12.604  1.00 44.30  ? 70  VAL B N    1 
ATOM   3051  C  CA   . VAL B 2 70  ? 28.870  5.916   13.202  1.00 51.29  ? 70  VAL B CA   1 
ATOM   3052  C  C    . VAL B 2 70  ? 28.453  7.375   13.334  1.00 49.48  ? 70  VAL B C    1 
ATOM   3053  O  O    . VAL B 2 70  ? 29.279  8.289   13.295  1.00 47.00  ? 70  VAL B O    1 
ATOM   3054  C  CB   . VAL B 2 70  ? 28.793  5.231   14.591  1.00 52.77  ? 70  VAL B CB   1 
ATOM   3055  C  CG1  . VAL B 2 70  ? 29.020  3.732   14.483  1.00 48.10  ? 70  VAL B CG1  1 
ATOM   3056  C  CG2  . VAL B 2 70  ? 29.778  5.863   15.540  1.00 49.53  ? 70  VAL B CG2  1 
ATOM   3057  N  N    . LEU B 2 71  ? 27.146  7.576   13.515  1.00 53.38  ? 71  LEU B N    1 
ATOM   3058  C  CA   . LEU B 2 71  ? 26.551  8.882   13.758  1.00 53.32  ? 71  LEU B CA   1 
ATOM   3059  C  C    . LEU B 2 71  ? 26.203  9.006   15.244  1.00 47.87  ? 71  LEU B C    1 
ATOM   3060  O  O    . LEU B 2 71  ? 26.764  8.288   16.081  1.00 47.53  ? 71  LEU B O    1 
ATOM   3061  C  CB   . LEU B 2 71  ? 25.342  9.073   12.834  1.00 47.20  ? 71  LEU B CB   1 
ATOM   3062  C  CG   . LEU B 2 71  ? 25.712  8.978   11.353  1.00 52.70  ? 71  LEU B CG   1 
ATOM   3063  C  CD1  . LEU B 2 71  ? 24.563  9.425   10.481  1.00 53.36  ? 71  LEU B CD1  1 
ATOM   3064  C  CD2  . LEU B 2 71  ? 26.975  9.765   11.032  1.00 48.36  ? 71  LEU B CD2  1 
ATOM   3065  N  N    . ARG B 2 72  ? 25.269  9.899   15.535  1.00 44.82  ? 72  ARG B N    1 
ATOM   3066  C  CA   . ARG B 2 72  ? 24.923  10.150  16.943  1.00 47.38  ? 72  ARG B CA   1 
ATOM   3067  C  C    . ARG B 2 72  ? 23.419  10.099  17.152  1.00 48.70  ? 72  ARG B C    1 
ATOM   3068  O  O    . ARG B 2 72  ? 22.703  10.761  16.399  1.00 57.77  ? 72  ARG B O    1 
ATOM   3069  C  CB   . ARG B 2 72  ? 25.404  11.543  17.348  1.00 44.31  ? 72  ARG B CB   1 
ATOM   3070  C  CG   . ARG B 2 72  ? 26.650  11.583  18.212  1.00 44.18  ? 72  ARG B CG   1 
ATOM   3071  C  CD   . ARG B 2 72  ? 27.098  13.023  18.324  1.00 50.55  ? 72  ARG B CD   1 
ATOM   3072  N  NE   . ARG B 2 72  ? 28.527  13.188  18.528  1.00 48.81  ? 72  ARG B NE   1 
ATOM   3073  C  CZ   . ARG B 2 72  ? 29.373  13.656  17.622  1.00 49.44  ? 72  ARG B CZ   1 
ATOM   3074  N  NH1  . ARG B 2 72  ? 28.939  14.006  16.424  1.00 45.91  ? 72  ARG B NH1  1 
ATOM   3075  N  NH2  . ARG B 2 72  ? 30.655  13.763  17.914  1.00 40.53  ? 72  ARG B NH2  1 
ATOM   3076  N  N    . LEU B 2 73  ? 22.966  9.309   18.113  1.00 46.10  ? 73  LEU B N    1 
ATOM   3077  C  CA   . LEU B 2 73  ? 21.546  9.345   18.513  1.00 52.35  ? 73  LEU B CA   1 
ATOM   3078  C  C    . LEU B 2 73  ? 21.574  10.067  19.860  1.00 53.79  ? 73  LEU B C    1 
ATOM   3079  O  O    . LEU B 2 73  ? 21.921  9.436   20.844  1.00 54.59  ? 73  LEU B O    1 
ATOM   3080  C  CB   . LEU B 2 73  ? 21.002  7.918   18.603  1.00 53.38  ? 73  LEU B CB   1 
ATOM   3081  C  CG   . LEU B 2 73  ? 19.865  7.571   17.647  1.00 47.98  ? 73  LEU B CG   1 
ATOM   3082  C  CD1  . LEU B 2 73  ? 20.149  8.080   16.245  1.00 54.52  ? 73  LEU B CD1  1 
ATOM   3083  C  CD2  . LEU B 2 73  ? 19.632  6.074   17.625  1.00 54.83  ? 73  LEU B CD2  1 
ATOM   3084  N  N    . ARG B 2 74  ? 21.289  11.368  19.881  1.00 56.57  ? 74  ARG B N    1 
ATOM   3085  C  CA   . ARG B 2 74  ? 21.413  12.178  21.124  1.00 59.92  ? 74  ARG B CA   1 
ATOM   3086  C  C    . ARG B 2 74  ? 20.188  12.052  22.033  1.00 62.62  ? 74  ARG B C    1 
ATOM   3087  O  O    . ARG B 2 74  ? 19.104  11.755  21.526  1.00 60.81  ? 74  ARG B O    1 
ATOM   3088  C  CB   . ARG B 2 74  ? 21.695  13.638  20.761  1.00 62.91  ? 74  ARG B CB   1 
ATOM   3089  C  CG   . ARG B 2 74  ? 22.917  13.831  19.878  1.00 60.84  ? 74  ARG B CG   1 
ATOM   3090  C  CD   . ARG B 2 74  ? 23.350  15.279  19.813  1.00 57.12  ? 74  ARG B CD   1 
ATOM   3091  N  NE   . ARG B 2 74  ? 24.608  15.480  20.514  1.00 63.52  ? 74  ARG B NE   1 
ATOM   3092  C  CZ   . ARG B 2 74  ? 25.708  15.977  19.964  1.00 60.83  ? 74  ARG B CZ   1 
ATOM   3093  N  NH1  . ARG B 2 74  ? 25.713  16.332  18.691  1.00 63.05  ? 74  ARG B NH1  1 
ATOM   3094  N  NH2  . ARG B 2 74  ? 26.803  16.115  20.686  1.00 58.79  ? 74  ARG B NH2  1 
ATOM   3095  N  N    . GLY B 2 75  ? 20.360  12.285  23.333  1.00 64.21  ? 75  GLY B N    1 
ATOM   3096  C  CA   . GLY B 2 75  ? 19.249  12.172  24.295  1.00 58.74  ? 75  GLY B CA   1 
ATOM   3097  C  C    . GLY B 2 75  ? 19.642  12.619  25.688  1.00 63.04  ? 75  GLY B C    1 
ATOM   3098  O  O    . GLY B 2 75  ? 18.877  13.402  26.265  1.00 63.43  ? 75  GLY B O    1 
ATOM   3099  N  N    . THR C 1 4   ? 92.150  -23.741 40.128  1.00 71.08  ? 211 THR C N    1 
ATOM   3100  C  CA   . THR C 1 4   ? 91.330  -23.991 38.938  1.00 74.19  ? 211 THR C CA   1 
ATOM   3101  C  C    . THR C 1 4   ? 92.208  -24.107 37.691  1.00 76.27  ? 211 THR C C    1 
ATOM   3102  O  O    . THR C 1 4   ? 92.234  -25.155 37.029  1.00 81.49  ? 211 THR C O    1 
ATOM   3103  C  CB   . THR C 1 4   ? 90.261  -22.875 38.709  1.00 71.42  ? 211 THR C CB   1 
ATOM   3104  O  OG1  . THR C 1 4   ? 90.862  -21.720 38.100  1.00 67.29  ? 211 THR C OG1  1 
ATOM   3105  C  CG2  . THR C 1 4   ? 89.596  -22.471 40.026  1.00 70.96  ? 211 THR C CG2  1 
ATOM   3106  N  N    . GLY C 1 5   ? 92.932  -23.031 37.385  1.00 72.09  ? 212 GLY C N    1 
ATOM   3107  C  CA   . GLY C 1 5   ? 93.842  -22.984 36.253  1.00 64.45  ? 212 GLY C CA   1 
ATOM   3108  C  C    . GLY C 1 5   ? 93.444  -21.992 35.185  1.00 68.00  ? 212 GLY C C    1 
ATOM   3109  O  O    . GLY C 1 5   ? 94.184  -21.834 34.199  1.00 64.82  ? 212 GLY C O    1 
ATOM   3110  N  N    . TYR C 1 6   ? 92.316  -21.306 35.334  1.00 65.40  ? 213 TYR C N    1 
ATOM   3111  C  CA   . TYR C 1 6   ? 91.788  -20.419 34.306  1.00 68.04  ? 213 TYR C CA   1 
ATOM   3112  C  C    . TYR C 1 6   ? 91.631  -19.019 34.889  1.00 65.25  ? 213 TYR C C    1 
ATOM   3113  O  O    . TYR C 1 6   ? 91.755  -18.817 36.096  1.00 70.49  ? 213 TYR C O    1 
ATOM   3114  C  CB   . TYR C 1 6   ? 90.450  -20.946 33.769  1.00 61.37  ? 213 TYR C CB   1 
ATOM   3115  C  CG   . TYR C 1 6   ? 90.392  -22.446 33.557  1.00 58.33  ? 213 TYR C CG   1 
ATOM   3116  C  CD1  . TYR C 1 6   ? 91.020  -23.042 32.467  1.00 61.47  ? 213 TYR C CD1  1 
ATOM   3117  C  CD2  . TYR C 1 6   ? 89.690  -23.268 34.432  1.00 62.38  ? 213 TYR C CD2  1 
ATOM   3118  C  CE1  . TYR C 1 6   ? 90.956  -24.422 32.262  1.00 58.13  ? 213 TYR C CE1  1 
ATOM   3119  C  CE2  . TYR C 1 6   ? 89.621  -24.650 34.231  1.00 57.38  ? 213 TYR C CE2  1 
ATOM   3120  C  CZ   . TYR C 1 6   ? 90.256  -25.215 33.143  1.00 55.67  ? 213 TYR C CZ   1 
ATOM   3121  O  OH   . TYR C 1 6   ? 90.196  -26.573 32.931  1.00 61.96  ? 213 TYR C OH   1 
ATOM   3122  N  N    . VAL C 1 7   ? 91.364  -18.035 34.037  1.00 57.39  ? 214 VAL C N    1 
ATOM   3123  C  CA   . VAL C 1 7   ? 91.196  -16.666 34.504  1.00 66.25  ? 214 VAL C CA   1 
ATOM   3124  C  C    . VAL C 1 7   ? 89.829  -16.155 34.059  1.00 70.43  ? 214 VAL C C    1 
ATOM   3125  O  O    . VAL C 1 7   ? 89.164  -16.739 33.199  1.00 70.26  ? 214 VAL C O    1 
ATOM   3126  C  CB   . VAL C 1 7   ? 92.316  -15.717 34.022  1.00 70.48  ? 214 VAL C CB   1 
ATOM   3127  C  CG1  . VAL C 1 7   ? 93.692  -16.308 34.291  1.00 73.64  ? 214 VAL C CG1  1 
ATOM   3128  C  CG2  . VAL C 1 7   ? 92.154  -15.388 32.556  1.00 66.23  ? 214 VAL C CG2  1 
ATOM   3129  N  N    . GLY C 1 8   ? 89.413  -15.052 34.681  1.00 62.05  ? 215 GLY C N    1 
ATOM   3130  C  CA   . GLY C 1 8   ? 88.137  -14.439 34.407  1.00 63.22  ? 215 GLY C CA   1 
ATOM   3131  C  C    . GLY C 1 8   ? 88.241  -13.308 33.398  1.00 68.58  ? 215 GLY C C    1 
ATOM   3132  O  O    . GLY C 1 8   ? 89.284  -13.057 32.784  1.00 61.46  ? 215 GLY C O    1 
ATOM   3133  N  N    . LEU C 1 9   ? 87.109  -12.633 33.208  1.00 65.76  ? 216 LEU C N    1 
ATOM   3134  C  CA   . LEU C 1 9   ? 87.052  -11.494 32.267  1.00 66.47  ? 216 LEU C CA   1 
ATOM   3135  C  C    . LEU C 1 9   ? 86.503  -10.280 33.009  1.00 69.65  ? 216 LEU C C    1 
ATOM   3136  O  O    . LEU C 1 9   ? 85.494  -10.407 33.685  1.00 66.80  ? 216 LEU C O    1 
ATOM   3137  C  CB   . LEU C 1 9   ? 86.166  -11.863 31.077  1.00 66.87  ? 216 LEU C CB   1 
ATOM   3138  C  CG   . LEU C 1 9   ? 86.785  -12.790 30.035  1.00 62.74  ? 216 LEU C CG   1 
ATOM   3139  C  CD1  . LEU C 1 9   ? 85.713  -13.628 29.369  1.00 63.52  ? 216 LEU C CD1  1 
ATOM   3140  C  CD2  . LEU C 1 9   ? 87.546  -11.997 28.991  1.00 54.97  ? 216 LEU C CD2  1 
ATOM   3141  N  N    . LYS C 1 10  ? 87.117  -9.125  32.826  1.00 70.46  ? 217 LYS C N    1 
ATOM   3142  C  CA   . LYS C 1 10  ? 86.751  -7.912  33.541  1.00 69.13  ? 217 LYS C CA   1 
ATOM   3143  C  C    . LYS C 1 10  ? 85.373  -7.483  33.073  1.00 68.09  ? 217 LYS C C    1 
ATOM   3144  O  O    . LYS C 1 10  ? 85.151  -7.319  31.872  1.00 71.16  ? 217 LYS C O    1 
ATOM   3145  C  CB   . LYS C 1 10  ? 87.777  -6.806  33.282  1.00 68.17  ? 217 LYS C CB   1 
ATOM   3146  C  CG   . LYS C 1 10  ? 89.241  -7.153  33.596  1.00 63.54  ? 217 LYS C CG   1 
ATOM   3147  C  CD   . LYS C 1 10  ? 90.087  -5.887  33.668  1.00 62.24  ? 217 LYS C CD   1 
ATOM   3148  C  CE   . LYS C 1 10  ? 91.124  -5.809  32.558  1.00 68.19  ? 217 LYS C CE   1 
ATOM   3149  N  NZ   . LYS C 1 10  ? 91.107  -4.519  31.788  1.00 69.51  ? 217 LYS C NZ   1 
ATOM   3150  N  N    . ASN C 1 11  ? 84.501  -7.215  34.034  1.00 67.36  ? 218 ASN C N    1 
ATOM   3151  C  CA   . ASN C 1 11  ? 83.195  -6.636  33.663  1.00 71.04  ? 218 ASN C CA   1 
ATOM   3152  C  C    . ASN C 1 11  ? 83.447  -5.166  33.358  1.00 72.24  ? 218 ASN C C    1 
ATOM   3153  O  O    . ASN C 1 11  ? 83.994  -4.473  34.224  1.00 73.54  ? 218 ASN C O    1 
ATOM   3154  C  CB   . ASN C 1 11  ? 82.163  -6.789  34.774  1.00 65.02  ? 218 ASN C CB   1 
ATOM   3155  C  CG   . ASN C 1 11  ? 80.825  -6.158  34.456  1.00 69.05  ? 218 ASN C CG   1 
ATOM   3156  O  OD1  . ASN C 1 11  ? 80.409  -6.117  33.304  1.00 67.65  ? 218 ASN C OD1  1 
ATOM   3157  N  ND2  . ASN C 1 11  ? 80.145  -5.665  35.476  1.00 67.08  ? 218 ASN C ND2  1 
ATOM   3158  N  N    . GLN C 1 12  ? 83.076  -4.725  32.164  1.00 74.57  ? 219 GLN C N    1 
ATOM   3159  C  CA   . GLN C 1 12  ? 83.217  -3.296  31.807  1.00 73.35  ? 219 GLN C CA   1 
ATOM   3160  C  C    . GLN C 1 12  ? 82.122  -2.511  32.519  1.00 72.45  ? 219 GLN C C    1 
ATOM   3161  O  O    . GLN C 1 12  ? 82.371  -1.345  32.845  1.00 81.22  ? 219 GLN C O    1 
ATOM   3162  C  CB   . GLN C 1 12  ? 83.095  -3.115  30.297  1.00 66.43  ? 219 GLN C CB   1 
ATOM   3163  C  CG   . GLN C 1 12  ? 84.354  -3.454  29.515  1.00 69.27  ? 219 GLN C CG   1 
ATOM   3164  C  CD   . GLN C 1 12  ? 84.229  -3.045  28.067  1.00 69.67  ? 219 GLN C CD   1 
ATOM   3165  O  OE1  . GLN C 1 12  ? 84.015  -1.881  27.743  1.00 69.57  ? 219 GLN C OE1  1 
ATOM   3166  N  NE2  . GLN C 1 12  ? 84.349  -4.010  27.175  1.00 70.15  ? 219 GLN C NE2  1 
ATOM   3167  N  N    . GLY C 1 13  ? 80.965  -3.131  32.747  1.00 65.04  ? 220 GLY C N    1 
ATOM   3168  C  CA   . GLY C 1 13  ? 79.854  -2.460  33.441  1.00 63.40  ? 220 GLY C CA   1 
ATOM   3169  C  C    . GLY C 1 13  ? 78.628  -3.335  33.514  1.00 64.91  ? 220 GLY C C    1 
ATOM   3170  O  O    . GLY C 1 13  ? 78.041  -3.420  34.597  1.00 63.90  ? 220 GLY C O    1 
ATOM   3171  N  N    . ALA C 1 14  ? 78.269  -3.965  32.399  1.00 73.07  ? 221 ALA C N    1 
ATOM   3172  C  CA   . ALA C 1 14  ? 77.104  -4.872  32.345  1.00 70.22  ? 221 ALA C CA   1 
ATOM   3173  C  C    . ALA C 1 14  ? 77.413  -6.024  31.394  1.00 64.14  ? 221 ALA C C    1 
ATOM   3174  O  O    . ALA C 1 14  ? 76.468  -6.708  31.006  1.00 59.71  ? 221 ALA C O    1 
ATOM   3175  C  CB   . ALA C 1 14  ? 75.914  -4.098  31.874  1.00 62.73  ? 221 ALA C CB   1 
ATOM   3176  N  N    . THR C 1 15  ? 78.689  -6.251  31.092  1.00 60.85  ? 222 THR C N    1 
ATOM   3177  C  CA   . THR C 1 15  ? 79.100  -7.271  30.097  1.00 59.32  ? 222 THR C CA   1 
ATOM   3178  C  C    . THR C 1 15  ? 79.121  -8.680  30.692  1.00 59.76  ? 222 THR C C    1 
ATOM   3179  O  O    . THR C 1 15  ? 79.883  -9.493  30.178  1.00 64.51  ? 222 THR C O    1 
ATOM   3180  C  CB   . THR C 1 15  ? 80.454  -6.864  29.511  1.00 62.33  ? 222 THR C CB   1 
ATOM   3181  O  OG1  . THR C 1 15  ? 81.464  -6.923  30.518  1.00 66.77  ? 222 THR C OG1  1 
ATOM   3182  C  CG2  . THR C 1 15  ? 80.421  -5.474  28.920  1.00 62.48  ? 222 THR C CG2  1 
ATOM   3183  N  N    . CYS C 1 16  ? 78.310  -8.953  31.712  1.00 60.62  ? 223 CYS C N    1 
ATOM   3184  C  CA   . CYS C 1 16  ? 78.212  -10.323 32.273  1.00 64.06  ? 223 CYS C CA   1 
ATOM   3185  C  C    . CYS C 1 16  ? 77.858  -11.295 31.151  1.00 63.49  ? 223 CYS C C    1 
ATOM   3186  O  O    . CYS C 1 16  ? 78.419  -12.392 31.136  1.00 56.38  ? 223 CYS C O    1 
ATOM   3187  C  CB   . CYS C 1 16  ? 77.123  -10.413 33.333  1.00 59.92  ? 223 CYS C CB   1 
ATOM   3188  S  SG   . CYS C 1 16  ? 76.049  -8.964  33.433  1.00 65.81  ? 223 CYS C SG   1 
ATOM   3189  N  N    . TYR C 1 17  ? 76.955  -10.889 30.259  1.00 63.02  ? 224 TYR C N    1 
ATOM   3190  C  CA   . TYR C 1 17  ? 76.507  -11.744 29.134  1.00 60.24  ? 224 TYR C CA   1 
ATOM   3191  C  C    . TYR C 1 17  ? 77.699  -12.076 28.245  1.00 59.84  ? 224 TYR C C    1 
ATOM   3192  O  O    . TYR C 1 17  ? 77.911  -13.257 27.985  1.00 58.84  ? 224 TYR C O    1 
ATOM   3193  C  CB   . TYR C 1 17  ? 75.379  -11.047 28.367  1.00 60.09  ? 224 TYR C CB   1 
ATOM   3194  C  CG   . TYR C 1 17  ? 75.718  -9.718  27.742  1.00 61.15  ? 224 TYR C CG   1 
ATOM   3195  C  CD1  . TYR C 1 17  ? 75.674  -8.549  28.477  1.00 58.14  ? 224 TYR C CD1  1 
ATOM   3196  C  CD2  . TYR C 1 17  ? 76.079  -9.629  26.409  1.00 61.18  ? 224 TYR C CD2  1 
ATOM   3197  C  CE1  . TYR C 1 17  ? 76.000  -7.329  27.913  1.00 64.37  ? 224 TYR C CE1  1 
ATOM   3198  C  CE2  . TYR C 1 17  ? 76.431  -8.422  25.837  1.00 60.58  ? 224 TYR C CE2  1 
ATOM   3199  C  CZ   . TYR C 1 17  ? 76.377  -7.263  26.587  1.00 68.63  ? 224 TYR C CZ   1 
ATOM   3200  O  OH   . TYR C 1 17  ? 76.691  -6.062  26.027  1.00 66.61  ? 224 TYR C OH   1 
ATOM   3201  N  N    . MET C 1 18  ? 78.440  -11.060 27.812  1.00 56.96  ? 225 MET C N    1 
ATOM   3202  C  CA   . MET C 1 18  ? 79.589  -11.272 26.913  1.00 54.09  ? 225 MET C CA   1 
ATOM   3203  C  C    . MET C 1 18  ? 80.570  -12.201 27.606  1.00 60.54  ? 225 MET C C    1 
ATOM   3204  O  O    . MET C 1 18  ? 80.957  -13.172 26.995  1.00 60.36  ? 225 MET C O    1 
ATOM   3205  C  CB   . MET C 1 18  ? 80.272  -9.948  26.579  1.00 61.30  ? 225 MET C CB   1 
ATOM   3206  C  CG   . MET C 1 18  ? 80.790  -9.892  25.161  1.00 67.65  ? 225 MET C CG   1 
ATOM   3207  S  SD   . MET C 1 18  ? 81.515  -8.296  24.766  1.00 67.76  ? 225 MET C SD   1 
ATOM   3208  C  CE   . MET C 1 18  ? 82.123  -7.834  26.382  1.00 66.97  ? 225 MET C CE   1 
ATOM   3209  N  N    . ASN C 1 19  ? 80.899  -11.918 28.858  1.00 60.44  ? 226 ASN C N    1 
ATOM   3210  C  CA   . ASN C 1 19  ? 81.879  -12.745 29.595  1.00 58.59  ? 226 ASN C CA   1 
ATOM   3211  C  C    . ASN C 1 19  ? 81.383  -14.193 29.618  1.00 56.28  ? 226 ASN C C    1 
ATOM   3212  O  O    . ASN C 1 19  ? 82.176  -15.067 29.276  1.00 60.19  ? 226 ASN C O    1 
ATOM   3213  C  CB   . ASN C 1 19  ? 82.196  -12.138 30.964  1.00 62.69  ? 226 ASN C CB   1 
ATOM   3214  C  CG   . ASN C 1 19  ? 82.743  -10.728 30.885  1.00 67.48  ? 226 ASN C CG   1 
ATOM   3215  O  OD1  . ASN C 1 19  ? 83.239  -10.300 29.847  1.00 67.67  ? 226 ASN C OD1  1 
ATOM   3216  N  ND2  . ASN C 1 19  ? 82.656  -9.996  31.981  1.00 63.35  ? 226 ASN C ND2  1 
ATOM   3217  N  N    . SER C 1 20  ? 80.126  -14.442 29.978  1.00 53.12  ? 227 SER C N    1 
ATOM   3218  C  CA   . SER C 1 20  ? 79.696  -15.838 30.060  1.00 58.30  ? 227 SER C CA   1 
ATOM   3219  C  C    . SER C 1 20  ? 79.703  -16.493 28.684  1.00 55.92  ? 227 SER C C    1 
ATOM   3220  O  O    . SER C 1 20  ? 80.061  -17.667 28.551  1.00 56.75  ? 227 SER C O    1 
ATOM   3221  C  CB   . SER C 1 20  ? 78.304  -15.968 30.694  1.00 60.47  ? 227 SER C CB   1 
ATOM   3222  O  OG   . SER C 1 20  ? 78.116  -15.120 31.815  1.00 62.16  ? 227 SER C OG   1 
ATOM   3223  N  N    . LEU C 1 21  ? 79.315  -15.752 27.645  1.00 56.11  ? 228 LEU C N    1 
ATOM   3224  C  CA   . LEU C 1 21  ? 79.413  -16.307 26.302  1.00 55.64  ? 228 LEU C CA   1 
ATOM   3225  C  C    . LEU C 1 21  ? 80.862  -16.546 25.916  1.00 54.45  ? 228 LEU C C    1 
ATOM   3226  O  O    . LEU C 1 21  ? 81.191  -17.604 25.365  1.00 58.86  ? 228 LEU C O    1 
ATOM   3227  C  CB   . LEU C 1 21  ? 78.752  -15.389 25.270  1.00 54.92  ? 228 LEU C CB   1 
ATOM   3228  C  CG   . LEU C 1 21  ? 78.891  -15.976 23.855  1.00 52.75  ? 228 LEU C CG   1 
ATOM   3229  C  CD1  . LEU C 1 21  ? 77.963  -17.175 23.667  1.00 50.08  ? 228 LEU C CD1  1 
ATOM   3230  C  CD2  . LEU C 1 21  ? 78.664  -14.952 22.775  1.00 54.18  ? 228 LEU C CD2  1 
ATOM   3231  N  N    . LEU C 1 22  ? 81.733  -15.567 26.189  1.00 54.19  ? 229 LEU C N    1 
ATOM   3232  C  CA   . LEU C 1 22  ? 83.125  -15.650 25.749  1.00 59.81  ? 229 LEU C CA   1 
ATOM   3233  C  C    . LEU C 1 22  ? 83.818  -16.862 26.340  1.00 57.04  ? 229 LEU C C    1 
ATOM   3234  O  O    . LEU C 1 22  ? 84.579  -17.553 25.652  1.00 56.08  ? 229 LEU C O    1 
ATOM   3235  C  CB   . LEU C 1 22  ? 83.876  -14.371 26.119  1.00 58.40  ? 229 LEU C CB   1 
ATOM   3236  C  CG   . LEU C 1 22  ? 83.586  -13.245 25.135  1.00 54.12  ? 229 LEU C CG   1 
ATOM   3237  C  CD1  . LEU C 1 22  ? 84.056  -11.906 25.665  1.00 61.31  ? 229 LEU C CD1  1 
ATOM   3238  C  CD2  . LEU C 1 22  ? 84.283  -13.586 23.860  1.00 56.56  ? 229 LEU C CD2  1 
ATOM   3239  N  N    . GLN C 1 23  ? 83.540  -17.160 27.604  1.00 56.88  ? 230 GLN C N    1 
ATOM   3240  C  CA   . GLN C 1 23  ? 84.159  -18.313 28.233  1.00 51.67  ? 230 GLN C CA   1 
ATOM   3241  C  C    . GLN C 1 23  ? 83.590  -19.612 27.672  1.00 59.66  ? 230 GLN C C    1 
ATOM   3242  O  O    . GLN C 1 23  ? 84.340  -20.549 27.353  1.00 55.24  ? 230 GLN C O    1 
ATOM   3243  C  CB   . GLN C 1 23  ? 83.956  -18.221 29.735  1.00 58.05  ? 230 GLN C CB   1 
ATOM   3244  C  CG   . GLN C 1 23  ? 84.721  -17.068 30.366  1.00 59.83  ? 230 GLN C CG   1 
ATOM   3245  C  CD   . GLN C 1 23  ? 86.156  -17.429 30.708  1.00 62.23  ? 230 GLN C CD   1 
ATOM   3246  O  OE1  . GLN C 1 23  ? 86.652  -18.495 30.329  1.00 62.20  ? 230 GLN C OE1  1 
ATOM   3247  N  NE2  . GLN C 1 23  ? 86.827  -16.549 31.451  1.00 65.41  ? 230 GLN C NE2  1 
ATOM   3248  N  N    . THR C 1 24  ? 82.257  -19.692 27.553  1.00 61.11  ? 231 THR C N    1 
ATOM   3249  C  CA   . THR C 1 24  ? 81.632  -20.798 26.828  1.00 52.93  ? 231 THR C CA   1 
ATOM   3250  C  C    . THR C 1 24  ? 82.333  -21.029 25.494  1.00 55.27  ? 231 THR C C    1 
ATOM   3251  O  O    . THR C 1 24  ? 82.746  -22.148 25.183  1.00 52.42  ? 231 THR C O    1 
ATOM   3252  C  CB   . THR C 1 24  ? 80.146  -20.508 26.589  1.00 54.40  ? 231 THR C CB   1 
ATOM   3253  O  OG1  . THR C 1 24  ? 79.488  -20.272 27.833  1.00 55.66  ? 231 THR C OG1  1 
ATOM   3254  C  CG2  . THR C 1 24  ? 79.466  -21.678 25.883  1.00 48.69  ? 231 THR C CG2  1 
ATOM   3255  N  N    . LEU C 1 25  ? 82.515  -19.963 24.706  1.00 51.24  ? 232 LEU C N    1 
ATOM   3256  C  CA   . LEU C 1 25  ? 83.084  -20.149 23.377  1.00 55.75  ? 232 LEU C CA   1 
ATOM   3257  C  C    . LEU C 1 25  ? 84.583  -20.436 23.418  1.00 55.96  ? 232 LEU C C    1 
ATOM   3258  O  O    . LEU C 1 25  ? 85.079  -21.236 22.618  1.00 60.17  ? 232 LEU C O    1 
ATOM   3259  C  CB   . LEU C 1 25  ? 82.793  -18.932 22.500  1.00 57.89  ? 232 LEU C CB   1 
ATOM   3260  C  CG   . LEU C 1 25  ? 81.312  -18.766 22.144  1.00 54.32  ? 232 LEU C CG   1 
ATOM   3261  C  CD1  . LEU C 1 25  ? 81.113  -17.686 21.092  1.00 48.08  ? 232 LEU C CD1  1 
ATOM   3262  C  CD2  . LEU C 1 25  ? 80.732  -20.110 21.685  1.00 52.06  ? 232 LEU C CD2  1 
ATOM   3263  N  N    . PHE C 1 26  ? 85.327  -19.799 24.320  1.00 57.97  ? 233 PHE C N    1 
ATOM   3264  C  CA   . PHE C 1 26  ? 86.762  -20.071 24.388  1.00 56.72  ? 233 PHE C CA   1 
ATOM   3265  C  C    . PHE C 1 26  ? 87.018  -21.544 24.673  1.00 57.72  ? 233 PHE C C    1 
ATOM   3266  O  O    . PHE C 1 26  ? 87.948  -22.149 24.124  1.00 55.19  ? 233 PHE C O    1 
ATOM   3267  N  N    . PHE C 1 27  ? 86.151  -22.136 25.489  1.00 60.20  ? 234 PHE C N    1 
ATOM   3268  C  CA   . PHE C 1 27  ? 86.337  -23.551 25.895  1.00 60.39  ? 234 PHE C CA   1 
ATOM   3269  C  C    . PHE C 1 27  ? 85.802  -24.502 24.825  1.00 59.11  ? 234 PHE C C    1 
ATOM   3270  O  O    . PHE C 1 27  ? 85.860  -25.703 25.064  1.00 58.76  ? 234 PHE C O    1 
ATOM   3271  C  CB   . PHE C 1 27  ? 85.798  -23.763 27.310  1.00 59.71  ? 234 PHE C CB   1 
ATOM   3272  C  CG   . PHE C 1 27  ? 86.707  -23.173 28.352  1.00 58.87  ? 234 PHE C CG   1 
ATOM   3273  C  CD1  . PHE C 1 27  ? 88.066  -23.431 28.324  1.00 60.11  ? 234 PHE C CD1  1 
ATOM   3274  C  CD2  . PHE C 1 27  ? 86.215  -22.332 29.332  1.00 63.73  ? 234 PHE C CD2  1 
ATOM   3275  C  CE1  . PHE C 1 27  ? 88.912  -22.881 29.271  1.00 62.72  ? 234 PHE C CE1  1 
ATOM   3276  C  CE2  . PHE C 1 27  ? 87.063  -21.779 30.274  1.00 60.57  ? 234 PHE C CE2  1 
ATOM   3277  C  CZ   . PHE C 1 27  ? 88.407  -22.054 30.245  1.00 59.66  ? 234 PHE C CZ   1 
ATOM   3278  N  N    . THR C 1 28  ? 85.268  -23.989 23.719  1.00 52.17  ? 235 THR C N    1 
ATOM   3279  C  CA   . THR C 1 28  ? 84.955  -24.878 22.572  1.00 57.48  ? 235 THR C CA   1 
ATOM   3280  C  C    . THR C 1 28  ? 86.289  -24.878 21.827  1.00 56.55  ? 235 THR C C    1 
ATOM   3281  O  O    . THR C 1 28  ? 86.430  -24.122 20.878  1.00 55.57  ? 235 THR C O    1 
ATOM   3282  C  CB   . THR C 1 28  ? 83.662  -24.475 21.849  1.00 55.54  ? 235 THR C CB   1 
ATOM   3283  O  OG1  . THR C 1 28  ? 83.782  -23.168 21.294  1.00 66.07  ? 235 THR C OG1  1 
ATOM   3284  C  CG2  . THR C 1 28  ? 82.454  -24.517 22.758  1.00 47.31  ? 235 THR C CG2  1 
ATOM   3285  N  N    . ASN C 1 29  ? 87.238  -25.676 22.292  1.00 62.41  ? 236 ASN C N    1 
ATOM   3286  C  CA   . ASN C 1 29  ? 88.635  -25.656 21.795  1.00 56.23  ? 236 ASN C CA   1 
ATOM   3287  C  C    . ASN C 1 29  ? 88.759  -25.664 20.273  1.00 56.91  ? 236 ASN C C    1 
ATOM   3288  O  O    . ASN C 1 29  ? 89.608  -24.934 19.772  1.00 61.14  ? 236 ASN C O    1 
ATOM   3289  C  CB   . ASN C 1 29  ? 89.395  -26.797 22.460  1.00 62.94  ? 236 ASN C CB   1 
ATOM   3290  C  CG   . ASN C 1 29  ? 89.512  -26.661 23.964  1.00 65.53  ? 236 ASN C CG   1 
ATOM   3291  O  OD1  . ASN C 1 29  ? 89.085  -25.668 24.544  1.00 70.22  ? 236 ASN C OD1  1 
ATOM   3292  N  ND2  . ASN C 1 29  ? 90.099  -27.653 24.608  1.00 60.65  ? 236 ASN C ND2  1 
ATOM   3293  N  N    . GLN C 1 30  ? 87.979  -26.483 19.579  1.00 60.49  ? 237 GLN C N    1 
ATOM   3294  C  CA   . GLN C 1 30  ? 88.068  -26.570 18.101  1.00 61.80  ? 237 GLN C CA   1 
ATOM   3295  C  C    . GLN C 1 30  ? 87.774  -25.188 17.517  1.00 59.04  ? 237 GLN C C    1 
ATOM   3296  O  O    . GLN C 1 30  ? 88.495  -24.781 16.601  1.00 61.97  ? 237 GLN C O    1 
ATOM   3297  C  CB   . GLN C 1 30  ? 87.124  -27.656 17.591  1.00 61.21  ? 237 GLN C CB   1 
ATOM   3298  C  CG   . GLN C 1 30  ? 87.321  -28.018 16.128  1.00 60.68  ? 237 GLN C CG   1 
ATOM   3299  C  CD   . GLN C 1 30  ? 86.739  -29.365 15.777  1.00 64.04  ? 237 GLN C CD   1 
ATOM   3300  O  OE1  . GLN C 1 30  ? 86.175  -30.063 16.615  1.00 67.09  ? 237 GLN C OE1  1 
ATOM   3301  N  NE2  . GLN C 1 30  ? 86.872  -29.744 14.518  1.00 68.00  ? 237 GLN C NE2  1 
ATOM   3302  N  N    . LEU C 1 31  ? 86.765  -24.501 18.050  1.00 55.67  ? 238 LEU C N    1 
ATOM   3303  C  CA   . LEU C 1 31  ? 86.433  -23.135 17.592  1.00 56.94  ? 238 LEU C CA   1 
ATOM   3304  C  C    . LEU C 1 31  ? 87.578  -22.206 17.972  1.00 59.19  ? 238 LEU C C    1 
ATOM   3305  O  O    . LEU C 1 31  ? 87.976  -21.424 17.114  1.00 60.31  ? 238 LEU C O    1 
ATOM   3306  C  CB   . LEU C 1 31  ? 85.133  -22.670 18.247  1.00 49.96  ? 238 LEU C CB   1 
ATOM   3307  C  CG   . LEU C 1 31  ? 84.626  -21.301 17.808  1.00 48.53  ? 238 LEU C CG   1 
ATOM   3308  C  CD1  . LEU C 1 31  ? 84.314  -21.298 16.324  1.00 48.66  ? 238 LEU C CD1  1 
ATOM   3309  C  CD2  . LEU C 1 31  ? 83.406  -20.892 18.611  1.00 54.59  ? 238 LEU C CD2  1 
ATOM   3310  N  N    . ARG C 1 32  ? 88.080  -22.299 19.204  1.00 59.83  ? 239 ARG C N    1 
ATOM   3311  C  CA   . ARG C 1 32  ? 89.212  -21.440 19.529  1.00 64.36  ? 239 ARG C CA   1 
ATOM   3312  C  C    . ARG C 1 32  ? 90.311  -21.563 18.476  1.00 62.97  ? 239 ARG C C    1 
ATOM   3313  O  O    . ARG C 1 32  ? 90.729  -20.567 17.879  1.00 57.95  ? 239 ARG C O    1 
ATOM   3314  C  CB   . ARG C 1 32  ? 89.743  -21.797 20.921  1.00 62.39  ? 239 ARG C CB   1 
ATOM   3315  C  CG   . ARG C 1 32  ? 90.668  -20.762 21.524  1.00 60.73  ? 239 ARG C CG   1 
ATOM   3316  C  CD   . ARG C 1 32  ? 91.578  -21.415 22.532  1.00 59.45  ? 239 ARG C CD   1 
ATOM   3317  N  NE   . ARG C 1 32  ? 90.830  -21.957 23.657  1.00 54.97  ? 239 ARG C NE   1 
ATOM   3318  C  CZ   . ARG C 1 32  ? 91.390  -22.636 24.646  1.00 56.02  ? 239 ARG C CZ   1 
ATOM   3319  N  NH1  . ARG C 1 32  ? 92.697  -22.850 24.638  1.00 61.67  ? 239 ARG C NH1  1 
ATOM   3320  N  NH2  . ARG C 1 32  ? 90.647  -23.096 25.641  1.00 58.92  ? 239 ARG C NH2  1 
ATOM   3321  N  N    . LYS C 1 33  ? 90.757  -22.794 18.209  1.00 66.00  ? 240 LYS C N    1 
ATOM   3322  C  CA   . LYS C 1 33  ? 91.839  -23.015 17.252  1.00 63.82  ? 240 LYS C CA   1 
ATOM   3323  C  C    . LYS C 1 33  ? 91.531  -22.374 15.905  1.00 66.53  ? 240 LYS C C    1 
ATOM   3324  O  O    . LYS C 1 33  ? 92.420  -21.798 15.262  1.00 69.24  ? 240 LYS C O    1 
ATOM   3325  C  CB   . LYS C 1 33  ? 92.094  -24.513 17.093  1.00 66.26  ? 240 LYS C CB   1 
ATOM   3326  C  CG   . LYS C 1 33  ? 93.473  -24.875 16.577  1.00 74.87  ? 240 LYS C CG   1 
ATOM   3327  C  CD   . LYS C 1 33  ? 93.906  -26.249 17.097  1.00 69.32  ? 240 LYS C CD   1 
ATOM   3328  N  N    . ALA C 1 34  ? 90.272  -22.432 15.473  1.00 65.63  ? 241 ALA C N    1 
ATOM   3329  C  CA   . ALA C 1 34  ? 89.935  -21.911 14.156  1.00 61.13  ? 241 ALA C CA   1 
ATOM   3330  C  C    . ALA C 1 34  ? 89.932  -20.394 14.144  1.00 66.09  ? 241 ALA C C    1 
ATOM   3331  O  O    . ALA C 1 34  ? 90.337  -19.785 13.148  1.00 68.97  ? 241 ALA C O    1 
ATOM   3332  C  CB   . ALA C 1 34  ? 88.585  -22.455 13.699  1.00 63.23  ? 241 ALA C CB   1 
ATOM   3333  N  N    . VAL C 1 35  ? 89.482  -19.769 15.238  1.00 66.82  ? 242 VAL C N    1 
ATOM   3334  C  CA   . VAL C 1 35  ? 89.559  -18.310 15.352  1.00 66.92  ? 242 VAL C CA   1 
ATOM   3335  C  C    . VAL C 1 35  ? 91.015  -17.854 15.281  1.00 68.84  ? 242 VAL C C    1 
ATOM   3336  O  O    . VAL C 1 35  ? 91.343  -16.864 14.605  1.00 64.73  ? 242 VAL C O    1 
ATOM   3337  C  CB   . VAL C 1 35  ? 88.870  -17.839 16.651  1.00 63.29  ? 242 VAL C CB   1 
ATOM   3338  C  CG1  . VAL C 1 35  ? 89.041  -16.344 16.841  1.00 59.23  ? 242 VAL C CG1  1 
ATOM   3339  C  CG2  . VAL C 1 35  ? 87.379  -18.209 16.640  1.00 59.55  ? 242 VAL C CG2  1 
ATOM   3340  N  N    . TYR C 1 36  ? 91.913  -18.589 15.959  1.00 67.83  ? 243 TYR C N    1 
ATOM   3341  C  CA   . TYR C 1 36  ? 93.340  -18.270 15.925  1.00 68.17  ? 243 TYR C CA   1 
ATOM   3342  C  C    . TYR C 1 36  ? 93.873  -18.243 14.489  1.00 73.85  ? 243 TYR C C    1 
ATOM   3343  O  O    . TYR C 1 36  ? 94.645  -17.349 14.123  1.00 77.09  ? 243 TYR C O    1 
ATOM   3344  C  CB   . TYR C 1 36  ? 94.143  -19.283 16.750  1.00 64.79  ? 243 TYR C CB   1 
ATOM   3345  C  CG   . TYR C 1 36  ? 94.089  -19.146 18.258  1.00 69.55  ? 243 TYR C CG   1 
ATOM   3346  C  CD1  . TYR C 1 36  ? 93.925  -17.917 18.865  1.00 62.98  ? 243 TYR C CD1  1 
ATOM   3347  C  CD2  . TYR C 1 36  ? 94.224  -20.272 19.079  1.00 72.08  ? 243 TYR C CD2  1 
ATOM   3348  C  CE1  . TYR C 1 36  ? 93.874  -17.809 20.241  1.00 66.63  ? 243 TYR C CE1  1 
ATOM   3349  C  CE2  . TYR C 1 36  ? 94.178  -20.172 20.462  1.00 68.08  ? 243 TYR C CE2  1 
ATOM   3350  C  CZ   . TYR C 1 36  ? 94.000  -18.934 21.037  1.00 69.57  ? 243 TYR C CZ   1 
ATOM   3351  O  OH   . TYR C 1 36  ? 93.943  -18.809 22.411  1.00 66.66  ? 243 TYR C OH   1 
ATOM   3352  N  N    . MET C 1 37  ? 93.482  -19.217 13.663  1.00 71.76  ? 244 MET C N    1 
ATOM   3353  C  CA   . MET C 1 37  ? 94.035  -19.354 12.321  1.00 66.35  ? 244 MET C CA   1 
ATOM   3354  C  C    . MET C 1 37  ? 93.291  -18.527 11.283  1.00 70.87  ? 244 MET C C    1 
ATOM   3355  O  O    . MET C 1 37  ? 93.504  -18.729 10.085  1.00 79.25  ? 244 MET C O    1 
ATOM   3356  C  CB   . MET C 1 37  ? 94.054  -20.827 11.899  1.00 64.52  ? 244 MET C CB   1 
ATOM   3357  N  N    . MET C 1 38  ? 92.444  -17.598 11.698  1.00 71.79  ? 245 MET C N    1 
ATOM   3358  C  CA   . MET C 1 38  ? 91.746  -16.775 10.716  1.00 76.31  ? 245 MET C CA   1 
ATOM   3359  C  C    . MET C 1 38  ? 92.679  -15.695 10.184  1.00 80.92  ? 245 MET C C    1 
ATOM   3360  O  O    . MET C 1 38  ? 93.294  -14.972 10.974  1.00 81.25  ? 245 MET C O    1 
ATOM   3361  C  CB   . MET C 1 38  ? 90.514  -16.110 11.313  1.00 73.77  ? 245 MET C CB   1 
ATOM   3362  C  CG   . MET C 1 38  ? 89.463  -17.051 11.829  1.00 69.79  ? 245 MET C CG   1 
ATOM   3363  S  SD   . MET C 1 38  ? 88.032  -16.083 12.344  1.00 65.78  ? 245 MET C SD   1 
ATOM   3364  C  CE   . MET C 1 38  ? 87.607  -15.175 10.872  1.00 59.31  ? 245 MET C CE   1 
ATOM   3365  N  N    . PRO C 1 39  ? 92.800  -15.548 8.870   1.00 82.12  ? 246 PRO C N    1 
ATOM   3366  C  CA   . PRO C 1 39  ? 93.656  -14.486 8.324   1.00 84.48  ? 246 PRO C CA   1 
ATOM   3367  C  C    . PRO C 1 39  ? 93.141  -13.101 8.692   1.00 81.24  ? 246 PRO C C    1 
ATOM   3368  O  O    . PRO C 1 39  ? 91.974  -12.775 8.476   1.00 86.79  ? 246 PRO C O    1 
ATOM   3369  C  CB   . PRO C 1 39  ? 93.610  -14.730 6.809   1.00 84.75  ? 246 PRO C CB   1 
ATOM   3370  C  CG   . PRO C 1 39  ? 92.516  -15.722 6.580   1.00 80.56  ? 246 PRO C CG   1 
ATOM   3371  C  CD   . PRO C 1 39  ? 92.363  -16.504 7.843   1.00 81.32  ? 246 PRO C CD   1 
ATOM   3372  N  N    . THR C 1 40  ? 94.034  -12.289 9.248   1.00 84.98  ? 247 THR C N    1 
ATOM   3373  C  CA   . THR C 1 40  ? 93.739  -10.920 9.674   1.00 85.68  ? 247 THR C CA   1 
ATOM   3374  C  C    . THR C 1 40  ? 95.017  -10.071 9.627   1.00 86.07  ? 247 THR C C    1 
ATOM   3375  O  O    . THR C 1 40  ? 95.046  -8.982  9.047   1.00 89.19  ? 247 THR C O    1 
ATOM   3376  C  CB   . THR C 1 40  ? 93.163  -10.870 11.108  1.00 83.21  ? 247 THR C CB   1 
ATOM   3377  O  OG1  . THR C 1 40  ? 93.861  -11.810 11.938  1.00 90.85  ? 247 THR C OG1  1 
ATOM   3378  C  CG2  . THR C 1 40  ? 91.674  -11.185 11.126  1.00 84.53  ? 247 THR C CG2  1 
ATOM   3379  N  N    . SER C 1 46  ? 91.888  -2.340  16.520  1.00 83.72  ? 253 SER C N    1 
ATOM   3380  C  CA   . SER C 1 46  ? 90.903  -3.450  16.427  1.00 86.62  ? 253 SER C CA   1 
ATOM   3381  C  C    . SER C 1 46  ? 89.615  -2.963  15.762  1.00 90.94  ? 253 SER C C    1 
ATOM   3382  O  O    . SER C 1 46  ? 88.794  -2.322  16.444  1.00 91.12  ? 253 SER C O    1 
ATOM   3383  C  CB   . SER C 1 46  ? 90.628  -4.070  17.770  1.00 84.41  ? 253 SER C CB   1 
ATOM   3384  O  OG   . SER C 1 46  ? 90.540  -5.483  17.663  1.00 81.60  ? 253 SER C OG   1 
ATOM   3385  N  N    . LYS C 1 47  ? 89.458  -3.263  14.475  1.00 88.35  ? 254 LYS C N    1 
ATOM   3386  C  CA   . LYS C 1 47  ? 88.243  -2.907  13.753  1.00 85.63  ? 254 LYS C CA   1 
ATOM   3387  C  C    . LYS C 1 47  ? 87.539  -4.126  13.150  1.00 81.74  ? 254 LYS C C    1 
ATOM   3388  O  O    . LYS C 1 47  ? 86.731  -3.976  12.230  1.00 82.66  ? 254 LYS C O    1 
ATOM   3389  N  N    . SER C 1 48  ? 87.834  -5.328  13.643  1.00 76.85  ? 255 SER C N    1 
ATOM   3390  C  CA   . SER C 1 48  ? 87.157  -6.544  13.211  1.00 76.03  ? 255 SER C CA   1 
ATOM   3391  C  C    . SER C 1 48  ? 86.902  -7.418  14.427  1.00 74.83  ? 255 SER C C    1 
ATOM   3392  O  O    . SER C 1 48  ? 87.695  -7.431  15.370  1.00 78.14  ? 255 SER C O    1 
ATOM   3393  C  CB   . SER C 1 48  ? 87.978  -7.337  12.188  1.00 74.82  ? 255 SER C CB   1 
ATOM   3394  O  OG   . SER C 1 48  ? 88.871  -8.216  12.852  1.00 74.89  ? 255 SER C OG   1 
ATOM   3395  N  N    . VAL C 1 49  ? 85.795  -8.155  14.399  1.00 75.76  ? 256 VAL C N    1 
ATOM   3396  C  CA   . VAL C 1 49  ? 85.423  -9.010  15.528  1.00 70.22  ? 256 VAL C CA   1 
ATOM   3397  C  C    . VAL C 1 49  ? 86.337  -10.228 15.643  1.00 65.51  ? 256 VAL C C    1 
ATOM   3398  O  O    . VAL C 1 49  ? 86.691  -10.603 16.768  1.00 66.58  ? 256 VAL C O    1 
ATOM   3399  C  CB   . VAL C 1 49  ? 83.953  -9.451  15.448  1.00 65.70  ? 256 VAL C CB   1 
ATOM   3400  C  CG1  . VAL C 1 49  ? 83.599  -10.303 16.662  1.00 69.42  ? 256 VAL C CG1  1 
ATOM   3401  C  CG2  . VAL C 1 49  ? 83.042  -8.253  15.400  1.00 68.77  ? 256 VAL C CG2  1 
ATOM   3402  N  N    . PRO C 1 50  ? 86.730  -10.901 14.553  1.00 67.01  ? 257 PRO C N    1 
ATOM   3403  C  CA   . PRO C 1 50  ? 87.655  -12.039 14.733  1.00 67.07  ? 257 PRO C CA   1 
ATOM   3404  C  C    . PRO C 1 50  ? 88.975  -11.639 15.373  1.00 69.29  ? 257 PRO C C    1 
ATOM   3405  O  O    . PRO C 1 50  ? 89.516  -12.402 16.180  1.00 72.15  ? 257 PRO C O    1 
ATOM   3406  C  CB   . PRO C 1 50  ? 87.857  -12.569 13.306  1.00 66.55  ? 257 PRO C CB   1 
ATOM   3407  C  CG   . PRO C 1 50  ? 86.663  -12.110 12.546  1.00 61.43  ? 257 PRO C CG   1 
ATOM   3408  C  CD   . PRO C 1 50  ? 86.274  -10.791 13.152  1.00 68.74  ? 257 PRO C CD   1 
ATOM   3409  N  N    . LEU C 1 51  ? 89.512  -10.461 15.045  1.00 70.14  ? 258 LEU C N    1 
ATOM   3410  C  CA   . LEU C 1 51  ? 90.739  -10.009 15.698  1.00 72.18  ? 258 LEU C CA   1 
ATOM   3411  C  C    . LEU C 1 51  ? 90.532  -9.871  17.201  1.00 70.77  ? 258 LEU C C    1 
ATOM   3412  O  O    . LEU C 1 51  ? 91.347  -10.350 18.004  1.00 66.73  ? 258 LEU C O    1 
ATOM   3413  N  N    . ALA C 1 52  ? 89.423  -9.259  17.582  1.00 66.75  ? 259 ALA C N    1 
ATOM   3414  C  CA   . ALA C 1 52  ? 89.121  -9.109  19.016  1.00 66.26  ? 259 ALA C CA   1 
ATOM   3415  C  C    . ALA C 1 52  ? 89.011  -10.487 19.661  1.00 70.71  ? 259 ALA C C    1 
ATOM   3416  O  O    . ALA C 1 52  ? 89.693  -10.701 20.658  1.00 70.33  ? 259 ALA C O    1 
ATOM   3417  C  CB   . ALA C 1 52  ? 87.861  -8.324  19.165  1.00 66.19  ? 259 ALA C CB   1 
ATOM   3418  N  N    . LEU C 1 53  ? 88.226  -11.385 19.080  1.00 63.04  ? 260 LEU C N    1 
ATOM   3419  C  CA   . LEU C 1 53  ? 88.096  -12.743 19.644  1.00 57.15  ? 260 LEU C CA   1 
ATOM   3420  C  C    . LEU C 1 53  ? 89.491  -13.342 19.768  1.00 59.07  ? 260 LEU C C    1 
ATOM   3421  O  O    . LEU C 1 53  ? 89.745  -13.993 20.767  1.00 59.77  ? 260 LEU C O    1 
ATOM   3422  C  CB   . LEU C 1 53  ? 87.204  -13.582 18.731  1.00 61.60  ? 260 LEU C CB   1 
ATOM   3423  C  CG   . LEU C 1 53  ? 85.701  -13.404 18.906  1.00 59.28  ? 260 LEU C CG   1 
ATOM   3424  C  CD1  . LEU C 1 53  ? 84.972  -14.672 18.504  1.00 59.86  ? 260 LEU C CD1  1 
ATOM   3425  C  CD2  . LEU C 1 53  ? 85.361  -13.035 20.338  1.00 61.04  ? 260 LEU C CD2  1 
ATOM   3426  N  N    . GLN C 1 54  ? 90.354  -13.104 18.782  1.00 62.08  ? 261 GLN C N    1 
ATOM   3427  C  CA   . GLN C 1 54  ? 91.716  -13.625 18.827  1.00 65.12  ? 261 GLN C CA   1 
ATOM   3428  C  C    . GLN C 1 54  ? 92.458  -13.085 20.043  1.00 65.26  ? 261 GLN C C    1 
ATOM   3429  O  O    . GLN C 1 54  ? 92.945  -13.852 20.881  1.00 64.66  ? 261 GLN C O    1 
ATOM   3430  C  CB   . GLN C 1 54  ? 92.453  -13.280 17.526  1.00 64.26  ? 261 GLN C CB   1 
ATOM   3431  C  CG   . GLN C 1 54  ? 92.012  -14.125 16.340  1.00 67.49  ? 261 GLN C CG   1 
ATOM   3432  C  CD   . GLN C 1 54  ? 92.601  -13.696 14.996  1.00 70.57  ? 261 GLN C CD   1 
ATOM   3433  O  OE1  . GLN C 1 54  ? 92.871  -12.518 14.745  1.00 65.47  ? 261 GLN C OE1  1 
ATOM   3434  N  NE2  . GLN C 1 54  ? 92.769  -14.667 14.110  1.00 73.95  ? 261 GLN C NE2  1 
ATOM   3435  N  N    . ARG C 1 55  ? 92.526  -11.755 20.171  1.00 67.52  ? 262 ARG C N    1 
ATOM   3436  C  CA   . ARG C 1 55  ? 93.101  -11.143 21.371  1.00 70.59  ? 262 ARG C CA   1 
ATOM   3437  C  C    . ARG C 1 55  ? 92.501  -11.738 22.644  1.00 67.13  ? 262 ARG C C    1 
ATOM   3438  O  O    . ARG C 1 55  ? 93.232  -12.145 23.560  1.00 65.34  ? 262 ARG C O    1 
ATOM   3439  C  CB   . ARG C 1 55  ? 92.893  -9.625  21.336  1.00 63.47  ? 262 ARG C CB   1 
ATOM   3440  C  CG   . ARG C 1 55  ? 93.557  -8.853  22.471  1.00 63.10  ? 262 ARG C CG   1 
ATOM   3441  N  N    . VAL C 1 56  ? 91.176  -11.803 22.710  1.00 59.86  ? 263 VAL C N    1 
ATOM   3442  C  CA   . VAL C 1 56  ? 90.529  -12.259 23.970  1.00 62.37  ? 263 VAL C CA   1 
ATOM   3443  C  C    . VAL C 1 56  ? 90.907  -13.716 24.229  1.00 65.20  ? 263 VAL C C    1 
ATOM   3444  O  O    . VAL C 1 56  ? 91.224  -14.031 25.372  1.00 68.24  ? 263 VAL C O    1 
ATOM   3445  C  CB   . VAL C 1 56  ? 89.007  -12.030 23.936  1.00 60.65  ? 263 VAL C CB   1 
ATOM   3446  C  CG1  . VAL C 1 56  ? 88.300  -12.604 25.151  1.00 54.62  ? 263 VAL C CG1  1 
ATOM   3447  C  CG2  . VAL C 1 56  ? 88.669  -10.557 23.786  1.00 66.27  ? 263 VAL C CG2  1 
ATOM   3448  N  N    . PHE C 1 57  ? 90.891  -14.561 23.205  1.00 62.90  ? 264 PHE C N    1 
ATOM   3449  C  CA   . PHE C 1 57  ? 91.154  -15.974 23.459  1.00 65.46  ? 264 PHE C CA   1 
ATOM   3450  C  C    . PHE C 1 57  ? 92.596  -16.174 23.901  1.00 70.12  ? 264 PHE C C    1 
ATOM   3451  O  O    . PHE C 1 57  ? 92.870  -16.922 24.852  1.00 68.87  ? 264 PHE C O    1 
ATOM   3452  C  CB   . PHE C 1 57  ? 90.864  -16.813 22.205  1.00 70.93  ? 264 PHE C CB   1 
ATOM   3453  C  CG   . PHE C 1 57  ? 89.384  -17.027 21.901  1.00 64.56  ? 264 PHE C CG   1 
ATOM   3454  C  CD1  . PHE C 1 57  ? 88.387  -16.542 22.740  1.00 63.86  ? 264 PHE C CD1  1 
ATOM   3455  C  CD2  . PHE C 1 57  ? 89.005  -17.730 20.757  1.00 64.07  ? 264 PHE C CD2  1 
ATOM   3456  C  CE1  . PHE C 1 57  ? 87.031  -16.749 22.438  1.00 62.65  ? 264 PHE C CE1  1 
ATOM   3457  C  CE2  . PHE C 1 57  ? 87.659  -17.939 20.452  1.00 65.18  ? 264 PHE C CE2  1 
ATOM   3458  C  CZ   . PHE C 1 57  ? 86.672  -17.443 21.290  1.00 60.59  ? 264 PHE C CZ   1 
ATOM   3459  N  N    . TYR C 1 58  ? 93.533  -15.512 23.214  1.00 70.19  ? 265 TYR C N    1 
ATOM   3460  C  CA   . TYR C 1 58  ? 94.937  -15.555 23.613  1.00 71.70  ? 265 TYR C CA   1 
ATOM   3461  C  C    . TYR C 1 58  ? 95.117  -15.068 25.049  1.00 73.47  ? 265 TYR C C    1 
ATOM   3462  O  O    . TYR C 1 58  ? 95.779  -15.721 25.871  1.00 69.06  ? 265 TYR C O    1 
ATOM   3463  C  CB   . TYR C 1 58  ? 95.770  -14.706 22.653  1.00 68.50  ? 265 TYR C CB   1 
ATOM   3464  C  CG   . TYR C 1 58  ? 97.257  -14.797 22.899  1.00 72.66  ? 265 TYR C CG   1 
ATOM   3465  C  CD1  . TYR C 1 58  ? 97.870  -14.054 23.903  1.00 76.15  ? 265 TYR C CD1  1 
ATOM   3466  C  CD2  . TYR C 1 58  ? 98.047  -15.635 22.136  1.00 77.90  ? 265 TYR C CD2  1 
ATOM   3467  C  CE1  . TYR C 1 58  ? 99.232  -14.142 24.127  1.00 76.82  ? 265 TYR C CE1  1 
ATOM   3468  C  CE2  . TYR C 1 58  ? 99.406  -15.725 22.343  1.00 79.87  ? 265 TYR C CE2  1 
ATOM   3469  C  CZ   . TYR C 1 58  ? 99.997  -14.983 23.337  1.00 81.11  ? 265 TYR C CZ   1 
ATOM   3470  O  OH   . TYR C 1 58  ? 101.361 -15.099 23.530  1.00 88.76  ? 265 TYR C OH   1 
ATOM   3471  N  N    . GLU C 1 59  ? 94.546  -13.905 25.365  1.00 65.26  ? 266 GLU C N    1 
ATOM   3472  C  CA   . GLU C 1 59  ? 94.742  -13.365 26.699  1.00 66.56  ? 266 GLU C CA   1 
ATOM   3473  C  C    . GLU C 1 59  ? 94.000  -14.188 27.748  1.00 72.10  ? 266 GLU C C    1 
ATOM   3474  O  O    . GLU C 1 59  ? 94.466  -14.294 28.891  1.00 74.47  ? 266 GLU C O    1 
ATOM   3475  C  CB   . GLU C 1 59  ? 94.335  -11.893 26.714  1.00 65.63  ? 266 GLU C CB   1 
ATOM   3476  C  CG   . GLU C 1 59  ? 95.378  -10.996 26.032  1.00 67.51  ? 266 GLU C CG   1 
ATOM   3477  C  CD   . GLU C 1 59  ? 95.138  -9.504  26.237  1.00 73.49  ? 266 GLU C CD   1 
ATOM   3478  O  OE1  . GLU C 1 59  ? 94.670  -9.117  27.342  1.00 74.23  ? 266 GLU C OE1  1 
ATOM   3479  O  OE2  . GLU C 1 59  ? 95.420  -8.723  25.285  1.00 64.05  ? 266 GLU C OE2  1 
ATOM   3480  N  N    . LEU C 1 60  ? 92.936  -14.872 27.343  1.00 64.77  ? 267 LEU C N    1 
ATOM   3481  C  CA   . LEU C 1 60  ? 92.261  -15.794 28.285  1.00 66.45  ? 267 LEU C CA   1 
ATOM   3482  C  C    . LEU C 1 60  ? 93.157  -17.020 28.478  1.00 68.12  ? 267 LEU C C    1 
ATOM   3483  O  O    . LEU C 1 60  ? 92.986  -17.707 29.489  1.00 70.67  ? 267 LEU C O    1 
ATOM   3484  N  N    . GLN C 1 61  ? 94.087  -17.268 27.554  1.00 66.88  ? 268 GLN C N    1 
ATOM   3485  C  CA   . GLN C 1 61  ? 94.945  -18.488 27.626  1.00 67.55  ? 268 GLN C CA   1 
ATOM   3486  C  C    . GLN C 1 61  ? 96.293  -18.195 28.285  1.00 73.39  ? 268 GLN C C    1 
ATOM   3487  O  O    . GLN C 1 61  ? 96.824  -19.100 28.942  1.00 71.62  ? 268 GLN C O    1 
ATOM   3488  C  CB   . GLN C 1 61  ? 95.215  -19.026 26.220  1.00 71.85  ? 268 GLN C CB   1 
ATOM   3489  C  CG   . GLN C 1 61  ? 95.801  -20.426 26.153  1.00 63.53  ? 268 GLN C CG   1 
ATOM   3490  C  CD   . GLN C 1 61  ? 96.053  -20.839 24.724  1.00 75.17  ? 268 GLN C CD   1 
ATOM   3491  O  OE1  . GLN C 1 61  ? 95.196  -20.700 23.857  1.00 68.47  ? 268 GLN C OE1  1 
ATOM   3492  N  NE2  . GLN C 1 61  ? 97.241  -21.358 24.467  1.00 82.10  ? 268 GLN C NE2  1 
ATOM   3493  N  N    . HIS C 1 62  ? 96.833  -16.989 28.114  1.00 71.38  ? 269 HIS C N    1 
ATOM   3494  C  CA   . HIS C 1 62  ? 98.163  -16.748 28.655  1.00 74.92  ? 269 HIS C CA   1 
ATOM   3495  C  C    . HIS C 1 62  ? 98.168  -15.836 29.873  1.00 76.71  ? 269 HIS C C    1 
ATOM   3496  O  O    . HIS C 1 62  ? 98.888  -16.117 30.832  1.00 78.86  ? 269 HIS C O    1 
ATOM   3497  C  CB   . HIS C 1 62  ? 99.071  -16.187 27.555  1.00 74.17  ? 269 HIS C CB   1 
ATOM   3498  C  CG   . HIS C 1 62  ? 99.301  -17.154 26.439  1.00 75.33  ? 269 HIS C CG   1 
ATOM   3499  N  ND1  . HIS C 1 62  ? 98.659  -17.057 25.224  1.00 74.74  ? 269 HIS C ND1  1 
ATOM   3500  C  CD2  . HIS C 1 62  ? 100.062 -18.272 26.374  1.00 82.58  ? 269 HIS C CD2  1 
ATOM   3501  C  CE1  . HIS C 1 62  ? 99.034  -18.059 24.448  1.00 76.39  ? 269 HIS C CE1  1 
ATOM   3502  N  NE2  . HIS C 1 62  ? 99.888  -18.810 25.120  1.00 80.84  ? 269 HIS C NE2  1 
ATOM   3503  N  N    . SER C 1 63  ? 97.356  -14.781 29.889  1.00 75.19  ? 270 SER C N    1 
ATOM   3504  C  CA   . SER C 1 63  ? 97.417  -13.808 30.969  1.00 74.67  ? 270 SER C CA   1 
ATOM   3505  C  C    . SER C 1 63  ? 97.027  -14.450 32.295  1.00 76.88  ? 270 SER C C    1 
ATOM   3506  O  O    . SER C 1 63  ? 96.324  -15.464 32.339  1.00 76.91  ? 270 SER C O    1 
ATOM   3507  C  CB   . SER C 1 63  ? 96.506  -12.616 30.673  1.00 76.26  ? 270 SER C CB   1 
ATOM   3508  O  OG   . SER C 1 63  ? 96.007  -12.014 31.856  1.00 75.41  ? 270 SER C OG   1 
ATOM   3509  N  N    . ASP C 1 64  ? 97.438  -13.809 33.398  1.00 78.35  ? 271 ASP C N    1 
ATOM   3510  C  CA   . ASP C 1 64  ? 97.156  -14.319 34.771  1.00 77.73  ? 271 ASP C CA   1 
ATOM   3511  C  C    . ASP C 1 64  ? 96.168  -13.400 35.497  1.00 73.77  ? 271 ASP C C    1 
ATOM   3512  O  O    . ASP C 1 64  ? 95.526  -13.885 36.437  1.00 69.64  ? 271 ASP C O    1 
ATOM   3513  C  CB   . ASP C 1 64  ? 98.452  -14.486 35.569  1.00 80.30  ? 271 ASP C CB   1 
ATOM   3514  C  CG   . ASP C 1 64  ? 99.246  -13.203 35.748  1.00 83.79  ? 271 ASP C CG   1 
ATOM   3515  O  OD1  . ASP C 1 64  ? 99.762  -12.686 34.741  1.00 82.64  ? 271 ASP C OD1  1 
ATOM   3516  O  OD2  . ASP C 1 64  ? 99.349  -12.735 36.896  1.00 83.66  ? 271 ASP C OD2  1 
ATOM   3517  N  N    . LYS C 1 65  ? 96.106  -12.118 35.139  1.00 74.31  ? 272 LYS C N    1 
ATOM   3518  C  CA   . LYS C 1 65  ? 95.121  -11.202 35.688  1.00 71.56  ? 272 LYS C CA   1 
ATOM   3519  C  C    . LYS C 1 65  ? 93.866  -11.219 34.820  1.00 75.55  ? 272 LYS C C    1 
ATOM   3520  O  O    . LYS C 1 65  ? 93.932  -11.570 33.637  1.00 76.02  ? 272 LYS C O    1 
ATOM   3521  N  N    . PRO C 1 66  ? 92.706  -10.886 35.391  1.00 75.47  ? 273 PRO C N    1 
ATOM   3522  C  CA   . PRO C 1 66  ? 91.459  -10.890 34.609  1.00 68.84  ? 273 PRO C CA   1 
ATOM   3523  C  C    . PRO C 1 66  ? 91.554  -10.098 33.310  1.00 66.67  ? 273 PRO C C    1 
ATOM   3524  O  O    . PRO C 1 66  ? 92.005  -8.952  33.283  1.00 70.11  ? 273 PRO C O    1 
ATOM   3525  C  CB   . PRO C 1 66  ? 90.447  -10.277 35.580  1.00 65.26  ? 273 PRO C CB   1 
ATOM   3526  C  CG   . PRO C 1 66  ? 90.905  -10.803 36.922  1.00 65.02  ? 273 PRO C CG   1 
ATOM   3527  C  CD   . PRO C 1 66  ? 92.436  -10.838 36.843  1.00 66.47  ? 273 PRO C CD   1 
ATOM   3528  N  N    . VAL C 1 67  ? 91.089  -10.722 32.234  1.00 71.66  ? 274 VAL C N    1 
ATOM   3529  C  CA   . VAL C 1 67  ? 91.246  -10.260 30.854  1.00 72.71  ? 274 VAL C CA   1 
ATOM   3530  C  C    . VAL C 1 67  ? 90.166  -9.241  30.490  1.00 67.42  ? 274 VAL C C    1 
ATOM   3531  O  O    . VAL C 1 67  ? 88.985  -9.422  30.813  1.00 66.00  ? 274 VAL C O    1 
ATOM   3532  C  CB   . VAL C 1 67  ? 91.195  -11.472 29.906  1.00 68.01  ? 274 VAL C CB   1 
ATOM   3533  C  CG1  . VAL C 1 67  ? 91.503  -11.059 28.480  1.00 68.39  ? 274 VAL C CG1  1 
ATOM   3534  C  CG2  . VAL C 1 67  ? 92.140  -12.556 30.400  1.00 67.57  ? 274 VAL C CG2  1 
ATOM   3535  N  N    . GLY C 1 68  ? 90.560  -8.181  29.773  1.00 58.28  ? 275 GLY C N    1 
ATOM   3536  C  CA   . GLY C 1 68  ? 89.613  -7.155  29.380  1.00 67.47  ? 275 GLY C CA   1 
ATOM   3537  C  C    . GLY C 1 68  ? 89.038  -7.338  27.971  1.00 70.66  ? 275 GLY C C    1 
ATOM   3538  O  O    . GLY C 1 68  ? 89.588  -8.046  27.130  1.00 72.28  ? 275 GLY C O    1 
ATOM   3539  N  N    . THR C 1 69  ? 87.910  -6.668  27.712  1.00 69.32  ? 276 THR C N    1 
ATOM   3540  C  CA   . THR C 1 69  ? 87.169  -6.849  26.465  1.00 70.63  ? 276 THR C CA   1 
ATOM   3541  C  C    . THR C 1 69  ? 86.957  -5.537  25.717  1.00 69.77  ? 276 THR C C    1 
ATOM   3542  O  O    . THR C 1 69  ? 86.073  -5.458  24.859  1.00 67.52  ? 276 THR C O    1 
ATOM   3543  C  CB   . THR C 1 69  ? 85.812  -7.526  26.725  1.00 68.90  ? 276 THR C CB   1 
ATOM   3544  O  OG1  . THR C 1 69  ? 84.976  -6.682  27.522  1.00 61.17  ? 276 THR C OG1  1 
ATOM   3545  C  CG2  . THR C 1 69  ? 85.985  -8.852  27.439  1.00 63.65  ? 276 THR C CG2  1 
ATOM   3546  N  N    . LYS C 1 70  ? 87.763  -4.513  26.015  1.00 74.34  ? 277 LYS C N    1 
ATOM   3547  C  CA   . LYS C 1 70  ? 87.566  -3.186  25.437  1.00 70.12  ? 277 LYS C CA   1 
ATOM   3548  C  C    . LYS C 1 70  ? 87.521  -3.236  23.911  1.00 71.34  ? 277 LYS C C    1 
ATOM   3549  O  O    . LYS C 1 70  ? 86.565  -2.754  23.290  1.00 67.23  ? 277 LYS C O    1 
ATOM   3550  N  N    . LYS C 1 71  ? 88.556  -3.824  23.290  1.00 69.99  ? 278 LYS C N    1 
ATOM   3551  C  CA   . LYS C 1 71  ? 88.658  -3.836  21.832  1.00 69.10  ? 278 LYS C CA   1 
ATOM   3552  C  C    . LYS C 1 71  ? 87.468  -4.539  21.185  1.00 71.15  ? 278 LYS C C    1 
ATOM   3553  O  O    . LYS C 1 71  ? 86.981  -4.099  20.136  1.00 68.89  ? 278 LYS C O    1 
ATOM   3554  N  N    . LEU C 1 72  ? 86.930  -5.584  21.814  1.00 74.22  ? 279 LEU C N    1 
ATOM   3555  C  CA   . LEU C 1 72  ? 85.756  -6.315  21.250  1.00 73.15  ? 279 LEU C CA   1 
ATOM   3556  C  C    . LEU C 1 72  ? 84.558  -5.373  21.109  1.00 70.60  ? 279 LEU C C    1 
ATOM   3557  O  O    . LEU C 1 72  ? 83.933  -5.364  20.043  1.00 70.40  ? 279 LEU C O    1 
ATOM   3558  C  CB   . LEU C 1 72  ? 85.414  -7.511  22.143  1.00 68.61  ? 279 LEU C CB   1 
ATOM   3559  C  CG   . LEU C 1 72  ? 84.314  -8.455  21.661  1.00 63.92  ? 279 LEU C CG   1 
ATOM   3560  C  CD1  . LEU C 1 72  ? 84.530  -8.881  20.221  1.00 64.76  ? 279 LEU C CD1  1 
ATOM   3561  C  CD2  . LEU C 1 72  ? 84.250  -9.680  22.551  1.00 65.64  ? 279 LEU C CD2  1 
ATOM   3562  N  N    . THR C 1 73  ? 84.245  -4.626  22.159  1.00 68.84  ? 280 THR C N    1 
ATOM   3563  C  CA   . THR C 1 73  ? 83.046  -3.753  22.115  1.00 72.29  ? 280 THR C CA   1 
ATOM   3564  C  C    . THR C 1 73  ? 83.261  -2.677  21.048  1.00 69.45  ? 280 THR C C    1 
ATOM   3565  O  O    . THR C 1 73  ? 82.299  -2.335  20.363  1.00 70.69  ? 280 THR C O    1 
ATOM   3566  C  CB   . THR C 1 73  ? 82.705  -3.245  23.522  1.00 70.28  ? 280 THR C CB   1 
ATOM   3567  O  OG1  . THR C 1 73  ? 83.893  -2.789  24.168  1.00 76.32  ? 280 THR C OG1  1 
ATOM   3568  C  CG2  . THR C 1 73  ? 82.048  -4.307  24.373  1.00 63.22  ? 280 THR C CG2  1 
ATOM   3569  N  N    . LYS C 1 74  ? 84.497  -2.217  20.877  1.00 73.67  ? 281 LYS C N    1 
ATOM   3570  C  CA   . LYS C 1 74  ? 84.810  -1.206  19.836  1.00 73.33  ? 281 LYS C CA   1 
ATOM   3571  C  C    . LYS C 1 74  ? 84.641  -1.831  18.453  1.00 73.00  ? 281 LYS C C    1 
ATOM   3572  O  O    . LYS C 1 74  ? 84.199  -1.120  17.546  1.00 71.42  ? 281 LYS C O    1 
ATOM   3573  C  CB   . LYS C 1 74  ? 86.238  -0.690  20.017  1.00 73.00  ? 281 LYS C CB   1 
ATOM   3574  C  CG   . LYS C 1 74  ? 86.436  0.793   19.743  1.00 69.57  ? 281 LYS C CG   1 
ATOM   3575  N  N    . SER C 1 75  ? 84.987  -3.112  18.308  1.00 75.27  ? 282 SER C N    1 
ATOM   3576  C  CA   . SER C 1 75  ? 84.859  -3.814  17.005  1.00 74.68  ? 282 SER C CA   1 
ATOM   3577  C  C    . SER C 1 75  ? 83.384  -3.908  16.617  1.00 72.58  ? 282 SER C C    1 
ATOM   3578  O  O    . SER C 1 75  ? 83.100  -3.936  15.414  1.00 77.59  ? 282 SER C O    1 
ATOM   3579  C  CB   . SER C 1 75  ? 85.516  -5.158  17.051  1.00 70.04  ? 282 SER C CB   1 
ATOM   3580  O  OG   . SER C 1 75  ? 84.656  -6.136  17.606  1.00 76.18  ? 282 SER C OG   1 
ATOM   3581  N  N    . PHE C 1 76  ? 82.493  -3.934  17.603  1.00 69.24  ? 283 PHE C N    1 
ATOM   3582  C  CA   . PHE C 1 76  ? 81.041  -3.968  17.326  1.00 66.84  ? 283 PHE C CA   1 
ATOM   3583  C  C    . PHE C 1 76  ? 80.607  -2.617  16.773  1.00 69.38  ? 283 PHE C C    1 
ATOM   3584  O  O    . PHE C 1 76  ? 79.579  -2.562  16.096  1.00 72.19  ? 283 PHE C O    1 
ATOM   3585  C  CB   . PHE C 1 76  ? 80.259  -4.225  18.610  1.00 68.41  ? 283 PHE C CB   1 
ATOM   3586  C  CG   . PHE C 1 76  ? 80.394  -5.589  19.234  1.00 67.83  ? 283 PHE C CG   1 
ATOM   3587  C  CD1  . PHE C 1 76  ? 81.031  -6.627  18.575  1.00 68.99  ? 283 PHE C CD1  1 
ATOM   3588  C  CD2  . PHE C 1 76  ? 79.863  -5.834  20.488  1.00 64.62  ? 283 PHE C CD2  1 
ATOM   3589  C  CE1  . PHE C 1 76  ? 81.145  -7.874  19.164  1.00 63.09  ? 283 PHE C CE1  1 
ATOM   3590  C  CE2  . PHE C 1 76  ? 79.974  -7.083  21.074  1.00 65.39  ? 283 PHE C CE2  1 
ATOM   3591  C  CZ   . PHE C 1 76  ? 80.613  -8.101  20.410  1.00 59.50  ? 283 PHE C CZ   1 
ATOM   3592  N  N    . GLY C 1 77  ? 81.384  -1.571  17.036  1.00 72.89  ? 284 GLY C N    1 
ATOM   3593  C  CA   . GLY C 1 77  ? 80.986  -0.210  16.636  1.00 72.67  ? 284 GLY C CA   1 
ATOM   3594  C  C    . GLY C 1 77  ? 80.264  0.445   17.787  1.00 72.82  ? 284 GLY C C    1 
ATOM   3595  O  O    . GLY C 1 77  ? 79.269  1.141   17.536  1.00 76.61  ? 284 GLY C O    1 
ATOM   3596  N  N    . TRP C 1 78  ? 80.770  0.259   19.001  1.00 72.77  ? 285 TRP C N    1 
ATOM   3597  C  CA   . TRP C 1 78  ? 80.044  0.737   20.198  1.00 77.15  ? 285 TRP C CA   1 
ATOM   3598  C  C    . TRP C 1 78  ? 80.788  1.818   20.968  1.00 77.45  ? 285 TRP C C    1 
ATOM   3599  O  O    . TRP C 1 78  ? 82.026  1.756   21.033  1.00 77.47  ? 285 TRP C O    1 
ATOM   3600  C  CB   . TRP C 1 78  ? 79.834  -0.445  21.145  1.00 74.27  ? 285 TRP C CB   1 
ATOM   3601  C  CG   . TRP C 1 78  ? 78.640  -1.315  20.922  1.00 71.95  ? 285 TRP C CG   1 
ATOM   3602  C  CD1  . TRP C 1 78  ? 77.757  -1.296  19.884  1.00 70.86  ? 285 TRP C CD1  1 
ATOM   3603  C  CD2  . TRP C 1 78  ? 78.204  -2.359  21.805  1.00 72.32  ? 285 TRP C CD2  1 
ATOM   3604  N  NE1  . TRP C 1 78  ? 76.798  -2.256  20.064  1.00 72.35  ? 285 TRP C NE1  1 
ATOM   3605  C  CE2  . TRP C 1 78  ? 77.046  -2.923  21.234  1.00 74.23  ? 285 TRP C CE2  1 
ATOM   3606  C  CE3  . TRP C 1 78  ? 78.676  -2.861  23.021  1.00 67.52  ? 285 TRP C CE3  1 
ATOM   3607  C  CZ2  . TRP C 1 78  ? 76.359  -3.970  21.844  1.00 72.30  ? 285 TRP C CZ2  1 
ATOM   3608  C  CZ3  . TRP C 1 78  ? 77.999  -3.897  23.620  1.00 68.36  ? 285 TRP C CZ3  1 
ATOM   3609  C  CH2  . TRP C 1 78  ? 76.857  -4.441  23.036  1.00 66.85  ? 285 TRP C CH2  1 
ATOM   3610  N  N    . GLU C 1 79  ? 80.050  2.773   21.521  1.00 78.11  ? 286 GLU C N    1 
ATOM   3611  C  CA   . GLU C 1 79  ? 80.611  3.747   22.445  1.00 78.36  ? 286 GLU C CA   1 
ATOM   3612  C  C    . GLU C 1 79  ? 80.648  3.139   23.844  1.00 77.12  ? 286 GLU C C    1 
ATOM   3613  O  O    . GLU C 1 79  ? 79.965  2.158   24.135  1.00 83.14  ? 286 GLU C O    1 
ATOM   3614  N  N    . THR C 1 80  ? 81.454  3.740   24.717  1.00 76.67  ? 287 THR C N    1 
ATOM   3615  C  CA   . THR C 1 80  ? 81.629  3.193   26.058  1.00 75.98  ? 287 THR C CA   1 
ATOM   3616  C  C    . THR C 1 80  ? 80.304  3.046   26.806  1.00 79.60  ? 287 THR C C    1 
ATOM   3617  O  O    . THR C 1 80  ? 80.147  2.106   27.599  1.00 78.64  ? 287 THR C O    1 
ATOM   3618  C  CB   . THR C 1 80  ? 82.604  4.070   26.853  1.00 80.45  ? 287 THR C CB   1 
ATOM   3619  O  OG1  . THR C 1 80  ? 83.632  4.550   25.975  1.00 86.52  ? 287 THR C OG1  1 
ATOM   3620  C  CG2  . THR C 1 80  ? 83.255  3.278   27.986  1.00 74.98  ? 287 THR C CG2  1 
ATOM   3621  N  N    . LEU C 1 81  ? 79.341  3.950   26.577  1.00 77.11  ? 288 LEU C N    1 
ATOM   3622  C  CA   . LEU C 1 81  ? 78.047  3.826   27.252  1.00 76.31  ? 288 LEU C CA   1 
ATOM   3623  C  C    . LEU C 1 81  ? 77.319  2.557   26.827  1.00 79.30  ? 288 LEU C C    1 
ATOM   3624  O  O    . LEU C 1 81  ? 76.583  1.960   27.627  1.00 72.17  ? 288 LEU C O    1 
ATOM   3625  C  CB   . LEU C 1 81  ? 77.165  5.045   26.971  1.00 64.85  ? 288 LEU C CB   1 
ATOM   3626  N  N    . ASP C 1 82  ? 77.506  2.143   25.566  1.00 78.77  ? 289 ASP C N    1 
ATOM   3627  C  CA   . ASP C 1 82  ? 76.876  0.929   25.066  1.00 72.29  ? 289 ASP C CA   1 
ATOM   3628  C  C    . ASP C 1 82  ? 77.287  -0.279  25.894  1.00 75.12  ? 289 ASP C C    1 
ATOM   3629  O  O    . ASP C 1 82  ? 76.551  -1.269  25.964  1.00 78.61  ? 289 ASP C O    1 
ATOM   3630  C  CB   . ASP C 1 82  ? 77.241  0.721   23.597  1.00 72.18  ? 289 ASP C CB   1 
ATOM   3631  C  CG   . ASP C 1 82  ? 76.552  1.707   22.682  1.00 76.31  ? 289 ASP C CG   1 
ATOM   3632  O  OD1  . ASP C 1 82  ? 75.306  1.791   22.733  1.00 82.79  ? 289 ASP C OD1  1 
ATOM   3633  O  OD2  . ASP C 1 82  ? 77.251  2.406   21.916  1.00 75.99  ? 289 ASP C OD2  1 
ATOM   3634  N  N    . SER C 1 83  ? 78.438  -0.205  26.547  1.00 69.82  ? 290 SER C N    1 
ATOM   3635  C  CA   . SER C 1 83  ? 78.966  -1.285  27.358  1.00 67.57  ? 290 SER C CA   1 
ATOM   3636  C  C    . SER C 1 83  ? 78.352  -1.331  28.768  1.00 68.23  ? 290 SER C C    1 
ATOM   3637  O  O    . SER C 1 83  ? 78.855  -2.047  29.643  1.00 66.76  ? 290 SER C O    1 
ATOM   3638  C  CB   . SER C 1 83  ? 80.489  -1.154  27.420  1.00 72.60  ? 290 SER C CB   1 
ATOM   3639  O  OG   . SER C 1 83  ? 81.083  -2.293  27.993  1.00 77.20  ? 290 SER C OG   1 
ATOM   3640  N  N    . PHE C 1 84  ? 77.263  -0.603  28.974  1.00 67.11  ? 291 PHE C N    1 
ATOM   3641  C  CA   . PHE C 1 84  ? 76.645  -0.539  30.320  1.00 68.18  ? 291 PHE C CA   1 
ATOM   3642  C  C    . PHE C 1 84  ? 75.181  -0.986  30.240  1.00 70.44  ? 291 PHE C C    1 
ATOM   3643  O  O    . PHE C 1 84  ? 74.484  -0.903  31.264  1.00 67.58  ? 291 PHE C O    1 
ATOM   3644  C  CB   . PHE C 1 84  ? 76.808  0.872   30.890  1.00 71.19  ? 291 PHE C CB   1 
ATOM   3645  C  CG   . PHE C 1 84  ? 78.107  1.124   31.610  1.00 65.52  ? 291 PHE C CG   1 
ATOM   3646  C  CD1  . PHE C 1 84  ? 79.268  1.396   30.908  1.00 68.56  ? 291 PHE C CD1  1 
ATOM   3647  C  CD2  . PHE C 1 84  ? 78.166  1.096   32.992  1.00 66.63  ? 291 PHE C CD2  1 
ATOM   3648  C  CE1  . PHE C 1 84  ? 80.463  1.622   31.571  1.00 69.85  ? 291 PHE C CE1  1 
ATOM   3649  C  CE2  . PHE C 1 84  ? 79.360  1.328   33.655  1.00 68.19  ? 291 PHE C CE2  1 
ATOM   3650  C  CZ   . PHE C 1 84  ? 80.506  1.590   32.944  1.00 70.44  ? 291 PHE C CZ   1 
ATOM   3651  N  N    . MET C 1 85  ? 74.730  -1.433  29.066  1.00 71.80  ? 292 MET C N    1 
ATOM   3652  C  CA   . MET C 1 85  ? 73.354  -1.982  28.934  1.00 70.12  ? 292 MET C CA   1 
ATOM   3653  C  C    . MET C 1 85  ? 73.399  -3.500  29.099  1.00 66.66  ? 292 MET C C    1 
ATOM   3654  O  O    . MET C 1 85  ? 74.339  -4.131  28.587  1.00 60.84  ? 292 MET C O    1 
ATOM   3655  C  CB   . MET C 1 85  ? 72.729  -1.656  27.578  1.00 65.83  ? 292 MET C CB   1 
ATOM   3656  C  CG   . MET C 1 85  ? 71.227  -1.846  27.556  1.00 63.40  ? 292 MET C CG   1 
ATOM   3657  S  SD   . MET C 1 85  ? 70.509  -1.687  25.909  1.00 85.97  ? 292 MET C SD   1 
ATOM   3658  C  CE   . MET C 1 85  ? 71.768  -0.715  25.082  1.00 68.34  ? 292 MET C CE   1 
ATOM   3659  N  N    . GLN C 1 86  ? 72.410  -4.050  29.797  1.00 67.19  ? 293 GLN C N    1 
ATOM   3660  C  CA   . GLN C 1 86  ? 72.334  -5.509  30.027  1.00 65.05  ? 293 GLN C CA   1 
ATOM   3661  C  C    . GLN C 1 86  ? 71.732  -6.187  28.796  1.00 65.73  ? 293 GLN C C    1 
ATOM   3662  O  O    . GLN C 1 86  ? 70.727  -5.686  28.288  1.00 72.27  ? 293 GLN C O    1 
ATOM   3663  C  CB   . GLN C 1 86  ? 71.477  -5.726  31.265  1.00 60.92  ? 293 GLN C CB   1 
ATOM   3664  N  N    . HIS C 1 87  ? 72.337  -7.277  28.330  1.00 62.56  ? 294 HIS C N    1 
ATOM   3665  C  CA   . HIS C 1 87  ? 71.850  -7.950  27.133  1.00 60.17  ? 294 HIS C CA   1 
ATOM   3666  C  C    . HIS C 1 87  ? 71.640  -9.448  27.349  1.00 61.49  ? 294 HIS C C    1 
ATOM   3667  O  O    . HIS C 1 87  ? 71.987  -10.021 28.388  1.00 59.11  ? 294 HIS C O    1 
ATOM   3668  C  CB   . HIS C 1 87  ? 72.802  -7.730  25.956  1.00 61.14  ? 294 HIS C CB   1 
ATOM   3669  C  CG   . HIS C 1 87  ? 72.599  -6.423  25.263  1.00 67.13  ? 294 HIS C CG   1 
ATOM   3670  N  ND1  . HIS C 1 87  ? 73.584  -5.460  25.188  1.00 67.02  ? 294 HIS C ND1  1 
ATOM   3671  C  CD2  . HIS C 1 87  ? 71.517  -5.911  24.628  1.00 63.45  ? 294 HIS C CD2  1 
ATOM   3672  C  CE1  . HIS C 1 87  ? 73.116  -4.412  24.533  1.00 70.73  ? 294 HIS C CE1  1 
ATOM   3673  N  NE2  . HIS C 1 87  ? 71.865  -4.661  24.182  1.00 66.14  ? 294 HIS C NE2  1 
ATOM   3674  N  N    . ASP C 1 88  ? 71.075  -10.076 26.313  1.00 62.74  ? 295 ASP C N    1 
ATOM   3675  C  CA   . ASP C 1 88  ? 70.712  -11.490 26.315  1.00 53.83  ? 295 ASP C CA   1 
ATOM   3676  C  C    . ASP C 1 88  ? 71.861  -12.309 25.747  1.00 52.22  ? 295 ASP C C    1 
ATOM   3677  O  O    . ASP C 1 88  ? 72.395  -11.999 24.678  1.00 52.04  ? 295 ASP C O    1 
ATOM   3678  C  CB   . ASP C 1 88  ? 69.437  -11.706 25.493  1.00 53.36  ? 295 ASP C CB   1 
ATOM   3679  C  CG   . ASP C 1 88  ? 69.066  -13.170 25.341  1.00 58.66  ? 295 ASP C CG   1 
ATOM   3680  O  OD1  . ASP C 1 88  ? 69.819  -13.910 24.641  1.00 54.81  ? 295 ASP C OD1  1 
ATOM   3681  O  OD2  . ASP C 1 88  ? 67.999  -13.571 25.897  1.00 53.05  ? 295 ASP C OD2  1 
ATOM   3682  N  N    . VAL C 1 89  ? 72.231  -13.370 26.448  1.00 56.58  ? 296 VAL C N    1 
ATOM   3683  C  CA   . VAL C 1 89  ? 73.445  -14.067 26.050  1.00 56.79  ? 296 VAL C CA   1 
ATOM   3684  C  C    . VAL C 1 89  ? 73.225  -14.832 24.744  1.00 54.50  ? 296 VAL C C    1 
ATOM   3685  O  O    . VAL C 1 89  ? 74.073  -14.804 23.846  1.00 52.48  ? 296 VAL C O    1 
ATOM   3686  C  CB   . VAL C 1 89  ? 73.949  -14.963 27.197  1.00 52.38  ? 296 VAL C CB   1 
ATOM   3687  C  CG1  . VAL C 1 89  ? 72.980  -16.086 27.510  1.00 51.48  ? 296 VAL C CG1  1 
ATOM   3688  C  CG2  . VAL C 1 89  ? 75.325  -15.494 26.858  1.00 57.86  ? 296 VAL C CG2  1 
ATOM   3689  N  N    . GLN C 1 90  ? 72.068  -15.454 24.566  1.00 54.91  ? 297 GLN C N    1 
ATOM   3690  C  CA   . GLN C 1 90  ? 71.799  -16.213 23.324  1.00 52.87  ? 297 GLN C CA   1 
ATOM   3691  C  C    . GLN C 1 90  ? 71.681  -15.244 22.145  1.00 53.75  ? 297 GLN C C    1 
ATOM   3692  O  O    . GLN C 1 90  ? 72.088  -15.617 21.046  1.00 50.16  ? 297 GLN C O    1 
ATOM   3693  C  CB   . GLN C 1 90  ? 70.559  -17.085 23.499  1.00 54.39  ? 297 GLN C CB   1 
ATOM   3694  C  CG   . GLN C 1 90  ? 70.354  -18.073 22.369  1.00 50.12  ? 297 GLN C CG   1 
ATOM   3695  C  CD   . GLN C 1 90  ? 69.341  -17.512 21.409  1.00 52.24  ? 297 GLN C CD   1 
ATOM   3696  O  OE1  . GLN C 1 90  ? 68.597  -16.601 21.737  1.00 50.59  ? 297 GLN C OE1  1 
ATOM   3697  N  NE2  . GLN C 1 90  ? 69.290  -18.064 20.217  1.00 55.65  ? 297 GLN C NE2  1 
ATOM   3698  N  N    . GLU C 1 91  ? 71.145  -14.047 22.369  1.00 52.99  ? 298 GLU C N    1 
ATOM   3699  C  CA   . GLU C 1 91  ? 71.126  -13.088 21.266  1.00 52.93  ? 298 GLU C CA   1 
ATOM   3700  C  C    . GLU C 1 91  ? 72.539  -12.727 20.845  1.00 50.19  ? 298 GLU C C    1 
ATOM   3701  O  O    . GLU C 1 91  ? 72.823  -12.583 19.655  1.00 50.72  ? 298 GLU C O    1 
ATOM   3702  C  CB   . GLU C 1 91  ? 70.338  -11.827 21.652  1.00 57.85  ? 298 GLU C CB   1 
ATOM   3703  C  CG   . GLU C 1 91  ? 70.375  -10.686 20.598  1.00 54.08  ? 298 GLU C CG   1 
ATOM   3704  C  CD   . GLU C 1 91  ? 69.334  -9.588  20.845  1.00 54.32  ? 298 GLU C CD   1 
ATOM   3705  O  OE1  . GLU C 1 91  ? 68.945  -8.882  19.887  1.00 57.74  ? 298 GLU C OE1  1 
ATOM   3706  O  OE2  . GLU C 1 91  ? 68.885  -9.426  21.996  1.00 58.69  ? 298 GLU C OE2  1 
ATOM   3707  N  N    . LEU C 1 92  ? 73.447  -12.595 21.799  1.00 55.37  ? 299 LEU C N    1 
ATOM   3708  C  CA   . LEU C 1 92  ? 74.824  -12.321 21.418  1.00 56.48  ? 299 LEU C CA   1 
ATOM   3709  C  C    . LEU C 1 92  ? 75.418  -13.504 20.660  1.00 54.43  ? 299 LEU C C    1 
ATOM   3710  O  O    . LEU C 1 92  ? 76.164  -13.317 19.683  1.00 55.56  ? 299 LEU C O    1 
ATOM   3711  C  CB   . LEU C 1 92  ? 75.653  -11.978 22.656  1.00 55.44  ? 299 LEU C CB   1 
ATOM   3712  C  CG   . LEU C 1 92  ? 77.146  -11.769 22.416  1.00 54.22  ? 299 LEU C CG   1 
ATOM   3713  C  CD1  . LEU C 1 92  ? 77.405  -10.568 21.500  1.00 53.82  ? 299 LEU C CD1  1 
ATOM   3714  C  CD2  . LEU C 1 92  ? 77.853  -11.642 23.769  1.00 54.65  ? 299 LEU C CD2  1 
ATOM   3715  N  N    . CYS C 1 93  ? 75.057  -14.728 21.066  1.00 52.91  ? 300 CYS C N    1 
ATOM   3716  C  CA   . CYS C 1 93  ? 75.610  -15.921 20.432  1.00 49.85  ? 300 CYS C CA   1 
ATOM   3717  C  C    . CYS C 1 93  ? 75.191  -16.030 18.972  1.00 52.69  ? 300 CYS C C    1 
ATOM   3718  O  O    . CYS C 1 93  ? 76.010  -16.379 18.108  1.00 54.03  ? 300 CYS C O    1 
ATOM   3719  C  CB   . CYS C 1 93  ? 75.201  -17.169 21.195  1.00 41.18  ? 300 CYS C CB   1 
ATOM   3720  S  SG   . CYS C 1 93  ? 76.111  -18.617 20.561  1.00 54.23  ? 300 CYS C SG   1 
ATOM   3721  N  N    . ARG C 1 94  ? 73.927  -15.727 18.672  1.00 47.99  ? 301 ARG C N    1 
ATOM   3722  C  CA   . ARG C 1 94  ? 73.477  -15.761 17.286  1.00 50.82  ? 301 ARG C CA   1 
ATOM   3723  C  C    . ARG C 1 94  ? 74.216  -14.727 16.436  1.00 54.57  ? 301 ARG C C    1 
ATOM   3724  O  O    . ARG C 1 94  ? 74.733  -15.044 15.357  1.00 53.32  ? 301 ARG C O    1 
ATOM   3725  C  CB   . ARG C 1 94  ? 71.963  -15.549 17.218  1.00 48.59  ? 301 ARG C CB   1 
ATOM   3726  C  CG   . ARG C 1 94  ? 71.130  -16.636 17.941  1.00 53.88  ? 301 ARG C CG   1 
ATOM   3727  C  CD   . ARG C 1 94  ? 70.907  -17.885 17.108  1.00 43.93  ? 301 ARG C CD   1 
ATOM   3728  N  NE   . ARG C 1 94  ? 72.168  -18.470 16.667  1.00 49.13  ? 301 ARG C NE   1 
ATOM   3729  C  CZ   . ARG C 1 94  ? 72.926  -19.256 17.433  1.00 51.31  ? 301 ARG C CZ   1 
ATOM   3730  N  NH1  . ARG C 1 94  ? 72.540  -19.578 18.675  1.00 51.17  ? 301 ARG C NH1  1 
ATOM   3731  N  NH2  . ARG C 1 94  ? 74.065  -19.733 16.956  1.00 51.81  ? 301 ARG C NH2  1 
ATOM   3732  N  N    . VAL C 1 95  ? 74.298  -13.483 16.904  1.00 52.75  ? 302 VAL C N    1 
ATOM   3733  C  CA   . VAL C 1 95  ? 74.952  -12.482 16.074  1.00 45.74  ? 302 VAL C CA   1 
ATOM   3734  C  C    . VAL C 1 95  ? 76.457  -12.706 16.051  1.00 51.68  ? 302 VAL C C    1 
ATOM   3735  O  O    . VAL C 1 95  ? 77.098  -12.544 15.011  1.00 54.75  ? 302 VAL C O    1 
ATOM   3736  C  CB   . VAL C 1 95  ? 74.587  -11.062 16.541  1.00 61.63  ? 302 VAL C CB   1 
ATOM   3737  C  CG1  . VAL C 1 95  ? 74.988  -10.048 15.491  1.00 60.65  ? 302 VAL C CG1  1 
ATOM   3738  C  CG2  . VAL C 1 95  ? 73.095  -10.950 16.810  1.00 53.29  ? 302 VAL C CG2  1 
ATOM   3739  N  N    . LEU C 1 96  ? 77.050  -13.122 17.172  1.00 53.57  ? 303 LEU C N    1 
ATOM   3740  C  CA   . LEU C 1 96  ? 78.500  -13.292 17.174  1.00 55.00  ? 303 LEU C CA   1 
ATOM   3741  C  C    . LEU C 1 96  ? 78.932  -14.415 16.237  1.00 53.08  ? 303 LEU C C    1 
ATOM   3742  O  O    . LEU C 1 96  ? 79.803  -14.213 15.384  1.00 58.62  ? 303 LEU C O    1 
ATOM   3743  C  CB   . LEU C 1 96  ? 79.028  -13.530 18.594  1.00 51.04  ? 303 LEU C CB   1 
ATOM   3744  C  CG   . LEU C 1 96  ? 80.548  -13.764 18.686  1.00 48.80  ? 303 LEU C CG   1 
ATOM   3745  C  CD1  . LEU C 1 96  ? 81.296  -12.511 18.313  1.00 61.87  ? 303 LEU C CD1  1 
ATOM   3746  C  CD2  . LEU C 1 96  ? 80.971  -14.203 20.067  1.00 49.23  ? 303 LEU C CD2  1 
ATOM   3747  N  N    . LEU C 1 97  ? 78.339  -15.604 16.369  1.00 54.93  ? 304 LEU C N    1 
ATOM   3748  C  CA   . LEU C 1 97  ? 78.776  -16.729 15.541  1.00 52.57  ? 304 LEU C CA   1 
ATOM   3749  C  C    . LEU C 1 97  ? 78.560  -16.442 14.062  1.00 53.33  ? 304 LEU C C    1 
ATOM   3750  O  O    . LEU C 1 97  ? 79.446  -16.709 13.237  1.00 54.58  ? 304 LEU C O    1 
ATOM   3751  C  CB   . LEU C 1 97  ? 78.045  -18.008 15.940  1.00 49.08  ? 304 LEU C CB   1 
ATOM   3752  C  CG   . LEU C 1 97  ? 78.399  -18.588 17.304  1.00 53.13  ? 304 LEU C CG   1 
ATOM   3753  C  CD1  . LEU C 1 97  ? 77.621  -19.885 17.577  1.00 45.69  ? 304 LEU C CD1  1 
ATOM   3754  C  CD2  . LEU C 1 97  ? 79.917  -18.806 17.438  1.00 47.42  ? 304 LEU C CD2  1 
ATOM   3755  N  N    . ASP C 1 98  ? 77.395  -15.883 13.709  1.00 48.22  ? 305 ASP C N    1 
ATOM   3756  C  CA   . ASP C 1 98  ? 77.123  -15.540 12.314  1.00 52.01  ? 305 ASP C CA   1 
ATOM   3757  C  C    . ASP C 1 98  ? 78.188  -14.608 11.757  1.00 57.82  ? 305 ASP C C    1 
ATOM   3758  O  O    . ASP C 1 98  ? 78.707  -14.832 10.657  1.00 58.62  ? 305 ASP C O    1 
ATOM   3759  C  CB   . ASP C 1 98  ? 75.741  -14.897 12.161  1.00 44.42  ? 305 ASP C CB   1 
ATOM   3760  C  CG   . ASP C 1 98  ? 75.483  -14.410 10.719  1.00 53.78  ? 305 ASP C CG   1 
ATOM   3761  O  OD1  . ASP C 1 98  ? 75.240  -15.248 9.827   1.00 53.87  ? 305 ASP C OD1  1 
ATOM   3762  O  OD2  . ASP C 1 98  ? 75.536  -13.189 10.461  1.00 56.66  ? 305 ASP C OD2  1 
ATOM   3763  N  N    . ASN C 1 99  ? 78.520  -13.546 12.504  1.00 57.28  ? 306 ASN C N    1 
ATOM   3764  C  CA   . ASN C 1 99  ? 79.582  -12.638 12.079  1.00 57.87  ? 306 ASN C CA   1 
ATOM   3765  C  C    . ASN C 1 99  ? 80.889  -13.396 11.848  1.00 56.98  ? 306 ASN C C    1 
ATOM   3766  O  O    . ASN C 1 99  ? 81.519  -13.262 10.795  1.00 61.17  ? 306 ASN C O    1 
ATOM   3767  C  CB   . ASN C 1 99  ? 79.749  -11.518 13.115  1.00 59.16  ? 306 ASN C CB   1 
ATOM   3768  C  CG   . ASN C 1 99  ? 80.904  -10.574 12.797  1.00 63.65  ? 306 ASN C CG   1 
ATOM   3769  O  OD1  . ASN C 1 99  ? 82.075  -10.923 12.983  1.00 65.25  ? 306 ASN C OD1  1 
ATOM   3770  N  ND2  . ASN C 1 99  ? 80.580  -9.366  12.347  1.00 59.67  ? 306 ASN C ND2  1 
ATOM   3771  N  N    . VAL C 1 100 ? 81.297  -14.218 12.813  1.00 57.38  ? 307 VAL C N    1 
ATOM   3772  C  CA   . VAL C 1 100 ? 82.523  -15.001 12.659  1.00 59.33  ? 307 VAL C CA   1 
ATOM   3773  C  C    . VAL C 1 100 ? 82.400  -15.976 11.494  1.00 60.86  ? 307 VAL C C    1 
ATOM   3774  O  O    . VAL C 1 100 ? 83.348  -16.161 10.719  1.00 62.50  ? 307 VAL C O    1 
ATOM   3775  C  CB   . VAL C 1 100 ? 82.859  -15.742 13.967  1.00 57.99  ? 307 VAL C CB   1 
ATOM   3776  C  CG1  . VAL C 1 100 ? 84.103  -16.577 13.783  1.00 60.12  ? 307 VAL C CG1  1 
ATOM   3777  C  CG2  . VAL C 1 100 ? 83.035  -14.759 15.113  1.00 60.85  ? 307 VAL C CG2  1 
ATOM   3778  N  N    . GLU C 1 101 ? 81.235  -16.621 11.359  1.00 63.24  ? 308 GLU C N    1 
ATOM   3779  C  CA   . GLU C 1 101 ? 81.033  -17.612 10.300  1.00 62.95  ? 308 GLU C CA   1 
ATOM   3780  C  C    . GLU C 1 101 ? 81.268  -17.006 8.917   1.00 62.02  ? 308 GLU C C    1 
ATOM   3781  O  O    . GLU C 1 101 ? 81.995  -17.576 8.095   1.00 61.20  ? 308 GLU C O    1 
ATOM   3782  C  CB   . GLU C 1 101 ? 79.627  -18.210 10.421  1.00 60.97  ? 308 GLU C CB   1 
ATOM   3783  C  CG   . GLU C 1 101 ? 79.100  -18.976 9.213   1.00 56.65  ? 308 GLU C CG   1 
ATOM   3784  C  CD   . GLU C 1 101 ? 77.945  -19.932 9.593   1.00 65.83  ? 308 GLU C CD   1 
ATOM   3785  O  OE1  . GLU C 1 101 ? 77.101  -19.578 10.462  1.00 58.02  ? 308 GLU C OE1  1 
ATOM   3786  O  OE2  . GLU C 1 101 ? 77.895  -21.050 9.023   1.00 67.74  ? 308 GLU C OE2  1 
ATOM   3787  N  N    . ASN C 1 102 ? 80.686  -15.834 8.651   1.00 60.78  ? 309 ASN C N    1 
ATOM   3788  C  CA   . ASN C 1 102 ? 81.012  -15.128 7.415   1.00 62.30  ? 309 ASN C CA   1 
ATOM   3789  C  C    . ASN C 1 102 ? 82.508  -14.853 7.318   1.00 64.15  ? 309 ASN C C    1 
ATOM   3790  O  O    . ASN C 1 102 ? 83.157  -15.245 6.343   1.00 69.57  ? 309 ASN C O    1 
ATOM   3791  C  CB   . ASN C 1 102 ? 80.205  -13.838 7.318   1.00 55.41  ? 309 ASN C CB   1 
ATOM   3792  C  CG   . ASN C 1 102 ? 78.685  -14.093 7.406   1.00 74.88  ? 309 ASN C CG   1 
ATOM   3793  O  OD1  . ASN C 1 102 ? 78.222  -15.250 7.352   1.00 69.25  ? 309 ASN C OD1  1 
ATOM   3794  N  ND2  . ASN C 1 102 ? 77.903  -13.011 7.538   1.00 67.86  ? 309 ASN C ND2  1 
ATOM   3795  N  N    . LYS C 1 103 ? 83.091  -14.231 8.344   1.00 63.56  ? 310 LYS C N    1 
ATOM   3796  C  CA   . LYS C 1 103 ? 84.489  -13.815 8.244   1.00 66.95  ? 310 LYS C CA   1 
ATOM   3797  C  C    . LYS C 1 103 ? 85.439  -14.989 8.036   1.00 64.79  ? 310 LYS C C    1 
ATOM   3798  O  O    . LYS C 1 103 ? 86.586  -14.776 7.628   1.00 66.71  ? 310 LYS C O    1 
ATOM   3799  C  CB   . LYS C 1 103 ? 84.912  -13.024 9.487   1.00 59.36  ? 310 LYS C CB   1 
ATOM   3800  N  N    . MET C 1 104 ? 85.008  -16.213 8.319   1.00 62.33  ? 311 MET C N    1 
ATOM   3801  C  CA   . MET C 1 104 ? 85.810  -17.381 7.986   1.00 65.69  ? 311 MET C CA   1 
ATOM   3802  C  C    . MET C 1 104 ? 85.585  -17.857 6.551   1.00 68.62  ? 311 MET C C    1 
ATOM   3803  O  O    . MET C 1 104 ? 86.226  -18.825 6.125   1.00 67.90  ? 311 MET C O    1 
ATOM   3804  C  CB   . MET C 1 104 ? 85.510  -18.539 8.948   1.00 61.86  ? 311 MET C CB   1 
ATOM   3805  C  CG   . MET C 1 104 ? 85.770  -18.264 10.403  1.00 62.58  ? 311 MET C CG   1 
ATOM   3806  S  SD   . MET C 1 104 ? 85.824  -19.821 11.311  1.00 71.80  ? 311 MET C SD   1 
ATOM   3807  C  CE   . MET C 1 104 ? 86.710  -19.349 12.788  1.00 58.31  ? 311 MET C CE   1 
ATOM   3808  N  N    . LYS C 1 105 ? 84.673  -17.234 5.807   1.00 63.71  ? 312 LYS C N    1 
ATOM   3809  C  CA   . LYS C 1 105 ? 84.406  -17.690 4.451   1.00 72.35  ? 312 LYS C CA   1 
ATOM   3810  C  C    . LYS C 1 105 ? 85.529  -17.262 3.514   1.00 74.77  ? 312 LYS C C    1 
ATOM   3811  O  O    . LYS C 1 105 ? 86.011  -16.127 3.565   1.00 72.03  ? 312 LYS C O    1 
ATOM   3812  C  CB   . LYS C 1 105 ? 83.068  -17.149 3.952   1.00 71.39  ? 312 LYS C CB   1 
ATOM   3813  C  CG   . LYS C 1 105 ? 81.893  -18.034 4.282   1.00 72.42  ? 312 LYS C CG   1 
ATOM   3814  C  CD   . LYS C 1 105 ? 80.616  -17.451 3.724   1.00 69.45  ? 312 LYS C CD   1 
ATOM   3815  C  CE   . LYS C 1 105 ? 79.399  -18.230 4.198   1.00 69.46  ? 312 LYS C CE   1 
ATOM   3816  N  NZ   . LYS C 1 105 ? 78.131  -17.586 3.735   1.00 77.27  ? 312 LYS C NZ   1 
ATOM   3817  N  N    . GLY C 1 106 ? 85.937  -18.182 2.645   1.00 76.05  ? 313 GLY C N    1 
ATOM   3818  C  CA   . GLY C 1 106 ? 87.066  -17.926 1.779   1.00 72.91  ? 313 GLY C CA   1 
ATOM   3819  C  C    . GLY C 1 106 ? 88.410  -18.112 2.438   1.00 75.36  ? 313 GLY C C    1 
ATOM   3820  O  O    . GLY C 1 106 ? 89.392  -17.526 1.973   1.00 79.22  ? 313 GLY C O    1 
ATOM   3821  N  N    . THR C 1 107 ? 88.419  -18.850 3.550   1.00 72.04  ? 314 THR C N    1 
ATOM   3822  C  CA   . THR C 1 107 ? 89.659  -19.095 4.324   1.00 64.56  ? 314 THR C CA   1 
ATOM   3823  C  C    . THR C 1 107 ? 89.786  -20.594 4.596   1.00 67.15  ? 314 THR C C    1 
ATOM   3824  O  O    . THR C 1 107 ? 88.856  -21.337 4.256   1.00 70.45  ? 314 THR C O    1 
ATOM   3825  C  CB   . THR C 1 107 ? 89.657  -18.297 5.633   1.00 66.96  ? 314 THR C CB   1 
ATOM   3826  O  OG1  . THR C 1 107 ? 88.851  -18.996 6.577   1.00 69.82  ? 314 THR C OG1  1 
ATOM   3827  C  CG2  . THR C 1 107 ? 89.139  -16.881 5.498   1.00 62.35  ? 314 THR C CG2  1 
ATOM   3828  N  N    . CYS C 1 108 ? 90.876  -21.016 5.232   1.00 70.15  ? 315 CYS C N    1 
ATOM   3829  C  CA   . CYS C 1 108 ? 91.126  -22.459 5.498   1.00 70.84  ? 315 CYS C CA   1 
ATOM   3830  C  C    . CYS C 1 108 ? 90.232  -22.966 6.627   1.00 72.83  ? 315 CYS C C    1 
ATOM   3831  O  O    . CYS C 1 108 ? 90.307  -24.166 6.931   1.00 75.53  ? 315 CYS C O    1 
ATOM   3832  C  CB   . CYS C 1 108 ? 92.575  -22.689 5.904   1.00 75.67  ? 315 CYS C CB   1 
ATOM   3833  S  SG   . CYS C 1 108 ? 93.098  -21.746 7.361   1.00 93.41  ? 315 CYS C SG   1 
ATOM   3834  N  N    . VAL C 1 109 ? 89.424  -22.081 7.206   1.00 73.28  ? 316 VAL C N    1 
ATOM   3835  C  CA   . VAL C 1 109 ? 88.562  -22.477 8.355   1.00 73.68  ? 316 VAL C CA   1 
ATOM   3836  C  C    . VAL C 1 109 ? 87.094  -22.250 7.991   1.00 68.56  ? 316 VAL C C    1 
ATOM   3837  O  O    . VAL C 1 109 ? 86.260  -22.302 8.897   1.00 63.45  ? 316 VAL C O    1 
ATOM   3838  C  CB   . VAL C 1 109 ? 88.988  -21.754 9.650   1.00 70.02  ? 316 VAL C CB   1 
ATOM   3839  C  CG1  . VAL C 1 109 ? 90.197  -22.420 10.281  1.00 66.78  ? 316 VAL C CG1  1 
ATOM   3840  C  CG2  . VAL C 1 109 ? 89.257  -20.276 9.439   1.00 68.45  ? 316 VAL C CG2  1 
ATOM   3841  N  N    . GLU C 1 110 ? 86.788  -22.025 6.712   1.00 68.59  ? 317 GLU C N    1 
ATOM   3842  C  CA   . GLU C 1 110 ? 85.399  -21.906 6.294   1.00 65.05  ? 317 GLU C CA   1 
ATOM   3843  C  C    . GLU C 1 110 ? 84.628  -23.147 6.707   1.00 66.52  ? 317 GLU C C    1 
ATOM   3844  O  O    . GLU C 1 110 ? 85.119  -24.272 6.561   1.00 62.90  ? 317 GLU C O    1 
ATOM   3845  C  CB   . GLU C 1 110 ? 85.316  -21.728 4.790   1.00 69.73  ? 317 GLU C CB   1 
ATOM   3846  C  CG   . GLU C 1 110 ? 83.910  -21.751 4.247   1.00 70.15  ? 317 GLU C CG   1 
ATOM   3847  C  CD   . GLU C 1 110 ? 83.819  -21.078 2.900   1.00 70.21  ? 317 GLU C CD   1 
ATOM   3848  O  OE1  . GLU C 1 110 ? 82.694  -20.925 2.392   1.00 78.38  ? 317 GLU C OE1  1 
ATOM   3849  O  OE2  . GLU C 1 110 ? 84.875  -20.688 2.354   1.00 71.59  ? 317 GLU C OE2  1 
ATOM   3850  N  N    . GLY C 1 111 ? 83.438  -22.934 7.283   1.00 58.90  ? 318 GLY C N    1 
ATOM   3851  C  CA   . GLY C 1 111 ? 82.576  -24.031 7.681   1.00 50.69  ? 318 GLY C CA   1 
ATOM   3852  C  C    . GLY C 1 111 ? 82.804  -24.610 9.065   1.00 55.28  ? 318 GLY C C    1 
ATOM   3853  O  O    . GLY C 1 111 ? 82.131  -25.582 9.427   1.00 54.42  ? 318 GLY C O    1 
ATOM   3854  N  N    . THR C 1 112 ? 83.658  -24.006 9.882   1.00 59.03  ? 319 THR C N    1 
ATOM   3855  C  CA   . THR C 1 112 ? 83.947  -24.599 11.212  1.00 54.04  ? 319 THR C CA   1 
ATOM   3856  C  C    . THR C 1 112 ? 82.710  -24.464 12.104  1.00 50.47  ? 319 THR C C    1 
ATOM   3857  O  O    . THR C 1 112 ? 82.303  -25.465 12.691  1.00 51.21  ? 319 THR C O    1 
ATOM   3858  C  CB   . THR C 1 112 ? 85.185  -23.958 11.848  1.00 60.32  ? 319 THR C CB   1 
ATOM   3859  O  OG1  . THR C 1 112 ? 86.256  -24.005 10.908  1.00 62.41  ? 319 THR C OG1  1 
ATOM   3860  C  CG2  . THR C 1 112 ? 85.609  -24.647 13.126  1.00 54.17  ? 319 THR C CG2  1 
ATOM   3861  N  N    . ILE C 1 113 ? 82.151  -23.262 12.194  1.00 51.60  ? 320 ILE C N    1 
ATOM   3862  C  CA   . ILE C 1 113 ? 80.935  -23.006 13.018  1.00 50.35  ? 320 ILE C CA   1 
ATOM   3863  C  C    . ILE C 1 113 ? 79.804  -23.948 12.581  1.00 55.22  ? 320 ILE C C    1 
ATOM   3864  O  O    . ILE C 1 113 ? 79.263  -24.604 13.465  1.00 51.92  ? 320 ILE C O    1 
ATOM   3865  C  CB   . ILE C 1 113 ? 80.569  -21.503 12.997  1.00 52.11  ? 320 ILE C CB   1 
ATOM   3866  C  CG1  . ILE C 1 113 ? 81.480  -20.700 13.923  1.00 56.84  ? 320 ILE C CG1  1 
ATOM   3867  C  CG2  . ILE C 1 113 ? 79.106  -21.262 13.332  1.00 56.71  ? 320 ILE C CG2  1 
ATOM   3868  C  CD1  . ILE C 1 113 ? 82.395  -19.759 13.199  1.00 56.08  ? 320 ILE C CD1  1 
ATOM   3869  N  N    . PRO C 1 114 ? 79.410  -24.083 11.293  1.00 52.43  ? 321 PRO C N    1 
ATOM   3870  C  CA   . PRO C 1 114 ? 78.394  -25.065 10.915  1.00 52.47  ? 321 PRO C CA   1 
ATOM   3871  C  C    . PRO C 1 114 ? 78.762  -26.520 11.256  1.00 48.01  ? 321 PRO C C    1 
ATOM   3872  O  O    . PRO C 1 114 ? 77.906  -27.244 11.671  1.00 49.31  ? 321 PRO C O    1 
ATOM   3873  C  CB   . PRO C 1 114 ? 78.195  -24.893 9.404   1.00 54.83  ? 321 PRO C CB   1 
ATOM   3874  C  CG   . PRO C 1 114 ? 79.276  -23.981 8.934   1.00 54.72  ? 321 PRO C CG   1 
ATOM   3875  C  CD   . PRO C 1 114 ? 79.788  -23.255 10.153  1.00 54.61  ? 321 PRO C CD   1 
ATOM   3876  N  N    . LYS C 1 115 ? 80.025  -26.900 11.103  1.00 51.26  ? 322 LYS C N    1 
ATOM   3877  C  CA   . LYS C 1 115 ? 80.464  -28.287 11.380  1.00 52.24  ? 322 LYS C CA   1 
ATOM   3878  C  C    . LYS C 1 115 ? 80.292  -28.576 12.864  1.00 54.18  ? 322 LYS C C    1 
ATOM   3879  O  O    . LYS C 1 115 ? 80.038  -29.723 13.204  1.00 51.86  ? 322 LYS C O    1 
ATOM   3880  C  CB   . LYS C 1 115 ? 81.925  -28.467 10.963  1.00 59.09  ? 322 LYS C CB   1 
ATOM   3881  C  CG   . LYS C 1 115 ? 82.512  -29.862 11.121  1.00 52.98  ? 322 LYS C CG   1 
ATOM   3882  N  N    . LEU C 1 116 ? 80.358  -27.546 13.689  1.00 60.62  ? 323 LEU C N    1 
ATOM   3883  C  CA   . LEU C 1 116 ? 80.293  -27.740 15.152  1.00 53.29  ? 323 LEU C CA   1 
ATOM   3884  C  C    . LEU C 1 116 ? 78.900  -27.448 15.696  1.00 51.59  ? 323 LEU C C    1 
ATOM   3885  O  O    . LEU C 1 116 ? 78.501  -28.144 16.622  1.00 45.46  ? 323 LEU C O    1 
ATOM   3886  C  CB   . LEU C 1 116 ? 81.302  -26.765 15.766  1.00 52.32  ? 323 LEU C CB   1 
ATOM   3887  C  CG   . LEU C 1 116 ? 82.528  -27.373 16.439  1.00 56.44  ? 323 LEU C CG   1 
ATOM   3888  C  CD1  . LEU C 1 116 ? 83.015  -28.601 15.693  1.00 51.43  ? 323 LEU C CD1  1 
ATOM   3889  C  CD2  . LEU C 1 116 ? 83.635  -26.341 16.532  1.00 56.58  ? 323 LEU C CD2  1 
ATOM   3890  N  N    . PHE C 1 117 ? 78.157  -26.522 15.091  1.00 49.81  ? 324 PHE C N    1 
ATOM   3891  C  CA   . PHE C 1 117 ? 76.925  -26.079 15.734  1.00 48.02  ? 324 PHE C CA   1 
ATOM   3892  C  C    . PHE C 1 117 ? 75.640  -26.323 14.942  1.00 50.75  ? 324 PHE C C    1 
ATOM   3893  O  O    . PHE C 1 117 ? 74.550  -26.181 15.521  1.00 45.07  ? 324 PHE C O    1 
ATOM   3894  C  CB   . PHE C 1 117 ? 76.994  -24.575 16.046  1.00 48.40  ? 324 PHE C CB   1 
ATOM   3895  C  CG   . PHE C 1 117 ? 78.141  -24.154 16.958  1.00 51.64  ? 324 PHE C CG   1 
ATOM   3896  C  CD1  . PHE C 1 117 ? 78.077  -24.362 18.329  1.00 53.56  ? 324 PHE C CD1  1 
ATOM   3897  C  CD2  . PHE C 1 117 ? 79.240  -23.470 16.439  1.00 51.90  ? 324 PHE C CD2  1 
ATOM   3898  C  CE1  . PHE C 1 117 ? 79.111  -23.936 19.167  1.00 53.90  ? 324 PHE C CE1  1 
ATOM   3899  C  CE2  . PHE C 1 117 ? 80.271  -23.028 17.252  1.00 48.50  ? 324 PHE C CE2  1 
ATOM   3900  C  CZ   . PHE C 1 117 ? 80.217  -23.264 18.620  1.00 54.33  ? 324 PHE C CZ   1 
ATOM   3901  N  N    . ARG C 1 118 ? 75.710  -26.662 13.653  1.00 45.43  ? 325 ARG C N    1 
ATOM   3902  C  CA   . ARG C 1 118 ? 74.503  -26.719 12.835  1.00 48.65  ? 325 ARG C CA   1 
ATOM   3903  C  C    . ARG C 1 118 ? 73.931  -28.133 12.794  1.00 48.74  ? 325 ARG C C    1 
ATOM   3904  O  O    . ARG C 1 118 ? 74.670  -29.104 12.609  1.00 47.03  ? 325 ARG C O    1 
ATOM   3905  C  CB   . ARG C 1 118 ? 74.786  -26.221 11.417  1.00 54.47  ? 325 ARG C CB   1 
ATOM   3906  C  CG   . ARG C 1 118 ? 73.593  -26.333 10.449  1.00 55.53  ? 325 ARG C CG   1 
ATOM   3907  C  CD   . ARG C 1 118 ? 73.902  -25.649 9.109   1.00 53.88  ? 325 ARG C CD   1 
ATOM   3908  N  NE   . ARG C 1 118 ? 74.915  -26.408 8.369   1.00 61.54  ? 325 ARG C NE   1 
ATOM   3909  C  CZ   . ARG C 1 118 ? 75.394  -26.078 7.169   1.00 64.97  ? 325 ARG C CZ   1 
ATOM   3910  N  NH1  . ARG C 1 118 ? 74.945  -24.991 6.532   1.00 65.21  ? 325 ARG C NH1  1 
ATOM   3911  N  NH2  . ARG C 1 118 ? 76.332  -26.836 6.607   1.00 61.07  ? 325 ARG C NH2  1 
ATOM   3912  N  N    . GLY C 1 119 ? 72.615  -28.237 12.999  1.00 43.88  ? 326 GLY C N    1 
ATOM   3913  C  CA   . GLY C 1 119 ? 71.870  -29.453 12.767  1.00 45.27  ? 326 GLY C CA   1 
ATOM   3914  C  C    . GLY C 1 119 ? 70.775  -29.221 11.735  1.00 49.92  ? 326 GLY C C    1 
ATOM   3915  O  O    . GLY C 1 119 ? 70.640  -28.130 11.172  1.00 46.50  ? 326 GLY C O    1 
ATOM   3916  N  N    . LYS C 1 120 ? 70.000  -30.278 11.480  1.00 49.49  ? 327 LYS C N    1 
ATOM   3917  C  CA   . LYS C 1 120 ? 68.882  -30.171 10.552  1.00 50.68  ? 327 LYS C CA   1 
ATOM   3918  C  C    . LYS C 1 120 ? 67.648  -30.865 11.108  1.00 48.98  ? 327 LYS C C    1 
ATOM   3919  O  O    . LYS C 1 120 ? 67.728  -31.995 11.603  1.00 46.53  ? 327 LYS C O    1 
ATOM   3920  C  CB   . LYS C 1 120 ? 69.235  -30.746 9.178   1.00 50.49  ? 327 LYS C CB   1 
ATOM   3921  C  CG   . LYS C 1 120 ? 68.253  -30.280 8.076   1.00 57.35  ? 327 LYS C CG   1 
ATOM   3922  C  CD   . LYS C 1 120 ? 68.820  -29.171 7.186   1.00 53.85  ? 327 LYS C CD   1 
ATOM   3923  N  N    . MET C 1 121 ? 66.518  -30.177 10.968  1.00 52.73  ? 328 MET C N    1 
ATOM   3924  C  CA   . MET C 1 121 ? 65.220  -30.701 11.432  1.00 47.03  ? 328 MET C CA   1 
ATOM   3925  C  C    . MET C 1 121 ? 64.328  -31.019 10.235  1.00 48.77  ? 328 MET C C    1 
ATOM   3926  O  O    . MET C 1 121 ? 64.561  -30.456 9.165   1.00 49.44  ? 328 MET C O    1 
ATOM   3927  C  CB   . MET C 1 121 ? 64.491  -29.612 12.212  1.00 47.24  ? 328 MET C CB   1 
ATOM   3928  C  CG   . MET C 1 121 ? 65.017  -29.309 13.579  1.00 53.72  ? 328 MET C CG   1 
ATOM   3929  S  SD   . MET C 1 121 ? 64.378  -27.697 14.099  1.00 66.01  ? 328 MET C SD   1 
ATOM   3930  C  CE   . MET C 1 121 ? 63.857  -27.004 12.531  1.00 48.40  ? 328 MET C CE   1 
ATOM   3931  N  N    . VAL C 1 122 ? 63.323  -31.864 10.431  1.00 41.53  ? 329 VAL C N    1 
ATOM   3932  C  CA   . VAL C 1 122 ? 62.313  -32.134 9.373   1.00 49.73  ? 329 VAL C CA   1 
ATOM   3933  C  C    . VAL C 1 122 ? 60.967  -31.667 9.905   1.00 48.63  ? 329 VAL C C    1 
ATOM   3934  O  O    . VAL C 1 122 ? 60.654  -31.987 11.040  1.00 51.31  ? 329 VAL C O    1 
ATOM   3935  C  CB   . VAL C 1 122 ? 62.180  -33.624 9.015   1.00 52.36  ? 329 VAL C CB   1 
ATOM   3936  C  CG1  . VAL C 1 122 ? 62.760  -33.983 7.669   1.00 55.29  ? 329 VAL C CG1  1 
ATOM   3937  C  CG2  . VAL C 1 122 ? 62.613  -34.579 10.111  1.00 52.82  ? 329 VAL C CG2  1 
ATOM   3938  N  N    . SER C 1 123 ? 60.188  -30.973 9.090   1.00 45.82  ? 330 SER C N    1 
ATOM   3939  C  CA   . SER C 1 123 ? 58.817  -30.606 9.512   1.00 51.24  ? 330 SER C CA   1 
ATOM   3940  C  C    . SER C 1 123 ? 57.809  -31.286 8.583   1.00 53.58  ? 330 SER C C    1 
ATOM   3941  O  O    . SER C 1 123 ? 57.830  -30.994 7.390   1.00 51.26  ? 330 SER C O    1 
ATOM   3942  C  CB   . SER C 1 123 ? 58.625  -29.116 9.579   1.00 55.38  ? 330 SER C CB   1 
ATOM   3943  O  OG   . SER C 1 123 ? 59.789  -28.462 10.060  1.00 67.57  ? 330 SER C OG   1 
ATOM   3944  N  N    . TYR C 1 124 ? 56.989  -32.188 9.120   1.00 54.91  ? 331 TYR C N    1 
ATOM   3945  C  CA   . TYR C 1 124 ? 55.974  -32.869 8.335   1.00 56.53  ? 331 TYR C CA   1 
ATOM   3946  C  C    . TYR C 1 124 ? 54.658  -32.155 8.571   1.00 57.52  ? 331 TYR C C    1 
ATOM   3947  O  O    . TYR C 1 124 ? 54.327  -31.834 9.719   1.00 54.81  ? 331 TYR C O    1 
ATOM   3948  C  CB   . TYR C 1 124 ? 55.844  -34.333 8.746   1.00 52.35  ? 331 TYR C CB   1 
ATOM   3949  C  CG   . TYR C 1 124 ? 57.140  -35.109 8.657   1.00 65.04  ? 331 TYR C CG   1 
ATOM   3950  C  CD1  . TYR C 1 124 ? 57.696  -35.434 7.418   1.00 61.56  ? 331 TYR C CD1  1 
ATOM   3951  C  CD2  . TYR C 1 124 ? 57.818  -35.520 9.817   1.00 67.62  ? 331 TYR C CD2  1 
ATOM   3952  C  CE1  . TYR C 1 124 ? 58.886  -36.148 7.325   1.00 61.11  ? 331 TYR C CE1  1 
ATOM   3953  C  CE2  . TYR C 1 124 ? 59.015  -36.241 9.739   1.00 62.70  ? 331 TYR C CE2  1 
ATOM   3954  C  CZ   . TYR C 1 124 ? 59.547  -36.556 8.485   1.00 71.29  ? 331 TYR C CZ   1 
ATOM   3955  O  OH   . TYR C 1 124 ? 60.745  -37.267 8.384   1.00 66.62  ? 331 TYR C OH   1 
ATOM   3956  N  N    . ILE C 1 125 ? 53.930  -31.879 7.494   1.00 54.80  ? 332 ILE C N    1 
ATOM   3957  C  CA   . ILE C 1 125 ? 52.556  -31.398 7.572   1.00 52.20  ? 332 ILE C CA   1 
ATOM   3958  C  C    . ILE C 1 125 ? 51.684  -32.334 6.760   1.00 55.61  ? 332 ILE C C    1 
ATOM   3959  O  O    . ILE C 1 125 ? 51.987  -32.607 5.586   1.00 55.91  ? 332 ILE C O    1 
ATOM   3960  C  CB   . ILE C 1 125 ? 52.409  -29.954 7.065   1.00 51.16  ? 332 ILE C CB   1 
ATOM   3961  C  CG1  . ILE C 1 125 ? 53.187  -28.992 7.970   1.00 54.21  ? 332 ILE C CG1  1 
ATOM   3962  C  CG2  . ILE C 1 125 ? 50.932  -29.577 6.999   1.00 54.41  ? 332 ILE C CG2  1 
ATOM   3963  C  CD1  . ILE C 1 125 ? 53.975  -27.960 7.226   1.00 58.12  ? 332 ILE C CD1  1 
ATOM   3964  N  N    . GLN C 1 126 ? 50.621  -32.837 7.387   1.00 51.53  ? 333 GLN C N    1 
ATOM   3965  C  CA   . GLN C 1 126 ? 49.626  -33.659 6.716   1.00 57.15  ? 333 GLN C CA   1 
ATOM   3966  C  C    . GLN C 1 126 ? 48.225  -33.123 6.995   1.00 61.09  ? 333 GLN C C    1 
ATOM   3967  O  O    . GLN C 1 126 ? 47.864  -32.887 8.153   1.00 60.79  ? 333 GLN C O    1 
ATOM   3968  C  CB   . GLN C 1 126 ? 49.730  -35.120 7.153   1.00 60.46  ? 333 GLN C CB   1 
ATOM   3969  C  CG   . GLN C 1 126 ? 48.730  -36.030 6.451   1.00 65.31  ? 333 GLN C CG   1 
ATOM   3970  C  CD   . GLN C 1 126 ? 49.364  -37.285 5.903   1.00 72.94  ? 333 GLN C CD   1 
ATOM   3971  O  OE1  . GLN C 1 126 ? 50.110  -37.248 4.914   1.00 74.50  ? 333 GLN C OE1  1 
ATOM   3972  N  NE2  . GLN C 1 126 ? 49.076  -38.416 6.547   1.00 78.11  ? 333 GLN C NE2  1 
ATOM   3973  N  N    . CYS C 1 127 ? 47.447  -32.957 5.930   1.00 62.72  ? 334 CYS C N    1 
ATOM   3974  C  CA   . CYS C 1 127 ? 46.054  -32.476 6.071   1.00 61.42  ? 334 CYS C CA   1 
ATOM   3975  C  C    . CYS C 1 127 ? 45.197  -33.580 6.687   1.00 62.93  ? 334 CYS C C    1 
ATOM   3976  O  O    . CYS C 1 127 ? 45.494  -34.766 6.466   1.00 62.11  ? 334 CYS C O    1 
ATOM   3977  C  CB   . CYS C 1 127 ? 45.517  -32.025 4.723   1.00 50.61  ? 334 CYS C CB   1 
ATOM   3978  S  SG   . CYS C 1 127 ? 46.307  -30.522 4.102   1.00 60.47  ? 334 CYS C SG   1 
ATOM   3979  N  N    . LYS C 1 128 ? 44.148  -33.216 7.415   1.00 60.72  ? 335 LYS C N    1 
ATOM   3980  C  CA   . LYS C 1 128 ? 43.356  -34.247 8.131   1.00 62.41  ? 335 LYS C CA   1 
ATOM   3981  C  C    . LYS C 1 128 ? 42.136  -34.686 7.320   1.00 69.60  ? 335 LYS C C    1 
ATOM   3982  O  O    . LYS C 1 128 ? 41.612  -35.769 7.615   1.00 74.65  ? 335 LYS C O    1 
ATOM   3983  C  CB   . LYS C 1 128 ? 42.934  -33.706 9.496   1.00 61.62  ? 335 LYS C CB   1 
ATOM   3984  C  CG   . LYS C 1 128 ? 44.082  -33.374 10.436  1.00 64.54  ? 335 LYS C CG   1 
ATOM   3985  C  CD   . LYS C 1 128 ? 43.613  -32.786 11.741  1.00 65.80  ? 335 LYS C CD   1 
ATOM   3986  C  CE   . LYS C 1 128 ? 42.941  -33.808 12.630  1.00 73.80  ? 335 LYS C CE   1 
ATOM   3987  N  NZ   . LYS C 1 128 ? 43.933  -34.597 13.395  1.00 80.47  ? 335 LYS C NZ   1 
ATOM   3988  N  N    . GLU C 1 129 ? 41.718  -33.906 6.326   1.00 67.00  ? 336 GLU C N    1 
ATOM   3989  C  CA   . GLU C 1 129 ? 40.464  -34.236 5.605   1.00 66.90  ? 336 GLU C CA   1 
ATOM   3990  C  C    . GLU C 1 129 ? 40.729  -34.481 4.121   1.00 67.31  ? 336 GLU C C    1 
ATOM   3991  O  O    . GLU C 1 129 ? 39.949  -35.221 3.512   1.00 73.20  ? 336 GLU C O    1 
ATOM   3992  C  CB   . GLU C 1 129 ? 39.457  -33.110 5.819   1.00 69.70  ? 336 GLU C CB   1 
ATOM   3993  C  CG   . GLU C 1 129 ? 38.368  -33.463 6.811   1.00 70.13  ? 336 GLU C CG   1 
ATOM   3994  C  CD   . GLU C 1 129 ? 38.337  -32.578 8.042   1.00 76.69  ? 336 GLU C CD   1 
ATOM   3995  O  OE1  . GLU C 1 129 ? 38.268  -31.347 7.880   1.00 76.24  ? 336 GLU C OE1  1 
ATOM   3996  O  OE2  . GLU C 1 129 ? 38.379  -33.125 9.156   1.00 82.30  ? 336 GLU C OE2  1 
ATOM   3997  N  N    . VAL C 1 130 ? 41.760  -33.866 3.553   1.00 69.43  ? 337 VAL C N    1 
ATOM   3998  C  CA   . VAL C 1 130 ? 42.115  -34.135 2.173   1.00 62.87  ? 337 VAL C CA   1 
ATOM   3999  C  C    . VAL C 1 130 ? 43.467  -34.837 2.204   1.00 67.61  ? 337 VAL C C    1 
ATOM   4000  O  O    . VAL C 1 130 ? 44.137  -34.884 3.239   1.00 67.70  ? 337 VAL C O    1 
ATOM   4001  C  CB   . VAL C 1 130 ? 42.160  -32.857 1.316   1.00 67.69  ? 337 VAL C CB   1 
ATOM   4002  C  CG1  . VAL C 1 130 ? 40.770  -32.230 1.207   1.00 59.53  ? 337 VAL C CG1  1 
ATOM   4003  C  CG2  . VAL C 1 130 ? 43.145  -31.866 1.904   1.00 65.56  ? 337 VAL C CG2  1 
ATOM   4004  N  N    . ASP C 1 131 ? 43.850  -35.423 1.067   1.00 63.67  ? 338 ASP C N    1 
ATOM   4005  C  CA   . ASP C 1 131 ? 45.118  -36.139 0.969   1.00 60.91  ? 338 ASP C CA   1 
ATOM   4006  C  C    . ASP C 1 131 ? 46.166  -35.170 0.424   1.00 67.06  ? 338 ASP C C    1 
ATOM   4007  O  O    . ASP C 1 131 ? 46.437  -35.075 -0.778  1.00 59.83  ? 338 ASP C O    1 
ATOM   4008  C  CB   . ASP C 1 131 ? 44.985  -37.381 0.105   1.00 62.77  ? 338 ASP C CB   1 
ATOM   4009  C  CG   . ASP C 1 131 ? 46.327  -38.000 -0.199  1.00 73.52  ? 338 ASP C CG   1 
ATOM   4010  O  OD1  . ASP C 1 131 ? 47.163  -38.068 0.735   1.00 72.00  ? 338 ASP C OD1  1 
ATOM   4011  O  OD2  . ASP C 1 131 ? 46.559  -38.394 -1.365  1.00 81.52  ? 338 ASP C OD2  1 
ATOM   4012  N  N    . TYR C 1 132 ? 46.720  -34.382 1.343   1.00 66.61  ? 339 TYR C N    1 
ATOM   4013  C  CA   . TYR C 1 132 ? 47.776  -33.406 0.984   1.00 62.80  ? 339 TYR C CA   1 
ATOM   4014  C  C    . TYR C 1 132 ? 48.838  -33.501 2.072   1.00 55.57  ? 339 TYR C C    1 
ATOM   4015  O  O    . TYR C 1 132 ? 48.496  -33.473 3.257   1.00 58.68  ? 339 TYR C O    1 
ATOM   4016  C  CB   . TYR C 1 132 ? 47.185  -32.004 0.835   1.00 56.05  ? 339 TYR C CB   1 
ATOM   4017  C  CG   . TYR C 1 132 ? 48.017  -30.987 0.101   1.00 54.96  ? 339 TYR C CG   1 
ATOM   4018  C  CD1  . TYR C 1 132 ? 47.889  -30.818 -1.265  1.00 59.61  ? 339 TYR C CD1  1 
ATOM   4019  C  CD2  . TYR C 1 132 ? 48.897  -30.160 0.776   1.00 54.30  ? 339 TYR C CD2  1 
ATOM   4020  C  CE1  . TYR C 1 132 ? 48.633  -29.871 -1.948  1.00 55.21  ? 339 TYR C CE1  1 
ATOM   4021  C  CE2  . TYR C 1 132 ? 49.648  -29.208 0.109   1.00 58.08  ? 339 TYR C CE2  1 
ATOM   4022  C  CZ   . TYR C 1 132 ? 49.514  -29.062 -1.258  1.00 57.34  ? 339 TYR C CZ   1 
ATOM   4023  O  OH   . TYR C 1 132 ? 50.248  -28.127 -1.924  1.00 59.10  ? 339 TYR C OH   1 
ATOM   4024  N  N    . ARG C 1 133 ? 50.089  -33.637 1.669   1.00 53.87  ? 340 ARG C N    1 
ATOM   4025  C  CA   . ARG C 1 133 ? 51.185  -33.784 2.610   1.00 50.30  ? 340 ARG C CA   1 
ATOM   4026  C  C    . ARG C 1 133 ? 52.320  -32.882 2.162   1.00 45.01  ? 340 ARG C C    1 
ATOM   4027  O  O    . ARG C 1 133 ? 52.428  -32.562 0.988   1.00 50.65  ? 340 ARG C O    1 
ATOM   4028  C  CB   . ARG C 1 133 ? 51.640  -35.240 2.706   1.00 54.53  ? 340 ARG C CB   1 
ATOM   4029  C  CG   . ARG C 1 133 ? 52.399  -35.523 3.972   1.00 58.34  ? 340 ARG C CG   1 
ATOM   4030  C  CD   . ARG C 1 133 ? 53.111  -36.855 3.944   1.00 57.79  ? 340 ARG C CD   1 
ATOM   4031  N  NE   . ARG C 1 133 ? 54.013  -36.930 5.083   1.00 62.40  ? 340 ARG C NE   1 
ATOM   4032  C  CZ   . ARG C 1 133 ? 53.633  -37.297 6.304   1.00 64.07  ? 340 ARG C CZ   1 
ATOM   4033  N  NH1  . ARG C 1 133 ? 52.366  -37.652 6.530   1.00 61.31  ? 340 ARG C NH1  1 
ATOM   4034  N  NH2  . ARG C 1 133 ? 54.523  -37.323 7.296   1.00 54.96  ? 340 ARG C NH2  1 
ATOM   4035  N  N    . SER C 1 134 ? 53.157  -32.459 3.104   1.00 53.09  ? 341 SER C N    1 
ATOM   4036  C  CA   . SER C 1 134 ? 54.249  -31.567 2.753   1.00 43.97  ? 341 SER C CA   1 
ATOM   4037  C  C    . SER C 1 134 ? 55.377  -31.694 3.778   1.00 47.38  ? 341 SER C C    1 
ATOM   4038  O  O    . SER C 1 134 ? 55.132  -31.965 4.959   1.00 48.82  ? 341 SER C O    1 
ATOM   4039  C  CB   . SER C 1 134 ? 53.751  -30.126 2.663   1.00 43.23  ? 341 SER C CB   1 
ATOM   4040  O  OG   . SER C 1 134 ? 54.668  -29.328 1.948   1.00 54.77  ? 341 SER C OG   1 
ATOM   4041  N  N    . ASP C 1 135 ? 56.610  -31.573 3.273   1.00 44.99  ? 342 ASP C N    1 
ATOM   4042  C  CA   . ASP C 1 135 ? 57.834  -31.755 4.090   1.00 48.96  ? 342 ASP C CA   1 
ATOM   4043  C  C    . ASP C 1 135 ? 58.755  -30.546 3.917   1.00 45.74  ? 342 ASP C C    1 
ATOM   4044  O  O    . ASP C 1 135 ? 58.738  -29.959 2.828   1.00 46.65  ? 342 ASP C O    1 
ATOM   4045  C  CB   . ASP C 1 135 ? 58.610  -32.981 3.608   1.00 48.23  ? 342 ASP C CB   1 
ATOM   4046  C  CG   . ASP C 1 135 ? 58.097  -34.334 4.048   1.00 57.26  ? 342 ASP C CG   1 
ATOM   4047  O  OD1  . ASP C 1 135 ? 56.894  -34.455 4.325   1.00 69.86  ? 342 ASP C OD1  1 
ATOM   4048  O  OD2  . ASP C 1 135 ? 58.913  -35.266 4.082   1.00 62.14  ? 342 ASP C OD2  1 
ATOM   4049  N  N    . ARG C 1 136 ? 59.540  -30.202 4.941   1.00 45.22  ? 343 ARG C N    1 
ATOM   4050  C  CA   . ARG C 1 136 ? 60.523  -29.085 4.852   1.00 47.75  ? 343 ARG C CA   1 
ATOM   4051  C  C    . ARG C 1 136 ? 61.717  -29.358 5.768   1.00 48.14  ? 343 ARG C C    1 
ATOM   4052  O  O    . ARG C 1 136 ? 61.505  -29.665 6.946   1.00 44.77  ? 343 ARG C O    1 
ATOM   4053  C  CB   . ARG C 1 136 ? 59.887  -27.734 5.192   1.00 39.57  ? 343 ARG C CB   1 
ATOM   4054  C  CG   . ARG C 1 136 ? 60.848  -26.555 5.152   1.00 46.46  ? 343 ARG C CG   1 
ATOM   4055  C  CD   . ARG C 1 136 ? 61.425  -26.286 3.776   1.00 44.69  ? 343 ARG C CD   1 
ATOM   4056  N  NE   . ARG C 1 136 ? 60.402  -26.190 2.746   1.00 53.81  ? 343 ARG C NE   1 
ATOM   4057  C  CZ   . ARG C 1 136 ? 59.693  -25.101 2.480   1.00 50.94  ? 343 ARG C CZ   1 
ATOM   4058  N  NH1  . ARG C 1 136 ? 59.894  -23.993 3.169   1.00 52.05  ? 343 ARG C NH1  1 
ATOM   4059  N  NH2  . ARG C 1 136 ? 58.784  -25.126 1.526   1.00 45.06  ? 343 ARG C NH2  1 
ATOM   4060  N  N    . ARG C 1 137 ? 62.922  -29.229 5.228   1.00 46.44  ? 344 ARG C N    1 
ATOM   4061  C  CA   . ARG C 1 137 ? 64.156  -29.458 6.012   1.00 44.50  ? 344 ARG C CA   1 
ATOM   4062  C  C    . ARG C 1 137 ? 64.853  -28.120 6.255   1.00 49.83  ? 344 ARG C C    1 
ATOM   4063  O  O    . ARG C 1 137 ? 65.124  -27.423 5.272   1.00 46.89  ? 344 ARG C O    1 
ATOM   4064  C  CB   . ARG C 1 137 ? 65.037  -30.461 5.273   1.00 46.89  ? 344 ARG C CB   1 
ATOM   4065  C  CG   . ARG C 1 137 ? 64.627  -31.909 5.469   1.00 51.20  ? 344 ARG C CG   1 
ATOM   4066  C  CD   . ARG C 1 137 ? 64.731  -32.748 4.214   1.00 50.48  ? 344 ARG C CD   1 
ATOM   4067  N  NE   . ARG C 1 137 ? 63.911  -33.944 4.319   1.00 47.36  ? 344 ARG C NE   1 
ATOM   4068  C  CZ   . ARG C 1 137 ? 62.622  -34.000 4.015   1.00 50.04  ? 344 ARG C CZ   1 
ATOM   4069  N  NH1  . ARG C 1 137 ? 61.961  -35.134 4.148   1.00 45.90  ? 344 ARG C NH1  1 
ATOM   4070  N  NH2  . ARG C 1 137 ? 61.996  -32.923 3.579   1.00 46.04  ? 344 ARG C NH2  1 
ATOM   4071  N  N    . GLU C 1 138 ? 65.029  -27.772 7.524   1.00 49.46  ? 345 GLU C N    1 
ATOM   4072  C  CA   . GLU C 1 138 ? 65.599  -26.454 7.866   1.00 53.80  ? 345 GLU C CA   1 
ATOM   4073  C  C    . GLU C 1 138 ? 66.796  -26.621 8.792   1.00 50.56  ? 345 GLU C C    1 
ATOM   4074  O  O    . GLU C 1 138 ? 66.751  -27.460 9.695   1.00 53.98  ? 345 GLU C O    1 
ATOM   4075  C  CB   . GLU C 1 138 ? 64.542  -25.573 8.522   1.00 47.23  ? 345 GLU C CB   1 
ATOM   4076  C  CG   . GLU C 1 138 ? 63.385  -25.251 7.613   1.00 45.65  ? 345 GLU C CG   1 
ATOM   4077  C  CD   . GLU C 1 138 ? 62.262  -24.534 8.325   1.00 54.18  ? 345 GLU C CD   1 
ATOM   4078  O  OE1  . GLU C 1 138 ? 61.653  -25.136 9.222   1.00 50.47  ? 345 GLU C OE1  1 
ATOM   4079  O  OE2  . GLU C 1 138 ? 62.019  -23.378 7.984   1.00 50.53  ? 345 GLU C OE2  1 
ATOM   4080  N  N    . ASP C 1 139 ? 67.813  -25.812 8.560   1.00 47.32  ? 346 ASP C N    1 
ATOM   4081  C  CA   . ASP C 1 139 ? 69.011  -25.840 9.417   1.00 53.70  ? 346 ASP C CA   1 
ATOM   4082  C  C    . ASP C 1 139 ? 68.711  -25.153 10.745  1.00 49.19  ? 346 ASP C C    1 
ATOM   4083  O  O    . ASP C 1 139 ? 67.767  -24.360 10.802  1.00 50.82  ? 346 ASP C O    1 
ATOM   4084  C  CB   . ASP C 1 139 ? 70.174  -25.137 8.718   1.00 48.82  ? 346 ASP C CB   1 
ATOM   4085  C  CG   . ASP C 1 139 ? 70.811  -25.916 7.587   1.00 48.71  ? 346 ASP C CG   1 
ATOM   4086  O  OD1  . ASP C 1 139 ? 71.112  -27.095 7.795   1.00 44.91  ? 346 ASP C OD1  1 
ATOM   4087  O  OD2  . ASP C 1 139 ? 71.043  -25.316 6.527   1.00 51.29  ? 346 ASP C OD2  1 
ATOM   4088  N  N    . TYR C 1 140 ? 69.477  -25.480 11.776  1.00 47.78  ? 347 TYR C N    1 
ATOM   4089  C  CA   . TYR C 1 140 ? 69.360  -24.785 13.078  1.00 50.22  ? 347 TYR C CA   1 
ATOM   4090  C  C    . TYR C 1 140 ? 70.748  -24.714 13.694  1.00 51.84  ? 347 TYR C C    1 
ATOM   4091  O  O    . TYR C 1 140 ? 71.563  -25.601 13.441  1.00 52.38  ? 347 TYR C O    1 
ATOM   4092  C  CB   . TYR C 1 140 ? 68.396  -25.489 14.037  1.00 46.65  ? 347 TYR C CB   1 
ATOM   4093  C  CG   . TYR C 1 140 ? 68.806  -26.845 14.552  1.00 45.82  ? 347 TYR C CG   1 
ATOM   4094  C  CD1  . TYR C 1 140 ? 69.638  -26.982 15.650  1.00 43.82  ? 347 TYR C CD1  1 
ATOM   4095  C  CD2  . TYR C 1 140 ? 68.314  -27.995 13.968  1.00 45.76  ? 347 TYR C CD2  1 
ATOM   4096  C  CE1  . TYR C 1 140 ? 70.014  -28.225 16.121  1.00 45.81  ? 347 TYR C CE1  1 
ATOM   4097  C  CE2  . TYR C 1 140 ? 68.660  -29.246 14.440  1.00 46.11  ? 347 TYR C CE2  1 
ATOM   4098  C  CZ   . TYR C 1 140 ? 69.518  -29.360 15.514  1.00 47.98  ? 347 TYR C CZ   1 
ATOM   4099  O  OH   . TYR C 1 140 ? 69.864  -30.590 15.973  1.00 50.87  ? 347 TYR C OH   1 
ATOM   4100  N  N    . TYR C 1 141 ? 71.013  -23.671 14.464  1.00 47.00  ? 348 TYR C N    1 
ATOM   4101  C  CA   . TYR C 1 141 ? 72.283  -23.652 15.178  1.00 48.68  ? 348 TYR C CA   1 
ATOM   4102  C  C    . TYR C 1 141 ? 72.101  -23.772 16.679  1.00 51.44  ? 348 TYR C C    1 
ATOM   4103  O  O    . TYR C 1 141 ? 73.107  -23.827 17.409  1.00 48.72  ? 348 TYR C O    1 
ATOM   4104  C  CB   . TYR C 1 141 ? 73.076  -22.380 14.859  1.00 50.25  ? 348 TYR C CB   1 
ATOM   4105  C  CG   . TYR C 1 141 ? 73.726  -22.348 13.484  1.00 49.87  ? 348 TYR C CG   1 
ATOM   4106  C  CD1  . TYR C 1 141 ? 72.971  -22.525 12.328  1.00 48.28  ? 348 TYR C CD1  1 
ATOM   4107  C  CD2  . TYR C 1 141 ? 75.093  -22.118 13.345  1.00 54.99  ? 348 TYR C CD2  1 
ATOM   4108  C  CE1  . TYR C 1 141 ? 73.557  -22.470 11.083  1.00 54.29  ? 348 TYR C CE1  1 
ATOM   4109  C  CE2  . TYR C 1 141 ? 75.695  -22.058 12.094  1.00 55.34  ? 348 TYR C CE2  1 
ATOM   4110  C  CZ   . TYR C 1 141 ? 74.919  -22.234 10.973  1.00 53.68  ? 348 TYR C CZ   1 
ATOM   4111  O  OH   . TYR C 1 141 ? 75.501  -22.184 9.745   1.00 55.56  ? 348 TYR C OH   1 
ATOM   4112  N  N    . ASP C 1 142 ? 70.852  -23.815 17.147  1.00 42.16  ? 349 ASP C N    1 
ATOM   4113  C  CA   . ASP C 1 142 ? 70.501  -24.030 18.542  1.00 43.47  ? 349 ASP C CA   1 
ATOM   4114  C  C    . ASP C 1 142 ? 69.040  -24.455 18.574  1.00 43.14  ? 349 ASP C C    1 
ATOM   4115  O  O    . ASP C 1 142 ? 68.341  -24.386 17.562  1.00 41.43  ? 349 ASP C O    1 
ATOM   4116  C  CB   . ASP C 1 142 ? 70.765  -22.792 19.416  1.00 47.90  ? 349 ASP C CB   1 
ATOM   4117  C  CG   . ASP C 1 142 ? 69.825  -21.586 19.116  1.00 49.21  ? 349 ASP C CG   1 
ATOM   4118  O  OD1  . ASP C 1 142 ? 68.991  -21.623 18.177  1.00 50.44  ? 349 ASP C OD1  1 
ATOM   4119  O  OD2  . ASP C 1 142 ? 69.948  -20.564 19.837  1.00 46.35  ? 349 ASP C OD2  1 
ATOM   4120  N  N    . ILE C 1 143 ? 68.591  -24.916 19.742  1.00 43.16  ? 350 ILE C N    1 
ATOM   4121  C  CA   . ILE C 1 143 ? 67.217  -25.364 19.937  1.00 43.20  ? 350 ILE C CA   1 
ATOM   4122  C  C    . ILE C 1 143 ? 66.557  -24.552 21.049  1.00 43.59  ? 350 ILE C C    1 
ATOM   4123  O  O    . ILE C 1 143 ? 67.091  -24.469 22.158  1.00 43.99  ? 350 ILE C O    1 
ATOM   4124  C  CB   . ILE C 1 143 ? 67.152  -26.860 20.283  1.00 46.66  ? 350 ILE C CB   1 
ATOM   4125  C  CG1  . ILE C 1 143 ? 67.922  -27.712 19.262  1.00 46.79  ? 350 ILE C CG1  1 
ATOM   4126  C  CG2  . ILE C 1 143 ? 65.689  -27.299 20.404  1.00 44.56  ? 350 ILE C CG2  1 
ATOM   4127  C  CD1  . ILE C 1 143 ? 68.061  -29.199 19.710  1.00 40.62  ? 350 ILE C CD1  1 
ATOM   4128  N  N    . GLN C 1 144 ? 65.376  -23.996 20.755  1.00 43.56  ? 351 GLN C N    1 
ATOM   4129  C  CA   . GLN C 1 144 ? 64.474  -23.427 21.754  1.00 43.08  ? 351 GLN C CA   1 
ATOM   4130  C  C    . GLN C 1 144 ? 63.642  -24.526 22.416  1.00 47.89  ? 351 GLN C C    1 
ATOM   4131  O  O    . GLN C 1 144 ? 62.861  -25.217 21.742  1.00 46.72  ? 351 GLN C O    1 
ATOM   4132  C  CB   . GLN C 1 144 ? 63.540  -22.409 21.100  1.00 41.03  ? 351 GLN C CB   1 
ATOM   4133  C  CG   . GLN C 1 144 ? 64.226  -21.107 20.724  1.00 47.56  ? 351 GLN C CG   1 
ATOM   4134  C  CD   . GLN C 1 144 ? 65.212  -21.262 19.583  1.00 42.38  ? 351 GLN C CD   1 
ATOM   4135  O  OE1  . GLN C 1 144 ? 64.827  -21.466 18.441  1.00 43.06  ? 351 GLN C OE1  1 
ATOM   4136  N  NE2  . GLN C 1 144 ? 66.493  -21.173 19.897  1.00 43.74  ? 351 GLN C NE2  1 
ATOM   4137  N  N    . LEU C 1 145 ? 63.778  -24.678 23.734  1.00 45.98  ? 352 LEU C N    1 
ATOM   4138  C  CA   . LEU C 1 145 ? 63.066  -25.714 24.475  1.00 45.48  ? 352 LEU C CA   1 
ATOM   4139  C  C    . LEU C 1 145 ? 62.062  -25.068 25.402  1.00 53.99  ? 352 LEU C C    1 
ATOM   4140  O  O    . LEU C 1 145 ? 62.427  -24.202 26.203  1.00 60.09  ? 352 LEU C O    1 
ATOM   4141  C  CB   . LEU C 1 145 ? 64.013  -26.574 25.306  1.00 50.61  ? 352 LEU C CB   1 
ATOM   4142  C  CG   . LEU C 1 145 ? 65.055  -27.392 24.563  1.00 45.71  ? 352 LEU C CG   1 
ATOM   4143  C  CD1  . LEU C 1 145 ? 66.009  -27.947 25.601  1.00 43.76  ? 352 LEU C CD1  1 
ATOM   4144  C  CD2  . LEU C 1 145 ? 64.343  -28.506 23.785  1.00 45.55  ? 352 LEU C CD2  1 
ATOM   4145  N  N    . SER C 1 146 ? 60.840  -25.580 25.385  1.00 52.89  ? 353 SER C N    1 
ATOM   4146  C  CA   . SER C 1 146 ? 59.782  -25.034 26.264  1.00 51.00  ? 353 SER C CA   1 
ATOM   4147  C  C    . SER C 1 146 ? 59.971  -25.511 27.705  1.00 52.32  ? 353 SER C C    1 
ATOM   4148  O  O    . SER C 1 146 ? 60.396  -26.654 27.889  1.00 52.45  ? 353 SER C O    1 
ATOM   4149  C  CB   . SER C 1 146 ? 58.437  -25.359 25.709  1.00 51.71  ? 353 SER C CB   1 
ATOM   4150  O  OG   . SER C 1 146 ? 58.095  -24.453 24.676  1.00 63.23  ? 353 SER C OG   1 
ATOM   4151  N  N    . ILE C 1 147 ? 59.648  -24.660 28.683  1.00 56.08  ? 354 ILE C N    1 
ATOM   4152  C  CA   . ILE C 1 147 ? 59.895  -24.973 30.122  1.00 54.69  ? 354 ILE C CA   1 
ATOM   4153  C  C    . ILE C 1 147 ? 58.578  -25.095 30.883  1.00 56.10  ? 354 ILE C C    1 
ATOM   4154  O  O    . ILE C 1 147 ? 58.443  -26.059 31.634  1.00 57.03  ? 354 ILE C O    1 
ATOM   4155  C  CB   . ILE C 1 147 ? 60.763  -23.855 30.733  1.00 57.82  ? 354 ILE C CB   1 
ATOM   4156  C  CG1  . ILE C 1 147 ? 62.046  -23.616 29.934  1.00 58.43  ? 354 ILE C CG1  1 
ATOM   4157  C  CG2  . ILE C 1 147 ? 61.060  -24.107 32.203  1.00 53.32  ? 354 ILE C CG2  1 
ATOM   4158  C  CD1  . ILE C 1 147 ? 62.896  -24.840 29.781  1.00 53.96  ? 354 ILE C CD1  1 
ATOM   4159  N  N    . LYS C 1 148 ? 57.659  -24.143 30.714  1.00 47.66  ? 355 LYS C N    1 
ATOM   4160  C  CA   . LYS C 1 148 ? 56.414  -24.120 31.473  1.00 55.87  ? 355 LYS C CA   1 
ATOM   4161  C  C    . LYS C 1 148 ? 55.684  -25.462 31.406  1.00 56.81  ? 355 LYS C C    1 
ATOM   4162  O  O    . LYS C 1 148 ? 55.371  -25.967 30.323  1.00 59.02  ? 355 LYS C O    1 
ATOM   4163  C  CB   . LYS C 1 148 ? 55.511  -22.994 30.943  1.00 53.20  ? 355 LYS C CB   1 
ATOM   4164  N  N    . GLY C 1 149 ? 55.413  -26.042 32.570  1.00 55.49  ? 356 GLY C N    1 
ATOM   4165  C  CA   . GLY C 1 149 ? 54.687  -27.292 32.635  1.00 52.93  ? 356 GLY C CA   1 
ATOM   4166  C  C    . GLY C 1 149 ? 55.503  -28.515 32.293  1.00 60.56  ? 356 GLY C C    1 
ATOM   4167  O  O    . GLY C 1 149 ? 54.939  -29.620 32.242  1.00 57.79  ? 356 GLY C O    1 
ATOM   4168  N  N    . LYS C 1 150 ? 56.809  -28.360 32.062  1.00 54.78  ? 357 LYS C N    1 
ATOM   4169  C  CA   . LYS C 1 150 ? 57.694  -29.479 31.756  1.00 58.23  ? 357 LYS C CA   1 
ATOM   4170  C  C    . LYS C 1 150 ? 58.721  -29.595 32.876  1.00 55.39  ? 357 LYS C C    1 
ATOM   4171  O  O    . LYS C 1 150 ? 59.603  -28.742 33.016  1.00 60.38  ? 357 LYS C O    1 
ATOM   4172  C  CB   . LYS C 1 150 ? 58.359  -29.282 30.392  1.00 58.89  ? 357 LYS C CB   1 
ATOM   4173  C  CG   . LYS C 1 150 ? 57.474  -28.542 29.405  1.00 57.58  ? 357 LYS C CG   1 
ATOM   4174  C  CD   . LYS C 1 150 ? 56.720  -29.516 28.491  1.00 59.63  ? 357 LYS C CD   1 
ATOM   4175  C  CE   . LYS C 1 150 ? 55.568  -28.837 27.762  1.00 52.21  ? 357 LYS C CE   1 
ATOM   4176  N  NZ   . LYS C 1 150 ? 56.015  -27.608 27.035  1.00 65.15  ? 357 LYS C NZ   1 
ATOM   4177  N  N    . LYS C 1 151 ? 58.598  -30.635 33.687  1.00 61.22  ? 358 LYS C N    1 
ATOM   4178  C  CA   . LYS C 1 151 ? 59.477  -30.757 34.838  1.00 58.95  ? 358 LYS C CA   1 
ATOM   4179  C  C    . LYS C 1 151 ? 60.916  -31.051 34.439  1.00 62.68  ? 358 LYS C C    1 
ATOM   4180  O  O    . LYS C 1 151 ? 61.830  -30.774 35.228  1.00 61.87  ? 358 LYS C O    1 
ATOM   4181  C  CB   . LYS C 1 151 ? 58.960  -31.840 35.785  1.00 54.06  ? 358 LYS C CB   1 
ATOM   4182  C  CG   . LYS C 1 151 ? 57.507  -31.643 36.201  1.00 57.32  ? 358 LYS C CG   1 
ATOM   4183  N  N    . ASN C 1 152 ? 61.152  -31.573 33.235  1.00 55.17  ? 359 ASN C N    1 
ATOM   4184  C  CA   . ASN C 1 152 ? 62.513  -31.933 32.871  1.00 57.59  ? 359 ASN C CA   1 
ATOM   4185  C  C    . ASN C 1 152 ? 62.735  -31.790 31.365  1.00 58.45  ? 359 ASN C C    1 
ATOM   4186  O  O    . ASN C 1 152 ? 61.801  -31.637 30.578  1.00 60.20  ? 359 ASN C O    1 
ATOM   4187  C  CB   . ASN C 1 152 ? 62.838  -33.356 33.359  1.00 59.09  ? 359 ASN C CB   1 
ATOM   4188  C  CG   . ASN C 1 152 ? 61.983  -34.407 32.694  1.00 54.44  ? 359 ASN C CG   1 
ATOM   4189  O  OD1  . ASN C 1 152 ? 61.982  -34.541 31.465  1.00 59.01  ? 359 ASN C OD1  1 
ATOM   4190  N  ND2  . ASN C 1 152 ? 61.258  -35.169 33.494  1.00 53.32  ? 359 ASN C ND2  1 
ATOM   4191  N  N    . ILE C 1 153 ? 64.002  -31.887 30.966  1.00 58.83  ? 360 ILE C N    1 
ATOM   4192  C  CA   . ILE C 1 153 ? 64.349  -31.661 29.571  1.00 53.52  ? 360 ILE C CA   1 
ATOM   4193  C  C    . ILE C 1 153 ? 63.770  -32.747 28.676  1.00 53.65  ? 360 ILE C C    1 
ATOM   4194  O  O    . ILE C 1 153 ? 63.429  -32.487 27.515  1.00 54.09  ? 360 ILE C O    1 
ATOM   4195  C  CB   . ILE C 1 153 ? 65.874  -31.544 29.442  1.00 51.19  ? 360 ILE C CB   1 
ATOM   4196  C  CG1  . ILE C 1 153 ? 66.234  -30.683 28.242  1.00 45.54  ? 360 ILE C CG1  1 
ATOM   4197  C  CG2  . ILE C 1 153 ? 66.526  -32.938 29.373  1.00 54.21  ? 360 ILE C CG2  1 
ATOM   4198  C  CD1  . ILE C 1 153 ? 67.717  -30.673 27.953  1.00 51.80  ? 360 ILE C CD1  1 
ATOM   4199  N  N    . PHE C 1 154 ? 63.580  -33.944 29.208  1.00 57.54  ? 361 PHE C N    1 
ATOM   4200  C  CA   . PHE C 1 154 ? 63.010  -35.048 28.405  1.00 50.26  ? 361 PHE C CA   1 
ATOM   4201  C  C    . PHE C 1 154 ? 61.541  -34.736 28.138  1.00 53.53  ? 361 PHE C C    1 
ATOM   4202  O  O    . PHE C 1 154 ? 61.116  -34.961 27.007  1.00 58.94  ? 361 PHE C O    1 
ATOM   4203  C  CB   . PHE C 1 154 ? 63.275  -36.388 29.081  1.00 49.36  ? 361 PHE C CB   1 
ATOM   4204  C  CG   . PHE C 1 154 ? 64.721  -36.795 29.109  1.00 55.52  ? 361 PHE C CG   1 
ATOM   4205  C  CD1  . PHE C 1 154 ? 65.317  -37.356 27.994  1.00 54.07  ? 361 PHE C CD1  1 
ATOM   4206  C  CD2  . PHE C 1 154 ? 65.484  -36.616 30.249  1.00 51.77  ? 361 PHE C CD2  1 
ATOM   4207  C  CE1  . PHE C 1 154 ? 66.648  -37.734 28.021  1.00 55.54  ? 361 PHE C CE1  1 
ATOM   4208  C  CE2  . PHE C 1 154 ? 66.814  -36.997 30.275  1.00 56.44  ? 361 PHE C CE2  1 
ATOM   4209  C  CZ   . PHE C 1 154 ? 67.392  -37.554 29.162  1.00 56.30  ? 361 PHE C CZ   1 
ATOM   4210  N  N    . GLU C 1 155 ? 60.797  -34.237 29.129  1.00 55.06  ? 362 GLU C N    1 
ATOM   4211  C  CA   . GLU C 1 155 ? 59.439  -33.803 28.815  1.00 58.45  ? 362 GLU C CA   1 
ATOM   4212  C  C    . GLU C 1 155 ? 59.469  -32.756 27.725  1.00 54.76  ? 362 GLU C C    1 
ATOM   4213  O  O    . GLU C 1 155 ? 58.587  -32.719 26.859  1.00 58.47  ? 362 GLU C O    1 
ATOM   4214  C  CB   . GLU C 1 155 ? 58.738  -33.245 30.044  1.00 53.23  ? 362 GLU C CB   1 
ATOM   4215  C  CG   . GLU C 1 155 ? 58.262  -34.318 30.978  1.00 59.76  ? 362 GLU C CG   1 
ATOM   4216  C  CD   . GLU C 1 155 ? 57.365  -33.775 32.046  1.00 58.23  ? 362 GLU C CD   1 
ATOM   4217  O  OE1  . GLU C 1 155 ? 56.366  -33.102 31.712  1.00 71.18  ? 362 GLU C OE1  1 
ATOM   4218  O  OE2  . GLU C 1 155 ? 57.674  -34.001 33.218  1.00 60.01  ? 362 GLU C OE2  1 
ATOM   4219  N  N    . SER C 1 156 ? 60.501  -31.919 27.734  1.00 52.36  ? 363 SER C N    1 
ATOM   4220  C  CA   . SER C 1 156 ? 60.516  -30.785 26.830  1.00 55.64  ? 363 SER C CA   1 
ATOM   4221  C  C    . SER C 1 156 ? 60.792  -31.252 25.409  1.00 56.26  ? 363 SER C C    1 
ATOM   4222  O  O    . SER C 1 156 ? 60.084  -30.853 24.478  1.00 47.41  ? 363 SER C O    1 
ATOM   4223  C  CB   . SER C 1 156 ? 61.539  -29.756 27.324  1.00 52.70  ? 363 SER C CB   1 
ATOM   4224  O  OG   . SER C 1 156 ? 61.808  -28.778 26.346  1.00 56.49  ? 363 SER C OG   1 
ATOM   4225  N  N    . PHE C 1 157 ? 61.760  -32.169 25.247  1.00 54.45  ? 364 PHE C N    1 
ATOM   4226  C  CA   . PHE C 1 157 ? 62.049  -32.719 23.928  1.00 48.56  ? 364 PHE C CA   1 
ATOM   4227  C  C    . PHE C 1 157 ? 60.858  -33.491 23.367  1.00 49.45  ? 364 PHE C C    1 
ATOM   4228  O  O    . PHE C 1 157 ? 60.542  -33.377 22.177  1.00 53.35  ? 364 PHE C O    1 
ATOM   4229  C  CB   . PHE C 1 157 ? 63.272  -33.622 23.995  1.00 45.86  ? 364 PHE C CB   1 
ATOM   4230  C  CG   . PHE C 1 157 ? 64.569  -32.902 23.778  1.00 48.44  ? 364 PHE C CG   1 
ATOM   4231  C  CD1  . PHE C 1 157 ? 64.982  -32.554 22.495  1.00 46.98  ? 364 PHE C CD1  1 
ATOM   4232  C  CD2  . PHE C 1 157 ? 65.406  -32.620 24.846  1.00 48.60  ? 364 PHE C CD2  1 
ATOM   4233  C  CE1  . PHE C 1 157 ? 66.196  -31.913 22.287  1.00 45.53  ? 364 PHE C CE1  1 
ATOM   4234  C  CE2  . PHE C 1 157 ? 66.627  -31.977 24.654  1.00 49.73  ? 364 PHE C CE2  1 
ATOM   4235  C  CZ   . PHE C 1 157 ? 67.021  -31.617 23.374  1.00 51.48  ? 364 PHE C CZ   1 
ATOM   4236  N  N    . VAL C 1 158 ? 60.215  -34.316 24.192  1.00 52.24  ? 365 VAL C N    1 
ATOM   4237  C  CA   . VAL C 1 158 ? 59.024  -35.040 23.747  1.00 54.14  ? 365 VAL C CA   1 
ATOM   4238  C  C    . VAL C 1 158 ? 57.982  -34.057 23.225  1.00 56.44  ? 365 VAL C C    1 
ATOM   4239  O  O    . VAL C 1 158 ? 57.360  -34.276 22.175  1.00 55.39  ? 365 VAL C O    1 
ATOM   4240  C  CB   . VAL C 1 158 ? 58.454  -35.893 24.898  1.00 50.09  ? 365 VAL C CB   1 
ATOM   4241  C  CG1  . VAL C 1 158 ? 56.988  -36.284 24.620  1.00 43.59  ? 365 VAL C CG1  1 
ATOM   4242  C  CG2  . VAL C 1 158 ? 59.326  -37.111 25.147  1.00 49.95  ? 365 VAL C CG2  1 
ATOM   4243  N  N    . ASP C 1 159 ? 57.774  -32.964 23.958  1.00 49.24  ? 366 ASP C N    1 
ATOM   4244  C  CA   . ASP C 1 159 ? 56.898  -31.906 23.476  1.00 50.22  ? 366 ASP C CA   1 
ATOM   4245  C  C    . ASP C 1 159 ? 57.392  -31.356 22.150  1.00 53.40  ? 366 ASP C C    1 
ATOM   4246  O  O    . ASP C 1 159 ? 56.602  -31.145 21.224  1.00 52.78  ? 366 ASP C O    1 
ATOM   4247  C  CB   . ASP C 1 159 ? 56.820  -30.791 24.516  1.00 54.29  ? 366 ASP C CB   1 
ATOM   4248  C  CG   . ASP C 1 159 ? 55.643  -29.870 24.287  1.00 62.00  ? 366 ASP C CG   1 
ATOM   4249  O  OD1  . ASP C 1 159 ? 54.504  -30.387 24.216  1.00 66.32  ? 366 ASP C OD1  1 
ATOM   4250  O  OD2  . ASP C 1 159 ? 55.854  -28.637 24.171  1.00 60.48  ? 366 ASP C OD2  1 
ATOM   4251  N  N    . TYR C 1 160 ? 58.706  -31.135 22.036  1.00 50.21  ? 367 TYR C N    1 
ATOM   4252  C  CA   . TYR C 1 160 ? 59.253  -30.561 20.817  1.00 47.38  ? 367 TYR C CA   1 
ATOM   4253  C  C    . TYR C 1 160 ? 58.877  -31.378 19.591  1.00 50.83  ? 367 TYR C C    1 
ATOM   4254  O  O    . TYR C 1 160 ? 58.636  -30.818 18.516  1.00 51.15  ? 367 TYR C O    1 
ATOM   4255  C  CB   . TYR C 1 160 ? 60.765  -30.429 20.925  1.00 47.78  ? 367 TYR C CB   1 
ATOM   4256  C  CG   . TYR C 1 160 ? 61.329  -29.443 19.928  1.00 46.16  ? 367 TYR C CG   1 
ATOM   4257  C  CD1  . TYR C 1 160 ? 61.674  -29.852 18.638  1.00 46.21  ? 367 TYR C CD1  1 
ATOM   4258  C  CD2  . TYR C 1 160 ? 61.516  -28.111 20.264  1.00 35.49  ? 367 TYR C CD2  1 
ATOM   4259  C  CE1  . TYR C 1 160 ? 62.203  -28.940 17.703  1.00 47.73  ? 367 TYR C CE1  1 
ATOM   4260  C  CE2  . TYR C 1 160 ? 62.038  -27.199 19.343  1.00 41.10  ? 367 TYR C CE2  1 
ATOM   4261  C  CZ   . TYR C 1 160 ? 62.386  -27.622 18.069  1.00 46.16  ? 367 TYR C CZ   1 
ATOM   4262  O  OH   . TYR C 1 160 ? 62.894  -26.729 17.148  1.00 47.34  ? 367 TYR C OH   1 
ATOM   4263  N  N    . VAL C 1 161 ? 58.789  -32.701 19.734  1.00 51.44  ? 368 VAL C N    1 
ATOM   4264  C  CA   . VAL C 1 161 ? 58.548  -33.573 18.593  1.00 48.70  ? 368 VAL C CA   1 
ATOM   4265  C  C    . VAL C 1 161 ? 57.125  -34.089 18.536  1.00 53.95  ? 368 VAL C C    1 
ATOM   4266  O  O    . VAL C 1 161 ? 56.796  -34.849 17.617  1.00 52.10  ? 368 VAL C O    1 
ATOM   4267  C  CB   . VAL C 1 161 ? 59.537  -34.755 18.592  1.00 50.41  ? 368 VAL C CB   1 
ATOM   4268  C  CG1  . VAL C 1 161 ? 60.921  -34.253 18.291  1.00 52.26  ? 368 VAL C CG1  1 
ATOM   4269  C  CG2  . VAL C 1 161 ? 59.531  -35.462 19.915  1.00 45.69  ? 368 VAL C CG2  1 
ATOM   4270  N  N    . ALA C 1 162 ? 56.268  -33.697 19.475  1.00 51.41  ? 369 ALA C N    1 
ATOM   4271  C  CA   . ALA C 1 162 ? 54.892  -34.162 19.455  1.00 53.45  ? 369 ALA C CA   1 
ATOM   4272  C  C    . ALA C 1 162 ? 54.112  -33.529 18.304  1.00 54.29  ? 369 ALA C C    1 
ATOM   4273  O  O    . ALA C 1 162 ? 54.435  -32.447 17.813  1.00 52.66  ? 369 ALA C O    1 
ATOM   4274  C  CB   . ALA C 1 162 ? 54.198  -33.851 20.779  1.00 48.52  ? 369 ALA C CB   1 
ATOM   4275  N  N    . VAL C 1 163 ? 53.049  -34.219 17.901  1.00 54.34  ? 370 VAL C N    1 
ATOM   4276  C  CA   . VAL C 1 163 ? 52.226  -33.764 16.790  1.00 57.37  ? 370 VAL C CA   1 
ATOM   4277  C  C    . VAL C 1 163 ? 51.322  -32.612 17.223  1.00 56.75  ? 370 VAL C C    1 
ATOM   4278  O  O    . VAL C 1 163 ? 50.817  -32.565 18.351  1.00 61.55  ? 370 VAL C O    1 
ATOM   4279  C  CB   . VAL C 1 163 ? 51.403  -34.944 16.241  1.00 59.79  ? 370 VAL C CB   1 
ATOM   4280  C  CG1  . VAL C 1 163 ? 50.852  -34.610 14.845  1.00 56.68  ? 370 VAL C CG1  1 
ATOM   4281  C  CG2  . VAL C 1 163 ? 52.261  -36.189 16.204  1.00 51.20  ? 370 VAL C CG2  1 
ATOM   4282  N  N    . GLU C 1 164 ? 51.130  -31.676 16.306  1.00 56.23  ? 371 GLU C N    1 
ATOM   4283  C  CA   . GLU C 1 164 ? 50.332  -30.476 16.610  1.00 56.01  ? 371 GLU C CA   1 
ATOM   4284  C  C    . GLU C 1 164 ? 49.198  -30.324 15.609  1.00 57.46  ? 371 GLU C C    1 
ATOM   4285  O  O    . GLU C 1 164 ? 49.381  -30.685 14.461  1.00 53.52  ? 371 GLU C O    1 
ATOM   4286  C  CB   . GLU C 1 164 ? 51.236  -29.255 16.501  1.00 52.21  ? 371 GLU C CB   1 
ATOM   4287  C  CG   . GLU C 1 164 ? 51.116  -28.291 17.654  1.00 56.73  ? 371 GLU C CG   1 
ATOM   4288  C  CD   . GLU C 1 164 ? 51.652  -26.925 17.281  1.00 64.90  ? 371 GLU C CD   1 
ATOM   4289  O  OE1  . GLU C 1 164 ? 50.863  -25.966 17.282  1.00 66.01  ? 371 GLU C OE1  1 
ATOM   4290  O  OE2  . GLU C 1 164 ? 52.852  -26.835 16.968  1.00 58.31  ? 371 GLU C OE2  1 
ATOM   4291  N  N    . GLN C 1 165 ? 48.070  -29.799 16.054  1.00 60.01  ? 372 GLN C N    1 
ATOM   4292  C  CA   . GLN C 1 165 ? 46.929  -29.500 15.193  1.00 61.75  ? 372 GLN C CA   1 
ATOM   4293  C  C    . GLN C 1 165 ? 47.049  -28.084 14.649  1.00 59.06  ? 372 GLN C C    1 
ATOM   4294  O  O    . GLN C 1 165 ? 47.410  -27.163 15.384  1.00 59.67  ? 372 GLN C O    1 
ATOM   4295  C  CB   . GLN C 1 165 ? 45.611  -29.660 15.947  1.00 59.45  ? 372 GLN C CB   1 
ATOM   4296  C  CG   . GLN C 1 165 ? 45.563  -30.914 16.752  1.00 57.56  ? 372 GLN C CG   1 
ATOM   4297  C  CD   . GLN C 1 165 ? 45.813  -32.100 15.892  1.00 61.32  ? 372 GLN C CD   1 
ATOM   4298  O  OE1  . GLN C 1 165 ? 45.257  -32.207 14.811  1.00 66.71  ? 372 GLN C OE1  1 
ATOM   4299  N  NE2  . GLN C 1 165 ? 46.676  -32.997 16.345  1.00 73.42  ? 372 GLN C NE2  1 
ATOM   4300  N  N    . LEU C 1 166 ? 46.774  -27.928 13.356  1.00 58.83  ? 373 LEU C N    1 
ATOM   4301  C  CA   . LEU C 1 166 ? 46.661  -26.631 12.696  1.00 59.43  ? 373 LEU C CA   1 
ATOM   4302  C  C    . LEU C 1 166 ? 45.169  -26.402 12.405  1.00 65.49  ? 373 LEU C C    1 
ATOM   4303  O  O    . LEU C 1 166 ? 44.678  -26.723 11.321  1.00 67.47  ? 373 LEU C O    1 
ATOM   4304  C  CB   . LEU C 1 166 ? 47.515  -26.588 11.431  1.00 58.60  ? 373 LEU C CB   1 
ATOM   4305  C  CG   . LEU C 1 166 ? 49.027  -26.613 11.712  1.00 61.25  ? 373 LEU C CG   1 
ATOM   4306  C  CD1  . LEU C 1 166 ? 49.862  -26.421 10.458  1.00 54.42  ? 373 LEU C CD1  1 
ATOM   4307  C  CD2  . LEU C 1 166 ? 49.392  -25.577 12.748  1.00 55.59  ? 373 LEU C CD2  1 
ATOM   4308  N  N    . ASP C 1 167 ? 44.484  -25.762 13.352  1.00 64.17  ? 374 ASP C N    1 
ATOM   4309  C  CA   . ASP C 1 167 ? 43.023  -25.567 13.223  1.00 55.15  ? 374 ASP C CA   1 
ATOM   4310  C  C    . ASP C 1 167 ? 42.644  -24.094 13.282  1.00 60.63  ? 374 ASP C C    1 
ATOM   4311  O  O    . ASP C 1 167 ? 43.487  -23.290 13.695  1.00 61.10  ? 374 ASP C O    1 
ATOM   4312  C  CB   . ASP C 1 167 ? 42.295  -26.263 14.371  1.00 59.25  ? 374 ASP C CB   1 
ATOM   4313  C  CG   . ASP C 1 167 ? 42.413  -27.776 14.401  1.00 68.14  ? 374 ASP C CG   1 
ATOM   4314  O  OD1  . ASP C 1 167 ? 42.582  -28.381 13.328  1.00 72.74  ? 374 ASP C OD1  1 
ATOM   4315  O  OD2  . ASP C 1 167 ? 42.321  -28.337 15.506  1.00 72.71  ? 374 ASP C OD2  1 
ATOM   4316  N  N    . GLY C 1 168 ? 41.413  -23.765 12.889  1.00 62.45  ? 375 GLY C N    1 
ATOM   4317  C  CA   . GLY C 1 168 ? 40.880  -22.396 13.028  1.00 56.70  ? 375 GLY C CA   1 
ATOM   4318  C  C    . GLY C 1 168 ? 41.702  -21.312 12.381  1.00 55.88  ? 375 GLY C C    1 
ATOM   4319  O  O    . GLY C 1 168 ? 41.756  -21.282 11.146  1.00 56.60  ? 375 GLY C O    1 
ATOM   4320  N  N    . ASP C 1 169 ? 42.257  -20.412 13.193  1.00 53.74  ? 376 ASP C N    1 
ATOM   4321  C  CA   . ASP C 1 169 ? 43.021  -19.263 12.641  1.00 53.90  ? 376 ASP C CA   1 
ATOM   4322  C  C    . ASP C 1 169 ? 44.389  -19.756 12.201  1.00 52.56  ? 376 ASP C C    1 
ATOM   4323  O  O    . ASP C 1 169 ? 45.202  -18.932 11.788  1.00 49.10  ? 376 ASP C O    1 
ATOM   4324  C  CB   . ASP C 1 169 ? 43.127  -18.127 13.652  1.00 40.96  ? 376 ASP C CB   1 
ATOM   4325  C  CG   . ASP C 1 169 ? 43.297  -16.759 13.030  1.00 50.99  ? 376 ASP C CG   1 
ATOM   4326  O  OD1  . ASP C 1 169 ? 42.920  -16.590 11.859  1.00 53.90  ? 376 ASP C OD1  1 
ATOM   4327  O  OD2  . ASP C 1 169 ? 43.801  -15.878 13.732  1.00 50.60  ? 376 ASP C OD2  1 
ATOM   4328  N  N    . ASN C 1 170 ? 44.603  -21.064 12.261  1.00 52.41  ? 377 ASN C N    1 
ATOM   4329  C  CA   . ASN C 1 170 ? 45.925  -21.584 11.948  1.00 57.38  ? 377 ASN C CA   1 
ATOM   4330  C  C    . ASN C 1 170 ? 45.834  -22.774 11.019  1.00 59.40  ? 377 ASN C C    1 
ATOM   4331  O  O    . ASN C 1 170 ? 46.690  -23.661 11.060  1.00 58.34  ? 377 ASN C O    1 
ATOM   4332  C  CB   . ASN C 1 170 ? 46.660  -21.986 13.208  1.00 50.86  ? 377 ASN C CB   1 
ATOM   4333  C  CG   . ASN C 1 170 ? 47.170  -20.806 13.966  1.00 50.46  ? 377 ASN C CG   1 
ATOM   4334  O  OD1  . ASN C 1 170 ? 47.872  -19.962 13.414  1.00 51.59  ? 377 ASN C OD1  1 
ATOM   4335  N  ND2  . ASN C 1 170 ? 46.818  -20.728 15.240  1.00 47.99  ? 377 ASN C ND2  1 
ATOM   4336  N  N    . LYS C 1 171 ? 44.790  -22.821 10.201  1.00 59.04  ? 378 LYS C N    1 
ATOM   4337  C  CA   . LYS C 1 171 ? 44.715  -23.844 9.179   1.00 57.28  ? 378 LYS C CA   1 
ATOM   4338  C  C    . LYS C 1 171 ? 45.884  -23.678 8.217   1.00 57.34  ? 378 LYS C C    1 
ATOM   4339  O  O    . LYS C 1 171 ? 46.448  -22.587 8.061   1.00 57.05  ? 378 LYS C O    1 
ATOM   4340  C  CB   . LYS C 1 171 ? 43.373  -23.768 8.439   1.00 56.80  ? 378 LYS C CB   1 
ATOM   4341  C  CG   . LYS C 1 171 ? 42.244  -24.543 9.100   1.00 59.19  ? 378 LYS C CG   1 
ATOM   4342  N  N    . TYR C 1 172 ? 46.258  -24.786 7.588   1.00 58.11  ? 379 TYR C N    1 
ATOM   4343  C  CA   . TYR C 1 172 ? 47.390  -24.841 6.678   1.00 55.07  ? 379 TYR C CA   1 
ATOM   4344  C  C    . TYR C 1 172 ? 46.926  -24.557 5.255   1.00 58.79  ? 379 TYR C C    1 
ATOM   4345  O  O    . TYR C 1 172 ? 45.862  -25.010 4.824   1.00 59.90  ? 379 TYR C O    1 
ATOM   4346  C  CB   . TYR C 1 172 ? 48.058  -26.215 6.784   1.00 56.35  ? 379 TYR C CB   1 
ATOM   4347  C  CG   . TYR C 1 172 ? 48.964  -26.613 5.644   1.00 57.39  ? 379 TYR C CG   1 
ATOM   4348  C  CD1  . TYR C 1 172 ? 50.074  -25.858 5.325   1.00 50.75  ? 379 TYR C CD1  1 
ATOM   4349  C  CD2  . TYR C 1 172 ? 48.724  -27.776 4.914   1.00 61.06  ? 379 TYR C CD2  1 
ATOM   4350  C  CE1  . TYR C 1 172 ? 50.911  -26.221 4.298   1.00 56.61  ? 379 TYR C CE1  1 
ATOM   4351  C  CE2  . TYR C 1 172 ? 49.557  -28.151 3.877   1.00 58.68  ? 379 TYR C CE2  1 
ATOM   4352  C  CZ   . TYR C 1 172 ? 50.655  -27.363 3.579   1.00 59.58  ? 379 TYR C CZ   1 
ATOM   4353  O  OH   . TYR C 1 172 ? 51.515  -27.701 2.562   1.00 56.19  ? 379 TYR C OH   1 
ATOM   4354  N  N    . ASP C 1 173 ? 47.705  -23.779 4.512   1.00 52.34  ? 380 ASP C N    1 
ATOM   4355  C  CA   . ASP C 1 173 ? 47.371  -23.491 3.095   1.00 60.47  ? 380 ASP C CA   1 
ATOM   4356  C  C    . ASP C 1 173 ? 47.738  -24.701 2.237   1.00 62.03  ? 380 ASP C C    1 
ATOM   4357  O  O    . ASP C 1 173 ? 48.925  -24.873 1.951   1.00 60.61  ? 380 ASP C O    1 
ATOM   4358  C  CB   . ASP C 1 173 ? 48.047  -22.206 2.609   1.00 60.94  ? 380 ASP C CB   1 
ATOM   4359  C  CG   . ASP C 1 173 ? 47.687  -21.797 1.192   1.00 65.58  ? 380 ASP C CG   1 
ATOM   4360  O  OD1  . ASP C 1 173 ? 46.546  -22.059 0.770   1.00 73.35  ? 380 ASP C OD1  1 
ATOM   4361  O  OD2  . ASP C 1 173 ? 48.553  -21.208 0.526   1.00 65.95  ? 380 ASP C OD2  1 
ATOM   4362  N  N    . ALA C 1 174 ? 46.742  -25.479 1.819   1.00 57.63  ? 381 ALA C N    1 
ATOM   4363  C  CA   . ALA C 1 174 ? 46.986  -26.682 0.994   1.00 59.75  ? 381 ALA C CA   1 
ATOM   4364  C  C    . ALA C 1 174 ? 46.828  -26.373 -0.497  1.00 61.87  ? 381 ALA C C    1 
ATOM   4365  O  O    . ALA C 1 174 ? 46.287  -27.219 -1.215  1.00 65.78  ? 381 ALA C O    1 
ATOM   4366  C  CB   . ALA C 1 174 ? 46.051  -27.769 1.427   1.00 59.72  ? 381 ALA C CB   1 
ATOM   4367  N  N    . GLY C 1 175 ? 47.296  -25.211 -0.939  1.00 59.65  ? 382 GLY C N    1 
ATOM   4368  C  CA   . GLY C 1 175 ? 47.238  -24.831 -2.357  1.00 62.14  ? 382 GLY C CA   1 
ATOM   4369  C  C    . GLY C 1 175 ? 45.860  -24.963 -2.959  1.00 70.31  ? 382 GLY C C    1 
ATOM   4370  O  O    . GLY C 1 175 ? 44.995  -24.151 -2.617  1.00 64.12  ? 382 GLY C O    1 
ATOM   4371  N  N    . GLU C 1 176 ? 45.678  -25.946 -3.839  1.00 70.43  ? 383 GLU C N    1 
ATOM   4372  C  CA   . GLU C 1 176 ? 44.393  -26.125 -4.551  1.00 65.56  ? 383 GLU C CA   1 
ATOM   4373  C  C    . GLU C 1 176 ? 43.297  -26.485 -3.556  1.00 66.33  ? 383 GLU C C    1 
ATOM   4374  O  O    . GLU C 1 176 ? 42.125  -26.274 -3.889  1.00 69.39  ? 383 GLU C O    1 
ATOM   4375  C  CB   . GLU C 1 176 ? 44.538  -27.215 -5.609  1.00 60.31  ? 383 GLU C CB   1 
ATOM   4376  C  CG   . GLU C 1 176 ? 45.757  -27.042 -6.496  1.00 69.49  ? 383 GLU C CG   1 
ATOM   4377  N  N    . HIS C 1 177 ? 43.659  -26.984 -2.379  1.00 64.99  ? 384 HIS C N    1 
ATOM   4378  C  CA   . HIS C 1 177 ? 42.594  -27.273 -1.431  1.00 63.68  ? 384 HIS C CA   1 
ATOM   4379  C  C    . HIS C 1 177 ? 42.264  -26.093 -0.532  1.00 60.56  ? 384 HIS C C    1 
ATOM   4380  O  O    . HIS C 1 177 ? 41.384  -26.218 0.331   1.00 61.63  ? 384 HIS C O    1 
ATOM   4381  C  CB   . HIS C 1 177 ? 42.961  -28.485 -0.576  1.00 63.38  ? 384 HIS C CB   1 
ATOM   4382  C  CG   . HIS C 1 177 ? 43.003  -29.766 -1.342  1.00 66.22  ? 384 HIS C CG   1 
ATOM   4383  N  ND1  . HIS C 1 177 ? 44.181  -30.330 -1.783  1.00 68.76  ? 384 HIS C ND1  1 
ATOM   4384  C  CD2  . HIS C 1 177 ? 42.016  -30.595 -1.746  1.00 66.27  ? 384 HIS C CD2  1 
ATOM   4385  C  CE1  . HIS C 1 177 ? 43.918  -31.454 -2.422  1.00 66.74  ? 384 HIS C CE1  1 
ATOM   4386  N  NE2  . HIS C 1 177 ? 42.611  -31.636 -2.415  1.00 64.89  ? 384 HIS C NE2  1 
ATOM   4387  N  N    . GLY C 1 178 ? 42.934  -24.955 -0.713  1.00 57.77  ? 385 GLY C N    1 
ATOM   4388  C  CA   . GLY C 1 178 ? 42.715  -23.883 0.212   1.00 56.04  ? 385 GLY C CA   1 
ATOM   4389  C  C    . GLY C 1 178 ? 43.130  -24.271 1.631   1.00 60.82  ? 385 GLY C C    1 
ATOM   4390  O  O    . GLY C 1 178 ? 43.781  -25.286 1.882   1.00 64.40  ? 385 GLY C O    1 
ATOM   4391  N  N    . LEU C 1 179 ? 42.721  -23.423 2.568   1.00 57.42  ? 386 LEU C N    1 
ATOM   4392  C  CA   . LEU C 1 179 ? 43.113  -23.609 3.956   1.00 56.89  ? 386 LEU C CA   1 
ATOM   4393  C  C    . LEU C 1 179 ? 42.448  -24.853 4.526   1.00 55.60  ? 386 LEU C C    1 
ATOM   4394  O  O    . LEU C 1 179 ? 41.267  -25.097 4.295   1.00 64.87  ? 386 LEU C O    1 
ATOM   4395  C  CB   . LEU C 1 179 ? 42.754  -22.368 4.774   1.00 60.89  ? 386 LEU C CB   1 
ATOM   4396  C  CG   . LEU C 1 179 ? 43.720  -21.156 4.771   1.00 61.92  ? 386 LEU C CG   1 
ATOM   4397  C  CD1  . LEU C 1 179 ? 44.451  -20.912 3.435   1.00 60.07  ? 386 LEU C CD1  1 
ATOM   4398  C  CD2  . LEU C 1 179 ? 42.973  -19.887 5.198   1.00 60.60  ? 386 LEU C CD2  1 
ATOM   4399  N  N    . GLN C 1 180 ? 43.217  -25.651 5.267   1.00 57.21  ? 387 GLN C N    1 
ATOM   4400  C  CA   . GLN C 1 180 ? 42.817  -27.002 5.645   1.00 57.45  ? 387 GLN C CA   1 
ATOM   4401  C  C    . GLN C 1 180 ? 43.267  -27.322 7.059   1.00 62.07  ? 387 GLN C C    1 
ATOM   4402  O  O    . GLN C 1 180 ? 44.373  -26.957 7.465   1.00 64.42  ? 387 GLN C O    1 
ATOM   4403  C  CB   . GLN C 1 180 ? 43.443  -28.047 4.709   1.00 63.61  ? 387 GLN C CB   1 
ATOM   4404  C  CG   . GLN C 1 180 ? 42.892  -28.056 3.307   1.00 61.95  ? 387 GLN C CG   1 
ATOM   4405  C  CD   . GLN C 1 180 ? 41.520  -28.678 3.255   1.00 62.32  ? 387 GLN C CD   1 
ATOM   4406  O  OE1  . GLN C 1 180 ? 41.112  -29.413 4.165   1.00 53.95  ? 387 GLN C OE1  1 
ATOM   4407  N  NE2  . GLN C 1 180 ? 40.785  -28.366 2.200   1.00 57.29  ? 387 GLN C NE2  1 
ATOM   4408  N  N    . GLU C 1 181 ? 42.436  -28.046 7.793   1.00 61.45  ? 388 GLU C N    1 
ATOM   4409  C  CA   . GLU C 1 181 ? 42.893  -28.581 9.062   1.00 65.46  ? 388 GLU C CA   1 
ATOM   4410  C  C    . GLU C 1 181 ? 44.023  -29.569 8.803   1.00 68.36  ? 388 GLU C C    1 
ATOM   4411  O  O    . GLU C 1 181 ? 43.889  -30.474 7.973   1.00 61.39  ? 388 GLU C O    1 
ATOM   4412  C  CB   . GLU C 1 181 ? 41.743  -29.261 9.797   1.00 68.06  ? 388 GLU C CB   1 
ATOM   4413  C  CG   . GLU C 1 181 ? 40.624  -28.316 10.200  1.00 72.33  ? 388 GLU C CG   1 
ATOM   4414  C  CD   . GLU C 1 181 ? 39.682  -28.948 11.203  1.00 83.28  ? 388 GLU C CD   1 
ATOM   4415  O  OE1  . GLU C 1 181 ? 39.864  -30.150 11.508  1.00 81.90  ? 388 GLU C OE1  1 
ATOM   4416  O  OE2  . GLU C 1 181 ? 38.765  -28.247 11.689  1.00 94.06  ? 388 GLU C OE2  1 
ATOM   4417  N  N    . ALA C 1 182 ? 45.100  -29.394 9.559   1.00 67.57  ? 389 ALA C N    1 
ATOM   4418  C  CA   . ALA C 1 182 ? 46.276  -30.251 9.343   1.00 63.50  ? 389 ALA C CA   1 
ATOM   4419  C  C    . ALA C 1 182 ? 46.925  -30.693 10.647  1.00 65.45  ? 389 ALA C C    1 
ATOM   4420  O  O    . ALA C 1 182 ? 46.459  -30.298 11.721  1.00 65.93  ? 389 ALA C O    1 
ATOM   4421  C  CB   . ALA C 1 182 ? 47.272  -29.496 8.518   1.00 61.73  ? 389 ALA C CB   1 
ATOM   4422  N  N    . GLU C 1 183 ? 47.952  -31.522 10.523  1.00 63.03  ? 390 GLU C N    1 
ATOM   4423  C  CA   . GLU C 1 183 ? 48.732  -31.980 11.683  1.00 56.96  ? 390 GLU C CA   1 
ATOM   4424  C  C    . GLU C 1 183 ? 50.187  -31.685 11.335  1.00 57.84  ? 390 GLU C C    1 
ATOM   4425  O  O    . GLU C 1 183 ? 50.601  -32.032 10.229  1.00 59.10  ? 390 GLU C O    1 
ATOM   4426  C  CB   . GLU C 1 183 ? 48.540  -33.476 11.858  1.00 64.46  ? 390 GLU C CB   1 
ATOM   4427  C  CG   . GLU C 1 183 ? 47.690  -33.879 13.037  1.00 67.11  ? 390 GLU C CG   1 
ATOM   4428  C  CD   . GLU C 1 183 ? 47.558  -35.385 13.192  1.00 71.24  ? 390 GLU C CD   1 
ATOM   4429  O  OE1  . GLU C 1 183 ? 47.858  -36.109 12.225  1.00 73.47  ? 390 GLU C OE1  1 
ATOM   4430  O  OE2  . GLU C 1 183 ? 47.148  -35.831 14.277  1.00 74.13  ? 390 GLU C OE2  1 
ATOM   4431  N  N    . LYS C 1 184 ? 50.916  -31.037 12.235  1.00 55.46  ? 391 LYS C N    1 
ATOM   4432  C  CA   . LYS C 1 184 ? 52.326  -30.678 11.977  1.00 47.29  ? 391 LYS C CA   1 
ATOM   4433  C  C    . LYS C 1 184 ? 53.220  -31.465 12.923  1.00 46.15  ? 391 LYS C C    1 
ATOM   4434  O  O    . LYS C 1 184 ? 52.809  -31.741 14.039  1.00 51.32  ? 391 LYS C O    1 
ATOM   4435  C  CB   . LYS C 1 184 ? 52.554  -29.176 12.133  1.00 51.76  ? 391 LYS C CB   1 
ATOM   4436  C  CG   . LYS C 1 184 ? 53.904  -28.655 11.660  1.00 57.20  ? 391 LYS C CG   1 
ATOM   4437  C  CD   . LYS C 1 184 ? 54.019  -27.153 11.710  1.00 56.33  ? 391 LYS C CD   1 
ATOM   4438  C  CE   . LYS C 1 184 ? 55.448  -26.669 11.603  1.00 59.62  ? 391 LYS C CE   1 
ATOM   4439  N  NZ   . LYS C 1 184 ? 56.107  -26.613 12.928  1.00 66.85  ? 391 LYS C NZ   1 
ATOM   4440  N  N    . GLY C 1 185 ? 54.410  -31.812 12.455  1.00 48.09  ? 392 GLY C N    1 
ATOM   4441  C  CA   . GLY C 1 185 ? 55.335  -32.540 13.303  1.00 50.30  ? 392 GLY C CA   1 
ATOM   4442  C  C    . GLY C 1 185 ? 56.793  -32.309 12.957  1.00 54.77  ? 392 GLY C C    1 
ATOM   4443  O  O    . GLY C 1 185 ? 57.169  -32.335 11.776  1.00 53.02  ? 392 GLY C O    1 
ATOM   4444  N  N    . VAL C 1 186 ? 57.637  -32.117 13.971  1.00 50.26  ? 393 VAL C N    1 
ATOM   4445  C  CA   . VAL C 1 186 ? 59.063  -31.883 13.766  1.00 50.62  ? 393 VAL C CA   1 
ATOM   4446  C  C    . VAL C 1 186 ? 59.828  -33.056 14.340  1.00 49.82  ? 393 VAL C C    1 
ATOM   4447  O  O    . VAL C 1 186 ? 59.447  -33.596 15.385  1.00 53.06  ? 393 VAL C O    1 
ATOM   4448  C  CB   . VAL C 1 186 ? 59.551  -30.568 14.408  1.00 53.60  ? 393 VAL C CB   1 
ATOM   4449  C  CG1  . VAL C 1 186 ? 61.086  -30.495 14.354  1.00 50.24  ? 393 VAL C CG1  1 
ATOM   4450  C  CG2  . VAL C 1 186 ? 58.928  -29.367 13.704  1.00 43.59  ? 393 VAL C CG2  1 
ATOM   4451  N  N    . LYS C 1 187 ? 60.893  -33.465 13.643  1.00 49.01  ? 394 LYS C N    1 
ATOM   4452  C  CA   . LYS C 1 187 ? 61.880  -34.384 14.198  1.00 49.66  ? 394 LYS C CA   1 
ATOM   4453  C  C    . LYS C 1 187 ? 63.242  -33.859 13.797  1.00 47.58  ? 394 LYS C C    1 
ATOM   4454  O  O    . LYS C 1 187 ? 63.363  -33.049 12.883  1.00 51.98  ? 394 LYS C O    1 
ATOM   4455  C  CB   . LYS C 1 187 ? 61.697  -35.837 13.703  1.00 50.70  ? 394 LYS C CB   1 
ATOM   4456  C  CG   . LYS C 1 187 ? 60.471  -36.547 14.248  1.00 50.24  ? 394 LYS C CG   1 
ATOM   4457  C  CD   . LYS C 1 187 ? 60.828  -37.462 15.414  1.00 56.53  ? 394 LYS C CD   1 
ATOM   4458  N  N    . PHE C 1 188 ? 64.275  -34.330 14.472  1.00 50.81  ? 395 PHE C N    1 
ATOM   4459  C  CA   . PHE C 1 188 ? 65.632  -33.924 14.135  1.00 50.58  ? 395 PHE C CA   1 
ATOM   4460  C  C    . PHE C 1 188 ? 66.198  -34.888 13.103  1.00 52.03  ? 395 PHE C C    1 
ATOM   4461  O  O    . PHE C 1 188 ? 66.073  -36.111 13.258  1.00 56.57  ? 395 PHE C O    1 
ATOM   4462  C  CB   . PHE C 1 188 ? 66.511  -33.890 15.391  1.00 46.09  ? 395 PHE C CB   1 
ATOM   4463  C  CG   . PHE C 1 188 ? 66.075  -32.866 16.380  1.00 45.47  ? 395 PHE C CG   1 
ATOM   4464  C  CD1  . PHE C 1 188 ? 65.099  -33.166 17.316  1.00 46.16  ? 395 PHE C CD1  1 
ATOM   4465  C  CD2  . PHE C 1 188 ? 66.600  -31.582 16.342  1.00 44.79  ? 395 PHE C CD2  1 
ATOM   4466  C  CE1  . PHE C 1 188 ? 64.666  -32.216 18.218  1.00 48.43  ? 395 PHE C CE1  1 
ATOM   4467  C  CE2  . PHE C 1 188 ? 66.163  -30.631 17.229  1.00 48.51  ? 395 PHE C CE2  1 
ATOM   4468  C  CZ   . PHE C 1 188 ? 65.183  -30.952 18.175  1.00 46.74  ? 395 PHE C CZ   1 
ATOM   4469  N  N    . LEU C 1 189 ? 66.808  -34.348 12.046  1.00 43.86  ? 396 LEU C N    1 
ATOM   4470  C  CA   . LEU C 1 189 ? 67.539  -35.248 11.168  1.00 46.88  ? 396 LEU C CA   1 
ATOM   4471  C  C    . LEU C 1 189 ? 68.940  -35.487 11.700  1.00 50.25  ? 396 LEU C C    1 
ATOM   4472  O  O    . LEU C 1 189 ? 69.415  -36.626 11.692  1.00 55.81  ? 396 LEU C O    1 
ATOM   4473  C  CB   . LEU C 1 189 ? 67.603  -34.700 9.753   1.00 50.40  ? 396 LEU C CB   1 
ATOM   4474  C  CG   . LEU C 1 189 ? 66.312  -34.644 8.957   1.00 52.34  ? 396 LEU C CG   1 
ATOM   4475  C  CD1  . LEU C 1 189 ? 66.636  -34.251 7.522   1.00 51.89  ? 396 LEU C CD1  1 
ATOM   4476  C  CD2  . LEU C 1 189 ? 65.608  -35.983 9.010   1.00 49.03  ? 396 LEU C CD2  1 
ATOM   4477  N  N    . THR C 1 190 ? 69.604  -34.424 12.164  1.00 46.06  ? 397 THR C N    1 
ATOM   4478  C  CA   . THR C 1 190 ? 70.902  -34.507 12.813  1.00 43.79  ? 397 THR C CA   1 
ATOM   4479  C  C    . THR C 1 190 ? 70.923  -33.607 14.036  1.00 49.54  ? 397 THR C C    1 
ATOM   4480  O  O    . THR C 1 190 ? 70.188  -32.617 14.119  1.00 50.58  ? 397 THR C O    1 
ATOM   4481  C  CB   . THR C 1 190 ? 72.062  -34.085 11.893  1.00 49.45  ? 397 THR C CB   1 
ATOM   4482  O  OG1  . THR C 1 190 ? 71.882  -32.718 11.481  1.00 46.96  ? 397 THR C OG1  1 
ATOM   4483  C  CG2  . THR C 1 190 ? 72.174  -35.007 10.662  1.00 40.23  ? 397 THR C CG2  1 
ATOM   4484  N  N    . LEU C 1 191 ? 71.776  -33.971 14.987  1.00 48.24  ? 398 LEU C N    1 
ATOM   4485  C  CA   . LEU C 1 191 ? 72.145  -33.197 16.141  1.00 42.89  ? 398 LEU C CA   1 
ATOM   4486  C  C    . LEU C 1 191 ? 73.627  -32.844 16.051  1.00 51.07  ? 398 LEU C C    1 
ATOM   4487  O  O    . LEU C 1 191 ? 74.445  -33.693 15.680  1.00 49.69  ? 398 LEU C O    1 
ATOM   4488  C  CB   . LEU C 1 191 ? 71.868  -33.973 17.413  1.00 46.83  ? 398 LEU C CB   1 
ATOM   4489  C  CG   . LEU C 1 191 ? 70.383  -34.197 17.674  1.00 52.46  ? 398 LEU C CG   1 
ATOM   4490  C  CD1  . LEU C 1 191 ? 70.193  -35.373 18.588  1.00 41.64  ? 398 LEU C CD1  1 
ATOM   4491  C  CD2  . LEU C 1 191 ? 69.739  -32.927 18.233  1.00 44.78  ? 398 LEU C CD2  1 
ATOM   4492  N  N    . PRO C 1 192 ? 74.003  -31.608 16.342  1.00 49.75  ? 399 PRO C N    1 
ATOM   4493  C  CA   . PRO C 1 192 ? 75.369  -31.171 16.040  1.00 50.93  ? 399 PRO C CA   1 
ATOM   4494  C  C    . PRO C 1 192 ? 76.364  -31.715 17.049  1.00 45.63  ? 399 PRO C C    1 
ATOM   4495  O  O    . PRO C 1 192 ? 75.970  -32.235 18.103  1.00 48.20  ? 399 PRO C O    1 
ATOM   4496  C  CB   . PRO C 1 192 ? 75.273  -29.634 16.103  1.00 47.87  ? 399 PRO C CB   1 
ATOM   4497  C  CG   . PRO C 1 192 ? 74.134  -29.372 17.015  1.00 49.68  ? 399 PRO C CG   1 
ATOM   4498  C  CD   . PRO C 1 192 ? 73.137  -30.492 16.756  1.00 45.38  ? 399 PRO C CD   1 
ATOM   4499  N  N    . PRO C 1 193 ? 77.670  -31.639 16.743  1.00 48.39  ? 400 PRO C N    1 
ATOM   4500  C  CA   . PRO C 1 193 ? 78.688  -31.985 17.757  1.00 51.11  ? 400 PRO C CA   1 
ATOM   4501  C  C    . PRO C 1 193 ? 78.573  -31.166 19.034  1.00 54.06  ? 400 PRO C C    1 
ATOM   4502  O  O    . PRO C 1 193 ? 78.805  -31.682 20.137  1.00 50.66  ? 400 PRO C O    1 
ATOM   4503  C  CB   . PRO C 1 193 ? 80.010  -31.698 17.031  1.00 53.00  ? 400 PRO C CB   1 
ATOM   4504  C  CG   . PRO C 1 193 ? 79.683  -31.847 15.567  1.00 47.17  ? 400 PRO C CG   1 
ATOM   4505  C  CD   . PRO C 1 193 ? 78.266  -31.372 15.418  1.00 46.12  ? 400 PRO C CD   1 
ATOM   4506  N  N    . VAL C 1 194 ? 78.228  -29.890 18.902  1.00 54.19  ? 401 VAL C N    1 
ATOM   4507  C  CA   . VAL C 1 194 ? 78.064  -28.977 20.025  1.00 50.89  ? 401 VAL C CA   1 
ATOM   4508  C  C    . VAL C 1 194 ? 76.628  -28.472 20.001  1.00 51.26  ? 401 VAL C C    1 
ATOM   4509  O  O    . VAL C 1 194 ? 76.211  -27.815 19.039  1.00 50.88  ? 401 VAL C O    1 
ATOM   4510  C  CB   . VAL C 1 194 ? 79.061  -27.812 19.947  1.00 52.81  ? 401 VAL C CB   1 
ATOM   4511  C  CG1  . VAL C 1 194 ? 78.928  -26.909 21.151  1.00 44.08  ? 401 VAL C CG1  1 
ATOM   4512  C  CG2  . VAL C 1 194 ? 80.493  -28.357 19.795  1.00 54.52  ? 401 VAL C CG2  1 
ATOM   4513  N  N    . LEU C 1 195 ? 75.885  -28.856 21.039  1.00 49.31  ? 402 LEU C N    1 
ATOM   4514  C  CA   . LEU C 1 195 ? 74.440  -28.568 21.111  1.00 49.01  ? 402 LEU C CA   1 
ATOM   4515  C  C    . LEU C 1 195 ? 74.161  -27.392 22.022  1.00 49.31  ? 402 LEU C C    1 
ATOM   4516  O  O    . LEU C 1 195 ? 74.414  -27.503 23.218  1.00 54.92  ? 402 LEU C O    1 
ATOM   4517  C  CB   . LEU C 1 195 ? 73.768  -29.823 21.663  1.00 49.88  ? 402 LEU C CB   1 
ATOM   4518  C  CG   . LEU C 1 195 ? 72.252  -29.891 21.557  1.00 47.35  ? 402 LEU C CG   1 
ATOM   4519  C  CD1  . LEU C 1 195 ? 71.804  -29.786 20.114  1.00 51.24  ? 402 LEU C CD1  1 
ATOM   4520  C  CD2  . LEU C 1 195 ? 71.755  -31.181 22.171  1.00 48.80  ? 402 LEU C CD2  1 
ATOM   4521  N  N    . HIS C 1 196 ? 73.667  -26.312 21.451  1.00 46.91  ? 403 HIS C N    1 
ATOM   4522  C  CA   . HIS C 1 196 ? 73.248  -25.151 22.222  1.00 46.30  ? 403 HIS C CA   1 
ATOM   4523  C  C    . HIS C 1 196 ? 71.748  -25.227 22.454  1.00 49.71  ? 403 HIS C C    1 
ATOM   4524  O  O    . HIS C 1 196 ? 70.974  -25.178 21.493  1.00 53.56  ? 403 HIS C O    1 
ATOM   4525  C  CB   . HIS C 1 196 ? 73.579  -23.851 21.495  1.00 52.91  ? 403 HIS C CB   1 
ATOM   4526  C  CG   . HIS C 1 196 ? 75.008  -23.414 21.616  1.00 52.22  ? 403 HIS C CG   1 
ATOM   4527  N  ND1  . HIS C 1 196 ? 75.961  -24.141 22.296  1.00 51.67  ? 403 HIS C ND1  1 
ATOM   4528  C  CD2  . HIS C 1 196 ? 75.649  -22.327 21.113  1.00 49.47  ? 403 HIS C CD2  1 
ATOM   4529  C  CE1  . HIS C 1 196 ? 77.123  -23.510 22.226  1.00 51.57  ? 403 HIS C CE1  1 
ATOM   4530  N  NE2  . HIS C 1 196 ? 76.962  -22.411 21.510  1.00 46.31  ? 403 HIS C NE2  1 
ATOM   4531  N  N    . LEU C 1 197 ? 71.331  -25.314 23.717  1.00 42.96  ? 404 LEU C N    1 
ATOM   4532  C  CA   . LEU C 1 197 ? 69.917  -25.399 24.067  1.00 48.58  ? 404 LEU C CA   1 
ATOM   4533  C  C    . LEU C 1 197 ? 69.486  -24.109 24.760  1.00 52.64  ? 404 LEU C C    1 
ATOM   4534  O  O    . LEU C 1 197 ? 70.032  -23.754 25.809  1.00 54.21  ? 404 LEU C O    1 
ATOM   4535  C  CB   . LEU C 1 197 ? 69.653  -26.612 24.961  1.00 46.62  ? 404 LEU C CB   1 
ATOM   4536  C  CG   . LEU C 1 197 ? 70.106  -27.961 24.368  1.00 50.67  ? 404 LEU C CG   1 
ATOM   4537  C  CD1  . LEU C 1 197 ? 69.904  -29.096 25.377  1.00 43.43  ? 404 LEU C CD1  1 
ATOM   4538  C  CD2  . LEU C 1 197 ? 69.398  -28.263 23.051  1.00 44.53  ? 404 LEU C CD2  1 
ATOM   4539  N  N    . GLN C 1 198 ? 68.513  -23.401 24.182  1.00 44.89  ? 405 GLN C N    1 
ATOM   4540  C  CA   . GLN C 1 198 ? 67.972  -22.161 24.793  1.00 43.80  ? 405 GLN C CA   1 
ATOM   4541  C  C    . GLN C 1 198 ? 66.676  -22.486 25.528  1.00 53.62  ? 405 GLN C C    1 
ATOM   4542  O  O    . GLN C 1 198 ? 65.734  -22.951 24.893  1.00 54.96  ? 405 GLN C O    1 
ATOM   4543  C  CB   . GLN C 1 198 ? 67.702  -21.086 23.748  1.00 41.85  ? 405 GLN C CB   1 
ATOM   4544  C  CG   . GLN C 1 198 ? 67.296  -19.750 24.348  1.00 47.76  ? 405 GLN C CG   1 
ATOM   4545  C  CD   . GLN C 1 198 ? 66.761  -18.791 23.315  1.00 50.20  ? 405 GLN C CD   1 
ATOM   4546  O  OE1  . GLN C 1 198 ? 66.606  -19.126 22.146  1.00 51.26  ? 405 GLN C OE1  1 
ATOM   4547  N  NE2  . GLN C 1 198 ? 66.490  -17.571 23.740  1.00 51.93  ? 405 GLN C NE2  1 
ATOM   4548  N  N    . LEU C 1 199 ? 66.643  -22.226 26.829  1.00 54.27  ? 406 LEU C N    1 
ATOM   4549  C  CA   . LEU C 1 199 ? 65.455  -22.556 27.642  1.00 50.25  ? 406 LEU C CA   1 
ATOM   4550  C  C    . LEU C 1 199 ? 64.518  -21.352 27.647  1.00 52.99  ? 406 LEU C C    1 
ATOM   4551  O  O    . LEU C 1 199 ? 64.944  -20.282 28.071  1.00 43.69  ? 406 LEU C O    1 
ATOM   4552  C  CB   . LEU C 1 199 ? 65.917  -22.963 29.042  1.00 52.57  ? 406 LEU C CB   1 
ATOM   4553  C  CG   . LEU C 1 199 ? 66.941  -24.095 29.095  1.00 57.89  ? 406 LEU C CG   1 
ATOM   4554  C  CD1  . LEU C 1 199 ? 67.304  -24.429 30.530  1.00 48.97  ? 406 LEU C CD1  1 
ATOM   4555  C  CD2  . LEU C 1 199 ? 66.431  -25.329 28.375  1.00 52.86  ? 406 LEU C CD2  1 
ATOM   4556  N  N    . MET C 1 200 ? 63.286  -21.552 27.189  1.00 56.61  ? 407 MET C N    1 
ATOM   4557  C  CA   . MET C 1 200 ? 62.295  -20.458 27.062  1.00 57.19  ? 407 MET C CA   1 
ATOM   4558  C  C    . MET C 1 200 ? 61.712  -20.082 28.426  1.00 58.71  ? 407 MET C C    1 
ATOM   4559  O  O    . MET C 1 200 ? 60.552  -20.427 28.690  1.00 53.80  ? 407 MET C O    1 
ATOM   4560  C  CB   . MET C 1 200 ? 61.185  -20.907 26.112  1.00 55.74  ? 407 MET C CB   1 
ATOM   4561  C  CG   . MET C 1 200 ? 61.697  -21.383 24.777  1.00 55.28  ? 407 MET C CG   1 
ATOM   4562  S  SD   . MET C 1 200 ? 61.985  -20.012 23.660  1.00 69.16  ? 407 MET C SD   1 
ATOM   4563  C  CE   . MET C 1 200 ? 60.376  -19.901 22.883  1.00 54.76  ? 407 MET C CE   1 
ATOM   4564  N  N    . ARG C 1 201 ? 62.496  -19.369 29.229  1.00 59.32  ? 408 ARG C N    1 
ATOM   4565  C  CA   . ARG C 1 201 ? 62.060  -18.936 30.573  1.00 56.02  ? 408 ARG C CA   1 
ATOM   4566  C  C    . ARG C 1 201 ? 61.446  -17.543 30.464  1.00 57.00  ? 408 ARG C C    1 
ATOM   4567  O  O    . ARG C 1 201 ? 61.895  -16.652 31.178  1.00 58.87  ? 408 ARG C O    1 
ATOM   4568  C  CB   . ARG C 1 201 ? 63.270  -18.987 31.500  1.00 59.62  ? 408 ARG C CB   1 
ATOM   4569  C  CG   . ARG C 1 201 ? 63.823  -20.387 31.712  1.00 61.13  ? 408 ARG C CG   1 
ATOM   4570  C  CD   . ARG C 1 201 ? 64.720  -20.390 32.928  1.00 61.65  ? 408 ARG C CD   1 
ATOM   4571  N  NE   . ARG C 1 201 ? 65.025  -21.701 33.481  1.00 66.84  ? 408 ARG C NE   1 
ATOM   4572  C  CZ   . ARG C 1 201 ? 64.355  -22.287 34.465  1.00 62.11  ? 408 ARG C CZ   1 
ATOM   4573  N  NH1  . ARG C 1 201 ? 63.315  -21.688 35.015  1.00 54.47  ? 408 ARG C NH1  1 
ATOM   4574  N  NH2  . ARG C 1 201 ? 64.729  -23.475 34.899  1.00 65.44  ? 408 ARG C NH2  1 
ATOM   4575  N  N    . PHE C 1 202 ? 60.475  -17.380 29.571  1.00 55.98  ? 409 PHE C N    1 
ATOM   4576  C  CA   . PHE C 1 202 ? 59.760  -16.091 29.414  1.00 58.26  ? 409 PHE C CA   1 
ATOM   4577  C  C    . PHE C 1 202 ? 58.333  -16.353 28.918  1.00 62.15  ? 409 PHE C C    1 
ATOM   4578  O  O    . PHE C 1 202 ? 58.118  -17.345 28.210  1.00 64.02  ? 409 PHE C O    1 
ATOM   4579  C  CB   . PHE C 1 202 ? 60.509  -15.133 28.486  1.00 62.46  ? 409 PHE C CB   1 
ATOM   4580  C  CG   . PHE C 1 202 ? 61.460  -15.727 27.482  1.00 61.25  ? 409 PHE C CG   1 
ATOM   4581  C  CD1  . PHE C 1 202 ? 60.997  -16.473 26.412  1.00 63.01  ? 409 PHE C CD1  1 
ATOM   4582  C  CD2  . PHE C 1 202 ? 62.819  -15.487 27.581  1.00 58.67  ? 409 PHE C CD2  1 
ATOM   4583  C  CE1  . PHE C 1 202 ? 61.880  -16.997 25.485  1.00 60.99  ? 409 PHE C CE1  1 
ATOM   4584  C  CE2  . PHE C 1 202 ? 63.699  -16.009 26.649  1.00 61.43  ? 409 PHE C CE2  1 
ATOM   4585  C  CZ   . PHE C 1 202 ? 63.229  -16.767 25.605  1.00 59.98  ? 409 PHE C CZ   1 
ATOM   4586  N  N    . MET C 1 203 ? 57.392  -15.483 29.279  1.00 58.28  ? 410 MET C N    1 
ATOM   4587  C  CA   . MET C 1 203 ? 55.970  -15.645 28.877  1.00 66.58  ? 410 MET C CA   1 
ATOM   4588  C  C    . MET C 1 203 ? 55.267  -14.279 28.829  1.00 69.63  ? 410 MET C C    1 
ATOM   4589  O  O    . MET C 1 203 ? 55.875  -13.292 29.252  1.00 65.76  ? 410 MET C O    1 
ATOM   4590  C  CB   . MET C 1 203 ? 55.246  -16.574 29.854  1.00 67.96  ? 410 MET C CB   1 
ATOM   4591  C  CG   . MET C 1 203 ? 55.091  -16.032 31.256  1.00 65.68  ? 410 MET C CG   1 
ATOM   4592  S  SD   . MET C 1 203 ? 54.367  -17.256 32.379  1.00 86.84  ? 410 MET C SD   1 
ATOM   4593  C  CE   . MET C 1 203 ? 53.555  -18.358 31.224  1.00 73.72  ? 410 MET C CE   1 
ATOM   4594  N  N    . TYR C 1 204 ? 54.030  -14.230 28.317  1.00 73.17  ? 411 TYR C N    1 
ATOM   4595  C  CA   . TYR C 1 204 ? 53.292  -12.970 28.223  1.00 80.13  ? 411 TYR C CA   1 
ATOM   4596  C  C    . TYR C 1 204 ? 52.164  -12.930 29.236  1.00 79.75  ? 411 TYR C C    1 
ATOM   4597  O  O    . TYR C 1 204 ? 51.669  -11.857 29.571  1.00 84.96  ? 411 TYR C O    1 
ATOM   4598  C  CB   . TYR C 1 204 ? 52.729  -12.763 26.813  1.00 85.65  ? 411 TYR C CB   1 
ATOM   4599  N  N    . THR C 1 208 ? 48.275  -8.392  32.587  1.00 90.34  ? 415 THR C N    1 
ATOM   4600  C  CA   . THR C 1 208 ? 49.082  -7.149  32.443  1.00 84.86  ? 415 THR C CA   1 
ATOM   4601  C  C    . THR C 1 208 ? 49.376  -6.925  30.962  1.00 83.29  ? 415 THR C C    1 
ATOM   4602  O  O    . THR C 1 208 ? 48.591  -7.404  30.127  1.00 93.19  ? 415 THR C O    1 
ATOM   4603  C  CB   . THR C 1 208 ? 50.384  -7.183  33.262  1.00 86.82  ? 415 THR C CB   1 
ATOM   4604  O  OG1  . THR C 1 208 ? 50.442  -8.350  34.086  1.00 91.43  ? 415 THR C OG1  1 
ATOM   4605  C  CG2  . THR C 1 208 ? 50.558  -5.966  34.144  1.00 76.13  ? 415 THR C CG2  1 
ATOM   4606  N  N    . ASP C 1 209 ? 50.449  -6.205  30.654  1.00 84.17  ? 416 ASP C N    1 
ATOM   4607  C  CA   . ASP C 1 209 ? 50.857  -6.013  29.240  1.00 82.13  ? 416 ASP C CA   1 
ATOM   4608  C  C    . ASP C 1 209 ? 52.374  -6.146  29.176  1.00 82.58  ? 416 ASP C C    1 
ATOM   4609  O  O    . ASP C 1 209 ? 52.986  -5.395  28.402  1.00 92.38  ? 416 ASP C O    1 
ATOM   4610  N  N    . GLN C 1 210 ? 52.948  -7.064  29.959  1.00 82.78  ? 417 GLN C N    1 
ATOM   4611  C  CA   . GLN C 1 210 ? 54.404  -7.183  30.024  1.00 80.95  ? 417 GLN C CA   1 
ATOM   4612  C  C    . GLN C 1 210 ? 54.815  -8.658  30.023  1.00 81.50  ? 417 GLN C C    1 
ATOM   4613  O  O    . GLN C 1 210 ? 53.987  -9.562  30.172  1.00 81.84  ? 417 GLN C O    1 
ATOM   4614  N  N    . ASN C 1 211 ? 56.112  -8.903  29.843  1.00 75.82  ? 418 ASN C N    1 
ATOM   4615  C  CA   . ASN C 1 211 ? 56.661  -10.254 29.803  1.00 69.53  ? 418 ASN C CA   1 
ATOM   4616  C  C    . ASN C 1 211 ? 57.523  -10.487 31.038  1.00 71.39  ? 418 ASN C C    1 
ATOM   4617  O  O    . ASN C 1 211 ? 58.298  -9.613  31.430  1.00 66.87  ? 418 ASN C O    1 
ATOM   4618  N  N    . ILE C 1 212 ? 57.400  -11.666 31.651  1.00 69.76  ? 419 ILE C N    1 
ATOM   4619  C  CA   . ILE C 1 212 ? 58.117  -11.958 32.888  1.00 71.24  ? 419 ILE C CA   1 
ATOM   4620  C  C    . ILE C 1 212 ? 58.979  -13.204 32.720  1.00 66.72  ? 419 ILE C C    1 
ATOM   4621  O  O    . ILE C 1 212 ? 58.715  -14.071 31.885  1.00 64.40  ? 419 ILE C O    1 
ATOM   4622  C  CB   . ILE C 1 212 ? 57.163  -12.126 34.085  1.00 65.47  ? 419 ILE C CB   1 
ATOM   4623  C  CG1  . ILE C 1 212 ? 56.233  -13.324 33.867  1.00 67.44  ? 419 ILE C CG1  1 
ATOM   4624  C  CG2  . ILE C 1 212 ? 56.373  -10.851 34.290  1.00 62.51  ? 419 ILE C CG2  1 
ATOM   4625  C  CD1  . ILE C 1 212 ? 55.873  -14.061 35.129  1.00 70.03  ? 419 ILE C CD1  1 
ATOM   4626  N  N    . LYS C 1 213 ? 60.020  -13.291 33.542  1.00 63.18  ? 420 LYS C N    1 
ATOM   4627  C  CA   . LYS C 1 213 ? 60.850  -14.484 33.537  1.00 59.68  ? 420 LYS C CA   1 
ATOM   4628  C  C    . LYS C 1 213 ? 60.109  -15.636 34.206  1.00 59.48  ? 420 LYS C C    1 
ATOM   4629  O  O    . LYS C 1 213 ? 59.322  -15.436 35.132  1.00 65.51  ? 420 LYS C O    1 
ATOM   4630  C  CB   . LYS C 1 213 ? 62.187  -14.215 34.232  1.00 62.16  ? 420 LYS C CB   1 
ATOM   4631  C  CG   . LYS C 1 213 ? 62.997  -15.473 34.553  1.00 60.61  ? 420 LYS C CG   1 
ATOM   4632  C  CD   . LYS C 1 213 ? 64.396  -15.162 35.066  1.00 58.71  ? 420 LYS C CD   1 
ATOM   4633  C  CE   . LYS C 1 213 ? 65.260  -16.390 34.896  1.00 58.21  ? 420 LYS C CE   1 
ATOM   4634  N  NZ   . LYS C 1 213 ? 66.471  -16.494 35.753  1.00 55.32  ? 420 LYS C NZ   1 
ATOM   4635  N  N    . ILE C 1 214 ? 60.323  -16.841 33.694  1.00 56.77  ? 421 ILE C N    1 
ATOM   4636  C  CA   . ILE C 1 214 ? 59.869  -18.069 34.332  1.00 58.58  ? 421 ILE C CA   1 
ATOM   4637  C  C    . ILE C 1 214 ? 61.030  -18.657 35.113  1.00 59.84  ? 421 ILE C C    1 
ATOM   4638  O  O    . ILE C 1 214 ? 62.113  -18.872 34.551  1.00 57.92  ? 421 ILE C O    1 
ATOM   4639  C  CB   . ILE C 1 214 ? 59.363  -19.084 33.295  1.00 55.91  ? 421 ILE C CB   1 
ATOM   4640  C  CG1  . ILE C 1 214 ? 58.253  -18.440 32.455  1.00 60.00  ? 421 ILE C CG1  1 
ATOM   4641  C  CG2  . ILE C 1 214 ? 58.909  -20.349 33.988  1.00 38.19  ? 421 ILE C CG2  1 
ATOM   4642  C  CD1  . ILE C 1 214 ? 57.958  -19.162 31.188  1.00 55.77  ? 421 ILE C CD1  1 
ATOM   4643  N  N    . ASN C 1 215 ? 60.790  -18.919 36.400  1.00 59.22  ? 422 ASN C N    1 
ATOM   4644  C  CA   . ASN C 1 215 ? 61.837  -19.470 37.296  1.00 58.31  ? 422 ASN C CA   1 
ATOM   4645  C  C    . ASN C 1 215 ? 61.400  -20.837 37.822  1.00 56.43  ? 422 ASN C C    1 
ATOM   4646  O  O    . ASN C 1 215 ? 61.868  -21.223 38.894  1.00 56.73  ? 422 ASN C O    1 
ATOM   4647  C  CB   . ASN C 1 215 ? 62.109  -18.515 38.456  1.00 58.83  ? 422 ASN C CB   1 
ATOM   4648  C  CG   . ASN C 1 215 ? 62.327  -17.082 38.030  1.00 62.93  ? 422 ASN C CG   1 
ATOM   4649  O  OD1  . ASN C 1 215 ? 63.436  -16.711 37.674  1.00 62.29  ? 422 ASN C OD1  1 
ATOM   4650  N  ND2  . ASN C 1 215 ? 61.286  -16.268 38.085  1.00 59.81  ? 422 ASN C ND2  1 
ATOM   4651  N  N    . ASP C 1 216 ? 60.562  -21.550 37.076  1.00 51.32  ? 423 ASP C N    1 
ATOM   4652  C  CA   . ASP C 1 216 ? 60.036  -22.871 37.503  1.00 52.48  ? 423 ASP C CA   1 
ATOM   4653  C  C    . ASP C 1 216 ? 61.138  -23.935 37.560  1.00 54.13  ? 423 ASP C C    1 
ATOM   4654  O  O    . ASP C 1 216 ? 62.203  -23.734 36.963  1.00 60.70  ? 423 ASP C O    1 
ATOM   4655  C  CB   . ASP C 1 216 ? 58.909  -23.319 36.572  1.00 54.27  ? 423 ASP C CB   1 
ATOM   4656  C  CG   . ASP C 1 216 ? 57.627  -22.510 36.673  1.00 59.22  ? 423 ASP C CG   1 
ATOM   4657  O  OD1  . ASP C 1 216 ? 57.664  -21.399 37.232  1.00 57.04  ? 423 ASP C OD1  1 
ATOM   4658  O  OD2  . ASP C 1 216 ? 56.600  -22.998 36.176  1.00 62.84  ? 423 ASP C OD2  1 
ATOM   4659  N  N    . ARG C 1 217 ? 60.862  -25.050 38.235  1.00 57.23  ? 424 ARG C N    1 
ATOM   4660  C  CA   . ARG C 1 217 ? 61.846  -26.155 38.345  1.00 55.54  ? 424 ARG C CA   1 
ATOM   4661  C  C    . ARG C 1 217 ? 61.933  -26.890 37.016  1.00 60.86  ? 424 ARG C C    1 
ATOM   4662  O  O    . ARG C 1 217 ? 60.905  -27.392 36.547  1.00 65.44  ? 424 ARG C O    1 
ATOM   4663  C  CB   . ARG C 1 217 ? 61.481  -27.134 39.459  1.00 51.07  ? 424 ARG C CB   1 
ATOM   4664  N  N    . PHE C 1 218 ? 63.133  -26.939 36.453  1.00 63.27  ? 425 PHE C N    1 
ATOM   4665  C  CA   . PHE C 1 218 ? 63.342  -27.595 35.173  1.00 57.87  ? 425 PHE C CA   1 
ATOM   4666  C  C    . PHE C 1 218 ? 64.622  -28.420 35.260  1.00 60.65  ? 425 PHE C C    1 
ATOM   4667  O  O    . PHE C 1 218 ? 65.726  -27.864 35.332  1.00 59.39  ? 425 PHE C O    1 
ATOM   4668  C  CB   . PHE C 1 218 ? 63.406  -26.570 34.050  1.00 57.62  ? 425 PHE C CB   1 
ATOM   4669  C  CG   . PHE C 1 218 ? 63.596  -27.191 32.718  1.00 61.29  ? 425 PHE C CG   1 
ATOM   4670  C  CD1  . PHE C 1 218 ? 62.530  -27.798 32.069  1.00 58.63  ? 425 PHE C CD1  1 
ATOM   4671  C  CD2  . PHE C 1 218 ? 64.853  -27.218 32.130  1.00 55.77  ? 425 PHE C CD2  1 
ATOM   4672  C  CE1  . PHE C 1 218 ? 62.718  -28.398 30.851  1.00 59.79  ? 425 PHE C CE1  1 
ATOM   4673  C  CE2  . PHE C 1 218 ? 65.038  -27.810 30.911  1.00 59.93  ? 425 PHE C CE2  1 
ATOM   4674  C  CZ   . PHE C 1 218 ? 63.976  -28.397 30.266  1.00 55.55  ? 425 PHE C CZ   1 
ATOM   4675  N  N    . GLU C 1 219 ? 64.466  -29.744 35.268  1.00 61.33  ? 426 GLU C N    1 
ATOM   4676  C  CA   . GLU C 1 219 ? 65.559  -30.670 35.508  1.00 57.95  ? 426 GLU C CA   1 
ATOM   4677  C  C    . GLU C 1 219 ? 66.268  -31.025 34.213  1.00 60.50  ? 426 GLU C C    1 
ATOM   4678  O  O    . GLU C 1 219 ? 65.623  -31.289 33.194  1.00 59.77  ? 426 GLU C O    1 
ATOM   4679  C  CB   . GLU C 1 219 ? 65.032  -31.941 36.155  1.00 59.50  ? 426 GLU C CB   1 
ATOM   4680  C  CG   . GLU C 1 219 ? 64.330  -31.711 37.473  1.00 59.26  ? 426 GLU C CG   1 
ATOM   4681  C  CD   . GLU C 1 219 ? 63.680  -32.973 37.969  1.00 57.47  ? 426 GLU C CD   1 
ATOM   4682  O  OE1  . GLU C 1 219 ? 63.785  -33.991 37.264  1.00 62.81  ? 426 GLU C OE1  1 
ATOM   4683  O  OE2  . GLU C 1 219 ? 63.061  -32.970 39.051  1.00 68.17  ? 426 GLU C OE2  1 
ATOM   4684  N  N    . PHE C 1 220 ? 67.602  -31.049 34.264  1.00 61.11  ? 427 PHE C N    1 
ATOM   4685  C  CA   . PHE C 1 220 ? 68.396  -31.444 33.112  1.00 59.89  ? 427 PHE C CA   1 
ATOM   4686  C  C    . PHE C 1 220 ? 69.570  -32.306 33.553  1.00 62.41  ? 427 PHE C C    1 
ATOM   4687  O  O    . PHE C 1 220 ? 70.160  -32.065 34.619  1.00 62.71  ? 427 PHE C O    1 
ATOM   4688  C  CB   . PHE C 1 220 ? 68.916  -30.238 32.306  1.00 60.38  ? 427 PHE C CB   1 
ATOM   4689  C  CG   . PHE C 1 220 ? 69.699  -29.227 33.106  1.00 56.78  ? 427 PHE C CG   1 
ATOM   4690  C  CD1  . PHE C 1 220 ? 71.040  -29.411 33.364  1.00 58.04  ? 427 PHE C CD1  1 
ATOM   4691  C  CD2  . PHE C 1 220 ? 69.102  -28.049 33.534  1.00 61.02  ? 427 PHE C CD2  1 
ATOM   4692  C  CE1  . PHE C 1 220 ? 71.774  -28.453 34.087  1.00 56.32  ? 427 PHE C CE1  1 
ATOM   4693  C  CE2  . PHE C 1 220 ? 69.831  -27.091 34.234  1.00 57.19  ? 427 PHE C CE2  1 
ATOM   4694  C  CZ   . PHE C 1 220 ? 71.166  -27.301 34.510  1.00 53.66  ? 427 PHE C CZ   1 
ATOM   4695  N  N    . PRO C 1 221 ? 69.955  -33.323 32.747  1.00 59.85  ? 428 PRO C N    1 
ATOM   4696  C  CA   . PRO C 1 221 ? 70.945  -34.236 33.220  1.00 56.32  ? 428 PRO C CA   1 
ATOM   4697  C  C    . PRO C 1 221 ? 72.392  -33.955 32.842  1.00 61.06  ? 428 PRO C C    1 
ATOM   4698  O  O    . PRO C 1 221 ? 72.680  -33.133 32.011  1.00 59.28  ? 428 PRO C O    1 
ATOM   4699  C  CB   . PRO C 1 221 ? 70.480  -35.534 32.550  1.00 59.96  ? 428 PRO C CB   1 
ATOM   4700  C  CG   . PRO C 1 221 ? 69.899  -35.135 31.222  1.00 61.25  ? 428 PRO C CG   1 
ATOM   4701  C  CD   . PRO C 1 221 ? 69.570  -33.674 31.349  1.00 56.76  ? 428 PRO C CD   1 
ATOM   4702  N  N    . GLU C 1 222 ? 73.270  -34.612 33.569  1.00 63.39  ? 429 GLU C N    1 
ATOM   4703  C  CA   . GLU C 1 222 ? 74.682  -34.544 33.210  1.00 62.89  ? 429 GLU C CA   1 
ATOM   4704  C  C    . GLU C 1 222 ? 74.947  -35.289 31.905  1.00 61.44  ? 429 GLU C C    1 
ATOM   4705  O  O    . GLU C 1 222 ? 75.892  -34.965 31.181  1.00 62.16  ? 429 GLU C O    1 
ATOM   4706  C  CB   . GLU C 1 222 ? 75.524  -35.110 34.355  1.00 58.85  ? 429 GLU C CB   1 
ATOM   4707  C  CG   . GLU C 1 222 ? 77.011  -35.156 34.101  1.00 63.64  ? 429 GLU C CG   1 
ATOM   4708  C  CD   . GLU C 1 222 ? 77.692  -36.304 34.837  1.00 66.72  ? 429 GLU C CD   1 
ATOM   4709  O  OE1  . GLU C 1 222 ? 78.198  -36.101 35.961  1.00 64.03  ? 429 GLU C OE1  1 
ATOM   4710  O  OE2  . GLU C 1 222 ? 77.726  -37.422 34.283  1.00 75.34  ? 429 GLU C OE2  1 
ATOM   4711  N  N    . GLN C 1 223 ? 74.118  -36.277 31.583  1.00 61.72  ? 430 GLN C N    1 
ATOM   4712  C  CA   . GLN C 1 223 ? 74.230  -37.022 30.339  1.00 62.66  ? 430 GLN C CA   1 
ATOM   4713  C  C    . GLN C 1 223 ? 72.875  -37.026 29.649  1.00 58.00  ? 430 GLN C C    1 
ATOM   4714  O  O    . GLN C 1 223 ? 71.850  -37.322 30.273  1.00 57.74  ? 430 GLN C O    1 
ATOM   4715  C  CB   . GLN C 1 223 ? 74.706  -38.455 30.583  1.00 66.63  ? 430 GLN C CB   1 
ATOM   4716  C  CG   . GLN C 1 223 ? 76.217  -38.619 30.601  1.00 68.66  ? 430 GLN C CG   1 
ATOM   4717  C  CD   . GLN C 1 223 ? 76.649  -39.691 31.585  1.00 82.34  ? 430 GLN C CD   1 
ATOM   4718  O  OE1  . GLN C 1 223 ? 76.095  -39.796 32.687  1.00 86.74  ? 430 GLN C OE1  1 
ATOM   4719  N  NE2  . GLN C 1 223 ? 77.630  -40.500 31.193  1.00 86.52  ? 430 GLN C NE2  1 
ATOM   4720  N  N    . LEU C 1 224 ? 72.874  -36.719 28.363  1.00 48.72  ? 431 LEU C N    1 
ATOM   4721  C  CA   . LEU C 1 224 ? 71.637  -36.472 27.631  1.00 53.52  ? 431 LEU C CA   1 
ATOM   4722  C  C    . LEU C 1 224 ? 71.546  -37.433 26.458  1.00 49.83  ? 431 LEU C C    1 
ATOM   4723  O  O    . LEU C 1 224 ? 72.155  -37.188 25.401  1.00 59.09  ? 431 LEU C O    1 
ATOM   4724  C  CB   . LEU C 1 224 ? 71.599  -35.019 27.161  1.00 52.55  ? 431 LEU C CB   1 
ATOM   4725  C  CG   . LEU C 1 224 ? 70.340  -34.557 26.450  1.00 55.90  ? 431 LEU C CG   1 
ATOM   4726  C  CD1  . LEU C 1 224 ? 69.100  -34.921 27.251  1.00 55.66  ? 431 LEU C CD1  1 
ATOM   4727  C  CD2  . LEU C 1 224 ? 70.421  -33.054 26.189  1.00 54.14  ? 431 LEU C CD2  1 
ATOM   4728  N  N    . PRO C 1 225 ? 70.830  -38.589 26.593  1.00 50.89  ? 432 PRO C N    1 
ATOM   4729  C  CA   . PRO C 1 225 ? 70.584  -39.467 25.449  1.00 56.46  ? 432 PRO C CA   1 
ATOM   4730  C  C    . PRO C 1 225 ? 69.471  -38.897 24.561  1.00 53.46  ? 432 PRO C C    1 
ATOM   4731  O  O    . PRO C 1 225 ? 68.377  -38.682 25.028  1.00 49.91  ? 432 PRO C O    1 
ATOM   4732  C  CB   . PRO C 1 225 ? 70.176  -40.819 26.050  1.00 53.34  ? 432 PRO C CB   1 
ATOM   4733  C  CG   . PRO C 1 225 ? 69.562  -40.490 27.374  1.00 50.48  ? 432 PRO C CG   1 
ATOM   4734  C  CD   . PRO C 1 225 ? 70.320  -39.266 27.825  1.00 48.14  ? 432 PRO C CD   1 
ATOM   4735  N  N    . LEU C 1 226 ? 69.782  -38.670 23.292  1.00 48.03  ? 433 LEU C N    1 
ATOM   4736  C  CA   . LEU C 1 226 ? 68.820  -38.025 22.403  1.00 53.97  ? 433 LEU C CA   1 
ATOM   4737  C  C    . LEU C 1 226 ? 68.381  -38.888 21.213  1.00 55.80  ? 433 LEU C C    1 
ATOM   4738  O  O    . LEU C 1 226 ? 67.670  -38.383 20.326  1.00 55.10  ? 433 LEU C O    1 
ATOM   4739  C  CB   . LEU C 1 226 ? 69.398  -36.685 21.915  1.00 54.31  ? 433 LEU C CB   1 
ATOM   4740  C  CG   . LEU C 1 226 ? 69.504  -35.589 23.002  1.00 54.69  ? 433 LEU C CG   1 
ATOM   4741  C  CD1  . LEU C 1 226 ? 70.060  -34.298 22.435  1.00 49.30  ? 433 LEU C CD1  1 
ATOM   4742  C  CD2  . LEU C 1 226 ? 68.147  -35.308 23.635  1.00 54.20  ? 433 LEU C CD2  1 
ATOM   4743  N  N    . ASP C 1 227 ? 68.753  -40.173 21.177  1.00 47.11  ? 434 ASP C N    1 
ATOM   4744  C  CA   . ASP C 1 227 ? 68.464  -41.018 20.012  1.00 57.66  ? 434 ASP C CA   1 
ATOM   4745  C  C    . ASP C 1 227 ? 66.963  -41.130 19.725  1.00 55.74  ? 434 ASP C C    1 
ATOM   4746  O  O    . ASP C 1 227 ? 66.565  -41.152 18.558  1.00 55.62  ? 434 ASP C O    1 
ATOM   4747  C  CB   . ASP C 1 227 ? 69.066  -42.425 20.197  1.00 60.34  ? 434 ASP C CB   1 
ATOM   4748  C  CG   . ASP C 1 227 ? 70.406  -42.621 19.450  1.00 54.16  ? 434 ASP C CG   1 
ATOM   4749  O  OD1  . ASP C 1 227 ? 70.922  -41.704 18.786  1.00 56.71  ? 434 ASP C OD1  1 
ATOM   4750  O  OD2  . ASP C 1 227 ? 70.951  -43.725 19.531  1.00 63.38  ? 434 ASP C OD2  1 
ATOM   4751  N  N    . GLU C 1 228 ? 66.115  -41.158 20.760  1.00 58.71  ? 435 GLU C N    1 
ATOM   4752  C  CA   . GLU C 1 228 ? 64.664  -41.215 20.568  1.00 56.58  ? 435 GLU C CA   1 
ATOM   4753  C  C    . GLU C 1 228 ? 64.087  -40.015 19.806  1.00 56.38  ? 435 GLU C C    1 
ATOM   4754  O  O    . GLU C 1 228 ? 62.900  -40.038 19.476  1.00 53.30  ? 435 GLU C O    1 
ATOM   4755  C  CB   . GLU C 1 228 ? 63.944  -41.306 21.926  1.00 57.16  ? 435 GLU C CB   1 
ATOM   4756  C  CG   . GLU C 1 228 ? 64.023  -42.654 22.605  1.00 59.35  ? 435 GLU C CG   1 
ATOM   4757  C  CD   . GLU C 1 228 ? 64.177  -43.805 21.618  1.00 72.78  ? 435 GLU C CD   1 
ATOM   4758  O  OE1  . GLU C 1 228 ? 63.172  -44.157 20.957  1.00 75.29  ? 435 GLU C OE1  1 
ATOM   4759  O  OE2  . GLU C 1 228 ? 65.306  -44.354 21.499  1.00 71.16  ? 435 GLU C OE2  1 
ATOM   4760  N  N    . PHE C 1 229 ? 64.860  -38.963 19.539  1.00 53.70  ? 436 PHE C N    1 
ATOM   4761  C  CA   . PHE C 1 229 ? 64.311  -37.773 18.900  1.00 52.23  ? 436 PHE C CA   1 
ATOM   4762  C  C    . PHE C 1 229 ? 64.859  -37.555 17.498  1.00 52.01  ? 436 PHE C C    1 
ATOM   4763  O  O    . PHE C 1 229 ? 64.534  -36.543 16.863  1.00 51.53  ? 436 PHE C O    1 
ATOM   4764  C  CB   . PHE C 1 229 ? 64.547  -36.548 19.790  1.00 42.75  ? 436 PHE C CB   1 
ATOM   4765  C  CG   . PHE C 1 229 ? 64.116  -36.774 21.210  1.00 53.65  ? 436 PHE C CG   1 
ATOM   4766  C  CD1  . PHE C 1 229 ? 62.753  -36.908 21.522  1.00 46.94  ? 436 PHE C CD1  1 
ATOM   4767  C  CD2  . PHE C 1 229 ? 65.059  -36.911 22.232  1.00 53.02  ? 436 PHE C CD2  1 
ATOM   4768  C  CE1  . PHE C 1 229 ? 62.334  -37.142 22.812  1.00 44.73  ? 436 PHE C CE1  1 
ATOM   4769  C  CE2  . PHE C 1 229 ? 64.648  -37.146 23.548  1.00 50.38  ? 436 PHE C CE2  1 
ATOM   4770  C  CZ   . PHE C 1 229 ? 63.274  -37.253 23.838  1.00 52.27  ? 436 PHE C CZ   1 
ATOM   4771  N  N    . LEU C 1 230 ? 65.658  -38.479 16.983  1.00 54.56  ? 437 LEU C N    1 
ATOM   4772  C  CA   . LEU C 1 230 ? 66.067  -38.342 15.593  1.00 52.86  ? 437 LEU C CA   1 
ATOM   4773  C  C    . LEU C 1 230 ? 65.113  -39.121 14.690  1.00 55.22  ? 437 LEU C C    1 
ATOM   4774  O  O    . LEU C 1 230 ? 64.367  -39.996 15.138  1.00 61.59  ? 437 LEU C O    1 
ATOM   4775  C  CB   . LEU C 1 230 ? 67.498  -38.822 15.396  1.00 49.94  ? 437 LEU C CB   1 
ATOM   4776  C  CG   . LEU C 1 230 ? 68.619  -38.041 16.077  1.00 45.81  ? 437 LEU C CG   1 
ATOM   4777  C  CD1  . LEU C 1 230 ? 69.760  -39.011 16.418  1.00 53.60  ? 437 LEU C CD1  1 
ATOM   4778  C  CD2  . LEU C 1 230 ? 69.114  -36.933 15.186  1.00 46.34  ? 437 LEU C CD2  1 
ATOM   4779  N  N    . GLN C 1 231 ? 65.107  -38.750 13.411  1.00 58.17  ? 438 GLN C N    1 
ATOM   4780  C  CA   . GLN C 1 231 ? 64.370  -39.524 12.422  1.00 54.87  ? 438 GLN C CA   1 
ATOM   4781  C  C    . GLN C 1 231 ? 65.028  -40.881 12.182  1.00 59.89  ? 438 GLN C C    1 
ATOM   4782  O  O    . GLN C 1 231 ? 64.333  -41.871 11.931  1.00 63.23  ? 438 GLN C O    1 
ATOM   4783  C  CB   . GLN C 1 231 ? 64.261  -38.720 11.131  1.00 52.39  ? 438 GLN C CB   1 
ATOM   4784  C  CG   . GLN C 1 231 ? 63.078  -39.082 10.234  1.00 60.56  ? 438 GLN C CG   1 
ATOM   4785  C  CD   . GLN C 1 231 ? 61.759  -39.258 11.000  1.00 65.01  ? 438 GLN C CD   1 
ATOM   4786  O  OE1  . GLN C 1 231 ? 61.225  -38.310 11.578  1.00 69.47  ? 438 GLN C OE1  1 
ATOM   4787  N  NE2  . GLN C 1 231 ? 61.234  -40.478 10.999  1.00 64.19  ? 438 GLN C NE2  1 
ATOM   4788  N  N    . LYS C 1 232 ? 66.353  -40.958 12.284  1.00 58.80  ? 439 LYS C N    1 
ATOM   4789  C  CA   . LYS C 1 232 ? 67.069  -42.220 12.119  1.00 57.17  ? 439 LYS C CA   1 
ATOM   4790  C  C    . LYS C 1 232 ? 68.294  -42.241 13.026  1.00 61.32  ? 439 LYS C C    1 
ATOM   4791  O  O    . LYS C 1 232 ? 69.107  -41.314 12.992  1.00 57.60  ? 439 LYS C O    1 
ATOM   4792  C  CB   . LYS C 1 232 ? 67.499  -42.425 10.667  1.00 60.16  ? 439 LYS C CB   1 
ATOM   4793  C  CG   . LYS C 1 232 ? 68.270  -43.699 10.440  1.00 59.84  ? 439 LYS C CG   1 
ATOM   4794  C  CD   . LYS C 1 232 ? 68.734  -43.816 9.001   1.00 58.60  ? 439 LYS C CD   1 
ATOM   4795  C  CE   . LYS C 1 232 ? 69.547  -45.092 8.825   1.00 64.53  ? 439 LYS C CE   1 
ATOM   4796  N  NZ   . LYS C 1 232 ? 69.132  -46.077 9.869   1.00 63.50  ? 439 LYS C NZ   1 
ATOM   4797  N  N    . THR C 1 233 ? 68.424  -43.287 13.837  1.00 60.44  ? 440 THR C N    1 
ATOM   4798  C  CA   . THR C 1 233 ? 69.596  -43.407 14.689  1.00 56.03  ? 440 THR C CA   1 
ATOM   4799  C  C    . THR C 1 233 ? 70.732  -44.072 13.921  1.00 61.22  ? 440 THR C C    1 
ATOM   4800  O  O    . THR C 1 233 ? 70.536  -44.660 12.853  1.00 63.64  ? 440 THR C O    1 
ATOM   4801  C  CB   . THR C 1 233 ? 69.271  -44.196 15.957  1.00 55.96  ? 440 THR C CB   1 
ATOM   4802  O  OG1  . THR C 1 233 ? 69.134  -45.580 15.634  1.00 56.62  ? 440 THR C OG1  1 
ATOM   4803  C  CG2  . THR C 1 233 ? 67.969  -43.705 16.573  1.00 52.74  ? 440 THR C CG2  1 
ATOM   4804  N  N    . ASP C 1 234 ? 71.938  -43.954 14.471  1.00 66.97  ? 441 ASP C N    1 
ATOM   4805  C  CA   . ASP C 1 234 ? 73.149  -44.522 13.879  1.00 60.69  ? 441 ASP C CA   1 
ATOM   4806  C  C    . ASP C 1 234 ? 73.830  -45.373 14.944  1.00 64.43  ? 441 ASP C C    1 
ATOM   4807  O  O    . ASP C 1 234 ? 74.477  -44.826 15.851  1.00 68.47  ? 441 ASP C O    1 
ATOM   4808  C  CB   . ASP C 1 234 ? 74.059  -43.409 13.380  1.00 62.82  ? 441 ASP C CB   1 
ATOM   4809  C  CG   . ASP C 1 234 ? 75.384  -43.914 12.816  1.00 70.03  ? 441 ASP C CG   1 
ATOM   4810  O  OD1  . ASP C 1 234 ? 75.662  -45.144 12.854  1.00 64.19  ? 441 ASP C OD1  1 
ATOM   4811  O  OD2  . ASP C 1 234 ? 76.151  -43.045 12.327  1.00 64.37  ? 441 ASP C OD2  1 
ATOM   4812  N  N    . PRO C 1 235 ? 73.729  -46.702 14.864  1.00 69.98  ? 442 PRO C N    1 
ATOM   4813  C  CA   . PRO C 1 235 ? 74.271  -47.547 15.948  1.00 69.37  ? 442 PRO C CA   1 
ATOM   4814  C  C    . PRO C 1 235 ? 75.765  -47.386 16.159  1.00 69.14  ? 442 PRO C C    1 
ATOM   4815  O  O    . PRO C 1 235 ? 76.276  -47.747 17.226  1.00 74.29  ? 442 PRO C O    1 
ATOM   4816  C  CB   . PRO C 1 235 ? 73.920  -48.972 15.495  1.00 71.03  ? 442 PRO C CB   1 
ATOM   4817  C  CG   . PRO C 1 235 ? 72.804  -48.801 14.486  1.00 70.23  ? 442 PRO C CG   1 
ATOM   4818  C  CD   . PRO C 1 235 ? 73.118  -47.503 13.789  1.00 70.17  ? 442 PRO C CD   1 
ATOM   4819  N  N    . LYS C 1 236 ? 76.464  -46.798 15.201  1.00 71.70  ? 443 LYS C N    1 
ATOM   4820  C  CA   . LYS C 1 236 ? 77.914  -46.551 15.390  1.00 72.01  ? 443 LYS C CA   1 
ATOM   4821  C  C    . LYS C 1 236 ? 78.148  -45.222 16.117  1.00 72.71  ? 443 LYS C C    1 
ATOM   4822  O  O    . LYS C 1 236 ? 79.287  -45.004 16.555  1.00 76.93  ? 443 LYS C O    1 
ATOM   4823  C  CB   . LYS C 1 236 ? 78.623  -46.568 14.033  1.00 63.02  ? 443 LYS C CB   1 
ATOM   4824  N  N    . ASP C 1 237 ? 77.123  -44.383 16.261  1.00 71.47  ? 444 ASP C N    1 
ATOM   4825  C  CA   . ASP C 1 237 ? 77.302  -43.058 16.862  1.00 66.24  ? 444 ASP C CA   1 
ATOM   4826  C  C    . ASP C 1 237 ? 75.998  -42.587 17.485  1.00 62.87  ? 444 ASP C C    1 
ATOM   4827  O  O    . ASP C 1 237 ? 75.369  -41.638 17.007  1.00 58.78  ? 444 ASP C O    1 
ATOM   4828  C  CB   . ASP C 1 237 ? 77.782  -42.049 15.827  1.00 60.67  ? 444 ASP C CB   1 
ATOM   4829  C  CG   . ASP C 1 237 ? 78.019  -40.689 16.437  1.00 66.65  ? 444 ASP C CG   1 
ATOM   4830  O  OD1  . ASP C 1 237 ? 78.083  -40.627 17.692  1.00 58.67  ? 444 ASP C OD1  1 
ATOM   4831  O  OD2  . ASP C 1 237 ? 78.144  -39.696 15.674  1.00 66.52  ? 444 ASP C OD2  1 
ATOM   4832  N  N    . PRO C 1 238 ? 75.594  -43.193 18.597  1.00 63.75  ? 445 PRO C N    1 
ATOM   4833  C  CA   . PRO C 1 238 ? 74.335  -42.790 19.237  1.00 61.95  ? 445 PRO C CA   1 
ATOM   4834  C  C    . PRO C 1 238 ? 74.418  -41.358 19.719  1.00 61.76  ? 445 PRO C C    1 
ATOM   4835  O  O    . PRO C 1 238 ? 75.498  -40.851 20.033  1.00 65.34  ? 445 PRO C O    1 
ATOM   4836  C  CB   . PRO C 1 238 ? 74.209  -43.759 20.410  1.00 61.39  ? 445 PRO C CB   1 
ATOM   4837  C  CG   . PRO C 1 238 ? 75.640  -44.017 20.788  1.00 68.62  ? 445 PRO C CG   1 
ATOM   4838  C  CD   . PRO C 1 238 ? 76.440  -43.995 19.497  1.00 64.31  ? 445 PRO C CD   1 
ATOM   4839  N  N    . ALA C 1 239 ? 73.259  -40.699 19.772  1.00 60.25  ? 446 ALA C N    1 
ATOM   4840  C  CA   . ALA C 1 239 ? 73.199  -39.283 20.140  1.00 55.84  ? 446 ALA C CA   1 
ATOM   4841  C  C    . ALA C 1 239 ? 73.226  -39.096 21.664  1.00 55.16  ? 446 ALA C C    1 
ATOM   4842  O  O    . ALA C 1 239 ? 72.289  -38.585 22.279  1.00 56.82  ? 446 ALA C O    1 
ATOM   4843  C  CB   . ALA C 1 239 ? 71.965  -38.648 19.518  1.00 51.50  ? 446 ALA C CB   1 
ATOM   4844  N  N    . ASN C 1 240 ? 74.339  -39.522 22.273  1.00 61.27  ? 447 ASN C N    1 
ATOM   4845  C  CA   . ASN C 1 240 ? 74.584  -39.354 23.709  1.00 58.43  ? 447 ASN C CA   1 
ATOM   4846  C  C    . ASN C 1 240 ? 75.391  -38.076 23.926  1.00 58.83  ? 447 ASN C C    1 
ATOM   4847  O  O    . ASN C 1 240 ? 76.487  -37.931 23.369  1.00 56.26  ? 447 ASN C O    1 
ATOM   4848  C  CB   . ASN C 1 240 ? 75.344  -40.551 24.273  1.00 58.28  ? 447 ASN C CB   1 
ATOM   4849  C  CG   . ASN C 1 240 ? 74.498  -41.810 24.327  1.00 63.05  ? 447 ASN C CG   1 
ATOM   4850  O  OD1  . ASN C 1 240 ? 73.388  -41.793 24.834  1.00 67.41  ? 447 ASN C OD1  1 
ATOM   4851  N  ND2  . ASN C 1 240 ? 75.028  -42.907 23.812  1.00 64.00  ? 447 ASN C ND2  1 
ATOM   4852  N  N    . TYR C 1 241 ? 74.845  -37.190 24.754  1.00 53.33  ? 448 TYR C N    1 
ATOM   4853  C  CA   . TYR C 1 241 ? 75.472  -35.860 24.917  1.00 56.00  ? 448 TYR C CA   1 
ATOM   4854  C  C    . TYR C 1 241 ? 75.971  -35.644 26.336  1.00 54.34  ? 448 TYR C C    1 
ATOM   4855  O  O    . TYR C 1 241 ? 75.282  -35.979 27.288  1.00 58.28  ? 448 TYR C O    1 
ATOM   4856  C  CB   . TYR C 1 241 ? 74.494  -34.769 24.480  1.00 53.28  ? 448 TYR C CB   1 
ATOM   4857  C  CG   . TYR C 1 241 ? 74.470  -34.593 22.989  1.00 56.76  ? 448 TYR C CG   1 
ATOM   4858  C  CD1  . TYR C 1 241 ? 73.797  -35.490 22.181  1.00 51.38  ? 448 TYR C CD1  1 
ATOM   4859  C  CD2  . TYR C 1 241 ? 75.163  -33.561 22.388  1.00 51.41  ? 448 TYR C CD2  1 
ATOM   4860  C  CE1  . TYR C 1 241 ? 73.799  -35.363 20.807  1.00 49.51  ? 448 TYR C CE1  1 
ATOM   4861  C  CE2  . TYR C 1 241 ? 75.173  -33.413 21.015  1.00 45.57  ? 448 TYR C CE2  1 
ATOM   4862  C  CZ   . TYR C 1 241 ? 74.488  -34.317 20.228  1.00 50.99  ? 448 TYR C CZ   1 
ATOM   4863  O  OH   . TYR C 1 241 ? 74.510  -34.201 18.879  1.00 50.17  ? 448 TYR C OH   1 
ATOM   4864  N  N    . ILE C 1 242 ? 77.151  -35.035 26.469  1.00 57.34  ? 449 ILE C N    1 
ATOM   4865  C  CA   . ILE C 1 242 ? 77.753  -34.740 27.803  1.00 58.92  ? 449 ILE C CA   1 
ATOM   4866  C  C    . ILE C 1 242 ? 77.620  -33.248 28.097  1.00 55.72  ? 449 ILE C C    1 
ATOM   4867  O  O    . ILE C 1 242 ? 78.014  -32.457 27.237  1.00 56.69  ? 449 ILE C O    1 
ATOM   4868  C  CB   . ILE C 1 242 ? 79.232  -35.165 27.841  1.00 54.71  ? 449 ILE C CB   1 
ATOM   4869  C  CG1  . ILE C 1 242 ? 79.447  -36.555 27.236  1.00 64.37  ? 449 ILE C CG1  1 
ATOM   4870  C  CG2  . ILE C 1 242 ? 79.791  -35.073 29.251  1.00 51.91  ? 449 ILE C CG2  1 
ATOM   4871  C  CD1  . ILE C 1 242 ? 79.065  -37.690 28.152  1.00 67.89  ? 449 ILE C CD1  1 
ATOM   4872  N  N    . LEU C 1 243 ? 77.115  -32.891 29.281  1.00 50.41  ? 450 LEU C N    1 
ATOM   4873  C  CA   . LEU C 1 243 ? 76.979  -31.470 29.691  1.00 51.10  ? 450 LEU C CA   1 
ATOM   4874  C  C    . LEU C 1 243 ? 78.353  -30.805 29.774  1.00 53.80  ? 450 LEU C C    1 
ATOM   4875  O  O    . LEU C 1 243 ? 79.252  -31.384 30.391  1.00 50.55  ? 450 LEU C O    1 
ATOM   4876  C  CB   . LEU C 1 243 ? 76.252  -31.416 31.035  1.00 49.28  ? 450 LEU C CB   1 
ATOM   4877  C  CG   . LEU C 1 243 ? 75.867  -30.035 31.560  1.00 49.64  ? 450 LEU C CG   1 
ATOM   4878  C  CD1  . LEU C 1 243 ? 75.130  -29.227 30.509  1.00 57.21  ? 450 LEU C CD1  1 
ATOM   4879  C  CD2  . LEU C 1 243 ? 75.016  -30.170 32.807  1.00 48.89  ? 450 LEU C CD2  1 
ATOM   4880  N  N    . HIS C 1 244 ? 78.483  -29.622 29.183  1.00 51.62  ? 451 HIS C N    1 
ATOM   4881  C  CA   . HIS C 1 244 ? 79.758  -28.870 29.181  1.00 51.12  ? 451 HIS C CA   1 
ATOM   4882  C  C    . HIS C 1 244 ? 79.551  -27.540 29.896  1.00 57.54  ? 451 HIS C C    1 
ATOM   4883  O  O    . HIS C 1 244 ? 80.412  -27.199 30.704  1.00 65.03  ? 451 HIS C O    1 
ATOM   4884  C  CB   . HIS C 1 244 ? 80.227  -28.664 27.741  1.00 54.57  ? 451 HIS C CB   1 
ATOM   4885  C  CG   . HIS C 1 244 ? 81.569  -28.041 27.577  1.00 52.65  ? 451 HIS C CG   1 
ATOM   4886  N  ND1  . HIS C 1 244 ? 81.770  -26.955 26.756  1.00 52.02  ? 451 HIS C ND1  1 
ATOM   4887  C  CD2  . HIS C 1 244 ? 82.778  -28.373 28.071  1.00 55.86  ? 451 HIS C CD2  1 
ATOM   4888  C  CE1  . HIS C 1 244 ? 83.042  -26.629 26.769  1.00 50.02  ? 451 HIS C CE1  1 
ATOM   4889  N  NE2  . HIS C 1 244 ? 83.680  -27.480 27.569  1.00 53.58  ? 451 HIS C NE2  1 
ATOM   4890  N  N    . ALA C 1 245 ? 78.459  -26.824 29.607  1.00 55.85  ? 452 ALA C N    1 
ATOM   4891  C  CA   . ALA C 1 245 ? 78.299  -25.501 30.206  1.00 57.22  ? 452 ALA C CA   1 
ATOM   4892  C  C    . ALA C 1 245 ? 76.842  -25.257 30.580  1.00 55.09  ? 452 ALA C C    1 
ATOM   4893  O  O    . ALA C 1 245 ? 75.923  -25.748 29.922  1.00 57.85  ? 452 ALA C O    1 
ATOM   4894  C  CB   . ALA C 1 245 ? 78.786  -24.376 29.274  1.00 49.95  ? 452 ALA C CB   1 
ATOM   4895  N  N    . VAL C 1 246 ? 76.655  -24.513 31.673  1.00 54.68  ? 453 VAL C N    1 
ATOM   4896  C  CA   . VAL C 1 246 ? 75.300  -24.143 32.162  1.00 53.89  ? 453 VAL C CA   1 
ATOM   4897  C  C    . VAL C 1 246 ? 75.315  -22.625 32.316  1.00 56.81  ? 453 VAL C C    1 
ATOM   4898  O  O    . VAL C 1 246 ? 75.860  -22.145 33.313  1.00 58.38  ? 453 VAL C O    1 
ATOM   4899  C  CB   . VAL C 1 246 ? 74.972  -24.836 33.497  1.00 53.45  ? 453 VAL C CB   1 
ATOM   4900  C  CG1  . VAL C 1 246 ? 73.584  -24.493 33.994  1.00 49.66  ? 453 VAL C CG1  1 
ATOM   4901  C  CG2  . VAL C 1 246 ? 75.167  -26.340 33.449  1.00 45.62  ? 453 VAL C CG2  1 
ATOM   4902  N  N    . LEU C 1 247 ? 74.795  -21.905 31.327  1.00 56.12  ? 454 LEU C N    1 
ATOM   4903  C  CA   . LEU C 1 247 ? 74.781  -20.421 31.364  1.00 53.80  ? 454 LEU C CA   1 
ATOM   4904  C  C    . LEU C 1 247 ? 73.626  -19.990 32.261  1.00 52.20  ? 454 LEU C C    1 
ATOM   4905  O  O    . LEU C 1 247 ? 72.478  -20.189 31.875  1.00 53.81  ? 454 LEU C O    1 
ATOM   4906  C  CB   . LEU C 1 247 ? 74.713  -19.873 29.939  1.00 50.12  ? 454 LEU C CB   1 
ATOM   4907  C  CG   . LEU C 1 247 ? 76.007  -20.012 29.141  1.00 59.19  ? 454 LEU C CG   1 
ATOM   4908  C  CD1  . LEU C 1 247 ? 76.001  -21.266 28.282  1.00 51.63  ? 454 LEU C CD1  1 
ATOM   4909  C  CD2  . LEU C 1 247 ? 76.258  -18.785 28.288  1.00 54.14  ? 454 LEU C CD2  1 
ATOM   4910  N  N    . VAL C 1 248 ? 73.948  -19.398 33.406  1.00 57.45  ? 455 VAL C N    1 
ATOM   4911  C  CA   . VAL C 1 248 ? 72.929  -19.101 34.444  1.00 52.74  ? 455 VAL C CA   1 
ATOM   4912  C  C    . VAL C 1 248 ? 72.551  -17.632 34.487  1.00 56.47  ? 455 VAL C C    1 
ATOM   4913  O  O    . VAL C 1 248 ? 73.438  -16.781 34.420  1.00 60.22  ? 455 VAL C O    1 
ATOM   4914  C  CB   . VAL C 1 248 ? 73.464  -19.574 35.801  1.00 55.56  ? 455 VAL C CB   1 
ATOM   4915  C  CG1  . VAL C 1 248 ? 72.523  -19.265 36.948  1.00 60.63  ? 455 VAL C CG1  1 
ATOM   4916  C  CG2  . VAL C 1 248 ? 73.777  -21.052 35.748  1.00 60.38  ? 455 VAL C CG2  1 
ATOM   4917  N  N    . HIS C 1 249 ? 71.264  -17.382 34.632  1.00 55.87  ? 456 HIS C N    1 
ATOM   4918  C  CA   . HIS C 1 249 ? 70.718  -16.037 34.718  1.00 61.05  ? 456 HIS C CA   1 
ATOM   4919  C  C    . HIS C 1 249 ? 70.063  -15.826 36.085  1.00 58.42  ? 456 HIS C C    1 
ATOM   4920  O  O    . HIS C 1 249 ? 69.458  -16.745 36.648  1.00 62.35  ? 456 HIS C O    1 
ATOM   4921  C  CB   . HIS C 1 249 ? 69.702  -15.783 33.595  1.00 58.44  ? 456 HIS C CB   1 
ATOM   4922  C  CG   . HIS C 1 249 ? 69.038  -14.446 33.684  1.00 60.51  ? 456 HIS C CG   1 
ATOM   4923  N  ND1  . HIS C 1 249 ? 67.844  -14.252 34.346  1.00 57.12  ? 456 HIS C ND1  1 
ATOM   4924  C  CD2  . HIS C 1 249 ? 69.419  -13.230 33.222  1.00 56.81  ? 456 HIS C CD2  1 
ATOM   4925  C  CE1  . HIS C 1 249 ? 67.514  -12.975 34.276  1.00 62.94  ? 456 HIS C CE1  1 
ATOM   4926  N  NE2  . HIS C 1 249 ? 68.453  -12.334 33.600  1.00 60.53  ? 456 HIS C NE2  1 
ATOM   4927  N  N    . SER C 1 250 ? 70.242  -14.629 36.636  1.00 63.46  ? 457 SER C N    1 
ATOM   4928  C  CA   . SER C 1 250 ? 69.636  -14.292 37.944  1.00 64.70  ? 457 SER C CA   1 
ATOM   4929  C  C    . SER C 1 250 ? 68.920  -12.955 37.816  1.00 62.47  ? 457 SER C C    1 
ATOM   4930  O  O    . SER C 1 250 ? 69.541  -12.032 37.324  1.00 62.73  ? 457 SER C O    1 
ATOM   4931  C  CB   . SER C 1 250 ? 70.671  -14.232 39.029  1.00 64.32  ? 457 SER C CB   1 
ATOM   4932  O  OG   . SER C 1 250 ? 71.642  -15.256 38.891  1.00 67.89  ? 457 SER C OG   1 
ATOM   4933  N  N    . GLY C 1 251 ? 67.654  -12.885 38.215  1.00 64.00  ? 458 GLY C N    1 
ATOM   4934  C  CA   . GLY C 1 251 ? 66.936  -11.599 38.221  1.00 71.61  ? 458 GLY C CA   1 
ATOM   4935  C  C    . GLY C 1 251 ? 65.582  -11.653 37.548  1.00 79.80  ? 458 GLY C C    1 
ATOM   4936  O  O    . GLY C 1 251 ? 64.880  -12.665 37.717  1.00 77.56  ? 458 GLY C O    1 
ATOM   4937  N  N    . ASP C 1 252 ? 65.216  -10.580 36.844  1.00 80.06  ? 459 ASP C N    1 
ATOM   4938  C  CA   . ASP C 1 252 ? 63.927  -10.519 36.106  1.00 80.65  ? 459 ASP C CA   1 
ATOM   4939  C  C    . ASP C 1 252 ? 64.196  -10.436 34.603  1.00 78.49  ? 459 ASP C C    1 
ATOM   4940  O  O    . ASP C 1 252 ? 65.353  -10.589 34.190  1.00 77.18  ? 459 ASP C O    1 
ATOM   4941  C  CB   . ASP C 1 252 ? 63.087  -9.322  36.550  1.00 81.51  ? 459 ASP C CB   1 
ATOM   4942  C  CG   . ASP C 1 252 ? 63.873  -8.029  36.653  1.00 82.44  ? 459 ASP C CG   1 
ATOM   4943  O  OD1  . ASP C 1 252 ? 64.006  -7.348  35.627  1.00 74.27  ? 459 ASP C OD1  1 
ATOM   4944  O  OD2  . ASP C 1 252 ? 64.343  -7.719  37.763  1.00 91.32  ? 459 ASP C OD2  1 
ATOM   4945  N  N    . ASN C 1 253 ? 63.159  -10.160 33.817  1.00 81.10  ? 460 ASN C N    1 
ATOM   4946  C  CA   . ASN C 1 253 ? 63.316  -10.120 32.341  1.00 81.25  ? 460 ASN C CA   1 
ATOM   4947  C  C    . ASN C 1 253 ? 64.053  -8.845  31.944  1.00 81.92  ? 460 ASN C C    1 
ATOM   4948  O  O    . ASN C 1 253 ? 64.844  -8.909  30.983  1.00 74.89  ? 460 ASN C O    1 
ATOM   4949  C  CB   . ASN C 1 253 ? 61.967  -10.244 31.631  1.00 76.69  ? 460 ASN C CB   1 
ATOM   4950  N  N    . HIS C 1 254 ? 63.828  -7.749  32.673  1.00 77.63  ? 461 HIS C N    1 
ATOM   4951  C  CA   . HIS C 1 254 ? 64.423  -6.442  32.288  1.00 79.65  ? 461 HIS C CA   1 
ATOM   4952  C  C    . HIS C 1 254 ? 65.883  -6.325  32.732  1.00 76.30  ? 461 HIS C C    1 
ATOM   4953  O  O    . HIS C 1 254 ? 66.554  -5.399  32.250  1.00 81.29  ? 461 HIS C O    1 
ATOM   4954  C  CB   . HIS C 1 254 ? 63.579  -5.297  32.853  1.00 84.31  ? 461 HIS C CB   1 
ATOM   4955  N  N    . GLY C 1 255 ? 66.352  -7.198  33.622  1.00 75.88  ? 462 GLY C N    1 
ATOM   4956  C  CA   . GLY C 1 255 ? 67.729  -7.038  34.117  1.00 73.61  ? 462 GLY C CA   1 
ATOM   4957  C  C    . GLY C 1 255 ? 68.157  -8.105  35.101  1.00 76.63  ? 462 GLY C C    1 
ATOM   4958  O  O    . GLY C 1 255 ? 67.284  -8.745  35.709  1.00 72.18  ? 462 GLY C O    1 
ATOM   4959  N  N    . GLY C 1 256 ? 69.470  -8.276  35.250  1.00 66.45  ? 463 GLY C N    1 
ATOM   4960  C  CA   . GLY C 1 256 ? 69.990  -9.243  36.226  1.00 61.15  ? 463 GLY C CA   1 
ATOM   4961  C  C    . GLY C 1 256 ? 71.460  -9.544  36.036  1.00 60.34  ? 463 GLY C C    1 
ATOM   4962  O  O    . GLY C 1 256 ? 72.199  -8.657  35.594  1.00 62.18  ? 463 GLY C O    1 
ATOM   4963  N  N    . HIS C 1 257 ? 71.868  -10.756 36.396  1.00 61.26  ? 464 HIS C N    1 
ATOM   4964  C  CA   . HIS C 1 257 ? 73.299  -11.123 36.293  1.00 62.60  ? 464 HIS C CA   1 
ATOM   4965  C  C    . HIS C 1 257 ? 73.477  -12.436 35.543  1.00 63.52  ? 464 HIS C C    1 
ATOM   4966  O  O    . HIS C 1 257 ? 72.590  -13.293 35.609  1.00 62.49  ? 464 HIS C O    1 
ATOM   4967  C  CB   . HIS C 1 257 ? 73.972  -11.184 37.663  1.00 54.74  ? 464 HIS C CB   1 
ATOM   4968  C  CG   . HIS C 1 257 ? 75.450  -11.032 37.569  1.00 56.47  ? 464 HIS C CG   1 
ATOM   4969  N  ND1  . HIS C 1 257 ? 76.034  -9.903  37.045  1.00 54.14  ? 464 HIS C ND1  1 
ATOM   4970  C  CD2  . HIS C 1 257 ? 76.455  -11.872 37.882  1.00 59.01  ? 464 HIS C CD2  1 
ATOM   4971  C  CE1  . HIS C 1 257 ? 77.340  -10.041 37.063  1.00 56.31  ? 464 HIS C CE1  1 
ATOM   4972  N  NE2  . HIS C 1 257 ? 77.622  -11.238 37.570  1.00 60.36  ? 464 HIS C NE2  1 
ATOM   4973  N  N    . TYR C 1 258 ? 74.613  -12.572 34.880  1.00 59.35  ? 465 TYR C N    1 
ATOM   4974  C  CA   . TYR C 1 258 ? 74.923  -13.783 34.093  1.00 57.51  ? 465 TYR C CA   1 
ATOM   4975  C  C    . TYR C 1 258 ? 76.260  -14.413 34.451  1.00 59.92  ? 465 TYR C C    1 
ATOM   4976  O  O    . TYR C 1 258 ? 77.283  -13.719 34.384  1.00 63.39  ? 465 TYR C O    1 
ATOM   4977  C  CB   . TYR C 1 258 ? 75.043  -13.424 32.617  1.00 59.44  ? 465 TYR C CB   1 
ATOM   4978  C  CG   . TYR C 1 258 ? 73.816  -13.624 31.774  1.00 60.66  ? 465 TYR C CG   1 
ATOM   4979  C  CD1  . TYR C 1 258 ? 73.212  -14.862 31.668  1.00 56.95  ? 465 TYR C CD1  1 
ATOM   4980  C  CD2  . TYR C 1 258 ? 73.288  -12.572 31.052  1.00 58.35  ? 465 TYR C CD2  1 
ATOM   4981  C  CE1  . TYR C 1 258 ? 72.092  -15.046 30.878  1.00 56.30  ? 465 TYR C CE1  1 
ATOM   4982  C  CE2  . TYR C 1 258 ? 72.174  -12.739 30.254  1.00 60.10  ? 465 TYR C CE2  1 
ATOM   4983  C  CZ   . TYR C 1 258 ? 71.575  -13.979 30.170  1.00 58.35  ? 465 TYR C CZ   1 
ATOM   4984  O  OH   . TYR C 1 258 ? 70.482  -14.136 29.379  1.00 57.01  ? 465 TYR C OH   1 
ATOM   4985  N  N    . VAL C 1 259 ? 76.242  -15.676 34.848  1.00 53.41  ? 466 VAL C N    1 
ATOM   4986  C  CA   . VAL C 1 259 ? 77.433  -16.482 35.059  1.00 54.88  ? 466 VAL C CA   1 
ATOM   4987  C  C    . VAL C 1 259 ? 77.291  -17.748 34.215  1.00 62.14  ? 466 VAL C C    1 
ATOM   4988  O  O    . VAL C 1 259 ? 76.205  -18.059 33.709  1.00 58.18  ? 466 VAL C O    1 
ATOM   4989  C  CB   . VAL C 1 259 ? 77.622  -16.843 36.544  1.00 59.43  ? 466 VAL C CB   1 
ATOM   4990  C  CG1  . VAL C 1 259 ? 77.377  -15.638 37.412  1.00 57.40  ? 466 VAL C CG1  1 
ATOM   4991  C  CG2  . VAL C 1 259 ? 76.682  -17.990 36.945  1.00 55.19  ? 466 VAL C CG2  1 
ATOM   4992  N  N    . VAL C 1 260 ? 78.408  -18.480 34.128  1.00 54.45  ? 467 VAL C N    1 
ATOM   4993  C  CA   . VAL C 1 260 ? 78.406  -19.789 33.424  1.00 58.55  ? 467 VAL C CA   1 
ATOM   4994  C  C    . VAL C 1 260 ? 79.177  -20.822 34.255  1.00 62.04  ? 467 VAL C C    1 
ATOM   4995  O  O    . VAL C 1 260 ? 80.256  -20.493 34.762  1.00 59.07  ? 467 VAL C O    1 
ATOM   4996  C  CB   . VAL C 1 260 ? 78.991  -19.667 32.006  1.00 56.88  ? 467 VAL C CB   1 
ATOM   4997  C  CG1  . VAL C 1 260 ? 80.373  -19.036 31.977  1.00 56.50  ? 467 VAL C CG1  1 
ATOM   4998  C  CG2  . VAL C 1 260 ? 78.985  -20.996 31.273  1.00 54.47  ? 467 VAL C CG2  1 
ATOM   4999  N  N    . TYR C 1 261 ? 78.606  -22.010 34.460  1.00 59.94  ? 468 TYR C N    1 
ATOM   5000  C  CA   . TYR C 1 261 ? 79.364  -23.102 35.100  1.00 60.89  ? 468 TYR C CA   1 
ATOM   5001  C  C    . TYR C 1 261 ? 79.910  -23.964 33.964  1.00 60.81  ? 468 TYR C C    1 
ATOM   5002  O  O    . TYR C 1 261 ? 79.123  -24.337 33.099  1.00 62.51  ? 468 TYR C O    1 
ATOM   5003  C  CB   . TYR C 1 261 ? 78.442  -23.870 36.040  1.00 58.55  ? 468 TYR C CB   1 
ATOM   5004  C  CG   . TYR C 1 261 ? 77.966  -23.099 37.243  1.00 63.99  ? 468 TYR C CG   1 
ATOM   5005  C  CD1  . TYR C 1 261 ? 76.957  -22.158 37.138  1.00 60.13  ? 468 TYR C CD1  1 
ATOM   5006  C  CD2  . TYR C 1 261 ? 78.512  -23.320 38.493  1.00 61.94  ? 468 TYR C CD2  1 
ATOM   5007  C  CE1  . TYR C 1 261 ? 76.513  -21.450 38.239  1.00 63.79  ? 468 TYR C CE1  1 
ATOM   5008  C  CE2  . TYR C 1 261 ? 78.071  -22.632 39.609  1.00 59.93  ? 468 TYR C CE2  1 
ATOM   5009  C  CZ   . TYR C 1 261 ? 77.070  -21.687 39.480  1.00 65.54  ? 468 TYR C CZ   1 
ATOM   5010  O  OH   . TYR C 1 261 ? 76.628  -20.991 40.564  1.00 69.92  ? 468 TYR C OH   1 
ATOM   5011  N  N    . LEU C 1 262 ? 81.208  -24.257 33.963  1.00 60.98  ? 469 LEU C N    1 
ATOM   5012  C  CA   . LEU C 1 262 ? 81.815  -24.994 32.834  1.00 53.99  ? 469 LEU C CA   1 
ATOM   5013  C  C    . LEU C 1 262 ? 82.742  -26.105 33.319  1.00 59.79  ? 469 LEU C C    1 
ATOM   5014  O  O    . LEU C 1 262 ? 83.439  -25.875 34.310  1.00 64.46  ? 469 LEU C O    1 
ATOM   5015  C  CB   . LEU C 1 262 ? 82.641  -23.994 32.027  1.00 59.14  ? 469 LEU C CB   1 
ATOM   5016  C  CG   . LEU C 1 262 ? 82.082  -23.528 30.691  1.00 57.31  ? 469 LEU C CG   1 
ATOM   5017  C  CD1  . LEU C 1 262 ? 82.517  -22.099 30.425  1.00 56.85  ? 469 LEU C CD1  1 
ATOM   5018  C  CD2  . LEU C 1 262 ? 82.564  -24.433 29.574  1.00 52.51  ? 469 LEU C CD2  1 
ATOM   5019  N  N    . ASN C 1 263 ? 82.698  -27.283 32.690  1.00 62.78  ? 470 ASN C N    1 
ATOM   5020  C  CA   . ASN C 1 263 ? 83.707  -28.348 32.951  1.00 62.36  ? 470 ASN C CA   1 
ATOM   5021  C  C    . ASN C 1 263 ? 84.556  -28.356 31.683  1.00 64.60  ? 470 ASN C C    1 
ATOM   5022  O  O    . ASN C 1 263 ? 84.333  -29.210 30.821  1.00 62.65  ? 470 ASN C O    1 
ATOM   5023  C  CB   . ASN C 1 263 ? 83.130  -29.706 33.369  1.00 63.68  ? 470 ASN C CB   1 
ATOM   5024  C  CG   . ASN C 1 263 ? 82.135  -30.340 32.426  1.00 65.99  ? 470 ASN C CG   1 
ATOM   5025  O  OD1  . ASN C 1 263 ? 81.253  -29.673 31.912  1.00 67.39  ? 470 ASN C OD1  1 
ATOM   5026  N  ND2  . ASN C 1 263 ? 82.263  -31.636 32.208  1.00 60.77  ? 470 ASN C ND2  1 
ATOM   5027  N  N    . PRO C 1 264 ? 85.548  -27.454 31.543  1.00 61.64  ? 471 PRO C N    1 
ATOM   5028  C  CA   . PRO C 1 264 ? 86.258  -27.294 30.271  1.00 61.21  ? 471 PRO C CA   1 
ATOM   5029  C  C    . PRO C 1 264 ? 86.824  -28.556 29.609  1.00 61.37  ? 471 PRO C C    1 
ATOM   5030  O  O    . PRO C 1 264 ? 86.862  -28.587 28.406  1.00 59.72  ? 471 PRO C O    1 
ATOM   5031  C  CB   . PRO C 1 264 ? 87.381  -26.342 30.690  1.00 59.68  ? 471 PRO C CB   1 
ATOM   5032  C  CG   . PRO C 1 264 ? 86.768  -25.533 31.788  1.00 59.66  ? 471 PRO C CG   1 
ATOM   5033  C  CD   . PRO C 1 264 ? 86.091  -26.605 32.601  1.00 55.42  ? 471 PRO C CD   1 
ATOM   5034  N  N    . LYS C 1 265 ? 87.240  -29.544 30.394  1.00 64.98  ? 472 LYS C N    1 
ATOM   5035  C  CA   . LYS C 1 265 ? 87.892  -30.745 29.821  1.00 62.36  ? 472 LYS C CA   1 
ATOM   5036  C  C    . LYS C 1 265 ? 86.861  -31.840 29.563  1.00 66.21  ? 472 LYS C C    1 
ATOM   5037  O  O    . LYS C 1 265 ? 87.198  -32.785 28.851  1.00 66.89  ? 472 LYS C O    1 
ATOM   5038  C  CB   . LYS C 1 265 ? 88.968  -31.241 30.783  1.00 66.59  ? 472 LYS C CB   1 
ATOM   5039  C  CG   . LYS C 1 265 ? 90.247  -30.420 30.822  1.00 65.70  ? 472 LYS C CG   1 
ATOM   5040  C  CD   . LYS C 1 265 ? 91.405  -31.182 31.420  1.00 62.13  ? 472 LYS C CD   1 
ATOM   5041  C  CE   . LYS C 1 265 ? 92.729  -30.469 31.258  1.00 70.35  ? 472 LYS C CE   1 
ATOM   5042  N  NZ   . LYS C 1 265 ? 93.177  -29.855 32.530  1.00 78.01  ? 472 LYS C NZ   1 
ATOM   5043  N  N    . GLY C 1 266 ? 85.659  -31.710 30.121  1.00 65.33  ? 473 GLY C N    1 
ATOM   5044  C  CA   . GLY C 1 266 ? 84.617  -32.738 29.964  1.00 65.60  ? 473 GLY C CA   1 
ATOM   5045  C  C    . GLY C 1 266 ? 84.775  -33.826 30.996  1.00 67.88  ? 473 GLY C C    1 
ATOM   5046  O  O    . GLY C 1 266 ? 84.037  -34.813 30.919  1.00 70.40  ? 473 GLY C O    1 
ATOM   5047  N  N    . ASP C 1 267 ? 85.688  -33.634 31.940  1.00 72.15  ? 474 ASP C N    1 
ATOM   5048  C  CA   . ASP C 1 267 ? 85.981  -34.650 32.978  1.00 68.89  ? 474 ASP C CA   1 
ATOM   5049  C  C    . ASP C 1 267 ? 85.085  -34.458 34.192  1.00 72.53  ? 474 ASP C C    1 
ATOM   5050  O  O    . ASP C 1 267 ? 85.290  -35.174 35.177  1.00 75.21  ? 474 ASP C O    1 
ATOM   5051  C  CB   . ASP C 1 267 ? 87.437  -34.535 33.425  1.00 67.98  ? 474 ASP C CB   1 
ATOM   5052  C  CG   . ASP C 1 267 ? 87.938  -33.120 33.685  1.00 74.77  ? 474 ASP C CG   1 
ATOM   5053  O  OD1  . ASP C 1 267 ? 87.115  -32.186 33.755  1.00 69.94  ? 474 ASP C OD1  1 
ATOM   5054  O  OD2  . ASP C 1 267 ? 89.163  -32.963 33.818  1.00 77.87  ? 474 ASP C OD2  1 
ATOM   5055  N  N    . GLY C 1 268 ? 84.129  -33.536 34.130  1.00 68.76  ? 475 GLY C N    1 
ATOM   5056  C  CA   . GLY C 1 268 ? 83.383  -33.276 35.336  1.00 67.21  ? 475 GLY C CA   1 
ATOM   5057  C  C    . GLY C 1 268 ? 84.126  -32.477 36.380  1.00 68.74  ? 475 GLY C C    1 
ATOM   5058  O  O    . GLY C 1 268 ? 83.681  -32.429 37.533  1.00 66.31  ? 475 GLY C O    1 
ATOM   5059  N  N    . LYS C 1 269 ? 85.248  -31.855 36.024  1.00 67.02  ? 476 LYS C N    1 
ATOM   5060  C  CA   . LYS C 1 269 ? 85.928  -30.914 36.914  1.00 70.69  ? 476 LYS C CA   1 
ATOM   5061  C  C    . LYS C 1 269 ? 85.331  -29.535 36.646  1.00 67.52  ? 476 LYS C C    1 
ATOM   5062  O  O    . LYS C 1 269 ? 85.728  -28.849 35.698  1.00 66.49  ? 476 LYS C O    1 
ATOM   5063  N  N    . TRP C 1 270 ? 84.379  -29.127 37.491  1.00 66.57  ? 477 TRP C N    1 
ATOM   5064  C  CA   . TRP C 1 270 ? 83.547  -27.954 37.240  1.00 65.96  ? 477 TRP C CA   1 
ATOM   5065  C  C    . TRP C 1 270 ? 84.108  -26.705 37.911  1.00 66.25  ? 477 TRP C C    1 
ATOM   5066  O  O    . TRP C 1 270 ? 84.657  -26.770 39.017  1.00 67.87  ? 477 TRP C O    1 
ATOM   5067  C  CB   . TRP C 1 270 ? 82.119  -28.199 37.742  1.00 64.34  ? 477 TRP C CB   1 
ATOM   5068  C  CG   . TRP C 1 270 ? 81.245  -29.054 36.828  1.00 68.91  ? 477 TRP C CG   1 
ATOM   5069  C  CD1  . TRP C 1 270 ? 81.074  -30.409 36.884  1.00 67.97  ? 477 TRP C CD1  1 
ATOM   5070  C  CD2  . TRP C 1 270 ? 80.422  -28.596 35.741  1.00 66.03  ? 477 TRP C CD2  1 
ATOM   5071  N  NE1  . TRP C 1 270 ? 80.204  -30.820 35.900  1.00 65.34  ? 477 TRP C NE1  1 
ATOM   5072  C  CE2  . TRP C 1 270 ? 79.790  -29.727 35.188  1.00 66.32  ? 477 TRP C CE2  1 
ATOM   5073  C  CE3  . TRP C 1 270 ? 80.170  -27.344 35.177  1.00 62.86  ? 477 TRP C CE3  1 
ATOM   5074  C  CZ2  . TRP C 1 270 ? 78.923  -29.639 34.106  1.00 64.57  ? 477 TRP C CZ2  1 
ATOM   5075  C  CZ3  . TRP C 1 270 ? 79.306  -27.262 34.118  1.00 64.68  ? 477 TRP C CZ3  1 
ATOM   5076  C  CH2  . TRP C 1 270 ? 78.696  -28.397 33.587  1.00 62.43  ? 477 TRP C CH2  1 
ATOM   5077  N  N    . CYS C 1 271 ? 83.931  -25.557 37.247  1.00 63.11  ? 478 CYS C N    1 
ATOM   5078  C  CA   . CYS C 1 271 ? 84.240  -24.252 37.818  1.00 60.73  ? 478 CYS C CA   1 
ATOM   5079  C  C    . CYS C 1 271 ? 83.121  -23.269 37.506  1.00 65.97  ? 478 CYS C C    1 
ATOM   5080  O  O    . CYS C 1 271 ? 82.427  -23.398 36.490  1.00 62.99  ? 478 CYS C O    1 
ATOM   5081  C  CB   . CYS C 1 271 ? 85.556  -23.695 37.277  1.00 58.28  ? 478 CYS C CB   1 
ATOM   5082  S  SG   . CYS C 1 271 ? 87.008  -24.705 37.715  1.00 72.02  ? 478 CYS C SG   1 
ATOM   5083  N  N    . LYS C 1 272 ? 82.971  -22.265 38.385  1.00 67.04  ? 479 LYS C N    1 
ATOM   5084  C  CA   . LYS C 1 272 ? 82.067  -21.132 38.178  1.00 57.99  ? 479 LYS C CA   1 
ATOM   5085  C  C    . LYS C 1 272 ? 82.853  -19.930 37.674  1.00 63.27  ? 479 LYS C C    1 
ATOM   5086  O  O    . LYS C 1 272 ? 83.775  -19.459 38.349  1.00 69.46  ? 479 LYS C O    1 
ATOM   5087  C  CB   . LYS C 1 272 ? 81.338  -20.751 39.465  1.00 62.01  ? 479 LYS C CB   1 
ATOM   5088  C  CG   . LYS C 1 272 ? 80.233  -19.719 39.239  1.00 66.60  ? 479 LYS C CG   1 
ATOM   5089  C  CD   . LYS C 1 272 ? 80.057  -18.730 40.402  1.00 62.58  ? 479 LYS C CD   1 
ATOM   5090  C  CE   . LYS C 1 272 ? 79.617  -19.407 41.675  1.00 71.30  ? 479 LYS C CE   1 
ATOM   5091  N  NZ   . LYS C 1 272 ? 80.192  -18.748 42.909  1.00 85.85  ? 479 LYS C NZ   1 
ATOM   5092  N  N    . PHE C 1 273 ? 82.478  -19.425 36.501  1.00 66.84  ? 480 PHE C N    1 
ATOM   5093  C  CA   . PHE C 1 273 ? 83.068  -18.221 35.916  1.00 58.36  ? 480 PHE C CA   1 
ATOM   5094  C  C    . PHE C 1 273 ? 82.074  -17.087 36.101  1.00 59.24  ? 480 PHE C C    1 
ATOM   5095  O  O    . PHE C 1 273 ? 80.988  -17.117 35.516  1.00 61.76  ? 480 PHE C O    1 
ATOM   5096  C  CB   . PHE C 1 273 ? 83.374  -18.416 34.439  1.00 58.52  ? 480 PHE C CB   1 
ATOM   5097  C  CG   . PHE C 1 273 ? 84.326  -19.528 34.155  1.00 56.39  ? 480 PHE C CG   1 
ATOM   5098  C  CD1  . PHE C 1 273 ? 83.934  -20.842 34.302  1.00 53.83  ? 480 PHE C CD1  1 
ATOM   5099  C  CD2  . PHE C 1 273 ? 85.610  -19.253 33.704  1.00 56.99  ? 480 PHE C CD2  1 
ATOM   5100  C  CE1  . PHE C 1 273 ? 84.809  -21.871 34.029  1.00 60.56  ? 480 PHE C CE1  1 
ATOM   5101  C  CE2  . PHE C 1 273 ? 86.495  -20.268 33.436  1.00 58.89  ? 480 PHE C CE2  1 
ATOM   5102  C  CZ   . PHE C 1 273 ? 86.098  -21.586 33.593  1.00 60.80  ? 480 PHE C CZ   1 
ATOM   5103  N  N    . ASP C 1 274 ? 82.410  -16.166 37.007  1.00 63.32  ? 481 ASP C N    1 
ATOM   5104  C  CA   . ASP C 1 274 ? 81.552  -14.991 37.300  1.00 60.43  ? 481 ASP C CA   1 
ATOM   5105  C  C    . ASP C 1 274 ? 82.398  -13.768 37.000  1.00 67.01  ? 481 ASP C C    1 
ATOM   5106  O  O    . ASP C 1 274 ? 83.016  -13.236 37.937  1.00 76.71  ? 481 ASP C O    1 
ATOM   5107  C  CB   . ASP C 1 274 ? 81.070  -14.968 38.749  1.00 54.42  ? 481 ASP C CB   1 
ATOM   5108  C  CG   . ASP C 1 274 ? 80.050  -13.897 39.086  1.00 63.32  ? 481 ASP C CG   1 
ATOM   5109  O  OD1  . ASP C 1 274 ? 79.743  -13.078 38.212  1.00 60.21  ? 481 ASP C OD1  1 
ATOM   5110  O  OD2  . ASP C 1 274 ? 79.567  -13.899 40.231  1.00 69.34  ? 481 ASP C OD2  1 
ATOM   5111  N  N    . ASP C 1 275 ? 82.427  -13.370 35.737  1.00 64.87  ? 482 ASP C N    1 
ATOM   5112  C  CA   . ASP C 1 275 ? 83.233  -12.202 35.318  1.00 67.56  ? 482 ASP C CA   1 
ATOM   5113  C  C    . ASP C 1 275 ? 84.677  -12.393 35.800  1.00 75.68  ? 482 ASP C C    1 
ATOM   5114  O  O    . ASP C 1 275 ? 85.336  -13.272 35.247  1.00 68.96  ? 482 ASP C O    1 
ATOM   5115  C  CB   . ASP C 1 275 ? 82.555  -10.894 35.738  1.00 64.74  ? 482 ASP C CB   1 
ATOM   5116  C  CG   . ASP C 1 275 ? 81.198  -10.660 35.102  1.00 66.74  ? 482 ASP C CG   1 
ATOM   5117  O  OD1  . ASP C 1 275 ? 80.886  -11.342 34.114  1.00 69.44  ? 482 ASP C OD1  1 
ATOM   5118  O  OD2  . ASP C 1 275 ? 80.469  -9.793  35.601  1.00 69.36  ? 482 ASP C OD2  1 
ATOM   5119  N  N    . ASP C 1 276 ? 85.120  -11.630 36.803  1.00 75.72  ? 483 ASP C N    1 
ATOM   5120  C  CA   . ASP C 1 276 ? 86.537  -11.657 37.266  1.00 73.24  ? 483 ASP C CA   1 
ATOM   5121  C  C    . ASP C 1 276 ? 86.852  -12.876 38.126  1.00 73.01  ? 483 ASP C C    1 
ATOM   5122  O  O    . ASP C 1 276 ? 88.033  -13.234 38.195  1.00 72.19  ? 483 ASP C O    1 
ATOM   5123  C  CB   . ASP C 1 276 ? 86.859  -10.408 38.087  1.00 72.23  ? 483 ASP C CB   1 
ATOM   5124  C  CG   . ASP C 1 276 ? 85.637  -9.619  38.519  1.00 79.22  ? 483 ASP C CG   1 
ATOM   5125  O  OD1  . ASP C 1 276 ? 84.974  -10.052 39.476  1.00 81.44  ? 483 ASP C OD1  1 
ATOM   5126  O  OD2  . ASP C 1 276 ? 85.358  -8.582  37.889  1.00 78.85  ? 483 ASP C OD2  1 
ATOM   5127  N  N    . VAL C 1 277 ? 85.847  -13.496 38.738  1.00 70.35  ? 484 VAL C N    1 
ATOM   5128  C  CA   . VAL C 1 277 ? 86.117  -14.592 39.712  1.00 69.48  ? 484 VAL C CA   1 
ATOM   5129  C  C    . VAL C 1 277 ? 85.885  -15.975 39.103  1.00 70.97  ? 484 VAL C C    1 
ATOM   5130  O  O    . VAL C 1 277 ? 84.757  -16.254 38.678  1.00 69.33  ? 484 VAL C O    1 
ATOM   5131  C  CB   . VAL C 1 277 ? 85.260  -14.406 40.977  1.00 73.98  ? 484 VAL C CB   1 
ATOM   5132  C  CG1  . VAL C 1 277 ? 85.681  -15.350 42.090  1.00 67.55  ? 484 VAL C CG1  1 
ATOM   5133  C  CG2  . VAL C 1 277 ? 85.256  -12.967 41.465  1.00 68.50  ? 484 VAL C CG2  1 
ATOM   5134  N  N    . VAL C 1 278 ? 86.917  -16.812 39.094  1.00 64.52  ? 485 VAL C N    1 
ATOM   5135  C  CA   . VAL C 1 278 ? 86.750  -18.219 38.641  1.00 63.35  ? 485 VAL C CA   1 
ATOM   5136  C  C    . VAL C 1 278 ? 87.014  -19.110 39.856  1.00 69.26  ? 485 VAL C C    1 
ATOM   5137  O  O    . VAL C 1 278 ? 88.105  -19.001 40.426  1.00 70.22  ? 485 VAL C O    1 
ATOM   5138  C  CB   . VAL C 1 278 ? 87.674  -18.556 37.459  1.00 60.86  ? 485 VAL C CB   1 
ATOM   5139  C  CG1  . VAL C 1 278 ? 87.520  -20.000 37.013  1.00 57.73  ? 485 VAL C CG1  1 
ATOM   5140  C  CG2  . VAL C 1 278 ? 87.451  -17.613 36.297  1.00 61.43  ? 485 VAL C CG2  1 
ATOM   5141  N  N    . SER C 1 279 ? 86.045  -19.936 40.247  1.00 66.09  ? 486 SER C N    1 
ATOM   5142  C  CA   . SER C 1 279 ? 86.192  -20.771 41.466  1.00 62.89  ? 486 SER C CA   1 
ATOM   5143  C  C    . SER C 1 279 ? 85.756  -22.197 41.187  1.00 67.53  ? 486 SER C C    1 
ATOM   5144  O  O    . SER C 1 279 ? 84.766  -22.368 40.482  1.00 74.19  ? 486 SER C O    1 
ATOM   5145  C  CB   . SER C 1 279 ? 85.378  -20.218 42.588  1.00 65.44  ? 486 SER C CB   1 
ATOM   5146  O  OG   . SER C 1 279 ? 83.997  -20.502 42.420  1.00 72.22  ? 486 SER C OG   1 
ATOM   5147  N  N    . ARG C 1 280 ? 86.432  -23.182 41.774  1.00 59.58  ? 487 ARG C N    1 
ATOM   5148  C  CA   . ARG C 1 280 ? 85.953  -24.539 41.609  1.00 62.75  ? 487 ARG C CA   1 
ATOM   5149  C  C    . ARG C 1 280 ? 84.592  -24.686 42.272  1.00 66.65  ? 487 ARG C C    1 
ATOM   5150  O  O    . ARG C 1 280 ? 84.196  -23.891 43.130  1.00 65.99  ? 487 ARG C O    1 
ATOM   5151  C  CB   . ARG C 1 280 ? 86.955  -25.546 42.160  1.00 63.77  ? 487 ARG C CB   1 
ATOM   5152  C  CG   . ARG C 1 280 ? 87.830  -26.123 41.060  1.00 66.70  ? 487 ARG C CG   1 
ATOM   5153  C  CD   . ARG C 1 280 ? 88.215  -27.549 41.357  1.00 74.39  ? 487 ARG C CD   1 
ATOM   5154  N  NE   . ARG C 1 280 ? 87.435  -28.520 40.592  1.00 78.29  ? 487 ARG C NE   1 
ATOM   5155  C  CZ   . ARG C 1 280 ? 87.318  -29.799 40.941  1.00 82.95  ? 487 ARG C CZ   1 
ATOM   5156  N  NH1  . ARG C 1 280 ? 87.925  -30.237 42.035  1.00 80.21  ? 487 ARG C NH1  1 
ATOM   5157  N  NH2  . ARG C 1 280 ? 86.607  -30.642 40.203  1.00 82.74  ? 487 ARG C NH2  1 
ATOM   5158  N  N    . CYS C 1 281 ? 83.840  -25.680 41.813  1.00 66.87  ? 488 CYS C N    1 
ATOM   5159  C  CA   . CYS C 1 281 ? 82.499  -25.893 42.324  1.00 60.12  ? 488 CYS C CA   1 
ATOM   5160  C  C    . CYS C 1 281 ? 82.163  -27.368 42.196  1.00 64.07  ? 488 CYS C C    1 
ATOM   5161  O  O    . CYS C 1 281 ? 82.873  -28.144 41.545  1.00 66.06  ? 488 CYS C O    1 
ATOM   5162  C  CB   . CYS C 1 281 ? 81.484  -24.977 41.611  1.00 64.46  ? 488 CYS C CB   1 
ATOM   5163  S  SG   . CYS C 1 281 ? 81.193  -25.349 39.873  1.00 58.83  ? 488 CYS C SG   1 
ATOM   5164  N  N    . THR C 1 282 ? 81.096  -27.753 42.877  1.00 62.85  ? 489 THR C N    1 
ATOM   5165  C  CA   . THR C 1 282 ? 80.611  -29.116 42.811  1.00 67.13  ? 489 THR C CA   1 
ATOM   5166  C  C    . THR C 1 282 ? 79.761  -29.322 41.551  1.00 71.81  ? 489 THR C C    1 
ATOM   5167  O  O    . THR C 1 282 ? 79.289  -28.368 40.920  1.00 68.22  ? 489 THR C O    1 
ATOM   5168  C  CB   . THR C 1 282 ? 79.800  -29.444 44.072  1.00 63.15  ? 489 THR C CB   1 
ATOM   5169  O  OG1  . THR C 1 282 ? 78.555  -28.749 44.040  1.00 66.08  ? 489 THR C OG1  1 
ATOM   5170  C  CG2  . THR C 1 282 ? 80.534  -29.009 45.302  1.00 67.24  ? 489 THR C CG2  1 
ATOM   5171  N  N    . LYS C 1 283 ? 79.584  -30.595 41.174  1.00 71.01  ? 490 LYS C N    1 
ATOM   5172  C  CA   . LYS C 1 283 ? 78.579  -30.923 40.170  1.00 68.90  ? 490 LYS C CA   1 
ATOM   5173  C  C    . LYS C 1 283 ? 77.208  -30.449 40.631  1.00 68.79  ? 490 LYS C C    1 
ATOM   5174  O  O    . LYS C 1 283 ? 76.495  -29.746 39.900  1.00 65.05  ? 490 LYS C O    1 
ATOM   5175  C  CB   . LYS C 1 283 ? 78.560  -32.434 39.894  1.00 68.00  ? 490 LYS C CB   1 
ATOM   5176  C  CG   . LYS C 1 283 ? 79.634  -32.929 38.951  1.00 68.05  ? 490 LYS C CG   1 
ATOM   5177  C  CD   . LYS C 1 283 ? 79.540  -34.431 38.716  1.00 70.39  ? 490 LYS C CD   1 
ATOM   5178  C  CE   . LYS C 1 283 ? 80.678  -34.887 37.790  1.00 71.09  ? 490 LYS C CE   1 
ATOM   5179  N  NZ   . LYS C 1 283 ? 80.790  -36.367 37.602  1.00 64.86  ? 490 LYS C NZ   1 
ATOM   5180  N  N    . GLU C 1 284 ? 76.832  -30.816 41.859  1.00 67.40  ? 491 GLU C N    1 
ATOM   5181  C  CA   . GLU C 1 284 ? 75.595  -30.305 42.436  1.00 69.86  ? 491 GLU C CA   1 
ATOM   5182  C  C    . GLU C 1 284 ? 75.529  -28.786 42.306  1.00 67.89  ? 491 GLU C C    1 
ATOM   5183  O  O    . GLU C 1 284 ? 74.462  -28.225 42.030  1.00 68.78  ? 491 GLU C O    1 
ATOM   5184  C  CB   . GLU C 1 284 ? 75.476  -30.746 43.900  1.00 61.62  ? 491 GLU C CB   1 
ATOM   5185  N  N    . GLU C 1 285 ? 76.658  -28.098 42.331  1.00 66.00  ? 492 GLU C N    1 
ATOM   5186  C  CA   . GLU C 1 285 ? 76.590  -26.619 42.288  1.00 63.66  ? 492 GLU C CA   1 
ATOM   5187  C  C    . GLU C 1 285 ? 76.250  -26.165 40.870  1.00 69.88  ? 492 GLU C C    1 
ATOM   5188  O  O    . GLU C 1 285 ? 75.542  -25.157 40.736  1.00 72.26  ? 492 GLU C O    1 
ATOM   5189  N  N    . ALA C 1 286 ? 76.714  -26.891 39.859  1.00 66.51  ? 493 ALA C N    1 
ATOM   5190  C  CA   . ALA C 1 286 ? 76.538  -26.456 38.459  1.00 61.74  ? 493 ALA C CA   1 
ATOM   5191  C  C    . ALA C 1 286 ? 75.241  -26.975 37.855  1.00 62.74  ? 493 ALA C C    1 
ATOM   5192  O  O    . ALA C 1 286 ? 74.719  -26.313 36.961  1.00 59.28  ? 493 ALA C O    1 
ATOM   5193  C  CB   . ALA C 1 286 ? 77.702  -26.980 37.680  1.00 55.41  ? 493 ALA C CB   1 
ATOM   5194  N  N    . ILE C 1 287 ? 74.762  -28.125 38.313  1.00 61.35  ? 494 ILE C N    1 
ATOM   5195  C  CA   . ILE C 1 287 ? 73.581  -28.752 37.663  1.00 58.16  ? 494 ILE C CA   1 
ATOM   5196  C  C    . ILE C 1 287 ? 72.349  -28.561 38.542  1.00 62.85  ? 494 ILE C C    1 
ATOM   5197  O  O    . ILE C 1 287 ? 71.614  -27.611 38.278  1.00 61.12  ? 494 ILE C O    1 
ATOM   5198  C  CB   . ILE C 1 287 ? 73.894  -30.234 37.379  1.00 57.42  ? 494 ILE C CB   1 
ATOM   5199  C  CG1  . ILE C 1 287 ? 75.269  -30.402 36.727  1.00 58.35  ? 494 ILE C CG1  1 
ATOM   5200  C  CG2  . ILE C 1 287 ? 72.810  -30.888 36.544  1.00 59.15  ? 494 ILE C CG2  1 
ATOM   5201  C  CD1  . ILE C 1 287 ? 75.843  -31.790 36.852  1.00 66.76  ? 494 ILE C CD1  1 
ATOM   5202  N  N    . GLU C 1 288 ? 72.171  -29.394 39.563  1.00 60.39  ? 495 GLU C N    1 
ATOM   5203  C  CA   . GLU C 1 288 ? 70.950  -29.382 40.410  1.00 57.82  ? 495 GLU C CA   1 
ATOM   5204  C  C    . GLU C 1 288 ? 70.639  -27.993 40.979  1.00 64.28  ? 495 GLU C C    1 
ATOM   5205  O  O    . GLU C 1 288 ? 69.458  -27.664 41.084  1.00 67.94  ? 495 GLU C O    1 
ATOM   5206  C  CB   . GLU C 1 288 ? 71.112  -30.447 41.491  1.00 63.63  ? 495 GLU C CB   1 
ATOM   5207  C  CG   . GLU C 1 288 ? 70.940  -31.861 40.970  1.00 58.91  ? 495 GLU C CG   1 
ATOM   5208  C  CD   . GLU C 1 288 ? 72.201  -32.578 40.515  1.00 66.46  ? 495 GLU C CD   1 
ATOM   5209  O  OE1  . GLU C 1 288 ? 72.101  -33.768 40.176  1.00 73.79  ? 495 GLU C OE1  1 
ATOM   5210  O  OE2  . GLU C 1 288 ? 73.273  -31.950 40.495  1.00 66.62  ? 495 GLU C OE2  1 
ATOM   5211  N  N    . HIS C 1 289 ? 71.652  -27.225 41.359  1.00 69.89  ? 496 HIS C N    1 
ATOM   5212  C  CA   . HIS C 1 289 ? 71.406  -25.914 41.955  1.00 64.75  ? 496 HIS C CA   1 
ATOM   5213  C  C    . HIS C 1 289 ? 70.868  -24.900 40.956  1.00 68.13  ? 496 HIS C C    1 
ATOM   5214  O  O    . HIS C 1 289 ? 70.367  -23.852 41.373  1.00 71.63  ? 496 HIS C O    1 
ATOM   5215  C  CB   . HIS C 1 289 ? 72.685  -25.383 42.602  1.00 67.24  ? 496 HIS C CB   1 
ATOM   5216  C  CG   . HIS C 1 289 ? 73.004  -26.018 43.926  1.00 73.92  ? 496 HIS C CG   1 
ATOM   5217  N  ND1  . HIS C 1 289 ? 73.970  -25.523 44.777  1.00 71.59  ? 496 HIS C ND1  1 
ATOM   5218  C  CD2  . HIS C 1 289 ? 72.482  -27.107 44.544  1.00 71.40  ? 496 HIS C CD2  1 
ATOM   5219  C  CE1  . HIS C 1 289 ? 74.033  -26.283 45.857  1.00 65.80  ? 496 HIS C CE1  1 
ATOM   5220  N  NE2  . HIS C 1 289 ? 73.143  -27.252 45.740  1.00 65.24  ? 496 HIS C NE2  1 
ATOM   5221  N  N    . ASN C 1 290 ? 70.931  -25.191 39.657  1.00 65.46  ? 497 ASN C N    1 
ATOM   5222  C  CA   . ASN C 1 290 ? 70.403  -24.297 38.636  1.00 64.61  ? 497 ASN C CA   1 
ATOM   5223  C  C    . ASN C 1 290 ? 69.110  -24.811 38.013  1.00 62.26  ? 497 ASN C C    1 
ATOM   5224  O  O    . ASN C 1 290 ? 68.680  -24.282 36.982  1.00 64.37  ? 497 ASN C O    1 
ATOM   5225  C  CB   . ASN C 1 290 ? 71.456  -24.067 37.557  1.00 67.90  ? 497 ASN C CB   1 
ATOM   5226  C  CG   . ASN C 1 290 ? 72.649  -23.298 38.074  1.00 63.72  ? 497 ASN C CG   1 
ATOM   5227  O  OD1  . ASN C 1 290 ? 72.521  -22.158 38.553  1.00 68.43  ? 497 ASN C OD1  1 
ATOM   5228  N  ND2  . ASN C 1 290 ? 73.823  -23.916 37.989  1.00 61.25  ? 497 ASN C ND2  1 
ATOM   5229  N  N    . TYR C 1 291 ? 68.475  -25.813 38.630  1.00 56.33  ? 498 TYR C N    1 
ATOM   5230  C  CA   . TYR C 1 291 ? 67.229  -26.375 38.127  1.00 60.28  ? 498 TYR C CA   1 
ATOM   5231  C  C    . TYR C 1 291 ? 66.069  -25.398 38.227  1.00 58.85  ? 498 TYR C C    1 
ATOM   5232  O  O    . TYR C 1 291 ? 65.061  -25.578 37.533  1.00 54.47  ? 498 TYR C O    1 
ATOM   5233  C  CB   . TYR C 1 291 ? 66.872  -27.645 38.900  1.00 57.33  ? 498 TYR C CB   1 
ATOM   5234  C  CG   . TYR C 1 291 ? 67.609  -28.874 38.464  1.00 58.11  ? 498 TYR C CG   1 
ATOM   5235  C  CD1  . TYR C 1 291 ? 68.724  -28.776 37.649  1.00 59.99  ? 498 TYR C CD1  1 
ATOM   5236  C  CD2  . TYR C 1 291 ? 67.180  -30.147 38.853  1.00 60.74  ? 498 TYR C CD2  1 
ATOM   5237  C  CE1  . TYR C 1 291 ? 69.411  -29.908 37.239  1.00 61.47  ? 498 TYR C CE1  1 
ATOM   5238  C  CE2  . TYR C 1 291 ? 67.864  -31.287 38.441  1.00 59.76  ? 498 TYR C CE2  1 
ATOM   5239  C  CZ   . TYR C 1 291 ? 68.977  -31.152 37.634  1.00 59.69  ? 498 TYR C CZ   1 
ATOM   5240  O  OH   . TYR C 1 291 ? 69.680  -32.250 37.216  1.00 61.74  ? 498 TYR C OH   1 
ATOM   5241  N  N    . GLY C 1 292 ? 66.188  -24.375 39.073  1.00 64.29  ? 499 GLY C N    1 
ATOM   5242  C  CA   . GLY C 1 292 ? 65.105  -23.438 39.307  1.00 64.39  ? 499 GLY C CA   1 
ATOM   5243  C  C    . GLY C 1 292 ? 64.205  -23.882 40.442  1.00 59.27  ? 499 GLY C C    1 
ATOM   5244  O  O    . GLY C 1 292 ? 64.433  -24.891 41.118  1.00 60.73  ? 499 GLY C O    1 
ATOM   5245  N  N    . GLY C 1 293 ? 63.142  -23.118 40.665  1.00 59.87  ? 500 GLY C N    1 
ATOM   5246  C  CA   . GLY C 1 293 ? 62.189  -23.463 41.733  1.00 62.84  ? 500 GLY C CA   1 
ATOM   5247  C  C    . GLY C 1 293 ? 61.843  -22.267 42.597  1.00 77.57  ? 500 GLY C C    1 
ATOM   5248  O  O    . GLY C 1 293 ? 60.647  -22.118 42.910  1.00 88.37  ? 500 GLY C O    1 
ATOM   5249  N  N    . CYS C 1 303 ? 64.967  -17.345 41.644  1.00 70.13  ? 510 CYS C N    1 
ATOM   5250  C  CA   . CYS C 1 303 ? 65.087  -16.490 40.467  1.00 67.14  ? 510 CYS C CA   1 
ATOM   5251  C  C    . CYS C 1 303 ? 66.433  -16.694 39.762  1.00 64.32  ? 510 CYS C C    1 
ATOM   5252  O  O    . CYS C 1 303 ? 66.755  -15.998 38.797  1.00 65.12  ? 510 CYS C O    1 
ATOM   5253  C  CB   . CYS C 1 303 ? 64.929  -15.025 40.855  1.00 64.39  ? 510 CYS C CB   1 
ATOM   5254  S  SG   . CYS C 1 303 ? 66.399  -14.405 41.720  1.00 79.91  ? 510 CYS C SG   1 
ATOM   5255  N  N    . THR C 1 304 ? 67.229  -17.628 40.265  1.00 59.85  ? 511 THR C N    1 
ATOM   5256  C  CA   . THR C 1 304 ? 68.512  -17.985 39.672  1.00 65.53  ? 511 THR C CA   1 
ATOM   5257  C  C    . THR C 1 304 ? 68.352  -19.359 39.033  1.00 68.26  ? 511 THR C C    1 
ATOM   5258  O  O    . THR C 1 304 ? 67.964  -20.317 39.713  1.00 67.94  ? 511 THR C O    1 
ATOM   5259  C  CB   . THR C 1 304 ? 69.628  -18.001 40.728  1.00 66.77  ? 511 THR C CB   1 
ATOM   5260  O  OG1  . THR C 1 304 ? 69.768  -16.701 41.312  1.00 67.64  ? 511 THR C OG1  1 
ATOM   5261  C  CG2  . THR C 1 304 ? 70.953  -18.404 40.121  1.00 55.15  ? 511 THR C CG2  1 
ATOM   5262  N  N    . ASN C 1 305 ? 68.625  -19.456 37.731  1.00 65.29  ? 512 ASN C N    1 
ATOM   5263  C  CA   . ASN C 1 305 ? 68.445  -20.739 37.060  1.00 66.13  ? 512 ASN C CA   1 
ATOM   5264  C  C    . ASN C 1 305 ? 69.144  -20.725 35.708  1.00 59.63  ? 512 ASN C C    1 
ATOM   5265  O  O    . ASN C 1 305 ? 69.440  -19.669 35.144  1.00 55.84  ? 512 ASN C O    1 
ATOM   5266  C  CB   . ASN C 1 305 ? 66.964  -21.057 36.887  1.00 62.41  ? 512 ASN C CB   1 
ATOM   5267  C  CG   . ASN C 1 305 ? 66.170  -19.836 36.516  1.00 63.74  ? 512 ASN C CG   1 
ATOM   5268  O  OD1  . ASN C 1 305 ? 66.412  -19.244 35.470  1.00 66.39  ? 512 ASN C OD1  1 
ATOM   5269  N  ND2  . ASN C 1 305 ? 65.237  -19.428 37.379  1.00 64.20  ? 512 ASN C ND2  1 
ATOM   5270  N  N    . ALA C 1 306 ? 69.391  -21.925 35.200  1.00 62.67  ? 513 ALA C N    1 
ATOM   5271  C  CA   . ALA C 1 306 ? 69.962  -22.094 33.872  1.00 61.88  ? 513 ALA C CA   1 
ATOM   5272  C  C    . ALA C 1 306 ? 69.071  -21.474 32.803  1.00 51.03  ? 513 ALA C C    1 
ATOM   5273  O  O    . ALA C 1 306 ? 67.863  -21.705 32.778  1.00 51.32  ? 513 ALA C O    1 
ATOM   5274  C  CB   . ALA C 1 306 ? 70.155  -23.584 33.589  1.00 58.67  ? 513 ALA C CB   1 
ATOM   5275  N  N    . TYR C 1 307 ? 69.694  -20.785 31.846  1.00 48.68  ? 514 TYR C N    1 
ATOM   5276  C  CA   . TYR C 1 307 ? 68.964  -20.226 30.681  1.00 53.25  ? 514 TYR C CA   1 
ATOM   5277  C  C    . TYR C 1 307 ? 69.468  -20.908 29.407  1.00 54.44  ? 514 TYR C C    1 
ATOM   5278  O  O    . TYR C 1 307 ? 68.659  -21.229 28.545  1.00 55.55  ? 514 TYR C O    1 
ATOM   5279  C  CB   . TYR C 1 307 ? 69.196  -18.721 30.572  1.00 47.84  ? 514 TYR C CB   1 
ATOM   5280  C  CG   . TYR C 1 307 ? 68.602  -18.021 29.377  1.00 52.77  ? 514 TYR C CG   1 
ATOM   5281  C  CD1  . TYR C 1 307 ? 67.281  -18.207 29.013  1.00 51.38  ? 514 TYR C CD1  1 
ATOM   5282  C  CD2  . TYR C 1 307 ? 69.360  -17.141 28.626  1.00 50.36  ? 514 TYR C CD2  1 
ATOM   5283  C  CE1  . TYR C 1 307 ? 66.733  -17.552 27.924  1.00 47.52  ? 514 TYR C CE1  1 
ATOM   5284  C  CE2  . TYR C 1 307 ? 68.829  -16.476 27.536  1.00 49.77  ? 514 TYR C CE2  1 
ATOM   5285  C  CZ   . TYR C 1 307 ? 67.509  -16.681 27.185  1.00 55.13  ? 514 TYR C CZ   1 
ATOM   5286  O  OH   . TYR C 1 307 ? 66.970  -16.036 26.114  1.00 48.06  ? 514 TYR C OH   1 
ATOM   5287  N  N    . MET C 1 308 ? 70.780  -21.077 29.280  1.00 49.74  ? 515 MET C N    1 
ATOM   5288  C  CA   . MET C 1 308 ? 71.365  -21.753 28.093  1.00 52.59  ? 515 MET C CA   1 
ATOM   5289  C  C    . MET C 1 308 ? 72.160  -22.976 28.544  1.00 50.37  ? 515 MET C C    1 
ATOM   5290  O  O    . MET C 1 308 ? 72.698  -22.957 29.654  1.00 55.79  ? 515 MET C O    1 
ATOM   5291  C  CB   . MET C 1 308 ? 72.279  -20.820 27.299  1.00 55.24  ? 515 MET C CB   1 
ATOM   5292  C  CG   . MET C 1 308 ? 72.241  -21.045 25.809  1.00 52.79  ? 515 MET C CG   1 
ATOM   5293  S  SD   . MET C 1 308 ? 73.070  -19.707 24.935  1.00 57.01  ? 515 MET C SD   1 
ATOM   5294  C  CE   . MET C 1 308 ? 74.586  -20.521 24.439  1.00 54.24  ? 515 MET C CE   1 
ATOM   5295  N  N    . LEU C 1 309 ? 72.203  -24.006 27.706  1.00 50.11  ? 516 LEU C N    1 
ATOM   5296  C  CA   . LEU C 1 309 ? 72.914  -25.254 28.056  1.00 49.53  ? 516 LEU C CA   1 
ATOM   5297  C  C    . LEU C 1 309 ? 73.785  -25.684 26.880  1.00 49.30  ? 516 LEU C C    1 
ATOM   5298  O  O    . LEU C 1 309 ? 73.314  -25.629 25.746  1.00 51.91  ? 516 LEU C O    1 
ATOM   5299  C  CB   . LEU C 1 309 ? 71.884  -26.335 28.389  1.00 47.70  ? 516 LEU C CB   1 
ATOM   5300  C  CG   . LEU C 1 309 ? 71.139  -26.196 29.710  1.00 50.71  ? 516 LEU C CG   1 
ATOM   5301  C  CD1  . LEU C 1 309 ? 70.091  -27.285 29.831  1.00 50.55  ? 516 LEU C CD1  1 
ATOM   5302  C  CD2  . LEU C 1 309 ? 72.107  -26.265 30.873  1.00 54.61  ? 516 LEU C CD2  1 
ATOM   5303  N  N    . VAL C 1 310 ? 75.027  -26.057 27.151  1.00 51.35  ? 517 VAL C N    1 
ATOM   5304  C  CA   . VAL C 1 310 ? 75.909  -26.577 26.121  1.00 51.26  ? 517 VAL C CA   1 
ATOM   5305  C  C    . VAL C 1 310 ? 76.125  -28.043 26.418  1.00 56.94  ? 517 VAL C C    1 
ATOM   5306  O  O    . VAL C 1 310 ? 76.596  -28.391 27.511  1.00 59.05  ? 517 VAL C O    1 
ATOM   5307  C  CB   . VAL C 1 310 ? 77.242  -25.820 26.063  1.00 51.55  ? 517 VAL C CB   1 
ATOM   5308  C  CG1  . VAL C 1 310 ? 78.121  -26.403 24.957  1.00 44.73  ? 517 VAL C CG1  1 
ATOM   5309  C  CG2  . VAL C 1 310 ? 76.980  -24.331 25.799  1.00 46.49  ? 517 VAL C CG2  1 
ATOM   5310  N  N    . TYR C 1 311 ? 75.782  -28.875 25.433  1.00 53.58  ? 518 TYR C N    1 
ATOM   5311  C  CA   . TYR C 1 311 ? 76.049  -30.326 25.521  1.00 49.29  ? 518 TYR C CA   1 
ATOM   5312  C  C    . TYR C 1 311 ? 76.984  -30.673 24.363  1.00 53.62  ? 518 TYR C C    1 
ATOM   5313  O  O    . TYR C 1 311 ? 76.915  -30.029 23.317  1.00 54.06  ? 518 TYR C O    1 
ATOM   5314  C  CB   . TYR C 1 311 ? 74.755  -31.132 25.448  1.00 49.95  ? 518 TYR C CB   1 
ATOM   5315  C  CG   . TYR C 1 311 ? 73.950  -31.190 26.717  1.00 48.90  ? 518 TYR C CG   1 
ATOM   5316  C  CD1  . TYR C 1 311 ? 74.080  -32.245 27.600  1.00 44.21  ? 518 TYR C CD1  1 
ATOM   5317  C  CD2  . TYR C 1 311 ? 73.039  -30.197 27.023  1.00 52.93  ? 518 TYR C CD2  1 
ATOM   5318  C  CE1  . TYR C 1 311 ? 73.338  -32.303 28.766  1.00 50.40  ? 518 TYR C CE1  1 
ATOM   5319  C  CE2  . TYR C 1 311 ? 72.286  -30.242 28.181  1.00 50.47  ? 518 TYR C CE2  1 
ATOM   5320  C  CZ   . TYR C 1 311 ? 72.435  -31.298 29.056  1.00 47.78  ? 518 TYR C CZ   1 
ATOM   5321  O  OH   . TYR C 1 311 ? 71.689  -31.332 30.193  1.00 50.76  ? 518 TYR C OH   1 
ATOM   5322  N  N    . ILE C 1 312 ? 77.874  -31.634 24.565  1.00 48.98  ? 519 ILE C N    1 
ATOM   5323  C  CA   . ILE C 1 312 ? 78.816  -32.036 23.526  1.00 52.27  ? 519 ILE C CA   1 
ATOM   5324  C  C    . ILE C 1 312 ? 78.620  -33.519 23.258  1.00 53.99  ? 519 ILE C C    1 
ATOM   5325  O  O    . ILE C 1 312 ? 78.466  -34.319 24.190  1.00 58.22  ? 519 ILE C O    1 
ATOM   5326  C  CB   . ILE C 1 312 ? 80.292  -31.729 23.882  1.00 50.80  ? 519 ILE C CB   1 
ATOM   5327  C  CG1  . ILE C 1 312 ? 80.534  -30.227 24.010  1.00 53.96  ? 519 ILE C CG1  1 
ATOM   5328  C  CG2  . ILE C 1 312 ? 81.225  -32.223 22.782  1.00 54.59  ? 519 ILE C CG2  1 
ATOM   5329  C  CD1  . ILE C 1 312 ? 81.923  -29.888 24.523  1.00 48.68  ? 519 ILE C CD1  1 
ATOM   5330  N  N    . ARG C 1 313 ? 78.603  -33.880 21.986  1.00 46.62  ? 520 ARG C N    1 
ATOM   5331  C  CA   . ARG C 1 313 ? 78.367  -35.266 21.629  1.00 53.92  ? 520 ARG C CA   1 
ATOM   5332  C  C    . ARG C 1 313 ? 79.527  -36.132 22.096  1.00 55.58  ? 520 ARG C C    1 
ATOM   5333  O  O    . ARG C 1 313 ? 80.692  -35.833 21.796  1.00 57.67  ? 520 ARG C O    1 
ATOM   5334  C  CB   . ARG C 1 313 ? 78.183  -35.387 20.126  1.00 56.27  ? 520 ARG C CB   1 
ATOM   5335  C  CG   . ARG C 1 313 ? 77.220  -36.443 19.727  1.00 53.29  ? 520 ARG C CG   1 
ATOM   5336  C  CD   . ARG C 1 313 ? 77.296  -36.612 18.259  1.00 54.30  ? 520 ARG C CD   1 
ATOM   5337  N  NE   . ARG C 1 313 ? 76.652  -37.841 17.835  1.00 59.07  ? 520 ARG C NE   1 
ATOM   5338  C  CZ   . ARG C 1 313 ? 75.492  -37.881 17.191  1.00 56.57  ? 520 ARG C CZ   1 
ATOM   5339  N  NH1  . ARG C 1 313 ? 74.843  -36.749 16.921  1.00 50.37  ? 520 ARG C NH1  1 
ATOM   5340  N  NH2  . ARG C 1 313 ? 74.995  -39.047 16.815  1.00 54.73  ? 520 ARG C NH2  1 
ATOM   5341  N  N    . GLU C 1 314 ? 79.193  -37.208 22.823  1.00 53.51  ? 521 GLU C N    1 
ATOM   5342  C  CA   . GLU C 1 314 ? 80.192  -38.084 23.436  1.00 56.75  ? 521 GLU C CA   1 
ATOM   5343  C  C    . GLU C 1 314 ? 81.266  -38.482 22.438  1.00 57.44  ? 521 GLU C C    1 
ATOM   5344  O  O    . GLU C 1 314 ? 82.459  -38.465 22.757  1.00 65.39  ? 521 GLU C O    1 
ATOM   5345  C  CB   . GLU C 1 314 ? 79.498  -39.325 24.010  1.00 61.78  ? 521 GLU C CB   1 
ATOM   5346  C  CG   . GLU C 1 314 ? 80.344  -40.266 24.859  1.00 65.96  ? 521 GLU C CG   1 
ATOM   5347  C  CD   . GLU C 1 314 ? 79.489  -41.288 25.658  1.00 76.08  ? 521 GLU C CD   1 
ATOM   5348  O  OE1  . GLU C 1 314 ? 78.737  -42.104 25.051  1.00 65.92  ? 521 GLU C OE1  1 
ATOM   5349  O  OE2  . GLU C 1 314 ? 79.575  -41.273 26.907  1.00 79.31  ? 521 GLU C OE2  1 
ATOM   5350  N  N    . SER C 1 315 ? 80.865  -38.810 21.213  1.00 58.52  ? 522 SER C N    1 
ATOM   5351  C  CA   . SER C 1 315 ? 81.801  -39.242 20.184  1.00 55.74  ? 522 SER C CA   1 
ATOM   5352  C  C    . SER C 1 315 ? 82.628  -38.107 19.599  1.00 54.00  ? 522 SER C C    1 
ATOM   5353  O  O    . SER C 1 315 ? 83.560  -38.376 18.834  1.00 61.24  ? 522 SER C O    1 
ATOM   5354  C  CB   . SER C 1 315 ? 81.035  -39.950 19.056  1.00 58.48  ? 522 SER C CB   1 
ATOM   5355  O  OG   . SER C 1 315 ? 80.249  -39.041 18.279  1.00 61.69  ? 522 SER C OG   1 
ATOM   5356  N  N    . LYS C 1 316 ? 82.305  -36.851 19.910  1.00 59.14  ? 523 LYS C N    1 
ATOM   5357  C  CA   . LYS C 1 316 ? 83.014  -35.702 19.356  1.00 57.16  ? 523 LYS C CA   1 
ATOM   5358  C  C    . LYS C 1 316 ? 83.821  -34.958 20.404  1.00 56.84  ? 523 LYS C C    1 
ATOM   5359  O  O    . LYS C 1 316 ? 84.579  -34.038 20.055  1.00 55.02  ? 523 LYS C O    1 
ATOM   5360  C  CB   . LYS C 1 316 ? 82.020  -34.726 18.702  1.00 56.74  ? 523 LYS C CB   1 
ATOM   5361  C  CG   . LYS C 1 316 ? 81.238  -35.295 17.554  1.00 56.89  ? 523 LYS C CG   1 
ATOM   5362  C  CD   . LYS C 1 316 ? 82.146  -35.508 16.376  1.00 53.99  ? 523 LYS C CD   1 
ATOM   5363  C  CE   . LYS C 1 316 ? 81.680  -36.649 15.508  1.00 53.71  ? 523 LYS C CE   1 
ATOM   5364  N  NZ   . LYS C 1 316 ? 82.867  -37.260 14.824  1.00 66.98  ? 523 LYS C NZ   1 
ATOM   5365  N  N    . LEU C 1 317 ? 83.663  -35.334 21.673  1.00 51.75  ? 524 LEU C N    1 
ATOM   5366  C  CA   . LEU C 1 317 ? 84.296  -34.628 22.778  1.00 56.55  ? 524 LEU C CA   1 
ATOM   5367  C  C    . LEU C 1 317 ? 85.798  -34.437 22.549  1.00 60.51  ? 524 LEU C C    1 
ATOM   5368  O  O    . LEU C 1 317 ? 86.311  -33.313 22.644  1.00 62.63  ? 524 LEU C O    1 
ATOM   5369  C  CB   . LEU C 1 317 ? 84.010  -35.404 24.068  1.00 58.18  ? 524 LEU C CB   1 
ATOM   5370  C  CG   . LEU C 1 317 ? 83.979  -34.728 25.438  1.00 60.45  ? 524 LEU C CG   1 
ATOM   5371  C  CD1  . LEU C 1 317 ? 82.939  -33.648 25.539  1.00 52.67  ? 524 LEU C CD1  1 
ATOM   5372  C  CD2  . LEU C 1 317 ? 83.728  -35.796 26.493  1.00 63.80  ? 524 LEU C CD2  1 
ATOM   5373  N  N    . SER C 1 318 ? 86.520  -35.524 22.226  1.00 58.42  ? 525 SER C N    1 
ATOM   5374  C  CA   . SER C 1 318 ? 87.978  -35.432 22.083  1.00 64.42  ? 525 SER C CA   1 
ATOM   5375  C  C    . SER C 1 318 ? 88.374  -34.480 20.968  1.00 62.88  ? 525 SER C C    1 
ATOM   5376  O  O    . SER C 1 318 ? 89.330  -33.709 21.106  1.00 67.62  ? 525 SER C O    1 
ATOM   5377  C  CB   . SER C 1 318 ? 88.592  -36.812 21.838  1.00 62.94  ? 525 SER C CB   1 
ATOM   5378  O  OG   . SER C 1 318 ? 88.295  -37.682 22.920  1.00 68.59  ? 525 SER C OG   1 
ATOM   5379  N  N    . GLU C 1 319 ? 87.650  -34.501 19.860  1.00 58.17  ? 526 GLU C N    1 
ATOM   5380  C  CA   . GLU C 1 319 ? 87.961  -33.558 18.800  1.00 58.38  ? 526 GLU C CA   1 
ATOM   5381  C  C    . GLU C 1 319 ? 87.568  -32.130 19.192  1.00 60.68  ? 526 GLU C C    1 
ATOM   5382  O  O    . GLU C 1 319 ? 88.364  -31.198 19.047  1.00 61.77  ? 526 GLU C O    1 
ATOM   5383  C  CB   . GLU C 1 319 ? 87.270  -34.013 17.526  1.00 59.15  ? 526 GLU C CB   1 
ATOM   5384  C  CG   . GLU C 1 319 ? 87.716  -33.303 16.285  1.00 63.11  ? 526 GLU C CG   1 
ATOM   5385  C  CD   . GLU C 1 319 ? 86.907  -33.754 15.098  1.00 67.52  ? 526 GLU C CD   1 
ATOM   5386  O  OE1  . GLU C 1 319 ? 87.056  -33.145 14.014  1.00 70.57  ? 526 GLU C OE1  1 
ATOM   5387  O  OE2  . GLU C 1 319 ? 86.115  -34.719 15.270  1.00 59.30  ? 526 GLU C OE2  1 
ATOM   5388  N  N    . VAL C 1 320 ? 86.354  -31.942 19.720  1.00 57.33  ? 527 VAL C N    1 
ATOM   5389  C  CA   . VAL C 1 320 ? 85.893  -30.593 20.062  1.00 62.27  ? 527 VAL C CA   1 
ATOM   5390  C  C    . VAL C 1 320 ? 86.735  -29.991 21.184  1.00 60.09  ? 527 VAL C C    1 
ATOM   5391  O  O    . VAL C 1 320 ? 87.090  -28.805 21.144  1.00 57.31  ? 527 VAL C O    1 
ATOM   5392  C  CB   . VAL C 1 320 ? 84.400  -30.607 20.437  1.00 57.89  ? 527 VAL C CB   1 
ATOM   5393  C  CG1  . VAL C 1 320 ? 84.023  -29.338 21.208  1.00 55.35  ? 527 VAL C CG1  1 
ATOM   5394  C  CG2  . VAL C 1 320 ? 83.561  -30.733 19.196  1.00 60.05  ? 527 VAL C CG2  1 
ATOM   5395  N  N    . LEU C 1 321 ? 87.057  -30.788 22.207  1.00 60.18  ? 528 LEU C N    1 
ATOM   5396  C  CA   . LEU C 1 321 ? 87.872  -30.326 23.325  1.00 64.15  ? 528 LEU C CA   1 
ATOM   5397  C  C    . LEU C 1 321 ? 89.359  -30.653 23.149  1.00 62.84  ? 528 LEU C C    1 
ATOM   5398  O  O    . LEU C 1 321 ? 90.071  -30.858 24.139  1.00 62.00  ? 528 LEU C O    1 
ATOM   5399  C  CB   . LEU C 1 321 ? 87.328  -30.904 24.634  1.00 61.10  ? 528 LEU C CB   1 
ATOM   5400  C  CG   . LEU C 1 321 ? 85.888  -30.466 24.933  1.00 58.38  ? 528 LEU C CG   1 
ATOM   5401  C  CD1  . LEU C 1 321 ? 85.349  -31.051 26.232  1.00 55.62  ? 528 LEU C CD1  1 
ATOM   5402  C  CD2  . LEU C 1 321 ? 85.783  -28.942 24.955  1.00 53.10  ? 528 LEU C CD2  1 
ATOM   5403  N  N    . GLN C 1 322 ? 89.839  -30.713 21.910  1.00 64.26  ? 529 GLN C N    1 
ATOM   5404  C  CA   . GLN C 1 322 ? 91.255  -30.940 21.649  1.00 66.56  ? 529 GLN C CA   1 
ATOM   5405  C  C    . GLN C 1 322 ? 92.114  -29.921 22.394  1.00 71.48  ? 529 GLN C C    1 
ATOM   5406  O  O    . GLN C 1 322 ? 91.733  -28.758 22.544  1.00 73.99  ? 529 GLN C O    1 
ATOM   5407  C  CB   . GLN C 1 322 ? 91.511  -30.845 20.148  1.00 65.91  ? 529 GLN C CB   1 
ATOM   5408  C  CG   . GLN C 1 322 ? 91.363  -29.429 19.594  1.00 69.09  ? 529 GLN C CG   1 
ATOM   5409  C  CD   . GLN C 1 322 ? 91.223  -29.410 18.090  1.00 71.57  ? 529 GLN C CD   1 
ATOM   5410  O  OE1  . GLN C 1 322 ? 92.195  -29.163 17.362  1.00 75.28  ? 529 GLN C OE1  1 
ATOM   5411  N  NE2  . GLN C 1 322 ? 90.006  -29.657 17.610  1.00 65.55  ? 529 GLN C NE2  1 
ATOM   5412  N  N    . ALA C 1 323 ? 93.274  -30.354 22.879  1.00 68.51  ? 530 ALA C N    1 
ATOM   5413  C  CA   . ALA C 1 323 ? 94.158  -29.415 23.559  1.00 68.38  ? 530 ALA C CA   1 
ATOM   5414  C  C    . ALA C 1 323 ? 94.629  -28.334 22.597  1.00 66.21  ? 530 ALA C C    1 
ATOM   5415  O  O    . ALA C 1 323 ? 94.807  -28.569 21.400  1.00 76.02  ? 530 ALA C O    1 
ATOM   5416  C  CB   . ALA C 1 323 ? 95.362  -30.138 24.155  1.00 67.78  ? 530 ALA C CB   1 
ATOM   5417  N  N    . VAL C 1 324 ? 94.819  -27.131 23.124  1.00 69.60  ? 531 VAL C N    1 
ATOM   5418  C  CA   . VAL C 1 324 ? 95.267  -25.986 22.334  1.00 72.88  ? 531 VAL C CA   1 
ATOM   5419  C  C    . VAL C 1 324 ? 96.557  -25.458 22.954  1.00 73.96  ? 531 VAL C C    1 
ATOM   5420  O  O    . VAL C 1 324 ? 96.543  -24.921 24.069  1.00 79.55  ? 531 VAL C O    1 
ATOM   5421  C  CB   . VAL C 1 324 ? 94.199  -24.884 22.261  1.00 72.42  ? 531 VAL C CB   1 
ATOM   5422  C  CG1  . VAL C 1 324 ? 94.681  -23.721 21.383  1.00 74.13  ? 531 VAL C CG1  1 
ATOM   5423  C  CG2  . VAL C 1 324 ? 92.885  -25.445 21.727  1.00 66.49  ? 531 VAL C CG2  1 
ATOM   5424  N  N    . THR C 1 325 ? 97.647  -25.598 22.200  1.00 78.84  ? 532 THR C N    1 
ATOM   5425  C  CA   . THR C 1 325 ? 98.983  -25.145 22.659  1.00 82.83  ? 532 THR C CA   1 
ATOM   5426  C  C    . THR C 1 325 ? 99.425  -23.903 21.881  1.00 84.10  ? 532 THR C C    1 
ATOM   5427  O  O    . THR C 1 325 ? 98.680  -23.460 20.995  1.00 83.12  ? 532 THR C O    1 
ATOM   5428  C  CB   . THR C 1 325 ? 100.007 -26.266 22.463  1.00 81.23  ? 532 THR C CB   1 
ATOM   5429  O  OG1  . THR C 1 325 ? 100.069 -26.580 21.072  1.00 76.54  ? 532 THR C OG1  1 
ATOM   5430  C  CG2  . THR C 1 325 ? 99.670  -27.508 23.257  1.00 72.30  ? 532 THR C CG2  1 
ATOM   5431  N  N    . ASP C 1 326 ? 100.604 -23.371 22.203  1.00 84.76  ? 533 ASP C N    1 
ATOM   5432  C  CA   . ASP C 1 326 ? 101.082 -22.125 21.551  1.00 82.22  ? 533 ASP C CA   1 
ATOM   5433  C  C    . ASP C 1 326 ? 101.433 -22.411 20.091  1.00 82.87  ? 533 ASP C C    1 
ATOM   5434  O  O    . ASP C 1 326 ? 101.516 -21.449 19.320  1.00 81.47  ? 533 ASP C O    1 
ATOM   5435  C  CB   . ASP C 1 326 ? 102.235 -21.506 22.338  1.00 88.50  ? 533 ASP C CB   1 
ATOM   5436  C  CG   . ASP C 1 326 ? 102.112 -20.009 22.571  1.00 93.70  ? 533 ASP C CG   1 
ATOM   5437  O  OD1  . ASP C 1 326 ? 101.675 -19.298 21.649  1.00 89.29  ? 533 ASP C OD1  1 
ATOM   5438  O  OD2  . ASP C 1 326 ? 102.480 -19.562 23.672  1.00 91.74  ? 533 ASP C OD2  1 
ATOM   5439  N  N    . HIS C 1 327 ? 101.635 -23.679 19.730  1.00 87.57  ? 534 HIS C N    1 
ATOM   5440  C  CA   . HIS C 1 327 ? 101.893 -24.037 18.311  1.00 85.48  ? 534 HIS C CA   1 
ATOM   5441  C  C    . HIS C 1 327 ? 100.622 -23.786 17.508  1.00 87.04  ? 534 HIS C C    1 
ATOM   5442  O  O    . HIS C 1 327 ? 100.726 -23.440 16.323  1.00 85.85  ? 534 HIS C O    1 
ATOM   5443  C  CB   . HIS C 1 327 ? 102.342 -25.493 18.195  1.00 83.59  ? 534 HIS C CB   1 
ATOM   5444  C  CG   . HIS C 1 327 ? 103.332 -25.725 17.106  1.00 95.18  ? 534 HIS C CG   1 
ATOM   5445  N  ND1  . HIS C 1 327 ? 102.959 -25.838 15.783  1.00 98.47  ? 534 HIS C ND1  1 
ATOM   5446  C  CD2  . HIS C 1 327 ? 104.675 -25.858 17.135  1.00 92.54  ? 534 HIS C CD2  1 
ATOM   5447  C  CE1  . HIS C 1 327 ? 104.029 -26.033 15.042  1.00 92.73  ? 534 HIS C CE1  1 
ATOM   5448  N  NE2  . HIS C 1 327 ? 105.094 -26.050 15.848  1.00 95.66  ? 534 HIS C NE2  1 
ATOM   5449  N  N    . ASP C 1 328 ? 99.468  -23.937 18.152  1.00 90.45  ? 535 ASP C N    1 
ATOM   5450  C  CA   . ASP C 1 328 ? 98.172  -23.759 17.451  1.00 85.32  ? 535 ASP C CA   1 
ATOM   5451  C  C    . ASP C 1 328 ? 97.947  -22.265 17.232  1.00 85.65  ? 535 ASP C C    1 
ATOM   5452  O  O    . ASP C 1 328 ? 97.098  -21.918 16.401  1.00 91.57  ? 535 ASP C O    1 
ATOM   5453  C  CB   . ASP C 1 328 ? 97.046  -24.463 18.210  1.00 80.69  ? 535 ASP C CB   1 
ATOM   5454  C  CG   . ASP C 1 328 ? 97.277  -25.953 18.376  1.00 82.66  ? 535 ASP C CG   1 
ATOM   5455  O  OD1  . ASP C 1 328 ? 97.488  -26.626 17.354  1.00 87.31  ? 535 ASP C OD1  1 
ATOM   5456  O  OD2  . ASP C 1 328 ? 97.240  -26.426 19.520  1.00 82.92  ? 535 ASP C OD2  1 
ATOM   5457  N  N    . ILE C 1 329 ? 98.688  -21.420 17.943  1.00 86.20  ? 536 ILE C N    1 
ATOM   5458  C  CA   . ILE C 1 329 ? 98.585  -19.952 17.722  1.00 83.89  ? 536 ILE C CA   1 
ATOM   5459  C  C    . ILE C 1 329 ? 99.615  -19.558 16.670  1.00 82.38  ? 536 ILE C C    1 
ATOM   5460  O  O    . ILE C 1 329 ? 100.812 -19.742 16.915  1.00 87.96  ? 536 ILE C O    1 
ATOM   5461  C  CB   . ILE C 1 329 ? 98.769  -19.188 19.043  1.00 79.85  ? 536 ILE C CB   1 
ATOM   5462  C  CG1  . ILE C 1 329 ? 97.723  -19.622 20.069  1.00 84.26  ? 536 ILE C CG1  1 
ATOM   5463  C  CG2  . ILE C 1 329 ? 98.724  -17.690 18.812  1.00 78.36  ? 536 ILE C CG2  1 
ATOM   5464  C  CD1  . ILE C 1 329 ? 98.230  -19.732 21.475  1.00 75.31  ? 536 ILE C CD1  1 
ATOM   5465  N  N    . PRO C 1 330 ? 99.189  -19.028 15.510  1.00 79.90  ? 537 PRO C N    1 
ATOM   5466  C  CA   . PRO C 1 330 ? 100.125 -18.573 14.489  1.00 82.62  ? 537 PRO C CA   1 
ATOM   5467  C  C    . PRO C 1 330 ? 101.059 -17.451 14.974  1.00 85.06  ? 537 PRO C C    1 
ATOM   5468  O  O    . PRO C 1 330 ? 100.605 -16.551 15.648  1.00 81.22  ? 537 PRO C O    1 
ATOM   5469  C  CB   . PRO C 1 330 ? 99.195  -18.070 13.379  1.00 82.32  ? 537 PRO C CB   1 
ATOM   5470  C  CG   . PRO C 1 330 ? 97.902  -17.757 14.077  1.00 80.05  ? 537 PRO C CG   1 
ATOM   5471  C  CD   . PRO C 1 330 ? 97.794  -18.829 15.134  1.00 83.26  ? 537 PRO C CD   1 
ATOM   5472  N  N    . GLN C 1 331 ? 102.345 -17.535 14.615  1.00 84.82  ? 538 GLN C N    1 
ATOM   5473  C  CA   . GLN C 1 331 ? 103.316 -16.526 15.032  1.00 82.75  ? 538 GLN C CA   1 
ATOM   5474  C  C    . GLN C 1 331 ? 102.952 -15.135 14.522  1.00 81.53  ? 538 GLN C C    1 
ATOM   5475  O  O    . GLN C 1 331 ? 103.188 -14.141 15.221  1.00 78.37  ? 538 GLN C O    1 
ATOM   5476  N  N    . GLN C 1 332 ? 102.364 -15.039 13.321  1.00 80.40  ? 539 GLN C N    1 
ATOM   5477  C  CA   . GLN C 1 332 ? 101.984 -13.732 12.787  1.00 77.48  ? 539 GLN C CA   1 
ATOM   5478  C  C    . GLN C 1 332 ? 101.024 -13.005 13.722  1.00 79.55  ? 539 GLN C C    1 
ATOM   5479  O  O    . GLN C 1 332 ? 100.941 -11.771 13.699  1.00 73.43  ? 539 GLN C O    1 
ATOM   5480  N  N    . LEU C 1 333 ? 100.304 -13.756 14.556  1.00 81.64  ? 540 LEU C N    1 
ATOM   5481  C  CA   . LEU C 1 333 ? 99.329  -13.192 15.476  1.00 79.23  ? 540 LEU C CA   1 
ATOM   5482  C  C    . LEU C 1 333 ? 99.965  -12.759 16.789  1.00 77.38  ? 540 LEU C C    1 
ATOM   5483  O  O    . LEU C 1 333 ? 99.681  -11.667 17.290  1.00 70.45  ? 540 LEU C O    1 
ATOM   5484  C  CB   . LEU C 1 333 ? 98.223  -14.203 15.753  1.00 71.65  ? 540 LEU C CB   1 
ATOM   5485  C  CG   . LEU C 1 333 ? 97.186  -13.660 16.733  1.00 70.26  ? 540 LEU C CG   1 
ATOM   5486  C  CD1  . LEU C 1 333 ? 96.051  -12.932 16.009  1.00 71.72  ? 540 LEU C CD1  1 
ATOM   5487  C  CD2  . LEU C 1 333 ? 96.671  -14.781 17.604  1.00 68.04  ? 540 LEU C CD2  1 
ATOM   5488  N  N    . VAL C 1 334 ? 100.805 -13.615 17.374  1.00 78.93  ? 541 VAL C N    1 
ATOM   5489  C  CA   . VAL C 1 334 ? 101.575 -13.191 18.538  1.00 79.80  ? 541 VAL C CA   1 
ATOM   5490  C  C    . VAL C 1 334 ? 102.316 -11.900 18.219  1.00 77.83  ? 541 VAL C C    1 
ATOM   5491  O  O    . VAL C 1 334 ? 102.341 -10.963 19.026  1.00 78.58  ? 541 VAL C O    1 
ATOM   5492  C  CB   . VAL C 1 334 ? 102.533 -14.312 18.987  1.00 84.23  ? 541 VAL C CB   1 
ATOM   5493  C  CG1  . VAL C 1 334 ? 103.451 -13.817 20.101  1.00 79.30  ? 541 VAL C CG1  1 
ATOM   5494  C  CG2  . VAL C 1 334 ? 101.754 -15.540 19.433  1.00 75.25  ? 541 VAL C CG2  1 
ATOM   5495  N  N    . GLU C 1 335 ? 102.882 -11.810 17.010  1.00 76.46  ? 542 GLU C N    1 
ATOM   5496  C  CA   . GLU C 1 335 ? 103.517 -10.569 16.581  1.00 72.76  ? 542 GLU C CA   1 
ATOM   5497  C  C    . GLU C 1 335 ? 102.508 -9.431  16.504  1.00 78.87  ? 542 GLU C C    1 
ATOM   5498  O  O    . GLU C 1 335 ? 102.820 -8.288  16.870  1.00 81.40  ? 542 GLU C O    1 
ATOM   5499  N  N    . ARG C 1 336 ? 101.290 -9.719  16.034  1.00 79.32  ? 543 ARG C N    1 
ATOM   5500  C  CA   . ARG C 1 336 ? 100.277 -8.670  15.925  1.00 74.94  ? 543 ARG C CA   1 
ATOM   5501  C  C    . ARG C 1 336 ? 99.885  -8.138  17.304  1.00 77.53  ? 543 ARG C C    1 
ATOM   5502  O  O    . ARG C 1 336 ? 99.810  -6.923  17.513  1.00 75.55  ? 543 ARG C O    1 
ATOM   5503  C  CB   . ARG C 1 336 ? 99.057  -9.197  15.168  1.00 74.19  ? 543 ARG C CB   1 
ATOM   5504  N  N    . LEU C 1 337 ? 99.655  -9.038  18.268  1.00 77.08  ? 544 LEU C N    1 
ATOM   5505  C  CA   . LEU C 1 337 ? 99.309  -8.609  19.622  1.00 78.21  ? 544 LEU C CA   1 
ATOM   5506  C  C    . LEU C 1 337 ? 100.481 -7.885  20.289  1.00 79.46  ? 544 LEU C C    1 
ATOM   5507  O  O    . LEU C 1 337 ? 100.329 -6.761  20.787  1.00 72.16  ? 544 LEU C O    1 
ATOM   5508  N  N    . GLN C 1 338 ? 101.659 -8.520  20.311  1.00 78.50  ? 545 GLN C N    1 
ATOM   5509  C  CA   . GLN C 1 338 ? 102.850 -7.873  20.861  1.00 75.01  ? 545 GLN C CA   1 
ATOM   5510  C  C    . GLN C 1 338 ? 103.054 -6.494  20.243  1.00 74.01  ? 545 GLN C C    1 
ATOM   5511  O  O    . GLN C 1 338 ? 103.256 -5.507  20.959  1.00 74.68  ? 545 GLN C O    1 
ATOM   5512  C  CB   . GLN C 1 338 ? 104.077 -8.750  20.633  1.00 68.19  ? 545 GLN C CB   1 
ATOM   5513  C  CG   . GLN C 1 338 ? 104.482 -9.596  21.816  1.00 69.39  ? 545 GLN C CG   1 
ATOM   5514  C  CD   . GLN C 1 338 ? 105.419 -10.734 21.416  1.00 74.42  ? 545 GLN C CD   1 
ATOM   5515  O  OE1  . GLN C 1 338 ? 105.719 -10.916 20.230  1.00 70.64  ? 545 GLN C OE1  1 
ATOM   5516  N  NE2  . GLN C 1 338 ? 105.879 -11.508 22.401  1.00 68.21  ? 545 GLN C NE2  1 
ATOM   5517  N  N    . GLU C 1 339 ? 102.951 -6.402  18.910  1.00 74.61  ? 546 GLU C N    1 
ATOM   5518  C  CA   . GLU C 1 339 ? 103.051 -5.113  18.227  1.00 75.94  ? 546 GLU C CA   1 
ATOM   5519  C  C    . GLU C 1 339 ? 101.954 -4.143  18.648  1.00 75.21  ? 546 GLU C C    1 
ATOM   5520  O  O    . GLU C 1 339 ? 102.099 -2.934  18.444  1.00 75.51  ? 546 GLU C O    1 
ATOM   5521  N  N    . GLU C 1 340 ? 100.891 -4.636  19.273  1.00 78.38  ? 547 GLU C N    1 
ATOM   5522  C  CA   . GLU C 1 340 ? 99.756  -3.756  19.650  1.00 72.13  ? 547 GLU C CA   1 
ATOM   5523  C  C    . GLU C 1 340 ? 99.903  -3.323  21.106  1.00 75.63  ? 547 GLU C C    1 
ATOM   5524  O  O    . GLU C 1 340 ? 99.583  -2.165  21.400  1.00 78.74  ? 547 GLU C O    1 
ATOM   5525  N  N    . LYS C 1 341 ? 100.423 -4.196  21.964  1.00 73.76  ? 548 LYS C N    1 
ATOM   5526  C  CA   . LYS C 1 341 ? 100.509 -3.898  23.416  1.00 73.06  ? 548 LYS C CA   1 
ATOM   5527  C  C    . LYS C 1 341 ? 101.465 -2.733  23.679  1.00 81.95  ? 548 LYS C C    1 
ATOM   5528  O  O    . LYS C 1 341 ? 101.512 -2.298  24.838  1.00 84.48  ? 548 LYS C O    1 
ATOM   5529  C  CB   . LYS C 1 341 ? 100.907 -5.160  24.182  1.00 69.92  ? 548 LYS C CB   1 
ATOM   5530  N  N    . ARG C 1 342 ? 102.229 -2.285  22.682  1.00 81.81  ? 549 ARG C N    1 
ATOM   5531  C  CA   . ARG C 1 342 ? 103.062 -1.068  22.836  1.00 79.20  ? 549 ARG C CA   1 
ATOM   5532  C  C    . ARG C 1 342 ? 102.110 0.093   23.119  1.00 87.79  ? 549 ARG C C    1 
ATOM   5533  O  O    . ARG C 1 342 ? 101.628 0.722   22.150  1.00 85.92  ? 549 ARG C O    1 
ATOM   5534  C  CB   . ARG C 1 342 ? 103.887 -0.821  21.574  1.00 73.32  ? 549 ARG C CB   1 
ATOM   5535  N  N    . ILE C 1 343 ? 101.812 0.326   24.397  1.00 86.03  ? 550 ILE C N    1 
ATOM   5536  C  CA   . ILE C 1 343 ? 100.883 1.414   24.794  1.00 84.77  ? 550 ILE C CA   1 
ATOM   5537  C  C    . ILE C 1 343 ? 101.717 2.463   25.517  1.00 95.35  ? 550 ILE C C    1 
ATOM   5538  O  O    . ILE C 1 343 ? 102.552 2.086   26.359  1.00 90.26  ? 550 ILE C O    1 
ATOM   5539  C  CB   . ILE C 1 343 ? 99.742  0.882   25.675  1.00 85.66  ? 550 ILE C CB   1 
ATOM   5540  C  CG1  . ILE C 1 343 ? 98.869  -0.136  24.936  1.00 84.51  ? 550 ILE C CG1  1 
ATOM   5541  C  CG2  . ILE C 1 343 ? 98.915  2.030   26.227  1.00 87.13  ? 550 ILE C CG2  1 
ATOM   5542  C  CD1  . ILE C 1 343 ? 98.240  0.388   23.666  1.00 85.68  ? 550 ILE C CD1  1 
ATOM   5543  N  N    . GLU C 1 344 ? 101.490 3.730   25.194  1.00 94.51  ? 551 GLU C N    1 
ATOM   5544  C  CA   . GLU C 1 344 ? 102.272 4.812   25.779  1.00 93.54  ? 551 GLU C CA   1 
ATOM   5545  C  C    . GLU C 1 344 ? 101.371 5.881   26.395  1.00 96.50  ? 551 GLU C C    1 
ATOM   5546  O  O    . GLU C 1 344 ? 100.146 5.892   26.213  1.00 87.39  ? 551 GLU C O    1 
ATOM   5547  C  CB   . GLU C 1 344 ? 103.199 5.449   24.731  1.00 86.88  ? 551 GLU C CB   1 
ATOM   5548  N  N    . ALA C 1 345 ? 102.009 6.783   27.146  1.00 95.90  ? 552 ALA C N    1 
ATOM   5549  C  CA   . ALA C 1 345 ? 101.364 7.978   27.689  1.00 93.77  ? 552 ALA C CA   1 
ATOM   5550  C  C    . ALA C 1 345 ? 102.313 9.178   27.591  1.00 90.40  ? 552 ALA C C    1 
ATOM   5551  O  O    . ALA C 1 345 ? 102.775 9.540   26.502  1.00 81.00  ? 552 ALA C O    1 
ATOM   5552  C  CB   . ALA C 1 345 ? 100.925 7.750   29.137  1.00 89.43  ? 552 ALA C CB   1 
ATOM   5553  N  N    . MET D 2 1   ? 52.381  -15.672 0.889   1.00 48.33  ? 1   MET D N    1 
ATOM   5554  C  CA   . MET D 2 1   ? 52.763  -17.016 1.295   1.00 55.22  ? 1   MET D CA   1 
ATOM   5555  C  C    . MET D 2 1   ? 52.580  -17.198 2.799   1.00 55.31  ? 1   MET D C    1 
ATOM   5556  O  O    . MET D 2 1   ? 52.819  -16.275 3.580   1.00 58.38  ? 1   MET D O    1 
ATOM   5557  C  CB   . MET D 2 1   ? 54.217  -17.295 0.900   1.00 52.01  ? 1   MET D CB   1 
ATOM   5558  C  CG   . MET D 2 1   ? 55.191  -16.282 1.491   1.00 53.54  ? 1   MET D CG   1 
ATOM   5559  S  SD   . MET D 2 1   ? 56.903  -16.604 1.121   1.00 64.63  ? 1   MET D SD   1 
ATOM   5560  C  CE   . MET D 2 1   ? 57.716  -15.239 1.928   1.00 52.36  ? 1   MET D CE   1 
ATOM   5561  N  N    . GLN D 2 2   ? 52.177  -18.399 3.196   1.00 53.72  ? 2   GLN D N    1 
ATOM   5562  C  CA   . GLN D 2 2   ? 51.939  -18.735 4.593   1.00 56.27  ? 2   GLN D CA   1 
ATOM   5563  C  C    . GLN D 2 2   ? 53.183  -19.397 5.196   1.00 52.21  ? 2   GLN D C    1 
ATOM   5564  O  O    . GLN D 2 2   ? 53.528  -20.532 4.847   1.00 47.40  ? 2   GLN D O    1 
ATOM   5565  C  CB   . GLN D 2 2   ? 50.727  -19.647 4.721   1.00 43.73  ? 2   GLN D CB   1 
ATOM   5566  C  CG   . GLN D 2 2   ? 50.561  -20.157 6.115   1.00 42.54  ? 2   GLN D CG   1 
ATOM   5567  C  CD   . GLN D 2 2   ? 49.461  -21.184 6.234   1.00 55.34  ? 2   GLN D CD   1 
ATOM   5568  O  OE1  . GLN D 2 2   ? 49.688  -22.387 6.050   1.00 55.84  ? 2   GLN D OE1  1 
ATOM   5569  N  NE2  . GLN D 2 2   ? 48.249  -20.717 6.536   1.00 55.42  ? 2   GLN D NE2  1 
ATOM   5570  N  N    . ILE D 2 3   ? 53.826  -18.695 6.126   1.00 50.15  ? 3   ILE D N    1 
ATOM   5571  C  CA   . ILE D 2 3   ? 54.943  -19.213 6.902   1.00 45.59  ? 3   ILE D CA   1 
ATOM   5572  C  C    . ILE D 2 3   ? 54.440  -19.696 8.257   1.00 52.28  ? 3   ILE D C    1 
ATOM   5573  O  O    . ILE D 2 3   ? 53.256  -19.545 8.585   1.00 53.00  ? 3   ILE D O    1 
ATOM   5574  C  CB   . ILE D 2 3   ? 56.023  -18.142 7.080   1.00 48.31  ? 3   ILE D CB   1 
ATOM   5575  C  CG1  . ILE D 2 3   ? 55.540  -17.052 8.043   1.00 49.71  ? 3   ILE D CG1  1 
ATOM   5576  C  CG2  . ILE D 2 3   ? 56.379  -17.543 5.746   1.00 53.21  ? 3   ILE D CG2  1 
ATOM   5577  C  CD1  . ILE D 2 3   ? 56.676  -16.165 8.540   1.00 49.81  ? 3   ILE D CD1  1 
ATOM   5578  N  N    . PHE D 2 4   ? 55.330  -20.292 9.044   1.00 46.34  ? 4   PHE D N    1 
ATOM   5579  C  CA   . PHE D 2 4   ? 55.044  -20.688 10.410  1.00 46.49  ? 4   PHE D CA   1 
ATOM   5580  C  C    . PHE D 2 4   ? 55.902  -19.887 11.376  1.00 45.89  ? 4   PHE D C    1 
ATOM   5581  O  O    . PHE D 2 4   ? 56.977  -19.401 11.026  1.00 43.81  ? 4   PHE D O    1 
ATOM   5582  C  CB   . PHE D 2 4   ? 55.301  -22.175 10.621  1.00 48.94  ? 4   PHE D CB   1 
ATOM   5583  C  CG   . PHE D 2 4   ? 54.553  -23.053 9.671   1.00 54.09  ? 4   PHE D CG   1 
ATOM   5584  C  CD1  . PHE D 2 4   ? 53.185  -23.230 9.802   1.00 56.44  ? 4   PHE D CD1  1 
ATOM   5585  C  CD2  . PHE D 2 4   ? 55.213  -23.700 8.642   1.00 56.67  ? 4   PHE D CD2  1 
ATOM   5586  C  CE1  . PHE D 2 4   ? 52.488  -24.031 8.921   1.00 57.93  ? 4   PHE D CE1  1 
ATOM   5587  C  CE2  . PHE D 2 4   ? 54.522  -24.507 7.757   1.00 56.94  ? 4   PHE D CE2  1 
ATOM   5588  C  CZ   . PHE D 2 4   ? 53.161  -24.673 7.893   1.00 58.14  ? 4   PHE D CZ   1 
ATOM   5589  N  N    . VAL D 2 5   ? 55.402  -19.739 12.596  1.00 46.82  ? 5   VAL D N    1 
ATOM   5590  C  CA   . VAL D 2 5   ? 56.135  -19.081 13.665  1.00 45.94  ? 5   VAL D CA   1 
ATOM   5591  C  C    . VAL D 2 5   ? 55.916  -19.916 14.911  1.00 49.74  ? 5   VAL D C    1 
ATOM   5592  O  O    . VAL D 2 5   ? 54.775  -20.051 15.363  1.00 53.83  ? 5   VAL D O    1 
ATOM   5593  C  CB   . VAL D 2 5   ? 55.656  -17.638 13.918  1.00 44.00  ? 5   VAL D CB   1 
ATOM   5594  C  CG1  . VAL D 2 5   ? 56.274  -17.122 15.215  1.00 47.61  ? 5   VAL D CG1  1 
ATOM   5595  C  CG2  . VAL D 2 5   ? 56.004  -16.712 12.783  1.00 34.58  ? 5   VAL D CG2  1 
ATOM   5596  N  N    . LYS D 2 6   ? 56.982  -20.480 15.471  1.00 50.13  ? 6   LYS D N    1 
ATOM   5597  C  CA   . LYS D 2 6   ? 56.835  -21.211 16.730  1.00 55.93  ? 6   LYS D CA   1 
ATOM   5598  C  C    . LYS D 2 6   ? 56.888  -20.220 17.891  1.00 52.33  ? 6   LYS D C    1 
ATOM   5599  O  O    . LYS D 2 6   ? 57.922  -19.578 18.113  1.00 50.48  ? 6   LYS D O    1 
ATOM   5600  C  CB   . LYS D 2 6   ? 57.907  -22.298 16.865  1.00 57.28  ? 6   LYS D CB   1 
ATOM   5601  C  CG   . LYS D 2 6   ? 57.346  -23.692 17.250  1.00 55.74  ? 6   LYS D CG   1 
ATOM   5602  C  CD   . LYS D 2 6   ? 58.291  -24.811 16.827  1.00 63.35  ? 6   LYS D CD   1 
ATOM   5603  N  N    . THR D 2 7   ? 55.781  -20.100 18.634  1.00 52.47  ? 7   THR D N    1 
ATOM   5604  C  CA   . THR D 2 7   ? 55.630  -19.030 19.621  1.00 54.59  ? 7   THR D CA   1 
ATOM   5605  C  C    . THR D 2 7   ? 56.280  -19.391 20.956  1.00 59.66  ? 7   THR D C    1 
ATOM   5606  O  O    . THR D 2 7   ? 56.903  -20.446 21.118  1.00 61.64  ? 7   THR D O    1 
ATOM   5607  C  CB   . THR D 2 7   ? 54.162  -18.703 19.886  1.00 54.20  ? 7   THR D CB   1 
ATOM   5608  O  OG1  . THR D 2 7   ? 53.580  -19.744 20.676  1.00 54.80  ? 7   THR D OG1  1 
ATOM   5609  C  CG2  . THR D 2 7   ? 53.376  -18.509 18.594  1.00 55.11  ? 7   THR D CG2  1 
ATOM   5610  N  N    . LEU D 2 8   ? 56.106  -18.499 21.939  1.00 57.16  ? 8   LEU D N    1 
ATOM   5611  C  CA   . LEU D 2 8   ? 56.687  -18.729 23.260  1.00 61.01  ? 8   LEU D CA   1 
ATOM   5612  C  C    . LEU D 2 8   ? 56.107  -19.981 23.903  1.00 61.39  ? 8   LEU D C    1 
ATOM   5613  O  O    . LEU D 2 8   ? 56.844  -20.763 24.510  1.00 65.61  ? 8   LEU D O    1 
ATOM   5614  C  CB   . LEU D 2 8   ? 56.479  -17.506 24.152  1.00 56.75  ? 8   LEU D CB   1 
ATOM   5615  C  CG   . LEU D 2 8   ? 56.975  -16.221 23.484  1.00 59.01  ? 8   LEU D CG   1 
ATOM   5616  C  CD1  . LEU D 2 8   ? 56.686  -14.979 24.330  1.00 65.04  ? 8   LEU D CD1  1 
ATOM   5617  C  CD2  . LEU D 2 8   ? 58.463  -16.314 23.119  1.00 54.66  ? 8   LEU D CD2  1 
ATOM   5618  N  N    . THR D 2 9   ? 54.794  -20.201 23.752  1.00 60.15  ? 9   THR D N    1 
ATOM   5619  C  CA   . THR D 2 9   ? 54.169  -21.444 24.199  1.00 60.81  ? 9   THR D CA   1 
ATOM   5620  C  C    . THR D 2 9   ? 54.838  -22.678 23.606  1.00 67.80  ? 9   THR D C    1 
ATOM   5621  O  O    . THR D 2 9   ? 54.789  -23.749 24.215  1.00 62.56  ? 9   THR D O    1 
ATOM   5622  C  CB   . THR D 2 9   ? 52.683  -21.462 23.819  1.00 66.63  ? 9   THR D CB   1 
ATOM   5623  O  OG1  . THR D 2 9   ? 52.537  -21.261 22.400  1.00 71.38  ? 9   THR D OG1  1 
ATOM   5624  C  CG2  . THR D 2 9   ? 51.933  -20.361 24.546  1.00 65.18  ? 9   THR D CG2  1 
ATOM   5625  N  N    . GLY D 2 10  ? 55.477  -22.553 22.435  1.00 69.65  ? 10  GLY D N    1 
ATOM   5626  C  CA   . GLY D 2 10  ? 55.921  -23.699 21.668  1.00 56.44  ? 10  GLY D CA   1 
ATOM   5627  C  C    . GLY D 2 10  ? 54.955  -24.119 20.587  1.00 55.70  ? 10  GLY D C    1 
ATOM   5628  O  O    . GLY D 2 10  ? 55.305  -24.960 19.755  1.00 56.36  ? 10  GLY D O    1 
ATOM   5629  N  N    . LYS D 2 11  ? 53.752  -23.557 20.570  1.00 59.06  ? 11  LYS D N    1 
ATOM   5630  C  CA   . LYS D 2 11  ? 52.803  -23.867 19.518  1.00 59.83  ? 11  LYS D CA   1 
ATOM   5631  C  C    . LYS D 2 11  ? 53.183  -23.146 18.230  1.00 61.13  ? 11  LYS D C    1 
ATOM   5632  O  O    . LYS D 2 11  ? 53.790  -22.064 18.246  1.00 60.16  ? 11  LYS D O    1 
ATOM   5633  C  CB   . LYS D 2 11  ? 51.384  -23.471 19.940  1.00 57.72  ? 11  LYS D CB   1 
ATOM   5634  N  N    . THR D 2 12  ? 52.825  -23.767 17.104  1.00 55.58  ? 12  THR D N    1 
ATOM   5635  C  CA   . THR D 2 12  ? 52.997  -23.164 15.792  1.00 58.48  ? 12  THR D CA   1 
ATOM   5636  C  C    . THR D 2 12  ? 51.743  -22.389 15.407  1.00 52.93  ? 12  THR D C    1 
ATOM   5637  O  O    . THR D 2 12  ? 50.633  -22.922 15.484  1.00 56.93  ? 12  THR D O    1 
ATOM   5638  C  CB   . THR D 2 12  ? 53.276  -24.232 14.734  1.00 61.02  ? 12  THR D CB   1 
ATOM   5639  O  OG1  . THR D 2 12  ? 54.420  -25.003 15.114  1.00 67.56  ? 12  THR D OG1  1 
ATOM   5640  C  CG2  . THR D 2 12  ? 53.547  -23.583 13.387  1.00 56.47  ? 12  THR D CG2  1 
ATOM   5641  N  N    . ILE D 2 13  ? 51.923  -21.141 14.991  1.00 48.09  ? 13  ILE D N    1 
ATOM   5642  C  CA   . ILE D 2 13  ? 50.855  -20.372 14.373  1.00 55.55  ? 13  ILE D CA   1 
ATOM   5643  C  C    . ILE D 2 13  ? 51.228  -20.116 12.921  1.00 54.07  ? 13  ILE D C    1 
ATOM   5644  O  O    . ILE D 2 13  ? 52.366  -20.332 12.494  1.00 53.52  ? 13  ILE D O    1 
ATOM   5645  C  CB   . ILE D 2 13  ? 50.557  -19.049 15.110  1.00 48.59  ? 13  ILE D CB   1 
ATOM   5646  C  CG1  . ILE D 2 13  ? 51.842  -18.253 15.309  1.00 47.53  ? 13  ILE D CG1  1 
ATOM   5647  C  CG2  . ILE D 2 13  ? 49.798  -19.330 16.419  1.00 49.06  ? 13  ILE D CG2  1 
ATOM   5648  C  CD1  . ILE D 2 13  ? 51.650  -16.748 15.390  1.00 49.05  ? 13  ILE D CD1  1 
ATOM   5649  N  N    . THR D 2 14  ? 50.242  -19.674 12.154  1.00 48.05  ? 14  THR D N    1 
ATOM   5650  C  CA   . THR D 2 14  ? 50.454  -19.325 10.761  1.00 52.00  ? 14  THR D CA   1 
ATOM   5651  C  C    . THR D 2 14  ? 50.538  -17.812 10.628  1.00 51.99  ? 14  THR D C    1 
ATOM   5652  O  O    . THR D 2 14  ? 50.127  -17.054 11.508  1.00 50.29  ? 14  THR D O    1 
ATOM   5653  C  CB   . THR D 2 14  ? 49.337  -19.883 9.871   1.00 52.15  ? 14  THR D CB   1 
ATOM   5654  O  OG1  . THR D 2 14  ? 48.082  -19.316 10.264  1.00 54.50  ? 14  THR D OG1  1 
ATOM   5655  C  CG2  . THR D 2 14  ? 49.248  -21.405 10.021  1.00 58.06  ? 14  THR D CG2  1 
ATOM   5656  N  N    . LEU D 2 15  ? 51.087  -17.384 9.505   1.00 48.02  ? 15  LEU D N    1 
ATOM   5657  C  CA   . LEU D 2 15  ? 51.299  -15.971 9.250   1.00 51.36  ? 15  LEU D CA   1 
ATOM   5658  C  C    . LEU D 2 15  ? 51.303  -15.809 7.739   1.00 57.47  ? 15  LEU D C    1 
ATOM   5659  O  O    . LEU D 2 15  ? 52.216  -16.301 7.064   1.00 57.35  ? 15  LEU D O    1 
ATOM   5660  C  CB   . LEU D 2 15  ? 52.608  -15.492 9.867   1.00 49.85  ? 15  LEU D CB   1 
ATOM   5661  C  CG   . LEU D 2 15  ? 52.659  -14.108 10.497  1.00 47.23  ? 15  LEU D CG   1 
ATOM   5662  C  CD1  . LEU D 2 15  ? 51.885  -14.108 11.803  1.00 56.88  ? 15  LEU D CD1  1 
ATOM   5663  C  CD2  . LEU D 2 15  ? 54.098  -13.707 10.736  1.00 49.92  ? 15  LEU D CD2  1 
ATOM   5664  N  N    . GLU D 2 16  ? 50.264  -15.168 7.213   1.00 57.64  ? 16  GLU D N    1 
ATOM   5665  C  CA   . GLU D 2 16  ? 50.250  -14.754 5.816   1.00 58.86  ? 16  GLU D CA   1 
ATOM   5666  C  C    . GLU D 2 16  ? 51.233  -13.593 5.637   1.00 56.24  ? 16  GLU D C    1 
ATOM   5667  O  O    . GLU D 2 16  ? 51.031  -12.516 6.201   1.00 57.48  ? 16  GLU D O    1 
ATOM   5668  C  CB   . GLU D 2 16  ? 48.825  -14.371 5.425   1.00 56.81  ? 16  GLU D CB   1 
ATOM   5669  C  CG   . GLU D 2 16  ? 48.677  -13.880 4.007   1.00 64.19  ? 16  GLU D CG   1 
ATOM   5670  C  CD   . GLU D 2 16  ? 49.375  -14.779 2.999   1.00 64.25  ? 16  GLU D CD   1 
ATOM   5671  O  OE1  . GLU D 2 16  ? 49.144  -16.010 3.065   1.00 63.84  ? 16  GLU D OE1  1 
ATOM   5672  O  OE2  . GLU D 2 16  ? 50.157  -14.254 2.163   1.00 61.33  ? 16  GLU D OE2  1 
ATOM   5673  N  N    . VAL D 2 17  ? 52.333  -13.809 4.905   1.00 53.20  ? 17  VAL D N    1 
ATOM   5674  C  CA   . VAL D 2 17  ? 53.330  -12.770 4.670   1.00 49.88  ? 17  VAL D CA   1 
ATOM   5675  C  C    . VAL D 2 17  ? 53.701  -12.772 3.192   1.00 58.17  ? 17  VAL D C    1 
ATOM   5676  O  O    . VAL D 2 17  ? 53.238  -13.611 2.415   1.00 53.14  ? 17  VAL D O    1 
ATOM   5677  C  CB   . VAL D 2 17  ? 54.602  -12.945 5.523   1.00 53.11  ? 17  VAL D CB   1 
ATOM   5678  C  CG1  . VAL D 2 17  ? 54.316  -12.913 7.040   1.00 53.78  ? 17  VAL D CG1  1 
ATOM   5679  C  CG2  . VAL D 2 17  ? 55.328  -14.215 5.100   1.00 59.82  ? 17  VAL D CG2  1 
ATOM   5680  N  N    . GLU D 2 18  ? 54.581  -11.837 2.821   1.00 52.73  ? 18  GLU D N    1 
ATOM   5681  C  CA   . GLU D 2 18  ? 55.076  -11.719 1.459   1.00 56.69  ? 18  GLU D CA   1 
ATOM   5682  C  C    . GLU D 2 18  ? 56.596  -11.695 1.466   1.00 59.15  ? 18  GLU D C    1 
ATOM   5683  O  O    . GLU D 2 18  ? 57.206  -11.240 2.441   1.00 61.03  ? 18  GLU D O    1 
ATOM   5684  C  CB   . GLU D 2 18  ? 54.539  -10.451 0.762   1.00 51.76  ? 18  GLU D CB   1 
ATOM   5685  C  CG   . GLU D 2 18  ? 53.001  -10.482 0.520   1.00 54.34  ? 18  GLU D CG   1 
ATOM   5686  C  CD   . GLU D 2 18  ? 52.516  -11.747 -0.196  1.00 62.86  ? 18  GLU D CD   1 
ATOM   5687  O  OE1  . GLU D 2 18  ? 53.190  -12.178 -1.174  1.00 57.12  ? 18  GLU D OE1  1 
ATOM   5688  O  OE2  . GLU D 2 18  ? 51.460  -12.312 0.227   1.00 63.87  ? 18  GLU D OE2  1 
ATOM   5689  N  N    . PRO D 2 19  ? 57.234  -12.169 0.388   1.00 57.58  ? 19  PRO D N    1 
ATOM   5690  C  CA   . PRO D 2 19  ? 58.705  -12.209 0.359   1.00 57.76  ? 19  PRO D CA   1 
ATOM   5691  C  C    . PRO D 2 19  ? 59.363  -10.865 0.559   1.00 61.17  ? 19  PRO D C    1 
ATOM   5692  O  O    . PRO D 2 19  ? 60.537  -10.829 0.943   1.00 61.28  ? 19  PRO D O    1 
ATOM   5693  C  CB   . PRO D 2 19  ? 59.013  -12.760 -1.038  1.00 57.27  ? 19  PRO D CB   1 
ATOM   5694  C  CG   . PRO D 2 19  ? 57.768  -13.485 -1.435  1.00 52.89  ? 19  PRO D CG   1 
ATOM   5695  C  CD   . PRO D 2 19  ? 56.652  -12.701 -0.857  1.00 53.51  ? 19  PRO D CD   1 
ATOM   5696  N  N    . SER D 2 20  ? 58.660  -9.761  0.304   1.00 62.56  ? 20  SER D N    1 
ATOM   5697  C  CA   . SER D 2 20  ? 59.248  -8.427  0.368   1.00 65.72  ? 20  SER D CA   1 
ATOM   5698  C  C    . SER D 2 20  ? 58.973  -7.724  1.693   1.00 66.87  ? 20  SER D C    1 
ATOM   5699  O  O    . SER D 2 20  ? 59.479  -6.617  1.902   1.00 67.93  ? 20  SER D O    1 
ATOM   5700  C  CB   . SER D 2 20  ? 58.741  -7.565  -0.808  1.00 62.43  ? 20  SER D CB   1 
ATOM   5701  O  OG   . SER D 2 20  ? 57.352  -7.261  -0.681  1.00 53.39  ? 20  SER D OG   1 
ATOM   5702  N  N    . ASP D 2 21  ? 58.187  -8.332  2.587   1.00 62.97  ? 21  ASP D N    1 
ATOM   5703  C  CA   . ASP D 2 21  ? 58.003  -7.773  3.920   1.00 61.37  ? 21  ASP D CA   1 
ATOM   5704  C  C    . ASP D 2 21  ? 59.340  -7.592  4.622   1.00 69.33  ? 21  ASP D C    1 
ATOM   5705  O  O    . ASP D 2 21  ? 60.221  -8.461  4.550   1.00 64.03  ? 21  ASP D O    1 
ATOM   5706  C  CB   . ASP D 2 21  ? 57.116  -8.681  4.764   1.00 55.70  ? 21  ASP D CB   1 
ATOM   5707  C  CG   . ASP D 2 21  ? 55.682  -8.641  4.333   1.00 61.53  ? 21  ASP D CG   1 
ATOM   5708  O  OD1  . ASP D 2 21  ? 55.299  -7.647  3.681   1.00 74.11  ? 21  ASP D OD1  1 
ATOM   5709  O  OD2  . ASP D 2 21  ? 54.932  -9.594  4.629   1.00 59.83  ? 21  ASP D OD2  1 
ATOM   5710  N  N    . THR D 2 22  ? 59.492  -6.450  5.304   1.00 71.49  ? 22  THR D N    1 
ATOM   5711  C  CA   . THR D 2 22  ? 60.616  -6.288  6.219   1.00 69.41  ? 22  THR D CA   1 
ATOM   5712  C  C    . THR D 2 22  ? 60.386  -7.129  7.477   1.00 67.22  ? 22  THR D C    1 
ATOM   5713  O  O    . THR D 2 22  ? 59.270  -7.597  7.756   1.00 68.06  ? 22  THR D O    1 
ATOM   5714  C  CB   . THR D 2 22  ? 60.820  -4.814  6.618   1.00 64.57  ? 22  THR D CB   1 
ATOM   5715  O  OG1  . THR D 2 22  ? 59.754  -4.380  7.480   1.00 64.00  ? 22  THR D OG1  1 
ATOM   5716  C  CG2  . THR D 2 22  ? 60.930  -3.906  5.395   1.00 61.46  ? 22  THR D CG2  1 
ATOM   5717  N  N    . ILE D 2 23  ? 61.452  -7.287  8.266   1.00 64.42  ? 23  ILE D N    1 
ATOM   5718  C  CA   . ILE D 2 23  ? 61.305  -7.939  9.569   1.00 64.99  ? 23  ILE D CA   1 
ATOM   5719  C  C    . ILE D 2 23  ? 60.353  -7.144  10.466  1.00 63.47  ? 23  ILE D C    1 
ATOM   5720  O  O    . ILE D 2 23  ? 59.528  -7.730  11.186  1.00 65.52  ? 23  ILE D O    1 
ATOM   5721  C  CB   . ILE D 2 23  ? 62.687  -8.156  10.222  1.00 61.92  ? 23  ILE D CB   1 
ATOM   5722  C  CG1  . ILE D 2 23  ? 63.624  -8.885  9.251   1.00 54.94  ? 23  ILE D CG1  1 
ATOM   5723  C  CG2  . ILE D 2 23  ? 62.555  -8.947  11.503  1.00 55.87  ? 23  ILE D CG2  1 
ATOM   5724  C  CD1  . ILE D 2 23  ? 62.963  -10.071 8.532   1.00 60.78  ? 23  ILE D CD1  1 
ATOM   5725  N  N    . GLU D 2 24  ? 60.441  -5.816  10.406  1.00 61.20  ? 24  GLU D N    1 
ATOM   5726  C  CA   . GLU D 2 24  ? 59.557  -4.951  11.223  1.00 62.43  ? 24  GLU D CA   1 
ATOM   5727  C  C    . GLU D 2 24  ? 58.090  -5.256  10.915  1.00 64.42  ? 24  GLU D C    1 
ATOM   5728  O  O    . GLU D 2 24  ? 57.306  -5.348  11.868  1.00 63.14  ? 24  GLU D O    1 
ATOM   5729  C  CB   . GLU D 2 24  ? 59.847  -3.482  10.942  1.00 65.62  ? 24  GLU D CB   1 
ATOM   5730  C  CG   . GLU D 2 24  ? 61.214  -3.027  11.383  1.00 61.88  ? 24  GLU D CG   1 
ATOM   5731  C  CD   . GLU D 2 24  ? 62.087  -2.569  10.233  1.00 73.33  ? 24  GLU D CD   1 
ATOM   5732  O  OE1  . GLU D 2 24  ? 62.054  -3.223  9.184   1.00 75.18  ? 24  GLU D OE1  1 
ATOM   5733  O  OE2  . GLU D 2 24  ? 62.803  -1.567  10.395  1.00 78.33  ? 24  GLU D OE2  1 
ATOM   5734  N  N    . ASN D 2 25  ? 57.742  -5.410  9.635   1.00 65.06  ? 25  ASN D N    1 
ATOM   5735  C  CA   . ASN D 2 25  ? 56.343  -5.749  9.254   1.00 65.30  ? 25  ASN D CA   1 
ATOM   5736  C  C    . ASN D 2 25  ? 55.989  -7.126  9.813   1.00 61.49  ? 25  ASN D C    1 
ATOM   5737  O  O    . ASN D 2 25  ? 54.857  -7.296  10.266  1.00 59.89  ? 25  ASN D O    1 
ATOM   5738  C  CB   . ASN D 2 25  ? 56.080  -5.708  7.745   1.00 64.95  ? 25  ASN D CB   1 
ATOM   5739  C  CG   . ASN D 2 25  ? 56.589  -4.466  7.049   1.00 75.23  ? 25  ASN D CG   1 
ATOM   5740  O  OD1  . ASN D 2 25  ? 57.114  -4.550  5.942   1.00 74.03  ? 25  ASN D OD1  1 
ATOM   5741  N  ND2  . ASN D 2 25  ? 56.428  -3.313  7.676   1.00 78.97  ? 25  ASN D ND2  1 
ATOM   5742  N  N    . VAL D 2 26  ? 56.932  -8.062  9.772   1.00 58.66  ? 26  VAL D N    1 
ATOM   5743  C  CA   . VAL D 2 26  ? 56.646  -9.442  10.250  1.00 62.95  ? 26  VAL D CA   1 
ATOM   5744  C  C    . VAL D 2 26  ? 56.410  -9.390  11.761  1.00 59.65  ? 26  VAL D C    1 
ATOM   5745  O  O    . VAL D 2 26  ? 55.435  -9.984  12.208  1.00 58.14  ? 26  VAL D O    1 
ATOM   5746  C  CB   . VAL D 2 26  ? 57.756  -10.430 9.845   1.00 60.87  ? 26  VAL D CB   1 
ATOM   5747  C  CG1  . VAL D 2 26  ? 57.591  -11.790 10.502  1.00 52.91  ? 26  VAL D CG1  1 
ATOM   5748  C  CG2  . VAL D 2 26  ? 57.825  -10.582 8.338   1.00 49.48  ? 26  VAL D CG2  1 
ATOM   5749  N  N    . LYS D 2 27  ? 57.234  -8.645  12.492  1.00 59.12  ? 27  LYS D N    1 
ATOM   5750  C  CA   . LYS D 2 27  ? 57.073  -8.537  13.961  1.00 57.13  ? 27  LYS D CA   1 
ATOM   5751  C  C    . LYS D 2 27  ? 55.708  -7.927  14.280  1.00 60.99  ? 27  LYS D C    1 
ATOM   5752  O  O    . LYS D 2 27  ? 55.080  -8.367  15.241  1.00 59.93  ? 27  LYS D O    1 
ATOM   5753  C  CB   . LYS D 2 27  ? 58.204  -7.704  14.558  1.00 61.92  ? 27  LYS D CB   1 
ATOM   5754  C  CG   . LYS D 2 27  ? 59.556  -8.386  14.657  1.00 58.89  ? 27  LYS D CG   1 
ATOM   5755  C  CD   . LYS D 2 27  ? 60.671  -7.408  14.928  1.00 59.24  ? 27  LYS D CD   1 
ATOM   5756  C  CE   . LYS D 2 27  ? 61.961  -8.087  15.328  1.00 57.25  ? 27  LYS D CE   1 
ATOM   5757  N  NZ   . LYS D 2 27  ? 63.040  -7.106  15.581  1.00 53.77  ? 27  LYS D NZ   1 
ATOM   5758  N  N    . ALA D 2 28  ? 55.268  -6.963  13.481  1.00 62.30  ? 28  ALA D N    1 
ATOM   5759  C  CA   . ALA D 2 28  ? 53.948  -6.332  13.692  1.00 59.18  ? 28  ALA D CA   1 
ATOM   5760  C  C    . ALA D 2 28  ? 52.834  -7.349  13.469  1.00 57.11  ? 28  ALA D C    1 
ATOM   5761  O  O    . ALA D 2 28  ? 51.850  -7.291  14.194  1.00 61.08  ? 28  ALA D O    1 
ATOM   5762  C  CB   . ALA D 2 28  ? 53.790  -5.161  12.768  1.00 54.09  ? 28  ALA D CB   1 
ATOM   5763  N  N    . LYS D 2 29  ? 52.978  -8.211  12.471  1.00 53.78  ? 29  LYS D N    1 
ATOM   5764  C  CA   . LYS D 2 29  ? 51.963  -9.260  12.212  1.00 57.26  ? 29  LYS D CA   1 
ATOM   5765  C  C    . LYS D 2 29  ? 51.977  -10.264 13.363  1.00 58.69  ? 29  LYS D C    1 
ATOM   5766  O  O    . LYS D 2 29  ? 50.925  -10.825 13.658  1.00 55.73  ? 29  LYS D O    1 
ATOM   5767  C  CB   . LYS D 2 29  ? 52.232  -9.932  10.867  1.00 60.23  ? 29  LYS D CB   1 
ATOM   5768  C  CG   . LYS D 2 29  ? 52.047  -9.053  9.641   1.00 59.70  ? 29  LYS D CG   1 
ATOM   5769  C  CD   . LYS D 2 29  ? 52.839  -9.536  8.450   1.00 66.33  ? 29  LYS D CD   1 
ATOM   5770  C  CE   . LYS D 2 29  ? 53.090  -8.451  7.427   1.00 62.70  ? 29  LYS D CE   1 
ATOM   5771  N  NZ   . LYS D 2 29  ? 52.352  -8.703  6.169   1.00 66.06  ? 29  LYS D NZ   1 
ATOM   5772  N  N    . ILE D 2 30  ? 53.135  -10.491 13.972  1.00 59.71  ? 30  ILE D N    1 
ATOM   5773  C  CA   . ILE D 2 30  ? 53.155  -11.368 15.173  1.00 61.19  ? 30  ILE D CA   1 
ATOM   5774  C  C    . ILE D 2 30  ? 52.454  -10.603 16.292  1.00 56.91  ? 30  ILE D C    1 
ATOM   5775  O  O    . ILE D 2 30  ? 51.622  -11.195 16.926  1.00 65.29  ? 30  ILE D O    1 
ATOM   5776  C  CB   . ILE D 2 30  ? 54.578  -11.846 15.518  1.00 60.04  ? 30  ILE D CB   1 
ATOM   5777  C  CG1  . ILE D 2 30  ? 55.131  -12.732 14.403  1.00 59.79  ? 30  ILE D CG1  1 
ATOM   5778  C  CG2  . ILE D 2 30  ? 54.615  -12.562 16.857  1.00 55.57  ? 30  ILE D CG2  1 
ATOM   5779  C  CD1  . ILE D 2 30  ? 56.618  -12.659 14.244  1.00 53.48  ? 30  ILE D CD1  1 
ATOM   5780  N  N    . GLN D 2 31  ? 52.732  -9.315  16.478  1.00 57.94  ? 31  GLN D N    1 
ATOM   5781  C  CA   . GLN D 2 31  ? 51.950  -8.575  17.484  1.00 63.34  ? 31  GLN D CA   1 
ATOM   5782  C  C    . GLN D 2 31  ? 50.452  -8.643  17.198  1.00 60.18  ? 31  GLN D C    1 
ATOM   5783  O  O    . GLN D 2 31  ? 49.653  -8.924  18.097  1.00 57.30  ? 31  GLN D O    1 
ATOM   5784  C  CB   . GLN D 2 31  ? 52.394  -7.107  17.560  1.00 59.57  ? 31  GLN D CB   1 
ATOM   5785  C  CG   . GLN D 2 31  ? 51.577  -6.295  18.573  1.00 60.91  ? 31  GLN D CG   1 
ATOM   5786  C  CD   . GLN D 2 31  ? 51.992  -4.826  18.674  1.00 60.55  ? 31  GLN D CD   1 
ATOM   5787  O  OE1  . GLN D 2 31  ? 52.334  -4.182  17.687  1.00 65.25  ? 31  GLN D OE1  1 
ATOM   5788  N  NE2  . GLN D 2 31  ? 51.964  -4.303  19.877  1.00 62.97  ? 31  GLN D NE2  1 
ATOM   5789  N  N    . ASP D 2 32  ? 50.058  -8.330  15.958  1.00 58.92  ? 32  ASP D N    1 
ATOM   5790  C  CA   . ASP D 2 32  ? 48.700  -8.551  15.460  1.00 59.03  ? 32  ASP D CA   1 
ATOM   5791  C  C    . ASP D 2 32  ? 48.089  -9.859  15.949  1.00 65.16  ? 32  ASP D C    1 
ATOM   5792  O  O    . ASP D 2 32  ? 46.953  -9.883  16.447  1.00 62.44  ? 32  ASP D O    1 
ATOM   5793  C  CB   . ASP D 2 32  ? 48.747  -8.549  13.924  1.00 61.33  ? 32  ASP D CB   1 
ATOM   5794  C  CG   . ASP D 2 32  ? 47.557  -7.878  13.293  1.00 61.54  ? 32  ASP D CG   1 
ATOM   5795  O  OD1  . ASP D 2 32  ? 47.334  -6.687  13.649  1.00 60.30  ? 32  ASP D OD1  1 
ATOM   5796  O  OD2  . ASP D 2 32  ? 46.886  -8.519  12.426  1.00 57.40  ? 32  ASP D OD2  1 
ATOM   5797  N  N    . LYS D 2 33  ? 48.831  -10.969 15.802  1.00 62.75  ? 33  LYS D N    1 
ATOM   5798  C  CA   . LYS D 2 33  ? 48.261  -12.297 16.000  1.00 59.29  ? 33  LYS D CA   1 
ATOM   5799  C  C    . LYS D 2 33  ? 48.604  -12.910 17.337  1.00 60.04  ? 33  LYS D C    1 
ATOM   5800  O  O    . LYS D 2 33  ? 47.854  -13.765 17.816  1.00 62.65  ? 33  LYS D O    1 
ATOM   5801  C  CB   . LYS D 2 33  ? 48.720  -13.256 14.894  1.00 55.09  ? 33  LYS D CB   1 
ATOM   5802  C  CG   . LYS D 2 33  ? 47.955  -14.574 14.847  1.00 50.87  ? 33  LYS D CG   1 
ATOM   5803  C  CD   . LYS D 2 33  ? 48.062  -15.190 13.448  1.00 57.72  ? 33  LYS D CD   1 
ATOM   5804  C  CE   . LYS D 2 33  ? 47.317  -16.516 13.337  1.00 52.18  ? 33  LYS D CE   1 
ATOM   5805  N  NZ   . LYS D 2 33  ? 47.477  -17.118 11.979  1.00 53.71  ? 33  LYS D NZ   1 
ATOM   5806  N  N    . GLU D 2 34  ? 49.715  -12.507 17.946  1.00 59.75  ? 34  GLU D N    1 
ATOM   5807  C  CA   . GLU D 2 34  ? 50.148  -13.097 19.200  1.00 64.46  ? 34  GLU D CA   1 
ATOM   5808  C  C    . GLU D 2 34  ? 50.195  -12.131 20.374  1.00 67.13  ? 34  GLU D C    1 
ATOM   5809  O  O    . GLU D 2 34  ? 50.213  -12.597 21.516  1.00 72.30  ? 34  GLU D O    1 
ATOM   5810  C  CB   . GLU D 2 34  ? 51.527  -13.747 19.038  1.00 66.35  ? 34  GLU D CB   1 
ATOM   5811  C  CG   . GLU D 2 34  ? 51.420  -15.200 18.705  1.00 60.48  ? 34  GLU D CG   1 
ATOM   5812  C  CD   . GLU D 2 34  ? 51.107  -16.022 19.909  1.00 61.85  ? 34  GLU D CD   1 
ATOM   5813  O  OE1  . GLU D 2 34  ? 51.985  -16.108 20.795  1.00 64.83  ? 34  GLU D OE1  1 
ATOM   5814  O  OE2  . GLU D 2 34  ? 49.990  -16.585 19.965  1.00 66.75  ? 34  GLU D OE2  1 
ATOM   5815  N  N    . GLY D 2 35  ? 50.190  -10.822 20.142  1.00 62.29  ? 35  GLY D N    1 
ATOM   5816  C  CA   . GLY D 2 35  ? 50.142  -9.870  21.229  1.00 59.01  ? 35  GLY D CA   1 
ATOM   5817  C  C    . GLY D 2 35  ? 51.486  -9.451  21.775  1.00 69.24  ? 35  GLY D C    1 
ATOM   5818  O  O    . GLY D 2 35  ? 51.529  -8.779  22.816  1.00 72.53  ? 35  GLY D O    1 
ATOM   5819  N  N    . ILE D 2 36  ? 52.577  -9.819  21.109  1.00 66.39  ? 36  ILE D N    1 
ATOM   5820  C  CA   . ILE D 2 36  ? 53.927  -9.513  21.573  1.00 64.65  ? 36  ILE D CA   1 
ATOM   5821  C  C    . ILE D 2 36  ? 54.353  -8.194  20.939  1.00 66.92  ? 36  ILE D C    1 
ATOM   5822  O  O    . ILE D 2 36  ? 54.411  -8.111  19.704  1.00 68.12  ? 36  ILE D O    1 
ATOM   5823  C  CB   . ILE D 2 36  ? 54.915  -10.621 21.199  1.00 59.59  ? 36  ILE D CB   1 
ATOM   5824  C  CG1  . ILE D 2 36  ? 54.324  -12.009 21.493  1.00 67.14  ? 36  ILE D CG1  1 
ATOM   5825  C  CG2  . ILE D 2 36  ? 56.256  -10.375 21.864  1.00 61.66  ? 36  ILE D CG2  1 
ATOM   5826  C  CD1  . ILE D 2 36  ? 54.098  -12.289 22.947  1.00 70.18  ? 36  ILE D CD1  1 
ATOM   5827  N  N    . PRO D 2 37  ? 54.683  -7.172  21.721  1.00 63.24  ? 37  PRO D N    1 
ATOM   5828  C  CA   . PRO D 2 37  ? 55.176  -5.918  21.135  1.00 67.35  ? 37  PRO D CA   1 
ATOM   5829  C  C    . PRO D 2 37  ? 56.433  -6.161  20.322  1.00 64.29  ? 37  PRO D C    1 
ATOM   5830  O  O    . PRO D 2 37  ? 57.354  -6.837  20.798  1.00 63.82  ? 37  PRO D O    1 
ATOM   5831  C  CB   . PRO D 2 37  ? 55.466  -5.046  22.362  1.00 60.32  ? 37  PRO D CB   1 
ATOM   5832  C  CG   . PRO D 2 37  ? 54.587  -5.607  23.415  1.00 62.62  ? 37  PRO D CG   1 
ATOM   5833  C  CD   . PRO D 2 37  ? 54.563  -7.084  23.180  1.00 63.93  ? 37  PRO D CD   1 
ATOM   5834  N  N    . PRO D 2 38  ? 56.503  -5.633  19.097  1.00 60.40  ? 38  PRO D N    1 
ATOM   5835  C  CA   . PRO D 2 38  ? 57.680  -5.883  18.249  1.00 59.65  ? 38  PRO D CA   1 
ATOM   5836  C  C    . PRO D 2 38  ? 59.001  -5.612  18.929  1.00 60.14  ? 38  PRO D C    1 
ATOM   5837  O  O    . PRO D 2 38  ? 60.001  -6.241  18.576  1.00 65.17  ? 38  PRO D O    1 
ATOM   5838  C  CB   . PRO D 2 38  ? 57.460  -4.931  17.067  1.00 56.77  ? 38  PRO D CB   1 
ATOM   5839  C  CG   . PRO D 2 38  ? 55.970  -4.765  17.003  1.00 57.82  ? 38  PRO D CG   1 
ATOM   5840  C  CD   . PRO D 2 38  ? 55.479  -4.826  18.411  1.00 57.71  ? 38  PRO D CD   1 
ATOM   5841  N  N    . ASP D 2 39  ? 59.039  -4.693  19.898  1.00 66.44  ? 39  ASP D N    1 
ATOM   5842  C  CA   . ASP D 2 39  ? 60.299  -4.337  20.545  1.00 62.38  ? 39  ASP D CA   1 
ATOM   5843  C  C    . ASP D 2 39  ? 60.883  -5.505  21.313  1.00 58.99  ? 39  ASP D C    1 
ATOM   5844  O  O    . ASP D 2 39  ? 62.101  -5.614  21.447  1.00 60.35  ? 39  ASP D O    1 
ATOM   5845  C  CB   . ASP D 2 39  ? 60.082  -3.163  21.490  1.00 67.14  ? 39  ASP D CB   1 
ATOM   5846  C  CG   . ASP D 2 39  ? 59.869  -1.876  20.752  1.00 76.05  ? 39  ASP D CG   1 
ATOM   5847  O  OD1  . ASP D 2 39  ? 60.559  -1.674  19.721  1.00 74.54  ? 39  ASP D OD1  1 
ATOM   5848  O  OD2  . ASP D 2 39  ? 59.009  -1.082  21.195  1.00 77.70  ? 39  ASP D OD2  1 
ATOM   5849  N  N    . GLN D 2 40  ? 60.032  -6.373  21.839  1.00 61.99  ? 40  GLN D N    1 
ATOM   5850  C  CA   . GLN D 2 40  ? 60.471  -7.536  22.590  1.00 66.96  ? 40  GLN D CA   1 
ATOM   5851  C  C    . GLN D 2 40  ? 60.762  -8.761  21.723  1.00 59.39  ? 40  GLN D C    1 
ATOM   5852  O  O    . GLN D 2 40  ? 61.269  -9.756  22.249  1.00 58.82  ? 40  GLN D O    1 
ATOM   5853  C  CB   . GLN D 2 40  ? 59.411  -7.896  23.648  1.00 62.66  ? 40  GLN D CB   1 
ATOM   5854  C  CG   . GLN D 2 40  ? 59.378  -6.951  24.838  1.00 61.72  ? 40  GLN D CG   1 
ATOM   5855  C  CD   . GLN D 2 40  ? 57.988  -6.422  25.089  1.00 74.71  ? 40  GLN D CD   1 
ATOM   5856  O  OE1  . GLN D 2 40  ? 57.054  -7.196  25.341  1.00 75.71  ? 40  GLN D OE1  1 
ATOM   5857  N  NE2  . GLN D 2 40  ? 57.824  -5.096  24.974  1.00 68.88  ? 40  GLN D NE2  1 
ATOM   5858  N  N    . GLN D 2 41  ? 60.413  -8.706  20.447  1.00 60.86  ? 41  GLN D N    1 
ATOM   5859  C  CA   . GLN D 2 41  ? 60.492  -9.932  19.620  1.00 59.68  ? 41  GLN D CA   1 
ATOM   5860  C  C    . GLN D 2 41  ? 61.863  -10.211 19.027  1.00 58.66  ? 41  GLN D C    1 
ATOM   5861  O  O    . GLN D 2 41  ? 62.520  -9.269  18.582  1.00 51.28  ? 41  GLN D O    1 
ATOM   5862  C  CB   . GLN D 2 41  ? 59.514  -9.833  18.457  1.00 56.24  ? 41  GLN D CB   1 
ATOM   5863  C  CG   . GLN D 2 41  ? 58.064  -9.715  18.871  1.00 54.81  ? 41  GLN D CG   1 
ATOM   5864  C  CD   . GLN D 2 41  ? 57.173  -9.837  17.664  1.00 60.80  ? 41  GLN D CD   1 
ATOM   5865  O  OE1  . GLN D 2 41  ? 57.527  -10.475 16.680  1.00 51.50  ? 41  GLN D OE1  1 
ATOM   5866  N  NE2  . GLN D 2 41  ? 56.012  -9.214  17.729  1.00 61.79  ? 41  GLN D NE2  1 
ATOM   5867  N  N    . ARG D 2 42  ? 62.256  -11.478 19.070  1.00 57.02  ? 42  ARG D N    1 
ATOM   5868  C  CA   . ARG D 2 42  ? 63.505  -11.921 18.414  1.00 53.47  ? 42  ARG D CA   1 
ATOM   5869  C  C    . ARG D 2 42  ? 63.105  -13.106 17.537  1.00 54.79  ? 42  ARG D C    1 
ATOM   5870  O  O    . ARG D 2 42  ? 62.500  -14.040 18.054  1.00 53.37  ? 42  ARG D O    1 
ATOM   5871  C  CB   . ARG D 2 42  ? 64.590  -12.223 19.442  1.00 53.52  ? 42  ARG D CB   1 
ATOM   5872  C  CG   . ARG D 2 42  ? 64.970  -11.054 20.337  1.00 56.74  ? 42  ARG D CG   1 
ATOM   5873  C  CD   . ARG D 2 42  ? 66.102  -11.439 21.261  1.00 52.44  ? 42  ARG D CD   1 
ATOM   5874  N  NE   . ARG D 2 42  ? 66.941  -12.423 20.608  1.00 64.59  ? 42  ARG D NE   1 
ATOM   5875  C  CZ   . ARG D 2 42  ? 67.397  -13.532 21.161  1.00 57.12  ? 42  ARG D CZ   1 
ATOM   5876  N  NH1  . ARG D 2 42  ? 67.129  -13.815 22.423  1.00 48.85  ? 42  ARG D NH1  1 
ATOM   5877  N  NH2  . ARG D 2 42  ? 68.131  -14.350 20.434  1.00 53.84  ? 42  ARG D NH2  1 
ATOM   5878  N  N    . LEU D 2 43  ? 63.436  -13.058 16.258  1.00 58.46  ? 43  LEU D N    1 
ATOM   5879  C  CA   . LEU D 2 43  ? 63.022  -14.030 15.260  1.00 50.05  ? 43  LEU D CA   1 
ATOM   5880  C  C    . LEU D 2 43  ? 64.260  -14.783 14.791  1.00 52.91  ? 43  LEU D C    1 
ATOM   5881  O  O    . LEU D 2 43  ? 65.174  -14.193 14.190  1.00 52.96  ? 43  LEU D O    1 
ATOM   5882  C  CB   . LEU D 2 43  ? 62.325  -13.322 14.103  1.00 46.72  ? 43  LEU D CB   1 
ATOM   5883  C  CG   . LEU D 2 43  ? 60.985  -12.710 14.510  1.00 50.81  ? 43  LEU D CG   1 
ATOM   5884  C  CD1  . LEU D 2 43  ? 60.436  -11.858 13.403  1.00 51.45  ? 43  LEU D CD1  1 
ATOM   5885  C  CD2  . LEU D 2 43  ? 60.029  -13.829 14.842  1.00 48.37  ? 43  LEU D CD2  1 
ATOM   5886  N  N    . ILE D 2 44  ? 64.296  -16.084 15.063  1.00 52.89  ? 44  ILE D N    1 
ATOM   5887  C  CA   . ILE D 2 44  ? 65.437  -16.918 14.705  1.00 50.82  ? 44  ILE D CA   1 
ATOM   5888  C  C    . ILE D 2 44  ? 65.038  -17.836 13.561  1.00 51.74  ? 44  ILE D C    1 
ATOM   5889  O  O    . ILE D 2 44  ? 63.957  -18.441 13.575  1.00 48.72  ? 44  ILE D O    1 
ATOM   5890  C  CB   . ILE D 2 44  ? 65.960  -17.699 15.916  1.00 50.22  ? 44  ILE D CB   1 
ATOM   5891  C  CG1  . ILE D 2 44  ? 66.438  -16.695 16.972  1.00 52.08  ? 44  ILE D CG1  1 
ATOM   5892  C  CG2  . ILE D 2 44  ? 67.115  -18.616 15.511  1.00 48.42  ? 44  ILE D CG2  1 
ATOM   5893  C  CD1  . ILE D 2 44  ? 66.769  -17.349 18.275  1.00 57.80  ? 44  ILE D CD1  1 
ATOM   5894  N  N    . PHE D 2 45  ? 65.892  -17.894 12.552  1.00 49.06  ? 45  PHE D N    1 
ATOM   5895  C  CA   . PHE D 2 45  ? 65.685  -18.758 11.406  1.00 53.67  ? 45  PHE D CA   1 
ATOM   5896  C  C    . PHE D 2 45  ? 67.040  -19.257 10.924  1.00 52.43  ? 45  PHE D C    1 
ATOM   5897  O  O    . PHE D 2 45  ? 67.925  -18.446 10.629  1.00 47.00  ? 45  PHE D O    1 
ATOM   5898  C  CB   . PHE D 2 45  ? 64.967  -18.015 10.281  1.00 52.25  ? 45  PHE D CB   1 
ATOM   5899  C  CG   . PHE D 2 45  ? 64.859  -18.809 9.043   1.00 47.77  ? 45  PHE D CG   1 
ATOM   5900  C  CD1  . PHE D 2 45  ? 63.915  -19.813 8.943   1.00 49.90  ? 45  PHE D CD1  1 
ATOM   5901  C  CD2  . PHE D 2 45  ? 65.720  -18.580 7.989   1.00 46.63  ? 45  PHE D CD2  1 
ATOM   5902  C  CE1  . PHE D 2 45  ? 63.817  -20.573 7.788   1.00 51.67  ? 45  PHE D CE1  1 
ATOM   5903  C  CE2  . PHE D 2 45  ? 65.640  -19.322 6.856   1.00 46.76  ? 45  PHE D CE2  1 
ATOM   5904  C  CZ   . PHE D 2 45  ? 64.677  -20.327 6.744   1.00 48.29  ? 45  PHE D CZ   1 
ATOM   5905  N  N    . ALA D 2 46  ? 67.195  -20.579 10.830  1.00 53.04  ? 46  ALA D N    1 
ATOM   5906  C  CA   . ALA D 2 46  ? 68.466  -21.204 10.388  1.00 47.54  ? 46  ALA D CA   1 
ATOM   5907  C  C    . ALA D 2 46  ? 69.646  -20.668 11.194  1.00 47.18  ? 46  ALA D C    1 
ATOM   5908  O  O    . ALA D 2 46  ? 70.738  -20.546 10.636  1.00 47.54  ? 46  ALA D O    1 
ATOM   5909  C  CB   . ALA D 2 46  ? 68.658  -21.025 8.909   1.00 49.23  ? 46  ALA D CB   1 
ATOM   5910  N  N    . GLY D 2 47  ? 69.414  -20.352 12.458  1.00 48.29  ? 47  GLY D N    1 
ATOM   5911  C  CA   . GLY D 2 47  ? 70.499  -19.926 13.302  1.00 49.18  ? 47  GLY D CA   1 
ATOM   5912  C  C    . GLY D 2 47  ? 70.843  -18.460 13.215  1.00 52.55  ? 47  GLY D C    1 
ATOM   5913  O  O    . GLY D 2 47  ? 71.696  -17.998 13.992  1.00 50.64  ? 47  GLY D O    1 
ATOM   5914  N  N    . LYS D 2 48  ? 70.211  -17.719 12.305  1.00 48.70  ? 48  LYS D N    1 
ATOM   5915  C  CA   . LYS D 2 48  ? 70.416  -16.287 12.161  1.00 50.76  ? 48  LYS D CA   1 
ATOM   5916  C  C    . LYS D 2 48  ? 69.259  -15.563 12.842  1.00 53.99  ? 48  LYS D C    1 
ATOM   5917  O  O    . LYS D 2 48  ? 68.107  -16.003 12.757  1.00 53.31  ? 48  LYS D O    1 
ATOM   5918  C  CB   . LYS D 2 48  ? 70.521  -15.892 10.674  1.00 45.72  ? 48  LYS D CB   1 
ATOM   5919  N  N    . GLN D 2 49  ? 69.562  -14.473 13.545  1.00 47.76  ? 49  GLN D N    1 
ATOM   5920  C  CA   . GLN D 2 49  ? 68.510  -13.615 14.079  1.00 56.51  ? 49  GLN D CA   1 
ATOM   5921  C  C    . GLN D 2 49  ? 68.115  -12.589 13.017  1.00 55.00  ? 49  GLN D C    1 
ATOM   5922  O  O    . GLN D 2 49  ? 68.957  -11.809 12.561  1.00 55.62  ? 49  GLN D O    1 
ATOM   5923  C  CB   . GLN D 2 49  ? 68.940  -12.907 15.366  1.00 51.45  ? 49  GLN D CB   1 
ATOM   5924  C  CG   . GLN D 2 49  ? 67.755  -12.229 16.057  1.00 51.25  ? 49  GLN D CG   1 
ATOM   5925  C  CD   . GLN D 2 49  ? 68.127  -11.455 17.302  1.00 54.31  ? 49  GLN D CD   1 
ATOM   5926  O  OE1  . GLN D 2 49  ? 68.651  -12.015 18.257  1.00 56.32  ? 49  GLN D OE1  1 
ATOM   5927  N  NE2  . GLN D 2 49  ? 67.825  -10.153 17.305  1.00 54.06  ? 49  GLN D NE2  1 
ATOM   5928  N  N    . LEU D 2 50  ? 66.844  -12.596 12.621  1.00 51.76  ? 50  LEU D N    1 
ATOM   5929  C  CA   . LEU D 2 50  ? 66.378  -11.682 11.585  1.00 57.54  ? 50  LEU D CA   1 
ATOM   5930  C  C    . LEU D 2 50  ? 66.518  -10.233 12.056  1.00 59.81  ? 50  LEU D C    1 
ATOM   5931  O  O    . LEU D 2 50  ? 66.216  -9.908  13.207  1.00 58.03  ? 50  LEU D O    1 
ATOM   5932  C  CB   . LEU D 2 50  ? 64.924  -12.010 11.223  1.00 52.16  ? 50  LEU D CB   1 
ATOM   5933  C  CG   . LEU D 2 50  ? 64.722  -13.495 10.873  1.00 53.54  ? 50  LEU D CG   1 
ATOM   5934  C  CD1  . LEU D 2 50  ? 63.291  -13.810 10.492  1.00 54.18  ? 50  LEU D CD1  1 
ATOM   5935  C  CD2  . LEU D 2 50  ? 65.650  -13.902 9.756   1.00 51.75  ? 50  LEU D CD2  1 
ATOM   5936  N  N    . GLU D 2 51  ? 67.009  -9.367  11.166  1.00 59.46  ? 51  GLU D N    1 
ATOM   5937  C  CA   . GLU D 2 51  ? 67.338  -7.981  11.495  1.00 63.02  ? 51  GLU D CA   1 
ATOM   5938  C  C    . GLU D 2 51  ? 66.350  -7.004  10.869  1.00 65.89  ? 51  GLU D C    1 
ATOM   5939  O  O    . GLU D 2 51  ? 66.123  -7.039  9.653   1.00 64.83  ? 51  GLU D O    1 
ATOM   5940  C  CB   . GLU D 2 51  ? 68.734  -7.601  11.003  1.00 68.70  ? 51  GLU D CB   1 
ATOM   5941  C  CG   . GLU D 2 51  ? 69.834  -8.617  11.168  1.00 65.17  ? 51  GLU D CG   1 
ATOM   5942  C  CD   . GLU D 2 51  ? 71.136  -8.091  10.579  1.00 73.99  ? 51  GLU D CD   1 
ATOM   5943  O  OE1  . GLU D 2 51  ? 72.143  -8.005  11.317  1.00 81.29  ? 51  GLU D OE1  1 
ATOM   5944  O  OE2  . GLU D 2 51  ? 71.149  -7.742  9.373   1.00 80.66  ? 51  GLU D OE2  1 
ATOM   5945  N  N    . ASP D 2 52  ? 65.812  -6.099  11.693  1.00 67.83  ? 52  ASP D N    1 
ATOM   5946  C  CA   . ASP D 2 52  ? 64.990  -4.997  11.197  1.00 68.80  ? 52  ASP D CA   1 
ATOM   5947  C  C    . ASP D 2 52  ? 65.632  -4.335  9.985   1.00 66.23  ? 52  ASP D C    1 
ATOM   5948  O  O    . ASP D 2 52  ? 66.853  -4.157  9.922   1.00 57.14  ? 52  ASP D O    1 
ATOM   5949  C  CB   . ASP D 2 52  ? 64.784  -3.951  12.294  1.00 66.78  ? 52  ASP D CB   1 
ATOM   5950  C  CG   . ASP D 2 52  ? 63.823  -4.408  13.345  1.00 65.90  ? 52  ASP D CG   1 
ATOM   5951  O  OD1  . ASP D 2 52  ? 63.144  -5.421  13.105  1.00 70.20  ? 52  ASP D OD1  1 
ATOM   5952  O  OD2  . ASP D 2 52  ? 63.750  -3.772  14.416  1.00 75.34  ? 52  ASP D OD2  1 
ATOM   5953  N  N    . GLY D 2 53  ? 64.794  -3.975  9.018   1.00 65.86  ? 53  GLY D N    1 
ATOM   5954  C  CA   . GLY D 2 53  ? 65.278  -3.371  7.802   1.00 69.66  ? 53  GLY D CA   1 
ATOM   5955  C  C    . GLY D 2 53  ? 65.810  -4.346  6.781   1.00 73.42  ? 53  GLY D C    1 
ATOM   5956  O  O    . GLY D 2 53  ? 66.293  -3.913  5.724   1.00 78.94  ? 53  GLY D O    1 
ATOM   5957  N  N    . ARG D 2 54  ? 65.759  -5.642  7.058   1.00 66.10  ? 54  ARG D N    1 
ATOM   5958  C  CA   . ARG D 2 54  ? 65.998  -6.638  6.031   1.00 65.83  ? 54  ARG D CA   1 
ATOM   5959  C  C    . ARG D 2 54  ? 64.671  -7.281  5.647   1.00 65.40  ? 54  ARG D C    1 
ATOM   5960  O  O    . ARG D 2 54  ? 63.662  -7.145  6.347   1.00 68.51  ? 54  ARG D O    1 
ATOM   5961  C  CB   . ARG D 2 54  ? 67.012  -7.681  6.507   1.00 66.67  ? 54  ARG D CB   1 
ATOM   5962  C  CG   . ARG D 2 54  ? 68.397  -7.092  6.765   1.00 63.81  ? 54  ARG D CG   1 
ATOM   5963  C  CD   . ARG D 2 54  ? 69.348  -7.399  5.614   1.00 69.97  ? 54  ARG D CD   1 
ATOM   5964  N  NE   . ARG D 2 54  ? 70.725  -6.983  5.887   1.00 76.35  ? 54  ARG D NE   1 
ATOM   5965  N  N    . THR D 2 55  ? 64.688  -7.983  4.514   1.00 67.28  ? 55  THR D N    1 
ATOM   5966  C  CA   . THR D 2 55  ? 63.446  -8.623  4.013   1.00 67.13  ? 55  THR D CA   1 
ATOM   5967  C  C    . THR D 2 55  ? 63.540  -10.147 4.134   1.00 63.42  ? 55  THR D C    1 
ATOM   5968  O  O    . THR D 2 55  ? 64.648  -10.661 4.296   1.00 62.12  ? 55  THR D O    1 
ATOM   5969  C  CB   . THR D 2 55  ? 63.109  -8.142  2.595   1.00 59.42  ? 55  THR D CB   1 
ATOM   5970  O  OG1  . THR D 2 55  ? 61.867  -8.739  2.239   1.00 72.21  ? 55  THR D OG1  1 
ATOM   5971  C  CG2  . THR D 2 55  ? 64.129  -8.512  1.548   1.00 61.66  ? 55  THR D CG2  1 
ATOM   5972  N  N    . LEU D 2 56  ? 62.400  -10.827 4.074   1.00 58.27  ? 56  LEU D N    1 
ATOM   5973  C  CA   . LEU D 2 56  ? 62.374  -12.303 4.175   1.00 55.50  ? 56  LEU D CA   1 
ATOM   5974  C  C    . LEU D 2 56  ? 63.108  -12.904 2.980   1.00 60.59  ? 56  LEU D C    1 
ATOM   5975  O  O    . LEU D 2 56  ? 63.730  -13.957 3.155   1.00 63.65  ? 56  LEU D O    1 
ATOM   5976  C  CB   . LEU D 2 56  ? 60.915  -12.750 4.210   1.00 52.76  ? 56  LEU D CB   1 
ATOM   5977  C  CG   . LEU D 2 56  ? 60.085  -12.227 5.377   1.00 55.88  ? 56  LEU D CG   1 
ATOM   5978  C  CD1  . LEU D 2 56  ? 58.670  -12.757 5.286   1.00 51.84  ? 56  LEU D CD1  1 
ATOM   5979  C  CD2  . LEU D 2 56  ? 60.702  -12.622 6.705   1.00 59.10  ? 56  LEU D CD2  1 
ATOM   5980  N  N    . SER D 2 57  ? 63.056  -12.243 1.826   1.00 60.76  ? 57  SER D N    1 
ATOM   5981  C  CA   . SER D 2 57  ? 63.763  -12.719 0.611   1.00 64.08  ? 57  SER D CA   1 
ATOM   5982  C  C    . SER D 2 57  ? 65.265  -12.821 0.876   1.00 61.50  ? 57  SER D C    1 
ATOM   5983  O  O    . SER D 2 57  ? 65.899  -13.717 0.309   1.00 57.05  ? 57  SER D O    1 
ATOM   5984  C  CB   . SER D 2 57  ? 63.465  -11.817 -0.561  1.00 64.47  ? 57  SER D CB   1 
ATOM   5985  O  OG   . SER D 2 57  ? 64.545  -10.941 -0.849  1.00 66.61  ? 57  SER D OG   1 
ATOM   5986  N  N    . ASP D 2 58  ? 65.799  -11.926 1.698   1.00 57.79  ? 58  ASP D N    1 
ATOM   5987  C  CA   . ASP D 2 58  ? 67.260  -11.907 1.953   1.00 61.53  ? 58  ASP D CA   1 
ATOM   5988  C  C    . ASP D 2 58  ? 67.672  -13.144 2.754   1.00 59.82  ? 58  ASP D C    1 
ATOM   5989  O  O    . ASP D 2 58  ? 68.870  -13.442 2.764   1.00 65.14  ? 58  ASP D O    1 
ATOM   5990  C  CB   . ASP D 2 58  ? 67.679  -10.618 2.664   1.00 65.26  ? 58  ASP D CB   1 
ATOM   5991  C  CG   . ASP D 2 58  ? 67.432  -9.347  1.877   1.00 68.98  ? 58  ASP D CG   1 
ATOM   5992  O  OD1  . ASP D 2 58  ? 67.350  -9.426  0.638   1.00 71.37  ? 58  ASP D OD1  1 
ATOM   5993  O  OD2  . ASP D 2 58  ? 67.317  -8.288  2.516   1.00 65.94  ? 58  ASP D OD2  1 
ATOM   5994  N  N    . TYR D 2 59  ? 66.722  -13.822 3.396   1.00 55.39  ? 59  TYR D N    1 
ATOM   5995  C  CA   . TYR D 2 59  ? 67.047  -14.987 4.252   1.00 54.95  ? 59  TYR D CA   1 
ATOM   5996  C  C    . TYR D 2 59  ? 66.472  -16.266 3.647   1.00 58.92  ? 59  TYR D C    1 
ATOM   5997  O  O    . TYR D 2 59  ? 66.463  -17.281 4.345   1.00 63.63  ? 59  TYR D O    1 
ATOM   5998  C  CB   . TYR D 2 59  ? 66.484  -14.780 5.657   1.00 59.87  ? 59  TYR D CB   1 
ATOM   5999  C  CG   . TYR D 2 59  ? 67.024  -13.609 6.430   1.00 55.47  ? 59  TYR D CG   1 
ATOM   6000  C  CD1  . TYR D 2 59  ? 68.206  -13.710 7.141   1.00 51.73  ? 59  TYR D CD1  1 
ATOM   6001  C  CD2  . TYR D 2 59  ? 66.332  -12.412 6.487   1.00 59.14  ? 59  TYR D CD2  1 
ATOM   6002  C  CE1  . TYR D 2 59  ? 68.699  -12.644 7.872   1.00 56.19  ? 59  TYR D CE1  1 
ATOM   6003  C  CE2  . TYR D 2 59  ? 66.811  -11.336 7.211   1.00 56.03  ? 59  TYR D CE2  1 
ATOM   6004  C  CZ   . TYR D 2 59  ? 67.998  -11.454 7.906   1.00 55.05  ? 59  TYR D CZ   1 
ATOM   6005  O  OH   . TYR D 2 59  ? 68.481  -10.404 8.623   1.00 65.97  ? 59  TYR D OH   1 
ATOM   6006  N  N    . ASN D 2 60  ? 66.013  -16.213 2.402   1.00 56.80  ? 60  ASN D N    1 
ATOM   6007  C  CA   . ASN D 2 60  ? 65.428  -17.397 1.716   1.00 60.38  ? 60  ASN D CA   1 
ATOM   6008  C  C    . ASN D 2 60  ? 64.250  -17.951 2.525   1.00 53.09  ? 60  ASN D C    1 
ATOM   6009  O  O    . ASN D 2 60  ? 64.044  -19.168 2.495   1.00 58.53  ? 60  ASN D O    1 
ATOM   6010  C  CB   . ASN D 2 60  ? 66.494  -18.420 1.313   1.00 61.74  ? 60  ASN D CB   1 
ATOM   6011  C  CG   . ASN D 2 60  ? 67.227  -18.032 0.048   1.00 65.61  ? 60  ASN D CG   1 
ATOM   6012  O  OD1  . ASN D 2 60  ? 66.726  -17.245 -0.750  1.00 67.07  ? 60  ASN D OD1  1 
ATOM   6013  N  ND2  . ASN D 2 60  ? 68.415  -18.579 -0.142  1.00 71.18  ? 60  ASN D ND2  1 
ATOM   6014  N  N    . ILE D 2 61  ? 63.494  -17.080 3.189   1.00 58.24  ? 61  ILE D N    1 
ATOM   6015  C  CA   . ILE D 2 61  ? 62.251  -17.512 3.888   1.00 55.90  ? 61  ILE D CA   1 
ATOM   6016  C  C    . ILE D 2 61  ? 61.168  -17.630 2.818   1.00 54.38  ? 61  ILE D C    1 
ATOM   6017  O  O    . ILE D 2 61  ? 61.052  -16.720 1.987   1.00 48.68  ? 61  ILE D O    1 
ATOM   6018  C  CB   . ILE D 2 61  ? 61.890  -16.563 5.050   1.00 52.19  ? 61  ILE D CB   1 
ATOM   6019  C  CG1  . ILE D 2 61  ? 62.872  -16.731 6.209   1.00 55.18  ? 61  ILE D CG1  1 
ATOM   6020  C  CG2  . ILE D 2 61  ? 60.454  -16.745 5.513   1.00 45.98  ? 61  ILE D CG2  1 
ATOM   6021  C  CD1  . ILE D 2 61  ? 63.115  -15.475 6.994   1.00 56.25  ? 61  ILE D CD1  1 
ATOM   6022  N  N    . GLN D 2 62  ? 60.409  -18.715 2.856   1.00 51.24  ? 62  GLN D N    1 
ATOM   6023  C  CA   . GLN D 2 62  ? 59.440  -18.989 1.806   1.00 54.18  ? 62  GLN D CA   1 
ATOM   6024  C  C    . GLN D 2 62  ? 58.225  -19.640 2.445   1.00 50.72  ? 62  GLN D C    1 
ATOM   6025  O  O    . GLN D 2 62  ? 58.148  -19.801 3.668   1.00 53.49  ? 62  GLN D O    1 
ATOM   6026  C  CB   . GLN D 2 62  ? 60.036  -19.900 0.716   1.00 52.28  ? 62  GLN D CB   1 
ATOM   6027  C  CG   . GLN D 2 62  ? 60.491  -21.233 1.295   1.00 56.83  ? 62  GLN D CG   1 
ATOM   6028  C  CD   . GLN D 2 62  ? 61.006  -22.213 0.253   1.00 66.83  ? 62  GLN D CD   1 
ATOM   6029  O  OE1  . GLN D 2 62  ? 60.308  -22.530 -0.724  1.00 69.02  ? 62  GLN D OE1  1 
ATOM   6030  N  NE2  . GLN D 2 62  ? 62.232  -22.721 0.466   1.00 60.82  ? 62  GLN D NE2  1 
ATOM   6031  N  N    . LYS D 2 63  ? 57.293  -20.044 1.600   1.00 48.06  ? 63  LYS D N    1 
ATOM   6032  C  CA   . LYS D 2 63  ? 56.119  -20.763 2.119   1.00 55.18  ? 63  LYS D CA   1 
ATOM   6033  C  C    . LYS D 2 63  ? 56.582  -21.950 2.949   1.00 53.54  ? 63  LYS D C    1 
ATOM   6034  O  O    . LYS D 2 63  ? 57.484  -22.651 2.480   1.00 55.08  ? 63  LYS D O    1 
ATOM   6035  C  CB   . LYS D 2 63  ? 55.245  -21.265 0.973   1.00 49.22  ? 63  LYS D CB   1 
ATOM   6036  C  CG   . LYS D 2 63  ? 53.818  -21.620 1.356   1.00 52.21  ? 63  LYS D CG   1 
ATOM   6037  C  CD   . LYS D 2 63  ? 53.217  -22.676 0.467   1.00 50.52  ? 63  LYS D CD   1 
ATOM   6038  C  CE   . LYS D 2 63  ? 51.764  -22.945 0.785   1.00 59.28  ? 63  LYS D CE   1 
ATOM   6039  N  NZ   . LYS D 2 63  ? 51.593  -23.482 2.154   1.00 58.06  ? 63  LYS D NZ   1 
ATOM   6040  N  N    . GLU D 2 64  ? 56.026  -22.102 4.143   1.00 48.07  ? 64  GLU D N    1 
ATOM   6041  C  CA   . GLU D 2 64  ? 56.283  -23.266 5.029   1.00 49.09  ? 64  GLU D CA   1 
ATOM   6042  C  C    . GLU D 2 64  ? 57.570  -23.129 5.849   1.00 50.64  ? 64  GLU D C    1 
ATOM   6043  O  O    . GLU D 2 64  ? 57.808  -24.021 6.649   1.00 49.30  ? 64  GLU D O    1 
ATOM   6044  C  CB   . GLU D 2 64  ? 56.113  -24.587 4.279   1.00 44.33  ? 64  GLU D CB   1 
ATOM   6045  C  CG   . GLU D 2 64  ? 54.693  -24.837 3.823   1.00 50.65  ? 64  GLU D CG   1 
ATOM   6046  C  CD   . GLU D 2 64  ? 54.561  -26.082 2.971   1.00 54.32  ? 64  GLU D CD   1 
ATOM   6047  O  OE1  . GLU D 2 64  ? 55.244  -27.069 3.279   1.00 56.89  ? 64  GLU D OE1  1 
ATOM   6048  O  OE2  . GLU D 2 64  ? 53.785  -26.057 2.006   1.00 58.48  ? 64  GLU D OE2  1 
ATOM   6049  N  N    . SER D 2 65  ? 58.372  -22.079 5.668   1.00 42.53  ? 65  SER D N    1 
ATOM   6050  C  CA   . SER D 2 65  ? 59.476  -21.922 6.607   1.00 45.25  ? 65  SER D CA   1 
ATOM   6051  C  C    . SER D 2 65  ? 58.937  -21.632 8.001   1.00 42.96  ? 65  SER D C    1 
ATOM   6052  O  O    . SER D 2 65  ? 57.876  -21.035 8.166   1.00 42.43  ? 65  SER D O    1 
ATOM   6053  C  CB   . SER D 2 65  ? 60.420  -20.810 6.187   1.00 42.70  ? 65  SER D CB   1 
ATOM   6054  O  OG   . SER D 2 65  ? 60.543  -20.797 4.787   1.00 55.62  ? 65  SER D OG   1 
ATOM   6055  N  N    . THR D 2 66  ? 59.673  -22.088 9.007   1.00 45.11  ? 66  THR D N    1 
ATOM   6056  C  CA   . THR D 2 66  ? 59.344  -21.893 10.416  1.00 45.03  ? 66  THR D CA   1 
ATOM   6057  C  C    . THR D 2 66  ? 60.307  -20.877 11.019  1.00 47.44  ? 66  THR D C    1 
ATOM   6058  O  O    . THR D 2 66  ? 61.530  -21.043 10.949  1.00 46.51  ? 66  THR D O    1 
ATOM   6059  C  CB   . THR D 2 66  ? 59.436  -23.196 11.208  1.00 44.61  ? 66  THR D CB   1 
ATOM   6060  O  OG1  . THR D 2 66  ? 58.789  -24.262 10.497  1.00 50.43  ? 66  THR D OG1  1 
ATOM   6061  C  CG2  . THR D 2 66  ? 58.755  -23.027 12.549  1.00 45.03  ? 66  THR D CG2  1 
ATOM   6062  N  N    . LEU D 2 67  ? 59.724  -19.847 11.618  1.00 50.45  ? 67  LEU D N    1 
ATOM   6063  C  CA   . LEU D 2 67  ? 60.536  -18.860 12.349  1.00 45.15  ? 67  LEU D CA   1 
ATOM   6064  C  C    . LEU D 2 67  ? 60.401  -19.193 13.834  1.00 47.19  ? 67  LEU D C    1 
ATOM   6065  O  O    . LEU D 2 67  ? 59.337  -19.634 14.249  1.00 49.09  ? 67  LEU D O    1 
ATOM   6066  C  CB   . LEU D 2 67  ? 60.027  -17.451 12.043  1.00 42.87  ? 67  LEU D CB   1 
ATOM   6067  C  CG   . LEU D 2 67  ? 60.034  -17.005 10.585  1.00 50.29  ? 67  LEU D CG   1 
ATOM   6068  C  CD1  . LEU D 2 67  ? 59.781  -15.512 10.500  1.00 45.79  ? 67  LEU D CD1  1 
ATOM   6069  C  CD2  . LEU D 2 67  ? 61.347  -17.345 9.912   1.00 52.34  ? 67  LEU D CD2  1 
ATOM   6070  N  N    . HIS D 2 68  ? 61.467  -19.019 14.593  1.00 47.64  ? 68  HIS D N    1 
ATOM   6071  C  CA   . HIS D 2 68  ? 61.467  -19.283 16.022  1.00 51.41  ? 68  HIS D CA   1 
ATOM   6072  C  C    . HIS D 2 68  ? 61.463  -17.951 16.772  1.00 52.05  ? 68  HIS D C    1 
ATOM   6073  O  O    . HIS D 2 68  ? 62.404  -17.152 16.651  1.00 49.34  ? 68  HIS D O    1 
ATOM   6074  C  CB   . HIS D 2 68  ? 62.649  -20.187 16.377  1.00 44.59  ? 68  HIS D CB   1 
ATOM   6075  C  CG   . HIS D 2 68  ? 62.528  -21.543 15.752  1.00 53.68  ? 68  HIS D CG   1 
ATOM   6076  N  ND1  . HIS D 2 68  ? 63.161  -21.883 14.569  1.00 50.62  ? 68  HIS D ND1  1 
ATOM   6077  C  CD2  . HIS D 2 68  ? 61.774  -22.616 16.099  1.00 50.33  ? 68  HIS D CD2  1 
ATOM   6078  C  CE1  . HIS D 2 68  ? 62.831  -23.121 14.241  1.00 48.78  ? 68  HIS D CE1  1 
ATOM   6079  N  NE2  . HIS D 2 68  ? 61.979  -23.580 15.143  1.00 50.81  ? 68  HIS D NE2  1 
ATOM   6080  N  N    . LEU D 2 69  ? 60.366  -17.717 17.503  1.00 50.72  ? 69  LEU D N    1 
ATOM   6081  C  CA   . LEU D 2 69  ? 60.187  -16.448 18.251  1.00 53.44  ? 69  LEU D CA   1 
ATOM   6082  C  C    . LEU D 2 69  ? 60.652  -16.600 19.689  1.00 54.55  ? 69  LEU D C    1 
ATOM   6083  O  O    . LEU D 2 69  ? 60.175  -17.508 20.374  1.00 51.59  ? 69  LEU D O    1 
ATOM   6084  C  CB   . LEU D 2 69  ? 58.711  -16.050 18.227  1.00 52.54  ? 69  LEU D CB   1 
ATOM   6085  C  CG   . LEU D 2 69  ? 58.267  -15.026 19.268  1.00 52.62  ? 69  LEU D CG   1 
ATOM   6086  C  CD1  . LEU D 2 69  ? 58.752  -13.641 18.895  1.00 64.58  ? 69  LEU D CD1  1 
ATOM   6087  C  CD2  . LEU D 2 69  ? 56.758  -15.036 19.431  1.00 53.46  ? 69  LEU D CD2  1 
ATOM   6088  N  N    . VAL D 2 70  ? 61.610  -15.773 20.089  1.00 54.31  ? 70  VAL D N    1 
ATOM   6089  C  CA   . VAL D 2 70  ? 62.109  -15.791 21.489  1.00 54.87  ? 70  VAL D CA   1 
ATOM   6090  C  C    . VAL D 2 70  ? 62.065  -14.367 22.042  1.00 54.04  ? 70  VAL D C    1 
ATOM   6091  O  O    . VAL D 2 70  ? 61.938  -13.419 21.255  1.00 51.80  ? 70  VAL D O    1 
ATOM   6092  C  CB   . VAL D 2 70  ? 63.524  -16.385 21.581  1.00 48.63  ? 70  VAL D CB   1 
ATOM   6093  C  CG1  . VAL D 2 70  ? 63.566  -17.809 21.086  1.00 47.28  ? 70  VAL D CG1  1 
ATOM   6094  C  CG2  . VAL D 2 70  ? 64.539  -15.553 20.829  1.00 54.58  ? 70  VAL D CG2  1 
ATOM   6095  N  N    . LEU D 2 71  ? 62.126  -14.240 23.363  1.00 54.94  ? 71  LEU D N    1 
ATOM   6096  C  CA   . LEU D 2 71  ? 62.172  -12.903 23.997  1.00 58.10  ? 71  LEU D CA   1 
ATOM   6097  C  C    . LEU D 2 71  ? 63.598  -12.634 24.479  1.00 58.18  ? 71  LEU D C    1 
ATOM   6098  O  O    . LEU D 2 71  ? 64.545  -13.123 23.844  1.00 53.71  ? 71  LEU D O    1 
ATOM   6099  C  CB   . LEU D 2 71  ? 61.180  -12.842 25.162  1.00 58.69  ? 71  LEU D CB   1 
ATOM   6100  C  CG   . LEU D 2 71  ? 59.695  -12.859 24.813  1.00 59.33  ? 71  LEU D CG   1 
ATOM   6101  C  CD1  . LEU D 2 71  ? 58.870  -12.383 25.995  1.00 59.91  ? 71  LEU D CD1  1 
ATOM   6102  C  CD2  . LEU D 2 71  ? 59.400  -12.013 23.591  1.00 51.69  ? 71  LEU D CD2  1 
ATOM   6103  N  N    . ARG D 2 72  ? 63.738  -11.901 25.577  1.00 59.86  ? 72  ARG D N    1 
ATOM   6104  C  CA   . ARG D 2 72  ? 65.091  -11.504 26.022  1.00 58.64  ? 72  ARG D CA   1 
ATOM   6105  C  C    . ARG D 2 72  ? 65.234  -11.659 27.534  1.00 57.87  ? 72  ARG D C    1 
ATOM   6106  O  O    . ARG D 2 72  ? 64.280  -11.331 28.248  1.00 67.92  ? 72  ARG D O    1 
ATOM   6107  C  CB   . ARG D 2 72  ? 65.326  -10.051 25.617  1.00 53.42  ? 72  ARG D CB   1 
ATOM   6108  C  CG   . ARG D 2 72  ? 66.285  -9.843  24.459  1.00 47.45  ? 72  ARG D CG   1 
ATOM   6109  C  CD   . ARG D 2 72  ? 66.356  -8.358  24.184  1.00 54.28  ? 72  ARG D CD   1 
ATOM   6110  N  NE   . ARG D 2 72  ? 66.554  -8.035  22.783  1.00 51.30  ? 72  ARG D NE   1 
ATOM   6111  C  CZ   . ARG D 2 72  ? 65.614  -7.586  21.967  1.00 44.53  ? 72  ARG D CZ   1 
ATOM   6112  N  NH1  . ARG D 2 72  ? 64.382  -7.405  22.404  1.00 47.23  ? 72  ARG D NH1  1 
ATOM   6113  N  NH2  . ARG D 2 72  ? 65.911  -7.322  20.711  1.00 51.46  ? 72  ARG D NH2  1 
ATOM   6114  N  N    . LEU D 2 73  ? 66.367  -12.179 27.991  1.00 51.48  ? 73  LEU D N    1 
ATOM   6115  C  CA   . LEU D 2 73  ? 66.657  -12.247 29.442  1.00 58.01  ? 73  LEU D CA   1 
ATOM   6116  C  C    . LEU D 2 73  ? 67.930  -11.437 29.633  1.00 57.96  ? 73  LEU D C    1 
ATOM   6117  O  O    . LEU D 2 73  ? 69.006  -12.020 29.583  1.00 61.57  ? 73  LEU D O    1 
ATOM   6118  C  CB   . LEU D 2 73  ? 66.824  -13.700 29.881  1.00 57.75  ? 73  LEU D CB   1 
ATOM   6119  C  CG   . LEU D 2 73  ? 65.587  -14.354 30.489  1.00 55.69  ? 73  LEU D CG   1 
ATOM   6120  C  CD1  . LEU D 2 73  ? 65.957  -15.644 31.195  1.00 53.30  ? 73  LEU D CD1  1 
ATOM   6121  C  CD2  . LEU D 2 73  ? 64.897  -13.405 31.450  1.00 63.10  ? 73  LEU D CD2  1 
ATOM   6122  N  N    . ARG D 2 74  ? 67.767  -10.131 29.795  1.00 57.91  ? 74  ARG D N    1 
ATOM   6123  C  CA   . ARG D 2 74  ? 68.925  -9.216  29.901  1.00 64.34  ? 74  ARG D CA   1 
ATOM   6124  C  C    . ARG D 2 74  ? 69.623  -9.385  31.246  1.00 65.38  ? 74  ARG D C    1 
ATOM   6125  O  O    . ARG D 2 74  ? 68.940  -9.608  32.251  1.00 62.73  ? 74  ARG D O    1 
ATOM   6126  C  CB   . ARG D 2 74  ? 68.428  -7.791  29.662  1.00 63.83  ? 74  ARG D CB   1 
ATOM   6127  C  CG   . ARG D 2 74  ? 67.514  -7.658  28.453  1.00 57.99  ? 74  ARG D CG   1 
ATOM   6128  C  CD   . ARG D 2 74  ? 67.172  -6.223  28.116  1.00 58.95  ? 74  ARG D CD   1 
ATOM   6129  N  NE   . ARG D 2 74  ? 68.050  -5.698  27.083  1.00 63.11  ? 74  ARG D NE   1 
ATOM   6130  C  CZ   . ARG D 2 74  ? 67.642  -5.168  25.940  1.00 61.76  ? 74  ARG D CZ   1 
ATOM   6131  N  NH1  . ARG D 2 74  ? 66.353  -5.084  25.668  1.00 59.87  ? 74  ARG D NH1  1 
ATOM   6132  N  NH2  . ARG D 2 74  ? 68.521  -4.717  25.067  1.00 61.57  ? 74  ARG D NH2  1 
ATOM   6133  N  N    . GLY D 2 75  ? 70.944  -9.297  31.238  1.00 60.69  ? 75  GLY D N    1 
ATOM   6134  C  CA   . GLY D 2 75  ? 71.729  -9.449  32.439  1.00 58.73  ? 75  GLY D CA   1 
ATOM   6135  C  C    . GLY D 2 75  ? 72.967  -8.600  32.318  1.00 59.73  ? 75  GLY D C    1 
ATOM   6136  O  O    . GLY D 2 75  ? 73.533  -8.504  31.224  1.00 59.08  ? 75  GLY D O    1 
ATOM   6137  N  N    . THR E 1 4   ? 48.340  -65.476 26.761  1.00 81.23  ? 211 THR E N    1 
ATOM   6138  C  CA   . THR E 1 4   ? 49.340  -65.298 27.844  1.00 76.83  ? 211 THR E CA   1 
ATOM   6139  C  C    . THR E 1 4   ? 48.614  -65.282 29.183  1.00 79.34  ? 211 THR E C    1 
ATOM   6140  O  O    . THR E 1 4   ? 48.821  -66.227 29.960  1.00 83.99  ? 211 THR E O    1 
ATOM   6141  C  CB   . THR E 1 4   ? 50.170  -64.017 27.656  1.00 76.79  ? 211 THR E CB   1 
ATOM   6142  O  OG1  . THR E 1 4   ? 49.352  -62.851 27.758  1.00 76.78  ? 211 THR E OG1  1 
ATOM   6143  C  CG2  . THR E 1 4   ? 50.890  -63.977 26.327  1.00 77.67  ? 211 THR E CG2  1 
ATOM   6144  N  N    . GLY E 1 5   ? 47.757  -64.286 29.412  1.00 81.01  ? 212 GLY E N    1 
ATOM   6145  C  CA   . GLY E 1 5   ? 47.124  -64.124 30.735  1.00 75.21  ? 212 GLY E CA   1 
ATOM   6146  C  C    . GLY E 1 5   ? 48.005  -63.256 31.612  1.00 73.85  ? 212 GLY E C    1 
ATOM   6147  O  O    . GLY E 1 5   ? 47.618  -62.997 32.761  1.00 66.91  ? 212 GLY E O    1 
ATOM   6148  N  N    . TYR E 1 6   ? 49.141  -62.808 31.074  1.00 70.93  ? 213 TYR E N    1 
ATOM   6149  C  CA   . TYR E 1 6   ? 50.106  -62.000 31.855  1.00 71.14  ? 213 TYR E CA   1 
ATOM   6150  C  C    . TYR E 1 6   ? 50.125  -60.561 31.337  1.00 71.77  ? 213 TYR E C    1 
ATOM   6151  O  O    . TYR E 1 6   ? 50.227  -60.369 30.121  1.00 75.67  ? 213 TYR E O    1 
ATOM   6152  C  CB   . TYR E 1 6   ? 51.491  -62.641 31.790  1.00 68.88  ? 213 TYR E CB   1 
ATOM   6153  C  CG   . TYR E 1 6   ? 51.571  -64.107 32.126  1.00 64.55  ? 213 TYR E CG   1 
ATOM   6154  C  CD1  . TYR E 1 6   ? 51.169  -64.587 33.361  1.00 64.42  ? 213 TYR E CD1  1 
ATOM   6155  C  CD2  . TYR E 1 6   ? 52.084  -65.013 31.215  1.00 62.92  ? 213 TYR E CD2  1 
ATOM   6156  C  CE1  . TYR E 1 6   ? 51.258  -65.932 33.675  1.00 62.13  ? 213 TYR E CE1  1 
ATOM   6157  C  CE2  . TYR E 1 6   ? 52.175  -66.361 31.510  1.00 66.18  ? 213 TYR E CE2  1 
ATOM   6158  C  CZ   . TYR E 1 6   ? 51.763  -66.823 32.746  1.00 63.56  ? 213 TYR E CZ   1 
ATOM   6159  O  OH   . TYR E 1 6   ? 51.855  -68.151 33.039  1.00 63.25  ? 213 TYR E OH   1 
ATOM   6160  N  N    . VAL E 1 7   ? 50.021  -59.588 32.238  1.00 67.10  ? 214 VAL E N    1 
ATOM   6161  C  CA   . VAL E 1 7   ? 50.041  -58.170 31.887  1.00 73.06  ? 214 VAL E CA   1 
ATOM   6162  C  C    . VAL E 1 7   ? 51.474  -57.642 31.947  1.00 66.33  ? 214 VAL E C    1 
ATOM   6163  O  O    . VAL E 1 7   ? 52.247  -58.043 32.814  1.00 71.88  ? 214 VAL E O    1 
ATOM   6164  C  CB   . VAL E 1 7   ? 49.117  -57.388 32.841  1.00 70.37  ? 214 VAL E CB   1 
ATOM   6165  C  CG1  . VAL E 1 7   ? 49.372  -57.807 34.270  1.00 71.84  ? 214 VAL E CG1  1 
ATOM   6166  C  CG2  . VAL E 1 7   ? 49.342  -55.920 32.716  1.00 74.37  ? 214 VAL E CG2  1 
ATOM   6167  N  N    . GLY E 1 8   ? 51.835  -56.742 31.033  1.00 64.23  ? 215 GLY E N    1 
ATOM   6168  C  CA   . GLY E 1 8   ? 53.143  -56.115 31.023  1.00 61.45  ? 215 GLY E CA   1 
ATOM   6169  C  C    . GLY E 1 8   ? 53.220  -54.915 31.948  1.00 70.42  ? 215 GLY E C    1 
ATOM   6170  O  O    . GLY E 1 8   ? 52.359  -54.702 32.808  1.00 70.59  ? 215 GLY E O    1 
ATOM   6171  N  N    . LEU E 1 9   ? 54.276  -54.114 31.763  1.00 67.98  ? 216 LEU E N    1 
ATOM   6172  C  CA   . LEU E 1 9   ? 54.525  -52.936 32.592  1.00 66.32  ? 216 LEU E CA   1 
ATOM   6173  C  C    . LEU E 1 9   ? 54.821  -51.731 31.713  1.00 65.72  ? 216 LEU E C    1 
ATOM   6174  O  O    . LEU E 1 9   ? 55.441  -51.844 30.656  1.00 66.45  ? 216 LEU E O    1 
ATOM   6175  C  CB   . LEU E 1 9   ? 55.709  -53.129 33.553  1.00 59.86  ? 216 LEU E CB   1 
ATOM   6176  C  CG   . LEU E 1 9   ? 55.550  -54.064 34.753  1.00 65.66  ? 216 LEU E CG   1 
ATOM   6177  C  CD1  . LEU E 1 9   ? 56.893  -54.695 35.165  1.00 60.93  ? 216 LEU E CD1  1 
ATOM   6178  C  CD2  . LEU E 1 9   ? 54.887  -53.364 35.942  1.00 63.67  ? 216 LEU E CD2  1 
ATOM   6179  N  N    . LYS E 1 10  ? 54.413  -50.563 32.189  1.00 70.43  ? 217 LYS E N    1 
ATOM   6180  C  CA   . LYS E 1 10  ? 54.685  -49.330 31.468  1.00 68.87  ? 217 LYS E CA   1 
ATOM   6181  C  C    . LYS E 1 10  ? 56.186  -49.021 31.429  1.00 59.22  ? 217 LYS E C    1 
ATOM   6182  O  O    . LYS E 1 10  ? 56.970  -49.477 32.256  1.00 67.13  ? 217 LYS E O    1 
ATOM   6183  C  CB   . LYS E 1 10  ? 53.918  -48.181 32.115  1.00 63.79  ? 217 LYS E CB   1 
ATOM   6184  C  CG   . LYS E 1 10  ? 52.418  -48.389 32.090  1.00 66.94  ? 217 LYS E CG   1 
ATOM   6185  C  CD   . LYS E 1 10  ? 51.771  -47.622 33.222  1.00 71.12  ? 217 LYS E CD   1 
ATOM   6186  C  CE   . LYS E 1 10  ? 50.329  -47.245 32.959  1.00 64.95  ? 217 LYS E CE   1 
ATOM   6187  N  NZ   . LYS E 1 10  ? 49.956  -46.179 33.943  1.00 68.10  ? 217 LYS E NZ   1 
ATOM   6188  N  N    . ASN E 1 11  ? 56.586  -48.259 30.427  1.00 61.72  ? 218 ASN E N    1 
ATOM   6189  C  CA   . ASN E 1 11  ? 57.913  -47.670 30.380  1.00 62.38  ? 218 ASN E CA   1 
ATOM   6190  C  C    . ASN E 1 11  ? 57.785  -46.195 30.740  1.00 63.51  ? 218 ASN E C    1 
ATOM   6191  O  O    . ASN E 1 11  ? 57.285  -45.404 29.939  1.00 65.28  ? 218 ASN E O    1 
ATOM   6192  C  CB   . ASN E 1 11  ? 58.553  -47.823 29.006  1.00 59.48  ? 218 ASN E CB   1 
ATOM   6193  C  CG   . ASN E 1 11  ? 59.910  -47.112 28.923  1.00 66.77  ? 218 ASN E CG   1 
ATOM   6194  O  OD1  . ASN E 1 11  ? 60.425  -46.630 29.931  1.00 62.69  ? 218 ASN E OD1  1 
ATOM   6195  N  ND2  . ASN E 1 11  ? 60.493  -47.060 27.729  1.00 61.77  ? 218 ASN E ND2  1 
ATOM   6196  N  N    . GLN E 1 12  ? 58.319  -45.811 31.896  1.00 65.73  ? 219 GLN E N    1 
ATOM   6197  C  CA   . GLN E 1 12  ? 58.297  -44.393 32.336  1.00 61.59  ? 219 GLN E CA   1 
ATOM   6198  C  C    . GLN E 1 12  ? 59.159  -43.534 31.411  1.00 60.85  ? 219 GLN E C    1 
ATOM   6199  O  O    . GLN E 1 12  ? 58.909  -42.326 31.352  1.00 65.34  ? 219 GLN E O    1 
ATOM   6200  C  CB   . GLN E 1 12  ? 58.836  -44.306 33.758  1.00 52.95  ? 219 GLN E CB   1 
ATOM   6201  C  CG   . GLN E 1 12  ? 57.839  -44.741 34.814  1.00 51.31  ? 219 GLN E CG   1 
ATOM   6202  C  CD   . GLN E 1 12  ? 58.354  -44.437 36.196  1.00 67.78  ? 219 GLN E CD   1 
ATOM   6203  O  OE1  . GLN E 1 12  ? 58.594  -43.288 36.555  1.00 64.66  ? 219 GLN E OE1  1 
ATOM   6204  N  NE2  . GLN E 1 12  ? 58.535  -45.480 36.983  1.00 64.19  ? 219 GLN E NE2  1 
ATOM   6205  N  N    . GLY E 1 13  ? 60.136  -44.134 30.737  1.00 60.96  ? 220 GLY E N    1 
ATOM   6206  C  CA   . GLY E 1 13  ? 61.037  -43.419 29.815  1.00 61.71  ? 220 GLY E CA   1 
ATOM   6207  C  C    . GLY E 1 13  ? 62.210  -44.293 29.420  1.00 62.91  ? 220 GLY E C    1 
ATOM   6208  O  O    . GLY E 1 13  ? 62.447  -44.421 28.214  1.00 62.72  ? 220 GLY E O    1 
ATOM   6209  N  N    . ALA E 1 14  ? 62.885  -44.901 30.399  1.00 59.57  ? 221 ALA E N    1 
ATOM   6210  C  CA   . ALA E 1 14  ? 64.020  -45.813 30.133  1.00 56.98  ? 221 ALA E CA   1 
ATOM   6211  C  C    . ALA E 1 14  ? 64.014  -46.941 31.158  1.00 62.33  ? 221 ALA E C    1 
ATOM   6212  O  O    . ALA E 1 14  ? 65.079  -47.510 31.398  1.00 56.09  ? 221 ALA E O    1 
ATOM   6213  C  CB   . ALA E 1 14  ? 65.293  -45.043 30.215  1.00 52.27  ? 221 ALA E CB   1 
ATOM   6214  N  N    . THR E 1 15  ? 62.844  -47.278 31.689  1.00 59.59  ? 222 THR E N    1 
ATOM   6215  C  CA   . THR E 1 15  ? 62.735  -48.285 32.773  1.00 58.18  ? 222 THR E CA   1 
ATOM   6216  C  C    . THR E 1 15  ? 62.661  -49.705 32.205  1.00 57.18  ? 222 THR E C    1 
ATOM   6217  O  O    . THR E 1 15  ? 62.103  -50.558 32.893  1.00 58.93  ? 222 THR E O    1 
ATOM   6218  C  CB   . THR E 1 15  ? 61.557  -47.916 33.683  1.00 62.29  ? 222 THR E CB   1 
ATOM   6219  O  OG1  . THR E 1 15  ? 60.354  -47.863 32.917  1.00 68.25  ? 222 THR E OG1  1 
ATOM   6220  C  CG2  . THR E 1 15  ? 61.770  -46.596 34.389  1.00 55.22  ? 222 THR E CG2  1 
ATOM   6221  N  N    . CYS E 1 16  ? 63.224  -49.947 31.024  1.00 54.63  ? 223 CYS E N    1 
ATOM   6222  C  CA   . CYS E 1 16  ? 63.288  -51.304 30.421  1.00 52.98  ? 223 CYS E CA   1 
ATOM   6223  C  C    . CYS E 1 16  ? 63.878  -52.305 31.419  1.00 62.61  ? 223 CYS E C    1 
ATOM   6224  O  O    . CYS E 1 16  ? 63.275  -53.369 31.601  1.00 61.56  ? 223 CYS E O    1 
ATOM   6225  C  CB   . CYS E 1 16  ? 64.191  -51.283 29.193  1.00 50.59  ? 223 CYS E CB   1 
ATOM   6226  S  SG   . CYS E 1 16  ? 64.439  -49.646 28.458  1.00 78.76  ? 223 CYS E SG   1 
ATOM   6227  N  N    . TYR E 1 17  ? 65.019  -51.980 32.025  1.00 56.30  ? 224 TYR E N    1 
ATOM   6228  C  CA   . TYR E 1 17  ? 65.718  -52.849 33.005  1.00 56.69  ? 224 TYR E CA   1 
ATOM   6229  C  C    . TYR E 1 17  ? 64.810  -53.208 34.181  1.00 55.25  ? 224 TYR E C    1 
ATOM   6230  O  O    . TYR E 1 17  ? 64.785  -54.382 34.548  1.00 54.42  ? 224 TYR E O    1 
ATOM   6231  C  CB   . TYR E 1 17  ? 66.986  -52.127 33.476  1.00 58.31  ? 224 TYR E CB   1 
ATOM   6232  C  CG   . TYR E 1 17  ? 66.756  -50.817 34.191  1.00 55.64  ? 224 TYR E CG   1 
ATOM   6233  C  CD1  . TYR E 1 17  ? 66.506  -49.650 33.493  1.00 54.40  ? 224 TYR E CD1  1 
ATOM   6234  C  CD2  . TYR E 1 17  ? 66.770  -50.747 35.573  1.00 52.37  ? 224 TYR E CD2  1 
ATOM   6235  C  CE1  . TYR E 1 17  ? 66.269  -48.455 34.147  1.00 58.49  ? 224 TYR E CE1  1 
ATOM   6236  C  CE2  . TYR E 1 17  ? 66.524  -49.563 36.245  1.00 55.42  ? 224 TYR E CE2  1 
ATOM   6237  C  CZ   . TYR E 1 17  ? 66.276  -48.410 35.526  1.00 57.98  ? 224 TYR E CZ   1 
ATOM   6238  O  OH   . TYR E 1 17  ? 66.053  -47.230 36.167  1.00 56.73  ? 224 TYR E OH   1 
ATOM   6239  N  N    . MET E 1 18  ? 64.103  -52.235 34.749  1.00 47.37  ? 225 MET E N    1 
ATOM   6240  C  CA   . MET E 1 18  ? 63.255  -52.472 35.940  1.00 54.77  ? 225 MET E CA   1 
ATOM   6241  C  C    . MET E 1 18  ? 62.143  -53.439 35.581  1.00 56.62  ? 225 MET E C    1 
ATOM   6242  O  O    . MET E 1 18  ? 61.967  -54.416 36.298  1.00 54.04  ? 225 MET E O    1 
ATOM   6243  C  CB   . MET E 1 18  ? 62.621  -51.169 36.429  1.00 54.75  ? 225 MET E CB   1 
ATOM   6244  C  CG   . MET E 1 18  ? 62.275  -51.182 37.897  1.00 52.77  ? 225 MET E CG   1 
ATOM   6245  S  SD   . MET E 1 18  ? 61.967  -49.522 38.515  1.00 62.10  ? 225 MET E SD   1 
ATOM   6246  C  CE   . MET E 1 18  ? 60.816  -48.946 37.274  1.00 58.23  ? 225 MET E CE   1 
ATOM   6247  N  N    . ASN E 1 19  ? 61.452  -53.163 34.488  1.00 56.96  ? 226 ASN E N    1 
ATOM   6248  C  CA   . ASN E 1 19  ? 60.291  -53.993 34.104  1.00 61.64  ? 226 ASN E CA   1 
ATOM   6249  C  C    . ASN E 1 19  ? 60.746  -55.450 33.949  1.00 59.21  ? 226 ASN E C    1 
ATOM   6250  O  O    . ASN E 1 19  ? 60.059  -56.326 34.471  1.00 58.09  ? 226 ASN E O    1 
ATOM   6251  C  CB   . ASN E 1 19  ? 59.584  -53.352 32.909  1.00 56.04  ? 226 ASN E CB   1 
ATOM   6252  C  CG   . ASN E 1 19  ? 59.156  -51.929 33.190  1.00 56.92  ? 226 ASN E CG   1 
ATOM   6253  O  OD1  . ASN E 1 19  ? 58.803  -51.591 34.314  1.00 61.82  ? 226 ASN E OD1  1 
ATOM   6254  N  ND2  . ASN E 1 19  ? 59.199  -51.083 32.179  1.00 62.38  ? 226 ASN E ND2  1 
ATOM   6255  N  N    . SER E 1 20  ? 61.898  -55.677 33.328  1.00 59.36  ? 227 SER E N    1 
ATOM   6256  C  CA   . SER E 1 20  ? 62.370  -57.061 33.068  1.00 58.01  ? 227 SER E CA   1 
ATOM   6257  C  C    . SER E 1 20  ? 62.722  -57.766 34.382  1.00 58.27  ? 227 SER E C    1 
ATOM   6258  O  O    . SER E 1 20  ? 62.447  -58.962 34.481  1.00 57.65  ? 227 SER E O    1 
ATOM   6259  C  CB   . SER E 1 20  ? 63.517  -57.057 32.090  1.00 54.32  ? 227 SER E CB   1 
ATOM   6260  O  OG   . SER E 1 20  ? 63.193  -56.323 30.921  1.00 53.07  ? 227 SER E OG   1 
ATOM   6261  N  N    . LEU E 1 21  ? 63.285  -57.044 35.348  1.00 53.76  ? 228 LEU E N    1 
ATOM   6262  C  CA   . LEU E 1 21  ? 63.635  -57.625 36.665  1.00 52.39  ? 228 LEU E CA   1 
ATOM   6263  C  C    . LEU E 1 21  ? 62.351  -57.883 37.447  1.00 53.91  ? 228 LEU E C    1 
ATOM   6264  O  O    . LEU E 1 21  ? 62.266  -58.924 38.088  1.00 59.39  ? 228 LEU E O    1 
ATOM   6265  C  CB   . LEU E 1 21  ? 64.526  -56.626 37.408  1.00 52.78  ? 228 LEU E CB   1 
ATOM   6266  C  CG   . LEU E 1 21  ? 65.567  -57.174 38.380  1.00 51.03  ? 228 LEU E CG   1 
ATOM   6267  C  CD1  . LEU E 1 21  ? 65.216  -56.790 39.803  1.00 52.18  ? 228 LEU E CD1  1 
ATOM   6268  C  CD2  . LEU E 1 21  ? 65.744  -58.677 38.247  1.00 48.91  ? 228 LEU E CD2  1 
ATOM   6269  N  N    . LEU E 1 22  ? 61.398  -56.964 37.389  1.00 52.57  ? 229 LEU E N    1 
ATOM   6270  C  CA   . LEU E 1 22  ? 60.156  -57.092 38.186  1.00 51.91  ? 229 LEU E CA   1 
ATOM   6271  C  C    . LEU E 1 22  ? 59.370  -58.331 37.757  1.00 59.38  ? 229 LEU E C    1 
ATOM   6272  O  O    . LEU E 1 22  ? 58.880  -59.028 38.637  1.00 56.40  ? 229 LEU E O    1 
ATOM   6273  C  CB   . LEU E 1 22  ? 59.328  -55.821 38.003  1.00 52.10  ? 229 LEU E CB   1 
ATOM   6274  C  CG   . LEU E 1 22  ? 59.686  -54.670 38.934  1.00 57.65  ? 229 LEU E CG   1 
ATOM   6275  C  CD1  . LEU E 1 22  ? 59.124  -53.368 38.397  1.00 54.86  ? 229 LEU E CD1  1 
ATOM   6276  C  CD2  . LEU E 1 22  ? 59.171  -54.940 40.336  1.00 48.41  ? 229 LEU E CD2  1 
ATOM   6277  N  N    . GLN E 1 23  ? 59.272  -58.585 36.459  1.00 53.49  ? 230 GLN E N    1 
ATOM   6278  C  CA   . GLN E 1 23  ? 58.553  -59.777 35.968  1.00 55.05  ? 230 GLN E CA   1 
ATOM   6279  C  C    . GLN E 1 23  ? 59.294  -61.029 36.433  1.00 57.90  ? 230 GLN E C    1 
ATOM   6280  O  O    . GLN E 1 23  ? 58.641  -61.921 36.952  1.00 58.55  ? 230 GLN E O    1 
ATOM   6281  C  CB   . GLN E 1 23  ? 58.407  -59.717 34.451  1.00 61.77  ? 230 GLN E CB   1 
ATOM   6282  C  CG   . GLN E 1 23  ? 57.664  -58.489 33.952  1.00 61.66  ? 230 GLN E CG   1 
ATOM   6283  C  CD   . GLN E 1 23  ? 56.167  -58.653 33.898  1.00 62.97  ? 230 GLN E CD   1 
ATOM   6284  O  OE1  . GLN E 1 23  ? 55.602  -59.626 34.389  1.00 60.94  ? 230 GLN E OE1  1 
ATOM   6285  N  NE2  . GLN E 1 23  ? 55.506  -57.686 33.288  1.00 61.83  ? 230 GLN E NE2  1 
ATOM   6286  N  N    . THR E 1 24  ? 60.611  -61.065 36.284  1.00 57.77  ? 231 THR E N    1 
ATOM   6287  C  CA   . THR E 1 24  ? 61.426  -62.217 36.744  1.00 55.07  ? 231 THR E CA   1 
ATOM   6288  C  C    . THR E 1 24  ? 61.161  -62.480 38.228  1.00 55.20  ? 231 THR E C    1 
ATOM   6289  O  O    . THR E 1 24  ? 60.931  -63.643 38.581  1.00 57.55  ? 231 THR E O    1 
ATOM   6290  C  CB   . THR E 1 24  ? 62.909  -61.958 36.457  1.00 55.12  ? 231 THR E CB   1 
ATOM   6291  O  OG1  . THR E 1 24  ? 63.055  -61.666 35.069  1.00 54.89  ? 231 THR E OG1  1 
ATOM   6292  C  CG2  . THR E 1 24  ? 63.803  -63.119 36.827  1.00 48.80  ? 231 THR E CG2  1 
ATOM   6293  N  N    . LEU E 1 25  ? 61.141  -61.436 39.050  1.00 55.59  ? 232 LEU E N    1 
ATOM   6294  C  CA   . LEU E 1 25  ? 60.978  -61.606 40.514  1.00 55.43  ? 232 LEU E CA   1 
ATOM   6295  C  C    . LEU E 1 25  ? 59.521  -61.908 40.859  1.00 59.96  ? 232 LEU E C    1 
ATOM   6296  O  O    . LEU E 1 25  ? 59.298  -62.598 41.860  1.00 58.40  ? 232 LEU E O    1 
ATOM   6297  C  CB   . LEU E 1 25  ? 61.458  -60.326 41.196  1.00 49.54  ? 232 LEU E CB   1 
ATOM   6298  C  CG   . LEU E 1 25  ? 62.965  -60.096 41.185  1.00 58.60  ? 232 LEU E CG   1 
ATOM   6299  C  CD1  . LEU E 1 25  ? 63.336  -59.019 42.182  1.00 45.78  ? 232 LEU E CD1  1 
ATOM   6300  C  CD2  . LEU E 1 25  ? 63.725  -61.378 41.480  1.00 42.12  ? 232 LEU E CD2  1 
ATOM   6301  N  N    . PHE E 1 26  ? 58.575  -61.403 40.071  1.00 59.01  ? 233 PHE E N    1 
ATOM   6302  C  CA   . PHE E 1 26  ? 57.140  -61.704 40.285  1.00 62.18  ? 233 PHE E CA   1 
ATOM   6303  C  C    . PHE E 1 26  ? 56.914  -63.192 40.042  1.00 62.64  ? 233 PHE E C    1 
ATOM   6304  O  O    . PHE E 1 26  ? 56.152  -63.799 40.798  1.00 63.79  ? 233 PHE E O    1 
ATOM   6305  C  CB   . PHE E 1 26  ? 56.295  -60.851 39.340  1.00 65.60  ? 233 PHE E CB   1 
ATOM   6306  C  CG   . PHE E 1 26  ? 54.818  -61.134 39.306  1.00 65.63  ? 233 PHE E CG   1 
ATOM   6307  C  CD1  . PHE E 1 26  ? 54.007  -60.812 40.379  1.00 65.82  ? 233 PHE E CD1  1 
ATOM   6308  C  CD2  . PHE E 1 26  ? 54.234  -61.687 38.181  1.00 63.02  ? 233 PHE E CD2  1 
ATOM   6309  C  CE1  . PHE E 1 26  ? 52.646  -61.063 40.334  1.00 64.30  ? 233 PHE E CE1  1 
ATOM   6310  C  CE2  . PHE E 1 26  ? 52.873  -61.939 38.139  1.00 64.08  ? 233 PHE E CE2  1 
ATOM   6311  C  CZ   . PHE E 1 26  ? 52.082  -61.630 39.218  1.00 59.22  ? 233 PHE E CZ   1 
ATOM   6312  N  N    . PHE E 1 27  ? 57.595  -63.755 39.042  1.00 59.91  ? 234 PHE E N    1 
ATOM   6313  C  CA   . PHE E 1 27  ? 57.394  -65.183 38.691  1.00 60.61  ? 234 PHE E CA   1 
ATOM   6314  C  C    . PHE E 1 27  ? 58.217  -66.063 39.624  1.00 63.46  ? 234 PHE E C    1 
ATOM   6315  O  O    . PHE E 1 27  ? 58.114  -67.277 39.490  1.00 62.25  ? 234 PHE E O    1 
ATOM   6316  C  CB   . PHE E 1 27  ? 57.601  -65.394 37.192  1.00 61.66  ? 234 PHE E CB   1 
ATOM   6317  C  CG   . PHE E 1 27  ? 56.500  -64.770 36.376  1.00 64.25  ? 234 PHE E CG   1 
ATOM   6318  C  CD1  . PHE E 1 27  ? 55.174  -65.064 36.639  1.00 64.01  ? 234 PHE E CD1  1 
ATOM   6319  C  CD2  . PHE E 1 27  ? 56.784  -63.861 35.374  1.00 61.91  ? 234 PHE E CD2  1 
ATOM   6320  C  CE1  . PHE E 1 27  ? 54.158  -64.485 35.898  1.00 65.64  ? 234 PHE E CE1  1 
ATOM   6321  C  CE2  . PHE E 1 27  ? 55.767  -63.265 34.650  1.00 62.67  ? 234 PHE E CE2  1 
ATOM   6322  C  CZ   . PHE E 1 27  ? 54.457  -63.583 34.907  1.00 64.14  ? 234 PHE E CZ   1 
ATOM   6323  N  N    . THR E 1 28  ? 59.029  -65.476 40.499  1.00 61.41  ? 235 THR E N    1 
ATOM   6324  C  CA   . THR E 1 28  ? 59.680  -66.273 41.566  1.00 63.79  ? 235 THR E CA   1 
ATOM   6325  C  C    . THR E 1 28  ? 58.584  -66.302 42.630  1.00 68.25  ? 235 THR E C    1 
ATOM   6326  O  O    . THR E 1 28  ? 58.645  -65.486 43.556  1.00 62.61  ? 235 THR E O    1 
ATOM   6327  C  CB   . THR E 1 28  ? 61.046  -65.699 41.953  1.00 61.49  ? 235 THR E CB   1 
ATOM   6328  O  OG1  . THR E 1 28  ? 61.815  -65.526 40.764  1.00 54.57  ? 235 THR E OG1  1 
ATOM   6329  C  CG2  . THR E 1 28  ? 61.802  -66.587 42.914  1.00 56.74  ? 235 THR E CG2  1 
ATOM   6330  N  N    . ASN E 1 29  ? 57.594  -67.180 42.470  1.00 70.83  ? 236 ASN E N    1 
ATOM   6331  C  CA   . ASN E 1 29  ? 56.374  -67.196 43.322  1.00 62.67  ? 236 ASN E CA   1 
ATOM   6332  C  C    . ASN E 1 29  ? 56.673  -67.150 44.821  1.00 63.15  ? 236 ASN E C    1 
ATOM   6333  O  O    . ASN E 1 29  ? 55.964  -66.423 45.520  1.00 67.61  ? 236 ASN E O    1 
ATOM   6334  C  CB   . ASN E 1 29  ? 55.494  -68.378 42.912  1.00 67.31  ? 236 ASN E CB   1 
ATOM   6335  C  CG   . ASN E 1 29  ? 54.940  -68.250 41.508  1.00 71.89  ? 236 ASN E CG   1 
ATOM   6336  O  OD1  . ASN E 1 29  ? 55.241  -67.297 40.796  1.00 66.88  ? 236 ASN E OD1  1 
ATOM   6337  N  ND2  . ASN E 1 29  ? 54.123  -69.204 41.098  1.00 65.68  ? 236 ASN E ND2  1 
ATOM   6338  N  N    . GLN E 1 30  ? 57.654  -67.906 45.294  1.00 56.38  ? 237 GLN E N    1 
ATOM   6339  C  CA   . GLN E 1 30  ? 57.934  -67.957 46.745  1.00 60.36  ? 237 GLN E CA   1 
ATOM   6340  C  C    . GLN E 1 30  ? 58.291  -66.554 47.241  1.00 62.42  ? 237 GLN E C    1 
ATOM   6341  O  O    . GLN E 1 30  ? 57.873  -66.216 48.353  1.00 57.14  ? 237 GLN E O    1 
ATOM   6342  C  CB   . GLN E 1 30  ? 59.050  -68.962 46.999  1.00 60.91  ? 237 GLN E CB   1 
ATOM   6343  C  CG   . GLN E 1 30  ? 58.627  -70.171 47.810  1.00 61.36  ? 237 GLN E CG   1 
ATOM   6344  C  CD   . GLN E 1 30  ? 59.828  -70.961 48.258  1.00 65.88  ? 237 GLN E CD   1 
ATOM   6345  O  OE1  . GLN E 1 30  ? 60.441  -71.690 47.484  1.00 62.22  ? 237 GLN E OE1  1 
ATOM   6346  N  NE2  . GLN E 1 30  ? 60.180  -70.816 49.523  1.00 68.53  ? 237 GLN E NE2  1 
ATOM   6347  N  N    . LEU E 1 31  ? 59.017  -65.776 46.435  1.00 58.59  ? 238 LEU E N    1 
ATOM   6348  C  CA   . LEU E 1 31  ? 59.401  -64.390 46.808  1.00 62.51  ? 238 LEU E CA   1 
ATOM   6349  C  C    . LEU E 1 31  ? 58.156  -63.512 46.810  1.00 63.38  ? 238 LEU E C    1 
ATOM   6350  O  O    . LEU E 1 31  ? 57.991  -62.746 47.755  1.00 66.16  ? 238 LEU E O    1 
ATOM   6351  C  CB   . LEU E 1 31  ? 60.432  -63.863 45.807  1.00 58.29  ? 238 LEU E CB   1 
ATOM   6352  C  CG   . LEU E 1 31  ? 60.970  -62.461 46.071  1.00 54.91  ? 238 LEU E CG   1 
ATOM   6353  C  CD1  . LEU E 1 31  ? 61.731  -62.417 47.383  1.00 56.40  ? 238 LEU E CD1  1 
ATOM   6354  C  CD2  . LEU E 1 31  ? 61.858  -62.013 44.927  1.00 56.66  ? 238 LEU E CD2  1 
ATOM   6355  N  N    . ARG E 1 32  ? 57.322  -63.637 45.785  1.00 61.72  ? 239 ARG E N    1 
ATOM   6356  C  CA   . ARG E 1 32  ? 56.103  -62.807 45.675  1.00 62.76  ? 239 ARG E CA   1 
ATOM   6357  C  C    . ARG E 1 32  ? 55.237  -63.016 46.916  1.00 63.14  ? 239 ARG E C    1 
ATOM   6358  O  O    . ARG E 1 32  ? 54.771  -62.016 47.468  1.00 63.51  ? 239 ARG E O    1 
ATOM   6359  C  CB   . ARG E 1 32  ? 55.380  -63.178 44.381  1.00 64.47  ? 239 ARG E CB   1 
ATOM   6360  C  CG   . ARG E 1 32  ? 54.186  -62.305 44.035  1.00 63.75  ? 239 ARG E CG   1 
ATOM   6361  C  CD   . ARG E 1 32  ? 53.127  -63.148 43.360  1.00 62.72  ? 239 ARG E CD   1 
ATOM   6362  N  NE   . ARG E 1 32  ? 53.627  -63.834 42.181  1.00 62.43  ? 239 ARG E NE   1 
ATOM   6363  C  CZ   . ARG E 1 32  ? 52.869  -64.465 41.297  1.00 60.85  ? 239 ARG E CZ   1 
ATOM   6364  N  NH1  . ARG E 1 32  ? 51.557  -64.499 41.448  1.00 67.99  ? 239 ARG E NH1  1 
ATOM   6365  N  NH2  . ARG E 1 32  ? 53.423  -65.048 40.252  1.00 62.18  ? 239 ARG E NH2  1 
ATOM   6366  N  N    . LYS E 1 33  ? 55.061  -64.266 47.344  1.00 64.08  ? 240 LYS E N    1 
ATOM   6367  C  CA   . LYS E 1 33  ? 54.214  -64.578 48.523  1.00 63.53  ? 240 LYS E CA   1 
ATOM   6368  C  C    . LYS E 1 33  ? 54.803  -63.905 49.760  1.00 61.64  ? 240 LYS E C    1 
ATOM   6369  O  O    . LYS E 1 33  ? 54.039  -63.304 50.512  1.00 61.61  ? 240 LYS E O    1 
ATOM   6370  C  CB   . LYS E 1 33  ? 54.109  -66.093 48.704  1.00 60.16  ? 240 LYS E CB   1 
ATOM   6371  C  CG   . LYS E 1 33  ? 52.900  -66.573 49.492  1.00 68.07  ? 240 LYS E CG   1 
ATOM   6372  N  N    . ALA E 1 34  ? 56.113  -64.016 49.953  1.00 63.37  ? 241 ALA E N    1 
ATOM   6373  C  CA   . ALA E 1 34  ? 56.783  -63.379 51.108  1.00 63.82  ? 241 ALA E CA   1 
ATOM   6374  C  C    . ALA E 1 34  ? 56.649  -61.856 51.053  1.00 60.30  ? 241 ALA E C    1 
ATOM   6375  O  O    . ALA E 1 34  ? 56.398  -61.270 52.105  1.00 60.62  ? 241 ALA E O    1 
ATOM   6376  C  CB   . ALA E 1 34  ? 58.222  -63.788 51.118  1.00 60.33  ? 241 ALA E CB   1 
ATOM   6377  N  N    . VAL E 1 35  ? 56.809  -61.252 49.875  1.00 56.33  ? 242 VAL E N    1 
ATOM   6378  C  CA   . VAL E 1 35  ? 56.645  -59.776 49.715  1.00 64.96  ? 242 VAL E CA   1 
ATOM   6379  C  C    . VAL E 1 35  ? 55.223  -59.396 50.133  1.00 62.96  ? 242 VAL E C    1 
ATOM   6380  O  O    . VAL E 1 35  ? 55.056  -58.348 50.773  1.00 62.88  ? 242 VAL E O    1 
ATOM   6381  C  CB   . VAL E 1 35  ? 56.990  -59.315 48.284  1.00 68.52  ? 242 VAL E CB   1 
ATOM   6382  C  CG1  . VAL E 1 35  ? 56.523  -57.899 47.986  1.00 63.17  ? 242 VAL E CG1  1 
ATOM   6383  C  CG2  . VAL E 1 35  ? 58.477  -59.442 48.000  1.00 63.68  ? 242 VAL E CG2  1 
ATOM   6384  N  N    . TYR E 1 36  ? 54.248  -60.249 49.828  1.00 65.23  ? 243 TYR E N    1 
ATOM   6385  C  CA   . TYR E 1 36  ? 52.848  -59.997 50.243  1.00 63.74  ? 243 TYR E CA   1 
ATOM   6386  C  C    . TYR E 1 36  ? 52.734  -60.021 51.768  1.00 66.19  ? 243 TYR E C    1 
ATOM   6387  O  O    . TYR E 1 36  ? 52.014  -59.179 52.313  1.00 60.72  ? 243 TYR E O    1 
ATOM   6388  C  CB   . TYR E 1 36  ? 51.919  -61.039 49.625  1.00 62.23  ? 243 TYR E CB   1 
ATOM   6389  C  CG   . TYR E 1 36  ? 51.627  -60.862 48.159  1.00 69.07  ? 243 TYR E CG   1 
ATOM   6390  C  CD1  . TYR E 1 36  ? 51.560  -59.604 47.582  1.00 65.70  ? 243 TYR E CD1  1 
ATOM   6391  C  CD2  . TYR E 1 36  ? 51.406  -61.960 47.349  1.00 66.66  ? 243 TYR E CD2  1 
ATOM   6392  C  CE1  . TYR E 1 36  ? 51.286  -59.442 46.235  1.00 63.90  ? 243 TYR E CE1  1 
ATOM   6393  C  CE2  . TYR E 1 36  ? 51.128  -61.815 46.002  1.00 69.22  ? 243 TYR E CE2  1 
ATOM   6394  C  CZ   . TYR E 1 36  ? 51.069  -60.553 45.442  1.00 63.75  ? 243 TYR E CZ   1 
ATOM   6395  O  OH   . TYR E 1 36  ? 50.797  -60.418 44.114  1.00 71.50  ? 243 TYR E OH   1 
ATOM   6396  N  N    . MET E 1 37  ? 53.447  -60.929 52.433  1.00 65.27  ? 244 MET E N    1 
ATOM   6397  C  CA   . MET E 1 37  ? 53.294  -61.079 53.901  1.00 64.03  ? 244 MET E CA   1 
ATOM   6398  C  C    . MET E 1 37  ? 54.280  -60.182 54.649  1.00 69.92  ? 244 MET E C    1 
ATOM   6399  O  O    . MET E 1 37  ? 54.354  -60.308 55.876  1.00 76.47  ? 244 MET E O    1 
ATOM   6400  C  CB   . MET E 1 37  ? 53.487  -62.541 54.303  1.00 64.88  ? 244 MET E CB   1 
ATOM   6401  C  CG   . MET E 1 37  ? 52.306  -63.414 53.938  1.00 72.07  ? 244 MET E CG   1 
ATOM   6402  S  SD   . MET E 1 37  ? 52.792  -65.113 53.561  1.00 95.67  ? 244 MET E SD   1 
ATOM   6403  C  CE   . MET E 1 37  ? 53.597  -65.576 55.093  1.00 68.16  ? 244 MET E CE   1 
ATOM   6404  N  N    . MET E 1 38  ? 54.988  -59.299 53.945  1.00 74.31  ? 245 MET E N    1 
ATOM   6405  C  CA   . MET E 1 38  ? 55.889  -58.328 54.614  1.00 73.74  ? 245 MET E CA   1 
ATOM   6406  C  C    . MET E 1 38  ? 55.029  -57.312 55.361  1.00 75.88  ? 245 MET E C    1 
ATOM   6407  O  O    . MET E 1 38  ? 54.066  -56.801 54.769  1.00 71.46  ? 245 MET E O    1 
ATOM   6408  C  CB   . MET E 1 38  ? 56.748  -57.577 53.600  1.00 67.62  ? 245 MET E CB   1 
ATOM   6409  C  CG   . MET E 1 38  ? 57.932  -58.355 53.100  1.00 70.70  ? 245 MET E CG   1 
ATOM   6410  S  SD   . MET E 1 38  ? 58.958  -57.300 52.063  1.00 67.01  ? 245 MET E SD   1 
ATOM   6411  C  CE   . MET E 1 38  ? 59.895  -56.452 53.330  1.00 56.69  ? 245 MET E CE   1 
ATOM   6412  N  N    . PRO E 1 39  ? 55.324  -57.024 56.641  1.00 79.30  ? 246 PRO E N    1 
ATOM   6413  C  CA   . PRO E 1 39  ? 54.573  -56.024 57.392  1.00 80.81  ? 246 PRO E CA   1 
ATOM   6414  C  C    . PRO E 1 39  ? 54.781  -54.610 56.829  1.00 83.54  ? 246 PRO E C    1 
ATOM   6415  O  O    . PRO E 1 39  ? 55.784  -53.998 57.122  1.00 82.31  ? 246 PRO E O    1 
ATOM   6416  C  CB   . PRO E 1 39  ? 55.093  -56.177 58.827  1.00 72.33  ? 246 PRO E CB   1 
ATOM   6417  C  CG   . PRO E 1 39  ? 56.431  -56.845 58.686  1.00 81.68  ? 246 PRO E CG   1 
ATOM   6418  C  CD   . PRO E 1 39  ? 56.336  -57.697 57.441  1.00 76.21  ? 246 PRO E CD   1 
ATOM   6419  N  N    . THR E 1 40  ? 53.815  -54.130 56.047  1.00 85.99  ? 247 THR E N    1 
ATOM   6420  C  CA   . THR E 1 40  ? 53.915  -52.790 55.419  1.00 83.72  ? 247 THR E CA   1 
ATOM   6421  C  C    . THR E 1 40  ? 52.698  -51.954 55.817  1.00 89.38  ? 247 THR E C    1 
ATOM   6422  O  O    . THR E 1 40  ? 52.538  -50.849 55.276  1.00 93.73  ? 247 THR E O    1 
ATOM   6423  C  CB   . THR E 1 40  ? 54.035  -52.936 53.899  1.00 82.53  ? 247 THR E CB   1 
ATOM   6424  O  OG1  . THR E 1 40  ? 54.277  -51.644 53.345  1.00 87.18  ? 247 THR E OG1  1 
ATOM   6425  C  CG2  . THR E 1 40  ? 52.814  -53.559 53.258  1.00 76.51  ? 247 THR E CG2  1 
ATOM   6426  N  N    . GLU E 1 41  ? 51.870  -52.463 56.725  1.00 87.27  ? 248 GLU E N    1 
ATOM   6427  C  CA   . GLU E 1 41  ? 50.639  -51.738 57.123  1.00 93.20  ? 248 GLU E CA   1 
ATOM   6428  C  C    . GLU E 1 41  ? 51.015  -50.340 57.612  1.00 97.62  ? 248 GLU E C    1 
ATOM   6429  O  O    . GLU E 1 41  ? 50.221  -49.411 57.383  1.00 93.01  ? 248 GLU E O    1 
ATOM   6430  N  N    . GLY E 1 42  ? 52.200  -50.193 58.216  1.00 101.68 ? 249 GLY E N    1 
ATOM   6431  C  CA   . GLY E 1 42  ? 52.638  -48.898 58.776  1.00 96.02  ? 249 GLY E CA   1 
ATOM   6432  C  C    . GLY E 1 42  ? 52.999  -47.873 57.719  1.00 96.87  ? 249 GLY E C    1 
ATOM   6433  O  O    . GLY E 1 42  ? 53.578  -46.841 58.091  1.00 104.75 ? 249 GLY E O    1 
ATOM   6434  N  N    . ASP E 1 43  ? 52.672  -48.137 56.455  1.00 98.38  ? 250 ASP E N    1 
ATOM   6435  C  CA   . ASP E 1 43  ? 52.939  -47.178 55.356  1.00 98.08  ? 250 ASP E CA   1 
ATOM   6436  C  C    . ASP E 1 43  ? 51.634  -46.935 54.591  1.00 95.86  ? 250 ASP E C    1 
ATOM   6437  O  O    . ASP E 1 43  ? 50.609  -46.704 55.263  1.00 97.62  ? 250 ASP E O    1 
ATOM   6438  C  CB   . ASP E 1 43  ? 54.071  -47.688 54.463  1.00 91.23  ? 250 ASP E CB   1 
ATOM   6439  N  N    . SER E 1 45  ? 52.523  -45.985 50.570  1.00 86.79  ? 252 SER E N    1 
ATOM   6440  C  CA   . SER E 1 45  ? 52.516  -45.238 49.288  1.00 84.12  ? 252 SER E CA   1 
ATOM   6441  C  C    . SER E 1 45  ? 53.908  -45.319 48.665  1.00 88.22  ? 252 SER E C    1 
ATOM   6442  O  O    . SER E 1 45  ? 54.264  -46.396 48.158  1.00 85.07  ? 252 SER E O    1 
ATOM   6443  C  CB   . SER E 1 45  ? 52.095  -43.809 49.518  1.00 80.67  ? 252 SER E CB   1 
ATOM   6444  O  OG   . SER E 1 45  ? 50.861  -43.745 50.217  1.00 80.70  ? 252 SER E OG   1 
ATOM   6445  N  N    . SER E 1 46  ? 54.651  -44.216 48.693  1.00 87.93  ? 253 SER E N    1 
ATOM   6446  C  CA   . SER E 1 46  ? 56.056  -44.221 48.216  1.00 85.02  ? 253 SER E CA   1 
ATOM   6447  C  C    . SER E 1 46  ? 56.953  -44.382 49.440  1.00 84.40  ? 253 SER E C    1 
ATOM   6448  O  O    . SER E 1 46  ? 58.179  -44.399 49.282  1.00 76.23  ? 253 SER E O    1 
ATOM   6449  C  CB   . SER E 1 46  ? 56.334  -42.955 47.483  1.00 75.79  ? 253 SER E CB   1 
ATOM   6450  O  OG   . SER E 1 46  ? 57.721  -42.763 47.275  1.00 81.73  ? 253 SER E OG   1 
ATOM   6451  N  N    . LYS E 1 47  ? 56.345  -44.536 50.615  1.00 83.94  ? 254 LYS E N    1 
ATOM   6452  C  CA   . LYS E 1 47  ? 57.106  -44.651 51.880  1.00 79.06  ? 254 LYS E CA   1 
ATOM   6453  C  C    . LYS E 1 47  ? 58.194  -45.713 51.765  1.00 81.71  ? 254 LYS E C    1 
ATOM   6454  O  O    . LYS E 1 47  ? 59.275  -45.477 52.327  1.00 84.80  ? 254 LYS E O    1 
ATOM   6455  N  N    . SER E 1 48  ? 57.933  -46.808 51.052  1.00 76.65  ? 255 SER E N    1 
ATOM   6456  C  CA   . SER E 1 48  ? 58.940  -47.897 51.058  1.00 76.78  ? 255 SER E CA   1 
ATOM   6457  C  C    . SER E 1 48  ? 58.942  -48.733 49.786  1.00 72.26  ? 255 SER E C    1 
ATOM   6458  O  O    . SER E 1 48  ? 57.880  -48.876 49.165  1.00 70.95  ? 255 SER E O    1 
ATOM   6459  C  CB   . SER E 1 48  ? 58.745  -48.791 52.253  1.00 70.35  ? 255 SER E CB   1 
ATOM   6460  O  OG   . SER E 1 48  ? 57.403  -49.234 52.356  1.00 81.87  ? 255 SER E OG   1 
ATOM   6461  N  N    . VAL E 1 49  ? 60.110  -49.268 49.444  1.00 65.16  ? 256 VAL E N    1 
ATOM   6462  C  CA   . VAL E 1 49  ? 60.216  -50.212 48.299  1.00 65.07  ? 256 VAL E CA   1 
ATOM   6463  C  C    . VAL E 1 49  ? 59.329  -51.419 48.601  1.00 68.00  ? 256 VAL E C    1 
ATOM   6464  O  O    . VAL E 1 49  ? 58.596  -51.800 47.699  1.00 61.61  ? 256 VAL E O    1 
ATOM   6465  C  CB   . VAL E 1 49  ? 61.680  -50.606 48.029  1.00 64.94  ? 256 VAL E CB   1 
ATOM   6466  C  CG1  . VAL E 1 49  ? 61.811  -51.516 46.825  1.00 61.83  ? 256 VAL E CG1  1 
ATOM   6467  C  CG2  . VAL E 1 49  ? 62.577  -49.390 47.885  1.00 58.40  ? 256 VAL E CG2  1 
ATOM   6468  N  N    . PRO E 1 50  ? 59.358  -52.057 49.794  1.00 66.07  ? 257 PRO E N    1 
ATOM   6469  C  CA   . PRO E 1 50  ? 58.416  -53.129 50.101  1.00 64.12  ? 257 PRO E CA   1 
ATOM   6470  C  C    . PRO E 1 50  ? 56.967  -52.785 49.726  1.00 67.11  ? 257 PRO E C    1 
ATOM   6471  O  O    . PRO E 1 50  ? 56.358  -53.556 49.030  1.00 60.68  ? 257 PRO E O    1 
ATOM   6472  C  CB   . PRO E 1 50  ? 58.579  -53.258 51.615  1.00 67.26  ? 257 PRO E CB   1 
ATOM   6473  C  CG   . PRO E 1 50  ? 60.043  -53.062 51.824  1.00 59.87  ? 257 PRO E CG   1 
ATOM   6474  C  CD   . PRO E 1 50  ? 60.366  -51.943 50.866  1.00 67.14  ? 257 PRO E CD   1 
ATOM   6475  N  N    . LEU E 1 51  ? 56.461  -51.644 50.192  1.00 69.08  ? 258 LEU E N    1 
ATOM   6476  C  CA   . LEU E 1 51  ? 55.071  -51.229 49.886  1.00 69.17  ? 258 LEU E CA   1 
ATOM   6477  C  C    . LEU E 1 51  ? 54.888  -51.138 48.377  1.00 67.26  ? 258 LEU E C    1 
ATOM   6478  O  O    . LEU E 1 51  ? 53.884  -51.654 47.873  1.00 69.68  ? 258 LEU E O    1 
ATOM   6479  C  CB   . LEU E 1 51  ? 54.806  -49.869 50.529  1.00 79.08  ? 258 LEU E CB   1 
ATOM   6480  N  N    . ALA E 1 52  ? 55.830  -50.501 47.699  1.00 65.19  ? 259 ALA E N    1 
ATOM   6481  C  CA   . ALA E 1 52  ? 55.732  -50.326 46.239  1.00 63.01  ? 259 ALA E CA   1 
ATOM   6482  C  C    . ALA E 1 52  ? 55.780  -51.676 45.528  1.00 66.08  ? 259 ALA E C    1 
ATOM   6483  O  O    . ALA E 1 52  ? 54.974  -51.878 44.617  1.00 66.92  ? 259 ALA E O    1 
ATOM   6484  C  CB   . ALA E 1 52  ? 56.856  -49.441 45.808  1.00 64.76  ? 259 ALA E CB   1 
ATOM   6485  N  N    . LEU E 1 53  ? 56.688  -52.555 45.943  1.00 66.48  ? 260 LEU E N    1 
ATOM   6486  C  CA   . LEU E 1 53  ? 56.845  -53.876 45.291  1.00 65.21  ? 260 LEU E CA   1 
ATOM   6487  C  C    . LEU E 1 53  ? 55.569  -54.679 45.516  1.00 67.29  ? 260 LEU E C    1 
ATOM   6488  O  O    . LEU E 1 53  ? 55.204  -55.456 44.637  1.00 62.11  ? 260 LEU E O    1 
ATOM   6489  C  CB   . LEU E 1 53  ? 58.061  -54.578 45.895  1.00 62.40  ? 260 LEU E CB   1 
ATOM   6490  C  CG   . LEU E 1 53  ? 58.939  -55.334 44.905  1.00 66.57  ? 260 LEU E CG   1 
ATOM   6491  C  CD1  . LEU E 1 53  ? 59.839  -54.374 44.151  1.00 61.42  ? 260 LEU E CD1  1 
ATOM   6492  C  CD2  . LEU E 1 53  ? 59.769  -56.381 45.625  1.00 62.54  ? 260 LEU E CD2  1 
ATOM   6493  N  N    . GLN E 1 54  ? 54.920  -54.472 46.654  1.00 63.52  ? 261 GLN E N    1 
ATOM   6494  C  CA   . GLN E 1 54  ? 53.651  -55.168 46.953  1.00 66.09  ? 261 GLN E CA   1 
ATOM   6495  C  C    . GLN E 1 54  ? 52.585  -54.766 45.929  1.00 69.53  ? 261 GLN E C    1 
ATOM   6496  O  O    . GLN E 1 54  ? 51.872  -55.655 45.459  1.00 65.71  ? 261 GLN E O    1 
ATOM   6497  C  CB   . GLN E 1 54  ? 53.242  -54.836 48.385  1.00 64.97  ? 261 GLN E CB   1 
ATOM   6498  N  N    . ARG E 1 55  ? 52.508  -53.481 45.585  1.00 69.24  ? 262 ARG E N    1 
ATOM   6499  C  CA   . ARG E 1 55  ? 51.471  -52.994 44.641  1.00 65.71  ? 262 ARG E CA   1 
ATOM   6500  C  C    . ARG E 1 55  ? 51.795  -53.494 43.240  1.00 66.77  ? 262 ARG E C    1 
ATOM   6501  O  O    . ARG E 1 55  ? 50.893  -54.028 42.595  1.00 69.54  ? 262 ARG E O    1 
ATOM   6502  C  CB   . ARG E 1 55  ? 51.386  -51.467 44.652  1.00 63.68  ? 262 ARG E CB   1 
ATOM   6503  C  CG   . ARG E 1 55  ? 50.123  -50.908 44.017  1.00 62.34  ? 262 ARG E CG   1 
ATOM   6504  C  CD   . ARG E 1 55  ? 50.320  -49.478 43.561  1.00 62.19  ? 262 ARG E CD   1 
ATOM   6505  N  NE   . ARG E 1 55  ? 49.917  -48.524 44.582  1.00 67.97  ? 262 ARG E NE   1 
ATOM   6506  N  N    . VAL E 1 56  ? 53.038  -53.321 42.801  1.00 67.29  ? 263 VAL E N    1 
ATOM   6507  C  CA   . VAL E 1 56  ? 53.424  -53.739 41.425  1.00 60.34  ? 263 VAL E CA   1 
ATOM   6508  C  C    . VAL E 1 56  ? 53.072  -55.218 41.274  1.00 65.91  ? 263 VAL E C    1 
ATOM   6509  O  O    . VAL E 1 56  ? 52.389  -55.553 40.306  1.00 66.81  ? 263 VAL E O    1 
ATOM   6510  C  CB   . VAL E 1 56  ? 54.908  -53.447 41.140  1.00 58.99  ? 263 VAL E CB   1 
ATOM   6511  C  CG1  . VAL E 1 56  ? 55.354  -54.004 39.800  1.00 57.84  ? 263 VAL E CG1  1 
ATOM   6512  C  CG2  . VAL E 1 56  ? 55.213  -51.962 41.217  1.00 57.52  ? 263 VAL E CG2  1 
ATOM   6513  N  N    . PHE E 1 57  ? 53.460  -56.041 42.245  1.00 61.36  ? 264 PHE E N    1 
ATOM   6514  C  CA   . PHE E 1 57  ? 53.176  -57.494 42.192  1.00 65.37  ? 264 PHE E CA   1 
ATOM   6515  C  C    . PHE E 1 57  ? 51.660  -57.727 42.151  1.00 70.04  ? 264 PHE E C    1 
ATOM   6516  O  O    . PHE E 1 57  ? 51.196  -58.435 41.256  1.00 67.47  ? 264 PHE E O    1 
ATOM   6517  C  CB   . PHE E 1 57  ? 53.854  -58.208 43.365  1.00 59.85  ? 264 PHE E CB   1 
ATOM   6518  C  CG   . PHE E 1 57  ? 55.336  -58.443 43.219  1.00 59.67  ? 264 PHE E CG   1 
ATOM   6519  C  CD1  . PHE E 1 57  ? 56.021  -58.039 42.085  1.00 58.21  ? 264 PHE E CD1  1 
ATOM   6520  C  CD2  . PHE E 1 57  ? 56.048  -59.073 44.224  1.00 59.32  ? 264 PHE E CD2  1 
ATOM   6521  C  CE1  . PHE E 1 57  ? 57.383  -58.258 41.963  1.00 57.67  ? 264 PHE E CE1  1 
ATOM   6522  C  CE2  . PHE E 1 57  ? 57.408  -59.298 44.098  1.00 56.25  ? 264 PHE E CE2  1 
ATOM   6523  C  CZ   . PHE E 1 57  ? 58.073  -58.890 42.968  1.00 58.42  ? 264 PHE E CZ   1 
ATOM   6524  N  N    . TYR E 1 58  ? 50.915  -57.145 43.089  1.00 66.83  ? 265 TYR E N    1 
ATOM   6525  C  CA   . TYR E 1 58  ? 49.443  -57.330 43.144  1.00 73.09  ? 265 TYR E CA   1 
ATOM   6526  C  C    . TYR E 1 58  ? 48.835  -57.040 41.776  1.00 70.66  ? 265 TYR E C    1 
ATOM   6527  O  O    . TYR E 1 58  ? 48.080  -57.871 41.272  1.00 68.82  ? 265 TYR E O    1 
ATOM   6528  C  CB   . TYR E 1 58  ? 48.826  -56.407 44.196  1.00 66.58  ? 265 TYR E CB   1 
ATOM   6529  C  CG   . TYR E 1 58  ? 47.336  -56.519 44.394  1.00 73.93  ? 265 TYR E CG   1 
ATOM   6530  C  CD1  . TYR E 1 58  ? 46.808  -57.408 45.313  1.00 79.94  ? 265 TYR E CD1  1 
ATOM   6531  C  CD2  . TYR E 1 58  ? 46.453  -55.712 43.695  1.00 78.74  ? 265 TYR E CD2  1 
ATOM   6532  C  CE1  . TYR E 1 58  ? 45.443  -57.513 45.516  1.00 77.59  ? 265 TYR E CE1  1 
ATOM   6533  C  CE2  . TYR E 1 58  ? 45.085  -55.809 43.879  1.00 70.50  ? 265 TYR E CE2  1 
ATOM   6534  C  CZ   . TYR E 1 58  ? 44.578  -56.712 44.795  1.00 78.20  ? 265 TYR E CZ   1 
ATOM   6535  O  OH   . TYR E 1 58  ? 43.233  -56.812 44.988  1.00 85.65  ? 265 TYR E OH   1 
ATOM   6536  N  N    . GLU E 1 59  ? 49.175  -55.898 41.195  1.00 69.28  ? 266 GLU E N    1 
ATOM   6537  C  CA   . GLU E 1 59  ? 48.531  -55.492 39.926  1.00 70.86  ? 266 GLU E CA   1 
ATOM   6538  C  C    . GLU E 1 59  ? 49.053  -56.334 38.758  1.00 70.40  ? 266 GLU E C    1 
ATOM   6539  O  O    . GLU E 1 59  ? 48.312  -56.497 37.792  1.00 69.63  ? 266 GLU E O    1 
ATOM   6540  C  CB   . GLU E 1 59  ? 48.712  -53.986 39.770  1.00 72.19  ? 266 GLU E CB   1 
ATOM   6541  C  CG   . GLU E 1 59  ? 48.133  -53.207 40.933  1.00 75.25  ? 266 GLU E CG   1 
ATOM   6542  C  CD   . GLU E 1 59  ? 47.514  -51.875 40.562  1.00 82.19  ? 266 GLU E CD   1 
ATOM   6543  O  OE1  . GLU E 1 59  ? 48.203  -50.849 40.705  1.00 75.18  ? 266 GLU E OE1  1 
ATOM   6544  O  OE2  . GLU E 1 59  ? 46.344  -51.869 40.138  1.00 83.94  ? 266 GLU E OE2  1 
ATOM   6545  N  N    . LEU E 1 60  ? 50.256  -56.891 38.866  1.00 68.32  ? 267 LEU E N    1 
ATOM   6546  C  CA   . LEU E 1 60  ? 50.773  -57.791 37.806  1.00 66.66  ? 267 LEU E CA   1 
ATOM   6547  C  C    . LEU E 1 60  ? 49.976  -59.102 37.811  1.00 68.18  ? 267 LEU E C    1 
ATOM   6548  O  O    . LEU E 1 60  ? 50.067  -59.841 36.823  1.00 66.43  ? 267 LEU E O    1 
ATOM   6549  C  CB   . LEU E 1 60  ? 52.263  -58.043 38.049  1.00 65.52  ? 267 LEU E CB   1 
ATOM   6550  C  CG   . LEU E 1 60  ? 53.234  -57.037 37.441  1.00 65.37  ? 267 LEU E CG   1 
ATOM   6551  C  CD1  . LEU E 1 60  ? 54.660  -57.367 37.844  1.00 65.87  ? 267 LEU E CD1  1 
ATOM   6552  C  CD2  . LEU E 1 60  ? 53.107  -57.010 35.931  1.00 62.38  ? 267 LEU E CD2  1 
ATOM   6553  N  N    . GLN E 1 61  ? 49.230  -59.375 38.883  1.00 70.42  ? 268 GLN E N    1 
ATOM   6554  C  CA   . GLN E 1 61  ? 48.435  -60.622 38.994  1.00 66.14  ? 268 GLN E CA   1 
ATOM   6555  C  C    . GLN E 1 61  ? 46.938  -60.326 38.875  1.00 74.51  ? 268 GLN E C    1 
ATOM   6556  O  O    . GLN E 1 61  ? 46.179  -61.288 38.694  1.00 69.43  ? 268 GLN E O    1 
ATOM   6557  N  N    . HIS E 1 62  ? 46.536  -59.056 38.960  1.00 73.51  ? 269 HIS E N    1 
ATOM   6558  C  CA   . HIS E 1 62  ? 45.089  -58.708 38.941  1.00 75.49  ? 269 HIS E CA   1 
ATOM   6559  C  C    . HIS E 1 62  ? 44.745  -57.823 37.746  1.00 76.84  ? 269 HIS E C    1 
ATOM   6560  O  O    . HIS E 1 62  ? 43.849  -58.211 36.989  1.00 77.41  ? 269 HIS E O    1 
ATOM   6561  C  CB   . HIS E 1 62  ? 44.687  -58.080 40.272  1.00 73.09  ? 269 HIS E CB   1 
ATOM   6562  C  CG   . HIS E 1 62  ? 44.634  -59.101 41.349  1.00 80.26  ? 269 HIS E CG   1 
ATOM   6563  N  ND1  . HIS E 1 62  ? 45.474  -59.071 42.434  1.00 78.88  ? 269 HIS E ND1  1 
ATOM   6564  C  CD2  . HIS E 1 62  ? 43.885  -60.215 41.472  1.00 77.15  ? 269 HIS E CD2  1 
ATOM   6565  C  CE1  . HIS E 1 62  ? 45.225  -60.108 43.200  1.00 76.25  ? 269 HIS E CE1  1 
ATOM   6566  N  NE2  . HIS E 1 62  ? 44.256  -60.823 42.632  1.00 81.45  ? 269 HIS E NE2  1 
ATOM   6567  N  N    . SER E 1 63  ? 45.436  -56.697 37.584  1.00 80.78  ? 270 SER E N    1 
ATOM   6568  C  CA   . SER E 1 63  ? 45.114  -55.749 36.485  1.00 81.20  ? 270 SER E CA   1 
ATOM   6569  C  C    . SER E 1 63  ? 45.208  -56.436 35.123  1.00 83.36  ? 270 SER E C    1 
ATOM   6570  O  O    . SER E 1 63  ? 46.105  -57.272 34.935  1.00 78.52  ? 270 SER E O    1 
ATOM   6571  C  CB   . SER E 1 63  ? 45.977  -54.519 36.530  1.00 76.80  ? 270 SER E CB   1 
ATOM   6572  O  OG   . SER E 1 63  ? 45.554  -53.567 35.568  1.00 81.58  ? 270 SER E OG   1 
ATOM   6573  N  N    . ASP E 1 64  ? 44.294  -56.085 34.219  1.00 87.52  ? 271 ASP E N    1 
ATOM   6574  C  CA   . ASP E 1 64  ? 44.302  -56.633 32.842  1.00 80.69  ? 271 ASP E CA   1 
ATOM   6575  C  C    . ASP E 1 64  ? 45.000  -55.637 31.923  1.00 81.97  ? 271 ASP E C    1 
ATOM   6576  O  O    . ASP E 1 64  ? 45.275  -55.998 30.771  1.00 80.16  ? 271 ASP E O    1 
ATOM   6577  C  CB   . ASP E 1 64  ? 42.876  -56.868 32.359  1.00 83.44  ? 271 ASP E CB   1 
ATOM   6578  N  N    . LYS E 1 65  ? 45.270  -54.435 32.427  1.00 81.12  ? 272 LYS E N    1 
ATOM   6579  C  CA   . LYS E 1 65  ? 45.910  -53.377 31.613  1.00 79.96  ? 272 LYS E CA   1 
ATOM   6580  C  C    . LYS E 1 65  ? 47.325  -53.130 32.129  1.00 79.11  ? 272 LYS E C    1 
ATOM   6581  O  O    . LYS E 1 65  ? 47.531  -53.276 33.342  1.00 78.07  ? 272 LYS E O    1 
ATOM   6582  C  CB   . LYS E 1 65  ? 45.078  -52.096 31.703  1.00 78.90  ? 272 LYS E CB   1 
ATOM   6583  N  N    . PRO E 1 66  ? 48.319  -52.777 31.260  1.00 73.82  ? 273 PRO E N    1 
ATOM   6584  C  CA   . PRO E 1 66  ? 49.676  -52.444 31.694  1.00 72.52  ? 273 PRO E CA   1 
ATOM   6585  C  C    . PRO E 1 66  ? 49.790  -51.809 33.084  1.00 72.96  ? 273 PRO E C    1 
ATOM   6586  O  O    . PRO E 1 66  ? 49.136  -50.823 33.349  1.00 69.08  ? 273 PRO E O    1 
ATOM   6587  C  CB   . PRO E 1 66  ? 50.125  -51.475 30.597  1.00 73.29  ? 273 PRO E CB   1 
ATOM   6588  C  CG   . PRO E 1 66  ? 49.647  -52.135 29.348  1.00 64.60  ? 273 PRO E CG   1 
ATOM   6589  C  CD   . PRO E 1 66  ? 48.330  -52.748 29.762  1.00 65.08  ? 273 PRO E CD   1 
ATOM   6590  N  N    . VAL E 1 67  ? 50.659  -52.382 33.912  1.00 72.70  ? 274 VAL E N    1 
ATOM   6591  C  CA   . VAL E 1 67  ? 50.836  -51.914 35.320  1.00 69.17  ? 274 VAL E CA   1 
ATOM   6592  C  C    . VAL E 1 67  ? 51.923  -50.840 35.396  1.00 69.42  ? 274 VAL E C    1 
ATOM   6593  O  O    . VAL E 1 67  ? 52.880  -50.903 34.619  1.00 64.40  ? 274 VAL E O    1 
ATOM   6594  C  CB   . VAL E 1 67  ? 51.162  -53.118 36.221  1.00 71.48  ? 274 VAL E CB   1 
ATOM   6595  C  CG1  . VAL E 1 67  ? 51.367  -52.753 37.681  1.00 69.05  ? 274 VAL E CG1  1 
ATOM   6596  C  CG2  . VAL E 1 67  ? 50.123  -54.212 36.079  1.00 70.36  ? 274 VAL E CG2  1 
ATOM   6597  N  N    . GLY E 1 68  ? 51.770  -49.896 36.320  1.00 72.28  ? 275 GLY E N    1 
ATOM   6598  C  CA   . GLY E 1 68  ? 52.724  -48.784 36.452  1.00 65.98  ? 275 GLY E CA   1 
ATOM   6599  C  C    . GLY E 1 68  ? 53.789  -49.009 37.495  1.00 64.54  ? 275 GLY E C    1 
ATOM   6600  O  O    . GLY E 1 68  ? 53.608  -49.886 38.348  1.00 55.36  ? 275 GLY E O    1 
ATOM   6601  N  N    . THR E 1 69  ? 54.851  -48.208 37.440  1.00 66.42  ? 276 THR E N    1 
ATOM   6602  C  CA   . THR E 1 69  ? 56.002  -48.381 38.352  1.00 60.93  ? 276 THR E CA   1 
ATOM   6603  C  C    . THR E 1 69  ? 56.378  -47.041 38.971  1.00 60.19  ? 276 THR E C    1 
ATOM   6604  O  O    . THR E 1 69  ? 57.436  -46.981 39.599  1.00 62.58  ? 276 THR E O    1 
ATOM   6605  C  CB   . THR E 1 69  ? 57.195  -48.919 37.560  1.00 61.00  ? 276 THR E CB   1 
ATOM   6606  O  OG1  . THR E 1 69  ? 57.373  -48.134 36.381  1.00 51.67  ? 276 THR E OG1  1 
ATOM   6607  C  CG2  . THR E 1 69  ? 57.040  -50.373 37.174  1.00 59.04  ? 276 THR E CG2  1 
ATOM   6608  N  N    . LYS E 1 70  ? 55.539  -46.021 38.821  1.00 59.99  ? 277 LYS E N    1 
ATOM   6609  C  CA   . LYS E 1 70  ? 55.915  -44.655 39.273  1.00 60.39  ? 277 LYS E CA   1 
ATOM   6610  C  C    . LYS E 1 70  ? 56.213  -44.618 40.773  1.00 63.62  ? 277 LYS E C    1 
ATOM   6611  O  O    . LYS E 1 70  ? 57.170  -43.938 41.155  1.00 69.90  ? 277 LYS E O    1 
ATOM   6612  C  CB   . LYS E 1 70  ? 54.819  -43.661 38.893  1.00 62.69  ? 277 LYS E CB   1 
ATOM   6613  N  N    . LYS E 1 71  ? 55.429  -45.318 41.581  1.00 61.18  ? 278 LYS E N    1 
ATOM   6614  C  CA   . LYS E 1 71  ? 55.616  -45.278 43.050  1.00 57.77  ? 278 LYS E CA   1 
ATOM   6615  C  C    . LYS E 1 71  ? 56.913  -45.995 43.444  1.00 67.53  ? 278 LYS E C    1 
ATOM   6616  O  O    . LYS E 1 71  ? 57.496  -45.599 44.455  1.00 68.91  ? 278 LYS E O    1 
ATOM   6617  C  CB   . LYS E 1 71  ? 54.390  -45.883 43.736  1.00 61.77  ? 278 LYS E CB   1 
ATOM   6618  N  N    . LEU E 1 72  ? 57.344  -46.998 42.674  1.00 65.29  ? 279 LEU E N    1 
ATOM   6619  C  CA   . LEU E 1 72  ? 58.603  -47.733 42.958  1.00 65.22  ? 279 LEU E CA   1 
ATOM   6620  C  C    . LEU E 1 72  ? 59.795  -46.808 42.725  1.00 65.45  ? 279 LEU E C    1 
ATOM   6621  O  O    . LEU E 1 72  ? 60.690  -46.789 43.570  1.00 65.07  ? 279 LEU E O    1 
ATOM   6622  C  CB   . LEU E 1 72  ? 58.682  -48.966 42.057  1.00 63.90  ? 279 LEU E CB   1 
ATOM   6623  C  CG   . LEU E 1 72  ? 59.795  -49.959 42.371  1.00 62.95  ? 279 LEU E CG   1 
ATOM   6624  C  CD1  . LEU E 1 72  ? 59.678  -50.479 43.791  1.00 61.83  ? 279 LEU E CD1  1 
ATOM   6625  C  CD2  . LEU E 1 72  ? 59.767  -51.113 41.389  1.00 63.71  ? 279 LEU E CD2  1 
ATOM   6626  N  N    . THR E 1 73  ? 59.787  -46.067 41.620  1.00 61.83  ? 280 THR E N    1 
ATOM   6627  C  CA   . THR E 1 73  ? 60.887  -45.116 41.329  1.00 63.24  ? 280 THR E CA   1 
ATOM   6628  C  C    . THR E 1 73  ? 60.880  -43.998 42.370  1.00 63.32  ? 280 THR E C    1 
ATOM   6629  O  O    . THR E 1 73  ? 61.962  -43.567 42.771  1.00 67.55  ? 280 THR E O    1 
ATOM   6630  C  CB   . THR E 1 73  ? 60.808  -44.568 39.901  1.00 64.51  ? 280 THR E CB   1 
ATOM   6631  O  OG1  . THR E 1 73  ? 59.466  -44.193 39.591  1.00 59.42  ? 280 THR E OG1  1 
ATOM   6632  C  CG2  . THR E 1 73  ? 61.316  -45.562 38.883  1.00 61.84  ? 280 THR E CG2  1 
ATOM   6633  N  N    . LYS E 1 74  ? 59.700  -43.582 42.817  1.00 60.27  ? 281 LYS E N    1 
ATOM   6634  C  CA   . LYS E 1 74  ? 59.617  -42.534 43.859  1.00 64.41  ? 281 LYS E CA   1 
ATOM   6635  C  C    . LYS E 1 74  ? 60.190  -43.087 45.163  1.00 69.22  ? 281 LYS E C    1 
ATOM   6636  O  O    . LYS E 1 74  ? 60.880  -42.334 45.862  1.00 64.43  ? 281 LYS E O    1 
ATOM   6637  C  CB   . LYS E 1 74  ? 58.171  -42.069 44.018  1.00 58.38  ? 281 LYS E CB   1 
ATOM   6638  N  N    . SER E 1 75  ? 59.924  -44.359 45.456  1.00 66.11  ? 282 SER E N    1 
ATOM   6639  C  CA   . SER E 1 75  ? 60.435  -45.000 46.693  1.00 67.65  ? 282 SER E CA   1 
ATOM   6640  C  C    . SER E 1 75  ? 61.961  -45.112 46.649  1.00 64.71  ? 282 SER E C    1 
ATOM   6641  O  O    . SER E 1 75  ? 62.562  -45.226 47.721  1.00 60.16  ? 282 SER E O    1 
ATOM   6642  C  CB   . SER E 1 75  ? 59.772  -46.333 46.908  1.00 70.12  ? 282 SER E CB   1 
ATOM   6643  O  OG   . SER E 1 75  ? 60.411  -47.365 46.178  1.00 70.26  ? 282 SER E OG   1 
ATOM   6644  N  N    . PHE E 1 76  ? 62.550  -45.074 45.457  1.00 61.83  ? 283 PHE E N    1 
ATOM   6645  C  CA   . PHE E 1 76  ? 64.024  -45.122 45.314  1.00 64.76  ? 283 PHE E CA   1 
ATOM   6646  C  C    . PHE E 1 76  ? 64.622  -43.752 45.634  1.00 62.57  ? 283 PHE E C    1 
ATOM   6647  O  O    . PHE E 1 76  ? 65.853  -43.649 45.672  1.00 60.73  ? 283 PHE E O    1 
ATOM   6648  C  CB   . PHE E 1 76  ? 64.408  -45.514 43.888  1.00 64.24  ? 283 PHE E CB   1 
ATOM   6649  C  CG   . PHE E 1 76  ? 64.056  -46.909 43.449  1.00 64.66  ? 283 PHE E CG   1 
ATOM   6650  C  CD1  . PHE E 1 76  ? 63.767  -47.901 44.369  1.00 55.86  ? 283 PHE E CD1  1 
ATOM   6651  C  CD2  . PHE E 1 76  ? 64.034  -47.227 42.103  1.00 62.08  ? 283 PHE E CD2  1 
ATOM   6652  C  CE1  . PHE E 1 76  ? 63.449  -49.181 43.948  1.00 64.63  ? 283 PHE E CE1  1 
ATOM   6653  C  CE2  . PHE E 1 76  ? 63.719  -48.507 41.684  1.00 62.90  ? 283 PHE E CE2  1 
ATOM   6654  C  CZ   . PHE E 1 76  ? 63.430  -49.482 42.608  1.00 69.54  ? 283 PHE E CZ   1 
ATOM   6655  N  N    . GLY E 1 77  ? 63.780  -42.741 45.850  1.00 60.62  ? 284 GLY E N    1 
ATOM   6656  C  CA   . GLY E 1 77  ? 64.255  -41.372 46.115  1.00 58.40  ? 284 GLY E CA   1 
ATOM   6657  C  C    . GLY E 1 77  ? 64.563  -40.682 44.815  1.00 63.26  ? 284 GLY E C    1 
ATOM   6658  O  O    . GLY E 1 77  ? 65.396  -39.771 44.818  1.00 63.05  ? 284 GLY E O    1 
ATOM   6659  N  N    . TRP E 1 78  ? 63.877  -41.081 43.750  1.00 62.18  ? 285 TRP E N    1 
ATOM   6660  C  CA   . TRP E 1 78  ? 64.232  -40.551 42.416  1.00 65.06  ? 285 TRP E CA   1 
ATOM   6661  C  C    . TRP E 1 78  ? 63.372  -39.353 42.033  1.00 66.26  ? 285 TRP E C    1 
ATOM   6662  O  O    . TRP E 1 78  ? 62.249  -39.230 42.542  1.00 63.76  ? 285 TRP E O    1 
ATOM   6663  C  CB   . TRP E 1 78  ? 64.140  -41.661 41.373  1.00 59.33  ? 285 TRP E CB   1 
ATOM   6664  C  CG   . TRP E 1 78  ? 65.287  -42.618 41.396  1.00 66.05  ? 285 TRP E CG   1 
ATOM   6665  C  CD1  . TRP E 1 78  ? 66.348  -42.626 42.253  1.00 65.58  ? 285 TRP E CD1  1 
ATOM   6666  C  CD2  . TRP E 1 78  ? 65.491  -43.720 40.499  1.00 65.25  ? 285 TRP E CD2  1 
ATOM   6667  N  NE1  . TRP E 1 78  ? 67.194  -43.658 41.954  1.00 62.83  ? 285 TRP E NE1  1 
ATOM   6668  C  CE2  . TRP E 1 78  ? 66.695  -44.345 40.881  1.00 70.51  ? 285 TRP E CE2  1 
ATOM   6669  C  CE3  . TRP E 1 78  ? 64.777  -44.233 39.413  1.00 61.71  ? 285 TRP E CE3  1 
ATOM   6670  C  CZ2  . TRP E 1 78  ? 67.196  -45.459 40.213  1.00 69.46  ? 285 TRP E CZ2  1 
ATOM   6671  C  CZ3  . TRP E 1 78  ? 65.271  -45.335 38.756  1.00 57.67  ? 285 TRP E CZ3  1 
ATOM   6672  C  CH2  . TRP E 1 78  ? 66.463  -45.937 39.152  1.00 58.91  ? 285 TRP E CH2  1 
ATOM   6673  N  N    . GLU E 1 79  ? 63.921  -38.500 41.175  1.00 62.82  ? 286 GLU E N    1 
ATOM   6674  C  CA   . GLU E 1 79  ? 63.157  -37.347 40.655  1.00 60.89  ? 286 GLU E CA   1 
ATOM   6675  C  C    . GLU E 1 79  ? 62.679  -37.698 39.249  1.00 62.65  ? 286 GLU E C    1 
ATOM   6676  O  O    . GLU E 1 79  ? 62.967  -38.812 38.783  1.00 61.69  ? 286 GLU E O    1 
ATOM   6677  C  CB   . GLU E 1 79  ? 64.027  -36.093 40.658  1.00 60.22  ? 286 GLU E CB   1 
ATOM   6678  C  CG   . GLU E 1 79  ? 64.493  -35.672 42.039  1.00 61.64  ? 286 GLU E CG   1 
ATOM   6679  C  CD   . GLU E 1 79  ? 63.461  -35.008 42.938  1.00 74.38  ? 286 GLU E CD   1 
ATOM   6680  O  OE1  . GLU E 1 79  ? 62.386  -34.622 42.437  1.00 73.28  ? 286 GLU E OE1  1 
ATOM   6681  O  OE2  . GLU E 1 79  ? 63.741  -34.870 44.144  1.00 70.10  ? 286 GLU E OE2  1 
ATOM   6682  N  N    . THR E 1 80  ? 61.985  -36.776 38.594  1.00 59.32  ? 287 THR E N    1 
ATOM   6683  C  CA   . THR E 1 80  ? 61.401  -37.054 37.256  1.00 54.36  ? 287 THR E CA   1 
ATOM   6684  C  C    . THR E 1 80  ? 62.488  -37.451 36.256  1.00 56.89  ? 287 THR E C    1 
ATOM   6685  O  O    . THR E 1 80  ? 62.263  -38.409 35.515  1.00 57.22  ? 287 THR E O    1 
ATOM   6686  C  CB   . THR E 1 80  ? 60.578  -35.840 36.805  1.00 59.44  ? 287 THR E CB   1 
ATOM   6687  O  OG1  . THR E 1 80  ? 61.430  -34.794 36.342  1.00 50.40  ? 287 THR E OG1  1 
ATOM   6688  C  CG2  . THR E 1 80  ? 59.692  -35.294 37.904  1.00 54.23  ? 287 THR E CG2  1 
ATOM   6689  N  N    . LEU E 1 81  ? 63.621  -36.759 36.259  1.00 58.26  ? 288 LEU E N    1 
ATOM   6690  C  CA   . LEU E 1 81  ? 64.715  -36.988 35.284  1.00 56.46  ? 288 LEU E CA   1 
ATOM   6691  C  C    . LEU E 1 81  ? 65.279  -38.403 35.382  1.00 62.80  ? 288 LEU E C    1 
ATOM   6692  O  O    . LEU E 1 81  ? 65.676  -38.934 34.336  1.00 55.00  ? 288 LEU E O    1 
ATOM   6693  C  CB   . LEU E 1 81  ? 65.789  -35.966 35.644  1.00 54.77  ? 288 LEU E CB   1 
ATOM   6694  C  CG   . LEU E 1 81  ? 66.959  -35.803 34.688  1.00 53.92  ? 288 LEU E CG   1 
ATOM   6695  C  CD1  . LEU E 1 81  ? 66.536  -34.990 33.479  1.00 63.85  ? 288 LEU E CD1  1 
ATOM   6696  C  CD2  . LEU E 1 81  ? 68.092  -35.113 35.420  1.00 53.61  ? 288 LEU E CD2  1 
ATOM   6697  N  N    . ASP E 1 82  ? 65.301  -38.993 36.577  1.00 55.68  ? 289 ASP E N    1 
ATOM   6698  C  CA   . ASP E 1 82  ? 65.946  -40.317 36.772  1.00 54.78  ? 289 ASP E CA   1 
ATOM   6699  C  C    . ASP E 1 82  ? 65.192  -41.405 36.004  1.00 59.54  ? 289 ASP E C    1 
ATOM   6700  O  O    . ASP E 1 82  ? 65.813  -42.422 35.670  1.00 55.45  ? 289 ASP E O    1 
ATOM   6701  C  CB   . ASP E 1 82  ? 66.112  -40.617 38.261  1.00 56.90  ? 289 ASP E CB   1 
ATOM   6702  C  CG   . ASP E 1 82  ? 66.966  -39.600 38.987  1.00 61.87  ? 289 ASP E CG   1 
ATOM   6703  O  OD1  . ASP E 1 82  ? 68.107  -39.381 38.551  1.00 61.56  ? 289 ASP E OD1  1 
ATOM   6704  O  OD2  . ASP E 1 82  ? 66.480  -39.039 39.980  1.00 63.39  ? 289 ASP E OD2  1 
ATOM   6705  N  N    . SER E 1 83  ? 63.926  -41.169 35.679  1.00 57.05  ? 290 SER E N    1 
ATOM   6706  C  CA   . SER E 1 83  ? 63.114  -42.157 34.932  1.00 61.38  ? 290 SER E CA   1 
ATOM   6707  C  C    . SER E 1 83  ? 63.550  -42.237 33.464  1.00 58.93  ? 290 SER E C    1 
ATOM   6708  O  O    . SER E 1 83  ? 62.924  -43.001 32.724  1.00 60.43  ? 290 SER E O    1 
ATOM   6709  C  CB   . SER E 1 83  ? 61.665  -41.822 35.068  1.00 56.84  ? 290 SER E CB   1 
ATOM   6710  O  OG   . SER E 1 83  ? 61.252  -41.927 36.421  1.00 65.42  ? 290 SER E OG   1 
ATOM   6711  N  N    . PHE E 1 84  ? 64.593  -41.506 33.071  1.00 56.81  ? 291 PHE E N    1 
ATOM   6712  C  CA   . PHE E 1 84  ? 65.048  -41.468 31.660  1.00 52.63  ? 291 PHE E CA   1 
ATOM   6713  C  C    . PHE E 1 84  ? 66.508  -41.904 31.559  1.00 54.41  ? 291 PHE E C    1 
ATOM   6714  O  O    . PHE E 1 84  ? 67.104  -41.708 30.494  1.00 59.75  ? 291 PHE E O    1 
ATOM   6715  C  CB   . PHE E 1 84  ? 64.818  -40.079 31.072  1.00 55.91  ? 291 PHE E CB   1 
ATOM   6716  C  CG   . PHE E 1 84  ? 63.374  -39.694 30.899  1.00 54.54  ? 291 PHE E CG   1 
ATOM   6717  C  CD1  . PHE E 1 84  ? 62.676  -40.062 29.763  1.00 50.30  ? 291 PHE E CD1  1 
ATOM   6718  C  CD2  . PHE E 1 84  ? 62.716  -38.955 31.869  1.00 52.32  ? 291 PHE E CD2  1 
ATOM   6719  C  CE1  . PHE E 1 84  ? 61.349  -39.704 29.602  1.00 55.25  ? 291 PHE E CE1  1 
ATOM   6720  C  CE2  . PHE E 1 84  ? 61.388  -38.601 31.708  1.00 53.41  ? 291 PHE E CE2  1 
ATOM   6721  C  CZ   . PHE E 1 84  ? 60.708  -38.975 30.575  1.00 51.52  ? 291 PHE E CZ   1 
ATOM   6722  N  N    . MET E 1 85  ? 67.063  -42.476 32.626  1.00 59.81  ? 292 MET E N    1 
ATOM   6723  C  CA   . MET E 1 85  ? 68.407  -43.028 32.569  1.00 57.60  ? 292 MET E CA   1 
ATOM   6724  C  C    . MET E 1 85  ? 68.340  -44.544 32.448  1.00 59.89  ? 292 MET E C    1 
ATOM   6725  O  O    . MET E 1 85  ? 67.706  -45.213 33.276  1.00 60.80  ? 292 MET E O    1 
ATOM   6726  C  CB   . MET E 1 85  ? 69.229  -42.649 33.799  1.00 62.02  ? 292 MET E CB   1 
ATOM   6727  C  CG   . MET E 1 85  ? 70.639  -43.261 33.768  1.00 63.47  ? 292 MET E CG   1 
ATOM   6728  S  SD   . MET E 1 85  ? 71.924  -42.202 34.455  1.00 81.34  ? 292 MET E SD   1 
ATOM   6729  C  CE   . MET E 1 85  ? 71.810  -42.592 36.211  1.00 72.97  ? 292 MET E CE   1 
ATOM   6730  N  N    . GLN E 1 86  ? 69.001  -45.067 31.415  1.00 54.99  ? 293 GLN E N    1 
ATOM   6731  C  CA   . GLN E 1 86  ? 69.133  -46.498 31.184  1.00 58.43  ? 293 GLN E CA   1 
ATOM   6732  C  C    . GLN E 1 86  ? 70.051  -47.136 32.225  1.00 60.80  ? 293 GLN E C    1 
ATOM   6733  O  O    . GLN E 1 86  ? 70.954  -46.485 32.766  1.00 58.04  ? 293 GLN E O    1 
ATOM   6734  C  CB   . GLN E 1 86  ? 69.686  -46.737 29.779  1.00 57.16  ? 293 GLN E CB   1 
ATOM   6735  C  CG   . GLN E 1 86  ? 68.794  -46.159 28.663  1.00 55.68  ? 293 GLN E CG   1 
ATOM   6736  C  CD   . GLN E 1 86  ? 69.200  -46.636 27.281  1.00 60.96  ? 293 GLN E CD   1 
ATOM   6737  O  OE1  . GLN E 1 86  ? 70.039  -47.530 27.132  1.00 64.89  ? 293 GLN E OE1  1 
ATOM   6738  N  NE2  . GLN E 1 86  ? 68.616  -46.032 26.261  1.00 63.09  ? 293 GLN E NE2  1 
ATOM   6739  N  N    . HIS E 1 87  ? 69.826  -48.425 32.501  1.00 56.04  ? 294 HIS E N    1 
ATOM   6740  C  CA   . HIS E 1 87  ? 70.564  -49.064 33.580  1.00 52.59  ? 294 HIS E CA   1 
ATOM   6741  C  C    . HIS E 1 87  ? 70.834  -50.541 33.302  1.00 56.38  ? 294 HIS E C    1 
ATOM   6742  O  O    . HIS E 1 87  ? 70.231  -51.158 32.425  1.00 58.99  ? 294 HIS E O    1 
ATOM   6743  C  CB   . HIS E 1 87  ? 69.831  -48.889 34.911  1.00 53.26  ? 294 HIS E CB   1 
ATOM   6744  C  CG   . HIS E 1 87  ? 70.035  -47.540 35.525  1.00 53.78  ? 294 HIS E CG   1 
ATOM   6745  N  ND1  . HIS E 1 87  ? 69.043  -46.584 35.570  1.00 58.35  ? 294 HIS E ND1  1 
ATOM   6746  C  CD2  . HIS E 1 87  ? 71.129  -46.973 36.083  1.00 52.46  ? 294 HIS E CD2  1 
ATOM   6747  C  CE1  . HIS E 1 87  ? 69.513  -45.492 36.147  1.00 58.52  ? 294 HIS E CE1  1 
ATOM   6748  N  NE2  . HIS E 1 87  ? 70.775  -45.704 36.473  1.00 53.31  ? 294 HIS E NE2  1 
ATOM   6749  N  N    . ASP E 1 88  ? 71.786  -51.087 34.068  1.00 60.68  ? 295 ASP E N    1 
ATOM   6750  C  CA   . ASP E 1 88  ? 72.127  -52.506 34.042  1.00 56.14  ? 295 ASP E CA   1 
ATOM   6751  C  C    . ASP E 1 88  ? 71.165  -53.276 34.958  1.00 56.46  ? 295 ASP E C    1 
ATOM   6752  O  O    . ASP E 1 88  ? 70.956  -52.899 36.120  1.00 53.08  ? 295 ASP E O    1 
ATOM   6753  C  CB   . ASP E 1 88  ? 73.596  -52.681 34.469  1.00 51.88  ? 295 ASP E CB   1 
ATOM   6754  C  CG   . ASP E 1 88  ? 74.038  -54.153 34.554  1.00 56.51  ? 295 ASP E CG   1 
ATOM   6755  O  OD1  . ASP E 1 88  ? 73.624  -54.860 35.500  1.00 58.90  ? 295 ASP E OD1  1 
ATOM   6756  O  OD2  . ASP E 1 88  ? 74.828  -54.601 33.699  1.00 52.86  ? 295 ASP E OD2  1 
ATOM   6757  N  N    . VAL E 1 89  ? 70.571  -54.351 34.428  1.00 56.49  ? 296 VAL E N    1 
ATOM   6758  C  CA   . VAL E 1 89  ? 69.529  -55.072 35.165  1.00 52.69  ? 296 VAL E CA   1 
ATOM   6759  C  C    . VAL E 1 89  ? 70.117  -55.832 36.360  1.00 48.21  ? 296 VAL E C    1 
ATOM   6760  O  O    . VAL E 1 89  ? 69.490  -55.914 37.422  1.00 47.95  ? 296 VAL E O    1 
ATOM   6761  C  CB   . VAL E 1 89  ? 68.746  -55.999 34.207  1.00 49.29  ? 296 VAL E CB   1 
ATOM   6762  C  CG1  . VAL E 1 89  ? 69.609  -57.141 33.698  1.00 47.89  ? 296 VAL E CG1  1 
ATOM   6763  C  CG2  . VAL E 1 89  ? 67.485  -56.544 34.885  1.00 49.58  ? 296 VAL E CG2  1 
ATOM   6764  N  N    . GLN E 1 90  ? 71.325  -56.380 36.245  1.00 51.17  ? 297 GLN E N    1 
ATOM   6765  C  CA   . GLN E 1 90  ? 71.942  -57.085 37.398  1.00 51.53  ? 297 GLN E CA   1 
ATOM   6766  C  C    . GLN E 1 90  ? 72.261  -56.077 38.497  1.00 52.77  ? 297 GLN E C    1 
ATOM   6767  O  O    . GLN E 1 90  ? 72.131  -56.430 39.668  1.00 52.18  ? 297 GLN E O    1 
ATOM   6768  C  CB   . GLN E 1 90  ? 73.179  -57.876 36.984  1.00 52.26  ? 297 GLN E CB   1 
ATOM   6769  C  CG   . GLN E 1 90  ? 73.683  -58.815 38.068  1.00 54.44  ? 297 GLN E CG   1 
ATOM   6770  C  CD   . GLN E 1 90  ? 74.959  -58.293 38.677  1.00 53.74  ? 297 GLN E CD   1 
ATOM   6771  O  OE1  . GLN E 1 90  ? 75.630  -57.445 38.113  1.00 49.58  ? 297 GLN E OE1  1 
ATOM   6772  N  NE2  . GLN E 1 90  ? 75.341  -58.832 39.815  1.00 54.89  ? 297 GLN E NE2  1 
ATOM   6773  N  N    . GLU E 1 91  ? 72.676  -54.874 38.124  1.00 54.67  ? 298 GLU E N    1 
ATOM   6774  C  CA   . GLU E 1 91  ? 72.858  -53.838 39.137  1.00 55.49  ? 298 GLU E CA   1 
ATOM   6775  C  C    . GLU E 1 91  ? 71.578  -53.616 39.931  1.00 54.56  ? 298 GLU E C    1 
ATOM   6776  O  O    . GLU E 1 91  ? 71.588  -53.650 41.174  1.00 53.93  ? 298 GLU E O    1 
ATOM   6777  C  CB   . GLU E 1 91  ? 73.315  -52.526 38.491  1.00 54.23  ? 298 GLU E CB   1 
ATOM   6778  C  CG   . GLU E 1 91  ? 73.906  -51.569 39.499  1.00 51.03  ? 298 GLU E CG   1 
ATOM   6779  C  CD   . GLU E 1 91  ? 74.604  -50.348 38.897  1.00 57.57  ? 298 GLU E CD   1 
ATOM   6780  O  OE1  . GLU E 1 91  ? 75.099  -49.549 39.715  1.00 61.67  ? 298 GLU E OE1  1 
ATOM   6781  O  OE2  . GLU E 1 91  ? 74.667  -50.168 37.646  1.00 52.84  ? 298 GLU E OE2  1 
ATOM   6782  N  N    . LEU E 1 92  ? 70.464  -53.374 39.232  1.00 49.43  ? 299 LEU E N    1 
ATOM   6783  C  CA   . LEU E 1 92  ? 69.191  -53.195 39.927  1.00 49.24  ? 299 LEU E CA   1 
ATOM   6784  C  C    . LEU E 1 92  ? 68.905  -54.350 40.888  1.00 53.02  ? 299 LEU E C    1 
ATOM   6785  O  O    . LEU E 1 92  ? 68.438  -54.127 42.008  1.00 52.20  ? 299 LEU E O    1 
ATOM   6786  C  CB   . LEU E 1 92  ? 68.063  -53.062 38.911  1.00 44.74  ? 299 LEU E CB   1 
ATOM   6787  C  CG   . LEU E 1 92  ? 66.671  -52.885 39.515  1.00 48.71  ? 299 LEU E CG   1 
ATOM   6788  C  CD1  . LEU E 1 92  ? 66.686  -51.760 40.543  1.00 47.50  ? 299 LEU E CD1  1 
ATOM   6789  C  CD2  . LEU E 1 92  ? 65.656  -52.611 38.419  1.00 50.30  ? 299 LEU E CD2  1 
ATOM   6790  N  N    . CYS E 1 93  ? 69.216  -55.590 40.471  1.00 50.82  ? 300 CYS E N    1 
ATOM   6791  C  CA   . CYS E 1 93  ? 68.869  -56.792 41.234  1.00 51.81  ? 300 CYS E CA   1 
ATOM   6792  C  C    . CYS E 1 93  ? 69.716  -56.945 42.496  1.00 54.60  ? 300 CYS E C    1 
ATOM   6793  O  O    . CYS E 1 93  ? 69.214  -57.373 43.548  1.00 51.19  ? 300 CYS E O    1 
ATOM   6794  C  CB   . CYS E 1 93  ? 69.031  -58.019 40.333  1.00 51.27  ? 300 CYS E CB   1 
ATOM   6795  S  SG   . CYS E 1 93  ? 68.742  -59.602 41.118  1.00 58.89  ? 300 CYS E SG   1 
ATOM   6796  N  N    . ARG E 1 94  ? 71.012  -56.651 42.404  1.00 50.95  ? 301 ARG E N    1 
ATOM   6797  C  CA   . ARG E 1 94  ? 71.833  -56.630 43.608  1.00 49.41  ? 301 ARG E CA   1 
ATOM   6798  C  C    . ARG E 1 94  ? 71.269  -55.638 44.619  1.00 53.39  ? 301 ARG E C    1 
ATOM   6799  O  O    . ARG E 1 94  ? 71.068  -55.969 45.793  1.00 51.53  ? 301 ARG E O    1 
ATOM   6800  C  CB   . ARG E 1 94  ? 73.296  -56.292 43.267  1.00 49.19  ? 301 ARG E CB   1 
ATOM   6801  C  CG   . ARG E 1 94  ? 74.057  -57.358 42.391  1.00 52.69  ? 301 ARG E CG   1 
ATOM   6802  C  CD   . ARG E 1 94  ? 74.577  -58.548 43.224  1.00 49.29  ? 301 ARG E CD   1 
ATOM   6803  N  NE   . ARG E 1 94  ? 73.482  -59.213 43.935  1.00 48.29  ? 301 ARG E NE   1 
ATOM   6804  C  CZ   . ARG E 1 94  ? 72.614  -60.047 43.367  1.00 52.09  ? 301 ARG E CZ   1 
ATOM   6805  N  NH1  . ARG E 1 94  ? 72.729  -60.379 42.078  1.00 50.32  ? 301 ARG E NH1  1 
ATOM   6806  N  NH2  . ARG E 1 94  ? 71.639  -60.572 44.097  1.00 49.56  ? 301 ARG E NH2  1 
ATOM   6807  N  N    . VAL E 1 95  ? 70.989  -54.412 44.176  1.00 50.58  ? 302 VAL E N    1 
ATOM   6808  C  CA   . VAL E 1 95  ? 70.523  -53.397 45.108  1.00 47.79  ? 302 VAL E CA   1 
ATOM   6809  C  C    . VAL E 1 95  ? 69.096  -53.691 45.541  1.00 53.00  ? 302 VAL E C    1 
ATOM   6810  O  O    . VAL E 1 95  ? 68.768  -53.615 46.731  1.00 54.77  ? 302 VAL E O    1 
ATOM   6811  C  CB   . VAL E 1 95  ? 70.636  -51.992 44.489  1.00 58.55  ? 302 VAL E CB   1 
ATOM   6812  C  CG1  . VAL E 1 95  ? 70.252  -50.950 45.504  1.00 46.97  ? 302 VAL E CG1  1 
ATOM   6813  C  CG2  . VAL E 1 95  ? 72.050  -51.741 43.921  1.00 53.30  ? 302 VAL E CG2  1 
ATOM   6814  N  N    . LEU E 1 96  ? 68.228  -54.046 44.592  1.00 52.65  ? 303 LEU E N    1 
ATOM   6815  C  CA   . LEU E 1 96  ? 66.822  -54.257 44.928  1.00 54.56  ? 303 LEU E CA   1 
ATOM   6816  C  C    . LEU E 1 96  ? 66.655  -55.410 45.911  1.00 55.40  ? 303 LEU E C    1 
ATOM   6817  O  O    . LEU E 1 96  ? 65.944  -55.274 46.913  1.00 57.20  ? 303 LEU E O    1 
ATOM   6818  C  CB   . LEU E 1 96  ? 66.001  -54.492 43.663  1.00 48.53  ? 303 LEU E CB   1 
ATOM   6819  C  CG   . LEU E 1 96  ? 64.481  -54.523 43.805  1.00 55.55  ? 303 LEU E CG   1 
ATOM   6820  C  CD1  . LEU E 1 96  ? 64.002  -55.919 44.062  1.00 58.45  ? 303 LEU E CD1  1 
ATOM   6821  C  CD2  . LEU E 1 96  ? 63.985  -53.595 44.921  1.00 56.41  ? 303 LEU E CD2  1 
ATOM   6822  N  N    . LEU E 1 97  ? 67.325  -56.532 45.664  1.00 49.38  ? 304 LEU E N    1 
ATOM   6823  C  CA   . LEU E 1 97  ? 67.131  -57.706 46.548  1.00 51.12  ? 304 LEU E CA   1 
ATOM   6824  C  C    . LEU E 1 97  ? 67.759  -57.424 47.911  1.00 53.12  ? 304 LEU E C    1 
ATOM   6825  O  O    . LEU E 1 97  ? 67.142  -57.791 48.903  1.00 53.85  ? 304 LEU E O    1 
ATOM   6826  C  CB   . LEU E 1 97  ? 67.726  -58.965 45.915  1.00 51.95  ? 304 LEU E CB   1 
ATOM   6827  C  CG   . LEU E 1 97  ? 66.898  -59.629 44.820  1.00 55.29  ? 304 LEU E CG   1 
ATOM   6828  C  CD1  . LEU E 1 97  ? 67.468  -60.995 44.481  1.00 50.35  ? 304 LEU E CD1  1 
ATOM   6829  C  CD2  . LEU E 1 97  ? 65.444  -59.750 45.231  1.00 55.33  ? 304 LEU E CD2  1 
ATOM   6830  N  N    . ASP E 1 98  ? 68.926  -56.784 47.957  1.00 51.87  ? 305 ASP E N    1 
ATOM   6831  C  CA   . ASP E 1 98  ? 69.518  -56.417 49.240  1.00 54.64  ? 305 ASP E CA   1 
ATOM   6832  C  C    . ASP E 1 98  ? 68.540  -55.584 50.061  1.00 55.41  ? 305 ASP E C    1 
ATOM   6833  O  O    . ASP E 1 98  ? 68.330  -55.835 51.252  1.00 52.67  ? 305 ASP E O    1 
ATOM   6834  C  CB   . ASP E 1 98  ? 70.817  -55.657 49.002  1.00 51.42  ? 305 ASP E CB   1 
ATOM   6835  C  CG   . ASP E 1 98  ? 71.542  -55.326 50.281  1.00 50.63  ? 305 ASP E CG   1 
ATOM   6836  O  OD1  . ASP E 1 98  ? 72.081  -56.247 50.919  1.00 57.10  ? 305 ASP E OD1  1 
ATOM   6837  O  OD2  . ASP E 1 98  ? 71.582  -54.137 50.642  1.00 51.99  ? 305 ASP E OD2  1 
ATOM   6838  N  N    . ASN E 1 99  ? 67.916  -54.602 49.415  1.00 50.26  ? 306 ASN E N    1 
ATOM   6839  C  CA   . ASN E 1 99  ? 66.899  -53.780 50.048  1.00 57.37  ? 306 ASN E CA   1 
ATOM   6840  C  C    . ASN E 1 99  ? 65.787  -54.634 50.658  1.00 56.17  ? 306 ASN E C    1 
ATOM   6841  O  O    . ASN E 1 99  ? 65.444  -54.485 51.837  1.00 53.43  ? 306 ASN E O    1 
ATOM   6842  C  CB   . ASN E 1 99  ? 66.341  -52.810 49.000  1.00 59.66  ? 306 ASN E CB   1 
ATOM   6843  C  CG   . ASN E 1 99  ? 65.252  -51.912 49.550  1.00 67.10  ? 306 ASN E CG   1 
ATOM   6844  O  OD1  . ASN E 1 99  ? 64.220  -52.385 50.056  1.00 64.23  ? 306 ASN E OD1  1 
ATOM   6845  N  ND2  . ASN E 1 99  ? 65.467  -50.604 49.445  1.00 64.86  ? 306 ASN E ND2  1 
ATOM   6846  N  N    . VAL E 1 100 ? 65.218  -55.541 49.867  1.00 51.47  ? 307 VAL E N    1 
ATOM   6847  C  CA   . VAL E 1 100 ? 64.074  -56.303 50.342  1.00 54.69  ? 307 VAL E CA   1 
ATOM   6848  C  C    . VAL E 1 100 ? 64.490  -57.313 51.405  1.00 56.64  ? 307 VAL E C    1 
ATOM   6849  O  O    . VAL E 1 100 ? 63.761  -57.526 52.383  1.00 60.87  ? 307 VAL E O    1 
ATOM   6850  C  CB   . VAL E 1 100 ? 63.352  -56.967 49.160  1.00 52.28  ? 307 VAL E CB   1 
ATOM   6851  C  CG1  . VAL E 1 100 ? 62.216  -57.869 49.667  1.00 50.98  ? 307 VAL E CG1  1 
ATOM   6852  C  CG2  . VAL E 1 100 ? 62.828  -55.897 48.245  1.00 38.07  ? 307 VAL E CG2  1 
ATOM   6853  N  N    . GLU E 1 101 ? 65.670  -57.929 51.254  1.00 56.28  ? 308 GLU E N    1 
ATOM   6854  C  CA   . GLU E 1 101 ? 66.141  -58.901 52.247  1.00 49.34  ? 308 GLU E CA   1 
ATOM   6855  C  C    . GLU E 1 101 ? 66.302  -58.259 53.617  1.00 53.39  ? 308 GLU E C    1 
ATOM   6856  O  O    . GLU E 1 101 ? 65.961  -58.858 54.641  1.00 55.59  ? 308 GLU E O    1 
ATOM   6857  C  CB   . GLU E 1 101 ? 67.464  -59.511 51.799  1.00 50.32  ? 308 GLU E CB   1 
ATOM   6858  C  CG   . GLU E 1 101 ? 68.213  -60.242 52.898  1.00 55.37  ? 308 GLU E CG   1 
ATOM   6859  C  CD   . GLU E 1 101 ? 69.568  -60.797 52.462  1.00 57.56  ? 308 GLU E CD   1 
ATOM   6860  O  OE1  . GLU E 1 101 ? 70.224  -61.440 53.308  1.00 65.50  ? 308 GLU E OE1  1 
ATOM   6861  O  OE2  . GLU E 1 101 ? 69.988  -60.602 51.293  1.00 64.72  ? 308 GLU E OE2  1 
ATOM   6862  N  N    . ASN E 1 102 ? 66.813  -57.033 53.654  1.00 59.65  ? 309 ASN E N    1 
ATOM   6863  C  CA   . ASN E 1 102 ? 66.984  -56.332 54.918  1.00 60.52  ? 309 ASN E CA   1 
ATOM   6864  C  C    . ASN E 1 102 ? 65.658  -55.826 55.470  1.00 63.67  ? 309 ASN E C    1 
ATOM   6865  O  O    . ASN E 1 102 ? 65.487  -55.754 56.690  1.00 64.85  ? 309 ASN E O    1 
ATOM   6866  C  CB   . ASN E 1 102 ? 67.945  -55.169 54.735  1.00 60.29  ? 309 ASN E CB   1 
ATOM   6867  C  CG   . ASN E 1 102 ? 68.819  -54.955 55.936  1.00 69.20  ? 309 ASN E CG   1 
ATOM   6868  O  OD1  . ASN E 1 102 ? 69.812  -55.671 56.138  1.00 63.44  ? 309 ASN E OD1  1 
ATOM   6869  N  ND2  . ASN E 1 102 ? 68.459  -53.966 56.756  1.00 73.29  ? 309 ASN E ND2  1 
ATOM   6870  N  N    . LYS E 1 103 ? 64.721  -55.448 54.599  1.00 60.37  ? 310 LYS E N    1 
ATOM   6871  C  CA   . LYS E 1 103 ? 63.384  -55.092 55.076  1.00 60.50  ? 310 LYS E CA   1 
ATOM   6872  C  C    . LYS E 1 103 ? 62.681  -56.288 55.717  1.00 62.37  ? 310 LYS E C    1 
ATOM   6873  O  O    . LYS E 1 103 ? 61.960  -56.122 56.705  1.00 64.07  ? 310 LYS E O    1 
ATOM   6874  N  N    . MET E 1 104 ? 62.903  -57.497 55.186  1.00 60.21  ? 311 MET E N    1 
ATOM   6875  C  CA   . MET E 1 104 ? 62.338  -58.729 55.724  1.00 60.11  ? 311 MET E CA   1 
ATOM   6876  C  C    . MET E 1 104 ? 62.956  -59.149 57.056  1.00 65.62  ? 311 MET E C    1 
ATOM   6877  O  O    . MET E 1 104 ? 62.396  -60.030 57.724  1.00 68.60  ? 311 MET E O    1 
ATOM   6878  C  CB   . MET E 1 104 ? 62.509  -59.874 54.709  1.00 56.31  ? 311 MET E CB   1 
ATOM   6879  C  CG   . MET E 1 104 ? 61.626  -59.804 53.481  1.00 58.31  ? 311 MET E CG   1 
ATOM   6880  S  SD   . MET E 1 104 ? 61.652  -61.333 52.517  1.00 69.97  ? 311 MET E SD   1 
ATOM   6881  C  CE   . MET E 1 104 ? 60.649  -60.852 51.111  1.00 62.17  ? 311 MET E CE   1 
ATOM   6882  N  N    . LYS E 1 105 ? 64.102  -58.586 57.438  1.00 61.94  ? 312 LYS E N    1 
ATOM   6883  C  CA   . LYS E 1 105 ? 64.718  -58.955 58.703  1.00 61.58  ? 312 LYS E CA   1 
ATOM   6884  C  C    . LYS E 1 105 ? 63.766  -58.620 59.847  1.00 72.02  ? 312 LYS E C    1 
ATOM   6885  O  O    . LYS E 1 105 ? 63.069  -57.602 59.819  1.00 70.43  ? 312 LYS E O    1 
ATOM   6886  N  N    . GLY E 1 106 ? 63.667  -59.513 60.828  1.00 71.74  ? 313 GLY E N    1 
ATOM   6887  C  CA   . GLY E 1 106 ? 62.813  -59.256 62.003  1.00 66.57  ? 313 GLY E CA   1 
ATOM   6888  C  C    . GLY E 1 106 ? 61.338  -59.487 61.744  1.00 73.63  ? 313 GLY E C    1 
ATOM   6889  O  O    . GLY E 1 106 ? 60.533  -59.087 62.596  1.00 78.93  ? 313 GLY E O    1 
ATOM   6890  N  N    . THR E 1 107 ? 60.988  -60.101 60.617  1.00 67.49  ? 314 THR E N    1 
ATOM   6891  C  CA   . THR E 1 107 ? 59.590  -60.297 60.272  1.00 67.49  ? 314 THR E CA   1 
ATOM   6892  C  C    . THR E 1 107 ? 59.363  -61.780 60.037  1.00 70.68  ? 314 THR E C    1 
ATOM   6893  O  O    . THR E 1 107 ? 60.306  -62.575 60.027  1.00 74.65  ? 314 THR E O    1 
ATOM   6894  C  CB   . THR E 1 107 ? 59.190  -59.490 59.027  1.00 72.56  ? 314 THR E CB   1 
ATOM   6895  O  OG1  . THR E 1 107 ? 59.632  -60.179 57.842  1.00 74.48  ? 314 THR E OG1  1 
ATOM   6896  C  CG2  . THR E 1 107 ? 59.801  -58.080 59.062  1.00 66.23  ? 314 THR E CG2  1 
ATOM   6897  N  N    . CYS E 1 108 ? 58.100  -62.161 59.840  1.00 65.81  ? 315 CYS E N    1 
ATOM   6898  C  CA   . CYS E 1 108 ? 57.796  -63.582 59.695  1.00 71.88  ? 315 CYS E CA   1 
ATOM   6899  C  C    . CYS E 1 108 ? 58.418  -64.207 58.447  1.00 70.51  ? 315 CYS E C    1 
ATOM   6900  O  O    . CYS E 1 108 ? 58.476  -65.439 58.358  1.00 69.73  ? 315 CYS E O    1 
ATOM   6901  C  CB   . CYS E 1 108 ? 56.278  -63.796 59.689  1.00 76.77  ? 315 CYS E CB   1 
ATOM   6902  S  SG   . CYS E 1 108 ? 55.443  -63.240 58.169  1.00 85.14  ? 315 CYS E SG   1 
ATOM   6903  N  N    . VAL E 1 109 ? 58.897  -63.405 57.497  1.00 70.80  ? 316 VAL E N    1 
ATOM   6904  C  CA   . VAL E 1 109 ? 59.481  -63.923 56.263  1.00 68.60  ? 316 VAL E CA   1 
ATOM   6905  C  C    . VAL E 1 109 ? 60.973  -63.597 56.172  1.00 65.14  ? 316 VAL E C    1 
ATOM   6906  O  O    . VAL E 1 109 ? 61.563  -63.660 55.090  1.00 65.63  ? 316 VAL E O    1 
ATOM   6907  C  CB   . VAL E 1 109 ? 58.725  -63.415 55.021  1.00 64.98  ? 316 VAL E CB   1 
ATOM   6908  C  CG1  . VAL E 1 109 ? 57.343  -64.033 54.942  1.00 63.24  ? 316 VAL E CG1  1 
ATOM   6909  C  CG2  . VAL E 1 109 ? 58.649  -61.889 55.011  1.00 65.33  ? 316 VAL E CG2  1 
ATOM   6910  N  N    . GLU E 1 110 ? 61.592  -63.237 57.285  1.00 62.83  ? 317 GLU E N    1 
ATOM   6911  C  CA   . GLU E 1 110 ? 63.034  -63.060 57.299  1.00 66.47  ? 317 GLU E CA   1 
ATOM   6912  C  C    . GLU E 1 110 ? 63.728  -64.282 56.708  1.00 63.29  ? 317 GLU E C    1 
ATOM   6913  O  O    . GLU E 1 110 ? 63.241  -65.409 56.808  1.00 59.83  ? 317 GLU E O    1 
ATOM   6914  C  CB   . GLU E 1 110 ? 63.502  -62.819 58.725  1.00 63.65  ? 317 GLU E CB   1 
ATOM   6915  C  CG   . GLU E 1 110 ? 64.976  -62.941 58.945  1.00 65.34  ? 317 GLU E CG   1 
ATOM   6916  C  CD   . GLU E 1 110 ? 65.340  -62.450 60.321  1.00 64.70  ? 317 GLU E CD   1 
ATOM   6917  O  OE1  . GLU E 1 110 ? 66.529  -62.217 60.584  1.00 66.71  ? 317 GLU E OE1  1 
ATOM   6918  O  OE2  . GLU E 1 110 ? 64.413  -62.281 61.136  1.00 72.71  ? 317 GLU E OE2  1 
ATOM   6919  N  N    . GLY E 1 111 ? 64.849  -64.046 56.040  1.00 59.45  ? 318 GLY E N    1 
ATOM   6920  C  CA   . GLY E 1 111 ? 65.608  -65.133 55.469  1.00 60.04  ? 318 GLY E CA   1 
ATOM   6921  C  C    . GLY E 1 111 ? 65.128  -65.641 54.130  1.00 61.85  ? 318 GLY E C    1 
ATOM   6922  O  O    . GLY E 1 111 ? 65.795  -66.505 53.554  1.00 63.24  ? 318 GLY E O    1 
ATOM   6923  N  N    . THR E 1 112 ? 64.009  -65.129 53.605  1.00 57.59  ? 319 THR E N    1 
ATOM   6924  C  CA   . THR E 1 112 ? 63.449  -65.670 52.368  1.00 53.29  ? 319 THR E CA   1 
ATOM   6925  C  C    . THR E 1 112 ? 64.409  -65.504 51.199  1.00 57.83  ? 319 THR E C    1 
ATOM   6926  O  O    . THR E 1 112 ? 64.660  -66.453 50.441  1.00 57.34  ? 319 THR E O    1 
ATOM   6927  C  CB   . THR E 1 112 ? 62.122  -64.992 52.044  1.00 59.04  ? 319 THR E CB   1 
ATOM   6928  O  OG1  . THR E 1 112 ? 61.185  -65.259 53.094  1.00 63.04  ? 319 THR E OG1  1 
ATOM   6929  C  CG2  . THR E 1 112 ? 61.567  -65.541 50.734  1.00 54.57  ? 319 THR E CG2  1 
ATOM   6930  N  N    . ILE E 1 113 ? 64.953  -64.300 51.028  1.00 58.08  ? 320 ILE E N    1 
ATOM   6931  C  CA   . ILE E 1 113 ? 65.877  -64.061 49.920  1.00 50.35  ? 320 ILE E CA   1 
ATOM   6932  C  C    . ILE E 1 113 ? 67.112  -64.943 50.032  1.00 53.44  ? 320 ILE E C    1 
ATOM   6933  O  O    . ILE E 1 113 ? 67.456  -65.616 49.043  1.00 52.42  ? 320 ILE E O    1 
ATOM   6934  C  CB   . ILE E 1 113 ? 66.198  -62.565 49.817  1.00 50.78  ? 320 ILE E CB   1 
ATOM   6935  C  CG1  . ILE E 1 113 ? 64.920  -61.799 49.428  1.00 49.72  ? 320 ILE E CG1  1 
ATOM   6936  C  CG2  . ILE E 1 113 ? 67.383  -62.329 48.884  1.00 45.88  ? 320 ILE E CG2  1 
ATOM   6937  C  CD1  . ILE E 1 113 ? 65.153  -60.450 48.831  1.00 56.00  ? 320 ILE E CD1  1 
ATOM   6938  N  N    . PRO E 1 114 ? 67.804  -65.021 51.174  1.00 54.70  ? 321 PRO E N    1 
ATOM   6939  C  CA   . PRO E 1 114 ? 68.917  -65.980 51.293  1.00 55.40  ? 321 PRO E CA   1 
ATOM   6940  C  C    . PRO E 1 114 ? 68.552  -67.424 50.976  1.00 54.87  ? 321 PRO E C    1 
ATOM   6941  O  O    . PRO E 1 114 ? 69.324  -68.098 50.284  1.00 54.40  ? 321 PRO E O    1 
ATOM   6942  C  CB   . PRO E 1 114 ? 69.343  -65.819 52.757  1.00 53.56  ? 321 PRO E CB   1 
ATOM   6943  C  CG   . PRO E 1 114 ? 69.032  -64.436 53.061  1.00 55.64  ? 321 PRO E CG   1 
ATOM   6944  C  CD   . PRO E 1 114 ? 67.749  -64.131 52.340  1.00 54.14  ? 321 PRO E CD   1 
ATOM   6945  N  N    . LYS E 1 115 ? 67.404  -67.916 51.463  1.00 55.39  ? 322 LYS E N    1 
ATOM   6946  C  CA   . LYS E 1 115 ? 66.997  -69.298 51.198  1.00 58.48  ? 322 LYS E CA   1 
ATOM   6947  C  C    . LYS E 1 115 ? 66.818  -69.544 49.703  1.00 56.52  ? 322 LYS E C    1 
ATOM   6948  O  O    . LYS E 1 115 ? 67.189  -70.606 49.190  1.00 54.35  ? 322 LYS E O    1 
ATOM   6949  C  CB   . LYS E 1 115 ? 65.705  -69.607 51.965  1.00 65.92  ? 322 LYS E CB   1 
ATOM   6950  C  CG   . LYS E 1 115 ? 65.068  -70.956 51.687  1.00 60.26  ? 322 LYS E CG   1 
ATOM   6951  N  N    . LEU E 1 116 ? 66.302  -68.546 48.981  1.00 56.22  ? 323 LEU E N    1 
ATOM   6952  C  CA   . LEU E 1 116 ? 66.066  -68.666 47.548  1.00 50.71  ? 323 LEU E CA   1 
ATOM   6953  C  C    . LEU E 1 116 ? 67.341  -68.521 46.722  1.00 54.72  ? 323 LEU E C    1 
ATOM   6954  O  O    . LEU E 1 116 ? 67.533  -69.262 45.752  1.00 59.32  ? 323 LEU E O    1 
ATOM   6955  C  CB   . LEU E 1 116 ? 65.048  -67.615 47.100  1.00 49.30  ? 323 LEU E CB   1 
ATOM   6956  C  CG   . LEU E 1 116 ? 63.559  -67.835 47.416  1.00 53.63  ? 323 LEU E CG   1 
ATOM   6957  C  CD1  . LEU E 1 116 ? 62.705  -66.716 46.810  1.00 54.18  ? 323 LEU E CD1  1 
ATOM   6958  C  CD2  . LEU E 1 116 ? 63.101  -69.196 46.887  1.00 54.94  ? 323 LEU E CD2  1 
ATOM   6959  N  N    . PHE E 1 117 ? 68.213  -67.561 47.050  1.00 53.75  ? 324 PHE E N    1 
ATOM   6960  C  CA   . PHE E 1 117 ? 69.223  -67.125 46.087  1.00 53.31  ? 324 PHE E CA   1 
ATOM   6961  C  C    . PHE E 1 117 ? 70.664  -67.286 46.528  1.00 49.29  ? 324 PHE E C    1 
ATOM   6962  O  O    . PHE E 1 117 ? 71.562  -67.106 45.699  1.00 45.80  ? 324 PHE E O    1 
ATOM   6963  C  CB   . PHE E 1 117 ? 69.039  -65.648 45.719  1.00 50.15  ? 324 PHE E CB   1 
ATOM   6964  C  CG   . PHE E 1 117 ? 67.699  -65.309 45.131  1.00 52.70  ? 324 PHE E CG   1 
ATOM   6965  C  CD1  . PHE E 1 117 ? 67.394  -65.637 43.815  1.00 53.66  ? 324 PHE E CD1  1 
ATOM   6966  C  CD2  . PHE E 1 117 ? 66.765  -64.605 45.878  1.00 49.44  ? 324 PHE E CD2  1 
ATOM   6967  C  CE1  . PHE E 1 117 ? 66.165  -65.286 43.258  1.00 53.64  ? 324 PHE E CE1  1 
ATOM   6968  C  CE2  . PHE E 1 117 ? 65.547  -64.242 45.328  1.00 51.25  ? 324 PHE E CE2  1 
ATOM   6969  C  CZ   . PHE E 1 117 ? 65.242  -64.590 44.016  1.00 55.80  ? 324 PHE E CZ   1 
ATOM   6970  N  N    . ARG E 1 118 ? 70.924  -67.631 47.774  1.00 48.55  ? 325 ARG E N    1 
ATOM   6971  C  CA   . ARG E 1 118 ? 72.272  -67.555 48.303  1.00 50.62  ? 325 ARG E CA   1 
ATOM   6972  C  C    . ARG E 1 118 ? 72.914  -68.933 48.295  1.00 55.39  ? 325 ARG E C    1 
ATOM   6973  O  O    . ARG E 1 118 ? 72.296  -69.914 48.710  1.00 56.55  ? 325 ARG E O    1 
ATOM   6974  C  CB   . ARG E 1 118 ? 72.259  -66.971 49.714  1.00 51.38  ? 325 ARG E CB   1 
ATOM   6975  C  CG   . ARG E 1 118 ? 73.640  -66.755 50.321  1.00 52.04  ? 325 ARG E CG   1 
ATOM   6976  C  CD   . ARG E 1 118 ? 73.685  -67.399 51.686  1.00 52.22  ? 325 ARG E CD   1 
ATOM   6977  N  NE   . ARG E 1 118 ? 73.158  -66.511 52.714  1.00 53.93  ? 325 ARG E NE   1 
ATOM   6978  C  CZ   . ARG E 1 118 ? 72.749  -66.911 53.915  1.00 63.28  ? 325 ARG E CZ   1 
ATOM   6979  N  NH1  . ARG E 1 118 ? 72.775  -68.202 54.251  1.00 58.36  ? 325 ARG E NH1  1 
ATOM   6980  N  NH2  . ARG E 1 118 ? 72.302  -66.012 54.783  1.00 67.81  ? 325 ARG E NH2  1 
ATOM   6981  N  N    . GLY E 1 119 ? 74.151  -69.006 47.805  1.00 49.74  ? 326 GLY E N    1 
ATOM   6982  C  CA   . GLY E 1 119 ? 74.952  -70.200 47.909  1.00 49.46  ? 326 GLY E CA   1 
ATOM   6983  C  C    . GLY E 1 119 ? 76.285  -69.919 48.577  1.00 47.32  ? 326 GLY E C    1 
ATOM   6984  O  O    . GLY E 1 119 ? 76.567  -68.804 49.019  1.00 53.62  ? 326 GLY E O    1 
ATOM   6985  N  N    . LYS E 1 120 ? 77.117  -70.958 48.616  1.00 54.20  ? 327 LYS E N    1 
ATOM   6986  C  CA   . LYS E 1 120 ? 78.441  -70.884 49.227  1.00 53.82  ? 327 LYS E CA   1 
ATOM   6987  C  C    . LYS E 1 120 ? 79.471  -71.522 48.296  1.00 51.51  ? 327 LYS E C    1 
ATOM   6988  O  O    . LYS E 1 120 ? 79.234  -72.609 47.765  1.00 49.72  ? 327 LYS E O    1 
ATOM   6989  C  CB   . LYS E 1 120 ? 78.425  -71.564 50.615  1.00 49.43  ? 327 LYS E CB   1 
ATOM   6990  C  CG   . LYS E 1 120 ? 79.667  -71.273 51.500  1.00 56.18  ? 327 LYS E CG   1 
ATOM   6991  C  CD   . LYS E 1 120 ? 79.284  -70.887 52.921  1.00 56.90  ? 327 LYS E CD   1 
ATOM   6992  N  N    . MET E 1 121 ? 80.553  -70.787 48.063  1.00 53.68  ? 328 MET E N    1 
ATOM   6993  C  CA   . MET E 1 121 ? 81.661  -71.283 47.218  1.00 54.53  ? 328 MET E CA   1 
ATOM   6994  C  C    . MET E 1 121 ? 82.929  -71.335 48.072  1.00 58.29  ? 328 MET E C    1 
ATOM   6995  O  O    . MET E 1 121 ? 82.952  -70.717 49.141  1.00 57.81  ? 328 MET E O    1 
ATOM   6996  C  CB   . MET E 1 121 ? 81.886  -70.368 46.012  1.00 52.86  ? 328 MET E CB   1 
ATOM   6997  C  CG   . MET E 1 121 ? 82.313  -68.958 46.351  1.00 58.91  ? 328 MET E CG   1 
ATOM   6998  S  SD   . MET E 1 121 ? 82.297  -67.883 44.900  1.00 68.03  ? 328 MET E SD   1 
ATOM   6999  C  CE   . MET E 1 121 ? 83.794  -66.942 45.183  1.00 53.14  ? 328 MET E CE   1 
ATOM   7000  N  N    . VAL E 1 122 ? 83.933  -72.080 47.619  1.00 57.25  ? 329 VAL E N    1 
ATOM   7001  C  CA   . VAL E 1 122 ? 85.201  -72.212 48.387  1.00 54.91  ? 329 VAL E CA   1 
ATOM   7002  C  C    . VAL E 1 122 ? 86.381  -71.954 47.455  1.00 51.96  ? 329 VAL E C    1 
ATOM   7003  O  O    . VAL E 1 122 ? 86.462  -72.586 46.408  1.00 54.38  ? 329 VAL E O    1 
ATOM   7004  C  CB   . VAL E 1 122 ? 85.299  -73.561 49.129  1.00 58.76  ? 329 VAL E CB   1 
ATOM   7005  C  CG1  . VAL E 1 122 ? 85.073  -74.762 48.226  1.00 59.12  ? 329 VAL E CG1  1 
ATOM   7006  C  CG2  . VAL E 1 122 ? 86.577  -73.691 49.938  1.00 57.73  ? 329 VAL E CG2  1 
ATOM   7007  N  N    . SER E 1 123 ? 87.230  -71.007 47.832  1.00 58.44  ? 330 SER E N    1 
ATOM   7008  C  CA   . SER E 1 123 ? 88.441  -70.689 47.045  1.00 55.26  ? 330 SER E CA   1 
ATOM   7009  C  C    . SER E 1 123 ? 89.644  -71.282 47.768  1.00 56.65  ? 330 SER E C    1 
ATOM   7010  O  O    . SER E 1 123 ? 89.818  -70.986 48.955  1.00 58.37  ? 330 SER E O    1 
ATOM   7011  C  CB   . SER E 1 123 ? 88.589  -69.211 46.885  1.00 55.29  ? 330 SER E CB   1 
ATOM   7012  O  OG   . SER E 1 123 ? 87.459  -68.641 46.246  1.00 61.60  ? 330 SER E OG   1 
ATOM   7013  N  N    . TYR E 1 124 ? 90.427  -72.095 47.070  1.00 51.95  ? 331 TYR E N    1 
ATOM   7014  C  CA   . TYR E 1 124 ? 91.602  -72.746 47.689  1.00 57.48  ? 331 TYR E CA   1 
ATOM   7015  C  C    . TYR E 1 124 ? 92.885  -72.107 47.171  1.00 54.01  ? 331 TYR E C    1 
ATOM   7016  O  O    . TYR E 1 124 ? 92.953  -71.845 45.990  1.00 55.78  ? 331 TYR E O    1 
ATOM   7017  C  CB   . TYR E 1 124 ? 91.629  -74.239 47.373  1.00 52.73  ? 331 TYR E CB   1 
ATOM   7018  C  CG   . TYR E 1 124 ? 90.429  -75.047 47.790  1.00 54.78  ? 331 TYR E CG   1 
ATOM   7019  C  CD1  . TYR E 1 124 ? 90.354  -75.596 49.055  1.00 58.72  ? 331 TYR E CD1  1 
ATOM   7020  C  CD2  . TYR E 1 124 ? 89.399  -75.314 46.905  1.00 54.98  ? 331 TYR E CD2  1 
ATOM   7021  C  CE1  . TYR E 1 124 ? 89.269  -76.356 49.452  1.00 55.59  ? 331 TYR E CE1  1 
ATOM   7022  C  CE2  . TYR E 1 124 ? 88.306  -76.073 47.284  1.00 62.93  ? 331 TYR E CE2  1 
ATOM   7023  C  CZ   . TYR E 1 124 ? 88.242  -76.598 48.562  1.00 68.24  ? 331 TYR E CZ   1 
ATOM   7024  O  OH   . TYR E 1 124 ? 87.173  -77.349 48.954  1.00 65.40  ? 331 TYR E OH   1 
ATOM   7025  N  N    . ILE E 1 125 ? 93.847  -71.843 48.047  1.00 50.75  ? 332 ILE E N    1 
ATOM   7026  C  CA   . ILE E 1 125 ? 95.147  -71.304 47.671  1.00 50.43  ? 332 ILE E CA   1 
ATOM   7027  C  C    . ILE E 1 125 ? 96.203  -72.336 48.036  1.00 58.04  ? 332 ILE E C    1 
ATOM   7028  O  O    . ILE E 1 125 ? 96.221  -72.826 49.171  1.00 59.63  ? 332 ILE E O    1 
ATOM   7029  C  CB   . ILE E 1 125 ? 95.462  -69.981 48.393  1.00 54.98  ? 332 ILE E CB   1 
ATOM   7030  C  CG1  . ILE E 1 125 ? 94.249  -69.028 48.435  1.00 56.09  ? 332 ILE E CG1  1 
ATOM   7031  C  CG2  . ILE E 1 125 ? 96.704  -69.362 47.790  1.00 55.96  ? 332 ILE E CG2  1 
ATOM   7032  C  CD1  . ILE E 1 125 ? 93.746  -68.528 47.052  1.00 51.84  ? 332 ILE E CD1  1 
ATOM   7033  N  N    . GLN E 1 126 ? 97.110  -72.627 47.104  1.00 56.13  ? 333 GLN E N    1 
ATOM   7034  C  CA   . GLN E 1 126 ? 98.133  -73.654 47.310  1.00 55.85  ? 333 GLN E CA   1 
ATOM   7035  C  C    . GLN E 1 126 ? 99.472  -73.183 46.746  1.00 52.68  ? 333 GLN E C    1 
ATOM   7036  O  O    . GLN E 1 126 ? 99.624  -73.051 45.523  1.00 51.87  ? 333 GLN E O    1 
ATOM   7037  C  CB   . GLN E 1 126 ? 97.694  -74.961 46.660  1.00 52.17  ? 333 GLN E CB   1 
ATOM   7038  C  CG   . GLN E 1 126 ? 98.816  -75.945 46.455  1.00 61.96  ? 333 GLN E CG   1 
ATOM   7039  C  CD   . GLN E 1 126 ? 99.287  -76.536 47.749  1.00 58.44  ? 333 GLN E CD   1 
ATOM   7040  O  OE1  . GLN E 1 126 ? 98.602  -77.378 48.331  1.00 62.42  ? 333 GLN E OE1  1 
ATOM   7041  N  NE2  . GLN E 1 126 ? 100.459 -76.098 48.217  1.00 58.06  ? 333 GLN E NE2  1 
ATOM   7042  N  N    . CYS E 1 127 ? 100.445 -72.924 47.621  1.00 54.27  ? 334 CYS E N    1 
ATOM   7043  C  CA   . CYS E 1 127 ? 101.754 -72.469 47.146  1.00 57.30  ? 334 CYS E CA   1 
ATOM   7044  C  C    . CYS E 1 127 ? 102.503 -73.579 46.426  1.00 57.72  ? 334 CYS E C    1 
ATOM   7045  O  O    . CYS E 1 127 ? 102.454 -74.746 46.824  1.00 52.13  ? 334 CYS E O    1 
ATOM   7046  C  CB   . CYS E 1 127 ? 102.634 -71.976 48.288  1.00 54.53  ? 334 CYS E CB   1 
ATOM   7047  S  SG   . CYS E 1 127 ? 101.997 -70.616 49.169  1.00 57.13  ? 334 CYS E SG   1 
ATOM   7048  N  N    . LYS E 1 128 ? 103.276 -73.204 45.419  1.00 62.33  ? 335 LYS E N    1 
ATOM   7049  C  CA   . LYS E 1 128 ? 103.997 -74.210 44.609  1.00 63.48  ? 335 LYS E CA   1 
ATOM   7050  C  C    . LYS E 1 128 ? 105.364 -74.536 45.213  1.00 62.67  ? 335 LYS E C    1 
ATOM   7051  O  O    . LYS E 1 128 ? 105.636 -75.724 45.396  1.00 67.32  ? 335 LYS E O    1 
ATOM   7052  C  CB   . LYS E 1 128 ? 104.132 -73.666 43.187  1.00 63.52  ? 335 LYS E CB   1 
ATOM   7053  C  CG   . LYS E 1 128 ? 102.846 -73.157 42.557  1.00 59.76  ? 335 LYS E CG   1 
ATOM   7054  C  CD   . LYS E 1 128 ? 103.092 -72.419 41.265  1.00 64.02  ? 335 LYS E CD   1 
ATOM   7055  C  CE   . LYS E 1 128 ? 103.587 -73.327 40.161  1.00 59.78  ? 335 LYS E CE   1 
ATOM   7056  N  NZ   . LYS E 1 128 ? 102.534 -74.273 39.722  1.00 66.89  ? 335 LYS E NZ   1 
ATOM   7057  N  N    . GLU E 1 129 ? 106.183 -73.532 45.515  1.00 64.03  ? 336 GLU E N    1 
ATOM   7058  C  CA   . GLU E 1 129 ? 107.546 -73.776 45.983  1.00 64.83  ? 336 GLU E CA   1 
ATOM   7059  C  C    . GLU E 1 129 ? 107.666 -74.012 47.490  1.00 64.82  ? 336 GLU E C    1 
ATOM   7060  O  O    . GLU E 1 129 ? 108.745 -74.390 47.957  1.00 65.34  ? 336 GLU E O    1 
ATOM   7061  C  CB   . GLU E 1 129 ? 108.446 -72.595 45.596  1.00 65.26  ? 336 GLU E CB   1 
ATOM   7062  C  CG   . GLU E 1 129 ? 109.068 -72.702 44.223  1.00 74.61  ? 336 GLU E CG   1 
ATOM   7063  C  CD   . GLU E 1 129 ? 110.560 -72.371 44.229  1.00 85.90  ? 336 GLU E CD   1 
ATOM   7064  O  OE1  . GLU E 1 129 ? 111.268 -72.865 45.141  1.00 92.11  ? 336 GLU E OE1  1 
ATOM   7065  O  OE2  . GLU E 1 129 ? 111.025 -71.636 43.322  1.00 82.68  ? 336 GLU E OE2  1 
ATOM   7066  N  N    . VAL E 1 130 ? 106.613 -73.795 48.278  1.00 63.02  ? 337 VAL E N    1 
ATOM   7067  C  CA   . VAL E 1 130 ? 106.724 -73.869 49.731  1.00 57.75  ? 337 VAL E CA   1 
ATOM   7068  C  C    . VAL E 1 130 ? 105.437 -74.476 50.281  1.00 61.00  ? 337 VAL E C    1 
ATOM   7069  O  O    . VAL E 1 130 ? 104.436 -74.609 49.575  1.00 65.86  ? 337 VAL E O    1 
ATOM   7070  C  CB   . VAL E 1 130 ? 107.049 -72.478 50.342  1.00 62.93  ? 337 VAL E CB   1 
ATOM   7071  C  CG1  . VAL E 1 130 ? 105.820 -71.591 50.435  1.00 61.55  ? 337 VAL E CG1  1 
ATOM   7072  C  CG2  . VAL E 1 130 ? 107.720 -72.625 51.664  1.00 68.34  ? 337 VAL E CG2  1 
ATOM   7073  N  N    . ASP E 1 131 ? 105.483 -74.930 51.532  1.00 65.56  ? 338 ASP E N    1 
ATOM   7074  C  CA   . ASP E 1 131 ? 104.390 -75.766 52.045  1.00 68.03  ? 338 ASP E CA   1 
ATOM   7075  C  C    . ASP E 1 131 ? 103.381 -74.896 52.790  1.00 70.29  ? 338 ASP E C    1 
ATOM   7076  O  O    . ASP E 1 131 ? 103.351 -74.825 54.023  1.00 70.08  ? 338 ASP E O    1 
ATOM   7077  C  CB   . ASP E 1 131 ? 104.922 -76.877 52.939  1.00 71.44  ? 338 ASP E CB   1 
ATOM   7078  C  CG   . ASP E 1 131 ? 103.854 -77.891 53.284  1.00 77.10  ? 338 ASP E CG   1 
ATOM   7079  O  OD1  . ASP E 1 131 ? 102.709 -77.729 52.804  1.00 76.41  ? 338 ASP E OD1  1 
ATOM   7080  O  OD2  . ASP E 1 131 ? 104.148 -78.845 54.036  1.00 86.51  ? 338 ASP E OD2  1 
ATOM   7081  N  N    . TYR E 1 132 ? 102.503 -74.259 52.022  1.00 65.06  ? 339 TYR E N    1 
ATOM   7082  C  CA   . TYR E 1 132 ? 101.544 -73.333 52.607  1.00 56.64  ? 339 TYR E CA   1 
ATOM   7083  C  C    . TYR E 1 132 ? 100.246 -73.381 51.812  1.00 56.21  ? 339 TYR E C    1 
ATOM   7084  O  O    . TYR E 1 132 ? 100.242 -73.159 50.595  1.00 57.57  ? 339 TYR E O    1 
ATOM   7085  C  CB   . TYR E 1 132 ? 102.137 -71.928 52.625  1.00 61.25  ? 339 TYR E CB   1 
ATOM   7086  C  CG   . TYR E 1 132 ? 101.336 -70.894 53.396  1.00 59.66  ? 339 TYR E CG   1 
ATOM   7087  C  CD1  . TYR E 1 132 ? 100.369 -70.114 52.754  1.00 56.50  ? 339 TYR E CD1  1 
ATOM   7088  C  CD2  . TYR E 1 132 ? 101.570 -70.677 54.746  1.00 58.68  ? 339 TYR E CD2  1 
ATOM   7089  C  CE1  . TYR E 1 132 ? 99.662  -69.159 53.443  1.00 61.17  ? 339 TYR E CE1  1 
ATOM   7090  C  CE2  . TYR E 1 132 ? 100.865 -69.724 55.448  1.00 62.54  ? 339 TYR E CE2  1 
ATOM   7091  C  CZ   . TYR E 1 132 ? 99.910  -68.968 54.794  1.00 66.67  ? 339 TYR E CZ   1 
ATOM   7092  O  OH   . TYR E 1 132 ? 99.205  -68.014 55.489  1.00 71.38  ? 339 TYR E OH   1 
ATOM   7093  N  N    . ARG E 1 133 ? 99.151  -73.670 52.506  1.00 51.00  ? 340 ARG E N    1 
ATOM   7094  C  CA   . ARG E 1 133 ? 97.831  -73.806 51.914  1.00 56.66  ? 340 ARG E CA   1 
ATOM   7095  C  C    . ARG E 1 133 ? 96.844  -72.949 52.706  1.00 57.46  ? 340 ARG E C    1 
ATOM   7096  O  O    . ARG E 1 133 ? 97.013  -72.752 53.913  1.00 55.36  ? 340 ARG E O    1 
ATOM   7097  C  CB   . ARG E 1 133 ? 97.434  -75.283 51.915  1.00 60.31  ? 340 ARG E CB   1 
ATOM   7098  C  CG   . ARG E 1 133 ? 96.211  -75.641 51.130  1.00 59.95  ? 340 ARG E CG   1 
ATOM   7099  C  CD   . ARG E 1 133 ? 95.931  -77.133 51.279  1.00 63.57  ? 340 ARG E CD   1 
ATOM   7100  N  NE   . ARG E 1 133 ? 97.060  -77.962 50.846  1.00 68.72  ? 340 ARG E NE   1 
ATOM   7101  C  CZ   . ARG E 1 133 ? 97.810  -78.731 51.643  1.00 73.87  ? 340 ARG E CZ   1 
ATOM   7102  N  NH1  . ARG E 1 133 ? 97.569  -78.810 52.968  1.00 61.74  ? 340 ARG E NH1  1 
ATOM   7103  N  NH2  . ARG E 1 133 ? 98.814  -79.431 51.101  1.00 66.88  ? 340 ARG E NH2  1 
ATOM   7104  N  N    . SER E 1 134 ? 95.829  -72.415 52.022  1.00 56.99  ? 341 SER E N    1 
ATOM   7105  C  CA   . SER E 1 134 ? 94.758  -71.644 52.702  1.00 54.48  ? 341 SER E CA   1 
ATOM   7106  C  C    . SER E 1 134 ? 93.423  -71.893 52.005  1.00 56.99  ? 341 SER E C    1 
ATOM   7107  O  O    . SER E 1 134 ? 93.430  -72.279 50.836  1.00 60.11  ? 341 SER E O    1 
ATOM   7108  C  CB   . SER E 1 134 ? 95.061  -70.183 52.737  1.00 56.36  ? 341 SER E CB   1 
ATOM   7109  O  OG   . SER E 1 134 ? 94.430  -69.564 53.844  1.00 61.56  ? 341 SER E OG   1 
ATOM   7110  N  N    . ASP E 1 135 ? 92.321  -71.694 52.720  1.00 61.85  ? 342 ASP E N    1 
ATOM   7111  C  CA   . ASP E 1 135 ? 90.981  -71.825 52.098  1.00 59.93  ? 342 ASP E CA   1 
ATOM   7112  C  C    . ASP E 1 135 ? 90.078  -70.719 52.647  1.00 56.39  ? 342 ASP E C    1 
ATOM   7113  O  O    . ASP E 1 135 ? 90.337  -70.240 53.752  1.00 62.77  ? 342 ASP E O    1 
ATOM   7114  C  CB   . ASP E 1 135 ? 90.392  -73.232 52.247  1.00 69.70  ? 342 ASP E CB   1 
ATOM   7115  C  CG   . ASP E 1 135 ? 90.642  -73.904 53.582  1.00 65.30  ? 342 ASP E CG   1 
ATOM   7116  O  OD1  . ASP E 1 135 ? 91.109  -75.052 53.568  1.00 64.93  ? 342 ASP E OD1  1 
ATOM   7117  O  OD2  . ASP E 1 135 ? 90.346  -73.288 54.619  1.00 75.05  ? 342 ASP E OD2  1 
ATOM   7118  N  N    . ARG E 1 136 ? 89.068  -70.330 51.880  1.00 55.66  ? 343 ARG E N    1 
ATOM   7119  C  CA   . ARG E 1 136 ? 88.121  -69.274 52.303  1.00 56.21  ? 343 ARG E CA   1 
ATOM   7120  C  C    . ARG E 1 136 ? 86.749  -69.614 51.730  1.00 55.22  ? 343 ARG E C    1 
ATOM   7121  O  O    . ARG E 1 136 ? 86.652  -69.836 50.518  1.00 57.22  ? 343 ARG E O    1 
ATOM   7122  C  CB   . ARG E 1 136 ? 88.602  -67.907 51.814  1.00 52.27  ? 343 ARG E CB   1 
ATOM   7123  C  CG   . ARG E 1 136 ? 87.582  -66.783 51.887  1.00 54.49  ? 343 ARG E CG   1 
ATOM   7124  C  CD   . ARG E 1 136 ? 87.460  -66.184 53.269  1.00 57.05  ? 343 ARG E CD   1 
ATOM   7125  N  NE   . ARG E 1 136 ? 88.639  -65.438 53.674  1.00 56.73  ? 343 ARG E NE   1 
ATOM   7126  C  CZ   . ARG E 1 136 ? 89.249  -65.602 54.838  1.00 60.63  ? 343 ARG E CZ   1 
ATOM   7127  N  NH1  . ARG E 1 136 ? 88.806  -66.503 55.695  1.00 63.34  ? 343 ARG E NH1  1 
ATOM   7128  N  NH2  . ARG E 1 136 ? 90.326  -64.900 55.132  1.00 57.76  ? 343 ARG E NH2  1 
ATOM   7129  N  N    . ARG E 1 137 ? 85.733  -69.635 52.585  1.00 57.96  ? 344 ARG E N    1 
ATOM   7130  C  CA   . ARG E 1 137 ? 84.358  -69.939 52.120  1.00 56.12  ? 344 ARG E CA   1 
ATOM   7131  C  C    . ARG E 1 137 ? 83.536  -68.649 52.075  1.00 55.42  ? 344 ARG E C    1 
ATOM   7132  O  O    . ARG E 1 137 ? 83.421  -67.999 53.115  1.00 58.70  ? 344 ARG E O    1 
ATOM   7133  C  CB   . ARG E 1 137 ? 83.728  -70.997 53.026  1.00 51.67  ? 344 ARG E CB   1 
ATOM   7134  C  CG   . ARG E 1 137 ? 84.213  -72.409 52.746  1.00 52.01  ? 344 ARG E CG   1 
ATOM   7135  C  CD   . ARG E 1 137 ? 84.569  -73.183 53.997  1.00 58.72  ? 344 ARG E CD   1 
ATOM   7136  N  NE   . ARG E 1 137 ? 85.312  -74.387 53.662  1.00 50.55  ? 344 ARG E NE   1 
ATOM   7137  C  CZ   . ARG E 1 137 ? 86.621  -74.530 53.810  1.00 58.01  ? 344 ARG E CZ   1 
ATOM   7138  N  NH1  . ARG E 1 137 ? 87.203  -75.664 53.467  1.00 48.40  ? 344 ARG E NH1  1 
ATOM   7139  N  NH2  . ARG E 1 137 ? 87.345  -73.541 54.298  1.00 56.39  ? 344 ARG E NH2  1 
ATOM   7140  N  N    . GLU E 1 138 ? 82.982  -68.350 50.902  1.00 54.81  ? 345 GLU E N    1 
ATOM   7141  C  CA   . GLU E 1 138 ? 82.240  -67.084 50.730  1.00 52.29  ? 345 GLU E CA   1 
ATOM   7142  C  C    . GLU E 1 138 ? 80.866  -67.294 50.118  1.00 50.97  ? 345 GLU E C    1 
ATOM   7143  O  O    . GLU E 1 138 ? 80.721  -68.155 49.255  1.00 55.72  ? 345 GLU E O    1 
ATOM   7144  C  CB   . GLU E 1 138 ? 83.004  -66.114 49.835  1.00 48.54  ? 345 GLU E CB   1 
ATOM   7145  C  CG   . GLU E 1 138 ? 84.380  -65.769 50.347  1.00 51.60  ? 345 GLU E CG   1 
ATOM   7146  C  CD   . GLU E 1 138 ? 85.284  -65.148 49.304  1.00 61.45  ? 345 GLU E CD   1 
ATOM   7147  O  OE1  . GLU E 1 138 ? 85.562  -65.807 48.290  1.00 57.69  ? 345 GLU E OE1  1 
ATOM   7148  O  OE2  . GLU E 1 138 ? 85.698  -64.008 49.514  1.00 58.33  ? 345 GLU E OE2  1 
ATOM   7149  N  N    . ASP E 1 139 ? 79.913  -66.496 50.562  1.00 50.98  ? 346 ASP E N    1 
ATOM   7150  C  CA   . ASP E 1 139 ? 78.562  -66.479 50.046  1.00 51.32  ? 346 ASP E CA   1 
ATOM   7151  C  C    . ASP E 1 139 ? 78.511  -65.747 48.710  1.00 52.50  ? 346 ASP E C    1 
ATOM   7152  O  O    . ASP E 1 139 ? 79.335  -64.886 48.409  1.00 52.84  ? 346 ASP E O    1 
ATOM   7153  C  CB   . ASP E 1 139 ? 77.619  -65.799 51.044  1.00 50.90  ? 346 ASP E CB   1 
ATOM   7154  C  CG   . ASP E 1 139 ? 77.361  -66.647 52.276  1.00 50.65  ? 346 ASP E CG   1 
ATOM   7155  O  OD1  . ASP E 1 139 ? 77.448  -67.880 52.174  1.00 50.15  ? 346 ASP E OD1  1 
ATOM   7156  O  OD2  . ASP E 1 139 ? 77.058  -66.082 53.344  1.00 55.12  ? 346 ASP E OD2  1 
ATOM   7157  N  N    . TYR E 1 140 ? 77.478  -66.107 47.956  1.00 49.86  ? 347 TYR E N    1 
ATOM   7158  C  CA   . TYR E 1 140 ? 77.213  -65.447 46.663  1.00 50.70  ? 347 TYR E CA   1 
ATOM   7159  C  C    . TYR E 1 140 ? 75.702  -65.450 46.462  1.00 55.08  ? 347 TYR E C    1 
ATOM   7160  O  O    . TYR E 1 140 ? 75.040  -66.384 46.919  1.00 54.21  ? 347 TYR E O    1 
ATOM   7161  C  CB   . TYR E 1 140 ? 77.913  -66.158 45.502  1.00 40.08  ? 347 TYR E CB   1 
ATOM   7162  C  CG   . TYR E 1 140 ? 77.455  -67.561 45.206  1.00 46.00  ? 347 TYR E CG   1 
ATOM   7163  C  CD1  . TYR E 1 140 ? 78.122  -68.649 45.739  1.00 47.30  ? 347 TYR E CD1  1 
ATOM   7164  C  CD2  . TYR E 1 140 ? 76.376  -67.802 44.373  1.00 44.51  ? 347 TYR E CD2  1 
ATOM   7165  C  CE1  . TYR E 1 140 ? 77.712  -69.940 45.468  1.00 47.41  ? 347 TYR E CE1  1 
ATOM   7166  C  CE2  . TYR E 1 140 ? 75.939  -69.084 44.109  1.00 40.62  ? 347 TYR E CE2  1 
ATOM   7167  C  CZ   . TYR E 1 140 ? 76.617  -70.153 44.656  1.00 49.34  ? 347 TYR E CZ   1 
ATOM   7168  O  OH   . TYR E 1 140 ? 76.201  -71.416 44.391  1.00 50.36  ? 347 TYR E OH   1 
ATOM   7169  N  N    . TYR E 1 141 ? 75.164  -64.403 45.861  1.00 47.68  ? 348 TYR E N    1 
ATOM   7170  C  CA   . TYR E 1 141 ? 73.755  -64.386 45.489  1.00 47.66  ? 348 TYR E CA   1 
ATOM   7171  C  C    . TYR E 1 141 ? 73.566  -64.520 43.989  1.00 55.47  ? 348 TYR E C    1 
ATOM   7172  O  O    . TYR E 1 141 ? 72.427  -64.492 43.505  1.00 54.97  ? 348 TYR E O    1 
ATOM   7173  C  CB   . TYR E 1 141 ? 73.091  -63.094 45.972  1.00 47.72  ? 348 TYR E CB   1 
ATOM   7174  C  CG   . TYR E 1 141 ? 72.807  -63.102 47.451  1.00 54.38  ? 348 TYR E CG   1 
ATOM   7175  C  CD1  . TYR E 1 141 ? 73.827  -63.273 48.378  1.00 49.41  ? 348 TYR E CD1  1 
ATOM   7176  C  CD2  . TYR E 1 141 ? 71.506  -62.940 47.924  1.00 54.13  ? 348 TYR E CD2  1 
ATOM   7177  C  CE1  . TYR E 1 141 ? 73.552  -63.288 49.737  1.00 51.17  ? 348 TYR E CE1  1 
ATOM   7178  C  CE2  . TYR E 1 141 ? 71.227  -62.949 49.270  1.00 53.30  ? 348 TYR E CE2  1 
ATOM   7179  C  CZ   . TYR E 1 141 ? 72.245  -63.132 50.166  1.00 53.94  ? 348 TYR E CZ   1 
ATOM   7180  O  OH   . TYR E 1 141 ? 71.937  -63.144 51.501  1.00 57.70  ? 348 TYR E OH   1 
ATOM   7181  N  N    . ASP E 1 142 ? 74.656  -64.629 43.241  1.00 52.99  ? 349 ASP E N    1 
ATOM   7182  C  CA   . ASP E 1 142 ? 74.602  -64.762 41.799  1.00 48.07  ? 349 ASP E CA   1 
ATOM   7183  C  C    . ASP E 1 142 ? 75.994  -65.167 41.359  1.00 48.91  ? 349 ASP E C    1 
ATOM   7184  O  O    . ASP E 1 142 ? 76.931  -65.188 42.159  1.00 45.00  ? 349 ASP E O    1 
ATOM   7185  C  CB   . ASP E 1 142 ? 74.112  -63.473 41.127  1.00 51.43  ? 349 ASP E CB   1 
ATOM   7186  C  CG   . ASP E 1 142 ? 75.107  -62.305 41.214  1.00 53.38  ? 349 ASP E CG   1 
ATOM   7187  O  OD1  . ASP E 1 142 ? 76.119  -62.361 41.960  1.00 60.50  ? 349 ASP E OD1  1 
ATOM   7188  O  OD2  . ASP E 1 142 ? 74.854  -61.293 40.525  1.00 46.26  ? 349 ASP E OD2  1 
ATOM   7189  N  N    . ILE E 1 143 ? 76.118  -65.509 40.078  1.00 55.56  ? 350 ILE E N    1 
ATOM   7190  C  CA   . ILE E 1 143 ? 77.356  -66.057 39.531  1.00 52.53  ? 350 ILE E CA   1 
ATOM   7191  C  C    . ILE E 1 143 ? 77.690  -65.326 38.238  1.00 51.35  ? 350 ILE E C    1 
ATOM   7192  O  O    . ILE E 1 143 ? 76.861  -65.261 37.321  1.00 56.01  ? 350 ILE E O    1 
ATOM   7193  C  CB   . ILE E 1 143 ? 77.254  -67.577 39.283  1.00 43.16  ? 350 ILE E CB   1 
ATOM   7194  C  CG1  . ILE E 1 143 ? 76.786  -68.301 40.542  1.00 47.39  ? 350 ILE E CG1  1 
ATOM   7195  C  CG2  . ILE E 1 143 ? 78.574  -68.120 38.820  1.00 48.64  ? 350 ILE E CG2  1 
ATOM   7196  C  CD1  . ILE E 1 143 ? 76.867  -69.802 40.423  1.00 52.08  ? 350 ILE E CD1  1 
ATOM   7197  N  N    . GLN E 1 144 ? 78.900  -64.788 38.166  1.00 44.40  ? 351 GLN E N    1 
ATOM   7198  C  CA   . GLN E 1 144 ? 79.395  -64.105 36.976  1.00 53.50  ? 351 GLN E CA   1 
ATOM   7199  C  C    . GLN E 1 144 ? 80.111  -65.126 36.085  1.00 59.13  ? 351 GLN E C    1 
ATOM   7200  O  O    . GLN E 1 144 ? 81.178  -65.636 36.464  1.00 53.25  ? 351 GLN E O    1 
ATOM   7201  C  CB   . GLN E 1 144 ? 80.354  -62.984 37.377  1.00 51.94  ? 351 GLN E CB   1 
ATOM   7202  C  CG   . GLN E 1 144 ? 79.722  -61.739 37.961  1.00 48.44  ? 351 GLN E CG   1 
ATOM   7203  C  CD   . GLN E 1 144 ? 79.241  -61.943 39.374  1.00 51.70  ? 351 GLN E CD   1 
ATOM   7204  O  OE1  . GLN E 1 144 ? 79.975  -62.438 40.242  1.00 50.36  ? 351 GLN E OE1  1 
ATOM   7205  N  NE2  . GLN E 1 144 ? 77.990  -61.567 39.620  1.00 49.08  ? 351 GLN E NE2  1 
ATOM   7206  N  N    . LEU E 1 145 ? 79.561  -65.398 34.887  1.00 54.52  ? 352 LEU E N    1 
ATOM   7207  C  CA   . LEU E 1 145 ? 80.172  -66.345 33.950  1.00 52.76  ? 352 LEU E CA   1 
ATOM   7208  C  C    . LEU E 1 145 ? 80.887  -65.597 32.826  1.00 55.18  ? 352 LEU E C    1 
ATOM   7209  O  O    . LEU E 1 145 ? 80.326  -64.662 32.242  1.00 53.46  ? 352 LEU E O    1 
ATOM   7210  C  CB   . LEU E 1 145 ? 79.122  -67.308 33.384  1.00 49.04  ? 352 LEU E CB   1 
ATOM   7211  C  CG   . LEU E 1 145 ? 78.628  -68.348 34.427  1.00 57.56  ? 352 LEU E CG   1 
ATOM   7212  C  CD1  . LEU E 1 145 ? 77.313  -69.021 34.055  1.00 55.05  ? 352 LEU E CD1  1 
ATOM   7213  C  CD2  . LEU E 1 145 ? 79.668  -69.430 34.768  1.00 51.18  ? 352 LEU E CD2  1 
ATOM   7214  N  N    . SER E 1 146 ? 82.127  -66.001 32.527  1.00 54.36  ? 353 SER E N    1 
ATOM   7215  C  CA   . SER E 1 146 ? 82.885  -65.374 31.442  1.00 61.94  ? 353 SER E CA   1 
ATOM   7216  C  C    . SER E 1 146 ? 82.550  -66.024 30.105  1.00 59.20  ? 353 SER E C    1 
ATOM   7217  O  O    . SER E 1 146 ? 82.329  -67.236 30.028  1.00 60.92  ? 353 SER E O    1 
ATOM   7218  C  CB   . SER E 1 146 ? 84.395  -65.438 31.695  1.00 58.22  ? 353 SER E CB   1 
ATOM   7219  O  OG   . SER E 1 146 ? 84.730  -66.623 32.373  1.00 66.48  ? 353 SER E OG   1 
ATOM   7220  N  N    . ILE E 1 147 ? 82.514  -65.202 29.054  1.00 66.81  ? 354 ILE E N    1 
ATOM   7221  C  CA   . ILE E 1 147 ? 81.910  -65.559 27.767  1.00 66.96  ? 354 ILE E CA   1 
ATOM   7222  C  C    . ILE E 1 147 ? 82.965  -65.747 26.679  1.00 65.58  ? 354 ILE E C    1 
ATOM   7223  O  O    . ILE E 1 147 ? 82.976  -66.763 25.987  1.00 65.47  ? 354 ILE E O    1 
ATOM   7224  C  CB   . ILE E 1 147 ? 80.866  -64.501 27.344  1.00 65.36  ? 354 ILE E CB   1 
ATOM   7225  C  CG1  . ILE E 1 147 ? 79.770  -64.370 28.409  1.00 64.06  ? 354 ILE E CG1  1 
ATOM   7226  C  CG2  . ILE E 1 147 ? 80.290  -64.822 25.992  1.00 64.21  ? 354 ILE E CG2  1 
ATOM   7227  C  CD1  . ILE E 1 147 ? 79.115  -65.673 28.777  1.00 63.46  ? 354 ILE E CD1  1 
ATOM   7228  N  N    . LYS E 1 148 ? 83.869  -64.776 26.526  1.00 64.49  ? 355 LYS E N    1 
ATOM   7229  C  CA   . LYS E 1 148 ? 84.876  -64.790 25.466  1.00 65.53  ? 355 LYS E CA   1 
ATOM   7230  C  C    . LYS E 1 148 ? 85.673  -66.091 25.449  1.00 68.98  ? 355 LYS E C    1 
ATOM   7231  O  O    . LYS E 1 148 ? 86.314  -66.459 26.441  1.00 68.09  ? 355 LYS E O    1 
ATOM   7232  N  N    . GLY E 1 149 ? 85.649  -66.768 24.297  1.00 68.80  ? 356 GLY E N    1 
ATOM   7233  C  CA   . GLY E 1 149 ? 86.293  -68.048 24.114  1.00 63.05  ? 356 GLY E CA   1 
ATOM   7234  C  C    . GLY E 1 149 ? 85.485  -69.246 24.572  1.00 72.83  ? 356 GLY E C    1 
ATOM   7235  O  O    . GLY E 1 149 ? 85.991  -70.376 24.507  1.00 74.52  ? 356 GLY E O    1 
ATOM   7236  N  N    . LYS E 1 150 ? 84.257  -69.048 25.043  1.00 67.63  ? 357 LYS E N    1 
ATOM   7237  C  CA   . LYS E 1 150 ? 83.421  -70.140 25.514  1.00 65.80  ? 357 LYS E CA   1 
ATOM   7238  C  C    . LYS E 1 150 ? 82.247  -70.285 24.565  1.00 68.59  ? 357 LYS E C    1 
ATOM   7239  O  O    . LYS E 1 150 ? 81.608  -69.289 24.211  1.00 69.44  ? 357 LYS E O    1 
ATOM   7240  C  CB   . LYS E 1 150 ? 82.921  -69.894 26.943  1.00 64.51  ? 357 LYS E CB   1 
ATOM   7241  C  CG   . LYS E 1 150 ? 83.947  -69.263 27.888  1.00 67.19  ? 357 LYS E CG   1 
ATOM   7242  C  CD   . LYS E 1 150 ? 85.092  -70.199 28.192  1.00 64.69  ? 357 LYS E CD   1 
ATOM   7243  C  CE   . LYS E 1 150 ? 85.961  -69.674 29.336  1.00 66.41  ? 357 LYS E CE   1 
ATOM   7244  N  NZ   . LYS E 1 150 ? 86.352  -68.225 29.236  1.00 65.16  ? 357 LYS E NZ   1 
ATOM   7245  N  N    . LYS E 1 151 ? 81.964  -71.522 24.149  1.00 70.38  ? 358 LYS E N    1 
ATOM   7246  C  CA   . LYS E 1 151 ? 80.825  -71.735 23.267  1.00 69.14  ? 358 LYS E CA   1 
ATOM   7247  C  C    . LYS E 1 151 ? 79.518  -71.798 24.034  1.00 69.75  ? 358 LYS E C    1 
ATOM   7248  O  O    . LYS E 1 151 ? 78.465  -71.437 23.494  1.00 75.09  ? 358 LYS E O    1 
ATOM   7249  C  CB   . LYS E 1 151 ? 81.008  -73.017 22.449  1.00 73.60  ? 358 LYS E CB   1 
ATOM   7250  N  N    . ASN E 1 152 ? 79.591  -72.363 25.237  1.00 67.31  ? 359 ASN E N    1 
ATOM   7251  C  CA   . ASN E 1 152 ? 78.350  -72.632 25.996  1.00 66.58  ? 359 ASN E CA   1 
ATOM   7252  C  C    . ASN E 1 152 ? 78.515  -72.368 27.492  1.00 70.38  ? 359 ASN E C    1 
ATOM   7253  O  O    . ASN E 1 152 ? 79.634  -72.053 27.922  1.00 66.97  ? 359 ASN E O    1 
ATOM   7254  C  CB   . ASN E 1 152 ? 77.924  -74.087 25.806  1.00 64.53  ? 359 ASN E CB   1 
ATOM   7255  C  CG   . ASN E 1 152 ? 79.074  -75.064 25.915  1.00 65.19  ? 359 ASN E CG   1 
ATOM   7256  O  OD1  . ASN E 1 152 ? 79.561  -75.337 27.005  1.00 70.31  ? 359 ASN E OD1  1 
ATOM   7257  N  ND2  . ASN E 1 152 ? 79.513  -75.600 24.790  1.00 71.88  ? 359 ASN E ND2  1 
ATOM   7258  N  N    . ILE E 1 153 ? 77.442  -72.572 28.258  1.00 68.03  ? 360 ILE E N    1 
ATOM   7259  C  CA   . ILE E 1 153 ? 77.451  -72.304 29.726  1.00 62.24  ? 360 ILE E CA   1 
ATOM   7260  C  C    . ILE E 1 153 ? 78.195  -73.408 30.488  1.00 66.04  ? 360 ILE E C    1 
ATOM   7261  O  O    . ILE E 1 153 ? 78.624  -73.128 31.613  1.00 60.92  ? 360 ILE E O    1 
ATOM   7262  C  CB   . ILE E 1 153 ? 76.004  -72.112 30.213  1.00 56.64  ? 360 ILE E CB   1 
ATOM   7263  C  CG1  . ILE E 1 153 ? 75.879  -70.963 31.212  1.00 68.70  ? 360 ILE E CG1  1 
ATOM   7264  C  CG2  . ILE E 1 153 ? 75.434  -73.393 30.777  1.00 63.00  ? 360 ILE E CG2  1 
ATOM   7265  C  CD1  . ILE E 1 153 ? 74.512  -70.867 31.828  1.00 68.73  ? 360 ILE E CD1  1 
ATOM   7266  N  N    . PHE E 1 154 ? 78.377  -74.595 29.901  1.00 63.86  ? 361 PHE E N    1 
ATOM   7267  C  CA   . PHE E 1 154 ? 79.172  -75.643 30.585  1.00 56.37  ? 361 PHE E CA   1 
ATOM   7268  C  C    . PHE E 1 154 ? 80.637  -75.235 30.560  1.00 60.81  ? 361 PHE E C    1 
ATOM   7269  O  O    . PHE E 1 154 ? 81.231  -75.191 31.628  1.00 58.47  ? 361 PHE E O    1 
ATOM   7270  C  CB   . PHE E 1 154 ? 78.962  -77.012 29.947  1.00 60.28  ? 361 PHE E CB   1 
ATOM   7271  C  CG   . PHE E 1 154 ? 79.044  -78.148 30.929  1.00 61.43  ? 361 PHE E CG   1 
ATOM   7272  C  CD1  . PHE E 1 154 ? 77.958  -78.477 31.722  1.00 62.51  ? 361 PHE E CD1  1 
ATOM   7273  C  CD2  . PHE E 1 154 ? 80.213  -78.875 31.074  1.00 57.71  ? 361 PHE E CD2  1 
ATOM   7274  C  CE1  . PHE E 1 154 ? 78.034  -79.520 32.630  1.00 64.85  ? 361 PHE E CE1  1 
ATOM   7275  C  CE2  . PHE E 1 154 ? 80.290  -79.915 31.985  1.00 65.45  ? 361 PHE E CE2  1 
ATOM   7276  C  CZ   . PHE E 1 154 ? 79.200  -80.236 32.759  1.00 69.01  ? 361 PHE E CZ   1 
ATOM   7277  N  N    . GLU E 1 155 ? 81.190  -74.991 29.377  1.00 63.41  ? 362 GLU E N    1 
ATOM   7278  C  CA   . GLU E 1 155 ? 82.560  -74.501 29.241  1.00 63.56  ? 362 GLU E CA   1 
ATOM   7279  C  C    . GLU E 1 155 ? 82.872  -73.384 30.229  1.00 62.05  ? 362 GLU E C    1 
ATOM   7280  O  O    . GLU E 1 155 ? 83.973  -73.319 30.785  1.00 56.74  ? 362 GLU E O    1 
ATOM   7281  C  CB   . GLU E 1 155 ? 82.774  -73.971 27.828  1.00 66.26  ? 362 GLU E CB   1 
ATOM   7282  C  CG   . GLU E 1 155 ? 83.358  -74.947 26.856  1.00 66.97  ? 362 GLU E CG   1 
ATOM   7283  C  CD   . GLU E 1 155 ? 83.806  -74.232 25.620  1.00 70.29  ? 362 GLU E CD   1 
ATOM   7284  O  OE1  . GLU E 1 155 ? 83.098  -74.349 24.601  1.00 78.03  ? 362 GLU E OE1  1 
ATOM   7285  O  OE2  . GLU E 1 155 ? 84.843  -73.523 25.678  1.00 71.49  ? 362 GLU E OE2  1 
ATOM   7286  N  N    . SER E 1 156 ? 81.900  -72.481 30.405  1.00 60.43  ? 363 SER E N    1 
ATOM   7287  C  CA   . SER E 1 156 ? 82.016  -71.389 31.364  1.00 57.61  ? 363 SER E CA   1 
ATOM   7288  C  C    . SER E 1 156 ? 82.197  -71.917 32.789  1.00 60.98  ? 363 SER E C    1 
ATOM   7289  O  O    . SER E 1 156 ? 83.128  -71.518 33.505  1.00 57.54  ? 363 SER E O    1 
ATOM   7290  C  CB   . SER E 1 156 ? 80.770  -70.514 31.257  1.00 57.45  ? 363 SER E CB   1 
ATOM   7291  O  OG   . SER E 1 156 ? 81.032  -69.205 31.688  1.00 59.85  ? 363 SER E OG   1 
ATOM   7292  N  N    . PHE E 1 157 ? 81.324  -72.831 33.205  1.00 58.48  ? 364 PHE E N    1 
ATOM   7293  C  CA   . PHE E 1 157 ? 81.423  -73.434 34.558  1.00 58.54  ? 364 PHE E CA   1 
ATOM   7294  C  C    . PHE E 1 157 ? 82.709  -74.260 34.675  1.00 58.53  ? 364 PHE E C    1 
ATOM   7295  O  O    . PHE E 1 157 ? 83.311  -74.228 35.746  1.00 56.25  ? 364 PHE E O    1 
ATOM   7296  C  CB   . PHE E 1 157 ? 80.165  -74.249 34.850  1.00 56.28  ? 364 PHE E CB   1 
ATOM   7297  C  CG   . PHE E 1 157 ? 79.055  -73.513 35.550  1.00 58.34  ? 364 PHE E CG   1 
ATOM   7298  C  CD1  . PHE E 1 157 ? 79.120  -73.260 36.908  1.00 54.33  ? 364 PHE E CD1  1 
ATOM   7299  C  CD2  . PHE E 1 157 ? 77.934  -73.096 34.854  1.00 56.45  ? 364 PHE E CD2  1 
ATOM   7300  C  CE1  . PHE E 1 157 ? 78.092  -72.593 37.552  1.00 53.22  ? 364 PHE E CE1  1 
ATOM   7301  C  CE2  . PHE E 1 157 ? 76.905  -72.434 35.500  1.00 56.95  ? 364 PHE E CE2  1 
ATOM   7302  C  CZ   . PHE E 1 157 ? 76.988  -72.182 36.847  1.00 52.09  ? 364 PHE E CZ   1 
ATOM   7303  N  N    . VAL E 1 158 ? 83.106  -74.987 33.627  1.00 56.38  ? 365 VAL E N    1 
ATOM   7304  C  CA   . VAL E 1 158 ? 84.390  -75.688 33.662  1.00 54.50  ? 365 VAL E CA   1 
ATOM   7305  C  C    . VAL E 1 158 ? 85.534  -74.704 33.899  1.00 54.24  ? 365 VAL E C    1 
ATOM   7306  O  O    . VAL E 1 158 ? 86.439  -74.962 34.701  1.00 58.68  ? 365 VAL E O    1 
ATOM   7307  C  CB   . VAL E 1 158 ? 84.609  -76.487 32.364  1.00 51.11  ? 365 VAL E CB   1 
ATOM   7308  C  CG1  . VAL E 1 158 ? 86.003  -77.123 32.354  1.00 43.17  ? 365 VAL E CG1  1 
ATOM   7309  C  CG2  . VAL E 1 158 ? 83.529  -77.531 32.193  1.00 57.77  ? 365 VAL E CG2  1 
ATOM   7310  N  N    . ASP E 1 159 ? 85.518  -73.566 33.207  1.00 55.71  ? 366 ASP E N    1 
ATOM   7311  C  CA   . ASP E 1 159 ? 86.624  -72.619 33.341  1.00 61.71  ? 366 ASP E CA   1 
ATOM   7312  C  C    . ASP E 1 159 ? 86.559  -71.854 34.660  1.00 60.03  ? 366 ASP E C    1 
ATOM   7313  O  O    . ASP E 1 159 ? 87.599  -71.556 35.254  1.00 58.86  ? 366 ASP E O    1 
ATOM   7314  C  CB   . ASP E 1 159 ? 86.634  -71.648 32.163  1.00 60.19  ? 366 ASP E CB   1 
ATOM   7315  C  CG   . ASP E 1 159 ? 87.657  -70.552 32.330  1.00 71.53  ? 366 ASP E CG   1 
ATOM   7316  O  OD1  . ASP E 1 159 ? 88.821  -70.884 32.656  1.00 75.47  ? 366 ASP E OD1  1 
ATOM   7317  O  OD2  . ASP E 1 159 ? 87.302  -69.361 32.147  1.00 73.38  ? 366 ASP E OD2  1 
ATOM   7318  N  N    . TYR E 1 160 ? 85.348  -71.533 35.120  1.00 58.61  ? 367 TYR E N    1 
ATOM   7319  C  CA   . TYR E 1 160 ? 85.153  -70.967 36.452  1.00 53.58  ? 367 TYR E CA   1 
ATOM   7320  C  C    . TYR E 1 160 ? 85.849  -71.796 37.532  1.00 55.35  ? 367 TYR E C    1 
ATOM   7321  O  O    . TYR E 1 160 ? 86.490  -71.249 38.437  1.00 54.92  ? 367 TYR E O    1 
ATOM   7322  C  CB   . TYR E 1 160 ? 83.647  -70.858 36.735  1.00 53.91  ? 367 TYR E CB   1 
ATOM   7323  C  CG   . TYR E 1 160 ? 83.299  -69.989 37.913  1.00 53.52  ? 367 TYR E CG   1 
ATOM   7324  C  CD1  . TYR E 1 160 ? 83.580  -70.406 39.211  1.00 55.05  ? 367 TYR E CD1  1 
ATOM   7325  C  CD2  . TYR E 1 160 ? 82.688  -68.744 37.742  1.00 44.49  ? 367 TYR E CD2  1 
ATOM   7326  C  CE1  . TYR E 1 160 ? 83.268  -69.607 40.312  1.00 53.86  ? 367 TYR E CE1  1 
ATOM   7327  C  CE2  . TYR E 1 160 ? 82.373  -67.941 38.849  1.00 51.63  ? 367 TYR E CE2  1 
ATOM   7328  C  CZ   . TYR E 1 160 ? 82.666  -68.385 40.127  1.00 48.11  ? 367 TYR E CZ   1 
ATOM   7329  O  OH   . TYR E 1 160 ? 82.377  -67.619 41.232  1.00 53.89  ? 367 TYR E OH   1 
ATOM   7330  N  N    . VAL E 1 161 ? 85.732  -73.119 37.469  1.00 54.52  ? 368 VAL E N    1 
ATOM   7331  C  CA   . VAL E 1 161 ? 86.330  -73.927 38.529  1.00 55.09  ? 368 VAL E CA   1 
ATOM   7332  C  C    . VAL E 1 161 ? 87.754  -74.350 38.185  1.00 51.90  ? 368 VAL E C    1 
ATOM   7333  O  O    . VAL E 1 161 ? 88.380  -75.096 38.940  1.00 54.91  ? 368 VAL E O    1 
ATOM   7334  C  CB   . VAL E 1 161 ? 85.457  -75.153 38.857  1.00 58.48  ? 368 VAL E CB   1 
ATOM   7335  C  CG1  . VAL E 1 161 ? 84.009  -74.709 39.053  1.00 61.06  ? 368 VAL E CG1  1 
ATOM   7336  C  CG2  . VAL E 1 161 ? 85.563  -76.208 37.770  1.00 56.32  ? 368 VAL E CG2  1 
ATOM   7337  N  N    . ALA E 1 162 ? 88.301  -73.838 37.089  1.00 47.81  ? 369 ALA E N    1 
ATOM   7338  C  CA   . ALA E 1 162 ? 89.635  -74.248 36.671  1.00 54.20  ? 369 ALA E CA   1 
ATOM   7339  C  C    . ALA E 1 162 ? 90.721  -73.638 37.550  1.00 52.87  ? 369 ALA E C    1 
ATOM   7340  O  O    . ALA E 1 162 ? 90.636  -72.484 37.971  1.00 58.01  ? 369 ALA E O    1 
ATOM   7341  C  CB   . ALA E 1 162 ? 89.886  -73.862 35.209  1.00 55.72  ? 369 ALA E CB   1 
ATOM   7342  N  N    . VAL E 1 163 ? 91.770  -74.418 37.794  1.00 52.72  ? 370 VAL E N    1 
ATOM   7343  C  CA   . VAL E 1 163 ? 92.906  -73.947 38.569  1.00 51.97  ? 370 VAL E CA   1 
ATOM   7344  C  C    . VAL E 1 163 ? 93.653  -72.863 37.806  1.00 55.74  ? 370 VAL E C    1 
ATOM   7345  O  O    . VAL E 1 163 ? 94.057  -73.059 36.656  1.00 61.37  ? 370 VAL E O    1 
ATOM   7346  C  CB   . VAL E 1 163 ? 93.844  -75.111 38.887  1.00 48.78  ? 370 VAL E CB   1 
ATOM   7347  C  CG1  . VAL E 1 163 ? 94.996  -74.599 39.774  1.00 52.78  ? 370 VAL E CG1  1 
ATOM   7348  C  CG2  . VAL E 1 163 ? 93.051  -76.261 39.500  1.00 46.39  ? 370 VAL E CG2  1 
ATOM   7349  N  N    . GLU E 1 164 ? 93.882  -71.751 38.489  1.00 57.22  ? 371 GLU E N    1 
ATOM   7350  C  CA   . GLU E 1 164 ? 94.654  -70.651 37.888  1.00 51.67  ? 371 GLU E CA   1 
ATOM   7351  C  C    . GLU E 1 164 ? 96.019  -70.572 38.554  1.00 56.06  ? 371 GLU E C    1 
ATOM   7352  O  O    . GLU E 1 164 ? 96.172  -71.098 39.661  1.00 58.76  ? 371 GLU E O    1 
ATOM   7353  C  CB   . GLU E 1 164 ? 93.965  -69.319 38.147  1.00 51.12  ? 371 GLU E CB   1 
ATOM   7354  C  CG   . GLU E 1 164 ? 92.453  -69.357 38.081  1.00 60.80  ? 371 GLU E CG   1 
ATOM   7355  C  CD   . GLU E 1 164 ? 91.815  -67.983 38.183  1.00 65.47  ? 371 GLU E CD   1 
ATOM   7356  O  OE1  . GLU E 1 164 ? 92.552  -66.985 38.093  1.00 59.39  ? 371 GLU E OE1  1 
ATOM   7357  O  OE2  . GLU E 1 164 ? 90.586  -67.917 38.351  1.00 67.86  ? 371 GLU E OE2  1 
ATOM   7358  N  N    . GLN E 1 165 ? 96.972  -69.930 37.897  1.00 55.00  ? 372 GLN E N    1 
ATOM   7359  C  CA   . GLN E 1 165 ? 98.280  -69.695 38.492  1.00 60.62  ? 372 GLN E CA   1 
ATOM   7360  C  C    . GLN E 1 165 ? 98.308  -68.300 39.113  1.00 59.46  ? 372 GLN E C    1 
ATOM   7361  O  O    . GLN E 1 165 ? 97.842  -67.341 38.497  1.00 61.33  ? 372 GLN E O    1 
ATOM   7362  C  CB   . GLN E 1 165 ? 99.382  -69.846 37.443  1.00 57.54  ? 372 GLN E CB   1 
ATOM   7363  C  CG   . GLN E 1 165 ? 99.490  -71.241 36.904  1.00 52.73  ? 372 GLN E CG   1 
ATOM   7364  C  CD   . GLN E 1 165 ? 99.795  -72.236 37.993  1.00 63.14  ? 372 GLN E CD   1 
ATOM   7365  O  OE1  . GLN E 1 165 ? 100.708 -72.027 38.803  1.00 62.78  ? 372 GLN E OE1  1 
ATOM   7366  N  NE2  . GLN E 1 165 ? 99.024  -73.326 38.037  1.00 61.38  ? 372 GLN E NE2  1 
ATOM   7367  N  N    . LEU E 1 166 ? 98.831  -68.205 40.327  1.00 54.39  ? 373 LEU E N    1 
ATOM   7368  C  CA   . LEU E 1 166 ? 99.007  -66.885 40.963  1.00 54.08  ? 373 LEU E CA   1 
ATOM   7369  C  C    . LEU E 1 166 ? 100.501 -66.576 40.911  1.00 58.39  ? 373 LEU E C    1 
ATOM   7370  O  O    . LEU E 1 166 ? 101.224 -67.029 41.802  1.00 57.03  ? 373 LEU E O    1 
ATOM   7371  C  CB   . LEU E 1 166 ? 98.472  -66.954 42.393  1.00 56.94  ? 373 LEU E CB   1 
ATOM   7372  C  CG   . LEU E 1 166 ? 96.956  -66.857 42.536  1.00 57.71  ? 373 LEU E CG   1 
ATOM   7373  C  CD1  . LEU E 1 166 ? 96.551  -66.899 43.999  1.00 49.08  ? 373 LEU E CD1  1 
ATOM   7374  C  CD2  . LEU E 1 166 ? 96.435  -65.591 41.879  1.00 50.85  ? 373 LEU E CD2  1 
ATOM   7375  N  N    . ASP E 1 167 ? 100.935 -65.837 39.892  1.00 62.09  ? 374 ASP E N    1 
ATOM   7376  C  CA   . ASP E 1 167 ? 102.386 -65.586 39.699  1.00 61.34  ? 374 ASP E CA   1 
ATOM   7377  C  C    . ASP E 1 167 ? 102.652 -64.158 39.221  1.00 58.64  ? 374 ASP E C    1 
ATOM   7378  O  O    . ASP E 1 167 ? 101.696 -63.472 38.848  1.00 57.31  ? 374 ASP E O    1 
ATOM   7379  C  CB   . ASP E 1 167 ? 103.010 -66.620 38.748  1.00 59.31  ? 374 ASP E CB   1 
ATOM   7380  C  CG   . ASP E 1 167 ? 102.324 -66.810 37.407  1.00 64.71  ? 374 ASP E CG   1 
ATOM   7381  O  OD1  . ASP E 1 167 ? 102.678 -67.778 36.717  1.00 66.30  ? 374 ASP E OD1  1 
ATOM   7382  O  OD2  . ASP E 1 167 ? 101.456 -65.997 37.055  1.00 77.59  ? 374 ASP E OD2  1 
ATOM   7383  N  N    . GLY E 1 168 ? 103.915 -63.748 39.241  1.00 52.99  ? 375 GLY E N    1 
ATOM   7384  C  CA   . GLY E 1 168 ? 104.307 -62.420 38.737  1.00 60.99  ? 375 GLY E CA   1 
ATOM   7385  C  C    . GLY E 1 168 ? 103.826 -61.282 39.598  1.00 55.56  ? 375 GLY E C    1 
ATOM   7386  O  O    . GLY E 1 168 ? 104.178 -61.252 40.780  1.00 57.31  ? 375 GLY E O    1 
ATOM   7387  N  N    . ASP E 1 169 ? 103.094 -60.347 38.997  1.00 54.78  ? 376 ASP E N    1 
ATOM   7388  C  CA   . ASP E 1 169 ? 102.513 -59.217 39.760  1.00 55.55  ? 376 ASP E CA   1 
ATOM   7389  C  C    . ASP E 1 169 ? 101.359 -59.755 40.599  1.00 51.67  ? 376 ASP E C    1 
ATOM   7390  O  O    . ASP E 1 169 ? 100.682 -58.950 41.235  1.00 56.42  ? 376 ASP E O    1 
ATOM   7391  C  CB   . ASP E 1 169 ? 102.060 -58.102 38.814  1.00 55.93  ? 376 ASP E CB   1 
ATOM   7392  C  CG   . ASP E 1 169 ? 102.052 -56.715 39.419  1.00 58.83  ? 376 ASP E CG   1 
ATOM   7393  O  OD1  . ASP E 1 169 ? 102.840 -56.478 40.346  1.00 54.43  ? 376 ASP E OD1  1 
ATOM   7394  O  OD2  . ASP E 1 169 ? 101.255 -55.888 38.950  1.00 55.10  ? 376 ASP E OD2  1 
ATOM   7395  N  N    . ASN E 1 170 ? 101.175 -61.074 40.624  1.00 45.56  ? 377 ASN E N    1 
ATOM   7396  C  CA   . ASN E 1 170 ? 100.006 -61.579 41.319  1.00 51.05  ? 377 ASN E CA   1 
ATOM   7397  C  C    . ASN E 1 170 ? 100.376 -62.776 42.171  1.00 55.04  ? 377 ASN E C    1 
ATOM   7398  O  O    . ASN E 1 170 ? 99.563  -63.693 42.355  1.00 55.80  ? 377 ASN E O    1 
ATOM   7399  C  CB   . ASN E 1 170 ? 98.907  -61.943 40.337  1.00 47.47  ? 377 ASN E CB   1 
ATOM   7400  C  CG   . ASN E 1 170 ? 98.392  -60.734 39.597  1.00 53.76  ? 377 ASN E CG   1 
ATOM   7401  O  OD1  . ASN E 1 170 ? 97.591  -59.968 40.140  1.00 57.23  ? 377 ASN E OD1  1 
ATOM   7402  N  ND2  . ASN E 1 170 ? 98.843  -60.545 38.353  1.00 46.78  ? 377 ASN E ND2  1 
ATOM   7403  N  N    . LYS E 1 171 ? 101.617 -62.788 42.658  1.00 50.94  ? 378 LYS E N    1 
ATOM   7404  C  CA   . LYS E 1 171 ? 102.040 -63.703 43.709  1.00 54.42  ? 378 LYS E CA   1 
ATOM   7405  C  C    . LYS E 1 171 ? 101.146 -63.592 44.955  1.00 51.38  ? 378 LYS E C    1 
ATOM   7406  O  O    . LYS E 1 171 ? 100.648 -62.517 45.300  1.00 53.94  ? 378 LYS E O    1 
ATOM   7407  C  CB   . LYS E 1 171 ? 103.497 -63.394 44.074  1.00 52.54  ? 378 LYS E CB   1 
ATOM   7408  C  CG   . LYS E 1 171 ? 104.509 -63.773 43.025  1.00 52.97  ? 378 LYS E CG   1 
ATOM   7409  N  N    . TYR E 1 172 ? 100.987 -64.704 45.673  1.00 52.99  ? 379 TYR E N    1 
ATOM   7410  C  CA   . TYR E 1 172 ? 100.115 -64.757 46.846  1.00 50.95  ? 379 TYR E CA   1 
ATOM   7411  C  C    . TYR E 1 172 ? 100.900 -64.537 48.139  1.00 51.15  ? 379 TYR E C    1 
ATOM   7412  O  O    . TYR E 1 172 ? 101.989 -65.092 48.313  1.00 51.45  ? 379 TYR E O    1 
ATOM   7413  C  CB   . TYR E 1 172 ? 99.397  -66.101 46.858  1.00 46.16  ? 379 TYR E CB   1 
ATOM   7414  C  CG   . TYR E 1 172 ? 98.833  -66.554 48.178  1.00 58.07  ? 379 TYR E CG   1 
ATOM   7415  C  CD1  . TYR E 1 172 ? 97.664  -65.981 48.697  1.00 54.73  ? 379 TYR E CD1  1 
ATOM   7416  C  CD2  . TYR E 1 172 ? 99.448  -67.585 48.904  1.00 52.49  ? 379 TYR E CD2  1 
ATOM   7417  C  CE1  . TYR E 1 172 ? 97.136  -66.413 49.905  1.00 53.68  ? 379 TYR E CE1  1 
ATOM   7418  C  CE2  . TYR E 1 172 ? 98.925  -68.023 50.123  1.00 52.50  ? 379 TYR E CE2  1 
ATOM   7419  C  CZ   . TYR E 1 172 ? 97.770  -67.444 50.608  1.00 54.71  ? 379 TYR E CZ   1 
ATOM   7420  O  OH   . TYR E 1 172 ? 97.246  -67.886 51.796  1.00 55.38  ? 379 TYR E OH   1 
ATOM   7421  N  N    . ASP E 1 173 ? 100.334 -63.726 49.050  1.00 53.65  ? 380 ASP E N    1 
ATOM   7422  C  CA   . ASP E 1 173 ? 100.978 -63.342 50.324  1.00 56.13  ? 380 ASP E CA   1 
ATOM   7423  C  C    . ASP E 1 173 ? 100.831 -64.473 51.343  1.00 55.53  ? 380 ASP E C    1 
ATOM   7424  O  O    . ASP E 1 173 ? 99.803  -64.596 52.018  1.00 53.63  ? 380 ASP E O    1 
ATOM   7425  C  CB   . ASP E 1 173 ? 100.386 -62.035 50.860  1.00 52.70  ? 380 ASP E CB   1 
ATOM   7426  C  CG   . ASP E 1 173 ? 100.894 -61.653 52.293  1.00 55.44  ? 380 ASP E CG   1 
ATOM   7427  O  OD1  . ASP E 1 173 ? 101.826 -62.261 52.851  1.00 57.88  ? 380 ASP E OD1  1 
ATOM   7428  O  OD2  . ASP E 1 173 ? 100.338 -60.712 52.886  1.00 57.02  ? 380 ASP E OD2  1 
ATOM   7429  N  N    . ALA E 1 174 ? 101.883 -65.270 51.498  1.00 53.55  ? 381 ALA E N    1 
ATOM   7430  C  CA   . ALA E 1 174 ? 101.857 -66.462 52.351  1.00 55.39  ? 381 ALA E CA   1 
ATOM   7431  C  C    . ALA E 1 174 ? 102.508 -66.214 53.710  1.00 60.08  ? 381 ALA E C    1 
ATOM   7432  O  O    . ALA E 1 174 ? 103.356 -66.982 54.156  1.00 59.56  ? 381 ALA E O    1 
ATOM   7433  C  CB   . ALA E 1 174 ? 102.530 -67.626 51.632  1.00 55.61  ? 381 ALA E CB   1 
ATOM   7434  N  N    . GLY E 1 175 ? 102.125 -65.132 54.386  1.00 62.41  ? 382 GLY E N    1 
ATOM   7435  C  CA   . GLY E 1 175 ? 102.606 -64.856 55.727  1.00 61.67  ? 382 GLY E CA   1 
ATOM   7436  C  C    . GLY E 1 175 ? 104.117 -64.856 55.894  1.00 68.94  ? 382 GLY E C    1 
ATOM   7437  O  O    . GLY E 1 175 ? 104.841 -64.136 55.187  1.00 66.20  ? 382 GLY E O    1 
ATOM   7438  N  N    . GLU E 1 176 ? 104.597 -65.678 56.835  1.00 66.02  ? 383 GLU E N    1 
ATOM   7439  C  CA   . GLU E 1 176 ? 106.027 -65.754 57.110  1.00 62.24  ? 383 GLU E CA   1 
ATOM   7440  C  C    . GLU E 1 176 ? 106.842 -65.996 55.845  1.00 63.46  ? 383 GLU E C    1 
ATOM   7441  O  O    . GLU E 1 176 ? 108.006 -65.586 55.773  1.00 64.32  ? 383 GLU E O    1 
ATOM   7442  C  CB   . GLU E 1 176 ? 106.303 -66.854 58.137  1.00 65.26  ? 383 GLU E CB   1 
ATOM   7443  N  N    . HIS E 1 177 ? 106.253 -66.637 54.830  1.00 60.40  ? 384 HIS E N    1 
ATOM   7444  C  CA   . HIS E 1 177 ? 106.987 -66.940 53.604  1.00 62.65  ? 384 HIS E CA   1 
ATOM   7445  C  C    . HIS E 1 177 ? 107.016 -65.783 52.619  1.00 67.15  ? 384 HIS E C    1 
ATOM   7446  O  O    . HIS E 1 177 ? 107.587 -65.941 51.529  1.00 62.59  ? 384 HIS E O    1 
ATOM   7447  C  CB   . HIS E 1 177 ? 106.390 -68.161 52.910  1.00 61.54  ? 384 HIS E CB   1 
ATOM   7448  C  CG   . HIS E 1 177 ? 106.357 -69.379 53.774  1.00 68.08  ? 384 HIS E CG   1 
ATOM   7449  N  ND1  . HIS E 1 177 ? 107.341 -70.343 53.740  1.00 72.04  ? 384 HIS E ND1  1 
ATOM   7450  C  CD2  . HIS E 1 177 ? 105.463 -69.787 54.707  1.00 68.44  ? 384 HIS E CD2  1 
ATOM   7451  C  CE1  . HIS E 1 177 ? 107.047 -71.302 54.602  1.00 65.29  ? 384 HIS E CE1  1 
ATOM   7452  N  NE2  . HIS E 1 177 ? 105.914 -70.987 55.203  1.00 70.95  ? 384 HIS E NE2  1 
ATOM   7453  N  N    . GLY E 1 178 ? 106.423 -64.636 52.974  1.00 63.23  ? 385 GLY E N    1 
ATOM   7454  C  CA   . GLY E 1 178 ? 106.333 -63.531 52.064  1.00 54.83  ? 385 GLY E CA   1 
ATOM   7455  C  C    . GLY E 1 178 ? 105.480 -63.909 50.859  1.00 61.72  ? 385 GLY E C    1 
ATOM   7456  O  O    . GLY E 1 178 ? 104.610 -64.790 50.908  1.00 61.44  ? 385 GLY E O    1 
ATOM   7457  N  N    . LEU E 1 179 ? 105.734 -63.214 49.760  1.00 51.85  ? 386 LEU E N    1 
ATOM   7458  C  CA   . LEU E 1 179 ? 104.971 -63.471 48.553  1.00 57.45  ? 386 LEU E CA   1 
ATOM   7459  C  C    . LEU E 1 179 ? 105.526 -64.692 47.824  1.00 64.63  ? 386 LEU E C    1 
ATOM   7460  O  O    . LEU E 1 179 ? 106.737 -64.949 47.813  1.00 63.67  ? 386 LEU E O    1 
ATOM   7461  C  CB   . LEU E 1 179 ? 104.964 -62.246 47.645  1.00 56.84  ? 386 LEU E CB   1 
ATOM   7462  C  CG   . LEU E 1 179 ? 104.111 -61.106 48.198  1.00 61.34  ? 386 LEU E CG   1 
ATOM   7463  C  CD1  . LEU E 1 179 ? 104.635 -59.777 47.704  1.00 60.99  ? 386 LEU E CD1  1 
ATOM   7464  C  CD2  . LEU E 1 179 ? 102.636 -61.283 47.831  1.00 57.80  ? 386 LEU E CD2  1 
ATOM   7465  N  N    . GLN E 1 180 ? 104.593 -65.529 47.378  1.00 63.85  ? 387 GLN E N    1 
ATOM   7466  C  CA   . GLN E 1 180 ? 104.996 -66.822 46.803  1.00 52.00  ? 387 GLN E CA   1 
ATOM   7467  C  C    . GLN E 1 180 ? 104.131 -67.171 45.605  1.00 54.65  ? 387 GLN E C    1 
ATOM   7468  O  O    . GLN E 1 180 ? 102.955 -66.802 45.597  1.00 60.77  ? 387 GLN E O    1 
ATOM   7469  C  CB   . GLN E 1 180 ? 104.731 -67.899 47.851  1.00 54.34  ? 387 GLN E CB   1 
ATOM   7470  C  CG   . GLN E 1 180 ? 105.687 -67.907 49.029  1.00 56.32  ? 387 GLN E CG   1 
ATOM   7471  C  CD   . GLN E 1 180 ? 107.036 -68.464 48.657  1.00 66.32  ? 387 GLN E CD   1 
ATOM   7472  O  OE1  . GLN E 1 180 ? 107.164 -69.311 47.776  1.00 61.36  ? 387 GLN E OE1  1 
ATOM   7473  N  NE2  . GLN E 1 180 ? 108.060 -67.989 49.341  1.00 66.36  ? 387 GLN E NE2  1 
ATOM   7474  N  N    . GLU E 1 181 ? 104.696 -67.896 44.650  1.00 56.25  ? 388 GLU E N    1 
ATOM   7475  C  CA   . GLU E 1 181 ? 103.898 -68.401 43.512  1.00 55.67  ? 388 GLU E CA   1 
ATOM   7476  C  C    . GLU E 1 181 ? 102.906 -69.425 44.058  1.00 59.30  ? 388 GLU E C    1 
ATOM   7477  O  O    . GLU E 1 181 ? 103.306 -70.233 44.914  1.00 59.63  ? 388 GLU E O    1 
ATOM   7478  C  CB   . GLU E 1 181 ? 104.824 -69.039 42.486  1.00 59.63  ? 388 GLU E CB   1 
ATOM   7479  C  CG   . GLU E 1 181 ? 105.295 -68.100 41.402  1.00 63.47  ? 388 GLU E CG   1 
ATOM   7480  C  CD   . GLU E 1 181 ? 106.248 -68.785 40.443  1.00 68.64  ? 388 GLU E CD   1 
ATOM   7481  O  OE1  . GLU E 1 181 ? 105.775 -69.567 39.600  1.00 71.29  ? 388 GLU E OE1  1 
ATOM   7482  O  OE2  . GLU E 1 181 ? 107.460 -68.548 40.558  1.00 75.04  ? 388 GLU E OE2  1 
ATOM   7483  N  N    . ALA E 1 182 ? 101.672 -69.407 43.563  1.00 56.03  ? 389 ALA E N    1 
ATOM   7484  C  CA   . ALA E 1 182 ? 100.642 -70.287 44.145  1.00 52.85  ? 389 ALA E CA   1 
ATOM   7485  C  C    . ALA E 1 182 ? 99.615  -70.713 43.111  1.00 50.67  ? 389 ALA E C    1 
ATOM   7486  O  O    . ALA E 1 182 ? 99.701  -70.276 41.971  1.00 54.94  ? 389 ALA E O    1 
ATOM   7487  C  CB   . ALA E 1 182 ? 99.957  -69.564 45.266  1.00 49.77  ? 389 ALA E CB   1 
ATOM   7488  N  N    . GLU E 1 183 ? 98.693  -71.574 43.525  1.00 53.88  ? 390 GLU E N    1 
ATOM   7489  C  CA   . GLU E 1 183 ? 97.591  -71.980 42.630  1.00 52.51  ? 390 GLU E CA   1 
ATOM   7490  C  C    . GLU E 1 183 ? 96.280  -71.624 43.325  1.00 50.94  ? 390 GLU E C    1 
ATOM   7491  O  O    . GLU E 1 183 ? 96.238  -71.671 44.551  1.00 52.79  ? 390 GLU E O    1 
ATOM   7492  C  CB   . GLU E 1 183 ? 97.653  -73.480 42.362  1.00 57.77  ? 390 GLU E CB   1 
ATOM   7493  C  CG   . GLU E 1 183 ? 98.835  -73.912 41.522  1.00 64.30  ? 390 GLU E CG   1 
ATOM   7494  C  CD   . GLU E 1 183 ? 98.668  -75.282 40.890  1.00 71.36  ? 390 GLU E CD   1 
ATOM   7495  O  OE1  . GLU E 1 183 ? 97.829  -76.060 41.379  1.00 68.61  ? 390 GLU E OE1  1 
ATOM   7496  O  OE2  . GLU E 1 183 ? 99.375  -75.565 39.907  1.00 69.43  ? 390 GLU E OE2  1 
ATOM   7497  N  N    . LYS E 1 184 ? 95.257  -71.268 42.558  1.00 52.12  ? 391 LYS E N    1 
ATOM   7498  C  CA   . LYS E 1 184 ? 93.930  -70.962 43.144  1.00 50.84  ? 391 LYS E CA   1 
ATOM   7499  C  C    . LYS E 1 184 ? 92.848  -71.742 42.410  1.00 50.75  ? 391 LYS E C    1 
ATOM   7500  O  O    . LYS E 1 184 ? 92.888  -71.793 41.183  1.00 51.26  ? 391 LYS E O    1 
ATOM   7501  C  CB   . LYS E 1 184 ? 93.604  -69.468 43.117  1.00 41.60  ? 391 LYS E CB   1 
ATOM   7502  N  N    . GLY E 1 185 ? 91.928  -72.318 43.167  1.00 47.00  ? 392 GLY E N    1 
ATOM   7503  C  CA   . GLY E 1 185 ? 90.812  -73.065 42.574  1.00 43.14  ? 392 GLY E CA   1 
ATOM   7504  C  C    . GLY E 1 185 ? 89.532  -72.801 43.330  1.00 49.38  ? 392 GLY E C    1 
ATOM   7505  O  O    . GLY E 1 185 ? 89.533  -72.923 44.549  1.00 54.64  ? 392 GLY E O    1 
ATOM   7506  N  N    . VAL E 1 186 ? 88.476  -72.438 42.616  1.00 51.51  ? 393 VAL E N    1 
ATOM   7507  C  CA   . VAL E 1 186 ? 87.195  -72.180 43.238  1.00 52.71  ? 393 VAL E CA   1 
ATOM   7508  C  C    . VAL E 1 186 ? 86.291  -73.375 42.975  1.00 55.38  ? 393 VAL E C    1 
ATOM   7509  O  O    . VAL E 1 186 ? 86.361  -74.001 41.908  1.00 51.31  ? 393 VAL E O    1 
ATOM   7510  C  CB   . VAL E 1 186 ? 86.581  -70.869 42.720  1.00 49.41  ? 393 VAL E CB   1 
ATOM   7511  C  CG1  . VAL E 1 186 ? 85.315  -70.574 43.500  1.00 50.57  ? 393 VAL E CG1  1 
ATOM   7512  C  CG2  . VAL E 1 186 ? 87.594  -69.731 42.879  1.00 44.27  ? 393 VAL E CG2  1 
ATOM   7513  N  N    . LYS E 1 187 ? 85.490  -73.713 43.979  1.00 54.90  ? 394 LYS E N    1 
ATOM   7514  C  CA   . LYS E 1 187 ? 84.472  -74.769 43.817  1.00 54.17  ? 394 LYS E CA   1 
ATOM   7515  C  C    . LYS E 1 187 ? 83.225  -74.315 44.568  1.00 56.52  ? 394 LYS E C    1 
ATOM   7516  O  O    . LYS E 1 187 ? 83.357  -73.509 45.466  1.00 57.77  ? 394 LYS E O    1 
ATOM   7517  C  CB   . LYS E 1 187 ? 84.978  -76.103 44.366  1.00 58.23  ? 394 LYS E CB   1 
ATOM   7518  C  CG   . LYS E 1 187 ? 85.704  -76.996 43.373  1.00 58.64  ? 394 LYS E CG   1 
ATOM   7519  C  CD   . LYS E 1 187 ? 84.893  -78.194 42.952  1.00 67.79  ? 394 LYS E CD   1 
ATOM   7520  C  CE   . LYS E 1 187 ? 84.926  -78.435 41.460  1.00 65.39  ? 394 LYS E CE   1 
ATOM   7521  N  NZ   . LYS E 1 187 ? 86.293  -78.277 40.911  1.00 75.00  ? 394 LYS E NZ   1 
ATOM   7522  N  N    . PHE E 1 188 ? 82.050  -74.773 44.170  1.00 58.40  ? 395 PHE E N    1 
ATOM   7523  C  CA   . PHE E 1 188 ? 80.806  -74.491 44.864  1.00 54.66  ? 395 PHE E CA   1 
ATOM   7524  C  C    . PHE E 1 188 ? 80.593  -75.515 45.961  1.00 52.79  ? 395 PHE E C    1 
ATOM   7525  O  O    . PHE E 1 188 ? 80.767  -76.715 45.731  1.00 57.91  ? 395 PHE E O    1 
ATOM   7526  C  CB   . PHE E 1 188 ? 79.634  -74.505 43.893  1.00 50.35  ? 395 PHE E CB   1 
ATOM   7527  C  CG   . PHE E 1 188 ? 79.726  -73.438 42.859  1.00 57.83  ? 395 PHE E CG   1 
ATOM   7528  C  CD1  . PHE E 1 188 ? 79.506  -72.112 43.200  1.00 58.44  ? 395 PHE E CD1  1 
ATOM   7529  C  CD2  . PHE E 1 188 ? 80.081  -73.743 41.563  1.00 56.76  ? 395 PHE E CD2  1 
ATOM   7530  C  CE1  . PHE E 1 188 ? 79.601  -71.123 42.256  1.00 55.52  ? 395 PHE E CE1  1 
ATOM   7531  C  CE2  . PHE E 1 188 ? 80.173  -72.760 40.616  1.00 57.47  ? 395 PHE E CE2  1 
ATOM   7532  C  CZ   . PHE E 1 188 ? 79.938  -71.448 40.957  1.00 56.58  ? 395 PHE E CZ   1 
ATOM   7533  N  N    . LEU E 1 189 ? 80.151  -75.054 47.125  1.00 49.46  ? 396 LEU E N    1 
ATOM   7534  C  CA   . LEU E 1 189 ? 79.767  -75.995 48.204  1.00 52.80  ? 396 LEU E CA   1 
ATOM   7535  C  C    . LEU E 1 189 ? 78.258  -76.196 48.100  1.00 50.44  ? 396 LEU E C    1 
ATOM   7536  O  O    . LEU E 1 189 ? 77.831  -77.349 48.145  1.00 54.39  ? 396 LEU E O    1 
ATOM   7537  C  CB   . LEU E 1 189 ? 80.183  -75.411 49.554  1.00 48.03  ? 396 LEU E CB   1 
ATOM   7538  C  CG   . LEU E 1 189 ? 81.678  -75.444 49.844  1.00 52.43  ? 396 LEU E CG   1 
ATOM   7539  C  CD1  . LEU E 1 189 ? 81.958  -74.912 51.235  1.00 51.82  ? 396 LEU E CD1  1 
ATOM   7540  C  CD2  . LEU E 1 189 ? 82.221  -76.854 49.698  1.00 46.15  ? 396 LEU E CD2  1 
ATOM   7541  N  N    . THR E 1 190 ? 77.513  -75.105 48.020  1.00 53.28  ? 397 THR E N    1 
ATOM   7542  C  CA   . THR E 1 190 ? 76.043  -75.181 47.877  1.00 52.24  ? 397 THR E CA   1 
ATOM   7543  C  C    . THR E 1 190 ? 75.629  -74.448 46.603  1.00 55.46  ? 397 THR E C    1 
ATOM   7544  O  O    . THR E 1 190 ? 76.350  -73.527 46.201  1.00 53.52  ? 397 THR E O    1 
ATOM   7545  C  CB   . THR E 1 190 ? 75.331  -74.634 49.123  1.00 49.56  ? 397 THR E CB   1 
ATOM   7546  O  OG1  . THR E 1 190 ? 75.635  -73.253 49.295  1.00 50.71  ? 397 THR E OG1  1 
ATOM   7547  C  CG2  . THR E 1 190 ? 75.686  -75.384 50.387  1.00 42.00  ? 397 THR E CG2  1 
ATOM   7548  N  N    . LEU E 1 191 ? 74.548  -74.893 45.966  1.00 52.98  ? 398 LEU E N    1 
ATOM   7549  C  CA   . LEU E 1 191 ? 73.991  -74.163 44.800  1.00 51.51  ? 398 LEU E CA   1 
ATOM   7550  C  C    . LEU E 1 191 ? 72.546  -73.804 45.152  1.00 48.63  ? 398 LEU E C    1 
ATOM   7551  O  O    . LEU E 1 191 ? 71.804  -74.695 45.572  1.00 53.10  ? 398 LEU E O    1 
ATOM   7552  C  CB   . LEU E 1 191 ? 74.130  -75.003 43.528  1.00 54.01  ? 398 LEU E CB   1 
ATOM   7553  C  CG   . LEU E 1 191 ? 75.476  -74.904 42.817  1.00 57.26  ? 398 LEU E CG   1 
ATOM   7554  C  CD1  . LEU E 1 191 ? 75.703  -76.112 41.929  1.00 55.19  ? 398 LEU E CD1  1 
ATOM   7555  C  CD2  . LEU E 1 191 ? 75.560  -73.632 41.998  1.00 51.28  ? 398 LEU E CD2  1 
ATOM   7556  N  N    . PRO E 1 192 ? 72.118  -72.534 44.999  1.00 51.59  ? 399 PRO E N    1 
ATOM   7557  C  CA   . PRO E 1 192 ? 70.795  -72.093 45.469  1.00 58.22  ? 399 PRO E CA   1 
ATOM   7558  C  C    . PRO E 1 192 ? 69.563  -72.637 44.735  1.00 57.48  ? 399 PRO E C    1 
ATOM   7559  O  O    . PRO E 1 192 ? 69.686  -72.976 43.590  1.00 56.48  ? 399 PRO E O    1 
ATOM   7560  C  CB   . PRO E 1 192 ? 70.869  -70.579 45.259  1.00 51.43  ? 399 PRO E CB   1 
ATOM   7561  C  CG   . PRO E 1 192 ? 71.855  -70.386 44.150  1.00 50.58  ? 399 PRO E CG   1 
ATOM   7562  C  CD   . PRO E 1 192 ? 72.885  -71.463 44.379  1.00 54.49  ? 399 PRO E CD   1 
ATOM   7563  N  N    . PRO E 1 193 ? 68.364  -72.699 45.357  1.00 57.38  ? 400 PRO E N    1 
ATOM   7564  C  CA   . PRO E 1 193 ? 67.184  -73.166 44.603  1.00 58.67  ? 400 PRO E CA   1 
ATOM   7565  C  C    . PRO E 1 193 ? 66.916  -72.343 43.368  1.00 59.67  ? 400 PRO E C    1 
ATOM   7566  O  O    . PRO E 1 193 ? 66.434  -72.889 42.368  1.00 59.95  ? 400 PRO E O    1 
ATOM   7567  C  CB   . PRO E 1 193 ? 66.040  -73.044 45.617  1.00 55.49  ? 400 PRO E CB   1 
ATOM   7568  C  CG   . PRO E 1 193 ? 66.724  -73.117 46.952  1.00 61.58  ? 400 PRO E CG   1 
ATOM   7569  C  CD   . PRO E 1 193 ? 68.042  -72.387 46.758  1.00 50.24  ? 400 PRO E CD   1 
ATOM   7570  N  N    . VAL E 1 194 ? 67.222  -71.047 43.403  1.00 58.89  ? 401 VAL E N    1 
ATOM   7571  C  CA   . VAL E 1 194 ? 67.110  -70.167 42.242  1.00 59.30  ? 401 VAL E CA   1 
ATOM   7572  C  C    . VAL E 1 194 ? 68.493  -69.627 41.925  1.00 55.69  ? 401 VAL E C    1 
ATOM   7573  O  O    . VAL E 1 194 ? 69.127  -68.988 42.778  1.00 58.06  ? 401 VAL E O    1 
ATOM   7574  C  CB   . VAL E 1 194 ? 66.116  -69.026 42.478  1.00 60.13  ? 401 VAL E CB   1 
ATOM   7575  C  CG1  . VAL E 1 194 ? 65.938  -68.229 41.188  1.00 58.82  ? 401 VAL E CG1  1 
ATOM   7576  C  CG2  . VAL E 1 194 ? 64.796  -69.599 42.971  1.00 48.82  ? 401 VAL E CG2  1 
ATOM   7577  N  N    . LEU E 1 195 ? 68.962  -69.907 40.714  1.00 53.94  ? 402 LEU E N    1 
ATOM   7578  C  CA   . LEU E 1 195 ? 70.320  -69.612 40.277  1.00 55.84  ? 402 LEU E CA   1 
ATOM   7579  C  C    . LEU E 1 195 ? 70.274  -68.414 39.353  1.00 57.17  ? 402 LEU E C    1 
ATOM   7580  O  O    . LEU E 1 195 ? 69.618  -68.469 38.304  1.00 57.56  ? 402 LEU E O    1 
ATOM   7581  C  CB   . LEU E 1 195 ? 70.929  -70.798 39.539  1.00 56.92  ? 402 LEU E CB   1 
ATOM   7582  C  CG   . LEU E 1 195 ? 72.146  -71.416 40.201  1.00 56.91  ? 402 LEU E CG   1 
ATOM   7583  C  CD1  . LEU E 1 195 ? 72.811  -72.374 39.240  1.00 54.45  ? 402 LEU E CD1  1 
ATOM   7584  C  CD2  . LEU E 1 195 ? 73.086  -70.320 40.591  1.00 56.30  ? 402 LEU E CD2  1 
ATOM   7585  N  N    . HIS E 1 196 ? 70.948  -67.335 39.745  1.00 52.06  ? 403 HIS E N    1 
ATOM   7586  C  CA   . HIS E 1 196 ? 71.052  -66.146 38.910  1.00 47.88  ? 403 HIS E CA   1 
ATOM   7587  C  C    . HIS E 1 196 ? 72.434  -66.150 38.292  1.00 52.17  ? 403 HIS E C    1 
ATOM   7588  O  O    . HIS E 1 196 ? 73.440  -66.211 39.019  1.00 51.15  ? 403 HIS E O    1 
ATOM   7589  C  CB   . HIS E 1 196 ? 70.820  -64.866 39.709  1.00 48.87  ? 403 HIS E CB   1 
ATOM   7590  C  CG   . HIS E 1 196 ? 69.379  -64.602 40.013  1.00 51.95  ? 403 HIS E CG   1 
ATOM   7591  N  ND1  . HIS E 1 196 ? 68.932  -63.405 40.530  1.00 53.41  ? 403 HIS E ND1  1 
ATOM   7592  C  CD2  . HIS E 1 196 ? 68.281  -65.379 39.859  1.00 51.41  ? 403 HIS E CD2  1 
ATOM   7593  C  CE1  . HIS E 1 196 ? 67.621  -63.461 40.690  1.00 47.95  ? 403 HIS E CE1  1 
ATOM   7594  N  NE2  . HIS E 1 196 ? 67.202  -64.645 40.281  1.00 50.30  ? 403 HIS E NE2  1 
ATOM   7595  N  N    . LEU E 1 197 ? 72.457  -66.092 36.967  1.00 43.64  ? 404 LEU E N    1 
ATOM   7596  C  CA   . LEU E 1 197 ? 73.739  -66.127 36.239  1.00 48.46  ? 404 LEU E CA   1 
ATOM   7597  C  C    . LEU E 1 197 ? 73.893  -64.851 35.422  1.00 46.89  ? 404 LEU E C    1 
ATOM   7598  O  O    . LEU E 1 197 ? 72.985  -64.530 34.677  1.00 50.73  ? 404 LEU E O    1 
ATOM   7599  C  CB   . LEU E 1 197 ? 73.766  -67.379 35.361  1.00 49.31  ? 404 LEU E CB   1 
ATOM   7600  C  CG   . LEU E 1 197 ? 73.582  -68.697 36.108  1.00 53.63  ? 404 LEU E CG   1 
ATOM   7601  C  CD1  . LEU E 1 197 ? 73.372  -69.843 35.144  1.00 50.51  ? 404 LEU E CD1  1 
ATOM   7602  C  CD2  . LEU E 1 197 ? 74.769  -68.983 37.002  1.00 41.96  ? 404 LEU E CD2  1 
ATOM   7603  N  N    . GLN E 1 198 ? 75.006  -64.152 35.592  1.00 49.12  ? 405 GLN E N    1 
ATOM   7604  C  CA   . GLN E 1 198 ? 75.313  -62.933 34.866  1.00 49.12  ? 405 GLN E CA   1 
ATOM   7605  C  C    . GLN E 1 198 ? 76.334  -63.300 33.812  1.00 50.01  ? 405 GLN E C    1 
ATOM   7606  O  O    . GLN E 1 198 ? 77.417  -63.801 34.141  1.00 51.73  ? 405 GLN E O    1 
ATOM   7607  C  CB   . GLN E 1 198 ? 75.856  -61.861 35.809  1.00 53.57  ? 405 GLN E CB   1 
ATOM   7608  C  CG   . GLN E 1 198 ? 75.966  -60.466 35.214  1.00 55.75  ? 405 GLN E CG   1 
ATOM   7609  C  CD   . GLN E 1 198 ? 76.810  -59.541 36.083  1.00 58.03  ? 405 GLN E CD   1 
ATOM   7610  O  OE1  . GLN E 1 198 ? 77.098  -59.870 37.238  1.00 52.56  ? 405 GLN E OE1  1 
ATOM   7611  N  NE2  . GLN E 1 198 ? 77.227  -58.385 35.525  1.00 53.95  ? 405 GLN E NE2  1 
ATOM   7612  N  N    . LEU E 1 199 ? 75.973  -63.115 32.553  1.00 51.82  ? 406 LEU E N    1 
ATOM   7613  C  CA   . LEU E 1 199 ? 76.897  -63.395 31.464  1.00 53.94  ? 406 LEU E CA   1 
ATOM   7614  C  C    . LEU E 1 199 ? 77.754  -62.161 31.237  1.00 54.16  ? 406 LEU E C    1 
ATOM   7615  O  O    . LEU E 1 199 ? 77.235  -61.046 31.149  1.00 56.04  ? 406 LEU E O    1 
ATOM   7616  C  CB   . LEU E 1 199 ? 76.140  -63.792 30.198  1.00 61.08  ? 406 LEU E CB   1 
ATOM   7617  C  CG   . LEU E 1 199 ? 75.069  -64.891 30.344  1.00 59.99  ? 406 LEU E CG   1 
ATOM   7618  C  CD1  . LEU E 1 199 ? 74.640  -65.402 28.968  1.00 57.08  ? 406 LEU E CD1  1 
ATOM   7619  C  CD2  . LEU E 1 199 ? 75.511  -66.062 31.261  1.00 47.82  ? 406 LEU E CD2  1 
ATOM   7620  N  N    . MET E 1 200 ? 79.064  -62.356 31.189  1.00 57.95  ? 407 MET E N    1 
ATOM   7621  C  CA   . MET E 1 200 ? 80.009  -61.240 31.165  1.00 55.46  ? 407 MET E CA   1 
ATOM   7622  C  C    . MET E 1 200 ? 80.238  -60.781 29.727  1.00 62.78  ? 407 MET E C    1 
ATOM   7623  O  O    . MET E 1 200 ? 81.301  -60.966 29.118  1.00 60.30  ? 407 MET E O    1 
ATOM   7624  C  CB   . MET E 1 200 ? 81.295  -61.651 31.849  1.00 58.53  ? 407 MET E CB   1 
ATOM   7625  C  CG   . MET E 1 200 ? 81.020  -61.957 33.285  1.00 62.08  ? 407 MET E CG   1 
ATOM   7626  S  SD   . MET E 1 200 ? 81.454  -60.552 34.279  1.00 64.02  ? 407 MET E SD   1 
ATOM   7627  C  CE   . MET E 1 200 ? 83.044  -61.141 34.845  1.00 62.30  ? 407 MET E CE   1 
ATOM   7628  N  N    . ARG E 1 201 ? 79.199  -60.158 29.183  1.00 58.91  ? 408 ARG E N    1 
ATOM   7629  C  CA   . ARG E 1 201 ? 79.253  -59.736 27.769  1.00 61.08  ? 408 ARG E CA   1 
ATOM   7630  C  C    . ARG E 1 201 ? 79.893  -58.359 27.685  1.00 61.78  ? 408 ARG E C    1 
ATOM   7631  O  O    . ARG E 1 201 ? 79.279  -57.466 27.099  1.00 68.93  ? 408 ARG E O    1 
ATOM   7632  C  CB   . ARG E 1 201 ? 77.837  -59.756 27.200  1.00 62.62  ? 408 ARG E CB   1 
ATOM   7633  C  CG   . ARG E 1 201 ? 77.224  -61.143 27.111  1.00 59.64  ? 408 ARG E CG   1 
ATOM   7634  C  CD   . ARG E 1 201 ? 76.116  -61.095 26.085  1.00 65.65  ? 408 ARG E CD   1 
ATOM   7635  N  NE   . ARG E 1 201 ? 75.724  -62.400 25.579  1.00 67.65  ? 408 ARG E NE   1 
ATOM   7636  C  CZ   . ARG E 1 201 ? 76.220  -62.970 24.489  1.00 66.77  ? 408 ARG E CZ   1 
ATOM   7637  N  NH1  . ARG E 1 201 ? 77.139  -62.348 23.773  1.00 65.14  ? 408 ARG E NH1  1 
ATOM   7638  N  NH2  . ARG E 1 201 ? 75.788  -64.159 24.115  1.00 64.92  ? 408 ARG E NH2  1 
ATOM   7639  N  N    . PHE E 1 202 ? 81.079  -58.214 28.261  1.00 59.35  ? 409 PHE E N    1 
ATOM   7640  C  CA   . PHE E 1 202 ? 81.818  -56.935 28.152  1.00 61.89  ? 409 PHE E CA   1 
ATOM   7641  C  C    . PHE E 1 202 ? 83.330  -57.184 28.260  1.00 64.82  ? 409 PHE E C    1 
ATOM   7642  O  O    . PHE E 1 202 ? 83.733  -58.129 28.956  1.00 59.78  ? 409 PHE E O    1 
ATOM   7643  C  CB   . PHE E 1 202 ? 81.309  -55.902 29.164  1.00 61.34  ? 409 PHE E CB   1 
ATOM   7644  C  CG   . PHE E 1 202 ? 80.652  -56.411 30.419  1.00 60.93  ? 409 PHE E CG   1 
ATOM   7645  C  CD1  . PHE E 1 202 ? 81.364  -57.143 31.355  1.00 61.12  ? 409 PHE E CD1  1 
ATOM   7646  C  CD2  . PHE E 1 202 ? 79.328  -56.106 30.684  1.00 58.63  ? 409 PHE E CD2  1 
ATOM   7647  C  CE1  . PHE E 1 202 ? 80.751  -57.589 32.512  1.00 59.15  ? 409 PHE E CE1  1 
ATOM   7648  C  CE2  . PHE E 1 202 ? 78.720  -56.551 31.844  1.00 53.79  ? 409 PHE E CE2  1 
ATOM   7649  C  CZ   . PHE E 1 202 ? 79.431  -57.294 32.754  1.00 58.61  ? 409 PHE E CZ   1 
ATOM   7650  N  N    . MET E 1 203 ? 84.132  -56.372 27.566  1.00 66.39  ? 410 MET E N    1 
ATOM   7651  C  CA   . MET E 1 203 ? 85.615  -56.474 27.636  1.00 69.39  ? 410 MET E CA   1 
ATOM   7652  C  C    . MET E 1 203 ? 86.228  -55.111 27.322  1.00 68.95  ? 410 MET E C    1 
ATOM   7653  O  O    . MET E 1 203 ? 85.633  -54.403 26.508  1.00 73.74  ? 410 MET E O    1 
ATOM   7654  C  CB   . MET E 1 203 ? 86.176  -57.514 26.661  1.00 75.61  ? 410 MET E CB   1 
ATOM   7655  C  CG   . MET E 1 203 ? 86.041  -57.189 25.188  1.00 74.59  ? 410 MET E CG   1 
ATOM   7656  S  SD   . MET E 1 203 ? 86.911  -58.417 24.188  1.00 88.52  ? 410 MET E SD   1 
ATOM   7657  C  CE   . MET E 1 203 ? 85.950  -58.354 22.678  1.00 78.56  ? 410 MET E CE   1 
ATOM   7658  N  N    . GLN E 1 210 ? 86.907  -47.778 24.828  1.00 86.00  ? 417 GLN E N    1 
ATOM   7659  C  CA   . GLN E 1 210 ? 87.985  -48.526 25.464  1.00 93.51  ? 417 GLN E CA   1 
ATOM   7660  C  C    . GLN E 1 210 ? 87.487  -49.923 25.867  1.00 91.78  ? 417 GLN E C    1 
ATOM   7661  O  O    . GLN E 1 210 ? 88.224  -50.908 25.768  1.00 93.70  ? 417 GLN E O    1 
ATOM   7662  C  CB   . GLN E 1 210 ? 88.526  -47.759 26.678  1.00 91.38  ? 417 GLN E CB   1 
ATOM   7663  N  N    . ASN E 1 211 ? 86.224  -50.030 26.234  1.00 87.80  ? 418 ASN E N    1 
ATOM   7664  C  CA   . ASN E 1 211 ? 85.571  -51.279 26.688  1.00 84.69  ? 418 ASN E CA   1 
ATOM   7665  C  C    . ASN E 1 211 ? 84.251  -51.314 25.929  1.00 82.25  ? 418 ASN E C    1 
ATOM   7666  O  O    . ASN E 1 211 ? 83.649  -50.242 25.735  1.00 85.83  ? 418 ASN E O    1 
ATOM   7667  C  CB   . ASN E 1 211 ? 85.480  -51.385 28.215  1.00 81.22  ? 418 ASN E CB   1 
ATOM   7668  N  N    . ILE E 1 212 ? 83.778  -52.493 25.581  1.00 77.59  ? 419 ILE E N    1 
ATOM   7669  C  CA   . ILE E 1 212 ? 82.683  -52.690 24.633  1.00 72.79  ? 419 ILE E CA   1 
ATOM   7670  C  C    . ILE E 1 212 ? 81.840  -53.887 25.060  1.00 70.22  ? 419 ILE E C    1 
ATOM   7671  O  O    . ILE E 1 212 ? 82.251  -54.706 25.883  1.00 68.34  ? 419 ILE E O    1 
ATOM   7672  C  CB   . ILE E 1 212 ? 83.207  -52.933 23.203  1.00 71.78  ? 419 ILE E CB   1 
ATOM   7673  C  CG1  . ILE E 1 212 ? 83.876  -54.303 23.151  1.00 66.41  ? 419 ILE E CG1  1 
ATOM   7674  C  CG2  . ILE E 1 212 ? 84.201  -51.855 22.775  1.00 71.32  ? 419 ILE E CG2  1 
ATOM   7675  C  CD1  . ILE E 1 212 ? 84.508  -54.616 21.839  1.00 75.61  ? 419 ILE E CD1  1 
ATOM   7676  N  N    . LYS E 1 213 ? 80.689  -54.009 24.402  1.00 67.53  ? 420 LYS E N    1 
ATOM   7677  C  CA   . LYS E 1 213 ? 79.829  -55.180 24.659  1.00 64.56  ? 420 LYS E CA   1 
ATOM   7678  C  C    . LYS E 1 213 ? 80.258  -56.318 23.749  1.00 68.37  ? 420 LYS E C    1 
ATOM   7679  O  O    . LYS E 1 213 ? 80.549  -56.072 22.573  1.00 69.68  ? 420 LYS E O    1 
ATOM   7680  C  CB   . LYS E 1 213 ? 78.355  -54.894 24.384  1.00 30.00  ? 420 LYS E CB   1 
ATOM   7681  C  CG   . LYS E 1 213 ? 77.446  -56.110 24.475  1.00 30.00  ? 420 LYS E CG   1 
ATOM   7682  C  CD   . LYS E 1 213 ? 76.056  -55.893 23.967  1.00 30.00  ? 420 LYS E CD   1 
ATOM   7683  C  CE   . LYS E 1 213 ? 75.120  -57.001 24.389  1.00 30.00  ? 420 LYS E CE   1 
ATOM   7684  N  NZ   . LYS E 1 213 ? 73.814  -56.907 23.701  1.00 30.00  ? 420 LYS E NZ   1 
ATOM   7685  N  N    . ILE E 1 214 ? 80.300  -57.515 24.296  1.00 66.74  ? 421 ILE E N    1 
ATOM   7686  C  CA   . ILE E 1 214 ? 80.614  -58.707 23.520  1.00 65.99  ? 421 ILE E CA   1 
ATOM   7687  C  C    . ILE E 1 214 ? 79.311  -59.270 22.984  1.00 64.83  ? 421 ILE E C    1 
ATOM   7688  O  O    . ILE E 1 214 ? 78.336  -59.414 23.730  1.00 69.64  ? 421 ILE E O    1 
ATOM   7689  C  CB   . ILE E 1 214 ? 81.347  -59.747 24.385  1.00 65.94  ? 421 ILE E CB   1 
ATOM   7690  C  CG1  . ILE E 1 214 ? 82.778  -59.286 24.663  1.00 65.43  ? 421 ILE E CG1  1 
ATOM   7691  C  CG2  . ILE E 1 214 ? 81.284  -61.127 23.733  1.00 63.83  ? 421 ILE E CG2  1 
ATOM   7692  C  CD1  . ILE E 1 214 ? 83.454  -59.982 25.836  1.00 65.56  ? 421 ILE E CD1  1 
ATOM   7693  N  N    . ASN E 1 215 ? 79.278  -59.590 21.697  1.00 64.89  ? 422 ASN E N    1 
ATOM   7694  C  CA   . ASN E 1 215 ? 78.056  -60.114 21.109  1.00 66.32  ? 422 ASN E CA   1 
ATOM   7695  C  C    . ASN E 1 215 ? 78.203  -61.545 20.614  1.00 63.95  ? 422 ASN E C    1 
ATOM   7696  O  O    . ASN E 1 215 ? 77.267  -62.075 20.008  1.00 68.62  ? 422 ASN E O    1 
ATOM   7697  C  CB   . ASN E 1 215 ? 77.582  -59.192 19.989  1.00 63.68  ? 422 ASN E CB   1 
ATOM   7698  C  CG   . ASN E 1 215 ? 76.958  -57.924 20.519  1.00 69.13  ? 422 ASN E CG   1 
ATOM   7699  O  OD1  . ASN E 1 215 ? 75.920  -57.962 21.182  1.00 67.28  ? 422 ASN E OD1  1 
ATOM   7700  N  ND2  . ASN E 1 215 ? 77.586  -56.791 20.236  1.00 68.94  ? 422 ASN E ND2  1 
ATOM   7701  N  N    . ASP E 1 216 ? 79.331  -62.171 20.931  1.00 59.84  ? 423 ASP E N    1 
ATOM   7702  C  CA   . ASP E 1 216 ? 79.647  -63.523 20.412  1.00 59.07  ? 423 ASP E CA   1 
ATOM   7703  C  C    . ASP E 1 216 ? 78.607  -64.574 20.790  1.00 65.04  ? 423 ASP E C    1 
ATOM   7704  O  O    . ASP E 1 216 ? 77.912  -64.409 21.799  1.00 66.24  ? 423 ASP E O    1 
ATOM   7705  C  CB   . ASP E 1 216 ? 81.044  -63.949 20.861  1.00 62.03  ? 423 ASP E CB   1 
ATOM   7706  C  CG   . ASP E 1 216 ? 82.141  -62.978 20.464  1.00 68.49  ? 423 ASP E CG   1 
ATOM   7707  O  OD1  . ASP E 1 216 ? 81.871  -62.085 19.640  1.00 70.42  ? 423 ASP E OD1  1 
ATOM   7708  O  OD2  . ASP E 1 216 ? 83.257  -63.124 20.984  1.00 74.84  ? 423 ASP E OD2  1 
ATOM   7709  N  N    . ARG E 1 217 ? 78.547  -65.642 19.997  1.00 70.23  ? 424 ARG E N    1 
ATOM   7710  C  CA   . ARG E 1 217 ? 77.631  -66.738 20.267  1.00 72.72  ? 424 ARG E CA   1 
ATOM   7711  C  C    . ARG E 1 217 ? 78.001  -67.399 21.591  1.00 68.73  ? 424 ARG E C    1 
ATOM   7712  O  O    . ARG E 1 217 ? 79.179  -67.660 21.856  1.00 72.05  ? 424 ARG E O    1 
ATOM   7713  C  CB   . ARG E 1 217 ? 77.661  -67.756 19.117  1.00 61.50  ? 424 ARG E CB   1 
ATOM   7714  C  CG   . ARG E 1 217 ? 76.475  -68.707 19.123  1.00 69.11  ? 424 ARG E CG   1 
ATOM   7715  C  CD   . ARG E 1 217 ? 76.407  -69.619 17.894  1.00 67.89  ? 424 ARG E CD   1 
ATOM   7716  N  NE   . ARG E 1 217 ? 75.662  -70.842 18.190  1.00 67.87  ? 424 ARG E NE   1 
ATOM   7717  C  CZ   . ARG E 1 217 ? 74.349  -70.982 18.022  1.00 70.18  ? 424 ARG E CZ   1 
ATOM   7718  N  NH1  . ARG E 1 217 ? 73.639  -69.966 17.558  1.00 73.44  ? 424 ARG E NH1  1 
ATOM   7719  N  NH2  . ARG E 1 217 ? 73.744  -72.129 18.321  1.00 67.81  ? 424 ARG E NH2  1 
ATOM   7720  N  N    . PHE E 1 218 ? 76.992  -67.650 22.428  1.00 68.13  ? 425 PHE E N    1 
ATOM   7721  C  CA   . PHE E 1 218 ? 77.175  -68.307 23.726  1.00 66.65  ? 425 PHE E CA   1 
ATOM   7722  C  C    . PHE E 1 218 ? 75.897  -69.084 24.027  1.00 66.65  ? 425 PHE E C    1 
ATOM   7723  O  O    . PHE E 1 218 ? 74.841  -68.481 24.258  1.00 70.91  ? 425 PHE E O    1 
ATOM   7724  C  CB   . PHE E 1 218 ? 77.482  -67.275 24.816  1.00 65.86  ? 425 PHE E CB   1 
ATOM   7725  C  CG   . PHE E 1 218 ? 77.653  -67.857 26.193  1.00 66.04  ? 425 PHE E CG   1 
ATOM   7726  C  CD1  . PHE E 1 218 ? 78.869  -68.398 26.590  1.00 63.66  ? 425 PHE E CD1  1 
ATOM   7727  C  CD2  . PHE E 1 218 ? 76.602  -67.844 27.101  1.00 58.61  ? 425 PHE E CD2  1 
ATOM   7728  C  CE1  . PHE E 1 218 ? 79.023  -68.925 27.866  1.00 64.88  ? 425 PHE E CE1  1 
ATOM   7729  C  CE2  . PHE E 1 218 ? 76.763  -68.363 28.378  1.00 59.41  ? 425 PHE E CE2  1 
ATOM   7730  C  CZ   . PHE E 1 218 ? 77.968  -68.900 28.761  1.00 54.95  ? 425 PHE E CZ   1 
ATOM   7731  N  N    . GLU E 1 219 ? 75.980  -70.411 23.994  1.00 64.95  ? 426 GLU E N    1 
ATOM   7732  C  CA   . GLU E 1 219 ? 74.796  -71.250 24.110  1.00 64.76  ? 426 GLU E CA   1 
ATOM   7733  C  C    . GLU E 1 219 ? 74.512  -71.564 25.571  1.00 67.07  ? 426 GLU E C    1 
ATOM   7734  O  O    . GLU E 1 219 ? 75.424  -71.696 26.393  1.00 71.08  ? 426 GLU E O    1 
ATOM   7735  C  CB   . GLU E 1 219 ? 74.971  -72.551 23.324  1.00 68.22  ? 426 GLU E CB   1 
ATOM   7736  N  N    . PHE E 1 220 ? 73.233  -71.675 25.898  1.00 65.78  ? 427 PHE E N    1 
ATOM   7737  C  CA   . PHE E 1 220 ? 72.853  -72.079 27.238  1.00 65.45  ? 427 PHE E CA   1 
ATOM   7738  C  C    . PHE E 1 220 ? 71.723  -73.091 27.099  1.00 68.34  ? 427 PHE E C    1 
ATOM   7739  O  O    . PHE E 1 220 ? 70.791  -72.876 26.306  1.00 66.19  ? 427 PHE E O    1 
ATOM   7740  C  CB   . PHE E 1 220 ? 72.438  -70.886 28.121  1.00 57.75  ? 427 PHE E CB   1 
ATOM   7741  C  CG   . PHE E 1 220 ? 71.486  -69.920 27.457  1.00 67.30  ? 427 PHE E CG   1 
ATOM   7742  C  CD1  . PHE E 1 220 ? 71.955  -68.939 26.588  1.00 61.01  ? 427 PHE E CD1  1 
ATOM   7743  C  CD2  . PHE E 1 220 ? 70.118  -69.986 27.715  1.00 62.65  ? 427 PHE E CD2  1 
ATOM   7744  C  CE1  . PHE E 1 220 ? 71.077  -68.060 25.982  1.00 63.65  ? 427 PHE E CE1  1 
ATOM   7745  C  CE2  . PHE E 1 220 ? 69.238  -69.104 27.118  1.00 61.38  ? 427 PHE E CE2  1 
ATOM   7746  C  CZ   . PHE E 1 220 ? 69.723  -68.134 26.248  1.00 64.93  ? 427 PHE E CZ   1 
ATOM   7747  N  N    . PRO E 1 221 ? 71.793  -74.210 27.808  1.00 69.46  ? 428 PRO E N    1 
ATOM   7748  C  CA   . PRO E 1 221 ? 70.802  -75.272 27.644  1.00 60.90  ? 428 PRO E CA   1 
ATOM   7749  C  C    . PRO E 1 221 ? 69.546  -75.005 28.455  1.00 65.03  ? 428 PRO E C    1 
ATOM   7750  O  O    . PRO E 1 221 ? 69.477  -74.112 29.297  1.00 67.24  ? 428 PRO E O    1 
ATOM   7751  C  CB   . PRO E 1 221 ? 71.527  -76.511 28.169  1.00 59.00  ? 428 PRO E CB   1 
ATOM   7752  C  CG   . PRO E 1 221 ? 72.439  -75.976 29.189  1.00 66.46  ? 428 PRO E CG   1 
ATOM   7753  C  CD   . PRO E 1 221 ? 72.904  -74.631 28.671  1.00 65.92  ? 428 PRO E CD   1 
ATOM   7754  N  N    . GLU E 1 222 ? 68.547  -75.838 28.186  1.00 68.52  ? 429 GLU E N    1 
ATOM   7755  C  CA   . GLU E 1 222 ? 67.270  -75.778 28.878  1.00 66.78  ? 429 GLU E CA   1 
ATOM   7756  C  C    . GLU E 1 222 ? 67.299  -76.594 30.165  1.00 64.64  ? 429 GLU E C    1 
ATOM   7757  O  O    . GLU E 1 222 ? 66.572  -76.281 31.121  1.00 63.24  ? 429 GLU E O    1 
ATOM   7758  C  CB   . GLU E 1 222 ? 66.183  -76.270 27.921  1.00 68.42  ? 429 GLU E CB   1 
ATOM   7759  C  CG   . GLU E 1 222 ? 64.795  -76.361 28.486  1.00 72.80  ? 429 GLU E CG   1 
ATOM   7760  C  CD   . GLU E 1 222 ? 63.843  -76.953 27.484  1.00 75.42  ? 429 GLU E CD   1 
ATOM   7761  O  OE1  . GLU E 1 222 ? 64.272  -77.138 26.321  1.00 76.30  ? 429 GLU E OE1  1 
ATOM   7762  O  OE2  . GLU E 1 222 ? 62.682  -77.240 27.856  1.00 76.83  ? 429 GLU E OE2  1 
ATOM   7763  N  N    . GLN E 1 223 ? 68.132  -77.630 30.207  1.00 66.03  ? 430 GLN E N    1 
ATOM   7764  C  CA   . GLN E 1 223 ? 68.418  -78.387 31.418  1.00 68.23  ? 430 GLN E CA   1 
ATOM   7765  C  C    . GLN E 1 223 ? 69.913  -78.307 31.668  1.00 65.56  ? 430 GLN E C    1 
ATOM   7766  O  O    . GLN E 1 223 ? 70.712  -78.605 30.771  1.00 63.90  ? 430 GLN E O    1 
ATOM   7767  C  CB   . GLN E 1 223 ? 67.967  -79.846 31.297  1.00 64.93  ? 430 GLN E CB   1 
ATOM   7768  C  CG   . GLN E 1 223 ? 66.496  -79.996 30.932  1.00 73.35  ? 430 GLN E CG   1 
ATOM   7769  C  CD   . GLN E 1 223 ? 66.067  -81.451 30.774  1.00 80.54  ? 430 GLN E CD   1 
ATOM   7770  O  OE1  . GLN E 1 223 ? 66.396  -82.109 29.781  1.00 75.89  ? 430 GLN E OE1  1 
ATOM   7771  N  NE2  . GLN E 1 223 ? 65.324  -81.957 31.759  1.00 84.23  ? 430 GLN E NE2  1 
ATOM   7772  N  N    . LEU E 1 224 ? 70.286  -77.896 32.871  1.00 60.41  ? 431 LEU E N    1 
ATOM   7773  C  CA   . LEU E 1 224 ? 71.690  -77.677 33.207  1.00 61.28  ? 431 LEU E CA   1 
ATOM   7774  C  C    . LEU E 1 224 ? 72.088  -78.518 34.417  1.00 64.36  ? 431 LEU E C    1 
ATOM   7775  O  O    . LEU E 1 224 ? 71.594  -78.272 35.537  1.00 61.14  ? 431 LEU E O    1 
ATOM   7776  C  CB   . LEU E 1 224 ? 71.917  -76.189 33.464  1.00 61.90  ? 431 LEU E CB   1 
ATOM   7777  C  CG   . LEU E 1 224 ? 73.198  -75.588 34.033  1.00 60.07  ? 431 LEU E CG   1 
ATOM   7778  C  CD1  . LEU E 1 224 ? 74.353  -75.679 33.063  1.00 50.81  ? 431 LEU E CD1  1 
ATOM   7779  C  CD2  . LEU E 1 224 ? 72.903  -74.133 34.397  1.00 58.16  ? 431 LEU E CD2  1 
ATOM   7780  N  N    . PRO E 1 225 ? 72.939  -79.520 34.250  1.00 63.38  ? 432 PRO E N    1 
ATOM   7781  C  CA   . PRO E 1 225 ? 73.398  -80.298 35.408  1.00 61.31  ? 432 PRO E CA   1 
ATOM   7782  C  C    . PRO E 1 225 ? 74.707  -79.756 35.951  1.00 57.86  ? 432 PRO E C    1 
ATOM   7783  O  O    . PRO E 1 225 ? 75.669  -79.566 35.196  1.00 60.69  ? 432 PRO E O    1 
ATOM   7784  C  CB   . PRO E 1 225 ? 73.559  -81.705 34.832  1.00 59.58  ? 432 PRO E CB   1 
ATOM   7785  C  CG   . PRO E 1 225 ? 74.007  -81.445 33.384  1.00 63.51  ? 432 PRO E CG   1 
ATOM   7786  C  CD   . PRO E 1 225 ? 73.406  -80.091 32.972  1.00 68.08  ? 432 PRO E CD   1 
ATOM   7787  N  N    . LEU E 1 226 ? 74.753  -79.494 37.257  1.00 54.60  ? 433 LEU E N    1 
ATOM   7788  C  CA   . LEU E 1 226 ? 75.877  -78.792 37.861  1.00 58.50  ? 433 LEU E CA   1 
ATOM   7789  C  C    . LEU E 1 226 ? 76.603  -79.611 38.923  1.00 66.29  ? 433 LEU E C    1 
ATOM   7790  O  O    . LEU E 1 226 ? 77.524  -79.084 39.575  1.00 62.37  ? 433 LEU E O    1 
ATOM   7791  C  CB   . LEU E 1 226 ? 75.398  -77.471 38.457  1.00 55.45  ? 433 LEU E CB   1 
ATOM   7792  C  CG   . LEU E 1 226 ? 74.966  -76.477 37.384  1.00 56.12  ? 433 LEU E CG   1 
ATOM   7793  C  CD1  . LEU E 1 226 ? 74.372  -75.237 38.000  1.00 48.91  ? 433 LEU E CD1  1 
ATOM   7794  C  CD2  . LEU E 1 226 ? 76.164  -76.139 36.490  1.00 60.21  ? 433 LEU E CD2  1 
ATOM   7795  N  N    . ASP E 1 227 ? 76.236  -80.879 39.095  1.00 63.05  ? 434 ASP E N    1 
ATOM   7796  C  CA   . ASP E 1 227 ? 76.860  -81.712 40.155  1.00 63.00  ? 434 ASP E CA   1 
ATOM   7797  C  C    . ASP E 1 227 ? 78.380  -81.697 39.964  1.00 61.92  ? 434 ASP E C    1 
ATOM   7798  O  O    . ASP E 1 227 ? 79.093  -81.785 40.967  1.00 60.47  ? 434 ASP E O    1 
ATOM   7799  C  CB   . ASP E 1 227 ? 76.262  -83.120 40.153  1.00 56.52  ? 434 ASP E CB   1 
ATOM   7800  C  CG   . ASP E 1 227 ? 75.305  -83.422 41.292  1.00 65.93  ? 434 ASP E CG   1 
ATOM   7801  O  OD1  . ASP E 1 227 ? 75.092  -82.542 42.137  1.00 64.67  ? 434 ASP E OD1  1 
ATOM   7802  O  OD2  . ASP E 1 227 ? 74.794  -84.552 41.330  1.00 71.85  ? 434 ASP E OD2  1 
ATOM   7803  N  N    . GLU E 1 228 ? 78.849  -81.537 38.727  1.00 63.82  ? 435 GLU E N    1 
ATOM   7804  C  CA   . GLU E 1 228 ? 80.302  -81.578 38.419  1.00 64.66  ? 435 GLU E CA   1 
ATOM   7805  C  C    . GLU E 1 228 ? 81.041  -80.381 39.014  1.00 68.98  ? 435 GLU E C    1 
ATOM   7806  O  O    . GLU E 1 228 ? 82.278  -80.442 39.091  1.00 67.04  ? 435 GLU E O    1 
ATOM   7807  C  CB   . GLU E 1 228 ? 80.507  -81.575 36.906  1.00 67.15  ? 435 GLU E CB   1 
ATOM   7808  C  CG   . GLU E 1 228 ? 81.498  -82.616 36.424  1.00 69.57  ? 435 GLU E CG   1 
ATOM   7809  C  CD   . GLU E 1 228 ? 81.086  -84.049 36.708  1.00 78.85  ? 435 GLU E CD   1 
ATOM   7810  O  OE1  . GLU E 1 228 ? 79.967  -84.431 36.319  1.00 76.74  ? 435 GLU E OE1  1 
ATOM   7811  O  OE2  . GLU E 1 228 ? 81.887  -84.782 37.315  1.00 87.62  ? 435 GLU E OE2  1 
ATOM   7812  N  N    . PHE E 1 229 ? 80.320  -79.341 39.428  1.00 66.42  ? 436 PHE E N    1 
ATOM   7813  C  CA   . PHE E 1 229 ? 81.003  -78.109 39.896  1.00 65.41  ? 436 PHE E CA   1 
ATOM   7814  C  C    . PHE E 1 229 ? 80.890  -78.003 41.419  1.00 60.56  ? 436 PHE E C    1 
ATOM   7815  O  O    . PHE E 1 229 ? 81.361  -77.012 41.982  1.00 63.08  ? 436 PHE E O    1 
ATOM   7816  C  CB   . PHE E 1 229 ? 80.474  -76.938 39.072  1.00 60.57  ? 436 PHE E CB   1 
ATOM   7817  C  CG   . PHE E 1 229 ? 80.559  -77.205 37.594  1.00 59.78  ? 436 PHE E CG   1 
ATOM   7818  C  CD1  . PHE E 1 229 ? 81.789  -77.285 36.967  1.00 62.44  ? 436 PHE E CD1  1 
ATOM   7819  C  CD2  . PHE E 1 229 ? 79.421  -77.449 36.849  1.00 60.39  ? 436 PHE E CD2  1 
ATOM   7820  C  CE1  . PHE E 1 229 ? 81.875  -77.570 35.617  1.00 57.82  ? 436 PHE E CE1  1 
ATOM   7821  C  CE2  . PHE E 1 229 ? 79.507  -77.725 35.496  1.00 60.48  ? 436 PHE E CE2  1 
ATOM   7822  C  CZ   . PHE E 1 229 ? 80.734  -77.778 34.883  1.00 56.95  ? 436 PHE E CZ   1 
ATOM   7823  N  N    . LEU E 1 230 ? 80.323  -79.019 42.057  1.00 59.85  ? 437 LEU E N    1 
ATOM   7824  C  CA   . LEU E 1 230 ? 80.247  -79.053 43.533  1.00 56.75  ? 437 LEU E CA   1 
ATOM   7825  C  C    . LEU E 1 230 ? 81.448  -79.818 44.075  1.00 59.85  ? 437 LEU E C    1 
ATOM   7826  O  O    . LEU E 1 230 ? 81.970  -80.679 43.355  1.00 62.54  ? 437 LEU E O    1 
ATOM   7827  C  CB   . LEU E 1 230 ? 78.962  -79.771 43.938  1.00 58.42  ? 437 LEU E CB   1 
ATOM   7828  C  CG   . LEU E 1 230 ? 77.665  -78.990 43.765  1.00 61.04  ? 437 LEU E CG   1 
ATOM   7829  C  CD1  . LEU E 1 230 ? 76.472  -79.908 43.954  1.00 55.00  ? 437 LEU E CD1  1 
ATOM   7830  C  CD2  . LEU E 1 230 ? 77.597  -77.839 44.750  1.00 56.86  ? 437 LEU E CD2  1 
ATOM   7831  N  N    . GLN E 1 231 ? 81.867  -79.507 45.296  1.00 57.75  ? 438 GLN E N    1 
ATOM   7832  C  CA   . GLN E 1 231 ? 82.954  -80.285 45.929  1.00 56.12  ? 438 GLN E CA   1 
ATOM   7833  C  C    . GLN E 1 231 ? 82.363  -81.627 46.342  1.00 67.87  ? 438 GLN E C    1 
ATOM   7834  O  O    . GLN E 1 231 ? 83.066  -82.636 46.198  1.00 73.30  ? 438 GLN E O    1 
ATOM   7835  C  CB   . GLN E 1 231 ? 83.531  -79.535 47.124  1.00 61.23  ? 438 GLN E CB   1 
ATOM   7836  C  CG   . GLN E 1 231 ? 84.896  -80.036 47.566  1.00 62.30  ? 438 GLN E CG   1 
ATOM   7837  C  CD   . GLN E 1 231 ? 85.972  -79.728 46.557  1.00 65.59  ? 438 GLN E CD   1 
ATOM   7838  O  OE1  . GLN E 1 231 ? 86.391  -78.589 46.404  1.00 66.11  ? 438 GLN E OE1  1 
ATOM   7839  N  NE2  . GLN E 1 231 ? 86.437  -80.750 45.860  1.00 68.70  ? 438 GLN E NE2  1 
ATOM   7840  N  N    . LYS E 1 232 ? 81.110  -81.633 46.811  1.00 66.48  ? 439 LYS E N    1 
ATOM   7841  C  CA   . LYS E 1 232 ? 80.429  -82.902 47.179  1.00 65.81  ? 439 LYS E CA   1 
ATOM   7842  C  C    . LYS E 1 232 ? 79.027  -82.959 46.575  1.00 68.14  ? 439 LYS E C    1 
ATOM   7843  O  O    . LYS E 1 232 ? 78.254  -82.019 46.794  1.00 67.75  ? 439 LYS E O    1 
ATOM   7844  C  CB   . LYS E 1 232 ? 80.349  -83.072 48.696  1.00 62.63  ? 439 LYS E CB   1 
ATOM   7845  C  CG   . LYS E 1 232 ? 80.576  -84.490 49.196  1.00 75.08  ? 439 LYS E CG   1 
ATOM   7846  C  CD   . LYS E 1 232 ? 79.965  -84.750 50.553  1.00 69.02  ? 439 LYS E CD   1 
ATOM   7847  C  CE   . LYS E 1 232 ? 80.345  -86.097 51.126  1.00 69.26  ? 439 LYS E CE   1 
ATOM   7848  N  NZ   . LYS E 1 232 ? 80.144  -87.186 50.141  1.00 79.54  ? 439 LYS E NZ   1 
ATOM   7849  N  N    . THR E 1 233 ? 78.719  -84.043 45.868  1.00 71.41  ? 440 THR E N    1 
ATOM   7850  C  CA   . THR E 1 233 ? 77.397  -84.248 45.289  1.00 64.06  ? 440 THR E CA   1 
ATOM   7851  C  C    . THR E 1 233 ? 76.482  -84.965 46.269  1.00 68.26  ? 440 THR E C    1 
ATOM   7852  O  O    . THR E 1 233 ? 76.915  -85.868 46.992  1.00 74.83  ? 440 THR E O    1 
ATOM   7853  C  CB   . THR E 1 233 ? 77.501  -85.071 44.008  1.00 67.74  ? 440 THR E CB   1 
ATOM   7854  O  OG1  . THR E 1 233 ? 78.138  -86.316 44.305  1.00 70.78  ? 440 THR E OG1  1 
ATOM   7855  C  CG2  . THR E 1 233 ? 78.307  -84.334 42.963  1.00 54.56  ? 440 THR E CG2  1 
ATOM   7856  N  N    . ASP E 1 234 ? 75.204  -84.567 46.277  1.00 73.45  ? 441 ASP E N    1 
ATOM   7857  C  CA   . ASP E 1 234 ? 74.180  -85.248 47.063  1.00 73.63  ? 441 ASP E CA   1 
ATOM   7858  C  C    . ASP E 1 234 ? 73.480  -86.267 46.169  1.00 73.91  ? 441 ASP E C    1 
ATOM   7859  O  O    . ASP E 1 234 ? 72.737  -85.866 45.255  1.00 71.33  ? 441 ASP E O    1 
ATOM   7860  C  CB   . ASP E 1 234 ? 73.173  -84.244 47.624  1.00 67.70  ? 441 ASP E CB   1 
ATOM   7861  C  CG   . ASP E 1 234 ? 72.201  -84.866 48.624  1.00 74.28  ? 441 ASP E CG   1 
ATOM   7862  O  OD1  . ASP E 1 234 ? 71.877  -86.067 48.500  1.00 72.74  ? 441 ASP E OD1  1 
ATOM   7863  O  OD2  . ASP E 1 234 ? 71.736  -84.143 49.536  1.00 77.95  ? 441 ASP E OD2  1 
ATOM   7864  N  N    . PRO E 1 235 ? 73.660  -87.575 46.391  1.00 78.65  ? 442 PRO E N    1 
ATOM   7865  C  CA   . PRO E 1 235 ? 72.990  -88.552 45.510  1.00 74.31  ? 442 PRO E CA   1 
ATOM   7866  C  C    . PRO E 1 235 ? 71.475  -88.465 45.582  1.00 75.67  ? 442 PRO E C    1 
ATOM   7867  O  O    . PRO E 1 235 ? 70.805  -88.627 44.550  1.00 78.38  ? 442 PRO E O    1 
ATOM   7868  C  CB   . PRO E 1 235 ? 73.516  -89.905 46.010  1.00 76.51  ? 442 PRO E CB   1 
ATOM   7869  C  CG   . PRO E 1 235 ? 74.724  -89.576 46.872  1.00 75.56  ? 442 PRO E CG   1 
ATOM   7870  C  CD   . PRO E 1 235 ? 74.422  -88.231 47.469  1.00 73.25  ? 442 PRO E CD   1 
ATOM   7871  N  N    . LYS E 1 236 ? 70.919  -88.161 46.758  1.00 71.42  ? 443 LYS E N    1 
ATOM   7872  C  CA   . LYS E 1 236 ? 69.481  -87.993 46.949  1.00 72.56  ? 443 LYS E CA   1 
ATOM   7873  C  C    . LYS E 1 236 ? 68.965  -86.619 46.513  1.00 74.14  ? 443 LYS E C    1 
ATOM   7874  O  O    . LYS E 1 236 ? 67.802  -86.303 46.805  1.00 66.04  ? 443 LYS E O    1 
ATOM   7875  C  CB   . LYS E 1 236 ? 69.112  -88.234 48.421  1.00 68.08  ? 443 LYS E CB   1 
ATOM   7876  N  N    . ASP E 1 237 ? 69.804  -85.790 45.854  1.00 71.82  ? 444 ASP E N    1 
ATOM   7877  C  CA   . ASP E 1 237 ? 69.416  -84.474 45.347  1.00 64.20  ? 444 ASP E CA   1 
ATOM   7878  C  C    . ASP E 1 237 ? 70.447  -83.961 44.348  1.00 70.38  ? 444 ASP E C    1 
ATOM   7879  O  O    . ASP E 1 237 ? 71.335  -83.174 44.709  1.00 64.48  ? 444 ASP E O    1 
ATOM   7880  C  CB   . ASP E 1 237 ? 69.256  -83.451 46.471  1.00 62.66  ? 444 ASP E CB   1 
ATOM   7881  C  CG   . ASP E 1 237 ? 68.719  -82.105 45.969  1.00 63.91  ? 444 ASP E CG   1 
ATOM   7882  O  OD1  . ASP E 1 237 ? 68.655  -81.891 44.741  1.00 65.27  ? 444 ASP E OD1  1 
ATOM   7883  O  OD2  . ASP E 1 237 ? 68.336  -81.257 46.805  1.00 59.83  ? 444 ASP E OD2  1 
ATOM   7884  N  N    . PRO E 1 238 ? 70.339  -84.353 43.083  1.00 72.25  ? 445 PRO E N    1 
ATOM   7885  C  CA   . PRO E 1 238 ? 71.275  -83.849 42.074  1.00 70.67  ? 445 PRO E CA   1 
ATOM   7886  C  C    . PRO E 1 238 ? 71.076  -82.362 41.799  1.00 72.19  ? 445 PRO E C    1 
ATOM   7887  O  O    . PRO E 1 238 ? 69.956  -81.837 41.810  1.00 67.62  ? 445 PRO E O    1 
ATOM   7888  C  CB   . PRO E 1 238 ? 70.947  -84.689 40.834  1.00 70.98  ? 445 PRO E CB   1 
ATOM   7889  C  CG   . PRO E 1 238 ? 70.111  -85.849 41.348  1.00 68.79  ? 445 PRO E CG   1 
ATOM   7890  C  CD   . PRO E 1 238 ? 69.400  -85.347 42.537  1.00 67.37  ? 445 PRO E CD   1 
ATOM   7891  N  N    . ALA E 1 239 ? 72.193  -81.680 41.541  1.00 68.23  ? 446 ALA E N    1 
ATOM   7892  C  CA   . ALA E 1 239 ? 72.168  -80.261 41.193  1.00 65.43  ? 446 ALA E CA   1 
ATOM   7893  C  C    . ALA E 1 239 ? 71.762  -80.069 39.728  1.00 63.13  ? 446 ALA E C    1 
ATOM   7894  O  O    . ALA E 1 239 ? 72.518  -79.566 38.895  1.00 61.56  ? 446 ALA E O    1 
ATOM   7895  C  CB   . ALA E 1 239 ? 73.525  -79.635 41.475  1.00 62.68  ? 446 ALA E CB   1 
ATOM   7896  N  N    . ASN E 1 240 ? 70.537  -80.482 39.414  1.00 63.93  ? 447 ASN E N    1 
ATOM   7897  C  CA   . ASN E 1 240 ? 69.981  -80.289 38.078  1.00 68.14  ? 447 ASN E CA   1 
ATOM   7898  C  C    . ASN E 1 240 ? 69.124  -79.031 38.076  1.00 61.95  ? 447 ASN E C    1 
ATOM   7899  O  O    . ASN E 1 240 ? 68.331  -78.817 39.002  1.00 63.84  ? 447 ASN E O    1 
ATOM   7900  C  CB   . ASN E 1 240 ? 69.158  -81.502 37.638  1.00 66.24  ? 447 ASN E CB   1 
ATOM   7901  C  CG   . ASN E 1 240 ? 70.019  -82.731 37.416  1.00 71.08  ? 447 ASN E CG   1 
ATOM   7902  O  OD1  . ASN E 1 240 ? 71.104  -82.645 36.823  1.00 64.99  ? 447 ASN E OD1  1 
ATOM   7903  N  ND2  . ASN E 1 240 ? 69.553  -83.881 37.911  1.00 66.67  ? 447 ASN E ND2  1 
ATOM   7904  N  N    . TYR E 1 241 ? 69.307  -78.229 37.026  1.00 57.11  ? 448 TYR E N    1 
ATOM   7905  C  CA   . TYR E 1 241 ? 68.623  -76.918 36.969  1.00 63.78  ? 448 TYR E CA   1 
ATOM   7906  C  C    . TYR E 1 241 ? 67.788  -76.762 35.701  1.00 62.22  ? 448 TYR E C    1 
ATOM   7907  O  O    . TYR E 1 241 ? 68.267  -77.090 34.621  1.00 65.69  ? 448 TYR E O    1 
ATOM   7908  C  CB   . TYR E 1 241 ? 69.645  -75.795 37.157  1.00 59.22  ? 448 TYR E CB   1 
ATOM   7909  C  CG   . TYR E 1 241 ? 70.038  -75.593 38.595  1.00 59.90  ? 448 TYR E CG   1 
ATOM   7910  C  CD1  . TYR E 1 241 ? 70.948  -76.434 39.212  1.00 57.01  ? 448 TYR E CD1  1 
ATOM   7911  C  CD2  . TYR E 1 241 ? 69.475  -74.581 39.347  1.00 59.97  ? 448 TYR E CD2  1 
ATOM   7912  C  CE1  . TYR E 1 241 ? 71.289  -76.279 40.541  1.00 60.91  ? 448 TYR E CE1  1 
ATOM   7913  C  CE2  . TYR E 1 241 ? 69.807  -74.407 40.677  1.00 57.41  ? 448 TYR E CE2  1 
ATOM   7914  C  CZ   . TYR E 1 241 ? 70.717  -75.259 41.273  1.00 56.85  ? 448 TYR E CZ   1 
ATOM   7915  O  OH   . TYR E 1 241 ? 71.043  -75.103 42.582  1.00 55.15  ? 448 TYR E OH   1 
ATOM   7916  N  N    . ILE E 1 242 ? 66.576  -76.253 35.855  1.00 63.41  ? 449 ILE E N    1 
ATOM   7917  C  CA   . ILE E 1 242 ? 65.620  -76.019 34.777  1.00 67.82  ? 449 ILE E CA   1 
ATOM   7918  C  C    . ILE E 1 242 ? 65.639  -74.534 34.419  1.00 62.56  ? 449 ILE E C    1 
ATOM   7919  O  O    . ILE E 1 242 ? 65.490  -73.681 35.304  1.00 59.45  ? 449 ILE E O    1 
ATOM   7920  C  CB   . ILE E 1 242 ? 64.208  -76.454 35.218  1.00 62.02  ? 449 ILE E CB   1 
ATOM   7921  C  CG1  . ILE E 1 242 ? 64.204  -77.926 35.606  1.00 60.68  ? 449 ILE E CG1  1 
ATOM   7922  C  CG2  . ILE E 1 242 ? 63.165  -76.153 34.144  1.00 63.21  ? 449 ILE E CG2  1 
ATOM   7923  C  CD1  . ILE E 1 242 ? 64.936  -78.781 34.654  1.00 62.91  ? 449 ILE E CD1  1 
ATOM   7924  N  N    . LEU E 1 243 ? 65.796  -74.216 33.130  1.00 60.47  ? 450 LEU E N    1 
ATOM   7925  C  CA   . LEU E 1 243 ? 65.816  -72.809 32.709  1.00 62.91  ? 450 LEU E CA   1 
ATOM   7926  C  C    . LEU E 1 243 ? 64.461  -72.131 32.930  1.00 58.61  ? 450 LEU E C    1 
ATOM   7927  O  O    . LEU E 1 243 ? 63.413  -72.680 32.584  1.00 63.54  ? 450 LEU E O    1 
ATOM   7928  C  CB   . LEU E 1 243 ? 66.222  -72.691 31.240  1.00 62.25  ? 450 LEU E CB   1 
ATOM   7929  C  CG   . LEU E 1 243 ? 66.155  -71.267 30.668  1.00 63.58  ? 450 LEU E CG   1 
ATOM   7930  C  CD1  . LEU E 1 243 ? 67.131  -70.361 31.388  1.00 62.19  ? 450 LEU E CD1  1 
ATOM   7931  C  CD2  . LEU E 1 243 ? 66.454  -71.265 29.194  1.00 59.55  ? 450 LEU E CD2  1 
ATOM   7932  N  N    . HIS E 1 244 ? 64.486  -70.922 33.495  1.00 61.78  ? 451 HIS E N    1 
ATOM   7933  C  CA   . HIS E 1 244 ? 63.282  -70.159 33.828  1.00 55.98  ? 451 HIS E CA   1 
ATOM   7934  C  C    . HIS E 1 244 ? 63.176  -68.838 33.092  1.00 62.09  ? 451 HIS E C    1 
ATOM   7935  O  O    . HIS E 1 244 ? 62.071  -68.429 32.737  1.00 63.45  ? 451 HIS E O    1 
ATOM   7936  C  CB   . HIS E 1 244 ? 63.230  -69.866 35.332  1.00 57.08  ? 451 HIS E CB   1 
ATOM   7937  C  CG   . HIS E 1 244 ? 61.877  -69.473 35.838  1.00 62.02  ? 451 HIS E CG   1 
ATOM   7938  N  ND1  . HIS E 1 244 ? 61.703  -68.635 36.917  1.00 60.05  ? 451 HIS E ND1  1 
ATOM   7939  C  CD2  . HIS E 1 244 ? 60.634  -69.832 35.441  1.00 64.02  ? 451 HIS E CD2  1 
ATOM   7940  C  CE1  . HIS E 1 244 ? 60.413  -68.484 37.156  1.00 60.21  ? 451 HIS E CE1  1 
ATOM   7941  N  NE2  . HIS E 1 244 ? 59.743  -69.201 36.273  1.00 61.49  ? 451 HIS E NE2  1 
ATOM   7942  N  N    . ALA E 1 245 ? 64.286  -68.114 32.998  1.00 64.30  ? 452 ALA E N    1 
ATOM   7943  C  CA   . ALA E 1 245 ? 64.187  -66.754 32.436  1.00 61.14  ? 452 ALA E CA   1 
ATOM   7944  C  C    . ALA E 1 245 ? 65.439  -66.352 31.673  1.00 61.70  ? 452 ALA E C    1 
ATOM   7945  O  O    . ALA E 1 245 ? 66.533  -66.778 32.055  1.00 64.27  ? 452 ALA E O    1 
ATOM   7946  C  CB   . ALA E 1 245 ? 63.919  -65.792 33.552  1.00 57.45  ? 452 ALA E CB   1 
ATOM   7947  N  N    . VAL E 1 246 ? 65.247  -65.546 30.631  1.00 58.14  ? 453 VAL E N    1 
ATOM   7948  C  CA   . VAL E 1 246 ? 66.373  -65.078 29.779  1.00 63.70  ? 453 VAL E CA   1 
ATOM   7949  C  C    . VAL E 1 246 ? 66.266  -63.558 29.682  1.00 64.98  ? 453 VAL E C    1 
ATOM   7950  O  O    . VAL E 1 246 ? 65.483  -63.069 28.856  1.00 63.27  ? 453 VAL E O    1 
ATOM   7951  C  CB   . VAL E 1 246 ? 66.330  -65.731 28.385  1.00 65.09  ? 453 VAL E CB   1 
ATOM   7952  C  CG1  . VAL E 1 246 ? 67.544  -65.381 27.553  1.00 60.74  ? 453 VAL E CG1  1 
ATOM   7953  C  CG2  . VAL E 1 246 ? 66.143  -67.238 28.446  1.00 65.96  ? 453 VAL E CG2  1 
ATOM   7954  N  N    . LEU E 1 247 ? 66.991  -62.850 30.540  1.00 58.81  ? 454 LEU E N    1 
ATOM   7955  C  CA   . LEU E 1 247 ? 67.005  -61.368 30.486  1.00 59.75  ? 454 LEU E CA   1 
ATOM   7956  C  C    . LEU E 1 247 ? 67.873  -60.999 29.289  1.00 60.51  ? 454 LEU E C    1 
ATOM   7957  O  O    . LEU E 1 247 ? 69.029  -61.426 29.255  1.00 58.38  ? 454 LEU E O    1 
ATOM   7958  C  CB   . LEU E 1 247 ? 67.448  -60.827 31.846  1.00 56.98  ? 454 LEU E CB   1 
ATOM   7959  C  CG   . LEU E 1 247 ? 66.399  -60.998 32.944  1.00 55.70  ? 454 LEU E CG   1 
ATOM   7960  C  CD1  . LEU E 1 247 ? 66.654  -62.234 33.790  1.00 55.15  ? 454 LEU E CD1  1 
ATOM   7961  C  CD2  . LEU E 1 247 ? 66.303  -59.766 33.819  1.00 51.98  ? 454 LEU E CD2  1 
ATOM   7962  N  N    . VAL E 1 248 ? 67.340  -60.207 28.365  1.00 60.58  ? 455 VAL E N    1 
ATOM   7963  C  CA   . VAL E 1 248 ? 67.962  -59.996 27.066  1.00 58.38  ? 455 VAL E CA   1 
ATOM   7964  C  C    . VAL E 1 248 ? 68.242  -58.513 26.894  1.00 59.23  ? 455 VAL E C    1 
ATOM   7965  O  O    . VAL E 1 248 ? 67.360  -57.682 27.133  1.00 59.92  ? 455 VAL E O    1 
ATOM   7966  C  CB   . VAL E 1 248 ? 67.065  -60.520 25.932  1.00 63.38  ? 455 VAL E CB   1 
ATOM   7967  C  CG1  . VAL E 1 248 ? 67.528  -59.986 24.581  1.00 62.35  ? 455 VAL E CG1  1 
ATOM   7968  C  CG2  . VAL E 1 248 ? 67.016  -62.048 25.965  1.00 60.21  ? 455 VAL E CG2  1 
ATOM   7969  N  N    . HIS E 1 249 ? 69.464  -58.193 26.469  1.00 62.13  ? 456 HIS E N    1 
ATOM   7970  C  CA   . HIS E 1 249 ? 69.907  -56.829 26.202  1.00 63.06  ? 456 HIS E CA   1 
ATOM   7971  C  C    . HIS E 1 249 ? 70.233  -56.663 24.719  1.00 65.26  ? 456 HIS E C    1 
ATOM   7972  O  O    . HIS E 1 249 ? 70.949  -57.486 24.133  1.00 65.55  ? 456 HIS E O    1 
ATOM   7973  C  CB   . HIS E 1 249 ? 71.134  -56.472 27.046  1.00 55.56  ? 456 HIS E CB   1 
ATOM   7974  C  CG   . HIS E 1 249 ? 71.667  -55.112 26.759  1.00 63.85  ? 456 HIS E CG   1 
ATOM   7975  N  ND1  . HIS E 1 249 ? 72.603  -54.874 25.775  1.00 61.74  ? 456 HIS E ND1  1 
ATOM   7976  C  CD2  . HIS E 1 249 ? 71.363  -53.905 27.295  1.00 58.20  ? 456 HIS E CD2  1 
ATOM   7977  C  CE1  . HIS E 1 249 ? 72.870  -53.581 25.734  1.00 62.73  ? 456 HIS E CE1  1 
ATOM   7978  N  NE2  . HIS E 1 249 ? 72.129  -52.971 26.643  1.00 61.90  ? 456 HIS E NE2  1 
ATOM   7979  N  N    . SER E 1 250 ? 69.707  -55.601 24.113  1.00 64.16  ? 457 SER E N    1 
ATOM   7980  C  CA   . SER E 1 250 ? 69.960  -55.285 22.712  1.00 63.86  ? 457 SER E CA   1 
ATOM   7981  C  C    . SER E 1 250 ? 70.627  -53.923 22.648  1.00 65.69  ? 457 SER E C    1 
ATOM   7982  O  O    . SER E 1 250 ? 70.066  -52.929 23.124  1.00 58.86  ? 457 SER E O    1 
ATOM   7983  C  CB   . SER E 1 250 ? 68.673  -55.281 21.889  1.00 64.43  ? 457 SER E CB   1 
ATOM   7984  O  OG   . SER E 1 250 ? 67.675  -54.491 22.513  1.00 72.34  ? 457 SER E OG   1 
ATOM   7985  N  N    . GLY E 1 251 ? 71.821  -53.886 22.077  1.00 67.37  ? 458 GLY E N    1 
ATOM   7986  C  CA   . GLY E 1 251 ? 72.535  -52.642 21.954  1.00 68.62  ? 458 GLY E CA   1 
ATOM   7987  C  C    . GLY E 1 251 ? 73.994  -52.812 22.297  1.00 74.29  ? 458 GLY E C    1 
ATOM   7988  O  O    . GLY E 1 251 ? 74.590  -53.852 22.010  1.00 76.31  ? 458 GLY E O    1 
ATOM   7989  N  N    . ASP E 1 252 ? 74.548  -51.756 22.881  1.00 77.43  ? 459 ASP E N    1 
ATOM   7990  C  CA   . ASP E 1 252 ? 75.987  -51.742 23.207  1.00 82.22  ? 459 ASP E CA   1 
ATOM   7991  C  C    . ASP E 1 252 ? 76.176  -51.248 24.638  1.00 82.20  ? 459 ASP E C    1 
ATOM   7992  O  O    . ASP E 1 252 ? 75.170  -51.060 25.346  1.00 77.26  ? 459 ASP E O    1 
ATOM   7993  C  CB   . ASP E 1 252 ? 76.719  -50.830 22.223  1.00 82.50  ? 459 ASP E CB   1 
ATOM   7994  C  CG   . ASP E 1 252 ? 76.381  -49.355 22.367  1.00 87.46  ? 459 ASP E CG   1 
ATOM   7995  O  OD1  . ASP E 1 252 ? 75.201  -49.003 22.208  1.00 86.92  ? 459 ASP E OD1  1 
ATOM   7996  O  OD2  . ASP E 1 252 ? 77.307  -48.570 22.632  1.00 92.40  ? 459 ASP E OD2  1 
ATOM   7997  N  N    . ASN E 1 253 ? 77.430  -51.041 25.036  1.00 86.80  ? 460 ASN E N    1 
ATOM   7998  C  CA   . ASN E 1 253 ? 77.722  -50.495 26.383  1.00 86.67  ? 460 ASN E CA   1 
ATOM   7999  C  C    . ASN E 1 253 ? 76.915  -49.215 26.568  1.00 88.07  ? 460 ASN E C    1 
ATOM   8000  O  O    . ASN E 1 253 ? 76.138  -49.154 27.541  1.00 79.29  ? 460 ASN E O    1 
ATOM   8001  C  CB   . ASN E 1 253 ? 79.216  -50.213 26.537  1.00 83.84  ? 460 ASN E CB   1 
ATOM   8002  C  CG   . ASN E 1 253 ? 79.543  -49.334 27.725  1.00 92.83  ? 460 ASN E CG   1 
ATOM   8003  O  OD1  . ASN E 1 253 ? 79.877  -48.162 27.562  1.00 91.28  ? 460 ASN E OD1  1 
ATOM   8004  N  ND2  . ASN E 1 253 ? 79.441  -49.884 28.924  1.00 104.54 ? 460 ASN E ND2  1 
ATOM   8005  N  N    . HIS E 1 254 ? 77.090  -48.253 25.659  1.00 84.08  ? 461 HIS E N    1 
ATOM   8006  C  CA   . HIS E 1 254 ? 76.427  -46.931 25.779  1.00 83.59  ? 461 HIS E CA   1 
ATOM   8007  C  C    . HIS E 1 254 ? 74.941  -47.088 26.074  1.00 81.41  ? 461 HIS E C    1 
ATOM   8008  O  O    . HIS E 1 254 ? 74.469  -46.468 27.040  1.00 83.78  ? 461 HIS E O    1 
ATOM   8009  N  N    . GLY E 1 255 ? 74.231  -47.862 25.259  1.00 82.29  ? 462 GLY E N    1 
ATOM   8010  C  CA   . GLY E 1 255 ? 72.777  -47.944 25.460  1.00 77.05  ? 462 GLY E CA   1 
ATOM   8011  C  C    . GLY E 1 255 ? 72.105  -49.070 24.711  1.00 76.39  ? 462 GLY E C    1 
ATOM   8012  O  O    . GLY E 1 255 ? 72.767  -49.752 23.922  1.00 76.33  ? 462 GLY E O    1 
ATOM   8013  N  N    . GLY E 1 256 ? 70.814  -49.246 24.966  1.00 69.45  ? 463 GLY E N    1 
ATOM   8014  C  CA   . GLY E 1 256 ? 70.068  -50.283 24.281  1.00 64.35  ? 463 GLY E CA   1 
ATOM   8015  C  C    . GLY E 1 256 ? 68.732  -50.521 24.938  1.00 66.70  ? 463 GLY E C    1 
ATOM   8016  O  O    . GLY E 1 256 ? 68.166  -49.622 25.583  1.00 61.39  ? 463 GLY E O    1 
ATOM   8017  N  N    . HIS E 1 257 ? 68.232  -51.751 24.767  1.00 64.03  ? 464 HIS E N    1 
ATOM   8018  C  CA   . HIS E 1 257 ? 66.917  -52.133 25.260  1.00 62.22  ? 464 HIS E CA   1 
ATOM   8019  C  C    . HIS E 1 257 ? 66.992  -53.482 25.958  1.00 63.14  ? 464 HIS E C    1 
ATOM   8020  O  O    . HIS E 1 257 ? 67.813  -54.340 25.610  1.00 64.60  ? 464 HIS E O    1 
ATOM   8021  C  CB   . HIS E 1 257 ? 65.880  -52.191 24.124  1.00 62.12  ? 464 HIS E CB   1 
ATOM   8022  C  CG   . HIS E 1 257 ? 64.471  -52.349 24.607  1.00 64.70  ? 464 HIS E CG   1 
ATOM   8023  N  ND1  . HIS E 1 257 ? 63.774  -51.328 25.222  1.00 64.14  ? 464 HIS E ND1  1 
ATOM   8024  C  CD2  . HIS E 1 257 ? 63.633  -53.412 24.577  1.00 61.39  ? 464 HIS E CD2  1 
ATOM   8025  C  CE1  . HIS E 1 257 ? 62.564  -51.754 25.544  1.00 60.82  ? 464 HIS E CE1  1 
ATOM   8026  N  NE2  . HIS E 1 257 ? 62.456  -53.018 25.172  1.00 63.65  ? 464 HIS E NE2  1 
ATOM   8027  N  N    . TYR E 1 258 ? 66.119  -53.656 26.949  1.00 61.49  ? 465 TYR E N    1 
ATOM   8028  C  CA   . TYR E 1 258 ? 66.053  -54.853 27.779  1.00 60.24  ? 465 TYR E CA   1 
ATOM   8029  C  C    . TYR E 1 258 ? 64.678  -55.483 27.628  1.00 61.24  ? 465 TYR E C    1 
ATOM   8030  O  O    . TYR E 1 258 ? 63.666  -54.775 27.643  1.00 60.10  ? 465 TYR E O    1 
ATOM   8031  C  CB   . TYR E 1 258 ? 66.278  -54.525 29.269  1.00 56.71  ? 465 TYR E CB   1 
ATOM   8032  C  CG   . TYR E 1 258 ? 67.691  -54.709 29.778  1.00 57.02  ? 465 TYR E CG   1 
ATOM   8033  C  CD1  . TYR E 1 258 ? 68.251  -55.965 29.885  1.00 55.75  ? 465 TYR E CD1  1 
ATOM   8034  C  CD2  . TYR E 1 258 ? 68.456  -53.617 30.177  1.00 59.74  ? 465 TYR E CD2  1 
ATOM   8035  C  CE1  . TYR E 1 258 ? 69.535  -56.140 30.361  1.00 54.89  ? 465 TYR E CE1  1 
ATOM   8036  C  CE2  . TYR E 1 258 ? 69.738  -53.782 30.664  1.00 56.07  ? 465 TYR E CE2  1 
ATOM   8037  C  CZ   . TYR E 1 258 ? 70.274  -55.050 30.759  1.00 58.99  ? 465 TYR E CZ   1 
ATOM   8038  O  OH   . TYR E 1 258 ? 71.565  -55.226 31.231  1.00 59.43  ? 465 TYR E OH   1 
ATOM   8039  N  N    . VAL E 1 259 ? 64.657  -56.811 27.503  1.00 61.94  ? 466 VAL E N    1 
ATOM   8040  C  CA   . VAL E 1 259 ? 63.386  -57.590 27.458  1.00 59.34  ? 466 VAL E CA   1 
ATOM   8041  C  C    . VAL E 1 259 ? 63.615  -58.847 28.304  1.00 63.51  ? 466 VAL E C    1 
ATOM   8042  O  O    . VAL E 1 259 ? 64.776  -59.166 28.594  1.00 62.30  ? 466 VAL E O    1 
ATOM   8043  C  CB   . VAL E 1 259 ? 62.935  -57.968 26.031  1.00 63.12  ? 466 VAL E CB   1 
ATOM   8044  C  CG1  . VAL E 1 259 ? 62.753  -56.781 25.108  1.00 54.79  ? 466 VAL E CG1  1 
ATOM   8045  C  CG2  . VAL E 1 259 ? 63.819  -59.014 25.381  1.00 55.21  ? 466 VAL E CG2  1 
ATOM   8046  N  N    . VAL E 1 260 ? 62.546  -59.539 28.686  1.00 59.36  ? 467 VAL E N    1 
ATOM   8047  C  CA   . VAL E 1 260 ? 62.721  -60.813 29.438  1.00 61.03  ? 467 VAL E CA   1 
ATOM   8048  C  C    . VAL E 1 260 ? 61.840  -61.920 28.858  1.00 62.63  ? 467 VAL E C    1 
ATOM   8049  O  O    . VAL E 1 260 ? 60.663  -61.678 28.593  1.00 58.56  ? 467 VAL E O    1 
ATOM   8050  C  CB   . VAL E 1 260 ? 62.501  -60.633 30.954  1.00 62.96  ? 467 VAL E CB   1 
ATOM   8051  C  CG1  . VAL E 1 260 ? 61.120  -60.119 31.316  1.00 50.62  ? 467 VAL E CG1  1 
ATOM   8052  C  CG2  . VAL E 1 260 ? 62.845  -61.889 31.731  1.00 52.42  ? 467 VAL E CG2  1 
ATOM   8053  N  N    . TYR E 1 261 ? 62.431  -63.081 28.611  1.00 63.74  ? 468 TYR E N    1 
ATOM   8054  C  CA   . TYR E 1 261 ? 61.646  -64.248 28.156  1.00 62.70  ? 468 TYR E CA   1 
ATOM   8055  C  C    . TYR E 1 261 ? 61.446  -65.141 29.374  1.00 64.66  ? 468 TYR E C    1 
ATOM   8056  O  O    . TYR E 1 261 ? 62.417  -65.360 30.095  1.00 69.35  ? 468 TYR E O    1 
ATOM   8057  C  CB   . TYR E 1 261 ? 62.389  -64.979 27.041  1.00 62.75  ? 468 TYR E CB   1 
ATOM   8058  C  CG   . TYR E 1 261 ? 62.495  -64.213 25.749  1.00 66.61  ? 468 TYR E CG   1 
ATOM   8059  C  CD1  . TYR E 1 261 ? 63.510  -63.296 25.542  1.00 68.08  ? 468 TYR E CD1  1 
ATOM   8060  C  CD2  . TYR E 1 261 ? 61.579  -64.403 24.730  1.00 68.15  ? 468 TYR E CD2  1 
ATOM   8061  C  CE1  . TYR E 1 261 ? 63.613  -62.587 24.359  1.00 64.66  ? 468 TYR E CE1  1 
ATOM   8062  C  CE2  . TYR E 1 261 ? 61.672  -63.707 23.537  1.00 67.21  ? 468 TYR E CE2  1 
ATOM   8063  C  CZ   . TYR E 1 261 ? 62.691  -62.793 23.353  1.00 65.70  ? 468 TYR E CZ   1 
ATOM   8064  O  OH   . TYR E 1 261 ? 62.791  -62.096 22.187  1.00 73.30  ? 468 TYR E OH   1 
ATOM   8065  N  N    . LEU E 1 262 ? 60.234  -65.640 29.591  1.00 60.69  ? 469 LEU E N    1 
ATOM   8066  C  CA   . LEU E 1 262 ? 59.987  -66.416 30.825  1.00 61.43  ? 469 LEU E CA   1 
ATOM   8067  C  C    . LEU E 1 262 ? 58.993  -67.551 30.595  1.00 64.67  ? 469 LEU E C    1 
ATOM   8068  O  O    . LEU E 1 262 ? 58.024  -67.320 29.869  1.00 69.60  ? 469 LEU E O    1 
ATOM   8069  C  CB   . LEU E 1 262 ? 59.423  -65.451 31.867  1.00 62.49  ? 469 LEU E CB   1 
ATOM   8070  C  CG   . LEU E 1 262 ? 60.313  -65.124 33.059  1.00 61.27  ? 469 LEU E CG   1 
ATOM   8071  C  CD1  . LEU E 1 262 ? 60.073  -63.695 33.507  1.00 54.19  ? 469 LEU E CD1  1 
ATOM   8072  C  CD2  . LEU E 1 262 ? 60.045  -66.085 34.203  1.00 55.21  ? 469 LEU E CD2  1 
ATOM   8073  N  N    . ASN E 1 263 ? 59.263  -68.742 31.133  1.00 61.15  ? 470 ASN E N    1 
ATOM   8074  C  CA   . ASN E 1 263 ? 58.253  -69.836 31.150  1.00 65.90  ? 470 ASN E CA   1 
ATOM   8075  C  C    . ASN E 1 263 ? 57.769  -69.826 32.603  1.00 66.11  ? 470 ASN E C    1 
ATOM   8076  O  O    . ASN E 1 263 ? 58.257  -70.626 33.399  1.00 64.01  ? 470 ASN E O    1 
ATOM   8077  C  CB   . ASN E 1 263 ? 58.757  -71.156 30.543  1.00 65.99  ? 470 ASN E CB   1 
ATOM   8078  C  CG   . ASN E 1 263 ? 59.790  -71.939 31.325  1.00 70.68  ? 470 ASN E CG   1 
ATOM   8079  O  OD1  . ASN E 1 263 ? 59.687  -73.155 31.434  1.00 72.03  ? 470 ASN E OD1  1 
ATOM   8080  N  ND2  . ASN E 1 263 ? 60.792  -71.267 31.859  1.00 64.97  ? 470 ASN E ND2  1 
ATOM   8081  N  N    . PRO E 1 264 ? 56.828  -68.943 32.993  1.00 61.91  ? 471 PRO E N    1 
ATOM   8082  C  CA   . PRO E 1 264 ? 56.476  -68.754 34.413  1.00 62.87  ? 471 PRO E CA   1 
ATOM   8083  C  C    . PRO E 1 264 ? 56.177  -69.978 35.287  1.00 65.30  ? 471 PRO E C    1 
ATOM   8084  O  O    . PRO E 1 264 ? 56.339  -69.865 36.476  1.00 70.72  ? 471 PRO E O    1 
ATOM   8085  C  CB   . PRO E 1 264 ? 55.220  -67.882 34.308  1.00 62.34  ? 471 PRO E CB   1 
ATOM   8086  C  CG   . PRO E 1 264 ? 55.459  -67.086 33.061  1.00 61.73  ? 471 PRO E CG   1 
ATOM   8087  C  CD   . PRO E 1 264 ? 55.975  -68.142 32.114  1.00 60.38  ? 471 PRO E CD   1 
ATOM   8088  N  N    . LYS E 1 265 ? 55.757  -71.089 34.694  1.00 68.26  ? 472 LYS E N    1 
ATOM   8089  C  CA   . LYS E 1 265 ? 55.361  -72.273 35.493  1.00 67.90  ? 472 LYS E CA   1 
ATOM   8090  C  C    . LYS E 1 265 ? 56.438  -73.354 35.412  1.00 63.87  ? 472 LYS E C    1 
ATOM   8091  O  O    . LYS E 1 265 ? 56.330  -74.333 36.158  1.00 60.71  ? 472 LYS E O    1 
ATOM   8092  C  CB   . LYS E 1 265 ? 54.012  -72.785 34.992  1.00 57.71  ? 472 LYS E CB   1 
ATOM   8093  N  N    . GLY E 1 266 ? 57.446  -73.169 34.566  1.00 56.06  ? 473 GLY E N    1 
ATOM   8094  C  CA   . GLY E 1 266 ? 58.509  -74.151 34.526  1.00 61.78  ? 473 GLY E CA   1 
ATOM   8095  C  C    . GLY E 1 266 ? 58.264  -75.295 33.577  1.00 66.99  ? 473 GLY E C    1 
ATOM   8096  O  O    . GLY E 1 266 ? 58.858  -76.364 33.754  1.00 68.34  ? 473 GLY E O    1 
ATOM   8097  N  N    . ASP E 1 267 ? 57.423  -75.092 32.558  1.00 69.51  ? 474 ASP E N    1 
ATOM   8098  C  CA   . ASP E 1 267 ? 56.867  -76.160 31.744  1.00 63.86  ? 474 ASP E CA   1 
ATOM   8099  C  C    . ASP E 1 267 ? 57.305  -76.132 30.283  1.00 72.11  ? 474 ASP E C    1 
ATOM   8100  O  O    . ASP E 1 267 ? 57.024  -77.087 29.552  1.00 76.11  ? 474 ASP E O    1 
ATOM   8101  C  CB   . ASP E 1 267 ? 55.337  -76.089 31.797  1.00 62.16  ? 474 ASP E CB   1 
ATOM   8102  C  CG   . ASP E 1 267 ? 54.805  -74.745 31.327  1.00 70.67  ? 474 ASP E CG   1 
ATOM   8103  O  OD1  . ASP E 1 267 ? 55.569  -73.997 30.671  1.00 66.89  ? 474 ASP E OD1  1 
ATOM   8104  O  OD2  . ASP E 1 267 ? 53.627  -74.423 31.622  1.00 70.39  ? 474 ASP E OD2  1 
ATOM   8105  N  N    . GLY E 1 268 ? 57.951  -75.064 29.829  1.00 70.93  ? 475 GLY E N    1 
ATOM   8106  C  CA   . GLY E 1 268 ? 58.245  -74.885 28.424  1.00 72.62  ? 475 GLY E CA   1 
ATOM   8107  C  C    . GLY E 1 268 ? 57.365  -73.876 27.707  1.00 68.04  ? 475 GLY E C    1 
ATOM   8108  O  O    . GLY E 1 268 ? 57.672  -73.526 26.563  1.00 67.42  ? 475 GLY E O    1 
ATOM   8109  N  N    . LYS E 1 269 ? 56.296  -73.387 28.345  1.00 64.33  ? 476 LYS E N    1 
ATOM   8110  C  CA   . LYS E 1 269 ? 55.319  -72.500 27.706  1.00 63.06  ? 476 LYS E CA   1 
ATOM   8111  C  C    . LYS E 1 269 ? 55.810  -71.060 27.830  1.00 65.46  ? 476 LYS E C    1 
ATOM   8112  O  O    . LYS E 1 269 ? 55.471  -70.343 28.775  1.00 65.94  ? 476 LYS E O    1 
ATOM   8113  C  CB   . LYS E 1 269 ? 53.944  -72.694 28.335  1.00 58.73  ? 476 LYS E CB   1 
ATOM   8114  N  N    . TRP E 1 270 ? 56.582  -70.622 26.828  1.00 70.91  ? 477 TRP E N    1 
ATOM   8115  C  CA   . TRP E 1 270 ? 57.440  -69.439 26.909  1.00 64.99  ? 477 TRP E CA   1 
ATOM   8116  C  C    . TRP E 1 270 ? 56.726  -68.167 26.466  1.00 68.03  ? 477 TRP E C    1 
ATOM   8117  O  O    . TRP E 1 270 ? 55.973  -68.177 25.488  1.00 74.00  ? 477 TRP E O    1 
ATOM   8118  C  CB   . TRP E 1 270 ? 58.684  -69.644 26.041  1.00 62.12  ? 477 TRP E CB   1 
ATOM   8119  C  CG   . TRP E 1 270 ? 59.742  -70.462 26.715  1.00 67.90  ? 477 TRP E CG   1 
ATOM   8120  C  CD1  . TRP E 1 270 ? 59.971  -71.796 26.558  1.00 70.70  ? 477 TRP E CD1  1 
ATOM   8121  C  CD2  . TRP E 1 270 ? 60.711  -69.996 27.667  1.00 65.96  ? 477 TRP E CD2  1 
ATOM   8122  N  NE1  . TRP E 1 270 ? 61.018  -72.192 27.355  1.00 73.35  ? 477 TRP E NE1  1 
ATOM   8123  C  CE2  . TRP E 1 270 ? 61.490  -71.104 28.044  1.00 68.53  ? 477 TRP E CE2  1 
ATOM   8124  C  CE3  . TRP E 1 270 ? 60.998  -68.747 28.230  1.00 66.56  ? 477 TRP E CE3  1 
ATOM   8125  C  CZ2  . TRP E 1 270 ? 62.541  -71.002 28.956  1.00 69.67  ? 477 TRP E CZ2  1 
ATOM   8126  C  CZ3  . TRP E 1 270 ? 62.035  -68.648 29.147  1.00 68.31  ? 477 TRP E CZ3  1 
ATOM   8127  C  CH2  . TRP E 1 270 ? 62.795  -69.771 29.500  1.00 69.26  ? 477 TRP E CH2  1 
ATOM   8128  N  N    . CYS E 1 271 ? 56.995  -67.061 27.170  1.00 65.95  ? 478 CYS E N    1 
ATOM   8129  C  CA   . CYS E 1 271 ? 56.408  -65.758 26.858  1.00 71.27  ? 478 CYS E CA   1 
ATOM   8130  C  C    . CYS E 1 271 ? 57.455  -64.643 26.885  1.00 71.85  ? 478 CYS E C    1 
ATOM   8131  O  O    . CYS E 1 271 ? 58.290  -64.582 27.795  1.00 66.44  ? 478 CYS E O    1 
ATOM   8132  C  CB   . CYS E 1 271 ? 55.281  -65.400 27.840  1.00 68.83  ? 478 CYS E CB   1 
ATOM   8133  S  SG   . CYS E 1 271 ? 53.751  -66.350 27.643  1.00 79.00  ? 478 CYS E SG   1 
ATOM   8134  N  N    . LYS E 1 272 ? 57.379  -63.742 25.895  1.00 69.93  ? 479 LYS E N    1 
ATOM   8135  C  CA   . LYS E 1 272 ? 58.217  -62.548 25.829  1.00 62.61  ? 479 LYS E CA   1 
ATOM   8136  C  C    . LYS E 1 272 ? 57.537  -61.399 26.552  1.00 67.59  ? 479 LYS E C    1 
ATOM   8137  O  O    . LYS E 1 272 ? 56.359  -61.117 26.309  1.00 78.00  ? 479 LYS E O    1 
ATOM   8138  C  CB   . LYS E 1 272 ? 58.491  -62.140 24.379  1.00 66.01  ? 479 LYS E CB   1 
ATOM   8139  N  N    . PHE E 1 273 ? 58.296  -60.741 27.426  1.00 67.81  ? 480 PHE E N    1 
ATOM   8140  C  CA   . PHE E 1 273 ? 57.771  -59.599 28.211  1.00 65.89  ? 480 PHE E CA   1 
ATOM   8141  C  C    . PHE E 1 273 ? 58.556  -58.353 27.806  1.00 69.06  ? 480 PHE E C    1 
ATOM   8142  O  O    . PHE E 1 273 ? 59.700  -58.207 28.260  1.00 69.98  ? 480 PHE E O    1 
ATOM   8143  C  CB   . PHE E 1 273 ? 57.871  -59.884 29.709  1.00 63.78  ? 480 PHE E CB   1 
ATOM   8144  C  CG   . PHE E 1 273 ? 57.014  -61.001 30.245  1.00 66.19  ? 480 PHE E CG   1 
ATOM   8145  C  CD1  . PHE E 1 273 ? 57.358  -62.326 30.043  1.00 64.03  ? 480 PHE E CD1  1 
ATOM   8146  C  CD2  . PHE E 1 273 ? 55.884  -60.724 30.992  1.00 65.22  ? 480 PHE E CD2  1 
ATOM   8147  C  CE1  . PHE E 1 273 ? 56.571  -63.348 30.544  1.00 64.83  ? 480 PHE E CE1  1 
ATOM   8148  C  CE2  . PHE E 1 273 ? 55.099  -61.746 31.494  1.00 65.69  ? 480 PHE E CE2  1 
ATOM   8149  C  CZ   . PHE E 1 273 ? 55.440  -63.056 31.263  1.00 60.08  ? 480 PHE E CZ   1 
ATOM   8150  N  N    . ASP E 1 274 ? 57.963  -57.492 26.985  1.00 69.67  ? 481 ASP E N    1 
ATOM   8151  C  CA   . ASP E 1 274 ? 58.596  -56.278 26.460  1.00 66.60  ? 481 ASP E CA   1 
ATOM   8152  C  C    . ASP E 1 274 ? 57.769  -55.100 26.944  1.00 71.81  ? 481 ASP E C    1 
ATOM   8153  O  O    . ASP E 1 274 ? 56.905  -54.598 26.224  1.00 75.59  ? 481 ASP E O    1 
ATOM   8154  C  CB   . ASP E 1 274 ? 58.710  -56.297 24.887  1.00 68.78  ? 481 ASP E CB   1 
ATOM   8155  C  CG   . ASP E 1 274 ? 59.659  -55.229 24.346  1.00 68.47  ? 481 ASP E CG   1 
ATOM   8156  O  OD1  . ASP E 1 274 ? 59.909  -54.230 25.052  1.00 65.26  ? 481 ASP E OD1  1 
ATOM   8157  O  OD2  . ASP E 1 274 ? 60.154  -55.382 23.206  1.00 71.41  ? 481 ASP E OD2  1 
ATOM   8158  N  N    . ASP E 1 275 ? 58.052  -54.658 28.166  1.00 68.38  ? 482 ASP E N    1 
ATOM   8159  C  CA   . ASP E 1 275 ? 57.346  -53.551 28.796  1.00 66.61  ? 482 ASP E CA   1 
ATOM   8160  C  C    . ASP E 1 275 ? 55.849  -53.809 28.765  1.00 65.67  ? 482 ASP E C    1 
ATOM   8161  O  O    . ASP E 1 275 ? 55.385  -54.766 29.387  1.00 72.41  ? 482 ASP E O    1 
ATOM   8162  C  CB   . ASP E 1 275 ? 57.705  -52.217 28.131  1.00 65.28  ? 482 ASP E CB   1 
ATOM   8163  C  CG   . ASP E 1 275 ? 59.067  -51.690 28.585  1.00 68.02  ? 482 ASP E CG   1 
ATOM   8164  O  OD1  . ASP E 1 275 ? 59.535  -52.118 29.665  1.00 66.24  ? 482 ASP E OD1  1 
ATOM   8165  O  OD2  . ASP E 1 275 ? 59.678  -50.860 27.871  1.00 62.15  ? 482 ASP E OD2  1 
ATOM   8166  N  N    . ASP E 1 276 ? 55.092  -52.964 28.054  1.00 68.01  ? 483 ASP E N    1 
ATOM   8167  C  CA   . ASP E 1 276 ? 53.628  -53.014 28.103  1.00 71.75  ? 483 ASP E CA   1 
ATOM   8168  C  C    . ASP E 1 276 ? 53.051  -54.204 27.332  1.00 70.08  ? 483 ASP E C    1 
ATOM   8169  O  O    . ASP E 1 276 ? 51.977  -54.701 27.685  1.00 68.20  ? 483 ASP E O    1 
ATOM   8170  C  CB   . ASP E 1 276 ? 53.054  -51.724 27.540  1.00 69.19  ? 483 ASP E CB   1 
ATOM   8171  C  CG   . ASP E 1 276 ? 53.378  -51.563 26.072  1.00 73.59  ? 483 ASP E CG   1 
ATOM   8172  O  OD1  . ASP E 1 276 ? 54.509  -51.146 25.746  1.00 72.64  ? 483 ASP E OD1  1 
ATOM   8173  O  OD2  . ASP E 1 276 ? 52.513  -51.900 25.239  1.00 76.64  ? 483 ASP E OD2  1 
ATOM   8174  N  N    . VAL E 1 277 ? 53.721  -54.664 26.281  1.00 68.51  ? 484 VAL E N    1 
ATOM   8175  C  CA   . VAL E 1 277 ? 53.245  -55.800 25.501  1.00 74.16  ? 484 VAL E CA   1 
ATOM   8176  C  C    . VAL E 1 277 ? 53.857  -57.081 26.048  1.00 72.02  ? 484 VAL E C    1 
ATOM   8177  O  O    . VAL E 1 277 ? 55.065  -57.144 26.303  1.00 71.58  ? 484 VAL E O    1 
ATOM   8178  C  CB   . VAL E 1 277 ? 53.576  -55.632 24.007  1.00 73.58  ? 484 VAL E CB   1 
ATOM   8179  C  CG1  . VAL E 1 277 ? 55.040  -55.289 23.807  1.00 76.65  ? 484 VAL E CG1  1 
ATOM   8180  C  CG2  . VAL E 1 277 ? 53.238  -56.911 23.254  1.00 70.29  ? 484 VAL E CG2  1 
ATOM   8181  N  N    . VAL E 1 278 ? 53.020  -58.100 26.232  1.00 71.27  ? 485 VAL E N    1 
ATOM   8182  C  CA   . VAL E 1 278 ? 53.453  -59.446 26.586  1.00 70.08  ? 485 VAL E CA   1 
ATOM   8183  C  C    . VAL E 1 278 ? 52.968  -60.401 25.504  1.00 73.14  ? 485 VAL E C    1 
ATOM   8184  O  O    . VAL E 1 278 ? 51.774  -60.427 25.182  1.00 73.21  ? 485 VAL E O    1 
ATOM   8185  C  CB   . VAL E 1 278 ? 52.912  -59.874 27.961  1.00 68.77  ? 485 VAL E CB   1 
ATOM   8186  C  CG1  . VAL E 1 278 ? 53.390  -61.280 28.298  1.00 73.87  ? 485 VAL E CG1  1 
ATOM   8187  C  CG2  . VAL E 1 278 ? 53.353  -58.896 29.025  1.00 68.12  ? 485 VAL E CG2  1 
ATOM   8188  N  N    . SER E 1 279 ? 53.885  -61.202 24.973  1.00 73.40  ? 486 SER E N    1 
ATOM   8189  C  CA   . SER E 1 279 ? 53.616  -62.085 23.849  1.00 74.93  ? 486 SER E CA   1 
ATOM   8190  C  C    . SER E 1 279 ? 54.012  -63.520 24.180  1.00 76.50  ? 486 SER E C    1 
ATOM   8191  O  O    . SER E 1 279 ? 54.991  -63.758 24.892  1.00 78.74  ? 486 SER E O    1 
ATOM   8192  C  CB   . SER E 1 279 ? 54.398  -61.633 22.614  1.00 76.59  ? 486 SER E CB   1 
ATOM   8193  O  OG   . SER E 1 279 ? 54.450  -60.217 22.559  1.00 81.85  ? 486 SER E OG   1 
ATOM   8194  N  N    . ARG E 1 280 ? 53.265  -64.478 23.634  1.00 74.26  ? 487 ARG E N    1 
ATOM   8195  C  CA   . ARG E 1 280 ? 53.697  -65.868 23.648  1.00 70.01  ? 487 ARG E CA   1 
ATOM   8196  C  C    . ARG E 1 280 ? 54.744  -66.106 22.548  1.00 72.76  ? 487 ARG E C    1 
ATOM   8197  O  O    . ARG E 1 280 ? 54.841  -65.352 21.576  1.00 71.43  ? 487 ARG E O    1 
ATOM   8198  C  CB   . ARG E 1 280 ? 52.491  -66.795 23.480  1.00 61.66  ? 487 ARG E CB   1 
ATOM   8199  N  N    . CYS E 1 281 ? 55.548  -67.159 22.710  1.00 70.40  ? 488 CYS E N    1 
ATOM   8200  C  CA   . CYS E 1 281 ? 56.688  -67.338 21.819  1.00 64.82  ? 488 CYS E CA   1 
ATOM   8201  C  C    . CYS E 1 281 ? 57.146  -68.791 21.819  1.00 71.22  ? 488 CYS E C    1 
ATOM   8202  O  O    . CYS E 1 281 ? 56.753  -69.596 22.669  1.00 67.57  ? 488 CYS E O    1 
ATOM   8203  C  CB   . CYS E 1 281 ? 57.849  -66.431 22.222  1.00 76.21  ? 488 CYS E CB   1 
ATOM   8204  S  SG   . CYS E 1 281 ? 58.636  -66.862 23.823  1.00 80.34  ? 488 CYS E SG   1 
ATOM   8205  N  N    . THR E 1 282 ? 58.003  -69.106 20.842  1.00 75.61  ? 489 THR E N    1 
ATOM   8206  C  CA   . THR E 1 282 ? 58.573  -70.436 20.683  1.00 74.11  ? 489 THR E CA   1 
ATOM   8207  C  C    . THR E 1 282 ? 59.718  -70.637 21.665  1.00 75.74  ? 489 THR E C    1 
ATOM   8208  O  O    . THR E 1 282 ? 60.310  -69.679 22.175  1.00 72.47  ? 489 THR E O    1 
ATOM   8209  C  CB   . THR E 1 282 ? 59.117  -70.663 19.268  1.00 68.65  ? 489 THR E CB   1 
ATOM   8210  O  OG1  . THR E 1 282 ? 59.958  -69.570 18.899  1.00 71.38  ? 489 THR E OG1  1 
ATOM   8211  C  CG2  . THR E 1 282 ? 58.003  -70.777 18.257  1.00 75.89  ? 489 THR E CG2  1 
ATOM   8212  N  N    . LYS E 1 283 ? 60.047  -71.908 21.906  1.00 71.45  ? 490 LYS E N    1 
ATOM   8213  C  CA   . LYS E 1 283 ? 61.243  -72.201 22.683  1.00 72.16  ? 490 LYS E CA   1 
ATOM   8214  C  C    . LYS E 1 283 ? 62.494  -71.733 21.946  1.00 76.41  ? 490 LYS E C    1 
ATOM   8215  O  O    . LYS E 1 283 ? 63.446  -71.253 22.577  1.00 74.81  ? 490 LYS E O    1 
ATOM   8216  C  CB   . LYS E 1 283 ? 61.322  -73.692 23.006  1.00 67.07  ? 490 LYS E CB   1 
ATOM   8217  N  N    . GLU E 1 284 ? 62.502  -71.839 20.608  1.00 76.44  ? 491 GLU E N    1 
ATOM   8218  C  CA   . GLU E 1 284 ? 63.651  -71.377 19.832  1.00 72.22  ? 491 GLU E CA   1 
ATOM   8219  C  C    . GLU E 1 284 ? 63.833  -69.867 19.955  1.00 75.26  ? 491 GLU E C    1 
ATOM   8220  O  O    . GLU E 1 284 ? 64.963  -69.377 20.087  1.00 72.78  ? 491 GLU E O    1 
ATOM   8221  N  N    . GLU E 1 285 ? 62.738  -69.109 19.970  1.00 78.69  ? 492 GLU E N    1 
ATOM   8222  C  CA   . GLU E 1 285 ? 62.831  -67.623 20.024  1.00 76.47  ? 492 GLU E CA   1 
ATOM   8223  C  C    . GLU E 1 285 ? 63.301  -67.149 21.402  1.00 72.26  ? 492 GLU E C    1 
ATOM   8224  O  O    . GLU E 1 285 ? 63.846  -66.044 21.480  1.00 70.20  ? 492 GLU E O    1 
ATOM   8225  C  CB   . GLU E 1 285 ? 61.485  -66.979 19.703  1.00 70.53  ? 492 GLU E CB   1 
ATOM   8226  C  CG   . GLU E 1 285 ? 61.299  -66.637 18.238  1.00 75.74  ? 492 GLU E CG   1 
ATOM   8227  C  CD   . GLU E 1 285 ? 59.854  -66.609 17.769  1.00 80.55  ? 492 GLU E CD   1 
ATOM   8228  O  OE1  . GLU E 1 285 ? 58.957  -66.886 18.589  1.00 78.75  ? 492 GLU E OE1  1 
ATOM   8229  O  OE2  . GLU E 1 285 ? 59.629  -66.317 16.582  1.00 76.06  ? 492 GLU E OE2  1 
ATOM   8230  N  N    . ALA E 1 286 ? 63.097  -67.952 22.440  1.00 74.30  ? 493 ALA E N    1 
ATOM   8231  C  CA   . ALA E 1 286 ? 63.448  -67.541 23.816  1.00 67.60  ? 493 ALA E CA   1 
ATOM   8232  C  C    . ALA E 1 286 ? 64.851  -68.007 24.193  1.00 66.69  ? 493 ALA E C    1 
ATOM   8233  O  O    . ALA E 1 286 ? 65.500  -67.322 24.988  1.00 62.79  ? 493 ALA E O    1 
ATOM   8234  C  CB   . ALA E 1 286 ? 62.438  -68.135 24.750  1.00 66.00  ? 493 ALA E CB   1 
ATOM   8235  N  N    . ILE E 1 287 ? 65.293  -69.130 23.639  1.00 71.35  ? 494 ILE E N    1 
ATOM   8236  C  CA   . ILE E 1 287 ? 66.596  -69.714 24.053  1.00 68.92  ? 494 ILE E CA   1 
ATOM   8237  C  C    . ILE E 1 287 ? 67.613  -69.570 22.926  1.00 71.30  ? 494 ILE E C    1 
ATOM   8238  O  O    . ILE E 1 287 ? 68.425  -68.642 23.000  1.00 70.03  ? 494 ILE E O    1 
ATOM   8239  C  CB   . ILE E 1 287 ? 66.384  -71.184 24.458  1.00 63.74  ? 494 ILE E CB   1 
ATOM   8240  C  CG1  . ILE E 1 287 ? 65.283  -71.328 25.512  1.00 65.21  ? 494 ILE E CG1  1 
ATOM   8241  C  CG2  . ILE E 1 287 ? 67.679  -71.827 24.925  1.00 66.63  ? 494 ILE E CG2  1 
ATOM   8242  C  CD1  . ILE E 1 287 ? 64.876  -72.753 25.779  1.00 62.61  ? 494 ILE E CD1  1 
ATOM   8243  N  N    . GLU E 1 288 ? 67.539  -70.421 21.907  1.00 72.41  ? 495 GLU E N    1 
ATOM   8244  C  CA   . GLU E 1 288 ? 68.564  -70.449 20.832  1.00 73.47  ? 495 GLU E CA   1 
ATOM   8245  C  C    . GLU E 1 288 ? 68.700  -69.093 20.122  1.00 75.12  ? 495 GLU E C    1 
ATOM   8246  O  O    . GLU E 1 288 ? 69.808  -68.795 19.667  1.00 69.51  ? 495 GLU E O    1 
ATOM   8247  C  CB   . GLU E 1 288 ? 68.250  -71.600 19.874  1.00 73.88  ? 495 GLU E CB   1 
ATOM   8248  C  CG   . GLU E 1 288 ? 68.499  -72.973 20.470  1.00 71.24  ? 495 GLU E CG   1 
ATOM   8249  C  CD   . GLU E 1 288 ? 67.314  -73.646 21.141  1.00 75.36  ? 495 GLU E CD   1 
ATOM   8250  O  OE1  . GLU E 1 288 ? 66.244  -73.019 21.227  1.00 71.88  ? 495 GLU E OE1  1 
ATOM   8251  O  OE2  . GLU E 1 288 ? 67.467  -74.799 21.583  1.00 75.77  ? 495 GLU E OE2  1 
ATOM   8252  N  N    . HIS E 1 289 ? 67.632  -68.308 20.036  1.00 70.39  ? 496 HIS E N    1 
ATOM   8253  C  CA   . HIS E 1 289 ? 67.709  -67.038 19.273  1.00 73.07  ? 496 HIS E CA   1 
ATOM   8254  C  C    . HIS E 1 289 ? 68.472  -65.973 20.067  1.00 72.92  ? 496 HIS E C    1 
ATOM   8255  O  O    . HIS E 1 289 ? 69.004  -65.047 19.442  1.00 74.34  ? 496 HIS E O    1 
ATOM   8256  C  CB   . HIS E 1 289 ? 66.306  -66.581 18.875  1.00 78.66  ? 496 HIS E CB   1 
ATOM   8257  C  CG   . HIS E 1 289 ? 65.788  -67.231 17.638  1.00 80.82  ? 496 HIS E CG   1 
ATOM   8258  N  ND1  . HIS E 1 289 ? 64.812  -66.650 16.859  1.00 81.34  ? 496 HIS E ND1  1 
ATOM   8259  C  CD2  . HIS E 1 289 ? 66.099  -68.403 17.046  1.00 82.72  ? 496 HIS E CD2  1 
ATOM   8260  C  CE1  . HIS E 1 289 ? 64.544  -67.436 15.838  1.00 80.56  ? 496 HIS E CE1  1 
ATOM   8261  N  NE2  . HIS E 1 289 ? 65.321  -68.517 15.930  1.00 81.86  ? 496 HIS E NE2  1 
ATOM   8262  N  N    . ASN E 1 290 ? 68.523  -66.110 21.388  1.00 73.91  ? 497 ASN E N    1 
ATOM   8263  C  CA   . ASN E 1 290 ? 69.239  -65.143 22.253  1.00 66.53  ? 497 ASN E CA   1 
ATOM   8264  C  C    . ASN E 1 290 ? 70.633  -65.690 22.563  1.00 67.17  ? 497 ASN E C    1 
ATOM   8265  O  O    . ASN E 1 290 ? 71.235  -65.241 23.541  1.00 65.81  ? 497 ASN E O    1 
ATOM   8266  C  CB   . ASN E 1 290 ? 68.404  -64.837 23.494  1.00 68.33  ? 497 ASN E CB   1 
ATOM   8267  C  CG   . ASN E 1 290 ? 67.044  -64.273 23.154  1.00 70.43  ? 497 ASN E CG   1 
ATOM   8268  O  OD1  . ASN E 1 290 ? 66.938  -63.271 22.454  1.00 71.71  ? 497 ASN E OD1  1 
ATOM   8269  N  ND2  . ASN E 1 290 ? 65.999  -64.909 23.648  1.00 67.49  ? 497 ASN E ND2  1 
ATOM   8270  N  N    . TYR E 1 291 ? 71.121  -66.627 21.754  1.00 67.16  ? 498 TYR E N    1 
ATOM   8271  C  CA   . TYR E 1 291 ? 72.501  -67.141 21.926  1.00 68.16  ? 498 TYR E CA   1 
ATOM   8272  C  C    . TYR E 1 291 ? 73.485  -66.095 21.406  1.00 64.67  ? 498 TYR E C    1 
ATOM   8273  O  O    . TYR E 1 291 ? 74.631  -66.108 21.847  1.00 66.45  ? 498 TYR E O    1 
ATOM   8274  C  CB   . TYR E 1 291 ? 72.708  -68.441 21.153  1.00 69.87  ? 498 TYR E CB   1 
ATOM   8275  C  CG   . TYR E 1 291 ? 72.181  -69.707 21.775  1.00 71.30  ? 498 TYR E CG   1 
ATOM   8276  C  CD1  . TYR E 1 291 ? 71.504  -69.705 22.979  1.00 72.07  ? 498 TYR E CD1  1 
ATOM   8277  C  CD2  . TYR E 1 291 ? 72.360  -70.922 21.140  1.00 70.84  ? 498 TYR E CD2  1 
ATOM   8278  C  CE1  . TYR E 1 291 ? 71.019  -70.875 23.537  1.00 72.95  ? 498 TYR E CE1  1 
ATOM   8279  C  CE2  . TYR E 1 291 ? 71.886  -72.103 21.684  1.00 69.98  ? 498 TYR E CE2  1 
ATOM   8280  C  CZ   . TYR E 1 291 ? 71.215  -72.080 22.890  1.00 75.31  ? 498 TYR E CZ   1 
ATOM   8281  O  OH   . TYR E 1 291 ? 70.747  -73.241 23.430  1.00 65.71  ? 498 TYR E OH   1 
ATOM   8282  N  N    . GLY E 1 292 ? 73.049  -65.236 20.482  1.00 67.50  ? 499 GLY E N    1 
ATOM   8283  C  CA   . GLY E 1 292 ? 73.903  -64.178 19.981  1.00 71.79  ? 499 GLY E CA   1 
ATOM   8284  C  C    . GLY E 1 292 ? 74.840  -64.630 18.868  1.00 70.39  ? 499 GLY E C    1 
ATOM   8285  O  O    . GLY E 1 292 ? 75.080  -65.817 18.648  1.00 65.80  ? 499 GLY E O    1 
ATOM   8286  N  N    . GLY E 1 293 ? 75.383  -63.647 18.156  1.00 70.87  ? 500 GLY E N    1 
ATOM   8287  C  CA   . GLY E 1 293 ? 76.353  -63.910 17.103  1.00 74.62  ? 500 GLY E CA   1 
ATOM   8288  C  C    . GLY E 1 293 ? 75.787  -63.761 15.704  1.00 79.19  ? 500 GLY E C    1 
ATOM   8289  O  O    . GLY E 1 293 ? 74.577  -63.920 15.488  1.00 78.91  ? 500 GLY E O    1 
ATOM   8290  N  N    . ARG E 1 301 ? 69.621  -57.539 15.845  1.00 93.00  ? 508 ARG E N    1 
ATOM   8291  C  CA   . ARG E 1 301 ? 69.577  -59.017 15.986  1.00 93.60  ? 508 ARG E CA   1 
ATOM   8292  C  C    . ARG E 1 301 ? 70.951  -59.510 16.438  1.00 98.35  ? 508 ARG E C    1 
ATOM   8293  O  O    . ARG E 1 301 ? 71.011  -60.260 17.425  1.00 93.34  ? 508 ARG E O    1 
ATOM   8294  C  CB   . ARG E 1 301 ? 69.176  -59.671 14.663  1.00 87.64  ? 508 ARG E CB   1 
ATOM   8295  N  N    . HIS E 1 302 ? 72.007  -59.140 15.714  1.00 100.06 ? 509 HIS E N    1 
ATOM   8296  C  CA   . HIS E 1 302 ? 73.366  -59.496 16.122  1.00 95.85  ? 509 HIS E CA   1 
ATOM   8297  C  C    . HIS E 1 302 ? 73.685  -58.940 17.506  1.00 92.43  ? 509 HIS E C    1 
ATOM   8298  O  O    . HIS E 1 302 ? 74.222  -59.657 18.364  1.00 82.59  ? 509 HIS E O    1 
ATOM   8299  C  CB   . HIS E 1 302 ? 74.376  -58.995 15.085  1.00 91.28  ? 509 HIS E CB   1 
ATOM   8300  N  N    . CYS E 1 303 ? 73.241  -57.709 17.760  1.00 91.40  ? 510 CYS E N    1 
ATOM   8301  C  CA   . CYS E 1 303 ? 73.488  -57.046 19.065  1.00 83.89  ? 510 CYS E CA   1 
ATOM   8302  C  C    . CYS E 1 303 ? 72.503  -57.524 20.141  1.00 82.76  ? 510 CYS E C    1 
ATOM   8303  O  O    . CYS E 1 303 ? 72.580  -56.991 21.257  1.00 82.60  ? 510 CYS E O    1 
ATOM   8304  C  CB   . CYS E 1 303 ? 73.334  -55.544 18.882  1.00 83.76  ? 510 CYS E CB   1 
ATOM   8305  S  SG   . CYS E 1 303 ? 71.904  -55.095 17.866  1.00 104.79 ? 510 CYS E SG   1 
ATOM   8306  N  N    . THR E 1 304 ? 71.629  -58.487 19.835  1.00 78.70  ? 511 THR E N    1 
ATOM   8307  C  CA   . THR E 1 304 ? 70.587  -58.937 20.798  1.00 74.99  ? 511 THR E CA   1 
ATOM   8308  C  C    . THR E 1 304 ? 70.968  -60.314 21.347  1.00 78.78  ? 511 THR E C    1 
ATOM   8309  O  O    . THR E 1 304 ? 71.151  -61.226 20.522  1.00 80.59  ? 511 THR E O    1 
ATOM   8310  C  CB   . THR E 1 304 ? 69.205  -58.911 20.139  1.00 72.18  ? 511 THR E CB   1 
ATOM   8311  O  OG1  . THR E 1 304 ? 69.014  -57.633 19.533  1.00 75.87  ? 511 THR E OG1  1 
ATOM   8312  C  CG2  . THR E 1 304 ? 68.073  -59.178 21.102  1.00 69.57  ? 511 THR E CG2  1 
ATOM   8313  N  N    . ASN E 1 305 ? 71.051  -60.468 22.676  1.00 75.72  ? 512 ASN E N    1 
ATOM   8314  C  CA   . ASN E 1 305 ? 71.519  -61.715 23.273  1.00 71.71  ? 512 ASN E CA   1 
ATOM   8315  C  C    . ASN E 1 305 ? 71.246  -61.688 24.771  1.00 64.58  ? 512 ASN E C    1 
ATOM   8316  O  O    . ASN E 1 305 ? 70.961  -60.642 25.358  1.00 63.19  ? 512 ASN E O    1 
ATOM   8317  C  CB   . ASN E 1 305 ? 73.010  -61.945 23.001  1.00 67.90  ? 512 ASN E CB   1 
ATOM   8318  C  CG   . ASN E 1 305 ? 73.823  -60.671 23.100  1.00 67.09  ? 512 ASN E CG   1 
ATOM   8319  O  OD1  . ASN E 1 305 ? 73.726  -59.936 24.080  1.00 67.86  ? 512 ASN E OD1  1 
ATOM   8320  N  ND2  . ASN E 1 305 ? 74.627  -60.398 22.076  1.00 69.34  ? 512 ASN E ND2  1 
ATOM   8321  N  N    . ALA E 1 306 ? 71.348  -62.865 25.376  1.00 63.81  ? 513 ALA E N    1 
ATOM   8322  C  CA   . ALA E 1 306 ? 71.065  -63.039 26.791  1.00 63.56  ? 513 ALA E CA   1 
ATOM   8323  C  C    . ALA E 1 306 ? 72.152  -62.386 27.626  1.00 56.83  ? 513 ALA E C    1 
ATOM   8324  O  O    . ALA E 1 306 ? 73.337  -62.524 27.327  1.00 61.03  ? 513 ALA E O    1 
ATOM   8325  C  CB   . ALA E 1 306 ? 70.984  -64.532 27.132  1.00 62.25  ? 513 ALA E CB   1 
ATOM   8326  N  N    . TYR E 1 307 ? 71.741  -61.672 28.678  1.00 54.77  ? 514 TYR E N    1 
ATOM   8327  C  CA   . TYR E 1 307 ? 72.651  -61.067 29.647  1.00 54.21  ? 514 TYR E CA   1 
ATOM   8328  C  C    . TYR E 1 307 ? 72.588  -61.749 31.006  1.00 51.88  ? 514 TYR E C    1 
ATOM   8329  O  O    . TYR E 1 307 ? 73.630  -62.091 31.570  1.00 51.85  ? 514 TYR E O    1 
ATOM   8330  C  CB   . TYR E 1 307 ? 72.333  -59.577 29.815  1.00 57.05  ? 514 TYR E CB   1 
ATOM   8331  C  CG   . TYR E 1 307 ? 73.260  -58.860 30.769  1.00 58.46  ? 514 TYR E CG   1 
ATOM   8332  C  CD1  . TYR E 1 307 ? 74.618  -59.122 30.762  1.00 53.69  ? 514 TYR E CD1  1 
ATOM   8333  C  CD2  . TYR E 1 307 ? 72.774  -57.918 31.677  1.00 60.54  ? 514 TYR E CD2  1 
ATOM   8334  C  CE1  . TYR E 1 307 ? 75.478  -58.466 31.613  1.00 54.18  ? 514 TYR E CE1  1 
ATOM   8335  C  CE2  . TYR E 1 307 ? 73.635  -57.241 32.542  1.00 55.02  ? 514 TYR E CE2  1 
ATOM   8336  C  CZ   . TYR E 1 307 ? 74.994  -57.526 32.496  1.00 55.11  ? 514 TYR E CZ   1 
ATOM   8337  O  OH   . TYR E 1 307 ? 75.888  -56.908 33.344  1.00 52.45  ? 514 TYR E OH   1 
ATOM   8338  N  N    . MET E 1 308 ? 71.385  -61.960 31.538  1.00 44.49  ? 515 MET E N    1 
ATOM   8339  C  CA   . MET E 1 308 ? 71.161  -62.652 32.803  1.00 52.09  ? 515 MET E CA   1 
ATOM   8340  C  C    . MET E 1 308 ? 70.294  -63.884 32.563  1.00 53.99  ? 515 MET E C    1 
ATOM   8341  O  O    . MET E 1 308 ? 69.272  -63.798 31.871  1.00 50.12  ? 515 MET E O    1 
ATOM   8342  C  CB   . MET E 1 308 ? 70.471  -61.722 33.813  1.00 53.08  ? 515 MET E CB   1 
ATOM   8343  C  CG   . MET E 1 308 ? 71.202  -61.542 35.129  1.00 53.39  ? 515 MET E CG   1 
ATOM   8344  S  SD   . MET E 1 308 ? 70.267  -60.559 36.328  1.00 56.84  ? 515 MET E SD   1 
ATOM   8345  C  CE   . MET E 1 308 ? 69.151  -61.777 37.049  1.00 51.40  ? 515 MET E CE   1 
ATOM   8346  N  N    . LEU E 1 309 ? 70.675  -64.997 33.185  1.00 49.16  ? 516 LEU E N    1 
ATOM   8347  C  CA   . LEU E 1 309 ? 69.911  -66.259 33.041  1.00 57.64  ? 516 LEU E CA   1 
ATOM   8348  C  C    . LEU E 1 309 ? 69.454  -66.753 34.407  1.00 57.76  ? 516 LEU E C    1 
ATOM   8349  O  O    . LEU E 1 309 ? 70.261  -66.744 35.333  1.00 57.94  ? 516 LEU E O    1 
ATOM   8350  C  CB   . LEU E 1 309 ? 70.791  -67.323 32.389  1.00 55.08  ? 516 LEU E CB   1 
ATOM   8351  C  CG   . LEU E 1 309 ? 71.275  -67.024 30.977  1.00 56.81  ? 516 LEU E CG   1 
ATOM   8352  C  CD1  . LEU E 1 309 ? 72.268  -68.080 30.538  1.00 59.44  ? 516 LEU E CD1  1 
ATOM   8353  C  CD2  . LEU E 1 309 ? 70.103  -66.969 30.022  1.00 60.11  ? 516 LEU E CD2  1 
ATOM   8354  N  N    . VAL E 1 310 ? 68.183  -67.128 34.498  1.00 57.92  ? 517 VAL E N    1 
ATOM   8355  C  CA   . VAL E 1 310 ? 67.629  -67.652 35.774  1.00 57.73  ? 517 VAL E CA   1 
ATOM   8356  C  C    . VAL E 1 310 ? 67.318  -69.134 35.605  1.00 58.07  ? 517 VAL E C    1 
ATOM   8357  O  O    . VAL E 1 310 ? 66.575  -69.475 34.691  1.00 59.66  ? 517 VAL E O    1 
ATOM   8358  C  CB   . VAL E 1 310 ? 66.396  -66.856 36.232  1.00 59.58  ? 517 VAL E CB   1 
ATOM   8359  C  CG1  . VAL E 1 310 ? 65.724  -67.480 37.443  1.00 51.44  ? 517 VAL E CG1  1 
ATOM   8360  C  CG2  . VAL E 1 310 ? 66.743  -65.403 36.499  1.00 51.87  ? 517 VAL E CG2  1 
ATOM   8361  N  N    . TYR E 1 311 ? 67.922  -69.968 36.441  1.00 55.95  ? 518 TYR E N    1 
ATOM   8362  C  CA   . TYR E 1 311 ? 67.662  -71.420 36.423  1.00 58.91  ? 518 TYR E CA   1 
ATOM   8363  C  C    . TYR E 1 311 ? 67.124  -71.807 37.797  1.00 57.25  ? 518 TYR E C    1 
ATOM   8364  O  O    . TYR E 1 311 ? 67.636  -71.314 38.792  1.00 59.99  ? 518 TYR E O    1 
ATOM   8365  C  CB   . TYR E 1 311 ? 68.952  -72.183 36.136  1.00 57.00  ? 518 TYR E CB   1 
ATOM   8366  C  CG   . TYR E 1 311 ? 69.430  -72.172 34.709  1.00 57.16  ? 518 TYR E CG   1 
ATOM   8367  C  CD1  . TYR E 1 311 ? 70.136  -71.097 34.201  1.00 55.14  ? 518 TYR E CD1  1 
ATOM   8368  C  CD2  . TYR E 1 311 ? 69.212  -73.255 33.878  1.00 60.74  ? 518 TYR E CD2  1 
ATOM   8369  C  CE1  . TYR E 1 311 ? 70.594  -71.086 32.897  1.00 56.95  ? 518 TYR E CE1  1 
ATOM   8370  C  CE2  . TYR E 1 311 ? 69.660  -73.261 32.569  1.00 58.02  ? 518 TYR E CE2  1 
ATOM   8371  C  CZ   . TYR E 1 311 ? 70.355  -72.172 32.078  1.00 62.51  ? 518 TYR E CZ   1 
ATOM   8372  O  OH   . TYR E 1 311 ? 70.803  -72.161 30.793  1.00 63.90  ? 518 TYR E OH   1 
ATOM   8373  N  N    . ILE E 1 312 ? 66.105  -72.655 37.846  1.00 58.02  ? 519 ILE E N    1 
ATOM   8374  C  CA   . ILE E 1 312 ? 65.582  -73.139 39.154  1.00 53.23  ? 519 ILE E CA   1 
ATOM   8375  C  C    . ILE E 1 312 ? 65.950  -74.612 39.323  1.00 59.42  ? 519 ILE E C    1 
ATOM   8376  O  O    . ILE E 1 312 ? 65.900  -75.345 38.339  1.00 62.09  ? 519 ILE E O    1 
ATOM   8377  C  CB   . ILE E 1 312 ? 64.070  -72.881 39.277  1.00 53.36  ? 519 ILE E CB   1 
ATOM   8378  C  CG1  . ILE E 1 312 ? 63.741  -71.404 39.076  1.00 48.22  ? 519 ILE E CG1  1 
ATOM   8379  C  CG2  . ILE E 1 312 ? 63.522  -73.389 40.599  1.00 52.29  ? 519 ILE E CG2  1 
ATOM   8380  C  CD1  . ILE E 1 312 ? 62.275  -71.121 39.103  1.00 50.44  ? 519 ILE E CD1  1 
ATOM   8381  N  N    . ARG E 1 313 ? 66.320  -75.014 40.537  1.00 58.22  ? 520 ARG E N    1 
ATOM   8382  C  CA   . ARG E 1 313 ? 66.682  -76.395 40.827  1.00 57.69  ? 520 ARG E CA   1 
ATOM   8383  C  C    . ARG E 1 313 ? 65.475  -77.316 40.691  1.00 56.36  ? 520 ARG E C    1 
ATOM   8384  O  O    . ARG E 1 313 ? 64.390  -77.011 41.191  1.00 58.57  ? 520 ARG E O    1 
ATOM   8385  C  CB   . ARG E 1 313 ? 67.250  -76.493 42.234  1.00 56.99  ? 520 ARG E CB   1 
ATOM   8386  C  CG   . ARG E 1 313 ? 68.182  -77.671 42.431  1.00 59.19  ? 520 ARG E CG   1 
ATOM   8387  C  CD   . ARG E 1 313 ? 68.588  -77.756 43.867  1.00 56.61  ? 520 ARG E CD   1 
ATOM   8388  N  NE   . ARG E 1 313 ? 69.423  -78.916 44.142  1.00 64.35  ? 520 ARG E NE   1 
ATOM   8389  C  CZ   . ARG E 1 313 ? 70.731  -78.856 44.366  1.00 63.00  ? 520 ARG E CZ   1 
ATOM   8390  N  NH1  . ARG E 1 313 ? 71.361  -77.687 44.338  1.00 56.25  ? 520 ARG E NH1  1 
ATOM   8391  N  NH2  . ARG E 1 313 ? 71.404  -79.967 44.622  1.00 63.51  ? 520 ARG E NH2  1 
ATOM   8392  N  N    . GLU E 1 314 ? 65.670  -78.464 40.039  1.00 57.87  ? 521 GLU E N    1 
ATOM   8393  C  CA   . GLU E 1 314 ? 64.536  -79.347 39.779  1.00 61.37  ? 521 GLU E CA   1 
ATOM   8394  C  C    . GLU E 1 314 ? 63.873  -79.794 41.080  1.00 58.81  ? 521 GLU E C    1 
ATOM   8395  O  O    . GLU E 1 314 ? 62.642  -79.850 41.165  1.00 60.43  ? 521 GLU E O    1 
ATOM   8396  C  CB   . GLU E 1 314 ? 64.988  -80.543 38.944  1.00 60.33  ? 521 GLU E CB   1 
ATOM   8397  C  CG   . GLU E 1 314 ? 63.931  -81.054 37.977  1.00 70.40  ? 521 GLU E CG   1 
ATOM   8398  C  CD   . GLU E 1 314 ? 64.333  -82.363 37.289  1.00 74.16  ? 521 GLU E CD   1 
ATOM   8399  O  OE1  . GLU E 1 314 ? 63.456  -83.246 37.119  1.00 77.44  ? 521 GLU E OE1  1 
ATOM   8400  O  OE2  . GLU E 1 314 ? 65.516  -82.504 36.909  1.00 70.81  ? 521 GLU E OE2  1 
ATOM   8401  N  N    . SER E 1 315 ? 64.664  -80.058 42.126  1.00 58.95  ? 522 SER E N    1 
ATOM   8402  C  CA   . SER E 1 315 ? 64.071  -80.525 43.375  1.00 55.99  ? 522 SER E CA   1 
ATOM   8403  C  C    . SER E 1 315 ? 63.345  -79.426 44.145  1.00 61.18  ? 522 SER E C    1 
ATOM   8404  O  O    . SER E 1 315 ? 62.605  -79.744 45.083  1.00 62.94  ? 522 SER E O    1 
ATOM   8405  C  CB   . SER E 1 315 ? 65.123  -81.186 44.279  1.00 59.21  ? 522 SER E CB   1 
ATOM   8406  O  OG   . SER E 1 315 ? 66.258  -80.361 44.507  1.00 67.70  ? 522 SER E OG   1 
ATOM   8407  N  N    . LYS E 1 316 ? 63.502  -78.155 43.769  1.00 63.06  ? 523 LYS E N    1 
ATOM   8408  C  CA   . LYS E 1 316 ? 62.808  -77.067 44.451  1.00 62.74  ? 523 LYS E CA   1 
ATOM   8409  C  C    . LYS E 1 316 ? 61.781  -76.380 43.565  1.00 60.15  ? 523 LYS E C    1 
ATOM   8410  O  O    . LYS E 1 316 ? 61.049  -75.491 44.043  1.00 59.60  ? 523 LYS E O    1 
ATOM   8411  C  CB   . LYS E 1 316 ? 63.815  -76.030 44.983  1.00 56.80  ? 523 LYS E CB   1 
ATOM   8412  C  CG   . LYS E 1 316 ? 65.026  -76.639 45.713  1.00 63.59  ? 523 LYS E CG   1 
ATOM   8413  C  CD   . LYS E 1 316 ? 64.738  -76.986 47.184  1.00 66.66  ? 523 LYS E CD   1 
ATOM   8414  C  CE   . LYS E 1 316 ? 65.872  -77.852 47.740  1.00 67.13  ? 523 LYS E CE   1 
ATOM   8415  N  NZ   . LYS E 1 316 ? 65.613  -78.415 49.091  1.00 64.17  ? 523 LYS E NZ   1 
ATOM   8416  N  N    . LEU E 1 317 ? 61.686  -76.786 42.298  1.00 57.76  ? 524 LEU E N    1 
ATOM   8417  C  CA   . LEU E 1 317 ? 60.858  -76.054 41.340  1.00 63.69  ? 524 LEU E CA   1 
ATOM   8418  C  C    . LEU E 1 317 ? 59.397  -76.011 41.769  1.00 63.88  ? 524 LEU E C    1 
ATOM   8419  O  O    . LEU E 1 317 ? 58.739  -74.973 41.643  1.00 69.16  ? 524 LEU E O    1 
ATOM   8420  C  CB   . LEU E 1 317 ? 60.988  -76.676 39.949  1.00 58.80  ? 524 LEU E CB   1 
ATOM   8421  C  CG   . LEU E 1 317 ? 60.203  -75.918 38.889  1.00 62.08  ? 524 LEU E CG   1 
ATOM   8422  C  CD1  . LEU E 1 317 ? 61.148  -75.073 38.022  1.00 63.93  ? 524 LEU E CD1  1 
ATOM   8423  C  CD2  . LEU E 1 317 ? 59.422  -76.885 38.052  1.00 67.46  ? 524 LEU E CD2  1 
ATOM   8424  N  N    . SER E 1 318 ? 58.872  -77.127 42.283  1.00 63.76  ? 525 SER E N    1 
ATOM   8425  C  CA   . SER E 1 318 ? 57.476  -77.142 42.695  1.00 60.90  ? 525 SER E CA   1 
ATOM   8426  C  C    . SER E 1 318 ? 57.246  -76.242 43.897  1.00 62.85  ? 525 SER E C    1 
ATOM   8427  O  O    . SER E 1 318 ? 56.139  -75.722 44.087  1.00 64.14  ? 525 SER E O    1 
ATOM   8428  C  CB   . SER E 1 318 ? 57.027  -78.576 42.990  1.00 65.32  ? 525 SER E CB   1 
ATOM   8429  O  OG   . SER E 1 318 ? 57.629  -79.062 44.176  1.00 66.72  ? 525 SER E OG   1 
ATOM   8430  N  N    . GLU E 1 319 ? 58.271  -76.033 44.720  1.00 64.43  ? 526 GLU E N    1 
ATOM   8431  C  CA   . GLU E 1 319 ? 58.094  -75.087 45.813  1.00 63.79  ? 526 GLU E CA   1 
ATOM   8432  C  C    . GLU E 1 319 ? 58.336  -73.654 45.351  1.00 64.29  ? 526 GLU E C    1 
ATOM   8433  O  O    . GLU E 1 319 ? 57.553  -72.749 45.674  1.00 62.59  ? 526 GLU E O    1 
ATOM   8434  C  CB   . GLU E 1 319 ? 59.006  -75.451 46.972  1.00 59.33  ? 526 GLU E CB   1 
ATOM   8435  C  CG   . GLU E 1 319 ? 58.592  -74.782 48.250  1.00 67.16  ? 526 GLU E CG   1 
ATOM   8436  C  CD   . GLU E 1 319 ? 59.709  -74.736 49.264  1.00 69.76  ? 526 GLU E CD   1 
ATOM   8437  O  OE1  . GLU E 1 319 ? 59.756  -73.757 50.039  1.00 69.35  ? 526 GLU E OE1  1 
ATOM   8438  O  OE2  . GLU E 1 319 ? 60.531  -75.684 49.283  1.00 70.85  ? 526 GLU E OE2  1 
ATOM   8439  N  N    . VAL E 1 320 ? 59.399  -73.439 44.573  1.00 61.32  ? 527 VAL E N    1 
ATOM   8440  C  CA   . VAL E 1 320 ? 59.720  -72.091 44.116  1.00 65.75  ? 527 VAL E CA   1 
ATOM   8441  C  C    . VAL E 1 320 ? 58.570  -71.524 43.302  1.00 68.44  ? 527 VAL E C    1 
ATOM   8442  O  O    . VAL E 1 320 ? 58.265  -70.325 43.370  1.00 68.93  ? 527 VAL E O    1 
ATOM   8443  C  CB   . VAL E 1 320 ? 61.029  -72.096 43.307  1.00 67.10  ? 527 VAL E CB   1 
ATOM   8444  C  CG1  . VAL E 1 320 ? 61.297  -70.718 42.683  1.00 57.45  ? 527 VAL E CG1  1 
ATOM   8445  C  CG2  . VAL E 1 320 ? 62.188  -72.546 44.178  1.00 62.25  ? 527 VAL E CG2  1 
ATOM   8446  N  N    . LEU E 1 321 ? 57.901  -72.375 42.533  1.00 69.62  ? 528 LEU E N    1 
ATOM   8447  C  CA   . LEU E 1 321 ? 56.825  -71.933 41.660  1.00 69.37  ? 528 LEU E CA   1 
ATOM   8448  C  C    . LEU E 1 321 ? 55.451  -72.382 42.162  1.00 70.72  ? 528 LEU E C    1 
ATOM   8449  O  O    . LEU E 1 321 ? 54.521  -72.553 41.372  1.00 74.48  ? 528 LEU E O    1 
ATOM   8450  C  CB   . LEU E 1 321 ? 57.094  -72.423 40.241  1.00 64.46  ? 528 LEU E CB   1 
ATOM   8451  C  CG   . LEU E 1 321 ? 58.448  -71.950 39.708  1.00 69.33  ? 528 LEU E CG   1 
ATOM   8452  C  CD1  . LEU E 1 321 ? 58.548  -72.203 38.208  1.00 68.27  ? 528 LEU E CD1  1 
ATOM   8453  C  CD2  . LEU E 1 321 ? 58.703  -70.466 40.032  1.00 64.23  ? 528 LEU E CD2  1 
ATOM   8454  N  N    . GLN E 1 322 ? 55.315  -72.574 43.476  1.00 69.24  ? 529 GLN E N    1 
ATOM   8455  C  CA   . GLN E 1 322 ? 54.016  -72.849 44.074  1.00 71.54  ? 529 GLN E CA   1 
ATOM   8456  C  C    . GLN E 1 322 ? 52.967  -71.873 43.555  1.00 73.80  ? 529 GLN E C    1 
ATOM   8457  O  O    . GLN E 1 322 ? 53.251  -70.698 43.304  1.00 77.11  ? 529 GLN E O    1 
ATOM   8458  C  CB   . GLN E 1 322 ? 54.104  -72.749 45.599  1.00 72.76  ? 529 GLN E CB   1 
ATOM   8459  C  CG   . GLN E 1 322 ? 54.515  -71.359 46.105  1.00 72.16  ? 529 GLN E CG   1 
ATOM   8460  C  CD   . GLN E 1 322 ? 54.437  -71.234 47.618  1.00 80.70  ? 529 GLN E CD   1 
ATOM   8461  O  OE1  . GLN E 1 322 ? 55.442  -71.406 48.324  1.00 80.94  ? 529 GLN E OE1  1 
ATOM   8462  N  NE2  . GLN E 1 322 ? 53.240  -70.932 48.130  1.00 77.77  ? 529 GLN E NE2  1 
ATOM   8463  N  N    . ALA E 1 323 ? 51.743  -72.370 43.476  1.00 81.24  ? 530 ALA E N    1 
ATOM   8464  C  CA   . ALA E 1 323 ? 50.630  -71.522 43.021  1.00 80.45  ? 530 ALA E CA   1 
ATOM   8465  C  C    . ALA E 1 323 ? 50.386  -70.416 44.038  1.00 78.10  ? 530 ALA E C    1 
ATOM   8466  O  O    . ALA E 1 323 ? 50.276  -70.707 45.239  1.00 78.35  ? 530 ALA E O    1 
ATOM   8467  C  CB   . ALA E 1 323 ? 49.405  -72.369 42.836  1.00 84.73  ? 530 ALA E CB   1 
ATOM   8468  N  N    . VAL E 1 324 ? 50.333  -69.190 43.554  1.00 76.46  ? 531 VAL E N    1 
ATOM   8469  C  CA   . VAL E 1 324 ? 50.039  -68.054 44.411  1.00 77.51  ? 531 VAL E CA   1 
ATOM   8470  C  C    . VAL E 1 324 ? 48.587  -67.691 44.171  1.00 79.85  ? 531 VAL E C    1 
ATOM   8471  O  O    . VAL E 1 324 ? 48.211  -67.340 43.044  1.00 76.75  ? 531 VAL E O    1 
ATOM   8472  C  CB   . VAL E 1 324 ? 50.970  -66.869 44.129  1.00 76.06  ? 531 VAL E CB   1 
ATOM   8473  C  CG1  . VAL E 1 324 ? 50.522  -65.655 44.914  1.00 73.79  ? 531 VAL E CG1  1 
ATOM   8474  C  CG2  . VAL E 1 324 ? 52.408  -67.239 44.483  1.00 74.72  ? 531 VAL E CG2  1 
ATOM   8475  N  N    . THR E 1 325 ? 47.770  -67.818 45.219  1.00 76.22  ? 532 THR E N    1 
ATOM   8476  C  CA   . THR E 1 325 ? 46.352  -67.489 45.196  1.00 80.79  ? 532 THR E CA   1 
ATOM   8477  C  C    . THR E 1 325 ? 46.113  -66.208 45.986  1.00 78.71  ? 532 THR E C    1 
ATOM   8478  O  O    . THR E 1 325 ? 47.032  -65.628 46.572  1.00 74.99  ? 532 THR E O    1 
ATOM   8479  C  CB   . THR E 1 325 ? 45.503  -68.631 45.771  1.00 76.73  ? 532 THR E CB   1 
ATOM   8480  O  OG1  . THR E 1 325 ? 45.371  -68.465 47.191  1.00 76.42  ? 532 THR E OG1  1 
ATOM   8481  C  CG2  . THR E 1 325 ? 46.151  -69.972 45.483  1.00 82.24  ? 532 THR E CG2  1 
ATOM   8482  N  N    . ASP E 1 326 ? 44.850  -65.777 46.005  1.00 79.99  ? 533 ASP E N    1 
ATOM   8483  C  CA   . ASP E 1 326 ? 44.463  -64.639 46.823  1.00 73.64  ? 533 ASP E CA   1 
ATOM   8484  C  C    . ASP E 1 326 ? 44.345  -65.005 48.285  1.00 76.32  ? 533 ASP E C    1 
ATOM   8485  O  O    . ASP E 1 326 ? 44.340  -64.107 49.135  1.00 80.20  ? 533 ASP E O    1 
ATOM   8486  C  CB   . ASP E 1 326 ? 43.152  -64.056 46.325  1.00 69.44  ? 533 ASP E CB   1 
ATOM   8487  C  CG   . ASP E 1 326 ? 43.351  -63.186 45.117  1.00 70.47  ? 533 ASP E CG   1 
ATOM   8488  O  OD1  . ASP E 1 326 ? 43.818  -62.049 45.294  1.00 76.65  ? 533 ASP E OD1  1 
ATOM   8489  O  OD2  . ASP E 1 326 ? 43.065  -63.639 43.993  1.00 74.55  ? 533 ASP E OD2  1 
ATOM   8490  N  N    . HIS E 1 327 ? 44.256  -66.303 48.592  1.00 78.91  ? 534 HIS E N    1 
ATOM   8491  C  CA   . HIS E 1 327 ? 44.349  -66.744 49.977  1.00 79.33  ? 534 HIS E CA   1 
ATOM   8492  C  C    . HIS E 1 327 ? 45.718  -66.437 50.562  1.00 80.60  ? 534 HIS E C    1 
ATOM   8493  O  O    . HIS E 1 327 ? 45.876  -66.458 51.786  1.00 84.44  ? 534 HIS E O    1 
ATOM   8494  C  CB   . HIS E 1 327 ? 44.049  -68.239 50.079  1.00 75.92  ? 534 HIS E CB   1 
ATOM   8495  N  N    . ASP E 1 328 ? 46.704  -66.134 49.713  1.00 80.38  ? 535 ASP E N    1 
ATOM   8496  C  CA   . ASP E 1 328 ? 48.024  -65.708 50.161  1.00 77.93  ? 535 ASP E CA   1 
ATOM   8497  C  C    . ASP E 1 328 ? 48.068  -64.207 50.444  1.00 77.05  ? 535 ASP E C    1 
ATOM   8498  O  O    . ASP E 1 328 ? 48.561  -63.785 51.496  1.00 78.27  ? 535 ASP E O    1 
ATOM   8499  C  CB   . ASP E 1 328 ? 49.073  -66.087 49.115  1.00 75.21  ? 535 ASP E CB   1 
ATOM   8500  C  CG   . ASP E 1 328 ? 49.088  -67.568 48.814  1.00 79.87  ? 535 ASP E CG   1 
ATOM   8501  O  OD1  . ASP E 1 328 ? 49.088  -68.381 49.767  1.00 82.75  ? 535 ASP E OD1  1 
ATOM   8502  O  OD2  . ASP E 1 328 ? 49.102  -67.924 47.614  1.00 86.88  ? 535 ASP E OD2  1 
ATOM   8503  N  N    . ILE E 1 329 ? 47.550  -63.401 49.520  1.00 76.18  ? 536 ILE E N    1 
ATOM   8504  C  CA   . ILE E 1 329 ? 47.437  -61.948 49.657  1.00 74.07  ? 536 ILE E CA   1 
ATOM   8505  C  C    . ILE E 1 329 ? 46.550  -61.590 50.849  1.00 78.93  ? 536 ILE E C    1 
ATOM   8506  O  O    . ILE E 1 329 ? 45.339  -61.859 50.825  1.00 78.14  ? 536 ILE E O    1 
ATOM   8507  C  CB   . ILE E 1 329 ? 46.883  -61.323 48.365  1.00 74.33  ? 536 ILE E CB   1 
ATOM   8508  C  CG1  . ILE E 1 329 ? 47.685  -61.794 47.151  1.00 71.01  ? 536 ILE E CG1  1 
ATOM   8509  C  CG2  . ILE E 1 329 ? 46.869  -59.807 48.467  1.00 76.35  ? 536 ILE E CG2  1 
ATOM   8510  C  CD1  . ILE E 1 329 ? 47.382  -61.037 45.888  1.00 69.79  ? 536 ILE E CD1  1 
ATOM   8511  N  N    . PRO E 1 330 ? 47.098  -60.969 51.897  1.00 80.09  ? 537 PRO E N    1 
ATOM   8512  C  CA   . PRO E 1 330 ? 46.270  -60.591 53.053  1.00 78.30  ? 537 PRO E CA   1 
ATOM   8513  C  C    . PRO E 1 330 ? 45.370  -59.398 52.757  1.00 84.64  ? 537 PRO E C    1 
ATOM   8514  O  O    . PRO E 1 330 ? 45.763  -58.459 52.062  1.00 86.50  ? 537 PRO E O    1 
ATOM   8515  C  CB   . PRO E 1 330 ? 47.304  -60.243 54.132  1.00 82.42  ? 537 PRO E CB   1 
ATOM   8516  C  CG   . PRO E 1 330 ? 48.647  -60.649 53.575  1.00 76.82  ? 537 PRO E CG   1 
ATOM   8517  C  CD   . PRO E 1 330 ? 48.514  -60.631 52.097  1.00 73.12  ? 537 PRO E CD   1 
ATOM   8518  N  N    . GLN E 1 331 ? 44.157  -59.427 53.332  1.00 89.71  ? 538 GLN E N    1 
ATOM   8519  C  CA   . GLN E 1 331 ? 43.187  -58.346 53.143  1.00 85.56  ? 538 GLN E CA   1 
ATOM   8520  C  C    . GLN E 1 331 ? 43.681  -56.998 53.668  1.00 90.61  ? 538 GLN E C    1 
ATOM   8521  O  O    . GLN E 1 331 ? 43.140  -55.957 53.271  1.00 88.66  ? 538 GLN E O    1 
ATOM   8522  N  N    . GLN E 1 332 ? 44.688  -56.997 54.552  1.00 93.66  ? 539 GLN E N    1 
ATOM   8523  C  CA   . GLN E 1 332 ? 45.282  -55.752 55.043  1.00 90.06  ? 539 GLN E CA   1 
ATOM   8524  C  C    . GLN E 1 332 ? 45.754  -54.878 53.892  1.00 87.93  ? 539 GLN E C    1 
ATOM   8525  O  O    . GLN E 1 332 ? 45.394  -53.700 53.796  1.00 90.18  ? 539 GLN E O    1 
ATOM   8526  C  CB   . GLN E 1 332 ? 46.457  -56.064 55.975  1.00 87.49  ? 539 GLN E CB   1 
ATOM   8527  C  CG   . GLN E 1 332 ? 46.085  -56.603 57.348  1.00 88.83  ? 539 GLN E CG   1 
ATOM   8528  C  CD   . GLN E 1 332 ? 45.580  -58.032 57.312  1.00 93.41  ? 539 GLN E CD   1 
ATOM   8529  O  OE1  . GLN E 1 332 ? 45.660  -58.706 56.284  1.00 91.57  ? 539 GLN E OE1  1 
ATOM   8530  N  NE2  . GLN E 1 332 ? 45.056  -58.505 58.441  1.00 95.41  ? 539 GLN E NE2  1 
ATOM   8531  N  N    . LEU E 1 333 ? 46.578  -55.445 53.012  1.00 88.72  ? 540 LEU E N    1 
ATOM   8532  C  CA   . LEU E 1 333 ? 47.077  -54.738 51.844  1.00 86.97  ? 540 LEU E CA   1 
ATOM   8533  C  C    . LEU E 1 333 ? 46.244  -54.994 50.603  1.00 88.05  ? 540 LEU E C    1 
ATOM   8534  O  O    . LEU E 1 333 ? 46.302  -54.192 49.664  1.00 91.38  ? 540 LEU E O    1 
ATOM   8535  N  N    . VAL E 1 334 ? 45.478  -56.089 50.580  1.00 86.68  ? 541 VAL E N    1 
ATOM   8536  C  CA   . VAL E 1 334 ? 44.565  -56.361 49.478  1.00 83.71  ? 541 VAL E CA   1 
ATOM   8537  C  C    . VAL E 1 334 ? 43.461  -55.324 49.426  1.00 87.06  ? 541 VAL E C    1 
ATOM   8538  O  O    . VAL E 1 334 ? 42.813  -55.160 48.387  1.00 92.18  ? 541 VAL E O    1 
ATOM   8539  N  N    . GLU E 1 335 ? 43.225  -54.625 50.534  1.00 87.56  ? 542 GLU E N    1 
ATOM   8540  C  CA   . GLU E 1 335 ? 42.332  -53.478 50.592  1.00 93.43  ? 542 GLU E CA   1 
ATOM   8541  C  C    . GLU E 1 335 ? 43.032  -52.188 50.994  1.00 93.41  ? 542 GLU E C    1 
ATOM   8542  O  O    . GLU E 1 335 ? 42.583  -51.109 50.594  1.00 97.52  ? 542 GLU E O    1 
ATOM   8543  N  N    . ARG E 1 336 ? 44.102  -52.262 51.792  1.00 92.69  ? 543 ARG E N    1 
ATOM   8544  C  CA   . ARG E 1 336 ? 44.991  -51.114 51.935  1.00 91.29  ? 543 ARG E CA   1 
ATOM   8545  C  C    . ARG E 1 336 ? 45.540  -50.681 50.582  1.00 93.63  ? 543 ARG E C    1 
ATOM   8546  O  O    . ARG E 1 336 ? 45.894  -49.509 50.402  1.00 97.51  ? 543 ARG E O    1 
ATOM   8547  N  N    . LEU E 1 337 ? 45.622  -51.608 49.623  1.00 92.95  ? 544 LEU E N    1 
ATOM   8548  C  CA   . LEU E 1 337 ? 45.929  -51.257 48.242  1.00 89.97  ? 544 LEU E CA   1 
ATOM   8549  C  C    . LEU E 1 337 ? 44.779  -50.422 47.699  1.00 91.74  ? 544 LEU E C    1 
ATOM   8550  O  O    . LEU E 1 337 ? 44.926  -49.213 47.505  1.00 89.76  ? 544 LEU E O    1 
ATOM   8551  N  N    . GLN E 1 338 ? 43.616  -51.057 47.522  1.00 98.84  ? 545 GLN E N    1 
ATOM   8552  C  CA   . GLN E 1 338 ? 42.418  -50.378 46.949  1.00 97.09  ? 545 GLN E CA   1 
ATOM   8553  C  C    . GLN E 1 338 ? 42.072  -49.083 47.687  1.00 96.78  ? 545 GLN E C    1 
ATOM   8554  O  O    . GLN E 1 338 ? 41.397  -48.243 47.077  1.00 98.26  ? 545 GLN E O    1 
ATOM   8555  N  N    . GLU E 1 339 ? 42.493  -48.938 48.945  1.00 97.16  ? 546 GLU E N    1 
ATOM   8556  C  CA   . GLU E 1 339 ? 42.253  -47.689 49.664  1.00 95.90  ? 546 GLU E CA   1 
ATOM   8557  C  C    . GLU E 1 339 ? 42.709  -46.468 48.872  1.00 101.24 ? 546 GLU E C    1 
ATOM   8558  O  O    . GLU E 1 339 ? 42.119  -45.391 49.001  1.00 104.76 ? 546 GLU E O    1 
ATOM   8559  N  N    . GLU E 1 340 ? 43.702  -46.636 48.005  1.00 101.30 ? 547 GLU E N    1 
ATOM   8560  C  CA   . GLU E 1 340 ? 44.123  -45.494 47.156  1.00 97.75  ? 547 GLU E CA   1 
ATOM   8561  C  C    . GLU E 1 340 ? 43.170  -45.372 45.963  1.00 97.95  ? 547 GLU E C    1 
ATOM   8562  O  O    . GLU E 1 340 ? 43.322  -46.178 45.028  1.00 100.95 ? 547 GLU E O    1 
ATOM   8563  C  CB   . GLU E 1 340 ? 45.575  -45.680 46.728  1.00 101.15 ? 547 GLU E CB   1 
ATOM   8564  N  N    . MET F 2 1   ? 96.805  -55.420 53.467  1.00 55.22  ? 1   MET F N    1 
ATOM   8565  C  CA   . MET F 2 1   ? 96.360  -56.803 53.327  1.00 56.24  ? 1   MET F CA   1 
ATOM   8566  C  C    . MET F 2 1   ? 96.075  -57.093 51.868  1.00 58.30  ? 1   MET F C    1 
ATOM   8567  O  O    . MET F 2 1   ? 95.746  -56.182 51.105  1.00 59.32  ? 1   MET F O    1 
ATOM   8568  C  CB   . MET F 2 1   ? 95.114  -57.064 54.180  1.00 51.49  ? 1   MET F CB   1 
ATOM   8569  C  CG   . MET F 2 1   ? 93.922  -56.287 53.721  1.00 54.91  ? 1   MET F CG   1 
ATOM   8570  S  SD   . MET F 2 1   ? 92.415  -56.649 54.626  1.00 63.24  ? 1   MET F SD   1 
ATOM   8571  C  CE   . MET F 2 1   ? 91.351  -55.474 53.812  1.00 54.89  ? 1   MET F CE   1 
ATOM   8572  N  N    . GLN F 2 2   ? 96.176  -58.356 51.480  1.00 52.81  ? 2   GLN F N    1 
ATOM   8573  C  CA   . GLN F 2 2   ? 96.014  -58.758 50.091  1.00 59.54  ? 2   GLN F CA   1 
ATOM   8574  C  C    . GLN F 2 2   ? 94.674  -59.457 49.905  1.00 53.36  ? 2   GLN F C    1 
ATOM   8575  O  O    . GLN F 2 2   ? 94.448  -60.533 50.471  1.00 56.29  ? 2   GLN F O    1 
ATOM   8576  C  CB   . GLN F 2 2   ? 97.151  -59.678 49.656  1.00 52.67  ? 2   GLN F CB   1 
ATOM   8577  C  CG   . GLN F 2 2   ? 97.001  -60.203 48.258  1.00 50.85  ? 2   GLN F CG   1 
ATOM   8578  C  CD   . GLN F 2 2   ? 98.040  -61.272 47.951  1.00 55.11  ? 2   GLN F CD   1 
ATOM   8579  O  OE1  . GLN F 2 2   ? 97.844  -62.439 48.277  1.00 47.60  ? 2   GLN F OE1  1 
ATOM   8580  N  NE2  . GLN F 2 2   ? 99.171  -60.864 47.356  1.00 45.91  ? 2   GLN F NE2  1 
ATOM   8581  N  N    . ILE F 2 3   ? 93.845  -58.852 49.063  1.00 44.83  ? 3   ILE F N    1 
ATOM   8582  C  CA   . ILE F 2 3   ? 92.547  -59.455 48.685  1.00 48.01  ? 3   ILE F CA   1 
ATOM   8583  C  C    . ILE F 2 3   ? 92.661  -59.945 47.241  1.00 47.38  ? 3   ILE F C    1 
ATOM   8584  O  O    . ILE F 2 3   ? 93.719  -59.785 46.628  1.00 50.92  ? 3   ILE F O    1 
ATOM   8585  C  CB   . ILE F 2 3   ? 91.425  -58.415 48.824  1.00 51.44  ? 3   ILE F CB   1 
ATOM   8586  C  CG1  . ILE F 2 3   ? 91.650  -57.222 47.894  1.00 44.90  ? 3   ILE F CG1  1 
ATOM   8587  C  CG2  . ILE F 2 3   ? 91.257  -57.988 50.270  1.00 49.83  ? 3   ILE F CG2  1 
ATOM   8588  C  CD1  . ILE F 2 3   ? 90.440  -56.354 47.713  1.00 44.26  ? 3   ILE F CD1  1 
ATOM   8589  N  N    . PHE F 2 4   ? 91.600  -60.535 46.723  1.00 45.16  ? 4   PHE F N    1 
ATOM   8590  C  CA   . PHE F 2 4   ? 91.585  -61.028 45.358  1.00 47.70  ? 4   PHE F CA   1 
ATOM   8591  C  C    . PHE F 2 4   ? 90.480  -60.312 44.603  1.00 50.02  ? 4   PHE F C    1 
ATOM   8592  O  O    . PHE F 2 4   ? 89.462  -59.939 45.185  1.00 53.10  ? 4   PHE F O    1 
ATOM   8593  C  CB   . PHE F 2 4   ? 91.332  -62.543 45.290  1.00 46.17  ? 4   PHE F CB   1 
ATOM   8594  C  CG   . PHE F 2 4   ? 92.373  -63.381 45.978  1.00 48.75  ? 4   PHE F CG   1 
ATOM   8595  C  CD1  . PHE F 2 4   ? 93.709  -63.263 45.657  1.00 50.03  ? 4   PHE F CD1  1 
ATOM   8596  C  CD2  . PHE F 2 4   ? 92.001  -64.330 46.917  1.00 55.25  ? 4   PHE F CD2  1 
ATOM   8597  C  CE1  . PHE F 2 4   ? 94.657  -64.064 46.277  1.00 50.23  ? 4   PHE F CE1  1 
ATOM   8598  C  CE2  . PHE F 2 4   ? 92.955  -65.138 47.547  1.00 47.51  ? 4   PHE F CE2  1 
ATOM   8599  C  CZ   . PHE F 2 4   ? 94.270  -64.997 47.227  1.00 47.35  ? 4   PHE F CZ   1 
ATOM   8600  N  N    . VAL F 2 5   ? 90.691  -60.094 43.310  1.00 46.54  ? 5   VAL F N    1 
ATOM   8601  C  CA   . VAL F 2 5   ? 89.633  -59.482 42.465  1.00 47.10  ? 5   VAL F CA   1 
ATOM   8602  C  C    . VAL F 2 5   ? 89.526  -60.323 41.198  1.00 51.89  ? 5   VAL F C    1 
ATOM   8603  O  O    . VAL F 2 5   ? 90.535  -60.503 40.527  1.00 51.22  ? 5   VAL F O    1 
ATOM   8604  C  CB   . VAL F 2 5   ? 89.885  -57.997 42.147  1.00 45.72  ? 5   VAL F CB   1 
ATOM   8605  C  CG1  . VAL F 2 5   ? 88.911  -57.458 41.113  1.00 47.71  ? 5   VAL F CG1  1 
ATOM   8606  C  CG2  . VAL F 2 5   ? 89.883  -57.115 43.384  1.00 44.21  ? 5   VAL F CG2  1 
ATOM   8607  N  N    . LYS F 2 6   ? 88.339  -60.846 40.919  1.00 49.22  ? 6   LYS F N    1 
ATOM   8608  C  CA   . LYS F 2 6   ? 88.090  -61.613 39.685  1.00 51.66  ? 6   LYS F CA   1 
ATOM   8609  C  C    . LYS F 2 6   ? 87.770  -60.597 38.599  1.00 53.23  ? 6   LYS F C    1 
ATOM   8610  O  O    . LYS F 2 6   ? 86.806  -59.855 38.778  1.00 53.29  ? 6   LYS F O    1 
ATOM   8611  C  CB   . LYS F 2 6   ? 86.923  -62.566 39.929  1.00 54.54  ? 6   LYS F CB   1 
ATOM   8612  C  CG   . LYS F 2 6   ? 87.272  -63.878 40.615  1.00 59.39  ? 6   LYS F CG   1 
ATOM   8613  C  CD   . LYS F 2 6   ? 86.297  -64.993 40.310  1.00 66.83  ? 6   LYS F CD   1 
ATOM   8614  C  CE   . LYS F 2 6   ? 86.935  -66.196 39.652  1.00 63.48  ? 6   LYS F CE   1 
ATOM   8615  N  NZ   . LYS F 2 6   ? 86.196  -67.443 39.952  1.00 68.34  ? 6   LYS F NZ   1 
ATOM   8616  N  N    . THR F 2 7   ? 88.528  -60.623 37.510  1.00 49.69  ? 7   THR F N    1 
ATOM   8617  C  CA   . THR F 2 7   ? 88.364  -59.621 36.431  1.00 54.31  ? 7   THR F CA   1 
ATOM   8618  C  C    . THR F 2 7   ? 87.247  -60.020 35.468  1.00 59.08  ? 7   THR F C    1 
ATOM   8619  O  O    . THR F 2 7   ? 86.569  -61.027 35.710  1.00 55.41  ? 7   THR F O    1 
ATOM   8620  C  CB   . THR F 2 7   ? 89.691  -59.433 35.698  1.00 53.04  ? 7   THR F CB   1 
ATOM   8621  O  OG1  . THR F 2 7   ? 89.966  -60.623 34.964  1.00 64.89  ? 7   THR F OG1  1 
ATOM   8622  C  CG2  . THR F 2 7   ? 90.833  -59.149 36.646  1.00 51.51  ? 7   THR F CG2  1 
ATOM   8623  N  N    . LEU F 2 8   ? 87.080  -59.245 34.403  1.00 59.62  ? 8   LEU F N    1 
ATOM   8624  C  CA   . LEU F 2 8   ? 86.047  -59.564 33.389  1.00 63.23  ? 8   LEU F CA   1 
ATOM   8625  C  C    . LEU F 2 8   ? 86.497  -60.789 32.591  1.00 61.81  ? 8   LEU F C    1 
ATOM   8626  O  O    . LEU F 2 8   ? 85.627  -61.443 32.007  1.00 65.79  ? 8   LEU F O    1 
ATOM   8627  C  CB   . LEU F 2 8   ? 85.838  -58.353 32.483  1.00 57.84  ? 8   LEU F CB   1 
ATOM   8628  C  CG   . LEU F 2 8   ? 85.794  -56.990 33.165  1.00 66.25  ? 8   LEU F CG   1 
ATOM   8629  C  CD1  . LEU F 2 8   ? 85.815  -55.890 32.120  1.00 62.30  ? 8   LEU F CD1  1 
ATOM   8630  C  CD2  . LEU F 2 8   ? 84.557  -56.860 34.034  1.00 63.25  ? 8   LEU F CD2  1 
ATOM   8631  N  N    . THR F 2 9   ? 87.792  -61.096 32.620  1.00 60.77  ? 9   THR F N    1 
ATOM   8632  C  CA   . THR F 2 9   ? 88.333  -62.294 31.924  1.00 65.00  ? 9   THR F CA   1 
ATOM   8633  C  C    . THR F 2 9   ? 88.091  -63.553 32.758  1.00 61.33  ? 9   THR F C    1 
ATOM   8634  O  O    . THR F 2 9   ? 88.301  -64.644 32.225  1.00 69.09  ? 9   THR F O    1 
ATOM   8635  C  CB   . THR F 2 9   ? 89.825  -62.137 31.611  1.00 63.47  ? 9   THR F CB   1 
ATOM   8636  O  OG1  . THR F 2 9   ? 90.573  -62.294 32.815  1.00 66.56  ? 9   THR F OG1  1 
ATOM   8637  C  CG2  . THR F 2 9   ? 90.161  -60.802 30.983  1.00 70.48  ? 9   THR F CG2  1 
ATOM   8638  N  N    . GLY F 2 10  ? 87.663  -63.404 34.006  1.00 60.93  ? 10  GLY F N    1 
ATOM   8639  C  CA   . GLY F 2 10  ? 87.425  -64.556 34.892  1.00 56.84  ? 10  GLY F CA   1 
ATOM   8640  C  C    . GLY F 2 10  ? 88.674  -64.900 35.667  1.00 61.51  ? 10  GLY F C    1 
ATOM   8641  O  O    . GLY F 2 10  ? 88.612  -65.819 36.485  1.00 63.92  ? 10  GLY F O    1 
ATOM   8642  N  N    . LYS F 2 11  ? 89.760  -64.168 35.428  1.00 61.87  ? 11  LYS F N    1 
ATOM   8643  C  CA   . LYS F 2 11  ? 91.057  -64.451 36.080  1.00 56.19  ? 11  LYS F CA   1 
ATOM   8644  C  C    . LYS F 2 11  ? 91.187  -63.627 37.354  1.00 59.73  ? 11  LYS F C    1 
ATOM   8645  O  O    . LYS F 2 11  ? 90.773  -62.469 37.352  1.00 58.65  ? 11  LYS F O    1 
ATOM   8646  C  CB   . LYS F 2 11  ? 92.201  -64.148 35.116  1.00 56.46  ? 11  LYS F CB   1 
ATOM   8647  N  N    . THR F 2 12  ? 91.769  -64.224 38.386  1.00 53.29  ? 12  THR F N    1 
ATOM   8648  C  CA   . THR F 2 12  ? 91.903  -63.549 39.691  1.00 50.73  ? 12  THR F CA   1 
ATOM   8649  C  C    . THR F 2 12  ? 93.199  -62.743 39.728  1.00 55.06  ? 12  THR F C    1 
ATOM   8650  O  O    . THR F 2 12  ? 94.243  -63.278 39.335  1.00 50.33  ? 12  THR F O    1 
ATOM   8651  C  CB   . THR F 2 12  ? 91.834  -64.568 40.833  1.00 53.59  ? 12  THR F CB   1 
ATOM   8652  O  OG1  . THR F 2 12  ? 92.987  -65.407 40.782  1.00 63.69  ? 12  THR F OG1  1 
ATOM   8653  C  CG2  . THR F 2 12  ? 90.596  -65.432 40.785  1.00 51.06  ? 12  THR F CG2  1 
ATOM   8654  N  N    . ILE F 2 13  ? 93.113  -61.494 40.176  1.00 50.66  ? 13  ILE F N    1 
ATOM   8655  C  CA   . ILE F 2 13  ? 94.341  -60.672 40.353  1.00 48.55  ? 13  ILE F CA   1 
ATOM   8656  C  C    . ILE F 2 13  ? 94.469  -60.330 41.831  1.00 49.27  ? 13  ILE F C    1 
ATOM   8657  O  O    . ILE F 2 13  ? 93.448  -60.234 42.511  1.00 53.23  ? 13  ILE F O    1 
ATOM   8658  C  CB   . ILE F 2 13  ? 94.339  -59.404 39.476  1.00 52.14  ? 13  ILE F CB   1 
ATOM   8659  C  CG1  . ILE F 2 13  ? 93.093  -58.542 39.685  1.00 51.86  ? 13  ILE F CG1  1 
ATOM   8660  C  CG2  . ILE F 2 13  ? 94.544  -59.754 38.011  1.00 41.88  ? 13  ILE F CG2  1 
ATOM   8661  C  CD1  . ILE F 2 13  ? 93.396  -57.109 40.029  1.00 48.73  ? 13  ILE F CD1  1 
ATOM   8662  N  N    . THR F 2 14  ? 95.695  -60.185 42.311  1.00 48.50  ? 14  THR F N    1 
ATOM   8663  C  CA   . THR F 2 14  ? 95.890  -59.747 43.709  1.00 52.48  ? 14  THR F CA   1 
ATOM   8664  C  C    . THR F 2 14  ? 95.755  -58.230 43.808  1.00 54.23  ? 14  THR F C    1 
ATOM   8665  O  O    . THR F 2 14  ? 96.123  -57.556 42.852  1.00 48.06  ? 14  THR F O    1 
ATOM   8666  C  CB   . THR F 2 14  ? 97.248  -60.218 44.232  1.00 50.74  ? 14  THR F CB   1 
ATOM   8667  O  OG1  . THR F 2 14  ? 98.281  -59.639 43.437  1.00 51.78  ? 14  THR F OG1  1 
ATOM   8668  C  CG2  . THR F 2 14  ? 97.366  -61.726 44.232  1.00 56.81  ? 14  THR F CG2  1 
ATOM   8669  N  N    . LEU F 2 15  ? 95.211  -57.730 44.917  1.00 52.90  ? 15  LEU F N    1 
ATOM   8670  C  CA   . LEU F 2 15  ? 95.170  -56.265 45.158  1.00 54.51  ? 15  LEU F CA   1 
ATOM   8671  C  C    . LEU F 2 15  ? 95.635  -56.015 46.592  1.00 58.49  ? 15  LEU F C    1 
ATOM   8672  O  O    . LEU F 2 15  ? 95.146  -56.692 47.491  1.00 60.54  ? 15  LEU F O    1 
ATOM   8673  C  CB   . LEU F 2 15  ? 93.761  -55.717 44.924  1.00 52.06  ? 15  LEU F CB   1 
ATOM   8674  C  CG   . LEU F 2 15  ? 93.690  -54.322 44.315  1.00 43.53  ? 15  LEU F CG   1 
ATOM   8675  C  CD1  . LEU F 2 15  ? 94.020  -54.365 42.835  1.00 40.69  ? 15  LEU F CD1  1 
ATOM   8676  C  CD2  . LEU F 2 15  ? 92.314  -53.725 44.531  1.00 45.92  ? 15  LEU F CD2  1 
ATOM   8677  N  N    . GLU F 2 16  ? 96.560  -55.080 46.778  1.00 55.89  ? 16  GLU F N    1 
ATOM   8678  C  CA   . GLU F 2 16  ? 97.048  -54.748 48.138  1.00 59.45  ? 16  GLU F CA   1 
ATOM   8679  C  C    . GLU F 2 16  ? 96.216  -53.595 48.678  1.00 65.58  ? 16  GLU F C    1 
ATOM   8680  O  O    . GLU F 2 16  ? 96.314  -52.486 48.140  1.00 59.49  ? 16  GLU F O    1 
ATOM   8681  C  CB   . GLU F 2 16  ? 98.539  -54.424 48.152  1.00 67.52  ? 16  GLU F CB   1 
ATOM   8682  C  CG   . GLU F 2 16  ? 99.129  -54.413 49.548  1.00 75.66  ? 16  GLU F CG   1 
ATOM   8683  C  CD   . GLU F 2 16  ? 99.241  -55.776 50.204  1.00 74.78  ? 16  GLU F CD   1 
ATOM   8684  O  OE1  . GLU F 2 16  ? 99.442  -56.769 49.481  1.00 93.68  ? 16  GLU F OE1  1 
ATOM   8685  O  OE2  . GLU F 2 16  ? 99.146  -55.836 51.439  1.00 71.17  ? 16  GLU F OE2  1 
ATOM   8686  N  N    . VAL F 2 17  ? 95.424  -53.881 49.702  1.00 65.20  ? 17  VAL F N    1 
ATOM   8687  C  CA   . VAL F 2 17  ? 94.509  -52.857 50.275  1.00 63.12  ? 17  VAL F CA   1 
ATOM   8688  C  C    . VAL F 2 17  ? 94.653  -52.785 51.789  1.00 61.42  ? 17  VAL F C    1 
ATOM   8689  O  O    . VAL F 2 17  ? 95.498  -53.467 52.341  1.00 60.72  ? 17  VAL F O    1 
ATOM   8690  C  CB   . VAL F 2 17  ? 93.048  -53.176 49.929  1.00 58.93  ? 17  VAL F CB   1 
ATOM   8691  C  CG1  . VAL F 2 17  ? 92.703  -52.853 48.486  1.00 57.77  ? 17  VAL F CG1  1 
ATOM   8692  C  CG2  . VAL F 2 17  ? 92.720  -54.618 50.253  1.00 58.95  ? 17  VAL F CG2  1 
ATOM   8693  N  N    . GLU F 2 18  ? 93.844  -51.949 52.418  1.00 62.41  ? 18  GLU F N    1 
ATOM   8694  C  CA   . GLU F 2 18  ? 93.873  -51.773 53.884  1.00 61.64  ? 18  GLU F CA   1 
ATOM   8695  C  C    . GLU F 2 18  ? 92.429  -51.873 54.359  1.00 61.08  ? 18  GLU F C    1 
ATOM   8696  O  O    . GLU F 2 18  ? 91.536  -51.489 53.600  1.00 62.71  ? 18  GLU F O    1 
ATOM   8697  C  CB   . GLU F 2 18  ? 94.489  -50.418 54.227  1.00 57.28  ? 18  GLU F CB   1 
ATOM   8698  C  CG   . GLU F 2 18  ? 96.000  -50.441 54.312  1.00 58.34  ? 18  GLU F CG   1 
ATOM   8699  C  CD   . GLU F 2 18  ? 96.530  -51.205 55.509  1.00 68.38  ? 18  GLU F CD   1 
ATOM   8700  O  OE1  . GLU F 2 18  ? 96.328  -50.734 56.641  1.00 67.66  ? 18  GLU F OE1  1 
ATOM   8701  O  OE2  . GLU F 2 18  ? 97.138  -52.269 55.305  1.00 70.88  ? 18  GLU F OE2  1 
ATOM   8702  N  N    . PRO F 2 19  ? 92.156  -52.416 55.554  1.00 52.06  ? 19  PRO F N    1 
ATOM   8703  C  CA   . PRO F 2 19  ? 90.794  -52.467 56.052  1.00 50.67  ? 19  PRO F CA   1 
ATOM   8704  C  C    . PRO F 2 19  ? 90.033  -51.142 55.936  1.00 58.66  ? 19  PRO F C    1 
ATOM   8705  O  O    . PRO F 2 19  ? 88.850  -51.185 55.738  1.00 67.77  ? 19  PRO F O    1 
ATOM   8706  C  CB   . PRO F 2 19  ? 91.048  -52.812 57.514  1.00 58.40  ? 19  PRO F CB   1 
ATOM   8707  C  CG   . PRO F 2 19  ? 92.246  -53.717 57.467  1.00 48.42  ? 19  PRO F CG   1 
ATOM   8708  C  CD   . PRO F 2 19  ? 93.130  -53.060 56.434  1.00 56.77  ? 19  PRO F CD   1 
ATOM   8709  N  N    . SER F 2 20  ? 90.721  -50.010 56.028  1.00 54.93  ? 20  SER F N    1 
ATOM   8710  C  CA   . SER F 2 20  ? 90.067  -48.715 56.006  1.00 55.61  ? 20  SER F CA   1 
ATOM   8711  C  C    . SER F 2 20  ? 90.037  -48.100 54.622  1.00 57.21  ? 20  SER F C    1 
ATOM   8712  O  O    . SER F 2 20  ? 89.519  -46.991 54.464  1.00 57.08  ? 20  SER F O    1 
ATOM   8713  C  CB   . SER F 2 20  ? 90.770  -47.760 56.968  1.00 58.09  ? 20  SER F CB   1 
ATOM   8714  O  OG   . SER F 2 20  ? 92.100  -47.513 56.533  1.00 64.80  ? 20  SER F OG   1 
ATOM   8715  N  N    . ASP F 2 21  ? 90.567  -48.811 53.642  1.00 58.45  ? 21  ASP F N    1 
ATOM   8716  C  CA   . ASP F 2 21  ? 90.485  -48.298 52.259  1.00 58.51  ? 21  ASP F CA   1 
ATOM   8717  C  C    . ASP F 2 21  ? 89.017  -48.224 51.857  1.00 60.90  ? 21  ASP F C    1 
ATOM   8718  O  O    . ASP F 2 21  ? 88.260  -49.148 52.176  1.00 58.15  ? 21  ASP F O    1 
ATOM   8719  C  CB   . ASP F 2 21  ? 91.350  -49.110 51.300  1.00 59.24  ? 21  ASP F CB   1 
ATOM   8720  C  CG   . ASP F 2 21  ? 92.759  -48.572 51.190  1.00 64.55  ? 21  ASP F CG   1 
ATOM   8721  O  OD1  . ASP F 2 21  ? 92.912  -47.354 51.003  1.00 65.03  ? 21  ASP F OD1  1 
ATOM   8722  O  OD2  . ASP F 2 21  ? 93.685  -49.377 51.288  1.00 63.32  ? 21  ASP F OD2  1 
ATOM   8723  N  N    . THR F 2 22  ? 88.649  -47.148 51.182  1.00 57.74  ? 22  THR F N    1 
ATOM   8724  C  CA   . THR F 2 22  ? 87.263  -46.944 50.728  1.00 56.03  ? 22  THR F CA   1 
ATOM   8725  C  C    . THR F 2 22  ? 87.076  -47.664 49.398  1.00 57.72  ? 22  THR F C    1 
ATOM   8726  O  O    . THR F 2 22  ? 88.067  -48.023 48.771  1.00 56.45  ? 22  THR F O    1 
ATOM   8727  C  CB   . THR F 2 22  ? 86.961  -45.450 50.590  1.00 56.29  ? 22  THR F CB   1 
ATOM   8728  O  OG1  . THR F 2 22  ? 87.727  -44.908 49.515  1.00 58.17  ? 22  THR F OG1  1 
ATOM   8729  C  CG2  . THR F 2 22  ? 87.241  -44.679 51.860  1.00 58.45  ? 22  THR F CG2  1 
ATOM   8730  N  N    . ILE F 2 23  ? 85.830  -47.819 48.973  1.00 57.44  ? 23  ILE F N    1 
ATOM   8731  C  CA   . ILE F 2 23  ? 85.546  -48.542 47.705  1.00 58.59  ? 23  ILE F CA   1 
ATOM   8732  C  C    . ILE F 2 23  ? 86.108  -47.695 46.565  1.00 56.62  ? 23  ILE F C    1 
ATOM   8733  O  O    . ILE F 2 23  ? 86.550  -48.279 45.581  1.00 59.19  ? 23  ILE F O    1 
ATOM   8734  C  CB   . ILE F 2 23  ? 84.043  -48.871 47.593  1.00 54.19  ? 23  ILE F CB   1 
ATOM   8735  C  CG1  . ILE F 2 23  ? 83.559  -49.682 48.799  1.00 53.44  ? 23  ILE F CG1  1 
ATOM   8736  C  CG2  . ILE F 2 23  ? 83.711  -49.567 46.284  1.00 50.78  ? 23  ILE F CG2  1 
ATOM   8737  C  CD1  . ILE F 2 23  ? 84.448  -50.837 49.186  1.00 53.90  ? 23  ILE F CD1  1 
ATOM   8738  N  N    . GLU F 2 24  ? 86.157  -46.377 46.735  1.00 60.30  ? 24  GLU F N    1 
ATOM   8739  C  CA   . GLU F 2 24  ? 86.774  -45.487 45.721  1.00 58.40  ? 24  GLU F CA   1 
ATOM   8740  C  C    . GLU F 2 24  ? 88.267  -45.792 45.621  1.00 55.04  ? 24  GLU F C    1 
ATOM   8741  O  O    . GLU F 2 24  ? 88.766  -45.859 44.503  1.00 54.95  ? 24  GLU F O    1 
ATOM   8742  C  CB   . GLU F 2 24  ? 86.574  -44.030 46.123  1.00 56.81  ? 24  GLU F CB   1 
ATOM   8743  C  CG   . GLU F 2 24  ? 85.127  -43.592 46.132  1.00 58.41  ? 24  GLU F CG   1 
ATOM   8744  C  CD   . GLU F 2 24  ? 84.603  -43.172 47.492  1.00 62.74  ? 24  GLU F CD   1 
ATOM   8745  O  OE1  . GLU F 2 24  ? 83.992  -42.093 47.579  1.00 71.30  ? 24  GLU F OE1  1 
ATOM   8746  O  OE2  . GLU F 2 24  ? 84.795  -43.930 48.454  1.00 64.49  ? 24  GLU F OE2  1 
ATOM   8747  N  N    . ASN F 2 25  ? 88.937  -45.968 46.757  1.00 54.76  ? 25  ASN F N    1 
ATOM   8748  C  CA   . ASN F 2 25  ? 90.396  -46.240 46.779  1.00 58.85  ? 25  ASN F CA   1 
ATOM   8749  C  C    . ASN F 2 25  ? 90.668  -47.616 46.180  1.00 55.05  ? 25  ASN F C    1 
ATOM   8750  O  O    . ASN F 2 25  ? 91.698  -47.771 45.531  1.00 54.42  ? 25  ASN F O    1 
ATOM   8751  C  CB   . ASN F 2 25  ? 90.975  -46.162 48.193  1.00 62.61  ? 25  ASN F CB   1 
ATOM   8752  C  CG   . ASN F 2 25  ? 90.854  -44.807 48.854  1.00 64.47  ? 25  ASN F CG   1 
ATOM   8753  O  OD1  . ASN F 2 25  ? 90.670  -44.726 50.065  1.00 63.41  ? 25  ASN F OD1  1 
ATOM   8754  N  ND2  . ASN F 2 25  ? 90.968  -43.742 48.080  1.00 56.19  ? 25  ASN F ND2  1 
ATOM   8755  N  N    . VAL F 2 26  ? 89.785  -48.574 46.435  1.00 55.71  ? 26  VAL F N    1 
ATOM   8756  C  CA   . VAL F 2 26  ? 89.932  -49.936 45.858  1.00 55.26  ? 26  VAL F CA   1 
ATOM   8757  C  C    . VAL F 2 26  ? 89.680  -49.816 44.359  1.00 53.18  ? 26  VAL F C    1 
ATOM   8758  O  O    . VAL F 2 26  ? 90.432  -50.424 43.601  1.00 52.61  ? 26  VAL F O    1 
ATOM   8759  C  CB   . VAL F 2 26  ? 88.987  -50.938 46.545  1.00 50.98  ? 26  VAL F CB   1 
ATOM   8760  C  CG1  . VAL F 2 26  ? 89.083  -52.333 45.955  1.00 47.44  ? 26  VAL F CG1  1 
ATOM   8761  C  CG2  . VAL F 2 26  ? 89.223  -50.978 48.039  1.00 49.99  ? 26  VAL F CG2  1 
ATOM   8762  N  N    . LYS F 2 27  ? 88.705  -49.003 43.955  1.00 52.77  ? 27  LYS F N    1 
ATOM   8763  C  CA   . LYS F 2 27  ? 88.527  -48.852 42.519  1.00 52.20  ? 27  LYS F CA   1 
ATOM   8764  C  C    . LYS F 2 27  ? 89.746  -48.182 41.903  1.00 54.66  ? 27  LYS F C    1 
ATOM   8765  O  O    . LYS F 2 27  ? 90.138  -48.502 40.773  1.00 53.78  ? 27  LYS F O    1 
ATOM   8766  C  CB   . LYS F 2 27  ? 87.261  -48.052 42.214  1.00 53.62  ? 27  LYS F CB   1 
ATOM   8767  C  CG   . LYS F 2 27  ? 85.944  -48.804 42.403  1.00 55.67  ? 27  LYS F CG   1 
ATOM   8768  C  CD   . LYS F 2 27  ? 84.775  -47.815 42.323  1.00 52.57  ? 27  LYS F CD   1 
ATOM   8769  C  CE   . LYS F 2 27  ? 83.415  -48.500 42.467  1.00 54.68  ? 27  LYS F CE   1 
ATOM   8770  N  NZ   . LYS F 2 27  ? 82.249  -47.538 42.492  1.00 49.48  ? 27  LYS F NZ   1 
ATOM   8771  N  N    . ALA F 2 28  ? 90.360  -47.250 42.641  1.00 51.18  ? 28  ALA F N    1 
ATOM   8772  C  CA   . ALA F 2 28  ? 91.571  -46.595 42.163  1.00 54.87  ? 28  ALA F CA   1 
ATOM   8773  C  C    . ALA F 2 28  ? 92.686  -47.603 41.966  1.00 53.95  ? 28  ALA F C    1 
ATOM   8774  O  O    . ALA F 2 28  ? 93.433  -47.544 40.978  1.00 54.27  ? 28  ALA F O    1 
ATOM   8775  C  CB   . ALA F 2 28  ? 92.013  -45.510 43.150  1.00 50.93  ? 28  ALA F CB   1 
ATOM   8776  N  N    . LYS F 2 29  ? 92.811  -48.539 42.900  1.00 53.30  ? 29  LYS F N    1 
ATOM   8777  C  CA   . LYS F 2 29  ? 93.838  -49.559 42.793  1.00 52.31  ? 29  LYS F CA   1 
ATOM   8778  C  C    . LYS F 2 29  ? 93.545  -50.553 41.681  1.00 51.26  ? 29  LYS F C    1 
ATOM   8779  O  O    . LYS F 2 29  ? 94.480  -51.138 41.132  1.00 50.39  ? 29  LYS F O    1 
ATOM   8780  C  CB   . LYS F 2 29  ? 93.991  -50.256 44.140  1.00 50.69  ? 29  LYS F CB   1 
ATOM   8781  C  CG   . LYS F 2 29  ? 94.739  -49.388 45.136  1.00 48.68  ? 29  LYS F CG   1 
ATOM   8782  C  CD   . LYS F 2 29  ? 94.345  -49.731 46.550  1.00 56.53  ? 29  LYS F CD   1 
ATOM   8783  C  CE   . LYS F 2 29  ? 95.377  -49.213 47.522  1.00 54.29  ? 29  LYS F CE   1 
ATOM   8784  N  NZ   . LYS F 2 29  ? 94.810  -49.287 48.895  1.00 64.05  ? 29  LYS F NZ   1 
ATOM   8785  N  N    . ILE F 2 30  ? 92.278  -50.721 41.301  1.00 53.96  ? 30  ILE F N    1 
ATOM   8786  C  CA   . ILE F 2 30  ? 91.953  -51.622 40.198  1.00 54.20  ? 30  ILE F CA   1 
ATOM   8787  C  C    . ILE F 2 30  ? 92.329  -50.976 38.870  1.00 53.24  ? 30  ILE F C    1 
ATOM   8788  O  O    . ILE F 2 30  ? 92.947  -51.613 38.009  1.00 52.75  ? 30  ILE F O    1 
ATOM   8789  C  CB   . ILE F 2 30  ? 90.466  -52.033 40.264  1.00 46.96  ? 30  ILE F CB   1 
ATOM   8790  C  CG1  . ILE F 2 30  ? 90.255  -52.984 41.440  1.00 47.79  ? 30  ILE F CG1  1 
ATOM   8791  C  CG2  . ILE F 2 30  ? 90.028  -52.701 39.008  1.00 48.10  ? 30  ILE F CG2  1 
ATOM   8792  C  CD1  . ILE F 2 30  ? 88.789  -53.398 41.678  1.00 42.39  ? 30  ILE F CD1  1 
ATOM   8793  N  N    . GLN F 2 31  ? 92.001  -49.687 38.701  1.00 54.02  ? 31  GLN F N    1 
ATOM   8794  C  CA   . GLN F 2 31  ? 92.444  -48.957 37.509  1.00 57.23  ? 31  GLN F CA   1 
ATOM   8795  C  C    . GLN F 2 31  ? 93.961  -49.019 37.359  1.00 52.50  ? 31  GLN F C    1 
ATOM   8796  O  O    . GLN F 2 31  ? 94.478  -49.131 36.247  1.00 55.12  ? 31  GLN F O    1 
ATOM   8797  C  CB   . GLN F 2 31  ? 91.970  -47.495 37.556  1.00 54.37  ? 31  GLN F CB   1 
ATOM   8798  C  CG   . GLN F 2 31  ? 92.589  -46.563 36.447  1.00 56.40  ? 31  GLN F CG   1 
ATOM   8799  C  CD   . GLN F 2 31  ? 92.069  -45.106 36.509  1.00 54.92  ? 31  GLN F CD   1 
ATOM   8800  O  OE1  . GLN F 2 31  ? 92.041  -44.477 37.571  1.00 55.64  ? 31  GLN F OE1  1 
ATOM   8801  N  NE2  . GLN F 2 31  ? 91.638  -44.589 35.373  1.00 54.24  ? 31  GLN F NE2  1 
ATOM   8802  N  N    . ASP F 2 32  ? 94.706  -49.015 38.455  1.00 56.49  ? 32  ASP F N    1 
ATOM   8803  C  CA   . ASP F 2 32  ? 96.183  -49.132 38.360  1.00 51.23  ? 32  ASP F CA   1 
ATOM   8804  C  C    . ASP F 2 32  ? 96.584  -50.457 37.725  1.00 54.17  ? 32  ASP F C    1 
ATOM   8805  O  O    . ASP F 2 32  ? 97.333  -50.423 36.748  1.00 58.92  ? 32  ASP F O    1 
ATOM   8806  C  CB   . ASP F 2 32  ? 96.846  -49.011 39.726  1.00 50.64  ? 32  ASP F CB   1 
ATOM   8807  C  CG   . ASP F 2 32  ? 98.353  -49.170 39.718  1.00 56.34  ? 32  ASP F CG   1 
ATOM   8808  O  OD1  . ASP F 2 32  ? 99.028  -48.299 39.149  1.00 54.93  ? 32  ASP F OD1  1 
ATOM   8809  O  OD2  . ASP F 2 32  ? 98.832  -50.156 40.299  1.00 53.11  ? 32  ASP F OD2  1 
ATOM   8810  N  N    . LYS F 2 33  ? 96.101  -51.572 38.257  1.00 58.60  ? 33  LYS F N    1 
ATOM   8811  C  CA   . LYS F 2 33  ? 96.543  -52.902 37.770  1.00 54.19  ? 33  LYS F CA   1 
ATOM   8812  C  C    . LYS F 2 33  ? 95.757  -53.347 36.539  1.00 53.73  ? 33  LYS F C    1 
ATOM   8813  O  O    . LYS F 2 33  ? 96.322  -54.106 35.745  1.00 54.85  ? 33  LYS F O    1 
ATOM   8814  C  CB   . LYS F 2 33  ? 96.374  -53.922 38.895  1.00 46.36  ? 33  LYS F CB   1 
ATOM   8815  C  CG   . LYS F 2 33  ? 97.550  -54.849 39.140  1.00 52.84  ? 33  LYS F CG   1 
ATOM   8816  C  CD   . LYS F 2 33  ? 97.203  -55.924 40.132  1.00 49.25  ? 33  LYS F CD   1 
ATOM   8817  C  CE   . LYS F 2 33  ? 98.402  -56.738 40.554  1.00 49.49  ? 33  LYS F CE   1 
ATOM   8818  N  NZ   . LYS F 2 33  ? 98.710  -56.565 41.992  1.00 53.20  ? 33  LYS F NZ   1 
ATOM   8819  N  N    . GLU F 2 34  ? 94.525  -52.874 36.367  1.00 54.16  ? 34  GLU F N    1 
ATOM   8820  C  CA   . GLU F 2 34  ? 93.739  -53.412 35.268  1.00 55.26  ? 34  GLU F CA   1 
ATOM   8821  C  C    . GLU F 2 34  ? 93.300  -52.386 34.236  1.00 58.23  ? 34  GLU F C    1 
ATOM   8822  O  O    . GLU F 2 34  ? 92.719  -52.778 33.212  1.00 60.65  ? 34  GLU F O    1 
ATOM   8823  C  CB   . GLU F 2 34  ? 92.486  -54.118 35.805  1.00 53.61  ? 34  GLU F CB   1 
ATOM   8824  C  CG   . GLU F 2 34  ? 92.715  -55.560 36.137  1.00 60.69  ? 34  GLU F CG   1 
ATOM   8825  C  CD   . GLU F 2 34  ? 92.443  -56.482 34.973  1.00 62.16  ? 34  GLU F CD   1 
ATOM   8826  O  OE1  . GLU F 2 34  ? 91.342  -56.392 34.374  1.00 61.34  ? 34  GLU F OE1  1 
ATOM   8827  O  OE2  . GLU F 2 34  ? 93.334  -57.307 34.676  1.00 65.40  ? 34  GLU F OE2  1 
ATOM   8828  N  N    . GLY F 2 35  ? 93.457  -51.098 34.504  1.00 56.23  ? 35  GLY F N    1 
ATOM   8829  C  CA   . GLY F 2 35  ? 93.137  -50.080 33.485  1.00 48.63  ? 35  GLY F CA   1 
ATOM   8830  C  C    . GLY F 2 35  ? 91.669  -49.723 33.376  1.00 51.60  ? 35  GLY F C    1 
ATOM   8831  O  O    . GLY F 2 35  ? 91.340  -48.920 32.506  1.00 57.25  ? 35  GLY F O    1 
ATOM   8832  N  N    . ILE F 2 36  ? 90.817  -50.303 34.211  1.00 53.81  ? 36  ILE F N    1 
ATOM   8833  C  CA   . ILE F 2 36  ? 89.352  -50.052 34.112  1.00 52.48  ? 36  ILE F CA   1 
ATOM   8834  C  C    . ILE F 2 36  ? 89.045  -48.746 34.835  1.00 55.72  ? 36  ILE F C    1 
ATOM   8835  O  O    . ILE F 2 36  ? 89.339  -48.650 36.012  1.00 56.76  ? 36  ILE F O    1 
ATOM   8836  C  CB   . ILE F 2 36  ? 88.542  -51.221 34.693  1.00 57.96  ? 36  ILE F CB   1 
ATOM   8837  C  CG1  . ILE F 2 36  ? 89.168  -52.570 34.335  1.00 59.62  ? 36  ILE F CG1  1 
ATOM   8838  C  CG2  . ILE F 2 36  ? 87.086  -51.128 34.266  1.00 57.58  ? 36  ILE F CG2  1 
ATOM   8839  C  CD1  . ILE F 2 36  ? 88.196  -53.587 33.803  1.00 58.33  ? 36  ILE F CD1  1 
ATOM   8840  N  N    . PRO F 2 37  ? 88.487  -47.730 34.159  1.00 58.23  ? 37  PRO F N    1 
ATOM   8841  C  CA   . PRO F 2 37  ? 88.226  -46.459 34.810  1.00 59.36  ? 37  PRO F CA   1 
ATOM   8842  C  C    . PRO F 2 37  ? 87.250  -46.626 35.987  1.00 58.35  ? 37  PRO F C    1 
ATOM   8843  O  O    . PRO F 2 37  ? 86.291  -47.341 35.826  1.00 55.75  ? 37  PRO F O    1 
ATOM   8844  C  CB   . PRO F 2 37  ? 87.606  -45.651 33.666  1.00 59.23  ? 37  PRO F CB   1 
ATOM   8845  C  CG   . PRO F 2 37  ? 88.151  -46.282 32.418  1.00 54.42  ? 37  PRO F CG   1 
ATOM   8846  C  CD   . PRO F 2 37  ? 88.119  -47.753 32.747  1.00 49.54  ? 37  PRO F CD   1 
ATOM   8847  N  N    . PRO F 2 38  ? 87.484  -46.016 37.175  1.00 56.92  ? 38  PRO F N    1 
ATOM   8848  C  CA   . PRO F 2 38  ? 86.591  -46.228 38.334  1.00 56.08  ? 38  PRO F CA   1 
ATOM   8849  C  C    . PRO F 2 38  ? 85.114  -46.016 38.044  1.00 59.68  ? 38  PRO F C    1 
ATOM   8850  O  O    . PRO F 2 38  ? 84.276  -46.770 38.560  1.00 58.98  ? 38  PRO F O    1 
ATOM   8851  C  CB   . PRO F 2 38  ? 87.110  -45.209 39.356  1.00 54.19  ? 38  PRO F CB   1 
ATOM   8852  C  CG   . PRO F 2 38  ? 88.566  -45.077 39.026  1.00 55.25  ? 38  PRO F CG   1 
ATOM   8853  C  CD   . PRO F 2 38  ? 88.653  -45.192 37.514  1.00 57.45  ? 38  PRO F CD   1 
ATOM   8854  N  N    . ASP F 2 39  ? 84.766  -45.006 37.239  1.00 61.04  ? 39  ASP F N    1 
ATOM   8855  C  CA   . ASP F 2 39  ? 83.366  -44.767 36.905  1.00 63.23  ? 39  ASP F CA   1 
ATOM   8856  C  C    . ASP F 2 39  ? 82.681  -46.032 36.414  1.00 61.71  ? 39  ASP F C    1 
ATOM   8857  O  O    . ASP F 2 39  ? 81.482  -46.222 36.645  1.00 57.88  ? 39  ASP F O    1 
ATOM   8858  C  CB   . ASP F 2 39  ? 83.245  -43.677 35.832  1.00 58.16  ? 39  ASP F CB   1 
ATOM   8859  C  CG   . ASP F 2 39  ? 83.505  -42.315 36.375  1.00 76.96  ? 39  ASP F CG   1 
ATOM   8860  O  OD1  . ASP F 2 39  ? 83.778  -42.228 37.597  1.00 73.46  ? 39  ASP F OD1  1 
ATOM   8861  O  OD2  . ASP F 2 39  ? 83.423  -41.336 35.593  1.00 85.75  ? 39  ASP F OD2  1 
ATOM   8862  N  N    . GLN F 2 40  ? 83.413  -46.898 35.729  1.00 58.33  ? 40  GLN F N    1 
ATOM   8863  C  CA   . GLN F 2 40  ? 82.766  -48.059 35.072  1.00 57.79  ? 40  GLN F CA   1 
ATOM   8864  C  C    . GLN F 2 40  ? 82.777  -49.325 35.922  1.00 52.88  ? 40  GLN F C    1 
ATOM   8865  O  O    . GLN F 2 40  ? 82.097  -50.276 35.538  1.00 54.56  ? 40  GLN F O    1 
ATOM   8866  C  CB   . GLN F 2 40  ? 83.522  -48.343 33.776  1.00 53.71  ? 40  GLN F CB   1 
ATOM   8867  C  CG   . GLN F 2 40  ? 83.439  -47.236 32.739  1.00 58.69  ? 40  GLN F CG   1 
ATOM   8868  C  CD   . GLN F 2 40  ? 83.782  -47.750 31.363  1.00 70.88  ? 40  GLN F CD   1 
ATOM   8869  O  OE1  . GLN F 2 40  ? 83.211  -48.726 30.880  1.00 71.81  ? 40  GLN F OE1  1 
ATOM   8870  N  NE2  . GLN F 2 40  ? 84.729  -47.093 30.717  1.00 63.42  ? 40  GLN F NE2  1 
ATOM   8871  N  N    . GLN F 2 41  ? 83.447  -49.319 37.059  1.00 51.78  ? 41  GLN F N    1 
ATOM   8872  C  CA   . GLN F 2 41  ? 83.610  -50.556 37.802  1.00 56.36  ? 41  GLN F CA   1 
ATOM   8873  C  C    . GLN F 2 41  ? 82.471  -50.749 38.792  1.00 57.33  ? 41  GLN F C    1 
ATOM   8874  O  O    . GLN F 2 41  ? 82.099  -49.817 39.527  1.00 54.48  ? 41  GLN F O    1 
ATOM   8875  C  CB   . GLN F 2 41  ? 84.932  -50.577 38.565  1.00 55.30  ? 41  GLN F CB   1 
ATOM   8876  C  CG   . GLN F 2 41  ? 86.124  -50.107 37.821  1.00 55.90  ? 41  GLN F CG   1 
ATOM   8877  C  CD   . GLN F 2 41  ? 87.317  -50.110 38.726  1.00 54.68  ? 41  GLN F CD   1 
ATOM   8878  O  OE1  . GLN F 2 41  ? 87.261  -50.693 39.812  1.00 50.83  ? 41  GLN F OE1  1 
ATOM   8879  N  NE2  . GLN F 2 41  ? 88.395  -49.449 38.311  1.00 51.42  ? 41  GLN F NE2  1 
ATOM   8880  N  N    . ARG F 2 42  ? 82.022  -52.001 38.853  1.00 51.14  ? 42  ARG F N    1 
ATOM   8881  C  CA   . ARG F 2 42  ? 81.040  -52.409 39.876  1.00 52.38  ? 42  ARG F CA   1 
ATOM   8882  C  C    . ARG F 2 42  ? 81.676  -53.609 40.586  1.00 49.91  ? 42  ARG F C    1 
ATOM   8883  O  O    . ARG F 2 42  ? 82.186  -54.489 39.888  1.00 51.00  ? 42  ARG F O    1 
ATOM   8884  C  CB   . ARG F 2 42  ? 79.688  -52.708 39.236  1.00 50.20  ? 42  ARG F CB   1 
ATOM   8885  C  CG   . ARG F 2 42  ? 79.070  -51.557 38.458  1.00 52.37  ? 42  ARG F CG   1 
ATOM   8886  C  CD   . ARG F 2 42  ? 77.884  -52.052 37.661  1.00 53.01  ? 42  ARG F CD   1 
ATOM   8887  N  NE   . ARG F 2 42  ? 77.159  -53.037 38.438  1.00 60.37  ? 42  ARG F NE   1 
ATOM   8888  C  CZ   . ARG F 2 42  ? 76.558  -54.115 37.965  1.00 56.36  ? 42  ARG F CZ   1 
ATOM   8889  N  NH1  . ARG F 2 42  ? 76.552  -54.378 36.673  1.00 58.17  ? 42  ARG F NH1  1 
ATOM   8890  N  NH2  . ARG F 2 42  ? 75.958  -54.931 38.805  1.00 61.85  ? 42  ARG F NH2  1 
ATOM   8891  N  N    . LEU F 2 43  ? 81.688  -53.624 41.912  1.00 43.59  ? 43  LEU F N    1 
ATOM   8892  C  CA   . LEU F 2 43  ? 82.319  -54.662 42.720  1.00 47.79  ? 43  LEU F CA   1 
ATOM   8893  C  C    . LEU F 2 43  ? 81.243  -55.401 43.503  1.00 52.55  ? 43  LEU F C    1 
ATOM   8894  O  O    . LEU F 2 43  ? 80.507  -54.786 44.283  1.00 48.75  ? 43  LEU F O    1 
ATOM   8895  C  CB   . LEU F 2 43  ? 83.351  -54.058 43.672  1.00 39.78  ? 43  LEU F CB   1 
ATOM   8896  C  CG   . LEU F 2 43  ? 84.622  -53.595 42.947  1.00 49.19  ? 43  LEU F CG   1 
ATOM   8897  C  CD1  . LEU F 2 43  ? 85.522  -52.718 43.817  1.00 45.65  ? 43  LEU F CD1  1 
ATOM   8898  C  CD2  . LEU F 2 43  ? 85.396  -54.820 42.413  1.00 49.01  ? 43  LEU F CD2  1 
ATOM   8899  N  N    . ILE F 2 44  ? 81.156  -56.716 43.309  1.00 49.30  ? 44  ILE F N    1 
ATOM   8900  C  CA   . ILE F 2 44  ? 80.185  -57.544 44.017  1.00 48.20  ? 44  ILE F CA   1 
ATOM   8901  C  C    . ILE F 2 44  ? 80.930  -58.422 45.017  1.00 55.00  ? 44  ILE F C    1 
ATOM   8902  O  O    . ILE F 2 44  ? 81.935  -59.061 44.670  1.00 50.26  ? 44  ILE F O    1 
ATOM   8903  C  CB   . ILE F 2 44  ? 79.336  -58.405 43.061  1.00 51.73  ? 44  ILE F CB   1 
ATOM   8904  C  CG1  . ILE F 2 44  ? 78.843  -57.600 41.850  1.00 47.29  ? 44  ILE F CG1  1 
ATOM   8905  C  CG2  . ILE F 2 44  ? 78.143  -58.997 43.807  1.00 51.41  ? 44  ILE F CG2  1 
ATOM   8906  C  CD1  . ILE F 2 44  ? 77.826  -56.536 42.198  1.00 49.31  ? 44  ILE F CD1  1 
ATOM   8907  N  N    . PHE F 2 45  ? 80.430  -58.448 46.257  1.00 52.66  ? 45  PHE F N    1 
ATOM   8908  C  CA   . PHE F 2 45  ? 80.951  -59.298 47.324  1.00 49.89  ? 45  PHE F CA   1 
ATOM   8909  C  C    . PHE F 2 45  ? 79.773  -59.861 48.104  1.00 48.76  ? 45  PHE F C    1 
ATOM   8910  O  O    . PHE F 2 45  ? 79.036  -59.094 48.727  1.00 52.28  ? 45  PHE F O    1 
ATOM   8911  C  CB   . PHE F 2 45  ? 81.864  -58.497 48.265  1.00 50.33  ? 45  PHE F CB   1 
ATOM   8912  C  CG   . PHE F 2 45  ? 82.436  -59.309 49.382  1.00 45.89  ? 45  PHE F CG   1 
ATOM   8913  C  CD1  . PHE F 2 45  ? 83.344  -60.322 49.119  1.00 46.37  ? 45  PHE F CD1  1 
ATOM   8914  C  CD2  . PHE F 2 45  ? 82.054  -59.079 50.684  1.00 44.95  ? 45  PHE F CD2  1 
ATOM   8915  C  CE1  . PHE F 2 45  ? 83.877  -61.095 50.159  1.00 53.60  ? 45  PHE F CE1  1 
ATOM   8916  C  CE2  . PHE F 2 45  ? 82.568  -59.849 51.720  1.00 46.77  ? 45  PHE F CE2  1 
ATOM   8917  C  CZ   . PHE F 2 45  ? 83.486  -60.857 51.454  1.00 49.56  ? 45  PHE F CZ   1 
ATOM   8918  N  N    . ALA F 2 46  ? 79.586  -61.184 48.071  1.00 48.82  ? 46  ALA F N    1 
ATOM   8919  C  CA   . ALA F 2 46  ? 78.579  -61.860 48.907  1.00 49.56  ? 46  ALA F CA   1 
ATOM   8920  C  C    . ALA F 2 46  ? 77.172  -61.300 48.696  1.00 50.36  ? 46  ALA F C    1 
ATOM   8921  O  O    . ALA F 2 46  ? 76.399  -61.125 49.650  1.00 46.76  ? 46  ALA F O    1 
ATOM   8922  C  CB   . ALA F 2 46  ? 78.955  -61.793 50.398  1.00 39.24  ? 46  ALA F CB   1 
ATOM   8923  N  N    . GLY F 2 47  ? 76.837  -61.010 47.447  1.00 43.80  ? 47  GLY F N    1 
ATOM   8924  C  CA   . GLY F 2 47  ? 75.552  -60.449 47.107  1.00 47.62  ? 47  GLY F CA   1 
ATOM   8925  C  C    . GLY F 2 47  ? 75.526  -58.938 47.049  1.00 52.55  ? 47  GLY F C    1 
ATOM   8926  O  O    . GLY F 2 47  ? 74.730  -58.370 46.301  1.00 51.87  ? 47  GLY F O    1 
ATOM   8927  N  N    . LYS F 2 48  ? 76.387  -58.273 47.811  1.00 51.53  ? 48  LYS F N    1 
ATOM   8928  C  CA   . LYS F 2 48  ? 76.357  -56.821 47.892  1.00 54.82  ? 48  LYS F CA   1 
ATOM   8929  C  C    . LYS F 2 48  ? 77.200  -56.199 46.787  1.00 53.88  ? 48  LYS F C    1 
ATOM   8930  O  O    . LYS F 2 48  ? 78.292  -56.686 46.481  1.00 51.93  ? 48  LYS F O    1 
ATOM   8931  C  CB   . LYS F 2 48  ? 76.861  -56.355 49.261  1.00 52.49  ? 48  LYS F CB   1 
ATOM   8932  C  CG   . LYS F 2 48  ? 76.183  -57.022 50.430  1.00 47.74  ? 48  LYS F CG   1 
ATOM   8933  N  N    . GLN F 2 49  ? 76.677  -55.131 46.179  1.00 54.49  ? 49  GLN F N    1 
ATOM   8934  C  CA   . GLN F 2 49  ? 77.486  -54.239 45.355  1.00 53.48  ? 49  GLN F CA   1 
ATOM   8935  C  C    . GLN F 2 49  ? 78.100  -53.193 46.278  1.00 54.39  ? 49  GLN F C    1 
ATOM   8936  O  O    . GLN F 2 49  ? 77.378  -52.517 47.021  1.00 56.91  ? 49  GLN F O    1 
ATOM   8937  C  CB   . GLN F 2 49  ? 76.670  -53.573 44.241  1.00 52.19  ? 49  GLN F CB   1 
ATOM   8938  C  CG   . GLN F 2 49  ? 77.551  -52.831 43.200  1.00 55.17  ? 49  GLN F CG   1 
ATOM   8939  C  CD   . GLN F 2 49  ? 76.789  -52.355 41.949  1.00 59.55  ? 49  GLN F CD   1 
ATOM   8940  O  OE1  . GLN F 2 49  ? 76.347  -53.153 41.114  1.00 57.14  ? 49  GLN F OE1  1 
ATOM   8941  N  NE2  . GLN F 2 49  ? 76.662  -51.036 41.811  1.00 56.85  ? 49  GLN F NE2  1 
ATOM   8942  N  N    . LEU F 2 50  ? 79.429  -53.094 46.269  1.00 47.02  ? 50  LEU F N    1 
ATOM   8943  C  CA   . LEU F 2 50  ? 80.119  -52.215 47.204  1.00 52.17  ? 50  LEU F CA   1 
ATOM   8944  C  C    . LEU F 2 50  ? 79.910  -50.749 46.816  1.00 52.79  ? 50  LEU F C    1 
ATOM   8945  O  O    . LEU F 2 50  ? 80.016  -50.380 45.643  1.00 49.28  ? 50  LEU F O    1 
ATOM   8946  C  CB   . LEU F 2 50  ? 81.612  -52.570 47.245  1.00 54.54  ? 50  LEU F CB   1 
ATOM   8947  C  CG   . LEU F 2 50  ? 81.966  -54.050 47.543  1.00 49.65  ? 50  LEU F CG   1 
ATOM   8948  C  CD1  . LEU F 2 50  ? 83.451  -54.240 47.706  1.00 45.67  ? 50  LEU F CD1  1 
ATOM   8949  C  CD2  . LEU F 2 50  ? 81.270  -54.565 48.779  1.00 46.23  ? 50  LEU F CD2  1 
ATOM   8950  N  N    . GLU F 2 51  ? 79.594  -49.907 47.798  1.00 55.09  ? 51  GLU F N    1 
ATOM   8951  C  CA   . GLU F 2 51  ? 79.202  -48.526 47.527  1.00 56.96  ? 51  GLU F CA   1 
ATOM   8952  C  C    . GLU F 2 51  ? 80.338  -47.556 47.798  1.00 51.77  ? 51  GLU F C    1 
ATOM   8953  O  O    . GLU F 2 51  ? 81.087  -47.717 48.762  1.00 53.46  ? 51  GLU F O    1 
ATOM   8954  C  CB   . GLU F 2 51  ? 78.016  -48.116 48.385  1.00 56.22  ? 51  GLU F CB   1 
ATOM   8955  C  CG   . GLU F 2 51  ? 76.938  -49.134 48.435  1.00 58.22  ? 51  GLU F CG   1 
ATOM   8956  C  CD   . GLU F 2 51  ? 75.829  -48.734 49.382  1.00 65.53  ? 51  GLU F CD   1 
ATOM   8957  O  OE1  . GLU F 2 51  ? 75.683  -49.404 50.434  1.00 63.84  ? 51  GLU F OE1  1 
ATOM   8958  O  OE2  . GLU F 2 51  ? 75.110  -47.749 49.065  1.00 73.00  ? 51  GLU F OE2  1 
ATOM   8959  N  N    . ASP F 2 52  ? 80.431  -46.524 46.970  1.00 51.91  ? 52  ASP F N    1 
ATOM   8960  C  CA   . ASP F 2 52  ? 81.374  -45.444 47.242  1.00 55.24  ? 52  ASP F CA   1 
ATOM   8961  C  C    . ASP F 2 52  ? 81.009  -44.758 48.554  1.00 58.56  ? 52  ASP F C    1 
ATOM   8962  O  O    . ASP F 2 52  ? 79.861  -44.356 48.769  1.00 62.42  ? 52  ASP F O    1 
ATOM   8963  C  CB   . ASP F 2 52  ? 81.388  -44.432 46.086  1.00 49.05  ? 52  ASP F CB   1 
ATOM   8964  C  CG   . ASP F 2 52  ? 82.064  -44.989 44.828  1.00 56.11  ? 52  ASP F CG   1 
ATOM   8965  O  OD1  . ASP F 2 52  ? 82.747  -46.029 44.929  1.00 55.36  ? 52  ASP F OD1  1 
ATOM   8966  O  OD2  . ASP F 2 52  ? 81.916  -44.402 43.738  1.00 59.41  ? 52  ASP F OD2  1 
ATOM   8967  N  N    . GLY F 2 53  ? 81.987  -44.644 49.447  1.00 55.50  ? 53  GLY F N    1 
ATOM   8968  C  CA   . GLY F 2 53  ? 81.803  -44.026 50.743  1.00 50.49  ? 53  GLY F CA   1 
ATOM   8969  C  C    . GLY F 2 53  ? 82.140  -44.952 51.889  1.00 59.33  ? 53  GLY F C    1 
ATOM   8970  O  O    . GLY F 2 53  ? 82.629  -44.495 52.926  1.00 69.59  ? 53  GLY F O    1 
ATOM   8971  N  N    . ARG F 2 54  ? 81.883  -46.239 51.724  1.00 60.30  ? 54  ARG F N    1 
ATOM   8972  C  CA   . ARG F 2 54  ? 82.153  -47.191 52.783  1.00 63.01  ? 54  ARG F CA   1 
ATOM   8973  C  C    . ARG F 2 54  ? 83.556  -47.770 52.610  1.00 57.93  ? 54  ARG F C    1 
ATOM   8974  O  O    . ARG F 2 54  ? 84.215  -47.592 51.582  1.00 53.48  ? 54  ARG F O    1 
ATOM   8975  C  CB   . ARG F 2 54  ? 81.086  -48.294 52.798  1.00 66.44  ? 54  ARG F CB   1 
ATOM   8976  C  CG   . ARG F 2 54  ? 79.646  -47.784 52.662  1.00 59.33  ? 54  ARG F CG   1 
ATOM   8977  C  CD   . ARG F 2 54  ? 78.787  -48.210 53.849  1.00 71.41  ? 54  ARG F CD   1 
ATOM   8978  N  NE   . ARG F 2 54  ? 79.320  -47.754 55.142  1.00 78.75  ? 54  ARG F NE   1 
ATOM   8979  C  CZ   . ARG F 2 54  ? 79.327  -46.492 55.584  1.00 79.06  ? 54  ARG F CZ   1 
ATOM   8980  N  NH1  . ARG F 2 54  ? 78.817  -45.503 54.855  1.00 75.66  ? 54  ARG F NH1  1 
ATOM   8981  N  NH2  . ARG F 2 54  ? 79.855  -46.215 56.773  1.00 81.43  ? 54  ARG F NH2  1 
ATOM   8982  N  N    . THR F 2 55  ? 83.976  -48.461 53.668  1.00 56.23  ? 55  THR F N    1 
ATOM   8983  C  CA   . THR F 2 55  ? 85.314  -49.077 53.704  1.00 55.81  ? 55  THR F CA   1 
ATOM   8984  C  C    . THR F 2 55  ? 85.189  -50.587 53.527  1.00 58.70  ? 55  THR F C    1 
ATOM   8985  O  O    . THR F 2 55  ? 84.069  -51.095 53.544  1.00 53.78  ? 55  THR F O    1 
ATOM   8986  C  CB   . THR F 2 55  ? 85.987  -48.757 55.041  1.00 58.99  ? 55  THR F CB   1 
ATOM   8987  O  OG1  . THR F 2 55  ? 85.363  -49.503 56.085  1.00 55.42  ? 55  THR F OG1  1 
ATOM   8988  C  CG2  . THR F 2 55  ? 85.942  -47.285 55.384  1.00 55.54  ? 55  THR F CG2  1 
ATOM   8989  N  N    . LEU F 2 56  ? 86.320  -51.267 53.389  1.00 56.89  ? 56  LEU F N    1 
ATOM   8990  C  CA   . LEU F 2 56  ? 86.316  -52.735 53.209  1.00 51.76  ? 56  LEU F CA   1 
ATOM   8991  C  C    . LEU F 2 56  ? 85.959  -53.392 54.536  1.00 58.85  ? 56  LEU F C    1 
ATOM   8992  O  O    . LEU F 2 56  ? 85.263  -54.407 54.512  1.00 64.09  ? 56  LEU F O    1 
ATOM   8993  C  CB   . LEU F 2 56  ? 87.704  -53.158 52.736  1.00 53.75  ? 56  LEU F CB   1 
ATOM   8994  C  CG   . LEU F 2 56  ? 88.081  -52.709 51.333  1.00 54.33  ? 56  LEU F CG   1 
ATOM   8995  C  CD1  . LEU F 2 56  ? 89.505  -53.120 51.037  1.00 52.23  ? 56  LEU F CD1  1 
ATOM   8996  C  CD2  . LEU F 2 56  ? 87.138  -53.308 50.306  1.00 48.47  ? 56  LEU F CD2  1 
ATOM   8997  N  N    . SER F 2 57  ? 86.423  -52.825 55.644  1.00 61.46  ? 57  SER F N    1 
ATOM   8998  C  CA   . SER F 2 57  ? 86.086  -53.346 56.988  1.00 62.19  ? 57  SER F CA   1 
ATOM   8999  C  C    . SER F 2 57  ? 84.581  -53.232 57.207  1.00 60.81  ? 57  SER F C    1 
ATOM   9000  O  O    . SER F 2 57  ? 84.039  -54.054 57.946  1.00 59.17  ? 57  SER F O    1 
ATOM   9001  C  CB   . SER F 2 57  ? 86.842  -52.602 58.044  1.00 65.29  ? 57  SER F CB   1 
ATOM   9002  O  OG   . SER F 2 57  ? 86.730  -51.200 57.865  1.00 67.79  ? 57  SER F OG   1 
ATOM   9003  N  N    . ASP F 2 58  ? 83.950  -52.240 56.586  1.00 58.43  ? 58  ASP F N    1 
ATOM   9004  C  CA   . ASP F 2 58  ? 82.485  -52.063 56.709  1.00 60.68  ? 58  ASP F CA   1 
ATOM   9005  C  C    . ASP F 2 58  ? 81.784  -53.293 56.131  1.00 59.83  ? 58  ASP F C    1 
ATOM   9006  O  O    . ASP F 2 58  ? 80.731  -53.658 56.657  1.00 57.73  ? 58  ASP F O    1 
ATOM   9007  C  CB   . ASP F 2 58  ? 82.021  -50.762 56.050  1.00 62.55  ? 58  ASP F CB   1 
ATOM   9008  C  CG   . ASP F 2 58  ? 82.185  -49.521 56.908  1.00 66.46  ? 58  ASP F CG   1 
ATOM   9009  O  OD1  . ASP F 2 58  ? 82.323  -49.667 58.134  1.00 64.92  ? 58  ASP F OD1  1 
ATOM   9010  O  OD2  . ASP F 2 58  ? 82.174  -48.417 56.337  1.00 67.03  ? 58  ASP F OD2  1 
ATOM   9011  N  N    . TYR F 2 59  ? 82.367  -53.907 55.103  1.00 56.49  ? 59  TYR F N    1 
ATOM   9012  C  CA   . TYR F 2 59  ? 81.748  -55.089 54.525  1.00 56.20  ? 59  TYR F CA   1 
ATOM   9013  C  C    . TYR F 2 59  ? 82.354  -56.387 55.037  1.00 59.31  ? 59  TYR F C    1 
ATOM   9014  O  O    . TYR F 2 59  ? 82.053  -57.453 54.498  1.00 60.79  ? 59  TYR F O    1 
ATOM   9015  C  CB   . TYR F 2 59  ? 81.883  -55.062 53.014  1.00 53.66  ? 59  TYR F CB   1 
ATOM   9016  C  CG   . TYR F 2 59  ? 81.115  -53.976 52.333  1.00 54.52  ? 59  TYR F CG   1 
ATOM   9017  C  CD1  . TYR F 2 59  ? 79.783  -54.159 51.985  1.00 50.88  ? 59  TYR F CD1  1 
ATOM   9018  C  CD2  . TYR F 2 59  ? 81.727  -52.783 51.993  1.00 51.47  ? 59  TYR F CD2  1 
ATOM   9019  C  CE1  . TYR F 2 59  ? 79.084  -53.177 51.345  1.00 46.31  ? 59  TYR F CE1  1 
ATOM   9020  C  CE2  . TYR F 2 59  ? 81.025  -51.787 51.351  1.00 47.43  ? 59  TYR F CE2  1 
ATOM   9021  C  CZ   . TYR F 2 59  ? 79.706  -51.991 51.027  1.00 44.92  ? 59  TYR F CZ   1 
ATOM   9022  O  OH   . TYR F 2 59  ? 78.994  -51.002 50.384  1.00 48.48  ? 59  TYR F OH   1 
ATOM   9023  N  N    . ASN F 2 60  ? 83.243  -56.316 56.020  1.00 56.27  ? 60  ASN F N    1 
ATOM   9024  C  CA   . ASN F 2 60  ? 83.945  -57.489 56.532  1.00 63.13  ? 60  ASN F CA   1 
ATOM   9025  C  C    . ASN F 2 60  ? 84.802  -58.170 55.463  1.00 58.74  ? 60  ASN F C    1 
ATOM   9026  O  O    . ASN F 2 60  ? 85.016  -59.384 55.497  1.00 59.39  ? 60  ASN F O    1 
ATOM   9027  C  CB   . ASN F 2 60  ? 82.977  -58.496 57.165  1.00 65.09  ? 60  ASN F CB   1 
ATOM   9028  C  CG   . ASN F 2 60  ? 83.648  -59.316 58.241  1.00 73.61  ? 60  ASN F CG   1 
ATOM   9029  O  OD1  . ASN F 2 60  ? 84.097  -58.772 59.259  1.00 79.03  ? 60  ASN F OD1  1 
ATOM   9030  N  ND2  . ASN F 2 60  ? 83.781  -60.620 58.003  1.00 69.60  ? 60  ASN F ND2  1 
ATOM   9031  N  N    . ILE F 2 61  ? 85.312  -57.398 54.515  1.00 61.65  ? 61  ILE F N    1 
ATOM   9032  C  CA   . ILE F 2 61  ? 86.262  -57.914 53.539  1.00 50.62  ? 61  ILE F CA   1 
ATOM   9033  C  C    . ILE F 2 61  ? 87.631  -57.947 54.195  1.00 55.59  ? 61  ILE F C    1 
ATOM   9034  O  O    . ILE F 2 61  ? 88.026  -56.988 54.870  1.00 57.37  ? 61  ILE F O    1 
ATOM   9035  C  CB   . ILE F 2 61  ? 86.254  -57.047 52.272  1.00 53.21  ? 61  ILE F CB   1 
ATOM   9036  C  CG1  . ILE F 2 61  ? 84.942  -57.250 51.510  1.00 54.20  ? 61  ILE F CG1  1 
ATOM   9037  C  CG2  . ILE F 2 61  ? 87.447  -57.375 51.359  1.00 53.73  ? 61  ILE F CG2  1 
ATOM   9038  C  CD1  . ILE F 2 61  ? 84.604  -56.127 50.523  1.00 49.07  ? 61  ILE F CD1  1 
ATOM   9039  N  N    . GLN F 2 62  ? 88.295  -59.089 54.076  1.00 54.15  ? 62  GLN F N    1 
ATOM   9040  C  CA   . GLN F 2 62  ? 89.618  -59.252 54.706  1.00 58.04  ? 62  GLN F CA   1 
ATOM   9041  C  C    . GLN F 2 62  ? 90.589  -59.911 53.736  1.00 57.43  ? 62  GLN F C    1 
ATOM   9042  O  O    . GLN F 2 62  ? 90.267  -60.028 52.558  1.00 55.41  ? 62  GLN F O    1 
ATOM   9043  C  CB   . GLN F 2 62  ? 89.501  -60.094 55.975  1.00 52.23  ? 62  GLN F CB   1 
ATOM   9044  C  CG   . GLN F 2 62  ? 88.725  -61.388 55.813  1.00 57.88  ? 62  GLN F CG   1 
ATOM   9045  C  CD   . GLN F 2 62  ? 88.299  -61.901 57.165  1.00 73.81  ? 62  GLN F CD   1 
ATOM   9046  O  OE1  . GLN F 2 62  ? 87.599  -61.223 57.914  1.00 76.27  ? 62  GLN F OE1  1 
ATOM   9047  N  NE2  . GLN F 2 62  ? 88.735  -63.104 57.496  1.00 71.49  ? 62  GLN F NE2  1 
ATOM   9048  N  N    . LYS F 2 63  ? 91.767  -60.270 54.224  1.00 54.16  ? 63  LYS F N    1 
ATOM   9049  C  CA   . LYS F 2 63  ? 92.736  -60.999 53.429  1.00 53.61  ? 63  LYS F CA   1 
ATOM   9050  C  C    . LYS F 2 63  ? 92.087  -62.254 52.850  1.00 60.72  ? 63  LYS F C    1 
ATOM   9051  O  O    . LYS F 2 63  ? 91.382  -62.986 53.558  1.00 59.09  ? 63  LYS F O    1 
ATOM   9052  C  CB   . LYS F 2 63  ? 93.941  -61.370 54.293  1.00 56.60  ? 63  LYS F CB   1 
ATOM   9053  C  CG   . LYS F 2 63  ? 95.082  -62.014 53.504  1.00 64.69  ? 63  LYS F CG   1 
ATOM   9054  C  CD   . LYS F 2 63  ? 96.035  -62.810 54.413  1.00 65.40  ? 63  LYS F CD   1 
ATOM   9055  C  CE   . LYS F 2 63  ? 97.281  -63.247 53.659  1.00 52.12  ? 63  LYS F CE   1 
ATOM   9056  N  NZ   . LYS F 2 63  ? 96.949  -63.739 52.300  1.00 51.57  ? 63  LYS F NZ   1 
ATOM   9057  N  N    . GLU F 2 64  ? 92.309  -62.485 51.556  1.00 59.08  ? 64  GLU F N    1 
ATOM   9058  C  CA   . GLU F 2 64  ? 91.862  -63.643 50.775  1.00 55.90  ? 64  GLU F CA   1 
ATOM   9059  C  C    . GLU F 2 64  ? 90.390  -63.543 50.403  1.00 58.67  ? 64  GLU F C    1 
ATOM   9060  O  O    . GLU F 2 64  ? 89.868  -64.487 49.772  1.00 55.23  ? 64  GLU F O    1 
ATOM   9061  C  CB   . GLU F 2 64  ? 92.123  -64.992 51.473  1.00 52.16  ? 64  GLU F CB   1 
ATOM   9062  C  CG   . GLU F 2 64  ? 93.594  -65.334 51.527  1.00 54.37  ? 64  GLU F CG   1 
ATOM   9063  C  CD   . GLU F 2 64  ? 93.954  -66.357 52.581  1.00 61.28  ? 64  GLU F CD   1 
ATOM   9064  O  OE1  . GLU F 2 64  ? 93.085  -67.161 52.983  1.00 65.71  ? 64  GLU F OE1  1 
ATOM   9065  O  OE2  . GLU F 2 64  ? 95.126  -66.356 53.008  1.00 61.89  ? 64  GLU F OE2  1 
ATOM   9066  N  N    . SER F 2 65  ? 89.779  -62.395 50.679  1.00 55.00  ? 65  SER F N    1 
ATOM   9067  C  CA   . SER F 2 65  ? 88.386  -62.173 50.232  1.00 49.53  ? 65  SER F CA   1 
ATOM   9068  C  C    . SER F 2 65  ? 88.387  -61.914 48.730  1.00 50.08  ? 65  SER F C    1 
ATOM   9069  O  O    . SER F 2 65  ? 89.272  -61.202 48.264  1.00 55.13  ? 65  SER F O    1 
ATOM   9070  C  CB   . SER F 2 65  ? 87.739  -61.048 50.984  1.00 54.19  ? 65  SER F CB   1 
ATOM   9071  O  OG   . SER F 2 65  ? 87.641  -61.346 52.366  1.00 52.43  ? 65  SER F OG   1 
ATOM   9072  N  N    . THR F 2 66  ? 87.415  -62.471 48.016  1.00 51.58  ? 66  THR F N    1 
ATOM   9073  C  CA   . THR F 2 66  ? 87.324  -62.302 46.562  1.00 45.57  ? 66  THR F CA   1 
ATOM   9074  C  C    . THR F 2 66  ? 86.222  -61.309 46.196  1.00 49.24  ? 66  THR F C    1 
ATOM   9075  O  O    . THR F 2 66  ? 85.044  -61.541 46.481  1.00 54.41  ? 66  THR F O    1 
ATOM   9076  C  CB   . THR F 2 66  ? 87.062  -63.639 45.864  1.00 38.21  ? 66  THR F CB   1 
ATOM   9077  O  OG1  . THR F 2 66  ? 88.215  -64.465 45.969  1.00 50.23  ? 66  THR F OG1  1 
ATOM   9078  C  CG2  . THR F 2 66  ? 86.767  -63.435 44.415  1.00 45.77  ? 66  THR F CG2  1 
ATOM   9079  N  N    . LEU F 2 67  ? 86.596  -60.240 45.509  1.00 53.76  ? 67  LEU F N    1 
ATOM   9080  C  CA   . LEU F 2 67  ? 85.651  -59.283 44.946  1.00 51.09  ? 67  LEU F CA   1 
ATOM   9081  C  C    . LEU F 2 67  ? 85.446  -59.602 43.472  1.00 54.56  ? 67  LEU F C    1 
ATOM   9082  O  O    . LEU F 2 67  ? 86.376  -60.039 42.778  1.00 56.81  ? 67  LEU F O    1 
ATOM   9083  C  CB   . LEU F 2 67  ? 86.162  -57.847 45.081  1.00 42.93  ? 67  LEU F CB   1 
ATOM   9084  C  CG   . LEU F 2 67  ? 86.043  -57.139 46.431  1.00 52.90  ? 67  LEU F CG   1 
ATOM   9085  C  CD1  . LEU F 2 67  ? 86.279  -58.065 47.589  1.00 46.60  ? 67  LEU F CD1  1 
ATOM   9086  C  CD2  . LEU F 2 67  ? 87.002  -55.957 46.507  1.00 49.69  ? 67  LEU F CD2  1 
ATOM   9087  N  N    . HIS F 2 68  ? 84.214  -59.406 43.013  1.00 49.63  ? 68  HIS F N    1 
ATOM   9088  C  CA   . HIS F 2 68  ? 83.864  -59.752 41.615  1.00 52.59  ? 68  HIS F CA   1 
ATOM   9089  C  C    . HIS F 2 68  ? 83.660  -58.469 40.810  1.00 49.08  ? 68  HIS F C    1 
ATOM   9090  O  O    . HIS F 2 68  ? 82.723  -57.731 41.109  1.00 51.84  ? 68  HIS F O    1 
ATOM   9091  C  CB   . HIS F 2 68  ? 82.660  -60.700 41.615  1.00 46.25  ? 68  HIS F CB   1 
ATOM   9092  C  CG   . HIS F 2 68  ? 82.898  -61.982 42.333  1.00 51.14  ? 68  HIS F CG   1 
ATOM   9093  N  ND1  . HIS F 2 68  ? 83.427  -63.087 41.707  1.00 62.38  ? 68  HIS F ND1  1 
ATOM   9094  C  CD2  . HIS F 2 68  ? 82.677  -62.342 43.613  1.00 51.00  ? 68  HIS F CD2  1 
ATOM   9095  C  CE1  . HIS F 2 68  ? 83.524  -64.073 42.571  1.00 54.41  ? 68  HIS F CE1  1 
ATOM   9096  N  NE2  . HIS F 2 68  ? 83.072  -63.641 43.745  1.00 54.92  ? 68  HIS F NE2  1 
ATOM   9097  N  N    . LEU F 2 69  ? 84.517  -58.238 39.823  1.00 48.88  ? 69  LEU F N    1 
ATOM   9098  C  CA   . LEU F 2 69  ? 84.451  -56.999 39.018  1.00 49.49  ? 69  LEU F CA   1 
ATOM   9099  C  C    . LEU F 2 69  ? 83.543  -57.215 37.823  1.00 52.23  ? 69  LEU F C    1 
ATOM   9100  O  O    . LEU F 2 69  ? 83.747  -58.189 37.098  1.00 56.80  ? 69  LEU F O    1 
ATOM   9101  C  CB   . LEU F 2 69  ? 85.860  -56.635 38.559  1.00 50.52  ? 69  LEU F CB   1 
ATOM   9102  C  CG   . LEU F 2 69  ? 85.986  -55.406 37.665  1.00 61.11  ? 69  LEU F CG   1 
ATOM   9103  C  CD1  . LEU F 2 69  ? 85.522  -54.162 38.397  1.00 55.79  ? 69  LEU F CD1  1 
ATOM   9104  C  CD2  . LEU F 2 69  ? 87.424  -55.241 37.213  1.00 63.10  ? 69  LEU F CD2  1 
ATOM   9105  N  N    . VAL F 2 70  ? 82.576  -56.328 37.659  1.00 52.89  ? 70  VAL F N    1 
ATOM   9106  C  CA   . VAL F 2 70  ? 81.654  -56.402 36.499  1.00 53.12  ? 70  VAL F CA   1 
ATOM   9107  C  C    . VAL F 2 70  ? 81.520  -54.999 35.914  1.00 57.38  ? 70  VAL F C    1 
ATOM   9108  O  O    . VAL F 2 70  ? 81.845  -54.025 36.605  1.00 54.87  ? 70  VAL F O    1 
ATOM   9109  C  CB   . VAL F 2 70  ? 80.283  -56.975 36.889  1.00 54.61  ? 70  VAL F CB   1 
ATOM   9110  C  CG1  . VAL F 2 70  ? 80.358  -58.455 37.182  1.00 51.89  ? 70  VAL F CG1  1 
ATOM   9111  C  CG2  . VAL F 2 70  ? 79.653  -56.238 38.057  1.00 52.30  ? 70  VAL F CG2  1 
ATOM   9112  N  N    . LEU F 2 71  ? 81.055  -54.930 34.677  1.00 55.63  ? 71  LEU F N    1 
ATOM   9113  C  CA   . LEU F 2 71  ? 80.840  -53.618 34.043  1.00 54.17  ? 71  LEU F CA   1 
ATOM   9114  C  C    . LEU F 2 71  ? 79.337  -53.361 33.972  1.00 53.53  ? 71  LEU F C    1 
ATOM   9115  O  O    . LEU F 2 71  ? 78.614  -53.835 34.850  1.00 51.93  ? 71  LEU F O    1 
ATOM   9116  C  CB   . LEU F 2 71  ? 81.495  -53.617 32.662  1.00 46.57  ? 71  LEU F CB   1 
ATOM   9117  C  CG   . LEU F 2 71  ? 83.014  -53.497 32.617  1.00 57.03  ? 71  LEU F CG   1 
ATOM   9118  C  CD1  . LEU F 2 71  ? 83.457  -52.929 31.282  1.00 57.13  ? 71  LEU F CD1  1 
ATOM   9119  C  CD2  . LEU F 2 71  ? 83.544  -52.646 33.754  1.00 55.19  ? 71  LEU F CD2  1 
ATOM   9120  N  N    . ARG F 2 72  ? 78.887  -52.676 32.928  1.00 57.08  ? 72  ARG F N    1 
ATOM   9121  C  CA   . ARG F 2 72  ? 77.470  -52.267 32.878  1.00 52.19  ? 72  ARG F CA   1 
ATOM   9122  C  C    . ARG F 2 72  ? 76.893  -52.328 31.470  1.00 57.48  ? 72  ARG F C    1 
ATOM   9123  O  O    . ARG F 2 72  ? 77.425  -51.640 30.590  1.00 63.86  ? 72  ARG F O    1 
ATOM   9124  C  CB   . ARG F 2 72  ? 77.394  -50.821 33.369  1.00 50.38  ? 72  ARG F CB   1 
ATOM   9125  C  CG   . ARG F 2 72  ? 76.549  -50.585 34.606  1.00 54.69  ? 72  ARG F CG   1 
ATOM   9126  C  CD   . ARG F 2 72  ? 76.596  -49.106 34.920  1.00 54.92  ? 72  ARG F CD   1 
ATOM   9127  N  NE   . ARG F 2 72  ? 76.668  -48.827 36.344  1.00 55.84  ? 72  ARG F NE   1 
ATOM   9128  C  CZ   . ARG F 2 72  ? 77.701  -48.272 36.961  1.00 51.75  ? 72  ARG F CZ   1 
ATOM   9129  N  NH1  . ARG F 2 72  ? 78.777  -47.921 36.280  1.00 49.16  ? 72  ARG F NH1  1 
ATOM   9130  N  NH2  . ARG F 2 72  ? 77.652  -48.076 38.264  1.00 47.20  ? 72  ARG F NH2  1 
ATOM   9131  N  N    . LEU F 2 73  ? 75.854  -53.130 31.296  1.00 52.81  ? 73  LEU F N    1 
ATOM   9132  C  CA   . LEU F 2 73  ? 75.128  -53.139 30.014  1.00 61.48  ? 73  LEU F CA   1 
ATOM   9133  C  C    . LEU F 2 73  ? 73.843  -52.358 30.267  1.00 53.98  ? 73  LEU F C    1 
ATOM   9134  O  O    . LEU F 2 73  ? 72.876  -52.956 30.717  1.00 56.34  ? 73  LEU F O    1 
ATOM   9135  C  CB   . LEU F 2 73  ? 74.862  -54.584 29.592  1.00 60.99  ? 73  LEU F CB   1 
ATOM   9136  C  CG   . LEU F 2 73  ? 75.899  -55.182 28.649  1.00 63.18  ? 73  LEU F CG   1 
ATOM   9137  C  CD1  . LEU F 2 73  ? 75.412  -56.508 28.097  1.00 64.25  ? 73  LEU F CD1  1 
ATOM   9138  C  CD2  . LEU F 2 73  ? 76.208  -54.214 27.523  1.00 64.51  ? 73  LEU F CD2  1 
ATOM   9139  N  N    . ARG F 2 74  ? 73.876  -51.053 30.032  1.00 54.58  ? 74  ARG F N    1 
ATOM   9140  C  CA   . ARG F 2 74  ? 72.715  -50.185 30.230  1.00 60.66  ? 74  ARG F CA   1 
ATOM   9141  C  C    . ARG F 2 74  ? 71.659  -50.423 29.151  1.00 57.80  ? 74  ARG F C    1 
ATOM   9142  O  O    . ARG F 2 74  ? 71.965  -50.871 28.040  1.00 60.95  ? 74  ARG F O    1 
ATOM   9143  C  CB   . ARG F 2 74  ? 73.148  -48.710 30.229  1.00 55.74  ? 74  ARG F CB   1 
ATOM   9144  C  CG   . ARG F 2 74  ? 74.243  -48.420 31.248  1.00 62.04  ? 74  ARG F CG   1 
ATOM   9145  C  CD   . ARG F 2 74  ? 74.533  -46.935 31.456  1.00 57.73  ? 74  ARG F CD   1 
ATOM   9146  N  NE   . ARG F 2 74  ? 74.109  -46.548 32.789  1.00 58.07  ? 74  ARG F NE   1 
ATOM   9147  C  CZ   . ARG F 2 74  ? 74.911  -46.109 33.745  1.00 46.11  ? 74  ARG F CZ   1 
ATOM   9148  N  NH1  . ARG F 2 74  ? 76.201  -45.985 33.522  1.00 56.40  ? 74  ARG F NH1  1 
ATOM   9149  N  NH2  . ARG F 2 74  ? 74.406  -45.804 34.928  1.00 56.69  ? 74  ARG F NH2  1 
ATOM   9150  N  N    . GLY F 2 75  ? 70.407  -50.107 29.483  1.00 56.85  ? 75  GLY F N    1 
ATOM   9151  C  CA   . GLY F 2 75  ? 69.290  -50.331 28.575  1.00 55.76  ? 75  GLY F CA   1 
ATOM   9152  C  C    . GLY F 2 75  ? 68.052  -49.496 28.850  1.00 59.50  ? 75  GLY F C    1 
ATOM   9153  O  O    . GLY F 2 75  ? 67.594  -49.420 29.996  1.00 61.22  ? 75  GLY F O    1 
ATOM   9154  N  N    . VAL G 1 7   ? 20.815  -41.947 2.642   1.00 83.64  ? 214 VAL G N    1 
ATOM   9155  C  CA   . VAL G 1 7   ? 20.758  -40.471 2.428   1.00 87.07  ? 214 VAL G CA   1 
ATOM   9156  C  C    . VAL G 1 7   ? 20.968  -39.736 3.757   1.00 87.31  ? 214 VAL G C    1 
ATOM   9157  O  O    . VAL G 1 7   ? 20.350  -40.136 4.756   1.00 86.20  ? 214 VAL G O    1 
ATOM   9158  C  CB   . VAL G 1 7   ? 19.437  -40.052 1.759   1.00 85.33  ? 214 VAL G CB   1 
ATOM   9159  C  CG1  . VAL G 1 7   ? 19.568  -38.720 1.045   1.00 90.27  ? 214 VAL G CG1  1 
ATOM   9160  C  CG2  . VAL G 1 7   ? 18.919  -41.113 0.804   1.00 92.76  ? 214 VAL G CG2  1 
ATOM   9161  N  N    . GLY G 1 8   ? 21.802  -38.694 3.762   1.00 89.84  ? 215 GLY G N    1 
ATOM   9162  C  CA   . GLY G 1 8   ? 22.035  -37.889 4.943   1.00 86.86  ? 215 GLY G CA   1 
ATOM   9163  C  C    . GLY G 1 8   ? 21.017  -36.768 5.099   1.00 85.42  ? 215 GLY G C    1 
ATOM   9164  O  O    . GLY G 1 8   ? 20.122  -36.569 4.274   1.00 85.50  ? 215 GLY G O    1 
ATOM   9165  N  N    . LEU G 1 9   ? 21.162  -36.008 6.191   1.00 85.70  ? 216 LEU G N    1 
ATOM   9166  C  CA   . LEU G 1 9   ? 20.238  -34.875 6.477   1.00 85.24  ? 216 LEU G CA   1 
ATOM   9167  C  C    . LEU G 1 9   ? 21.055  -33.596 6.677   1.00 84.34  ? 216 LEU G C    1 
ATOM   9168  O  O    . LEU G 1 9   ? 21.898  -33.587 7.578   1.00 82.18  ? 216 LEU G O    1 
ATOM   9169  N  N    . LYS G 1 10  ? 20.777  -32.548 5.899   1.00 84.53  ? 217 LYS G N    1 
ATOM   9170  C  CA   . LYS G 1 10  ? 21.569  -31.285 5.943   1.00 84.63  ? 217 LYS G CA   1 
ATOM   9171  C  C    . LYS G 1 10  ? 21.549  -30.642 7.334   1.00 84.02  ? 217 LYS G C    1 
ATOM   9172  O  O    . LYS G 1 10  ? 20.452  -30.447 7.876   1.00 88.14  ? 217 LYS G O    1 
ATOM   9173  C  CB   . LYS G 1 10  ? 21.020  -30.299 4.911   1.00 78.26  ? 217 LYS G CB   1 
ATOM   9174  C  CG   . LYS G 1 10  ? 21.488  -30.502 3.479   1.00 80.39  ? 217 LYS G CG   1 
ATOM   9175  C  CD   . LYS G 1 10  ? 20.898  -29.483 2.532   1.00 88.43  ? 217 LYS G CD   1 
ATOM   9176  C  CE   . LYS G 1 10  ? 19.836  -30.060 1.622   1.00 96.01  ? 217 LYS G CE   1 
ATOM   9177  N  NZ   . LYS G 1 10  ? 20.427  -30.694 0.420   1.00 89.18  ? 217 LYS G NZ   1 
ATOM   9178  N  N    . ASN G 1 11  ? 22.724  -30.304 7.872   1.00 80.87  ? 218 ASN G N    1 
ATOM   9179  C  CA   . ASN G 1 11  ? 22.811  -29.618 9.189   1.00 80.44  ? 218 ASN G CA   1 
ATOM   9180  C  C    . ASN G 1 11  ? 22.549  -28.133 8.978   1.00 79.23  ? 218 ASN G C    1 
ATOM   9181  O  O    . ASN G 1 11  ? 23.363  -27.480 8.309   1.00 79.78  ? 218 ASN G O    1 
ATOM   9182  C  CB   . ASN G 1 11  ? 24.158  -29.829 9.877   1.00 78.81  ? 218 ASN G CB   1 
ATOM   9183  C  CG   . ASN G 1 11  ? 24.307  -29.060 11.172  1.00 81.45  ? 218 ASN G CG   1 
ATOM   9184  O  OD1  . ASN G 1 11  ? 23.350  -28.896 11.922  1.00 75.74  ? 218 ASN G OD1  1 
ATOM   9185  N  ND2  . ASN G 1 11  ? 25.511  -28.586 11.444  1.00 82.57  ? 218 ASN G ND2  1 
ATOM   9186  N  N    . GLN G 1 12  ? 21.457  -27.634 9.550   1.00 79.94  ? 219 GLN G N    1 
ATOM   9187  C  CA   . GLN G 1 12  ? 21.079  -26.210 9.374   1.00 83.34  ? 219 GLN G CA   1 
ATOM   9188  C  C    . GLN G 1 12  ? 22.039  -25.314 10.171  1.00 80.99  ? 219 GLN G C    1 
ATOM   9189  O  O    . GLN G 1 12  ? 21.989  -24.090 9.984   1.00 75.51  ? 219 GLN G O    1 
ATOM   9190  C  CB   . GLN G 1 12  ? 19.614  -26.040 9.777   1.00 78.75  ? 219 GLN G CB   1 
ATOM   9191  N  N    . GLY G 1 13  ? 22.894  -25.914 10.999  1.00 81.78  ? 220 GLY G N    1 
ATOM   9192  C  CA   . GLY G 1 13  ? 23.845  -25.148 11.821  1.00 74.60  ? 220 GLY G CA   1 
ATOM   9193  C  C    . GLY G 1 13  ? 24.163  -25.883 13.105  1.00 74.49  ? 220 GLY G C    1 
ATOM   9194  O  O    . GLY G 1 13  ? 25.349  -26.098 13.383  1.00 76.59  ? 220 GLY G O    1 
ATOM   9195  N  N    . ALA G 1 14  ? 23.127  -26.268 13.849  1.00 78.46  ? 221 ALA G N    1 
ATOM   9196  C  CA   . ALA G 1 14  ? 23.343  -26.984 15.124  1.00 78.45  ? 221 ALA G CA   1 
ATOM   9197  C  C    . ALA G 1 14  ? 22.298  -28.090 15.311  1.00 74.17  ? 221 ALA G C    1 
ATOM   9198  O  O    . ALA G 1 14  ? 22.142  -28.549 16.450  1.00 71.01  ? 221 ALA G O    1 
ATOM   9199  C  CB   . ALA G 1 14  ? 23.279  -25.990 16.249  1.00 70.22  ? 221 ALA G CB   1 
ATOM   9200  N  N    . THR G 1 15  ? 21.639  -28.514 14.238  1.00 62.28  ? 222 THR G N    1 
ATOM   9201  C  CA   . THR G 1 15  ? 20.552  -29.520 14.335  1.00 70.28  ? 222 THR G CA   1 
ATOM   9202  C  C    . THR G 1 15  ? 21.109  -30.945 14.292  1.00 66.79  ? 222 THR G C    1 
ATOM   9203  O  O    . THR G 1 15  ? 20.386  -31.821 13.820  1.00 64.90  ? 222 THR G O    1 
ATOM   9204  C  CB   . THR G 1 15  ? 19.529  -29.284 13.222  1.00 71.06  ? 222 THR G CB   1 
ATOM   9205  O  OG1  . THR G 1 15  ? 20.169  -29.447 11.957  1.00 72.44  ? 222 THR G OG1  1 
ATOM   9206  C  CG2  . THR G 1 15  ? 18.906  -27.909 13.299  1.00 69.20  ? 222 THR G CG2  1 
ATOM   9207  N  N    . CYS G 1 16  ? 22.325  -31.177 14.783  1.00 64.16  ? 223 CYS G N    1 
ATOM   9208  C  CA   . CYS G 1 16  ? 22.791  -32.558 14.757  1.00 68.70  ? 223 CYS G CA   1 
ATOM   9209  C  C    . CYS G 1 16  ? 21.923  -33.448 15.642  1.00 72.59  ? 223 CYS G C    1 
ATOM   9210  O  O    . CYS G 1 16  ? 21.728  -34.629 15.330  1.00 68.19  ? 223 CYS G O    1 
ATOM   9211  C  CB   . CYS G 1 16  ? 24.250  -32.644 15.194  1.00 68.92  ? 223 CYS G CB   1 
ATOM   9212  S  SG   . CYS G 1 16  ? 24.655  -31.730 16.682  1.00 75.99  ? 223 CYS G SG   1 
ATOM   9213  N  N    . TYR G 1 17  ? 21.401  -32.893 16.747  1.00 68.26  ? 224 TYR G N    1 
ATOM   9214  C  CA   . TYR G 1 17  ? 20.466  -33.625 17.598  1.00 69.25  ? 224 TYR G CA   1 
ATOM   9215  C  C    . TYR G 1 17  ? 19.210  -34.018 16.825  1.00 71.76  ? 224 TYR G C    1 
ATOM   9216  O  O    . TYR G 1 17  ? 18.717  -35.144 16.955  1.00 67.97  ? 224 TYR G O    1 
ATOM   9217  C  CB   . TYR G 1 17  ? 20.093  -32.777 18.826  1.00 70.75  ? 224 TYR G CB   1 
ATOM   9218  C  CG   . TYR G 1 17  ? 19.262  -31.545 18.493  1.00 70.99  ? 224 TYR G CG   1 
ATOM   9219  C  CD1  . TYR G 1 17  ? 17.871  -31.603 18.464  1.00 66.85  ? 224 TYR G CD1  1 
ATOM   9220  C  CD2  . TYR G 1 17  ? 19.875  -30.322 18.201  1.00 70.43  ? 224 TYR G CD2  1 
ATOM   9221  C  CE1  . TYR G 1 17  ? 17.116  -30.489 18.145  1.00 70.22  ? 224 TYR G CE1  1 
ATOM   9222  C  CE2  . TYR G 1 17  ? 19.128  -29.201 17.885  1.00 67.52  ? 224 TYR G CE2  1 
ATOM   9223  C  CZ   . TYR G 1 17  ? 17.745  -29.291 17.859  1.00 70.57  ? 224 TYR G CZ   1 
ATOM   9224  O  OH   . TYR G 1 17  ? 16.977  -28.189 17.542  1.00 74.42  ? 224 TYR G OH   1 
ATOM   9225  N  N    . MET G 1 18  ? 18.675  -33.099 16.017  1.00 72.52  ? 225 MET G N    1 
ATOM   9226  C  CA   . MET G 1 18  ? 17.438  -33.377 15.298  1.00 70.37  ? 225 MET G CA   1 
ATOM   9227  C  C    . MET G 1 18  ? 17.666  -34.333 14.138  1.00 70.58  ? 225 MET G C    1 
ATOM   9228  O  O    . MET G 1 18  ? 16.792  -35.146 13.819  1.00 71.26  ? 225 MET G O    1 
ATOM   9229  C  CB   . MET G 1 18  ? 16.818  -32.072 14.797  1.00 66.61  ? 225 MET G CB   1 
ATOM   9230  C  CG   . MET G 1 18  ? 15.615  -32.285 13.914  1.00 64.18  ? 225 MET G CG   1 
ATOM   9231  S  SD   . MET G 1 18  ? 14.740  -30.760 13.577  1.00 75.41  ? 225 MET G SD   1 
ATOM   9232  C  CE   . MET G 1 18  ? 15.883  -29.994 12.443  1.00 76.27  ? 225 MET G CE   1 
ATOM   9233  N  N    . ASN G 1 19  ? 18.824  -34.247 13.488  1.00 68.48  ? 226 ASN G N    1 
ATOM   9234  C  CA   . ASN G 1 19  ? 19.063  -35.108 12.337  1.00 71.44  ? 226 ASN G CA   1 
ATOM   9235  C  C    . ASN G 1 19  ? 19.273  -36.550 12.774  1.00 70.24  ? 226 ASN G C    1 
ATOM   9236  O  O    . ASN G 1 19  ? 18.786  -37.481 12.118  1.00 63.97  ? 226 ASN G O    1 
ATOM   9237  C  CB   . ASN G 1 19  ? 20.236  -34.567 11.505  1.00 65.69  ? 226 ASN G CB   1 
ATOM   9238  C  CG   . ASN G 1 19  ? 19.860  -33.286 10.758  1.00 76.10  ? 226 ASN G CG   1 
ATOM   9239  O  OD1  . ASN G 1 19  ? 18.677  -32.982 10.590  1.00 77.97  ? 226 ASN G OD1  1 
ATOM   9240  N  ND2  . ASN G 1 19  ? 20.860  -32.544 10.288  1.00 76.17  ? 226 ASN G ND2  1 
ATOM   9241  N  N    . SER G 1 20  ? 19.947  -36.753 13.908  1.00 67.81  ? 227 SER G N    1 
ATOM   9242  C  CA   . SER G 1 20  ? 20.168  -38.111 14.395  1.00 69.73  ? 227 SER G CA   1 
ATOM   9243  C  C    . SER G 1 20  ? 18.853  -38.784 14.762  1.00 73.91  ? 227 SER G C    1 
ATOM   9244  O  O    . SER G 1 20  ? 18.621  -39.948 14.411  1.00 73.28  ? 227 SER G O    1 
ATOM   9245  C  CB   . SER G 1 20  ? 21.121  -38.108 15.597  1.00 67.66  ? 227 SER G CB   1 
ATOM   9246  O  OG   . SER G 1 20  ? 22.211  -37.217 15.434  1.00 57.97  ? 227 SER G OG   1 
ATOM   9247  N  N    . LEU G 1 21  ? 17.973  -38.061 15.453  1.00 71.77  ? 228 LEU G N    1 
ATOM   9248  C  CA   . LEU G 1 21  ? 16.731  -38.668 15.910  1.00 71.08  ? 228 LEU G CA   1 
ATOM   9249  C  C    . LEU G 1 21  ? 15.790  -38.946 14.745  1.00 68.61  ? 228 LEU G C    1 
ATOM   9250  O  O    . LEU G 1 21  ? 15.048  -39.929 14.776  1.00 72.96  ? 228 LEU G O    1 
ATOM   9251  C  CB   . LEU G 1 21  ? 16.080  -37.766 16.974  1.00 73.11  ? 228 LEU G CB   1 
ATOM   9252  C  CG   . LEU G 1 21  ? 14.864  -38.205 17.804  1.00 68.06  ? 228 LEU G CG   1 
ATOM   9253  C  CD1  . LEU G 1 21  ? 13.592  -38.119 17.011  1.00 74.62  ? 228 LEU G CD1  1 
ATOM   9254  C  CD2  . LEU G 1 21  ? 15.057  -39.617 18.333  1.00 67.49  ? 228 LEU G CD2  1 
ATOM   9255  N  N    . LEU G 1 22  ? 15.819  -38.112 13.716  1.00 67.17  ? 229 LEU G N    1 
ATOM   9256  C  CA   . LEU G 1 22  ? 14.970  -38.345 12.523  1.00 67.80  ? 229 LEU G CA   1 
ATOM   9257  C  C    . LEU G 1 22  ? 15.451  -39.612 11.815  1.00 72.47  ? 229 LEU G C    1 
ATOM   9258  O  O    . LEU G 1 22  ? 14.592  -40.360 11.348  1.00 70.15  ? 229 LEU G O    1 
ATOM   9259  C  CB   . LEU G 1 22  ? 15.032  -37.106 11.632  1.00 66.42  ? 229 LEU G CB   1 
ATOM   9260  C  CG   . LEU G 1 22  ? 14.016  -36.021 11.969  1.00 69.96  ? 229 LEU G CG   1 
ATOM   9261  C  CD1  . LEU G 1 22  ? 14.293  -34.763 11.170  1.00 67.62  ? 229 LEU G CD1  1 
ATOM   9262  C  CD2  . LEU G 1 22  ? 12.606  -36.516 11.712  1.00 59.61  ? 229 LEU G CD2  1 
ATOM   9263  N  N    . GLN G 1 23  ? 16.764  -39.821 11.700  1.00 71.48  ? 230 GLN G N    1 
ATOM   9264  C  CA   . GLN G 1 23  ? 17.277  -41.088 11.189  1.00 65.47  ? 230 GLN G CA   1 
ATOM   9265  C  C    . GLN G 1 23  ? 16.791  -42.262 12.038  1.00 76.65  ? 230 GLN G C    1 
ATOM   9266  O  O    . GLN G 1 23  ? 16.427  -43.318 11.501  1.00 75.06  ? 230 GLN G O    1 
ATOM   9267  N  N    . THR G 1 24  ? 16.764  -42.093 13.368  1.00 74.92  ? 231 THR G N    1 
ATOM   9268  C  CA   . THR G 1 24  ? 16.269  -43.147 14.251  1.00 69.93  ? 231 THR G CA   1 
ATOM   9269  C  C    . THR G 1 24  ? 14.773  -43.398 14.048  1.00 73.71  ? 231 THR G C    1 
ATOM   9270  O  O    . THR G 1 24  ? 14.320  -44.546 14.116  1.00 76.05  ? 231 THR G O    1 
ATOM   9271  C  CB   . THR G 1 24  ? 16.560  -42.795 15.714  1.00 71.51  ? 231 THR G CB   1 
ATOM   9272  O  OG1  . THR G 1 24  ? 17.942  -42.463 15.861  1.00 74.11  ? 231 THR G OG1  1 
ATOM   9273  C  CG2  . THR G 1 24  ? 16.265  -43.968 16.629  1.00 72.08  ? 231 THR G CG2  1 
ATOM   9274  N  N    . LEU G 1 25  ? 13.986  -42.350 13.802  1.00 72.14  ? 232 LEU G N    1 
ATOM   9275  C  CA   . LEU G 1 25  ? 12.556  -42.575 13.624  1.00 71.44  ? 232 LEU G CA   1 
ATOM   9276  C  C    . LEU G 1 25  ? 12.224  -43.022 12.205  1.00 77.65  ? 232 LEU G C    1 
ATOM   9277  O  O    . LEU G 1 25  ? 11.384  -43.911 12.024  1.00 78.83  ? 232 LEU G O    1 
ATOM   9278  C  CB   . LEU G 1 25  ? 11.760  -41.320 13.966  1.00 67.58  ? 232 LEU G CB   1 
ATOM   9279  C  CG   . LEU G 1 25  ? 11.846  -40.752 15.384  1.00 74.86  ? 232 LEU G CG   1 
ATOM   9280  C  CD1  . LEU G 1 25  ? 10.790  -39.655 15.514  1.00 79.38  ? 232 LEU G CD1  1 
ATOM   9281  C  CD2  . LEU G 1 25  ? 11.665  -41.816 16.459  1.00 64.24  ? 232 LEU G CD2  1 
ATOM   9282  N  N    . PHE G 1 26  ? 12.894  -42.475 11.196  1.00 73.27  ? 233 PHE G N    1 
ATOM   9283  C  CA   . PHE G 1 26  ? 12.660  -42.952 9.809   1.00 72.85  ? 233 PHE G CA   1 
ATOM   9284  C  C    . PHE G 1 26  ? 12.887  -44.462 9.729   1.00 74.39  ? 233 PHE G C    1 
ATOM   9285  O  O    . PHE G 1 26  ? 12.047  -45.145 9.121   1.00 64.91  ? 233 PHE G O    1 
ATOM   9286  N  N    . PHE G 1 27  ? 13.944  -44.954 10.384  1.00 71.46  ? 234 PHE G N    1 
ATOM   9287  C  CA   . PHE G 1 27  ? 14.295  -46.399 10.383  1.00 67.54  ? 234 PHE G CA   1 
ATOM   9288  C  C    . PHE G 1 27  ? 13.282  -47.218 11.179  1.00 72.72  ? 234 PHE G C    1 
ATOM   9289  O  O    . PHE G 1 27  ? 13.419  -48.446 11.201  1.00 69.81  ? 234 PHE G O    1 
ATOM   9290  N  N    . THR G 1 28  ? 12.358  -46.565 11.875  1.00 72.38  ? 235 THR G N    1 
ATOM   9291  C  CA   . THR G 1 28  ? 11.257  -47.303 12.538  1.00 76.45  ? 235 THR G CA   1 
ATOM   9292  C  C    . THR G 1 28  ? 10.194  -47.359 11.446  1.00 82.30  ? 235 THR G C    1 
ATOM   9293  O  O    . THR G 1 28  ? 9.475   -46.363 11.291  1.00 83.42  ? 235 THR G O    1 
ATOM   9294  C  CB   . THR G 1 28  ? 10.886  -46.639 13.869  1.00 74.31  ? 235 THR G CB   1 
ATOM   9295  O  OG1  . THR G 1 28  ? 12.081  -46.324 14.583  1.00 72.02  ? 235 THR G OG1  1 
ATOM   9296  C  CG2  . THR G 1 28  ? 10.003  -47.514 14.730  1.00 72.71  ? 235 THR G CG2  1 
ATOM   9297  N  N    . ASN G 1 29  ? 10.104  -48.469 10.712  1.00 79.25  ? 236 ASN G N    1 
ATOM   9298  C  CA   . ASN G 1 29  ? 9.257   -48.490 9.523   1.00 79.46  ? 236 ASN G CA   1 
ATOM   9299  C  C    . ASN G 1 29  ? 7.774   -48.508 9.885   1.00 80.32  ? 236 ASN G C    1 
ATOM   9300  O  O    . ASN G 1 29  ? 6.960   -47.865 9.208   1.00 79.14  ? 236 ASN G O    1 
ATOM   9301  C  CB   . ASN G 1 29  ? 9.634   -49.680 8.639   1.00 81.08  ? 236 ASN G CB   1 
ATOM   9302  C  CG   . ASN G 1 29  ? 11.006  -49.513 7.982   1.00 82.26  ? 236 ASN G CG   1 
ATOM   9303  O  OD1  . ASN G 1 29  ? 11.975  -49.070 8.615   1.00 76.89  ? 236 ASN G OD1  1 
ATOM   9304  N  ND2  . ASN G 1 29  ? 11.092  -49.877 6.708   1.00 83.22  ? 236 ASN G ND2  1 
ATOM   9305  N  N    . GLN G 1 30  ? 7.399   -49.228 10.946  1.00 80.90  ? 237 GLN G N    1 
ATOM   9306  C  CA   . GLN G 1 30  ? 6.014   -49.181 11.407  1.00 81.90  ? 237 GLN G CA   1 
ATOM   9307  C  C    . GLN G 1 30  ? 5.593   -47.740 11.671  1.00 82.65  ? 237 GLN G C    1 
ATOM   9308  O  O    . GLN G 1 30  ? 4.560   -47.271 11.171  1.00 74.19  ? 237 GLN G O    1 
ATOM   9309  N  N    . LEU G 1 31  ? 6.417   -47.012 12.432  1.00 80.94  ? 238 LEU G N    1 
ATOM   9310  C  CA   . LEU G 1 31  ? 6.142   -45.609 12.706  1.00 77.74  ? 238 LEU G CA   1 
ATOM   9311  C  C    . LEU G 1 31  ? 6.104   -44.797 11.414  1.00 83.44  ? 238 LEU G C    1 
ATOM   9312  O  O    . LEU G 1 31  ? 5.191   -43.981 11.211  1.00 78.26  ? 238 LEU G O    1 
ATOM   9313  C  CB   . LEU G 1 31  ? 7.193   -45.065 13.677  1.00 78.56  ? 238 LEU G CB   1 
ATOM   9314  C  CG   . LEU G 1 31  ? 7.020   -43.674 14.296  1.00 76.99  ? 238 LEU G CG   1 
ATOM   9315  C  CD1  . LEU G 1 31  ? 7.665   -42.600 13.418  1.00 77.74  ? 238 LEU G CD1  1 
ATOM   9316  C  CD2  . LEU G 1 31  ? 5.537   -43.373 14.542  1.00 77.82  ? 238 LEU G CD2  1 
ATOM   9317  N  N    . ARG G 1 32  ? 7.073   -45.033 10.516  1.00 80.82  ? 239 ARG G N    1 
ATOM   9318  C  CA   . ARG G 1 32  ? 7.141   -44.286 9.262   1.00 77.23  ? 239 ARG G CA   1 
ATOM   9319  C  C    . ARG G 1 32  ? 5.862   -44.456 8.448   1.00 82.21  ? 239 ARG G C    1 
ATOM   9320  O  O    . ARG G 1 32  ? 5.304   -43.477 7.932   1.00 79.55  ? 239 ARG G O    1 
ATOM   9321  N  N    . LYS G 1 33  ? 5.378   -45.699 8.330   1.00 83.53  ? 240 LYS G N    1 
ATOM   9322  C  CA   . LYS G 1 33  ? 4.155   -45.960 7.577   1.00 76.74  ? 240 LYS G CA   1 
ATOM   9323  C  C    . LYS G 1 33  ? 2.966   -45.262 8.218   1.00 76.98  ? 240 LYS G C    1 
ATOM   9324  O  O    . LYS G 1 33  ? 2.170   -44.604 7.536   1.00 76.27  ? 240 LYS G O    1 
ATOM   9325  N  N    . ALA G 1 34  ? 2.866   -45.365 9.531   1.00 77.35  ? 241 ALA G N    1 
ATOM   9326  C  CA   . ALA G 1 34  ? 1.779   -44.649 10.218  1.00 78.05  ? 241 ALA G CA   1 
ATOM   9327  C  C    . ALA G 1 34  ? 1.885   -43.164 9.896   1.00 83.64  ? 241 ALA G C    1 
ATOM   9328  O  O    . ALA G 1 34  ? 0.838   -42.532 9.713   1.00 86.93  ? 241 ALA G O    1 
ATOM   9329  C  CB   . ALA G 1 34  ? 1.895   -44.891 11.688  1.00 76.34  ? 241 ALA G CB   1 
ATOM   9330  N  N    . VAL G 1 35  ? 3.107   -42.640 9.826   1.00 74.75  ? 242 VAL G N    1 
ATOM   9331  C  CA   . VAL G 1 35  ? 3.270   -41.206 9.607   1.00 80.75  ? 242 VAL G CA   1 
ATOM   9332  C  C    . VAL G 1 35  ? 2.795   -40.816 8.206   1.00 85.17  ? 242 VAL G C    1 
ATOM   9333  O  O    . VAL G 1 35  ? 2.148   -39.775 8.032   1.00 84.93  ? 242 VAL G O    1 
ATOM   9334  C  CB   . VAL G 1 35  ? 4.729   -40.774 9.871   1.00 80.08  ? 242 VAL G CB   1 
ATOM   9335  C  CG1  . VAL G 1 35  ? 4.996   -39.356 9.345   1.00 78.41  ? 242 VAL G CG1  1 
ATOM   9336  C  CG2  . VAL G 1 35  ? 5.043   -40.842 11.369  1.00 76.93  ? 242 VAL G CG2  1 
ATOM   9337  N  N    . TYR G 1 36  ? 3.071   -41.652 7.204   1.00 85.50  ? 243 TYR G N    1 
ATOM   9338  C  CA   . TYR G 1 36  ? 2.586   -41.364 5.826   1.00 81.13  ? 243 TYR G CA   1 
ATOM   9339  C  C    . TYR G 1 36  ? 1.055   -41.386 5.780   1.00 81.54  ? 243 TYR G C    1 
ATOM   9340  O  O    . TYR G 1 36  ? 0.469   -40.564 5.064   1.00 77.14  ? 243 TYR G O    1 
ATOM   9341  C  CB   . TYR G 1 36  ? 3.122   -42.383 4.824   1.00 82.40  ? 243 TYR G CB   1 
ATOM   9342  C  CG   . TYR G 1 36  ? 4.592   -42.299 4.505   1.00 80.28  ? 243 TYR G CG   1 
ATOM   9343  C  CD1  . TYR G 1 36  ? 5.183   -41.105 4.133   1.00 77.28  ? 243 TYR G CD1  1 
ATOM   9344  C  CD2  . TYR G 1 36  ? 5.385   -43.432 4.542   1.00 75.81  ? 243 TYR G CD2  1 
ATOM   9345  C  CE1  . TYR G 1 36  ? 6.532   -41.035 3.823   1.00 81.70  ? 243 TYR G CE1  1 
ATOM   9346  C  CE2  . TYR G 1 36  ? 6.733   -43.381 4.236   1.00 78.17  ? 243 TYR G CE2  1 
ATOM   9347  C  CZ   . TYR G 1 36  ? 7.309   -42.178 3.876   1.00 80.55  ? 243 TYR G CZ   1 
ATOM   9348  O  OH   . TYR G 1 36  ? 8.636   -42.132 3.572   1.00 77.56  ? 243 TYR G OH   1 
ATOM   9349  N  N    . MET G 1 37  ? 0.434   -42.306 6.517   1.00 81.95  ? 244 MET G N    1 
ATOM   9350  C  CA   . MET G 1 37  ? -1.016  -42.431 6.480   1.00 82.16  ? 244 MET G CA   1 
ATOM   9351  C  C    . MET G 1 37  ? -1.735  -41.303 7.204   1.00 88.20  ? 244 MET G C    1 
ATOM   9352  O  O    . MET G 1 37  ? -2.957  -41.183 7.054   1.00 90.46  ? 244 MET G O    1 
ATOM   9353  N  N    . MET G 1 38  ? -1.001  -40.534 8.007   1.00 90.76  ? 245 MET G N    1 
ATOM   9354  C  CA   . MET G 1 38  ? -1.619  -39.453 8.811   1.00 87.29  ? 245 MET G CA   1 
ATOM   9355  C  C    . MET G 1 38  ? -2.465  -38.558 7.906   1.00 91.68  ? 245 MET G C    1 
ATOM   9356  O  O    . MET G 1 38  ? -1.937  -38.077 6.892   1.00 91.12  ? 245 MET G O    1 
ATOM   9357  C  CB   . MET G 1 38  ? -0.536  -38.619 9.491   1.00 80.11  ? 245 MET G CB   1 
ATOM   9358  C  CG   . MET G 1 38  ? 0.108   -39.337 10.642  1.00 85.69  ? 245 MET G CG   1 
ATOM   9359  S  SD   . MET G 1 38  ? 0.876   -38.189 11.785  1.00 81.29  ? 245 MET G SD   1 
ATOM   9360  C  CE   . MET G 1 38  ? -0.570  -37.272 12.311  1.00 76.95  ? 245 MET G CE   1 
ATOM   9361  N  N    . PRO G 1 39  ? -3.782  -38.318 8.181   1.00 91.81  ? 246 PRO G N    1 
ATOM   9362  C  CA   . PRO G 1 39  ? -4.577  -37.396 7.363   1.00 91.98  ? 246 PRO G CA   1 
ATOM   9363  C  C    . PRO G 1 39  ? -4.041  -35.959 7.350   1.00 94.32  ? 246 PRO G C    1 
ATOM   9364  O  O    . PRO G 1 39  ? -4.390  -35.186 8.218   1.00 95.79  ? 246 PRO G O    1 
ATOM   9365  C  CB   . PRO G 1 39  ? -5.982  -37.406 7.982   1.00 91.13  ? 246 PRO G CB   1 
ATOM   9366  C  CG   . PRO G 1 39  ? -5.778  -37.914 9.374   1.00 88.94  ? 246 PRO G CG   1 
ATOM   9367  C  CD   . PRO G 1 39  ? -4.671  -38.925 9.209   1.00 86.50  ? 246 PRO G CD   1 
ATOM   9368  N  N    . THR G 1 40  ? -3.240  -35.628 6.339   1.00 94.07  ? 247 THR G N    1 
ATOM   9369  C  CA   . THR G 1 40  ? -2.671  -34.264 6.219   1.00 94.44  ? 247 THR G CA   1 
ATOM   9370  C  C    . THR G 1 40  ? -3.605  -33.406 5.359   1.00 101.43 ? 247 THR G C    1 
ATOM   9371  O  O    . THR G 1 40  ? -4.797  -33.327 5.710   1.00 101.13 ? 247 THR G O    1 
ATOM   9372  C  CB   . THR G 1 40  ? -1.234  -34.340 5.687   1.00 93.49  ? 247 THR G CB   1 
ATOM   9373  O  OG1  . THR G 1 40  ? -1.231  -35.053 4.450   1.00 98.14  ? 247 THR G OG1  1 
ATOM   9374  C  CG2  . THR G 1 40  ? -0.284  -35.010 6.656   1.00 90.32  ? 247 THR G CG2  1 
ATOM   9375  N  N    . GLU G 1 41  ? -3.083  -32.790 4.294   1.00 105.16 ? 248 GLU G N    1 
ATOM   9376  C  CA   . GLU G 1 41  ? -3.881  -31.909 3.394   1.00 103.65 ? 248 GLU G CA   1 
ATOM   9377  C  C    . GLU G 1 41  ? -4.846  -31.053 4.220   1.00 107.54 ? 248 GLU G C    1 
ATOM   9378  O  O    . GLU G 1 41  ? -5.675  -30.368 3.594   1.00 115.20 ? 248 GLU G O    1 
ATOM   9379  C  CB   . GLU G 1 41  ? -4.617  -32.744 2.347   1.00 100.46 ? 248 GLU G CB   1 
ATOM   9380  N  N    . SER G 1 46  ? 2.393   -25.705 5.378   1.00 98.33  ? 253 SER G N    1 
ATOM   9381  C  CA   . SER G 1 46  ? 3.762   -26.041 5.769   1.00 91.11  ? 253 SER G CA   1 
ATOM   9382  C  C    . SER G 1 46  ? 4.040   -25.674 7.231   1.00 91.28  ? 253 SER G C    1 
ATOM   9383  O  O    . SER G 1 46  ? 5.192   -25.632 7.670   1.00 92.43  ? 253 SER G O    1 
ATOM   9384  C  CB   . SER G 1 46  ? 4.761   -25.343 4.849   1.00 90.01  ? 253 SER G CB   1 
ATOM   9385  O  OG   . SER G 1 46  ? 4.254   -25.281 3.526   1.00 92.55  ? 253 SER G OG   1 
ATOM   9386  N  N    . LYS G 1 47  ? 2.970   -25.412 7.977   1.00 91.47  ? 254 LYS G N    1 
ATOM   9387  C  CA   . LYS G 1 47  ? 3.031   -25.207 9.417   1.00 86.53  ? 254 LYS G CA   1 
ATOM   9388  C  C    . LYS G 1 47  ? 2.409   -26.382 10.172  1.00 87.76  ? 254 LYS G C    1 
ATOM   9389  O  O    . LYS G 1 47  ? 1.708   -26.201 11.168  1.00 81.99  ? 254 LYS G O    1 
ATOM   9390  N  N    . SER G 1 48  ? 2.653   -27.603 9.698   1.00 86.96  ? 255 SER G N    1 
ATOM   9391  C  CA   . SER G 1 48  ? 2.210   -28.818 10.373  1.00 82.93  ? 255 SER G CA   1 
ATOM   9392  C  C    . SER G 1 48  ? 3.416   -29.722 10.602  1.00 85.62  ? 255 SER G C    1 
ATOM   9393  O  O    . SER G 1 48  ? 4.150   -30.045 9.661   1.00 85.97  ? 255 SER G O    1 
ATOM   9394  C  CB   . SER G 1 48  ? 1.133   -29.538 9.558   1.00 85.37  ? 255 SER G CB   1 
ATOM   9395  O  OG   . SER G 1 48  ? 1.197   -30.944 9.731   1.00 79.67  ? 255 SER G OG   1 
ATOM   9396  N  N    . VAL G 1 49  ? 3.634   -30.116 11.856  1.00 84.83  ? 256 VAL G N    1 
ATOM   9397  C  CA   . VAL G 1 49  ? 4.723   -31.042 12.151  1.00 79.51  ? 256 VAL G CA   1 
ATOM   9398  C  C    . VAL G 1 49  ? 4.509   -32.395 11.474  1.00 81.83  ? 256 VAL G C    1 
ATOM   9399  O  O    . VAL G 1 49  ? 5.453   -32.905 10.856  1.00 82.42  ? 256 VAL G O    1 
ATOM   9400  C  CB   . VAL G 1 49  ? 4.926   -31.159 13.674  1.00 81.31  ? 256 VAL G CB   1 
ATOM   9401  C  CG1  . VAL G 1 49  ? 5.960   -32.221 13.986  1.00 74.79  ? 256 VAL G CG1  1 
ATOM   9402  C  CG2  . VAL G 1 49  ? 5.344   -29.813 14.272  1.00 82.77  ? 256 VAL G CG2  1 
ATOM   9403  N  N    . PRO G 1 50  ? 3.327   -33.012 11.543  1.00 81.90  ? 257 PRO G N    1 
ATOM   9404  C  CA   . PRO G 1 50  ? 3.163   -34.278 10.806  1.00 79.41  ? 257 PRO G CA   1 
ATOM   9405  C  C    . PRO G 1 50  ? 3.391   -34.124 9.307   1.00 80.30  ? 257 PRO G C    1 
ATOM   9406  O  O    . PRO G 1 50  ? 4.086   -34.950 8.701   1.00 79.27  ? 257 PRO G O    1 
ATOM   9407  C  CB   . PRO G 1 50  ? 1.722   -34.688 11.147  1.00 81.55  ? 257 PRO G CB   1 
ATOM   9408  C  CG   . PRO G 1 50  ? 1.052   -33.428 11.614  1.00 78.51  ? 257 PRO G CG   1 
ATOM   9409  C  CD   . PRO G 1 50  ? 2.119   -32.672 12.315  1.00 79.94  ? 257 PRO G CD   1 
ATOM   9410  N  N    . LEU G 1 51  ? 2.846   -33.063 8.700   1.00 84.25  ? 258 LEU G N    1 
ATOM   9411  C  CA   . LEU G 1 51  ? 3.083   -32.808 7.280   1.00 84.66  ? 258 LEU G CA   1 
ATOM   9412  C  C    . LEU G 1 51  ? 4.573   -32.700 6.976   1.00 87.06  ? 258 LEU G C    1 
ATOM   9413  O  O    . LEU G 1 51  ? 5.062   -33.283 5.998   1.00 88.21  ? 258 LEU G O    1 
ATOM   9414  C  CB   . LEU G 1 51  ? 2.354   -31.534 6.844   1.00 75.42  ? 258 LEU G CB   1 
ATOM   9415  N  N    . ALA G 1 52  ? 5.299   -32.010 7.841   1.00 83.27  ? 259 ALA G N    1 
ATOM   9416  C  CA   . ALA G 1 52  ? 6.744   -31.839 7.604   1.00 82.13  ? 259 ALA G CA   1 
ATOM   9417  C  C    . ALA G 1 52  ? 7.469   -33.170 7.810   1.00 80.78  ? 259 ALA G C    1 
ATOM   9418  O  O    . ALA G 1 52  ? 8.469   -33.397 7.127   1.00 77.32  ? 259 ALA G O    1 
ATOM   9419  C  CB   . ALA G 1 52  ? 7.258   -30.775 8.522   1.00 82.14  ? 259 ALA G CB   1 
ATOM   9420  N  N    . LEU G 1 53  ? 6.977   -34.002 8.725   1.00 80.64  ? 260 LEU G N    1 
ATOM   9421  C  CA   . LEU G 1 53  ? 7.588   -35.330 8.961   1.00 79.70  ? 260 LEU G CA   1 
ATOM   9422  C  C    . LEU G 1 53  ? 7.332   -36.187 7.725   1.00 84.80  ? 260 LEU G C    1 
ATOM   9423  O  O    . LEU G 1 53  ? 8.276   -36.837 7.289   1.00 79.16  ? 260 LEU G O    1 
ATOM   9424  C  CB   . LEU G 1 53  ? 6.989   -35.939 10.229  1.00 76.93  ? 260 LEU G CB   1 
ATOM   9425  C  CG   . LEU G 1 53  ? 7.673   -35.553 11.536  1.00 73.45  ? 260 LEU G CG   1 
ATOM   9426  C  CD1  . LEU G 1 53  ? 7.511   -36.655 12.564  1.00 73.46  ? 260 LEU G CD1  1 
ATOM   9427  C  CD2  . LEU G 1 53  ? 9.143   -35.258 11.307  1.00 80.45  ? 260 LEU G CD2  1 
ATOM   9428  N  N    . GLN G 1 54  ? 6.104   -36.196 7.195   1.00 87.29  ? 261 GLN G N    1 
ATOM   9429  C  CA   . GLN G 1 54  ? 5.854   -36.884 5.934   1.00 85.01  ? 261 GLN G CA   1 
ATOM   9430  C  C    . GLN G 1 54  ? 6.892   -36.470 4.900   1.00 83.07  ? 261 GLN G C    1 
ATOM   9431  O  O    . GLN G 1 54  ? 7.551   -37.317 4.283   1.00 82.17  ? 261 GLN G O    1 
ATOM   9432  N  N    . ARG G 1 55  ? 7.086   -35.158 4.740   1.00 79.85  ? 262 ARG G N    1 
ATOM   9433  C  CA   . ARG G 1 55  ? 8.023   -34.665 3.736   1.00 80.25  ? 262 ARG G CA   1 
ATOM   9434  C  C    . ARG G 1 55  ? 9.431   -35.187 4.000   1.00 82.31  ? 262 ARG G C    1 
ATOM   9435  O  O    . ARG G 1 55  ? 10.051  -35.794 3.122   1.00 81.48  ? 262 ARG G O    1 
ATOM   9436  C  CB   . ARG G 1 55  ? 8.002   -33.137 3.700   1.00 74.17  ? 262 ARG G CB   1 
ATOM   9437  N  N    . VAL G 1 56  ? 9.945   -34.970 5.215   1.00 85.85  ? 263 VAL G N    1 
ATOM   9438  C  CA   . VAL G 1 56  ? 11.287  -35.433 5.560   1.00 79.72  ? 263 VAL G CA   1 
ATOM   9439  C  C    . VAL G 1 56  ? 11.403  -36.931 5.329   1.00 81.93  ? 263 VAL G C    1 
ATOM   9440  O  O    . VAL G 1 56  ? 12.334  -37.405 4.663   1.00 81.50  ? 263 VAL G O    1 
ATOM   9441  C  CB   . VAL G 1 56  ? 11.623  -35.064 7.016   1.00 80.61  ? 263 VAL G CB   1 
ATOM   9442  C  CG1  . VAL G 1 56  ? 12.898  -35.768 7.469   1.00 69.28  ? 263 VAL G CG1  1 
ATOM   9443  C  CG2  . VAL G 1 56  ? 11.752  -33.562 7.154   1.00 83.58  ? 263 VAL G CG2  1 
ATOM   9444  N  N    . PHE G 1 57  ? 10.454  -37.698 5.875   1.00 84.40  ? 264 PHE G N    1 
ATOM   9445  C  CA   . PHE G 1 57  ? 10.486  -39.148 5.713   1.00 86.71  ? 264 PHE G CA   1 
ATOM   9446  C  C    . PHE G 1 57  ? 10.453  -39.550 4.241   1.00 88.87  ? 264 PHE G C    1 
ATOM   9447  O  O    . PHE G 1 57  ? 11.013  -40.589 3.875   1.00 89.59  ? 264 PHE G O    1 
ATOM   9448  C  CB   . PHE G 1 57  ? 9.322   -39.792 6.476   1.00 89.64  ? 264 PHE G CB   1 
ATOM   9449  C  CG   . PHE G 1 57  ? 9.560   -39.928 7.963   1.00 84.14  ? 264 PHE G CG   1 
ATOM   9450  C  CD1  . PHE G 1 57  ? 10.811  -39.684 8.506   1.00 83.70  ? 264 PHE G CD1  1 
ATOM   9451  C  CD2  . PHE G 1 57  ? 8.534   -40.301 8.810   1.00 77.41  ? 264 PHE G CD2  1 
ATOM   9452  C  CE1  . PHE G 1 57  ? 11.035  -39.811 9.867   1.00 80.04  ? 264 PHE G CE1  1 
ATOM   9453  C  CE2  . PHE G 1 57  ? 8.751   -40.428 10.161  1.00 81.80  ? 264 PHE G CE2  1 
ATOM   9454  C  CZ   . PHE G 1 57  ? 10.010  -40.187 10.689  1.00 81.18  ? 264 PHE G CZ   1 
ATOM   9455  N  N    . TYR G 1 58  ? 9.821   -38.740 3.383   1.00 86.95  ? 265 TYR G N    1 
ATOM   9456  C  CA   . TYR G 1 58  ? 9.859   -39.013 1.946   1.00 86.17  ? 265 TYR G CA   1 
ATOM   9457  C  C    . TYR G 1 58  ? 11.283  -38.903 1.407   1.00 89.67  ? 265 TYR G C    1 
ATOM   9458  O  O    . TYR G 1 58  ? 11.854  -39.889 0.925   1.00 89.26  ? 265 TYR G O    1 
ATOM   9459  C  CB   . TYR G 1 58  ? 8.919   -38.063 1.195   1.00 77.97  ? 265 TYR G CB   1 
ATOM   9460  N  N    . GLU G 1 59  ? 11.847  -37.697 1.472   1.00 89.27  ? 266 GLU G N    1 
ATOM   9461  C  CA   . GLU G 1 59  ? 13.220  -37.452 0.961   1.00 88.01  ? 266 GLU G CA   1 
ATOM   9462  C  C    . GLU G 1 59  ? 14.208  -38.459 1.552   1.00 91.39  ? 266 GLU G C    1 
ATOM   9463  O  O    . GLU G 1 59  ? 15.139  -38.846 0.830   1.00 97.90  ? 266 GLU G O    1 
ATOM   9464  N  N    . LEU G 1 60  ? 14.022  -38.862 2.809   1.00 91.36  ? 267 LEU G N    1 
ATOM   9465  C  CA   . LEU G 1 60  ? 14.912  -39.871 3.378   1.00 93.65  ? 267 LEU G CA   1 
ATOM   9466  C  C    . LEU G 1 60  ? 14.853  -41.176 2.588   1.00 96.09  ? 267 LEU G C    1 
ATOM   9467  O  O    . LEU G 1 60  ? 15.823  -41.948 2.586   1.00 97.88  ? 267 LEU G O    1 
ATOM   9468  N  N    . GLN G 1 61  ? 13.697  -41.483 2.000   1.00 92.71  ? 268 GLN G N    1 
ATOM   9469  C  CA   . GLN G 1 61  ? 13.534  -42.773 1.278   1.00 95.47  ? 268 GLN G CA   1 
ATOM   9470  C  C    . GLN G 1 61  ? 13.354  -42.489 -0.211  1.00 95.04  ? 268 GLN G C    1 
ATOM   9471  O  O    . GLN G 1 61  ? 12.468  -43.109 -0.819  1.00 93.88  ? 268 GLN G O    1 
ATOM   9472  N  N    . ASP G 1 64  ? 18.389  -38.685 -3.771  1.00 101.67 ? 271 ASP G N    1 
ATOM   9473  C  CA   . ASP G 1 64  ? 19.746  -39.222 -3.763  1.00 98.00  ? 271 ASP G CA   1 
ATOM   9474  C  C    . ASP G 1 64  ? 20.768  -38.250 -3.189  1.00 92.44  ? 271 ASP G C    1 
ATOM   9475  O  O    . ASP G 1 64  ? 21.921  -38.639 -2.986  1.00 80.89  ? 271 ASP G O    1 
ATOM   9476  N  N    . LYS G 1 65  ? 20.315  -37.036 -2.869  1.00 98.14  ? 272 LYS G N    1 
ATOM   9477  C  CA   . LYS G 1 65  ? 21.186  -35.995 -2.267  1.00 96.25  ? 272 LYS G CA   1 
ATOM   9478  C  C    . LYS G 1 65  ? 20.617  -35.627 -0.892  1.00 98.33  ? 272 LYS G C    1 
ATOM   9479  O  O    . LYS G 1 65  ? 19.427  -35.891 -0.670  1.00 95.59  ? 272 LYS G O    1 
ATOM   9480  C  CB   . LYS G 1 65  ? 21.238  -34.793 -3.211  1.00 92.80  ? 272 LYS G CB   1 
ATOM   9481  N  N    . PRO G 1 66  ? 21.396  -35.040 0.045   1.00 97.65  ? 273 PRO G N    1 
ATOM   9482  C  CA   . PRO G 1 66  ? 20.919  -34.765 1.419   1.00 94.32  ? 273 PRO G CA   1 
ATOM   9483  C  C    . PRO G 1 66  ? 19.532  -34.129 1.591   1.00 91.82  ? 273 PRO G C    1 
ATOM   9484  O  O    . PRO G 1 66  ? 19.105  -33.387 0.731   1.00 90.98  ? 273 PRO G O    1 
ATOM   9485  C  CB   . PRO G 1 66  ? 21.988  -33.804 1.941   1.00 91.83  ? 273 PRO G CB   1 
ATOM   9486  C  CG   . PRO G 1 66  ? 23.251  -34.299 1.288   1.00 96.79  ? 273 PRO G CG   1 
ATOM   9487  C  CD   . PRO G 1 66  ? 22.809  -34.672 -0.110  1.00 94.68  ? 273 PRO G CD   1 
ATOM   9488  N  N    . VAL G 1 67  ? 18.883  -34.408 2.722   1.00 89.22  ? 274 VAL G N    1 
ATOM   9489  C  CA   . VAL G 1 67  ? 17.485  -33.923 2.930   1.00 90.00  ? 274 VAL G CA   1 
ATOM   9490  C  C    . VAL G 1 67  ? 17.471  -32.651 3.785   1.00 87.69  ? 274 VAL G C    1 
ATOM   9491  O  O    . VAL G 1 67  ? 18.248  -32.571 4.743   1.00 82.85  ? 274 VAL G O    1 
ATOM   9492  C  CB   . VAL G 1 67  ? 16.601  -35.029 3.534   1.00 87.19  ? 274 VAL G CB   1 
ATOM   9493  C  CG1  . VAL G 1 67  ? 15.122  -34.775 3.290   1.00 83.40  ? 274 VAL G CG1  1 
ATOM   9494  C  CG2  . VAL G 1 67  ? 16.993  -36.410 3.038   1.00 83.89  ? 274 VAL G CG2  1 
ATOM   9495  N  N    . GLY G 1 68  ? 16.583  -31.712 3.453   1.00 91.57  ? 275 GLY G N    1 
ATOM   9496  C  CA   . GLY G 1 68  ? 16.512  -30.428 4.168   1.00 82.14  ? 275 GLY G CA   1 
ATOM   9497  C  C    . GLY G 1 68  ? 15.434  -30.419 5.221   1.00 84.35  ? 275 GLY G C    1 
ATOM   9498  O  O    . GLY G 1 68  ? 14.256  -30.541 4.855   1.00 89.52  ? 275 GLY G O    1 
ATOM   9499  N  N    . THR G 1 69  ? 15.827  -30.258 6.478   1.00 80.65  ? 276 THR G N    1 
ATOM   9500  C  CA   . THR G 1 69  ? 14.891  -30.216 7.597   1.00 77.24  ? 276 THR G CA   1 
ATOM   9501  C  C    . THR G 1 69  ? 14.257  -28.843 7.785   1.00 78.73  ? 276 THR G C    1 
ATOM   9502  O  O    . THR G 1 69  ? 13.555  -28.617 8.780   1.00 76.66  ? 276 THR G O    1 
ATOM   9503  C  CB   . THR G 1 69  ? 15.599  -30.645 8.885   1.00 77.38  ? 276 THR G CB   1 
ATOM   9504  O  OG1  . THR G 1 69  ? 16.888  -30.014 8.985   1.00 79.85  ? 276 THR G OG1  1 
ATOM   9505  C  CG2  . THR G 1 69  ? 15.790  -32.130 8.886   1.00 76.67  ? 276 THR G CG2  1 
ATOM   9506  N  N    . LYS G 1 70  ? 14.476  -27.946 6.826   1.00 78.86  ? 277 LYS G N    1 
ATOM   9507  C  CA   . LYS G 1 70  ? 14.077  -26.553 6.965   1.00 75.66  ? 277 LYS G CA   1 
ATOM   9508  C  C    . LYS G 1 70  ? 12.577  -26.417 7.227   1.00 79.79  ? 277 LYS G C    1 
ATOM   9509  O  O    . LYS G 1 70  ? 12.162  -25.706 8.148   1.00 78.80  ? 277 LYS G O    1 
ATOM   9510  C  CB   . LYS G 1 70  ? 14.491  -25.810 5.699   1.00 83.44  ? 277 LYS G CB   1 
ATOM   9511  C  CG   . LYS G 1 70  ? 14.627  -26.762 4.487   1.00 82.83  ? 277 LYS G CG   1 
ATOM   9512  C  CD   . LYS G 1 70  ? 15.074  -26.028 3.231   1.00 88.77  ? 277 LYS G CD   1 
ATOM   9513  C  CE   . LYS G 1 70  ? 15.829  -26.958 2.304   1.00 76.82  ? 277 LYS G CE   1 
ATOM   9514  N  NZ   . LYS G 1 70  ? 17.234  -27.145 2.747   1.00 81.63  ? 277 LYS G NZ   1 
ATOM   9515  N  N    . LYS G 1 71  ? 11.744  -27.102 6.432   1.00 83.36  ? 278 LYS G N    1 
ATOM   9516  C  CA   . LYS G 1 71  ? 10.291  -26.975 6.560   1.00 81.24  ? 278 LYS G CA   1 
ATOM   9517  C  C    . LYS G 1 71  ? 9.757   -27.520 7.883   1.00 81.21  ? 278 LYS G C    1 
ATOM   9518  O  O    . LYS G 1 71  ? 8.650   -27.149 8.293   1.00 81.55  ? 278 LYS G O    1 
ATOM   9519  N  N    . LEU G 1 72  ? 10.514  -28.388 8.557   1.00 81.28  ? 279 LEU G N    1 
ATOM   9520  C  CA   . LEU G 1 72  ? 10.089  -28.886 9.863   1.00 79.69  ? 279 LEU G CA   1 
ATOM   9521  C  C    . LEU G 1 72  ? 10.320  -27.854 10.968  1.00 80.23  ? 279 LEU G C    1 
ATOM   9522  O  O    . LEU G 1 72  ? 9.384   -27.504 11.699  1.00 76.40  ? 279 LEU G O    1 
ATOM   9523  C  CB   . LEU G 1 72  ? 10.804  -30.202 10.185  1.00 72.16  ? 279 LEU G CB   1 
ATOM   9524  C  CG   . LEU G 1 72  ? 10.515  -30.792 11.566  1.00 73.68  ? 279 LEU G CG   1 
ATOM   9525  C  CD1  . LEU G 1 72  ? 9.043   -31.218 11.708  1.00 79.22  ? 279 LEU G CD1  1 
ATOM   9526  C  CD2  . LEU G 1 72  ? 11.455  -31.957 11.831  1.00 73.47  ? 279 LEU G CD2  1 
ATOM   9527  N  N    . THR G 1 73  ? 11.562  -27.364 11.122  1.00 77.52  ? 280 THR G N    1 
ATOM   9528  C  CA   . THR G 1 73  ? 11.807  -26.343 12.140  1.00 74.41  ? 280 THR G CA   1 
ATOM   9529  C  C    . THR G 1 73  ? 10.934  -25.121 11.890  1.00 73.79  ? 280 THR G C    1 
ATOM   9530  O  O    . THR G 1 73  ? 10.415  -24.514 12.834  1.00 75.51  ? 280 THR G O    1 
ATOM   9531  C  CB   . THR G 1 73  ? 13.292  -25.962 12.201  1.00 65.42  ? 280 THR G CB   1 
ATOM   9532  O  OG1  . THR G 1 73  ? 13.844  -25.881 10.886  1.00 69.67  ? 280 THR G OG1  1 
ATOM   9533  C  CG2  . THR G 1 73  ? 14.079  -26.981 12.983  1.00 61.44  ? 280 THR G CG2  1 
ATOM   9534  N  N    . LYS G 1 74  ? 10.728  -24.771 10.621  1.00 72.30  ? 281 LYS G N    1 
ATOM   9535  C  CA   . LYS G 1 74  ? 9.699   -23.796 10.277  1.00 76.20  ? 281 LYS G CA   1 
ATOM   9536  C  C    . LYS G 1 74  ? 8.354   -24.200 10.868  1.00 80.41  ? 281 LYS G C    1 
ATOM   9537  O  O    . LYS G 1 74  ? 7.664   -23.388 11.494  1.00 81.74  ? 281 LYS G O    1 
ATOM   9538  N  N    . SER G 1 75  ? 7.973   -25.469 10.698  1.00 84.21  ? 282 SER G N    1 
ATOM   9539  C  CA   . SER G 1 75  ? 6.706   -25.933 11.256  1.00 78.72  ? 282 SER G CA   1 
ATOM   9540  C  C    . SER G 1 75  ? 6.700   -25.823 12.773  1.00 79.86  ? 282 SER G C    1 
ATOM   9541  O  O    . SER G 1 75  ? 5.655   -25.564 13.378  1.00 82.62  ? 282 SER G O    1 
ATOM   9542  C  CB   . SER G 1 75  ? 6.442   -27.372 10.820  1.00 81.97  ? 282 SER G CB   1 
ATOM   9543  O  OG   . SER G 1 75  ? 5.557   -27.999 11.719  1.00 84.87  ? 282 SER G OG   1 
ATOM   9544  N  N    . PHE G 1 76  ? 7.861   -25.993 13.401  1.00 81.43  ? 283 PHE G N    1 
ATOM   9545  C  CA   . PHE G 1 76  ? 7.994   -25.841 14.843  1.00 80.73  ? 283 PHE G CA   1 
ATOM   9546  C  C    . PHE G 1 76  ? 7.721   -24.427 15.328  1.00 81.72  ? 283 PHE G C    1 
ATOM   9547  O  O    . PHE G 1 76  ? 7.630   -24.225 16.543  1.00 82.86  ? 283 PHE G O    1 
ATOM   9548  C  CB   . PHE G 1 76  ? 9.402   -26.230 15.292  1.00 76.63  ? 283 PHE G CB   1 
ATOM   9549  C  CG   . PHE G 1 76  ? 9.668   -27.692 15.233  1.00 77.66  ? 283 PHE G CG   1 
ATOM   9550  C  CD1  . PHE G 1 76  ? 8.636   -28.587 15.013  1.00 79.49  ? 283 PHE G CD1  1 
ATOM   9551  C  CD2  . PHE G 1 76  ? 10.948  -28.180 15.408  1.00 77.04  ? 283 PHE G CD2  1 
ATOM   9552  C  CE1  . PHE G 1 76  ? 8.881   -29.946 14.962  1.00 77.87  ? 283 PHE G CE1  1 
ATOM   9553  C  CE2  . PHE G 1 76  ? 11.195  -29.540 15.352  1.00 77.82  ? 283 PHE G CE2  1 
ATOM   9554  C  CZ   . PHE G 1 76  ? 10.162  -30.421 15.128  1.00 71.71  ? 283 PHE G CZ   1 
ATOM   9555  N  N    . GLY G 1 77  ? 7.620   -23.452 14.431  1.00 77.84  ? 284 GLY G N    1 
ATOM   9556  C  CA   . GLY G 1 77  ? 7.500   -22.068 14.840  1.00 78.84  ? 284 GLY G CA   1 
ATOM   9557  C  C    . GLY G 1 77  ? 8.804   -21.365 15.144  1.00 75.49  ? 284 GLY G C    1 
ATOM   9558  O  O    . GLY G 1 77  ? 8.792   -20.382 15.895  1.00 79.34  ? 284 GLY G O    1 
ATOM   9559  N  N    . TRP G 1 78  ? 9.891   -21.850 14.548  1.00 77.16  ? 285 TRP G N    1 
ATOM   9560  C  CA   . TRP G 1 78  ? 11.238  -21.317 14.856  1.00 78.81  ? 285 TRP G CA   1 
ATOM   9561  C  C    . TRP G 1 78  ? 11.756  -20.416 13.743  1.00 79.66  ? 285 TRP G C    1 
ATOM   9562  O  O    . TRP G 1 78  ? 11.260  -20.533 12.613  1.00 82.29  ? 285 TRP G O    1 
ATOM   9563  C  CB   . TRP G 1 78  ? 12.203  -22.487 15.011  1.00 73.66  ? 285 TRP G CB   1 
ATOM   9564  C  CG   . TRP G 1 78  ? 12.052  -23.319 16.241  1.00 72.96  ? 285 TRP G CG   1 
ATOM   9565  C  CD1  . TRP G 1 78  ? 11.095  -23.235 17.208  1.00 75.02  ? 285 TRP G CD1  1 
ATOM   9566  C  CD2  . TRP G 1 78  ? 12.925  -24.387 16.628  1.00 72.14  ? 285 TRP G CD2  1 
ATOM   9567  N  NE1  . TRP G 1 78  ? 11.314  -24.183 18.170  1.00 80.32  ? 285 TRP G NE1  1 
ATOM   9568  C  CE2  . TRP G 1 78  ? 12.431  -24.902 17.841  1.00 70.78  ? 285 TRP G CE2  1 
ATOM   9569  C  CE3  . TRP G 1 78  ? 14.076  -24.947 16.070  1.00 70.94  ? 285 TRP G CE3  1 
ATOM   9570  C  CZ2  . TRP G 1 78  ? 13.056  -25.953 18.502  1.00 71.31  ? 285 TRP G CZ2  1 
ATOM   9571  C  CZ3  . TRP G 1 78  ? 14.688  -25.991 16.722  1.00 72.86  ? 285 TRP G CZ3  1 
ATOM   9572  C  CH2  . TRP G 1 78  ? 14.180  -26.488 17.920  1.00 67.40  ? 285 TRP G CH2  1 
ATOM   9573  N  N    . GLU G 1 79  ? 12.726  -19.556 14.058  1.00 79.20  ? 286 GLU G N    1 
ATOM   9574  C  CA   . GLU G 1 79  ? 13.396  -18.744 13.012  1.00 75.92  ? 286 GLU G CA   1 
ATOM   9575  C  C    . GLU G 1 79  ? 14.767  -19.367 12.759  1.00 72.62  ? 286 GLU G C    1 
ATOM   9576  O  O    . GLU G 1 79  ? 15.075  -20.401 13.377  1.00 76.75  ? 286 GLU G O    1 
ATOM   9577  C  CB   . GLU G 1 79  ? 13.556  -17.303 13.475  1.00 79.82  ? 286 GLU G CB   1 
ATOM   9578  C  CG   . GLU G 1 79  ? 12.242  -16.574 13.675  1.00 77.28  ? 286 GLU G CG   1 
ATOM   9579  C  CD   . GLU G 1 79  ? 11.556  -16.145 12.391  1.00 83.38  ? 286 GLU G CD   1 
ATOM   9580  O  OE1  . GLU G 1 79  ? 10.325  -16.298 12.308  1.00 90.51  ? 286 GLU G OE1  1 
ATOM   9581  O  OE2  . GLU G 1 79  ? 12.253  -15.660 11.479  1.00 84.94  ? 286 GLU G OE2  1 
ATOM   9582  N  N    . THR G 1 80  ? 15.562  -18.769 11.881  1.00 70.90  ? 287 THR G N    1 
ATOM   9583  C  CA   . THR G 1 80  ? 16.872  -19.377 11.536  1.00 65.32  ? 287 THR G CA   1 
ATOM   9584  C  C    . THR G 1 80  ? 17.706  -19.504 12.809  1.00 66.88  ? 287 THR G C    1 
ATOM   9585  O  O    . THR G 1 80  ? 18.239  -20.587 13.038  1.00 70.52  ? 287 THR G O    1 
ATOM   9586  C  CB   . THR G 1 80  ? 17.562  -18.578 10.426  1.00 66.64  ? 287 THR G CB   1 
ATOM   9587  O  OG1  . THR G 1 80  ? 16.692  -18.547 9.295   1.00 68.03  ? 287 THR G OG1  1 
ATOM   9588  C  CG2  . THR G 1 80  ? 18.892  -19.164 10.010  1.00 65.97  ? 287 THR G CG2  1 
ATOM   9589  N  N    . LEU G 1 81  ? 17.776  -18.449 13.613  1.00 69.89  ? 288 LEU G N    1 
ATOM   9590  C  CA   . LEU G 1 81  ? 18.549  -18.435 14.885  1.00 68.45  ? 288 LEU G CA   1 
ATOM   9591  C  C    . LEU G 1 81  ? 18.250  -19.673 15.724  1.00 64.62  ? 288 LEU G C    1 
ATOM   9592  O  O    . LEU G 1 81  ? 19.191  -20.253 16.250  1.00 63.05  ? 288 LEU G O    1 
ATOM   9593  C  CB   . LEU G 1 81  ? 18.129  -17.162 15.626  1.00 65.08  ? 288 LEU G CB   1 
ATOM   9594  C  CG   . LEU G 1 81  ? 18.710  -16.923 17.015  1.00 63.64  ? 288 LEU G CG   1 
ATOM   9595  C  CD1  . LEU G 1 81  ? 19.285  -15.522 17.102  1.00 61.47  ? 288 LEU G CD1  1 
ATOM   9596  C  CD2  . LEU G 1 81  ? 17.645  -17.108 18.085  1.00 65.67  ? 288 LEU G CD2  1 
ATOM   9597  N  N    . ASP G 1 82  ? 16.978  -20.023 15.867  1.00 69.56  ? 289 ASP G N    1 
ATOM   9598  C  CA   . ASP G 1 82  ? 16.580  -21.148 16.746  1.00 67.22  ? 289 ASP G CA   1 
ATOM   9599  C  C    . ASP G 1 82  ? 17.233  -22.441 16.262  1.00 68.01  ? 289 ASP G C    1 
ATOM   9600  O  O    . ASP G 1 82  ? 17.458  -23.326 17.097  1.00 64.02  ? 289 ASP G O    1 
ATOM   9601  C  CB   . ASP G 1 82  ? 15.058  -21.227 16.844  1.00 67.08  ? 289 ASP G CB   1 
ATOM   9602  C  CG   . ASP G 1 82  ? 14.403  -19.949 17.325  1.00 73.28  ? 289 ASP G CG   1 
ATOM   9603  O  OD1  . ASP G 1 82  ? 14.330  -18.996 16.534  1.00 78.20  ? 289 ASP G OD1  1 
ATOM   9604  O  OD2  . ASP G 1 82  ? 13.963  -19.923 18.486  1.00 80.18  ? 289 ASP G OD2  1 
ATOM   9605  N  N    . SER G 1 83  ? 17.517  -22.549 14.968  1.00 61.13  ? 290 SER G N    1 
ATOM   9606  C  CA   . SER G 1 83  ? 18.233  -23.738 14.527  1.00 66.92  ? 290 SER G CA   1 
ATOM   9607  C  C    . SER G 1 83  ? 19.734  -23.637 14.740  1.00 69.58  ? 290 SER G C    1 
ATOM   9608  O  O    . SER G 1 83  ? 20.473  -24.448 14.170  1.00 75.31  ? 290 SER G O    1 
ATOM   9609  C  CB   . SER G 1 83  ? 17.939  -24.046 13.055  1.00 69.90  ? 290 SER G CB   1 
ATOM   9610  O  OG   . SER G 1 83  ? 16.575  -23.801 12.742  1.00 72.78  ? 290 SER G OG   1 
ATOM   9611  N  N    . PHE G 1 84  ? 20.207  -22.681 15.545  1.00 69.64  ? 291 PHE G N    1 
ATOM   9612  C  CA   . PHE G 1 84  ? 21.608  -22.633 15.952  1.00 68.27  ? 291 PHE G CA   1 
ATOM   9613  C  C    . PHE G 1 84  ? 21.780  -22.860 17.450  1.00 67.52  ? 291 PHE G C    1 
ATOM   9614  O  O    . PHE G 1 84  ? 22.884  -22.662 17.978  1.00 63.97  ? 291 PHE G O    1 
ATOM   9615  C  CB   . PHE G 1 84  ? 22.245  -21.310 15.528  1.00 68.51  ? 291 PHE G CB   1 
ATOM   9616  C  CG   . PHE G 1 84  ? 22.510  -21.224 14.067  1.00 64.84  ? 291 PHE G CG   1 
ATOM   9617  C  CD1  . PHE G 1 84  ? 21.458  -21.110 13.168  1.00 71.57  ? 291 PHE G CD1  1 
ATOM   9618  C  CD2  . PHE G 1 84  ? 23.808  -21.272 13.579  1.00 67.77  ? 291 PHE G CD2  1 
ATOM   9619  C  CE1  . PHE G 1 84  ? 21.697  -21.041 11.798  1.00 71.15  ? 291 PHE G CE1  1 
ATOM   9620  C  CE2  . PHE G 1 84  ? 24.057  -21.210 12.216  1.00 67.59  ? 291 PHE G CE2  1 
ATOM   9621  C  CZ   . PHE G 1 84  ? 22.996  -21.093 11.323  1.00 70.41  ? 291 PHE G CZ   1 
ATOM   9622  N  N    . MET G 1 85  ? 20.716  -23.276 18.138  1.00 67.44  ? 292 MET G N    1 
ATOM   9623  C  CA   . MET G 1 85  ? 20.788  -23.710 19.525  1.00 59.35  ? 292 MET G CA   1 
ATOM   9624  C  C    . MET G 1 85  ? 20.981  -25.221 19.589  1.00 61.82  ? 292 MET G C    1 
ATOM   9625  O  O    . MET G 1 85  ? 20.390  -25.970 18.806  1.00 66.26  ? 292 MET G O    1 
ATOM   9626  C  CB   . MET G 1 85  ? 19.521  -23.308 20.275  1.00 60.08  ? 292 MET G CB   1 
ATOM   9627  C  CG   . MET G 1 85  ? 19.229  -21.823 20.204  1.00 69.97  ? 292 MET G CG   1 
ATOM   9628  S  SD   . MET G 1 85  ? 20.146  -20.913 21.465  1.00 72.46  ? 292 MET G SD   1 
ATOM   9629  C  CE   . MET G 1 85  ? 19.330  -21.542 22.942  1.00 63.66  ? 292 MET G CE   1 
ATOM   9630  N  N    . GLN G 1 86  ? 21.812  -25.659 20.523  1.00 56.71  ? 293 GLN G N    1 
ATOM   9631  C  CA   . GLN G 1 86  ? 22.118  -27.065 20.692  1.00 62.18  ? 293 GLN G CA   1 
ATOM   9632  C  C    . GLN G 1 86  ? 21.187  -27.684 21.733  1.00 65.80  ? 293 GLN G C    1 
ATOM   9633  O  O    . GLN G 1 86  ? 20.746  -27.023 22.679  1.00 62.94  ? 293 GLN G O    1 
ATOM   9634  C  CB   . GLN G 1 86  ? 23.586  -27.251 21.090  1.00 62.67  ? 293 GLN G CB   1 
ATOM   9635  C  CG   . GLN G 1 86  ? 24.581  -26.826 20.006  1.00 63.93  ? 293 GLN G CG   1 
ATOM   9636  C  CD   . GLN G 1 86  ? 26.044  -27.066 20.391  1.00 66.42  ? 293 GLN G CD   1 
ATOM   9637  O  OE1  . GLN G 1 86  ? 26.382  -28.065 21.026  1.00 63.87  ? 293 GLN G OE1  1 
ATOM   9638  N  NE2  . GLN G 1 86  ? 26.916  -26.137 20.007  1.00 70.17  ? 293 GLN G NE2  1 
ATOM   9639  N  N    . HIS G 1 87  ? 20.900  -28.973 21.559  1.00 64.04  ? 294 HIS G N    1 
ATOM   9640  C  CA   . HIS G 1 87  ? 19.788  -29.557 22.279  1.00 59.17  ? 294 HIS G CA   1 
ATOM   9641  C  C    . HIS G 1 87  ? 20.027  -31.031 22.581  1.00 66.98  ? 294 HIS G C    1 
ATOM   9642  O  O    . HIS G 1 87  ? 20.822  -31.719 21.924  1.00 64.99  ? 294 HIS G O    1 
ATOM   9643  C  CB   . HIS G 1 87  ? 18.485  -29.374 21.497  1.00 64.71  ? 294 HIS G CB   1 
ATOM   9644  C  CG   . HIS G 1 87  ? 17.862  -28.024 21.677  1.00 62.00  ? 294 HIS G CG   1 
ATOM   9645  N  ND1  . HIS G 1 87  ? 17.539  -27.201 20.621  1.00 62.54  ? 294 HIS G ND1  1 
ATOM   9646  C  CD2  . HIS G 1 87  ? 17.515  -27.349 22.796  1.00 59.05  ? 294 HIS G CD2  1 
ATOM   9647  C  CE1  . HIS G 1 87  ? 17.025  -26.076 21.077  1.00 57.81  ? 294 HIS G CE1  1 
ATOM   9648  N  NE2  . HIS G 1 87  ? 16.999  -26.142 22.395  1.00 60.00  ? 294 HIS G NE2  1 
ATOM   9649  N  N    . ASP G 1 88  ? 19.306  -31.489 23.608  1.00 65.57  ? 295 ASP G N    1 
ATOM   9650  C  CA   . ASP G 1 88  ? 19.267  -32.877 24.038  1.00 58.90  ? 295 ASP G CA   1 
ATOM   9651  C  C    . ASP G 1 88  ? 18.368  -33.677 23.105  1.00 63.28  ? 295 ASP G C    1 
ATOM   9652  O  O    . ASP G 1 88  ? 17.198  -33.328 22.910  1.00 61.77  ? 295 ASP G O    1 
ATOM   9653  C  CB   . ASP G 1 88  ? 18.747  -32.945 25.470  1.00 62.05  ? 295 ASP G CB   1 
ATOM   9654  C  CG   . ASP G 1 88  ? 18.837  -34.326 26.052  1.00 61.84  ? 295 ASP G CG   1 
ATOM   9655  O  OD1  . ASP G 1 88  ? 18.121  -35.227 25.558  1.00 59.76  ? 295 ASP G OD1  1 
ATOM   9656  O  OD2  . ASP G 1 88  ? 19.631  -34.502 27.001  1.00 60.72  ? 295 ASP G OD2  1 
ATOM   9657  N  N    . VAL G 1 89  ? 18.905  -34.751 22.526  1.00 61.31  ? 296 VAL G N    1 
ATOM   9658  C  CA   . VAL G 1 89  ? 18.102  -35.517 21.582  1.00 64.56  ? 296 VAL G CA   1 
ATOM   9659  C  C    . VAL G 1 89  ? 16.921  -36.174 22.298  1.00 61.17  ? 296 VAL G C    1 
ATOM   9660  O  O    . VAL G 1 89  ? 15.802  -36.229 21.767  1.00 52.49  ? 296 VAL G O    1 
ATOM   9661  C  CB   . VAL G 1 89  ? 18.991  -36.527 20.823  1.00 65.90  ? 296 VAL G CB   1 
ATOM   9662  C  CG1  . VAL G 1 89  ? 19.568  -37.610 21.751  1.00 59.69  ? 296 VAL G CG1  1 
ATOM   9663  C  CG2  . VAL G 1 89  ? 18.219  -37.129 19.658  1.00 60.90  ? 296 VAL G CG2  1 
ATOM   9664  N  N    . GLN G 1 90  ? 17.132  -36.621 23.540  1.00 61.53  ? 297 GLN G N    1 
ATOM   9665  C  CA   . GLN G 1 90  ? 16.071  -37.318 24.260  1.00 66.13  ? 297 GLN G CA   1 
ATOM   9666  C  C    . GLN G 1 90  ? 14.962  -36.360 24.677  1.00 62.06  ? 297 GLN G C    1 
ATOM   9667  O  O    . GLN G 1 90  ? 13.812  -36.771 24.841  1.00 60.17  ? 297 GLN G O    1 
ATOM   9668  C  CB   . GLN G 1 90  ? 16.657  -38.048 25.471  1.00 59.51  ? 297 GLN G CB   1 
ATOM   9669  C  CG   . GLN G 1 90  ? 15.680  -38.924 26.214  1.00 61.01  ? 297 GLN G CG   1 
ATOM   9670  C  CD   . GLN G 1 90  ? 14.944  -38.163 27.295  1.00 64.63  ? 297 GLN G CD   1 
ATOM   9671  O  OE1  . GLN G 1 90  ? 15.466  -37.197 27.840  1.00 62.38  ? 297 GLN G OE1  1 
ATOM   9672  N  NE2  . GLN G 1 90  ? 13.721  -38.585 27.600  1.00 60.71  ? 297 GLN G NE2  1 
ATOM   9673  N  N    . GLU G 1 91  ? 15.275  -35.081 24.844  1.00 65.97  ? 298 GLU G N    1 
ATOM   9674  C  CA   . GLU G 1 91  ? 14.201  -34.129 25.086  1.00 67.10  ? 298 GLU G CA   1 
ATOM   9675  C  C    . GLU G 1 91  ? 13.353  -33.949 23.833  1.00 65.90  ? 298 GLU G C    1 
ATOM   9676  O  O    . GLU G 1 91  ? 12.118  -33.897 23.917  1.00 63.84  ? 298 GLU G O    1 
ATOM   9677  C  CB   . GLU G 1 91  ? 14.772  -32.796 25.565  1.00 61.08  ? 298 GLU G CB   1 
ATOM   9678  C  CG   . GLU G 1 91  ? 13.711  -31.752 25.911  1.00 61.17  ? 298 GLU G CG   1 
ATOM   9679  C  CD   . GLU G 1 91  ? 14.317  -30.495 26.529  1.00 57.85  ? 298 GLU G CD   1 
ATOM   9680  O  OE1  . GLU G 1 91  ? 13.560  -29.661 27.068  1.00 62.69  ? 298 GLU G OE1  1 
ATOM   9681  O  OE2  . GLU G 1 91  ? 15.555  -30.362 26.511  1.00 53.36  ? 298 GLU G OE2  1 
ATOM   9682  N  N    . LEU G 1 92  ? 13.999  -33.876 22.659  1.00 64.08  ? 299 LEU G N    1 
ATOM   9683  C  CA   . LEU G 1 92  ? 13.251  -33.729 21.416  1.00 63.30  ? 299 LEU G CA   1 
ATOM   9684  C  C    . LEU G 1 92  ? 12.370  -34.946 21.171  1.00 63.29  ? 299 LEU G C    1 
ATOM   9685  O  O    . LEU G 1 92  ? 11.206  -34.816 20.758  1.00 59.89  ? 299 LEU G O    1 
ATOM   9686  C  CB   . LEU G 1 92  ? 14.203  -33.506 20.238  1.00 64.49  ? 299 LEU G CB   1 
ATOM   9687  C  CG   . LEU G 1 92  ? 13.502  -33.344 18.880  1.00 63.85  ? 299 LEU G CG   1 
ATOM   9688  C  CD1  . LEU G 1 92  ? 12.514  -32.187 18.900  1.00 62.36  ? 299 LEU G CD1  1 
ATOM   9689  C  CD2  . LEU G 1 92  ? 14.503  -33.160 17.761  1.00 72.18  ? 299 LEU G CD2  1 
ATOM   9690  N  N    . CYS G 1 93  ? 12.899  -36.137 21.450  1.00 57.17  ? 300 CYS G N    1 
ATOM   9691  C  CA   . CYS G 1 93  ? 12.129  -37.353 21.222  1.00 65.31  ? 300 CYS G CA   1 
ATOM   9692  C  C    . CYS G 1 93  ? 10.814  -37.337 22.001  1.00 61.80  ? 300 CYS G C    1 
ATOM   9693  O  O    . CYS G 1 93  ? 9.754   -37.654 21.452  1.00 59.32  ? 300 CYS G O    1 
ATOM   9694  C  CB   . CYS G 1 93  ? 12.974  -38.578 21.589  1.00 63.40  ? 300 CYS G CB   1 
ATOM   9695  S  SG   . CYS G 1 93  ? 12.204  -40.163 21.130  1.00 62.43  ? 300 CYS G SG   1 
ATOM   9696  N  N    . ARG G 1 94  ? 10.871  -36.976 23.287  1.00 60.94  ? 301 ARG G N    1 
ATOM   9697  C  CA   . ARG G 1 94  ? 9.666   -36.901 24.108  1.00 57.68  ? 301 ARG G CA   1 
ATOM   9698  C  C    . ARG G 1 94  ? 8.663   -35.908 23.535  1.00 66.23  ? 301 ARG G C    1 
ATOM   9699  O  O    . ARG G 1 94  ? 7.476   -36.226 23.374  1.00 68.70  ? 301 ARG G O    1 
ATOM   9700  C  CB   . ARG G 1 94  ? 10.012  -36.507 25.550  1.00 60.25  ? 301 ARG G CB   1 
ATOM   9701  C  CG   . ARG G 1 94  ? 10.952  -37.439 26.349  1.00 60.57  ? 301 ARG G CG   1 
ATOM   9702  C  CD   . ARG G 1 94  ? 10.196  -38.517 27.100  1.00 53.81  ? 301 ARG G CD   1 
ATOM   9703  N  NE   . ARG G 1 94  ? 9.308   -39.200 26.171  1.00 60.98  ? 301 ARG G NE   1 
ATOM   9704  C  CZ   . ARG G 1 94  ? 9.703   -40.124 25.301  1.00 59.56  ? 301 ARG G CZ   1 
ATOM   9705  N  NH1  . ARG G 1 94  ? 10.973  -40.515 25.258  1.00 57.01  ? 301 ARG G NH1  1 
ATOM   9706  N  NH2  . ARG G 1 94  ? 8.819   -40.650 24.472  1.00 60.73  ? 301 ARG G NH2  1 
ATOM   9707  N  N    . VAL G 1 95  ? 9.113   -34.690 23.244  1.00 62.15  ? 302 VAL G N    1 
ATOM   9708  C  CA   . VAL G 1 95  ? 8.166   -33.643 22.764  1.00 59.55  ? 302 VAL G CA   1 
ATOM   9709  C  C    . VAL G 1 95  ? 7.639   -34.035 21.383  1.00 63.21  ? 302 VAL G C    1 
ATOM   9710  O  O    . VAL G 1 95  ? 6.441   -33.854 21.148  1.00 67.15  ? 302 VAL G O    1 
ATOM   9711  C  CB   . VAL G 1 95  ? 8.819   -32.250 22.761  1.00 60.91  ? 302 VAL G CB   1 
ATOM   9712  C  CG1  . VAL G 1 95  ? 7.871   -31.166 22.274  1.00 57.90  ? 302 VAL G CG1  1 
ATOM   9713  C  CG2  . VAL G 1 95  ? 9.370   -31.891 24.129  1.00 59.24  ? 302 VAL G CG2  1 
ATOM   9714  N  N    . LEU G 1 96  ? 8.496   -34.577 20.518  1.00 63.65  ? 303 LEU G N    1 
ATOM   9715  C  CA   . LEU G 1 96  ? 8.066   -34.915 19.133  1.00 68.23  ? 303 LEU G CA   1 
ATOM   9716  C  C    . LEU G 1 96  ? 7.113   -36.110 19.172  1.00 69.14  ? 303 LEU G C    1 
ATOM   9717  O  O    . LEU G 1 96  ? 6.033   -36.018 18.579  1.00 66.49  ? 303 LEU G O    1 
ATOM   9718  C  CB   . LEU G 1 96  ? 9.282   -35.236 18.262  1.00 68.79  ? 303 LEU G CB   1 
ATOM   9719  C  CG   . LEU G 1 96  ? 8.992   -35.600 16.809  1.00 67.78  ? 303 LEU G CG   1 
ATOM   9720  C  CD1  . LEU G 1 96  ? 8.296   -34.455 16.096  1.00 67.81  ? 303 LEU G CD1  1 
ATOM   9721  C  CD2  . LEU G 1 96  ? 10.277  -35.961 16.089  1.00 64.94  ? 303 LEU G CD2  1 
ATOM   9722  N  N    . LEU G 1 97  ? 7.519   -37.185 19.842  1.00 66.23  ? 304 LEU G N    1 
ATOM   9723  C  CA   . LEU G 1 97  ? 6.655   -38.360 19.911  1.00 67.22  ? 304 LEU G CA   1 
ATOM   9724  C  C    . LEU G 1 97  ? 5.312   -38.021 20.524  1.00 70.56  ? 304 LEU G C    1 
ATOM   9725  O  O    . LEU G 1 97  ? 4.296   -38.613 20.146  1.00 73.07  ? 304 LEU G O    1 
ATOM   9726  C  CB   . LEU G 1 97  ? 7.319   -39.478 20.712  1.00 63.01  ? 304 LEU G CB   1 
ATOM   9727  C  CG   . LEU G 1 97  ? 8.343   -40.279 19.910  1.00 69.23  ? 304 LEU G CG   1 
ATOM   9728  C  CD1  . LEU G 1 97  ? 8.837   -41.513 20.675  1.00 71.72  ? 304 LEU G CD1  1 
ATOM   9729  C  CD2  . LEU G 1 97  ? 7.752   -40.673 18.557  1.00 70.99  ? 304 LEU G CD2  1 
ATOM   9730  N  N    . ASP G 1 98  ? 5.290   -37.079 21.471  1.00 69.29  ? 305 ASP G N    1 
ATOM   9731  C  CA   . ASP G 1 98  ? 4.038   -36.712 22.115  1.00 64.94  ? 305 ASP G CA   1 
ATOM   9732  C  C    . ASP G 1 98  ? 3.163   -35.910 21.166  1.00 68.01  ? 305 ASP G C    1 
ATOM   9733  O  O    . ASP G 1 98  ? 1.942   -36.095 21.120  1.00 70.57  ? 305 ASP G O    1 
ATOM   9734  C  CB   . ASP G 1 98  ? 4.321   -35.927 23.396  1.00 65.16  ? 305 ASP G CB   1 
ATOM   9735  C  CG   . ASP G 1 98  ? 3.055   -35.438 24.072  1.00 66.60  ? 305 ASP G CG   1 
ATOM   9736  O  OD1  . ASP G 1 98  ? 2.568   -34.355 23.693  1.00 69.99  ? 305 ASP G OD1  1 
ATOM   9737  O  OD2  . ASP G 1 98  ? 2.536   -36.139 24.976  1.00 76.30  ? 305 ASP G OD2  1 
ATOM   9738  N  N    . ASN G 1 99  ? 3.782   -35.051 20.368  1.00 71.81  ? 306 ASN G N    1 
ATOM   9739  C  CA   . ASN G 1 99  ? 3.017   -34.206 19.417  1.00 76.47  ? 306 ASN G CA   1 
ATOM   9740  C  C    . ASN G 1 99  ? 2.383   -35.077 18.333  1.00 72.77  ? 306 ASN G C    1 
ATOM   9741  O  O    . ASN G 1 99  ? 1.206   -34.870 18.055  1.00 58.87  ? 306 ASN G O    1 
ATOM   9742  C  CB   . ASN G 1 99  ? 3.904   -33.140 18.777  1.00 72.72  ? 306 ASN G CB   1 
ATOM   9743  C  CG   . ASN G 1 99  ? 3.127   -31.932 18.304  1.00 84.65  ? 306 ASN G CG   1 
ATOM   9744  O  OD1  . ASN G 1 99  ? 2.129   -31.551 18.911  1.00 83.88  ? 306 ASN G OD1  1 
ATOM   9745  N  ND2  . ASN G 1 99  ? 3.576   -31.327 17.218  1.00 83.30  ? 306 ASN G ND2  1 
ATOM   9746  N  N    . VAL G 1 100 ? 3.154   -35.990 17.743  1.00 72.78  ? 307 VAL G N    1 
ATOM   9747  C  CA   . VAL G 1 100 ? 2.659   -36.829 16.655  1.00 72.47  ? 307 VAL G CA   1 
ATOM   9748  C  C    . VAL G 1 100 ? 1.624   -37.831 17.162  1.00 74.58  ? 307 VAL G C    1 
ATOM   9749  O  O    . VAL G 1 100 ? 0.626   -38.101 16.484  1.00 72.95  ? 307 VAL G O    1 
ATOM   9750  C  CB   . VAL G 1 100 ? 3.837   -37.529 15.955  1.00 74.36  ? 307 VAL G CB   1 
ATOM   9751  C  CG1  . VAL G 1 100 ? 3.329   -38.500 14.884  1.00 75.61  ? 307 VAL G CG1  1 
ATOM   9752  C  CG2  . VAL G 1 100 ? 4.775   -36.497 15.354  1.00 69.00  ? 307 VAL G CG2  1 
ATOM   9753  N  N    . GLU G 1 101 ? 1.839   -38.391 18.362  1.00 75.30  ? 308 GLU G N    1 
ATOM   9754  C  CA   . GLU G 1 101 ? 0.847   -39.285 18.960  1.00 77.23  ? 308 GLU G CA   1 
ATOM   9755  C  C    . GLU G 1 101 ? -0.500  -38.585 19.135  1.00 76.36  ? 308 GLU G C    1 
ATOM   9756  O  O    . GLU G 1 101 ? -1.543  -39.133 18.771  1.00 79.07  ? 308 GLU G O    1 
ATOM   9757  C  CB   . GLU G 1 101 ? 1.339   -39.828 20.306  1.00 75.08  ? 308 GLU G CB   1 
ATOM   9758  C  CG   . GLU G 1 101 ? 0.261   -40.624 21.046  1.00 75.81  ? 308 GLU G CG   1 
ATOM   9759  C  CD   . GLU G 1 101 ? 0.650   -41.064 22.462  1.00 77.12  ? 308 GLU G CD   1 
ATOM   9760  O  OE1  . GLU G 1 101 ? -0.256  -41.074 23.333  1.00 77.84  ? 308 GLU G OE1  1 
ATOM   9761  O  OE2  . GLU G 1 101 ? 1.834   -41.417 22.699  1.00 63.93  ? 308 GLU G OE2  1 
ATOM   9762  N  N    . ASN G 1 102 ? -0.507  -37.378 19.700  1.00 76.84  ? 309 ASN G N    1 
ATOM   9763  C  CA   . ASN G 1 102 ? -1.770  -36.654 19.731  1.00 77.98  ? 309 ASN G CA   1 
ATOM   9764  C  C    . ASN G 1 102 ? -2.142  -36.112 18.353  1.00 80.36  ? 309 ASN G C    1 
ATOM   9765  O  O    . ASN G 1 102 ? -3.321  -35.829 18.101  1.00 83.69  ? 309 ASN G O    1 
ATOM   9766  C  CB   . ASN G 1 102 ? -1.740  -35.519 20.759  1.00 73.78  ? 309 ASN G CB   1 
ATOM   9767  C  CG   . ASN G 1 102 ? -3.109  -34.821 20.889  1.00 90.01  ? 309 ASN G CG   1 
ATOM   9768  O  OD1  . ASN G 1 102 ? -4.124  -35.473 21.155  1.00 91.16  ? 309 ASN G OD1  1 
ATOM   9769  N  ND2  . ASN G 1 102 ? -3.140  -33.501 20.673  1.00 83.27  ? 309 ASN G ND2  1 
ATOM   9770  N  N    . LYS G 1 103 ? -1.171  -35.966 17.453  1.00 74.18  ? 310 LYS G N    1 
ATOM   9771  C  CA   . LYS G 1 103 ? -1.515  -35.609 16.084  1.00 75.15  ? 310 LYS G CA   1 
ATOM   9772  C  C    . LYS G 1 103 ? -2.340  -36.716 15.448  1.00 80.75  ? 310 LYS G C    1 
ATOM   9773  O  O    . LYS G 1 103 ? -3.285  -36.447 14.696  1.00 84.03  ? 310 LYS G O    1 
ATOM   9774  N  N    . MET G 1 104 ? -2.013  -37.969 15.762  1.00 78.16  ? 311 MET G N    1 
ATOM   9775  C  CA   . MET G 1 104 ? -2.768  -39.121 15.294  1.00 73.97  ? 311 MET G CA   1 
ATOM   9776  C  C    . MET G 1 104 ? -4.040  -39.363 16.092  1.00 76.70  ? 311 MET G C    1 
ATOM   9777  O  O    . MET G 1 104 ? -4.717  -40.364 15.844  1.00 76.84  ? 311 MET G O    1 
ATOM   9778  C  CB   . MET G 1 104 ? -1.894  -40.371 15.341  1.00 69.51  ? 311 MET G CB   1 
ATOM   9779  C  CG   . MET G 1 104 ? -0.654  -40.239 14.521  1.00 70.65  ? 311 MET G CG   1 
ATOM   9780  S  SD   . MET G 1 104 ? 0.405   -41.665 14.700  1.00 80.27  ? 311 MET G SD   1 
ATOM   9781  C  CE   . MET G 1 104 ? 1.558   -41.401 13.345  1.00 79.26  ? 311 MET G CE   1 
ATOM   9782  N  N    . LYS G 1 105 ? -4.374  -38.494 17.044  1.00 75.76  ? 312 LYS G N    1 
ATOM   9783  C  CA   . LYS G 1 105 ? -5.581  -38.693 17.834  1.00 80.77  ? 312 LYS G CA   1 
ATOM   9784  C  C    . LYS G 1 105 ? -6.793  -38.645 16.918  1.00 79.13  ? 312 LYS G C    1 
ATOM   9785  O  O    . LYS G 1 105 ? -6.945  -37.712 16.123  1.00 81.76  ? 312 LYS G O    1 
ATOM   9786  N  N    . GLY G 1 106 ? -7.637  -39.670 17.006  1.00 70.50  ? 313 GLY G N    1 
ATOM   9787  C  CA   . GLY G 1 106 ? -8.855  -39.693 16.219  1.00 72.90  ? 313 GLY G CA   1 
ATOM   9788  C  C    . GLY G 1 106 ? -8.659  -39.955 14.745  1.00 75.34  ? 313 GLY G C    1 
ATOM   9789  O  O    . GLY G 1 106 ? -9.429  -39.440 13.930  1.00 72.73  ? 313 GLY G O    1 
ATOM   9790  N  N    . THR G 1 107 ? -7.619  -40.729 14.428  1.00 79.79  ? 314 THR G N    1 
ATOM   9791  C  CA   . THR G 1 107 ? -7.290  -41.060 13.021  1.00 86.31  ? 314 THR G CA   1 
ATOM   9792  C  C    . THR G 1 107 ? -7.149  -42.570 12.828  1.00 84.73  ? 314 THR G C    1 
ATOM   9793  O  O    . THR G 1 107 ? -7.303  -43.319 13.808  1.00 81.22  ? 314 THR G O    1 
ATOM   9794  C  CB   . THR G 1 107 ? -5.968  -40.419 12.576  1.00 87.49  ? 314 THR G CB   1 
ATOM   9795  O  OG1  . THR G 1 107 ? -4.875  -41.137 13.153  1.00 83.38  ? 314 THR G OG1  1 
ATOM   9796  C  CG2  . THR G 1 107 ? -5.862  -38.954 12.937  1.00 82.18  ? 314 THR G CG2  1 
ATOM   9797  N  N    . CYS G 1 108 ? -6.837  -42.983 11.601  1.00 88.72  ? 315 CYS G N    1 
ATOM   9798  C  CA   . CYS G 1 108 ? -6.658  -44.423 11.283  1.00 91.09  ? 315 CYS G CA   1 
ATOM   9799  C  C    . CYS G 1 108 ? -5.450  -45.001 12.014  1.00 89.33  ? 315 CYS G C    1 
ATOM   9800  O  O    . CYS G 1 108 ? -5.398  -46.232 12.165  1.00 88.28  ? 315 CYS G O    1 
ATOM   9801  C  CB   . CYS G 1 108 ? -6.414  -44.595 9.791   1.00 87.75  ? 315 CYS G CB   1 
ATOM   9802  N  N    . VAL G 1 109 ? -4.503  -44.155 12.418  1.00 83.34  ? 316 VAL G N    1 
ATOM   9803  C  CA   . VAL G 1 109 ? -3.298  -44.679 13.055  1.00 85.28  ? 316 VAL G CA   1 
ATOM   9804  C  C    . VAL G 1 109 ? -3.229  -44.300 14.535  1.00 79.23  ? 316 VAL G C    1 
ATOM   9805  O  O    . VAL G 1 109 ? -2.164  -44.346 15.137  1.00 73.75  ? 316 VAL G O    1 
ATOM   9806  C  CB   . VAL G 1 109 ? -2.023  -44.240 12.308  1.00 81.19  ? 316 VAL G CB   1 
ATOM   9807  C  CG1  . VAL G 1 109 ? -1.790  -45.141 11.112  1.00 81.93  ? 316 VAL G CG1  1 
ATOM   9808  C  CG2  . VAL G 1 109 ? -2.117  -42.791 11.882  1.00 81.44  ? 316 VAL G CG2  1 
ATOM   9809  N  N    . GLU G 1 110 ? -4.360  -43.922 15.123  1.00 76.02  ? 317 GLU G N    1 
ATOM   9810  C  CA   . GLU G 1 110 ? -4.398  -43.660 16.551  1.00 74.60  ? 317 GLU G CA   1 
ATOM   9811  C  C    . GLU G 1 110 ? -3.862  -44.857 17.326  1.00 69.22  ? 317 GLU G C    1 
ATOM   9812  O  O    . GLU G 1 110 ? -4.137  -46.011 16.990  1.00 74.48  ? 317 GLU G O    1 
ATOM   9813  C  CB   . GLU G 1 110 ? -5.823  -43.338 16.984  1.00 72.65  ? 317 GLU G CB   1 
ATOM   9814  C  CG   . GLU G 1 110 ? -5.956  -42.922 18.420  1.00 74.38  ? 317 GLU G CG   1 
ATOM   9815  C  CD   . GLU G 1 110 ? -7.313  -42.320 18.711  1.00 81.72  ? 317 GLU G CD   1 
ATOM   9816  O  OE1  . GLU G 1 110 ? -7.511  -41.802 19.830  1.00 79.25  ? 317 GLU G OE1  1 
ATOM   9817  O  OE2  . GLU G 1 110 ? -8.186  -42.364 17.815  1.00 87.15  ? 317 GLU G OE2  1 
ATOM   9818  N  N    . GLY G 1 111 ? -2.985  -44.587 18.287  1.00 68.00  ? 318 GLY G N    1 
ATOM   9819  C  CA   . GLY G 1 111 ? -2.429  -45.660 19.125  1.00 67.85  ? 318 GLY G CA   1 
ATOM   9820  C  C    . GLY G 1 111 ? -1.133  -46.243 18.602  1.00 71.00  ? 318 GLY G C    1 
ATOM   9821  O  O    . GLY G 1 111 ? -0.635  -47.160 19.249  1.00 69.79  ? 318 GLY G O    1 
ATOM   9822  N  N    . THR G 1 112 ? -0.595  -45.726 17.499  1.00 67.29  ? 319 THR G N    1 
ATOM   9823  C  CA   . THR G 1 112 ? 0.616   -46.340 16.899  1.00 67.30  ? 319 THR G CA   1 
ATOM   9824  C  C    . THR G 1 112 ? 1.830   -46.111 17.802  1.00 72.65  ? 319 THR G C    1 
ATOM   9825  O  O    . THR G 1 112 ? 2.425   -47.106 18.223  1.00 70.63  ? 319 THR G O    1 
ATOM   9826  C  CB   . THR G 1 112 ? 0.863   -45.819 15.483  1.00 71.18  ? 319 THR G CB   1 
ATOM   9827  O  OG1  . THR G 1 112 ? -0.210  -46.257 14.653  1.00 72.64  ? 319 THR G OG1  1 
ATOM   9828  C  CG2  . THR G 1 112 ? 2.175   -46.310 14.912  1.00 75.60  ? 319 THR G CG2  1 
ATOM   9829  N  N    . ILE G 1 113 ? 2.174   -44.851 18.079  1.00 71.29  ? 320 ILE G N    1 
ATOM   9830  C  CA   . ILE G 1 113 ? 3.313   -44.528 18.991  1.00 72.81  ? 320 ILE G CA   1 
ATOM   9831  C  C    . ILE G 1 113 ? 3.137   -45.280 20.316  1.00 70.75  ? 320 ILE G C    1 
ATOM   9832  O  O    . ILE G 1 113 ? 4.084   -45.952 20.700  1.00 69.26  ? 320 ILE G O    1 
ATOM   9833  C  CB   . ILE G 1 113 ? 3.514   -43.002 19.149  1.00 73.17  ? 320 ILE G CB   1 
ATOM   9834  C  CG1  . ILE G 1 113 ? 4.208   -42.407 17.926  1.00 74.20  ? 320 ILE G CG1  1 
ATOM   9835  C  CG2  . ILE G 1 113 ? 4.266   -42.649 20.422  1.00 70.15  ? 320 ILE G CG2  1 
ATOM   9836  C  CD1  . ILE G 1 113 ? 3.326   -41.513 17.108  1.00 80.90  ? 320 ILE G CD1  1 
ATOM   9837  N  N    . PRO G 1 114 ? 1.997   -45.235 21.038  1.00 68.03  ? 321 PRO G N    1 
ATOM   9838  C  CA   . PRO G 1 114 ? 1.851   -46.052 22.233  1.00 65.49  ? 321 PRO G CA   1 
ATOM   9839  C  C    . PRO G 1 114 ? 2.126   -47.538 21.966  1.00 71.99  ? 321 PRO G C    1 
ATOM   9840  O  O    . PRO G 1 114 ? 2.912   -48.109 22.661  1.00 70.63  ? 321 PRO G O    1 
ATOM   9841  C  CB   . PRO G 1 114 ? 0.381   -45.885 22.595  1.00 57.17  ? 321 PRO G CB   1 
ATOM   9842  C  CG   . PRO G 1 114 ? 0.031   -44.515 22.112  1.00 60.91  ? 321 PRO G CG   1 
ATOM   9843  C  CD   . PRO G 1 114 ? 0.835   -44.359 20.844  1.00 68.38  ? 321 PRO G CD   1 
ATOM   9844  N  N    . LYS G 1 115 ? 1.495   -48.132 20.953  1.00 76.57  ? 322 LYS G N    1 
ATOM   9845  C  CA   . LYS G 1 115 ? 1.639   -49.597 20.725  1.00 65.28  ? 322 LYS G CA   1 
ATOM   9846  C  C    . LYS G 1 115 ? 3.088   -49.951 20.412  1.00 71.38  ? 322 LYS G C    1 
ATOM   9847  O  O    . LYS G 1 115 ? 3.452   -51.096 20.662  1.00 77.71  ? 322 LYS G O    1 
ATOM   9848  C  CB   . LYS G 1 115 ? 0.737   -50.070 19.585  1.00 62.93  ? 322 LYS G CB   1 
ATOM   9849  N  N    . LEU G 1 116 ? 3.862   -49.005 19.886  1.00 70.42  ? 323 LEU G N    1 
ATOM   9850  C  CA   . LEU G 1 116 ? 5.263   -49.276 19.496  1.00 67.13  ? 323 LEU G CA   1 
ATOM   9851  C  C    . LEU G 1 116 ? 6.228   -48.838 20.591  1.00 68.42  ? 323 LEU G C    1 
ATOM   9852  O  O    . LEU G 1 116 ? 7.286   -49.463 20.698  1.00 65.81  ? 323 LEU G O    1 
ATOM   9853  C  CB   . LEU G 1 116 ? 5.560   -48.504 18.210  1.00 75.31  ? 323 LEU G CB   1 
ATOM   9854  C  CG   . LEU G 1 116 ? 4.908   -49.036 16.938  1.00 74.73  ? 323 LEU G CG   1 
ATOM   9855  C  CD1  . LEU G 1 116 ? 5.455   -48.313 15.722  1.00 77.01  ? 323 LEU G CD1  1 
ATOM   9856  C  CD2  . LEU G 1 116 ? 5.120   -50.533 16.805  1.00 74.97  ? 323 LEU G CD2  1 
ATOM   9857  N  N    . PHE G 1 117 ? 5.880   -47.822 21.380  1.00 65.39  ? 324 PHE G N    1 
ATOM   9858  C  CA   . PHE G 1 117 ? 6.864   -47.305 22.324  1.00 64.18  ? 324 PHE G CA   1 
ATOM   9859  C  C    . PHE G 1 117 ? 6.476   -47.399 23.792  1.00 65.33  ? 324 PHE G C    1 
ATOM   9860  O  O    . PHE G 1 117 ? 7.370   -47.308 24.640  1.00 63.75  ? 324 PHE G O    1 
ATOM   9861  C  CB   . PHE G 1 117 ? 7.185   -45.836 22.005  1.00 65.43  ? 324 PHE G CB   1 
ATOM   9862  C  CG   . PHE G 1 117 ? 7.738   -45.623 20.619  1.00 68.80  ? 324 PHE G CG   1 
ATOM   9863  C  CD1  . PHE G 1 117 ? 9.071   -45.909 20.335  1.00 64.12  ? 324 PHE G CD1  1 
ATOM   9864  C  CD2  . PHE G 1 117 ? 6.928   -45.147 19.603  1.00 66.69  ? 324 PHE G CD2  1 
ATOM   9865  C  CE1  . PHE G 1 117 ? 9.585   -45.712 19.071  1.00 62.22  ? 324 PHE G CE1  1 
ATOM   9866  C  CE2  . PHE G 1 117 ? 7.437   -44.947 18.337  1.00 67.95  ? 324 PHE G CE2  1 
ATOM   9867  C  CZ   . PHE G 1 117 ? 8.765   -45.231 18.069  1.00 65.85  ? 324 PHE G CZ   1 
ATOM   9868  N  N    . ARG G 1 118 ? 5.190   -47.586 24.123  1.00 70.60  ? 325 ARG G N    1 
ATOM   9869  C  CA   . ARG G 1 118 ? 4.712   -47.518 25.509  1.00 67.26  ? 325 ARG G CA   1 
ATOM   9870  C  C    . ARG G 1 118 ? 4.829   -48.867 26.206  1.00 60.38  ? 325 ARG G C    1 
ATOM   9871  O  O    . ARG G 1 118 ? 4.315   -49.871 25.710  1.00 68.43  ? 325 ARG G O    1 
ATOM   9872  C  CB   . ARG G 1 118 ? 3.259   -47.033 25.571  1.00 61.27  ? 325 ARG G CB   1 
ATOM   9873  C  CG   . ARG G 1 118 ? 2.683   -46.940 26.969  1.00 55.03  ? 325 ARG G CG   1 
ATOM   9874  N  N    . GLY G 1 119 ? 5.505   -48.879 27.355  1.00 57.89  ? 326 GLY G N    1 
ATOM   9875  C  CA   . GLY G 1 119 ? 5.524   -50.013 28.248  1.00 60.22  ? 326 GLY G CA   1 
ATOM   9876  C  C    . GLY G 1 119 ? 4.880   -49.674 29.579  1.00 57.56  ? 326 GLY G C    1 
ATOM   9877  O  O    . GLY G 1 119 ? 4.325   -48.587 29.759  1.00 57.65  ? 326 GLY G O    1 
ATOM   9878  N  N    . LYS G 1 120 ? 4.973   -50.629 30.527  1.00 51.91  ? 327 LYS G N    1 
ATOM   9879  C  CA   . LYS G 1 120 ? 4.345   -50.469 31.843  1.00 53.51  ? 327 LYS G CA   1 
ATOM   9880  C  C    . LYS G 1 120 ? 5.219   -51.019 32.959  1.00 51.34  ? 327 LYS G C    1 
ATOM   9881  O  O    . LYS G 1 120 ? 5.709   -52.142 32.858  1.00 57.91  ? 327 LYS G O    1 
ATOM   9882  C  CB   . LYS G 1 120 ? 2.986   -51.182 31.903  1.00 57.22  ? 327 LYS G CB   1 
ATOM   9883  C  CG   . LYS G 1 120 ? 2.262   -51.020 33.247  1.00 59.18  ? 327 LYS G CG   1 
ATOM   9884  C  CD   . LYS G 1 120 ? 1.201   -49.898 33.174  1.00 57.14  ? 327 LYS G CD   1 
ATOM   9885  N  N    . MET G 1 121 ? 5.349   -50.250 34.038  1.00 55.99  ? 328 MET G N    1 
ATOM   9886  C  CA   . MET G 1 121 ? 6.190   -50.664 35.189  1.00 54.87  ? 328 MET G CA   1 
ATOM   9887  C  C    . MET G 1 121 ? 5.360   -50.796 36.468  1.00 51.45  ? 328 MET G C    1 
ATOM   9888  O  O    . MET G 1 121 ? 4.229   -50.328 36.484  1.00 51.70  ? 328 MET G O    1 
ATOM   9889  C  CB   . MET G 1 121 ? 7.315   -49.653 35.425  1.00 54.92  ? 328 MET G CB   1 
ATOM   9890  C  CG   . MET G 1 121 ? 6.835   -48.269 35.817  1.00 58.09  ? 328 MET G CG   1 
ATOM   9891  S  SD   . MET G 1 121 ? 8.165   -47.074 36.080  1.00 63.40  ? 328 MET G SD   1 
ATOM   9892  C  CE   . MET G 1 121 ? 9.177   -47.375 34.635  1.00 52.26  ? 328 MET G CE   1 
ATOM   9893  N  N    . VAL G 1 122 ? 5.930   -51.404 37.489  1.00 57.11  ? 329 VAL G N    1 
ATOM   9894  C  CA   . VAL G 1 122 ? 5.207   -51.541 38.775  1.00 56.53  ? 329 VAL G CA   1 
ATOM   9895  C  C    . VAL G 1 122 ? 6.170   -51.183 39.910  1.00 53.86  ? 329 VAL G C    1 
ATOM   9896  O  O    . VAL G 1 122 ? 7.299   -51.665 39.894  1.00 55.57  ? 329 VAL G O    1 
ATOM   9897  C  CB   . VAL G 1 122 ? 4.576   -52.941 38.897  1.00 59.70  ? 329 VAL G CB   1 
ATOM   9898  C  CG1  . VAL G 1 122 ? 5.543   -54.082 38.641  1.00 61.96  ? 329 VAL G CG1  1 
ATOM   9899  C  CG2  . VAL G 1 122 ? 3.800   -53.124 40.180  1.00 55.05  ? 329 VAL G CG2  1 
ATOM   9900  N  N    . SER G 1 123 ? 5.730   -50.329 40.831  1.00 51.68  ? 330 SER G N    1 
ATOM   9901  C  CA   . SER G 1 123 ? 6.585   -49.919 41.966  1.00 49.79  ? 330 SER G CA   1 
ATOM   9902  C  C    . SER G 1 123 ? 6.001   -50.546 43.231  1.00 54.38  ? 330 SER G C    1 
ATOM   9903  O  O    . SER G 1 123 ? 4.814   -50.341 43.487  1.00 55.06  ? 330 SER G O    1 
ATOM   9904  C  CB   . SER G 1 123 ? 6.677   -48.428 42.068  1.00 47.06  ? 330 SER G CB   1 
ATOM   9905  O  OG   . SER G 1 123 ? 6.993   -47.841 40.816  1.00 55.37  ? 330 SER G OG   1 
ATOM   9906  N  N    . TYR G 1 124 ? 6.806   -51.303 43.975  1.00 54.02  ? 331 TYR G N    1 
ATOM   9907  C  CA   . TYR G 1 124 ? 6.273   -51.993 45.164  1.00 57.66  ? 331 TYR G CA   1 
ATOM   9908  C  C    . TYR G 1 124 ? 6.826   -51.321 46.408  1.00 62.66  ? 331 TYR G C    1 
ATOM   9909  O  O    . TYR G 1 124 ? 8.033   -51.213 46.516  1.00 62.55  ? 331 TYR G O    1 
ATOM   9910  C  CB   . TYR G 1 124 ? 6.644   -53.475 45.153  1.00 56.94  ? 331 TYR G CB   1 
ATOM   9911  C  CG   . TYR G 1 124 ? 6.062   -54.294 44.031  1.00 57.80  ? 331 TYR G CG   1 
ATOM   9912  C  CD1  . TYR G 1 124 ? 4.786   -54.819 44.120  1.00 57.54  ? 331 TYR G CD1  1 
ATOM   9913  C  CD2  . TYR G 1 124 ? 6.800   -54.573 42.893  1.00 62.50  ? 331 TYR G CD2  1 
ATOM   9914  C  CE1  . TYR G 1 124 ? 4.247   -55.583 43.100  1.00 49.21  ? 331 TYR G CE1  1 
ATOM   9915  C  CE2  . TYR G 1 124 ? 6.278   -55.338 41.865  1.00 65.58  ? 331 TYR G CE2  1 
ATOM   9916  C  CZ   . TYR G 1 124 ? 4.996   -55.845 41.970  1.00 61.00  ? 331 TYR G CZ   1 
ATOM   9917  O  OH   . TYR G 1 124 ? 4.467   -56.591 40.959  1.00 64.47  ? 331 TYR G OH   1 
ATOM   9918  N  N    . ILE G 1 125 ? 5.953   -50.882 47.299  1.00 65.06  ? 332 ILE G N    1 
ATOM   9919  C  CA   . ILE G 1 125 ? 6.321   -50.269 48.569  1.00 56.14  ? 332 ILE G CA   1 
ATOM   9920  C  C    . ILE G 1 125 ? 5.944   -51.220 49.690  1.00 56.45  ? 332 ILE G C    1 
ATOM   9921  O  O    . ILE G 1 125 ? 4.776   -51.610 49.811  1.00 64.07  ? 332 ILE G O    1 
ATOM   9922  C  CB   . ILE G 1 125 ? 5.604   -48.930 48.781  1.00 57.09  ? 332 ILE G CB   1 
ATOM   9923  C  CG1  . ILE G 1 125 ? 5.709   -48.057 47.541  1.00 57.50  ? 332 ILE G CG1  1 
ATOM   9924  C  CG2  . ILE G 1 125 ? 6.139   -48.269 50.036  1.00 62.13  ? 332 ILE G CG2  1 
ATOM   9925  C  CD1  . ILE G 1 125 ? 7.092   -47.586 47.282  1.00 61.40  ? 332 ILE G CD1  1 
ATOM   9926  N  N    . GLN G 1 126 ? 6.904   -51.532 50.550  1.00 60.69  ? 333 GLN G N    1 
ATOM   9927  C  CA   . GLN G 1 126 ? 6.702   -52.481 51.642  1.00 65.87  ? 333 GLN G CA   1 
ATOM   9928  C  C    . GLN G 1 126 ? 7.237   -51.877 52.937  1.00 62.01  ? 333 GLN G C    1 
ATOM   9929  O  O    . GLN G 1 126 ? 8.457   -51.763 53.108  1.00 62.79  ? 333 GLN G O    1 
ATOM   9930  C  CB   . GLN G 1 126 ? 7.397   -53.814 51.333  1.00 59.25  ? 333 GLN G CB   1 
ATOM   9931  C  CG   . GLN G 1 126 ? 7.393   -54.787 52.486  1.00 58.69  ? 333 GLN G CG   1 
ATOM   9932  C  CD   . GLN G 1 126 ? 6.006   -55.259 52.787  1.00 66.22  ? 333 GLN G CD   1 
ATOM   9933  O  OE1  . GLN G 1 126 ? 5.457   -56.083 52.052  1.00 72.37  ? 333 GLN G OE1  1 
ATOM   9934  N  NE2  . GLN G 1 126 ? 5.405   -54.722 53.856  1.00 62.29  ? 333 GLN G NE2  1 
ATOM   9935  N  N    . CYS G 1 127 ? 6.340   -51.504 53.855  1.00 59.61  ? 334 CYS G N    1 
ATOM   9936  C  CA   . CYS G 1 127 ? 6.782   -50.983 55.149  1.00 63.89  ? 334 CYS G CA   1 
ATOM   9937  C  C    . CYS G 1 127 ? 7.643   -52.009 55.895  1.00 67.49  ? 334 CYS G C    1 
ATOM   9938  O  O    . CYS G 1 127 ? 7.435   -53.221 55.798  1.00 69.02  ? 334 CYS G O    1 
ATOM   9939  C  CB   . CYS G 1 127 ? 5.586   -50.590 56.008  1.00 61.80  ? 334 CYS G CB   1 
ATOM   9940  S  SG   . CYS G 1 127 ? 4.701   -49.094 55.479  1.00 66.35  ? 334 CYS G SG   1 
ATOM   9941  N  N    . LYS G 1 128 ? 8.620   -51.514 56.659  1.00 67.32  ? 335 LYS G N    1 
ATOM   9942  C  CA   . LYS G 1 128 ? 9.534   -52.389 57.388  1.00 69.92  ? 335 LYS G CA   1 
ATOM   9943  C  C    . LYS G 1 128 ? 9.156   -52.609 58.853  1.00 75.34  ? 335 LYS G C    1 
ATOM   9944  O  O    . LYS G 1 128 ? 9.552   -53.631 59.429  1.00 78.39  ? 335 LYS G O    1 
ATOM   9945  C  CB   . LYS G 1 128 ? 10.967  -51.839 57.322  1.00 59.91  ? 335 LYS G CB   1 
ATOM   9946  N  N    . GLU G 1 129 ? 8.404   -51.689 59.469  1.00 72.13  ? 336 GLU G N    1 
ATOM   9947  C  CA   . GLU G 1 129 ? 8.139   -51.723 60.902  1.00 68.53  ? 336 GLU G CA   1 
ATOM   9948  C  C    . GLU G 1 129 ? 6.674   -51.909 61.263  1.00 74.10  ? 336 GLU G C    1 
ATOM   9949  O  O    . GLU G 1 129 ? 6.382   -52.238 62.419  1.00 83.81  ? 336 GLU G O    1 
ATOM   9950  N  N    . VAL G 1 130 ? 5.792   -51.703 60.286  1.00 73.89  ? 337 VAL G N    1 
ATOM   9951  C  CA   . VAL G 1 130 ? 4.340   -51.979 60.460  1.00 70.07  ? 337 VAL G CA   1 
ATOM   9952  C  C    . VAL G 1 130 ? 3.930   -52.864 59.275  1.00 72.85  ? 337 VAL G C    1 
ATOM   9953  O  O    . VAL G 1 130 ? 4.771   -53.107 58.393  1.00 76.10  ? 337 VAL G O    1 
ATOM   9954  C  CB   . VAL G 1 130 ? 3.507   -50.686 60.519  1.00 72.56  ? 337 VAL G CB   1 
ATOM   9955  C  CG1  . VAL G 1 130 ? 3.838   -49.826 61.726  1.00 65.44  ? 337 VAL G CG1  1 
ATOM   9956  C  CG2  . VAL G 1 130 ? 3.602   -49.879 59.237  1.00 72.55  ? 337 VAL G CG2  1 
ATOM   9957  N  N    . ASP G 1 131 ? 2.693   -53.351 59.258  1.00 74.63  ? 338 ASP G N    1 
ATOM   9958  C  CA   . ASP G 1 131 ? 2.198   -54.173 58.121  1.00 73.28  ? 338 ASP G CA   1 
ATOM   9959  C  C    . ASP G 1 131 ? 1.407   -53.290 57.160  1.00 77.68  ? 338 ASP G C    1 
ATOM   9960  O  O    . ASP G 1 131 ? 0.243   -52.995 57.465  1.00 77.86  ? 338 ASP G O    1 
ATOM   9961  C  CB   . ASP G 1 131 ? 1.383   -55.376 58.592  1.00 79.88  ? 338 ASP G CB   1 
ATOM   9962  C  CG   . ASP G 1 131 ? 1.212   -56.438 57.521  1.00 87.89  ? 338 ASP G CG   1 
ATOM   9963  O  OD1  . ASP G 1 131 ? 2.082   -56.523 56.629  1.00 88.53  ? 338 ASP G OD1  1 
ATOM   9964  O  OD2  . ASP G 1 131 ? 0.209   -57.171 57.586  1.00 84.65  ? 338 ASP G OD2  1 
ATOM   9965  N  N    . TYR G 1 132 ? 2.028   -52.899 56.048  1.00 74.38  ? 339 TYR G N    1 
ATOM   9966  C  CA   . TYR G 1 132 ? 1.383   -52.031 55.036  1.00 66.67  ? 339 TYR G CA   1 
ATOM   9967  C  C    . TYR G 1 132 ? 2.158   -52.193 53.735  1.00 64.32  ? 339 TYR G C    1 
ATOM   9968  O  O    . TYR G 1 132 ? 3.391   -52.142 53.757  1.00 65.52  ? 339 TYR G O    1 
ATOM   9969  C  CB   . TYR G 1 132 ? 1.388   -50.580 55.507  1.00 63.68  ? 339 TYR G CB   1 
ATOM   9970  C  CG   . TYR G 1 132 ? 0.550   -49.587 54.745  1.00 66.78  ? 339 TYR G CG   1 
ATOM   9971  C  CD1  . TYR G 1 132 ? 1.024   -48.977 53.596  1.00 64.06  ? 339 TYR G CD1  1 
ATOM   9972  C  CD2  . TYR G 1 132 ? -0.691  -49.202 55.217  1.00 66.58  ? 339 TYR G CD2  1 
ATOM   9973  C  CE1  . TYR G 1 132 ? 0.265   -48.046 52.909  1.00 63.71  ? 339 TYR G CE1  1 
ATOM   9974  C  CE2  . TYR G 1 132 ? -1.462  -48.270 54.546  1.00 62.62  ? 339 TYR G CE2  1 
ATOM   9975  C  CZ   . TYR G 1 132 ? -0.981  -47.688 53.389  1.00 65.22  ? 339 TYR G CZ   1 
ATOM   9976  O  OH   . TYR G 1 132 ? -1.739  -46.770 52.725  1.00 64.38  ? 339 TYR G OH   1 
ATOM   9977  N  N    . ARG G 1 133 ? 1.442   -52.421 52.641  1.00 63.25  ? 340 ARG G N    1 
ATOM   9978  C  CA   . ARG G 1 133 ? 2.084   -52.498 51.312  1.00 64.37  ? 340 ARG G CA   1 
ATOM   9979  C  C    . ARG G 1 133 ? 1.309   -51.598 50.357  1.00 66.90  ? 340 ARG G C    1 
ATOM   9980  O  O    . ARG G 1 133 ? 0.098   -51.428 50.560  1.00 67.43  ? 340 ARG G O    1 
ATOM   9981  C  CB   . ARG G 1 133 ? 2.081   -53.917 50.741  1.00 65.74  ? 340 ARG G CB   1 
ATOM   9982  C  CG   . ARG G 1 133 ? 2.091   -55.040 51.766  1.00 74.29  ? 340 ARG G CG   1 
ATOM   9983  C  CD   . ARG G 1 133 ? 1.675   -56.341 51.114  1.00 83.11  ? 340 ARG G CD   1 
ATOM   9984  N  NE   . ARG G 1 133 ? 2.789   -57.269 51.013  1.00 76.54  ? 340 ARG G NE   1 
ATOM   9985  C  CZ   . ARG G 1 133 ? 2.977   -58.311 51.813  1.00 78.95  ? 340 ARG G CZ   1 
ATOM   9986  N  NH1  . ARG G 1 133 ? 2.119   -58.567 52.785  1.00 85.35  ? 340 ARG G NH1  1 
ATOM   9987  N  NH2  . ARG G 1 133 ? 4.027   -59.092 51.640  1.00 74.26  ? 340 ARG G NH2  1 
ATOM   9988  N  N    . SER G 1 134 ? 1.986   -51.032 49.364  1.00 61.58  ? 341 SER G N    1 
ATOM   9989  C  CA   . SER G 1 134 ? 1.257   -50.250 48.338  1.00 57.67  ? 341 SER G CA   1 
ATOM   9990  C  C    . SER G 1 134 ? 1.801   -50.573 46.952  1.00 54.32  ? 341 SER G C    1 
ATOM   9991  O  O    . SER G 1 134 ? 2.928   -51.072 46.856  1.00 56.55  ? 341 SER G O    1 
ATOM   9992  C  CB   . SER G 1 134 ? 1.279   -48.788 48.613  1.00 56.59  ? 341 SER G CB   1 
ATOM   9993  O  OG   . SER G 1 134 ? 0.100   -48.172 48.126  1.00 59.56  ? 341 SER G OG   1 
ATOM   9994  N  N    . ASP G 1 135 ? 1.016   -50.272 45.927  1.00 52.58  ? 342 ASP G N    1 
ATOM   9995  C  CA   . ASP G 1 135 ? 1.385   -50.658 44.550  1.00 54.55  ? 342 ASP G CA   1 
ATOM   9996  C  C    . ASP G 1 135 ? 1.023   -49.540 43.583  1.00 52.08  ? 342 ASP G C    1 
ATOM   9997  O  O    . ASP G 1 135 ? -0.053  -48.957 43.736  1.00 57.47  ? 342 ASP G O    1 
ATOM   9998  C  CB   . ASP G 1 135 ? 0.650   -51.942 44.168  1.00 59.15  ? 342 ASP G CB   1 
ATOM   9999  C  CG   . ASP G 1 135 ? 1.554   -53.028 43.638  1.00 62.97  ? 342 ASP G CG   1 
ATOM   10000 O  OD1  . ASP G 1 135 ? 2.588   -52.681 43.045  1.00 68.53  ? 342 ASP G OD1  1 
ATOM   10001 O  OD2  . ASP G 1 135 ? 1.202   -54.204 43.812  1.00 64.23  ? 342 ASP G OD2  1 
ATOM   10002 N  N    . ARG G 1 136 ? 1.887   -49.280 42.615  1.00 52.87  ? 343 ARG G N    1 
ATOM   10003 C  CA   . ARG G 1 136 ? 1.591   -48.275 41.565  1.00 54.14  ? 343 ARG G CA   1 
ATOM   10004 C  C    . ARG G 1 136 ? 2.087   -48.774 40.207  1.00 53.41  ? 343 ARG G C    1 
ATOM   10005 O  O    . ARG G 1 136 ? 3.249   -49.177 40.120  1.00 60.36  ? 343 ARG G O    1 
ATOM   10006 C  CB   . ARG G 1 136 ? 2.204   -46.924 41.941  1.00 56.13  ? 343 ARG G CB   1 
ATOM   10007 C  CG   . ARG G 1 136 ? 1.936   -45.804 40.949  1.00 57.25  ? 343 ARG G CG   1 
ATOM   10008 C  CD   . ARG G 1 136 ? 0.472   -45.630 40.600  1.00 64.57  ? 343 ARG G CD   1 
ATOM   10009 N  NE   . ARG G 1 136 ? -0.317  -45.351 41.786  1.00 66.28  ? 343 ARG G NE   1 
ATOM   10010 C  CZ   . ARG G 1 136 ? -0.558  -44.137 42.250  1.00 64.78  ? 343 ARG G CZ   1 
ATOM   10011 N  NH1  . ARG G 1 136 ? -0.074  -43.080 41.622  1.00 62.12  ? 343 ARG G NH1  1 
ATOM   10012 N  NH2  . ARG G 1 136 ? -1.282  -43.983 43.342  1.00 54.20  ? 343 ARG G NH2  1 
ATOM   10013 N  N    . ARG G 1 137 ? 1.230   -48.716 39.193  1.00 54.47  ? 344 ARG G N    1 
ATOM   10014 C  CA   . ARG G 1 137 ? 1.597   -49.147 37.824  1.00 50.60  ? 344 ARG G CA   1 
ATOM   10015 C  C    . ARG G 1 137 ? 1.576   -47.926 36.907  1.00 55.31  ? 344 ARG G C    1 
ATOM   10016 O  O    . ARG G 1 137 ? 0.536   -47.257 36.859  1.00 55.68  ? 344 ARG G O    1 
ATOM   10017 C  CB   . ARG G 1 137 ? 0.650   -50.256 37.369  1.00 47.92  ? 344 ARG G CB   1 
ATOM   10018 C  CG   . ARG G 1 137 ? 0.970   -51.616 37.965  1.00 54.81  ? 344 ARG G CG   1 
ATOM   10019 C  CD   . ARG G 1 137 ? -0.273  -52.444 38.200  1.00 47.66  ? 344 ARG G CD   1 
ATOM   10020 N  NE   . ARG G 1 137 ? 0.052   -53.604 39.011  1.00 56.90  ? 344 ARG G NE   1 
ATOM   10021 C  CZ   . ARG G 1 137 ? -0.081  -53.663 40.328  1.00 60.76  ? 344 ARG G CZ   1 
ATOM   10022 N  NH1  . ARG G 1 137 ? 0.250   -54.766 40.973  1.00 48.49  ? 344 ARG G NH1  1 
ATOM   10023 N  NH2  . ARG G 1 137 ? -0.550  -52.626 40.996  1.00 60.75  ? 344 ARG G NH2  1 
ATOM   10024 N  N    . GLU G 1 138 ? 2.681   -47.652 36.204  1.00 55.52  ? 345 GLU G N    1 
ATOM   10025 C  CA   . GLU G 1 138 ? 2.797   -46.444 35.395  1.00 56.41  ? 345 GLU G CA   1 
ATOM   10026 C  C    . GLU G 1 138 ? 3.342   -46.775 34.013  1.00 51.14  ? 345 GLU G C    1 
ATOM   10027 O  O    . GLU G 1 138 ? 4.228   -47.624 33.869  1.00 56.99  ? 345 GLU G O    1 
ATOM   10028 C  CB   . GLU G 1 138 ? 3.695   -45.406 36.109  1.00 55.31  ? 345 GLU G CB   1 
ATOM   10029 C  CG   . GLU G 1 138 ? 3.430   -45.387 37.617  1.00 59.01  ? 345 GLU G CG   1 
ATOM   10030 C  CD   . GLU G 1 138 ? 4.314   -44.454 38.439  1.00 61.84  ? 345 GLU G CD   1 
ATOM   10031 O  OE1  . GLU G 1 138 ? 3.887   -43.286 38.694  1.00 54.24  ? 345 GLU G OE1  1 
ATOM   10032 O  OE2  . GLU G 1 138 ? 5.400   -44.924 38.875  1.00 60.07  ? 345 GLU G OE2  1 
ATOM   10033 N  N    . ASP G 1 139 ? 2.785   -46.115 32.997  1.00 53.77  ? 346 ASP G N    1 
ATOM   10034 C  CA   . ASP G 1 139 ? 3.359   -46.130 31.659  1.00 54.47  ? 346 ASP G CA   1 
ATOM   10035 C  C    . ASP G 1 139 ? 4.728   -45.451 31.631  1.00 53.86  ? 346 ASP G C    1 
ATOM   10036 O  O    . ASP G 1 139 ? 5.073   -44.621 32.476  1.00 53.31  ? 346 ASP G O    1 
ATOM   10037 C  CB   . ASP G 1 139 ? 2.460   -45.422 30.642  1.00 54.26  ? 346 ASP G CB   1 
ATOM   10038 C  CG   . ASP G 1 139 ? 1.066   -46.029 30.551  1.00 58.03  ? 346 ASP G CG   1 
ATOM   10039 O  OD1  . ASP G 1 139 ? 0.910   -47.210 30.910  1.00 57.64  ? 346 ASP G OD1  1 
ATOM   10040 O  OD2  . ASP G 1 139 ? 0.129   -45.315 30.118  1.00 56.11  ? 346 ASP G OD2  1 
ATOM   10041 N  N    . TYR G 1 140 ? 5.510   -45.837 30.629  1.00 52.41  ? 347 TYR G N    1 
ATOM   10042 C  CA   . TYR G 1 140 ? 6.737   -45.167 30.262  1.00 51.94  ? 347 TYR G CA   1 
ATOM   10043 C  C    . TYR G 1 140 ? 6.867   -45.302 28.753  1.00 60.65  ? 347 TYR G C    1 
ATOM   10044 O  O    . TYR G 1 140 ? 6.273   -46.195 28.139  1.00 60.76  ? 347 TYR G O    1 
ATOM   10045 C  CB   . TYR G 1 140 ? 7.947   -45.763 30.995  1.00 51.11  ? 347 TYR G CB   1 
ATOM   10046 C  CG   . TYR G 1 140 ? 8.176   -47.223 30.682  1.00 58.73  ? 347 TYR G CG   1 
ATOM   10047 C  CD1  . TYR G 1 140 ? 7.545   -48.214 31.415  1.00 56.39  ? 347 TYR G CD1  1 
ATOM   10048 C  CD2  . TYR G 1 140 ? 9.019   -47.605 29.650  1.00 57.33  ? 347 TYR G CD2  1 
ATOM   10049 C  CE1  . TYR G 1 140 ? 7.757   -49.546 31.146  1.00 60.79  ? 347 TYR G CE1  1 
ATOM   10050 C  CE2  . TYR G 1 140 ? 9.234   -48.936 29.360  1.00 63.38  ? 347 TYR G CE2  1 
ATOM   10051 C  CZ   . TYR G 1 140 ? 8.594   -49.909 30.107  1.00 65.21  ? 347 TYR G CZ   1 
ATOM   10052 O  OH   . TYR G 1 140 ? 8.801   -51.241 29.826  1.00 57.74  ? 347 TYR G OH   1 
ATOM   10053 N  N    . TYR G 1 141 ? 7.609   -44.378 28.149  1.00 56.62  ? 348 TYR G N    1 
ATOM   10054 C  CA   . TYR G 1 141 ? 7.907   -44.466 26.734  1.00 51.91  ? 348 TYR G CA   1 
ATOM   10055 C  C    . TYR G 1 141 ? 9.402   -44.550 26.488  1.00 55.88  ? 348 TYR G C    1 
ATOM   10056 O  O    . TYR G 1 141 ? 9.817   -44.601 25.329  1.00 62.91  ? 348 TYR G O    1 
ATOM   10057 C  CB   . TYR G 1 141 ? 7.334   -43.267 25.974  1.00 56.04  ? 348 TYR G CB   1 
ATOM   10058 C  CG   . TYR G 1 141 ? 5.827   -43.208 25.745  1.00 54.02  ? 348 TYR G CG   1 
ATOM   10059 C  CD1  . TYR G 1 141 ? 4.921   -43.346 26.778  1.00 54.88  ? 348 TYR G CD1  1 
ATOM   10060 C  CD2  . TYR G 1 141 ? 5.329   -42.947 24.484  1.00 53.42  ? 348 TYR G CD2  1 
ATOM   10061 C  CE1  . TYR G 1 141 ? 3.563   -43.256 26.539  1.00 53.76  ? 348 TYR G CE1  1 
ATOM   10062 C  CE2  . TYR G 1 141 ? 4.006   -42.842 24.243  1.00 51.87  ? 348 TYR G CE2  1 
ATOM   10063 C  CZ   . TYR G 1 141 ? 3.116   -42.996 25.260  1.00 57.16  ? 348 TYR G CZ   1 
ATOM   10064 O  OH   . TYR G 1 141 ? 1.765   -42.883 24.968  1.00 61.49  ? 348 TYR G OH   1 
ATOM   10065 N  N    . ASP G 1 142 ? 10.213  -44.557 27.543  1.00 53.01  ? 349 ASP G N    1 
ATOM   10066 C  CA   . ASP G 1 142 ? 11.648  -44.801 27.461  1.00 52.71  ? 349 ASP G CA   1 
ATOM   10067 C  C    . ASP G 1 142 ? 12.130  -45.127 28.874  1.00 55.55  ? 349 ASP G C    1 
ATOM   10068 O  O    . ASP G 1 142 ? 11.356  -45.060 29.828  1.00 64.22  ? 349 ASP G O    1 
ATOM   10069 C  CB   . ASP G 1 142 ? 12.380  -43.612 26.820  1.00 62.30  ? 349 ASP G CB   1 
ATOM   10070 C  CG   . ASP G 1 142 ? 12.371  -42.332 27.686  1.00 63.64  ? 349 ASP G CG   1 
ATOM   10071 O  OD1  . ASP G 1 142 ? 11.787  -42.298 28.800  1.00 56.85  ? 349 ASP G OD1  1 
ATOM   10072 O  OD2  . ASP G 1 142 ? 12.984  -41.339 27.232  1.00 63.45  ? 349 ASP G OD2  1 
ATOM   10073 N  N    . ILE G 1 143 ? 13.402  -45.493 29.023  1.00 53.02  ? 350 ILE G N    1 
ATOM   10074 C  CA   . ILE G 1 143 ? 13.915  -45.885 30.334  1.00 55.02  ? 350 ILE G CA   1 
ATOM   10075 C  C    . ILE G 1 143 ? 15.211  -45.143 30.651  1.00 62.13  ? 350 ILE G C    1 
ATOM   10076 O  O    . ILE G 1 143 ? 16.118  -45.066 29.815  1.00 62.05  ? 350 ILE G O    1 
ATOM   10077 C  CB   . ILE G 1 143 ? 14.156  -47.401 30.425  1.00 53.96  ? 350 ILE G CB   1 
ATOM   10078 C  CG1  . ILE G 1 143 ? 12.862  -48.176 30.202  1.00 54.79  ? 350 ILE G CG1  1 
ATOM   10079 C  CG2  . ILE G 1 143 ? 14.740  -47.750 31.748  1.00 52.00  ? 350 ILE G CG2  1 
ATOM   10080 C  CD1  . ILE G 1 143 ? 13.075  -49.667 30.173  1.00 55.65  ? 350 ILE G CD1  1 
ATOM   10081 N  N    . GLN G 1 144 ? 15.314  -44.640 31.882  1.00 56.37  ? 351 GLN G N    1 
ATOM   10082 C  CA   . GLN G 1 144 ? 16.493  -43.930 32.352  1.00 57.59  ? 351 GLN G CA   1 
ATOM   10083 C  C    . GLN G 1 144 ? 17.346  -44.895 33.159  1.00 62.31  ? 351 GLN G C    1 
ATOM   10084 O  O    . GLN G 1 144 ? 16.890  -45.424 34.178  1.00 66.67  ? 351 GLN G O    1 
ATOM   10085 C  CB   . GLN G 1 144 ? 16.099  -42.714 33.194  1.00 57.86  ? 351 GLN G CB   1 
ATOM   10086 C  CG   . GLN G 1 144 ? 15.593  -41.510 32.367  1.00 55.13  ? 351 GLN G CG   1 
ATOM   10087 C  CD   . GLN G 1 144 ? 14.225  -41.739 31.759  1.00 57.66  ? 351 GLN G CD   1 
ATOM   10088 O  OE1  . GLN G 1 144 ? 13.361  -42.370 32.376  1.00 64.05  ? 351 GLN G OE1  1 
ATOM   10089 N  NE2  . GLN G 1 144 ? 14.012  -41.229 30.547  1.00 56.21  ? 351 GLN G NE2  1 
ATOM   10090 N  N    . LEU G 1 145 ? 18.564  -45.130 32.674  1.00 64.98  ? 352 LEU G N    1 
ATOM   10091 C  CA   . LEU G 1 145 ? 19.428  -46.165 33.287  1.00 65.40  ? 352 LEU G CA   1 
ATOM   10092 C  C    . LEU G 1 145 ? 20.666  -45.556 33.942  1.00 63.75  ? 352 LEU G C    1 
ATOM   10093 O  O    . LEU G 1 145 ? 21.442  -44.922 33.231  1.00 64.06  ? 352 LEU G O    1 
ATOM   10094 C  CB   . LEU G 1 145 ? 19.828  -47.114 32.156  1.00 63.97  ? 352 LEU G CB   1 
ATOM   10095 C  CG   . LEU G 1 145 ? 18.746  -48.068 31.658  1.00 65.42  ? 352 LEU G CG   1 
ATOM   10096 C  CD1  . LEU G 1 145 ? 19.164  -48.691 30.340  1.00 61.14  ? 352 LEU G CD1  1 
ATOM   10097 C  CD2  . LEU G 1 145 ? 18.463  -49.150 32.685  1.00 59.45  ? 352 LEU G CD2  1 
ATOM   10098 N  N    . SER G 1 146 ? 20.865  -45.812 35.235  1.00 64.18  ? 353 SER G N    1 
ATOM   10099 C  CA   . SER G 1 146 ? 22.044  -45.328 35.940  1.00 66.02  ? 353 SER G CA   1 
ATOM   10100 C  C    . SER G 1 146 ? 23.328  -45.871 35.295  1.00 74.48  ? 353 SER G C    1 
ATOM   10101 O  O    . SER G 1 146 ? 23.442  -47.071 35.017  1.00 70.84  ? 353 SER G O    1 
ATOM   10102 C  CB   . SER G 1 146 ? 21.960  -45.732 37.412  1.00 65.44  ? 353 SER G CB   1 
ATOM   10103 O  OG   . SER G 1 146 ? 23.238  -45.684 38.034  1.00 80.48  ? 353 SER G OG   1 
ATOM   10104 N  N    . ILE G 1 147 ? 24.292  -44.983 35.049  1.00 74.05  ? 354 ILE G N    1 
ATOM   10105 C  CA   . ILE G 1 147 ? 25.547  -45.343 34.378  1.00 72.67  ? 354 ILE G CA   1 
ATOM   10106 C  C    . ILE G 1 147 ? 26.692  -45.465 35.366  1.00 76.09  ? 354 ILE G C    1 
ATOM   10107 O  O    . ILE G 1 147 ? 27.466  -46.423 35.319  1.00 78.07  ? 354 ILE G O    1 
ATOM   10108 C  CB   . ILE G 1 147 ? 25.882  -44.315 33.277  1.00 70.40  ? 354 ILE G CB   1 
ATOM   10109 C  CG1  . ILE G 1 147 ? 24.795  -44.309 32.204  1.00 68.30  ? 354 ILE G CG1  1 
ATOM   10110 C  CG2  . ILE G 1 147 ? 27.226  -44.614 32.662  1.00 73.03  ? 354 ILE G CG2  1 
ATOM   10111 C  CD1  . ILE G 1 147 ? 24.695  -45.610 31.456  1.00 67.27  ? 354 ILE G CD1  1 
ATOM   10112 N  N    . LYS G 1 148 ? 26.798  -44.505 36.278  1.00 76.09  ? 355 LYS G N    1 
ATOM   10113 C  CA   . LYS G 1 148 ? 27.955  -44.417 37.154  1.00 72.80  ? 355 LYS G CA   1 
ATOM   10114 C  C    . LYS G 1 148 ? 28.016  -45.617 38.081  1.00 74.72  ? 355 LYS G C    1 
ATOM   10115 O  O    . LYS G 1 148 ? 27.087  -45.864 38.858  1.00 71.92  ? 355 LYS G O    1 
ATOM   10116 C  CB   . LYS G 1 148 ? 27.912  -43.121 37.962  1.00 70.08  ? 355 LYS G CB   1 
ATOM   10117 C  CG   . LYS G 1 148 ? 29.272  -42.705 38.506  1.00 68.86  ? 355 LYS G CG   1 
ATOM   10118 N  N    . GLY G 1 149 ? 29.114  -46.371 37.998  1.00 76.87  ? 356 GLY G N    1 
ATOM   10119 C  CA   . GLY G 1 149 ? 29.322  -47.515 38.909  1.00 80.24  ? 356 GLY G CA   1 
ATOM   10120 C  C    . GLY G 1 149 ? 28.928  -48.838 38.289  1.00 80.38  ? 356 GLY G C    1 
ATOM   10121 O  O    . GLY G 1 149 ? 29.019  -49.855 38.993  1.00 82.36  ? 356 GLY G O    1 
ATOM   10122 N  N    . LYS G 1 150 ? 28.528  -48.832 37.024  1.00 75.15  ? 357 LYS G N    1 
ATOM   10123 C  CA   . LYS G 1 150 ? 28.045  -50.022 36.350  1.00 73.31  ? 357 LYS G CA   1 
ATOM   10124 C  C    . LYS G 1 150 ? 28.923  -50.254 35.138  1.00 77.02  ? 357 LYS G C    1 
ATOM   10125 O  O    . LYS G 1 150 ? 29.294  -49.297 34.453  1.00 81.18  ? 357 LYS G O    1 
ATOM   10126 C  CB   . LYS G 1 150 ? 26.575  -49.862 35.923  1.00 75.96  ? 357 LYS G CB   1 
ATOM   10127 N  N    . LYS G 1 151 ? 29.264  -51.521 34.876  1.00 78.34  ? 358 LYS G N    1 
ATOM   10128 C  CA   . LYS G 1 151 ? 30.117  -51.819 33.727  1.00 76.69  ? 358 LYS G CA   1 
ATOM   10129 C  C    . LYS G 1 151 ? 29.320  -51.876 32.429  1.00 71.13  ? 358 LYS G C    1 
ATOM   10130 O  O    . LYS G 1 151 ? 29.800  -51.425 31.384  1.00 74.13  ? 358 LYS G O    1 
ATOM   10131 C  CB   . LYS G 1 151 ? 30.874  -53.131 33.943  1.00 75.44  ? 358 LYS G CB   1 
ATOM   10132 N  N    . ASN G 1 152 ? 28.147  -52.499 32.518  1.00 74.54  ? 359 ASN G N    1 
ATOM   10133 C  CA   . ASN G 1 152 ? 27.343  -52.742 31.300  1.00 74.37  ? 359 ASN G CA   1 
ATOM   10134 C  C    . ASN G 1 152 ? 25.856  -52.465 31.516  1.00 76.01  ? 359 ASN G C    1 
ATOM   10135 O  O    . ASN G 1 152 ? 25.438  -52.338 32.673  1.00 72.06  ? 359 ASN G O    1 
ATOM   10136 C  CB   . ASN G 1 152 ? 27.483  -54.194 30.843  1.00 74.24  ? 359 ASN G CB   1 
ATOM   10137 C  CG   . ASN G 1 152 ? 27.575  -55.193 31.977  1.00 76.89  ? 359 ASN G CG   1 
ATOM   10138 O  OD1  . ASN G 1 152 ? 26.849  -55.101 32.960  1.00 77.92  ? 359 ASN G OD1  1 
ATOM   10139 N  ND2  . ASN G 1 152 ? 28.459  -56.165 31.844  1.00 75.90  ? 359 ASN G ND2  1 
ATOM   10140 N  N    . ILE G 1 153 ? 25.091  -52.399 30.424  1.00 74.77  ? 360 ILE G N    1 
ATOM   10141 C  CA   . ILE G 1 153 ? 23.643  -52.201 30.514  1.00 74.03  ? 360 ILE G CA   1 
ATOM   10142 C  C    . ILE G 1 153 ? 22.973  -53.312 31.322  1.00 75.87  ? 360 ILE G C    1 
ATOM   10143 O  O    . ILE G 1 153 ? 21.944  -53.084 31.978  1.00 75.40  ? 360 ILE G O    1 
ATOM   10144 C  CB   . ILE G 1 153 ? 23.049  -52.088 29.101  1.00 72.47  ? 360 ILE G CB   1 
ATOM   10145 C  CG1  . ILE G 1 153 ? 21.546  -51.881 29.165  1.00 69.10  ? 360 ILE G CG1  1 
ATOM   10146 C  CG2  . ILE G 1 153 ? 23.311  -53.344 28.327  1.00 73.75  ? 360 ILE G CG2  1 
ATOM   10147 C  CD1  . ILE G 1 153 ? 20.916  -51.871 27.802  1.00 74.59  ? 360 ILE G CD1  1 
ATOM   10148 N  N    . PHE G 1 154 ? 23.539  -54.520 31.302  1.00 71.36  ? 361 PHE G N    1 
ATOM   10149 C  CA   . PHE G 1 154 ? 23.098  -55.559 32.222  1.00 70.19  ? 361 PHE G CA   1 
ATOM   10150 C  C    . PHE G 1 154 ? 23.085  -55.040 33.656  1.00 69.76  ? 361 PHE G C    1 
ATOM   10151 O  O    . PHE G 1 154 ? 22.058  -55.088 34.342  1.00 71.60  ? 361 PHE G O    1 
ATOM   10152 N  N    . GLU G 1 155 ? 24.212  -54.521 34.123  1.00 70.32  ? 362 GLU G N    1 
ATOM   10153 C  CA   . GLU G 1 155 ? 24.287  -54.105 35.547  1.00 70.69  ? 362 GLU G CA   1 
ATOM   10154 C  C    . GLU G 1 155 ? 23.381  -52.896 35.804  1.00 66.01  ? 362 GLU G C    1 
ATOM   10155 O  O    . GLU G 1 155 ? 22.925  -52.757 36.941  1.00 66.76  ? 362 GLU G O    1 
ATOM   10156 C  CB   . GLU G 1 155 ? 25.737  -53.827 35.937  1.00 73.89  ? 362 GLU G CB   1 
ATOM   10157 C  CG   . GLU G 1 155 ? 26.521  -55.077 36.287  1.00 79.33  ? 362 GLU G CG   1 
ATOM   10158 C  CD   . GLU G 1 155 ? 28.030  -54.934 36.183  1.00 82.10  ? 362 GLU G CD   1 
ATOM   10159 O  OE1  . GLU G 1 155 ? 28.558  -53.894 36.620  1.00 83.18  ? 362 GLU G OE1  1 
ATOM   10160 O  OE2  . GLU G 1 155 ? 28.675  -55.864 35.665  1.00 74.13  ? 362 GLU G OE2  1 
ATOM   10161 N  N    . SER G 1 156 ? 23.129  -52.064 34.797  1.00 62.92  ? 363 SER G N    1 
ATOM   10162 C  CA   . SER G 1 156 ? 22.210  -50.952 35.008  1.00 67.62  ? 363 SER G CA   1 
ATOM   10163 C  C    . SER G 1 156 ? 20.787  -51.460 35.259  1.00 71.54  ? 363 SER G C    1 
ATOM   10164 O  O    . SER G 1 156 ? 20.131  -51.060 36.231  1.00 67.89  ? 363 SER G O    1 
ATOM   10165 C  CB   . SER G 1 156 ? 22.252  -50.014 33.803  1.00 68.23  ? 363 SER G CB   1 
ATOM   10166 O  OG   . SER G 1 156 ? 21.689  -48.759 34.125  1.00 67.01  ? 363 SER G OG   1 
ATOM   10167 N  N    . PHE G 1 157 ? 20.303  -52.363 34.400  1.00 67.93  ? 364 PHE G N    1 
ATOM   10168 C  CA   . PHE G 1 157 ? 18.983  -52.957 34.597  1.00 65.69  ? 364 PHE G CA   1 
ATOM   10169 C  C    . PHE G 1 157 ? 18.864  -53.660 35.946  1.00 66.46  ? 364 PHE G C    1 
ATOM   10170 O  O    . PHE G 1 157 ? 17.818  -53.572 36.601  1.00 68.46  ? 364 PHE G O    1 
ATOM   10171 C  CB   . PHE G 1 157 ? 18.687  -53.940 33.477  1.00 63.52  ? 364 PHE G CB   1 
ATOM   10172 C  CG   . PHE G 1 157 ? 17.945  -53.346 32.345  1.00 55.70  ? 364 PHE G CG   1 
ATOM   10173 C  CD1  . PHE G 1 157 ? 16.585  -53.121 32.437  1.00 58.16  ? 364 PHE G CD1  1 
ATOM   10174 C  CD2  . PHE G 1 157 ? 18.598  -53.020 31.184  1.00 57.03  ? 364 PHE G CD2  1 
ATOM   10175 C  CE1  . PHE G 1 157 ? 15.887  -52.581 31.379  1.00 56.97  ? 364 PHE G CE1  1 
ATOM   10176 C  CE2  . PHE G 1 157 ? 17.903  -52.475 30.129  1.00 62.12  ? 364 PHE G CE2  1 
ATOM   10177 C  CZ   . PHE G 1 157 ? 16.546  -52.252 30.229  1.00 56.43  ? 364 PHE G CZ   1 
ATOM   10178 N  N    . VAL G 1 158 ? 19.908  -54.378 36.371  1.00 59.11  ? 365 VAL G N    1 
ATOM   10179 C  CA   . VAL G 1 158 ? 19.879  -54.992 37.698  1.00 62.14  ? 365 VAL G CA   1 
ATOM   10180 C  C    . VAL G 1 158 ? 19.708  -53.932 38.775  1.00 61.65  ? 365 VAL G C    1 
ATOM   10181 O  O    . VAL G 1 158 ? 18.887  -54.080 39.688  1.00 63.77  ? 365 VAL G O    1 
ATOM   10182 C  CB   . VAL G 1 158 ? 21.152  -55.817 37.945  1.00 66.31  ? 365 VAL G CB   1 
ATOM   10183 C  CG1  . VAL G 1 158 ? 21.200  -56.304 39.403  1.00 53.55  ? 365 VAL G CG1  1 
ATOM   10184 C  CG2  . VAL G 1 158 ? 21.210  -56.968 36.995  1.00 65.59  ? 365 VAL G CG2  1 
ATOM   10185 N  N    . ASP G 1 159 ? 20.511  -52.862 38.709  1.00 66.80  ? 366 ASP G N    1 
ATOM   10186 C  CA   . ASP G 1 159 ? 20.381  -51.783 39.686  1.00 63.76  ? 366 ASP G CA   1 
ATOM   10187 C  C    . ASP G 1 159 ? 18.994  -51.175 39.615  1.00 60.38  ? 366 ASP G C    1 
ATOM   10188 O  O    . ASP G 1 159 ? 18.391  -50.863 40.651  1.00 59.97  ? 366 ASP G O    1 
ATOM   10189 C  CB   . ASP G 1 159 ? 21.454  -50.707 39.457  1.00 65.23  ? 366 ASP G CB   1 
ATOM   10190 C  CG   . ASP G 1 159 ? 21.496  -49.657 40.587  1.00 73.27  ? 366 ASP G CG   1 
ATOM   10191 O  OD1  . ASP G 1 159 ? 21.247  -50.032 41.757  1.00 78.37  ? 366 ASP G OD1  1 
ATOM   10192 O  OD2  . ASP G 1 159 ? 21.773  -48.459 40.317  1.00 72.17  ? 366 ASP G OD2  1 
ATOM   10193 N  N    . TYR G 1 160 ? 18.455  -51.061 38.393  1.00 58.44  ? 367 TYR G N    1 
ATOM   10194 C  CA   . TYR G 1 160 ? 17.161  -50.425 38.171  1.00 58.46  ? 367 TYR G CA   1 
ATOM   10195 C  C    . TYR G 1 160 ? 16.057  -51.079 38.994  1.00 61.16  ? 367 TYR G C    1 
ATOM   10196 O  O    . TYR G 1 160 ? 15.155  -50.395 39.488  1.00 56.30  ? 367 TYR G O    1 
ATOM   10197 C  CB   . TYR G 1 160 ? 16.809  -50.473 36.685  1.00 56.49  ? 367 TYR G CB   1 
ATOM   10198 C  CG   . TYR G 1 160 ? 15.662  -49.567 36.306  1.00 58.62  ? 367 TYR G CG   1 
ATOM   10199 C  CD1  . TYR G 1 160 ? 14.345  -49.895 36.624  1.00 59.63  ? 367 TYR G CD1  1 
ATOM   10200 C  CD2  . TYR G 1 160 ? 15.891  -48.378 35.624  1.00 61.72  ? 367 TYR G CD2  1 
ATOM   10201 C  CE1  . TYR G 1 160 ? 13.286  -49.051 36.271  1.00 60.96  ? 367 TYR G CE1  1 
ATOM   10202 C  CE2  . TYR G 1 160 ? 14.850  -47.537 35.267  1.00 61.05  ? 367 TYR G CE2  1 
ATOM   10203 C  CZ   . TYR G 1 160 ? 13.549  -47.875 35.594  1.00 64.59  ? 367 TYR G CZ   1 
ATOM   10204 O  OH   . TYR G 1 160 ? 12.525  -47.017 35.244  1.00 67.25  ? 367 TYR G OH   1 
ATOM   10205 N  N    . VAL G 1 161 ? 16.098  -52.400 39.146  1.00 62.12  ? 368 VAL G N    1 
ATOM   10206 C  CA   . VAL G 1 161 ? 15.054  -53.106 39.867  1.00 56.60  ? 368 VAL G CA   1 
ATOM   10207 C  C    . VAL G 1 161 ? 15.529  -53.579 41.225  1.00 55.97  ? 368 VAL G C    1 
ATOM   10208 O  O    . VAL G 1 161 ? 14.858  -54.388 41.854  1.00 65.87  ? 368 VAL G O    1 
ATOM   10209 C  CB   . VAL G 1 161 ? 14.478  -54.267 39.042  1.00 60.46  ? 368 VAL G CB   1 
ATOM   10210 C  CG1  . VAL G 1 161 ? 14.063  -53.754 37.657  1.00 58.47  ? 368 VAL G CG1  1 
ATOM   10211 C  CG2  . VAL G 1 161 ? 15.467  -55.414 38.940  1.00 59.76  ? 368 VAL G CG2  1 
ATOM   10212 N  N    . ALA G 1 162 ? 16.641  -53.053 41.721  1.00 58.70  ? 369 ALA G N    1 
ATOM   10213 C  CA   . ALA G 1 162 ? 17.059  -53.370 43.083  1.00 60.42  ? 369 ALA G CA   1 
ATOM   10214 C  C    . ALA G 1 162 ? 16.096  -52.784 44.099  1.00 60.88  ? 369 ALA G C    1 
ATOM   10215 O  O    . ALA G 1 162 ? 15.464  -51.748 43.867  1.00 67.09  ? 369 ALA G O    1 
ATOM   10216 C  CB   . ALA G 1 162 ? 18.452  -52.819 43.364  1.00 57.84  ? 369 ALA G CB   1 
ATOM   10217 N  N    . VAL G 1 163 ? 15.998  -53.444 45.250  1.00 63.48  ? 370 VAL G N    1 
ATOM   10218 C  CA   . VAL G 1 163 ? 15.219  -52.890 46.350  1.00 62.08  ? 370 VAL G CA   1 
ATOM   10219 C  C    . VAL G 1 163 ? 15.976  -51.719 46.959  1.00 63.99  ? 370 VAL G C    1 
ATOM   10220 O  O    . VAL G 1 163 ? 17.203  -51.765 47.113  1.00 66.95  ? 370 VAL G O    1 
ATOM   10221 C  CB   . VAL G 1 163 ? 14.918  -53.972 47.403  1.00 62.69  ? 370 VAL G CB   1 
ATOM   10222 C  CG1  . VAL G 1 163 ? 16.201  -54.459 48.064  1.00 68.66  ? 370 VAL G CG1  1 
ATOM   10223 C  CG2  . VAL G 1 163 ? 13.958  -53.432 48.462  1.00 65.93  ? 370 VAL G CG2  1 
ATOM   10224 N  N    . GLU G 1 164 ? 15.257  -50.645 47.281  1.00 64.65  ? 371 GLU G N    1 
ATOM   10225 C  CA   . GLU G 1 164 ? 15.854  -49.521 47.986  1.00 63.17  ? 371 GLU G CA   1 
ATOM   10226 C  C    . GLU G 1 164 ? 15.178  -49.333 49.337  1.00 68.73  ? 371 GLU G C    1 
ATOM   10227 O  O    . GLU G 1 164 ? 14.049  -49.787 49.566  1.00 64.62  ? 371 GLU G O    1 
ATOM   10228 C  CB   . GLU G 1 164 ? 15.733  -48.205 47.228  1.00 54.60  ? 371 GLU G CB   1 
ATOM   10229 C  CG   . GLU G 1 164 ? 15.592  -48.282 45.764  1.00 60.71  ? 371 GLU G CG   1 
ATOM   10230 C  CD   . GLU G 1 164 ? 15.203  -46.922 45.193  1.00 68.74  ? 371 GLU G CD   1 
ATOM   10231 O  OE1  . GLU G 1 164 ? 15.738  -45.907 45.698  1.00 64.05  ? 371 GLU G OE1  1 
ATOM   10232 O  OE2  . GLU G 1 164 ? 14.372  -46.863 44.253  1.00 70.20  ? 371 GLU G OE2  1 
ATOM   10233 N  N    . GLN G 1 165 ? 15.865  -48.619 50.223  1.00 63.23  ? 372 GLN G N    1 
ATOM   10234 C  CA   . GLN G 1 165 ? 15.301  -48.284 51.521  1.00 65.02  ? 372 GLN G CA   1 
ATOM   10235 C  C    . GLN G 1 165 ? 14.766  -46.855 51.503  1.00 61.51  ? 372 GLN G C    1 
ATOM   10236 O  O    . GLN G 1 165 ? 15.417  -45.942 50.992  1.00 64.04  ? 372 GLN G O    1 
ATOM   10237 C  CB   . GLN G 1 165 ? 16.335  -48.472 52.634  1.00 67.35  ? 372 GLN G CB   1 
ATOM   10238 C  CG   . GLN G 1 165 ? 17.079  -49.823 52.609  1.00 70.32  ? 372 GLN G CG   1 
ATOM   10239 C  CD   . GLN G 1 165 ? 16.146  -51.023 52.559  1.00 69.89  ? 372 GLN G CD   1 
ATOM   10240 O  OE1  . GLN G 1 165 ? 16.192  -51.809 51.617  1.00 68.80  ? 372 GLN G OE1  1 
ATOM   10241 N  NE2  . GLN G 1 165 ? 15.296  -51.165 53.570  1.00 66.22  ? 372 GLN G NE2  1 
ATOM   10242 N  N    . LEU G 1 166 ? 13.570  -46.671 52.027  1.00 60.47  ? 373 LEU G N    1 
ATOM   10243 C  CA   . LEU G 1 166 ? 12.988  -45.349 52.175  1.00 57.08  ? 373 LEU G CA   1 
ATOM   10244 C  C    . LEU G 1 166 ? 13.027  -45.053 53.665  1.00 58.92  ? 373 LEU G C    1 
ATOM   10245 O  O    . LEU G 1 166 ? 12.150  -45.498 54.406  1.00 64.83  ? 373 LEU G O    1 
ATOM   10246 C  CB   . LEU G 1 166 ? 11.578  -45.302 51.600  1.00 54.81  ? 373 LEU G CB   1 
ATOM   10247 C  CG   . LEU G 1 166 ? 11.486  -45.500 50.081  1.00 56.95  ? 373 LEU G CG   1 
ATOM   10248 C  CD1  . LEU G 1 166 ? 10.043  -45.671 49.602  1.00 60.24  ? 373 LEU G CD1  1 
ATOM   10249 C  CD2  . LEU G 1 166 ? 12.149  -44.357 49.348  1.00 48.22  ? 373 LEU G CD2  1 
ATOM   10250 N  N    . ASP G 1 167 ? 14.062  -44.326 54.106  1.00 60.70  ? 374 ASP G N    1 
ATOM   10251 C  CA   . ASP G 1 167 ? 14.259  -44.007 55.519  1.00 61.52  ? 374 ASP G CA   1 
ATOM   10252 C  C    . ASP G 1 167 ? 14.828  -42.592 55.657  1.00 66.11  ? 374 ASP G C    1 
ATOM   10253 O  O    . ASP G 1 167 ? 15.034  -41.874 54.670  1.00 64.94  ? 374 ASP G O    1 
ATOM   10254 C  CB   . ASP G 1 167 ? 15.184  -45.028 56.192  1.00 58.77  ? 374 ASP G CB   1 
ATOM   10255 C  CG   . ASP G 1 167 ? 16.487  -45.222 55.418  1.00 70.76  ? 374 ASP G CG   1 
ATOM   10256 O  OD1  . ASP G 1 167 ? 16.991  -44.236 54.831  1.00 69.22  ? 374 ASP G OD1  1 
ATOM   10257 O  OD2  . ASP G 1 167 ? 17.011  -46.352 55.392  1.00 71.03  ? 374 ASP G OD2  1 
ATOM   10258 N  N    . GLY G 1 168 ? 15.090  -42.199 56.905  1.00 63.25  ? 375 GLY G N    1 
ATOM   10259 C  CA   . GLY G 1 168 ? 15.611  -40.887 57.213  1.00 61.07  ? 375 GLY G CA   1 
ATOM   10260 C  C    . GLY G 1 168 ? 14.757  -39.766 56.665  1.00 65.90  ? 375 GLY G C    1 
ATOM   10261 O  O    . GLY G 1 168 ? 13.647  -39.532 57.159  1.00 67.08  ? 375 GLY G O    1 
ATOM   10262 N  N    . ASP G 1 169 ? 15.256  -39.063 55.645  1.00 63.44  ? 376 ASP G N    1 
ATOM   10263 C  CA   . ASP G 1 169 ? 14.530  -37.933 55.079  1.00 63.46  ? 376 ASP G CA   1 
ATOM   10264 C  C    . ASP G 1 169 ? 13.628  -38.333 53.918  1.00 59.56  ? 376 ASP G C    1 
ATOM   10265 O  O    . ASP G 1 169 ? 13.051  -37.456 53.267  1.00 61.25  ? 376 ASP G O    1 
ATOM   10266 C  CB   . ASP G 1 169 ? 15.501  -36.827 54.636  1.00 62.32  ? 376 ASP G CB   1 
ATOM   10267 C  CG   . ASP G 1 169 ? 14.832  -35.448 54.591  1.00 61.72  ? 376 ASP G CG   1 
ATOM   10268 O  OD1  . ASP G 1 169 ? 13.980  -35.166 55.472  1.00 57.31  ? 376 ASP G OD1  1 
ATOM   10269 O  OD2  . ASP G 1 169 ? 15.134  -34.661 53.658  1.00 59.28  ? 376 ASP G OD2  1 
ATOM   10270 N  N    . ASN G 1 170 ? 13.538  -39.631 53.664  1.00 62.45  ? 377 ASN G N    1 
ATOM   10271 C  CA   . ASN G 1 170 ? 12.715  -40.140 52.544  1.00 61.71  ? 377 ASN G CA   1 
ATOM   10272 C  C    . ASN G 1 170 ? 11.869  -41.295 53.066  1.00 62.01  ? 377 ASN G C    1 
ATOM   10273 O  O    . ASN G 1 170 ? 11.762  -42.289 52.370  1.00 59.00  ? 377 ASN G O    1 
ATOM   10274 C  CB   . ASN G 1 170 ? 13.587  -40.528 51.353  1.00 61.39  ? 377 ASN G CB   1 
ATOM   10275 C  CG   . ASN G 1 170 ? 14.392  -39.371 50.817  1.00 59.08  ? 377 ASN G CG   1 
ATOM   10276 O  OD1  . ASN G 1 170 ? 13.835  -38.475 50.203  1.00 57.70  ? 377 ASN G OD1  1 
ATOM   10277 N  ND2  . ASN G 1 170 ? 15.690  -39.376 51.064  1.00 47.30  ? 377 ASN G ND2  1 
ATOM   10278 N  N    . LYS G 1 171 ? 11.276  -41.128 54.245  1.00 63.31  ? 378 LYS G N    1 
ATOM   10279 C  CA   . LYS G 1 171 ? 10.399  -42.165 54.841  1.00 59.79  ? 378 LYS G CA   1 
ATOM   10280 C  C    . LYS G 1 171 ? 9.076   -42.237 54.075  1.00 62.20  ? 378 LYS G C    1 
ATOM   10281 O  O    . LYS G 1 171 ? 8.597   -41.190 53.621  1.00 55.41  ? 378 LYS G O    1 
ATOM   10282 C  CB   . LYS G 1 171 ? 10.185  -41.841 56.320  1.00 58.80  ? 378 LYS G CB   1 
ATOM   10283 N  N    . TYR G 1 172 ? 8.487   -43.430 53.977  1.00 63.61  ? 379 TYR G N    1 
ATOM   10284 C  CA   . TYR G 1 172 ? 7.281   -43.606 53.177  1.00 61.77  ? 379 TYR G CA   1 
ATOM   10285 C  C    . TYR G 1 172 ? 6.058   -43.099 53.928  1.00 59.23  ? 379 TYR G C    1 
ATOM   10286 O  O    . TYR G 1 172 ? 5.902   -43.352 55.123  1.00 62.61  ? 379 TYR G O    1 
ATOM   10287 C  CB   . TYR G 1 172 ? 7.102   -45.087 52.821  1.00 66.47  ? 379 TYR G CB   1 
ATOM   10288 C  CG   . TYR G 1 172 ? 5.792   -45.391 52.148  1.00 58.10  ? 379 TYR G CG   1 
ATOM   10289 C  CD1  . TYR G 1 172 ? 5.497   -44.846 50.907  1.00 62.25  ? 379 TYR G CD1  1 
ATOM   10290 C  CD2  . TYR G 1 172 ? 4.840   -46.207 52.759  1.00 59.29  ? 379 TYR G CD2  1 
ATOM   10291 C  CE1  . TYR G 1 172 ? 4.289   -45.106 50.272  1.00 60.86  ? 379 TYR G CE1  1 
ATOM   10292 C  CE2  . TYR G 1 172 ? 3.624   -46.468 52.138  1.00 57.91  ? 379 TYR G CE2  1 
ATOM   10293 C  CZ   . TYR G 1 172 ? 3.367   -45.918 50.889  1.00 58.35  ? 379 TYR G CZ   1 
ATOM   10294 O  OH   . TYR G 1 172 ? 2.194   -46.158 50.242  1.00 57.15  ? 379 TYR G OH   1 
ATOM   10295 N  N    . ASP G 1 173 ? 5.182   -42.385 53.230  1.00 57.57  ? 380 ASP G N    1 
ATOM   10296 C  CA   . ASP G 1 173 ? 3.954   -41.892 53.854  1.00 60.82  ? 380 ASP G CA   1 
ATOM   10297 C  C    . ASP G 1 173 ? 2.890   -42.988 53.782  1.00 64.16  ? 380 ASP G C    1 
ATOM   10298 O  O    . ASP G 1 173 ? 2.285   -43.210 52.728  1.00 58.78  ? 380 ASP G O    1 
ATOM   10299 C  CB   . ASP G 1 173 ? 3.470   -40.622 53.169  1.00 57.15  ? 380 ASP G CB   1 
ATOM   10300 C  CG   . ASP G 1 173 ? 2.062   -40.231 53.608  1.00 67.06  ? 380 ASP G CG   1 
ATOM   10301 O  OD1  . ASP G 1 173 ? 1.771   -40.345 54.817  1.00 67.77  ? 380 ASP G OD1  1 
ATOM   10302 O  OD2  . ASP G 1 173 ? 1.244   -39.825 52.749  1.00 73.20  ? 380 ASP G OD2  1 
ATOM   10303 N  N    . ALA G 1 174 ? 2.647   -43.672 54.902  1.00 59.80  ? 381 ALA G N    1 
ATOM   10304 C  CA   . ALA G 1 174 ? 1.776   -44.846 54.934  1.00 61.71  ? 381 ALA G CA   1 
ATOM   10305 C  C    . ALA G 1 174 ? 0.453   -44.576 55.658  1.00 65.54  ? 381 ALA G C    1 
ATOM   10306 O  O    . ALA G 1 174 ? -0.023  -45.391 56.452  1.00 64.66  ? 381 ALA G O    1 
ATOM   10307 C  CB   . ALA G 1 174 ? 2.506   -46.032 55.559  1.00 64.44  ? 381 ALA G CB   1 
ATOM   10308 N  N    . GLY G 1 175 ? -0.148  -43.417 55.394  1.00 70.85  ? 382 GLY G N    1 
ATOM   10309 C  CA   . GLY G 1 175 ? -1.512  -43.158 55.851  1.00 72.88  ? 382 GLY G CA   1 
ATOM   10310 C  C    . GLY G 1 175 ? -1.643  -43.068 57.362  1.00 69.03  ? 382 GLY G C    1 
ATOM   10311 O  O    . GLY G 1 175 ? -0.868  -42.388 58.043  1.00 73.57  ? 382 GLY G O    1 
ATOM   10312 N  N    . GLU G 1 176 ? -2.655  -43.760 57.891  1.00 67.11  ? 383 GLU G N    1 
ATOM   10313 C  CA   . GLU G 1 176 ? -2.880  -43.809 59.330  1.00 66.74  ? 383 GLU G CA   1 
ATOM   10314 C  C    . GLU G 1 176 ? -1.636  -44.220 60.107  1.00 70.15  ? 383 GLU G C    1 
ATOM   10315 O  O    . GLU G 1 176 ? -1.542  -43.920 61.302  1.00 73.29  ? 383 GLU G O    1 
ATOM   10316 N  N    . HIS G 1 177 ? -0.665  -44.848 59.445  1.00 69.44  ? 384 HIS G N    1 
ATOM   10317 C  CA   . HIS G 1 177 ? 0.603   -45.224 60.128  1.00 72.31  ? 384 HIS G CA   1 
ATOM   10318 C  C    . HIS G 1 177 ? 1.599   -44.062 60.087  1.00 68.85  ? 384 HIS G C    1 
ATOM   10319 O  O    . HIS G 1 177 ? 2.625   -44.152 60.771  1.00 61.55  ? 384 HIS G O    1 
ATOM   10320 C  CB   . HIS G 1 177 ? 1.204   -46.483 59.499  1.00 67.64  ? 384 HIS G CB   1 
ATOM   10321 C  CG   . HIS G 1 177 ? 0.374   -47.710 59.642  1.00 72.21  ? 384 HIS G CG   1 
ATOM   10322 N  ND1  . HIS G 1 177 ? 0.224   -48.361 60.845  1.00 77.00  ? 384 HIS G ND1  1 
ATOM   10323 C  CD2  . HIS G 1 177 ? -0.329  -48.417 58.734  1.00 70.73  ? 384 HIS G CD2  1 
ATOM   10324 C  CE1  . HIS G 1 177 ? -0.545  -49.414 60.675  1.00 74.30  ? 384 HIS G CE1  1 
ATOM   10325 N  NE2  . HIS G 1 177 ? -0.899  -49.469 59.389  1.00 69.37  ? 384 HIS G NE2  1 
ATOM   10326 N  N    . GLY G 1 178 ? 1.298   -43.012 59.326  1.00 70.53  ? 385 GLY G N    1 
ATOM   10327 C  CA   . GLY G 1 178 ? 2.215   -41.877 59.155  1.00 69.81  ? 385 GLY G CA   1 
ATOM   10328 C  C    . GLY G 1 178 ? 3.453   -42.269 58.386  1.00 68.60  ? 385 GLY G C    1 
ATOM   10329 O  O    . GLY G 1 178 ? 3.411   -43.237 57.615  1.00 68.08  ? 385 GLY G O    1 
ATOM   10330 N  N    . LEU G 1 179 ? 4.528   -41.529 58.604  1.00 69.13  ? 386 LEU G N    1 
ATOM   10331 C  CA   . LEU G 1 179 ? 5.788   -41.845 57.946  1.00 68.86  ? 386 LEU G CA   1 
ATOM   10332 C  C    . LEU G 1 179 ? 6.385   -43.138 58.513  1.00 70.05  ? 386 LEU G C    1 
ATOM   10333 O  O    . LEU G 1 179 ? 6.364   -43.372 59.729  1.00 62.41  ? 386 LEU G O    1 
ATOM   10334 C  CB   . LEU G 1 179 ? 6.765   -40.670 58.087  1.00 63.25  ? 386 LEU G CB   1 
ATOM   10335 C  CG   . LEU G 1 179 ? 6.265   -39.358 57.452  1.00 65.67  ? 386 LEU G CG   1 
ATOM   10336 C  CD1  . LEU G 1 179 ? 7.165   -38.144 57.776  1.00 55.60  ? 386 LEU G CD1  1 
ATOM   10337 C  CD2  . LEU G 1 179 ? 6.088   -39.516 55.947  1.00 64.99  ? 386 LEU G CD2  1 
ATOM   10338 N  N    . GLN G 1 180 ? 6.921   -43.978 57.610  1.00 62.58  ? 387 GLN G N    1 
ATOM   10339 C  CA   . GLN G 1 180 ? 7.442   -45.295 57.949  1.00 61.48  ? 387 GLN G CA   1 
ATOM   10340 C  C    . GLN G 1 180 ? 8.713   -45.595 57.169  1.00 59.36  ? 387 GLN G C    1 
ATOM   10341 O  O    . GLN G 1 180 ? 8.867   -45.182 56.013  1.00 61.66  ? 387 GLN G O    1 
ATOM   10342 C  CB   . GLN G 1 180 ? 6.408   -46.394 57.648  1.00 66.51  ? 387 GLN G CB   1 
ATOM   10343 C  CG   . GLN G 1 180 ? 5.181   -46.327 58.531  1.00 60.72  ? 387 GLN G CG   1 
ATOM   10344 C  CD   . GLN G 1 180 ? 5.528   -46.619 59.968  1.00 63.36  ? 387 GLN G CD   1 
ATOM   10345 O  OE1  . GLN G 1 180 ? 6.489   -47.343 60.244  1.00 56.75  ? 387 GLN G OE1  1 
ATOM   10346 N  NE2  . GLN G 1 180 ? 4.754   -46.057 60.897  1.00 64.11  ? 387 GLN G NE2  1 
ATOM   10347 N  N    . GLU G 1 181 ? 9.624   -46.326 57.809  1.00 55.03  ? 388 GLU G N    1 
ATOM   10348 C  CA   . GLU G 1 181 ? 10.707  -46.959 57.066  1.00 58.72  ? 388 GLU G CA   1 
ATOM   10349 C  C    . GLU G 1 181 ? 10.116  -48.037 56.163  1.00 63.78  ? 388 GLU G C    1 
ATOM   10350 O  O    . GLU G 1 181 ? 9.179   -48.733 56.551  1.00 69.91  ? 388 GLU G O    1 
ATOM   10351 C  CB   . GLU G 1 181 ? 11.737  -47.559 58.028  1.00 51.19  ? 388 GLU G CB   1 
ATOM   10352 N  N    . ALA G 1 182 ? 10.634  -48.166 54.943  1.00 63.09  ? 389 ALA G N    1 
ATOM   10353 C  CA   . ALA G 1 182 ? 9.975   -49.070 54.004  1.00 66.35  ? 389 ALA G CA   1 
ATOM   10354 C  C    . ALA G 1 182 ? 10.942  -49.505 52.913  1.00 61.20  ? 389 ALA G C    1 
ATOM   10355 O  O    . ALA G 1 182 ? 11.978  -48.881 52.691  1.00 65.49  ? 389 ALA G O    1 
ATOM   10356 C  CB   . ALA G 1 182 ? 8.730   -48.414 53.382  1.00 64.10  ? 389 ALA G CB   1 
ATOM   10357 N  N    . GLU G 1 183 ? 10.586  -50.589 52.237  1.00 57.39  ? 390 GLU G N    1 
ATOM   10358 C  CA   . GLU G 1 183 ? 11.324  -51.063 51.073  1.00 61.61  ? 390 GLU G CA   1 
ATOM   10359 C  C    . GLU G 1 183 ? 10.548  -50.699 49.809  1.00 63.55  ? 390 GLU G C    1 
ATOM   10360 O  O    . GLU G 1 183 ? 9.313   -50.772 49.780  1.00 56.69  ? 390 GLU G O    1 
ATOM   10361 N  N    . LYS G 1 184 ? 11.301  -50.323 48.772  1.00 60.44  ? 391 LYS G N    1 
ATOM   10362 C  CA   . LYS G 1 184 ? 10.693  -49.999 47.462  1.00 55.57  ? 391 LYS G CA   1 
ATOM   10363 C  C    . LYS G 1 184 ? 11.445  -50.711 46.348  1.00 61.81  ? 391 LYS G C    1 
ATOM   10364 O  O    . LYS G 1 184 ? 12.671  -50.578 46.284  1.00 60.99  ? 391 LYS G O    1 
ATOM   10365 C  CB   . LYS G 1 184 ? 10.728  -48.505 47.145  1.00 57.18  ? 391 LYS G CB   1 
ATOM   10366 C  CG   . LYS G 1 184 ? 10.415  -48.128 45.702  1.00 56.23  ? 391 LYS G CG   1 
ATOM   10367 C  CD   . LYS G 1 184 ? 10.351  -46.644 45.461  1.00 55.52  ? 391 LYS G CD   1 
ATOM   10368 C  CE   . LYS G 1 184 ? 9.505   -46.282 44.261  1.00 63.68  ? 391 LYS G CE   1 
ATOM   10369 N  NZ   . LYS G 1 184 ? 10.336  -45.945 43.084  1.00 61.42  ? 391 LYS G NZ   1 
ATOM   10370 N  N    . GLY G 1 185 ? 10.728  -51.454 45.516  1.00 58.88  ? 392 GLY G N    1 
ATOM   10371 C  CA   . GLY G 1 185 ? 11.324  -52.059 44.344  1.00 52.12  ? 392 GLY G CA   1 
ATOM   10372 C  C    . GLY G 1 185 ? 10.463  -51.892 43.115  1.00 54.08  ? 392 GLY G C    1 
ATOM   10373 O  O    . GLY G 1 185 ? 9.242   -52.069 43.181  1.00 59.09  ? 392 GLY G O    1 
ATOM   10374 N  N    . VAL G 1 186 ? 11.082  -51.567 41.984  1.00 53.32  ? 393 VAL G N    1 
ATOM   10375 C  CA   . VAL G 1 186 ? 10.384  -51.446 40.710  1.00 56.05  ? 393 VAL G CA   1 
ATOM   10376 C  C    . VAL G 1 186 ? 10.683  -52.668 39.839  1.00 60.69  ? 393 VAL G C    1 
ATOM   10377 O  O    . VAL G 1 186 ? 11.721  -53.325 39.986  1.00 64.14  ? 393 VAL G O    1 
ATOM   10378 C  CB   . VAL G 1 186 ? 10.783  -50.123 40.015  1.00 56.56  ? 393 VAL G CB   1 
ATOM   10379 C  CG1  . VAL G 1 186 ? 10.071  -49.953 38.681  1.00 54.94  ? 393 VAL G CG1  1 
ATOM   10380 C  CG2  . VAL G 1 186 ? 10.459  -48.954 40.919  1.00 53.64  ? 393 VAL G CG2  1 
ATOM   10381 N  N    . LYS G 1 187 ? 9.748   -52.993 38.946  1.00 56.91  ? 394 LYS G N    1 
ATOM   10382 C  CA   . LYS G 1 187 ? 9.912   -54.082 37.988  1.00 58.17  ? 394 LYS G CA   1 
ATOM   10383 C  C    . LYS G 1 187 ? 9.046   -53.739 36.792  1.00 59.84  ? 394 LYS G C    1 
ATOM   10384 O  O    . LYS G 1 187 ? 8.120   -52.936 36.910  1.00 63.82  ? 394 LYS G O    1 
ATOM   10385 C  CB   . LYS G 1 187 ? 9.503   -55.442 38.573  1.00 57.96  ? 394 LYS G CB   1 
ATOM   10386 C  CG   . LYS G 1 187 ? 10.533  -56.090 39.503  1.00 63.94  ? 394 LYS G CG   1 
ATOM   10387 C  CD   . LYS G 1 187 ? 11.685  -56.738 38.718  1.00 62.10  ? 394 LYS G CD   1 
ATOM   10388 C  CE   . LYS G 1 187 ? 12.039  -58.097 39.316  1.00 63.50  ? 394 LYS G CE   1 
ATOM   10389 N  NZ   . LYS G 1 187 ? 10.804  -58.909 39.651  1.00 68.15  ? 394 LYS G NZ   1 
ATOM   10390 N  N    . PHE G 1 188 ? 9.348   -54.335 35.635  1.00 56.53  ? 395 PHE G N    1 
ATOM   10391 C  CA   . PHE G 1 188 ? 8.621   -54.031 34.405  1.00 57.47  ? 395 PHE G CA   1 
ATOM   10392 C  C    . PHE G 1 188 ? 7.513   -55.055 34.181  1.00 60.62  ? 395 PHE G C    1 
ATOM   10393 O  O    . PHE G 1 188 ? 7.718   -56.256 34.390  1.00 61.11  ? 395 PHE G O    1 
ATOM   10394 C  CB   . PHE G 1 188 ? 9.559   -54.023 33.195  1.00 58.86  ? 395 PHE G CB   1 
ATOM   10395 C  CG   . PHE G 1 188 ? 10.597  -52.968 33.258  1.00 58.07  ? 395 PHE G CG   1 
ATOM   10396 C  CD1  . PHE G 1 188 ? 10.345  -51.707 32.760  1.00 63.14  ? 395 PHE G CD1  1 
ATOM   10397 C  CD2  . PHE G 1 188 ? 11.822  -53.222 33.847  1.00 61.08  ? 395 PHE G CD2  1 
ATOM   10398 C  CE1  . PHE G 1 188 ? 11.298  -50.711 32.849  1.00 61.39  ? 395 PHE G CE1  1 
ATOM   10399 C  CE2  . PHE G 1 188 ? 12.785  -52.235 33.929  1.00 62.79  ? 395 PHE G CE2  1 
ATOM   10400 C  CZ   . PHE G 1 188 ? 12.520  -50.976 33.430  1.00 61.11  ? 395 PHE G CZ   1 
ATOM   10401 N  N    . LEU G 1 189 ? 6.348   -54.619 33.713  1.00 54.73  ? 396 LEU G N    1 
ATOM   10402 C  CA   . LEU G 1 189 ? 5.260   -55.578 33.393  1.00 54.41  ? 396 LEU G CA   1 
ATOM   10403 C  C    . LEU G 1 189 ? 5.324   -55.889 31.908  1.00 56.85  ? 396 LEU G C    1 
ATOM   10404 O  O    . LEU G 1 189 ? 5.334   -57.072 31.570  1.00 59.95  ? 396 LEU G O    1 
ATOM   10405 C  CB   . LEU G 1 189 ? 3.920   -54.946 33.765  1.00 50.10  ? 396 LEU G CB   1 
ATOM   10406 C  CG   . LEU G 1 189 ? 3.589   -54.949 35.252  1.00 60.27  ? 396 LEU G CG   1 
ATOM   10407 C  CD1  . LEU G 1 189 ? 2.285   -54.221 35.512  1.00 58.66  ? 396 LEU G CD1  1 
ATOM   10408 C  CD2  . LEU G 1 189 ? 3.521   -56.369 35.785  1.00 60.12  ? 396 LEU G CD2  1 
ATOM   10409 N  N    . THR G 1 190 ? 5.297   -54.863 31.070  1.00 50.15  ? 397 THR G N    1 
ATOM   10410 C  CA   . THR G 1 190 ? 5.462   -55.021 29.648  1.00 50.94  ? 397 THR G CA   1 
ATOM   10411 C  C    . THR G 1 190 ? 6.677   -54.221 29.213  1.00 61.33  ? 397 THR G C    1 
ATOM   10412 O  O    . THR G 1 190 ? 7.102   -53.271 29.884  1.00 61.80  ? 397 THR G O    1 
ATOM   10413 C  CB   . THR G 1 190 ? 4.223   -54.571 28.888  1.00 52.51  ? 397 THR G CB   1 
ATOM   10414 O  OG1  . THR G 1 190 ? 4.042   -53.153 29.041  1.00 55.49  ? 397 THR G OG1  1 
ATOM   10415 C  CG2  . THR G 1 190 ? 3.011   -55.312 29.444  1.00 51.88  ? 397 THR G CG2  1 
ATOM   10416 N  N    . LEU G 1 191 ? 7.261   -54.665 28.108  1.00 59.94  ? 398 LEU G N    1 
ATOM   10417 C  CA   . LEU G 1 191 ? 8.371   -54.014 27.465  1.00 52.81  ? 398 LEU G CA   1 
ATOM   10418 C  C    . LEU G 1 191 ? 7.939   -53.821 26.021  1.00 50.36  ? 398 LEU G C    1 
ATOM   10419 O  O    . LEU G 1 191 ? 7.444   -54.770 25.399  1.00 60.15  ? 398 LEU G O    1 
ATOM   10420 C  CB   . LEU G 1 191 ? 9.625   -54.858 27.572  1.00 53.02  ? 398 LEU G CB   1 
ATOM   10421 C  CG   . LEU G 1 191 ? 10.315  -54.586 28.897  1.00 58.38  ? 398 LEU G CG   1 
ATOM   10422 C  CD1  . LEU G 1 191 ? 11.268  -55.705 29.302  1.00 54.61  ? 398 LEU G CD1  1 
ATOM   10423 C  CD2  . LEU G 1 191 ? 11.039  -53.260 28.763  1.00 59.24  ? 398 LEU G CD2  1 
ATOM   10424 N  N    . PRO G 1 192 ? 8.056   -52.619 25.473  1.00 58.49  ? 399 PRO G N    1 
ATOM   10425 C  CA   . PRO G 1 192 ? 7.423   -52.319 24.172  1.00 63.55  ? 399 PRO G CA   1 
ATOM   10426 C  C    . PRO G 1 192 ? 8.200   -52.934 23.018  1.00 63.93  ? 399 PRO G C    1 
ATOM   10427 O  O    . PRO G 1 192 ? 9.361   -53.352 23.180  1.00 59.41  ? 399 PRO G O    1 
ATOM   10428 C  CB   . PRO G 1 192 ? 7.446   -50.778 24.117  1.00 59.15  ? 399 PRO G CB   1 
ATOM   10429 C  CG   . PRO G 1 192 ? 8.586   -50.390 24.969  1.00 59.11  ? 399 PRO G CG   1 
ATOM   10430 C  CD   . PRO G 1 192 ? 8.769   -51.461 26.030  1.00 57.38  ? 399 PRO G CD   1 
ATOM   10431 N  N    . PRO G 1 193 ? 7.590   -53.017 21.831  1.00 62.57  ? 400 PRO G N    1 
ATOM   10432 C  CA   . PRO G 1 193 ? 8.335   -53.556 20.677  1.00 61.23  ? 400 PRO G CA   1 
ATOM   10433 C  C    . PRO G 1 193 ? 9.616   -52.784 20.394  1.00 65.70  ? 400 PRO G C    1 
ATOM   10434 O  O    . PRO G 1 193 ? 10.685  -53.390 20.222  1.00 68.61  ? 400 PRO G O    1 
ATOM   10435 C  CB   . PRO G 1 193 ? 7.328   -53.437 19.521  1.00 65.51  ? 400 PRO G CB   1 
ATOM   10436 C  CG   . PRO G 1 193 ? 5.992   -53.137 20.147  1.00 63.48  ? 400 PRO G CG   1 
ATOM   10437 C  CD   . PRO G 1 193 ? 6.261   -52.496 21.459  1.00 64.70  ? 400 PRO G CD   1 
ATOM   10438 N  N    . VAL G 1 194 ? 9.521   -51.454 20.331  1.00 62.98  ? 401 VAL G N    1 
ATOM   10439 C  CA   . VAL G 1 194 ? 10.660  -50.557 20.176  1.00 61.95  ? 401 VAL G CA   1 
ATOM   10440 C  C    . VAL G 1 194 ? 10.974  -49.966 21.542  1.00 61.96  ? 401 VAL G C    1 
ATOM   10441 O  O    . VAL G 1 194 ? 10.103  -49.364 22.173  1.00 67.59  ? 401 VAL G O    1 
ATOM   10442 C  CB   . VAL G 1 194 ? 10.362  -49.438 19.166  1.00 63.18  ? 401 VAL G CB   1 
ATOM   10443 C  CG1  . VAL G 1 194 ? 11.543  -48.451 19.111  1.00 64.32  ? 401 VAL G CG1  1 
ATOM   10444 C  CG2  . VAL G 1 194 ? 10.064  -50.009 17.792  1.00 65.11  ? 401 VAL G CG2  1 
ATOM   10445 N  N    . LEU G 1 195 ? 12.185  -50.202 22.037  1.00 57.49  ? 402 LEU G N    1 
ATOM   10446 C  CA   . LEU G 1 195 ? 12.546  -49.732 23.398  1.00 64.38  ? 402 LEU G CA   1 
ATOM   10447 C  C    . LEU G 1 195 ? 13.583  -48.609 23.332  1.00 65.69  ? 402 LEU G C    1 
ATOM   10448 O  O    . LEU G 1 195 ? 14.694  -48.855 22.854  1.00 63.27  ? 402 LEU G O    1 
ATOM   10449 C  CB   . LEU G 1 195 ? 13.075  -50.915 24.208  1.00 57.23  ? 402 LEU G CB   1 
ATOM   10450 C  CG   . LEU G 1 195 ? 13.469  -50.605 25.647  1.00 62.42  ? 402 LEU G CG   1 
ATOM   10451 C  CD1  . LEU G 1 195 ? 12.268  -50.148 26.451  1.00 64.30  ? 402 LEU G CD1  1 
ATOM   10452 C  CD2  . LEU G 1 195 ? 14.103  -51.819 26.292  1.00 61.38  ? 402 LEU G CD2  1 
ATOM   10453 N  N    . HIS G 1 196 ? 13.219  -47.421 23.808  1.00 64.60  ? 403 HIS G N    1 
ATOM   10454 C  CA   . HIS G 1 196 ? 14.191  -46.306 23.885  1.00 59.06  ? 403 HIS G CA   1 
ATOM   10455 C  C    . HIS G 1 196 ? 14.906  -46.389 25.232  1.00 59.14  ? 403 HIS G C    1 
ATOM   10456 O  O    . HIS G 1 196 ? 14.238  -46.653 26.234  1.00 62.78  ? 403 HIS G O    1 
ATOM   10457 C  CB   . HIS G 1 196 ? 13.480  -44.973 23.703  1.00 57.46  ? 403 HIS G CB   1 
ATOM   10458 C  CG   . HIS G 1 196 ? 13.006  -44.692 22.321  1.00 59.87  ? 403 HIS G CG   1 
ATOM   10459 N  ND1  . HIS G 1 196 ? 13.403  -45.435 21.234  1.00 61.09  ? 403 HIS G ND1  1 
ATOM   10460 C  CD2  . HIS G 1 196 ? 12.176  -43.741 21.848  1.00 58.63  ? 403 HIS G CD2  1 
ATOM   10461 C  CE1  . HIS G 1 196 ? 12.840  -44.953 20.149  1.00 62.89  ? 403 HIS G CE1  1 
ATOM   10462 N  NE2  . HIS G 1 196 ? 12.084  -43.914 20.499  1.00 65.48  ? 403 HIS G NE2  1 
ATOM   10463 N  N    . LEU G 1 197 ? 16.221  -46.209 25.237  1.00 54.74  ? 404 LEU G N    1 
ATOM   10464 C  CA   . LEU G 1 197 ? 17.006  -46.295 26.488  1.00 58.82  ? 404 LEU G CA   1 
ATOM   10465 C  C    . LEU G 1 197 ? 17.881  -45.045 26.625  1.00 64.73  ? 404 LEU G C    1 
ATOM   10466 O  O    . LEU G 1 197 ? 18.718  -44.826 25.748  1.00 60.08  ? 404 LEU G O    1 
ATOM   10467 C  CB   . LEU G 1 197 ? 17.852  -47.568 26.440  1.00 62.11  ? 404 LEU G CB   1 
ATOM   10468 C  CG   . LEU G 1 197 ? 17.081  -48.882 26.517  1.00 68.61  ? 404 LEU G CG   1 
ATOM   10469 C  CD1  . LEU G 1 197 ? 18.023  -50.062 26.409  1.00 63.98  ? 404 LEU G CD1  1 
ATOM   10470 C  CD2  . LEU G 1 197 ? 16.292  -48.969 27.807  1.00 61.10  ? 404 LEU G CD2  1 
ATOM   10471 N  N    . GLN G 1 198 ? 17.678  -44.256 27.685  1.00 58.31  ? 405 GLN G N    1 
ATOM   10472 C  CA   . GLN G 1 198 ? 18.507  -43.050 27.940  1.00 59.05  ? 405 GLN G CA   1 
ATOM   10473 C  C    . GLN G 1 198 ? 19.578  -43.382 28.973  1.00 63.73  ? 405 GLN G C    1 
ATOM   10474 O  O    . GLN G 1 198 ? 19.223  -43.789 30.088  1.00 58.56  ? 405 GLN G O    1 
ATOM   10475 C  CB   . GLN G 1 198 ? 17.662  -41.876 28.422  1.00 53.86  ? 405 GLN G CB   1 
ATOM   10476 C  CG   . GLN G 1 198 ? 18.476  -40.637 28.762  1.00 58.86  ? 405 GLN G CG   1 
ATOM   10477 C  CD   . GLN G 1 198 ? 17.629  -39.511 29.297  1.00 61.90  ? 405 GLN G CD   1 
ATOM   10478 O  OE1  . GLN G 1 198 ? 16.484  -39.699 29.691  1.00 64.35  ? 405 GLN G OE1  1 
ATOM   10479 N  NE2  . GLN G 1 198 ? 18.189  -38.316 29.301  1.00 57.43  ? 405 GLN G NE2  1 
ATOM   10480 N  N    . LEU G 1 199 ? 20.843  -43.208 28.600  1.00 61.50  ? 406 LEU G N    1 
ATOM   10481 C  CA   . LEU G 1 199 ? 21.951  -43.514 29.502  1.00 64.23  ? 406 LEU G CA   1 
ATOM   10482 C  C    . LEU G 1 199 ? 22.222  -42.275 30.344  1.00 63.32  ? 406 LEU G C    1 
ATOM   10483 O  O    . LEU G 1 199 ? 22.455  -41.192 29.794  1.00 67.41  ? 406 LEU G O    1 
ATOM   10484 N  N    . MET G 1 200 ? 22.191  -42.425 31.670  1.00 56.86  ? 407 MET G N    1 
ATOM   10485 C  CA   . MET G 1 200 ? 22.325  -41.276 32.569  1.00 64.68  ? 407 MET G CA   1 
ATOM   10486 C  C    . MET G 1 200 ? 23.786  -40.815 32.638  1.00 66.43  ? 407 MET G C    1 
ATOM   10487 O  O    . MET G 1 200 ? 24.494  -41.004 33.628  1.00 66.57  ? 407 MET G O    1 
ATOM   10488 C  CB   . MET G 1 200 ? 21.793  -41.621 33.949  1.00 61.94  ? 407 MET G CB   1 
ATOM   10489 C  CG   . MET G 1 200 ? 20.356  -42.056 33.948  1.00 67.47  ? 407 MET G CG   1 
ATOM   10490 S  SD   . MET G 1 200 ? 19.214  -40.689 33.890  1.00 73.74  ? 407 MET G SD   1 
ATOM   10491 C  CE   . MET G 1 200 ? 19.027  -40.516 35.662  1.00 68.36  ? 407 MET G CE   1 
ATOM   10492 N  N    . ARG G 1 201 ? 24.242  -40.167 31.566  1.00 64.44  ? 408 ARG G N    1 
ATOM   10493 C  CA   . ARG G 1 201 ? 25.664  -39.749 31.469  1.00 66.58  ? 408 ARG G CA   1 
ATOM   10494 C  C    . ARG G 1 201 ? 25.830  -38.314 31.970  1.00 64.27  ? 408 ARG G C    1 
ATOM   10495 O  O    . ARG G 1 201 ? 26.416  -37.501 31.248  1.00 65.19  ? 408 ARG G O    1 
ATOM   10496 C  CB   . ARG G 1 201 ? 26.109  -39.889 30.015  1.00 58.98  ? 408 ARG G CB   1 
ATOM   10497 C  CG   . ARG G 1 201 ? 26.272  -41.322 29.540  1.00 63.79  ? 408 ARG G CG   1 
ATOM   10498 C  CD   . ARG G 1 201 ? 27.305  -41.298 28.437  1.00 70.01  ? 408 ARG G CD   1 
ATOM   10499 N  NE   . ARG G 1 201 ? 27.805  -42.606 28.046  1.00 66.15  ? 408 ARG G NE   1 
ATOM   10500 C  CZ   . ARG G 1 201 ? 28.837  -43.223 28.603  1.00 70.34  ? 408 ARG G CZ   1 
ATOM   10501 N  NH1  . ARG G 1 201 ? 29.494  -42.659 29.600  1.00 68.61  ? 408 ARG G NH1  1 
ATOM   10502 N  NH2  . ARG G 1 201 ? 29.212  -44.405 28.156  1.00 73.99  ? 408 ARG G NH2  1 
ATOM   10503 N  N    . PHE G 1 202 ? 25.334  -38.038 33.171  1.00 65.46  ? 409 PHE G N    1 
ATOM   10504 C  CA   . PHE G 1 202 ? 25.430  -36.677 33.746  1.00 66.20  ? 409 PHE G CA   1 
ATOM   10505 C  C    . PHE G 1 202 ? 25.415  -36.715 35.277  1.00 65.61  ? 409 PHE G C    1 
ATOM   10506 O  O    . PHE G 1 202 ? 24.899  -37.678 35.862  1.00 63.81  ? 409 PHE G O    1 
ATOM   10507 C  CB   . PHE G 1 202 ? 24.334  -35.759 33.200  1.00 64.85  ? 409 PHE G CB   1 
ATOM   10508 C  CG   . PHE G 1 202 ? 23.055  -36.391 32.714  1.00 65.04  ? 409 PHE G CG   1 
ATOM   10509 C  CD1  . PHE G 1 202 ? 22.210  -37.061 33.582  1.00 69.11  ? 409 PHE G CD1  1 
ATOM   10510 C  CD2  . PHE G 1 202 ? 22.670  -36.259 31.392  1.00 59.23  ? 409 PHE G CD2  1 
ATOM   10511 C  CE1  . PHE G 1 202 ? 21.026  -37.617 33.126  1.00 69.61  ? 409 PHE G CE1  1 
ATOM   10512 C  CE2  . PHE G 1 202 ? 21.484  -36.812 30.940  1.00 56.32  ? 409 PHE G CE2  1 
ATOM   10513 C  CZ   . PHE G 1 202 ? 20.667  -37.493 31.807  1.00 59.09  ? 409 PHE G CZ   1 
ATOM   10514 N  N    . MET G 1 203 ? 25.978  -35.679 35.897  1.00 70.37  ? 410 MET G N    1 
ATOM   10515 C  CA   . MET G 1 203 ? 26.018  -35.569 37.375  1.00 76.57  ? 410 MET G CA   1 
ATOM   10516 C  C    . MET G 1 203 ? 26.186  -34.089 37.730  1.00 86.18  ? 410 MET G C    1 
ATOM   10517 O  O    . MET G 1 203 ? 27.160  -33.482 37.271  1.00 83.05  ? 410 MET G O    1 
ATOM   10518 C  CB   . MET G 1 203 ? 27.200  -36.349 37.951  1.00 71.98  ? 410 MET G CB   1 
ATOM   10519 N  N    . TYR G 1 204 ? 25.261  -33.538 38.515  1.00 88.77  ? 411 TYR G N    1 
ATOM   10520 C  CA   . TYR G 1 204 ? 25.373  -32.120 38.935  1.00 85.29  ? 411 TYR G CA   1 
ATOM   10521 C  C    . TYR G 1 204 ? 26.429  -31.999 40.033  1.00 91.42  ? 411 TYR G C    1 
ATOM   10522 O  O    . TYR G 1 204 ? 26.490  -32.868 40.923  1.00 87.77  ? 411 TYR G O    1 
ATOM   10523 C  CB   . TYR G 1 204 ? 24.029  -31.531 39.361  1.00 78.14  ? 411 TYR G CB   1 
ATOM   10524 C  CG   . TYR G 1 204 ? 24.134  -30.130 39.907  1.00 84.42  ? 411 TYR G CG   1 
ATOM   10525 C  CD1  . TYR G 1 204 ? 24.511  -29.077 39.092  1.00 89.53  ? 411 TYR G CD1  1 
ATOM   10526 C  CD2  . TYR G 1 204 ? 23.905  -29.861 41.245  1.00 83.68  ? 411 TYR G CD2  1 
ATOM   10527 C  CE1  . TYR G 1 204 ? 24.647  -27.792 39.586  1.00 87.71  ? 411 TYR G CE1  1 
ATOM   10528 C  CE2  . TYR G 1 204 ? 24.029  -28.580 41.755  1.00 83.28  ? 411 TYR G CE2  1 
ATOM   10529 C  CZ   . TYR G 1 204 ? 24.403  -27.542 40.923  1.00 85.05  ? 411 TYR G CZ   1 
ATOM   10530 O  OH   . TYR G 1 204 ? 24.521  -26.276 41.413  1.00 91.80  ? 411 TYR G OH   1 
ATOM   10531 N  N    . ASP G 1 205 ? 27.230  -30.927 39.944  1.00 90.91  ? 412 ASP G N    1 
ATOM   10532 C  CA   . ASP G 1 205 ? 28.337  -30.693 40.906  1.00 99.38  ? 412 ASP G CA   1 
ATOM   10533 C  C    . ASP G 1 205 ? 28.169  -29.364 41.654  1.00 98.32  ? 412 ASP G C    1 
ATOM   10534 O  O    . ASP G 1 205 ? 28.375  -28.298 41.037  1.00 92.03  ? 412 ASP G O    1 
ATOM   10535 N  N    . PRO G 1 206 ? 27.778  -29.390 42.943  1.00 95.61  ? 413 PRO G N    1 
ATOM   10536 C  CA   . PRO G 1 206 ? 27.681  -28.199 43.802  1.00 98.17  ? 413 PRO G CA   1 
ATOM   10537 C  C    . PRO G 1 206 ? 29.047  -27.708 44.300  1.00 94.54  ? 413 PRO G C    1 
ATOM   10538 O  O    . PRO G 1 206 ? 29.541  -26.674 43.839  1.00 91.92  ? 413 PRO G O    1 
ATOM   10539 C  CB   . PRO G 1 206 ? 26.812  -28.680 44.978  1.00 94.36  ? 413 PRO G CB   1 
ATOM   10540 C  CG   . PRO G 1 206 ? 26.278  -30.046 44.567  1.00 92.40  ? 413 PRO G CG   1 
ATOM   10541 C  CD   . PRO G 1 206 ? 27.300  -30.599 43.631  1.00 87.17  ? 413 PRO G CD   1 
ATOM   10542 N  N    . ASN G 1 211 ? 27.510  -29.204 37.103  1.00 89.97  ? 418 ASN G N    1 
ATOM   10543 C  CA   . ASN G 1 211 ? 26.901  -30.150 36.130  1.00 88.20  ? 418 ASN G CA   1 
ATOM   10544 C  C    . ASN G 1 211 ? 27.969  -30.615 35.140  1.00 87.33  ? 418 ASN G C    1 
ATOM   10545 O  O    . ASN G 1 211 ? 28.419  -29.796 34.320  1.00 89.43  ? 418 ASN G O    1 
ATOM   10546 C  CB   . ASN G 1 211 ? 25.709  -29.538 35.398  1.00 80.38  ? 418 ASN G CB   1 
ATOM   10547 N  N    . ILE G 1 212 ? 28.353  -31.886 35.222  1.00 85.11  ? 419 ILE G N    1 
ATOM   10548 C  CA   . ILE G 1 212 ? 29.405  -32.442 34.322  1.00 84.33  ? 419 ILE G CA   1 
ATOM   10549 C  C    . ILE G 1 212 ? 28.873  -33.683 33.609  1.00 77.19  ? 419 ILE G C    1 
ATOM   10550 O  O    . ILE G 1 212 ? 28.000  -34.360 34.163  1.00 68.68  ? 419 ILE G O    1 
ATOM   10551 C  CB   . ILE G 1 212 ? 30.691  -32.772 35.106  1.00 79.92  ? 419 ILE G CB   1 
ATOM   10552 C  CG1  . ILE G 1 212 ? 30.404  -33.573 36.379  1.00 76.71  ? 419 ILE G CG1  1 
ATOM   10553 C  CG2  . ILE G 1 212 ? 31.484  -31.510 35.401  1.00 84.00  ? 419 ILE G CG2  1 
ATOM   10554 C  CD1  . ILE G 1 212 ? 31.638  -34.124 37.047  1.00 73.71  ? 419 ILE G CD1  1 
ATOM   10555 N  N    . LYS G 1 213 ? 29.383  -33.946 32.410  1.00 76.11  ? 420 LYS G N    1 
ATOM   10556 C  CA   . LYS G 1 213 ? 28.999  -35.125 31.636  1.00 69.30  ? 420 LYS G CA   1 
ATOM   10557 C  C    . LYS G 1 213 ? 29.833  -36.330 32.055  1.00 69.81  ? 420 LYS G C    1 
ATOM   10558 O  O    . LYS G 1 213 ? 31.066  -36.268 32.056  1.00 71.18  ? 420 LYS G O    1 
ATOM   10559 C  CB   . LYS G 1 213 ? 29.175  -34.892 30.139  1.00 58.94  ? 420 LYS G CB   1 
ATOM   10560 C  CG   . LYS G 1 213 ? 29.398  -36.177 29.410  1.00 59.46  ? 420 LYS G CG   1 
ATOM   10561 C  CD   . LYS G 1 213 ? 29.485  -35.994 27.937  1.00 68.82  ? 420 LYS G CD   1 
ATOM   10562 C  CE   . LYS G 1 213 ? 29.260  -37.327 27.271  1.00 69.27  ? 420 LYS G CE   1 
ATOM   10563 N  NZ   . LYS G 1 213 ? 29.165  -37.181 25.808  1.00 70.11  ? 420 LYS G NZ   1 
ATOM   10564 N  N    . ILE G 1 214 ? 29.155  -37.430 32.379  1.00 71.87  ? 421 ILE G N    1 
ATOM   10565 C  CA   . ILE G 1 214 ? 29.801  -38.675 32.792  1.00 67.10  ? 421 ILE G CA   1 
ATOM   10566 C  C    . ILE G 1 214 ? 30.281  -39.433 31.557  1.00 73.72  ? 421 ILE G C    1 
ATOM   10567 O  O    . ILE G 1 214 ? 29.466  -39.880 30.739  1.00 73.08  ? 421 ILE G O    1 
ATOM   10568 C  CB   . ILE G 1 214 ? 28.835  -39.537 33.611  1.00 62.77  ? 421 ILE G CB   1 
ATOM   10569 C  CG1  . ILE G 1 214 ? 28.528  -38.859 34.950  1.00 65.81  ? 421 ILE G CG1  1 
ATOM   10570 C  CG2  . ILE G 1 214 ? 29.414  -40.922 33.799  1.00 65.92  ? 421 ILE G CG2  1 
ATOM   10571 C  CD1  . ILE G 1 214 ? 27.863  -39.757 35.983  1.00 63.49  ? 421 ILE G CD1  1 
ATOM   10572 N  N    . ASN G 1 215 ? 31.602  -39.618 31.438  1.00 73.57  ? 422 ASN G N    1 
ATOM   10573 C  CA   . ASN G 1 215 ? 32.200  -40.224 30.247  1.00 74.79  ? 422 ASN G CA   1 
ATOM   10574 C  C    . ASN G 1 215 ? 32.672  -41.667 30.455  1.00 71.33  ? 422 ASN G C    1 
ATOM   10575 O  O    . ASN G 1 215 ? 33.320  -42.225 29.562  1.00 64.74  ? 422 ASN G O    1 
ATOM   10576 C  CB   . ASN G 1 215 ? 33.369  -39.361 29.746  1.00 75.37  ? 422 ASN G CB   1 
ATOM   10577 C  CG   . ASN G 1 215 ? 32.908  -38.103 29.008  1.00 74.76  ? 422 ASN G CG   1 
ATOM   10578 O  OD1  . ASN G 1 215 ? 32.275  -38.181 27.955  1.00 72.11  ? 422 ASN G OD1  1 
ATOM   10579 N  ND2  . ASN G 1 215 ? 33.239  -36.936 29.559  1.00 76.35  ? 422 ASN G ND2  1 
ATOM   10580 N  N    . ASP G 1 216 ? 32.352  -42.290 31.591  1.00 68.19  ? 423 ASP G N    1 
ATOM   10581 C  CA   . ASP G 1 216 ? 32.907  -43.594 31.930  1.00 63.61  ? 423 ASP G CA   1 
ATOM   10582 C  C    . ASP G 1 216 ? 32.608  -44.638 30.856  1.00 69.52  ? 423 ASP G C    1 
ATOM   10583 O  O    . ASP G 1 216 ? 31.754  -44.463 29.981  1.00 68.43  ? 423 ASP G O    1 
ATOM   10584 C  CB   . ASP G 1 216 ? 32.349  -44.099 33.254  1.00 64.73  ? 423 ASP G CB   1 
ATOM   10585 C  CG   . ASP G 1 216 ? 32.593  -43.150 34.383  1.00 69.57  ? 423 ASP G CG   1 
ATOM   10586 O  OD1  . ASP G 1 216 ? 33.322  -42.162 34.170  1.00 71.32  ? 423 ASP G OD1  1 
ATOM   10587 O  OD2  . ASP G 1 216 ? 32.046  -43.389 35.483  1.00 73.01  ? 423 ASP G OD2  1 
ATOM   10588 N  N    . ARG G 1 217 ? 33.328  -45.755 30.949  1.00 69.34  ? 424 ARG G N    1 
ATOM   10589 C  CA   . ARG G 1 217 ? 33.104  -46.868 30.034  1.00 76.21  ? 424 ARG G CA   1 
ATOM   10590 C  C    . ARG G 1 217 ? 31.771  -47.530 30.363  1.00 69.47  ? 424 ARG G C    1 
ATOM   10591 O  O    . ARG G 1 217 ? 31.542  -47.955 31.502  1.00 67.30  ? 424 ARG G O    1 
ATOM   10592 N  N    . PHE G 1 218 ? 30.885  -47.620 29.377  1.00 69.51  ? 425 PHE G N    1 
ATOM   10593 C  CA   . PHE G 1 218 ? 29.609  -48.303 29.576  1.00 74.46  ? 425 PHE G CA   1 
ATOM   10594 C  C    . PHE G 1 218 ? 29.363  -49.277 28.433  1.00 69.84  ? 425 PHE G C    1 
ATOM   10595 O  O    . PHE G 1 218 ? 29.232  -48.865 27.270  1.00 72.36  ? 425 PHE G O    1 
ATOM   10596 C  CB   . PHE G 1 218 ? 28.449  -47.309 29.704  1.00 72.20  ? 425 PHE G CB   1 
ATOM   10597 C  CG   . PHE G 1 218 ? 27.225  -47.916 30.304  1.00 68.95  ? 425 PHE G CG   1 
ATOM   10598 C  CD1  . PHE G 1 218 ? 27.172  -48.183 31.669  1.00 67.86  ? 425 PHE G CD1  1 
ATOM   10599 C  CD2  . PHE G 1 218 ? 26.143  -48.264 29.496  1.00 58.85  ? 425 PHE G CD2  1 
ATOM   10600 C  CE1  . PHE G 1 218 ? 26.045  -48.773 32.232  1.00 70.60  ? 425 PHE G CE1  1 
ATOM   10601 C  CE2  . PHE G 1 218 ? 25.025  -48.843 30.030  1.00 63.82  ? 425 PHE G CE2  1 
ATOM   10602 C  CZ   . PHE G 1 218 ? 24.969  -49.102 31.414  1.00 74.60  ? 425 PHE G CZ   1 
ATOM   10603 N  N    . GLU G 1 219 ? 29.280  -50.562 28.772  1.00 69.83  ? 426 GLU G N    1 
ATOM   10604 C  CA   . GLU G 1 219 ? 29.225  -51.633 27.787  1.00 74.50  ? 426 GLU G CA   1 
ATOM   10605 C  C    . GLU G 1 219 ? 27.784  -52.032 27.504  1.00 69.41  ? 426 GLU G C    1 
ATOM   10606 O  O    . GLU G 1 219 ? 26.963  -52.133 28.418  1.00 70.24  ? 426 GLU G O    1 
ATOM   10607 N  N    . PHE G 1 220 ? 27.486  -52.279 26.232  1.00 66.75  ? 427 PHE G N    1 
ATOM   10608 C  CA   . PHE G 1 220 ? 26.147  -52.718 25.857  1.00 74.22  ? 427 PHE G CA   1 
ATOM   10609 C  C    . PHE G 1 220 ? 26.218  -53.663 24.666  1.00 72.49  ? 427 PHE G C    1 
ATOM   10610 O  O    . PHE G 1 220 ? 27.040  -53.445 23.765  1.00 75.46  ? 427 PHE G O    1 
ATOM   10611 C  CB   . PHE G 1 220 ? 25.247  -51.525 25.529  1.00 70.06  ? 427 PHE G CB   1 
ATOM   10612 C  CG   . PHE G 1 220 ? 25.849  -50.570 24.552  1.00 69.29  ? 427 PHE G CG   1 
ATOM   10613 C  CD1  . PHE G 1 220 ? 26.720  -49.569 24.981  1.00 71.69  ? 427 PHE G CD1  1 
ATOM   10614 C  CD2  . PHE G 1 220 ? 25.540  -50.663 23.201  1.00 70.31  ? 427 PHE G CD2  1 
ATOM   10615 C  CE1  . PHE G 1 220 ? 27.283  -48.675 24.069  1.00 72.96  ? 427 PHE G CE1  1 
ATOM   10616 C  CE2  . PHE G 1 220 ? 26.092  -49.781 22.282  1.00 77.92  ? 427 PHE G CE2  1 
ATOM   10617 C  CZ   . PHE G 1 220 ? 26.969  -48.779 22.716  1.00 76.82  ? 427 PHE G CZ   1 
ATOM   10618 N  N    . PRO G 1 221 ? 25.382  -54.716 24.624  1.00 77.97  ? 428 PRO G N    1 
ATOM   10619 C  CA   . PRO G 1 221 ? 25.548  -55.741 23.584  1.00 79.65  ? 428 PRO G CA   1 
ATOM   10620 C  C    . PRO G 1 221 ? 24.570  -55.613 22.428  1.00 75.75  ? 428 PRO G C    1 
ATOM   10621 O  O    . PRO G 1 221 ? 23.571  -54.883 22.496  1.00 72.37  ? 428 PRO G O    1 
ATOM   10622 C  CB   . PRO G 1 221 ? 25.306  -57.038 24.358  1.00 76.20  ? 428 PRO G CB   1 
ATOM   10623 C  CG   . PRO G 1 221 ? 24.201  -56.627 25.345  1.00 73.96  ? 428 PRO G CG   1 
ATOM   10624 C  CD   . PRO G 1 221 ? 24.359  -55.127 25.602  1.00 73.18  ? 428 PRO G CD   1 
ATOM   10625 N  N    . GLU G 1 222 ? 24.868  -56.337 21.348  1.00 78.49  ? 429 GLU G N    1 
ATOM   10626 C  CA   . GLU G 1 222 ? 23.909  -56.443 20.257  1.00 74.78  ? 429 GLU G CA   1 
ATOM   10627 C  C    . GLU G 1 222 ? 22.677  -57.228 20.688  1.00 68.87  ? 429 GLU G C    1 
ATOM   10628 O  O    . GLU G 1 222 ? 21.585  -57.002 20.158  1.00 73.53  ? 429 GLU G O    1 
ATOM   10629 C  CB   . GLU G 1 222 ? 24.572  -57.082 19.035  1.00 63.60  ? 429 GLU G CB   1 
ATOM   10630 N  N    . GLN G 1 223 ? 22.820  -58.114 21.672  1.00 70.43  ? 430 GLN G N    1 
ATOM   10631 C  CA   . GLN G 1 223 ? 21.751  -59.009 22.106  1.00 71.85  ? 430 GLN G CA   1 
ATOM   10632 C  C    . GLN G 1 223 ? 21.420  -58.689 23.558  1.00 76.88  ? 430 GLN G C    1 
ATOM   10633 O  O    . GLN G 1 223 ? 22.223  -58.963 24.464  1.00 74.64  ? 430 GLN G O    1 
ATOM   10634 N  N    . LEU G 1 224 ? 20.235  -58.116 23.781  1.00 77.89  ? 431 LEU G N    1 
ATOM   10635 C  CA   . LEU G 1 224 ? 19.836  -57.719 25.124  1.00 70.12  ? 431 LEU G CA   1 
ATOM   10636 C  C    . LEU G 1 224 ? 18.671  -58.573 25.596  1.00 72.65  ? 431 LEU G C    1 
ATOM   10637 O  O    . LEU G 1 224 ? 17.539  -58.414 25.103  1.00 71.78  ? 431 LEU G O    1 
ATOM   10638 C  CB   . LEU G 1 224 ? 19.465  -56.241 25.168  1.00 72.11  ? 431 LEU G CB   1 
ATOM   10639 C  CG   . LEU G 1 224 ? 19.159  -55.734 26.576  1.00 73.24  ? 431 LEU G CG   1 
ATOM   10640 C  CD1  . LEU G 1 224 ? 20.287  -56.037 27.586  1.00 73.96  ? 431 LEU G CD1  1 
ATOM   10641 C  CD2  . LEU G 1 224 ? 18.864  -54.253 26.513  1.00 70.19  ? 431 LEU G CD2  1 
ATOM   10642 N  N    . PRO G 1 225 ? 18.909  -59.489 26.521  1.00 75.73  ? 432 PRO G N    1 
ATOM   10643 C  CA   . PRO G 1 225 ? 17.823  -60.305 27.073  1.00 71.89  ? 432 PRO G CA   1 
ATOM   10644 C  C    . PRO G 1 225 ? 17.259  -59.715 28.353  1.00 69.87  ? 432 PRO G C    1 
ATOM   10645 O  O    . PRO G 1 225 ? 17.894  -59.750 29.416  1.00 68.97  ? 432 PRO G O    1 
ATOM   10646 C  CB   . PRO G 1 225 ? 18.508  -61.653 27.323  1.00 74.76  ? 432 PRO G CB   1 
ATOM   10647 C  CG   . PRO G 1 225 ? 19.931  -61.292 27.604  1.00 68.30  ? 432 PRO G CG   1 
ATOM   10648 C  CD   . PRO G 1 225 ? 20.240  -60.009 26.876  1.00 71.78  ? 432 PRO G CD   1 
ATOM   10649 N  N    . LEU G 1 226 ? 16.042  -59.195 28.267  1.00 70.35  ? 433 LEU G N    1 
ATOM   10650 C  CA   . LEU G 1 226 ? 15.472  -58.438 29.367  1.00 67.44  ? 433 LEU G CA   1 
ATOM   10651 C  C    . LEU G 1 226 ? 14.528  -59.247 30.252  1.00 72.05  ? 433 LEU G C    1 
ATOM   10652 O  O    . LEU G 1 226 ? 14.098  -58.725 31.289  1.00 73.78  ? 433 LEU G O    1 
ATOM   10653 C  CB   . LEU G 1 226 ? 14.751  -57.209 28.809  1.00 65.70  ? 433 LEU G CB   1 
ATOM   10654 C  CG   . LEU G 1 226 ? 15.727  -56.249 28.123  1.00 60.48  ? 433 LEU G CG   1 
ATOM   10655 C  CD1  . LEU G 1 226 ? 15.010  -55.063 27.537  1.00 59.02  ? 433 LEU G CD1  1 
ATOM   10656 C  CD2  . LEU G 1 226 ? 16.776  -55.785 29.111  1.00 67.99  ? 433 LEU G CD2  1 
ATOM   10657 N  N    . ASP G 1 227 ? 14.231  -60.508 29.889  1.00 67.70  ? 434 ASP G N    1 
ATOM   10658 C  CA   . ASP G 1 227 ? 13.267  -61.332 30.623  1.00 63.51  ? 434 ASP G CA   1 
ATOM   10659 C  C    . ASP G 1 227 ? 13.479  -61.276 32.132  1.00 65.57  ? 434 ASP G C    1 
ATOM   10660 O  O    . ASP G 1 227 ? 12.510  -61.232 32.902  1.00 60.43  ? 434 ASP G O    1 
ATOM   10661 C  CB   . ASP G 1 227 ? 13.338  -62.787 30.140  1.00 62.68  ? 434 ASP G CB   1 
ATOM   10662 C  CG   . ASP G 1 227 ? 12.158  -63.167 29.243  1.00 66.20  ? 434 ASP G CG   1 
ATOM   10663 O  OD1  . ASP G 1 227 ? 11.095  -62.533 29.358  1.00 70.37  ? 434 ASP G OD1  1 
ATOM   10664 O  OD2  . ASP G 1 227 ? 12.281  -64.088 28.411  1.00 72.65  ? 434 ASP G OD2  1 
ATOM   10665 N  N    . GLU G 1 228 ? 14.738  -61.272 32.577  1.00 66.93  ? 435 GLU G N    1 
ATOM   10666 C  CA   . GLU G 1 228 ? 15.019  -61.308 34.009  1.00 69.02  ? 435 GLU G CA   1 
ATOM   10667 C  C    . GLU G 1 228 ? 14.360  -60.156 34.766  1.00 69.04  ? 435 GLU G C    1 
ATOM   10668 O  O    . GLU G 1 228 ? 14.149  -60.262 35.982  1.00 63.36  ? 435 GLU G O    1 
ATOM   10669 C  CB   . GLU G 1 228 ? 16.530  -61.292 34.229  1.00 71.90  ? 435 GLU G CB   1 
ATOM   10670 C  CG   . GLU G 1 228 ? 17.004  -62.258 35.293  1.00 77.37  ? 435 GLU G CG   1 
ATOM   10671 C  CD   . GLU G 1 228 ? 16.954  -61.650 36.661  1.00 78.17  ? 435 GLU G CD   1 
ATOM   10672 O  OE1  . GLU G 1 228 ? 17.657  -60.641 36.881  1.00 82.30  ? 435 GLU G OE1  1 
ATOM   10673 O  OE2  . GLU G 1 228 ? 16.205  -62.175 37.508  1.00 88.68  ? 435 GLU G OE2  1 
ATOM   10674 N  N    . PHE G 1 229 ? 14.003  -59.078 34.069  1.00 63.68  ? 436 PHE G N    1 
ATOM   10675 C  CA   . PHE G 1 229 ? 13.487  -57.868 34.688  1.00 65.27  ? 436 PHE G CA   1 
ATOM   10676 C  C    . PHE G 1 229 ? 11.985  -57.704 34.496  1.00 64.97  ? 436 PHE G C    1 
ATOM   10677 O  O    . PHE G 1 229 ? 11.409  -56.702 34.940  1.00 61.18  ? 436 PHE G O    1 
ATOM   10678 C  CB   . PHE G 1 229 ? 14.260  -56.664 34.139  1.00 66.32  ? 436 PHE G CB   1 
ATOM   10679 C  CG   . PHE G 1 229 ? 15.746  -56.903 34.073  1.00 65.94  ? 436 PHE G CG   1 
ATOM   10680 C  CD1  . PHE G 1 229 ? 16.504  -56.965 35.239  1.00 60.98  ? 436 PHE G CD1  1 
ATOM   10681 C  CD2  . PHE G 1 229 ? 16.370  -57.126 32.857  1.00 63.46  ? 436 PHE G CD2  1 
ATOM   10682 C  CE1  . PHE G 1 229 ? 17.857  -57.209 35.187  1.00 64.28  ? 436 PHE G CE1  1 
ATOM   10683 C  CE2  . PHE G 1 229 ? 17.718  -57.377 32.796  1.00 60.61  ? 436 PHE G CE2  1 
ATOM   10684 C  CZ   . PHE G 1 229 ? 18.467  -57.415 33.964  1.00 64.91  ? 436 PHE G CZ   1 
ATOM   10685 N  N    . LEU G 1 230 ? 11.344  -58.660 33.836  1.00 62.63  ? 437 LEU G N    1 
ATOM   10686 C  CA   . LEU G 1 230 ? 9.900   -58.748 33.843  1.00 59.92  ? 437 LEU G CA   1 
ATOM   10687 C  C    . LEU G 1 230 ? 9.447   -59.376 35.148  1.00 60.24  ? 437 LEU G C    1 
ATOM   10688 O  O    . LEU G 1 230 ? 10.188  -60.128 35.787  1.00 61.34  ? 437 LEU G O    1 
ATOM   10689 C  CB   . LEU G 1 230 ? 9.399   -59.573 32.662  1.00 60.95  ? 437 LEU G CB   1 
ATOM   10690 C  CG   . LEU G 1 230 ? 9.555   -58.913 31.302  1.00 63.43  ? 437 LEU G CG   1 
ATOM   10691 C  CD1  . LEU G 1 230 ? 9.310   -59.912 30.184  1.00 61.23  ? 437 LEU G CD1  1 
ATOM   10692 C  CD2  . LEU G 1 230 ? 8.592   -57.733 31.201  1.00 59.39  ? 437 LEU G CD2  1 
ATOM   10693 N  N    . GLN G 1 231 ? 8.227   -59.026 35.556  1.00 58.86  ? 438 GLN G N    1 
ATOM   10694 C  CA   . GLN G 1 231 ? 7.613   -59.632 36.734  1.00 60.43  ? 438 GLN G CA   1 
ATOM   10695 C  C    . GLN G 1 231 ? 7.048   -61.007 36.413  1.00 65.19  ? 438 GLN G C    1 
ATOM   10696 O  O    . GLN G 1 231 ? 7.062   -61.910 37.262  1.00 58.44  ? 438 GLN G O    1 
ATOM   10697 C  CB   . GLN G 1 231 ? 6.506   -58.724 37.262  1.00 54.24  ? 438 GLN G CB   1 
ATOM   10698 C  CG   . GLN G 1 231 ? 6.046   -59.094 38.621  1.00 58.52  ? 438 GLN G CG   1 
ATOM   10699 C  CD   . GLN G 1 231 ? 7.039   -58.756 39.701  1.00 58.58  ? 438 GLN G CD   1 
ATOM   10700 O  OE1  . GLN G 1 231 ? 8.218   -58.489 39.450  1.00 63.35  ? 438 GLN G OE1  1 
ATOM   10701 N  NE2  . GLN G 1 231 ? 6.563   -58.767 40.929  1.00 61.72  ? 438 GLN G NE2  1 
ATOM   10702 N  N    . LYS G 1 232 ? 6.519   -61.157 35.198  1.00 60.30  ? 439 LYS G N    1 
ATOM   10703 C  CA   . LYS G 1 232 ? 6.089   -62.433 34.665  1.00 62.68  ? 439 LYS G CA   1 
ATOM   10704 C  C    . LYS G 1 232 ? 6.525   -62.476 33.218  1.00 62.56  ? 439 LYS G C    1 
ATOM   10705 O  O    . LYS G 1 232 ? 6.249   -61.542 32.462  1.00 63.80  ? 439 LYS G O    1 
ATOM   10706 C  CB   . LYS G 1 232 ? 4.570   -62.616 34.757  1.00 65.88  ? 439 LYS G CB   1 
ATOM   10707 C  CG   . LYS G 1 232 ? 4.117   -64.064 34.665  1.00 64.76  ? 439 LYS G CG   1 
ATOM   10708 C  CD   . LYS G 1 232 ? 2.707   -64.172 34.113  1.00 68.20  ? 439 LYS G CD   1 
ATOM   10709 C  CE   . LYS G 1 232 ? 2.174   -65.595 34.236  1.00 64.42  ? 439 LYS G CE   1 
ATOM   10710 N  NZ   . LYS G 1 232 ? 3.162   -66.577 33.693  1.00 64.01  ? 439 LYS G NZ   1 
ATOM   10711 N  N    . THR G 1 233 ? 7.201   -63.552 32.837  1.00 63.63  ? 440 THR G N    1 
ATOM   10712 C  CA   . THR G 1 233 ? 7.635   -63.712 31.463  1.00 68.16  ? 440 THR G CA   1 
ATOM   10713 C  C    . THR G 1 233 ? 6.550   -64.436 30.679  1.00 70.10  ? 440 THR G C    1 
ATOM   10714 O  O    . THR G 1 233 ? 5.525   -64.851 31.223  1.00 74.58  ? 440 THR G O    1 
ATOM   10715 C  CB   . THR G 1 233 ? 8.958   -64.472 31.393  1.00 68.17  ? 440 THR G CB   1 
ATOM   10716 O  OG1  . THR G 1 233 ? 8.785   -65.771 31.985  1.00 70.15  ? 440 THR G OG1  1 
ATOM   10717 C  CG2  . THR G 1 233 ? 10.074  -63.691 32.145  1.00 59.88  ? 440 THR G CG2  1 
ATOM   10718 N  N    . ASP G 1 234 ? 6.799   -64.618 29.387  1.00 71.43  ? 441 ASP G N    1 
ATOM   10719 C  CA   . ASP G 1 234 ? 5.804   -65.138 28.456  1.00 76.06  ? 441 ASP G CA   1 
ATOM   10720 C  C    . ASP G 1 234 ? 6.489   -66.101 27.499  1.00 78.88  ? 441 ASP G C    1 
ATOM   10721 O  O    . ASP G 1 234 ? 7.003   -65.687 26.452  1.00 79.97  ? 441 ASP G O    1 
ATOM   10722 C  CB   . ASP G 1 234 ? 5.131   -63.994 27.695  1.00 65.58  ? 441 ASP G CB   1 
ATOM   10723 C  CG   . ASP G 1 234 ? 4.107   -64.472 26.708  1.00 69.88  ? 441 ASP G CG   1 
ATOM   10724 O  OD1  . ASP G 1 234 ? 3.998   -65.693 26.489  1.00 75.17  ? 441 ASP G OD1  1 
ATOM   10725 O  OD2  . ASP G 1 234 ? 3.402   -63.618 26.139  1.00 77.51  ? 441 ASP G OD2  1 
ATOM   10726 N  N    . PRO G 1 235 ? 6.481   -67.404 27.804  1.00 81.60  ? 442 PRO G N    1 
ATOM   10727 C  CA   . PRO G 1 235 ? 7.174   -68.369 26.931  1.00 77.15  ? 442 PRO G CA   1 
ATOM   10728 C  C    . PRO G 1 235 ? 6.831   -68.240 25.460  1.00 77.27  ? 442 PRO G C    1 
ATOM   10729 O  O    . PRO G 1 235 ? 7.676   -68.561 24.616  1.00 80.39  ? 442 PRO G O    1 
ATOM   10730 C  CB   . PRO G 1 235 ? 6.728   -69.718 27.499  1.00 80.30  ? 442 PRO G CB   1 
ATOM   10731 C  CG   . PRO G 1 235 ? 6.534   -69.442 28.950  1.00 82.62  ? 442 PRO G CG   1 
ATOM   10732 C  CD   . PRO G 1 235 ? 5.919   -68.058 28.999  1.00 84.58  ? 442 PRO G CD   1 
ATOM   10733 N  N    . LYS G 1 236 ? 5.635   -67.744 25.120  1.00 79.57  ? 443 LYS G N    1 
ATOM   10734 C  CA   . LYS G 1 236 ? 5.255   -67.557 23.721  1.00 77.68  ? 443 LYS G CA   1 
ATOM   10735 C  C    . LYS G 1 236 ? 5.984   -66.401 23.049  1.00 76.21  ? 443 LYS G C    1 
ATOM   10736 O  O    . LYS G 1 236 ? 5.821   -66.219 21.838  1.00 78.91  ? 443 LYS G O    1 
ATOM   10737 C  CB   . LYS G 1 236 ? 3.742   -67.333 23.605  1.00 71.47  ? 443 LYS G CB   1 
ATOM   10738 N  N    . ASP G 1 237 ? 6.775   -65.619 23.801  1.00 74.52  ? 444 ASP G N    1 
ATOM   10739 C  CA   . ASP G 1 237 ? 7.405   -64.392 23.322  1.00 74.43  ? 444 ASP G CA   1 
ATOM   10740 C  C    . ASP G 1 237 ? 8.331   -63.846 24.402  1.00 72.80  ? 444 ASP G C    1 
ATOM   10741 O  O    . ASP G 1 237 ? 7.901   -63.055 25.253  1.00 74.58  ? 444 ASP G O    1 
ATOM   10742 C  CB   . ASP G 1 237 ? 6.341   -63.358 22.940  1.00 70.32  ? 444 ASP G CB   1 
ATOM   10743 C  CG   . ASP G 1 237 ? 6.913   -61.976 22.684  1.00 72.26  ? 444 ASP G CG   1 
ATOM   10744 O  OD1  . ASP G 1 237 ? 8.141   -61.828 22.491  1.00 66.07  ? 444 ASP G OD1  1 
ATOM   10745 O  OD2  . ASP G 1 237 ? 6.101   -61.022 22.661  1.00 78.21  ? 444 ASP G OD2  1 
ATOM   10746 N  N    . PRO G 1 238 ? 9.603   -64.224 24.394  1.00 67.36  ? 445 PRO G N    1 
ATOM   10747 C  CA   . PRO G 1 238 ? 10.528  -63.708 25.405  1.00 71.94  ? 445 PRO G CA   1 
ATOM   10748 C  C    . PRO G 1 238 ? 10.874  -62.257 25.129  1.00 72.10  ? 445 PRO G C    1 
ATOM   10749 O  O    . PRO G 1 238 ? 10.695  -61.739 24.022  1.00 70.38  ? 445 PRO G O    1 
ATOM   10750 C  CB   . PRO G 1 238 ? 11.763  -64.599 25.247  1.00 73.35  ? 445 PRO G CB   1 
ATOM   10751 C  CG   . PRO G 1 238 ? 11.770  -64.915 23.772  1.00 69.86  ? 445 PRO G CG   1 
ATOM   10752 C  CD   . PRO G 1 238 ? 10.296  -65.023 23.367  1.00 71.33  ? 445 PRO G CD   1 
ATOM   10753 N  N    . ALA G 1 239 ? 11.386  -61.600 26.168  1.00 69.83  ? 446 ALA G N    1 
ATOM   10754 C  CA   . ALA G 1 239 ? 11.869  -60.225 26.047  1.00 75.66  ? 446 ALA G CA   1 
ATOM   10755 C  C    . ALA G 1 239 ? 13.344  -60.242 25.635  1.00 71.12  ? 446 ALA G C    1 
ATOM   10756 O  O    . ALA G 1 239 ? 14.263  -59.973 26.416  1.00 68.33  ? 446 ALA G O    1 
ATOM   10757 C  CB   . ALA G 1 239 ? 11.646  -59.468 27.349  1.00 69.51  ? 446 ALA G CB   1 
ATOM   10758 N  N    . ASN G 1 240 ? 13.559  -60.558 24.363  1.00 67.90  ? 447 ASN G N    1 
ATOM   10759 C  CA   . ASN G 1 240 ? 14.935  -60.583 23.819  1.00 67.44  ? 447 ASN G CA   1 
ATOM   10760 C  C    . ASN G 1 240 ? 15.031  -59.429 22.830  1.00 70.88  ? 447 ASN G C    1 
ATOM   10761 O  O    . ASN G 1 240 ? 14.179  -59.365 21.933  1.00 69.64  ? 447 ASN G O    1 
ATOM   10762 C  CB   . ASN G 1 240 ? 15.248  -61.940 23.196  1.00 68.57  ? 447 ASN G CB   1 
ATOM   10763 C  CG   . ASN G 1 240 ? 15.559  -63.018 24.212  1.00 76.35  ? 447 ASN G CG   1 
ATOM   10764 O  OD1  . ASN G 1 240 ? 15.186  -62.918 25.377  1.00 76.60  ? 447 ASN G OD1  1 
ATOM   10765 N  ND2  . ASN G 1 240 ? 16.244  -64.061 23.775  1.00 79.35  ? 447 ASN G ND2  1 
ATOM   10766 N  N    . TYR G 1 241 ? 16.021  -58.551 22.993  1.00 70.90  ? 448 TYR G N    1 
ATOM   10767 C  CA   . TYR G 1 241 ? 16.103  -57.340 22.140  1.00 70.25  ? 448 TYR G CA   1 
ATOM   10768 C  C    . TYR G 1 241 ? 17.372  -57.319 21.291  1.00 71.13  ? 448 TYR G C    1 
ATOM   10769 O  O    . TYR G 1 241 ? 18.435  -57.700 21.788  1.00 61.96  ? 448 TYR G O    1 
ATOM   10770 N  N    . ILE G 1 242 ? 17.245  -56.861 20.044  1.00 69.03  ? 449 ILE G N    1 
ATOM   10771 C  CA   . ILE G 1 242 ? 18.437  -56.728 19.155  1.00 73.91  ? 449 ILE G CA   1 
ATOM   10772 C  C    . ILE G 1 242 ? 18.783  -55.243 19.001  1.00 74.83  ? 449 ILE G C    1 
ATOM   10773 O  O    . ILE G 1 242 ? 17.879  -54.447 18.703  1.00 72.32  ? 449 ILE G O    1 
ATOM   10774 C  CB   . ILE G 1 242 ? 18.233  -57.447 17.803  1.00 74.48  ? 449 ILE G CB   1 
ATOM   10775 C  CG1  . ILE G 1 242 ? 19.250  -57.003 16.748  1.00 79.16  ? 449 ILE G CG1  1 
ATOM   10776 C  CG2  . ILE G 1 242 ? 16.807  -57.303 17.291  1.00 67.77  ? 449 ILE G CG2  1 
ATOM   10777 C  CD1  . ILE G 1 242 ? 20.553  -57.764 16.794  1.00 83.14  ? 449 ILE G CD1  1 
ATOM   10778 N  N    . LEU G 1 243 ? 20.052  -54.895 19.215  1.00 72.27  ? 450 LEU G N    1 
ATOM   10779 C  CA   . LEU G 1 243 ? 20.508  -53.492 19.089  1.00 71.40  ? 450 LEU G CA   1 
ATOM   10780 C  C    . LEU G 1 243 ? 20.190  -52.993 17.689  1.00 74.42  ? 450 LEU G C    1 
ATOM   10781 O  O    . LEU G 1 243 ? 20.682  -53.581 16.721  1.00 75.67  ? 450 LEU G O    1 
ATOM   10782 C  CB   . LEU G 1 243 ? 22.010  -53.427 19.358  1.00 72.19  ? 450 LEU G CB   1 
ATOM   10783 C  CG   . LEU G 1 243 ? 22.635  -52.034 19.383  1.00 73.62  ? 450 LEU G CG   1 
ATOM   10784 C  CD1  . LEU G 1 243 ? 21.787  -51.060 20.184  1.00 69.38  ? 450 LEU G CD1  1 
ATOM   10785 C  CD2  . LEU G 1 243 ? 24.036  -52.102 19.957  1.00 67.50  ? 450 LEU G CD2  1 
ATOM   10786 N  N    . HIS G 1 244 ? 19.395  -51.937 17.615  1.00 74.00  ? 451 HIS G N    1 
ATOM   10787 C  CA   . HIS G 1 244 ? 19.038  -51.343 16.301  1.00 67.94  ? 451 HIS G CA   1 
ATOM   10788 C  C    . HIS G 1 244 ? 19.749  -50.011 16.105  1.00 71.07  ? 451 HIS G C    1 
ATOM   10789 O  O    . HIS G 1 244 ? 20.256  -49.794 15.002  1.00 77.34  ? 451 HIS G O    1 
ATOM   10790 C  CB   . HIS G 1 244 ? 17.528  -51.135 16.203  1.00 67.61  ? 451 HIS G CB   1 
ATOM   10791 C  CG   . HIS G 1 244 ? 17.055  -50.585 14.903  1.00 66.43  ? 451 HIS G CG   1 
ATOM   10792 N  ND1  . HIS G 1 244 ? 16.382  -49.389 14.817  1.00 68.27  ? 451 HIS G ND1  1 
ATOM   10793 C  CD2  . HIS G 1 244 ? 17.129  -51.071 13.647  1.00 68.00  ? 451 HIS G CD2  1 
ATOM   10794 C  CE1  . HIS G 1 244 ? 16.070  -49.153 13.561  1.00 65.74  ? 451 HIS G CE1  1 
ATOM   10795 N  NE2  . HIS G 1 244 ? 16.518  -50.168 12.826  1.00 65.45  ? 451 HIS G NE2  1 
ATOM   10796 N  N    . ALA G 1 245 ? 19.779  -49.163 17.135  1.00 75.20  ? 452 ALA G N    1 
ATOM   10797 C  CA   . ALA G 1 245 ? 20.343  -47.805 16.970  1.00 70.27  ? 452 ALA G CA   1 
ATOM   10798 C  C    . ALA G 1 245 ? 21.217  -47.396 18.149  1.00 69.20  ? 452 ALA G C    1 
ATOM   10799 O  O    . ALA G 1 245 ? 20.909  -47.777 19.279  1.00 68.11  ? 452 ALA G O    1 
ATOM   10800 C  CB   . ALA G 1 245 ? 19.228  -46.820 16.790  1.00 68.16  ? 452 ALA G CB   1 
ATOM   10801 N  N    . VAL G 1 246 ? 22.254  -46.610 17.875  1.00 74.58  ? 453 VAL G N    1 
ATOM   10802 C  CA   . VAL G 1 246 ? 23.143  -46.094 18.952  1.00 76.35  ? 453 VAL G CA   1 
ATOM   10803 C  C    . VAL G 1 246 ? 23.307  -44.589 18.731  1.00 77.24  ? 453 VAL G C    1 
ATOM   10804 O  O    . VAL G 1 246 ? 24.103  -44.211 17.862  1.00 81.33  ? 453 VAL G O    1 
ATOM   10805 C  CB   . VAL G 1 246 ? 24.508  -46.806 18.961  1.00 75.76  ? 453 VAL G CB   1 
ATOM   10806 C  CG1  . VAL G 1 246 ? 25.353  -46.393 20.151  1.00 77.31  ? 453 VAL G CG1  1 
ATOM   10807 C  CG2  . VAL G 1 246 ? 24.393  -48.318 18.894  1.00 68.48  ? 453 VAL G CG2  1 
ATOM   10808 N  N    . LEU G 1 247 ? 22.543  -43.770 19.454  1.00 72.95  ? 454 LEU G N    1 
ATOM   10809 C  CA   . LEU G 1 247 ? 22.684  -42.294 19.353  1.00 70.87  ? 454 LEU G CA   1 
ATOM   10810 C  C    . LEU G 1 247 ? 23.890  -41.909 20.210  1.00 69.36  ? 454 LEU G C    1 
ATOM   10811 O  O    . LEU G 1 247 ? 23.878  -42.192 21.414  1.00 68.86  ? 454 LEU G O    1 
ATOM   10812 C  CB   . LEU G 1 247 ? 21.374  -41.617 19.763  1.00 63.62  ? 454 LEU G CB   1 
ATOM   10813 C  CG   . LEU G 1 247 ? 20.220  -41.820 18.785  1.00 73.19  ? 454 LEU G CG   1 
ATOM   10814 C  CD1  . LEU G 1 247 ? 19.258  -42.892 19.270  1.00 64.37  ? 454 LEU G CD1  1 
ATOM   10815 C  CD2  . LEU G 1 247 ? 19.484  -40.519 18.529  1.00 66.21  ? 454 LEU G CD2  1 
ATOM   10816 N  N    . VAL G 1 248 ? 24.893  -41.297 19.595  1.00 63.29  ? 455 VAL G N    1 
ATOM   10817 C  CA   . VAL G 1 248 ? 26.175  -41.046 20.299  1.00 72.13  ? 455 VAL G CA   1 
ATOM   10818 C  C    . VAL G 1 248 ? 26.427  -39.547 20.441  1.00 70.92  ? 455 VAL G C    1 
ATOM   10819 O  O    . VAL G 1 248 ? 26.144  -38.805 19.495  1.00 69.97  ? 455 VAL G O    1 
ATOM   10820 C  CB   . VAL G 1 248 ? 27.288  -41.756 19.507  1.00 73.62  ? 455 VAL G CB   1 
ATOM   10821 C  CG1  . VAL G 1 248 ? 28.688  -41.295 19.849  1.00 73.47  ? 455 VAL G CG1  1 
ATOM   10822 C  CG2  . VAL G 1 248 ? 27.177  -43.261 19.619  1.00 72.69  ? 455 VAL G CG2  1 
ATOM   10823 N  N    . HIS G 1 249 ? 26.952  -39.142 21.593  1.00 63.93  ? 456 HIS G N    1 
ATOM   10824 C  CA   . HIS G 1 249 ? 27.246  -37.712 21.843  1.00 68.97  ? 456 HIS G CA   1 
ATOM   10825 C  C    . HIS G 1 249 ? 28.729  -37.500 22.126  1.00 71.29  ? 456 HIS G C    1 
ATOM   10826 O  O    . HIS G 1 249 ? 29.283  -38.241 22.948  1.00 70.10  ? 456 HIS G O    1 
ATOM   10827 C  CB   . HIS G 1 249 ? 26.419  -37.212 23.028  1.00 71.82  ? 456 HIS G CB   1 
ATOM   10828 C  CG   . HIS G 1 249 ? 26.607  -35.770 23.346  1.00 69.22  ? 456 HIS G CG   1 
ATOM   10829 N  ND1  . HIS G 1 249 ? 27.398  -35.347 24.387  1.00 67.50  ? 456 HIS G ND1  1 
ATOM   10830 C  CD2  . HIS G 1 249 ? 26.103  -34.659 22.776  1.00 68.21  ? 456 HIS G CD2  1 
ATOM   10831 C  CE1  . HIS G 1 249 ? 27.387  -34.038 24.440  1.00 72.79  ? 456 HIS G CE1  1 
ATOM   10832 N  NE2  . HIS G 1 249 ? 26.605  -33.595 23.464  1.00 69.98  ? 456 HIS G NE2  1 
ATOM   10833 N  N    . SER G 1 250 ? 29.316  -36.513 21.459  1.00 71.87  ? 457 SER G N    1 
ATOM   10834 C  CA   . SER G 1 250 ? 30.735  -36.160 21.674  1.00 72.38  ? 457 SER G CA   1 
ATOM   10835 C  C    . SER G 1 250 ? 30.782  -34.732 22.192  1.00 68.70  ? 457 SER G C    1 
ATOM   10836 O  O    . SER G 1 250 ? 30.515  -33.838 21.400  1.00 71.05  ? 457 SER G O    1 
ATOM   10837 C  CB   . SER G 1 250 ? 31.517  -36.263 20.400  1.00 72.65  ? 457 SER G CB   1 
ATOM   10838 O  OG   . SER G 1 250 ? 30.733  -35.913 19.272  1.00 76.76  ? 457 SER G OG   1 
ATOM   10839 N  N    . GLY G 1 251 ? 31.110  -34.537 23.462  1.00 72.10  ? 458 GLY G N    1 
ATOM   10840 C  CA   . GLY G 1 251 ? 31.270  -33.169 23.974  1.00 69.53  ? 458 GLY G CA   1 
ATOM   10841 C  C    . GLY G 1 251 ? 31.005  -33.041 25.455  1.00 72.08  ? 458 GLY G C    1 
ATOM   10842 O  O    . GLY G 1 251 ? 31.455  -33.913 26.208  1.00 69.50  ? 458 GLY G O    1 
ATOM   10843 N  N    . ASP G 1 252 ? 30.309  -31.977 25.848  1.00 77.46  ? 459 ASP G N    1 
ATOM   10844 C  CA   . ASP G 1 252 ? 30.018  -31.699 27.276  1.00 78.76  ? 459 ASP G CA   1 
ATOM   10845 C  C    . ASP G 1 252 ? 28.512  -31.545 27.493  1.00 77.56  ? 459 ASP G C    1 
ATOM   10846 O  O    . ASP G 1 252 ? 27.741  -31.737 26.542  1.00 73.71  ? 459 ASP G O    1 
ATOM   10847 C  CB   . ASP G 1 252 ? 30.718  -30.411 27.712  1.00 76.11  ? 459 ASP G CB   1 
ATOM   10848 C  CG   . ASP G 1 252 ? 31.476  -30.519 29.023  1.00 85.20  ? 459 ASP G CG   1 
ATOM   10849 O  OD1  . ASP G 1 252 ? 31.438  -31.602 29.644  1.00 91.58  ? 459 ASP G OD1  1 
ATOM   10850 O  OD2  . ASP G 1 252 ? 32.096  -29.514 29.414  1.00 83.42  ? 459 ASP G OD2  1 
ATOM   10851 N  N    . ASN G 1 253 ? 28.116  -31.172 28.706  1.00 30.00  ? 460 ASN G N    1 
ATOM   10852 C  CA   . ASN G 1 253 ? 26.689  -30.929 29.014  1.00 30.00  ? 460 ASN G CA   1 
ATOM   10853 C  C    . ASN G 1 253 ? 26.179  -29.756 28.187  1.00 30.00  ? 460 ASN G C    1 
ATOM   10854 O  O    . ASN G 1 253 ? 25.032  -29.830 27.727  1.00 30.00  ? 460 ASN G O    1 
ATOM   10855 C  CB   . ASN G 1 253 ? 26.526  -30.552 30.484  1.00 30.00  ? 460 ASN G CB   1 
ATOM   10856 C  CG   . ASN G 1 253 ? 25.882  -31.627 31.328  1.00 30.00  ? 460 ASN G CG   1 
ATOM   10857 O  OD1  . ASN G 1 253 ? 26.499  -32.647 31.613  1.00 30.00  ? 460 ASN G OD1  1 
ATOM   10858 N  ND2  . ASN G 1 253 ? 24.651  -31.397 31.749  1.00 30.00  ? 460 ASN G ND2  1 
ATOM   10859 N  N    . HIS G 1 254 ? 27.013  -28.734 27.989  1.00 86.25  ? 461 HIS G N    1 
ATOM   10860 C  CA   . HIS G 1 254 ? 26.572  -27.474 27.338  1.00 79.54  ? 461 HIS G CA   1 
ATOM   10861 C  C    . HIS G 1 254 ? 26.692  -27.520 25.812  1.00 78.22  ? 461 HIS G C    1 
ATOM   10862 O  O    . HIS G 1 254 ? 26.023  -26.700 25.165  1.00 75.70  ? 461 HIS G O    1 
ATOM   10863 C  CB   . HIS G 1 254 ? 27.358  -26.314 27.954  1.00 80.15  ? 461 HIS G CB   1 
ATOM   10864 C  CG   . HIS G 1 254 ? 27.589  -26.453 29.419  1.00 84.98  ? 461 HIS G CG   1 
ATOM   10865 N  ND1  . HIS G 1 254 ? 26.561  -26.383 30.335  1.00 83.68  ? 461 HIS G ND1  1 
ATOM   10866 C  CD2  . HIS G 1 254 ? 28.720  -26.664 30.126  1.00 89.99  ? 461 HIS G CD2  1 
ATOM   10867 C  CE1  . HIS G 1 254 ? 27.047  -26.543 31.548  1.00 90.35  ? 461 HIS G CE1  1 
ATOM   10868 N  NE2  . HIS G 1 254 ? 28.370  -26.717 31.447  1.00 97.86  ? 461 HIS G NE2  1 
ATOM   10869 N  N    . GLY G 1 255 ? 27.505  -28.422 25.260  1.00 79.52  ? 462 GLY G N    1 
ATOM   10870 C  CA   . GLY G 1 255 ? 27.669  -28.453 23.823  1.00 69.29  ? 462 GLY G CA   1 
ATOM   10871 C  C    . GLY G 1 255 ? 28.494  -29.641 23.398  1.00 70.02  ? 462 GLY G C    1 
ATOM   10872 O  O    . GLY G 1 255 ? 29.206  -30.256 24.204  1.00 68.26  ? 462 GLY G O    1 
ATOM   10873 N  N    . GLY G 1 256 ? 28.393  -29.946 22.112  1.00 66.28  ? 463 GLY G N    1 
ATOM   10874 C  CA   . GLY G 1 256 ? 29.006  -31.133 21.561  1.00 66.64  ? 463 GLY G CA   1 
ATOM   10875 C  C    . GLY G 1 256 ? 28.335  -31.504 20.252  1.00 71.27  ? 463 GLY G C    1 
ATOM   10876 O  O    . GLY G 1 256 ? 27.605  -30.707 19.661  1.00 69.59  ? 463 GLY G O    1 
ATOM   10877 N  N    . HIS G 1 257 ? 28.595  -32.732 19.786  1.00 72.94  ? 464 HIS G N    1 
ATOM   10878 C  CA   . HIS G 1 257 ? 28.027  -33.193 18.491  1.00 72.72  ? 464 HIS G CA   1 
ATOM   10879 C  C    . HIS G 1 257 ? 27.161  -34.431 18.694  1.00 70.37  ? 464 HIS G C    1 
ATOM   10880 O  O    . HIS G 1 257 ? 27.392  -35.154 19.668  1.00 71.02  ? 464 HIS G O    1 
ATOM   10881 C  CB   . HIS G 1 257 ? 29.133  -33.488 17.473  1.00 68.50  ? 464 HIS G CB   1 
ATOM   10882 C  CG   . HIS G 1 257 ? 28.647  -33.624 16.072  1.00 68.44  ? 464 HIS G CG   1 
ATOM   10883 N  ND1  . HIS G 1 257 ? 28.078  -32.575 15.387  1.00 76.48  ? 464 HIS G ND1  1 
ATOM   10884 C  CD2  . HIS G 1 257 ? 28.626  -34.680 15.235  1.00 69.22  ? 464 HIS G CD2  1 
ATOM   10885 C  CE1  . HIS G 1 257 ? 27.736  -32.976 14.182  1.00 70.86  ? 464 HIS G CE1  1 
ATOM   10886 N  NE2  . HIS G 1 257 ? 28.056  -34.262 14.067  1.00 76.91  ? 464 HIS G NE2  1 
ATOM   10887 N  N    . TYR G 1 258 ? 26.222  -34.659 17.779  1.00 66.75  ? 465 TYR G N    1 
ATOM   10888 C  CA   . TYR G 1 258 ? 25.348  -35.849 17.862  1.00 66.57  ? 465 TYR G CA   1 
ATOM   10889 C  C    . TYR G 1 258 ? 25.428  -36.664 16.577  1.00 72.57  ? 465 TYR G C    1 
ATOM   10890 O  O    . TYR G 1 258 ? 25.349  -36.072 15.489  1.00 72.80  ? 465 TYR G O    1 
ATOM   10891 C  CB   . TYR G 1 258 ? 23.901  -35.441 18.105  1.00 67.97  ? 465 TYR G CB   1 
ATOM   10892 C  CG   . TYR G 1 258 ? 23.459  -35.502 19.538  1.00 68.44  ? 465 TYR G CG   1 
ATOM   10893 C  CD1  . TYR G 1 258 ? 23.496  -36.686 20.250  1.00 68.43  ? 465 TYR G CD1  1 
ATOM   10894 C  CD2  . TYR G 1 258 ? 22.999  -34.367 20.175  1.00 66.17  ? 465 TYR G CD2  1 
ATOM   10895 C  CE1  . TYR G 1 258 ? 23.084  -36.739 21.569  1.00 66.61  ? 465 TYR G CE1  1 
ATOM   10896 C  CE2  . TYR G 1 258 ? 22.575  -34.404 21.488  1.00 69.47  ? 465 TYR G CE2  1 
ATOM   10897 C  CZ   . TYR G 1 258 ? 22.621  -35.592 22.185  1.00 64.83  ? 465 TYR G CZ   1 
ATOM   10898 O  OH   . TYR G 1 258 ? 22.201  -35.614 23.476  1.00 63.62  ? 465 TYR G OH   1 
ATOM   10899 N  N    . VAL G 1 259 ? 25.527  -37.985 16.713  1.00 72.05  ? 466 VAL G N    1 
ATOM   10900 C  CA   . VAL G 1 259 ? 25.632  -38.899 15.541  1.00 74.15  ? 466 VAL G CA   1 
ATOM   10901 C  C    . VAL G 1 259 ? 24.858  -40.176 15.885  1.00 74.50  ? 466 VAL G C    1 
ATOM   10902 O  O    . VAL G 1 259 ? 24.850  -40.567 17.049  1.00 76.32  ? 466 VAL G O    1 
ATOM   10903 C  CB   . VAL G 1 259 ? 27.110  -39.163 15.187  1.00 71.46  ? 466 VAL G CB   1 
ATOM   10904 C  CG1  . VAL G 1 259 ? 27.945  -39.571 16.388  1.00 65.96  ? 466 VAL G CG1  1 
ATOM   10905 C  CG2  . VAL G 1 259 ? 27.288  -40.145 14.045  1.00 71.62  ? 466 VAL G CG2  1 
ATOM   10906 N  N    . VAL G 1 260 ? 24.194  -40.776 14.906  1.00 74.13  ? 467 VAL G N    1 
ATOM   10907 C  CA   . VAL G 1 260 ? 23.413  -41.983 15.149  1.00 80.15  ? 467 VAL G CA   1 
ATOM   10908 C  C    . VAL G 1 260 ? 23.965  -43.117 14.282  1.00 82.12  ? 467 VAL G C    1 
ATOM   10909 O  O    . VAL G 1 260 ? 24.011  -43.002 13.049  1.00 74.80  ? 467 VAL G O    1 
ATOM   10910 C  CB   . VAL G 1 260 ? 21.908  -41.760 14.904  1.00 70.85  ? 467 VAL G CB   1 
ATOM   10911 C  CG1  . VAL G 1 260 ? 21.620  -41.329 13.477  1.00 65.25  ? 467 VAL G CG1  1 
ATOM   10912 C  CG2  . VAL G 1 260 ? 21.118  -43.010 15.298  1.00 74.62  ? 467 VAL G CG2  1 
ATOM   10913 N  N    . TYR G 1 261 ? 24.421  -44.190 14.937  1.00 77.95  ? 468 TYR G N    1 
ATOM   10914 C  CA   . TYR G 1 261 ? 24.820  -45.422 14.270  1.00 77.63  ? 468 TYR G CA   1 
ATOM   10915 C  C    . TYR G 1 261 ? 23.611  -46.348 14.208  1.00 81.28  ? 468 TYR G C    1 
ATOM   10916 O  O    . TYR G 1 261 ? 22.823  -46.427 15.158  1.00 81.70  ? 468 TYR G O    1 
ATOM   10917 N  N    . LEU G 1 262 ? 23.473  -47.056 13.090  1.00 79.88  ? 469 LEU G N    1 
ATOM   10918 C  CA   . LEU G 1 262 ? 22.281  -47.851 12.825  1.00 82.05  ? 469 LEU G CA   1 
ATOM   10919 C  C    . LEU G 1 262 ? 22.619  -49.075 11.981  1.00 85.75  ? 469 LEU G C    1 
ATOM   10920 O  O    . LEU G 1 262 ? 23.385  -48.979 11.018  1.00 83.61  ? 469 LEU G O    1 
ATOM   10921 C  CB   . LEU G 1 262 ? 21.238  -47.009 12.090  1.00 75.30  ? 469 LEU G CB   1 
ATOM   10922 C  CG   . LEU G 1 262 ? 20.330  -46.125 12.915  1.00 75.81  ? 469 LEU G CG   1 
ATOM   10923 C  CD1  . LEU G 1 262 ? 19.826  -44.984 12.063  1.00 75.31  ? 469 LEU G CD1  1 
ATOM   10924 C  CD2  . LEU G 1 262 ? 19.191  -47.003 13.338  1.00 76.59  ? 469 LEU G CD2  1 
ATOM   10925 N  N    . ASN G 1 263 ? 22.030  -50.222 12.326  1.00 83.96  ? 470 ASN G N    1 
ATOM   10926 C  CA   . ASN G 1 263 ? 21.897  -51.310 11.359  1.00 82.60  ? 470 ASN G CA   1 
ATOM   10927 C  C    . ASN G 1 263 ? 20.418  -51.383 10.997  1.00 81.58  ? 470 ASN G C    1 
ATOM   10928 O  O    . ASN G 1 263 ? 19.656  -52.159 11.596  1.00 84.43  ? 470 ASN G O    1 
ATOM   10929 C  CB   . ASN G 1 263 ? 22.417  -52.645 11.898  1.00 83.31  ? 470 ASN G CB   1 
ATOM   10930 C  CG   . ASN G 1 263 ? 21.758  -53.054 13.186  1.00 82.49  ? 470 ASN G CG   1 
ATOM   10931 O  OD1  . ASN G 1 263 ? 21.990  -52.456 14.235  1.00 82.86  ? 470 ASN G OD1  1 
ATOM   10932 N  ND2  . ASN G 1 263 ? 20.931  -54.087 13.116  1.00 78.58  ? 470 ASN G ND2  1 
ATOM   10933 N  N    . PRO G 1 264 ? 19.970  -50.594 10.014  1.00 76.36  ? 471 PRO G N    1 
ATOM   10934 C  CA   . PRO G 1 264 ? 18.531  -50.311 9.866   1.00 74.38  ? 471 PRO G CA   1 
ATOM   10935 C  C    . PRO G 1 264 ? 17.659  -51.508 9.541   1.00 76.71  ? 471 PRO G C    1 
ATOM   10936 O  O    . PRO G 1 264 ? 16.452  -51.458 9.812   1.00 72.61  ? 471 PRO G O    1 
ATOM   10937 C  CB   . PRO G 1 264 ? 18.499  -49.291 8.719   1.00 72.54  ? 471 PRO G CB   1 
ATOM   10938 C  CG   . PRO G 1 264 ? 19.850  -48.694 8.704   1.00 75.39  ? 471 PRO G CG   1 
ATOM   10939 C  CD   . PRO G 1 264 ? 20.791  -49.780 9.106   1.00 81.68  ? 471 PRO G CD   1 
ATOM   10940 N  N    . LYS G 1 265 ? 18.209  -52.555 8.925   1.00 82.57  ? 472 LYS G N    1 
ATOM   10941 C  CA   . LYS G 1 265 ? 17.429  -53.734 8.573   1.00 77.60  ? 472 LYS G CA   1 
ATOM   10942 C  C    . LYS G 1 265 ? 17.372  -54.755 9.696   1.00 79.63  ? 472 LYS G C    1 
ATOM   10943 O  O    . LYS G 1 265 ? 16.594  -55.713 9.602   1.00 78.74  ? 472 LYS G O    1 
ATOM   10944 N  N    . GLY G 1 266 ? 18.225  -54.588 10.711  1.00 78.07  ? 473 GLY G N    1 
ATOM   10945 C  CA   . GLY G 1 266 ? 18.283  -55.542 11.835  1.00 76.46  ? 473 GLY G CA   1 
ATOM   10946 C  C    . GLY G 1 266 ? 19.227  -56.696 11.567  1.00 84.16  ? 473 GLY G C    1 
ATOM   10947 O  O    . GLY G 1 266 ? 19.272  -57.615 12.405  1.00 76.19  ? 473 GLY G O    1 
ATOM   10948 N  N    . ASP G 1 267 ? 19.994  -56.635 10.477  1.00 85.50  ? 474 ASP G N    1 
ATOM   10949 C  CA   . ASP G 1 267 ? 20.839  -57.756 10.074  1.00 80.14  ? 474 ASP G CA   1 
ATOM   10950 C  C    . ASP G 1 267 ? 22.235  -57.694 10.677  1.00 82.73  ? 474 ASP G C    1 
ATOM   10951 O  O    . ASP G 1 267 ? 22.884  -58.734 10.843  1.00 83.32  ? 474 ASP G O    1 
ATOM   10952 C  CB   . ASP G 1 267 ? 20.949  -57.775 8.558   1.00 74.08  ? 474 ASP G CB   1 
ATOM   10953 C  CG   . ASP G 1 267 ? 21.213  -56.406 7.997   1.00 82.08  ? 474 ASP G CG   1 
ATOM   10954 O  OD1  . ASP G 1 267 ? 21.935  -55.628 8.660   1.00 79.20  ? 474 ASP G OD1  1 
ATOM   10955 O  OD2  . ASP G 1 267 ? 20.692  -56.100 6.903   1.00 87.49  ? 474 ASP G OD2  1 
ATOM   10956 N  N    . GLY G 1 268 ? 22.727  -56.498 10.992  1.00 84.93  ? 475 GLY G N    1 
ATOM   10957 C  CA   . GLY G 1 268 ? 24.117  -56.353 11.468  1.00 79.57  ? 475 GLY G CA   1 
ATOM   10958 C  C    . GLY G 1 268 ? 24.925  -55.496 10.513  1.00 81.86  ? 475 GLY G C    1 
ATOM   10959 O  O    . GLY G 1 268 ? 26.111  -55.285 10.797  1.00 78.90  ? 475 GLY G O    1 
ATOM   10960 N  N    . LYS G 1 269 ? 24.310  -55.032 9.420   1.00 83.88  ? 476 LYS G N    1 
ATOM   10961 C  CA   . LYS G 1 269 ? 24.977  -54.163 8.414   1.00 83.96  ? 476 LYS G CA   1 
ATOM   10962 C  C    . LYS G 1 269 ? 24.816  -52.717 8.873   1.00 89.80  ? 476 LYS G C    1 
ATOM   10963 O  O    . LYS G 1 269 ? 23.769  -52.122 8.571   1.00 91.20  ? 476 LYS G O    1 
ATOM   10964 N  N    . TRP G 1 270 ? 25.836  -52.170 9.528   1.00 88.98  ? 477 TRP G N    1 
ATOM   10965 C  CA   . TRP G 1 270 ? 25.735  -50.822 10.132  1.00 86.99  ? 477 TRP G CA   1 
ATOM   10966 C  C    . TRP G 1 270 ? 26.250  -49.678 9.270   1.00 89.67  ? 477 TRP G C    1 
ATOM   10967 O  O    . TRP G 1 270 ? 27.289  -49.841 8.627   1.00 89.63  ? 477 TRP G O    1 
ATOM   10968 N  N    . CYS G 1 271 ? 25.514  -48.573 9.257   1.00 82.47  ? 478 CYS G N    1 
ATOM   10969 C  CA   . CYS G 1 271 ? 25.998  -47.346 8.592   1.00 85.18  ? 478 CYS G CA   1 
ATOM   10970 C  C    . CYS G 1 271 ? 26.189  -46.304 9.709   1.00 85.20  ? 478 CYS G C    1 
ATOM   10971 O  O    . CYS G 1 271 ? 25.955  -46.640 10.885  1.00 83.43  ? 478 CYS G O    1 
ATOM   10972 C  CB   . CYS G 1 271 ? 24.998  -46.878 7.546   1.00 85.31  ? 478 CYS G CB   1 
ATOM   10973 S  SG   . CYS G 1 271 ? 24.789  -48.033 6.167   1.00 89.24  ? 478 CYS G SG   1 
ATOM   10974 N  N    . LYS G 1 272 ? 26.612  -45.091 9.366   1.00 83.76  ? 479 LYS G N    1 
ATOM   10975 C  CA   . LYS G 1 272 ? 26.795  -44.030 10.386  1.00 81.43  ? 479 LYS G CA   1 
ATOM   10976 C  C    . LYS G 1 272 ? 26.329  -42.707 9.795   1.00 80.25  ? 479 LYS G C    1 
ATOM   10977 O  O    . LYS G 1 272 ? 26.893  -42.301 8.784   1.00 85.38  ? 479 LYS G O    1 
ATOM   10978 C  CB   . LYS G 1 272 ? 28.255  -43.950 10.836  1.00 76.20  ? 479 LYS G CB   1 
ATOM   10979 C  CG   . LYS G 1 272 ? 28.549  -42.940 11.935  1.00 69.02  ? 479 LYS G CG   1 
ATOM   10980 N  N    . PHE G 1 273 ? 25.359  -42.061 10.434  1.00 76.47  ? 480 PHE G N    1 
ATOM   10981 C  CA   . PHE G 1 273 ? 24.802  -40.795 9.902   1.00 79.46  ? 480 PHE G CA   1 
ATOM   10982 C  C    . PHE G 1 273 ? 25.431  -39.579 10.585  1.00 82.23  ? 480 PHE G C    1 
ATOM   10983 O  O    . PHE G 1 273 ? 24.965  -39.228 11.680  1.00 79.11  ? 480 PHE G O    1 
ATOM   10984 N  N    . ASP G 1 274 ? 26.460  -38.974 9.980   1.00 81.63  ? 481 ASP G N    1 
ATOM   10985 C  CA   . ASP G 1 274 ? 27.011  -37.700 10.508  1.00 77.19  ? 481 ASP G CA   1 
ATOM   10986 C  C    . ASP G 1 274 ? 26.320  -36.602 9.721   1.00 80.70  ? 481 ASP G C    1 
ATOM   10987 O  O    . ASP G 1 274 ? 26.959  -36.057 8.813   1.00 84.56  ? 481 ASP G O    1 
ATOM   10988 C  CB   . ASP G 1 274 ? 28.528  -37.586 10.381  1.00 80.16  ? 481 ASP G CB   1 
ATOM   10989 C  CG   . ASP G 1 274 ? 29.165  -36.604 11.350  1.00 82.75  ? 481 ASP G CG   1 
ATOM   10990 O  OD1  . ASP G 1 274 ? 28.629  -35.493 11.504  1.00 81.78  ? 481 ASP G OD1  1 
ATOM   10991 O  OD2  . ASP G 1 274 ? 30.201  -36.958 11.939  1.00 82.18  ? 481 ASP G OD2  1 
ATOM   10992 N  N    . ASP G 1 275 ? 25.053  -36.348 10.037  1.00 81.99  ? 482 ASP G N    1 
ATOM   10993 C  CA   . ASP G 1 275 ? 24.251  -35.320 9.330   1.00 80.54  ? 482 ASP G CA   1 
ATOM   10994 C  C    . ASP G 1 275 ? 24.289  -35.616 7.835   1.00 82.05  ? 482 ASP G C    1 
ATOM   10995 O  O    . ASP G 1 275 ? 23.542  -36.490 7.413   1.00 84.75  ? 482 ASP G O    1 
ATOM   10996 C  CB   . ASP G 1 275 ? 24.706  -33.901 9.690   1.00 79.58  ? 482 ASP G CB   1 
ATOM   10997 C  CG   . ASP G 1 275 ? 24.860  -33.647 11.180  1.00 81.21  ? 482 ASP G CG   1 
ATOM   10998 O  OD1  . ASP G 1 275 ? 24.119  -34.265 11.964  1.00 79.29  ? 482 ASP G OD1  1 
ATOM   10999 O  OD2  . ASP G 1 275 ? 25.722  -32.829 11.540  1.00 78.99  ? 482 ASP G OD2  1 
ATOM   11000 N  N    . ASP G 1 276 ? 25.173  -34.955 7.097   1.00 82.34  ? 483 ASP G N    1 
ATOM   11001 C  CA   . ASP G 1 276 ? 25.243  -35.094 5.621   1.00 85.94  ? 483 ASP G CA   1 
ATOM   11002 C  C    . ASP G 1 276 ? 25.975  -36.369 5.201   1.00 89.13  ? 483 ASP G C    1 
ATOM   11003 O  O    . ASP G 1 276 ? 25.658  -36.868 4.113   1.00 90.32  ? 483 ASP G O    1 
ATOM   11004 C  CB   . ASP G 1 276 ? 25.918  -33.857 5.020   1.00 85.60  ? 483 ASP G CB   1 
ATOM   11005 C  CG   . ASP G 1 276 ? 27.318  -33.573 5.528   1.00 81.77  ? 483 ASP G CG   1 
ATOM   11006 O  OD1  . ASP G 1 276 ? 27.502  -33.516 6.756   1.00 85.89  ? 483 ASP G OD1  1 
ATOM   11007 O  OD2  . ASP G 1 276 ? 28.212  -33.395 4.686   1.00 89.13  ? 483 ASP G OD2  1 
ATOM   11008 N  N    . VAL G 1 277 ? 26.890  -36.888 6.023   1.00 84.70  ? 484 VAL G N    1 
ATOM   11009 C  CA   . VAL G 1 277 ? 27.729  -38.042 5.588   1.00 80.78  ? 484 VAL G CA   1 
ATOM   11010 C  C    . VAL G 1 277 ? 27.215  -39.361 6.155   1.00 79.36  ? 484 VAL G C    1 
ATOM   11011 O  O    . VAL G 1 277 ? 27.553  -39.672 7.306   1.00 80.07  ? 484 VAL G O    1 
ATOM   11012 C  CB   . VAL G 1 277 ? 29.199  -37.825 5.988   1.00 84.82  ? 484 VAL G CB   1 
ATOM   11013 C  CG1  . VAL G 1 277 ? 30.138  -38.728 5.203   1.00 80.43  ? 484 VAL G CG1  1 
ATOM   11014 C  CG2  . VAL G 1 277 ? 29.607  -36.368 5.844   1.00 83.99  ? 484 VAL G CG2  1 
ATOM   11015 N  N    . VAL G 1 278 ? 26.456  -40.106 5.358   1.00 82.48  ? 485 VAL G N    1 
ATOM   11016 C  CA   . VAL G 1 278 ? 26.024  -41.463 5.792   1.00 83.64  ? 485 VAL G CA   1 
ATOM   11017 C  C    . VAL G 1 278 ? 27.124  -42.415 5.323   1.00 85.39  ? 485 VAL G C    1 
ATOM   11018 O  O    . VAL G 1 278 ? 27.358  -42.504 4.108   1.00 84.88  ? 485 VAL G O    1 
ATOM   11019 C  CB   . VAL G 1 278 ? 24.619  -41.821 5.271   1.00 82.07  ? 485 VAL G CB   1 
ATOM   11020 C  CG1  . VAL G 1 278 ? 24.392  -41.382 3.833   1.00 81.82  ? 485 VAL G CG1  1 
ATOM   11021 C  CG2  . VAL G 1 278 ? 24.281  -43.291 5.462   1.00 84.63  ? 485 VAL G CG2  1 
ATOM   11022 N  N    . SER G 1 279 ? 27.819  -43.056 6.259   1.00 84.73  ? 486 SER G N    1 
ATOM   11023 C  CA   . SER G 1 279 ? 28.988  -43.889 5.879   1.00 86.72  ? 486 SER G CA   1 
ATOM   11024 C  C    . SER G 1 279 ? 28.875  -45.302 6.447   1.00 89.50  ? 486 SER G C    1 
ATOM   11025 O  O    . SER G 1 279 ? 28.903  -45.446 7.677   1.00 89.13  ? 486 SER G O    1 
ATOM   11026 C  CB   . SER G 1 279 ? 30.277  -43.232 6.318   1.00 84.55  ? 486 SER G CB   1 
ATOM   11027 O  OG   . SER G 1 279 ? 30.322  -43.072 7.727   1.00 81.10  ? 486 SER G OG   1 
ATOM   11028 N  N    . ARG G 1 280 ? 28.802  -46.305 5.573   1.00 89.92  ? 487 ARG G N    1 
ATOM   11029 C  CA   . ARG G 1 280 ? 28.782  -47.715 6.028   1.00 85.93  ? 487 ARG G CA   1 
ATOM   11030 C  C    . ARG G 1 280 ? 29.931  -47.927 7.012   1.00 87.50  ? 487 ARG G C    1 
ATOM   11031 O  O    . ARG G 1 280 ? 31.063  -47.501 6.708   1.00 81.88  ? 487 ARG G O    1 
ATOM   11032 C  CB   . ARG G 1 280 ? 28.880  -48.645 4.816   1.00 80.94  ? 487 ARG G CB   1 
ATOM   11033 N  N    . CYS G 1 281 ? 29.650  -48.580 8.138   1.00 88.33  ? 488 CYS G N    1 
ATOM   11034 C  CA   . CYS G 1 281 ? 30.680  -48.751 9.191   1.00 88.77  ? 488 CYS G CA   1 
ATOM   11035 C  C    . CYS G 1 281 ? 30.746  -50.204 9.652   1.00 86.73  ? 488 CYS G C    1 
ATOM   11036 O  O    . CYS G 1 281 ? 30.015  -51.042 9.102   1.00 85.47  ? 488 CYS G O    1 
ATOM   11037 C  CB   . CYS G 1 281 ? 30.334  -47.879 10.390  1.00 90.45  ? 488 CYS G CB   1 
ATOM   11038 S  SG   . CYS G 1 281 ? 29.049  -48.575 11.460  1.00 93.79  ? 488 CYS G SG   1 
ATOM   11039 N  N    . THR G 1 282 ? 31.596  -50.475 10.636  1.00 83.04  ? 489 THR G N    1 
ATOM   11040 C  CA   . THR G 1 282 ? 31.688  -51.848 11.182  1.00 86.12  ? 489 THR G CA   1 
ATOM   11041 C  C    . THR G 1 282 ? 31.026  -51.918 12.559  1.00 93.35  ? 489 THR G C    1 
ATOM   11042 O  O    . THR G 1 282 ? 30.895  -50.871 13.220  1.00 91.25  ? 489 THR G O    1 
ATOM   11043 C  CB   . THR G 1 282 ? 33.136  -52.358 11.187  1.00 92.19  ? 489 THR G CB   1 
ATOM   11044 O  OG1  . THR G 1 282 ? 33.085  -53.783 11.229  1.00 97.63  ? 489 THR G OG1  1 
ATOM   11045 C  CG2  . THR G 1 282 ? 33.969  -51.864 12.348  1.00 94.29  ? 489 THR G CG2  1 
ATOM   11046 N  N    . LYS G 1 283 ? 30.610  -53.119 12.954  1.00 95.53  ? 490 LYS G N    1 
ATOM   11047 C  CA   . LYS G 1 283 ? 29.969  -53.326 14.275  1.00 92.95  ? 490 LYS G CA   1 
ATOM   11048 C  C    . LYS G 1 283 ? 30.862  -52.740 15.367  1.00 92.61  ? 490 LYS G C    1 
ATOM   11049 O  O    . LYS G 1 283 ? 30.324  -52.114 16.284  1.00 91.51  ? 490 LYS G O    1 
ATOM   11050 N  N    . GLU G 1 284 ? 32.173  -52.952 15.273  1.00 95.78  ? 491 GLU G N    1 
ATOM   11051 C  CA   . GLU G 1 284 ? 33.042  -52.455 16.334  1.00 92.55  ? 491 GLU G CA   1 
ATOM   11052 C  C    . GLU G 1 284 ? 32.944  -50.939 16.463  1.00 85.41  ? 491 GLU G C    1 
ATOM   11053 O  O    . GLU G 1 284 ? 32.947  -50.404 17.577  1.00 84.47  ? 491 GLU G O    1 
ATOM   11054 N  N    . GLU G 1 285 ? 32.850  -50.231 15.338  1.00 89.74  ? 492 GLU G N    1 
ATOM   11055 C  CA   . GLU G 1 285 ? 32.810  -48.773 15.372  1.00 91.88  ? 492 GLU G CA   1 
ATOM   11056 C  C    . GLU G 1 285 ? 31.447  -48.221 15.775  1.00 94.91  ? 492 GLU G C    1 
ATOM   11057 O  O    . GLU G 1 285 ? 31.347  -47.029 16.096  1.00 92.85  ? 492 GLU G O    1 
ATOM   11058 C  CB   . GLU G 1 285 ? 33.218  -48.193 14.010  1.00 88.86  ? 492 GLU G CB   1 
ATOM   11059 C  CG   . GLU G 1 285 ? 34.653  -48.496 13.591  1.00 88.94  ? 492 GLU G CG   1 
ATOM   11060 C  CD   . GLU G 1 285 ? 34.875  -48.296 12.095  1.00 92.13  ? 492 GLU G CD   1 
ATOM   11061 O  OE1  . GLU G 1 285 ? 33.871  -48.270 11.343  1.00 90.17  ? 492 GLU G OE1  1 
ATOM   11062 O  OE2  . GLU G 1 285 ? 36.046  -48.216 11.666  1.00 91.01  ? 492 GLU G OE2  1 
ATOM   11063 N  N    . ALA G 1 286 ? 30.397  -49.043 15.764  1.00 95.44  ? 493 ALA G N    1 
ATOM   11064 C  CA   . ALA G 1 286 ? 29.088  -48.608 16.233  1.00 88.84  ? 493 ALA G CA   1 
ATOM   11065 C  C    . ALA G 1 286 ? 28.766  -49.081 17.646  1.00 85.18  ? 493 ALA G C    1 
ATOM   11066 O  O    . ALA G 1 286 ? 27.853  -48.529 18.271  1.00 85.40  ? 493 ALA G O    1 
ATOM   11067 C  CB   . ALA G 1 286 ? 27.986  -49.083 15.275  1.00 82.61  ? 493 ALA G CB   1 
ATOM   11068 N  N    . ILE G 1 287 ? 29.489  -50.068 18.175  1.00 82.54  ? 494 ILE G N    1 
ATOM   11069 C  CA   . ILE G 1 287 ? 29.158  -50.596 19.494  1.00 79.28  ? 494 ILE G CA   1 
ATOM   11070 C  C    . ILE G 1 287 ? 30.308  -50.375 20.463  1.00 80.23  ? 494 ILE G C    1 
ATOM   11071 O  O    . ILE G 1 287 ? 30.210  -49.545 21.373  1.00 79.92  ? 494 ILE G O    1 
ATOM   11072 C  CB   . ILE G 1 287 ? 28.786  -52.088 19.427  1.00 74.10  ? 494 ILE G CB   1 
ATOM   11073 C  CG1  . ILE G 1 287 ? 27.523  -52.275 18.585  1.00 72.95  ? 494 ILE G CG1  1 
ATOM   11074 C  CG2  . ILE G 1 287 ? 28.572  -52.635 20.835  1.00 72.58  ? 494 ILE G CG2  1 
ATOM   11075 C  CD1  . ILE G 1 287 ? 27.305  -53.676 18.111  1.00 67.11  ? 494 ILE G CD1  1 
ATOM   11076 N  N    . GLU G 1 288 ? 31.405  -51.116 20.272  1.00 82.11  ? 495 GLU G N    1 
ATOM   11077 C  CA   . GLU G 1 288 ? 32.486  -51.123 21.255  1.00 76.71  ? 495 GLU G CA   1 
ATOM   11078 C  C    . GLU G 1 288 ? 33.249  -49.806 21.274  1.00 76.92  ? 495 GLU G C    1 
ATOM   11079 O  O    . GLU G 1 288 ? 33.841  -49.458 22.301  1.00 71.43  ? 495 GLU G O    1 
ATOM   11080 C  CB   . GLU G 1 288 ? 33.439  -52.289 20.979  1.00 76.46  ? 495 GLU G CB   1 
ATOM   11081 N  N    . HIS G 1 289 ? 33.258  -49.070 20.155  1.00 84.08  ? 496 HIS G N    1 
ATOM   11082 C  CA   . HIS G 1 289 ? 33.892  -47.758 20.093  1.00 82.31  ? 496 HIS G CA   1 
ATOM   11083 C  C    . HIS G 1 289 ? 33.064  -46.667 20.765  1.00 85.38  ? 496 HIS G C    1 
ATOM   11084 O  O    . HIS G 1 289 ? 33.559  -45.545 20.928  1.00 84.87  ? 496 HIS G O    1 
ATOM   11085 N  N    . ASN G 1 290 ? 31.824  -46.969 21.163  1.00 85.44  ? 497 ASN G N    1 
ATOM   11086 C  CA   . ASN G 1 290 ? 30.927  -45.999 21.779  1.00 81.74  ? 497 ASN G CA   1 
ATOM   11087 C  C    . ASN G 1 290 ? 30.683  -46.291 23.257  1.00 76.69  ? 497 ASN G C    1 
ATOM   11088 O  O    . ASN G 1 290 ? 29.748  -45.744 23.852  1.00 74.37  ? 497 ASN G O    1 
ATOM   11089 C  CB   . ASN G 1 290 ? 29.612  -45.943 21.002  1.00 75.40  ? 497 ASN G CB   1 
ATOM   11090 C  CG   . ASN G 1 290 ? 29.817  -45.516 19.567  1.00 78.83  ? 497 ASN G CG   1 
ATOM   11091 O  OD1  . ASN G 1 290 ? 30.568  -44.586 19.300  1.00 78.43  ? 497 ASN G OD1  1 
ATOM   11092 N  ND2  . ASN G 1 290 ? 29.149  -46.184 18.635  1.00 78.39  ? 497 ASN G ND2  1 
ATOM   11093 N  N    . TYR G 1 291 ? 31.514  -47.129 23.865  1.00 70.79  ? 498 TYR G N    1 
ATOM   11094 C  CA   . TYR G 1 291 ? 31.416  -47.376 25.296  1.00 74.42  ? 498 TYR G CA   1 
ATOM   11095 C  C    . TYR G 1 291 ? 31.886  -46.160 26.080  1.00 71.86  ? 498 TYR G C    1 
ATOM   11096 O  O    . TYR G 1 291 ? 31.820  -46.155 27.308  1.00 74.47  ? 498 TYR G O    1 
ATOM   11097 C  CB   . TYR G 1 291 ? 32.234  -48.605 25.705  1.00 78.86  ? 498 TYR G CB   1 
ATOM   11098 C  CG   . TYR G 1 291 ? 31.665  -49.928 25.222  1.00 78.75  ? 498 TYR G CG   1 
ATOM   11099 C  CD1  . TYR G 1 291 ? 30.551  -49.965 24.390  1.00 76.77  ? 498 TYR G CD1  1 
ATOM   11100 C  CD2  . TYR G 1 291 ? 32.244  -51.143 25.597  1.00 76.82  ? 498 TYR G CD2  1 
ATOM   11101 C  CE1  . TYR G 1 291 ? 30.034  -51.174 23.945  1.00 79.94  ? 498 TYR G CE1  1 
ATOM   11102 C  CE2  . TYR G 1 291 ? 31.726  -52.361 25.156  1.00 67.41  ? 498 TYR G CE2  1 
ATOM   11103 C  CZ   . TYR G 1 291 ? 30.627  -52.363 24.331  1.00 72.75  ? 498 TYR G CZ   1 
ATOM   11104 O  OH   . TYR G 1 291 ? 30.095  -53.537 23.880  1.00 74.12  ? 498 TYR G OH   1 
ATOM   11105 N  N    . ARG G 1 301 ? 37.948  -38.888 21.553  1.00 95.64  ? 508 ARG G N    1 
ATOM   11106 C  CA   . ARG G 1 301 ? 37.460  -40.181 22.025  1.00 88.92  ? 508 ARG G CA   1 
ATOM   11107 C  C    . ARG G 1 301 ? 37.063  -40.101 23.498  1.00 88.00  ? 508 ARG G C    1 
ATOM   11108 O  O    . ARG G 1 301 ? 36.166  -40.816 23.944  1.00 85.91  ? 508 ARG G O    1 
ATOM   11109 N  N    . HIS G 1 302 ? 37.745  -39.228 24.249  1.00 88.20  ? 509 HIS G N    1 
ATOM   11110 C  CA   . HIS G 1 302 ? 37.411  -39.034 25.658  1.00 85.96  ? 509 HIS G CA   1 
ATOM   11111 C  C    . HIS G 1 302 ? 36.019  -38.424 25.820  1.00 90.89  ? 509 HIS G C    1 
ATOM   11112 O  O    . HIS G 1 302 ? 35.278  -38.800 26.737  1.00 82.84  ? 509 HIS G O    1 
ATOM   11113 C  CB   . HIS G 1 302 ? 38.470  -38.158 26.331  1.00 76.79  ? 509 HIS G CB   1 
ATOM   11114 N  N    . CYS G 1 303 ? 35.626  -37.521 24.915  1.00 91.72  ? 510 CYS G N    1 
ATOM   11115 C  CA   . CYS G 1 303 ? 34.324  -36.809 25.054  1.00 85.31  ? 510 CYS G CA   1 
ATOM   11116 C  C    . CYS G 1 303 ? 33.191  -37.555 24.339  1.00 81.49  ? 510 CYS G C    1 
ATOM   11117 O  O    . CYS G 1 303 ? 32.040  -37.153 24.533  1.00 77.81  ? 510 CYS G O    1 
ATOM   11118 C  CB   . CYS G 1 303 ? 34.437  -35.408 24.472  1.00 81.45  ? 510 CYS G CB   1 
ATOM   11119 S  SG   . CYS G 1 303 ? 35.815  -34.454 25.155  1.00 103.06 ? 510 CYS G SG   1 
ATOM   11120 N  N    . THR G 1 304 ? 33.493  -38.603 23.570  1.00 76.56  ? 511 THR G N    1 
ATOM   11121 C  CA   . THR G 1 304 ? 32.486  -39.301 22.788  1.00 76.40  ? 511 THR G CA   1 
ATOM   11122 C  C    . THR G 1 304 ? 32.075  -40.579 23.499  1.00 78.03  ? 511 THR G C    1 
ATOM   11123 O  O    . THR G 1 304 ? 32.881  -41.196 24.201  1.00 78.81  ? 511 THR G O    1 
ATOM   11124 C  CB   . THR G 1 304 ? 33.013  -39.639 21.390  1.00 77.71  ? 511 THR G CB   1 
ATOM   11125 O  OG1  . THR G 1 304 ? 33.670  -38.494 20.844  1.00 83.28  ? 511 THR G OG1  1 
ATOM   11126 C  CG2  . THR G 1 304 ? 31.877  -40.053 20.447  1.00 69.52  ? 511 THR G CG2  1 
ATOM   11127 N  N    . ASN G 1 305 ? 30.811  -40.966 23.306  1.00 78.58  ? 512 ASN G N    1 
ATOM   11128 C  CA   . ASN G 1 305 ? 30.224  -42.165 23.897  1.00 74.52  ? 512 ASN G CA   1 
ATOM   11129 C  C    . ASN G 1 305 ? 28.745  -42.227 23.521  1.00 77.09  ? 512 ASN G C    1 
ATOM   11130 O  O    . ASN G 1 305 ? 28.152  -41.251 23.043  1.00 70.89  ? 512 ASN G O    1 
ATOM   11131 C  CB   . ASN G 1 305 ? 30.380  -42.187 25.417  1.00 72.18  ? 512 ASN G CB   1 
ATOM   11132 C  CG   . ASN G 1 305 ? 30.124  -40.839 26.032  1.00 70.94  ? 512 ASN G CG   1 
ATOM   11133 O  OD1  . ASN G 1 305 ? 29.124  -40.182 25.726  1.00 77.40  ? 512 ASN G OD1  1 
ATOM   11134 N  ND2  . ASN G 1 305 ? 31.036  -40.400 26.883  1.00 71.90  ? 512 ASN G ND2  1 
ATOM   11135 N  N    . ALA G 1 306 ? 28.158  -43.378 23.847  1.00 79.18  ? 513 ALA G N    1 
ATOM   11136 C  CA   . ALA G 1 306 ? 26.730  -43.612 23.572  1.00 75.40  ? 513 ALA G CA   1 
ATOM   11137 C  C    . ALA G 1 306 ? 25.860  -42.948 24.628  1.00 73.32  ? 513 ALA G C    1 
ATOM   11138 O  O    . ALA G 1 306 ? 26.129  -43.121 25.818  1.00 63.65  ? 513 ALA G O    1 
ATOM   11139 C  CB   . ALA G 1 306 ? 26.478  -45.089 23.569  1.00 71.36  ? 513 ALA G CB   1 
ATOM   11140 N  N    . TYR G 1 307 ? 24.823  -42.264 24.178  1.00 66.42  ? 514 TYR G N    1 
ATOM   11141 C  CA   . TYR G 1 307 ? 23.882  -41.587 25.065  1.00 67.55  ? 514 TYR G CA   1 
ATOM   11142 C  C    . TYR G 1 307 ? 22.510  -42.247 25.076  1.00 67.51  ? 514 TYR G C    1 
ATOM   11143 O  O    . TYR G 1 307 ? 21.978  -42.590 26.146  1.00 66.11  ? 514 TYR G O    1 
ATOM   11144 C  CB   . TYR G 1 307 ? 23.749  -40.117 24.645  1.00 63.80  ? 514 TYR G CB   1 
ATOM   11145 C  CG   . TYR G 1 307 ? 22.789  -39.290 25.483  1.00 61.96  ? 514 TYR G CG   1 
ATOM   11146 C  CD1  . TYR G 1 307 ? 22.777  -39.392 26.868  1.00 62.25  ? 514 TYR G CD1  1 
ATOM   11147 C  CD2  . TYR G 1 307 ? 21.920  -38.392 24.885  1.00 58.45  ? 514 TYR G CD2  1 
ATOM   11148 C  CE1  . TYR G 1 307 ? 21.914  -38.636 27.626  1.00 61.26  ? 514 TYR G CE1  1 
ATOM   11149 C  CE2  . TYR G 1 307 ? 21.061  -37.630 25.630  1.00 58.51  ? 514 TYR G CE2  1 
ATOM   11150 C  CZ   . TYR G 1 307 ? 21.057  -37.756 26.998  1.00 63.47  ? 514 TYR G CZ   1 
ATOM   11151 O  OH   . TYR G 1 307 ? 20.189  -36.992 27.743  1.00 69.02  ? 514 TYR G OH   1 
ATOM   11152 N  N    . MET G 1 308 ? 21.918  -42.424 23.903  1.00 65.79  ? 515 MET G N    1 
ATOM   11153 C  CA   . MET G 1 308 ? 20.613  -43.042 23.753  1.00 63.46  ? 515 MET G CA   1 
ATOM   11154 C  C    . MET G 1 308 ? 20.756  -44.277 22.868  1.00 68.56  ? 515 MET G C    1 
ATOM   11155 O  O    . MET G 1 308 ? 21.308  -44.194 21.762  1.00 66.99  ? 515 MET G O    1 
ATOM   11156 C  CB   . MET G 1 308 ? 19.628  -42.037 23.156  1.00 63.06  ? 515 MET G CB   1 
ATOM   11157 C  CG   . MET G 1 308 ? 18.223  -42.544 22.976  1.00 68.70  ? 515 MET G CG   1 
ATOM   11158 S  SD   . MET G 1 308 ? 17.060  -41.171 22.768  1.00 68.14  ? 515 MET G SD   1 
ATOM   11159 C  CE   . MET G 1 308 ? 15.582  -42.079 22.322  1.00 67.28  ? 515 MET G CE   1 
ATOM   11160 N  N    . LEU G 1 309 ? 20.254  -45.412 23.362  1.00 67.01  ? 516 LEU G N    1 
ATOM   11161 C  CA   . LEU G 1 309 ? 20.289  -46.691 22.613  1.00 59.25  ? 516 LEU G CA   1 
ATOM   11162 C  C    . LEU G 1 309 ? 18.860  -47.072 22.256  1.00 65.67  ? 516 LEU G C    1 
ATOM   11163 O  O    . LEU G 1 309 ? 17.980  -46.888 23.098  1.00 65.94  ? 516 LEU G O    1 
ATOM   11164 C  CB   . LEU G 1 309 ? 20.880  -47.770 23.515  1.00 56.67  ? 516 LEU G CB   1 
ATOM   11165 C  CG   . LEU G 1 309 ? 22.244  -47.474 24.122  1.00 56.84  ? 516 LEU G CG   1 
ATOM   11166 C  CD1  . LEU G 1 309 ? 22.573  -48.490 25.201  1.00 60.72  ? 516 LEU G CD1  1 
ATOM   11167 C  CD2  . LEU G 1 309 ? 23.309  -47.484 23.046  1.00 64.38  ? 516 LEU G CD2  1 
ATOM   11168 N  N    . VAL G 1 310 ? 18.646  -47.584 21.050  1.00 63.80  ? 517 VAL G N    1 
ATOM   11169 C  CA   . VAL G 1 310 ? 17.292  -48.048 20.643  1.00 64.05  ? 517 VAL G CA   1 
ATOM   11170 C  C    . VAL G 1 310 ? 17.374  -49.544 20.367  1.00 72.58  ? 517 VAL G C    1 
ATOM   11171 O  O    . VAL G 1 310 ? 18.189  -49.940 19.524  1.00 73.25  ? 517 VAL G O    1 
ATOM   11172 C  CB   . VAL G 1 310 ? 16.758  -47.266 19.434  1.00 67.76  ? 517 VAL G CB   1 
ATOM   11173 C  CG1  . VAL G 1 310 ? 15.511  -47.901 18.840  1.00 59.89  ? 517 VAL G CG1  1 
ATOM   11174 C  CG2  . VAL G 1 310 ? 16.501  -45.813 19.792  1.00 66.73  ? 517 VAL G CG2  1 
ATOM   11175 N  N    . TYR G 1 311 ? 16.583  -50.334 21.089  1.00 69.82  ? 518 TYR G N    1 
ATOM   11176 C  CA   . TYR G 1 311 ? 16.559  -51.803 20.896  1.00 69.49  ? 518 TYR G CA   1 
ATOM   11177 C  C    . TYR G 1 311 ? 15.175  -52.220 20.392  1.00 68.71  ? 518 TYR G C    1 
ATOM   11178 O  O    . TYR G 1 311 ? 14.206  -51.489 20.614  1.00 66.96  ? 518 TYR G O    1 
ATOM   11179 C  CB   . TYR G 1 311 ? 16.890  -52.509 22.207  1.00 66.42  ? 518 TYR G CB   1 
ATOM   11180 C  CG   . TYR G 1 311 ? 18.341  -52.545 22.609  1.00 73.32  ? 518 TYR G CG   1 
ATOM   11181 C  CD1  . TYR G 1 311 ? 18.948  -51.453 23.203  1.00 73.50  ? 518 TYR G CD1  1 
ATOM   11182 C  CD2  . TYR G 1 311 ? 19.093  -53.693 22.447  1.00 75.80  ? 518 TYR G CD2  1 
ATOM   11183 C  CE1  . TYR G 1 311 ? 20.275  -51.489 23.595  1.00 71.56  ? 518 TYR G CE1  1 
ATOM   11184 C  CE2  . TYR G 1 311 ? 20.422  -53.745 22.830  1.00 75.66  ? 518 TYR G CE2  1 
ATOM   11185 C  CZ   . TYR G 1 311 ? 21.015  -52.640 23.409  1.00 75.02  ? 518 TYR G CZ   1 
ATOM   11186 O  OH   . TYR G 1 311 ? 22.322  -52.684 23.792  1.00 77.29  ? 518 TYR G OH   1 
ATOM   11187 N  N    . ILE G 1 312 ? 15.091  -53.358 19.710  1.00 69.76  ? 519 ILE G N    1 
ATOM   11188 C  CA   . ILE G 1 312 ? 13.794  -53.865 19.167  1.00 73.02  ? 519 ILE G CA   1 
ATOM   11189 C  C    . ILE G 1 312 ? 13.631  -55.344 19.543  1.00 70.80  ? 519 ILE G C    1 
ATOM   11190 O  O    . ILE G 1 312 ? 14.596  -56.097 19.375  1.00 70.43  ? 519 ILE G O    1 
ATOM   11191 C  CB   . ILE G 1 312 ? 13.697  -53.636 17.644  1.00 73.69  ? 519 ILE G CB   1 
ATOM   11192 C  CG1  . ILE G 1 312 ? 13.549  -52.158 17.283  1.00 64.73  ? 519 ILE G CG1  1 
ATOM   11193 C  CG2  . ILE G 1 312 ? 12.577  -54.462 17.038  1.00 69.27  ? 519 ILE G CG2  1 
ATOM   11194 C  CD1  . ILE G 1 312 ? 13.675  -51.882 15.809  1.00 60.00  ? 519 ILE G CD1  1 
ATOM   11195 N  N    . ARG G 1 313 ? 12.457  -55.724 20.051  1.00 70.06  ? 520 ARG G N    1 
ATOM   11196 C  CA   . ARG G 1 313 ? 12.171  -57.138 20.413  1.00 75.54  ? 520 ARG G CA   1 
ATOM   11197 C  C    . ARG G 1 313 ? 12.130  -57.988 19.146  1.00 71.93  ? 520 ARG G C    1 
ATOM   11198 O  O    . ARG G 1 313 ? 11.390  -57.622 18.222  1.00 70.23  ? 520 ARG G O    1 
ATOM   11199 C  CB   . ARG G 1 313 ? 10.838  -57.229 21.157  1.00 70.37  ? 520 ARG G CB   1 
ATOM   11200 C  CG   . ARG G 1 313 ? 10.637  -58.506 21.956  1.00 72.65  ? 520 ARG G CG   1 
ATOM   11201 C  CD   . ARG G 1 313 ? 9.280   -58.451 22.625  1.00 67.77  ? 520 ARG G CD   1 
ATOM   11202 N  NE   . ARG G 1 313 ? 9.249   -59.154 23.896  1.00 69.02  ? 520 ARG G NE   1 
ATOM   11203 C  CZ   . ARG G 1 313 ? 8.193   -59.224 24.695  1.00 71.24  ? 520 ARG G CZ   1 
ATOM   11204 N  NH1  . ARG G 1 313 ? 7.061   -58.634 24.356  1.00 73.07  ? 520 ARG G NH1  1 
ATOM   11205 N  NH2  . ARG G 1 313 ? 8.267   -59.896 25.829  1.00 70.18  ? 520 ARG G NH2  1 
ATOM   11206 N  N    . GLU G 1 314 ? 12.869  -59.096 19.128  1.00 72.08  ? 521 GLU G N    1 
ATOM   11207 C  CA   . GLU G 1 314 ? 12.965  -59.923 17.896  1.00 72.58  ? 521 GLU G CA   1 
ATOM   11208 C  C    . GLU G 1 314 ? 11.582  -60.451 17.497  1.00 70.22  ? 521 GLU G C    1 
ATOM   11209 O  O    . GLU G 1 314 ? 11.353  -60.603 16.290  1.00 74.40  ? 521 GLU G O    1 
ATOM   11210 C  CB   . GLU G 1 314 ? 13.995  -61.041 18.063  1.00 70.59  ? 521 GLU G CB   1 
ATOM   11211 C  CG   . GLU G 1 314 ? 13.949  -61.749 19.397  1.00 74.92  ? 521 GLU G CG   1 
ATOM   11212 C  CD   . GLU G 1 314 ? 14.846  -62.972 19.458  1.00 82.02  ? 521 GLU G CD   1 
ATOM   11213 O  OE1  . GLU G 1 314 ? 16.030  -62.854 19.088  1.00 82.60  ? 521 GLU G OE1  1 
ATOM   11214 O  OE2  . GLU G 1 314 ? 14.356  -64.038 19.873  1.00 89.24  ? 521 GLU G OE2  1 
ATOM   11215 N  N    . SER G 1 315 ? 10.700  -60.695 18.464  1.00 68.70  ? 522 SER G N    1 
ATOM   11216 C  CA   . SER G 1 315 ? 9.365   -61.163 18.122  1.00 70.37  ? 522 SER G CA   1 
ATOM   11217 C  C    . SER G 1 315 ? 8.682   -60.228 17.135  1.00 71.22  ? 522 SER G C    1 
ATOM   11218 O  O    . SER G 1 315 ? 7.935   -60.683 16.263  1.00 75.53  ? 522 SER G O    1 
ATOM   11219 C  CB   . SER G 1 315 ? 8.520   -61.317 19.388  1.00 74.64  ? 522 SER G CB   1 
ATOM   11220 O  OG   . SER G 1 315 ? 7.148   -61.051 19.121  1.00 75.85  ? 522 SER G OG   1 
ATOM   11221 N  N    . LYS G 1 316 ? 8.935   -58.919 17.236  1.00 70.86  ? 523 LYS G N    1 
ATOM   11222 C  CA   . LYS G 1 316 ? 8.250   -57.958 16.373  1.00 70.54  ? 523 LYS G CA   1 
ATOM   11223 C  C    . LYS G 1 316 ? 9.203   -57.175 15.476  1.00 70.56  ? 523 LYS G C    1 
ATOM   11224 O  O    . LYS G 1 316 ? 8.786   -56.191 14.851  1.00 70.61  ? 523 LYS G O    1 
ATOM   11225 C  CB   . LYS G 1 316 ? 7.389   -57.006 17.210  1.00 66.56  ? 523 LYS G CB   1 
ATOM   11226 C  CG   . LYS G 1 316 ? 6.116   -57.659 17.742  1.00 74.81  ? 523 LYS G CG   1 
ATOM   11227 N  N    . LEU G 1 317 ? 10.427  -57.659 15.290  1.00 71.86  ? 524 LEU G N    1 
ATOM   11228 C  CA   . LEU G 1 317 ? 11.390  -56.979 14.381  1.00 73.79  ? 524 LEU G CA   1 
ATOM   11229 C  C    . LEU G 1 317 ? 10.878  -56.978 12.940  1.00 75.17  ? 524 LEU G C    1 
ATOM   11230 O  O    . LEU G 1 317 ? 11.284  -56.089 12.191  1.00 76.94  ? 524 LEU G O    1 
ATOM   11231 C  CB   . LEU G 1 317 ? 12.745  -57.683 14.467  1.00 67.23  ? 524 LEU G CB   1 
ATOM   11232 N  N    . SER G 1 318 ? 10.037  -57.942 12.573  1.00 77.96  ? 525 SER G N    1 
ATOM   11233 C  CA   . SER G 1 318 ? 9.562   -58.058 11.172  1.00 76.78  ? 525 SER G CA   1 
ATOM   11234 C  C    . SER G 1 318 ? 8.371   -57.130 10.931  1.00 76.69  ? 525 SER G C    1 
ATOM   11235 O  O    . SER G 1 318 ? 8.151   -56.760 9.768   1.00 79.19  ? 525 SER G O    1 
ATOM   11236 C  CB   . SER G 1 318 ? 9.230   -59.484 10.841  1.00 77.35  ? 525 SER G CB   1 
ATOM   11237 O  OG   . SER G 1 318 ? 7.924   -59.821 11.284  1.00 86.31  ? 525 SER G OG   1 
ATOM   11238 N  N    . GLU G 1 319 ? 7.633   -56.784 11.982  1.00 78.15  ? 526 GLU G N    1 
ATOM   11239 C  CA   . GLU G 1 319 ? 6.518   -55.819 11.828  1.00 79.06  ? 526 GLU G CA   1 
ATOM   11240 C  C    . GLU G 1 319 ? 7.075   -54.400 11.853  1.00 80.48  ? 526 GLU G C    1 
ATOM   11241 O  O    . GLU G 1 319 ? 6.617   -53.579 11.060  1.00 80.47  ? 526 GLU G O    1 
ATOM   11242 C  CB   . GLU G 1 319 ? 5.499   -55.994 12.948  1.00 81.69  ? 526 GLU G CB   1 
ATOM   11243 C  CG   . GLU G 1 319 ? 4.126   -55.457 12.595  1.00 78.97  ? 526 GLU G CG   1 
ATOM   11244 C  CD   . GLU G 1 319 ? 3.072   -55.622 13.676  1.00 89.66  ? 526 GLU G CD   1 
ATOM   11245 O  OE1  . GLU G 1 319 ? 1.973   -55.063 13.511  1.00 95.63  ? 526 GLU G OE1  1 
ATOM   11246 O  OE2  . GLU G 1 319 ? 3.349   -56.311 14.678  1.00 94.88  ? 526 GLU G OE2  1 
ATOM   11247 N  N    . VAL G 1 320 ? 8.021   -54.122 12.743  1.00 80.64  ? 527 VAL G N    1 
ATOM   11248 C  CA   . VAL G 1 320 ? 8.509   -52.718 12.874  1.00 86.32  ? 527 VAL G CA   1 
ATOM   11249 C  C    . VAL G 1 320 ? 9.545   -52.438 11.782  1.00 84.95  ? 527 VAL G C    1 
ATOM   11250 O  O    . VAL G 1 320 ? 9.581   -51.301 11.324  1.00 80.58  ? 527 VAL G O    1 
ATOM   11251 C  CB   . VAL G 1 320 ? 9.034   -52.424 14.294  1.00 83.46  ? 527 VAL G CB   1 
ATOM   11252 C  CG1  . VAL G 1 320 ? 7.994   -52.738 15.355  1.00 79.71  ? 527 VAL G CG1  1 
ATOM   11253 C  CG2  . VAL G 1 320 ? 10.332  -53.139 14.600  1.00 78.99  ? 527 VAL G CG2  1 
ATOM   11254 N  N    . LEU G 1 321 ? 10.351  -53.432 11.403  1.00 82.65  ? 528 LEU G N    1 
ATOM   11255 C  CA   . LEU G 1 321 ? 11.338  -53.278 10.305  1.00 79.90  ? 528 LEU G CA   1 
ATOM   11256 C  C    . LEU G 1 321 ? 10.646  -53.731 9.023   1.00 86.42  ? 528 LEU G C    1 
ATOM   11257 O  O    . LEU G 1 321 ? 11.257  -54.515 8.279   1.00 87.06  ? 528 LEU G O    1 
ATOM   11258 N  N    . GLN G 1 322 ? 9.425   -53.266 8.765   1.00 87.48  ? 529 GLN G N    1 
ATOM   11259 C  CA   . GLN G 1 322 ? 8.690   -53.740 7.568   1.00 81.91  ? 529 GLN G CA   1 
ATOM   11260 C  C    . GLN G 1 322 ? 9.224   -53.027 6.323   1.00 83.31  ? 529 GLN G C    1 
ATOM   11261 O  O    . GLN G 1 322 ? 10.342  -52.504 6.363   1.00 88.80  ? 529 GLN G O    1 
ATOM   11262 C  CB   . GLN G 1 322 ? 7.182   -53.562 7.747   1.00 82.31  ? 529 GLN G CB   1 
ATOM   11263 C  CG   . GLN G 1 322 ? 6.721   -52.152 8.075   1.00 87.47  ? 529 GLN G CG   1 
ATOM   11264 C  CD   . GLN G 1 322 ? 5.222   -52.136 8.241   1.00 88.16  ? 529 GLN G CD   1 
ATOM   11265 O  OE1  . GLN G 1 322 ? 4.698   -52.050 9.348   1.00 91.16  ? 529 GLN G OE1  1 
ATOM   11266 N  NE2  . GLN G 1 322 ? 4.512   -52.244 7.131   1.00 81.71  ? 529 GLN G NE2  1 
ATOM   11267 N  N    . ALA G 1 323 ? 8.454   -53.023 5.240   1.00 85.21  ? 530 ALA G N    1 
ATOM   11268 C  CA   . ALA G 1 323 ? 8.948   -52.423 3.982   1.00 83.48  ? 530 ALA G CA   1 
ATOM   11269 C  C    . ALA G 1 323 ? 7.823   -51.648 3.294   1.00 80.95  ? 530 ALA G C    1 
ATOM   11270 O  O    . ALA G 1 323 ? 8.164   -50.801 2.450   1.00 82.69  ? 530 ALA G O    1 
ATOM   11271 C  CB   . ALA G 1 323 ? 9.506   -53.504 3.099   1.00 81.52  ? 530 ALA G CB   1 
ATOM   11272 N  N    . MET H 2 1   ? 0.628   -34.339 49.506  1.00 49.07  ? 1   MET H N    1 
ATOM   11273 C  CA   . MET H 2 1   ? 0.749   -35.708 49.033  1.00 62.73  ? 1   MET H CA   1 
ATOM   11274 C  C    . MET H 2 1   ? 2.196   -36.018 48.646  1.00 58.07  ? 1   MET H C    1 
ATOM   11275 O  O    . MET H 2 1   ? 2.916   -35.177 48.099  1.00 54.61  ? 1   MET H O    1 
ATOM   11276 C  CB   . MET H 2 1   ? -0.193  -35.968 47.849  1.00 50.65  ? 1   MET H CB   1 
ATOM   11277 C  CG   . MET H 2 1   ? 0.218   -35.304 46.587  1.00 56.19  ? 1   MET H CG   1 
ATOM   11278 S  SD   . MET H 2 1   ? -0.881  -35.701 45.230  1.00 63.06  ? 1   MET H SD   1 
ATOM   11279 C  CE   . MET H 2 1   ? -0.284  -34.574 43.974  1.00 56.86  ? 1   MET H CE   1 
ATOM   11280 N  N    . GLN H 2 2   ? 2.613   -37.238 48.941  1.00 53.77  ? 2   GLN H N    1 
ATOM   11281 C  CA   . GLN H 2 2   ? 4.006   -37.629 48.835  1.00 53.29  ? 2   GLN H CA   1 
ATOM   11282 C  C    . GLN H 2 2   ? 4.204   -38.353 47.511  1.00 53.70  ? 2   GLN H C    1 
ATOM   11283 O  O    . GLN H 2 2   ? 3.631   -39.429 47.305  1.00 57.11  ? 2   GLN H O    1 
ATOM   11284 C  CB   . GLN H 2 2   ? 4.398   -38.515 50.009  1.00 52.37  ? 2   GLN H CB   1 
ATOM   11285 C  CG   . GLN H 2 2   ? 5.759   -39.131 49.841  1.00 54.61  ? 2   GLN H CG   1 
ATOM   11286 C  CD   . GLN H 2 2   ? 6.061   -40.104 50.920  1.00 55.62  ? 2   GLN H CD   1 
ATOM   11287 O  OE1  . GLN H 2 2   ? 5.742   -41.287 50.803  1.00 60.81  ? 2   GLN H OE1  1 
ATOM   11288 N  NE2  . GLN H 2 2   ? 6.648   -39.618 52.005  1.00 54.72  ? 2   GLN H NE2  1 
ATOM   11289 N  N    . ILE H 2 3   ? 4.993   -37.758 46.618  1.00 47.82  ? 3   ILE H N    1 
ATOM   11290 C  CA   . ILE H 2 3   ? 5.361   -38.395 45.364  1.00 49.24  ? 3   ILE H CA   1 
ATOM   11291 C  C    . ILE H 2 3   ? 6.791   -38.912 45.435  1.00 48.27  ? 3   ILE H C    1 
ATOM   11292 O  O    . ILE H 2 3   ? 7.528   -38.661 46.384  1.00 50.69  ? 3   ILE H O    1 
ATOM   11293 C  CB   . ILE H 2 3   ? 5.192   -37.461 44.162  1.00 47.63  ? 3   ILE H CB   1 
ATOM   11294 C  CG1  . ILE H 2 3   ? 6.221   -36.331 44.224  1.00 51.66  ? 3   ILE H CG1  1 
ATOM   11295 C  CG2  . ILE H 2 3   ? 3.751   -36.985 44.093  1.00 55.36  ? 3   ILE H CG2  1 
ATOM   11296 C  CD1  . ILE H 2 3   ? 6.211   -35.433 43.023  1.00 46.21  ? 3   ILE H CD1  1 
ATOM   11297 N  N    . PHE H 2 4   ? 7.163   -39.680 44.428  1.00 48.67  ? 4   PHE H N    1 
ATOM   11298 C  CA   . PHE H 2 4   ? 8.549   -40.185 44.379  1.00 50.79  ? 4   PHE H CA   1 
ATOM   11299 C  C    . PHE H 2 4   ? 9.273   -39.535 43.208  1.00 49.68  ? 4   PHE H C    1 
ATOM   11300 O  O    . PHE H 2 4   ? 8.675   -39.372 42.150  1.00 48.47  ? 4   PHE H O    1 
ATOM   11301 C  CB   . PHE H 2 4   ? 8.553   -41.708 44.287  1.00 52.75  ? 4   PHE H CB   1 
ATOM   11302 C  CG   . PHE H 2 4   ? 8.002   -42.421 45.491  1.00 54.44  ? 4   PHE H CG   1 
ATOM   11303 C  CD1  . PHE H 2 4   ? 8.523   -42.192 46.753  1.00 58.87  ? 4   PHE H CD1  1 
ATOM   11304 C  CD2  . PHE H 2 4   ? 6.966   -43.328 45.359  1.00 56.41  ? 4   PHE H CD2  1 
ATOM   11305 C  CE1  . PHE H 2 4   ? 8.015   -42.855 47.858  1.00 61.94  ? 4   PHE H CE1  1 
ATOM   11306 C  CE2  . PHE H 2 4   ? 6.458   -43.987 46.464  1.00 55.43  ? 4   PHE H CE2  1 
ATOM   11307 C  CZ   . PHE H 2 4   ? 6.982   -43.749 47.711  1.00 60.93  ? 4   PHE H CZ   1 
ATOM   11308 N  N    . VAL H 2 5   ? 10.506  -39.103 43.437  1.00 50.57  ? 5   VAL H N    1 
ATOM   11309 C  CA   . VAL H 2 5   ? 11.335  -38.567 42.327  1.00 47.57  ? 5   VAL H CA   1 
ATOM   11310 C  C    . VAL H 2 5   ? 12.575  -39.452 42.252  1.00 50.03  ? 5   VAL H C    1 
ATOM   11311 O  O    . VAL H 2 5   ? 13.206  -39.673 43.281  1.00 53.78  ? 5   VAL H O    1 
ATOM   11312 C  CB   . VAL H 2 5   ? 11.687  -37.079 42.500  1.00 49.00  ? 5   VAL H CB   1 
ATOM   11313 C  CG1  . VAL H 2 5   ? 12.657  -36.586 41.439  1.00 44.99  ? 5   VAL H CG1  1 
ATOM   11314 C  CG2  . VAL H 2 5   ? 10.449  -36.200 42.538  1.00 45.91  ? 5   VAL H CG2  1 
ATOM   11315 N  N    . LYS H 2 6   ? 12.859  -39.991 41.073  1.00 50.91  ? 6   LYS H N    1 
ATOM   11316 C  CA   . LYS H 2 6   ? 14.081  -40.806 40.877  1.00 58.63  ? 6   LYS H CA   1 
ATOM   11317 C  C    . LYS H 2 6   ? 15.195  -39.857 40.453  1.00 52.55  ? 6   LYS H C    1 
ATOM   11318 O  O    . LYS H 2 6   ? 15.056  -39.238 39.398  1.00 53.33  ? 6   LYS H O    1 
ATOM   11319 C  CB   . LYS H 2 6   ? 13.826  -41.914 39.853  1.00 55.52  ? 6   LYS H CB   1 
ATOM   11320 N  N    . THR H 2 7   ? 16.265  -39.785 41.234  1.00 57.74  ? 7   THR H N    1 
ATOM   11321 C  CA   . THR H 2 7   ? 17.349  -38.803 40.981  1.00 58.76  ? 7   THR H CA   1 
ATOM   11322 C  C    . THR H 2 7   ? 18.315  -39.267 39.887  1.00 63.66  ? 7   THR H C    1 
ATOM   11323 O  O    . THR H 2 7   ? 18.087  -40.328 39.288  1.00 62.67  ? 7   THR H O    1 
ATOM   11324 C  CB   . THR H 2 7   ? 18.081  -38.513 42.295  1.00 61.62  ? 7   THR H CB   1 
ATOM   11325 O  OG1  . THR H 2 7   ? 18.788  -39.686 42.697  1.00 64.66  ? 7   THR H OG1  1 
ATOM   11326 C  CG2  . THR H 2 7   ? 17.133  -38.097 43.394  1.00 56.04  ? 7   THR H CG2  1 
ATOM   11327 N  N    . LEU H 2 8   ? 19.372  -38.491 39.659  1.00 65.24  ? 8   LEU H N    1 
ATOM   11328 C  CA   . LEU H 2 8   ? 20.369  -38.829 38.614  1.00 65.20  ? 8   LEU H CA   1 
ATOM   11329 C  C    . LEU H 2 8   ? 21.224  -40.008 39.076  1.00 66.53  ? 8   LEU H C    1 
ATOM   11330 O  O    . LEU H 2 8   ? 21.803  -40.670 38.209  1.00 67.30  ? 8   LEU H O    1 
ATOM   11331 C  CB   . LEU H 2 8   ? 21.214  -37.585 38.350  1.00 62.61  ? 8   LEU H CB   1 
ATOM   11332 C  CG   . LEU H 2 8   ? 20.439  -36.272 38.298  1.00 66.42  ? 8   LEU H CG   1 
ATOM   11333 C  CD1  . LEU H 2 8   ? 21.361  -35.092 38.547  1.00 69.60  ? 8   LEU H CD1  1 
ATOM   11334 C  CD2  . LEU H 2 8   ? 19.722  -36.124 36.968  1.00 60.09  ? 8   LEU H CD2  1 
ATOM   11335 N  N    . THR H 2 9   ? 21.270  -40.266 40.384  1.00 68.48  ? 9   THR H N    1 
ATOM   11336 C  CA   . THR H 2 9   ? 22.044  -41.399 40.953  1.00 66.94  ? 9   THR H CA   1 
ATOM   11337 C  C    . THR H 2 9   ? 21.264  -42.703 40.799  1.00 65.87  ? 9   THR H C    1 
ATOM   11338 O  O    . THR H 2 9   ? 21.878  -43.763 40.937  1.00 68.94  ? 9   THR H O    1 
ATOM   11339 C  CB   . THR H 2 9   ? 22.361  -41.143 42.429  1.00 69.12  ? 9   THR H CB   1 
ATOM   11340 O  OG1  . THR H 2 9   ? 21.180  -41.347 43.204  1.00 68.29  ? 9   THR H OG1  1 
ATOM   11341 C  CG2  . THR H 2 9   ? 22.896  -39.750 42.679  1.00 63.52  ? 9   THR H CG2  1 
ATOM   11342 N  N    . GLY H 2 10  ? 19.965  -42.616 40.530  1.00 68.24  ? 10  GLY H N    1 
ATOM   11343 C  CA   . GLY H 2 10  ? 19.123  -43.817 40.419  1.00 65.77  ? 10  GLY H CA   1 
ATOM   11344 C  C    . GLY H 2 10  ? 18.323  -44.050 41.683  1.00 63.64  ? 10  GLY H C    1 
ATOM   11345 O  O    . GLY H 2 10  ? 17.450  -44.924 41.668  1.00 71.33  ? 10  GLY H O    1 
ATOM   11346 N  N    . LYS H 2 11  ? 18.608  -43.291 42.737  1.00 64.50  ? 11  LYS H N    1 
ATOM   11347 C  CA   . LYS H 2 11  ? 17.925  -43.493 44.034  1.00 59.54  ? 11  LYS H CA   1 
ATOM   11348 C  C    . LYS H 2 11  ? 16.585  -42.762 44.041  1.00 60.33  ? 11  LYS H C    1 
ATOM   11349 O  O    . LYS H 2 11  ? 16.472  -41.715 43.391  1.00 60.15  ? 11  LYS H O    1 
ATOM   11350 C  CB   . LYS H 2 11  ? 18.817  -43.007 45.173  1.00 48.44  ? 11  LYS H CB   1 
ATOM   11351 N  N    . THR H 2 12  ? 15.619  -43.306 44.772  1.00 56.62  ? 12  THR H N    1 
ATOM   11352 C  CA   . THR H 2 12  ? 14.274  -42.694 44.847  1.00 57.19  ? 12  THR H CA   1 
ATOM   11353 C  C    . THR H 2 12  ? 14.208  -41.776 46.063  1.00 57.77  ? 12  THR H C    1 
ATOM   11354 O  O    . THR H 2 12  ? 14.613  -42.209 47.149  1.00 55.04  ? 12  THR H O    1 
ATOM   11355 C  CB   . THR H 2 12  ? 13.174  -43.760 44.871  1.00 54.59  ? 12  THR H CB   1 
ATOM   11356 O  OG1  . THR H 2 12  ? 13.188  -44.441 43.618  1.00 54.71  ? 12  THR H OG1  1 
ATOM   11357 C  CG2  . THR H 2 12  ? 11.801  -43.179 45.112  1.00 56.89  ? 12  THR H CG2  1 
ATOM   11358 N  N    . ILE H 2 13  ? 13.766  -40.540 45.854  1.00 52.54  ? 13  ILE H N    1 
ATOM   11359 C  CA   . ILE H 2 13  ? 13.561  -39.612 46.993  1.00 52.13  ? 13  ILE H CA   1 
ATOM   11360 C  C    . ILE H 2 13  ? 12.069  -39.299 47.089  1.00 52.66  ? 13  ILE H C    1 
ATOM   11361 O  O    . ILE H 2 13  ? 11.361  -39.434 46.092  1.00 49.20  ? 13  ILE H O    1 
ATOM   11362 C  CB   . ILE H 2 13  ? 14.420  -38.337 46.866  1.00 55.18  ? 13  ILE H CB   1 
ATOM   11363 C  CG1  . ILE H 2 13  ? 14.118  -37.543 45.594  1.00 52.24  ? 13  ILE H CG1  1 
ATOM   11364 C  CG2  . ILE H 2 13  ? 15.898  -38.665 46.993  1.00 52.87  ? 13  ILE H CG2  1 
ATOM   11365 C  CD1  . ILE H 2 13  ? 13.997  -36.061 45.817  1.00 51.13  ? 13  ILE H CD1  1 
ATOM   11366 N  N    . THR H 2 14  ? 11.619  -38.927 48.279  1.00 57.06  ? 14  THR H N    1 
ATOM   11367 C  CA   . THR H 2 14  ? 10.210  -38.532 48.483  1.00 52.88  ? 14  THR H CA   1 
ATOM   11368 C  C    . THR H 2 14  ? 10.096  -37.018 48.313  1.00 54.84  ? 14  THR H C    1 
ATOM   11369 O  O    . THR H 2 14  ? 11.073  -36.332 48.594  1.00 52.84  ? 14  THR H O    1 
ATOM   11370 C  CB   . THR H 2 14  ? 9.740   -38.997 49.862  1.00 56.21  ? 14  THR H CB   1 
ATOM   11371 O  OG1  . THR H 2 14  ? 10.515  -38.338 50.862  1.00 59.27  ? 14  THR H OG1  1 
ATOM   11372 C  CG2  . THR H 2 14  ? 9.839   -40.495 50.034  1.00 58.48  ? 14  THR H CG2  1 
ATOM   11373 N  N    . LEU H 2 15  ? 8.955   -36.527 47.839  1.00 54.70  ? 15  LEU H N    1 
ATOM   11374 C  CA   . LEU H 2 15  ? 8.748   -35.058 47.746  1.00 53.89  ? 15  LEU H CA   1 
ATOM   11375 C  C    . LEU H 2 15  ? 7.337   -34.710 48.216  1.00 58.51  ? 15  LEU H C    1 
ATOM   11376 O  O    . LEU H 2 15  ? 6.375   -35.275 47.676  1.00 53.23  ? 15  LEU H O    1 
ATOM   11377 C  CB   . LEU H 2 15  ? 8.992   -34.577 46.316  1.00 53.90  ? 15  LEU H CB   1 
ATOM   11378 C  CG   . LEU H 2 15  ? 9.603   -33.188 46.184  1.00 55.94  ? 15  LEU H CG   1 
ATOM   11379 C  CD1  . LEU H 2 15  ? 11.041  -33.178 46.670  1.00 45.77  ? 15  LEU H CD1  1 
ATOM   11380 C  CD2  . LEU H 2 15  ? 9.530   -32.724 44.743  1.00 50.50  ? 15  LEU H CD2  1 
ATOM   11381 N  N    . GLU H 2 16  ? 7.242   -33.812 49.195  1.00 54.83  ? 16  GLU H N    1 
ATOM   11382 C  CA   . GLU H 2 16  ? 5.920   -33.370 49.693  1.00 52.43  ? 16  GLU H CA   1 
ATOM   11383 C  C    . GLU H 2 16  ? 5.426   -32.246 48.799  1.00 57.99  ? 16  GLU H C    1 
ATOM   11384 O  O    . GLU H 2 16  ? 5.910   -31.132 48.955  1.00 61.38  ? 16  GLU H O    1 
ATOM   11385 C  CB   . GLU H 2 16  ? 5.990   -32.976 51.161  1.00 54.77  ? 16  GLU H CB   1 
ATOM   11386 C  CG   . GLU H 2 16  ? 4.660   -33.104 51.872  1.00 61.41  ? 16  GLU H CG   1 
ATOM   11387 C  CD   . GLU H 2 16  ? 4.014   -34.474 51.783  1.00 66.54  ? 16  GLU H CD   1 
ATOM   11388 O  OE1  . GLU H 2 16  ? 4.722   -35.482 51.972  1.00 64.54  ? 16  GLU H OE1  1 
ATOM   11389 O  OE2  . GLU H 2 16  ? 2.801   -34.525 51.545  1.00 70.26  ? 16  GLU H OE2  1 
ATOM   11390 N  N    . VAL H 2 17  ? 4.488   -32.549 47.919  1.00 50.99  ? 17  VAL H N    1 
ATOM   11391 C  CA   . VAL H 2 17  ? 3.947   -31.622 46.951  1.00 47.82  ? 17  VAL H CA   1 
ATOM   11392 C  C    . VAL H 2 17  ? 2.425   -31.552 47.127  1.00 59.27  ? 17  VAL H C    1 
ATOM   11393 O  O    . VAL H 2 17  ? 1.845   -32.223 47.983  1.00 57.23  ? 17  VAL H O    1 
ATOM   11394 C  CB   . VAL H 2 17  ? 4.329   -32.028 45.518  1.00 55.39  ? 17  VAL H CB   1 
ATOM   11395 C  CG1  . VAL H 2 17  ? 5.832   -32.057 45.377  1.00 52.67  ? 17  VAL H CG1  1 
ATOM   11396 C  CG2  . VAL H 2 17  ? 3.764   -33.408 45.200  1.00 52.34  ? 17  VAL H CG2  1 
ATOM   11397 N  N    . GLU H 2 18  ? 1.800   -30.686 46.338  1.00 59.11  ? 18  GLU H N    1 
ATOM   11398 C  CA   . GLU H 2 18  ? 0.324   -30.572 46.362  1.00 59.08  ? 18  GLU H CA   1 
ATOM   11399 C  C    . GLU H 2 18  ? -0.160  -30.700 44.918  1.00 57.91  ? 18  GLU H C    1 
ATOM   11400 O  O    . GLU H 2 18  ? 0.591   -30.349 44.011  1.00 61.46  ? 18  GLU H O    1 
ATOM   11401 C  CB   . GLU H 2 18  ? -0.106  -29.254 47.008  1.00 57.62  ? 18  GLU H CB   1 
ATOM   11402 C  CG   . GLU H 2 18  ? -0.342  -29.361 48.500  1.00 60.04  ? 18  GLU H CG   1 
ATOM   11403 C  CD   . GLU H 2 18  ? -1.487  -30.275 48.896  1.00 70.50  ? 18  GLU H CD   1 
ATOM   11404 O  OE1  . GLU H 2 18  ? -2.649  -29.875 48.706  1.00 77.06  ? 18  GLU H OE1  1 
ATOM   11405 O  OE2  . GLU H 2 18  ? -1.213  -31.384 49.395  1.00 69.79  ? 18  GLU H OE2  1 
ATOM   11406 N  N    . PRO H 2 19  ? -1.369  -31.225 44.667  1.00 59.43  ? 19  PRO H N    1 
ATOM   11407 C  CA   . PRO H 2 19  ? -1.887  -31.316 43.310  1.00 58.98  ? 19  PRO H CA   1 
ATOM   11408 C  C    . PRO H 2 19  ? -1.846  -29.977 42.566  1.00 57.74  ? 19  PRO H C    1 
ATOM   11409 O  O    . PRO H 2 19  ? -1.522  -29.981 41.406  1.00 59.12  ? 19  PRO H O    1 
ATOM   11410 C  CB   . PRO H 2 19  ? -3.335  -31.736 43.565  1.00 57.13  ? 19  PRO H CB   1 
ATOM   11411 C  CG   . PRO H 2 19  ? -3.290  -32.529 44.837  1.00 55.87  ? 19  PRO H CG   1 
ATOM   11412 C  CD   . PRO H 2 19  ? -2.267  -31.796 45.670  1.00 60.22  ? 19  PRO H CD   1 
ATOM   11413 N  N    . SER H 2 20  ? -2.151  -28.881 43.256  1.00 60.32  ? 20  SER H N    1 
ATOM   11414 C  CA   . SER H 2 20  ? -2.192  -27.530 42.640  1.00 63.43  ? 20  SER H CA   1 
ATOM   11415 C  C    . SER H 2 20  ? -0.791  -26.992 42.364  1.00 63.51  ? 20  SER H C    1 
ATOM   11416 O  O    . SER H 2 20  ? -0.695  -25.978 41.672  1.00 68.23  ? 20  SER H O    1 
ATOM   11417 C  CB   . SER H 2 20  ? -2.929  -26.582 43.533  1.00 56.02  ? 20  SER H CB   1 
ATOM   11418 O  OG   . SER H 2 20  ? -2.307  -26.497 44.805  1.00 58.23  ? 20  SER H OG   1 
ATOM   11419 N  N    . ASP H 2 21  ? 0.237   -27.620 42.922  1.00 59.56  ? 21  ASP H N    1 
ATOM   11420 C  CA   . ASP H 2 21  ? 1.606   -27.075 42.767  1.00 60.65  ? 21  ASP H CA   1 
ATOM   11421 C  C    . ASP H 2 21  ? 1.995   -27.111 41.294  1.00 63.69  ? 21  ASP H C    1 
ATOM   11422 O  O    . ASP H 2 21  ? 1.790   -28.151 40.663  1.00 62.80  ? 21  ASP H O    1 
ATOM   11423 C  CB   . ASP H 2 21  ? 2.612   -27.822 43.642  1.00 60.19  ? 21  ASP H CB   1 
ATOM   11424 C  CG   . ASP H 2 21  ? 2.603   -27.407 45.098  1.00 64.93  ? 21  ASP H CG   1 
ATOM   11425 O  OD1  . ASP H 2 21  ? 2.180   -26.274 45.388  1.00 71.07  ? 21  ASP H OD1  1 
ATOM   11426 O  OD2  . ASP H 2 21  ? 3.025   -28.221 45.923  1.00 62.43  ? 21  ASP H OD2  1 
ATOM   11427 N  N    . THR H 2 22  ? 2.561   -26.017 40.789  1.00 60.34  ? 22  THR H N    1 
ATOM   11428 C  CA   . THR H 2 22  ? 3.030   -26.000 39.415  1.00 60.80  ? 22  THR H CA   1 
ATOM   11429 C  C    . THR H 2 22  ? 4.348   -26.767 39.303  1.00 59.38  ? 22  THR H C    1 
ATOM   11430 O  O    . THR H 2 22  ? 4.972   -27.135 40.307  1.00 53.75  ? 22  THR H O    1 
ATOM   11431 C  CB   . THR H 2 22  ? 3.236   -24.568 38.928  1.00 64.09  ? 22  THR H CB   1 
ATOM   11432 O  OG1  . THR H 2 22  ? 4.330   -23.981 39.660  1.00 60.66  ? 22  THR H OG1  1 
ATOM   11433 C  CG2  . THR H 2 22  ? 1.958   -23.755 39.111  1.00 59.77  ? 22  THR H CG2  1 
ATOM   11434 N  N    . ILE H 2 23  ? 4.790   -26.972 38.054  1.00 57.98  ? 23  ILE H N    1 
ATOM   11435 C  CA   . ILE H 2 23  ? 6.028   -27.717 37.825  1.00 59.27  ? 23  ILE H CA   1 
ATOM   11436 C  C    . ILE H 2 23  ? 7.221   -26.962 38.398  1.00 55.81  ? 23  ILE H C    1 
ATOM   11437 O  O    . ILE H 2 23  ? 8.110   -27.558 39.018  1.00 55.56  ? 23  ILE H O    1 
ATOM   11438 C  CB   . ILE H 2 23  ? 6.213   -28.021 36.329  1.00 56.11  ? 23  ILE H CB   1 
ATOM   11439 C  CG1  . ILE H 2 23  ? 5.079   -28.915 35.809  1.00 56.61  ? 23  ILE H CG1  1 
ATOM   11440 C  CG2  . ILE H 2 23  ? 7.546   -28.679 36.106  1.00 56.28  ? 23  ILE H CG2  1 
ATOM   11441 C  CD1  . ILE H 2 23  ? 4.764   -30.106 36.720  1.00 57.88  ? 23  ILE H CD1  1 
ATOM   11442 N  N    . GLU H 2 24  ? 7.254   -25.639 38.220  1.00 61.64  ? 24  GLU H N    1 
ATOM   11443 C  CA   . GLU H 2 24  ? 8.321   -24.841 38.820  1.00 55.07  ? 24  GLU H CA   1 
ATOM   11444 C  C    . GLU H 2 24  ? 8.324   -24.979 40.333  1.00 52.71  ? 24  GLU H C    1 
ATOM   11445 O  O    . GLU H 2 24  ? 9.394   -24.987 40.945  1.00 54.65  ? 24  GLU H O    1 
ATOM   11446 C  CB   . GLU H 2 24  ? 8.191   -23.371 38.417  1.00 56.46  ? 24  GLU H CB   1 
ATOM   11447 C  CG   . GLU H 2 24  ? 7.989   -23.129 36.930  1.00 56.97  ? 24  GLU H CG   1 
ATOM   11448 C  CD   . GLU H 2 24  ? 6.506   -22.976 36.582  1.00 71.04  ? 24  GLU H CD   1 
ATOM   11449 O  OE1  . GLU H 2 24  ? 5.680   -23.740 37.130  1.00 68.52  ? 24  GLU H OE1  1 
ATOM   11450 O  OE2  . GLU H 2 24  ? 6.154   -22.099 35.763  1.00 73.35  ? 24  GLU H OE2  1 
ATOM   11451 N  N    . ASN H 2 25  ? 7.147   -25.137 40.927  1.00 51.49  ? 25  ASN H N    1 
ATOM   11452 C  CA   . ASN H 2 25  ? 7.092   -25.368 42.390  1.00 52.79  ? 25  ASN H CA   1 
ATOM   11453 C  C    . ASN H 2 25  ? 7.754   -26.711 42.710  1.00 56.59  ? 25  ASN H C    1 
ATOM   11454 O  O    . ASN H 2 25  ? 8.518   -26.760 43.679  1.00 56.87  ? 25  ASN H O    1 
ATOM   11455 C  CB   . ASN H 2 25  ? 5.667   -25.282 42.938  1.00 55.92  ? 25  ASN H CB   1 
ATOM   11456 C  CG   . ASN H 2 25  ? 5.057   -23.902 42.848  1.00 67.97  ? 25  ASN H CG   1 
ATOM   11457 O  OD1  . ASN H 2 25  ? 5.767   -22.907 42.732  1.00 67.88  ? 25  ASN H OD1  1 
ATOM   11458 N  ND2  . ASN H 2 25  ? 3.738   -23.832 42.904  1.00 66.15  ? 25  ASN H ND2  1 
ATOM   11459 N  N    . VAL H 2 26  ? 7.466   -27.754 41.930  1.00 51.24  ? 26  VAL H N    1 
ATOM   11460 C  CA   . VAL H 2 26  ? 8.093   -29.052 42.143  1.00 53.16  ? 26  VAL H CA   1 
ATOM   11461 C  C    . VAL H 2 26  ? 9.588   -28.930 41.967  1.00 49.96  ? 26  VAL H C    1 
ATOM   11462 O  O    . VAL H 2 26  ? 10.363  -29.443 42.786  1.00 51.12  ? 26  VAL H O    1 
ATOM   11463 C  CB   . VAL H 2 26  ? 7.501   -30.114 41.195  1.00 54.43  ? 26  VAL H CB   1 
ATOM   11464 C  CG1  . VAL H 2 26  ? 8.208   -31.444 41.383  1.00 43.33  ? 26  VAL H CG1  1 
ATOM   11465 C  CG2  . VAL H 2 26  ? 6.033   -30.263 41.439  1.00 46.11  ? 26  VAL H CG2  1 
ATOM   11466 N  N    . LYS H 2 27  ? 10.022  -28.231 40.908  1.00 48.24  ? 27  LYS H N    1 
ATOM   11467 C  CA   . LYS H 2 27  ? 11.456  -28.067 40.685  1.00 50.94  ? 27  LYS H CA   1 
ATOM   11468 C  C    . LYS H 2 27  ? 12.096  -27.322 41.846  1.00 54.32  ? 27  LYS H C    1 
ATOM   11469 O  O    . LYS H 2 27  ? 13.166  -27.716 42.335  1.00 55.92  ? 27  LYS H O    1 
ATOM   11470 C  CB   . LYS H 2 27  ? 11.728  -27.347 39.363  1.00 54.36  ? 27  LYS H CB   1 
ATOM   11471 C  CG   . LYS H 2 27  ? 11.428  -28.175 38.110  1.00 52.15  ? 27  LYS H CG   1 
ATOM   11472 C  CD   . LYS H 2 27  ? 11.496  -27.314 36.860  1.00 50.33  ? 27  LYS H CD   1 
ATOM   11473 C  CE   . LYS H 2 27  ? 11.208  -28.125 35.613  1.00 48.15  ? 27  LYS H CE   1 
ATOM   11474 N  NZ   . LYS H 2 27  ? 10.964  -27.283 34.397  1.00 52.91  ? 27  LYS H NZ   1 
ATOM   11475 N  N    . ALA H 2 28  ? 11.442  -26.262 42.324  1.00 49.22  ? 28  ALA H N    1 
ATOM   11476 C  CA   . ALA H 2 28  ? 11.945  -25.582 43.511  1.00 52.53  ? 28  ALA H CA   1 
ATOM   11477 C  C    . ALA H 2 28  ? 12.091  -26.572 44.661  1.00 55.27  ? 28  ALA H C    1 
ATOM   11478 O  O    . ALA H 2 28  ? 13.115  -26.589 45.363  1.00 51.62  ? 28  ALA H O    1 
ATOM   11479 C  CB   . ALA H 2 28  ? 11.023  -24.412 43.898  1.00 38.60  ? 28  ALA H CB   1 
ATOM   11480 N  N    . LYS H 2 29  ? 11.090  -27.436 44.843  1.00 55.91  ? 29  LYS H N    1 
ATOM   11481 C  CA   . LYS H 2 29  ? 11.168  -28.395 45.937  1.00 54.32  ? 29  LYS H CA   1 
ATOM   11482 C  C    . LYS H 2 29  ? 12.320  -29.368 45.729  1.00 48.92  ? 29  LYS H C    1 
ATOM   11483 O  O    . LYS H 2 29  ? 13.023  -29.721 46.681  1.00 51.39  ? 29  LYS H O    1 
ATOM   11484 C  CB   . LYS H 2 29  ? 9.836   -29.122 46.079  1.00 58.25  ? 29  LYS H CB   1 
ATOM   11485 C  CG   . LYS H 2 29  ? 8.859   -28.355 46.923  1.00 55.38  ? 29  LYS H CG   1 
ATOM   11486 C  CD   . LYS H 2 29  ? 7.436   -28.884 46.808  1.00 58.91  ? 29  LYS H CD   1 
ATOM   11487 C  CE   . LYS H 2 29  ? 6.597   -28.286 47.923  1.00 60.31  ? 29  LYS H CE   1 
ATOM   11488 N  NZ   . LYS H 2 29  ? 5.278   -27.865 47.417  1.00 63.25  ? 29  LYS H NZ   1 
ATOM   11489 N  N    . ILE H 2 30  ? 12.557  -29.780 44.484  1.00 50.15  ? 30  ILE H N    1 
ATOM   11490 C  CA   . ILE H 2 30  ? 13.703  -30.646 44.203  1.00 50.81  ? 30  ILE H CA   1 
ATOM   11491 C  C    . ILE H 2 30  ? 15.007  -29.905 44.488  1.00 54.30  ? 30  ILE H C    1 
ATOM   11492 O  O    . ILE H 2 30  ? 15.982  -30.484 44.993  1.00 48.43  ? 30  ILE H O    1 
ATOM   11493 C  CB   . ILE H 2 30  ? 13.644  -31.151 42.752  1.00 45.92  ? 30  ILE H CB   1 
ATOM   11494 C  CG1  . ILE H 2 30  ? 12.466  -32.123 42.575  1.00 47.78  ? 30  ILE H CG1  1 
ATOM   11495 C  CG2  . ILE H 2 30  ? 14.967  -31.772 42.350  1.00 45.49  ? 30  ILE H CG2  1 
ATOM   11496 C  CD1  . ILE H 2 30  ? 12.136  -32.410 41.149  1.00 44.11  ? 30  ILE H CD1  1 
ATOM   11497 N  N    . GLN H 2 31  ? 15.041  -28.603 44.195  1.00 50.74  ? 31  GLN H N    1 
ATOM   11498 C  CA   . GLN H 2 31  ? 16.228  -27.838 44.557  1.00 56.01  ? 31  GLN H CA   1 
ATOM   11499 C  C    . GLN H 2 31  ? 16.429  -27.821 46.071  1.00 52.42  ? 31  GLN H C    1 
ATOM   11500 O  O    . GLN H 2 31  ? 17.553  -28.010 46.545  1.00 51.16  ? 31  GLN H O    1 
ATOM   11501 C  CB   . GLN H 2 31  ? 16.151  -26.421 43.990  1.00 53.51  ? 31  GLN H CB   1 
ATOM   11502 C  CG   . GLN H 2 31  ? 17.378  -25.591 44.319  1.00 57.44  ? 31  GLN H CG   1 
ATOM   11503 C  CD   . GLN H 2 31  ? 17.329  -24.203 43.704  1.00 57.66  ? 31  GLN H CD   1 
ATOM   11504 O  OE1  . GLN H 2 31  ? 16.289  -23.542 43.695  1.00 61.71  ? 31  GLN H OE1  1 
ATOM   11505 N  NE2  . GLN H 2 31  ? 18.459  -23.756 43.187  1.00 59.66  ? 31  GLN H NE2  1 
ATOM   11506 N  N    . ASP H 2 32  ? 15.346  -27.644 46.849  1.00 52.12  ? 32  ASP H N    1 
ATOM   11507 C  CA   . ASP H 2 32  ? 15.480  -27.641 48.309  1.00 43.77  ? 32  ASP H CA   1 
ATOM   11508 C  C    . ASP H 2 32  ? 16.055  -28.954 48.815  1.00 52.15  ? 32  ASP H C    1 
ATOM   11509 O  O    . ASP H 2 32  ? 16.816  -28.968 49.789  1.00 47.26  ? 32  ASP H O    1 
ATOM   11510 C  CB   . ASP H 2 32  ? 14.132  -27.369 48.992  1.00 46.40  ? 32  ASP H CB   1 
ATOM   11511 C  CG   . ASP H 2 32  ? 14.180  -27.554 50.555  1.00 61.56  ? 32  ASP H CG   1 
ATOM   11512 O  OD1  . ASP H 2 32  ? 14.605  -26.621 51.306  1.00 56.62  ? 32  ASP H OD1  1 
ATOM   11513 O  OD2  . ASP H 2 32  ? 13.778  -28.645 51.040  1.00 59.91  ? 32  ASP H OD2  1 
ATOM   11514 N  N    . LYS H 2 33  ? 15.683  -30.074 48.193  1.00 52.68  ? 33  LYS H N    1 
ATOM   11515 C  CA   . LYS H 2 33  ? 16.087  -31.364 48.725  1.00 48.78  ? 33  LYS H CA   1 
ATOM   11516 C  C    . LYS H 2 33  ? 17.320  -31.930 48.045  1.00 50.54  ? 33  LYS H C    1 
ATOM   11517 O  O    . LYS H 2 33  ? 18.148  -32.540 48.721  1.00 52.90  ? 33  LYS H O    1 
ATOM   11518 C  CB   . LYS H 2 33  ? 14.940  -32.370 48.622  1.00 53.42  ? 33  LYS H CB   1 
ATOM   11519 C  CG   . LYS H 2 33  ? 15.120  -33.624 49.508  1.00 51.49  ? 33  LYS H CG   1 
ATOM   11520 C  CD   . LYS H 2 33  ? 13.784  -34.407 49.615  1.00 59.06  ? 33  LYS H CD   1 
ATOM   11521 C  CE   . LYS H 2 33  ? 13.733  -35.330 50.847  1.00 56.96  ? 33  LYS H CE   1 
ATOM   11522 N  NZ   . LYS H 2 33  ? 12.514  -36.203 50.885  1.00 54.80  ? 33  LYS H NZ   1 
ATOM   11523 N  N    . GLU H 2 34  ? 17.458  -31.745 46.730  1.00 51.94  ? 34  GLU H N    1 
ATOM   11524 C  CA   . GLU H 2 34  ? 18.539  -32.326 45.944  1.00 54.57  ? 34  GLU H CA   1 
ATOM   11525 C  C    . GLU H 2 34  ? 19.560  -31.312 45.439  1.00 55.51  ? 34  GLU H C    1 
ATOM   11526 O  O    . GLU H 2 34  ? 20.586  -31.725 44.887  1.00 54.20  ? 34  GLU H O    1 
ATOM   11527 C  CB   . GLU H 2 34  ? 17.974  -33.076 44.723  1.00 52.20  ? 34  GLU H CB   1 
ATOM   11528 C  CG   . GLU H 2 34  ? 17.598  -34.503 45.000  1.00 61.99  ? 34  GLU H CG   1 
ATOM   11529 C  CD   . GLU H 2 34  ? 18.801  -35.415 45.117  1.00 63.61  ? 34  GLU H CD   1 
ATOM   11530 O  OE1  . GLU H 2 34  ? 19.536  -35.585 44.113  1.00 60.46  ? 34  GLU H OE1  1 
ATOM   11531 O  OE2  . GLU H 2 34  ? 19.009  -35.954 46.226  1.00 63.30  ? 34  GLU H OE2  1 
ATOM   11532 N  N    . GLY H 2 35  ? 19.294  -30.007 45.559  1.00 54.04  ? 35  GLY H N    1 
ATOM   11533 C  CA   . GLY H 2 35  ? 20.257  -28.996 45.167  1.00 49.77  ? 35  GLY H CA   1 
ATOM   11534 C  C    . GLY H 2 35  ? 20.362  -28.729 43.677  1.00 55.94  ? 35  GLY H C    1 
ATOM   11535 O  O    . GLY H 2 35  ? 21.021  -27.758 43.289  1.00 63.63  ? 35  GLY H O    1 
ATOM   11536 N  N    . ILE H 2 36  ? 19.732  -29.541 42.833  1.00 54.50  ? 36  ILE H N    1 
ATOM   11537 C  CA   . ILE H 2 36  ? 19.721  -29.319 41.391  1.00 58.35  ? 36  ILE H CA   1 
ATOM   11538 C  C    . ILE H 2 36  ? 18.982  -28.014 41.118  1.00 58.28  ? 36  ILE H C    1 
ATOM   11539 O  O    . ILE H 2 36  ? 17.804  -27.892 41.480  1.00 56.77  ? 36  ILE H O    1 
ATOM   11540 C  CB   . ILE H 2 36  ? 19.057  -30.487 40.639  1.00 55.71  ? 36  ILE H CB   1 
ATOM   11541 C  CG1  . ILE H 2 36  ? 19.423  -31.836 41.261  1.00 57.09  ? 36  ILE H CG1  1 
ATOM   11542 C  CG2  . ILE H 2 36  ? 19.430  -30.463 39.169  1.00 55.47  ? 36  ILE H CG2  1 
ATOM   11543 C  CD1  . ILE H 2 36  ? 20.902  -32.156 41.169  1.00 64.60  ? 36  ILE H CD1  1 
ATOM   11544 N  N    . PRO H 2 37  ? 19.616  -27.026 40.492  1.00 59.71  ? 37  PRO H N    1 
ATOM   11545 C  CA   . PRO H 2 37  ? 18.903  -25.804 40.120  1.00 57.67  ? 37  PRO H CA   1 
ATOM   11546 C  C    . PRO H 2 37  ? 17.758  -26.134 39.183  1.00 59.48  ? 37  PRO H C    1 
ATOM   11547 O  O    . PRO H 2 37  ? 17.885  -27.042 38.349  1.00 59.16  ? 37  PRO H O    1 
ATOM   11548 C  CB   . PRO H 2 37  ? 19.977  -24.963 39.403  1.00 57.01  ? 37  PRO H CB   1 
ATOM   11549 C  CG   . PRO H 2 37  ? 21.279  -25.614 39.693  1.00 59.93  ? 37  PRO H CG   1 
ATOM   11550 C  CD   . PRO H 2 37  ? 20.978  -27.062 39.932  1.00 66.68  ? 37  PRO H CD   1 
ATOM   11551 N  N    . PRO H 2 38  ? 16.629  -25.426 39.294  1.00 52.77  ? 38  PRO H N    1 
ATOM   11552 C  CA   . PRO H 2 38  ? 15.484  -25.716 38.411  1.00 56.78  ? 38  PRO H CA   1 
ATOM   11553 C  C    . PRO H 2 38  ? 15.776  -25.545 36.932  1.00 60.57  ? 38  PRO H C    1 
ATOM   11554 O  O    . PRO H 2 38  ? 15.043  -26.111 36.107  1.00 59.06  ? 38  PRO H O    1 
ATOM   11555 C  CB   . PRO H 2 38  ? 14.412  -24.719 38.881  1.00 51.98  ? 38  PRO H CB   1 
ATOM   11556 C  CG   . PRO H 2 38  ? 14.753  -24.472 40.327  1.00 54.14  ? 38  PRO H CG   1 
ATOM   11557 C  CD   . PRO H 2 38  ? 16.270  -24.534 40.406  1.00 54.57  ? 38  PRO H CD   1 
ATOM   11558 N  N    . ASP H 2 39  ? 16.809  -24.778 36.571  1.00 62.20  ? 39  ASP H N    1 
ATOM   11559 C  CA   . ASP H 2 39  ? 17.125  -24.548 35.163  1.00 62.46  ? 39  ASP H CA   1 
ATOM   11560 C  C    . ASP H 2 39  ? 17.681  -25.797 34.497  1.00 63.01  ? 39  ASP H C    1 
ATOM   11561 O  O    . ASP H 2 39  ? 17.544  -25.953 33.279  1.00 59.97  ? 39  ASP H O    1 
ATOM   11562 C  CB   . ASP H 2 39  ? 18.137  -23.402 35.016  1.00 63.78  ? 39  ASP H CB   1 
ATOM   11563 C  CG   . ASP H 2 39  ? 17.471  -22.016 34.993  1.00 77.38  ? 39  ASP H CG   1 
ATOM   11564 O  OD1  . ASP H 2 39  ? 16.283  -21.919 34.575  1.00 72.49  ? 39  ASP H OD1  1 
ATOM   11565 O  OD2  . ASP H 2 39  ? 18.140  -21.027 35.402  1.00 72.17  ? 39  ASP H OD2  1 
ATOM   11566 N  N    . GLN H 2 40  ? 18.345  -26.672 35.261  1.00 60.96  ? 40  GLN H N    1 
ATOM   11567 C  CA   . GLN H 2 40  ? 18.920  -27.897 34.713  1.00 60.58  ? 40  GLN H CA   1 
ATOM   11568 C  C    . GLN H 2 40  ? 17.969  -29.087 34.794  1.00 58.18  ? 40  GLN H C    1 
ATOM   11569 O  O    . GLN H 2 40  ? 18.243  -30.121 34.177  1.00 58.37  ? 40  GLN H O    1 
ATOM   11570 N  N    . GLN H 2 41  ? 16.864  -28.951 35.526  1.00 58.00  ? 41  GLN H N    1 
ATOM   11571 C  CA   . GLN H 2 41  ? 15.943  -30.044 35.803  1.00 57.40  ? 41  GLN H CA   1 
ATOM   11572 C  C    . GLN H 2 41  ? 14.989  -30.295 34.641  1.00 52.62  ? 41  GLN H C    1 
ATOM   11573 O  O    . GLN H 2 41  ? 14.318  -29.374 34.171  1.00 54.02  ? 41  GLN H O    1 
ATOM   11574 C  CB   . GLN H 2 41  ? 15.111  -29.720 37.040  1.00 52.20  ? 41  GLN H CB   1 
ATOM   11575 C  CG   . GLN H 2 41  ? 15.829  -29.743 38.354  1.00 52.83  ? 41  GLN H CG   1 
ATOM   11576 C  CD   . GLN H 2 41  ? 14.860  -29.464 39.483  1.00 53.52  ? 41  GLN H CD   1 
ATOM   11577 O  OE1  . GLN H 2 41  ? 13.687  -29.827 39.397  1.00 48.50  ? 41  GLN H OE1  1 
ATOM   11578 N  NE2  . GLN H 2 41  ? 15.326  -28.769 40.520  1.00 53.69  ? 41  GLN H NE2  1 
ATOM   11579 N  N    . ARG H 2 42  ? 14.895  -31.552 34.215  1.00 51.11  ? 42  ARG H N    1 
ATOM   11580 C  CA   . ARG H 2 42  ? 13.810  -32.040 33.369  1.00 48.33  ? 42  ARG H CA   1 
ATOM   11581 C  C    . ARG H 2 42  ? 13.153  -33.213 34.081  1.00 47.25  ? 42  ARG H C    1 
ATOM   11582 O  O    . ARG H 2 42  ? 13.836  -33.993 34.759  1.00 52.76  ? 42  ARG H O    1 
ATOM   11583 C  CB   . ARG H 2 42  ? 14.305  -32.470 31.984  1.00 44.25  ? 42  ARG H CB   1 
ATOM   11584 C  CG   . ARG H 2 42  ? 15.009  -31.375 31.194  1.00 53.47  ? 42  ARG H CG   1 
ATOM   11585 C  CD   . ARG H 2 42  ? 15.821  -31.930 30.020  1.00 52.46  ? 42  ARG H CD   1 
ATOM   11586 N  NE   . ARG H 2 42  ? 15.030  -32.899 29.294  1.00 61.66  ? 42  ARG H NE   1 
ATOM   11587 C  CZ   . ARG H 2 42  ? 15.495  -34.032 28.785  1.00 60.95  ? 42  ARG H CZ   1 
ATOM   11588 N  NH1  . ARG H 2 42  ? 16.777  -34.346 28.887  1.00 57.91  ? 42  ARG H NH1  1 
ATOM   11589 N  NH2  . ARG H 2 42  ? 14.660  -34.848 28.165  1.00 63.49  ? 42  ARG H NH2  1 
ATOM   11590 N  N    . LEU H 2 43  ? 11.837  -33.351 33.920  1.00 45.76  ? 43  LEU H N    1 
ATOM   11591 C  CA   . LEU H 2 43  ? 11.029  -34.242 34.752  1.00 46.76  ? 43  LEU H CA   1 
ATOM   11592 C  C    . LEU H 2 43  ? 10.158  -35.109 33.854  1.00 51.63  ? 43  LEU H C    1 
ATOM   11593 O  O    . LEU H 2 43  ? 9.175   -34.627 33.282  1.00 45.58  ? 43  LEU H O    1 
ATOM   11594 C  CB   . LEU H 2 43  ? 10.169  -33.433 35.726  1.00 52.01  ? 43  LEU H CB   1 
ATOM   11595 C  CG   . LEU H 2 43  ? 10.911  -32.750 36.889  1.00 52.68  ? 43  LEU H CG   1 
ATOM   11596 C  CD1  . LEU H 2 43  ? 10.008  -31.770 37.674  1.00 44.71  ? 43  LEU H CD1  1 
ATOM   11597 C  CD2  . LEU H 2 43  ? 11.520  -33.814 37.812  1.00 51.04  ? 43  LEU H CD2  1 
ATOM   11598 N  N    . ILE H 2 44  ? 10.511  -36.387 33.724  1.00 53.27  ? 44  ILE H N    1 
ATOM   11599 C  CA   . ILE H 2 44  ? 9.797   -37.292 32.832  1.00 49.94  ? 44  ILE H CA   1 
ATOM   11600 C  C    . ILE H 2 44  ? 8.772   -38.069 33.642  1.00 55.81  ? 44  ILE H C    1 
ATOM   11601 O  O    . ILE H 2 44  ? 9.126   -38.773 34.603  1.00 53.63  ? 44  ILE H O    1 
ATOM   11602 C  CB   . ILE H 2 44  ? 10.752  -38.244 32.102  1.00 50.08  ? 44  ILE H CB   1 
ATOM   11603 C  CG1  . ILE H 2 44  ? 11.872  -37.441 31.468  1.00 50.68  ? 44  ILE H CG1  1 
ATOM   11604 C  CG2  . ILE H 2 44  ? 9.988   -39.025 31.013  1.00 45.85  ? 44  ILE H CG2  1 
ATOM   11605 C  CD1  . ILE H 2 44  ? 11.384  -36.511 30.417  1.00 49.06  ? 44  ILE H CD1  1 
ATOM   11606 N  N    . PHE H 2 45  ? 7.501   -37.968 33.236  1.00 48.95  ? 45  PHE H N    1 
ATOM   11607 C  CA   . PHE H 2 45  ? 6.422   -38.783 33.849  1.00 53.11  ? 45  PHE H CA   1 
ATOM   11608 C  C    . PHE H 2 45  ? 5.553   -39.363 32.734  1.00 51.84  ? 45  PHE H C    1 
ATOM   11609 O  O    . PHE H 2 45  ? 5.079   -38.576 31.907  1.00 51.83  ? 45  PHE H O    1 
ATOM   11610 C  CB   . PHE H 2 45  ? 5.534   -37.979 34.798  1.00 49.63  ? 45  PHE H CB   1 
ATOM   11611 C  CG   . PHE H 2 45  ? 4.346   -38.738 35.330  1.00 50.59  ? 45  PHE H CG   1 
ATOM   11612 C  CD1  . PHE H 2 45  ? 4.510   -39.721 36.290  1.00 48.03  ? 45  PHE H CD1  1 
ATOM   11613 C  CD2  . PHE H 2 45  ? 3.067   -38.481 34.862  1.00 51.04  ? 45  PHE H CD2  1 
ATOM   11614 C  CE1  . PHE H 2 45  ? 3.421   -40.425 36.777  1.00 52.18  ? 45  PHE H CE1  1 
ATOM   11615 C  CE2  . PHE H 2 45  ? 1.980   -39.188 35.348  1.00 47.98  ? 45  PHE H CE2  1 
ATOM   11616 C  CZ   . PHE H 2 45  ? 2.159   -40.156 36.306  1.00 48.17  ? 45  PHE H CZ   1 
ATOM   11617 N  N    . ALA H 2 46  ? 5.351   -40.683 32.722  1.00 53.50  ? 46  ALA H N    1 
ATOM   11618 C  CA   . ALA H 2 46  ? 4.479   -41.360 31.729  1.00 54.16  ? 46  ALA H CA   1 
ATOM   11619 C  C    . ALA H 2 46  ? 4.809   -40.951 30.290  1.00 50.06  ? 46  ALA H C    1 
ATOM   11620 O  O    . ALA H 2 46  ? 3.867   -40.701 29.525  1.00 56.04  ? 46  ALA H O    1 
ATOM   11621 C  CB   . ALA H 2 46  ? 3.036   -41.106 32.072  1.00 46.01  ? 46  ALA H CB   1 
ATOM   11622 N  N    . GLY H 2 47  ? 6.093   -40.881 29.944  1.00 48.87  ? 47  GLY H N    1 
ATOM   11623 C  CA   . GLY H 2 47  ? 6.529   -40.523 28.581  1.00 52.56  ? 47  GLY H CA   1 
ATOM   11624 C  C    . GLY H 2 47  ? 6.405   -39.046 28.259  1.00 59.88  ? 47  GLY H C    1 
ATOM   11625 O  O    . GLY H 2 47  ? 6.653   -38.681 27.103  1.00 58.15  ? 47  GLY H O    1 
ATOM   11626 N  N    . LYS H 2 48  ? 6.025   -38.224 29.231  1.00 57.14  ? 48  LYS H N    1 
ATOM   11627 C  CA   . LYS H 2 48  ? 5.802   -36.787 28.955  1.00 57.56  ? 48  LYS H CA   1 
ATOM   11628 C  C    . LYS H 2 48  ? 6.781   -35.942 29.761  1.00 53.93  ? 48  LYS H C    1 
ATOM   11629 O  O    . LYS H 2 48  ? 7.014   -36.264 30.927  1.00 55.29  ? 48  LYS H O    1 
ATOM   11630 C  CB   . LYS H 2 48  ? 4.363   -36.397 29.297  1.00 56.93  ? 48  LYS H CB   1 
ATOM   11631 C  CG   . LYS H 2 48  ? 3.299   -36.901 28.334  1.00 57.23  ? 48  LYS H CG   1 
ATOM   11632 N  N    . GLN H 2 49  ? 7.357   -34.922 29.134  1.00 53.46  ? 49  GLN H N    1 
ATOM   11633 C  CA   . GLN H 2 49  ? 8.197   -33.978 29.905  1.00 55.19  ? 49  GLN H CA   1 
ATOM   11634 C  C    . GLN H 2 49  ? 7.249   -32.961 30.522  1.00 49.12  ? 49  GLN H C    1 
ATOM   11635 O  O    . GLN H 2 49  ? 6.496   -32.328 29.774  1.00 55.63  ? 49  GLN H O    1 
ATOM   11636 C  CB   . GLN H 2 49  ? 9.255   -33.276 29.059  1.00 52.96  ? 49  GLN H CB   1 
ATOM   11637 C  CG   . GLN H 2 49  ? 10.244  -32.479 29.894  1.00 49.06  ? 49  GLN H CG   1 
ATOM   11638 C  CD   . GLN H 2 49  ? 11.532  -32.223 29.156  1.00 59.53  ? 49  GLN H CD   1 
ATOM   11639 O  OE1  . GLN H 2 49  ? 12.200  -33.143 28.699  1.00 61.71  ? 49  GLN H OE1  1 
ATOM   11640 N  NE2  . GLN H 2 49  ? 11.888  -30.957 29.038  1.00 58.27  ? 49  GLN H NE2  1 
ATOM   11641 N  N    . LEU H 2 50  ? 7.284   -32.846 31.841  1.00 47.28  ? 50  LEU H N    1 
ATOM   11642 C  CA   . LEU H 2 50  ? 6.381   -31.917 32.552  1.00 52.24  ? 50  LEU H CA   1 
ATOM   11643 C  C    . LEU H 2 50  ? 6.774   -30.488 32.179  1.00 57.06  ? 50  LEU H C    1 
ATOM   11644 O  O    . LEU H 2 50  ? 7.976   -30.226 32.005  1.00 53.17  ? 50  LEU H O    1 
ATOM   11645 C  CB   . LEU H 2 50  ? 6.475   -32.203 34.050  1.00 51.66  ? 50  LEU H CB   1 
ATOM   11646 C  CG   . LEU H 2 50  ? 6.269   -33.655 34.474  1.00 48.79  ? 50  LEU H CG   1 
ATOM   11647 C  CD1  . LEU H 2 50  ? 6.206   -33.765 35.985  1.00 41.39  ? 50  LEU H CD1  1 
ATOM   11648 C  CD2  . LEU H 2 50  ? 5.024   -34.252 33.845  1.00 51.41  ? 50  LEU H CD2  1 
ATOM   11649 N  N    . GLU H 2 51  ? 5.795   -29.597 32.066  1.00 55.65  ? 51  GLU H N    1 
ATOM   11650 C  CA   . GLU H 2 51  ? 6.088   -28.242 31.546  1.00 63.83  ? 51  GLU H CA   1 
ATOM   11651 C  C    . GLU H 2 51  ? 5.782   -27.126 32.537  1.00 65.67  ? 51  GLU H C    1 
ATOM   11652 O  O    . GLU H 2 51  ? 4.679   -27.124 33.099  1.00 62.03  ? 51  GLU H O    1 
ATOM   11653 C  CB   . GLU H 2 51  ? 5.230   -27.983 30.311  1.00 63.69  ? 51  GLU H CB   1 
ATOM   11654 C  CG   . GLU H 2 51  ? 5.779   -28.592 29.040  1.00 65.19  ? 51  GLU H CG   1 
ATOM   11655 C  CD   . GLU H 2 51  ? 4.867   -28.393 27.845  1.00 73.07  ? 51  GLU H CD   1 
ATOM   11656 O  OE1  . GLU H 2 51  ? 3.641   -28.522 28.013  1.00 71.65  ? 51  GLU H OE1  1 
ATOM   11657 O  OE2  . GLU H 2 51  ? 5.385   -28.104 26.753  1.00 77.17  ? 51  GLU H OE2  1 
ATOM   11658 N  N    . ASP H 2 52  ? 6.722   -26.203 32.717  1.00 59.55  ? 52  ASP H N    1 
ATOM   11659 C  CA   . ASP H 2 52  ? 6.490   -25.012 33.518  1.00 62.50  ? 52  ASP H CA   1 
ATOM   11660 C  C    . ASP H 2 52  ? 5.173   -24.354 33.122  1.00 68.38  ? 52  ASP H C    1 
ATOM   11661 O  O    . ASP H 2 52  ? 4.902   -24.126 31.935  1.00 61.80  ? 52  ASP H O    1 
ATOM   11662 C  CB   . ASP H 2 52  ? 7.646   -24.036 33.338  1.00 62.78  ? 52  ASP H CB   1 
ATOM   11663 C  CG   . ASP H 2 52  ? 8.958   -24.601 33.823  1.00 61.48  ? 52  ASP H CG   1 
ATOM   11664 O  OD1  . ASP H 2 52  ? 8.938   -25.637 34.514  1.00 59.20  ? 52  ASP H OD1  1 
ATOM   11665 O  OD2  . ASP H 2 52  ? 10.009  -24.011 33.514  1.00 63.88  ? 52  ASP H OD2  1 
ATOM   11666 N  N    . GLY H 2 53  ? 4.341   -24.067 34.129  1.00 68.27  ? 53  GLY H N    1 
ATOM   11667 C  CA   . GLY H 2 53  ? 3.044   -23.454 33.940  1.00 55.75  ? 53  GLY H CA   1 
ATOM   11668 C  C    . GLY H 2 53  ? 1.883   -24.395 34.192  1.00 62.65  ? 53  GLY H C    1 
ATOM   11669 O  O    . GLY H 2 53  ? 0.816   -23.944 34.633  1.00 66.40  ? 53  GLY H O    1 
ATOM   11670 N  N    . ARG H 2 54  ? 2.053   -25.679 33.896  1.00 58.61  ? 54  ARG H N    1 
ATOM   11671 C  CA   . ARG H 2 54  ? 1.032   -26.648 34.231  1.00 58.68  ? 54  ARG H CA   1 
ATOM   11672 C  C    . ARG H 2 54  ? 1.213   -27.071 35.679  1.00 61.67  ? 54  ARG H C    1 
ATOM   11673 O  O    . ARG H 2 54  ? 2.203   -26.731 36.328  1.00 63.44  ? 54  ARG H O    1 
ATOM   11674 C  CB   . ARG H 2 54  ? 1.086   -27.842 33.277  1.00 61.03  ? 54  ARG H CB   1 
ATOM   11675 C  CG   . ARG H 2 54  ? 1.147   -27.437 31.793  1.00 67.90  ? 54  ARG H CG   1 
ATOM   11676 C  CD   . ARG H 2 54  ? 0.402   -28.407 30.840  1.00 76.24  ? 54  ARG H CD   1 
ATOM   11677 N  NE   . ARG H 2 54  ? -1.036  -28.488 31.116  1.00 83.55  ? 54  ARG H NE   1 
ATOM   11678 C  CZ   . ARG H 2 54  ? -1.965  -27.719 30.549  1.00 81.04  ? 54  ARG H CZ   1 
ATOM   11679 N  NH1  . ARG H 2 54  ? -1.622  -26.796 29.656  1.00 81.18  ? 54  ARG H NH1  1 
ATOM   11680 N  NH2  . ARG H 2 54  ? -3.243  -27.877 30.880  1.00 80.93  ? 54  ARG H NH2  1 
ATOM   11681 N  N    . THR H 2 55  ? 0.234   -27.782 36.211  1.00 59.58  ? 55  THR H N    1 
ATOM   11682 C  CA   . THR H 2 55  ? 0.372   -28.312 37.559  1.00 60.97  ? 55  THR H CA   1 
ATOM   11683 C  C    . THR H 2 55  ? 0.356   -29.839 37.537  1.00 64.91  ? 55  THR H C    1 
ATOM   11684 O  O    . THR H 2 55  ? 0.178   -30.482 36.496  1.00 63.62  ? 55  THR H O    1 
ATOM   11685 C  CB   . THR H 2 55  ? -0.732  -27.785 38.472  1.00 63.25  ? 55  THR H CB   1 
ATOM   11686 O  OG1  . THR H 2 55  ? -1.966  -28.365 38.056  1.00 67.90  ? 55  THR H OG1  1 
ATOM   11687 C  CG2  . THR H 2 55  ? -0.817  -26.256 38.411  1.00 58.31  ? 55  THR H CG2  1 
ATOM   11688 N  N    . LEU H 2 56  ? 0.503   -30.438 38.707  1.00 65.79  ? 56  LEU H N    1 
ATOM   11689 C  CA   . LEU H 2 56  ? 0.578   -31.916 38.760  1.00 61.82  ? 56  LEU H CA   1 
ATOM   11690 C  C    . LEU H 2 56  ? -0.787  -32.510 38.409  1.00 65.47  ? 56  LEU H C    1 
ATOM   11691 O  O    . LEU H 2 56  ? -0.805  -33.515 37.701  1.00 62.38  ? 56  LEU H O    1 
ATOM   11692 C  CB   . LEU H 2 56  ? 1.048   -32.319 40.156  1.00 54.75  ? 56  LEU H CB   1 
ATOM   11693 C  CG   . LEU H 2 56  ? 2.452   -31.854 40.516  1.00 51.36  ? 56  LEU H CG   1 
ATOM   11694 C  CD1  . LEU H 2 56  ? 2.762   -32.200 41.954  1.00 53.13  ? 56  LEU H CD1  1 
ATOM   11695 C  CD2  . LEU H 2 56  ? 3.476   -32.482 39.590  1.00 47.29  ? 56  LEU H CD2  1 
ATOM   11696 N  N    . SER H 2 57  ? -1.877  -31.904 38.884  1.00 66.39  ? 57  SER H N    1 
ATOM   11697 C  CA   . SER H 2 57  ? -3.214  -32.382 38.527  1.00 65.43  ? 57  SER H CA   1 
ATOM   11698 C  C    . SER H 2 57  ? -3.425  -32.430 37.025  1.00 61.05  ? 57  SER H C    1 
ATOM   11699 O  O    . SER H 2 57  ? -4.133  -33.306 36.522  1.00 64.03  ? 57  SER H O    1 
ATOM   11700 C  CB   . SER H 2 57  ? -4.273  -31.494 39.172  1.00 63.52  ? 57  SER H CB   1 
ATOM   11701 O  OG   . SER H 2 57  ? -3.860  -31.158 40.482  1.00 73.14  ? 57  SER H OG   1 
ATOM   11702 N  N    . ASP H 2 58  ? -2.830  -31.493 36.292  1.00 64.36  ? 58  ASP H N    1 
ATOM   11703 C  CA   . ASP H 2 58  ? -2.899  -31.540 34.835  1.00 67.98  ? 58  ASP H CA   1 
ATOM   11704 C  C    . ASP H 2 58  ? -2.354  -32.838 34.271  1.00 61.65  ? 58  ASP H C    1 
ATOM   11705 O  O    . ASP H 2 58  ? -2.701  -33.198 33.143  1.00 65.52  ? 58  ASP H O    1 
ATOM   11706 C  CB   . ASP H 2 58  ? -2.125  -30.372 34.215  1.00 65.24  ? 58  ASP H CB   1 
ATOM   11707 C  CG   . ASP H 2 58  ? -2.657  -29.039 34.653  1.00 70.98  ? 58  ASP H CG   1 
ATOM   11708 O  OD1  . ASP H 2 58  ? -3.861  -28.988 34.971  1.00 71.72  ? 58  ASP H OD1  1 
ATOM   11709 O  OD2  . ASP H 2 58  ? -1.881  -28.055 34.681  1.00 73.57  ? 58  ASP H OD2  1 
ATOM   11710 N  N    . TYR H 2 59  ? -1.484  -33.527 35.002  1.00 59.32  ? 59  TYR H N    1 
ATOM   11711 C  CA   . TYR H 2 59  ? -0.830  -34.746 34.459  1.00 61.68  ? 59  TYR H CA   1 
ATOM   11712 C  C    . TYR H 2 59  ? -1.290  -36.004 35.203  1.00 62.41  ? 59  TYR H C    1 
ATOM   11713 O  O    . TYR H 2 59  ? -0.713  -37.062 34.936  1.00 61.82  ? 59  TYR H O    1 
ATOM   11714 C  CB   . TYR H 2 59  ? 0.685   -34.595 34.562  1.00 59.86  ? 59  TYR H CB   1 
ATOM   11715 C  CG   . TYR H 2 59  ? 1.308   -33.515 33.720  1.00 58.10  ? 59  TYR H CG   1 
ATOM   11716 C  CD1  . TYR H 2 59  ? 1.452   -33.673 32.354  1.00 54.81  ? 59  TYR H CD1  1 
ATOM   11717 C  CD2  . TYR H 2 59  ? 1.791   -32.354 34.295  1.00 54.89  ? 59  TYR H CD2  1 
ATOM   11718 C  CE1  . TYR H 2 59  ? 2.041   -32.693 31.576  1.00 58.38  ? 59  TYR H CE1  1 
ATOM   11719 C  CE2  . TYR H 2 59  ? 2.381   -31.363 33.532  1.00 56.90  ? 59  TYR H CE2  1 
ATOM   11720 C  CZ   . TYR H 2 59  ? 2.507   -31.535 32.167  1.00 60.14  ? 59  TYR H CZ   1 
ATOM   11721 O  OH   . TYR H 2 59  ? 3.088   -30.572 31.401  1.00 60.01  ? 59  TYR H OH   1 
ATOM   11722 N  N    . ASN H 2 60  ? -2.272  -35.889 36.099  1.00 61.08  ? 60  ASN H N    1 
ATOM   11723 C  CA   . ASN H 2 60  ? -2.798  -37.028 36.907  1.00 67.46  ? 60  ASN H CA   1 
ATOM   11724 C  C    . ASN H 2 60  ? -1.708  -37.568 37.837  1.00 64.47  ? 60  ASN H C    1 
ATOM   11725 O  O    . ASN H 2 60  ? -1.807  -38.738 38.232  1.00 59.32  ? 60  ASN H O    1 
ATOM   11726 C  CB   . ASN H 2 60  ? -3.465  -38.109 36.054  1.00 62.68  ? 60  ASN H CB   1 
ATOM   11727 C  CG   . ASN H 2 60  ? -4.672  -37.606 35.293  1.00 73.76  ? 60  ASN H CG   1 
ATOM   11728 O  OD1  . ASN H 2 60  ? -5.412  -36.755 35.779  1.00 78.91  ? 60  ASN H OD1  1 
ATOM   11729 N  ND2  . ASN H 2 60  ? -4.878  -38.128 34.096  1.00 78.73  ? 60  ASN H ND2  1 
ATOM   11730 N  N    . ILE H 2 61  ? -0.725  -36.736 38.181  1.00 57.18  ? 61  ILE H N    1 
ATOM   11731 C  CA   . ILE H 2 61  ? 0.310   -37.152 39.164  1.00 49.83  ? 61  ILE H CA   1 
ATOM   11732 C  C    . ILE H 2 61  ? -0.361  -37.088 40.526  1.00 55.38  ? 61  ILE H C    1 
ATOM   11733 O  O    . ILE H 2 61  ? -1.017  -36.085 40.826  1.00 56.56  ? 61  ILE H O    1 
ATOM   11734 C  CB   . ILE H 2 61  ? 1.574   -36.277 39.073  1.00 49.31  ? 61  ILE H CB   1 
ATOM   11735 C  CG1  . ILE H 2 61  ? 2.367   -36.578 37.804  1.00 48.98  ? 61  ILE H CG1  1 
ATOM   11736 C  CG2  . ILE H 2 61  ? 2.445   -36.412 40.312  1.00 46.11  ? 61  ILE H CG2  1 
ATOM   11737 C  CD1  . ILE H 2 61  ? 3.066   -35.387 37.224  1.00 51.75  ? 61  ILE H CD1  1 
ATOM   11738 N  N    . GLN H 2 62  ? -0.232  -38.157 41.291  1.00 56.92  ? 62  GLN H N    1 
ATOM   11739 C  CA   . GLN H 2 62  ? -0.878  -38.197 42.586  1.00 55.16  ? 62  GLN H CA   1 
ATOM   11740 C  C    . GLN H 2 62  ? 0.100   -38.859 43.535  1.00 51.96  ? 62  GLN H C    1 
ATOM   11741 O  O    . GLN H 2 62  ? 1.302   -38.906 43.263  1.00 48.65  ? 62  GLN H O    1 
ATOM   11742 C  CB   . GLN H 2 62  ? -2.229  -38.914 42.501  1.00 56.98  ? 62  GLN H CB   1 
ATOM   11743 C  CG   . GLN H 2 62  ? -2.143  -40.310 41.966  1.00 60.70  ? 62  GLN H CG   1 
ATOM   11744 C  CD   . GLN H 2 62  ? -3.355  -40.645 41.126  1.00 72.08  ? 62  GLN H CD   1 
ATOM   11745 O  OE1  . GLN H 2 62  ? -4.252  -39.814 40.974  1.00 77.16  ? 62  GLN H OE1  1 
ATOM   11746 N  NE2  . GLN H 2 62  ? -3.394  -41.861 40.577  1.00 71.35  ? 62  GLN H NE2  1 
ATOM   11747 N  N    . LYS H 2 63  ? -0.424  -39.351 44.653  1.00 58.79  ? 63  LYS H N    1 
ATOM   11748 C  CA   . LYS H 2 63  ? 0.389   -40.042 45.637  1.00 55.85  ? 63  LYS H CA   1 
ATOM   11749 C  C    . LYS H 2 63  ? 1.114   -41.209 44.980  1.00 54.50  ? 63  LYS H C    1 
ATOM   11750 O  O    . LYS H 2 63  ? 0.608   -41.834 44.044  1.00 55.81  ? 63  LYS H O    1 
ATOM   11751 C  CB   . LYS H 2 63  ? -0.490  -40.527 46.803  1.00 57.59  ? 63  LYS H CB   1 
ATOM   11752 C  CG   . LYS H 2 63  ? 0.283   -40.700 48.112  1.00 54.24  ? 63  LYS H CG   1 
ATOM   11753 C  CD   . LYS H 2 63  ? -0.350  -41.700 49.039  1.00 52.02  ? 63  LYS H CD   1 
ATOM   11754 C  CE   . LYS H 2 63  ? 0.487   -41.902 50.315  1.00 56.36  ? 63  LYS H CE   1 
ATOM   11755 N  NZ   . LYS H 2 63  ? 1.651   -42.797 50.137  1.00 52.36  ? 63  LYS H NZ   1 
ATOM   11756 N  N    . GLU H 2 64  ? 2.348   -41.440 45.426  1.00 54.36  ? 64  GLU H N    1 
ATOM   11757 C  CA   . GLU H 2 64  ? 3.165   -42.592 45.032  1.00 56.80  ? 64  GLU H CA   1 
ATOM   11758 C  C    . GLU H 2 64  ? 3.546   -42.620 43.554  1.00 52.22  ? 64  GLU H C    1 
ATOM   11759 O  O    . GLU H 2 64  ? 4.277   -43.521 43.147  1.00 53.58  ? 64  GLU H O    1 
ATOM   11760 C  CB   . GLU H 2 64  ? 2.477   -43.902 45.430  1.00 48.97  ? 64  GLU H CB   1 
ATOM   11761 C  CG   . GLU H 2 64  ? 2.353   -44.012 46.957  1.00 57.60  ? 64  GLU H CG   1 
ATOM   11762 C  CD   . GLU H 2 64  ? 1.518   -45.173 47.438  1.00 58.93  ? 64  GLU H CD   1 
ATOM   11763 O  OE1  . GLU H 2 64  ? 1.378   -46.159 46.684  1.00 62.01  ? 64  GLU H OE1  1 
ATOM   11764 O  OE2  . GLU H 2 64  ? 0.998   -45.101 48.581  1.00 60.39  ? 64  GLU H OE2  1 
ATOM   11765 N  N    . SER H 2 65  ? 3.099   -41.649 42.753  1.00 47.07  ? 65  SER H N    1 
ATOM   11766 C  CA   . SER H 2 65  ? 3.626   -41.497 41.399  1.00 49.88  ? 65  SER H CA   1 
ATOM   11767 C  C    . SER H 2 65  ? 5.129   -41.257 41.422  1.00 48.46  ? 65  SER H C    1 
ATOM   11768 O  O    . SER H 2 65  ? 5.681   -40.682 42.367  1.00 51.36  ? 65  SER H O    1 
ATOM   11769 C  CB   . SER H 2 65  ? 2.955   -40.336 40.643  1.00 52.16  ? 65  SER H CB   1 
ATOM   11770 O  OG   . SER H 2 65  ? 1.534   -40.380 40.674  1.00 55.32  ? 65  SER H OG   1 
ATOM   11771 N  N    . THR H 2 66  ? 5.796   -41.709 40.364  1.00 44.50  ? 66  THR H N    1 
ATOM   11772 C  CA   . THR H 2 66  ? 7.244   -41.611 40.257  1.00 49.64  ? 66  THR H CA   1 
ATOM   11773 C  C    . THR H 2 66  ? 7.600   -40.672 39.115  1.00 50.61  ? 66  THR H C    1 
ATOM   11774 O  O    . THR H 2 66  ? 7.212   -40.912 37.972  1.00 48.12  ? 66  THR H O    1 
ATOM   11775 C  CB   . THR H 2 66  ? 7.881   -42.978 40.033  1.00 50.61  ? 66  THR H CB   1 
ATOM   11776 O  OG1  . THR H 2 66  ? 7.825   -43.722 41.253  1.00 52.47  ? 66  THR H OG1  1 
ATOM   11777 C  CG2  . THR H 2 66  ? 9.339   -42.805 39.594  1.00 52.05  ? 66  THR H CG2  1 
ATOM   11778 N  N    . LEU H 2 67  ? 8.313   -39.598 39.431  1.00 51.74  ? 67  LEU H N    1 
ATOM   11779 C  CA   . LEU H 2 67  ? 8.815   -38.670 38.428  1.00 49.18  ? 67  LEU H CA   1 
ATOM   11780 C  C    . LEU H 2 67  ? 10.283  -38.978 38.195  1.00 50.80  ? 67  LEU H C    1 
ATOM   11781 O  O    . LEU H 2 67  ? 11.025  -39.219 39.154  1.00 52.55  ? 67  LEU H O    1 
ATOM   11782 C  CB   . LEU H 2 67  ? 8.656   -37.221 38.894  1.00 49.70  ? 67  LEU H CB   1 
ATOM   11783 C  CG   . LEU H 2 67  ? 7.349   -36.435 38.710  1.00 54.98  ? 67  LEU H CG   1 
ATOM   11784 C  CD1  . LEU H 2 67  ? 6.102   -37.282 38.950  1.00 49.85  ? 67  LEU H CD1  1 
ATOM   11785 C  CD2  . LEU H 2 67  ? 7.367   -35.208 39.618  1.00 49.37  ? 67  LEU H CD2  1 
ATOM   11786 N  N    . HIS H 2 68  ? 10.710  -38.949 36.928  1.00 50.26  ? 68  HIS H N    1 
ATOM   11787 C  CA   . HIS H 2 68  ? 12.072  -39.333 36.546  1.00 50.80  ? 68  HIS H CA   1 
ATOM   11788 C  C    . HIS H 2 68  ? 12.890  -38.080 36.226  1.00 50.69  ? 68  HIS H C    1 
ATOM   11789 O  O    . HIS H 2 68  ? 12.622  -37.391 35.233  1.00 54.41  ? 68  HIS H O    1 
ATOM   11790 C  CB   . HIS H 2 68  ? 12.040  -40.305 35.368  1.00 45.79  ? 68  HIS H CB   1 
ATOM   11791 C  CG   . HIS H 2 68  ? 11.304  -41.576 35.669  1.00 51.56  ? 68  HIS H CG   1 
ATOM   11792 N  ND1  . HIS H 2 68  ? 11.837  -42.577 36.458  1.00 54.28  ? 68  HIS H ND1  1 
ATOM   11793 C  CD2  . HIS H 2 68  ? 10.055  -41.982 35.336  1.00 43.21  ? 68  HIS H CD2  1 
ATOM   11794 C  CE1  . HIS H 2 68  ? 10.954  -43.548 36.589  1.00 51.25  ? 68  HIS H CE1  1 
ATOM   11795 N  NE2  . HIS H 2 68  ? 9.870   -43.218 35.906  1.00 54.53  ? 68  HIS H NE2  1 
ATOM   11796 N  N    . LEU H 2 69  ? 13.884  -37.787 37.068  1.00 46.59  ? 69  LEU H N    1 
ATOM   11797 C  CA   . LEU H 2 69  ? 14.690  -36.576 36.913  1.00 51.45  ? 69  LEU H CA   1 
ATOM   11798 C  C    . LEU H 2 69  ? 15.852  -36.813 35.955  1.00 53.79  ? 69  LEU H C    1 
ATOM   11799 O  O    . LEU H 2 69  ? 16.513  -37.857 35.990  1.00 53.65  ? 69  LEU H O    1 
ATOM   11800 C  CB   . LEU H 2 69  ? 15.220  -36.089 38.263  1.00 50.31  ? 69  LEU H CB   1 
ATOM   11801 C  CG   . LEU H 2 69  ? 16.039  -34.786 38.314  1.00 60.51  ? 69  LEU H CG   1 
ATOM   11802 C  CD1  . LEU H 2 69  ? 15.244  -33.542 37.852  1.00 52.25  ? 69  LEU H CD1  1 
ATOM   11803 C  CD2  . LEU H 2 69  ? 16.615  -34.566 39.728  1.00 59.66  ? 69  LEU H CD2  1 
ATOM   11804 N  N    . VAL H 2 70  ? 16.107  -35.820 35.109  1.00 56.52  ? 70  VAL H N    1 
ATOM   11805 C  CA   . VAL H 2 70  ? 16.989  -35.972 33.959  1.00 57.01  ? 70  VAL H CA   1 
ATOM   11806 C  C    . VAL H 2 70  ? 17.706  -34.643 33.692  1.00 57.74  ? 70  VAL H C    1 
ATOM   11807 O  O    . VAL H 2 70  ? 17.153  -33.568 33.922  1.00 56.59  ? 70  VAL H O    1 
ATOM   11808 C  CB   . VAL H 2 70  ? 16.134  -36.456 32.767  1.00 53.55  ? 70  VAL H CB   1 
ATOM   11809 C  CG1  . VAL H 2 70  ? 16.707  -36.034 31.476  1.00 55.40  ? 70  VAL H CG1  1 
ATOM   11810 C  CG2  . VAL H 2 70  ? 15.959  -37.975 32.830  1.00 54.05  ? 70  VAL H CG2  1 
ATOM   11811 N  N    . LEU H 2 71  ? 18.937  -34.711 33.195  1.00 55.36  ? 71  LEU H N    1 
ATOM   11812 C  CA   . LEU H 2 71  ? 19.618  -33.465 32.772  1.00 58.36  ? 71  LEU H CA   1 
ATOM   11813 C  C    . LEU H 2 71  ? 19.620  -33.377 31.239  1.00 57.80  ? 71  LEU H C    1 
ATOM   11814 O  O    . LEU H 2 71  ? 18.777  -33.982 30.605  1.00 52.95  ? 71  LEU H O    1 
ATOM   11815 C  CB   . LEU H 2 71  ? 21.036  -33.399 33.353  1.00 55.69  ? 71  LEU H CB   1 
ATOM   11816 C  CG   . LEU H 2 71  ? 21.169  -33.364 34.875  1.00 60.41  ? 71  LEU H CG   1 
ATOM   11817 C  CD1  . LEU H 2 71  ? 22.608  -33.099 35.284  1.00 64.47  ? 71  LEU H CD1  1 
ATOM   11818 C  CD2  . LEU H 2 71  ? 20.254  -32.327 35.496  1.00 56.92  ? 71  LEU H CD2  1 
ATOM   11819 N  N    . ARG H 2 72  ? 20.569  -32.662 30.662  1.00 59.95  ? 72  ARG H N    1 
ATOM   11820 C  CA   . ARG H 2 72  ? 20.590  -32.400 29.225  1.00 66.87  ? 72  ARG H CA   1 
ATOM   11821 C  C    . ARG H 2 72  ? 21.995  -32.634 28.695  1.00 69.88  ? 72  ARG H C    1 
ATOM   11822 O  O    . ARG H 2 72  ? 22.960  -32.074 29.227  1.00 76.10  ? 72  ARG H O    1 
ATOM   11823 C  CB   . ARG H 2 72  ? 20.185  -30.954 28.914  1.00 62.49  ? 72  ARG H CB   1 
ATOM   11824 C  CG   . ARG H 2 72  ? 18.737  -30.703 28.539  1.00 59.44  ? 72  ARG H CG   1 
ATOM   11825 C  CD   . ARG H 2 72  ? 18.497  -29.190 28.222  1.00 58.28  ? 72  ARG H CD   1 
ATOM   11826 N  NE   . ARG H 2 72  ? 17.087  -28.798 28.311  1.00 52.71  ? 72  ARG H NE   1 
ATOM   11827 C  CZ   . ARG H 2 72  ? 16.486  -28.310 29.399  1.00 54.15  ? 72  ARG H CZ   1 
ATOM   11828 N  NH1  . ARG H 2 72  ? 17.163  -28.092 30.515  1.00 54.16  ? 72  ARG H NH1  1 
ATOM   11829 N  NH2  . ARG H 2 72  ? 15.198  -28.013 29.361  1.00 53.58  ? 72  ARG H NH2  1 
ATOM   11830 N  N    . LEU H 2 73  ? 22.116  -33.447 27.650  1.00 66.52  ? 73  LEU H N    1 
ATOM   11831 C  CA   . LEU H 2 73  ? 23.322  -33.438 26.828  1.00 67.55  ? 73  LEU H CA   1 
ATOM   11832 C  C    . LEU H 2 73  ? 22.982  -32.687 25.539  1.00 68.93  ? 73  LEU H C    1 
ATOM   11833 O  O    . LEU H 2 73  ? 22.473  -33.271 24.583  1.00 73.17  ? 73  LEU H O    1 
ATOM   11834 C  CB   . LEU H 2 73  ? 23.821  -34.856 26.579  1.00 66.84  ? 73  LEU H CB   1 
ATOM   11835 C  CG   . LEU H 2 73  ? 24.491  -35.435 27.832  1.00 72.01  ? 73  LEU H CG   1 
ATOM   11836 C  CD1  . LEU H 2 73  ? 25.178  -36.753 27.558  1.00 67.82  ? 73  LEU H CD1  1 
ATOM   11837 C  CD2  . LEU H 2 73  ? 25.492  -34.439 28.406  1.00 71.77  ? 73  LEU H CD2  1 
ATOM   11838 N  N    . ARG H 2 74  ? 23.251  -31.370 25.522  1.00 70.34  ? 74  ARG H N    1 
ATOM   11839 C  CA   . ARG H 2 74  ? 23.043  -30.557 24.318  1.00 70.65  ? 74  ARG H CA   1 
ATOM   11840 C  C    . ARG H 2 74  ? 24.122  -30.853 23.272  1.00 65.88  ? 74  ARG H C    1 
ATOM   11841 O  O    . ARG H 2 74  ? 25.286  -31.091 23.599  1.00 64.14  ? 74  ARG H O    1 
ATOM   11842 C  CB   . ARG H 2 74  ? 23.043  -29.045 24.645  1.00 66.14  ? 74  ARG H CB   1 
ATOM   11843 C  CG   . ARG H 2 74  ? 22.316  -28.608 25.934  1.00 63.22  ? 74  ARG H CG   1 
ATOM   11844 C  CD   . ARG H 2 74  ? 22.044  -27.066 26.054  1.00 60.07  ? 74  ARG H CD   1 
ATOM   11845 N  NE   . ARG H 2 74  ? 20.675  -26.689 25.639  1.00 64.05  ? 74  ARG H NE   1 
ATOM   11846 C  CZ   . ARG H 2 74  ? 19.662  -26.390 26.463  1.00 61.60  ? 74  ARG H CZ   1 
ATOM   11847 N  NH1  . ARG H 2 74  ? 19.817  -26.391 27.784  1.00 66.86  ? 74  ARG H NH1  1 
ATOM   11848 N  NH2  . ARG H 2 74  ? 18.473  -26.084 25.963  1.00 63.76  ? 74  ARG H NH2  1 
ATOM   11849 N  N    . GLY H 2 75  ? 23.742  -30.833 22.004  1.00 66.39  ? 75  GLY H N    1 
ATOM   11850 C  CA   . GLY H 2 75  ? 24.717  -31.141 20.970  1.00 62.69  ? 75  GLY H CA   1 
ATOM   11851 C  C    . GLY H 2 75  ? 24.434  -30.393 19.695  1.00 65.65  ? 75  GLY H C    1 
ATOM   11852 O  O    . GLY H 2 75  ? 23.290  -29.997 19.484  1.00 67.27  ? 75  GLY H O    1 
HETATM 11853 CL CL19 . SRE I 3 .   ? 72.950  -8.994  22.154  1.00 63.42  ? 601 SRE C CL19 1 
HETATM 11854 C  C16  . SRE I 3 .   ? 73.997  -8.226  21.009  1.00 59.51  ? 601 SRE C C16  1 
HETATM 11855 C  C15  . SRE I 3 .   ? 75.136  -7.566  21.434  1.00 61.63  ? 601 SRE C C15  1 
HETATM 11856 CL CL20 . SRE I 3 .   ? 75.533  -7.493  23.112  1.00 71.90  ? 601 SRE C CL20 1 
HETATM 11857 C  C17  . SRE I 3 .   ? 73.698  -8.272  19.662  1.00 62.41  ? 601 SRE C C17  1 
HETATM 11858 C  C18  . SRE I 3 .   ? 74.541  -7.665  18.747  1.00 61.79  ? 601 SRE C C18  1 
HETATM 11859 C  C13  . SRE I 3 .   ? 75.692  -7.005  19.161  1.00 67.30  ? 601 SRE C C13  1 
HETATM 11860 C  C14  . SRE I 3 .   ? 75.979  -6.960  20.518  1.00 60.38  ? 601 SRE C C14  1 
HETATM 11861 C  C4   . SRE I 3 .   ? 76.602  -6.290  18.168  1.00 64.96  ? 601 SRE C C4   1 
HETATM 11862 C  C5   . SRE I 3 .   ? 77.492  -7.192  17.334  1.00 65.52  ? 601 SRE C C5   1 
HETATM 11863 C  C6   . SRE I 3 .   ? 77.999  -8.367  17.905  1.00 61.35  ? 601 SRE C C6   1 
HETATM 11864 C  C7   . SRE I 3 .   ? 78.830  -9.204  17.183  1.00 61.07  ? 601 SRE C C7   1 
HETATM 11865 C  C8   . SRE I 3 .   ? 79.184  -8.863  15.891  1.00 65.89  ? 601 SRE C C8   1 
HETATM 11866 C  C9   . SRE I 3 .   ? 78.701  -7.699  15.321  1.00 61.54  ? 601 SRE C C9   1 
HETATM 11867 C  C10  . SRE I 3 .   ? 77.849  -6.850  16.024  1.00 65.37  ? 601 SRE C C10  1 
HETATM 11868 C  C1   . SRE I 3 .   ? 77.355  -5.581  15.338  1.00 69.73  ? 601 SRE C C1   1 
HETATM 11869 N  N11  . SRE I 3 .   ? 76.530  -5.906  14.151  1.00 67.21  ? 601 SRE C N11  1 
HETATM 11870 C  C12  . SRE I 3 .   ? 75.261  -6.613  14.348  1.00 67.96  ? 601 SRE C C12  1 
HETATM 11871 C  C2   . SRE I 3 .   ? 76.724  -4.593  16.320  1.00 65.70  ? 601 SRE C C2   1 
HETATM 11872 C  C3   . SRE I 3 .   ? 75.812  -5.306  17.295  1.00 70.64  ? 601 SRE C C3   1 
HETATM 11873 CL CL19 . SRE J 3 .   ? 13.995  -30.198 22.919  1.00 79.35  ? 601 SRE G CL19 1 
HETATM 11874 C  C16  . SRE J 3 .   ? 12.757  -29.568 21.888  1.00 65.85  ? 601 SRE G C16  1 
HETATM 11875 C  C15  . SRE J 3 .   ? 13.117  -29.072 20.654  1.00 71.39  ? 601 SRE G C15  1 
HETATM 11876 CL CL20 . SRE J 3 .   ? 14.773  -29.090 20.178  1.00 90.24  ? 601 SRE G CL20 1 
HETATM 11877 C  C17  . SRE J 3 .   ? 11.431  -29.556 22.272  1.00 59.25  ? 601 SRE G C17  1 
HETATM 11878 C  C18  . SRE J 3 .   ? 10.475  -29.055 21.401  1.00 69.72  ? 601 SRE G C18  1 
HETATM 11879 C  C13  . SRE J 3 .   ? 10.826  -28.549 20.153  1.00 68.80  ? 601 SRE G C13  1 
HETATM 11880 C  C14  . SRE J 3 .   ? 12.162  -28.571 19.788  1.00 71.91  ? 601 SRE G C14  1 
HETATM 11881 C  C4   . SRE J 3 .   ? 9.804   -27.986 19.172  1.00 71.90  ? 601 SRE G C4   1 
HETATM 11882 C  C5   . SRE J 3 .   ? 8.613   -28.894 18.939  1.00 74.61  ? 601 SRE G C5   1 
HETATM 11883 C  C6   . SRE J 3 .   ? 8.821   -30.135 18.330  1.00 69.65  ? 601 SRE G C6   1 
HETATM 11884 C  C7   . SRE J 3 .   ? 7.764   -30.992 18.092  1.00 69.22  ? 601 SRE G C7   1 
HETATM 11885 C  C8   . SRE J 3 .   ? 6.491   -30.629 18.478  1.00 69.37  ? 601 SRE G C8   1 
HETATM 11886 C  C9   . SRE J 3 .   ? 6.275   -29.409 19.086  1.00 71.43  ? 601 SRE G C9   1 
HETATM 11887 C  C10  . SRE J 3 .   ? 7.322   -28.522 19.315  1.00 75.49  ? 601 SRE G C10  1 
HETATM 11888 C  C1   . SRE J 3 .   ? 7.021   -27.211 20.026  1.00 72.91  ? 601 SRE G C1   1 
HETATM 11889 N  N11  . SRE J 3 .   ? 6.151   -27.491 21.178  1.00 83.90  ? 601 SRE G N11  1 
HETATM 11890 C  C12  . SRE J 3 .   ? 6.058   -26.426 22.180  1.00 85.59  ? 601 SRE G C12  1 
HETATM 11891 C  C2   . SRE J 3 .   ? 8.288   -26.535 20.540  1.00 74.17  ? 601 SRE G C2   1 
HETATM 11892 C  C3   . SRE J 3 .   ? 9.362   -26.548 19.479  1.00 74.55  ? 601 SRE G C3   1 
HETATM 11893 O  O    . HOH K 4 .   ? 34.660  -1.313  19.466  1.00 52.25  ? 601 HOH A O    1 
HETATM 11894 O  O    . HOH K 4 .   ? 24.818  -5.334  45.289  1.00 64.57  ? 602 HOH A O    1 
HETATM 11895 O  O    . HOH K 4 .   ? 31.832  22.750  27.870  1.00 72.28  ? 603 HOH A O    1 
HETATM 11896 O  O    . HOH K 4 .   ? 32.687  -9.833  6.388   1.00 43.11  ? 604 HOH A O    1 
HETATM 11897 O  O    . HOH K 4 .   ? 6.846   -4.301  15.070  1.00 65.29  ? 605 HOH A O    1 
HETATM 11898 O  O    . HOH K 4 .   ? 27.521  -14.689 5.719   1.00 52.83  ? 606 HOH A O    1 
HETATM 11899 O  O    . HOH K 4 .   ? 34.066  -2.110  16.658  1.00 51.29  ? 607 HOH A O    1 
HETATM 11900 O  O    . HOH K 4 .   ? 36.454  2.023   25.542  1.00 56.42  ? 608 HOH A O    1 
HETATM 11901 O  O    . HOH K 4 .   ? 33.879  -14.464 6.631   1.00 46.83  ? 609 HOH A O    1 
HETATM 11902 O  O    . HOH K 4 .   ? 33.166  5.914   -5.031  1.00 44.89  ? 610 HOH A O    1 
HETATM 11903 O  O    . HOH K 4 .   ? 38.421  -2.452  15.541  1.00 37.08  ? 611 HOH A O    1 
HETATM 11904 O  O    . HOH K 4 .   ? 26.783  -14.718 3.243   1.00 52.07  ? 612 HOH A O    1 
HETATM 11905 O  O    . HOH L 4 .   ? 31.494  5.040   -1.133  1.00 69.13  ? 101 HOH B O    1 
HETATM 11906 O  O    . HOH L 4 .   ? 31.074  18.754  8.944   1.00 60.48  ? 102 HOH B O    1 
HETATM 11907 O  O    . HOH L 4 .   ? 28.322  3.037   1.931   1.00 54.63  ? 103 HOH B O    1 
HETATM 11908 O  O    . HOH L 4 .   ? 50.067  13.853  17.421  1.00 62.98  ? 104 HOH B O    1 
HETATM 11909 O  O    . HOH L 4 .   ? 25.811  15.551  15.772  1.00 43.35  ? 105 HOH B O    1 
HETATM 11910 O  O    . HOH L 4 .   ? 38.725  -2.887  13.332  1.00 50.82  ? 106 HOH B O    1 
HETATM 11911 O  O    . HOH L 4 .   ? 52.688  3.991   16.565  1.00 58.09  ? 107 HOH B O    1 
HETATM 11912 O  O    . HOH L 4 .   ? 42.546  3.479   -1.442  1.00 47.38  ? 108 HOH B O    1 
HETATM 11913 O  O    . HOH L 4 .   ? 36.189  -1.459  17.021  1.00 42.44  ? 109 HOH B O    1 
HETATM 11914 O  O    . HOH M 4 .   ? 82.377  -37.934 36.631  1.00 73.80  ? 701 HOH C O    1 
HETATM 11915 O  O    . HOH M 4 .   ? 73.007  -37.352 33.473  1.00 61.00  ? 702 HOH C O    1 
HETATM 11916 O  O    . HOH M 4 .   ? 56.478  -31.345 16.714  1.00 45.67  ? 703 HOH C O    1 
HETATM 11917 O  O    . HOH M 4 .   ? 69.440  -21.981 15.609  1.00 44.18  ? 704 HOH C O    1 
HETATM 11918 O  O    . HOH M 4 .   ? 57.344  -35.384 15.062  1.00 53.40  ? 705 HOH C O    1 
HETATM 11919 O  O    . HOH M 4 .   ? 75.980  -28.859 8.790   1.00 57.73  ? 706 HOH C O    1 
HETATM 11920 O  O    . HOH M 4 .   ? 94.105  -23.707 42.011  1.00 74.21  ? 707 HOH C O    1 
HETATM 11921 O  O    . HOH M 4 .   ? 89.447  -33.365 27.404  1.00 65.81  ? 708 HOH C O    1 
HETATM 11922 O  O    . HOH M 4 .   ? 73.959  -26.263 18.611  1.00 46.56  ? 709 HOH C O    1 
HETATM 11923 O  O    . HOH M 4 .   ? 99.963  4.223   28.630  1.00 79.30  ? 710 HOH C O    1 
HETATM 11924 O  O    . HOH M 4 .   ? 85.622  -38.471 21.688  1.00 58.55  ? 711 HOH C O    1 
HETATM 11925 O  O    . HOH M 4 .   ? 77.221  -0.576  15.486  1.00 67.55  ? 712 HOH C O    1 
HETATM 11926 O  O    . HOH N 4 .   ? 63.743  -5.892  25.953  1.00 55.33  ? 101 HOH D O    1 
HETATM 11927 O  O    . HOH N 4 .   ? 65.483  -8.608  16.979  1.00 52.92  ? 102 HOH D O    1 
HETATM 11928 O  O    . HOH O 4 .   ? 85.156  -48.317 27.330  1.00 76.99  ? 601 HOH E O    1 
HETATM 11929 O  O    . HOH O 4 .   ? 65.651  -61.867 55.735  1.00 58.48  ? 602 HOH E O    1 
HETATM 11930 O  O    . HOH O 4 .   ? 103.835 -61.638 53.974  1.00 52.48  ? 603 HOH E O    1 
HETATM 11931 O  O    . HOH O 4 .   ? 83.804  -64.928 35.816  1.00 56.07  ? 604 HOH E O    1 
HETATM 11932 O  O    . HOH O 4 .   ? 110.959 -68.399 49.049  1.00 60.47  ? 605 HOH E O    1 
HETATM 11933 O  O    . HOH O 4 .   ? 58.149  -41.359 49.879  1.00 74.80  ? 606 HOH E O    1 
HETATM 11934 O  O    . HOH O 4 .   ? 100.214 -56.908 36.198  1.00 55.64  ? 607 HOH E O    1 
HETATM 11935 O  O    . HOH O 4 .   ? 68.366  -62.780 56.332  1.00 53.03  ? 608 HOH E O    1 
HETATM 11936 O  O    . HOH O 4 .   ? 90.132  -79.451 46.666  1.00 58.75  ? 609 HOH E O    1 
HETATM 11937 O  O    . HOH O 4 .   ? 83.606  -63.743 54.159  1.00 50.98  ? 610 HOH E O    1 
HETATM 11938 O  O    . HOH P 4 .   ? 91.374  -67.624 54.451  1.00 55.54  ? 101 HOH F O    1 
HETATM 11939 O  O    . HOH P 4 .   ? 85.910  -63.489 52.323  1.00 46.05  ? 102 HOH F O    1 
HETATM 11940 O  O    . HOH P 4 .   ? 80.440  -47.305 39.217  1.00 58.64  ? 103 HOH F O    1 
HETATM 11941 O  O    . HOH P 4 .   ? 79.076  -46.779 32.774  1.00 42.00  ? 104 HOH F O    1 
HETATM 11942 O  O    . HOH P 4 .   ? 79.625  -48.933 41.498  1.00 53.00  ? 105 HOH F O    1 
HETATM 11943 O  O    . HOH Q 4 .   ? 12.231  -54.649 42.139  1.00 54.07  ? 701 HOH G O    1 
HETATM 11944 O  O    . HOH Q 4 .   ? 13.275  -44.412 34.001  1.00 56.71  ? 702 HOH G O    1 
HETATM 11945 O  O    . HOH Q 4 .   ? 35.311  -46.303 32.855  1.00 69.04  ? 703 HOH G O    1 
HETATM 11946 O  O    . HOH Q 4 .   ? 4.203   -39.153 60.606  1.00 65.26  ? 704 HOH G O    1 
HETATM 11947 O  O    . HOH Q 4 .   ? 31.483  -55.633 9.037   1.00 69.00  ? 705 HOH G O    1 
HETATM 11948 O  O    . HOH Q 4 .   ? 11.538  -45.841 5.947   1.00 68.98  ? 706 HOH G O    1 
HETATM 11949 O  O    . HOH Q 4 .   ? 31.612  -56.696 11.804  1.00 73.64  ? 707 HOH G O    1 
HETATM 11950 O  O    . HOH Q 4 .   ? 9.170   -44.106 6.616   1.00 69.14  ? 708 HOH G O    1 
HETATM 11951 O  O    . HOH R 4 .   ? 12.025  -30.277 49.070  1.00 50.16  ? 101 HOH H O    1 
HETATM 11952 O  O    . HOH R 4 .   ? 17.216  -21.784 37.867  1.00 59.09  ? 102 HOH H O    1 
HETATM 11953 O  O    . HOH R 4 .   ? 15.734  -25.701 26.134  1.00 52.85  ? 103 HOH H O    1 
HETATM 11954 O  O    . HOH R 4 .   ? 20.892  -26.631 30.573  1.00 53.45  ? 104 HOH H O    1 
HETATM 11955 O  O    . HOH R 4 .   ? 14.522  -23.612 46.168  1.00 46.79  ? 105 HOH H O    1 
HETATM 11956 O  O    . HOH R 4 .   ? 12.827  -23.478 34.532  1.00 56.87  ? 106 HOH H O    1 
HETATM 11957 O  O    . HOH R 4 .   ? 17.363  -45.963 38.090  1.00 54.56  ? 107 HOH H O    1 
# 
